Gene	UniProt	Variant	Prediction	Score
NOTCH3	Q9UM47-1.2	M1A	Neutral	0.35
NOTCH3	Q9UM47-1.2	M1C	Neutral	0.365
NOTCH3	Q9UM47-1.2	M1D	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	M1E	Pathogenic	0.744
NOTCH3	Q9UM47-1.2	M1F	Neutral	0.123
NOTCH3	Q9UM47-1.2	M1G	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	M1H	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	M1I	Neutral	0.031
NOTCH3	Q9UM47-1.2	M1K	Neutral	0.394
NOTCH3	Q9UM47-1.2	M1L	Neutral	0.007
NOTCH3	Q9UM47-1.2	M1N	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	M1P	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	M1Q	Neutral	0.124
NOTCH3	Q9UM47-1.2	M1R	Neutral	0.382
NOTCH3	Q9UM47-1.2	M1S	Neutral	0.356
NOTCH3	Q9UM47-1.2	M1T	Neutral	0.373
NOTCH3	Q9UM47-1.2	M1V	Neutral	0.029
NOTCH3	Q9UM47-1.2	M1W	Neutral	0.366
NOTCH3	Q9UM47-1.2	M1Y	Neutral	0.384
NOTCH3	Q9UM47-1.2	G2A	Neutral	0.006
NOTCH3	Q9UM47-1.2	G2C	Neutral	0.352
NOTCH3	Q9UM47-1.2	G2D	Neutral	0.025
NOTCH3	Q9UM47-1.2	G2E	Neutral	0.098
NOTCH3	Q9UM47-1.2	G2F	Neutral	0.312
NOTCH3	Q9UM47-1.2	G2H	Neutral	0.095
NOTCH3	Q9UM47-1.2	G2I	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	G2K	Neutral	0.09
NOTCH3	Q9UM47-1.2	G2L	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	G2M	Neutral	0.32
NOTCH3	Q9UM47-1.2	G2N	Neutral	0.005
NOTCH3	Q9UM47-1.2	G2P	Neutral	0.105
NOTCH3	Q9UM47-1.2	G2Q	Neutral	0.096
NOTCH3	Q9UM47-1.2	G2R	Neutral	0.086
NOTCH3	Q9UM47-1.2	G2S	Neutral	0.006
NOTCH3	Q9UM47-1.2	G2T	Neutral	0.104
NOTCH3	Q9UM47-1.2	G2V	Neutral	0.336
NOTCH3	Q9UM47-1.2	G2W	Neutral	0.082
NOTCH3	Q9UM47-1.2	G2Y	Neutral	0.305
NOTCH3	Q9UM47-1.2	P3A	Neutral	0.041
NOTCH3	Q9UM47-1.2	P3C	Neutral	0.489
NOTCH3	Q9UM47-1.2	P3D	Neutral	0.045
NOTCH3	Q9UM47-1.2	P3E	Neutral	0.042
NOTCH3	Q9UM47-1.2	P3F	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	P3G	Neutral	0.154
NOTCH3	Q9UM47-1.2	P3H	Neutral	0.161
NOTCH3	Q9UM47-1.2	P3I	Neutral	0.462
NOTCH3	Q9UM47-1.2	P3K	Neutral	0.038
NOTCH3	Q9UM47-1.2	P3L	Neutral	0.462
NOTCH3	Q9UM47-1.2	P3M	Neutral	0.158
NOTCH3	Q9UM47-1.2	P3N	Neutral	0.174
NOTCH3	Q9UM47-1.2	P3Q	Neutral	0.041
NOTCH3	Q9UM47-1.2	P3R	Neutral	0.147
NOTCH3	Q9UM47-1.2	P3S	Neutral	0.042
NOTCH3	Q9UM47-1.2	P3T	Neutral	0.044
NOTCH3	Q9UM47-1.2	P3V	Neutral	0.168
NOTCH3	Q9UM47-1.2	P3W	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	P3Y	Neutral	0.444
NOTCH3	Q9UM47-1.2	G4A	Neutral	0.006
NOTCH3	Q9UM47-1.2	G4C	Neutral	0.35
NOTCH3	Q9UM47-1.2	G4D	Neutral	0.025
NOTCH3	Q9UM47-1.2	G4E	Neutral	0.097
NOTCH3	Q9UM47-1.2	G4F	Neutral	0.31
NOTCH3	Q9UM47-1.2	G4H	Neutral	0.094
NOTCH3	Q9UM47-1.2	G4I	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	G4K	Neutral	0.089
NOTCH3	Q9UM47-1.2	G4L	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	G4M	Neutral	0.318
NOTCH3	Q9UM47-1.2	G4N	Neutral	0.005
NOTCH3	Q9UM47-1.2	G4P	Neutral	0.104
NOTCH3	Q9UM47-1.2	G4Q	Neutral	0.095
NOTCH3	Q9UM47-1.2	G4R	Neutral	0.085
NOTCH3	Q9UM47-1.2	G4S	Neutral	0.006
NOTCH3	Q9UM47-1.2	G4T	Neutral	0.103
NOTCH3	Q9UM47-1.2	G4V	Neutral	0.334
NOTCH3	Q9UM47-1.2	G4W	Neutral	0.082
NOTCH3	Q9UM47-1.2	G4Y	Neutral	0.303
NOTCH3	Q9UM47-1.2	A5C	Neutral	0.006
NOTCH3	Q9UM47-1.2	A5D	Neutral	0.108
NOTCH3	Q9UM47-1.2	A5E	Neutral	0.024
NOTCH3	Q9UM47-1.2	A5F	Neutral	0.093
NOTCH3	Q9UM47-1.2	A5G	Neutral	0.006
NOTCH3	Q9UM47-1.2	A5H	Neutral	0.098
NOTCH3	Q9UM47-1.2	A5I	Neutral	0.023
NOTCH3	Q9UM47-1.2	A5K	Neutral	0.022
NOTCH3	Q9UM47-1.2	A5L	Neutral	0.023
NOTCH3	Q9UM47-1.2	A5M	Neutral	0.023
NOTCH3	Q9UM47-1.2	A5N	Neutral	0.106
NOTCH3	Q9UM47-1.2	A5P	Neutral	0.026
NOTCH3	Q9UM47-1.2	A5Q	Neutral	0.024
NOTCH3	Q9UM47-1.2	A5R	Neutral	0.021
NOTCH3	Q9UM47-1.2	A5S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A5T	Neutral	0.006
NOTCH3	Q9UM47-1.2	A5V	Neutral	0.005
NOTCH3	Q9UM47-1.2	A5W	Neutral	0.296
NOTCH3	Q9UM47-1.2	A5Y	Neutral	0.09
NOTCH3	Q9UM47-1.2	R6A	Neutral	0.101
NOTCH3	Q9UM47-1.2	R6C	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	R6D	Neutral	0.357
NOTCH3	Q9UM47-1.2	R6E	Neutral	0.028
NOTCH3	Q9UM47-1.2	R6F	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	R6G	Neutral	0.321
NOTCH3	Q9UM47-1.2	R6H	Neutral	0.029
NOTCH3	Q9UM47-1.2	R6I	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	R6K	Neutral	0.002
NOTCH3	Q9UM47-1.2	R6L	Neutral	0.392
NOTCH3	Q9UM47-1.2	R6M	Neutral	0.124
NOTCH3	Q9UM47-1.2	R6N	Neutral	0.027
NOTCH3	Q9UM47-1.2	R6P	Neutral	0.359
NOTCH3	Q9UM47-1.2	R6Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	R6S	Neutral	0.103
NOTCH3	Q9UM47-1.2	R6T	Neutral	0.11
NOTCH3	Q9UM47-1.2	R6V	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	R6W	Pathogenic	0.753
NOTCH3	Q9UM47-1.2	R6Y	Neutral	0.406
NOTCH3	Q9UM47-1.2	G7A	Neutral	0.007
NOTCH3	Q9UM47-1.2	G7C	Neutral	0.383
NOTCH3	Q9UM47-1.2	G7D	Neutral	0.028
NOTCH3	Q9UM47-1.2	G7E	Neutral	0.111
NOTCH3	Q9UM47-1.2	G7F	Neutral	0.341
NOTCH3	Q9UM47-1.2	G7H	Neutral	0.107
NOTCH3	Q9UM47-1.2	G7I	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	G7K	Neutral	0.101
NOTCH3	Q9UM47-1.2	G7L	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	G7M	Neutral	0.349
NOTCH3	Q9UM47-1.2	G7N	Neutral	0.006
NOTCH3	Q9UM47-1.2	G7P	Neutral	0.118
NOTCH3	Q9UM47-1.2	G7Q	Neutral	0.108
NOTCH3	Q9UM47-1.2	G7R	Neutral	0.097
NOTCH3	Q9UM47-1.2	G7S	Neutral	0.007
NOTCH3	Q9UM47-1.2	G7T	Neutral	0.116
NOTCH3	Q9UM47-1.2	G7V	Neutral	0.366
NOTCH3	Q9UM47-1.2	G7W	Neutral	0.093
NOTCH3	Q9UM47-1.2	G7Y	Neutral	0.334
NOTCH3	Q9UM47-1.2	R8A	Neutral	0.088
NOTCH3	Q9UM47-1.2	R8C	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	R8D	Neutral	0.322
NOTCH3	Q9UM47-1.2	R8E	Neutral	0.024
NOTCH3	Q9UM47-1.2	R8F	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	R8G	Neutral	0.289
NOTCH3	Q9UM47-1.2	R8H	Neutral	0.025
NOTCH3	Q9UM47-1.2	R8I	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	R8K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R8L	Neutral	0.356
NOTCH3	Q9UM47-1.2	R8M	Neutral	0.108
NOTCH3	Q9UM47-1.2	R8N	Neutral	0.023
NOTCH3	Q9UM47-1.2	R8P	Neutral	0.324
NOTCH3	Q9UM47-1.2	R8Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	R8S	Neutral	0.089
NOTCH3	Q9UM47-1.2	R8T	Neutral	0.096
NOTCH3	Q9UM47-1.2	R8V	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	R8W	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	R8Y	Neutral	0.369
NOTCH3	Q9UM47-1.2	R9A	Neutral	0.057
NOTCH3	Q9UM47-1.2	R9C	Pathogenic	0.577
NOTCH3	Q9UM47-1.2	R9D	Neutral	0.232
NOTCH3	Q9UM47-1.2	R9E	Neutral	0.015
NOTCH3	Q9UM47-1.2	R9F	Pathogenic	0.624
NOTCH3	Q9UM47-1.2	R9G	Neutral	0.205
NOTCH3	Q9UM47-1.2	R9H	Neutral	0.016
NOTCH3	Q9UM47-1.2	R9I	Pathogenic	0.614
NOTCH3	Q9UM47-1.2	R9K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R9L	Neutral	0.259
NOTCH3	Q9UM47-1.2	R9M	Neutral	0.071
NOTCH3	Q9UM47-1.2	R9N	Neutral	0.015
NOTCH3	Q9UM47-1.2	R9P	Neutral	0.233
NOTCH3	Q9UM47-1.2	R9Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R9S	Neutral	0.059
NOTCH3	Q9UM47-1.2	R9T	Neutral	0.063
NOTCH3	Q9UM47-1.2	R9V	Pathogenic	0.596
NOTCH3	Q9UM47-1.2	R9W	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	R9Y	Neutral	0.271
NOTCH3	Q9UM47-1.2	R10A	Neutral	0.053
NOTCH3	Q9UM47-1.2	R10C	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	R10D	Neutral	0.218
NOTCH3	Q9UM47-1.2	R10E	Neutral	0.014
NOTCH3	Q9UM47-1.2	R10F	Pathogenic	0.605
NOTCH3	Q9UM47-1.2	R10G	Neutral	0.192
NOTCH3	Q9UM47-1.2	R10H	Neutral	0.015
NOTCH3	Q9UM47-1.2	R10I	Pathogenic	0.595
NOTCH3	Q9UM47-1.2	R10K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R10L	Neutral	0.244
NOTCH3	Q9UM47-1.2	R10M	Neutral	0.066
NOTCH3	Q9UM47-1.2	R10N	Neutral	0.014
NOTCH3	Q9UM47-1.2	R10P	Neutral	0.219
NOTCH3	Q9UM47-1.2	R10Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R10S	Neutral	0.054
NOTCH3	Q9UM47-1.2	R10T	Neutral	0.058
NOTCH3	Q9UM47-1.2	R10V	Pathogenic	0.576
NOTCH3	Q9UM47-1.2	R10W	Pathogenic	0.604
NOTCH3	Q9UM47-1.2	R10Y	Neutral	0.255
NOTCH3	Q9UM47-1.2	R11A	Neutral	0.05
NOTCH3	Q9UM47-1.2	R11C	Pathogenic	0.542
NOTCH3	Q9UM47-1.2	R11D	Neutral	0.207
NOTCH3	Q9UM47-1.2	R11E	Neutral	0.013
NOTCH3	Q9UM47-1.2	R11F	Pathogenic	0.59
NOTCH3	Q9UM47-1.2	R11G	Neutral	0.182
NOTCH3	Q9UM47-1.2	R11H	Neutral	0.014
NOTCH3	Q9UM47-1.2	R11I	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	R11K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R11L	Neutral	0.233
NOTCH3	Q9UM47-1.2	R11M	Neutral	0.062
NOTCH3	Q9UM47-1.2	R11N	Neutral	0.013
NOTCH3	Q9UM47-1.2	R11P	Neutral	0.209
NOTCH3	Q9UM47-1.2	R11Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R11S	Neutral	0.051
NOTCH3	Q9UM47-1.2	R11T	Neutral	0.055
NOTCH3	Q9UM47-1.2	R11V	Pathogenic	0.561
NOTCH3	Q9UM47-1.2	R11W	Pathogenic	0.589
NOTCH3	Q9UM47-1.2	R11Y	Neutral	0.243
NOTCH3	Q9UM47-1.2	R12A	Neutral	0.048
NOTCH3	Q9UM47-1.2	R12C	Pathogenic	0.528
NOTCH3	Q9UM47-1.2	R12D	Neutral	0.198
NOTCH3	Q9UM47-1.2	R12E	Neutral	0.013
NOTCH3	Q9UM47-1.2	R12F	Pathogenic	0.577
NOTCH3	Q9UM47-1.2	R12G	Neutral	0.174
NOTCH3	Q9UM47-1.2	R12H	Neutral	0.013
NOTCH3	Q9UM47-1.2	R12I	Pathogenic	0.566
NOTCH3	Q9UM47-1.2	R12K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R12L	Neutral	0.223
NOTCH3	Q9UM47-1.2	R12M	Neutral	0.059
NOTCH3	Q9UM47-1.2	R12N	Neutral	0.012
NOTCH3	Q9UM47-1.2	R12P	Neutral	0.2
NOTCH3	Q9UM47-1.2	R12Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R12S	Neutral	0.049
NOTCH3	Q9UM47-1.2	R12T	Neutral	0.052
NOTCH3	Q9UM47-1.2	R12V	Pathogenic	0.547
NOTCH3	Q9UM47-1.2	R12W	Pathogenic	0.576
NOTCH3	Q9UM47-1.2	R12Y	Neutral	0.233
NOTCH3	Q9UM47-1.2	R13A	Neutral	0.052
NOTCH3	Q9UM47-1.2	R13C	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	R13D	Neutral	0.215
NOTCH3	Q9UM47-1.2	R13E	Neutral	0.014
NOTCH3	Q9UM47-1.2	R13F	Pathogenic	0.601
NOTCH3	Q9UM47-1.2	R13G	Neutral	0.189
NOTCH3	Q9UM47-1.2	R13H	Neutral	0.015
NOTCH3	Q9UM47-1.2	R13I	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	R13K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R13L	Neutral	0.241
NOTCH3	Q9UM47-1.2	R13M	Neutral	0.065
NOTCH3	Q9UM47-1.2	R13N	Neutral	0.013
NOTCH3	Q9UM47-1.2	R13P	Neutral	0.216
NOTCH3	Q9UM47-1.2	R13Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R13S	Neutral	0.053
NOTCH3	Q9UM47-1.2	R13T	Neutral	0.058
NOTCH3	Q9UM47-1.2	R13V	Pathogenic	0.572
NOTCH3	Q9UM47-1.2	R13W	Pathogenic	0.6
NOTCH3	Q9UM47-1.2	R13Y	Neutral	0.252
NOTCH3	Q9UM47-1.2	P14A	Neutral	0.014
NOTCH3	Q9UM47-1.2	P14C	Neutral	0.243
NOTCH3	Q9UM47-1.2	P14D	Neutral	0.016
NOTCH3	Q9UM47-1.2	P14E	Neutral	0.015
NOTCH3	Q9UM47-1.2	P14F	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	P14G	Neutral	0.058
NOTCH3	Q9UM47-1.2	P14H	Neutral	0.061
NOTCH3	Q9UM47-1.2	P14I	Neutral	0.224
NOTCH3	Q9UM47-1.2	P14K	Neutral	0.013
NOTCH3	Q9UM47-1.2	P14L	Neutral	0.224
NOTCH3	Q9UM47-1.2	P14M	Neutral	0.059
NOTCH3	Q9UM47-1.2	P14N	Neutral	0.066
NOTCH3	Q9UM47-1.2	P14Q	Neutral	0.014
NOTCH3	Q9UM47-1.2	P14R	Neutral	0.055
NOTCH3	Q9UM47-1.2	P14S	Neutral	0.015
NOTCH3	Q9UM47-1.2	P14T	Neutral	0.015
NOTCH3	Q9UM47-1.2	P14V	Neutral	0.064
NOTCH3	Q9UM47-1.2	P14W	Pathogenic	0.531
NOTCH3	Q9UM47-1.2	P14Y	Neutral	0.211
NOTCH3	Q9UM47-1.2	M15A	Neutral	0.27
NOTCH3	Q9UM47-1.2	M15C	Neutral	0.284
NOTCH3	Q9UM47-1.2	M15D	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	M15E	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	M15F	Neutral	0.088
NOTCH3	Q9UM47-1.2	M15G	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	M15H	Pathogenic	0.673
NOTCH3	Q9UM47-1.2	M15I	Neutral	0.022
NOTCH3	Q9UM47-1.2	M15K	Neutral	0.309
NOTCH3	Q9UM47-1.2	M15L	Neutral	0.005
NOTCH3	Q9UM47-1.2	M15N	Pathogenic	0.655
NOTCH3	Q9UM47-1.2	M15P	Pathogenic	0.648
NOTCH3	Q9UM47-1.2	M15Q	Neutral	0.089
NOTCH3	Q9UM47-1.2	M15R	Neutral	0.298
NOTCH3	Q9UM47-1.2	M15S	Neutral	0.276
NOTCH3	Q9UM47-1.2	M15T	Neutral	0.291
NOTCH3	Q9UM47-1.2	M15V	Neutral	0.02
NOTCH3	Q9UM47-1.2	M15W	Neutral	0.284
NOTCH3	Q9UM47-1.2	M15Y	Neutral	0.301
NOTCH3	Q9UM47-1.2	S16A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S16C	Neutral	0.022
NOTCH3	Q9UM47-1.2	S16D	Neutral	0.005
NOTCH3	Q9UM47-1.2	S16E	Neutral	0.004
NOTCH3	Q9UM47-1.2	S16F	Neutral	0.077
NOTCH3	Q9UM47-1.2	S16G	Neutral	0.005
NOTCH3	Q9UM47-1.2	S16H	Neutral	0.019
NOTCH3	Q9UM47-1.2	S16I	Neutral	0.08
NOTCH3	Q9UM47-1.2	S16K	Neutral	0.004
NOTCH3	Q9UM47-1.2	S16L	Neutral	0.08
NOTCH3	Q9UM47-1.2	S16M	Neutral	0.019
NOTCH3	Q9UM47-1.2	S16N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S16P	Neutral	0.021
NOTCH3	Q9UM47-1.2	S16Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	S16R	Neutral	0.017
NOTCH3	Q9UM47-1.2	S16T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S16V	Neutral	0.086
NOTCH3	Q9UM47-1.2	S16W	Neutral	0.256
NOTCH3	Q9UM47-1.2	S16Y	Neutral	0.075
NOTCH3	Q9UM47-1.2	P17A	Neutral	0.019
NOTCH3	Q9UM47-1.2	P17C	Neutral	0.304
NOTCH3	Q9UM47-1.2	P17D	Neutral	0.021
NOTCH3	Q9UM47-1.2	P17E	Neutral	0.02
NOTCH3	Q9UM47-1.2	P17F	Pathogenic	0.631
NOTCH3	Q9UM47-1.2	P17G	Neutral	0.077
NOTCH3	Q9UM47-1.2	P17H	Neutral	0.081
NOTCH3	Q9UM47-1.2	P17I	Neutral	0.282
NOTCH3	Q9UM47-1.2	P17K	Neutral	0.018
NOTCH3	Q9UM47-1.2	P17L	Neutral	0.281
NOTCH3	Q9UM47-1.2	P17M	Neutral	0.079
NOTCH3	Q9UM47-1.2	P17N	Neutral	0.088
NOTCH3	Q9UM47-1.2	P17Q	Neutral	0.019
NOTCH3	Q9UM47-1.2	P17R	Neutral	0.073
NOTCH3	Q9UM47-1.2	P17S	Neutral	0.02
NOTCH3	Q9UM47-1.2	P17T	Neutral	0.021
NOTCH3	Q9UM47-1.2	P17V	Neutral	0.084
NOTCH3	Q9UM47-1.2	P17W	Pathogenic	0.606
NOTCH3	Q9UM47-1.2	P17Y	Neutral	0.267
NOTCH3	Q9UM47-1.2	P18A	Neutral	0.02
NOTCH3	Q9UM47-1.2	P18C	Neutral	0.318
NOTCH3	Q9UM47-1.2	P18D	Neutral	0.022
NOTCH3	Q9UM47-1.2	P18E	Neutral	0.021
NOTCH3	Q9UM47-1.2	P18F	Pathogenic	0.646
NOTCH3	Q9UM47-1.2	P18G	Neutral	0.081
NOTCH3	Q9UM47-1.2	P18H	Neutral	0.085
NOTCH3	Q9UM47-1.2	P18I	Neutral	0.295
NOTCH3	Q9UM47-1.2	P18K	Neutral	0.019
NOTCH3	Q9UM47-1.2	P18L	Neutral	0.294
NOTCH3	Q9UM47-1.2	P18M	Neutral	0.084
NOTCH3	Q9UM47-1.2	P18N	Neutral	0.093
NOTCH3	Q9UM47-1.2	P18Q	Neutral	0.02
NOTCH3	Q9UM47-1.2	P18R	Neutral	0.078
NOTCH3	Q9UM47-1.2	P18S	Neutral	0.021
NOTCH3	Q9UM47-1.2	P18T	Neutral	0.022
NOTCH3	Q9UM47-1.2	P18V	Neutral	0.089
NOTCH3	Q9UM47-1.2	P18W	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	P18Y	Neutral	0.28
NOTCH3	Q9UM47-1.2	P19A	Neutral	0.029
NOTCH3	Q9UM47-1.2	P19C	Neutral	0.398
NOTCH3	Q9UM47-1.2	P19D	Neutral	0.032
NOTCH3	Q9UM47-1.2	P19E	Neutral	0.03
NOTCH3	Q9UM47-1.2	P19F	Pathogenic	0.722
NOTCH3	Q9UM47-1.2	P19G	Neutral	0.112
NOTCH3	Q9UM47-1.2	P19H	Neutral	0.117
NOTCH3	Q9UM47-1.2	P19I	Neutral	0.373
NOTCH3	Q9UM47-1.2	P19K	Neutral	0.027
NOTCH3	Q9UM47-1.2	P19L	Neutral	0.372
NOTCH3	Q9UM47-1.2	P19M	Neutral	0.115
NOTCH3	Q9UM47-1.2	P19N	Neutral	0.127
NOTCH3	Q9UM47-1.2	P19Q	Neutral	0.029
NOTCH3	Q9UM47-1.2	P19R	Neutral	0.107
NOTCH3	Q9UM47-1.2	P19S	Neutral	0.03
NOTCH3	Q9UM47-1.2	P19T	Neutral	0.031
NOTCH3	Q9UM47-1.2	P19V	Neutral	0.123
NOTCH3	Q9UM47-1.2	P19W	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	P19Y	Neutral	0.356
NOTCH3	Q9UM47-1.2	P20A	Neutral	0.013
NOTCH3	Q9UM47-1.2	P20C	Neutral	0.223
NOTCH3	Q9UM47-1.2	P20D	Neutral	0.014
NOTCH3	Q9UM47-1.2	P20E	Neutral	0.013
NOTCH3	Q9UM47-1.2	P20F	Pathogenic	0.53
NOTCH3	Q9UM47-1.2	P20G	Neutral	0.052
NOTCH3	Q9UM47-1.2	P20H	Neutral	0.055
NOTCH3	Q9UM47-1.2	P20I	Neutral	0.205
NOTCH3	Q9UM47-1.2	P20K	Neutral	0.012
NOTCH3	Q9UM47-1.2	P20L	Neutral	0.205
NOTCH3	Q9UM47-1.2	P20M	Neutral	0.053
NOTCH3	Q9UM47-1.2	P20N	Neutral	0.059
NOTCH3	Q9UM47-1.2	P20Q	Neutral	0.013
NOTCH3	Q9UM47-1.2	P20R	Neutral	0.049
NOTCH3	Q9UM47-1.2	P20S	Neutral	0.013
NOTCH3	Q9UM47-1.2	P20T	Neutral	0.014
NOTCH3	Q9UM47-1.2	P20V	Neutral	0.057
NOTCH3	Q9UM47-1.2	P20W	Pathogenic	0.503
NOTCH3	Q9UM47-1.2	P20Y	Neutral	0.194
NOTCH3	Q9UM47-1.2	P21A	Neutral	0.037
NOTCH3	Q9UM47-1.2	P21C	Neutral	0.463
NOTCH3	Q9UM47-1.2	P21D	Neutral	0.041
NOTCH3	Q9UM47-1.2	P21E	Neutral	0.038
NOTCH3	Q9UM47-1.2	P21F	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	P21G	Neutral	0.141
NOTCH3	Q9UM47-1.2	P21H	Neutral	0.147
NOTCH3	Q9UM47-1.2	P21I	Neutral	0.436
NOTCH3	Q9UM47-1.2	P21K	Neutral	0.035
NOTCH3	Q9UM47-1.2	P21L	Neutral	0.436
NOTCH3	Q9UM47-1.2	P21M	Neutral	0.144
NOTCH3	Q9UM47-1.2	P21N	Neutral	0.159
NOTCH3	Q9UM47-1.2	P21Q	Neutral	0.037
NOTCH3	Q9UM47-1.2	P21R	Neutral	0.135
NOTCH3	Q9UM47-1.2	P21S	Neutral	0.038
NOTCH3	Q9UM47-1.2	P21T	Neutral	0.04
NOTCH3	Q9UM47-1.2	P21V	Neutral	0.154
NOTCH3	Q9UM47-1.2	P21W	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	P21Y	Neutral	0.418
NOTCH3	Q9UM47-1.2	P22A	Neutral	0.013
NOTCH3	Q9UM47-1.2	P22C	Neutral	0.227
NOTCH3	Q9UM47-1.2	P22D	Neutral	0.014
NOTCH3	Q9UM47-1.2	P22E	Neutral	0.013
NOTCH3	Q9UM47-1.2	P22F	Pathogenic	0.534
NOTCH3	Q9UM47-1.2	P22G	Neutral	0.053
NOTCH3	Q9UM47-1.2	P22H	Neutral	0.056
NOTCH3	Q9UM47-1.2	P22I	Neutral	0.208
NOTCH3	Q9UM47-1.2	P22K	Neutral	0.012
NOTCH3	Q9UM47-1.2	P22L	Neutral	0.208
NOTCH3	Q9UM47-1.2	P22M	Neutral	0.054
NOTCH3	Q9UM47-1.2	P22N	Neutral	0.061
NOTCH3	Q9UM47-1.2	P22Q	Neutral	0.013
NOTCH3	Q9UM47-1.2	P22R	Neutral	0.05
NOTCH3	Q9UM47-1.2	P22S	Neutral	0.013
NOTCH3	Q9UM47-1.2	P22T	Neutral	0.014
NOTCH3	Q9UM47-1.2	P22V	Neutral	0.058
NOTCH3	Q9UM47-1.2	P22W	Pathogenic	0.508
NOTCH3	Q9UM47-1.2	P22Y	Neutral	0.196
NOTCH3	Q9UM47-1.2	P23A	Neutral	0.015
NOTCH3	Q9UM47-1.2	P23C	Neutral	0.257
NOTCH3	Q9UM47-1.2	P23D	Neutral	0.017
NOTCH3	Q9UM47-1.2	P23E	Neutral	0.016
NOTCH3	Q9UM47-1.2	P23F	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	P23G	Neutral	0.062
NOTCH3	Q9UM47-1.2	P23H	Neutral	0.065
NOTCH3	Q9UM47-1.2	P23I	Neutral	0.237
NOTCH3	Q9UM47-1.2	P23K	Neutral	0.014
NOTCH3	Q9UM47-1.2	P23L	Neutral	0.236
NOTCH3	Q9UM47-1.2	P23M	Neutral	0.063
NOTCH3	Q9UM47-1.2	P23N	Neutral	0.071
NOTCH3	Q9UM47-1.2	P23Q	Neutral	0.015
NOTCH3	Q9UM47-1.2	P23R	Neutral	0.059
NOTCH3	Q9UM47-1.2	P23S	Neutral	0.016
NOTCH3	Q9UM47-1.2	P23T	Neutral	0.016
NOTCH3	Q9UM47-1.2	P23V	Neutral	0.068
NOTCH3	Q9UM47-1.2	P23W	Pathogenic	0.549
NOTCH3	Q9UM47-1.2	P23Y	Neutral	0.224
NOTCH3	Q9UM47-1.2	V24A	Neutral	0.012
NOTCH3	Q9UM47-1.2	V24C	Neutral	0.054
NOTCH3	Q9UM47-1.2	V24D	Pathogenic	0.549
NOTCH3	Q9UM47-1.2	V24E	Neutral	0.217
NOTCH3	Q9UM47-1.2	V24F	Neutral	0.052
NOTCH3	Q9UM47-1.2	V24G	Pathogenic	0.506
NOTCH3	Q9UM47-1.2	V24H	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	V24I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V24K	Neutral	0.201
NOTCH3	Q9UM47-1.2	V24L	Neutral	0.003
NOTCH3	Q9UM47-1.2	V24M	Neutral	0.003
NOTCH3	Q9UM47-1.2	V24N	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	V24P	Neutral	0.208
NOTCH3	Q9UM47-1.2	V24Q	Neutral	0.213
NOTCH3	Q9UM47-1.2	V24R	Pathogenic	0.522
NOTCH3	Q9UM47-1.2	V24S	Neutral	0.199
NOTCH3	Q9UM47-1.2	V24T	Neutral	0.013
NOTCH3	Q9UM47-1.2	V24W	Pathogenic	0.505
NOTCH3	Q9UM47-1.2	V24Y	Neutral	0.051
NOTCH3	Q9UM47-1.2	R25A	Neutral	0.072
NOTCH3	Q9UM47-1.2	R25C	Pathogenic	0.635
NOTCH3	Q9UM47-1.2	R25D	Neutral	0.278
NOTCH3	Q9UM47-1.2	R25E	Neutral	0.02
NOTCH3	Q9UM47-1.2	R25F	Pathogenic	0.679
NOTCH3	Q9UM47-1.2	R25G	Neutral	0.247
NOTCH3	Q9UM47-1.2	R25H	Neutral	0.02
NOTCH3	Q9UM47-1.2	R25I	Pathogenic	0.67
NOTCH3	Q9UM47-1.2	R25K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R25L	Neutral	0.308
NOTCH3	Q9UM47-1.2	R25M	Neutral	0.089
NOTCH3	Q9UM47-1.2	R25N	Neutral	0.019
NOTCH3	Q9UM47-1.2	R25P	Neutral	0.279
NOTCH3	Q9UM47-1.2	R25Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	R25S	Neutral	0.073
NOTCH3	Q9UM47-1.2	R25T	Neutral	0.079
NOTCH3	Q9UM47-1.2	R25V	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	R25W	Pathogenic	0.679
NOTCH3	Q9UM47-1.2	R25Y	Neutral	0.321
NOTCH3	Q9UM47-1.2	A26C	Neutral	0.01
NOTCH3	Q9UM47-1.2	A26D	Neutral	0.169
NOTCH3	Q9UM47-1.2	A26E	Neutral	0.04
NOTCH3	Q9UM47-1.2	A26F	Neutral	0.147
NOTCH3	Q9UM47-1.2	A26G	Neutral	0.01
NOTCH3	Q9UM47-1.2	A26H	Neutral	0.154
NOTCH3	Q9UM47-1.2	A26I	Neutral	0.038
NOTCH3	Q9UM47-1.2	A26K	Neutral	0.036
NOTCH3	Q9UM47-1.2	A26L	Neutral	0.038
NOTCH3	Q9UM47-1.2	A26M	Neutral	0.038
NOTCH3	Q9UM47-1.2	A26N	Neutral	0.167
NOTCH3	Q9UM47-1.2	A26P	Neutral	0.043
NOTCH3	Q9UM47-1.2	A26Q	Neutral	0.039
NOTCH3	Q9UM47-1.2	A26R	Neutral	0.035
NOTCH3	Q9UM47-1.2	A26S	Neutral	0.002
NOTCH3	Q9UM47-1.2	A26T	Neutral	0.01
NOTCH3	Q9UM47-1.2	A26V	Neutral	0.009
NOTCH3	Q9UM47-1.2	A26W	Neutral	0.415
NOTCH3	Q9UM47-1.2	A26Y	Neutral	0.144
NOTCH3	Q9UM47-1.2	L27A	Neutral	0.053
NOTCH3	Q9UM47-1.2	L27C	Neutral	0.057
NOTCH3	Q9UM47-1.2	L27D	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	L27E	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	L27F	Neutral	0.014
NOTCH3	Q9UM47-1.2	L27G	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	L27H	Pathogenic	0.586
NOTCH3	Q9UM47-1.2	L27I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L27K	Neutral	0.235
NOTCH3	Q9UM47-1.2	L27M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L27N	Pathogenic	0.566
NOTCH3	Q9UM47-1.2	L27P	Pathogenic	0.558
NOTCH3	Q9UM47-1.2	L27Q	Neutral	0.235
NOTCH3	Q9UM47-1.2	L27R	Neutral	0.226
NOTCH3	Q9UM47-1.2	L27S	Neutral	0.207
NOTCH3	Q9UM47-1.2	L27T	Neutral	0.058
NOTCH3	Q9UM47-1.2	L27V	Neutral	0.003
NOTCH3	Q9UM47-1.2	L27W	Neutral	0.213
NOTCH3	Q9UM47-1.2	L27Y	Neutral	0.061
NOTCH3	Q9UM47-1.2	P28A	Neutral	0.094
NOTCH3	Q9UM47-1.2	P28C	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	P28D	Neutral	0.102
NOTCH3	Q9UM47-1.2	P28E	Neutral	0.096
NOTCH3	Q9UM47-1.2	P28F	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	P28G	Neutral	0.305
NOTCH3	Q9UM47-1.2	P28H	Neutral	0.316
NOTCH3	Q9UM47-1.2	P28I	Pathogenic	0.673
NOTCH3	Q9UM47-1.2	P28K	Neutral	0.087
NOTCH3	Q9UM47-1.2	P28L	Pathogenic	0.673
NOTCH3	Q9UM47-1.2	P28M	Neutral	0.311
NOTCH3	Q9UM47-1.2	P28N	Neutral	0.336
NOTCH3	Q9UM47-1.2	P28Q	Neutral	0.094
NOTCH3	Q9UM47-1.2	P28R	Neutral	0.293
NOTCH3	Q9UM47-1.2	P28S	Neutral	0.096
NOTCH3	Q9UM47-1.2	P28T	Neutral	0.1
NOTCH3	Q9UM47-1.2	P28V	Neutral	0.327
NOTCH3	Q9UM47-1.2	P28W	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	P28Y	Pathogenic	0.657
NOTCH3	Q9UM47-1.2	L29A	Neutral	0.2
NOTCH3	Q9UM47-1.2	L29C	Neutral	0.211
NOTCH3	Q9UM47-1.2	L29D	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	L29E	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	L29F	Neutral	0.061
NOTCH3	Q9UM47-1.2	L29G	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	L29H	Pathogenic	0.863
NOTCH3	Q9UM47-1.2	L29I	Neutral	0.003
NOTCH3	Q9UM47-1.2	L29K	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	L29M	Neutral	0.003
NOTCH3	Q9UM47-1.2	L29N	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	L29P	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	L29Q	Pathogenic	0.578
NOTCH3	Q9UM47-1.2	L29R	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	L29S	Pathogenic	0.539
NOTCH3	Q9UM47-1.2	L29T	Neutral	0.217
NOTCH3	Q9UM47-1.2	L29V	Neutral	0.014
NOTCH3	Q9UM47-1.2	L29W	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	L29Y	Neutral	0.225
NOTCH3	Q9UM47-1.2	L30A	Neutral	0.039
NOTCH3	Q9UM47-1.2	L30C	Neutral	0.041
NOTCH3	Q9UM47-1.2	L30D	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	L30E	Neutral	0.497
NOTCH3	Q9UM47-1.2	L30F	Neutral	0.01
NOTCH3	Q9UM47-1.2	L30G	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	L30H	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	L30I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L30K	Neutral	0.181
NOTCH3	Q9UM47-1.2	L30M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L30N	Neutral	0.484
NOTCH3	Q9UM47-1.2	L30P	Neutral	0.476
NOTCH3	Q9UM47-1.2	L30Q	Neutral	0.18
NOTCH3	Q9UM47-1.2	L30R	Neutral	0.174
NOTCH3	Q9UM47-1.2	L30S	Neutral	0.158
NOTCH3	Q9UM47-1.2	L30T	Neutral	0.043
NOTCH3	Q9UM47-1.2	L30V	Neutral	0.002
NOTCH3	Q9UM47-1.2	L30W	Neutral	0.163
NOTCH3	Q9UM47-1.2	L30Y	Neutral	0.045
NOTCH3	Q9UM47-1.2	L31A	Neutral	0.146
NOTCH3	Q9UM47-1.2	L31C	Neutral	0.154
NOTCH3	Q9UM47-1.2	L31D	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	L31E	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	L31F	Neutral	0.042
NOTCH3	Q9UM47-1.2	L31G	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	L31H	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	L31I	Neutral	0.002
NOTCH3	Q9UM47-1.2	L31K	Neutral	0.484
NOTCH3	Q9UM47-1.2	L31M	Neutral	0.002
NOTCH3	Q9UM47-1.2	L31N	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	L31P	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	L31Q	Neutral	0.483
NOTCH3	Q9UM47-1.2	L31R	Neutral	0.471
NOTCH3	Q9UM47-1.2	L31S	Neutral	0.443
NOTCH3	Q9UM47-1.2	L31T	Neutral	0.159
NOTCH3	Q9UM47-1.2	L31V	Neutral	0.009
NOTCH3	Q9UM47-1.2	L31W	Neutral	0.452
NOTCH3	Q9UM47-1.2	L31Y	Neutral	0.165
NOTCH3	Q9UM47-1.2	L32A	Neutral	0.106
NOTCH3	Q9UM47-1.2	L32C	Neutral	0.112
NOTCH3	Q9UM47-1.2	L32D	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	L32E	Pathogenic	0.744
NOTCH3	Q9UM47-1.2	L32F	Neutral	0.03
NOTCH3	Q9UM47-1.2	L32G	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	L32H	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	L32I	Neutral	0.002
NOTCH3	Q9UM47-1.2	L32K	Neutral	0.394
NOTCH3	Q9UM47-1.2	L32M	Neutral	0.002
NOTCH3	Q9UM47-1.2	L32N	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	L32P	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	L32Q	Neutral	0.393
NOTCH3	Q9UM47-1.2	L32R	Neutral	0.382
NOTCH3	Q9UM47-1.2	L32S	Neutral	0.356
NOTCH3	Q9UM47-1.2	L32T	Neutral	0.116
NOTCH3	Q9UM47-1.2	L32V	Neutral	0.007
NOTCH3	Q9UM47-1.2	L32W	Neutral	0.364
NOTCH3	Q9UM47-1.2	L32Y	Neutral	0.121
NOTCH3	Q9UM47-1.2	L33A	Neutral	0.104
NOTCH3	Q9UM47-1.2	L33C	Neutral	0.111
NOTCH3	Q9UM47-1.2	L33D	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	L33E	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	L33F	Neutral	0.029
NOTCH3	Q9UM47-1.2	L33G	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	L33H	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	L33I	Neutral	0.002
NOTCH3	Q9UM47-1.2	L33K	Neutral	0.39
NOTCH3	Q9UM47-1.2	L33M	Neutral	0.002
NOTCH3	Q9UM47-1.2	L33N	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	L33P	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	L33Q	Neutral	0.39
NOTCH3	Q9UM47-1.2	L33R	Neutral	0.378
NOTCH3	Q9UM47-1.2	L33S	Neutral	0.352
NOTCH3	Q9UM47-1.2	L33T	Neutral	0.114
NOTCH3	Q9UM47-1.2	L33V	Neutral	0.006
NOTCH3	Q9UM47-1.2	L33W	Neutral	0.361
NOTCH3	Q9UM47-1.2	L33Y	Neutral	0.119
NOTCH3	Q9UM47-1.2	A34C	Neutral	0.018
NOTCH3	Q9UM47-1.2	A34D	Neutral	0.273
NOTCH3	Q9UM47-1.2	A34E	Neutral	0.071
NOTCH3	Q9UM47-1.2	A34F	Neutral	0.241
NOTCH3	Q9UM47-1.2	A34G	Neutral	0.018
NOTCH3	Q9UM47-1.2	A34H	Neutral	0.251
NOTCH3	Q9UM47-1.2	A34I	Neutral	0.068
NOTCH3	Q9UM47-1.2	A34K	Neutral	0.065
NOTCH3	Q9UM47-1.2	A34L	Neutral	0.068
NOTCH3	Q9UM47-1.2	A34M	Neutral	0.068
NOTCH3	Q9UM47-1.2	A34N	Neutral	0.269
NOTCH3	Q9UM47-1.2	A34P	Neutral	0.076
NOTCH3	Q9UM47-1.2	A34Q	Neutral	0.07
NOTCH3	Q9UM47-1.2	A34R	Neutral	0.062
NOTCH3	Q9UM47-1.2	A34S	Neutral	0.004
NOTCH3	Q9UM47-1.2	A34T	Neutral	0.017
NOTCH3	Q9UM47-1.2	A34V	Neutral	0.017
NOTCH3	Q9UM47-1.2	A34W	Pathogenic	0.566
NOTCH3	Q9UM47-1.2	A34Y	Neutral	0.236
NOTCH3	Q9UM47-1.2	G35A	Neutral	0.005
NOTCH3	Q9UM47-1.2	G35C	Neutral	0.301
NOTCH3	Q9UM47-1.2	G35D	Neutral	0.02
NOTCH3	Q9UM47-1.2	G35E	Neutral	0.08
NOTCH3	Q9UM47-1.2	G35F	Neutral	0.264
NOTCH3	Q9UM47-1.2	G35H	Neutral	0.077
NOTCH3	Q9UM47-1.2	G35I	Pathogenic	0.631
NOTCH3	Q9UM47-1.2	G35K	Neutral	0.073
NOTCH3	Q9UM47-1.2	G35L	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	G35M	Neutral	0.272
NOTCH3	Q9UM47-1.2	G35N	Neutral	0.004
NOTCH3	Q9UM47-1.2	G35P	Neutral	0.085
NOTCH3	Q9UM47-1.2	G35Q	Neutral	0.078
NOTCH3	Q9UM47-1.2	G35R	Neutral	0.069
NOTCH3	Q9UM47-1.2	G35S	Neutral	0.005
NOTCH3	Q9UM47-1.2	G35T	Neutral	0.084
NOTCH3	Q9UM47-1.2	G35V	Neutral	0.286
NOTCH3	Q9UM47-1.2	G35W	Neutral	0.066
NOTCH3	Q9UM47-1.2	G35Y	Neutral	0.259
NOTCH3	Q9UM47-1.2	P36A	Neutral	0.019
NOTCH3	Q9UM47-1.2	P36C	Neutral	0.304
NOTCH3	Q9UM47-1.2	P36D	Neutral	0.021
NOTCH3	Q9UM47-1.2	P36E	Neutral	0.02
NOTCH3	Q9UM47-1.2	P36F	Pathogenic	0.631
NOTCH3	Q9UM47-1.2	P36G	Neutral	0.077
NOTCH3	Q9UM47-1.2	P36H	Neutral	0.081
NOTCH3	Q9UM47-1.2	P36I	Neutral	0.282
NOTCH3	Q9UM47-1.2	P36K	Neutral	0.018
NOTCH3	Q9UM47-1.2	P36L	Neutral	0.281
NOTCH3	Q9UM47-1.2	P36M	Neutral	0.079
NOTCH3	Q9UM47-1.2	P36N	Neutral	0.088
NOTCH3	Q9UM47-1.2	P36Q	Neutral	0.019
NOTCH3	Q9UM47-1.2	P36R	Neutral	0.073
NOTCH3	Q9UM47-1.2	P36S	Neutral	0.02
NOTCH3	Q9UM47-1.2	P36T	Neutral	0.021
NOTCH3	Q9UM47-1.2	P36V	Neutral	0.084
NOTCH3	Q9UM47-1.2	P36W	Pathogenic	0.606
NOTCH3	Q9UM47-1.2	P36Y	Neutral	0.267
NOTCH3	Q9UM47-1.2	G37A	Neutral	0.052
NOTCH3	Q9UM47-1.2	G37C	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	G37D	Neutral	0.185
NOTCH3	Q9UM47-1.2	G37E	Neutral	0.49
NOTCH3	Q9UM47-1.2	G37F	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	G37H	Neutral	0.48
NOTCH3	Q9UM47-1.2	G37I	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	G37K	Neutral	0.466
NOTCH3	Q9UM47-1.2	G37L	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	G37M	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	G37N	Neutral	0.046
NOTCH3	Q9UM47-1.2	G37P	Pathogenic	0.509
NOTCH3	Q9UM47-1.2	G37Q	Neutral	0.484
NOTCH3	Q9UM47-1.2	G37R	Neutral	0.453
NOTCH3	Q9UM47-1.2	G37S	Neutral	0.05
NOTCH3	Q9UM47-1.2	G37T	Pathogenic	0.505
NOTCH3	Q9UM47-1.2	G37V	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	G37W	Neutral	0.442
NOTCH3	Q9UM47-1.2	G37Y	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	A38C	Neutral	0.007
NOTCH3	Q9UM47-1.2	A38D	Neutral	0.129
NOTCH3	Q9UM47-1.2	A38E	Neutral	0.029
NOTCH3	Q9UM47-1.2	A38F	Neutral	0.112
NOTCH3	Q9UM47-1.2	A38G	Neutral	0.007
NOTCH3	Q9UM47-1.2	A38H	Neutral	0.117
NOTCH3	Q9UM47-1.2	A38I	Neutral	0.028
NOTCH3	Q9UM47-1.2	A38K	Neutral	0.027
NOTCH3	Q9UM47-1.2	A38L	Neutral	0.028
NOTCH3	Q9UM47-1.2	A38M	Neutral	0.028
NOTCH3	Q9UM47-1.2	A38N	Neutral	0.127
NOTCH3	Q9UM47-1.2	A38P	Neutral	0.032
NOTCH3	Q9UM47-1.2	A38Q	Neutral	0.029
NOTCH3	Q9UM47-1.2	A38R	Neutral	0.026
NOTCH3	Q9UM47-1.2	A38S	Neutral	0.002
NOTCH3	Q9UM47-1.2	A38T	Neutral	0.007
NOTCH3	Q9UM47-1.2	A38V	Neutral	0.007
NOTCH3	Q9UM47-1.2	A38W	Neutral	0.34
NOTCH3	Q9UM47-1.2	A38Y	Neutral	0.109
NOTCH3	Q9UM47-1.2	A39C	Neutral	0.017
NOTCH3	Q9UM47-1.2	A39D	Neutral	0.266
NOTCH3	Q9UM47-1.2	A39E	Neutral	0.069
NOTCH3	Q9UM47-1.2	A39F	Neutral	0.235
NOTCH3	Q9UM47-1.2	A39G	Neutral	0.017
NOTCH3	Q9UM47-1.2	A39H	Neutral	0.245
NOTCH3	Q9UM47-1.2	A39I	Neutral	0.066
NOTCH3	Q9UM47-1.2	A39K	Neutral	0.063
NOTCH3	Q9UM47-1.2	A39L	Neutral	0.066
NOTCH3	Q9UM47-1.2	A39M	Neutral	0.065
NOTCH3	Q9UM47-1.2	A39N	Neutral	0.262
NOTCH3	Q9UM47-1.2	A39P	Neutral	0.074
NOTCH3	Q9UM47-1.2	A39Q	Neutral	0.068
NOTCH3	Q9UM47-1.2	A39R	Neutral	0.06
NOTCH3	Q9UM47-1.2	A39S	Neutral	0.004
NOTCH3	Q9UM47-1.2	A39T	Neutral	0.017
NOTCH3	Q9UM47-1.2	A39V	Neutral	0.016
NOTCH3	Q9UM47-1.2	A39W	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	A39Y	Neutral	0.229
NOTCH3	Q9UM47-1.2	A40C	Neutral	0.007
NOTCH3	Q9UM47-1.2	A40D	Neutral	0.118
NOTCH3	Q9UM47-1.2	A40E	Neutral	0.027
NOTCH3	Q9UM47-1.2	A40F	Neutral	0.102
NOTCH3	Q9UM47-1.2	A40G	Neutral	0.006
NOTCH3	Q9UM47-1.2	A40H	Neutral	0.107
NOTCH3	Q9UM47-1.2	A40I	Neutral	0.025
NOTCH3	Q9UM47-1.2	A40K	Neutral	0.024
NOTCH3	Q9UM47-1.2	A40L	Neutral	0.025
NOTCH3	Q9UM47-1.2	A40M	Neutral	0.025
NOTCH3	Q9UM47-1.2	A40N	Neutral	0.116
NOTCH3	Q9UM47-1.2	A40P	Neutral	0.028
NOTCH3	Q9UM47-1.2	A40Q	Neutral	0.026
NOTCH3	Q9UM47-1.2	A40R	Neutral	0.023
NOTCH3	Q9UM47-1.2	A40S	Neutral	0.002
NOTCH3	Q9UM47-1.2	A40T	Neutral	0.006
NOTCH3	Q9UM47-1.2	A40V	Neutral	0.006
NOTCH3	Q9UM47-1.2	A40W	Neutral	0.317
NOTCH3	Q9UM47-1.2	A40Y	Neutral	0.099
NOTCH3	Q9UM47-1.2	P41A	Neutral	0.021
NOTCH3	Q9UM47-1.2	P41C	Neutral	0.324
NOTCH3	Q9UM47-1.2	P41D	Neutral	0.023
NOTCH3	Q9UM47-1.2	P41E	Neutral	0.022
NOTCH3	Q9UM47-1.2	P41F	Pathogenic	0.652
NOTCH3	Q9UM47-1.2	P41G	Neutral	0.084
NOTCH3	Q9UM47-1.2	P41H	Neutral	0.088
NOTCH3	Q9UM47-1.2	P41I	Neutral	0.301
NOTCH3	Q9UM47-1.2	P41K	Neutral	0.02
NOTCH3	Q9UM47-1.2	P41L	Neutral	0.3
NOTCH3	Q9UM47-1.2	P41M	Neutral	0.086
NOTCH3	Q9UM47-1.2	P41N	Neutral	0.095
NOTCH3	Q9UM47-1.2	P41Q	Neutral	0.021
NOTCH3	Q9UM47-1.2	P41R	Neutral	0.08
NOTCH3	Q9UM47-1.2	P41S	Neutral	0.022
NOTCH3	Q9UM47-1.2	P41T	Neutral	0.023
NOTCH3	Q9UM47-1.2	P41V	Neutral	0.092
NOTCH3	Q9UM47-1.2	P41W	Pathogenic	0.628
NOTCH3	Q9UM47-1.2	P41Y	Neutral	0.286
NOTCH3	Q9UM47-1.2	P42A	Neutral	0.008
NOTCH3	Q9UM47-1.2	P42C	Neutral	0.157
NOTCH3	Q9UM47-1.2	P42D	Neutral	0.009
NOTCH3	Q9UM47-1.2	P42E	Neutral	0.008
NOTCH3	Q9UM47-1.2	P42F	Neutral	0.422
NOTCH3	Q9UM47-1.2	P42G	Neutral	0.034
NOTCH3	Q9UM47-1.2	P42H	Neutral	0.036
NOTCH3	Q9UM47-1.2	P42I	Neutral	0.143
NOTCH3	Q9UM47-1.2	P42K	Neutral	0.008
NOTCH3	Q9UM47-1.2	P42L	Neutral	0.143
NOTCH3	Q9UM47-1.2	P42M	Neutral	0.035
NOTCH3	Q9UM47-1.2	P42N	Neutral	0.039
NOTCH3	Q9UM47-1.2	P42Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	P42R	Neutral	0.033
NOTCH3	Q9UM47-1.2	P42S	Neutral	0.009
NOTCH3	Q9UM47-1.2	P42T	Neutral	0.009
NOTCH3	Q9UM47-1.2	P42V	Neutral	0.038
NOTCH3	Q9UM47-1.2	P42W	Neutral	0.396
NOTCH3	Q9UM47-1.2	P42Y	Neutral	0.135
NOTCH3	Q9UM47-1.2	C43A	Neutral	0.199
NOTCH3	Q9UM47-1.2	C43D	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	C43E	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C43F	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	C43G	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	C43H	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	C43I	Pathogenic	0.513
NOTCH3	Q9UM47-1.2	C43K	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	C43L	Pathogenic	0.513
NOTCH3	Q9UM47-1.2	C43M	Pathogenic	0.512
NOTCH3	Q9UM47-1.2	C43N	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	C43P	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	C43Q	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	C43R	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	C43S	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	C43T	Pathogenic	0.543
NOTCH3	Q9UM47-1.2	C43V	Pathogenic	0.53
NOTCH3	Q9UM47-1.2	C43W	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	C43Y	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	L44A	Neutral	0.015
NOTCH3	Q9UM47-1.2	L44C	Neutral	0.016
NOTCH3	Q9UM47-1.2	L44D	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	L44E	Neutral	0.27
NOTCH3	Q9UM47-1.2	L44F	Neutral	0.004
NOTCH3	Q9UM47-1.2	L44G	Pathogenic	0.569
NOTCH3	Q9UM47-1.2	L44H	Neutral	0.275
NOTCH3	Q9UM47-1.2	L44I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L44K	Neutral	0.076
NOTCH3	Q9UM47-1.2	L44M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L44N	Neutral	0.26
NOTCH3	Q9UM47-1.2	L44P	Neutral	0.253
NOTCH3	Q9UM47-1.2	L44Q	Neutral	0.076
NOTCH3	Q9UM47-1.2	L44R	Neutral	0.073
NOTCH3	Q9UM47-1.2	L44S	Neutral	0.066
NOTCH3	Q9UM47-1.2	L44T	Neutral	0.016
NOTCH3	Q9UM47-1.2	L44V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L44W	Neutral	0.068
NOTCH3	Q9UM47-1.2	L44Y	Neutral	0.017
NOTCH3	Q9UM47-1.2	D45A	Neutral	0.257
NOTCH3	Q9UM47-1.2	D45C	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	D45E	Neutral	0.001
NOTCH3	Q9UM47-1.2	D45F	Pathogenic	0.596
NOTCH3	Q9UM47-1.2	D45G	Neutral	0.066
NOTCH3	Q9UM47-1.2	D45H	Neutral	0.07
NOTCH3	Q9UM47-1.2	D45I	Pathogenic	0.606
NOTCH3	Q9UM47-1.2	D45K	Neutral	0.065
NOTCH3	Q9UM47-1.2	D45L	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	D45M	Pathogenic	0.605
NOTCH3	Q9UM47-1.2	D45N	Neutral	0.004
NOTCH3	Q9UM47-1.2	D45P	Neutral	0.077
NOTCH3	Q9UM47-1.2	D45Q	Neutral	0.016
NOTCH3	Q9UM47-1.2	D45R	Neutral	0.232
NOTCH3	Q9UM47-1.2	D45S	Neutral	0.017
NOTCH3	Q9UM47-1.2	D45T	Neutral	0.076
NOTCH3	Q9UM47-1.2	D45V	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	D45W	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	D45Y	Pathogenic	0.588
NOTCH3	Q9UM47-1.2	G46A	Neutral	0.004
NOTCH3	Q9UM47-1.2	G46C	Neutral	0.274
NOTCH3	Q9UM47-1.2	G46D	Neutral	0.018
NOTCH3	Q9UM47-1.2	G46E	Neutral	0.07
NOTCH3	Q9UM47-1.2	G46F	Neutral	0.239
NOTCH3	Q9UM47-1.2	G46H	Neutral	0.068
NOTCH3	Q9UM47-1.2	G46I	Pathogenic	0.599
NOTCH3	Q9UM47-1.2	G46K	Neutral	0.064
NOTCH3	Q9UM47-1.2	G46L	Pathogenic	0.599
NOTCH3	Q9UM47-1.2	G46M	Neutral	0.246
NOTCH3	Q9UM47-1.2	G46N	Neutral	0.004
NOTCH3	Q9UM47-1.2	G46P	Neutral	0.075
NOTCH3	Q9UM47-1.2	G46Q	Neutral	0.069
NOTCH3	Q9UM47-1.2	G46R	Neutral	0.061
NOTCH3	Q9UM47-1.2	G46S	Neutral	0.004
NOTCH3	Q9UM47-1.2	G46T	Neutral	0.074
NOTCH3	Q9UM47-1.2	G46V	Neutral	0.26
NOTCH3	Q9UM47-1.2	G46W	Neutral	0.059
NOTCH3	Q9UM47-1.2	G46Y	Neutral	0.234
NOTCH3	Q9UM47-1.2	S47A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S47C	Neutral	0.021
NOTCH3	Q9UM47-1.2	S47D	Neutral	0.004
NOTCH3	Q9UM47-1.2	S47E	Neutral	0.004
NOTCH3	Q9UM47-1.2	S47F	Neutral	0.074
NOTCH3	Q9UM47-1.2	S47G	Neutral	0.004
NOTCH3	Q9UM47-1.2	S47H	Neutral	0.018
NOTCH3	Q9UM47-1.2	S47I	Neutral	0.077
NOTCH3	Q9UM47-1.2	S47K	Neutral	0.004
NOTCH3	Q9UM47-1.2	S47L	Neutral	0.077
NOTCH3	Q9UM47-1.2	S47M	Neutral	0.018
NOTCH3	Q9UM47-1.2	S47N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S47P	Neutral	0.02
NOTCH3	Q9UM47-1.2	S47Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	S47R	Neutral	0.016
NOTCH3	Q9UM47-1.2	S47T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S47V	Neutral	0.082
NOTCH3	Q9UM47-1.2	S47W	Neutral	0.246
NOTCH3	Q9UM47-1.2	S47Y	Neutral	0.072
NOTCH3	Q9UM47-1.2	P48A	Neutral	0.092
NOTCH3	Q9UM47-1.2	P48C	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	P48D	Neutral	0.1
NOTCH3	Q9UM47-1.2	P48E	Neutral	0.094
NOTCH3	Q9UM47-1.2	P48F	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	P48G	Neutral	0.3
NOTCH3	Q9UM47-1.2	P48H	Neutral	0.311
NOTCH3	Q9UM47-1.2	P48I	Pathogenic	0.668
NOTCH3	Q9UM47-1.2	P48K	Neutral	0.086
NOTCH3	Q9UM47-1.2	P48L	Pathogenic	0.668
NOTCH3	Q9UM47-1.2	P48M	Neutral	0.306
NOTCH3	Q9UM47-1.2	P48N	Neutral	0.331
NOTCH3	Q9UM47-1.2	P48Q	Neutral	0.092
NOTCH3	Q9UM47-1.2	P48R	Neutral	0.289
NOTCH3	Q9UM47-1.2	P48S	Neutral	0.094
NOTCH3	Q9UM47-1.2	P48T	Neutral	0.098
NOTCH3	Q9UM47-1.2	P48V	Neutral	0.322
NOTCH3	Q9UM47-1.2	P48W	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	P48Y	Pathogenic	0.652
NOTCH3	Q9UM47-1.2	C49A	Neutral	0.207
NOTCH3	Q9UM47-1.2	C49D	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	C49E	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C49F	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	C49G	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	C49H	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	C49I	Pathogenic	0.525
NOTCH3	Q9UM47-1.2	C49K	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	C49L	Pathogenic	0.525
NOTCH3	Q9UM47-1.2	C49M	Pathogenic	0.524
NOTCH3	Q9UM47-1.2	C49N	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	C49P	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	C49Q	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	C49R	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	C49S	Pathogenic	0.55
NOTCH3	Q9UM47-1.2	C49T	Pathogenic	0.555
NOTCH3	Q9UM47-1.2	C49V	Pathogenic	0.542
NOTCH3	Q9UM47-1.2	C49W	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C49Y	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	A50C	Neutral	0.001
NOTCH3	Q9UM47-1.2	A50D	Neutral	0.022
NOTCH3	Q9UM47-1.2	A50E	Neutral	0.005
NOTCH3	Q9UM47-1.2	A50F	Neutral	0.019
NOTCH3	Q9UM47-1.2	A50G	Neutral	0.001
NOTCH3	Q9UM47-1.2	A50H	Neutral	0.02
NOTCH3	Q9UM47-1.2	A50I	Neutral	0.004
NOTCH3	Q9UM47-1.2	A50K	Neutral	0.004
NOTCH3	Q9UM47-1.2	A50L	Neutral	0.004
NOTCH3	Q9UM47-1.2	A50M	Neutral	0.004
NOTCH3	Q9UM47-1.2	A50N	Neutral	0.022
NOTCH3	Q9UM47-1.2	A50P	Neutral	0.005
NOTCH3	Q9UM47-1.2	A50Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	A50R	Neutral	0.004
NOTCH3	Q9UM47-1.2	A50S	Neutral	0.0
NOTCH3	Q9UM47-1.2	A50T	Neutral	0.001
NOTCH3	Q9UM47-1.2	A50V	Neutral	0.001
NOTCH3	Q9UM47-1.2	A50W	Neutral	0.073
NOTCH3	Q9UM47-1.2	A50Y	Neutral	0.018
NOTCH3	Q9UM47-1.2	N51A	Pathogenic	0.785
NOTCH3	Q9UM47-1.2	N51C	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	N51D	Neutral	0.04
NOTCH3	Q9UM47-1.2	N51E	Neutral	0.157
NOTCH3	Q9UM47-1.2	N51F	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	N51G	Neutral	0.14
NOTCH3	Q9UM47-1.2	N51H	Neutral	0.038
NOTCH3	Q9UM47-1.2	N51I	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	N51K	Neutral	0.144
NOTCH3	Q9UM47-1.2	N51L	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	N51M	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	N51P	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	N51Q	Neutral	0.155
NOTCH3	Q9UM47-1.2	N51R	Neutral	0.138
NOTCH3	Q9UM47-1.2	N51S	Neutral	0.038
NOTCH3	Q9UM47-1.2	N51T	Neutral	0.163
NOTCH3	Q9UM47-1.2	N51V	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	N51W	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N51Y	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	G52A	Neutral	0.02
NOTCH3	Q9UM47-1.2	G52C	Pathogenic	0.637
NOTCH3	Q9UM47-1.2	G52D	Neutral	0.077
NOTCH3	Q9UM47-1.2	G52E	Neutral	0.26
NOTCH3	Q9UM47-1.2	G52F	Pathogenic	0.594
NOTCH3	Q9UM47-1.2	G52H	Neutral	0.253
NOTCH3	Q9UM47-1.2	G52I	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	G52K	Neutral	0.242
NOTCH3	Q9UM47-1.2	G52L	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	G52M	Pathogenic	0.603
NOTCH3	Q9UM47-1.2	G52N	Neutral	0.018
NOTCH3	Q9UM47-1.2	G52P	Neutral	0.275
NOTCH3	Q9UM47-1.2	G52Q	Neutral	0.256
NOTCH3	Q9UM47-1.2	G52R	Neutral	0.233
NOTCH3	Q9UM47-1.2	G52S	Neutral	0.019
NOTCH3	Q9UM47-1.2	G52T	Neutral	0.272
NOTCH3	Q9UM47-1.2	G52V	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	G52W	Neutral	0.225
NOTCH3	Q9UM47-1.2	G52Y	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	G53A	Neutral	0.07
NOTCH3	Q9UM47-1.2	G53C	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	G53D	Neutral	0.238
NOTCH3	Q9UM47-1.2	G53E	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	G53F	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G53H	Pathogenic	0.56
NOTCH3	Q9UM47-1.2	G53I	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G53K	Pathogenic	0.546
NOTCH3	Q9UM47-1.2	G53L	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G53M	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	G53N	Neutral	0.063
NOTCH3	Q9UM47-1.2	G53P	Pathogenic	0.588
NOTCH3	Q9UM47-1.2	G53Q	Pathogenic	0.564
NOTCH3	Q9UM47-1.2	G53R	Pathogenic	0.534
NOTCH3	Q9UM47-1.2	G53S	Neutral	0.068
NOTCH3	Q9UM47-1.2	G53T	Pathogenic	0.584
NOTCH3	Q9UM47-1.2	G53V	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	G53W	Pathogenic	0.522
NOTCH3	Q9UM47-1.2	G53Y	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	R54A	Neutral	0.053
NOTCH3	Q9UM47-1.2	R54C	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	R54D	Neutral	0.217
NOTCH3	Q9UM47-1.2	R54E	Neutral	0.014
NOTCH3	Q9UM47-1.2	R54F	Pathogenic	0.604
NOTCH3	Q9UM47-1.2	R54G	Neutral	0.191
NOTCH3	Q9UM47-1.2	R54H	Neutral	0.015
NOTCH3	Q9UM47-1.2	R54I	Pathogenic	0.594
NOTCH3	Q9UM47-1.2	R54K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R54L	Neutral	0.243
NOTCH3	Q9UM47-1.2	R54M	Neutral	0.066
NOTCH3	Q9UM47-1.2	R54N	Neutral	0.013
NOTCH3	Q9UM47-1.2	R54P	Neutral	0.219
NOTCH3	Q9UM47-1.2	R54Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R54S	Neutral	0.054
NOTCH3	Q9UM47-1.2	R54T	Neutral	0.058
NOTCH3	Q9UM47-1.2	R54V	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	R54W	Pathogenic	0.604
NOTCH3	Q9UM47-1.2	R54Y	Neutral	0.254
NOTCH3	Q9UM47-1.2	C55A	Neutral	0.216
NOTCH3	Q9UM47-1.2	C55D	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	C55E	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	C55F	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C55G	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	C55H	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	C55I	Pathogenic	0.539
NOTCH3	Q9UM47-1.2	C55K	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	C55L	Pathogenic	0.539
NOTCH3	Q9UM47-1.2	C55M	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	C55N	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	C55P	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	C55Q	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	C55R	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	C55S	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	C55T	Pathogenic	0.568
NOTCH3	Q9UM47-1.2	C55V	Pathogenic	0.556
NOTCH3	Q9UM47-1.2	C55W	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	C55Y	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	T56A	Neutral	0.003
NOTCH3	Q9UM47-1.2	T56C	Neutral	0.017
NOTCH3	Q9UM47-1.2	T56D	Neutral	0.017
NOTCH3	Q9UM47-1.2	T56E	Neutral	0.016
NOTCH3	Q9UM47-1.2	T56F	Neutral	0.063
NOTCH3	Q9UM47-1.2	T56G	Neutral	0.062
NOTCH3	Q9UM47-1.2	T56H	Neutral	0.066
NOTCH3	Q9UM47-1.2	T56I	Neutral	0.015
NOTCH3	Q9UM47-1.2	T56K	Neutral	0.015
NOTCH3	Q9UM47-1.2	T56L	Neutral	0.015
NOTCH3	Q9UM47-1.2	T56M	Neutral	0.015
NOTCH3	Q9UM47-1.2	T56N	Neutral	0.004
NOTCH3	Q9UM47-1.2	T56P	Neutral	0.017
NOTCH3	Q9UM47-1.2	T56Q	Neutral	0.016
NOTCH3	Q9UM47-1.2	T56R	Neutral	0.014
NOTCH3	Q9UM47-1.2	T56S	Neutral	0.001
NOTCH3	Q9UM47-1.2	T56V	Neutral	0.004
NOTCH3	Q9UM47-1.2	T56W	Neutral	0.057
NOTCH3	Q9UM47-1.2	T56Y	Neutral	0.061
NOTCH3	Q9UM47-1.2	Q57A	Neutral	0.015
NOTCH3	Q9UM47-1.2	Q57C	Neutral	0.258
NOTCH3	Q9UM47-1.2	Q57D	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q57E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q57F	Neutral	0.265
NOTCH3	Q9UM47-1.2	Q57G	Neutral	0.062
NOTCH3	Q9UM47-1.2	Q57H	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q57I	Neutral	0.273
NOTCH3	Q9UM47-1.2	Q57K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q57L	Neutral	0.076
NOTCH3	Q9UM47-1.2	Q57M	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q57N	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q57P	Neutral	0.017
NOTCH3	Q9UM47-1.2	Q57R	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q57S	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q57T	Neutral	0.017
NOTCH3	Q9UM47-1.2	Q57V	Neutral	0.076
NOTCH3	Q9UM47-1.2	Q57W	Neutral	0.067
NOTCH3	Q9UM47-1.2	Q57Y	Neutral	0.017
NOTCH3	Q9UM47-1.2	L58A	Neutral	0.006
NOTCH3	Q9UM47-1.2	L58C	Neutral	0.006
NOTCH3	Q9UM47-1.2	L58D	Neutral	0.384
NOTCH3	Q9UM47-1.2	L58E	Neutral	0.128
NOTCH3	Q9UM47-1.2	L58F	Neutral	0.002
NOTCH3	Q9UM47-1.2	L58G	Neutral	0.344
NOTCH3	Q9UM47-1.2	L58H	Neutral	0.131
NOTCH3	Q9UM47-1.2	L58I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L58K	Neutral	0.032
NOTCH3	Q9UM47-1.2	L58M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L58N	Neutral	0.122
NOTCH3	Q9UM47-1.2	L58P	Neutral	0.119
NOTCH3	Q9UM47-1.2	L58Q	Neutral	0.032
NOTCH3	Q9UM47-1.2	L58R	Neutral	0.03
NOTCH3	Q9UM47-1.2	L58S	Neutral	0.027
NOTCH3	Q9UM47-1.2	L58T	Neutral	0.007
NOTCH3	Q9UM47-1.2	L58V	Neutral	0.0
NOTCH3	Q9UM47-1.2	L58W	Neutral	0.028
NOTCH3	Q9UM47-1.2	L58Y	Neutral	0.007
NOTCH3	Q9UM47-1.2	P59A	Neutral	0.019
NOTCH3	Q9UM47-1.2	P59C	Neutral	0.296
NOTCH3	Q9UM47-1.2	P59D	Neutral	0.02
NOTCH3	Q9UM47-1.2	P59E	Neutral	0.019
NOTCH3	Q9UM47-1.2	P59F	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	P59G	Neutral	0.074
NOTCH3	Q9UM47-1.2	P59H	Neutral	0.078
NOTCH3	Q9UM47-1.2	P59I	Neutral	0.274
NOTCH3	Q9UM47-1.2	P59K	Neutral	0.017
NOTCH3	Q9UM47-1.2	P59L	Neutral	0.274
NOTCH3	Q9UM47-1.2	P59M	Neutral	0.076
NOTCH3	Q9UM47-1.2	P59N	Neutral	0.085
NOTCH3	Q9UM47-1.2	P59Q	Neutral	0.019
NOTCH3	Q9UM47-1.2	P59R	Neutral	0.071
NOTCH3	Q9UM47-1.2	P59S	Neutral	0.019
NOTCH3	Q9UM47-1.2	P59T	Neutral	0.02
NOTCH3	Q9UM47-1.2	P59V	Neutral	0.082
NOTCH3	Q9UM47-1.2	P59W	Pathogenic	0.598
NOTCH3	Q9UM47-1.2	P59Y	Neutral	0.26
NOTCH3	Q9UM47-1.2	S60A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S60C	Neutral	0.017
NOTCH3	Q9UM47-1.2	S60D	Neutral	0.004
NOTCH3	Q9UM47-1.2	S60E	Neutral	0.003
NOTCH3	Q9UM47-1.2	S60F	Neutral	0.061
NOTCH3	Q9UM47-1.2	S60G	Neutral	0.004
NOTCH3	Q9UM47-1.2	S60H	Neutral	0.015
NOTCH3	Q9UM47-1.2	S60I	Neutral	0.063
NOTCH3	Q9UM47-1.2	S60K	Neutral	0.003
NOTCH3	Q9UM47-1.2	S60L	Neutral	0.063
NOTCH3	Q9UM47-1.2	S60M	Neutral	0.015
NOTCH3	Q9UM47-1.2	S60N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S60P	Neutral	0.016
NOTCH3	Q9UM47-1.2	S60Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	S60R	Neutral	0.013
NOTCH3	Q9UM47-1.2	S60T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S60V	Neutral	0.067
NOTCH3	Q9UM47-1.2	S60W	Neutral	0.209
NOTCH3	Q9UM47-1.2	S60Y	Neutral	0.059
NOTCH3	Q9UM47-1.2	R61A	Neutral	0.041
NOTCH3	Q9UM47-1.2	R61C	Neutral	0.491
NOTCH3	Q9UM47-1.2	R61D	Neutral	0.175
NOTCH3	Q9UM47-1.2	R61E	Neutral	0.011
NOTCH3	Q9UM47-1.2	R61F	Pathogenic	0.539
NOTCH3	Q9UM47-1.2	R61G	Neutral	0.153
NOTCH3	Q9UM47-1.2	R61H	Neutral	0.011
NOTCH3	Q9UM47-1.2	R61I	Pathogenic	0.529
NOTCH3	Q9UM47-1.2	R61K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R61L	Neutral	0.198
NOTCH3	Q9UM47-1.2	R61M	Neutral	0.051
NOTCH3	Q9UM47-1.2	R61N	Neutral	0.01
NOTCH3	Q9UM47-1.2	R61P	Neutral	0.177
NOTCH3	Q9UM47-1.2	R61Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	R61S	Neutral	0.042
NOTCH3	Q9UM47-1.2	R61T	Neutral	0.045
NOTCH3	Q9UM47-1.2	R61V	Pathogenic	0.509
NOTCH3	Q9UM47-1.2	R61W	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	R61Y	Neutral	0.207
NOTCH3	Q9UM47-1.2	E62A	Neutral	0.025
NOTCH3	Q9UM47-1.2	E62C	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	E62D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E62F	Neutral	0.365
NOTCH3	Q9UM47-1.2	E62G	Neutral	0.098
NOTCH3	Q9UM47-1.2	E62H	Neutral	0.006
NOTCH3	Q9UM47-1.2	E62I	Neutral	0.375
NOTCH3	Q9UM47-1.2	E62K	Neutral	0.001
NOTCH3	Q9UM47-1.2	E62L	Neutral	0.375
NOTCH3	Q9UM47-1.2	E62M	Neutral	0.116
NOTCH3	Q9UM47-1.2	E62N	Neutral	0.006
NOTCH3	Q9UM47-1.2	E62P	Neutral	0.028
NOTCH3	Q9UM47-1.2	E62Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E62R	Neutral	0.006
NOTCH3	Q9UM47-1.2	E62S	Neutral	0.006
NOTCH3	Q9UM47-1.2	E62T	Neutral	0.028
NOTCH3	Q9UM47-1.2	E62V	Neutral	0.12
NOTCH3	Q9UM47-1.2	E62W	Neutral	0.341
NOTCH3	Q9UM47-1.2	E62Y	Neutral	0.109
NOTCH3	Q9UM47-1.2	A63C	Neutral	0.004
NOTCH3	Q9UM47-1.2	A63D	Neutral	0.083
NOTCH3	Q9UM47-1.2	A63E	Neutral	0.018
NOTCH3	Q9UM47-1.2	A63F	Neutral	0.071
NOTCH3	Q9UM47-1.2	A63G	Neutral	0.004
NOTCH3	Q9UM47-1.2	A63H	Neutral	0.074
NOTCH3	Q9UM47-1.2	A63I	Neutral	0.017
NOTCH3	Q9UM47-1.2	A63K	Neutral	0.016
NOTCH3	Q9UM47-1.2	A63L	Neutral	0.017
NOTCH3	Q9UM47-1.2	A63M	Neutral	0.017
NOTCH3	Q9UM47-1.2	A63N	Neutral	0.081
NOTCH3	Q9UM47-1.2	A63P	Neutral	0.019
NOTCH3	Q9UM47-1.2	A63Q	Neutral	0.018
NOTCH3	Q9UM47-1.2	A63R	Neutral	0.016
NOTCH3	Q9UM47-1.2	A63S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A63T	Neutral	0.004
NOTCH3	Q9UM47-1.2	A63V	Neutral	0.004
NOTCH3	Q9UM47-1.2	A63W	Neutral	0.238
NOTCH3	Q9UM47-1.2	A63Y	Neutral	0.069
NOTCH3	Q9UM47-1.2	A64C	Neutral	0.008
NOTCH3	Q9UM47-1.2	A64D	Neutral	0.134
NOTCH3	Q9UM47-1.2	A64E	Neutral	0.031
NOTCH3	Q9UM47-1.2	A64F	Neutral	0.115
NOTCH3	Q9UM47-1.2	A64G	Neutral	0.007
NOTCH3	Q9UM47-1.2	A64H	Neutral	0.121
NOTCH3	Q9UM47-1.2	A64I	Neutral	0.029
NOTCH3	Q9UM47-1.2	A64K	Neutral	0.028
NOTCH3	Q9UM47-1.2	A64L	Neutral	0.029
NOTCH3	Q9UM47-1.2	A64M	Neutral	0.029
NOTCH3	Q9UM47-1.2	A64N	Neutral	0.131
NOTCH3	Q9UM47-1.2	A64P	Neutral	0.033
NOTCH3	Q9UM47-1.2	A64Q	Neutral	0.03
NOTCH3	Q9UM47-1.2	A64R	Neutral	0.027
NOTCH3	Q9UM47-1.2	A64S	Neutral	0.002
NOTCH3	Q9UM47-1.2	A64T	Neutral	0.007
NOTCH3	Q9UM47-1.2	A64V	Neutral	0.007
NOTCH3	Q9UM47-1.2	A64W	Neutral	0.349
NOTCH3	Q9UM47-1.2	A64Y	Neutral	0.112
NOTCH3	Q9UM47-1.2	C65A	Neutral	0.245
NOTCH3	Q9UM47-1.2	C65D	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	C65E	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	C65F	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	C65G	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	C65H	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	C65I	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	C65K	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	C65L	Pathogenic	0.578
NOTCH3	Q9UM47-1.2	C65M	Pathogenic	0.578
NOTCH3	Q9UM47-1.2	C65N	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	C65P	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	C65Q	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	C65R	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	C65S	Pathogenic	0.602
NOTCH3	Q9UM47-1.2	C65T	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	C65V	Pathogenic	0.595
NOTCH3	Q9UM47-1.2	C65W	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	C65Y	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	L66A	Neutral	0.009
NOTCH3	Q9UM47-1.2	L66C	Neutral	0.01
NOTCH3	Q9UM47-1.2	L66D	Neutral	0.498
NOTCH3	Q9UM47-1.2	L66E	Neutral	0.189
NOTCH3	Q9UM47-1.2	L66F	Neutral	0.002
NOTCH3	Q9UM47-1.2	L66G	Neutral	0.455
NOTCH3	Q9UM47-1.2	L66H	Neutral	0.194
NOTCH3	Q9UM47-1.2	L66I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L66K	Neutral	0.05
NOTCH3	Q9UM47-1.2	L66M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L66N	Neutral	0.182
NOTCH3	Q9UM47-1.2	L66P	Neutral	0.177
NOTCH3	Q9UM47-1.2	L66Q	Neutral	0.049
NOTCH3	Q9UM47-1.2	L66R	Neutral	0.047
NOTCH3	Q9UM47-1.2	L66S	Neutral	0.042
NOTCH3	Q9UM47-1.2	L66T	Neutral	0.01
NOTCH3	Q9UM47-1.2	L66V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L66W	Neutral	0.044
NOTCH3	Q9UM47-1.2	L66Y	Neutral	0.011
NOTCH3	Q9UM47-1.2	C67A	Neutral	0.41
NOTCH3	Q9UM47-1.2	C67D	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C67E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C67F	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	C67G	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	C67H	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	C67I	Pathogenic	0.747
NOTCH3	Q9UM47-1.2	C67K	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	C67L	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	C67M	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	C67N	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C67P	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C67Q	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C67R	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	C67S	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	C67T	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	C67V	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	C67W	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	C67Y	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	P68A	Neutral	0.032
NOTCH3	Q9UM47-1.2	P68C	Neutral	0.428
NOTCH3	Q9UM47-1.2	P68D	Neutral	0.036
NOTCH3	Q9UM47-1.2	P68E	Neutral	0.033
NOTCH3	Q9UM47-1.2	P68F	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	P68G	Neutral	0.125
NOTCH3	Q9UM47-1.2	P68H	Neutral	0.131
NOTCH3	Q9UM47-1.2	P68I	Neutral	0.402
NOTCH3	Q9UM47-1.2	P68K	Neutral	0.03
NOTCH3	Q9UM47-1.2	P68L	Neutral	0.401
NOTCH3	Q9UM47-1.2	P68M	Neutral	0.128
NOTCH3	Q9UM47-1.2	P68N	Neutral	0.141
NOTCH3	Q9UM47-1.2	P68Q	Neutral	0.033
NOTCH3	Q9UM47-1.2	P68R	Neutral	0.119
NOTCH3	Q9UM47-1.2	P68S	Neutral	0.033
NOTCH3	Q9UM47-1.2	P68T	Neutral	0.035
NOTCH3	Q9UM47-1.2	P68V	Neutral	0.136
NOTCH3	Q9UM47-1.2	P68W	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	P68Y	Neutral	0.384
NOTCH3	Q9UM47-1.2	P69A	Neutral	0.023
NOTCH3	Q9UM47-1.2	P69C	Neutral	0.344
NOTCH3	Q9UM47-1.2	P69D	Neutral	0.025
NOTCH3	Q9UM47-1.2	P69E	Neutral	0.024
NOTCH3	Q9UM47-1.2	P69F	Pathogenic	0.672
NOTCH3	Q9UM47-1.2	P69G	Neutral	0.091
NOTCH3	Q9UM47-1.2	P69H	Neutral	0.095
NOTCH3	Q9UM47-1.2	P69I	Neutral	0.32
NOTCH3	Q9UM47-1.2	P69K	Neutral	0.021
NOTCH3	Q9UM47-1.2	P69L	Neutral	0.32
NOTCH3	Q9UM47-1.2	P69M	Neutral	0.093
NOTCH3	Q9UM47-1.2	P69N	Neutral	0.103
NOTCH3	Q9UM47-1.2	P69Q	Neutral	0.023
NOTCH3	Q9UM47-1.2	P69R	Neutral	0.086
NOTCH3	Q9UM47-1.2	P69S	Neutral	0.024
NOTCH3	Q9UM47-1.2	P69T	Neutral	0.025
NOTCH3	Q9UM47-1.2	P69V	Neutral	0.1
NOTCH3	Q9UM47-1.2	P69W	Pathogenic	0.649
NOTCH3	Q9UM47-1.2	P69Y	Neutral	0.304
NOTCH3	Q9UM47-1.2	G70A	Neutral	0.022
NOTCH3	Q9UM47-1.2	G70C	Pathogenic	0.663
NOTCH3	Q9UM47-1.2	G70D	Neutral	0.085
NOTCH3	Q9UM47-1.2	G70E	Neutral	0.283
NOTCH3	Q9UM47-1.2	G70F	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	G70H	Neutral	0.275
NOTCH3	Q9UM47-1.2	G70I	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	G70K	Neutral	0.264
NOTCH3	Q9UM47-1.2	G70L	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	G70M	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	G70N	Neutral	0.02
NOTCH3	Q9UM47-1.2	G70P	Neutral	0.298
NOTCH3	Q9UM47-1.2	G70Q	Neutral	0.278
NOTCH3	Q9UM47-1.2	G70R	Neutral	0.254
NOTCH3	Q9UM47-1.2	G70S	Neutral	0.021
NOTCH3	Q9UM47-1.2	G70T	Neutral	0.295
NOTCH3	Q9UM47-1.2	G70V	Pathogenic	0.647
NOTCH3	Q9UM47-1.2	G70W	Neutral	0.245
NOTCH3	Q9UM47-1.2	G70Y	Pathogenic	0.614
NOTCH3	Q9UM47-1.2	W71A	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	W71C	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	W71D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	W71E	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	W71F	Neutral	0.052
NOTCH3	Q9UM47-1.2	W71G	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	W71H	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	W71I	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	W71K	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	W71L	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	W71M	Pathogenic	0.522
NOTCH3	Q9UM47-1.2	W71N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	W71P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	W71Q	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	W71R	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	W71S	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	W71T	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	W71V	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	W71Y	Neutral	0.012
NOTCH3	Q9UM47-1.2	V72A	Neutral	0.045
NOTCH3	Q9UM47-1.2	V72C	Neutral	0.186
NOTCH3	Q9UM47-1.2	V72D	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	V72E	Pathogenic	0.527
NOTCH3	Q9UM47-1.2	V72F	Neutral	0.18
NOTCH3	Q9UM47-1.2	V72G	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	V72H	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	V72I	Neutral	0.001
NOTCH3	Q9UM47-1.2	V72K	Pathogenic	0.503
NOTCH3	Q9UM47-1.2	V72L	Neutral	0.011
NOTCH3	Q9UM47-1.2	V72M	Neutral	0.011
NOTCH3	Q9UM47-1.2	V72N	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	V72P	Pathogenic	0.514
NOTCH3	Q9UM47-1.2	V72Q	Pathogenic	0.522
NOTCH3	Q9UM47-1.2	V72R	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	V72S	Neutral	0.499
NOTCH3	Q9UM47-1.2	V72T	Neutral	0.049
NOTCH3	Q9UM47-1.2	V72W	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	V72Y	Neutral	0.176
NOTCH3	Q9UM47-1.2	G73A	Neutral	0.193
NOTCH3	Q9UM47-1.2	G73C	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G73D	Neutral	0.499
NOTCH3	Q9UM47-1.2	G73E	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	G73F	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	G73H	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	G73I	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	G73K	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	G73L	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	G73M	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	G73N	Neutral	0.176
NOTCH3	Q9UM47-1.2	G73P	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	G73Q	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	G73R	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	G73S	Neutral	0.189
NOTCH3	Q9UM47-1.2	G73T	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	G73V	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	G73W	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	G73Y	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	E74A	Neutral	0.196
NOTCH3	Q9UM47-1.2	E74C	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	E74D	Neutral	0.003
NOTCH3	Q9UM47-1.2	E74F	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	E74G	Pathogenic	0.506
NOTCH3	Q9UM47-1.2	E74H	Neutral	0.057
NOTCH3	Q9UM47-1.2	E74I	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	E74K	Neutral	0.012
NOTCH3	Q9UM47-1.2	E74L	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	E74M	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	E74N	Neutral	0.056
NOTCH3	Q9UM47-1.2	E74P	Neutral	0.21
NOTCH3	Q9UM47-1.2	E74Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	E74R	Neutral	0.051
NOTCH3	Q9UM47-1.2	E74S	Neutral	0.052
NOTCH3	Q9UM47-1.2	E74T	Neutral	0.212
NOTCH3	Q9UM47-1.2	E74V	Pathogenic	0.564
NOTCH3	Q9UM47-1.2	E74W	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	E74Y	Pathogenic	0.536
NOTCH3	Q9UM47-1.2	R75A	Neutral	0.169
NOTCH3	Q9UM47-1.2	R75C	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	R75D	Pathogenic	0.502
NOTCH3	Q9UM47-1.2	R75E	Neutral	0.05
NOTCH3	Q9UM47-1.2	R75F	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	R75G	Neutral	0.462
NOTCH3	Q9UM47-1.2	R75H	Neutral	0.052
NOTCH3	Q9UM47-1.2	R75I	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	R75K	Neutral	0.003
NOTCH3	Q9UM47-1.2	R75L	Pathogenic	0.539
NOTCH3	Q9UM47-1.2	R75M	Neutral	0.204
NOTCH3	Q9UM47-1.2	R75N	Neutral	0.047
NOTCH3	Q9UM47-1.2	R75P	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	R75Q	Neutral	0.012
NOTCH3	Q9UM47-1.2	R75S	Neutral	0.172
NOTCH3	Q9UM47-1.2	R75T	Neutral	0.184
NOTCH3	Q9UM47-1.2	R75V	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	R75W	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	R75Y	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	C76A	Neutral	0.435
NOTCH3	Q9UM47-1.2	C76D	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C76E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C76F	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	C76G	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C76H	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C76I	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	C76K	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C76L	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	C76M	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	C76N	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C76P	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C76Q	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C76R	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	C76S	Pathogenic	0.782
NOTCH3	Q9UM47-1.2	C76T	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	C76V	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	C76W	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	C76Y	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	Q77A	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	Q77C	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	Q77D	Neutral	0.34
NOTCH3	Q9UM47-1.2	Q77E	Neutral	0.026
NOTCH3	Q9UM47-1.2	Q77F	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	Q77G	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	Q77H	Neutral	0.356
NOTCH3	Q9UM47-1.2	Q77I	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	Q77K	Neutral	0.103
NOTCH3	Q9UM47-1.2	Q77L	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	Q77M	Neutral	0.353
NOTCH3	Q9UM47-1.2	Q77N	Neutral	0.344
NOTCH3	Q9UM47-1.2	Q77P	Pathogenic	0.701
NOTCH3	Q9UM47-1.2	Q77R	Neutral	0.098
NOTCH3	Q9UM47-1.2	Q77S	Neutral	0.324
NOTCH3	Q9UM47-1.2	Q77T	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	Q77V	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	Q77W	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	Q77Y	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	L78A	Neutral	0.015
NOTCH3	Q9UM47-1.2	L78C	Neutral	0.016
NOTCH3	Q9UM47-1.2	L78D	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	L78E	Neutral	0.27
NOTCH3	Q9UM47-1.2	L78F	Neutral	0.004
NOTCH3	Q9UM47-1.2	L78G	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	L78H	Neutral	0.276
NOTCH3	Q9UM47-1.2	L78I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L78K	Neutral	0.076
NOTCH3	Q9UM47-1.2	L78M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L78N	Neutral	0.26
NOTCH3	Q9UM47-1.2	L78P	Neutral	0.254
NOTCH3	Q9UM47-1.2	L78Q	Neutral	0.076
NOTCH3	Q9UM47-1.2	L78R	Neutral	0.073
NOTCH3	Q9UM47-1.2	L78S	Neutral	0.066
NOTCH3	Q9UM47-1.2	L78T	Neutral	0.016
NOTCH3	Q9UM47-1.2	L78V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L78W	Neutral	0.068
NOTCH3	Q9UM47-1.2	L78Y	Neutral	0.017
NOTCH3	Q9UM47-1.2	E79A	Neutral	0.014
NOTCH3	Q9UM47-1.2	E79C	Pathogenic	0.584
NOTCH3	Q9UM47-1.2	E79D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E79F	Neutral	0.235
NOTCH3	Q9UM47-1.2	E79G	Neutral	0.055
NOTCH3	Q9UM47-1.2	E79H	Neutral	0.003
NOTCH3	Q9UM47-1.2	E79I	Neutral	0.242
NOTCH3	Q9UM47-1.2	E79K	Neutral	0.001
NOTCH3	Q9UM47-1.2	E79L	Neutral	0.242
NOTCH3	Q9UM47-1.2	E79M	Neutral	0.065
NOTCH3	Q9UM47-1.2	E79N	Neutral	0.003
NOTCH3	Q9UM47-1.2	E79P	Neutral	0.015
NOTCH3	Q9UM47-1.2	E79Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E79R	Neutral	0.003
NOTCH3	Q9UM47-1.2	E79S	Neutral	0.003
NOTCH3	Q9UM47-1.2	E79T	Neutral	0.015
NOTCH3	Q9UM47-1.2	E79V	Neutral	0.068
NOTCH3	Q9UM47-1.2	E79W	Neutral	0.216
NOTCH3	Q9UM47-1.2	E79Y	Neutral	0.061
NOTCH3	Q9UM47-1.2	D80A	Pathogenic	0.549
NOTCH3	Q9UM47-1.2	D80C	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	D80E	Neutral	0.003
NOTCH3	Q9UM47-1.2	D80F	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	D80G	Neutral	0.199
NOTCH3	Q9UM47-1.2	D80H	Neutral	0.209
NOTCH3	Q9UM47-1.2	D80I	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	D80K	Neutral	0.197
NOTCH3	Q9UM47-1.2	D80L	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	D80M	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	D80N	Neutral	0.014
NOTCH3	Q9UM47-1.2	D80P	Neutral	0.227
NOTCH3	Q9UM47-1.2	D80Q	Neutral	0.055
NOTCH3	Q9UM47-1.2	D80R	Pathogenic	0.515
NOTCH3	Q9UM47-1.2	D80S	Neutral	0.057
NOTCH3	Q9UM47-1.2	D80T	Neutral	0.225
NOTCH3	Q9UM47-1.2	D80V	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	D80W	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	D80Y	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	P81A	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	P81C	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	P81D	Pathogenic	0.61
NOTCH3	Q9UM47-1.2	P81E	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	P81F	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	P81G	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	P81H	Pathogenic	0.864
NOTCH3	Q9UM47-1.2	P81I	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	P81K	Pathogenic	0.569
NOTCH3	Q9UM47-1.2	P81L	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	P81M	Pathogenic	0.861
NOTCH3	Q9UM47-1.2	P81N	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	P81Q	Pathogenic	0.588
NOTCH3	Q9UM47-1.2	P81R	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	P81S	Pathogenic	0.594
NOTCH3	Q9UM47-1.2	P81T	Pathogenic	0.606
NOTCH3	Q9UM47-1.2	P81V	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	P81W	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	P81Y	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	C82A	Neutral	0.431
NOTCH3	Q9UM47-1.2	C82D	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C82E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C82F	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	C82G	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C82H	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C82I	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	C82K	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C82L	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	C82M	Pathogenic	0.761
NOTCH3	Q9UM47-1.2	C82N	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C82P	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C82Q	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C82R	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	C82S	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	C82T	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	C82V	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	C82W	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	C82Y	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	H83A	Neutral	0.299
NOTCH3	Q9UM47-1.2	H83C	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	H83D	Neutral	0.094
NOTCH3	Q9UM47-1.2	H83E	Neutral	0.024
NOTCH3	Q9UM47-1.2	H83F	Neutral	0.098
NOTCH3	Q9UM47-1.2	H83G	Neutral	0.284
NOTCH3	Q9UM47-1.2	H83I	Pathogenic	0.701
NOTCH3	Q9UM47-1.2	H83K	Neutral	0.097
NOTCH3	Q9UM47-1.2	H83L	Pathogenic	0.701
NOTCH3	Q9UM47-1.2	H83M	Neutral	0.339
NOTCH3	Q9UM47-1.2	H83N	Neutral	0.005
NOTCH3	Q9UM47-1.2	H83P	Neutral	0.319
NOTCH3	Q9UM47-1.2	H83Q	Neutral	0.024
NOTCH3	Q9UM47-1.2	H83R	Neutral	0.022
NOTCH3	Q9UM47-1.2	H83S	Neutral	0.088
NOTCH3	Q9UM47-1.2	H83T	Neutral	0.321
NOTCH3	Q9UM47-1.2	H83V	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	H83W	Neutral	0.308
NOTCH3	Q9UM47-1.2	H83Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	S84A	Neutral	0.004
NOTCH3	Q9UM47-1.2	S84C	Neutral	0.076
NOTCH3	Q9UM47-1.2	S84D	Neutral	0.017
NOTCH3	Q9UM47-1.2	S84E	Neutral	0.016
NOTCH3	Q9UM47-1.2	S84F	Neutral	0.237
NOTCH3	Q9UM47-1.2	S84G	Neutral	0.017
NOTCH3	Q9UM47-1.2	S84H	Neutral	0.067
NOTCH3	Q9UM47-1.2	S84I	Neutral	0.245
NOTCH3	Q9UM47-1.2	S84K	Neutral	0.015
NOTCH3	Q9UM47-1.2	S84L	Neutral	0.245
NOTCH3	Q9UM47-1.2	S84M	Neutral	0.066
NOTCH3	Q9UM47-1.2	S84N	Neutral	0.004
NOTCH3	Q9UM47-1.2	S84P	Neutral	0.075
NOTCH3	Q9UM47-1.2	S84Q	Neutral	0.016
NOTCH3	Q9UM47-1.2	S84R	Neutral	0.061
NOTCH3	Q9UM47-1.2	S84T	Neutral	0.004
NOTCH3	Q9UM47-1.2	S84V	Neutral	0.258
NOTCH3	Q9UM47-1.2	S84W	Pathogenic	0.561
NOTCH3	Q9UM47-1.2	S84Y	Neutral	0.232
NOTCH3	Q9UM47-1.2	G85A	Neutral	0.003
NOTCH3	Q9UM47-1.2	G85C	Neutral	0.208
NOTCH3	Q9UM47-1.2	G85D	Neutral	0.012
NOTCH3	Q9UM47-1.2	G85E	Neutral	0.05
NOTCH3	Q9UM47-1.2	G85F	Neutral	0.179
NOTCH3	Q9UM47-1.2	G85H	Neutral	0.048
NOTCH3	Q9UM47-1.2	G85I	Pathogenic	0.509
NOTCH3	Q9UM47-1.2	G85K	Neutral	0.046
NOTCH3	Q9UM47-1.2	G85L	Pathogenic	0.509
NOTCH3	Q9UM47-1.2	G85M	Neutral	0.185
NOTCH3	Q9UM47-1.2	G85N	Neutral	0.003
NOTCH3	Q9UM47-1.2	G85P	Neutral	0.054
NOTCH3	Q9UM47-1.2	G85Q	Neutral	0.049
NOTCH3	Q9UM47-1.2	G85R	Neutral	0.043
NOTCH3	Q9UM47-1.2	G85S	Neutral	0.003
NOTCH3	Q9UM47-1.2	G85T	Neutral	0.053
NOTCH3	Q9UM47-1.2	G85V	Neutral	0.196
NOTCH3	Q9UM47-1.2	G85W	Neutral	0.041
NOTCH3	Q9UM47-1.2	G85Y	Neutral	0.175
NOTCH3	Q9UM47-1.2	P86A	Neutral	0.179
NOTCH3	Q9UM47-1.2	P86C	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	P86D	Neutral	0.194
NOTCH3	Q9UM47-1.2	P86E	Neutral	0.183
NOTCH3	Q9UM47-1.2	P86F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	P86G	Neutral	0.481
NOTCH3	Q9UM47-1.2	P86H	Neutral	0.494
NOTCH3	Q9UM47-1.2	P86I	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	P86K	Neutral	0.169
NOTCH3	Q9UM47-1.2	P86L	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	P86M	Neutral	0.488
NOTCH3	Q9UM47-1.2	P86N	Pathogenic	0.517
NOTCH3	Q9UM47-1.2	P86Q	Neutral	0.179
NOTCH3	Q9UM47-1.2	P86R	Neutral	0.468
NOTCH3	Q9UM47-1.2	P86S	Neutral	0.183
NOTCH3	Q9UM47-1.2	P86T	Neutral	0.191
NOTCH3	Q9UM47-1.2	P86V	Pathogenic	0.507
NOTCH3	Q9UM47-1.2	P86W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	P86Y	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C87A	Neutral	0.435
NOTCH3	Q9UM47-1.2	C87D	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C87E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C87F	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	C87G	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C87H	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C87I	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	C87K	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C87L	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	C87M	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	C87N	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C87P	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C87Q	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C87R	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	C87S	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	C87T	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	C87V	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	C87W	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	C87Y	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	A88C	Neutral	0.004
NOTCH3	Q9UM47-1.2	A88D	Neutral	0.078
NOTCH3	Q9UM47-1.2	A88E	Neutral	0.017
NOTCH3	Q9UM47-1.2	A88F	Neutral	0.067
NOTCH3	Q9UM47-1.2	A88G	Neutral	0.004
NOTCH3	Q9UM47-1.2	A88H	Neutral	0.071
NOTCH3	Q9UM47-1.2	A88I	Neutral	0.016
NOTCH3	Q9UM47-1.2	A88K	Neutral	0.016
NOTCH3	Q9UM47-1.2	A88L	Neutral	0.016
NOTCH3	Q9UM47-1.2	A88M	Neutral	0.016
NOTCH3	Q9UM47-1.2	A88N	Neutral	0.077
NOTCH3	Q9UM47-1.2	A88P	Neutral	0.018
NOTCH3	Q9UM47-1.2	A88Q	Neutral	0.017
NOTCH3	Q9UM47-1.2	A88R	Neutral	0.015
NOTCH3	Q9UM47-1.2	A88S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A88T	Neutral	0.004
NOTCH3	Q9UM47-1.2	A88V	Neutral	0.004
NOTCH3	Q9UM47-1.2	A88W	Neutral	0.228
NOTCH3	Q9UM47-1.2	A88Y	Neutral	0.065
NOTCH3	Q9UM47-1.2	G89A	Neutral	0.005
NOTCH3	Q9UM47-1.2	G89C	Neutral	0.317
NOTCH3	Q9UM47-1.2	G89D	Neutral	0.021
NOTCH3	Q9UM47-1.2	G89E	Neutral	0.085
NOTCH3	Q9UM47-1.2	G89F	Neutral	0.279
NOTCH3	Q9UM47-1.2	G89H	Neutral	0.082
NOTCH3	Q9UM47-1.2	G89I	Pathogenic	0.647
NOTCH3	Q9UM47-1.2	G89K	Neutral	0.078
NOTCH3	Q9UM47-1.2	G89L	Pathogenic	0.647
NOTCH3	Q9UM47-1.2	G89M	Neutral	0.286
NOTCH3	Q9UM47-1.2	G89N	Neutral	0.005
NOTCH3	Q9UM47-1.2	G89P	Neutral	0.091
NOTCH3	Q9UM47-1.2	G89Q	Neutral	0.083
NOTCH3	Q9UM47-1.2	G89R	Neutral	0.074
NOTCH3	Q9UM47-1.2	G89S	Neutral	0.005
NOTCH3	Q9UM47-1.2	G89T	Neutral	0.09
NOTCH3	Q9UM47-1.2	G89V	Neutral	0.302
NOTCH3	Q9UM47-1.2	G89W	Neutral	0.071
NOTCH3	Q9UM47-1.2	G89Y	Neutral	0.273
NOTCH3	Q9UM47-1.2	R90A	Neutral	0.045
NOTCH3	Q9UM47-1.2	R90C	Pathogenic	0.513
NOTCH3	Q9UM47-1.2	R90D	Neutral	0.189
NOTCH3	Q9UM47-1.2	R90E	Neutral	0.012
NOTCH3	Q9UM47-1.2	R90F	Pathogenic	0.562
NOTCH3	Q9UM47-1.2	R90G	Neutral	0.166
NOTCH3	Q9UM47-1.2	R90H	Neutral	0.012
NOTCH3	Q9UM47-1.2	R90I	Pathogenic	0.551
NOTCH3	Q9UM47-1.2	R90K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R90L	Neutral	0.212
NOTCH3	Q9UM47-1.2	R90M	Neutral	0.056
NOTCH3	Q9UM47-1.2	R90N	Neutral	0.011
NOTCH3	Q9UM47-1.2	R90P	Neutral	0.19
NOTCH3	Q9UM47-1.2	R90Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R90S	Neutral	0.046
NOTCH3	Q9UM47-1.2	R90T	Neutral	0.049
NOTCH3	Q9UM47-1.2	R90V	Pathogenic	0.532
NOTCH3	Q9UM47-1.2	R90W	Pathogenic	0.561
NOTCH3	Q9UM47-1.2	R90Y	Neutral	0.223
NOTCH3	Q9UM47-1.2	G91A	Neutral	0.149
NOTCH3	Q9UM47-1.2	G91C	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	G91D	Neutral	0.423
NOTCH3	Q9UM47-1.2	G91E	Pathogenic	0.756
NOTCH3	Q9UM47-1.2	G91F	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	G91H	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	G91I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	G91K	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	G91L	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	G91M	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	G91N	Neutral	0.136
NOTCH3	Q9UM47-1.2	G91P	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	G91Q	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	G91R	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	G91S	Neutral	0.146
NOTCH3	Q9UM47-1.2	G91T	Pathogenic	0.767
NOTCH3	Q9UM47-1.2	G91V	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	G91W	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	G91Y	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	V92A	Neutral	0.009
NOTCH3	Q9UM47-1.2	V92C	Neutral	0.041
NOTCH3	Q9UM47-1.2	V92D	Neutral	0.476
NOTCH3	Q9UM47-1.2	V92E	Neutral	0.172
NOTCH3	Q9UM47-1.2	V92F	Neutral	0.039
NOTCH3	Q9UM47-1.2	V92G	Neutral	0.434
NOTCH3	Q9UM47-1.2	V92H	Neutral	0.476
NOTCH3	Q9UM47-1.2	V92I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V92K	Neutral	0.158
NOTCH3	Q9UM47-1.2	V92L	Neutral	0.002
NOTCH3	Q9UM47-1.2	V92M	Neutral	0.002
NOTCH3	Q9UM47-1.2	V92N	Neutral	0.481
NOTCH3	Q9UM47-1.2	V92P	Neutral	0.164
NOTCH3	Q9UM47-1.2	V92Q	Neutral	0.169
NOTCH3	Q9UM47-1.2	V92R	Neutral	0.449
NOTCH3	Q9UM47-1.2	V92S	Neutral	0.156
NOTCH3	Q9UM47-1.2	V92T	Neutral	0.01
NOTCH3	Q9UM47-1.2	V92W	Neutral	0.432
NOTCH3	Q9UM47-1.2	V92Y	Neutral	0.038
NOTCH3	Q9UM47-1.2	C93A	Neutral	0.427
NOTCH3	Q9UM47-1.2	C93D	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C93E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C93F	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	C93G	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C93H	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C93I	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	C93K	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	C93L	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	C93M	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	C93N	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C93P	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C93Q	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C93R	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	C93S	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	C93T	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	C93V	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	C93W	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	C93Y	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	Q94A	Neutral	0.017
NOTCH3	Q9UM47-1.2	Q94C	Neutral	0.274
NOTCH3	Q9UM47-1.2	Q94D	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q94E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q94F	Neutral	0.281
NOTCH3	Q9UM47-1.2	Q94G	Neutral	0.066
NOTCH3	Q9UM47-1.2	Q94H	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q94I	Neutral	0.29
NOTCH3	Q9UM47-1.2	Q94K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q94L	Neutral	0.082
NOTCH3	Q9UM47-1.2	Q94M	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q94N	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q94P	Neutral	0.018
NOTCH3	Q9UM47-1.2	Q94R	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q94S	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q94T	Neutral	0.018
NOTCH3	Q9UM47-1.2	Q94V	Neutral	0.082
NOTCH3	Q9UM47-1.2	Q94W	Neutral	0.072
NOTCH3	Q9UM47-1.2	Q94Y	Neutral	0.018
NOTCH3	Q9UM47-1.2	S95A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S95C	Neutral	0.026
NOTCH3	Q9UM47-1.2	S95D	Neutral	0.006
NOTCH3	Q9UM47-1.2	S95E	Neutral	0.005
NOTCH3	Q9UM47-1.2	S95F	Neutral	0.091
NOTCH3	Q9UM47-1.2	S95G	Neutral	0.005
NOTCH3	Q9UM47-1.2	S95H	Neutral	0.023
NOTCH3	Q9UM47-1.2	S95I	Neutral	0.094
NOTCH3	Q9UM47-1.2	S95K	Neutral	0.005
NOTCH3	Q9UM47-1.2	S95L	Neutral	0.094
NOTCH3	Q9UM47-1.2	S95M	Neutral	0.022
NOTCH3	Q9UM47-1.2	S95N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S95P	Neutral	0.025
NOTCH3	Q9UM47-1.2	S95Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	S95R	Neutral	0.02
NOTCH3	Q9UM47-1.2	S95T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S95V	Neutral	0.1
NOTCH3	Q9UM47-1.2	S95W	Neutral	0.291
NOTCH3	Q9UM47-1.2	S95Y	Neutral	0.088
NOTCH3	Q9UM47-1.2	S96A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S96C	Neutral	0.015
NOTCH3	Q9UM47-1.2	S96D	Neutral	0.003
NOTCH3	Q9UM47-1.2	S96E	Neutral	0.003
NOTCH3	Q9UM47-1.2	S96F	Neutral	0.056
NOTCH3	Q9UM47-1.2	S96G	Neutral	0.003
NOTCH3	Q9UM47-1.2	S96H	Neutral	0.013
NOTCH3	Q9UM47-1.2	S96I	Neutral	0.058
NOTCH3	Q9UM47-1.2	S96K	Neutral	0.003
NOTCH3	Q9UM47-1.2	S96L	Neutral	0.058
NOTCH3	Q9UM47-1.2	S96M	Neutral	0.013
NOTCH3	Q9UM47-1.2	S96N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S96P	Neutral	0.015
NOTCH3	Q9UM47-1.2	S96Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	S96R	Neutral	0.012
NOTCH3	Q9UM47-1.2	S96T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S96V	Neutral	0.062
NOTCH3	Q9UM47-1.2	S96W	Neutral	0.194
NOTCH3	Q9UM47-1.2	S96Y	Neutral	0.054
NOTCH3	Q9UM47-1.2	V97A	Neutral	0.007
NOTCH3	Q9UM47-1.2	V97C	Neutral	0.032
NOTCH3	Q9UM47-1.2	V97D	Neutral	0.415
NOTCH3	Q9UM47-1.2	V97E	Neutral	0.139
NOTCH3	Q9UM47-1.2	V97F	Neutral	0.031
NOTCH3	Q9UM47-1.2	V97G	Neutral	0.373
NOTCH3	Q9UM47-1.2	V97H	Neutral	0.414
NOTCH3	Q9UM47-1.2	V97I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V97K	Neutral	0.128
NOTCH3	Q9UM47-1.2	V97L	Neutral	0.002
NOTCH3	Q9UM47-1.2	V97M	Neutral	0.002
NOTCH3	Q9UM47-1.2	V97N	Neutral	0.419
NOTCH3	Q9UM47-1.2	V97P	Neutral	0.133
NOTCH3	Q9UM47-1.2	V97Q	Neutral	0.136
NOTCH3	Q9UM47-1.2	V97R	Neutral	0.388
NOTCH3	Q9UM47-1.2	V97S	Neutral	0.126
NOTCH3	Q9UM47-1.2	V97T	Neutral	0.007
NOTCH3	Q9UM47-1.2	V97W	Neutral	0.372
NOTCH3	Q9UM47-1.2	V97Y	Neutral	0.03
NOTCH3	Q9UM47-1.2	V98A	Neutral	0.007
NOTCH3	Q9UM47-1.2	V98C	Neutral	0.032
NOTCH3	Q9UM47-1.2	V98D	Neutral	0.417
NOTCH3	Q9UM47-1.2	V98E	Neutral	0.14
NOTCH3	Q9UM47-1.2	V98F	Neutral	0.031
NOTCH3	Q9UM47-1.2	V98G	Neutral	0.376
NOTCH3	Q9UM47-1.2	V98H	Neutral	0.417
NOTCH3	Q9UM47-1.2	V98I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V98K	Neutral	0.129
NOTCH3	Q9UM47-1.2	V98L	Neutral	0.002
NOTCH3	Q9UM47-1.2	V98M	Neutral	0.002
NOTCH3	Q9UM47-1.2	V98N	Neutral	0.422
NOTCH3	Q9UM47-1.2	V98P	Neutral	0.134
NOTCH3	Q9UM47-1.2	V98Q	Neutral	0.138
NOTCH3	Q9UM47-1.2	V98R	Neutral	0.391
NOTCH3	Q9UM47-1.2	V98S	Neutral	0.127
NOTCH3	Q9UM47-1.2	V98T	Neutral	0.008
NOTCH3	Q9UM47-1.2	V98W	Neutral	0.375
NOTCH3	Q9UM47-1.2	V98Y	Neutral	0.03
NOTCH3	Q9UM47-1.2	A99C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A99D	Neutral	0.05
NOTCH3	Q9UM47-1.2	A99E	Neutral	0.011
NOTCH3	Q9UM47-1.2	A99F	Neutral	0.043
NOTCH3	Q9UM47-1.2	A99G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A99H	Neutral	0.045
NOTCH3	Q9UM47-1.2	A99I	Neutral	0.01
NOTCH3	Q9UM47-1.2	A99K	Neutral	0.01
NOTCH3	Q9UM47-1.2	A99L	Neutral	0.01
NOTCH3	Q9UM47-1.2	A99M	Neutral	0.01
NOTCH3	Q9UM47-1.2	A99N	Neutral	0.049
NOTCH3	Q9UM47-1.2	A99P	Neutral	0.011
NOTCH3	Q9UM47-1.2	A99Q	Neutral	0.01
NOTCH3	Q9UM47-1.2	A99R	Neutral	0.009
NOTCH3	Q9UM47-1.2	A99S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A99T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A99V	Neutral	0.002
NOTCH3	Q9UM47-1.2	A99W	Neutral	0.155
NOTCH3	Q9UM47-1.2	A99Y	Neutral	0.042
NOTCH3	Q9UM47-1.2	G100A	Neutral	0.032
NOTCH3	Q9UM47-1.2	G100C	Pathogenic	0.743
NOTCH3	Q9UM47-1.2	G100D	Neutral	0.12
NOTCH3	Q9UM47-1.2	G100E	Neutral	0.367
NOTCH3	Q9UM47-1.2	G100F	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	G100H	Neutral	0.358
NOTCH3	Q9UM47-1.2	G100I	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	G100K	Neutral	0.344
NOTCH3	Q9UM47-1.2	G100L	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	G100M	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	G100N	Neutral	0.029
NOTCH3	Q9UM47-1.2	G100P	Neutral	0.384
NOTCH3	Q9UM47-1.2	G100Q	Neutral	0.361
NOTCH3	Q9UM47-1.2	G100R	Neutral	0.333
NOTCH3	Q9UM47-1.2	G100S	Neutral	0.031
NOTCH3	Q9UM47-1.2	G100T	Neutral	0.38
NOTCH3	Q9UM47-1.2	G100V	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	G100W	Neutral	0.323
NOTCH3	Q9UM47-1.2	G100Y	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	T101A	Neutral	0.011
NOTCH3	Q9UM47-1.2	T101C	Neutral	0.051
NOTCH3	Q9UM47-1.2	T101D	Neutral	0.052
NOTCH3	Q9UM47-1.2	T101E	Neutral	0.049
NOTCH3	Q9UM47-1.2	T101F	Neutral	0.176
NOTCH3	Q9UM47-1.2	T101G	Neutral	0.173
NOTCH3	Q9UM47-1.2	T101H	Neutral	0.184
NOTCH3	Q9UM47-1.2	T101I	Neutral	0.047
NOTCH3	Q9UM47-1.2	T101K	Neutral	0.045
NOTCH3	Q9UM47-1.2	T101L	Neutral	0.047
NOTCH3	Q9UM47-1.2	T101M	Neutral	0.047
NOTCH3	Q9UM47-1.2	T101N	Neutral	0.012
NOTCH3	Q9UM47-1.2	T101P	Neutral	0.051
NOTCH3	Q9UM47-1.2	T101Q	Neutral	0.048
NOTCH3	Q9UM47-1.2	T101R	Neutral	0.043
NOTCH3	Q9UM47-1.2	T101S	Neutral	0.002
NOTCH3	Q9UM47-1.2	T101V	Neutral	0.011
NOTCH3	Q9UM47-1.2	T101W	Neutral	0.162
NOTCH3	Q9UM47-1.2	T101Y	Neutral	0.172
NOTCH3	Q9UM47-1.2	A102C	Neutral	0.027
NOTCH3	Q9UM47-1.2	A102D	Neutral	0.366
NOTCH3	Q9UM47-1.2	A102E	Neutral	0.105
NOTCH3	Q9UM47-1.2	A102F	Neutral	0.328
NOTCH3	Q9UM47-1.2	A102G	Neutral	0.027
NOTCH3	Q9UM47-1.2	A102H	Neutral	0.34
NOTCH3	Q9UM47-1.2	A102I	Neutral	0.101
NOTCH3	Q9UM47-1.2	A102K	Neutral	0.097
NOTCH3	Q9UM47-1.2	A102L	Neutral	0.1
NOTCH3	Q9UM47-1.2	A102M	Neutral	0.1
NOTCH3	Q9UM47-1.2	A102N	Neutral	0.361
NOTCH3	Q9UM47-1.2	A102P	Neutral	0.112
NOTCH3	Q9UM47-1.2	A102Q	Neutral	0.103
NOTCH3	Q9UM47-1.2	A102R	Neutral	0.092
NOTCH3	Q9UM47-1.2	A102S	Neutral	0.006
NOTCH3	Q9UM47-1.2	A102T	Neutral	0.027
NOTCH3	Q9UM47-1.2	A102V	Neutral	0.026
NOTCH3	Q9UM47-1.2	A102W	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	A102Y	Neutral	0.321
NOTCH3	Q9UM47-1.2	R103A	Neutral	0.018
NOTCH3	Q9UM47-1.2	R103C	Neutral	0.293
NOTCH3	Q9UM47-1.2	R103D	Neutral	0.084
NOTCH3	Q9UM47-1.2	R103E	Neutral	0.005
NOTCH3	Q9UM47-1.2	R103F	Neutral	0.335
NOTCH3	Q9UM47-1.2	R103G	Neutral	0.072
NOTCH3	Q9UM47-1.2	R103H	Neutral	0.005
NOTCH3	Q9UM47-1.2	R103I	Neutral	0.325
NOTCH3	Q9UM47-1.2	R103K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R103L	Neutral	0.096
NOTCH3	Q9UM47-1.2	R103M	Neutral	0.023
NOTCH3	Q9UM47-1.2	R103N	Neutral	0.004
NOTCH3	Q9UM47-1.2	R103P	Neutral	0.084
NOTCH3	Q9UM47-1.2	R103Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	R103S	Neutral	0.018
NOTCH3	Q9UM47-1.2	R103T	Neutral	0.02
NOTCH3	Q9UM47-1.2	R103V	Neutral	0.309
NOTCH3	Q9UM47-1.2	R103W	Neutral	0.334
NOTCH3	Q9UM47-1.2	R103Y	Neutral	0.101
NOTCH3	Q9UM47-1.2	F104A	Pathogenic	0.615
NOTCH3	Q9UM47-1.2	F104C	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	F104D	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	F104E	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	F104G	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	F104H	Neutral	0.299
NOTCH3	Q9UM47-1.2	F104I	Neutral	0.087
NOTCH3	Q9UM47-1.2	F104K	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	F104L	Neutral	0.087
NOTCH3	Q9UM47-1.2	F104M	Neutral	0.087
NOTCH3	Q9UM47-1.2	F104N	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	F104P	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	F104Q	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	F104R	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	F104S	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	F104T	Pathogenic	0.638
NOTCH3	Q9UM47-1.2	F104V	Neutral	0.287
NOTCH3	Q9UM47-1.2	F104W	Neutral	0.019
NOTCH3	Q9UM47-1.2	F104Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	S105A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S105C	Neutral	0.01
NOTCH3	Q9UM47-1.2	S105D	Neutral	0.002
NOTCH3	Q9UM47-1.2	S105E	Neutral	0.002
NOTCH3	Q9UM47-1.2	S105F	Neutral	0.038
NOTCH3	Q9UM47-1.2	S105G	Neutral	0.002
NOTCH3	Q9UM47-1.2	S105H	Neutral	0.009
NOTCH3	Q9UM47-1.2	S105I	Neutral	0.04
NOTCH3	Q9UM47-1.2	S105K	Neutral	0.002
NOTCH3	Q9UM47-1.2	S105L	Neutral	0.04
NOTCH3	Q9UM47-1.2	S105M	Neutral	0.009
NOTCH3	Q9UM47-1.2	S105N	Neutral	0.0
NOTCH3	Q9UM47-1.2	S105P	Neutral	0.01
NOTCH3	Q9UM47-1.2	S105Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	S105R	Neutral	0.008
NOTCH3	Q9UM47-1.2	S105T	Neutral	0.0
NOTCH3	Q9UM47-1.2	S105V	Neutral	0.042
NOTCH3	Q9UM47-1.2	S105W	Neutral	0.14
NOTCH3	Q9UM47-1.2	S105Y	Neutral	0.037
NOTCH3	Q9UM47-1.2	C106A	Neutral	0.441
NOTCH3	Q9UM47-1.2	C106D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C106E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C106F	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	C106G	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C106H	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C106I	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	C106K	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C106L	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	C106M	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	C106N	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C106P	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C106Q	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C106R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C106S	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	C106T	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C106V	Pathogenic	0.782
NOTCH3	Q9UM47-1.2	C106W	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	C106Y	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	R107A	Neutral	0.118
NOTCH3	Q9UM47-1.2	R107C	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	R107D	Neutral	0.399
NOTCH3	Q9UM47-1.2	R107E	Neutral	0.033
NOTCH3	Q9UM47-1.2	R107F	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	R107G	Neutral	0.362
NOTCH3	Q9UM47-1.2	R107H	Neutral	0.035
NOTCH3	Q9UM47-1.2	R107I	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	R107K	Neutral	0.002
NOTCH3	Q9UM47-1.2	R107L	Neutral	0.435
NOTCH3	Q9UM47-1.2	R107M	Neutral	0.144
NOTCH3	Q9UM47-1.2	R107N	Neutral	0.032
NOTCH3	Q9UM47-1.2	R107P	Neutral	0.401
NOTCH3	Q9UM47-1.2	R107Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	R107S	Neutral	0.121
NOTCH3	Q9UM47-1.2	R107T	Neutral	0.129
NOTCH3	Q9UM47-1.2	R107V	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	R107W	Pathogenic	0.785
NOTCH3	Q9UM47-1.2	R107Y	Neutral	0.45
NOTCH3	Q9UM47-1.2	C108A	Neutral	0.425
NOTCH3	Q9UM47-1.2	C108D	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C108E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C108F	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	C108G	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C108H	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C108I	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	C108K	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	C108L	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	C108M	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	C108N	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C108P	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C108Q	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C108R	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	C108S	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	C108T	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	C108V	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	C108W	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	C108Y	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	P109A	Neutral	0.15
NOTCH3	Q9UM47-1.2	P109C	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	P109D	Neutral	0.163
NOTCH3	Q9UM47-1.2	P109E	Neutral	0.153
NOTCH3	Q9UM47-1.2	P109F	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	P109G	Neutral	0.429
NOTCH3	Q9UM47-1.2	P109H	Neutral	0.442
NOTCH3	Q9UM47-1.2	P109I	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	P109K	Neutral	0.141
NOTCH3	Q9UM47-1.2	P109L	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	P109M	Neutral	0.436
NOTCH3	Q9UM47-1.2	P109N	Neutral	0.464
NOTCH3	Q9UM47-1.2	P109Q	Neutral	0.151
NOTCH3	Q9UM47-1.2	P109R	Neutral	0.416
NOTCH3	Q9UM47-1.2	P109S	Neutral	0.154
NOTCH3	Q9UM47-1.2	P109T	Neutral	0.161
NOTCH3	Q9UM47-1.2	P109V	Neutral	0.454
NOTCH3	Q9UM47-1.2	P109W	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	P109Y	Pathogenic	0.767
NOTCH3	Q9UM47-1.2	R110A	Neutral	0.065
NOTCH3	Q9UM47-1.2	R110C	Pathogenic	0.61
NOTCH3	Q9UM47-1.2	R110D	Neutral	0.257
NOTCH3	Q9UM47-1.2	R110E	Neutral	0.018
NOTCH3	Q9UM47-1.2	R110F	Pathogenic	0.656
NOTCH3	Q9UM47-1.2	R110G	Neutral	0.228
NOTCH3	Q9UM47-1.2	R110H	Neutral	0.018
NOTCH3	Q9UM47-1.2	R110I	Pathogenic	0.646
NOTCH3	Q9UM47-1.2	R110K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R110L	Neutral	0.286
NOTCH3	Q9UM47-1.2	R110M	Neutral	0.081
NOTCH3	Q9UM47-1.2	R110N	Neutral	0.017
NOTCH3	Q9UM47-1.2	R110P	Neutral	0.258
NOTCH3	Q9UM47-1.2	R110Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	R110S	Neutral	0.067
NOTCH3	Q9UM47-1.2	R110T	Neutral	0.072
NOTCH3	Q9UM47-1.2	R110V	Pathogenic	0.628
NOTCH3	Q9UM47-1.2	R110W	Pathogenic	0.655
NOTCH3	Q9UM47-1.2	R110Y	Neutral	0.298
NOTCH3	Q9UM47-1.2	G111A	Neutral	0.177
NOTCH3	Q9UM47-1.2	G111C	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	G111D	Neutral	0.473
NOTCH3	Q9UM47-1.2	G111E	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	G111F	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	G111H	Pathogenic	0.785
NOTCH3	Q9UM47-1.2	G111I	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	G111K	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	G111L	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	G111M	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	G111N	Neutral	0.162
NOTCH3	Q9UM47-1.2	G111P	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	G111Q	Pathogenic	0.788
NOTCH3	Q9UM47-1.2	G111R	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	G111S	Neutral	0.173
NOTCH3	Q9UM47-1.2	G111T	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	G111V	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	G111W	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	G111Y	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	F112A	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	F112C	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	F112D	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	F112E	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	F112G	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	F112H	Pathogenic	0.53
NOTCH3	Q9UM47-1.2	F112I	Neutral	0.2
NOTCH3	Q9UM47-1.2	F112K	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	F112L	Neutral	0.2
NOTCH3	Q9UM47-1.2	F112M	Neutral	0.201
NOTCH3	Q9UM47-1.2	F112N	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	F112P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	F112Q	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	F112R	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	F112S	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	F112T	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	F112V	Pathogenic	0.515
NOTCH3	Q9UM47-1.2	F112W	Neutral	0.049
NOTCH3	Q9UM47-1.2	F112Y	Neutral	0.003
NOTCH3	Q9UM47-1.2	R113A	Neutral	0.079
NOTCH3	Q9UM47-1.2	R113C	Pathogenic	0.657
NOTCH3	Q9UM47-1.2	R113D	Neutral	0.297
NOTCH3	Q9UM47-1.2	R113E	Neutral	0.021
NOTCH3	Q9UM47-1.2	R113F	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	R113G	Neutral	0.265
NOTCH3	Q9UM47-1.2	R113H	Neutral	0.022
NOTCH3	Q9UM47-1.2	R113I	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	R113K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R113L	Neutral	0.329
NOTCH3	Q9UM47-1.2	R113M	Neutral	0.097
NOTCH3	Q9UM47-1.2	R113N	Neutral	0.02
NOTCH3	Q9UM47-1.2	R113P	Neutral	0.299
NOTCH3	Q9UM47-1.2	R113Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	R113S	Neutral	0.08
NOTCH3	Q9UM47-1.2	R113T	Neutral	0.086
NOTCH3	Q9UM47-1.2	R113V	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	R113W	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	R113Y	Neutral	0.342
NOTCH3	Q9UM47-1.2	G114A	Neutral	0.192
NOTCH3	Q9UM47-1.2	G114C	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G114D	Neutral	0.497
NOTCH3	Q9UM47-1.2	G114E	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	G114F	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	G114H	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	G114I	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	G114K	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	G114L	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	G114M	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	G114N	Neutral	0.176
NOTCH3	Q9UM47-1.2	G114P	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	G114Q	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	G114R	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	G114S	Neutral	0.188
NOTCH3	Q9UM47-1.2	G114T	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	G114V	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	G114W	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	G114Y	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	P115A	Neutral	0.02
NOTCH3	Q9UM47-1.2	P115C	Neutral	0.314
NOTCH3	Q9UM47-1.2	P115D	Neutral	0.022
NOTCH3	Q9UM47-1.2	P115E	Neutral	0.021
NOTCH3	Q9UM47-1.2	P115F	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	P115G	Neutral	0.08
NOTCH3	Q9UM47-1.2	P115H	Neutral	0.084
NOTCH3	Q9UM47-1.2	P115I	Neutral	0.291
NOTCH3	Q9UM47-1.2	P115K	Neutral	0.019
NOTCH3	Q9UM47-1.2	P115L	Neutral	0.291
NOTCH3	Q9UM47-1.2	P115M	Neutral	0.083
NOTCH3	Q9UM47-1.2	P115N	Neutral	0.092
NOTCH3	Q9UM47-1.2	P115Q	Neutral	0.02
NOTCH3	Q9UM47-1.2	P115R	Neutral	0.076
NOTCH3	Q9UM47-1.2	P115S	Neutral	0.021
NOTCH3	Q9UM47-1.2	P115T	Neutral	0.022
NOTCH3	Q9UM47-1.2	P115V	Neutral	0.088
NOTCH3	Q9UM47-1.2	P115W	Pathogenic	0.618
NOTCH3	Q9UM47-1.2	P115Y	Neutral	0.277
NOTCH3	Q9UM47-1.2	D116A	Neutral	0.118
NOTCH3	Q9UM47-1.2	D116C	Neutral	0.398
NOTCH3	Q9UM47-1.2	D116E	Neutral	0.0
NOTCH3	Q9UM47-1.2	D116F	Neutral	0.364
NOTCH3	Q9UM47-1.2	D116G	Neutral	0.027
NOTCH3	Q9UM47-1.2	D116H	Neutral	0.028
NOTCH3	Q9UM47-1.2	D116I	Neutral	0.374
NOTCH3	Q9UM47-1.2	D116K	Neutral	0.026
NOTCH3	Q9UM47-1.2	D116L	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	D116M	Neutral	0.373
NOTCH3	Q9UM47-1.2	D116N	Neutral	0.002
NOTCH3	Q9UM47-1.2	D116P	Neutral	0.031
NOTCH3	Q9UM47-1.2	D116Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	D116R	Neutral	0.105
NOTCH3	Q9UM47-1.2	D116S	Neutral	0.007
NOTCH3	Q9UM47-1.2	D116T	Neutral	0.031
NOTCH3	Q9UM47-1.2	D116V	Neutral	0.39
NOTCH3	Q9UM47-1.2	D116W	Pathogenic	0.701
NOTCH3	Q9UM47-1.2	D116Y	Neutral	0.357
NOTCH3	Q9UM47-1.2	C117A	Neutral	0.447
NOTCH3	Q9UM47-1.2	C117D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C117E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C117F	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C117G	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C117H	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C117I	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	C117K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C117L	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	C117M	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	C117N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C117P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C117Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C117R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C117S	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C117T	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	C117V	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	C117W	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	C117Y	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	S118A	Neutral	0.002
NOTCH3	Q9UM47-1.2	S118C	Neutral	0.041
NOTCH3	Q9UM47-1.2	S118D	Neutral	0.009
NOTCH3	Q9UM47-1.2	S118E	Neutral	0.008
NOTCH3	Q9UM47-1.2	S118F	Neutral	0.139
NOTCH3	Q9UM47-1.2	S118G	Neutral	0.009
NOTCH3	Q9UM47-1.2	S118H	Neutral	0.036
NOTCH3	Q9UM47-1.2	S118I	Neutral	0.144
NOTCH3	Q9UM47-1.2	S118K	Neutral	0.008
NOTCH3	Q9UM47-1.2	S118L	Neutral	0.144
NOTCH3	Q9UM47-1.2	S118M	Neutral	0.035
NOTCH3	Q9UM47-1.2	S118N	Neutral	0.002
NOTCH3	Q9UM47-1.2	S118P	Neutral	0.04
NOTCH3	Q9UM47-1.2	S118Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	S118R	Neutral	0.032
NOTCH3	Q9UM47-1.2	S118T	Neutral	0.002
NOTCH3	Q9UM47-1.2	S118V	Neutral	0.152
NOTCH3	Q9UM47-1.2	S118W	Neutral	0.398
NOTCH3	Q9UM47-1.2	S118Y	Neutral	0.135
NOTCH3	Q9UM47-1.2	L119A	Neutral	0.019
NOTCH3	Q9UM47-1.2	L119C	Neutral	0.021
NOTCH3	Q9UM47-1.2	L119D	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	L119E	Neutral	0.327
NOTCH3	Q9UM47-1.2	L119F	Neutral	0.005
NOTCH3	Q9UM47-1.2	L119G	Pathogenic	0.635
NOTCH3	Q9UM47-1.2	L119H	Neutral	0.334
NOTCH3	Q9UM47-1.2	L119I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L119K	Neutral	0.098
NOTCH3	Q9UM47-1.2	L119M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L119N	Neutral	0.316
NOTCH3	Q9UM47-1.2	L119P	Neutral	0.309
NOTCH3	Q9UM47-1.2	L119Q	Neutral	0.098
NOTCH3	Q9UM47-1.2	L119R	Neutral	0.094
NOTCH3	Q9UM47-1.2	L119S	Neutral	0.085
NOTCH3	Q9UM47-1.2	L119T	Neutral	0.021
NOTCH3	Q9UM47-1.2	L119V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L119W	Neutral	0.088
NOTCH3	Q9UM47-1.2	L119Y	Neutral	0.022
NOTCH3	Q9UM47-1.2	P120A	Neutral	0.01
NOTCH3	Q9UM47-1.2	P120C	Neutral	0.184
NOTCH3	Q9UM47-1.2	P120D	Neutral	0.011
NOTCH3	Q9UM47-1.2	P120E	Neutral	0.01
NOTCH3	Q9UM47-1.2	P120F	Neutral	0.469
NOTCH3	Q9UM47-1.2	P120G	Neutral	0.041
NOTCH3	Q9UM47-1.2	P120H	Neutral	0.043
NOTCH3	Q9UM47-1.2	P120I	Neutral	0.168
NOTCH3	Q9UM47-1.2	P120K	Neutral	0.009
NOTCH3	Q9UM47-1.2	P120L	Neutral	0.168
NOTCH3	Q9UM47-1.2	P120M	Neutral	0.042
NOTCH3	Q9UM47-1.2	P120N	Neutral	0.047
NOTCH3	Q9UM47-1.2	P120Q	Neutral	0.01
NOTCH3	Q9UM47-1.2	P120R	Neutral	0.039
NOTCH3	Q9UM47-1.2	P120S	Neutral	0.01
NOTCH3	Q9UM47-1.2	P120T	Neutral	0.011
NOTCH3	Q9UM47-1.2	P120V	Neutral	0.045
NOTCH3	Q9UM47-1.2	P120W	Neutral	0.443
NOTCH3	Q9UM47-1.2	P120Y	Neutral	0.158
NOTCH3	Q9UM47-1.2	D121A	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	D121C	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	D121E	Neutral	0.016
NOTCH3	Q9UM47-1.2	D121F	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	D121G	Pathogenic	0.588
NOTCH3	Q9UM47-1.2	D121H	Pathogenic	0.603
NOTCH3	Q9UM47-1.2	D121I	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	D121K	Pathogenic	0.586
NOTCH3	Q9UM47-1.2	D121L	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	D121M	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	D121N	Neutral	0.074
NOTCH3	Q9UM47-1.2	D121P	Pathogenic	0.628
NOTCH3	Q9UM47-1.2	D121Q	Neutral	0.253
NOTCH3	Q9UM47-1.2	D121R	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	D121S	Neutral	0.257
NOTCH3	Q9UM47-1.2	D121T	Pathogenic	0.626
NOTCH3	Q9UM47-1.2	D121V	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	D121W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	D121Y	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	P122A	Neutral	0.111
NOTCH3	Q9UM47-1.2	P122C	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	P122D	Neutral	0.12
NOTCH3	Q9UM47-1.2	P122E	Neutral	0.113
NOTCH3	Q9UM47-1.2	P122F	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	P122G	Neutral	0.346
NOTCH3	Q9UM47-1.2	P122H	Neutral	0.358
NOTCH3	Q9UM47-1.2	P122I	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	P122K	Neutral	0.104
NOTCH3	Q9UM47-1.2	P122L	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	P122M	Neutral	0.352
NOTCH3	Q9UM47-1.2	P122N	Neutral	0.379
NOTCH3	Q9UM47-1.2	P122Q	Neutral	0.111
NOTCH3	Q9UM47-1.2	P122R	Neutral	0.334
NOTCH3	Q9UM47-1.2	P122S	Neutral	0.113
NOTCH3	Q9UM47-1.2	P122T	Neutral	0.119
NOTCH3	Q9UM47-1.2	P122V	Neutral	0.369
NOTCH3	Q9UM47-1.2	P122W	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	P122Y	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	C123A	Neutral	0.449
NOTCH3	Q9UM47-1.2	C123D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C123E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C123F	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	C123G	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C123H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C123I	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	C123K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C123L	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	C123M	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	C123N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C123P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C123Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C123R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C123S	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	C123T	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	C123V	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	C123W	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	C123Y	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	L124A	Neutral	0.107
NOTCH3	Q9UM47-1.2	L124C	Neutral	0.113
NOTCH3	Q9UM47-1.2	L124D	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	L124E	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	L124F	Neutral	0.03
NOTCH3	Q9UM47-1.2	L124G	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	L124H	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	L124I	Neutral	0.002
NOTCH3	Q9UM47-1.2	L124K	Neutral	0.396
NOTCH3	Q9UM47-1.2	L124M	Neutral	0.002
NOTCH3	Q9UM47-1.2	L124N	Pathogenic	0.736
NOTCH3	Q9UM47-1.2	L124P	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	L124Q	Neutral	0.396
NOTCH3	Q9UM47-1.2	L124R	Neutral	0.384
NOTCH3	Q9UM47-1.2	L124S	Neutral	0.358
NOTCH3	Q9UM47-1.2	L124T	Neutral	0.117
NOTCH3	Q9UM47-1.2	L124V	Neutral	0.007
NOTCH3	Q9UM47-1.2	L124W	Neutral	0.367
NOTCH3	Q9UM47-1.2	L124Y	Neutral	0.122
NOTCH3	Q9UM47-1.2	S125A	Neutral	0.05
NOTCH3	Q9UM47-1.2	S125C	Pathogenic	0.518
NOTCH3	Q9UM47-1.2	S125D	Neutral	0.188
NOTCH3	Q9UM47-1.2	S125E	Neutral	0.177
NOTCH3	Q9UM47-1.2	S125F	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	S125G	Neutral	0.183
NOTCH3	Q9UM47-1.2	S125H	Neutral	0.485
NOTCH3	Q9UM47-1.2	S125I	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	S125K	Neutral	0.163
NOTCH3	Q9UM47-1.2	S125L	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	S125M	Neutral	0.482
NOTCH3	Q9UM47-1.2	S125N	Neutral	0.047
NOTCH3	Q9UM47-1.2	S125P	Pathogenic	0.513
NOTCH3	Q9UM47-1.2	S125Q	Neutral	0.174
NOTCH3	Q9UM47-1.2	S125R	Neutral	0.458
NOTCH3	Q9UM47-1.2	S125T	Neutral	0.048
NOTCH3	Q9UM47-1.2	S125V	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	S125W	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	S125Y	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	S126A	Neutral	0.002
NOTCH3	Q9UM47-1.2	S126C	Neutral	0.045
NOTCH3	Q9UM47-1.2	S126D	Neutral	0.01
NOTCH3	Q9UM47-1.2	S126E	Neutral	0.009
NOTCH3	Q9UM47-1.2	S126F	Neutral	0.151
NOTCH3	Q9UM47-1.2	S126G	Neutral	0.01
NOTCH3	Q9UM47-1.2	S126H	Neutral	0.04
NOTCH3	Q9UM47-1.2	S126I	Neutral	0.157
NOTCH3	Q9UM47-1.2	S126K	Neutral	0.008
NOTCH3	Q9UM47-1.2	S126L	Neutral	0.157
NOTCH3	Q9UM47-1.2	S126M	Neutral	0.039
NOTCH3	Q9UM47-1.2	S126N	Neutral	0.002
NOTCH3	Q9UM47-1.2	S126P	Neutral	0.044
NOTCH3	Q9UM47-1.2	S126Q	Neutral	0.009
NOTCH3	Q9UM47-1.2	S126R	Neutral	0.036
NOTCH3	Q9UM47-1.2	S126T	Neutral	0.002
NOTCH3	Q9UM47-1.2	S126V	Neutral	0.166
NOTCH3	Q9UM47-1.2	S126W	Neutral	0.422
NOTCH3	Q9UM47-1.2	S126Y	Neutral	0.147
NOTCH3	Q9UM47-1.2	P127A	Pathogenic	0.652
NOTCH3	Q9UM47-1.2	P127C	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	P127D	Pathogenic	0.673
NOTCH3	Q9UM47-1.2	P127E	Pathogenic	0.657
NOTCH3	Q9UM47-1.2	P127F	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P127G	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	P127H	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	P127I	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	P127K	Pathogenic	0.635
NOTCH3	Q9UM47-1.2	P127L	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	P127M	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	P127N	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	P127Q	Pathogenic	0.652
NOTCH3	Q9UM47-1.2	P127R	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	P127S	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	P127T	Pathogenic	0.669
NOTCH3	Q9UM47-1.2	P127V	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	P127W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	P127Y	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	C128A	Neutral	0.446
NOTCH3	Q9UM47-1.2	C128D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C128E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C128F	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C128G	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C128H	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C128I	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	C128K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C128L	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	C128M	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	C128N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C128P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C128Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C128R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C128S	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C128T	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	C128V	Pathogenic	0.785
NOTCH3	Q9UM47-1.2	C128W	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	C128Y	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	A129C	Neutral	0.141
NOTCH3	Q9UM47-1.2	A129D	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	A129E	Neutral	0.406
NOTCH3	Q9UM47-1.2	A129F	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	A129G	Neutral	0.14
NOTCH3	Q9UM47-1.2	A129H	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	A129I	Neutral	0.393
NOTCH3	Q9UM47-1.2	A129K	Neutral	0.382
NOTCH3	Q9UM47-1.2	A129L	Neutral	0.393
NOTCH3	Q9UM47-1.2	A129M	Neutral	0.392
NOTCH3	Q9UM47-1.2	A129N	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	A129P	Neutral	0.422
NOTCH3	Q9UM47-1.2	A129Q	Neutral	0.4
NOTCH3	Q9UM47-1.2	A129R	Neutral	0.371
NOTCH3	Q9UM47-1.2	A129S	Neutral	0.036
NOTCH3	Q9UM47-1.2	A129T	Neutral	0.137
NOTCH3	Q9UM47-1.2	A129V	Neutral	0.132
NOTCH3	Q9UM47-1.2	A129W	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	A129Y	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	H130A	Neutral	0.468
NOTCH3	Q9UM47-1.2	H130C	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	H130D	Neutral	0.176
NOTCH3	Q9UM47-1.2	H130E	Neutral	0.048
NOTCH3	Q9UM47-1.2	H130F	Neutral	0.182
NOTCH3	Q9UM47-1.2	H130G	Neutral	0.449
NOTCH3	Q9UM47-1.2	H130I	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	H130K	Neutral	0.181
NOTCH3	Q9UM47-1.2	H130L	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	H130M	Pathogenic	0.513
NOTCH3	Q9UM47-1.2	H130N	Neutral	0.01
NOTCH3	Q9UM47-1.2	H130P	Neutral	0.491
NOTCH3	Q9UM47-1.2	H130Q	Neutral	0.048
NOTCH3	Q9UM47-1.2	H130R	Neutral	0.044
NOTCH3	Q9UM47-1.2	H130S	Neutral	0.165
NOTCH3	Q9UM47-1.2	H130T	Neutral	0.493
NOTCH3	Q9UM47-1.2	H130V	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	H130W	Neutral	0.477
NOTCH3	Q9UM47-1.2	H130Y	Neutral	0.002
NOTCH3	Q9UM47-1.2	G131A	Neutral	0.151
NOTCH3	Q9UM47-1.2	G131C	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	G131D	Neutral	0.425
NOTCH3	Q9UM47-1.2	G131E	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	G131F	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	G131H	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	G131I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	G131K	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	G131L	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	G131M	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	G131N	Neutral	0.137
NOTCH3	Q9UM47-1.2	G131P	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	G131Q	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	G131R	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	G131S	Neutral	0.148
NOTCH3	Q9UM47-1.2	G131T	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	G131V	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	G131W	Pathogenic	0.721
NOTCH3	Q9UM47-1.2	G131Y	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	A132C	Neutral	0.016
NOTCH3	Q9UM47-1.2	A132D	Neutral	0.247
NOTCH3	Q9UM47-1.2	A132E	Neutral	0.063
NOTCH3	Q9UM47-1.2	A132F	Neutral	0.218
NOTCH3	Q9UM47-1.2	A132G	Neutral	0.016
NOTCH3	Q9UM47-1.2	A132H	Neutral	0.227
NOTCH3	Q9UM47-1.2	A132I	Neutral	0.06
NOTCH3	Q9UM47-1.2	A132K	Neutral	0.058
NOTCH3	Q9UM47-1.2	A132L	Neutral	0.06
NOTCH3	Q9UM47-1.2	A132M	Neutral	0.06
NOTCH3	Q9UM47-1.2	A132N	Neutral	0.244
NOTCH3	Q9UM47-1.2	A132P	Neutral	0.067
NOTCH3	Q9UM47-1.2	A132Q	Neutral	0.062
NOTCH3	Q9UM47-1.2	A132R	Neutral	0.055
NOTCH3	Q9UM47-1.2	A132S	Neutral	0.004
NOTCH3	Q9UM47-1.2	A132T	Neutral	0.015
NOTCH3	Q9UM47-1.2	A132V	Neutral	0.015
NOTCH3	Q9UM47-1.2	A132W	Pathogenic	0.533
NOTCH3	Q9UM47-1.2	A132Y	Neutral	0.213
NOTCH3	Q9UM47-1.2	R133A	Neutral	0.055
NOTCH3	Q9UM47-1.2	R133C	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	R133D	Neutral	0.224
NOTCH3	Q9UM47-1.2	R133E	Neutral	0.015
NOTCH3	Q9UM47-1.2	R133F	Pathogenic	0.614
NOTCH3	Q9UM47-1.2	R133G	Neutral	0.198
NOTCH3	Q9UM47-1.2	R133H	Neutral	0.015
NOTCH3	Q9UM47-1.2	R133I	Pathogenic	0.604
NOTCH3	Q9UM47-1.2	R133K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R133L	Neutral	0.251
NOTCH3	Q9UM47-1.2	R133M	Neutral	0.068
NOTCH3	Q9UM47-1.2	R133N	Neutral	0.014
NOTCH3	Q9UM47-1.2	R133P	Neutral	0.226
NOTCH3	Q9UM47-1.2	R133Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R133S	Neutral	0.056
NOTCH3	Q9UM47-1.2	R133T	Neutral	0.061
NOTCH3	Q9UM47-1.2	R133V	Pathogenic	0.585
NOTCH3	Q9UM47-1.2	R133W	Pathogenic	0.613
NOTCH3	Q9UM47-1.2	R133Y	Neutral	0.262
NOTCH3	Q9UM47-1.2	C134A	Neutral	0.459
NOTCH3	Q9UM47-1.2	C134D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C134E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C134F	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	C134G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C134H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C134I	Pathogenic	0.782
NOTCH3	Q9UM47-1.2	C134K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C134L	Pathogenic	0.782
NOTCH3	Q9UM47-1.2	C134M	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	C134N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C134P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C134Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C134R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C134S	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	C134T	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C134V	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	C134W	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	C134Y	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	S135A	Neutral	0.002
NOTCH3	Q9UM47-1.2	S135C	Neutral	0.048
NOTCH3	Q9UM47-1.2	S135D	Neutral	0.011
NOTCH3	Q9UM47-1.2	S135E	Neutral	0.01
NOTCH3	Q9UM47-1.2	S135F	Neutral	0.16
NOTCH3	Q9UM47-1.2	S135G	Neutral	0.01
NOTCH3	Q9UM47-1.2	S135H	Neutral	0.042
NOTCH3	Q9UM47-1.2	S135I	Neutral	0.166
NOTCH3	Q9UM47-1.2	S135K	Neutral	0.009
NOTCH3	Q9UM47-1.2	S135L	Neutral	0.166
NOTCH3	Q9UM47-1.2	S135M	Neutral	0.042
NOTCH3	Q9UM47-1.2	S135N	Neutral	0.002
NOTCH3	Q9UM47-1.2	S135P	Neutral	0.047
NOTCH3	Q9UM47-1.2	S135Q	Neutral	0.01
NOTCH3	Q9UM47-1.2	S135R	Neutral	0.038
NOTCH3	Q9UM47-1.2	S135T	Neutral	0.002
NOTCH3	Q9UM47-1.2	S135V	Neutral	0.176
NOTCH3	Q9UM47-1.2	S135W	Neutral	0.439
NOTCH3	Q9UM47-1.2	S135Y	Neutral	0.156
NOTCH3	Q9UM47-1.2	V136A	Neutral	0.012
NOTCH3	Q9UM47-1.2	V136C	Neutral	0.056
NOTCH3	Q9UM47-1.2	V136D	Pathogenic	0.561
NOTCH3	Q9UM47-1.2	V136E	Neutral	0.226
NOTCH3	Q9UM47-1.2	V136F	Neutral	0.054
NOTCH3	Q9UM47-1.2	V136G	Pathogenic	0.519
NOTCH3	Q9UM47-1.2	V136H	Pathogenic	0.56
NOTCH3	Q9UM47-1.2	V136I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V136K	Neutral	0.209
NOTCH3	Q9UM47-1.2	V136L	Neutral	0.003
NOTCH3	Q9UM47-1.2	V136M	Neutral	0.003
NOTCH3	Q9UM47-1.2	V136N	Pathogenic	0.566
NOTCH3	Q9UM47-1.2	V136P	Neutral	0.217
NOTCH3	Q9UM47-1.2	V136Q	Neutral	0.222
NOTCH3	Q9UM47-1.2	V136R	Pathogenic	0.534
NOTCH3	Q9UM47-1.2	V136S	Neutral	0.207
NOTCH3	Q9UM47-1.2	V136T	Neutral	0.013
NOTCH3	Q9UM47-1.2	V136W	Pathogenic	0.517
NOTCH3	Q9UM47-1.2	V136Y	Neutral	0.053
NOTCH3	Q9UM47-1.2	G137A	Neutral	0.001
NOTCH3	Q9UM47-1.2	G137C	Neutral	0.08
NOTCH3	Q9UM47-1.2	G137D	Neutral	0.004
NOTCH3	Q9UM47-1.2	G137E	Neutral	0.017
NOTCH3	Q9UM47-1.2	G137F	Neutral	0.068
NOTCH3	Q9UM47-1.2	G137H	Neutral	0.016
NOTCH3	Q9UM47-1.2	G137I	Neutral	0.256
NOTCH3	Q9UM47-1.2	G137K	Neutral	0.016
NOTCH3	Q9UM47-1.2	G137L	Neutral	0.256
NOTCH3	Q9UM47-1.2	G137M	Neutral	0.07
NOTCH3	Q9UM47-1.2	G137N	Neutral	0.001
NOTCH3	Q9UM47-1.2	G137P	Neutral	0.018
NOTCH3	Q9UM47-1.2	G137Q	Neutral	0.017
NOTCH3	Q9UM47-1.2	G137R	Neutral	0.015
NOTCH3	Q9UM47-1.2	G137S	Neutral	0.001
NOTCH3	Q9UM47-1.2	G137T	Neutral	0.018
NOTCH3	Q9UM47-1.2	G137V	Neutral	0.075
NOTCH3	Q9UM47-1.2	G137W	Neutral	0.014
NOTCH3	Q9UM47-1.2	G137Y	Neutral	0.066
NOTCH3	Q9UM47-1.2	P138A	Neutral	0.01
NOTCH3	Q9UM47-1.2	P138C	Neutral	0.189
NOTCH3	Q9UM47-1.2	P138D	Neutral	0.011
NOTCH3	Q9UM47-1.2	P138E	Neutral	0.011
NOTCH3	Q9UM47-1.2	P138F	Neutral	0.477
NOTCH3	Q9UM47-1.2	P138G	Neutral	0.042
NOTCH3	Q9UM47-1.2	P138H	Neutral	0.045
NOTCH3	Q9UM47-1.2	P138I	Neutral	0.173
NOTCH3	Q9UM47-1.2	P138K	Neutral	0.01
NOTCH3	Q9UM47-1.2	P138L	Neutral	0.173
NOTCH3	Q9UM47-1.2	P138M	Neutral	0.044
NOTCH3	Q9UM47-1.2	P138N	Neutral	0.049
NOTCH3	Q9UM47-1.2	P138Q	Neutral	0.01
NOTCH3	Q9UM47-1.2	P138R	Neutral	0.04
NOTCH3	Q9UM47-1.2	P138S	Neutral	0.011
NOTCH3	Q9UM47-1.2	P138T	Neutral	0.011
NOTCH3	Q9UM47-1.2	P138V	Neutral	0.047
NOTCH3	Q9UM47-1.2	P138W	Neutral	0.451
NOTCH3	Q9UM47-1.2	P138Y	Neutral	0.163
NOTCH3	Q9UM47-1.2	D139A	Neutral	0.123
NOTCH3	Q9UM47-1.2	D139C	Neutral	0.409
NOTCH3	Q9UM47-1.2	D139E	Neutral	0.0
NOTCH3	Q9UM47-1.2	D139F	Neutral	0.375
NOTCH3	Q9UM47-1.2	D139G	Neutral	0.028
NOTCH3	Q9UM47-1.2	D139H	Neutral	0.03
NOTCH3	Q9UM47-1.2	D139I	Neutral	0.385
NOTCH3	Q9UM47-1.2	D139K	Neutral	0.028
NOTCH3	Q9UM47-1.2	D139L	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	D139M	Neutral	0.384
NOTCH3	Q9UM47-1.2	D139N	Neutral	0.002
NOTCH3	Q9UM47-1.2	D139P	Neutral	0.033
NOTCH3	Q9UM47-1.2	D139Q	Neutral	0.007
NOTCH3	Q9UM47-1.2	D139R	Neutral	0.109
NOTCH3	Q9UM47-1.2	D139S	Neutral	0.007
NOTCH3	Q9UM47-1.2	D139T	Neutral	0.032
NOTCH3	Q9UM47-1.2	D139V	Neutral	0.401
NOTCH3	Q9UM47-1.2	D139W	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	D139Y	Neutral	0.368
NOTCH3	Q9UM47-1.2	G140A	Neutral	0.003
NOTCH3	Q9UM47-1.2	G140C	Neutral	0.224
NOTCH3	Q9UM47-1.2	G140D	Neutral	0.013
NOTCH3	Q9UM47-1.2	G140E	Neutral	0.055
NOTCH3	Q9UM47-1.2	G140F	Neutral	0.194
NOTCH3	Q9UM47-1.2	G140H	Neutral	0.053
NOTCH3	Q9UM47-1.2	G140I	Pathogenic	0.534
NOTCH3	Q9UM47-1.2	G140K	Neutral	0.05
NOTCH3	Q9UM47-1.2	G140L	Pathogenic	0.534
NOTCH3	Q9UM47-1.2	G140M	Neutral	0.2
NOTCH3	Q9UM47-1.2	G140N	Neutral	0.003
NOTCH3	Q9UM47-1.2	G140P	Neutral	0.059
NOTCH3	Q9UM47-1.2	G140Q	Neutral	0.054
NOTCH3	Q9UM47-1.2	G140R	Neutral	0.048
NOTCH3	Q9UM47-1.2	G140S	Neutral	0.003
NOTCH3	Q9UM47-1.2	G140T	Neutral	0.058
NOTCH3	Q9UM47-1.2	G140V	Neutral	0.212
NOTCH3	Q9UM47-1.2	G140W	Neutral	0.046
NOTCH3	Q9UM47-1.2	G140Y	Neutral	0.19
NOTCH3	Q9UM47-1.2	R141A	Neutral	0.03
NOTCH3	Q9UM47-1.2	R141C	Neutral	0.407
NOTCH3	Q9UM47-1.2	R141D	Neutral	0.132
NOTCH3	Q9UM47-1.2	R141E	Neutral	0.008
NOTCH3	Q9UM47-1.2	R141F	Neutral	0.455
NOTCH3	Q9UM47-1.2	R141G	Neutral	0.115
NOTCH3	Q9UM47-1.2	R141H	Neutral	0.008
NOTCH3	Q9UM47-1.2	R141I	Neutral	0.445
NOTCH3	Q9UM47-1.2	R141K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R141L	Neutral	0.15
NOTCH3	Q9UM47-1.2	R141M	Neutral	0.037
NOTCH3	Q9UM47-1.2	R141N	Neutral	0.007
NOTCH3	Q9UM47-1.2	R141P	Neutral	0.133
NOTCH3	Q9UM47-1.2	R141Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	R141S	Neutral	0.03
NOTCH3	Q9UM47-1.2	R141T	Neutral	0.033
NOTCH3	Q9UM47-1.2	R141V	Neutral	0.426
NOTCH3	Q9UM47-1.2	R141W	Neutral	0.454
NOTCH3	Q9UM47-1.2	R141Y	Neutral	0.157
NOTCH3	Q9UM47-1.2	F142A	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	F142C	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	F142D	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	F142E	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	F142G	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	F142H	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	F142I	Neutral	0.225
NOTCH3	Q9UM47-1.2	F142K	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	F142L	Neutral	0.225
NOTCH3	Q9UM47-1.2	F142M	Neutral	0.226
NOTCH3	Q9UM47-1.2	F142N	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	F142P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	F142Q	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	F142R	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	F142S	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	F142T	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	F142V	Pathogenic	0.552
NOTCH3	Q9UM47-1.2	F142W	Neutral	0.057
NOTCH3	Q9UM47-1.2	F142Y	Neutral	0.003
NOTCH3	Q9UM47-1.2	L143A	Neutral	0.002
NOTCH3	Q9UM47-1.2	L143C	Neutral	0.002
NOTCH3	Q9UM47-1.2	L143D	Neutral	0.169
NOTCH3	Q9UM47-1.2	L143E	Neutral	0.046
NOTCH3	Q9UM47-1.2	L143F	Neutral	0.001
NOTCH3	Q9UM47-1.2	L143G	Neutral	0.146
NOTCH3	Q9UM47-1.2	L143H	Neutral	0.047
NOTCH3	Q9UM47-1.2	L143I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L143K	Neutral	0.011
NOTCH3	Q9UM47-1.2	L143M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L143N	Neutral	0.043
NOTCH3	Q9UM47-1.2	L143P	Neutral	0.042
NOTCH3	Q9UM47-1.2	L143Q	Neutral	0.011
NOTCH3	Q9UM47-1.2	L143R	Neutral	0.01
NOTCH3	Q9UM47-1.2	L143S	Neutral	0.009
NOTCH3	Q9UM47-1.2	L143T	Neutral	0.002
NOTCH3	Q9UM47-1.2	L143V	Neutral	0.0
NOTCH3	Q9UM47-1.2	L143W	Neutral	0.009
NOTCH3	Q9UM47-1.2	L143Y	Neutral	0.002
NOTCH3	Q9UM47-1.2	C144A	Neutral	0.448
NOTCH3	Q9UM47-1.2	C144D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C144E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C144F	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C144G	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C144H	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C144I	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	C144K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C144L	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	C144M	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	C144N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C144P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C144Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C144R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C144S	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	C144T	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	C144V	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	C144W	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	C144Y	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	S145A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S145C	Neutral	0.023
NOTCH3	Q9UM47-1.2	S145D	Neutral	0.005
NOTCH3	Q9UM47-1.2	S145E	Neutral	0.005
NOTCH3	Q9UM47-1.2	S145F	Neutral	0.084
NOTCH3	Q9UM47-1.2	S145G	Neutral	0.005
NOTCH3	Q9UM47-1.2	S145H	Neutral	0.021
NOTCH3	Q9UM47-1.2	S145I	Neutral	0.087
NOTCH3	Q9UM47-1.2	S145K	Neutral	0.004
NOTCH3	Q9UM47-1.2	S145L	Neutral	0.087
NOTCH3	Q9UM47-1.2	S145M	Neutral	0.02
NOTCH3	Q9UM47-1.2	S145N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S145P	Neutral	0.023
NOTCH3	Q9UM47-1.2	S145Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	S145R	Neutral	0.019
NOTCH3	Q9UM47-1.2	S145T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S145V	Neutral	0.092
NOTCH3	Q9UM47-1.2	S145W	Neutral	0.272
NOTCH3	Q9UM47-1.2	S145Y	Neutral	0.081
NOTCH3	Q9UM47-1.2	C146A	Neutral	0.45
NOTCH3	Q9UM47-1.2	C146D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C146E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C146F	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	C146G	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C146H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C146I	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	C146K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C146L	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	C146M	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	C146N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C146P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C146Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C146R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C146S	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	C146T	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	C146V	Pathogenic	0.788
NOTCH3	Q9UM47-1.2	C146W	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	C146Y	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	P147A	Neutral	0.144
NOTCH3	Q9UM47-1.2	P147C	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	P147D	Neutral	0.156
NOTCH3	Q9UM47-1.2	P147E	Neutral	0.147
NOTCH3	Q9UM47-1.2	P147F	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	P147G	Neutral	0.416
NOTCH3	Q9UM47-1.2	P147H	Neutral	0.429
NOTCH3	Q9UM47-1.2	P147I	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	P147K	Neutral	0.135
NOTCH3	Q9UM47-1.2	P147L	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	P147M	Neutral	0.423
NOTCH3	Q9UM47-1.2	P147N	Neutral	0.452
NOTCH3	Q9UM47-1.2	P147Q	Neutral	0.144
NOTCH3	Q9UM47-1.2	P147R	Neutral	0.403
NOTCH3	Q9UM47-1.2	P147S	Neutral	0.147
NOTCH3	Q9UM47-1.2	P147T	Neutral	0.154
NOTCH3	Q9UM47-1.2	P147V	Neutral	0.441
NOTCH3	Q9UM47-1.2	P147W	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	P147Y	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	P148A	Neutral	0.138
NOTCH3	Q9UM47-1.2	P148C	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	P148D	Neutral	0.149
NOTCH3	Q9UM47-1.2	P148E	Neutral	0.14
NOTCH3	Q9UM47-1.2	P148F	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	P148G	Neutral	0.404
NOTCH3	Q9UM47-1.2	P148H	Neutral	0.417
NOTCH3	Q9UM47-1.2	P148I	Pathogenic	0.761
NOTCH3	Q9UM47-1.2	P148K	Neutral	0.129
NOTCH3	Q9UM47-1.2	P148L	Pathogenic	0.761
NOTCH3	Q9UM47-1.2	P148M	Neutral	0.411
NOTCH3	Q9UM47-1.2	P148N	Neutral	0.439
NOTCH3	Q9UM47-1.2	P148Q	Neutral	0.138
NOTCH3	Q9UM47-1.2	P148R	Neutral	0.391
NOTCH3	Q9UM47-1.2	P148S	Neutral	0.141
NOTCH3	Q9UM47-1.2	P148T	Neutral	0.147
NOTCH3	Q9UM47-1.2	P148V	Neutral	0.429
NOTCH3	Q9UM47-1.2	P148W	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	P148Y	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	G149A	Neutral	0.082
NOTCH3	Q9UM47-1.2	G149C	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	G149D	Neutral	0.271
NOTCH3	Q9UM47-1.2	G149E	Pathogenic	0.612
NOTCH3	Q9UM47-1.2	G149F	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	G149H	Pathogenic	0.603
NOTCH3	Q9UM47-1.2	G149I	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	G149K	Pathogenic	0.589
NOTCH3	Q9UM47-1.2	G149L	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	G149M	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	G149N	Neutral	0.074
NOTCH3	Q9UM47-1.2	G149P	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	G149Q	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	G149R	Pathogenic	0.577
NOTCH3	Q9UM47-1.2	G149S	Neutral	0.08
NOTCH3	Q9UM47-1.2	G149T	Pathogenic	0.626
NOTCH3	Q9UM47-1.2	G149V	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	G149W	Pathogenic	0.565
NOTCH3	Q9UM47-1.2	G149Y	Pathogenic	0.864
NOTCH3	Q9UM47-1.2	Y150A	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	Y150C	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	Y150D	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	Y150E	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	Y150F	Neutral	0.002
NOTCH3	Q9UM47-1.2	Y150G	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	Y150H	Neutral	0.009
NOTCH3	Q9UM47-1.2	Y150I	Neutral	0.464
NOTCH3	Q9UM47-1.2	Y150K	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	Y150L	Neutral	0.464
NOTCH3	Q9UM47-1.2	Y150M	Neutral	0.463
NOTCH3	Q9UM47-1.2	Y150N	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	Y150P	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	Y150Q	Neutral	0.455
NOTCH3	Q9UM47-1.2	Y150R	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	Y150S	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	Y150T	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	Y150V	Neutral	0.445
NOTCH3	Q9UM47-1.2	Y150W	Neutral	0.009
NOTCH3	Q9UM47-1.2	Q151A	Neutral	0.047
NOTCH3	Q9UM47-1.2	Q151C	Pathogenic	0.524
NOTCH3	Q9UM47-1.2	Q151D	Neutral	0.012
NOTCH3	Q9UM47-1.2	Q151E	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q151F	Pathogenic	0.532
NOTCH3	Q9UM47-1.2	Q151G	Neutral	0.171
NOTCH3	Q9UM47-1.2	Q151H	Neutral	0.013
NOTCH3	Q9UM47-1.2	Q151I	Pathogenic	0.543
NOTCH3	Q9UM47-1.2	Q151K	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q151L	Neutral	0.207
NOTCH3	Q9UM47-1.2	Q151M	Neutral	0.012
NOTCH3	Q9UM47-1.2	Q151N	Neutral	0.012
NOTCH3	Q9UM47-1.2	Q151P	Neutral	0.051
NOTCH3	Q9UM47-1.2	Q151R	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q151S	Neutral	0.011
NOTCH3	Q9UM47-1.2	Q151T	Neutral	0.051
NOTCH3	Q9UM47-1.2	Q151V	Neutral	0.207
NOTCH3	Q9UM47-1.2	Q151W	Neutral	0.184
NOTCH3	Q9UM47-1.2	Q151Y	Neutral	0.051
NOTCH3	Q9UM47-1.2	G152A	Neutral	0.178
NOTCH3	Q9UM47-1.2	G152C	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	G152D	Neutral	0.474
NOTCH3	Q9UM47-1.2	G152E	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	G152F	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	G152H	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	G152I	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	G152K	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	G152L	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	G152M	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	G152N	Neutral	0.162
NOTCH3	Q9UM47-1.2	G152P	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	G152Q	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	G152R	Pathogenic	0.767
NOTCH3	Q9UM47-1.2	G152S	Neutral	0.174
NOTCH3	Q9UM47-1.2	G152T	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	G152V	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	G152W	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	G152Y	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	R153A	Neutral	0.029
NOTCH3	Q9UM47-1.2	R153C	Neutral	0.402
NOTCH3	Q9UM47-1.2	R153D	Neutral	0.129
NOTCH3	Q9UM47-1.2	R153E	Neutral	0.008
NOTCH3	Q9UM47-1.2	R153F	Neutral	0.45
NOTCH3	Q9UM47-1.2	R153G	Neutral	0.112
NOTCH3	Q9UM47-1.2	R153H	Neutral	0.008
NOTCH3	Q9UM47-1.2	R153I	Neutral	0.439
NOTCH3	Q9UM47-1.2	R153K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R153L	Neutral	0.147
NOTCH3	Q9UM47-1.2	R153M	Neutral	0.036
NOTCH3	Q9UM47-1.2	R153N	Neutral	0.007
NOTCH3	Q9UM47-1.2	R153P	Neutral	0.13
NOTCH3	Q9UM47-1.2	R153Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	R153S	Neutral	0.03
NOTCH3	Q9UM47-1.2	R153T	Neutral	0.032
NOTCH3	Q9UM47-1.2	R153V	Neutral	0.42
NOTCH3	Q9UM47-1.2	R153W	Neutral	0.449
NOTCH3	Q9UM47-1.2	R153Y	Neutral	0.154
NOTCH3	Q9UM47-1.2	S154A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S154C	Neutral	0.012
NOTCH3	Q9UM47-1.2	S154D	Neutral	0.003
NOTCH3	Q9UM47-1.2	S154E	Neutral	0.002
NOTCH3	Q9UM47-1.2	S154F	Neutral	0.044
NOTCH3	Q9UM47-1.2	S154G	Neutral	0.003
NOTCH3	Q9UM47-1.2	S154H	Neutral	0.011
NOTCH3	Q9UM47-1.2	S154I	Neutral	0.046
NOTCH3	Q9UM47-1.2	S154K	Neutral	0.002
NOTCH3	Q9UM47-1.2	S154L	Neutral	0.046
NOTCH3	Q9UM47-1.2	S154M	Neutral	0.01
NOTCH3	Q9UM47-1.2	S154N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S154P	Neutral	0.012
NOTCH3	Q9UM47-1.2	S154Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	S154R	Neutral	0.01
NOTCH3	Q9UM47-1.2	S154T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S154V	Neutral	0.049
NOTCH3	Q9UM47-1.2	S154W	Neutral	0.16
NOTCH3	Q9UM47-1.2	S154Y	Neutral	0.043
NOTCH3	Q9UM47-1.2	C155A	Neutral	0.415
NOTCH3	Q9UM47-1.2	C155D	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C155E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C155F	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	C155G	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	C155H	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C155I	Pathogenic	0.75
NOTCH3	Q9UM47-1.2	C155K	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	C155L	Pathogenic	0.75
NOTCH3	Q9UM47-1.2	C155M	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	C155N	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C155P	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C155Q	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C155R	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	C155S	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	C155T	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	C155V	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	C155W	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	C155Y	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	R156A	Neutral	0.096
NOTCH3	Q9UM47-1.2	R156C	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	R156D	Neutral	0.343
NOTCH3	Q9UM47-1.2	R156E	Neutral	0.026
NOTCH3	Q9UM47-1.2	R156F	Pathogenic	0.742
NOTCH3	Q9UM47-1.2	R156G	Neutral	0.308
NOTCH3	Q9UM47-1.2	R156H	Neutral	0.027
NOTCH3	Q9UM47-1.2	R156I	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	R156K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R156L	Neutral	0.377
NOTCH3	Q9UM47-1.2	R156M	Neutral	0.117
NOTCH3	Q9UM47-1.2	R156N	Neutral	0.025
NOTCH3	Q9UM47-1.2	R156P	Neutral	0.345
NOTCH3	Q9UM47-1.2	R156Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	R156S	Neutral	0.097
NOTCH3	Q9UM47-1.2	R156T	Neutral	0.104
NOTCH3	Q9UM47-1.2	R156V	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	R156W	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	R156Y	Neutral	0.391
NOTCH3	Q9UM47-1.2	S157A	Neutral	0.0
NOTCH3	Q9UM47-1.2	S157C	Neutral	0.009
NOTCH3	Q9UM47-1.2	S157D	Neutral	0.002
NOTCH3	Q9UM47-1.2	S157E	Neutral	0.002
NOTCH3	Q9UM47-1.2	S157F	Neutral	0.034
NOTCH3	Q9UM47-1.2	S157G	Neutral	0.002
NOTCH3	Q9UM47-1.2	S157H	Neutral	0.008
NOTCH3	Q9UM47-1.2	S157I	Neutral	0.036
NOTCH3	Q9UM47-1.2	S157K	Neutral	0.002
NOTCH3	Q9UM47-1.2	S157L	Neutral	0.035
NOTCH3	Q9UM47-1.2	S157M	Neutral	0.008
NOTCH3	Q9UM47-1.2	S157N	Neutral	0.0
NOTCH3	Q9UM47-1.2	S157P	Neutral	0.009
NOTCH3	Q9UM47-1.2	S157Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	S157R	Neutral	0.007
NOTCH3	Q9UM47-1.2	S157T	Neutral	0.0
NOTCH3	Q9UM47-1.2	S157V	Neutral	0.038
NOTCH3	Q9UM47-1.2	S157W	Neutral	0.126
NOTCH3	Q9UM47-1.2	S157Y	Neutral	0.033
NOTCH3	Q9UM47-1.2	D158A	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	D158C	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	D158E	Neutral	0.022
NOTCH3	Q9UM47-1.2	D158F	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	D158G	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	D158H	Pathogenic	0.675
NOTCH3	Q9UM47-1.2	D158I	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	D158K	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	D158L	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D158M	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	D158N	Neutral	0.098
NOTCH3	Q9UM47-1.2	D158P	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	D158Q	Neutral	0.316
NOTCH3	Q9UM47-1.2	D158R	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	D158S	Neutral	0.32
NOTCH3	Q9UM47-1.2	D158T	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	D158V	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	D158W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	D158Y	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	V159A	Neutral	0.121
NOTCH3	Q9UM47-1.2	V159C	Neutral	0.4
NOTCH3	Q9UM47-1.2	V159D	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	V159E	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	V159F	Neutral	0.391
NOTCH3	Q9UM47-1.2	V159G	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	V159H	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	V159I	Neutral	0.002
NOTCH3	Q9UM47-1.2	V159K	Pathogenic	0.747
NOTCH3	Q9UM47-1.2	V159L	Neutral	0.031
NOTCH3	Q9UM47-1.2	V159M	Neutral	0.031
NOTCH3	Q9UM47-1.2	V159N	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	V159P	Pathogenic	0.756
NOTCH3	Q9UM47-1.2	V159Q	Pathogenic	0.761
NOTCH3	Q9UM47-1.2	V159R	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	V159S	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	V159T	Neutral	0.132
NOTCH3	Q9UM47-1.2	V159W	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	V159Y	Neutral	0.385
NOTCH3	Q9UM47-1.2	D160A	Neutral	0.319
NOTCH3	Q9UM47-1.2	D160C	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	D160E	Neutral	0.001
NOTCH3	Q9UM47-1.2	D160F	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	D160G	Neutral	0.087
NOTCH3	Q9UM47-1.2	D160H	Neutral	0.092
NOTCH3	Q9UM47-1.2	D160I	Pathogenic	0.675
NOTCH3	Q9UM47-1.2	D160K	Neutral	0.086
NOTCH3	Q9UM47-1.2	D160L	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	D160M	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	D160N	Neutral	0.005
NOTCH3	Q9UM47-1.2	D160P	Neutral	0.101
NOTCH3	Q9UM47-1.2	D160Q	Neutral	0.022
NOTCH3	Q9UM47-1.2	D160R	Neutral	0.29
NOTCH3	Q9UM47-1.2	D160S	Neutral	0.023
NOTCH3	Q9UM47-1.2	D160T	Neutral	0.101
NOTCH3	Q9UM47-1.2	D160V	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	D160W	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	D160Y	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	E161A	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	E161C	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	E161D	Neutral	0.034
NOTCH3	Q9UM47-1.2	E161F	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	E161G	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	E161H	Neutral	0.432
NOTCH3	Q9UM47-1.2	E161I	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	E161K	Neutral	0.135
NOTCH3	Q9UM47-1.2	E161L	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	E161M	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	E161N	Neutral	0.427
NOTCH3	Q9UM47-1.2	E161P	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	E161Q	Neutral	0.036
NOTCH3	Q9UM47-1.2	E161R	Neutral	0.403
NOTCH3	Q9UM47-1.2	E161S	Neutral	0.407
NOTCH3	Q9UM47-1.2	E161T	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	E161V	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	E161W	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	E161Y	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	C162A	Neutral	0.42
NOTCH3	Q9UM47-1.2	C162D	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C162E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C162F	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	C162G	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C162H	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C162I	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	C162K	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	C162L	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	C162M	Pathogenic	0.753
NOTCH3	Q9UM47-1.2	C162N	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C162P	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C162Q	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C162R	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	C162S	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	C162T	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	C162V	Pathogenic	0.767
NOTCH3	Q9UM47-1.2	C162W	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	C162Y	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	R163A	Neutral	0.033
NOTCH3	Q9UM47-1.2	R163C	Neutral	0.433
NOTCH3	Q9UM47-1.2	R163D	Neutral	0.144
NOTCH3	Q9UM47-1.2	R163E	Neutral	0.009
NOTCH3	Q9UM47-1.2	R163F	Neutral	0.481
NOTCH3	Q9UM47-1.2	R163G	Neutral	0.126
NOTCH3	Q9UM47-1.2	R163H	Neutral	0.009
NOTCH3	Q9UM47-1.2	R163I	Neutral	0.471
NOTCH3	Q9UM47-1.2	R163K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R163L	Neutral	0.163
NOTCH3	Q9UM47-1.2	R163M	Neutral	0.041
NOTCH3	Q9UM47-1.2	R163N	Neutral	0.008
NOTCH3	Q9UM47-1.2	R163P	Neutral	0.145
NOTCH3	Q9UM47-1.2	R163Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	R163S	Neutral	0.034
NOTCH3	Q9UM47-1.2	R163T	Neutral	0.036
NOTCH3	Q9UM47-1.2	R163V	Neutral	0.451
NOTCH3	Q9UM47-1.2	R163W	Neutral	0.48
NOTCH3	Q9UM47-1.2	R163Y	Neutral	0.172
NOTCH3	Q9UM47-1.2	V164A	Neutral	0.003
NOTCH3	Q9UM47-1.2	V164C	Neutral	0.014
NOTCH3	Q9UM47-1.2	V164D	Neutral	0.229
NOTCH3	Q9UM47-1.2	V164E	Neutral	0.063
NOTCH3	Q9UM47-1.2	V164F	Neutral	0.013
NOTCH3	Q9UM47-1.2	V164G	Neutral	0.2
NOTCH3	Q9UM47-1.2	V164H	Neutral	0.229
NOTCH3	Q9UM47-1.2	V164I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V164K	Neutral	0.058
NOTCH3	Q9UM47-1.2	V164L	Neutral	0.001
NOTCH3	Q9UM47-1.2	V164M	Neutral	0.001
NOTCH3	Q9UM47-1.2	V164N	Neutral	0.232
NOTCH3	Q9UM47-1.2	V164P	Neutral	0.06
NOTCH3	Q9UM47-1.2	V164Q	Neutral	0.062
NOTCH3	Q9UM47-1.2	V164R	Neutral	0.21
NOTCH3	Q9UM47-1.2	V164S	Neutral	0.057
NOTCH3	Q9UM47-1.2	V164T	Neutral	0.003
NOTCH3	Q9UM47-1.2	V164W	Neutral	0.199
NOTCH3	Q9UM47-1.2	V164Y	Neutral	0.013
NOTCH3	Q9UM47-1.2	G165A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G165C	Neutral	0.119
NOTCH3	Q9UM47-1.2	G165D	Neutral	0.006
NOTCH3	Q9UM47-1.2	G165E	Neutral	0.026
NOTCH3	Q9UM47-1.2	G165F	Neutral	0.101
NOTCH3	Q9UM47-1.2	G165H	Neutral	0.025
NOTCH3	Q9UM47-1.2	G165I	Neutral	0.349
NOTCH3	Q9UM47-1.2	G165K	Neutral	0.024
NOTCH3	Q9UM47-1.2	G165L	Neutral	0.349
NOTCH3	Q9UM47-1.2	G165M	Neutral	0.105
NOTCH3	Q9UM47-1.2	G165N	Neutral	0.001
NOTCH3	Q9UM47-1.2	G165P	Neutral	0.028
NOTCH3	Q9UM47-1.2	G165Q	Neutral	0.026
NOTCH3	Q9UM47-1.2	G165R	Neutral	0.023
NOTCH3	Q9UM47-1.2	G165S	Neutral	0.001
NOTCH3	Q9UM47-1.2	G165T	Neutral	0.028
NOTCH3	Q9UM47-1.2	G165V	Neutral	0.112
NOTCH3	Q9UM47-1.2	G165W	Neutral	0.022
NOTCH3	Q9UM47-1.2	G165Y	Neutral	0.099
NOTCH3	Q9UM47-1.2	E166A	Neutral	0.001
NOTCH3	Q9UM47-1.2	E166C	Neutral	0.115
NOTCH3	Q9UM47-1.2	E166D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E166F	Neutral	0.028
NOTCH3	Q9UM47-1.2	E166G	Neutral	0.005
NOTCH3	Q9UM47-1.2	E166H	Neutral	0.0
NOTCH3	Q9UM47-1.2	E166I	Neutral	0.029
NOTCH3	Q9UM47-1.2	E166K	Neutral	0.0
NOTCH3	Q9UM47-1.2	E166L	Neutral	0.029
NOTCH3	Q9UM47-1.2	E166M	Neutral	0.006
NOTCH3	Q9UM47-1.2	E166N	Neutral	0.0
NOTCH3	Q9UM47-1.2	E166P	Neutral	0.001
NOTCH3	Q9UM47-1.2	E166Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E166R	Neutral	0.0
NOTCH3	Q9UM47-1.2	E166S	Neutral	0.0
NOTCH3	Q9UM47-1.2	E166T	Neutral	0.001
NOTCH3	Q9UM47-1.2	E166V	Neutral	0.007
NOTCH3	Q9UM47-1.2	E166W	Neutral	0.025
NOTCH3	Q9UM47-1.2	E166Y	Neutral	0.006
NOTCH3	Q9UM47-1.2	P167A	Neutral	0.042
NOTCH3	Q9UM47-1.2	P167C	Neutral	0.492
NOTCH3	Q9UM47-1.2	P167D	Neutral	0.046
NOTCH3	Q9UM47-1.2	P167E	Neutral	0.043
NOTCH3	Q9UM47-1.2	P167F	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	P167G	Neutral	0.156
NOTCH3	Q9UM47-1.2	P167H	Neutral	0.163
NOTCH3	Q9UM47-1.2	P167I	Neutral	0.465
NOTCH3	Q9UM47-1.2	P167K	Neutral	0.039
NOTCH3	Q9UM47-1.2	P167L	Neutral	0.465
NOTCH3	Q9UM47-1.2	P167M	Neutral	0.16
NOTCH3	Q9UM47-1.2	P167N	Neutral	0.176
NOTCH3	Q9UM47-1.2	P167Q	Neutral	0.042
NOTCH3	Q9UM47-1.2	P167R	Neutral	0.149
NOTCH3	Q9UM47-1.2	P167S	Neutral	0.043
NOTCH3	Q9UM47-1.2	P167T	Neutral	0.045
NOTCH3	Q9UM47-1.2	P167V	Neutral	0.17
NOTCH3	Q9UM47-1.2	P167W	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	P167Y	Neutral	0.447
NOTCH3	Q9UM47-1.2	C168A	Neutral	0.417
NOTCH3	Q9UM47-1.2	C168D	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C168E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C168F	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	C168G	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	C168H	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C168I	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	C168K	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	C168L	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	C168M	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	C168N	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C168P	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C168Q	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C168R	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	C168S	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	C168T	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	C168V	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	C168W	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	C168Y	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	R169A	Neutral	0.091
NOTCH3	Q9UM47-1.2	R169C	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	R169D	Neutral	0.331
NOTCH3	Q9UM47-1.2	R169E	Neutral	0.025
NOTCH3	Q9UM47-1.2	R169F	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	R169G	Neutral	0.296
NOTCH3	Q9UM47-1.2	R169H	Neutral	0.026
NOTCH3	Q9UM47-1.2	R169I	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	R169K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R169L	Neutral	0.364
NOTCH3	Q9UM47-1.2	R169M	Neutral	0.111
NOTCH3	Q9UM47-1.2	R169N	Neutral	0.024
NOTCH3	Q9UM47-1.2	R169P	Neutral	0.333
NOTCH3	Q9UM47-1.2	R169Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	R169S	Neutral	0.092
NOTCH3	Q9UM47-1.2	R169T	Neutral	0.099
NOTCH3	Q9UM47-1.2	R169V	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	R169W	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	R169Y	Neutral	0.378
NOTCH3	Q9UM47-1.2	H170A	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	H170C	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	H170D	Pathogenic	0.569
NOTCH3	Q9UM47-1.2	H170E	Neutral	0.237
NOTCH3	Q9UM47-1.2	H170F	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	H170G	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	H170I	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	H170K	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	H170L	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	H170M	Pathogenic	0.867
NOTCH3	Q9UM47-1.2	H170N	Neutral	0.061
NOTCH3	Q9UM47-1.2	H170P	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	H170Q	Neutral	0.24
NOTCH3	Q9UM47-1.2	H170R	Neutral	0.223
NOTCH3	Q9UM47-1.2	H170S	Pathogenic	0.55
NOTCH3	Q9UM47-1.2	H170T	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	H170V	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	H170W	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	H170Y	Neutral	0.014
NOTCH3	Q9UM47-1.2	G171A	Neutral	0.072
NOTCH3	Q9UM47-1.2	G171C	Pathogenic	0.873
NOTCH3	Q9UM47-1.2	G171D	Neutral	0.245
NOTCH3	Q9UM47-1.2	G171E	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	G171F	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	G171H	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	G171I	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	G171K	Pathogenic	0.556
NOTCH3	Q9UM47-1.2	G171L	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	G171M	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	G171N	Neutral	0.065
NOTCH3	Q9UM47-1.2	G171P	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	G171Q	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	G171R	Pathogenic	0.543
NOTCH3	Q9UM47-1.2	G171S	Neutral	0.071
NOTCH3	Q9UM47-1.2	G171T	Pathogenic	0.594
NOTCH3	Q9UM47-1.2	G171V	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	G171W	Pathogenic	0.531
NOTCH3	Q9UM47-1.2	G171Y	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G172A	Neutral	0.171
NOTCH3	Q9UM47-1.2	G172C	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	G172D	Neutral	0.462
NOTCH3	Q9UM47-1.2	G172E	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	G172F	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	G172H	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	G172I	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	G172K	Pathogenic	0.767
NOTCH3	Q9UM47-1.2	G172L	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	G172M	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	G172N	Neutral	0.156
NOTCH3	Q9UM47-1.2	G172P	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	G172Q	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	G172R	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	G172S	Neutral	0.167
NOTCH3	Q9UM47-1.2	G172T	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	G172V	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	G172W	Pathogenic	0.75
NOTCH3	Q9UM47-1.2	G172Y	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	T173A	Neutral	0.058
NOTCH3	Q9UM47-1.2	T173C	Neutral	0.233
NOTCH3	Q9UM47-1.2	T173D	Neutral	0.237
NOTCH3	Q9UM47-1.2	T173E	Neutral	0.227
NOTCH3	Q9UM47-1.2	T173F	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	T173G	Pathogenic	0.543
NOTCH3	Q9UM47-1.2	T173H	Pathogenic	0.562
NOTCH3	Q9UM47-1.2	T173I	Neutral	0.218
NOTCH3	Q9UM47-1.2	T173K	Neutral	0.21
NOTCH3	Q9UM47-1.2	T173L	Neutral	0.218
NOTCH3	Q9UM47-1.2	T173M	Neutral	0.217
NOTCH3	Q9UM47-1.2	T173N	Neutral	0.063
NOTCH3	Q9UM47-1.2	T173P	Neutral	0.235
NOTCH3	Q9UM47-1.2	T173Q	Neutral	0.223
NOTCH3	Q9UM47-1.2	T173R	Neutral	0.202
NOTCH3	Q9UM47-1.2	T173S	Neutral	0.014
NOTCH3	Q9UM47-1.2	T173V	Neutral	0.061
NOTCH3	Q9UM47-1.2	T173W	Pathogenic	0.523
NOTCH3	Q9UM47-1.2	T173Y	Pathogenic	0.541
NOTCH3	Q9UM47-1.2	C174A	Neutral	0.426
NOTCH3	Q9UM47-1.2	C174D	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C174E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C174F	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	C174G	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C174H	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C174I	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	C174K	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	C174L	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	C174M	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	C174N	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C174P	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C174Q	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C174R	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	C174S	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	C174T	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	C174V	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	C174W	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	C174Y	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	L175A	Neutral	0.044
NOTCH3	Q9UM47-1.2	L175C	Neutral	0.047
NOTCH3	Q9UM47-1.2	L175D	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	L175E	Pathogenic	0.532
NOTCH3	Q9UM47-1.2	L175F	Neutral	0.012
NOTCH3	Q9UM47-1.2	L175G	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	L175H	Pathogenic	0.539
NOTCH3	Q9UM47-1.2	L175I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L175K	Neutral	0.203
NOTCH3	Q9UM47-1.2	L175M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L175N	Pathogenic	0.519
NOTCH3	Q9UM47-1.2	L175P	Pathogenic	0.511
NOTCH3	Q9UM47-1.2	L175Q	Neutral	0.202
NOTCH3	Q9UM47-1.2	L175R	Neutral	0.195
NOTCH3	Q9UM47-1.2	L175S	Neutral	0.178
NOTCH3	Q9UM47-1.2	L175T	Neutral	0.049
NOTCH3	Q9UM47-1.2	L175V	Neutral	0.003
NOTCH3	Q9UM47-1.2	L175W	Neutral	0.183
NOTCH3	Q9UM47-1.2	L175Y	Neutral	0.051
NOTCH3	Q9UM47-1.2	N176A	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	N176C	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	N176D	Neutral	0.106
NOTCH3	Q9UM47-1.2	N176E	Neutral	0.344
NOTCH3	Q9UM47-1.2	N176F	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	N176G	Neutral	0.316
NOTCH3	Q9UM47-1.2	N176H	Neutral	0.101
NOTCH3	Q9UM47-1.2	N176I	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	N176K	Neutral	0.323
NOTCH3	Q9UM47-1.2	N176L	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	N176M	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	N176P	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	N176Q	Neutral	0.341
NOTCH3	Q9UM47-1.2	N176R	Neutral	0.312
NOTCH3	Q9UM47-1.2	N176S	Neutral	0.1
NOTCH3	Q9UM47-1.2	N176T	Neutral	0.355
NOTCH3	Q9UM47-1.2	N176V	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	N176W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	N176Y	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	T177A	Neutral	0.018
NOTCH3	Q9UM47-1.2	T177C	Neutral	0.084
NOTCH3	Q9UM47-1.2	T177D	Neutral	0.086
NOTCH3	Q9UM47-1.2	T177E	Neutral	0.082
NOTCH3	Q9UM47-1.2	T177F	Neutral	0.269
NOTCH3	Q9UM47-1.2	T177G	Neutral	0.265
NOTCH3	Q9UM47-1.2	T177H	Neutral	0.28
NOTCH3	Q9UM47-1.2	T177I	Neutral	0.078
NOTCH3	Q9UM47-1.2	T177K	Neutral	0.075
NOTCH3	Q9UM47-1.2	T177L	Neutral	0.078
NOTCH3	Q9UM47-1.2	T177M	Neutral	0.078
NOTCH3	Q9UM47-1.2	T177N	Neutral	0.02
NOTCH3	Q9UM47-1.2	T177P	Neutral	0.085
NOTCH3	Q9UM47-1.2	T177Q	Neutral	0.08
NOTCH3	Q9UM47-1.2	T177R	Neutral	0.071
NOTCH3	Q9UM47-1.2	T177S	Neutral	0.004
NOTCH3	Q9UM47-1.2	T177V	Neutral	0.019
NOTCH3	Q9UM47-1.2	T177W	Neutral	0.249
NOTCH3	Q9UM47-1.2	T177Y	Neutral	0.264
NOTCH3	Q9UM47-1.2	P178A	Neutral	0.085
NOTCH3	Q9UM47-1.2	P178C	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	P178D	Neutral	0.093
NOTCH3	Q9UM47-1.2	P178E	Neutral	0.087
NOTCH3	Q9UM47-1.2	P178F	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	P178G	Neutral	0.283
NOTCH3	Q9UM47-1.2	P178H	Neutral	0.294
NOTCH3	Q9UM47-1.2	P178I	Pathogenic	0.65
NOTCH3	Q9UM47-1.2	P178K	Neutral	0.079
NOTCH3	Q9UM47-1.2	P178L	Pathogenic	0.65
NOTCH3	Q9UM47-1.2	P178M	Neutral	0.289
NOTCH3	Q9UM47-1.2	P178N	Neutral	0.313
NOTCH3	Q9UM47-1.2	P178Q	Neutral	0.085
NOTCH3	Q9UM47-1.2	P178R	Neutral	0.272
NOTCH3	Q9UM47-1.2	P178S	Neutral	0.087
NOTCH3	Q9UM47-1.2	P178T	Neutral	0.091
NOTCH3	Q9UM47-1.2	P178V	Neutral	0.304
NOTCH3	Q9UM47-1.2	P178W	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	P178Y	Pathogenic	0.633
NOTCH3	Q9UM47-1.2	G179A	Neutral	0.185
NOTCH3	Q9UM47-1.2	G179C	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	G179D	Neutral	0.487
NOTCH3	Q9UM47-1.2	G179E	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	G179F	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	G179H	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	G179I	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	G179K	Pathogenic	0.785
NOTCH3	Q9UM47-1.2	G179L	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	G179M	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	G179N	Neutral	0.169
NOTCH3	Q9UM47-1.2	G179P	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	G179Q	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	G179R	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	G179S	Neutral	0.182
NOTCH3	Q9UM47-1.2	G179T	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	G179V	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	G179W	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	G179Y	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	S180A	Neutral	0.05
NOTCH3	Q9UM47-1.2	S180C	Pathogenic	0.515
NOTCH3	Q9UM47-1.2	S180D	Neutral	0.186
NOTCH3	Q9UM47-1.2	S180E	Neutral	0.175
NOTCH3	Q9UM47-1.2	S180F	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	S180G	Neutral	0.181
NOTCH3	Q9UM47-1.2	S180H	Neutral	0.482
NOTCH3	Q9UM47-1.2	S180I	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	S180K	Neutral	0.162
NOTCH3	Q9UM47-1.2	S180L	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	S180M	Neutral	0.479
NOTCH3	Q9UM47-1.2	S180N	Neutral	0.047
NOTCH3	Q9UM47-1.2	S180P	Pathogenic	0.51
NOTCH3	Q9UM47-1.2	S180Q	Neutral	0.172
NOTCH3	Q9UM47-1.2	S180R	Neutral	0.455
NOTCH3	Q9UM47-1.2	S180T	Neutral	0.047
NOTCH3	Q9UM47-1.2	S180V	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	S180W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	S180Y	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	F181A	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	F181C	Pathogenic	0.702
NOTCH3	Q9UM47-1.2	F181D	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	F181E	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	F181G	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	F181H	Neutral	0.371
NOTCH3	Q9UM47-1.2	F181I	Neutral	0.116
NOTCH3	Q9UM47-1.2	F181K	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	F181L	Neutral	0.116
NOTCH3	Q9UM47-1.2	F181M	Neutral	0.116
NOTCH3	Q9UM47-1.2	F181N	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	F181P	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	F181Q	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	F181R	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	F181S	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	F181T	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	F181V	Neutral	0.358
NOTCH3	Q9UM47-1.2	F181W	Neutral	0.026
NOTCH3	Q9UM47-1.2	F181Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	R182A	Neutral	0.241
NOTCH3	Q9UM47-1.2	R182C	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	R182D	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	R182E	Neutral	0.075
NOTCH3	Q9UM47-1.2	R182F	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	R182G	Pathogenic	0.572
NOTCH3	Q9UM47-1.2	R182H	Neutral	0.078
NOTCH3	Q9UM47-1.2	R182I	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	R182K	Neutral	0.004
NOTCH3	Q9UM47-1.2	R182L	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	R182M	Neutral	0.285
NOTCH3	Q9UM47-1.2	R182N	Neutral	0.072
NOTCH3	Q9UM47-1.2	R182P	Pathogenic	0.613
NOTCH3	Q9UM47-1.2	R182Q	Neutral	0.018
NOTCH3	Q9UM47-1.2	R182S	Neutral	0.244
NOTCH3	Q9UM47-1.2	R182T	Neutral	0.259
NOTCH3	Q9UM47-1.2	R182V	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	R182W	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	R182Y	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	C183A	Neutral	0.439
NOTCH3	Q9UM47-1.2	C183D	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C183E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C183F	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	C183G	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C183H	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C183I	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	C183K	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C183L	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	C183M	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	C183N	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C183P	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C183Q	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C183R	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	C183S	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	C183T	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	C183V	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	C183W	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	C183Y	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	Q184A	Neutral	0.115
NOTCH3	Q9UM47-1.2	Q184C	Pathogenic	0.744
NOTCH3	Q9UM47-1.2	Q184D	Neutral	0.03
NOTCH3	Q9UM47-1.2	Q184E	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q184F	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	Q184G	Neutral	0.354
NOTCH3	Q9UM47-1.2	Q184H	Neutral	0.033
NOTCH3	Q9UM47-1.2	Q184I	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	Q184K	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q184L	Neutral	0.408
NOTCH3	Q9UM47-1.2	Q184M	Neutral	0.032
NOTCH3	Q9UM47-1.2	Q184N	Neutral	0.031
NOTCH3	Q9UM47-1.2	Q184P	Neutral	0.125
NOTCH3	Q9UM47-1.2	Q184R	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q184S	Neutral	0.028
NOTCH3	Q9UM47-1.2	Q184T	Neutral	0.125
NOTCH3	Q9UM47-1.2	Q184V	Neutral	0.408
NOTCH3	Q9UM47-1.2	Q184W	Neutral	0.373
NOTCH3	Q9UM47-1.2	Q184Y	Neutral	0.124
NOTCH3	Q9UM47-1.2	C185A	Neutral	0.44
NOTCH3	Q9UM47-1.2	C185D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C185E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C185F	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	C185G	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C185H	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C185I	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	C185K	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C185L	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	C185M	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	C185N	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C185P	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C185Q	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C185R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C185S	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	C185T	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C185V	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	C185W	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	C185Y	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	P186A	Neutral	0.066
NOTCH3	Q9UM47-1.2	P186C	Pathogenic	0.612
NOTCH3	Q9UM47-1.2	P186D	Neutral	0.072
NOTCH3	Q9UM47-1.2	P186E	Neutral	0.068
NOTCH3	Q9UM47-1.2	P186F	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	P186G	Neutral	0.231
NOTCH3	Q9UM47-1.2	P186H	Neutral	0.24
NOTCH3	Q9UM47-1.2	P186I	Pathogenic	0.586
NOTCH3	Q9UM47-1.2	P186K	Neutral	0.062
NOTCH3	Q9UM47-1.2	P186L	Pathogenic	0.585
NOTCH3	Q9UM47-1.2	P186M	Neutral	0.236
NOTCH3	Q9UM47-1.2	P186N	Neutral	0.257
NOTCH3	Q9UM47-1.2	P186Q	Neutral	0.066
NOTCH3	Q9UM47-1.2	P186R	Neutral	0.222
NOTCH3	Q9UM47-1.2	P186S	Neutral	0.068
NOTCH3	Q9UM47-1.2	P186T	Neutral	0.071
NOTCH3	Q9UM47-1.2	P186V	Neutral	0.25
NOTCH3	Q9UM47-1.2	P186W	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	P186Y	Pathogenic	0.568
NOTCH3	Q9UM47-1.2	A187C	Neutral	0.008
NOTCH3	Q9UM47-1.2	A187D	Neutral	0.142
NOTCH3	Q9UM47-1.2	A187E	Neutral	0.033
NOTCH3	Q9UM47-1.2	A187F	Neutral	0.123
NOTCH3	Q9UM47-1.2	A187G	Neutral	0.008
NOTCH3	Q9UM47-1.2	A187H	Neutral	0.129
NOTCH3	Q9UM47-1.2	A187I	Neutral	0.031
NOTCH3	Q9UM47-1.2	A187K	Neutral	0.03
NOTCH3	Q9UM47-1.2	A187L	Neutral	0.031
NOTCH3	Q9UM47-1.2	A187M	Neutral	0.031
NOTCH3	Q9UM47-1.2	A187N	Neutral	0.14
NOTCH3	Q9UM47-1.2	A187P	Neutral	0.035
NOTCH3	Q9UM47-1.2	A187Q	Neutral	0.032
NOTCH3	Q9UM47-1.2	A187R	Neutral	0.028
NOTCH3	Q9UM47-1.2	A187S	Neutral	0.002
NOTCH3	Q9UM47-1.2	A187T	Neutral	0.008
NOTCH3	Q9UM47-1.2	A187V	Neutral	0.008
NOTCH3	Q9UM47-1.2	A187W	Neutral	0.366
NOTCH3	Q9UM47-1.2	A187Y	Neutral	0.12
NOTCH3	Q9UM47-1.2	G188A	Neutral	0.03
NOTCH3	Q9UM47-1.2	G188C	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	G188D	Neutral	0.114
NOTCH3	Q9UM47-1.2	G188E	Neutral	0.352
NOTCH3	Q9UM47-1.2	G188F	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	G188H	Neutral	0.343
NOTCH3	Q9UM47-1.2	G188I	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	G188K	Neutral	0.33
NOTCH3	Q9UM47-1.2	G188L	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	G188M	Pathogenic	0.701
NOTCH3	Q9UM47-1.2	G188N	Neutral	0.027
NOTCH3	Q9UM47-1.2	G188P	Neutral	0.369
NOTCH3	Q9UM47-1.2	G188Q	Neutral	0.347
NOTCH3	Q9UM47-1.2	G188R	Neutral	0.319
NOTCH3	Q9UM47-1.2	G188S	Neutral	0.029
NOTCH3	Q9UM47-1.2	G188T	Neutral	0.366
NOTCH3	Q9UM47-1.2	G188V	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	G188W	Neutral	0.309
NOTCH3	Q9UM47-1.2	G188Y	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	Y189A	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	Y189C	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	Y189D	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	Y189E	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	Y189F	Neutral	0.003
NOTCH3	Q9UM47-1.2	Y189G	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	Y189H	Neutral	0.014
NOTCH3	Q9UM47-1.2	Y189I	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	Y189K	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	Y189L	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	Y189M	Pathogenic	0.572
NOTCH3	Q9UM47-1.2	Y189N	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	Y189P	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	Y189Q	Pathogenic	0.564
NOTCH3	Q9UM47-1.2	Y189R	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	Y189S	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	Y189T	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	Y189V	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	Y189W	Neutral	0.014
NOTCH3	Q9UM47-1.2	T190A	Neutral	0.242
NOTCH3	Q9UM47-1.2	T190C	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	T190D	Pathogenic	0.616
NOTCH3	Q9UM47-1.2	T190E	Pathogenic	0.603
NOTCH3	Q9UM47-1.2	T190F	Pathogenic	0.863
NOTCH3	Q9UM47-1.2	T190G	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	T190H	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	T190I	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	T190K	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	T190L	Pathogenic	0.59
NOTCH3	Q9UM47-1.2	T190M	Pathogenic	0.589
NOTCH3	Q9UM47-1.2	T190N	Neutral	0.26
NOTCH3	Q9UM47-1.2	T190P	Pathogenic	0.614
NOTCH3	Q9UM47-1.2	T190Q	Pathogenic	0.598
NOTCH3	Q9UM47-1.2	T190R	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	T190S	Neutral	0.067
NOTCH3	Q9UM47-1.2	T190V	Neutral	0.253
NOTCH3	Q9UM47-1.2	T190W	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	T190Y	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	G191A	Neutral	0.207
NOTCH3	Q9UM47-1.2	G191C	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G191D	Pathogenic	0.521
NOTCH3	Q9UM47-1.2	G191E	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	G191F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	G191H	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	G191I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G191K	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	G191L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G191M	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	G191N	Neutral	0.19
NOTCH3	Q9UM47-1.2	G191P	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	G191Q	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	G191R	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	G191S	Neutral	0.203
NOTCH3	Q9UM47-1.2	G191T	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	G191V	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G191W	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	G191Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	P192A	Neutral	0.026
NOTCH3	Q9UM47-1.2	P192C	Neutral	0.374
NOTCH3	Q9UM47-1.2	P192D	Neutral	0.029
NOTCH3	Q9UM47-1.2	P192E	Neutral	0.027
NOTCH3	Q9UM47-1.2	P192F	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	P192G	Neutral	0.102
NOTCH3	Q9UM47-1.2	P192H	Neutral	0.107
NOTCH3	Q9UM47-1.2	P192I	Neutral	0.348
NOTCH3	Q9UM47-1.2	P192K	Neutral	0.024
NOTCH3	Q9UM47-1.2	P192L	Neutral	0.348
NOTCH3	Q9UM47-1.2	P192M	Neutral	0.105
NOTCH3	Q9UM47-1.2	P192N	Neutral	0.116
NOTCH3	Q9UM47-1.2	P192Q	Neutral	0.026
NOTCH3	Q9UM47-1.2	P192R	Neutral	0.097
NOTCH3	Q9UM47-1.2	P192S	Neutral	0.027
NOTCH3	Q9UM47-1.2	P192T	Neutral	0.028
NOTCH3	Q9UM47-1.2	P192V	Neutral	0.112
NOTCH3	Q9UM47-1.2	P192W	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	P192Y	Neutral	0.332
NOTCH3	Q9UM47-1.2	L193A	Neutral	0.015
NOTCH3	Q9UM47-1.2	L193C	Neutral	0.016
NOTCH3	Q9UM47-1.2	L193D	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	L193E	Neutral	0.269
NOTCH3	Q9UM47-1.2	L193F	Neutral	0.004
NOTCH3	Q9UM47-1.2	L193G	Pathogenic	0.569
NOTCH3	Q9UM47-1.2	L193H	Neutral	0.275
NOTCH3	Q9UM47-1.2	L193I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L193K	Neutral	0.076
NOTCH3	Q9UM47-1.2	L193M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L193N	Neutral	0.26
NOTCH3	Q9UM47-1.2	L193P	Neutral	0.253
NOTCH3	Q9UM47-1.2	L193Q	Neutral	0.076
NOTCH3	Q9UM47-1.2	L193R	Neutral	0.073
NOTCH3	Q9UM47-1.2	L193S	Neutral	0.066
NOTCH3	Q9UM47-1.2	L193T	Neutral	0.016
NOTCH3	Q9UM47-1.2	L193V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L193W	Neutral	0.068
NOTCH3	Q9UM47-1.2	L193Y	Neutral	0.017
NOTCH3	Q9UM47-1.2	C194A	Neutral	0.451
NOTCH3	Q9UM47-1.2	C194D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C194E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C194F	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	C194G	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C194H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C194I	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	C194K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C194L	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	C194M	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	C194N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C194P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C194Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C194R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C194S	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	C194T	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	C194V	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	C194W	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	C194Y	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	E195A	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	E195C	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	E195D	Neutral	0.014
NOTCH3	Q9UM47-1.2	E195F	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	E195G	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	E195H	Neutral	0.236
NOTCH3	Q9UM47-1.2	E195I	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	E195K	Neutral	0.06
NOTCH3	Q9UM47-1.2	E195L	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	E195M	Pathogenic	0.863
NOTCH3	Q9UM47-1.2	E195N	Neutral	0.232
NOTCH3	Q9UM47-1.2	E195P	Pathogenic	0.576
NOTCH3	Q9UM47-1.2	E195Q	Neutral	0.015
NOTCH3	Q9UM47-1.2	E195R	Neutral	0.215
NOTCH3	Q9UM47-1.2	E195S	Neutral	0.217
NOTCH3	Q9UM47-1.2	E195T	Pathogenic	0.578
NOTCH3	Q9UM47-1.2	E195V	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	E195W	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	E195Y	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	N196A	Neutral	0.049
NOTCH3	Q9UM47-1.2	N196C	Neutral	0.203
NOTCH3	Q9UM47-1.2	N196D	Neutral	0.001
NOTCH3	Q9UM47-1.2	N196E	Neutral	0.003
NOTCH3	Q9UM47-1.2	N196F	Neutral	0.186
NOTCH3	Q9UM47-1.2	N196G	Neutral	0.002
NOTCH3	Q9UM47-1.2	N196H	Neutral	0.001
NOTCH3	Q9UM47-1.2	N196I	Neutral	0.193
NOTCH3	Q9UM47-1.2	N196K	Neutral	0.002
NOTCH3	Q9UM47-1.2	N196L	Neutral	0.193
NOTCH3	Q9UM47-1.2	N196M	Neutral	0.05
NOTCH3	Q9UM47-1.2	N196P	Neutral	0.054
NOTCH3	Q9UM47-1.2	N196Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	N196R	Neutral	0.002
NOTCH3	Q9UM47-1.2	N196S	Neutral	0.001
NOTCH3	Q9UM47-1.2	N196T	Neutral	0.003
NOTCH3	Q9UM47-1.2	N196V	Neutral	0.204
NOTCH3	Q9UM47-1.2	N196W	Neutral	0.484
NOTCH3	Q9UM47-1.2	N196Y	Neutral	0.047
NOTCH3	Q9UM47-1.2	P197A	Neutral	0.083
NOTCH3	Q9UM47-1.2	P197C	Pathogenic	0.668
NOTCH3	Q9UM47-1.2	P197D	Neutral	0.09
NOTCH3	Q9UM47-1.2	P197E	Neutral	0.085
NOTCH3	Q9UM47-1.2	P197F	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	P197G	Neutral	0.277
NOTCH3	Q9UM47-1.2	P197H	Neutral	0.288
NOTCH3	Q9UM47-1.2	P197I	Pathogenic	0.644
NOTCH3	Q9UM47-1.2	P197K	Neutral	0.078
NOTCH3	Q9UM47-1.2	P197L	Pathogenic	0.644
NOTCH3	Q9UM47-1.2	P197M	Neutral	0.283
NOTCH3	Q9UM47-1.2	P197N	Neutral	0.307
NOTCH3	Q9UM47-1.2	P197Q	Neutral	0.083
NOTCH3	Q9UM47-1.2	P197R	Neutral	0.267
NOTCH3	Q9UM47-1.2	P197S	Neutral	0.085
NOTCH3	Q9UM47-1.2	P197T	Neutral	0.089
NOTCH3	Q9UM47-1.2	P197V	Neutral	0.298
NOTCH3	Q9UM47-1.2	P197W	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	P197Y	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	A198C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A198D	Neutral	0.057
NOTCH3	Q9UM47-1.2	A198E	Neutral	0.012
NOTCH3	Q9UM47-1.2	A198F	Neutral	0.049
NOTCH3	Q9UM47-1.2	A198G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A198H	Neutral	0.052
NOTCH3	Q9UM47-1.2	A198I	Neutral	0.012
NOTCH3	Q9UM47-1.2	A198K	Neutral	0.011
NOTCH3	Q9UM47-1.2	A198L	Neutral	0.012
NOTCH3	Q9UM47-1.2	A198M	Neutral	0.012
NOTCH3	Q9UM47-1.2	A198N	Neutral	0.056
NOTCH3	Q9UM47-1.2	A198P	Neutral	0.013
NOTCH3	Q9UM47-1.2	A198Q	Neutral	0.012
NOTCH3	Q9UM47-1.2	A198R	Neutral	0.011
NOTCH3	Q9UM47-1.2	A198S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A198T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A198V	Neutral	0.003
NOTCH3	Q9UM47-1.2	A198W	Neutral	0.175
NOTCH3	Q9UM47-1.2	A198Y	Neutral	0.048
NOTCH3	Q9UM47-1.2	V199A	Neutral	0.094
NOTCH3	Q9UM47-1.2	V199C	Neutral	0.336
NOTCH3	Q9UM47-1.2	V199D	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	V199E	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	V199F	Neutral	0.327
NOTCH3	Q9UM47-1.2	V199G	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	V199H	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	V199I	Neutral	0.001
NOTCH3	Q9UM47-1.2	V199K	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	V199L	Neutral	0.024
NOTCH3	Q9UM47-1.2	V199M	Neutral	0.024
NOTCH3	Q9UM47-1.2	V199N	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	V199P	Pathogenic	0.701
NOTCH3	Q9UM47-1.2	V199Q	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	V199R	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	V199S	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	V199T	Neutral	0.103
NOTCH3	Q9UM47-1.2	V199W	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	V199Y	Neutral	0.322
NOTCH3	Q9UM47-1.2	P200A	Pathogenic	0.64
NOTCH3	Q9UM47-1.2	P200C	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	P200D	Pathogenic	0.662
NOTCH3	Q9UM47-1.2	P200E	Pathogenic	0.646
NOTCH3	Q9UM47-1.2	P200F	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P200G	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	P200H	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	P200I	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	P200K	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	P200L	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	P200M	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	P200N	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	P200Q	Pathogenic	0.641
NOTCH3	Q9UM47-1.2	P200R	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	P200S	Pathogenic	0.646
NOTCH3	Q9UM47-1.2	P200T	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	P200V	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	P200W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	P200Y	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	C201A	Neutral	0.445
NOTCH3	Q9UM47-1.2	C201D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C201E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C201F	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C201G	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C201H	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C201I	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	C201K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C201L	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	C201M	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	C201N	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C201P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C201Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C201R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C201S	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	C201T	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	C201V	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	C201W	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	C201Y	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	A202C	Neutral	0.029
NOTCH3	Q9UM47-1.2	A202D	Neutral	0.381
NOTCH3	Q9UM47-1.2	A202E	Neutral	0.112
NOTCH3	Q9UM47-1.2	A202F	Neutral	0.343
NOTCH3	Q9UM47-1.2	A202G	Neutral	0.029
NOTCH3	Q9UM47-1.2	A202H	Neutral	0.355
NOTCH3	Q9UM47-1.2	A202I	Neutral	0.107
NOTCH3	Q9UM47-1.2	A202K	Neutral	0.103
NOTCH3	Q9UM47-1.2	A202L	Neutral	0.107
NOTCH3	Q9UM47-1.2	A202M	Neutral	0.106
NOTCH3	Q9UM47-1.2	A202N	Neutral	0.376
NOTCH3	Q9UM47-1.2	A202P	Neutral	0.119
NOTCH3	Q9UM47-1.2	A202Q	Neutral	0.11
NOTCH3	Q9UM47-1.2	A202R	Neutral	0.098
NOTCH3	Q9UM47-1.2	A202S	Neutral	0.007
NOTCH3	Q9UM47-1.2	A202T	Neutral	0.028
NOTCH3	Q9UM47-1.2	A202V	Neutral	0.027
NOTCH3	Q9UM47-1.2	A202W	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	A202Y	Neutral	0.336
NOTCH3	Q9UM47-1.2	P203A	Pathogenic	0.656
NOTCH3	Q9UM47-1.2	P203C	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	P203D	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	P203E	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	P203F	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P203G	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	P203H	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	P203I	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	P203K	Pathogenic	0.639
NOTCH3	Q9UM47-1.2	P203L	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	P203M	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	P203N	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	P203Q	Pathogenic	0.656
NOTCH3	Q9UM47-1.2	P203R	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	P203S	Pathogenic	0.662
NOTCH3	Q9UM47-1.2	P203T	Pathogenic	0.673
NOTCH3	Q9UM47-1.2	P203V	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	P203W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	P203Y	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	S204A	Neutral	0.086
NOTCH3	Q9UM47-1.2	S204C	Pathogenic	0.656
NOTCH3	Q9UM47-1.2	S204D	Neutral	0.291
NOTCH3	Q9UM47-1.2	S204E	Neutral	0.277
NOTCH3	Q9UM47-1.2	S204F	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	S204G	Neutral	0.284
NOTCH3	Q9UM47-1.2	S204H	Pathogenic	0.626
NOTCH3	Q9UM47-1.2	S204I	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	S204K	Neutral	0.258
NOTCH3	Q9UM47-1.2	S204L	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	S204M	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	S204N	Neutral	0.081
NOTCH3	Q9UM47-1.2	S204P	Pathogenic	0.652
NOTCH3	Q9UM47-1.2	S204Q	Neutral	0.272
NOTCH3	Q9UM47-1.2	S204R	Pathogenic	0.6
NOTCH3	Q9UM47-1.2	S204T	Neutral	0.082
NOTCH3	Q9UM47-1.2	S204V	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	S204W	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	S204Y	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	P205A	Pathogenic	0.521
NOTCH3	Q9UM47-1.2	P205C	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	P205D	Pathogenic	0.544
NOTCH3	Q9UM47-1.2	P205E	Pathogenic	0.526
NOTCH3	Q9UM47-1.2	P205F	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	P205G	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	P205H	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	P205I	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	P205K	Pathogenic	0.502
NOTCH3	Q9UM47-1.2	P205L	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	P205M	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	P205N	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	P205Q	Pathogenic	0.521
NOTCH3	Q9UM47-1.2	P205R	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	P205S	Pathogenic	0.527
NOTCH3	Q9UM47-1.2	P205T	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	P205V	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	P205W	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	P205Y	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	C206A	Neutral	0.445
NOTCH3	Q9UM47-1.2	C206D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C206E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C206F	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C206G	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C206H	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C206I	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	C206K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C206L	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	C206M	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	C206N	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C206P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C206Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C206R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C206S	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	C206T	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	C206V	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	C206W	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	C206Y	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	R207A	Neutral	0.024
NOTCH3	Q9UM47-1.2	R207C	Neutral	0.36
NOTCH3	Q9UM47-1.2	R207D	Neutral	0.11
NOTCH3	Q9UM47-1.2	R207E	Neutral	0.006
NOTCH3	Q9UM47-1.2	R207F	Neutral	0.406
NOTCH3	Q9UM47-1.2	R207G	Neutral	0.096
NOTCH3	Q9UM47-1.2	R207H	Neutral	0.007
NOTCH3	Q9UM47-1.2	R207I	Neutral	0.396
NOTCH3	Q9UM47-1.2	R207K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R207L	Neutral	0.126
NOTCH3	Q9UM47-1.2	R207M	Neutral	0.03
NOTCH3	Q9UM47-1.2	R207N	Neutral	0.006
NOTCH3	Q9UM47-1.2	R207P	Neutral	0.111
NOTCH3	Q9UM47-1.2	R207Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	R207S	Neutral	0.025
NOTCH3	Q9UM47-1.2	R207T	Neutral	0.027
NOTCH3	Q9UM47-1.2	R207V	Neutral	0.377
NOTCH3	Q9UM47-1.2	R207W	Neutral	0.405
NOTCH3	Q9UM47-1.2	R207Y	Neutral	0.132
NOTCH3	Q9UM47-1.2	N208A	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	N208C	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	N208D	Neutral	0.102
NOTCH3	Q9UM47-1.2	N208E	Neutral	0.334
NOTCH3	Q9UM47-1.2	N208F	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	N208G	Neutral	0.305
NOTCH3	Q9UM47-1.2	N208H	Neutral	0.097
NOTCH3	Q9UM47-1.2	N208I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	N208K	Neutral	0.312
NOTCH3	Q9UM47-1.2	N208L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	N208M	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	N208P	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	N208Q	Neutral	0.33
NOTCH3	Q9UM47-1.2	N208R	Neutral	0.302
NOTCH3	Q9UM47-1.2	N208S	Neutral	0.096
NOTCH3	Q9UM47-1.2	N208T	Neutral	0.344
NOTCH3	Q9UM47-1.2	N208V	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	N208W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	N208Y	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	G209A	Neutral	0.181
NOTCH3	Q9UM47-1.2	G209C	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	G209D	Neutral	0.48
NOTCH3	Q9UM47-1.2	G209E	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	G209F	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	G209H	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	G209I	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	G209K	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	G209L	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	G209M	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	G209N	Neutral	0.166
NOTCH3	Q9UM47-1.2	G209P	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	G209Q	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	G209R	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	G209S	Neutral	0.178
NOTCH3	Q9UM47-1.2	G209T	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	G209V	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	G209W	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	G209Y	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	G210A	Neutral	0.199
NOTCH3	Q9UM47-1.2	G210C	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G210D	Pathogenic	0.508
NOTCH3	Q9UM47-1.2	G210E	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	G210F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	G210H	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	G210I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G210K	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	G210L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G210M	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	G210N	Neutral	0.182
NOTCH3	Q9UM47-1.2	G210P	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	G210Q	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	G210R	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	G210S	Neutral	0.195
NOTCH3	Q9UM47-1.2	G210T	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	G210V	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	G210W	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	G210Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	T211A	Neutral	0.312
NOTCH3	Q9UM47-1.2	T211C	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	T211D	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	T211E	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	T211F	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	T211G	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	T211H	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	T211I	Pathogenic	0.672
NOTCH3	Q9UM47-1.2	T211K	Pathogenic	0.662
NOTCH3	Q9UM47-1.2	T211L	Pathogenic	0.672
NOTCH3	Q9UM47-1.2	T211M	Pathogenic	0.671
NOTCH3	Q9UM47-1.2	T211N	Neutral	0.333
NOTCH3	Q9UM47-1.2	T211P	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	T211Q	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	T211R	Pathogenic	0.651
NOTCH3	Q9UM47-1.2	T211S	Neutral	0.093
NOTCH3	Q9UM47-1.2	T211V	Neutral	0.325
NOTCH3	Q9UM47-1.2	T211W	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	T211Y	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	C212A	Neutral	0.444
NOTCH3	Q9UM47-1.2	C212D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C212E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C212F	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C212G	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C212H	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C212I	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	C212K	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C212L	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	C212M	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	C212N	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C212P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C212Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C212R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C212S	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	C212T	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	C212V	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	C212W	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	C212Y	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	R213A	Neutral	0.41
NOTCH3	Q9UM47-1.2	R213C	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	R213D	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	R213E	Neutral	0.151
NOTCH3	Q9UM47-1.2	R213F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	R213G	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	R213H	Neutral	0.156
NOTCH3	Q9UM47-1.2	R213I	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	R213K	Neutral	0.009
NOTCH3	Q9UM47-1.2	R213L	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	R213M	Neutral	0.465
NOTCH3	Q9UM47-1.2	R213N	Neutral	0.145
NOTCH3	Q9UM47-1.2	R213P	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	R213Q	Neutral	0.038
NOTCH3	Q9UM47-1.2	R213S	Neutral	0.414
NOTCH3	Q9UM47-1.2	R213T	Neutral	0.434
NOTCH3	Q9UM47-1.2	R213V	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	R213W	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	R213Y	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	Q214A	Pathogenic	0.511
NOTCH3	Q9UM47-1.2	Q214C	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	Q214D	Neutral	0.201
NOTCH3	Q9UM47-1.2	Q214E	Neutral	0.013
NOTCH3	Q9UM47-1.2	Q214F	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	Q214G	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	Q214H	Neutral	0.213
NOTCH3	Q9UM47-1.2	Q214I	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	Q214K	Neutral	0.053
NOTCH3	Q9UM47-1.2	Q214L	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	Q214M	Neutral	0.211
NOTCH3	Q9UM47-1.2	Q214N	Neutral	0.204
NOTCH3	Q9UM47-1.2	Q214P	Pathogenic	0.534
NOTCH3	Q9UM47-1.2	Q214R	Neutral	0.05
NOTCH3	Q9UM47-1.2	Q214S	Neutral	0.19
NOTCH3	Q9UM47-1.2	Q214T	Pathogenic	0.536
NOTCH3	Q9UM47-1.2	Q214V	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	Q214W	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	Q214Y	Pathogenic	0.532
NOTCH3	Q9UM47-1.2	S215A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S215C	Neutral	0.016
NOTCH3	Q9UM47-1.2	S215D	Neutral	0.004
NOTCH3	Q9UM47-1.2	S215E	Neutral	0.003
NOTCH3	Q9UM47-1.2	S215F	Neutral	0.06
NOTCH3	Q9UM47-1.2	S215G	Neutral	0.003
NOTCH3	Q9UM47-1.2	S215H	Neutral	0.014
NOTCH3	Q9UM47-1.2	S215I	Neutral	0.062
NOTCH3	Q9UM47-1.2	S215K	Neutral	0.003
NOTCH3	Q9UM47-1.2	S215L	Neutral	0.062
NOTCH3	Q9UM47-1.2	S215M	Neutral	0.014
NOTCH3	Q9UM47-1.2	S215N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S215P	Neutral	0.016
NOTCH3	Q9UM47-1.2	S215Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	S215R	Neutral	0.013
NOTCH3	Q9UM47-1.2	S215T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S215V	Neutral	0.066
NOTCH3	Q9UM47-1.2	S215W	Neutral	0.206
NOTCH3	Q9UM47-1.2	S215Y	Neutral	0.058
NOTCH3	Q9UM47-1.2	G216A	Neutral	0.045
NOTCH3	Q9UM47-1.2	G216C	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	G216D	Neutral	0.165
NOTCH3	Q9UM47-1.2	G216E	Neutral	0.456
NOTCH3	Q9UM47-1.2	G216F	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	G216H	Neutral	0.446
NOTCH3	Q9UM47-1.2	G216I	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	G216K	Neutral	0.432
NOTCH3	Q9UM47-1.2	G216L	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	G216M	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	G216N	Neutral	0.041
NOTCH3	Q9UM47-1.2	G216P	Neutral	0.474
NOTCH3	Q9UM47-1.2	G216Q	Neutral	0.45
NOTCH3	Q9UM47-1.2	G216R	Neutral	0.42
NOTCH3	Q9UM47-1.2	G216S	Neutral	0.044
NOTCH3	Q9UM47-1.2	G216T	Neutral	0.471
NOTCH3	Q9UM47-1.2	G216V	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	G216W	Neutral	0.408
NOTCH3	Q9UM47-1.2	G216Y	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	D217A	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	D217C	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	D217E	Neutral	0.006
NOTCH3	Q9UM47-1.2	D217F	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	D217G	Neutral	0.332
NOTCH3	Q9UM47-1.2	D217H	Neutral	0.346
NOTCH3	Q9UM47-1.2	D217I	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	D217K	Neutral	0.33
NOTCH3	Q9UM47-1.2	D217L	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	D217M	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	D217N	Neutral	0.027
NOTCH3	Q9UM47-1.2	D217P	Neutral	0.37
NOTCH3	Q9UM47-1.2	D217Q	Neutral	0.105
NOTCH3	Q9UM47-1.2	D217R	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	D217S	Neutral	0.107
NOTCH3	Q9UM47-1.2	D217T	Neutral	0.369
NOTCH3	Q9UM47-1.2	D217V	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	D217W	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	D217Y	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	L218A	Neutral	0.015
NOTCH3	Q9UM47-1.2	L218C	Neutral	0.017
NOTCH3	Q9UM47-1.2	L218D	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	L218E	Neutral	0.278
NOTCH3	Q9UM47-1.2	L218F	Neutral	0.004
NOTCH3	Q9UM47-1.2	L218G	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	L218H	Neutral	0.284
NOTCH3	Q9UM47-1.2	L218I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L218K	Neutral	0.079
NOTCH3	Q9UM47-1.2	L218M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L218N	Neutral	0.268
NOTCH3	Q9UM47-1.2	L218P	Neutral	0.262
NOTCH3	Q9UM47-1.2	L218Q	Neutral	0.079
NOTCH3	Q9UM47-1.2	L218R	Neutral	0.076
NOTCH3	Q9UM47-1.2	L218S	Neutral	0.068
NOTCH3	Q9UM47-1.2	L218T	Neutral	0.017
NOTCH3	Q9UM47-1.2	L218V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L218W	Neutral	0.071
NOTCH3	Q9UM47-1.2	L218Y	Neutral	0.018
NOTCH3	Q9UM47-1.2	T219A	Neutral	0.1
NOTCH3	Q9UM47-1.2	T219C	Neutral	0.354
NOTCH3	Q9UM47-1.2	T219D	Neutral	0.359
NOTCH3	Q9UM47-1.2	T219E	Neutral	0.346
NOTCH3	Q9UM47-1.2	T219F	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	T219G	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	T219H	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	T219I	Neutral	0.334
NOTCH3	Q9UM47-1.2	T219K	Neutral	0.325
NOTCH3	Q9UM47-1.2	T219L	Neutral	0.334
NOTCH3	Q9UM47-1.2	T219M	Neutral	0.333
NOTCH3	Q9UM47-1.2	T219N	Neutral	0.109
NOTCH3	Q9UM47-1.2	T219P	Neutral	0.357
NOTCH3	Q9UM47-1.2	T219Q	Neutral	0.341
NOTCH3	Q9UM47-1.2	T219R	Neutral	0.314
NOTCH3	Q9UM47-1.2	T219S	Neutral	0.024
NOTCH3	Q9UM47-1.2	T219V	Neutral	0.106
NOTCH3	Q9UM47-1.2	T219W	Pathogenic	0.664
NOTCH3	Q9UM47-1.2	T219Y	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	Y220A	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	Y220C	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	Y220D	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	Y220E	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	Y220F	Neutral	0.005
NOTCH3	Q9UM47-1.2	Y220G	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	Y220H	Neutral	0.02
NOTCH3	Q9UM47-1.2	Y220I	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	Y220K	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	Y220L	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	Y220M	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	Y220N	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	Y220P	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	Y220Q	Pathogenic	0.651
NOTCH3	Q9UM47-1.2	Y220R	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	Y220S	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	Y220T	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	Y220V	Pathogenic	0.641
NOTCH3	Q9UM47-1.2	Y220W	Neutral	0.02
NOTCH3	Q9UM47-1.2	D221A	Neutral	0.264
NOTCH3	Q9UM47-1.2	D221C	Pathogenic	0.639
NOTCH3	Q9UM47-1.2	D221E	Neutral	0.001
NOTCH3	Q9UM47-1.2	D221F	Pathogenic	0.605
NOTCH3	Q9UM47-1.2	D221G	Neutral	0.068
NOTCH3	Q9UM47-1.2	D221H	Neutral	0.072
NOTCH3	Q9UM47-1.2	D221I	Pathogenic	0.615
NOTCH3	Q9UM47-1.2	D221K	Neutral	0.068
NOTCH3	Q9UM47-1.2	D221L	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	D221M	Pathogenic	0.614
NOTCH3	Q9UM47-1.2	D221N	Neutral	0.004
NOTCH3	Q9UM47-1.2	D221P	Neutral	0.08
NOTCH3	Q9UM47-1.2	D221Q	Neutral	0.017
NOTCH3	Q9UM47-1.2	D221R	Neutral	0.239
NOTCH3	Q9UM47-1.2	D221S	Neutral	0.017
NOTCH3	Q9UM47-1.2	D221T	Neutral	0.079
NOTCH3	Q9UM47-1.2	D221V	Pathogenic	0.631
NOTCH3	Q9UM47-1.2	D221W	Pathogenic	0.863
NOTCH3	Q9UM47-1.2	D221Y	Pathogenic	0.598
NOTCH3	Q9UM47-1.2	C222A	Neutral	0.448
NOTCH3	Q9UM47-1.2	C222D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C222E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C222F	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C222G	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C222H	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C222I	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	C222K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C222L	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	C222M	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	C222N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C222P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C222Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C222R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C222S	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	C222T	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	C222V	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	C222W	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	C222Y	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	A223C	Neutral	0.014
NOTCH3	Q9UM47-1.2	A223D	Neutral	0.228
NOTCH3	Q9UM47-1.2	A223E	Neutral	0.057
NOTCH3	Q9UM47-1.2	A223F	Neutral	0.2
NOTCH3	Q9UM47-1.2	A223G	Neutral	0.014
NOTCH3	Q9UM47-1.2	A223H	Neutral	0.209
NOTCH3	Q9UM47-1.2	A223I	Neutral	0.054
NOTCH3	Q9UM47-1.2	A223K	Neutral	0.052
NOTCH3	Q9UM47-1.2	A223L	Neutral	0.054
NOTCH3	Q9UM47-1.2	A223M	Neutral	0.054
NOTCH3	Q9UM47-1.2	A223N	Neutral	0.225
NOTCH3	Q9UM47-1.2	A223P	Neutral	0.061
NOTCH3	Q9UM47-1.2	A223Q	Neutral	0.056
NOTCH3	Q9UM47-1.2	A223R	Neutral	0.05
NOTCH3	Q9UM47-1.2	A223S	Neutral	0.003
NOTCH3	Q9UM47-1.2	A223T	Neutral	0.014
NOTCH3	Q9UM47-1.2	A223V	Neutral	0.013
NOTCH3	Q9UM47-1.2	A223W	Pathogenic	0.507
NOTCH3	Q9UM47-1.2	A223Y	Neutral	0.195
NOTCH3	Q9UM47-1.2	C224A	Neutral	0.448
NOTCH3	Q9UM47-1.2	C224D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C224E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C224F	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C224G	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C224H	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C224I	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	C224K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C224L	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	C224M	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	C224N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C224P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C224Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C224R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C224S	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	C224T	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	C224V	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	C224W	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	C224Y	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	L225A	Neutral	0.467
NOTCH3	Q9UM47-1.2	L225C	Neutral	0.483
NOTCH3	Q9UM47-1.2	L225D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	L225E	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	L225F	Neutral	0.185
NOTCH3	Q9UM47-1.2	L225G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	L225H	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	L225I	Neutral	0.011
NOTCH3	Q9UM47-1.2	L225K	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	L225M	Neutral	0.011
NOTCH3	Q9UM47-1.2	L225N	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	L225P	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	L225Q	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	L225R	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	L225S	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	L225T	Neutral	0.492
NOTCH3	Q9UM47-1.2	L225V	Neutral	0.046
NOTCH3	Q9UM47-1.2	L225W	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	L225Y	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	P226A	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	P226C	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	P226D	Pathogenic	0.561
NOTCH3	Q9UM47-1.2	P226E	Pathogenic	0.544
NOTCH3	Q9UM47-1.2	P226F	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	P226G	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	P226H	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	P226I	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	P226K	Pathogenic	0.52
NOTCH3	Q9UM47-1.2	P226L	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	P226M	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	P226N	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	P226Q	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	P226R	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	P226S	Pathogenic	0.545
NOTCH3	Q9UM47-1.2	P226T	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	P226V	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	P226W	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	P226Y	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G227A	Neutral	0.204
NOTCH3	Q9UM47-1.2	G227C	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G227D	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	G227E	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	G227F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	G227H	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	G227I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G227K	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	G227L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G227M	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	G227N	Neutral	0.186
NOTCH3	Q9UM47-1.2	G227P	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	G227Q	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	G227R	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	G227S	Neutral	0.2
NOTCH3	Q9UM47-1.2	G227T	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	G227V	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G227W	Pathogenic	0.788
NOTCH3	Q9UM47-1.2	G227Y	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	F228A	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	F228C	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	F228D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F228E	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F228G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	F228H	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	F228I	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	F228K	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F228L	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	F228M	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	F228N	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F228P	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	F228Q	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F228R	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F228S	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	F228T	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	F228V	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	F228W	Neutral	0.362
NOTCH3	Q9UM47-1.2	F228Y	Neutral	0.029
NOTCH3	Q9UM47-1.2	E229A	Neutral	0.134
NOTCH3	Q9UM47-1.2	E229C	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	E229D	Neutral	0.002
NOTCH3	Q9UM47-1.2	E229F	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	E229G	Neutral	0.394
NOTCH3	Q9UM47-1.2	E229H	Neutral	0.037
NOTCH3	Q9UM47-1.2	E229I	Pathogenic	0.782
NOTCH3	Q9UM47-1.2	E229K	Neutral	0.008
NOTCH3	Q9UM47-1.2	E229L	Pathogenic	0.782
NOTCH3	Q9UM47-1.2	E229M	Neutral	0.44
NOTCH3	Q9UM47-1.2	E229N	Neutral	0.036
NOTCH3	Q9UM47-1.2	E229P	Neutral	0.145
NOTCH3	Q9UM47-1.2	E229Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	E229R	Neutral	0.033
NOTCH3	Q9UM47-1.2	E229S	Neutral	0.033
NOTCH3	Q9UM47-1.2	E229T	Neutral	0.146
NOTCH3	Q9UM47-1.2	E229V	Neutral	0.45
NOTCH3	Q9UM47-1.2	E229W	Pathogenic	0.756
NOTCH3	Q9UM47-1.2	E229Y	Neutral	0.423
NOTCH3	Q9UM47-1.2	G230A	Neutral	0.205
NOTCH3	Q9UM47-1.2	G230C	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G230D	Pathogenic	0.518
NOTCH3	Q9UM47-1.2	G230E	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	G230F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	G230H	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	G230I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G230K	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	G230L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G230M	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	G230N	Neutral	0.188
NOTCH3	Q9UM47-1.2	G230P	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	G230Q	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	G230R	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	G230S	Neutral	0.201
NOTCH3	Q9UM47-1.2	G230T	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G230V	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G230W	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	G230Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	Q231A	Neutral	0.121
NOTCH3	Q9UM47-1.2	Q231C	Pathogenic	0.756
NOTCH3	Q9UM47-1.2	Q231D	Neutral	0.032
NOTCH3	Q9UM47-1.2	Q231E	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q231F	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	Q231G	Neutral	0.368
NOTCH3	Q9UM47-1.2	Q231H	Neutral	0.034
NOTCH3	Q9UM47-1.2	Q231I	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	Q231K	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q231L	Neutral	0.423
NOTCH3	Q9UM47-1.2	Q231M	Neutral	0.034
NOTCH3	Q9UM47-1.2	Q231N	Neutral	0.033
NOTCH3	Q9UM47-1.2	Q231P	Neutral	0.131
NOTCH3	Q9UM47-1.2	Q231R	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q231S	Neutral	0.03
NOTCH3	Q9UM47-1.2	Q231T	Neutral	0.132
NOTCH3	Q9UM47-1.2	Q231V	Neutral	0.423
NOTCH3	Q9UM47-1.2	Q231W	Neutral	0.388
NOTCH3	Q9UM47-1.2	Q231Y	Neutral	0.13
NOTCH3	Q9UM47-1.2	N232A	Pathogenic	0.673
NOTCH3	Q9UM47-1.2	N232C	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	N232D	Neutral	0.023
NOTCH3	Q9UM47-1.2	N232E	Neutral	0.095
NOTCH3	Q9UM47-1.2	N232F	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	N232G	Neutral	0.084
NOTCH3	Q9UM47-1.2	N232H	Neutral	0.022
NOTCH3	Q9UM47-1.2	N232I	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	N232K	Neutral	0.087
NOTCH3	Q9UM47-1.2	N232L	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	N232M	Pathogenic	0.675
NOTCH3	Q9UM47-1.2	N232P	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	N232Q	Neutral	0.093
NOTCH3	Q9UM47-1.2	N232R	Neutral	0.083
NOTCH3	Q9UM47-1.2	N232S	Neutral	0.022
NOTCH3	Q9UM47-1.2	N232T	Neutral	0.099
NOTCH3	Q9UM47-1.2	N232V	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	N232W	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	N232Y	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	C233A	Neutral	0.462
NOTCH3	Q9UM47-1.2	C233D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C233E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C233F	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	C233G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C233H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C233I	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	C233K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C233L	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	C233M	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	C233N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C233P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C233Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C233R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C233S	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	C233T	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C233V	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	C233W	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	C233Y	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	E234A	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	E234C	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	E234D	Neutral	0.019
NOTCH3	Q9UM47-1.2	E234F	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	E234G	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	E234H	Neutral	0.3
NOTCH3	Q9UM47-1.2	E234I	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	E234K	Neutral	0.081
NOTCH3	Q9UM47-1.2	E234L	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	E234M	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	E234N	Neutral	0.295
NOTCH3	Q9UM47-1.2	E234P	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	E234Q	Neutral	0.02
NOTCH3	Q9UM47-1.2	E234R	Neutral	0.275
NOTCH3	Q9UM47-1.2	E234S	Neutral	0.278
NOTCH3	Q9UM47-1.2	E234T	Pathogenic	0.655
NOTCH3	Q9UM47-1.2	E234V	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	E234W	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	E234Y	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	V235A	Neutral	0.004
NOTCH3	Q9UM47-1.2	V235C	Neutral	0.021
NOTCH3	Q9UM47-1.2	V235D	Neutral	0.315
NOTCH3	Q9UM47-1.2	V235E	Neutral	0.095
NOTCH3	Q9UM47-1.2	V235F	Neutral	0.02
NOTCH3	Q9UM47-1.2	V235G	Neutral	0.279
NOTCH3	Q9UM47-1.2	V235H	Neutral	0.315
NOTCH3	Q9UM47-1.2	V235I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V235K	Neutral	0.087
NOTCH3	Q9UM47-1.2	V235L	Neutral	0.001
NOTCH3	Q9UM47-1.2	V235M	Neutral	0.001
NOTCH3	Q9UM47-1.2	V235N	Neutral	0.319
NOTCH3	Q9UM47-1.2	V235P	Neutral	0.091
NOTCH3	Q9UM47-1.2	V235Q	Neutral	0.093
NOTCH3	Q9UM47-1.2	V235R	Neutral	0.292
NOTCH3	Q9UM47-1.2	V235S	Neutral	0.086
NOTCH3	Q9UM47-1.2	V235T	Neutral	0.005
NOTCH3	Q9UM47-1.2	V235W	Neutral	0.278
NOTCH3	Q9UM47-1.2	V235Y	Neutral	0.02
NOTCH3	Q9UM47-1.2	N236A	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	N236C	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N236D	Neutral	0.125
NOTCH3	Q9UM47-1.2	N236E	Neutral	0.386
NOTCH3	Q9UM47-1.2	N236F	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	N236G	Neutral	0.356
NOTCH3	Q9UM47-1.2	N236H	Neutral	0.118
NOTCH3	Q9UM47-1.2	N236I	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	N236K	Neutral	0.363
NOTCH3	Q9UM47-1.2	N236L	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	N236M	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	N236P	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	N236Q	Neutral	0.382
NOTCH3	Q9UM47-1.2	N236R	Neutral	0.352
NOTCH3	Q9UM47-1.2	N236S	Neutral	0.118
NOTCH3	Q9UM47-1.2	N236T	Neutral	0.397
NOTCH3	Q9UM47-1.2	N236V	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N236W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N236Y	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	V237A	Neutral	0.064
NOTCH3	Q9UM47-1.2	V237C	Neutral	0.25
NOTCH3	Q9UM47-1.2	V237D	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	V237E	Pathogenic	0.62
NOTCH3	Q9UM47-1.2	V237F	Neutral	0.243
NOTCH3	Q9UM47-1.2	V237G	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	V237H	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	V237I	Neutral	0.001
NOTCH3	Q9UM47-1.2	V237K	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	V237L	Neutral	0.016
NOTCH3	Q9UM47-1.2	V237M	Neutral	0.016
NOTCH3	Q9UM47-1.2	V237N	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	V237P	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	V237Q	Pathogenic	0.614
NOTCH3	Q9UM47-1.2	V237R	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	V237S	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	V237T	Neutral	0.07
NOTCH3	Q9UM47-1.2	V237W	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	V237Y	Neutral	0.238
NOTCH3	Q9UM47-1.2	D238A	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	D238C	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	D238E	Neutral	0.024
NOTCH3	Q9UM47-1.2	D238F	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	D238G	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	D238H	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	D238I	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	D238K	Pathogenic	0.679
NOTCH3	Q9UM47-1.2	D238L	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D238M	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	D238N	Neutral	0.106
NOTCH3	Q9UM47-1.2	D238P	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	D238Q	Neutral	0.335
NOTCH3	Q9UM47-1.2	D238R	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	D238S	Neutral	0.34
NOTCH3	Q9UM47-1.2	D238T	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	D238V	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	D238W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D238Y	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	D239A	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	D239C	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D239E	Neutral	0.027
NOTCH3	Q9UM47-1.2	D239F	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	D239G	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	D239H	Pathogenic	0.72
NOTCH3	Q9UM47-1.2	D239I	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	D239K	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	D239L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D239M	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	D239N	Neutral	0.118
NOTCH3	Q9UM47-1.2	D239P	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	D239Q	Neutral	0.364
NOTCH3	Q9UM47-1.2	D239R	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	D239S	Neutral	0.369
NOTCH3	Q9UM47-1.2	D239T	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	D239V	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D239W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D239Y	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	C240A	Neutral	0.472
NOTCH3	Q9UM47-1.2	C240D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C240E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C240F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C240G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C240H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C240I	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	C240K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C240L	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	C240M	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C240N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C240P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C240Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C240R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C240S	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C240T	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C240V	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C240W	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C240Y	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	P241A	Pathogenic	0.62
NOTCH3	Q9UM47-1.2	P241C	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	P241D	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	P241E	Pathogenic	0.625
NOTCH3	Q9UM47-1.2	P241F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	P241G	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	P241H	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	P241I	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	P241K	Pathogenic	0.602
NOTCH3	Q9UM47-1.2	P241L	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	P241M	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	P241N	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	P241Q	Pathogenic	0.62
NOTCH3	Q9UM47-1.2	P241R	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	P241S	Pathogenic	0.626
NOTCH3	Q9UM47-1.2	P241T	Pathogenic	0.638
NOTCH3	Q9UM47-1.2	P241V	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	P241W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	P241Y	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	G242A	Neutral	0.036
NOTCH3	Q9UM47-1.2	G242C	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	G242D	Neutral	0.136
NOTCH3	Q9UM47-1.2	G242E	Neutral	0.401
NOTCH3	Q9UM47-1.2	G242F	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	G242H	Neutral	0.391
NOTCH3	Q9UM47-1.2	G242I	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	G242K	Neutral	0.378
NOTCH3	Q9UM47-1.2	G242L	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	G242M	Pathogenic	0.743
NOTCH3	Q9UM47-1.2	G242N	Neutral	0.033
NOTCH3	Q9UM47-1.2	G242P	Neutral	0.419
NOTCH3	Q9UM47-1.2	G242Q	Neutral	0.395
NOTCH3	Q9UM47-1.2	G242R	Neutral	0.366
NOTCH3	Q9UM47-1.2	G242S	Neutral	0.036
NOTCH3	Q9UM47-1.2	G242T	Neutral	0.415
NOTCH3	Q9UM47-1.2	G242V	Pathogenic	0.756
NOTCH3	Q9UM47-1.2	G242W	Neutral	0.355
NOTCH3	Q9UM47-1.2	G242Y	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	H243A	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	H243C	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	H243D	Pathogenic	0.743
NOTCH3	Q9UM47-1.2	H243E	Neutral	0.404
NOTCH3	Q9UM47-1.2	H243F	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	H243G	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	H243I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	H243K	Pathogenic	0.75
NOTCH3	Q9UM47-1.2	H243L	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	H243M	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	H243N	Neutral	0.124
NOTCH3	Q9UM47-1.2	H243P	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	H243Q	Neutral	0.408
NOTCH3	Q9UM47-1.2	H243R	Neutral	0.386
NOTCH3	Q9UM47-1.2	H243S	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	H243T	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	H243V	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	H243W	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	H243Y	Neutral	0.03
NOTCH3	Q9UM47-1.2	R244A	Neutral	0.028
NOTCH3	Q9UM47-1.2	R244C	Neutral	0.396
NOTCH3	Q9UM47-1.2	R244D	Neutral	0.126
NOTCH3	Q9UM47-1.2	R244E	Neutral	0.007
NOTCH3	Q9UM47-1.2	R244F	Neutral	0.443
NOTCH3	Q9UM47-1.2	R244G	Neutral	0.11
NOTCH3	Q9UM47-1.2	R244H	Neutral	0.008
NOTCH3	Q9UM47-1.2	R244I	Neutral	0.433
NOTCH3	Q9UM47-1.2	R244K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R244L	Neutral	0.143
NOTCH3	Q9UM47-1.2	R244M	Neutral	0.035
NOTCH3	Q9UM47-1.2	R244N	Neutral	0.007
NOTCH3	Q9UM47-1.2	R244P	Neutral	0.127
NOTCH3	Q9UM47-1.2	R244Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	R244S	Neutral	0.029
NOTCH3	Q9UM47-1.2	R244T	Neutral	0.031
NOTCH3	Q9UM47-1.2	R244V	Neutral	0.414
NOTCH3	Q9UM47-1.2	R244W	Neutral	0.442
NOTCH3	Q9UM47-1.2	R244Y	Neutral	0.151
NOTCH3	Q9UM47-1.2	C245A	Neutral	0.464
