Download the predictions

Files

Predictor	Description	File
Metapredictor (MDN)	Prediction of the pathogenicity of missense variants of BRCA2 in TSV format
BRCA2 domain specific (MLR)	Prediction of the functional HDR assay of missense variants of BRCA2 residues 2470 - 3197 in TSV format

REST API

List of predictors

Predictors of BRCA2


    import requests
    r = requests.get('https://www.biotoclin.org/predictor/BRCA2/api/')
    r.json()


    curl --request GET --url 'https://www.biotoclin.org/predictor/BRCA2/api/'


    wget -q 'https://www.biotoclin.org/predictor/BRCA2/api/' -O -

Predictions of BRCA2 variants

Predictions of all missense variants of BRCA2 with a certain predictor


    import requests
    r = requests.get('https://www.biotoclin.org/predictor/BRCA2/api/<predictor>/')
    r.json()


    curl  --request GET --url 'https://www.biotoclin.org/predictor/BRCA2/api/<predictor>/'


    wget -q 'https://www.biotoclin.org/predictor/BRCA2/api/<predictor>/' -O -

The parameter is:

predictor: the name of the predictor such as Pathogenicity. The list of available predictors can be downloaded in the section "List of predictors"

Prediction of a single variant

Prediction of a missense variant of BRCA2 with a certain predictor


    import requests
    r = requests.get('https://www.biotoclin.org/predictor/BRCA2/api/<predictor>/<variant>/')
    r.json()


    curl  --request GET --url 'https://www.biotoclin.org/predictor/BRCA2/api/<predictor>/<variant>/'


    wget -q 'https://www.biotoclin.org/predictor/BRCA2/api/<predictor>/<variant>/' -O -

The parameters:

predictor: the name of the predictor such as Pathogenicity. The list of available predictors can be downloaded in the section "List of predictors"
variant: missense variant in one letter format, that is, if your first residue has mutated from a methionine (M) to an alanine (A), the variant will be M1A

License

BRASS data is licensed under a
Creative Commons Attribution-ShareAlike 4.0 International License

Disclaimer This resource is uniquely intended for research purposes. The authors are not responsible for neither its use nor misuse. The data provided are not intended as advice of any kind. The authors have worked with care in the development of this server, but assume no liability or responsibility for any error, weakness, incompleteness or temporariness of the resource and of the data provided.