NOTCH3	Q9UM47-1.2	C245D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C245E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C245F	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	C245G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C245H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C245I	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	C245K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C245L	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	C245M	Pathogenic	0.785
NOTCH3	Q9UM47-1.2	C245N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C245P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C245Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C245R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C245S	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C245T	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C245V	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	C245W	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	C245Y	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	L246A	Neutral	0.017
NOTCH3	Q9UM47-1.2	L246C	Neutral	0.018
NOTCH3	Q9UM47-1.2	L246D	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	L246E	Neutral	0.3
NOTCH3	Q9UM47-1.2	L246F	Neutral	0.005
NOTCH3	Q9UM47-1.2	L246G	Pathogenic	0.605
NOTCH3	Q9UM47-1.2	L246H	Neutral	0.306
NOTCH3	Q9UM47-1.2	L246I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L246K	Neutral	0.087
NOTCH3	Q9UM47-1.2	L246M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L246N	Neutral	0.289
NOTCH3	Q9UM47-1.2	L246P	Neutral	0.282
NOTCH3	Q9UM47-1.2	L246Q	Neutral	0.087
NOTCH3	Q9UM47-1.2	L246R	Neutral	0.083
NOTCH3	Q9UM47-1.2	L246S	Neutral	0.075
NOTCH3	Q9UM47-1.2	L246T	Neutral	0.019
NOTCH3	Q9UM47-1.2	L246V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L246W	Neutral	0.078
NOTCH3	Q9UM47-1.2	L246Y	Neutral	0.02
NOTCH3	Q9UM47-1.2	N247A	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	N247C	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N247D	Neutral	0.125
NOTCH3	Q9UM47-1.2	N247E	Neutral	0.388
NOTCH3	Q9UM47-1.2	N247F	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	N247G	Neutral	0.357
NOTCH3	Q9UM47-1.2	N247H	Neutral	0.119
NOTCH3	Q9UM47-1.2	N247I	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	N247K	Neutral	0.365
NOTCH3	Q9UM47-1.2	N247L	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	N247M	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	N247P	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	N247Q	Neutral	0.384
NOTCH3	Q9UM47-1.2	N247R	Neutral	0.353
NOTCH3	Q9UM47-1.2	N247S	Neutral	0.118
NOTCH3	Q9UM47-1.2	N247T	Neutral	0.398
NOTCH3	Q9UM47-1.2	N247V	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N247W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N247Y	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	G248A	Neutral	0.175
NOTCH3	Q9UM47-1.2	G248C	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	G248D	Neutral	0.469
NOTCH3	Q9UM47-1.2	G248E	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	G248F	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	G248H	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	G248I	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	G248K	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	G248L	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	G248M	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	G248N	Neutral	0.16
NOTCH3	Q9UM47-1.2	G248P	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	G248Q	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	G248R	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	G248S	Neutral	0.171
NOTCH3	Q9UM47-1.2	G248T	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	G248V	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	G248W	Pathogenic	0.755
NOTCH3	Q9UM47-1.2	G248Y	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	G249A	Neutral	0.145
NOTCH3	Q9UM47-1.2	G249C	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	G249D	Neutral	0.414
NOTCH3	Q9UM47-1.2	G249E	Pathogenic	0.75
NOTCH3	Q9UM47-1.2	G249F	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	G249H	Pathogenic	0.743
NOTCH3	Q9UM47-1.2	G249I	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	G249K	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	G249L	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	G249M	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	G249N	Neutral	0.132
NOTCH3	Q9UM47-1.2	G249P	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	G249Q	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	G249R	Pathogenic	0.721
NOTCH3	Q9UM47-1.2	G249S	Neutral	0.142
NOTCH3	Q9UM47-1.2	G249T	Pathogenic	0.761
NOTCH3	Q9UM47-1.2	G249V	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	G249W	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	G249Y	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	T250A	Neutral	0.04
NOTCH3	Q9UM47-1.2	T250C	Neutral	0.171
NOTCH3	Q9UM47-1.2	T250D	Neutral	0.175
NOTCH3	Q9UM47-1.2	T250E	Neutral	0.167
NOTCH3	Q9UM47-1.2	T250F	Neutral	0.453
NOTCH3	Q9UM47-1.2	T250G	Neutral	0.448
NOTCH3	Q9UM47-1.2	T250H	Neutral	0.466
NOTCH3	Q9UM47-1.2	T250I	Neutral	0.16
NOTCH3	Q9UM47-1.2	T250K	Neutral	0.154
NOTCH3	Q9UM47-1.2	T250L	Neutral	0.159
NOTCH3	Q9UM47-1.2	T250M	Neutral	0.159
NOTCH3	Q9UM47-1.2	T250N	Neutral	0.044
NOTCH3	Q9UM47-1.2	T250P	Neutral	0.173
NOTCH3	Q9UM47-1.2	T250Q	Neutral	0.164
NOTCH3	Q9UM47-1.2	T250R	Neutral	0.147
NOTCH3	Q9UM47-1.2	T250S	Neutral	0.009
NOTCH3	Q9UM47-1.2	T250V	Neutral	0.043
NOTCH3	Q9UM47-1.2	T250W	Neutral	0.427
NOTCH3	Q9UM47-1.2	T250Y	Neutral	0.446
NOTCH3	Q9UM47-1.2	C251A	Neutral	0.469
NOTCH3	Q9UM47-1.2	C251D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C251E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C251F	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C251G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C251H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C251I	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	C251K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C251L	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	C251M	Pathogenic	0.788
NOTCH3	Q9UM47-1.2	C251N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C251P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C251Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C251R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C251S	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C251T	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C251V	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	C251W	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	C251Y	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	V252A	Neutral	0.275
NOTCH3	Q9UM47-1.2	V252C	Pathogenic	0.648
NOTCH3	Q9UM47-1.2	V252D	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	V252E	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	V252F	Pathogenic	0.639
NOTCH3	Q9UM47-1.2	V252G	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	V252H	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	V252I	Neutral	0.004
NOTCH3	Q9UM47-1.2	V252K	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	V252L	Neutral	0.082
NOTCH3	Q9UM47-1.2	V252M	Neutral	0.082
NOTCH3	Q9UM47-1.2	V252N	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	V252P	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	V252Q	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	V252R	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	V252S	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	V252T	Neutral	0.295
NOTCH3	Q9UM47-1.2	V252W	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	V252Y	Pathogenic	0.633
NOTCH3	Q9UM47-1.2	D253A	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	D253C	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D253E	Neutral	0.029
NOTCH3	Q9UM47-1.2	D253F	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D253G	Pathogenic	0.721
NOTCH3	Q9UM47-1.2	D253H	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	D253I	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D253K	Pathogenic	0.72
NOTCH3	Q9UM47-1.2	D253L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D253M	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D253N	Neutral	0.126
NOTCH3	Q9UM47-1.2	D253P	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	D253Q	Neutral	0.38
NOTCH3	Q9UM47-1.2	D253R	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	D253S	Neutral	0.385
NOTCH3	Q9UM47-1.2	D253T	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	D253V	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D253W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D253Y	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	G254A	Neutral	0.175
NOTCH3	Q9UM47-1.2	G254C	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	G254D	Neutral	0.469
NOTCH3	Q9UM47-1.2	G254E	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	G254F	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	G254H	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	G254I	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	G254K	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	G254L	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	G254M	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	G254N	Neutral	0.16
NOTCH3	Q9UM47-1.2	G254P	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	G254Q	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	G254R	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	G254S	Neutral	0.171
NOTCH3	Q9UM47-1.2	G254T	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	G254V	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	G254W	Pathogenic	0.755
NOTCH3	Q9UM47-1.2	G254Y	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	V255A	Neutral	0.383
NOTCH3	Q9UM47-1.2	V255C	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	V255D	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	V255E	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	V255F	Pathogenic	0.744
NOTCH3	Q9UM47-1.2	V255G	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	V255H	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	V255I	Neutral	0.007
NOTCH3	Q9UM47-1.2	V255K	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	V255L	Neutral	0.127
NOTCH3	Q9UM47-1.2	V255M	Neutral	0.127
NOTCH3	Q9UM47-1.2	V255N	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	V255P	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	V255Q	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	V255R	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	V255S	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	V255T	Neutral	0.407
NOTCH3	Q9UM47-1.2	V255W	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	V255Y	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	N256A	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	N256C	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N256D	Neutral	0.128
NOTCH3	Q9UM47-1.2	N256E	Neutral	0.392
NOTCH3	Q9UM47-1.2	N256F	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	N256G	Neutral	0.361
NOTCH3	Q9UM47-1.2	N256H	Neutral	0.121
NOTCH3	Q9UM47-1.2	N256I	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	N256K	Neutral	0.369
NOTCH3	Q9UM47-1.2	N256L	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	N256M	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	N256P	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	N256Q	Neutral	0.388
NOTCH3	Q9UM47-1.2	N256R	Neutral	0.358
NOTCH3	Q9UM47-1.2	N256S	Neutral	0.12
NOTCH3	Q9UM47-1.2	N256T	Neutral	0.403
NOTCH3	Q9UM47-1.2	N256V	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N256W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N256Y	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	T257A	Neutral	0.28
NOTCH3	Q9UM47-1.2	T257C	Pathogenic	0.657
NOTCH3	Q9UM47-1.2	T257D	Pathogenic	0.662
NOTCH3	Q9UM47-1.2	T257E	Pathogenic	0.65
NOTCH3	Q9UM47-1.2	T257F	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	T257G	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	T257H	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	T257I	Pathogenic	0.638
NOTCH3	Q9UM47-1.2	T257K	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	T257L	Pathogenic	0.638
NOTCH3	Q9UM47-1.2	T257M	Pathogenic	0.637
NOTCH3	Q9UM47-1.2	T257N	Neutral	0.3
NOTCH3	Q9UM47-1.2	T257P	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	T257Q	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	T257R	Pathogenic	0.616
NOTCH3	Q9UM47-1.2	T257S	Neutral	0.081
NOTCH3	Q9UM47-1.2	T257V	Neutral	0.293
NOTCH3	Q9UM47-1.2	T257W	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	T257Y	Pathogenic	0.882
NOTCH3	Q9UM47-1.2	Y258A	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	Y258C	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	Y258D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	Y258E	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	Y258F	Neutral	0.035
NOTCH3	Q9UM47-1.2	Y258G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	Y258H	Neutral	0.133
NOTCH3	Q9UM47-1.2	Y258I	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	Y258K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	Y258L	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	Y258M	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	Y258N	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	Y258P	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	Y258Q	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	Y258R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	Y258S	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	Y258T	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	Y258V	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	Y258W	Neutral	0.134
NOTCH3	Q9UM47-1.2	N259A	Pathogenic	0.863
NOTCH3	Q9UM47-1.2	N259C	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	N259D	Neutral	0.068
NOTCH3	Q9UM47-1.2	N259E	Neutral	0.242
NOTCH3	Q9UM47-1.2	N259F	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	N259G	Neutral	0.219
NOTCH3	Q9UM47-1.2	N259H	Neutral	0.064
NOTCH3	Q9UM47-1.2	N259I	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	N259K	Neutral	0.225
NOTCH3	Q9UM47-1.2	N259L	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	N259M	Pathogenic	0.864
NOTCH3	Q9UM47-1.2	N259P	Pathogenic	0.873
NOTCH3	Q9UM47-1.2	N259Q	Neutral	0.239
NOTCH3	Q9UM47-1.2	N259R	Neutral	0.216
NOTCH3	Q9UM47-1.2	N259S	Neutral	0.064
NOTCH3	Q9UM47-1.2	N259T	Neutral	0.251
NOTCH3	Q9UM47-1.2	N259V	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	N259W	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	N259Y	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	C260A	Neutral	0.462
NOTCH3	Q9UM47-1.2	C260D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C260E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C260F	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	C260G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C260H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C260I	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	C260K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C260L	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	C260M	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	C260N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C260P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C260Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C260R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C260S	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	C260T	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C260V	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	C260W	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	C260Y	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	Q261A	Neutral	0.231
NOTCH3	Q9UM47-1.2	Q261C	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	Q261D	Neutral	0.068
NOTCH3	Q9UM47-1.2	Q261E	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q261F	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	Q261G	Pathogenic	0.56
NOTCH3	Q9UM47-1.2	Q261H	Neutral	0.072
NOTCH3	Q9UM47-1.2	Q261I	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	Q261K	Neutral	0.016
NOTCH3	Q9UM47-1.2	Q261L	Pathogenic	0.615
NOTCH3	Q9UM47-1.2	Q261M	Neutral	0.071
NOTCH3	Q9UM47-1.2	Q261N	Neutral	0.069
NOTCH3	Q9UM47-1.2	Q261P	Neutral	0.248
NOTCH3	Q9UM47-1.2	Q261R	Neutral	0.015
NOTCH3	Q9UM47-1.2	Q261S	Neutral	0.063
NOTCH3	Q9UM47-1.2	Q261T	Neutral	0.25
NOTCH3	Q9UM47-1.2	Q261V	Pathogenic	0.615
NOTCH3	Q9UM47-1.2	Q261W	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	Q261Y	Neutral	0.246
NOTCH3	Q9UM47-1.2	C262A	Neutral	0.467
NOTCH3	Q9UM47-1.2	C262D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C262E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C262F	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C262G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C262H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C262I	Pathogenic	0.788
NOTCH3	Q9UM47-1.2	C262K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C262L	Pathogenic	0.788
NOTCH3	Q9UM47-1.2	C262M	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	C262N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C262P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C262Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C262R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C262S	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C262T	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C262V	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	C262W	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	C262Y	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	P263A	Neutral	0.488
NOTCH3	Q9UM47-1.2	P263C	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	P263D	Pathogenic	0.512
NOTCH3	Q9UM47-1.2	P263E	Neutral	0.494
NOTCH3	Q9UM47-1.2	P263F	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	P263G	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	P263H	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	P263I	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	P263K	Neutral	0.47
NOTCH3	Q9UM47-1.2	P263L	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	P263M	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	P263N	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	P263Q	Neutral	0.488
NOTCH3	Q9UM47-1.2	P263R	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	P263S	Neutral	0.495
NOTCH3	Q9UM47-1.2	P263T	Pathogenic	0.508
NOTCH3	Q9UM47-1.2	P263V	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	P263W	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	P263Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	P264A	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	P264C	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	P264D	Pathogenic	0.654
NOTCH3	Q9UM47-1.2	P264E	Pathogenic	0.638
NOTCH3	Q9UM47-1.2	P264F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	P264G	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	P264H	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	P264I	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	P264K	Pathogenic	0.615
NOTCH3	Q9UM47-1.2	P264L	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	P264M	Pathogenic	0.882
NOTCH3	Q9UM47-1.2	P264N	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	P264Q	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	P264R	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	P264S	Pathogenic	0.638
NOTCH3	Q9UM47-1.2	P264T	Pathogenic	0.65
NOTCH3	Q9UM47-1.2	P264V	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	P264W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	P264Y	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	E265A	Neutral	0.276
NOTCH3	Q9UM47-1.2	E265C	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	E265D	Neutral	0.004
NOTCH3	Q9UM47-1.2	E265F	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	E265G	Pathogenic	0.617
NOTCH3	Q9UM47-1.2	E265H	Neutral	0.087
NOTCH3	Q9UM47-1.2	E265I	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	E265K	Neutral	0.019
NOTCH3	Q9UM47-1.2	E265L	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	E265M	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	E265N	Neutral	0.085
NOTCH3	Q9UM47-1.2	E265P	Neutral	0.295
NOTCH3	Q9UM47-1.2	E265Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	E265R	Neutral	0.078
NOTCH3	Q9UM47-1.2	E265S	Neutral	0.079
NOTCH3	Q9UM47-1.2	E265T	Neutral	0.297
NOTCH3	Q9UM47-1.2	E265V	Pathogenic	0.67
NOTCH3	Q9UM47-1.2	E265W	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	E265Y	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	W266A	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W266C	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	W266D	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W266E	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W266F	Pathogenic	0.669
NOTCH3	Q9UM47-1.2	W266G	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	W266H	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	W266I	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W266K	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W266L	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	W266M	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	W266N	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W266P	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W266Q	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	W266R	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W266S	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W266T	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	W266V	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W266Y	Neutral	0.314
NOTCH3	Q9UM47-1.2	T267A	Neutral	0.411
NOTCH3	Q9UM47-1.2	T267C	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	T267D	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	T267E	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	T267F	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	T267G	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	T267H	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	T267I	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	T267K	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	T267L	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	T267M	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	T267N	Neutral	0.434
NOTCH3	Q9UM47-1.2	T267P	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	T267Q	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	T267R	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	T267S	Neutral	0.136
NOTCH3	Q9UM47-1.2	T267V	Neutral	0.426
NOTCH3	Q9UM47-1.2	T267W	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	T267Y	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	G268A	Neutral	0.223
NOTCH3	Q9UM47-1.2	G268C	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	G268D	Pathogenic	0.544
NOTCH3	Q9UM47-1.2	G268E	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G268F	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G268H	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	G268I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G268K	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	G268L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G268M	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G268N	Neutral	0.204
NOTCH3	Q9UM47-1.2	G268P	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	G268Q	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	G268R	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	G268S	Neutral	0.218
NOTCH3	Q9UM47-1.2	G268T	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	G268V	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G268W	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	G268Y	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	Q269A	Pathogenic	0.663
NOTCH3	Q9UM47-1.2	Q269C	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	Q269D	Neutral	0.321
NOTCH3	Q9UM47-1.2	Q269E	Neutral	0.024
NOTCH3	Q9UM47-1.2	Q269F	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	Q269G	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	Q269H	Neutral	0.337
NOTCH3	Q9UM47-1.2	Q269I	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	Q269K	Neutral	0.095
NOTCH3	Q9UM47-1.2	Q269L	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	Q269M	Neutral	0.334
NOTCH3	Q9UM47-1.2	Q269N	Neutral	0.325
NOTCH3	Q9UM47-1.2	Q269P	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	Q269R	Neutral	0.091
NOTCH3	Q9UM47-1.2	Q269S	Neutral	0.306
NOTCH3	Q9UM47-1.2	Q269T	Pathogenic	0.685
NOTCH3	Q9UM47-1.2	Q269V	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	Q269W	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	Q269Y	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	F270A	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	F270C	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	F270D	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	F270E	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	F270G	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	F270H	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	F270I	Neutral	0.205
NOTCH3	Q9UM47-1.2	F270K	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	F270L	Neutral	0.205
NOTCH3	Q9UM47-1.2	F270M	Neutral	0.206
NOTCH3	Q9UM47-1.2	F270N	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	F270P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	F270Q	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	F270R	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	F270S	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	F270T	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	F270V	Pathogenic	0.523
NOTCH3	Q9UM47-1.2	F270W	Neutral	0.051
NOTCH3	Q9UM47-1.2	F270Y	Neutral	0.003
NOTCH3	Q9UM47-1.2	C271A	Neutral	0.483
NOTCH3	Q9UM47-1.2	C271D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C271E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C271F	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C271G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C271H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C271I	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	C271K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C271L	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	C271M	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	C271N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C271P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C271Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C271R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C271S	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C271T	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C271V	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C271W	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	C271Y	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	T272A	Neutral	0.201
NOTCH3	Q9UM47-1.2	T272C	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	T272D	Pathogenic	0.558
NOTCH3	Q9UM47-1.2	T272E	Pathogenic	0.545
NOTCH3	Q9UM47-1.2	T272F	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	T272G	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	T272H	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	T272I	Pathogenic	0.532
NOTCH3	Q9UM47-1.2	T272K	Pathogenic	0.521
NOTCH3	Q9UM47-1.2	T272L	Pathogenic	0.532
NOTCH3	Q9UM47-1.2	T272M	Pathogenic	0.531
NOTCH3	Q9UM47-1.2	T272N	Neutral	0.217
NOTCH3	Q9UM47-1.2	T272P	Pathogenic	0.556
NOTCH3	Q9UM47-1.2	T272Q	Pathogenic	0.539
NOTCH3	Q9UM47-1.2	T272R	Pathogenic	0.508
NOTCH3	Q9UM47-1.2	T272S	Neutral	0.054
NOTCH3	Q9UM47-1.2	T272V	Neutral	0.211
NOTCH3	Q9UM47-1.2	T272W	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	T272Y	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	E273A	Pathogenic	0.647
NOTCH3	Q9UM47-1.2	E273C	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	E273D	Neutral	0.021
NOTCH3	Q9UM47-1.2	E273F	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	E273G	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	E273H	Neutral	0.313
NOTCH3	Q9UM47-1.2	E273I	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	E273K	Neutral	0.085
NOTCH3	Q9UM47-1.2	E273L	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	E273M	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	E273N	Neutral	0.308
NOTCH3	Q9UM47-1.2	E273P	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	E273Q	Neutral	0.022
NOTCH3	Q9UM47-1.2	E273R	Neutral	0.288
NOTCH3	Q9UM47-1.2	E273S	Neutral	0.291
NOTCH3	Q9UM47-1.2	E273T	Pathogenic	0.669
NOTCH3	Q9UM47-1.2	E273V	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	E273W	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	E273Y	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	D274A	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	D274C	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	D274E	Neutral	0.024
NOTCH3	Q9UM47-1.2	D274F	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	D274G	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	D274H	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	D274I	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	D274K	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	D274L	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D274M	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	D274N	Neutral	0.105
NOTCH3	Q9UM47-1.2	D274P	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	D274Q	Neutral	0.333
NOTCH3	Q9UM47-1.2	D274R	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	D274S	Neutral	0.338
NOTCH3	Q9UM47-1.2	D274T	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	D274V	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	D274W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D274Y	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	V275A	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	V275C	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	V275D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	V275E	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	V275F	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	V275G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	V275H	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	V275I	Neutral	0.011
NOTCH3	Q9UM47-1.2	V275K	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	V275L	Neutral	0.193
NOTCH3	Q9UM47-1.2	V275M	Neutral	0.193
NOTCH3	Q9UM47-1.2	V275N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	V275P	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	V275Q	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	V275R	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	V275S	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	V275T	Pathogenic	0.529
NOTCH3	Q9UM47-1.2	V275W	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	V275Y	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	D276A	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	D276C	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	D276E	Neutral	0.02
NOTCH3	Q9UM47-1.2	D276F	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	D276G	Pathogenic	0.64
NOTCH3	Q9UM47-1.2	D276H	Pathogenic	0.655
NOTCH3	Q9UM47-1.2	D276I	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	D276K	Pathogenic	0.639
NOTCH3	Q9UM47-1.2	D276L	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	D276M	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	D276N	Neutral	0.09
NOTCH3	Q9UM47-1.2	D276P	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	D276Q	Neutral	0.297
NOTCH3	Q9UM47-1.2	D276R	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	D276S	Neutral	0.301
NOTCH3	Q9UM47-1.2	D276T	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	D276V	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	D276W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	D276Y	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	E277A	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	E277C	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	E277D	Neutral	0.043
NOTCH3	Q9UM47-1.2	E277F	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E277G	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	E277H	Neutral	0.494
NOTCH3	Q9UM47-1.2	E277I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E277K	Neutral	0.167
NOTCH3	Q9UM47-1.2	E277L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E277M	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	E277N	Neutral	0.489
NOTCH3	Q9UM47-1.2	E277P	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	E277Q	Neutral	0.046
NOTCH3	Q9UM47-1.2	E277R	Neutral	0.465
NOTCH3	Q9UM47-1.2	E277S	Neutral	0.468
NOTCH3	Q9UM47-1.2	E277T	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	E277V	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	E277W	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	E277Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	C278A	Neutral	0.485
NOTCH3	Q9UM47-1.2	C278D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C278E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C278F	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	C278G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C278H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C278I	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	C278K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C278L	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	C278M	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	C278N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C278P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C278Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C278R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C278S	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C278T	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C278V	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C278W	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	C278Y	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	Q279A	Neutral	0.24
NOTCH3	Q9UM47-1.2	Q279C	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	Q279D	Neutral	0.071
NOTCH3	Q9UM47-1.2	Q279E	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q279F	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	Q279G	Pathogenic	0.571
NOTCH3	Q9UM47-1.2	Q279H	Neutral	0.076
NOTCH3	Q9UM47-1.2	Q279I	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	Q279K	Neutral	0.017
NOTCH3	Q9UM47-1.2	Q279L	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	Q279M	Neutral	0.075
NOTCH3	Q9UM47-1.2	Q279N	Neutral	0.072
NOTCH3	Q9UM47-1.2	Q279P	Neutral	0.257
NOTCH3	Q9UM47-1.2	Q279R	Neutral	0.016
NOTCH3	Q9UM47-1.2	Q279S	Neutral	0.066
NOTCH3	Q9UM47-1.2	Q279T	Neutral	0.259
NOTCH3	Q9UM47-1.2	Q279V	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	Q279W	Pathogenic	0.592
NOTCH3	Q9UM47-1.2	Q279Y	Neutral	0.255
NOTCH3	Q9UM47-1.2	L280A	Neutral	0.476
NOTCH3	Q9UM47-1.2	L280C	Neutral	0.493
NOTCH3	Q9UM47-1.2	L280D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	L280E	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	L280F	Neutral	0.191
NOTCH3	Q9UM47-1.2	L280G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	L280H	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	L280I	Neutral	0.012
NOTCH3	Q9UM47-1.2	L280K	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	L280M	Neutral	0.012
NOTCH3	Q9UM47-1.2	L280N	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	L280P	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	L280Q	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	L280R	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	L280S	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	L280T	Pathogenic	0.501
NOTCH3	Q9UM47-1.2	L280V	Neutral	0.048
NOTCH3	Q9UM47-1.2	L280W	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	L280Y	Pathogenic	0.513
NOTCH3	Q9UM47-1.2	Q281A	Neutral	0.342
NOTCH3	Q9UM47-1.2	Q281C	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	Q281D	Neutral	0.111
NOTCH3	Q9UM47-1.2	Q281E	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q281F	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	Q281G	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	Q281H	Neutral	0.119
NOTCH3	Q9UM47-1.2	Q281I	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	Q281K	Neutral	0.027
NOTCH3	Q9UM47-1.2	Q281L	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	Q281M	Neutral	0.117
NOTCH3	Q9UM47-1.2	Q281N	Neutral	0.113
NOTCH3	Q9UM47-1.2	Q281P	Neutral	0.363
NOTCH3	Q9UM47-1.2	Q281R	Neutral	0.026
NOTCH3	Q9UM47-1.2	Q281S	Neutral	0.104
NOTCH3	Q9UM47-1.2	Q281T	Neutral	0.365
NOTCH3	Q9UM47-1.2	Q281V	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	Q281W	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	Q281Y	Neutral	0.361
NOTCH3	Q9UM47-1.2	P282A	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	P282C	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	P282D	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	P282E	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	P282F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P282G	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	P282H	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	P282I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P282K	Pathogenic	0.671
NOTCH3	Q9UM47-1.2	P282L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P282M	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	P282N	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	P282Q	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	P282R	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	P282S	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	P282T	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	P282V	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	P282W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P282Y	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	N283A	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	N283C	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	N283D	Neutral	0.085
NOTCH3	Q9UM47-1.2	N283E	Neutral	0.291
NOTCH3	Q9UM47-1.2	N283F	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	N283G	Neutral	0.265
NOTCH3	Q9UM47-1.2	N283H	Neutral	0.08
NOTCH3	Q9UM47-1.2	N283I	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	N283K	Neutral	0.271
NOTCH3	Q9UM47-1.2	N283L	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	N283M	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	N283P	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	N283Q	Neutral	0.287
NOTCH3	Q9UM47-1.2	N283R	Neutral	0.261
NOTCH3	Q9UM47-1.2	N283S	Neutral	0.08
NOTCH3	Q9UM47-1.2	N283T	Neutral	0.3
NOTCH3	Q9UM47-1.2	N283V	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	N283W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	N283Y	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	A284C	Neutral	0.164
NOTCH3	Q9UM47-1.2	A284D	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	A284E	Neutral	0.451
NOTCH3	Q9UM47-1.2	A284F	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	A284G	Neutral	0.164
NOTCH3	Q9UM47-1.2	A284H	Pathogenic	0.782
NOTCH3	Q9UM47-1.2	A284I	Neutral	0.438
NOTCH3	Q9UM47-1.2	A284K	Neutral	0.427
NOTCH3	Q9UM47-1.2	A284L	Neutral	0.438
NOTCH3	Q9UM47-1.2	A284M	Neutral	0.437
NOTCH3	Q9UM47-1.2	A284N	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	A284P	Neutral	0.468
NOTCH3	Q9UM47-1.2	A284Q	Neutral	0.445
NOTCH3	Q9UM47-1.2	A284R	Neutral	0.415
NOTCH3	Q9UM47-1.2	A284S	Neutral	0.043
NOTCH3	Q9UM47-1.2	A284T	Neutral	0.16
NOTCH3	Q9UM47-1.2	A284V	Neutral	0.155
NOTCH3	Q9UM47-1.2	A284W	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	A284Y	Pathogenic	0.767
NOTCH3	Q9UM47-1.2	C285A	Neutral	0.485
NOTCH3	Q9UM47-1.2	C285D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C285E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C285F	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	C285G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C285H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C285I	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	C285K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C285L	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	C285M	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	C285N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C285P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C285Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C285R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C285S	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C285T	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C285V	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C285W	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	C285Y	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	H286A	Pathogenic	0.589
NOTCH3	Q9UM47-1.2	H286C	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	H286D	Neutral	0.258
NOTCH3	Q9UM47-1.2	H286E	Neutral	0.075
NOTCH3	Q9UM47-1.2	H286F	Neutral	0.266
NOTCH3	Q9UM47-1.2	H286G	Pathogenic	0.571
NOTCH3	Q9UM47-1.2	H286I	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	H286K	Neutral	0.265
NOTCH3	Q9UM47-1.2	H286L	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	H286M	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	H286N	Neutral	0.017
NOTCH3	Q9UM47-1.2	H286P	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	H286Q	Neutral	0.077
NOTCH3	Q9UM47-1.2	H286R	Neutral	0.07
NOTCH3	Q9UM47-1.2	H286S	Neutral	0.243
NOTCH3	Q9UM47-1.2	H286T	Pathogenic	0.613
NOTCH3	Q9UM47-1.2	H286V	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	H286W	Pathogenic	0.598
NOTCH3	Q9UM47-1.2	H286Y	Neutral	0.004
NOTCH3	Q9UM47-1.2	N287A	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	N287C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N287D	Neutral	0.144
NOTCH3	Q9UM47-1.2	N287E	Neutral	0.426
NOTCH3	Q9UM47-1.2	N287F	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N287G	Neutral	0.395
NOTCH3	Q9UM47-1.2	N287H	Neutral	0.137
NOTCH3	Q9UM47-1.2	N287I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N287K	Neutral	0.403
NOTCH3	Q9UM47-1.2	N287L	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N287M	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	N287P	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	N287Q	Neutral	0.422
NOTCH3	Q9UM47-1.2	N287R	Neutral	0.391
NOTCH3	Q9UM47-1.2	N287S	Neutral	0.136
NOTCH3	Q9UM47-1.2	N287T	Neutral	0.437
NOTCH3	Q9UM47-1.2	N287V	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N287W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N287Y	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	G288A	Neutral	0.215
NOTCH3	Q9UM47-1.2	G288C	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G288D	Pathogenic	0.533
NOTCH3	Q9UM47-1.2	G288E	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G288F	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	G288H	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G288I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G288K	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	G288L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G288M	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G288N	Neutral	0.197
NOTCH3	Q9UM47-1.2	G288P	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	G288Q	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	G288R	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	G288S	Neutral	0.211
NOTCH3	Q9UM47-1.2	G288T	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G288V	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G288W	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	G288Y	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	G289A	Neutral	0.149
NOTCH3	Q9UM47-1.2	G289C	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	G289D	Neutral	0.421
NOTCH3	Q9UM47-1.2	G289E	Pathogenic	0.755
NOTCH3	Q9UM47-1.2	G289F	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	G289H	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	G289I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	G289K	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	G289L	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	G289M	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	G289N	Neutral	0.135
NOTCH3	Q9UM47-1.2	G289P	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	G289Q	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	G289R	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	G289S	Neutral	0.146
NOTCH3	Q9UM47-1.2	G289T	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	G289V	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	G289W	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	G289Y	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	T290A	Neutral	0.421
NOTCH3	Q9UM47-1.2	T290C	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	T290D	Pathogenic	0.785
NOTCH3	Q9UM47-1.2	T290E	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	T290F	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	T290G	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	T290H	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	T290I	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	T290K	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	T290L	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	T290M	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	T290N	Neutral	0.444
NOTCH3	Q9UM47-1.2	T290P	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	T290Q	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	T290R	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	T290S	Neutral	0.141
NOTCH3	Q9UM47-1.2	T290V	Neutral	0.436
NOTCH3	Q9UM47-1.2	T290W	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	T290Y	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	C291A	Neutral	0.474
NOTCH3	Q9UM47-1.2	C291D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C291E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C291F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C291G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C291H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C291I	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	C291K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C291L	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	C291M	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	C291N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C291P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C291Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C291R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C291S	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C291T	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C291V	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C291W	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C291Y	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	F292A	Neutral	0.459
NOTCH3	Q9UM47-1.2	F292C	Neutral	0.476
NOTCH3	Q9UM47-1.2	F292D	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	F292E	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	F292G	Pathogenic	0.782
NOTCH3	Q9UM47-1.2	F292H	Neutral	0.185
NOTCH3	Q9UM47-1.2	F292I	Neutral	0.048
NOTCH3	Q9UM47-1.2	F292K	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	F292L	Neutral	0.048
NOTCH3	Q9UM47-1.2	F292M	Neutral	0.048
NOTCH3	Q9UM47-1.2	F292N	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	F292P	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	F292Q	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	F292R	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	F292S	Neutral	0.465
NOTCH3	Q9UM47-1.2	F292T	Neutral	0.484
NOTCH3	Q9UM47-1.2	F292V	Neutral	0.176
NOTCH3	Q9UM47-1.2	F292W	Neutral	0.01
NOTCH3	Q9UM47-1.2	F292Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	N293A	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	N293C	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	N293D	Neutral	0.111
NOTCH3	Q9UM47-1.2	N293E	Neutral	0.355
NOTCH3	Q9UM47-1.2	N293F	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	N293G	Neutral	0.325
NOTCH3	Q9UM47-1.2	N293H	Neutral	0.105
NOTCH3	Q9UM47-1.2	N293I	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	N293K	Neutral	0.333
NOTCH3	Q9UM47-1.2	N293L	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	N293M	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	N293P	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	N293Q	Neutral	0.351
NOTCH3	Q9UM47-1.2	N293R	Neutral	0.322
NOTCH3	Q9UM47-1.2	N293S	Neutral	0.104
NOTCH3	Q9UM47-1.2	N293T	Neutral	0.365
NOTCH3	Q9UM47-1.2	N293V	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	N293W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	N293Y	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	T294A	Neutral	0.045
NOTCH3	Q9UM47-1.2	T294C	Neutral	0.188
NOTCH3	Q9UM47-1.2	T294D	Neutral	0.191
NOTCH3	Q9UM47-1.2	T294E	Neutral	0.183
NOTCH3	Q9UM47-1.2	T294F	Neutral	0.481
NOTCH3	Q9UM47-1.2	T294G	Neutral	0.475
NOTCH3	Q9UM47-1.2	T294H	Neutral	0.494
NOTCH3	Q9UM47-1.2	T294I	Neutral	0.175
NOTCH3	Q9UM47-1.2	T294K	Neutral	0.169
NOTCH3	Q9UM47-1.2	T294L	Neutral	0.175
NOTCH3	Q9UM47-1.2	T294M	Neutral	0.174
NOTCH3	Q9UM47-1.2	T294N	Neutral	0.049
NOTCH3	Q9UM47-1.2	T294P	Neutral	0.19
NOTCH3	Q9UM47-1.2	T294Q	Neutral	0.179
NOTCH3	Q9UM47-1.2	T294R	Neutral	0.162
NOTCH3	Q9UM47-1.2	T294S	Neutral	0.01
NOTCH3	Q9UM47-1.2	T294V	Neutral	0.048
NOTCH3	Q9UM47-1.2	T294W	Neutral	0.455
NOTCH3	Q9UM47-1.2	T294Y	Neutral	0.473
NOTCH3	Q9UM47-1.2	L295A	Neutral	0.01
NOTCH3	Q9UM47-1.2	L295C	Neutral	0.011
NOTCH3	Q9UM47-1.2	L295D	Pathogenic	0.521
NOTCH3	Q9UM47-1.2	L295E	Neutral	0.204
NOTCH3	Q9UM47-1.2	L295F	Neutral	0.003
NOTCH3	Q9UM47-1.2	L295G	Neutral	0.478
NOTCH3	Q9UM47-1.2	L295H	Neutral	0.208
NOTCH3	Q9UM47-1.2	L295I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L295K	Neutral	0.054
NOTCH3	Q9UM47-1.2	L295M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L295N	Neutral	0.196
NOTCH3	Q9UM47-1.2	L295P	Neutral	0.19
NOTCH3	Q9UM47-1.2	L295Q	Neutral	0.054
NOTCH3	Q9UM47-1.2	L295R	Neutral	0.052
NOTCH3	Q9UM47-1.2	L295S	Neutral	0.046
NOTCH3	Q9UM47-1.2	L295T	Neutral	0.011
NOTCH3	Q9UM47-1.2	L295V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L295W	Neutral	0.048
NOTCH3	Q9UM47-1.2	L295Y	Neutral	0.012
NOTCH3	Q9UM47-1.2	G296A	Neutral	0.203
NOTCH3	Q9UM47-1.2	G296C	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G296D	Pathogenic	0.515
NOTCH3	Q9UM47-1.2	G296E	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	G296F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	G296H	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	G296I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G296K	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	G296L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G296M	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	G296N	Neutral	0.186
NOTCH3	Q9UM47-1.2	G296P	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G296Q	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	G296R	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	G296S	Neutral	0.199
NOTCH3	Q9UM47-1.2	G296T	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	G296V	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G296W	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	G296Y	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	G297A	Neutral	0.078
NOTCH3	Q9UM47-1.2	G297C	Pathogenic	0.882
NOTCH3	Q9UM47-1.2	G297D	Neutral	0.26
NOTCH3	Q9UM47-1.2	G297E	Pathogenic	0.599
NOTCH3	Q9UM47-1.2	G297F	Pathogenic	0.861
NOTCH3	Q9UM47-1.2	G297H	Pathogenic	0.59
NOTCH3	Q9UM47-1.2	G297I	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	G297K	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	G297L	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	G297M	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	G297N	Neutral	0.07
NOTCH3	Q9UM47-1.2	G297P	Pathogenic	0.617
NOTCH3	Q9UM47-1.2	G297Q	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	G297R	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	G297S	Neutral	0.076
NOTCH3	Q9UM47-1.2	G297T	Pathogenic	0.613
NOTCH3	Q9UM47-1.2	G297V	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	G297W	Pathogenic	0.551
NOTCH3	Q9UM47-1.2	G297Y	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	H298A	Pathogenic	0.602
NOTCH3	Q9UM47-1.2	H298C	Pathogenic	0.882
NOTCH3	Q9UM47-1.2	H298D	Neutral	0.268
NOTCH3	Q9UM47-1.2	H298E	Neutral	0.079
NOTCH3	Q9UM47-1.2	H298F	Neutral	0.277
NOTCH3	Q9UM47-1.2	H298G	Pathogenic	0.584
NOTCH3	Q9UM47-1.2	H298I	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	H298K	Neutral	0.276
NOTCH3	Q9UM47-1.2	H298L	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	H298M	Pathogenic	0.644
NOTCH3	Q9UM47-1.2	H298N	Neutral	0.018
NOTCH3	Q9UM47-1.2	H298P	Pathogenic	0.624
NOTCH3	Q9UM47-1.2	H298Q	Neutral	0.08
NOTCH3	Q9UM47-1.2	H298R	Neutral	0.074
NOTCH3	Q9UM47-1.2	H298S	Neutral	0.254
NOTCH3	Q9UM47-1.2	H298T	Pathogenic	0.625
NOTCH3	Q9UM47-1.2	H298V	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	H298W	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	H298Y	Neutral	0.004
NOTCH3	Q9UM47-1.2	S299A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S299C	Neutral	0.021
NOTCH3	Q9UM47-1.2	S299D	Neutral	0.005
NOTCH3	Q9UM47-1.2	S299E	Neutral	0.004
NOTCH3	Q9UM47-1.2	S299F	Neutral	0.075
NOTCH3	Q9UM47-1.2	S299G	Neutral	0.004
NOTCH3	Q9UM47-1.2	S299H	Neutral	0.019
NOTCH3	Q9UM47-1.2	S299I	Neutral	0.079
NOTCH3	Q9UM47-1.2	S299K	Neutral	0.004
NOTCH3	Q9UM47-1.2	S299L	Neutral	0.078
NOTCH3	Q9UM47-1.2	S299M	Neutral	0.018
NOTCH3	Q9UM47-1.2	S299N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S299P	Neutral	0.021
NOTCH3	Q9UM47-1.2	S299Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	S299R	Neutral	0.017
NOTCH3	Q9UM47-1.2	S299T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S299V	Neutral	0.084
NOTCH3	Q9UM47-1.2	S299W	Neutral	0.251
NOTCH3	Q9UM47-1.2	S299Y	Neutral	0.073
NOTCH3	Q9UM47-1.2	C300A	Neutral	0.471
NOTCH3	Q9UM47-1.2	C300D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C300E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C300F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C300G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C300H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C300I	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C300K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C300L	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C300M	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C300N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C300P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C300Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C300R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C300S	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	C300T	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C300V	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	C300W	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C300Y	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	V301A	Neutral	0.369
NOTCH3	Q9UM47-1.2	V301C	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	V301D	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	V301E	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	V301F	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	V301G	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	V301H	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	V301I	Neutral	0.007
NOTCH3	Q9UM47-1.2	V301K	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	V301L	Neutral	0.121
NOTCH3	Q9UM47-1.2	V301M	Neutral	0.121
NOTCH3	Q9UM47-1.2	V301N	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	V301P	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	V301Q	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	V301R	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	V301S	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	V301T	Neutral	0.393
NOTCH3	Q9UM47-1.2	V301W	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	V301Y	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	C302A	Neutral	0.47
NOTCH3	Q9UM47-1.2	C302D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C302E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C302F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C302G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C302H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C302I	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C302K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C302L	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C302M	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	C302N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C302P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C302Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C302R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C302S	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	C302T	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C302V	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	C302W	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C302Y	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	V303A	Pathogenic	0.503
NOTCH3	Q9UM47-1.2	V303C	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	V303D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	V303E	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	V303F	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	V303G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	V303H	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	V303I	Neutral	0.011
NOTCH3	Q9UM47-1.2	V303K	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	V303L	Neutral	0.193
NOTCH3	Q9UM47-1.2	V303M	Neutral	0.192
NOTCH3	Q9UM47-1.2	V303N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	V303P	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	V303Q	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	V303R	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	V303S	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	V303T	Pathogenic	0.528
NOTCH3	Q9UM47-1.2	V303W	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	V303Y	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	N304A	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	N304C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N304D	Neutral	0.136
NOTCH3	Q9UM47-1.2	N304E	Neutral	0.41
NOTCH3	Q9UM47-1.2	N304F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N304G	Neutral	0.379
NOTCH3	Q9UM47-1.2	N304H	Neutral	0.129
NOTCH3	Q9UM47-1.2	N304I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N304K	Neutral	0.387
NOTCH3	Q9UM47-1.2	N304L	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N304M	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	N304P	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	N304Q	Neutral	0.406
NOTCH3	Q9UM47-1.2	N304R	Neutral	0.375
NOTCH3	Q9UM47-1.2	N304S	Neutral	0.129
NOTCH3	Q9UM47-1.2	N304T	Neutral	0.421
NOTCH3	Q9UM47-1.2	N304V	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N304W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N304Y	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	G305A	Neutral	0.22
NOTCH3	Q9UM47-1.2	G305C	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G305D	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	G305E	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	G305F	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G305H	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	G305I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G305K	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	G305L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G305M	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G305N	Neutral	0.202
NOTCH3	Q9UM47-1.2	G305P	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	G305Q	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	G305R	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	G305S	Neutral	0.216
NOTCH3	Q9UM47-1.2	G305T	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	G305V	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G305W	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	G305Y	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	W306A	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W306C	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W306D	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W306E	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W306F	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	W306G	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W306H	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W306I	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W306K	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W306L	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W306M	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	W306N	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W306P	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W306Q	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W306R	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W306S	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W306T	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W306V	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W306Y	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	T307A	Neutral	0.112
NOTCH3	Q9UM47-1.2	T307C	Neutral	0.382
NOTCH3	Q9UM47-1.2	T307D	Neutral	0.387
NOTCH3	Q9UM47-1.2	T307E	Neutral	0.374
NOTCH3	Q9UM47-1.2	T307F	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	T307G	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	T307H	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	T307I	Neutral	0.362
NOTCH3	Q9UM47-1.2	T307K	Neutral	0.352
NOTCH3	Q9UM47-1.2	T307L	Neutral	0.362
NOTCH3	Q9UM47-1.2	T307M	Neutral	0.361
NOTCH3	Q9UM47-1.2	T307N	Neutral	0.121
NOTCH3	Q9UM47-1.2	T307P	Neutral	0.385
NOTCH3	Q9UM47-1.2	T307Q	Neutral	0.369
NOTCH3	Q9UM47-1.2	T307R	Neutral	0.34
NOTCH3	Q9UM47-1.2	T307S	Neutral	0.027
NOTCH3	Q9UM47-1.2	T307V	Neutral	0.118
NOTCH3	Q9UM47-1.2	T307W	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	T307Y	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	G308A	Neutral	0.216
NOTCH3	Q9UM47-1.2	G308C	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G308D	Pathogenic	0.535
NOTCH3	Q9UM47-1.2	G308E	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	G308F	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	G308H	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G308I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G308K	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	G308L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G308M	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G308N	Neutral	0.198
NOTCH3	Q9UM47-1.2	G308P	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	G308Q	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	G308R	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	G308S	Neutral	0.212
NOTCH3	Q9UM47-1.2	G308T	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	G308V	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G308W	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	G308Y	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	E309A	Neutral	0.128
NOTCH3	Q9UM47-1.2	E309C	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	E309D	Neutral	0.002
NOTCH3	Q9UM47-1.2	E309F	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	E309G	Neutral	0.381
NOTCH3	Q9UM47-1.2	E309H	Neutral	0.035
NOTCH3	Q9UM47-1.2	E309I	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	E309K	Neutral	0.007
NOTCH3	Q9UM47-1.2	E309L	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	E309M	Neutral	0.427
NOTCH3	Q9UM47-1.2	E309N	Neutral	0.034
NOTCH3	Q9UM47-1.2	E309P	Neutral	0.138
NOTCH3	Q9UM47-1.2	E309Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	E309R	Neutral	0.031
NOTCH3	Q9UM47-1.2	E309S	Neutral	0.032
NOTCH3	Q9UM47-1.2	E309T	Neutral	0.139
NOTCH3	Q9UM47-1.2	E309V	Neutral	0.437
NOTCH3	Q9UM47-1.2	E309W	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	E309Y	Neutral	0.41
NOTCH3	Q9UM47-1.2	S310A	Neutral	0.003
NOTCH3	Q9UM47-1.2	S310C	Neutral	0.052
NOTCH3	Q9UM47-1.2	S310D	Neutral	0.012
NOTCH3	Q9UM47-1.2	S310E	Neutral	0.011
NOTCH3	Q9UM47-1.2	S310F	Neutral	0.171
NOTCH3	Q9UM47-1.2	S310G	Neutral	0.011
NOTCH3	Q9UM47-1.2	S310H	Neutral	0.046
NOTCH3	Q9UM47-1.2	S310I	Neutral	0.178
NOTCH3	Q9UM47-1.2	S310K	Neutral	0.01
NOTCH3	Q9UM47-1.2	S310L	Neutral	0.177
NOTCH3	Q9UM47-1.2	S310M	Neutral	0.045
NOTCH3	Q9UM47-1.2	S310N	Neutral	0.003
NOTCH3	Q9UM47-1.2	S310P	Neutral	0.051
NOTCH3	Q9UM47-1.2	S310Q	Neutral	0.011
NOTCH3	Q9UM47-1.2	S310R	Neutral	0.041
NOTCH3	Q9UM47-1.2	S310T	Neutral	0.003
NOTCH3	Q9UM47-1.2	S310V	Neutral	0.188
NOTCH3	Q9UM47-1.2	S310W	Neutral	0.459
NOTCH3	Q9UM47-1.2	S310Y	Neutral	0.167
NOTCH3	Q9UM47-1.2	C311A	Neutral	0.471
NOTCH3	Q9UM47-1.2	C311D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C311E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C311F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C311G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C311H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C311I	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C311K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C311L	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C311M	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	C311N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C311P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C311Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C311R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C311S	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	C311T	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C311V	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	C311W	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C311Y	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	S312A	Neutral	0.089
NOTCH3	Q9UM47-1.2	S312C	Pathogenic	0.664
NOTCH3	Q9UM47-1.2	S312D	Neutral	0.298
NOTCH3	Q9UM47-1.2	S312E	Neutral	0.283
NOTCH3	Q9UM47-1.2	S312F	Pathogenic	0.882
NOTCH3	Q9UM47-1.2	S312G	Neutral	0.291
NOTCH3	Q9UM47-1.2	S312H	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	S312I	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	S312K	Neutral	0.264
NOTCH3	Q9UM47-1.2	S312L	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	S312M	Pathogenic	0.631
NOTCH3	Q9UM47-1.2	S312N	Neutral	0.084
NOTCH3	Q9UM47-1.2	S312P	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	S312Q	Neutral	0.279
NOTCH3	Q9UM47-1.2	S312R	Pathogenic	0.608
NOTCH3	Q9UM47-1.2	S312T	Neutral	0.084
NOTCH3	Q9UM47-1.2	S312V	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	S312W	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	S312Y	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	Q313A	Neutral	0.045
NOTCH3	Q9UM47-1.2	Q313C	Pathogenic	0.514
NOTCH3	Q9UM47-1.2	Q313D	Neutral	0.011
NOTCH3	Q9UM47-1.2	Q313E	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q313F	Pathogenic	0.523
NOTCH3	Q9UM47-1.2	Q313G	Neutral	0.166
NOTCH3	Q9UM47-1.2	Q313H	Neutral	0.012
NOTCH3	Q9UM47-1.2	Q313I	Pathogenic	0.533
NOTCH3	Q9UM47-1.2	Q313K	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q313L	Neutral	0.201
NOTCH3	Q9UM47-1.2	Q313M	Neutral	0.012
NOTCH3	Q9UM47-1.2	Q313N	Neutral	0.011
NOTCH3	Q9UM47-1.2	Q313P	Neutral	0.049
NOTCH3	Q9UM47-1.2	Q313R	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q313S	Neutral	0.01
NOTCH3	Q9UM47-1.2	Q313T	Neutral	0.05
NOTCH3	Q9UM47-1.2	Q313V	Neutral	0.201
NOTCH3	Q9UM47-1.2	Q313W	Neutral	0.178
NOTCH3	Q9UM47-1.2	Q313Y	Neutral	0.049
NOTCH3	Q9UM47-1.2	N314A	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	N314C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N314D	Neutral	0.136
NOTCH3	Q9UM47-1.2	N314E	Neutral	0.41
NOTCH3	Q9UM47-1.2	N314F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N314G	Neutral	0.379
NOTCH3	Q9UM47-1.2	N314H	Neutral	0.129
NOTCH3	Q9UM47-1.2	N314I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N314K	Neutral	0.387
NOTCH3	Q9UM47-1.2	N314L	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N314M	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	N314P	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	N314Q	Neutral	0.406
NOTCH3	Q9UM47-1.2	N314R	Neutral	0.375
NOTCH3	Q9UM47-1.2	N314S	Neutral	0.129
NOTCH3	Q9UM47-1.2	N314T	Neutral	0.421
NOTCH3	Q9UM47-1.2	N314V	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N314W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N314Y	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	I315A	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	I315C	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	I315D	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I315E	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I315F	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	I315G	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	I315H	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I315K	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I315L	Neutral	0.101
NOTCH3	Q9UM47-1.2	I315M	Neutral	0.338
NOTCH3	Q9UM47-1.2	I315N	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I315P	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I315Q	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I315R	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I315S	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	I315T	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	I315V	Neutral	0.022
NOTCH3	Q9UM47-1.2	I315W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I315Y	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	D316A	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	D316C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D316E	Neutral	0.03
NOTCH3	Q9UM47-1.2	D316F	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D316G	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	D316H	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	D316I	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D316K	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	D316L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D316M	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D316N	Neutral	0.128
NOTCH3	Q9UM47-1.2	D316P	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	D316Q	Neutral	0.384
NOTCH3	Q9UM47-1.2	D316R	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	D316S	Neutral	0.389
NOTCH3	Q9UM47-1.2	D316T	Pathogenic	0.756
NOTCH3	Q9UM47-1.2	D316V	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D316W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D316Y	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D317A	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	D317C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D317E	Neutral	0.03
NOTCH3	Q9UM47-1.2	D317F	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D317G	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	D317H	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	D317I	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D317K	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	D317L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D317M	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D317N	Neutral	0.129
NOTCH3	Q9UM47-1.2	D317P	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	D317Q	Neutral	0.388
NOTCH3	Q9UM47-1.2	D317R	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	D317S	Neutral	0.393
NOTCH3	Q9UM47-1.2	D317T	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	D317V	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D317W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D317Y	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	C318A	Neutral	0.474
NOTCH3	Q9UM47-1.2	C318D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C318E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C318F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C318G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C318H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C318I	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	C318K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C318L	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	C318M	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	C318N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C318P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C318Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C318R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C318S	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C318T	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C318V	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C318W	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	C318Y	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	A319C	Neutral	0.196
NOTCH3	Q9UM47-1.2	A319D	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	A319E	Pathogenic	0.505
NOTCH3	Q9UM47-1.2	A319F	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	A319G	Neutral	0.196
NOTCH3	Q9UM47-1.2	A319H	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	A319I	Neutral	0.492
NOTCH3	Q9UM47-1.2	A319K	Neutral	0.481
NOTCH3	Q9UM47-1.2	A319L	Neutral	0.491
NOTCH3	Q9UM47-1.2	A319M	Neutral	0.49
NOTCH3	Q9UM47-1.2	A319N	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	A319P	Pathogenic	0.522
NOTCH3	Q9UM47-1.2	A319Q	Neutral	0.499
NOTCH3	Q9UM47-1.2	A319R	Neutral	0.468
NOTCH3	Q9UM47-1.2	A319S	Neutral	0.053
NOTCH3	Q9UM47-1.2	A319T	Neutral	0.191
NOTCH3	Q9UM47-1.2	A319V	Neutral	0.185
NOTCH3	Q9UM47-1.2	A319W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	A319Y	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	T320A	Neutral	0.014
NOTCH3	Q9UM47-1.2	T320C	Neutral	0.067
NOTCH3	Q9UM47-1.2	T320D	Neutral	0.068
NOTCH3	Q9UM47-1.2	T320E	Neutral	0.065
NOTCH3	Q9UM47-1.2	T320F	Neutral	0.223
NOTCH3	Q9UM47-1.2	T320G	Neutral	0.219
NOTCH3	Q9UM47-1.2	T320H	Neutral	0.232
NOTCH3	Q9UM47-1.2	T320I	Neutral	0.062
NOTCH3	Q9UM47-1.2	T320K	Neutral	0.059
NOTCH3	Q9UM47-1.2	T320L	Neutral	0.062
NOTCH3	Q9UM47-1.2	T320M	Neutral	0.061
NOTCH3	Q9UM47-1.2	T320N	Neutral	0.016
NOTCH3	Q9UM47-1.2	T320P	Neutral	0.068
NOTCH3	Q9UM47-1.2	T320Q	Neutral	0.063
NOTCH3	Q9UM47-1.2	T320R	Neutral	0.056
NOTCH3	Q9UM47-1.2	T320S	Neutral	0.003
NOTCH3	Q9UM47-1.2	T320V	Neutral	0.015
NOTCH3	Q9UM47-1.2	T320W	Neutral	0.205
NOTCH3	Q9UM47-1.2	T320Y	Neutral	0.218
NOTCH3	Q9UM47-1.2	A321C	Neutral	0.33
NOTCH3	Q9UM47-1.2	A321D	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	A321E	Pathogenic	0.673
NOTCH3	Q9UM47-1.2	A321F	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	A321G	Neutral	0.33
NOTCH3	Q9UM47-1.2	A321H	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	A321I	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	A321K	Pathogenic	0.651
NOTCH3	Q9UM47-1.2	A321L	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	A321M	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	A321N	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	A321P	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	A321Q	Pathogenic	0.668
NOTCH3	Q9UM47-1.2	A321R	Pathogenic	0.64
NOTCH3	Q9UM47-1.2	A321S	Neutral	0.102
NOTCH3	Q9UM47-1.2	A321T	Neutral	0.323
NOTCH3	Q9UM47-1.2	A321V	Neutral	0.315
NOTCH3	Q9UM47-1.2	A321W	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	A321Y	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	V322A	Neutral	0.019
NOTCH3	Q9UM47-1.2	V322C	Neutral	0.086
NOTCH3	Q9UM47-1.2	V322D	Pathogenic	0.668
NOTCH3	Q9UM47-1.2	V322E	Neutral	0.314
NOTCH3	Q9UM47-1.2	V322F	Neutral	0.083
NOTCH3	Q9UM47-1.2	V322G	Pathogenic	0.629
NOTCH3	Q9UM47-1.2	V322H	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	V322I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V322K	Neutral	0.294
NOTCH3	Q9UM47-1.2	V322L	Neutral	0.005
NOTCH3	Q9UM47-1.2	V322M	Neutral	0.004
NOTCH3	Q9UM47-1.2	V322N	Pathogenic	0.672
NOTCH3	Q9UM47-1.2	V322P	Neutral	0.303
NOTCH3	Q9UM47-1.2	V322Q	Neutral	0.31
NOTCH3	Q9UM47-1.2	V322R	Pathogenic	0.643
NOTCH3	Q9UM47-1.2	V322S	Neutral	0.291
NOTCH3	Q9UM47-1.2	V322T	Neutral	0.021
NOTCH3	Q9UM47-1.2	V322W	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	V322Y	Neutral	0.081
NOTCH3	Q9UM47-1.2	C323A	Neutral	0.488
NOTCH3	Q9UM47-1.2	C323D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C323E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C323F	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	C323G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C323H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C323I	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C323K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C323L	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C323M	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	C323N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C323P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C323Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C323R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C323S	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	C323T	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C323V	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	C323W	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	C323Y	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	F324A	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	F324C	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	F324D	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	F324E	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	F324G	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	F324H	Pathogenic	0.541
NOTCH3	Q9UM47-1.2	F324I	Neutral	0.207
NOTCH3	Q9UM47-1.2	F324K	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	F324L	Neutral	0.207
NOTCH3	Q9UM47-1.2	F324M	Neutral	0.208
NOTCH3	Q9UM47-1.2	F324N	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	F324P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	F324Q	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	F324R	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	F324S	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	F324T	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	F324V	Pathogenic	0.526
NOTCH3	Q9UM47-1.2	F324W	Neutral	0.051
NOTCH3	Q9UM47-1.2	F324Y	Neutral	0.003
NOTCH3	Q9UM47-1.2	H325A	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	H325C	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	H325D	Neutral	0.221
NOTCH3	Q9UM47-1.2	H325E	Neutral	0.063
NOTCH3	Q9UM47-1.2	H325F	Neutral	0.229
NOTCH3	Q9UM47-1.2	H325G	Pathogenic	0.521
NOTCH3	Q9UM47-1.2	H325I	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	H325K	Neutral	0.228
NOTCH3	Q9UM47-1.2	H325L	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	H325M	Pathogenic	0.584
NOTCH3	Q9UM47-1.2	H325N	Neutral	0.014
NOTCH3	Q9UM47-1.2	H325P	Pathogenic	0.562
NOTCH3	Q9UM47-1.2	H325Q	Neutral	0.064
NOTCH3	Q9UM47-1.2	H325R	Neutral	0.058
NOTCH3	Q9UM47-1.2	H325S	Neutral	0.209
NOTCH3	Q9UM47-1.2	H325T	Pathogenic	0.564
NOTCH3	Q9UM47-1.2	H325V	Pathogenic	0.862
NOTCH3	Q9UM47-1.2	H325W	Pathogenic	0.549
NOTCH3	Q9UM47-1.2	H325Y	Neutral	0.003
NOTCH3	Q9UM47-1.2	G326A	Neutral	0.229
NOTCH3	Q9UM47-1.2	G326C	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G326D	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	G326E	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	G326F	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G326H	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G326I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G326K	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	G326L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G326M	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G326N	Neutral	0.211
NOTCH3	Q9UM47-1.2	G326P	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	G326Q	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G326R	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	G326S	Neutral	0.225
NOTCH3	Q9UM47-1.2	G326T	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G326V	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G326W	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	G326Y	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	A327C	Neutral	0.118
NOTCH3	Q9UM47-1.2	A327D	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	A327E	Neutral	0.359
NOTCH3	Q9UM47-1.2	A327F	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	A327G	Neutral	0.118
NOTCH3	Q9UM47-1.2	A327H	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	A327I	Neutral	0.347
NOTCH3	Q9UM47-1.2	A327K	Neutral	0.337
NOTCH3	Q9UM47-1.2	A327L	Neutral	0.347
NOTCH3	Q9UM47-1.2	A327M	Neutral	0.346
NOTCH3	Q9UM47-1.2	A327N	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	A327P	Neutral	0.375
NOTCH3	Q9UM47-1.2	A327Q	Neutral	0.354
NOTCH3	Q9UM47-1.2	A327R	Neutral	0.326
NOTCH3	Q9UM47-1.2	A327S	Neutral	0.03
NOTCH3	Q9UM47-1.2	A327T	Neutral	0.115
NOTCH3	Q9UM47-1.2	A327V	Neutral	0.111
NOTCH3	Q9UM47-1.2	A327W	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	A327Y	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	T328A	Neutral	0.428
NOTCH3	Q9UM47-1.2	T328C	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	T328D	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	T328E	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	T328F	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	T328G	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	T328H	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	T328I	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	T328K	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	T328L	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	T328M	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	T328N	Neutral	0.452
NOTCH3	Q9UM47-1.2	T328P	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	T328Q	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	T328R	Pathogenic	0.755
NOTCH3	Q9UM47-1.2	T328S	Neutral	0.144
NOTCH3	Q9UM47-1.2	T328V	Neutral	0.443
NOTCH3	Q9UM47-1.2	T328W	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	T328Y	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	C329A	Neutral	0.49
NOTCH3	Q9UM47-1.2	C329D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C329E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C329F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C329G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C329H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C329I	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C329K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C329L	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C329M	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C329N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C329P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C329Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C329R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C329S	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C329T	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	C329V	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C329W	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	C329Y	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	H330A	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	H330C	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	H330D	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	H330E	Neutral	0.318
NOTCH3	Q9UM47-1.2	H330F	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	H330G	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	H330I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	H330K	Pathogenic	0.673
NOTCH3	Q9UM47-1.2	H330L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	H330M	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	H330N	Neutral	0.089
NOTCH3	Q9UM47-1.2	H330P	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	H330Q	Neutral	0.321
NOTCH3	Q9UM47-1.2	H330R	Neutral	0.301
NOTCH3	Q9UM47-1.2	H330S	Pathogenic	0.648
NOTCH3	Q9UM47-1.2	H330T	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	H330V	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	H330W	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	H330Y	Neutral	0.021
NOTCH3	Q9UM47-1.2	D331A	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	D331C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D331E	Neutral	0.032
NOTCH3	Q9UM47-1.2	D331F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D331G	Pathogenic	0.743
NOTCH3	Q9UM47-1.2	D331H	Pathogenic	0.755
NOTCH3	Q9UM47-1.2	D331I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D331K	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	D331L	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	D331M	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D331N	Neutral	0.138
NOTCH3	Q9UM47-1.2	D331P	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	D331Q	Neutral	0.406
NOTCH3	Q9UM47-1.2	D331R	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	D331S	Neutral	0.411
NOTCH3	Q9UM47-1.2	D331T	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	D331V	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D331W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D331Y	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	R332A	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	R332C	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	R332D	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	R332E	Pathogenic	0.523
NOTCH3	Q9UM47-1.2	R332F	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R332G	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	R332H	Pathogenic	0.533
NOTCH3	Q9UM47-1.2	R332I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	R332K	Neutral	0.055
NOTCH3	Q9UM47-1.2	R332L	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	R332M	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	R332N	Pathogenic	0.511
NOTCH3	Q9UM47-1.2	R332P	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	R332Q	Neutral	0.198
NOTCH3	Q9UM47-1.2	R332S	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	R332T	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	R332V	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	R332W	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	R332Y	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	V333A	Pathogenic	0.514
NOTCH3	Q9UM47-1.2	V333C	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	V333D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	V333E	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	V333F	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	V333G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	V333H	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	V333I	Neutral	0.012
NOTCH3	Q9UM47-1.2	V333K	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	V333L	Neutral	0.199
NOTCH3	Q9UM47-1.2	V333M	Neutral	0.199
NOTCH3	Q9UM47-1.2	V333N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	V333P	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	V333Q	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	V333R	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	V333S	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	V333T	Pathogenic	0.539
NOTCH3	Q9UM47-1.2	V333W	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	V333Y	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	A334C	Neutral	0.278
NOTCH3	Q9UM47-1.2	A334D	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	A334E	Pathogenic	0.616
NOTCH3	Q9UM47-1.2	A334F	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	A334G	Neutral	0.277
NOTCH3	Q9UM47-1.2	A334H	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	A334I	Pathogenic	0.603
NOTCH3	Q9UM47-1.2	A334K	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	A334L	Pathogenic	0.603
NOTCH3	Q9UM47-1.2	A334M	Pathogenic	0.602
NOTCH3	Q9UM47-1.2	A334N	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	A334P	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	A334Q	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	A334R	Pathogenic	0.581
NOTCH3	Q9UM47-1.2	A334S	Neutral	0.081
NOTCH3	Q9UM47-1.2	A334T	Neutral	0.271
NOTCH3	Q9UM47-1.2	A334V	Neutral	0.264
NOTCH3	Q9UM47-1.2	A334W	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	A334Y	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	S335A	Neutral	0.088
NOTCH3	Q9UM47-1.2	S335C	Pathogenic	0.663
NOTCH3	Q9UM47-1.2	S335D	Neutral	0.297
NOTCH3	Q9UM47-1.2	S335E	Neutral	0.283
NOTCH3	Q9UM47-1.2	S335F	Pathogenic	0.882
NOTCH3	Q9UM47-1.2	S335G	Neutral	0.29
NOTCH3	Q9UM47-1.2	S335H	Pathogenic	0.633
NOTCH3	Q9UM47-1.2	S335I	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	S335K	Neutral	0.263
NOTCH3	Q9UM47-1.2	S335L	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	S335M	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	S335N	Neutral	0.083
NOTCH3	Q9UM47-1.2	S335P	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	S335Q	Neutral	0.278
NOTCH3	Q9UM47-1.2	S335R	Pathogenic	0.608
NOTCH3	Q9UM47-1.2	S335T	Neutral	0.084
NOTCH3	Q9UM47-1.2	S335V	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	S335W	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	S335Y	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	F336A	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	F336C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	F336D	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F336E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F336G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F336H	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	F336I	Pathogenic	0.785
NOTCH3	Q9UM47-1.2	F336K	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F336L	Pathogenic	0.785
NOTCH3	Q9UM47-1.2	F336M	Pathogenic	0.785
NOTCH3	Q9UM47-1.2	F336N	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F336P	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	F336Q	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F336R	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F336S	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	F336T	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	F336V	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	F336W	Neutral	0.429
NOTCH3	Q9UM47-1.2	F336Y	Neutral	0.038
NOTCH3	Q9UM47-1.2	Y337A	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	Y337C	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	Y337D	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	Y337E	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	Y337F	Neutral	0.003
NOTCH3	Q9UM47-1.2	Y337G	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	Y337H	Neutral	0.011
NOTCH3	Q9UM47-1.2	Y337I	Pathogenic	0.514
NOTCH3	Q9UM47-1.2	Y337K	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	Y337L	Pathogenic	0.514
NOTCH3	Q9UM47-1.2	Y337M	Pathogenic	0.513
NOTCH3	Q9UM47-1.2	Y337N	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	Y337P	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	Y337Q	Pathogenic	0.505
NOTCH3	Q9UM47-1.2	Y337R	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	Y337S	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	Y337T	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	Y337V	Neutral	0.495
NOTCH3	Q9UM47-1.2	Y337W	Neutral	0.011
NOTCH3	Q9UM47-1.2	C338A	Neutral	0.49
NOTCH3	Q9UM47-1.2	C338D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C338E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C338F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C338G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C338H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C338I	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C338K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C338L	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C338M	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C338N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C338P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C338Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C338R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C338S	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C338T	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	C338V	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C338W	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	C338Y	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	A339C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A339D	Neutral	0.064
NOTCH3	Q9UM47-1.2	A339E	Neutral	0.014
NOTCH3	Q9UM47-1.2	A339F	Neutral	0.055
NOTCH3	Q9UM47-1.2	A339G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A339H	Neutral	0.058
NOTCH3	Q9UM47-1.2	A339I	Neutral	0.013
NOTCH3	Q9UM47-1.2	A339K	Neutral	0.013
NOTCH3	Q9UM47-1.2	A339L	Neutral	0.013
NOTCH3	Q9UM47-1.2	A339M	Neutral	0.013
NOTCH3	Q9UM47-1.2	A339N	Neutral	0.063
NOTCH3	Q9UM47-1.2	A339P	Neutral	0.015
NOTCH3	Q9UM47-1.2	A339Q	Neutral	0.014
NOTCH3	Q9UM47-1.2	A339R	Neutral	0.012
NOTCH3	Q9UM47-1.2	A339S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A339T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A339V	Neutral	0.003
NOTCH3	Q9UM47-1.2	A339W	Neutral	0.193
NOTCH3	Q9UM47-1.2	A339Y	Neutral	0.054
NOTCH3	Q9UM47-1.2	C340A	Neutral	0.49
NOTCH3	Q9UM47-1.2	C340D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C340E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C340F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C340G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C340H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C340I	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C340K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C340L	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C340M	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C340N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C340P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C340Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C340R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C340S	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C340T	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	C340V	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C340W	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	C340Y	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	P341A	Pathogenic	0.518
NOTCH3	Q9UM47-1.2	P341C	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	P341D	Pathogenic	0.542
NOTCH3	Q9UM47-1.2	P341E	Pathogenic	0.524
NOTCH3	Q9UM47-1.2	P341F	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	P341G	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	P341H	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	P341I	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	P341K	Neutral	0.5
NOTCH3	Q9UM47-1.2	P341L	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	P341M	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	P341N	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	P341Q	Pathogenic	0.518
NOTCH3	Q9UM47-1.2	P341R	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	P341S	Pathogenic	0.525
NOTCH3	Q9UM47-1.2	P341T	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	P341V	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	P341W	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	P341Y	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	M342A	Neutral	0.17
NOTCH3	Q9UM47-1.2	M342C	Neutral	0.18
NOTCH3	Q9UM47-1.2	M342D	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	M342E	Pathogenic	0.525
NOTCH3	Q9UM47-1.2	M342F	Neutral	0.051
NOTCH3	Q9UM47-1.2	M342G	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	M342H	Pathogenic	0.532
NOTCH3	Q9UM47-1.2	M342I	Neutral	0.012
NOTCH3	Q9UM47-1.2	M342K	Neutral	0.198
NOTCH3	Q9UM47-1.2	M342L	Neutral	0.003
NOTCH3	Q9UM47-1.2	M342N	Pathogenic	0.513
NOTCH3	Q9UM47-1.2	M342P	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	M342Q	Neutral	0.051
NOTCH3	Q9UM47-1.2	M342R	Neutral	0.191
NOTCH3	Q9UM47-1.2	M342S	Neutral	0.174
NOTCH3	Q9UM47-1.2	M342T	Neutral	0.185
NOTCH3	Q9UM47-1.2	M342V	Neutral	0.011
NOTCH3	Q9UM47-1.2	M342W	Neutral	0.18
NOTCH3	Q9UM47-1.2	M342Y	Neutral	0.192
NOTCH3	Q9UM47-1.2	G343A	Neutral	0.229
NOTCH3	Q9UM47-1.2	G343C	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G343D	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	G343E	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	G343F	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G343H	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G343I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G343K	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	G343L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G343M	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G343N	Neutral	0.211
NOTCH3	Q9UM47-1.2	G343P	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	G343Q	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G343R	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	G343S	Neutral	0.225
NOTCH3	Q9UM47-1.2	G343T	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G343V	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G343W	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	G343Y	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	K344A	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	K344C	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	K344D	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	K344E	Neutral	0.119
NOTCH3	Q9UM47-1.2	K344F	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	K344G	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	K344H	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	K344I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	K344L	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	K344M	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	K344N	Neutral	0.37
NOTCH3	Q9UM47-1.2	K344P	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	K344Q	Neutral	0.122
NOTCH3	Q9UM47-1.2	K344R	Neutral	0.03
NOTCH3	Q9UM47-1.2	K344S	Neutral	0.35
NOTCH3	Q9UM47-1.2	K344T	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	K344V	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	K344W	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	K344Y	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	T345A	Neutral	0.22
NOTCH3	Q9UM47-1.2	T345C	Pathogenic	0.581
NOTCH3	Q9UM47-1.2	T345D	Pathogenic	0.586
NOTCH3	Q9UM47-1.2	T345E	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	T345F	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	T345G	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	T345H	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	T345I	Pathogenic	0.56
NOTCH3	Q9UM47-1.2	T345K	Pathogenic	0.549
NOTCH3	Q9UM47-1.2	T345L	Pathogenic	0.56
NOTCH3	Q9UM47-1.2	T345M	Pathogenic	0.559
NOTCH3	Q9UM47-1.2	T345N	Neutral	0.236
NOTCH3	Q9UM47-1.2	T345P	Pathogenic	0.584
NOTCH3	Q9UM47-1.2	T345Q	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	T345R	Pathogenic	0.536
NOTCH3	Q9UM47-1.2	T345S	Neutral	0.06
NOTCH3	Q9UM47-1.2	T345V	Neutral	0.23
NOTCH3	Q9UM47-1.2	T345W	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	T345Y	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	G346A	Neutral	0.224
NOTCH3	Q9UM47-1.2	G346C	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	G346D	Pathogenic	0.545
NOTCH3	Q9UM47-1.2	G346E	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	G346F	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G346H	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	G346I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G346K	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	G346L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G346M	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G346N	Neutral	0.205
NOTCH3	Q9UM47-1.2	G346P	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G346Q	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	G346R	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	G346S	Neutral	0.219
NOTCH3	Q9UM47-1.2	G346T	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	G346V	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G346W	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	G346Y	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	L347A	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	L347C	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	L347D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L347E	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L347F	Neutral	0.37
NOTCH3	Q9UM47-1.2	L347G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L347H	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L347I	Neutral	0.029
NOTCH3	Q9UM47-1.2	L347K	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	L347M	Neutral	0.029
NOTCH3	Q9UM47-1.2	L347N	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L347P	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L347Q	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	L347R	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	L347S	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	L347T	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	L347V	Neutral	0.112
NOTCH3	Q9UM47-1.2	L347W	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	L347Y	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	L348A	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	L348C	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	L348D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L348E	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L348F	Neutral	0.37
NOTCH3	Q9UM47-1.2	L348G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L348H	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L348I	Neutral	0.029
NOTCH3	Q9UM47-1.2	L348K	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	L348M	Neutral	0.029
NOTCH3	Q9UM47-1.2	L348N	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L348P	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L348Q	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	L348R	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	L348S	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	L348T	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	L348V	Neutral	0.112
NOTCH3	Q9UM47-1.2	L348W	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	L348Y	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	C349A	Neutral	0.481
NOTCH3	Q9UM47-1.2	C349D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C349E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C349F	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C349G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C349H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C349I	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	C349K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C349L	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	C349M	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	C349N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C349P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C349Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C349R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C349S	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C349T	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C349V	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C349W	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	C349Y	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	H350A	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	H350C	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	H350D	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	H350E	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	H350F	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	H350G	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	H350I	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	H350K	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	H350L	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	H350M	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	H350N	Neutral	0.31
NOTCH3	Q9UM47-1.2	H350P	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	H350Q	Pathogenic	0.686
NOTCH3	Q9UM47-1.2	H350R	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	H350S	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	H350T	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	H350V	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	H350W	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	H350Y	Neutral	0.09
NOTCH3	Q9UM47-1.2	L351A	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	L351C	Pathogenic	0.604
NOTCH3	Q9UM47-1.2	L351D	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	L351E	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	L351F	Neutral	0.27
NOTCH3	Q9UM47-1.2	L351G	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	L351H	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	L351I	Neutral	0.018
NOTCH3	Q9UM47-1.2	L351K	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	L351M	Neutral	0.018
NOTCH3	Q9UM47-1.2	L351N	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	L351P	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	L351Q	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	L351R	Pathogenic	0.882
NOTCH3	Q9UM47-1.2	L351S	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	L351T	Pathogenic	0.612
NOTCH3	Q9UM47-1.2	L351V	Neutral	0.073
NOTCH3	Q9UM47-1.2	L351W	Pathogenic	0.873
NOTCH3	Q9UM47-1.2	L351Y	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	D352A	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	D352C	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	D352E	Neutral	0.01
NOTCH3	Q9UM47-1.2	D352F	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	D352G	Neutral	0.453
NOTCH3	Q9UM47-1.2	D352H	Neutral	0.469
NOTCH3	Q9UM47-1.2	D352I	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	D352K	Neutral	0.451
NOTCH3	Q9UM47-1.2	D352L	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	D352M	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	D352N	Neutral	0.044
NOTCH3	Q9UM47-1.2	D352P	Neutral	0.495
NOTCH3	Q9UM47-1.2	D352Q	Neutral	0.164
NOTCH3	Q9UM47-1.2	D352R	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	D352S	Neutral	0.167
NOTCH3	Q9UM47-1.2	D352T	Neutral	0.493
NOTCH3	Q9UM47-1.2	D352V	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	D352W	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D352Y	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	D353A	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	D353C	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D353E	Neutral	0.027
NOTCH3	Q9UM47-1.2	D353F	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	D353G	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	D353H	Pathogenic	0.72
NOTCH3	Q9UM47-1.2	D353I	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	D353K	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	D353L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D353M	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	D353N	Neutral	0.118
NOTCH3	Q9UM47-1.2	D353P	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	D353Q	Neutral	0.364
NOTCH3	Q9UM47-1.2	D353R	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	D353S	Neutral	0.368
NOTCH3	Q9UM47-1.2	D353T	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	D353V	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D353W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D353Y	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	A354C	Neutral	0.371
NOTCH3	Q9UM47-1.2	A354D	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	A354E	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	A354F	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	A354G	Neutral	0.37
NOTCH3	Q9UM47-1.2	A354H	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	A354I	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	A354K	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	A354L	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	A354M	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	A354N	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	A354P	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	A354Q	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	A354R	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	A354S	Neutral	0.119
NOTCH3	Q9UM47-1.2	A354T	Neutral	0.363
NOTCH3	Q9UM47-1.2	A354V	Neutral	0.354
NOTCH3	Q9UM47-1.2	A354W	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	A354Y	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	C355A	Neutral	0.476
NOTCH3	Q9UM47-1.2	C355D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C355E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C355F	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	C355G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C355H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C355I	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	C355K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C355L	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	C355M	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	C355N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C355P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C355Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C355R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C355S	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C355T	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C355V	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C355W	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	C355Y	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	V356A	Neutral	0.035
NOTCH3	Q9UM47-1.2	V356C	Neutral	0.149
NOTCH3	Q9UM47-1.2	V356D	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	V356E	Neutral	0.461
NOTCH3	Q9UM47-1.2	V356F	Neutral	0.144
NOTCH3	Q9UM47-1.2	V356G	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	V356H	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	V356I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V356K	Neutral	0.437
NOTCH3	Q9UM47-1.2	V356L	Neutral	0.008
NOTCH3	Q9UM47-1.2	V356M	Neutral	0.008
NOTCH3	Q9UM47-1.2	V356N	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	V356P	Neutral	0.448
NOTCH3	Q9UM47-1.2	V356Q	Neutral	0.456
NOTCH3	Q9UM47-1.2	V356R	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	V356S	Neutral	0.433
NOTCH3	Q9UM47-1.2	V356T	Neutral	0.038
NOTCH3	Q9UM47-1.2	V356W	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	V356Y	Neutral	0.141
NOTCH3	Q9UM47-1.2	S357A	Neutral	0.096
NOTCH3	Q9UM47-1.2	S357C	Pathogenic	0.684
NOTCH3	Q9UM47-1.2	S357D	Neutral	0.318
NOTCH3	Q9UM47-1.2	S357E	Neutral	0.302
NOTCH3	Q9UM47-1.2	S357F	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	S357G	Neutral	0.311
NOTCH3	Q9UM47-1.2	S357H	Pathogenic	0.655
NOTCH3	Q9UM47-1.2	S357I	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	S357K	Neutral	0.282
NOTCH3	Q9UM47-1.2	S357L	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	S357M	Pathogenic	0.652
NOTCH3	Q9UM47-1.2	S357N	Neutral	0.091
NOTCH3	Q9UM47-1.2	S357P	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	S357Q	Neutral	0.298
NOTCH3	Q9UM47-1.2	S357R	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	S357T	Neutral	0.092
NOTCH3	Q9UM47-1.2	S357V	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	S357W	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	S357Y	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	N358A	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	N358C	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	N358D	Neutral	0.104
NOTCH3	Q9UM47-1.2	N358E	Neutral	0.339
NOTCH3	Q9UM47-1.2	N358F	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	N358G	Neutral	0.31
NOTCH3	Q9UM47-1.2	N358H	Neutral	0.099
NOTCH3	Q9UM47-1.2	N358I	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	N358K	Neutral	0.317
NOTCH3	Q9UM47-1.2	N358L	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	N358M	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	N358P	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	N358Q	Neutral	0.335
NOTCH3	Q9UM47-1.2	N358R	Neutral	0.307
NOTCH3	Q9UM47-1.2	N358S	Neutral	0.098
NOTCH3	Q9UM47-1.2	N358T	Neutral	0.349
NOTCH3	Q9UM47-1.2	N358V	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	N358W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	N358Y	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	P359A	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	P359C	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	P359D	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	P359E	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	P359F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P359G	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	P359H	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	P359I	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	P359K	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	P359L	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	P359M	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	P359N	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	P359Q	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	P359R	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	P359S	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	P359T	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	P359V	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	P359W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P359Y	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	C360A	Neutral	0.47
NOTCH3	Q9UM47-1.2	C360D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C360E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C360F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C360G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C360H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C360I	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C360K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C360L	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C360M	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	C360N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C360P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C360Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C360R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C360S	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	C360T	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C360V	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	C360W	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C360Y	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	H361A	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	H361C	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	H361D	Neutral	0.357
NOTCH3	Q9UM47-1.2	H361E	Neutral	0.116
NOTCH3	Q9UM47-1.2	H361F	Neutral	0.368
NOTCH3	Q9UM47-1.2	H361G	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	H361I	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	H361K	Neutral	0.367
NOTCH3	Q9UM47-1.2	H361L	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	H361M	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	H361N	Neutral	0.027
NOTCH3	Q9UM47-1.2	H361P	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	H361Q	Neutral	0.117
NOTCH3	Q9UM47-1.2	H361R	Neutral	0.108
NOTCH3	Q9UM47-1.2	H361S	Neutral	0.34
NOTCH3	Q9UM47-1.2	H361T	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	H361V	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	H361W	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	H361Y	Neutral	0.006
NOTCH3	Q9UM47-1.2	E362A	Neutral	0.24
NOTCH3	Q9UM47-1.2	E362C	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	E362D	Neutral	0.004
NOTCH3	Q9UM47-1.2	E362F	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	E362G	Pathogenic	0.572
NOTCH3	Q9UM47-1.2	E362H	Neutral	0.073
NOTCH3	Q9UM47-1.2	E362I	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	E362K	Neutral	0.016
NOTCH3	Q9UM47-1.2	E362L	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	E362M	Pathogenic	0.617
NOTCH3	Q9UM47-1.2	E362N	Neutral	0.072
NOTCH3	Q9UM47-1.2	E362P	Neutral	0.257
NOTCH3	Q9UM47-1.2	E362Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	E362R	Neutral	0.065
NOTCH3	Q9UM47-1.2	E362S	Neutral	0.066
NOTCH3	Q9UM47-1.2	E362T	Neutral	0.259
NOTCH3	Q9UM47-1.2	E362V	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	E362W	Pathogenic	0.864
NOTCH3	Q9UM47-1.2	E362Y	Pathogenic	0.601
NOTCH3	Q9UM47-1.2	D363A	Neutral	0.295
NOTCH3	Q9UM47-1.2	D363C	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	D363E	Neutral	0.001
NOTCH3	Q9UM47-1.2	D363F	Pathogenic	0.641
NOTCH3	Q9UM47-1.2	D363G	Neutral	0.079
NOTCH3	Q9UM47-1.2	D363H	Neutral	0.083
NOTCH3	Q9UM47-1.2	D363I	Pathogenic	0.651
NOTCH3	Q9UM47-1.2	D363K	Neutral	0.078
NOTCH3	Q9UM47-1.2	D363L	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	D363M	Pathogenic	0.65
NOTCH3	Q9UM47-1.2	D363N	Neutral	0.005
NOTCH3	Q9UM47-1.2	D363P	Neutral	0.092
NOTCH3	Q9UM47-1.2	D363Q	Neutral	0.02
NOTCH3	Q9UM47-1.2	D363R	Neutral	0.268
NOTCH3	Q9UM47-1.2	D363S	Neutral	0.02
NOTCH3	Q9UM47-1.2	D363T	Neutral	0.091
NOTCH3	Q9UM47-1.2	D363V	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	D363W	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	D363Y	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	A364C	Neutral	0.095
NOTCH3	Q9UM47-1.2	A364D	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	A364E	Neutral	0.306
NOTCH3	Q9UM47-1.2	A364F	Pathogenic	0.646
NOTCH3	Q9UM47-1.2	A364G	Neutral	0.095
NOTCH3	Q9UM47-1.2	A364H	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	A364I	Neutral	0.294
NOTCH3	Q9UM47-1.2	A364K	Neutral	0.285
NOTCH3	Q9UM47-1.2	A364L	Neutral	0.294
NOTCH3	Q9UM47-1.2	A364M	Neutral	0.293
NOTCH3	Q9UM47-1.2	A364N	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	A364P	Neutral	0.32
NOTCH3	Q9UM47-1.2	A364Q	Neutral	0.301
NOTCH3	Q9UM47-1.2	A364R	Neutral	0.275
NOTCH3	Q9UM47-1.2	A364S	Neutral	0.024
NOTCH3	Q9UM47-1.2	A364T	Neutral	0.093
NOTCH3	Q9UM47-1.2	A364V	Neutral	0.089
NOTCH3	Q9UM47-1.2	A364W	Pathogenic	0.882
NOTCH3	Q9UM47-1.2	A364Y	Pathogenic	0.639
NOTCH3	Q9UM47-1.2	I365A	Neutral	0.091
NOTCH3	Q9UM47-1.2	I365C	Neutral	0.097
NOTCH3	Q9UM47-1.2	I365D	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	I365E	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	I365F	Neutral	0.025
NOTCH3	Q9UM47-1.2	I365G	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	I365H	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	I365K	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	I365L	Neutral	0.001
NOTCH3	Q9UM47-1.2	I365M	Neutral	0.006
NOTCH3	Q9UM47-1.2	I365N	Pathogenic	0.702
NOTCH3	Q9UM47-1.2	I365P	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	I365Q	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	I365R	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	I365S	Neutral	0.32
NOTCH3	Q9UM47-1.2	I365T	Neutral	0.1
NOTCH3	Q9UM47-1.2	I365V	Neutral	0.0
NOTCH3	Q9UM47-1.2	I365W	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	I365Y	Neutral	0.105
NOTCH3	Q9UM47-1.2	C366A	Neutral	0.48
NOTCH3	Q9UM47-1.2	C366D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C366E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C366F	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C366G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C366H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C366I	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	C366K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C366L	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	C366M	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	C366N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C366P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C366Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C366R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C366S	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	C366T	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C366V	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C366W	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	C366Y	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	D367A	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	D367C	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D367E	Neutral	0.028
NOTCH3	Q9UM47-1.2	D367F	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	D367G	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	D367H	Pathogenic	0.722
NOTCH3	Q9UM47-1.2	D367I	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D367K	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	D367L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D367M	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D367N	Neutral	0.119
NOTCH3	Q9UM47-1.2	D367P	Pathogenic	0.743
NOTCH3	Q9UM47-1.2	D367Q	Neutral	0.366
NOTCH3	Q9UM47-1.2	D367R	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	D367S	Neutral	0.371
NOTCH3	Q9UM47-1.2	D367T	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	D367V	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D367W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D367Y	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	T368A	Neutral	0.432
NOTCH3	Q9UM47-1.2	T368C	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	T368D	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	T368E	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	T368F	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	T368G	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	T368H	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	T368I	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	T368K	Pathogenic	0.767
NOTCH3	Q9UM47-1.2	T368L	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	T368M	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	T368N	Neutral	0.455
NOTCH3	Q9UM47-1.2	T368P	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	T368Q	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	T368R	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	T368S	Neutral	0.146
NOTCH3	Q9UM47-1.2	T368V	Neutral	0.447
NOTCH3	Q9UM47-1.2	T368W	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	T368Y	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	N369A	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	N369C	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	N369D	Neutral	0.083
NOTCH3	Q9UM47-1.2	N369E	Neutral	0.287
NOTCH3	Q9UM47-1.2	N369F	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	N369G	Neutral	0.261
NOTCH3	Q9UM47-1.2	N369H	Neutral	0.079
NOTCH3	Q9UM47-1.2	N369I	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	N369K	Neutral	0.267
NOTCH3	Q9UM47-1.2	N369L	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	N369M	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	N369P	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	N369Q	Neutral	0.283
NOTCH3	Q9UM47-1.2	N369R	Neutral	0.257
NOTCH3	Q9UM47-1.2	N369S	Neutral	0.079
NOTCH3	Q9UM47-1.2	N369T	Neutral	0.296
NOTCH3	Q9UM47-1.2	N369V	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	N369W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	N369Y	Pathogenic	0.882
NOTCH3	Q9UM47-1.2	P370A	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	P370C	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	P370D	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	P370E	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	P370F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P370G	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	P370H	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	P370I	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	P370K	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	P370L	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	P370M	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	P370N	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	P370Q	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	P370R	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	P370S	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	P370T	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	P370V	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	P370W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P370Y	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	V371A	Neutral	0.121
NOTCH3	Q9UM47-1.2	V371C	Neutral	0.402
NOTCH3	Q9UM47-1.2	V371D	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	V371E	Pathogenic	0.767
NOTCH3	Q9UM47-1.2	V371F	Neutral	0.393
NOTCH3	Q9UM47-1.2	V371G	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	V371H	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	V371I	Neutral	0.002
NOTCH3	Q9UM47-1.2	V371K	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	V371L	Neutral	0.032
NOTCH3	Q9UM47-1.2	V371M	Neutral	0.031
NOTCH3	Q9UM47-1.2	V371N	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	V371P	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	V371Q	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	V371R	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	V371S	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	V371T	Neutral	0.133
NOTCH3	Q9UM47-1.2	V371W	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	V371Y	Neutral	0.387
NOTCH3	Q9UM47-1.2	N372A	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	N372C	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	N372D	Neutral	0.061
NOTCH3	Q9UM47-1.2	N372E	Neutral	0.224
NOTCH3	Q9UM47-1.2	N372F	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	N372G	Neutral	0.202
NOTCH3	Q9UM47-1.2	N372H	Neutral	0.058
NOTCH3	Q9UM47-1.2	N372I	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	N372K	Neutral	0.207
NOTCH3	Q9UM47-1.2	N372L	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	N372M	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	N372P	Pathogenic	0.861
NOTCH3	Q9UM47-1.2	N372Q	Neutral	0.221
NOTCH3	Q9UM47-1.2	N372R	Neutral	0.199
NOTCH3	Q9UM47-1.2	N372S	Neutral	0.058
NOTCH3	Q9UM47-1.2	N372T	Neutral	0.232
NOTCH3	Q9UM47-1.2	N372V	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	N372W	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	N372Y	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	G373A	Neutral	0.213
NOTCH3	Q9UM47-1.2	G373C	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G373D	Pathogenic	0.53
NOTCH3	Q9UM47-1.2	G373E	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	G373F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	G373H	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	G373I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G373K	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	G373L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G373M	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G373N	Neutral	0.195
NOTCH3	Q9UM47-1.2	G373P	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	G373Q	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G373R	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	G373S	Neutral	0.209
NOTCH3	Q9UM47-1.2	G373T	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G373V	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G373W	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	G373Y	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	R374A	Neutral	0.046
NOTCH3	Q9UM47-1.2	R374C	Pathogenic	0.522
NOTCH3	Q9UM47-1.2	R374D	Neutral	0.194
NOTCH3	Q9UM47-1.2	R374E	Neutral	0.012
NOTCH3	Q9UM47-1.2	R374F	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	R374G	Neutral	0.17
NOTCH3	Q9UM47-1.2	R374H	Neutral	0.013
NOTCH3	Q9UM47-1.2	R374I	Pathogenic	0.56
NOTCH3	Q9UM47-1.2	R374K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R374L	Neutral	0.218
NOTCH3	Q9UM47-1.2	R374M	Neutral	0.058
NOTCH3	Q9UM47-1.2	R374N	Neutral	0.012
NOTCH3	Q9UM47-1.2	R374P	Neutral	0.195
NOTCH3	Q9UM47-1.2	R374Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R374S	Neutral	0.047
NOTCH3	Q9UM47-1.2	R374T	Neutral	0.051
NOTCH3	Q9UM47-1.2	R374V	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	R374W	Pathogenic	0.569
NOTCH3	Q9UM47-1.2	R374Y	Neutral	0.228
NOTCH3	Q9UM47-1.2	A375C	Neutral	0.061
NOTCH3	Q9UM47-1.2	A375D	Pathogenic	0.572
NOTCH3	Q9UM47-1.2	A375E	Neutral	0.215
NOTCH3	Q9UM47-1.2	A375F	Pathogenic	0.531
NOTCH3	Q9UM47-1.2	A375G	Neutral	0.061
NOTCH3	Q9UM47-1.2	A375H	Pathogenic	0.544
NOTCH3	Q9UM47-1.2	A375I	Neutral	0.206
NOTCH3	Q9UM47-1.2	A375K	Neutral	0.199
NOTCH3	Q9UM47-1.2	A375L	Neutral	0.206
NOTCH3	Q9UM47-1.2	A375M	Neutral	0.205
NOTCH3	Q9UM47-1.2	A375N	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	A375P	Neutral	0.227
NOTCH3	Q9UM47-1.2	A375Q	Neutral	0.211
NOTCH3	Q9UM47-1.2	A375R	Neutral	0.191
NOTCH3	Q9UM47-1.2	A375S	Neutral	0.015
NOTCH3	Q9UM47-1.2	A375T	Neutral	0.06
NOTCH3	Q9UM47-1.2	A375V	Neutral	0.057
NOTCH3	Q9UM47-1.2	A375W	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	A375Y	Pathogenic	0.523
NOTCH3	Q9UM47-1.2	I376A	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	I376C	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	I376D	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	I376E	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	I376F	Neutral	0.447
NOTCH3	Q9UM47-1.2	I376G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I376H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	I376K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	I376L	Neutral	0.039
NOTCH3	Q9UM47-1.2	I376M	Neutral	0.157
NOTCH3	Q9UM47-1.2	I376N	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	I376P	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	I376Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	I376R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	I376S	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	I376T	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	I376V	Neutral	0.008
NOTCH3	Q9UM47-1.2	I376W	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	I376Y	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	C377A	Neutral	0.48
NOTCH3	Q9UM47-1.2	C377D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C377E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C377F	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C377G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C377H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C377I	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	C377K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C377L	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	C377M	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	C377N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C377P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C377Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C377R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C377S	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	C377T	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C377V	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C377W	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	C377Y	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	T378A	Neutral	0.23
NOTCH3	Q9UM47-1.2	T378C	Pathogenic	0.596
NOTCH3	Q9UM47-1.2	T378D	Pathogenic	0.601
NOTCH3	Q9UM47-1.2	T378E	Pathogenic	0.588
NOTCH3	Q9UM47-1.2	T378F	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	T378G	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	T378H	Pathogenic	0.862
NOTCH3	Q9UM47-1.2	T378I	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	T378K	Pathogenic	0.564
NOTCH3	Q9UM47-1.2	T378L	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	T378M	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	T378N	Neutral	0.248
NOTCH3	Q9UM47-1.2	T378P	Pathogenic	0.599
NOTCH3	Q9UM47-1.2	T378Q	Pathogenic	0.582
NOTCH3	Q9UM47-1.2	T378R	Pathogenic	0.552
NOTCH3	Q9UM47-1.2	T378S	Neutral	0.063
NOTCH3	Q9UM47-1.2	T378V	Neutral	0.241
NOTCH3	Q9UM47-1.2	T378W	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	T378Y	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	C379A	Neutral	0.48
NOTCH3	Q9UM47-1.2	C379D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C379E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C379F	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C379G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C379H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C379I	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	C379K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C379L	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	C379M	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	C379N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C379P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C379Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C379R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C379S	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	C379T	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C379V	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C379W	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	C379Y	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	P380A	Pathogenic	0.543
NOTCH3	Q9UM47-1.2	P380C	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	P380D	Pathogenic	0.566
NOTCH3	Q9UM47-1.2	P380E	Pathogenic	0.549
NOTCH3	Q9UM47-1.2	P380F	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	P380G	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	P380H	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	P380I	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	P380K	Pathogenic	0.525
NOTCH3	Q9UM47-1.2	P380L	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	P380M	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	P380N	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	P380Q	Pathogenic	0.543
NOTCH3	Q9UM47-1.2	P380R	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	P380S	Pathogenic	0.549
NOTCH3	Q9UM47-1.2	P380T	Pathogenic	0.562
NOTCH3	Q9UM47-1.2	P380V	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	P380W	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	P380Y	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	P381A	Neutral	0.039
NOTCH3	Q9UM47-1.2	P381C	Neutral	0.472
NOTCH3	Q9UM47-1.2	P381D	Neutral	0.042
NOTCH3	Q9UM47-1.2	P381E	Neutral	0.039
NOTCH3	Q9UM47-1.2	P381F	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	P381G	Neutral	0.146
NOTCH3	Q9UM47-1.2	P381H	Neutral	0.152
NOTCH3	Q9UM47-1.2	P381I	Neutral	0.445
NOTCH3	Q9UM47-1.2	P381K	Neutral	0.036
NOTCH3	Q9UM47-1.2	P381L	Neutral	0.445
NOTCH3	Q9UM47-1.2	P381M	Neutral	0.149
NOTCH3	Q9UM47-1.2	P381N	Neutral	0.164
NOTCH3	Q9UM47-1.2	P381Q	Neutral	0.039
NOTCH3	Q9UM47-1.2	P381R	Neutral	0.139
NOTCH3	Q9UM47-1.2	P381S	Neutral	0.04
NOTCH3	Q9UM47-1.2	P381T	Neutral	0.042
NOTCH3	Q9UM47-1.2	P381V	Neutral	0.159
NOTCH3	Q9UM47-1.2	P381W	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	P381Y	Neutral	0.427
NOTCH3	Q9UM47-1.2	G382A	Neutral	0.227
NOTCH3	Q9UM47-1.2	G382C	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G382D	Pathogenic	0.55
NOTCH3	Q9UM47-1.2	G382E	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	G382F	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G382H	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	G382I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G382K	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	G382L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G382M	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G382N	Neutral	0.208
NOTCH3	Q9UM47-1.2	G382P	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G382Q	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G382R	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	G382S	Neutral	0.222
NOTCH3	Q9UM47-1.2	G382T	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G382V	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G382W	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	G382Y	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	F383A	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	F383C	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	F383D	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	F383E	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	F383G	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	F383H	Neutral	0.364
NOTCH3	Q9UM47-1.2	F383I	Neutral	0.113
NOTCH3	Q9UM47-1.2	F383K	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	F383L	Neutral	0.113
NOTCH3	Q9UM47-1.2	F383M	Neutral	0.113
NOTCH3	Q9UM47-1.2	F383N	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	F383P	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	F383Q	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	F383R	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	F383S	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	F383T	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	F383V	Neutral	0.35
NOTCH3	Q9UM47-1.2	F383W	Neutral	0.026
NOTCH3	Q9UM47-1.2	F383Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	T384A	Neutral	0.036
NOTCH3	Q9UM47-1.2	T384C	Neutral	0.156
NOTCH3	Q9UM47-1.2	T384D	Neutral	0.159
NOTCH3	Q9UM47-1.2	T384E	Neutral	0.152
NOTCH3	Q9UM47-1.2	T384F	Neutral	0.426
NOTCH3	Q9UM47-1.2	T384G	Neutral	0.42
NOTCH3	Q9UM47-1.2	T384H	Neutral	0.439
NOTCH3	Q9UM47-1.2	T384I	Neutral	0.145
NOTCH3	Q9UM47-1.2	T384K	Neutral	0.14
NOTCH3	Q9UM47-1.2	T384L	Neutral	0.145
NOTCH3	Q9UM47-1.2	T384M	Neutral	0.145
NOTCH3	Q9UM47-1.2	T384N	Neutral	0.04
NOTCH3	Q9UM47-1.2	T384P	Neutral	0.158
NOTCH3	Q9UM47-1.2	T384Q	Neutral	0.149
NOTCH3	Q9UM47-1.2	T384R	Neutral	0.134
NOTCH3	Q9UM47-1.2	T384S	Neutral	0.008
NOTCH3	Q9UM47-1.2	T384V	Neutral	0.038
NOTCH3	Q9UM47-1.2	T384W	Neutral	0.4
NOTCH3	Q9UM47-1.2	T384Y	Neutral	0.418
NOTCH3	Q9UM47-1.2	G385A	Neutral	0.229
NOTCH3	Q9UM47-1.2	G385C	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G385D	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	G385E	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	G385F	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G385H	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G385I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G385K	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	G385L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G385M	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G385N	Neutral	0.21
NOTCH3	Q9UM47-1.2	G385P	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	G385Q	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G385R	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	G385S	Neutral	0.224
NOTCH3	Q9UM47-1.2	G385T	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G385V	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G385W	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	G385Y	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G386A	Neutral	0.003
NOTCH3	Q9UM47-1.2	G386C	Neutral	0.197
NOTCH3	Q9UM47-1.2	G386D	Neutral	0.011
NOTCH3	Q9UM47-1.2	G386E	Neutral	0.047
NOTCH3	Q9UM47-1.2	G386F	Neutral	0.169
NOTCH3	Q9UM47-1.2	G386H	Neutral	0.045
NOTCH3	Q9UM47-1.2	G386I	Neutral	0.492
NOTCH3	Q9UM47-1.2	G386K	Neutral	0.043
NOTCH3	Q9UM47-1.2	G386L	Neutral	0.492
NOTCH3	Q9UM47-1.2	G386M	Neutral	0.175
NOTCH3	Q9UM47-1.2	G386N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G386P	Neutral	0.05
NOTCH3	Q9UM47-1.2	G386Q	Neutral	0.046
NOTCH3	Q9UM47-1.2	G386R	Neutral	0.041
NOTCH3	Q9UM47-1.2	G386S	Neutral	0.003
NOTCH3	Q9UM47-1.2	G386T	Neutral	0.049
NOTCH3	Q9UM47-1.2	G386V	Neutral	0.186
NOTCH3	Q9UM47-1.2	G386W	Neutral	0.039
NOTCH3	Q9UM47-1.2	G386Y	Neutral	0.165
NOTCH3	Q9UM47-1.2	A387C	Neutral	0.064
NOTCH3	Q9UM47-1.2	A387D	Pathogenic	0.581
NOTCH3	Q9UM47-1.2	A387E	Neutral	0.221
NOTCH3	Q9UM47-1.2	A387F	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	A387G	Neutral	0.063
NOTCH3	Q9UM47-1.2	A387H	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	A387I	Neutral	0.212
NOTCH3	Q9UM47-1.2	A387K	Neutral	0.205
NOTCH3	Q9UM47-1.2	A387L	Neutral	0.212
NOTCH3	Q9UM47-1.2	A387M	Neutral	0.211
NOTCH3	Q9UM47-1.2	A387N	Pathogenic	0.576
NOTCH3	Q9UM47-1.2	A387P	Neutral	0.233
NOTCH3	Q9UM47-1.2	A387Q	Neutral	0.217
NOTCH3	Q9UM47-1.2	A387R	Neutral	0.197
NOTCH3	Q9UM47-1.2	A387S	Neutral	0.015
NOTCH3	Q9UM47-1.2	A387T	Neutral	0.062
NOTCH3	Q9UM47-1.2	A387V	Neutral	0.059
NOTCH3	Q9UM47-1.2	A387W	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	A387Y	Pathogenic	0.532
NOTCH3	Q9UM47-1.2	C388A	Neutral	0.47
NOTCH3	Q9UM47-1.2	C388D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C388E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C388F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C388G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C388H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C388I	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C388K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C388L	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C388M	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	C388N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C388P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C388Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C388R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C388S	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	C388T	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C388V	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	C388W	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C388Y	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	D389A	Neutral	0.146
NOTCH3	Q9UM47-1.2	D389C	Neutral	0.457
NOTCH3	Q9UM47-1.2	D389E	Neutral	0.0
NOTCH3	Q9UM47-1.2	D389F	Neutral	0.421
NOTCH3	Q9UM47-1.2	D389G	Neutral	0.034
NOTCH3	Q9UM47-1.2	D389H	Neutral	0.036
NOTCH3	Q9UM47-1.2	D389I	Neutral	0.432
NOTCH3	Q9UM47-1.2	D389K	Neutral	0.033
NOTCH3	Q9UM47-1.2	D389L	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	D389M	Neutral	0.431
NOTCH3	Q9UM47-1.2	D389N	Neutral	0.002
NOTCH3	Q9UM47-1.2	D389P	Neutral	0.039
NOTCH3	Q9UM47-1.2	D389Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	D389R	Neutral	0.13
NOTCH3	Q9UM47-1.2	D389S	Neutral	0.008
NOTCH3	Q9UM47-1.2	D389T	Neutral	0.039
NOTCH3	Q9UM47-1.2	D389V	Neutral	0.449
NOTCH3	Q9UM47-1.2	D389W	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	D389Y	Neutral	0.414
NOTCH3	Q9UM47-1.2	Q390A	Neutral	0.28
NOTCH3	Q9UM47-1.2	Q390C	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	Q390D	Neutral	0.086
NOTCH3	Q9UM47-1.2	Q390E	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q390F	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	Q390G	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	Q390H	Neutral	0.092
NOTCH3	Q9UM47-1.2	Q390I	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	Q390K	Neutral	0.02
NOTCH3	Q9UM47-1.2	Q390L	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	Q390M	Neutral	0.09
NOTCH3	Q9UM47-1.2	Q390N	Neutral	0.087
NOTCH3	Q9UM47-1.2	Q390P	Neutral	0.299
NOTCH3	Q9UM47-1.2	Q390R	Neutral	0.019
NOTCH3	Q9UM47-1.2	Q390S	Neutral	0.08
NOTCH3	Q9UM47-1.2	Q390T	Neutral	0.301
NOTCH3	Q9UM47-1.2	Q390V	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	Q390W	Pathogenic	0.641
NOTCH3	Q9UM47-1.2	Q390Y	Neutral	0.297
NOTCH3	Q9UM47-1.2	D391A	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	D391C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D391E	Neutral	0.031
NOTCH3	Q9UM47-1.2	D391F	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D391G	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	D391H	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	D391I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D391K	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	D391L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D391M	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D391N	Neutral	0.132
NOTCH3	Q9UM47-1.2	D391P	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	D391Q	Neutral	0.394
NOTCH3	Q9UM47-1.2	D391R	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	D391S	Neutral	0.399
NOTCH3	Q9UM47-1.2	D391T	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	D391V	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D391W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D391Y	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	V392A	Neutral	0.16
NOTCH3	Q9UM47-1.2	V392C	Neutral	0.482
NOTCH3	Q9UM47-1.2	V392D	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	V392E	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	V392F	Neutral	0.472
NOTCH3	Q9UM47-1.2	V392G	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	V392H	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	V392I	Neutral	0.002
NOTCH3	Q9UM47-1.2	V392K	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	V392L	Neutral	0.043
NOTCH3	Q9UM47-1.2	V392M	Neutral	0.043
NOTCH3	Q9UM47-1.2	V392N	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	V392P	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	V392Q	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	V392R	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	V392S	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	V392T	Neutral	0.174
NOTCH3	Q9UM47-1.2	V392W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	V392Y	Neutral	0.465
NOTCH3	Q9UM47-1.2	D393A	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	D393C	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D393E	Neutral	0.026
NOTCH3	Q9UM47-1.2	D393F	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	D393G	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	D393H	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	D393I	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	D393K	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	D393L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D393M	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	D393N	Neutral	0.112
NOTCH3	Q9UM47-1.2	D393P	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	D393Q	Neutral	0.351
NOTCH3	Q9UM47-1.2	D393R	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	D393S	Neutral	0.355
NOTCH3	Q9UM47-1.2	D393T	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	D393V	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D393W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D393Y	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	E394A	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	E394C	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	E394D	Neutral	0.043
NOTCH3	Q9UM47-1.2	E394F	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E394G	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	E394H	Neutral	0.49
NOTCH3	Q9UM47-1.2	E394I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E394K	Neutral	0.165
NOTCH3	Q9UM47-1.2	E394L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E394M	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	E394N	Neutral	0.485
NOTCH3	Q9UM47-1.2	E394P	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	E394Q	Neutral	0.045
NOTCH3	Q9UM47-1.2	E394R	Neutral	0.46
NOTCH3	Q9UM47-1.2	E394S	Neutral	0.464
NOTCH3	Q9UM47-1.2	E394T	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	E394V	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	E394W	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	E394Y	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	C395A	Neutral	0.48
NOTCH3	Q9UM47-1.2	C395D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C395E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C395F	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C395G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C395H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C395I	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	C395K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C395L	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	C395M	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	C395N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C395P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C395Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C395R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C395S	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	C395T	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C395V	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C395W	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	C395Y	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	S396A	Neutral	0.012
NOTCH3	Q9UM47-1.2	S396C	Neutral	0.204
NOTCH3	Q9UM47-1.2	S396D	Neutral	0.052
NOTCH3	Q9UM47-1.2	S396E	Neutral	0.049
NOTCH3	Q9UM47-1.2	S396F	Neutral	0.493
NOTCH3	Q9UM47-1.2	S396G	Neutral	0.051
NOTCH3	Q9UM47-1.2	S396H	Neutral	0.184
NOTCH3	Q9UM47-1.2	S396I	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	S396K	Neutral	0.045
NOTCH3	Q9UM47-1.2	S396L	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	S396M	Neutral	0.182
NOTCH3	Q9UM47-1.2	S396N	Neutral	0.012
NOTCH3	Q9UM47-1.2	S396P	Neutral	0.201
NOTCH3	Q9UM47-1.2	S396Q	Neutral	0.048
NOTCH3	Q9UM47-1.2	S396R	Neutral	0.168
NOTCH3	Q9UM47-1.2	S396T	Neutral	0.012
NOTCH3	Q9UM47-1.2	S396V	Pathogenic	0.521
NOTCH3	Q9UM47-1.2	S396W	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	S396Y	Neutral	0.486
NOTCH3	Q9UM47-1.2	I397A	Neutral	0.212
NOTCH3	Q9UM47-1.2	I397C	Neutral	0.223
NOTCH3	Q9UM47-1.2	I397D	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	I397E	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	I397F	Neutral	0.065
NOTCH3	Q9UM47-1.2	I397G	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	I397H	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	I397K	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	I397L	Neutral	0.003
NOTCH3	Q9UM47-1.2	I397M	Neutral	0.016
NOTCH3	Q9UM47-1.2	I397N	Pathogenic	0.862
NOTCH3	Q9UM47-1.2	I397P	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	I397Q	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	I397R	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	I397S	Pathogenic	0.556
NOTCH3	Q9UM47-1.2	I397T	Neutral	0.229
NOTCH3	Q9UM47-1.2	I397V	Neutral	0.001
NOTCH3	Q9UM47-1.2	I397W	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	I397Y	Neutral	0.237
NOTCH3	Q9UM47-1.2	G398A	Neutral	0.052
NOTCH3	Q9UM47-1.2	G398C	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	G398D	Neutral	0.187
NOTCH3	Q9UM47-1.2	G398E	Neutral	0.494
NOTCH3	Q9UM47-1.2	G398F	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	G398H	Neutral	0.484
NOTCH3	Q9UM47-1.2	G398I	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	G398K	Neutral	0.47
NOTCH3	Q9UM47-1.2	G398L	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	G398M	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	G398N	Neutral	0.047
NOTCH3	Q9UM47-1.2	G398P	Pathogenic	0.513
NOTCH3	Q9UM47-1.2	G398Q	Neutral	0.488
NOTCH3	Q9UM47-1.2	G398R	Neutral	0.457
NOTCH3	Q9UM47-1.2	G398S	Neutral	0.051
NOTCH3	Q9UM47-1.2	G398T	Pathogenic	0.509
NOTCH3	Q9UM47-1.2	G398V	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	G398W	Neutral	0.446
NOTCH3	Q9UM47-1.2	G398Y	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	A399C	Neutral	0.049
NOTCH3	Q9UM47-1.2	A399D	Pathogenic	0.514
NOTCH3	Q9UM47-1.2	A399E	Neutral	0.178
NOTCH3	Q9UM47-1.2	A399F	Neutral	0.472
NOTCH3	Q9UM47-1.2	A399G	Neutral	0.049
NOTCH3	Q9UM47-1.2	A399H	Neutral	0.486
NOTCH3	Q9UM47-1.2	A399I	Neutral	0.17
NOTCH3	Q9UM47-1.2	A399K	Neutral	0.164
NOTCH3	Q9UM47-1.2	A399L	Neutral	0.17
NOTCH3	Q9UM47-1.2	A399M	Neutral	0.17
NOTCH3	Q9UM47-1.2	A399N	Pathogenic	0.509
NOTCH3	Q9UM47-1.2	A399P	Neutral	0.188
NOTCH3	Q9UM47-1.2	A399Q	Neutral	0.175
NOTCH3	Q9UM47-1.2	A399R	Neutral	0.157
NOTCH3	Q9UM47-1.2	A399S	Neutral	0.012
NOTCH3	Q9UM47-1.2	A399T	Neutral	0.048
NOTCH3	Q9UM47-1.2	A399V	Neutral	0.046
NOTCH3	Q9UM47-1.2	A399W	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	A399Y	Neutral	0.465
NOTCH3	Q9UM47-1.2	N400A	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	N400C	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	N400D	Neutral	0.088
NOTCH3	Q9UM47-1.2	N400E	Neutral	0.3
NOTCH3	Q9UM47-1.2	N400F	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	N400G	Neutral	0.273
NOTCH3	Q9UM47-1.2	N400H	Neutral	0.084
NOTCH3	Q9UM47-1.2	N400I	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	N400K	Neutral	0.28
NOTCH3	Q9UM47-1.2	N400L	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	N400M	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	N400P	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	N400Q	Neutral	0.296
NOTCH3	Q9UM47-1.2	N400R	Neutral	0.27
NOTCH3	Q9UM47-1.2	N400S	Neutral	0.083
NOTCH3	Q9UM47-1.2	N400T	Neutral	0.309
NOTCH3	Q9UM47-1.2	N400V	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	N400W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	N400Y	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	P401A	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	P401C	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	P401D	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	P401E	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	P401F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P401G	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	P401H	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	P401I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P401K	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	P401L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P401M	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	P401N	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	P401Q	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	P401R	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	P401S	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	P401T	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	P401V	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	P401W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P401Y	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	C402A	Neutral	0.493
NOTCH3	Q9UM47-1.2	C402D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C402E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C402F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C402G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C402H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C402I	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C402K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C402L	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C402M	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C402N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C402P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C402Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C402R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C402S	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C402T	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C402V	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C402W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C402Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	E403A	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	E403C	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	E403D	Neutral	0.045
NOTCH3	Q9UM47-1.2	E403F	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E403G	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	E403H	Pathogenic	0.503
NOTCH3	Q9UM47-1.2	E403I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	E403K	Neutral	0.172
NOTCH3	Q9UM47-1.2	E403L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	E403M	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	E403N	Neutral	0.497
NOTCH3	Q9UM47-1.2	E403P	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	E403Q	Neutral	0.047
NOTCH3	Q9UM47-1.2	E403R	Neutral	0.473
NOTCH3	Q9UM47-1.2	E403S	Neutral	0.476
NOTCH3	Q9UM47-1.2	E403T	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	E403V	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	E403W	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	E403Y	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	H404A	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	H404C	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H404D	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	H404E	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	H404F	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	H404G	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	H404I	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H404K	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	H404L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H404M	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	H404N	Neutral	0.359
NOTCH3	Q9UM47-1.2	H404P	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	H404Q	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	H404R	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	H404S	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	H404T	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	H404V	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H404W	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	H404Y	Neutral	0.109
NOTCH3	Q9UM47-1.2	L405A	Neutral	0.015
NOTCH3	Q9UM47-1.2	L405C	Neutral	0.016
NOTCH3	Q9UM47-1.2	L405D	Pathogenic	0.609
NOTCH3	Q9UM47-1.2	L405E	Neutral	0.268
NOTCH3	Q9UM47-1.2	L405F	Neutral	0.004
NOTCH3	Q9UM47-1.2	L405G	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	L405H	Neutral	0.273
NOTCH3	Q9UM47-1.2	L405I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L405K	Neutral	0.076
NOTCH3	Q9UM47-1.2	L405M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L405N	Neutral	0.258
NOTCH3	Q9UM47-1.2	L405P	Neutral	0.252
NOTCH3	Q9UM47-1.2	L405Q	Neutral	0.075
NOTCH3	Q9UM47-1.2	L405R	Neutral	0.072
NOTCH3	Q9UM47-1.2	L405S	Neutral	0.065
NOTCH3	Q9UM47-1.2	L405T	Neutral	0.016
NOTCH3	Q9UM47-1.2	L405V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L405W	Neutral	0.067
NOTCH3	Q9UM47-1.2	L405Y	Neutral	0.017
NOTCH3	Q9UM47-1.2	G406A	Neutral	0.232
NOTCH3	Q9UM47-1.2	G406C	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G406D	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	G406E	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	G406F	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G406H	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G406I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G406K	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G406L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G406M	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G406N	Neutral	0.213
NOTCH3	Q9UM47-1.2	G406P	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	G406Q	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	G406R	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	G406S	Neutral	0.227
NOTCH3	Q9UM47-1.2	G406T	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	G406V	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G406W	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	G406Y	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	R407A	Neutral	0.089
NOTCH3	Q9UM47-1.2	R407C	Pathogenic	0.686
NOTCH3	Q9UM47-1.2	R407D	Neutral	0.325
NOTCH3	Q9UM47-1.2	R407E	Neutral	0.024
NOTCH3	Q9UM47-1.2	R407F	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	R407G	Neutral	0.291
NOTCH3	Q9UM47-1.2	R407H	Neutral	0.025
NOTCH3	Q9UM47-1.2	R407I	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	R407K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R407L	Neutral	0.358
NOTCH3	Q9UM47-1.2	R407M	Neutral	0.109
NOTCH3	Q9UM47-1.2	R407N	Neutral	0.023
NOTCH3	Q9UM47-1.2	R407P	Neutral	0.327
NOTCH3	Q9UM47-1.2	R407Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	R407S	Neutral	0.09
NOTCH3	Q9UM47-1.2	R407T	Neutral	0.097
NOTCH3	Q9UM47-1.2	R407V	Pathogenic	0.702
NOTCH3	Q9UM47-1.2	R407W	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	R407Y	Neutral	0.372
NOTCH3	Q9UM47-1.2	C408A	Neutral	0.493
NOTCH3	Q9UM47-1.2	C408D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C408E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C408F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C408G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C408H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C408I	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C408K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C408L	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C408M	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C408N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C408P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C408Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C408R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C408S	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C408T	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C408V	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C408W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C408Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	V409A	Neutral	0.117
NOTCH3	Q9UM47-1.2	V409C	Neutral	0.391
NOTCH3	Q9UM47-1.2	V409D	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	V409E	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	V409F	Neutral	0.382
NOTCH3	Q9UM47-1.2	V409G	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	V409H	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	V409I	Neutral	0.001
NOTCH3	Q9UM47-1.2	V409K	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	V409L	Neutral	0.03
NOTCH3	Q9UM47-1.2	V409M	Neutral	0.03
NOTCH3	Q9UM47-1.2	V409N	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	V409P	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	V409Q	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	V409R	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	V409S	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	V409T	Neutral	0.127
NOTCH3	Q9UM47-1.2	V409W	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	V409Y	Neutral	0.376
NOTCH3	Q9UM47-1.2	N410A	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	N410C	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	N410D	Neutral	0.147
NOTCH3	Q9UM47-1.2	N410E	Neutral	0.433
NOTCH3	Q9UM47-1.2	N410F	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N410G	Neutral	0.401
NOTCH3	Q9UM47-1.2	N410H	Neutral	0.14
NOTCH3	Q9UM47-1.2	N410I	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N410K	Neutral	0.409
NOTCH3	Q9UM47-1.2	N410L	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N410M	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	N410P	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	N410Q	Neutral	0.428
NOTCH3	Q9UM47-1.2	N410R	Neutral	0.397
NOTCH3	Q9UM47-1.2	N410S	Neutral	0.139
NOTCH3	Q9UM47-1.2	N410T	Neutral	0.444
NOTCH3	Q9UM47-1.2	N410V	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	N410W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N410Y	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	T411A	Neutral	0.438
NOTCH3	Q9UM47-1.2	T411C	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	T411D	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	T411E	Pathogenic	0.788
NOTCH3	Q9UM47-1.2	T411F	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	T411G	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	T411H	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	T411I	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	T411K	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	T411L	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	T411M	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	T411N	Neutral	0.461
NOTCH3	Q9UM47-1.2	T411P	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	T411Q	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	T411R	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	T411S	Neutral	0.149
NOTCH3	Q9UM47-1.2	T411V	Neutral	0.453
NOTCH3	Q9UM47-1.2	T411W	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	T411Y	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	Q412A	Neutral	0.044
NOTCH3	Q9UM47-1.2	Q412C	Pathogenic	0.509
NOTCH3	Q9UM47-1.2	Q412D	Neutral	0.011
NOTCH3	Q9UM47-1.2	Q412E	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q412F	Pathogenic	0.518
NOTCH3	Q9UM47-1.2	Q412G	Neutral	0.163
NOTCH3	Q9UM47-1.2	Q412H	Neutral	0.012
NOTCH3	Q9UM47-1.2	Q412I	Pathogenic	0.528
NOTCH3	Q9UM47-1.2	Q412K	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q412L	Neutral	0.197
NOTCH3	Q9UM47-1.2	Q412M	Neutral	0.012
NOTCH3	Q9UM47-1.2	Q412N	Neutral	0.011
NOTCH3	Q9UM47-1.2	Q412P	Neutral	0.048
NOTCH3	Q9UM47-1.2	Q412R	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q412S	Neutral	0.01
NOTCH3	Q9UM47-1.2	Q412T	Neutral	0.049
NOTCH3	Q9UM47-1.2	Q412V	Neutral	0.197
NOTCH3	Q9UM47-1.2	Q412W	Neutral	0.175
NOTCH3	Q9UM47-1.2	Q412Y	Neutral	0.048
NOTCH3	Q9UM47-1.2	G413A	Neutral	0.232
NOTCH3	Q9UM47-1.2	G413C	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G413D	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	G413E	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	G413F	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G413H	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G413I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G413K	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G413L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G413M	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G413N	Neutral	0.213
NOTCH3	Q9UM47-1.2	G413P	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	G413Q	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	G413R	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	G413S	Neutral	0.227
NOTCH3	Q9UM47-1.2	G413T	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	G413V	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G413W	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	G413Y	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	S414A	Neutral	0.049
NOTCH3	Q9UM47-1.2	S414C	Pathogenic	0.51
NOTCH3	Q9UM47-1.2	S414D	Neutral	0.183
NOTCH3	Q9UM47-1.2	S414E	Neutral	0.173
NOTCH3	Q9UM47-1.2	S414F	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	S414G	Neutral	0.178
NOTCH3	Q9UM47-1.2	S414H	Neutral	0.478
NOTCH3	Q9UM47-1.2	S414I	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	S414K	Neutral	0.159
NOTCH3	Q9UM47-1.2	S414L	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	S414M	Neutral	0.474
NOTCH3	Q9UM47-1.2	S414N	Neutral	0.046
NOTCH3	Q9UM47-1.2	S414P	Pathogenic	0.506
NOTCH3	Q9UM47-1.2	S414Q	Neutral	0.17
NOTCH3	Q9UM47-1.2	S414R	Neutral	0.451
NOTCH3	Q9UM47-1.2	S414T	Neutral	0.046
NOTCH3	Q9UM47-1.2	S414V	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	S414W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	S414Y	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	F415A	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	F415C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	F415D	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F415E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F415G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F415H	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	F415I	Pathogenic	0.788
NOTCH3	Q9UM47-1.2	F415K	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F415L	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	F415M	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	F415N	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F415P	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	F415Q	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F415R	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F415S	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	F415T	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	F415V	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	F415W	Neutral	0.435
NOTCH3	Q9UM47-1.2	F415Y	Neutral	0.039
NOTCH3	Q9UM47-1.2	L416A	Neutral	0.01
NOTCH3	Q9UM47-1.2	L416C	Neutral	0.01
NOTCH3	Q9UM47-1.2	L416D	Pathogenic	0.501
NOTCH3	Q9UM47-1.2	L416E	Neutral	0.191
NOTCH3	Q9UM47-1.2	L416F	Neutral	0.002
NOTCH3	Q9UM47-1.2	L416G	Neutral	0.458
NOTCH3	Q9UM47-1.2	L416H	Neutral	0.195
NOTCH3	Q9UM47-1.2	L416I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L416K	Neutral	0.05
NOTCH3	Q9UM47-1.2	L416M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L416N	Neutral	0.183
NOTCH3	Q9UM47-1.2	L416P	Neutral	0.178
NOTCH3	Q9UM47-1.2	L416Q	Neutral	0.05
NOTCH3	Q9UM47-1.2	L416R	Neutral	0.048
NOTCH3	Q9UM47-1.2	L416S	Neutral	0.043
NOTCH3	Q9UM47-1.2	L416T	Neutral	0.011
NOTCH3	Q9UM47-1.2	L416V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L416W	Neutral	0.045
NOTCH3	Q9UM47-1.2	L416Y	Neutral	0.011
NOTCH3	Q9UM47-1.2	C417A	Neutral	0.493
NOTCH3	Q9UM47-1.2	C417D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C417E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C417F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C417G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C417H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C417I	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C417K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C417L	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C417M	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C417N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C417P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C417Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C417R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C417S	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C417T	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C417V	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C417W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C417Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	Q418A	Neutral	0.206
NOTCH3	Q9UM47-1.2	Q418C	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	Q418D	Neutral	0.059
NOTCH3	Q9UM47-1.2	Q418E	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q418F	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	Q418G	Pathogenic	0.522
NOTCH3	Q9UM47-1.2	Q418H	Neutral	0.063
NOTCH3	Q9UM47-1.2	Q418I	Pathogenic	0.862
NOTCH3	Q9UM47-1.2	Q418K	Neutral	0.014
NOTCH3	Q9UM47-1.2	Q418L	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	Q418M	Neutral	0.062
NOTCH3	Q9UM47-1.2	Q418N	Neutral	0.06
NOTCH3	Q9UM47-1.2	Q418P	Neutral	0.221
NOTCH3	Q9UM47-1.2	Q418R	Neutral	0.013
NOTCH3	Q9UM47-1.2	Q418S	Neutral	0.055
NOTCH3	Q9UM47-1.2	Q418T	Neutral	0.222
NOTCH3	Q9UM47-1.2	Q418V	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	Q418W	Pathogenic	0.543
NOTCH3	Q9UM47-1.2	Q418Y	Neutral	0.219
NOTCH3	Q9UM47-1.2	C419A	Neutral	0.493
NOTCH3	Q9UM47-1.2	C419D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C419E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C419F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C419G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C419H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C419I	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C419K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C419L	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C419M	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C419N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C419P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C419Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C419R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C419S	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C419T	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C419V	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C419W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C419Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	G420A	Neutral	0.004
NOTCH3	Q9UM47-1.2	G420C	Neutral	0.259
NOTCH3	Q9UM47-1.2	G420D	Neutral	0.016
NOTCH3	Q9UM47-1.2	G420E	Neutral	0.066
NOTCH3	Q9UM47-1.2	G420F	Neutral	0.226
NOTCH3	Q9UM47-1.2	G420H	Neutral	0.063
NOTCH3	Q9UM47-1.2	G420I	Pathogenic	0.581
NOTCH3	Q9UM47-1.2	G420K	Neutral	0.06
NOTCH3	Q9UM47-1.2	G420L	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	G420M	Neutral	0.232
NOTCH3	Q9UM47-1.2	G420N	Neutral	0.004
NOTCH3	Q9UM47-1.2	G420P	Neutral	0.07
NOTCH3	Q9UM47-1.2	G420Q	Neutral	0.064
NOTCH3	Q9UM47-1.2	G420R	Neutral	0.057
NOTCH3	Q9UM47-1.2	G420S	Neutral	0.004
NOTCH3	Q9UM47-1.2	G420T	Neutral	0.069
NOTCH3	Q9UM47-1.2	G420V	Neutral	0.246
NOTCH3	Q9UM47-1.2	G420W	Neutral	0.055
NOTCH3	Q9UM47-1.2	G420Y	Neutral	0.22
NOTCH3	Q9UM47-1.2	R421A	Neutral	0.114
NOTCH3	Q9UM47-1.2	R421C	Pathogenic	0.743
NOTCH3	Q9UM47-1.2	R421D	Neutral	0.389
NOTCH3	Q9UM47-1.2	R421E	Neutral	0.032
NOTCH3	Q9UM47-1.2	R421F	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	R421G	Neutral	0.352
NOTCH3	Q9UM47-1.2	R421H	Neutral	0.033
NOTCH3	Q9UM47-1.2	R421I	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	R421K	Neutral	0.002
NOTCH3	Q9UM47-1.2	R421L	Neutral	0.425
NOTCH3	Q9UM47-1.2	R421M	Neutral	0.139
NOTCH3	Q9UM47-1.2	R421N	Neutral	0.03
NOTCH3	Q9UM47-1.2	R421P	Neutral	0.391
NOTCH3	Q9UM47-1.2	R421Q	Neutral	0.007
NOTCH3	Q9UM47-1.2	R421S	Neutral	0.116
NOTCH3	Q9UM47-1.2	R421T	Neutral	0.125
NOTCH3	Q9UM47-1.2	R421V	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	R421W	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	R421Y	Neutral	0.44
NOTCH3	Q9UM47-1.2	G422A	Neutral	0.232
NOTCH3	Q9UM47-1.2	G422C	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G422D	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	G422E	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	G422F	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G422H	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G422I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G422K	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G422L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G422M	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G422N	Neutral	0.213
NOTCH3	Q9UM47-1.2	G422P	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	G422Q	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	G422R	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	G422S	Neutral	0.227
NOTCH3	Q9UM47-1.2	G422T	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	G422V	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G422W	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	G422Y	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	Y423A	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	Y423C	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	Y423D	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	Y423E	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	Y423F	Neutral	0.022
NOTCH3	Q9UM47-1.2	Y423G	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	Y423H	Neutral	0.086
NOTCH3	Q9UM47-1.2	Y423I	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	Y423K	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	Y423L	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	Y423M	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	Y423N	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	Y423P	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	Y423Q	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	Y423R	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	Y423S	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	Y423T	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	Y423V	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	Y423W	Neutral	0.087
NOTCH3	Q9UM47-1.2	T424A	Neutral	0.063
NOTCH3	Q9UM47-1.2	T424C	Neutral	0.25
NOTCH3	Q9UM47-1.2	T424D	Neutral	0.254
NOTCH3	Q9UM47-1.2	T424E	Neutral	0.243
NOTCH3	Q9UM47-1.2	T424F	Pathogenic	0.571
NOTCH3	Q9UM47-1.2	T424G	Pathogenic	0.566
NOTCH3	Q9UM47-1.2	T424H	Pathogenic	0.584
NOTCH3	Q9UM47-1.2	T424I	Neutral	0.234
NOTCH3	Q9UM47-1.2	T424K	Neutral	0.226
NOTCH3	Q9UM47-1.2	T424L	Neutral	0.234
NOTCH3	Q9UM47-1.2	T424M	Neutral	0.233
NOTCH3	Q9UM47-1.2	T424N	Neutral	0.069
NOTCH3	Q9UM47-1.2	T424P	Neutral	0.252
NOTCH3	Q9UM47-1.2	T424Q	Neutral	0.239
NOTCH3	Q9UM47-1.2	T424R	Neutral	0.217
NOTCH3	Q9UM47-1.2	T424S	Neutral	0.015
NOTCH3	Q9UM47-1.2	T424V	Neutral	0.067
NOTCH3	Q9UM47-1.2	T424W	Pathogenic	0.545
NOTCH3	Q9UM47-1.2	T424Y	Pathogenic	0.564
NOTCH3	Q9UM47-1.2	G425A	Neutral	0.232
NOTCH3	Q9UM47-1.2	G425C	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G425D	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	G425E	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	G425F	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G425H	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G425I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G425K	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G425L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G425M	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G425N	Neutral	0.213
NOTCH3	Q9UM47-1.2	G425P	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	G425Q	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	G425R	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	G425S	Neutral	0.227
NOTCH3	Q9UM47-1.2	G425T	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	G425V	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G425W	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	G425Y	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	P426A	Pathogenic	0.637
NOTCH3	Q9UM47-1.2	P426C	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	P426D	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	P426E	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	P426F	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P426G	Pathogenic	0.882
NOTCH3	Q9UM47-1.2	P426H	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	P426I	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	P426K	Pathogenic	0.62
NOTCH3	Q9UM47-1.2	P426L	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	P426M	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	P426N	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	P426Q	Pathogenic	0.637
NOTCH3	Q9UM47-1.2	P426R	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	P426S	Pathogenic	0.643
NOTCH3	Q9UM47-1.2	P426T	Pathogenic	0.655
NOTCH3	Q9UM47-1.2	P426V	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	P426W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	P426Y	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	R427A	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	R427C	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R427D	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	R427E	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	R427F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R427G	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	R427H	Pathogenic	0.585
NOTCH3	Q9UM47-1.2	R427I	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R427K	Neutral	0.067
NOTCH3	Q9UM47-1.2	R427L	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	R427M	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	R427N	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	R427P	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	R427Q	Neutral	0.233
NOTCH3	Q9UM47-1.2	R427S	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	R427T	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	R427V	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R427W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R427Y	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	C428A	Neutral	0.493
NOTCH3	Q9UM47-1.2	C428D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C428E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C428F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C428G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C428H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C428I	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C428K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C428L	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C428M	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C428N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C428P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C428Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C428R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C428S	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C428T	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C428V	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C428W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C428Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	E429A	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	E429C	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	E429D	Neutral	0.044
NOTCH3	Q9UM47-1.2	E429F	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E429G	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	E429H	Neutral	0.499
NOTCH3	Q9UM47-1.2	E429I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E429K	Neutral	0.17
NOTCH3	Q9UM47-1.2	E429L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E429M	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	E429N	Neutral	0.494
NOTCH3	Q9UM47-1.2	E429P	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	E429Q	Neutral	0.046
NOTCH3	Q9UM47-1.2	E429R	Neutral	0.469
NOTCH3	Q9UM47-1.2	E429S	Neutral	0.473
NOTCH3	Q9UM47-1.2	E429T	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	E429V	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	E429W	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	E429Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	T430A	Neutral	0.01
NOTCH3	Q9UM47-1.2	T430C	Neutral	0.048
NOTCH3	Q9UM47-1.2	T430D	Neutral	0.049
NOTCH3	Q9UM47-1.2	T430E	Neutral	0.047
NOTCH3	Q9UM47-1.2	T430F	Neutral	0.168
NOTCH3	Q9UM47-1.2	T430G	Neutral	0.165
NOTCH3	Q9UM47-1.2	T430H	Neutral	0.176
NOTCH3	Q9UM47-1.2	T430I	Neutral	0.044
NOTCH3	Q9UM47-1.2	T430K	Neutral	0.042
NOTCH3	Q9UM47-1.2	T430L	Neutral	0.044
NOTCH3	Q9UM47-1.2	T430M	Neutral	0.044
NOTCH3	Q9UM47-1.2	T430N	Neutral	0.011
NOTCH3	Q9UM47-1.2	T430P	Neutral	0.049
NOTCH3	Q9UM47-1.2	T430Q	Neutral	0.046
NOTCH3	Q9UM47-1.2	T430R	Neutral	0.04
NOTCH3	Q9UM47-1.2	T430S	Neutral	0.002
NOTCH3	Q9UM47-1.2	T430V	Neutral	0.011
NOTCH3	Q9UM47-1.2	T430W	Neutral	0.154
NOTCH3	Q9UM47-1.2	T430Y	Neutral	0.164
NOTCH3	Q9UM47-1.2	D431A	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	D431C	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	D431E	Neutral	0.019
NOTCH3	Q9UM47-1.2	D431F	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	D431G	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	D431H	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	D431I	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	D431K	Pathogenic	0.626
NOTCH3	Q9UM47-1.2	D431L	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	D431M	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	D431N	Neutral	0.086
NOTCH3	Q9UM47-1.2	D431P	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	D431Q	Neutral	0.285
NOTCH3	Q9UM47-1.2	D431R	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	D431S	Neutral	0.289
NOTCH3	Q9UM47-1.2	D431T	Pathogenic	0.664
NOTCH3	Q9UM47-1.2	D431V	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	D431W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	D431Y	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	V432A	Neutral	0.141
NOTCH3	Q9UM47-1.2	V432C	Neutral	0.443
NOTCH3	Q9UM47-1.2	V432D	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	V432E	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	V432F	Neutral	0.434
NOTCH3	Q9UM47-1.2	V432G	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	V432H	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	V432I	Neutral	0.002
NOTCH3	Q9UM47-1.2	V432K	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	V432L	Neutral	0.037
NOTCH3	Q9UM47-1.2	V432M	Neutral	0.037
NOTCH3	Q9UM47-1.2	V432N	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	V432P	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	V432Q	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	V432R	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	V432S	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	V432T	Neutral	0.153
NOTCH3	Q9UM47-1.2	V432W	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	V432Y	Neutral	0.427
NOTCH3	Q9UM47-1.2	N433A	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	N433C	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	N433D	Neutral	0.147
NOTCH3	Q9UM47-1.2	N433E	Neutral	0.433
NOTCH3	Q9UM47-1.2	N433F	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N433G	Neutral	0.401
NOTCH3	Q9UM47-1.2	N433H	Neutral	0.14
NOTCH3	Q9UM47-1.2	N433I	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N433K	Neutral	0.409
NOTCH3	Q9UM47-1.2	N433L	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N433M	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	N433P	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	N433Q	Neutral	0.428
NOTCH3	Q9UM47-1.2	N433R	Neutral	0.397
NOTCH3	Q9UM47-1.2	N433S	Neutral	0.139
NOTCH3	Q9UM47-1.2	N433T	Neutral	0.444
NOTCH3	Q9UM47-1.2	N433V	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	N433W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N433Y	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	E434A	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	E434C	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	E434D	Neutral	0.045
NOTCH3	Q9UM47-1.2	E434F	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E434G	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	E434H	Pathogenic	0.503
NOTCH3	Q9UM47-1.2	E434I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	E434K	Neutral	0.172
NOTCH3	Q9UM47-1.2	E434L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	E434M	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	E434N	Neutral	0.497
NOTCH3	Q9UM47-1.2	E434P	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	E434Q	Neutral	0.047
NOTCH3	Q9UM47-1.2	E434R	Neutral	0.473
NOTCH3	Q9UM47-1.2	E434S	Neutral	0.476
NOTCH3	Q9UM47-1.2	E434T	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	E434V	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	E434W	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	E434Y	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	C435A	Neutral	0.493
NOTCH3	Q9UM47-1.2	C435D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C435E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C435F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C435G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C435H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C435I	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C435K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C435L	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C435M	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C435N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C435P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C435Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C435R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C435S	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C435T	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C435V	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C435W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C435Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	L436A	Neutral	0.036
NOTCH3	Q9UM47-1.2	L436C	Neutral	0.038
NOTCH3	Q9UM47-1.2	L436D	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	L436E	Neutral	0.478
NOTCH3	Q9UM47-1.2	L436F	Neutral	0.01
NOTCH3	Q9UM47-1.2	L436G	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	L436H	Neutral	0.485
NOTCH3	Q9UM47-1.2	L436I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L436K	Neutral	0.17
NOTCH3	Q9UM47-1.2	L436M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L436N	Neutral	0.465
NOTCH3	Q9UM47-1.2	L436P	Neutral	0.457
NOTCH3	Q9UM47-1.2	L436Q	Neutral	0.169
NOTCH3	Q9UM47-1.2	L436R	Neutral	0.163
NOTCH3	Q9UM47-1.2	L436S	Neutral	0.148
NOTCH3	Q9UM47-1.2	L436T	Neutral	0.04
NOTCH3	Q9UM47-1.2	L436V	Neutral	0.002
NOTCH3	Q9UM47-1.2	L436W	Neutral	0.153
NOTCH3	Q9UM47-1.2	L436Y	Neutral	0.041
NOTCH3	Q9UM47-1.2	S437A	Neutral	0.108
NOTCH3	Q9UM47-1.2	S437C	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	S437D	Neutral	0.345
NOTCH3	Q9UM47-1.2	S437E	Neutral	0.329
NOTCH3	Q9UM47-1.2	S437F	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	S437G	Neutral	0.337
NOTCH3	Q9UM47-1.2	S437H	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	S437I	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	S437K	Neutral	0.308
NOTCH3	Q9UM47-1.2	S437L	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	S437M	Pathogenic	0.679
NOTCH3	Q9UM47-1.2	S437N	Neutral	0.102
NOTCH3	Q9UM47-1.2	S437P	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	S437Q	Neutral	0.324
NOTCH3	Q9UM47-1.2	S437R	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	S437T	Neutral	0.103
NOTCH3	Q9UM47-1.2	S437V	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	S437W	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	S437Y	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	G438A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G438C	Neutral	0.133
NOTCH3	Q9UM47-1.2	G438D	Neutral	0.007
NOTCH3	Q9UM47-1.2	G438E	Neutral	0.03
NOTCH3	Q9UM47-1.2	G438F	Neutral	0.114
NOTCH3	Q9UM47-1.2	G438H	Neutral	0.029
NOTCH3	Q9UM47-1.2	G438I	Neutral	0.378
NOTCH3	Q9UM47-1.2	G438K	Neutral	0.027
NOTCH3	Q9UM47-1.2	G438L	Neutral	0.378
NOTCH3	Q9UM47-1.2	G438M	Neutral	0.117
NOTCH3	Q9UM47-1.2	G438N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G438P	Neutral	0.032
NOTCH3	Q9UM47-1.2	G438Q	Neutral	0.029
NOTCH3	Q9UM47-1.2	G438R	Neutral	0.026
NOTCH3	Q9UM47-1.2	G438S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G438T	Neutral	0.032
NOTCH3	Q9UM47-1.2	G438V	Neutral	0.125
NOTCH3	Q9UM47-1.2	G438W	Neutral	0.025
NOTCH3	Q9UM47-1.2	G438Y	Neutral	0.111
NOTCH3	Q9UM47-1.2	P439A	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	P439C	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	P439D	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	P439E	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	P439F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P439G	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	P439H	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	P439I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P439K	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	P439L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P439M	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	P439N	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	P439Q	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	P439R	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	P439S	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	P439T	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	P439V	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	P439W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P439Y	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	C440A	Neutral	0.493
NOTCH3	Q9UM47-1.2	C440D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C440E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C440F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C440G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C440H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C440I	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C440K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C440L	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C440M	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C440N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C440P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C440Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C440R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C440S	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C440T	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C440V	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C440W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C440Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	R441A	Neutral	0.062
NOTCH3	Q9UM47-1.2	R441C	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	R441D	Neutral	0.247
NOTCH3	Q9UM47-1.2	R441E	Neutral	0.017
NOTCH3	Q9UM47-1.2	R441F	Pathogenic	0.643
NOTCH3	Q9UM47-1.2	R441G	Neutral	0.218
NOTCH3	Q9UM47-1.2	R441H	Neutral	0.017
NOTCH3	Q9UM47-1.2	R441I	Pathogenic	0.633
NOTCH3	Q9UM47-1.2	R441K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R441L	Neutral	0.275
NOTCH3	Q9UM47-1.2	R441M	Neutral	0.077
NOTCH3	Q9UM47-1.2	R441N	Neutral	0.016
NOTCH3	Q9UM47-1.2	R441P	Neutral	0.248
NOTCH3	Q9UM47-1.2	R441Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	R441S	Neutral	0.063
NOTCH3	Q9UM47-1.2	R441T	Neutral	0.068
NOTCH3	Q9UM47-1.2	R441V	Pathogenic	0.615
NOTCH3	Q9UM47-1.2	R441W	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	R441Y	Neutral	0.287
NOTCH3	Q9UM47-1.2	N442A	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	N442C	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	N442D	Neutral	0.147
NOTCH3	Q9UM47-1.2	N442E	Neutral	0.433
NOTCH3	Q9UM47-1.2	N442F	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N442G	Neutral	0.401
NOTCH3	Q9UM47-1.2	N442H	Neutral	0.14
NOTCH3	Q9UM47-1.2	N442I	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N442K	Neutral	0.409
NOTCH3	Q9UM47-1.2	N442L	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N442M	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	N442P	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	N442Q	Neutral	0.428
NOTCH3	Q9UM47-1.2	N442R	Neutral	0.397
NOTCH3	Q9UM47-1.2	N442S	Neutral	0.139
NOTCH3	Q9UM47-1.2	N442T	Neutral	0.444
NOTCH3	Q9UM47-1.2	N442V	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	N442W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N442Y	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	Q443A	Neutral	0.066
NOTCH3	Q9UM47-1.2	Q443C	Pathogenic	0.614
NOTCH3	Q9UM47-1.2	Q443D	Neutral	0.017
NOTCH3	Q9UM47-1.2	Q443E	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q443F	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	Q443G	Neutral	0.23
NOTCH3	Q9UM47-1.2	Q443H	Neutral	0.018
NOTCH3	Q9UM47-1.2	Q443I	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	Q443K	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q443L	Neutral	0.273
NOTCH3	Q9UM47-1.2	Q443M	Neutral	0.018
NOTCH3	Q9UM47-1.2	Q443N	Neutral	0.017
NOTCH3	Q9UM47-1.2	Q443P	Neutral	0.072
NOTCH3	Q9UM47-1.2	Q443R	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q443S	Neutral	0.016
NOTCH3	Q9UM47-1.2	Q443T	Neutral	0.073
NOTCH3	Q9UM47-1.2	Q443V	Neutral	0.273
NOTCH3	Q9UM47-1.2	Q443W	Neutral	0.245
NOTCH3	Q9UM47-1.2	Q443Y	Neutral	0.071
NOTCH3	Q9UM47-1.2	A444C	Neutral	0.227
NOTCH3	Q9UM47-1.2	A444D	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	A444E	Pathogenic	0.551
NOTCH3	Q9UM47-1.2	A444F	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	A444G	Neutral	0.227
NOTCH3	Q9UM47-1.2	A444H	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	A444I	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	A444K	Pathogenic	0.527
NOTCH3	Q9UM47-1.2	A444L	Pathogenic	0.537
NOTCH3	Q9UM47-1.2	A444M	Pathogenic	0.536
NOTCH3	Q9UM47-1.2	A444N	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	A444P	Pathogenic	0.568
NOTCH3	Q9UM47-1.2	A444Q	Pathogenic	0.545
NOTCH3	Q9UM47-1.2	A444R	Pathogenic	0.514
NOTCH3	Q9UM47-1.2	A444S	Neutral	0.063
NOTCH3	Q9UM47-1.2	A444T	Neutral	0.221
NOTCH3	Q9UM47-1.2	A444V	Neutral	0.215
NOTCH3	Q9UM47-1.2	A444W	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	A444Y	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	T445A	Neutral	0.352
NOTCH3	Q9UM47-1.2	T445C	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	T445D	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	T445E	Pathogenic	0.721
NOTCH3	Q9UM47-1.2	T445F	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	T445G	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	T445H	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	T445I	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	T445K	Pathogenic	0.701
NOTCH3	Q9UM47-1.2	T445L	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	T445M	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	T445N	Neutral	0.374
NOTCH3	Q9UM47-1.2	T445P	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	T445Q	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	T445R	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	T445S	Neutral	0.109
NOTCH3	Q9UM47-1.2	T445V	Neutral	0.366
NOTCH3	Q9UM47-1.2	T445W	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	T445Y	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	C446A	Neutral	0.493
NOTCH3	Q9UM47-1.2	C446D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C446E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C446F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C446G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C446H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C446I	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C446K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C446L	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C446M	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C446N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C446P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C446Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C446R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C446S	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C446T	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C446V	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C446W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C446Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	L447A	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	L447C	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	L447D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L447E	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L447F	Neutral	0.365
NOTCH3	Q9UM47-1.2	L447G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L447H	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L447I	Neutral	0.028
NOTCH3	Q9UM47-1.2	L447K	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	L447M	Neutral	0.028
NOTCH3	Q9UM47-1.2	L447N	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L447P	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	L447Q	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	L447R	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	L447S	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	L447T	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	L447V	Neutral	0.109
NOTCH3	Q9UM47-1.2	L447W	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	L447Y	Pathogenic	0.72
NOTCH3	Q9UM47-1.2	D448A	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	D448C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D448E	Neutral	0.032
NOTCH3	Q9UM47-1.2	D448F	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D448G	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	D448H	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	D448I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D448K	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	D448L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D448M	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D448N	Neutral	0.135
NOTCH3	Q9UM47-1.2	D448P	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	D448Q	Neutral	0.399
NOTCH3	Q9UM47-1.2	D448R	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	D448S	Neutral	0.404
NOTCH3	Q9UM47-1.2	D448T	Pathogenic	0.767
NOTCH3	Q9UM47-1.2	D448V	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D448W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D448Y	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	R449A	Neutral	0.106
NOTCH3	Q9UM47-1.2	R449C	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	R449D	Neutral	0.371
NOTCH3	Q9UM47-1.2	R449E	Neutral	0.03
NOTCH3	Q9UM47-1.2	R449F	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	R449G	Neutral	0.334
NOTCH3	Q9UM47-1.2	R449H	Neutral	0.031
NOTCH3	Q9UM47-1.2	R449I	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	R449K	Neutral	0.002
NOTCH3	Q9UM47-1.2	R449L	Neutral	0.406
NOTCH3	Q9UM47-1.2	R449M	Neutral	0.13
NOTCH3	Q9UM47-1.2	R449N	Neutral	0.028
NOTCH3	Q9UM47-1.2	R449P	Neutral	0.372
NOTCH3	Q9UM47-1.2	R449Q	Neutral	0.007
NOTCH3	Q9UM47-1.2	R449S	Neutral	0.108
NOTCH3	Q9UM47-1.2	R449T	Neutral	0.116
NOTCH3	Q9UM47-1.2	R449V	Pathogenic	0.742
NOTCH3	Q9UM47-1.2	R449W	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	R449Y	Neutral	0.42
NOTCH3	Q9UM47-1.2	I450A	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	I450C	Pathogenic	0.867
NOTCH3	Q9UM47-1.2	I450D	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	I450E	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	I450F	Pathogenic	0.613
NOTCH3	Q9UM47-1.2	I450G	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	I450H	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	I450K	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	I450L	Neutral	0.074
NOTCH3	Q9UM47-1.2	I450M	Neutral	0.267
NOTCH3	Q9UM47-1.2	I450N	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	I450P	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	I450Q	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	I450R	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	I450S	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	I450T	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	I450V	Neutral	0.016
NOTCH3	Q9UM47-1.2	I450W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	I450Y	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	G451A	Neutral	0.229
NOTCH3	Q9UM47-1.2	G451C	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G451D	Pathogenic	0.552
NOTCH3	Q9UM47-1.2	G451E	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	G451F	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G451H	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	G451I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G451K	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	G451L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G451M	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G451N	Neutral	0.21
NOTCH3	Q9UM47-1.2	G451P	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	G451Q	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G451R	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	G451S	Neutral	0.224
NOTCH3	Q9UM47-1.2	G451T	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	G451V	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G451W	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	G451Y	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	Q452A	Neutral	0.027
NOTCH3	Q9UM47-1.2	Q452C	Neutral	0.383
NOTCH3	Q9UM47-1.2	Q452D	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q452E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q452F	Neutral	0.391
NOTCH3	Q9UM47-1.2	Q452G	Neutral	0.105
NOTCH3	Q9UM47-1.2	Q452H	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q452I	Neutral	0.401
NOTCH3	Q9UM47-1.2	Q452K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q452L	Neutral	0.128
NOTCH3	Q9UM47-1.2	Q452M	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q452N	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q452P	Neutral	0.029
NOTCH3	Q9UM47-1.2	Q452R	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q452S	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q452T	Neutral	0.03
NOTCH3	Q9UM47-1.2	Q452V	Neutral	0.128
NOTCH3	Q9UM47-1.2	Q452W	Neutral	0.113
NOTCH3	Q9UM47-1.2	Q452Y	Neutral	0.029
NOTCH3	Q9UM47-1.2	F453A	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	F453C	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	F453D	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	F453E	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	F453G	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	F453H	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	F453I	Pathogenic	0.702
NOTCH3	Q9UM47-1.2	F453K	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F453L	Pathogenic	0.702
NOTCH3	Q9UM47-1.2	F453M	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	F453N	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	F453P	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	F453Q	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	F453R	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F453S	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	F453T	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	F453V	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	F453W	Neutral	0.327
NOTCH3	Q9UM47-1.2	F453Y	Neutral	0.025
NOTCH3	Q9UM47-1.2	T454A	Neutral	0.059
NOTCH3	Q9UM47-1.2	T454C	Neutral	0.237
NOTCH3	Q9UM47-1.2	T454D	Neutral	0.241
NOTCH3	Q9UM47-1.2	T454E	Neutral	0.231
NOTCH3	Q9UM47-1.2	T454F	Pathogenic	0.555
NOTCH3	Q9UM47-1.2	T454G	Pathogenic	0.549
NOTCH3	Q9UM47-1.2	T454H	Pathogenic	0.568
NOTCH3	Q9UM47-1.2	T454I	Neutral	0.222
NOTCH3	Q9UM47-1.2	T454K	Neutral	0.215
NOTCH3	Q9UM47-1.2	T454L	Neutral	0.222
NOTCH3	Q9UM47-1.2	T454M	Neutral	0.221
NOTCH3	Q9UM47-1.2	T454N	Neutral	0.065
NOTCH3	Q9UM47-1.2	T454P	Neutral	0.24
NOTCH3	Q9UM47-1.2	T454Q	Neutral	0.227
NOTCH3	Q9UM47-1.2	T454R	Neutral	0.206
NOTCH3	Q9UM47-1.2	T454S	Neutral	0.014
NOTCH3	Q9UM47-1.2	T454V	Neutral	0.063
NOTCH3	Q9UM47-1.2	T454W	Pathogenic	0.529
NOTCH3	Q9UM47-1.2	T454Y	Pathogenic	0.547
NOTCH3	Q9UM47-1.2	C455A	Neutral	0.493
NOTCH3	Q9UM47-1.2	C455D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C455E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C455F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C455G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C455H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C455I	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C455K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C455L	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C455M	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C455N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C455P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C455Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C455R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C455S	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C455T	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C455V	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C455W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C455Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	I456A	Pathogenic	0.675
NOTCH3	Q9UM47-1.2	I456C	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	I456D	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	I456E	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	I456F	Neutral	0.35
NOTCH3	Q9UM47-1.2	I456G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I456H	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	I456K	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	I456L	Neutral	0.026
NOTCH3	Q9UM47-1.2	I456M	Neutral	0.11
NOTCH3	Q9UM47-1.2	I456N	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	I456P	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	I456Q	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	I456R	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	I456S	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	I456T	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	I456V	Neutral	0.006
NOTCH3	Q9UM47-1.2	I456W	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	I456Y	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	C457A	Neutral	0.493
NOTCH3	Q9UM47-1.2	C457D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C457E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C457F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C457G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C457H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C457I	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C457K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C457L	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C457M	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C457N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C457P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C457Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C457R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C457S	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C457T	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C457V	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C457W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C457Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	M458A	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	M458C	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	M458D	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	M458E	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	M458F	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	M458G	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	M458H	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	M458I	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	M458K	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	M458L	Neutral	0.298
NOTCH3	Q9UM47-1.2	M458N	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	M458P	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	M458Q	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	M458R	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	M458S	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	M458T	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	M458V	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	M458W	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	M458Y	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	A459C	Neutral	0.014
NOTCH3	Q9UM47-1.2	A459D	Neutral	0.228
NOTCH3	Q9UM47-1.2	A459E	Neutral	0.057
NOTCH3	Q9UM47-1.2	A459F	Neutral	0.2
NOTCH3	Q9UM47-1.2	A459G	Neutral	0.014
NOTCH3	Q9UM47-1.2	A459H	Neutral	0.209
NOTCH3	Q9UM47-1.2	A459I	Neutral	0.054
NOTCH3	Q9UM47-1.2	A459K	Neutral	0.052
NOTCH3	Q9UM47-1.2	A459L	Neutral	0.054
NOTCH3	Q9UM47-1.2	A459M	Neutral	0.054
NOTCH3	Q9UM47-1.2	A459N	Neutral	0.225
NOTCH3	Q9UM47-1.2	A459P	Neutral	0.061
NOTCH3	Q9UM47-1.2	A459Q	Neutral	0.056
NOTCH3	Q9UM47-1.2	A459R	Neutral	0.05
NOTCH3	Q9UM47-1.2	A459S	Neutral	0.003
NOTCH3	Q9UM47-1.2	A459T	Neutral	0.014
NOTCH3	Q9UM47-1.2	A459V	Neutral	0.013
NOTCH3	Q9UM47-1.2	A459W	Pathogenic	0.507
NOTCH3	Q9UM47-1.2	A459Y	Neutral	0.196
NOTCH3	Q9UM47-1.2	G460A	Neutral	0.231
NOTCH3	Q9UM47-1.2	G460C	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G460D	Pathogenic	0.556
NOTCH3	Q9UM47-1.2	G460E	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	G460F	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G460H	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	G460I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G460K	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	G460L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G460M	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G460N	Neutral	0.212
NOTCH3	Q9UM47-1.2	G460P	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	G460Q	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	G460R	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	G460S	Neutral	0.226
NOTCH3	Q9UM47-1.2	G460T	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	G460V	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G460W	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	G460Y	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	F461A	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	F461C	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	F461D	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	F461E	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	F461G	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	F461H	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	F461I	Neutral	0.368
NOTCH3	Q9UM47-1.2	F461K	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	F461L	Neutral	0.368
NOTCH3	Q9UM47-1.2	F461M	Neutral	0.369
NOTCH3	Q9UM47-1.2	F461N	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	F461P	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	F461Q	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	F461R	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	F461S	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	F461T	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	F461V	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	F461W	Neutral	0.107
NOTCH3	Q9UM47-1.2	F461Y	Neutral	0.006
NOTCH3	Q9UM47-1.2	T462A	Neutral	0.011
NOTCH3	Q9UM47-1.2	T462C	Neutral	0.052
NOTCH3	Q9UM47-1.2	T462D	Neutral	0.053
NOTCH3	Q9UM47-1.2	T462E	Neutral	0.05
NOTCH3	Q9UM47-1.2	T462F	Neutral	0.18
NOTCH3	Q9UM47-1.2	T462G	Neutral	0.177
NOTCH3	Q9UM47-1.2	T462H	Neutral	0.188
NOTCH3	Q9UM47-1.2	T462I	Neutral	0.048
NOTCH3	Q9UM47-1.2	T462K	Neutral	0.046
NOTCH3	Q9UM47-1.2	T462L	Neutral	0.048
NOTCH3	Q9UM47-1.2	T462M	Neutral	0.048
NOTCH3	Q9UM47-1.2	T462N	Neutral	0.012
NOTCH3	Q9UM47-1.2	T462P	Neutral	0.053
NOTCH3	Q9UM47-1.2	T462Q	Neutral	0.049
NOTCH3	Q9UM47-1.2	T462R	Neutral	0.044
NOTCH3	Q9UM47-1.2	T462S	Neutral	0.003
NOTCH3	Q9UM47-1.2	T462V	Neutral	0.012
NOTCH3	Q9UM47-1.2	T462W	Neutral	0.165
NOTCH3	Q9UM47-1.2	T462Y	Neutral	0.176
NOTCH3	Q9UM47-1.2	G463A	Neutral	0.231
NOTCH3	Q9UM47-1.2	G463C	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G463D	Pathogenic	0.556
NOTCH3	Q9UM47-1.2	G463E	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	G463F	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G463H	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	G463I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G463K	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	G463L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G463M	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G463N	Neutral	0.212
NOTCH3	Q9UM47-1.2	G463P	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	G463Q	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	G463R	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	G463S	Neutral	0.226
NOTCH3	Q9UM47-1.2	G463T	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	G463V	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G463W	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	G463Y	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	T464A	Neutral	0.023
NOTCH3	Q9UM47-1.2	T464C	Neutral	0.104
NOTCH3	Q9UM47-1.2	T464D	Neutral	0.106
NOTCH3	Q9UM47-1.2	T464E	Neutral	0.101
NOTCH3	Q9UM47-1.2	T464F	Neutral	0.318
NOTCH3	Q9UM47-1.2	T464G	Neutral	0.313
NOTCH3	Q9UM47-1.2	T464H	Neutral	0.33
NOTCH3	Q9UM47-1.2	T464I	Neutral	0.096
NOTCH3	Q9UM47-1.2	T464K	Neutral	0.093
NOTCH3	Q9UM47-1.2	T464L	Neutral	0.096
NOTCH3	Q9UM47-1.2	T464M	Neutral	0.096
NOTCH3	Q9UM47-1.2	T464N	Neutral	0.025
NOTCH3	Q9UM47-1.2	T464P	Neutral	0.105
NOTCH3	Q9UM47-1.2	T464Q	Neutral	0.099
NOTCH3	Q9UM47-1.2	T464R	Neutral	0.088
NOTCH3	Q9UM47-1.2	T464S	Neutral	0.005
NOTCH3	Q9UM47-1.2	T464V	Neutral	0.024
NOTCH3	Q9UM47-1.2	T464W	Neutral	0.296
NOTCH3	Q9UM47-1.2	T464Y	Neutral	0.311
NOTCH3	Q9UM47-1.2	Y465A	Pathogenic	0.647
NOTCH3	Q9UM47-1.2	Y465C	Pathogenic	0.662
NOTCH3	Q9UM47-1.2	Y465D	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	Y465E	Pathogenic	0.685
NOTCH3	Q9UM47-1.2	Y465F	Neutral	0.001
NOTCH3	Q9UM47-1.2	Y465G	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	Y465H	Neutral	0.005
NOTCH3	Q9UM47-1.2	Y465I	Neutral	0.334
NOTCH3	Q9UM47-1.2	Y465K	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	Y465L	Neutral	0.334
NOTCH3	Q9UM47-1.2	Y465M	Neutral	0.333
NOTCH3	Q9UM47-1.2	Y465N	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	Y465P	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	Y465Q	Neutral	0.326
NOTCH3	Q9UM47-1.2	Y465R	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	Y465S	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	Y465T	Pathogenic	0.67
NOTCH3	Q9UM47-1.2	Y465V	Neutral	0.317
NOTCH3	Q9UM47-1.2	Y465W	Neutral	0.005
NOTCH3	Q9UM47-1.2	C466A	Neutral	0.492
NOTCH3	Q9UM47-1.2	C466D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C466E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C466F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C466G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C466H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C466I	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C466K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C466L	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C466M	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C466N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C466P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C466Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C466R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C466S	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C466T	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C466V	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C466W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C466Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	E467A	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	E467C	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	E467D	Neutral	0.025
NOTCH3	Q9UM47-1.2	E467F	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	E467G	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	E467H	Neutral	0.355
NOTCH3	Q9UM47-1.2	E467I	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	E467K	Neutral	0.102
NOTCH3	Q9UM47-1.2	E467L	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	E467M	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	E467N	Neutral	0.351
NOTCH3	Q9UM47-1.2	E467P	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	E467Q	Neutral	0.026
NOTCH3	Q9UM47-1.2	E467R	Neutral	0.329
NOTCH3	Q9UM47-1.2	E467S	Neutral	0.332
NOTCH3	Q9UM47-1.2	E467T	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	E467V	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	E467W	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	E467Y	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	V468A	Neutral	0.025
NOTCH3	Q9UM47-1.2	V468C	Neutral	0.111
NOTCH3	Q9UM47-1.2	V468D	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	V468E	Neutral	0.38
NOTCH3	Q9UM47-1.2	V468F	Neutral	0.108
NOTCH3	Q9UM47-1.2	V468G	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	V468H	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	V468I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V468K	Neutral	0.357
NOTCH3	Q9UM47-1.2	V468L	Neutral	0.006
NOTCH3	Q9UM47-1.2	V468M	Neutral	0.006
NOTCH3	Q9UM47-1.2	V468N	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	V468P	Neutral	0.367
NOTCH3	Q9UM47-1.2	V468Q	Neutral	0.375
NOTCH3	Q9UM47-1.2	V468R	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	V468S	Neutral	0.354
NOTCH3	Q9UM47-1.2	V468T	Neutral	0.028
NOTCH3	Q9UM47-1.2	V468W	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	V468Y	Neutral	0.105
NOTCH3	Q9UM47-1.2	D469A	Neutral	0.455
NOTCH3	Q9UM47-1.2	D469C	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	D469E	Neutral	0.002
NOTCH3	Q9UM47-1.2	D469F	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	D469G	Neutral	0.145
NOTCH3	Q9UM47-1.2	D469H	Neutral	0.153
NOTCH3	Q9UM47-1.2	D469I	Pathogenic	0.788
NOTCH3	Q9UM47-1.2	D469K	Neutral	0.144
NOTCH3	Q9UM47-1.2	D469L	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	D469M	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	D469N	Neutral	0.009
NOTCH3	Q9UM47-1.2	D469P	Neutral	0.167
NOTCH3	Q9UM47-1.2	D469Q	Neutral	0.039
NOTCH3	Q9UM47-1.2	D469R	Neutral	0.422
NOTCH3	Q9UM47-1.2	D469S	Neutral	0.039
NOTCH3	Q9UM47-1.2	D469T	Neutral	0.166
NOTCH3	Q9UM47-1.2	D469V	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	D469W	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	D469Y	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	I470A	Neutral	0.471
NOTCH3	Q9UM47-1.2	I470C	Neutral	0.488
NOTCH3	Q9UM47-1.2	I470D	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	I470E	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	I470F	Neutral	0.188
NOTCH3	Q9UM47-1.2	I470G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	I470H	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	I470K	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	I470L	Neutral	0.012
NOTCH3	Q9UM47-1.2	I470M	Neutral	0.051
NOTCH3	Q9UM47-1.2	I470N	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	I470P	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	I470Q	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	I470R	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	I470S	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	I470T	Neutral	0.497
NOTCH3	Q9UM47-1.2	I470V	Neutral	0.002
NOTCH3	Q9UM47-1.2	I470W	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	I470Y	Pathogenic	0.509
NOTCH3	Q9UM47-1.2	D471A	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	D471C	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	D471E	Neutral	0.009
NOTCH3	Q9UM47-1.2	D471F	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	D471G	Neutral	0.428
NOTCH3	Q9UM47-1.2	D471H	Neutral	0.444
NOTCH3	Q9UM47-1.2	D471I	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	D471K	Neutral	0.426
NOTCH3	Q9UM47-1.2	D471L	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	D471M	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	D471N	Neutral	0.04
NOTCH3	Q9UM47-1.2	D471P	Neutral	0.47
NOTCH3	Q9UM47-1.2	D471Q	Neutral	0.151
NOTCH3	Q9UM47-1.2	D471R	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	D471S	Neutral	0.153
NOTCH3	Q9UM47-1.2	D471T	Neutral	0.468
NOTCH3	Q9UM47-1.2	D471V	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	D471W	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D471Y	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	E472A	Pathogenic	0.753
NOTCH3	Q9UM47-1.2	E472C	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	E472D	Neutral	0.034
NOTCH3	Q9UM47-1.2	E472F	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	E472G	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	E472H	Neutral	0.431
NOTCH3	Q9UM47-1.2	E472I	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	E472K	Neutral	0.134
NOTCH3	Q9UM47-1.2	E472L	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	E472M	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	E472N	Neutral	0.426
NOTCH3	Q9UM47-1.2	E472P	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	E472Q	Neutral	0.036
NOTCH3	Q9UM47-1.2	E472R	Neutral	0.402
NOTCH3	Q9UM47-1.2	E472S	Neutral	0.405
NOTCH3	Q9UM47-1.2	E472T	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	E472V	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	E472W	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	E472Y	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	C473A	Neutral	0.492
NOTCH3	Q9UM47-1.2	C473D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C473E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C473F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C473G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C473H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C473I	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C473K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C473L	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C473M	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C473N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C473P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C473Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C473R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C473S	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C473T	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C473V	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C473W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C473Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	Q474A	Neutral	0.135
NOTCH3	Q9UM47-1.2	Q474C	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	Q474D	Neutral	0.036
NOTCH3	Q9UM47-1.2	Q474E	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q474F	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	Q474G	Neutral	0.396
NOTCH3	Q9UM47-1.2	Q474H	Neutral	0.039
NOTCH3	Q9UM47-1.2	Q474I	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	Q474K	Neutral	0.008
NOTCH3	Q9UM47-1.2	Q474L	Neutral	0.452
NOTCH3	Q9UM47-1.2	Q474M	Neutral	0.038
NOTCH3	Q9UM47-1.2	Q474N	Neutral	0.037
NOTCH3	Q9UM47-1.2	Q474P	Neutral	0.146
NOTCH3	Q9UM47-1.2	Q474R	Neutral	0.008
NOTCH3	Q9UM47-1.2	Q474S	Neutral	0.034
NOTCH3	Q9UM47-1.2	Q474T	Neutral	0.147
NOTCH3	Q9UM47-1.2	Q474V	Neutral	0.452
NOTCH3	Q9UM47-1.2	Q474W	Neutral	0.416
NOTCH3	Q9UM47-1.2	Q474Y	Neutral	0.144
NOTCH3	Q9UM47-1.2	S475A	Neutral	0.057
NOTCH3	Q9UM47-1.2	S475C	Pathogenic	0.55
NOTCH3	Q9UM47-1.2	S475D	Neutral	0.208
NOTCH3	Q9UM47-1.2	S475E	Neutral	0.197
NOTCH3	Q9UM47-1.2	S475F	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	S475G	Neutral	0.203
NOTCH3	Q9UM47-1.2	S475H	Pathogenic	0.518
NOTCH3	Q9UM47-1.2	S475I	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	S475K	Neutral	0.182
NOTCH3	Q9UM47-1.2	S475L	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	S475M	Pathogenic	0.514
NOTCH3	Q9UM47-1.2	S475N	Neutral	0.054
NOTCH3	Q9UM47-1.2	S475P	Pathogenic	0.546
NOTCH3	Q9UM47-1.2	S475Q	Neutral	0.193
NOTCH3	Q9UM47-1.2	S475R	Neutral	0.491
NOTCH3	Q9UM47-1.2	S475T	Neutral	0.054
NOTCH3	Q9UM47-1.2	S475V	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	S475W	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	S475Y	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	S476A	Neutral	0.01
NOTCH3	Q9UM47-1.2	S476C	Neutral	0.176
NOTCH3	Q9UM47-1.2	S476D	Neutral	0.044
NOTCH3	Q9UM47-1.2	S476E	Neutral	0.041
NOTCH3	Q9UM47-1.2	S476F	Neutral	0.447
NOTCH3	Q9UM47-1.2	S476G	Neutral	0.042
NOTCH3	Q9UM47-1.2	S476H	Neutral	0.158
NOTCH3	Q9UM47-1.2	S476I	Neutral	0.457
NOTCH3	Q9UM47-1.2	S476K	Neutral	0.037
NOTCH3	Q9UM47-1.2	S476L	Neutral	0.457
NOTCH3	Q9UM47-1.2	S476M	Neutral	0.156
NOTCH3	Q9UM47-1.2	S476N	Neutral	0.01
NOTCH3	Q9UM47-1.2	S476P	Neutral	0.173
NOTCH3	Q9UM47-1.2	S476Q	Neutral	0.04
NOTCH3	Q9UM47-1.2	S476R	Neutral	0.144
NOTCH3	Q9UM47-1.2	S476T	Neutral	0.01
NOTCH3	Q9UM47-1.2	S476V	Neutral	0.474
NOTCH3	Q9UM47-1.2	S476W	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	S476Y	Neutral	0.44
NOTCH3	Q9UM47-1.2	P477A	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	P477C	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	P477D	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	P477E	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	P477F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P477G	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	P477H	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	P477I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P477K	Pathogenic	0.672
NOTCH3	Q9UM47-1.2	P477L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P477M	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	P477N	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	P477Q	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	P477R	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	P477S	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	P477T	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	P477V	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	P477W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P477Y	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	C478A	Neutral	0.492
NOTCH3	Q9UM47-1.2	C478D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C478E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C478F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C478G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C478H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C478I	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C478K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C478L	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C478M	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C478N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C478P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C478Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C478R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C478S	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C478T	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C478V	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C478W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C478Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	V479A	Neutral	0.114
NOTCH3	Q9UM47-1.2	V479C	Neutral	0.384
NOTCH3	Q9UM47-1.2	V479D	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	V479E	Pathogenic	0.753
NOTCH3	Q9UM47-1.2	V479F	Neutral	0.375
NOTCH3	Q9UM47-1.2	V479G	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	V479H	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	V479I	Neutral	0.001
NOTCH3	Q9UM47-1.2	V479K	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	V479L	Neutral	0.029
NOTCH3	Q9UM47-1.2	V479M	Neutral	0.029
NOTCH3	Q9UM47-1.2	V479N	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	V479P	Pathogenic	0.743
NOTCH3	Q9UM47-1.2	V479Q	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	V479R	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	V479S	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	V479T	Neutral	0.124
NOTCH3	Q9UM47-1.2	V479W	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	V479Y	Neutral	0.369
NOTCH3	Q9UM47-1.2	N480A	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	N480C	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	N480D	Neutral	0.046
NOTCH3	Q9UM47-1.2	N480E	Neutral	0.175
NOTCH3	Q9UM47-1.2	N480F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	N480G	Neutral	0.157
NOTCH3	Q9UM47-1.2	N480H	Neutral	0.043
NOTCH3	Q9UM47-1.2	N480I	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	N480K	Neutral	0.161
NOTCH3	Q9UM47-1.2	N480L	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	N480M	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	N480P	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	N480Q	Neutral	0.172
NOTCH3	Q9UM47-1.2	N480R	Neutral	0.155
NOTCH3	Q9UM47-1.2	N480S	Neutral	0.043
NOTCH3	Q9UM47-1.2	N480T	Neutral	0.181
NOTCH3	Q9UM47-1.2	N480V	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	N480W	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	N480Y	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	G481A	Neutral	0.005
NOTCH3	Q9UM47-1.2	G481C	Neutral	0.321
NOTCH3	Q9UM47-1.2	G481D	Neutral	0.022
NOTCH3	Q9UM47-1.2	G481E	Neutral	0.086
NOTCH3	Q9UM47-1.2	G481F	Neutral	0.282
NOTCH3	Q9UM47-1.2	G481H	Neutral	0.083
NOTCH3	Q9UM47-1.2	G481I	Pathogenic	0.651
NOTCH3	Q9UM47-1.2	G481K	Neutral	0.079
NOTCH3	Q9UM47-1.2	G481L	Pathogenic	0.651
NOTCH3	Q9UM47-1.2	G481M	Neutral	0.29
NOTCH3	Q9UM47-1.2	G481N	Neutral	0.005
NOTCH3	Q9UM47-1.2	G481P	Neutral	0.092
NOTCH3	Q9UM47-1.2	G481Q	Neutral	0.085
NOTCH3	Q9UM47-1.2	G481R	Neutral	0.075
NOTCH3	Q9UM47-1.2	G481S	Neutral	0.005
NOTCH3	Q9UM47-1.2	G481T	Neutral	0.091
NOTCH3	Q9UM47-1.2	G481V	Neutral	0.305
NOTCH3	Q9UM47-1.2	G481W	Neutral	0.072
NOTCH3	Q9UM47-1.2	G481Y	Neutral	0.276
NOTCH3	Q9UM47-1.2	G482A	Neutral	0.213
NOTCH3	Q9UM47-1.2	G482C	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G482D	Pathogenic	0.53
NOTCH3	Q9UM47-1.2	G482E	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	G482F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	G482H	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	G482I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G482K	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	G482L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G482M	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G482N	Neutral	0.195
NOTCH3	Q9UM47-1.2	G482P	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G482Q	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G482R	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	G482S	Neutral	0.209
NOTCH3	Q9UM47-1.2	G482T	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G482V	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G482W	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	G482Y	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	V483A	Neutral	0.007
NOTCH3	Q9UM47-1.2	V483C	Neutral	0.032
NOTCH3	Q9UM47-1.2	V483D	Neutral	0.412
NOTCH3	Q9UM47-1.2	V483E	Neutral	0.138
NOTCH3	Q9UM47-1.2	V483F	Neutral	0.031
NOTCH3	Q9UM47-1.2	V483G	Neutral	0.371
NOTCH3	Q9UM47-1.2	V483H	Neutral	0.411
NOTCH3	Q9UM47-1.2	V483I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V483K	Neutral	0.127
NOTCH3	Q9UM47-1.2	V483L	Neutral	0.002
NOTCH3	Q9UM47-1.2	V483M	Neutral	0.002
NOTCH3	Q9UM47-1.2	V483N	Neutral	0.417
NOTCH3	Q9UM47-1.2	V483P	Neutral	0.132
NOTCH3	Q9UM47-1.2	V483Q	Neutral	0.135
NOTCH3	Q9UM47-1.2	V483R	Neutral	0.386
NOTCH3	Q9UM47-1.2	V483S	Neutral	0.125
NOTCH3	Q9UM47-1.2	V483T	Neutral	0.007
NOTCH3	Q9UM47-1.2	V483W	Neutral	0.37
NOTCH3	Q9UM47-1.2	V483Y	Neutral	0.03
NOTCH3	Q9UM47-1.2	C484A	Neutral	0.487
NOTCH3	Q9UM47-1.2	C484D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C484E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C484F	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	C484G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C484H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C484I	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	C484K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C484L	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	C484M	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	C484N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C484P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C484Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C484R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C484S	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C484T	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C484V	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	C484W	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	C484Y	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	K485A	Neutral	0.057
NOTCH3	Q9UM47-1.2	K485C	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	K485D	Neutral	0.061
NOTCH3	Q9UM47-1.2	K485E	Neutral	0.003
NOTCH3	Q9UM47-1.2	K485F	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	K485G	Neutral	0.203
NOTCH3	Q9UM47-1.2	K485H	Neutral	0.068
NOTCH3	Q9UM47-1.2	K485I	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	K485L	Neutral	0.257
NOTCH3	Q9UM47-1.2	K485M	Neutral	0.07
NOTCH3	Q9UM47-1.2	K485N	Neutral	0.014
NOTCH3	Q9UM47-1.2	K485P	Neutral	0.062
NOTCH3	Q9UM47-1.2	K485Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	K485R	Neutral	0.001
NOTCH3	Q9UM47-1.2	K485S	Neutral	0.013
NOTCH3	Q9UM47-1.2	K485T	Neutral	0.062
NOTCH3	Q9UM47-1.2	K485V	Neutral	0.242
NOTCH3	Q9UM47-1.2	K485W	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	K485Y	Neutral	0.259
NOTCH3	Q9UM47-1.2	D486A	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	D486C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D486E	Neutral	0.032
NOTCH3	Q9UM47-1.2	D486F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D486G	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	D486H	Pathogenic	0.753
NOTCH3	Q9UM47-1.2	D486I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D486K	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	D486L	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	D486M	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D486N	Neutral	0.137
NOTCH3	Q9UM47-1.2	D486P	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	D486Q	Neutral	0.404
NOTCH3	Q9UM47-1.2	D486R	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	D486S	Neutral	0.409
NOTCH3	Q9UM47-1.2	D486T	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	D486V	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D486W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D486Y	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	R487A	Neutral	0.048
NOTCH3	Q9UM47-1.2	R487C	Pathogenic	0.53
NOTCH3	Q9UM47-1.2	R487D	Neutral	0.199
NOTCH3	Q9UM47-1.2	R487E	Neutral	0.013
NOTCH3	Q9UM47-1.2	R487F	Pathogenic	0.578
NOTCH3	Q9UM47-1.2	R487G	Neutral	0.175
NOTCH3	Q9UM47-1.2	R487H	Neutral	0.013
NOTCH3	Q9UM47-1.2	R487I	Pathogenic	0.568
NOTCH3	Q9UM47-1.2	R487K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R487L	Neutral	0.224
NOTCH3	Q9UM47-1.2	R487M	Neutral	0.059
NOTCH3	Q9UM47-1.2	R487N	Neutral	0.012
NOTCH3	Q9UM47-1.2	R487P	Neutral	0.2
NOTCH3	Q9UM47-1.2	R487Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R487S	Neutral	0.049
NOTCH3	Q9UM47-1.2	R487T	Neutral	0.053
NOTCH3	Q9UM47-1.2	R487V	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	R487W	Pathogenic	0.577
NOTCH3	Q9UM47-1.2	R487Y	Neutral	0.234
NOTCH3	Q9UM47-1.2	V488A	Neutral	0.159
NOTCH3	Q9UM47-1.2	V488C	Neutral	0.48
NOTCH3	Q9UM47-1.2	V488D	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	V488E	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	V488F	Neutral	0.47
NOTCH3	Q9UM47-1.2	V488G	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	V488H	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	V488I	Neutral	0.002
NOTCH3	Q9UM47-1.2	V488K	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	V488L	Neutral	0.043
NOTCH3	Q9UM47-1.2	V488M	Neutral	0.043
NOTCH3	Q9UM47-1.2	V488N	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	V488P	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	V488Q	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	V488R	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	V488S	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	V488T	Neutral	0.173
NOTCH3	Q9UM47-1.2	V488W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	V488Y	Neutral	0.464
NOTCH3	Q9UM47-1.2	N489A	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	N489C	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	N489D	Neutral	0.083
NOTCH3	Q9UM47-1.2	N489E	Neutral	0.286
NOTCH3	Q9UM47-1.2	N489F	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	N489G	Neutral	0.26
NOTCH3	Q9UM47-1.2	N489H	Neutral	0.079
NOTCH3	Q9UM47-1.2	N489I	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	N489K	Neutral	0.267
NOTCH3	Q9UM47-1.2	N489L	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	N489M	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	N489P	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	N489Q	Neutral	0.283
NOTCH3	Q9UM47-1.2	N489R	Neutral	0.257
NOTCH3	Q9UM47-1.2	N489S	Neutral	0.078
NOTCH3	Q9UM47-1.2	N489T	Neutral	0.295
NOTCH3	Q9UM47-1.2	N489V	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	N489W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	N489Y	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	G490A	Neutral	0.004
NOTCH3	Q9UM47-1.2	G490C	Neutral	0.252
NOTCH3	Q9UM47-1.2	G490D	Neutral	0.016
NOTCH3	Q9UM47-1.2	G490E	Neutral	0.063
NOTCH3	Q9UM47-1.2	G490F	Neutral	0.219
NOTCH3	Q9UM47-1.2	G490H	Neutral	0.061
NOTCH3	Q9UM47-1.2	G490I	Pathogenic	0.571
NOTCH3	Q9UM47-1.2	G490K	Neutral	0.058
NOTCH3	Q9UM47-1.2	G490L	Pathogenic	0.571
NOTCH3	Q9UM47-1.2	G490M	Neutral	0.226
NOTCH3	Q9UM47-1.2	G490N	Neutral	0.003
NOTCH3	Q9UM47-1.2	G490P	Neutral	0.068
NOTCH3	Q9UM47-1.2	G490Q	Neutral	0.062
NOTCH3	Q9UM47-1.2	G490R	Neutral	0.055
NOTCH3	Q9UM47-1.2	G490S	Neutral	0.004
NOTCH3	Q9UM47-1.2	G490T	Neutral	0.067
NOTCH3	Q9UM47-1.2	G490V	Neutral	0.239
NOTCH3	Q9UM47-1.2	G490W	Neutral	0.053
NOTCH3	Q9UM47-1.2	G490Y	Neutral	0.214
NOTCH3	Q9UM47-1.2	F491A	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	F491C	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	F491D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F491E	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F491G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	F491H	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	F491I	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	F491K	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F491L	Pathogenic	0.747
NOTCH3	Q9UM47-1.2	F491M	Pathogenic	0.747
NOTCH3	Q9UM47-1.2	F491N	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F491P	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	F491Q	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F491R	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F491S	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	F491T	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	F491V	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	F491W	Neutral	0.378
NOTCH3	Q9UM47-1.2	F491Y	Neutral	0.031
NOTCH3	Q9UM47-1.2	S492A	Neutral	0.0
NOTCH3	Q9UM47-1.2	S492C	Neutral	0.008
NOTCH3	Q9UM47-1.2	S492D	Neutral	0.002
NOTCH3	Q9UM47-1.2	S492E	Neutral	0.002
NOTCH3	Q9UM47-1.2	S492F	Neutral	0.029
NOTCH3	Q9UM47-1.2	S492G	Neutral	0.002
NOTCH3	Q9UM47-1.2	S492H	Neutral	0.007
NOTCH3	Q9UM47-1.2	S492I	Neutral	0.031
NOTCH3	Q9UM47-1.2	S492K	Neutral	0.001
NOTCH3	Q9UM47-1.2	S492L	Neutral	0.031
NOTCH3	Q9UM47-1.2	S492M	Neutral	0.007
NOTCH3	Q9UM47-1.2	S492N	Neutral	0.0
NOTCH3	Q9UM47-1.2	S492P	Neutral	0.008
NOTCH3	Q9UM47-1.2	S492Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	S492R	Neutral	0.006
NOTCH3	Q9UM47-1.2	S492T	Neutral	0.0
NOTCH3	Q9UM47-1.2	S492V	Neutral	0.033
NOTCH3	Q9UM47-1.2	S492W	Neutral	0.11
NOTCH3	Q9UM47-1.2	S492Y	Neutral	0.028
NOTCH3	Q9UM47-1.2	C493A	Neutral	0.492
NOTCH3	Q9UM47-1.2	C493D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C493E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C493F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C493G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C493H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C493I	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C493K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C493L	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C493M	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C493N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C493P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C493Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C493R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C493S	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C493T	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C493V	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C493W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C493Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	T494A	Neutral	0.008
NOTCH3	Q9UM47-1.2	T494C	Neutral	0.037
NOTCH3	Q9UM47-1.2	T494D	Neutral	0.038
NOTCH3	Q9UM47-1.2	T494E	Neutral	0.036
NOTCH3	Q9UM47-1.2	T494F	Neutral	0.133
NOTCH3	Q9UM47-1.2	T494G	Neutral	0.13
NOTCH3	Q9UM47-1.2	T494H	Neutral	0.139
NOTCH3	Q9UM47-1.2	T494I	Neutral	0.034
NOTCH3	Q9UM47-1.2	T494K	Neutral	0.033
NOTCH3	Q9UM47-1.2	T494L	Neutral	0.034
NOTCH3	Q9UM47-1.2	T494M	Neutral	0.034
NOTCH3	Q9UM47-1.2	T494N	Neutral	0.008
NOTCH3	Q9UM47-1.2	T494P	Neutral	0.037
NOTCH3	Q9UM47-1.2	T494Q	Neutral	0.035
NOTCH3	Q9UM47-1.2	T494R	Neutral	0.031
NOTCH3	Q9UM47-1.2	T494S	Neutral	0.002
NOTCH3	Q9UM47-1.2	T494V	Neutral	0.008
NOTCH3	Q9UM47-1.2	T494W	Neutral	0.121
NOTCH3	Q9UM47-1.2	T494Y	Neutral	0.13
NOTCH3	Q9UM47-1.2	C495A	Neutral	0.492
NOTCH3	Q9UM47-1.2	C495D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C495E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C495F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C495G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C495H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C495I	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C495K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C495L	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C495M	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C495N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C495P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C495Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C495R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C495S	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C495T	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C495V	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C495W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C495Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	P496A	Neutral	0.439
NOTCH3	Q9UM47-1.2	P496C	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	P496D	Neutral	0.462
NOTCH3	Q9UM47-1.2	P496E	Neutral	0.445
NOTCH3	Q9UM47-1.2	P496F	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	P496G	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	P496H	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	P496I	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	P496K	Neutral	0.421
NOTCH3	Q9UM47-1.2	P496L	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	P496M	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	P496N	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	P496Q	Neutral	0.439
NOTCH3	Q9UM47-1.2	P496R	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	P496S	Neutral	0.445
NOTCH3	Q9UM47-1.2	P496T	Neutral	0.458
NOTCH3	Q9UM47-1.2	P496V	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	P496W	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	P496Y	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	S497A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S497C	Neutral	0.013
NOTCH3	Q9UM47-1.2	S497D	Neutral	0.003
NOTCH3	Q9UM47-1.2	S497E	Neutral	0.003
NOTCH3	Q9UM47-1.2	S497F	Neutral	0.049
NOTCH3	Q9UM47-1.2	S497G	Neutral	0.003
NOTCH3	Q9UM47-1.2	S497H	Neutral	0.012
NOTCH3	Q9UM47-1.2	S497I	Neutral	0.051
NOTCH3	Q9UM47-1.2	S497K	Neutral	0.002
NOTCH3	Q9UM47-1.2	S497L	Neutral	0.051
NOTCH3	Q9UM47-1.2	S497M	Neutral	0.012
NOTCH3	Q9UM47-1.2	S497N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S497P	Neutral	0.013
NOTCH3	Q9UM47-1.2	S497Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	S497R	Neutral	0.011
NOTCH3	Q9UM47-1.2	S497T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S497V	Neutral	0.054
NOTCH3	Q9UM47-1.2	S497W	Neutral	0.174
NOTCH3	Q9UM47-1.2	S497Y	Neutral	0.047
NOTCH3	Q9UM47-1.2	G498A	Neutral	0.239
NOTCH3	Q9UM47-1.2	G498C	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	G498D	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	G498E	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	G498F	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G498H	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	G498I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G498K	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	G498L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G498M	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G498N	Neutral	0.22
NOTCH3	Q9UM47-1.2	G498P	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	G498Q	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	G498R	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	G498S	Neutral	0.235
NOTCH3	Q9UM47-1.2	G498T	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	G498V	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G498W	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	G498Y	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	F499A	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	F499C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	F499D	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F499E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F499G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F499H	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	F499I	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	F499K	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F499L	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	F499M	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	F499N	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F499P	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	F499Q	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F499R	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F499S	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	F499T	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	F499V	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	F499W	Neutral	0.427
NOTCH3	Q9UM47-1.2	F499Y	Neutral	0.038
NOTCH3	Q9UM47-1.2	S500A	Neutral	0.008
NOTCH3	Q9UM47-1.2	S500C	Neutral	0.133
NOTCH3	Q9UM47-1.2	S500D	Neutral	0.032
NOTCH3	Q9UM47-1.2	S500E	Neutral	0.03
NOTCH3	Q9UM47-1.2	S500F	Neutral	0.369
NOTCH3	Q9UM47-1.2	S500G	Neutral	0.031
NOTCH3	Q9UM47-1.2	S500H	Neutral	0.119
NOTCH3	Q9UM47-1.2	S500I	Neutral	0.379
NOTCH3	Q9UM47-1.2	S500K	Neutral	0.027
NOTCH3	Q9UM47-1.2	S500L	Neutral	0.378
NOTCH3	Q9UM47-1.2	S500M	Neutral	0.118
NOTCH3	Q9UM47-1.2	S500N	Neutral	0.007
NOTCH3	Q9UM47-1.2	S500P	Neutral	0.131
NOTCH3	Q9UM47-1.2	S500Q	Neutral	0.029
NOTCH3	Q9UM47-1.2	S500R	Neutral	0.108
NOTCH3	Q9UM47-1.2	S500T	Neutral	0.007
NOTCH3	Q9UM47-1.2	S500V	Neutral	0.395
NOTCH3	Q9UM47-1.2	S500W	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	S500Y	Neutral	0.362
NOTCH3	Q9UM47-1.2	G501A	Neutral	0.227
NOTCH3	Q9UM47-1.2	G501C	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G501D	Pathogenic	0.551
NOTCH3	Q9UM47-1.2	G501E	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	G501F	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G501H	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	G501I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G501K	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	G501L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G501M	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G501N	Neutral	0.209
NOTCH3	Q9UM47-1.2	G501P	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G501Q	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	G501R	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	G501S	Neutral	0.223
NOTCH3	Q9UM47-1.2	G501T	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G501V	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G501W	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	G501Y	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	S502A	Neutral	0.0
NOTCH3	Q9UM47-1.2	S502C	Neutral	0.01
NOTCH3	Q9UM47-1.2	S502D	Neutral	0.002
NOTCH3	Q9UM47-1.2	S502E	Neutral	0.002
NOTCH3	Q9UM47-1.2	S502F	Neutral	0.037
NOTCH3	Q9UM47-1.2	S502G	Neutral	0.002
NOTCH3	Q9UM47-1.2	S502H	Neutral	0.009
NOTCH3	Q9UM47-1.2	S502I	Neutral	0.038
NOTCH3	Q9UM47-1.2	S502K	Neutral	0.002
NOTCH3	Q9UM47-1.2	S502L	Neutral	0.038
NOTCH3	Q9UM47-1.2	S502M	Neutral	0.009
NOTCH3	Q9UM47-1.2	S502N	Neutral	0.0
NOTCH3	Q9UM47-1.2	S502P	Neutral	0.01
NOTCH3	Q9UM47-1.2	S502Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	S502R	Neutral	0.008
NOTCH3	Q9UM47-1.2	S502T	Neutral	0.0
NOTCH3	Q9UM47-1.2	S502V	Neutral	0.041
NOTCH3	Q9UM47-1.2	S502W	Neutral	0.135
NOTCH3	Q9UM47-1.2	S502Y	Neutral	0.036
NOTCH3	Q9UM47-1.2	T503A	Neutral	0.002
NOTCH3	Q9UM47-1.2	T503C	Neutral	0.011
NOTCH3	Q9UM47-1.2	T503D	Neutral	0.011
NOTCH3	Q9UM47-1.2	T503E	Neutral	0.011
NOTCH3	Q9UM47-1.2	T503F	Neutral	0.042
NOTCH3	Q9UM47-1.2	T503G	Neutral	0.041
NOTCH3	Q9UM47-1.2	T503H	Neutral	0.044
NOTCH3	Q9UM47-1.2	T503I	Neutral	0.01
NOTCH3	Q9UM47-1.2	T503K	Neutral	0.01
NOTCH3	Q9UM47-1.2	T503L	Neutral	0.01
NOTCH3	Q9UM47-1.2	T503M	Neutral	0.01
NOTCH3	Q9UM47-1.2	T503N	Neutral	0.002
NOTCH3	Q9UM47-1.2	T503P	Neutral	0.011
NOTCH3	Q9UM47-1.2	T503Q	Neutral	0.01
NOTCH3	Q9UM47-1.2	T503R	Neutral	0.009
NOTCH3	Q9UM47-1.2	T503S	Neutral	0.001
NOTCH3	Q9UM47-1.2	T503V	Neutral	0.002
NOTCH3	Q9UM47-1.2	T503W	Neutral	0.038
NOTCH3	Q9UM47-1.2	T503Y	Neutral	0.041
NOTCH3	Q9UM47-1.2	C504A	Neutral	0.49
NOTCH3	Q9UM47-1.2	C504D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C504E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C504F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C504G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C504H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C504I	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C504K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C504L	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C504M	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C504N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C504P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C504Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C504R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C504S	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C504T	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	C504V	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C504W	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	C504Y	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	Q505A	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	Q505C	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	Q505D	Neutral	0.469
NOTCH3	Q9UM47-1.2	Q505E	Neutral	0.044
NOTCH3	Q9UM47-1.2	Q505F	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	Q505G	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	Q505H	Neutral	0.487
NOTCH3	Q9UM47-1.2	Q505I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	Q505K	Neutral	0.164
NOTCH3	Q9UM47-1.2	Q505L	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	Q505M	Neutral	0.483
NOTCH3	Q9UM47-1.2	Q505N	Neutral	0.473
NOTCH3	Q9UM47-1.2	Q505P	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	Q505R	Neutral	0.157
NOTCH3	Q9UM47-1.2	Q505S	Neutral	0.451
NOTCH3	Q9UM47-1.2	Q505T	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	Q505V	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	Q505W	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	Q505Y	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	L506A	Neutral	0.016
NOTCH3	Q9UM47-1.2	L506C	Neutral	0.017
NOTCH3	Q9UM47-1.2	L506D	Pathogenic	0.626
NOTCH3	Q9UM47-1.2	L506E	Neutral	0.283
NOTCH3	Q9UM47-1.2	L506F	Neutral	0.004
NOTCH3	Q9UM47-1.2	L506G	Pathogenic	0.585
NOTCH3	Q9UM47-1.2	L506H	Neutral	0.288
NOTCH3	Q9UM47-1.2	L506I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L506K	Neutral	0.081
NOTCH3	Q9UM47-1.2	L506M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L506N	Neutral	0.273
NOTCH3	Q9UM47-1.2	L506P	Neutral	0.266
NOTCH3	Q9UM47-1.2	L506Q	Neutral	0.081
NOTCH3	Q9UM47-1.2	L506R	Neutral	0.077
NOTCH3	Q9UM47-1.2	L506S	Neutral	0.07
NOTCH3	Q9UM47-1.2	L506T	Neutral	0.017
NOTCH3	Q9UM47-1.2	L506V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L506W	Neutral	0.072
NOTCH3	Q9UM47-1.2	L506Y	Neutral	0.018
NOTCH3	Q9UM47-1.2	D507A	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	D507C	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	D507E	Neutral	0.018
NOTCH3	Q9UM47-1.2	D507F	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	D507G	Pathogenic	0.616
NOTCH3	Q9UM47-1.2	D507H	Pathogenic	0.631
NOTCH3	Q9UM47-1.2	D507I	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	D507K	Pathogenic	0.614
NOTCH3	Q9UM47-1.2	D507L	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	D507M	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	D507N	Neutral	0.082
NOTCH3	Q9UM47-1.2	D507P	Pathogenic	0.655
NOTCH3	Q9UM47-1.2	D507Q	Neutral	0.276
NOTCH3	Q9UM47-1.2	D507R	Pathogenic	0.873
NOTCH3	Q9UM47-1.2	D507S	Neutral	0.28
NOTCH3	Q9UM47-1.2	D507T	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	D507V	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	D507W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	D507Y	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	V508A	Neutral	0.064
NOTCH3	Q9UM47-1.2	V508C	Neutral	0.25
NOTCH3	Q9UM47-1.2	V508D	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	V508E	Pathogenic	0.62
NOTCH3	Q9UM47-1.2	V508F	Neutral	0.243
NOTCH3	Q9UM47-1.2	V508G	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	V508H	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	V508I	Neutral	0.001
NOTCH3	Q9UM47-1.2	V508K	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	V508L	Neutral	0.016
NOTCH3	Q9UM47-1.2	V508M	Neutral	0.016
NOTCH3	Q9UM47-1.2	V508N	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	V508P	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	V508Q	Pathogenic	0.615
NOTCH3	Q9UM47-1.2	V508R	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	V508S	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	V508T	Neutral	0.07
NOTCH3	Q9UM47-1.2	V508W	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	V508Y	Neutral	0.238
NOTCH3	Q9UM47-1.2	D509A	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	D509C	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D509E	Neutral	0.03
NOTCH3	Q9UM47-1.2	D509F	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D509G	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	D509H	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	D509I	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D509K	Pathogenic	0.722
NOTCH3	Q9UM47-1.2	D509L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D509M	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D509N	Neutral	0.127
NOTCH3	Q9UM47-1.2	D509P	Pathogenic	0.756
NOTCH3	Q9UM47-1.2	D509Q	Neutral	0.383
NOTCH3	Q9UM47-1.2	D509R	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	D509S	Neutral	0.388
NOTCH3	Q9UM47-1.2	D509T	Pathogenic	0.755
NOTCH3	Q9UM47-1.2	D509V	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D509W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D509Y	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	E510A	Neutral	0.498
NOTCH3	Q9UM47-1.2	E510C	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	E510D	Neutral	0.011
NOTCH3	Q9UM47-1.2	E510F	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	E510G	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	E510H	Neutral	0.198
NOTCH3	Q9UM47-1.2	E510I	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	E510K	Neutral	0.048
NOTCH3	Q9UM47-1.2	E510L	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	E510M	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	E510N	Neutral	0.195
NOTCH3	Q9UM47-1.2	E510P	Pathogenic	0.521
NOTCH3	Q9UM47-1.2	E510Q	Neutral	0.012
NOTCH3	Q9UM47-1.2	E510R	Neutral	0.18
NOTCH3	Q9UM47-1.2	E510S	Neutral	0.182
NOTCH3	Q9UM47-1.2	E510T	Pathogenic	0.523
NOTCH3	Q9UM47-1.2	E510V	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	E510W	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	E510Y	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C511A	Pathogenic	0.503
NOTCH3	Q9UM47-1.2	C511D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C511E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C511F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	C511G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C511H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C511I	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C511K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C511L	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C511M	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C511N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C511P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C511Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C511R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C511S	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C511T	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C511V	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	C511W	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	C511Y	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	A512C	Neutral	0.089
NOTCH3	Q9UM47-1.2	A512D	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	A512E	Neutral	0.291
NOTCH3	Q9UM47-1.2	A512F	Pathogenic	0.629
NOTCH3	Q9UM47-1.2	A512G	Neutral	0.089
NOTCH3	Q9UM47-1.2	A512H	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	A512I	Neutral	0.28
NOTCH3	Q9UM47-1.2	A512K	Neutral	0.271
NOTCH3	Q9UM47-1.2	A512L	Neutral	0.28
NOTCH3	Q9UM47-1.2	A512M	Neutral	0.279
NOTCH3	Q9UM47-1.2	A512N	Pathogenic	0.662
NOTCH3	Q9UM47-1.2	A512P	Neutral	0.305
NOTCH3	Q9UM47-1.2	A512Q	Neutral	0.286
NOTCH3	Q9UM47-1.2	A512R	Neutral	0.261
NOTCH3	Q9UM47-1.2	A512S	Neutral	0.022
NOTCH3	Q9UM47-1.2	A512T	Neutral	0.087
NOTCH3	Q9UM47-1.2	A512V	Neutral	0.084
NOTCH3	Q9UM47-1.2	A512W	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	A512Y	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	S513A	Neutral	0.103
NOTCH3	Q9UM47-1.2	S513C	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	S513D	Neutral	0.334
NOTCH3	Q9UM47-1.2	S513E	Neutral	0.318
NOTCH3	Q9UM47-1.2	S513F	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	S513G	Neutral	0.326
NOTCH3	Q9UM47-1.2	S513H	Pathogenic	0.671
NOTCH3	Q9UM47-1.2	S513I	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	S513K	Neutral	0.297
NOTCH3	Q9UM47-1.2	S513L	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	S513M	Pathogenic	0.668
NOTCH3	Q9UM47-1.2	S513N	Neutral	0.097
NOTCH3	Q9UM47-1.2	S513P	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	S513Q	Neutral	0.313
NOTCH3	Q9UM47-1.2	S513R	Pathogenic	0.647
NOTCH3	Q9UM47-1.2	S513T	Neutral	0.098
NOTCH3	Q9UM47-1.2	S513V	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	S513W	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	S513Y	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	T514A	Neutral	0.277
NOTCH3	Q9UM47-1.2	T514C	Pathogenic	0.654
NOTCH3	Q9UM47-1.2	T514D	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	T514E	Pathogenic	0.646
NOTCH3	Q9UM47-1.2	T514F	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	T514G	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	T514H	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	T514I	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	T514K	Pathogenic	0.624
NOTCH3	Q9UM47-1.2	T514L	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	T514M	Pathogenic	0.633
NOTCH3	Q9UM47-1.2	T514N	Neutral	0.297
NOTCH3	Q9UM47-1.2	T514P	Pathogenic	0.657
NOTCH3	Q9UM47-1.2	T514Q	Pathogenic	0.641
NOTCH3	Q9UM47-1.2	T514R	Pathogenic	0.612
NOTCH3	Q9UM47-1.2	T514S	Neutral	0.079
NOTCH3	Q9UM47-1.2	T514V	Neutral	0.289
NOTCH3	Q9UM47-1.2	T514W	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	T514Y	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	P515A	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	P515C	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	P515D	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	P515E	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	P515F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P515G	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	P515H	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	P515I	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	P515K	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	P515L	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	P515M	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	P515N	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	P515Q	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	P515R	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	P515S	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	P515T	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	P515V	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	P515W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P515Y	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	C516A	Neutral	0.498
NOTCH3	Q9UM47-1.2	C516D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C516E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C516F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	C516G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C516H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C516I	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C516K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C516L	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C516M	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C516N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C516P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C516Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C516R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C516S	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C516T	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C516V	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C516W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C516Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	R517A	Neutral	0.064
NOTCH3	Q9UM47-1.2	R517C	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	R517D	Neutral	0.254
NOTCH3	Q9UM47-1.2	R517E	Neutral	0.017
NOTCH3	Q9UM47-1.2	R517F	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	R517G	Neutral	0.225
NOTCH3	Q9UM47-1.2	R517H	Neutral	0.018
NOTCH3	Q9UM47-1.2	R517I	Pathogenic	0.643
NOTCH3	Q9UM47-1.2	R517K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R517L	Neutral	0.283
NOTCH3	Q9UM47-1.2	R517M	Neutral	0.08
NOTCH3	Q9UM47-1.2	R517N	Neutral	0.017
NOTCH3	Q9UM47-1.2	R517P	Neutral	0.256
NOTCH3	Q9UM47-1.2	R517Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	R517S	Neutral	0.066
NOTCH3	Q9UM47-1.2	R517T	Neutral	0.071
NOTCH3	Q9UM47-1.2	R517V	Pathogenic	0.625
NOTCH3	Q9UM47-1.2	R517W	Pathogenic	0.652
NOTCH3	Q9UM47-1.2	R517Y	Neutral	0.295
NOTCH3	Q9UM47-1.2	N518A	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	N518C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N518D	Neutral	0.145
NOTCH3	Q9UM47-1.2	N518E	Neutral	0.427
NOTCH3	Q9UM47-1.2	N518F	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N518G	Neutral	0.395
NOTCH3	Q9UM47-1.2	N518H	Neutral	0.137
NOTCH3	Q9UM47-1.2	N518I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N518K	Neutral	0.403
NOTCH3	Q9UM47-1.2	N518L	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N518M	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	N518P	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	N518Q	Neutral	0.423
NOTCH3	Q9UM47-1.2	N518R	Neutral	0.391
NOTCH3	Q9UM47-1.2	N518S	Neutral	0.137
NOTCH3	Q9UM47-1.2	N518T	Neutral	0.438
NOTCH3	Q9UM47-1.2	N518V	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N518W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N518Y	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	G519A	Neutral	0.206
NOTCH3	Q9UM47-1.2	G519C	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G519D	Pathogenic	0.519
NOTCH3	Q9UM47-1.2	G519E	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	G519F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	G519H	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	G519I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G519K	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	G519L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G519M	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	G519N	Neutral	0.189
NOTCH3	Q9UM47-1.2	G519P	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	G519Q	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	G519R	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	G519S	Neutral	0.202
NOTCH3	Q9UM47-1.2	G519T	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G519V	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G519W	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	G519Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	A520C	Neutral	0.276
NOTCH3	Q9UM47-1.2	A520D	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	A520E	Pathogenic	0.614
NOTCH3	Q9UM47-1.2	A520F	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	A520G	Neutral	0.275
NOTCH3	Q9UM47-1.2	A520H	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	A520I	Pathogenic	0.601
NOTCH3	Q9UM47-1.2	A520K	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	A520L	Pathogenic	0.601
NOTCH3	Q9UM47-1.2	A520M	Pathogenic	0.6
NOTCH3	Q9UM47-1.2	A520N	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	A520P	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	A520Q	Pathogenic	0.608
NOTCH3	Q9UM47-1.2	A520R	Pathogenic	0.578
NOTCH3	Q9UM47-1.2	A520S	Neutral	0.081
NOTCH3	Q9UM47-1.2	A520T	Neutral	0.269
NOTCH3	Q9UM47-1.2	A520V	Neutral	0.262
NOTCH3	Q9UM47-1.2	A520W	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	A520Y	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	K521A	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	K521C	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	K521D	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	K521E	Neutral	0.187
NOTCH3	Q9UM47-1.2	K521F	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	K521G	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	K521H	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	K521I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	K521L	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	K521M	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	K521N	Neutral	0.498
NOTCH3	Q9UM47-1.2	K521P	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	K521Q	Neutral	0.19
NOTCH3	Q9UM47-1.2	K521R	Neutral	0.05
NOTCH3	Q9UM47-1.2	K521S	Neutral	0.477
NOTCH3	Q9UM47-1.2	K521T	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	K521V	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	K521W	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	K521Y	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	C522A	Neutral	0.492
NOTCH3	Q9UM47-1.2	C522D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C522E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C522F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C522G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C522H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C522I	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C522K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C522L	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C522M	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C522N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C522P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C522Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C522R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C522S	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C522T	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C522V	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C522W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C522Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	V523A	Neutral	0.012
NOTCH3	Q9UM47-1.2	V523C	Neutral	0.056
NOTCH3	Q9UM47-1.2	V523D	Pathogenic	0.559
NOTCH3	Q9UM47-1.2	V523E	Neutral	0.224
NOTCH3	Q9UM47-1.2	V523F	Neutral	0.054
NOTCH3	Q9UM47-1.2	V523G	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	V523H	Pathogenic	0.558
NOTCH3	Q9UM47-1.2	V523I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V523K	Neutral	0.208
NOTCH3	Q9UM47-1.2	V523L	Neutral	0.003
NOTCH3	Q9UM47-1.2	V523M	Neutral	0.003
NOTCH3	Q9UM47-1.2	V523N	Pathogenic	0.564
NOTCH3	Q9UM47-1.2	V523P	Neutral	0.215
NOTCH3	Q9UM47-1.2	V523Q	Neutral	0.22
NOTCH3	Q9UM47-1.2	V523R	Pathogenic	0.532
NOTCH3	Q9UM47-1.2	V523S	Neutral	0.205
NOTCH3	Q9UM47-1.2	V523T	Neutral	0.013
NOTCH3	Q9UM47-1.2	V523W	Pathogenic	0.515
NOTCH3	Q9UM47-1.2	V523Y	Neutral	0.053
NOTCH3	Q9UM47-1.2	D524A	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	D524C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D524E	Neutral	0.032
NOTCH3	Q9UM47-1.2	D524F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D524G	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	D524H	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	D524I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D524K	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	D524L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D524M	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D524N	Neutral	0.137
NOTCH3	Q9UM47-1.2	D524P	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	D524Q	Neutral	0.403
NOTCH3	Q9UM47-1.2	D524R	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	D524S	Neutral	0.408
NOTCH3	Q9UM47-1.2	D524T	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	D524V	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D524W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D524Y	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	Q525A	Neutral	0.026
NOTCH3	Q9UM47-1.2	Q525C	Neutral	0.378
NOTCH3	Q9UM47-1.2	Q525D	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q525E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q525F	Neutral	0.386
NOTCH3	Q9UM47-1.2	Q525G	Neutral	0.103
NOTCH3	Q9UM47-1.2	Q525H	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q525I	Neutral	0.396
NOTCH3	Q9UM47-1.2	Q525K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q525L	Neutral	0.126
NOTCH3	Q9UM47-1.2	Q525M	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q525N	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q525P	Neutral	0.029
NOTCH3	Q9UM47-1.2	Q525R	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q525S	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q525T	Neutral	0.029
NOTCH3	Q9UM47-1.2	Q525V	Neutral	0.126
NOTCH3	Q9UM47-1.2	Q525W	Neutral	0.111
NOTCH3	Q9UM47-1.2	Q525Y	Neutral	0.029
NOTCH3	Q9UM47-1.2	P526A	Pathogenic	0.535
NOTCH3	Q9UM47-1.2	P526C	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	P526D	Pathogenic	0.558
NOTCH3	Q9UM47-1.2	P526E	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	P526F	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	P526G	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	P526H	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	P526I	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	P526K	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	P526L	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	P526M	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	P526N	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	P526Q	Pathogenic	0.535
NOTCH3	Q9UM47-1.2	P526R	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	P526S	Pathogenic	0.541
NOTCH3	Q9UM47-1.2	P526T	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	P526V	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	P526W	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	P526Y	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	D527A	Neutral	0.145
NOTCH3	Q9UM47-1.2	D527C	Neutral	0.456
NOTCH3	Q9UM47-1.2	D527E	Neutral	0.0
NOTCH3	Q9UM47-1.2	D527F	Neutral	0.42
NOTCH3	Q9UM47-1.2	D527G	Neutral	0.033
NOTCH3	Q9UM47-1.2	D527H	Neutral	0.036
NOTCH3	Q9UM47-1.2	D527I	Neutral	0.431
NOTCH3	Q9UM47-1.2	D527K	Neutral	0.033
NOTCH3	Q9UM47-1.2	D527L	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	D527M	Neutral	0.43
NOTCH3	Q9UM47-1.2	D527N	Neutral	0.002
NOTCH3	Q9UM47-1.2	D527P	Neutral	0.039
NOTCH3	Q9UM47-1.2	D527Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	D527R	Neutral	0.129
NOTCH3	Q9UM47-1.2	D527S	Neutral	0.008
NOTCH3	Q9UM47-1.2	D527T	Neutral	0.039
NOTCH3	Q9UM47-1.2	D527V	Neutral	0.448
NOTCH3	Q9UM47-1.2	D527W	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	D527Y	Neutral	0.413
NOTCH3	Q9UM47-1.2	G528A	Neutral	0.03
NOTCH3	Q9UM47-1.2	G528C	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	G528D	Neutral	0.115
NOTCH3	Q9UM47-1.2	G528E	Neutral	0.356
NOTCH3	Q9UM47-1.2	G528F	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	G528H	Neutral	0.347
NOTCH3	Q9UM47-1.2	G528I	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	G528K	Neutral	0.334
NOTCH3	Q9UM47-1.2	G528L	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	G528M	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	G528N	Neutral	0.027
NOTCH3	Q9UM47-1.2	G528P	Neutral	0.373
NOTCH3	Q9UM47-1.2	G528Q	Neutral	0.351
NOTCH3	Q9UM47-1.2	G528R	Neutral	0.323
NOTCH3	Q9UM47-1.2	G528S	Neutral	0.03
NOTCH3	Q9UM47-1.2	G528T	Neutral	0.37
NOTCH3	Q9UM47-1.2	G528V	Pathogenic	0.72
NOTCH3	Q9UM47-1.2	G528W	Neutral	0.313
NOTCH3	Q9UM47-1.2	G528Y	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	Y529A	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	Y529C	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	Y529D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	Y529E	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	Y529F	Neutral	0.029
NOTCH3	Q9UM47-1.2	Y529G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	Y529H	Neutral	0.112
NOTCH3	Q9UM47-1.2	Y529I	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	Y529K	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	Y529L	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	Y529M	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	Y529N	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	Y529P	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	Y529Q	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	Y529R	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	Y529S	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	Y529T	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	Y529V	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	Y529W	Neutral	0.113
NOTCH3	Q9UM47-1.2	E530A	Neutral	0.259
NOTCH3	Q9UM47-1.2	E530C	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	E530D	Neutral	0.004
NOTCH3	Q9UM47-1.2	E530F	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	E530G	Pathogenic	0.596
NOTCH3	Q9UM47-1.2	E530H	Neutral	0.08
NOTCH3	Q9UM47-1.2	E530I	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	E530K	Neutral	0.018
NOTCH3	Q9UM47-1.2	E530L	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	E530M	Pathogenic	0.64
NOTCH3	Q9UM47-1.2	E530N	Neutral	0.079
NOTCH3	Q9UM47-1.2	E530P	Neutral	0.277
NOTCH3	Q9UM47-1.2	E530Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	E530R	Neutral	0.072
NOTCH3	Q9UM47-1.2	E530S	Neutral	0.073
NOTCH3	Q9UM47-1.2	E530T	Neutral	0.279
NOTCH3	Q9UM47-1.2	E530V	Pathogenic	0.65
NOTCH3	Q9UM47-1.2	E530W	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	E530Y	Pathogenic	0.625
NOTCH3	Q9UM47-1.2	C531A	Neutral	0.492
NOTCH3	Q9UM47-1.2	C531D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C531E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C531F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C531G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C531H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C531I	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C531K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C531L	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C531M	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C531N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C531P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C531Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C531R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C531S	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C531T	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C531V	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C531W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C531Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	R532A	Neutral	0.048
NOTCH3	Q9UM47-1.2	R532C	Pathogenic	0.529
NOTCH3	Q9UM47-1.2	R532D	Neutral	0.199
NOTCH3	Q9UM47-1.2	R532E	Neutral	0.013
NOTCH3	Q9UM47-1.2	R532F	Pathogenic	0.577
NOTCH3	Q9UM47-1.2	R532G	Neutral	0.174
NOTCH3	Q9UM47-1.2	R532H	Neutral	0.013
NOTCH3	Q9UM47-1.2	R532I	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	R532K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R532L	Neutral	0.223
NOTCH3	Q9UM47-1.2	R532M	Neutral	0.059
NOTCH3	Q9UM47-1.2	R532N	Neutral	0.012
NOTCH3	Q9UM47-1.2	R532P	Neutral	0.2
NOTCH3	Q9UM47-1.2	R532Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R532S	Neutral	0.049
NOTCH3	Q9UM47-1.2	R532T	Neutral	0.052
NOTCH3	Q9UM47-1.2	R532V	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	R532W	Pathogenic	0.576
NOTCH3	Q9UM47-1.2	R532Y	Neutral	0.234
NOTCH3	Q9UM47-1.2	C533A	Neutral	0.498
NOTCH3	Q9UM47-1.2	C533D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C533E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C533F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	C533G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C533H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C533I	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C533K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C533L	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C533M	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C533N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C533P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C533Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C533R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C533S	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C533T	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C533V	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C533W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C533Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	A534C	Neutral	0.077
NOTCH3	Q9UM47-1.2	A534D	Pathogenic	0.629
NOTCH3	Q9UM47-1.2	A534E	Neutral	0.258
NOTCH3	Q9UM47-1.2	A534F	Pathogenic	0.589
NOTCH3	Q9UM47-1.2	A534G	Neutral	0.077
NOTCH3	Q9UM47-1.2	A534H	Pathogenic	0.603
NOTCH3	Q9UM47-1.2	A534I	Neutral	0.248
NOTCH3	Q9UM47-1.2	A534K	Neutral	0.24
NOTCH3	Q9UM47-1.2	A534L	Neutral	0.247
NOTCH3	Q9UM47-1.2	A534M	Neutral	0.247
NOTCH3	Q9UM47-1.2	A534N	Pathogenic	0.624
NOTCH3	Q9UM47-1.2	A534P	Neutral	0.271
NOTCH3	Q9UM47-1.2	A534Q	Neutral	0.253
NOTCH3	Q9UM47-1.2	A534R	Neutral	0.231
NOTCH3	Q9UM47-1.2	A534S	Neutral	0.019
NOTCH3	Q9UM47-1.2	A534T	Neutral	0.075
NOTCH3	Q9UM47-1.2	A534V	Neutral	0.072
NOTCH3	Q9UM47-1.2	A534W	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	A534Y	Pathogenic	0.582
NOTCH3	Q9UM47-1.2	E535A	Neutral	0.397
NOTCH3	Q9UM47-1.2	E535C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	E535D	Neutral	0.008
NOTCH3	Q9UM47-1.2	E535F	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	E535G	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	E535H	Neutral	0.141
NOTCH3	Q9UM47-1.2	E535I	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	E535K	Neutral	0.033
NOTCH3	Q9UM47-1.2	E535L	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	E535M	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	E535N	Neutral	0.138
NOTCH3	Q9UM47-1.2	E535P	Neutral	0.419
NOTCH3	Q9UM47-1.2	E535Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	E535R	Neutral	0.127
NOTCH3	Q9UM47-1.2	E535S	Neutral	0.129
NOTCH3	Q9UM47-1.2	E535T	Neutral	0.421
NOTCH3	Q9UM47-1.2	E535V	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	E535W	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	E535Y	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	G536A	Neutral	0.245
NOTCH3	Q9UM47-1.2	G536C	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	G536D	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	G536E	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	G536F	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G536H	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	G536I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G536K	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	G536L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G536M	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G536N	Neutral	0.226
NOTCH3	Q9UM47-1.2	G536P	Pathogenic	0.861
NOTCH3	Q9UM47-1.2	G536Q	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	G536R	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	G536S	Neutral	0.241
NOTCH3	Q9UM47-1.2	G536T	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	G536V	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G536W	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	G536Y	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	F537A	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	F537C	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	F537D	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	F537E	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	F537G	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	F537H	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	F537I	Neutral	0.455
NOTCH3	Q9UM47-1.2	F537K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	F537L	Neutral	0.455
NOTCH3	Q9UM47-1.2	F537M	Neutral	0.456
NOTCH3	Q9UM47-1.2	F537N	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	F537P	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F537Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	F537R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	F537S	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	F537T	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	F537V	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	F537W	Neutral	0.147
NOTCH3	Q9UM47-1.2	F537Y	Neutral	0.009
NOTCH3	Q9UM47-1.2	E538A	Neutral	0.094
NOTCH3	Q9UM47-1.2	E538C	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	E538D	Neutral	0.001
NOTCH3	Q9UM47-1.2	E538F	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	E538G	Neutral	0.305
NOTCH3	Q9UM47-1.2	E538H	Neutral	0.025
NOTCH3	Q9UM47-1.2	E538I	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	E538K	Neutral	0.005
NOTCH3	Q9UM47-1.2	E538L	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	E538M	Neutral	0.346
NOTCH3	Q9UM47-1.2	E538N	Neutral	0.025
NOTCH3	Q9UM47-1.2	E538P	Neutral	0.102
NOTCH3	Q9UM47-1.2	E538Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	E538R	Neutral	0.023
NOTCH3	Q9UM47-1.2	E538S	Neutral	0.023
NOTCH3	Q9UM47-1.2	E538T	Neutral	0.103
NOTCH3	Q9UM47-1.2	E538V	Neutral	0.356
NOTCH3	Q9UM47-1.2	E538W	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	E538Y	Neutral	0.331
NOTCH3	Q9UM47-1.2	G539A	Neutral	0.23
NOTCH3	Q9UM47-1.2	G539C	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G539D	Pathogenic	0.555
NOTCH3	Q9UM47-1.2	G539E	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	G539F	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G539H	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	G539I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G539K	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	G539L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G539M	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G539N	Neutral	0.211
NOTCH3	Q9UM47-1.2	G539P	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	G539Q	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	G539R	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	G539S	Neutral	0.226
NOTCH3	Q9UM47-1.2	G539T	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	G539V	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G539W	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	G539Y	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	T540A	Neutral	0.011
NOTCH3	Q9UM47-1.2	T540C	Neutral	0.05
NOTCH3	Q9UM47-1.2	T540D	Neutral	0.051
NOTCH3	Q9UM47-1.2	T540E	Neutral	0.049
NOTCH3	Q9UM47-1.2	T540F	Neutral	0.175
NOTCH3	Q9UM47-1.2	T540G	Neutral	0.172
NOTCH3	Q9UM47-1.2	T540H	Neutral	0.183
NOTCH3	Q9UM47-1.2	T540I	Neutral	0.046
NOTCH3	Q9UM47-1.2	T540K	Neutral	0.044
NOTCH3	Q9UM47-1.2	T540L	Neutral	0.046
NOTCH3	Q9UM47-1.2	T540M	Neutral	0.046
NOTCH3	Q9UM47-1.2	T540N	Neutral	0.012
NOTCH3	Q9UM47-1.2	T540P	Neutral	0.051
NOTCH3	Q9UM47-1.2	T540Q	Neutral	0.048
NOTCH3	Q9UM47-1.2	T540R	Neutral	0.042
NOTCH3	Q9UM47-1.2	T540S	Neutral	0.002
NOTCH3	Q9UM47-1.2	T540V	Neutral	0.011
NOTCH3	Q9UM47-1.2	T540W	Neutral	0.16
NOTCH3	Q9UM47-1.2	T540Y	Neutral	0.17
NOTCH3	Q9UM47-1.2	L541A	Neutral	0.188
NOTCH3	Q9UM47-1.2	L541C	Neutral	0.199
NOTCH3	Q9UM47-1.2	L541D	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	L541E	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	L541F	Neutral	0.057
NOTCH3	Q9UM47-1.2	L541G	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	L541H	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	L541I	Neutral	0.003
NOTCH3	Q9UM47-1.2	L541K	Pathogenic	0.56
NOTCH3	Q9UM47-1.2	L541M	Neutral	0.003
NOTCH3	Q9UM47-1.2	L541N	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	L541P	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	L541Q	Pathogenic	0.56
NOTCH3	Q9UM47-1.2	L541R	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	L541S	Pathogenic	0.52
NOTCH3	Q9UM47-1.2	L541T	Neutral	0.204
NOTCH3	Q9UM47-1.2	L541V	Neutral	0.013
NOTCH3	Q9UM47-1.2	L541W	Pathogenic	0.529
NOTCH3	Q9UM47-1.2	L541Y	Neutral	0.212
NOTCH3	Q9UM47-1.2	C542A	Neutral	0.494
NOTCH3	Q9UM47-1.2	C542D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C542E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C542F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C542G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C542H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C542I	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C542K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C542L	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C542M	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C542N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C542P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C542Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C542R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C542S	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C542T	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C542V	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C542W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C542Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	D543A	Neutral	0.011
NOTCH3	Q9UM47-1.2	D543C	Neutral	0.052
NOTCH3	Q9UM47-1.2	D543E	Neutral	0.0
NOTCH3	Q9UM47-1.2	D543F	Neutral	0.045
NOTCH3	Q9UM47-1.2	D543G	Neutral	0.002
NOTCH3	Q9UM47-1.2	D543H	Neutral	0.002
NOTCH3	Q9UM47-1.2	D543I	Neutral	0.047
NOTCH3	Q9UM47-1.2	D543K	Neutral	0.002
NOTCH3	Q9UM47-1.2	D543L	Neutral	0.184
NOTCH3	Q9UM47-1.2	D543M	Neutral	0.047
NOTCH3	Q9UM47-1.2	D543N	Neutral	0.0
NOTCH3	Q9UM47-1.2	D543P	Neutral	0.003
NOTCH3	Q9UM47-1.2	D543Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	D543R	Neutral	0.01
NOTCH3	Q9UM47-1.2	D543S	Neutral	0.001
NOTCH3	Q9UM47-1.2	D543T	Neutral	0.003
NOTCH3	Q9UM47-1.2	D543V	Neutral	0.05
NOTCH3	Q9UM47-1.2	D543W	Neutral	0.163
NOTCH3	Q9UM47-1.2	D543Y	Neutral	0.044
NOTCH3	Q9UM47-1.2	R544A	Neutral	0.015
NOTCH3	Q9UM47-1.2	R544C	Neutral	0.256
NOTCH3	Q9UM47-1.2	R544D	Neutral	0.071
NOTCH3	Q9UM47-1.2	R544E	Neutral	0.004
NOTCH3	Q9UM47-1.2	R544F	Neutral	0.296
NOTCH3	Q9UM47-1.2	R544G	Neutral	0.061
NOTCH3	Q9UM47-1.2	R544H	Neutral	0.004
NOTCH3	Q9UM47-1.2	R544I	Neutral	0.287
NOTCH3	Q9UM47-1.2	R544K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R544L	Neutral	0.081
NOTCH3	Q9UM47-1.2	R544M	Neutral	0.019
NOTCH3	Q9UM47-1.2	R544N	Neutral	0.004
NOTCH3	Q9UM47-1.2	R544P	Neutral	0.071
NOTCH3	Q9UM47-1.2	R544Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	R544S	Neutral	0.015
NOTCH3	Q9UM47-1.2	R544T	Neutral	0.017
NOTCH3	Q9UM47-1.2	R544V	Neutral	0.271
NOTCH3	Q9UM47-1.2	R544W	Neutral	0.295
NOTCH3	Q9UM47-1.2	R544Y	Neutral	0.086
NOTCH3	Q9UM47-1.2	N545A	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	N545C	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	N545D	Neutral	0.036
NOTCH3	Q9UM47-1.2	N545E	Neutral	0.14
NOTCH3	Q9UM47-1.2	N545F	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	N545G	Neutral	0.125
NOTCH3	Q9UM47-1.2	N545H	Neutral	0.034
NOTCH3	Q9UM47-1.2	N545I	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	N545K	Neutral	0.129
NOTCH3	Q9UM47-1.2	N545L	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	N545M	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	N545P	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	N545Q	Neutral	0.138
NOTCH3	Q9UM47-1.2	N545R	Neutral	0.123
NOTCH3	Q9UM47-1.2	N545S	Neutral	0.033
NOTCH3	Q9UM47-1.2	N545T	Neutral	0.146
NOTCH3	Q9UM47-1.2	N545V	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	N545W	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	N545Y	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	V546A	Neutral	0.026
NOTCH3	Q9UM47-1.2	V546C	Neutral	0.114
NOTCH3	Q9UM47-1.2	V546D	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	V546E	Neutral	0.386
NOTCH3	Q9UM47-1.2	V546F	Neutral	0.11
NOTCH3	Q9UM47-1.2	V546G	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	V546H	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	V546I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V546K	Neutral	0.363
NOTCH3	Q9UM47-1.2	V546L	Neutral	0.006
NOTCH3	Q9UM47-1.2	V546M	Neutral	0.006
NOTCH3	Q9UM47-1.2	V546N	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	V546P	Neutral	0.373
NOTCH3	Q9UM47-1.2	V546Q	Neutral	0.38
NOTCH3	Q9UM47-1.2	V546R	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	V546S	Neutral	0.359
NOTCH3	Q9UM47-1.2	V546T	Neutral	0.028
NOTCH3	Q9UM47-1.2	V546W	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	V546Y	Neutral	0.107
NOTCH3	Q9UM47-1.2	D547A	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	D547C	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	D547E	Neutral	0.005
NOTCH3	Q9UM47-1.2	D547F	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	D547G	Neutral	0.318
NOTCH3	Q9UM47-1.2	D547H	Neutral	0.332
NOTCH3	Q9UM47-1.2	D547I	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	D547K	Neutral	0.317
NOTCH3	Q9UM47-1.2	D547L	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	D547M	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	D547N	Neutral	0.025
NOTCH3	Q9UM47-1.2	D547P	Neutral	0.356
NOTCH3	Q9UM47-1.2	D547Q	Neutral	0.1
NOTCH3	Q9UM47-1.2	D547R	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	D547S	Neutral	0.101
NOTCH3	Q9UM47-1.2	D547T	Neutral	0.354
NOTCH3	Q9UM47-1.2	D547V	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	D547W	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	D547Y	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	D548A	Neutral	0.328
NOTCH3	Q9UM47-1.2	D548C	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	D548E	Neutral	0.001
NOTCH3	Q9UM47-1.2	D548F	Pathogenic	0.675
NOTCH3	Q9UM47-1.2	D548G	Neutral	0.09
NOTCH3	Q9UM47-1.2	D548H	Neutral	0.096
NOTCH3	Q9UM47-1.2	D548I	Pathogenic	0.685
NOTCH3	Q9UM47-1.2	D548K	Neutral	0.09
NOTCH3	Q9UM47-1.2	D548L	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	D548M	Pathogenic	0.684
NOTCH3	Q9UM47-1.2	D548N	Neutral	0.005
NOTCH3	Q9UM47-1.2	D548P	Neutral	0.105
NOTCH3	Q9UM47-1.2	D548Q	Neutral	0.023
NOTCH3	Q9UM47-1.2	D548R	Neutral	0.299
NOTCH3	Q9UM47-1.2	D548S	Neutral	0.023
NOTCH3	Q9UM47-1.2	D548T	Neutral	0.104
NOTCH3	Q9UM47-1.2	D548V	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	D548W	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	D548Y	Pathogenic	0.669
NOTCH3	Q9UM47-1.2	C549A	Pathogenic	0.502
NOTCH3	Q9UM47-1.2	C549D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C549E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C549F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	C549G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C549H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C549I	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C549K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C549L	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C549M	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C549N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C549P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C549Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C549R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C549S	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C549T	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	C549V	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	C549W	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	C549Y	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	S550A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S550C	Neutral	0.015
NOTCH3	Q9UM47-1.2	S550D	Neutral	0.003
NOTCH3	Q9UM47-1.2	S550E	Neutral	0.003
NOTCH3	Q9UM47-1.2	S550F	Neutral	0.053
NOTCH3	Q9UM47-1.2	S550G	Neutral	0.003
NOTCH3	Q9UM47-1.2	S550H	Neutral	0.013
NOTCH3	Q9UM47-1.2	S550I	Neutral	0.055
NOTCH3	Q9UM47-1.2	S550K	Neutral	0.003
NOTCH3	Q9UM47-1.2	S550L	Neutral	0.055
NOTCH3	Q9UM47-1.2	S550M	Neutral	0.013
NOTCH3	Q9UM47-1.2	S550N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S550P	Neutral	0.014
NOTCH3	Q9UM47-1.2	S550Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	S550R	Neutral	0.011
NOTCH3	Q9UM47-1.2	S550T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S550V	Neutral	0.059
NOTCH3	Q9UM47-1.2	S550W	Neutral	0.187
NOTCH3	Q9UM47-1.2	S550Y	Neutral	0.051
NOTCH3	Q9UM47-1.2	P551A	Neutral	0.461
NOTCH3	Q9UM47-1.2	P551C	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	P551D	Neutral	0.484
NOTCH3	Q9UM47-1.2	P551E	Neutral	0.467
NOTCH3	Q9UM47-1.2	P551F	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	P551G	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	P551H	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	P551I	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	P551K	Neutral	0.443
NOTCH3	Q9UM47-1.2	P551L	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	P551M	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	P551N	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	P551Q	Neutral	0.461
NOTCH3	Q9UM47-1.2	P551R	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	P551S	Neutral	0.468
NOTCH3	Q9UM47-1.2	P551T	Neutral	0.48
NOTCH3	Q9UM47-1.2	P551V	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	P551W	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	P551Y	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	D552A	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	D552C	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	D552E	Neutral	0.009
NOTCH3	Q9UM47-1.2	D552F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	D552G	Neutral	0.443
NOTCH3	Q9UM47-1.2	D552H	Neutral	0.458
NOTCH3	Q9UM47-1.2	D552I	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	D552K	Neutral	0.44
NOTCH3	Q9UM47-1.2	D552L	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	D552M	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	D552N	Neutral	0.042
NOTCH3	Q9UM47-1.2	D552P	Neutral	0.484
NOTCH3	Q9UM47-1.2	D552Q	Neutral	0.158
NOTCH3	Q9UM47-1.2	D552R	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	D552S	Neutral	0.161
NOTCH3	Q9UM47-1.2	D552T	Neutral	0.482
NOTCH3	Q9UM47-1.2	D552V	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	D552W	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D552Y	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	P553A	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	P553C	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	P553D	Pathogenic	0.702
NOTCH3	Q9UM47-1.2	P553E	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	P553F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P553G	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	P553H	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	P553I	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	P553K	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	P553L	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	P553M	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	P553N	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	P553Q	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	P553R	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	P553S	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	P553T	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	P553V	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	P553W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P553Y	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	C554A	Neutral	0.483
NOTCH3	Q9UM47-1.2	C554D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C554E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C554F	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C554G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C554H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C554I	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	C554K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C554L	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	C554M	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	C554N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C554P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C554Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C554R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C554S	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C554T	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	C554V	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C554W	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	C554Y	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	H555A	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	H555C	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	H555D	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	H555E	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	H555F	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	H555G	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	H555I	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	H555K	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	H555L	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	H555M	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	H555N	Neutral	0.31
NOTCH3	Q9UM47-1.2	H555P	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	H555Q	Pathogenic	0.686
NOTCH3	Q9UM47-1.2	H555R	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	H555S	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	H555T	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	H555V	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	H555W	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	H555Y	Neutral	0.09
NOTCH3	Q9UM47-1.2	H556A	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	H556C	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	H556D	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	H556E	Neutral	0.241
NOTCH3	Q9UM47-1.2	H556F	Pathogenic	0.586
NOTCH3	Q9UM47-1.2	H556G	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	H556I	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	H556K	Pathogenic	0.585
NOTCH3	Q9UM47-1.2	H556L	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	H556M	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	H556N	Neutral	0.062
NOTCH3	Q9UM47-1.2	H556P	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	H556Q	Neutral	0.244
NOTCH3	Q9UM47-1.2	H556R	Neutral	0.227
NOTCH3	Q9UM47-1.2	H556S	Pathogenic	0.556
NOTCH3	Q9UM47-1.2	H556T	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	H556V	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	H556W	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	H556Y	Neutral	0.014
NOTCH3	Q9UM47-1.2	G557A	Neutral	0.237
NOTCH3	Q9UM47-1.2	G557C	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	G557D	Pathogenic	0.564
NOTCH3	Q9UM47-1.2	G557E	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G557F	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G557H	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	G557I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G557K	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	G557L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G557M	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G557N	Neutral	0.218
NOTCH3	Q9UM47-1.2	G557P	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	G557Q	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	G557R	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	G557S	Neutral	0.233
NOTCH3	Q9UM47-1.2	G557T	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	G557V	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	G557W	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	G557Y	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	R558A	Neutral	0.017
NOTCH3	Q9UM47-1.2	R558C	Neutral	0.281
NOTCH3	Q9UM47-1.2	R558D	Neutral	0.08
NOTCH3	Q9UM47-1.2	R558E	Neutral	0.004
NOTCH3	Q9UM47-1.2	R558F	Neutral	0.323
NOTCH3	Q9UM47-1.2	R558G	Neutral	0.069
NOTCH3	Q9UM47-1.2	R558H	Neutral	0.005
NOTCH3	Q9UM47-1.2	R558I	Neutral	0.313
NOTCH3	Q9UM47-1.2	R558K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R558L	Neutral	0.091
NOTCH3	Q9UM47-1.2	R558M	Neutral	0.021
NOTCH3	Q9UM47-1.2	R558N	Neutral	0.004
NOTCH3	Q9UM47-1.2	R558P	Neutral	0.08
NOTCH3	Q9UM47-1.2	R558Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	R558S	Neutral	0.018
NOTCH3	Q9UM47-1.2	R558T	Neutral	0.019
NOTCH3	Q9UM47-1.2	R558V	Neutral	0.297
NOTCH3	Q9UM47-1.2	R558W	Neutral	0.322
NOTCH3	Q9UM47-1.2	R558Y	Neutral	0.096
NOTCH3	Q9UM47-1.2	C559A	Neutral	0.496
NOTCH3	Q9UM47-1.2	C559D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C559E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C559F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	C559G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C559H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C559I	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C559K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C559L	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C559M	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	C559N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C559P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C559Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C559R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C559S	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C559T	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C559V	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	C559W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C559Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	V560A	Neutral	0.009
NOTCH3	Q9UM47-1.2	V560C	Neutral	0.043
NOTCH3	Q9UM47-1.2	V560D	Neutral	0.49
NOTCH3	Q9UM47-1.2	V560E	Neutral	0.18
NOTCH3	Q9UM47-1.2	V560F	Neutral	0.041
NOTCH3	Q9UM47-1.2	V560G	Neutral	0.447
NOTCH3	Q9UM47-1.2	V560H	Neutral	0.489
NOTCH3	Q9UM47-1.2	V560I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V560K	Neutral	0.166
NOTCH3	Q9UM47-1.2	V560L	Neutral	0.002
NOTCH3	Q9UM47-1.2	V560M	Neutral	0.002
NOTCH3	Q9UM47-1.2	V560N	Neutral	0.494
NOTCH3	Q9UM47-1.2	V560P	Neutral	0.172
NOTCH3	Q9UM47-1.2	V560Q	Neutral	0.176
NOTCH3	Q9UM47-1.2	V560R	Neutral	0.462
NOTCH3	Q9UM47-1.2	V560S	Neutral	0.164
NOTCH3	Q9UM47-1.2	V560T	Neutral	0.01
NOTCH3	Q9UM47-1.2	V560W	Neutral	0.446
NOTCH3	Q9UM47-1.2	V560Y	Neutral	0.04
NOTCH3	Q9UM47-1.2	D561A	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	D561C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D561E	Neutral	0.032
NOTCH3	Q9UM47-1.2	D561F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D561G	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	D561H	Pathogenic	0.753
NOTCH3	Q9UM47-1.2	D561I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D561K	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	D561L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D561M	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D561N	Neutral	0.137
NOTCH3	Q9UM47-1.2	D561P	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	D561Q	Neutral	0.404
NOTCH3	Q9UM47-1.2	D561R	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	D561S	Neutral	0.409
NOTCH3	Q9UM47-1.2	D561T	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	D561V	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D561W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D561Y	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	G562A	Neutral	0.19
NOTCH3	Q9UM47-1.2	G562C	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G562D	Neutral	0.494
NOTCH3	Q9UM47-1.2	G562E	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	G562F	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	G562H	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	G562I	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	G562K	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	G562L	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	G562M	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	G562N	Neutral	0.174
NOTCH3	Q9UM47-1.2	G562P	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	G562Q	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	G562R	Pathogenic	0.782
NOTCH3	Q9UM47-1.2	G562S	Neutral	0.186
NOTCH3	Q9UM47-1.2	G562T	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	G562V	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	G562W	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	G562Y	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	I563A	Pathogenic	0.62
NOTCH3	Q9UM47-1.2	I563C	Pathogenic	0.636
NOTCH3	Q9UM47-1.2	I563D	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	I563E	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	I563F	Neutral	0.297
NOTCH3	Q9UM47-1.2	I563G	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	I563H	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	I563K	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	I563L	Neutral	0.021
NOTCH3	Q9UM47-1.2	I563M	Neutral	0.089
NOTCH3	Q9UM47-1.2	I563N	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	I563P	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	I563Q	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	I563R	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	I563S	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	I563T	Pathogenic	0.644
NOTCH3	Q9UM47-1.2	I563V	Neutral	0.004
NOTCH3	Q9UM47-1.2	I563W	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	I563Y	Pathogenic	0.655
NOTCH3	Q9UM47-1.2	A564C	Neutral	0.104
NOTCH3	Q9UM47-1.2	A564D	Pathogenic	0.702
NOTCH3	Q9UM47-1.2	A564E	Neutral	0.326
NOTCH3	Q9UM47-1.2	A564F	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	A564G	Neutral	0.103
NOTCH3	Q9UM47-1.2	A564H	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	A564I	Neutral	0.314
NOTCH3	Q9UM47-1.2	A564K	Neutral	0.305
NOTCH3	Q9UM47-1.2	A564L	Neutral	0.314
NOTCH3	Q9UM47-1.2	A564M	Neutral	0.313
NOTCH3	Q9UM47-1.2	A564N	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	A564P	Neutral	0.341
NOTCH3	Q9UM47-1.2	A564Q	Neutral	0.321
NOTCH3	Q9UM47-1.2	A564R	Neutral	0.294
NOTCH3	Q9UM47-1.2	A564S	Neutral	0.026
NOTCH3	Q9UM47-1.2	A564T	Neutral	0.101
NOTCH3	Q9UM47-1.2	A564V	Neutral	0.097
NOTCH3	Q9UM47-1.2	A564W	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	A564Y	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	S565A	Neutral	0.019
NOTCH3	Q9UM47-1.2	S565C	Neutral	0.286
NOTCH3	Q9UM47-1.2	S565D	Neutral	0.079
NOTCH3	Q9UM47-1.2	S565E	Neutral	0.074
NOTCH3	Q9UM47-1.2	S565F	Pathogenic	0.604
NOTCH3	Q9UM47-1.2	S565G	Neutral	0.077
NOTCH3	Q9UM47-1.2	S565H	Neutral	0.261
NOTCH3	Q9UM47-1.2	S565I	Pathogenic	0.614
NOTCH3	Q9UM47-1.2	S565K	Neutral	0.068
NOTCH3	Q9UM47-1.2	S565L	Pathogenic	0.614
NOTCH3	Q9UM47-1.2	S565M	Neutral	0.258
NOTCH3	Q9UM47-1.2	S565N	Neutral	0.018
NOTCH3	Q9UM47-1.2	S565P	Neutral	0.283
NOTCH3	Q9UM47-1.2	S565Q	Neutral	0.073
NOTCH3	Q9UM47-1.2	S565R	Neutral	0.24
NOTCH3	Q9UM47-1.2	S565T	Neutral	0.018
NOTCH3	Q9UM47-1.2	S565V	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	S565W	Pathogenic	0.862
NOTCH3	Q9UM47-1.2	S565Y	Pathogenic	0.596
NOTCH3	Q9UM47-1.2	F566A	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	F566C	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	F566D	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	F566E	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	F566G	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	F566H	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	F566I	Neutral	0.472
NOTCH3	Q9UM47-1.2	F566K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	F566L	Neutral	0.472
NOTCH3	Q9UM47-1.2	F566M	Neutral	0.473
NOTCH3	Q9UM47-1.2	F566N	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	F566P	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F566Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	F566R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	F566S	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	F566T	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	F566V	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	F566W	Neutral	0.156
NOTCH3	Q9UM47-1.2	F566Y	Neutral	0.01
NOTCH3	Q9UM47-1.2	S567A	Neutral	0.004
NOTCH3	Q9UM47-1.2	S567C	Neutral	0.08
NOTCH3	Q9UM47-1.2	S567D	Neutral	0.018
NOTCH3	Q9UM47-1.2	S567E	Neutral	0.017
NOTCH3	Q9UM47-1.2	S567F	Neutral	0.248
NOTCH3	Q9UM47-1.2	S567G	Neutral	0.018
NOTCH3	Q9UM47-1.2	S567H	Neutral	0.071
NOTCH3	Q9UM47-1.2	S567I	Neutral	0.256
NOTCH3	Q9UM47-1.2	S567K	Neutral	0.016
NOTCH3	Q9UM47-1.2	S567L	Neutral	0.256
NOTCH3	Q9UM47-1.2	S567M	Neutral	0.07
NOTCH3	Q9UM47-1.2	S567N	Neutral	0.004
NOTCH3	Q9UM47-1.2	S567P	Neutral	0.079
NOTCH3	Q9UM47-1.2	S567Q	Neutral	0.017
NOTCH3	Q9UM47-1.2	S567R	Neutral	0.064
NOTCH3	Q9UM47-1.2	S567T	Neutral	0.004
NOTCH3	Q9UM47-1.2	S567V	Neutral	0.27
NOTCH3	Q9UM47-1.2	S567W	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	S567Y	Neutral	0.243
NOTCH3	Q9UM47-1.2	C568A	Neutral	0.491
NOTCH3	Q9UM47-1.2	C568D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C568E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C568F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C568G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C568H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C568I	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C568K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C568L	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C568M	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C568N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C568P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C568Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C568R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C568S	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C568T	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C568V	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C568W	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	C568Y	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	A569C	Neutral	0.002
NOTCH3	Q9UM47-1.2	A569D	Neutral	0.041
NOTCH3	Q9UM47-1.2	A569E	Neutral	0.009
NOTCH3	Q9UM47-1.2	A569F	Neutral	0.035
NOTCH3	Q9UM47-1.2	A569G	Neutral	0.002
NOTCH3	Q9UM47-1.2	A569H	Neutral	0.036
NOTCH3	Q9UM47-1.2	A569I	Neutral	0.008
NOTCH3	Q9UM47-1.2	A569K	Neutral	0.008
NOTCH3	Q9UM47-1.2	A569L	Neutral	0.008
NOTCH3	Q9UM47-1.2	A569M	Neutral	0.008
NOTCH3	Q9UM47-1.2	A569N	Neutral	0.04
NOTCH3	Q9UM47-1.2	A569P	Neutral	0.009
NOTCH3	Q9UM47-1.2	A569Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	A569R	Neutral	0.007
NOTCH3	Q9UM47-1.2	A569S	Neutral	0.0
NOTCH3	Q9UM47-1.2	A569T	Neutral	0.002
NOTCH3	Q9UM47-1.2	A569V	Neutral	0.002
NOTCH3	Q9UM47-1.2	A569W	Neutral	0.128
NOTCH3	Q9UM47-1.2	A569Y	Neutral	0.034
NOTCH3	Q9UM47-1.2	C570A	Pathogenic	0.505
NOTCH3	Q9UM47-1.2	C570D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C570E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C570F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	C570G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C570H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C570I	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	C570K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C570L	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	C570M	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C570N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C570P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C570Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C570R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C570S	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C570T	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C570V	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C570W	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	C570Y	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	A571C	Neutral	0.002
NOTCH3	Q9UM47-1.2	A571D	Neutral	0.04
NOTCH3	Q9UM47-1.2	A571E	Neutral	0.008
NOTCH3	Q9UM47-1.2	A571F	Neutral	0.034
NOTCH3	Q9UM47-1.2	A571G	Neutral	0.002
NOTCH3	Q9UM47-1.2	A571H	Neutral	0.036
NOTCH3	Q9UM47-1.2	A571I	Neutral	0.008
NOTCH3	Q9UM47-1.2	A571K	Neutral	0.008
NOTCH3	Q9UM47-1.2	A571L	Neutral	0.008
NOTCH3	Q9UM47-1.2	A571M	Neutral	0.008
NOTCH3	Q9UM47-1.2	A571N	Neutral	0.039
NOTCH3	Q9UM47-1.2	A571P	Neutral	0.009
NOTCH3	Q9UM47-1.2	A571Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	A571R	Neutral	0.007
NOTCH3	Q9UM47-1.2	A571S	Neutral	0.0
NOTCH3	Q9UM47-1.2	A571T	Neutral	0.002
NOTCH3	Q9UM47-1.2	A571V	Neutral	0.002
NOTCH3	Q9UM47-1.2	A571W	Neutral	0.126
NOTCH3	Q9UM47-1.2	A571Y	Neutral	0.033
NOTCH3	Q9UM47-1.2	P572A	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	P572C	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	P572D	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	P572E	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	P572F	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	P572G	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	P572H	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	P572I	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	P572K	Pathogenic	0.556
NOTCH3	Q9UM47-1.2	P572L	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	P572M	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	P572N	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	P572Q	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	P572R	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	P572S	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	P572T	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	P572V	Pathogenic	0.864
NOTCH3	Q9UM47-1.2	P572W	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	P572Y	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	G573A	Neutral	0.244
NOTCH3	Q9UM47-1.2	G573C	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	G573D	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	G573E	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	G573F	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G573H	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G573I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G573K	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	G573L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G573M	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G573N	Neutral	0.225
NOTCH3	Q9UM47-1.2	G573P	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	G573Q	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G573R	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	G573S	Neutral	0.24
NOTCH3	Q9UM47-1.2	G573T	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	G573V	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G573W	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	G573Y	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	Y574A	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	Y574C	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	Y574D	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	Y574E	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	Y574F	Neutral	0.026
NOTCH3	Q9UM47-1.2	Y574G	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	Y574H	Neutral	0.104
NOTCH3	Q9UM47-1.2	Y574I	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	Y574K	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	Y574L	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	Y574M	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	Y574N	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	Y574P	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	Y574Q	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	Y574R	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	Y574S	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	Y574T	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	Y574V	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	Y574W	Neutral	0.104
NOTCH3	Q9UM47-1.2	T575A	Neutral	0.176
NOTCH3	Q9UM47-1.2	T575C	Pathogenic	0.512
NOTCH3	Q9UM47-1.2	T575D	Pathogenic	0.518
NOTCH3	Q9UM47-1.2	T575E	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	T575F	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	T575G	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	T575H	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	T575I	Neutral	0.491
NOTCH3	Q9UM47-1.2	T575K	Neutral	0.48
NOTCH3	Q9UM47-1.2	T575L	Neutral	0.491
NOTCH3	Q9UM47-1.2	T575M	Neutral	0.49
NOTCH3	Q9UM47-1.2	T575N	Neutral	0.19
NOTCH3	Q9UM47-1.2	T575P	Pathogenic	0.515
NOTCH3	Q9UM47-1.2	T575Q	Neutral	0.498
NOTCH3	Q9UM47-1.2	T575R	Neutral	0.467
NOTCH3	Q9UM47-1.2	T575S	Neutral	0.046
NOTCH3	Q9UM47-1.2	T575V	Neutral	0.185
NOTCH3	Q9UM47-1.2	T575W	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	T575Y	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	G576A	Neutral	0.238
NOTCH3	Q9UM47-1.2	G576C	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	G576D	Pathogenic	0.565
NOTCH3	Q9UM47-1.2	G576E	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	G576F	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G576H	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	G576I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G576K	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	G576L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G576M	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G576N	Neutral	0.219
NOTCH3	Q9UM47-1.2	G576P	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	G576Q	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	G576R	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	G576S	Neutral	0.233
NOTCH3	Q9UM47-1.2	G576T	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	G576V	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	G576W	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	G576Y	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	T577A	Neutral	0.003
NOTCH3	Q9UM47-1.2	T577C	Neutral	0.013
NOTCH3	Q9UM47-1.2	T577D	Neutral	0.014
NOTCH3	Q9UM47-1.2	T577E	Neutral	0.013
NOTCH3	Q9UM47-1.2	T577F	Neutral	0.051
NOTCH3	Q9UM47-1.2	T577G	Neutral	0.05
NOTCH3	Q9UM47-1.2	T577H	Neutral	0.054
NOTCH3	Q9UM47-1.2	T577I	Neutral	0.012
NOTCH3	Q9UM47-1.2	T577K	Neutral	0.012
NOTCH3	Q9UM47-1.2	T577L	Neutral	0.012
NOTCH3	Q9UM47-1.2	T577M	Neutral	0.012
NOTCH3	Q9UM47-1.2	T577N	Neutral	0.003
NOTCH3	Q9UM47-1.2	T577P	Neutral	0.013
NOTCH3	Q9UM47-1.2	T577Q	Neutral	0.013
NOTCH3	Q9UM47-1.2	T577R	Neutral	0.011
NOTCH3	Q9UM47-1.2	T577S	Neutral	0.001
NOTCH3	Q9UM47-1.2	T577V	Neutral	0.003
NOTCH3	Q9UM47-1.2	T577W	Neutral	0.046
NOTCH3	Q9UM47-1.2	T577Y	Neutral	0.05
NOTCH3	Q9UM47-1.2	R578A	Neutral	0.122
NOTCH3	Q9UM47-1.2	R578C	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	R578D	Neutral	0.407
NOTCH3	Q9UM47-1.2	R578E	Neutral	0.034
NOTCH3	Q9UM47-1.2	R578F	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	R578G	Neutral	0.369
NOTCH3	Q9UM47-1.2	R578H	Neutral	0.036
NOTCH3	Q9UM47-1.2	R578I	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	R578K	Neutral	0.002
NOTCH3	Q9UM47-1.2	R578L	Neutral	0.443
NOTCH3	Q9UM47-1.2	R578M	Neutral	0.148
NOTCH3	Q9UM47-1.2	R578N	Neutral	0.033
NOTCH3	Q9UM47-1.2	R578P	Neutral	0.409
NOTCH3	Q9UM47-1.2	R578Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	R578S	Neutral	0.124
NOTCH3	Q9UM47-1.2	R578T	Neutral	0.133
NOTCH3	Q9UM47-1.2	R578V	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	R578W	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	R578Y	Neutral	0.458
NOTCH3	Q9UM47-1.2	C579A	Pathogenic	0.505
NOTCH3	Q9UM47-1.2	C579D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C579E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C579F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	C579G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C579H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C579I	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	C579K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C579L	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	C579M	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C579N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C579P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C579Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C579R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C579S	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C579T	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C579V	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C579W	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	C579Y	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	E580A	Neutral	0.244
NOTCH3	Q9UM47-1.2	E580C	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	E580D	Neutral	0.004
NOTCH3	Q9UM47-1.2	E580F	Pathogenic	0.878
NOTCH3	Q9UM47-1.2	E580G	Pathogenic	0.577
NOTCH3	Q9UM47-1.2	E580H	Neutral	0.075
NOTCH3	Q9UM47-1.2	E580I	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	E580K	Neutral	0.016
NOTCH3	Q9UM47-1.2	E580L	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	E580M	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	E580N	Neutral	0.073
NOTCH3	Q9UM47-1.2	E580P	Neutral	0.262
NOTCH3	Q9UM47-1.2	E580Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	E580R	Neutral	0.067
NOTCH3	Q9UM47-1.2	E580S	Neutral	0.068
NOTCH3	Q9UM47-1.2	E580T	Neutral	0.263
NOTCH3	Q9UM47-1.2	E580V	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	E580W	Pathogenic	0.867
NOTCH3	Q9UM47-1.2	E580Y	Pathogenic	0.606
NOTCH3	Q9UM47-1.2	S581A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S581C	Neutral	0.015
NOTCH3	Q9UM47-1.2	S581D	Neutral	0.003
NOTCH3	Q9UM47-1.2	S581E	Neutral	0.003
NOTCH3	Q9UM47-1.2	S581F	Neutral	0.055
NOTCH3	Q9UM47-1.2	S581G	Neutral	0.003
NOTCH3	Q9UM47-1.2	S581H	Neutral	0.013
NOTCH3	Q9UM47-1.2	S581I	Neutral	0.057
NOTCH3	Q9UM47-1.2	S581K	Neutral	0.003
NOTCH3	Q9UM47-1.2	S581L	Neutral	0.057
NOTCH3	Q9UM47-1.2	S581M	Neutral	0.013
NOTCH3	Q9UM47-1.2	S581N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S581P	Neutral	0.015
NOTCH3	Q9UM47-1.2	S581Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	S581R	Neutral	0.012
NOTCH3	Q9UM47-1.2	S581T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S581V	Neutral	0.061
NOTCH3	Q9UM47-1.2	S581W	Neutral	0.192
NOTCH3	Q9UM47-1.2	S581Y	Neutral	0.053
NOTCH3	Q9UM47-1.2	Q582A	Neutral	0.448
NOTCH3	Q9UM47-1.2	Q582C	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	Q582D	Neutral	0.164
NOTCH3	Q9UM47-1.2	Q582E	Neutral	0.01
NOTCH3	Q9UM47-1.2	Q582F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	Q582G	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	Q582H	Neutral	0.174
NOTCH3	Q9UM47-1.2	Q582I	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	Q582K	Neutral	0.042
NOTCH3	Q9UM47-1.2	Q582L	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	Q582M	Neutral	0.172
NOTCH3	Q9UM47-1.2	Q582N	Neutral	0.166
NOTCH3	Q9UM47-1.2	Q582P	Neutral	0.471
NOTCH3	Q9UM47-1.2	Q582R	Neutral	0.04
NOTCH3	Q9UM47-1.2	Q582S	Neutral	0.154
NOTCH3	Q9UM47-1.2	Q582T	Neutral	0.473
NOTCH3	Q9UM47-1.2	Q582V	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	Q582W	Pathogenic	0.788
NOTCH3	Q9UM47-1.2	Q582Y	Neutral	0.468
NOTCH3	Q9UM47-1.2	V583A	Neutral	0.032
NOTCH3	Q9UM47-1.2	V583C	Neutral	0.139
NOTCH3	Q9UM47-1.2	V583D	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	V583E	Neutral	0.442
NOTCH3	Q9UM47-1.2	V583F	Neutral	0.135
NOTCH3	Q9UM47-1.2	V583G	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	V583H	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	V583I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V583K	Neutral	0.418
NOTCH3	Q9UM47-1.2	V583L	Neutral	0.008
NOTCH3	Q9UM47-1.2	V583M	Neutral	0.008
NOTCH3	Q9UM47-1.2	V583N	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	V583P	Neutral	0.429
NOTCH3	Q9UM47-1.2	V583Q	Neutral	0.436
NOTCH3	Q9UM47-1.2	V583R	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	V583S	Neutral	0.414
NOTCH3	Q9UM47-1.2	V583T	Neutral	0.035
NOTCH3	Q9UM47-1.2	V583W	Pathogenic	0.744
NOTCH3	Q9UM47-1.2	V583Y	Neutral	0.132
NOTCH3	Q9UM47-1.2	D584A	Pathogenic	0.541
NOTCH3	Q9UM47-1.2	D584C	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	D584E	Neutral	0.003
NOTCH3	Q9UM47-1.2	D584F	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	D584G	Neutral	0.194
NOTCH3	Q9UM47-1.2	D584H	Neutral	0.204
NOTCH3	Q9UM47-1.2	D584I	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	D584K	Neutral	0.193
NOTCH3	Q9UM47-1.2	D584L	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	D584M	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	D584N	Neutral	0.013
NOTCH3	Q9UM47-1.2	D584P	Neutral	0.221
NOTCH3	Q9UM47-1.2	D584Q	Neutral	0.054
NOTCH3	Q9UM47-1.2	D584R	Pathogenic	0.508
NOTCH3	Q9UM47-1.2	D584S	Neutral	0.055
NOTCH3	Q9UM47-1.2	D584T	Neutral	0.22
NOTCH3	Q9UM47-1.2	D584V	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	D584W	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	D584Y	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	E585A	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	E585C	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	E585D	Neutral	0.046
NOTCH3	Q9UM47-1.2	E585F	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E585G	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	E585H	Pathogenic	0.511
NOTCH3	Q9UM47-1.2	E585I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	E585K	Neutral	0.176
NOTCH3	Q9UM47-1.2	E585L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	E585M	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	E585N	Pathogenic	0.506
NOTCH3	Q9UM47-1.2	E585P	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	E585Q	Neutral	0.049
NOTCH3	Q9UM47-1.2	E585R	Neutral	0.481
NOTCH3	Q9UM47-1.2	E585S	Neutral	0.485
NOTCH3	Q9UM47-1.2	E585T	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	E585V	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	E585W	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	E585Y	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C586A	Pathogenic	0.501
NOTCH3	Q9UM47-1.2	C586D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C586E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C586F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	C586G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C586H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C586I	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C586K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C586L	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C586M	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C586N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C586P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C586Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C586R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C586S	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C586T	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	C586V	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C586W	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	C586Y	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	R587A	Neutral	0.02
NOTCH3	Q9UM47-1.2	R587C	Neutral	0.313
NOTCH3	Q9UM47-1.2	R587D	Neutral	0.091
NOTCH3	Q9UM47-1.2	R587E	Neutral	0.005
NOTCH3	Q9UM47-1.2	R587F	Neutral	0.357
NOTCH3	Q9UM47-1.2	R587G	Neutral	0.079
NOTCH3	Q9UM47-1.2	R587H	Neutral	0.005
NOTCH3	Q9UM47-1.2	R587I	Neutral	0.347
NOTCH3	Q9UM47-1.2	R587K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R587L	Neutral	0.104
NOTCH3	Q9UM47-1.2	R587M	Neutral	0.025
NOTCH3	Q9UM47-1.2	R587N	Neutral	0.005
NOTCH3	Q9UM47-1.2	R587P	Neutral	0.092
NOTCH3	Q9UM47-1.2	R587Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	R587S	Neutral	0.02
NOTCH3	Q9UM47-1.2	R587T	Neutral	0.022
NOTCH3	Q9UM47-1.2	R587V	Neutral	0.33
NOTCH3	Q9UM47-1.2	R587W	Neutral	0.356
NOTCH3	Q9UM47-1.2	R587Y	Neutral	0.11
NOTCH3	Q9UM47-1.2	S588A	Neutral	0.109
NOTCH3	Q9UM47-1.2	S588C	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	S588D	Neutral	0.348
NOTCH3	Q9UM47-1.2	S588E	Neutral	0.332
NOTCH3	Q9UM47-1.2	S588F	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	S588G	Neutral	0.34
NOTCH3	Q9UM47-1.2	S588H	Pathogenic	0.685
NOTCH3	Q9UM47-1.2	S588I	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	S588K	Neutral	0.311
NOTCH3	Q9UM47-1.2	S588L	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	S588M	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	S588N	Neutral	0.103
NOTCH3	Q9UM47-1.2	S588P	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	S588Q	Neutral	0.327
NOTCH3	Q9UM47-1.2	S588R	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	S588T	Neutral	0.104
NOTCH3	Q9UM47-1.2	S588V	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	S588W	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	S588Y	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	Q589A	Neutral	0.282
NOTCH3	Q9UM47-1.2	Q589C	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	Q589D	Neutral	0.087
NOTCH3	Q9UM47-1.2	Q589E	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q589F	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	Q589G	Pathogenic	0.624
NOTCH3	Q9UM47-1.2	Q589H	Neutral	0.092
NOTCH3	Q9UM47-1.2	Q589I	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	Q589K	Neutral	0.021
NOTCH3	Q9UM47-1.2	Q589L	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	Q589M	Neutral	0.091
NOTCH3	Q9UM47-1.2	Q589N	Neutral	0.088
NOTCH3	Q9UM47-1.2	Q589P	Neutral	0.301
NOTCH3	Q9UM47-1.2	Q589R	Neutral	0.02
NOTCH3	Q9UM47-1.2	Q589S	Neutral	0.081
NOTCH3	Q9UM47-1.2	Q589T	Neutral	0.303
NOTCH3	Q9UM47-1.2	Q589V	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	Q589W	Pathogenic	0.644
NOTCH3	Q9UM47-1.2	Q589Y	Neutral	0.299
NOTCH3	Q9UM47-1.2	P590A	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	P590C	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	P590D	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	P590E	Pathogenic	0.702
NOTCH3	Q9UM47-1.2	P590F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P590G	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	P590H	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	P590I	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	P590K	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	P590L	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	P590M	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	P590N	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	P590Q	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	P590R	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	P590S	Pathogenic	0.702
NOTCH3	Q9UM47-1.2	P590T	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	P590V	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	P590W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P590Y	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	C591A	Pathogenic	0.502
NOTCH3	Q9UM47-1.2	C591D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C591E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C591F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	C591G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C591H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C591I	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C591K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C591L	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C591M	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C591N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C591P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C591Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C591R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C591S	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C591T	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	C591V	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C591W	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	C591Y	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	R592A	Neutral	0.159
NOTCH3	Q9UM47-1.2	R592C	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	R592D	Neutral	0.484
NOTCH3	Q9UM47-1.2	R592E	Neutral	0.046
NOTCH3	Q9UM47-1.2	R592F	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	R592G	Neutral	0.444
NOTCH3	Q9UM47-1.2	R592H	Neutral	0.048
NOTCH3	Q9UM47-1.2	R592I	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	R592K	Neutral	0.003
NOTCH3	Q9UM47-1.2	R592L	Pathogenic	0.521
NOTCH3	Q9UM47-1.2	R592M	Neutral	0.192
NOTCH3	Q9UM47-1.2	R592N	Neutral	0.044
NOTCH3	Q9UM47-1.2	R592P	Neutral	0.486
NOTCH3	Q9UM47-1.2	R592Q	Neutral	0.011
NOTCH3	Q9UM47-1.2	R592S	Neutral	0.162
NOTCH3	Q9UM47-1.2	R592T	Neutral	0.173
NOTCH3	Q9UM47-1.2	R592V	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	R592W	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	R592Y	Pathogenic	0.535
NOTCH3	Q9UM47-1.2	H593A	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	H593C	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	H593D	Neutral	0.393
NOTCH3	Q9UM47-1.2	H593E	Neutral	0.132
NOTCH3	Q9UM47-1.2	H593F	Neutral	0.403
NOTCH3	Q9UM47-1.2	H593G	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	H593I	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	H593K	Neutral	0.402
NOTCH3	Q9UM47-1.2	H593L	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	H593M	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	H593N	Neutral	0.031
NOTCH3	Q9UM47-1.2	H593P	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	H593Q	Neutral	0.134
NOTCH3	Q9UM47-1.2	H593R	Neutral	0.123
NOTCH3	Q9UM47-1.2	H593S	Neutral	0.375
NOTCH3	Q9UM47-1.2	H593T	Pathogenic	0.747
NOTCH3	Q9UM47-1.2	H593V	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	H593W	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	H593Y	Neutral	0.007
NOTCH3	Q9UM47-1.2	G594A	Neutral	0.042
NOTCH3	Q9UM47-1.2	G594C	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	G594D	Neutral	0.153
NOTCH3	Q9UM47-1.2	G594E	Neutral	0.435
NOTCH3	Q9UM47-1.2	G594F	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	G594H	Neutral	0.425
NOTCH3	Q9UM47-1.2	G594I	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	G594K	Neutral	0.411
NOTCH3	Q9UM47-1.2	G594L	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	G594M	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	G594N	Neutral	0.038
NOTCH3	Q9UM47-1.2	G594P	Neutral	0.453
NOTCH3	Q9UM47-1.2	G594Q	Neutral	0.429
NOTCH3	Q9UM47-1.2	G594R	Neutral	0.399
NOTCH3	Q9UM47-1.2	G594S	Neutral	0.041
NOTCH3	Q9UM47-1.2	G594T	Neutral	0.449
NOTCH3	Q9UM47-1.2	G594V	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	G594W	Neutral	0.388
NOTCH3	Q9UM47-1.2	G594Y	Pathogenic	0.756
NOTCH3	Q9UM47-1.2	G595A	Neutral	0.225
NOTCH3	Q9UM47-1.2	G595C	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	G595D	Pathogenic	0.547
NOTCH3	Q9UM47-1.2	G595E	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G595F	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G595H	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	G595I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G595K	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	G595L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G595M	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G595N	Neutral	0.207
NOTCH3	Q9UM47-1.2	G595P	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	G595Q	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	G595R	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	G595S	Neutral	0.221
NOTCH3	Q9UM47-1.2	G595T	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	G595V	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G595W	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	G595Y	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	K596A	Neutral	0.131
NOTCH3	Q9UM47-1.2	K596C	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	K596D	Neutral	0.141
NOTCH3	Q9UM47-1.2	K596E	Neutral	0.008
NOTCH3	Q9UM47-1.2	K596F	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	K596G	Neutral	0.39
NOTCH3	Q9UM47-1.2	K596H	Neutral	0.155
NOTCH3	Q9UM47-1.2	K596I	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	K596L	Neutral	0.465
NOTCH3	Q9UM47-1.2	K596M	Neutral	0.16
NOTCH3	Q9UM47-1.2	K596N	Neutral	0.036
NOTCH3	Q9UM47-1.2	K596P	Neutral	0.142
NOTCH3	Q9UM47-1.2	K596Q	Neutral	0.009
NOTCH3	Q9UM47-1.2	K596R	Neutral	0.002
NOTCH3	Q9UM47-1.2	K596S	Neutral	0.033
NOTCH3	Q9UM47-1.2	K596T	Neutral	0.143
NOTCH3	Q9UM47-1.2	K596V	Neutral	0.446
NOTCH3	Q9UM47-1.2	K596W	Pathogenic	0.788
NOTCH3	Q9UM47-1.2	K596Y	Neutral	0.468
NOTCH3	Q9UM47-1.2	C597A	Neutral	0.474
NOTCH3	Q9UM47-1.2	C597D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C597E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C597F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C597G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C597H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C597I	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	C597K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C597L	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	C597M	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	C597N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C597P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C597Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C597R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C597S	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C597T	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C597V	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C597W	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	C597Y	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	L598A	Neutral	0.016
NOTCH3	Q9UM47-1.2	L598C	Neutral	0.017
NOTCH3	Q9UM47-1.2	L598D	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	L598E	Neutral	0.28
NOTCH3	Q9UM47-1.2	L598F	Neutral	0.004
NOTCH3	Q9UM47-1.2	L598G	Pathogenic	0.582
NOTCH3	Q9UM47-1.2	L598H	Neutral	0.286
NOTCH3	Q9UM47-1.2	L598I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L598K	Neutral	0.08
NOTCH3	Q9UM47-1.2	L598M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L598N	Neutral	0.27
NOTCH3	Q9UM47-1.2	L598P	Neutral	0.263
NOTCH3	Q9UM47-1.2	L598Q	Neutral	0.08
NOTCH3	Q9UM47-1.2	L598R	Neutral	0.076
NOTCH3	Q9UM47-1.2	L598S	Neutral	0.069
NOTCH3	Q9UM47-1.2	L598T	Neutral	0.017
NOTCH3	Q9UM47-1.2	L598V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L598W	Neutral	0.071
NOTCH3	Q9UM47-1.2	L598Y	Neutral	0.018
NOTCH3	Q9UM47-1.2	D599A	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	D599C	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D599E	Neutral	0.029
NOTCH3	Q9UM47-1.2	D599F	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D599G	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	D599H	Pathogenic	0.736
NOTCH3	Q9UM47-1.2	D599I	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D599K	Pathogenic	0.721
NOTCH3	Q9UM47-1.2	D599L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D599M	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D599N	Neutral	0.127
NOTCH3	Q9UM47-1.2	D599P	Pathogenic	0.755
NOTCH3	Q9UM47-1.2	D599Q	Neutral	0.382
NOTCH3	Q9UM47-1.2	D599R	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	D599S	Neutral	0.387
NOTCH3	Q9UM47-1.2	D599T	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	D599V	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D599W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D599Y	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L600A	Neutral	0.246
NOTCH3	Q9UM47-1.2	L600C	Neutral	0.259
NOTCH3	Q9UM47-1.2	L600D	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	L600E	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	L600F	Neutral	0.078
NOTCH3	Q9UM47-1.2	L600G	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	L600H	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	L600I	Neutral	0.004
NOTCH3	Q9UM47-1.2	L600K	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	L600M	Neutral	0.004
NOTCH3	Q9UM47-1.2	L600N	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	L600P	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	L600Q	Pathogenic	0.641
NOTCH3	Q9UM47-1.2	L600R	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	L600S	Pathogenic	0.604
NOTCH3	Q9UM47-1.2	L600T	Neutral	0.265
NOTCH3	Q9UM47-1.2	L600V	Neutral	0.018
NOTCH3	Q9UM47-1.2	L600W	Pathogenic	0.612
NOTCH3	Q9UM47-1.2	L600Y	Neutral	0.275
NOTCH3	Q9UM47-1.2	V601A	Neutral	0.092
NOTCH3	Q9UM47-1.2	V601C	Neutral	0.33
NOTCH3	Q9UM47-1.2	V601D	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	V601E	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	V601F	Neutral	0.321
NOTCH3	Q9UM47-1.2	V601G	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	V601H	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	V601I	Neutral	0.001
NOTCH3	Q9UM47-1.2	V601K	Pathogenic	0.686
NOTCH3	Q9UM47-1.2	V601L	Neutral	0.023
NOTCH3	Q9UM47-1.2	V601M	Neutral	0.023
NOTCH3	Q9UM47-1.2	V601N	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	V601P	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	V601Q	Pathogenic	0.702
NOTCH3	Q9UM47-1.2	V601R	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	V601S	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	V601T	Neutral	0.101
NOTCH3	Q9UM47-1.2	V601W	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	V601Y	Neutral	0.316
NOTCH3	Q9UM47-1.2	D602A	Neutral	0.214
NOTCH3	Q9UM47-1.2	D602C	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	D602E	Neutral	0.001
NOTCH3	Q9UM47-1.2	D602F	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	D602G	Neutral	0.053
NOTCH3	Q9UM47-1.2	D602H	Neutral	0.056
NOTCH3	Q9UM47-1.2	D602I	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	D602K	Neutral	0.052
NOTCH3	Q9UM47-1.2	D602L	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	D602M	Pathogenic	0.547
NOTCH3	Q9UM47-1.2	D602N	Neutral	0.003
NOTCH3	Q9UM47-1.2	D602P	Neutral	0.062
NOTCH3	Q9UM47-1.2	D602Q	Neutral	0.013
NOTCH3	Q9UM47-1.2	D602R	Neutral	0.193
NOTCH3	Q9UM47-1.2	D602S	Neutral	0.013
NOTCH3	Q9UM47-1.2	D602T	Neutral	0.061
NOTCH3	Q9UM47-1.2	D602V	Pathogenic	0.565
NOTCH3	Q9UM47-1.2	D602W	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	D602Y	Pathogenic	0.53
NOTCH3	Q9UM47-1.2	K603A	Neutral	0.124
NOTCH3	Q9UM47-1.2	K603C	Pathogenic	0.761
NOTCH3	Q9UM47-1.2	K603D	Neutral	0.134
NOTCH3	Q9UM47-1.2	K603E	Neutral	0.008
NOTCH3	Q9UM47-1.2	K603F	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	K603G	Neutral	0.374
NOTCH3	Q9UM47-1.2	K603H	Neutral	0.147
NOTCH3	Q9UM47-1.2	K603I	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	K603L	Neutral	0.449
NOTCH3	Q9UM47-1.2	K603M	Neutral	0.151
NOTCH3	Q9UM47-1.2	K603N	Neutral	0.033
NOTCH3	Q9UM47-1.2	K603P	Neutral	0.135
NOTCH3	Q9UM47-1.2	K603Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	K603R	Neutral	0.002
NOTCH3	Q9UM47-1.2	K603S	Neutral	0.031
NOTCH3	Q9UM47-1.2	K603T	Neutral	0.135
NOTCH3	Q9UM47-1.2	K603V	Neutral	0.43
NOTCH3	Q9UM47-1.2	K603W	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	K603Y	Neutral	0.452
NOTCH3	Q9UM47-1.2	Y604A	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	Y604C	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	Y604D	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	Y604E	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	Y604F	Neutral	0.038
NOTCH3	Q9UM47-1.2	Y604G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	Y604H	Neutral	0.144
NOTCH3	Q9UM47-1.2	Y604I	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	Y604K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	Y604L	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	Y604M	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	Y604N	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	Y604P	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	Y604Q	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	Y604R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	Y604S	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	Y604T	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	Y604V	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	Y604W	Neutral	0.144
NOTCH3	Q9UM47-1.2	L605A	Neutral	0.056
NOTCH3	Q9UM47-1.2	L605C	Neutral	0.059
NOTCH3	Q9UM47-1.2	L605D	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	L605E	Pathogenic	0.592
NOTCH3	Q9UM47-1.2	L605F	Neutral	0.015
NOTCH3	Q9UM47-1.2	L605G	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	L605H	Pathogenic	0.599
NOTCH3	Q9UM47-1.2	L605I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L605K	Neutral	0.245
NOTCH3	Q9UM47-1.2	L605M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L605N	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	L605P	Pathogenic	0.571
NOTCH3	Q9UM47-1.2	L605Q	Neutral	0.245
NOTCH3	Q9UM47-1.2	L605R	Neutral	0.236
NOTCH3	Q9UM47-1.2	L605S	Neutral	0.216
NOTCH3	Q9UM47-1.2	L605T	Neutral	0.061
NOTCH3	Q9UM47-1.2	L605V	Neutral	0.003
NOTCH3	Q9UM47-1.2	L605W	Neutral	0.222
NOTCH3	Q9UM47-1.2	L605Y	Neutral	0.064
NOTCH3	Q9UM47-1.2	C606A	Neutral	0.498
NOTCH3	Q9UM47-1.2	C606D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C606E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C606F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	C606G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C606H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C606I	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C606K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C606L	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C606M	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C606N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C606P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C606Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C606R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C606S	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C606T	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C606V	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C606W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C606Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	R607A	Neutral	0.021
NOTCH3	Q9UM47-1.2	R607C	Neutral	0.323
NOTCH3	Q9UM47-1.2	R607D	Neutral	0.095
NOTCH3	Q9UM47-1.2	R607E	Neutral	0.005
NOTCH3	Q9UM47-1.2	R607F	Neutral	0.367
NOTCH3	Q9UM47-1.2	R607G	Neutral	0.082
NOTCH3	Q9UM47-1.2	R607H	Neutral	0.006
NOTCH3	Q9UM47-1.2	R607I	Neutral	0.357
NOTCH3	Q9UM47-1.2	R607K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R607L	Neutral	0.109
NOTCH3	Q9UM47-1.2	R607M	Neutral	0.026
NOTCH3	Q9UM47-1.2	R607N	Neutral	0.005
NOTCH3	Q9UM47-1.2	R607P	Neutral	0.096
NOTCH3	Q9UM47-1.2	R607Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	R607S	Neutral	0.021
NOTCH3	Q9UM47-1.2	R607T	Neutral	0.023
NOTCH3	Q9UM47-1.2	R607V	Neutral	0.339
NOTCH3	Q9UM47-1.2	R607W	Neutral	0.366
NOTCH3	Q9UM47-1.2	R607Y	Neutral	0.114
NOTCH3	Q9UM47-1.2	C608A	Neutral	0.488
NOTCH3	Q9UM47-1.2	C608D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C608E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C608F	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	C608G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C608H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C608I	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C608K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C608L	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C608M	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	C608N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C608P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C608Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C608R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C608S	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	C608T	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C608V	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	C608W	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	C608Y	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	P609A	Neutral	0.062
NOTCH3	Q9UM47-1.2	P609C	Pathogenic	0.595
NOTCH3	Q9UM47-1.2	P609D	Neutral	0.067
NOTCH3	Q9UM47-1.2	P609E	Neutral	0.063
NOTCH3	Q9UM47-1.2	P609F	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	P609G	Neutral	0.218
NOTCH3	Q9UM47-1.2	P609H	Neutral	0.227
NOTCH3	Q9UM47-1.2	P609I	Pathogenic	0.568
NOTCH3	Q9UM47-1.2	P609K	Neutral	0.058
NOTCH3	Q9UM47-1.2	P609L	Pathogenic	0.568
NOTCH3	Q9UM47-1.2	P609M	Neutral	0.223
NOTCH3	Q9UM47-1.2	P609N	Neutral	0.244
NOTCH3	Q9UM47-1.2	P609Q	Neutral	0.062
NOTCH3	Q9UM47-1.2	P609R	Neutral	0.209
NOTCH3	Q9UM47-1.2	P609S	Neutral	0.063
NOTCH3	Q9UM47-1.2	P609T	Neutral	0.066
NOTCH3	Q9UM47-1.2	P609V	Neutral	0.236
NOTCH3	Q9UM47-1.2	P609W	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	P609Y	Pathogenic	0.55
NOTCH3	Q9UM47-1.2	S610A	Neutral	0.0
NOTCH3	Q9UM47-1.2	S610C	Neutral	0.002
NOTCH3	Q9UM47-1.2	S610D	Neutral	0.0
NOTCH3	Q9UM47-1.2	S610E	Neutral	0.0
NOTCH3	Q9UM47-1.2	S610F	Neutral	0.008
NOTCH3	Q9UM47-1.2	S610G	Neutral	0.0
NOTCH3	Q9UM47-1.2	S610H	Neutral	0.002
NOTCH3	Q9UM47-1.2	S610I	Neutral	0.009
NOTCH3	Q9UM47-1.2	S610K	Neutral	0.0
NOTCH3	Q9UM47-1.2	S610L	Neutral	0.009
NOTCH3	Q9UM47-1.2	S610M	Neutral	0.002
NOTCH3	Q9UM47-1.2	S610N	Neutral	0.0
NOTCH3	Q9UM47-1.2	S610P	Neutral	0.002
NOTCH3	Q9UM47-1.2	S610Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	S610R	Neutral	0.002
NOTCH3	Q9UM47-1.2	S610T	Neutral	0.0
NOTCH3	Q9UM47-1.2	S610V	Neutral	0.009
NOTCH3	Q9UM47-1.2	S610W	Neutral	0.034
NOTCH3	Q9UM47-1.2	S610Y	Neutral	0.008
NOTCH3	Q9UM47-1.2	G611A	Neutral	0.226
NOTCH3	Q9UM47-1.2	G611C	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G611D	Pathogenic	0.549
NOTCH3	Q9UM47-1.2	G611E	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	G611F	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G611H	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	G611I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G611K	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G611L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G611M	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G611N	Neutral	0.208
NOTCH3	Q9UM47-1.2	G611P	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G611Q	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G611R	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	G611S	Neutral	0.222
NOTCH3	Q9UM47-1.2	G611T	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G611V	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G611W	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	G611Y	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	T612A	Neutral	0.409
NOTCH3	Q9UM47-1.2	T612C	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	T612D	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	T612E	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	T612F	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	T612G	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	T612H	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	T612I	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	T612K	Pathogenic	0.75
NOTCH3	Q9UM47-1.2	T612L	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	T612M	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	T612N	Neutral	0.433
NOTCH3	Q9UM47-1.2	T612P	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	T612Q	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	T612R	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	T612S	Neutral	0.135
NOTCH3	Q9UM47-1.2	T612V	Neutral	0.424
NOTCH3	Q9UM47-1.2	T612W	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	T612Y	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	T613A	Neutral	0.061
NOTCH3	Q9UM47-1.2	T613C	Neutral	0.241
NOTCH3	Q9UM47-1.2	T613D	Neutral	0.245
NOTCH3	Q9UM47-1.2	T613E	Neutral	0.235
NOTCH3	Q9UM47-1.2	T613F	Pathogenic	0.56
NOTCH3	Q9UM47-1.2	T613G	Pathogenic	0.555
NOTCH3	Q9UM47-1.2	T613H	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	T613I	Neutral	0.226
NOTCH3	Q9UM47-1.2	T613K	Neutral	0.218
NOTCH3	Q9UM47-1.2	T613L	Neutral	0.226
NOTCH3	Q9UM47-1.2	T613M	Neutral	0.225
NOTCH3	Q9UM47-1.2	T613N	Neutral	0.066
NOTCH3	Q9UM47-1.2	T613P	Neutral	0.244
NOTCH3	Q9UM47-1.2	T613Q	Neutral	0.231
NOTCH3	Q9UM47-1.2	T613R	Neutral	0.21
NOTCH3	Q9UM47-1.2	T613S	Neutral	0.014
NOTCH3	Q9UM47-1.2	T613V	Neutral	0.064
NOTCH3	Q9UM47-1.2	T613W	Pathogenic	0.535
NOTCH3	Q9UM47-1.2	T613Y	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	G614A	Neutral	0.221
NOTCH3	Q9UM47-1.2	G614C	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G614D	Pathogenic	0.541
NOTCH3	Q9UM47-1.2	G614E	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	G614F	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G614H	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	G614I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G614K	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	G614L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G614M	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G614N	Neutral	0.202
NOTCH3	Q9UM47-1.2	G614P	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	G614Q	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	G614R	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	G614S	Neutral	0.216
NOTCH3	Q9UM47-1.2	G614T	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	G614V	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G614W	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	G614Y	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	V615A	Neutral	0.039
NOTCH3	Q9UM47-1.2	V615C	Neutral	0.164
NOTCH3	Q9UM47-1.2	V615D	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	V615E	Neutral	0.49
NOTCH3	Q9UM47-1.2	V615F	Neutral	0.159
NOTCH3	Q9UM47-1.2	V615G	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	V615H	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	V615I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V615K	Neutral	0.466
NOTCH3	Q9UM47-1.2	V615L	Neutral	0.009
NOTCH3	Q9UM47-1.2	V615M	Neutral	0.009
NOTCH3	Q9UM47-1.2	V615N	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	V615P	Neutral	0.477
NOTCH3	Q9UM47-1.2	V615Q	Neutral	0.484
NOTCH3	Q9UM47-1.2	V615R	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	V615S	Neutral	0.462
NOTCH3	Q9UM47-1.2	V615T	Neutral	0.043
NOTCH3	Q9UM47-1.2	V615W	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	V615Y	Neutral	0.155
NOTCH3	Q9UM47-1.2	N616A	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	N616C	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	N616D	Neutral	0.114
NOTCH3	Q9UM47-1.2	N616E	Neutral	0.363
NOTCH3	Q9UM47-1.2	N616F	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	N616G	Neutral	0.333
NOTCH3	Q9UM47-1.2	N616H	Neutral	0.108
NOTCH3	Q9UM47-1.2	N616I	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	N616K	Neutral	0.34
NOTCH3	Q9UM47-1.2	N616L	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	N616M	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	N616P	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	N616Q	Neutral	0.359
NOTCH3	Q9UM47-1.2	N616R	Neutral	0.329
NOTCH3	Q9UM47-1.2	N616S	Neutral	0.108
NOTCH3	Q9UM47-1.2	N616T	Neutral	0.373
NOTCH3	Q9UM47-1.2	N616V	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	N616W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	N616Y	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	C617A	Neutral	0.491
NOTCH3	Q9UM47-1.2	C617D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C617E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C617F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C617G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C617H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C617I	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C617K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C617L	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C617M	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C617N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C617P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C617Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C617R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C617S	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C617T	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	C617V	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C617W	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	C617Y	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	E618A	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	E618C	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	E618D	Neutral	0.04
NOTCH3	Q9UM47-1.2	E618F	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	E618G	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	E618H	Neutral	0.474
NOTCH3	Q9UM47-1.2	E618I	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	E618K	Neutral	0.156
NOTCH3	Q9UM47-1.2	E618L	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	E618M	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	E618N	Neutral	0.469
NOTCH3	Q9UM47-1.2	E618P	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	E618Q	Neutral	0.042
NOTCH3	Q9UM47-1.2	E618R	Neutral	0.444
NOTCH3	Q9UM47-1.2	E618S	Neutral	0.448
NOTCH3	Q9UM47-1.2	E618T	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	E618V	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	E618W	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	E618Y	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	V619A	Neutral	0.025
NOTCH3	Q9UM47-1.2	V619C	Neutral	0.113
NOTCH3	Q9UM47-1.2	V619D	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	V619E	Neutral	0.383
NOTCH3	Q9UM47-1.2	V619F	Neutral	0.109
NOTCH3	Q9UM47-1.2	V619G	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	V619H	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	V619I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V619K	Neutral	0.36
NOTCH3	Q9UM47-1.2	V619L	Neutral	0.006
NOTCH3	Q9UM47-1.2	V619M	Neutral	0.006
NOTCH3	Q9UM47-1.2	V619N	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	V619P	Neutral	0.37
NOTCH3	Q9UM47-1.2	V619Q	Neutral	0.377
NOTCH3	Q9UM47-1.2	V619R	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	V619S	Neutral	0.356
NOTCH3	Q9UM47-1.2	V619T	Neutral	0.028
NOTCH3	Q9UM47-1.2	V619W	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	V619Y	Neutral	0.106
NOTCH3	Q9UM47-1.2	N620A	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	N620C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N620D	Neutral	0.137
NOTCH3	Q9UM47-1.2	N620E	Neutral	0.411
NOTCH3	Q9UM47-1.2	N620F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N620G	Neutral	0.38
NOTCH3	Q9UM47-1.2	N620H	Neutral	0.13
NOTCH3	Q9UM47-1.2	N620I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N620K	Neutral	0.387
NOTCH3	Q9UM47-1.2	N620L	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N620M	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	N620P	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	N620Q	Neutral	0.407
NOTCH3	Q9UM47-1.2	N620R	Neutral	0.376
NOTCH3	Q9UM47-1.2	N620S	Neutral	0.129
NOTCH3	Q9UM47-1.2	N620T	Neutral	0.422
NOTCH3	Q9UM47-1.2	N620V	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N620W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N620Y	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	I621A	Neutral	0.077
NOTCH3	Q9UM47-1.2	I621C	Neutral	0.082
NOTCH3	Q9UM47-1.2	I621D	Pathogenic	0.656
NOTCH3	Q9UM47-1.2	I621E	Pathogenic	0.672
NOTCH3	Q9UM47-1.2	I621F	Neutral	0.021
NOTCH3	Q9UM47-1.2	I621G	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	I621H	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	I621K	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	I621L	Neutral	0.001
NOTCH3	Q9UM47-1.2	I621M	Neutral	0.005
NOTCH3	Q9UM47-1.2	I621N	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	I621P	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	I621Q	Pathogenic	0.675
NOTCH3	Q9UM47-1.2	I621R	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	I621S	Neutral	0.28
NOTCH3	Q9UM47-1.2	I621T	Neutral	0.084
NOTCH3	Q9UM47-1.2	I621V	Neutral	0.0
NOTCH3	Q9UM47-1.2	I621W	Pathogenic	0.647
NOTCH3	Q9UM47-1.2	I621Y	Neutral	0.088
NOTCH3	Q9UM47-1.2	D622A	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	D622C	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	D622E	Neutral	0.019
NOTCH3	Q9UM47-1.2	D622F	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	D622G	Pathogenic	0.626
NOTCH3	Q9UM47-1.2	D622H	Pathogenic	0.641
NOTCH3	Q9UM47-1.2	D622I	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	D622K	Pathogenic	0.624
NOTCH3	Q9UM47-1.2	D622L	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	D622M	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	D622N	Neutral	0.085
NOTCH3	Q9UM47-1.2	D622P	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	D622Q	Neutral	0.284
NOTCH3	Q9UM47-1.2	D622R	Pathogenic	0.878
NOTCH3	Q9UM47-1.2	D622S	Neutral	0.289
NOTCH3	Q9UM47-1.2	D622T	Pathogenic	0.663
NOTCH3	Q9UM47-1.2	D622V	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	D622W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	D622Y	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	D623A	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	D623C	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	D623E	Neutral	0.019
NOTCH3	Q9UM47-1.2	D623F	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	D623G	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	D623H	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	D623I	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	D623K	Pathogenic	0.625
NOTCH3	Q9UM47-1.2	D623L	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	D623M	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	D623N	Neutral	0.085
NOTCH3	Q9UM47-1.2	D623P	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	D623Q	Neutral	0.285
NOTCH3	Q9UM47-1.2	D623R	Pathogenic	0.878
NOTCH3	Q9UM47-1.2	D623S	Neutral	0.289
NOTCH3	Q9UM47-1.2	D623T	Pathogenic	0.664
NOTCH3	Q9UM47-1.2	D623V	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	D623W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	D623Y	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	C624A	Neutral	0.5
NOTCH3	Q9UM47-1.2	C624D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C624E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C624F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	C624G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C624H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C624I	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C624K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C624L	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C624M	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C624N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C624P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C624Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C624R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C624S	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	C624T	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	C624V	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C624W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C624Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	A625C	Neutral	0.112
NOTCH3	Q9UM47-1.2	A625D	Pathogenic	0.72
NOTCH3	Q9UM47-1.2	A625E	Neutral	0.345
NOTCH3	Q9UM47-1.2	A625F	Pathogenic	0.685
NOTCH3	Q9UM47-1.2	A625G	Neutral	0.112
NOTCH3	Q9UM47-1.2	A625H	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	A625I	Neutral	0.333
NOTCH3	Q9UM47-1.2	A625K	Neutral	0.323
NOTCH3	Q9UM47-1.2	A625L	Neutral	0.333
NOTCH3	Q9UM47-1.2	A625M	Neutral	0.332
NOTCH3	Q9UM47-1.2	A625N	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	A625P	Neutral	0.361
NOTCH3	Q9UM47-1.2	A625Q	Neutral	0.34
NOTCH3	Q9UM47-1.2	A625R	Neutral	0.312
NOTCH3	Q9UM47-1.2	A625S	Neutral	0.028
NOTCH3	Q9UM47-1.2	A625T	Neutral	0.109
NOTCH3	Q9UM47-1.2	A625V	Neutral	0.105
NOTCH3	Q9UM47-1.2	A625W	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	A625Y	Pathogenic	0.679
NOTCH3	Q9UM47-1.2	S626A	Neutral	0.084
NOTCH3	Q9UM47-1.2	S626C	Pathogenic	0.65
NOTCH3	Q9UM47-1.2	S626D	Neutral	0.285
NOTCH3	Q9UM47-1.2	S626E	Neutral	0.271
NOTCH3	Q9UM47-1.2	S626F	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	S626G	Neutral	0.279
NOTCH3	Q9UM47-1.2	S626H	Pathogenic	0.62
NOTCH3	Q9UM47-1.2	S626I	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	S626K	Neutral	0.252
NOTCH3	Q9UM47-1.2	S626L	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	S626M	Pathogenic	0.617
NOTCH3	Q9UM47-1.2	S626N	Neutral	0.079
NOTCH3	Q9UM47-1.2	S626P	Pathogenic	0.646
NOTCH3	Q9UM47-1.2	S626Q	Neutral	0.267
NOTCH3	Q9UM47-1.2	S626R	Pathogenic	0.594
NOTCH3	Q9UM47-1.2	S626T	Neutral	0.08
NOTCH3	Q9UM47-1.2	S626V	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	S626W	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	S626Y	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	N627A	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	N627C	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	N627D	Neutral	0.048
NOTCH3	Q9UM47-1.2	N627E	Neutral	0.181
NOTCH3	Q9UM47-1.2	N627F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	N627G	Neutral	0.162
NOTCH3	Q9UM47-1.2	N627H	Neutral	0.045
NOTCH3	Q9UM47-1.2	N627I	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	N627K	Neutral	0.167
NOTCH3	Q9UM47-1.2	N627L	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	N627M	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	N627P	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	N627Q	Neutral	0.178
NOTCH3	Q9UM47-1.2	N627R	Neutral	0.16
NOTCH3	Q9UM47-1.2	N627S	Neutral	0.045
NOTCH3	Q9UM47-1.2	N627T	Neutral	0.187
NOTCH3	Q9UM47-1.2	N627V	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	N627W	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	N627Y	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	P628A	Pathogenic	0.639
NOTCH3	Q9UM47-1.2	P628C	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	P628D	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	P628E	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	P628F	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P628G	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	P628H	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	P628I	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	P628K	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	P628L	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	P628M	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	P628N	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	P628Q	Pathogenic	0.639
NOTCH3	Q9UM47-1.2	P628R	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	P628S	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	P628T	Pathogenic	0.657
NOTCH3	Q9UM47-1.2	P628V	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	P628W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	P628Y	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	C629A	Neutral	0.5
NOTCH3	Q9UM47-1.2	C629D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C629E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C629F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	C629G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C629H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C629I	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C629K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C629L	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C629M	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C629N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C629P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C629Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C629R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C629S	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	C629T	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	C629V	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C629W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C629Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	T630A	Neutral	0.003
NOTCH3	Q9UM47-1.2	T630C	Neutral	0.016
NOTCH3	Q9UM47-1.2	T630D	Neutral	0.017
NOTCH3	Q9UM47-1.2	T630E	Neutral	0.016
NOTCH3	Q9UM47-1.2	T630F	Neutral	0.062
NOTCH3	Q9UM47-1.2	T630G	Neutral	0.06
NOTCH3	Q9UM47-1.2	T630H	Neutral	0.065
NOTCH3	Q9UM47-1.2	T630I	Neutral	0.015
NOTCH3	Q9UM47-1.2	T630K	Neutral	0.014
NOTCH3	Q9UM47-1.2	T630L	Neutral	0.015
NOTCH3	Q9UM47-1.2	T630M	Neutral	0.015
NOTCH3	Q9UM47-1.2	T630N	Neutral	0.004
NOTCH3	Q9UM47-1.2	T630P	Neutral	0.016
NOTCH3	Q9UM47-1.2	T630Q	Neutral	0.015
NOTCH3	Q9UM47-1.2	T630R	Neutral	0.014
NOTCH3	Q9UM47-1.2	T630S	Neutral	0.001
NOTCH3	Q9UM47-1.2	T630V	Neutral	0.004
NOTCH3	Q9UM47-1.2	T630W	Neutral	0.056
NOTCH3	Q9UM47-1.2	T630Y	Neutral	0.06
NOTCH3	Q9UM47-1.2	F631A	Neutral	0.291
NOTCH3	Q9UM47-1.2	F631C	Neutral	0.305
NOTCH3	Q9UM47-1.2	F631D	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	F631E	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	F631G	Pathogenic	0.635
NOTCH3	Q9UM47-1.2	F631H	Neutral	0.099
NOTCH3	Q9UM47-1.2	F631I	Neutral	0.024
NOTCH3	Q9UM47-1.2	F631K	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	F631L	Neutral	0.024
NOTCH3	Q9UM47-1.2	F631M	Neutral	0.024
NOTCH3	Q9UM47-1.2	F631N	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	F631P	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	F631Q	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	F631R	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	F631S	Neutral	0.296
NOTCH3	Q9UM47-1.2	F631T	Neutral	0.312
NOTCH3	Q9UM47-1.2	F631V	Neutral	0.094
NOTCH3	Q9UM47-1.2	F631W	Neutral	0.005
NOTCH3	Q9UM47-1.2	F631Y	Neutral	0.0
NOTCH3	Q9UM47-1.2	G632A	Neutral	0.219
NOTCH3	Q9UM47-1.2	G632C	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G632D	Pathogenic	0.539
NOTCH3	Q9UM47-1.2	G632E	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	G632F	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G632H	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	G632I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G632K	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	G632L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G632M	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G632N	Neutral	0.201
NOTCH3	Q9UM47-1.2	G632P	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	G632Q	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G632R	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	G632S	Neutral	0.215
NOTCH3	Q9UM47-1.2	G632T	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	G632V	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G632W	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	G632Y	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	V633A	Neutral	0.012
NOTCH3	Q9UM47-1.2	V633C	Neutral	0.054
NOTCH3	Q9UM47-1.2	V633D	Pathogenic	0.552
NOTCH3	Q9UM47-1.2	V633E	Neutral	0.219
NOTCH3	Q9UM47-1.2	V633F	Neutral	0.052
NOTCH3	Q9UM47-1.2	V633G	Pathogenic	0.509
NOTCH3	Q9UM47-1.2	V633H	Pathogenic	0.551
NOTCH3	Q9UM47-1.2	V633I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V633K	Neutral	0.203
NOTCH3	Q9UM47-1.2	V633L	Neutral	0.003
NOTCH3	Q9UM47-1.2	V633M	Neutral	0.003
NOTCH3	Q9UM47-1.2	V633N	Pathogenic	0.556
NOTCH3	Q9UM47-1.2	V633P	Neutral	0.21
NOTCH3	Q9UM47-1.2	V633Q	Neutral	0.215
NOTCH3	Q9UM47-1.2	V633R	Pathogenic	0.524
NOTCH3	Q9UM47-1.2	V633S	Neutral	0.2
NOTCH3	Q9UM47-1.2	V633T	Neutral	0.013
NOTCH3	Q9UM47-1.2	V633W	Pathogenic	0.507
NOTCH3	Q9UM47-1.2	V633Y	Neutral	0.051
NOTCH3	Q9UM47-1.2	C634A	Neutral	0.5
NOTCH3	Q9UM47-1.2	C634D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C634E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C634F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	C634G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C634H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C634I	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C634K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C634L	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C634M	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C634N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C634P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C634Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C634R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C634S	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	C634T	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	C634V	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C634W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C634Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	R635A	Neutral	0.024
NOTCH3	Q9UM47-1.2	R635C	Neutral	0.36
NOTCH3	Q9UM47-1.2	R635D	Neutral	0.111
NOTCH3	Q9UM47-1.2	R635E	Neutral	0.006
NOTCH3	Q9UM47-1.2	R635F	Neutral	0.406
NOTCH3	Q9UM47-1.2	R635G	Neutral	0.096
NOTCH3	Q9UM47-1.2	R635H	Neutral	0.007
NOTCH3	Q9UM47-1.2	R635I	Neutral	0.396
NOTCH3	Q9UM47-1.2	R635K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R635L	Neutral	0.126
NOTCH3	Q9UM47-1.2	R635M	Neutral	0.031
NOTCH3	Q9UM47-1.2	R635N	Neutral	0.006
NOTCH3	Q9UM47-1.2	R635P	Neutral	0.111
NOTCH3	Q9UM47-1.2	R635Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	R635S	Neutral	0.025
NOTCH3	Q9UM47-1.2	R635T	Neutral	0.027
NOTCH3	Q9UM47-1.2	R635V	Neutral	0.378
NOTCH3	Q9UM47-1.2	R635W	Neutral	0.405
NOTCH3	Q9UM47-1.2	R635Y	Neutral	0.133
NOTCH3	Q9UM47-1.2	D636A	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	D636C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D636E	Neutral	0.033
NOTCH3	Q9UM47-1.2	D636F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D636G	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	D636H	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	D636I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D636K	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	D636L	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	D636M	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D636N	Neutral	0.142
NOTCH3	Q9UM47-1.2	D636P	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	D636Q	Neutral	0.413
NOTCH3	Q9UM47-1.2	D636R	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	D636S	Neutral	0.418
NOTCH3	Q9UM47-1.2	D636T	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	D636V	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D636W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D636Y	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	G637A	Neutral	0.052
NOTCH3	Q9UM47-1.2	G637C	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	G637D	Neutral	0.185
NOTCH3	Q9UM47-1.2	G637E	Neutral	0.491
NOTCH3	Q9UM47-1.2	G637F	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	G637H	Neutral	0.481
NOTCH3	Q9UM47-1.2	G637I	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	G637K	Neutral	0.467
NOTCH3	Q9UM47-1.2	G637L	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	G637M	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	G637N	Neutral	0.047
NOTCH3	Q9UM47-1.2	G637P	Pathogenic	0.509
NOTCH3	Q9UM47-1.2	G637Q	Neutral	0.485
NOTCH3	Q9UM47-1.2	G637R	Neutral	0.454
NOTCH3	Q9UM47-1.2	G637S	Neutral	0.051
NOTCH3	Q9UM47-1.2	G637T	Pathogenic	0.506
NOTCH3	Q9UM47-1.2	G637V	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	G637W	Neutral	0.442
NOTCH3	Q9UM47-1.2	G637Y	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	I638A	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	I638C	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	I638D	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	I638E	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I638F	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	I638G	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	I638H	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I638K	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I638L	Neutral	0.089
NOTCH3	Q9UM47-1.2	I638M	Neutral	0.307
NOTCH3	Q9UM47-1.2	I638N	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	I638P	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	I638Q	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I638R	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	I638S	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	I638T	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	I638V	Neutral	0.02
NOTCH3	Q9UM47-1.2	I638W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	I638Y	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	N639A	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	N639C	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	N639D	Neutral	0.06
NOTCH3	Q9UM47-1.2	N639E	Neutral	0.22
NOTCH3	Q9UM47-1.2	N639F	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	N639G	Neutral	0.199
NOTCH3	Q9UM47-1.2	N639H	Neutral	0.057
NOTCH3	Q9UM47-1.2	N639I	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	N639K	Neutral	0.204
NOTCH3	Q9UM47-1.2	N639L	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	N639M	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	N639P	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	N639Q	Neutral	0.217
NOTCH3	Q9UM47-1.2	N639R	Neutral	0.196
NOTCH3	Q9UM47-1.2	N639S	Neutral	0.057
NOTCH3	Q9UM47-1.2	N639T	Neutral	0.228
NOTCH3	Q9UM47-1.2	N639V	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	N639W	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	N639Y	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	R640A	Neutral	0.268
NOTCH3	Q9UM47-1.2	R640C	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	R640D	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	R640E	Neutral	0.086
NOTCH3	Q9UM47-1.2	R640F	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	R640G	Pathogenic	0.608
NOTCH3	Q9UM47-1.2	R640H	Neutral	0.089
NOTCH3	Q9UM47-1.2	R640I	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	R640K	Neutral	0.005
NOTCH3	Q9UM47-1.2	R640L	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	R640M	Neutral	0.315
NOTCH3	Q9UM47-1.2	R640N	Neutral	0.082
NOTCH3	Q9UM47-1.2	R640P	Pathogenic	0.647
NOTCH3	Q9UM47-1.2	R640Q	Neutral	0.021
NOTCH3	Q9UM47-1.2	R640S	Neutral	0.272
NOTCH3	Q9UM47-1.2	R640T	Neutral	0.288
NOTCH3	Q9UM47-1.2	R640V	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	R640W	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	R640Y	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	Y641A	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	Y641C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	Y641D	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	Y641E	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	Y641F	Neutral	0.04
NOTCH3	Q9UM47-1.2	Y641G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	Y641H	Neutral	0.151
NOTCH3	Q9UM47-1.2	Y641I	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	Y641K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	Y641L	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	Y641M	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	Y641N	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	Y641P	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	Y641Q	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	Y641R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	Y641S	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	Y641T	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	Y641V	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	Y641W	Neutral	0.152
NOTCH3	Q9UM47-1.2	D642A	Neutral	0.165
NOTCH3	Q9UM47-1.2	D642C	Neutral	0.494
NOTCH3	Q9UM47-1.2	D642E	Neutral	0.0
NOTCH3	Q9UM47-1.2	D642F	Neutral	0.458
NOTCH3	Q9UM47-1.2	D642G	Neutral	0.039
NOTCH3	Q9UM47-1.2	D642H	Neutral	0.041
NOTCH3	Q9UM47-1.2	D642I	Neutral	0.469
NOTCH3	Q9UM47-1.2	D642K	Neutral	0.038
NOTCH3	Q9UM47-1.2	D642L	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	D642M	Neutral	0.468
NOTCH3	Q9UM47-1.2	D642N	Neutral	0.002
NOTCH3	Q9UM47-1.2	D642P	Neutral	0.046
NOTCH3	Q9UM47-1.2	D642Q	Neutral	0.009
NOTCH3	Q9UM47-1.2	D642R	Neutral	0.148
NOTCH3	Q9UM47-1.2	D642S	Neutral	0.01
NOTCH3	Q9UM47-1.2	D642T	Neutral	0.045
NOTCH3	Q9UM47-1.2	D642V	Neutral	0.486
NOTCH3	Q9UM47-1.2	D642W	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	D642Y	Neutral	0.451
NOTCH3	Q9UM47-1.2	C643A	Pathogenic	0.509
NOTCH3	Q9UM47-1.2	C643D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C643E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C643F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	C643G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C643H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C643I	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C643K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C643L	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C643M	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C643N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C643P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C643Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C643R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C643S	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C643T	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	C643V	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C643W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C643Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	V644A	Neutral	0.068
NOTCH3	Q9UM47-1.2	V644C	Neutral	0.261
NOTCH3	Q9UM47-1.2	V644D	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	V644E	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	V644F	Neutral	0.254
NOTCH3	Q9UM47-1.2	V644G	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	V644H	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	V644I	Neutral	0.001
NOTCH3	Q9UM47-1.2	V644K	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	V644L	Neutral	0.017
NOTCH3	Q9UM47-1.2	V644M	Neutral	0.017
NOTCH3	Q9UM47-1.2	V644N	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	V644P	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	V644Q	Pathogenic	0.628
NOTCH3	Q9UM47-1.2	V644R	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	V644S	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	V644T	Neutral	0.074
NOTCH3	Q9UM47-1.2	V644W	Pathogenic	0.864
NOTCH3	Q9UM47-1.2	V644Y	Neutral	0.249
NOTCH3	Q9UM47-1.2	C645A	Pathogenic	0.509
NOTCH3	Q9UM47-1.2	C645D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C645E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C645F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	C645G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C645H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C645I	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C645K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C645L	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C645M	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C645N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C645P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C645Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C645R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C645S	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C645T	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	C645V	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C645W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C645Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	Q646A	Neutral	0.02
NOTCH3	Q9UM47-1.2	Q646C	Neutral	0.312
NOTCH3	Q9UM47-1.2	Q646D	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q646E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q646F	Neutral	0.319
NOTCH3	Q9UM47-1.2	Q646G	Neutral	0.079
NOTCH3	Q9UM47-1.2	Q646H	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q646I	Neutral	0.328
NOTCH3	Q9UM47-1.2	Q646K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q646L	Neutral	0.097
NOTCH3	Q9UM47-1.2	Q646M	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q646N	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q646P	Neutral	0.022
NOTCH3	Q9UM47-1.2	Q646R	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q646S	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q646T	Neutral	0.022
NOTCH3	Q9UM47-1.2	Q646V	Neutral	0.097
NOTCH3	Q9UM47-1.2	Q646W	Neutral	0.085
NOTCH3	Q9UM47-1.2	Q646Y	Neutral	0.021
NOTCH3	Q9UM47-1.2	P647A	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	P647C	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	P647D	Pathogenic	0.654
NOTCH3	Q9UM47-1.2	P647E	Pathogenic	0.637
NOTCH3	Q9UM47-1.2	P647F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	P647G	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	P647H	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	P647I	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	P647K	Pathogenic	0.615
NOTCH3	Q9UM47-1.2	P647L	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	P647M	Pathogenic	0.882
NOTCH3	Q9UM47-1.2	P647N	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	P647Q	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	P647R	Pathogenic	0.873
NOTCH3	Q9UM47-1.2	P647S	Pathogenic	0.638
NOTCH3	Q9UM47-1.2	P647T	Pathogenic	0.65
NOTCH3	Q9UM47-1.2	P647V	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	P647W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	P647Y	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	G648A	Neutral	0.237
NOTCH3	Q9UM47-1.2	G648C	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	G648D	Pathogenic	0.564
NOTCH3	Q9UM47-1.2	G648E	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G648F	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G648H	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	G648I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G648K	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	G648L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G648M	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G648N	Neutral	0.218
NOTCH3	Q9UM47-1.2	G648P	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	G648Q	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	G648R	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	G648S	Neutral	0.232
NOTCH3	Q9UM47-1.2	G648T	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	G648V	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	G648W	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	G648Y	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	F649A	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	F649C	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	F649D	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	F649E	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	F649G	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	F649H	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	F649I	Neutral	0.361
NOTCH3	Q9UM47-1.2	F649K	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	F649L	Neutral	0.362
NOTCH3	Q9UM47-1.2	F649M	Neutral	0.363
NOTCH3	Q9UM47-1.2	F649N	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	F649P	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	F649Q	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	F649R	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	F649S	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	F649T	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	F649V	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	F649W	Neutral	0.105
NOTCH3	Q9UM47-1.2	F649Y	Neutral	0.006
NOTCH3	Q9UM47-1.2	T650A	Neutral	0.384
NOTCH3	Q9UM47-1.2	T650C	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	T650D	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	T650E	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	T650F	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	T650G	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	T650H	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	T650I	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	T650K	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	T650L	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	T650M	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	T650N	Neutral	0.407
NOTCH3	Q9UM47-1.2	T650P	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	T650Q	Pathogenic	0.744
NOTCH3	Q9UM47-1.2	T650R	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	T650S	Neutral	0.123
NOTCH3	Q9UM47-1.2	T650V	Neutral	0.398
NOTCH3	Q9UM47-1.2	T650W	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	T650Y	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	G651A	Neutral	0.244
NOTCH3	Q9UM47-1.2	G651C	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	G651D	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	G651E	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	G651F	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G651H	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G651I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G651K	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	G651L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G651M	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G651N	Neutral	0.224
NOTCH3	Q9UM47-1.2	G651P	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	G651Q	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G651R	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	G651S	Neutral	0.239
NOTCH3	Q9UM47-1.2	G651T	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	G651V	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G651W	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G651Y	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	P652A	Neutral	0.028
NOTCH3	Q9UM47-1.2	P652C	Neutral	0.389
NOTCH3	Q9UM47-1.2	P652D	Neutral	0.03
NOTCH3	Q9UM47-1.2	P652E	Neutral	0.028
NOTCH3	Q9UM47-1.2	P652F	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	P652G	Neutral	0.108
NOTCH3	Q9UM47-1.2	P652H	Neutral	0.113
NOTCH3	Q9UM47-1.2	P652I	Neutral	0.363
NOTCH3	Q9UM47-1.2	P652K	Neutral	0.026
NOTCH3	Q9UM47-1.2	P652L	Neutral	0.363
NOTCH3	Q9UM47-1.2	P652M	Neutral	0.111
NOTCH3	Q9UM47-1.2	P652N	Neutral	0.123
NOTCH3	Q9UM47-1.2	P652Q	Neutral	0.028
NOTCH3	Q9UM47-1.2	P652R	Neutral	0.103
NOTCH3	Q9UM47-1.2	P652S	Neutral	0.028
NOTCH3	Q9UM47-1.2	P652T	Neutral	0.03
NOTCH3	Q9UM47-1.2	P652V	Neutral	0.118
NOTCH3	Q9UM47-1.2	P652W	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	P652Y	Neutral	0.347
NOTCH3	Q9UM47-1.2	L653A	Neutral	0.017
NOTCH3	Q9UM47-1.2	L653C	Neutral	0.018
NOTCH3	Q9UM47-1.2	L653D	Pathogenic	0.647
NOTCH3	Q9UM47-1.2	L653E	Neutral	0.301
NOTCH3	Q9UM47-1.2	L653F	Neutral	0.005
NOTCH3	Q9UM47-1.2	L653G	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	L653H	Neutral	0.307
NOTCH3	Q9UM47-1.2	L653I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L653K	Neutral	0.088
NOTCH3	Q9UM47-1.2	L653M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L653N	Neutral	0.291
NOTCH3	Q9UM47-1.2	L653P	Neutral	0.284
NOTCH3	Q9UM47-1.2	L653Q	Neutral	0.088
NOTCH3	Q9UM47-1.2	L653R	Neutral	0.084
NOTCH3	Q9UM47-1.2	L653S	Neutral	0.076
NOTCH3	Q9UM47-1.2	L653T	Neutral	0.019
NOTCH3	Q9UM47-1.2	L653V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L653W	Neutral	0.078
NOTCH3	Q9UM47-1.2	L653Y	Neutral	0.02
NOTCH3	Q9UM47-1.2	C654A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C654D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C654E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C654F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C654G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C654H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C654I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C654K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C654L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C654M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C654N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C654P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C654Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C654R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C654S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C654T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C654V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C654W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C654Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	N655A	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	N655C	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	N655D	Neutral	0.046
NOTCH3	Q9UM47-1.2	N655E	Neutral	0.174
NOTCH3	Q9UM47-1.2	N655F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	N655G	Neutral	0.156
NOTCH3	Q9UM47-1.2	N655H	Neutral	0.043
NOTCH3	Q9UM47-1.2	N655I	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	N655K	Neutral	0.161
NOTCH3	Q9UM47-1.2	N655L	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	N655M	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	N655P	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	N655Q	Neutral	0.172
NOTCH3	Q9UM47-1.2	N655R	Neutral	0.154
NOTCH3	Q9UM47-1.2	N655S	Neutral	0.043
NOTCH3	Q9UM47-1.2	N655T	Neutral	0.181
NOTCH3	Q9UM47-1.2	N655V	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	N655W	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	N655Y	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	V656A	Neutral	0.057
NOTCH3	Q9UM47-1.2	V656C	Neutral	0.226
NOTCH3	Q9UM47-1.2	V656D	Pathogenic	0.862
NOTCH3	Q9UM47-1.2	V656E	Pathogenic	0.589
NOTCH3	Q9UM47-1.2	V656F	Neutral	0.22
NOTCH3	Q9UM47-1.2	V656G	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	V656H	Pathogenic	0.862
NOTCH3	Q9UM47-1.2	V656I	Neutral	0.001
NOTCH3	Q9UM47-1.2	V656K	Pathogenic	0.565
NOTCH3	Q9UM47-1.2	V656L	Neutral	0.014
NOTCH3	Q9UM47-1.2	V656M	Neutral	0.014
NOTCH3	Q9UM47-1.2	V656N	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	V656P	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	V656Q	Pathogenic	0.583
NOTCH3	Q9UM47-1.2	V656R	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	V656S	Pathogenic	0.561
NOTCH3	Q9UM47-1.2	V656T	Neutral	0.062
NOTCH3	Q9UM47-1.2	V656W	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	V656Y	Neutral	0.215
NOTCH3	Q9UM47-1.2	E657A	Neutral	0.092
NOTCH3	Q9UM47-1.2	E657C	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	E657D	Neutral	0.001
NOTCH3	Q9UM47-1.2	E657F	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	E657G	Neutral	0.3
NOTCH3	Q9UM47-1.2	E657H	Neutral	0.025
NOTCH3	Q9UM47-1.2	E657I	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	E657K	Neutral	0.005
NOTCH3	Q9UM47-1.2	E657L	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	E657M	Neutral	0.341
NOTCH3	Q9UM47-1.2	E657N	Neutral	0.024
NOTCH3	Q9UM47-1.2	E657P	Neutral	0.1
NOTCH3	Q9UM47-1.2	E657Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	E657R	Neutral	0.022
NOTCH3	Q9UM47-1.2	E657S	Neutral	0.022
NOTCH3	Q9UM47-1.2	E657T	Neutral	0.101
NOTCH3	Q9UM47-1.2	E657V	Neutral	0.351
NOTCH3	Q9UM47-1.2	E657W	Pathogenic	0.672
NOTCH3	Q9UM47-1.2	E657Y	Neutral	0.326
NOTCH3	Q9UM47-1.2	I658A	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	I658C	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	I658D	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I658E	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I658F	Pathogenic	0.702
NOTCH3	Q9UM47-1.2	I658G	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	I658H	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I658K	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I658L	Neutral	0.106
NOTCH3	Q9UM47-1.2	I658M	Neutral	0.352
NOTCH3	Q9UM47-1.2	I658N	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I658P	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I658Q	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I658R	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I658S	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	I658T	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	I658V	Neutral	0.024
NOTCH3	Q9UM47-1.2	I658W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I658Y	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	N659A	Neutral	0.448
NOTCH3	Q9UM47-1.2	N659C	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	N659D	Neutral	0.009
NOTCH3	Q9UM47-1.2	N659E	Neutral	0.04
NOTCH3	Q9UM47-1.2	N659F	Pathogenic	0.782
NOTCH3	Q9UM47-1.2	N659G	Neutral	0.035
NOTCH3	Q9UM47-1.2	N659H	Neutral	0.009
NOTCH3	Q9UM47-1.2	N659I	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	N659K	Neutral	0.036
NOTCH3	Q9UM47-1.2	N659L	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	N659M	Neutral	0.451
NOTCH3	Q9UM47-1.2	N659P	Neutral	0.471
NOTCH3	Q9UM47-1.2	N659Q	Neutral	0.039
NOTCH3	Q9UM47-1.2	N659R	Neutral	0.034
NOTCH3	Q9UM47-1.2	N659S	Neutral	0.009
NOTCH3	Q9UM47-1.2	N659T	Neutral	0.041
NOTCH3	Q9UM47-1.2	N659V	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	N659W	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	N659Y	Neutral	0.434
NOTCH3	Q9UM47-1.2	E660A	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	E660C	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	E660D	Neutral	0.034
NOTCH3	Q9UM47-1.2	E660F	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	E660G	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	E660H	Neutral	0.429
NOTCH3	Q9UM47-1.2	E660I	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	E660K	Neutral	0.134
NOTCH3	Q9UM47-1.2	E660L	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	E660M	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	E660N	Neutral	0.424
NOTCH3	Q9UM47-1.2	E660P	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	E660Q	Neutral	0.035
NOTCH3	Q9UM47-1.2	E660R	Neutral	0.4
NOTCH3	Q9UM47-1.2	E660S	Neutral	0.404
NOTCH3	Q9UM47-1.2	E660T	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	E660V	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	E660W	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	E660Y	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	C661A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C661D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C661E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C661F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C661G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C661H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C661I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C661K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C661L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C661M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C661N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C661P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C661Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C661R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C661S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C661T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C661V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C661W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C661Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	A662C	Neutral	0.142
NOTCH3	Q9UM47-1.2	A662D	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	A662E	Neutral	0.408
NOTCH3	Q9UM47-1.2	A662F	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	A662G	Neutral	0.141
NOTCH3	Q9UM47-1.2	A662H	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	A662I	Neutral	0.395
NOTCH3	Q9UM47-1.2	A662K	Neutral	0.385
NOTCH3	Q9UM47-1.2	A662L	Neutral	0.395
NOTCH3	Q9UM47-1.2	A662M	Neutral	0.394
NOTCH3	Q9UM47-1.2	A662N	Pathogenic	0.767
NOTCH3	Q9UM47-1.2	A662P	Neutral	0.425
NOTCH3	Q9UM47-1.2	A662Q	Neutral	0.402
NOTCH3	Q9UM47-1.2	A662R	Neutral	0.373
NOTCH3	Q9UM47-1.2	A662S	Neutral	0.037
NOTCH3	Q9UM47-1.2	A662T	Neutral	0.138
NOTCH3	Q9UM47-1.2	A662V	Neutral	0.133
NOTCH3	Q9UM47-1.2	A662W	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	A662Y	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	S663A	Neutral	0.025
NOTCH3	Q9UM47-1.2	S663C	Neutral	0.345
NOTCH3	Q9UM47-1.2	S663D	Neutral	0.102
NOTCH3	Q9UM47-1.2	S663E	Neutral	0.095
NOTCH3	Q9UM47-1.2	S663F	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	S663G	Neutral	0.099
NOTCH3	Q9UM47-1.2	S663H	Neutral	0.316
NOTCH3	Q9UM47-1.2	S663I	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	S663K	Neutral	0.087
NOTCH3	Q9UM47-1.2	S663L	Pathogenic	0.675
NOTCH3	Q9UM47-1.2	S663M	Neutral	0.313
NOTCH3	Q9UM47-1.2	S663N	Neutral	0.024
NOTCH3	Q9UM47-1.2	S663P	Neutral	0.341
NOTCH3	Q9UM47-1.2	S663Q	Neutral	0.093
NOTCH3	Q9UM47-1.2	S663R	Neutral	0.293
NOTCH3	Q9UM47-1.2	S663T	Neutral	0.024
NOTCH3	Q9UM47-1.2	S663V	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	S663W	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	S663Y	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	S664A	Neutral	0.006
NOTCH3	Q9UM47-1.2	S664C	Neutral	0.113
NOTCH3	Q9UM47-1.2	S664D	Neutral	0.027
NOTCH3	Q9UM47-1.2	S664E	Neutral	0.025
NOTCH3	Q9UM47-1.2	S664F	Neutral	0.326
NOTCH3	Q9UM47-1.2	S664G	Neutral	0.026
NOTCH3	Q9UM47-1.2	S664H	Neutral	0.101
NOTCH3	Q9UM47-1.2	S664I	Neutral	0.335
NOTCH3	Q9UM47-1.2	S664K	Neutral	0.023
NOTCH3	Q9UM47-1.2	S664L	Neutral	0.335
NOTCH3	Q9UM47-1.2	S664M	Neutral	0.099
NOTCH3	Q9UM47-1.2	S664N	Neutral	0.006
NOTCH3	Q9UM47-1.2	S664P	Neutral	0.111
NOTCH3	Q9UM47-1.2	S664Q	Neutral	0.024
NOTCH3	Q9UM47-1.2	S664R	Neutral	0.091
NOTCH3	Q9UM47-1.2	S664T	Neutral	0.006
NOTCH3	Q9UM47-1.2	S664V	Neutral	0.351
NOTCH3	Q9UM47-1.2	S664W	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	S664Y	Neutral	0.319
NOTCH3	Q9UM47-1.2	P665A	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	P665C	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	P665D	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	P665E	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	P665F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P665G	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	P665H	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	P665I	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	P665K	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	P665L	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	P665M	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	P665N	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	P665Q	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	P665R	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	P665S	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	P665T	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	P665V	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	P665W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P665Y	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	C666A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C666D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C666E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C666F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C666G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C666H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C666I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C666K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C666L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C666M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C666N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C666P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C666Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C666R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C666S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C666T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C666V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C666W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C666Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	G667A	Neutral	0.001
NOTCH3	Q9UM47-1.2	G667C	Neutral	0.11
NOTCH3	Q9UM47-1.2	G667D	Neutral	0.006
NOTCH3	Q9UM47-1.2	G667E	Neutral	0.024
NOTCH3	Q9UM47-1.2	G667F	Neutral	0.094
NOTCH3	Q9UM47-1.2	G667H	Neutral	0.023
NOTCH3	Q9UM47-1.2	G667I	Neutral	0.329
NOTCH3	Q9UM47-1.2	G667K	Neutral	0.022
NOTCH3	Q9UM47-1.2	G667L	Neutral	0.329
NOTCH3	Q9UM47-1.2	G667M	Neutral	0.097
NOTCH3	Q9UM47-1.2	G667N	Neutral	0.001
NOTCH3	Q9UM47-1.2	G667P	Neutral	0.026
NOTCH3	Q9UM47-1.2	G667Q	Neutral	0.024
NOTCH3	Q9UM47-1.2	G667R	Neutral	0.021
NOTCH3	Q9UM47-1.2	G667S	Neutral	0.001
NOTCH3	Q9UM47-1.2	G667T	Neutral	0.026
NOTCH3	Q9UM47-1.2	G667V	Neutral	0.103
NOTCH3	Q9UM47-1.2	G667W	Neutral	0.02
NOTCH3	Q9UM47-1.2	G667Y	Neutral	0.091
NOTCH3	Q9UM47-1.2	E668A	Neutral	0.025
NOTCH3	Q9UM47-1.2	E668C	Pathogenic	0.722
NOTCH3	Q9UM47-1.2	E668D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E668F	Neutral	0.363
NOTCH3	Q9UM47-1.2	E668G	Neutral	0.097
NOTCH3	Q9UM47-1.2	E668H	Neutral	0.006
NOTCH3	Q9UM47-1.2	E668I	Neutral	0.372
NOTCH3	Q9UM47-1.2	E668K	Neutral	0.001
NOTCH3	Q9UM47-1.2	E668L	Neutral	0.372
NOTCH3	Q9UM47-1.2	E668M	Neutral	0.115
NOTCH3	Q9UM47-1.2	E668N	Neutral	0.006
NOTCH3	Q9UM47-1.2	E668P	Neutral	0.027
NOTCH3	Q9UM47-1.2	E668Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E668R	Neutral	0.006
NOTCH3	Q9UM47-1.2	E668S	Neutral	0.006
NOTCH3	Q9UM47-1.2	E668T	Neutral	0.027
NOTCH3	Q9UM47-1.2	E668V	Neutral	0.119
NOTCH3	Q9UM47-1.2	E668W	Neutral	0.339
NOTCH3	Q9UM47-1.2	E668Y	Neutral	0.108
NOTCH3	Q9UM47-1.2	G669A	Neutral	0.215
NOTCH3	Q9UM47-1.2	G669C	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G669D	Pathogenic	0.533
NOTCH3	Q9UM47-1.2	G669E	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G669F	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	G669H	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	G669I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G669K	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	G669L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G669M	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G669N	Neutral	0.197
NOTCH3	Q9UM47-1.2	G669P	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	G669Q	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	G669R	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	G669S	Neutral	0.21
NOTCH3	Q9UM47-1.2	G669T	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G669V	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G669W	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	G669Y	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	G670A	Neutral	0.118
NOTCH3	Q9UM47-1.2	G670C	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	G670D	Neutral	0.358
NOTCH3	Q9UM47-1.2	G670E	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	G670F	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	G670H	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	G670I	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	G670K	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	G670L	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	G670M	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	G670N	Neutral	0.107
NOTCH3	Q9UM47-1.2	G670P	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	G670Q	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	G670R	Pathogenic	0.671
NOTCH3	Q9UM47-1.2	G670S	Neutral	0.115
NOTCH3	Q9UM47-1.2	G670T	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	G670V	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	G670W	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	G670Y	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	S671A	Neutral	0.002
NOTCH3	Q9UM47-1.2	S671C	Neutral	0.03
NOTCH3	Q9UM47-1.2	S671D	Neutral	0.007
NOTCH3	Q9UM47-1.2	S671E	Neutral	0.006
NOTCH3	Q9UM47-1.2	S671F	Neutral	0.105
NOTCH3	Q9UM47-1.2	S671G	Neutral	0.006
NOTCH3	Q9UM47-1.2	S671H	Neutral	0.026
NOTCH3	Q9UM47-1.2	S671I	Neutral	0.109
NOTCH3	Q9UM47-1.2	S671K	Neutral	0.006
NOTCH3	Q9UM47-1.2	S671L	Neutral	0.109
NOTCH3	Q9UM47-1.2	S671M	Neutral	0.026
NOTCH3	Q9UM47-1.2	S671N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S671P	Neutral	0.03
NOTCH3	Q9UM47-1.2	S671Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	S671R	Neutral	0.024
NOTCH3	Q9UM47-1.2	S671T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S671V	Neutral	0.116
NOTCH3	Q9UM47-1.2	S671W	Neutral	0.325
NOTCH3	Q9UM47-1.2	S671Y	Neutral	0.102
NOTCH3	Q9UM47-1.2	C672A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C672D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C672E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C672F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C672G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C672H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C672I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C672K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C672L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C672M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C672N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C672P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C672Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C672R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C672S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C672T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C672V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C672W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C672Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	V673A	Neutral	0.021
NOTCH3	Q9UM47-1.2	V673C	Neutral	0.094
NOTCH3	Q9UM47-1.2	V673D	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	V673E	Neutral	0.338
NOTCH3	Q9UM47-1.2	V673F	Neutral	0.091
NOTCH3	Q9UM47-1.2	V673G	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	V673H	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	V673I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V673K	Neutral	0.316
NOTCH3	Q9UM47-1.2	V673L	Neutral	0.005
NOTCH3	Q9UM47-1.2	V673M	Neutral	0.005
NOTCH3	Q9UM47-1.2	V673N	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	V673P	Neutral	0.326
NOTCH3	Q9UM47-1.2	V673Q	Neutral	0.332
NOTCH3	Q9UM47-1.2	V673R	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	V673S	Neutral	0.313
NOTCH3	Q9UM47-1.2	V673T	Neutral	0.023
NOTCH3	Q9UM47-1.2	V673W	Pathogenic	0.652
NOTCH3	Q9UM47-1.2	V673Y	Neutral	0.089
NOTCH3	Q9UM47-1.2	D674A	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	D674C	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	D674E	Neutral	0.011
NOTCH3	Q9UM47-1.2	D674F	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	D674G	Neutral	0.483
NOTCH3	Q9UM47-1.2	D674H	Neutral	0.498
NOTCH3	Q9UM47-1.2	D674I	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	D674K	Neutral	0.481
NOTCH3	Q9UM47-1.2	D674L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	D674M	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	D674N	Neutral	0.049
NOTCH3	Q9UM47-1.2	D674P	Pathogenic	0.525
NOTCH3	Q9UM47-1.2	D674Q	Neutral	0.181
NOTCH3	Q9UM47-1.2	D674R	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	D674S	Neutral	0.184
NOTCH3	Q9UM47-1.2	D674T	Pathogenic	0.523
NOTCH3	Q9UM47-1.2	D674V	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	D674W	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	D674Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	G675A	Neutral	0.016
NOTCH3	Q9UM47-1.2	G675C	Pathogenic	0.583
NOTCH3	Q9UM47-1.2	G675D	Neutral	0.062
NOTCH3	Q9UM47-1.2	G675E	Neutral	0.219
NOTCH3	Q9UM47-1.2	G675F	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	G675H	Neutral	0.212
NOTCH3	Q9UM47-1.2	G675I	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	G675K	Neutral	0.203
NOTCH3	Q9UM47-1.2	G675L	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	G675M	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	G675N	Neutral	0.014
NOTCH3	Q9UM47-1.2	G675P	Neutral	0.232
NOTCH3	Q9UM47-1.2	G675Q	Neutral	0.215
NOTCH3	Q9UM47-1.2	G675R	Neutral	0.195
NOTCH3	Q9UM47-1.2	G675S	Neutral	0.015
NOTCH3	Q9UM47-1.2	G675T	Neutral	0.229
NOTCH3	Q9UM47-1.2	G675V	Pathogenic	0.566
NOTCH3	Q9UM47-1.2	G675W	Neutral	0.187
NOTCH3	Q9UM47-1.2	G675Y	Pathogenic	0.531
NOTCH3	Q9UM47-1.2	E676A	Neutral	0.072
NOTCH3	Q9UM47-1.2	E676C	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	E676D	Neutral	0.001
NOTCH3	Q9UM47-1.2	E676F	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	E676G	Neutral	0.247
NOTCH3	Q9UM47-1.2	E676H	Neutral	0.019
NOTCH3	Q9UM47-1.2	E676I	Pathogenic	0.644
NOTCH3	Q9UM47-1.2	E676K	Neutral	0.004
NOTCH3	Q9UM47-1.2	E676L	Pathogenic	0.644
NOTCH3	Q9UM47-1.2	E676M	Neutral	0.283
NOTCH3	Q9UM47-1.2	E676N	Neutral	0.019
NOTCH3	Q9UM47-1.2	E676P	Neutral	0.078
NOTCH3	Q9UM47-1.2	E676Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	E676R	Neutral	0.017
NOTCH3	Q9UM47-1.2	E676S	Neutral	0.017
NOTCH3	Q9UM47-1.2	E676T	Neutral	0.079
NOTCH3	Q9UM47-1.2	E676V	Neutral	0.292
NOTCH3	Q9UM47-1.2	E676W	Pathogenic	0.609
NOTCH3	Q9UM47-1.2	E676Y	Neutral	0.27
NOTCH3	Q9UM47-1.2	N677A	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	N677C	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	N677D	Neutral	0.117
NOTCH3	Q9UM47-1.2	N677E	Neutral	0.369
NOTCH3	Q9UM47-1.2	N677F	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	N677G	Neutral	0.339
NOTCH3	Q9UM47-1.2	N677H	Neutral	0.111
NOTCH3	Q9UM47-1.2	N677I	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	N677K	Neutral	0.347
NOTCH3	Q9UM47-1.2	N677L	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	N677M	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	N677P	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	N677Q	Neutral	0.365
NOTCH3	Q9UM47-1.2	N677R	Neutral	0.335
NOTCH3	Q9UM47-1.2	N677S	Neutral	0.11
NOTCH3	Q9UM47-1.2	N677T	Neutral	0.38
NOTCH3	Q9UM47-1.2	N677V	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	N677W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	N677Y	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	G678A	Neutral	0.101
NOTCH3	Q9UM47-1.2	G678C	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	G678D	Neutral	0.319
NOTCH3	Q9UM47-1.2	G678E	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	G678F	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	G678H	Pathogenic	0.656
NOTCH3	Q9UM47-1.2	G678I	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	G678K	Pathogenic	0.643
NOTCH3	Q9UM47-1.2	G678L	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	G678M	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	G678N	Neutral	0.091
NOTCH3	Q9UM47-1.2	G678P	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	G678Q	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	G678R	Pathogenic	0.631
NOTCH3	Q9UM47-1.2	G678S	Neutral	0.099
NOTCH3	Q9UM47-1.2	G678T	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	G678V	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	G678W	Pathogenic	0.62
NOTCH3	Q9UM47-1.2	G678Y	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	F679A	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	F679C	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	F679D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F679E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F679G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F679H	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	F679I	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	F679K	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F679L	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	F679M	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	F679N	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F679P	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	F679Q	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F679R	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F679S	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	F679T	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	F679V	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	F679W	Neutral	0.4
NOTCH3	Q9UM47-1.2	F679Y	Neutral	0.034
NOTCH3	Q9UM47-1.2	R680A	Neutral	0.192
NOTCH3	Q9UM47-1.2	R680C	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	R680D	Pathogenic	0.541
NOTCH3	Q9UM47-1.2	R680E	Neutral	0.058
NOTCH3	Q9UM47-1.2	R680F	Pathogenic	0.867
NOTCH3	Q9UM47-1.2	R680G	Pathogenic	0.502
NOTCH3	Q9UM47-1.2	R680H	Neutral	0.06
NOTCH3	Q9UM47-1.2	R680I	Pathogenic	0.862
NOTCH3	Q9UM47-1.2	R680K	Neutral	0.003
NOTCH3	Q9UM47-1.2	R680L	Pathogenic	0.578
NOTCH3	Q9UM47-1.2	R680M	Neutral	0.23
NOTCH3	Q9UM47-1.2	R680N	Neutral	0.055
NOTCH3	Q9UM47-1.2	R680P	Pathogenic	0.543
NOTCH3	Q9UM47-1.2	R680Q	Neutral	0.014
NOTCH3	Q9UM47-1.2	R680S	Neutral	0.196
NOTCH3	Q9UM47-1.2	R680T	Neutral	0.208
NOTCH3	Q9UM47-1.2	R680V	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	R680W	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	R680Y	Pathogenic	0.592
NOTCH3	Q9UM47-1.2	C681A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C681D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C681E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C681F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C681G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C681H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C681I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C681K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C681L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C681M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C681N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C681P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C681Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C681R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C681S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C681T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C681V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C681W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C681Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	L682A	Neutral	0.061
NOTCH3	Q9UM47-1.2	L682C	Neutral	0.065
NOTCH3	Q9UM47-1.2	L682D	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	L682E	Pathogenic	0.613
NOTCH3	Q9UM47-1.2	L682F	Neutral	0.016
NOTCH3	Q9UM47-1.2	L682G	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	L682H	Pathogenic	0.619
NOTCH3	Q9UM47-1.2	L682I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L682K	Neutral	0.261
NOTCH3	Q9UM47-1.2	L682M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L682N	Pathogenic	0.601
NOTCH3	Q9UM47-1.2	L682P	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	L682Q	Neutral	0.261
NOTCH3	Q9UM47-1.2	L682R	Neutral	0.252
NOTCH3	Q9UM47-1.2	L682S	Neutral	0.231
NOTCH3	Q9UM47-1.2	L682T	Neutral	0.067
NOTCH3	Q9UM47-1.2	L682V	Neutral	0.004
NOTCH3	Q9UM47-1.2	L682W	Neutral	0.238
NOTCH3	Q9UM47-1.2	L682Y	Neutral	0.07
NOTCH3	Q9UM47-1.2	C683A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C683D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C683E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C683F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C683G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C683H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C683I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C683K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C683L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C683M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C683N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C683P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C683Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C683R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C683S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C683T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C683V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C683W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C683Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	P684A	Pathogenic	0.67
NOTCH3	Q9UM47-1.2	P684C	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P684D	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	P684E	Pathogenic	0.675
NOTCH3	Q9UM47-1.2	P684F	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P684G	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	P684H	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	P684I	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	P684K	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	P684L	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	P684M	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	P684N	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	P684Q	Pathogenic	0.67
NOTCH3	Q9UM47-1.2	P684R	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	P684S	Pathogenic	0.675
NOTCH3	Q9UM47-1.2	P684T	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	P684V	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	P684W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P684Y	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	P685A	Neutral	0.032
NOTCH3	Q9UM47-1.2	P685C	Neutral	0.423
NOTCH3	Q9UM47-1.2	P685D	Neutral	0.035
NOTCH3	Q9UM47-1.2	P685E	Neutral	0.033
NOTCH3	Q9UM47-1.2	P685F	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	P685G	Neutral	0.122
NOTCH3	Q9UM47-1.2	P685H	Neutral	0.128
NOTCH3	Q9UM47-1.2	P685I	Neutral	0.396
NOTCH3	Q9UM47-1.2	P685K	Neutral	0.03
NOTCH3	Q9UM47-1.2	P685L	Neutral	0.396
NOTCH3	Q9UM47-1.2	P685M	Neutral	0.126
NOTCH3	Q9UM47-1.2	P685N	Neutral	0.139
NOTCH3	Q9UM47-1.2	P685Q	Neutral	0.032
NOTCH3	Q9UM47-1.2	P685R	Neutral	0.117
NOTCH3	Q9UM47-1.2	P685S	Neutral	0.033
NOTCH3	Q9UM47-1.2	P685T	Neutral	0.034
NOTCH3	Q9UM47-1.2	P685V	Neutral	0.134
NOTCH3	Q9UM47-1.2	P685W	Pathogenic	0.721
NOTCH3	Q9UM47-1.2	P685Y	Neutral	0.379
NOTCH3	Q9UM47-1.2	G686A	Neutral	0.21
NOTCH3	Q9UM47-1.2	G686C	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G686D	Pathogenic	0.525
NOTCH3	Q9UM47-1.2	G686E	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G686F	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	G686H	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	G686I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G686K	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	G686L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G686M	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	G686N	Neutral	0.192
NOTCH3	Q9UM47-1.2	G686P	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G686Q	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	G686R	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	G686S	Neutral	0.206
NOTCH3	Q9UM47-1.2	G686T	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	G686V	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G686W	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	G686Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	S687A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S687C	Neutral	0.017
NOTCH3	Q9UM47-1.2	S687D	Neutral	0.004
NOTCH3	Q9UM47-1.2	S687E	Neutral	0.003
NOTCH3	Q9UM47-1.2	S687F	Neutral	0.062
NOTCH3	Q9UM47-1.2	S687G	Neutral	0.004
NOTCH3	Q9UM47-1.2	S687H	Neutral	0.015
NOTCH3	Q9UM47-1.2	S687I	Neutral	0.064
NOTCH3	Q9UM47-1.2	S687K	Neutral	0.003
NOTCH3	Q9UM47-1.2	S687L	Neutral	0.064
NOTCH3	Q9UM47-1.2	S687M	Neutral	0.015
NOTCH3	Q9UM47-1.2	S687N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S687P	Neutral	0.017
NOTCH3	Q9UM47-1.2	S687Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	S687R	Neutral	0.013
NOTCH3	Q9UM47-1.2	S687T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S687V	Neutral	0.068
NOTCH3	Q9UM47-1.2	S687W	Neutral	0.212
NOTCH3	Q9UM47-1.2	S687Y	Neutral	0.06
NOTCH3	Q9UM47-1.2	L688A	Neutral	0.019
NOTCH3	Q9UM47-1.2	L688C	Neutral	0.02
NOTCH3	Q9UM47-1.2	L688D	Pathogenic	0.664
NOTCH3	Q9UM47-1.2	L688E	Neutral	0.317
NOTCH3	Q9UM47-1.2	L688F	Neutral	0.005
NOTCH3	Q9UM47-1.2	L688G	Pathogenic	0.625
NOTCH3	Q9UM47-1.2	L688H	Neutral	0.324
NOTCH3	Q9UM47-1.2	L688I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L688K	Neutral	0.094
NOTCH3	Q9UM47-1.2	L688M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L688N	Neutral	0.307
NOTCH3	Q9UM47-1.2	L688P	Neutral	0.299
NOTCH3	Q9UM47-1.2	L688Q	Neutral	0.094
NOTCH3	Q9UM47-1.2	L688R	Neutral	0.09
NOTCH3	Q9UM47-1.2	L688S	Neutral	0.081
NOTCH3	Q9UM47-1.2	L688T	Neutral	0.021
NOTCH3	Q9UM47-1.2	L688V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L688W	Neutral	0.084
NOTCH3	Q9UM47-1.2	L688Y	Neutral	0.022
NOTCH3	Q9UM47-1.2	P689A	Neutral	0.027
NOTCH3	Q9UM47-1.2	P689C	Neutral	0.381
NOTCH3	Q9UM47-1.2	P689D	Neutral	0.029
NOTCH3	Q9UM47-1.2	P689E	Neutral	0.027
NOTCH3	Q9UM47-1.2	P689F	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	P689G	Neutral	0.105
NOTCH3	Q9UM47-1.2	P689H	Neutral	0.11
NOTCH3	Q9UM47-1.2	P689I	Neutral	0.355
NOTCH3	Q9UM47-1.2	P689K	Neutral	0.025
NOTCH3	Q9UM47-1.2	P689L	Neutral	0.355
NOTCH3	Q9UM47-1.2	P689M	Neutral	0.108
NOTCH3	Q9UM47-1.2	P689N	Neutral	0.119
NOTCH3	Q9UM47-1.2	P689Q	Neutral	0.027
NOTCH3	Q9UM47-1.2	P689R	Neutral	0.1
NOTCH3	Q9UM47-1.2	P689S	Neutral	0.028
NOTCH3	Q9UM47-1.2	P689T	Neutral	0.029
NOTCH3	Q9UM47-1.2	P689V	Neutral	0.115
NOTCH3	Q9UM47-1.2	P689W	Pathogenic	0.684
NOTCH3	Q9UM47-1.2	P689Y	Neutral	0.339
NOTCH3	Q9UM47-1.2	P690A	Neutral	0.348
NOTCH3	Q9UM47-1.2	P690C	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	P690D	Neutral	0.369
NOTCH3	Q9UM47-1.2	P690E	Neutral	0.353
NOTCH3	Q9UM47-1.2	P690F	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	P690G	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	P690H	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	P690I	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	P690K	Neutral	0.331
NOTCH3	Q9UM47-1.2	P690L	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	P690M	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	P690N	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	P690Q	Neutral	0.348
NOTCH3	Q9UM47-1.2	P690R	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	P690S	Neutral	0.354
NOTCH3	Q9UM47-1.2	P690T	Neutral	0.366
NOTCH3	Q9UM47-1.2	P690V	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	P690W	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	P690Y	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	L691A	Neutral	0.023
NOTCH3	Q9UM47-1.2	L691C	Neutral	0.025
NOTCH3	Q9UM47-1.2	L691D	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	L691E	Neutral	0.366
NOTCH3	Q9UM47-1.2	L691F	Neutral	0.006
NOTCH3	Q9UM47-1.2	L691G	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	L691H	Neutral	0.373
NOTCH3	Q9UM47-1.2	L691I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L691K	Neutral	0.115
NOTCH3	Q9UM47-1.2	L691M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L691N	Neutral	0.355
NOTCH3	Q9UM47-1.2	L691P	Neutral	0.347
NOTCH3	Q9UM47-1.2	L691Q	Neutral	0.114
NOTCH3	Q9UM47-1.2	L691R	Neutral	0.11
NOTCH3	Q9UM47-1.2	L691S	Neutral	0.099
NOTCH3	Q9UM47-1.2	L691T	Neutral	0.025
NOTCH3	Q9UM47-1.2	L691V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L691W	Neutral	0.102
NOTCH3	Q9UM47-1.2	L691Y	Neutral	0.027
NOTCH3	Q9UM47-1.2	C692A	Pathogenic	0.511
NOTCH3	Q9UM47-1.2	C692D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C692E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C692F	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	C692G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C692H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C692I	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C692K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C692L	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C692M	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C692N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C692P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C692Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C692R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C692S	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	C692T	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C692V	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C692W	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	C692Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	L693A	Neutral	0.21
NOTCH3	Q9UM47-1.2	L693C	Neutral	0.221
NOTCH3	Q9UM47-1.2	L693D	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	L693E	Pathogenic	0.867
NOTCH3	Q9UM47-1.2	L693F	Neutral	0.065
NOTCH3	Q9UM47-1.2	L693G	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	L693H	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	L693I	Neutral	0.003
NOTCH3	Q9UM47-1.2	L693K	Pathogenic	0.594
NOTCH3	Q9UM47-1.2	L693M	Neutral	0.003
NOTCH3	Q9UM47-1.2	L693N	Pathogenic	0.861
NOTCH3	Q9UM47-1.2	L693P	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	L693Q	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	L693R	Pathogenic	0.581
NOTCH3	Q9UM47-1.2	L693S	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	L693T	Neutral	0.227
NOTCH3	Q9UM47-1.2	L693V	Neutral	0.015
NOTCH3	Q9UM47-1.2	L693W	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	L693Y	Neutral	0.236
NOTCH3	Q9UM47-1.2	P694A	Neutral	0.046
NOTCH3	Q9UM47-1.2	P694C	Pathogenic	0.517
NOTCH3	Q9UM47-1.2	P694D	Neutral	0.05
NOTCH3	Q9UM47-1.2	P694E	Neutral	0.047
NOTCH3	Q9UM47-1.2	P694F	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	P694G	Neutral	0.169
NOTCH3	Q9UM47-1.2	P694H	Neutral	0.177
NOTCH3	Q9UM47-1.2	P694I	Neutral	0.49
NOTCH3	Q9UM47-1.2	P694K	Neutral	0.043
NOTCH3	Q9UM47-1.2	P694L	Neutral	0.49
NOTCH3	Q9UM47-1.2	P694M	Neutral	0.174
NOTCH3	Q9UM47-1.2	P694N	Neutral	0.191
NOTCH3	Q9UM47-1.2	P694Q	Neutral	0.046
NOTCH3	Q9UM47-1.2	P694R	Neutral	0.162
NOTCH3	Q9UM47-1.2	P694S	Neutral	0.047
NOTCH3	Q9UM47-1.2	P694T	Neutral	0.049
NOTCH3	Q9UM47-1.2	P694V	Neutral	0.184
NOTCH3	Q9UM47-1.2	P694W	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	P694Y	Neutral	0.472
NOTCH3	Q9UM47-1.2	P695A	Neutral	0.009
NOTCH3	Q9UM47-1.2	P695C	Neutral	0.17
NOTCH3	Q9UM47-1.2	P695D	Neutral	0.01
NOTCH3	Q9UM47-1.2	P695E	Neutral	0.009
NOTCH3	Q9UM47-1.2	P695F	Neutral	0.445
NOTCH3	Q9UM47-1.2	P695G	Neutral	0.037
NOTCH3	Q9UM47-1.2	P695H	Neutral	0.039
NOTCH3	Q9UM47-1.2	P695I	Neutral	0.155
NOTCH3	Q9UM47-1.2	P695K	Neutral	0.008
NOTCH3	Q9UM47-1.2	P695L	Neutral	0.155
NOTCH3	Q9UM47-1.2	P695M	Neutral	0.039
NOTCH3	Q9UM47-1.2	P695N	Neutral	0.043
NOTCH3	Q9UM47-1.2	P695Q	Neutral	0.009
NOTCH3	Q9UM47-1.2	P695R	Neutral	0.036
NOTCH3	Q9UM47-1.2	P695S	Neutral	0.009
NOTCH3	Q9UM47-1.2	P695T	Neutral	0.01
NOTCH3	Q9UM47-1.2	P695V	Neutral	0.041
NOTCH3	Q9UM47-1.2	P695W	Neutral	0.419
NOTCH3	Q9UM47-1.2	P695Y	Neutral	0.146
NOTCH3	Q9UM47-1.2	S696A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S696C	Neutral	0.018
NOTCH3	Q9UM47-1.2	S696D	Neutral	0.004
NOTCH3	Q9UM47-1.2	S696E	Neutral	0.004
NOTCH3	Q9UM47-1.2	S696F	Neutral	0.066
NOTCH3	Q9UM47-1.2	S696G	Neutral	0.004
NOTCH3	Q9UM47-1.2	S696H	Neutral	0.016
NOTCH3	Q9UM47-1.2	S696I	Neutral	0.068
NOTCH3	Q9UM47-1.2	S696K	Neutral	0.003
NOTCH3	Q9UM47-1.2	S696L	Neutral	0.068
NOTCH3	Q9UM47-1.2	S696M	Neutral	0.016
NOTCH3	Q9UM47-1.2	S696N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S696P	Neutral	0.018
NOTCH3	Q9UM47-1.2	S696Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	S696R	Neutral	0.014
NOTCH3	Q9UM47-1.2	S696T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S696V	Neutral	0.073
NOTCH3	Q9UM47-1.2	S696W	Neutral	0.224
NOTCH3	Q9UM47-1.2	S696Y	Neutral	0.064
NOTCH3	Q9UM47-1.2	H697A	Neutral	0.366
NOTCH3	Q9UM47-1.2	H697C	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	H697D	Neutral	0.123
NOTCH3	Q9UM47-1.2	H697E	Neutral	0.032
NOTCH3	Q9UM47-1.2	H697F	Neutral	0.128
NOTCH3	Q9UM47-1.2	H697G	Neutral	0.349
NOTCH3	Q9UM47-1.2	H697I	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	H697K	Neutral	0.127
NOTCH3	Q9UM47-1.2	H697L	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	H697M	Neutral	0.409
NOTCH3	Q9UM47-1.2	H697N	Neutral	0.007
NOTCH3	Q9UM47-1.2	H697P	Neutral	0.388
NOTCH3	Q9UM47-1.2	H697Q	Neutral	0.032
NOTCH3	Q9UM47-1.2	H697R	Neutral	0.03
NOTCH3	Q9UM47-1.2	H697S	Neutral	0.115
NOTCH3	Q9UM47-1.2	H697T	Neutral	0.39
NOTCH3	Q9UM47-1.2	H697V	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	H697W	Neutral	0.375
NOTCH3	Q9UM47-1.2	H697Y	Neutral	0.002
NOTCH3	Q9UM47-1.2	P698A	Neutral	0.028
NOTCH3	Q9UM47-1.2	P698C	Neutral	0.389
NOTCH3	Q9UM47-1.2	P698D	Neutral	0.03
NOTCH3	Q9UM47-1.2	P698E	Neutral	0.028
NOTCH3	Q9UM47-1.2	P698F	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	P698G	Neutral	0.108
NOTCH3	Q9UM47-1.2	P698H	Neutral	0.113
NOTCH3	Q9UM47-1.2	P698I	Neutral	0.364
NOTCH3	Q9UM47-1.2	P698K	Neutral	0.026
NOTCH3	Q9UM47-1.2	P698L	Neutral	0.363
NOTCH3	Q9UM47-1.2	P698M	Neutral	0.111
NOTCH3	Q9UM47-1.2	P698N	Neutral	0.123
NOTCH3	Q9UM47-1.2	P698Q	Neutral	0.028
NOTCH3	Q9UM47-1.2	P698R	Neutral	0.103
NOTCH3	Q9UM47-1.2	P698S	Neutral	0.029
NOTCH3	Q9UM47-1.2	P698T	Neutral	0.03
NOTCH3	Q9UM47-1.2	P698V	Neutral	0.118
NOTCH3	Q9UM47-1.2	P698W	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	P698Y	Neutral	0.347
NOTCH3	Q9UM47-1.2	C699A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C699D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C699E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C699F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C699G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C699H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C699I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C699K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C699L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C699M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C699N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C699P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C699Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C699R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C699S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C699T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C699V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C699W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C699Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	A700C	Neutral	0.009
NOTCH3	Q9UM47-1.2	A700D	Neutral	0.152
NOTCH3	Q9UM47-1.2	A700E	Neutral	0.036
NOTCH3	Q9UM47-1.2	A700F	Neutral	0.132
NOTCH3	Q9UM47-1.2	A700G	Neutral	0.009
NOTCH3	Q9UM47-1.2	A700H	Neutral	0.139
NOTCH3	Q9UM47-1.2	A700I	Neutral	0.034
NOTCH3	Q9UM47-1.2	A700K	Neutral	0.032
NOTCH3	Q9UM47-1.2	A700L	Neutral	0.034
NOTCH3	Q9UM47-1.2	A700M	Neutral	0.034
NOTCH3	Q9UM47-1.2	A700N	Neutral	0.15
NOTCH3	Q9UM47-1.2	A700P	Neutral	0.038
NOTCH3	Q9UM47-1.2	A700Q	Neutral	0.035
NOTCH3	Q9UM47-1.2	A700R	Neutral	0.031
NOTCH3	Q9UM47-1.2	A700S	Neutral	0.002
NOTCH3	Q9UM47-1.2	A700T	Neutral	0.008
NOTCH3	Q9UM47-1.2	A700V	Neutral	0.008
NOTCH3	Q9UM47-1.2	A700W	Neutral	0.385
NOTCH3	Q9UM47-1.2	A700Y	Neutral	0.129
NOTCH3	Q9UM47-1.2	H701A	Neutral	0.195
NOTCH3	Q9UM47-1.2	H701C	Pathogenic	0.544
NOTCH3	Q9UM47-1.2	H701D	Neutral	0.055
NOTCH3	Q9UM47-1.2	H701E	Neutral	0.014
NOTCH3	Q9UM47-1.2	H701F	Neutral	0.058
NOTCH3	Q9UM47-1.2	H701G	Neutral	0.184
NOTCH3	Q9UM47-1.2	H701I	Pathogenic	0.571
NOTCH3	Q9UM47-1.2	H701K	Neutral	0.058
NOTCH3	Q9UM47-1.2	H701L	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	H701M	Neutral	0.225
NOTCH3	Q9UM47-1.2	H701N	Neutral	0.003
NOTCH3	Q9UM47-1.2	H701P	Neutral	0.21
NOTCH3	Q9UM47-1.2	H701Q	Neutral	0.014
NOTCH3	Q9UM47-1.2	H701R	Neutral	0.013
NOTCH3	Q9UM47-1.2	H701S	Neutral	0.052
NOTCH3	Q9UM47-1.2	H701T	Neutral	0.211
NOTCH3	Q9UM47-1.2	H701V	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	H701W	Neutral	0.201
NOTCH3	Q9UM47-1.2	H701Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	E702A	Neutral	0.027
NOTCH3	Q9UM47-1.2	E702C	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	E702D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E702F	Neutral	0.383
NOTCH3	Q9UM47-1.2	E702G	Neutral	0.105
NOTCH3	Q9UM47-1.2	E702H	Neutral	0.007
NOTCH3	Q9UM47-1.2	E702I	Neutral	0.393
NOTCH3	Q9UM47-1.2	E702K	Neutral	0.001
NOTCH3	Q9UM47-1.2	E702L	Neutral	0.393
NOTCH3	Q9UM47-1.2	E702M	Neutral	0.124
NOTCH3	Q9UM47-1.2	E702N	Neutral	0.007
NOTCH3	Q9UM47-1.2	E702P	Neutral	0.03
NOTCH3	Q9UM47-1.2	E702Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E702R	Neutral	0.006
NOTCH3	Q9UM47-1.2	E702S	Neutral	0.006
NOTCH3	Q9UM47-1.2	E702T	Neutral	0.03
NOTCH3	Q9UM47-1.2	E702V	Neutral	0.129
NOTCH3	Q9UM47-1.2	E702W	Neutral	0.358
NOTCH3	Q9UM47-1.2	E702Y	Neutral	0.117
NOTCH3	Q9UM47-1.2	P703A	Pathogenic	0.684
NOTCH3	Q9UM47-1.2	P703C	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	P703D	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	P703E	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	P703F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P703G	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	P703H	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	P703I	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	P703K	Pathogenic	0.668
NOTCH3	Q9UM47-1.2	P703L	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	P703M	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	P703N	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	P703Q	Pathogenic	0.684
NOTCH3	Q9UM47-1.2	P703R	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	P703S	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	P703T	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	P703V	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	P703W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P703Y	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	C704A	Pathogenic	0.511
NOTCH3	Q9UM47-1.2	C704D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C704E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C704F	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	C704G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C704H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C704I	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C704K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C704L	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C704M	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C704N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C704P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C704Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C704R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C704S	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	C704T	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C704V	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C704W	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	C704Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	S705A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S705C	Neutral	0.013
NOTCH3	Q9UM47-1.2	S705D	Neutral	0.003
NOTCH3	Q9UM47-1.2	S705E	Neutral	0.003
NOTCH3	Q9UM47-1.2	S705F	Neutral	0.048
NOTCH3	Q9UM47-1.2	S705G	Neutral	0.003
NOTCH3	Q9UM47-1.2	S705H	Neutral	0.012
NOTCH3	Q9UM47-1.2	S705I	Neutral	0.05
NOTCH3	Q9UM47-1.2	S705K	Neutral	0.002
NOTCH3	Q9UM47-1.2	S705L	Neutral	0.05
NOTCH3	Q9UM47-1.2	S705M	Neutral	0.011
NOTCH3	Q9UM47-1.2	S705N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S705P	Neutral	0.013
NOTCH3	Q9UM47-1.2	S705Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	S705R	Neutral	0.01
NOTCH3	Q9UM47-1.2	S705T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S705V	Neutral	0.053
NOTCH3	Q9UM47-1.2	S705W	Neutral	0.171
NOTCH3	Q9UM47-1.2	S705Y	Neutral	0.047
NOTCH3	Q9UM47-1.2	H706A	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	H706C	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	H706D	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	H706E	Pathogenic	0.614
NOTCH3	Q9UM47-1.2	H706F	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	H706G	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	H706I	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	H706K	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	H706L	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	H706M	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	H706N	Neutral	0.25
NOTCH3	Q9UM47-1.2	H706P	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	H706Q	Pathogenic	0.618
NOTCH3	Q9UM47-1.2	H706R	Pathogenic	0.596
NOTCH3	Q9UM47-1.2	H706S	Pathogenic	0.863
NOTCH3	Q9UM47-1.2	H706T	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	H706V	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	H706W	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	H706Y	Neutral	0.068
NOTCH3	Q9UM47-1.2	G707A	Neutral	0.245
NOTCH3	Q9UM47-1.2	G707C	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	G707D	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	G707E	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	G707F	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G707H	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G707I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G707K	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	G707L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G707M	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G707N	Neutral	0.225
NOTCH3	Q9UM47-1.2	G707P	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	G707Q	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G707R	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	G707S	Neutral	0.24
NOTCH3	Q9UM47-1.2	G707T	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	G707V	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G707W	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	G707Y	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	I708A	Neutral	0.004
NOTCH3	Q9UM47-1.2	I708C	Neutral	0.004
NOTCH3	Q9UM47-1.2	I708D	Neutral	0.088
NOTCH3	Q9UM47-1.2	I708E	Neutral	0.093
NOTCH3	Q9UM47-1.2	I708F	Neutral	0.001
NOTCH3	Q9UM47-1.2	I708G	Neutral	0.269
NOTCH3	Q9UM47-1.2	I708H	Neutral	0.096
NOTCH3	Q9UM47-1.2	I708K	Neutral	0.095
NOTCH3	Q9UM47-1.2	I708L	Neutral	0.0
NOTCH3	Q9UM47-1.2	I708M	Neutral	0.0
NOTCH3	Q9UM47-1.2	I708N	Neutral	0.089
NOTCH3	Q9UM47-1.2	I708P	Neutral	0.086
NOTCH3	Q9UM47-1.2	I708Q	Neutral	0.094
NOTCH3	Q9UM47-1.2	I708R	Neutral	0.09
NOTCH3	Q9UM47-1.2	I708S	Neutral	0.019
NOTCH3	Q9UM47-1.2	I708T	Neutral	0.005
NOTCH3	Q9UM47-1.2	I708V	Neutral	0.0
NOTCH3	Q9UM47-1.2	I708W	Neutral	0.084
NOTCH3	Q9UM47-1.2	I708Y	Neutral	0.005
NOTCH3	Q9UM47-1.2	C709A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C709D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C709E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C709F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C709G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C709H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C709I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C709K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C709L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C709M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C709N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C709P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C709Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C709R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C709S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C709T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C709V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C709W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C709Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	Y710A	Neutral	0.018
NOTCH3	Q9UM47-1.2	Y710C	Neutral	0.019
NOTCH3	Q9UM47-1.2	Y710D	Neutral	0.084
NOTCH3	Q9UM47-1.2	Y710E	Neutral	0.021
NOTCH3	Q9UM47-1.2	Y710F	Neutral	0.0
NOTCH3	Q9UM47-1.2	Y710G	Neutral	0.071
NOTCH3	Q9UM47-1.2	Y710H	Neutral	0.0
NOTCH3	Q9UM47-1.2	Y710I	Neutral	0.005
NOTCH3	Q9UM47-1.2	Y710K	Neutral	0.023
NOTCH3	Q9UM47-1.2	Y710L	Neutral	0.005
NOTCH3	Q9UM47-1.2	Y710M	Neutral	0.005
NOTCH3	Q9UM47-1.2	Y710N	Neutral	0.02
NOTCH3	Q9UM47-1.2	Y710P	Neutral	0.082
NOTCH3	Q9UM47-1.2	Y710Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	Y710R	Neutral	0.023
NOTCH3	Q9UM47-1.2	Y710S	Neutral	0.018
NOTCH3	Q9UM47-1.2	Y710T	Neutral	0.02
NOTCH3	Q9UM47-1.2	Y710V	Neutral	0.005
NOTCH3	Q9UM47-1.2	Y710W	Neutral	0.0
NOTCH3	Q9UM47-1.2	D711A	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	D711C	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	D711E	Neutral	0.006
NOTCH3	Q9UM47-1.2	D711F	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	D711G	Neutral	0.338
NOTCH3	Q9UM47-1.2	D711H	Neutral	0.352
NOTCH3	Q9UM47-1.2	D711I	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	D711K	Neutral	0.336
NOTCH3	Q9UM47-1.2	D711L	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	D711M	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	D711N	Neutral	0.028
NOTCH3	Q9UM47-1.2	D711P	Neutral	0.377
NOTCH3	Q9UM47-1.2	D711Q	Neutral	0.108
NOTCH3	Q9UM47-1.2	D711R	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	D711S	Neutral	0.11
NOTCH3	Q9UM47-1.2	D711T	Neutral	0.375
NOTCH3	Q9UM47-1.2	D711V	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	D711W	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	D711Y	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	A712C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A712D	Neutral	0.059
NOTCH3	Q9UM47-1.2	A712E	Neutral	0.013
NOTCH3	Q9UM47-1.2	A712F	Neutral	0.051
NOTCH3	Q9UM47-1.2	A712G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A712H	Neutral	0.053
NOTCH3	Q9UM47-1.2	A712I	Neutral	0.012
NOTCH3	Q9UM47-1.2	A712K	Neutral	0.012
NOTCH3	Q9UM47-1.2	A712L	Neutral	0.012
NOTCH3	Q9UM47-1.2	A712M	Neutral	0.012
NOTCH3	Q9UM47-1.2	A712N	Neutral	0.058
NOTCH3	Q9UM47-1.2	A712P	Neutral	0.014
NOTCH3	Q9UM47-1.2	A712Q	Neutral	0.012
NOTCH3	Q9UM47-1.2	A712R	Neutral	0.011
NOTCH3	Q9UM47-1.2	A712S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A712T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A712V	Neutral	0.003
NOTCH3	Q9UM47-1.2	A712W	Neutral	0.18
NOTCH3	Q9UM47-1.2	A712Y	Neutral	0.049
NOTCH3	Q9UM47-1.2	P713A	Neutral	0.014
NOTCH3	Q9UM47-1.2	P713C	Neutral	0.246
NOTCH3	Q9UM47-1.2	P713D	Neutral	0.016
NOTCH3	Q9UM47-1.2	P713E	Neutral	0.015
NOTCH3	Q9UM47-1.2	P713F	Pathogenic	0.56
NOTCH3	Q9UM47-1.2	P713G	Neutral	0.058
NOTCH3	Q9UM47-1.2	P713H	Neutral	0.061
NOTCH3	Q9UM47-1.2	P713I	Neutral	0.226
NOTCH3	Q9UM47-1.2	P713K	Neutral	0.013
NOTCH3	Q9UM47-1.2	P713L	Neutral	0.226
NOTCH3	Q9UM47-1.2	P713M	Neutral	0.06
NOTCH3	Q9UM47-1.2	P713N	Neutral	0.067
NOTCH3	Q9UM47-1.2	P713Q	Neutral	0.014
NOTCH3	Q9UM47-1.2	P713R	Neutral	0.056
NOTCH3	Q9UM47-1.2	P713S	Neutral	0.015
NOTCH3	Q9UM47-1.2	P713T	Neutral	0.016
NOTCH3	Q9UM47-1.2	P713V	Neutral	0.064
NOTCH3	Q9UM47-1.2	P713W	Pathogenic	0.535
NOTCH3	Q9UM47-1.2	P713Y	Neutral	0.214
NOTCH3	Q9UM47-1.2	G714A	Neutral	0.003
NOTCH3	Q9UM47-1.2	G714C	Neutral	0.181
NOTCH3	Q9UM47-1.2	G714D	Neutral	0.01
NOTCH3	Q9UM47-1.2	G714E	Neutral	0.043
NOTCH3	Q9UM47-1.2	G714F	Neutral	0.156
NOTCH3	Q9UM47-1.2	G714H	Neutral	0.041
NOTCH3	Q9UM47-1.2	G714I	Neutral	0.467
NOTCH3	Q9UM47-1.2	G714K	Neutral	0.039
NOTCH3	Q9UM47-1.2	G714L	Neutral	0.467
NOTCH3	Q9UM47-1.2	G714M	Neutral	0.161
NOTCH3	Q9UM47-1.2	G714N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G714P	Neutral	0.046
NOTCH3	Q9UM47-1.2	G714Q	Neutral	0.042
NOTCH3	Q9UM47-1.2	G714R	Neutral	0.037
NOTCH3	Q9UM47-1.2	G714S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G714T	Neutral	0.045
NOTCH3	Q9UM47-1.2	G714V	Neutral	0.171
NOTCH3	Q9UM47-1.2	G714W	Neutral	0.035
NOTCH3	Q9UM47-1.2	G714Y	Neutral	0.152
NOTCH3	Q9UM47-1.2	G715A	Neutral	0.126
NOTCH3	Q9UM47-1.2	G715C	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	G715D	Neutral	0.376
NOTCH3	Q9UM47-1.2	G715E	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	G715F	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	G715H	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	G715I	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	G715K	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	G715L	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	G715M	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	G715N	Neutral	0.115
NOTCH3	Q9UM47-1.2	G715P	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	G715Q	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	G715R	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	G715S	Neutral	0.124
NOTCH3	Q9UM47-1.2	G715T	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	G715V	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	G715W	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	G715Y	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	F716A	Pathogenic	0.673
NOTCH3	Q9UM47-1.2	F716C	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	F716D	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	F716E	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	F716G	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	F716H	Neutral	0.356
NOTCH3	Q9UM47-1.2	F716I	Neutral	0.109
NOTCH3	Q9UM47-1.2	F716K	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	F716L	Neutral	0.109
NOTCH3	Q9UM47-1.2	F716M	Neutral	0.109
NOTCH3	Q9UM47-1.2	F716N	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	F716P	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	F716Q	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	F716R	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	F716S	Pathogenic	0.679
NOTCH3	Q9UM47-1.2	F716T	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	F716V	Neutral	0.342
NOTCH3	Q9UM47-1.2	F716W	Neutral	0.025
NOTCH3	Q9UM47-1.2	F716Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	R717A	Neutral	0.085
NOTCH3	Q9UM47-1.2	R717C	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	R717D	Neutral	0.315
NOTCH3	Q9UM47-1.2	R717E	Neutral	0.023
NOTCH3	Q9UM47-1.2	R717F	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	R717G	Neutral	0.282
NOTCH3	Q9UM47-1.2	R717H	Neutral	0.024
NOTCH3	Q9UM47-1.2	R717I	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	R717K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R717L	Neutral	0.348
NOTCH3	Q9UM47-1.2	R717M	Neutral	0.105
NOTCH3	Q9UM47-1.2	R717N	Neutral	0.022
NOTCH3	Q9UM47-1.2	R717P	Neutral	0.317
NOTCH3	Q9UM47-1.2	R717Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	R717S	Neutral	0.087
NOTCH3	Q9UM47-1.2	R717T	Neutral	0.093
NOTCH3	Q9UM47-1.2	R717V	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	R717W	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	R717Y	Neutral	0.362
NOTCH3	Q9UM47-1.2	C718A	Pathogenic	0.507
NOTCH3	Q9UM47-1.2	C718D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C718E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C718F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	C718G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C718H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C718I	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C718K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C718L	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C718M	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C718N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C718P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C718Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C718R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C718S	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	C718T	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	C718V	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	C718W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C718Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	V719A	Neutral	0.009
NOTCH3	Q9UM47-1.2	V719C	Neutral	0.043
NOTCH3	Q9UM47-1.2	V719D	Neutral	0.493
NOTCH3	Q9UM47-1.2	V719E	Neutral	0.182
NOTCH3	Q9UM47-1.2	V719F	Neutral	0.042
NOTCH3	Q9UM47-1.2	V719G	Neutral	0.45
NOTCH3	Q9UM47-1.2	V719H	Neutral	0.492
NOTCH3	Q9UM47-1.2	V719I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V719K	Neutral	0.168
NOTCH3	Q9UM47-1.2	V719L	Neutral	0.002
NOTCH3	Q9UM47-1.2	V719M	Neutral	0.002
NOTCH3	Q9UM47-1.2	V719N	Neutral	0.498
NOTCH3	Q9UM47-1.2	V719P	Neutral	0.174
NOTCH3	Q9UM47-1.2	V719Q	Neutral	0.178
NOTCH3	Q9UM47-1.2	V719R	Neutral	0.466
NOTCH3	Q9UM47-1.2	V719S	Neutral	0.165
NOTCH3	Q9UM47-1.2	V719T	Neutral	0.01
NOTCH3	Q9UM47-1.2	V719W	Neutral	0.449
NOTCH3	Q9UM47-1.2	V719Y	Neutral	0.041
NOTCH3	Q9UM47-1.2	C720A	Pathogenic	0.507
NOTCH3	Q9UM47-1.2	C720D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C720E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C720F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	C720G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C720H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C720I	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C720K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C720L	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C720M	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C720N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C720P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C720Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C720R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C720S	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	C720T	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	C720V	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	C720W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C720Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	E721A	Neutral	0.097
NOTCH3	Q9UM47-1.2	E721C	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	E721D	Neutral	0.001
NOTCH3	Q9UM47-1.2	E721F	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	E721G	Neutral	0.312
NOTCH3	Q9UM47-1.2	E721H	Neutral	0.026
NOTCH3	Q9UM47-1.2	E721I	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	E721K	Neutral	0.005
NOTCH3	Q9UM47-1.2	E721L	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	E721M	Neutral	0.353
NOTCH3	Q9UM47-1.2	E721N	Neutral	0.026
NOTCH3	Q9UM47-1.2	E721P	Neutral	0.105
NOTCH3	Q9UM47-1.2	E721Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	E721R	Neutral	0.023
NOTCH3	Q9UM47-1.2	E721S	Neutral	0.023
NOTCH3	Q9UM47-1.2	E721T	Neutral	0.106
NOTCH3	Q9UM47-1.2	E721V	Neutral	0.363
NOTCH3	Q9UM47-1.2	E721W	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	E721Y	Neutral	0.338
NOTCH3	Q9UM47-1.2	P722A	Neutral	0.216
NOTCH3	Q9UM47-1.2	P722C	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	P722D	Neutral	0.233
NOTCH3	Q9UM47-1.2	P722E	Neutral	0.22
NOTCH3	Q9UM47-1.2	P722F	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	P722G	Pathogenic	0.539
NOTCH3	Q9UM47-1.2	P722H	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	P722I	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	P722K	Neutral	0.204
NOTCH3	Q9UM47-1.2	P722L	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	P722M	Pathogenic	0.547
NOTCH3	Q9UM47-1.2	P722N	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	P722Q	Neutral	0.216
NOTCH3	Q9UM47-1.2	P722R	Pathogenic	0.526
NOTCH3	Q9UM47-1.2	P722S	Neutral	0.221
NOTCH3	Q9UM47-1.2	P722T	Neutral	0.23
NOTCH3	Q9UM47-1.2	P722V	Pathogenic	0.565
NOTCH3	Q9UM47-1.2	P722W	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	P722Y	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G723A	Neutral	0.242
NOTCH3	Q9UM47-1.2	G723C	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	G723D	Pathogenic	0.571
NOTCH3	Q9UM47-1.2	G723E	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	G723F	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G723H	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	G723I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G723K	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G723L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G723M	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G723N	Neutral	0.223
NOTCH3	Q9UM47-1.2	G723P	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	G723Q	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	G723R	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	G723S	Neutral	0.238
NOTCH3	Q9UM47-1.2	G723T	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	G723V	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G723W	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	G723Y	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	W724A	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W724C	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W724D	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W724E	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W724F	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	W724G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	W724H	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W724I	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W724K	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W724L	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W724M	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	W724N	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W724P	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W724Q	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W724R	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W724S	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W724T	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W724V	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W724Y	Neutral	0.456
NOTCH3	Q9UM47-1.2	S725A	Neutral	0.008
NOTCH3	Q9UM47-1.2	S725C	Neutral	0.14
NOTCH3	Q9UM47-1.2	S725D	Neutral	0.034
NOTCH3	Q9UM47-1.2	S725E	Neutral	0.032
NOTCH3	Q9UM47-1.2	S725F	Neutral	0.382
NOTCH3	Q9UM47-1.2	S725G	Neutral	0.033
NOTCH3	Q9UM47-1.2	S725H	Neutral	0.125
NOTCH3	Q9UM47-1.2	S725I	Neutral	0.392
NOTCH3	Q9UM47-1.2	S725K	Neutral	0.029
NOTCH3	Q9UM47-1.2	S725L	Neutral	0.392
NOTCH3	Q9UM47-1.2	S725M	Neutral	0.124
NOTCH3	Q9UM47-1.2	S725N	Neutral	0.007
NOTCH3	Q9UM47-1.2	S725P	Neutral	0.138
NOTCH3	Q9UM47-1.2	S725Q	Neutral	0.031
NOTCH3	Q9UM47-1.2	S725R	Neutral	0.114
NOTCH3	Q9UM47-1.2	S725T	Neutral	0.008
NOTCH3	Q9UM47-1.2	S725V	Neutral	0.409
NOTCH3	Q9UM47-1.2	S725W	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	S725Y	Neutral	0.375
NOTCH3	Q9UM47-1.2	G726A	Neutral	0.241
NOTCH3	Q9UM47-1.2	G726C	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	G726D	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	G726E	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	G726F	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G726H	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	G726I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G726K	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	G726L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G726M	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G726N	Neutral	0.222
NOTCH3	Q9UM47-1.2	G726P	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	G726Q	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G726R	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G726S	Neutral	0.237
NOTCH3	Q9UM47-1.2	G726T	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	G726V	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G726W	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	G726Y	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	P727A	Neutral	0.01
NOTCH3	Q9UM47-1.2	P727C	Neutral	0.188
NOTCH3	Q9UM47-1.2	P727D	Neutral	0.011
NOTCH3	Q9UM47-1.2	P727E	Neutral	0.011
NOTCH3	Q9UM47-1.2	P727F	Neutral	0.476
NOTCH3	Q9UM47-1.2	P727G	Neutral	0.042
NOTCH3	Q9UM47-1.2	P727H	Neutral	0.045
NOTCH3	Q9UM47-1.2	P727I	Neutral	0.172
NOTCH3	Q9UM47-1.2	P727K	Neutral	0.01
NOTCH3	Q9UM47-1.2	P727L	Neutral	0.172
NOTCH3	Q9UM47-1.2	P727M	Neutral	0.044
NOTCH3	Q9UM47-1.2	P727N	Neutral	0.049
NOTCH3	Q9UM47-1.2	P727Q	Neutral	0.01
NOTCH3	Q9UM47-1.2	P727R	Neutral	0.04
NOTCH3	Q9UM47-1.2	P727S	Neutral	0.011
NOTCH3	Q9UM47-1.2	P727T	Neutral	0.011
NOTCH3	Q9UM47-1.2	P727V	Neutral	0.047
NOTCH3	Q9UM47-1.2	P727W	Neutral	0.45
NOTCH3	Q9UM47-1.2	P727Y	Neutral	0.162
NOTCH3	Q9UM47-1.2	R728A	Neutral	0.051
NOTCH3	Q9UM47-1.2	R728C	Pathogenic	0.544
NOTCH3	Q9UM47-1.2	R728D	Neutral	0.209
NOTCH3	Q9UM47-1.2	R728E	Neutral	0.013
NOTCH3	Q9UM47-1.2	R728F	Pathogenic	0.592
NOTCH3	Q9UM47-1.2	R728G	Neutral	0.184
NOTCH3	Q9UM47-1.2	R728H	Neutral	0.014
NOTCH3	Q9UM47-1.2	R728I	Pathogenic	0.582
NOTCH3	Q9UM47-1.2	R728K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R728L	Neutral	0.234
NOTCH3	Q9UM47-1.2	R728M	Neutral	0.063
NOTCH3	Q9UM47-1.2	R728N	Neutral	0.013
NOTCH3	Q9UM47-1.2	R728P	Neutral	0.21
NOTCH3	Q9UM47-1.2	R728Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R728S	Neutral	0.052
NOTCH3	Q9UM47-1.2	R728T	Neutral	0.056
NOTCH3	Q9UM47-1.2	R728V	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	R728W	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	R728Y	Neutral	0.245
NOTCH3	Q9UM47-1.2	C729A	Pathogenic	0.507
NOTCH3	Q9UM47-1.2	C729D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C729E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C729F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	C729G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C729H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C729I	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C729K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C729L	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C729M	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C729N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C729P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C729Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C729R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C729S	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	C729T	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	C729V	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	C729W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C729Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	S730A	Neutral	0.002
NOTCH3	Q9UM47-1.2	S730C	Neutral	0.041
NOTCH3	Q9UM47-1.2	S730D	Neutral	0.009
NOTCH3	Q9UM47-1.2	S730E	Neutral	0.008
NOTCH3	Q9UM47-1.2	S730F	Neutral	0.139
NOTCH3	Q9UM47-1.2	S730G	Neutral	0.009
NOTCH3	Q9UM47-1.2	S730H	Neutral	0.036
NOTCH3	Q9UM47-1.2	S730I	Neutral	0.144
NOTCH3	Q9UM47-1.2	S730K	Neutral	0.008
NOTCH3	Q9UM47-1.2	S730L	Neutral	0.144
NOTCH3	Q9UM47-1.2	S730M	Neutral	0.035
NOTCH3	Q9UM47-1.2	S730N	Neutral	0.002
NOTCH3	Q9UM47-1.2	S730P	Neutral	0.04
NOTCH3	Q9UM47-1.2	S730Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	S730R	Neutral	0.032
NOTCH3	Q9UM47-1.2	S730T	Neutral	0.002
NOTCH3	Q9UM47-1.2	S730V	Neutral	0.153
NOTCH3	Q9UM47-1.2	S730W	Neutral	0.398
NOTCH3	Q9UM47-1.2	S730Y	Neutral	0.135
NOTCH3	Q9UM47-1.2	Q731A	Neutral	0.094
NOTCH3	Q9UM47-1.2	Q731C	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	Q731D	Neutral	0.024
NOTCH3	Q9UM47-1.2	Q731E	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q731F	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	Q731G	Neutral	0.304
NOTCH3	Q9UM47-1.2	Q731H	Neutral	0.026
NOTCH3	Q9UM47-1.2	Q731I	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	Q731K	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q731L	Neutral	0.355
NOTCH3	Q9UM47-1.2	Q731M	Neutral	0.026
NOTCH3	Q9UM47-1.2	Q731N	Neutral	0.025
NOTCH3	Q9UM47-1.2	Q731P	Neutral	0.102
NOTCH3	Q9UM47-1.2	Q731R	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q731S	Neutral	0.023
NOTCH3	Q9UM47-1.2	Q731T	Neutral	0.103
NOTCH3	Q9UM47-1.2	Q731V	Neutral	0.355
NOTCH3	Q9UM47-1.2	Q731W	Neutral	0.322
NOTCH3	Q9UM47-1.2	Q731Y	Neutral	0.101
NOTCH3	Q9UM47-1.2	S732A	Neutral	0.003
NOTCH3	Q9UM47-1.2	S732C	Neutral	0.051
NOTCH3	Q9UM47-1.2	S732D	Neutral	0.011
NOTCH3	Q9UM47-1.2	S732E	Neutral	0.011
NOTCH3	Q9UM47-1.2	S732F	Neutral	0.17
NOTCH3	Q9UM47-1.2	S732G	Neutral	0.011
NOTCH3	Q9UM47-1.2	S732H	Neutral	0.045
NOTCH3	Q9UM47-1.2	S732I	Neutral	0.176
NOTCH3	Q9UM47-1.2	S732K	Neutral	0.01
NOTCH3	Q9UM47-1.2	S732L	Neutral	0.176
NOTCH3	Q9UM47-1.2	S732M	Neutral	0.045
NOTCH3	Q9UM47-1.2	S732N	Neutral	0.002
NOTCH3	Q9UM47-1.2	S732P	Neutral	0.05
NOTCH3	Q9UM47-1.2	S732Q	Neutral	0.01
NOTCH3	Q9UM47-1.2	S732R	Neutral	0.041
NOTCH3	Q9UM47-1.2	S732T	Neutral	0.003
NOTCH3	Q9UM47-1.2	S732V	Neutral	0.186
NOTCH3	Q9UM47-1.2	S732W	Neutral	0.456
NOTCH3	Q9UM47-1.2	S732Y	Neutral	0.165
NOTCH3	Q9UM47-1.2	L733A	Neutral	0.028
NOTCH3	Q9UM47-1.2	L733C	Neutral	0.03
NOTCH3	Q9UM47-1.2	L733D	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	L733E	Neutral	0.411
NOTCH3	Q9UM47-1.2	L733F	Neutral	0.007
NOTCH3	Q9UM47-1.2	L733G	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	L733H	Neutral	0.418
NOTCH3	Q9UM47-1.2	L733I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L733K	Neutral	0.135
NOTCH3	Q9UM47-1.2	L733M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L733N	Neutral	0.399
NOTCH3	Q9UM47-1.2	L733P	Neutral	0.391
NOTCH3	Q9UM47-1.2	L733Q	Neutral	0.135
NOTCH3	Q9UM47-1.2	L733R	Neutral	0.129
NOTCH3	Q9UM47-1.2	L733S	Neutral	0.117
NOTCH3	Q9UM47-1.2	L733T	Neutral	0.03
NOTCH3	Q9UM47-1.2	L733V	Neutral	0.002
NOTCH3	Q9UM47-1.2	L733W	Neutral	0.121
NOTCH3	Q9UM47-1.2	L733Y	Neutral	0.032
NOTCH3	Q9UM47-1.2	A734C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A734D	Neutral	0.057
NOTCH3	Q9UM47-1.2	A734E	Neutral	0.012
NOTCH3	Q9UM47-1.2	A734F	Neutral	0.048
NOTCH3	Q9UM47-1.2	A734G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A734H	Neutral	0.051
NOTCH3	Q9UM47-1.2	A734I	Neutral	0.012
NOTCH3	Q9UM47-1.2	A734K	Neutral	0.011
NOTCH3	Q9UM47-1.2	A734L	Neutral	0.012
NOTCH3	Q9UM47-1.2	A734M	Neutral	0.011
NOTCH3	Q9UM47-1.2	A734N	Neutral	0.056
NOTCH3	Q9UM47-1.2	A734P	Neutral	0.013
NOTCH3	Q9UM47-1.2	A734Q	Neutral	0.012
NOTCH3	Q9UM47-1.2	A734R	Neutral	0.011
NOTCH3	Q9UM47-1.2	A734S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A734T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A734V	Neutral	0.003
NOTCH3	Q9UM47-1.2	A734W	Neutral	0.173
NOTCH3	Q9UM47-1.2	A734Y	Neutral	0.047
NOTCH3	Q9UM47-1.2	R735A	Neutral	0.038
NOTCH3	Q9UM47-1.2	R735C	Neutral	0.47
NOTCH3	Q9UM47-1.2	R735D	Neutral	0.164
NOTCH3	Q9UM47-1.2	R735E	Neutral	0.01
NOTCH3	Q9UM47-1.2	R735F	Pathogenic	0.519
NOTCH3	Q9UM47-1.2	R735G	Neutral	0.143
NOTCH3	Q9UM47-1.2	R735H	Neutral	0.01
NOTCH3	Q9UM47-1.2	R735I	Pathogenic	0.508
NOTCH3	Q9UM47-1.2	R735K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R735L	Neutral	0.185
NOTCH3	Q9UM47-1.2	R735M	Neutral	0.047
NOTCH3	Q9UM47-1.2	R735N	Neutral	0.01
NOTCH3	Q9UM47-1.2	R735P	Neutral	0.165
NOTCH3	Q9UM47-1.2	R735Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	R735S	Neutral	0.039
NOTCH3	Q9UM47-1.2	R735T	Neutral	0.042
NOTCH3	Q9UM47-1.2	R735V	Neutral	0.489
NOTCH3	Q9UM47-1.2	R735W	Pathogenic	0.518
NOTCH3	Q9UM47-1.2	R735Y	Neutral	0.194
NOTCH3	Q9UM47-1.2	D736A	Neutral	0.397
NOTCH3	Q9UM47-1.2	D736C	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	D736E	Neutral	0.002
NOTCH3	Q9UM47-1.2	D736F	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	D736G	Neutral	0.118
NOTCH3	Q9UM47-1.2	D736H	Neutral	0.125
NOTCH3	Q9UM47-1.2	D736I	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	D736K	Neutral	0.117
NOTCH3	Q9UM47-1.2	D736L	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	D736M	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	D736N	Neutral	0.007
NOTCH3	Q9UM47-1.2	D736P	Neutral	0.137
NOTCH3	Q9UM47-1.2	D736Q	Neutral	0.031
NOTCH3	Q9UM47-1.2	D736R	Neutral	0.365
NOTCH3	Q9UM47-1.2	D736S	Neutral	0.031
NOTCH3	Q9UM47-1.2	D736T	Neutral	0.136
NOTCH3	Q9UM47-1.2	D736V	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	D736W	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	D736Y	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	A737C	Neutral	0.01
NOTCH3	Q9UM47-1.2	A737D	Neutral	0.174
NOTCH3	Q9UM47-1.2	A737E	Neutral	0.041
NOTCH3	Q9UM47-1.2	A737F	Neutral	0.152
NOTCH3	Q9UM47-1.2	A737G	Neutral	0.01
NOTCH3	Q9UM47-1.2	A737H	Neutral	0.159
NOTCH3	Q9UM47-1.2	A737I	Neutral	0.039
NOTCH3	Q9UM47-1.2	A737K	Neutral	0.038
NOTCH3	Q9UM47-1.2	A737L	Neutral	0.039
NOTCH3	Q9UM47-1.2	A737M	Neutral	0.039
NOTCH3	Q9UM47-1.2	A737N	Neutral	0.171
NOTCH3	Q9UM47-1.2	A737P	Neutral	0.044
NOTCH3	Q9UM47-1.2	A737Q	Neutral	0.041
NOTCH3	Q9UM47-1.2	A737R	Neutral	0.036
NOTCH3	Q9UM47-1.2	A737S	Neutral	0.002
NOTCH3	Q9UM47-1.2	A737T	Neutral	0.01
NOTCH3	Q9UM47-1.2	A737V	Neutral	0.01
NOTCH3	Q9UM47-1.2	A737W	Neutral	0.423
NOTCH3	Q9UM47-1.2	A737Y	Neutral	0.148
NOTCH3	Q9UM47-1.2	C738A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C738D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C738E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C738F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C738G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C738H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C738I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C738K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C738L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C738M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C738N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C738P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C738Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C738R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C738S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C738T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C738V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C738W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C738Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	E739A	Neutral	0.207
NOTCH3	Q9UM47-1.2	E739C	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	E739D	Neutral	0.003
NOTCH3	Q9UM47-1.2	E739F	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	E739G	Pathogenic	0.524
NOTCH3	Q9UM47-1.2	E739H	Neutral	0.061
NOTCH3	Q9UM47-1.2	E739I	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	E739K	Neutral	0.013
NOTCH3	Q9UM47-1.2	E739L	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	E739M	Pathogenic	0.571
NOTCH3	Q9UM47-1.2	E739N	Neutral	0.06
NOTCH3	Q9UM47-1.2	E739P	Neutral	0.223
NOTCH3	Q9UM47-1.2	E739Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	E739R	Neutral	0.055
NOTCH3	Q9UM47-1.2	E739S	Neutral	0.055
NOTCH3	Q9UM47-1.2	E739T	Neutral	0.224
NOTCH3	Q9UM47-1.2	E739V	Pathogenic	0.581
NOTCH3	Q9UM47-1.2	E739W	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	E739Y	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	S740A	Neutral	0.069
NOTCH3	Q9UM47-1.2	S740C	Pathogenic	0.599
NOTCH3	Q9UM47-1.2	S740D	Neutral	0.243
NOTCH3	Q9UM47-1.2	S740E	Neutral	0.23
NOTCH3	Q9UM47-1.2	S740F	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	S740G	Neutral	0.237
NOTCH3	Q9UM47-1.2	S740H	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	S740I	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	S740K	Neutral	0.214
NOTCH3	Q9UM47-1.2	S740L	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	S740M	Pathogenic	0.564
NOTCH3	Q9UM47-1.2	S740N	Neutral	0.065
NOTCH3	Q9UM47-1.2	S740P	Pathogenic	0.595
NOTCH3	Q9UM47-1.2	S740Q	Neutral	0.226
NOTCH3	Q9UM47-1.2	S740R	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	S740T	Neutral	0.065
NOTCH3	Q9UM47-1.2	S740V	Pathogenic	0.864
NOTCH3	Q9UM47-1.2	S740W	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	S740Y	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	Q741A	Neutral	0.047
NOTCH3	Q9UM47-1.2	Q741C	Pathogenic	0.528
NOTCH3	Q9UM47-1.2	Q741D	Neutral	0.012
NOTCH3	Q9UM47-1.2	Q741E	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q741F	Pathogenic	0.536
NOTCH3	Q9UM47-1.2	Q741G	Neutral	0.174
NOTCH3	Q9UM47-1.2	Q741H	Neutral	0.013
NOTCH3	Q9UM47-1.2	Q741I	Pathogenic	0.546
NOTCH3	Q9UM47-1.2	Q741K	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q741L	Neutral	0.209
NOTCH3	Q9UM47-1.2	Q741M	Neutral	0.013
NOTCH3	Q9UM47-1.2	Q741N	Neutral	0.012
NOTCH3	Q9UM47-1.2	Q741P	Neutral	0.052
NOTCH3	Q9UM47-1.2	Q741R	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q741S	Neutral	0.011
NOTCH3	Q9UM47-1.2	Q741T	Neutral	0.052
NOTCH3	Q9UM47-1.2	Q741V	Neutral	0.209
NOTCH3	Q9UM47-1.2	Q741W	Neutral	0.186
NOTCH3	Q9UM47-1.2	Q741Y	Neutral	0.051
NOTCH3	Q9UM47-1.2	P742A	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	P742C	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	P742D	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	P742E	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	P742F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P742G	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	P742H	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	P742I	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	P742K	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	P742L	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	P742M	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	P742N	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	P742Q	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	P742R	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	P742S	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	P742T	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	P742V	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	P742W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P742Y	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	C743A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C743D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C743E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C743F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C743G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C743H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C743I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C743K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C743L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C743M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C743N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C743P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C743Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C743R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C743S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C743T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C743V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C743W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C743Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	R744A	Neutral	0.015
NOTCH3	Q9UM47-1.2	R744C	Neutral	0.25
NOTCH3	Q9UM47-1.2	R744D	Neutral	0.068
NOTCH3	Q9UM47-1.2	R744E	Neutral	0.004
NOTCH3	Q9UM47-1.2	R744F	Neutral	0.288
NOTCH3	Q9UM47-1.2	R744G	Neutral	0.059
NOTCH3	Q9UM47-1.2	R744H	Neutral	0.004
NOTCH3	Q9UM47-1.2	R744I	Neutral	0.28
NOTCH3	Q9UM47-1.2	R744K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R744L	Neutral	0.079
NOTCH3	Q9UM47-1.2	R744M	Neutral	0.018
NOTCH3	Q9UM47-1.2	R744N	Neutral	0.004
NOTCH3	Q9UM47-1.2	R744P	Neutral	0.069
NOTCH3	Q9UM47-1.2	R744Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	R744S	Neutral	0.015
NOTCH3	Q9UM47-1.2	R744T	Neutral	0.016
NOTCH3	Q9UM47-1.2	R744V	Neutral	0.264
NOTCH3	Q9UM47-1.2	R744W	Neutral	0.287
NOTCH3	Q9UM47-1.2	R744Y	Neutral	0.083
NOTCH3	Q9UM47-1.2	A745C	Neutral	0.005
NOTCH3	Q9UM47-1.2	A745D	Neutral	0.092
NOTCH3	Q9UM47-1.2	A745E	Neutral	0.02
NOTCH3	Q9UM47-1.2	A745F	Neutral	0.079
NOTCH3	Q9UM47-1.2	A745G	Neutral	0.005
NOTCH3	Q9UM47-1.2	A745H	Neutral	0.083
NOTCH3	Q9UM47-1.2	A745I	Neutral	0.019
NOTCH3	Q9UM47-1.2	A745K	Neutral	0.018
NOTCH3	Q9UM47-1.2	A745L	Neutral	0.019
NOTCH3	Q9UM47-1.2	A745M	Neutral	0.019
NOTCH3	Q9UM47-1.2	A745N	Neutral	0.09
NOTCH3	Q9UM47-1.2	A745P	Neutral	0.022
NOTCH3	Q9UM47-1.2	A745Q	Neutral	0.02
NOTCH3	Q9UM47-1.2	A745R	Neutral	0.018
NOTCH3	Q9UM47-1.2	A745S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A745T	Neutral	0.005
NOTCH3	Q9UM47-1.2	A745V	Neutral	0.005
NOTCH3	Q9UM47-1.2	A745W	Neutral	0.26
NOTCH3	Q9UM47-1.2	A745Y	Neutral	0.077
NOTCH3	Q9UM47-1.2	G746A	Neutral	0.146
NOTCH3	Q9UM47-1.2	G746C	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	G746D	Neutral	0.416
NOTCH3	Q9UM47-1.2	G746E	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	G746F	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	G746H	Pathogenic	0.744
NOTCH3	Q9UM47-1.2	G746I	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	G746K	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	G746L	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	G746M	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	G746N	Neutral	0.133
NOTCH3	Q9UM47-1.2	G746P	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	G746Q	Pathogenic	0.747
NOTCH3	Q9UM47-1.2	G746R	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	G746S	Neutral	0.143
NOTCH3	Q9UM47-1.2	G746T	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	G746V	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	G746W	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	G746Y	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	G747A	Neutral	0.213
NOTCH3	Q9UM47-1.2	G747C	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G747D	Pathogenic	0.53
NOTCH3	Q9UM47-1.2	G747E	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	G747F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	G747H	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	G747I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G747K	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	G747L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G747M	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G747N	Neutral	0.195
NOTCH3	Q9UM47-1.2	G747P	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G747Q	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G747R	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	G747S	Neutral	0.208
NOTCH3	Q9UM47-1.2	G747T	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G747V	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G747W	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	G747Y	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	T748A	Neutral	0.216
NOTCH3	Q9UM47-1.2	T748C	Pathogenic	0.576
NOTCH3	Q9UM47-1.2	T748D	Pathogenic	0.581
NOTCH3	Q9UM47-1.2	T748E	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	T748F	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	T748G	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	T748H	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	T748I	Pathogenic	0.555
NOTCH3	Q9UM47-1.2	T748K	Pathogenic	0.543
NOTCH3	Q9UM47-1.2	T748L	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	T748M	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	T748N	Neutral	0.232
NOTCH3	Q9UM47-1.2	T748P	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	T748Q	Pathogenic	0.562
NOTCH3	Q9UM47-1.2	T748R	Pathogenic	0.531
NOTCH3	Q9UM47-1.2	T748S	Neutral	0.058
NOTCH3	Q9UM47-1.2	T748V	Neutral	0.226
NOTCH3	Q9UM47-1.2	T748W	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	T748Y	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	C749A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C749D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C749E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C749F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C749G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C749H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C749I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C749K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C749L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C749M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C749N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C749P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C749Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C749R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C749S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C749T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C749V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C749W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C749Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	S750A	Neutral	0.0
NOTCH3	Q9UM47-1.2	S750C	Neutral	0.001
NOTCH3	Q9UM47-1.2	S750D	Neutral	0.0
NOTCH3	Q9UM47-1.2	S750E	Neutral	0.0
NOTCH3	Q9UM47-1.2	S750F	Neutral	0.003
NOTCH3	Q9UM47-1.2	S750G	Neutral	0.0
NOTCH3	Q9UM47-1.2	S750H	Neutral	0.001
NOTCH3	Q9UM47-1.2	S750I	Neutral	0.003
NOTCH3	Q9UM47-1.2	S750K	Neutral	0.0
NOTCH3	Q9UM47-1.2	S750L	Neutral	0.003
NOTCH3	Q9UM47-1.2	S750M	Neutral	0.001
NOTCH3	Q9UM47-1.2	S750N	Neutral	0.0
NOTCH3	Q9UM47-1.2	S750P	Neutral	0.001
NOTCH3	Q9UM47-1.2	S750Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	S750R	Neutral	0.001
NOTCH3	Q9UM47-1.2	S750T	Neutral	0.0
NOTCH3	Q9UM47-1.2	S750V	Neutral	0.003
NOTCH3	Q9UM47-1.2	S750W	Neutral	0.011
NOTCH3	Q9UM47-1.2	S750Y	Neutral	0.003
NOTCH3	Q9UM47-1.2	S751A	Neutral	0.002
NOTCH3	Q9UM47-1.2	S751C	Neutral	0.034
NOTCH3	Q9UM47-1.2	S751D	Neutral	0.007
NOTCH3	Q9UM47-1.2	S751E	Neutral	0.007
NOTCH3	Q9UM47-1.2	S751F	Neutral	0.117
NOTCH3	Q9UM47-1.2	S751G	Neutral	0.007
NOTCH3	Q9UM47-1.2	S751H	Neutral	0.03
NOTCH3	Q9UM47-1.2	S751I	Neutral	0.122
NOTCH3	Q9UM47-1.2	S751K	Neutral	0.006
NOTCH3	Q9UM47-1.2	S751L	Neutral	0.122
NOTCH3	Q9UM47-1.2	S751M	Neutral	0.029
NOTCH3	Q9UM47-1.2	S751N	Neutral	0.002
NOTCH3	Q9UM47-1.2	S751P	Neutral	0.033
NOTCH3	Q9UM47-1.2	S751Q	Neutral	0.007
NOTCH3	Q9UM47-1.2	S751R	Neutral	0.027
NOTCH3	Q9UM47-1.2	S751T	Neutral	0.002
NOTCH3	Q9UM47-1.2	S751V	Neutral	0.129
NOTCH3	Q9UM47-1.2	S751W	Neutral	0.353
NOTCH3	Q9UM47-1.2	S751Y	Neutral	0.114
NOTCH3	Q9UM47-1.2	D752A	Neutral	0.059
NOTCH3	Q9UM47-1.2	D752C	Neutral	0.235
NOTCH3	Q9UM47-1.2	D752E	Neutral	0.0
NOTCH3	Q9UM47-1.2	D752F	Neutral	0.21
NOTCH3	Q9UM47-1.2	D752G	Neutral	0.013
NOTCH3	Q9UM47-1.2	D752H	Neutral	0.013
NOTCH3	Q9UM47-1.2	D752I	Neutral	0.217
NOTCH3	Q9UM47-1.2	D752K	Neutral	0.012
NOTCH3	Q9UM47-1.2	D752L	Pathogenic	0.558
NOTCH3	Q9UM47-1.2	D752M	Neutral	0.217
NOTCH3	Q9UM47-1.2	D752N	Neutral	0.001
NOTCH3	Q9UM47-1.2	D752P	Neutral	0.015
NOTCH3	Q9UM47-1.2	D752Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	D752R	Neutral	0.052
NOTCH3	Q9UM47-1.2	D752S	Neutral	0.003
NOTCH3	Q9UM47-1.2	D752T	Neutral	0.015
NOTCH3	Q9UM47-1.2	D752V	Neutral	0.229
NOTCH3	Q9UM47-1.2	D752W	Pathogenic	0.522
NOTCH3	Q9UM47-1.2	D752Y	Neutral	0.205
NOTCH3	Q9UM47-1.2	G753A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G753C	Neutral	0.134
NOTCH3	Q9UM47-1.2	G753D	Neutral	0.007
NOTCH3	Q9UM47-1.2	G753E	Neutral	0.03
NOTCH3	Q9UM47-1.2	G753F	Neutral	0.114
NOTCH3	Q9UM47-1.2	G753H	Neutral	0.029
NOTCH3	Q9UM47-1.2	G753I	Neutral	0.38
NOTCH3	Q9UM47-1.2	G753K	Neutral	0.027
NOTCH3	Q9UM47-1.2	G753L	Neutral	0.38
NOTCH3	Q9UM47-1.2	G753M	Neutral	0.118
NOTCH3	Q9UM47-1.2	G753N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G753P	Neutral	0.032
NOTCH3	Q9UM47-1.2	G753Q	Neutral	0.029
NOTCH3	Q9UM47-1.2	G753R	Neutral	0.026
NOTCH3	Q9UM47-1.2	G753S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G753T	Neutral	0.032
NOTCH3	Q9UM47-1.2	G753V	Neutral	0.126
NOTCH3	Q9UM47-1.2	G753W	Neutral	0.025
NOTCH3	Q9UM47-1.2	G753Y	Neutral	0.111
NOTCH3	Q9UM47-1.2	M754A	Neutral	0.064
NOTCH3	Q9UM47-1.2	M754C	Neutral	0.068
NOTCH3	Q9UM47-1.2	M754D	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	M754E	Neutral	0.27
NOTCH3	Q9UM47-1.2	M754F	Neutral	0.018
NOTCH3	Q9UM47-1.2	M754G	Pathogenic	0.569
NOTCH3	Q9UM47-1.2	M754H	Neutral	0.275
NOTCH3	Q9UM47-1.2	M754I	Neutral	0.004
NOTCH3	Q9UM47-1.2	M754K	Neutral	0.076
NOTCH3	Q9UM47-1.2	M754L	Neutral	0.001
NOTCH3	Q9UM47-1.2	M754N	Neutral	0.26
NOTCH3	Q9UM47-1.2	M754P	Neutral	0.253
NOTCH3	Q9UM47-1.2	M754Q	Neutral	0.018
NOTCH3	Q9UM47-1.2	M754R	Neutral	0.073
NOTCH3	Q9UM47-1.2	M754S	Neutral	0.066
NOTCH3	Q9UM47-1.2	M754T	Neutral	0.07
NOTCH3	Q9UM47-1.2	M754V	Neutral	0.004
NOTCH3	Q9UM47-1.2	M754W	Neutral	0.068
NOTCH3	Q9UM47-1.2	M754Y	Neutral	0.074
NOTCH3	Q9UM47-1.2	G755A	Neutral	0.117
NOTCH3	Q9UM47-1.2	G755C	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	G755D	Neutral	0.356
NOTCH3	Q9UM47-1.2	G755E	Pathogenic	0.701
NOTCH3	Q9UM47-1.2	G755F	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	G755H	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	G755I	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	G755K	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	G755L	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	G755M	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	G755N	Neutral	0.106
NOTCH3	Q9UM47-1.2	G755P	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	G755Q	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	G755R	Pathogenic	0.669
NOTCH3	Q9UM47-1.2	G755S	Neutral	0.114
NOTCH3	Q9UM47-1.2	G755T	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	G755V	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	G755W	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	G755Y	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	F756A	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	F756C	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	F756D	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	F756E	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	F756G	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	F756H	Neutral	0.413
NOTCH3	Q9UM47-1.2	F756I	Neutral	0.135
NOTCH3	Q9UM47-1.2	F756K	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	F756L	Neutral	0.135
NOTCH3	Q9UM47-1.2	F756M	Neutral	0.135
NOTCH3	Q9UM47-1.2	F756N	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	F756P	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	F756Q	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	F756R	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	F756S	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	F756T	Pathogenic	0.744
NOTCH3	Q9UM47-1.2	F756V	Neutral	0.399
NOTCH3	Q9UM47-1.2	F756W	Neutral	0.031
NOTCH3	Q9UM47-1.2	F756Y	Neutral	0.002
NOTCH3	Q9UM47-1.2	H757A	Neutral	0.168
NOTCH3	Q9UM47-1.2	H757C	Neutral	0.498
NOTCH3	Q9UM47-1.2	H757D	Neutral	0.047
NOTCH3	Q9UM47-1.2	H757E	Neutral	0.011
NOTCH3	Q9UM47-1.2	H757F	Neutral	0.049
NOTCH3	Q9UM47-1.2	H757G	Neutral	0.158
NOTCH3	Q9UM47-1.2	H757I	Pathogenic	0.525
NOTCH3	Q9UM47-1.2	H757K	Neutral	0.048
NOTCH3	Q9UM47-1.2	H757L	Pathogenic	0.525
NOTCH3	Q9UM47-1.2	H757M	Neutral	0.195
NOTCH3	Q9UM47-1.2	H757N	Neutral	0.002
NOTCH3	Q9UM47-1.2	H757P	Neutral	0.181
NOTCH3	Q9UM47-1.2	H757Q	Neutral	0.012
NOTCH3	Q9UM47-1.2	H757R	Neutral	0.011
NOTCH3	Q9UM47-1.2	H757S	Neutral	0.043
NOTCH3	Q9UM47-1.2	H757T	Neutral	0.182
NOTCH3	Q9UM47-1.2	H757V	Pathogenic	0.517
NOTCH3	Q9UM47-1.2	H757W	Neutral	0.173
NOTCH3	Q9UM47-1.2	H757Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	C758A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C758D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C758E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C758F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C758G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C758H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C758I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C758K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C758L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C758M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C758N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C758P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C758Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C758R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C758S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C758T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C758V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C758W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C758Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	T759A	Neutral	0.104
NOTCH3	Q9UM47-1.2	T759C	Neutral	0.364
NOTCH3	Q9UM47-1.2	T759D	Neutral	0.369
NOTCH3	Q9UM47-1.2	T759E	Neutral	0.356
NOTCH3	Q9UM47-1.2	T759F	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	T759G	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	T759H	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	T759I	Neutral	0.344
NOTCH3	Q9UM47-1.2	T759K	Neutral	0.334
NOTCH3	Q9UM47-1.2	T759L	Neutral	0.344
NOTCH3	Q9UM47-1.2	T759M	Neutral	0.343
NOTCH3	Q9UM47-1.2	T759N	Neutral	0.113
NOTCH3	Q9UM47-1.2	T759P	Neutral	0.367
NOTCH3	Q9UM47-1.2	T759Q	Neutral	0.351
NOTCH3	Q9UM47-1.2	T759R	Neutral	0.323
NOTCH3	Q9UM47-1.2	T759S	Neutral	0.025
NOTCH3	Q9UM47-1.2	T759V	Neutral	0.11
NOTCH3	Q9UM47-1.2	T759W	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	T759Y	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	C760A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C760D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C760E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C760F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C760G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C760H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C760I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C760K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C760L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C760M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C760N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C760P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C760Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C760R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C760S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C760T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C760V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C760W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C760Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	P761A	Neutral	0.012
NOTCH3	Q9UM47-1.2	P761C	Neutral	0.208
NOTCH3	Q9UM47-1.2	P761D	Neutral	0.013
NOTCH3	Q9UM47-1.2	P761E	Neutral	0.012
NOTCH3	Q9UM47-1.2	P761F	Pathogenic	0.506
NOTCH3	Q9UM47-1.2	P761G	Neutral	0.048
NOTCH3	Q9UM47-1.2	P761H	Neutral	0.05
NOTCH3	Q9UM47-1.2	P761I	Neutral	0.19
NOTCH3	Q9UM47-1.2	P761K	Neutral	0.011
NOTCH3	Q9UM47-1.2	P761L	Neutral	0.19
NOTCH3	Q9UM47-1.2	P761M	Neutral	0.049
NOTCH3	Q9UM47-1.2	P761N	Neutral	0.054
NOTCH3	Q9UM47-1.2	P761Q	Neutral	0.012
NOTCH3	Q9UM47-1.2	P761R	Neutral	0.045
NOTCH3	Q9UM47-1.2	P761S	Neutral	0.012
NOTCH3	Q9UM47-1.2	P761T	Neutral	0.013
NOTCH3	Q9UM47-1.2	P761V	Neutral	0.052
NOTCH3	Q9UM47-1.2	P761W	Neutral	0.48
NOTCH3	Q9UM47-1.2	P761Y	Neutral	0.179
NOTCH3	Q9UM47-1.2	P762A	Neutral	0.016
NOTCH3	Q9UM47-1.2	P762C	Neutral	0.269
NOTCH3	Q9UM47-1.2	P762D	Neutral	0.018
NOTCH3	Q9UM47-1.2	P762E	Neutral	0.017
NOTCH3	Q9UM47-1.2	P762F	Pathogenic	0.59
NOTCH3	Q9UM47-1.2	P762G	Neutral	0.066
NOTCH3	Q9UM47-1.2	P762H	Neutral	0.069
NOTCH3	Q9UM47-1.2	P762I	Neutral	0.248
NOTCH3	Q9UM47-1.2	P762K	Neutral	0.015
NOTCH3	Q9UM47-1.2	P762L	Neutral	0.248
NOTCH3	Q9UM47-1.2	P762M	Neutral	0.067
NOTCH3	Q9UM47-1.2	P762N	Neutral	0.075
NOTCH3	Q9UM47-1.2	P762Q	Neutral	0.016
NOTCH3	Q9UM47-1.2	P762R	Neutral	0.062
NOTCH3	Q9UM47-1.2	P762S	Neutral	0.017
NOTCH3	Q9UM47-1.2	P762T	Neutral	0.018
NOTCH3	Q9UM47-1.2	P762V	Neutral	0.072
NOTCH3	Q9UM47-1.2	P762W	Pathogenic	0.565
NOTCH3	Q9UM47-1.2	P762Y	Neutral	0.235
NOTCH3	Q9UM47-1.2	G763A	Neutral	0.249
NOTCH3	Q9UM47-1.2	G763C	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	G763D	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	G763E	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	G763F	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G763H	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	G763I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G763K	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	G763L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G763M	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	G763N	Neutral	0.229
NOTCH3	Q9UM47-1.2	G763P	Pathogenic	0.863
NOTCH3	Q9UM47-1.2	G763Q	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	G763R	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G763S	Neutral	0.244
NOTCH3	Q9UM47-1.2	G763T	Pathogenic	0.861
NOTCH3	Q9UM47-1.2	G763V	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G763W	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	G763Y	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	V764A	Neutral	0.009
NOTCH3	Q9UM47-1.2	V764C	Neutral	0.042
NOTCH3	Q9UM47-1.2	V764D	Neutral	0.485
NOTCH3	Q9UM47-1.2	V764E	Neutral	0.177
NOTCH3	Q9UM47-1.2	V764F	Neutral	0.04
NOTCH3	Q9UM47-1.2	V764G	Neutral	0.442
NOTCH3	Q9UM47-1.2	V764H	Neutral	0.484
NOTCH3	Q9UM47-1.2	V764I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V764K	Neutral	0.163
NOTCH3	Q9UM47-1.2	V764L	Neutral	0.002
NOTCH3	Q9UM47-1.2	V764M	Neutral	0.002
NOTCH3	Q9UM47-1.2	V764N	Neutral	0.489
NOTCH3	Q9UM47-1.2	V764P	Neutral	0.169
NOTCH3	Q9UM47-1.2	V764Q	Neutral	0.173
NOTCH3	Q9UM47-1.2	V764R	Neutral	0.457
NOTCH3	Q9UM47-1.2	V764S	Neutral	0.161
NOTCH3	Q9UM47-1.2	V764T	Neutral	0.01
NOTCH3	Q9UM47-1.2	V764W	Neutral	0.44
NOTCH3	Q9UM47-1.2	V764Y	Neutral	0.039
NOTCH3	Q9UM47-1.2	Q765A	Neutral	0.03
NOTCH3	Q9UM47-1.2	Q765C	Neutral	0.407
NOTCH3	Q9UM47-1.2	Q765D	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q765E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q765F	Neutral	0.415
NOTCH3	Q9UM47-1.2	Q765G	Neutral	0.114
NOTCH3	Q9UM47-1.2	Q765H	Neutral	0.008
NOTCH3	Q9UM47-1.2	Q765I	Neutral	0.425
NOTCH3	Q9UM47-1.2	Q765K	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q765L	Neutral	0.14
NOTCH3	Q9UM47-1.2	Q765M	Neutral	0.008
NOTCH3	Q9UM47-1.2	Q765N	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q765P	Neutral	0.032
NOTCH3	Q9UM47-1.2	Q765R	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q765S	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q765T	Neutral	0.033
NOTCH3	Q9UM47-1.2	Q765V	Neutral	0.14
NOTCH3	Q9UM47-1.2	Q765W	Neutral	0.123
NOTCH3	Q9UM47-1.2	Q765Y	Neutral	0.032
NOTCH3	Q9UM47-1.2	G766A	Neutral	0.231
NOTCH3	Q9UM47-1.2	G766C	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G766D	Pathogenic	0.555
NOTCH3	Q9UM47-1.2	G766E	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	G766F	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G766H	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	G766I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G766K	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	G766L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G766M	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G766N	Neutral	0.212
NOTCH3	Q9UM47-1.2	G766P	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	G766Q	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	G766R	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	G766S	Neutral	0.226
NOTCH3	Q9UM47-1.2	G766T	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	G766V	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G766W	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	G766Y	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	R767A	Neutral	0.024
NOTCH3	Q9UM47-1.2	R767C	Neutral	0.356
NOTCH3	Q9UM47-1.2	R767D	Neutral	0.109
NOTCH3	Q9UM47-1.2	R767E	Neutral	0.006
NOTCH3	Q9UM47-1.2	R767F	Neutral	0.402
NOTCH3	Q9UM47-1.2	R767G	Neutral	0.094
NOTCH3	Q9UM47-1.2	R767H	Neutral	0.007
NOTCH3	Q9UM47-1.2	R767I	Neutral	0.392
NOTCH3	Q9UM47-1.2	R767K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R767L	Neutral	0.124
NOTCH3	Q9UM47-1.2	R767M	Neutral	0.03
NOTCH3	Q9UM47-1.2	R767N	Neutral	0.006
NOTCH3	Q9UM47-1.2	R767P	Neutral	0.109
NOTCH3	Q9UM47-1.2	R767Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	R767S	Neutral	0.025
NOTCH3	Q9UM47-1.2	R767T	Neutral	0.026
NOTCH3	Q9UM47-1.2	R767V	Neutral	0.373
NOTCH3	Q9UM47-1.2	R767W	Neutral	0.401
NOTCH3	Q9UM47-1.2	R767Y	Neutral	0.13
NOTCH3	Q9UM47-1.2	Q768A	Neutral	0.022
NOTCH3	Q9UM47-1.2	Q768C	Neutral	0.337
NOTCH3	Q9UM47-1.2	Q768D	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q768E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q768F	Neutral	0.345
NOTCH3	Q9UM47-1.2	Q768G	Neutral	0.087
NOTCH3	Q9UM47-1.2	Q768H	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q768I	Neutral	0.354
NOTCH3	Q9UM47-1.2	Q768K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q768L	Neutral	0.108
NOTCH3	Q9UM47-1.2	Q768M	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q768N	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q768P	Neutral	0.024
NOTCH3	Q9UM47-1.2	Q768R	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q768S	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q768T	Neutral	0.024
NOTCH3	Q9UM47-1.2	Q768V	Neutral	0.108
NOTCH3	Q9UM47-1.2	Q768W	Neutral	0.094
NOTCH3	Q9UM47-1.2	Q768Y	Neutral	0.024
NOTCH3	Q9UM47-1.2	C769A	Neutral	0.456
NOTCH3	Q9UM47-1.2	C769D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C769E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C769F	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	C769G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C769H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C769I	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	C769K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C769L	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	C769M	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	C769N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C769P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C769Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C769R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C769S	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	C769T	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	C769V	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	C769W	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	C769Y	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	E770A	Neutral	0.355
NOTCH3	Q9UM47-1.2	E770C	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	E770D	Neutral	0.006
NOTCH3	Q9UM47-1.2	E770F	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	E770G	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	E770H	Neutral	0.121
NOTCH3	Q9UM47-1.2	E770I	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	E770K	Neutral	0.027
NOTCH3	Q9UM47-1.2	E770L	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	E770M	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	E770N	Neutral	0.118
NOTCH3	Q9UM47-1.2	E770P	Neutral	0.376
NOTCH3	Q9UM47-1.2	E770Q	Neutral	0.007
NOTCH3	Q9UM47-1.2	E770R	Neutral	0.109
NOTCH3	Q9UM47-1.2	E770S	Neutral	0.11
NOTCH3	Q9UM47-1.2	E770T	Neutral	0.378
NOTCH3	Q9UM47-1.2	E770V	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	E770W	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	E770Y	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	L771A	Neutral	0.037
NOTCH3	Q9UM47-1.2	L771C	Neutral	0.04
NOTCH3	Q9UM47-1.2	L771D	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	L771E	Neutral	0.486
NOTCH3	Q9UM47-1.2	L771F	Neutral	0.01
NOTCH3	Q9UM47-1.2	L771G	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	L771H	Neutral	0.493
NOTCH3	Q9UM47-1.2	L771I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L771K	Neutral	0.175
NOTCH3	Q9UM47-1.2	L771M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L771N	Neutral	0.474
NOTCH3	Q9UM47-1.2	L771P	Neutral	0.465
NOTCH3	Q9UM47-1.2	L771Q	Neutral	0.174
NOTCH3	Q9UM47-1.2	L771R	Neutral	0.168
NOTCH3	Q9UM47-1.2	L771S	Neutral	0.153
NOTCH3	Q9UM47-1.2	L771T	Neutral	0.041
NOTCH3	Q9UM47-1.2	L771V	Neutral	0.002
NOTCH3	Q9UM47-1.2	L771W	Neutral	0.157
NOTCH3	Q9UM47-1.2	L771Y	Neutral	0.043
NOTCH3	Q9UM47-1.2	L772A	Neutral	0.386
NOTCH3	Q9UM47-1.2	L772C	Neutral	0.402
NOTCH3	Q9UM47-1.2	L772D	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	L772E	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	L772F	Neutral	0.14
NOTCH3	Q9UM47-1.2	L772G	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L772H	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	L772I	Neutral	0.008
NOTCH3	Q9UM47-1.2	L772K	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	L772M	Neutral	0.008
NOTCH3	Q9UM47-1.2	L772N	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	L772P	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	L772Q	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	L772R	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	L772S	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	L772T	Neutral	0.41
NOTCH3	Q9UM47-1.2	L772V	Neutral	0.034
NOTCH3	Q9UM47-1.2	L772W	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	L772Y	Neutral	0.421
NOTCH3	Q9UM47-1.2	S773A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S773C	Neutral	0.024
NOTCH3	Q9UM47-1.2	S773D	Neutral	0.005
NOTCH3	Q9UM47-1.2	S773E	Neutral	0.005
NOTCH3	Q9UM47-1.2	S773F	Neutral	0.084
NOTCH3	Q9UM47-1.2	S773G	Neutral	0.005
NOTCH3	Q9UM47-1.2	S773H	Neutral	0.021
NOTCH3	Q9UM47-1.2	S773I	Neutral	0.088
NOTCH3	Q9UM47-1.2	S773K	Neutral	0.004
NOTCH3	Q9UM47-1.2	S773L	Neutral	0.088
NOTCH3	Q9UM47-1.2	S773M	Neutral	0.021
NOTCH3	Q9UM47-1.2	S773N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S773P	Neutral	0.023
NOTCH3	Q9UM47-1.2	S773Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	S773R	Neutral	0.019
NOTCH3	Q9UM47-1.2	S773T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S773V	Neutral	0.093
NOTCH3	Q9UM47-1.2	S773W	Neutral	0.274
NOTCH3	Q9UM47-1.2	S773Y	Neutral	0.082
NOTCH3	Q9UM47-1.2	P774A	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	P774C	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	P774D	Pathogenic	0.649
NOTCH3	Q9UM47-1.2	P774E	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	P774F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	P774G	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	P774H	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	P774I	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	P774K	Pathogenic	0.609
NOTCH3	Q9UM47-1.2	P774L	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	P774M	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	P774N	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	P774Q	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	P774R	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	P774S	Pathogenic	0.633
NOTCH3	Q9UM47-1.2	P774T	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	P774V	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	P774W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	P774Y	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	C775A	Neutral	0.443
NOTCH3	Q9UM47-1.2	C775D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C775E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C775F	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	C775G	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C775H	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C775I	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	C775K	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C775L	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	C775M	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	C775N	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C775P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C775Q	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C775R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C775S	Pathogenic	0.788
NOTCH3	Q9UM47-1.2	C775T	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	C775V	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	C775W	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	C775Y	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	T776A	Neutral	0.004
NOTCH3	Q9UM47-1.2	T776C	Neutral	0.02
NOTCH3	Q9UM47-1.2	T776D	Neutral	0.02
NOTCH3	Q9UM47-1.2	T776E	Neutral	0.019
NOTCH3	Q9UM47-1.2	T776F	Neutral	0.074
NOTCH3	Q9UM47-1.2	T776G	Neutral	0.073
NOTCH3	Q9UM47-1.2	T776H	Neutral	0.078
NOTCH3	Q9UM47-1.2	T776I	Neutral	0.018
NOTCH3	Q9UM47-1.2	T776K	Neutral	0.017
NOTCH3	Q9UM47-1.2	T776L	Neutral	0.018
NOTCH3	Q9UM47-1.2	T776M	Neutral	0.018
NOTCH3	Q9UM47-1.2	T776N	Neutral	0.004
NOTCH3	Q9UM47-1.2	T776P	Neutral	0.02
NOTCH3	Q9UM47-1.2	T776Q	Neutral	0.019
NOTCH3	Q9UM47-1.2	T776R	Neutral	0.016
NOTCH3	Q9UM47-1.2	T776S	Neutral	0.001
NOTCH3	Q9UM47-1.2	T776V	Neutral	0.004
NOTCH3	Q9UM47-1.2	T776W	Neutral	0.067
NOTCH3	Q9UM47-1.2	T776Y	Neutral	0.072
NOTCH3	Q9UM47-1.2	P777A	Neutral	0.271
NOTCH3	Q9UM47-1.2	P777C	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	P777D	Neutral	0.29
NOTCH3	Q9UM47-1.2	P777E	Neutral	0.276
NOTCH3	Q9UM47-1.2	P777F	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	P777G	Pathogenic	0.612
NOTCH3	Q9UM47-1.2	P777H	Pathogenic	0.624
NOTCH3	Q9UM47-1.2	P777I	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	P777K	Neutral	0.257
NOTCH3	Q9UM47-1.2	P777L	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	P777M	Pathogenic	0.619
NOTCH3	Q9UM47-1.2	P777N	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	P777Q	Neutral	0.271
NOTCH3	Q9UM47-1.2	P777R	Pathogenic	0.599
NOTCH3	Q9UM47-1.2	P777S	Neutral	0.276
NOTCH3	Q9UM47-1.2	P777T	Neutral	0.287
NOTCH3	Q9UM47-1.2	P777V	Pathogenic	0.636
NOTCH3	Q9UM47-1.2	P777W	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	P777Y	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	N778A	Neutral	0.364
NOTCH3	Q9UM47-1.2	N778C	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	N778D	Neutral	0.007
NOTCH3	Q9UM47-1.2	N778E	Neutral	0.028
NOTCH3	Q9UM47-1.2	N778F	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	N778G	Neutral	0.025
NOTCH3	Q9UM47-1.2	N778H	Neutral	0.006
NOTCH3	Q9UM47-1.2	N778I	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	N778K	Neutral	0.026
NOTCH3	Q9UM47-1.2	N778L	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	N778M	Neutral	0.367
NOTCH3	Q9UM47-1.2	N778P	Neutral	0.386
NOTCH3	Q9UM47-1.2	N778Q	Neutral	0.028
NOTCH3	Q9UM47-1.2	N778R	Neutral	0.025
NOTCH3	Q9UM47-1.2	N778S	Neutral	0.006
NOTCH3	Q9UM47-1.2	N778T	Neutral	0.03
NOTCH3	Q9UM47-1.2	N778V	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	N778W	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	N778Y	Neutral	0.351
NOTCH3	Q9UM47-1.2	P779A	Neutral	0.443
NOTCH3	Q9UM47-1.2	P779C	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	P779D	Neutral	0.466
NOTCH3	Q9UM47-1.2	P779E	Neutral	0.449
NOTCH3	Q9UM47-1.2	P779F	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	P779G	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	P779H	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	P779I	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	P779K	Neutral	0.425
NOTCH3	Q9UM47-1.2	P779L	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	P779M	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	P779N	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	P779Q	Neutral	0.443
NOTCH3	Q9UM47-1.2	P779R	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	P779S	Neutral	0.449
NOTCH3	Q9UM47-1.2	P779T	Neutral	0.462
NOTCH3	Q9UM47-1.2	P779V	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	P779W	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	P779Y	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C780A	Neutral	0.448
NOTCH3	Q9UM47-1.2	C780D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C780E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C780F	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	C780G	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C780H	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C780I	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	C780K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C780L	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	C780M	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	C780N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C780P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C780Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C780R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C780S	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	C780T	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	C780V	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	C780W	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	C780Y	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	E781A	Neutral	0.145
NOTCH3	Q9UM47-1.2	E781C	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	E781D	Neutral	0.002
NOTCH3	Q9UM47-1.2	E781F	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	E781G	Neutral	0.418
NOTCH3	Q9UM47-1.2	E781H	Neutral	0.041
NOTCH3	Q9UM47-1.2	E781I	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	E781K	Neutral	0.009
NOTCH3	Q9UM47-1.2	E781L	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	E781M	Neutral	0.464
NOTCH3	Q9UM47-1.2	E781N	Neutral	0.04
NOTCH3	Q9UM47-1.2	E781P	Neutral	0.157
NOTCH3	Q9UM47-1.2	E781Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	E781R	Neutral	0.036
NOTCH3	Q9UM47-1.2	E781S	Neutral	0.037
NOTCH3	Q9UM47-1.2	E781T	Neutral	0.158
NOTCH3	Q9UM47-1.2	E781V	Neutral	0.474
NOTCH3	Q9UM47-1.2	E781W	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	E781Y	Neutral	0.447
NOTCH3	Q9UM47-1.2	H782A	Neutral	0.493
NOTCH3	Q9UM47-1.2	H782C	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	H782D	Neutral	0.191
NOTCH3	Q9UM47-1.2	H782E	Neutral	0.052
NOTCH3	Q9UM47-1.2	H782F	Neutral	0.198
NOTCH3	Q9UM47-1.2	H782G	Neutral	0.474
NOTCH3	Q9UM47-1.2	H782I	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	H782K	Neutral	0.197
NOTCH3	Q9UM47-1.2	H782L	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	H782M	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	H782N	Neutral	0.011
NOTCH3	Q9UM47-1.2	H782P	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	H782Q	Neutral	0.053
NOTCH3	Q9UM47-1.2	H782R	Neutral	0.049
NOTCH3	Q9UM47-1.2	H782S	Neutral	0.179
NOTCH3	Q9UM47-1.2	H782T	Pathogenic	0.518
NOTCH3	Q9UM47-1.2	H782V	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	H782W	Pathogenic	0.502
NOTCH3	Q9UM47-1.2	H782Y	Neutral	0.003
NOTCH3	Q9UM47-1.2	G783A	Neutral	0.022
NOTCH3	Q9UM47-1.2	G783C	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	G783D	Neutral	0.086
NOTCH3	Q9UM47-1.2	G783E	Neutral	0.285
NOTCH3	Q9UM47-1.2	G783F	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	G783H	Neutral	0.277
NOTCH3	Q9UM47-1.2	G783I	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	G783K	Neutral	0.265
NOTCH3	Q9UM47-1.2	G783L	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	G783M	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	G783N	Neutral	0.02
NOTCH3	Q9UM47-1.2	G783P	Neutral	0.3
NOTCH3	Q9UM47-1.2	G783Q	Neutral	0.28
NOTCH3	Q9UM47-1.2	G783R	Neutral	0.256
NOTCH3	Q9UM47-1.2	G783S	Neutral	0.021
NOTCH3	Q9UM47-1.2	G783T	Neutral	0.297
NOTCH3	Q9UM47-1.2	G783V	Pathogenic	0.649
NOTCH3	Q9UM47-1.2	G783W	Neutral	0.247
NOTCH3	Q9UM47-1.2	G783Y	Pathogenic	0.616
NOTCH3	Q9UM47-1.2	G784A	Neutral	0.073
NOTCH3	Q9UM47-1.2	G784C	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	G784D	Neutral	0.248
NOTCH3	Q9UM47-1.2	G784E	Pathogenic	0.583
NOTCH3	Q9UM47-1.2	G784F	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	G784H	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	G784I	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	G784K	Pathogenic	0.559
NOTCH3	Q9UM47-1.2	G784L	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	G784M	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	G784N	Neutral	0.066
NOTCH3	Q9UM47-1.2	G784P	Pathogenic	0.601
NOTCH3	Q9UM47-1.2	G784Q	Pathogenic	0.577
NOTCH3	Q9UM47-1.2	G784R	Pathogenic	0.547
NOTCH3	Q9UM47-1.2	G784S	Neutral	0.072
NOTCH3	Q9UM47-1.2	G784T	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	G784V	Pathogenic	0.867
NOTCH3	Q9UM47-1.2	G784W	Pathogenic	0.535
NOTCH3	Q9UM47-1.2	G784Y	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	R785A	Neutral	0.005
NOTCH3	Q9UM47-1.2	R785C	Neutral	0.099
NOTCH3	Q9UM47-1.2	R785D	Neutral	0.024
NOTCH3	Q9UM47-1.2	R785E	Neutral	0.001
NOTCH3	Q9UM47-1.2	R785F	Neutral	0.118
NOTCH3	Q9UM47-1.2	R785G	Neutral	0.02
NOTCH3	Q9UM47-1.2	R785H	Neutral	0.001
NOTCH3	Q9UM47-1.2	R785I	Neutral	0.113
NOTCH3	Q9UM47-1.2	R785K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R785L	Neutral	0.027
NOTCH3	Q9UM47-1.2	R785M	Neutral	0.006
NOTCH3	Q9UM47-1.2	R785N	Neutral	0.001
NOTCH3	Q9UM47-1.2	R785P	Neutral	0.024
NOTCH3	Q9UM47-1.2	R785Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	R785S	Neutral	0.005
NOTCH3	Q9UM47-1.2	R785T	Neutral	0.005
NOTCH3	Q9UM47-1.2	R785V	Neutral	0.106
NOTCH3	Q9UM47-1.2	R785W	Neutral	0.117
NOTCH3	Q9UM47-1.2	R785Y	Neutral	0.029
NOTCH3	Q9UM47-1.2	C786A	Neutral	0.467
NOTCH3	Q9UM47-1.2	C786D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C786E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C786F	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C786G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C786H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C786I	Pathogenic	0.788
NOTCH3	Q9UM47-1.2	C786K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C786L	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	C786M	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	C786N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C786P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C786Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C786R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C786S	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C786T	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C786V	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	C786W	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	C786Y	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	E787A	Neutral	0.013
NOTCH3	Q9UM47-1.2	E787C	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	E787D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E787F	Neutral	0.228
NOTCH3	Q9UM47-1.2	E787G	Neutral	0.053
NOTCH3	Q9UM47-1.2	E787H	Neutral	0.003
NOTCH3	Q9UM47-1.2	E787I	Neutral	0.236
NOTCH3	Q9UM47-1.2	E787K	Neutral	0.001
NOTCH3	Q9UM47-1.2	E787L	Neutral	0.236
NOTCH3	Q9UM47-1.2	E787M	Neutral	0.063
NOTCH3	Q9UM47-1.2	E787N	Neutral	0.003
NOTCH3	Q9UM47-1.2	E787P	Neutral	0.014
NOTCH3	Q9UM47-1.2	E787Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E787R	Neutral	0.003
NOTCH3	Q9UM47-1.2	E787S	Neutral	0.003
NOTCH3	Q9UM47-1.2	E787T	Neutral	0.014
NOTCH3	Q9UM47-1.2	E787V	Neutral	0.066
NOTCH3	Q9UM47-1.2	E787W	Neutral	0.211
NOTCH3	Q9UM47-1.2	E787Y	Neutral	0.059
NOTCH3	Q9UM47-1.2	S788A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S788C	Neutral	0.017
NOTCH3	Q9UM47-1.2	S788D	Neutral	0.004
NOTCH3	Q9UM47-1.2	S788E	Neutral	0.003
NOTCH3	Q9UM47-1.2	S788F	Neutral	0.062
NOTCH3	Q9UM47-1.2	S788G	Neutral	0.004
NOTCH3	Q9UM47-1.2	S788H	Neutral	0.015
NOTCH3	Q9UM47-1.2	S788I	Neutral	0.065
NOTCH3	Q9UM47-1.2	S788K	Neutral	0.003
NOTCH3	Q9UM47-1.2	S788L	Neutral	0.065
NOTCH3	Q9UM47-1.2	S788M	Neutral	0.015
NOTCH3	Q9UM47-1.2	S788N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S788P	Neutral	0.017
NOTCH3	Q9UM47-1.2	S788Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	S788R	Neutral	0.014
NOTCH3	Q9UM47-1.2	S788T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S788V	Neutral	0.069
NOTCH3	Q9UM47-1.2	S788W	Neutral	0.214
NOTCH3	Q9UM47-1.2	S788Y	Neutral	0.06
NOTCH3	Q9UM47-1.2	A789C	Neutral	0.021
NOTCH3	Q9UM47-1.2	A789D	Neutral	0.302
NOTCH3	Q9UM47-1.2	A789E	Neutral	0.081
NOTCH3	Q9UM47-1.2	A789F	Neutral	0.268
NOTCH3	Q9UM47-1.2	A789G	Neutral	0.021
NOTCH3	Q9UM47-1.2	A789H	Neutral	0.279
NOTCH3	Q9UM47-1.2	A789I	Neutral	0.077
NOTCH3	Q9UM47-1.2	A789K	Neutral	0.074
NOTCH3	Q9UM47-1.2	A789L	Neutral	0.077
NOTCH3	Q9UM47-1.2	A789M	Neutral	0.077
NOTCH3	Q9UM47-1.2	A789N	Neutral	0.297
NOTCH3	Q9UM47-1.2	A789P	Neutral	0.087
NOTCH3	Q9UM47-1.2	A789Q	Neutral	0.08
NOTCH3	Q9UM47-1.2	A789R	Neutral	0.071
NOTCH3	Q9UM47-1.2	A789S	Neutral	0.005
NOTCH3	Q9UM47-1.2	A789T	Neutral	0.02
NOTCH3	Q9UM47-1.2	A789V	Neutral	0.019
NOTCH3	Q9UM47-1.2	A789W	Pathogenic	0.6
NOTCH3	Q9UM47-1.2	A789Y	Neutral	0.262
NOTCH3	Q9UM47-1.2	P790A	Neutral	0.104
NOTCH3	Q9UM47-1.2	P790C	Pathogenic	0.721
NOTCH3	Q9UM47-1.2	P790D	Neutral	0.113
NOTCH3	Q9UM47-1.2	P790E	Neutral	0.106
NOTCH3	Q9UM47-1.2	P790F	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	P790G	Neutral	0.33
NOTCH3	Q9UM47-1.2	P790H	Neutral	0.342
NOTCH3	Q9UM47-1.2	P790I	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	P790K	Neutral	0.097
NOTCH3	Q9UM47-1.2	P790L	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	P790M	Neutral	0.337
NOTCH3	Q9UM47-1.2	P790N	Neutral	0.363
NOTCH3	Q9UM47-1.2	P790Q	Neutral	0.104
NOTCH3	Q9UM47-1.2	P790R	Neutral	0.318
NOTCH3	Q9UM47-1.2	P790S	Neutral	0.107
NOTCH3	Q9UM47-1.2	P790T	Neutral	0.112
NOTCH3	Q9UM47-1.2	P790V	Neutral	0.353
NOTCH3	Q9UM47-1.2	P790W	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	P790Y	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	G791A	Neutral	0.003
NOTCH3	Q9UM47-1.2	G791C	Neutral	0.204
NOTCH3	Q9UM47-1.2	G791D	Neutral	0.012
NOTCH3	Q9UM47-1.2	G791E	Neutral	0.049
NOTCH3	Q9UM47-1.2	G791F	Neutral	0.176
NOTCH3	Q9UM47-1.2	G791H	Neutral	0.047
NOTCH3	Q9UM47-1.2	G791I	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	G791K	Neutral	0.045
NOTCH3	Q9UM47-1.2	G791L	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	G791M	Neutral	0.182
NOTCH3	Q9UM47-1.2	G791N	Neutral	0.003
NOTCH3	Q9UM47-1.2	G791P	Neutral	0.053
NOTCH3	Q9UM47-1.2	G791Q	Neutral	0.048
NOTCH3	Q9UM47-1.2	G791R	Neutral	0.043
NOTCH3	Q9UM47-1.2	G791S	Neutral	0.003
NOTCH3	Q9UM47-1.2	G791T	Neutral	0.052
NOTCH3	Q9UM47-1.2	G791V	Neutral	0.193
NOTCH3	Q9UM47-1.2	G791W	Neutral	0.041
NOTCH3	Q9UM47-1.2	G791Y	Neutral	0.172
NOTCH3	Q9UM47-1.2	Q792A	Neutral	0.051
NOTCH3	Q9UM47-1.2	Q792C	Pathogenic	0.545
NOTCH3	Q9UM47-1.2	Q792D	Neutral	0.013
NOTCH3	Q9UM47-1.2	Q792E	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q792F	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	Q792G	Neutral	0.184
NOTCH3	Q9UM47-1.2	Q792H	Neutral	0.014
NOTCH3	Q9UM47-1.2	Q792I	Pathogenic	0.564
NOTCH3	Q9UM47-1.2	Q792K	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q792L	Neutral	0.221
NOTCH3	Q9UM47-1.2	Q792M	Neutral	0.013
NOTCH3	Q9UM47-1.2	Q792N	Neutral	0.013
NOTCH3	Q9UM47-1.2	Q792P	Neutral	0.055
NOTCH3	Q9UM47-1.2	Q792R	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q792S	Neutral	0.012
NOTCH3	Q9UM47-1.2	Q792T	Neutral	0.056
NOTCH3	Q9UM47-1.2	Q792V	Neutral	0.221
NOTCH3	Q9UM47-1.2	Q792W	Neutral	0.197
NOTCH3	Q9UM47-1.2	Q792Y	Neutral	0.055
NOTCH3	Q9UM47-1.2	L793A	Neutral	0.008
NOTCH3	Q9UM47-1.2	L793C	Neutral	0.009
NOTCH3	Q9UM47-1.2	L793D	Neutral	0.457
NOTCH3	Q9UM47-1.2	L793E	Neutral	0.165
NOTCH3	Q9UM47-1.2	L793F	Neutral	0.002
NOTCH3	Q9UM47-1.2	L793G	Neutral	0.414
NOTCH3	Q9UM47-1.2	L793H	Neutral	0.169
NOTCH3	Q9UM47-1.2	L793I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L793K	Neutral	0.042
NOTCH3	Q9UM47-1.2	L793M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L793N	Neutral	0.158
NOTCH3	Q9UM47-1.2	L793P	Neutral	0.154
NOTCH3	Q9UM47-1.2	L793Q	Neutral	0.042
NOTCH3	Q9UM47-1.2	L793R	Neutral	0.04
NOTCH3	Q9UM47-1.2	L793S	Neutral	0.036
NOTCH3	Q9UM47-1.2	L793T	Neutral	0.009
NOTCH3	Q9UM47-1.2	L793V	Neutral	0.0
NOTCH3	Q9UM47-1.2	L793W	Neutral	0.038
NOTCH3	Q9UM47-1.2	L793Y	Neutral	0.009
NOTCH3	Q9UM47-1.2	P794A	Neutral	0.002
NOTCH3	Q9UM47-1.2	P794C	Neutral	0.048
NOTCH3	Q9UM47-1.2	P794D	Neutral	0.002
NOTCH3	Q9UM47-1.2	P794E	Neutral	0.002
NOTCH3	Q9UM47-1.2	P794F	Neutral	0.164
NOTCH3	Q9UM47-1.2	P794G	Neutral	0.009
NOTCH3	Q9UM47-1.2	P794H	Neutral	0.01
NOTCH3	Q9UM47-1.2	P794I	Neutral	0.043
NOTCH3	Q9UM47-1.2	P794K	Neutral	0.002
NOTCH3	Q9UM47-1.2	P794L	Neutral	0.043
NOTCH3	Q9UM47-1.2	P794M	Neutral	0.01
NOTCH3	Q9UM47-1.2	P794N	Neutral	0.011
NOTCH3	Q9UM47-1.2	P794Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	P794R	Neutral	0.009
NOTCH3	Q9UM47-1.2	P794S	Neutral	0.002
NOTCH3	Q9UM47-1.2	P794T	Neutral	0.002
NOTCH3	Q9UM47-1.2	P794V	Neutral	0.01
NOTCH3	Q9UM47-1.2	P794W	Neutral	0.151
NOTCH3	Q9UM47-1.2	P794Y	Neutral	0.04
NOTCH3	Q9UM47-1.2	V795A	Neutral	0.007
NOTCH3	Q9UM47-1.2	V795C	Neutral	0.031
NOTCH3	Q9UM47-1.2	V795D	Neutral	0.41
NOTCH3	Q9UM47-1.2	V795E	Neutral	0.137
NOTCH3	Q9UM47-1.2	V795F	Neutral	0.03
NOTCH3	Q9UM47-1.2	V795G	Neutral	0.369
NOTCH3	Q9UM47-1.2	V795H	Neutral	0.409
NOTCH3	Q9UM47-1.2	V795I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V795K	Neutral	0.126
NOTCH3	Q9UM47-1.2	V795L	Neutral	0.002
NOTCH3	Q9UM47-1.2	V795M	Neutral	0.002
NOTCH3	Q9UM47-1.2	V795N	Neutral	0.414
NOTCH3	Q9UM47-1.2	V795P	Neutral	0.13
NOTCH3	Q9UM47-1.2	V795Q	Neutral	0.134
NOTCH3	Q9UM47-1.2	V795R	Neutral	0.383
NOTCH3	Q9UM47-1.2	V795S	Neutral	0.124
NOTCH3	Q9UM47-1.2	V795T	Neutral	0.007
NOTCH3	Q9UM47-1.2	V795W	Neutral	0.368
NOTCH3	Q9UM47-1.2	V795Y	Neutral	0.029
NOTCH3	Q9UM47-1.2	C796A	Neutral	0.486
NOTCH3	Q9UM47-1.2	C796D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C796E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C796F	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	C796G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C796H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C796I	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	C796K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C796L	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	C796M	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	C796N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C796P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C796Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C796R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C796S	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C796T	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C796V	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C796W	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	C796Y	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	S797A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S797C	Neutral	0.015
NOTCH3	Q9UM47-1.2	S797D	Neutral	0.003
NOTCH3	Q9UM47-1.2	S797E	Neutral	0.003
NOTCH3	Q9UM47-1.2	S797F	Neutral	0.053
NOTCH3	Q9UM47-1.2	S797G	Neutral	0.003
NOTCH3	Q9UM47-1.2	S797H	Neutral	0.013
NOTCH3	Q9UM47-1.2	S797I	Neutral	0.055
NOTCH3	Q9UM47-1.2	S797K	Neutral	0.003
NOTCH3	Q9UM47-1.2	S797L	Neutral	0.055
NOTCH3	Q9UM47-1.2	S797M	Neutral	0.013
NOTCH3	Q9UM47-1.2	S797N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S797P	Neutral	0.014
NOTCH3	Q9UM47-1.2	S797Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	S797R	Neutral	0.011
NOTCH3	Q9UM47-1.2	S797T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S797V	Neutral	0.059
NOTCH3	Q9UM47-1.2	S797W	Neutral	0.187
NOTCH3	Q9UM47-1.2	S797Y	Neutral	0.051
NOTCH3	Q9UM47-1.2	C798A	Neutral	0.486
NOTCH3	Q9UM47-1.2	C798D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C798E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C798F	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	C798G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C798H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C798I	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	C798K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C798L	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	C798M	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	C798N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C798P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C798Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C798R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C798S	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C798T	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C798V	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C798W	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	C798Y	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	P799A	Neutral	0.137
NOTCH3	Q9UM47-1.2	P799C	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	P799D	Neutral	0.149
NOTCH3	Q9UM47-1.2	P799E	Neutral	0.14
NOTCH3	Q9UM47-1.2	P799F	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	P799G	Neutral	0.403
NOTCH3	Q9UM47-1.2	P799H	Neutral	0.415
NOTCH3	Q9UM47-1.2	P799I	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	P799K	Neutral	0.129
NOTCH3	Q9UM47-1.2	P799L	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	P799M	Neutral	0.41
NOTCH3	Q9UM47-1.2	P799N	Neutral	0.438
NOTCH3	Q9UM47-1.2	P799Q	Neutral	0.137
NOTCH3	Q9UM47-1.2	P799R	Neutral	0.39
NOTCH3	Q9UM47-1.2	P799S	Neutral	0.14
NOTCH3	Q9UM47-1.2	P799T	Neutral	0.146
NOTCH3	Q9UM47-1.2	P799V	Neutral	0.427
NOTCH3	Q9UM47-1.2	P799W	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	P799Y	Pathogenic	0.747
NOTCH3	Q9UM47-1.2	Q800A	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q800C	Neutral	0.035
NOTCH3	Q9UM47-1.2	Q800D	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q800E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q800F	Neutral	0.036
NOTCH3	Q9UM47-1.2	Q800G	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q800H	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q800I	Neutral	0.037
NOTCH3	Q9UM47-1.2	Q800K	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q800L	Neutral	0.008
NOTCH3	Q9UM47-1.2	Q800M	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q800N	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q800P	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q800R	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q800S	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q800T	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q800V	Neutral	0.008
NOTCH3	Q9UM47-1.2	Q800W	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q800Y	Neutral	0.002
NOTCH3	Q9UM47-1.2	G801A	Neutral	0.221
NOTCH3	Q9UM47-1.2	G801C	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	G801D	Pathogenic	0.542
NOTCH3	Q9UM47-1.2	G801E	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	G801F	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G801H	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	G801I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G801K	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	G801L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G801M	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G801N	Neutral	0.203
NOTCH3	Q9UM47-1.2	G801P	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	G801Q	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	G801R	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	G801S	Neutral	0.217
NOTCH3	Q9UM47-1.2	G801T	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	G801V	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G801W	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	G801Y	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	W802A	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W802C	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	W802D	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W802E	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W802F	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	W802G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	W802H	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W802I	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W802K	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W802L	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W802M	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	W802N	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W802P	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W802Q	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W802R	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W802S	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W802T	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	W802V	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W802Y	Neutral	0.44
NOTCH3	Q9UM47-1.2	Q803A	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	Q803C	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	Q803D	Neutral	0.24
NOTCH3	Q9UM47-1.2	Q803E	Neutral	0.016
NOTCH3	Q9UM47-1.2	Q803F	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	Q803G	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	Q803H	Neutral	0.253
NOTCH3	Q9UM47-1.2	Q803I	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	Q803K	Neutral	0.065
NOTCH3	Q9UM47-1.2	Q803L	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	Q803M	Neutral	0.25
NOTCH3	Q9UM47-1.2	Q803N	Neutral	0.243
NOTCH3	Q9UM47-1.2	Q803P	Pathogenic	0.589
NOTCH3	Q9UM47-1.2	Q803R	Neutral	0.062
NOTCH3	Q9UM47-1.2	Q803S	Neutral	0.227
NOTCH3	Q9UM47-1.2	Q803T	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	Q803V	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	Q803W	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	Q803Y	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	G804A	Neutral	0.236
NOTCH3	Q9UM47-1.2	G804C	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	G804D	Pathogenic	0.562
NOTCH3	Q9UM47-1.2	G804E	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	G804F	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G804H	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	G804I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G804K	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	G804L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G804M	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G804N	Neutral	0.217
NOTCH3	Q9UM47-1.2	G804P	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	G804Q	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	G804R	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	G804S	Neutral	0.231
NOTCH3	Q9UM47-1.2	G804T	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	G804V	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	G804W	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	G804Y	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	P805A	Neutral	0.012
NOTCH3	Q9UM47-1.2	P805C	Neutral	0.218
NOTCH3	Q9UM47-1.2	P805D	Neutral	0.014
NOTCH3	Q9UM47-1.2	P805E	Neutral	0.013
NOTCH3	Q9UM47-1.2	P805F	Pathogenic	0.522
NOTCH3	Q9UM47-1.2	P805G	Neutral	0.05
NOTCH3	Q9UM47-1.2	P805H	Neutral	0.053
NOTCH3	Q9UM47-1.2	P805I	Neutral	0.2
NOTCH3	Q9UM47-1.2	P805K	Neutral	0.011
NOTCH3	Q9UM47-1.2	P805L	Neutral	0.2
NOTCH3	Q9UM47-1.2	P805M	Neutral	0.052
NOTCH3	Q9UM47-1.2	P805N	Neutral	0.058
NOTCH3	Q9UM47-1.2	P805Q	Neutral	0.012
NOTCH3	Q9UM47-1.2	P805R	Neutral	0.048
NOTCH3	Q9UM47-1.2	P805S	Neutral	0.013
NOTCH3	Q9UM47-1.2	P805T	Neutral	0.013
NOTCH3	Q9UM47-1.2	P805V	Neutral	0.056
NOTCH3	Q9UM47-1.2	P805W	Neutral	0.496
NOTCH3	Q9UM47-1.2	P805Y	Neutral	0.189
NOTCH3	Q9UM47-1.2	R806A	Neutral	0.212
NOTCH3	Q9UM47-1.2	R806C	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	R806D	Pathogenic	0.571
NOTCH3	Q9UM47-1.2	R806E	Neutral	0.064
NOTCH3	Q9UM47-1.2	R806F	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	R806G	Pathogenic	0.531
NOTCH3	Q9UM47-1.2	R806H	Neutral	0.067
NOTCH3	Q9UM47-1.2	R806I	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	R806K	Neutral	0.004
NOTCH3	Q9UM47-1.2	R806L	Pathogenic	0.606
NOTCH3	Q9UM47-1.2	R806M	Neutral	0.252
NOTCH3	Q9UM47-1.2	R806N	Neutral	0.061
NOTCH3	Q9UM47-1.2	R806P	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	R806Q	Neutral	0.015
NOTCH3	Q9UM47-1.2	R806S	Neutral	0.215
NOTCH3	Q9UM47-1.2	R806T	Neutral	0.229
NOTCH3	Q9UM47-1.2	R806V	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	R806W	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	R806Y	Pathogenic	0.62
NOTCH3	Q9UM47-1.2	C807A	Pathogenic	0.51
NOTCH3	Q9UM47-1.2	C807D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C807E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C807F	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	C807G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C807H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C807I	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C807K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C807L	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C807M	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C807N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C807P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C807Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C807R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C807S	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C807T	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	C807V	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C807W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C807Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	Q808A	Neutral	0.026
NOTCH3	Q9UM47-1.2	Q808C	Neutral	0.371
NOTCH3	Q9UM47-1.2	Q808D	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q808E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q808F	Neutral	0.379
NOTCH3	Q9UM47-1.2	Q808G	Neutral	0.1
NOTCH3	Q9UM47-1.2	Q808H	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q808I	Neutral	0.389
NOTCH3	Q9UM47-1.2	Q808K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q808L	Neutral	0.122
NOTCH3	Q9UM47-1.2	Q808M	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q808N	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q808P	Neutral	0.028
NOTCH3	Q9UM47-1.2	Q808R	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q808S	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q808T	Neutral	0.028
NOTCH3	Q9UM47-1.2	Q808V	Neutral	0.122
NOTCH3	Q9UM47-1.2	Q808W	Neutral	0.108
NOTCH3	Q9UM47-1.2	Q808Y	Neutral	0.028
NOTCH3	Q9UM47-1.2	Q809A	Neutral	0.027
NOTCH3	Q9UM47-1.2	Q809C	Neutral	0.387
NOTCH3	Q9UM47-1.2	Q809D	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q809E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q809F	Neutral	0.395
NOTCH3	Q9UM47-1.2	Q809G	Neutral	0.106
NOTCH3	Q9UM47-1.2	Q809H	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q809I	Neutral	0.405
NOTCH3	Q9UM47-1.2	Q809K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q809L	Neutral	0.13
NOTCH3	Q9UM47-1.2	Q809M	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q809N	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q809P	Neutral	0.03
NOTCH3	Q9UM47-1.2	Q809R	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q809S	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q809T	Neutral	0.03
NOTCH3	Q9UM47-1.2	Q809V	Neutral	0.13
NOTCH3	Q9UM47-1.2	Q809W	Neutral	0.114
NOTCH3	Q9UM47-1.2	Q809Y	Neutral	0.03
NOTCH3	Q9UM47-1.2	D810A	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	D810C	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	D810E	Neutral	0.035
NOTCH3	Q9UM47-1.2	D810F	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D810G	Pathogenic	0.755
NOTCH3	Q9UM47-1.2	D810H	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	D810I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D810K	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	D810L	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	D810M	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D810N	Neutral	0.146
NOTCH3	Q9UM47-1.2	D810P	Pathogenic	0.785
NOTCH3	Q9UM47-1.2	D810Q	Neutral	0.422
NOTCH3	Q9UM47-1.2	D810R	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	D810S	Neutral	0.427
NOTCH3	Q9UM47-1.2	D810T	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	D810V	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D810W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D810Y	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	V811A	Neutral	0.06
NOTCH3	Q9UM47-1.2	V811C	Neutral	0.238
NOTCH3	Q9UM47-1.2	V811D	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	V811E	Pathogenic	0.604
NOTCH3	Q9UM47-1.2	V811F	Neutral	0.231
NOTCH3	Q9UM47-1.2	V811G	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	V811H	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	V811I	Neutral	0.001
NOTCH3	Q9UM47-1.2	V811K	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	V811L	Neutral	0.015
NOTCH3	Q9UM47-1.2	V811M	Neutral	0.015
NOTCH3	Q9UM47-1.2	V811N	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	V811P	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	V811Q	Pathogenic	0.598
NOTCH3	Q9UM47-1.2	V811R	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	V811S	Pathogenic	0.576
NOTCH3	Q9UM47-1.2	V811T	Neutral	0.066
NOTCH3	Q9UM47-1.2	V811W	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	V811Y	Neutral	0.226
NOTCH3	Q9UM47-1.2	D812A	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	D812C	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	D812E	Neutral	0.004
NOTCH3	Q9UM47-1.2	D812F	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	D812G	Neutral	0.258
NOTCH3	Q9UM47-1.2	D812H	Neutral	0.27
NOTCH3	Q9UM47-1.2	D812I	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	D812K	Neutral	0.256
NOTCH3	Q9UM47-1.2	D812L	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	D812M	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	D812N	Neutral	0.019
NOTCH3	Q9UM47-1.2	D812P	Neutral	0.291
NOTCH3	Q9UM47-1.2	D812Q	Neutral	0.076
NOTCH3	Q9UM47-1.2	D812R	Pathogenic	0.598
NOTCH3	Q9UM47-1.2	D812S	Neutral	0.077
NOTCH3	Q9UM47-1.2	D812T	Neutral	0.289
NOTCH3	Q9UM47-1.2	D812V	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	D812W	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	D812Y	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	E813A	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	E813C	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	E813D	Neutral	0.048
NOTCH3	Q9UM47-1.2	E813F	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	E813G	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	E813H	Pathogenic	0.519
NOTCH3	Q9UM47-1.2	E813I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	E813K	Neutral	0.181
NOTCH3	Q9UM47-1.2	E813L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	E813M	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	E813N	Pathogenic	0.514
NOTCH3	Q9UM47-1.2	E813P	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	E813Q	Neutral	0.05
NOTCH3	Q9UM47-1.2	E813R	Neutral	0.49
NOTCH3	Q9UM47-1.2	E813S	Neutral	0.493
NOTCH3	Q9UM47-1.2	E813T	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	E813V	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	E813W	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E813Y	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	C814A	Pathogenic	0.51
NOTCH3	Q9UM47-1.2	C814D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C814E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C814F	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	C814G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C814H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C814I	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C814K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C814L	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C814M	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C814N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C814P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C814Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C814R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C814S	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C814T	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	C814V	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C814W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C814Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	A815C	Neutral	0.005
NOTCH3	Q9UM47-1.2	A815D	Neutral	0.1
NOTCH3	Q9UM47-1.2	A815E	Neutral	0.022
NOTCH3	Q9UM47-1.2	A815F	Neutral	0.086
NOTCH3	Q9UM47-1.2	A815G	Neutral	0.005
NOTCH3	Q9UM47-1.2	A815H	Neutral	0.091
NOTCH3	Q9UM47-1.2	A815I	Neutral	0.021
NOTCH3	Q9UM47-1.2	A815K	Neutral	0.02
NOTCH3	Q9UM47-1.2	A815L	Neutral	0.021
NOTCH3	Q9UM47-1.2	A815M	Neutral	0.021
NOTCH3	Q9UM47-1.2	A815N	Neutral	0.098
NOTCH3	Q9UM47-1.2	A815P	Neutral	0.024
NOTCH3	Q9UM47-1.2	A815Q	Neutral	0.022
NOTCH3	Q9UM47-1.2	A815R	Neutral	0.019
NOTCH3	Q9UM47-1.2	A815S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A815T	Neutral	0.005
NOTCH3	Q9UM47-1.2	A815V	Neutral	0.005
NOTCH3	Q9UM47-1.2	A815W	Neutral	0.279
NOTCH3	Q9UM47-1.2	A815Y	Neutral	0.084
NOTCH3	Q9UM47-1.2	G816A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G816C	Neutral	0.142
NOTCH3	Q9UM47-1.2	G816D	Neutral	0.008
NOTCH3	Q9UM47-1.2	G816E	Neutral	0.032
NOTCH3	Q9UM47-1.2	G816F	Neutral	0.121
NOTCH3	Q9UM47-1.2	G816H	Neutral	0.031
NOTCH3	Q9UM47-1.2	G816I	Neutral	0.396
NOTCH3	Q9UM47-1.2	G816K	Neutral	0.029
NOTCH3	Q9UM47-1.2	G816L	Neutral	0.395
NOTCH3	Q9UM47-1.2	G816M	Neutral	0.125
NOTCH3	Q9UM47-1.2	G816N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G816P	Neutral	0.034
NOTCH3	Q9UM47-1.2	G816Q	Neutral	0.031
NOTCH3	Q9UM47-1.2	G816R	Neutral	0.028
NOTCH3	Q9UM47-1.2	G816S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G816T	Neutral	0.034
NOTCH3	Q9UM47-1.2	G816V	Neutral	0.133
NOTCH3	Q9UM47-1.2	G816W	Neutral	0.027
NOTCH3	Q9UM47-1.2	G816Y	Neutral	0.118
NOTCH3	Q9UM47-1.2	P817A	Neutral	0.009
NOTCH3	Q9UM47-1.2	P817C	Neutral	0.162
NOTCH3	Q9UM47-1.2	P817D	Neutral	0.009
NOTCH3	Q9UM47-1.2	P817E	Neutral	0.009
NOTCH3	Q9UM47-1.2	P817F	Neutral	0.431
NOTCH3	Q9UM47-1.2	P817G	Neutral	0.035
NOTCH3	Q9UM47-1.2	P817H	Neutral	0.037
NOTCH3	Q9UM47-1.2	P817I	Neutral	0.148
NOTCH3	Q9UM47-1.2	P817K	Neutral	0.008
NOTCH3	Q9UM47-1.2	P817L	Neutral	0.148
NOTCH3	Q9UM47-1.2	P817M	Neutral	0.037
NOTCH3	Q9UM47-1.2	P817N	Neutral	0.041
NOTCH3	Q9UM47-1.2	P817Q	Neutral	0.009
NOTCH3	Q9UM47-1.2	P817R	Neutral	0.034
NOTCH3	Q9UM47-1.2	P817S	Neutral	0.009
NOTCH3	Q9UM47-1.2	P817T	Neutral	0.009
NOTCH3	Q9UM47-1.2	P817V	Neutral	0.039
NOTCH3	Q9UM47-1.2	P817W	Neutral	0.405
NOTCH3	Q9UM47-1.2	P817Y	Neutral	0.139
NOTCH3	Q9UM47-1.2	A818C	Neutral	0.001
NOTCH3	Q9UM47-1.2	A818D	Neutral	0.011
NOTCH3	Q9UM47-1.2	A818E	Neutral	0.002
NOTCH3	Q9UM47-1.2	A818F	Neutral	0.009
NOTCH3	Q9UM47-1.2	A818G	Neutral	0.001
NOTCH3	Q9UM47-1.2	A818H	Neutral	0.01
NOTCH3	Q9UM47-1.2	A818I	Neutral	0.002
NOTCH3	Q9UM47-1.2	A818K	Neutral	0.002
NOTCH3	Q9UM47-1.2	A818L	Neutral	0.002
NOTCH3	Q9UM47-1.2	A818M	Neutral	0.002
NOTCH3	Q9UM47-1.2	A818N	Neutral	0.011
NOTCH3	Q9UM47-1.2	A818P	Neutral	0.002
NOTCH3	Q9UM47-1.2	A818Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	A818R	Neutral	0.002
NOTCH3	Q9UM47-1.2	A818S	Neutral	0.0
NOTCH3	Q9UM47-1.2	A818T	Neutral	0.001
NOTCH3	Q9UM47-1.2	A818V	Neutral	0.0
NOTCH3	Q9UM47-1.2	A818W	Neutral	0.037
NOTCH3	Q9UM47-1.2	A818Y	Neutral	0.009
NOTCH3	Q9UM47-1.2	P819A	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	P819C	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	P819D	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	P819E	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	P819F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P819G	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	P819H	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	P819I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P819K	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	P819L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P819M	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	P819N	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	P819Q	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	P819R	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	P819S	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	P819T	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	P819V	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	P819W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P819Y	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	C820A	Pathogenic	0.51
NOTCH3	Q9UM47-1.2	C820D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C820E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C820F	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	C820G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C820H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C820I	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C820K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C820L	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C820M	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C820N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C820P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C820Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C820R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C820S	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C820T	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	C820V	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C820W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C820Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	G821A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G821C	Neutral	0.138
NOTCH3	Q9UM47-1.2	G821D	Neutral	0.008
NOTCH3	Q9UM47-1.2	G821E	Neutral	0.031
NOTCH3	Q9UM47-1.2	G821F	Neutral	0.118
NOTCH3	Q9UM47-1.2	G821H	Neutral	0.03
NOTCH3	Q9UM47-1.2	G821I	Neutral	0.388
NOTCH3	Q9UM47-1.2	G821K	Neutral	0.028
NOTCH3	Q9UM47-1.2	G821L	Neutral	0.388
NOTCH3	Q9UM47-1.2	G821M	Neutral	0.122
NOTCH3	Q9UM47-1.2	G821N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G821P	Neutral	0.033
NOTCH3	Q9UM47-1.2	G821Q	Neutral	0.03
NOTCH3	Q9UM47-1.2	G821R	Neutral	0.027
NOTCH3	Q9UM47-1.2	G821S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G821T	Neutral	0.033
NOTCH3	Q9UM47-1.2	G821V	Neutral	0.13
NOTCH3	Q9UM47-1.2	G821W	Neutral	0.026
NOTCH3	Q9UM47-1.2	G821Y	Neutral	0.115
NOTCH3	Q9UM47-1.2	P822A	Neutral	0.017
NOTCH3	Q9UM47-1.2	P822C	Neutral	0.283
NOTCH3	Q9UM47-1.2	P822D	Neutral	0.019
NOTCH3	Q9UM47-1.2	P822E	Neutral	0.018
NOTCH3	Q9UM47-1.2	P822F	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	P822G	Neutral	0.07
NOTCH3	Q9UM47-1.2	P822H	Neutral	0.073
NOTCH3	Q9UM47-1.2	P822I	Neutral	0.261
NOTCH3	Q9UM47-1.2	P822K	Neutral	0.016
NOTCH3	Q9UM47-1.2	P822L	Neutral	0.261
NOTCH3	Q9UM47-1.2	P822M	Neutral	0.072
NOTCH3	Q9UM47-1.2	P822N	Neutral	0.08
NOTCH3	Q9UM47-1.2	P822Q	Neutral	0.017
NOTCH3	Q9UM47-1.2	P822R	Neutral	0.066
NOTCH3	Q9UM47-1.2	P822S	Neutral	0.018
NOTCH3	Q9UM47-1.2	P822T	Neutral	0.019
NOTCH3	Q9UM47-1.2	P822V	Neutral	0.077
NOTCH3	Q9UM47-1.2	P822W	Pathogenic	0.582
NOTCH3	Q9UM47-1.2	P822Y	Neutral	0.247
NOTCH3	Q9UM47-1.2	H823A	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	H823C	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	H823D	Neutral	0.357
NOTCH3	Q9UM47-1.2	H823E	Neutral	0.115
NOTCH3	Q9UM47-1.2	H823F	Neutral	0.367
NOTCH3	Q9UM47-1.2	H823G	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	H823I	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	H823K	Neutral	0.366
NOTCH3	Q9UM47-1.2	H823L	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	H823M	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	H823N	Neutral	0.027
NOTCH3	Q9UM47-1.2	H823P	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	H823Q	Neutral	0.117
NOTCH3	Q9UM47-1.2	H823R	Neutral	0.108
NOTCH3	Q9UM47-1.2	H823S	Neutral	0.34
NOTCH3	Q9UM47-1.2	H823T	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	H823V	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	H823W	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	H823Y	Neutral	0.006
NOTCH3	Q9UM47-1.2	G824A	Neutral	0.039
NOTCH3	Q9UM47-1.2	G824C	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	G824D	Neutral	0.146
NOTCH3	Q9UM47-1.2	G824E	Neutral	0.42
NOTCH3	Q9UM47-1.2	G824F	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	G824H	Neutral	0.411
NOTCH3	Q9UM47-1.2	G824I	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	G824K	Neutral	0.397
NOTCH3	Q9UM47-1.2	G824L	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	G824M	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	G824N	Neutral	0.035
NOTCH3	Q9UM47-1.2	G824P	Neutral	0.439
NOTCH3	Q9UM47-1.2	G824Q	Neutral	0.415
NOTCH3	Q9UM47-1.2	G824R	Neutral	0.385
NOTCH3	Q9UM47-1.2	G824S	Neutral	0.038
NOTCH3	Q9UM47-1.2	G824T	Neutral	0.435
NOTCH3	Q9UM47-1.2	G824V	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	G824W	Neutral	0.374
NOTCH3	Q9UM47-1.2	G824Y	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	I825A	Neutral	0.014
NOTCH3	Q9UM47-1.2	I825C	Neutral	0.015
NOTCH3	Q9UM47-1.2	I825D	Neutral	0.24
NOTCH3	Q9UM47-1.2	I825E	Neutral	0.253
NOTCH3	Q9UM47-1.2	I825F	Neutral	0.004
NOTCH3	Q9UM47-1.2	I825G	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	I825H	Neutral	0.258
NOTCH3	Q9UM47-1.2	I825K	Neutral	0.256
NOTCH3	Q9UM47-1.2	I825L	Neutral	0.0
NOTCH3	Q9UM47-1.2	I825M	Neutral	0.001
NOTCH3	Q9UM47-1.2	I825N	Neutral	0.244
NOTCH3	Q9UM47-1.2	I825P	Neutral	0.237
NOTCH3	Q9UM47-1.2	I825Q	Neutral	0.256
NOTCH3	Q9UM47-1.2	I825R	Neutral	0.247
NOTCH3	Q9UM47-1.2	I825S	Neutral	0.061
NOTCH3	Q9UM47-1.2	I825T	Neutral	0.015
NOTCH3	Q9UM47-1.2	I825V	Neutral	0.0
NOTCH3	Q9UM47-1.2	I825W	Neutral	0.233
NOTCH3	Q9UM47-1.2	I825Y	Neutral	0.016
NOTCH3	Q9UM47-1.2	C826A	Pathogenic	0.51
NOTCH3	Q9UM47-1.2	C826D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C826E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C826F	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	C826G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C826H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C826I	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C826K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C826L	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C826M	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C826N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C826P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C826Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C826R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C826S	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C826T	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	C826V	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C826W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C826Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	T827A	Neutral	0.006
NOTCH3	Q9UM47-1.2	T827C	Neutral	0.031
NOTCH3	Q9UM47-1.2	T827D	Neutral	0.032
NOTCH3	Q9UM47-1.2	T827E	Neutral	0.03
NOTCH3	Q9UM47-1.2	T827F	Neutral	0.113
NOTCH3	Q9UM47-1.2	T827G	Neutral	0.111
NOTCH3	Q9UM47-1.2	T827H	Neutral	0.119
NOTCH3	Q9UM47-1.2	T827I	Neutral	0.028
NOTCH3	Q9UM47-1.2	T827K	Neutral	0.027
NOTCH3	Q9UM47-1.2	T827L	Neutral	0.028
NOTCH3	Q9UM47-1.2	T827M	Neutral	0.028
NOTCH3	Q9UM47-1.2	T827N	Neutral	0.007
NOTCH3	Q9UM47-1.2	T827P	Neutral	0.031
NOTCH3	Q9UM47-1.2	T827Q	Neutral	0.029
NOTCH3	Q9UM47-1.2	T827R	Neutral	0.026
NOTCH3	Q9UM47-1.2	T827S	Neutral	0.001
NOTCH3	Q9UM47-1.2	T827V	Neutral	0.007
NOTCH3	Q9UM47-1.2	T827W	Neutral	0.103
NOTCH3	Q9UM47-1.2	T827Y	Neutral	0.11
NOTCH3	Q9UM47-1.2	N828A	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	N828C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N828D	Neutral	0.14
NOTCH3	Q9UM47-1.2	N828E	Neutral	0.418
NOTCH3	Q9UM47-1.2	N828F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N828G	Neutral	0.386
NOTCH3	Q9UM47-1.2	N828H	Neutral	0.133
NOTCH3	Q9UM47-1.2	N828I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N828K	Neutral	0.394
NOTCH3	Q9UM47-1.2	N828L	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N828M	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	N828P	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	N828Q	Neutral	0.414
NOTCH3	Q9UM47-1.2	N828R	Neutral	0.382
NOTCH3	Q9UM47-1.2	N828S	Neutral	0.132
NOTCH3	Q9UM47-1.2	N828T	Neutral	0.429
NOTCH3	Q9UM47-1.2	N828V	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N828W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N828Y	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	L829A	Neutral	0.027
NOTCH3	Q9UM47-1.2	L829C	Neutral	0.028
NOTCH3	Q9UM47-1.2	L829D	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	L829E	Neutral	0.401
NOTCH3	Q9UM47-1.2	L829F	Neutral	0.007
NOTCH3	Q9UM47-1.2	L829G	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	L829H	Neutral	0.408
NOTCH3	Q9UM47-1.2	L829I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L829K	Neutral	0.13
NOTCH3	Q9UM47-1.2	L829M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L829N	Neutral	0.389
NOTCH3	Q9UM47-1.2	L829P	Neutral	0.381
NOTCH3	Q9UM47-1.2	L829Q	Neutral	0.13
NOTCH3	Q9UM47-1.2	L829R	Neutral	0.125
NOTCH3	Q9UM47-1.2	L829S	Neutral	0.113
NOTCH3	Q9UM47-1.2	L829T	Neutral	0.029
NOTCH3	Q9UM47-1.2	L829V	Neutral	0.002
NOTCH3	Q9UM47-1.2	L829W	Neutral	0.117
NOTCH3	Q9UM47-1.2	L829Y	Neutral	0.031
NOTCH3	Q9UM47-1.2	A830C	Neutral	0.001
NOTCH3	Q9UM47-1.2	A830D	Neutral	0.027
NOTCH3	Q9UM47-1.2	A830E	Neutral	0.006
NOTCH3	Q9UM47-1.2	A830F	Neutral	0.023
NOTCH3	Q9UM47-1.2	A830G	Neutral	0.001
NOTCH3	Q9UM47-1.2	A830H	Neutral	0.024
NOTCH3	Q9UM47-1.2	A830I	Neutral	0.005
NOTCH3	Q9UM47-1.2	A830K	Neutral	0.005
NOTCH3	Q9UM47-1.2	A830L	Neutral	0.005
NOTCH3	Q9UM47-1.2	A830M	Neutral	0.005
NOTCH3	Q9UM47-1.2	A830N	Neutral	0.026
NOTCH3	Q9UM47-1.2	A830P	Neutral	0.006
NOTCH3	Q9UM47-1.2	A830Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	A830R	Neutral	0.005
NOTCH3	Q9UM47-1.2	A830S	Neutral	0.0
NOTCH3	Q9UM47-1.2	A830T	Neutral	0.001
NOTCH3	Q9UM47-1.2	A830V	Neutral	0.001
NOTCH3	Q9UM47-1.2	A830W	Neutral	0.088
NOTCH3	Q9UM47-1.2	A830Y	Neutral	0.022
NOTCH3	Q9UM47-1.2	G831A	Neutral	0.244
NOTCH3	Q9UM47-1.2	G831C	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	G831D	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	G831E	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	G831F	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G831H	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G831I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G831K	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	G831L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G831M	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G831N	Neutral	0.225
NOTCH3	Q9UM47-1.2	G831P	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	G831Q	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G831R	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	G831S	Neutral	0.239
NOTCH3	Q9UM47-1.2	G831T	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	G831V	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G831W	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G831Y	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	S832A	Neutral	0.023
NOTCH3	Q9UM47-1.2	S832C	Neutral	0.322
NOTCH3	Q9UM47-1.2	S832D	Neutral	0.093
NOTCH3	Q9UM47-1.2	S832E	Neutral	0.087
NOTCH3	Q9UM47-1.2	S832F	Pathogenic	0.643
NOTCH3	Q9UM47-1.2	S832G	Neutral	0.09
NOTCH3	Q9UM47-1.2	S832H	Neutral	0.294
NOTCH3	Q9UM47-1.2	S832I	Pathogenic	0.652
NOTCH3	Q9UM47-1.2	S832K	Neutral	0.079
NOTCH3	Q9UM47-1.2	S832L	Pathogenic	0.652
NOTCH3	Q9UM47-1.2	S832M	Neutral	0.291
NOTCH3	Q9UM47-1.2	S832N	Neutral	0.021
NOTCH3	Q9UM47-1.2	S832P	Neutral	0.318
NOTCH3	Q9UM47-1.2	S832Q	Neutral	0.085
NOTCH3	Q9UM47-1.2	S832R	Neutral	0.272
NOTCH3	Q9UM47-1.2	S832T	Neutral	0.022
NOTCH3	Q9UM47-1.2	S832V	Pathogenic	0.668
NOTCH3	Q9UM47-1.2	S832W	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	S832Y	Pathogenic	0.636
NOTCH3	Q9UM47-1.2	F833A	Pathogenic	0.671
NOTCH3	Q9UM47-1.2	F833C	Pathogenic	0.686
NOTCH3	Q9UM47-1.2	F833D	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	F833E	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	F833G	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	F833H	Neutral	0.354
NOTCH3	Q9UM47-1.2	F833I	Neutral	0.108
NOTCH3	Q9UM47-1.2	F833K	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	F833L	Neutral	0.108
NOTCH3	Q9UM47-1.2	F833M	Neutral	0.109
NOTCH3	Q9UM47-1.2	F833N	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	F833P	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	F833Q	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	F833R	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	F833S	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	F833T	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	F833V	Neutral	0.34
NOTCH3	Q9UM47-1.2	F833W	Neutral	0.024
NOTCH3	Q9UM47-1.2	F833Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	S834A	Neutral	0.0
NOTCH3	Q9UM47-1.2	S834C	Neutral	0.007
NOTCH3	Q9UM47-1.2	S834D	Neutral	0.002
NOTCH3	Q9UM47-1.2	S834E	Neutral	0.001
NOTCH3	Q9UM47-1.2	S834F	Neutral	0.027
NOTCH3	Q9UM47-1.2	S834G	Neutral	0.002
NOTCH3	Q9UM47-1.2	S834H	Neutral	0.006
NOTCH3	Q9UM47-1.2	S834I	Neutral	0.028
NOTCH3	Q9UM47-1.2	S834K	Neutral	0.001
NOTCH3	Q9UM47-1.2	S834L	Neutral	0.028
NOTCH3	Q9UM47-1.2	S834M	Neutral	0.006
NOTCH3	Q9UM47-1.2	S834N	Neutral	0.0
NOTCH3	Q9UM47-1.2	S834P	Neutral	0.007
NOTCH3	Q9UM47-1.2	S834Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	S834R	Neutral	0.006
NOTCH3	Q9UM47-1.2	S834T	Neutral	0.0
NOTCH3	Q9UM47-1.2	S834V	Neutral	0.03
NOTCH3	Q9UM47-1.2	S834W	Neutral	0.101
NOTCH3	Q9UM47-1.2	S834Y	Neutral	0.026
NOTCH3	Q9UM47-1.2	C835A	Neutral	0.496
NOTCH3	Q9UM47-1.2	C835D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C835E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C835F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	C835G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C835H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C835I	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C835K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C835L	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C835M	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	C835N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C835P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C835Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C835R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C835S	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C835T	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C835V	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	C835W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C835Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	T836A	Neutral	0.002
NOTCH3	Q9UM47-1.2	T836C	Neutral	0.009
NOTCH3	Q9UM47-1.2	T836D	Neutral	0.009
NOTCH3	Q9UM47-1.2	T836E	Neutral	0.009
NOTCH3	Q9UM47-1.2	T836F	Neutral	0.035
NOTCH3	Q9UM47-1.2	T836G	Neutral	0.034
NOTCH3	Q9UM47-1.2	T836H	Neutral	0.037
NOTCH3	Q9UM47-1.2	T836I	Neutral	0.008
NOTCH3	Q9UM47-1.2	T836K	Neutral	0.008
NOTCH3	Q9UM47-1.2	T836L	Neutral	0.008
NOTCH3	Q9UM47-1.2	T836M	Neutral	0.008
NOTCH3	Q9UM47-1.2	T836N	Neutral	0.002
NOTCH3	Q9UM47-1.2	T836P	Neutral	0.009
NOTCH3	Q9UM47-1.2	T836Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	T836R	Neutral	0.007
NOTCH3	Q9UM47-1.2	T836S	Neutral	0.0
NOTCH3	Q9UM47-1.2	T836V	Neutral	0.002
NOTCH3	Q9UM47-1.2	T836W	Neutral	0.032
NOTCH3	Q9UM47-1.2	T836Y	Neutral	0.034
NOTCH3	Q9UM47-1.2	C837A	Pathogenic	0.503
NOTCH3	Q9UM47-1.2	C837D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C837E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C837F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	C837G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C837H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C837I	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C837K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C837L	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C837M	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C837N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C837P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C837Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C837R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C837S	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C837T	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	C837V	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	C837W	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	C837Y	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	H838A	Neutral	0.157
NOTCH3	Q9UM47-1.2	H838C	Neutral	0.478
NOTCH3	Q9UM47-1.2	H838D	Neutral	0.043
NOTCH3	Q9UM47-1.2	H838E	Neutral	0.01
NOTCH3	Q9UM47-1.2	H838F	Neutral	0.045
NOTCH3	Q9UM47-1.2	H838G	Neutral	0.147
NOTCH3	Q9UM47-1.2	H838I	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	H838K	Neutral	0.045
NOTCH3	Q9UM47-1.2	H838L	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	H838M	Neutral	0.182
NOTCH3	Q9UM47-1.2	H838N	Neutral	0.002
NOTCH3	Q9UM47-1.2	H838P	Neutral	0.169
NOTCH3	Q9UM47-1.2	H838Q	Neutral	0.011
NOTCH3	Q9UM47-1.2	H838R	Neutral	0.01
NOTCH3	Q9UM47-1.2	H838S	Neutral	0.04
NOTCH3	Q9UM47-1.2	H838T	Neutral	0.17
NOTCH3	Q9UM47-1.2	H838V	Neutral	0.497
NOTCH3	Q9UM47-1.2	H838W	Neutral	0.162
NOTCH3	Q9UM47-1.2	H838Y	Neutral	0.0
NOTCH3	Q9UM47-1.2	G839A	Neutral	0.0
NOTCH3	Q9UM47-1.2	G839C	Neutral	0.034
NOTCH3	Q9UM47-1.2	G839D	Neutral	0.002
NOTCH3	Q9UM47-1.2	G839E	Neutral	0.007
NOTCH3	Q9UM47-1.2	G839F	Neutral	0.029
NOTCH3	Q9UM47-1.2	G839H	Neutral	0.007
NOTCH3	Q9UM47-1.2	G839I	Neutral	0.123
NOTCH3	Q9UM47-1.2	G839K	Neutral	0.006
NOTCH3	Q9UM47-1.2	G839L	Neutral	0.123
NOTCH3	Q9UM47-1.2	G839M	Neutral	0.03
NOTCH3	Q9UM47-1.2	G839N	Neutral	0.0
NOTCH3	Q9UM47-1.2	G839P	Neutral	0.008
NOTCH3	Q9UM47-1.2	G839Q	Neutral	0.007
NOTCH3	Q9UM47-1.2	G839R	Neutral	0.006
NOTCH3	Q9UM47-1.2	G839S	Neutral	0.0
NOTCH3	Q9UM47-1.2	G839T	Neutral	0.007
NOTCH3	Q9UM47-1.2	G839V	Neutral	0.032
NOTCH3	Q9UM47-1.2	G839W	Neutral	0.006
NOTCH3	Q9UM47-1.2	G839Y	Neutral	0.028
NOTCH3	Q9UM47-1.2	G840A	Neutral	0.228
NOTCH3	Q9UM47-1.2	G840C	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G840D	Pathogenic	0.552
NOTCH3	Q9UM47-1.2	G840E	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	G840F	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G840H	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	G840I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G840K	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	G840L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G840M	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G840N	Neutral	0.21
NOTCH3	Q9UM47-1.2	G840P	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	G840Q	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	G840R	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	G840S	Neutral	0.224
NOTCH3	Q9UM47-1.2	G840T	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	G840V	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G840W	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	G840Y	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	Y841A	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	Y841C	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	Y841D	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	Y841E	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	Y841F	Neutral	0.007
NOTCH3	Q9UM47-1.2	Y841G	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	Y841H	Neutral	0.029
NOTCH3	Q9UM47-1.2	Y841I	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	Y841K	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	Y841L	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	Y841M	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	Y841N	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	Y841P	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	Y841Q	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	Y841R	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	Y841S	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	Y841T	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	Y841V	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	Y841W	Neutral	0.03
NOTCH3	Q9UM47-1.2	T842A	Neutral	0.05
NOTCH3	Q9UM47-1.2	T842C	Neutral	0.207
NOTCH3	Q9UM47-1.2	T842D	Neutral	0.211
NOTCH3	Q9UM47-1.2	T842E	Neutral	0.202
NOTCH3	Q9UM47-1.2	T842F	Pathogenic	0.511
NOTCH3	Q9UM47-1.2	T842G	Pathogenic	0.505
NOTCH3	Q9UM47-1.2	T842H	Pathogenic	0.524
NOTCH3	Q9UM47-1.2	T842I	Neutral	0.193
NOTCH3	Q9UM47-1.2	T842K	Neutral	0.186
NOTCH3	Q9UM47-1.2	T842L	Neutral	0.193
NOTCH3	Q9UM47-1.2	T842M	Neutral	0.193
NOTCH3	Q9UM47-1.2	T842N	Neutral	0.055
NOTCH3	Q9UM47-1.2	T842P	Neutral	0.209
NOTCH3	Q9UM47-1.2	T842Q	Neutral	0.198
NOTCH3	Q9UM47-1.2	T842R	Neutral	0.179
NOTCH3	Q9UM47-1.2	T842S	Neutral	0.012
NOTCH3	Q9UM47-1.2	T842V	Neutral	0.053
NOTCH3	Q9UM47-1.2	T842W	Neutral	0.485
NOTCH3	Q9UM47-1.2	T842Y	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	G843A	Neutral	0.244
NOTCH3	Q9UM47-1.2	G843C	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	G843D	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	G843E	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	G843F	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G843H	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G843I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G843K	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	G843L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G843M	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G843N	Neutral	0.225
NOTCH3	Q9UM47-1.2	G843P	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	G843Q	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G843R	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	G843S	Neutral	0.239
NOTCH3	Q9UM47-1.2	G843T	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	G843V	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G843W	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G843Y	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	P844A	Neutral	0.01
NOTCH3	Q9UM47-1.2	P844C	Neutral	0.182
NOTCH3	Q9UM47-1.2	P844D	Neutral	0.011
NOTCH3	Q9UM47-1.2	P844E	Neutral	0.01
NOTCH3	Q9UM47-1.2	P844F	Neutral	0.466
NOTCH3	Q9UM47-1.2	P844G	Neutral	0.041
NOTCH3	Q9UM47-1.2	P844H	Neutral	0.043
NOTCH3	Q9UM47-1.2	P844I	Neutral	0.167
NOTCH3	Q9UM47-1.2	P844K	Neutral	0.009
NOTCH3	Q9UM47-1.2	P844L	Neutral	0.166
NOTCH3	Q9UM47-1.2	P844M	Neutral	0.042
NOTCH3	Q9UM47-1.2	P844N	Neutral	0.047
NOTCH3	Q9UM47-1.2	P844Q	Neutral	0.01
NOTCH3	Q9UM47-1.2	P844R	Neutral	0.039
NOTCH3	Q9UM47-1.2	P844S	Neutral	0.01
NOTCH3	Q9UM47-1.2	P844T	Neutral	0.011
NOTCH3	Q9UM47-1.2	P844V	Neutral	0.045
NOTCH3	Q9UM47-1.2	P844W	Neutral	0.44
NOTCH3	Q9UM47-1.2	P844Y	Neutral	0.157
NOTCH3	Q9UM47-1.2	S845A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S845C	Neutral	0.013
NOTCH3	Q9UM47-1.2	S845D	Neutral	0.003
NOTCH3	Q9UM47-1.2	S845E	Neutral	0.003
NOTCH3	Q9UM47-1.2	S845F	Neutral	0.049
NOTCH3	Q9UM47-1.2	S845G	Neutral	0.003
NOTCH3	Q9UM47-1.2	S845H	Neutral	0.012
NOTCH3	Q9UM47-1.2	S845I	Neutral	0.051
NOTCH3	Q9UM47-1.2	S845K	Neutral	0.002
NOTCH3	Q9UM47-1.2	S845L	Neutral	0.051
NOTCH3	Q9UM47-1.2	S845M	Neutral	0.012
NOTCH3	Q9UM47-1.2	S845N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S845P	Neutral	0.013
NOTCH3	Q9UM47-1.2	S845Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	S845R	Neutral	0.011
NOTCH3	Q9UM47-1.2	S845T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S845V	Neutral	0.054
NOTCH3	Q9UM47-1.2	S845W	Neutral	0.174
NOTCH3	Q9UM47-1.2	S845Y	Neutral	0.048
NOTCH3	Q9UM47-1.2	C846A	Neutral	0.496
NOTCH3	Q9UM47-1.2	C846D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C846E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C846F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	C846G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C846H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C846I	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C846K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C846L	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C846M	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	C846N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C846P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C846Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C846R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C846S	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C846T	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C846V	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	C846W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C846Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	D847A	Neutral	0.241
NOTCH3	Q9UM47-1.2	D847C	Pathogenic	0.609
NOTCH3	Q9UM47-1.2	D847E	Neutral	0.001
NOTCH3	Q9UM47-1.2	D847F	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	D847G	Neutral	0.061
NOTCH3	Q9UM47-1.2	D847H	Neutral	0.064
NOTCH3	Q9UM47-1.2	D847I	Pathogenic	0.585
NOTCH3	Q9UM47-1.2	D847K	Neutral	0.06
NOTCH3	Q9UM47-1.2	D847L	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	D847M	Pathogenic	0.584
NOTCH3	Q9UM47-1.2	D847N	Neutral	0.004
NOTCH3	Q9UM47-1.2	D847P	Neutral	0.071
NOTCH3	Q9UM47-1.2	D847Q	Neutral	0.015
NOTCH3	Q9UM47-1.2	D847R	Neutral	0.217
NOTCH3	Q9UM47-1.2	D847S	Neutral	0.015
NOTCH3	Q9UM47-1.2	D847T	Neutral	0.07
NOTCH3	Q9UM47-1.2	D847V	Pathogenic	0.602
NOTCH3	Q9UM47-1.2	D847W	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	D847Y	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	Q848A	Neutral	0.02
NOTCH3	Q9UM47-1.2	Q848C	Neutral	0.317
NOTCH3	Q9UM47-1.2	Q848D	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q848E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q848F	Neutral	0.324
NOTCH3	Q9UM47-1.2	Q848G	Neutral	0.08
NOTCH3	Q9UM47-1.2	Q848H	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q848I	Neutral	0.334
NOTCH3	Q9UM47-1.2	Q848K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q848L	Neutral	0.099
NOTCH3	Q9UM47-1.2	Q848M	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q848N	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q848P	Neutral	0.022
NOTCH3	Q9UM47-1.2	Q848R	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q848S	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q848T	Neutral	0.022
NOTCH3	Q9UM47-1.2	Q848V	Neutral	0.099
NOTCH3	Q9UM47-1.2	Q848W	Neutral	0.087
NOTCH3	Q9UM47-1.2	Q848Y	Neutral	0.022
NOTCH3	Q9UM47-1.2	D849A	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	D849C	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	D849E	Neutral	0.011
NOTCH3	Q9UM47-1.2	D849F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	D849G	Neutral	0.485
NOTCH3	Q9UM47-1.2	D849H	Pathogenic	0.501
NOTCH3	Q9UM47-1.2	D849I	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	D849K	Neutral	0.483
NOTCH3	Q9UM47-1.2	D849L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	D849M	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	D849N	Neutral	0.05
NOTCH3	Q9UM47-1.2	D849P	Pathogenic	0.527
NOTCH3	Q9UM47-1.2	D849Q	Neutral	0.183
NOTCH3	Q9UM47-1.2	D849R	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	D849S	Neutral	0.186
NOTCH3	Q9UM47-1.2	D849T	Pathogenic	0.525
NOTCH3	Q9UM47-1.2	D849V	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	D849W	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	D849Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	I850A	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	I850C	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	I850D	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	I850E	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	I850F	Neutral	0.442
NOTCH3	Q9UM47-1.2	I850G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I850H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	I850K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	I850L	Neutral	0.038
NOTCH3	Q9UM47-1.2	I850M	Neutral	0.154
NOTCH3	Q9UM47-1.2	I850N	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	I850P	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	I850Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	I850R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	I850S	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	I850T	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	I850V	Neutral	0.008
NOTCH3	Q9UM47-1.2	I850W	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	I850Y	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	N851A	Neutral	0.249
NOTCH3	Q9UM47-1.2	N851C	Pathogenic	0.62
NOTCH3	Q9UM47-1.2	N851D	Neutral	0.004
NOTCH3	Q9UM47-1.2	N851E	Neutral	0.017
NOTCH3	Q9UM47-1.2	N851F	Pathogenic	0.595
NOTCH3	Q9UM47-1.2	N851G	Neutral	0.015
NOTCH3	Q9UM47-1.2	N851H	Neutral	0.004
NOTCH3	Q9UM47-1.2	N851I	Pathogenic	0.605
NOTCH3	Q9UM47-1.2	N851K	Neutral	0.015
NOTCH3	Q9UM47-1.2	N851L	Pathogenic	0.605
NOTCH3	Q9UM47-1.2	N851M	Neutral	0.251
NOTCH3	Q9UM47-1.2	N851P	Neutral	0.266
NOTCH3	Q9UM47-1.2	N851Q	Neutral	0.016
NOTCH3	Q9UM47-1.2	N851R	Neutral	0.014
NOTCH3	Q9UM47-1.2	N851S	Neutral	0.004
NOTCH3	Q9UM47-1.2	N851T	Neutral	0.017
NOTCH3	Q9UM47-1.2	N851V	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	N851W	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	N851Y	Neutral	0.238
NOTCH3	Q9UM47-1.2	D852A	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	D852C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D852E	Neutral	0.031
NOTCH3	Q9UM47-1.2	D852F	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D852G	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	D852H	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	D852I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D852K	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	D852L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D852M	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D852N	Neutral	0.133
NOTCH3	Q9UM47-1.2	D852P	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	D852Q	Neutral	0.395
NOTCH3	Q9UM47-1.2	D852R	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	D852S	Neutral	0.4
NOTCH3	Q9UM47-1.2	D852T	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	D852V	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D852W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D852Y	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	C853A	Pathogenic	0.503
NOTCH3	Q9UM47-1.2	C853D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C853E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C853F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	C853G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C853H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C853I	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C853K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C853L	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C853M	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C853N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C853P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C853Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C853R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C853S	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C853T	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	C853V	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	C853W	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	C853Y	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	D854A	Neutral	0.041
NOTCH3	Q9UM47-1.2	D854C	Neutral	0.173
NOTCH3	Q9UM47-1.2	D854E	Neutral	0.0
NOTCH3	Q9UM47-1.2	D854F	Neutral	0.154
NOTCH3	Q9UM47-1.2	D854G	Neutral	0.009
NOTCH3	Q9UM47-1.2	D854H	Neutral	0.009
NOTCH3	Q9UM47-1.2	D854I	Neutral	0.159
NOTCH3	Q9UM47-1.2	D854K	Neutral	0.009
NOTCH3	Q9UM47-1.2	D854L	Neutral	0.463
NOTCH3	Q9UM47-1.2	D854M	Neutral	0.159
NOTCH3	Q9UM47-1.2	D854N	Neutral	0.0
NOTCH3	Q9UM47-1.2	D854P	Neutral	0.01
NOTCH3	Q9UM47-1.2	D854Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	D854R	Neutral	0.036
NOTCH3	Q9UM47-1.2	D854S	Neutral	0.002
NOTCH3	Q9UM47-1.2	D854T	Neutral	0.01
NOTCH3	Q9UM47-1.2	D854V	Neutral	0.169
NOTCH3	Q9UM47-1.2	D854W	Neutral	0.427
NOTCH3	Q9UM47-1.2	D854Y	Neutral	0.15
NOTCH3	Q9UM47-1.2	P855A	Neutral	0.282
NOTCH3	Q9UM47-1.2	P855C	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	P855D	Neutral	0.302
NOTCH3	Q9UM47-1.2	P855E	Neutral	0.287
NOTCH3	Q9UM47-1.2	P855F	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	P855G	Pathogenic	0.625
NOTCH3	Q9UM47-1.2	P855H	Pathogenic	0.638
NOTCH3	Q9UM47-1.2	P855I	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	P855K	Neutral	0.268
NOTCH3	Q9UM47-1.2	P855L	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	P855M	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	P855N	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	P855Q	Neutral	0.283
NOTCH3	Q9UM47-1.2	P855R	Pathogenic	0.613
NOTCH3	Q9UM47-1.2	P855S	Neutral	0.288
NOTCH3	Q9UM47-1.2	P855T	Neutral	0.298
NOTCH3	Q9UM47-1.2	P855V	Pathogenic	0.649
NOTCH3	Q9UM47-1.2	P855W	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	P855Y	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	N856A	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	N856C	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	N856D	Neutral	0.065
NOTCH3	Q9UM47-1.2	N856E	Neutral	0.236
NOTCH3	Q9UM47-1.2	N856F	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	N856G	Neutral	0.213
NOTCH3	Q9UM47-1.2	N856H	Neutral	0.062
NOTCH3	Q9UM47-1.2	N856I	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	N856K	Neutral	0.219
NOTCH3	Q9UM47-1.2	N856L	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	N856M	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	N856P	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	N856Q	Neutral	0.233
NOTCH3	Q9UM47-1.2	N856R	Neutral	0.21
NOTCH3	Q9UM47-1.2	N856S	Neutral	0.061
NOTCH3	Q9UM47-1.2	N856T	Neutral	0.244
NOTCH3	Q9UM47-1.2	N856V	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	N856W	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	N856Y	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	P857A	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	P857C	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	P857D	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	P857E	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	P857F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P857G	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	P857H	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	P857I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P857K	Pathogenic	0.673
NOTCH3	Q9UM47-1.2	P857L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P857M	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	P857N	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	P857Q	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	P857R	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	P857S	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	P857T	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	P857V	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	P857W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P857Y	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	C858A	Neutral	0.495
NOTCH3	Q9UM47-1.2	C858D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C858E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C858F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	C858G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C858H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C858I	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	C858K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C858L	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	C858M	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C858N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C858P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C858Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C858R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C858S	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	C858T	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	C858V	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	C858W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C858Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	L859A	Neutral	0.049
NOTCH3	Q9UM47-1.2	L859C	Neutral	0.053
NOTCH3	Q9UM47-1.2	L859D	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	L859E	Pathogenic	0.56
NOTCH3	Q9UM47-1.2	L859F	Neutral	0.013
NOTCH3	Q9UM47-1.2	L859G	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	L859H	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	L859I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L859K	Neutral	0.222
NOTCH3	Q9UM47-1.2	L859M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L859N	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	L859P	Pathogenic	0.539
NOTCH3	Q9UM47-1.2	L859Q	Neutral	0.221
NOTCH3	Q9UM47-1.2	L859R	Neutral	0.213
NOTCH3	Q9UM47-1.2	L859S	Neutral	0.195
NOTCH3	Q9UM47-1.2	L859T	Neutral	0.054
NOTCH3	Q9UM47-1.2	L859V	Neutral	0.003
NOTCH3	Q9UM47-1.2	L859W	Neutral	0.201
NOTCH3	Q9UM47-1.2	L859Y	Neutral	0.057
NOTCH3	Q9UM47-1.2	N860A	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	N860C	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	N860D	Neutral	0.118
NOTCH3	Q9UM47-1.2	N860E	Neutral	0.371
NOTCH3	Q9UM47-1.2	N860F	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	N860G	Neutral	0.341
NOTCH3	Q9UM47-1.2	N860H	Neutral	0.112
NOTCH3	Q9UM47-1.2	N860I	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	N860K	Neutral	0.349
NOTCH3	Q9UM47-1.2	N860L	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	N860M	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	N860P	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	N860Q	Neutral	0.367
NOTCH3	Q9UM47-1.2	N860R	Neutral	0.337
NOTCH3	Q9UM47-1.2	N860S	Neutral	0.111
NOTCH3	Q9UM47-1.2	N860T	Neutral	0.382
NOTCH3	Q9UM47-1.2	N860V	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	N860W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	N860Y	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	G861A	Neutral	0.225
NOTCH3	Q9UM47-1.2	G861C	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	G861D	Pathogenic	0.547
NOTCH3	Q9UM47-1.2	G861E	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G861F	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G861H	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	G861I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G861K	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	G861L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G861M	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G861N	Neutral	0.206
NOTCH3	Q9UM47-1.2	G861P	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	G861Q	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	G861R	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	G861S	Neutral	0.22
NOTCH3	Q9UM47-1.2	G861T	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	G861V	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G861W	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	G861Y	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G862A	Neutral	0.153
NOTCH3	Q9UM47-1.2	G862C	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	G862D	Neutral	0.43
NOTCH3	Q9UM47-1.2	G862E	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	G862F	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	G862H	Pathogenic	0.755
NOTCH3	Q9UM47-1.2	G862I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	G862K	Pathogenic	0.744
NOTCH3	Q9UM47-1.2	G862L	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	G862M	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	G862N	Neutral	0.14
NOTCH3	Q9UM47-1.2	G862P	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	G862Q	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	G862R	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	G862S	Neutral	0.15
NOTCH3	Q9UM47-1.2	G862T	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	G862V	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	G862W	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	G862Y	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	S863A	Neutral	0.024
NOTCH3	Q9UM47-1.2	S863C	Neutral	0.33
NOTCH3	Q9UM47-1.2	S863D	Neutral	0.096
NOTCH3	Q9UM47-1.2	S863E	Neutral	0.09
NOTCH3	Q9UM47-1.2	S863F	Pathogenic	0.651
NOTCH3	Q9UM47-1.2	S863G	Neutral	0.093
NOTCH3	Q9UM47-1.2	S863H	Neutral	0.301
NOTCH3	Q9UM47-1.2	S863I	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	S863K	Neutral	0.082
NOTCH3	Q9UM47-1.2	S863L	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	S863M	Neutral	0.298
NOTCH3	Q9UM47-1.2	S863N	Neutral	0.022
NOTCH3	Q9UM47-1.2	S863P	Neutral	0.326
NOTCH3	Q9UM47-1.2	S863Q	Neutral	0.088
NOTCH3	Q9UM47-1.2	S863R	Neutral	0.279
NOTCH3	Q9UM47-1.2	S863T	Neutral	0.022
NOTCH3	Q9UM47-1.2	S863V	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	S863W	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	S863Y	Pathogenic	0.644
NOTCH3	Q9UM47-1.2	C864A	Neutral	0.491
NOTCH3	Q9UM47-1.2	C864D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C864E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C864F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C864G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C864H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C864I	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C864K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C864L	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C864M	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C864N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C864P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C864Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C864R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C864S	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C864T	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C864V	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C864W	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	C864Y	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	Q865A	Neutral	0.021
NOTCH3	Q9UM47-1.2	Q865C	Neutral	0.324
NOTCH3	Q9UM47-1.2	Q865D	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q865E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q865F	Neutral	0.331
NOTCH3	Q9UM47-1.2	Q865G	Neutral	0.083
NOTCH3	Q9UM47-1.2	Q865H	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q865I	Neutral	0.341
NOTCH3	Q9UM47-1.2	Q865K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q865L	Neutral	0.102
NOTCH3	Q9UM47-1.2	Q865M	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q865N	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q865P	Neutral	0.023
NOTCH3	Q9UM47-1.2	Q865R	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q865S	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q865T	Neutral	0.023
NOTCH3	Q9UM47-1.2	Q865V	Neutral	0.102
NOTCH3	Q9UM47-1.2	Q865W	Neutral	0.089
NOTCH3	Q9UM47-1.2	Q865Y	Neutral	0.023
NOTCH3	Q9UM47-1.2	D866A	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	D866C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D866E	Neutral	0.033
NOTCH3	Q9UM47-1.2	D866F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D866G	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	D866H	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	D866I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D866K	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	D866L	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	D866M	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D866N	Neutral	0.142
NOTCH3	Q9UM47-1.2	D866P	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	D866Q	Neutral	0.413
NOTCH3	Q9UM47-1.2	D866R	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	D866S	Neutral	0.418
NOTCH3	Q9UM47-1.2	D866T	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	D866V	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D866W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D866Y	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	G867A	Neutral	0.06
NOTCH3	Q9UM47-1.2	G867C	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	G867D	Neutral	0.209
NOTCH3	Q9UM47-1.2	G867E	Pathogenic	0.529
NOTCH3	Q9UM47-1.2	G867F	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G867H	Pathogenic	0.52
NOTCH3	Q9UM47-1.2	G867I	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G867K	Pathogenic	0.505
NOTCH3	Q9UM47-1.2	G867L	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G867M	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G867N	Neutral	0.054
NOTCH3	Q9UM47-1.2	G867P	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	G867Q	Pathogenic	0.524
NOTCH3	Q9UM47-1.2	G867R	Neutral	0.492
NOTCH3	Q9UM47-1.2	G867S	Neutral	0.058
NOTCH3	Q9UM47-1.2	G867T	Pathogenic	0.544
NOTCH3	Q9UM47-1.2	G867V	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	G867W	Neutral	0.481
NOTCH3	Q9UM47-1.2	G867Y	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	V868A	Neutral	0.154
NOTCH3	Q9UM47-1.2	V868C	Neutral	0.471
NOTCH3	Q9UM47-1.2	V868D	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	V868E	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	V868F	Neutral	0.461
NOTCH3	Q9UM47-1.2	V868G	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	V868H	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	V868I	Neutral	0.002
NOTCH3	Q9UM47-1.2	V868K	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	V868L	Neutral	0.041
NOTCH3	Q9UM47-1.2	V868M	Neutral	0.041
NOTCH3	Q9UM47-1.2	V868N	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	V868P	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	V868Q	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	V868R	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	V868S	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	V868T	Neutral	0.168
NOTCH3	Q9UM47-1.2	V868W	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	V868Y	Neutral	0.454
NOTCH3	Q9UM47-1.2	G869A	Neutral	0.011
NOTCH3	Q9UM47-1.2	G869C	Neutral	0.494
NOTCH3	Q9UM47-1.2	G869D	Neutral	0.044
NOTCH3	Q9UM47-1.2	G869E	Neutral	0.164
NOTCH3	Q9UM47-1.2	G869F	Neutral	0.449
NOTCH3	Q9UM47-1.2	G869H	Neutral	0.159
NOTCH3	Q9UM47-1.2	G869I	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	G869K	Neutral	0.151
NOTCH3	Q9UM47-1.2	G869L	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	G869M	Neutral	0.458
NOTCH3	Q9UM47-1.2	G869N	Neutral	0.01
NOTCH3	Q9UM47-1.2	G869P	Neutral	0.174
NOTCH3	Q9UM47-1.2	G869Q	Neutral	0.161
NOTCH3	Q9UM47-1.2	G869R	Neutral	0.145
NOTCH3	Q9UM47-1.2	G869S	Neutral	0.011
NOTCH3	Q9UM47-1.2	G869T	Neutral	0.172
NOTCH3	Q9UM47-1.2	G869V	Neutral	0.476
NOTCH3	Q9UM47-1.2	G869W	Neutral	0.139
NOTCH3	Q9UM47-1.2	G869Y	Neutral	0.441
NOTCH3	Q9UM47-1.2	S870A	Neutral	0.004
NOTCH3	Q9UM47-1.2	S870C	Neutral	0.076
NOTCH3	Q9UM47-1.2	S870D	Neutral	0.017
NOTCH3	Q9UM47-1.2	S870E	Neutral	0.016
NOTCH3	Q9UM47-1.2	S870F	Neutral	0.239
NOTCH3	Q9UM47-1.2	S870G	Neutral	0.017
NOTCH3	Q9UM47-1.2	S870H	Neutral	0.068
NOTCH3	Q9UM47-1.2	S870I	Neutral	0.247
NOTCH3	Q9UM47-1.2	S870K	Neutral	0.015
NOTCH3	Q9UM47-1.2	S870L	Neutral	0.247
NOTCH3	Q9UM47-1.2	S870M	Neutral	0.067
NOTCH3	Q9UM47-1.2	S870N	Neutral	0.004
NOTCH3	Q9UM47-1.2	S870P	Neutral	0.075
NOTCH3	Q9UM47-1.2	S870Q	Neutral	0.016
NOTCH3	Q9UM47-1.2	S870R	Neutral	0.061
NOTCH3	Q9UM47-1.2	S870T	Neutral	0.004
NOTCH3	Q9UM47-1.2	S870V	Neutral	0.26
NOTCH3	Q9UM47-1.2	S870W	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	S870Y	Neutral	0.234
NOTCH3	Q9UM47-1.2	F871A	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	F871C	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	F871D	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	F871E	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	F871G	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	F871H	Pathogenic	0.788
NOTCH3	Q9UM47-1.2	F871I	Neutral	0.452
NOTCH3	Q9UM47-1.2	F871K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	F871L	Neutral	0.452
NOTCH3	Q9UM47-1.2	F871M	Neutral	0.453
NOTCH3	Q9UM47-1.2	F871N	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	F871P	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F871Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	F871R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	F871S	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	F871T	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	F871V	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	F871W	Neutral	0.145
NOTCH3	Q9UM47-1.2	F871Y	Neutral	0.009
NOTCH3	Q9UM47-1.2	S872A	Neutral	0.006
NOTCH3	Q9UM47-1.2	S872C	Neutral	0.107
NOTCH3	Q9UM47-1.2	S872D	Neutral	0.025
NOTCH3	Q9UM47-1.2	S872E	Neutral	0.023
NOTCH3	Q9UM47-1.2	S872F	Neutral	0.312
NOTCH3	Q9UM47-1.2	S872G	Neutral	0.024
NOTCH3	Q9UM47-1.2	S872H	Neutral	0.095
NOTCH3	Q9UM47-1.2	S872I	Neutral	0.321
NOTCH3	Q9UM47-1.2	S872K	Neutral	0.021
NOTCH3	Q9UM47-1.2	S872L	Neutral	0.321
NOTCH3	Q9UM47-1.2	S872M	Neutral	0.094
NOTCH3	Q9UM47-1.2	S872N	Neutral	0.005
NOTCH3	Q9UM47-1.2	S872P	Neutral	0.105
NOTCH3	Q9UM47-1.2	S872Q	Neutral	0.023
NOTCH3	Q9UM47-1.2	S872R	Neutral	0.086
NOTCH3	Q9UM47-1.2	S872T	Neutral	0.006
NOTCH3	Q9UM47-1.2	S872V	Neutral	0.336
NOTCH3	Q9UM47-1.2	S872W	Pathogenic	0.65
NOTCH3	Q9UM47-1.2	S872Y	Neutral	0.305
NOTCH3	Q9UM47-1.2	C873A	Pathogenic	0.5
NOTCH3	Q9UM47-1.2	C873D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C873E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C873F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	C873G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C873H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C873I	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C873K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C873L	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C873M	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C873N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C873P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C873Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C873R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C873S	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	C873T	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	C873V	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C873W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C873Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	S874A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S874C	Neutral	0.019
NOTCH3	Q9UM47-1.2	S874D	Neutral	0.004
NOTCH3	Q9UM47-1.2	S874E	Neutral	0.004
NOTCH3	Q9UM47-1.2	S874F	Neutral	0.07
NOTCH3	Q9UM47-1.2	S874G	Neutral	0.004
NOTCH3	Q9UM47-1.2	S874H	Neutral	0.017
NOTCH3	Q9UM47-1.2	S874I	Neutral	0.073
NOTCH3	Q9UM47-1.2	S874K	Neutral	0.004
NOTCH3	Q9UM47-1.2	S874L	Neutral	0.073
NOTCH3	Q9UM47-1.2	S874M	Neutral	0.017
NOTCH3	Q9UM47-1.2	S874N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S874P	Neutral	0.019
NOTCH3	Q9UM47-1.2	S874Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	S874R	Neutral	0.015
NOTCH3	Q9UM47-1.2	S874T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S874V	Neutral	0.077
NOTCH3	Q9UM47-1.2	S874W	Neutral	0.236
NOTCH3	Q9UM47-1.2	S874Y	Neutral	0.068
NOTCH3	Q9UM47-1.2	C875A	Pathogenic	0.5
NOTCH3	Q9UM47-1.2	C875D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C875E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C875F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	C875G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C875H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C875I	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C875K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C875L	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C875M	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C875N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C875P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C875Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C875R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C875S	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	C875T	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	C875V	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C875W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C875Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	L876A	Neutral	0.33
NOTCH3	Q9UM47-1.2	L876C	Neutral	0.346
NOTCH3	Q9UM47-1.2	L876D	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L876E	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	L876F	Neutral	0.114
NOTCH3	Q9UM47-1.2	L876G	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	L876H	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	L876I	Neutral	0.006
NOTCH3	Q9UM47-1.2	L876K	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	L876M	Neutral	0.006
NOTCH3	Q9UM47-1.2	L876N	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	L876P	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	L876Q	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	L876R	Pathogenic	0.721
NOTCH3	Q9UM47-1.2	L876S	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	L876T	Neutral	0.353
NOTCH3	Q9UM47-1.2	L876V	Neutral	0.027
NOTCH3	Q9UM47-1.2	L876W	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	L876Y	Neutral	0.364
NOTCH3	Q9UM47-1.2	P877A	Neutral	0.314
NOTCH3	Q9UM47-1.2	P877C	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	P877D	Neutral	0.334
NOTCH3	Q9UM47-1.2	P877E	Neutral	0.319
NOTCH3	Q9UM47-1.2	P877F	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	P877G	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	P877H	Pathogenic	0.672
NOTCH3	Q9UM47-1.2	P877I	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	P877K	Neutral	0.298
NOTCH3	Q9UM47-1.2	P877L	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	P877M	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	P877N	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	P877Q	Neutral	0.314
NOTCH3	Q9UM47-1.2	P877R	Pathogenic	0.648
NOTCH3	Q9UM47-1.2	P877S	Neutral	0.319
NOTCH3	Q9UM47-1.2	P877T	Neutral	0.331
NOTCH3	Q9UM47-1.2	P877V	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	P877W	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	P877Y	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	G878A	Neutral	0.241
NOTCH3	Q9UM47-1.2	G878C	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	G878D	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	G878E	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	G878F	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G878H	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	G878I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G878K	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	G878L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G878M	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G878N	Neutral	0.222
NOTCH3	Q9UM47-1.2	G878P	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	G878Q	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G878R	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G878S	Neutral	0.236
NOTCH3	Q9UM47-1.2	G878T	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	G878V	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G878W	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	G878Y	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	F879A	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	F879C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	F879D	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F879E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F879G	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F879H	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	F879I	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	F879K	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	F879L	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	F879M	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	F879N	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F879P	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	F879Q	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F879R	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F879S	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	F879T	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	F879V	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	F879W	Neutral	0.453
NOTCH3	Q9UM47-1.2	F879Y	Neutral	0.042
NOTCH3	Q9UM47-1.2	A880C	Neutral	0.002
NOTCH3	Q9UM47-1.2	A880D	Neutral	0.038
NOTCH3	Q9UM47-1.2	A880E	Neutral	0.008
NOTCH3	Q9UM47-1.2	A880F	Neutral	0.033
NOTCH3	Q9UM47-1.2	A880G	Neutral	0.002
NOTCH3	Q9UM47-1.2	A880H	Neutral	0.034
NOTCH3	Q9UM47-1.2	A880I	Neutral	0.008
NOTCH3	Q9UM47-1.2	A880K	Neutral	0.007
NOTCH3	Q9UM47-1.2	A880L	Neutral	0.008
NOTCH3	Q9UM47-1.2	A880M	Neutral	0.008
NOTCH3	Q9UM47-1.2	A880N	Neutral	0.038
NOTCH3	Q9UM47-1.2	A880P	Neutral	0.009
NOTCH3	Q9UM47-1.2	A880Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	A880R	Neutral	0.007
NOTCH3	Q9UM47-1.2	A880S	Neutral	0.0
NOTCH3	Q9UM47-1.2	A880T	Neutral	0.002
NOTCH3	Q9UM47-1.2	A880V	Neutral	0.002
NOTCH3	Q9UM47-1.2	A880W	Neutral	0.122
NOTCH3	Q9UM47-1.2	A880Y	Neutral	0.032
NOTCH3	Q9UM47-1.2	G881A	Neutral	0.232
NOTCH3	Q9UM47-1.2	G881C	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G881D	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	G881E	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	G881F	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G881H	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G881I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G881K	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G881L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G881M	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G881N	Neutral	0.213
NOTCH3	Q9UM47-1.2	G881P	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	G881Q	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	G881R	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	G881S	Neutral	0.227
NOTCH3	Q9UM47-1.2	G881T	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	G881V	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G881W	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	G881Y	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	P882A	Neutral	0.025
NOTCH3	Q9UM47-1.2	P882C	Neutral	0.364
NOTCH3	Q9UM47-1.2	P882D	Neutral	0.027
NOTCH3	Q9UM47-1.2	P882E	Neutral	0.026
NOTCH3	Q9UM47-1.2	P882F	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	P882G	Neutral	0.098
NOTCH3	Q9UM47-1.2	P882H	Neutral	0.103
NOTCH3	Q9UM47-1.2	P882I	Neutral	0.34
NOTCH3	Q9UM47-1.2	P882K	Neutral	0.023
NOTCH3	Q9UM47-1.2	P882L	Neutral	0.339
NOTCH3	Q9UM47-1.2	P882M	Neutral	0.101
NOTCH3	Q9UM47-1.2	P882N	Neutral	0.112
NOTCH3	Q9UM47-1.2	P882Q	Neutral	0.025
NOTCH3	Q9UM47-1.2	P882R	Neutral	0.094
NOTCH3	Q9UM47-1.2	P882S	Neutral	0.026
NOTCH3	Q9UM47-1.2	P882T	Neutral	0.027
NOTCH3	Q9UM47-1.2	P882V	Neutral	0.108
NOTCH3	Q9UM47-1.2	P882W	Pathogenic	0.669
NOTCH3	Q9UM47-1.2	P882Y	Neutral	0.324
NOTCH3	Q9UM47-1.2	R883A	Neutral	0.136
NOTCH3	Q9UM47-1.2	R883C	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	R883D	Neutral	0.438
NOTCH3	Q9UM47-1.2	R883E	Neutral	0.039
NOTCH3	Q9UM47-1.2	R883F	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	R883G	Neutral	0.399
NOTCH3	Q9UM47-1.2	R883H	Neutral	0.04
NOTCH3	Q9UM47-1.2	R883I	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	R883K	Neutral	0.002
NOTCH3	Q9UM47-1.2	R883L	Neutral	0.475
NOTCH3	Q9UM47-1.2	R883M	Neutral	0.165
NOTCH3	Q9UM47-1.2	R883N	Neutral	0.037
NOTCH3	Q9UM47-1.2	R883P	Neutral	0.44
NOTCH3	Q9UM47-1.2	R883Q	Neutral	0.009
NOTCH3	Q9UM47-1.2	R883S	Neutral	0.138
NOTCH3	Q9UM47-1.2	R883T	Neutral	0.148
NOTCH3	Q9UM47-1.2	R883V	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	R883W	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	R883Y	Neutral	0.49
NOTCH3	Q9UM47-1.2	C884A	Pathogenic	0.512
NOTCH3	Q9UM47-1.2	C884D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C884E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C884F	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	C884G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C884H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C884I	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C884K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C884L	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C884M	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C884N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C884P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C884Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C884R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C884S	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	C884T	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C884V	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C884W	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	C884Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	A885C	Neutral	0.011
NOTCH3	Q9UM47-1.2	A885D	Neutral	0.188
NOTCH3	Q9UM47-1.2	A885E	Neutral	0.045
NOTCH3	Q9UM47-1.2	A885F	Neutral	0.164
NOTCH3	Q9UM47-1.2	A885G	Neutral	0.011
NOTCH3	Q9UM47-1.2	A885H	Neutral	0.171
NOTCH3	Q9UM47-1.2	A885I	Neutral	0.043
NOTCH3	Q9UM47-1.2	A885K	Neutral	0.041
NOTCH3	Q9UM47-1.2	A885L	Neutral	0.043
NOTCH3	Q9UM47-1.2	A885M	Neutral	0.043
NOTCH3	Q9UM47-1.2	A885N	Neutral	0.185
NOTCH3	Q9UM47-1.2	A885P	Neutral	0.048
NOTCH3	Q9UM47-1.2	A885Q	Neutral	0.044
NOTCH3	Q9UM47-1.2	A885R	Neutral	0.039
NOTCH3	Q9UM47-1.2	A885S	Neutral	0.003
NOTCH3	Q9UM47-1.2	A885T	Neutral	0.011
NOTCH3	Q9UM47-1.2	A885V	Neutral	0.01
NOTCH3	Q9UM47-1.2	A885W	Neutral	0.445
NOTCH3	Q9UM47-1.2	A885Y	Neutral	0.16
NOTCH3	Q9UM47-1.2	R886A	Neutral	0.012
NOTCH3	Q9UM47-1.2	R886C	Neutral	0.208
NOTCH3	Q9UM47-1.2	R886D	Neutral	0.055
NOTCH3	Q9UM47-1.2	R886E	Neutral	0.003
NOTCH3	Q9UM47-1.2	R886F	Neutral	0.242
NOTCH3	Q9UM47-1.2	R886G	Neutral	0.047
NOTCH3	Q9UM47-1.2	R886H	Neutral	0.003
NOTCH3	Q9UM47-1.2	R886I	Neutral	0.234
NOTCH3	Q9UM47-1.2	R886K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R886L	Neutral	0.063
NOTCH3	Q9UM47-1.2	R886M	Neutral	0.014
NOTCH3	Q9UM47-1.2	R886N	Neutral	0.003
NOTCH3	Q9UM47-1.2	R886P	Neutral	0.055
NOTCH3	Q9UM47-1.2	R886Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	R886S	Neutral	0.012
NOTCH3	Q9UM47-1.2	R886T	Neutral	0.013
NOTCH3	Q9UM47-1.2	R886V	Neutral	0.22
NOTCH3	Q9UM47-1.2	R886W	Neutral	0.241
NOTCH3	Q9UM47-1.2	R886Y	Neutral	0.066
NOTCH3	Q9UM47-1.2	D887A	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	D887C	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	D887E	Neutral	0.016
NOTCH3	Q9UM47-1.2	D887F	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	D887G	Pathogenic	0.586
NOTCH3	Q9UM47-1.2	D887H	Pathogenic	0.602
NOTCH3	Q9UM47-1.2	D887I	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	D887K	Pathogenic	0.584
NOTCH3	Q9UM47-1.2	D887L	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	D887M	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	D887N	Neutral	0.073
NOTCH3	Q9UM47-1.2	D887P	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	D887Q	Neutral	0.251
NOTCH3	Q9UM47-1.2	D887R	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	D887S	Neutral	0.255
NOTCH3	Q9UM47-1.2	D887T	Pathogenic	0.625
NOTCH3	Q9UM47-1.2	D887V	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	D887W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	D887Y	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	V888A	Neutral	0.022
NOTCH3	Q9UM47-1.2	V888C	Neutral	0.1
NOTCH3	Q9UM47-1.2	V888D	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	V888E	Neutral	0.353
NOTCH3	Q9UM47-1.2	V888F	Neutral	0.097
NOTCH3	Q9UM47-1.2	V888G	Pathogenic	0.668
NOTCH3	Q9UM47-1.2	V888H	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	V888I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V888K	Neutral	0.331
NOTCH3	Q9UM47-1.2	V888L	Neutral	0.005
NOTCH3	Q9UM47-1.2	V888M	Neutral	0.005
NOTCH3	Q9UM47-1.2	V888N	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	V888P	Neutral	0.341
NOTCH3	Q9UM47-1.2	V888Q	Neutral	0.348
NOTCH3	Q9UM47-1.2	V888R	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	V888S	Neutral	0.328
NOTCH3	Q9UM47-1.2	V888T	Neutral	0.025
NOTCH3	Q9UM47-1.2	V888W	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	V888Y	Neutral	0.095
NOTCH3	Q9UM47-1.2	D889A	Neutral	0.419
NOTCH3	Q9UM47-1.2	D889C	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	D889E	Neutral	0.002
NOTCH3	Q9UM47-1.2	D889F	Pathogenic	0.755
NOTCH3	Q9UM47-1.2	D889G	Neutral	0.128
NOTCH3	Q9UM47-1.2	D889H	Neutral	0.135
NOTCH3	Q9UM47-1.2	D889I	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	D889K	Neutral	0.127
NOTCH3	Q9UM47-1.2	D889L	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	D889M	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	D889N	Neutral	0.008
NOTCH3	Q9UM47-1.2	D889P	Neutral	0.148
NOTCH3	Q9UM47-1.2	D889Q	Neutral	0.034
NOTCH3	Q9UM47-1.2	D889R	Neutral	0.387
NOTCH3	Q9UM47-1.2	D889S	Neutral	0.034
NOTCH3	Q9UM47-1.2	D889T	Neutral	0.147
NOTCH3	Q9UM47-1.2	D889V	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	D889W	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	D889Y	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	E890A	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	E890C	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	E890D	Neutral	0.049
NOTCH3	Q9UM47-1.2	E890F	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	E890G	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	E890H	Pathogenic	0.526
NOTCH3	Q9UM47-1.2	E890I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	E890K	Neutral	0.185
NOTCH3	Q9UM47-1.2	E890L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	E890M	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	E890N	Pathogenic	0.52
NOTCH3	Q9UM47-1.2	E890P	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	E890Q	Neutral	0.051
NOTCH3	Q9UM47-1.2	E890R	Neutral	0.496
NOTCH3	Q9UM47-1.2	E890S	Neutral	0.499
NOTCH3	Q9UM47-1.2	E890T	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	E890V	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	E890W	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E890Y	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	C891A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C891D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C891E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C891F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C891G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C891H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C891I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C891K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C891L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C891M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C891N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C891P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C891Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C891R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C891S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C891T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C891V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C891W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C891Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	L892A	Neutral	0.125
NOTCH3	Q9UM47-1.2	L892C	Neutral	0.132
NOTCH3	Q9UM47-1.2	L892D	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	L892E	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	L892F	Neutral	0.036
NOTCH3	Q9UM47-1.2	L892G	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	L892H	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	L892I	Neutral	0.002
NOTCH3	Q9UM47-1.2	L892K	Neutral	0.439
NOTCH3	Q9UM47-1.2	L892M	Neutral	0.002
NOTCH3	Q9UM47-1.2	L892N	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	L892P	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	L892Q	Neutral	0.439
NOTCH3	Q9UM47-1.2	L892R	Neutral	0.427
NOTCH3	Q9UM47-1.2	L892S	Neutral	0.4
NOTCH3	Q9UM47-1.2	L892T	Neutral	0.136
NOTCH3	Q9UM47-1.2	L892V	Neutral	0.008
NOTCH3	Q9UM47-1.2	L892W	Neutral	0.409
NOTCH3	Q9UM47-1.2	L892Y	Neutral	0.142
NOTCH3	Q9UM47-1.2	S893A	Neutral	0.11
NOTCH3	Q9UM47-1.2	S893C	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	S893D	Neutral	0.349
NOTCH3	Q9UM47-1.2	S893E	Neutral	0.334
NOTCH3	Q9UM47-1.2	S893F	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	S893G	Neutral	0.342
NOTCH3	Q9UM47-1.2	S893H	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	S893I	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	S893K	Neutral	0.312
NOTCH3	Q9UM47-1.2	S893L	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	S893M	Pathogenic	0.684
NOTCH3	Q9UM47-1.2	S893N	Neutral	0.104
NOTCH3	Q9UM47-1.2	S893P	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	S893Q	Neutral	0.329
NOTCH3	Q9UM47-1.2	S893R	Pathogenic	0.663
NOTCH3	Q9UM47-1.2	S893T	Neutral	0.104
NOTCH3	Q9UM47-1.2	S893V	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	S893W	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	S893Y	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	N894A	Neutral	0.27
NOTCH3	Q9UM47-1.2	N894C	Pathogenic	0.646
NOTCH3	Q9UM47-1.2	N894D	Neutral	0.004
NOTCH3	Q9UM47-1.2	N894E	Neutral	0.019
NOTCH3	Q9UM47-1.2	N894F	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	N894G	Neutral	0.016
NOTCH3	Q9UM47-1.2	N894H	Neutral	0.004
NOTCH3	Q9UM47-1.2	N894I	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	N894K	Neutral	0.017
NOTCH3	Q9UM47-1.2	N894L	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	N894M	Neutral	0.273
NOTCH3	Q9UM47-1.2	N894P	Neutral	0.289
NOTCH3	Q9UM47-1.2	N894Q	Neutral	0.018
NOTCH3	Q9UM47-1.2	N894R	Neutral	0.016
NOTCH3	Q9UM47-1.2	N894S	Neutral	0.004
NOTCH3	Q9UM47-1.2	N894T	Neutral	0.019
NOTCH3	Q9UM47-1.2	N894V	Pathogenic	0.648
NOTCH3	Q9UM47-1.2	N894W	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	N894Y	Neutral	0.26
NOTCH3	Q9UM47-1.2	P895A	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	P895C	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	P895D	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	P895E	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	P895F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P895G	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	P895H	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	P895I	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	P895K	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	P895L	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	P895M	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	P895N	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	P895Q	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	P895R	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	P895S	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	P895T	Pathogenic	0.721
NOTCH3	Q9UM47-1.2	P895V	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	P895W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P895Y	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	C896A	Pathogenic	0.511
NOTCH3	Q9UM47-1.2	C896D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C896E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C896F	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	C896G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C896H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C896I	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C896K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C896L	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C896M	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C896N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C896P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C896Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C896R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C896S	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	C896T	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C896V	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C896W	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	C896Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	G897A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G897C	Neutral	0.155
NOTCH3	Q9UM47-1.2	G897D	Neutral	0.009
NOTCH3	Q9UM47-1.2	G897E	Neutral	0.035
NOTCH3	Q9UM47-1.2	G897F	Neutral	0.132
NOTCH3	Q9UM47-1.2	G897H	Neutral	0.034
NOTCH3	Q9UM47-1.2	G897I	Neutral	0.42
NOTCH3	Q9UM47-1.2	G897K	Neutral	0.032
NOTCH3	Q9UM47-1.2	G897L	Neutral	0.42
NOTCH3	Q9UM47-1.2	G897M	Neutral	0.137
NOTCH3	Q9UM47-1.2	G897N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G897P	Neutral	0.038
NOTCH3	Q9UM47-1.2	G897Q	Neutral	0.035
NOTCH3	Q9UM47-1.2	G897R	Neutral	0.031
NOTCH3	Q9UM47-1.2	G897S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G897T	Neutral	0.037
NOTCH3	Q9UM47-1.2	G897V	Neutral	0.145
NOTCH3	Q9UM47-1.2	G897W	Neutral	0.029
NOTCH3	Q9UM47-1.2	G897Y	Neutral	0.129
NOTCH3	Q9UM47-1.2	P898A	Neutral	0.029
NOTCH3	Q9UM47-1.2	P898C	Neutral	0.402
NOTCH3	Q9UM47-1.2	P898D	Neutral	0.032
NOTCH3	Q9UM47-1.2	P898E	Neutral	0.03
NOTCH3	Q9UM47-1.2	P898F	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	P898G	Neutral	0.113
NOTCH3	Q9UM47-1.2	P898H	Neutral	0.119
NOTCH3	Q9UM47-1.2	P898I	Neutral	0.376
NOTCH3	Q9UM47-1.2	P898K	Neutral	0.027
NOTCH3	Q9UM47-1.2	P898L	Neutral	0.376
NOTCH3	Q9UM47-1.2	P898M	Neutral	0.116
NOTCH3	Q9UM47-1.2	P898N	Neutral	0.129
NOTCH3	Q9UM47-1.2	P898Q	Neutral	0.029
NOTCH3	Q9UM47-1.2	P898R	Neutral	0.108
NOTCH3	Q9UM47-1.2	P898S	Neutral	0.03
NOTCH3	Q9UM47-1.2	P898T	Neutral	0.032
NOTCH3	Q9UM47-1.2	P898V	Neutral	0.124
NOTCH3	Q9UM47-1.2	P898W	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	P898Y	Neutral	0.359
NOTCH3	Q9UM47-1.2	G899A	Neutral	0.24
NOTCH3	Q9UM47-1.2	G899C	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	G899D	Pathogenic	0.568
NOTCH3	Q9UM47-1.2	G899E	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G899F	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G899H	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	G899I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G899K	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G899L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G899M	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G899N	Neutral	0.221
NOTCH3	Q9UM47-1.2	G899P	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	G899Q	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	G899R	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	G899S	Neutral	0.235
NOTCH3	Q9UM47-1.2	G899T	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	G899V	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G899W	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	G899Y	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	T900A	Neutral	0.073
NOTCH3	Q9UM47-1.2	T900C	Neutral	0.28
NOTCH3	Q9UM47-1.2	T900D	Neutral	0.284
NOTCH3	Q9UM47-1.2	T900E	Neutral	0.273
NOTCH3	Q9UM47-1.2	T900F	Pathogenic	0.608
NOTCH3	Q9UM47-1.2	T900G	Pathogenic	0.603
NOTCH3	Q9UM47-1.2	T900H	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	T900I	Neutral	0.263
NOTCH3	Q9UM47-1.2	T900K	Neutral	0.254
NOTCH3	Q9UM47-1.2	T900L	Neutral	0.262
NOTCH3	Q9UM47-1.2	T900M	Neutral	0.262
NOTCH3	Q9UM47-1.2	T900N	Neutral	0.08
NOTCH3	Q9UM47-1.2	T900P	Neutral	0.282
NOTCH3	Q9UM47-1.2	T900Q	Neutral	0.268
NOTCH3	Q9UM47-1.2	T900R	Neutral	0.245
NOTCH3	Q9UM47-1.2	T900S	Neutral	0.017
NOTCH3	Q9UM47-1.2	T900V	Neutral	0.077
NOTCH3	Q9UM47-1.2	T900W	Pathogenic	0.583
NOTCH3	Q9UM47-1.2	T900Y	Pathogenic	0.601
NOTCH3	Q9UM47-1.2	C901A	Pathogenic	0.511
NOTCH3	Q9UM47-1.2	C901D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C901E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C901F	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	C901G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C901H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C901I	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C901K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C901L	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C901M	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C901N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C901P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C901Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C901R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C901S	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	C901T	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C901V	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C901W	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	C901Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	T902A	Neutral	0.098
NOTCH3	Q9UM47-1.2	T902C	Neutral	0.348
NOTCH3	Q9UM47-1.2	T902D	Neutral	0.353
NOTCH3	Q9UM47-1.2	T902E	Neutral	0.34
NOTCH3	Q9UM47-1.2	T902F	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	T902G	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	T902H	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	T902I	Neutral	0.328
NOTCH3	Q9UM47-1.2	T902K	Neutral	0.319
NOTCH3	Q9UM47-1.2	T902L	Neutral	0.328
NOTCH3	Q9UM47-1.2	T902M	Neutral	0.327
NOTCH3	Q9UM47-1.2	T902N	Neutral	0.106
NOTCH3	Q9UM47-1.2	T902P	Neutral	0.351
NOTCH3	Q9UM47-1.2	T902Q	Neutral	0.335
NOTCH3	Q9UM47-1.2	T902R	Neutral	0.308
NOTCH3	Q9UM47-1.2	T902S	Neutral	0.024
NOTCH3	Q9UM47-1.2	T902V	Neutral	0.103
NOTCH3	Q9UM47-1.2	T902W	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	T902Y	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	D903A	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	D903C	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	D903E	Neutral	0.016
NOTCH3	Q9UM47-1.2	D903F	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	D903G	Pathogenic	0.582
NOTCH3	Q9UM47-1.2	D903H	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	D903I	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	D903K	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	D903L	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	D903M	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	D903N	Neutral	0.072
NOTCH3	Q9UM47-1.2	D903P	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	D903Q	Neutral	0.248
NOTCH3	Q9UM47-1.2	D903R	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	D903S	Neutral	0.252
NOTCH3	Q9UM47-1.2	D903T	Pathogenic	0.62
NOTCH3	Q9UM47-1.2	D903V	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	D903W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	D903Y	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	H904A	Neutral	0.356
NOTCH3	Q9UM47-1.2	H904C	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	H904D	Neutral	0.118
NOTCH3	Q9UM47-1.2	H904E	Neutral	0.031
NOTCH3	Q9UM47-1.2	H904F	Neutral	0.123
NOTCH3	Q9UM47-1.2	H904G	Neutral	0.339
NOTCH3	Q9UM47-1.2	H904I	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	H904K	Neutral	0.122
NOTCH3	Q9UM47-1.2	H904L	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	H904M	Neutral	0.398
NOTCH3	Q9UM47-1.2	H904N	Neutral	0.007
NOTCH3	Q9UM47-1.2	H904P	Neutral	0.377
NOTCH3	Q9UM47-1.2	H904Q	Neutral	0.031
NOTCH3	Q9UM47-1.2	H904R	Neutral	0.028
NOTCH3	Q9UM47-1.2	H904S	Neutral	0.11
NOTCH3	Q9UM47-1.2	H904T	Neutral	0.379
NOTCH3	Q9UM47-1.2	H904V	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	H904W	Neutral	0.365
NOTCH3	Q9UM47-1.2	H904Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	V905A	Pathogenic	0.534
NOTCH3	Q9UM47-1.2	V905C	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	V905D	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	V905E	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	V905F	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	V905G	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	V905H	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	V905I	Neutral	0.013
NOTCH3	Q9UM47-1.2	V905K	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	V905L	Neutral	0.213
NOTCH3	Q9UM47-1.2	V905M	Neutral	0.212
NOTCH3	Q9UM47-1.2	V905N	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	V905P	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	V905Q	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	V905R	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	V905S	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	V905T	Pathogenic	0.559
NOTCH3	Q9UM47-1.2	V905W	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	V905Y	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	A906C	Neutral	0.008
NOTCH3	Q9UM47-1.2	A906D	Neutral	0.14
NOTCH3	Q9UM47-1.2	A906E	Neutral	0.032
NOTCH3	Q9UM47-1.2	A906F	Neutral	0.121
NOTCH3	Q9UM47-1.2	A906G	Neutral	0.008
NOTCH3	Q9UM47-1.2	A906H	Neutral	0.127
NOTCH3	Q9UM47-1.2	A906I	Neutral	0.031
NOTCH3	Q9UM47-1.2	A906K	Neutral	0.029
NOTCH3	Q9UM47-1.2	A906L	Neutral	0.031
NOTCH3	Q9UM47-1.2	A906M	Neutral	0.03
NOTCH3	Q9UM47-1.2	A906N	Neutral	0.137
NOTCH3	Q9UM47-1.2	A906P	Neutral	0.034
NOTCH3	Q9UM47-1.2	A906Q	Neutral	0.031
NOTCH3	Q9UM47-1.2	A906R	Neutral	0.028
NOTCH3	Q9UM47-1.2	A906S	Neutral	0.002
NOTCH3	Q9UM47-1.2	A906T	Neutral	0.008
NOTCH3	Q9UM47-1.2	A906V	Neutral	0.007
NOTCH3	Q9UM47-1.2	A906W	Neutral	0.361
NOTCH3	Q9UM47-1.2	A906Y	Neutral	0.118
NOTCH3	Q9UM47-1.2	S907A	Neutral	0.105
NOTCH3	Q9UM47-1.2	S907C	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	S907D	Neutral	0.338
NOTCH3	Q9UM47-1.2	S907E	Neutral	0.322
NOTCH3	Q9UM47-1.2	S907F	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	S907G	Neutral	0.331
NOTCH3	Q9UM47-1.2	S907H	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	S907I	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	S907K	Neutral	0.301
NOTCH3	Q9UM47-1.2	S907L	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	S907M	Pathogenic	0.673
NOTCH3	Q9UM47-1.2	S907N	Neutral	0.099
NOTCH3	Q9UM47-1.2	S907P	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	S907Q	Neutral	0.317
NOTCH3	Q9UM47-1.2	S907R	Pathogenic	0.651
NOTCH3	Q9UM47-1.2	S907T	Neutral	0.1
NOTCH3	Q9UM47-1.2	S907V	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	S907W	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	S907Y	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	F908A	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	F908C	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	F908D	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	F908E	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	F908G	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	F908H	Neutral	0.389
NOTCH3	Q9UM47-1.2	F908I	Neutral	0.124
NOTCH3	Q9UM47-1.2	F908K	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	F908L	Neutral	0.124
NOTCH3	Q9UM47-1.2	F908M	Neutral	0.124
NOTCH3	Q9UM47-1.2	F908N	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	F908P	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	F908Q	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	F908R	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	F908S	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	F908T	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	F908V	Neutral	0.375
NOTCH3	Q9UM47-1.2	F908W	Neutral	0.028
NOTCH3	Q9UM47-1.2	F908Y	Neutral	0.002
NOTCH3	Q9UM47-1.2	T909A	Neutral	0.326
NOTCH3	Q9UM47-1.2	T909C	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	T909D	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	T909E	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	T909F	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	T909G	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	T909H	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	T909I	Pathogenic	0.686
NOTCH3	Q9UM47-1.2	T909K	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	T909L	Pathogenic	0.686
NOTCH3	Q9UM47-1.2	T909M	Pathogenic	0.685
NOTCH3	Q9UM47-1.2	T909N	Neutral	0.347
NOTCH3	Q9UM47-1.2	T909P	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	T909Q	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	T909R	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	T909S	Neutral	0.098
NOTCH3	Q9UM47-1.2	T909V	Neutral	0.34
NOTCH3	Q9UM47-1.2	T909W	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	T909Y	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	C910A	Pathogenic	0.511
NOTCH3	Q9UM47-1.2	C910D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C910E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C910F	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	C910G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C910H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C910I	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C910K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C910L	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C910M	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C910N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C910P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C910Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C910R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C910S	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	C910T	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C910V	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C910W	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	C910Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	T911A	Neutral	0.079
NOTCH3	Q9UM47-1.2	T911C	Neutral	0.297
NOTCH3	Q9UM47-1.2	T911D	Neutral	0.301
NOTCH3	Q9UM47-1.2	T911E	Neutral	0.29
NOTCH3	Q9UM47-1.2	T911F	Pathogenic	0.628
NOTCH3	Q9UM47-1.2	T911G	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	T911H	Pathogenic	0.641
NOTCH3	Q9UM47-1.2	T911I	Neutral	0.279
NOTCH3	Q9UM47-1.2	T911K	Neutral	0.27
NOTCH3	Q9UM47-1.2	T911L	Neutral	0.279
NOTCH3	Q9UM47-1.2	T911M	Neutral	0.278
NOTCH3	Q9UM47-1.2	T911N	Neutral	0.086
NOTCH3	Q9UM47-1.2	T911P	Neutral	0.3
NOTCH3	Q9UM47-1.2	T911Q	Neutral	0.285
NOTCH3	Q9UM47-1.2	T911R	Neutral	0.261
NOTCH3	Q9UM47-1.2	T911S	Neutral	0.019
NOTCH3	Q9UM47-1.2	T911V	Neutral	0.084
NOTCH3	Q9UM47-1.2	T911W	Pathogenic	0.604
NOTCH3	Q9UM47-1.2	T911Y	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	C912A	Pathogenic	0.511
NOTCH3	Q9UM47-1.2	C912D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C912E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C912F	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	C912G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C912H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C912I	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C912K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C912L	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C912M	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C912N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C912P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C912Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C912R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C912S	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	C912T	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C912V	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C912W	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	C912Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	P913A	Neutral	0.236
NOTCH3	Q9UM47-1.2	P913C	Pathogenic	0.873
NOTCH3	Q9UM47-1.2	P913D	Neutral	0.253
NOTCH3	Q9UM47-1.2	P913E	Neutral	0.24
NOTCH3	Q9UM47-1.2	P913F	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	P913G	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	P913H	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	P913I	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	P913K	Neutral	0.223
NOTCH3	Q9UM47-1.2	P913L	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	P913M	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	P913N	Pathogenic	0.602
NOTCH3	Q9UM47-1.2	P913Q	Neutral	0.236
NOTCH3	Q9UM47-1.2	P913R	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	P913S	Neutral	0.24
NOTCH3	Q9UM47-1.2	P913T	Neutral	0.25
NOTCH3	Q9UM47-1.2	P913V	Pathogenic	0.592
NOTCH3	Q9UM47-1.2	P913W	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	P913Y	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	P914A	Neutral	0.095
NOTCH3	Q9UM47-1.2	P914C	Pathogenic	0.701
NOTCH3	Q9UM47-1.2	P914D	Neutral	0.103
NOTCH3	Q9UM47-1.2	P914E	Neutral	0.097
NOTCH3	Q9UM47-1.2	P914F	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	P914G	Neutral	0.308
NOTCH3	Q9UM47-1.2	P914H	Neutral	0.32
NOTCH3	Q9UM47-1.2	P914I	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	P914K	Neutral	0.089
NOTCH3	Q9UM47-1.2	P914L	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	P914M	Neutral	0.315
NOTCH3	Q9UM47-1.2	P914N	Neutral	0.34
NOTCH3	Q9UM47-1.2	P914Q	Neutral	0.095
NOTCH3	Q9UM47-1.2	P914R	Neutral	0.297
NOTCH3	Q9UM47-1.2	P914S	Neutral	0.097
NOTCH3	Q9UM47-1.2	P914T	Neutral	0.102
NOTCH3	Q9UM47-1.2	P914V	Neutral	0.331
NOTCH3	Q9UM47-1.2	P914W	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	P914Y	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	G915A	Neutral	0.245
NOTCH3	Q9UM47-1.2	G915C	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	G915D	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	G915E	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	G915F	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G915H	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	G915I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G915K	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	G915L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G915M	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G915N	Neutral	0.225
NOTCH3	Q9UM47-1.2	G915P	Pathogenic	0.861
NOTCH3	Q9UM47-1.2	G915Q	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	G915R	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	G915S	Neutral	0.24
NOTCH3	Q9UM47-1.2	G915T	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	G915V	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G915W	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	G915Y	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	Y916A	Pathogenic	0.588
NOTCH3	Q9UM47-1.2	Y916C	Pathogenic	0.604
NOTCH3	Q9UM47-1.2	Y916D	Pathogenic	0.878
NOTCH3	Q9UM47-1.2	Y916E	Pathogenic	0.628
NOTCH3	Q9UM47-1.2	Y916F	Neutral	0.001
NOTCH3	Q9UM47-1.2	Y916G	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	Y916H	Neutral	0.004
NOTCH3	Q9UM47-1.2	Y916I	Neutral	0.281
NOTCH3	Q9UM47-1.2	Y916K	Pathogenic	0.652
NOTCH3	Q9UM47-1.2	Y916L	Neutral	0.281
NOTCH3	Q9UM47-1.2	Y916M	Neutral	0.28
NOTCH3	Q9UM47-1.2	Y916N	Pathogenic	0.617
NOTCH3	Q9UM47-1.2	Y916P	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	Y916Q	Neutral	0.274
NOTCH3	Q9UM47-1.2	Y916R	Pathogenic	0.651
NOTCH3	Q9UM47-1.2	Y916S	Pathogenic	0.594
NOTCH3	Q9UM47-1.2	Y916T	Pathogenic	0.612
NOTCH3	Q9UM47-1.2	Y916V	Neutral	0.266
NOTCH3	Q9UM47-1.2	Y916W	Neutral	0.004
NOTCH3	Q9UM47-1.2	G917A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G917C	Neutral	0.135
NOTCH3	Q9UM47-1.2	G917D	Neutral	0.007
NOTCH3	Q9UM47-1.2	G917E	Neutral	0.03
NOTCH3	Q9UM47-1.2	G917F	Neutral	0.115
NOTCH3	Q9UM47-1.2	G917H	Neutral	0.029
NOTCH3	Q9UM47-1.2	G917I	Neutral	0.381
NOTCH3	Q9UM47-1.2	G917K	Neutral	0.028
NOTCH3	Q9UM47-1.2	G917L	Neutral	0.381
NOTCH3	Q9UM47-1.2	G917M	Neutral	0.119
NOTCH3	Q9UM47-1.2	G917N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G917P	Neutral	0.033
NOTCH3	Q9UM47-1.2	G917Q	Neutral	0.03
NOTCH3	Q9UM47-1.2	G917R	Neutral	0.026
NOTCH3	Q9UM47-1.2	G917S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G917T	Neutral	0.032
NOTCH3	Q9UM47-1.2	G917V	Neutral	0.127
NOTCH3	Q9UM47-1.2	G917W	Neutral	0.025
NOTCH3	Q9UM47-1.2	G917Y	Neutral	0.112
NOTCH3	Q9UM47-1.2	G918A	Neutral	0.232
NOTCH3	Q9UM47-1.2	G918C	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G918D	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	G918E	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	G918F	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G918H	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G918I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G918K	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G918L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G918M	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G918N	Neutral	0.213
NOTCH3	Q9UM47-1.2	G918P	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	G918Q	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	G918R	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	G918S	Neutral	0.228
NOTCH3	Q9UM47-1.2	G918T	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	G918V	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G918W	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	G918Y	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	F919A	Neutral	0.283
NOTCH3	Q9UM47-1.2	F919C	Neutral	0.297
NOTCH3	Q9UM47-1.2	F919D	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	F919E	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	F919G	Pathogenic	0.626
NOTCH3	Q9UM47-1.2	F919H	Neutral	0.095
NOTCH3	Q9UM47-1.2	F919I	Neutral	0.023
NOTCH3	Q9UM47-1.2	F919K	Pathogenic	0.702
NOTCH3	Q9UM47-1.2	F919L	Neutral	0.023
NOTCH3	Q9UM47-1.2	F919M	Neutral	0.023
NOTCH3	Q9UM47-1.2	F919N	Pathogenic	0.669
NOTCH3	Q9UM47-1.2	F919P	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	F919Q	Pathogenic	0.684
NOTCH3	Q9UM47-1.2	F919R	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	F919S	Neutral	0.288
NOTCH3	Q9UM47-1.2	F919T	Neutral	0.304
NOTCH3	Q9UM47-1.2	F919V	Neutral	0.091
NOTCH3	Q9UM47-1.2	F919W	Neutral	0.005
NOTCH3	Q9UM47-1.2	F919Y	Neutral	0.0
NOTCH3	Q9UM47-1.2	H920A	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	H920C	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	H920D	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	H920E	Neutral	0.329
NOTCH3	Q9UM47-1.2	H920F	Pathogenic	0.686
NOTCH3	Q9UM47-1.2	H920G	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	H920I	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	H920K	Pathogenic	0.685
NOTCH3	Q9UM47-1.2	H920L	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	H920M	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	H920N	Neutral	0.093
NOTCH3	Q9UM47-1.2	H920P	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	H920Q	Neutral	0.333
NOTCH3	Q9UM47-1.2	H920R	Neutral	0.312
NOTCH3	Q9UM47-1.2	H920S	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	H920T	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	H920V	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	H920W	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	H920Y	Neutral	0.022
NOTCH3	Q9UM47-1.2	C921A	Pathogenic	0.507
NOTCH3	Q9UM47-1.2	C921D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C921E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C921F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	C921G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C921H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C921I	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C921K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C921L	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C921M	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	C921N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C921P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C921Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C921R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C921S	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	C921T	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	C921V	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C921W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C921Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	E922A	Pathogenic	0.655
NOTCH3	Q9UM47-1.2	E922C	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	E922D	Neutral	0.021
NOTCH3	Q9UM47-1.2	E922F	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	E922G	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	E922H	Neutral	0.321
NOTCH3	Q9UM47-1.2	E922I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	E922K	Neutral	0.088
NOTCH3	Q9UM47-1.2	E922L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	E922M	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	E922N	Neutral	0.316
NOTCH3	Q9UM47-1.2	E922P	Pathogenic	0.675
NOTCH3	Q9UM47-1.2	E922Q	Neutral	0.023
NOTCH3	Q9UM47-1.2	E922R	Neutral	0.296
NOTCH3	Q9UM47-1.2	E922S	Neutral	0.298
NOTCH3	Q9UM47-1.2	E922T	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	E922V	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	E922W	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	E922Y	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	Q923A	Neutral	0.013
NOTCH3	Q9UM47-1.2	Q923C	Neutral	0.232
NOTCH3	Q9UM47-1.2	Q923D	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q923E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q923F	Neutral	0.238
NOTCH3	Q9UM47-1.2	Q923G	Neutral	0.054
NOTCH3	Q9UM47-1.2	Q923H	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q923I	Neutral	0.246
NOTCH3	Q9UM47-1.2	Q923K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q923L	Neutral	0.067
NOTCH3	Q9UM47-1.2	Q923M	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q923N	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q923P	Neutral	0.015
NOTCH3	Q9UM47-1.2	Q923R	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q923S	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q923T	Neutral	0.015
NOTCH3	Q9UM47-1.2	Q923V	Neutral	0.067
NOTCH3	Q9UM47-1.2	Q923W	Neutral	0.058
NOTCH3	Q9UM47-1.2	Q923Y	Neutral	0.014
NOTCH3	Q9UM47-1.2	D924A	Neutral	0.259
NOTCH3	Q9UM47-1.2	D924C	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	D924E	Neutral	0.001
NOTCH3	Q9UM47-1.2	D924F	Pathogenic	0.598
NOTCH3	Q9UM47-1.2	D924G	Neutral	0.066
NOTCH3	Q9UM47-1.2	D924H	Neutral	0.07
NOTCH3	Q9UM47-1.2	D924I	Pathogenic	0.609
NOTCH3	Q9UM47-1.2	D924K	Neutral	0.066
NOTCH3	Q9UM47-1.2	D924L	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	D924M	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	D924N	Neutral	0.004
NOTCH3	Q9UM47-1.2	D924P	Neutral	0.078
NOTCH3	Q9UM47-1.2	D924Q	Neutral	0.017
NOTCH3	Q9UM47-1.2	D924R	Neutral	0.234
NOTCH3	Q9UM47-1.2	D924S	Neutral	0.017
NOTCH3	Q9UM47-1.2	D924T	Neutral	0.077
NOTCH3	Q9UM47-1.2	D924V	Pathogenic	0.625
NOTCH3	Q9UM47-1.2	D924W	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	D924Y	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	L925A	Neutral	0.016
NOTCH3	Q9UM47-1.2	L925C	Neutral	0.018
NOTCH3	Q9UM47-1.2	L925D	Pathogenic	0.635
NOTCH3	Q9UM47-1.2	L925E	Neutral	0.29
NOTCH3	Q9UM47-1.2	L925F	Neutral	0.004
NOTCH3	Q9UM47-1.2	L925G	Pathogenic	0.594
NOTCH3	Q9UM47-1.2	L925H	Neutral	0.296
NOTCH3	Q9UM47-1.2	L925I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L925K	Neutral	0.084
NOTCH3	Q9UM47-1.2	L925M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L925N	Neutral	0.28
NOTCH3	Q9UM47-1.2	L925P	Neutral	0.273
NOTCH3	Q9UM47-1.2	L925Q	Neutral	0.084
NOTCH3	Q9UM47-1.2	L925R	Neutral	0.08
NOTCH3	Q9UM47-1.2	L925S	Neutral	0.072
NOTCH3	Q9UM47-1.2	L925T	Neutral	0.018
NOTCH3	Q9UM47-1.2	L925V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L925W	Neutral	0.075
NOTCH3	Q9UM47-1.2	L925Y	Neutral	0.019
NOTCH3	Q9UM47-1.2	P926A	Neutral	0.155
NOTCH3	Q9UM47-1.2	P926C	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	P926D	Neutral	0.168
NOTCH3	Q9UM47-1.2	P926E	Neutral	0.158
NOTCH3	Q9UM47-1.2	P926F	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	P926G	Neutral	0.438
NOTCH3	Q9UM47-1.2	P926H	Neutral	0.451
NOTCH3	Q9UM47-1.2	P926I	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	P926K	Neutral	0.146
NOTCH3	Q9UM47-1.2	P926L	Pathogenic	0.785
NOTCH3	Q9UM47-1.2	P926M	Neutral	0.445
NOTCH3	Q9UM47-1.2	P926N	Neutral	0.473
NOTCH3	Q9UM47-1.2	P926Q	Neutral	0.155
NOTCH3	Q9UM47-1.2	P926R	Neutral	0.425
NOTCH3	Q9UM47-1.2	P926S	Neutral	0.158
NOTCH3	Q9UM47-1.2	P926T	Neutral	0.165
NOTCH3	Q9UM47-1.2	P926V	Neutral	0.463
NOTCH3	Q9UM47-1.2	P926W	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	P926Y	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	D927A	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	D927C	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	D927E	Neutral	0.008
NOTCH3	Q9UM47-1.2	D927F	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	D927G	Neutral	0.407
NOTCH3	Q9UM47-1.2	D927H	Neutral	0.422
NOTCH3	Q9UM47-1.2	D927I	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	D927K	Neutral	0.405
NOTCH3	Q9UM47-1.2	D927L	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D927M	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	D927N	Neutral	0.037
NOTCH3	Q9UM47-1.2	D927P	Neutral	0.448
NOTCH3	Q9UM47-1.2	D927Q	Neutral	0.14
NOTCH3	Q9UM47-1.2	D927R	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	D927S	Neutral	0.142
NOTCH3	Q9UM47-1.2	D927T	Neutral	0.446
NOTCH3	Q9UM47-1.2	D927V	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	D927W	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D927Y	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	C928A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C928D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C928E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C928F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C928G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C928H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C928I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C928K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C928L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C928M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C928N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C928P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C928Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C928R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C928S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C928T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C928V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C928W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C928Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	S929A	Neutral	0.003
NOTCH3	Q9UM47-1.2	S929C	Neutral	0.055
NOTCH3	Q9UM47-1.2	S929D	Neutral	0.012
NOTCH3	Q9UM47-1.2	S929E	Neutral	0.011
NOTCH3	Q9UM47-1.2	S929F	Neutral	0.18
NOTCH3	Q9UM47-1.2	S929G	Neutral	0.012
NOTCH3	Q9UM47-1.2	S929H	Neutral	0.048
NOTCH3	Q9UM47-1.2	S929I	Neutral	0.187
NOTCH3	Q9UM47-1.2	S929K	Neutral	0.01
NOTCH3	Q9UM47-1.2	S929L	Neutral	0.186
NOTCH3	Q9UM47-1.2	S929M	Neutral	0.048
NOTCH3	Q9UM47-1.2	S929N	Neutral	0.003
NOTCH3	Q9UM47-1.2	S929P	Neutral	0.054
NOTCH3	Q9UM47-1.2	S929Q	Neutral	0.011
NOTCH3	Q9UM47-1.2	S929R	Neutral	0.044
NOTCH3	Q9UM47-1.2	S929T	Neutral	0.003
NOTCH3	Q9UM47-1.2	S929V	Neutral	0.197
NOTCH3	Q9UM47-1.2	S929W	Neutral	0.474
NOTCH3	Q9UM47-1.2	S929Y	Neutral	0.176
NOTCH3	Q9UM47-1.2	P930A	Neutral	0.024
NOTCH3	Q9UM47-1.2	P930C	Neutral	0.356
NOTCH3	Q9UM47-1.2	P930D	Neutral	0.027
NOTCH3	Q9UM47-1.2	P930E	Neutral	0.025
NOTCH3	Q9UM47-1.2	P930F	Pathogenic	0.684
NOTCH3	Q9UM47-1.2	P930G	Neutral	0.095
NOTCH3	Q9UM47-1.2	P930H	Neutral	0.1
NOTCH3	Q9UM47-1.2	P930I	Neutral	0.332
NOTCH3	Q9UM47-1.2	P930K	Neutral	0.023
NOTCH3	Q9UM47-1.2	P930L	Neutral	0.332
NOTCH3	Q9UM47-1.2	P930M	Neutral	0.098
NOTCH3	Q9UM47-1.2	P930N	Neutral	0.109
NOTCH3	Q9UM47-1.2	P930Q	Neutral	0.024
NOTCH3	Q9UM47-1.2	P930R	Neutral	0.091
NOTCH3	Q9UM47-1.2	P930S	Neutral	0.025
NOTCH3	Q9UM47-1.2	P930T	Neutral	0.026
NOTCH3	Q9UM47-1.2	P930V	Neutral	0.105
NOTCH3	Q9UM47-1.2	P930W	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	P930Y	Neutral	0.316
NOTCH3	Q9UM47-1.2	S931A	Neutral	0.101
NOTCH3	Q9UM47-1.2	S931C	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	S931D	Neutral	0.329
NOTCH3	Q9UM47-1.2	S931E	Neutral	0.314
NOTCH3	Q9UM47-1.2	S931F	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	S931G	Neutral	0.322
NOTCH3	Q9UM47-1.2	S931H	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	S931I	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	S931K	Neutral	0.293
NOTCH3	Q9UM47-1.2	S931L	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	S931M	Pathogenic	0.664
NOTCH3	Q9UM47-1.2	S931N	Neutral	0.096
NOTCH3	Q9UM47-1.2	S931P	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	S931Q	Neutral	0.309
NOTCH3	Q9UM47-1.2	S931R	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	S931T	Neutral	0.096
NOTCH3	Q9UM47-1.2	S931V	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	S931W	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	S931Y	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	S932A	Neutral	0.111
NOTCH3	Q9UM47-1.2	S932C	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	S932D	Neutral	0.353
NOTCH3	Q9UM47-1.2	S932E	Neutral	0.338
NOTCH3	Q9UM47-1.2	S932F	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	S932G	Neutral	0.346
NOTCH3	Q9UM47-1.2	S932H	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	S932I	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	S932K	Neutral	0.316
NOTCH3	Q9UM47-1.2	S932L	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	S932M	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	S932N	Neutral	0.105
NOTCH3	Q9UM47-1.2	S932P	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	S932Q	Neutral	0.332
NOTCH3	Q9UM47-1.2	S932R	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	S932T	Neutral	0.106
NOTCH3	Q9UM47-1.2	S932V	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	S932W	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	S932Y	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	C933A	Pathogenic	0.509
NOTCH3	Q9UM47-1.2	C933D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C933E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C933F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	C933G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C933H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C933I	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C933K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C933L	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C933M	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C933N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C933P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C933Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C933R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C933S	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C933T	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	C933V	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C933W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C933Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	F934A	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	F934C	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	F934D	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	F934E	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	F934G	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	F934H	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	F934I	Pathogenic	0.608
NOTCH3	Q9UM47-1.2	F934K	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	F934L	Pathogenic	0.608
NOTCH3	Q9UM47-1.2	F934M	Pathogenic	0.609
NOTCH3	Q9UM47-1.2	F934N	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	F934P	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	F934Q	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	F934R	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	F934S	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	F934T	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	F934V	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	F934W	Neutral	0.243
NOTCH3	Q9UM47-1.2	F934Y	Neutral	0.017
NOTCH3	Q9UM47-1.2	N935A	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	N935C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N935D	Neutral	0.135
NOTCH3	Q9UM47-1.2	N935E	Neutral	0.407
NOTCH3	Q9UM47-1.2	N935F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N935G	Neutral	0.376
NOTCH3	Q9UM47-1.2	N935H	Neutral	0.128
NOTCH3	Q9UM47-1.2	N935I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N935K	Neutral	0.384
NOTCH3	Q9UM47-1.2	N935L	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N935M	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	N935P	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	N935Q	Neutral	0.403
NOTCH3	Q9UM47-1.2	N935R	Neutral	0.372
NOTCH3	Q9UM47-1.2	N935S	Neutral	0.127
NOTCH3	Q9UM47-1.2	N935T	Neutral	0.418
NOTCH3	Q9UM47-1.2	N935V	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N935W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N935Y	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	G936A	Neutral	0.156
NOTCH3	Q9UM47-1.2	G936C	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	G936D	Neutral	0.435
NOTCH3	Q9UM47-1.2	G936E	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	G936F	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	G936H	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	G936I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	G936K	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	G936L	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	G936M	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	G936N	Neutral	0.142
NOTCH3	Q9UM47-1.2	G936P	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	G936Q	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	G936R	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	G936S	Neutral	0.153
NOTCH3	Q9UM47-1.2	G936T	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	G936V	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	G936W	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	G936Y	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	G937A	Neutral	0.225
NOTCH3	Q9UM47-1.2	G937C	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	G937D	Pathogenic	0.547
NOTCH3	Q9UM47-1.2	G937E	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G937F	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G937H	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	G937I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G937K	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	G937L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G937M	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G937N	Neutral	0.206
NOTCH3	Q9UM47-1.2	G937P	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	G937Q	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	G937R	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	G937S	Neutral	0.221
NOTCH3	Q9UM47-1.2	G937T	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	G937V	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G937W	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	G937Y	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	T938A	Neutral	0.382
NOTCH3	Q9UM47-1.2	T938C	Pathogenic	0.753
NOTCH3	Q9UM47-1.2	T938D	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	T938E	Pathogenic	0.747
NOTCH3	Q9UM47-1.2	T938F	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	T938G	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	T938H	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	T938I	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	T938K	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	T938L	Pathogenic	0.736
NOTCH3	Q9UM47-1.2	T938M	Pathogenic	0.736
NOTCH3	Q9UM47-1.2	T938N	Neutral	0.405
NOTCH3	Q9UM47-1.2	T938P	Pathogenic	0.755
NOTCH3	Q9UM47-1.2	T938Q	Pathogenic	0.742
NOTCH3	Q9UM47-1.2	T938R	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	T938S	Neutral	0.122
NOTCH3	Q9UM47-1.2	T938V	Neutral	0.397
NOTCH3	Q9UM47-1.2	T938W	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	T938Y	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	C939A	Neutral	0.495
NOTCH3	Q9UM47-1.2	C939D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C939E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C939F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	C939G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C939H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C939I	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	C939K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C939L	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	C939M	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C939N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C939P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C939Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C939R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C939S	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	C939T	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	C939V	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C939W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C939Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	V940A	Neutral	0.203
NOTCH3	Q9UM47-1.2	V940C	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	V940D	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	V940E	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	V940F	Pathogenic	0.544
NOTCH3	Q9UM47-1.2	V940G	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	V940H	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	V940I	Neutral	0.003
NOTCH3	Q9UM47-1.2	V940K	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	V940L	Neutral	0.057
NOTCH3	Q9UM47-1.2	V940M	Neutral	0.056
NOTCH3	Q9UM47-1.2	V940N	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	V940P	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	V940Q	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	V940R	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	V940S	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	V940T	Neutral	0.22
NOTCH3	Q9UM47-1.2	V940W	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	V940Y	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	D941A	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	D941C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D941E	Neutral	0.033
NOTCH3	Q9UM47-1.2	D941F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D941G	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	D941H	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	D941I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D941K	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	D941L	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	D941M	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D941N	Neutral	0.141
NOTCH3	Q9UM47-1.2	D941P	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	D941Q	Neutral	0.412
NOTCH3	Q9UM47-1.2	D941R	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	D941S	Neutral	0.417
NOTCH3	Q9UM47-1.2	D941T	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	D941V	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D941W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D941Y	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	G942A	Neutral	0.123
NOTCH3	Q9UM47-1.2	G942C	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	G942D	Neutral	0.368
NOTCH3	Q9UM47-1.2	G942E	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	G942F	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	G942H	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	G942I	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	G942K	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	G942L	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	G942M	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	G942N	Neutral	0.111
NOTCH3	Q9UM47-1.2	G942P	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	G942Q	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	G942R	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	G942S	Neutral	0.12
NOTCH3	Q9UM47-1.2	G942T	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	G942V	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	G942W	Pathogenic	0.67
NOTCH3	Q9UM47-1.2	G942Y	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	V943A	Neutral	0.032
NOTCH3	Q9UM47-1.2	V943C	Neutral	0.139
NOTCH3	Q9UM47-1.2	V943D	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	V943E	Neutral	0.44
NOTCH3	Q9UM47-1.2	V943F	Neutral	0.134
NOTCH3	Q9UM47-1.2	V943G	Pathogenic	0.744
NOTCH3	Q9UM47-1.2	V943H	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	V943I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V943K	Neutral	0.416
NOTCH3	Q9UM47-1.2	V943L	Neutral	0.008
NOTCH3	Q9UM47-1.2	V943M	Neutral	0.008
NOTCH3	Q9UM47-1.2	V943N	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	V943P	Neutral	0.427
NOTCH3	Q9UM47-1.2	V943Q	Neutral	0.435
NOTCH3	Q9UM47-1.2	V943R	Pathogenic	0.756
NOTCH3	Q9UM47-1.2	V943S	Neutral	0.413
NOTCH3	Q9UM47-1.2	V943T	Neutral	0.035
NOTCH3	Q9UM47-1.2	V943W	Pathogenic	0.743
NOTCH3	Q9UM47-1.2	V943Y	Neutral	0.131
NOTCH3	Q9UM47-1.2	N944A	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	N944C	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N944D	Neutral	0.126
NOTCH3	Q9UM47-1.2	N944E	Neutral	0.389
NOTCH3	Q9UM47-1.2	N944F	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	N944G	Neutral	0.359
NOTCH3	Q9UM47-1.2	N944H	Neutral	0.12
NOTCH3	Q9UM47-1.2	N944I	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	N944K	Neutral	0.366
NOTCH3	Q9UM47-1.2	N944L	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	N944M	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	N944P	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	N944Q	Neutral	0.385
NOTCH3	Q9UM47-1.2	N944R	Neutral	0.355
NOTCH3	Q9UM47-1.2	N944S	Neutral	0.119
NOTCH3	Q9UM47-1.2	N944T	Neutral	0.4
NOTCH3	Q9UM47-1.2	N944V	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N944W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N944Y	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	S945A	Neutral	0.016
NOTCH3	Q9UM47-1.2	S945C	Neutral	0.246
NOTCH3	Q9UM47-1.2	S945D	Neutral	0.066
NOTCH3	Q9UM47-1.2	S945E	Neutral	0.061
NOTCH3	Q9UM47-1.2	S945F	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	S945G	Neutral	0.064
NOTCH3	Q9UM47-1.2	S945H	Neutral	0.223
NOTCH3	Q9UM47-1.2	S945I	Pathogenic	0.564
NOTCH3	Q9UM47-1.2	S945K	Neutral	0.056
NOTCH3	Q9UM47-1.2	S945L	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	S945M	Neutral	0.22
NOTCH3	Q9UM47-1.2	S945N	Neutral	0.015
NOTCH3	Q9UM47-1.2	S945P	Neutral	0.243
NOTCH3	Q9UM47-1.2	S945Q	Neutral	0.06
NOTCH3	Q9UM47-1.2	S945R	Neutral	0.204
NOTCH3	Q9UM47-1.2	S945T	Neutral	0.015
NOTCH3	Q9UM47-1.2	S945V	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	S945W	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	S945Y	Pathogenic	0.546
NOTCH3	Q9UM47-1.2	F946A	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	F946C	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	F946D	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	F946E	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	F946G	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	F946H	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	F946I	Pathogenic	0.65
NOTCH3	Q9UM47-1.2	F946K	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	F946L	Pathogenic	0.65
NOTCH3	Q9UM47-1.2	F946M	Pathogenic	0.651
NOTCH3	Q9UM47-1.2	F946N	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	F946P	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	F946Q	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	F946R	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	F946S	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	F946T	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	F946V	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	F946W	Neutral	0.277
NOTCH3	Q9UM47-1.2	F946Y	Neutral	0.02
NOTCH3	Q9UM47-1.2	S947A	Neutral	0.009
NOTCH3	Q9UM47-1.2	S947C	Neutral	0.158
NOTCH3	Q9UM47-1.2	S947D	Neutral	0.039
NOTCH3	Q9UM47-1.2	S947E	Neutral	0.036
NOTCH3	Q9UM47-1.2	S947F	Neutral	0.417
NOTCH3	Q9UM47-1.2	S947G	Neutral	0.038
NOTCH3	Q9UM47-1.2	S947H	Neutral	0.142
NOTCH3	Q9UM47-1.2	S947I	Neutral	0.427
NOTCH3	Q9UM47-1.2	S947K	Neutral	0.033
NOTCH3	Q9UM47-1.2	S947L	Neutral	0.427
NOTCH3	Q9UM47-1.2	S947M	Neutral	0.14
NOTCH3	Q9UM47-1.2	S947N	Neutral	0.009
NOTCH3	Q9UM47-1.2	S947P	Neutral	0.156
NOTCH3	Q9UM47-1.2	S947Q	Neutral	0.036
NOTCH3	Q9UM47-1.2	S947R	Neutral	0.129
NOTCH3	Q9UM47-1.2	S947T	Neutral	0.009
NOTCH3	Q9UM47-1.2	S947V	Neutral	0.444
NOTCH3	Q9UM47-1.2	S947W	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	S947Y	Neutral	0.409
NOTCH3	Q9UM47-1.2	C948A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C948D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C948E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C948F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C948G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C948H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C948I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C948K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C948L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C948M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C948N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C948P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C948Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C948R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C948S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C948T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C948V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C948W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C948Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	L949A	Neutral	0.192
NOTCH3	Q9UM47-1.2	L949C	Neutral	0.203
NOTCH3	Q9UM47-1.2	L949D	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	L949E	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	L949F	Neutral	0.058
NOTCH3	Q9UM47-1.2	L949G	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	L949H	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	L949I	Neutral	0.003
NOTCH3	Q9UM47-1.2	L949K	Pathogenic	0.566
NOTCH3	Q9UM47-1.2	L949M	Neutral	0.003
NOTCH3	Q9UM47-1.2	L949N	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	L949P	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	L949Q	Pathogenic	0.566
NOTCH3	Q9UM47-1.2	L949R	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	L949S	Pathogenic	0.526
NOTCH3	Q9UM47-1.2	L949T	Neutral	0.208
NOTCH3	Q9UM47-1.2	L949V	Neutral	0.013
NOTCH3	Q9UM47-1.2	L949W	Pathogenic	0.535
NOTCH3	Q9UM47-1.2	L949Y	Neutral	0.216
NOTCH3	Q9UM47-1.2	C950A	Neutral	0.492
NOTCH3	Q9UM47-1.2	C950D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C950E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C950F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C950G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C950H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C950I	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C950K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C950L	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C950M	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C950N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C950P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C950Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C950R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C950S	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C950T	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C950V	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C950W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C950Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	R951A	Neutral	0.114
NOTCH3	Q9UM47-1.2	R951C	Pathogenic	0.743
NOTCH3	Q9UM47-1.2	R951D	Neutral	0.39
NOTCH3	Q9UM47-1.2	R951E	Neutral	0.032
NOTCH3	Q9UM47-1.2	R951F	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	R951G	Neutral	0.353
NOTCH3	Q9UM47-1.2	R951H	Neutral	0.033
NOTCH3	Q9UM47-1.2	R951I	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	R951K	Neutral	0.002
NOTCH3	Q9UM47-1.2	R951L	Neutral	0.425
NOTCH3	Q9UM47-1.2	R951M	Neutral	0.139
NOTCH3	Q9UM47-1.2	R951N	Neutral	0.03
NOTCH3	Q9UM47-1.2	R951P	Neutral	0.392
NOTCH3	Q9UM47-1.2	R951Q	Neutral	0.007
NOTCH3	Q9UM47-1.2	R951S	Neutral	0.116
NOTCH3	Q9UM47-1.2	R951T	Neutral	0.125
NOTCH3	Q9UM47-1.2	R951V	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	R951W	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	R951Y	Neutral	0.44
NOTCH3	Q9UM47-1.2	P952A	Neutral	0.166
NOTCH3	Q9UM47-1.2	P952C	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	P952D	Neutral	0.179
NOTCH3	Q9UM47-1.2	P952E	Neutral	0.169
NOTCH3	Q9UM47-1.2	P952F	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	P952G	Neutral	0.458
NOTCH3	Q9UM47-1.2	P952H	Neutral	0.471
NOTCH3	Q9UM47-1.2	P952I	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	P952K	Neutral	0.156
NOTCH3	Q9UM47-1.2	P952L	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	P952M	Neutral	0.465
NOTCH3	Q9UM47-1.2	P952N	Neutral	0.494
NOTCH3	Q9UM47-1.2	P952Q	Neutral	0.166
NOTCH3	Q9UM47-1.2	P952R	Neutral	0.445
NOTCH3	Q9UM47-1.2	P952S	Neutral	0.17
NOTCH3	Q9UM47-1.2	P952T	Neutral	0.177
NOTCH3	Q9UM47-1.2	P952V	Neutral	0.483
NOTCH3	Q9UM47-1.2	P952W	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	P952Y	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	G953A	Neutral	0.222
NOTCH3	Q9UM47-1.2	G953C	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	G953D	Pathogenic	0.544
NOTCH3	Q9UM47-1.2	G953E	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G953F	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G953H	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G953I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G953K	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	G953L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G953M	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G953N	Neutral	0.204
NOTCH3	Q9UM47-1.2	G953P	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	G953Q	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	G953R	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	G953S	Neutral	0.218
NOTCH3	Q9UM47-1.2	G953T	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	G953V	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G953W	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	G953Y	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	Y954A	Pathogenic	0.628
NOTCH3	Q9UM47-1.2	Y954C	Pathogenic	0.643
NOTCH3	Q9UM47-1.2	Y954D	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	Y954E	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	Y954F	Neutral	0.001
NOTCH3	Q9UM47-1.2	Y954G	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	Y954H	Neutral	0.005
NOTCH3	Q9UM47-1.2	Y954I	Neutral	0.316
NOTCH3	Q9UM47-1.2	Y954K	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	Y954L	Neutral	0.316
NOTCH3	Q9UM47-1.2	Y954M	Neutral	0.315
NOTCH3	Q9UM47-1.2	Y954N	Pathogenic	0.655
NOTCH3	Q9UM47-1.2	Y954P	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	Y954Q	Neutral	0.308
NOTCH3	Q9UM47-1.2	Y954R	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	Y954S	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	Y954T	Pathogenic	0.651
NOTCH3	Q9UM47-1.2	Y954V	Neutral	0.299
NOTCH3	Q9UM47-1.2	Y954W	Neutral	0.005
NOTCH3	Q9UM47-1.2	T955A	Neutral	0.302
NOTCH3	Q9UM47-1.2	T955C	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	T955D	Pathogenic	0.685
NOTCH3	Q9UM47-1.2	T955E	Pathogenic	0.673
NOTCH3	Q9UM47-1.2	T955F	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	T955G	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	T955H	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	T955I	Pathogenic	0.662
NOTCH3	Q9UM47-1.2	T955K	Pathogenic	0.652
NOTCH3	Q9UM47-1.2	T955L	Pathogenic	0.662
NOTCH3	Q9UM47-1.2	T955M	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	T955N	Neutral	0.323
NOTCH3	Q9UM47-1.2	T955P	Pathogenic	0.684
NOTCH3	Q9UM47-1.2	T955Q	Pathogenic	0.668
NOTCH3	Q9UM47-1.2	T955R	Pathogenic	0.64
NOTCH3	Q9UM47-1.2	T955S	Neutral	0.089
NOTCH3	Q9UM47-1.2	T955V	Neutral	0.315
NOTCH3	Q9UM47-1.2	T955W	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	T955Y	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	G956A	Neutral	0.243
NOTCH3	Q9UM47-1.2	G956C	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	G956D	Pathogenic	0.572
NOTCH3	Q9UM47-1.2	G956E	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	G956F	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G956H	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	G956I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G956K	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G956L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G956M	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G956N	Neutral	0.223
NOTCH3	Q9UM47-1.2	G956P	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	G956Q	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	G956R	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	G956S	Neutral	0.238
NOTCH3	Q9UM47-1.2	G956T	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	G956V	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G956W	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	G956Y	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	A957C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A957D	Neutral	0.049
NOTCH3	Q9UM47-1.2	A957E	Neutral	0.01
NOTCH3	Q9UM47-1.2	A957F	Neutral	0.042
NOTCH3	Q9UM47-1.2	A957G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A957H	Neutral	0.044
NOTCH3	Q9UM47-1.2	A957I	Neutral	0.01
NOTCH3	Q9UM47-1.2	A957K	Neutral	0.01
NOTCH3	Q9UM47-1.2	A957L	Neutral	0.01
NOTCH3	Q9UM47-1.2	A957M	Neutral	0.01
NOTCH3	Q9UM47-1.2	A957N	Neutral	0.048
NOTCH3	Q9UM47-1.2	A957P	Neutral	0.011
NOTCH3	Q9UM47-1.2	A957Q	Neutral	0.01
NOTCH3	Q9UM47-1.2	A957R	Neutral	0.009
NOTCH3	Q9UM47-1.2	A957S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A957T	Neutral	0.002
NOTCH3	Q9UM47-1.2	A957V	Neutral	0.002
NOTCH3	Q9UM47-1.2	A957W	Neutral	0.152
NOTCH3	Q9UM47-1.2	A957Y	Neutral	0.041
NOTCH3	Q9UM47-1.2	H958A	Neutral	0.439
NOTCH3	Q9UM47-1.2	H958C	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	H958D	Neutral	0.16
NOTCH3	Q9UM47-1.2	H958E	Neutral	0.043
NOTCH3	Q9UM47-1.2	H958F	Neutral	0.166
NOTCH3	Q9UM47-1.2	H958G	Neutral	0.421
NOTCH3	Q9UM47-1.2	H958I	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	H958K	Neutral	0.165
NOTCH3	Q9UM47-1.2	H958L	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	H958M	Neutral	0.484
NOTCH3	Q9UM47-1.2	H958N	Neutral	0.009
NOTCH3	Q9UM47-1.2	H958P	Neutral	0.462
NOTCH3	Q9UM47-1.2	H958Q	Neutral	0.043
NOTCH3	Q9UM47-1.2	H958R	Neutral	0.04
NOTCH3	Q9UM47-1.2	H958S	Neutral	0.15
NOTCH3	Q9UM47-1.2	H958T	Neutral	0.464
NOTCH3	Q9UM47-1.2	H958V	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	H958W	Neutral	0.449
NOTCH3	Q9UM47-1.2	H958Y	Neutral	0.002
NOTCH3	Q9UM47-1.2	C959A	Pathogenic	0.508
NOTCH3	Q9UM47-1.2	C959D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C959E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C959F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	C959G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C959H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C959I	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C959K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C959L	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C959M	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C959N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C959P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C959Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C959R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C959S	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	C959T	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	C959V	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	C959W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C959Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	Q960A	Neutral	0.437
NOTCH3	Q9UM47-1.2	Q960C	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	Q960D	Neutral	0.158
NOTCH3	Q9UM47-1.2	Q960E	Neutral	0.01
NOTCH3	Q9UM47-1.2	Q960F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	Q960G	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	Q960H	Neutral	0.168
NOTCH3	Q9UM47-1.2	Q960I	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	Q960K	Neutral	0.04
NOTCH3	Q9UM47-1.2	Q960L	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	Q960M	Neutral	0.166
NOTCH3	Q9UM47-1.2	Q960N	Neutral	0.16
NOTCH3	Q9UM47-1.2	Q960P	Neutral	0.46
NOTCH3	Q9UM47-1.2	Q960R	Neutral	0.038
NOTCH3	Q9UM47-1.2	Q960S	Neutral	0.148
NOTCH3	Q9UM47-1.2	Q960T	Neutral	0.462
NOTCH3	Q9UM47-1.2	Q960V	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	Q960W	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	Q960Y	Neutral	0.458
NOTCH3	Q9UM47-1.2	H961A	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	H961C	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	H961D	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	H961E	Neutral	0.25
NOTCH3	Q9UM47-1.2	H961F	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	H961G	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	H961I	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	H961K	Pathogenic	0.596
NOTCH3	Q9UM47-1.2	H961L	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	H961M	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	H961N	Neutral	0.065
NOTCH3	Q9UM47-1.2	H961P	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	H961Q	Neutral	0.253
NOTCH3	Q9UM47-1.2	H961R	Neutral	0.236
NOTCH3	Q9UM47-1.2	H961S	Pathogenic	0.568
NOTCH3	Q9UM47-1.2	H961T	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	H961V	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	H961W	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	H961Y	Neutral	0.015
NOTCH3	Q9UM47-1.2	E962A	Neutral	0.247
NOTCH3	Q9UM47-1.2	E962C	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	E962D	Neutral	0.004
NOTCH3	Q9UM47-1.2	E962F	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	E962G	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	E962H	Neutral	0.075
NOTCH3	Q9UM47-1.2	E962I	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	E962K	Neutral	0.016
NOTCH3	Q9UM47-1.2	E962L	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	E962M	Pathogenic	0.625
NOTCH3	Q9UM47-1.2	E962N	Neutral	0.074
NOTCH3	Q9UM47-1.2	E962P	Neutral	0.264
NOTCH3	Q9UM47-1.2	E962Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	E962R	Neutral	0.068
NOTCH3	Q9UM47-1.2	E962S	Neutral	0.068
NOTCH3	Q9UM47-1.2	E962T	Neutral	0.266
NOTCH3	Q9UM47-1.2	E962V	Pathogenic	0.635
NOTCH3	Q9UM47-1.2	E962W	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	E962Y	Pathogenic	0.609
NOTCH3	Q9UM47-1.2	A963C	Neutral	0.005
NOTCH3	Q9UM47-1.2	A963D	Neutral	0.087
NOTCH3	Q9UM47-1.2	A963E	Neutral	0.019
NOTCH3	Q9UM47-1.2	A963F	Neutral	0.075
NOTCH3	Q9UM47-1.2	A963G	Neutral	0.005
NOTCH3	Q9UM47-1.2	A963H	Neutral	0.079
NOTCH3	Q9UM47-1.2	A963I	Neutral	0.018
NOTCH3	Q9UM47-1.2	A963K	Neutral	0.017
NOTCH3	Q9UM47-1.2	A963L	Neutral	0.018
NOTCH3	Q9UM47-1.2	A963M	Neutral	0.018
NOTCH3	Q9UM47-1.2	A963N	Neutral	0.086
NOTCH3	Q9UM47-1.2	A963P	Neutral	0.021
NOTCH3	Q9UM47-1.2	A963Q	Neutral	0.019
NOTCH3	Q9UM47-1.2	A963R	Neutral	0.017
NOTCH3	Q9UM47-1.2	A963S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A963T	Neutral	0.005
NOTCH3	Q9UM47-1.2	A963V	Neutral	0.004
NOTCH3	Q9UM47-1.2	A963W	Neutral	0.25
NOTCH3	Q9UM47-1.2	A963Y	Neutral	0.073
NOTCH3	Q9UM47-1.2	D964A	Neutral	0.279
NOTCH3	Q9UM47-1.2	D964C	Pathogenic	0.656
NOTCH3	Q9UM47-1.2	D964E	Neutral	0.001
NOTCH3	Q9UM47-1.2	D964F	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	D964G	Neutral	0.073
NOTCH3	Q9UM47-1.2	D964H	Neutral	0.077
NOTCH3	Q9UM47-1.2	D964I	Pathogenic	0.633
NOTCH3	Q9UM47-1.2	D964K	Neutral	0.072
NOTCH3	Q9UM47-1.2	D964L	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	D964M	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	D964N	Neutral	0.004
NOTCH3	Q9UM47-1.2	D964P	Neutral	0.085
NOTCH3	Q9UM47-1.2	D964Q	Neutral	0.018
NOTCH3	Q9UM47-1.2	D964R	Neutral	0.253
NOTCH3	Q9UM47-1.2	D964S	Neutral	0.019
NOTCH3	Q9UM47-1.2	D964T	Neutral	0.085
NOTCH3	Q9UM47-1.2	D964V	Pathogenic	0.649
NOTCH3	Q9UM47-1.2	D964W	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	D964Y	Pathogenic	0.616
NOTCH3	Q9UM47-1.2	P965A	Neutral	0.034
NOTCH3	Q9UM47-1.2	P965C	Neutral	0.44
NOTCH3	Q9UM47-1.2	P965D	Neutral	0.037
NOTCH3	Q9UM47-1.2	P965E	Neutral	0.035
NOTCH3	Q9UM47-1.2	P965F	Pathogenic	0.755
NOTCH3	Q9UM47-1.2	P965G	Neutral	0.13
NOTCH3	Q9UM47-1.2	P965H	Neutral	0.136
NOTCH3	Q9UM47-1.2	P965I	Neutral	0.414
NOTCH3	Q9UM47-1.2	P965K	Neutral	0.032
NOTCH3	Q9UM47-1.2	P965L	Neutral	0.414
NOTCH3	Q9UM47-1.2	P965M	Neutral	0.134
NOTCH3	Q9UM47-1.2	P965N	Neutral	0.148
NOTCH3	Q9UM47-1.2	P965Q	Neutral	0.034
NOTCH3	Q9UM47-1.2	P965R	Neutral	0.124
NOTCH3	Q9UM47-1.2	P965S	Neutral	0.035
NOTCH3	Q9UM47-1.2	P965T	Neutral	0.037
NOTCH3	Q9UM47-1.2	P965V	Neutral	0.142
NOTCH3	Q9UM47-1.2	P965W	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	P965Y	Neutral	0.396
NOTCH3	Q9UM47-1.2	C966A	Pathogenic	0.508
NOTCH3	Q9UM47-1.2	C966D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C966E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C966F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	C966G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C966H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C966I	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C966K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C966L	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C966M	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C966N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C966P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C966Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C966R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C966S	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	C966T	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	C966V	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	C966W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C966Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	L967A	Neutral	0.02
NOTCH3	Q9UM47-1.2	L967C	Neutral	0.021
NOTCH3	Q9UM47-1.2	L967D	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	L967E	Neutral	0.335
NOTCH3	Q9UM47-1.2	L967F	Neutral	0.005
NOTCH3	Q9UM47-1.2	L967G	Pathogenic	0.643
NOTCH3	Q9UM47-1.2	L967H	Neutral	0.341
NOTCH3	Q9UM47-1.2	L967I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L967K	Neutral	0.101
NOTCH3	Q9UM47-1.2	L967M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L967N	Neutral	0.324
NOTCH3	Q9UM47-1.2	L967P	Neutral	0.316
NOTCH3	Q9UM47-1.2	L967Q	Neutral	0.101
NOTCH3	Q9UM47-1.2	L967R	Neutral	0.097
NOTCH3	Q9UM47-1.2	L967S	Neutral	0.087
NOTCH3	Q9UM47-1.2	L967T	Neutral	0.022
NOTCH3	Q9UM47-1.2	L967V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L967W	Neutral	0.09
NOTCH3	Q9UM47-1.2	L967Y	Neutral	0.023
NOTCH3	Q9UM47-1.2	S968A	Neutral	0.114
NOTCH3	Q9UM47-1.2	S968C	Pathogenic	0.722
NOTCH3	Q9UM47-1.2	S968D	Neutral	0.358
NOTCH3	Q9UM47-1.2	S968E	Neutral	0.342
NOTCH3	Q9UM47-1.2	S968F	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	S968G	Neutral	0.351
NOTCH3	Q9UM47-1.2	S968H	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	S968I	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	S968K	Neutral	0.321
NOTCH3	Q9UM47-1.2	S968L	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	S968M	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	S968N	Neutral	0.107
NOTCH3	Q9UM47-1.2	S968P	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	S968Q	Neutral	0.337
NOTCH3	Q9UM47-1.2	S968R	Pathogenic	0.672
NOTCH3	Q9UM47-1.2	S968T	Neutral	0.108
NOTCH3	Q9UM47-1.2	S968V	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	S968W	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	S968Y	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	R969A	Neutral	0.1
NOTCH3	Q9UM47-1.2	R969C	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	R969D	Neutral	0.356
NOTCH3	Q9UM47-1.2	R969E	Neutral	0.028
NOTCH3	Q9UM47-1.2	R969F	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	R969G	Neutral	0.32
NOTCH3	Q9UM47-1.2	R969H	Neutral	0.029
NOTCH3	Q9UM47-1.2	R969I	Pathogenic	0.744
NOTCH3	Q9UM47-1.2	R969K	Neutral	0.002
NOTCH3	Q9UM47-1.2	R969L	Neutral	0.39
NOTCH3	Q9UM47-1.2	R969M	Neutral	0.123
NOTCH3	Q9UM47-1.2	R969N	Neutral	0.026
NOTCH3	Q9UM47-1.2	R969P	Neutral	0.357
NOTCH3	Q9UM47-1.2	R969Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	R969S	Neutral	0.102
NOTCH3	Q9UM47-1.2	R969T	Neutral	0.11
NOTCH3	Q9UM47-1.2	R969V	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	R969W	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	R969Y	Neutral	0.404
NOTCH3	Q9UM47-1.2	P970A	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	P970C	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	P970D	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	P970E	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	P970F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P970G	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	P970H	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	P970I	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	P970K	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	P970L	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	P970M	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	P970N	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	P970Q	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	P970R	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	P970S	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	P970T	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	P970V	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	P970W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P970Y	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	C971A	Pathogenic	0.508
NOTCH3	Q9UM47-1.2	C971D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C971E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C971F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	C971G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C971H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C971I	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C971K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C971L	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C971M	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C971N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C971P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C971Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C971R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C971S	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	C971T	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	C971V	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	C971W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C971Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	L972A	Neutral	0.414
NOTCH3	Q9UM47-1.2	L972C	Neutral	0.43
NOTCH3	Q9UM47-1.2	L972D	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	L972E	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	L972F	Neutral	0.155
NOTCH3	Q9UM47-1.2	L972G	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	L972H	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	L972I	Neutral	0.009
NOTCH3	Q9UM47-1.2	L972K	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	L972M	Neutral	0.009
NOTCH3	Q9UM47-1.2	L972N	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	L972P	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	L972Q	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	L972R	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	L972S	Pathogenic	0.767
NOTCH3	Q9UM47-1.2	L972T	Neutral	0.438
NOTCH3	Q9UM47-1.2	L972V	Neutral	0.038
NOTCH3	Q9UM47-1.2	L972W	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	L972Y	Neutral	0.45
NOTCH3	Q9UM47-1.2	H973A	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	H973C	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	H973D	Neutral	0.393
NOTCH3	Q9UM47-1.2	H973E	Neutral	0.132
NOTCH3	Q9UM47-1.2	H973F	Neutral	0.404
NOTCH3	Q9UM47-1.2	H973G	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	H973I	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	H973K	Neutral	0.403
NOTCH3	Q9UM47-1.2	H973L	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	H973M	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	H973N	Neutral	0.031
NOTCH3	Q9UM47-1.2	H973P	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	H973Q	Neutral	0.134
NOTCH3	Q9UM47-1.2	H973R	Neutral	0.124
NOTCH3	Q9UM47-1.2	H973S	Neutral	0.375
NOTCH3	Q9UM47-1.2	H973T	Pathogenic	0.747
NOTCH3	Q9UM47-1.2	H973V	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	H973W	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	H973Y	Neutral	0.007
NOTCH3	Q9UM47-1.2	G974A	Neutral	0.076
NOTCH3	Q9UM47-1.2	G974C	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	G974D	Neutral	0.256
NOTCH3	Q9UM47-1.2	G974E	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	G974F	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	G974H	Pathogenic	0.584
NOTCH3	Q9UM47-1.2	G974I	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	G974K	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	G974L	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	G974M	Pathogenic	0.863
NOTCH3	Q9UM47-1.2	G974N	Neutral	0.069
NOTCH3	Q9UM47-1.2	G974P	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	G974Q	Pathogenic	0.588
NOTCH3	Q9UM47-1.2	G974R	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	G974S	Neutral	0.074
NOTCH3	Q9UM47-1.2	G974T	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	G974V	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	G974W	Pathogenic	0.545
NOTCH3	Q9UM47-1.2	G974Y	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	G975A	Neutral	0.154
NOTCH3	Q9UM47-1.2	G975C	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	G975D	Neutral	0.432
NOTCH3	Q9UM47-1.2	G975E	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	G975F	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	G975H	Pathogenic	0.756
NOTCH3	Q9UM47-1.2	G975I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	G975K	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	G975L	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	G975M	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	G975N	Neutral	0.141
NOTCH3	Q9UM47-1.2	G975P	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	G975Q	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	G975R	Pathogenic	0.736
NOTCH3	Q9UM47-1.2	G975S	Neutral	0.151
NOTCH3	Q9UM47-1.2	G975T	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	G975V	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	G975W	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	G975Y	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	V976A	Neutral	0.016
NOTCH3	Q9UM47-1.2	V976C	Neutral	0.074
NOTCH3	Q9UM47-1.2	V976D	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	V976E	Neutral	0.282
NOTCH3	Q9UM47-1.2	V976F	Neutral	0.072
NOTCH3	Q9UM47-1.2	V976G	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	V976H	Pathogenic	0.631
NOTCH3	Q9UM47-1.2	V976I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V976K	Neutral	0.262
NOTCH3	Q9UM47-1.2	V976L	Neutral	0.004
NOTCH3	Q9UM47-1.2	V976M	Neutral	0.004
NOTCH3	Q9UM47-1.2	V976N	Pathogenic	0.636
NOTCH3	Q9UM47-1.2	V976P	Neutral	0.271
NOTCH3	Q9UM47-1.2	V976Q	Neutral	0.277
NOTCH3	Q9UM47-1.2	V976R	Pathogenic	0.606
NOTCH3	Q9UM47-1.2	V976S	Neutral	0.259
NOTCH3	Q9UM47-1.2	V976T	Neutral	0.018
NOTCH3	Q9UM47-1.2	V976W	Pathogenic	0.59
NOTCH3	Q9UM47-1.2	V976Y	Neutral	0.07
NOTCH3	Q9UM47-1.2	C977A	Pathogenic	0.508
NOTCH3	Q9UM47-1.2	C977D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C977E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C977F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	C977G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C977H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C977I	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C977K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C977L	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C977M	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C977N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C977P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C977Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C977R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C977S	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	C977T	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	C977V	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	C977W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C977Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	S978A	Neutral	0.0
NOTCH3	Q9UM47-1.2	S978C	Neutral	0.005
NOTCH3	Q9UM47-1.2	S978D	Neutral	0.001
NOTCH3	Q9UM47-1.2	S978E	Neutral	0.001
NOTCH3	Q9UM47-1.2	S978F	Neutral	0.017
NOTCH3	Q9UM47-1.2	S978G	Neutral	0.001
NOTCH3	Q9UM47-1.2	S978H	Neutral	0.004
NOTCH3	Q9UM47-1.2	S978I	Neutral	0.018
NOTCH3	Q9UM47-1.2	S978K	Neutral	0.001
NOTCH3	Q9UM47-1.2	S978L	Neutral	0.018
NOTCH3	Q9UM47-1.2	S978M	Neutral	0.004
NOTCH3	Q9UM47-1.2	S978N	Neutral	0.0
NOTCH3	Q9UM47-1.2	S978P	Neutral	0.004
NOTCH3	Q9UM47-1.2	S978Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	S978R	Neutral	0.004
NOTCH3	Q9UM47-1.2	S978T	Neutral	0.0
NOTCH3	Q9UM47-1.2	S978V	Neutral	0.019
NOTCH3	Q9UM47-1.2	S978W	Neutral	0.066
NOTCH3	Q9UM47-1.2	S978Y	Neutral	0.016
NOTCH3	Q9UM47-1.2	A979C	Neutral	0.007
NOTCH3	Q9UM47-1.2	A979D	Neutral	0.128
NOTCH3	Q9UM47-1.2	A979E	Neutral	0.029
NOTCH3	Q9UM47-1.2	A979F	Neutral	0.111
NOTCH3	Q9UM47-1.2	A979G	Neutral	0.007
NOTCH3	Q9UM47-1.2	A979H	Neutral	0.116
NOTCH3	Q9UM47-1.2	A979I	Neutral	0.028
NOTCH3	Q9UM47-1.2	A979K	Neutral	0.027
NOTCH3	Q9UM47-1.2	A979L	Neutral	0.028
NOTCH3	Q9UM47-1.2	A979M	Neutral	0.028
NOTCH3	Q9UM47-1.2	A979N	Neutral	0.126
NOTCH3	Q9UM47-1.2	A979P	Neutral	0.031
NOTCH3	Q9UM47-1.2	A979Q	Neutral	0.029
NOTCH3	Q9UM47-1.2	A979R	Neutral	0.025
NOTCH3	Q9UM47-1.2	A979S	Neutral	0.002
NOTCH3	Q9UM47-1.2	A979T	Neutral	0.007
NOTCH3	Q9UM47-1.2	A979V	Neutral	0.007
NOTCH3	Q9UM47-1.2	A979W	Neutral	0.338
NOTCH3	Q9UM47-1.2	A979Y	Neutral	0.108
NOTCH3	Q9UM47-1.2	A980C	Neutral	0.004
NOTCH3	Q9UM47-1.2	A980D	Neutral	0.075
NOTCH3	Q9UM47-1.2	A980E	Neutral	0.016
NOTCH3	Q9UM47-1.2	A980F	Neutral	0.064
NOTCH3	Q9UM47-1.2	A980G	Neutral	0.004
NOTCH3	Q9UM47-1.2	A980H	Neutral	0.067
NOTCH3	Q9UM47-1.2	A980I	Neutral	0.015
NOTCH3	Q9UM47-1.2	A980K	Neutral	0.015
NOTCH3	Q9UM47-1.2	A980L	Neutral	0.015
NOTCH3	Q9UM47-1.2	A980M	Neutral	0.015
NOTCH3	Q9UM47-1.2	A980N	Neutral	0.073
NOTCH3	Q9UM47-1.2	A980P	Neutral	0.017
NOTCH3	Q9UM47-1.2	A980Q	Neutral	0.016
NOTCH3	Q9UM47-1.2	A980R	Neutral	0.014
NOTCH3	Q9UM47-1.2	A980S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A980T	Neutral	0.004
NOTCH3	Q9UM47-1.2	A980V	Neutral	0.004
NOTCH3	Q9UM47-1.2	A980W	Neutral	0.219
NOTCH3	Q9UM47-1.2	A980Y	Neutral	0.062
NOTCH3	Q9UM47-1.2	H981A	Neutral	0.151
NOTCH3	Q9UM47-1.2	H981C	Neutral	0.467
NOTCH3	Q9UM47-1.2	H981D	Neutral	0.041
NOTCH3	Q9UM47-1.2	H981E	Neutral	0.01
NOTCH3	Q9UM47-1.2	H981F	Neutral	0.043
NOTCH3	Q9UM47-1.2	H981G	Neutral	0.142
NOTCH3	Q9UM47-1.2	H981I	Neutral	0.493
NOTCH3	Q9UM47-1.2	H981K	Neutral	0.043
NOTCH3	Q9UM47-1.2	H981L	Neutral	0.493
NOTCH3	Q9UM47-1.2	H981M	Neutral	0.176
NOTCH3	Q9UM47-1.2	H981N	Neutral	0.002
NOTCH3	Q9UM47-1.2	H981P	Neutral	0.163
NOTCH3	Q9UM47-1.2	H981Q	Neutral	0.01
NOTCH3	Q9UM47-1.2	H981R	Neutral	0.009
NOTCH3	Q9UM47-1.2	H981S	Neutral	0.038
NOTCH3	Q9UM47-1.2	H981T	Neutral	0.164
NOTCH3	Q9UM47-1.2	H981V	Neutral	0.486
NOTCH3	Q9UM47-1.2	H981W	Neutral	0.156
NOTCH3	Q9UM47-1.2	H981Y	Neutral	0.0
NOTCH3	Q9UM47-1.2	P982A	Neutral	0.018
NOTCH3	Q9UM47-1.2	P982C	Neutral	0.292
NOTCH3	Q9UM47-1.2	P982D	Neutral	0.02
NOTCH3	Q9UM47-1.2	P982E	Neutral	0.019
NOTCH3	Q9UM47-1.2	P982F	Pathogenic	0.617
NOTCH3	Q9UM47-1.2	P982G	Neutral	0.073
NOTCH3	Q9UM47-1.2	P982H	Neutral	0.076
NOTCH3	Q9UM47-1.2	P982I	Neutral	0.27
NOTCH3	Q9UM47-1.2	P982K	Neutral	0.017
NOTCH3	Q9UM47-1.2	P982L	Neutral	0.27
NOTCH3	Q9UM47-1.2	P982M	Neutral	0.075
NOTCH3	Q9UM47-1.2	P982N	Neutral	0.083
NOTCH3	Q9UM47-1.2	P982Q	Neutral	0.018
NOTCH3	Q9UM47-1.2	P982R	Neutral	0.069
NOTCH3	Q9UM47-1.2	P982S	Neutral	0.019
NOTCH3	Q9UM47-1.2	P982T	Neutral	0.02
NOTCH3	Q9UM47-1.2	P982V	Neutral	0.08
NOTCH3	Q9UM47-1.2	P982W	Pathogenic	0.592
NOTCH3	Q9UM47-1.2	P982Y	Neutral	0.256
NOTCH3	Q9UM47-1.2	G983A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G983C	Neutral	0.16
NOTCH3	Q9UM47-1.2	G983D	Neutral	0.009
NOTCH3	Q9UM47-1.2	G983E	Neutral	0.037
NOTCH3	Q9UM47-1.2	G983F	Neutral	0.137
NOTCH3	Q9UM47-1.2	G983H	Neutral	0.036
NOTCH3	Q9UM47-1.2	G983I	Neutral	0.431
NOTCH3	Q9UM47-1.2	G983K	Neutral	0.034
NOTCH3	Q9UM47-1.2	G983L	Neutral	0.43
NOTCH3	Q9UM47-1.2	G983M	Neutral	0.142
NOTCH3	Q9UM47-1.2	G983N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G983P	Neutral	0.04
NOTCH3	Q9UM47-1.2	G983Q	Neutral	0.036
NOTCH3	Q9UM47-1.2	G983R	Neutral	0.032
NOTCH3	Q9UM47-1.2	G983S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G983T	Neutral	0.039
NOTCH3	Q9UM47-1.2	G983V	Neutral	0.151
NOTCH3	Q9UM47-1.2	G983W	Neutral	0.031
NOTCH3	Q9UM47-1.2	G983Y	Neutral	0.134
NOTCH3	Q9UM47-1.2	F984A	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	F984C	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	F984D	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	F984E	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	F984G	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	F984H	Neutral	0.359
NOTCH3	Q9UM47-1.2	F984I	Neutral	0.11
NOTCH3	Q9UM47-1.2	F984K	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	F984L	Neutral	0.11
NOTCH3	Q9UM47-1.2	F984M	Neutral	0.111
NOTCH3	Q9UM47-1.2	F984N	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	F984P	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	F984Q	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	F984R	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	F984S	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	F984T	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	F984V	Neutral	0.345
NOTCH3	Q9UM47-1.2	F984W	Neutral	0.025
NOTCH3	Q9UM47-1.2	F984Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	R985A	Neutral	0.268
NOTCH3	Q9UM47-1.2	R985C	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	R985D	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	R985E	Neutral	0.086
NOTCH3	Q9UM47-1.2	R985F	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	R985G	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	R985H	Neutral	0.089
NOTCH3	Q9UM47-1.2	R985I	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	R985K	Neutral	0.005
NOTCH3	Q9UM47-1.2	R985L	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	R985M	Neutral	0.315
NOTCH3	Q9UM47-1.2	R985N	Neutral	0.082
NOTCH3	Q9UM47-1.2	R985P	Pathogenic	0.647
NOTCH3	Q9UM47-1.2	R985Q	Neutral	0.021
NOTCH3	Q9UM47-1.2	R985S	Neutral	0.272
NOTCH3	Q9UM47-1.2	R985T	Neutral	0.288
NOTCH3	Q9UM47-1.2	R985V	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	R985W	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	R985Y	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	C986A	Neutral	0.492
NOTCH3	Q9UM47-1.2	C986D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C986E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C986F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C986G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C986H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C986I	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C986K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C986L	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C986M	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C986N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C986P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C986Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C986R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C986S	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C986T	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C986V	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C986W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C986Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	T987A	Neutral	0.085
NOTCH3	Q9UM47-1.2	T987C	Neutral	0.314
NOTCH3	Q9UM47-1.2	T987D	Neutral	0.319
NOTCH3	Q9UM47-1.2	T987E	Neutral	0.307
NOTCH3	Q9UM47-1.2	T987F	Pathogenic	0.647
NOTCH3	Q9UM47-1.2	T987G	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	T987H	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	T987I	Neutral	0.296
NOTCH3	Q9UM47-1.2	T987K	Neutral	0.287
NOTCH3	Q9UM47-1.2	T987L	Neutral	0.296
NOTCH3	Q9UM47-1.2	T987M	Neutral	0.295
NOTCH3	Q9UM47-1.2	T987N	Neutral	0.093
NOTCH3	Q9UM47-1.2	T987P	Neutral	0.317
NOTCH3	Q9UM47-1.2	T987Q	Neutral	0.302
NOTCH3	Q9UM47-1.2	T987R	Neutral	0.277
NOTCH3	Q9UM47-1.2	T987S	Neutral	0.021
NOTCH3	Q9UM47-1.2	T987V	Neutral	0.09
NOTCH3	Q9UM47-1.2	T987W	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	T987Y	Pathogenic	0.64
NOTCH3	Q9UM47-1.2	C988A	Pathogenic	0.501
NOTCH3	Q9UM47-1.2	C988D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C988E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C988F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	C988G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C988H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C988I	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C988K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C988L	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C988M	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C988N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C988P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C988Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C988R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C988S	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	C988T	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	C988V	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C988W	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	C988Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	L989A	Neutral	0.003
NOTCH3	Q9UM47-1.2	L989C	Neutral	0.003
NOTCH3	Q9UM47-1.2	L989D	Neutral	0.218
NOTCH3	Q9UM47-1.2	L989E	Neutral	0.061
NOTCH3	Q9UM47-1.2	L989F	Neutral	0.001
NOTCH3	Q9UM47-1.2	L989G	Neutral	0.19
NOTCH3	Q9UM47-1.2	L989H	Neutral	0.063
NOTCH3	Q9UM47-1.2	L989I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L989K	Neutral	0.014
NOTCH3	Q9UM47-1.2	L989M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L989N	Neutral	0.059
NOTCH3	Q9UM47-1.2	L989P	Neutral	0.057
NOTCH3	Q9UM47-1.2	L989Q	Neutral	0.014
NOTCH3	Q9UM47-1.2	L989R	Neutral	0.014
NOTCH3	Q9UM47-1.2	L989S	Neutral	0.012
NOTCH3	Q9UM47-1.2	L989T	Neutral	0.003
NOTCH3	Q9UM47-1.2	L989V	Neutral	0.0
NOTCH3	Q9UM47-1.2	L989W	Neutral	0.013
NOTCH3	Q9UM47-1.2	L989Y	Neutral	0.003
NOTCH3	Q9UM47-1.2	E990A	Neutral	0.01
NOTCH3	Q9UM47-1.2	E990C	Neutral	0.497
NOTCH3	Q9UM47-1.2	E990D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E990F	Neutral	0.177
NOTCH3	Q9UM47-1.2	E990G	Neutral	0.039
NOTCH3	Q9UM47-1.2	E990H	Neutral	0.002
NOTCH3	Q9UM47-1.2	E990I	Neutral	0.184
NOTCH3	Q9UM47-1.2	E990K	Neutral	0.0
NOTCH3	Q9UM47-1.2	E990L	Neutral	0.184
NOTCH3	Q9UM47-1.2	E990M	Neutral	0.047
NOTCH3	Q9UM47-1.2	E990N	Neutral	0.002
NOTCH3	Q9UM47-1.2	E990P	Neutral	0.01
NOTCH3	Q9UM47-1.2	E990Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E990R	Neutral	0.002
NOTCH3	Q9UM47-1.2	E990S	Neutral	0.002
NOTCH3	Q9UM47-1.2	E990T	Neutral	0.011
NOTCH3	Q9UM47-1.2	E990V	Neutral	0.049
NOTCH3	Q9UM47-1.2	E990W	Neutral	0.163
NOTCH3	Q9UM47-1.2	E990Y	Neutral	0.044
NOTCH3	Q9UM47-1.2	S991A	Neutral	0.0
NOTCH3	Q9UM47-1.2	S991C	Neutral	0.004
NOTCH3	Q9UM47-1.2	S991D	Neutral	0.001
NOTCH3	Q9UM47-1.2	S991E	Neutral	0.001
NOTCH3	Q9UM47-1.2	S991F	Neutral	0.016
NOTCH3	Q9UM47-1.2	S991G	Neutral	0.001
NOTCH3	Q9UM47-1.2	S991H	Neutral	0.004
NOTCH3	Q9UM47-1.2	S991I	Neutral	0.016
NOTCH3	Q9UM47-1.2	S991K	Neutral	0.001
NOTCH3	Q9UM47-1.2	S991L	Neutral	0.016
NOTCH3	Q9UM47-1.2	S991M	Neutral	0.004
NOTCH3	Q9UM47-1.2	S991N	Neutral	0.0
NOTCH3	Q9UM47-1.2	S991P	Neutral	0.004
NOTCH3	Q9UM47-1.2	S991Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	S991R	Neutral	0.003
NOTCH3	Q9UM47-1.2	S991T	Neutral	0.0
NOTCH3	Q9UM47-1.2	S991V	Neutral	0.018
NOTCH3	Q9UM47-1.2	S991W	Neutral	0.062
NOTCH3	Q9UM47-1.2	S991Y	Neutral	0.015
NOTCH3	Q9UM47-1.2	F992A	Pathogenic	0.636
NOTCH3	Q9UM47-1.2	F992C	Pathogenic	0.651
NOTCH3	Q9UM47-1.2	F992D	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	F992E	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	F992G	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	F992H	Neutral	0.318
NOTCH3	Q9UM47-1.2	F992I	Neutral	0.094
NOTCH3	Q9UM47-1.2	F992K	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	F992L	Neutral	0.094
NOTCH3	Q9UM47-1.2	F992M	Neutral	0.094
NOTCH3	Q9UM47-1.2	F992N	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	F992P	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	F992Q	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	F992R	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	F992S	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	F992T	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	F992V	Neutral	0.306
NOTCH3	Q9UM47-1.2	F992W	Neutral	0.021
NOTCH3	Q9UM47-1.2	F992Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	T993A	Neutral	0.257
NOTCH3	Q9UM47-1.2	T993C	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	T993D	Pathogenic	0.635
NOTCH3	Q9UM47-1.2	T993E	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	T993F	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	T993G	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	T993H	Pathogenic	0.878
NOTCH3	Q9UM47-1.2	T993I	Pathogenic	0.61
NOTCH3	Q9UM47-1.2	T993K	Pathogenic	0.599
NOTCH3	Q9UM47-1.2	T993L	Pathogenic	0.61
NOTCH3	Q9UM47-1.2	T993M	Pathogenic	0.609
NOTCH3	Q9UM47-1.2	T993N	Neutral	0.276
NOTCH3	Q9UM47-1.2	T993P	Pathogenic	0.633
NOTCH3	Q9UM47-1.2	T993Q	Pathogenic	0.617
NOTCH3	Q9UM47-1.2	T993R	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	T993S	Neutral	0.072
NOTCH3	Q9UM47-1.2	T993V	Neutral	0.269
NOTCH3	Q9UM47-1.2	T993W	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	T993Y	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	G994A	Neutral	0.243
NOTCH3	Q9UM47-1.2	G994C	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	G994D	Pathogenic	0.572
NOTCH3	Q9UM47-1.2	G994E	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	G994F	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G994H	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	G994I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G994K	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G994L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G994M	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G994N	Neutral	0.223
NOTCH3	Q9UM47-1.2	G994P	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	G994Q	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	G994R	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	G994S	Neutral	0.238
NOTCH3	Q9UM47-1.2	G994T	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	G994V	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G994W	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	G994Y	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	P995A	Neutral	0.004
NOTCH3	Q9UM47-1.2	P995C	Neutral	0.082
NOTCH3	Q9UM47-1.2	P995D	Neutral	0.004
NOTCH3	Q9UM47-1.2	P995E	Neutral	0.004
NOTCH3	Q9UM47-1.2	P995F	Neutral	0.26
NOTCH3	Q9UM47-1.2	P995G	Neutral	0.017
NOTCH3	Q9UM47-1.2	P995H	Neutral	0.018
NOTCH3	Q9UM47-1.2	P995I	Neutral	0.075
NOTCH3	Q9UM47-1.2	P995K	Neutral	0.004
NOTCH3	Q9UM47-1.2	P995L	Neutral	0.074
NOTCH3	Q9UM47-1.2	P995M	Neutral	0.017
NOTCH3	Q9UM47-1.2	P995N	Neutral	0.019
NOTCH3	Q9UM47-1.2	P995Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	P995R	Neutral	0.016
NOTCH3	Q9UM47-1.2	P995S	Neutral	0.004
NOTCH3	Q9UM47-1.2	P995T	Neutral	0.004
NOTCH3	Q9UM47-1.2	P995V	Neutral	0.019
NOTCH3	Q9UM47-1.2	P995W	Neutral	0.24
NOTCH3	Q9UM47-1.2	P995Y	Neutral	0.07
NOTCH3	Q9UM47-1.2	Q996A	Neutral	0.051
NOTCH3	Q9UM47-1.2	Q996C	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	Q996D	Neutral	0.013
NOTCH3	Q9UM47-1.2	Q996E	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q996F	Pathogenic	0.556
NOTCH3	Q9UM47-1.2	Q996G	Neutral	0.186
NOTCH3	Q9UM47-1.2	Q996H	Neutral	0.014
NOTCH3	Q9UM47-1.2	Q996I	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	Q996K	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q996L	Neutral	0.223
NOTCH3	Q9UM47-1.2	Q996M	Neutral	0.014
NOTCH3	Q9UM47-1.2	Q996N	Neutral	0.013
NOTCH3	Q9UM47-1.2	Q996P	Neutral	0.056
NOTCH3	Q9UM47-1.2	Q996R	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q996S	Neutral	0.012
NOTCH3	Q9UM47-1.2	Q996T	Neutral	0.056
NOTCH3	Q9UM47-1.2	Q996V	Neutral	0.223
NOTCH3	Q9UM47-1.2	Q996W	Neutral	0.199
NOTCH3	Q9UM47-1.2	Q996Y	Neutral	0.055
NOTCH3	Q9UM47-1.2	C997A	Pathogenic	0.508
NOTCH3	Q9UM47-1.2	C997D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C997E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C997F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	C997G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C997H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C997I	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C997K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C997L	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C997M	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C997N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C997P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C997Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C997R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C997S	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	C997T	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	C997V	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	C997W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C997Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	Q998A	Pathogenic	0.675
NOTCH3	Q9UM47-1.2	Q998C	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	Q998D	Neutral	0.334
NOTCH3	Q9UM47-1.2	Q998E	Neutral	0.025
NOTCH3	Q9UM47-1.2	Q998F	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	Q998G	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	Q998H	Neutral	0.35
NOTCH3	Q9UM47-1.2	Q998I	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	Q998K	Neutral	0.1
NOTCH3	Q9UM47-1.2	Q998L	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	Q998M	Neutral	0.347
NOTCH3	Q9UM47-1.2	Q998N	Neutral	0.338
NOTCH3	Q9UM47-1.2	Q998P	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	Q998R	Neutral	0.096
NOTCH3	Q9UM47-1.2	Q998S	Neutral	0.318
NOTCH3	Q9UM47-1.2	Q998T	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	Q998V	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	Q998W	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	Q998Y	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	T999A	Neutral	0.03
NOTCH3	Q9UM47-1.2	T999C	Neutral	0.133
NOTCH3	Q9UM47-1.2	T999D	Neutral	0.135
NOTCH3	Q9UM47-1.2	T999E	Neutral	0.129
NOTCH3	Q9UM47-1.2	T999F	Neutral	0.38
NOTCH3	Q9UM47-1.2	T999G	Neutral	0.374
NOTCH3	Q9UM47-1.2	T999H	Neutral	0.392
NOTCH3	Q9UM47-1.2	T999I	Neutral	0.123
NOTCH3	Q9UM47-1.2	T999K	Neutral	0.118
NOTCH3	Q9UM47-1.2	T999L	Neutral	0.123
NOTCH3	Q9UM47-1.2	T999M	Neutral	0.122
NOTCH3	Q9UM47-1.2	T999N	Neutral	0.033
NOTCH3	Q9UM47-1.2	T999P	Neutral	0.134
NOTCH3	Q9UM47-1.2	T999Q	Neutral	0.126
NOTCH3	Q9UM47-1.2	T999R	Neutral	0.113
NOTCH3	Q9UM47-1.2	T999S	Neutral	0.007
NOTCH3	Q9UM47-1.2	T999V	Neutral	0.032
NOTCH3	Q9UM47-1.2	T999W	Neutral	0.355
NOTCH3	Q9UM47-1.2	T999Y	Neutral	0.373
NOTCH3	Q9UM47-1.2	L1000A	Neutral	0.333
NOTCH3	Q9UM47-1.2	L1000C	Neutral	0.348
NOTCH3	Q9UM47-1.2	L1000D	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L1000E	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	L1000F	Neutral	0.115
NOTCH3	Q9UM47-1.2	L1000G	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	L1000H	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	L1000I	Neutral	0.006
NOTCH3	Q9UM47-1.2	L1000K	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	L1000M	Neutral	0.007
NOTCH3	Q9UM47-1.2	L1000N	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	L1000P	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	L1000Q	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	L1000R	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	L1000S	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	L1000T	Neutral	0.356
NOTCH3	Q9UM47-1.2	L1000V	Neutral	0.027
NOTCH3	Q9UM47-1.2	L1000W	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	L1000Y	Neutral	0.367
NOTCH3	Q9UM47-1.2	V1001A	Neutral	0.376
NOTCH3	Q9UM47-1.2	V1001C	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	V1001D	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	V1001E	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	V1001F	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	V1001G	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	V1001H	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	V1001I	Neutral	0.007
NOTCH3	Q9UM47-1.2	V1001K	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	V1001L	Neutral	0.124
NOTCH3	Q9UM47-1.2	V1001M	Neutral	0.124
NOTCH3	Q9UM47-1.2	V1001N	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	V1001P	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	V1001Q	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	V1001R	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	V1001S	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	V1001T	Neutral	0.4
NOTCH3	Q9UM47-1.2	V1001W	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	V1001Y	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	D1002A	Neutral	0.384
NOTCH3	Q9UM47-1.2	D1002C	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	D1002E	Neutral	0.001
NOTCH3	Q9UM47-1.2	D1002F	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	D1002G	Neutral	0.113
NOTCH3	Q9UM47-1.2	D1002H	Neutral	0.119
NOTCH3	Q9UM47-1.2	D1002I	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	D1002K	Neutral	0.112
NOTCH3	Q9UM47-1.2	D1002L	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	D1002M	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	D1002N	Neutral	0.007
NOTCH3	Q9UM47-1.2	D1002P	Neutral	0.13
NOTCH3	Q9UM47-1.2	D1002Q	Neutral	0.029
NOTCH3	Q9UM47-1.2	D1002R	Neutral	0.353
NOTCH3	Q9UM47-1.2	D1002S	Neutral	0.03
NOTCH3	Q9UM47-1.2	D1002T	Neutral	0.13
NOTCH3	Q9UM47-1.2	D1002V	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	D1002W	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	D1002Y	Pathogenic	0.721
NOTCH3	Q9UM47-1.2	W1003A	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1003C	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	W1003D	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1003E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1003F	Pathogenic	0.583
NOTCH3	Q9UM47-1.2	W1003G	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	W1003H	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	W1003I	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1003K	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1003L	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	W1003M	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	W1003N	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1003P	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1003Q	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	W1003R	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1003S	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1003T	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	W1003V	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1003Y	Neutral	0.241
NOTCH3	Q9UM47-1.2	C1004A	Pathogenic	0.511
NOTCH3	Q9UM47-1.2	C1004D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1004E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1004F	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	C1004G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1004H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1004I	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C1004K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1004L	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C1004M	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C1004N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1004P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1004Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1004R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1004S	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	C1004T	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C1004V	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C1004W	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	C1004Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	S1005A	Neutral	0.007
NOTCH3	Q9UM47-1.2	S1005C	Neutral	0.118
NOTCH3	Q9UM47-1.2	S1005D	Neutral	0.028
NOTCH3	Q9UM47-1.2	S1005E	Neutral	0.026
NOTCH3	Q9UM47-1.2	S1005F	Neutral	0.337
NOTCH3	Q9UM47-1.2	S1005G	Neutral	0.027
NOTCH3	Q9UM47-1.2	S1005H	Neutral	0.105
NOTCH3	Q9UM47-1.2	S1005I	Neutral	0.347
NOTCH3	Q9UM47-1.2	S1005K	Neutral	0.024
NOTCH3	Q9UM47-1.2	S1005L	Neutral	0.347
NOTCH3	Q9UM47-1.2	S1005M	Neutral	0.104
NOTCH3	Q9UM47-1.2	S1005N	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1005P	Neutral	0.116
NOTCH3	Q9UM47-1.2	S1005Q	Neutral	0.026
NOTCH3	Q9UM47-1.2	S1005R	Neutral	0.095
NOTCH3	Q9UM47-1.2	S1005T	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1005V	Neutral	0.362
NOTCH3	Q9UM47-1.2	S1005W	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	S1005Y	Neutral	0.33
NOTCH3	Q9UM47-1.2	R1006A	Neutral	0.099
NOTCH3	Q9UM47-1.2	R1006C	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	R1006D	Neutral	0.353
NOTCH3	Q9UM47-1.2	R1006E	Neutral	0.028
NOTCH3	Q9UM47-1.2	R1006F	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	R1006G	Neutral	0.318
NOTCH3	Q9UM47-1.2	R1006H	Neutral	0.029
NOTCH3	Q9UM47-1.2	R1006I	Pathogenic	0.743
NOTCH3	Q9UM47-1.2	R1006K	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1006L	Neutral	0.388
NOTCH3	Q9UM47-1.2	R1006M	Neutral	0.122
NOTCH3	Q9UM47-1.2	R1006N	Neutral	0.026
NOTCH3	Q9UM47-1.2	R1006P	Neutral	0.355
NOTCH3	Q9UM47-1.2	R1006Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	R1006S	Neutral	0.101
NOTCH3	Q9UM47-1.2	R1006T	Neutral	0.109
NOTCH3	Q9UM47-1.2	R1006V	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	R1006W	Pathogenic	0.75
NOTCH3	Q9UM47-1.2	R1006Y	Neutral	0.402
NOTCH3	Q9UM47-1.2	Q1007A	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1007C	Neutral	0.028
NOTCH3	Q9UM47-1.2	Q1007D	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1007E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1007F	Neutral	0.029
NOTCH3	Q9UM47-1.2	Q1007G	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q1007H	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1007I	Neutral	0.03
NOTCH3	Q9UM47-1.2	Q1007K	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1007L	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q1007M	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1007N	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1007P	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1007R	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1007S	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1007T	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1007V	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q1007W	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q1007Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	P1008A	Pathogenic	0.526
NOTCH3	Q9UM47-1.2	P1008C	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	P1008D	Pathogenic	0.55
NOTCH3	Q9UM47-1.2	P1008E	Pathogenic	0.532
NOTCH3	Q9UM47-1.2	P1008F	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	P1008G	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	P1008H	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	P1008I	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	P1008K	Pathogenic	0.508
NOTCH3	Q9UM47-1.2	P1008L	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	P1008M	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	P1008N	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	P1008Q	Pathogenic	0.526
NOTCH3	Q9UM47-1.2	P1008R	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	P1008S	Pathogenic	0.533
NOTCH3	Q9UM47-1.2	P1008T	Pathogenic	0.546
NOTCH3	Q9UM47-1.2	P1008V	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	P1008W	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	P1008Y	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	C1009A	Pathogenic	0.507
NOTCH3	Q9UM47-1.2	C1009D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1009E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1009F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	C1009G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1009H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1009I	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C1009K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1009L	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C1009M	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	C1009N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1009P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1009Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1009R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1009S	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	C1009T	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	C1009V	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C1009W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C1009Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	Q1010A	Neutral	0.066
NOTCH3	Q9UM47-1.2	Q1010C	Pathogenic	0.613
NOTCH3	Q9UM47-1.2	Q1010D	Neutral	0.017
NOTCH3	Q9UM47-1.2	Q1010E	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1010F	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	Q1010G	Neutral	0.23
NOTCH3	Q9UM47-1.2	Q1010H	Neutral	0.018
NOTCH3	Q9UM47-1.2	Q1010I	Pathogenic	0.631
NOTCH3	Q9UM47-1.2	Q1010K	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q1010L	Neutral	0.273
NOTCH3	Q9UM47-1.2	Q1010M	Neutral	0.018
NOTCH3	Q9UM47-1.2	Q1010N	Neutral	0.017
NOTCH3	Q9UM47-1.2	Q1010P	Neutral	0.072
NOTCH3	Q9UM47-1.2	Q1010R	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q1010S	Neutral	0.016
NOTCH3	Q9UM47-1.2	Q1010T	Neutral	0.073
NOTCH3	Q9UM47-1.2	Q1010V	Neutral	0.273
NOTCH3	Q9UM47-1.2	Q1010W	Neutral	0.245
NOTCH3	Q9UM47-1.2	Q1010Y	Neutral	0.071
NOTCH3	Q9UM47-1.2	N1011A	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	N1011C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N1011D	Neutral	0.14
NOTCH3	Q9UM47-1.2	N1011E	Neutral	0.419
NOTCH3	Q9UM47-1.2	N1011F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N1011G	Neutral	0.387
NOTCH3	Q9UM47-1.2	N1011H	Neutral	0.133
NOTCH3	Q9UM47-1.2	N1011I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N1011K	Neutral	0.395
NOTCH3	Q9UM47-1.2	N1011L	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N1011M	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	N1011P	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	N1011Q	Neutral	0.415
NOTCH3	Q9UM47-1.2	N1011R	Neutral	0.383
NOTCH3	Q9UM47-1.2	N1011S	Neutral	0.133
NOTCH3	Q9UM47-1.2	N1011T	Neutral	0.43
NOTCH3	Q9UM47-1.2	N1011V	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N1011W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N1011Y	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	G1012A	Neutral	0.062
NOTCH3	Q9UM47-1.2	G1012C	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	G1012D	Neutral	0.217
NOTCH3	Q9UM47-1.2	G1012E	Pathogenic	0.541
NOTCH3	Q9UM47-1.2	G1012F	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	G1012H	Pathogenic	0.531
NOTCH3	Q9UM47-1.2	G1012I	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1012K	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	G1012L	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1012M	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	G1012N	Neutral	0.056
NOTCH3	Q9UM47-1.2	G1012P	Pathogenic	0.559
NOTCH3	Q9UM47-1.2	G1012Q	Pathogenic	0.535
NOTCH3	Q9UM47-1.2	G1012R	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	G1012S	Neutral	0.061
NOTCH3	Q9UM47-1.2	G1012T	Pathogenic	0.555
NOTCH3	Q9UM47-1.2	G1012V	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	G1012W	Neutral	0.492
NOTCH3	Q9UM47-1.2	G1012Y	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	G1013A	Neutral	0.158
NOTCH3	Q9UM47-1.2	G1013C	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	G1013D	Neutral	0.439
NOTCH3	Q9UM47-1.2	G1013E	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	G1013F	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	G1013H	Pathogenic	0.761
NOTCH3	Q9UM47-1.2	G1013I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	G1013K	Pathogenic	0.75
NOTCH3	Q9UM47-1.2	G1013L	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	G1013M	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	G1013N	Neutral	0.144
NOTCH3	Q9UM47-1.2	G1013P	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	G1013Q	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	G1013R	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	G1013S	Neutral	0.155
NOTCH3	Q9UM47-1.2	G1013T	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	G1013V	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	G1013W	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	G1013Y	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	R1014A	Neutral	0.06
NOTCH3	Q9UM47-1.2	R1014C	Pathogenic	0.588
NOTCH3	Q9UM47-1.2	R1014D	Neutral	0.24
NOTCH3	Q9UM47-1.2	R1014E	Neutral	0.016
NOTCH3	Q9UM47-1.2	R1014F	Pathogenic	0.635
NOTCH3	Q9UM47-1.2	R1014G	Neutral	0.212
NOTCH3	Q9UM47-1.2	R1014H	Neutral	0.017
NOTCH3	Q9UM47-1.2	R1014I	Pathogenic	0.625
NOTCH3	Q9UM47-1.2	R1014K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1014L	Neutral	0.268
NOTCH3	Q9UM47-1.2	R1014M	Neutral	0.074
NOTCH3	Q9UM47-1.2	R1014N	Neutral	0.015
NOTCH3	Q9UM47-1.2	R1014P	Neutral	0.241
NOTCH3	Q9UM47-1.2	R1014Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	R1014S	Neutral	0.061
NOTCH3	Q9UM47-1.2	R1014T	Neutral	0.066
NOTCH3	Q9UM47-1.2	R1014V	Pathogenic	0.606
NOTCH3	Q9UM47-1.2	R1014W	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	R1014Y	Neutral	0.279
NOTCH3	Q9UM47-1.2	C1015A	Pathogenic	0.507
NOTCH3	Q9UM47-1.2	C1015D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1015E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1015F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	C1015G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1015H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1015I	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C1015K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1015L	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C1015M	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	C1015N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1015P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1015Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1015R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1015S	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	C1015T	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	C1015V	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C1015W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C1015Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	V1016A	Neutral	0.013
NOTCH3	Q9UM47-1.2	V1016C	Neutral	0.059
NOTCH3	Q9UM47-1.2	V1016D	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	V1016E	Neutral	0.236
NOTCH3	Q9UM47-1.2	V1016F	Neutral	0.057
NOTCH3	Q9UM47-1.2	V1016G	Pathogenic	0.532
NOTCH3	Q9UM47-1.2	V1016H	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	V1016I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V1016K	Neutral	0.218
NOTCH3	Q9UM47-1.2	V1016L	Neutral	0.003
NOTCH3	Q9UM47-1.2	V1016M	Neutral	0.003
NOTCH3	Q9UM47-1.2	V1016N	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	V1016P	Neutral	0.226
NOTCH3	Q9UM47-1.2	V1016Q	Neutral	0.231
NOTCH3	Q9UM47-1.2	V1016R	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	V1016S	Neutral	0.216
NOTCH3	Q9UM47-1.2	V1016T	Neutral	0.014
NOTCH3	Q9UM47-1.2	V1016W	Pathogenic	0.531
NOTCH3	Q9UM47-1.2	V1016Y	Neutral	0.056
NOTCH3	Q9UM47-1.2	Q1017A	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	Q1017C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	Q1017D	Neutral	0.414
NOTCH3	Q9UM47-1.2	Q1017E	Neutral	0.035
NOTCH3	Q9UM47-1.2	Q1017F	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	Q1017G	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	Q1017H	Neutral	0.432
NOTCH3	Q9UM47-1.2	Q1017I	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	Q1017K	Neutral	0.136
NOTCH3	Q9UM47-1.2	Q1017L	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	Q1017M	Neutral	0.428
NOTCH3	Q9UM47-1.2	Q1017N	Neutral	0.419
NOTCH3	Q9UM47-1.2	Q1017P	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	Q1017R	Neutral	0.13
NOTCH3	Q9UM47-1.2	Q1017S	Neutral	0.397
NOTCH3	Q9UM47-1.2	Q1017T	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	Q1017V	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	Q1017W	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	Q1017Y	Pathogenic	0.761
NOTCH3	Q9UM47-1.2	T1018A	Neutral	0.034
NOTCH3	Q9UM47-1.2	T1018C	Neutral	0.149
NOTCH3	Q9UM47-1.2	T1018D	Neutral	0.152
NOTCH3	Q9UM47-1.2	T1018E	Neutral	0.145
NOTCH3	Q9UM47-1.2	T1018F	Neutral	0.413
NOTCH3	Q9UM47-1.2	T1018G	Neutral	0.408
NOTCH3	Q9UM47-1.2	T1018H	Neutral	0.426
NOTCH3	Q9UM47-1.2	T1018I	Neutral	0.139
NOTCH3	Q9UM47-1.2	T1018K	Neutral	0.134
NOTCH3	Q9UM47-1.2	T1018L	Neutral	0.139
NOTCH3	Q9UM47-1.2	T1018M	Neutral	0.138
NOTCH3	Q9UM47-1.2	T1018N	Neutral	0.038
NOTCH3	Q9UM47-1.2	T1018P	Neutral	0.151
NOTCH3	Q9UM47-1.2	T1018Q	Neutral	0.142
NOTCH3	Q9UM47-1.2	T1018R	Neutral	0.128
NOTCH3	Q9UM47-1.2	T1018S	Neutral	0.008
NOTCH3	Q9UM47-1.2	T1018V	Neutral	0.037
NOTCH3	Q9UM47-1.2	T1018W	Neutral	0.388
NOTCH3	Q9UM47-1.2	T1018Y	Neutral	0.406
NOTCH3	Q9UM47-1.2	G1019A	Neutral	0.006
NOTCH3	Q9UM47-1.2	G1019C	Neutral	0.346
NOTCH3	Q9UM47-1.2	G1019D	Neutral	0.024
NOTCH3	Q9UM47-1.2	G1019E	Neutral	0.096
NOTCH3	Q9UM47-1.2	G1019F	Neutral	0.306
NOTCH3	Q9UM47-1.2	G1019H	Neutral	0.092
NOTCH3	Q9UM47-1.2	G1019I	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	G1019K	Neutral	0.088
NOTCH3	Q9UM47-1.2	G1019L	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	G1019M	Neutral	0.314
NOTCH3	Q9UM47-1.2	G1019N	Neutral	0.005
NOTCH3	Q9UM47-1.2	G1019P	Neutral	0.102
NOTCH3	Q9UM47-1.2	G1019Q	Neutral	0.094
NOTCH3	Q9UM47-1.2	G1019R	Neutral	0.084
NOTCH3	Q9UM47-1.2	G1019S	Neutral	0.006
NOTCH3	Q9UM47-1.2	G1019T	Neutral	0.101
NOTCH3	Q9UM47-1.2	G1019V	Neutral	0.33
NOTCH3	Q9UM47-1.2	G1019W	Neutral	0.08
NOTCH3	Q9UM47-1.2	G1019Y	Neutral	0.299
NOTCH3	Q9UM47-1.2	A1020C	Neutral	0.052
NOTCH3	Q9UM47-1.2	A1020D	Pathogenic	0.526
NOTCH3	Q9UM47-1.2	A1020E	Neutral	0.185
NOTCH3	Q9UM47-1.2	A1020F	Neutral	0.484
NOTCH3	Q9UM47-1.2	A1020G	Neutral	0.051
NOTCH3	Q9UM47-1.2	A1020H	Neutral	0.498
NOTCH3	Q9UM47-1.2	A1020I	Neutral	0.177
NOTCH3	Q9UM47-1.2	A1020K	Neutral	0.171
NOTCH3	Q9UM47-1.2	A1020L	Neutral	0.177
NOTCH3	Q9UM47-1.2	A1020M	Neutral	0.176
NOTCH3	Q9UM47-1.2	A1020N	Pathogenic	0.52
NOTCH3	Q9UM47-1.2	A1020P	Neutral	0.195
NOTCH3	Q9UM47-1.2	A1020Q	Neutral	0.181
NOTCH3	Q9UM47-1.2	A1020R	Neutral	0.164
NOTCH3	Q9UM47-1.2	A1020S	Neutral	0.012
NOTCH3	Q9UM47-1.2	A1020T	Neutral	0.05
NOTCH3	Q9UM47-1.2	A1020V	Neutral	0.048
NOTCH3	Q9UM47-1.2	A1020W	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	A1020Y	Neutral	0.477
NOTCH3	Q9UM47-1.2	Y1021A	Neutral	0.205
NOTCH3	Q9UM47-1.2	Y1021C	Neutral	0.216
NOTCH3	Q9UM47-1.2	Y1021D	Pathogenic	0.565
NOTCH3	Q9UM47-1.2	Y1021E	Neutral	0.234
NOTCH3	Q9UM47-1.2	Y1021F	Neutral	0.0
NOTCH3	Q9UM47-1.2	Y1021G	Pathogenic	0.522
NOTCH3	Q9UM47-1.2	Y1021H	Neutral	0.001
NOTCH3	Q9UM47-1.2	Y1021I	Neutral	0.066
NOTCH3	Q9UM47-1.2	Y1021K	Neutral	0.253
NOTCH3	Q9UM47-1.2	Y1021L	Neutral	0.066
NOTCH3	Q9UM47-1.2	Y1021M	Neutral	0.066
NOTCH3	Q9UM47-1.2	Y1021N	Neutral	0.225
NOTCH3	Q9UM47-1.2	Y1021P	Pathogenic	0.561
NOTCH3	Q9UM47-1.2	Y1021Q	Neutral	0.064
NOTCH3	Q9UM47-1.2	Y1021R	Neutral	0.252
NOTCH3	Q9UM47-1.2	Y1021S	Neutral	0.209
NOTCH3	Q9UM47-1.2	Y1021T	Neutral	0.222
NOTCH3	Q9UM47-1.2	Y1021V	Neutral	0.061
NOTCH3	Q9UM47-1.2	Y1021W	Neutral	0.001
NOTCH3	Q9UM47-1.2	C1022A	Pathogenic	0.507
NOTCH3	Q9UM47-1.2	C1022D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1022E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1022F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	C1022G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1022H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1022I	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C1022K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1022L	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C1022M	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C1022N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1022P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1022Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1022R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1022S	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	C1022T	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	C1022V	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C1022W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C1022Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	L1023A	Neutral	0.033
NOTCH3	Q9UM47-1.2	L1023C	Neutral	0.035
NOTCH3	Q9UM47-1.2	L1023D	Pathogenic	0.782
NOTCH3	Q9UM47-1.2	L1023E	Neutral	0.457
NOTCH3	Q9UM47-1.2	L1023F	Neutral	0.009
NOTCH3	Q9UM47-1.2	L1023G	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	L1023H	Neutral	0.464
NOTCH3	Q9UM47-1.2	L1023I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1023K	Neutral	0.158
NOTCH3	Q9UM47-1.2	L1023M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1023N	Neutral	0.444
NOTCH3	Q9UM47-1.2	L1023P	Neutral	0.436
NOTCH3	Q9UM47-1.2	L1023Q	Neutral	0.158
NOTCH3	Q9UM47-1.2	L1023R	Neutral	0.152
NOTCH3	Q9UM47-1.2	L1023S	Neutral	0.138
NOTCH3	Q9UM47-1.2	L1023T	Neutral	0.037
NOTCH3	Q9UM47-1.2	L1023V	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1023W	Neutral	0.142
NOTCH3	Q9UM47-1.2	L1023Y	Neutral	0.038
NOTCH3	Q9UM47-1.2	C1024A	Neutral	0.494
NOTCH3	Q9UM47-1.2	C1024D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1024E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1024F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	C1024G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1024H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1024I	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C1024K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1024L	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C1024M	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C1024N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1024P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1024Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1024R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1024S	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C1024T	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C1024V	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C1024W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C1024Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	P1025A	Neutral	0.072
NOTCH3	Q9UM47-1.2	P1025C	Pathogenic	0.633
NOTCH3	Q9UM47-1.2	P1025D	Neutral	0.078
NOTCH3	Q9UM47-1.2	P1025E	Neutral	0.073
NOTCH3	Q9UM47-1.2	P1025F	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	P1025G	Neutral	0.247
NOTCH3	Q9UM47-1.2	P1025H	Neutral	0.257
NOTCH3	Q9UM47-1.2	P1025I	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	P1025K	Neutral	0.067
NOTCH3	Q9UM47-1.2	P1025L	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	P1025M	Neutral	0.253
NOTCH3	Q9UM47-1.2	P1025N	Neutral	0.275
NOTCH3	Q9UM47-1.2	P1025Q	Neutral	0.072
NOTCH3	Q9UM47-1.2	P1025R	Neutral	0.237
NOTCH3	Q9UM47-1.2	P1025S	Neutral	0.074
NOTCH3	Q9UM47-1.2	P1025T	Neutral	0.077
NOTCH3	Q9UM47-1.2	P1025V	Neutral	0.267
NOTCH3	Q9UM47-1.2	P1025W	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	P1025Y	Pathogenic	0.59
NOTCH3	Q9UM47-1.2	P1026A	Neutral	0.033
NOTCH3	Q9UM47-1.2	P1026C	Neutral	0.434
NOTCH3	Q9UM47-1.2	P1026D	Neutral	0.036
NOTCH3	Q9UM47-1.2	P1026E	Neutral	0.034
NOTCH3	Q9UM47-1.2	P1026F	Pathogenic	0.75
NOTCH3	Q9UM47-1.2	P1026G	Neutral	0.127
NOTCH3	Q9UM47-1.2	P1026H	Neutral	0.133
NOTCH3	Q9UM47-1.2	P1026I	Neutral	0.407
NOTCH3	Q9UM47-1.2	P1026K	Neutral	0.031
NOTCH3	Q9UM47-1.2	P1026L	Neutral	0.407
NOTCH3	Q9UM47-1.2	P1026M	Neutral	0.131
NOTCH3	Q9UM47-1.2	P1026N	Neutral	0.144
NOTCH3	Q9UM47-1.2	P1026Q	Neutral	0.033
NOTCH3	Q9UM47-1.2	P1026R	Neutral	0.121
NOTCH3	Q9UM47-1.2	P1026S	Neutral	0.034
NOTCH3	Q9UM47-1.2	P1026T	Neutral	0.036
NOTCH3	Q9UM47-1.2	P1026V	Neutral	0.139
NOTCH3	Q9UM47-1.2	P1026W	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	P1026Y	Neutral	0.39
NOTCH3	Q9UM47-1.2	G1027A	Neutral	0.179
NOTCH3	Q9UM47-1.2	G1027C	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	G1027D	Neutral	0.476
NOTCH3	Q9UM47-1.2	G1027E	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	G1027F	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	G1027H	Pathogenic	0.788
NOTCH3	Q9UM47-1.2	G1027I	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	G1027K	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	G1027L	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	G1027M	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	G1027N	Neutral	0.163
NOTCH3	Q9UM47-1.2	G1027P	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	G1027Q	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	G1027R	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	G1027S	Neutral	0.175
NOTCH3	Q9UM47-1.2	G1027T	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	G1027V	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	G1027W	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	G1027Y	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	W1028A	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1028C	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1028D	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1028E	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1028F	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	W1028G	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1028H	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1028I	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1028K	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1028L	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1028M	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	W1028N	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1028P	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1028Q	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1028R	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1028S	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1028T	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1028V	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1028Y	Pathogenic	0.578
NOTCH3	Q9UM47-1.2	S1029A	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1029C	Neutral	0.051
NOTCH3	Q9UM47-1.2	S1029D	Neutral	0.011
NOTCH3	Q9UM47-1.2	S1029E	Neutral	0.011
NOTCH3	Q9UM47-1.2	S1029F	Neutral	0.169
NOTCH3	Q9UM47-1.2	S1029G	Neutral	0.011
NOTCH3	Q9UM47-1.2	S1029H	Neutral	0.045
NOTCH3	Q9UM47-1.2	S1029I	Neutral	0.175
NOTCH3	Q9UM47-1.2	S1029K	Neutral	0.01
NOTCH3	Q9UM47-1.2	S1029L	Neutral	0.175
NOTCH3	Q9UM47-1.2	S1029M	Neutral	0.044
NOTCH3	Q9UM47-1.2	S1029N	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1029P	Neutral	0.05
NOTCH3	Q9UM47-1.2	S1029Q	Neutral	0.01
NOTCH3	Q9UM47-1.2	S1029R	Neutral	0.04
NOTCH3	Q9UM47-1.2	S1029T	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1029V	Neutral	0.185
NOTCH3	Q9UM47-1.2	S1029W	Neutral	0.454
NOTCH3	Q9UM47-1.2	S1029Y	Neutral	0.164
NOTCH3	Q9UM47-1.2	G1030A	Neutral	0.235
NOTCH3	Q9UM47-1.2	G1030C	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G1030D	Pathogenic	0.561
NOTCH3	Q9UM47-1.2	G1030E	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	G1030F	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G1030H	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	G1030I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1030K	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	G1030L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1030M	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1030N	Neutral	0.216
NOTCH3	Q9UM47-1.2	G1030P	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	G1030Q	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	G1030R	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G1030S	Neutral	0.23
NOTCH3	Q9UM47-1.2	G1030T	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	G1030V	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	G1030W	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	G1030Y	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	R1031A	Neutral	0.051
NOTCH3	Q9UM47-1.2	R1031C	Pathogenic	0.547
NOTCH3	Q9UM47-1.2	R1031D	Neutral	0.211
NOTCH3	Q9UM47-1.2	R1031E	Neutral	0.014
NOTCH3	Q9UM47-1.2	R1031F	Pathogenic	0.595
NOTCH3	Q9UM47-1.2	R1031G	Neutral	0.185
NOTCH3	Q9UM47-1.2	R1031H	Neutral	0.014
NOTCH3	Q9UM47-1.2	R1031I	Pathogenic	0.585
NOTCH3	Q9UM47-1.2	R1031K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1031L	Neutral	0.236
NOTCH3	Q9UM47-1.2	R1031M	Neutral	0.063
NOTCH3	Q9UM47-1.2	R1031N	Neutral	0.013
NOTCH3	Q9UM47-1.2	R1031P	Neutral	0.212
NOTCH3	Q9UM47-1.2	R1031Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R1031S	Neutral	0.052
NOTCH3	Q9UM47-1.2	R1031T	Neutral	0.056
NOTCH3	Q9UM47-1.2	R1031V	Pathogenic	0.566
NOTCH3	Q9UM47-1.2	R1031W	Pathogenic	0.594
NOTCH3	Q9UM47-1.2	R1031Y	Neutral	0.247
NOTCH3	Q9UM47-1.2	L1032A	Neutral	0.032
NOTCH3	Q9UM47-1.2	L1032C	Neutral	0.034
NOTCH3	Q9UM47-1.2	L1032D	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	L1032E	Neutral	0.447
NOTCH3	Q9UM47-1.2	L1032F	Neutral	0.008
NOTCH3	Q9UM47-1.2	L1032G	Pathogenic	0.743
NOTCH3	Q9UM47-1.2	L1032H	Neutral	0.454
NOTCH3	Q9UM47-1.2	L1032I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1032K	Neutral	0.153
NOTCH3	Q9UM47-1.2	L1032M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1032N	Neutral	0.434
NOTCH3	Q9UM47-1.2	L1032P	Neutral	0.426
NOTCH3	Q9UM47-1.2	L1032Q	Neutral	0.153
NOTCH3	Q9UM47-1.2	L1032R	Neutral	0.147
NOTCH3	Q9UM47-1.2	L1032S	Neutral	0.133
NOTCH3	Q9UM47-1.2	L1032T	Neutral	0.035
NOTCH3	Q9UM47-1.2	L1032V	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1032W	Neutral	0.137
NOTCH3	Q9UM47-1.2	L1032Y	Neutral	0.037
NOTCH3	Q9UM47-1.2	C1033A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C1033D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1033E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1033F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C1033G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1033H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1033I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1033K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1033L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1033M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C1033N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1033P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1033Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1033R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1033S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C1033T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C1033V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C1033W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C1033Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	D1034A	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	D1034C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D1034E	Neutral	0.033
NOTCH3	Q9UM47-1.2	D1034F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1034G	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	D1034H	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	D1034I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1034K	Pathogenic	0.744
NOTCH3	Q9UM47-1.2	D1034L	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	D1034M	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1034N	Neutral	0.14
NOTCH3	Q9UM47-1.2	D1034P	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	D1034Q	Neutral	0.41
NOTCH3	Q9UM47-1.2	D1034R	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	D1034S	Neutral	0.415
NOTCH3	Q9UM47-1.2	D1034T	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	D1034V	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D1034W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1034Y	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	I1035A	Neutral	0.358
NOTCH3	Q9UM47-1.2	I1035C	Neutral	0.374
NOTCH3	Q9UM47-1.2	I1035D	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	I1035E	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	I1035F	Neutral	0.126
NOTCH3	Q9UM47-1.2	I1035G	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	I1035H	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	I1035K	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	I1035L	Neutral	0.007
NOTCH3	Q9UM47-1.2	I1035M	Neutral	0.032
NOTCH3	Q9UM47-1.2	I1035N	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	I1035P	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	I1035Q	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	I1035R	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	I1035S	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	I1035T	Neutral	0.382
NOTCH3	Q9UM47-1.2	I1035V	Neutral	0.001
NOTCH3	Q9UM47-1.2	I1035W	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	I1035Y	Neutral	0.393
NOTCH3	Q9UM47-1.2	R1036A	Neutral	0.032
NOTCH3	Q9UM47-1.2	R1036C	Neutral	0.422
NOTCH3	Q9UM47-1.2	R1036D	Neutral	0.139
NOTCH3	Q9UM47-1.2	R1036E	Neutral	0.008
NOTCH3	Q9UM47-1.2	R1036F	Neutral	0.47
NOTCH3	Q9UM47-1.2	R1036G	Neutral	0.121
NOTCH3	Q9UM47-1.2	R1036H	Neutral	0.009
NOTCH3	Q9UM47-1.2	R1036I	Neutral	0.46
NOTCH3	Q9UM47-1.2	R1036K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R1036L	Neutral	0.157
NOTCH3	Q9UM47-1.2	R1036M	Neutral	0.039
NOTCH3	Q9UM47-1.2	R1036N	Neutral	0.008
NOTCH3	Q9UM47-1.2	R1036P	Neutral	0.14
NOTCH3	Q9UM47-1.2	R1036Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1036S	Neutral	0.032
NOTCH3	Q9UM47-1.2	R1036T	Neutral	0.035
NOTCH3	Q9UM47-1.2	R1036V	Neutral	0.44
NOTCH3	Q9UM47-1.2	R1036W	Neutral	0.469
NOTCH3	Q9UM47-1.2	R1036Y	Neutral	0.165
NOTCH3	Q9UM47-1.2	S1037A	Neutral	0.01
NOTCH3	Q9UM47-1.2	S1037C	Neutral	0.173
NOTCH3	Q9UM47-1.2	S1037D	Neutral	0.043
NOTCH3	Q9UM47-1.2	S1037E	Neutral	0.04
NOTCH3	Q9UM47-1.2	S1037F	Neutral	0.442
NOTCH3	Q9UM47-1.2	S1037G	Neutral	0.042
NOTCH3	Q9UM47-1.2	S1037H	Neutral	0.155
NOTCH3	Q9UM47-1.2	S1037I	Neutral	0.452
NOTCH3	Q9UM47-1.2	S1037K	Neutral	0.037
NOTCH3	Q9UM47-1.2	S1037L	Neutral	0.452
NOTCH3	Q9UM47-1.2	S1037M	Neutral	0.153
NOTCH3	Q9UM47-1.2	S1037N	Neutral	0.01
NOTCH3	Q9UM47-1.2	S1037P	Neutral	0.17
NOTCH3	Q9UM47-1.2	S1037Q	Neutral	0.039
NOTCH3	Q9UM47-1.2	S1037R	Neutral	0.141
NOTCH3	Q9UM47-1.2	S1037T	Neutral	0.01
NOTCH3	Q9UM47-1.2	S1037V	Neutral	0.469
NOTCH3	Q9UM47-1.2	S1037W	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	S1037Y	Neutral	0.434
NOTCH3	Q9UM47-1.2	L1038A	Neutral	0.03
NOTCH3	Q9UM47-1.2	L1038C	Neutral	0.032
NOTCH3	Q9UM47-1.2	L1038D	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	L1038E	Neutral	0.429
NOTCH3	Q9UM47-1.2	L1038F	Neutral	0.008
NOTCH3	Q9UM47-1.2	L1038G	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	L1038H	Neutral	0.436
NOTCH3	Q9UM47-1.2	L1038I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1038K	Neutral	0.144
NOTCH3	Q9UM47-1.2	L1038M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1038N	Neutral	0.417
NOTCH3	Q9UM47-1.2	L1038P	Neutral	0.408
NOTCH3	Q9UM47-1.2	L1038Q	Neutral	0.144
NOTCH3	Q9UM47-1.2	L1038R	Neutral	0.138
NOTCH3	Q9UM47-1.2	L1038S	Neutral	0.125
NOTCH3	Q9UM47-1.2	L1038T	Neutral	0.033
NOTCH3	Q9UM47-1.2	L1038V	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1038W	Neutral	0.129
NOTCH3	Q9UM47-1.2	L1038Y	Neutral	0.034
NOTCH3	Q9UM47-1.2	P1039A	Neutral	0.045
NOTCH3	Q9UM47-1.2	P1039C	Pathogenic	0.509
NOTCH3	Q9UM47-1.2	P1039D	Neutral	0.049
NOTCH3	Q9UM47-1.2	P1039E	Neutral	0.046
NOTCH3	Q9UM47-1.2	P1039F	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	P1039G	Neutral	0.165
NOTCH3	Q9UM47-1.2	P1039H	Neutral	0.172
NOTCH3	Q9UM47-1.2	P1039I	Neutral	0.482
NOTCH3	Q9UM47-1.2	P1039K	Neutral	0.041
NOTCH3	Q9UM47-1.2	P1039L	Neutral	0.482
NOTCH3	Q9UM47-1.2	P1039M	Neutral	0.169
NOTCH3	Q9UM47-1.2	P1039N	Neutral	0.186
NOTCH3	Q9UM47-1.2	P1039Q	Neutral	0.045
NOTCH3	Q9UM47-1.2	P1039R	Neutral	0.158
NOTCH3	Q9UM47-1.2	P1039S	Neutral	0.046
NOTCH3	Q9UM47-1.2	P1039T	Neutral	0.048
NOTCH3	Q9UM47-1.2	P1039V	Neutral	0.18
NOTCH3	Q9UM47-1.2	P1039W	Pathogenic	0.785
NOTCH3	Q9UM47-1.2	P1039Y	Neutral	0.464
NOTCH3	Q9UM47-1.2	C1040A	Neutral	0.489
NOTCH3	Q9UM47-1.2	C1040D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1040E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1040F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C1040G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1040H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1040I	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C1040K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1040L	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C1040M	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	C1040N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1040P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1040Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1040R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1040S	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	C1040T	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C1040V	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C1040W	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	C1040Y	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	R1041A	Neutral	0.028
NOTCH3	Q9UM47-1.2	R1041C	Neutral	0.391
NOTCH3	Q9UM47-1.2	R1041D	Neutral	0.124
NOTCH3	Q9UM47-1.2	R1041E	Neutral	0.007
NOTCH3	Q9UM47-1.2	R1041F	Neutral	0.439
NOTCH3	Q9UM47-1.2	R1041G	Neutral	0.108
NOTCH3	Q9UM47-1.2	R1041H	Neutral	0.008
NOTCH3	Q9UM47-1.2	R1041I	Neutral	0.428
NOTCH3	Q9UM47-1.2	R1041K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R1041L	Neutral	0.141
NOTCH3	Q9UM47-1.2	R1041M	Neutral	0.035
NOTCH3	Q9UM47-1.2	R1041N	Neutral	0.007
NOTCH3	Q9UM47-1.2	R1041P	Neutral	0.125
NOTCH3	Q9UM47-1.2	R1041Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1041S	Neutral	0.028
NOTCH3	Q9UM47-1.2	R1041T	Neutral	0.031
NOTCH3	Q9UM47-1.2	R1041V	Neutral	0.409
NOTCH3	Q9UM47-1.2	R1041W	Neutral	0.438
NOTCH3	Q9UM47-1.2	R1041Y	Neutral	0.149
NOTCH3	Q9UM47-1.2	E1042A	Neutral	0.032
NOTCH3	Q9UM47-1.2	E1042C	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	E1042D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1042F	Neutral	0.427
NOTCH3	Q9UM47-1.2	E1042G	Neutral	0.124
NOTCH3	Q9UM47-1.2	E1042H	Neutral	0.008
NOTCH3	Q9UM47-1.2	E1042I	Neutral	0.438
NOTCH3	Q9UM47-1.2	E1042K	Neutral	0.002
NOTCH3	Q9UM47-1.2	E1042L	Neutral	0.437
NOTCH3	Q9UM47-1.2	E1042M	Neutral	0.145
NOTCH3	Q9UM47-1.2	E1042N	Neutral	0.008
NOTCH3	Q9UM47-1.2	E1042P	Neutral	0.035
NOTCH3	Q9UM47-1.2	E1042Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1042R	Neutral	0.007
NOTCH3	Q9UM47-1.2	E1042S	Neutral	0.007
NOTCH3	Q9UM47-1.2	E1042T	Neutral	0.036
NOTCH3	Q9UM47-1.2	E1042V	Neutral	0.151
NOTCH3	Q9UM47-1.2	E1042W	Neutral	0.402
NOTCH3	Q9UM47-1.2	E1042Y	Neutral	0.137
NOTCH3	Q9UM47-1.2	A1043C	Neutral	0.251
NOTCH3	Q9UM47-1.2	A1043D	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	A1043E	Pathogenic	0.583
NOTCH3	Q9UM47-1.2	A1043F	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	A1043G	Neutral	0.25
NOTCH3	Q9UM47-1.2	A1043H	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	A1043I	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	A1043K	Pathogenic	0.559
NOTCH3	Q9UM47-1.2	A1043L	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	A1043M	Pathogenic	0.569
NOTCH3	Q9UM47-1.2	A1043N	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	A1043P	Pathogenic	0.6
NOTCH3	Q9UM47-1.2	A1043Q	Pathogenic	0.577
NOTCH3	Q9UM47-1.2	A1043R	Pathogenic	0.547
NOTCH3	Q9UM47-1.2	A1043S	Neutral	0.072
NOTCH3	Q9UM47-1.2	A1043T	Neutral	0.245
NOTCH3	Q9UM47-1.2	A1043V	Neutral	0.238
NOTCH3	Q9UM47-1.2	A1043W	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	A1043Y	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	A1044C	Neutral	0.379
NOTCH3	Q9UM47-1.2	A1044D	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	A1044E	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	A1044F	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	A1044G	Neutral	0.378
NOTCH3	Q9UM47-1.2	A1044H	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	A1044I	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	A1044K	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	A1044L	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	A1044M	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	A1044N	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	A1044P	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	A1044Q	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	A1044R	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	A1044S	Neutral	0.123
NOTCH3	Q9UM47-1.2	A1044T	Neutral	0.371
NOTCH3	Q9UM47-1.2	A1044V	Neutral	0.362
NOTCH3	Q9UM47-1.2	A1044W	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	A1044Y	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	A1045C	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1045D	Neutral	0.089
NOTCH3	Q9UM47-1.2	A1045E	Neutral	0.02
NOTCH3	Q9UM47-1.2	A1045F	Neutral	0.076
NOTCH3	Q9UM47-1.2	A1045G	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1045H	Neutral	0.08
NOTCH3	Q9UM47-1.2	A1045I	Neutral	0.019
NOTCH3	Q9UM47-1.2	A1045K	Neutral	0.018
NOTCH3	Q9UM47-1.2	A1045L	Neutral	0.018
NOTCH3	Q9UM47-1.2	A1045M	Neutral	0.018
NOTCH3	Q9UM47-1.2	A1045N	Neutral	0.087
NOTCH3	Q9UM47-1.2	A1045P	Neutral	0.021
NOTCH3	Q9UM47-1.2	A1045Q	Neutral	0.019
NOTCH3	Q9UM47-1.2	A1045R	Neutral	0.017
NOTCH3	Q9UM47-1.2	A1045S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1045T	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1045V	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1045W	Neutral	0.252
NOTCH3	Q9UM47-1.2	A1045Y	Neutral	0.074
NOTCH3	Q9UM47-1.2	Q1046A	Neutral	0.261
NOTCH3	Q9UM47-1.2	Q1046C	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	Q1046D	Neutral	0.079
NOTCH3	Q9UM47-1.2	Q1046E	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q1046F	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	Q1046G	Pathogenic	0.599
NOTCH3	Q9UM47-1.2	Q1046H	Neutral	0.084
NOTCH3	Q9UM47-1.2	Q1046I	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	Q1046K	Neutral	0.019
NOTCH3	Q9UM47-1.2	Q1046L	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	Q1046M	Neutral	0.083
NOTCH3	Q9UM47-1.2	Q1046N	Neutral	0.08
NOTCH3	Q9UM47-1.2	Q1046P	Neutral	0.279
NOTCH3	Q9UM47-1.2	Q1046R	Neutral	0.018
NOTCH3	Q9UM47-1.2	Q1046S	Neutral	0.073
NOTCH3	Q9UM47-1.2	Q1046T	Neutral	0.281
NOTCH3	Q9UM47-1.2	Q1046V	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	Q1046W	Pathogenic	0.619
NOTCH3	Q9UM47-1.2	Q1046Y	Neutral	0.277
NOTCH3	Q9UM47-1.2	I1047A	Neutral	0.034
NOTCH3	Q9UM47-1.2	I1047C	Neutral	0.036
NOTCH3	Q9UM47-1.2	I1047D	Neutral	0.445
NOTCH3	Q9UM47-1.2	I1047E	Neutral	0.462
NOTCH3	Q9UM47-1.2	I1047F	Neutral	0.009
NOTCH3	Q9UM47-1.2	I1047G	Pathogenic	0.755
NOTCH3	Q9UM47-1.2	I1047H	Neutral	0.469
NOTCH3	Q9UM47-1.2	I1047K	Neutral	0.467
NOTCH3	Q9UM47-1.2	I1047L	Neutral	0.0
NOTCH3	Q9UM47-1.2	I1047M	Neutral	0.002
NOTCH3	Q9UM47-1.2	I1047N	Neutral	0.45
NOTCH3	Q9UM47-1.2	I1047P	Neutral	0.441
NOTCH3	Q9UM47-1.2	I1047Q	Neutral	0.466
NOTCH3	Q9UM47-1.2	I1047R	Neutral	0.454
NOTCH3	Q9UM47-1.2	I1047S	Neutral	0.141
NOTCH3	Q9UM47-1.2	I1047T	Neutral	0.037
NOTCH3	Q9UM47-1.2	I1047V	Neutral	0.0
NOTCH3	Q9UM47-1.2	I1047W	Neutral	0.435
NOTCH3	Q9UM47-1.2	I1047Y	Neutral	0.039
NOTCH3	Q9UM47-1.2	G1048A	Neutral	0.121
NOTCH3	Q9UM47-1.2	G1048C	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	G1048D	Neutral	0.364
NOTCH3	Q9UM47-1.2	G1048E	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	G1048F	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	G1048H	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	G1048I	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	G1048K	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	G1048L	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	G1048M	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	G1048N	Neutral	0.11
NOTCH3	Q9UM47-1.2	G1048P	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	G1048Q	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	G1048R	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	G1048S	Neutral	0.118
NOTCH3	Q9UM47-1.2	G1048T	Pathogenic	0.72
NOTCH3	Q9UM47-1.2	G1048V	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	G1048W	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	G1048Y	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	V1049A	Neutral	0.172
NOTCH3	Q9UM47-1.2	V1049C	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	V1049D	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	V1049E	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	V1049F	Neutral	0.494
NOTCH3	Q9UM47-1.2	V1049G	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	V1049H	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	V1049I	Neutral	0.002
NOTCH3	Q9UM47-1.2	V1049K	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	V1049L	Neutral	0.047
NOTCH3	Q9UM47-1.2	V1049M	Neutral	0.047
NOTCH3	Q9UM47-1.2	V1049N	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	V1049P	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	V1049Q	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	V1049R	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	V1049S	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	V1049T	Neutral	0.187
NOTCH3	Q9UM47-1.2	V1049W	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	V1049Y	Neutral	0.487
NOTCH3	Q9UM47-1.2	R1050A	Neutral	0.008
NOTCH3	Q9UM47-1.2	R1050C	Neutral	0.159
NOTCH3	Q9UM47-1.2	R1050D	Neutral	0.04
NOTCH3	Q9UM47-1.2	R1050E	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1050F	Neutral	0.187
NOTCH3	Q9UM47-1.2	R1050G	Neutral	0.034
NOTCH3	Q9UM47-1.2	R1050H	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1050I	Neutral	0.181
NOTCH3	Q9UM47-1.2	R1050K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R1050L	Neutral	0.046
NOTCH3	Q9UM47-1.2	R1050M	Neutral	0.011
NOTCH3	Q9UM47-1.2	R1050N	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1050P	Neutral	0.041
NOTCH3	Q9UM47-1.2	R1050Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	R1050S	Neutral	0.009
NOTCH3	Q9UM47-1.2	R1050T	Neutral	0.009
NOTCH3	Q9UM47-1.2	R1050V	Neutral	0.17
NOTCH3	Q9UM47-1.2	R1050W	Neutral	0.187
NOTCH3	Q9UM47-1.2	R1050Y	Neutral	0.049
NOTCH3	Q9UM47-1.2	L1051A	Neutral	0.014
NOTCH3	Q9UM47-1.2	L1051C	Neutral	0.015
NOTCH3	Q9UM47-1.2	L1051D	Pathogenic	0.602
NOTCH3	Q9UM47-1.2	L1051E	Neutral	0.263
NOTCH3	Q9UM47-1.2	L1051F	Neutral	0.004
NOTCH3	Q9UM47-1.2	L1051G	Pathogenic	0.561
NOTCH3	Q9UM47-1.2	L1051H	Neutral	0.268
NOTCH3	Q9UM47-1.2	L1051I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1051K	Neutral	0.074
NOTCH3	Q9UM47-1.2	L1051M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1051N	Neutral	0.253
NOTCH3	Q9UM47-1.2	L1051P	Neutral	0.247
NOTCH3	Q9UM47-1.2	L1051Q	Neutral	0.074
NOTCH3	Q9UM47-1.2	L1051R	Neutral	0.071
NOTCH3	Q9UM47-1.2	L1051S	Neutral	0.064
NOTCH3	Q9UM47-1.2	L1051T	Neutral	0.016
NOTCH3	Q9UM47-1.2	L1051V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1051W	Neutral	0.066
NOTCH3	Q9UM47-1.2	L1051Y	Neutral	0.017
NOTCH3	Q9UM47-1.2	E1052A	Neutral	0.058
NOTCH3	Q9UM47-1.2	E1052C	Pathogenic	0.864
NOTCH3	Q9UM47-1.2	E1052D	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1052F	Pathogenic	0.581
NOTCH3	Q9UM47-1.2	E1052G	Neutral	0.208
NOTCH3	Q9UM47-1.2	E1052H	Neutral	0.015
NOTCH3	Q9UM47-1.2	E1052I	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	E1052K	Neutral	0.003
NOTCH3	Q9UM47-1.2	E1052L	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	E1052M	Neutral	0.24
NOTCH3	Q9UM47-1.2	E1052N	Neutral	0.015
NOTCH3	Q9UM47-1.2	E1052P	Neutral	0.064
NOTCH3	Q9UM47-1.2	E1052Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1052R	Neutral	0.014
NOTCH3	Q9UM47-1.2	E1052S	Neutral	0.014
NOTCH3	Q9UM47-1.2	E1052T	Neutral	0.064
NOTCH3	Q9UM47-1.2	E1052V	Neutral	0.248
NOTCH3	Q9UM47-1.2	E1052W	Pathogenic	0.555
NOTCH3	Q9UM47-1.2	E1052Y	Neutral	0.228
NOTCH3	Q9UM47-1.2	Q1053A	Neutral	0.065
NOTCH3	Q9UM47-1.2	Q1053C	Pathogenic	0.61
NOTCH3	Q9UM47-1.2	Q1053D	Neutral	0.016
NOTCH3	Q9UM47-1.2	Q1053E	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1053F	Pathogenic	0.617
NOTCH3	Q9UM47-1.2	Q1053G	Neutral	0.227
NOTCH3	Q9UM47-1.2	Q1053H	Neutral	0.018
NOTCH3	Q9UM47-1.2	Q1053I	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	Q1053K	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q1053L	Neutral	0.27
NOTCH3	Q9UM47-1.2	Q1053M	Neutral	0.017
NOTCH3	Q9UM47-1.2	Q1053N	Neutral	0.017
NOTCH3	Q9UM47-1.2	Q1053P	Neutral	0.071
NOTCH3	Q9UM47-1.2	Q1053R	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q1053S	Neutral	0.015
NOTCH3	Q9UM47-1.2	Q1053T	Neutral	0.071
NOTCH3	Q9UM47-1.2	Q1053V	Neutral	0.27
NOTCH3	Q9UM47-1.2	Q1053W	Neutral	0.242
NOTCH3	Q9UM47-1.2	Q1053Y	Neutral	0.07
NOTCH3	Q9UM47-1.2	L1054A	Pathogenic	0.596
NOTCH3	Q9UM47-1.2	L1054C	Pathogenic	0.612
NOTCH3	Q9UM47-1.2	L1054D	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	L1054E	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	L1054F	Neutral	0.277
NOTCH3	Q9UM47-1.2	L1054G	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	L1054H	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	L1054I	Neutral	0.019
NOTCH3	Q9UM47-1.2	L1054K	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	L1054M	Neutral	0.019
NOTCH3	Q9UM47-1.2	L1054N	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	L1054P	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	L1054Q	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	L1054R	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	L1054S	Pathogenic	0.873
NOTCH3	Q9UM47-1.2	L1054T	Pathogenic	0.62
NOTCH3	Q9UM47-1.2	L1054V	Neutral	0.076
NOTCH3	Q9UM47-1.2	L1054W	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	L1054Y	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	C1055A	Pathogenic	0.503
NOTCH3	Q9UM47-1.2	C1055D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1055E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1055F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	C1055G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1055H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1055I	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C1055K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1055L	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C1055M	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C1055N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1055P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1055Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1055R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1055S	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C1055T	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	C1055V	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	C1055W	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	C1055Y	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	Q1056A	Neutral	0.215
NOTCH3	Q9UM47-1.2	Q1056C	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	Q1056D	Neutral	0.062
NOTCH3	Q9UM47-1.2	Q1056E	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q1056F	Pathogenic	0.864
NOTCH3	Q9UM47-1.2	Q1056G	Pathogenic	0.537
NOTCH3	Q9UM47-1.2	Q1056H	Neutral	0.066
NOTCH3	Q9UM47-1.2	Q1056I	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	Q1056K	Neutral	0.014
NOTCH3	Q9UM47-1.2	Q1056L	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	Q1056M	Neutral	0.065
NOTCH3	Q9UM47-1.2	Q1056N	Neutral	0.063
NOTCH3	Q9UM47-1.2	Q1056P	Neutral	0.231
NOTCH3	Q9UM47-1.2	Q1056R	Neutral	0.014
NOTCH3	Q9UM47-1.2	Q1056S	Neutral	0.058
NOTCH3	Q9UM47-1.2	Q1056T	Neutral	0.233
NOTCH3	Q9UM47-1.2	Q1056V	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	Q1056W	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	Q1056Y	Neutral	0.23
NOTCH3	Q9UM47-1.2	A1057C	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1057D	Neutral	0.078
NOTCH3	Q9UM47-1.2	A1057E	Neutral	0.017
NOTCH3	Q9UM47-1.2	A1057F	Neutral	0.067
NOTCH3	Q9UM47-1.2	A1057G	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1057H	Neutral	0.071
NOTCH3	Q9UM47-1.2	A1057I	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1057K	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1057L	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1057M	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1057N	Neutral	0.077
NOTCH3	Q9UM47-1.2	A1057P	Neutral	0.018
NOTCH3	Q9UM47-1.2	A1057Q	Neutral	0.017
NOTCH3	Q9UM47-1.2	A1057R	Neutral	0.015
NOTCH3	Q9UM47-1.2	A1057S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1057T	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1057V	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1057W	Neutral	0.228
NOTCH3	Q9UM47-1.2	A1057Y	Neutral	0.065
NOTCH3	Q9UM47-1.2	G1058A	Neutral	0.014
NOTCH3	Q9UM47-1.2	G1058C	Pathogenic	0.55
NOTCH3	Q9UM47-1.2	G1058D	Neutral	0.055
NOTCH3	Q9UM47-1.2	G1058E	Neutral	0.197
NOTCH3	Q9UM47-1.2	G1058F	Pathogenic	0.505
NOTCH3	Q9UM47-1.2	G1058H	Neutral	0.191
NOTCH3	Q9UM47-1.2	G1058I	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G1058K	Neutral	0.182
NOTCH3	Q9UM47-1.2	G1058L	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G1058M	Pathogenic	0.514
NOTCH3	Q9UM47-1.2	G1058N	Neutral	0.012
NOTCH3	Q9UM47-1.2	G1058P	Neutral	0.209
NOTCH3	Q9UM47-1.2	G1058Q	Neutral	0.193
NOTCH3	Q9UM47-1.2	G1058R	Neutral	0.175
NOTCH3	Q9UM47-1.2	G1058S	Neutral	0.013
NOTCH3	Q9UM47-1.2	G1058T	Neutral	0.206
NOTCH3	Q9UM47-1.2	G1058V	Pathogenic	0.532
NOTCH3	Q9UM47-1.2	G1058W	Neutral	0.168
NOTCH3	Q9UM47-1.2	G1058Y	Neutral	0.497
NOTCH3	Q9UM47-1.2	G1059A	Neutral	0.24
NOTCH3	Q9UM47-1.2	G1059C	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	G1059D	Pathogenic	0.568
NOTCH3	Q9UM47-1.2	G1059E	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G1059F	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1059H	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	G1059I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1059K	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G1059L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1059M	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G1059N	Neutral	0.22
NOTCH3	Q9UM47-1.2	G1059P	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	G1059Q	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	G1059R	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	G1059S	Neutral	0.235
NOTCH3	Q9UM47-1.2	G1059T	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	G1059V	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G1059W	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	G1059Y	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	Q1060A	Neutral	0.04
NOTCH3	Q9UM47-1.2	Q1060C	Neutral	0.486
NOTCH3	Q9UM47-1.2	Q1060D	Neutral	0.01
NOTCH3	Q9UM47-1.2	Q1060E	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1060F	Neutral	0.494
NOTCH3	Q9UM47-1.2	Q1060G	Neutral	0.151
NOTCH3	Q9UM47-1.2	Q1060H	Neutral	0.011
NOTCH3	Q9UM47-1.2	Q1060I	Pathogenic	0.505
NOTCH3	Q9UM47-1.2	Q1060K	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q1060L	Neutral	0.183
NOTCH3	Q9UM47-1.2	Q1060M	Neutral	0.011
NOTCH3	Q9UM47-1.2	Q1060N	Neutral	0.01
NOTCH3	Q9UM47-1.2	Q1060P	Neutral	0.044
NOTCH3	Q9UM47-1.2	Q1060R	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q1060S	Neutral	0.009
NOTCH3	Q9UM47-1.2	Q1060T	Neutral	0.044
NOTCH3	Q9UM47-1.2	Q1060V	Neutral	0.183
NOTCH3	Q9UM47-1.2	Q1060W	Neutral	0.162
NOTCH3	Q9UM47-1.2	Q1060Y	Neutral	0.044
NOTCH3	Q9UM47-1.2	C1061A	Pathogenic	0.512
NOTCH3	Q9UM47-1.2	C1061D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1061E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1061F	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	C1061G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1061H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1061I	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C1061K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1061L	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C1061M	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C1061N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1061P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1061Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1061R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1061S	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	C1061T	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C1061V	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C1061W	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	C1061Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	V1062A	Neutral	0.041
NOTCH3	Q9UM47-1.2	V1062C	Neutral	0.172
NOTCH3	Q9UM47-1.2	V1062D	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	V1062E	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	V1062F	Neutral	0.167
NOTCH3	Q9UM47-1.2	V1062G	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	V1062H	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	V1062I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V1062K	Neutral	0.48
NOTCH3	Q9UM47-1.2	V1062L	Neutral	0.01
NOTCH3	Q9UM47-1.2	V1062M	Neutral	0.01
NOTCH3	Q9UM47-1.2	V1062N	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	V1062P	Neutral	0.491
NOTCH3	Q9UM47-1.2	V1062Q	Neutral	0.498
NOTCH3	Q9UM47-1.2	V1062R	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	V1062S	Neutral	0.476
NOTCH3	Q9UM47-1.2	V1062T	Neutral	0.045
NOTCH3	Q9UM47-1.2	V1062W	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	V1062Y	Neutral	0.163
NOTCH3	Q9UM47-1.2	D1063A	Pathogenic	0.615
NOTCH3	Q9UM47-1.2	D1063C	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	D1063E	Neutral	0.004
NOTCH3	Q9UM47-1.2	D1063F	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	D1063G	Neutral	0.246
NOTCH3	Q9UM47-1.2	D1063H	Neutral	0.258
NOTCH3	Q9UM47-1.2	D1063I	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	D1063K	Neutral	0.244
NOTCH3	Q9UM47-1.2	D1063L	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	D1063M	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	D1063N	Neutral	0.018
NOTCH3	Q9UM47-1.2	D1063P	Neutral	0.278
NOTCH3	Q9UM47-1.2	D1063Q	Neutral	0.072
NOTCH3	Q9UM47-1.2	D1063R	Pathogenic	0.583
NOTCH3	Q9UM47-1.2	D1063S	Neutral	0.073
NOTCH3	Q9UM47-1.2	D1063T	Neutral	0.277
NOTCH3	Q9UM47-1.2	D1063V	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	D1063W	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	D1063Y	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	E1064A	Neutral	0.007
NOTCH3	Q9UM47-1.2	E1064C	Neutral	0.434
NOTCH3	Q9UM47-1.2	E1064D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1064F	Neutral	0.144
NOTCH3	Q9UM47-1.2	E1064G	Neutral	0.031
NOTCH3	Q9UM47-1.2	E1064H	Neutral	0.002
NOTCH3	Q9UM47-1.2	E1064I	Neutral	0.149
NOTCH3	Q9UM47-1.2	E1064K	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1064L	Neutral	0.149
NOTCH3	Q9UM47-1.2	E1064M	Neutral	0.037
NOTCH3	Q9UM47-1.2	E1064N	Neutral	0.002
NOTCH3	Q9UM47-1.2	E1064P	Neutral	0.008
NOTCH3	Q9UM47-1.2	E1064Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1064R	Neutral	0.002
NOTCH3	Q9UM47-1.2	E1064S	Neutral	0.002
NOTCH3	Q9UM47-1.2	E1064T	Neutral	0.008
NOTCH3	Q9UM47-1.2	E1064V	Neutral	0.038
NOTCH3	Q9UM47-1.2	E1064W	Neutral	0.131
NOTCH3	Q9UM47-1.2	E1064Y	Neutral	0.034
NOTCH3	Q9UM47-1.2	D1065A	Neutral	0.162
NOTCH3	Q9UM47-1.2	D1065C	Neutral	0.488
NOTCH3	Q9UM47-1.2	D1065E	Neutral	0.0
NOTCH3	Q9UM47-1.2	D1065F	Neutral	0.452
NOTCH3	Q9UM47-1.2	D1065G	Neutral	0.038
NOTCH3	Q9UM47-1.2	D1065H	Neutral	0.04
NOTCH3	Q9UM47-1.2	D1065I	Neutral	0.462
NOTCH3	Q9UM47-1.2	D1065K	Neutral	0.038
NOTCH3	Q9UM47-1.2	D1065L	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	D1065M	Neutral	0.461
NOTCH3	Q9UM47-1.2	D1065N	Neutral	0.002
NOTCH3	Q9UM47-1.2	D1065P	Neutral	0.044
NOTCH3	Q9UM47-1.2	D1065Q	Neutral	0.009
NOTCH3	Q9UM47-1.2	D1065R	Neutral	0.144
NOTCH3	Q9UM47-1.2	D1065S	Neutral	0.009
NOTCH3	Q9UM47-1.2	D1065T	Neutral	0.044
NOTCH3	Q9UM47-1.2	D1065V	Neutral	0.479
NOTCH3	Q9UM47-1.2	D1065W	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	D1065Y	Neutral	0.444
NOTCH3	Q9UM47-1.2	S1066A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1066C	Neutral	0.029
NOTCH3	Q9UM47-1.2	S1066D	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1066E	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1066F	Neutral	0.103
NOTCH3	Q9UM47-1.2	S1066G	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1066H	Neutral	0.026
NOTCH3	Q9UM47-1.2	S1066I	Neutral	0.107
NOTCH3	Q9UM47-1.2	S1066K	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1066L	Neutral	0.107
NOTCH3	Q9UM47-1.2	S1066M	Neutral	0.025
NOTCH3	Q9UM47-1.2	S1066N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1066P	Neutral	0.029
NOTCH3	Q9UM47-1.2	S1066Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1066R	Neutral	0.023
NOTCH3	Q9UM47-1.2	S1066T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1066V	Neutral	0.113
NOTCH3	Q9UM47-1.2	S1066W	Neutral	0.319
NOTCH3	Q9UM47-1.2	S1066Y	Neutral	0.1
NOTCH3	Q9UM47-1.2	S1067A	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1067C	Neutral	0.098
NOTCH3	Q9UM47-1.2	S1067D	Neutral	0.023
NOTCH3	Q9UM47-1.2	S1067E	Neutral	0.021
NOTCH3	Q9UM47-1.2	S1067F	Neutral	0.292
NOTCH3	Q9UM47-1.2	S1067G	Neutral	0.022
NOTCH3	Q9UM47-1.2	S1067H	Neutral	0.087
NOTCH3	Q9UM47-1.2	S1067I	Neutral	0.301
NOTCH3	Q9UM47-1.2	S1067K	Neutral	0.019
NOTCH3	Q9UM47-1.2	S1067L	Neutral	0.301
NOTCH3	Q9UM47-1.2	S1067M	Neutral	0.086
NOTCH3	Q9UM47-1.2	S1067N	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1067P	Neutral	0.097
NOTCH3	Q9UM47-1.2	S1067Q	Neutral	0.021
NOTCH3	Q9UM47-1.2	S1067R	Neutral	0.079
NOTCH3	Q9UM47-1.2	S1067T	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1067V	Neutral	0.316
NOTCH3	Q9UM47-1.2	S1067W	Pathogenic	0.629
NOTCH3	Q9UM47-1.2	S1067Y	Neutral	0.286
NOTCH3	Q9UM47-1.2	H1068A	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	H1068C	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1068D	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	H1068E	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	H1068F	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	H1068G	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	H1068I	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1068K	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	H1068L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1068M	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	H1068N	Neutral	0.358
NOTCH3	Q9UM47-1.2	H1068P	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	H1068Q	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	H1068R	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	H1068S	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	H1068T	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	H1068V	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1068W	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	H1068Y	Neutral	0.109
NOTCH3	Q9UM47-1.2	Y1069A	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	Y1069C	Pathogenic	0.649
NOTCH3	Q9UM47-1.2	Y1069D	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	Y1069E	Pathogenic	0.672
NOTCH3	Q9UM47-1.2	Y1069F	Neutral	0.001
NOTCH3	Q9UM47-1.2	Y1069G	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	Y1069H	Neutral	0.005
NOTCH3	Q9UM47-1.2	Y1069I	Neutral	0.322
NOTCH3	Q9UM47-1.2	Y1069K	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	Y1069L	Neutral	0.321
NOTCH3	Q9UM47-1.2	Y1069M	Neutral	0.321
NOTCH3	Q9UM47-1.2	Y1069N	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	Y1069P	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	Y1069Q	Neutral	0.314
NOTCH3	Q9UM47-1.2	Y1069R	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	Y1069S	Pathogenic	0.64
NOTCH3	Q9UM47-1.2	Y1069T	Pathogenic	0.657
NOTCH3	Q9UM47-1.2	Y1069V	Neutral	0.305
NOTCH3	Q9UM47-1.2	Y1069W	Neutral	0.005
NOTCH3	Q9UM47-1.2	C1070A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C1070D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1070E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1070F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C1070G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1070H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1070I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1070K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1070L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1070M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C1070N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1070P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1070Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1070R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1070S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C1070T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C1070V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C1070W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C1070Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	V1071A	Neutral	0.003
NOTCH3	Q9UM47-1.2	V1071C	Neutral	0.016
NOTCH3	Q9UM47-1.2	V1071D	Neutral	0.258
NOTCH3	Q9UM47-1.2	V1071E	Neutral	0.073
NOTCH3	Q9UM47-1.2	V1071F	Neutral	0.015
NOTCH3	Q9UM47-1.2	V1071G	Neutral	0.226
NOTCH3	Q9UM47-1.2	V1071H	Neutral	0.257
NOTCH3	Q9UM47-1.2	V1071I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V1071K	Neutral	0.067
NOTCH3	Q9UM47-1.2	V1071L	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1071M	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1071N	Neutral	0.261
NOTCH3	Q9UM47-1.2	V1071P	Neutral	0.07
NOTCH3	Q9UM47-1.2	V1071Q	Neutral	0.072
NOTCH3	Q9UM47-1.2	V1071R	Neutral	0.237
NOTCH3	Q9UM47-1.2	V1071S	Neutral	0.066
NOTCH3	Q9UM47-1.2	V1071T	Neutral	0.004
NOTCH3	Q9UM47-1.2	V1071W	Neutral	0.225
NOTCH3	Q9UM47-1.2	V1071Y	Neutral	0.015
NOTCH3	Q9UM47-1.2	C1072A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C1072D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1072E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1072F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C1072G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1072H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1072I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1072K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1072L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1072M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C1072N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1072P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1072Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1072R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1072S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C1072T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C1072V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C1072W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C1072Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	P1073A	Neutral	0.09
NOTCH3	Q9UM47-1.2	P1073C	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	P1073D	Neutral	0.098
NOTCH3	Q9UM47-1.2	P1073E	Neutral	0.092
NOTCH3	Q9UM47-1.2	P1073F	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	P1073G	Neutral	0.296
NOTCH3	Q9UM47-1.2	P1073H	Neutral	0.307
NOTCH3	Q9UM47-1.2	P1073I	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	P1073K	Neutral	0.084
NOTCH3	Q9UM47-1.2	P1073L	Pathogenic	0.664
NOTCH3	Q9UM47-1.2	P1073M	Neutral	0.302
NOTCH3	Q9UM47-1.2	P1073N	Neutral	0.327
NOTCH3	Q9UM47-1.2	P1073Q	Neutral	0.09
NOTCH3	Q9UM47-1.2	P1073R	Neutral	0.285
NOTCH3	Q9UM47-1.2	P1073S	Neutral	0.092
NOTCH3	Q9UM47-1.2	P1073T	Neutral	0.097
NOTCH3	Q9UM47-1.2	P1073V	Neutral	0.318
NOTCH3	Q9UM47-1.2	P1073W	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	P1073Y	Pathogenic	0.648
NOTCH3	Q9UM47-1.2	E1074A	Neutral	0.019
NOTCH3	Q9UM47-1.2	E1074C	Pathogenic	0.663
NOTCH3	Q9UM47-1.2	E1074D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1074F	Neutral	0.3
NOTCH3	Q9UM47-1.2	E1074G	Neutral	0.075
NOTCH3	Q9UM47-1.2	E1074H	Neutral	0.005
NOTCH3	Q9UM47-1.2	E1074I	Neutral	0.309
NOTCH3	Q9UM47-1.2	E1074K	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1074L	Neutral	0.309
NOTCH3	Q9UM47-1.2	E1074M	Neutral	0.089
NOTCH3	Q9UM47-1.2	E1074N	Neutral	0.005
NOTCH3	Q9UM47-1.2	E1074P	Neutral	0.021
NOTCH3	Q9UM47-1.2	E1074Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1074R	Neutral	0.004
NOTCH3	Q9UM47-1.2	E1074S	Neutral	0.004
NOTCH3	Q9UM47-1.2	E1074T	Neutral	0.021
NOTCH3	Q9UM47-1.2	E1074V	Neutral	0.093
NOTCH3	Q9UM47-1.2	E1074W	Neutral	0.279
NOTCH3	Q9UM47-1.2	E1074Y	Neutral	0.084
NOTCH3	Q9UM47-1.2	G1075A	Neutral	0.168
NOTCH3	Q9UM47-1.2	G1075C	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	G1075D	Neutral	0.457
NOTCH3	Q9UM47-1.2	G1075E	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	G1075F	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	G1075H	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	G1075I	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	G1075K	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	G1075L	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	G1075M	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	G1075N	Neutral	0.153
NOTCH3	Q9UM47-1.2	G1075P	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	G1075Q	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	G1075R	Pathogenic	0.755
NOTCH3	Q9UM47-1.2	G1075S	Neutral	0.164
NOTCH3	Q9UM47-1.2	G1075T	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	G1075V	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	G1075W	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	G1075Y	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	R1076A	Neutral	0.062
NOTCH3	Q9UM47-1.2	R1076C	Pathogenic	0.598
NOTCH3	Q9UM47-1.2	R1076D	Neutral	0.247
NOTCH3	Q9UM47-1.2	R1076E	Neutral	0.017
NOTCH3	Q9UM47-1.2	R1076F	Pathogenic	0.644
NOTCH3	Q9UM47-1.2	R1076G	Neutral	0.219
NOTCH3	Q9UM47-1.2	R1076H	Neutral	0.017
NOTCH3	Q9UM47-1.2	R1076I	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	R1076K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1076L	Neutral	0.276
NOTCH3	Q9UM47-1.2	R1076M	Neutral	0.077
NOTCH3	Q9UM47-1.2	R1076N	Neutral	0.016
NOTCH3	Q9UM47-1.2	R1076P	Neutral	0.249
NOTCH3	Q9UM47-1.2	R1076Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	R1076S	Neutral	0.063
NOTCH3	Q9UM47-1.2	R1076T	Neutral	0.068
NOTCH3	Q9UM47-1.2	R1076V	Pathogenic	0.616
NOTCH3	Q9UM47-1.2	R1076W	Pathogenic	0.643
NOTCH3	Q9UM47-1.2	R1076Y	Neutral	0.288
NOTCH3	Q9UM47-1.2	T1077A	Neutral	0.36
NOTCH3	Q9UM47-1.2	T1077C	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	T1077D	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	T1077E	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	T1077F	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	T1077G	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	T1077H	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	T1077I	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	T1077K	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	T1077L	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	T1077M	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	T1077N	Neutral	0.382
NOTCH3	Q9UM47-1.2	T1077P	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	T1077Q	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	T1077R	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	T1077S	Neutral	0.112
NOTCH3	Q9UM47-1.2	T1077V	Neutral	0.374
NOTCH3	Q9UM47-1.2	T1077W	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	T1077Y	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	G1078A	Neutral	0.242
NOTCH3	Q9UM47-1.2	G1078C	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	G1078D	Pathogenic	0.571
NOTCH3	Q9UM47-1.2	G1078E	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	G1078F	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1078H	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	G1078I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1078K	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	G1078L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1078M	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G1078N	Neutral	0.222
NOTCH3	Q9UM47-1.2	G1078P	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	G1078Q	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G1078R	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	G1078S	Neutral	0.237
NOTCH3	Q9UM47-1.2	G1078T	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	G1078V	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G1078W	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	G1078Y	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	S1079A	Neutral	0.112
NOTCH3	Q9UM47-1.2	S1079C	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	S1079D	Neutral	0.354
NOTCH3	Q9UM47-1.2	S1079E	Neutral	0.338
NOTCH3	Q9UM47-1.2	S1079F	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	S1079G	Neutral	0.347
NOTCH3	Q9UM47-1.2	S1079H	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	S1079I	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	S1079K	Neutral	0.317
NOTCH3	Q9UM47-1.2	S1079L	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	S1079M	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	S1079N	Neutral	0.106
NOTCH3	Q9UM47-1.2	S1079P	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	S1079Q	Neutral	0.333
NOTCH3	Q9UM47-1.2	S1079R	Pathogenic	0.668
NOTCH3	Q9UM47-1.2	S1079T	Neutral	0.106
NOTCH3	Q9UM47-1.2	S1079V	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	S1079W	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	S1079Y	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	H1080A	Pathogenic	0.506
NOTCH3	Q9UM47-1.2	H1080C	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	H1080D	Neutral	0.199
NOTCH3	Q9UM47-1.2	H1080E	Neutral	0.055
NOTCH3	Q9UM47-1.2	H1080F	Neutral	0.206
NOTCH3	Q9UM47-1.2	H1080G	Neutral	0.487
NOTCH3	Q9UM47-1.2	H1080I	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	H1080K	Neutral	0.205
NOTCH3	Q9UM47-1.2	H1080L	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	H1080M	Pathogenic	0.551
NOTCH3	Q9UM47-1.2	H1080N	Neutral	0.012
NOTCH3	Q9UM47-1.2	H1080P	Pathogenic	0.529
NOTCH3	Q9UM47-1.2	H1080Q	Neutral	0.056
NOTCH3	Q9UM47-1.2	H1080R	Neutral	0.051
NOTCH3	Q9UM47-1.2	H1080S	Neutral	0.187
NOTCH3	Q9UM47-1.2	H1080T	Pathogenic	0.53
NOTCH3	Q9UM47-1.2	H1080V	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	H1080W	Pathogenic	0.515
NOTCH3	Q9UM47-1.2	H1080Y	Neutral	0.003
NOTCH3	Q9UM47-1.2	C1081A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C1081D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1081E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1081F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C1081G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1081H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1081I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1081K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1081L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1081M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C1081N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1081P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1081Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1081R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1081S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C1081T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C1081V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C1081W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C1081Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	E1082A	Pathogenic	0.618
NOTCH3	Q9UM47-1.2	E1082C	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	E1082D	Neutral	0.018
NOTCH3	Q9UM47-1.2	E1082F	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	E1082G	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	E1082H	Neutral	0.287
NOTCH3	Q9UM47-1.2	E1082I	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	E1082K	Neutral	0.076
NOTCH3	Q9UM47-1.2	E1082L	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	E1082M	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	E1082N	Neutral	0.283
NOTCH3	Q9UM47-1.2	E1082P	Pathogenic	0.64
NOTCH3	Q9UM47-1.2	E1082Q	Neutral	0.019
NOTCH3	Q9UM47-1.2	E1082R	Neutral	0.264
NOTCH3	Q9UM47-1.2	E1082S	Neutral	0.266
NOTCH3	Q9UM47-1.2	E1082T	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	E1082V	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	E1082W	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	E1082Y	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	Q1083A	Neutral	0.024
NOTCH3	Q9UM47-1.2	Q1083C	Neutral	0.353
NOTCH3	Q9UM47-1.2	Q1083D	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q1083E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1083F	Neutral	0.36
NOTCH3	Q9UM47-1.2	Q1083G	Neutral	0.093
NOTCH3	Q9UM47-1.2	Q1083H	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q1083I	Neutral	0.37
NOTCH3	Q9UM47-1.2	Q1083K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1083L	Neutral	0.114
NOTCH3	Q9UM47-1.2	Q1083M	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q1083N	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q1083P	Neutral	0.026
NOTCH3	Q9UM47-1.2	Q1083R	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1083S	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q1083T	Neutral	0.026
NOTCH3	Q9UM47-1.2	Q1083V	Neutral	0.114
NOTCH3	Q9UM47-1.2	Q1083W	Neutral	0.1
NOTCH3	Q9UM47-1.2	Q1083Y	Neutral	0.026
NOTCH3	Q9UM47-1.2	E1084A	Neutral	0.095
NOTCH3	Q9UM47-1.2	E1084C	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	E1084D	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1084F	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	E1084G	Neutral	0.307
NOTCH3	Q9UM47-1.2	E1084H	Neutral	0.025
NOTCH3	Q9UM47-1.2	E1084I	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	E1084K	Neutral	0.005
NOTCH3	Q9UM47-1.2	E1084L	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	E1084M	Neutral	0.348
NOTCH3	Q9UM47-1.2	E1084N	Neutral	0.025
NOTCH3	Q9UM47-1.2	E1084P	Neutral	0.103
NOTCH3	Q9UM47-1.2	E1084Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1084R	Neutral	0.023
NOTCH3	Q9UM47-1.2	E1084S	Neutral	0.023
NOTCH3	Q9UM47-1.2	E1084T	Neutral	0.104
NOTCH3	Q9UM47-1.2	E1084V	Neutral	0.357
NOTCH3	Q9UM47-1.2	E1084W	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	E1084Y	Neutral	0.333
NOTCH3	Q9UM47-1.2	V1085A	Neutral	0.149
NOTCH3	Q9UM47-1.2	V1085C	Neutral	0.46
NOTCH3	Q9UM47-1.2	V1085D	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	V1085E	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	V1085F	Neutral	0.45
NOTCH3	Q9UM47-1.2	V1085G	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	V1085H	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	V1085I	Neutral	0.002
NOTCH3	Q9UM47-1.2	V1085K	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	V1085L	Neutral	0.04
NOTCH3	Q9UM47-1.2	V1085M	Neutral	0.039
NOTCH3	Q9UM47-1.2	V1085N	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	V1085P	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	V1085Q	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	V1085R	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	V1085S	Pathogenic	0.788
NOTCH3	Q9UM47-1.2	V1085T	Neutral	0.162
NOTCH3	Q9UM47-1.2	V1085W	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	V1085Y	Neutral	0.444
NOTCH3	Q9UM47-1.2	D1086A	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	D1086C	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	D1086E	Neutral	0.015
NOTCH3	Q9UM47-1.2	D1086F	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	D1086G	Pathogenic	0.572
NOTCH3	Q9UM47-1.2	D1086H	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	D1086I	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	D1086K	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	D1086L	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	D1086M	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	D1086N	Neutral	0.069
NOTCH3	Q9UM47-1.2	D1086P	Pathogenic	0.612
NOTCH3	Q9UM47-1.2	D1086Q	Neutral	0.24
NOTCH3	Q9UM47-1.2	D1086R	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	D1086S	Neutral	0.244
NOTCH3	Q9UM47-1.2	D1086T	Pathogenic	0.61
NOTCH3	Q9UM47-1.2	D1086V	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	D1086W	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	D1086Y	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	P1087A	Neutral	0.034
NOTCH3	Q9UM47-1.2	P1087C	Neutral	0.441
NOTCH3	Q9UM47-1.2	P1087D	Neutral	0.037
NOTCH3	Q9UM47-1.2	P1087E	Neutral	0.035
NOTCH3	Q9UM47-1.2	P1087F	Pathogenic	0.755
NOTCH3	Q9UM47-1.2	P1087G	Neutral	0.131
NOTCH3	Q9UM47-1.2	P1087H	Neutral	0.137
NOTCH3	Q9UM47-1.2	P1087I	Neutral	0.414
NOTCH3	Q9UM47-1.2	P1087K	Neutral	0.032
NOTCH3	Q9UM47-1.2	P1087L	Neutral	0.414
NOTCH3	Q9UM47-1.2	P1087M	Neutral	0.134
NOTCH3	Q9UM47-1.2	P1087N	Neutral	0.148
NOTCH3	Q9UM47-1.2	P1087Q	Neutral	0.034
NOTCH3	Q9UM47-1.2	P1087R	Neutral	0.125
NOTCH3	Q9UM47-1.2	P1087S	Neutral	0.035
NOTCH3	Q9UM47-1.2	P1087T	Neutral	0.037
NOTCH3	Q9UM47-1.2	P1087V	Neutral	0.143
NOTCH3	Q9UM47-1.2	P1087W	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	P1087Y	Neutral	0.397
NOTCH3	Q9UM47-1.2	C1088A	Neutral	0.499
NOTCH3	Q9UM47-1.2	C1088D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1088E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1088F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	C1088G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1088H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1088I	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1088K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1088L	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1088M	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1088N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1088P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1088Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1088R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1088S	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C1088T	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C1088V	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1088W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C1088Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	L1089A	Neutral	0.008
NOTCH3	Q9UM47-1.2	L1089C	Neutral	0.009
NOTCH3	Q9UM47-1.2	L1089D	Neutral	0.471
NOTCH3	Q9UM47-1.2	L1089E	Neutral	0.173
NOTCH3	Q9UM47-1.2	L1089F	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1089G	Neutral	0.428
NOTCH3	Q9UM47-1.2	L1089H	Neutral	0.177
NOTCH3	Q9UM47-1.2	L1089I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1089K	Neutral	0.045
NOTCH3	Q9UM47-1.2	L1089M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1089N	Neutral	0.166
NOTCH3	Q9UM47-1.2	L1089P	Neutral	0.161
NOTCH3	Q9UM47-1.2	L1089Q	Neutral	0.045
NOTCH3	Q9UM47-1.2	L1089R	Neutral	0.043
NOTCH3	Q9UM47-1.2	L1089S	Neutral	0.038
NOTCH3	Q9UM47-1.2	L1089T	Neutral	0.009
NOTCH3	Q9UM47-1.2	L1089V	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1089W	Neutral	0.04
NOTCH3	Q9UM47-1.2	L1089Y	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1090C	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1090D	Neutral	0.105
NOTCH3	Q9UM47-1.2	A1090E	Neutral	0.023
NOTCH3	Q9UM47-1.2	A1090F	Neutral	0.09
NOTCH3	Q9UM47-1.2	A1090G	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1090H	Neutral	0.095
NOTCH3	Q9UM47-1.2	A1090I	Neutral	0.022
NOTCH3	Q9UM47-1.2	A1090K	Neutral	0.021
NOTCH3	Q9UM47-1.2	A1090L	Neutral	0.022
NOTCH3	Q9UM47-1.2	A1090M	Neutral	0.022
NOTCH3	Q9UM47-1.2	A1090N	Neutral	0.103
NOTCH3	Q9UM47-1.2	A1090P	Neutral	0.025
NOTCH3	Q9UM47-1.2	A1090Q	Neutral	0.023
NOTCH3	Q9UM47-1.2	A1090R	Neutral	0.02
NOTCH3	Q9UM47-1.2	A1090S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1090T	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1090V	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1090W	Neutral	0.289
NOTCH3	Q9UM47-1.2	A1090Y	Neutral	0.088
NOTCH3	Q9UM47-1.2	Q1091A	Neutral	0.035
NOTCH3	Q9UM47-1.2	Q1091C	Neutral	0.447
NOTCH3	Q9UM47-1.2	Q1091D	Neutral	0.009
NOTCH3	Q9UM47-1.2	Q1091E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1091F	Neutral	0.455
NOTCH3	Q9UM47-1.2	Q1091G	Neutral	0.132
NOTCH3	Q9UM47-1.2	Q1091H	Neutral	0.009
NOTCH3	Q9UM47-1.2	Q1091I	Neutral	0.466
NOTCH3	Q9UM47-1.2	Q1091K	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q1091L	Neutral	0.161
NOTCH3	Q9UM47-1.2	Q1091M	Neutral	0.009
NOTCH3	Q9UM47-1.2	Q1091N	Neutral	0.009
NOTCH3	Q9UM47-1.2	Q1091P	Neutral	0.038
NOTCH3	Q9UM47-1.2	Q1091R	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q1091S	Neutral	0.008
NOTCH3	Q9UM47-1.2	Q1091T	Neutral	0.038
NOTCH3	Q9UM47-1.2	Q1091V	Neutral	0.161
NOTCH3	Q9UM47-1.2	Q1091W	Neutral	0.142
NOTCH3	Q9UM47-1.2	Q1091Y	Neutral	0.038
NOTCH3	Q9UM47-1.2	P1092A	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	P1092C	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	P1092D	Pathogenic	0.701
NOTCH3	Q9UM47-1.2	P1092E	Pathogenic	0.686
NOTCH3	Q9UM47-1.2	P1092F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P1092G	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	P1092H	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	P1092I	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	P1092K	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	P1092L	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	P1092M	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	P1092N	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	P1092Q	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	P1092R	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	P1092S	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	P1092T	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	P1092V	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	P1092W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P1092Y	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	C1093A	Neutral	0.499
NOTCH3	Q9UM47-1.2	C1093D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1093E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1093F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	C1093G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1093H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1093I	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1093K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1093L	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1093M	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1093N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1093P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1093Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1093R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1093S	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C1093T	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C1093V	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1093W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C1093Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	Q1094A	Pathogenic	0.613
NOTCH3	Q9UM47-1.2	Q1094C	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	Q1094D	Neutral	0.276
NOTCH3	Q9UM47-1.2	Q1094E	Neutral	0.019
NOTCH3	Q9UM47-1.2	Q1094F	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	Q1094G	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	Q1094H	Neutral	0.291
NOTCH3	Q9UM47-1.2	Q1094I	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	Q1094K	Neutral	0.078
NOTCH3	Q9UM47-1.2	Q1094L	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	Q1094M	Neutral	0.288
NOTCH3	Q9UM47-1.2	Q1094N	Neutral	0.28
NOTCH3	Q9UM47-1.2	Q1094P	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	Q1094R	Neutral	0.074
NOTCH3	Q9UM47-1.2	Q1094S	Neutral	0.262
NOTCH3	Q9UM47-1.2	Q1094T	Pathogenic	0.636
NOTCH3	Q9UM47-1.2	Q1094V	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	Q1094W	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	Q1094Y	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	H1095A	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	H1095C	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	H1095D	Neutral	0.478
NOTCH3	Q9UM47-1.2	H1095E	Neutral	0.177
NOTCH3	Q9UM47-1.2	H1095F	Neutral	0.489
NOTCH3	Q9UM47-1.2	H1095G	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	H1095I	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	H1095K	Neutral	0.488
NOTCH3	Q9UM47-1.2	H1095L	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	H1095M	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	H1095N	Neutral	0.043
NOTCH3	Q9UM47-1.2	H1095P	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	H1095Q	Neutral	0.179
NOTCH3	Q9UM47-1.2	H1095R	Neutral	0.166
NOTCH3	Q9UM47-1.2	H1095S	Neutral	0.459
NOTCH3	Q9UM47-1.2	H1095T	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	H1095V	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	H1095W	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	H1095Y	Neutral	0.01
NOTCH3	Q9UM47-1.2	G1096A	Neutral	0.219
NOTCH3	Q9UM47-1.2	G1096C	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G1096D	Pathogenic	0.539
NOTCH3	Q9UM47-1.2	G1096E	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	G1096F	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G1096H	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	G1096I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1096K	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	G1096L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1096M	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G1096N	Neutral	0.201
NOTCH3	Q9UM47-1.2	G1096P	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	G1096Q	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G1096R	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	G1096S	Neutral	0.215
NOTCH3	Q9UM47-1.2	G1096T	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	G1096V	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G1096W	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	G1096Y	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	G1097A	Neutral	0.008
NOTCH3	Q9UM47-1.2	G1097C	Neutral	0.411
NOTCH3	Q9UM47-1.2	G1097D	Neutral	0.032
NOTCH3	Q9UM47-1.2	G1097E	Neutral	0.123
NOTCH3	Q9UM47-1.2	G1097F	Neutral	0.368
NOTCH3	Q9UM47-1.2	G1097H	Neutral	0.119
NOTCH3	Q9UM47-1.2	G1097I	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	G1097K	Neutral	0.113
NOTCH3	Q9UM47-1.2	G1097L	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	G1097M	Neutral	0.377
NOTCH3	Q9UM47-1.2	G1097N	Neutral	0.007
NOTCH3	Q9UM47-1.2	G1097P	Neutral	0.131
NOTCH3	Q9UM47-1.2	G1097Q	Neutral	0.12
NOTCH3	Q9UM47-1.2	G1097R	Neutral	0.108
NOTCH3	Q9UM47-1.2	G1097S	Neutral	0.008
NOTCH3	Q9UM47-1.2	G1097T	Neutral	0.129
NOTCH3	Q9UM47-1.2	G1097V	Neutral	0.394
NOTCH3	Q9UM47-1.2	G1097W	Neutral	0.103
NOTCH3	Q9UM47-1.2	G1097Y	Neutral	0.361
NOTCH3	Q9UM47-1.2	T1098A	Neutral	0.357
NOTCH3	Q9UM47-1.2	T1098C	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	T1098D	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	T1098E	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	T1098F	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	T1098G	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	T1098H	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	T1098I	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	T1098K	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	T1098L	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	T1098M	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	T1098N	Neutral	0.379
NOTCH3	Q9UM47-1.2	T1098P	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	T1098Q	Pathogenic	0.721
NOTCH3	Q9UM47-1.2	T1098R	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	T1098S	Neutral	0.111
NOTCH3	Q9UM47-1.2	T1098V	Neutral	0.372
NOTCH3	Q9UM47-1.2	T1098W	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	T1098Y	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	C1099A	Neutral	0.499
NOTCH3	Q9UM47-1.2	C1099D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1099E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1099F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	C1099G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1099H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1099I	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1099K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1099L	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1099M	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1099N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1099P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1099Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1099R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1099S	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C1099T	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C1099V	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1099W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C1099Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	R1100A	Neutral	0.126
NOTCH3	Q9UM47-1.2	R1100C	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	R1100D	Neutral	0.416
NOTCH3	Q9UM47-1.2	R1100E	Neutral	0.036
NOTCH3	Q9UM47-1.2	R1100F	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	R1100G	Neutral	0.378
NOTCH3	Q9UM47-1.2	R1100H	Neutral	0.037
NOTCH3	Q9UM47-1.2	R1100I	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	R1100K	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1100L	Neutral	0.452
NOTCH3	Q9UM47-1.2	R1100M	Neutral	0.153
NOTCH3	Q9UM47-1.2	R1100N	Neutral	0.034
NOTCH3	Q9UM47-1.2	R1100P	Neutral	0.418
NOTCH3	Q9UM47-1.2	R1100Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	R1100S	Neutral	0.128
NOTCH3	Q9UM47-1.2	R1100T	Neutral	0.137
NOTCH3	Q9UM47-1.2	R1100V	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	R1100W	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	R1100Y	Neutral	0.467
NOTCH3	Q9UM47-1.2	G1101A	Neutral	0.007
NOTCH3	Q9UM47-1.2	G1101C	Neutral	0.376
NOTCH3	Q9UM47-1.2	G1101D	Neutral	0.028
NOTCH3	Q9UM47-1.2	G1101E	Neutral	0.108
NOTCH3	Q9UM47-1.2	G1101F	Neutral	0.335
NOTCH3	Q9UM47-1.2	G1101H	Neutral	0.104
NOTCH3	Q9UM47-1.2	G1101I	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	G1101K	Neutral	0.099
NOTCH3	Q9UM47-1.2	G1101L	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	G1101M	Neutral	0.343
NOTCH3	Q9UM47-1.2	G1101N	Neutral	0.006
NOTCH3	Q9UM47-1.2	G1101P	Neutral	0.115
NOTCH3	Q9UM47-1.2	G1101Q	Neutral	0.106
NOTCH3	Q9UM47-1.2	G1101R	Neutral	0.095
NOTCH3	Q9UM47-1.2	G1101S	Neutral	0.007
NOTCH3	Q9UM47-1.2	G1101T	Neutral	0.114
NOTCH3	Q9UM47-1.2	G1101V	Neutral	0.36
NOTCH3	Q9UM47-1.2	G1101W	Neutral	0.091
NOTCH3	Q9UM47-1.2	G1101Y	Neutral	0.328
NOTCH3	Q9UM47-1.2	Y1102A	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	Y1102C	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	Y1102D	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	Y1102E	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	Y1102F	Neutral	0.005
NOTCH3	Q9UM47-1.2	Y1102G	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	Y1102H	Neutral	0.02
NOTCH3	Q9UM47-1.2	Y1102I	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	Y1102K	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	Y1102L	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	Y1102M	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	Y1102N	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	Y1102P	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	Y1102Q	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	Y1102R	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	Y1102S	Pathogenic	0.882
NOTCH3	Q9UM47-1.2	Y1102T	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	Y1102V	Pathogenic	0.648
NOTCH3	Q9UM47-1.2	Y1102W	Neutral	0.02
NOTCH3	Q9UM47-1.2	M1103A	Neutral	0.122
NOTCH3	Q9UM47-1.2	M1103C	Neutral	0.129
NOTCH3	Q9UM47-1.2	M1103D	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	M1103E	Neutral	0.427
NOTCH3	Q9UM47-1.2	M1103F	Neutral	0.035
NOTCH3	Q9UM47-1.2	M1103G	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	M1103H	Neutral	0.434
NOTCH3	Q9UM47-1.2	M1103I	Neutral	0.008
NOTCH3	Q9UM47-1.2	M1103K	Neutral	0.143
NOTCH3	Q9UM47-1.2	M1103L	Neutral	0.002
NOTCH3	Q9UM47-1.2	M1103N	Neutral	0.415
NOTCH3	Q9UM47-1.2	M1103P	Neutral	0.407
NOTCH3	Q9UM47-1.2	M1103Q	Neutral	0.035
NOTCH3	Q9UM47-1.2	M1103R	Neutral	0.137
NOTCH3	Q9UM47-1.2	M1103S	Neutral	0.124
NOTCH3	Q9UM47-1.2	M1103T	Neutral	0.133
NOTCH3	Q9UM47-1.2	M1103V	Neutral	0.008
NOTCH3	Q9UM47-1.2	M1103W	Neutral	0.129
NOTCH3	Q9UM47-1.2	M1103Y	Neutral	0.138
NOTCH3	Q9UM47-1.2	G1104A	Neutral	0.201
NOTCH3	Q9UM47-1.2	G1104C	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G1104D	Pathogenic	0.512
NOTCH3	Q9UM47-1.2	G1104E	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	G1104F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	G1104H	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	G1104I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G1104K	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	G1104L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G1104M	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	G1104N	Neutral	0.184
NOTCH3	Q9UM47-1.2	G1104P	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	G1104Q	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	G1104R	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	G1104S	Neutral	0.197
NOTCH3	Q9UM47-1.2	G1104T	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	G1104V	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G1104W	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	G1104Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	G1105A	Neutral	0.082
NOTCH3	Q9UM47-1.2	G1105C	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	G1105D	Neutral	0.271
NOTCH3	Q9UM47-1.2	G1105E	Pathogenic	0.612
NOTCH3	Q9UM47-1.2	G1105F	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	G1105H	Pathogenic	0.603
NOTCH3	Q9UM47-1.2	G1105I	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	G1105K	Pathogenic	0.588
NOTCH3	Q9UM47-1.2	G1105L	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	G1105M	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	G1105N	Neutral	0.074
NOTCH3	Q9UM47-1.2	G1105P	Pathogenic	0.629
NOTCH3	Q9UM47-1.2	G1105Q	Pathogenic	0.606
NOTCH3	Q9UM47-1.2	G1105R	Pathogenic	0.576
NOTCH3	Q9UM47-1.2	G1105S	Neutral	0.08
NOTCH3	Q9UM47-1.2	G1105T	Pathogenic	0.626
NOTCH3	Q9UM47-1.2	G1105V	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	G1105W	Pathogenic	0.565
NOTCH3	Q9UM47-1.2	G1105Y	Pathogenic	0.864
NOTCH3	Q9UM47-1.2	Y1106A	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	Y1106C	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	Y1106D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	Y1106E	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	Y1106F	Neutral	0.031
NOTCH3	Q9UM47-1.2	Y1106G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	Y1106H	Neutral	0.121
NOTCH3	Q9UM47-1.2	Y1106I	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	Y1106K	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	Y1106L	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	Y1106M	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	Y1106N	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	Y1106P	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	Y1106Q	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	Y1106R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	Y1106S	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	Y1106T	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	Y1106V	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	Y1106W	Neutral	0.122
NOTCH3	Q9UM47-1.2	M1107A	Neutral	0.022
NOTCH3	Q9UM47-1.2	M1107C	Neutral	0.024
NOTCH3	Q9UM47-1.2	M1107D	Neutral	0.343
NOTCH3	Q9UM47-1.2	M1107E	Neutral	0.109
NOTCH3	Q9UM47-1.2	M1107F	Neutral	0.006
NOTCH3	Q9UM47-1.2	M1107G	Neutral	0.305
NOTCH3	Q9UM47-1.2	M1107H	Neutral	0.112
NOTCH3	Q9UM47-1.2	M1107I	Neutral	0.001
NOTCH3	Q9UM47-1.2	M1107K	Neutral	0.027
NOTCH3	Q9UM47-1.2	M1107L	Neutral	0.0
NOTCH3	Q9UM47-1.2	M1107N	Neutral	0.104
NOTCH3	Q9UM47-1.2	M1107P	Neutral	0.101
NOTCH3	Q9UM47-1.2	M1107Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	M1107R	Neutral	0.025
NOTCH3	Q9UM47-1.2	M1107S	Neutral	0.023
NOTCH3	Q9UM47-1.2	M1107T	Neutral	0.025
NOTCH3	Q9UM47-1.2	M1107V	Neutral	0.001
NOTCH3	Q9UM47-1.2	M1107W	Neutral	0.024
NOTCH3	Q9UM47-1.2	M1107Y	Neutral	0.026
NOTCH3	Q9UM47-1.2	C1108A	Neutral	0.499
NOTCH3	Q9UM47-1.2	C1108D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1108E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1108F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	C1108G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1108H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1108I	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1108K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1108L	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1108M	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1108N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1108P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1108Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1108R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1108S	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C1108T	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C1108V	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1108W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C1108Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	E1109A	Neutral	0.274
NOTCH3	Q9UM47-1.2	E1109C	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	E1109D	Neutral	0.004
NOTCH3	Q9UM47-1.2	E1109F	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	E1109G	Pathogenic	0.615
NOTCH3	Q9UM47-1.2	E1109H	Neutral	0.086
NOTCH3	Q9UM47-1.2	E1109I	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	E1109K	Neutral	0.019
NOTCH3	Q9UM47-1.2	E1109L	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	E1109M	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	E1109N	Neutral	0.084
NOTCH3	Q9UM47-1.2	E1109P	Neutral	0.293
NOTCH3	Q9UM47-1.2	E1109Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	E1109R	Neutral	0.077
NOTCH3	Q9UM47-1.2	E1109S	Neutral	0.078
NOTCH3	Q9UM47-1.2	E1109T	Neutral	0.295
NOTCH3	Q9UM47-1.2	E1109V	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	E1109W	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	E1109Y	Pathogenic	0.643
NOTCH3	Q9UM47-1.2	C1110A	Pathogenic	0.509
NOTCH3	Q9UM47-1.2	C1110D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1110E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1110F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	C1110G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1110H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1110I	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C1110K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1110L	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C1110M	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C1110N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1110P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1110Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1110R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1110S	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C1110T	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	C1110V	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	C1110W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C1110Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	L1111A	Neutral	0.003
NOTCH3	Q9UM47-1.2	L1111C	Neutral	0.003
NOTCH3	Q9UM47-1.2	L1111D	Neutral	0.218
NOTCH3	Q9UM47-1.2	L1111E	Neutral	0.062
NOTCH3	Q9UM47-1.2	L1111F	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1111G	Neutral	0.19
NOTCH3	Q9UM47-1.2	L1111H	Neutral	0.063
NOTCH3	Q9UM47-1.2	L1111I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1111K	Neutral	0.014
NOTCH3	Q9UM47-1.2	L1111M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1111N	Neutral	0.059
NOTCH3	Q9UM47-1.2	L1111P	Neutral	0.057
NOTCH3	Q9UM47-1.2	L1111Q	Neutral	0.014
NOTCH3	Q9UM47-1.2	L1111R	Neutral	0.014
NOTCH3	Q9UM47-1.2	L1111S	Neutral	0.012
NOTCH3	Q9UM47-1.2	L1111T	Neutral	0.003
NOTCH3	Q9UM47-1.2	L1111V	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1111W	Neutral	0.013
NOTCH3	Q9UM47-1.2	L1111Y	Neutral	0.003
NOTCH3	Q9UM47-1.2	P1112A	Neutral	0.178
NOTCH3	Q9UM47-1.2	P1112C	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	P1112D	Neutral	0.192
NOTCH3	Q9UM47-1.2	P1112E	Neutral	0.181
NOTCH3	Q9UM47-1.2	P1112F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	P1112G	Neutral	0.479
NOTCH3	Q9UM47-1.2	P1112H	Neutral	0.492
NOTCH3	Q9UM47-1.2	P1112I	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	P1112K	Neutral	0.167
NOTCH3	Q9UM47-1.2	P1112L	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	P1112M	Neutral	0.486
NOTCH3	Q9UM47-1.2	P1112N	Pathogenic	0.514
NOTCH3	Q9UM47-1.2	P1112Q	Neutral	0.178
NOTCH3	Q9UM47-1.2	P1112R	Neutral	0.465
NOTCH3	Q9UM47-1.2	P1112S	Neutral	0.182
NOTCH3	Q9UM47-1.2	P1112T	Neutral	0.189
NOTCH3	Q9UM47-1.2	P1112V	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	P1112W	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	P1112Y	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	G1113A	Neutral	0.23
NOTCH3	Q9UM47-1.2	G1113C	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G1113D	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	G1113E	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	G1113F	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G1113H	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G1113I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1113K	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	G1113L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1113M	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G1113N	Neutral	0.211
NOTCH3	Q9UM47-1.2	G1113P	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	G1113Q	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G1113R	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	G1113S	Neutral	0.225
NOTCH3	Q9UM47-1.2	G1113T	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G1113V	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G1113W	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	G1113Y	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	Y1114A	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	Y1114C	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	Y1114D	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	Y1114E	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	Y1114F	Neutral	0.019
NOTCH3	Q9UM47-1.2	Y1114G	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	Y1114H	Neutral	0.076
NOTCH3	Q9UM47-1.2	Y1114I	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	Y1114K	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	Y1114L	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	Y1114M	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	Y1114N	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	Y1114P	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	Y1114Q	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	Y1114R	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	Y1114S	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	Y1114T	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	Y1114V	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	Y1114W	Neutral	0.076
NOTCH3	Q9UM47-1.2	N1115A	Neutral	0.006
NOTCH3	Q9UM47-1.2	N1115C	Neutral	0.031
NOTCH3	Q9UM47-1.2	N1115D	Neutral	0.0
NOTCH3	Q9UM47-1.2	N1115E	Neutral	0.0
NOTCH3	Q9UM47-1.2	N1115F	Neutral	0.028
NOTCH3	Q9UM47-1.2	N1115G	Neutral	0.0
NOTCH3	Q9UM47-1.2	N1115H	Neutral	0.0
NOTCH3	Q9UM47-1.2	N1115I	Neutral	0.029
NOTCH3	Q9UM47-1.2	N1115K	Neutral	0.0
NOTCH3	Q9UM47-1.2	N1115L	Neutral	0.029
NOTCH3	Q9UM47-1.2	N1115M	Neutral	0.007
NOTCH3	Q9UM47-1.2	N1115P	Neutral	0.007
NOTCH3	Q9UM47-1.2	N1115Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	N1115R	Neutral	0.0
NOTCH3	Q9UM47-1.2	N1115S	Neutral	0.0
NOTCH3	Q9UM47-1.2	N1115T	Neutral	0.0
NOTCH3	Q9UM47-1.2	N1115V	Neutral	0.031
NOTCH3	Q9UM47-1.2	N1115W	Neutral	0.105
NOTCH3	Q9UM47-1.2	N1115Y	Neutral	0.006
NOTCH3	Q9UM47-1.2	G1116A	Neutral	0.22
NOTCH3	Q9UM47-1.2	G1116C	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G1116D	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	G1116E	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	G1116F	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G1116H	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	G1116I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1116K	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	G1116L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1116M	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G1116N	Neutral	0.202
NOTCH3	Q9UM47-1.2	G1116P	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	G1116Q	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	G1116R	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	G1116S	Neutral	0.216
NOTCH3	Q9UM47-1.2	G1116T	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	G1116V	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1116W	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	G1116Y	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	D1117A	Neutral	0.068
NOTCH3	Q9UM47-1.2	D1117C	Neutral	0.264
NOTCH3	Q9UM47-1.2	D1117E	Neutral	0.0
NOTCH3	Q9UM47-1.2	D1117F	Neutral	0.237
NOTCH3	Q9UM47-1.2	D1117G	Neutral	0.015
NOTCH3	Q9UM47-1.2	D1117H	Neutral	0.016
NOTCH3	Q9UM47-1.2	D1117I	Neutral	0.245
NOTCH3	Q9UM47-1.2	D1117K	Neutral	0.014
NOTCH3	Q9UM47-1.2	D1117L	Pathogenic	0.596
NOTCH3	Q9UM47-1.2	D1117M	Neutral	0.244
NOTCH3	Q9UM47-1.2	D1117N	Neutral	0.001
NOTCH3	Q9UM47-1.2	D1117P	Neutral	0.017
NOTCH3	Q9UM47-1.2	D1117Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	D1117R	Neutral	0.06
NOTCH3	Q9UM47-1.2	D1117S	Neutral	0.004
NOTCH3	Q9UM47-1.2	D1117T	Neutral	0.017
NOTCH3	Q9UM47-1.2	D1117V	Neutral	0.257
NOTCH3	Q9UM47-1.2	D1117W	Pathogenic	0.56
NOTCH3	Q9UM47-1.2	D1117Y	Neutral	0.231
NOTCH3	Q9UM47-1.2	N1118A	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	N1118C	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	N1118D	Neutral	0.102
NOTCH3	Q9UM47-1.2	N1118E	Neutral	0.333
NOTCH3	Q9UM47-1.2	N1118F	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	N1118G	Neutral	0.305
NOTCH3	Q9UM47-1.2	N1118H	Neutral	0.096
NOTCH3	Q9UM47-1.2	N1118I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	N1118K	Neutral	0.312
NOTCH3	Q9UM47-1.2	N1118L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	N1118M	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	N1118P	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	N1118Q	Neutral	0.329
NOTCH3	Q9UM47-1.2	N1118R	Neutral	0.301
NOTCH3	Q9UM47-1.2	N1118S	Neutral	0.096
NOTCH3	Q9UM47-1.2	N1118T	Neutral	0.343
NOTCH3	Q9UM47-1.2	N1118V	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	N1118W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	N1118Y	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	C1119A	Neutral	0.49
NOTCH3	Q9UM47-1.2	C1119D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1119E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1119F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C1119G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1119H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1119I	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C1119K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1119L	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C1119M	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C1119N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1119P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1119Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1119R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1119S	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C1119T	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	C1119V	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C1119W	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	C1119Y	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	E1120A	Neutral	0.412
NOTCH3	Q9UM47-1.2	E1120C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	E1120D	Neutral	0.008
NOTCH3	Q9UM47-1.2	E1120F	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	E1120G	Pathogenic	0.747
NOTCH3	Q9UM47-1.2	E1120H	Neutral	0.149
NOTCH3	Q9UM47-1.2	E1120I	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	E1120K	Neutral	0.035
NOTCH3	Q9UM47-1.2	E1120L	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	E1120M	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	E1120N	Neutral	0.146
NOTCH3	Q9UM47-1.2	E1120P	Neutral	0.435
NOTCH3	Q9UM47-1.2	E1120Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	E1120R	Neutral	0.134
NOTCH3	Q9UM47-1.2	E1120S	Neutral	0.136
NOTCH3	Q9UM47-1.2	E1120T	Neutral	0.437
NOTCH3	Q9UM47-1.2	E1120V	Pathogenic	0.788
NOTCH3	Q9UM47-1.2	E1120W	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	E1120Y	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	D1121A	Neutral	0.077
NOTCH3	Q9UM47-1.2	D1121C	Neutral	0.292
NOTCH3	Q9UM47-1.2	D1121E	Neutral	0.0
NOTCH3	Q9UM47-1.2	D1121F	Neutral	0.263
NOTCH3	Q9UM47-1.2	D1121G	Neutral	0.017
NOTCH3	Q9UM47-1.2	D1121H	Neutral	0.018
NOTCH3	Q9UM47-1.2	D1121I	Neutral	0.271
NOTCH3	Q9UM47-1.2	D1121K	Neutral	0.017
NOTCH3	Q9UM47-1.2	D1121L	Pathogenic	0.629
NOTCH3	Q9UM47-1.2	D1121M	Neutral	0.271
NOTCH3	Q9UM47-1.2	D1121N	Neutral	0.001
NOTCH3	Q9UM47-1.2	D1121P	Neutral	0.02
NOTCH3	Q9UM47-1.2	D1121Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	D1121R	Neutral	0.068
NOTCH3	Q9UM47-1.2	D1121S	Neutral	0.004
NOTCH3	Q9UM47-1.2	D1121T	Neutral	0.02
NOTCH3	Q9UM47-1.2	D1121V	Neutral	0.285
NOTCH3	Q9UM47-1.2	D1121W	Pathogenic	0.594
NOTCH3	Q9UM47-1.2	D1121Y	Neutral	0.257
NOTCH3	Q9UM47-1.2	D1122A	Neutral	0.232
NOTCH3	Q9UM47-1.2	D1122C	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	D1122E	Neutral	0.001
NOTCH3	Q9UM47-1.2	D1122F	Pathogenic	0.562
NOTCH3	Q9UM47-1.2	D1122G	Neutral	0.058
NOTCH3	Q9UM47-1.2	D1122H	Neutral	0.061
NOTCH3	Q9UM47-1.2	D1122I	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	D1122K	Neutral	0.057
NOTCH3	Q9UM47-1.2	D1122L	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	D1122M	Pathogenic	0.572
NOTCH3	Q9UM47-1.2	D1122N	Neutral	0.003
NOTCH3	Q9UM47-1.2	D1122P	Neutral	0.068
NOTCH3	Q9UM47-1.2	D1122Q	Neutral	0.014
NOTCH3	Q9UM47-1.2	D1122R	Neutral	0.209
NOTCH3	Q9UM47-1.2	D1122S	Neutral	0.015
NOTCH3	Q9UM47-1.2	D1122T	Neutral	0.067
NOTCH3	Q9UM47-1.2	D1122V	Pathogenic	0.59
NOTCH3	Q9UM47-1.2	D1122W	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	D1122Y	Pathogenic	0.555
NOTCH3	Q9UM47-1.2	V1123A	Neutral	0.132
NOTCH3	Q9UM47-1.2	V1123C	Neutral	0.425
NOTCH3	Q9UM47-1.2	V1123D	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	V1123E	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	V1123F	Neutral	0.416
NOTCH3	Q9UM47-1.2	V1123G	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	V1123H	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	V1123I	Neutral	0.002
NOTCH3	Q9UM47-1.2	V1123K	Pathogenic	0.767
NOTCH3	Q9UM47-1.2	V1123L	Neutral	0.035
NOTCH3	Q9UM47-1.2	V1123M	Neutral	0.034
NOTCH3	Q9UM47-1.2	V1123N	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	V1123P	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	V1123Q	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	V1123R	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	V1123S	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	V1123T	Neutral	0.144
NOTCH3	Q9UM47-1.2	V1123W	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	V1123Y	Neutral	0.409
NOTCH3	Q9UM47-1.2	D1124A	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	D1124C	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	D1124E	Neutral	0.006
NOTCH3	Q9UM47-1.2	D1124F	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	D1124G	Neutral	0.334
NOTCH3	Q9UM47-1.2	D1124H	Neutral	0.348
NOTCH3	Q9UM47-1.2	D1124I	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	D1124K	Neutral	0.332
NOTCH3	Q9UM47-1.2	D1124L	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	D1124M	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	D1124N	Neutral	0.027
NOTCH3	Q9UM47-1.2	D1124P	Neutral	0.372
NOTCH3	Q9UM47-1.2	D1124Q	Neutral	0.106
NOTCH3	Q9UM47-1.2	D1124R	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	D1124S	Neutral	0.108
NOTCH3	Q9UM47-1.2	D1124T	Neutral	0.37
NOTCH3	Q9UM47-1.2	D1124V	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	D1124W	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	D1124Y	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	E1125A	Pathogenic	0.72
NOTCH3	Q9UM47-1.2	E1125C	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	E1125D	Neutral	0.029
NOTCH3	Q9UM47-1.2	E1125F	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	E1125G	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	E1125H	Neutral	0.391
NOTCH3	Q9UM47-1.2	E1125I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	E1125K	Neutral	0.116
NOTCH3	Q9UM47-1.2	E1125L	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	E1125M	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	E1125N	Neutral	0.386
NOTCH3	Q9UM47-1.2	E1125P	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	E1125Q	Neutral	0.03
NOTCH3	Q9UM47-1.2	E1125R	Neutral	0.363
NOTCH3	Q9UM47-1.2	E1125S	Neutral	0.366
NOTCH3	Q9UM47-1.2	E1125T	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	E1125V	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	E1125W	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	E1125Y	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	C1126A	Neutral	0.498
NOTCH3	Q9UM47-1.2	C1126D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1126E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1126F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	C1126G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1126H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1126I	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1126K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1126L	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C1126M	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C1126N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1126P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1126Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1126R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1126S	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C1126T	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C1126V	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C1126W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C1126Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	A1127C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1127D	Neutral	0.057
NOTCH3	Q9UM47-1.2	A1127E	Neutral	0.012
NOTCH3	Q9UM47-1.2	A1127F	Neutral	0.049
NOTCH3	Q9UM47-1.2	A1127G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1127H	Neutral	0.052
NOTCH3	Q9UM47-1.2	A1127I	Neutral	0.012
NOTCH3	Q9UM47-1.2	A1127K	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1127L	Neutral	0.012
NOTCH3	Q9UM47-1.2	A1127M	Neutral	0.012
NOTCH3	Q9UM47-1.2	A1127N	Neutral	0.056
NOTCH3	Q9UM47-1.2	A1127P	Neutral	0.013
NOTCH3	Q9UM47-1.2	A1127Q	Neutral	0.012
NOTCH3	Q9UM47-1.2	A1127R	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1127S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1127T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1127V	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1127W	Neutral	0.174
NOTCH3	Q9UM47-1.2	A1127Y	Neutral	0.048
NOTCH3	Q9UM47-1.2	S1128A	Neutral	0.019
NOTCH3	Q9UM47-1.2	S1128C	Neutral	0.284
NOTCH3	Q9UM47-1.2	S1128D	Neutral	0.078
NOTCH3	Q9UM47-1.2	S1128E	Neutral	0.074
NOTCH3	Q9UM47-1.2	S1128F	Pathogenic	0.6
NOTCH3	Q9UM47-1.2	S1128G	Neutral	0.076
NOTCH3	Q9UM47-1.2	S1128H	Neutral	0.258
NOTCH3	Q9UM47-1.2	S1128I	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	S1128K	Neutral	0.067
NOTCH3	Q9UM47-1.2	S1128L	Pathogenic	0.61
NOTCH3	Q9UM47-1.2	S1128M	Neutral	0.255
NOTCH3	Q9UM47-1.2	S1128N	Neutral	0.018
NOTCH3	Q9UM47-1.2	S1128P	Neutral	0.28
NOTCH3	Q9UM47-1.2	S1128Q	Neutral	0.072
NOTCH3	Q9UM47-1.2	S1128R	Neutral	0.238
NOTCH3	Q9UM47-1.2	S1128T	Neutral	0.018
NOTCH3	Q9UM47-1.2	S1128V	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	S1128W	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	S1128Y	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	Q1129A	Neutral	0.355
NOTCH3	Q9UM47-1.2	Q1129C	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	Q1129D	Neutral	0.117
NOTCH3	Q9UM47-1.2	Q1129E	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q1129F	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	Q1129G	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	Q1129H	Neutral	0.125
NOTCH3	Q9UM47-1.2	Q1129I	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	Q1129K	Neutral	0.029
NOTCH3	Q9UM47-1.2	Q1129L	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	Q1129M	Neutral	0.123
NOTCH3	Q9UM47-1.2	Q1129N	Neutral	0.119
NOTCH3	Q9UM47-1.2	Q1129P	Neutral	0.377
NOTCH3	Q9UM47-1.2	Q1129R	Neutral	0.027
NOTCH3	Q9UM47-1.2	Q1129S	Neutral	0.11
NOTCH3	Q9UM47-1.2	Q1129T	Neutral	0.378
NOTCH3	Q9UM47-1.2	Q1129V	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	Q1129W	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	Q1129Y	Neutral	0.374
NOTCH3	Q9UM47-1.2	P1130A	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	P1130C	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	P1130D	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	P1130E	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	P1130F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P1130G	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	P1130H	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	P1130I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P1130K	Pathogenic	0.672
NOTCH3	Q9UM47-1.2	P1130L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P1130M	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	P1130N	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	P1130Q	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	P1130R	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	P1130S	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	P1130T	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	P1130V	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	P1130W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P1130Y	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	C1131A	Neutral	0.5
NOTCH3	Q9UM47-1.2	C1131D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1131E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1131F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	C1131G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1131H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1131I	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C1131K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1131L	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C1131M	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1131N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1131P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1131Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1131R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1131S	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C1131T	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C1131V	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1131W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C1131Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	Q1132A	Pathogenic	0.636
NOTCH3	Q9UM47-1.2	Q1132C	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	Q1132D	Neutral	0.296
NOTCH3	Q9UM47-1.2	Q1132E	Neutral	0.021
NOTCH3	Q9UM47-1.2	Q1132F	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	Q1132G	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	Q1132H	Neutral	0.312
NOTCH3	Q9UM47-1.2	Q1132I	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	Q1132K	Neutral	0.085
NOTCH3	Q9UM47-1.2	Q1132L	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	Q1132M	Neutral	0.309
NOTCH3	Q9UM47-1.2	Q1132N	Neutral	0.3
NOTCH3	Q9UM47-1.2	Q1132P	Pathogenic	0.657
NOTCH3	Q9UM47-1.2	Q1132R	Neutral	0.082
NOTCH3	Q9UM47-1.2	Q1132S	Neutral	0.282
NOTCH3	Q9UM47-1.2	Q1132T	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	Q1132V	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	Q1132W	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	Q1132Y	Pathogenic	0.655
NOTCH3	Q9UM47-1.2	H1133A	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	H1133C	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	H1133D	Neutral	0.246
NOTCH3	Q9UM47-1.2	H1133E	Neutral	0.071
NOTCH3	Q9UM47-1.2	H1133F	Neutral	0.254
NOTCH3	Q9UM47-1.2	H1133G	Pathogenic	0.555
NOTCH3	Q9UM47-1.2	H1133I	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	H1133K	Neutral	0.253
NOTCH3	Q9UM47-1.2	H1133L	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	H1133M	Pathogenic	0.617
NOTCH3	Q9UM47-1.2	H1133N	Neutral	0.016
NOTCH3	Q9UM47-1.2	H1133P	Pathogenic	0.596
NOTCH3	Q9UM47-1.2	H1133Q	Neutral	0.072
NOTCH3	Q9UM47-1.2	H1133R	Neutral	0.066
NOTCH3	Q9UM47-1.2	H1133S	Neutral	0.232
NOTCH3	Q9UM47-1.2	H1133T	Pathogenic	0.598
NOTCH3	Q9UM47-1.2	H1133V	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	H1133W	Pathogenic	0.583
NOTCH3	Q9UM47-1.2	H1133Y	Neutral	0.003
NOTCH3	Q9UM47-1.2	G1134A	Neutral	0.234
NOTCH3	Q9UM47-1.2	G1134C	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G1134D	Pathogenic	0.56
NOTCH3	Q9UM47-1.2	G1134E	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	G1134F	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G1134H	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	G1134I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1134K	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	G1134L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1134M	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1134N	Neutral	0.215
NOTCH3	Q9UM47-1.2	G1134P	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	G1134Q	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	G1134R	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G1134S	Neutral	0.23
NOTCH3	Q9UM47-1.2	G1134T	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	G1134V	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	G1134W	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	G1134Y	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G1135A	Neutral	0.241
NOTCH3	Q9UM47-1.2	G1135C	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	G1135D	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	G1135E	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	G1135F	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1135H	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	G1135I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1135K	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	G1135L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1135M	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G1135N	Neutral	0.222
NOTCH3	Q9UM47-1.2	G1135P	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	G1135Q	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G1135R	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G1135S	Neutral	0.237
NOTCH3	Q9UM47-1.2	G1135T	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	G1135V	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G1135W	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	G1135Y	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	S1136A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1136C	Neutral	0.019
NOTCH3	Q9UM47-1.2	S1136D	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1136E	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1136F	Neutral	0.069
NOTCH3	Q9UM47-1.2	S1136G	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1136H	Neutral	0.017
NOTCH3	Q9UM47-1.2	S1136I	Neutral	0.071
NOTCH3	Q9UM47-1.2	S1136K	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1136L	Neutral	0.071
NOTCH3	Q9UM47-1.2	S1136M	Neutral	0.017
NOTCH3	Q9UM47-1.2	S1136N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1136P	Neutral	0.019
NOTCH3	Q9UM47-1.2	S1136Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1136R	Neutral	0.015
NOTCH3	Q9UM47-1.2	S1136T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1136V	Neutral	0.076
NOTCH3	Q9UM47-1.2	S1136W	Neutral	0.232
NOTCH3	Q9UM47-1.2	S1136Y	Neutral	0.067
NOTCH3	Q9UM47-1.2	C1137A	Neutral	0.499
NOTCH3	Q9UM47-1.2	C1137D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1137E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1137F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	C1137G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1137H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1137I	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1137K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1137L	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1137M	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1137N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1137P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1137Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1137R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1137S	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C1137T	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C1137V	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1137W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C1137Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	I1138A	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	I1138C	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	I1138D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	I1138E	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	I1138F	Neutral	0.489
NOTCH3	Q9UM47-1.2	I1138G	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	I1138H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	I1138K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	I1138L	Neutral	0.046
NOTCH3	Q9UM47-1.2	I1138M	Neutral	0.18
NOTCH3	Q9UM47-1.2	I1138N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	I1138P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	I1138Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	I1138R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	I1138S	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	I1138T	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	I1138V	Neutral	0.01
NOTCH3	Q9UM47-1.2	I1138W	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	I1138Y	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	D1139A	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	D1139C	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	D1139E	Neutral	0.022
NOTCH3	Q9UM47-1.2	D1139F	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	D1139G	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	D1139H	Pathogenic	0.673
NOTCH3	Q9UM47-1.2	D1139I	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	D1139K	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	D1139L	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D1139M	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	D1139N	Neutral	0.097
NOTCH3	Q9UM47-1.2	D1139P	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	D1139Q	Neutral	0.314
NOTCH3	Q9UM47-1.2	D1139R	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	D1139S	Neutral	0.319
NOTCH3	Q9UM47-1.2	D1139T	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	D1139V	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	D1139W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	D1139Y	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	L1140A	Pathogenic	0.675
NOTCH3	Q9UM47-1.2	L1140C	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	L1140D	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1140E	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L1140F	Neutral	0.35
NOTCH3	Q9UM47-1.2	L1140G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1140H	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L1140I	Neutral	0.026
NOTCH3	Q9UM47-1.2	L1140K	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	L1140M	Neutral	0.026
NOTCH3	Q9UM47-1.2	L1140N	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	L1140P	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	L1140Q	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	L1140R	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	L1140S	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	L1140T	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	L1140V	Neutral	0.103
NOTCH3	Q9UM47-1.2	L1140W	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	L1140Y	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	V1141A	Neutral	0.096
NOTCH3	Q9UM47-1.2	V1141C	Neutral	0.34
NOTCH3	Q9UM47-1.2	V1141D	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	V1141E	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	V1141F	Neutral	0.331
NOTCH3	Q9UM47-1.2	V1141G	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	V1141H	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	V1141I	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1141K	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	V1141L	Neutral	0.024
NOTCH3	Q9UM47-1.2	V1141M	Neutral	0.024
NOTCH3	Q9UM47-1.2	V1141N	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	V1141P	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	V1141Q	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	V1141R	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	V1141S	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	V1141T	Neutral	0.105
NOTCH3	Q9UM47-1.2	V1141W	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	V1141Y	Neutral	0.326
NOTCH3	Q9UM47-1.2	A1142C	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1142D	Neutral	0.132
NOTCH3	Q9UM47-1.2	A1142E	Neutral	0.03
NOTCH3	Q9UM47-1.2	A1142F	Neutral	0.114
NOTCH3	Q9UM47-1.2	A1142G	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1142H	Neutral	0.12
NOTCH3	Q9UM47-1.2	A1142I	Neutral	0.029
NOTCH3	Q9UM47-1.2	A1142K	Neutral	0.027
NOTCH3	Q9UM47-1.2	A1142L	Neutral	0.029
NOTCH3	Q9UM47-1.2	A1142M	Neutral	0.029
NOTCH3	Q9UM47-1.2	A1142N	Neutral	0.13
NOTCH3	Q9UM47-1.2	A1142P	Neutral	0.032
NOTCH3	Q9UM47-1.2	A1142Q	Neutral	0.03
NOTCH3	Q9UM47-1.2	A1142R	Neutral	0.026
NOTCH3	Q9UM47-1.2	A1142S	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1142T	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1142V	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1142W	Neutral	0.345
NOTCH3	Q9UM47-1.2	A1142Y	Neutral	0.111
NOTCH3	Q9UM47-1.2	R1143A	Neutral	0.048
NOTCH3	Q9UM47-1.2	R1143C	Pathogenic	0.531
NOTCH3	Q9UM47-1.2	R1143D	Neutral	0.2
NOTCH3	Q9UM47-1.2	R1143E	Neutral	0.013
NOTCH3	Q9UM47-1.2	R1143F	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	R1143G	Neutral	0.176
NOTCH3	Q9UM47-1.2	R1143H	Neutral	0.013
NOTCH3	Q9UM47-1.2	R1143I	Pathogenic	0.569
NOTCH3	Q9UM47-1.2	R1143K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1143L	Neutral	0.225
NOTCH3	Q9UM47-1.2	R1143M	Neutral	0.06
NOTCH3	Q9UM47-1.2	R1143N	Neutral	0.012
NOTCH3	Q9UM47-1.2	R1143P	Neutral	0.202
NOTCH3	Q9UM47-1.2	R1143Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R1143S	Neutral	0.049
NOTCH3	Q9UM47-1.2	R1143T	Neutral	0.053
NOTCH3	Q9UM47-1.2	R1143V	Pathogenic	0.55
NOTCH3	Q9UM47-1.2	R1143W	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	R1143Y	Neutral	0.235
NOTCH3	Q9UM47-1.2	Y1144A	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	Y1144C	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	Y1144D	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	Y1144E	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	Y1144F	Neutral	0.009
NOTCH3	Q9UM47-1.2	Y1144G	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	Y1144H	Neutral	0.035
NOTCH3	Q9UM47-1.2	Y1144I	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	Y1144K	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	Y1144L	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	Y1144M	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	Y1144N	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	Y1144P	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	Y1144Q	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	Y1144R	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	Y1144S	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	Y1144T	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	Y1144V	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	Y1144W	Neutral	0.036
NOTCH3	Q9UM47-1.2	L1145A	Neutral	0.018
NOTCH3	Q9UM47-1.2	L1145C	Neutral	0.019
NOTCH3	Q9UM47-1.2	L1145D	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	L1145E	Neutral	0.307
NOTCH3	Q9UM47-1.2	L1145F	Neutral	0.005
NOTCH3	Q9UM47-1.2	L1145G	Pathogenic	0.613
NOTCH3	Q9UM47-1.2	L1145H	Neutral	0.313
NOTCH3	Q9UM47-1.2	L1145I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1145K	Neutral	0.09
NOTCH3	Q9UM47-1.2	L1145M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1145N	Neutral	0.296
NOTCH3	Q9UM47-1.2	L1145P	Neutral	0.289
NOTCH3	Q9UM47-1.2	L1145Q	Neutral	0.09
NOTCH3	Q9UM47-1.2	L1145R	Neutral	0.086
NOTCH3	Q9UM47-1.2	L1145S	Neutral	0.078
NOTCH3	Q9UM47-1.2	L1145T	Neutral	0.02
NOTCH3	Q9UM47-1.2	L1145V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1145W	Neutral	0.08
NOTCH3	Q9UM47-1.2	L1145Y	Neutral	0.02
NOTCH3	Q9UM47-1.2	C1146A	Neutral	0.499
NOTCH3	Q9UM47-1.2	C1146D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1146E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1146F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	C1146G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1146H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1146I	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1146K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1146L	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1146M	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1146N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1146P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1146Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1146R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1146S	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C1146T	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C1146V	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1146W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C1146Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	S1147A	Neutral	0.072
NOTCH3	Q9UM47-1.2	S1147C	Pathogenic	0.61
NOTCH3	Q9UM47-1.2	S1147D	Neutral	0.252
NOTCH3	Q9UM47-1.2	S1147E	Neutral	0.239
NOTCH3	Q9UM47-1.2	S1147F	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	S1147G	Neutral	0.246
NOTCH3	Q9UM47-1.2	S1147H	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	S1147I	Pathogenic	0.861
NOTCH3	Q9UM47-1.2	S1147K	Neutral	0.221
NOTCH3	Q9UM47-1.2	S1147L	Pathogenic	0.861
NOTCH3	Q9UM47-1.2	S1147M	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	S1147N	Neutral	0.067
NOTCH3	Q9UM47-1.2	S1147P	Pathogenic	0.606
NOTCH3	Q9UM47-1.2	S1147Q	Neutral	0.235
NOTCH3	Q9UM47-1.2	S1147R	Pathogenic	0.552
NOTCH3	Q9UM47-1.2	S1147T	Neutral	0.068
NOTCH3	Q9UM47-1.2	S1147V	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	S1147W	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	S1147Y	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	C1148A	Neutral	0.499
NOTCH3	Q9UM47-1.2	C1148D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1148E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1148F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	C1148G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1148H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1148I	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1148K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1148L	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1148M	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1148N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1148P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1148Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1148R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1148S	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C1148T	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C1148V	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1148W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C1148Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	P1149A	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	P1149C	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	P1149D	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	P1149E	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	P1149F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P1149G	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	P1149H	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	P1149I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P1149K	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	P1149L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P1149M	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	P1149N	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	P1149Q	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	P1149R	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	P1149S	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	P1149T	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	P1149V	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	P1149W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P1149Y	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	P1150A	Neutral	0.235
NOTCH3	Q9UM47-1.2	P1150C	Pathogenic	0.873
NOTCH3	Q9UM47-1.2	P1150D	Neutral	0.253
NOTCH3	Q9UM47-1.2	P1150E	Neutral	0.24
NOTCH3	Q9UM47-1.2	P1150F	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	P1150G	Pathogenic	0.566
NOTCH3	Q9UM47-1.2	P1150H	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	P1150I	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	P1150K	Neutral	0.222
NOTCH3	Q9UM47-1.2	P1150L	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	P1150M	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	P1150N	Pathogenic	0.601
NOTCH3	Q9UM47-1.2	P1150Q	Neutral	0.235
NOTCH3	Q9UM47-1.2	P1150R	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	P1150S	Neutral	0.24
NOTCH3	Q9UM47-1.2	P1150T	Neutral	0.25
NOTCH3	Q9UM47-1.2	P1150V	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	P1150W	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	P1150Y	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	G1151A	Neutral	0.234
NOTCH3	Q9UM47-1.2	G1151C	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G1151D	Pathogenic	0.56
NOTCH3	Q9UM47-1.2	G1151E	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	G1151F	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G1151H	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	G1151I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1151K	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	G1151L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1151M	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1151N	Neutral	0.215
NOTCH3	Q9UM47-1.2	G1151P	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	G1151Q	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	G1151R	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	G1151S	Neutral	0.229
NOTCH3	Q9UM47-1.2	G1151T	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	G1151V	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	G1151W	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	G1151Y	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	T1152A	Neutral	0.456
NOTCH3	Q9UM47-1.2	T1152C	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	T1152D	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	T1152E	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	T1152F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	T1152G	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	T1152H	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	T1152I	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	T1152K	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	T1152L	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	T1152M	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	T1152N	Neutral	0.48
NOTCH3	Q9UM47-1.2	T1152P	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	T1152Q	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	T1152R	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	T1152S	Neutral	0.159
NOTCH3	Q9UM47-1.2	T1152V	Neutral	0.472
NOTCH3	Q9UM47-1.2	T1152W	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	T1152Y	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	L1153A	Neutral	0.042
NOTCH3	Q9UM47-1.2	L1153C	Neutral	0.045
NOTCH3	Q9UM47-1.2	L1153D	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	L1153E	Pathogenic	0.521
NOTCH3	Q9UM47-1.2	L1153F	Neutral	0.011
NOTCH3	Q9UM47-1.2	L1153G	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	L1153H	Pathogenic	0.528
NOTCH3	Q9UM47-1.2	L1153I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1153K	Neutral	0.195
NOTCH3	Q9UM47-1.2	L1153M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1153N	Pathogenic	0.508
NOTCH3	Q9UM47-1.2	L1153P	Neutral	0.499
NOTCH3	Q9UM47-1.2	L1153Q	Neutral	0.195
NOTCH3	Q9UM47-1.2	L1153R	Neutral	0.188
NOTCH3	Q9UM47-1.2	L1153S	Neutral	0.171
NOTCH3	Q9UM47-1.2	L1153T	Neutral	0.047
NOTCH3	Q9UM47-1.2	L1153V	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1153W	Neutral	0.176
NOTCH3	Q9UM47-1.2	L1153Y	Neutral	0.049
NOTCH3	Q9UM47-1.2	G1154A	Neutral	0.227
NOTCH3	Q9UM47-1.2	G1154C	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G1154D	Pathogenic	0.55
NOTCH3	Q9UM47-1.2	G1154E	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	G1154F	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G1154H	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	G1154I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1154K	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G1154L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1154M	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G1154N	Neutral	0.208
NOTCH3	Q9UM47-1.2	G1154P	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G1154Q	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G1154R	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	G1154S	Neutral	0.222
NOTCH3	Q9UM47-1.2	G1154T	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G1154V	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G1154W	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	G1154Y	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	V1155A	Neutral	0.103
NOTCH3	Q9UM47-1.2	V1155C	Neutral	0.358
NOTCH3	Q9UM47-1.2	V1155D	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	V1155E	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	V1155F	Neutral	0.349
NOTCH3	Q9UM47-1.2	V1155G	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	V1155H	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	V1155I	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1155K	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	V1155L	Neutral	0.026
NOTCH3	Q9UM47-1.2	V1155M	Neutral	0.026
NOTCH3	Q9UM47-1.2	V1155N	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	V1155P	Pathogenic	0.721
NOTCH3	Q9UM47-1.2	V1155Q	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	V1155R	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	V1155S	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	V1155T	Neutral	0.112
NOTCH3	Q9UM47-1.2	V1155W	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	V1155Y	Neutral	0.343
NOTCH3	Q9UM47-1.2	L1156A	Neutral	0.126
NOTCH3	Q9UM47-1.2	L1156C	Neutral	0.134
NOTCH3	Q9UM47-1.2	L1156D	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	L1156E	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	L1156F	Neutral	0.036
NOTCH3	Q9UM47-1.2	L1156G	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	L1156H	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	L1156I	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1156K	Neutral	0.442
NOTCH3	Q9UM47-1.2	L1156M	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1156N	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	L1156P	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	L1156Q	Neutral	0.441
NOTCH3	Q9UM47-1.2	L1156R	Neutral	0.43
NOTCH3	Q9UM47-1.2	L1156S	Neutral	0.402
NOTCH3	Q9UM47-1.2	L1156T	Neutral	0.137
NOTCH3	Q9UM47-1.2	L1156V	Neutral	0.008
NOTCH3	Q9UM47-1.2	L1156W	Neutral	0.411
NOTCH3	Q9UM47-1.2	L1156Y	Neutral	0.143
NOTCH3	Q9UM47-1.2	C1157A	Neutral	0.477
NOTCH3	Q9UM47-1.2	C1157D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1157E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1157F	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	C1157G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1157H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1157I	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	C1157K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1157L	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	C1157M	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	C1157N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1157P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1157Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1157R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1157S	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C1157T	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C1157V	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C1157W	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	C1157Y	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	E1158A	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	E1158C	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	E1158D	Neutral	0.04
NOTCH3	Q9UM47-1.2	E1158F	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	E1158G	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	E1158H	Neutral	0.474
NOTCH3	Q9UM47-1.2	E1158I	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	E1158K	Neutral	0.156
NOTCH3	Q9UM47-1.2	E1158L	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	E1158M	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	E1158N	Neutral	0.469
NOTCH3	Q9UM47-1.2	E1158P	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	E1158Q	Neutral	0.042
NOTCH3	Q9UM47-1.2	E1158R	Neutral	0.445
NOTCH3	Q9UM47-1.2	E1158S	Neutral	0.448
NOTCH3	Q9UM47-1.2	E1158T	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	E1158V	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	E1158W	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	E1158Y	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	I1159A	Pathogenic	0.566
NOTCH3	Q9UM47-1.2	I1159C	Pathogenic	0.582
NOTCH3	Q9UM47-1.2	I1159D	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	I1159E	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	I1159F	Neutral	0.252
NOTCH3	Q9UM47-1.2	I1159G	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	I1159H	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	I1159K	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	I1159L	Neutral	0.017
NOTCH3	Q9UM47-1.2	I1159M	Neutral	0.072
NOTCH3	Q9UM47-1.2	I1159N	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	I1159P	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	I1159Q	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	I1159R	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	I1159S	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	I1159T	Pathogenic	0.59
NOTCH3	Q9UM47-1.2	I1159V	Neutral	0.003
NOTCH3	Q9UM47-1.2	I1159W	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	I1159Y	Pathogenic	0.602
NOTCH3	Q9UM47-1.2	N1160A	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	N1160C	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	N1160D	Neutral	0.121
NOTCH3	Q9UM47-1.2	N1160E	Neutral	0.378
NOTCH3	Q9UM47-1.2	N1160F	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	N1160G	Neutral	0.348
NOTCH3	Q9UM47-1.2	N1160H	Neutral	0.115
NOTCH3	Q9UM47-1.2	N1160I	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	N1160K	Neutral	0.355
NOTCH3	Q9UM47-1.2	N1160L	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	N1160M	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	N1160P	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	N1160Q	Neutral	0.374
NOTCH3	Q9UM47-1.2	N1160R	Neutral	0.344
NOTCH3	Q9UM47-1.2	N1160S	Neutral	0.114
NOTCH3	Q9UM47-1.2	N1160T	Neutral	0.389
NOTCH3	Q9UM47-1.2	N1160V	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	N1160W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	N1160Y	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	E1161A	Neutral	0.059
NOTCH3	Q9UM47-1.2	E1161C	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	E1161D	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1161F	Pathogenic	0.582
NOTCH3	Q9UM47-1.2	E1161G	Neutral	0.209
NOTCH3	Q9UM47-1.2	E1161H	Neutral	0.015
NOTCH3	Q9UM47-1.2	E1161I	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	E1161K	Neutral	0.003
NOTCH3	Q9UM47-1.2	E1161L	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	E1161M	Neutral	0.241
NOTCH3	Q9UM47-1.2	E1161N	Neutral	0.015
NOTCH3	Q9UM47-1.2	E1161P	Neutral	0.064
NOTCH3	Q9UM47-1.2	E1161Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1161R	Neutral	0.014
NOTCH3	Q9UM47-1.2	E1161S	Neutral	0.014
NOTCH3	Q9UM47-1.2	E1161T	Neutral	0.065
NOTCH3	Q9UM47-1.2	E1161V	Neutral	0.249
NOTCH3	Q9UM47-1.2	E1161W	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	E1161Y	Neutral	0.229
NOTCH3	Q9UM47-1.2	D1162A	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	D1162C	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	D1162E	Neutral	0.021
NOTCH3	Q9UM47-1.2	D1162F	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	D1162G	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	D1162H	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	D1162I	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	D1162K	Pathogenic	0.644
NOTCH3	Q9UM47-1.2	D1162L	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D1162M	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	D1162N	Neutral	0.092
NOTCH3	Q9UM47-1.2	D1162P	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	D1162Q	Neutral	0.301
NOTCH3	Q9UM47-1.2	D1162R	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	D1162S	Neutral	0.306
NOTCH3	Q9UM47-1.2	D1162T	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	D1162V	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	D1162W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	D1162Y	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	D1163A	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	D1163C	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	D1163E	Neutral	0.023
NOTCH3	Q9UM47-1.2	D1163F	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	D1163G	Pathogenic	0.67
NOTCH3	Q9UM47-1.2	D1163H	Pathogenic	0.684
NOTCH3	Q9UM47-1.2	D1163I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	D1163K	Pathogenic	0.669
NOTCH3	Q9UM47-1.2	D1163L	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D1163M	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	D1163N	Neutral	0.102
NOTCH3	Q9UM47-1.2	D1163P	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	D1163Q	Neutral	0.325
NOTCH3	Q9UM47-1.2	D1163R	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	D1163S	Neutral	0.33
NOTCH3	Q9UM47-1.2	D1163T	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	D1163V	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	D1163W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	D1163Y	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	C1164A	Neutral	0.474
NOTCH3	Q9UM47-1.2	C1164D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1164E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1164F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C1164G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1164H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1164I	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	C1164K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1164L	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	C1164M	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	C1164N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1164P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1164Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1164R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1164S	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1164T	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C1164V	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C1164W	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C1164Y	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	G1165A	Neutral	0.001
NOTCH3	Q9UM47-1.2	G1165C	Neutral	0.075
NOTCH3	Q9UM47-1.2	G1165D	Neutral	0.004
NOTCH3	Q9UM47-1.2	G1165E	Neutral	0.016
NOTCH3	Q9UM47-1.2	G1165F	Neutral	0.063
NOTCH3	Q9UM47-1.2	G1165H	Neutral	0.015
NOTCH3	Q9UM47-1.2	G1165I	Neutral	0.242
NOTCH3	Q9UM47-1.2	G1165K	Neutral	0.014
NOTCH3	Q9UM47-1.2	G1165L	Neutral	0.242
NOTCH3	Q9UM47-1.2	G1165M	Neutral	0.065
NOTCH3	Q9UM47-1.2	G1165N	Neutral	0.001
NOTCH3	Q9UM47-1.2	G1165P	Neutral	0.017
NOTCH3	Q9UM47-1.2	G1165Q	Neutral	0.016
NOTCH3	Q9UM47-1.2	G1165R	Neutral	0.014
NOTCH3	Q9UM47-1.2	G1165S	Neutral	0.001
NOTCH3	Q9UM47-1.2	G1165T	Neutral	0.017
NOTCH3	Q9UM47-1.2	G1165V	Neutral	0.07
NOTCH3	Q9UM47-1.2	G1165W	Neutral	0.013
NOTCH3	Q9UM47-1.2	G1165Y	Neutral	0.061
NOTCH3	Q9UM47-1.2	P1166A	Neutral	0.196
NOTCH3	Q9UM47-1.2	P1166C	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	P1166D	Neutral	0.212
NOTCH3	Q9UM47-1.2	P1166E	Neutral	0.2
NOTCH3	Q9UM47-1.2	P1166F	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	P1166G	Pathogenic	0.509
NOTCH3	Q9UM47-1.2	P1166H	Pathogenic	0.522
NOTCH3	Q9UM47-1.2	P1166I	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	P1166K	Neutral	0.185
NOTCH3	Q9UM47-1.2	P1166L	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	P1166M	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	P1166N	Pathogenic	0.545
NOTCH3	Q9UM47-1.2	P1166Q	Neutral	0.197
NOTCH3	Q9UM47-1.2	P1166R	Neutral	0.496
NOTCH3	Q9UM47-1.2	P1166S	Neutral	0.201
NOTCH3	Q9UM47-1.2	P1166T	Neutral	0.209
NOTCH3	Q9UM47-1.2	P1166V	Pathogenic	0.535
NOTCH3	Q9UM47-1.2	P1166W	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	P1166Y	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	G1167A	Neutral	0.003
NOTCH3	Q9UM47-1.2	G1167C	Neutral	0.198
NOTCH3	Q9UM47-1.2	G1167D	Neutral	0.012
NOTCH3	Q9UM47-1.2	G1167E	Neutral	0.047
NOTCH3	Q9UM47-1.2	G1167F	Neutral	0.171
NOTCH3	Q9UM47-1.2	G1167H	Neutral	0.046
NOTCH3	Q9UM47-1.2	G1167I	Neutral	0.495
NOTCH3	Q9UM47-1.2	G1167K	Neutral	0.043
NOTCH3	Q9UM47-1.2	G1167L	Neutral	0.495
NOTCH3	Q9UM47-1.2	G1167M	Neutral	0.176
NOTCH3	Q9UM47-1.2	G1167N	Neutral	0.003
NOTCH3	Q9UM47-1.2	G1167P	Neutral	0.051
NOTCH3	Q9UM47-1.2	G1167Q	Neutral	0.046
NOTCH3	Q9UM47-1.2	G1167R	Neutral	0.041
NOTCH3	Q9UM47-1.2	G1167S	Neutral	0.003
NOTCH3	Q9UM47-1.2	G1167T	Neutral	0.05
NOTCH3	Q9UM47-1.2	G1167V	Neutral	0.187
NOTCH3	Q9UM47-1.2	G1167W	Neutral	0.039
NOTCH3	Q9UM47-1.2	G1167Y	Neutral	0.167
NOTCH3	Q9UM47-1.2	P1168A	Neutral	0.013
NOTCH3	Q9UM47-1.2	P1168C	Neutral	0.223
NOTCH3	Q9UM47-1.2	P1168D	Neutral	0.014
NOTCH3	Q9UM47-1.2	P1168E	Neutral	0.013
NOTCH3	Q9UM47-1.2	P1168F	Pathogenic	0.529
NOTCH3	Q9UM47-1.2	P1168G	Neutral	0.052
NOTCH3	Q9UM47-1.2	P1168H	Neutral	0.054
NOTCH3	Q9UM47-1.2	P1168I	Neutral	0.205
NOTCH3	Q9UM47-1.2	P1168K	Neutral	0.012
NOTCH3	Q9UM47-1.2	P1168L	Neutral	0.204
NOTCH3	Q9UM47-1.2	P1168M	Neutral	0.053
NOTCH3	Q9UM47-1.2	P1168N	Neutral	0.059
NOTCH3	Q9UM47-1.2	P1168Q	Neutral	0.013
NOTCH3	Q9UM47-1.2	P1168R	Neutral	0.049
NOTCH3	Q9UM47-1.2	P1168S	Neutral	0.013
NOTCH3	Q9UM47-1.2	P1168T	Neutral	0.014
NOTCH3	Q9UM47-1.2	P1168V	Neutral	0.057
NOTCH3	Q9UM47-1.2	P1168W	Pathogenic	0.503
NOTCH3	Q9UM47-1.2	P1168Y	Neutral	0.193
NOTCH3	Q9UM47-1.2	P1169A	Neutral	0.15
NOTCH3	Q9UM47-1.2	P1169C	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	P1169D	Neutral	0.162
NOTCH3	Q9UM47-1.2	P1169E	Neutral	0.153
NOTCH3	Q9UM47-1.2	P1169F	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	P1169G	Neutral	0.428
NOTCH3	Q9UM47-1.2	P1169H	Neutral	0.441
NOTCH3	Q9UM47-1.2	P1169I	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	P1169K	Neutral	0.141
NOTCH3	Q9UM47-1.2	P1169L	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	P1169M	Neutral	0.435
NOTCH3	Q9UM47-1.2	P1169N	Neutral	0.463
NOTCH3	Q9UM47-1.2	P1169Q	Neutral	0.15
NOTCH3	Q9UM47-1.2	P1169R	Neutral	0.415
NOTCH3	Q9UM47-1.2	P1169S	Neutral	0.153
NOTCH3	Q9UM47-1.2	P1169T	Neutral	0.16
NOTCH3	Q9UM47-1.2	P1169V	Neutral	0.453
NOTCH3	Q9UM47-1.2	P1169W	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	P1169Y	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	L1170A	Neutral	0.016
NOTCH3	Q9UM47-1.2	L1170C	Neutral	0.017
NOTCH3	Q9UM47-1.2	L1170D	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	L1170E	Neutral	0.29
NOTCH3	Q9UM47-1.2	L1170F	Neutral	0.004
NOTCH3	Q9UM47-1.2	L1170G	Pathogenic	0.594
NOTCH3	Q9UM47-1.2	L1170H	Neutral	0.296
NOTCH3	Q9UM47-1.2	L1170I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1170K	Neutral	0.084
NOTCH3	Q9UM47-1.2	L1170M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1170N	Neutral	0.28
NOTCH3	Q9UM47-1.2	L1170P	Neutral	0.273
NOTCH3	Q9UM47-1.2	L1170Q	Neutral	0.083
NOTCH3	Q9UM47-1.2	L1170R	Neutral	0.08
NOTCH3	Q9UM47-1.2	L1170S	Neutral	0.072
NOTCH3	Q9UM47-1.2	L1170T	Neutral	0.018
NOTCH3	Q9UM47-1.2	L1170V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1170W	Neutral	0.075
NOTCH3	Q9UM47-1.2	L1170Y	Neutral	0.019
NOTCH3	Q9UM47-1.2	D1171A	Neutral	0.049
NOTCH3	Q9UM47-1.2	D1171C	Neutral	0.203
NOTCH3	Q9UM47-1.2	D1171E	Neutral	0.0
NOTCH3	Q9UM47-1.2	D1171F	Neutral	0.181
NOTCH3	Q9UM47-1.2	D1171G	Neutral	0.01
NOTCH3	Q9UM47-1.2	D1171H	Neutral	0.011
NOTCH3	Q9UM47-1.2	D1171I	Neutral	0.187
NOTCH3	Q9UM47-1.2	D1171K	Neutral	0.01
NOTCH3	Q9UM47-1.2	D1171L	Pathogenic	0.512
NOTCH3	Q9UM47-1.2	D1171M	Neutral	0.187
NOTCH3	Q9UM47-1.2	D1171N	Neutral	0.001
NOTCH3	Q9UM47-1.2	D1171P	Neutral	0.012
NOTCH3	Q9UM47-1.2	D1171Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	D1171R	Neutral	0.043
NOTCH3	Q9UM47-1.2	D1171S	Neutral	0.003
NOTCH3	Q9UM47-1.2	D1171T	Neutral	0.012
NOTCH3	Q9UM47-1.2	D1171V	Neutral	0.198
NOTCH3	Q9UM47-1.2	D1171W	Neutral	0.475
NOTCH3	Q9UM47-1.2	D1171Y	Neutral	0.177
NOTCH3	Q9UM47-1.2	S1172A	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1172C	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1172D	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1172E	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1172F	Neutral	0.008
NOTCH3	Q9UM47-1.2	S1172G	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1172H	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1172I	Neutral	0.008
NOTCH3	Q9UM47-1.2	S1172K	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1172L	Neutral	0.008
NOTCH3	Q9UM47-1.2	S1172M	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1172N	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1172P	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1172Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1172R	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1172T	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1172V	Neutral	0.009
NOTCH3	Q9UM47-1.2	S1172W	Neutral	0.032
NOTCH3	Q9UM47-1.2	S1172Y	Neutral	0.008
NOTCH3	Q9UM47-1.2	G1173A	Neutral	0.012
NOTCH3	Q9UM47-1.2	G1173C	Pathogenic	0.527
NOTCH3	Q9UM47-1.2	G1173D	Neutral	0.05
NOTCH3	Q9UM47-1.2	G1173E	Neutral	0.183
NOTCH3	Q9UM47-1.2	G1173F	Neutral	0.482
NOTCH3	Q9UM47-1.2	G1173H	Neutral	0.177
NOTCH3	Q9UM47-1.2	G1173I	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	G1173K	Neutral	0.169
NOTCH3	Q9UM47-1.2	G1173L	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	G1173M	Neutral	0.491
NOTCH3	Q9UM47-1.2	G1173N	Neutral	0.011
NOTCH3	Q9UM47-1.2	G1173P	Neutral	0.194
NOTCH3	Q9UM47-1.2	G1173Q	Neutral	0.179
NOTCH3	Q9UM47-1.2	G1173R	Neutral	0.162
NOTCH3	Q9UM47-1.2	G1173S	Neutral	0.012
NOTCH3	Q9UM47-1.2	G1173T	Neutral	0.192
NOTCH3	Q9UM47-1.2	G1173V	Pathogenic	0.509
NOTCH3	Q9UM47-1.2	G1173W	Neutral	0.155
NOTCH3	Q9UM47-1.2	G1173Y	Neutral	0.474
NOTCH3	Q9UM47-1.2	P1174A	Neutral	0.492
NOTCH3	Q9UM47-1.2	P1174C	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	P1174D	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	P1174E	Neutral	0.498
NOTCH3	Q9UM47-1.2	P1174F	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	P1174G	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	P1174H	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	P1174I	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	P1174K	Neutral	0.474
NOTCH3	Q9UM47-1.2	P1174L	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	P1174M	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	P1174N	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	P1174Q	Neutral	0.493
NOTCH3	Q9UM47-1.2	P1174R	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	P1174S	Neutral	0.499
NOTCH3	Q9UM47-1.2	P1174T	Pathogenic	0.512
NOTCH3	Q9UM47-1.2	P1174V	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	P1174W	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	P1174Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	R1175A	Neutral	0.1
NOTCH3	Q9UM47-1.2	R1175C	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	R1175D	Neutral	0.355
NOTCH3	Q9UM47-1.2	R1175E	Neutral	0.028
NOTCH3	Q9UM47-1.2	R1175F	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	R1175G	Neutral	0.319
NOTCH3	Q9UM47-1.2	R1175H	Neutral	0.029
NOTCH3	Q9UM47-1.2	R1175I	Pathogenic	0.744
NOTCH3	Q9UM47-1.2	R1175K	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1175L	Neutral	0.389
NOTCH3	Q9UM47-1.2	R1175M	Neutral	0.122
NOTCH3	Q9UM47-1.2	R1175N	Neutral	0.026
NOTCH3	Q9UM47-1.2	R1175P	Neutral	0.357
NOTCH3	Q9UM47-1.2	R1175Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	R1175S	Neutral	0.102
NOTCH3	Q9UM47-1.2	R1175T	Neutral	0.109
NOTCH3	Q9UM47-1.2	R1175V	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	R1175W	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	R1175Y	Neutral	0.404
NOTCH3	Q9UM47-1.2	C1176A	Neutral	0.472
NOTCH3	Q9UM47-1.2	C1176D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1176E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1176F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C1176G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1176H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1176I	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	C1176K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1176L	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	C1176M	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C1176N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1176P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1176Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1176R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1176S	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C1176T	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C1176V	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C1176W	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C1176Y	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	L1177A	Neutral	0.123
NOTCH3	Q9UM47-1.2	L1177C	Neutral	0.131
NOTCH3	Q9UM47-1.2	L1177D	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	L1177E	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	L1177F	Neutral	0.035
NOTCH3	Q9UM47-1.2	L1177G	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	L1177H	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	L1177I	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1177K	Neutral	0.436
NOTCH3	Q9UM47-1.2	L1177M	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1177N	Pathogenic	0.767
NOTCH3	Q9UM47-1.2	L1177P	Pathogenic	0.761
NOTCH3	Q9UM47-1.2	L1177Q	Neutral	0.436
NOTCH3	Q9UM47-1.2	L1177R	Neutral	0.424
NOTCH3	Q9UM47-1.2	L1177S	Neutral	0.397
NOTCH3	Q9UM47-1.2	L1177T	Neutral	0.135
NOTCH3	Q9UM47-1.2	L1177V	Neutral	0.008
NOTCH3	Q9UM47-1.2	L1177W	Neutral	0.406
NOTCH3	Q9UM47-1.2	L1177Y	Neutral	0.14
NOTCH3	Q9UM47-1.2	H1178A	Pathogenic	0.51
NOTCH3	Q9UM47-1.2	H1178C	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	H1178D	Neutral	0.201
NOTCH3	Q9UM47-1.2	H1178E	Neutral	0.056
NOTCH3	Q9UM47-1.2	H1178F	Neutral	0.209
NOTCH3	Q9UM47-1.2	H1178G	Neutral	0.492
NOTCH3	Q9UM47-1.2	H1178I	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	H1178K	Neutral	0.208
NOTCH3	Q9UM47-1.2	H1178L	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	H1178M	Pathogenic	0.555
NOTCH3	Q9UM47-1.2	H1178N	Neutral	0.012
NOTCH3	Q9UM47-1.2	H1178P	Pathogenic	0.533
NOTCH3	Q9UM47-1.2	H1178Q	Neutral	0.057
NOTCH3	Q9UM47-1.2	H1178R	Neutral	0.052
NOTCH3	Q9UM47-1.2	H1178S	Neutral	0.19
NOTCH3	Q9UM47-1.2	H1178T	Pathogenic	0.535
NOTCH3	Q9UM47-1.2	H1178V	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	H1178W	Pathogenic	0.52
NOTCH3	Q9UM47-1.2	H1178Y	Neutral	0.003
NOTCH3	Q9UM47-1.2	N1179A	Pathogenic	0.867
NOTCH3	Q9UM47-1.2	N1179C	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	N1179D	Neutral	0.07
NOTCH3	Q9UM47-1.2	N1179E	Neutral	0.25
NOTCH3	Q9UM47-1.2	N1179F	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	N1179G	Neutral	0.226
NOTCH3	Q9UM47-1.2	N1179H	Neutral	0.066
NOTCH3	Q9UM47-1.2	N1179I	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	N1179K	Neutral	0.232
NOTCH3	Q9UM47-1.2	N1179L	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	N1179M	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	N1179P	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	N1179Q	Neutral	0.246
NOTCH3	Q9UM47-1.2	N1179R	Neutral	0.223
NOTCH3	Q9UM47-1.2	N1179S	Neutral	0.066
NOTCH3	Q9UM47-1.2	N1179T	Neutral	0.258
NOTCH3	Q9UM47-1.2	N1179V	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	N1179W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	N1179Y	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	G1180A	Neutral	0.218
NOTCH3	Q9UM47-1.2	G1180C	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G1180D	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	G1180E	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	G1180F	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G1180H	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	G1180I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1180K	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	G1180L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1180M	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G1180N	Neutral	0.2
NOTCH3	Q9UM47-1.2	G1180P	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	G1180Q	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	G1180R	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	G1180S	Neutral	0.214
NOTCH3	Q9UM47-1.2	G1180T	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	G1180V	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G1180W	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	G1180Y	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	T1181A	Neutral	0.043
NOTCH3	Q9UM47-1.2	T1181C	Neutral	0.182
NOTCH3	Q9UM47-1.2	T1181D	Neutral	0.186
NOTCH3	Q9UM47-1.2	T1181E	Neutral	0.178
NOTCH3	Q9UM47-1.2	T1181F	Neutral	0.472
NOTCH3	Q9UM47-1.2	T1181G	Neutral	0.466
NOTCH3	Q9UM47-1.2	T1181H	Neutral	0.485
NOTCH3	Q9UM47-1.2	T1181I	Neutral	0.17
NOTCH3	Q9UM47-1.2	T1181K	Neutral	0.164
NOTCH3	Q9UM47-1.2	T1181L	Neutral	0.17
NOTCH3	Q9UM47-1.2	T1181M	Neutral	0.169
NOTCH3	Q9UM47-1.2	T1181N	Neutral	0.047
NOTCH3	Q9UM47-1.2	T1181P	Neutral	0.184
NOTCH3	Q9UM47-1.2	T1181Q	Neutral	0.174
NOTCH3	Q9UM47-1.2	T1181R	Neutral	0.157
NOTCH3	Q9UM47-1.2	T1181S	Neutral	0.01
NOTCH3	Q9UM47-1.2	T1181V	Neutral	0.046
NOTCH3	Q9UM47-1.2	T1181W	Neutral	0.446
NOTCH3	Q9UM47-1.2	T1181Y	Neutral	0.464
NOTCH3	Q9UM47-1.2	C1182A	Neutral	0.47
NOTCH3	Q9UM47-1.2	C1182D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1182E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1182F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C1182G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1182H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1182I	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C1182K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1182L	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C1182M	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	C1182N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1182P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1182Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1182R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1182S	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	C1182T	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C1182V	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	C1182W	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C1182Y	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	V1183A	Neutral	0.17
NOTCH3	Q9UM47-1.2	V1183C	Neutral	0.5
NOTCH3	Q9UM47-1.2	V1183D	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	V1183E	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	V1183F	Neutral	0.49
NOTCH3	Q9UM47-1.2	V1183G	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	V1183H	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	V1183I	Neutral	0.002
NOTCH3	Q9UM47-1.2	V1183K	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	V1183L	Neutral	0.046
NOTCH3	Q9UM47-1.2	V1183M	Neutral	0.046
NOTCH3	Q9UM47-1.2	V1183N	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	V1183P	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	V1183Q	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	V1183R	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	V1183S	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	V1183T	Neutral	0.185
NOTCH3	Q9UM47-1.2	V1183W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	V1183Y	Neutral	0.483
NOTCH3	Q9UM47-1.2	D1184A	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	D1184C	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1184E	Neutral	0.029
NOTCH3	Q9UM47-1.2	D1184F	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D1184G	Pathogenic	0.721
NOTCH3	Q9UM47-1.2	D1184H	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	D1184I	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D1184K	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	D1184L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1184M	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D1184N	Neutral	0.125
NOTCH3	Q9UM47-1.2	D1184P	Pathogenic	0.753
NOTCH3	Q9UM47-1.2	D1184Q	Neutral	0.379
NOTCH3	Q9UM47-1.2	D1184R	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	D1184S	Neutral	0.384
NOTCH3	Q9UM47-1.2	D1184T	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	D1184V	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1184W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1184Y	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L1185A	Neutral	0.015
NOTCH3	Q9UM47-1.2	L1185C	Neutral	0.017
NOTCH3	Q9UM47-1.2	L1185D	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	L1185E	Neutral	0.279
NOTCH3	Q9UM47-1.2	L1185F	Neutral	0.004
NOTCH3	Q9UM47-1.2	L1185G	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	L1185H	Neutral	0.284
NOTCH3	Q9UM47-1.2	L1185I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1185K	Neutral	0.08
NOTCH3	Q9UM47-1.2	L1185M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1185N	Neutral	0.269
NOTCH3	Q9UM47-1.2	L1185P	Neutral	0.262
NOTCH3	Q9UM47-1.2	L1185Q	Neutral	0.079
NOTCH3	Q9UM47-1.2	L1185R	Neutral	0.076
NOTCH3	Q9UM47-1.2	L1185S	Neutral	0.068
NOTCH3	Q9UM47-1.2	L1185T	Neutral	0.017
NOTCH3	Q9UM47-1.2	L1185V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1185W	Neutral	0.071
NOTCH3	Q9UM47-1.2	L1185Y	Neutral	0.018
NOTCH3	Q9UM47-1.2	V1186A	Neutral	0.187
NOTCH3	Q9UM47-1.2	V1186C	Pathogenic	0.529
NOTCH3	Q9UM47-1.2	V1186D	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	V1186E	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	V1186F	Pathogenic	0.519
NOTCH3	Q9UM47-1.2	V1186G	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	V1186H	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	V1186I	Neutral	0.003
NOTCH3	Q9UM47-1.2	V1186K	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	V1186L	Neutral	0.052
NOTCH3	Q9UM47-1.2	V1186M	Neutral	0.051
NOTCH3	Q9UM47-1.2	V1186N	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	V1186P	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	V1186Q	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	V1186R	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	V1186S	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	V1186T	Neutral	0.203
NOTCH3	Q9UM47-1.2	V1186W	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	V1186Y	Pathogenic	0.513
NOTCH3	Q9UM47-1.2	G1187A	Neutral	0.216
NOTCH3	Q9UM47-1.2	G1187C	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G1187D	Pathogenic	0.535
NOTCH3	Q9UM47-1.2	G1187E	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	G1187F	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	G1187H	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G1187I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1187K	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	G1187L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1187M	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G1187N	Neutral	0.198
NOTCH3	Q9UM47-1.2	G1187P	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	G1187Q	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	G1187R	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	G1187S	Neutral	0.212
NOTCH3	Q9UM47-1.2	G1187T	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	G1187V	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G1187W	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	G1187Y	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	G1188A	Neutral	0.144
NOTCH3	Q9UM47-1.2	G1188C	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	G1188D	Neutral	0.412
NOTCH3	Q9UM47-1.2	G1188E	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	G1188F	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	G1188H	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	G1188I	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	G1188K	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	G1188L	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	G1188M	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	G1188N	Neutral	0.131
NOTCH3	Q9UM47-1.2	G1188P	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	G1188Q	Pathogenic	0.744
NOTCH3	Q9UM47-1.2	G1188R	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	G1188S	Neutral	0.141
NOTCH3	Q9UM47-1.2	G1188T	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	G1188V	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	G1188W	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	G1188Y	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	F1189A	Pathogenic	0.619
NOTCH3	Q9UM47-1.2	F1189C	Pathogenic	0.635
NOTCH3	Q9UM47-1.2	F1189D	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	F1189E	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	F1189G	Pathogenic	0.873
NOTCH3	Q9UM47-1.2	F1189H	Neutral	0.303
NOTCH3	Q9UM47-1.2	F1189I	Neutral	0.088
NOTCH3	Q9UM47-1.2	F1189K	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	F1189L	Neutral	0.088
NOTCH3	Q9UM47-1.2	F1189M	Neutral	0.088
NOTCH3	Q9UM47-1.2	F1189N	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	F1189P	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	F1189Q	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	F1189R	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	F1189S	Pathogenic	0.625
NOTCH3	Q9UM47-1.2	F1189T	Pathogenic	0.643
NOTCH3	Q9UM47-1.2	F1189V	Neutral	0.291
NOTCH3	Q9UM47-1.2	F1189W	Neutral	0.02
NOTCH3	Q9UM47-1.2	F1189Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1190A	Neutral	0.056
NOTCH3	Q9UM47-1.2	R1190C	Pathogenic	0.572
NOTCH3	Q9UM47-1.2	R1190D	Neutral	0.228
NOTCH3	Q9UM47-1.2	R1190E	Neutral	0.015
NOTCH3	Q9UM47-1.2	R1190F	Pathogenic	0.62
NOTCH3	Q9UM47-1.2	R1190G	Neutral	0.201
NOTCH3	Q9UM47-1.2	R1190H	Neutral	0.016
NOTCH3	Q9UM47-1.2	R1190I	Pathogenic	0.61
NOTCH3	Q9UM47-1.2	R1190K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1190L	Neutral	0.255
NOTCH3	Q9UM47-1.2	R1190M	Neutral	0.07
NOTCH3	Q9UM47-1.2	R1190N	Neutral	0.014
NOTCH3	Q9UM47-1.2	R1190P	Neutral	0.23
NOTCH3	Q9UM47-1.2	R1190Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R1190S	Neutral	0.057
NOTCH3	Q9UM47-1.2	R1190T	Neutral	0.062
NOTCH3	Q9UM47-1.2	R1190V	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	R1190W	Pathogenic	0.619
NOTCH3	Q9UM47-1.2	R1190Y	Neutral	0.267
NOTCH3	Q9UM47-1.2	C1191A	Neutral	0.464
NOTCH3	Q9UM47-1.2	C1191D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1191E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1191F	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	C1191G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1191H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1191I	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	C1191K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1191L	Pathogenic	0.785
NOTCH3	Q9UM47-1.2	C1191M	Pathogenic	0.785
NOTCH3	Q9UM47-1.2	C1191N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1191P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1191Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1191R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1191S	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C1191T	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C1191V	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	C1191W	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	C1191Y	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	T1192A	Neutral	0.006
NOTCH3	Q9UM47-1.2	T1192C	Neutral	0.03
NOTCH3	Q9UM47-1.2	T1192D	Neutral	0.03
NOTCH3	Q9UM47-1.2	T1192E	Neutral	0.029
NOTCH3	Q9UM47-1.2	T1192F	Neutral	0.109
NOTCH3	Q9UM47-1.2	T1192G	Neutral	0.107
NOTCH3	Q9UM47-1.2	T1192H	Neutral	0.114
NOTCH3	Q9UM47-1.2	T1192I	Neutral	0.027
NOTCH3	Q9UM47-1.2	T1192K	Neutral	0.026
NOTCH3	Q9UM47-1.2	T1192L	Neutral	0.027
NOTCH3	Q9UM47-1.2	T1192M	Neutral	0.027
NOTCH3	Q9UM47-1.2	T1192N	Neutral	0.007
NOTCH3	Q9UM47-1.2	T1192P	Neutral	0.03
NOTCH3	Q9UM47-1.2	T1192Q	Neutral	0.028
NOTCH3	Q9UM47-1.2	T1192R	Neutral	0.025
NOTCH3	Q9UM47-1.2	T1192S	Neutral	0.001
NOTCH3	Q9UM47-1.2	T1192V	Neutral	0.007
NOTCH3	Q9UM47-1.2	T1192W	Neutral	0.099
NOTCH3	Q9UM47-1.2	T1192Y	Neutral	0.106
NOTCH3	Q9UM47-1.2	C1193A	Neutral	0.481
NOTCH3	Q9UM47-1.2	C1193D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1193E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1193F	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C1193G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1193H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1193I	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	C1193K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1193L	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	C1193M	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	C1193N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1193P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1193Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1193R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1193S	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	C1193T	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C1193V	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1193W	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	C1193Y	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	P1194A	Neutral	0.346
NOTCH3	Q9UM47-1.2	P1194C	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	P1194D	Neutral	0.367
NOTCH3	Q9UM47-1.2	P1194E	Neutral	0.351
NOTCH3	Q9UM47-1.2	P1194F	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	P1194G	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	P1194H	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	P1194I	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	P1194K	Neutral	0.329
NOTCH3	Q9UM47-1.2	P1194L	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	P1194M	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	P1194N	Pathogenic	0.721
NOTCH3	Q9UM47-1.2	P1194Q	Neutral	0.346
NOTCH3	Q9UM47-1.2	P1194R	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	P1194S	Neutral	0.352
NOTCH3	Q9UM47-1.2	P1194T	Neutral	0.364
NOTCH3	Q9UM47-1.2	P1194V	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	P1194W	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	P1194Y	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	P1195A	Pathogenic	0.508
NOTCH3	Q9UM47-1.2	P1195C	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	P1195D	Pathogenic	0.531
NOTCH3	Q9UM47-1.2	P1195E	Pathogenic	0.513
NOTCH3	Q9UM47-1.2	P1195F	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	P1195G	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	P1195H	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	P1195I	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	P1195K	Neutral	0.489
NOTCH3	Q9UM47-1.2	P1195L	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	P1195M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	P1195N	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	P1195Q	Pathogenic	0.508
NOTCH3	Q9UM47-1.2	P1195R	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	P1195S	Pathogenic	0.514
NOTCH3	Q9UM47-1.2	P1195T	Pathogenic	0.527
NOTCH3	Q9UM47-1.2	P1195V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	P1195W	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	P1195Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	G1196A	Neutral	0.209
NOTCH3	Q9UM47-1.2	G1196C	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1196D	Pathogenic	0.524
NOTCH3	Q9UM47-1.2	G1196E	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	G1196F	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	G1196H	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	G1196I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G1196K	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	G1196L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G1196M	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	G1196N	Neutral	0.191
NOTCH3	Q9UM47-1.2	G1196P	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	G1196Q	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	G1196R	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	G1196S	Neutral	0.205
NOTCH3	Q9UM47-1.2	G1196T	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	G1196V	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G1196W	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	G1196Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	Y1197A	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	Y1197C	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	Y1197D	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	Y1197E	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	Y1197F	Neutral	0.002
NOTCH3	Q9UM47-1.2	Y1197G	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	Y1197H	Neutral	0.009
NOTCH3	Q9UM47-1.2	Y1197I	Neutral	0.469
NOTCH3	Q9UM47-1.2	Y1197K	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	Y1197L	Neutral	0.469
NOTCH3	Q9UM47-1.2	Y1197M	Neutral	0.468
NOTCH3	Q9UM47-1.2	Y1197N	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	Y1197P	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	Y1197Q	Neutral	0.46
NOTCH3	Q9UM47-1.2	Y1197R	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	Y1197S	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	Y1197T	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	Y1197V	Neutral	0.449
NOTCH3	Q9UM47-1.2	Y1197W	Neutral	0.009
NOTCH3	Q9UM47-1.2	T1198A	Neutral	0.018
NOTCH3	Q9UM47-1.2	T1198C	Neutral	0.084
NOTCH3	Q9UM47-1.2	T1198D	Neutral	0.085
NOTCH3	Q9UM47-1.2	T1198E	Neutral	0.081
NOTCH3	Q9UM47-1.2	T1198F	Neutral	0.268
NOTCH3	Q9UM47-1.2	T1198G	Neutral	0.263
NOTCH3	Q9UM47-1.2	T1198H	Neutral	0.278
NOTCH3	Q9UM47-1.2	T1198I	Neutral	0.077
NOTCH3	Q9UM47-1.2	T1198K	Neutral	0.074
NOTCH3	Q9UM47-1.2	T1198L	Neutral	0.077
NOTCH3	Q9UM47-1.2	T1198M	Neutral	0.077
NOTCH3	Q9UM47-1.2	T1198N	Neutral	0.02
NOTCH3	Q9UM47-1.2	T1198P	Neutral	0.085
NOTCH3	Q9UM47-1.2	T1198Q	Neutral	0.079
NOTCH3	Q9UM47-1.2	T1198R	Neutral	0.071
NOTCH3	Q9UM47-1.2	T1198S	Neutral	0.004
NOTCH3	Q9UM47-1.2	T1198V	Neutral	0.019
NOTCH3	Q9UM47-1.2	T1198W	Neutral	0.248
NOTCH3	Q9UM47-1.2	T1198Y	Neutral	0.262
NOTCH3	Q9UM47-1.2	G1199A	Neutral	0.224
NOTCH3	Q9UM47-1.2	G1199C	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	G1199D	Pathogenic	0.545
NOTCH3	Q9UM47-1.2	G1199E	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	G1199F	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G1199H	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	G1199I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1199K	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	G1199L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1199M	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G1199N	Neutral	0.205
NOTCH3	Q9UM47-1.2	G1199P	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G1199Q	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	G1199R	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	G1199S	Neutral	0.219
NOTCH3	Q9UM47-1.2	G1199T	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	G1199V	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1199W	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	G1199Y	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	L1200A	Neutral	0.019
NOTCH3	Q9UM47-1.2	L1200C	Neutral	0.02
NOTCH3	Q9UM47-1.2	L1200D	Pathogenic	0.664
NOTCH3	Q9UM47-1.2	L1200E	Neutral	0.317
NOTCH3	Q9UM47-1.2	L1200F	Neutral	0.005
NOTCH3	Q9UM47-1.2	L1200G	Pathogenic	0.625
NOTCH3	Q9UM47-1.2	L1200H	Neutral	0.324
NOTCH3	Q9UM47-1.2	L1200I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1200K	Neutral	0.094
NOTCH3	Q9UM47-1.2	L1200M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1200N	Neutral	0.307
NOTCH3	Q9UM47-1.2	L1200P	Neutral	0.299
NOTCH3	Q9UM47-1.2	L1200Q	Neutral	0.094
NOTCH3	Q9UM47-1.2	L1200R	Neutral	0.09
NOTCH3	Q9UM47-1.2	L1200S	Neutral	0.081
NOTCH3	Q9UM47-1.2	L1200T	Neutral	0.021
NOTCH3	Q9UM47-1.2	L1200V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1200W	Neutral	0.084
NOTCH3	Q9UM47-1.2	L1200Y	Neutral	0.022
NOTCH3	Q9UM47-1.2	R1201A	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	R1201C	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	R1201D	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	R1201E	Neutral	0.378
NOTCH3	Q9UM47-1.2	R1201F	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	R1201G	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	R1201H	Neutral	0.388
NOTCH3	Q9UM47-1.2	R1201I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	R1201K	Neutral	0.031
NOTCH3	Q9UM47-1.2	R1201L	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	R1201M	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	R1201N	Neutral	0.367
NOTCH3	Q9UM47-1.2	R1201P	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	R1201Q	Neutral	0.12
NOTCH3	Q9UM47-1.2	R1201S	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	R1201T	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	R1201V	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	R1201W	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	R1201Y	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	C1202A	Neutral	0.481
NOTCH3	Q9UM47-1.2	C1202D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1202E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1202F	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C1202G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1202H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1202I	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	C1202K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1202L	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	C1202M	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	C1202N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1202P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1202Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1202R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1202S	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C1202T	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C1202V	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1202W	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	C1202Y	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	E1203A	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	E1203C	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	E1203D	Neutral	0.043
NOTCH3	Q9UM47-1.2	E1203F	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E1203G	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	E1203H	Neutral	0.491
NOTCH3	Q9UM47-1.2	E1203I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E1203K	Neutral	0.165
NOTCH3	Q9UM47-1.2	E1203L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E1203M	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	E1203N	Neutral	0.486
NOTCH3	Q9UM47-1.2	E1203P	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	E1203Q	Neutral	0.045
NOTCH3	Q9UM47-1.2	E1203R	Neutral	0.461
NOTCH3	Q9UM47-1.2	E1203S	Neutral	0.465
NOTCH3	Q9UM47-1.2	E1203T	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	E1203V	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	E1203W	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	E1203Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	A1204C	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1204D	Neutral	0.179
NOTCH3	Q9UM47-1.2	A1204E	Neutral	0.043
NOTCH3	Q9UM47-1.2	A1204F	Neutral	0.156
NOTCH3	Q9UM47-1.2	A1204G	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1204H	Neutral	0.163
NOTCH3	Q9UM47-1.2	A1204I	Neutral	0.041
NOTCH3	Q9UM47-1.2	A1204K	Neutral	0.039
NOTCH3	Q9UM47-1.2	A1204L	Neutral	0.04
NOTCH3	Q9UM47-1.2	A1204M	Neutral	0.04
NOTCH3	Q9UM47-1.2	A1204N	Neutral	0.176
NOTCH3	Q9UM47-1.2	A1204P	Neutral	0.046
NOTCH3	Q9UM47-1.2	A1204Q	Neutral	0.042
NOTCH3	Q9UM47-1.2	A1204R	Neutral	0.037
NOTCH3	Q9UM47-1.2	A1204S	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1204T	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1204V	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1204W	Neutral	0.43
NOTCH3	Q9UM47-1.2	A1204Y	Neutral	0.152
NOTCH3	Q9UM47-1.2	D1205A	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	D1205C	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1205E	Neutral	0.029
NOTCH3	Q9UM47-1.2	D1205F	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D1205G	Pathogenic	0.721
NOTCH3	Q9UM47-1.2	D1205H	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	D1205I	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D1205K	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	D1205L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1205M	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D1205N	Neutral	0.126
NOTCH3	Q9UM47-1.2	D1205P	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	D1205Q	Neutral	0.38
NOTCH3	Q9UM47-1.2	D1205R	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	D1205S	Neutral	0.385
NOTCH3	Q9UM47-1.2	D1205T	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	D1205V	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1205W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1205Y	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	I1206A	Pathogenic	0.588
NOTCH3	Q9UM47-1.2	I1206C	Pathogenic	0.604
NOTCH3	Q9UM47-1.2	I1206D	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	I1206E	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	I1206F	Neutral	0.27
NOTCH3	Q9UM47-1.2	I1206G	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	I1206H	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	I1206K	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	I1206L	Neutral	0.018
NOTCH3	Q9UM47-1.2	I1206M	Neutral	0.078
NOTCH3	Q9UM47-1.2	I1206N	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	I1206P	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	I1206Q	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	I1206R	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	I1206S	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	I1206T	Pathogenic	0.612
NOTCH3	Q9UM47-1.2	I1206V	Neutral	0.004
NOTCH3	Q9UM47-1.2	I1206W	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	I1206Y	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	N1207A	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	N1207C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N1207D	Neutral	0.137
NOTCH3	Q9UM47-1.2	N1207E	Neutral	0.412
NOTCH3	Q9UM47-1.2	N1207F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N1207G	Neutral	0.381
NOTCH3	Q9UM47-1.2	N1207H	Neutral	0.13
NOTCH3	Q9UM47-1.2	N1207I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N1207K	Neutral	0.389
NOTCH3	Q9UM47-1.2	N1207L	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N1207M	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	N1207P	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	N1207Q	Neutral	0.408
NOTCH3	Q9UM47-1.2	N1207R	Neutral	0.377
NOTCH3	Q9UM47-1.2	N1207S	Neutral	0.13
NOTCH3	Q9UM47-1.2	N1207T	Neutral	0.423
NOTCH3	Q9UM47-1.2	N1207V	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N1207W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N1207Y	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	E1208A	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	E1208C	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	E1208D	Neutral	0.041
NOTCH3	Q9UM47-1.2	E1208F	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	E1208G	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	E1208H	Neutral	0.482
NOTCH3	Q9UM47-1.2	E1208I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E1208K	Neutral	0.16
NOTCH3	Q9UM47-1.2	E1208L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E1208M	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	E1208N	Neutral	0.477
NOTCH3	Q9UM47-1.2	E1208P	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	E1208Q	Neutral	0.043
NOTCH3	Q9UM47-1.2	E1208R	Neutral	0.452
NOTCH3	Q9UM47-1.2	E1208S	Neutral	0.456
NOTCH3	Q9UM47-1.2	E1208T	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	E1208V	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	E1208W	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	E1208Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C1209A	Neutral	0.476
NOTCH3	Q9UM47-1.2	C1209D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1209E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1209F	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	C1209G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1209H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1209I	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	C1209K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1209L	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	C1209M	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	C1209N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1209P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1209Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1209R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1209S	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C1209T	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	C1209V	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C1209W	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	C1209Y	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	R1210A	Neutral	0.066
NOTCH3	Q9UM47-1.2	R1210C	Pathogenic	0.613
NOTCH3	Q9UM47-1.2	R1210D	Neutral	0.259
NOTCH3	Q9UM47-1.2	R1210E	Neutral	0.018
NOTCH3	Q9UM47-1.2	R1210F	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	R1210G	Neutral	0.23
NOTCH3	Q9UM47-1.2	R1210H	Neutral	0.019
NOTCH3	Q9UM47-1.2	R1210I	Pathogenic	0.649
NOTCH3	Q9UM47-1.2	R1210K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1210L	Neutral	0.288
NOTCH3	Q9UM47-1.2	R1210M	Neutral	0.081
NOTCH3	Q9UM47-1.2	R1210N	Neutral	0.017
NOTCH3	Q9UM47-1.2	R1210P	Neutral	0.261
NOTCH3	Q9UM47-1.2	R1210Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	R1210S	Neutral	0.067
NOTCH3	Q9UM47-1.2	R1210T	Neutral	0.072
NOTCH3	Q9UM47-1.2	R1210V	Pathogenic	0.631
NOTCH3	Q9UM47-1.2	R1210W	Pathogenic	0.657
NOTCH3	Q9UM47-1.2	R1210Y	Neutral	0.301
NOTCH3	Q9UM47-1.2	S1211A	Neutral	0.054
NOTCH3	Q9UM47-1.2	S1211C	Pathogenic	0.534
NOTCH3	Q9UM47-1.2	S1211D	Neutral	0.198
NOTCH3	Q9UM47-1.2	S1211E	Neutral	0.187
NOTCH3	Q9UM47-1.2	S1211F	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	S1211G	Neutral	0.193
NOTCH3	Q9UM47-1.2	S1211H	Pathogenic	0.502
NOTCH3	Q9UM47-1.2	S1211I	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	S1211K	Neutral	0.173
NOTCH3	Q9UM47-1.2	S1211L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	S1211M	Neutral	0.498
NOTCH3	Q9UM47-1.2	S1211N	Neutral	0.05
NOTCH3	Q9UM47-1.2	S1211P	Pathogenic	0.53
NOTCH3	Q9UM47-1.2	S1211Q	Neutral	0.183
NOTCH3	Q9UM47-1.2	S1211R	Neutral	0.474
NOTCH3	Q9UM47-1.2	S1211T	Neutral	0.051
NOTCH3	Q9UM47-1.2	S1211V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	S1211W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	S1211Y	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	G1212A	Neutral	0.005
NOTCH3	Q9UM47-1.2	G1212C	Neutral	0.309
NOTCH3	Q9UM47-1.2	G1212D	Neutral	0.021
NOTCH3	Q9UM47-1.2	G1212E	Neutral	0.082
NOTCH3	Q9UM47-1.2	G1212F	Neutral	0.272
NOTCH3	Q9UM47-1.2	G1212H	Neutral	0.079
NOTCH3	Q9UM47-1.2	G1212I	Pathogenic	0.639
NOTCH3	Q9UM47-1.2	G1212K	Neutral	0.075
NOTCH3	Q9UM47-1.2	G1212L	Pathogenic	0.639
NOTCH3	Q9UM47-1.2	G1212M	Neutral	0.279
NOTCH3	Q9UM47-1.2	G1212N	Neutral	0.005
NOTCH3	Q9UM47-1.2	G1212P	Neutral	0.088
NOTCH3	Q9UM47-1.2	G1212Q	Neutral	0.081
NOTCH3	Q9UM47-1.2	G1212R	Neutral	0.072
NOTCH3	Q9UM47-1.2	G1212S	Neutral	0.005
NOTCH3	Q9UM47-1.2	G1212T	Neutral	0.087
NOTCH3	Q9UM47-1.2	G1212V	Neutral	0.294
NOTCH3	Q9UM47-1.2	G1212W	Neutral	0.069
NOTCH3	Q9UM47-1.2	G1212Y	Neutral	0.266
NOTCH3	Q9UM47-1.2	A1213C	Neutral	0.008
NOTCH3	Q9UM47-1.2	A1213D	Neutral	0.146
NOTCH3	Q9UM47-1.2	A1213E	Neutral	0.034
NOTCH3	Q9UM47-1.2	A1213F	Neutral	0.127
NOTCH3	Q9UM47-1.2	A1213G	Neutral	0.008
NOTCH3	Q9UM47-1.2	A1213H	Neutral	0.133
NOTCH3	Q9UM47-1.2	A1213I	Neutral	0.032
NOTCH3	Q9UM47-1.2	A1213K	Neutral	0.031
NOTCH3	Q9UM47-1.2	A1213L	Neutral	0.032
NOTCH3	Q9UM47-1.2	A1213M	Neutral	0.032
NOTCH3	Q9UM47-1.2	A1213N	Neutral	0.144
NOTCH3	Q9UM47-1.2	A1213P	Neutral	0.036
NOTCH3	Q9UM47-1.2	A1213Q	Neutral	0.033
NOTCH3	Q9UM47-1.2	A1213R	Neutral	0.029
NOTCH3	Q9UM47-1.2	A1213S	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1213T	Neutral	0.008
NOTCH3	Q9UM47-1.2	A1213V	Neutral	0.008
NOTCH3	Q9UM47-1.2	A1213W	Neutral	0.373
NOTCH3	Q9UM47-1.2	A1213Y	Neutral	0.124
NOTCH3	Q9UM47-1.2	C1214A	Neutral	0.473
NOTCH3	Q9UM47-1.2	C1214D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1214E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1214F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C1214G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1214H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1214I	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	C1214K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1214L	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	C1214M	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	C1214N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1214P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1214Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1214R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1214S	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1214T	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C1214V	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C1214W	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C1214Y	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	H1215A	Neutral	0.326
NOTCH3	Q9UM47-1.2	H1215C	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	H1215D	Neutral	0.105
NOTCH3	Q9UM47-1.2	H1215E	Neutral	0.027
NOTCH3	Q9UM47-1.2	H1215F	Neutral	0.109
NOTCH3	Q9UM47-1.2	H1215G	Neutral	0.31
NOTCH3	Q9UM47-1.2	H1215I	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	H1215K	Neutral	0.109
NOTCH3	Q9UM47-1.2	H1215L	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	H1215M	Neutral	0.367
NOTCH3	Q9UM47-1.2	H1215N	Neutral	0.006
NOTCH3	Q9UM47-1.2	H1215P	Neutral	0.347
NOTCH3	Q9UM47-1.2	H1215Q	Neutral	0.027
NOTCH3	Q9UM47-1.2	H1215R	Neutral	0.025
NOTCH3	Q9UM47-1.2	H1215S	Neutral	0.098
NOTCH3	Q9UM47-1.2	H1215T	Neutral	0.349
NOTCH3	Q9UM47-1.2	H1215V	Pathogenic	0.72
NOTCH3	Q9UM47-1.2	H1215W	Neutral	0.335
NOTCH3	Q9UM47-1.2	H1215Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1216C	Neutral	0.015
NOTCH3	Q9UM47-1.2	A1216D	Neutral	0.237
NOTCH3	Q9UM47-1.2	A1216E	Neutral	0.06
NOTCH3	Q9UM47-1.2	A1216F	Neutral	0.208
NOTCH3	Q9UM47-1.2	A1216G	Neutral	0.015
NOTCH3	Q9UM47-1.2	A1216H	Neutral	0.217
NOTCH3	Q9UM47-1.2	A1216I	Neutral	0.057
NOTCH3	Q9UM47-1.2	A1216K	Neutral	0.054
NOTCH3	Q9UM47-1.2	A1216L	Neutral	0.057
NOTCH3	Q9UM47-1.2	A1216M	Neutral	0.056
NOTCH3	Q9UM47-1.2	A1216N	Neutral	0.233
NOTCH3	Q9UM47-1.2	A1216P	Neutral	0.064
NOTCH3	Q9UM47-1.2	A1216Q	Neutral	0.058
NOTCH3	Q9UM47-1.2	A1216R	Neutral	0.052
NOTCH3	Q9UM47-1.2	A1216S	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1216T	Neutral	0.015
NOTCH3	Q9UM47-1.2	A1216V	Neutral	0.014
NOTCH3	Q9UM47-1.2	A1216W	Pathogenic	0.518
NOTCH3	Q9UM47-1.2	A1216Y	Neutral	0.203
NOTCH3	Q9UM47-1.2	A1217C	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1217D	Neutral	0.075
NOTCH3	Q9UM47-1.2	A1217E	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1217F	Neutral	0.064
NOTCH3	Q9UM47-1.2	A1217G	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1217H	Neutral	0.068
NOTCH3	Q9UM47-1.2	A1217I	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1217K	Neutral	0.015
NOTCH3	Q9UM47-1.2	A1217L	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1217M	Neutral	0.015
NOTCH3	Q9UM47-1.2	A1217N	Neutral	0.074
NOTCH3	Q9UM47-1.2	A1217P	Neutral	0.018
NOTCH3	Q9UM47-1.2	A1217Q	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1217R	Neutral	0.014
NOTCH3	Q9UM47-1.2	A1217S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1217T	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1217V	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1217W	Neutral	0.22
NOTCH3	Q9UM47-1.2	A1217Y	Neutral	0.063
NOTCH3	Q9UM47-1.2	H1218A	Neutral	0.412
NOTCH3	Q9UM47-1.2	H1218C	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	H1218D	Neutral	0.145
NOTCH3	Q9UM47-1.2	H1218E	Neutral	0.038
NOTCH3	Q9UM47-1.2	H1218F	Neutral	0.151
NOTCH3	Q9UM47-1.2	H1218G	Neutral	0.395
NOTCH3	Q9UM47-1.2	H1218I	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	H1218K	Neutral	0.15
NOTCH3	Q9UM47-1.2	H1218L	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	H1218M	Neutral	0.457
NOTCH3	Q9UM47-1.2	H1218N	Neutral	0.008
NOTCH3	Q9UM47-1.2	H1218P	Neutral	0.435
NOTCH3	Q9UM47-1.2	H1218Q	Neutral	0.039
NOTCH3	Q9UM47-1.2	H1218R	Neutral	0.036
NOTCH3	Q9UM47-1.2	H1218S	Neutral	0.136
NOTCH3	Q9UM47-1.2	H1218T	Neutral	0.437
NOTCH3	Q9UM47-1.2	H1218V	Pathogenic	0.788
NOTCH3	Q9UM47-1.2	H1218W	Neutral	0.422
NOTCH3	Q9UM47-1.2	H1218Y	Neutral	0.002
NOTCH3	Q9UM47-1.2	T1219A	Neutral	0.115
NOTCH3	Q9UM47-1.2	T1219C	Neutral	0.391
NOTCH3	Q9UM47-1.2	T1219D	Neutral	0.396
NOTCH3	Q9UM47-1.2	T1219E	Neutral	0.383
NOTCH3	Q9UM47-1.2	T1219F	Pathogenic	0.72
NOTCH3	Q9UM47-1.2	T1219G	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	T1219H	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	T1219I	Neutral	0.371
NOTCH3	Q9UM47-1.2	T1219K	Neutral	0.361
NOTCH3	Q9UM47-1.2	T1219L	Neutral	0.371
NOTCH3	Q9UM47-1.2	T1219M	Neutral	0.37
NOTCH3	Q9UM47-1.2	T1219N	Neutral	0.125
NOTCH3	Q9UM47-1.2	T1219P	Neutral	0.394
NOTCH3	Q9UM47-1.2	T1219Q	Neutral	0.378
NOTCH3	Q9UM47-1.2	T1219R	Neutral	0.349
NOTCH3	Q9UM47-1.2	T1219S	Neutral	0.029
NOTCH3	Q9UM47-1.2	T1219V	Neutral	0.122
NOTCH3	Q9UM47-1.2	T1219W	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	T1219Y	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	R1220A	Neutral	0.041
NOTCH3	Q9UM47-1.2	R1220C	Neutral	0.492
NOTCH3	Q9UM47-1.2	R1220D	Neutral	0.176
NOTCH3	Q9UM47-1.2	R1220E	Neutral	0.011
NOTCH3	Q9UM47-1.2	R1220F	Pathogenic	0.541
NOTCH3	Q9UM47-1.2	R1220G	Neutral	0.154
NOTCH3	Q9UM47-1.2	R1220H	Neutral	0.011
NOTCH3	Q9UM47-1.2	R1220I	Pathogenic	0.53
NOTCH3	Q9UM47-1.2	R1220K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1220L	Neutral	0.198
NOTCH3	Q9UM47-1.2	R1220M	Neutral	0.051
NOTCH3	Q9UM47-1.2	R1220N	Neutral	0.01
NOTCH3	Q9UM47-1.2	R1220P	Neutral	0.177
NOTCH3	Q9UM47-1.2	R1220Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1220S	Neutral	0.042
NOTCH3	Q9UM47-1.2	R1220T	Neutral	0.046
NOTCH3	Q9UM47-1.2	R1220V	Pathogenic	0.511
NOTCH3	Q9UM47-1.2	R1220W	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	R1220Y	Neutral	0.208
NOTCH3	Q9UM47-1.2	D1221A	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	D1221C	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	D1221E	Neutral	0.005
NOTCH3	Q9UM47-1.2	D1221F	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	D1221G	Neutral	0.313
NOTCH3	Q9UM47-1.2	D1221H	Neutral	0.326
NOTCH3	Q9UM47-1.2	D1221I	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	D1221K	Neutral	0.311
NOTCH3	Q9UM47-1.2	D1221L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	D1221M	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	D1221N	Neutral	0.025
NOTCH3	Q9UM47-1.2	D1221P	Neutral	0.35
NOTCH3	Q9UM47-1.2	D1221Q	Neutral	0.097
NOTCH3	Q9UM47-1.2	D1221R	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	D1221S	Neutral	0.099
NOTCH3	Q9UM47-1.2	D1221T	Neutral	0.348
NOTCH3	Q9UM47-1.2	D1221V	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	D1221W	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	D1221Y	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	C1222A	Neutral	0.473
NOTCH3	Q9UM47-1.2	C1222D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1222E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1222F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C1222G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1222H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1222I	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	C1222K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1222L	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	C1222M	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	C1222N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1222P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1222Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1222R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1222S	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1222T	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C1222V	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C1222W	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C1222Y	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	L1223A	Neutral	0.026
NOTCH3	Q9UM47-1.2	L1223C	Neutral	0.027
NOTCH3	Q9UM47-1.2	L1223D	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	L1223E	Neutral	0.393
NOTCH3	Q9UM47-1.2	L1223F	Neutral	0.007
NOTCH3	Q9UM47-1.2	L1223G	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	L1223H	Neutral	0.4
NOTCH3	Q9UM47-1.2	L1223I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1223K	Neutral	0.127
NOTCH3	Q9UM47-1.2	L1223M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1223N	Neutral	0.381
NOTCH3	Q9UM47-1.2	L1223P	Neutral	0.373
NOTCH3	Q9UM47-1.2	L1223Q	Neutral	0.126
NOTCH3	Q9UM47-1.2	L1223R	Neutral	0.121
NOTCH3	Q9UM47-1.2	L1223S	Neutral	0.11
NOTCH3	Q9UM47-1.2	L1223T	Neutral	0.028
NOTCH3	Q9UM47-1.2	L1223V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1223W	Neutral	0.113
NOTCH3	Q9UM47-1.2	L1223Y	Neutral	0.03
NOTCH3	Q9UM47-1.2	Q1224A	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	Q1224C	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	Q1224D	Neutral	0.467
NOTCH3	Q9UM47-1.2	Q1224E	Neutral	0.043
NOTCH3	Q9UM47-1.2	Q1224F	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	Q1224G	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	Q1224H	Neutral	0.485
NOTCH3	Q9UM47-1.2	Q1224I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	Q1224K	Neutral	0.163
NOTCH3	Q9UM47-1.2	Q1224L	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	Q1224M	Neutral	0.481
NOTCH3	Q9UM47-1.2	Q1224N	Neutral	0.471
NOTCH3	Q9UM47-1.2	Q1224P	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	Q1224R	Neutral	0.156
NOTCH3	Q9UM47-1.2	Q1224S	Neutral	0.449
NOTCH3	Q9UM47-1.2	Q1224T	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	Q1224V	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	Q1224W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	Q1224Y	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	D1225A	Neutral	0.102
NOTCH3	Q9UM47-1.2	D1225C	Neutral	0.36
NOTCH3	Q9UM47-1.2	D1225E	Neutral	0.0
NOTCH3	Q9UM47-1.2	D1225F	Neutral	0.327
NOTCH3	Q9UM47-1.2	D1225G	Neutral	0.023
NOTCH3	Q9UM47-1.2	D1225H	Neutral	0.024
NOTCH3	Q9UM47-1.2	D1225I	Neutral	0.337
NOTCH3	Q9UM47-1.2	D1225K	Neutral	0.023
NOTCH3	Q9UM47-1.2	D1225L	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	D1225M	Neutral	0.336
NOTCH3	Q9UM47-1.2	D1225N	Neutral	0.001
NOTCH3	Q9UM47-1.2	D1225P	Neutral	0.027
NOTCH3	Q9UM47-1.2	D1225Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	D1225R	Neutral	0.091
NOTCH3	Q9UM47-1.2	D1225S	Neutral	0.006
NOTCH3	Q9UM47-1.2	D1225T	Neutral	0.027
NOTCH3	Q9UM47-1.2	D1225V	Neutral	0.352
NOTCH3	Q9UM47-1.2	D1225W	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	D1225Y	Neutral	0.321
NOTCH3	Q9UM47-1.2	P1226A	Neutral	0.02
NOTCH3	Q9UM47-1.2	P1226C	Neutral	0.309
NOTCH3	Q9UM47-1.2	P1226D	Neutral	0.022
NOTCH3	Q9UM47-1.2	P1226E	Neutral	0.02
NOTCH3	Q9UM47-1.2	P1226F	Pathogenic	0.637
NOTCH3	Q9UM47-1.2	P1226G	Neutral	0.079
NOTCH3	Q9UM47-1.2	P1226H	Neutral	0.083
NOTCH3	Q9UM47-1.2	P1226I	Neutral	0.287
NOTCH3	Q9UM47-1.2	P1226K	Neutral	0.018
NOTCH3	Q9UM47-1.2	P1226L	Neutral	0.286
NOTCH3	Q9UM47-1.2	P1226M	Neutral	0.081
NOTCH3	Q9UM47-1.2	P1226N	Neutral	0.09
NOTCH3	Q9UM47-1.2	P1226Q	Neutral	0.02
NOTCH3	Q9UM47-1.2	P1226R	Neutral	0.075
NOTCH3	Q9UM47-1.2	P1226S	Neutral	0.02
NOTCH3	Q9UM47-1.2	P1226T	Neutral	0.021
NOTCH3	Q9UM47-1.2	P1226V	Neutral	0.086
NOTCH3	Q9UM47-1.2	P1226W	Pathogenic	0.612
NOTCH3	Q9UM47-1.2	P1226Y	Neutral	0.272
NOTCH3	Q9UM47-1.2	G1227A	Neutral	0.006
NOTCH3	Q9UM47-1.2	G1227C	Neutral	0.358
NOTCH3	Q9UM47-1.2	G1227D	Neutral	0.026
NOTCH3	Q9UM47-1.2	G1227E	Neutral	0.1
NOTCH3	Q9UM47-1.2	G1227F	Neutral	0.317
NOTCH3	Q9UM47-1.2	G1227H	Neutral	0.097
NOTCH3	Q9UM47-1.2	G1227I	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	G1227K	Neutral	0.092
NOTCH3	Q9UM47-1.2	G1227L	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	G1227M	Neutral	0.325
NOTCH3	Q9UM47-1.2	G1227N	Neutral	0.006
NOTCH3	Q9UM47-1.2	G1227P	Neutral	0.107
NOTCH3	Q9UM47-1.2	G1227Q	Neutral	0.098
NOTCH3	Q9UM47-1.2	G1227R	Neutral	0.088
NOTCH3	Q9UM47-1.2	G1227S	Neutral	0.006
NOTCH3	Q9UM47-1.2	G1227T	Neutral	0.106
NOTCH3	Q9UM47-1.2	G1227V	Neutral	0.342
NOTCH3	Q9UM47-1.2	G1227W	Neutral	0.084
NOTCH3	Q9UM47-1.2	G1227Y	Neutral	0.311
NOTCH3	Q9UM47-1.2	G1228A	Neutral	0.005
NOTCH3	Q9UM47-1.2	G1228C	Neutral	0.318
NOTCH3	Q9UM47-1.2	G1228D	Neutral	0.022
NOTCH3	Q9UM47-1.2	G1228E	Neutral	0.085
NOTCH3	Q9UM47-1.2	G1228F	Neutral	0.28
NOTCH3	Q9UM47-1.2	G1228H	Neutral	0.082
NOTCH3	Q9UM47-1.2	G1228I	Pathogenic	0.649
NOTCH3	Q9UM47-1.2	G1228K	Neutral	0.078
NOTCH3	Q9UM47-1.2	G1228L	Pathogenic	0.648
NOTCH3	Q9UM47-1.2	G1228M	Neutral	0.288
NOTCH3	Q9UM47-1.2	G1228N	Neutral	0.005
NOTCH3	Q9UM47-1.2	G1228P	Neutral	0.091
NOTCH3	Q9UM47-1.2	G1228Q	Neutral	0.084
NOTCH3	Q9UM47-1.2	G1228R	Neutral	0.075
NOTCH3	Q9UM47-1.2	G1228S	Neutral	0.005
NOTCH3	Q9UM47-1.2	G1228T	Neutral	0.09
NOTCH3	Q9UM47-1.2	G1228V	Neutral	0.303
NOTCH3	Q9UM47-1.2	G1228W	Neutral	0.071
NOTCH3	Q9UM47-1.2	G1228Y	Neutral	0.274
NOTCH3	Q9UM47-1.2	G1229A	Neutral	0.001
NOTCH3	Q9UM47-1.2	G1229C	Neutral	0.107
NOTCH3	Q9UM47-1.2	G1229D	Neutral	0.006
NOTCH3	Q9UM47-1.2	G1229E	Neutral	0.024
NOTCH3	Q9UM47-1.2	G1229F	Neutral	0.091
NOTCH3	Q9UM47-1.2	G1229H	Neutral	0.023
NOTCH3	Q9UM47-1.2	G1229I	Neutral	0.323
NOTCH3	Q9UM47-1.2	G1229K	Neutral	0.021
NOTCH3	Q9UM47-1.2	G1229L	Neutral	0.322
NOTCH3	Q9UM47-1.2	G1229M	Neutral	0.094
NOTCH3	Q9UM47-1.2	G1229N	Neutral	0.001
NOTCH3	Q9UM47-1.2	G1229P	Neutral	0.025
NOTCH3	Q9UM47-1.2	G1229Q	Neutral	0.023
NOTCH3	Q9UM47-1.2	G1229R	Neutral	0.02
NOTCH3	Q9UM47-1.2	G1229S	Neutral	0.001
NOTCH3	Q9UM47-1.2	G1229T	Neutral	0.025
NOTCH3	Q9UM47-1.2	G1229V	Neutral	0.101
NOTCH3	Q9UM47-1.2	G1229W	Neutral	0.019
NOTCH3	Q9UM47-1.2	G1229Y	Neutral	0.089
NOTCH3	Q9UM47-1.2	F1230A	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	F1230C	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	F1230D	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	F1230E	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	F1230G	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	F1230H	Pathogenic	0.519
NOTCH3	Q9UM47-1.2	F1230I	Neutral	0.193
NOTCH3	Q9UM47-1.2	F1230K	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	F1230L	Neutral	0.193
NOTCH3	Q9UM47-1.2	F1230M	Neutral	0.194
NOTCH3	Q9UM47-1.2	F1230N	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	F1230P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	F1230Q	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	F1230R	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	F1230S	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	F1230T	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	F1230V	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	F1230W	Neutral	0.047
NOTCH3	Q9UM47-1.2	F1230Y	Neutral	0.003
NOTCH3	Q9UM47-1.2	R1231A	Neutral	0.057
NOTCH3	Q9UM47-1.2	R1231C	Pathogenic	0.576
NOTCH3	Q9UM47-1.2	R1231D	Neutral	0.231
NOTCH3	Q9UM47-1.2	R1231E	Neutral	0.015
NOTCH3	Q9UM47-1.2	R1231F	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	R1231G	Neutral	0.204
NOTCH3	Q9UM47-1.2	R1231H	Neutral	0.016
NOTCH3	Q9UM47-1.2	R1231I	Pathogenic	0.613
NOTCH3	Q9UM47-1.2	R1231K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1231L	Neutral	0.258
NOTCH3	Q9UM47-1.2	R1231M	Neutral	0.071
NOTCH3	Q9UM47-1.2	R1231N	Neutral	0.015
NOTCH3	Q9UM47-1.2	R1231P	Neutral	0.232
NOTCH3	Q9UM47-1.2	R1231Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R1231S	Neutral	0.058
NOTCH3	Q9UM47-1.2	R1231T	Neutral	0.063
NOTCH3	Q9UM47-1.2	R1231V	Pathogenic	0.595
NOTCH3	Q9UM47-1.2	R1231W	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	R1231Y	Neutral	0.27
NOTCH3	Q9UM47-1.2	C1232A	Neutral	0.482
NOTCH3	Q9UM47-1.2	C1232D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1232E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1232F	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C1232G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1232H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1232I	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	C1232K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1232L	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	C1232M	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	C1232N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1232P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1232Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1232R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1232S	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C1232T	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C1232V	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1232W	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	C1232Y	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	L1233A	Neutral	0.01
NOTCH3	Q9UM47-1.2	L1233C	Neutral	0.011
NOTCH3	Q9UM47-1.2	L1233D	Pathogenic	0.522
NOTCH3	Q9UM47-1.2	L1233E	Neutral	0.204
NOTCH3	Q9UM47-1.2	L1233F	Neutral	0.003
NOTCH3	Q9UM47-1.2	L1233G	Neutral	0.478
NOTCH3	Q9UM47-1.2	L1233H	Neutral	0.209
NOTCH3	Q9UM47-1.2	L1233I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1233K	Neutral	0.054
NOTCH3	Q9UM47-1.2	L1233M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1233N	Neutral	0.196
NOTCH3	Q9UM47-1.2	L1233P	Neutral	0.191
NOTCH3	Q9UM47-1.2	L1233Q	Neutral	0.054
NOTCH3	Q9UM47-1.2	L1233R	Neutral	0.052
NOTCH3	Q9UM47-1.2	L1233S	Neutral	0.047
NOTCH3	Q9UM47-1.2	L1233T	Neutral	0.011
NOTCH3	Q9UM47-1.2	L1233V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1233W	Neutral	0.048
NOTCH3	Q9UM47-1.2	L1233Y	Neutral	0.012
NOTCH3	Q9UM47-1.2	C1234A	Neutral	0.475
NOTCH3	Q9UM47-1.2	C1234D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1234E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1234F	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	C1234G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1234H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1234I	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	C1234K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1234L	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	C1234M	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	C1234N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1234P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1234Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1234R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1234S	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C1234T	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	C1234V	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C1234W	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	C1234Y	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	H1235A	Neutral	0.281
NOTCH3	Q9UM47-1.2	H1235C	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	H1235D	Neutral	0.087
NOTCH3	Q9UM47-1.2	H1235E	Neutral	0.022
NOTCH3	Q9UM47-1.2	H1235F	Neutral	0.09
NOTCH3	Q9UM47-1.2	H1235G	Neutral	0.267
NOTCH3	Q9UM47-1.2	H1235I	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	H1235K	Neutral	0.09
NOTCH3	Q9UM47-1.2	H1235L	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	H1235M	Neutral	0.32
NOTCH3	Q9UM47-1.2	H1235N	Neutral	0.005
NOTCH3	Q9UM47-1.2	H1235P	Neutral	0.3
NOTCH3	Q9UM47-1.2	H1235Q	Neutral	0.022
NOTCH3	Q9UM47-1.2	H1235R	Neutral	0.02
NOTCH3	Q9UM47-1.2	H1235S	Neutral	0.081
NOTCH3	Q9UM47-1.2	H1235T	Neutral	0.302
NOTCH3	Q9UM47-1.2	H1235V	Pathogenic	0.675
NOTCH3	Q9UM47-1.2	H1235W	Neutral	0.289
NOTCH3	Q9UM47-1.2	H1235Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1236C	Neutral	0.008
NOTCH3	Q9UM47-1.2	A1236D	Neutral	0.135
NOTCH3	Q9UM47-1.2	A1236E	Neutral	0.031
NOTCH3	Q9UM47-1.2	A1236F	Neutral	0.116
NOTCH3	Q9UM47-1.2	A1236G	Neutral	0.008
NOTCH3	Q9UM47-1.2	A1236H	Neutral	0.122
NOTCH3	Q9UM47-1.2	A1236I	Neutral	0.029
NOTCH3	Q9UM47-1.2	A1236K	Neutral	0.028
NOTCH3	Q9UM47-1.2	A1236L	Neutral	0.029
NOTCH3	Q9UM47-1.2	A1236M	Neutral	0.029
NOTCH3	Q9UM47-1.2	A1236N	Neutral	0.132
NOTCH3	Q9UM47-1.2	A1236P	Neutral	0.033
NOTCH3	Q9UM47-1.2	A1236Q	Neutral	0.03
NOTCH3	Q9UM47-1.2	A1236R	Neutral	0.027
NOTCH3	Q9UM47-1.2	A1236S	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1236T	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1236V	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1236W	Neutral	0.351
NOTCH3	Q9UM47-1.2	A1236Y	Neutral	0.113
NOTCH3	Q9UM47-1.2	G1237A	Neutral	0.08
NOTCH3	Q9UM47-1.2	G1237C	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	G1237D	Neutral	0.266
NOTCH3	Q9UM47-1.2	G1237E	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	G1237F	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	G1237H	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	G1237I	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	G1237K	Pathogenic	0.583
NOTCH3	Q9UM47-1.2	G1237L	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	G1237M	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	G1237N	Neutral	0.073
NOTCH3	Q9UM47-1.2	G1237P	Pathogenic	0.624
NOTCH3	Q9UM47-1.2	G1237Q	Pathogenic	0.601
NOTCH3	Q9UM47-1.2	G1237R	Pathogenic	0.571
NOTCH3	Q9UM47-1.2	G1237S	Neutral	0.078
NOTCH3	Q9UM47-1.2	G1237T	Pathogenic	0.62
NOTCH3	Q9UM47-1.2	G1237V	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	G1237W	Pathogenic	0.559
NOTCH3	Q9UM47-1.2	G1237Y	Pathogenic	0.861
NOTCH3	Q9UM47-1.2	F1238A	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	F1238C	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	F1238D	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	F1238E	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	F1238G	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	F1238H	Pathogenic	0.596
NOTCH3	Q9UM47-1.2	F1238I	Neutral	0.246
NOTCH3	Q9UM47-1.2	F1238K	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	F1238L	Neutral	0.246
NOTCH3	Q9UM47-1.2	F1238M	Neutral	0.247
NOTCH3	Q9UM47-1.2	F1238N	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	F1238P	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	F1238Q	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	F1238R	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	F1238S	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	F1238T	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	F1238V	Pathogenic	0.581
NOTCH3	Q9UM47-1.2	F1238W	Neutral	0.063
NOTCH3	Q9UM47-1.2	F1238Y	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1239A	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1239C	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1239D	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1239E	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1239F	Neutral	0.011
NOTCH3	Q9UM47-1.2	S1239G	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1239H	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1239I	Neutral	0.012
NOTCH3	Q9UM47-1.2	S1239K	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1239L	Neutral	0.012
NOTCH3	Q9UM47-1.2	S1239M	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1239N	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1239P	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1239Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1239R	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1239T	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1239V	Neutral	0.013
NOTCH3	Q9UM47-1.2	S1239W	Neutral	0.045
NOTCH3	Q9UM47-1.2	S1239Y	Neutral	0.011
NOTCH3	Q9UM47-1.2	G1240A	Neutral	0.244
NOTCH3	Q9UM47-1.2	G1240C	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	G1240D	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	G1240E	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	G1240F	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1240H	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G1240I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1240K	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	G1240L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1240M	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G1240N	Neutral	0.224
NOTCH3	Q9UM47-1.2	G1240P	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	G1240Q	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G1240R	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	G1240S	Neutral	0.239
NOTCH3	Q9UM47-1.2	G1240T	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	G1240V	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G1240W	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G1240Y	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	P1241A	Neutral	0.027
NOTCH3	Q9UM47-1.2	P1241C	Neutral	0.385
NOTCH3	Q9UM47-1.2	P1241D	Neutral	0.03
NOTCH3	Q9UM47-1.2	P1241E	Neutral	0.028
NOTCH3	Q9UM47-1.2	P1241F	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	P1241G	Neutral	0.106
NOTCH3	Q9UM47-1.2	P1241H	Neutral	0.112
NOTCH3	Q9UM47-1.2	P1241I	Neutral	0.359
NOTCH3	Q9UM47-1.2	P1241K	Neutral	0.025
NOTCH3	Q9UM47-1.2	P1241L	Neutral	0.359
NOTCH3	Q9UM47-1.2	P1241M	Neutral	0.109
NOTCH3	Q9UM47-1.2	P1241N	Neutral	0.121
NOTCH3	Q9UM47-1.2	P1241Q	Neutral	0.027
NOTCH3	Q9UM47-1.2	P1241R	Neutral	0.102
NOTCH3	Q9UM47-1.2	P1241S	Neutral	0.028
NOTCH3	Q9UM47-1.2	P1241T	Neutral	0.029
NOTCH3	Q9UM47-1.2	P1241V	Neutral	0.117
NOTCH3	Q9UM47-1.2	P1241W	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	P1241Y	Neutral	0.343
NOTCH3	Q9UM47-1.2	R1242A	Neutral	0.464
NOTCH3	Q9UM47-1.2	R1242C	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	R1242D	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	R1242E	Neutral	0.181
NOTCH3	Q9UM47-1.2	R1242F	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	R1242G	Pathogenic	0.785
NOTCH3	Q9UM47-1.2	R1242H	Neutral	0.188
NOTCH3	Q9UM47-1.2	R1242I	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	R1242K	Neutral	0.012
NOTCH3	Q9UM47-1.2	R1242L	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	R1242M	Pathogenic	0.52
NOTCH3	Q9UM47-1.2	R1242N	Neutral	0.174
NOTCH3	Q9UM47-1.2	R1242P	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	R1242Q	Neutral	0.047
NOTCH3	Q9UM47-1.2	R1242S	Neutral	0.469
NOTCH3	Q9UM47-1.2	R1242T	Neutral	0.488
NOTCH3	Q9UM47-1.2	R1242V	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	R1242W	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	R1242Y	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	C1243A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C1243D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1243E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1243F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C1243G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1243H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1243I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1243K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1243L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1243M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C1243N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1243P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1243Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1243R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1243S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C1243T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C1243V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C1243W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C1243Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	Q1244A	Neutral	0.096
NOTCH3	Q9UM47-1.2	Q1244C	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	Q1244D	Neutral	0.025
NOTCH3	Q9UM47-1.2	Q1244E	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1244F	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	Q1244G	Neutral	0.309
NOTCH3	Q9UM47-1.2	Q1244H	Neutral	0.027
NOTCH3	Q9UM47-1.2	Q1244I	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	Q1244K	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q1244L	Neutral	0.36
NOTCH3	Q9UM47-1.2	Q1244M	Neutral	0.026
NOTCH3	Q9UM47-1.2	Q1244N	Neutral	0.025
NOTCH3	Q9UM47-1.2	Q1244P	Neutral	0.104
NOTCH3	Q9UM47-1.2	Q1244R	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q1244S	Neutral	0.023
NOTCH3	Q9UM47-1.2	Q1244T	Neutral	0.105
NOTCH3	Q9UM47-1.2	Q1244V	Neutral	0.36
NOTCH3	Q9UM47-1.2	Q1244W	Neutral	0.327
NOTCH3	Q9UM47-1.2	Q1244Y	Neutral	0.103
NOTCH3	Q9UM47-1.2	T1245A	Neutral	0.043
NOTCH3	Q9UM47-1.2	T1245C	Neutral	0.18
NOTCH3	Q9UM47-1.2	T1245D	Neutral	0.183
NOTCH3	Q9UM47-1.2	T1245E	Neutral	0.175
NOTCH3	Q9UM47-1.2	T1245F	Neutral	0.468
NOTCH3	Q9UM47-1.2	T1245G	Neutral	0.462
NOTCH3	Q9UM47-1.2	T1245H	Neutral	0.481
NOTCH3	Q9UM47-1.2	T1245I	Neutral	0.168
NOTCH3	Q9UM47-1.2	T1245K	Neutral	0.161
NOTCH3	Q9UM47-1.2	T1245L	Neutral	0.168
NOTCH3	Q9UM47-1.2	T1245M	Neutral	0.167
NOTCH3	Q9UM47-1.2	T1245N	Neutral	0.047
NOTCH3	Q9UM47-1.2	T1245P	Neutral	0.182
NOTCH3	Q9UM47-1.2	T1245Q	Neutral	0.172
NOTCH3	Q9UM47-1.2	T1245R	Neutral	0.155
NOTCH3	Q9UM47-1.2	T1245S	Neutral	0.01
NOTCH3	Q9UM47-1.2	T1245V	Neutral	0.045
NOTCH3	Q9UM47-1.2	T1245W	Neutral	0.442
NOTCH3	Q9UM47-1.2	T1245Y	Neutral	0.46
NOTCH3	Q9UM47-1.2	V1246A	Neutral	0.068
NOTCH3	Q9UM47-1.2	V1246C	Neutral	0.262
NOTCH3	Q9UM47-1.2	V1246D	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	V1246E	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	V1246F	Neutral	0.254
NOTCH3	Q9UM47-1.2	V1246G	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	V1246H	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	V1246I	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1246K	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	V1246L	Neutral	0.017
NOTCH3	Q9UM47-1.2	V1246M	Neutral	0.017
NOTCH3	Q9UM47-1.2	V1246N	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	V1246P	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	V1246Q	Pathogenic	0.629
NOTCH3	Q9UM47-1.2	V1246R	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	V1246S	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	V1246T	Neutral	0.074
NOTCH3	Q9UM47-1.2	V1246W	Pathogenic	0.864
NOTCH3	Q9UM47-1.2	V1246Y	Neutral	0.249
NOTCH3	Q9UM47-1.2	L1247A	Neutral	0.021
NOTCH3	Q9UM47-1.2	L1247C	Neutral	0.022
NOTCH3	Q9UM47-1.2	L1247D	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	L1247E	Neutral	0.343
NOTCH3	Q9UM47-1.2	L1247F	Neutral	0.005
NOTCH3	Q9UM47-1.2	L1247G	Pathogenic	0.651
NOTCH3	Q9UM47-1.2	L1247H	Neutral	0.349
NOTCH3	Q9UM47-1.2	L1247I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1247K	Neutral	0.104
NOTCH3	Q9UM47-1.2	L1247M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1247N	Neutral	0.331
NOTCH3	Q9UM47-1.2	L1247P	Neutral	0.324
NOTCH3	Q9UM47-1.2	L1247Q	Neutral	0.104
NOTCH3	Q9UM47-1.2	L1247R	Neutral	0.1
NOTCH3	Q9UM47-1.2	L1247S	Neutral	0.09
NOTCH3	Q9UM47-1.2	L1247T	Neutral	0.023
NOTCH3	Q9UM47-1.2	L1247V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1247W	Neutral	0.093
NOTCH3	Q9UM47-1.2	L1247Y	Neutral	0.024
NOTCH3	Q9UM47-1.2	S1248A	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1248C	Neutral	0.045
NOTCH3	Q9UM47-1.2	S1248D	Neutral	0.01
NOTCH3	Q9UM47-1.2	S1248E	Neutral	0.009
NOTCH3	Q9UM47-1.2	S1248F	Neutral	0.152
NOTCH3	Q9UM47-1.2	S1248G	Neutral	0.01
NOTCH3	Q9UM47-1.2	S1248H	Neutral	0.04
NOTCH3	Q9UM47-1.2	S1248I	Neutral	0.157
NOTCH3	Q9UM47-1.2	S1248K	Neutral	0.008
NOTCH3	Q9UM47-1.2	S1248L	Neutral	0.157
NOTCH3	Q9UM47-1.2	S1248M	Neutral	0.039
NOTCH3	Q9UM47-1.2	S1248N	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1248P	Neutral	0.044
NOTCH3	Q9UM47-1.2	S1248Q	Neutral	0.009
NOTCH3	Q9UM47-1.2	S1248R	Neutral	0.036
NOTCH3	Q9UM47-1.2	S1248T	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1248V	Neutral	0.166
NOTCH3	Q9UM47-1.2	S1248W	Neutral	0.423
NOTCH3	Q9UM47-1.2	S1248Y	Neutral	0.148
NOTCH3	Q9UM47-1.2	P1249A	Neutral	0.013
NOTCH3	Q9UM47-1.2	P1249C	Neutral	0.225
NOTCH3	Q9UM47-1.2	P1249D	Neutral	0.014
NOTCH3	Q9UM47-1.2	P1249E	Neutral	0.013
NOTCH3	Q9UM47-1.2	P1249F	Pathogenic	0.532
NOTCH3	Q9UM47-1.2	P1249G	Neutral	0.052
NOTCH3	Q9UM47-1.2	P1249H	Neutral	0.055
NOTCH3	Q9UM47-1.2	P1249I	Neutral	0.206
NOTCH3	Q9UM47-1.2	P1249K	Neutral	0.012
NOTCH3	Q9UM47-1.2	P1249L	Neutral	0.206
NOTCH3	Q9UM47-1.2	P1249M	Neutral	0.054
NOTCH3	Q9UM47-1.2	P1249N	Neutral	0.06
NOTCH3	Q9UM47-1.2	P1249Q	Neutral	0.013
NOTCH3	Q9UM47-1.2	P1249R	Neutral	0.05
NOTCH3	Q9UM47-1.2	P1249S	Neutral	0.013
NOTCH3	Q9UM47-1.2	P1249T	Neutral	0.014
NOTCH3	Q9UM47-1.2	P1249V	Neutral	0.058
NOTCH3	Q9UM47-1.2	P1249W	Pathogenic	0.506
NOTCH3	Q9UM47-1.2	P1249Y	Neutral	0.195
NOTCH3	Q9UM47-1.2	C1250A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C1250D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1250E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1250F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C1250G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1250H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1250I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1250K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1250L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1250M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C1250N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1250P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1250Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1250R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1250S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C1250T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C1250V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C1250W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C1250Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	E1251A	Neutral	0.04
NOTCH3	Q9UM47-1.2	E1251C	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	E1251D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1251F	Neutral	0.484
NOTCH3	Q9UM47-1.2	E1251G	Neutral	0.151
NOTCH3	Q9UM47-1.2	E1251H	Neutral	0.01
NOTCH3	Q9UM47-1.2	E1251I	Neutral	0.495
NOTCH3	Q9UM47-1.2	E1251K	Neutral	0.002
NOTCH3	Q9UM47-1.2	E1251L	Neutral	0.494
NOTCH3	Q9UM47-1.2	E1251M	Neutral	0.176
NOTCH3	Q9UM47-1.2	E1251N	Neutral	0.01
NOTCH3	Q9UM47-1.2	E1251P	Neutral	0.044
NOTCH3	Q9UM47-1.2	E1251Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1251R	Neutral	0.009
NOTCH3	Q9UM47-1.2	E1251S	Neutral	0.009
NOTCH3	Q9UM47-1.2	E1251T	Neutral	0.044
NOTCH3	Q9UM47-1.2	E1251V	Neutral	0.182
NOTCH3	Q9UM47-1.2	E1251W	Neutral	0.458
NOTCH3	Q9UM47-1.2	E1251Y	Neutral	0.167
NOTCH3	Q9UM47-1.2	S1252A	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1252C	Neutral	0.054
NOTCH3	Q9UM47-1.2	S1252D	Neutral	0.012
NOTCH3	Q9UM47-1.2	S1252E	Neutral	0.011
NOTCH3	Q9UM47-1.2	S1252F	Neutral	0.179
NOTCH3	Q9UM47-1.2	S1252G	Neutral	0.012
NOTCH3	Q9UM47-1.2	S1252H	Neutral	0.048
NOTCH3	Q9UM47-1.2	S1252I	Neutral	0.186
NOTCH3	Q9UM47-1.2	S1252K	Neutral	0.01
NOTCH3	Q9UM47-1.2	S1252L	Neutral	0.185
NOTCH3	Q9UM47-1.2	S1252M	Neutral	0.047
NOTCH3	Q9UM47-1.2	S1252N	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1252P	Neutral	0.054
NOTCH3	Q9UM47-1.2	S1252Q	Neutral	0.011
NOTCH3	Q9UM47-1.2	S1252R	Neutral	0.043
NOTCH3	Q9UM47-1.2	S1252T	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1252V	Neutral	0.196
NOTCH3	Q9UM47-1.2	S1252W	Neutral	0.473
NOTCH3	Q9UM47-1.2	S1252Y	Neutral	0.175
NOTCH3	Q9UM47-1.2	Q1253A	Neutral	0.048
NOTCH3	Q9UM47-1.2	Q1253C	Pathogenic	0.529
NOTCH3	Q9UM47-1.2	Q1253D	Neutral	0.012
NOTCH3	Q9UM47-1.2	Q1253E	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1253F	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	Q1253G	Neutral	0.175
NOTCH3	Q9UM47-1.2	Q1253H	Neutral	0.013
NOTCH3	Q9UM47-1.2	Q1253I	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	Q1253K	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q1253L	Neutral	0.21
NOTCH3	Q9UM47-1.2	Q1253M	Neutral	0.013
NOTCH3	Q9UM47-1.2	Q1253N	Neutral	0.012
NOTCH3	Q9UM47-1.2	Q1253P	Neutral	0.052
NOTCH3	Q9UM47-1.2	Q1253R	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q1253S	Neutral	0.011
NOTCH3	Q9UM47-1.2	Q1253T	Neutral	0.052
NOTCH3	Q9UM47-1.2	Q1253V	Neutral	0.21
NOTCH3	Q9UM47-1.2	Q1253W	Neutral	0.187
NOTCH3	Q9UM47-1.2	Q1253Y	Neutral	0.052
NOTCH3	Q9UM47-1.2	P1254A	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	P1254C	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	P1254D	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	P1254E	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	P1254F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P1254G	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	P1254H	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	P1254I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P1254K	Pathogenic	0.671
NOTCH3	Q9UM47-1.2	P1254L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P1254M	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	P1254N	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	P1254Q	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	P1254R	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	P1254S	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	P1254T	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	P1254V	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	P1254W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P1254Y	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	C1255A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C1255D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1255E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1255F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C1255G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1255H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1255I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1255K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1255L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1255M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C1255N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1255P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1255Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1255R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1255S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C1255T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C1255V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C1255W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C1255Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	Q1256A	Neutral	0.118
NOTCH3	Q9UM47-1.2	Q1256C	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	Q1256D	Neutral	0.031
NOTCH3	Q9UM47-1.2	Q1256E	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q1256F	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	Q1256G	Neutral	0.362
NOTCH3	Q9UM47-1.2	Q1256H	Neutral	0.034
NOTCH3	Q9UM47-1.2	Q1256I	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	Q1256K	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q1256L	Neutral	0.416
NOTCH3	Q9UM47-1.2	Q1256M	Neutral	0.033
NOTCH3	Q9UM47-1.2	Q1256N	Neutral	0.032
NOTCH3	Q9UM47-1.2	Q1256P	Neutral	0.128
NOTCH3	Q9UM47-1.2	Q1256R	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q1256S	Neutral	0.029
NOTCH3	Q9UM47-1.2	Q1256T	Neutral	0.129
NOTCH3	Q9UM47-1.2	Q1256V	Neutral	0.416
NOTCH3	Q9UM47-1.2	Q1256W	Neutral	0.381
NOTCH3	Q9UM47-1.2	Q1256Y	Neutral	0.127
NOTCH3	Q9UM47-1.2	H1257A	Neutral	0.472
NOTCH3	Q9UM47-1.2	H1257C	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	H1257D	Neutral	0.178
NOTCH3	Q9UM47-1.2	H1257E	Neutral	0.048
NOTCH3	Q9UM47-1.2	H1257F	Neutral	0.185
NOTCH3	Q9UM47-1.2	H1257G	Neutral	0.453
NOTCH3	Q9UM47-1.2	H1257I	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	H1257K	Neutral	0.184
NOTCH3	Q9UM47-1.2	H1257L	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	H1257M	Pathogenic	0.517
NOTCH3	Q9UM47-1.2	H1257N	Neutral	0.011
NOTCH3	Q9UM47-1.2	H1257P	Neutral	0.495
NOTCH3	Q9UM47-1.2	H1257Q	Neutral	0.049
NOTCH3	Q9UM47-1.2	H1257R	Neutral	0.045
NOTCH3	Q9UM47-1.2	H1257S	Neutral	0.167
NOTCH3	Q9UM47-1.2	H1257T	Neutral	0.497
NOTCH3	Q9UM47-1.2	H1257V	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	H1257W	Neutral	0.481
NOTCH3	Q9UM47-1.2	H1257Y	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1258A	Neutral	0.202
NOTCH3	Q9UM47-1.2	G1258C	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G1258D	Pathogenic	0.514
NOTCH3	Q9UM47-1.2	G1258E	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	G1258F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	G1258H	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	G1258I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G1258K	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	G1258L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G1258M	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	G1258N	Neutral	0.185
NOTCH3	Q9UM47-1.2	G1258P	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	G1258Q	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	G1258R	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	G1258S	Neutral	0.198
NOTCH3	Q9UM47-1.2	G1258T	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	G1258V	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G1258W	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	G1258Y	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	G1259A	Neutral	0.235
NOTCH3	Q9UM47-1.2	G1259C	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G1259D	Pathogenic	0.561
NOTCH3	Q9UM47-1.2	G1259E	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	G1259F	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G1259H	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	G1259I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1259K	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	G1259L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1259M	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1259N	Neutral	0.216
NOTCH3	Q9UM47-1.2	G1259P	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	G1259Q	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	G1259R	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G1259S	Neutral	0.23
NOTCH3	Q9UM47-1.2	G1259T	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	G1259V	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	G1259W	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	G1259Y	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	Q1260A	Neutral	0.033
NOTCH3	Q9UM47-1.2	Q1260C	Neutral	0.436
NOTCH3	Q9UM47-1.2	Q1260D	Neutral	0.008
NOTCH3	Q9UM47-1.2	Q1260E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1260F	Neutral	0.444
NOTCH3	Q9UM47-1.2	Q1260G	Neutral	0.127
NOTCH3	Q9UM47-1.2	Q1260H	Neutral	0.009
NOTCH3	Q9UM47-1.2	Q1260I	Neutral	0.454
NOTCH3	Q9UM47-1.2	Q1260K	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q1260L	Neutral	0.155
NOTCH3	Q9UM47-1.2	Q1260M	Neutral	0.009
NOTCH3	Q9UM47-1.2	Q1260N	Neutral	0.008
NOTCH3	Q9UM47-1.2	Q1260P	Neutral	0.036
NOTCH3	Q9UM47-1.2	Q1260R	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q1260S	Neutral	0.008
NOTCH3	Q9UM47-1.2	Q1260T	Neutral	0.037
NOTCH3	Q9UM47-1.2	Q1260V	Neutral	0.154
NOTCH3	Q9UM47-1.2	Q1260W	Neutral	0.136
NOTCH3	Q9UM47-1.2	Q1260Y	Neutral	0.036
NOTCH3	Q9UM47-1.2	C1261A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C1261D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1261E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1261F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C1261G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1261H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1261I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1261K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1261L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1261M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C1261N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1261P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1261Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1261R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1261S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C1261T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C1261V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C1261W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C1261Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	R1262A	Neutral	0.031
NOTCH3	Q9UM47-1.2	R1262C	Neutral	0.417
NOTCH3	Q9UM47-1.2	R1262D	Neutral	0.136
NOTCH3	Q9UM47-1.2	R1262E	Neutral	0.008
NOTCH3	Q9UM47-1.2	R1262F	Neutral	0.465
NOTCH3	Q9UM47-1.2	R1262G	Neutral	0.119
NOTCH3	Q9UM47-1.2	R1262H	Neutral	0.008
NOTCH3	Q9UM47-1.2	R1262I	Neutral	0.455
NOTCH3	Q9UM47-1.2	R1262K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R1262L	Neutral	0.155
NOTCH3	Q9UM47-1.2	R1262M	Neutral	0.039
NOTCH3	Q9UM47-1.2	R1262N	Neutral	0.008
NOTCH3	Q9UM47-1.2	R1262P	Neutral	0.137
NOTCH3	Q9UM47-1.2	R1262Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1262S	Neutral	0.032
NOTCH3	Q9UM47-1.2	R1262T	Neutral	0.034
NOTCH3	Q9UM47-1.2	R1262V	Neutral	0.436
NOTCH3	Q9UM47-1.2	R1262W	Neutral	0.464
NOTCH3	Q9UM47-1.2	R1262Y	Neutral	0.163
NOTCH3	Q9UM47-1.2	P1263A	Neutral	0.047
NOTCH3	Q9UM47-1.2	P1263C	Pathogenic	0.524
NOTCH3	Q9UM47-1.2	P1263D	Neutral	0.051
NOTCH3	Q9UM47-1.2	P1263E	Neutral	0.048
NOTCH3	Q9UM47-1.2	P1263F	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	P1263G	Neutral	0.173
NOTCH3	Q9UM47-1.2	P1263H	Neutral	0.181
NOTCH3	Q9UM47-1.2	P1263I	Neutral	0.497
NOTCH3	Q9UM47-1.2	P1263K	Neutral	0.044
NOTCH3	Q9UM47-1.2	P1263L	Neutral	0.496
NOTCH3	Q9UM47-1.2	P1263M	Neutral	0.177
NOTCH3	Q9UM47-1.2	P1263N	Neutral	0.195
NOTCH3	Q9UM47-1.2	P1263Q	Neutral	0.047
NOTCH3	Q9UM47-1.2	P1263R	Neutral	0.166
NOTCH3	Q9UM47-1.2	P1263S	Neutral	0.048
NOTCH3	Q9UM47-1.2	P1263T	Neutral	0.051
NOTCH3	Q9UM47-1.2	P1263V	Neutral	0.188
NOTCH3	Q9UM47-1.2	P1263W	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	P1263Y	Neutral	0.478
NOTCH3	Q9UM47-1.2	S1264A	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1264C	Neutral	0.04
NOTCH3	Q9UM47-1.2	S1264D	Neutral	0.009
NOTCH3	Q9UM47-1.2	S1264E	Neutral	0.008
NOTCH3	Q9UM47-1.2	S1264F	Neutral	0.138
NOTCH3	Q9UM47-1.2	S1264G	Neutral	0.009
NOTCH3	Q9UM47-1.2	S1264H	Neutral	0.036
NOTCH3	Q9UM47-1.2	S1264I	Neutral	0.143
NOTCH3	Q9UM47-1.2	S1264K	Neutral	0.008
NOTCH3	Q9UM47-1.2	S1264L	Neutral	0.143
NOTCH3	Q9UM47-1.2	S1264M	Neutral	0.035
NOTCH3	Q9UM47-1.2	S1264N	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1264P	Neutral	0.04
NOTCH3	Q9UM47-1.2	S1264Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	S1264R	Neutral	0.032
NOTCH3	Q9UM47-1.2	S1264T	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1264V	Neutral	0.152
NOTCH3	Q9UM47-1.2	S1264W	Neutral	0.396
NOTCH3	Q9UM47-1.2	S1264Y	Neutral	0.134
NOTCH3	Q9UM47-1.2	P1265A	Neutral	0.012
NOTCH3	Q9UM47-1.2	P1265C	Neutral	0.22
NOTCH3	Q9UM47-1.2	P1265D	Neutral	0.014
NOTCH3	Q9UM47-1.2	P1265E	Neutral	0.013
NOTCH3	Q9UM47-1.2	P1265F	Pathogenic	0.524
NOTCH3	Q9UM47-1.2	P1265G	Neutral	0.051
NOTCH3	Q9UM47-1.2	P1265H	Neutral	0.054
NOTCH3	Q9UM47-1.2	P1265I	Neutral	0.202
NOTCH3	Q9UM47-1.2	P1265K	Neutral	0.012
NOTCH3	Q9UM47-1.2	P1265L	Neutral	0.202
NOTCH3	Q9UM47-1.2	P1265M	Neutral	0.052
NOTCH3	Q9UM47-1.2	P1265N	Neutral	0.058
NOTCH3	Q9UM47-1.2	P1265Q	Neutral	0.012
NOTCH3	Q9UM47-1.2	P1265R	Neutral	0.048
NOTCH3	Q9UM47-1.2	P1265S	Neutral	0.013
NOTCH3	Q9UM47-1.2	P1265T	Neutral	0.013
NOTCH3	Q9UM47-1.2	P1265V	Neutral	0.056
NOTCH3	Q9UM47-1.2	P1265W	Neutral	0.498
NOTCH3	Q9UM47-1.2	P1265Y	Neutral	0.19
NOTCH3	Q9UM47-1.2	G1266A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1266C	Neutral	0.179
NOTCH3	Q9UM47-1.2	G1266D	Neutral	0.01
NOTCH3	Q9UM47-1.2	G1266E	Neutral	0.042
NOTCH3	Q9UM47-1.2	G1266F	Neutral	0.154
NOTCH3	Q9UM47-1.2	G1266H	Neutral	0.04
NOTCH3	Q9UM47-1.2	G1266I	Neutral	0.464
NOTCH3	Q9UM47-1.2	G1266K	Neutral	0.038
NOTCH3	Q9UM47-1.2	G1266L	Neutral	0.464
NOTCH3	Q9UM47-1.2	G1266M	Neutral	0.159
NOTCH3	Q9UM47-1.2	G1266N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1266P	Neutral	0.045
NOTCH3	Q9UM47-1.2	G1266Q	Neutral	0.041
NOTCH3	Q9UM47-1.2	G1266R	Neutral	0.036
NOTCH3	Q9UM47-1.2	G1266S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1266T	Neutral	0.044
NOTCH3	Q9UM47-1.2	G1266V	Neutral	0.169
NOTCH3	Q9UM47-1.2	G1266W	Neutral	0.035
NOTCH3	Q9UM47-1.2	G1266Y	Neutral	0.15
NOTCH3	Q9UM47-1.2	P1267A	Neutral	0.009
NOTCH3	Q9UM47-1.2	P1267C	Neutral	0.162
NOTCH3	Q9UM47-1.2	P1267D	Neutral	0.009
NOTCH3	Q9UM47-1.2	P1267E	Neutral	0.009
NOTCH3	Q9UM47-1.2	P1267F	Neutral	0.43
NOTCH3	Q9UM47-1.2	P1267G	Neutral	0.035
NOTCH3	Q9UM47-1.2	P1267H	Neutral	0.037
NOTCH3	Q9UM47-1.2	P1267I	Neutral	0.147
NOTCH3	Q9UM47-1.2	P1267K	Neutral	0.008
NOTCH3	Q9UM47-1.2	P1267L	Neutral	0.147
NOTCH3	Q9UM47-1.2	P1267M	Neutral	0.036
NOTCH3	Q9UM47-1.2	P1267N	Neutral	0.041
NOTCH3	Q9UM47-1.2	P1267Q	Neutral	0.009
NOTCH3	Q9UM47-1.2	P1267R	Neutral	0.034
NOTCH3	Q9UM47-1.2	P1267S	Neutral	0.009
NOTCH3	Q9UM47-1.2	P1267T	Neutral	0.009
NOTCH3	Q9UM47-1.2	P1267V	Neutral	0.039
NOTCH3	Q9UM47-1.2	P1267W	Neutral	0.405
NOTCH3	Q9UM47-1.2	P1267Y	Neutral	0.138
NOTCH3	Q9UM47-1.2	G1268A	Neutral	0.003
NOTCH3	Q9UM47-1.2	G1268C	Neutral	0.182
NOTCH3	Q9UM47-1.2	G1268D	Neutral	0.01
NOTCH3	Q9UM47-1.2	G1268E	Neutral	0.043
NOTCH3	Q9UM47-1.2	G1268F	Neutral	0.157
NOTCH3	Q9UM47-1.2	G1268H	Neutral	0.041
NOTCH3	Q9UM47-1.2	G1268I	Neutral	0.469
NOTCH3	Q9UM47-1.2	G1268K	Neutral	0.039
NOTCH3	Q9UM47-1.2	G1268L	Neutral	0.469
NOTCH3	Q9UM47-1.2	G1268M	Neutral	0.162
NOTCH3	Q9UM47-1.2	G1268N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1268P	Neutral	0.046
NOTCH3	Q9UM47-1.2	G1268Q	Neutral	0.042
NOTCH3	Q9UM47-1.2	G1268R	Neutral	0.037
NOTCH3	Q9UM47-1.2	G1268S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1268T	Neutral	0.045
NOTCH3	Q9UM47-1.2	G1268V	Neutral	0.172
NOTCH3	Q9UM47-1.2	G1268W	Neutral	0.035
NOTCH3	Q9UM47-1.2	G1268Y	Neutral	0.153
NOTCH3	Q9UM47-1.2	G1269A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1269C	Neutral	0.124
NOTCH3	Q9UM47-1.2	G1269D	Neutral	0.007
NOTCH3	Q9UM47-1.2	G1269E	Neutral	0.028
NOTCH3	Q9UM47-1.2	G1269F	Neutral	0.106
NOTCH3	Q9UM47-1.2	G1269H	Neutral	0.027
NOTCH3	Q9UM47-1.2	G1269I	Neutral	0.36
NOTCH3	Q9UM47-1.2	G1269K	Neutral	0.025
NOTCH3	Q9UM47-1.2	G1269L	Neutral	0.36
NOTCH3	Q9UM47-1.2	G1269M	Neutral	0.109
NOTCH3	Q9UM47-1.2	G1269N	Neutral	0.001
NOTCH3	Q9UM47-1.2	G1269P	Neutral	0.03
NOTCH3	Q9UM47-1.2	G1269Q	Neutral	0.027
NOTCH3	Q9UM47-1.2	G1269R	Neutral	0.024
NOTCH3	Q9UM47-1.2	G1269S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1269T	Neutral	0.029
NOTCH3	Q9UM47-1.2	G1269V	Neutral	0.117
NOTCH3	Q9UM47-1.2	G1269W	Neutral	0.023
NOTCH3	Q9UM47-1.2	G1269Y	Neutral	0.103
NOTCH3	Q9UM47-1.2	G1270A	Neutral	0.001
NOTCH3	Q9UM47-1.2	G1270C	Neutral	0.097
NOTCH3	Q9UM47-1.2	G1270D	Neutral	0.005
NOTCH3	Q9UM47-1.2	G1270E	Neutral	0.021
NOTCH3	Q9UM47-1.2	G1270F	Neutral	0.082
NOTCH3	Q9UM47-1.2	G1270H	Neutral	0.02
NOTCH3	Q9UM47-1.2	G1270I	Neutral	0.299
NOTCH3	Q9UM47-1.2	G1270K	Neutral	0.019
NOTCH3	Q9UM47-1.2	G1270L	Neutral	0.299
NOTCH3	Q9UM47-1.2	G1270M	Neutral	0.085
NOTCH3	Q9UM47-1.2	G1270N	Neutral	0.001
NOTCH3	Q9UM47-1.2	G1270P	Neutral	0.023
NOTCH3	Q9UM47-1.2	G1270Q	Neutral	0.021
NOTCH3	Q9UM47-1.2	G1270R	Neutral	0.018
NOTCH3	Q9UM47-1.2	G1270S	Neutral	0.001
NOTCH3	Q9UM47-1.2	G1270T	Neutral	0.022
NOTCH3	Q9UM47-1.2	G1270V	Neutral	0.091
NOTCH3	Q9UM47-1.2	G1270W	Neutral	0.017
NOTCH3	Q9UM47-1.2	G1270Y	Neutral	0.08
NOTCH3	Q9UM47-1.2	L1271A	Neutral	0.015
NOTCH3	Q9UM47-1.2	L1271C	Neutral	0.016
NOTCH3	Q9UM47-1.2	L1271D	Pathogenic	0.615
NOTCH3	Q9UM47-1.2	L1271E	Neutral	0.273
NOTCH3	Q9UM47-1.2	L1271F	Neutral	0.004
NOTCH3	Q9UM47-1.2	L1271G	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	L1271H	Neutral	0.278
NOTCH3	Q9UM47-1.2	L1271I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1271K	Neutral	0.077
NOTCH3	Q9UM47-1.2	L1271M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1271N	Neutral	0.263
NOTCH3	Q9UM47-1.2	L1271P	Neutral	0.256
NOTCH3	Q9UM47-1.2	L1271Q	Neutral	0.077
NOTCH3	Q9UM47-1.2	L1271R	Neutral	0.074
NOTCH3	Q9UM47-1.2	L1271S	Neutral	0.067
NOTCH3	Q9UM47-1.2	L1271T	Neutral	0.017
NOTCH3	Q9UM47-1.2	L1271V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1271W	Neutral	0.069
NOTCH3	Q9UM47-1.2	L1271Y	Neutral	0.017
NOTCH3	Q9UM47-1.2	T1272A	Neutral	0.015
NOTCH3	Q9UM47-1.2	T1272C	Neutral	0.069
NOTCH3	Q9UM47-1.2	T1272D	Neutral	0.07
NOTCH3	Q9UM47-1.2	T1272E	Neutral	0.067
NOTCH3	Q9UM47-1.2	T1272F	Neutral	0.228
NOTCH3	Q9UM47-1.2	T1272G	Neutral	0.224
NOTCH3	Q9UM47-1.2	T1272H	Neutral	0.238
NOTCH3	Q9UM47-1.2	T1272I	Neutral	0.063
NOTCH3	Q9UM47-1.2	T1272K	Neutral	0.061
NOTCH3	Q9UM47-1.2	T1272L	Neutral	0.063
NOTCH3	Q9UM47-1.2	T1272M	Neutral	0.063
NOTCH3	Q9UM47-1.2	T1272N	Neutral	0.016
NOTCH3	Q9UM47-1.2	T1272P	Neutral	0.07
NOTCH3	Q9UM47-1.2	T1272Q	Neutral	0.065
NOTCH3	Q9UM47-1.2	T1272R	Neutral	0.058
NOTCH3	Q9UM47-1.2	T1272S	Neutral	0.003
NOTCH3	Q9UM47-1.2	T1272V	Neutral	0.016
NOTCH3	Q9UM47-1.2	T1272W	Neutral	0.21
NOTCH3	Q9UM47-1.2	T1272Y	Neutral	0.223
NOTCH3	Q9UM47-1.2	F1273A	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	F1273C	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	F1273D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	F1273E	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	F1273G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	F1273H	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	F1273I	Pathogenic	0.513
NOTCH3	Q9UM47-1.2	F1273K	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	F1273L	Pathogenic	0.513
NOTCH3	Q9UM47-1.2	F1273M	Pathogenic	0.514
NOTCH3	Q9UM47-1.2	F1273N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	F1273P	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	F1273Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	F1273R	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	F1273S	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	F1273T	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	F1273V	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	F1273W	Neutral	0.178
NOTCH3	Q9UM47-1.2	F1273Y	Neutral	0.011
NOTCH3	Q9UM47-1.2	T1274A	Neutral	0.01
NOTCH3	Q9UM47-1.2	T1274C	Neutral	0.05
NOTCH3	Q9UM47-1.2	T1274D	Neutral	0.051
NOTCH3	Q9UM47-1.2	T1274E	Neutral	0.048
NOTCH3	Q9UM47-1.2	T1274F	Neutral	0.173
NOTCH3	Q9UM47-1.2	T1274G	Neutral	0.17
NOTCH3	Q9UM47-1.2	T1274H	Neutral	0.181
NOTCH3	Q9UM47-1.2	T1274I	Neutral	0.046
NOTCH3	Q9UM47-1.2	T1274K	Neutral	0.044
NOTCH3	Q9UM47-1.2	T1274L	Neutral	0.046
NOTCH3	Q9UM47-1.2	T1274M	Neutral	0.046
NOTCH3	Q9UM47-1.2	T1274N	Neutral	0.012
NOTCH3	Q9UM47-1.2	T1274P	Neutral	0.05
NOTCH3	Q9UM47-1.2	T1274Q	Neutral	0.047
NOTCH3	Q9UM47-1.2	T1274R	Neutral	0.042
NOTCH3	Q9UM47-1.2	T1274S	Neutral	0.002
NOTCH3	Q9UM47-1.2	T1274V	Neutral	0.011
NOTCH3	Q9UM47-1.2	T1274W	Neutral	0.159
NOTCH3	Q9UM47-1.2	T1274Y	Neutral	0.169
NOTCH3	Q9UM47-1.2	C1275A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C1275D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1275E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1275F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C1275G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1275H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1275I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1275K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1275L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1275M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C1275N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1275P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1275Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1275R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1275S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C1275T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C1275V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C1275W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C1275Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	H1276A	Neutral	0.19
NOTCH3	Q9UM47-1.2	H1276C	Pathogenic	0.537
NOTCH3	Q9UM47-1.2	H1276D	Neutral	0.054
NOTCH3	Q9UM47-1.2	H1276E	Neutral	0.013
NOTCH3	Q9UM47-1.2	H1276F	Neutral	0.056
NOTCH3	Q9UM47-1.2	H1276G	Neutral	0.179
NOTCH3	Q9UM47-1.2	H1276I	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	H1276K	Neutral	0.056
NOTCH3	Q9UM47-1.2	H1276L	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	H1276M	Neutral	0.22
NOTCH3	Q9UM47-1.2	H1276N	Neutral	0.003
NOTCH3	Q9UM47-1.2	H1276P	Neutral	0.205
NOTCH3	Q9UM47-1.2	H1276Q	Neutral	0.013
NOTCH3	Q9UM47-1.2	H1276R	Neutral	0.012
NOTCH3	Q9UM47-1.2	H1276S	Neutral	0.05
NOTCH3	Q9UM47-1.2	H1276T	Neutral	0.206
NOTCH3	Q9UM47-1.2	H1276V	Pathogenic	0.555
NOTCH3	Q9UM47-1.2	H1276W	Neutral	0.197
NOTCH3	Q9UM47-1.2	H1276Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	C1277A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C1277D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1277E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1277F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C1277G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1277H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1277I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1277K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1277L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1277M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C1277N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1277P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1277Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1277R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1277S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C1277T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C1277V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C1277W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C1277Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	A1278C	Neutral	0.0
NOTCH3	Q9UM47-1.2	A1278D	Neutral	0.008
NOTCH3	Q9UM47-1.2	A1278E	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1278F	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1278G	Neutral	0.0
NOTCH3	Q9UM47-1.2	A1278H	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1278I	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1278K	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1278L	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1278M	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1278N	Neutral	0.008
NOTCH3	Q9UM47-1.2	A1278P	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1278Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1278R	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1278S	Neutral	0.0
NOTCH3	Q9UM47-1.2	A1278T	Neutral	0.0
NOTCH3	Q9UM47-1.2	A1278V	Neutral	0.0
NOTCH3	Q9UM47-1.2	A1278W	Neutral	0.027
NOTCH3	Q9UM47-1.2	A1278Y	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q1279A	Neutral	0.009
NOTCH3	Q9UM47-1.2	Q1279C	Neutral	0.176
NOTCH3	Q9UM47-1.2	Q1279D	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q1279E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1279F	Neutral	0.181
NOTCH3	Q9UM47-1.2	Q1279G	Neutral	0.039
NOTCH3	Q9UM47-1.2	Q1279H	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q1279I	Neutral	0.187
NOTCH3	Q9UM47-1.2	Q1279K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1279L	Neutral	0.048
NOTCH3	Q9UM47-1.2	Q1279M	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q1279N	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q1279P	Neutral	0.01
NOTCH3	Q9UM47-1.2	Q1279R	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1279S	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q1279T	Neutral	0.01
NOTCH3	Q9UM47-1.2	Q1279V	Neutral	0.048
NOTCH3	Q9UM47-1.2	Q1279W	Neutral	0.042
NOTCH3	Q9UM47-1.2	Q1279Y	Neutral	0.01
NOTCH3	Q9UM47-1.2	P1280A	Neutral	0.025
NOTCH3	Q9UM47-1.2	P1280C	Neutral	0.364
NOTCH3	Q9UM47-1.2	P1280D	Neutral	0.027
NOTCH3	Q9UM47-1.2	P1280E	Neutral	0.026
NOTCH3	Q9UM47-1.2	P1280F	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	P1280G	Neutral	0.098
NOTCH3	Q9UM47-1.2	P1280H	Neutral	0.103
NOTCH3	Q9UM47-1.2	P1280I	Neutral	0.339
NOTCH3	Q9UM47-1.2	P1280K	Neutral	0.023
NOTCH3	Q9UM47-1.2	P1280L	Neutral	0.339
NOTCH3	Q9UM47-1.2	P1280M	Neutral	0.101
NOTCH3	Q9UM47-1.2	P1280N	Neutral	0.112
NOTCH3	Q9UM47-1.2	P1280Q	Neutral	0.025
NOTCH3	Q9UM47-1.2	P1280R	Neutral	0.094
NOTCH3	Q9UM47-1.2	P1280S	Neutral	0.026
NOTCH3	Q9UM47-1.2	P1280T	Neutral	0.027
NOTCH3	Q9UM47-1.2	P1280V	Neutral	0.108
NOTCH3	Q9UM47-1.2	P1280W	Pathogenic	0.669
NOTCH3	Q9UM47-1.2	P1280Y	Neutral	0.323
NOTCH3	Q9UM47-1.2	F1281A	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	F1281C	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	F1281D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	F1281E	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	F1281G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	F1281H	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	F1281I	Pathogenic	0.542
NOTCH3	Q9UM47-1.2	F1281K	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	F1281L	Pathogenic	0.543
NOTCH3	Q9UM47-1.2	F1281M	Pathogenic	0.544
NOTCH3	Q9UM47-1.2	F1281N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	F1281P	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	F1281Q	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	F1281R	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	F1281S	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	F1281T	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	F1281V	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	F1281W	Neutral	0.197
NOTCH3	Q9UM47-1.2	F1281Y	Neutral	0.013
NOTCH3	Q9UM47-1.2	W1282A	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	W1282C	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	W1282D	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	W1282E	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	W1282F	Neutral	0.017
NOTCH3	Q9UM47-1.2	W1282G	Pathogenic	0.536
NOTCH3	Q9UM47-1.2	W1282H	Pathogenic	0.602
NOTCH3	Q9UM47-1.2	W1282I	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	W1282K	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	W1282L	Pathogenic	0.604
NOTCH3	Q9UM47-1.2	W1282M	Neutral	0.252
NOTCH3	Q9UM47-1.2	W1282N	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	W1282P	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	W1282Q	Pathogenic	0.599
NOTCH3	Q9UM47-1.2	W1282R	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	W1282S	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	W1282T	Pathogenic	0.578
NOTCH3	Q9UM47-1.2	W1282V	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	W1282Y	Neutral	0.004
NOTCH3	Q9UM47-1.2	G1283A	Neutral	0.223
NOTCH3	Q9UM47-1.2	G1283C	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	G1283D	Pathogenic	0.545
NOTCH3	Q9UM47-1.2	G1283E	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G1283F	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G1283H	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	G1283I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1283K	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	G1283L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1283M	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G1283N	Neutral	0.205
NOTCH3	Q9UM47-1.2	G1283P	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	G1283Q	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	G1283R	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	G1283S	Neutral	0.219
NOTCH3	Q9UM47-1.2	G1283T	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	G1283V	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1283W	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	G1283Y	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	P1284A	Neutral	0.011
NOTCH3	Q9UM47-1.2	P1284C	Neutral	0.204
NOTCH3	Q9UM47-1.2	P1284D	Neutral	0.012
NOTCH3	Q9UM47-1.2	P1284E	Neutral	0.012
NOTCH3	Q9UM47-1.2	P1284F	Pathogenic	0.501
NOTCH3	Q9UM47-1.2	P1284G	Neutral	0.047
NOTCH3	Q9UM47-1.2	P1284H	Neutral	0.049
NOTCH3	Q9UM47-1.2	P1284I	Neutral	0.187
NOTCH3	Q9UM47-1.2	P1284K	Neutral	0.011
NOTCH3	Q9UM47-1.2	P1284L	Neutral	0.187
NOTCH3	Q9UM47-1.2	P1284M	Neutral	0.048
NOTCH3	Q9UM47-1.2	P1284N	Neutral	0.053
NOTCH3	Q9UM47-1.2	P1284Q	Neutral	0.011
NOTCH3	Q9UM47-1.2	P1284R	Neutral	0.044
NOTCH3	Q9UM47-1.2	P1284S	Neutral	0.012
NOTCH3	Q9UM47-1.2	P1284T	Neutral	0.012
NOTCH3	Q9UM47-1.2	P1284V	Neutral	0.051
NOTCH3	Q9UM47-1.2	P1284W	Neutral	0.475
NOTCH3	Q9UM47-1.2	P1284Y	Neutral	0.176
NOTCH3	Q9UM47-1.2	R1285A	Neutral	0.092
NOTCH3	Q9UM47-1.2	R1285C	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	R1285D	Neutral	0.334
NOTCH3	Q9UM47-1.2	R1285E	Neutral	0.025
NOTCH3	Q9UM47-1.2	R1285F	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	R1285G	Neutral	0.3
NOTCH3	Q9UM47-1.2	R1285H	Neutral	0.026
NOTCH3	Q9UM47-1.2	R1285I	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	R1285K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1285L	Neutral	0.368
NOTCH3	Q9UM47-1.2	R1285M	Neutral	0.113
NOTCH3	Q9UM47-1.2	R1285N	Neutral	0.024
NOTCH3	Q9UM47-1.2	R1285P	Neutral	0.336
NOTCH3	Q9UM47-1.2	R1285Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	R1285S	Neutral	0.094
NOTCH3	Q9UM47-1.2	R1285T	Neutral	0.101
NOTCH3	Q9UM47-1.2	R1285V	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	R1285W	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	R1285Y	Neutral	0.382
NOTCH3	Q9UM47-1.2	C1286A	Neutral	0.454
NOTCH3	Q9UM47-1.2	C1286D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1286E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1286F	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	C1286G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1286H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1286I	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	C1286K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1286L	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	C1286M	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	C1286N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1286P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1286Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1286R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C1286S	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	C1286T	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	C1286V	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C1286W	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	C1286Y	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	E1287A	Neutral	0.416
NOTCH3	Q9UM47-1.2	E1287C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	E1287D	Neutral	0.008
NOTCH3	Q9UM47-1.2	E1287F	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	E1287G	Pathogenic	0.75
NOTCH3	Q9UM47-1.2	E1287H	Neutral	0.151
NOTCH3	Q9UM47-1.2	E1287I	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	E1287K	Neutral	0.035
NOTCH3	Q9UM47-1.2	E1287L	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	E1287M	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	E1287N	Neutral	0.148
NOTCH3	Q9UM47-1.2	E1287P	Neutral	0.439
NOTCH3	Q9UM47-1.2	E1287Q	Neutral	0.009
NOTCH3	Q9UM47-1.2	E1287R	Neutral	0.136
NOTCH3	Q9UM47-1.2	E1287S	Neutral	0.138
NOTCH3	Q9UM47-1.2	E1287T	Neutral	0.44
NOTCH3	Q9UM47-1.2	E1287V	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	E1287W	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	E1287Y	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	R1288A	Neutral	0.034
NOTCH3	Q9UM47-1.2	R1288C	Neutral	0.438
NOTCH3	Q9UM47-1.2	R1288D	Neutral	0.147
NOTCH3	Q9UM47-1.2	R1288E	Neutral	0.009
NOTCH3	Q9UM47-1.2	R1288F	Neutral	0.487
NOTCH3	Q9UM47-1.2	R1288G	Neutral	0.128
NOTCH3	Q9UM47-1.2	R1288H	Neutral	0.009
NOTCH3	Q9UM47-1.2	R1288I	Neutral	0.476
NOTCH3	Q9UM47-1.2	R1288K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R1288L	Neutral	0.166
NOTCH3	Q9UM47-1.2	R1288M	Neutral	0.042
NOTCH3	Q9UM47-1.2	R1288N	Neutral	0.008
NOTCH3	Q9UM47-1.2	R1288P	Neutral	0.148
NOTCH3	Q9UM47-1.2	R1288Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1288S	Neutral	0.034
NOTCH3	Q9UM47-1.2	R1288T	Neutral	0.037
NOTCH3	Q9UM47-1.2	R1288V	Neutral	0.457
NOTCH3	Q9UM47-1.2	R1288W	Neutral	0.486
NOTCH3	Q9UM47-1.2	R1288Y	Neutral	0.175
NOTCH3	Q9UM47-1.2	V1289A	Neutral	0.004
NOTCH3	Q9UM47-1.2	V1289C	Neutral	0.019
NOTCH3	Q9UM47-1.2	V1289D	Neutral	0.291
NOTCH3	Q9UM47-1.2	V1289E	Neutral	0.086
NOTCH3	Q9UM47-1.2	V1289F	Neutral	0.018
NOTCH3	Q9UM47-1.2	V1289G	Neutral	0.257
NOTCH3	Q9UM47-1.2	V1289H	Neutral	0.29
NOTCH3	Q9UM47-1.2	V1289I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V1289K	Neutral	0.078
NOTCH3	Q9UM47-1.2	V1289L	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1289M	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1289N	Neutral	0.295
NOTCH3	Q9UM47-1.2	V1289P	Neutral	0.081
NOTCH3	Q9UM47-1.2	V1289Q	Neutral	0.084
NOTCH3	Q9UM47-1.2	V1289R	Neutral	0.269
NOTCH3	Q9UM47-1.2	V1289S	Neutral	0.077
NOTCH3	Q9UM47-1.2	V1289T	Neutral	0.004
NOTCH3	Q9UM47-1.2	V1289W	Neutral	0.256
NOTCH3	Q9UM47-1.2	V1289Y	Neutral	0.018
NOTCH3	Q9UM47-1.2	A1290C	Neutral	0.014
NOTCH3	Q9UM47-1.2	A1290D	Neutral	0.225
NOTCH3	Q9UM47-1.2	A1290E	Neutral	0.056
NOTCH3	Q9UM47-1.2	A1290F	Neutral	0.197
NOTCH3	Q9UM47-1.2	A1290G	Neutral	0.014
NOTCH3	Q9UM47-1.2	A1290H	Neutral	0.206
NOTCH3	Q9UM47-1.2	A1290I	Neutral	0.053
NOTCH3	Q9UM47-1.2	A1290K	Neutral	0.051
NOTCH3	Q9UM47-1.2	A1290L	Neutral	0.053
NOTCH3	Q9UM47-1.2	A1290M	Neutral	0.053
NOTCH3	Q9UM47-1.2	A1290N	Neutral	0.221
NOTCH3	Q9UM47-1.2	A1290P	Neutral	0.06
NOTCH3	Q9UM47-1.2	A1290Q	Neutral	0.055
NOTCH3	Q9UM47-1.2	A1290R	Neutral	0.049
NOTCH3	Q9UM47-1.2	A1290S	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1290T	Neutral	0.014
NOTCH3	Q9UM47-1.2	A1290V	Neutral	0.013
NOTCH3	Q9UM47-1.2	A1290W	Pathogenic	0.502
NOTCH3	Q9UM47-1.2	A1290Y	Neutral	0.193
NOTCH3	Q9UM47-1.2	R1291A	Neutral	0.128
NOTCH3	Q9UM47-1.2	R1291C	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	R1291D	Neutral	0.422
NOTCH3	Q9UM47-1.2	R1291E	Neutral	0.036
NOTCH3	Q9UM47-1.2	R1291F	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	R1291G	Neutral	0.384
NOTCH3	Q9UM47-1.2	R1291H	Neutral	0.038
NOTCH3	Q9UM47-1.2	R1291I	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	R1291K	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1291L	Neutral	0.458
NOTCH3	Q9UM47-1.2	R1291M	Neutral	0.156
NOTCH3	Q9UM47-1.2	R1291N	Neutral	0.035
NOTCH3	Q9UM47-1.2	R1291P	Neutral	0.424
NOTCH3	Q9UM47-1.2	R1291Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	R1291S	Neutral	0.131
NOTCH3	Q9UM47-1.2	R1291T	Neutral	0.14
NOTCH3	Q9UM47-1.2	R1291V	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	R1291W	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	R1291Y	Neutral	0.473
NOTCH3	Q9UM47-1.2	S1292A	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1292C	Neutral	0.089
NOTCH3	Q9UM47-1.2	S1292D	Neutral	0.021
NOTCH3	Q9UM47-1.2	S1292E	Neutral	0.019
NOTCH3	Q9UM47-1.2	S1292F	Neutral	0.27
NOTCH3	Q9UM47-1.2	S1292G	Neutral	0.02
NOTCH3	Q9UM47-1.2	S1292H	Neutral	0.079
NOTCH3	Q9UM47-1.2	S1292I	Neutral	0.278
NOTCH3	Q9UM47-1.2	S1292K	Neutral	0.017
NOTCH3	Q9UM47-1.2	S1292L	Neutral	0.278
NOTCH3	Q9UM47-1.2	S1292M	Neutral	0.078
NOTCH3	Q9UM47-1.2	S1292N	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1292P	Neutral	0.087
NOTCH3	Q9UM47-1.2	S1292Q	Neutral	0.019
NOTCH3	Q9UM47-1.2	S1292R	Neutral	0.071
NOTCH3	Q9UM47-1.2	S1292T	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1292V	Neutral	0.292
NOTCH3	Q9UM47-1.2	S1292W	Pathogenic	0.603
NOTCH3	Q9UM47-1.2	S1292Y	Neutral	0.264
NOTCH3	Q9UM47-1.2	C1293A	Neutral	0.474
NOTCH3	Q9UM47-1.2	C1293D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1293E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1293F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C1293G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1293H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1293I	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	C1293K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1293L	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	C1293M	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	C1293N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1293P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1293Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1293R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1293S	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1293T	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C1293V	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C1293W	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C1293Y	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	R1294A	Neutral	0.057
NOTCH3	Q9UM47-1.2	R1294C	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	R1294D	Neutral	0.23
NOTCH3	Q9UM47-1.2	R1294E	Neutral	0.015
NOTCH3	Q9UM47-1.2	R1294F	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	R1294G	Neutral	0.203
NOTCH3	Q9UM47-1.2	R1294H	Neutral	0.016
NOTCH3	Q9UM47-1.2	R1294I	Pathogenic	0.612
NOTCH3	Q9UM47-1.2	R1294K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1294L	Neutral	0.257
NOTCH3	Q9UM47-1.2	R1294M	Neutral	0.07
NOTCH3	Q9UM47-1.2	R1294N	Neutral	0.015
NOTCH3	Q9UM47-1.2	R1294P	Neutral	0.232
NOTCH3	Q9UM47-1.2	R1294Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R1294S	Neutral	0.058
NOTCH3	Q9UM47-1.2	R1294T	Neutral	0.063
NOTCH3	Q9UM47-1.2	R1294V	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	R1294W	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	R1294Y	Neutral	0.269
NOTCH3	Q9UM47-1.2	E1295A	Neutral	0.032
NOTCH3	Q9UM47-1.2	E1295C	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	E1295D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1295F	Neutral	0.421
NOTCH3	Q9UM47-1.2	E1295G	Neutral	0.121
NOTCH3	Q9UM47-1.2	E1295H	Neutral	0.008
NOTCH3	Q9UM47-1.2	E1295I	Neutral	0.431
NOTCH3	Q9UM47-1.2	E1295K	Neutral	0.002
NOTCH3	Q9UM47-1.2	E1295L	Neutral	0.431
NOTCH3	Q9UM47-1.2	E1295M	Neutral	0.142
NOTCH3	Q9UM47-1.2	E1295N	Neutral	0.008
NOTCH3	Q9UM47-1.2	E1295P	Neutral	0.034
NOTCH3	Q9UM47-1.2	E1295Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1295R	Neutral	0.007
NOTCH3	Q9UM47-1.2	E1295S	Neutral	0.007
NOTCH3	Q9UM47-1.2	E1295T	Neutral	0.035
NOTCH3	Q9UM47-1.2	E1295V	Neutral	0.148
NOTCH3	Q9UM47-1.2	E1295W	Neutral	0.396
NOTCH3	Q9UM47-1.2	E1295Y	Neutral	0.134
NOTCH3	Q9UM47-1.2	L1296A	Neutral	0.187
NOTCH3	Q9UM47-1.2	L1296C	Neutral	0.198
NOTCH3	Q9UM47-1.2	L1296D	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	L1296E	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	L1296F	Neutral	0.056
NOTCH3	Q9UM47-1.2	L1296G	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	L1296H	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	L1296I	Neutral	0.003
NOTCH3	Q9UM47-1.2	L1296K	Pathogenic	0.558
NOTCH3	Q9UM47-1.2	L1296M	Neutral	0.003
NOTCH3	Q9UM47-1.2	L1296N	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	L1296P	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	L1296Q	Pathogenic	0.558
NOTCH3	Q9UM47-1.2	L1296R	Pathogenic	0.546
NOTCH3	Q9UM47-1.2	L1296S	Pathogenic	0.518
NOTCH3	Q9UM47-1.2	L1296T	Neutral	0.203
NOTCH3	Q9UM47-1.2	L1296V	Neutral	0.013
NOTCH3	Q9UM47-1.2	L1296W	Pathogenic	0.527
NOTCH3	Q9UM47-1.2	L1296Y	Neutral	0.211
NOTCH3	Q9UM47-1.2	Q1297A	Neutral	0.014
NOTCH3	Q9UM47-1.2	Q1297C	Neutral	0.24
NOTCH3	Q9UM47-1.2	Q1297D	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q1297E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1297F	Neutral	0.247
NOTCH3	Q9UM47-1.2	Q1297G	Neutral	0.056
NOTCH3	Q9UM47-1.2	Q1297H	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q1297I	Neutral	0.255
NOTCH3	Q9UM47-1.2	Q1297K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1297L	Neutral	0.07
NOTCH3	Q9UM47-1.2	Q1297M	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q1297N	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q1297P	Neutral	0.015
NOTCH3	Q9UM47-1.2	Q1297R	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1297S	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q1297T	Neutral	0.015
NOTCH3	Q9UM47-1.2	Q1297V	Neutral	0.07
NOTCH3	Q9UM47-1.2	Q1297W	Neutral	0.061
NOTCH3	Q9UM47-1.2	Q1297Y	Neutral	0.015
NOTCH3	Q9UM47-1.2	C1298A	Neutral	0.458
NOTCH3	Q9UM47-1.2	C1298D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1298E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1298F	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	C1298G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1298H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1298I	Pathogenic	0.782
NOTCH3	Q9UM47-1.2	C1298K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1298L	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	C1298M	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	C1298N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1298P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1298Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1298R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1298S	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	C1298T	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	C1298V	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	C1298W	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	C1298Y	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	P1299A	Neutral	0.008
NOTCH3	Q9UM47-1.2	P1299C	Neutral	0.151
NOTCH3	Q9UM47-1.2	P1299D	Neutral	0.009
NOTCH3	Q9UM47-1.2	P1299E	Neutral	0.008
NOTCH3	Q9UM47-1.2	P1299F	Neutral	0.411
NOTCH3	Q9UM47-1.2	P1299G	Neutral	0.033
NOTCH3	Q9UM47-1.2	P1299H	Neutral	0.035
NOTCH3	Q9UM47-1.2	P1299I	Neutral	0.138
NOTCH3	Q9UM47-1.2	P1299K	Neutral	0.007
NOTCH3	Q9UM47-1.2	P1299L	Neutral	0.138
NOTCH3	Q9UM47-1.2	P1299M	Neutral	0.034
NOTCH3	Q9UM47-1.2	P1299N	Neutral	0.038
NOTCH3	Q9UM47-1.2	P1299Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	P1299R	Neutral	0.031
NOTCH3	Q9UM47-1.2	P1299S	Neutral	0.008
NOTCH3	Q9UM47-1.2	P1299T	Neutral	0.009
NOTCH3	Q9UM47-1.2	P1299V	Neutral	0.036
NOTCH3	Q9UM47-1.2	P1299W	Neutral	0.386
NOTCH3	Q9UM47-1.2	P1299Y	Neutral	0.13
NOTCH3	Q9UM47-1.2	V1300A	Neutral	0.004
NOTCH3	Q9UM47-1.2	V1300C	Neutral	0.018
NOTCH3	Q9UM47-1.2	V1300D	Neutral	0.278
NOTCH3	Q9UM47-1.2	V1300E	Neutral	0.081
NOTCH3	Q9UM47-1.2	V1300F	Neutral	0.017
NOTCH3	Q9UM47-1.2	V1300G	Neutral	0.245
NOTCH3	Q9UM47-1.2	V1300H	Neutral	0.277
NOTCH3	Q9UM47-1.2	V1300I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V1300K	Neutral	0.074
NOTCH3	Q9UM47-1.2	V1300L	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1300M	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1300N	Neutral	0.282
NOTCH3	Q9UM47-1.2	V1300P	Neutral	0.077
NOTCH3	Q9UM47-1.2	V1300Q	Neutral	0.079
NOTCH3	Q9UM47-1.2	V1300R	Neutral	0.257
NOTCH3	Q9UM47-1.2	V1300S	Neutral	0.073
NOTCH3	Q9UM47-1.2	V1300T	Neutral	0.004
NOTCH3	Q9UM47-1.2	V1300W	Neutral	0.244
NOTCH3	Q9UM47-1.2	V1300Y	Neutral	0.017
NOTCH3	Q9UM47-1.2	G1301A	Neutral	0.167
NOTCH3	Q9UM47-1.2	G1301C	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	G1301D	Neutral	0.455
NOTCH3	Q9UM47-1.2	G1301E	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	G1301F	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	G1301H	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	G1301I	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	G1301K	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	G1301L	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	G1301M	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	G1301N	Neutral	0.152
NOTCH3	Q9UM47-1.2	G1301P	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	G1301Q	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	G1301R	Pathogenic	0.753
NOTCH3	Q9UM47-1.2	G1301S	Neutral	0.163
NOTCH3	Q9UM47-1.2	G1301T	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	G1301V	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	G1301W	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	G1301Y	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	V1302A	Neutral	0.005
NOTCH3	Q9UM47-1.2	V1302C	Neutral	0.025
NOTCH3	Q9UM47-1.2	V1302D	Neutral	0.35
NOTCH3	Q9UM47-1.2	V1302E	Neutral	0.109
NOTCH3	Q9UM47-1.2	V1302F	Neutral	0.024
NOTCH3	Q9UM47-1.2	V1302G	Neutral	0.312
NOTCH3	Q9UM47-1.2	V1302H	Neutral	0.349
NOTCH3	Q9UM47-1.2	V1302I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V1302K	Neutral	0.1
NOTCH3	Q9UM47-1.2	V1302L	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1302M	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1302N	Neutral	0.354
NOTCH3	Q9UM47-1.2	V1302P	Neutral	0.104
NOTCH3	Q9UM47-1.2	V1302Q	Neutral	0.107
NOTCH3	Q9UM47-1.2	V1302R	Neutral	0.326
NOTCH3	Q9UM47-1.2	V1302S	Neutral	0.099
NOTCH3	Q9UM47-1.2	V1302T	Neutral	0.006
NOTCH3	Q9UM47-1.2	V1302W	Neutral	0.311
NOTCH3	Q9UM47-1.2	V1302Y	Neutral	0.023
NOTCH3	Q9UM47-1.2	P1303A	Neutral	0.007
NOTCH3	Q9UM47-1.2	P1303C	Neutral	0.142
NOTCH3	Q9UM47-1.2	P1303D	Neutral	0.008
NOTCH3	Q9UM47-1.2	P1303E	Neutral	0.008
NOTCH3	Q9UM47-1.2	P1303F	Neutral	0.394
NOTCH3	Q9UM47-1.2	P1303G	Neutral	0.031
NOTCH3	Q9UM47-1.2	P1303H	Neutral	0.032
NOTCH3	Q9UM47-1.2	P1303I	Neutral	0.13
NOTCH3	Q9UM47-1.2	P1303K	Neutral	0.007
NOTCH3	Q9UM47-1.2	P1303L	Neutral	0.13
NOTCH3	Q9UM47-1.2	P1303M	Neutral	0.032
NOTCH3	Q9UM47-1.2	P1303N	Neutral	0.035
NOTCH3	Q9UM47-1.2	P1303Q	Neutral	0.007
NOTCH3	Q9UM47-1.2	P1303R	Neutral	0.029
NOTCH3	Q9UM47-1.2	P1303S	Neutral	0.008
NOTCH3	Q9UM47-1.2	P1303T	Neutral	0.008
NOTCH3	Q9UM47-1.2	P1303V	Neutral	0.034
NOTCH3	Q9UM47-1.2	P1303W	Neutral	0.369
NOTCH3	Q9UM47-1.2	P1303Y	Neutral	0.122
NOTCH3	Q9UM47-1.2	C1304A	Neutral	0.479
NOTCH3	Q9UM47-1.2	C1304D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1304E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1304F	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	C1304G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1304H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1304I	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	C1304K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1304L	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	C1304M	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	C1304N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1304P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1304Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1304R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1304S	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C1304T	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C1304V	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	C1304W	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	C1304Y	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	Q1305A	Neutral	0.019
NOTCH3	Q9UM47-1.2	Q1305C	Neutral	0.306
NOTCH3	Q9UM47-1.2	Q1305D	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q1305E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1305F	Neutral	0.314
NOTCH3	Q9UM47-1.2	Q1305G	Neutral	0.077
NOTCH3	Q9UM47-1.2	Q1305H	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q1305I	Neutral	0.323
NOTCH3	Q9UM47-1.2	Q1305K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1305L	Neutral	0.095
NOTCH3	Q9UM47-1.2	Q1305M	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q1305N	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q1305P	Neutral	0.021
NOTCH3	Q9UM47-1.2	Q1305R	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1305S	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q1305T	Neutral	0.021
NOTCH3	Q9UM47-1.2	Q1305V	Neutral	0.095
NOTCH3	Q9UM47-1.2	Q1305W	Neutral	0.083
NOTCH3	Q9UM47-1.2	Q1305Y	Neutral	0.021
NOTCH3	Q9UM47-1.2	Q1306A	Neutral	0.027
NOTCH3	Q9UM47-1.2	Q1306C	Neutral	0.383
NOTCH3	Q9UM47-1.2	Q1306D	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q1306E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1306F	Neutral	0.391
NOTCH3	Q9UM47-1.2	Q1306G	Neutral	0.105
NOTCH3	Q9UM47-1.2	Q1306H	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q1306I	Neutral	0.402
NOTCH3	Q9UM47-1.2	Q1306K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1306L	Neutral	0.128
NOTCH3	Q9UM47-1.2	Q1306M	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q1306N	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q1306P	Neutral	0.03
NOTCH3	Q9UM47-1.2	Q1306R	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1306S	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q1306T	Neutral	0.03
NOTCH3	Q9UM47-1.2	Q1306V	Neutral	0.128
NOTCH3	Q9UM47-1.2	Q1306W	Neutral	0.113
NOTCH3	Q9UM47-1.2	Q1306Y	Neutral	0.029
NOTCH3	Q9UM47-1.2	T1307A	Neutral	0.036
NOTCH3	Q9UM47-1.2	T1307C	Neutral	0.155
NOTCH3	Q9UM47-1.2	T1307D	Neutral	0.158
NOTCH3	Q9UM47-1.2	T1307E	Neutral	0.151
NOTCH3	Q9UM47-1.2	T1307F	Neutral	0.423
NOTCH3	Q9UM47-1.2	T1307G	Neutral	0.418
NOTCH3	Q9UM47-1.2	T1307H	Neutral	0.437
NOTCH3	Q9UM47-1.2	T1307I	Neutral	0.144
NOTCH3	Q9UM47-1.2	T1307K	Neutral	0.139
NOTCH3	Q9UM47-1.2	T1307L	Neutral	0.144
NOTCH3	Q9UM47-1.2	T1307M	Neutral	0.144
NOTCH3	Q9UM47-1.2	T1307N	Neutral	0.039
NOTCH3	Q9UM47-1.2	T1307P	Neutral	0.157
NOTCH3	Q9UM47-1.2	T1307Q	Neutral	0.148
NOTCH3	Q9UM47-1.2	T1307R	Neutral	0.133
NOTCH3	Q9UM47-1.2	T1307S	Neutral	0.008
NOTCH3	Q9UM47-1.2	T1307V	Neutral	0.038
NOTCH3	Q9UM47-1.2	T1307W	Neutral	0.398
NOTCH3	Q9UM47-1.2	T1307Y	Neutral	0.416
NOTCH3	Q9UM47-1.2	P1308A	Neutral	0.02
NOTCH3	Q9UM47-1.2	P1308C	Neutral	0.311
NOTCH3	Q9UM47-1.2	P1308D	Neutral	0.022
NOTCH3	Q9UM47-1.2	P1308E	Neutral	0.02
NOTCH3	Q9UM47-1.2	P1308F	Pathogenic	0.638
NOTCH3	Q9UM47-1.2	P1308G	Neutral	0.079
NOTCH3	Q9UM47-1.2	P1308H	Neutral	0.083
NOTCH3	Q9UM47-1.2	P1308I	Neutral	0.288
NOTCH3	Q9UM47-1.2	P1308K	Neutral	0.018
NOTCH3	Q9UM47-1.2	P1308L	Neutral	0.288
NOTCH3	Q9UM47-1.2	P1308M	Neutral	0.081
NOTCH3	Q9UM47-1.2	P1308N	Neutral	0.09
NOTCH3	Q9UM47-1.2	P1308Q	Neutral	0.02
NOTCH3	Q9UM47-1.2	P1308R	Neutral	0.075
NOTCH3	Q9UM47-1.2	P1308S	Neutral	0.02
NOTCH3	Q9UM47-1.2	P1308T	Neutral	0.021
NOTCH3	Q9UM47-1.2	P1308V	Neutral	0.087
NOTCH3	Q9UM47-1.2	P1308W	Pathogenic	0.614
NOTCH3	Q9UM47-1.2	P1308Y	Neutral	0.273
NOTCH3	Q9UM47-1.2	R1309A	Neutral	0.087
NOTCH3	Q9UM47-1.2	R1309C	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	R1309D	Neutral	0.321
NOTCH3	Q9UM47-1.2	R1309E	Neutral	0.024
NOTCH3	Q9UM47-1.2	R1309F	Pathogenic	0.722
NOTCH3	Q9UM47-1.2	R1309G	Neutral	0.287
NOTCH3	Q9UM47-1.2	R1309H	Neutral	0.025
NOTCH3	Q9UM47-1.2	R1309I	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	R1309K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1309L	Neutral	0.354
NOTCH3	Q9UM47-1.2	R1309M	Neutral	0.107
NOTCH3	Q9UM47-1.2	R1309N	Neutral	0.023
NOTCH3	Q9UM47-1.2	R1309P	Neutral	0.323
NOTCH3	Q9UM47-1.2	R1309Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	R1309S	Neutral	0.089
NOTCH3	Q9UM47-1.2	R1309T	Neutral	0.095
NOTCH3	Q9UM47-1.2	R1309V	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	R1309W	Pathogenic	0.722
NOTCH3	Q9UM47-1.2	R1309Y	Neutral	0.368
NOTCH3	Q9UM47-1.2	G1310A	Neutral	0.058
NOTCH3	Q9UM47-1.2	G1310C	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	G1310D	Neutral	0.205
NOTCH3	Q9UM47-1.2	G1310E	Pathogenic	0.522
NOTCH3	Q9UM47-1.2	G1310F	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	G1310H	Pathogenic	0.512
NOTCH3	Q9UM47-1.2	G1310I	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G1310K	Neutral	0.498
NOTCH3	Q9UM47-1.2	G1310L	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G1310M	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	G1310N	Neutral	0.052
NOTCH3	Q9UM47-1.2	G1310P	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	G1310Q	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	G1310R	Neutral	0.485
NOTCH3	Q9UM47-1.2	G1310S	Neutral	0.057
NOTCH3	Q9UM47-1.2	G1310T	Pathogenic	0.536
NOTCH3	Q9UM47-1.2	G1310V	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G1310W	Neutral	0.473
NOTCH3	Q9UM47-1.2	G1310Y	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	P1311A	Neutral	0.232
NOTCH3	Q9UM47-1.2	P1311C	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	P1311D	Neutral	0.25
NOTCH3	Q9UM47-1.2	P1311E	Neutral	0.237
NOTCH3	Q9UM47-1.2	P1311F	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	P1311G	Pathogenic	0.562
NOTCH3	Q9UM47-1.2	P1311H	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	P1311I	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	P1311K	Neutral	0.219
NOTCH3	Q9UM47-1.2	P1311L	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	P1311M	Pathogenic	0.569
NOTCH3	Q9UM47-1.2	P1311N	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	P1311Q	Neutral	0.233
NOTCH3	Q9UM47-1.2	P1311R	Pathogenic	0.549
NOTCH3	Q9UM47-1.2	P1311S	Neutral	0.237
NOTCH3	Q9UM47-1.2	P1311T	Neutral	0.247
NOTCH3	Q9UM47-1.2	P1311V	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	P1311W	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	P1311Y	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	R1312A	Neutral	0.282
NOTCH3	Q9UM47-1.2	R1312C	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	R1312D	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	R1312E	Neutral	0.091
NOTCH3	Q9UM47-1.2	R1312F	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	R1312G	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	R1312H	Neutral	0.095
NOTCH3	Q9UM47-1.2	R1312I	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	R1312K	Neutral	0.005
NOTCH3	Q9UM47-1.2	R1312L	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	R1312M	Neutral	0.33
NOTCH3	Q9UM47-1.2	R1312N	Neutral	0.087
NOTCH3	Q9UM47-1.2	R1312P	Pathogenic	0.662
NOTCH3	Q9UM47-1.2	R1312Q	Neutral	0.022
NOTCH3	Q9UM47-1.2	R1312S	Neutral	0.286
NOTCH3	Q9UM47-1.2	R1312T	Neutral	0.302
NOTCH3	Q9UM47-1.2	R1312V	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	R1312W	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	R1312Y	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	C1313A	Neutral	0.472
NOTCH3	Q9UM47-1.2	C1313D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1313E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1313F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C1313G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1313H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1313I	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	C1313K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1313L	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	C1313M	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C1313N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1313P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1313Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1313R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1313S	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C1313T	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C1313V	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C1313W	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C1313Y	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	A1314C	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1314D	Neutral	0.029
NOTCH3	Q9UM47-1.2	A1314E	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1314F	Neutral	0.025
NOTCH3	Q9UM47-1.2	A1314G	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1314H	Neutral	0.026
NOTCH3	Q9UM47-1.2	A1314I	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1314K	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1314L	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1314M	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1314N	Neutral	0.028
NOTCH3	Q9UM47-1.2	A1314P	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1314Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1314R	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1314S	Neutral	0.0
NOTCH3	Q9UM47-1.2	A1314T	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1314V	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1314W	Neutral	0.094
NOTCH3	Q9UM47-1.2	A1314Y	Neutral	0.024
NOTCH3	Q9UM47-1.2	C1315A	Neutral	0.453
NOTCH3	Q9UM47-1.2	C1315D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1315E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1315F	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	C1315G	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1315H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1315I	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	C1315K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1315L	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	C1315M	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	C1315N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1315P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1315Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1315R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C1315S	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	C1315T	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	C1315V	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C1315W	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	C1315Y	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	P1316A	Neutral	0.139
NOTCH3	Q9UM47-1.2	P1316C	Pathogenic	0.782
NOTCH3	Q9UM47-1.2	P1316D	Neutral	0.15
NOTCH3	Q9UM47-1.2	P1316E	Neutral	0.141
NOTCH3	Q9UM47-1.2	P1316F	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	P1316G	Neutral	0.406
NOTCH3	Q9UM47-1.2	P1316H	Neutral	0.418
NOTCH3	Q9UM47-1.2	P1316I	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	P1316K	Neutral	0.13
NOTCH3	Q9UM47-1.2	P1316L	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	P1316M	Neutral	0.413
NOTCH3	Q9UM47-1.2	P1316N	Neutral	0.441
NOTCH3	Q9UM47-1.2	P1316Q	Neutral	0.139
NOTCH3	Q9UM47-1.2	P1316R	Neutral	0.393
NOTCH3	Q9UM47-1.2	P1316S	Neutral	0.142
NOTCH3	Q9UM47-1.2	P1316T	Neutral	0.148
NOTCH3	Q9UM47-1.2	P1316V	Neutral	0.431
NOTCH3	Q9UM47-1.2	P1316W	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	P1316Y	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	P1317A	Neutral	0.036
NOTCH3	Q9UM47-1.2	P1317C	Neutral	0.451
NOTCH3	Q9UM47-1.2	P1317D	Neutral	0.039
NOTCH3	Q9UM47-1.2	P1317E	Neutral	0.036
NOTCH3	Q9UM47-1.2	P1317F	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	P1317G	Neutral	0.135
NOTCH3	Q9UM47-1.2	P1317H	Neutral	0.141
NOTCH3	Q9UM47-1.2	P1317I	Neutral	0.424
NOTCH3	Q9UM47-1.2	P1317K	Neutral	0.033
NOTCH3	Q9UM47-1.2	P1317L	Neutral	0.424
NOTCH3	Q9UM47-1.2	P1317M	Neutral	0.139
NOTCH3	Q9UM47-1.2	P1317N	Neutral	0.153
NOTCH3	Q9UM47-1.2	P1317Q	Neutral	0.036
NOTCH3	Q9UM47-1.2	P1317R	Neutral	0.129
NOTCH3	Q9UM47-1.2	P1317S	Neutral	0.036
NOTCH3	Q9UM47-1.2	P1317T	Neutral	0.038
NOTCH3	Q9UM47-1.2	P1317V	Neutral	0.148
NOTCH3	Q9UM47-1.2	P1317W	Pathogenic	0.743
NOTCH3	Q9UM47-1.2	P1317Y	Neutral	0.406
NOTCH3	Q9UM47-1.2	G1318A	Neutral	0.008
NOTCH3	Q9UM47-1.2	G1318C	Neutral	0.42
NOTCH3	Q9UM47-1.2	G1318D	Neutral	0.033
NOTCH3	Q9UM47-1.2	G1318E	Neutral	0.127
NOTCH3	Q9UM47-1.2	G1318F	Neutral	0.376
NOTCH3	Q9UM47-1.2	G1318H	Neutral	0.123
NOTCH3	Q9UM47-1.2	G1318I	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	G1318K	Neutral	0.116
NOTCH3	Q9UM47-1.2	G1318L	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	G1318M	Neutral	0.385
NOTCH3	Q9UM47-1.2	G1318N	Neutral	0.007
NOTCH3	Q9UM47-1.2	G1318P	Neutral	0.135
NOTCH3	Q9UM47-1.2	G1318Q	Neutral	0.124
NOTCH3	Q9UM47-1.2	G1318R	Neutral	0.111
NOTCH3	Q9UM47-1.2	G1318S	Neutral	0.008
NOTCH3	Q9UM47-1.2	G1318T	Neutral	0.133
NOTCH3	Q9UM47-1.2	G1318V	Neutral	0.403
NOTCH3	Q9UM47-1.2	G1318W	Neutral	0.107
NOTCH3	Q9UM47-1.2	G1318Y	Neutral	0.369
NOTCH3	Q9UM47-1.2	L1319A	Neutral	0.01
NOTCH3	Q9UM47-1.2	L1319C	Neutral	0.011
NOTCH3	Q9UM47-1.2	L1319D	Pathogenic	0.521
NOTCH3	Q9UM47-1.2	L1319E	Neutral	0.204
NOTCH3	Q9UM47-1.2	L1319F	Neutral	0.003
NOTCH3	Q9UM47-1.2	L1319G	Neutral	0.478
NOTCH3	Q9UM47-1.2	L1319H	Neutral	0.208
NOTCH3	Q9UM47-1.2	L1319I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1319K	Neutral	0.054
NOTCH3	Q9UM47-1.2	L1319M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1319N	Neutral	0.196
NOTCH3	Q9UM47-1.2	L1319P	Neutral	0.19
NOTCH3	Q9UM47-1.2	L1319Q	Neutral	0.054
NOTCH3	Q9UM47-1.2	L1319R	Neutral	0.052
NOTCH3	Q9UM47-1.2	L1319S	Neutral	0.046
NOTCH3	Q9UM47-1.2	L1319T	Neutral	0.011
NOTCH3	Q9UM47-1.2	L1319V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1319W	Neutral	0.048
NOTCH3	Q9UM47-1.2	L1319Y	Neutral	0.012
NOTCH3	Q9UM47-1.2	S1320A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1320C	Neutral	0.022
NOTCH3	Q9UM47-1.2	S1320D	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1320E	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1320F	Neutral	0.078
NOTCH3	Q9UM47-1.2	S1320G	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1320H	Neutral	0.019
NOTCH3	Q9UM47-1.2	S1320I	Neutral	0.082
NOTCH3	Q9UM47-1.2	S1320K	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1320L	Neutral	0.081
NOTCH3	Q9UM47-1.2	S1320M	Neutral	0.019
NOTCH3	Q9UM47-1.2	S1320N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1320P	Neutral	0.022
NOTCH3	Q9UM47-1.2	S1320Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1320R	Neutral	0.017
NOTCH3	Q9UM47-1.2	S1320T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1320V	Neutral	0.087
NOTCH3	Q9UM47-1.2	S1320W	Neutral	0.259
NOTCH3	Q9UM47-1.2	S1320Y	Neutral	0.076
NOTCH3	Q9UM47-1.2	G1321A	Neutral	0.111
NOTCH3	Q9UM47-1.2	G1321C	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	G1321D	Neutral	0.342
NOTCH3	Q9UM47-1.2	G1321E	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	G1321F	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	G1321H	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	G1321I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	G1321K	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	G1321L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	G1321M	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	G1321N	Neutral	0.101
NOTCH3	Q9UM47-1.2	G1321P	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	G1321Q	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	G1321R	Pathogenic	0.656
NOTCH3	Q9UM47-1.2	G1321S	Neutral	0.108
NOTCH3	Q9UM47-1.2	G1321T	Pathogenic	0.701
NOTCH3	Q9UM47-1.2	G1321V	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	G1321W	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	G1321Y	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	P1322A	Neutral	0.104
NOTCH3	Q9UM47-1.2	P1322C	Pathogenic	0.72
NOTCH3	Q9UM47-1.2	P1322D	Neutral	0.113
NOTCH3	Q9UM47-1.2	P1322E	Neutral	0.106
NOTCH3	Q9UM47-1.2	P1322F	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	P1322G	Neutral	0.329
NOTCH3	Q9UM47-1.2	P1322H	Neutral	0.341
NOTCH3	Q9UM47-1.2	P1322I	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	P1322K	Neutral	0.097
NOTCH3	Q9UM47-1.2	P1322L	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	P1322M	Neutral	0.335
NOTCH3	Q9UM47-1.2	P1322N	Neutral	0.361
NOTCH3	Q9UM47-1.2	P1322Q	Neutral	0.104
NOTCH3	Q9UM47-1.2	P1322R	Neutral	0.317
NOTCH3	Q9UM47-1.2	P1322S	Neutral	0.106
NOTCH3	Q9UM47-1.2	P1322T	Neutral	0.111
NOTCH3	Q9UM47-1.2	P1322V	Neutral	0.352
NOTCH3	Q9UM47-1.2	P1322W	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	P1322Y	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	S1323A	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1323C	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1323D	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1323E	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1323F	Neutral	0.01
NOTCH3	Q9UM47-1.2	S1323G	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1323H	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1323I	Neutral	0.011
NOTCH3	Q9UM47-1.2	S1323K	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1323L	Neutral	0.011
NOTCH3	Q9UM47-1.2	S1323M	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1323N	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1323P	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1323Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1323R	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1323T	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1323V	Neutral	0.011
NOTCH3	Q9UM47-1.2	S1323W	Neutral	0.04
NOTCH3	Q9UM47-1.2	S1323Y	Neutral	0.01
NOTCH3	Q9UM47-1.2	C1324A	Neutral	0.49
NOTCH3	Q9UM47-1.2	C1324D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1324E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1324F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C1324G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1324H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1324I	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C1324K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1324L	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C1324M	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C1324N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1324P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1324Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1324R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1324S	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C1324T	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	C1324V	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C1324W	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	C1324Y	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	R1325A	Neutral	0.047
NOTCH3	Q9UM47-1.2	R1325C	Pathogenic	0.527
NOTCH3	Q9UM47-1.2	R1325D	Neutral	0.197
NOTCH3	Q9UM47-1.2	R1325E	Neutral	0.013
NOTCH3	Q9UM47-1.2	R1325F	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	R1325G	Neutral	0.173
NOTCH3	Q9UM47-1.2	R1325H	Neutral	0.013
NOTCH3	Q9UM47-1.2	R1325I	Pathogenic	0.565
NOTCH3	Q9UM47-1.2	R1325K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1325L	Neutral	0.222
NOTCH3	Q9UM47-1.2	R1325M	Neutral	0.059
NOTCH3	Q9UM47-1.2	R1325N	Neutral	0.012
NOTCH3	Q9UM47-1.2	R1325P	Neutral	0.199
NOTCH3	Q9UM47-1.2	R1325Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R1325S	Neutral	0.048
NOTCH3	Q9UM47-1.2	R1325T	Neutral	0.052
NOTCH3	Q9UM47-1.2	R1325V	Pathogenic	0.546
NOTCH3	Q9UM47-1.2	R1325W	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	R1325Y	Neutral	0.232
NOTCH3	Q9UM47-1.2	S1326A	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1326C	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1326D	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1326E	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1326F	Neutral	0.013
NOTCH3	Q9UM47-1.2	S1326G	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1326H	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1326I	Neutral	0.013
NOTCH3	Q9UM47-1.2	S1326K	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1326L	Neutral	0.013
NOTCH3	Q9UM47-1.2	S1326M	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1326N	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1326P	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1326Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1326R	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1326T	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1326V	Neutral	0.014
NOTCH3	Q9UM47-1.2	S1326W	Neutral	0.05
NOTCH3	Q9UM47-1.2	S1326Y	Neutral	0.012
NOTCH3	Q9UM47-1.2	F1327A	Neutral	0.077
NOTCH3	Q9UM47-1.2	F1327C	Neutral	0.082
NOTCH3	Q9UM47-1.2	F1327D	Neutral	0.296
NOTCH3	Q9UM47-1.2	F1327E	Neutral	0.31
NOTCH3	Q9UM47-1.2	F1327G	Neutral	0.261
NOTCH3	Q9UM47-1.2	F1327H	Neutral	0.022
NOTCH3	Q9UM47-1.2	F1327I	Neutral	0.005
NOTCH3	Q9UM47-1.2	F1327K	Neutral	0.333
NOTCH3	Q9UM47-1.2	F1327L	Neutral	0.005
NOTCH3	Q9UM47-1.2	F1327M	Neutral	0.005
NOTCH3	Q9UM47-1.2	F1327N	Neutral	0.299
NOTCH3	Q9UM47-1.2	F1327P	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	F1327Q	Neutral	0.314
NOTCH3	Q9UM47-1.2	F1327R	Neutral	0.322
NOTCH3	Q9UM47-1.2	F1327S	Neutral	0.079
NOTCH3	Q9UM47-1.2	F1327T	Neutral	0.084
NOTCH3	Q9UM47-1.2	F1327V	Neutral	0.021
NOTCH3	Q9UM47-1.2	F1327W	Neutral	0.001
NOTCH3	Q9UM47-1.2	F1327Y	Neutral	0.0
NOTCH3	Q9UM47-1.2	P1328A	Neutral	0.001
NOTCH3	Q9UM47-1.2	P1328C	Neutral	0.012
NOTCH3	Q9UM47-1.2	P1328D	Neutral	0.001
NOTCH3	Q9UM47-1.2	P1328E	Neutral	0.001
NOTCH3	Q9UM47-1.2	P1328F	Neutral	0.046
NOTCH3	Q9UM47-1.2	P1328G	Neutral	0.002
NOTCH3	Q9UM47-1.2	P1328H	Neutral	0.002
NOTCH3	Q9UM47-1.2	P1328I	Neutral	0.011
NOTCH3	Q9UM47-1.2	P1328K	Neutral	0.001
NOTCH3	Q9UM47-1.2	P1328L	Neutral	0.011
NOTCH3	Q9UM47-1.2	P1328M	Neutral	0.002
NOTCH3	Q9UM47-1.2	P1328N	Neutral	0.003
NOTCH3	Q9UM47-1.2	P1328Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	P1328R	Neutral	0.002
NOTCH3	Q9UM47-1.2	P1328S	Neutral	0.001
NOTCH3	Q9UM47-1.2	P1328T	Neutral	0.001
NOTCH3	Q9UM47-1.2	P1328V	Neutral	0.003
NOTCH3	Q9UM47-1.2	P1328W	Neutral	0.042
NOTCH3	Q9UM47-1.2	P1328Y	Neutral	0.01
NOTCH3	Q9UM47-1.2	G1329A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1329C	Neutral	0.174
NOTCH3	Q9UM47-1.2	G1329D	Neutral	0.01
NOTCH3	Q9UM47-1.2	G1329E	Neutral	0.041
NOTCH3	Q9UM47-1.2	G1329F	Neutral	0.15
NOTCH3	Q9UM47-1.2	G1329H	Neutral	0.039
NOTCH3	Q9UM47-1.2	G1329I	Neutral	0.455
NOTCH3	Q9UM47-1.2	G1329K	Neutral	0.037
NOTCH3	Q9UM47-1.2	G1329L	Neutral	0.455
NOTCH3	Q9UM47-1.2	G1329M	Neutral	0.154
NOTCH3	Q9UM47-1.2	G1329N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1329P	Neutral	0.044
NOTCH3	Q9UM47-1.2	G1329Q	Neutral	0.04
NOTCH3	Q9UM47-1.2	G1329R	Neutral	0.035
NOTCH3	Q9UM47-1.2	G1329S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1329T	Neutral	0.043
NOTCH3	Q9UM47-1.2	G1329V	Neutral	0.164
NOTCH3	Q9UM47-1.2	G1329W	Neutral	0.034
NOTCH3	Q9UM47-1.2	G1329Y	Neutral	0.146
NOTCH3	Q9UM47-1.2	S1330A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1330C	Neutral	0.027
NOTCH3	Q9UM47-1.2	S1330D	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1330E	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1330F	Neutral	0.095
NOTCH3	Q9UM47-1.2	S1330G	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1330H	Neutral	0.024
NOTCH3	Q9UM47-1.2	S1330I	Neutral	0.099
NOTCH3	Q9UM47-1.2	S1330K	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1330L	Neutral	0.099
NOTCH3	Q9UM47-1.2	S1330M	Neutral	0.023
NOTCH3	Q9UM47-1.2	S1330N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1330P	Neutral	0.026
NOTCH3	Q9UM47-1.2	S1330Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1330R	Neutral	0.021
NOTCH3	Q9UM47-1.2	S1330T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1330V	Neutral	0.105
NOTCH3	Q9UM47-1.2	S1330W	Neutral	0.301
NOTCH3	Q9UM47-1.2	S1330Y	Neutral	0.092
NOTCH3	Q9UM47-1.2	P1331A	Neutral	0.022
NOTCH3	Q9UM47-1.2	P1331C	Neutral	0.338
NOTCH3	Q9UM47-1.2	P1331D	Neutral	0.025
NOTCH3	Q9UM47-1.2	P1331E	Neutral	0.023
NOTCH3	Q9UM47-1.2	P1331F	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	P1331G	Neutral	0.088
NOTCH3	Q9UM47-1.2	P1331H	Neutral	0.093
NOTCH3	Q9UM47-1.2	P1331I	Neutral	0.314
NOTCH3	Q9UM47-1.2	P1331K	Neutral	0.021
NOTCH3	Q9UM47-1.2	P1331L	Neutral	0.314
NOTCH3	Q9UM47-1.2	P1331M	Neutral	0.091
NOTCH3	Q9UM47-1.2	P1331N	Neutral	0.101
NOTCH3	Q9UM47-1.2	P1331Q	Neutral	0.022
NOTCH3	Q9UM47-1.2	P1331R	Neutral	0.084
NOTCH3	Q9UM47-1.2	P1331S	Neutral	0.023
NOTCH3	Q9UM47-1.2	P1331T	Neutral	0.024
NOTCH3	Q9UM47-1.2	P1331V	Neutral	0.097
NOTCH3	Q9UM47-1.2	P1331W	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	P1331Y	Neutral	0.298
NOTCH3	Q9UM47-1.2	P1332A	Neutral	0.014
NOTCH3	Q9UM47-1.2	P1332C	Neutral	0.234
NOTCH3	Q9UM47-1.2	P1332D	Neutral	0.015
NOTCH3	Q9UM47-1.2	P1332E	Neutral	0.014
NOTCH3	Q9UM47-1.2	P1332F	Pathogenic	0.544
NOTCH3	Q9UM47-1.2	P1332G	Neutral	0.055
NOTCH3	Q9UM47-1.2	P1332H	Neutral	0.058
NOTCH3	Q9UM47-1.2	P1332I	Neutral	0.215
NOTCH3	Q9UM47-1.2	P1332K	Neutral	0.013
NOTCH3	Q9UM47-1.2	P1332L	Neutral	0.215
NOTCH3	Q9UM47-1.2	P1332M	Neutral	0.057
NOTCH3	Q9UM47-1.2	P1332N	Neutral	0.063
NOTCH3	Q9UM47-1.2	P1332Q	Neutral	0.014
NOTCH3	Q9UM47-1.2	P1332R	Neutral	0.052
NOTCH3	Q9UM47-1.2	P1332S	Neutral	0.014
NOTCH3	Q9UM47-1.2	P1332T	Neutral	0.015
NOTCH3	Q9UM47-1.2	P1332V	Neutral	0.061
NOTCH3	Q9UM47-1.2	P1332W	Pathogenic	0.519
NOTCH3	Q9UM47-1.2	P1332Y	Neutral	0.203
NOTCH3	Q9UM47-1.2	G1333A	Neutral	0.001
NOTCH3	Q9UM47-1.2	G1333C	Neutral	0.064
NOTCH3	Q9UM47-1.2	G1333D	Neutral	0.003
NOTCH3	Q9UM47-1.2	G1333E	Neutral	0.013
NOTCH3	Q9UM47-1.2	G1333F	Neutral	0.054
NOTCH3	Q9UM47-1.2	G1333H	Neutral	0.013
NOTCH3	Q9UM47-1.2	G1333I	Neutral	0.213
NOTCH3	Q9UM47-1.2	G1333K	Neutral	0.012
NOTCH3	Q9UM47-1.2	G1333L	Neutral	0.213
NOTCH3	Q9UM47-1.2	G1333M	Neutral	0.056
NOTCH3	Q9UM47-1.2	G1333N	Neutral	0.001
NOTCH3	Q9UM47-1.2	G1333P	Neutral	0.015
NOTCH3	Q9UM47-1.2	G1333Q	Neutral	0.013
NOTCH3	Q9UM47-1.2	G1333R	Neutral	0.012
NOTCH3	Q9UM47-1.2	G1333S	Neutral	0.001
NOTCH3	Q9UM47-1.2	G1333T	Neutral	0.014
NOTCH3	Q9UM47-1.2	G1333V	Neutral	0.06
NOTCH3	Q9UM47-1.2	G1333W	Neutral	0.011
NOTCH3	Q9UM47-1.2	G1333Y	Neutral	0.052
NOTCH3	Q9UM47-1.2	A1334C	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1334D	Neutral	0.031
NOTCH3	Q9UM47-1.2	A1334E	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1334F	Neutral	0.027
NOTCH3	Q9UM47-1.2	A1334G	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1334H	Neutral	0.028
NOTCH3	Q9UM47-1.2	A1334I	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1334K	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1334L	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1334M	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1334N	Neutral	0.031
NOTCH3	Q9UM47-1.2	A1334P	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1334Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1334R	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1334S	Neutral	0.0
NOTCH3	Q9UM47-1.2	A1334T	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1334V	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1334W	Neutral	0.101
NOTCH3	Q9UM47-1.2	A1334Y	Neutral	0.026
NOTCH3	Q9UM47-1.2	S1335A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1335C	Neutral	0.016
NOTCH3	Q9UM47-1.2	S1335D	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1335E	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1335F	Neutral	0.058
NOTCH3	Q9UM47-1.2	S1335G	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1335H	Neutral	0.014
NOTCH3	Q9UM47-1.2	S1335I	Neutral	0.06
NOTCH3	Q9UM47-1.2	S1335K	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1335L	Neutral	0.06
NOTCH3	Q9UM47-1.2	S1335M	Neutral	0.014
NOTCH3	Q9UM47-1.2	S1335N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1335P	Neutral	0.016
NOTCH3	Q9UM47-1.2	S1335Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1335R	Neutral	0.013
NOTCH3	Q9UM47-1.2	S1335T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1335V	Neutral	0.064
NOTCH3	Q9UM47-1.2	S1335W	Neutral	0.2
NOTCH3	Q9UM47-1.2	S1335Y	Neutral	0.056
NOTCH3	Q9UM47-1.2	N1336A	Neutral	0.281
NOTCH3	Q9UM47-1.2	N1336C	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	N1336D	Neutral	0.004
NOTCH3	Q9UM47-1.2	N1336E	Neutral	0.019
NOTCH3	Q9UM47-1.2	N1336F	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	N1336G	Neutral	0.017
NOTCH3	Q9UM47-1.2	N1336H	Neutral	0.004
NOTCH3	Q9UM47-1.2	N1336I	Pathogenic	0.643
NOTCH3	Q9UM47-1.2	N1336K	Neutral	0.018
NOTCH3	Q9UM47-1.2	N1336L	Pathogenic	0.643
NOTCH3	Q9UM47-1.2	N1336M	Neutral	0.283
NOTCH3	Q9UM47-1.2	N1336P	Neutral	0.3
NOTCH3	Q9UM47-1.2	N1336Q	Neutral	0.019
NOTCH3	Q9UM47-1.2	N1336R	Neutral	0.017
NOTCH3	Q9UM47-1.2	N1336S	Neutral	0.004
NOTCH3	Q9UM47-1.2	N1336T	Neutral	0.02
NOTCH3	Q9UM47-1.2	N1336V	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	N1336W	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	N1336Y	Neutral	0.269
NOTCH3	Q9UM47-1.2	A1337C	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1337D	Neutral	0.032
NOTCH3	Q9UM47-1.2	A1337E	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1337F	Neutral	0.027
NOTCH3	Q9UM47-1.2	A1337G	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1337H	Neutral	0.029
NOTCH3	Q9UM47-1.2	A1337I	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1337K	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1337L	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1337M	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1337N	Neutral	0.031
NOTCH3	Q9UM47-1.2	A1337P	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1337Q	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1337R	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1337S	Neutral	0.0
NOTCH3	Q9UM47-1.2	A1337T	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1337V	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1337W	Neutral	0.103
NOTCH3	Q9UM47-1.2	A1337Y	Neutral	0.026
NOTCH3	Q9UM47-1.2	S1338A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1338C	Neutral	0.011
NOTCH3	Q9UM47-1.2	S1338D	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1338E	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1338F	Neutral	0.04
NOTCH3	Q9UM47-1.2	S1338G	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1338H	Neutral	0.01
NOTCH3	Q9UM47-1.2	S1338I	Neutral	0.042
NOTCH3	Q9UM47-1.2	S1338K	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1338L	Neutral	0.041
NOTCH3	Q9UM47-1.2	S1338M	Neutral	0.009
NOTCH3	Q9UM47-1.2	S1338N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1338P	Neutral	0.011
NOTCH3	Q9UM47-1.2	S1338Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1338R	Neutral	0.009
NOTCH3	Q9UM47-1.2	S1338T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1338V	Neutral	0.044
NOTCH3	Q9UM47-1.2	S1338W	Neutral	0.146
NOTCH3	Q9UM47-1.2	S1338Y	Neutral	0.039
NOTCH3	Q9UM47-1.2	C1339A	Neutral	0.475
NOTCH3	Q9UM47-1.2	C1339D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1339E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1339F	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	C1339G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1339H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1339I	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	C1339K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1339L	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	C1339M	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	C1339N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1339P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1339Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1339R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1339S	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C1339T	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	C1339V	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C1339W	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	C1339Y	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	A1340C	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1340D	Neutral	0.179
NOTCH3	Q9UM47-1.2	A1340E	Neutral	0.043
NOTCH3	Q9UM47-1.2	A1340F	Neutral	0.156
NOTCH3	Q9UM47-1.2	A1340G	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1340H	Neutral	0.164
NOTCH3	Q9UM47-1.2	A1340I	Neutral	0.041
NOTCH3	Q9UM47-1.2	A1340K	Neutral	0.039
NOTCH3	Q9UM47-1.2	A1340L	Neutral	0.041
NOTCH3	Q9UM47-1.2	A1340M	Neutral	0.041
NOTCH3	Q9UM47-1.2	A1340N	Neutral	0.176
NOTCH3	Q9UM47-1.2	A1340P	Neutral	0.046
NOTCH3	Q9UM47-1.2	A1340Q	Neutral	0.042
NOTCH3	Q9UM47-1.2	A1340R	Neutral	0.037
NOTCH3	Q9UM47-1.2	A1340S	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1340T	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1340V	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1340W	Neutral	0.432
NOTCH3	Q9UM47-1.2	A1340Y	Neutral	0.152
NOTCH3	Q9UM47-1.2	A1341C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1341D	Neutral	0.051
NOTCH3	Q9UM47-1.2	A1341E	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1341F	Neutral	0.043
NOTCH3	Q9UM47-1.2	A1341G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1341H	Neutral	0.045
NOTCH3	Q9UM47-1.2	A1341I	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1341K	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1341L	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1341M	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1341N	Neutral	0.05
NOTCH3	Q9UM47-1.2	A1341P	Neutral	0.012
NOTCH3	Q9UM47-1.2	A1341Q	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1341R	Neutral	0.009
NOTCH3	Q9UM47-1.2	A1341S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1341T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1341V	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1341W	Neutral	0.156
NOTCH3	Q9UM47-1.2	A1341Y	Neutral	0.042
NOTCH3	Q9UM47-1.2	A1342C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1342D	Neutral	0.052
NOTCH3	Q9UM47-1.2	A1342E	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1342F	Neutral	0.044
NOTCH3	Q9UM47-1.2	A1342G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1342H	Neutral	0.047
NOTCH3	Q9UM47-1.2	A1342I	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1342K	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1342L	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1342M	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1342N	Neutral	0.051
NOTCH3	Q9UM47-1.2	A1342P	Neutral	0.012
NOTCH3	Q9UM47-1.2	A1342Q	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1342R	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1342S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1342T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1342V	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1342W	Neutral	0.159
NOTCH3	Q9UM47-1.2	A1342Y	Neutral	0.043
NOTCH3	Q9UM47-1.2	P1343A	Pathogenic	0.571
NOTCH3	Q9UM47-1.2	P1343C	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	P1343D	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	P1343E	Pathogenic	0.576
NOTCH3	Q9UM47-1.2	P1343F	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	P1343G	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	P1343H	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	P1343I	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	P1343K	Pathogenic	0.552
NOTCH3	Q9UM47-1.2	P1343L	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	P1343M	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	P1343N	Pathogenic	0.867
NOTCH3	Q9UM47-1.2	P1343Q	Pathogenic	0.571
NOTCH3	Q9UM47-1.2	P1343R	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	P1343S	Pathogenic	0.577
NOTCH3	Q9UM47-1.2	P1343T	Pathogenic	0.589
NOTCH3	Q9UM47-1.2	P1343V	Pathogenic	0.862
NOTCH3	Q9UM47-1.2	P1343W	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	P1343Y	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	C1344A	Neutral	0.461
NOTCH3	Q9UM47-1.2	C1344D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1344E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1344F	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	C1344G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1344H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1344I	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	C1344K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1344L	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	C1344M	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	C1344N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1344P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1344Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1344R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1344S	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	C1344T	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C1344V	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	C1344W	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	C1344Y	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	L1345A	Neutral	0.016
NOTCH3	Q9UM47-1.2	L1345C	Neutral	0.017
NOTCH3	Q9UM47-1.2	L1345D	Pathogenic	0.631
NOTCH3	Q9UM47-1.2	L1345E	Neutral	0.287
NOTCH3	Q9UM47-1.2	L1345F	Neutral	0.004
NOTCH3	Q9UM47-1.2	L1345G	Pathogenic	0.59
NOTCH3	Q9UM47-1.2	L1345H	Neutral	0.293
NOTCH3	Q9UM47-1.2	L1345I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1345K	Neutral	0.083
NOTCH3	Q9UM47-1.2	L1345M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1345N	Neutral	0.277
NOTCH3	Q9UM47-1.2	L1345P	Neutral	0.27
NOTCH3	Q9UM47-1.2	L1345Q	Neutral	0.082
NOTCH3	Q9UM47-1.2	L1345R	Neutral	0.079
NOTCH3	Q9UM47-1.2	L1345S	Neutral	0.071
NOTCH3	Q9UM47-1.2	L1345T	Neutral	0.018
NOTCH3	Q9UM47-1.2	L1345V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1345W	Neutral	0.073
NOTCH3	Q9UM47-1.2	L1345Y	Neutral	0.019
NOTCH3	Q9UM47-1.2	H1346A	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	H1346C	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	H1346D	Neutral	0.372
NOTCH3	Q9UM47-1.2	H1346E	Neutral	0.122
NOTCH3	Q9UM47-1.2	H1346F	Neutral	0.383
NOTCH3	Q9UM47-1.2	H1346G	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	H1346I	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	H1346K	Neutral	0.382
NOTCH3	Q9UM47-1.2	H1346L	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	H1346M	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	H1346N	Neutral	0.028
NOTCH3	Q9UM47-1.2	H1346P	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	H1346Q	Neutral	0.124
NOTCH3	Q9UM47-1.2	H1346R	Neutral	0.114
NOTCH3	Q9UM47-1.2	H1346S	Neutral	0.355
NOTCH3	Q9UM47-1.2	H1346T	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	H1346V	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	H1346W	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	H1346Y	Neutral	0.006
NOTCH3	Q9UM47-1.2	G1347A	Neutral	0.058
NOTCH3	Q9UM47-1.2	G1347C	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	G1347D	Neutral	0.205
NOTCH3	Q9UM47-1.2	G1347E	Pathogenic	0.523
NOTCH3	Q9UM47-1.2	G1347F	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	G1347H	Pathogenic	0.513
NOTCH3	Q9UM47-1.2	G1347I	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G1347K	Neutral	0.498
NOTCH3	Q9UM47-1.2	G1347L	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G1347M	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	G1347N	Neutral	0.053
NOTCH3	Q9UM47-1.2	G1347P	Pathogenic	0.541
NOTCH3	Q9UM47-1.2	G1347Q	Pathogenic	0.517
NOTCH3	Q9UM47-1.2	G1347R	Neutral	0.486
NOTCH3	Q9UM47-1.2	G1347S	Neutral	0.057
NOTCH3	Q9UM47-1.2	G1347T	Pathogenic	0.537
NOTCH3	Q9UM47-1.2	G1347V	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	G1347W	Neutral	0.474
NOTCH3	Q9UM47-1.2	G1347Y	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	G1348A	Neutral	0.142
NOTCH3	Q9UM47-1.2	G1348C	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	G1348D	Neutral	0.408
NOTCH3	Q9UM47-1.2	G1348E	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	G1348F	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	G1348H	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	G1348I	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	G1348K	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	G1348L	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	G1348M	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	G1348N	Neutral	0.129
NOTCH3	Q9UM47-1.2	G1348P	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	G1348Q	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	G1348R	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	G1348S	Neutral	0.139
NOTCH3	Q9UM47-1.2	G1348T	Pathogenic	0.756
NOTCH3	Q9UM47-1.2	G1348V	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	G1348W	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	G1348Y	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	S1349A	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1349C	Neutral	0.076
NOTCH3	Q9UM47-1.2	S1349D	Neutral	0.017
NOTCH3	Q9UM47-1.2	S1349E	Neutral	0.016
NOTCH3	Q9UM47-1.2	S1349F	Neutral	0.238
NOTCH3	Q9UM47-1.2	S1349G	Neutral	0.017
NOTCH3	Q9UM47-1.2	S1349H	Neutral	0.067
NOTCH3	Q9UM47-1.2	S1349I	Neutral	0.246
NOTCH3	Q9UM47-1.2	S1349K	Neutral	0.015
NOTCH3	Q9UM47-1.2	S1349L	Neutral	0.246
NOTCH3	Q9UM47-1.2	S1349M	Neutral	0.067
NOTCH3	Q9UM47-1.2	S1349N	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1349P	Neutral	0.075
NOTCH3	Q9UM47-1.2	S1349Q	Neutral	0.016
NOTCH3	Q9UM47-1.2	S1349R	Neutral	0.061
NOTCH3	Q9UM47-1.2	S1349T	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1349V	Neutral	0.259
NOTCH3	Q9UM47-1.2	S1349W	Pathogenic	0.562
NOTCH3	Q9UM47-1.2	S1349Y	Neutral	0.233
NOTCH3	Q9UM47-1.2	C1350A	Neutral	0.471
NOTCH3	Q9UM47-1.2	C1350D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1350E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1350F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C1350G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1350H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1350I	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C1350K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1350L	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	C1350M	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	C1350N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1350P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1350Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1350R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1350S	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	C1350T	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C1350V	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	C1350W	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	C1350Y	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	R1351A	Neutral	0.009
NOTCH3	Q9UM47-1.2	R1351C	Neutral	0.172
NOTCH3	Q9UM47-1.2	R1351D	Neutral	0.044
NOTCH3	Q9UM47-1.2	R1351E	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1351F	Neutral	0.201
NOTCH3	Q9UM47-1.2	R1351G	Neutral	0.038
NOTCH3	Q9UM47-1.2	R1351H	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1351I	Neutral	0.195
NOTCH3	Q9UM47-1.2	R1351K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R1351L	Neutral	0.05
NOTCH3	Q9UM47-1.2	R1351M	Neutral	0.011
NOTCH3	Q9UM47-1.2	R1351N	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1351P	Neutral	0.044
NOTCH3	Q9UM47-1.2	R1351Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1351S	Neutral	0.009
NOTCH3	Q9UM47-1.2	R1351T	Neutral	0.01
NOTCH3	Q9UM47-1.2	R1351V	Neutral	0.183
NOTCH3	Q9UM47-1.2	R1351W	Neutral	0.201
NOTCH3	Q9UM47-1.2	R1351Y	Neutral	0.053
NOTCH3	Q9UM47-1.2	P1352A	Neutral	0.117
NOTCH3	Q9UM47-1.2	P1352C	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	P1352D	Neutral	0.128
NOTCH3	Q9UM47-1.2	P1352E	Neutral	0.12
NOTCH3	Q9UM47-1.2	P1352F	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	P1352G	Neutral	0.361
NOTCH3	Q9UM47-1.2	P1352H	Neutral	0.373
NOTCH3	Q9UM47-1.2	P1352I	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	P1352K	Neutral	0.11
NOTCH3	Q9UM47-1.2	P1352L	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	P1352M	Neutral	0.368
NOTCH3	Q9UM47-1.2	P1352N	Neutral	0.395
NOTCH3	Q9UM47-1.2	P1352Q	Neutral	0.118
NOTCH3	Q9UM47-1.2	P1352R	Neutral	0.349
NOTCH3	Q9UM47-1.2	P1352S	Neutral	0.12
NOTCH3	Q9UM47-1.2	P1352T	Neutral	0.126
NOTCH3	Q9UM47-1.2	P1352V	Neutral	0.385
NOTCH3	Q9UM47-1.2	P1352W	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	P1352Y	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	A1353C	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1353D	Neutral	0.014
NOTCH3	Q9UM47-1.2	A1353E	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1353F	Neutral	0.012
NOTCH3	Q9UM47-1.2	A1353G	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1353H	Neutral	0.013
NOTCH3	Q9UM47-1.2	A1353I	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1353K	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1353L	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1353M	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1353N	Neutral	0.014
NOTCH3	Q9UM47-1.2	A1353P	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1353Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1353R	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1353S	Neutral	0.0
NOTCH3	Q9UM47-1.2	A1353T	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1353V	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1353W	Neutral	0.047
NOTCH3	Q9UM47-1.2	A1353Y	Neutral	0.012
NOTCH3	Q9UM47-1.2	P1354A	Neutral	0.018
NOTCH3	Q9UM47-1.2	P1354C	Neutral	0.291
NOTCH3	Q9UM47-1.2	P1354D	Neutral	0.02
NOTCH3	Q9UM47-1.2	P1354E	Neutral	0.019
NOTCH3	Q9UM47-1.2	P1354F	Pathogenic	0.616
NOTCH3	Q9UM47-1.2	P1354G	Neutral	0.073
NOTCH3	Q9UM47-1.2	P1354H	Neutral	0.076
NOTCH3	Q9UM47-1.2	P1354I	Neutral	0.269
NOTCH3	Q9UM47-1.2	P1354K	Neutral	0.017
NOTCH3	Q9UM47-1.2	P1354L	Neutral	0.269
NOTCH3	Q9UM47-1.2	P1354M	Neutral	0.074
NOTCH3	Q9UM47-1.2	P1354N	Neutral	0.083
NOTCH3	Q9UM47-1.2	P1354Q	Neutral	0.018
NOTCH3	Q9UM47-1.2	P1354R	Neutral	0.069
NOTCH3	Q9UM47-1.2	P1354S	Neutral	0.019
NOTCH3	Q9UM47-1.2	P1354T	Neutral	0.02
NOTCH3	Q9UM47-1.2	P1354V	Neutral	0.08
NOTCH3	Q9UM47-1.2	P1354W	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	P1354Y	Neutral	0.255
NOTCH3	Q9UM47-1.2	L1355A	Neutral	0.005
NOTCH3	Q9UM47-1.2	L1355C	Neutral	0.006
NOTCH3	Q9UM47-1.2	L1355D	Neutral	0.36
NOTCH3	Q9UM47-1.2	L1355E	Neutral	0.117
NOTCH3	Q9UM47-1.2	L1355F	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1355G	Neutral	0.321
NOTCH3	Q9UM47-1.2	L1355H	Neutral	0.12
NOTCH3	Q9UM47-1.2	L1355I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1355K	Neutral	0.029
NOTCH3	Q9UM47-1.2	L1355M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1355N	Neutral	0.112
NOTCH3	Q9UM47-1.2	L1355P	Neutral	0.108
NOTCH3	Q9UM47-1.2	L1355Q	Neutral	0.029
NOTCH3	Q9UM47-1.2	L1355R	Neutral	0.027
NOTCH3	Q9UM47-1.2	L1355S	Neutral	0.025
NOTCH3	Q9UM47-1.2	L1355T	Neutral	0.006
NOTCH3	Q9UM47-1.2	L1355V	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1355W	Neutral	0.025
NOTCH3	Q9UM47-1.2	L1355Y	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1356C	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1356D	Neutral	0.104
NOTCH3	Q9UM47-1.2	A1356E	Neutral	0.023
NOTCH3	Q9UM47-1.2	A1356F	Neutral	0.09
NOTCH3	Q9UM47-1.2	A1356G	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1356H	Neutral	0.094
NOTCH3	Q9UM47-1.2	A1356I	Neutral	0.022
NOTCH3	Q9UM47-1.2	A1356K	Neutral	0.021
NOTCH3	Q9UM47-1.2	A1356L	Neutral	0.022
NOTCH3	Q9UM47-1.2	A1356M	Neutral	0.022
NOTCH3	Q9UM47-1.2	A1356N	Neutral	0.103
NOTCH3	Q9UM47-1.2	A1356P	Neutral	0.025
NOTCH3	Q9UM47-1.2	A1356Q	Neutral	0.023
NOTCH3	Q9UM47-1.2	A1356R	Neutral	0.02
NOTCH3	Q9UM47-1.2	A1356S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1356T	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1356V	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1356W	Neutral	0.288
NOTCH3	Q9UM47-1.2	A1356Y	Neutral	0.087
NOTCH3	Q9UM47-1.2	P1357A	Pathogenic	0.536
NOTCH3	Q9UM47-1.2	P1357C	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	P1357D	Pathogenic	0.559
NOTCH3	Q9UM47-1.2	P1357E	Pathogenic	0.542
NOTCH3	Q9UM47-1.2	P1357F	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	P1357G	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	P1357H	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	P1357I	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	P1357K	Pathogenic	0.518
NOTCH3	Q9UM47-1.2	P1357L	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	P1357M	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	P1357N	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	P1357Q	Pathogenic	0.536
NOTCH3	Q9UM47-1.2	P1357R	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	P1357S	Pathogenic	0.542
NOTCH3	Q9UM47-1.2	P1357T	Pathogenic	0.555
NOTCH3	Q9UM47-1.2	P1357V	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	P1357W	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	P1357Y	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	F1358A	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	F1358C	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	F1358D	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	F1358E	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	F1358G	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	F1358H	Pathogenic	0.583
NOTCH3	Q9UM47-1.2	F1358I	Neutral	0.236
NOTCH3	Q9UM47-1.2	F1358K	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	F1358L	Neutral	0.237
NOTCH3	Q9UM47-1.2	F1358M	Neutral	0.237
NOTCH3	Q9UM47-1.2	F1358N	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	F1358P	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	F1358Q	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	F1358R	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	F1358S	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	F1358T	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	F1358V	Pathogenic	0.568
NOTCH3	Q9UM47-1.2	F1358W	Neutral	0.06
NOTCH3	Q9UM47-1.2	F1358Y	Neutral	0.003
NOTCH3	Q9UM47-1.2	F1359A	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	F1359C	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	F1359D	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	F1359E	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	F1359G	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	F1359H	Neutral	0.44
NOTCH3	Q9UM47-1.2	F1359I	Neutral	0.148
NOTCH3	Q9UM47-1.2	F1359K	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	F1359L	Neutral	0.148
NOTCH3	Q9UM47-1.2	F1359M	Neutral	0.149
NOTCH3	Q9UM47-1.2	F1359N	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	F1359P	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	F1359Q	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	F1359R	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	F1359S	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	F1359T	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	F1359V	Neutral	0.425
NOTCH3	Q9UM47-1.2	F1359W	Neutral	0.035
NOTCH3	Q9UM47-1.2	F1359Y	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1360A	Neutral	0.088
NOTCH3	Q9UM47-1.2	R1360C	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	R1360D	Neutral	0.323
NOTCH3	Q9UM47-1.2	R1360E	Neutral	0.024
NOTCH3	Q9UM47-1.2	R1360F	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	R1360G	Neutral	0.289
NOTCH3	Q9UM47-1.2	R1360H	Neutral	0.025
NOTCH3	Q9UM47-1.2	R1360I	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	R1360K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1360L	Neutral	0.356
NOTCH3	Q9UM47-1.2	R1360M	Neutral	0.108
NOTCH3	Q9UM47-1.2	R1360N	Neutral	0.023
NOTCH3	Q9UM47-1.2	R1360P	Neutral	0.324
NOTCH3	Q9UM47-1.2	R1360Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	R1360S	Neutral	0.089
NOTCH3	Q9UM47-1.2	R1360T	Neutral	0.096
NOTCH3	Q9UM47-1.2	R1360V	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	R1360W	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	R1360Y	Neutral	0.369
NOTCH3	Q9UM47-1.2	C1361A	Neutral	0.46
NOTCH3	Q9UM47-1.2	C1361D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1361E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1361F	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	C1361G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1361H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1361I	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	C1361K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1361L	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	C1361M	Pathogenic	0.782
NOTCH3	Q9UM47-1.2	C1361N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1361P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1361Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1361R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1361S	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	C1361T	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C1361V	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	C1361W	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	C1361Y	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	A1362C	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1362D	Neutral	0.014
NOTCH3	Q9UM47-1.2	A1362E	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1362F	Neutral	0.012
NOTCH3	Q9UM47-1.2	A1362G	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1362H	Neutral	0.012
NOTCH3	Q9UM47-1.2	A1362I	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1362K	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1362L	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1362M	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1362N	Neutral	0.014
NOTCH3	Q9UM47-1.2	A1362P	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1362Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1362R	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1362S	Neutral	0.0
NOTCH3	Q9UM47-1.2	A1362T	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1362V	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1362W	Neutral	0.047
NOTCH3	Q9UM47-1.2	A1362Y	Neutral	0.011
NOTCH3	Q9UM47-1.2	C1363A	Neutral	0.469
NOTCH3	Q9UM47-1.2	C1363D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1363E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1363F	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C1363G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1363H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1363I	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	C1363K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1363L	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	C1363M	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	C1363N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1363P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1363Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1363R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1363S	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C1363T	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1363V	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	C1363W	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	C1363Y	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	A1364C	Neutral	0.008
NOTCH3	Q9UM47-1.2	A1364D	Neutral	0.136
NOTCH3	Q9UM47-1.2	A1364E	Neutral	0.031
NOTCH3	Q9UM47-1.2	A1364F	Neutral	0.117
NOTCH3	Q9UM47-1.2	A1364G	Neutral	0.008
NOTCH3	Q9UM47-1.2	A1364H	Neutral	0.123
NOTCH3	Q9UM47-1.2	A1364I	Neutral	0.03
NOTCH3	Q9UM47-1.2	A1364K	Neutral	0.028
NOTCH3	Q9UM47-1.2	A1364L	Neutral	0.03
NOTCH3	Q9UM47-1.2	A1364M	Neutral	0.029
NOTCH3	Q9UM47-1.2	A1364N	Neutral	0.133
NOTCH3	Q9UM47-1.2	A1364P	Neutral	0.033
NOTCH3	Q9UM47-1.2	A1364Q	Neutral	0.03
NOTCH3	Q9UM47-1.2	A1364R	Neutral	0.027
NOTCH3	Q9UM47-1.2	A1364S	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1364T	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1364V	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1364W	Neutral	0.353
NOTCH3	Q9UM47-1.2	A1364Y	Neutral	0.114
NOTCH3	Q9UM47-1.2	Q1365A	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1365C	Neutral	0.013
NOTCH3	Q9UM47-1.2	Q1365D	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1365E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1365F	Neutral	0.013
NOTCH3	Q9UM47-1.2	Q1365G	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q1365H	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1365I	Neutral	0.014
NOTCH3	Q9UM47-1.2	Q1365K	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1365L	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q1365M	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1365N	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1365P	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1365R	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1365S	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1365T	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1365V	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q1365W	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q1365Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	G1366A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1366C	Neutral	0.154
NOTCH3	Q9UM47-1.2	G1366D	Neutral	0.009
NOTCH3	Q9UM47-1.2	G1366E	Neutral	0.035
NOTCH3	Q9UM47-1.2	G1366F	Neutral	0.131
NOTCH3	Q9UM47-1.2	G1366H	Neutral	0.034
NOTCH3	Q9UM47-1.2	G1366I	Neutral	0.418
NOTCH3	Q9UM47-1.2	G1366K	Neutral	0.032
NOTCH3	Q9UM47-1.2	G1366L	Neutral	0.418
NOTCH3	Q9UM47-1.2	G1366M	Neutral	0.136
NOTCH3	Q9UM47-1.2	G1366N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1366P	Neutral	0.038
NOTCH3	Q9UM47-1.2	G1366Q	Neutral	0.034
NOTCH3	Q9UM47-1.2	G1366R	Neutral	0.03
NOTCH3	Q9UM47-1.2	G1366S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1366T	Neutral	0.037
NOTCH3	Q9UM47-1.2	G1366V	Neutral	0.145
NOTCH3	Q9UM47-1.2	G1366W	Neutral	0.029
NOTCH3	Q9UM47-1.2	G1366Y	Neutral	0.128
NOTCH3	Q9UM47-1.2	W1367A	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	W1367C	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	W1367D	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	W1367E	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	W1367F	Neutral	0.113
NOTCH3	Q9UM47-1.2	W1367G	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	W1367H	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	W1367I	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	W1367K	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	W1367L	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	W1367M	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	W1367N	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	W1367P	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	W1367Q	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	W1367R	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	W1367S	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	W1367T	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	W1367V	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	W1367Y	Neutral	0.028
NOTCH3	Q9UM47-1.2	T1368A	Neutral	0.002
NOTCH3	Q9UM47-1.2	T1368C	Neutral	0.009
NOTCH3	Q9UM47-1.2	T1368D	Neutral	0.009
NOTCH3	Q9UM47-1.2	T1368E	Neutral	0.009
NOTCH3	Q9UM47-1.2	T1368F	Neutral	0.035
NOTCH3	Q9UM47-1.2	T1368G	Neutral	0.035
NOTCH3	Q9UM47-1.2	T1368H	Neutral	0.037
NOTCH3	Q9UM47-1.2	T1368I	Neutral	0.008
NOTCH3	Q9UM47-1.2	T1368K	Neutral	0.008
NOTCH3	Q9UM47-1.2	T1368L	Neutral	0.008
NOTCH3	Q9UM47-1.2	T1368M	Neutral	0.008
NOTCH3	Q9UM47-1.2	T1368N	Neutral	0.002
NOTCH3	Q9UM47-1.2	T1368P	Neutral	0.009
NOTCH3	Q9UM47-1.2	T1368Q	Neutral	0.009
NOTCH3	Q9UM47-1.2	T1368R	Neutral	0.008
NOTCH3	Q9UM47-1.2	T1368S	Neutral	0.0
NOTCH3	Q9UM47-1.2	T1368V	Neutral	0.002
NOTCH3	Q9UM47-1.2	T1368W	Neutral	0.032
NOTCH3	Q9UM47-1.2	T1368Y	Neutral	0.034
NOTCH3	Q9UM47-1.2	G1369A	Neutral	0.217
NOTCH3	Q9UM47-1.2	G1369C	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G1369D	Pathogenic	0.536
NOTCH3	Q9UM47-1.2	G1369E	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	G1369F	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	G1369H	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	G1369I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1369K	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	G1369L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1369M	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G1369N	Neutral	0.199
NOTCH3	Q9UM47-1.2	G1369P	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	G1369Q	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	G1369R	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	G1369S	Neutral	0.213
NOTCH3	Q9UM47-1.2	G1369T	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	G1369V	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G1369W	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	G1369Y	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	P1370A	Neutral	0.01
NOTCH3	Q9UM47-1.2	P1370C	Neutral	0.18
NOTCH3	Q9UM47-1.2	P1370D	Neutral	0.011
NOTCH3	Q9UM47-1.2	P1370E	Neutral	0.01
NOTCH3	Q9UM47-1.2	P1370F	Neutral	0.462
NOTCH3	Q9UM47-1.2	P1370G	Neutral	0.04
NOTCH3	Q9UM47-1.2	P1370H	Neutral	0.042
NOTCH3	Q9UM47-1.2	P1370I	Neutral	0.164
NOTCH3	Q9UM47-1.2	P1370K	Neutral	0.009
NOTCH3	Q9UM47-1.2	P1370L	Neutral	0.164
NOTCH3	Q9UM47-1.2	P1370M	Neutral	0.041
NOTCH3	Q9UM47-1.2	P1370N	Neutral	0.046
NOTCH3	Q9UM47-1.2	P1370Q	Neutral	0.01
NOTCH3	Q9UM47-1.2	P1370R	Neutral	0.038
NOTCH3	Q9UM47-1.2	P1370S	Neutral	0.01
NOTCH3	Q9UM47-1.2	P1370T	Neutral	0.011
NOTCH3	Q9UM47-1.2	P1370V	Neutral	0.044
NOTCH3	Q9UM47-1.2	P1370W	Neutral	0.436
NOTCH3	Q9UM47-1.2	P1370Y	Neutral	0.155
NOTCH3	Q9UM47-1.2	R1371A	Neutral	0.093
NOTCH3	Q9UM47-1.2	R1371C	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	R1371D	Neutral	0.335
NOTCH3	Q9UM47-1.2	R1371E	Neutral	0.025
NOTCH3	Q9UM47-1.2	R1371F	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	R1371G	Neutral	0.301
NOTCH3	Q9UM47-1.2	R1371H	Neutral	0.027
NOTCH3	Q9UM47-1.2	R1371I	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	R1371K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1371L	Neutral	0.369
NOTCH3	Q9UM47-1.2	R1371M	Neutral	0.113
NOTCH3	Q9UM47-1.2	R1371N	Neutral	0.024
NOTCH3	Q9UM47-1.2	R1371P	Neutral	0.337
NOTCH3	Q9UM47-1.2	R1371Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	R1371S	Neutral	0.094
NOTCH3	Q9UM47-1.2	R1371T	Neutral	0.101
NOTCH3	Q9UM47-1.2	R1371V	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	R1371W	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	R1371Y	Neutral	0.383
NOTCH3	Q9UM47-1.2	C1372A	Neutral	0.455
NOTCH3	Q9UM47-1.2	C1372D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1372E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1372F	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	C1372G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1372H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1372I	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	C1372K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1372L	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	C1372M	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	C1372N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1372P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1372Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1372R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	C1372S	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	C1372T	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	C1372V	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	C1372W	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	C1372Y	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	E1373A	Neutral	0.298
NOTCH3	Q9UM47-1.2	E1373C	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	E1373D	Neutral	0.005
NOTCH3	Q9UM47-1.2	E1373F	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	E1373G	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	E1373H	Neutral	0.096
NOTCH3	Q9UM47-1.2	E1373I	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	E1373K	Neutral	0.021
NOTCH3	Q9UM47-1.2	E1373L	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	E1373M	Pathogenic	0.684
NOTCH3	Q9UM47-1.2	E1373N	Neutral	0.094
NOTCH3	Q9UM47-1.2	E1373P	Neutral	0.318
NOTCH3	Q9UM47-1.2	E1373Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	E1373R	Neutral	0.086
NOTCH3	Q9UM47-1.2	E1373S	Neutral	0.087
NOTCH3	Q9UM47-1.2	E1373T	Neutral	0.319
NOTCH3	Q9UM47-1.2	E1373V	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	E1373W	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	E1373Y	Pathogenic	0.669
NOTCH3	Q9UM47-1.2	A1374C	Neutral	0.0
NOTCH3	Q9UM47-1.2	A1374D	Neutral	0.009
NOTCH3	Q9UM47-1.2	A1374E	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1374F	Neutral	0.008
NOTCH3	Q9UM47-1.2	A1374G	Neutral	0.0
NOTCH3	Q9UM47-1.2	A1374H	Neutral	0.008
NOTCH3	Q9UM47-1.2	A1374I	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1374K	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1374L	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1374M	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1374N	Neutral	0.009
NOTCH3	Q9UM47-1.2	A1374P	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1374Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1374R	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1374S	Neutral	0.0
NOTCH3	Q9UM47-1.2	A1374T	Neutral	0.0
NOTCH3	Q9UM47-1.2	A1374V	Neutral	0.0
NOTCH3	Q9UM47-1.2	A1374W	Neutral	0.032
NOTCH3	Q9UM47-1.2	A1374Y	Neutral	0.008
NOTCH3	Q9UM47-1.2	P1375A	Neutral	0.016
NOTCH3	Q9UM47-1.2	P1375C	Neutral	0.271
NOTCH3	Q9UM47-1.2	P1375D	Neutral	0.018
NOTCH3	Q9UM47-1.2	P1375E	Neutral	0.017
NOTCH3	Q9UM47-1.2	P1375F	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	P1375G	Neutral	0.066
NOTCH3	Q9UM47-1.2	P1375H	Neutral	0.07
NOTCH3	Q9UM47-1.2	P1375I	Neutral	0.25
NOTCH3	Q9UM47-1.2	P1375K	Neutral	0.015
NOTCH3	Q9UM47-1.2	P1375L	Neutral	0.25
NOTCH3	Q9UM47-1.2	P1375M	Neutral	0.068
NOTCH3	Q9UM47-1.2	P1375N	Neutral	0.076
NOTCH3	Q9UM47-1.2	P1375Q	Neutral	0.016
NOTCH3	Q9UM47-1.2	P1375R	Neutral	0.063
NOTCH3	Q9UM47-1.2	P1375S	Neutral	0.017
NOTCH3	Q9UM47-1.2	P1375T	Neutral	0.018
NOTCH3	Q9UM47-1.2	P1375V	Neutral	0.073
NOTCH3	Q9UM47-1.2	P1375W	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	P1375Y	Neutral	0.237
NOTCH3	Q9UM47-1.2	A1376C	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1376D	Neutral	0.1
NOTCH3	Q9UM47-1.2	A1376E	Neutral	0.022
NOTCH3	Q9UM47-1.2	A1376F	Neutral	0.086
NOTCH3	Q9UM47-1.2	A1376G	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1376H	Neutral	0.09
NOTCH3	Q9UM47-1.2	A1376I	Neutral	0.021
NOTCH3	Q9UM47-1.2	A1376K	Neutral	0.02
NOTCH3	Q9UM47-1.2	A1376L	Neutral	0.021
NOTCH3	Q9UM47-1.2	A1376M	Neutral	0.021
NOTCH3	Q9UM47-1.2	A1376N	Neutral	0.098
NOTCH3	Q9UM47-1.2	A1376P	Neutral	0.024
NOTCH3	Q9UM47-1.2	A1376Q	Neutral	0.022
NOTCH3	Q9UM47-1.2	A1376R	Neutral	0.019
NOTCH3	Q9UM47-1.2	A1376S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1376T	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1376V	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1376W	Neutral	0.278
NOTCH3	Q9UM47-1.2	A1376Y	Neutral	0.083
NOTCH3	Q9UM47-1.2	A1377C	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1377D	Neutral	0.019
NOTCH3	Q9UM47-1.2	A1377E	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1377F	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1377G	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1377H	Neutral	0.017
NOTCH3	Q9UM47-1.2	A1377I	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1377K	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1377L	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1377M	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1377N	Neutral	0.019
NOTCH3	Q9UM47-1.2	A1377P	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1377Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1377R	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1377S	Neutral	0.0
NOTCH3	Q9UM47-1.2	A1377T	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1377V	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1377W	Neutral	0.063
NOTCH3	Q9UM47-1.2	A1377Y	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1378C	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1378D	Neutral	0.027
NOTCH3	Q9UM47-1.2	A1378E	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1378F	Neutral	0.023
NOTCH3	Q9UM47-1.2	A1378G	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1378H	Neutral	0.024
NOTCH3	Q9UM47-1.2	A1378I	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1378K	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1378L	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1378M	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1378N	Neutral	0.026
NOTCH3	Q9UM47-1.2	A1378P	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1378Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1378R	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1378S	Neutral	0.0
NOTCH3	Q9UM47-1.2	A1378T	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1378V	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1378W	Neutral	0.088
NOTCH3	Q9UM47-1.2	A1378Y	Neutral	0.022
NOTCH3	Q9UM47-1.2	P1379A	Neutral	0.066
NOTCH3	Q9UM47-1.2	P1379C	Pathogenic	0.61
NOTCH3	Q9UM47-1.2	P1379D	Neutral	0.071
NOTCH3	Q9UM47-1.2	P1379E	Neutral	0.067
NOTCH3	Q9UM47-1.2	P1379F	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	P1379G	Neutral	0.229
NOTCH3	Q9UM47-1.2	P1379H	Neutral	0.239
NOTCH3	Q9UM47-1.2	P1379I	Pathogenic	0.583
NOTCH3	Q9UM47-1.2	P1379K	Neutral	0.061
NOTCH3	Q9UM47-1.2	P1379L	Pathogenic	0.583
NOTCH3	Q9UM47-1.2	P1379M	Neutral	0.234
NOTCH3	Q9UM47-1.2	P1379N	Neutral	0.256
NOTCH3	Q9UM47-1.2	P1379Q	Neutral	0.066
NOTCH3	Q9UM47-1.2	P1379R	Neutral	0.22
NOTCH3	Q9UM47-1.2	P1379S	Neutral	0.067
NOTCH3	Q9UM47-1.2	P1379T	Neutral	0.07
NOTCH3	Q9UM47-1.2	P1379V	Neutral	0.248
NOTCH3	Q9UM47-1.2	P1379W	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	P1379Y	Pathogenic	0.566
NOTCH3	Q9UM47-1.2	E1380A	Neutral	0.04
NOTCH3	Q9UM47-1.2	E1380C	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	E1380D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1380F	Neutral	0.481
NOTCH3	Q9UM47-1.2	E1380G	Neutral	0.149
NOTCH3	Q9UM47-1.2	E1380H	Neutral	0.01
NOTCH3	Q9UM47-1.2	E1380I	Neutral	0.492
NOTCH3	Q9UM47-1.2	E1380K	Neutral	0.002
NOTCH3	Q9UM47-1.2	E1380L	Neutral	0.491
NOTCH3	Q9UM47-1.2	E1380M	Neutral	0.175
NOTCH3	Q9UM47-1.2	E1380N	Neutral	0.01
NOTCH3	Q9UM47-1.2	E1380P	Neutral	0.044
NOTCH3	Q9UM47-1.2	E1380Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1380R	Neutral	0.009
NOTCH3	Q9UM47-1.2	E1380S	Neutral	0.009
NOTCH3	Q9UM47-1.2	E1380T	Neutral	0.044
NOTCH3	Q9UM47-1.2	E1380V	Neutral	0.181
NOTCH3	Q9UM47-1.2	E1380W	Neutral	0.455
NOTCH3	Q9UM47-1.2	E1380Y	Neutral	0.165
NOTCH3	Q9UM47-1.2	V1381A	Neutral	0.003
NOTCH3	Q9UM47-1.2	V1381C	Neutral	0.014
NOTCH3	Q9UM47-1.2	V1381D	Neutral	0.235
NOTCH3	Q9UM47-1.2	V1381E	Neutral	0.065
NOTCH3	Q9UM47-1.2	V1381F	Neutral	0.014
NOTCH3	Q9UM47-1.2	V1381G	Neutral	0.205
NOTCH3	Q9UM47-1.2	V1381H	Neutral	0.234
NOTCH3	Q9UM47-1.2	V1381I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V1381K	Neutral	0.06
NOTCH3	Q9UM47-1.2	V1381L	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1381M	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1381N	Neutral	0.238
NOTCH3	Q9UM47-1.2	V1381P	Neutral	0.062
NOTCH3	Q9UM47-1.2	V1381Q	Neutral	0.064
NOTCH3	Q9UM47-1.2	V1381R	Neutral	0.215
NOTCH3	Q9UM47-1.2	V1381S	Neutral	0.059
NOTCH3	Q9UM47-1.2	V1381T	Neutral	0.003
NOTCH3	Q9UM47-1.2	V1381W	Neutral	0.204
NOTCH3	Q9UM47-1.2	V1381Y	Neutral	0.013
NOTCH3	Q9UM47-1.2	S1382A	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1382C	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1382D	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1382E	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1382F	Neutral	0.012
NOTCH3	Q9UM47-1.2	S1382G	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1382H	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1382I	Neutral	0.013
NOTCH3	Q9UM47-1.2	S1382K	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1382L	Neutral	0.013
NOTCH3	Q9UM47-1.2	S1382M	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1382N	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1382P	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1382Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1382R	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1382T	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1382V	Neutral	0.013
NOTCH3	Q9UM47-1.2	S1382W	Neutral	0.048
NOTCH3	Q9UM47-1.2	S1382Y	Neutral	0.012
NOTCH3	Q9UM47-1.2	E1383A	Neutral	0.032
NOTCH3	Q9UM47-1.2	E1383C	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	E1383D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1383F	Neutral	0.425
NOTCH3	Q9UM47-1.2	E1383G	Neutral	0.123
NOTCH3	Q9UM47-1.2	E1383H	Neutral	0.008
NOTCH3	Q9UM47-1.2	E1383I	Neutral	0.435
NOTCH3	Q9UM47-1.2	E1383K	Neutral	0.002
NOTCH3	Q9UM47-1.2	E1383L	Neutral	0.435
NOTCH3	Q9UM47-1.2	E1383M	Neutral	0.144
NOTCH3	Q9UM47-1.2	E1383N	Neutral	0.008
NOTCH3	Q9UM47-1.2	E1383P	Neutral	0.035
NOTCH3	Q9UM47-1.2	E1383Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1383R	Neutral	0.007
NOTCH3	Q9UM47-1.2	E1383S	Neutral	0.007
NOTCH3	Q9UM47-1.2	E1383T	Neutral	0.035
NOTCH3	Q9UM47-1.2	E1383V	Neutral	0.15
NOTCH3	Q9UM47-1.2	E1383W	Neutral	0.4
NOTCH3	Q9UM47-1.2	E1383Y	Neutral	0.136
NOTCH3	Q9UM47-1.2	E1384A	Neutral	0.202
NOTCH3	Q9UM47-1.2	E1384C	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	E1384D	Neutral	0.003
NOTCH3	Q9UM47-1.2	E1384F	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	E1384G	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	E1384H	Neutral	0.059
NOTCH3	Q9UM47-1.2	E1384I	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	E1384K	Neutral	0.013
NOTCH3	Q9UM47-1.2	E1384L	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	E1384M	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	E1384N	Neutral	0.058
NOTCH3	Q9UM47-1.2	E1384P	Neutral	0.217
NOTCH3	Q9UM47-1.2	E1384Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	E1384R	Neutral	0.053
NOTCH3	Q9UM47-1.2	E1384S	Neutral	0.054
NOTCH3	Q9UM47-1.2	E1384T	Neutral	0.219
NOTCH3	Q9UM47-1.2	E1384V	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	E1384W	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	E1384Y	Pathogenic	0.546
NOTCH3	Q9UM47-1.2	P1385A	Neutral	0.015
NOTCH3	Q9UM47-1.2	P1385C	Neutral	0.256
NOTCH3	Q9UM47-1.2	P1385D	Neutral	0.017
NOTCH3	Q9UM47-1.2	P1385E	Neutral	0.016
NOTCH3	Q9UM47-1.2	P1385F	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	P1385G	Neutral	0.061
NOTCH3	Q9UM47-1.2	P1385H	Neutral	0.065
NOTCH3	Q9UM47-1.2	P1385I	Neutral	0.235
NOTCH3	Q9UM47-1.2	P1385K	Neutral	0.014
NOTCH3	Q9UM47-1.2	P1385L	Neutral	0.235
NOTCH3	Q9UM47-1.2	P1385M	Neutral	0.063
NOTCH3	Q9UM47-1.2	P1385N	Neutral	0.07
NOTCH3	Q9UM47-1.2	P1385Q	Neutral	0.015
NOTCH3	Q9UM47-1.2	P1385R	Neutral	0.058
NOTCH3	Q9UM47-1.2	P1385S	Neutral	0.016
NOTCH3	Q9UM47-1.2	P1385T	Neutral	0.016
NOTCH3	Q9UM47-1.2	P1385V	Neutral	0.068
NOTCH3	Q9UM47-1.2	P1385W	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	P1385Y	Neutral	0.223
NOTCH3	Q9UM47-1.2	R1386A	Neutral	0.008
NOTCH3	Q9UM47-1.2	R1386C	Neutral	0.156
NOTCH3	Q9UM47-1.2	R1386D	Neutral	0.039
NOTCH3	Q9UM47-1.2	R1386E	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1386F	Neutral	0.184
NOTCH3	Q9UM47-1.2	R1386G	Neutral	0.034
NOTCH3	Q9UM47-1.2	R1386H	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1386I	Neutral	0.178
NOTCH3	Q9UM47-1.2	R1386K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R1386L	Neutral	0.045
NOTCH3	Q9UM47-1.2	R1386M	Neutral	0.01
NOTCH3	Q9UM47-1.2	R1386N	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1386P	Neutral	0.04
NOTCH3	Q9UM47-1.2	R1386Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	R1386S	Neutral	0.008
NOTCH3	Q9UM47-1.2	R1386T	Neutral	0.009
NOTCH3	Q9UM47-1.2	R1386V	Neutral	0.166
NOTCH3	Q9UM47-1.2	R1386W	Neutral	0.183
NOTCH3	Q9UM47-1.2	R1386Y	Neutral	0.048
NOTCH3	Q9UM47-1.2	C1387A	Neutral	0.461
NOTCH3	Q9UM47-1.2	C1387D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1387E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1387F	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	C1387G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1387H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1387I	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	C1387K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1387L	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	C1387M	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	C1387N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1387P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1387Q	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1387R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	C1387S	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	C1387T	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C1387V	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	C1387W	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	C1387Y	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	P1388A	Neutral	0.03
NOTCH3	Q9UM47-1.2	P1388C	Neutral	0.411
NOTCH3	Q9UM47-1.2	P1388D	Neutral	0.033
NOTCH3	Q9UM47-1.2	P1388E	Neutral	0.031
NOTCH3	Q9UM47-1.2	P1388F	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	P1388G	Neutral	0.117
NOTCH3	Q9UM47-1.2	P1388H	Neutral	0.123
NOTCH3	Q9UM47-1.2	P1388I	Neutral	0.385
NOTCH3	Q9UM47-1.2	P1388K	Neutral	0.028
NOTCH3	Q9UM47-1.2	P1388L	Neutral	0.384
NOTCH3	Q9UM47-1.2	P1388M	Neutral	0.12
NOTCH3	Q9UM47-1.2	P1388N	Neutral	0.133
NOTCH3	Q9UM47-1.2	P1388Q	Neutral	0.03
NOTCH3	Q9UM47-1.2	P1388R	Neutral	0.112
NOTCH3	Q9UM47-1.2	P1388S	Neutral	0.031
NOTCH3	Q9UM47-1.2	P1388T	Neutral	0.033
NOTCH3	Q9UM47-1.2	P1388V	Neutral	0.128
NOTCH3	Q9UM47-1.2	P1388W	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	P1388Y	Neutral	0.368
NOTCH3	Q9UM47-1.2	R1389A	Neutral	0.008
NOTCH3	Q9UM47-1.2	R1389C	Neutral	0.161
NOTCH3	Q9UM47-1.2	R1389D	Neutral	0.041
NOTCH3	Q9UM47-1.2	R1389E	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1389F	Neutral	0.189
NOTCH3	Q9UM47-1.2	R1389G	Neutral	0.035
NOTCH3	Q9UM47-1.2	R1389H	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1389I	Neutral	0.182
NOTCH3	Q9UM47-1.2	R1389K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R1389L	Neutral	0.047
NOTCH3	Q9UM47-1.2	R1389M	Neutral	0.011
NOTCH3	Q9UM47-1.2	R1389N	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1389P	Neutral	0.041
NOTCH3	Q9UM47-1.2	R1389Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	R1389S	Neutral	0.009
NOTCH3	Q9UM47-1.2	R1389T	Neutral	0.009
NOTCH3	Q9UM47-1.2	R1389V	Neutral	0.171
NOTCH3	Q9UM47-1.2	R1389W	Neutral	0.188
NOTCH3	Q9UM47-1.2	R1389Y	Neutral	0.049
NOTCH3	Q9UM47-1.2	A1390C	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1390D	Neutral	0.101
NOTCH3	Q9UM47-1.2	A1390E	Neutral	0.023
NOTCH3	Q9UM47-1.2	A1390F	Neutral	0.087
NOTCH3	Q9UM47-1.2	A1390G	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1390H	Neutral	0.091
NOTCH3	Q9UM47-1.2	A1390I	Neutral	0.021
NOTCH3	Q9UM47-1.2	A1390K	Neutral	0.02
NOTCH3	Q9UM47-1.2	A1390L	Neutral	0.021
NOTCH3	Q9UM47-1.2	A1390M	Neutral	0.021
NOTCH3	Q9UM47-1.2	A1390N	Neutral	0.099
NOTCH3	Q9UM47-1.2	A1390P	Neutral	0.024
NOTCH3	Q9UM47-1.2	A1390Q	Neutral	0.022
NOTCH3	Q9UM47-1.2	A1390R	Neutral	0.019
NOTCH3	Q9UM47-1.2	A1390S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1390T	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1390V	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1390W	Neutral	0.281
NOTCH3	Q9UM47-1.2	A1390Y	Neutral	0.085
NOTCH3	Q9UM47-1.2	A1391C	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1391D	Neutral	0.035
NOTCH3	Q9UM47-1.2	A1391E	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1391F	Neutral	0.03
NOTCH3	Q9UM47-1.2	A1391G	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1391H	Neutral	0.032
NOTCH3	Q9UM47-1.2	A1391I	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1391K	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1391L	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1391M	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1391N	Neutral	0.034
NOTCH3	Q9UM47-1.2	A1391P	Neutral	0.008
NOTCH3	Q9UM47-1.2	A1391Q	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1391R	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1391S	Neutral	0.0
NOTCH3	Q9UM47-1.2	A1391T	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1391V	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1391W	Neutral	0.112
NOTCH3	Q9UM47-1.2	A1391Y	Neutral	0.029
NOTCH3	Q9UM47-1.2	C1392A	Neutral	0.479
NOTCH3	Q9UM47-1.2	C1392D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1392E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	C1392F	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	C1392G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1392H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1392I	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	C1392K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1392L	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	C1392M	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	C1392N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1392P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1392Q	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1392R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1392S	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C1392T	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C1392V	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C1392W	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	C1392Y	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	Q1393A	Neutral	0.022
NOTCH3	Q9UM47-1.2	Q1393C	Neutral	0.333
NOTCH3	Q9UM47-1.2	Q1393D	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q1393E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1393F	Neutral	0.34
NOTCH3	Q9UM47-1.2	Q1393G	Neutral	0.086
NOTCH3	Q9UM47-1.2	Q1393H	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q1393I	Neutral	0.35
NOTCH3	Q9UM47-1.2	Q1393K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1393L	Neutral	0.106
NOTCH3	Q9UM47-1.2	Q1393M	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q1393N	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q1393P	Neutral	0.024
NOTCH3	Q9UM47-1.2	Q1393R	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1393S	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q1393T	Neutral	0.024
NOTCH3	Q9UM47-1.2	Q1393V	Neutral	0.106
NOTCH3	Q9UM47-1.2	Q1393W	Neutral	0.093
NOTCH3	Q9UM47-1.2	Q1393Y	Neutral	0.024
NOTCH3	Q9UM47-1.2	A1394C	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1394D	Neutral	0.068
NOTCH3	Q9UM47-1.2	A1394E	Neutral	0.015
NOTCH3	Q9UM47-1.2	A1394F	Neutral	0.058
NOTCH3	Q9UM47-1.2	A1394G	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1394H	Neutral	0.061
NOTCH3	Q9UM47-1.2	A1394I	Neutral	0.014
NOTCH3	Q9UM47-1.2	A1394K	Neutral	0.013
NOTCH3	Q9UM47-1.2	A1394L	Neutral	0.014
NOTCH3	Q9UM47-1.2	A1394M	Neutral	0.014
NOTCH3	Q9UM47-1.2	A1394N	Neutral	0.066
NOTCH3	Q9UM47-1.2	A1394P	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1394Q	Neutral	0.014
NOTCH3	Q9UM47-1.2	A1394R	Neutral	0.013
NOTCH3	Q9UM47-1.2	A1394S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1394T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1394V	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1394W	Neutral	0.201
NOTCH3	Q9UM47-1.2	A1394Y	Neutral	0.056
NOTCH3	Q9UM47-1.2	K1395A	Neutral	0.395
NOTCH3	Q9UM47-1.2	K1395C	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	K1395D	Neutral	0.416
NOTCH3	Q9UM47-1.2	K1395E	Neutral	0.036
NOTCH3	Q9UM47-1.2	K1395F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	K1395G	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	K1395H	Neutral	0.443
NOTCH3	Q9UM47-1.2	K1395I	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	K1395L	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	K1395M	Neutral	0.451
NOTCH3	Q9UM47-1.2	K1395N	Neutral	0.138
NOTCH3	Q9UM47-1.2	K1395P	Neutral	0.418
NOTCH3	Q9UM47-1.2	K1395Q	Neutral	0.036
NOTCH3	Q9UM47-1.2	K1395R	Neutral	0.008
NOTCH3	Q9UM47-1.2	K1395S	Neutral	0.128
NOTCH3	Q9UM47-1.2	K1395T	Neutral	0.42
NOTCH3	Q9UM47-1.2	K1395V	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	K1395W	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	K1395Y	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	R1396A	Neutral	0.027
NOTCH3	Q9UM47-1.2	R1396C	Neutral	0.384
NOTCH3	Q9UM47-1.2	R1396D	Neutral	0.121
NOTCH3	Q9UM47-1.2	R1396E	Neutral	0.007
NOTCH3	Q9UM47-1.2	R1396F	Neutral	0.431
NOTCH3	Q9UM47-1.2	R1396G	Neutral	0.105
NOTCH3	Q9UM47-1.2	R1396H	Neutral	0.007
NOTCH3	Q9UM47-1.2	R1396I	Neutral	0.421
NOTCH3	Q9UM47-1.2	R1396K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R1396L	Neutral	0.138
NOTCH3	Q9UM47-1.2	R1396M	Neutral	0.034
NOTCH3	Q9UM47-1.2	R1396N	Neutral	0.007
NOTCH3	Q9UM47-1.2	R1396P	Neutral	0.122
NOTCH3	Q9UM47-1.2	R1396Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1396S	Neutral	0.028
NOTCH3	Q9UM47-1.2	R1396T	Neutral	0.03
NOTCH3	Q9UM47-1.2	R1396V	Neutral	0.402
NOTCH3	Q9UM47-1.2	R1396W	Neutral	0.431
NOTCH3	Q9UM47-1.2	R1396Y	Neutral	0.145
NOTCH3	Q9UM47-1.2	G1397A	Neutral	0.031
NOTCH3	Q9UM47-1.2	G1397C	Pathogenic	0.736
NOTCH3	Q9UM47-1.2	G1397D	Neutral	0.116
NOTCH3	Q9UM47-1.2	G1397E	Neutral	0.359
NOTCH3	Q9UM47-1.2	G1397F	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	G1397H	Neutral	0.35
NOTCH3	Q9UM47-1.2	G1397I	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	G1397K	Neutral	0.336
NOTCH3	Q9UM47-1.2	G1397L	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	G1397M	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	G1397N	Neutral	0.028
NOTCH3	Q9UM47-1.2	G1397P	Neutral	0.376
NOTCH3	Q9UM47-1.2	G1397Q	Neutral	0.353
NOTCH3	Q9UM47-1.2	G1397R	Neutral	0.325
NOTCH3	Q9UM47-1.2	G1397S	Neutral	0.03
NOTCH3	Q9UM47-1.2	G1397T	Neutral	0.372
NOTCH3	Q9UM47-1.2	G1397V	Pathogenic	0.722
NOTCH3	Q9UM47-1.2	G1397W	Neutral	0.315
NOTCH3	Q9UM47-1.2	G1397Y	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	D1398A	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	D1398C	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	D1398E	Neutral	0.006
NOTCH3	Q9UM47-1.2	D1398F	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	D1398G	Neutral	0.327
NOTCH3	Q9UM47-1.2	D1398H	Neutral	0.341
NOTCH3	Q9UM47-1.2	D1398I	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	D1398K	Neutral	0.325
NOTCH3	Q9UM47-1.2	D1398L	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	D1398M	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	D1398N	Neutral	0.026
NOTCH3	Q9UM47-1.2	D1398P	Neutral	0.365
NOTCH3	Q9UM47-1.2	D1398Q	Neutral	0.103
NOTCH3	Q9UM47-1.2	D1398R	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	D1398S	Neutral	0.105
NOTCH3	Q9UM47-1.2	D1398T	Neutral	0.363
NOTCH3	Q9UM47-1.2	D1398V	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	D1398W	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	D1398Y	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	Q1399A	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q1399C	Neutral	0.085
NOTCH3	Q9UM47-1.2	Q1399D	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1399E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1399F	Neutral	0.088
NOTCH3	Q9UM47-1.2	Q1399G	Neutral	0.017
NOTCH3	Q9UM47-1.2	Q1399H	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1399I	Neutral	0.091
NOTCH3	Q9UM47-1.2	Q1399K	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1399L	Neutral	0.022
NOTCH3	Q9UM47-1.2	Q1399M	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1399N	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1399P	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q1399R	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1399S	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1399T	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q1399V	Neutral	0.022
NOTCH3	Q9UM47-1.2	Q1399W	Neutral	0.019
NOTCH3	Q9UM47-1.2	Q1399Y	Neutral	0.004
NOTCH3	Q9UM47-1.2	R1400A	Neutral	0.02
NOTCH3	Q9UM47-1.2	R1400C	Neutral	0.31
NOTCH3	Q9UM47-1.2	R1400D	Neutral	0.09
NOTCH3	Q9UM47-1.2	R1400E	Neutral	0.005
NOTCH3	Q9UM47-1.2	R1400F	Neutral	0.353
NOTCH3	Q9UM47-1.2	R1400G	Neutral	0.078
NOTCH3	Q9UM47-1.2	R1400H	Neutral	0.005
NOTCH3	Q9UM47-1.2	R1400I	Neutral	0.344
NOTCH3	Q9UM47-1.2	R1400K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R1400L	Neutral	0.103
NOTCH3	Q9UM47-1.2	R1400M	Neutral	0.025
NOTCH3	Q9UM47-1.2	R1400N	Neutral	0.005
NOTCH3	Q9UM47-1.2	R1400P	Neutral	0.091
NOTCH3	Q9UM47-1.2	R1400Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1400S	Neutral	0.02
NOTCH3	Q9UM47-1.2	R1400T	Neutral	0.022
NOTCH3	Q9UM47-1.2	R1400V	Neutral	0.326
NOTCH3	Q9UM47-1.2	R1400W	Neutral	0.353
NOTCH3	Q9UM47-1.2	R1400Y	Neutral	0.109
NOTCH3	Q9UM47-1.2	C1401A	Neutral	0.486
NOTCH3	Q9UM47-1.2	C1401D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1401E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1401F	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	C1401G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1401H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1401I	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	C1401K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1401L	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	C1401M	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	C1401N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1401P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1401Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1401R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1401S	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C1401T	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1401V	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	C1401W	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	C1401Y	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	D1402A	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	D1402C	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	D1402E	Neutral	0.011
NOTCH3	Q9UM47-1.2	D1402F	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	D1402G	Neutral	0.482
NOTCH3	Q9UM47-1.2	D1402H	Neutral	0.498
NOTCH3	Q9UM47-1.2	D1402I	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	D1402K	Neutral	0.48
NOTCH3	Q9UM47-1.2	D1402L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	D1402M	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	D1402N	Neutral	0.049
NOTCH3	Q9UM47-1.2	D1402P	Pathogenic	0.524
NOTCH3	Q9UM47-1.2	D1402Q	Neutral	0.181
NOTCH3	Q9UM47-1.2	D1402R	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	D1402S	Neutral	0.184
NOTCH3	Q9UM47-1.2	D1402T	Pathogenic	0.522
NOTCH3	Q9UM47-1.2	D1402V	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	D1402W	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	D1402Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	R1403A	Neutral	0.018
NOTCH3	Q9UM47-1.2	R1403C	Neutral	0.293
NOTCH3	Q9UM47-1.2	R1403D	Neutral	0.084
NOTCH3	Q9UM47-1.2	R1403E	Neutral	0.005
NOTCH3	Q9UM47-1.2	R1403F	Neutral	0.336
NOTCH3	Q9UM47-1.2	R1403G	Neutral	0.072
NOTCH3	Q9UM47-1.2	R1403H	Neutral	0.005
NOTCH3	Q9UM47-1.2	R1403I	Neutral	0.326
NOTCH3	Q9UM47-1.2	R1403K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R1403L	Neutral	0.096
NOTCH3	Q9UM47-1.2	R1403M	Neutral	0.023
NOTCH3	Q9UM47-1.2	R1403N	Neutral	0.004
NOTCH3	Q9UM47-1.2	R1403P	Neutral	0.085
NOTCH3	Q9UM47-1.2	R1403Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1403S	Neutral	0.019
NOTCH3	Q9UM47-1.2	R1403T	Neutral	0.02
NOTCH3	Q9UM47-1.2	R1403V	Neutral	0.309
NOTCH3	Q9UM47-1.2	R1403W	Neutral	0.335
NOTCH3	Q9UM47-1.2	R1403Y	Neutral	0.101
NOTCH3	Q9UM47-1.2	E1404A	Neutral	0.038
NOTCH3	Q9UM47-1.2	E1404C	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	E1404D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1404F	Neutral	0.469
NOTCH3	Q9UM47-1.2	E1404G	Neutral	0.143
NOTCH3	Q9UM47-1.2	E1404H	Neutral	0.01
NOTCH3	Q9UM47-1.2	E1404I	Neutral	0.479
NOTCH3	Q9UM47-1.2	E1404K	Neutral	0.002
NOTCH3	Q9UM47-1.2	E1404L	Neutral	0.479
NOTCH3	Q9UM47-1.2	E1404M	Neutral	0.167
NOTCH3	Q9UM47-1.2	E1404N	Neutral	0.01
NOTCH3	Q9UM47-1.2	E1404P	Neutral	0.042
NOTCH3	Q9UM47-1.2	E1404Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1404R	Neutral	0.009
NOTCH3	Q9UM47-1.2	E1404S	Neutral	0.009
NOTCH3	Q9UM47-1.2	E1404T	Neutral	0.042
NOTCH3	Q9UM47-1.2	E1404V	Neutral	0.173
NOTCH3	Q9UM47-1.2	E1404W	Neutral	0.443
NOTCH3	Q9UM47-1.2	E1404Y	Neutral	0.158
NOTCH3	Q9UM47-1.2	C1405A	Neutral	0.489
NOTCH3	Q9UM47-1.2	C1405D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1405E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1405F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C1405G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1405H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1405I	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C1405K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1405L	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C1405M	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C1405N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1405P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1405Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1405R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1405S	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	C1405T	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C1405V	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C1405W	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	C1405Y	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	N1406A	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	N1406C	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N1406D	Neutral	0.124
NOTCH3	Q9UM47-1.2	N1406E	Neutral	0.385
NOTCH3	Q9UM47-1.2	N1406F	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	N1406G	Neutral	0.355
NOTCH3	Q9UM47-1.2	N1406H	Neutral	0.118
NOTCH3	Q9UM47-1.2	N1406I	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	N1406K	Neutral	0.363
NOTCH3	Q9UM47-1.2	N1406L	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	N1406M	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	N1406P	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	N1406Q	Neutral	0.381
NOTCH3	Q9UM47-1.2	N1406R	Neutral	0.351
NOTCH3	Q9UM47-1.2	N1406S	Neutral	0.117
NOTCH3	Q9UM47-1.2	N1406T	Neutral	0.396
NOTCH3	Q9UM47-1.2	N1406V	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N1406W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N1406Y	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	S1407A	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1407C	Neutral	0.092
NOTCH3	Q9UM47-1.2	S1407D	Neutral	0.021
NOTCH3	Q9UM47-1.2	S1407E	Neutral	0.02
NOTCH3	Q9UM47-1.2	S1407F	Neutral	0.277
NOTCH3	Q9UM47-1.2	S1407G	Neutral	0.021
NOTCH3	Q9UM47-1.2	S1407H	Neutral	0.081
NOTCH3	Q9UM47-1.2	S1407I	Neutral	0.285
NOTCH3	Q9UM47-1.2	S1407K	Neutral	0.018
NOTCH3	Q9UM47-1.2	S1407L	Neutral	0.285
NOTCH3	Q9UM47-1.2	S1407M	Neutral	0.08
NOTCH3	Q9UM47-1.2	S1407N	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1407P	Neutral	0.09
NOTCH3	Q9UM47-1.2	S1407Q	Neutral	0.019
NOTCH3	Q9UM47-1.2	S1407R	Neutral	0.074
NOTCH3	Q9UM47-1.2	S1407T	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1407V	Neutral	0.299
NOTCH3	Q9UM47-1.2	S1407W	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	S1407Y	Neutral	0.271
NOTCH3	Q9UM47-1.2	P1408A	Neutral	0.02
NOTCH3	Q9UM47-1.2	P1408C	Neutral	0.317
NOTCH3	Q9UM47-1.2	P1408D	Neutral	0.022
NOTCH3	Q9UM47-1.2	P1408E	Neutral	0.021
NOTCH3	Q9UM47-1.2	P1408F	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	P1408G	Neutral	0.081
NOTCH3	Q9UM47-1.2	P1408H	Neutral	0.085
NOTCH3	Q9UM47-1.2	P1408I	Neutral	0.294
NOTCH3	Q9UM47-1.2	P1408K	Neutral	0.019
NOTCH3	Q9UM47-1.2	P1408L	Neutral	0.294
NOTCH3	Q9UM47-1.2	P1408M	Neutral	0.083
NOTCH3	Q9UM47-1.2	P1408N	Neutral	0.093
NOTCH3	Q9UM47-1.2	P1408Q	Neutral	0.02
NOTCH3	Q9UM47-1.2	P1408R	Neutral	0.077
NOTCH3	Q9UM47-1.2	P1408S	Neutral	0.021
NOTCH3	Q9UM47-1.2	P1408T	Neutral	0.022
NOTCH3	Q9UM47-1.2	P1408V	Neutral	0.089
NOTCH3	Q9UM47-1.2	P1408W	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	P1408Y	Neutral	0.279
NOTCH3	Q9UM47-1.2	G1409A	Neutral	0.003
NOTCH3	Q9UM47-1.2	G1409C	Neutral	0.201
NOTCH3	Q9UM47-1.2	G1409D	Neutral	0.012
NOTCH3	Q9UM47-1.2	G1409E	Neutral	0.048
NOTCH3	Q9UM47-1.2	G1409F	Neutral	0.173
NOTCH3	Q9UM47-1.2	G1409H	Neutral	0.046
NOTCH3	Q9UM47-1.2	G1409I	Neutral	0.499
NOTCH3	Q9UM47-1.2	G1409K	Neutral	0.044
NOTCH3	Q9UM47-1.2	G1409L	Neutral	0.498
NOTCH3	Q9UM47-1.2	G1409M	Neutral	0.179
NOTCH3	Q9UM47-1.2	G1409N	Neutral	0.003
NOTCH3	Q9UM47-1.2	G1409P	Neutral	0.051
NOTCH3	Q9UM47-1.2	G1409Q	Neutral	0.047
NOTCH3	Q9UM47-1.2	G1409R	Neutral	0.042
NOTCH3	Q9UM47-1.2	G1409S	Neutral	0.003
NOTCH3	Q9UM47-1.2	G1409T	Neutral	0.051
NOTCH3	Q9UM47-1.2	G1409V	Neutral	0.19
NOTCH3	Q9UM47-1.2	G1409W	Neutral	0.04
NOTCH3	Q9UM47-1.2	G1409Y	Neutral	0.169
NOTCH3	Q9UM47-1.2	C1410A	Neutral	0.494
NOTCH3	Q9UM47-1.2	C1410D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1410E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1410F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	C1410G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1410H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1410I	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C1410K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1410L	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C1410M	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C1410N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1410P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1410Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1410R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1410S	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C1410T	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C1410V	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C1410W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C1410Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	G1411A	Neutral	0.016
NOTCH3	Q9UM47-1.2	G1411C	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	G1411D	Neutral	0.063
NOTCH3	Q9UM47-1.2	G1411E	Neutral	0.222
NOTCH3	Q9UM47-1.2	G1411F	Pathogenic	0.543
NOTCH3	Q9UM47-1.2	G1411H	Neutral	0.215
NOTCH3	Q9UM47-1.2	G1411I	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	G1411K	Neutral	0.206
NOTCH3	Q9UM47-1.2	G1411L	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	G1411M	Pathogenic	0.552
NOTCH3	Q9UM47-1.2	G1411N	Neutral	0.014
NOTCH3	Q9UM47-1.2	G1411P	Neutral	0.235
NOTCH3	Q9UM47-1.2	G1411Q	Neutral	0.218
NOTCH3	Q9UM47-1.2	G1411R	Neutral	0.198
NOTCH3	Q9UM47-1.2	G1411S	Neutral	0.016
NOTCH3	Q9UM47-1.2	G1411T	Neutral	0.232
NOTCH3	Q9UM47-1.2	G1411V	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	G1411W	Neutral	0.19
NOTCH3	Q9UM47-1.2	G1411Y	Pathogenic	0.535
NOTCH3	Q9UM47-1.2	W1412A	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W1412C	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W1412D	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1412E	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W1412F	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	W1412G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	W1412H	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W1412I	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W1412K	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W1412L	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W1412M	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	W1412N	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1412P	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1412Q	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W1412R	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W1412S	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W1412T	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W1412V	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W1412Y	Neutral	0.459
NOTCH3	Q9UM47-1.2	D1413A	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	D1413C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D1413E	Neutral	0.032
NOTCH3	Q9UM47-1.2	D1413F	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D1413G	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	D1413H	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	D1413I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1413K	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	D1413L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1413M	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1413N	Neutral	0.136
NOTCH3	Q9UM47-1.2	D1413P	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	D1413Q	Neutral	0.402
NOTCH3	Q9UM47-1.2	D1413R	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	D1413S	Neutral	0.407
NOTCH3	Q9UM47-1.2	D1413T	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	D1413V	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1413W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1413Y	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	G1414A	Neutral	0.182
NOTCH3	Q9UM47-1.2	G1414C	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	G1414D	Neutral	0.481
NOTCH3	Q9UM47-1.2	G1414E	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	G1414F	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	G1414H	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	G1414I	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	G1414K	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	G1414L	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	G1414M	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	G1414N	Neutral	0.166
NOTCH3	Q9UM47-1.2	G1414P	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	G1414Q	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	G1414R	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	G1414S	Neutral	0.178
NOTCH3	Q9UM47-1.2	G1414T	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	G1414V	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	G1414W	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	G1414Y	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	G1415A	Neutral	0.141
NOTCH3	Q9UM47-1.2	G1415C	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	G1415D	Neutral	0.405
NOTCH3	Q9UM47-1.2	G1415E	Pathogenic	0.743
NOTCH3	Q9UM47-1.2	G1415F	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	G1415H	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	G1415I	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	G1415K	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	G1415L	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	G1415M	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	G1415N	Neutral	0.128
NOTCH3	Q9UM47-1.2	G1415P	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	G1415Q	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	G1415R	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	G1415S	Neutral	0.137
NOTCH3	Q9UM47-1.2	G1415T	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	G1415V	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	G1415W	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	G1415Y	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	D1416A	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	D1416C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1416E	Neutral	0.031
NOTCH3	Q9UM47-1.2	D1416F	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D1416G	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	D1416H	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	D1416I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1416K	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	D1416L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1416M	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1416N	Neutral	0.132
NOTCH3	Q9UM47-1.2	D1416P	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	D1416Q	Neutral	0.394
NOTCH3	Q9UM47-1.2	D1416R	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	D1416S	Neutral	0.399
NOTCH3	Q9UM47-1.2	D1416T	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	D1416V	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1416W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1416Y	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	C1417A	Neutral	0.492
NOTCH3	Q9UM47-1.2	C1417D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1417E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1417F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C1417G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1417H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1417I	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C1417K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1417L	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C1417M	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C1417N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1417P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1417Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1417R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1417S	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1417T	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C1417V	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C1417W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C1417Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	S1418A	Neutral	0.091
NOTCH3	Q9UM47-1.2	S1418C	Pathogenic	0.669
NOTCH3	Q9UM47-1.2	S1418D	Neutral	0.303
NOTCH3	Q9UM47-1.2	S1418E	Neutral	0.289
NOTCH3	Q9UM47-1.2	S1418F	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	S1418G	Neutral	0.296
NOTCH3	Q9UM47-1.2	S1418H	Pathogenic	0.64
NOTCH3	Q9UM47-1.2	S1418I	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	S1418K	Neutral	0.269
NOTCH3	Q9UM47-1.2	S1418L	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	S1418M	Pathogenic	0.637
NOTCH3	Q9UM47-1.2	S1418N	Neutral	0.086
NOTCH3	Q9UM47-1.2	S1418P	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	S1418Q	Neutral	0.284
NOTCH3	Q9UM47-1.2	S1418R	Pathogenic	0.614
NOTCH3	Q9UM47-1.2	S1418T	Neutral	0.086
NOTCH3	Q9UM47-1.2	S1418V	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	S1418W	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	S1418Y	Pathogenic	0.882
NOTCH3	Q9UM47-1.2	L1419A	Pathogenic	0.685
NOTCH3	Q9UM47-1.2	L1419C	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	L1419D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1419E	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1419F	Neutral	0.36
NOTCH3	Q9UM47-1.2	L1419G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1419H	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1419I	Neutral	0.028
NOTCH3	Q9UM47-1.2	L1419K	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	L1419M	Neutral	0.028
NOTCH3	Q9UM47-1.2	L1419N	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L1419P	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	L1419Q	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	L1419R	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	L1419S	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	L1419T	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	L1419V	Neutral	0.108
NOTCH3	Q9UM47-1.2	L1419W	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	L1419Y	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	S1420A	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1420C	Neutral	0.009
NOTCH3	Q9UM47-1.2	S1420D	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1420E	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1420F	Neutral	0.034
NOTCH3	Q9UM47-1.2	S1420G	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1420H	Neutral	0.008
NOTCH3	Q9UM47-1.2	S1420I	Neutral	0.036
NOTCH3	Q9UM47-1.2	S1420K	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1420L	Neutral	0.036
NOTCH3	Q9UM47-1.2	S1420M	Neutral	0.008
NOTCH3	Q9UM47-1.2	S1420N	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1420P	Neutral	0.009
NOTCH3	Q9UM47-1.2	S1420Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1420R	Neutral	0.007
NOTCH3	Q9UM47-1.2	S1420T	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1420V	Neutral	0.038
NOTCH3	Q9UM47-1.2	S1420W	Neutral	0.127
NOTCH3	Q9UM47-1.2	S1420Y	Neutral	0.033
NOTCH3	Q9UM47-1.2	V1421A	Neutral	0.01
NOTCH3	Q9UM47-1.2	V1421C	Neutral	0.048
NOTCH3	Q9UM47-1.2	V1421D	Pathogenic	0.517
NOTCH3	Q9UM47-1.2	V1421E	Neutral	0.196
NOTCH3	Q9UM47-1.2	V1421F	Neutral	0.046
NOTCH3	Q9UM47-1.2	V1421G	Neutral	0.474
NOTCH3	Q9UM47-1.2	V1421H	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	V1421I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V1421K	Neutral	0.181
NOTCH3	Q9UM47-1.2	V1421L	Neutral	0.002
NOTCH3	Q9UM47-1.2	V1421M	Neutral	0.002
NOTCH3	Q9UM47-1.2	V1421N	Pathogenic	0.522
NOTCH3	Q9UM47-1.2	V1421P	Neutral	0.188
NOTCH3	Q9UM47-1.2	V1421Q	Neutral	0.193
NOTCH3	Q9UM47-1.2	V1421R	Neutral	0.49
NOTCH3	Q9UM47-1.2	V1421S	Neutral	0.179
NOTCH3	Q9UM47-1.2	V1421T	Neutral	0.011
NOTCH3	Q9UM47-1.2	V1421W	Neutral	0.473
NOTCH3	Q9UM47-1.2	V1421Y	Neutral	0.045
NOTCH3	Q9UM47-1.2	G1422A	Neutral	0.001
NOTCH3	Q9UM47-1.2	G1422C	Neutral	0.048
NOTCH3	Q9UM47-1.2	G1422D	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1422E	Neutral	0.01
NOTCH3	Q9UM47-1.2	G1422F	Neutral	0.04
NOTCH3	Q9UM47-1.2	G1422H	Neutral	0.01
NOTCH3	Q9UM47-1.2	G1422I	Neutral	0.167
NOTCH3	Q9UM47-1.2	G1422K	Neutral	0.009
NOTCH3	Q9UM47-1.2	G1422L	Neutral	0.167
NOTCH3	Q9UM47-1.2	G1422M	Neutral	0.042
NOTCH3	Q9UM47-1.2	G1422N	Neutral	0.001
NOTCH3	Q9UM47-1.2	G1422P	Neutral	0.011
NOTCH3	Q9UM47-1.2	G1422Q	Neutral	0.01
NOTCH3	Q9UM47-1.2	G1422R	Neutral	0.009
NOTCH3	Q9UM47-1.2	G1422S	Neutral	0.001
NOTCH3	Q9UM47-1.2	G1422T	Neutral	0.011
NOTCH3	Q9UM47-1.2	G1422V	Neutral	0.045
NOTCH3	Q9UM47-1.2	G1422W	Neutral	0.008
NOTCH3	Q9UM47-1.2	G1422Y	Neutral	0.039
NOTCH3	Q9UM47-1.2	D1423A	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	D1423C	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	D1423E	Neutral	0.005
NOTCH3	Q9UM47-1.2	D1423F	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	D1423G	Neutral	0.305
NOTCH3	Q9UM47-1.2	D1423H	Neutral	0.319
NOTCH3	Q9UM47-1.2	D1423I	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	D1423K	Neutral	0.304
NOTCH3	Q9UM47-1.2	D1423L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	D1423M	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	D1423N	Neutral	0.024
NOTCH3	Q9UM47-1.2	D1423P	Neutral	0.342
NOTCH3	Q9UM47-1.2	D1423Q	Neutral	0.094
NOTCH3	Q9UM47-1.2	D1423R	Pathogenic	0.654
NOTCH3	Q9UM47-1.2	D1423S	Neutral	0.096
NOTCH3	Q9UM47-1.2	D1423T	Neutral	0.34
NOTCH3	Q9UM47-1.2	D1423V	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	D1423W	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	D1423Y	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	P1424A	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	P1424C	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	P1424D	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	P1424E	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	P1424F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P1424G	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	P1424H	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	P1424I	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	P1424K	Pathogenic	0.679
NOTCH3	Q9UM47-1.2	P1424L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P1424M	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	P1424N	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	P1424Q	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	P1424R	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	P1424S	Pathogenic	0.701
NOTCH3	Q9UM47-1.2	P1424T	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	P1424V	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	P1424W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P1424Y	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	W1425A	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1425C	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1425D	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1425E	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1425F	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	W1425G	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1425H	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1425I	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1425K	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1425L	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1425M	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	W1425N	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1425P	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1425Q	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1425R	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1425S	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1425T	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1425V	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1425Y	Pathogenic	0.576
NOTCH3	Q9UM47-1.2	R1426A	Neutral	0.032
NOTCH3	Q9UM47-1.2	R1426C	Neutral	0.423
NOTCH3	Q9UM47-1.2	R1426D	Neutral	0.139
NOTCH3	Q9UM47-1.2	R1426E	Neutral	0.008
NOTCH3	Q9UM47-1.2	R1426F	Neutral	0.471
NOTCH3	Q9UM47-1.2	R1426G	Neutral	0.121
NOTCH3	Q9UM47-1.2	R1426H	Neutral	0.009
NOTCH3	Q9UM47-1.2	R1426I	Neutral	0.461
NOTCH3	Q9UM47-1.2	R1426K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R1426L	Neutral	0.158
NOTCH3	Q9UM47-1.2	R1426M	Neutral	0.039
NOTCH3	Q9UM47-1.2	R1426N	Neutral	0.008
NOTCH3	Q9UM47-1.2	R1426P	Neutral	0.14
NOTCH3	Q9UM47-1.2	R1426Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1426S	Neutral	0.032
NOTCH3	Q9UM47-1.2	R1426T	Neutral	0.035
NOTCH3	Q9UM47-1.2	R1426V	Neutral	0.442
NOTCH3	Q9UM47-1.2	R1426W	Neutral	0.47
NOTCH3	Q9UM47-1.2	R1426Y	Neutral	0.166
NOTCH3	Q9UM47-1.2	Q1427A	Neutral	0.078
NOTCH3	Q9UM47-1.2	Q1427C	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	Q1427D	Neutral	0.02
NOTCH3	Q9UM47-1.2	Q1427E	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1427F	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	Q1427G	Neutral	0.262
NOTCH3	Q9UM47-1.2	Q1427H	Neutral	0.021
NOTCH3	Q9UM47-1.2	Q1427I	Pathogenic	0.67
NOTCH3	Q9UM47-1.2	Q1427K	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q1427L	Neutral	0.309
NOTCH3	Q9UM47-1.2	Q1427M	Neutral	0.021
NOTCH3	Q9UM47-1.2	Q1427N	Neutral	0.02
NOTCH3	Q9UM47-1.2	Q1427P	Neutral	0.084
NOTCH3	Q9UM47-1.2	Q1427R	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q1427S	Neutral	0.018
NOTCH3	Q9UM47-1.2	Q1427T	Neutral	0.085
NOTCH3	Q9UM47-1.2	Q1427V	Neutral	0.309
NOTCH3	Q9UM47-1.2	Q1427W	Neutral	0.278
NOTCH3	Q9UM47-1.2	Q1427Y	Neutral	0.084
NOTCH3	Q9UM47-1.2	C1428A	Neutral	0.5
NOTCH3	Q9UM47-1.2	C1428D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1428E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1428F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	C1428G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1428H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1428I	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C1428K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1428L	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C1428M	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	C1428N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1428P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1428Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1428R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1428S	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C1428T	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C1428V	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1428W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C1428Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	E1429A	Neutral	0.014
NOTCH3	Q9UM47-1.2	E1429C	Pathogenic	0.583
NOTCH3	Q9UM47-1.2	E1429D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1429F	Neutral	0.234
NOTCH3	Q9UM47-1.2	E1429G	Neutral	0.055
NOTCH3	Q9UM47-1.2	E1429H	Neutral	0.003
NOTCH3	Q9UM47-1.2	E1429I	Neutral	0.242
NOTCH3	Q9UM47-1.2	E1429K	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1429L	Neutral	0.242
NOTCH3	Q9UM47-1.2	E1429M	Neutral	0.065
NOTCH3	Q9UM47-1.2	E1429N	Neutral	0.003
NOTCH3	Q9UM47-1.2	E1429P	Neutral	0.015
NOTCH3	Q9UM47-1.2	E1429Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1429R	Neutral	0.003
NOTCH3	Q9UM47-1.2	E1429S	Neutral	0.003
NOTCH3	Q9UM47-1.2	E1429T	Neutral	0.015
NOTCH3	Q9UM47-1.2	E1429V	Neutral	0.068
NOTCH3	Q9UM47-1.2	E1429W	Neutral	0.216
NOTCH3	Q9UM47-1.2	E1429Y	Neutral	0.061
NOTCH3	Q9UM47-1.2	A1430C	Neutral	0.02
NOTCH3	Q9UM47-1.2	A1430D	Neutral	0.292
NOTCH3	Q9UM47-1.2	A1430E	Neutral	0.078
NOTCH3	Q9UM47-1.2	A1430F	Neutral	0.259
NOTCH3	Q9UM47-1.2	A1430G	Neutral	0.02
NOTCH3	Q9UM47-1.2	A1430H	Neutral	0.27
NOTCH3	Q9UM47-1.2	A1430I	Neutral	0.074
NOTCH3	Q9UM47-1.2	A1430K	Neutral	0.071
NOTCH3	Q9UM47-1.2	A1430L	Neutral	0.074
NOTCH3	Q9UM47-1.2	A1430M	Neutral	0.074
NOTCH3	Q9UM47-1.2	A1430N	Neutral	0.288
NOTCH3	Q9UM47-1.2	A1430P	Neutral	0.083
NOTCH3	Q9UM47-1.2	A1430Q	Neutral	0.076
NOTCH3	Q9UM47-1.2	A1430R	Neutral	0.068
NOTCH3	Q9UM47-1.2	A1430S	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1430T	Neutral	0.019
NOTCH3	Q9UM47-1.2	A1430V	Neutral	0.018
NOTCH3	Q9UM47-1.2	A1430W	Pathogenic	0.589
NOTCH3	Q9UM47-1.2	A1430Y	Neutral	0.253
NOTCH3	Q9UM47-1.2	L1431A	Neutral	0.339
NOTCH3	Q9UM47-1.2	L1431C	Neutral	0.354
NOTCH3	Q9UM47-1.2	L1431D	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1431E	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	L1431F	Neutral	0.117
NOTCH3	Q9UM47-1.2	L1431G	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	L1431H	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	L1431I	Neutral	0.007
NOTCH3	Q9UM47-1.2	L1431K	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	L1431M	Neutral	0.007
NOTCH3	Q9UM47-1.2	L1431N	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	L1431P	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	L1431Q	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	L1431R	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	L1431S	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	L1431T	Neutral	0.362
NOTCH3	Q9UM47-1.2	L1431V	Neutral	0.028
NOTCH3	Q9UM47-1.2	L1431W	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	L1431Y	Neutral	0.373
NOTCH3	Q9UM47-1.2	Q1432A	Neutral	0.237
NOTCH3	Q9UM47-1.2	Q1432C	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	Q1432D	Neutral	0.07
NOTCH3	Q9UM47-1.2	Q1432E	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q1432F	Pathogenic	0.878
NOTCH3	Q9UM47-1.2	Q1432G	Pathogenic	0.568
NOTCH3	Q9UM47-1.2	Q1432H	Neutral	0.075
NOTCH3	Q9UM47-1.2	Q1432I	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	Q1432K	Neutral	0.016
NOTCH3	Q9UM47-1.2	Q1432L	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	Q1432M	Neutral	0.074
NOTCH3	Q9UM47-1.2	Q1432N	Neutral	0.071
NOTCH3	Q9UM47-1.2	Q1432P	Neutral	0.254
NOTCH3	Q9UM47-1.2	Q1432R	Neutral	0.016
NOTCH3	Q9UM47-1.2	Q1432S	Neutral	0.065
NOTCH3	Q9UM47-1.2	Q1432T	Neutral	0.256
NOTCH3	Q9UM47-1.2	Q1432V	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	Q1432W	Pathogenic	0.588
NOTCH3	Q9UM47-1.2	Q1432Y	Neutral	0.252
NOTCH3	Q9UM47-1.2	C1433A	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	C1433D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1433E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1433F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	C1433G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1433H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1433I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1433K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1433L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1433M	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C1433N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1433P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1433Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1433R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1433S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	C1433T	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	C1433V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	C1433W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C1433Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	W1434A	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W1434C	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1434D	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1434E	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1434F	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	W1434G	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W1434H	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1434I	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1434K	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1434L	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1434M	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	W1434N	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1434P	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1434Q	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1434R	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1434S	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W1434T	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1434V	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W1434Y	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	R1435A	Neutral	0.092
NOTCH3	Q9UM47-1.2	R1435C	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	R1435D	Neutral	0.335
NOTCH3	Q9UM47-1.2	R1435E	Neutral	0.025
NOTCH3	Q9UM47-1.2	R1435F	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	R1435G	Neutral	0.3
NOTCH3	Q9UM47-1.2	R1435H	Neutral	0.026
NOTCH3	Q9UM47-1.2	R1435I	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	R1435K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1435L	Neutral	0.368
NOTCH3	Q9UM47-1.2	R1435M	Neutral	0.113
NOTCH3	Q9UM47-1.2	R1435N	Neutral	0.024
NOTCH3	Q9UM47-1.2	R1435P	Neutral	0.337
NOTCH3	Q9UM47-1.2	R1435Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	R1435S	Neutral	0.094
NOTCH3	Q9UM47-1.2	R1435T	Neutral	0.101
NOTCH3	Q9UM47-1.2	R1435V	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	R1435W	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	R1435Y	Neutral	0.382
NOTCH3	Q9UM47-1.2	L1436A	Neutral	0.066
NOTCH3	Q9UM47-1.2	L1436C	Neutral	0.07
NOTCH3	Q9UM47-1.2	L1436D	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	L1436E	Pathogenic	0.635
NOTCH3	Q9UM47-1.2	L1436F	Neutral	0.018
NOTCH3	Q9UM47-1.2	L1436G	Pathogenic	0.862
NOTCH3	Q9UM47-1.2	L1436H	Pathogenic	0.641
NOTCH3	Q9UM47-1.2	L1436I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1436K	Neutral	0.28
NOTCH3	Q9UM47-1.2	L1436M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1436N	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	L1436P	Pathogenic	0.615
NOTCH3	Q9UM47-1.2	L1436Q	Neutral	0.28
NOTCH3	Q9UM47-1.2	L1436R	Neutral	0.27
NOTCH3	Q9UM47-1.2	L1436S	Neutral	0.249
NOTCH3	Q9UM47-1.2	L1436T	Neutral	0.073
NOTCH3	Q9UM47-1.2	L1436V	Neutral	0.004
NOTCH3	Q9UM47-1.2	L1436W	Neutral	0.255
NOTCH3	Q9UM47-1.2	L1436Y	Neutral	0.076
NOTCH3	Q9UM47-1.2	F1437A	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	F1437C	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	F1437D	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	F1437E	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	F1437G	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	F1437H	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	F1437I	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	F1437K	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	F1437L	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	F1437M	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	F1437N	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	F1437P	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	F1437Q	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	F1437R	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	F1437S	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	F1437T	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	F1437V	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	F1437W	Neutral	0.253
NOTCH3	Q9UM47-1.2	F1437Y	Neutral	0.018
NOTCH3	Q9UM47-1.2	N1438A	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	N1438C	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	N1438D	Neutral	0.066
NOTCH3	Q9UM47-1.2	N1438E	Neutral	0.236
NOTCH3	Q9UM47-1.2	N1438F	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	N1438G	Neutral	0.214
NOTCH3	Q9UM47-1.2	N1438H	Neutral	0.062
NOTCH3	Q9UM47-1.2	N1438I	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	N1438K	Neutral	0.219
NOTCH3	Q9UM47-1.2	N1438L	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	N1438M	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	N1438P	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	N1438Q	Neutral	0.233
NOTCH3	Q9UM47-1.2	N1438R	Neutral	0.211
NOTCH3	Q9UM47-1.2	N1438S	Neutral	0.062
NOTCH3	Q9UM47-1.2	N1438T	Neutral	0.245
NOTCH3	Q9UM47-1.2	N1438V	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	N1438W	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	N1438Y	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	N1439A	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	N1439C	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	N1439D	Neutral	0.028
NOTCH3	Q9UM47-1.2	N1439E	Neutral	0.111
NOTCH3	Q9UM47-1.2	N1439F	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	N1439G	Neutral	0.099
NOTCH3	Q9UM47-1.2	N1439H	Neutral	0.026
NOTCH3	Q9UM47-1.2	N1439I	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	N1439K	Neutral	0.102
NOTCH3	Q9UM47-1.2	N1439L	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	N1439M	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	N1439P	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	N1439Q	Neutral	0.109
NOTCH3	Q9UM47-1.2	N1439R	Neutral	0.097
NOTCH3	Q9UM47-1.2	N1439S	Neutral	0.026
NOTCH3	Q9UM47-1.2	N1439T	Neutral	0.115
NOTCH3	Q9UM47-1.2	N1439V	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	N1439W	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	N1439Y	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	S1440A	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1440C	Neutral	0.043
NOTCH3	Q9UM47-1.2	S1440D	Neutral	0.01
NOTCH3	Q9UM47-1.2	S1440E	Neutral	0.009
NOTCH3	Q9UM47-1.2	S1440F	Neutral	0.145
NOTCH3	Q9UM47-1.2	S1440G	Neutral	0.009
NOTCH3	Q9UM47-1.2	S1440H	Neutral	0.038
NOTCH3	Q9UM47-1.2	S1440I	Neutral	0.15
NOTCH3	Q9UM47-1.2	S1440K	Neutral	0.008
NOTCH3	Q9UM47-1.2	S1440L	Neutral	0.15
NOTCH3	Q9UM47-1.2	S1440M	Neutral	0.037
NOTCH3	Q9UM47-1.2	S1440N	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1440P	Neutral	0.042
NOTCH3	Q9UM47-1.2	S1440Q	Neutral	0.009
NOTCH3	Q9UM47-1.2	S1440R	Neutral	0.034
NOTCH3	Q9UM47-1.2	S1440T	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1440V	Neutral	0.159
NOTCH3	Q9UM47-1.2	S1440W	Neutral	0.41
NOTCH3	Q9UM47-1.2	S1440Y	Neutral	0.141
NOTCH3	Q9UM47-1.2	R1441A	Neutral	0.054
NOTCH3	Q9UM47-1.2	R1441C	Pathogenic	0.562
NOTCH3	Q9UM47-1.2	R1441D	Neutral	0.221
NOTCH3	Q9UM47-1.2	R1441E	Neutral	0.014
NOTCH3	Q9UM47-1.2	R1441F	Pathogenic	0.61
NOTCH3	Q9UM47-1.2	R1441G	Neutral	0.195
NOTCH3	Q9UM47-1.2	R1441H	Neutral	0.015
NOTCH3	Q9UM47-1.2	R1441I	Pathogenic	0.6
NOTCH3	Q9UM47-1.2	R1441K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1441L	Neutral	0.247
NOTCH3	Q9UM47-1.2	R1441M	Neutral	0.067
NOTCH3	Q9UM47-1.2	R1441N	Neutral	0.014
NOTCH3	Q9UM47-1.2	R1441P	Neutral	0.222
NOTCH3	Q9UM47-1.2	R1441Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R1441S	Neutral	0.055
NOTCH3	Q9UM47-1.2	R1441T	Neutral	0.06
NOTCH3	Q9UM47-1.2	R1441V	Pathogenic	0.581
NOTCH3	Q9UM47-1.2	R1441W	Pathogenic	0.609
NOTCH3	Q9UM47-1.2	R1441Y	Neutral	0.259
NOTCH3	Q9UM47-1.2	C1442A	Pathogenic	0.5
NOTCH3	Q9UM47-1.2	C1442D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1442E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1442F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	C1442G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1442H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1442I	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C1442K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1442L	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C1442M	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C1442N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1442P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1442Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1442R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1442S	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	C1442T	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	C1442V	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C1442W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C1442Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	D1443A	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	D1443C	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	D1443E	Neutral	0.022
NOTCH3	Q9UM47-1.2	D1443F	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	D1443G	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	D1443H	Pathogenic	0.672
NOTCH3	Q9UM47-1.2	D1443I	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	D1443K	Pathogenic	0.656
NOTCH3	Q9UM47-1.2	D1443L	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D1443M	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	D1443N	Neutral	0.097
NOTCH3	Q9UM47-1.2	D1443P	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	D1443Q	Neutral	0.313
NOTCH3	Q9UM47-1.2	D1443R	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	D1443S	Neutral	0.318
NOTCH3	Q9UM47-1.2	D1443T	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	D1443V	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	D1443W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	D1443Y	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	P1444A	Neutral	0.013
NOTCH3	Q9UM47-1.2	P1444C	Neutral	0.224
NOTCH3	Q9UM47-1.2	P1444D	Neutral	0.014
NOTCH3	Q9UM47-1.2	P1444E	Neutral	0.013
NOTCH3	Q9UM47-1.2	P1444F	Pathogenic	0.531
NOTCH3	Q9UM47-1.2	P1444G	Neutral	0.052
NOTCH3	Q9UM47-1.2	P1444H	Neutral	0.055
NOTCH3	Q9UM47-1.2	P1444I	Neutral	0.206
NOTCH3	Q9UM47-1.2	P1444K	Neutral	0.012
NOTCH3	Q9UM47-1.2	P1444L	Neutral	0.206
NOTCH3	Q9UM47-1.2	P1444M	Neutral	0.054
NOTCH3	Q9UM47-1.2	P1444N	Neutral	0.06
NOTCH3	Q9UM47-1.2	P1444Q	Neutral	0.013
NOTCH3	Q9UM47-1.2	P1444R	Neutral	0.05
NOTCH3	Q9UM47-1.2	P1444S	Neutral	0.013
NOTCH3	Q9UM47-1.2	P1444T	Neutral	0.014
NOTCH3	Q9UM47-1.2	P1444V	Neutral	0.057
NOTCH3	Q9UM47-1.2	P1444W	Pathogenic	0.505
NOTCH3	Q9UM47-1.2	P1444Y	Neutral	0.194
NOTCH3	Q9UM47-1.2	A1445C	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1445D	Neutral	0.074
NOTCH3	Q9UM47-1.2	A1445E	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1445F	Neutral	0.064
NOTCH3	Q9UM47-1.2	A1445G	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1445H	Neutral	0.067
NOTCH3	Q9UM47-1.2	A1445I	Neutral	0.015
NOTCH3	Q9UM47-1.2	A1445K	Neutral	0.015
NOTCH3	Q9UM47-1.2	A1445L	Neutral	0.015
NOTCH3	Q9UM47-1.2	A1445M	Neutral	0.015
NOTCH3	Q9UM47-1.2	A1445N	Neutral	0.073
NOTCH3	Q9UM47-1.2	A1445P	Neutral	0.017
NOTCH3	Q9UM47-1.2	A1445Q	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1445R	Neutral	0.014
NOTCH3	Q9UM47-1.2	A1445S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1445T	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1445V	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1445W	Neutral	0.218
NOTCH3	Q9UM47-1.2	A1445Y	Neutral	0.062
NOTCH3	Q9UM47-1.2	C1446A	Neutral	0.492
NOTCH3	Q9UM47-1.2	C1446D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1446E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1446F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C1446G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1446H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1446I	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C1446K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1446L	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C1446M	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C1446N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1446P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1446Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1446R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1446S	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	C1446T	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C1446V	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C1446W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C1446Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	S1447A	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1447C	Neutral	0.037
NOTCH3	Q9UM47-1.2	S1447D	Neutral	0.008
NOTCH3	Q9UM47-1.2	S1447E	Neutral	0.008
NOTCH3	Q9UM47-1.2	S1447F	Neutral	0.127
NOTCH3	Q9UM47-1.2	S1447G	Neutral	0.008
NOTCH3	Q9UM47-1.2	S1447H	Neutral	0.033
NOTCH3	Q9UM47-1.2	S1447I	Neutral	0.132
NOTCH3	Q9UM47-1.2	S1447K	Neutral	0.007
NOTCH3	Q9UM47-1.2	S1447L	Neutral	0.132
NOTCH3	Q9UM47-1.2	S1447M	Neutral	0.032
NOTCH3	Q9UM47-1.2	S1447N	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1447P	Neutral	0.036
NOTCH3	Q9UM47-1.2	S1447Q	Neutral	0.007
NOTCH3	Q9UM47-1.2	S1447R	Neutral	0.029
NOTCH3	Q9UM47-1.2	S1447T	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1447V	Neutral	0.14
NOTCH3	Q9UM47-1.2	S1447W	Neutral	0.374
NOTCH3	Q9UM47-1.2	S1447Y	Neutral	0.124
NOTCH3	Q9UM47-1.2	S1448A	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1448C	Neutral	0.102
NOTCH3	Q9UM47-1.2	S1448D	Neutral	0.024
NOTCH3	Q9UM47-1.2	S1448E	Neutral	0.022
NOTCH3	Q9UM47-1.2	S1448F	Neutral	0.301
NOTCH3	Q9UM47-1.2	S1448G	Neutral	0.023
NOTCH3	Q9UM47-1.2	S1448H	Neutral	0.091
NOTCH3	Q9UM47-1.2	S1448I	Neutral	0.311
NOTCH3	Q9UM47-1.2	S1448K	Neutral	0.02
NOTCH3	Q9UM47-1.2	S1448L	Neutral	0.31
NOTCH3	Q9UM47-1.2	S1448M	Neutral	0.09
NOTCH3	Q9UM47-1.2	S1448N	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1448P	Neutral	0.101
NOTCH3	Q9UM47-1.2	S1448Q	Neutral	0.022
NOTCH3	Q9UM47-1.2	S1448R	Neutral	0.082
NOTCH3	Q9UM47-1.2	S1448T	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1448V	Neutral	0.325
NOTCH3	Q9UM47-1.2	S1448W	Pathogenic	0.639
NOTCH3	Q9UM47-1.2	S1448Y	Neutral	0.295
NOTCH3	Q9UM47-1.2	P1449A	Neutral	0.099
NOTCH3	Q9UM47-1.2	P1449C	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	P1449D	Neutral	0.107
NOTCH3	Q9UM47-1.2	P1449E	Neutral	0.101
NOTCH3	Q9UM47-1.2	P1449F	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	P1449G	Neutral	0.317
NOTCH3	Q9UM47-1.2	P1449H	Neutral	0.328
NOTCH3	Q9UM47-1.2	P1449I	Pathogenic	0.686
NOTCH3	Q9UM47-1.2	P1449K	Neutral	0.092
NOTCH3	Q9UM47-1.2	P1449L	Pathogenic	0.686
NOTCH3	Q9UM47-1.2	P1449M	Neutral	0.323
NOTCH3	Q9UM47-1.2	P1449N	Neutral	0.349
NOTCH3	Q9UM47-1.2	P1449Q	Neutral	0.099
NOTCH3	Q9UM47-1.2	P1449R	Neutral	0.305
NOTCH3	Q9UM47-1.2	P1449S	Neutral	0.101
NOTCH3	Q9UM47-1.2	P1449T	Neutral	0.106
NOTCH3	Q9UM47-1.2	P1449V	Neutral	0.339
NOTCH3	Q9UM47-1.2	P1449W	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	P1449Y	Pathogenic	0.67
NOTCH3	Q9UM47-1.2	A1450C	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1450D	Neutral	0.11
NOTCH3	Q9UM47-1.2	A1450E	Neutral	0.025
NOTCH3	Q9UM47-1.2	A1450F	Neutral	0.095
NOTCH3	Q9UM47-1.2	A1450G	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1450H	Neutral	0.099
NOTCH3	Q9UM47-1.2	A1450I	Neutral	0.023
NOTCH3	Q9UM47-1.2	A1450K	Neutral	0.022
NOTCH3	Q9UM47-1.2	A1450L	Neutral	0.023
NOTCH3	Q9UM47-1.2	A1450M	Neutral	0.023
NOTCH3	Q9UM47-1.2	A1450N	Neutral	0.108
NOTCH3	Q9UM47-1.2	A1450P	Neutral	0.026
NOTCH3	Q9UM47-1.2	A1450Q	Neutral	0.024
NOTCH3	Q9UM47-1.2	A1450R	Neutral	0.021
NOTCH3	Q9UM47-1.2	A1450S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1450T	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1450V	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1450W	Neutral	0.3
NOTCH3	Q9UM47-1.2	A1450Y	Neutral	0.092
NOTCH3	Q9UM47-1.2	C1451A	Neutral	0.493
NOTCH3	Q9UM47-1.2	C1451D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1451E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1451F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C1451G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1451H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1451I	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C1451K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1451L	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	C1451M	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	C1451N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1451P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1451Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1451R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1451S	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C1451T	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C1451V	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	C1451W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	C1451Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	L1452A	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	L1452C	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	L1452D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1452E	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1452F	Neutral	0.365
NOTCH3	Q9UM47-1.2	L1452G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1452H	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1452I	Neutral	0.028
NOTCH3	Q9UM47-1.2	L1452K	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	L1452M	Neutral	0.028
NOTCH3	Q9UM47-1.2	L1452N	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L1452P	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	L1452Q	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	L1452R	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	L1452S	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	L1452T	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	L1452V	Neutral	0.109
NOTCH3	Q9UM47-1.2	L1452W	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	L1452Y	Pathogenic	0.72
NOTCH3	Q9UM47-1.2	Y1453A	Pathogenic	0.863
NOTCH3	Q9UM47-1.2	Y1453C	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	Y1453D	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	Y1453E	Pathogenic	0.882
NOTCH3	Q9UM47-1.2	Y1453F	Neutral	0.004
NOTCH3	Q9UM47-1.2	Y1453G	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	Y1453H	Neutral	0.018
NOTCH3	Q9UM47-1.2	Y1453I	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	Y1453K	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	Y1453L	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	Y1453M	Pathogenic	0.633
NOTCH3	Q9UM47-1.2	Y1453N	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	Y1453P	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	Y1453Q	Pathogenic	0.626
NOTCH3	Q9UM47-1.2	Y1453R	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	Y1453S	Pathogenic	0.867
NOTCH3	Q9UM47-1.2	Y1453T	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	Y1453V	Pathogenic	0.616
NOTCH3	Q9UM47-1.2	Y1453W	Neutral	0.018
NOTCH3	Q9UM47-1.2	D1454A	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	D1454C	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	D1454E	Neutral	0.034
NOTCH3	Q9UM47-1.2	D1454F	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1454G	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	D1454H	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	D1454I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1454K	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	D1454L	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	D1454M	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1454N	Neutral	0.145
NOTCH3	Q9UM47-1.2	D1454P	Pathogenic	0.782
NOTCH3	Q9UM47-1.2	D1454Q	Neutral	0.419
NOTCH3	Q9UM47-1.2	D1454R	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	D1454S	Neutral	0.424
NOTCH3	Q9UM47-1.2	D1454T	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	D1454V	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D1454W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1454Y	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N1455A	Pathogenic	0.636
NOTCH3	Q9UM47-1.2	N1455C	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	N1455D	Neutral	0.02
NOTCH3	Q9UM47-1.2	N1455E	Neutral	0.082
NOTCH3	Q9UM47-1.2	N1455F	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	N1455G	Neutral	0.073
NOTCH3	Q9UM47-1.2	N1455H	Neutral	0.019
NOTCH3	Q9UM47-1.2	N1455I	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	N1455K	Neutral	0.075
NOTCH3	Q9UM47-1.2	N1455L	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	N1455M	Pathogenic	0.639
NOTCH3	Q9UM47-1.2	N1455P	Pathogenic	0.657
NOTCH3	Q9UM47-1.2	N1455Q	Neutral	0.081
NOTCH3	Q9UM47-1.2	N1455R	Neutral	0.071
NOTCH3	Q9UM47-1.2	N1455S	Neutral	0.019
NOTCH3	Q9UM47-1.2	N1455T	Neutral	0.085
NOTCH3	Q9UM47-1.2	N1455V	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	N1455W	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	N1455Y	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	F1456A	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	F1456C	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	F1456D	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	F1456E	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	F1456G	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	F1456H	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	F1456I	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	F1456K	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	F1456L	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	F1456M	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	F1456N	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	F1456P	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	F1456Q	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	F1456R	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	F1456S	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	F1456T	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	F1456V	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	F1456W	Neutral	0.305
NOTCH3	Q9UM47-1.2	F1456Y	Neutral	0.023
NOTCH3	Q9UM47-1.2	D1457A	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	D1457C	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	D1457E	Neutral	0.008
NOTCH3	Q9UM47-1.2	D1457F	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	D1457G	Neutral	0.396
NOTCH3	Q9UM47-1.2	D1457H	Neutral	0.411
NOTCH3	Q9UM47-1.2	D1457I	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	D1457K	Neutral	0.394
NOTCH3	Q9UM47-1.2	D1457L	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1457M	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	D1457N	Neutral	0.035
NOTCH3	Q9UM47-1.2	D1457P	Neutral	0.436
NOTCH3	Q9UM47-1.2	D1457Q	Neutral	0.134
NOTCH3	Q9UM47-1.2	D1457R	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	D1457S	Neutral	0.137
NOTCH3	Q9UM47-1.2	D1457T	Neutral	0.434
NOTCH3	Q9UM47-1.2	D1457V	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	D1457W	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D1457Y	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	C1458A	Neutral	0.498
NOTCH3	Q9UM47-1.2	C1458D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1458E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1458F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	C1458G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1458H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1458I	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C1458K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1458L	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C1458M	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C1458N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1458P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1458Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1458R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1458S	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C1458T	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C1458V	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C1458W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C1458Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	H1459A	Neutral	0.13
NOTCH3	Q9UM47-1.2	H1459C	Neutral	0.425
NOTCH3	Q9UM47-1.2	H1459D	Neutral	0.035
NOTCH3	Q9UM47-1.2	H1459E	Neutral	0.008
NOTCH3	Q9UM47-1.2	H1459F	Neutral	0.037
NOTCH3	Q9UM47-1.2	H1459G	Neutral	0.122
NOTCH3	Q9UM47-1.2	H1459I	Neutral	0.451
NOTCH3	Q9UM47-1.2	H1459K	Neutral	0.036
NOTCH3	Q9UM47-1.2	H1459L	Neutral	0.451
NOTCH3	Q9UM47-1.2	H1459M	Neutral	0.152
NOTCH3	Q9UM47-1.2	H1459N	Neutral	0.002
NOTCH3	Q9UM47-1.2	H1459P	Neutral	0.141
NOTCH3	Q9UM47-1.2	H1459Q	Neutral	0.009
NOTCH3	Q9UM47-1.2	H1459R	Neutral	0.008
NOTCH3	Q9UM47-1.2	H1459S	Neutral	0.033
NOTCH3	Q9UM47-1.2	H1459T	Neutral	0.142
NOTCH3	Q9UM47-1.2	H1459V	Neutral	0.443
NOTCH3	Q9UM47-1.2	H1459W	Neutral	0.135
NOTCH3	Q9UM47-1.2	H1459Y	Neutral	0.0
NOTCH3	Q9UM47-1.2	A1460C	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1460D	Neutral	0.105
NOTCH3	Q9UM47-1.2	A1460E	Neutral	0.023
NOTCH3	Q9UM47-1.2	A1460F	Neutral	0.09
NOTCH3	Q9UM47-1.2	A1460G	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1460H	Neutral	0.095
NOTCH3	Q9UM47-1.2	A1460I	Neutral	0.022
NOTCH3	Q9UM47-1.2	A1460K	Neutral	0.021
NOTCH3	Q9UM47-1.2	A1460L	Neutral	0.022
NOTCH3	Q9UM47-1.2	A1460M	Neutral	0.022
NOTCH3	Q9UM47-1.2	A1460N	Neutral	0.103
NOTCH3	Q9UM47-1.2	A1460P	Neutral	0.025
NOTCH3	Q9UM47-1.2	A1460Q	Neutral	0.023
NOTCH3	Q9UM47-1.2	A1460R	Neutral	0.02
NOTCH3	Q9UM47-1.2	A1460S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1460T	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1460V	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1460W	Neutral	0.29
NOTCH3	Q9UM47-1.2	A1460Y	Neutral	0.088
NOTCH3	Q9UM47-1.2	G1461A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1461C	Neutral	0.134
NOTCH3	Q9UM47-1.2	G1461D	Neutral	0.007
NOTCH3	Q9UM47-1.2	G1461E	Neutral	0.03
NOTCH3	Q9UM47-1.2	G1461F	Neutral	0.114
NOTCH3	Q9UM47-1.2	G1461H	Neutral	0.029
NOTCH3	Q9UM47-1.2	G1461I	Neutral	0.379
NOTCH3	Q9UM47-1.2	G1461K	Neutral	0.027
NOTCH3	Q9UM47-1.2	G1461L	Neutral	0.379
NOTCH3	Q9UM47-1.2	G1461M	Neutral	0.118
NOTCH3	Q9UM47-1.2	G1461N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1461P	Neutral	0.032
NOTCH3	Q9UM47-1.2	G1461Q	Neutral	0.029
NOTCH3	Q9UM47-1.2	G1461R	Neutral	0.026
NOTCH3	Q9UM47-1.2	G1461S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1461T	Neutral	0.032
NOTCH3	Q9UM47-1.2	G1461V	Neutral	0.126
NOTCH3	Q9UM47-1.2	G1461W	Neutral	0.025
NOTCH3	Q9UM47-1.2	G1461Y	Neutral	0.111
NOTCH3	Q9UM47-1.2	G1462A	Neutral	0.005
NOTCH3	Q9UM47-1.2	G1462C	Neutral	0.306
NOTCH3	Q9UM47-1.2	G1462D	Neutral	0.02
NOTCH3	Q9UM47-1.2	G1462E	Neutral	0.081
NOTCH3	Q9UM47-1.2	G1462F	Neutral	0.269
NOTCH3	Q9UM47-1.2	G1462H	Neutral	0.078
NOTCH3	Q9UM47-1.2	G1462I	Pathogenic	0.636
NOTCH3	Q9UM47-1.2	G1462K	Neutral	0.074
NOTCH3	Q9UM47-1.2	G1462L	Pathogenic	0.636
NOTCH3	Q9UM47-1.2	G1462M	Neutral	0.276
NOTCH3	Q9UM47-1.2	G1462N	Neutral	0.004
NOTCH3	Q9UM47-1.2	G1462P	Neutral	0.087
NOTCH3	Q9UM47-1.2	G1462Q	Neutral	0.08
NOTCH3	Q9UM47-1.2	G1462R	Neutral	0.071
NOTCH3	Q9UM47-1.2	G1462S	Neutral	0.005
NOTCH3	Q9UM47-1.2	G1462T	Neutral	0.086
NOTCH3	Q9UM47-1.2	G1462V	Neutral	0.291
NOTCH3	Q9UM47-1.2	G1462W	Neutral	0.068
NOTCH3	Q9UM47-1.2	G1462Y	Neutral	0.263
NOTCH3	Q9UM47-1.2	R1463A	Neutral	0.015
NOTCH3	Q9UM47-1.2	R1463C	Neutral	0.26
NOTCH3	Q9UM47-1.2	R1463D	Neutral	0.072
NOTCH3	Q9UM47-1.2	R1463E	Neutral	0.004
NOTCH3	Q9UM47-1.2	R1463F	Neutral	0.299
NOTCH3	Q9UM47-1.2	R1463G	Neutral	0.062
NOTCH3	Q9UM47-1.2	R1463H	Neutral	0.004
NOTCH3	Q9UM47-1.2	R1463I	Neutral	0.291
NOTCH3	Q9UM47-1.2	R1463K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R1463L	Neutral	0.083
NOTCH3	Q9UM47-1.2	R1463M	Neutral	0.019
NOTCH3	Q9UM47-1.2	R1463N	Neutral	0.004
NOTCH3	Q9UM47-1.2	R1463P	Neutral	0.073
NOTCH3	Q9UM47-1.2	R1463Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1463S	Neutral	0.016
NOTCH3	Q9UM47-1.2	R1463T	Neutral	0.017
NOTCH3	Q9UM47-1.2	R1463V	Neutral	0.275
NOTCH3	Q9UM47-1.2	R1463W	Neutral	0.299
NOTCH3	Q9UM47-1.2	R1463Y	Neutral	0.087
NOTCH3	Q9UM47-1.2	E1464A	Neutral	0.225
NOTCH3	Q9UM47-1.2	E1464C	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	E1464D	Neutral	0.003
NOTCH3	Q9UM47-1.2	E1464F	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	E1464G	Pathogenic	0.551
NOTCH3	Q9UM47-1.2	E1464H	Neutral	0.068
NOTCH3	Q9UM47-1.2	E1464I	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	E1464K	Neutral	0.015
NOTCH3	Q9UM47-1.2	E1464L	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	E1464M	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	E1464N	Neutral	0.066
NOTCH3	Q9UM47-1.2	E1464P	Neutral	0.242
NOTCH3	Q9UM47-1.2	E1464Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	E1464R	Neutral	0.06
NOTCH3	Q9UM47-1.2	E1464S	Neutral	0.061
NOTCH3	Q9UM47-1.2	E1464T	Neutral	0.243
NOTCH3	Q9UM47-1.2	E1464V	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	E1464W	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	E1464Y	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	R1465A	Neutral	0.039
NOTCH3	Q9UM47-1.2	R1465C	Neutral	0.479
NOTCH3	Q9UM47-1.2	R1465D	Neutral	0.169
NOTCH3	Q9UM47-1.2	R1465E	Neutral	0.01
NOTCH3	Q9UM47-1.2	R1465F	Pathogenic	0.528
NOTCH3	Q9UM47-1.2	R1465G	Neutral	0.147
NOTCH3	Q9UM47-1.2	R1465H	Neutral	0.011
NOTCH3	Q9UM47-1.2	R1465I	Pathogenic	0.517
NOTCH3	Q9UM47-1.2	R1465K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1465L	Neutral	0.19
NOTCH3	Q9UM47-1.2	R1465M	Neutral	0.049
NOTCH3	Q9UM47-1.2	R1465N	Neutral	0.01
NOTCH3	Q9UM47-1.2	R1465P	Neutral	0.17
NOTCH3	Q9UM47-1.2	R1465Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1465S	Neutral	0.04
NOTCH3	Q9UM47-1.2	R1465T	Neutral	0.043
NOTCH3	Q9UM47-1.2	R1465V	Neutral	0.498
NOTCH3	Q9UM47-1.2	R1465W	Pathogenic	0.527
NOTCH3	Q9UM47-1.2	R1465Y	Neutral	0.2
NOTCH3	Q9UM47-1.2	T1466A	Neutral	0.026
NOTCH3	Q9UM47-1.2	T1466C	Neutral	0.117
NOTCH3	Q9UM47-1.2	T1466D	Neutral	0.119
NOTCH3	Q9UM47-1.2	T1466E	Neutral	0.113
NOTCH3	Q9UM47-1.2	T1466F	Neutral	0.346
NOTCH3	Q9UM47-1.2	T1466G	Neutral	0.341
NOTCH3	Q9UM47-1.2	T1466H	Neutral	0.358
NOTCH3	Q9UM47-1.2	T1466I	Neutral	0.108
NOTCH3	Q9UM47-1.2	T1466K	Neutral	0.104
NOTCH3	Q9UM47-1.2	T1466L	Neutral	0.108
NOTCH3	Q9UM47-1.2	T1466M	Neutral	0.108
NOTCH3	Q9UM47-1.2	T1466N	Neutral	0.029
NOTCH3	Q9UM47-1.2	T1466P	Neutral	0.118
NOTCH3	Q9UM47-1.2	T1466Q	Neutral	0.111
NOTCH3	Q9UM47-1.2	T1466R	Neutral	0.099
NOTCH3	Q9UM47-1.2	T1466S	Neutral	0.006
NOTCH3	Q9UM47-1.2	T1466V	Neutral	0.028
NOTCH3	Q9UM47-1.2	T1466W	Neutral	0.323
NOTCH3	Q9UM47-1.2	T1466Y	Neutral	0.339
NOTCH3	Q9UM47-1.2	C1467A	Neutral	0.488
NOTCH3	Q9UM47-1.2	C1467D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1467E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1467F	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	C1467G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1467H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1467I	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C1467K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1467L	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C1467M	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	C1467N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1467P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1467Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1467R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1467S	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	C1467T	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C1467V	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	C1467W	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	C1467Y	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	N1468A	Pathogenic	0.755
NOTCH3	Q9UM47-1.2	N1468C	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	N1468D	Neutral	0.034
NOTCH3	Q9UM47-1.2	N1468E	Neutral	0.136
NOTCH3	Q9UM47-1.2	N1468F	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	N1468G	Neutral	0.121
NOTCH3	Q9UM47-1.2	N1468H	Neutral	0.032
NOTCH3	Q9UM47-1.2	N1468I	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	N1468K	Neutral	0.125
NOTCH3	Q9UM47-1.2	N1468L	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	N1468M	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	N1468P	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	N1468Q	Neutral	0.134
NOTCH3	Q9UM47-1.2	N1468R	Neutral	0.119
NOTCH3	Q9UM47-1.2	N1468S	Neutral	0.032
NOTCH3	Q9UM47-1.2	N1468T	Neutral	0.141
NOTCH3	Q9UM47-1.2	N1468V	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	N1468W	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	N1468Y	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	P1469A	Neutral	0.336
NOTCH3	Q9UM47-1.2	P1469C	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	P1469D	Neutral	0.358
NOTCH3	Q9UM47-1.2	P1469E	Neutral	0.342
NOTCH3	Q9UM47-1.2	P1469F	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P1469G	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	P1469H	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	P1469I	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	P1469K	Neutral	0.32
NOTCH3	Q9UM47-1.2	P1469L	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	P1469M	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	P1469N	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	P1469Q	Neutral	0.337
NOTCH3	Q9UM47-1.2	P1469R	Pathogenic	0.671
NOTCH3	Q9UM47-1.2	P1469S	Neutral	0.342
NOTCH3	Q9UM47-1.2	P1469T	Neutral	0.354
NOTCH3	Q9UM47-1.2	P1469V	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	P1469W	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	P1469Y	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	V1470A	Neutral	0.01
NOTCH3	Q9UM47-1.2	V1470C	Neutral	0.046
NOTCH3	Q9UM47-1.2	V1470D	Pathogenic	0.51
NOTCH3	Q9UM47-1.2	V1470E	Neutral	0.192
NOTCH3	Q9UM47-1.2	V1470F	Neutral	0.045
NOTCH3	Q9UM47-1.2	V1470G	Neutral	0.467
NOTCH3	Q9UM47-1.2	V1470H	Pathogenic	0.509
NOTCH3	Q9UM47-1.2	V1470I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V1470K	Neutral	0.177
NOTCH3	Q9UM47-1.2	V1470L	Neutral	0.002
NOTCH3	Q9UM47-1.2	V1470M	Neutral	0.002
NOTCH3	Q9UM47-1.2	V1470N	Pathogenic	0.515
NOTCH3	Q9UM47-1.2	V1470P	Neutral	0.184
NOTCH3	Q9UM47-1.2	V1470Q	Neutral	0.189
NOTCH3	Q9UM47-1.2	V1470R	Neutral	0.483
NOTCH3	Q9UM47-1.2	V1470S	Neutral	0.175
NOTCH3	Q9UM47-1.2	V1470T	Neutral	0.011
NOTCH3	Q9UM47-1.2	V1470W	Neutral	0.466
NOTCH3	Q9UM47-1.2	V1470Y	Neutral	0.044
NOTCH3	Q9UM47-1.2	Y1471A	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	Y1471C	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	Y1471D	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	Y1471E	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	Y1471F	Neutral	0.038
NOTCH3	Q9UM47-1.2	Y1471G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	Y1471H	Neutral	0.144
NOTCH3	Q9UM47-1.2	Y1471I	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	Y1471K	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	Y1471L	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	Y1471M	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	Y1471N	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	Y1471P	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	Y1471Q	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	Y1471R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	Y1471S	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	Y1471T	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	Y1471V	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	Y1471W	Neutral	0.144
NOTCH3	Q9UM47-1.2	E1472A	Neutral	0.131
NOTCH3	Q9UM47-1.2	E1472C	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	E1472D	Neutral	0.002
NOTCH3	Q9UM47-1.2	E1472F	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	E1472G	Neutral	0.39
NOTCH3	Q9UM47-1.2	E1472H	Neutral	0.036
NOTCH3	Q9UM47-1.2	E1472I	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	E1472K	Neutral	0.008
NOTCH3	Q9UM47-1.2	E1472L	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	E1472M	Neutral	0.435
NOTCH3	Q9UM47-1.2	E1472N	Neutral	0.036
NOTCH3	Q9UM47-1.2	E1472P	Neutral	0.142
NOTCH3	Q9UM47-1.2	E1472Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	E1472R	Neutral	0.032
NOTCH3	Q9UM47-1.2	E1472S	Neutral	0.033
NOTCH3	Q9UM47-1.2	E1472T	Neutral	0.143
NOTCH3	Q9UM47-1.2	E1472V	Neutral	0.446
NOTCH3	Q9UM47-1.2	E1472W	Pathogenic	0.753
NOTCH3	Q9UM47-1.2	E1472Y	Neutral	0.419
NOTCH3	Q9UM47-1.2	K1473A	Neutral	0.389
NOTCH3	Q9UM47-1.2	K1473C	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	K1473D	Neutral	0.409
NOTCH3	Q9UM47-1.2	K1473E	Neutral	0.035
NOTCH3	Q9UM47-1.2	K1473F	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	K1473G	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	K1473H	Neutral	0.436
NOTCH3	Q9UM47-1.2	K1473I	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	K1473L	Pathogenic	0.785
NOTCH3	Q9UM47-1.2	K1473M	Neutral	0.444
NOTCH3	Q9UM47-1.2	K1473N	Neutral	0.134
NOTCH3	Q9UM47-1.2	K1473P	Neutral	0.411
NOTCH3	Q9UM47-1.2	K1473Q	Neutral	0.035
NOTCH3	Q9UM47-1.2	K1473R	Neutral	0.008
NOTCH3	Q9UM47-1.2	K1473S	Neutral	0.125
NOTCH3	Q9UM47-1.2	K1473T	Neutral	0.413
NOTCH3	Q9UM47-1.2	K1473V	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	K1473W	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	K1473Y	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	Y1474A	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	Y1474C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	Y1474D	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	Y1474E	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	Y1474F	Neutral	0.04
NOTCH3	Q9UM47-1.2	Y1474G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	Y1474H	Neutral	0.151
NOTCH3	Q9UM47-1.2	Y1474I	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	Y1474K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	Y1474L	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	Y1474M	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	Y1474N	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	Y1474P	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	Y1474Q	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	Y1474R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	Y1474S	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	Y1474T	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	Y1474V	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	Y1474W	Neutral	0.152
NOTCH3	Q9UM47-1.2	C1475A	Pathogenic	0.507
NOTCH3	Q9UM47-1.2	C1475D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1475E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1475F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	C1475G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1475H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1475I	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C1475K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1475L	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C1475M	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	C1475N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1475P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1475Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1475R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1475S	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	C1475T	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	C1475V	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	C1475W	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	C1475Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	A1476C	Neutral	0.027
NOTCH3	Q9UM47-1.2	A1476D	Neutral	0.363
NOTCH3	Q9UM47-1.2	A1476E	Neutral	0.105
NOTCH3	Q9UM47-1.2	A1476F	Neutral	0.326
NOTCH3	Q9UM47-1.2	A1476G	Neutral	0.027
NOTCH3	Q9UM47-1.2	A1476H	Neutral	0.338
NOTCH3	Q9UM47-1.2	A1476I	Neutral	0.1
NOTCH3	Q9UM47-1.2	A1476K	Neutral	0.096
NOTCH3	Q9UM47-1.2	A1476L	Neutral	0.1
NOTCH3	Q9UM47-1.2	A1476M	Neutral	0.099
NOTCH3	Q9UM47-1.2	A1476N	Neutral	0.359
NOTCH3	Q9UM47-1.2	A1476P	Neutral	0.111
NOTCH3	Q9UM47-1.2	A1476Q	Neutral	0.102
NOTCH3	Q9UM47-1.2	A1476R	Neutral	0.092
NOTCH3	Q9UM47-1.2	A1476S	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1476T	Neutral	0.026
NOTCH3	Q9UM47-1.2	A1476V	Neutral	0.025
NOTCH3	Q9UM47-1.2	A1476W	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	A1476Y	Neutral	0.319
NOTCH3	Q9UM47-1.2	D1477A	Pathogenic	0.873
NOTCH3	Q9UM47-1.2	D1477C	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	D1477E	Neutral	0.016
NOTCH3	Q9UM47-1.2	D1477F	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	D1477G	Pathogenic	0.583
NOTCH3	Q9UM47-1.2	D1477H	Pathogenic	0.598
NOTCH3	Q9UM47-1.2	D1477I	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	D1477K	Pathogenic	0.581
NOTCH3	Q9UM47-1.2	D1477L	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	D1477M	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	D1477N	Neutral	0.072
NOTCH3	Q9UM47-1.2	D1477P	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	D1477Q	Neutral	0.249
NOTCH3	Q9UM47-1.2	D1477R	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	D1477S	Neutral	0.252
NOTCH3	Q9UM47-1.2	D1477T	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	D1477V	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	D1477W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	D1477Y	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	H1478A	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	H1478C	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	H1478D	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	H1478E	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	H1478F	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	H1478G	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	H1478I	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1478K	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	H1478L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1478M	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	H1478N	Neutral	0.335
NOTCH3	Q9UM47-1.2	H1478P	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	H1478Q	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	H1478R	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	H1478S	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	H1478T	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	H1478V	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1478W	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	H1478Y	Neutral	0.099
NOTCH3	Q9UM47-1.2	F1479A	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	F1479C	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	F1479D	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	F1479E	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	F1479G	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	F1479H	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	F1479I	Neutral	0.44
NOTCH3	Q9UM47-1.2	F1479K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	F1479L	Neutral	0.44
NOTCH3	Q9UM47-1.2	F1479M	Neutral	0.441
NOTCH3	Q9UM47-1.2	F1479N	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	F1479P	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1479Q	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	F1479R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	F1479S	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	F1479T	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	F1479V	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	F1479W	Neutral	0.139
NOTCH3	Q9UM47-1.2	F1479Y	Neutral	0.008
NOTCH3	Q9UM47-1.2	A1480C	Neutral	0.035
NOTCH3	Q9UM47-1.2	A1480D	Neutral	0.423
NOTCH3	Q9UM47-1.2	A1480E	Neutral	0.13
NOTCH3	Q9UM47-1.2	A1480F	Neutral	0.383
NOTCH3	Q9UM47-1.2	A1480G	Neutral	0.035
NOTCH3	Q9UM47-1.2	A1480H	Neutral	0.396
NOTCH3	Q9UM47-1.2	A1480I	Neutral	0.125
NOTCH3	Q9UM47-1.2	A1480K	Neutral	0.12
NOTCH3	Q9UM47-1.2	A1480L	Neutral	0.124
NOTCH3	Q9UM47-1.2	A1480M	Neutral	0.124
NOTCH3	Q9UM47-1.2	A1480N	Neutral	0.418
NOTCH3	Q9UM47-1.2	A1480P	Neutral	0.138
NOTCH3	Q9UM47-1.2	A1480Q	Neutral	0.128
NOTCH3	Q9UM47-1.2	A1480R	Neutral	0.115
NOTCH3	Q9UM47-1.2	A1480S	Neutral	0.008
NOTCH3	Q9UM47-1.2	A1480T	Neutral	0.034
NOTCH3	Q9UM47-1.2	A1480V	Neutral	0.032
NOTCH3	Q9UM47-1.2	A1480W	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	A1480Y	Neutral	0.376
NOTCH3	Q9UM47-1.2	D1481A	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	D1481C	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	D1481E	Neutral	0.016
NOTCH3	Q9UM47-1.2	D1481F	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	D1481G	Pathogenic	0.576
NOTCH3	Q9UM47-1.2	D1481H	Pathogenic	0.592
NOTCH3	Q9UM47-1.2	D1481I	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	D1481K	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	D1481L	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	D1481M	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	D1481N	Neutral	0.07
NOTCH3	Q9UM47-1.2	D1481P	Pathogenic	0.617
NOTCH3	Q9UM47-1.2	D1481Q	Neutral	0.244
NOTCH3	Q9UM47-1.2	D1481R	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	D1481S	Neutral	0.248
NOTCH3	Q9UM47-1.2	D1481T	Pathogenic	0.615
NOTCH3	Q9UM47-1.2	D1481V	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	D1481W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	D1481Y	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	G1482A	Neutral	0.084
NOTCH3	Q9UM47-1.2	G1482C	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	G1482D	Neutral	0.278
NOTCH3	Q9UM47-1.2	G1482E	Pathogenic	0.62
NOTCH3	Q9UM47-1.2	G1482F	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	G1482H	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	G1482I	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	G1482K	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	G1482L	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	G1482M	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	G1482N	Neutral	0.076
NOTCH3	Q9UM47-1.2	G1482P	Pathogenic	0.637
NOTCH3	Q9UM47-1.2	G1482Q	Pathogenic	0.614
NOTCH3	Q9UM47-1.2	G1482R	Pathogenic	0.584
NOTCH3	Q9UM47-1.2	G1482S	Neutral	0.083
NOTCH3	Q9UM47-1.2	G1482T	Pathogenic	0.633
NOTCH3	Q9UM47-1.2	G1482V	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	G1482W	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	G1482Y	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	R1483A	Neutral	0.079
NOTCH3	Q9UM47-1.2	R1483C	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	R1483D	Neutral	0.298
NOTCH3	Q9UM47-1.2	R1483E	Neutral	0.021
NOTCH3	Q9UM47-1.2	R1483F	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	R1483G	Neutral	0.265
NOTCH3	Q9UM47-1.2	R1483H	Neutral	0.022
NOTCH3	Q9UM47-1.2	R1483I	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	R1483K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1483L	Neutral	0.329
NOTCH3	Q9UM47-1.2	R1483M	Neutral	0.097
NOTCH3	Q9UM47-1.2	R1483N	Neutral	0.02
NOTCH3	Q9UM47-1.2	R1483P	Neutral	0.299
NOTCH3	Q9UM47-1.2	R1483Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	R1483S	Neutral	0.08
NOTCH3	Q9UM47-1.2	R1483T	Neutral	0.086
NOTCH3	Q9UM47-1.2	R1483V	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	R1483W	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	R1483Y	Neutral	0.343
NOTCH3	Q9UM47-1.2	C1484A	Pathogenic	0.512
NOTCH3	Q9UM47-1.2	C1484D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1484E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1484F	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	C1484G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1484H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1484I	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C1484K	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1484L	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C1484M	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	C1484N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1484P	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	C1484Q	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1484R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1484S	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	C1484T	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	C1484V	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	C1484W	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	C1484Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	D1485A	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	D1485C	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1485E	Neutral	0.028
NOTCH3	Q9UM47-1.2	D1485F	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	D1485G	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	D1485H	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	D1485I	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D1485K	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	D1485L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1485M	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D1485N	Neutral	0.123
NOTCH3	Q9UM47-1.2	D1485P	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	D1485Q	Neutral	0.373
NOTCH3	Q9UM47-1.2	D1485R	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	D1485S	Neutral	0.378
NOTCH3	Q9UM47-1.2	D1485T	Pathogenic	0.747
NOTCH3	Q9UM47-1.2	D1485V	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D1485W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D1485Y	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	Q1486A	Pathogenic	0.604
NOTCH3	Q9UM47-1.2	Q1486C	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	Q1486D	Neutral	0.269
NOTCH3	Q9UM47-1.2	Q1486E	Neutral	0.019
NOTCH3	Q9UM47-1.2	Q1486F	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	Q1486G	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	Q1486H	Neutral	0.283
NOTCH3	Q9UM47-1.2	Q1486I	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	Q1486K	Neutral	0.075
NOTCH3	Q9UM47-1.2	Q1486L	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	Q1486M	Neutral	0.28
NOTCH3	Q9UM47-1.2	Q1486N	Neutral	0.272
NOTCH3	Q9UM47-1.2	Q1486P	Pathogenic	0.626
NOTCH3	Q9UM47-1.2	Q1486R	Neutral	0.072
NOTCH3	Q9UM47-1.2	Q1486S	Neutral	0.255
NOTCH3	Q9UM47-1.2	Q1486T	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	Q1486V	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	Q1486W	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	Q1486Y	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	G1487A	Neutral	0.169
NOTCH3	Q9UM47-1.2	G1487C	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	G1487D	Neutral	0.459
NOTCH3	Q9UM47-1.2	G1487E	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	G1487F	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	G1487H	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	G1487I	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	G1487K	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	G1487L	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	G1487M	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	G1487N	Neutral	0.154
NOTCH3	Q9UM47-1.2	G1487P	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	G1487Q	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	G1487R	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	G1487S	Neutral	0.166
NOTCH3	Q9UM47-1.2	G1487T	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	G1487V	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	G1487W	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	G1487Y	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	C1488A	Neutral	0.497
NOTCH3	Q9UM47-1.2	C1488D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1488E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1488F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	C1488G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1488H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1488I	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C1488K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1488L	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C1488M	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	C1488N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1488P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1488Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1488R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1488S	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	C1488T	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	C1488V	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C1488W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	C1488Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	N1489A	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	N1489C	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	N1489D	Neutral	0.101
NOTCH3	Q9UM47-1.2	N1489E	Neutral	0.33
NOTCH3	Q9UM47-1.2	N1489F	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	N1489G	Neutral	0.302
NOTCH3	Q9UM47-1.2	N1489H	Neutral	0.095
NOTCH3	Q9UM47-1.2	N1489I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	N1489K	Neutral	0.309
NOTCH3	Q9UM47-1.2	N1489L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	N1489M	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	N1489P	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	N1489Q	Neutral	0.326
NOTCH3	Q9UM47-1.2	N1489R	Neutral	0.298
NOTCH3	Q9UM47-1.2	N1489S	Neutral	0.095
NOTCH3	Q9UM47-1.2	N1489T	Neutral	0.34
NOTCH3	Q9UM47-1.2	N1489V	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	N1489W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	N1489Y	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	T1490A	Neutral	0.023
NOTCH3	Q9UM47-1.2	T1490C	Neutral	0.103
NOTCH3	Q9UM47-1.2	T1490D	Neutral	0.105
NOTCH3	Q9UM47-1.2	T1490E	Neutral	0.1
NOTCH3	Q9UM47-1.2	T1490F	Neutral	0.314
NOTCH3	Q9UM47-1.2	T1490G	Neutral	0.309
NOTCH3	Q9UM47-1.2	T1490H	Neutral	0.326
NOTCH3	Q9UM47-1.2	T1490I	Neutral	0.095
NOTCH3	Q9UM47-1.2	T1490K	Neutral	0.091
NOTCH3	Q9UM47-1.2	T1490L	Neutral	0.095
NOTCH3	Q9UM47-1.2	T1490M	Neutral	0.095
NOTCH3	Q9UM47-1.2	T1490N	Neutral	0.025
NOTCH3	Q9UM47-1.2	T1490P	Neutral	0.104
NOTCH3	Q9UM47-1.2	T1490Q	Neutral	0.097
NOTCH3	Q9UM47-1.2	T1490R	Neutral	0.087
NOTCH3	Q9UM47-1.2	T1490S	Neutral	0.005
NOTCH3	Q9UM47-1.2	T1490V	Neutral	0.024
NOTCH3	Q9UM47-1.2	T1490W	Neutral	0.292
NOTCH3	Q9UM47-1.2	T1490Y	Neutral	0.307
NOTCH3	Q9UM47-1.2	E1491A	Neutral	0.328
NOTCH3	Q9UM47-1.2	E1491C	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	E1491D	Neutral	0.006
NOTCH3	Q9UM47-1.2	E1491F	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	E1491G	Pathogenic	0.673
NOTCH3	Q9UM47-1.2	E1491H	Neutral	0.109
NOTCH3	Q9UM47-1.2	E1491I	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	E1491K	Neutral	0.024
NOTCH3	Q9UM47-1.2	E1491L	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	E1491M	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	E1491N	Neutral	0.106
NOTCH3	Q9UM47-1.2	E1491P	Neutral	0.349
NOTCH3	Q9UM47-1.2	E1491Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	E1491R	Neutral	0.098
NOTCH3	Q9UM47-1.2	E1491S	Neutral	0.099
NOTCH3	Q9UM47-1.2	E1491T	Neutral	0.351
NOTCH3	Q9UM47-1.2	E1491V	Pathogenic	0.722
NOTCH3	Q9UM47-1.2	E1491W	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	E1491Y	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	E1492A	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	E1492C	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	E1492D	Neutral	0.029
NOTCH3	Q9UM47-1.2	E1492F	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	E1492G	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	E1492H	Neutral	0.396
NOTCH3	Q9UM47-1.2	E1492I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	E1492K	Neutral	0.118
NOTCH3	Q9UM47-1.2	E1492L	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	E1492M	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	E1492N	Neutral	0.39
NOTCH3	Q9UM47-1.2	E1492P	Pathogenic	0.742
NOTCH3	Q9UM47-1.2	E1492Q	Neutral	0.031
NOTCH3	Q9UM47-1.2	E1492R	Neutral	0.368
NOTCH3	Q9UM47-1.2	E1492S	Neutral	0.371
NOTCH3	Q9UM47-1.2	E1492T	Pathogenic	0.744
NOTCH3	Q9UM47-1.2	E1492V	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	E1492W	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	E1492Y	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	C1493A	Pathogenic	0.501
NOTCH3	Q9UM47-1.2	C1493D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1493E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1493F	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	C1493G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1493H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1493I	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C1493K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1493L	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	C1493M	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	C1493N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1493P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1493Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1493R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1493S	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	C1493T	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	C1493V	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	C1493W	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	C1493Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	G1494A	Neutral	0.036
NOTCH3	Q9UM47-1.2	G1494C	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	G1494D	Neutral	0.134
NOTCH3	Q9UM47-1.2	G1494E	Neutral	0.395
NOTCH3	Q9UM47-1.2	G1494F	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	G1494H	Neutral	0.386
NOTCH3	Q9UM47-1.2	G1494I	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	G1494K	Neutral	0.372
NOTCH3	Q9UM47-1.2	G1494L	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	G1494M	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	G1494N	Neutral	0.032
NOTCH3	Q9UM47-1.2	G1494P	Neutral	0.413
NOTCH3	Q9UM47-1.2	G1494Q	Neutral	0.39
NOTCH3	Q9UM47-1.2	G1494R	Neutral	0.361
NOTCH3	Q9UM47-1.2	G1494S	Neutral	0.035
NOTCH3	Q9UM47-1.2	G1494T	Neutral	0.409
NOTCH3	Q9UM47-1.2	G1494V	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	G1494W	Neutral	0.35
NOTCH3	Q9UM47-1.2	G1494Y	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	W1495A	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1495C	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1495D	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1495E	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1495F	Pathogenic	0.861
NOTCH3	Q9UM47-1.2	W1495G	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1495H	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1495I	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1495K	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1495L	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1495M	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	W1495N	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1495P	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1495Q	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1495R	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1495S	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1495T	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1495V	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1495Y	Pathogenic	0.583
NOTCH3	Q9UM47-1.2	D1496A	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	D1496C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D1496E	Neutral	0.033
NOTCH3	Q9UM47-1.2	D1496F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1496G	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	D1496H	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	D1496I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1496K	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	D1496L	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	D1496M	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1496N	Neutral	0.142
NOTCH3	Q9UM47-1.2	D1496P	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	D1496Q	Neutral	0.413
NOTCH3	Q9UM47-1.2	D1496R	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	D1496S	Neutral	0.418
NOTCH3	Q9UM47-1.2	D1496T	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	D1496V	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D1496W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1496Y	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	G1497A	Neutral	0.244
NOTCH3	Q9UM47-1.2	G1497C	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	G1497D	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	G1497E	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	G1497F	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1497H	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G1497I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1497K	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	G1497L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1497M	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G1497N	Neutral	0.224
NOTCH3	Q9UM47-1.2	G1497P	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	G1497Q	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G1497R	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	G1497S	Neutral	0.239
NOTCH3	Q9UM47-1.2	G1497T	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	G1497V	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G1497W	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G1497Y	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	L1498A	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	L1498C	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	L1498D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1498E	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1498F	Neutral	0.366
NOTCH3	Q9UM47-1.2	L1498G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1498H	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1498I	Neutral	0.028
NOTCH3	Q9UM47-1.2	L1498K	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	L1498M	Neutral	0.028
NOTCH3	Q9UM47-1.2	L1498N	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L1498P	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	L1498Q	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	L1498R	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	L1498S	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	L1498T	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	L1498V	Neutral	0.11
NOTCH3	Q9UM47-1.2	L1498W	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	L1498Y	Pathogenic	0.72
NOTCH3	Q9UM47-1.2	D1499A	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	D1499C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D1499E	Neutral	0.033
NOTCH3	Q9UM47-1.2	D1499F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1499G	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	D1499H	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	D1499I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1499K	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	D1499L	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	D1499M	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1499N	Neutral	0.142
NOTCH3	Q9UM47-1.2	D1499P	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	D1499Q	Neutral	0.413
NOTCH3	Q9UM47-1.2	D1499R	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	D1499S	Neutral	0.418
NOTCH3	Q9UM47-1.2	D1499T	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	D1499V	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D1499W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1499Y	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	C1500A	Neutral	0.491
NOTCH3	Q9UM47-1.2	C1500D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1500E	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	C1500F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	C1500G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1500H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1500I	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C1500K	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	C1500L	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	C1500M	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	C1500N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1500P	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	C1500Q	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	C1500R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	C1500S	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	C1500T	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	C1500V	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	C1500W	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	C1500Y	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	A1501C	Neutral	0.183
NOTCH3	Q9UM47-1.2	A1501D	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	A1501E	Neutral	0.482
NOTCH3	Q9UM47-1.2	A1501F	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	A1501G	Neutral	0.182
NOTCH3	Q9UM47-1.2	A1501H	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	A1501I	Neutral	0.469
NOTCH3	Q9UM47-1.2	A1501K	Neutral	0.458
NOTCH3	Q9UM47-1.2	A1501L	Neutral	0.469
NOTCH3	Q9UM47-1.2	A1501M	Neutral	0.468
NOTCH3	Q9UM47-1.2	A1501N	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	A1501P	Neutral	0.5
NOTCH3	Q9UM47-1.2	A1501Q	Neutral	0.477
NOTCH3	Q9UM47-1.2	A1501R	Neutral	0.446
NOTCH3	Q9UM47-1.2	A1501S	Neutral	0.049
NOTCH3	Q9UM47-1.2	A1501T	Neutral	0.178
NOTCH3	Q9UM47-1.2	A1501V	Neutral	0.172
NOTCH3	Q9UM47-1.2	A1501W	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	A1501Y	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	S1502A	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1502C	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1502D	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1502E	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1502F	Neutral	0.012
NOTCH3	Q9UM47-1.2	S1502G	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1502H	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1502I	Neutral	0.013
NOTCH3	Q9UM47-1.2	S1502K	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1502L	Neutral	0.013
NOTCH3	Q9UM47-1.2	S1502M	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1502N	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1502P	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1502Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1502R	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1502T	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1502V	Neutral	0.014
NOTCH3	Q9UM47-1.2	S1502W	Neutral	0.049
NOTCH3	Q9UM47-1.2	S1502Y	Neutral	0.012
NOTCH3	Q9UM47-1.2	E1503A	Neutral	0.027
NOTCH3	Q9UM47-1.2	E1503C	Pathogenic	0.742
NOTCH3	Q9UM47-1.2	E1503D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1503F	Neutral	0.387
NOTCH3	Q9UM47-1.2	E1503G	Neutral	0.106
NOTCH3	Q9UM47-1.2	E1503H	Neutral	0.007
NOTCH3	Q9UM47-1.2	E1503I	Neutral	0.397
NOTCH3	Q9UM47-1.2	E1503K	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1503L	Neutral	0.396
NOTCH3	Q9UM47-1.2	E1503M	Neutral	0.126
NOTCH3	Q9UM47-1.2	E1503N	Neutral	0.007
NOTCH3	Q9UM47-1.2	E1503P	Neutral	0.03
NOTCH3	Q9UM47-1.2	E1503Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1503R	Neutral	0.006
NOTCH3	Q9UM47-1.2	E1503S	Neutral	0.006
NOTCH3	Q9UM47-1.2	E1503T	Neutral	0.03
NOTCH3	Q9UM47-1.2	E1503V	Neutral	0.13
NOTCH3	Q9UM47-1.2	E1503W	Neutral	0.362
NOTCH3	Q9UM47-1.2	E1503Y	Neutral	0.118
NOTCH3	Q9UM47-1.2	V1504A	Neutral	0.023
NOTCH3	Q9UM47-1.2	V1504C	Neutral	0.103
NOTCH3	Q9UM47-1.2	V1504D	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	V1504E	Neutral	0.359
NOTCH3	Q9UM47-1.2	V1504F	Neutral	0.099
NOTCH3	Q9UM47-1.2	V1504G	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	V1504H	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	V1504I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V1504K	Neutral	0.337
NOTCH3	Q9UM47-1.2	V1504L	Neutral	0.006
NOTCH3	Q9UM47-1.2	V1504M	Neutral	0.005
NOTCH3	Q9UM47-1.2	V1504N	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	V1504P	Neutral	0.347
NOTCH3	Q9UM47-1.2	V1504Q	Neutral	0.354
NOTCH3	Q9UM47-1.2	V1504R	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	V1504S	Neutral	0.334
NOTCH3	Q9UM47-1.2	V1504T	Neutral	0.025
NOTCH3	Q9UM47-1.2	V1504W	Pathogenic	0.673
NOTCH3	Q9UM47-1.2	V1504Y	Neutral	0.097
NOTCH3	Q9UM47-1.2	P1505A	Pathogenic	0.558
NOTCH3	Q9UM47-1.2	P1505C	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	P1505D	Pathogenic	0.581
NOTCH3	Q9UM47-1.2	P1505E	Pathogenic	0.564
NOTCH3	Q9UM47-1.2	P1505F	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	P1505G	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	P1505H	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	P1505I	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	P1505K	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	P1505L	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	P1505M	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	P1505N	Pathogenic	0.861
NOTCH3	Q9UM47-1.2	P1505Q	Pathogenic	0.558
NOTCH3	Q9UM47-1.2	P1505R	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	P1505S	Pathogenic	0.565
NOTCH3	Q9UM47-1.2	P1505T	Pathogenic	0.577
NOTCH3	Q9UM47-1.2	P1505V	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	P1505W	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	P1505Y	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	A1506C	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1506D	Neutral	0.188
NOTCH3	Q9UM47-1.2	A1506E	Neutral	0.045
NOTCH3	Q9UM47-1.2	A1506F	Neutral	0.164
NOTCH3	Q9UM47-1.2	A1506G	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1506H	Neutral	0.171
NOTCH3	Q9UM47-1.2	A1506I	Neutral	0.043
NOTCH3	Q9UM47-1.2	A1506K	Neutral	0.041
NOTCH3	Q9UM47-1.2	A1506L	Neutral	0.043
NOTCH3	Q9UM47-1.2	A1506M	Neutral	0.043
NOTCH3	Q9UM47-1.2	A1506N	Neutral	0.185
NOTCH3	Q9UM47-1.2	A1506P	Neutral	0.048
NOTCH3	Q9UM47-1.2	A1506Q	Neutral	0.044
NOTCH3	Q9UM47-1.2	A1506R	Neutral	0.039
NOTCH3	Q9UM47-1.2	A1506S	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1506T	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1506V	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1506W	Neutral	0.446
NOTCH3	Q9UM47-1.2	A1506Y	Neutral	0.16
NOTCH3	Q9UM47-1.2	L1507A	Neutral	0.009
NOTCH3	Q9UM47-1.2	L1507C	Neutral	0.01
NOTCH3	Q9UM47-1.2	L1507D	Neutral	0.494
NOTCH3	Q9UM47-1.2	L1507E	Neutral	0.187
NOTCH3	Q9UM47-1.2	L1507F	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1507G	Neutral	0.451
NOTCH3	Q9UM47-1.2	L1507H	Neutral	0.191
NOTCH3	Q9UM47-1.2	L1507I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1507K	Neutral	0.049
NOTCH3	Q9UM47-1.2	L1507M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1507N	Neutral	0.179
NOTCH3	Q9UM47-1.2	L1507P	Neutral	0.174
NOTCH3	Q9UM47-1.2	L1507Q	Neutral	0.049
NOTCH3	Q9UM47-1.2	L1507R	Neutral	0.047
NOTCH3	Q9UM47-1.2	L1507S	Neutral	0.042
NOTCH3	Q9UM47-1.2	L1507T	Neutral	0.01
NOTCH3	Q9UM47-1.2	L1507V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1507W	Neutral	0.043
NOTCH3	Q9UM47-1.2	L1507Y	Neutral	0.011
NOTCH3	Q9UM47-1.2	L1508A	Pathogenic	0.565
NOTCH3	Q9UM47-1.2	L1508C	Pathogenic	0.581
NOTCH3	Q9UM47-1.2	L1508D	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	L1508E	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	L1508F	Neutral	0.252
NOTCH3	Q9UM47-1.2	L1508G	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	L1508H	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	L1508I	Neutral	0.017
NOTCH3	Q9UM47-1.2	L1508K	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	L1508M	Neutral	0.017
NOTCH3	Q9UM47-1.2	L1508N	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	L1508P	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	L1508Q	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	L1508R	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	L1508S	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	L1508T	Pathogenic	0.589
NOTCH3	Q9UM47-1.2	L1508V	Neutral	0.067
NOTCH3	Q9UM47-1.2	L1508W	Pathogenic	0.863
NOTCH3	Q9UM47-1.2	L1508Y	Pathogenic	0.601
NOTCH3	Q9UM47-1.2	A1509C	Neutral	0.329
NOTCH3	Q9UM47-1.2	A1509D	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	A1509E	Pathogenic	0.672
NOTCH3	Q9UM47-1.2	A1509F	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	A1509G	Neutral	0.328
NOTCH3	Q9UM47-1.2	A1509H	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	A1509I	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	A1509K	Pathogenic	0.65
NOTCH3	Q9UM47-1.2	A1509L	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	A1509M	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	A1509N	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	A1509P	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	A1509Q	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	A1509R	Pathogenic	0.638
NOTCH3	Q9UM47-1.2	A1509S	Neutral	0.101
NOTCH3	Q9UM47-1.2	A1509T	Neutral	0.322
NOTCH3	Q9UM47-1.2	A1509V	Neutral	0.313
NOTCH3	Q9UM47-1.2	A1509W	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	A1509Y	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	R1510A	Neutral	0.027
NOTCH3	Q9UM47-1.2	R1510C	Neutral	0.381
NOTCH3	Q9UM47-1.2	R1510D	Neutral	0.12
NOTCH3	Q9UM47-1.2	R1510E	Neutral	0.007
NOTCH3	Q9UM47-1.2	R1510F	Neutral	0.428
NOTCH3	Q9UM47-1.2	R1510G	Neutral	0.104
NOTCH3	Q9UM47-1.2	R1510H	Neutral	0.007
NOTCH3	Q9UM47-1.2	R1510I	Neutral	0.418
NOTCH3	Q9UM47-1.2	R1510K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R1510L	Neutral	0.136
NOTCH3	Q9UM47-1.2	R1510M	Neutral	0.033
NOTCH3	Q9UM47-1.2	R1510N	Neutral	0.007
NOTCH3	Q9UM47-1.2	R1510P	Neutral	0.12
NOTCH3	Q9UM47-1.2	R1510Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1510S	Neutral	0.027
NOTCH3	Q9UM47-1.2	R1510T	Neutral	0.029
NOTCH3	Q9UM47-1.2	R1510V	Neutral	0.399
NOTCH3	Q9UM47-1.2	R1510W	Neutral	0.427
NOTCH3	Q9UM47-1.2	R1510Y	Neutral	0.143
NOTCH3	Q9UM47-1.2	G1511A	Neutral	0.206
NOTCH3	Q9UM47-1.2	G1511C	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G1511D	Pathogenic	0.519
NOTCH3	Q9UM47-1.2	G1511E	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	G1511F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	G1511H	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	G1511I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G1511K	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	G1511L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G1511M	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	G1511N	Neutral	0.189
NOTCH3	Q9UM47-1.2	G1511P	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	G1511Q	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	G1511R	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	G1511S	Neutral	0.202
NOTCH3	Q9UM47-1.2	G1511T	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G1511V	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G1511W	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	G1511Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	V1512A	Neutral	0.018
NOTCH3	Q9UM47-1.2	V1512C	Neutral	0.081
NOTCH3	Q9UM47-1.2	V1512D	Pathogenic	0.654
NOTCH3	Q9UM47-1.2	V1512E	Neutral	0.301
NOTCH3	Q9UM47-1.2	V1512F	Neutral	0.078
NOTCH3	Q9UM47-1.2	V1512G	Pathogenic	0.614
NOTCH3	Q9UM47-1.2	V1512H	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	V1512I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V1512K	Neutral	0.281
NOTCH3	Q9UM47-1.2	V1512L	Neutral	0.004
NOTCH3	Q9UM47-1.2	V1512M	Neutral	0.004
NOTCH3	Q9UM47-1.2	V1512N	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	V1512P	Neutral	0.29
NOTCH3	Q9UM47-1.2	V1512Q	Neutral	0.296
NOTCH3	Q9UM47-1.2	V1512R	Pathogenic	0.628
NOTCH3	Q9UM47-1.2	V1512S	Neutral	0.278
NOTCH3	Q9UM47-1.2	V1512T	Neutral	0.02
NOTCH3	Q9UM47-1.2	V1512W	Pathogenic	0.613
NOTCH3	Q9UM47-1.2	V1512Y	Neutral	0.076
NOTCH3	Q9UM47-1.2	L1513A	Pathogenic	0.551
NOTCH3	Q9UM47-1.2	L1513C	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	L1513D	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	L1513E	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	L1513F	Neutral	0.241
NOTCH3	Q9UM47-1.2	L1513G	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	L1513H	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	L1513I	Neutral	0.016
NOTCH3	Q9UM47-1.2	L1513K	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	L1513M	Neutral	0.016
NOTCH3	Q9UM47-1.2	L1513N	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	L1513P	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	L1513Q	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	L1513R	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	L1513S	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	L1513T	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	L1513V	Neutral	0.064
NOTCH3	Q9UM47-1.2	L1513W	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	L1513Y	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	V1514A	Neutral	0.272
NOTCH3	Q9UM47-1.2	V1514C	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	V1514D	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	V1514E	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	V1514F	Pathogenic	0.636
NOTCH3	Q9UM47-1.2	V1514G	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	V1514H	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	V1514I	Neutral	0.004
NOTCH3	Q9UM47-1.2	V1514K	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	V1514L	Neutral	0.081
NOTCH3	Q9UM47-1.2	V1514M	Neutral	0.081
NOTCH3	Q9UM47-1.2	V1514N	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	V1514P	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	V1514Q	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	V1514R	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	V1514S	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	V1514T	Neutral	0.292
NOTCH3	Q9UM47-1.2	V1514W	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	V1514Y	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	L1515A	Neutral	0.113
NOTCH3	Q9UM47-1.2	L1515C	Neutral	0.12
NOTCH3	Q9UM47-1.2	L1515D	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	L1515E	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	L1515F	Neutral	0.032
NOTCH3	Q9UM47-1.2	L1515G	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	L1515H	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	L1515I	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1515K	Neutral	0.411
NOTCH3	Q9UM47-1.2	L1515M	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1515N	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	L1515P	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	L1515Q	Neutral	0.41
NOTCH3	Q9UM47-1.2	L1515R	Neutral	0.399
NOTCH3	Q9UM47-1.2	L1515S	Neutral	0.372
NOTCH3	Q9UM47-1.2	L1515T	Neutral	0.123
NOTCH3	Q9UM47-1.2	L1515V	Neutral	0.007
NOTCH3	Q9UM47-1.2	L1515W	Neutral	0.381
NOTCH3	Q9UM47-1.2	L1515Y	Neutral	0.128
NOTCH3	Q9UM47-1.2	T1516A	Neutral	0.016
NOTCH3	Q9UM47-1.2	T1516C	Neutral	0.075
NOTCH3	Q9UM47-1.2	T1516D	Neutral	0.077
NOTCH3	Q9UM47-1.2	T1516E	Neutral	0.073
NOTCH3	Q9UM47-1.2	T1516F	Neutral	0.246
NOTCH3	Q9UM47-1.2	T1516G	Neutral	0.242
NOTCH3	Q9UM47-1.2	T1516H	Neutral	0.256
NOTCH3	Q9UM47-1.2	T1516I	Neutral	0.07
NOTCH3	Q9UM47-1.2	T1516K	Neutral	0.067
NOTCH3	Q9UM47-1.2	T1516L	Neutral	0.069
NOTCH3	Q9UM47-1.2	T1516M	Neutral	0.069
NOTCH3	Q9UM47-1.2	T1516N	Neutral	0.018
NOTCH3	Q9UM47-1.2	T1516P	Neutral	0.076
NOTCH3	Q9UM47-1.2	T1516Q	Neutral	0.071
NOTCH3	Q9UM47-1.2	T1516R	Neutral	0.064
NOTCH3	Q9UM47-1.2	T1516S	Neutral	0.004
NOTCH3	Q9UM47-1.2	T1516V	Neutral	0.017
NOTCH3	Q9UM47-1.2	T1516W	Neutral	0.227
NOTCH3	Q9UM47-1.2	T1516Y	Neutral	0.24
NOTCH3	Q9UM47-1.2	V1517A	Neutral	0.421
NOTCH3	Q9UM47-1.2	V1517C	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	V1517D	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	V1517E	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	V1517F	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	V1517G	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	V1517H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	V1517I	Neutral	0.008
NOTCH3	Q9UM47-1.2	V1517K	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	V1517L	Neutral	0.146
NOTCH3	Q9UM47-1.2	V1517M	Neutral	0.146
NOTCH3	Q9UM47-1.2	V1517N	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	V1517P	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	V1517Q	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	V1517R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	V1517S	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	V1517T	Neutral	0.446
NOTCH3	Q9UM47-1.2	V1517W	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	V1517Y	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	L1518A	Neutral	0.444
NOTCH3	Q9UM47-1.2	L1518C	Neutral	0.461
NOTCH3	Q9UM47-1.2	L1518D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	L1518E	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	L1518F	Neutral	0.172
NOTCH3	Q9UM47-1.2	L1518G	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	L1518H	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	L1518I	Neutral	0.01
NOTCH3	Q9UM47-1.2	L1518K	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	L1518M	Neutral	0.01
NOTCH3	Q9UM47-1.2	L1518N	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	L1518P	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	L1518Q	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	L1518R	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	L1518S	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	L1518T	Neutral	0.469
NOTCH3	Q9UM47-1.2	L1518V	Neutral	0.042
NOTCH3	Q9UM47-1.2	L1518W	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	L1518Y	Neutral	0.481
NOTCH3	Q9UM47-1.2	L1519A	Neutral	0.091
NOTCH3	Q9UM47-1.2	L1519C	Neutral	0.097
NOTCH3	Q9UM47-1.2	L1519D	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	L1519E	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	L1519F	Neutral	0.025
NOTCH3	Q9UM47-1.2	L1519G	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	L1519H	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	L1519I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1519K	Neutral	0.356
NOTCH3	Q9UM47-1.2	L1519M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1519N	Pathogenic	0.701
NOTCH3	Q9UM47-1.2	L1519P	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	L1519Q	Neutral	0.355
NOTCH3	Q9UM47-1.2	L1519R	Neutral	0.344
NOTCH3	Q9UM47-1.2	L1519S	Neutral	0.32
NOTCH3	Q9UM47-1.2	L1519T	Neutral	0.1
NOTCH3	Q9UM47-1.2	L1519V	Neutral	0.006
NOTCH3	Q9UM47-1.2	L1519W	Neutral	0.328
NOTCH3	Q9UM47-1.2	L1519Y	Neutral	0.104
NOTCH3	Q9UM47-1.2	P1520A	Neutral	0.238
NOTCH3	Q9UM47-1.2	P1520C	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	P1520D	Neutral	0.256
NOTCH3	Q9UM47-1.2	P1520E	Neutral	0.242
NOTCH3	Q9UM47-1.2	P1520F	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	P1520G	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	P1520H	Pathogenic	0.583
NOTCH3	Q9UM47-1.2	P1520I	Pathogenic	0.862
NOTCH3	Q9UM47-1.2	P1520K	Neutral	0.225
NOTCH3	Q9UM47-1.2	P1520L	Pathogenic	0.862
NOTCH3	Q9UM47-1.2	P1520M	Pathogenic	0.577
NOTCH3	Q9UM47-1.2	P1520N	Pathogenic	0.605
NOTCH3	Q9UM47-1.2	P1520Q	Neutral	0.238
NOTCH3	Q9UM47-1.2	P1520R	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	P1520S	Neutral	0.243
NOTCH3	Q9UM47-1.2	P1520T	Neutral	0.253
NOTCH3	Q9UM47-1.2	P1520V	Pathogenic	0.595
NOTCH3	Q9UM47-1.2	P1520W	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	P1520Y	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	P1521A	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	P1521C	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	P1521D	Pathogenic	0.571
NOTCH3	Q9UM47-1.2	P1521E	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	P1521F	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	P1521G	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	P1521H	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	P1521I	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	P1521K	Pathogenic	0.529
NOTCH3	Q9UM47-1.2	P1521L	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	P1521M	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	P1521N	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	P1521Q	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	P1521R	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	P1521S	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	P1521T	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	P1521V	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	P1521W	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	P1521Y	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	E1522A	Neutral	0.357
NOTCH3	Q9UM47-1.2	E1522C	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	E1522D	Neutral	0.006
NOTCH3	Q9UM47-1.2	E1522F	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	E1522G	Pathogenic	0.701
NOTCH3	Q9UM47-1.2	E1522H	Neutral	0.121
NOTCH3	Q9UM47-1.2	E1522I	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	E1522K	Neutral	0.028
NOTCH3	Q9UM47-1.2	E1522L	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	E1522M	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	E1522N	Neutral	0.119
NOTCH3	Q9UM47-1.2	E1522P	Neutral	0.378
NOTCH3	Q9UM47-1.2	E1522Q	Neutral	0.007
NOTCH3	Q9UM47-1.2	E1522R	Neutral	0.109
NOTCH3	Q9UM47-1.2	E1522S	Neutral	0.111
NOTCH3	Q9UM47-1.2	E1522T	Neutral	0.38
NOTCH3	Q9UM47-1.2	E1522V	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	E1522W	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	E1522Y	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	E1523A	Neutral	0.125
NOTCH3	Q9UM47-1.2	E1523C	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	E1523D	Neutral	0.002
NOTCH3	Q9UM47-1.2	E1523F	Pathogenic	0.761
NOTCH3	Q9UM47-1.2	E1523G	Neutral	0.376
NOTCH3	Q9UM47-1.2	E1523H	Neutral	0.034
NOTCH3	Q9UM47-1.2	E1523I	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	E1523K	Neutral	0.007
NOTCH3	Q9UM47-1.2	E1523L	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	E1523M	Neutral	0.421
NOTCH3	Q9UM47-1.2	E1523N	Neutral	0.034
NOTCH3	Q9UM47-1.2	E1523P	Neutral	0.136
NOTCH3	Q9UM47-1.2	E1523Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	E1523R	Neutral	0.031
NOTCH3	Q9UM47-1.2	E1523S	Neutral	0.031
NOTCH3	Q9UM47-1.2	E1523T	Neutral	0.136
NOTCH3	Q9UM47-1.2	E1523V	Neutral	0.432
NOTCH3	Q9UM47-1.2	E1523W	Pathogenic	0.742
NOTCH3	Q9UM47-1.2	E1523Y	Neutral	0.405
NOTCH3	Q9UM47-1.2	L1524A	Pathogenic	0.584
NOTCH3	Q9UM47-1.2	L1524C	Pathogenic	0.601
NOTCH3	Q9UM47-1.2	L1524D	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	L1524E	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	L1524F	Neutral	0.267
NOTCH3	Q9UM47-1.2	L1524G	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	L1524H	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	L1524I	Neutral	0.018
NOTCH3	Q9UM47-1.2	L1524K	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	L1524M	Neutral	0.018
NOTCH3	Q9UM47-1.2	L1524N	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	L1524P	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	L1524Q	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	L1524R	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	L1524S	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	L1524T	Pathogenic	0.608
NOTCH3	Q9UM47-1.2	L1524V	Neutral	0.072
NOTCH3	Q9UM47-1.2	L1524W	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	L1524Y	Pathogenic	0.62
NOTCH3	Q9UM47-1.2	L1525A	Neutral	0.241
NOTCH3	Q9UM47-1.2	L1525C	Neutral	0.254
NOTCH3	Q9UM47-1.2	L1525D	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	L1525E	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	L1525F	Neutral	0.076
NOTCH3	Q9UM47-1.2	L1525G	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	L1525H	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	L1525I	Neutral	0.004
NOTCH3	Q9UM47-1.2	L1525K	Pathogenic	0.636
NOTCH3	Q9UM47-1.2	L1525M	Neutral	0.004
NOTCH3	Q9UM47-1.2	L1525N	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	L1525P	Pathogenic	0.878
NOTCH3	Q9UM47-1.2	L1525Q	Pathogenic	0.635
NOTCH3	Q9UM47-1.2	L1525R	Pathogenic	0.624
NOTCH3	Q9UM47-1.2	L1525S	Pathogenic	0.598
NOTCH3	Q9UM47-1.2	L1525T	Neutral	0.26
NOTCH3	Q9UM47-1.2	L1525V	Neutral	0.017
NOTCH3	Q9UM47-1.2	L1525W	Pathogenic	0.606
NOTCH3	Q9UM47-1.2	L1525Y	Neutral	0.269
NOTCH3	Q9UM47-1.2	R1526A	Neutral	0.05
NOTCH3	Q9UM47-1.2	R1526C	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	R1526D	Neutral	0.206
NOTCH3	Q9UM47-1.2	R1526E	Neutral	0.013
NOTCH3	Q9UM47-1.2	R1526F	Pathogenic	0.589
NOTCH3	Q9UM47-1.2	R1526G	Neutral	0.181
NOTCH3	Q9UM47-1.2	R1526H	Neutral	0.014
NOTCH3	Q9UM47-1.2	R1526I	Pathogenic	0.578
NOTCH3	Q9UM47-1.2	R1526K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1526L	Neutral	0.231
NOTCH3	Q9UM47-1.2	R1526M	Neutral	0.062
NOTCH3	Q9UM47-1.2	R1526N	Neutral	0.013
NOTCH3	Q9UM47-1.2	R1526P	Neutral	0.207
NOTCH3	Q9UM47-1.2	R1526Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R1526S	Neutral	0.051
NOTCH3	Q9UM47-1.2	R1526T	Neutral	0.055
NOTCH3	Q9UM47-1.2	R1526V	Pathogenic	0.559
NOTCH3	Q9UM47-1.2	R1526W	Pathogenic	0.588
NOTCH3	Q9UM47-1.2	R1526Y	Neutral	0.242
NOTCH3	Q9UM47-1.2	S1527A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1527C	Neutral	0.023
NOTCH3	Q9UM47-1.2	S1527D	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1527E	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1527F	Neutral	0.08
NOTCH3	Q9UM47-1.2	S1527G	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1527H	Neutral	0.02
NOTCH3	Q9UM47-1.2	S1527I	Neutral	0.084
NOTCH3	Q9UM47-1.2	S1527K	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1527L	Neutral	0.083
NOTCH3	Q9UM47-1.2	S1527M	Neutral	0.02
NOTCH3	Q9UM47-1.2	S1527N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1527P	Neutral	0.022
NOTCH3	Q9UM47-1.2	S1527Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1527R	Neutral	0.018
NOTCH3	Q9UM47-1.2	S1527T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1527V	Neutral	0.089
NOTCH3	Q9UM47-1.2	S1527W	Neutral	0.264
NOTCH3	Q9UM47-1.2	S1527Y	Neutral	0.078
NOTCH3	Q9UM47-1.2	S1528A	Neutral	0.012
NOTCH3	Q9UM47-1.2	S1528C	Neutral	0.204
NOTCH3	Q9UM47-1.2	S1528D	Neutral	0.052
NOTCH3	Q9UM47-1.2	S1528E	Neutral	0.049
NOTCH3	Q9UM47-1.2	S1528F	Neutral	0.493
NOTCH3	Q9UM47-1.2	S1528G	Neutral	0.051
NOTCH3	Q9UM47-1.2	S1528H	Neutral	0.183
NOTCH3	Q9UM47-1.2	S1528I	Pathogenic	0.503
NOTCH3	Q9UM47-1.2	S1528K	Neutral	0.044
NOTCH3	Q9UM47-1.2	S1528L	Pathogenic	0.503
NOTCH3	Q9UM47-1.2	S1528M	Neutral	0.181
NOTCH3	Q9UM47-1.2	S1528N	Neutral	0.012
NOTCH3	Q9UM47-1.2	S1528P	Neutral	0.201
NOTCH3	Q9UM47-1.2	S1528Q	Neutral	0.048
NOTCH3	Q9UM47-1.2	S1528R	Neutral	0.168
NOTCH3	Q9UM47-1.2	S1528T	Neutral	0.012
NOTCH3	Q9UM47-1.2	S1528V	Pathogenic	0.52
NOTCH3	Q9UM47-1.2	S1528W	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	S1528Y	Neutral	0.485
NOTCH3	Q9UM47-1.2	A1529C	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1529D	Neutral	0.048
NOTCH3	Q9UM47-1.2	A1529E	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1529F	Neutral	0.041
NOTCH3	Q9UM47-1.2	A1529G	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1529H	Neutral	0.043
NOTCH3	Q9UM47-1.2	A1529I	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1529K	Neutral	0.009
NOTCH3	Q9UM47-1.2	A1529L	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1529M	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1529N	Neutral	0.047
NOTCH3	Q9UM47-1.2	A1529P	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1529Q	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1529R	Neutral	0.009
NOTCH3	Q9UM47-1.2	A1529S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1529T	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1529V	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1529W	Neutral	0.15
NOTCH3	Q9UM47-1.2	A1529Y	Neutral	0.04
NOTCH3	Q9UM47-1.2	D1530A	Neutral	0.049
NOTCH3	Q9UM47-1.2	D1530C	Neutral	0.201
NOTCH3	Q9UM47-1.2	D1530E	Neutral	0.0
NOTCH3	Q9UM47-1.2	D1530F	Neutral	0.179
NOTCH3	Q9UM47-1.2	D1530G	Neutral	0.01
NOTCH3	Q9UM47-1.2	D1530H	Neutral	0.011
NOTCH3	Q9UM47-1.2	D1530I	Neutral	0.185
NOTCH3	Q9UM47-1.2	D1530K	Neutral	0.01
NOTCH3	Q9UM47-1.2	D1530L	Pathogenic	0.508
NOTCH3	Q9UM47-1.2	D1530M	Neutral	0.184
NOTCH3	Q9UM47-1.2	D1530N	Neutral	0.001
NOTCH3	Q9UM47-1.2	D1530P	Neutral	0.012
NOTCH3	Q9UM47-1.2	D1530Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	D1530R	Neutral	0.043
NOTCH3	Q9UM47-1.2	D1530S	Neutral	0.003
NOTCH3	Q9UM47-1.2	D1530T	Neutral	0.012
NOTCH3	Q9UM47-1.2	D1530V	Neutral	0.196
NOTCH3	Q9UM47-1.2	D1530W	Neutral	0.472
NOTCH3	Q9UM47-1.2	D1530Y	Neutral	0.174
NOTCH3	Q9UM47-1.2	F1531A	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	F1531C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	F1531D	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1531E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1531G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F1531H	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	F1531I	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	F1531K	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1531L	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	F1531M	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	F1531N	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1531P	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	F1531Q	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1531R	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1531S	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	F1531T	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	F1531V	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	F1531W	Neutral	0.447
NOTCH3	Q9UM47-1.2	F1531Y	Neutral	0.041
NOTCH3	Q9UM47-1.2	L1532A	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	L1532C	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	L1532D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1532E	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1532F	Neutral	0.367
NOTCH3	Q9UM47-1.2	L1532G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1532H	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1532I	Neutral	0.028
NOTCH3	Q9UM47-1.2	L1532K	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	L1532M	Neutral	0.028
NOTCH3	Q9UM47-1.2	L1532N	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L1532P	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L1532Q	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	L1532R	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	L1532S	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	L1532T	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	L1532V	Neutral	0.11
NOTCH3	Q9UM47-1.2	L1532W	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	L1532Y	Pathogenic	0.722
NOTCH3	Q9UM47-1.2	Q1533A	Neutral	0.156
NOTCH3	Q9UM47-1.2	Q1533C	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	Q1533D	Neutral	0.043
NOTCH3	Q9UM47-1.2	Q1533E	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q1533F	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	Q1533G	Neutral	0.439
NOTCH3	Q9UM47-1.2	Q1533H	Neutral	0.046
NOTCH3	Q9UM47-1.2	Q1533I	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	Q1533K	Neutral	0.01
NOTCH3	Q9UM47-1.2	Q1533L	Neutral	0.496
NOTCH3	Q9UM47-1.2	Q1533M	Neutral	0.045
NOTCH3	Q9UM47-1.2	Q1533N	Neutral	0.044
NOTCH3	Q9UM47-1.2	Q1533P	Neutral	0.169
NOTCH3	Q9UM47-1.2	Q1533R	Neutral	0.009
NOTCH3	Q9UM47-1.2	Q1533S	Neutral	0.04
NOTCH3	Q9UM47-1.2	Q1533T	Neutral	0.17
NOTCH3	Q9UM47-1.2	Q1533V	Neutral	0.496
NOTCH3	Q9UM47-1.2	Q1533W	Neutral	0.46
NOTCH3	Q9UM47-1.2	Q1533Y	Neutral	0.168
NOTCH3	Q9UM47-1.2	R1534A	Neutral	0.028
NOTCH3	Q9UM47-1.2	R1534C	Neutral	0.389
NOTCH3	Q9UM47-1.2	R1534D	Neutral	0.123
NOTCH3	Q9UM47-1.2	R1534E	Neutral	0.007
NOTCH3	Q9UM47-1.2	R1534F	Neutral	0.436
NOTCH3	Q9UM47-1.2	R1534G	Neutral	0.107
NOTCH3	Q9UM47-1.2	R1534H	Neutral	0.008
NOTCH3	Q9UM47-1.2	R1534I	Neutral	0.426
NOTCH3	Q9UM47-1.2	R1534K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R1534L	Neutral	0.14
NOTCH3	Q9UM47-1.2	R1534M	Neutral	0.034
NOTCH3	Q9UM47-1.2	R1534N	Neutral	0.007
NOTCH3	Q9UM47-1.2	R1534P	Neutral	0.124
NOTCH3	Q9UM47-1.2	R1534Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1534S	Neutral	0.028
NOTCH3	Q9UM47-1.2	R1534T	Neutral	0.03
NOTCH3	Q9UM47-1.2	R1534V	Neutral	0.407
NOTCH3	Q9UM47-1.2	R1534W	Neutral	0.435
NOTCH3	Q9UM47-1.2	R1534Y	Neutral	0.147
NOTCH3	Q9UM47-1.2	L1535A	Pathogenic	0.588
NOTCH3	Q9UM47-1.2	L1535C	Pathogenic	0.605
NOTCH3	Q9UM47-1.2	L1535D	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	L1535E	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	L1535F	Neutral	0.271
NOTCH3	Q9UM47-1.2	L1535G	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	L1535H	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	L1535I	Neutral	0.018
NOTCH3	Q9UM47-1.2	L1535K	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	L1535M	Neutral	0.018
NOTCH3	Q9UM47-1.2	L1535N	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	L1535P	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	L1535Q	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	L1535R	Pathogenic	0.882
NOTCH3	Q9UM47-1.2	L1535S	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	L1535T	Pathogenic	0.613
NOTCH3	Q9UM47-1.2	L1535V	Neutral	0.073
NOTCH3	Q9UM47-1.2	L1535W	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	L1535Y	Pathogenic	0.624
NOTCH3	Q9UM47-1.2	S1536A	Neutral	0.025
NOTCH3	Q9UM47-1.2	S1536C	Neutral	0.339
NOTCH3	Q9UM47-1.2	S1536D	Neutral	0.099
NOTCH3	Q9UM47-1.2	S1536E	Neutral	0.093
NOTCH3	Q9UM47-1.2	S1536F	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	S1536G	Neutral	0.096
NOTCH3	Q9UM47-1.2	S1536H	Neutral	0.31
NOTCH3	Q9UM47-1.2	S1536I	Pathogenic	0.67
NOTCH3	Q9UM47-1.2	S1536K	Neutral	0.085
NOTCH3	Q9UM47-1.2	S1536L	Pathogenic	0.67
NOTCH3	Q9UM47-1.2	S1536M	Neutral	0.307
NOTCH3	Q9UM47-1.2	S1536N	Neutral	0.023
NOTCH3	Q9UM47-1.2	S1536P	Neutral	0.335
NOTCH3	Q9UM47-1.2	S1536Q	Neutral	0.091
NOTCH3	Q9UM47-1.2	S1536R	Neutral	0.287
NOTCH3	Q9UM47-1.2	S1536T	Neutral	0.023
NOTCH3	Q9UM47-1.2	S1536V	Pathogenic	0.685
NOTCH3	Q9UM47-1.2	S1536W	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	S1536Y	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	A1537C	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1537D	Neutral	0.102
NOTCH3	Q9UM47-1.2	A1537E	Neutral	0.023
NOTCH3	Q9UM47-1.2	A1537F	Neutral	0.087
NOTCH3	Q9UM47-1.2	A1537G	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1537H	Neutral	0.092
NOTCH3	Q9UM47-1.2	A1537I	Neutral	0.021
NOTCH3	Q9UM47-1.2	A1537K	Neutral	0.021
NOTCH3	Q9UM47-1.2	A1537L	Neutral	0.021
NOTCH3	Q9UM47-1.2	A1537M	Neutral	0.021
NOTCH3	Q9UM47-1.2	A1537N	Neutral	0.1
NOTCH3	Q9UM47-1.2	A1537P	Neutral	0.024
NOTCH3	Q9UM47-1.2	A1537Q	Neutral	0.022
NOTCH3	Q9UM47-1.2	A1537R	Neutral	0.02
NOTCH3	Q9UM47-1.2	A1537S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1537T	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1537V	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1537W	Neutral	0.282
NOTCH3	Q9UM47-1.2	A1537Y	Neutral	0.085
NOTCH3	Q9UM47-1.2	I1538A	Neutral	0.158
NOTCH3	Q9UM47-1.2	I1538C	Neutral	0.167
NOTCH3	Q9UM47-1.2	I1538D	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	I1538E	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	I1538F	Neutral	0.046
NOTCH3	Q9UM47-1.2	I1538G	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	I1538H	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	I1538K	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	I1538L	Neutral	0.002
NOTCH3	Q9UM47-1.2	I1538M	Neutral	0.011
NOTCH3	Q9UM47-1.2	I1538N	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	I1538P	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	I1538Q	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	I1538R	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	I1538S	Neutral	0.466
NOTCH3	Q9UM47-1.2	I1538T	Neutral	0.171
NOTCH3	Q9UM47-1.2	I1538V	Neutral	0.0
NOTCH3	Q9UM47-1.2	I1538W	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	I1538Y	Neutral	0.178
NOTCH3	Q9UM47-1.2	L1539A	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	L1539C	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	L1539D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1539E	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	L1539F	Neutral	0.393
NOTCH3	Q9UM47-1.2	L1539G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1539H	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	L1539I	Neutral	0.032
NOTCH3	Q9UM47-1.2	L1539K	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	L1539M	Neutral	0.032
NOTCH3	Q9UM47-1.2	L1539N	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1539P	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1539Q	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	L1539R	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	L1539S	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	L1539T	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	L1539V	Neutral	0.122
NOTCH3	Q9UM47-1.2	L1539W	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	L1539Y	Pathogenic	0.744
NOTCH3	Q9UM47-1.2	R1540A	Neutral	0.247
NOTCH3	Q9UM47-1.2	R1540C	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	R1540D	Pathogenic	0.619
NOTCH3	Q9UM47-1.2	R1540E	Neutral	0.077
NOTCH3	Q9UM47-1.2	R1540F	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	R1540G	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	R1540H	Neutral	0.08
NOTCH3	Q9UM47-1.2	R1540I	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	R1540K	Neutral	0.004
NOTCH3	Q9UM47-1.2	R1540L	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	R1540M	Neutral	0.292
NOTCH3	Q9UM47-1.2	R1540N	Neutral	0.074
NOTCH3	Q9UM47-1.2	R1540P	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	R1540Q	Neutral	0.019
NOTCH3	Q9UM47-1.2	R1540S	Neutral	0.251
NOTCH3	Q9UM47-1.2	R1540T	Neutral	0.266
NOTCH3	Q9UM47-1.2	R1540V	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	R1540W	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	R1540Y	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	T1541A	Neutral	0.45
NOTCH3	Q9UM47-1.2	T1541C	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	T1541D	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	T1541E	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	T1541F	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	T1541G	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	T1541H	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	T1541I	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	T1541K	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	T1541L	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	T1541M	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	T1541N	Neutral	0.473
NOTCH3	Q9UM47-1.2	T1541P	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	T1541Q	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	T1541R	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	T1541S	Neutral	0.155
NOTCH3	Q9UM47-1.2	T1541V	Neutral	0.465
NOTCH3	Q9UM47-1.2	T1541W	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	T1541Y	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	S1542A	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1542C	Neutral	0.057
NOTCH3	Q9UM47-1.2	S1542D	Neutral	0.013
NOTCH3	Q9UM47-1.2	S1542E	Neutral	0.012
NOTCH3	Q9UM47-1.2	S1542F	Neutral	0.186
NOTCH3	Q9UM47-1.2	S1542G	Neutral	0.012
NOTCH3	Q9UM47-1.2	S1542H	Neutral	0.05
NOTCH3	Q9UM47-1.2	S1542I	Neutral	0.193
NOTCH3	Q9UM47-1.2	S1542K	Neutral	0.011
NOTCH3	Q9UM47-1.2	S1542L	Neutral	0.192
NOTCH3	Q9UM47-1.2	S1542M	Neutral	0.05
NOTCH3	Q9UM47-1.2	S1542N	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1542P	Neutral	0.056
NOTCH3	Q9UM47-1.2	S1542Q	Neutral	0.012
NOTCH3	Q9UM47-1.2	S1542R	Neutral	0.045
NOTCH3	Q9UM47-1.2	S1542T	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1542V	Neutral	0.203
NOTCH3	Q9UM47-1.2	S1542W	Neutral	0.484
NOTCH3	Q9UM47-1.2	S1542Y	Neutral	0.182
NOTCH3	Q9UM47-1.2	L1543A	Neutral	0.261
NOTCH3	Q9UM47-1.2	L1543C	Neutral	0.274
NOTCH3	Q9UM47-1.2	L1543D	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	L1543E	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	L1543F	Neutral	0.084
NOTCH3	Q9UM47-1.2	L1543G	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	L1543H	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	L1543I	Neutral	0.005
NOTCH3	Q9UM47-1.2	L1543K	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	L1543M	Neutral	0.005
NOTCH3	Q9UM47-1.2	L1543N	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	L1543P	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	L1543Q	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	L1543R	Pathogenic	0.649
NOTCH3	Q9UM47-1.2	L1543S	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	L1543T	Neutral	0.281
NOTCH3	Q9UM47-1.2	L1543V	Neutral	0.019
NOTCH3	Q9UM47-1.2	L1543W	Pathogenic	0.631
NOTCH3	Q9UM47-1.2	L1543Y	Neutral	0.291
NOTCH3	Q9UM47-1.2	R1544A	Neutral	0.353
NOTCH3	Q9UM47-1.2	R1544C	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	R1544D	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	R1544E	Neutral	0.123
NOTCH3	Q9UM47-1.2	R1544F	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	R1544G	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	R1544H	Neutral	0.127
NOTCH3	Q9UM47-1.2	R1544I	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	R1544K	Neutral	0.007
NOTCH3	Q9UM47-1.2	R1544L	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	R1544M	Neutral	0.406
NOTCH3	Q9UM47-1.2	R1544N	Neutral	0.117
NOTCH3	Q9UM47-1.2	R1544P	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	R1544Q	Neutral	0.03
NOTCH3	Q9UM47-1.2	R1544S	Neutral	0.357
NOTCH3	Q9UM47-1.2	R1544T	Neutral	0.376
NOTCH3	Q9UM47-1.2	R1544V	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	R1544W	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	R1544Y	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	F1545A	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	F1545C	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	F1545D	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	F1545E	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	F1545G	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	F1545H	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	F1545I	Neutral	0.334
NOTCH3	Q9UM47-1.2	F1545K	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	F1545L	Neutral	0.334
NOTCH3	Q9UM47-1.2	F1545M	Neutral	0.335
NOTCH3	Q9UM47-1.2	F1545N	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	F1545P	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	F1545Q	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	F1545R	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	F1545S	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	F1545T	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	F1545V	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	F1545W	Neutral	0.094
NOTCH3	Q9UM47-1.2	F1545Y	Neutral	0.005
NOTCH3	Q9UM47-1.2	R1546A	Neutral	0.284
NOTCH3	Q9UM47-1.2	R1546C	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	R1546D	Pathogenic	0.663
NOTCH3	Q9UM47-1.2	R1546E	Neutral	0.092
NOTCH3	Q9UM47-1.2	R1546F	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	R1546G	Pathogenic	0.626
NOTCH3	Q9UM47-1.2	R1546H	Neutral	0.096
NOTCH3	Q9UM47-1.2	R1546I	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	R1546K	Neutral	0.005
NOTCH3	Q9UM47-1.2	R1546L	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	R1546M	Neutral	0.333
NOTCH3	Q9UM47-1.2	R1546N	Neutral	0.088
NOTCH3	Q9UM47-1.2	R1546P	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	R1546Q	Neutral	0.022
NOTCH3	Q9UM47-1.2	R1546S	Neutral	0.288
NOTCH3	Q9UM47-1.2	R1546T	Neutral	0.305
NOTCH3	Q9UM47-1.2	R1546V	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	R1546W	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	R1546Y	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	L1547A	Neutral	0.069
NOTCH3	Q9UM47-1.2	L1547C	Neutral	0.074
NOTCH3	Q9UM47-1.2	L1547D	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	L1547E	Pathogenic	0.647
NOTCH3	Q9UM47-1.2	L1547F	Neutral	0.019
NOTCH3	Q9UM47-1.2	L1547G	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	L1547H	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	L1547I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1547K	Neutral	0.291
NOTCH3	Q9UM47-1.2	L1547M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1547N	Pathogenic	0.635
NOTCH3	Q9UM47-1.2	L1547P	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	L1547Q	Neutral	0.29
NOTCH3	Q9UM47-1.2	L1547R	Neutral	0.28
NOTCH3	Q9UM47-1.2	L1547S	Neutral	0.258
NOTCH3	Q9UM47-1.2	L1547T	Neutral	0.076
NOTCH3	Q9UM47-1.2	L1547V	Neutral	0.004
NOTCH3	Q9UM47-1.2	L1547W	Neutral	0.265
NOTCH3	Q9UM47-1.2	L1547Y	Neutral	0.08
NOTCH3	Q9UM47-1.2	D1548A	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	D1548C	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	D1548E	Neutral	0.02
NOTCH3	Q9UM47-1.2	D1548F	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	D1548G	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	D1548H	Pathogenic	0.656
NOTCH3	Q9UM47-1.2	D1548I	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	D1548K	Pathogenic	0.64
NOTCH3	Q9UM47-1.2	D1548L	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	D1548M	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	D1548N	Neutral	0.091
NOTCH3	Q9UM47-1.2	D1548P	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	D1548Q	Neutral	0.298
NOTCH3	Q9UM47-1.2	D1548R	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	D1548S	Neutral	0.303
NOTCH3	Q9UM47-1.2	D1548T	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	D1548V	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	D1548W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	D1548Y	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	A1549C	Neutral	0.017
NOTCH3	Q9UM47-1.2	A1549D	Neutral	0.256
NOTCH3	Q9UM47-1.2	A1549E	Neutral	0.066
NOTCH3	Q9UM47-1.2	A1549F	Neutral	0.226
NOTCH3	Q9UM47-1.2	A1549G	Neutral	0.017
NOTCH3	Q9UM47-1.2	A1549H	Neutral	0.235
NOTCH3	Q9UM47-1.2	A1549I	Neutral	0.063
NOTCH3	Q9UM47-1.2	A1549K	Neutral	0.06
NOTCH3	Q9UM47-1.2	A1549L	Neutral	0.063
NOTCH3	Q9UM47-1.2	A1549M	Neutral	0.062
NOTCH3	Q9UM47-1.2	A1549N	Neutral	0.252
NOTCH3	Q9UM47-1.2	A1549P	Neutral	0.07
NOTCH3	Q9UM47-1.2	A1549Q	Neutral	0.064
NOTCH3	Q9UM47-1.2	A1549R	Neutral	0.057
NOTCH3	Q9UM47-1.2	A1549S	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1549T	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1549V	Neutral	0.015
NOTCH3	Q9UM47-1.2	A1549W	Pathogenic	0.544
NOTCH3	Q9UM47-1.2	A1549Y	Neutral	0.22
NOTCH3	Q9UM47-1.2	H1550A	Neutral	0.135
NOTCH3	Q9UM47-1.2	H1550C	Neutral	0.434
NOTCH3	Q9UM47-1.2	H1550D	Neutral	0.036
NOTCH3	Q9UM47-1.2	H1550E	Neutral	0.009
NOTCH3	Q9UM47-1.2	H1550F	Neutral	0.038
NOTCH3	Q9UM47-1.2	H1550G	Neutral	0.127
NOTCH3	Q9UM47-1.2	H1550I	Neutral	0.461
NOTCH3	Q9UM47-1.2	H1550K	Neutral	0.038
NOTCH3	Q9UM47-1.2	H1550L	Neutral	0.461
NOTCH3	Q9UM47-1.2	H1550M	Neutral	0.157
NOTCH3	Q9UM47-1.2	H1550N	Neutral	0.002
NOTCH3	Q9UM47-1.2	H1550P	Neutral	0.146
NOTCH3	Q9UM47-1.2	H1550Q	Neutral	0.009
NOTCH3	Q9UM47-1.2	H1550R	Neutral	0.008
NOTCH3	Q9UM47-1.2	H1550S	Neutral	0.034
NOTCH3	Q9UM47-1.2	H1550T	Neutral	0.147
NOTCH3	Q9UM47-1.2	H1550V	Neutral	0.453
NOTCH3	Q9UM47-1.2	H1550W	Neutral	0.14
NOTCH3	Q9UM47-1.2	H1550Y	Neutral	0.0
NOTCH3	Q9UM47-1.2	G1551A	Neutral	0.161
NOTCH3	Q9UM47-1.2	G1551C	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	G1551D	Neutral	0.445
NOTCH3	Q9UM47-1.2	G1551E	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	G1551F	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	G1551H	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	G1551I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	G1551K	Pathogenic	0.755
NOTCH3	Q9UM47-1.2	G1551L	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	G1551M	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	G1551N	Neutral	0.147
NOTCH3	Q9UM47-1.2	G1551P	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	G1551Q	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	G1551R	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	G1551S	Neutral	0.158
NOTCH3	Q9UM47-1.2	G1551T	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	G1551V	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	G1551W	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	G1551Y	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	Q1552A	Neutral	0.076
NOTCH3	Q9UM47-1.2	Q1552C	Pathogenic	0.648
NOTCH3	Q9UM47-1.2	Q1552D	Neutral	0.019
NOTCH3	Q9UM47-1.2	Q1552E	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1552F	Pathogenic	0.656
NOTCH3	Q9UM47-1.2	Q1552G	Neutral	0.258
NOTCH3	Q9UM47-1.2	Q1552H	Neutral	0.021
NOTCH3	Q9UM47-1.2	Q1552I	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	Q1552K	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q1552L	Neutral	0.304
NOTCH3	Q9UM47-1.2	Q1552M	Neutral	0.021
NOTCH3	Q9UM47-1.2	Q1552N	Neutral	0.02
NOTCH3	Q9UM47-1.2	Q1552P	Neutral	0.083
NOTCH3	Q9UM47-1.2	Q1552R	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q1552S	Neutral	0.018
NOTCH3	Q9UM47-1.2	Q1552T	Neutral	0.083
NOTCH3	Q9UM47-1.2	Q1552V	Neutral	0.304
NOTCH3	Q9UM47-1.2	Q1552W	Neutral	0.274
NOTCH3	Q9UM47-1.2	Q1552Y	Neutral	0.082
NOTCH3	Q9UM47-1.2	A1553C	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1553D	Neutral	0.079
NOTCH3	Q9UM47-1.2	A1553E	Neutral	0.017
NOTCH3	Q9UM47-1.2	A1553F	Neutral	0.068
NOTCH3	Q9UM47-1.2	A1553G	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1553H	Neutral	0.071
NOTCH3	Q9UM47-1.2	A1553I	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1553K	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1553L	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1553M	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1553N	Neutral	0.078
NOTCH3	Q9UM47-1.2	A1553P	Neutral	0.018
NOTCH3	Q9UM47-1.2	A1553Q	Neutral	0.017
NOTCH3	Q9UM47-1.2	A1553R	Neutral	0.015
NOTCH3	Q9UM47-1.2	A1553S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1553T	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1553V	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1553W	Neutral	0.23
NOTCH3	Q9UM47-1.2	A1553Y	Neutral	0.066
NOTCH3	Q9UM47-1.2	M1554A	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	M1554C	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	M1554D	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	M1554E	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	M1554F	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	M1554G	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	M1554H	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	M1554I	Pathogenic	0.606
NOTCH3	Q9UM47-1.2	M1554K	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	M1554L	Neutral	0.252
NOTCH3	Q9UM47-1.2	M1554N	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	M1554P	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	M1554Q	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	M1554R	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	M1554S	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	M1554T	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	M1554V	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	M1554W	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	M1554Y	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	V1555A	Neutral	0.155
NOTCH3	Q9UM47-1.2	V1555C	Neutral	0.473
NOTCH3	Q9UM47-1.2	V1555D	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	V1555E	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	V1555F	Neutral	0.463
NOTCH3	Q9UM47-1.2	V1555G	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	V1555H	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	V1555I	Neutral	0.002
NOTCH3	Q9UM47-1.2	V1555K	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	V1555L	Neutral	0.042
NOTCH3	Q9UM47-1.2	V1555M	Neutral	0.041
NOTCH3	Q9UM47-1.2	V1555N	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	V1555P	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	V1555Q	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	V1555R	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	V1555S	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	V1555T	Neutral	0.169
NOTCH3	Q9UM47-1.2	V1555W	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	V1555Y	Neutral	0.456
NOTCH3	Q9UM47-1.2	F1556A	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	F1556C	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	F1556D	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	F1556E	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	F1556G	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	F1556H	Pathogenic	0.646
NOTCH3	Q9UM47-1.2	F1556I	Neutral	0.289
NOTCH3	Q9UM47-1.2	F1556K	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	F1556L	Neutral	0.289
NOTCH3	Q9UM47-1.2	F1556M	Neutral	0.289
NOTCH3	Q9UM47-1.2	F1556N	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	F1556P	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	F1556Q	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	F1556R	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	F1556S	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	F1556T	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	F1556V	Pathogenic	0.633
NOTCH3	Q9UM47-1.2	F1556W	Neutral	0.077
NOTCH3	Q9UM47-1.2	F1556Y	Neutral	0.004
NOTCH3	Q9UM47-1.2	P1557A	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	P1557C	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	P1557D	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	P1557E	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	P1557F	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P1557G	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	P1557H	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	P1557I	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	P1557K	Pathogenic	0.644
NOTCH3	Q9UM47-1.2	P1557L	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	P1557M	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	P1557N	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	P1557Q	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	P1557R	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	P1557S	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	P1557T	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	P1557V	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	P1557W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	P1557Y	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	Y1558A	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	Y1558C	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	Y1558D	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	Y1558E	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	Y1558F	Neutral	0.021
NOTCH3	Q9UM47-1.2	Y1558G	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	Y1558H	Neutral	0.085
NOTCH3	Q9UM47-1.2	Y1558I	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	Y1558K	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	Y1558L	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	Y1558M	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	Y1558N	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	Y1558P	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	Y1558Q	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	Y1558R	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	Y1558S	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	Y1558T	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	Y1558V	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	Y1558W	Neutral	0.085
NOTCH3	Q9UM47-1.2	H1559A	Neutral	0.268
NOTCH3	Q9UM47-1.2	H1559C	Pathogenic	0.643
NOTCH3	Q9UM47-1.2	H1559D	Neutral	0.081
NOTCH3	Q9UM47-1.2	H1559E	Neutral	0.02
NOTCH3	Q9UM47-1.2	H1559F	Neutral	0.085
NOTCH3	Q9UM47-1.2	H1559G	Neutral	0.254
NOTCH3	Q9UM47-1.2	H1559I	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	H1559K	Neutral	0.084
NOTCH3	Q9UM47-1.2	H1559L	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	H1559M	Neutral	0.305
NOTCH3	Q9UM47-1.2	H1559N	Neutral	0.004
NOTCH3	Q9UM47-1.2	H1559P	Neutral	0.286
NOTCH3	Q9UM47-1.2	H1559Q	Neutral	0.021
NOTCH3	Q9UM47-1.2	H1559R	Neutral	0.019
NOTCH3	Q9UM47-1.2	H1559S	Neutral	0.076
NOTCH3	Q9UM47-1.2	H1559T	Neutral	0.288
NOTCH3	Q9UM47-1.2	H1559V	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	H1559W	Neutral	0.275
NOTCH3	Q9UM47-1.2	H1559Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1560A	Neutral	0.136
NOTCH3	Q9UM47-1.2	R1560C	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	R1560D	Neutral	0.438
NOTCH3	Q9UM47-1.2	R1560E	Neutral	0.039
NOTCH3	Q9UM47-1.2	R1560F	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	R1560G	Neutral	0.4
NOTCH3	Q9UM47-1.2	R1560H	Neutral	0.04
NOTCH3	Q9UM47-1.2	R1560I	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	R1560K	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1560L	Neutral	0.475
NOTCH3	Q9UM47-1.2	R1560M	Neutral	0.165
NOTCH3	Q9UM47-1.2	R1560N	Neutral	0.037
NOTCH3	Q9UM47-1.2	R1560P	Neutral	0.44
NOTCH3	Q9UM47-1.2	R1560Q	Neutral	0.009
NOTCH3	Q9UM47-1.2	R1560S	Neutral	0.139
NOTCH3	Q9UM47-1.2	R1560T	Neutral	0.148
NOTCH3	Q9UM47-1.2	R1560V	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	R1560W	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	R1560Y	Neutral	0.49
NOTCH3	Q9UM47-1.2	P1561A	Neutral	0.028
NOTCH3	Q9UM47-1.2	P1561C	Neutral	0.389
NOTCH3	Q9UM47-1.2	P1561D	Neutral	0.03
NOTCH3	Q9UM47-1.2	P1561E	Neutral	0.028
NOTCH3	Q9UM47-1.2	P1561F	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	P1561G	Neutral	0.108
NOTCH3	Q9UM47-1.2	P1561H	Neutral	0.113
NOTCH3	Q9UM47-1.2	P1561I	Neutral	0.364
NOTCH3	Q9UM47-1.2	P1561K	Neutral	0.026
NOTCH3	Q9UM47-1.2	P1561L	Neutral	0.363
NOTCH3	Q9UM47-1.2	P1561M	Neutral	0.111
NOTCH3	Q9UM47-1.2	P1561N	Neutral	0.123
NOTCH3	Q9UM47-1.2	P1561Q	Neutral	0.028
NOTCH3	Q9UM47-1.2	P1561R	Neutral	0.103
NOTCH3	Q9UM47-1.2	P1561S	Neutral	0.029
NOTCH3	Q9UM47-1.2	P1561T	Neutral	0.03
NOTCH3	Q9UM47-1.2	P1561V	Neutral	0.118
NOTCH3	Q9UM47-1.2	P1561W	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	P1561Y	Neutral	0.347
NOTCH3	Q9UM47-1.2	S1562A	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1562C	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1562D	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1562E	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1562F	Neutral	0.019
NOTCH3	Q9UM47-1.2	S1562G	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1562H	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1562I	Neutral	0.02
NOTCH3	Q9UM47-1.2	S1562K	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1562L	Neutral	0.02
NOTCH3	Q9UM47-1.2	S1562M	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1562N	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1562P	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1562Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1562R	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1562T	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1562V	Neutral	0.022
NOTCH3	Q9UM47-1.2	S1562W	Neutral	0.075
NOTCH3	Q9UM47-1.2	S1562Y	Neutral	0.019
NOTCH3	Q9UM47-1.2	P1563A	Neutral	0.004
NOTCH3	Q9UM47-1.2	P1563C	Neutral	0.083
NOTCH3	Q9UM47-1.2	P1563D	Neutral	0.004
NOTCH3	Q9UM47-1.2	P1563E	Neutral	0.004
NOTCH3	Q9UM47-1.2	P1563F	Neutral	0.261
NOTCH3	Q9UM47-1.2	P1563G	Neutral	0.017
NOTCH3	Q9UM47-1.2	P1563H	Neutral	0.018
NOTCH3	Q9UM47-1.2	P1563I	Neutral	0.075
NOTCH3	Q9UM47-1.2	P1563K	Neutral	0.004
NOTCH3	Q9UM47-1.2	P1563L	Neutral	0.075
NOTCH3	Q9UM47-1.2	P1563M	Neutral	0.017
NOTCH3	Q9UM47-1.2	P1563N	Neutral	0.019
NOTCH3	Q9UM47-1.2	P1563Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	P1563R	Neutral	0.016
NOTCH3	Q9UM47-1.2	P1563S	Neutral	0.004
NOTCH3	Q9UM47-1.2	P1563T	Neutral	0.004
NOTCH3	Q9UM47-1.2	P1563V	Neutral	0.019
NOTCH3	Q9UM47-1.2	P1563W	Neutral	0.241
NOTCH3	Q9UM47-1.2	P1563Y	Neutral	0.07
NOTCH3	Q9UM47-1.2	G1564A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1564C	Neutral	0.181
NOTCH3	Q9UM47-1.2	G1564D	Neutral	0.01
NOTCH3	Q9UM47-1.2	G1564E	Neutral	0.042
NOTCH3	Q9UM47-1.2	G1564F	Neutral	0.155
NOTCH3	Q9UM47-1.2	G1564H	Neutral	0.041
NOTCH3	Q9UM47-1.2	G1564I	Neutral	0.466
NOTCH3	Q9UM47-1.2	G1564K	Neutral	0.039
NOTCH3	Q9UM47-1.2	G1564L	Neutral	0.466
NOTCH3	Q9UM47-1.2	G1564M	Neutral	0.16
NOTCH3	Q9UM47-1.2	G1564N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1564P	Neutral	0.045
NOTCH3	Q9UM47-1.2	G1564Q	Neutral	0.041
NOTCH3	Q9UM47-1.2	G1564R	Neutral	0.037
NOTCH3	Q9UM47-1.2	G1564S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1564T	Neutral	0.045
NOTCH3	Q9UM47-1.2	G1564V	Neutral	0.171
NOTCH3	Q9UM47-1.2	G1564W	Neutral	0.035
NOTCH3	Q9UM47-1.2	G1564Y	Neutral	0.152
NOTCH3	Q9UM47-1.2	S1565A	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1565C	Neutral	0.007
NOTCH3	Q9UM47-1.2	S1565D	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1565E	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1565F	Neutral	0.026
NOTCH3	Q9UM47-1.2	S1565G	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1565H	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1565I	Neutral	0.028
NOTCH3	Q9UM47-1.2	S1565K	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1565L	Neutral	0.028
NOTCH3	Q9UM47-1.2	S1565M	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1565N	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1565P	Neutral	0.007
NOTCH3	Q9UM47-1.2	S1565Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1565R	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1565T	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1565V	Neutral	0.029
NOTCH3	Q9UM47-1.2	S1565W	Neutral	0.1
NOTCH3	Q9UM47-1.2	S1565Y	Neutral	0.026
NOTCH3	Q9UM47-1.2	E1566A	Neutral	0.016
NOTCH3	Q9UM47-1.2	E1566C	Pathogenic	0.617
NOTCH3	Q9UM47-1.2	E1566D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1566F	Neutral	0.26
NOTCH3	Q9UM47-1.2	E1566G	Neutral	0.062
NOTCH3	Q9UM47-1.2	E1566H	Neutral	0.004
NOTCH3	Q9UM47-1.2	E1566I	Neutral	0.269
NOTCH3	Q9UM47-1.2	E1566K	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1566L	Neutral	0.268
NOTCH3	Q9UM47-1.2	E1566M	Neutral	0.074
NOTCH3	Q9UM47-1.2	E1566N	Neutral	0.004
NOTCH3	Q9UM47-1.2	E1566P	Neutral	0.017
NOTCH3	Q9UM47-1.2	E1566Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1566R	Neutral	0.003
NOTCH3	Q9UM47-1.2	E1566S	Neutral	0.004
NOTCH3	Q9UM47-1.2	E1566T	Neutral	0.017
NOTCH3	Q9UM47-1.2	E1566V	Neutral	0.077
NOTCH3	Q9UM47-1.2	E1566W	Neutral	0.241
NOTCH3	Q9UM47-1.2	E1566Y	Neutral	0.07
NOTCH3	Q9UM47-1.2	P1567A	Neutral	0.003
NOTCH3	Q9UM47-1.2	P1567C	Neutral	0.058
NOTCH3	Q9UM47-1.2	P1567D	Neutral	0.003
NOTCH3	Q9UM47-1.2	P1567E	Neutral	0.003
NOTCH3	Q9UM47-1.2	P1567F	Neutral	0.195
NOTCH3	Q9UM47-1.2	P1567G	Neutral	0.012
NOTCH3	Q9UM47-1.2	P1567H	Neutral	0.012
NOTCH3	Q9UM47-1.2	P1567I	Neutral	0.053
NOTCH3	Q9UM47-1.2	P1567K	Neutral	0.003
NOTCH3	Q9UM47-1.2	P1567L	Neutral	0.053
NOTCH3	Q9UM47-1.2	P1567M	Neutral	0.012
NOTCH3	Q9UM47-1.2	P1567N	Neutral	0.013
NOTCH3	Q9UM47-1.2	P1567Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	P1567R	Neutral	0.011
NOTCH3	Q9UM47-1.2	P1567S	Neutral	0.003
NOTCH3	Q9UM47-1.2	P1567T	Neutral	0.003
NOTCH3	Q9UM47-1.2	P1567V	Neutral	0.013
NOTCH3	Q9UM47-1.2	P1567W	Neutral	0.179
NOTCH3	Q9UM47-1.2	P1567Y	Neutral	0.049
NOTCH3	Q9UM47-1.2	R1568A	Neutral	0.465
NOTCH3	Q9UM47-1.2	R1568C	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	R1568D	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	R1568E	Neutral	0.182
NOTCH3	Q9UM47-1.2	R1568F	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	R1568G	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	R1568H	Neutral	0.188
NOTCH3	Q9UM47-1.2	R1568I	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	R1568K	Neutral	0.012
NOTCH3	Q9UM47-1.2	R1568L	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	R1568M	Pathogenic	0.522
NOTCH3	Q9UM47-1.2	R1568N	Neutral	0.175
NOTCH3	Q9UM47-1.2	R1568P	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	R1568Q	Neutral	0.048
NOTCH3	Q9UM47-1.2	R1568S	Neutral	0.47
NOTCH3	Q9UM47-1.2	R1568T	Neutral	0.49
NOTCH3	Q9UM47-1.2	R1568V	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	R1568W	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	R1568Y	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	A1569C	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1569D	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1569E	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1569F	Neutral	0.014
NOTCH3	Q9UM47-1.2	A1569G	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1569H	Neutral	0.014
NOTCH3	Q9UM47-1.2	A1569I	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1569K	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1569L	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1569M	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1569N	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1569P	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1569Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1569R	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1569S	Neutral	0.0
NOTCH3	Q9UM47-1.2	A1569T	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1569V	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1569W	Neutral	0.053
NOTCH3	Q9UM47-1.2	A1569Y	Neutral	0.013
NOTCH3	Q9UM47-1.2	R1570A	Neutral	0.491
NOTCH3	Q9UM47-1.2	R1570C	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	R1570D	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	R1570E	Neutral	0.198
NOTCH3	Q9UM47-1.2	R1570F	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	R1570G	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	R1570H	Neutral	0.205
NOTCH3	Q9UM47-1.2	R1570I	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	R1570K	Neutral	0.013
NOTCH3	Q9UM47-1.2	R1570L	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	R1570M	Pathogenic	0.547
NOTCH3	Q9UM47-1.2	R1570N	Neutral	0.19
NOTCH3	Q9UM47-1.2	R1570P	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	R1570Q	Neutral	0.053
NOTCH3	Q9UM47-1.2	R1570S	Neutral	0.496
NOTCH3	Q9UM47-1.2	R1570T	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	R1570V	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	R1570W	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	R1570Y	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	R1571A	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	R1571C	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	R1571D	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	R1571E	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	R1571F	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	R1571G	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	R1571H	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	R1571I	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	R1571K	Neutral	0.106
NOTCH3	Q9UM47-1.2	R1571L	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	R1571M	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	R1571N	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	R1571P	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	R1571Q	Neutral	0.334
NOTCH3	Q9UM47-1.2	R1571S	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	R1571T	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	R1571V	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	R1571W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	R1571Y	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	E1572A	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	E1572C	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	E1572D	Neutral	0.029
NOTCH3	Q9UM47-1.2	E1572F	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	E1572G	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	E1572H	Neutral	0.396
NOTCH3	Q9UM47-1.2	E1572I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	E1572K	Neutral	0.118
NOTCH3	Q9UM47-1.2	E1572L	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	E1572M	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	E1572N	Neutral	0.391
NOTCH3	Q9UM47-1.2	E1572P	Pathogenic	0.742
NOTCH3	Q9UM47-1.2	E1572Q	Neutral	0.031
NOTCH3	Q9UM47-1.2	E1572R	Neutral	0.368
NOTCH3	Q9UM47-1.2	E1572S	Neutral	0.371
NOTCH3	Q9UM47-1.2	E1572T	Pathogenic	0.744
NOTCH3	Q9UM47-1.2	E1572V	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	E1572W	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	E1572Y	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	L1573A	Neutral	0.459
NOTCH3	Q9UM47-1.2	L1573C	Neutral	0.475
NOTCH3	Q9UM47-1.2	L1573D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	L1573E	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	L1573F	Neutral	0.18
NOTCH3	Q9UM47-1.2	L1573G	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	L1573H	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	L1573I	Neutral	0.011
NOTCH3	Q9UM47-1.2	L1573K	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	L1573M	Neutral	0.011
NOTCH3	Q9UM47-1.2	L1573N	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	L1573P	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	L1573Q	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	L1573R	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	L1573S	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	L1573T	Neutral	0.484
NOTCH3	Q9UM47-1.2	L1573V	Neutral	0.045
NOTCH3	Q9UM47-1.2	L1573W	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	L1573Y	Neutral	0.496
NOTCH3	Q9UM47-1.2	A1574C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1574D	Neutral	0.053
NOTCH3	Q9UM47-1.2	A1574E	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1574F	Neutral	0.046
NOTCH3	Q9UM47-1.2	A1574G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1574H	Neutral	0.048
NOTCH3	Q9UM47-1.2	A1574I	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1574K	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1574L	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1574M	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1574N	Neutral	0.052
NOTCH3	Q9UM47-1.2	A1574P	Neutral	0.012
NOTCH3	Q9UM47-1.2	A1574Q	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1574R	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1574S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1574T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1574V	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1574W	Neutral	0.164
NOTCH3	Q9UM47-1.2	A1574Y	Neutral	0.044
NOTCH3	Q9UM47-1.2	P1575A	Neutral	0.072
NOTCH3	Q9UM47-1.2	P1575C	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	P1575D	Neutral	0.078
NOTCH3	Q9UM47-1.2	P1575E	Neutral	0.073
NOTCH3	Q9UM47-1.2	P1575F	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	P1575G	Neutral	0.247
NOTCH3	Q9UM47-1.2	P1575H	Neutral	0.257
NOTCH3	Q9UM47-1.2	P1575I	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	P1575K	Neutral	0.067
NOTCH3	Q9UM47-1.2	P1575L	Pathogenic	0.606
NOTCH3	Q9UM47-1.2	P1575M	Neutral	0.252
NOTCH3	Q9UM47-1.2	P1575N	Neutral	0.274
NOTCH3	Q9UM47-1.2	P1575Q	Neutral	0.072
NOTCH3	Q9UM47-1.2	P1575R	Neutral	0.237
NOTCH3	Q9UM47-1.2	P1575S	Neutral	0.073
NOTCH3	Q9UM47-1.2	P1575T	Neutral	0.077
NOTCH3	Q9UM47-1.2	P1575V	Neutral	0.266
NOTCH3	Q9UM47-1.2	P1575W	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	P1575Y	Pathogenic	0.589
NOTCH3	Q9UM47-1.2	E1576A	Neutral	0.264
NOTCH3	Q9UM47-1.2	E1576C	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	E1576D	Neutral	0.004
NOTCH3	Q9UM47-1.2	E1576F	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	E1576G	Pathogenic	0.602
NOTCH3	Q9UM47-1.2	E1576H	Neutral	0.082
NOTCH3	Q9UM47-1.2	E1576I	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	E1576K	Neutral	0.018
NOTCH3	Q9UM47-1.2	E1576L	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	E1576M	Pathogenic	0.646
NOTCH3	Q9UM47-1.2	E1576N	Neutral	0.081
NOTCH3	Q9UM47-1.2	E1576P	Neutral	0.282
NOTCH3	Q9UM47-1.2	E1576Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	E1576R	Neutral	0.074
NOTCH3	Q9UM47-1.2	E1576S	Neutral	0.074
NOTCH3	Q9UM47-1.2	E1576T	Neutral	0.284
NOTCH3	Q9UM47-1.2	E1576V	Pathogenic	0.656
NOTCH3	Q9UM47-1.2	E1576W	Pathogenic	0.878
NOTCH3	Q9UM47-1.2	E1576Y	Pathogenic	0.631
NOTCH3	Q9UM47-1.2	V1577A	Neutral	0.121
NOTCH3	Q9UM47-1.2	V1577C	Neutral	0.402
NOTCH3	Q9UM47-1.2	V1577D	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	V1577E	Pathogenic	0.767
NOTCH3	Q9UM47-1.2	V1577F	Neutral	0.393
NOTCH3	Q9UM47-1.2	V1577G	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	V1577H	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	V1577I	Neutral	0.002
NOTCH3	Q9UM47-1.2	V1577K	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	V1577L	Neutral	0.032
NOTCH3	Q9UM47-1.2	V1577M	Neutral	0.031
NOTCH3	Q9UM47-1.2	V1577N	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	V1577P	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	V1577Q	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	V1577R	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	V1577S	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	V1577T	Neutral	0.133
NOTCH3	Q9UM47-1.2	V1577W	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	V1577Y	Neutral	0.387
NOTCH3	Q9UM47-1.2	I1578A	Neutral	0.223
NOTCH3	Q9UM47-1.2	I1578C	Neutral	0.235
NOTCH3	Q9UM47-1.2	I1578D	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	I1578E	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	I1578F	Neutral	0.069
NOTCH3	Q9UM47-1.2	I1578G	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	I1578H	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	I1578K	Pathogenic	0.878
NOTCH3	Q9UM47-1.2	I1578L	Neutral	0.004
NOTCH3	Q9UM47-1.2	I1578M	Neutral	0.017
NOTCH3	Q9UM47-1.2	I1578N	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	I1578P	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	I1578Q	Pathogenic	0.878
NOTCH3	Q9UM47-1.2	I1578R	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	I1578S	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	I1578T	Neutral	0.241
NOTCH3	Q9UM47-1.2	I1578V	Neutral	0.001
NOTCH3	Q9UM47-1.2	I1578W	Pathogenic	0.864
NOTCH3	Q9UM47-1.2	I1578Y	Neutral	0.25
NOTCH3	Q9UM47-1.2	G1579A	Neutral	0.226
NOTCH3	Q9UM47-1.2	G1579C	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G1579D	Pathogenic	0.549
NOTCH3	Q9UM47-1.2	G1579E	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	G1579F	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G1579H	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	G1579I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1579K	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G1579L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1579M	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G1579N	Neutral	0.208
NOTCH3	Q9UM47-1.2	G1579P	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G1579Q	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G1579R	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	G1579S	Neutral	0.222
NOTCH3	Q9UM47-1.2	G1579T	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G1579V	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G1579W	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	G1579Y	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	S1580A	Neutral	0.044
NOTCH3	Q9UM47-1.2	S1580C	Neutral	0.482
NOTCH3	Q9UM47-1.2	S1580D	Neutral	0.167
NOTCH3	Q9UM47-1.2	S1580E	Neutral	0.157
NOTCH3	Q9UM47-1.2	S1580F	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	S1580G	Neutral	0.162
NOTCH3	Q9UM47-1.2	S1580H	Neutral	0.45
NOTCH3	Q9UM47-1.2	S1580I	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	S1580K	Neutral	0.145
NOTCH3	Q9UM47-1.2	S1580L	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	S1580M	Neutral	0.446
NOTCH3	Q9UM47-1.2	S1580N	Neutral	0.041
NOTCH3	Q9UM47-1.2	S1580P	Neutral	0.478
NOTCH3	Q9UM47-1.2	S1580Q	Neutral	0.154
NOTCH3	Q9UM47-1.2	S1580R	Neutral	0.423
NOTCH3	Q9UM47-1.2	S1580T	Neutral	0.042
NOTCH3	Q9UM47-1.2	S1580V	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	S1580W	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	S1580Y	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	V1581A	Neutral	0.015
NOTCH3	Q9UM47-1.2	V1581C	Neutral	0.07
NOTCH3	Q9UM47-1.2	V1581D	Pathogenic	0.618
NOTCH3	Q9UM47-1.2	V1581E	Neutral	0.27
NOTCH3	Q9UM47-1.2	V1581F	Neutral	0.068
NOTCH3	Q9UM47-1.2	V1581G	Pathogenic	0.577
NOTCH3	Q9UM47-1.2	V1581H	Pathogenic	0.617
NOTCH3	Q9UM47-1.2	V1581I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V1581K	Neutral	0.251
NOTCH3	Q9UM47-1.2	V1581L	Neutral	0.004
NOTCH3	Q9UM47-1.2	V1581M	Neutral	0.004
NOTCH3	Q9UM47-1.2	V1581N	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	V1581P	Neutral	0.259
NOTCH3	Q9UM47-1.2	V1581Q	Neutral	0.265
NOTCH3	Q9UM47-1.2	V1581R	Pathogenic	0.592
NOTCH3	Q9UM47-1.2	V1581S	Neutral	0.248
NOTCH3	Q9UM47-1.2	V1581T	Neutral	0.017
NOTCH3	Q9UM47-1.2	V1581W	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	V1581Y	Neutral	0.066
NOTCH3	Q9UM47-1.2	V1582A	Neutral	0.427
NOTCH3	Q9UM47-1.2	V1582C	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	V1582D	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	V1582E	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	V1582F	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	V1582G	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	V1582H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	V1582I	Neutral	0.008
NOTCH3	Q9UM47-1.2	V1582K	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	V1582L	Neutral	0.149
NOTCH3	Q9UM47-1.2	V1582M	Neutral	0.149
NOTCH3	Q9UM47-1.2	V1582N	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	V1582P	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	V1582Q	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	V1582R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	V1582S	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	V1582T	Neutral	0.452
NOTCH3	Q9UM47-1.2	V1582W	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	V1582Y	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	M1583A	Neutral	0.197
NOTCH3	Q9UM47-1.2	M1583C	Neutral	0.207
NOTCH3	Q9UM47-1.2	M1583D	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	M1583E	Pathogenic	0.569
NOTCH3	Q9UM47-1.2	M1583F	Neutral	0.06
NOTCH3	Q9UM47-1.2	M1583G	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	M1583H	Pathogenic	0.576
NOTCH3	Q9UM47-1.2	M1583I	Neutral	0.014
NOTCH3	Q9UM47-1.2	M1583K	Neutral	0.228
NOTCH3	Q9UM47-1.2	M1583L	Neutral	0.003
NOTCH3	Q9UM47-1.2	M1583N	Pathogenic	0.556
NOTCH3	Q9UM47-1.2	M1583P	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	M1583Q	Neutral	0.061
NOTCH3	Q9UM47-1.2	M1583R	Neutral	0.219
NOTCH3	Q9UM47-1.2	M1583S	Neutral	0.201
NOTCH3	Q9UM47-1.2	M1583T	Neutral	0.213
NOTCH3	Q9UM47-1.2	M1583V	Neutral	0.013
NOTCH3	Q9UM47-1.2	M1583W	Neutral	0.208
NOTCH3	Q9UM47-1.2	M1583Y	Neutral	0.221
NOTCH3	Q9UM47-1.2	L1584A	Pathogenic	0.649
NOTCH3	Q9UM47-1.2	L1584C	Pathogenic	0.664
NOTCH3	Q9UM47-1.2	L1584D	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1584E	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	L1584F	Neutral	0.324
NOTCH3	Q9UM47-1.2	L1584G	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	L1584H	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	L1584I	Neutral	0.024
NOTCH3	Q9UM47-1.2	L1584K	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	L1584M	Neutral	0.024
NOTCH3	Q9UM47-1.2	L1584N	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	L1584P	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	L1584Q	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	L1584R	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	L1584S	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	L1584T	Pathogenic	0.671
NOTCH3	Q9UM47-1.2	L1584V	Neutral	0.093
NOTCH3	Q9UM47-1.2	L1584W	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	L1584Y	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	E1585A	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	E1585C	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	E1585D	Neutral	0.036
NOTCH3	Q9UM47-1.2	E1585F	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	E1585G	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	E1585H	Neutral	0.447
NOTCH3	Q9UM47-1.2	E1585I	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	E1585K	Neutral	0.142
NOTCH3	Q9UM47-1.2	E1585L	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	E1585M	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	E1585N	Neutral	0.442
NOTCH3	Q9UM47-1.2	E1585P	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	E1585Q	Neutral	0.038
NOTCH3	Q9UM47-1.2	E1585R	Neutral	0.418
NOTCH3	Q9UM47-1.2	E1585S	Neutral	0.421
NOTCH3	Q9UM47-1.2	E1585T	Pathogenic	0.782
NOTCH3	Q9UM47-1.2	E1585V	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	E1585W	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	E1585Y	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	I1586A	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	I1586C	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	I1586D	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	I1586E	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	I1586F	Pathogenic	0.638
NOTCH3	Q9UM47-1.2	I1586G	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	I1586H	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	I1586K	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	I1586L	Neutral	0.081
NOTCH3	Q9UM47-1.2	I1586M	Neutral	0.288
NOTCH3	Q9UM47-1.2	I1586N	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	I1586P	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	I1586Q	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	I1586R	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	I1586S	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	I1586T	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	I1586V	Neutral	0.018
NOTCH3	Q9UM47-1.2	I1586W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	I1586Y	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	D1587A	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	D1587C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D1587E	Neutral	0.032
NOTCH3	Q9UM47-1.2	D1587F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1587G	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	D1587H	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	D1587I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1587K	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	D1587L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1587M	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1587N	Neutral	0.137
NOTCH3	Q9UM47-1.2	D1587P	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	D1587Q	Neutral	0.403
NOTCH3	Q9UM47-1.2	D1587R	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	D1587S	Neutral	0.408
NOTCH3	Q9UM47-1.2	D1587T	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	D1587V	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1587W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1587Y	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	N1588A	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	N1588C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N1588D	Neutral	0.146
NOTCH3	Q9UM47-1.2	N1588E	Neutral	0.429
NOTCH3	Q9UM47-1.2	N1588F	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N1588G	Neutral	0.398
NOTCH3	Q9UM47-1.2	N1588H	Neutral	0.138
NOTCH3	Q9UM47-1.2	N1588I	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N1588K	Neutral	0.406
NOTCH3	Q9UM47-1.2	N1588L	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N1588M	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	N1588P	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	N1588Q	Neutral	0.425
NOTCH3	Q9UM47-1.2	N1588R	Neutral	0.394
NOTCH3	Q9UM47-1.2	N1588S	Neutral	0.138
NOTCH3	Q9UM47-1.2	N1588T	Neutral	0.44
NOTCH3	Q9UM47-1.2	N1588V	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	N1588W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N1588Y	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	R1589A	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	R1589C	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	R1589D	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	R1589E	Pathogenic	0.534
NOTCH3	Q9UM47-1.2	R1589F	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1589G	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	R1589H	Pathogenic	0.544
NOTCH3	Q9UM47-1.2	R1589I	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1589K	Neutral	0.057
NOTCH3	Q9UM47-1.2	R1589L	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	R1589M	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	R1589N	Pathogenic	0.522
NOTCH3	Q9UM47-1.2	R1589P	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	R1589Q	Neutral	0.205
NOTCH3	Q9UM47-1.2	R1589S	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	R1589T	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	R1589V	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	R1589W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1589Y	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	L1590A	Neutral	0.042
NOTCH3	Q9UM47-1.2	L1590C	Neutral	0.045
NOTCH3	Q9UM47-1.2	L1590D	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	L1590E	Pathogenic	0.521
NOTCH3	Q9UM47-1.2	L1590F	Neutral	0.011
NOTCH3	Q9UM47-1.2	L1590G	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	L1590H	Pathogenic	0.528
NOTCH3	Q9UM47-1.2	L1590I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1590K	Neutral	0.195
NOTCH3	Q9UM47-1.2	L1590M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1590N	Pathogenic	0.508
NOTCH3	Q9UM47-1.2	L1590P	Neutral	0.5
NOTCH3	Q9UM47-1.2	L1590Q	Neutral	0.195
NOTCH3	Q9UM47-1.2	L1590R	Neutral	0.188
NOTCH3	Q9UM47-1.2	L1590S	Neutral	0.171
NOTCH3	Q9UM47-1.2	L1590T	Neutral	0.047
NOTCH3	Q9UM47-1.2	L1590V	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1590W	Neutral	0.176
NOTCH3	Q9UM47-1.2	L1590Y	Neutral	0.049
NOTCH3	Q9UM47-1.2	C1591A	Neutral	0.233
NOTCH3	Q9UM47-1.2	C1591D	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	C1591E	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	C1591F	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	C1591G	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	C1591H	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	C1591I	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	C1591K	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	C1591L	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	C1591M	Pathogenic	0.562
NOTCH3	Q9UM47-1.2	C1591N	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	C1591P	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	C1591Q	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	C1591R	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	C1591S	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	C1591T	Pathogenic	0.592
NOTCH3	Q9UM47-1.2	C1591V	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	C1591W	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	C1591Y	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	L1592A	Neutral	0.009
NOTCH3	Q9UM47-1.2	L1592C	Neutral	0.01
NOTCH3	Q9UM47-1.2	L1592D	Neutral	0.483
NOTCH3	Q9UM47-1.2	L1592E	Neutral	0.18
NOTCH3	Q9UM47-1.2	L1592F	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1592G	Neutral	0.441
NOTCH3	Q9UM47-1.2	L1592H	Neutral	0.185
NOTCH3	Q9UM47-1.2	L1592I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1592K	Neutral	0.047
NOTCH3	Q9UM47-1.2	L1592M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1592N	Neutral	0.173
NOTCH3	Q9UM47-1.2	L1592P	Neutral	0.168
NOTCH3	Q9UM47-1.2	L1592Q	Neutral	0.047
NOTCH3	Q9UM47-1.2	L1592R	Neutral	0.045
NOTCH3	Q9UM47-1.2	L1592S	Neutral	0.04
NOTCH3	Q9UM47-1.2	L1592T	Neutral	0.01
NOTCH3	Q9UM47-1.2	L1592V	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1592W	Neutral	0.042
NOTCH3	Q9UM47-1.2	L1592Y	Neutral	0.01
NOTCH3	Q9UM47-1.2	Q1593A	Neutral	0.438
NOTCH3	Q9UM47-1.2	Q1593C	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	Q1593D	Neutral	0.158
NOTCH3	Q9UM47-1.2	Q1593E	Neutral	0.01
NOTCH3	Q9UM47-1.2	Q1593F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	Q1593G	Pathogenic	0.767
NOTCH3	Q9UM47-1.2	Q1593H	Neutral	0.168
NOTCH3	Q9UM47-1.2	Q1593I	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	Q1593K	Neutral	0.04
NOTCH3	Q9UM47-1.2	Q1593L	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	Q1593M	Neutral	0.166
NOTCH3	Q9UM47-1.2	Q1593N	Neutral	0.16
NOTCH3	Q9UM47-1.2	Q1593P	Neutral	0.461
NOTCH3	Q9UM47-1.2	Q1593R	Neutral	0.038
NOTCH3	Q9UM47-1.2	Q1593S	Neutral	0.149
NOTCH3	Q9UM47-1.2	Q1593T	Neutral	0.463
NOTCH3	Q9UM47-1.2	Q1593V	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	Q1593W	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	Q1593Y	Neutral	0.458
NOTCH3	Q9UM47-1.2	S1594A	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1594C	Neutral	0.048
NOTCH3	Q9UM47-1.2	S1594D	Neutral	0.011
NOTCH3	Q9UM47-1.2	S1594E	Neutral	0.01
NOTCH3	Q9UM47-1.2	S1594F	Neutral	0.16
NOTCH3	Q9UM47-1.2	S1594G	Neutral	0.01
NOTCH3	Q9UM47-1.2	S1594H	Neutral	0.042
NOTCH3	Q9UM47-1.2	S1594I	Neutral	0.166
NOTCH3	Q9UM47-1.2	S1594K	Neutral	0.009
NOTCH3	Q9UM47-1.2	S1594L	Neutral	0.166
NOTCH3	Q9UM47-1.2	S1594M	Neutral	0.042
NOTCH3	Q9UM47-1.2	S1594N	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1594P	Neutral	0.047
NOTCH3	Q9UM47-1.2	S1594Q	Neutral	0.01
NOTCH3	Q9UM47-1.2	S1594R	Neutral	0.038
NOTCH3	Q9UM47-1.2	S1594T	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1594V	Neutral	0.176
NOTCH3	Q9UM47-1.2	S1594W	Neutral	0.439
NOTCH3	Q9UM47-1.2	S1594Y	Neutral	0.156
NOTCH3	Q9UM47-1.2	P1595A	Neutral	0.028
NOTCH3	Q9UM47-1.2	P1595C	Neutral	0.395
NOTCH3	Q9UM47-1.2	P1595D	Neutral	0.031
NOTCH3	Q9UM47-1.2	P1595E	Neutral	0.029
NOTCH3	Q9UM47-1.2	P1595F	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	P1595G	Neutral	0.111
NOTCH3	Q9UM47-1.2	P1595H	Neutral	0.116
NOTCH3	Q9UM47-1.2	P1595I	Neutral	0.369
NOTCH3	Q9UM47-1.2	P1595K	Neutral	0.027
NOTCH3	Q9UM47-1.2	P1595L	Neutral	0.369
NOTCH3	Q9UM47-1.2	P1595M	Neutral	0.114
NOTCH3	Q9UM47-1.2	P1595N	Neutral	0.126
NOTCH3	Q9UM47-1.2	P1595Q	Neutral	0.029
NOTCH3	Q9UM47-1.2	P1595R	Neutral	0.105
NOTCH3	Q9UM47-1.2	P1595S	Neutral	0.029
NOTCH3	Q9UM47-1.2	P1595T	Neutral	0.031
NOTCH3	Q9UM47-1.2	P1595V	Neutral	0.121
NOTCH3	Q9UM47-1.2	P1595W	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	P1595Y	Neutral	0.353
NOTCH3	Q9UM47-1.2	E1596A	Neutral	0.068
NOTCH3	Q9UM47-1.2	E1596C	Pathogenic	0.882
NOTCH3	Q9UM47-1.2	E1596D	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1596F	Pathogenic	0.62
NOTCH3	Q9UM47-1.2	E1596G	Neutral	0.236
NOTCH3	Q9UM47-1.2	E1596H	Neutral	0.018
NOTCH3	Q9UM47-1.2	E1596I	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	E1596K	Neutral	0.004
NOTCH3	Q9UM47-1.2	E1596L	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	E1596M	Neutral	0.271
NOTCH3	Q9UM47-1.2	E1596N	Neutral	0.018
NOTCH3	Q9UM47-1.2	E1596P	Neutral	0.074
NOTCH3	Q9UM47-1.2	E1596Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1596R	Neutral	0.016
NOTCH3	Q9UM47-1.2	E1596S	Neutral	0.016
NOTCH3	Q9UM47-1.2	E1596T	Neutral	0.075
NOTCH3	Q9UM47-1.2	E1596V	Neutral	0.28
NOTCH3	Q9UM47-1.2	E1596W	Pathogenic	0.595
NOTCH3	Q9UM47-1.2	E1596Y	Neutral	0.258
NOTCH3	Q9UM47-1.2	N1597A	Neutral	0.11
NOTCH3	Q9UM47-1.2	N1597C	Neutral	0.377
NOTCH3	Q9UM47-1.2	N1597D	Neutral	0.001
NOTCH3	Q9UM47-1.2	N1597E	Neutral	0.006
NOTCH3	Q9UM47-1.2	N1597F	Neutral	0.353
NOTCH3	Q9UM47-1.2	N1597G	Neutral	0.005
NOTCH3	Q9UM47-1.2	N1597H	Neutral	0.001
NOTCH3	Q9UM47-1.2	N1597I	Neutral	0.363
NOTCH3	Q9UM47-1.2	N1597K	Neutral	0.006
NOTCH3	Q9UM47-1.2	N1597L	Neutral	0.362
NOTCH3	Q9UM47-1.2	N1597M	Neutral	0.111
NOTCH3	Q9UM47-1.2	N1597P	Neutral	0.119
NOTCH3	Q9UM47-1.2	N1597Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	N1597R	Neutral	0.005
NOTCH3	Q9UM47-1.2	N1597S	Neutral	0.001
NOTCH3	Q9UM47-1.2	N1597T	Neutral	0.007
NOTCH3	Q9UM47-1.2	N1597V	Neutral	0.379
NOTCH3	Q9UM47-1.2	N1597W	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	N1597Y	Neutral	0.104
NOTCH3	Q9UM47-1.2	D1598A	Neutral	0.273
NOTCH3	Q9UM47-1.2	D1598C	Pathogenic	0.649
NOTCH3	Q9UM47-1.2	D1598E	Neutral	0.001
NOTCH3	Q9UM47-1.2	D1598F	Pathogenic	0.616
NOTCH3	Q9UM47-1.2	D1598G	Neutral	0.071
NOTCH3	Q9UM47-1.2	D1598H	Neutral	0.075
NOTCH3	Q9UM47-1.2	D1598I	Pathogenic	0.626
NOTCH3	Q9UM47-1.2	D1598K	Neutral	0.071
NOTCH3	Q9UM47-1.2	D1598L	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	D1598M	Pathogenic	0.625
NOTCH3	Q9UM47-1.2	D1598N	Neutral	0.004
NOTCH3	Q9UM47-1.2	D1598P	Neutral	0.083
NOTCH3	Q9UM47-1.2	D1598Q	Neutral	0.018
NOTCH3	Q9UM47-1.2	D1598R	Neutral	0.247
NOTCH3	Q9UM47-1.2	D1598S	Neutral	0.018
NOTCH3	Q9UM47-1.2	D1598T	Neutral	0.082
NOTCH3	Q9UM47-1.2	D1598V	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	D1598W	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	D1598Y	Pathogenic	0.609
NOTCH3	Q9UM47-1.2	H1599A	Neutral	0.283
NOTCH3	Q9UM47-1.2	H1599C	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	H1599D	Neutral	0.087
NOTCH3	Q9UM47-1.2	H1599E	Neutral	0.022
NOTCH3	Q9UM47-1.2	H1599F	Neutral	0.091
NOTCH3	Q9UM47-1.2	H1599G	Neutral	0.268
NOTCH3	Q9UM47-1.2	H1599I	Pathogenic	0.684
NOTCH3	Q9UM47-1.2	H1599K	Neutral	0.091
NOTCH3	Q9UM47-1.2	H1599L	Pathogenic	0.684
NOTCH3	Q9UM47-1.2	H1599M	Neutral	0.321
NOTCH3	Q9UM47-1.2	H1599N	Neutral	0.005
NOTCH3	Q9UM47-1.2	H1599P	Neutral	0.302
NOTCH3	Q9UM47-1.2	H1599Q	Neutral	0.022
NOTCH3	Q9UM47-1.2	H1599R	Neutral	0.02
NOTCH3	Q9UM47-1.2	H1599S	Neutral	0.081
NOTCH3	Q9UM47-1.2	H1599T	Neutral	0.304
NOTCH3	Q9UM47-1.2	H1599V	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	H1599W	Neutral	0.291
NOTCH3	Q9UM47-1.2	H1599Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	C1600A	Neutral	0.233
NOTCH3	Q9UM47-1.2	C1600D	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	C1600E	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	C1600F	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	C1600G	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	C1600H	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	C1600I	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	C1600K	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	C1600L	Pathogenic	0.562
NOTCH3	Q9UM47-1.2	C1600M	Pathogenic	0.561
NOTCH3	Q9UM47-1.2	C1600N	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	C1600P	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	C1600Q	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	C1600R	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	C1600S	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	C1600T	Pathogenic	0.592
NOTCH3	Q9UM47-1.2	C1600V	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	C1600W	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	C1600Y	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	F1601A	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	F1601C	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	F1601D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F1601E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1601G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F1601H	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	F1601I	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	F1601K	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1601L	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	F1601M	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	F1601N	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1601P	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	F1601Q	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1601R	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1601S	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	F1601T	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	F1601V	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	F1601W	Neutral	0.409
NOTCH3	Q9UM47-1.2	F1601Y	Neutral	0.035
NOTCH3	Q9UM47-1.2	P1602A	Neutral	0.02
NOTCH3	Q9UM47-1.2	P1602C	Neutral	0.313
NOTCH3	Q9UM47-1.2	P1602D	Neutral	0.022
NOTCH3	Q9UM47-1.2	P1602E	Neutral	0.021
NOTCH3	Q9UM47-1.2	P1602F	Pathogenic	0.641
NOTCH3	Q9UM47-1.2	P1602G	Neutral	0.08
NOTCH3	Q9UM47-1.2	P1602H	Neutral	0.084
NOTCH3	Q9UM47-1.2	P1602I	Neutral	0.29
NOTCH3	Q9UM47-1.2	P1602K	Neutral	0.019
NOTCH3	Q9UM47-1.2	P1602L	Neutral	0.29
NOTCH3	Q9UM47-1.2	P1602M	Neutral	0.082
NOTCH3	Q9UM47-1.2	P1602N	Neutral	0.091
NOTCH3	Q9UM47-1.2	P1602Q	Neutral	0.02
NOTCH3	Q9UM47-1.2	P1602R	Neutral	0.076
NOTCH3	Q9UM47-1.2	P1602S	Neutral	0.021
NOTCH3	Q9UM47-1.2	P1602T	Neutral	0.022
NOTCH3	Q9UM47-1.2	P1602V	Neutral	0.088
NOTCH3	Q9UM47-1.2	P1602W	Pathogenic	0.617
NOTCH3	Q9UM47-1.2	P1602Y	Neutral	0.276
NOTCH3	Q9UM47-1.2	D1603A	Neutral	0.106
NOTCH3	Q9UM47-1.2	D1603C	Neutral	0.369
NOTCH3	Q9UM47-1.2	D1603E	Neutral	0.0
NOTCH3	Q9UM47-1.2	D1603F	Neutral	0.337
NOTCH3	Q9UM47-1.2	D1603G	Neutral	0.024
NOTCH3	Q9UM47-1.2	D1603H	Neutral	0.025
NOTCH3	Q9UM47-1.2	D1603I	Neutral	0.346
NOTCH3	Q9UM47-1.2	D1603K	Neutral	0.023
NOTCH3	Q9UM47-1.2	D1603L	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	D1603M	Neutral	0.345
NOTCH3	Q9UM47-1.2	D1603N	Neutral	0.001
NOTCH3	Q9UM47-1.2	D1603P	Neutral	0.028
NOTCH3	Q9UM47-1.2	D1603Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	D1603R	Neutral	0.094
NOTCH3	Q9UM47-1.2	D1603S	Neutral	0.006
NOTCH3	Q9UM47-1.2	D1603T	Neutral	0.028
NOTCH3	Q9UM47-1.2	D1603V	Neutral	0.362
NOTCH3	Q9UM47-1.2	D1603W	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	D1603Y	Neutral	0.33
NOTCH3	Q9UM47-1.2	A1604C	Neutral	0.097
NOTCH3	Q9UM47-1.2	A1604D	Pathogenic	0.686
NOTCH3	Q9UM47-1.2	A1604E	Neutral	0.31
NOTCH3	Q9UM47-1.2	A1604F	Pathogenic	0.65
NOTCH3	Q9UM47-1.2	A1604G	Neutral	0.097
NOTCH3	Q9UM47-1.2	A1604H	Pathogenic	0.662
NOTCH3	Q9UM47-1.2	A1604I	Neutral	0.298
NOTCH3	Q9UM47-1.2	A1604K	Neutral	0.289
NOTCH3	Q9UM47-1.2	A1604L	Neutral	0.298
NOTCH3	Q9UM47-1.2	A1604M	Neutral	0.297
NOTCH3	Q9UM47-1.2	A1604N	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	A1604P	Neutral	0.324
NOTCH3	Q9UM47-1.2	A1604Q	Neutral	0.305
NOTCH3	Q9UM47-1.2	A1604R	Neutral	0.279
NOTCH3	Q9UM47-1.2	A1604S	Neutral	0.024
NOTCH3	Q9UM47-1.2	A1604T	Neutral	0.094
NOTCH3	Q9UM47-1.2	A1604V	Neutral	0.091
NOTCH3	Q9UM47-1.2	A1604W	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	A1604Y	Pathogenic	0.643
NOTCH3	Q9UM47-1.2	Q1605A	Neutral	0.02
NOTCH3	Q9UM47-1.2	Q1605C	Neutral	0.318
NOTCH3	Q9UM47-1.2	Q1605D	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q1605E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1605F	Neutral	0.325
NOTCH3	Q9UM47-1.2	Q1605G	Neutral	0.081
NOTCH3	Q9UM47-1.2	Q1605H	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q1605I	Neutral	0.334
NOTCH3	Q9UM47-1.2	Q1605K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1605L	Neutral	0.099
NOTCH3	Q9UM47-1.2	Q1605M	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q1605N	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q1605P	Neutral	0.022
NOTCH3	Q9UM47-1.2	Q1605R	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q1605S	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q1605T	Neutral	0.022
NOTCH3	Q9UM47-1.2	Q1605V	Neutral	0.099
NOTCH3	Q9UM47-1.2	Q1605W	Neutral	0.087
NOTCH3	Q9UM47-1.2	Q1605Y	Neutral	0.022
NOTCH3	Q9UM47-1.2	S1606A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1606C	Neutral	0.021
NOTCH3	Q9UM47-1.2	S1606D	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1606E	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1606F	Neutral	0.075
NOTCH3	Q9UM47-1.2	S1606G	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1606H	Neutral	0.018
NOTCH3	Q9UM47-1.2	S1606I	Neutral	0.078
NOTCH3	Q9UM47-1.2	S1606K	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1606L	Neutral	0.078
NOTCH3	Q9UM47-1.2	S1606M	Neutral	0.018
NOTCH3	Q9UM47-1.2	S1606N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1606P	Neutral	0.021
NOTCH3	Q9UM47-1.2	S1606Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1606R	Neutral	0.017
NOTCH3	Q9UM47-1.2	S1606T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1606V	Neutral	0.083
NOTCH3	Q9UM47-1.2	S1606W	Neutral	0.25
NOTCH3	Q9UM47-1.2	S1606Y	Neutral	0.073
NOTCH3	Q9UM47-1.2	A1607C	Neutral	0.119
NOTCH3	Q9UM47-1.2	A1607D	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	A1607E	Neutral	0.36
NOTCH3	Q9UM47-1.2	A1607F	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	A1607G	Neutral	0.118
NOTCH3	Q9UM47-1.2	A1607H	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	A1607I	Neutral	0.348
NOTCH3	Q9UM47-1.2	A1607K	Neutral	0.338
NOTCH3	Q9UM47-1.2	A1607L	Neutral	0.347
NOTCH3	Q9UM47-1.2	A1607M	Neutral	0.346
NOTCH3	Q9UM47-1.2	A1607N	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	A1607P	Neutral	0.376
NOTCH3	Q9UM47-1.2	A1607Q	Neutral	0.355
NOTCH3	Q9UM47-1.2	A1607R	Neutral	0.327
NOTCH3	Q9UM47-1.2	A1607S	Neutral	0.03
NOTCH3	Q9UM47-1.2	A1607T	Neutral	0.115
NOTCH3	Q9UM47-1.2	A1607V	Neutral	0.111
NOTCH3	Q9UM47-1.2	A1607W	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	A1607Y	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	A1608C	Neutral	0.38
NOTCH3	Q9UM47-1.2	A1608D	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	A1608E	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	A1608F	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	A1608G	Neutral	0.379
NOTCH3	Q9UM47-1.2	A1608H	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	A1608I	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	A1608K	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	A1608L	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	A1608M	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	A1608N	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	A1608P	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	A1608Q	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	A1608R	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	A1608S	Neutral	0.124
NOTCH3	Q9UM47-1.2	A1608T	Neutral	0.373
NOTCH3	Q9UM47-1.2	A1608V	Neutral	0.363
NOTCH3	Q9UM47-1.2	A1608W	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	A1608Y	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	D1609A	Neutral	0.15
NOTCH3	Q9UM47-1.2	D1609C	Neutral	0.465
NOTCH3	Q9UM47-1.2	D1609E	Neutral	0.0
NOTCH3	Q9UM47-1.2	D1609F	Neutral	0.429
NOTCH3	Q9UM47-1.2	D1609G	Neutral	0.035
NOTCH3	Q9UM47-1.2	D1609H	Neutral	0.037
NOTCH3	Q9UM47-1.2	D1609I	Neutral	0.44
NOTCH3	Q9UM47-1.2	D1609K	Neutral	0.034
NOTCH3	Q9UM47-1.2	D1609L	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	D1609M	Neutral	0.439
NOTCH3	Q9UM47-1.2	D1609N	Neutral	0.002
NOTCH3	Q9UM47-1.2	D1609P	Neutral	0.041
NOTCH3	Q9UM47-1.2	D1609Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	D1609R	Neutral	0.134
NOTCH3	Q9UM47-1.2	D1609S	Neutral	0.009
NOTCH3	Q9UM47-1.2	D1609T	Neutral	0.04
NOTCH3	Q9UM47-1.2	D1609V	Neutral	0.457
NOTCH3	Q9UM47-1.2	D1609W	Pathogenic	0.755
NOTCH3	Q9UM47-1.2	D1609Y	Neutral	0.422
NOTCH3	Q9UM47-1.2	Y1610A	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	Y1610C	Pathogenic	0.638
NOTCH3	Q9UM47-1.2	Y1610D	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	Y1610E	Pathogenic	0.662
NOTCH3	Q9UM47-1.2	Y1610F	Neutral	0.001
NOTCH3	Q9UM47-1.2	Y1610G	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	Y1610H	Neutral	0.005
NOTCH3	Q9UM47-1.2	Y1610I	Neutral	0.311
NOTCH3	Q9UM47-1.2	Y1610K	Pathogenic	0.684
NOTCH3	Q9UM47-1.2	Y1610L	Neutral	0.311
NOTCH3	Q9UM47-1.2	Y1610M	Neutral	0.31
NOTCH3	Q9UM47-1.2	Y1610N	Pathogenic	0.65
NOTCH3	Q9UM47-1.2	Y1610P	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	Y1610Q	Neutral	0.304
NOTCH3	Q9UM47-1.2	Y1610R	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	Y1610S	Pathogenic	0.629
NOTCH3	Q9UM47-1.2	Y1610T	Pathogenic	0.646
NOTCH3	Q9UM47-1.2	Y1610V	Neutral	0.295
NOTCH3	Q9UM47-1.2	Y1610W	Neutral	0.005
NOTCH3	Q9UM47-1.2	L1611A	Pathogenic	0.613
NOTCH3	Q9UM47-1.2	L1611C	Pathogenic	0.629
NOTCH3	Q9UM47-1.2	L1611D	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	L1611E	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	L1611F	Neutral	0.291
NOTCH3	Q9UM47-1.2	L1611G	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	L1611H	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	L1611I	Neutral	0.02
NOTCH3	Q9UM47-1.2	L1611K	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	L1611M	Neutral	0.02
NOTCH3	Q9UM47-1.2	L1611N	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	L1611P	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	L1611Q	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	L1611R	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	L1611S	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	L1611T	Pathogenic	0.636
NOTCH3	Q9UM47-1.2	L1611V	Neutral	0.081
NOTCH3	Q9UM47-1.2	L1611W	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	L1611Y	Pathogenic	0.648
NOTCH3	Q9UM47-1.2	G1612A	Neutral	0.049
NOTCH3	Q9UM47-1.2	G1612C	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	G1612D	Neutral	0.176
NOTCH3	Q9UM47-1.2	G1612E	Neutral	0.475
NOTCH3	Q9UM47-1.2	G1612F	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	G1612H	Neutral	0.465
NOTCH3	Q9UM47-1.2	G1612I	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	G1612K	Neutral	0.451
NOTCH3	Q9UM47-1.2	G1612L	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	G1612M	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	G1612N	Neutral	0.044
NOTCH3	Q9UM47-1.2	G1612P	Neutral	0.493
NOTCH3	Q9UM47-1.2	G1612Q	Neutral	0.469
NOTCH3	Q9UM47-1.2	G1612R	Neutral	0.438
NOTCH3	Q9UM47-1.2	G1612S	Neutral	0.048
NOTCH3	Q9UM47-1.2	G1612T	Neutral	0.49
NOTCH3	Q9UM47-1.2	G1612V	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	G1612W	Neutral	0.427
NOTCH3	Q9UM47-1.2	G1612Y	Pathogenic	0.785
NOTCH3	Q9UM47-1.2	A1613C	Neutral	0.212
NOTCH3	Q9UM47-1.2	A1613D	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	A1613E	Pathogenic	0.529
NOTCH3	Q9UM47-1.2	A1613F	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	A1613G	Neutral	0.212
NOTCH3	Q9UM47-1.2	A1613H	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	A1613I	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	A1613K	Pathogenic	0.505
NOTCH3	Q9UM47-1.2	A1613L	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	A1613M	Pathogenic	0.515
NOTCH3	Q9UM47-1.2	A1613N	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	A1613P	Pathogenic	0.546
NOTCH3	Q9UM47-1.2	A1613Q	Pathogenic	0.524
NOTCH3	Q9UM47-1.2	A1613R	Neutral	0.493
NOTCH3	Q9UM47-1.2	A1613S	Neutral	0.058
NOTCH3	Q9UM47-1.2	A1613T	Neutral	0.207
NOTCH3	Q9UM47-1.2	A1613V	Neutral	0.201
NOTCH3	Q9UM47-1.2	A1613W	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	A1613Y	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	L1614A	Neutral	0.155
NOTCH3	Q9UM47-1.2	L1614C	Neutral	0.164
NOTCH3	Q9UM47-1.2	L1614D	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	L1614E	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	L1614F	Neutral	0.045
NOTCH3	Q9UM47-1.2	L1614G	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	L1614H	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	L1614I	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1614K	Pathogenic	0.501
NOTCH3	Q9UM47-1.2	L1614M	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1614N	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	L1614P	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	L1614Q	Pathogenic	0.5
NOTCH3	Q9UM47-1.2	L1614R	Neutral	0.489
NOTCH3	Q9UM47-1.2	L1614S	Neutral	0.461
NOTCH3	Q9UM47-1.2	L1614T	Neutral	0.168
NOTCH3	Q9UM47-1.2	L1614V	Neutral	0.01
NOTCH3	Q9UM47-1.2	L1614W	Neutral	0.47
NOTCH3	Q9UM47-1.2	L1614Y	Neutral	0.175
NOTCH3	Q9UM47-1.2	S1615A	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1615C	Neutral	0.047
NOTCH3	Q9UM47-1.2	S1615D	Neutral	0.01
NOTCH3	Q9UM47-1.2	S1615E	Neutral	0.01
NOTCH3	Q9UM47-1.2	S1615F	Neutral	0.157
NOTCH3	Q9UM47-1.2	S1615G	Neutral	0.01
NOTCH3	Q9UM47-1.2	S1615H	Neutral	0.041
NOTCH3	Q9UM47-1.2	S1615I	Neutral	0.162
NOTCH3	Q9UM47-1.2	S1615K	Neutral	0.009
NOTCH3	Q9UM47-1.2	S1615L	Neutral	0.162
NOTCH3	Q9UM47-1.2	S1615M	Neutral	0.041
NOTCH3	Q9UM47-1.2	S1615N	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1615P	Neutral	0.046
NOTCH3	Q9UM47-1.2	S1615Q	Neutral	0.01
NOTCH3	Q9UM47-1.2	S1615R	Neutral	0.037
NOTCH3	Q9UM47-1.2	S1615T	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1615V	Neutral	0.172
NOTCH3	Q9UM47-1.2	S1615W	Neutral	0.433
NOTCH3	Q9UM47-1.2	S1615Y	Neutral	0.153
NOTCH3	Q9UM47-1.2	A1616C	Neutral	0.009
NOTCH3	Q9UM47-1.2	A1616D	Neutral	0.157
NOTCH3	Q9UM47-1.2	A1616E	Neutral	0.037
NOTCH3	Q9UM47-1.2	A1616F	Neutral	0.137
NOTCH3	Q9UM47-1.2	A1616G	Neutral	0.009
NOTCH3	Q9UM47-1.2	A1616H	Neutral	0.143
NOTCH3	Q9UM47-1.2	A1616I	Neutral	0.035
NOTCH3	Q9UM47-1.2	A1616K	Neutral	0.034
NOTCH3	Q9UM47-1.2	A1616L	Neutral	0.035
NOTCH3	Q9UM47-1.2	A1616M	Neutral	0.035
NOTCH3	Q9UM47-1.2	A1616N	Neutral	0.155
NOTCH3	Q9UM47-1.2	A1616P	Neutral	0.039
NOTCH3	Q9UM47-1.2	A1616Q	Neutral	0.036
NOTCH3	Q9UM47-1.2	A1616R	Neutral	0.032
NOTCH3	Q9UM47-1.2	A1616S	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1616T	Neutral	0.009
NOTCH3	Q9UM47-1.2	A1616V	Neutral	0.008
NOTCH3	Q9UM47-1.2	A1616W	Neutral	0.393
NOTCH3	Q9UM47-1.2	A1616Y	Neutral	0.133
NOTCH3	Q9UM47-1.2	V1617A	Neutral	0.006
NOTCH3	Q9UM47-1.2	V1617C	Neutral	0.03
NOTCH3	Q9UM47-1.2	V1617D	Neutral	0.397
NOTCH3	Q9UM47-1.2	V1617E	Neutral	0.131
NOTCH3	Q9UM47-1.2	V1617F	Neutral	0.029
NOTCH3	Q9UM47-1.2	V1617G	Neutral	0.357
NOTCH3	Q9UM47-1.2	V1617H	Neutral	0.396
NOTCH3	Q9UM47-1.2	V1617I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V1617K	Neutral	0.12
NOTCH3	Q9UM47-1.2	V1617L	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1617M	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1617N	Neutral	0.401
NOTCH3	Q9UM47-1.2	V1617P	Neutral	0.125
NOTCH3	Q9UM47-1.2	V1617Q	Neutral	0.128
NOTCH3	Q9UM47-1.2	V1617R	Neutral	0.371
NOTCH3	Q9UM47-1.2	V1617S	Neutral	0.118
NOTCH3	Q9UM47-1.2	V1617T	Neutral	0.007
NOTCH3	Q9UM47-1.2	V1617W	Neutral	0.356
NOTCH3	Q9UM47-1.2	V1617Y	Neutral	0.028
NOTCH3	Q9UM47-1.2	E1618A	Neutral	0.051
NOTCH3	Q9UM47-1.2	E1618C	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	E1618D	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1618F	Pathogenic	0.543
NOTCH3	Q9UM47-1.2	E1618G	Neutral	0.184
NOTCH3	Q9UM47-1.2	E1618H	Neutral	0.013
NOTCH3	Q9UM47-1.2	E1618I	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	E1618K	Neutral	0.003
NOTCH3	Q9UM47-1.2	E1618L	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	E1618M	Neutral	0.214
NOTCH3	Q9UM47-1.2	E1618N	Neutral	0.013
NOTCH3	Q9UM47-1.2	E1618P	Neutral	0.055
NOTCH3	Q9UM47-1.2	E1618Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1618R	Neutral	0.012
NOTCH3	Q9UM47-1.2	E1618S	Neutral	0.012
NOTCH3	Q9UM47-1.2	E1618T	Neutral	0.056
NOTCH3	Q9UM47-1.2	E1618V	Neutral	0.221
NOTCH3	Q9UM47-1.2	E1618W	Pathogenic	0.518
NOTCH3	Q9UM47-1.2	E1618Y	Neutral	0.202
NOTCH3	Q9UM47-1.2	R1619A	Neutral	0.022
NOTCH3	Q9UM47-1.2	R1619C	Neutral	0.331
NOTCH3	Q9UM47-1.2	R1619D	Neutral	0.098
NOTCH3	Q9UM47-1.2	R1619E	Neutral	0.006
NOTCH3	Q9UM47-1.2	R1619F	Neutral	0.375
NOTCH3	Q9UM47-1.2	R1619G	Neutral	0.085
NOTCH3	Q9UM47-1.2	R1619H	Neutral	0.006
NOTCH3	Q9UM47-1.2	R1619I	Neutral	0.365
NOTCH3	Q9UM47-1.2	R1619K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R1619L	Neutral	0.112
NOTCH3	Q9UM47-1.2	R1619M	Neutral	0.027
NOTCH3	Q9UM47-1.2	R1619N	Neutral	0.005
NOTCH3	Q9UM47-1.2	R1619P	Neutral	0.099
NOTCH3	Q9UM47-1.2	R1619Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1619S	Neutral	0.022
NOTCH3	Q9UM47-1.2	R1619T	Neutral	0.024
NOTCH3	Q9UM47-1.2	R1619V	Neutral	0.348
NOTCH3	Q9UM47-1.2	R1619W	Neutral	0.374
NOTCH3	Q9UM47-1.2	R1619Y	Neutral	0.118
NOTCH3	Q9UM47-1.2	L1620A	Pathogenic	0.685
NOTCH3	Q9UM47-1.2	L1620C	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	L1620D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1620E	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1620F	Neutral	0.361
NOTCH3	Q9UM47-1.2	L1620G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1620H	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1620I	Neutral	0.028
NOTCH3	Q9UM47-1.2	L1620K	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	L1620M	Neutral	0.028
NOTCH3	Q9UM47-1.2	L1620N	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L1620P	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	L1620Q	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	L1620R	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	L1620S	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	L1620T	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	L1620V	Neutral	0.108
NOTCH3	Q9UM47-1.2	L1620W	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	L1620Y	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	D1621A	Neutral	0.113
NOTCH3	Q9UM47-1.2	D1621C	Neutral	0.385
NOTCH3	Q9UM47-1.2	D1621E	Neutral	0.0
NOTCH3	Q9UM47-1.2	D1621F	Neutral	0.352
NOTCH3	Q9UM47-1.2	D1621G	Neutral	0.025
NOTCH3	Q9UM47-1.2	D1621H	Neutral	0.027
NOTCH3	Q9UM47-1.2	D1621I	Neutral	0.362
NOTCH3	Q9UM47-1.2	D1621K	Neutral	0.025
NOTCH3	Q9UM47-1.2	D1621L	Pathogenic	0.72
NOTCH3	Q9UM47-1.2	D1621M	Neutral	0.361
NOTCH3	Q9UM47-1.2	D1621N	Neutral	0.001
NOTCH3	Q9UM47-1.2	D1621P	Neutral	0.03
NOTCH3	Q9UM47-1.2	D1621Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	D1621R	Neutral	0.1
NOTCH3	Q9UM47-1.2	D1621S	Neutral	0.006
NOTCH3	Q9UM47-1.2	D1621T	Neutral	0.03
NOTCH3	Q9UM47-1.2	D1621V	Neutral	0.378
NOTCH3	Q9UM47-1.2	D1621W	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	D1621Y	Neutral	0.345
NOTCH3	Q9UM47-1.2	F1622A	Neutral	0.351
NOTCH3	Q9UM47-1.2	F1622C	Neutral	0.367
NOTCH3	Q9UM47-1.2	F1622D	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	F1622E	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	F1622G	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	F1622H	Neutral	0.127
NOTCH3	Q9UM47-1.2	F1622I	Neutral	0.031
NOTCH3	Q9UM47-1.2	F1622K	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	F1622L	Neutral	0.031
NOTCH3	Q9UM47-1.2	F1622M	Neutral	0.031
NOTCH3	Q9UM47-1.2	F1622N	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	F1622P	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	F1622Q	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	F1622R	Pathogenic	0.755
NOTCH3	Q9UM47-1.2	F1622S	Neutral	0.357
NOTCH3	Q9UM47-1.2	F1622T	Neutral	0.374
NOTCH3	Q9UM47-1.2	F1622V	Neutral	0.12
NOTCH3	Q9UM47-1.2	F1622W	Neutral	0.007
NOTCH3	Q9UM47-1.2	F1622Y	Neutral	0.0
NOTCH3	Q9UM47-1.2	P1623A	Neutral	0.269
NOTCH3	Q9UM47-1.2	P1623C	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	P1623D	Neutral	0.288
NOTCH3	Q9UM47-1.2	P1623E	Neutral	0.274
NOTCH3	Q9UM47-1.2	P1623F	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	P1623G	Pathogenic	0.61
NOTCH3	Q9UM47-1.2	P1623H	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	P1623I	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	P1623K	Neutral	0.255
NOTCH3	Q9UM47-1.2	P1623L	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	P1623M	Pathogenic	0.617
NOTCH3	Q9UM47-1.2	P1623N	Pathogenic	0.644
NOTCH3	Q9UM47-1.2	P1623Q	Neutral	0.27
NOTCH3	Q9UM47-1.2	P1623R	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	P1623S	Neutral	0.275
NOTCH3	Q9UM47-1.2	P1623T	Neutral	0.285
NOTCH3	Q9UM47-1.2	P1623V	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	P1623W	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	P1623Y	Pathogenic	0.873
NOTCH3	Q9UM47-1.2	Y1624A	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	Y1624C	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	Y1624D	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	Y1624E	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	Y1624F	Neutral	0.022
NOTCH3	Q9UM47-1.2	Y1624G	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	Y1624H	Neutral	0.089
NOTCH3	Q9UM47-1.2	Y1624I	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	Y1624K	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	Y1624L	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	Y1624M	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	Y1624N	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	Y1624P	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	Y1624Q	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	Y1624R	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	Y1624S	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	Y1624T	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	Y1624V	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	Y1624W	Neutral	0.089
NOTCH3	Q9UM47-1.2	P1625A	Neutral	0.209
NOTCH3	Q9UM47-1.2	P1625C	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	P1625D	Neutral	0.225
NOTCH3	Q9UM47-1.2	P1625E	Neutral	0.213
NOTCH3	Q9UM47-1.2	P1625F	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	P1625G	Pathogenic	0.529
NOTCH3	Q9UM47-1.2	P1625H	Pathogenic	0.542
NOTCH3	Q9UM47-1.2	P1625I	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	P1625K	Neutral	0.197
NOTCH3	Q9UM47-1.2	P1625L	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	P1625M	Pathogenic	0.536
NOTCH3	Q9UM47-1.2	P1625N	Pathogenic	0.565
NOTCH3	Q9UM47-1.2	P1625Q	Neutral	0.21
NOTCH3	Q9UM47-1.2	P1625R	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	P1625S	Neutral	0.214
NOTCH3	Q9UM47-1.2	P1625T	Neutral	0.223
NOTCH3	Q9UM47-1.2	P1625V	Pathogenic	0.555
NOTCH3	Q9UM47-1.2	P1625W	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	P1625Y	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	L1626A	Neutral	0.162
NOTCH3	Q9UM47-1.2	L1626C	Neutral	0.172
NOTCH3	Q9UM47-1.2	L1626D	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	L1626E	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	L1626F	Neutral	0.048
NOTCH3	Q9UM47-1.2	L1626G	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	L1626H	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	L1626I	Neutral	0.003
NOTCH3	Q9UM47-1.2	L1626K	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	L1626M	Neutral	0.003
NOTCH3	Q9UM47-1.2	L1626N	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	L1626P	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	L1626Q	Pathogenic	0.515
NOTCH3	Q9UM47-1.2	L1626R	Pathogenic	0.503
NOTCH3	Q9UM47-1.2	L1626S	Neutral	0.475
NOTCH3	Q9UM47-1.2	L1626T	Neutral	0.176
NOTCH3	Q9UM47-1.2	L1626V	Neutral	0.011
NOTCH3	Q9UM47-1.2	L1626W	Neutral	0.484
NOTCH3	Q9UM47-1.2	L1626Y	Neutral	0.184
NOTCH3	Q9UM47-1.2	R1627A	Neutral	0.033
NOTCH3	Q9UM47-1.2	R1627C	Neutral	0.432
NOTCH3	Q9UM47-1.2	R1627D	Neutral	0.144
NOTCH3	Q9UM47-1.2	R1627E	Neutral	0.009
NOTCH3	Q9UM47-1.2	R1627F	Neutral	0.481
NOTCH3	Q9UM47-1.2	R1627G	Neutral	0.125
NOTCH3	Q9UM47-1.2	R1627H	Neutral	0.009
NOTCH3	Q9UM47-1.2	R1627I	Neutral	0.47
NOTCH3	Q9UM47-1.2	R1627K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R1627L	Neutral	0.163
NOTCH3	Q9UM47-1.2	R1627M	Neutral	0.041
NOTCH3	Q9UM47-1.2	R1627N	Neutral	0.008
NOTCH3	Q9UM47-1.2	R1627P	Neutral	0.145
NOTCH3	Q9UM47-1.2	R1627Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1627S	Neutral	0.034
NOTCH3	Q9UM47-1.2	R1627T	Neutral	0.036
NOTCH3	Q9UM47-1.2	R1627V	Neutral	0.451
NOTCH3	Q9UM47-1.2	R1627W	Neutral	0.48
NOTCH3	Q9UM47-1.2	R1627Y	Neutral	0.171
NOTCH3	Q9UM47-1.2	D1628A	Neutral	0.031
NOTCH3	Q9UM47-1.2	D1628C	Neutral	0.136
NOTCH3	Q9UM47-1.2	D1628E	Neutral	0.0
NOTCH3	Q9UM47-1.2	D1628F	Neutral	0.12
NOTCH3	Q9UM47-1.2	D1628G	Neutral	0.006
NOTCH3	Q9UM47-1.2	D1628H	Neutral	0.007
NOTCH3	Q9UM47-1.2	D1628I	Neutral	0.124
NOTCH3	Q9UM47-1.2	D1628K	Neutral	0.006
NOTCH3	Q9UM47-1.2	D1628L	Neutral	0.392
NOTCH3	Q9UM47-1.2	D1628M	Neutral	0.124
NOTCH3	Q9UM47-1.2	D1628N	Neutral	0.0
NOTCH3	Q9UM47-1.2	D1628P	Neutral	0.008
NOTCH3	Q9UM47-1.2	D1628Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	D1628R	Neutral	0.027
NOTCH3	Q9UM47-1.2	D1628S	Neutral	0.002
NOTCH3	Q9UM47-1.2	D1628T	Neutral	0.008
NOTCH3	Q9UM47-1.2	D1628V	Neutral	0.132
NOTCH3	Q9UM47-1.2	D1628W	Neutral	0.358
NOTCH3	Q9UM47-1.2	D1628Y	Neutral	0.117
NOTCH3	Q9UM47-1.2	V1629A	Neutral	0.4
NOTCH3	Q9UM47-1.2	V1629C	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	V1629D	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	V1629E	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	V1629F	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	V1629G	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	V1629H	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	V1629I	Neutral	0.008
NOTCH3	Q9UM47-1.2	V1629K	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	V1629L	Neutral	0.136
NOTCH3	Q9UM47-1.2	V1629M	Neutral	0.135
NOTCH3	Q9UM47-1.2	V1629N	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	V1629P	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	V1629Q	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	V1629R	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	V1629S	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	V1629T	Neutral	0.424
NOTCH3	Q9UM47-1.2	V1629W	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	V1629Y	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	R1630A	Neutral	0.032
NOTCH3	Q9UM47-1.2	R1630C	Neutral	0.429
NOTCH3	Q9UM47-1.2	R1630D	Neutral	0.142
NOTCH3	Q9UM47-1.2	R1630E	Neutral	0.009
NOTCH3	Q9UM47-1.2	R1630F	Neutral	0.478
NOTCH3	Q9UM47-1.2	R1630G	Neutral	0.124
NOTCH3	Q9UM47-1.2	R1630H	Neutral	0.009
NOTCH3	Q9UM47-1.2	R1630I	Neutral	0.467
NOTCH3	Q9UM47-1.2	R1630K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R1630L	Neutral	0.161
NOTCH3	Q9UM47-1.2	R1630M	Neutral	0.04
NOTCH3	Q9UM47-1.2	R1630N	Neutral	0.008
NOTCH3	Q9UM47-1.2	R1630P	Neutral	0.143
NOTCH3	Q9UM47-1.2	R1630Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	R1630S	Neutral	0.033
NOTCH3	Q9UM47-1.2	R1630T	Neutral	0.036
NOTCH3	Q9UM47-1.2	R1630V	Neutral	0.448
NOTCH3	Q9UM47-1.2	R1630W	Neutral	0.477
NOTCH3	Q9UM47-1.2	R1630Y	Neutral	0.169
NOTCH3	Q9UM47-1.2	G1631A	Neutral	0.006
NOTCH3	Q9UM47-1.2	G1631C	Neutral	0.346
NOTCH3	Q9UM47-1.2	G1631D	Neutral	0.024
NOTCH3	Q9UM47-1.2	G1631E	Neutral	0.096
NOTCH3	Q9UM47-1.2	G1631F	Neutral	0.306
NOTCH3	Q9UM47-1.2	G1631H	Neutral	0.092
NOTCH3	Q9UM47-1.2	G1631I	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	G1631K	Neutral	0.088
NOTCH3	Q9UM47-1.2	G1631L	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	G1631M	Neutral	0.314
NOTCH3	Q9UM47-1.2	G1631N	Neutral	0.005
NOTCH3	Q9UM47-1.2	G1631P	Neutral	0.102
NOTCH3	Q9UM47-1.2	G1631Q	Neutral	0.094
NOTCH3	Q9UM47-1.2	G1631R	Neutral	0.084
NOTCH3	Q9UM47-1.2	G1631S	Neutral	0.006
NOTCH3	Q9UM47-1.2	G1631T	Neutral	0.101
NOTCH3	Q9UM47-1.2	G1631V	Neutral	0.33
NOTCH3	Q9UM47-1.2	G1631W	Neutral	0.08
NOTCH3	Q9UM47-1.2	G1631Y	Neutral	0.299
NOTCH3	Q9UM47-1.2	E1632A	Neutral	0.38
NOTCH3	Q9UM47-1.2	E1632C	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	E1632D	Neutral	0.007
NOTCH3	Q9UM47-1.2	E1632F	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	E1632G	Pathogenic	0.722
NOTCH3	Q9UM47-1.2	E1632H	Neutral	0.133
NOTCH3	Q9UM47-1.2	E1632I	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	E1632K	Neutral	0.03
NOTCH3	Q9UM47-1.2	E1632L	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	E1632M	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	E1632N	Neutral	0.13
NOTCH3	Q9UM47-1.2	E1632P	Neutral	0.402
NOTCH3	Q9UM47-1.2	E1632Q	Neutral	0.007
NOTCH3	Q9UM47-1.2	E1632R	Neutral	0.12
NOTCH3	Q9UM47-1.2	E1632S	Neutral	0.121
NOTCH3	Q9UM47-1.2	E1632T	Neutral	0.404
NOTCH3	Q9UM47-1.2	E1632V	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	E1632W	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	E1632Y	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	P1633A	Neutral	0.021
NOTCH3	Q9UM47-1.2	P1633C	Neutral	0.327
NOTCH3	Q9UM47-1.2	P1633D	Neutral	0.023
NOTCH3	Q9UM47-1.2	P1633E	Neutral	0.022
NOTCH3	Q9UM47-1.2	P1633F	Pathogenic	0.655
NOTCH3	Q9UM47-1.2	P1633G	Neutral	0.085
NOTCH3	Q9UM47-1.2	P1633H	Neutral	0.089
NOTCH3	Q9UM47-1.2	P1633I	Neutral	0.303
NOTCH3	Q9UM47-1.2	P1633K	Neutral	0.02
NOTCH3	Q9UM47-1.2	P1633L	Neutral	0.303
NOTCH3	Q9UM47-1.2	P1633M	Neutral	0.087
NOTCH3	Q9UM47-1.2	P1633N	Neutral	0.096
NOTCH3	Q9UM47-1.2	P1633Q	Neutral	0.021
NOTCH3	Q9UM47-1.2	P1633R	Neutral	0.081
NOTCH3	Q9UM47-1.2	P1633S	Neutral	0.022
NOTCH3	Q9UM47-1.2	P1633T	Neutral	0.023
NOTCH3	Q9UM47-1.2	P1633V	Neutral	0.093
NOTCH3	Q9UM47-1.2	P1633W	Pathogenic	0.631
NOTCH3	Q9UM47-1.2	P1633Y	Neutral	0.288
NOTCH3	Q9UM47-1.2	L1634A	Neutral	0.041
NOTCH3	Q9UM47-1.2	L1634C	Neutral	0.044
NOTCH3	Q9UM47-1.2	L1634D	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	L1634E	Pathogenic	0.514
NOTCH3	Q9UM47-1.2	L1634F	Neutral	0.011
NOTCH3	Q9UM47-1.2	L1634G	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	L1634H	Pathogenic	0.521
NOTCH3	Q9UM47-1.2	L1634I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1634K	Neutral	0.192
NOTCH3	Q9UM47-1.2	L1634M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1634N	Pathogenic	0.502
NOTCH3	Q9UM47-1.2	L1634P	Neutral	0.493
NOTCH3	Q9UM47-1.2	L1634Q	Neutral	0.191
NOTCH3	Q9UM47-1.2	L1634R	Neutral	0.184
NOTCH3	Q9UM47-1.2	L1634S	Neutral	0.168
NOTCH3	Q9UM47-1.2	L1634T	Neutral	0.046
NOTCH3	Q9UM47-1.2	L1634V	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1634W	Neutral	0.173
NOTCH3	Q9UM47-1.2	L1634Y	Neutral	0.048
NOTCH3	Q9UM47-1.2	E1635A	Neutral	0.095
NOTCH3	Q9UM47-1.2	E1635C	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	E1635D	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1635F	Pathogenic	0.701
NOTCH3	Q9UM47-1.2	E1635G	Neutral	0.308
NOTCH3	Q9UM47-1.2	E1635H	Neutral	0.026
NOTCH3	Q9UM47-1.2	E1635I	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	E1635K	Neutral	0.005
NOTCH3	Q9UM47-1.2	E1635L	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	E1635M	Neutral	0.349
NOTCH3	Q9UM47-1.2	E1635N	Neutral	0.025
NOTCH3	Q9UM47-1.2	E1635P	Neutral	0.103
NOTCH3	Q9UM47-1.2	E1635Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1635R	Neutral	0.023
NOTCH3	Q9UM47-1.2	E1635S	Neutral	0.023
NOTCH3	Q9UM47-1.2	E1635T	Neutral	0.104
NOTCH3	Q9UM47-1.2	E1635V	Neutral	0.359
NOTCH3	Q9UM47-1.2	E1635W	Pathogenic	0.679
NOTCH3	Q9UM47-1.2	E1635Y	Neutral	0.334
NOTCH3	Q9UM47-1.2	P1636A	Neutral	0.237
NOTCH3	Q9UM47-1.2	P1636C	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	P1636D	Neutral	0.254
NOTCH3	Q9UM47-1.2	P1636E	Neutral	0.241
NOTCH3	Q9UM47-1.2	P1636F	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	P1636G	Pathogenic	0.568
NOTCH3	Q9UM47-1.2	P1636H	Pathogenic	0.581
NOTCH3	Q9UM47-1.2	P1636I	Pathogenic	0.861
NOTCH3	Q9UM47-1.2	P1636K	Neutral	0.224
NOTCH3	Q9UM47-1.2	P1636L	Pathogenic	0.861
NOTCH3	Q9UM47-1.2	P1636M	Pathogenic	0.576
NOTCH3	Q9UM47-1.2	P1636N	Pathogenic	0.603
NOTCH3	Q9UM47-1.2	P1636Q	Neutral	0.237
NOTCH3	Q9UM47-1.2	P1636R	Pathogenic	0.555
NOTCH3	Q9UM47-1.2	P1636S	Neutral	0.242
NOTCH3	Q9UM47-1.2	P1636T	Neutral	0.251
NOTCH3	Q9UM47-1.2	P1636V	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	P1636W	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	P1636Y	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	P1637A	Neutral	0.088
NOTCH3	Q9UM47-1.2	P1637C	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	P1637D	Neutral	0.096
NOTCH3	Q9UM47-1.2	P1637E	Neutral	0.09
NOTCH3	Q9UM47-1.2	P1637F	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	P1637G	Neutral	0.291
NOTCH3	Q9UM47-1.2	P1637H	Neutral	0.302
NOTCH3	Q9UM47-1.2	P1637I	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	P1637K	Neutral	0.082
NOTCH3	Q9UM47-1.2	P1637L	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	P1637M	Neutral	0.297
NOTCH3	Q9UM47-1.2	P1637N	Neutral	0.321
NOTCH3	Q9UM47-1.2	P1637Q	Neutral	0.088
NOTCH3	Q9UM47-1.2	P1637R	Neutral	0.28
NOTCH3	Q9UM47-1.2	P1637S	Neutral	0.09
NOTCH3	Q9UM47-1.2	P1637T	Neutral	0.094
NOTCH3	Q9UM47-1.2	P1637V	Neutral	0.312
NOTCH3	Q9UM47-1.2	P1637W	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	P1637Y	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	E1638A	Neutral	0.015
NOTCH3	Q9UM47-1.2	E1638C	Pathogenic	0.61
NOTCH3	Q9UM47-1.2	E1638D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1638F	Neutral	0.255
NOTCH3	Q9UM47-1.2	E1638G	Neutral	0.061
NOTCH3	Q9UM47-1.2	E1638H	Neutral	0.004
NOTCH3	Q9UM47-1.2	E1638I	Neutral	0.263
NOTCH3	Q9UM47-1.2	E1638K	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1638L	Neutral	0.263
NOTCH3	Q9UM47-1.2	E1638M	Neutral	0.072
NOTCH3	Q9UM47-1.2	E1638N	Neutral	0.004
NOTCH3	Q9UM47-1.2	E1638P	Neutral	0.017
NOTCH3	Q9UM47-1.2	E1638Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1638R	Neutral	0.003
NOTCH3	Q9UM47-1.2	E1638S	Neutral	0.003
NOTCH3	Q9UM47-1.2	E1638T	Neutral	0.017
NOTCH3	Q9UM47-1.2	E1638V	Neutral	0.075
NOTCH3	Q9UM47-1.2	E1638W	Neutral	0.235
NOTCH3	Q9UM47-1.2	E1638Y	Neutral	0.068
NOTCH3	Q9UM47-1.2	P1639A	Neutral	0.025
NOTCH3	Q9UM47-1.2	P1639C	Neutral	0.366
NOTCH3	Q9UM47-1.2	P1639D	Neutral	0.028
NOTCH3	Q9UM47-1.2	P1639E	Neutral	0.026
NOTCH3	Q9UM47-1.2	P1639F	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	P1639G	Neutral	0.099
NOTCH3	Q9UM47-1.2	P1639H	Neutral	0.104
NOTCH3	Q9UM47-1.2	P1639I	Neutral	0.341
NOTCH3	Q9UM47-1.2	P1639K	Neutral	0.023
NOTCH3	Q9UM47-1.2	P1639L	Neutral	0.341
NOTCH3	Q9UM47-1.2	P1639M	Neutral	0.102
NOTCH3	Q9UM47-1.2	P1639N	Neutral	0.113
NOTCH3	Q9UM47-1.2	P1639Q	Neutral	0.025
NOTCH3	Q9UM47-1.2	P1639R	Neutral	0.094
NOTCH3	Q9UM47-1.2	P1639S	Neutral	0.026
NOTCH3	Q9UM47-1.2	P1639T	Neutral	0.027
NOTCH3	Q9UM47-1.2	P1639V	Neutral	0.109
NOTCH3	Q9UM47-1.2	P1639W	Pathogenic	0.67
NOTCH3	Q9UM47-1.2	P1639Y	Neutral	0.325
NOTCH3	Q9UM47-1.2	S1640A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1640C	Neutral	0.016
NOTCH3	Q9UM47-1.2	S1640D	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1640E	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1640F	Neutral	0.058
NOTCH3	Q9UM47-1.2	S1640G	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1640H	Neutral	0.014
NOTCH3	Q9UM47-1.2	S1640I	Neutral	0.06
NOTCH3	Q9UM47-1.2	S1640K	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1640L	Neutral	0.06
NOTCH3	Q9UM47-1.2	S1640M	Neutral	0.014
NOTCH3	Q9UM47-1.2	S1640N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1640P	Neutral	0.016
NOTCH3	Q9UM47-1.2	S1640Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	S1640R	Neutral	0.013
NOTCH3	Q9UM47-1.2	S1640T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1640V	Neutral	0.064
NOTCH3	Q9UM47-1.2	S1640W	Neutral	0.202
NOTCH3	Q9UM47-1.2	S1640Y	Neutral	0.056
NOTCH3	Q9UM47-1.2	V1641A	Neutral	0.003
NOTCH3	Q9UM47-1.2	V1641C	Neutral	0.014
NOTCH3	Q9UM47-1.2	V1641D	Neutral	0.24
NOTCH3	Q9UM47-1.2	V1641E	Neutral	0.067
NOTCH3	Q9UM47-1.2	V1641F	Neutral	0.014
NOTCH3	Q9UM47-1.2	V1641G	Neutral	0.21
NOTCH3	Q9UM47-1.2	V1641H	Neutral	0.239
NOTCH3	Q9UM47-1.2	V1641I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V1641K	Neutral	0.061
NOTCH3	Q9UM47-1.2	V1641L	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1641M	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1641N	Neutral	0.243
NOTCH3	Q9UM47-1.2	V1641P	Neutral	0.064
NOTCH3	Q9UM47-1.2	V1641Q	Neutral	0.066
NOTCH3	Q9UM47-1.2	V1641R	Neutral	0.22
NOTCH3	Q9UM47-1.2	V1641S	Neutral	0.06
NOTCH3	Q9UM47-1.2	V1641T	Neutral	0.003
NOTCH3	Q9UM47-1.2	V1641W	Neutral	0.209
NOTCH3	Q9UM47-1.2	V1641Y	Neutral	0.014
NOTCH3	Q9UM47-1.2	P1642A	Neutral	0.039
NOTCH3	Q9UM47-1.2	P1642C	Neutral	0.473
NOTCH3	Q9UM47-1.2	P1642D	Neutral	0.042
NOTCH3	Q9UM47-1.2	P1642E	Neutral	0.04
NOTCH3	Q9UM47-1.2	P1642F	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	P1642G	Neutral	0.146
NOTCH3	Q9UM47-1.2	P1642H	Neutral	0.153
NOTCH3	Q9UM47-1.2	P1642I	Neutral	0.446
NOTCH3	Q9UM47-1.2	P1642K	Neutral	0.036
NOTCH3	Q9UM47-1.2	P1642L	Neutral	0.446
NOTCH3	Q9UM47-1.2	P1642M	Neutral	0.15
NOTCH3	Q9UM47-1.2	P1642N	Neutral	0.165
NOTCH3	Q9UM47-1.2	P1642Q	Neutral	0.039
NOTCH3	Q9UM47-1.2	P1642R	Neutral	0.139
NOTCH3	Q9UM47-1.2	P1642S	Neutral	0.04
NOTCH3	Q9UM47-1.2	P1642T	Neutral	0.042
NOTCH3	Q9UM47-1.2	P1642V	Neutral	0.159
NOTCH3	Q9UM47-1.2	P1642W	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	P1642Y	Neutral	0.428
NOTCH3	Q9UM47-1.2	L1643A	Neutral	0.292
NOTCH3	Q9UM47-1.2	L1643C	Neutral	0.306
NOTCH3	Q9UM47-1.2	L1643D	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	L1643E	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	L1643F	Neutral	0.096
NOTCH3	Q9UM47-1.2	L1643G	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	L1643H	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	L1643I	Neutral	0.005
NOTCH3	Q9UM47-1.2	L1643K	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	L1643M	Neutral	0.005
NOTCH3	Q9UM47-1.2	L1643N	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	L1643P	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	L1643Q	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	L1643R	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	L1643S	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	L1643T	Neutral	0.313
NOTCH3	Q9UM47-1.2	L1643V	Neutral	0.022
NOTCH3	Q9UM47-1.2	L1643W	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	L1643Y	Neutral	0.323
NOTCH3	Q9UM47-1.2	L1644A	Neutral	0.256
NOTCH3	Q9UM47-1.2	L1644C	Neutral	0.269
NOTCH3	Q9UM47-1.2	L1644D	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	L1644E	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	L1644F	Neutral	0.082
NOTCH3	Q9UM47-1.2	L1644G	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	L1644H	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	L1644I	Neutral	0.004
NOTCH3	Q9UM47-1.2	L1644K	Pathogenic	0.654
NOTCH3	Q9UM47-1.2	L1644M	Neutral	0.004
NOTCH3	Q9UM47-1.2	L1644N	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	L1644P	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	L1644Q	Pathogenic	0.654
NOTCH3	Q9UM47-1.2	L1644R	Pathogenic	0.643
NOTCH3	Q9UM47-1.2	L1644S	Pathogenic	0.617
NOTCH3	Q9UM47-1.2	L1644T	Neutral	0.276
NOTCH3	Q9UM47-1.2	L1644V	Neutral	0.019
NOTCH3	Q9UM47-1.2	L1644W	Pathogenic	0.625
NOTCH3	Q9UM47-1.2	L1644Y	Neutral	0.286
NOTCH3	Q9UM47-1.2	P1645A	Neutral	0.172
NOTCH3	Q9UM47-1.2	P1645C	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	P1645D	Neutral	0.186
NOTCH3	Q9UM47-1.2	P1645E	Neutral	0.175
NOTCH3	Q9UM47-1.2	P1645F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	P1645G	Neutral	0.468
NOTCH3	Q9UM47-1.2	P1645H	Neutral	0.481
NOTCH3	Q9UM47-1.2	P1645I	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	P1645K	Neutral	0.161
NOTCH3	Q9UM47-1.2	P1645L	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	P1645M	Neutral	0.475
NOTCH3	Q9UM47-1.2	P1645N	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	P1645Q	Neutral	0.172
NOTCH3	Q9UM47-1.2	P1645R	Neutral	0.455
NOTCH3	Q9UM47-1.2	P1645S	Neutral	0.176
NOTCH3	Q9UM47-1.2	P1645T	Neutral	0.183
NOTCH3	Q9UM47-1.2	P1645V	Neutral	0.494
NOTCH3	Q9UM47-1.2	P1645W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	P1645Y	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	L1646A	Neutral	0.332
NOTCH3	Q9UM47-1.2	L1646C	Neutral	0.347
NOTCH3	Q9UM47-1.2	L1646D	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L1646E	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	L1646F	Neutral	0.114
NOTCH3	Q9UM47-1.2	L1646G	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	L1646H	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	L1646I	Neutral	0.006
NOTCH3	Q9UM47-1.2	L1646K	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	L1646M	Neutral	0.006
NOTCH3	Q9UM47-1.2	L1646N	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	L1646P	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	L1646Q	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	L1646R	Pathogenic	0.722
NOTCH3	Q9UM47-1.2	L1646S	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	L1646T	Neutral	0.355
NOTCH3	Q9UM47-1.2	L1646V	Neutral	0.027
NOTCH3	Q9UM47-1.2	L1646W	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	L1646Y	Neutral	0.366
NOTCH3	Q9UM47-1.2	L1647A	Neutral	0.405
NOTCH3	Q9UM47-1.2	L1647C	Neutral	0.421
NOTCH3	Q9UM47-1.2	L1647D	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	L1647E	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	L1647F	Neutral	0.15
NOTCH3	Q9UM47-1.2	L1647G	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	L1647H	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	L1647I	Neutral	0.009
NOTCH3	Q9UM47-1.2	L1647K	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	L1647M	Neutral	0.009
NOTCH3	Q9UM47-1.2	L1647N	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	L1647P	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	L1647Q	Pathogenic	0.788
NOTCH3	Q9UM47-1.2	L1647R	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	L1647S	Pathogenic	0.761
NOTCH3	Q9UM47-1.2	L1647T	Neutral	0.429
NOTCH3	Q9UM47-1.2	L1647V	Neutral	0.036
NOTCH3	Q9UM47-1.2	L1647W	Pathogenic	0.767
NOTCH3	Q9UM47-1.2	L1647Y	Neutral	0.441
NOTCH3	Q9UM47-1.2	V1648A	Neutral	0.068
NOTCH3	Q9UM47-1.2	V1648C	Neutral	0.263
NOTCH3	Q9UM47-1.2	V1648D	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	V1648E	Pathogenic	0.636
NOTCH3	Q9UM47-1.2	V1648F	Neutral	0.256
NOTCH3	Q9UM47-1.2	V1648G	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	V1648H	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	V1648I	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1648K	Pathogenic	0.613
NOTCH3	Q9UM47-1.2	V1648L	Neutral	0.017
NOTCH3	Q9UM47-1.2	V1648M	Neutral	0.017
NOTCH3	Q9UM47-1.2	V1648N	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	V1648P	Pathogenic	0.624
NOTCH3	Q9UM47-1.2	V1648Q	Pathogenic	0.631
NOTCH3	Q9UM47-1.2	V1648R	Pathogenic	0.873
NOTCH3	Q9UM47-1.2	V1648S	Pathogenic	0.609
NOTCH3	Q9UM47-1.2	V1648T	Neutral	0.075
NOTCH3	Q9UM47-1.2	V1648W	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	V1648Y	Neutral	0.251
NOTCH3	Q9UM47-1.2	A1649C	Neutral	0.028
NOTCH3	Q9UM47-1.2	A1649D	Neutral	0.367
NOTCH3	Q9UM47-1.2	A1649E	Neutral	0.106
NOTCH3	Q9UM47-1.2	A1649F	Neutral	0.329
NOTCH3	Q9UM47-1.2	A1649G	Neutral	0.028
NOTCH3	Q9UM47-1.2	A1649H	Neutral	0.342
NOTCH3	Q9UM47-1.2	A1649I	Neutral	0.101
NOTCH3	Q9UM47-1.2	A1649K	Neutral	0.097
NOTCH3	Q9UM47-1.2	A1649L	Neutral	0.101
NOTCH3	Q9UM47-1.2	A1649M	Neutral	0.101
NOTCH3	Q9UM47-1.2	A1649N	Neutral	0.362
NOTCH3	Q9UM47-1.2	A1649P	Neutral	0.113
NOTCH3	Q9UM47-1.2	A1649Q	Neutral	0.104
NOTCH3	Q9UM47-1.2	A1649R	Neutral	0.093
NOTCH3	Q9UM47-1.2	A1649S	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1649T	Neutral	0.027
NOTCH3	Q9UM47-1.2	A1649V	Neutral	0.026
NOTCH3	Q9UM47-1.2	A1649W	Pathogenic	0.668
NOTCH3	Q9UM47-1.2	A1649Y	Neutral	0.323
NOTCH3	Q9UM47-1.2	G1650A	Neutral	0.009
NOTCH3	Q9UM47-1.2	G1650C	Neutral	0.44
NOTCH3	Q9UM47-1.2	G1650D	Neutral	0.036
NOTCH3	Q9UM47-1.2	G1650E	Neutral	0.136
NOTCH3	Q9UM47-1.2	G1650F	Neutral	0.396
NOTCH3	Q9UM47-1.2	G1650H	Neutral	0.132
NOTCH3	Q9UM47-1.2	G1650I	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	G1650K	Neutral	0.125
NOTCH3	Q9UM47-1.2	G1650L	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	G1650M	Neutral	0.405
NOTCH3	Q9UM47-1.2	G1650N	Neutral	0.008
NOTCH3	Q9UM47-1.2	G1650P	Neutral	0.145
NOTCH3	Q9UM47-1.2	G1650Q	Neutral	0.133
NOTCH3	Q9UM47-1.2	G1650R	Neutral	0.12
NOTCH3	Q9UM47-1.2	G1650S	Neutral	0.009
NOTCH3	Q9UM47-1.2	G1650T	Neutral	0.143
NOTCH3	Q9UM47-1.2	G1650V	Neutral	0.423
NOTCH3	Q9UM47-1.2	G1650W	Neutral	0.115
NOTCH3	Q9UM47-1.2	G1650Y	Neutral	0.389
NOTCH3	Q9UM47-1.2	A1651C	Neutral	0.118
NOTCH3	Q9UM47-1.2	A1651D	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	A1651E	Neutral	0.359
NOTCH3	Q9UM47-1.2	A1651F	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	A1651G	Neutral	0.118
NOTCH3	Q9UM47-1.2	A1651H	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	A1651I	Neutral	0.347
NOTCH3	Q9UM47-1.2	A1651K	Neutral	0.337
NOTCH3	Q9UM47-1.2	A1651L	Neutral	0.347
NOTCH3	Q9UM47-1.2	A1651M	Neutral	0.346
NOTCH3	Q9UM47-1.2	A1651N	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	A1651P	Neutral	0.375
NOTCH3	Q9UM47-1.2	A1651Q	Neutral	0.354
NOTCH3	Q9UM47-1.2	A1651R	Neutral	0.326
NOTCH3	Q9UM47-1.2	A1651S	Neutral	0.03
NOTCH3	Q9UM47-1.2	A1651T	Neutral	0.115
NOTCH3	Q9UM47-1.2	A1651V	Neutral	0.111
NOTCH3	Q9UM47-1.2	A1651W	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	A1651Y	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	V1652A	Neutral	0.129
NOTCH3	Q9UM47-1.2	V1652C	Neutral	0.419
NOTCH3	Q9UM47-1.2	V1652D	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	V1652E	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	V1652F	Neutral	0.41
NOTCH3	Q9UM47-1.2	V1652G	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	V1652H	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	V1652I	Neutral	0.002
NOTCH3	Q9UM47-1.2	V1652K	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	V1652L	Neutral	0.034
NOTCH3	Q9UM47-1.2	V1652M	Neutral	0.034
NOTCH3	Q9UM47-1.2	V1652N	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	V1652P	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	V1652Q	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	V1652R	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	V1652S	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	V1652T	Neutral	0.141
NOTCH3	Q9UM47-1.2	V1652W	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	V1652Y	Neutral	0.404
NOTCH3	Q9UM47-1.2	L1653A	Neutral	0.008
NOTCH3	Q9UM47-1.2	L1653C	Neutral	0.008
NOTCH3	Q9UM47-1.2	L1653D	Neutral	0.453
NOTCH3	Q9UM47-1.2	L1653E	Neutral	0.163
NOTCH3	Q9UM47-1.2	L1653F	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1653G	Neutral	0.411
NOTCH3	Q9UM47-1.2	L1653H	Neutral	0.167
NOTCH3	Q9UM47-1.2	L1653I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1653K	Neutral	0.042
NOTCH3	Q9UM47-1.2	L1653M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1653N	Neutral	0.157
NOTCH3	Q9UM47-1.2	L1653P	Neutral	0.152
NOTCH3	Q9UM47-1.2	L1653Q	Neutral	0.042
NOTCH3	Q9UM47-1.2	L1653R	Neutral	0.04
NOTCH3	Q9UM47-1.2	L1653S	Neutral	0.036
NOTCH3	Q9UM47-1.2	L1653T	Neutral	0.009
NOTCH3	Q9UM47-1.2	L1653V	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1653W	Neutral	0.037
NOTCH3	Q9UM47-1.2	L1653Y	Neutral	0.009
NOTCH3	Q9UM47-1.2	L1654A	Neutral	0.351
NOTCH3	Q9UM47-1.2	L1654C	Neutral	0.366
NOTCH3	Q9UM47-1.2	L1654D	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1654E	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	L1654F	Neutral	0.123
NOTCH3	Q9UM47-1.2	L1654G	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	L1654H	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	L1654I	Neutral	0.007
NOTCH3	Q9UM47-1.2	L1654K	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	L1654M	Neutral	0.007
NOTCH3	Q9UM47-1.2	L1654N	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	L1654P	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	L1654Q	Pathogenic	0.747
NOTCH3	Q9UM47-1.2	L1654R	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	L1654S	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	L1654T	Neutral	0.374
NOTCH3	Q9UM47-1.2	L1654V	Neutral	0.029
NOTCH3	Q9UM47-1.2	L1654W	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	L1654Y	Neutral	0.385
NOTCH3	Q9UM47-1.2	L1655A	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	L1655C	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	L1655D	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	L1655E	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	L1655F	Neutral	0.499
NOTCH3	Q9UM47-1.2	L1655G	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	L1655H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	L1655I	Neutral	0.048
NOTCH3	Q9UM47-1.2	L1655K	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	L1655M	Neutral	0.048
NOTCH3	Q9UM47-1.2	L1655N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	L1655P	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	L1655Q	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	L1655R	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	L1655S	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	L1655T	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	L1655V	Neutral	0.175
NOTCH3	Q9UM47-1.2	L1655W	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	L1655Y	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	V1656A	Neutral	0.038
NOTCH3	Q9UM47-1.2	V1656C	Neutral	0.16
NOTCH3	Q9UM47-1.2	V1656D	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	V1656E	Neutral	0.483
NOTCH3	Q9UM47-1.2	V1656F	Neutral	0.155
NOTCH3	Q9UM47-1.2	V1656G	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	V1656H	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	V1656I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V1656K	Neutral	0.459
NOTCH3	Q9UM47-1.2	V1656L	Neutral	0.009
NOTCH3	Q9UM47-1.2	V1656M	Neutral	0.009
NOTCH3	Q9UM47-1.2	V1656N	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	V1656P	Neutral	0.47
NOTCH3	Q9UM47-1.2	V1656Q	Neutral	0.477
NOTCH3	Q9UM47-1.2	V1656R	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	V1656S	Neutral	0.455
NOTCH3	Q9UM47-1.2	V1656T	Neutral	0.042
NOTCH3	Q9UM47-1.2	V1656W	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	V1656Y	Neutral	0.152
NOTCH3	Q9UM47-1.2	I1657A	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	I1657C	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	I1657D	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	I1657E	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	I1657F	Neutral	0.418
NOTCH3	Q9UM47-1.2	I1657G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1657H	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	I1657K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	I1657L	Neutral	0.035
NOTCH3	Q9UM47-1.2	I1657M	Neutral	0.142
NOTCH3	Q9UM47-1.2	I1657N	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	I1657P	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	I1657Q	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	I1657R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	I1657S	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	I1657T	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	I1657V	Neutral	0.007
NOTCH3	Q9UM47-1.2	I1657W	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	I1657Y	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	L1658A	Neutral	0.241
NOTCH3	Q9UM47-1.2	L1658C	Neutral	0.254
NOTCH3	Q9UM47-1.2	L1658D	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	L1658E	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	L1658F	Neutral	0.076
NOTCH3	Q9UM47-1.2	L1658G	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	L1658H	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	L1658I	Neutral	0.004
NOTCH3	Q9UM47-1.2	L1658K	Pathogenic	0.636
NOTCH3	Q9UM47-1.2	L1658M	Neutral	0.004
NOTCH3	Q9UM47-1.2	L1658N	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	L1658P	Pathogenic	0.878
NOTCH3	Q9UM47-1.2	L1658Q	Pathogenic	0.635
NOTCH3	Q9UM47-1.2	L1658R	Pathogenic	0.624
NOTCH3	Q9UM47-1.2	L1658S	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	L1658T	Neutral	0.26
NOTCH3	Q9UM47-1.2	L1658V	Neutral	0.017
NOTCH3	Q9UM47-1.2	L1658W	Pathogenic	0.606
NOTCH3	Q9UM47-1.2	L1658Y	Neutral	0.269
NOTCH3	Q9UM47-1.2	V1659A	Neutral	0.047
NOTCH3	Q9UM47-1.2	V1659C	Neutral	0.193
NOTCH3	Q9UM47-1.2	V1659D	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	V1659E	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	V1659F	Neutral	0.187
NOTCH3	Q9UM47-1.2	V1659G	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	V1659H	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	V1659I	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1659K	Pathogenic	0.515
NOTCH3	Q9UM47-1.2	V1659L	Neutral	0.011
NOTCH3	Q9UM47-1.2	V1659M	Neutral	0.011
NOTCH3	Q9UM47-1.2	V1659N	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	V1659P	Pathogenic	0.526
NOTCH3	Q9UM47-1.2	V1659Q	Pathogenic	0.534
NOTCH3	Q9UM47-1.2	V1659R	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	V1659S	Pathogenic	0.512
NOTCH3	Q9UM47-1.2	V1659T	Neutral	0.052
NOTCH3	Q9UM47-1.2	V1659W	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	V1659Y	Neutral	0.183
NOTCH3	Q9UM47-1.2	L1660A	Neutral	0.439
NOTCH3	Q9UM47-1.2	L1660C	Neutral	0.455
NOTCH3	Q9UM47-1.2	L1660D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	L1660E	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	L1660F	Neutral	0.169
NOTCH3	Q9UM47-1.2	L1660G	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	L1660H	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	L1660I	Neutral	0.01
NOTCH3	Q9UM47-1.2	L1660K	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	L1660M	Neutral	0.01
NOTCH3	Q9UM47-1.2	L1660N	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	L1660P	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	L1660Q	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	L1660R	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	L1660S	Pathogenic	0.785
NOTCH3	Q9UM47-1.2	L1660T	Neutral	0.463
NOTCH3	Q9UM47-1.2	L1660V	Neutral	0.042
NOTCH3	Q9UM47-1.2	L1660W	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	L1660Y	Neutral	0.475
NOTCH3	Q9UM47-1.2	G1661A	Neutral	0.417
NOTCH3	Q9UM47-1.2	G1661C	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	G1661D	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	G1661E	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	G1661F	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	G1661H	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	G1661I	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	G1661K	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	G1661L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	G1661M	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	G1661N	Neutral	0.391
NOTCH3	Q9UM47-1.2	G1661P	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	G1661Q	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	G1661R	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	G1661S	Neutral	0.411
NOTCH3	Q9UM47-1.2	G1661T	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	G1661V	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	G1661W	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	G1661Y	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	V1662A	Pathogenic	0.608
NOTCH3	Q9UM47-1.2	V1662C	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	V1662D	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	V1662E	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	V1662F	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	V1662G	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	V1662H	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	V1662I	Neutral	0.017
NOTCH3	Q9UM47-1.2	V1662K	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	V1662L	Neutral	0.268
NOTCH3	Q9UM47-1.2	V1662M	Neutral	0.267
NOTCH3	Q9UM47-1.2	V1662N	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	V1662P	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	V1662Q	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	V1662R	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	V1662S	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	V1662T	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	V1662W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	V1662Y	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	M1663A	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	M1663C	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	M1663D	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	M1663E	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	M1663F	Neutral	0.336
NOTCH3	Q9UM47-1.2	M1663G	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	M1663H	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	M1663I	Neutral	0.104
NOTCH3	Q9UM47-1.2	M1663K	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	M1663L	Neutral	0.025
NOTCH3	Q9UM47-1.2	M1663N	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	M1663P	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	M1663Q	Neutral	0.338
NOTCH3	Q9UM47-1.2	M1663R	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	M1663S	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	M1663T	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	M1663V	Neutral	0.097
NOTCH3	Q9UM47-1.2	M1663W	Pathogenic	0.675
NOTCH3	Q9UM47-1.2	M1663Y	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	V1664A	Neutral	0.114
NOTCH3	Q9UM47-1.2	V1664C	Neutral	0.385
NOTCH3	Q9UM47-1.2	V1664D	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	V1664E	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	V1664F	Neutral	0.376
NOTCH3	Q9UM47-1.2	V1664G	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	V1664H	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	V1664I	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1664K	Pathogenic	0.736
NOTCH3	Q9UM47-1.2	V1664L	Neutral	0.029
NOTCH3	Q9UM47-1.2	V1664M	Neutral	0.029
NOTCH3	Q9UM47-1.2	V1664N	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	V1664P	Pathogenic	0.744
NOTCH3	Q9UM47-1.2	V1664Q	Pathogenic	0.75
NOTCH3	Q9UM47-1.2	V1664R	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	V1664S	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	V1664T	Neutral	0.125
NOTCH3	Q9UM47-1.2	V1664W	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	V1664Y	Neutral	0.37
NOTCH3	Q9UM47-1.2	A1665C	Neutral	0.067
NOTCH3	Q9UM47-1.2	A1665D	Pathogenic	0.594
NOTCH3	Q9UM47-1.2	A1665E	Neutral	0.23
NOTCH3	Q9UM47-1.2	A1665F	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	A1665G	Neutral	0.067
NOTCH3	Q9UM47-1.2	A1665H	Pathogenic	0.566
NOTCH3	Q9UM47-1.2	A1665I	Neutral	0.221
NOTCH3	Q9UM47-1.2	A1665K	Neutral	0.213
NOTCH3	Q9UM47-1.2	A1665L	Neutral	0.221
NOTCH3	Q9UM47-1.2	A1665M	Neutral	0.22
NOTCH3	Q9UM47-1.2	A1665N	Pathogenic	0.589
NOTCH3	Q9UM47-1.2	A1665P	Neutral	0.243
NOTCH3	Q9UM47-1.2	A1665Q	Neutral	0.226
NOTCH3	Q9UM47-1.2	A1665R	Neutral	0.205
NOTCH3	Q9UM47-1.2	A1665S	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1665T	Neutral	0.065
NOTCH3	Q9UM47-1.2	A1665V	Neutral	0.063
NOTCH3	Q9UM47-1.2	A1665W	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	A1665Y	Pathogenic	0.546
NOTCH3	Q9UM47-1.2	R1666A	Neutral	0.366
NOTCH3	Q9UM47-1.2	R1666C	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	R1666D	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	R1666E	Neutral	0.129
NOTCH3	Q9UM47-1.2	R1666F	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	R1666G	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	R1666H	Neutral	0.133
NOTCH3	Q9UM47-1.2	R1666I	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	R1666K	Neutral	0.008
NOTCH3	Q9UM47-1.2	R1666L	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	R1666M	Neutral	0.42
NOTCH3	Q9UM47-1.2	R1666N	Neutral	0.123
NOTCH3	Q9UM47-1.2	R1666P	Pathogenic	0.742
NOTCH3	Q9UM47-1.2	R1666Q	Neutral	0.032
NOTCH3	Q9UM47-1.2	R1666S	Neutral	0.37
NOTCH3	Q9UM47-1.2	R1666T	Neutral	0.389
NOTCH3	Q9UM47-1.2	R1666V	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	R1666W	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	R1666Y	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	R1667A	Neutral	0.373
NOTCH3	Q9UM47-1.2	R1667C	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	R1667D	Pathogenic	0.747
NOTCH3	Q9UM47-1.2	R1667E	Neutral	0.132
NOTCH3	Q9UM47-1.2	R1667F	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	R1667G	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	R1667H	Neutral	0.137
NOTCH3	Q9UM47-1.2	R1667I	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	R1667K	Neutral	0.008
NOTCH3	Q9UM47-1.2	R1667L	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	R1667M	Neutral	0.428
NOTCH3	Q9UM47-1.2	R1667N	Neutral	0.127
NOTCH3	Q9UM47-1.2	R1667P	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	R1667Q	Neutral	0.033
NOTCH3	Q9UM47-1.2	R1667S	Neutral	0.378
NOTCH3	Q9UM47-1.2	R1667T	Neutral	0.397
NOTCH3	Q9UM47-1.2	R1667V	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	R1667W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	R1667Y	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	K1668A	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	K1668C	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	K1668D	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	K1668E	Neutral	0.098
NOTCH3	Q9UM47-1.2	K1668F	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	K1668G	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	K1668H	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	K1668I	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	K1668L	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	K1668M	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	K1668N	Neutral	0.319
NOTCH3	Q9UM47-1.2	K1668P	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	K1668Q	Neutral	0.1
NOTCH3	Q9UM47-1.2	K1668R	Neutral	0.024
NOTCH3	Q9UM47-1.2	K1668S	Neutral	0.301
NOTCH3	Q9UM47-1.2	K1668T	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	K1668V	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	K1668W	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	K1668Y	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	R1669A	Pathogenic	0.671
NOTCH3	Q9UM47-1.2	R1669C	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	R1669D	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	R1669E	Neutral	0.343
NOTCH3	Q9UM47-1.2	R1669F	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	R1669G	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	R1669H	Neutral	0.353
NOTCH3	Q9UM47-1.2	R1669I	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	R1669K	Neutral	0.027
NOTCH3	Q9UM47-1.2	R1669L	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	R1669M	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	R1669N	Neutral	0.332
NOTCH3	Q9UM47-1.2	R1669P	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	R1669Q	Neutral	0.105
NOTCH3	Q9UM47-1.2	R1669S	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	R1669T	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	R1669V	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	R1669W	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	R1669Y	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	E1670A	Neutral	0.178
NOTCH3	Q9UM47-1.2	E1670C	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	E1670D	Neutral	0.003
NOTCH3	Q9UM47-1.2	E1670F	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	E1670G	Neutral	0.478
NOTCH3	Q9UM47-1.2	E1670H	Neutral	0.051
NOTCH3	Q9UM47-1.2	E1670I	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	E1670K	Neutral	0.011
NOTCH3	Q9UM47-1.2	E1670L	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	E1670M	Pathogenic	0.525
NOTCH3	Q9UM47-1.2	E1670N	Neutral	0.05
NOTCH3	Q9UM47-1.2	E1670P	Neutral	0.192
NOTCH3	Q9UM47-1.2	E1670Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	E1670R	Neutral	0.046
NOTCH3	Q9UM47-1.2	E1670S	Neutral	0.046
NOTCH3	Q9UM47-1.2	E1670T	Neutral	0.193
NOTCH3	Q9UM47-1.2	E1670V	Pathogenic	0.535
NOTCH3	Q9UM47-1.2	E1670W	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	E1670Y	Pathogenic	0.508
NOTCH3	Q9UM47-1.2	H1671A	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	H1671C	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	H1671D	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	H1671E	Pathogenic	0.543
NOTCH3	Q9UM47-1.2	H1671F	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	H1671G	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	H1671I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	H1671K	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	H1671L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	H1671M	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	H1671N	Neutral	0.199
NOTCH3	Q9UM47-1.2	H1671P	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	H1671Q	Pathogenic	0.546
NOTCH3	Q9UM47-1.2	H1671R	Pathogenic	0.523
NOTCH3	Q9UM47-1.2	H1671S	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	H1671T	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	H1671V	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	H1671W	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	H1671Y	Neutral	0.051
NOTCH3	Q9UM47-1.2	S1672A	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1672C	Neutral	0.086
NOTCH3	Q9UM47-1.2	S1672D	Neutral	0.02
NOTCH3	Q9UM47-1.2	S1672E	Neutral	0.019
NOTCH3	Q9UM47-1.2	S1672F	Neutral	0.263
NOTCH3	Q9UM47-1.2	S1672G	Neutral	0.019
NOTCH3	Q9UM47-1.2	S1672H	Neutral	0.076
NOTCH3	Q9UM47-1.2	S1672I	Neutral	0.272
NOTCH3	Q9UM47-1.2	S1672K	Neutral	0.017
NOTCH3	Q9UM47-1.2	S1672L	Neutral	0.272
NOTCH3	Q9UM47-1.2	S1672M	Neutral	0.075
NOTCH3	Q9UM47-1.2	S1672N	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1672P	Neutral	0.085
NOTCH3	Q9UM47-1.2	S1672Q	Neutral	0.018
NOTCH3	Q9UM47-1.2	S1672R	Neutral	0.069
NOTCH3	Q9UM47-1.2	S1672T	Neutral	0.004
NOTCH3	Q9UM47-1.2	S1672V	Neutral	0.285
NOTCH3	Q9UM47-1.2	S1672W	Pathogenic	0.595
NOTCH3	Q9UM47-1.2	S1672Y	Neutral	0.258
NOTCH3	Q9UM47-1.2	T1673A	Neutral	0.008
NOTCH3	Q9UM47-1.2	T1673C	Neutral	0.037
NOTCH3	Q9UM47-1.2	T1673D	Neutral	0.038
NOTCH3	Q9UM47-1.2	T1673E	Neutral	0.036
NOTCH3	Q9UM47-1.2	T1673F	Neutral	0.133
NOTCH3	Q9UM47-1.2	T1673G	Neutral	0.131
NOTCH3	Q9UM47-1.2	T1673H	Neutral	0.139
NOTCH3	Q9UM47-1.2	T1673I	Neutral	0.034
NOTCH3	Q9UM47-1.2	T1673K	Neutral	0.033
NOTCH3	Q9UM47-1.2	T1673L	Neutral	0.034
NOTCH3	Q9UM47-1.2	T1673M	Neutral	0.034
NOTCH3	Q9UM47-1.2	T1673N	Neutral	0.008
NOTCH3	Q9UM47-1.2	T1673P	Neutral	0.037
NOTCH3	Q9UM47-1.2	T1673Q	Neutral	0.035
NOTCH3	Q9UM47-1.2	T1673R	Neutral	0.031
NOTCH3	Q9UM47-1.2	T1673S	Neutral	0.002
NOTCH3	Q9UM47-1.2	T1673V	Neutral	0.008
NOTCH3	Q9UM47-1.2	T1673W	Neutral	0.121
NOTCH3	Q9UM47-1.2	T1673Y	Neutral	0.13
NOTCH3	Q9UM47-1.2	L1674A	Pathogenic	0.566
NOTCH3	Q9UM47-1.2	L1674C	Pathogenic	0.582
NOTCH3	Q9UM47-1.2	L1674D	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	L1674E	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	L1674F	Neutral	0.253
NOTCH3	Q9UM47-1.2	L1674G	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	L1674H	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	L1674I	Neutral	0.017
NOTCH3	Q9UM47-1.2	L1674K	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	L1674M	Neutral	0.017
NOTCH3	Q9UM47-1.2	L1674N	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	L1674P	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	L1674Q	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	L1674R	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	L1674S	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	L1674T	Pathogenic	0.59
NOTCH3	Q9UM47-1.2	L1674V	Neutral	0.067
NOTCH3	Q9UM47-1.2	L1674W	Pathogenic	0.863
NOTCH3	Q9UM47-1.2	L1674Y	Pathogenic	0.602
NOTCH3	Q9UM47-1.2	W1675A	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1675C	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1675D	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1675E	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1675F	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	W1675G	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1675H	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1675I	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1675K	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1675L	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1675M	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	W1675N	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1675P	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1675Q	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1675R	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1675S	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1675T	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1675V	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1675Y	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	F1676A	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	F1676C	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	F1676D	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	F1676E	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	F1676G	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	F1676H	Pathogenic	0.756
NOTCH3	Q9UM47-1.2	F1676I	Neutral	0.407
NOTCH3	Q9UM47-1.2	F1676K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	F1676L	Neutral	0.407
NOTCH3	Q9UM47-1.2	F1676M	Neutral	0.408
NOTCH3	Q9UM47-1.2	F1676N	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	F1676P	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F1676Q	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	F1676R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	F1676S	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	F1676T	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	F1676V	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	F1676W	Neutral	0.124
NOTCH3	Q9UM47-1.2	F1676Y	Neutral	0.007
NOTCH3	Q9UM47-1.2	P1677A	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	P1677C	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	P1677D	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	P1677E	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	P1677F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P1677G	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	P1677H	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	P1677I	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	P1677K	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	P1677L	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	P1677M	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	P1677N	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	P1677Q	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	P1677R	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	P1677S	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	P1677T	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	P1677V	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	P1677W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P1677Y	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	E1678A	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	E1678C	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	E1678D	Neutral	0.025
NOTCH3	Q9UM47-1.2	E1678F	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	E1678G	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	E1678H	Neutral	0.36
NOTCH3	Q9UM47-1.2	E1678I	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	E1678K	Neutral	0.103
NOTCH3	Q9UM47-1.2	E1678L	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	E1678M	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	E1678N	Neutral	0.355
NOTCH3	Q9UM47-1.2	E1678P	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	E1678Q	Neutral	0.027
NOTCH3	Q9UM47-1.2	E1678R	Neutral	0.333
NOTCH3	Q9UM47-1.2	E1678S	Neutral	0.336
NOTCH3	Q9UM47-1.2	E1678T	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	E1678V	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	E1678W	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	E1678Y	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	G1679A	Neutral	0.22
NOTCH3	Q9UM47-1.2	G1679C	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G1679D	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	G1679E	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	G1679F	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G1679H	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	G1679I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1679K	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	G1679L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1679M	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G1679N	Neutral	0.202
NOTCH3	Q9UM47-1.2	G1679P	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	G1679Q	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	G1679R	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	G1679S	Neutral	0.215
NOTCH3	Q9UM47-1.2	G1679T	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	G1679V	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1679W	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	G1679Y	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	F1680A	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	F1680C	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	F1680D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F1680E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1680G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F1680H	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	F1680I	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	F1680K	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1680L	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	F1680M	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	F1680N	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F1680P	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	F1680Q	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1680R	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1680S	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	F1680T	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	F1680V	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	F1680W	Neutral	0.402
NOTCH3	Q9UM47-1.2	F1680Y	Neutral	0.034
NOTCH3	Q9UM47-1.2	S1681A	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1681C	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1681D	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1681E	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1681F	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1681G	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1681H	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1681I	Neutral	0.007
NOTCH3	Q9UM47-1.2	S1681K	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1681L	Neutral	0.007
NOTCH3	Q9UM47-1.2	S1681M	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1681N	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1681P	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1681Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1681R	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1681T	Neutral	0.0
NOTCH3	Q9UM47-1.2	S1681V	Neutral	0.007
NOTCH3	Q9UM47-1.2	S1681W	Neutral	0.026
NOTCH3	Q9UM47-1.2	S1681Y	Neutral	0.006
NOTCH3	Q9UM47-1.2	L1682A	Neutral	0.124
NOTCH3	Q9UM47-1.2	L1682C	Neutral	0.132
NOTCH3	Q9UM47-1.2	L1682D	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	L1682E	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	L1682F	Neutral	0.036
NOTCH3	Q9UM47-1.2	L1682G	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	L1682H	Pathogenic	0.782
NOTCH3	Q9UM47-1.2	L1682I	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1682K	Neutral	0.438
NOTCH3	Q9UM47-1.2	L1682M	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1682N	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	L1682P	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	L1682Q	Neutral	0.437
NOTCH3	Q9UM47-1.2	L1682R	Neutral	0.426
NOTCH3	Q9UM47-1.2	L1682S	Neutral	0.399
NOTCH3	Q9UM47-1.2	L1682T	Neutral	0.136
NOTCH3	Q9UM47-1.2	L1682V	Neutral	0.008
NOTCH3	Q9UM47-1.2	L1682W	Neutral	0.407
NOTCH3	Q9UM47-1.2	L1682Y	Neutral	0.141
NOTCH3	Q9UM47-1.2	H1683A	Neutral	0.166
NOTCH3	Q9UM47-1.2	H1683C	Neutral	0.495
NOTCH3	Q9UM47-1.2	H1683D	Neutral	0.046
NOTCH3	Q9UM47-1.2	H1683E	Neutral	0.011
NOTCH3	Q9UM47-1.2	H1683F	Neutral	0.048
NOTCH3	Q9UM47-1.2	H1683G	Neutral	0.156
NOTCH3	Q9UM47-1.2	H1683I	Pathogenic	0.522
NOTCH3	Q9UM47-1.2	H1683K	Neutral	0.048
NOTCH3	Q9UM47-1.2	H1683L	Pathogenic	0.521
NOTCH3	Q9UM47-1.2	H1683M	Neutral	0.193
NOTCH3	Q9UM47-1.2	H1683N	Neutral	0.002
NOTCH3	Q9UM47-1.2	H1683P	Neutral	0.179
NOTCH3	Q9UM47-1.2	H1683Q	Neutral	0.011
NOTCH3	Q9UM47-1.2	H1683R	Neutral	0.01
NOTCH3	Q9UM47-1.2	H1683S	Neutral	0.043
NOTCH3	Q9UM47-1.2	H1683T	Neutral	0.18
NOTCH3	Q9UM47-1.2	H1683V	Pathogenic	0.514
NOTCH3	Q9UM47-1.2	H1683W	Neutral	0.171
NOTCH3	Q9UM47-1.2	H1683Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	K1684A	Neutral	0.173
NOTCH3	Q9UM47-1.2	K1684C	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	K1684D	Neutral	0.186
NOTCH3	Q9UM47-1.2	K1684E	Neutral	0.012
NOTCH3	Q9UM47-1.2	K1684F	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	K1684G	Neutral	0.47
NOTCH3	Q9UM47-1.2	K1684H	Neutral	0.203
NOTCH3	Q9UM47-1.2	K1684I	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	K1684L	Pathogenic	0.546
NOTCH3	Q9UM47-1.2	K1684M	Neutral	0.208
NOTCH3	Q9UM47-1.2	K1684N	Neutral	0.049
NOTCH3	Q9UM47-1.2	K1684P	Neutral	0.187
NOTCH3	Q9UM47-1.2	K1684Q	Neutral	0.012
NOTCH3	Q9UM47-1.2	K1684R	Neutral	0.003
NOTCH3	Q9UM47-1.2	K1684S	Neutral	0.045
NOTCH3	Q9UM47-1.2	K1684T	Neutral	0.188
NOTCH3	Q9UM47-1.2	K1684V	Pathogenic	0.527
NOTCH3	Q9UM47-1.2	K1684W	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	K1684Y	Pathogenic	0.549
NOTCH3	Q9UM47-1.2	D1685A	Neutral	0.387
NOTCH3	Q9UM47-1.2	D1685C	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	D1685E	Neutral	0.001
NOTCH3	Q9UM47-1.2	D1685F	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	D1685G	Neutral	0.114
NOTCH3	Q9UM47-1.2	D1685H	Neutral	0.12
NOTCH3	Q9UM47-1.2	D1685I	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	D1685K	Neutral	0.113
NOTCH3	Q9UM47-1.2	D1685L	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	D1685M	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	D1685N	Neutral	0.007
NOTCH3	Q9UM47-1.2	D1685P	Neutral	0.132
NOTCH3	Q9UM47-1.2	D1685Q	Neutral	0.03
NOTCH3	Q9UM47-1.2	D1685R	Neutral	0.356
NOTCH3	Q9UM47-1.2	D1685S	Neutral	0.03
NOTCH3	Q9UM47-1.2	D1685T	Neutral	0.131
NOTCH3	Q9UM47-1.2	D1685V	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	D1685W	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	D1685Y	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	V1686A	Neutral	0.006
NOTCH3	Q9UM47-1.2	V1686C	Neutral	0.029
NOTCH3	Q9UM47-1.2	V1686D	Neutral	0.392
NOTCH3	Q9UM47-1.2	V1686E	Neutral	0.128
NOTCH3	Q9UM47-1.2	V1686F	Neutral	0.028
NOTCH3	Q9UM47-1.2	V1686G	Neutral	0.352
NOTCH3	Q9UM47-1.2	V1686H	Neutral	0.391
NOTCH3	Q9UM47-1.2	V1686I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V1686K	Neutral	0.118
NOTCH3	Q9UM47-1.2	V1686L	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1686M	Neutral	0.001
NOTCH3	Q9UM47-1.2	V1686N	Neutral	0.396
NOTCH3	Q9UM47-1.2	V1686P	Neutral	0.122
NOTCH3	Q9UM47-1.2	V1686Q	Neutral	0.126
NOTCH3	Q9UM47-1.2	V1686R	Neutral	0.366
NOTCH3	Q9UM47-1.2	V1686S	Neutral	0.116
NOTCH3	Q9UM47-1.2	V1686T	Neutral	0.007
NOTCH3	Q9UM47-1.2	V1686W	Neutral	0.35
NOTCH3	Q9UM47-1.2	V1686Y	Neutral	0.027
NOTCH3	Q9UM47-1.2	A1687C	Neutral	0.014
NOTCH3	Q9UM47-1.2	A1687D	Neutral	0.221
NOTCH3	Q9UM47-1.2	A1687E	Neutral	0.055
NOTCH3	Q9UM47-1.2	A1687F	Neutral	0.193
NOTCH3	Q9UM47-1.2	A1687G	Neutral	0.014
NOTCH3	Q9UM47-1.2	A1687H	Neutral	0.202
NOTCH3	Q9UM47-1.2	A1687I	Neutral	0.052
NOTCH3	Q9UM47-1.2	A1687K	Neutral	0.05
NOTCH3	Q9UM47-1.2	A1687L	Neutral	0.052
NOTCH3	Q9UM47-1.2	A1687M	Neutral	0.052
NOTCH3	Q9UM47-1.2	A1687N	Neutral	0.217
NOTCH3	Q9UM47-1.2	A1687P	Neutral	0.059
NOTCH3	Q9UM47-1.2	A1687Q	Neutral	0.054
NOTCH3	Q9UM47-1.2	A1687R	Neutral	0.048
NOTCH3	Q9UM47-1.2	A1687S	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1687T	Neutral	0.013
NOTCH3	Q9UM47-1.2	A1687V	Neutral	0.013
NOTCH3	Q9UM47-1.2	A1687W	Neutral	0.496
NOTCH3	Q9UM47-1.2	A1687Y	Neutral	0.189
NOTCH3	Q9UM47-1.2	S1688A	Neutral	0.014
NOTCH3	Q9UM47-1.2	S1688C	Neutral	0.228
NOTCH3	Q9UM47-1.2	S1688D	Neutral	0.06
NOTCH3	Q9UM47-1.2	S1688E	Neutral	0.056
NOTCH3	Q9UM47-1.2	S1688F	Pathogenic	0.529
NOTCH3	Q9UM47-1.2	S1688G	Neutral	0.058
NOTCH3	Q9UM47-1.2	S1688H	Neutral	0.206
NOTCH3	Q9UM47-1.2	S1688I	Pathogenic	0.539
NOTCH3	Q9UM47-1.2	S1688K	Neutral	0.051
NOTCH3	Q9UM47-1.2	S1688L	Pathogenic	0.539
NOTCH3	Q9UM47-1.2	S1688M	Neutral	0.204
NOTCH3	Q9UM47-1.2	S1688N	Neutral	0.013
NOTCH3	Q9UM47-1.2	S1688P	Neutral	0.225
NOTCH3	Q9UM47-1.2	S1688Q	Neutral	0.055
NOTCH3	Q9UM47-1.2	S1688R	Neutral	0.189
NOTCH3	Q9UM47-1.2	S1688T	Neutral	0.014
NOTCH3	Q9UM47-1.2	S1688V	Pathogenic	0.556
NOTCH3	Q9UM47-1.2	S1688W	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	S1688Y	Pathogenic	0.521
NOTCH3	Q9UM47-1.2	G1689A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1689C	Neutral	0.149
NOTCH3	Q9UM47-1.2	G1689D	Neutral	0.008
NOTCH3	Q9UM47-1.2	G1689E	Neutral	0.034
NOTCH3	Q9UM47-1.2	G1689F	Neutral	0.128
NOTCH3	Q9UM47-1.2	G1689H	Neutral	0.033
NOTCH3	Q9UM47-1.2	G1689I	Neutral	0.41
NOTCH3	Q9UM47-1.2	G1689K	Neutral	0.031
NOTCH3	Q9UM47-1.2	G1689L	Neutral	0.41
NOTCH3	Q9UM47-1.2	G1689M	Neutral	0.132
NOTCH3	Q9UM47-1.2	G1689N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1689P	Neutral	0.037
NOTCH3	Q9UM47-1.2	G1689Q	Neutral	0.033
NOTCH3	Q9UM47-1.2	G1689R	Neutral	0.029
NOTCH3	Q9UM47-1.2	G1689S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1689T	Neutral	0.036
NOTCH3	Q9UM47-1.2	G1689V	Neutral	0.14
NOTCH3	Q9UM47-1.2	G1689W	Neutral	0.028
NOTCH3	Q9UM47-1.2	G1689Y	Neutral	0.124
NOTCH3	Q9UM47-1.2	H1690A	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	H1690C	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	H1690D	Neutral	0.326
NOTCH3	Q9UM47-1.2	H1690E	Neutral	0.102
NOTCH3	Q9UM47-1.2	H1690F	Neutral	0.336
NOTCH3	Q9UM47-1.2	H1690G	Pathogenic	0.649
NOTCH3	Q9UM47-1.2	H1690I	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	H1690K	Neutral	0.335
NOTCH3	Q9UM47-1.2	H1690L	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	H1690M	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	H1690N	Neutral	0.023
NOTCH3	Q9UM47-1.2	H1690P	Pathogenic	0.686
NOTCH3	Q9UM47-1.2	H1690Q	Neutral	0.103
NOTCH3	Q9UM47-1.2	H1690R	Neutral	0.095
NOTCH3	Q9UM47-1.2	H1690S	Neutral	0.309
NOTCH3	Q9UM47-1.2	H1690T	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	H1690V	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	H1690W	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	H1690Y	Neutral	0.005
NOTCH3	Q9UM47-1.2	K1691A	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	K1691C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	K1691D	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	K1691E	Neutral	0.152
NOTCH3	Q9UM47-1.2	K1691F	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	K1691G	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	K1691H	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	K1691I	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	K1691L	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	K1691M	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	K1691N	Neutral	0.436
NOTCH3	Q9UM47-1.2	K1691P	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	K1691Q	Neutral	0.155
NOTCH3	Q9UM47-1.2	K1691R	Neutral	0.04
NOTCH3	Q9UM47-1.2	K1691S	Neutral	0.416
NOTCH3	Q9UM47-1.2	K1691T	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	K1691V	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	K1691W	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	K1691Y	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	G1692A	Neutral	0.004
NOTCH3	Q9UM47-1.2	G1692C	Neutral	0.279
NOTCH3	Q9UM47-1.2	G1692D	Neutral	0.018
NOTCH3	Q9UM47-1.2	G1692E	Neutral	0.072
NOTCH3	Q9UM47-1.2	G1692F	Neutral	0.244
NOTCH3	Q9UM47-1.2	G1692H	Neutral	0.07
NOTCH3	Q9UM47-1.2	G1692I	Pathogenic	0.605
NOTCH3	Q9UM47-1.2	G1692K	Neutral	0.066
NOTCH3	Q9UM47-1.2	G1692L	Pathogenic	0.605
NOTCH3	Q9UM47-1.2	G1692M	Neutral	0.251
NOTCH3	Q9UM47-1.2	G1692N	Neutral	0.004
NOTCH3	Q9UM47-1.2	G1692P	Neutral	0.077
NOTCH3	Q9UM47-1.2	G1692Q	Neutral	0.071
NOTCH3	Q9UM47-1.2	G1692R	Neutral	0.063
NOTCH3	Q9UM47-1.2	G1692S	Neutral	0.004
NOTCH3	Q9UM47-1.2	G1692T	Neutral	0.076
NOTCH3	Q9UM47-1.2	G1692V	Neutral	0.265
NOTCH3	Q9UM47-1.2	G1692W	Neutral	0.06
NOTCH3	Q9UM47-1.2	G1692Y	Neutral	0.239
NOTCH3	Q9UM47-1.2	R1693A	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	R1693C	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	R1693D	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	R1693E	Pathogenic	0.541
NOTCH3	Q9UM47-1.2	R1693F	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1693G	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	R1693H	Pathogenic	0.551
NOTCH3	Q9UM47-1.2	R1693I	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1693K	Neutral	0.059
NOTCH3	Q9UM47-1.2	R1693L	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	R1693M	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	R1693N	Pathogenic	0.528
NOTCH3	Q9UM47-1.2	R1693P	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	R1693Q	Neutral	0.209
NOTCH3	Q9UM47-1.2	R1693S	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	R1693T	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	R1693V	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	R1693W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1693Y	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	R1694A	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	R1694C	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	R1694D	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	R1694E	Pathogenic	0.528
NOTCH3	Q9UM47-1.2	R1694F	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1694G	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	R1694H	Pathogenic	0.539
NOTCH3	Q9UM47-1.2	R1694I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	R1694K	Neutral	0.056
NOTCH3	Q9UM47-1.2	R1694L	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	R1694M	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	R1694N	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	R1694P	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	R1694Q	Neutral	0.201
NOTCH3	Q9UM47-1.2	R1694S	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	R1694T	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	R1694V	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	R1694W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1694Y	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	E1695A	Pathogenic	0.647
NOTCH3	Q9UM47-1.2	E1695C	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	E1695D	Neutral	0.021
NOTCH3	Q9UM47-1.2	E1695F	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	E1695G	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	E1695H	Neutral	0.314
NOTCH3	Q9UM47-1.2	E1695I	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	E1695K	Neutral	0.086
NOTCH3	Q9UM47-1.2	E1695L	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	E1695M	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	E1695N	Neutral	0.309
NOTCH3	Q9UM47-1.2	E1695P	Pathogenic	0.668
NOTCH3	Q9UM47-1.2	E1695Q	Neutral	0.022
NOTCH3	Q9UM47-1.2	E1695R	Neutral	0.289
NOTCH3	Q9UM47-1.2	E1695S	Neutral	0.291
NOTCH3	Q9UM47-1.2	E1695T	Pathogenic	0.67
NOTCH3	Q9UM47-1.2	E1695V	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	E1695W	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	E1695Y	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	P1696A	Pathogenic	0.582
NOTCH3	Q9UM47-1.2	P1696C	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	P1696D	Pathogenic	0.604
NOTCH3	Q9UM47-1.2	P1696E	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	P1696F	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	P1696G	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	P1696H	Pathogenic	0.862
NOTCH3	Q9UM47-1.2	P1696I	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	P1696K	Pathogenic	0.564
NOTCH3	Q9UM47-1.2	P1696L	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	P1696M	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	P1696N	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	P1696Q	Pathogenic	0.582
NOTCH3	Q9UM47-1.2	P1696R	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	P1696S	Pathogenic	0.588
NOTCH3	Q9UM47-1.2	P1696T	Pathogenic	0.601
NOTCH3	Q9UM47-1.2	P1696V	Pathogenic	0.867
NOTCH3	Q9UM47-1.2	P1696W	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	P1696Y	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	V1697A	Neutral	0.123
NOTCH3	Q9UM47-1.2	V1697C	Neutral	0.405
NOTCH3	Q9UM47-1.2	V1697D	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	V1697E	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	V1697F	Neutral	0.396
NOTCH3	Q9UM47-1.2	V1697G	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	V1697H	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	V1697I	Neutral	0.002
NOTCH3	Q9UM47-1.2	V1697K	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	V1697L	Neutral	0.032
NOTCH3	Q9UM47-1.2	V1697M	Neutral	0.032
NOTCH3	Q9UM47-1.2	V1697N	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	V1697P	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	V1697Q	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	V1697R	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	V1697S	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	V1697T	Neutral	0.134
NOTCH3	Q9UM47-1.2	V1697W	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	V1697Y	Neutral	0.389
NOTCH3	Q9UM47-1.2	G1698A	Neutral	0.218
NOTCH3	Q9UM47-1.2	G1698C	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G1698D	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	G1698E	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	G1698F	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G1698H	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	G1698I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1698K	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	G1698L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1698M	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G1698N	Neutral	0.2
NOTCH3	Q9UM47-1.2	G1698P	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	G1698Q	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	G1698R	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	G1698S	Neutral	0.214
NOTCH3	Q9UM47-1.2	G1698T	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	G1698V	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G1698W	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	G1698Y	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	Q1699A	Neutral	0.35
NOTCH3	Q9UM47-1.2	Q1699C	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	Q1699D	Neutral	0.115
NOTCH3	Q9UM47-1.2	Q1699E	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q1699F	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	Q1699G	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	Q1699H	Neutral	0.122
NOTCH3	Q9UM47-1.2	Q1699I	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	Q1699K	Neutral	0.028
NOTCH3	Q9UM47-1.2	Q1699L	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	Q1699M	Neutral	0.121
NOTCH3	Q9UM47-1.2	Q1699N	Neutral	0.117
NOTCH3	Q9UM47-1.2	Q1699P	Neutral	0.371
NOTCH3	Q9UM47-1.2	Q1699R	Neutral	0.027
NOTCH3	Q9UM47-1.2	Q1699S	Neutral	0.108
NOTCH3	Q9UM47-1.2	Q1699T	Neutral	0.373
NOTCH3	Q9UM47-1.2	Q1699V	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	Q1699W	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	Q1699Y	Neutral	0.369
NOTCH3	Q9UM47-1.2	D1700A	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	D1700C	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	D1700E	Neutral	0.021
NOTCH3	Q9UM47-1.2	D1700F	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	D1700G	Pathogenic	0.644
NOTCH3	Q9UM47-1.2	D1700H	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	D1700I	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	D1700K	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	D1700L	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	D1700M	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	D1700N	Neutral	0.091
NOTCH3	Q9UM47-1.2	D1700P	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	D1700Q	Neutral	0.3
NOTCH3	Q9UM47-1.2	D1700R	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	D1700S	Neutral	0.305
NOTCH3	Q9UM47-1.2	D1700T	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	D1700V	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	D1700W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	D1700Y	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	A1701C	Neutral	0.038
NOTCH3	Q9UM47-1.2	A1701D	Neutral	0.449
NOTCH3	Q9UM47-1.2	A1701E	Neutral	0.143
NOTCH3	Q9UM47-1.2	A1701F	Neutral	0.408
NOTCH3	Q9UM47-1.2	A1701G	Neutral	0.038
NOTCH3	Q9UM47-1.2	A1701H	Neutral	0.422
NOTCH3	Q9UM47-1.2	A1701I	Neutral	0.137
NOTCH3	Q9UM47-1.2	A1701K	Neutral	0.131
NOTCH3	Q9UM47-1.2	A1701L	Neutral	0.136
NOTCH3	Q9UM47-1.2	A1701M	Neutral	0.136
NOTCH3	Q9UM47-1.2	A1701N	Neutral	0.444
NOTCH3	Q9UM47-1.2	A1701P	Neutral	0.152
NOTCH3	Q9UM47-1.2	A1701Q	Neutral	0.14
NOTCH3	Q9UM47-1.2	A1701R	Neutral	0.126
NOTCH3	Q9UM47-1.2	A1701S	Neutral	0.009
NOTCH3	Q9UM47-1.2	A1701T	Neutral	0.037
NOTCH3	Q9UM47-1.2	A1701V	Neutral	0.036
NOTCH3	Q9UM47-1.2	A1701W	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	A1701Y	Neutral	0.401
NOTCH3	Q9UM47-1.2	L1702A	Neutral	0.039
NOTCH3	Q9UM47-1.2	L1702C	Neutral	0.042
NOTCH3	Q9UM47-1.2	L1702D	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	L1702E	Neutral	0.499
NOTCH3	Q9UM47-1.2	L1702F	Neutral	0.01
NOTCH3	Q9UM47-1.2	L1702G	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	L1702H	Pathogenic	0.506
NOTCH3	Q9UM47-1.2	L1702I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1702K	Neutral	0.182
NOTCH3	Q9UM47-1.2	L1702M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1702N	Neutral	0.486
NOTCH3	Q9UM47-1.2	L1702P	Neutral	0.478
NOTCH3	Q9UM47-1.2	L1702Q	Neutral	0.182
NOTCH3	Q9UM47-1.2	L1702R	Neutral	0.175
NOTCH3	Q9UM47-1.2	L1702S	Neutral	0.159
NOTCH3	Q9UM47-1.2	L1702T	Neutral	0.043
NOTCH3	Q9UM47-1.2	L1702V	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1702W	Neutral	0.164
NOTCH3	Q9UM47-1.2	L1702Y	Neutral	0.045
NOTCH3	Q9UM47-1.2	G1703A	Neutral	0.098
NOTCH3	Q9UM47-1.2	G1703C	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	G1703D	Neutral	0.31
NOTCH3	Q9UM47-1.2	G1703E	Pathogenic	0.656
NOTCH3	Q9UM47-1.2	G1703F	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	G1703H	Pathogenic	0.648
NOTCH3	Q9UM47-1.2	G1703I	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	G1703K	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	G1703L	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	G1703M	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	G1703N	Neutral	0.088
NOTCH3	Q9UM47-1.2	G1703P	Pathogenic	0.673
NOTCH3	Q9UM47-1.2	G1703Q	Pathogenic	0.651
NOTCH3	Q9UM47-1.2	G1703R	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	G1703S	Neutral	0.095
NOTCH3	Q9UM47-1.2	G1703T	Pathogenic	0.669
NOTCH3	Q9UM47-1.2	G1703V	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	G1703W	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	G1703Y	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	M1704A	Pathogenic	0.624
NOTCH3	Q9UM47-1.2	M1704C	Pathogenic	0.64
NOTCH3	Q9UM47-1.2	M1704D	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	M1704E	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	M1704F	Neutral	0.303
NOTCH3	Q9UM47-1.2	M1704G	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	M1704H	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	M1704I	Neutral	0.091
NOTCH3	Q9UM47-1.2	M1704K	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	M1704L	Neutral	0.021
NOTCH3	Q9UM47-1.2	M1704N	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	M1704P	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	M1704Q	Neutral	0.305
NOTCH3	Q9UM47-1.2	M1704R	Pathogenic	0.656
NOTCH3	Q9UM47-1.2	M1704S	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	M1704T	Pathogenic	0.648
NOTCH3	Q9UM47-1.2	M1704V	Neutral	0.084
NOTCH3	Q9UM47-1.2	M1704W	Pathogenic	0.641
NOTCH3	Q9UM47-1.2	M1704Y	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	K1705A	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	K1705C	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	K1705D	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	K1705E	Neutral	0.237
NOTCH3	Q9UM47-1.2	K1705F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	K1705G	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	K1705H	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	K1705I	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	K1705L	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	K1705M	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	K1705N	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	K1705P	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	K1705Q	Neutral	0.241
NOTCH3	Q9UM47-1.2	K1705R	Neutral	0.067
NOTCH3	Q9UM47-1.2	K1705S	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	K1705T	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	K1705V	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	K1705W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	K1705Y	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	N1706A	Pathogenic	0.588
NOTCH3	Q9UM47-1.2	N1706C	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	N1706D	Neutral	0.016
NOTCH3	Q9UM47-1.2	N1706E	Neutral	0.068
NOTCH3	Q9UM47-1.2	N1706F	Pathogenic	0.864
NOTCH3	Q9UM47-1.2	N1706G	Neutral	0.06
NOTCH3	Q9UM47-1.2	N1706H	Neutral	0.015
NOTCH3	Q9UM47-1.2	N1706I	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	N1706K	Neutral	0.062
NOTCH3	Q9UM47-1.2	N1706L	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	N1706M	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	N1706P	Pathogenic	0.61
NOTCH3	Q9UM47-1.2	N1706Q	Neutral	0.067
NOTCH3	Q9UM47-1.2	N1706R	Neutral	0.059
NOTCH3	Q9UM47-1.2	N1706S	Neutral	0.015
NOTCH3	Q9UM47-1.2	N1706T	Neutral	0.071
NOTCH3	Q9UM47-1.2	N1706V	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	N1706W	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	N1706Y	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	M1707A	Neutral	0.5
NOTCH3	Q9UM47-1.2	M1707C	Pathogenic	0.517
NOTCH3	Q9UM47-1.2	M1707D	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	M1707E	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	M1707F	Neutral	0.207
NOTCH3	Q9UM47-1.2	M1707G	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	M1707H	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	M1707I	Neutral	0.056
NOTCH3	Q9UM47-1.2	M1707K	Pathogenic	0.547
NOTCH3	Q9UM47-1.2	M1707L	Neutral	0.013
NOTCH3	Q9UM47-1.2	M1707N	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	M1707P	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	M1707Q	Neutral	0.209
NOTCH3	Q9UM47-1.2	M1707R	Pathogenic	0.534
NOTCH3	Q9UM47-1.2	M1707S	Pathogenic	0.506
NOTCH3	Q9UM47-1.2	M1707T	Pathogenic	0.525
NOTCH3	Q9UM47-1.2	M1707V	Neutral	0.052
NOTCH3	Q9UM47-1.2	M1707W	Pathogenic	0.517
NOTCH3	Q9UM47-1.2	M1707Y	Pathogenic	0.537
NOTCH3	Q9UM47-1.2	A1708C	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1708D	Neutral	0.089
NOTCH3	Q9UM47-1.2	A1708E	Neutral	0.02
NOTCH3	Q9UM47-1.2	A1708F	Neutral	0.076
NOTCH3	Q9UM47-1.2	A1708G	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1708H	Neutral	0.08
NOTCH3	Q9UM47-1.2	A1708I	Neutral	0.019
NOTCH3	Q9UM47-1.2	A1708K	Neutral	0.018
NOTCH3	Q9UM47-1.2	A1708L	Neutral	0.019
NOTCH3	Q9UM47-1.2	A1708M	Neutral	0.018
NOTCH3	Q9UM47-1.2	A1708N	Neutral	0.087
NOTCH3	Q9UM47-1.2	A1708P	Neutral	0.021
NOTCH3	Q9UM47-1.2	A1708Q	Neutral	0.019
NOTCH3	Q9UM47-1.2	A1708R	Neutral	0.017
NOTCH3	Q9UM47-1.2	A1708S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1708T	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1708V	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1708W	Neutral	0.253
NOTCH3	Q9UM47-1.2	A1708Y	Neutral	0.074
NOTCH3	Q9UM47-1.2	K1709A	Pathogenic	0.592
NOTCH3	Q9UM47-1.2	K1709C	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	K1709D	Pathogenic	0.612
NOTCH3	Q9UM47-1.2	K1709E	Neutral	0.076
NOTCH3	Q9UM47-1.2	K1709F	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	K1709G	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	K1709H	Pathogenic	0.639
NOTCH3	Q9UM47-1.2	K1709I	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	K1709L	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	K1709M	Pathogenic	0.646
NOTCH3	Q9UM47-1.2	K1709N	Neutral	0.262
NOTCH3	Q9UM47-1.2	K1709P	Pathogenic	0.614
NOTCH3	Q9UM47-1.2	K1709Q	Neutral	0.077
NOTCH3	Q9UM47-1.2	K1709R	Neutral	0.018
NOTCH3	Q9UM47-1.2	K1709S	Neutral	0.246
NOTCH3	Q9UM47-1.2	K1709T	Pathogenic	0.616
NOTCH3	Q9UM47-1.2	K1709V	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	K1709W	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	K1709Y	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	G1710A	Neutral	0.001
NOTCH3	Q9UM47-1.2	G1710C	Neutral	0.113
NOTCH3	Q9UM47-1.2	G1710D	Neutral	0.006
NOTCH3	Q9UM47-1.2	G1710E	Neutral	0.025
NOTCH3	Q9UM47-1.2	G1710F	Neutral	0.096
NOTCH3	Q9UM47-1.2	G1710H	Neutral	0.024
NOTCH3	Q9UM47-1.2	G1710I	Neutral	0.335
NOTCH3	Q9UM47-1.2	G1710K	Neutral	0.023
NOTCH3	Q9UM47-1.2	G1710L	Neutral	0.335
NOTCH3	Q9UM47-1.2	G1710M	Neutral	0.099
NOTCH3	Q9UM47-1.2	G1710N	Neutral	0.001
NOTCH3	Q9UM47-1.2	G1710P	Neutral	0.027
NOTCH3	Q9UM47-1.2	G1710Q	Neutral	0.024
NOTCH3	Q9UM47-1.2	G1710R	Neutral	0.022
NOTCH3	Q9UM47-1.2	G1710S	Neutral	0.001
NOTCH3	Q9UM47-1.2	G1710T	Neutral	0.026
NOTCH3	Q9UM47-1.2	G1710V	Neutral	0.106
NOTCH3	Q9UM47-1.2	G1710W	Neutral	0.021
NOTCH3	Q9UM47-1.2	G1710Y	Neutral	0.093
NOTCH3	Q9UM47-1.2	E1711A	Neutral	0.014
NOTCH3	Q9UM47-1.2	E1711C	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	E1711D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1711F	Neutral	0.237
NOTCH3	Q9UM47-1.2	E1711G	Neutral	0.056
NOTCH3	Q9UM47-1.2	E1711H	Neutral	0.003
NOTCH3	Q9UM47-1.2	E1711I	Neutral	0.245
NOTCH3	Q9UM47-1.2	E1711K	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1711L	Neutral	0.245
NOTCH3	Q9UM47-1.2	E1711M	Neutral	0.066
NOTCH3	Q9UM47-1.2	E1711N	Neutral	0.003
NOTCH3	Q9UM47-1.2	E1711P	Neutral	0.015
NOTCH3	Q9UM47-1.2	E1711Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1711R	Neutral	0.003
NOTCH3	Q9UM47-1.2	E1711S	Neutral	0.003
NOTCH3	Q9UM47-1.2	E1711T	Neutral	0.015
NOTCH3	Q9UM47-1.2	E1711V	Neutral	0.069
NOTCH3	Q9UM47-1.2	E1711W	Neutral	0.219
NOTCH3	Q9UM47-1.2	E1711Y	Neutral	0.062
NOTCH3	Q9UM47-1.2	S1712A	Neutral	0.019
NOTCH3	Q9UM47-1.2	S1712C	Neutral	0.286
NOTCH3	Q9UM47-1.2	S1712D	Neutral	0.079
NOTCH3	Q9UM47-1.2	S1712E	Neutral	0.074
NOTCH3	Q9UM47-1.2	S1712F	Pathogenic	0.603
NOTCH3	Q9UM47-1.2	S1712G	Neutral	0.077
NOTCH3	Q9UM47-1.2	S1712H	Neutral	0.26
NOTCH3	Q9UM47-1.2	S1712I	Pathogenic	0.613
NOTCH3	Q9UM47-1.2	S1712K	Neutral	0.068
NOTCH3	Q9UM47-1.2	S1712L	Pathogenic	0.613
NOTCH3	Q9UM47-1.2	S1712M	Neutral	0.257
NOTCH3	Q9UM47-1.2	S1712N	Neutral	0.018
NOTCH3	Q9UM47-1.2	S1712P	Neutral	0.282
NOTCH3	Q9UM47-1.2	S1712Q	Neutral	0.073
NOTCH3	Q9UM47-1.2	S1712R	Neutral	0.24
NOTCH3	Q9UM47-1.2	S1712T	Neutral	0.018
NOTCH3	Q9UM47-1.2	S1712V	Pathogenic	0.629
NOTCH3	Q9UM47-1.2	S1712W	Pathogenic	0.862
NOTCH3	Q9UM47-1.2	S1712Y	Pathogenic	0.596
NOTCH3	Q9UM47-1.2	L1713A	Neutral	0.437
NOTCH3	Q9UM47-1.2	L1713C	Neutral	0.453
NOTCH3	Q9UM47-1.2	L1713D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	L1713E	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	L1713F	Neutral	0.167
NOTCH3	Q9UM47-1.2	L1713G	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	L1713H	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	L1713I	Neutral	0.01
NOTCH3	Q9UM47-1.2	L1713K	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	L1713M	Neutral	0.01
NOTCH3	Q9UM47-1.2	L1713N	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	L1713P	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	L1713Q	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	L1713R	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	L1713S	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	L1713T	Neutral	0.461
NOTCH3	Q9UM47-1.2	L1713V	Neutral	0.041
NOTCH3	Q9UM47-1.2	L1713W	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	L1713Y	Neutral	0.473
NOTCH3	Q9UM47-1.2	M1714A	Pathogenic	0.675
NOTCH3	Q9UM47-1.2	M1714C	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	M1714D	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	M1714E	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	M1714F	Neutral	0.352
NOTCH3	Q9UM47-1.2	M1714G	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	M1714H	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	M1714I	Neutral	0.111
NOTCH3	Q9UM47-1.2	M1714K	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	M1714L	Neutral	0.027
NOTCH3	Q9UM47-1.2	M1714N	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	M1714P	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	M1714Q	Neutral	0.355
NOTCH3	Q9UM47-1.2	M1714R	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	M1714S	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	M1714T	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	M1714V	Neutral	0.103
NOTCH3	Q9UM47-1.2	M1714W	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	M1714Y	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	G1715A	Neutral	0.02
NOTCH3	Q9UM47-1.2	G1715C	Pathogenic	0.638
NOTCH3	Q9UM47-1.2	G1715D	Neutral	0.077
NOTCH3	Q9UM47-1.2	G1715E	Neutral	0.261
NOTCH3	Q9UM47-1.2	G1715F	Pathogenic	0.595
NOTCH3	Q9UM47-1.2	G1715H	Neutral	0.254
NOTCH3	Q9UM47-1.2	G1715I	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	G1715K	Neutral	0.243
NOTCH3	Q9UM47-1.2	G1715L	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	G1715M	Pathogenic	0.604
NOTCH3	Q9UM47-1.2	G1715N	Neutral	0.018
NOTCH3	Q9UM47-1.2	G1715P	Neutral	0.275
NOTCH3	Q9UM47-1.2	G1715Q	Neutral	0.257
NOTCH3	Q9UM47-1.2	G1715R	Neutral	0.234
NOTCH3	Q9UM47-1.2	G1715S	Neutral	0.019
NOTCH3	Q9UM47-1.2	G1715T	Neutral	0.272
NOTCH3	Q9UM47-1.2	G1715V	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	G1715W	Neutral	0.225
NOTCH3	Q9UM47-1.2	G1715Y	Pathogenic	0.588
NOTCH3	Q9UM47-1.2	E1716A	Neutral	0.022
NOTCH3	Q9UM47-1.2	E1716C	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	E1716D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1716F	Neutral	0.33
NOTCH3	Q9UM47-1.2	E1716G	Neutral	0.085
NOTCH3	Q9UM47-1.2	E1716H	Neutral	0.005
NOTCH3	Q9UM47-1.2	E1716I	Neutral	0.34
NOTCH3	Q9UM47-1.2	E1716K	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1716L	Neutral	0.339
NOTCH3	Q9UM47-1.2	E1716M	Neutral	0.101
NOTCH3	Q9UM47-1.2	E1716N	Neutral	0.005
NOTCH3	Q9UM47-1.2	E1716P	Neutral	0.024
NOTCH3	Q9UM47-1.2	E1716Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E1716R	Neutral	0.005
NOTCH3	Q9UM47-1.2	E1716S	Neutral	0.005
NOTCH3	Q9UM47-1.2	E1716T	Neutral	0.024
NOTCH3	Q9UM47-1.2	E1716V	Neutral	0.105
NOTCH3	Q9UM47-1.2	E1716W	Neutral	0.308
NOTCH3	Q9UM47-1.2	E1716Y	Neutral	0.095
NOTCH3	Q9UM47-1.2	V1717A	Neutral	0.006
NOTCH3	Q9UM47-1.2	V1717C	Neutral	0.031
NOTCH3	Q9UM47-1.2	V1717D	Neutral	0.403
NOTCH3	Q9UM47-1.2	V1717E	Neutral	0.133
NOTCH3	Q9UM47-1.2	V1717F	Neutral	0.029
NOTCH3	Q9UM47-1.2	V1717G	Neutral	0.362
NOTCH3	Q9UM47-1.2	V1717H	Neutral	0.402
NOTCH3	Q9UM47-1.2	V1717I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V1717K	Neutral	0.123
NOTCH3	Q9UM47-1.2	V1717L	Neutral	0.002
NOTCH3	Q9UM47-1.2	V1717M	Neutral	0.002
NOTCH3	Q9UM47-1.2	V1717N	Neutral	0.407
NOTCH3	Q9UM47-1.2	V1717P	Neutral	0.127
NOTCH3	Q9UM47-1.2	V1717Q	Neutral	0.131
NOTCH3	Q9UM47-1.2	V1717R	Neutral	0.377
NOTCH3	Q9UM47-1.2	V1717S	Neutral	0.121
NOTCH3	Q9UM47-1.2	V1717T	Neutral	0.007
NOTCH3	Q9UM47-1.2	V1717W	Neutral	0.361
NOTCH3	Q9UM47-1.2	V1717Y	Neutral	0.029
NOTCH3	Q9UM47-1.2	A1718C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1718D	Neutral	0.054
NOTCH3	Q9UM47-1.2	A1718E	Neutral	0.012
NOTCH3	Q9UM47-1.2	A1718F	Neutral	0.046
NOTCH3	Q9UM47-1.2	A1718G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1718H	Neutral	0.049
NOTCH3	Q9UM47-1.2	A1718I	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1718K	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1718L	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1718M	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1718N	Neutral	0.053
NOTCH3	Q9UM47-1.2	A1718P	Neutral	0.012
NOTCH3	Q9UM47-1.2	A1718Q	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1718R	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1718S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1718T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1718V	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1718W	Neutral	0.166
NOTCH3	Q9UM47-1.2	A1718Y	Neutral	0.045
NOTCH3	Q9UM47-1.2	T1719A	Neutral	0.008
NOTCH3	Q9UM47-1.2	T1719C	Neutral	0.037
NOTCH3	Q9UM47-1.2	T1719D	Neutral	0.038
NOTCH3	Q9UM47-1.2	T1719E	Neutral	0.036
NOTCH3	Q9UM47-1.2	T1719F	Neutral	0.132
NOTCH3	Q9UM47-1.2	T1719G	Neutral	0.13
NOTCH3	Q9UM47-1.2	T1719H	Neutral	0.139
NOTCH3	Q9UM47-1.2	T1719I	Neutral	0.034
NOTCH3	Q9UM47-1.2	T1719K	Neutral	0.032
NOTCH3	Q9UM47-1.2	T1719L	Neutral	0.034
NOTCH3	Q9UM47-1.2	T1719M	Neutral	0.034
NOTCH3	Q9UM47-1.2	T1719N	Neutral	0.008
NOTCH3	Q9UM47-1.2	T1719P	Neutral	0.037
NOTCH3	Q9UM47-1.2	T1719Q	Neutral	0.035
NOTCH3	Q9UM47-1.2	T1719R	Neutral	0.031
NOTCH3	Q9UM47-1.2	T1719S	Neutral	0.002
NOTCH3	Q9UM47-1.2	T1719V	Neutral	0.008
NOTCH3	Q9UM47-1.2	T1719W	Neutral	0.121
NOTCH3	Q9UM47-1.2	T1719Y	Neutral	0.129
NOTCH3	Q9UM47-1.2	D1720A	Neutral	0.226
NOTCH3	Q9UM47-1.2	D1720C	Pathogenic	0.59
NOTCH3	Q9UM47-1.2	D1720E	Neutral	0.001
NOTCH3	Q9UM47-1.2	D1720F	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	D1720G	Neutral	0.056
NOTCH3	Q9UM47-1.2	D1720H	Neutral	0.059
NOTCH3	Q9UM47-1.2	D1720I	Pathogenic	0.565
NOTCH3	Q9UM47-1.2	D1720K	Neutral	0.056
NOTCH3	Q9UM47-1.2	D1720L	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	D1720M	Pathogenic	0.564
NOTCH3	Q9UM47-1.2	D1720N	Neutral	0.003
NOTCH3	Q9UM47-1.2	D1720P	Neutral	0.066
NOTCH3	Q9UM47-1.2	D1720Q	Neutral	0.014
NOTCH3	Q9UM47-1.2	D1720R	Neutral	0.203
NOTCH3	Q9UM47-1.2	D1720S	Neutral	0.014
NOTCH3	Q9UM47-1.2	D1720T	Neutral	0.065
NOTCH3	Q9UM47-1.2	D1720V	Pathogenic	0.582
NOTCH3	Q9UM47-1.2	D1720W	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	D1720Y	Pathogenic	0.547
NOTCH3	Q9UM47-1.2	W1721A	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1721C	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1721D	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1721E	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1721F	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	W1721G	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1721H	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1721I	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1721K	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1721L	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1721M	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	W1721N	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1721P	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1721Q	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1721R	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1721S	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1721T	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1721V	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1721Y	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	M1722A	Neutral	0.146
NOTCH3	Q9UM47-1.2	M1722C	Neutral	0.155
NOTCH3	Q9UM47-1.2	M1722D	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	M1722E	Neutral	0.481
NOTCH3	Q9UM47-1.2	M1722F	Neutral	0.043
NOTCH3	Q9UM47-1.2	M1722G	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	M1722H	Neutral	0.488
NOTCH3	Q9UM47-1.2	M1722I	Neutral	0.01
NOTCH3	Q9UM47-1.2	M1722K	Neutral	0.172
NOTCH3	Q9UM47-1.2	M1722L	Neutral	0.002
NOTCH3	Q9UM47-1.2	M1722N	Neutral	0.468
NOTCH3	Q9UM47-1.2	M1722P	Neutral	0.46
NOTCH3	Q9UM47-1.2	M1722Q	Neutral	0.043
NOTCH3	Q9UM47-1.2	M1722R	Neutral	0.165
NOTCH3	Q9UM47-1.2	M1722S	Neutral	0.15
NOTCH3	Q9UM47-1.2	M1722T	Neutral	0.159
NOTCH3	Q9UM47-1.2	M1722V	Neutral	0.009
NOTCH3	Q9UM47-1.2	M1722W	Neutral	0.155
NOTCH3	Q9UM47-1.2	M1722Y	Neutral	0.166
NOTCH3	Q9UM47-1.2	D1723A	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	D1723C	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	D1723E	Neutral	0.011
NOTCH3	Q9UM47-1.2	D1723F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	D1723G	Neutral	0.487
NOTCH3	Q9UM47-1.2	D1723H	Pathogenic	0.502
NOTCH3	Q9UM47-1.2	D1723I	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	D1723K	Neutral	0.484
NOTCH3	Q9UM47-1.2	D1723L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	D1723M	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	D1723N	Neutral	0.05
NOTCH3	Q9UM47-1.2	D1723P	Pathogenic	0.528
NOTCH3	Q9UM47-1.2	D1723Q	Neutral	0.183
NOTCH3	Q9UM47-1.2	D1723R	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	D1723S	Neutral	0.186
NOTCH3	Q9UM47-1.2	D1723T	Pathogenic	0.527
NOTCH3	Q9UM47-1.2	D1723V	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	D1723W	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	D1723Y	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	T1724A	Neutral	0.007
NOTCH3	Q9UM47-1.2	T1724C	Neutral	0.031
NOTCH3	Q9UM47-1.2	T1724D	Neutral	0.032
NOTCH3	Q9UM47-1.2	T1724E	Neutral	0.03
NOTCH3	Q9UM47-1.2	T1724F	Neutral	0.115
NOTCH3	Q9UM47-1.2	T1724G	Neutral	0.113
NOTCH3	Q9UM47-1.2	T1724H	Neutral	0.12
NOTCH3	Q9UM47-1.2	T1724I	Neutral	0.029
NOTCH3	Q9UM47-1.2	T1724K	Neutral	0.028
NOTCH3	Q9UM47-1.2	T1724L	Neutral	0.029
NOTCH3	Q9UM47-1.2	T1724M	Neutral	0.029
NOTCH3	Q9UM47-1.2	T1724N	Neutral	0.007
NOTCH3	Q9UM47-1.2	T1724P	Neutral	0.032
NOTCH3	Q9UM47-1.2	T1724Q	Neutral	0.03
NOTCH3	Q9UM47-1.2	T1724R	Neutral	0.026
NOTCH3	Q9UM47-1.2	T1724S	Neutral	0.001
NOTCH3	Q9UM47-1.2	T1724V	Neutral	0.007
NOTCH3	Q9UM47-1.2	T1724W	Neutral	0.105
NOTCH3	Q9UM47-1.2	T1724Y	Neutral	0.112
NOTCH3	Q9UM47-1.2	E1725A	Neutral	0.305
NOTCH3	Q9UM47-1.2	E1725C	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	E1725D	Neutral	0.005
NOTCH3	Q9UM47-1.2	E1725F	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	E1725G	Pathogenic	0.649
NOTCH3	Q9UM47-1.2	E1725H	Neutral	0.098
NOTCH3	Q9UM47-1.2	E1725I	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	E1725K	Neutral	0.022
NOTCH3	Q9UM47-1.2	E1725L	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	E1725M	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	E1725N	Neutral	0.097
NOTCH3	Q9UM47-1.2	E1725P	Neutral	0.325
NOTCH3	Q9UM47-1.2	E1725Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	E1725R	Neutral	0.088
NOTCH3	Q9UM47-1.2	E1725S	Neutral	0.089
NOTCH3	Q9UM47-1.2	E1725T	Neutral	0.326
NOTCH3	Q9UM47-1.2	E1725V	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	E1725W	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	E1725Y	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	C1726A	Neutral	0.003
NOTCH3	Q9UM47-1.2	C1726D	Neutral	0.207
NOTCH3	Q9UM47-1.2	C1726E	Pathogenic	0.526
NOTCH3	Q9UM47-1.2	C1726F	Neutral	0.046
NOTCH3	Q9UM47-1.2	C1726G	Neutral	0.186
NOTCH3	Q9UM47-1.2	C1726H	Neutral	0.19
NOTCH3	Q9UM47-1.2	C1726I	Neutral	0.011
NOTCH3	Q9UM47-1.2	C1726K	Neutral	0.181
NOTCH3	Q9UM47-1.2	C1726L	Neutral	0.011
NOTCH3	Q9UM47-1.2	C1726M	Neutral	0.011
NOTCH3	Q9UM47-1.2	C1726N	Neutral	0.204
NOTCH3	Q9UM47-1.2	C1726P	Neutral	0.206
NOTCH3	Q9UM47-1.2	C1726Q	Neutral	0.192
NOTCH3	Q9UM47-1.2	C1726R	Neutral	0.174
NOTCH3	Q9UM47-1.2	C1726S	Neutral	0.012
NOTCH3	Q9UM47-1.2	C1726T	Neutral	0.012
NOTCH3	Q9UM47-1.2	C1726V	Neutral	0.012
NOTCH3	Q9UM47-1.2	C1726W	Neutral	0.042
NOTCH3	Q9UM47-1.2	C1726Y	Neutral	0.045
NOTCH3	Q9UM47-1.2	P1727A	Neutral	0.221
NOTCH3	Q9UM47-1.2	P1727C	Pathogenic	0.864
NOTCH3	Q9UM47-1.2	P1727D	Neutral	0.238
NOTCH3	Q9UM47-1.2	P1727E	Neutral	0.225
NOTCH3	Q9UM47-1.2	P1727F	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	P1727G	Pathogenic	0.546
NOTCH3	Q9UM47-1.2	P1727H	Pathogenic	0.56
NOTCH3	Q9UM47-1.2	P1727I	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	P1727K	Neutral	0.209
NOTCH3	Q9UM47-1.2	P1727L	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	P1727M	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	P1727N	Pathogenic	0.582
NOTCH3	Q9UM47-1.2	P1727Q	Neutral	0.221
NOTCH3	Q9UM47-1.2	P1727R	Pathogenic	0.533
NOTCH3	Q9UM47-1.2	P1727S	Neutral	0.226
NOTCH3	Q9UM47-1.2	P1727T	Neutral	0.235
NOTCH3	Q9UM47-1.2	P1727V	Pathogenic	0.572
NOTCH3	Q9UM47-1.2	P1727W	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	P1727Y	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	E1728A	Neutral	0.145
NOTCH3	Q9UM47-1.2	E1728C	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	E1728D	Neutral	0.002
NOTCH3	Q9UM47-1.2	E1728F	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	E1728G	Neutral	0.417
NOTCH3	Q9UM47-1.2	E1728H	Neutral	0.041
NOTCH3	Q9UM47-1.2	E1728I	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	E1728K	Neutral	0.009
NOTCH3	Q9UM47-1.2	E1728L	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	E1728M	Neutral	0.464
NOTCH3	Q9UM47-1.2	E1728N	Neutral	0.04
NOTCH3	Q9UM47-1.2	E1728P	Neutral	0.157
NOTCH3	Q9UM47-1.2	E1728Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	E1728R	Neutral	0.036
NOTCH3	Q9UM47-1.2	E1728S	Neutral	0.037
NOTCH3	Q9UM47-1.2	E1728T	Neutral	0.158
NOTCH3	Q9UM47-1.2	E1728V	Neutral	0.474
NOTCH3	Q9UM47-1.2	E1728W	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	E1728Y	Neutral	0.447
NOTCH3	Q9UM47-1.2	A1729C	Neutral	0.012
NOTCH3	Q9UM47-1.2	A1729D	Neutral	0.193
NOTCH3	Q9UM47-1.2	A1729E	Neutral	0.047
NOTCH3	Q9UM47-1.2	A1729F	Neutral	0.168
NOTCH3	Q9UM47-1.2	A1729G	Neutral	0.012
NOTCH3	Q9UM47-1.2	A1729H	Neutral	0.176
NOTCH3	Q9UM47-1.2	A1729I	Neutral	0.044
NOTCH3	Q9UM47-1.2	A1729K	Neutral	0.042
NOTCH3	Q9UM47-1.2	A1729L	Neutral	0.044
NOTCH3	Q9UM47-1.2	A1729M	Neutral	0.044
NOTCH3	Q9UM47-1.2	A1729N	Neutral	0.19
NOTCH3	Q9UM47-1.2	A1729P	Neutral	0.05
NOTCH3	Q9UM47-1.2	A1729Q	Neutral	0.046
NOTCH3	Q9UM47-1.2	A1729R	Neutral	0.04
NOTCH3	Q9UM47-1.2	A1729S	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1729T	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1729V	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1729W	Neutral	0.453
NOTCH3	Q9UM47-1.2	A1729Y	Neutral	0.164
NOTCH3	Q9UM47-1.2	K1730A	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	K1730C	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	K1730D	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	K1730E	Neutral	0.313
NOTCH3	Q9UM47-1.2	K1730F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	K1730G	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	K1730H	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	K1730I	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	K1730L	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	K1730M	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	K1730N	Pathogenic	0.663
NOTCH3	Q9UM47-1.2	K1730P	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	K1730Q	Neutral	0.318
NOTCH3	Q9UM47-1.2	K1730R	Neutral	0.095
NOTCH3	Q9UM47-1.2	K1730S	Pathogenic	0.644
NOTCH3	Q9UM47-1.2	K1730T	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	K1730V	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	K1730W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	K1730Y	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	R1731A	Neutral	0.379
NOTCH3	Q9UM47-1.2	R1731C	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	R1731D	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	R1731E	Neutral	0.135
NOTCH3	Q9UM47-1.2	R1731F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	R1731G	Pathogenic	0.72
NOTCH3	Q9UM47-1.2	R1731H	Neutral	0.14
NOTCH3	Q9UM47-1.2	R1731I	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	R1731K	Neutral	0.008
NOTCH3	Q9UM47-1.2	R1731L	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	R1731M	Neutral	0.433
NOTCH3	Q9UM47-1.2	R1731N	Neutral	0.129
NOTCH3	Q9UM47-1.2	R1731P	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	R1731Q	Neutral	0.034
NOTCH3	Q9UM47-1.2	R1731S	Neutral	0.383
NOTCH3	Q9UM47-1.2	R1731T	Neutral	0.402
NOTCH3	Q9UM47-1.2	R1731V	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	R1731W	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	R1731Y	Pathogenic	0.788
NOTCH3	Q9UM47-1.2	L1732A	Neutral	0.027
NOTCH3	Q9UM47-1.2	L1732C	Neutral	0.028
NOTCH3	Q9UM47-1.2	L1732D	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	L1732E	Neutral	0.401
NOTCH3	Q9UM47-1.2	L1732F	Neutral	0.007
NOTCH3	Q9UM47-1.2	L1732G	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	L1732H	Neutral	0.408
NOTCH3	Q9UM47-1.2	L1732I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1732K	Neutral	0.13
NOTCH3	Q9UM47-1.2	L1732M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1732N	Neutral	0.389
NOTCH3	Q9UM47-1.2	L1732P	Neutral	0.381
NOTCH3	Q9UM47-1.2	L1732Q	Neutral	0.13
NOTCH3	Q9UM47-1.2	L1732R	Neutral	0.125
NOTCH3	Q9UM47-1.2	L1732S	Neutral	0.113
NOTCH3	Q9UM47-1.2	L1732T	Neutral	0.029
NOTCH3	Q9UM47-1.2	L1732V	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1732W	Neutral	0.117
NOTCH3	Q9UM47-1.2	L1732Y	Neutral	0.031
NOTCH3	Q9UM47-1.2	K1733A	Pathogenic	0.613
NOTCH3	Q9UM47-1.2	K1733C	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	K1733D	Pathogenic	0.633
NOTCH3	Q9UM47-1.2	K1733E	Neutral	0.082
NOTCH3	Q9UM47-1.2	K1733F	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	K1733G	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	K1733H	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	K1733I	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	K1733L	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	K1733M	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	K1733N	Neutral	0.279
NOTCH3	Q9UM47-1.2	K1733P	Pathogenic	0.635
NOTCH3	Q9UM47-1.2	K1733Q	Neutral	0.084
NOTCH3	Q9UM47-1.2	K1733R	Neutral	0.02
NOTCH3	Q9UM47-1.2	K1733S	Neutral	0.262
NOTCH3	Q9UM47-1.2	K1733T	Pathogenic	0.637
NOTCH3	Q9UM47-1.2	K1733V	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	K1733W	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	K1733Y	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	V1734A	Neutral	0.009
NOTCH3	Q9UM47-1.2	V1734C	Neutral	0.043
NOTCH3	Q9UM47-1.2	V1734D	Neutral	0.49
NOTCH3	Q9UM47-1.2	V1734E	Neutral	0.18
NOTCH3	Q9UM47-1.2	V1734F	Neutral	0.041
NOTCH3	Q9UM47-1.2	V1734G	Neutral	0.447
NOTCH3	Q9UM47-1.2	V1734H	Neutral	0.489
NOTCH3	Q9UM47-1.2	V1734I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V1734K	Neutral	0.166
NOTCH3	Q9UM47-1.2	V1734L	Neutral	0.002
NOTCH3	Q9UM47-1.2	V1734M	Neutral	0.002
NOTCH3	Q9UM47-1.2	V1734N	Neutral	0.494
NOTCH3	Q9UM47-1.2	V1734P	Neutral	0.172
NOTCH3	Q9UM47-1.2	V1734Q	Neutral	0.176
NOTCH3	Q9UM47-1.2	V1734R	Neutral	0.462
NOTCH3	Q9UM47-1.2	V1734S	Neutral	0.164
NOTCH3	Q9UM47-1.2	V1734T	Neutral	0.01
NOTCH3	Q9UM47-1.2	V1734W	Neutral	0.446
NOTCH3	Q9UM47-1.2	V1734Y	Neutral	0.04
NOTCH3	Q9UM47-1.2	E1735A	Pathogenic	0.608
NOTCH3	Q9UM47-1.2	E1735C	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	E1735D	Neutral	0.018
NOTCH3	Q9UM47-1.2	E1735F	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	E1735G	Pathogenic	0.867
NOTCH3	Q9UM47-1.2	E1735H	Neutral	0.279
NOTCH3	Q9UM47-1.2	E1735I	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	E1735K	Neutral	0.073
NOTCH3	Q9UM47-1.2	E1735L	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	E1735M	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	E1735N	Neutral	0.274
NOTCH3	Q9UM47-1.2	E1735P	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	E1735Q	Neutral	0.019
NOTCH3	Q9UM47-1.2	E1735R	Neutral	0.255
NOTCH3	Q9UM47-1.2	E1735S	Neutral	0.258
NOTCH3	Q9UM47-1.2	E1735T	Pathogenic	0.631
NOTCH3	Q9UM47-1.2	E1735V	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	E1735W	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	E1735Y	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	E1736A	Neutral	0.346
NOTCH3	Q9UM47-1.2	E1736C	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	E1736D	Neutral	0.006
NOTCH3	Q9UM47-1.2	E1736F	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	E1736G	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	E1736H	Neutral	0.116
NOTCH3	Q9UM47-1.2	E1736I	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	E1736K	Neutral	0.026
NOTCH3	Q9UM47-1.2	E1736L	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	E1736M	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	E1736N	Neutral	0.114
NOTCH3	Q9UM47-1.2	E1736P	Neutral	0.367
NOTCH3	Q9UM47-1.2	E1736Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	E1736R	Neutral	0.105
NOTCH3	Q9UM47-1.2	E1736S	Neutral	0.106
NOTCH3	Q9UM47-1.2	E1736T	Neutral	0.369
NOTCH3	Q9UM47-1.2	E1736V	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	E1736W	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	E1736Y	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	P1737A	Neutral	0.071
NOTCH3	Q9UM47-1.2	P1737C	Pathogenic	0.631
NOTCH3	Q9UM47-1.2	P1737D	Neutral	0.078
NOTCH3	Q9UM47-1.2	P1737E	Neutral	0.073
NOTCH3	Q9UM47-1.2	P1737F	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	P1737G	Neutral	0.246
NOTCH3	Q9UM47-1.2	P1737H	Neutral	0.256
NOTCH3	Q9UM47-1.2	P1737I	Pathogenic	0.606
NOTCH3	Q9UM47-1.2	P1737K	Neutral	0.067
NOTCH3	Q9UM47-1.2	P1737L	Pathogenic	0.605
NOTCH3	Q9UM47-1.2	P1737M	Neutral	0.251
NOTCH3	Q9UM47-1.2	P1737N	Neutral	0.273
NOTCH3	Q9UM47-1.2	P1737Q	Neutral	0.071
NOTCH3	Q9UM47-1.2	P1737R	Neutral	0.236
NOTCH3	Q9UM47-1.2	P1737S	Neutral	0.073
NOTCH3	Q9UM47-1.2	P1737T	Neutral	0.077
NOTCH3	Q9UM47-1.2	P1737V	Neutral	0.265
NOTCH3	Q9UM47-1.2	P1737W	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	P1737Y	Pathogenic	0.588
NOTCH3	Q9UM47-1.2	G1738A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1738C	Neutral	0.137
NOTCH3	Q9UM47-1.2	G1738D	Neutral	0.007
NOTCH3	Q9UM47-1.2	G1738E	Neutral	0.031
NOTCH3	Q9UM47-1.2	G1738F	Neutral	0.117
NOTCH3	Q9UM47-1.2	G1738H	Neutral	0.03
NOTCH3	Q9UM47-1.2	G1738I	Neutral	0.386
NOTCH3	Q9UM47-1.2	G1738K	Neutral	0.028
NOTCH3	Q9UM47-1.2	G1738L	Neutral	0.385
NOTCH3	Q9UM47-1.2	G1738M	Neutral	0.121
NOTCH3	Q9UM47-1.2	G1738N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1738P	Neutral	0.033
NOTCH3	Q9UM47-1.2	G1738Q	Neutral	0.03
NOTCH3	Q9UM47-1.2	G1738R	Neutral	0.027
NOTCH3	Q9UM47-1.2	G1738S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1738T	Neutral	0.033
NOTCH3	Q9UM47-1.2	G1738V	Neutral	0.129
NOTCH3	Q9UM47-1.2	G1738W	Neutral	0.025
NOTCH3	Q9UM47-1.2	G1738Y	Neutral	0.114
NOTCH3	Q9UM47-1.2	M1739A	Neutral	0.331
NOTCH3	Q9UM47-1.2	M1739C	Neutral	0.346
NOTCH3	Q9UM47-1.2	M1739D	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	M1739E	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	M1739F	Neutral	0.115
NOTCH3	Q9UM47-1.2	M1739G	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	M1739H	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	M1739I	Neutral	0.029
NOTCH3	Q9UM47-1.2	M1739K	Neutral	0.374
NOTCH3	Q9UM47-1.2	M1739L	Neutral	0.006
NOTCH3	Q9UM47-1.2	M1739N	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	M1739P	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	M1739Q	Neutral	0.116
NOTCH3	Q9UM47-1.2	M1739R	Neutral	0.362
NOTCH3	Q9UM47-1.2	M1739S	Neutral	0.337
NOTCH3	Q9UM47-1.2	M1739T	Neutral	0.354
NOTCH3	Q9UM47-1.2	M1739V	Neutral	0.027
NOTCH3	Q9UM47-1.2	M1739W	Neutral	0.347
NOTCH3	Q9UM47-1.2	M1739Y	Neutral	0.365
NOTCH3	Q9UM47-1.2	G1740A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1740C	Neutral	0.176
NOTCH3	Q9UM47-1.2	G1740D	Neutral	0.01
NOTCH3	Q9UM47-1.2	G1740E	Neutral	0.041
NOTCH3	Q9UM47-1.2	G1740F	Neutral	0.151
NOTCH3	Q9UM47-1.2	G1740H	Neutral	0.039
NOTCH3	Q9UM47-1.2	G1740I	Neutral	0.458
NOTCH3	Q9UM47-1.2	G1740K	Neutral	0.037
NOTCH3	Q9UM47-1.2	G1740L	Neutral	0.457
NOTCH3	Q9UM47-1.2	G1740M	Neutral	0.156
NOTCH3	Q9UM47-1.2	G1740N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1740P	Neutral	0.044
NOTCH3	Q9UM47-1.2	G1740Q	Neutral	0.04
NOTCH3	Q9UM47-1.2	G1740R	Neutral	0.036
NOTCH3	Q9UM47-1.2	G1740S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1740T	Neutral	0.043
NOTCH3	Q9UM47-1.2	G1740V	Neutral	0.166
NOTCH3	Q9UM47-1.2	G1740W	Neutral	0.034
NOTCH3	Q9UM47-1.2	G1740Y	Neutral	0.147
NOTCH3	Q9UM47-1.2	A1741C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1741D	Neutral	0.05
NOTCH3	Q9UM47-1.2	A1741E	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1741F	Neutral	0.042
NOTCH3	Q9UM47-1.2	A1741G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1741H	Neutral	0.045
NOTCH3	Q9UM47-1.2	A1741I	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1741K	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1741L	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1741M	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1741N	Neutral	0.049
NOTCH3	Q9UM47-1.2	A1741P	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1741Q	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1741R	Neutral	0.009
NOTCH3	Q9UM47-1.2	A1741S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1741T	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1741V	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1741W	Neutral	0.154
NOTCH3	Q9UM47-1.2	A1741Y	Neutral	0.041
NOTCH3	Q9UM47-1.2	E1742A	Neutral	0.066
NOTCH3	Q9UM47-1.2	E1742C	Pathogenic	0.878
NOTCH3	Q9UM47-1.2	E1742D	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1742F	Pathogenic	0.612
NOTCH3	Q9UM47-1.2	E1742G	Neutral	0.23
NOTCH3	Q9UM47-1.2	E1742H	Neutral	0.017
NOTCH3	Q9UM47-1.2	E1742I	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	E1742K	Neutral	0.004
NOTCH3	Q9UM47-1.2	E1742L	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	E1742M	Neutral	0.264
NOTCH3	Q9UM47-1.2	E1742N	Neutral	0.017
NOTCH3	Q9UM47-1.2	E1742P	Neutral	0.072
NOTCH3	Q9UM47-1.2	E1742Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1742R	Neutral	0.015
NOTCH3	Q9UM47-1.2	E1742S	Neutral	0.016
NOTCH3	Q9UM47-1.2	E1742T	Neutral	0.072
NOTCH3	Q9UM47-1.2	E1742V	Neutral	0.273
NOTCH3	Q9UM47-1.2	E1742W	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	E1742Y	Neutral	0.251
NOTCH3	Q9UM47-1.2	E1743A	Neutral	0.078
NOTCH3	Q9UM47-1.2	E1743C	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	E1743D	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1743F	Pathogenic	0.652
NOTCH3	Q9UM47-1.2	E1743G	Neutral	0.262
NOTCH3	Q9UM47-1.2	E1743H	Neutral	0.021
NOTCH3	Q9UM47-1.2	E1743I	Pathogenic	0.662
NOTCH3	Q9UM47-1.2	E1743K	Neutral	0.004
NOTCH3	Q9UM47-1.2	E1743L	Pathogenic	0.662
NOTCH3	Q9UM47-1.2	E1743M	Neutral	0.3
NOTCH3	Q9UM47-1.2	E1743N	Neutral	0.02
NOTCH3	Q9UM47-1.2	E1743P	Neutral	0.084
NOTCH3	Q9UM47-1.2	E1743Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	E1743R	Neutral	0.018
NOTCH3	Q9UM47-1.2	E1743S	Neutral	0.018
NOTCH3	Q9UM47-1.2	E1743T	Neutral	0.085
NOTCH3	Q9UM47-1.2	E1743V	Neutral	0.309
NOTCH3	Q9UM47-1.2	E1743W	Pathogenic	0.628
NOTCH3	Q9UM47-1.2	E1743Y	Neutral	0.286
NOTCH3	Q9UM47-1.2	A1744C	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1744D	Neutral	0.076
NOTCH3	Q9UM47-1.2	A1744E	Neutral	0.017
NOTCH3	Q9UM47-1.2	A1744F	Neutral	0.065
NOTCH3	Q9UM47-1.2	A1744G	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1744H	Neutral	0.069
NOTCH3	Q9UM47-1.2	A1744I	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1744K	Neutral	0.015
NOTCH3	Q9UM47-1.2	A1744L	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1744M	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1744N	Neutral	0.075
NOTCH3	Q9UM47-1.2	A1744P	Neutral	0.018
NOTCH3	Q9UM47-1.2	A1744Q	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1744R	Neutral	0.014
NOTCH3	Q9UM47-1.2	A1744S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1744T	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1744V	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1744W	Neutral	0.223
NOTCH3	Q9UM47-1.2	A1744Y	Neutral	0.064
NOTCH3	Q9UM47-1.2	V1745A	Neutral	0.024
NOTCH3	Q9UM47-1.2	V1745C	Neutral	0.106
NOTCH3	Q9UM47-1.2	V1745D	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	V1745E	Neutral	0.367
NOTCH3	Q9UM47-1.2	V1745F	Neutral	0.102
NOTCH3	Q9UM47-1.2	V1745G	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	V1745H	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	V1745I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V1745K	Neutral	0.345
NOTCH3	Q9UM47-1.2	V1745L	Neutral	0.006
NOTCH3	Q9UM47-1.2	V1745M	Neutral	0.006
NOTCH3	Q9UM47-1.2	V1745N	Pathogenic	0.721
NOTCH3	Q9UM47-1.2	V1745P	Neutral	0.355
NOTCH3	Q9UM47-1.2	V1745Q	Neutral	0.362
NOTCH3	Q9UM47-1.2	V1745R	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	V1745S	Neutral	0.341
NOTCH3	Q9UM47-1.2	V1745T	Neutral	0.026
NOTCH3	Q9UM47-1.2	V1745W	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	V1745Y	Neutral	0.1
NOTCH3	Q9UM47-1.2	D1746A	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	D1746C	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	D1746E	Neutral	0.024
NOTCH3	Q9UM47-1.2	D1746F	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	D1746G	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	D1746H	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	D1746I	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	D1746K	Pathogenic	0.675
NOTCH3	Q9UM47-1.2	D1746L	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D1746M	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	D1746N	Neutral	0.104
NOTCH3	Q9UM47-1.2	D1746P	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	D1746Q	Neutral	0.331
NOTCH3	Q9UM47-1.2	D1746R	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	D1746S	Neutral	0.336
NOTCH3	Q9UM47-1.2	D1746T	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	D1746V	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	D1746W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	D1746Y	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	C1747A	Neutral	0.003
NOTCH3	Q9UM47-1.2	C1747D	Neutral	0.218
NOTCH3	Q9UM47-1.2	C1747E	Pathogenic	0.542
NOTCH3	Q9UM47-1.2	C1747F	Neutral	0.049
NOTCH3	Q9UM47-1.2	C1747G	Neutral	0.196
NOTCH3	Q9UM47-1.2	C1747H	Neutral	0.2
NOTCH3	Q9UM47-1.2	C1747I	Neutral	0.012
NOTCH3	Q9UM47-1.2	C1747K	Neutral	0.191
NOTCH3	Q9UM47-1.2	C1747L	Neutral	0.012
NOTCH3	Q9UM47-1.2	C1747M	Neutral	0.012
NOTCH3	Q9UM47-1.2	C1747N	Neutral	0.215
NOTCH3	Q9UM47-1.2	C1747P	Neutral	0.217
NOTCH3	Q9UM47-1.2	C1747Q	Neutral	0.203
NOTCH3	Q9UM47-1.2	C1747R	Neutral	0.183
NOTCH3	Q9UM47-1.2	C1747S	Neutral	0.013
NOTCH3	Q9UM47-1.2	C1747T	Neutral	0.013
NOTCH3	Q9UM47-1.2	C1747V	Neutral	0.012
NOTCH3	Q9UM47-1.2	C1747W	Neutral	0.044
NOTCH3	Q9UM47-1.2	C1747Y	Neutral	0.047
NOTCH3	Q9UM47-1.2	R1748A	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	R1748C	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	R1748D	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	R1748E	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	R1748F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1748G	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	R1748H	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	R1748I	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1748K	Neutral	0.064
NOTCH3	Q9UM47-1.2	R1748L	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	R1748M	Pathogenic	0.863
NOTCH3	Q9UM47-1.2	R1748N	Pathogenic	0.551
NOTCH3	Q9UM47-1.2	R1748P	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	R1748Q	Neutral	0.225
NOTCH3	Q9UM47-1.2	R1748S	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	R1748T	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	R1748V	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1748W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1748Y	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	Q1749A	Neutral	0.347
NOTCH3	Q9UM47-1.2	Q1749C	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	Q1749D	Neutral	0.114
NOTCH3	Q9UM47-1.2	Q1749E	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q1749F	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	Q1749G	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	Q1749H	Neutral	0.121
NOTCH3	Q9UM47-1.2	Q1749I	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	Q1749K	Neutral	0.028
NOTCH3	Q9UM47-1.2	Q1749L	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	Q1749M	Neutral	0.12
NOTCH3	Q9UM47-1.2	Q1749N	Neutral	0.116
NOTCH3	Q9UM47-1.2	Q1749P	Neutral	0.369
NOTCH3	Q9UM47-1.2	Q1749R	Neutral	0.026
NOTCH3	Q9UM47-1.2	Q1749S	Neutral	0.107
NOTCH3	Q9UM47-1.2	Q1749T	Neutral	0.37
NOTCH3	Q9UM47-1.2	Q1749V	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	Q1749W	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	Q1749Y	Neutral	0.366
NOTCH3	Q9UM47-1.2	W1750A	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1750C	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1750D	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1750E	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1750F	Pathogenic	0.867
NOTCH3	Q9UM47-1.2	W1750G	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1750H	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1750I	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1750K	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1750L	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1750M	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	W1750N	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1750P	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1750Q	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1750R	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1750S	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1750T	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1750V	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1750Y	Pathogenic	0.596
NOTCH3	Q9UM47-1.2	T1751A	Neutral	0.399
NOTCH3	Q9UM47-1.2	T1751C	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	T1751D	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	T1751E	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	T1751F	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	T1751G	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	T1751H	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	T1751I	Pathogenic	0.75
NOTCH3	Q9UM47-1.2	T1751K	Pathogenic	0.742
NOTCH3	Q9UM47-1.2	T1751L	Pathogenic	0.75
NOTCH3	Q9UM47-1.2	T1751M	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	T1751N	Neutral	0.422
NOTCH3	Q9UM47-1.2	T1751P	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	T1751Q	Pathogenic	0.756
NOTCH3	Q9UM47-1.2	T1751R	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	T1751S	Neutral	0.13
NOTCH3	Q9UM47-1.2	T1751V	Neutral	0.414
NOTCH3	Q9UM47-1.2	T1751W	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	T1751Y	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	Q1752A	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	Q1752C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	Q1752D	Neutral	0.413
NOTCH3	Q9UM47-1.2	Q1752E	Neutral	0.035
NOTCH3	Q9UM47-1.2	Q1752F	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	Q1752G	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	Q1752H	Neutral	0.431
NOTCH3	Q9UM47-1.2	Q1752I	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	Q1752K	Neutral	0.135
NOTCH3	Q9UM47-1.2	Q1752L	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	Q1752M	Neutral	0.427
NOTCH3	Q9UM47-1.2	Q1752N	Neutral	0.417
NOTCH3	Q9UM47-1.2	Q1752P	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	Q1752R	Neutral	0.129
NOTCH3	Q9UM47-1.2	Q1752S	Neutral	0.396
NOTCH3	Q9UM47-1.2	Q1752T	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	Q1752V	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	Q1752W	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	Q1752Y	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	H1753A	Pathogenic	0.619
NOTCH3	Q9UM47-1.2	H1753C	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	H1753D	Neutral	0.283
NOTCH3	Q9UM47-1.2	H1753E	Neutral	0.085
NOTCH3	Q9UM47-1.2	H1753F	Neutral	0.292
NOTCH3	Q9UM47-1.2	H1753G	Pathogenic	0.602
NOTCH3	Q9UM47-1.2	H1753I	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	H1753K	Neutral	0.291
NOTCH3	Q9UM47-1.2	H1753L	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	H1753M	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	H1753N	Neutral	0.019
NOTCH3	Q9UM47-1.2	H1753P	Pathogenic	0.641
NOTCH3	Q9UM47-1.2	H1753Q	Neutral	0.086
NOTCH3	Q9UM47-1.2	H1753R	Neutral	0.079
NOTCH3	Q9UM47-1.2	H1753S	Neutral	0.268
NOTCH3	Q9UM47-1.2	H1753T	Pathogenic	0.643
NOTCH3	Q9UM47-1.2	H1753V	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	H1753W	Pathogenic	0.629
NOTCH3	Q9UM47-1.2	H1753Y	Neutral	0.004
NOTCH3	Q9UM47-1.2	H1754A	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	H1754C	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1754D	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	H1754E	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	H1754F	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	H1754G	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	H1754I	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1754K	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	H1754L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1754M	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	H1754N	Neutral	0.363
NOTCH3	Q9UM47-1.2	H1754P	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	H1754Q	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	H1754R	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	H1754S	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	H1754T	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	H1754V	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1754W	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	H1754Y	Neutral	0.111
NOTCH3	Q9UM47-1.2	L1755A	Pathogenic	0.572
NOTCH3	Q9UM47-1.2	L1755C	Pathogenic	0.589
NOTCH3	Q9UM47-1.2	L1755D	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	L1755E	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	L1755F	Neutral	0.258
NOTCH3	Q9UM47-1.2	L1755G	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	L1755H	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	L1755I	Neutral	0.017
NOTCH3	Q9UM47-1.2	L1755K	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	L1755M	Neutral	0.017
NOTCH3	Q9UM47-1.2	L1755N	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	L1755P	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	L1755Q	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	L1755R	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	L1755S	Pathogenic	0.862
NOTCH3	Q9UM47-1.2	L1755T	Pathogenic	0.596
NOTCH3	Q9UM47-1.2	L1755V	Neutral	0.069
NOTCH3	Q9UM47-1.2	L1755W	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	L1755Y	Pathogenic	0.608
NOTCH3	Q9UM47-1.2	V1756A	Neutral	0.01
NOTCH3	Q9UM47-1.2	V1756C	Neutral	0.049
NOTCH3	Q9UM47-1.2	V1756D	Pathogenic	0.524
NOTCH3	Q9UM47-1.2	V1756E	Neutral	0.201
NOTCH3	Q9UM47-1.2	V1756F	Neutral	0.047
NOTCH3	Q9UM47-1.2	V1756G	Neutral	0.481
NOTCH3	Q9UM47-1.2	V1756H	Pathogenic	0.524
NOTCH3	Q9UM47-1.2	V1756I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V1756K	Neutral	0.186
NOTCH3	Q9UM47-1.2	V1756L	Neutral	0.002
NOTCH3	Q9UM47-1.2	V1756M	Neutral	0.002
NOTCH3	Q9UM47-1.2	V1756N	Pathogenic	0.529
NOTCH3	Q9UM47-1.2	V1756P	Neutral	0.192
NOTCH3	Q9UM47-1.2	V1756Q	Neutral	0.197
NOTCH3	Q9UM47-1.2	V1756R	Neutral	0.497
NOTCH3	Q9UM47-1.2	V1756S	Neutral	0.183
NOTCH3	Q9UM47-1.2	V1756T	Neutral	0.012
NOTCH3	Q9UM47-1.2	V1756W	Neutral	0.48
NOTCH3	Q9UM47-1.2	V1756Y	Neutral	0.046
NOTCH3	Q9UM47-1.2	A1757C	Neutral	0.349
NOTCH3	Q9UM47-1.2	A1757D	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	A1757E	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	A1757F	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	A1757G	Neutral	0.349
NOTCH3	Q9UM47-1.2	A1757H	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	A1757I	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	A1757K	Pathogenic	0.67
NOTCH3	Q9UM47-1.2	A1757L	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	A1757M	Pathogenic	0.679
NOTCH3	Q9UM47-1.2	A1757N	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	A1757P	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	A1757Q	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	A1757R	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	A1757S	Neutral	0.11
NOTCH3	Q9UM47-1.2	A1757T	Neutral	0.342
NOTCH3	Q9UM47-1.2	A1757V	Neutral	0.333
NOTCH3	Q9UM47-1.2	A1757W	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	A1757Y	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	A1758C	Neutral	0.399
NOTCH3	Q9UM47-1.2	A1758D	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	A1758E	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	A1758F	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	A1758G	Neutral	0.398
NOTCH3	Q9UM47-1.2	A1758H	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	A1758I	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	A1758K	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	A1758L	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	A1758M	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	A1758N	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	A1758P	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	A1758Q	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	A1758R	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	A1758S	Neutral	0.133
NOTCH3	Q9UM47-1.2	A1758T	Neutral	0.391
NOTCH3	Q9UM47-1.2	A1758V	Neutral	0.382
NOTCH3	Q9UM47-1.2	A1758W	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	A1758Y	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	D1759A	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	D1759C	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D1759E	Neutral	0.026
NOTCH3	Q9UM47-1.2	D1759F	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	D1759G	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	D1759H	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	D1759I	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	D1759K	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	D1759L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1759M	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	D1759N	Neutral	0.113
NOTCH3	Q9UM47-1.2	D1759P	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	D1759Q	Neutral	0.352
NOTCH3	Q9UM47-1.2	D1759R	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	D1759S	Neutral	0.357
NOTCH3	Q9UM47-1.2	D1759T	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	D1759V	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D1759W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D1759Y	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	I1760A	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	I1760C	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	I1760D	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	I1760E	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	I1760F	Neutral	0.25
NOTCH3	Q9UM47-1.2	I1760G	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	I1760H	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	I1760K	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	I1760L	Neutral	0.017
NOTCH3	Q9UM47-1.2	I1760M	Neutral	0.071
NOTCH3	Q9UM47-1.2	I1760N	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	I1760P	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	I1760Q	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	I1760R	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	I1760S	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	I1760T	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	I1760V	Neutral	0.003
NOTCH3	Q9UM47-1.2	I1760W	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	I1760Y	Pathogenic	0.599
NOTCH3	Q9UM47-1.2	R1761A	Pathogenic	0.679
NOTCH3	Q9UM47-1.2	R1761C	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	R1761D	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	R1761E	Neutral	0.352
NOTCH3	Q9UM47-1.2	R1761F	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	R1761G	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	R1761H	Neutral	0.361
NOTCH3	Q9UM47-1.2	R1761I	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	R1761K	Neutral	0.028
NOTCH3	Q9UM47-1.2	R1761L	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	R1761M	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	R1761N	Neutral	0.34
NOTCH3	Q9UM47-1.2	R1761P	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	R1761Q	Neutral	0.109
NOTCH3	Q9UM47-1.2	R1761S	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	R1761T	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	R1761V	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	R1761W	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	R1761Y	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	V1762A	Neutral	0.015
NOTCH3	Q9UM47-1.2	V1762C	Neutral	0.068
NOTCH3	Q9UM47-1.2	V1762D	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	V1762E	Neutral	0.264
NOTCH3	Q9UM47-1.2	V1762F	Neutral	0.066
NOTCH3	Q9UM47-1.2	V1762G	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	V1762H	Pathogenic	0.61
NOTCH3	Q9UM47-1.2	V1762I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V1762K	Neutral	0.245
NOTCH3	Q9UM47-1.2	V1762L	Neutral	0.004
NOTCH3	Q9UM47-1.2	V1762M	Neutral	0.004
NOTCH3	Q9UM47-1.2	V1762N	Pathogenic	0.616
NOTCH3	Q9UM47-1.2	V1762P	Neutral	0.254
NOTCH3	Q9UM47-1.2	V1762Q	Neutral	0.26
NOTCH3	Q9UM47-1.2	V1762R	Pathogenic	0.585
NOTCH3	Q9UM47-1.2	V1762S	Neutral	0.243
NOTCH3	Q9UM47-1.2	V1762T	Neutral	0.016
NOTCH3	Q9UM47-1.2	V1762W	Pathogenic	0.568
NOTCH3	Q9UM47-1.2	V1762Y	Neutral	0.064
NOTCH3	Q9UM47-1.2	A1763C	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1763D	Neutral	0.084
NOTCH3	Q9UM47-1.2	A1763E	Neutral	0.018
NOTCH3	Q9UM47-1.2	A1763F	Neutral	0.072
NOTCH3	Q9UM47-1.2	A1763G	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1763H	Neutral	0.076
NOTCH3	Q9UM47-1.2	A1763I	Neutral	0.018
NOTCH3	Q9UM47-1.2	A1763K	Neutral	0.017
NOTCH3	Q9UM47-1.2	A1763L	Neutral	0.018
NOTCH3	Q9UM47-1.2	A1763M	Neutral	0.017
NOTCH3	Q9UM47-1.2	A1763N	Neutral	0.083
NOTCH3	Q9UM47-1.2	A1763P	Neutral	0.02
NOTCH3	Q9UM47-1.2	A1763Q	Neutral	0.018
NOTCH3	Q9UM47-1.2	A1763R	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1763S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1763T	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1763V	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1763W	Neutral	0.242
NOTCH3	Q9UM47-1.2	A1763Y	Neutral	0.07
NOTCH3	Q9UM47-1.2	P1764A	Neutral	0.151
NOTCH3	Q9UM47-1.2	P1764C	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	P1764D	Neutral	0.164
NOTCH3	Q9UM47-1.2	P1764E	Neutral	0.154
NOTCH3	Q9UM47-1.2	P1764F	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	P1764G	Neutral	0.431
NOTCH3	Q9UM47-1.2	P1764H	Neutral	0.444
NOTCH3	Q9UM47-1.2	P1764I	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	P1764K	Neutral	0.142
NOTCH3	Q9UM47-1.2	P1764L	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	P1764M	Neutral	0.438
NOTCH3	Q9UM47-1.2	P1764N	Neutral	0.466
NOTCH3	Q9UM47-1.2	P1764Q	Neutral	0.152
NOTCH3	Q9UM47-1.2	P1764R	Neutral	0.418
NOTCH3	Q9UM47-1.2	P1764S	Neutral	0.155
NOTCH3	Q9UM47-1.2	P1764T	Neutral	0.162
NOTCH3	Q9UM47-1.2	P1764V	Neutral	0.456
NOTCH3	Q9UM47-1.2	P1764W	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	P1764Y	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	A1765C	Neutral	0.022
NOTCH3	Q9UM47-1.2	A1765D	Neutral	0.315
NOTCH3	Q9UM47-1.2	A1765E	Neutral	0.086
NOTCH3	Q9UM47-1.2	A1765F	Neutral	0.28
NOTCH3	Q9UM47-1.2	A1765G	Neutral	0.022
NOTCH3	Q9UM47-1.2	A1765H	Neutral	0.291
NOTCH3	Q9UM47-1.2	A1765I	Neutral	0.082
NOTCH3	Q9UM47-1.2	A1765K	Neutral	0.079
NOTCH3	Q9UM47-1.2	A1765L	Neutral	0.082
NOTCH3	Q9UM47-1.2	A1765M	Neutral	0.081
NOTCH3	Q9UM47-1.2	A1765N	Neutral	0.31
NOTCH3	Q9UM47-1.2	A1765P	Neutral	0.091
NOTCH3	Q9UM47-1.2	A1765Q	Neutral	0.084
NOTCH3	Q9UM47-1.2	A1765R	Neutral	0.075
NOTCH3	Q9UM47-1.2	A1765S	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1765T	Neutral	0.021
NOTCH3	Q9UM47-1.2	A1765V	Neutral	0.021
NOTCH3	Q9UM47-1.2	A1765W	Pathogenic	0.614
NOTCH3	Q9UM47-1.2	A1765Y	Neutral	0.274
NOTCH3	Q9UM47-1.2	M1766A	Pathogenic	0.646
NOTCH3	Q9UM47-1.2	M1766C	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	M1766D	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	M1766E	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	M1766F	Neutral	0.323
NOTCH3	Q9UM47-1.2	M1766G	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	M1766H	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	M1766I	Neutral	0.098
NOTCH3	Q9UM47-1.2	M1766K	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	M1766L	Neutral	0.023
NOTCH3	Q9UM47-1.2	M1766N	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	M1766P	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	M1766Q	Neutral	0.325
NOTCH3	Q9UM47-1.2	M1766R	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	M1766S	Pathogenic	0.652
NOTCH3	Q9UM47-1.2	M1766T	Pathogenic	0.668
NOTCH3	Q9UM47-1.2	M1766V	Neutral	0.092
NOTCH3	Q9UM47-1.2	M1766W	Pathogenic	0.662
NOTCH3	Q9UM47-1.2	M1766Y	Pathogenic	0.679
NOTCH3	Q9UM47-1.2	A1767C	Neutral	0.187
NOTCH3	Q9UM47-1.2	A1767D	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	A1767E	Neutral	0.49
NOTCH3	Q9UM47-1.2	A1767F	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	A1767G	Neutral	0.187
NOTCH3	Q9UM47-1.2	A1767H	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	A1767I	Neutral	0.477
NOTCH3	Q9UM47-1.2	A1767K	Neutral	0.466
NOTCH3	Q9UM47-1.2	A1767L	Neutral	0.477
NOTCH3	Q9UM47-1.2	A1767M	Neutral	0.476
NOTCH3	Q9UM47-1.2	A1767N	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	A1767P	Pathogenic	0.507
NOTCH3	Q9UM47-1.2	A1767Q	Neutral	0.484
NOTCH3	Q9UM47-1.2	A1767R	Neutral	0.453
NOTCH3	Q9UM47-1.2	A1767S	Neutral	0.05
NOTCH3	Q9UM47-1.2	A1767T	Neutral	0.182
NOTCH3	Q9UM47-1.2	A1767V	Neutral	0.177
NOTCH3	Q9UM47-1.2	A1767W	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	A1767Y	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	L1768A	Neutral	0.26
NOTCH3	Q9UM47-1.2	L1768C	Neutral	0.273
NOTCH3	Q9UM47-1.2	L1768D	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	L1768E	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	L1768F	Neutral	0.084
NOTCH3	Q9UM47-1.2	L1768G	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	L1768H	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	L1768I	Neutral	0.005
NOTCH3	Q9UM47-1.2	L1768K	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	L1768M	Neutral	0.005
NOTCH3	Q9UM47-1.2	L1768N	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	L1768P	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	L1768Q	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	L1768R	Pathogenic	0.647
NOTCH3	Q9UM47-1.2	L1768S	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	L1768T	Neutral	0.28
NOTCH3	Q9UM47-1.2	L1768V	Neutral	0.019
NOTCH3	Q9UM47-1.2	L1768W	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	L1768Y	Neutral	0.29
NOTCH3	Q9UM47-1.2	T1769A	Neutral	0.463
NOTCH3	Q9UM47-1.2	T1769C	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	T1769D	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	T1769E	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	T1769F	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	T1769G	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	T1769H	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	T1769I	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	T1769K	Pathogenic	0.788
NOTCH3	Q9UM47-1.2	T1769L	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	T1769M	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	T1769N	Neutral	0.486
NOTCH3	Q9UM47-1.2	T1769P	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	T1769Q	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	T1769R	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	T1769S	Neutral	0.162
NOTCH3	Q9UM47-1.2	T1769V	Neutral	0.478
NOTCH3	Q9UM47-1.2	T1769W	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	T1769Y	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	P1770A	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	P1770C	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	P1770D	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	P1770E	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	P1770F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P1770G	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	P1770H	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	P1770I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P1770K	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	P1770L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P1770M	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	P1770N	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	P1770Q	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	P1770R	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	P1770S	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	P1770T	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	P1770V	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	P1770W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P1770Y	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	P1771A	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	P1771C	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	P1771D	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	P1771E	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	P1771F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P1771G	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	P1771H	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	P1771I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P1771K	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	P1771L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P1771M	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	P1771N	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	P1771Q	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	P1771R	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	P1771S	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	P1771T	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	P1771V	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	P1771W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P1771Y	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	Q1772A	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	Q1772C	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	Q1772D	Neutral	0.373
NOTCH3	Q9UM47-1.2	Q1772E	Neutral	0.03
NOTCH3	Q9UM47-1.2	Q1772F	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	Q1772G	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	Q1772H	Neutral	0.39
NOTCH3	Q9UM47-1.2	Q1772I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	Q1772K	Neutral	0.117
NOTCH3	Q9UM47-1.2	Q1772L	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	Q1772M	Neutral	0.387
NOTCH3	Q9UM47-1.2	Q1772N	Neutral	0.377
NOTCH3	Q9UM47-1.2	Q1772P	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	Q1772R	Neutral	0.112
NOTCH3	Q9UM47-1.2	Q1772S	Neutral	0.356
NOTCH3	Q9UM47-1.2	Q1772T	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	Q1772V	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	Q1772W	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	Q1772Y	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	G1773A	Neutral	0.036
NOTCH3	Q9UM47-1.2	G1773C	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	G1773D	Neutral	0.134
NOTCH3	Q9UM47-1.2	G1773E	Neutral	0.396
NOTCH3	Q9UM47-1.2	G1773F	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	G1773H	Neutral	0.387
NOTCH3	Q9UM47-1.2	G1773I	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	G1773K	Neutral	0.373
NOTCH3	Q9UM47-1.2	G1773L	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	G1773M	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	G1773N	Neutral	0.032
NOTCH3	Q9UM47-1.2	G1773P	Neutral	0.414
NOTCH3	Q9UM47-1.2	G1773Q	Neutral	0.391
NOTCH3	Q9UM47-1.2	G1773R	Neutral	0.361
NOTCH3	Q9UM47-1.2	G1773S	Neutral	0.035
NOTCH3	Q9UM47-1.2	G1773T	Neutral	0.41
NOTCH3	Q9UM47-1.2	G1773V	Pathogenic	0.753
NOTCH3	Q9UM47-1.2	G1773W	Neutral	0.35
NOTCH3	Q9UM47-1.2	G1773Y	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	D1774A	Neutral	0.374
NOTCH3	Q9UM47-1.2	D1774C	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	D1774E	Neutral	0.001
NOTCH3	Q9UM47-1.2	D1774F	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	D1774G	Neutral	0.108
NOTCH3	Q9UM47-1.2	D1774H	Neutral	0.115
NOTCH3	Q9UM47-1.2	D1774I	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	D1774K	Neutral	0.108
NOTCH3	Q9UM47-1.2	D1774L	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	D1774M	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	D1774N	Neutral	0.007
NOTCH3	Q9UM47-1.2	D1774P	Neutral	0.126
NOTCH3	Q9UM47-1.2	D1774Q	Neutral	0.028
NOTCH3	Q9UM47-1.2	D1774R	Neutral	0.343
NOTCH3	Q9UM47-1.2	D1774S	Neutral	0.029
NOTCH3	Q9UM47-1.2	D1774T	Neutral	0.125
NOTCH3	Q9UM47-1.2	D1774V	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	D1774W	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	D1774Y	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	A1775C	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1775D	Neutral	0.046
NOTCH3	Q9UM47-1.2	A1775E	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1775F	Neutral	0.039
NOTCH3	Q9UM47-1.2	A1775G	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1775H	Neutral	0.041
NOTCH3	Q9UM47-1.2	A1775I	Neutral	0.009
NOTCH3	Q9UM47-1.2	A1775K	Neutral	0.009
NOTCH3	Q9UM47-1.2	A1775L	Neutral	0.009
NOTCH3	Q9UM47-1.2	A1775M	Neutral	0.009
NOTCH3	Q9UM47-1.2	A1775N	Neutral	0.045
NOTCH3	Q9UM47-1.2	A1775P	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1775Q	Neutral	0.01
NOTCH3	Q9UM47-1.2	A1775R	Neutral	0.008
NOTCH3	Q9UM47-1.2	A1775S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1775T	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1775V	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1775W	Neutral	0.143
NOTCH3	Q9UM47-1.2	A1775Y	Neutral	0.038
NOTCH3	Q9UM47-1.2	D1776A	Pathogenic	0.546
NOTCH3	Q9UM47-1.2	D1776C	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	D1776E	Neutral	0.003
NOTCH3	Q9UM47-1.2	D1776F	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	D1776G	Neutral	0.197
NOTCH3	Q9UM47-1.2	D1776H	Neutral	0.207
NOTCH3	Q9UM47-1.2	D1776I	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	D1776K	Neutral	0.195
NOTCH3	Q9UM47-1.2	D1776L	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	D1776M	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	D1776N	Neutral	0.013
NOTCH3	Q9UM47-1.2	D1776P	Neutral	0.225
NOTCH3	Q9UM47-1.2	D1776Q	Neutral	0.055
NOTCH3	Q9UM47-1.2	D1776R	Pathogenic	0.512
NOTCH3	Q9UM47-1.2	D1776S	Neutral	0.056
NOTCH3	Q9UM47-1.2	D1776T	Neutral	0.223
NOTCH3	Q9UM47-1.2	D1776V	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	D1776W	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	D1776Y	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	A1777C	Neutral	0.017
NOTCH3	Q9UM47-1.2	A1777D	Neutral	0.257
NOTCH3	Q9UM47-1.2	A1777E	Neutral	0.066
NOTCH3	Q9UM47-1.2	A1777F	Neutral	0.227
NOTCH3	Q9UM47-1.2	A1777G	Neutral	0.017
NOTCH3	Q9UM47-1.2	A1777H	Neutral	0.236
NOTCH3	Q9UM47-1.2	A1777I	Neutral	0.063
NOTCH3	Q9UM47-1.2	A1777K	Neutral	0.06
NOTCH3	Q9UM47-1.2	A1777L	Neutral	0.063
NOTCH3	Q9UM47-1.2	A1777M	Neutral	0.063
NOTCH3	Q9UM47-1.2	A1777N	Neutral	0.253
NOTCH3	Q9UM47-1.2	A1777P	Neutral	0.071
NOTCH3	Q9UM47-1.2	A1777Q	Neutral	0.065
NOTCH3	Q9UM47-1.2	A1777R	Neutral	0.058
NOTCH3	Q9UM47-1.2	A1777S	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1777T	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1777V	Neutral	0.016
NOTCH3	Q9UM47-1.2	A1777W	Pathogenic	0.546
NOTCH3	Q9UM47-1.2	A1777Y	Neutral	0.221
NOTCH3	Q9UM47-1.2	D1778A	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	D1778C	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	D1778E	Neutral	0.016
NOTCH3	Q9UM47-1.2	D1778F	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	D1778G	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	D1778H	Pathogenic	0.602
NOTCH3	Q9UM47-1.2	D1778I	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	D1778K	Pathogenic	0.585
NOTCH3	Q9UM47-1.2	D1778L	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	D1778M	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	D1778N	Neutral	0.073
NOTCH3	Q9UM47-1.2	D1778P	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	D1778Q	Neutral	0.252
NOTCH3	Q9UM47-1.2	D1778R	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	D1778S	Neutral	0.256
NOTCH3	Q9UM47-1.2	D1778T	Pathogenic	0.625
NOTCH3	Q9UM47-1.2	D1778V	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	D1778W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	D1778Y	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	G1779A	Neutral	0.004
NOTCH3	Q9UM47-1.2	G1779C	Neutral	0.26
NOTCH3	Q9UM47-1.2	G1779D	Neutral	0.016
NOTCH3	Q9UM47-1.2	G1779E	Neutral	0.066
NOTCH3	Q9UM47-1.2	G1779F	Neutral	0.226
NOTCH3	Q9UM47-1.2	G1779H	Neutral	0.063
NOTCH3	Q9UM47-1.2	G1779I	Pathogenic	0.581
NOTCH3	Q9UM47-1.2	G1779K	Neutral	0.06
NOTCH3	Q9UM47-1.2	G1779L	Pathogenic	0.581
NOTCH3	Q9UM47-1.2	G1779M	Neutral	0.233
NOTCH3	Q9UM47-1.2	G1779N	Neutral	0.004
NOTCH3	Q9UM47-1.2	G1779P	Neutral	0.07
NOTCH3	Q9UM47-1.2	G1779Q	Neutral	0.064
NOTCH3	Q9UM47-1.2	G1779R	Neutral	0.057
NOTCH3	Q9UM47-1.2	G1779S	Neutral	0.004
NOTCH3	Q9UM47-1.2	G1779T	Neutral	0.069
NOTCH3	Q9UM47-1.2	G1779V	Neutral	0.246
NOTCH3	Q9UM47-1.2	G1779W	Neutral	0.055
NOTCH3	Q9UM47-1.2	G1779Y	Neutral	0.221
NOTCH3	Q9UM47-1.2	M1780A	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	M1780C	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	M1780D	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	M1780E	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	M1780F	Neutral	0.424
NOTCH3	Q9UM47-1.2	M1780G	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	M1780H	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	M1780I	Neutral	0.144
NOTCH3	Q9UM47-1.2	M1780K	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	M1780L	Neutral	0.036
NOTCH3	Q9UM47-1.2	M1780N	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	M1780P	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	M1780Q	Neutral	0.427
NOTCH3	Q9UM47-1.2	M1780R	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	M1780S	Pathogenic	0.743
NOTCH3	Q9UM47-1.2	M1780T	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	M1780V	Neutral	0.135
NOTCH3	Q9UM47-1.2	M1780W	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	M1780Y	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	D1781A	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	D1781C	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1781E	Neutral	0.029
NOTCH3	Q9UM47-1.2	D1781F	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	D1781G	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	D1781H	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	D1781I	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D1781K	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	D1781L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1781M	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D1781N	Neutral	0.123
NOTCH3	Q9UM47-1.2	D1781P	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	D1781Q	Neutral	0.374
NOTCH3	Q9UM47-1.2	D1781R	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	D1781S	Neutral	0.379
NOTCH3	Q9UM47-1.2	D1781T	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	D1781V	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D1781W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D1781Y	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	V1782A	Pathogenic	0.511
NOTCH3	Q9UM47-1.2	V1782C	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	V1782D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	V1782E	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	V1782F	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	V1782G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	V1782H	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	V1782I	Neutral	0.012
NOTCH3	Q9UM47-1.2	V1782K	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	V1782L	Neutral	0.198
NOTCH3	Q9UM47-1.2	V1782M	Neutral	0.197
NOTCH3	Q9UM47-1.2	V1782N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	V1782P	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	V1782Q	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	V1782R	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	V1782S	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	V1782T	Pathogenic	0.536
NOTCH3	Q9UM47-1.2	V1782W	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	V1782Y	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	N1783A	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	N1783C	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	N1783D	Neutral	0.101
NOTCH3	Q9UM47-1.2	N1783E	Neutral	0.332
NOTCH3	Q9UM47-1.2	N1783F	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	N1783G	Neutral	0.303
NOTCH3	Q9UM47-1.2	N1783H	Neutral	0.096
NOTCH3	Q9UM47-1.2	N1783I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	N1783K	Neutral	0.31
NOTCH3	Q9UM47-1.2	N1783L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	N1783M	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	N1783P	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	N1783Q	Neutral	0.328
NOTCH3	Q9UM47-1.2	N1783R	Neutral	0.3
NOTCH3	Q9UM47-1.2	N1783S	Neutral	0.095
NOTCH3	Q9UM47-1.2	N1783T	Neutral	0.342
NOTCH3	Q9UM47-1.2	N1783V	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	N1783W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	N1783Y	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	V1784A	Neutral	0.448
NOTCH3	Q9UM47-1.2	V1784C	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	V1784D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	V1784E	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	V1784F	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	V1784G	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	V1784H	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	V1784I	Neutral	0.009
NOTCH3	Q9UM47-1.2	V1784K	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	V1784L	Neutral	0.16
NOTCH3	Q9UM47-1.2	V1784M	Neutral	0.16
NOTCH3	Q9UM47-1.2	V1784N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	V1784P	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	V1784Q	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	V1784R	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	V1784S	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	V1784T	Neutral	0.473
NOTCH3	Q9UM47-1.2	V1784W	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	V1784Y	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	R1785A	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	R1785C	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	R1785D	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	R1785E	Neutral	0.46
NOTCH3	Q9UM47-1.2	R1785F	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	R1785G	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	R1785H	Neutral	0.471
NOTCH3	Q9UM47-1.2	R1785I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	R1785K	Neutral	0.043
NOTCH3	Q9UM47-1.2	R1785L	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	R1785M	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	R1785N	Neutral	0.448
NOTCH3	Q9UM47-1.2	R1785P	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	R1785Q	Neutral	0.161
NOTCH3	Q9UM47-1.2	R1785S	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	R1785T	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	R1785V	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	R1785W	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	R1785Y	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	G1786A	Neutral	0.235
NOTCH3	Q9UM47-1.2	G1786C	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G1786D	Pathogenic	0.561
NOTCH3	Q9UM47-1.2	G1786E	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	G1786F	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G1786H	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	G1786I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1786K	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	G1786L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1786M	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1786N	Neutral	0.216
NOTCH3	Q9UM47-1.2	G1786P	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	G1786Q	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	G1786R	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G1786S	Neutral	0.23
NOTCH3	Q9UM47-1.2	G1786T	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	G1786V	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	G1786W	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	G1786Y	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	P1787A	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	P1787C	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	P1787D	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	P1787E	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	P1787F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P1787G	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	P1787H	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	P1787I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P1787K	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	P1787L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P1787M	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	P1787N	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	P1787Q	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	P1787R	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	P1787S	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	P1787T	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	P1787V	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	P1787W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P1787Y	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	D1788A	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	D1788C	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	D1788E	Neutral	0.016
NOTCH3	Q9UM47-1.2	D1788F	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	D1788G	Pathogenic	0.589
NOTCH3	Q9UM47-1.2	D1788H	Pathogenic	0.604
NOTCH3	Q9UM47-1.2	D1788I	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	D1788K	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	D1788L	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	D1788M	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	D1788N	Neutral	0.074
NOTCH3	Q9UM47-1.2	D1788P	Pathogenic	0.629
NOTCH3	Q9UM47-1.2	D1788Q	Neutral	0.253
NOTCH3	Q9UM47-1.2	D1788R	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	D1788S	Neutral	0.257
NOTCH3	Q9UM47-1.2	D1788T	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	D1788V	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	D1788W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	D1788Y	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	G1789A	Neutral	0.223
NOTCH3	Q9UM47-1.2	G1789C	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	G1789D	Pathogenic	0.545
NOTCH3	Q9UM47-1.2	G1789E	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G1789F	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	G1789H	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	G1789I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1789K	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	G1789L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1789M	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G1789N	Neutral	0.205
NOTCH3	Q9UM47-1.2	G1789P	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	G1789Q	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	G1789R	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	G1789S	Neutral	0.219
NOTCH3	Q9UM47-1.2	G1789T	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	G1789V	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1789W	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	G1789Y	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	F1790A	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	F1790C	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	F1790D	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	F1790E	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	F1790G	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	F1790H	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	F1790I	Neutral	0.381
NOTCH3	Q9UM47-1.2	F1790K	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	F1790L	Neutral	0.381
NOTCH3	Q9UM47-1.2	F1790M	Neutral	0.382
NOTCH3	Q9UM47-1.2	F1790N	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	F1790P	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F1790Q	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	F1790R	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	F1790S	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	F1790T	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	F1790V	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	F1790W	Neutral	0.113
NOTCH3	Q9UM47-1.2	F1790Y	Neutral	0.007
NOTCH3	Q9UM47-1.2	T1791A	Neutral	0.442
NOTCH3	Q9UM47-1.2	T1791C	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	T1791D	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	T1791E	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	T1791F	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	T1791G	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	T1791H	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	T1791I	Pathogenic	0.782
NOTCH3	Q9UM47-1.2	T1791K	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	T1791L	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	T1791M	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	T1791N	Neutral	0.465
NOTCH3	Q9UM47-1.2	T1791P	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	T1791Q	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	T1791R	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	T1791S	Neutral	0.151
NOTCH3	Q9UM47-1.2	T1791V	Neutral	0.457
NOTCH3	Q9UM47-1.2	T1791W	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	T1791Y	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	P1792A	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	P1792C	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	P1792D	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	P1792E	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	P1792F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P1792G	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	P1792H	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	P1792I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P1792K	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	P1792L	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	P1792M	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	P1792N	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	P1792Q	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	P1792R	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	P1792S	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	P1792T	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	P1792V	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	P1792W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P1792Y	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	L1793A	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	L1793C	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	L1793D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1793E	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L1793F	Neutral	0.359
NOTCH3	Q9UM47-1.2	L1793G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1793H	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1793I	Neutral	0.027
NOTCH3	Q9UM47-1.2	L1793K	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	L1793M	Neutral	0.027
NOTCH3	Q9UM47-1.2	L1793N	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L1793P	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	L1793Q	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	L1793R	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	L1793S	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	L1793T	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	L1793V	Neutral	0.107
NOTCH3	Q9UM47-1.2	L1793W	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	L1793Y	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	M1794A	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	M1794C	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	M1794D	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	M1794E	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	M1794F	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	M1794G	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	M1794H	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	M1794I	Pathogenic	0.649
NOTCH3	Q9UM47-1.2	M1794K	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	M1794L	Neutral	0.289
NOTCH3	Q9UM47-1.2	M1794N	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	M1794P	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	M1794Q	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	M1794R	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	M1794S	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	M1794T	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	M1794V	Pathogenic	0.631
NOTCH3	Q9UM47-1.2	M1794W	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	M1794Y	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	L1795A	Neutral	0.228
NOTCH3	Q9UM47-1.2	L1795C	Neutral	0.24
NOTCH3	Q9UM47-1.2	L1795D	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	L1795E	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	L1795F	Neutral	0.071
NOTCH3	Q9UM47-1.2	L1795G	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	L1795H	Pathogenic	0.882
NOTCH3	Q9UM47-1.2	L1795I	Neutral	0.004
NOTCH3	Q9UM47-1.2	L1795K	Pathogenic	0.619
NOTCH3	Q9UM47-1.2	L1795M	Neutral	0.004
NOTCH3	Q9UM47-1.2	L1795N	Pathogenic	0.873
NOTCH3	Q9UM47-1.2	L1795P	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	L1795Q	Pathogenic	0.618
NOTCH3	Q9UM47-1.2	L1795R	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	L1795S	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	L1795T	Neutral	0.246
NOTCH3	Q9UM47-1.2	L1795V	Neutral	0.016
NOTCH3	Q9UM47-1.2	L1795W	Pathogenic	0.589
NOTCH3	Q9UM47-1.2	L1795Y	Neutral	0.255
NOTCH3	Q9UM47-1.2	A1796C	Neutral	0.375
NOTCH3	Q9UM47-1.2	A1796D	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	A1796E	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	A1796F	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	A1796G	Neutral	0.374
NOTCH3	Q9UM47-1.2	A1796H	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	A1796I	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	A1796K	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	A1796L	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	A1796M	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	A1796N	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	A1796P	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	A1796Q	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	A1796R	Pathogenic	0.684
NOTCH3	Q9UM47-1.2	A1796S	Neutral	0.121
NOTCH3	Q9UM47-1.2	A1796T	Neutral	0.367
NOTCH3	Q9UM47-1.2	A1796V	Neutral	0.358
NOTCH3	Q9UM47-1.2	A1796W	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	A1796Y	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	S1797A	Neutral	0.068
NOTCH3	Q9UM47-1.2	S1797C	Pathogenic	0.596
NOTCH3	Q9UM47-1.2	S1797D	Neutral	0.241
NOTCH3	Q9UM47-1.2	S1797E	Neutral	0.228
NOTCH3	Q9UM47-1.2	S1797F	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	S1797G	Neutral	0.235
NOTCH3	Q9UM47-1.2	S1797H	Pathogenic	0.565
NOTCH3	Q9UM47-1.2	S1797I	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	S1797K	Neutral	0.212
NOTCH3	Q9UM47-1.2	S1797L	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	S1797M	Pathogenic	0.561
NOTCH3	Q9UM47-1.2	S1797N	Neutral	0.064
NOTCH3	Q9UM47-1.2	S1797P	Pathogenic	0.592
NOTCH3	Q9UM47-1.2	S1797Q	Neutral	0.224
NOTCH3	Q9UM47-1.2	S1797R	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	S1797T	Neutral	0.065
NOTCH3	Q9UM47-1.2	S1797V	Pathogenic	0.862
NOTCH3	Q9UM47-1.2	S1797W	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	S1797Y	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	F1798A	Neutral	0.498
NOTCH3	Q9UM47-1.2	F1798C	Pathogenic	0.515
NOTCH3	Q9UM47-1.2	F1798D	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	F1798E	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	F1798G	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	F1798H	Neutral	0.21
NOTCH3	Q9UM47-1.2	F1798I	Neutral	0.056
NOTCH3	Q9UM47-1.2	F1798K	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	F1798L	Neutral	0.056
NOTCH3	Q9UM47-1.2	F1798M	Neutral	0.056
NOTCH3	Q9UM47-1.2	F1798N	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	F1798P	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	F1798Q	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	F1798R	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	F1798S	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	F1798T	Pathogenic	0.523
NOTCH3	Q9UM47-1.2	F1798V	Neutral	0.2
NOTCH3	Q9UM47-1.2	F1798W	Neutral	0.012
NOTCH3	Q9UM47-1.2	F1798Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	C1799A	Neutral	0.006
NOTCH3	Q9UM47-1.2	C1799D	Neutral	0.384
NOTCH3	Q9UM47-1.2	C1799E	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	C1799F	Neutral	0.103
NOTCH3	Q9UM47-1.2	C1799G	Neutral	0.353
NOTCH3	Q9UM47-1.2	C1799H	Neutral	0.358
NOTCH3	Q9UM47-1.2	C1799I	Neutral	0.026
NOTCH3	Q9UM47-1.2	C1799K	Neutral	0.345
NOTCH3	Q9UM47-1.2	C1799L	Neutral	0.026
NOTCH3	Q9UM47-1.2	C1799M	Neutral	0.025
NOTCH3	Q9UM47-1.2	C1799N	Neutral	0.379
NOTCH3	Q9UM47-1.2	C1799P	Neutral	0.382
NOTCH3	Q9UM47-1.2	C1799Q	Neutral	0.362
NOTCH3	Q9UM47-1.2	C1799R	Neutral	0.334
NOTCH3	Q9UM47-1.2	C1799S	Neutral	0.028
NOTCH3	Q9UM47-1.2	C1799T	Neutral	0.029
NOTCH3	Q9UM47-1.2	C1799V	Neutral	0.027
NOTCH3	Q9UM47-1.2	C1799W	Neutral	0.094
NOTCH3	Q9UM47-1.2	C1799Y	Neutral	0.1
NOTCH3	Q9UM47-1.2	G1800A	Neutral	0.105
NOTCH3	Q9UM47-1.2	G1800C	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	G1800D	Neutral	0.327
NOTCH3	Q9UM47-1.2	G1800E	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	G1800F	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	G1800H	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	G1800I	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	G1800K	Pathogenic	0.652
NOTCH3	Q9UM47-1.2	G1800L	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	G1800M	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	G1800N	Neutral	0.095
NOTCH3	Q9UM47-1.2	G1800P	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	G1800Q	Pathogenic	0.669
NOTCH3	Q9UM47-1.2	G1800R	Pathogenic	0.64
NOTCH3	Q9UM47-1.2	G1800S	Neutral	0.102
NOTCH3	Q9UM47-1.2	G1800T	Pathogenic	0.686
NOTCH3	Q9UM47-1.2	G1800V	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	G1800W	Pathogenic	0.629
NOTCH3	Q9UM47-1.2	G1800Y	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	G1801A	Neutral	0.198
NOTCH3	Q9UM47-1.2	G1801C	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G1801D	Pathogenic	0.507
NOTCH3	Q9UM47-1.2	G1801E	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	G1801F	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	G1801H	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	G1801I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G1801K	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	G1801L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G1801M	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	G1801N	Neutral	0.181
NOTCH3	Q9UM47-1.2	G1801P	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	G1801Q	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	G1801R	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	G1801S	Neutral	0.194
NOTCH3	Q9UM47-1.2	G1801T	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	G1801V	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	G1801W	Pathogenic	0.782
NOTCH3	Q9UM47-1.2	G1801Y	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	A1802C	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1802D	Neutral	0.122
NOTCH3	Q9UM47-1.2	A1802E	Neutral	0.028
NOTCH3	Q9UM47-1.2	A1802F	Neutral	0.106
NOTCH3	Q9UM47-1.2	A1802G	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1802H	Neutral	0.111
NOTCH3	Q9UM47-1.2	A1802I	Neutral	0.026
NOTCH3	Q9UM47-1.2	A1802K	Neutral	0.025
NOTCH3	Q9UM47-1.2	A1802L	Neutral	0.026
NOTCH3	Q9UM47-1.2	A1802M	Neutral	0.026
NOTCH3	Q9UM47-1.2	A1802N	Neutral	0.12
NOTCH3	Q9UM47-1.2	A1802P	Neutral	0.03
NOTCH3	Q9UM47-1.2	A1802Q	Neutral	0.027
NOTCH3	Q9UM47-1.2	A1802R	Neutral	0.024
NOTCH3	Q9UM47-1.2	A1802S	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1802T	Neutral	0.007
NOTCH3	Q9UM47-1.2	A1802V	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1802W	Neutral	0.326
NOTCH3	Q9UM47-1.2	A1802Y	Neutral	0.103
NOTCH3	Q9UM47-1.2	L1803A	Neutral	0.209
NOTCH3	Q9UM47-1.2	L1803C	Neutral	0.22
NOTCH3	Q9UM47-1.2	L1803D	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	L1803E	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	L1803F	Neutral	0.064
NOTCH3	Q9UM47-1.2	L1803G	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	L1803H	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	L1803I	Neutral	0.003
NOTCH3	Q9UM47-1.2	L1803K	Pathogenic	0.592
NOTCH3	Q9UM47-1.2	L1803M	Neutral	0.003
NOTCH3	Q9UM47-1.2	L1803N	Pathogenic	0.861
NOTCH3	Q9UM47-1.2	L1803P	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	L1803Q	Pathogenic	0.592
NOTCH3	Q9UM47-1.2	L1803R	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	L1803S	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	L1803T	Neutral	0.226
NOTCH3	Q9UM47-1.2	L1803V	Neutral	0.014
NOTCH3	Q9UM47-1.2	L1803W	Pathogenic	0.562
NOTCH3	Q9UM47-1.2	L1803Y	Neutral	0.235
NOTCH3	Q9UM47-1.2	E1804A	Neutral	0.388
NOTCH3	Q9UM47-1.2	E1804C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	E1804D	Neutral	0.007
NOTCH3	Q9UM47-1.2	E1804F	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	E1804G	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	E1804H	Neutral	0.136
NOTCH3	Q9UM47-1.2	E1804I	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	E1804K	Neutral	0.031
NOTCH3	Q9UM47-1.2	E1804L	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	E1804M	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	E1804N	Neutral	0.134
NOTCH3	Q9UM47-1.2	E1804P	Neutral	0.41
NOTCH3	Q9UM47-1.2	E1804Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	E1804R	Neutral	0.123
NOTCH3	Q9UM47-1.2	E1804S	Neutral	0.124
NOTCH3	Q9UM47-1.2	E1804T	Neutral	0.412
NOTCH3	Q9UM47-1.2	E1804V	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	E1804W	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	E1804Y	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	P1805A	Neutral	0.029
NOTCH3	Q9UM47-1.2	P1805C	Neutral	0.402
NOTCH3	Q9UM47-1.2	P1805D	Neutral	0.032
NOTCH3	Q9UM47-1.2	P1805E	Neutral	0.03
NOTCH3	Q9UM47-1.2	P1805F	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	P1805G	Neutral	0.114
NOTCH3	Q9UM47-1.2	P1805H	Neutral	0.119
NOTCH3	Q9UM47-1.2	P1805I	Neutral	0.376
NOTCH3	Q9UM47-1.2	P1805K	Neutral	0.027
NOTCH3	Q9UM47-1.2	P1805L	Neutral	0.376
NOTCH3	Q9UM47-1.2	P1805M	Neutral	0.117
NOTCH3	Q9UM47-1.2	P1805N	Neutral	0.129
NOTCH3	Q9UM47-1.2	P1805Q	Neutral	0.029
NOTCH3	Q9UM47-1.2	P1805R	Neutral	0.108
NOTCH3	Q9UM47-1.2	P1805S	Neutral	0.03
NOTCH3	Q9UM47-1.2	P1805T	Neutral	0.032
NOTCH3	Q9UM47-1.2	P1805V	Neutral	0.124
NOTCH3	Q9UM47-1.2	P1805W	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	P1805Y	Neutral	0.36
NOTCH3	Q9UM47-1.2	M1806A	Neutral	0.2
NOTCH3	Q9UM47-1.2	M1806C	Neutral	0.212
NOTCH3	Q9UM47-1.2	M1806D	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	M1806E	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	M1806F	Neutral	0.062
NOTCH3	Q9UM47-1.2	M1806G	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	M1806H	Pathogenic	0.582
NOTCH3	Q9UM47-1.2	M1806I	Neutral	0.015
NOTCH3	Q9UM47-1.2	M1806K	Neutral	0.232
NOTCH3	Q9UM47-1.2	M1806L	Neutral	0.003
NOTCH3	Q9UM47-1.2	M1806N	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	M1806P	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	M1806Q	Neutral	0.062
NOTCH3	Q9UM47-1.2	M1806R	Neutral	0.224
NOTCH3	Q9UM47-1.2	M1806S	Neutral	0.205
NOTCH3	Q9UM47-1.2	M1806T	Neutral	0.217
NOTCH3	Q9UM47-1.2	M1806V	Neutral	0.014
NOTCH3	Q9UM47-1.2	M1806W	Neutral	0.212
NOTCH3	Q9UM47-1.2	M1806Y	Neutral	0.225
NOTCH3	Q9UM47-1.2	P1807A	Neutral	0.015
NOTCH3	Q9UM47-1.2	P1807C	Neutral	0.253
NOTCH3	Q9UM47-1.2	P1807D	Neutral	0.016
NOTCH3	Q9UM47-1.2	P1807E	Neutral	0.015
NOTCH3	Q9UM47-1.2	P1807F	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	P1807G	Neutral	0.061
NOTCH3	Q9UM47-1.2	P1807H	Neutral	0.064
NOTCH3	Q9UM47-1.2	P1807I	Neutral	0.233
NOTCH3	Q9UM47-1.2	P1807K	Neutral	0.014
NOTCH3	Q9UM47-1.2	P1807L	Neutral	0.233
NOTCH3	Q9UM47-1.2	P1807M	Neutral	0.062
NOTCH3	Q9UM47-1.2	P1807N	Neutral	0.069
NOTCH3	Q9UM47-1.2	P1807Q	Neutral	0.015
NOTCH3	Q9UM47-1.2	P1807R	Neutral	0.058
NOTCH3	Q9UM47-1.2	P1807S	Neutral	0.015
NOTCH3	Q9UM47-1.2	P1807T	Neutral	0.016
NOTCH3	Q9UM47-1.2	P1807V	Neutral	0.067
NOTCH3	Q9UM47-1.2	P1807W	Pathogenic	0.544
NOTCH3	Q9UM47-1.2	P1807Y	Neutral	0.22
NOTCH3	Q9UM47-1.2	T1808A	Neutral	0.002
NOTCH3	Q9UM47-1.2	T1808C	Neutral	0.011
NOTCH3	Q9UM47-1.2	T1808D	Neutral	0.011
NOTCH3	Q9UM47-1.2	T1808E	Neutral	0.011
NOTCH3	Q9UM47-1.2	T1808F	Neutral	0.043
NOTCH3	Q9UM47-1.2	T1808G	Neutral	0.042
NOTCH3	Q9UM47-1.2	T1808H	Neutral	0.045
NOTCH3	Q9UM47-1.2	T1808I	Neutral	0.01
NOTCH3	Q9UM47-1.2	T1808K	Neutral	0.01
NOTCH3	Q9UM47-1.2	T1808L	Neutral	0.01
NOTCH3	Q9UM47-1.2	T1808M	Neutral	0.01
NOTCH3	Q9UM47-1.2	T1808N	Neutral	0.003
NOTCH3	Q9UM47-1.2	T1808P	Neutral	0.011
NOTCH3	Q9UM47-1.2	T1808Q	Neutral	0.011
NOTCH3	Q9UM47-1.2	T1808R	Neutral	0.009
NOTCH3	Q9UM47-1.2	T1808S	Neutral	0.001
NOTCH3	Q9UM47-1.2	T1808V	Neutral	0.002
NOTCH3	Q9UM47-1.2	T1808W	Neutral	0.039
NOTCH3	Q9UM47-1.2	T1808Y	Neutral	0.042
NOTCH3	Q9UM47-1.2	E1809A	Neutral	0.248
NOTCH3	Q9UM47-1.2	E1809C	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	E1809D	Neutral	0.004
NOTCH3	Q9UM47-1.2	E1809F	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	E1809G	Pathogenic	0.581
NOTCH3	Q9UM47-1.2	E1809H	Neutral	0.076
NOTCH3	Q9UM47-1.2	E1809I	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	E1809K	Neutral	0.017
NOTCH3	Q9UM47-1.2	E1809L	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	E1809M	Pathogenic	0.626
NOTCH3	Q9UM47-1.2	E1809N	Neutral	0.074
NOTCH3	Q9UM47-1.2	E1809P	Neutral	0.265
NOTCH3	Q9UM47-1.2	E1809Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	E1809R	Neutral	0.068
NOTCH3	Q9UM47-1.2	E1809S	Neutral	0.069
NOTCH3	Q9UM47-1.2	E1809T	Neutral	0.267
NOTCH3	Q9UM47-1.2	E1809V	Pathogenic	0.636
NOTCH3	Q9UM47-1.2	E1809W	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	E1809Y	Pathogenic	0.61
NOTCH3	Q9UM47-1.2	E1810A	Neutral	0.4
NOTCH3	Q9UM47-1.2	E1810C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	E1810D	Neutral	0.008
NOTCH3	Q9UM47-1.2	E1810F	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	E1810G	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	E1810H	Neutral	0.142
NOTCH3	Q9UM47-1.2	E1810I	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	E1810K	Neutral	0.033
NOTCH3	Q9UM47-1.2	E1810L	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	E1810M	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	E1810N	Neutral	0.14
NOTCH3	Q9UM47-1.2	E1810P	Neutral	0.422
NOTCH3	Q9UM47-1.2	E1810Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	E1810R	Neutral	0.129
NOTCH3	Q9UM47-1.2	E1810S	Neutral	0.13
NOTCH3	Q9UM47-1.2	E1810T	Neutral	0.424
NOTCH3	Q9UM47-1.2	E1810V	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	E1810W	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	E1810Y	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	D1811A	Neutral	0.276
NOTCH3	Q9UM47-1.2	D1811C	Pathogenic	0.652
NOTCH3	Q9UM47-1.2	D1811E	Neutral	0.001
NOTCH3	Q9UM47-1.2	D1811F	Pathogenic	0.619
NOTCH3	Q9UM47-1.2	D1811G	Neutral	0.072
NOTCH3	Q9UM47-1.2	D1811H	Neutral	0.076
NOTCH3	Q9UM47-1.2	D1811I	Pathogenic	0.629
NOTCH3	Q9UM47-1.2	D1811K	Neutral	0.071
NOTCH3	Q9UM47-1.2	D1811L	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	D1811M	Pathogenic	0.628
NOTCH3	Q9UM47-1.2	D1811N	Neutral	0.004
NOTCH3	Q9UM47-1.2	D1811P	Neutral	0.084
NOTCH3	Q9UM47-1.2	D1811Q	Neutral	0.018
NOTCH3	Q9UM47-1.2	D1811R	Neutral	0.25
NOTCH3	Q9UM47-1.2	D1811S	Neutral	0.018
NOTCH3	Q9UM47-1.2	D1811T	Neutral	0.083
NOTCH3	Q9UM47-1.2	D1811V	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	D1811W	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	D1811Y	Pathogenic	0.612
NOTCH3	Q9UM47-1.2	E1812A	Neutral	0.458
NOTCH3	Q9UM47-1.2	E1812C	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E1812D	Neutral	0.01
NOTCH3	Q9UM47-1.2	E1812F	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	E1812G	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	E1812H	Neutral	0.174
NOTCH3	Q9UM47-1.2	E1812I	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	E1812K	Neutral	0.041
NOTCH3	Q9UM47-1.2	E1812L	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	E1812M	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	E1812N	Neutral	0.171
NOTCH3	Q9UM47-1.2	E1812P	Neutral	0.481
NOTCH3	Q9UM47-1.2	E1812Q	Neutral	0.01
NOTCH3	Q9UM47-1.2	E1812R	Neutral	0.158
NOTCH3	Q9UM47-1.2	E1812S	Neutral	0.159
NOTCH3	Q9UM47-1.2	E1812T	Neutral	0.483
NOTCH3	Q9UM47-1.2	E1812V	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	E1812W	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	E1812Y	Pathogenic	0.801
NOTCH3	Q9UM47-1.2	A1813C	Neutral	0.019
NOTCH3	Q9UM47-1.2	A1813D	Neutral	0.285
NOTCH3	Q9UM47-1.2	A1813E	Neutral	0.075
NOTCH3	Q9UM47-1.2	A1813F	Neutral	0.252
NOTCH3	Q9UM47-1.2	A1813G	Neutral	0.019
NOTCH3	Q9UM47-1.2	A1813H	Neutral	0.263
NOTCH3	Q9UM47-1.2	A1813I	Neutral	0.072
NOTCH3	Q9UM47-1.2	A1813K	Neutral	0.069
NOTCH3	Q9UM47-1.2	A1813L	Neutral	0.072
NOTCH3	Q9UM47-1.2	A1813M	Neutral	0.071
NOTCH3	Q9UM47-1.2	A1813N	Neutral	0.281
NOTCH3	Q9UM47-1.2	A1813P	Neutral	0.08
NOTCH3	Q9UM47-1.2	A1813Q	Neutral	0.074
NOTCH3	Q9UM47-1.2	A1813R	Neutral	0.066
NOTCH3	Q9UM47-1.2	A1813S	Neutral	0.004
NOTCH3	Q9UM47-1.2	A1813T	Neutral	0.019
NOTCH3	Q9UM47-1.2	A1813V	Neutral	0.018
NOTCH3	Q9UM47-1.2	A1813W	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	A1813Y	Neutral	0.246
NOTCH3	Q9UM47-1.2	D1814A	Neutral	0.28
NOTCH3	Q9UM47-1.2	D1814C	Pathogenic	0.657
NOTCH3	Q9UM47-1.2	D1814E	Neutral	0.001
NOTCH3	Q9UM47-1.2	D1814F	Pathogenic	0.624
NOTCH3	Q9UM47-1.2	D1814G	Neutral	0.073
NOTCH3	Q9UM47-1.2	D1814H	Neutral	0.078
NOTCH3	Q9UM47-1.2	D1814I	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	D1814K	Neutral	0.073
NOTCH3	Q9UM47-1.2	D1814L	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	D1814M	Pathogenic	0.633
NOTCH3	Q9UM47-1.2	D1814N	Neutral	0.004
NOTCH3	Q9UM47-1.2	D1814P	Neutral	0.086
NOTCH3	Q9UM47-1.2	D1814Q	Neutral	0.018
NOTCH3	Q9UM47-1.2	D1814R	Neutral	0.254
NOTCH3	Q9UM47-1.2	D1814S	Neutral	0.019
NOTCH3	Q9UM47-1.2	D1814T	Neutral	0.085
NOTCH3	Q9UM47-1.2	D1814V	Pathogenic	0.649
NOTCH3	Q9UM47-1.2	D1814W	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	D1814Y	Pathogenic	0.617
NOTCH3	Q9UM47-1.2	D1815A	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	D1815C	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	D1815E	Neutral	0.016
NOTCH3	Q9UM47-1.2	D1815F	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	D1815G	Pathogenic	0.582
NOTCH3	Q9UM47-1.2	D1815H	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	D1815I	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	D1815K	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	D1815L	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	D1815M	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	D1815N	Neutral	0.072
NOTCH3	Q9UM47-1.2	D1815P	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	D1815Q	Neutral	0.248
NOTCH3	Q9UM47-1.2	D1815R	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	D1815S	Neutral	0.252
NOTCH3	Q9UM47-1.2	D1815T	Pathogenic	0.62
NOTCH3	Q9UM47-1.2	D1815V	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	D1815W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	D1815Y	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	T1816A	Neutral	0.004
NOTCH3	Q9UM47-1.2	T1816C	Neutral	0.02
NOTCH3	Q9UM47-1.2	T1816D	Neutral	0.02
NOTCH3	Q9UM47-1.2	T1816E	Neutral	0.019
NOTCH3	Q9UM47-1.2	T1816F	Neutral	0.075
NOTCH3	Q9UM47-1.2	T1816G	Neutral	0.074
NOTCH3	Q9UM47-1.2	T1816H	Neutral	0.079
NOTCH3	Q9UM47-1.2	T1816I	Neutral	0.018
NOTCH3	Q9UM47-1.2	T1816K	Neutral	0.018
NOTCH3	Q9UM47-1.2	T1816L	Neutral	0.018
NOTCH3	Q9UM47-1.2	T1816M	Neutral	0.018
NOTCH3	Q9UM47-1.2	T1816N	Neutral	0.005
NOTCH3	Q9UM47-1.2	T1816P	Neutral	0.02
NOTCH3	Q9UM47-1.2	T1816Q	Neutral	0.019
NOTCH3	Q9UM47-1.2	T1816R	Neutral	0.017
NOTCH3	Q9UM47-1.2	T1816S	Neutral	0.001
NOTCH3	Q9UM47-1.2	T1816V	Neutral	0.004
NOTCH3	Q9UM47-1.2	T1816W	Neutral	0.068
NOTCH3	Q9UM47-1.2	T1816Y	Neutral	0.073
NOTCH3	Q9UM47-1.2	S1817A	Neutral	0.015
NOTCH3	Q9UM47-1.2	S1817C	Neutral	0.233
NOTCH3	Q9UM47-1.2	S1817D	Neutral	0.061
NOTCH3	Q9UM47-1.2	S1817E	Neutral	0.057
NOTCH3	Q9UM47-1.2	S1817F	Pathogenic	0.536
NOTCH3	Q9UM47-1.2	S1817G	Neutral	0.06
NOTCH3	Q9UM47-1.2	S1817H	Neutral	0.211
NOTCH3	Q9UM47-1.2	S1817I	Pathogenic	0.546
NOTCH3	Q9UM47-1.2	S1817K	Neutral	0.052
NOTCH3	Q9UM47-1.2	S1817L	Pathogenic	0.546
NOTCH3	Q9UM47-1.2	S1817M	Neutral	0.208
NOTCH3	Q9UM47-1.2	S1817N	Neutral	0.014
NOTCH3	Q9UM47-1.2	S1817P	Neutral	0.23
NOTCH3	Q9UM47-1.2	S1817Q	Neutral	0.056
NOTCH3	Q9UM47-1.2	S1817R	Neutral	0.193
NOTCH3	Q9UM47-1.2	S1817T	Neutral	0.014
NOTCH3	Q9UM47-1.2	S1817V	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	S1817W	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	S1817Y	Pathogenic	0.528
NOTCH3	Q9UM47-1.2	A1818C	Neutral	0.241
NOTCH3	Q9UM47-1.2	A1818D	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	A1818E	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	A1818F	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	A1818G	Neutral	0.24
NOTCH3	Q9UM47-1.2	A1818H	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	A1818I	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	A1818K	Pathogenic	0.546
NOTCH3	Q9UM47-1.2	A1818L	Pathogenic	0.556
NOTCH3	Q9UM47-1.2	A1818M	Pathogenic	0.555
NOTCH3	Q9UM47-1.2	A1818N	Pathogenic	0.864
NOTCH3	Q9UM47-1.2	A1818P	Pathogenic	0.586
NOTCH3	Q9UM47-1.2	A1818Q	Pathogenic	0.564
NOTCH3	Q9UM47-1.2	A1818R	Pathogenic	0.533
NOTCH3	Q9UM47-1.2	A1818S	Neutral	0.068
NOTCH3	Q9UM47-1.2	A1818T	Neutral	0.235
NOTCH3	Q9UM47-1.2	A1818V	Neutral	0.228
NOTCH3	Q9UM47-1.2	A1818W	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	A1818Y	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	S1819A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1819C	Neutral	0.026
NOTCH3	Q9UM47-1.2	S1819D	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1819E	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1819F	Neutral	0.093
NOTCH3	Q9UM47-1.2	S1819G	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1819H	Neutral	0.023
NOTCH3	Q9UM47-1.2	S1819I	Neutral	0.097
NOTCH3	Q9UM47-1.2	S1819K	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1819L	Neutral	0.097
NOTCH3	Q9UM47-1.2	S1819M	Neutral	0.023
NOTCH3	Q9UM47-1.2	S1819N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1819P	Neutral	0.026
NOTCH3	Q9UM47-1.2	S1819Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1819R	Neutral	0.021
NOTCH3	Q9UM47-1.2	S1819T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1819V	Neutral	0.103
NOTCH3	Q9UM47-1.2	S1819W	Neutral	0.297
NOTCH3	Q9UM47-1.2	S1819Y	Neutral	0.091
NOTCH3	Q9UM47-1.2	I1820A	Pathogenic	0.519
NOTCH3	Q9UM47-1.2	I1820C	Pathogenic	0.536
NOTCH3	Q9UM47-1.2	I1820D	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	I1820E	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	I1820F	Neutral	0.218
NOTCH3	Q9UM47-1.2	I1820G	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	I1820H	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	I1820K	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	I1820L	Neutral	0.014
NOTCH3	Q9UM47-1.2	I1820M	Neutral	0.06
NOTCH3	Q9UM47-1.2	I1820N	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	I1820P	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	I1820Q	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	I1820R	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	I1820S	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	I1820T	Pathogenic	0.544
NOTCH3	Q9UM47-1.2	I1820V	Neutral	0.003
NOTCH3	Q9UM47-1.2	I1820W	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	I1820Y	Pathogenic	0.556
NOTCH3	Q9UM47-1.2	I1821A	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	I1821C	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	I1821D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1821E	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1821F	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	I1821G	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	I1821H	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1821K	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1821L	Neutral	0.124
NOTCH3	Q9UM47-1.2	I1821M	Neutral	0.392
NOTCH3	Q9UM47-1.2	I1821N	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1821P	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1821Q	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1821R	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1821S	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	I1821T	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	I1821V	Neutral	0.028
NOTCH3	Q9UM47-1.2	I1821W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1821Y	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	S1822A	Neutral	0.014
NOTCH3	Q9UM47-1.2	S1822C	Neutral	0.229
NOTCH3	Q9UM47-1.2	S1822D	Neutral	0.06
NOTCH3	Q9UM47-1.2	S1822E	Neutral	0.056
NOTCH3	Q9UM47-1.2	S1822F	Pathogenic	0.53
NOTCH3	Q9UM47-1.2	S1822G	Neutral	0.058
NOTCH3	Q9UM47-1.2	S1822H	Neutral	0.207
NOTCH3	Q9UM47-1.2	S1822I	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	S1822K	Neutral	0.051
NOTCH3	Q9UM47-1.2	S1822L	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	S1822M	Neutral	0.204
NOTCH3	Q9UM47-1.2	S1822N	Neutral	0.014
NOTCH3	Q9UM47-1.2	S1822P	Neutral	0.226
NOTCH3	Q9UM47-1.2	S1822Q	Neutral	0.055
NOTCH3	Q9UM47-1.2	S1822R	Neutral	0.189
NOTCH3	Q9UM47-1.2	S1822T	Neutral	0.014
NOTCH3	Q9UM47-1.2	S1822V	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	S1822W	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	S1822Y	Pathogenic	0.522
NOTCH3	Q9UM47-1.2	D1823A	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	D1823C	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D1823E	Neutral	0.027
NOTCH3	Q9UM47-1.2	D1823F	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	D1823G	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	D1823H	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	D1823I	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	D1823K	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	D1823L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1823M	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	D1823N	Neutral	0.117
NOTCH3	Q9UM47-1.2	D1823P	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	D1823Q	Neutral	0.362
NOTCH3	Q9UM47-1.2	D1823R	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	D1823S	Neutral	0.367
NOTCH3	Q9UM47-1.2	D1823T	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	D1823V	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D1823W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D1823Y	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	L1824A	Neutral	0.336
NOTCH3	Q9UM47-1.2	L1824C	Neutral	0.352
NOTCH3	Q9UM47-1.2	L1824D	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L1824E	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	L1824F	Neutral	0.116
NOTCH3	Q9UM47-1.2	L1824G	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	L1824H	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	L1824I	Neutral	0.007
NOTCH3	Q9UM47-1.2	L1824K	Pathogenic	0.736
NOTCH3	Q9UM47-1.2	L1824M	Neutral	0.007
NOTCH3	Q9UM47-1.2	L1824N	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	L1824P	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	L1824Q	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	L1824R	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	L1824S	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	L1824T	Neutral	0.359
NOTCH3	Q9UM47-1.2	L1824V	Neutral	0.027
NOTCH3	Q9UM47-1.2	L1824W	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	L1824Y	Neutral	0.37
NOTCH3	Q9UM47-1.2	I1825A	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	I1825C	Pathogenic	0.753
NOTCH3	Q9UM47-1.2	I1825D	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	I1825E	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	I1825F	Neutral	0.425
NOTCH3	Q9UM47-1.2	I1825G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1825H	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	I1825K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	I1825L	Neutral	0.036
NOTCH3	Q9UM47-1.2	I1825M	Neutral	0.145
NOTCH3	Q9UM47-1.2	I1825N	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	I1825P	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	I1825Q	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	I1825R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	I1825S	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	I1825T	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	I1825V	Neutral	0.008
NOTCH3	Q9UM47-1.2	I1825W	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	I1825Y	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	C1826A	Neutral	0.003
NOTCH3	Q9UM47-1.2	C1826D	Neutral	0.261
NOTCH3	Q9UM47-1.2	C1826E	Pathogenic	0.599
NOTCH3	Q9UM47-1.2	C1826F	Neutral	0.061
NOTCH3	Q9UM47-1.2	C1826G	Neutral	0.236
NOTCH3	Q9UM47-1.2	C1826H	Neutral	0.24
NOTCH3	Q9UM47-1.2	C1826I	Neutral	0.015
NOTCH3	Q9UM47-1.2	C1826K	Neutral	0.23
NOTCH3	Q9UM47-1.2	C1826L	Neutral	0.015
NOTCH3	Q9UM47-1.2	C1826M	Neutral	0.015
NOTCH3	Q9UM47-1.2	C1826N	Neutral	0.257
NOTCH3	Q9UM47-1.2	C1826P	Neutral	0.259
NOTCH3	Q9UM47-1.2	C1826Q	Neutral	0.243
NOTCH3	Q9UM47-1.2	C1826R	Neutral	0.221
NOTCH3	Q9UM47-1.2	C1826S	Neutral	0.016
NOTCH3	Q9UM47-1.2	C1826T	Neutral	0.016
NOTCH3	Q9UM47-1.2	C1826V	Neutral	0.016
NOTCH3	Q9UM47-1.2	C1826W	Neutral	0.055
NOTCH3	Q9UM47-1.2	C1826Y	Neutral	0.059
NOTCH3	Q9UM47-1.2	Q1827A	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	Q1827C	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	Q1827D	Neutral	0.489
NOTCH3	Q9UM47-1.2	Q1827E	Neutral	0.047
NOTCH3	Q9UM47-1.2	Q1827F	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	Q1827G	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	Q1827H	Pathogenic	0.507
NOTCH3	Q9UM47-1.2	Q1827I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	Q1827K	Neutral	0.175
NOTCH3	Q9UM47-1.2	Q1827L	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	Q1827M	Pathogenic	0.503
NOTCH3	Q9UM47-1.2	Q1827N	Neutral	0.493
NOTCH3	Q9UM47-1.2	Q1827P	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	Q1827R	Neutral	0.168
NOTCH3	Q9UM47-1.2	Q1827S	Neutral	0.471
NOTCH3	Q9UM47-1.2	Q1827T	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	Q1827V	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	Q1827W	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	Q1827Y	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	G1828A	Neutral	0.232
NOTCH3	Q9UM47-1.2	G1828C	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G1828D	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	G1828E	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	G1828F	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G1828H	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G1828I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1828K	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G1828L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1828M	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G1828N	Neutral	0.213
NOTCH3	Q9UM47-1.2	G1828P	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	G1828Q	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	G1828R	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	G1828S	Neutral	0.227
NOTCH3	Q9UM47-1.2	G1828T	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	G1828V	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G1828W	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	G1828Y	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	A1829C	Neutral	0.38
NOTCH3	Q9UM47-1.2	A1829D	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	A1829E	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	A1829F	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	A1829G	Neutral	0.379
NOTCH3	Q9UM47-1.2	A1829H	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	A1829I	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	A1829K	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	A1829L	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	A1829M	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	A1829N	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	A1829P	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	A1829Q	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	A1829R	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	A1829S	Neutral	0.124
NOTCH3	Q9UM47-1.2	A1829T	Neutral	0.372
NOTCH3	Q9UM47-1.2	A1829V	Neutral	0.363
NOTCH3	Q9UM47-1.2	A1829W	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	A1829Y	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	Q1830A	Neutral	0.037
NOTCH3	Q9UM47-1.2	Q1830C	Neutral	0.46
NOTCH3	Q9UM47-1.2	Q1830D	Neutral	0.009
NOTCH3	Q9UM47-1.2	Q1830E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q1830F	Neutral	0.469
NOTCH3	Q9UM47-1.2	Q1830G	Neutral	0.138
NOTCH3	Q9UM47-1.2	Q1830H	Neutral	0.01
NOTCH3	Q9UM47-1.2	Q1830I	Neutral	0.479
NOTCH3	Q9UM47-1.2	Q1830K	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q1830L	Neutral	0.168
NOTCH3	Q9UM47-1.2	Q1830M	Neutral	0.01
NOTCH3	Q9UM47-1.2	Q1830N	Neutral	0.009
NOTCH3	Q9UM47-1.2	Q1830P	Neutral	0.04
NOTCH3	Q9UM47-1.2	Q1830R	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q1830S	Neutral	0.008
NOTCH3	Q9UM47-1.2	Q1830T	Neutral	0.04
NOTCH3	Q9UM47-1.2	Q1830V	Neutral	0.168
NOTCH3	Q9UM47-1.2	Q1830W	Neutral	0.149
NOTCH3	Q9UM47-1.2	Q1830Y	Neutral	0.04
NOTCH3	Q9UM47-1.2	L1831A	Pathogenic	0.647
NOTCH3	Q9UM47-1.2	L1831C	Pathogenic	0.662
NOTCH3	Q9UM47-1.2	L1831D	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1831E	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	L1831F	Neutral	0.322
NOTCH3	Q9UM47-1.2	L1831G	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	L1831H	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	L1831I	Neutral	0.023
NOTCH3	Q9UM47-1.2	L1831K	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	L1831M	Neutral	0.023
NOTCH3	Q9UM47-1.2	L1831N	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	L1831P	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	L1831Q	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	L1831R	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	L1831S	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	L1831T	Pathogenic	0.669
NOTCH3	Q9UM47-1.2	L1831V	Neutral	0.092
NOTCH3	Q9UM47-1.2	L1831W	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	L1831Y	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	G1832A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1832C	Neutral	0.125
NOTCH3	Q9UM47-1.2	G1832D	Neutral	0.007
NOTCH3	Q9UM47-1.2	G1832E	Neutral	0.028
NOTCH3	Q9UM47-1.2	G1832F	Neutral	0.107
NOTCH3	Q9UM47-1.2	G1832H	Neutral	0.027
NOTCH3	Q9UM47-1.2	G1832I	Neutral	0.362
NOTCH3	Q9UM47-1.2	G1832K	Neutral	0.025
NOTCH3	Q9UM47-1.2	G1832L	Neutral	0.362
NOTCH3	Q9UM47-1.2	G1832M	Neutral	0.11
NOTCH3	Q9UM47-1.2	G1832N	Neutral	0.001
NOTCH3	Q9UM47-1.2	G1832P	Neutral	0.03
NOTCH3	Q9UM47-1.2	G1832Q	Neutral	0.027
NOTCH3	Q9UM47-1.2	G1832R	Neutral	0.024
NOTCH3	Q9UM47-1.2	G1832S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G1832T	Neutral	0.03
NOTCH3	Q9UM47-1.2	G1832V	Neutral	0.118
NOTCH3	Q9UM47-1.2	G1832W	Neutral	0.023
NOTCH3	Q9UM47-1.2	G1832Y	Neutral	0.104
NOTCH3	Q9UM47-1.2	A1833C	Neutral	0.102
NOTCH3	Q9UM47-1.2	A1833D	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	A1833E	Neutral	0.322
NOTCH3	Q9UM47-1.2	A1833F	Pathogenic	0.663
NOTCH3	Q9UM47-1.2	A1833G	Neutral	0.102
NOTCH3	Q9UM47-1.2	A1833H	Pathogenic	0.675
NOTCH3	Q9UM47-1.2	A1833I	Neutral	0.31
NOTCH3	Q9UM47-1.2	A1833K	Neutral	0.301
NOTCH3	Q9UM47-1.2	A1833L	Neutral	0.31
NOTCH3	Q9UM47-1.2	A1833M	Neutral	0.309
NOTCH3	Q9UM47-1.2	A1833N	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	A1833P	Neutral	0.337
NOTCH3	Q9UM47-1.2	A1833Q	Neutral	0.317
NOTCH3	Q9UM47-1.2	A1833R	Neutral	0.291
NOTCH3	Q9UM47-1.2	A1833S	Neutral	0.026
NOTCH3	Q9UM47-1.2	A1833T	Neutral	0.099
NOTCH3	Q9UM47-1.2	A1833V	Neutral	0.096
NOTCH3	Q9UM47-1.2	A1833W	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	A1833Y	Pathogenic	0.656
NOTCH3	Q9UM47-1.2	R1834A	Neutral	0.061
NOTCH3	Q9UM47-1.2	R1834C	Pathogenic	0.592
NOTCH3	Q9UM47-1.2	R1834D	Neutral	0.243
NOTCH3	Q9UM47-1.2	R1834E	Neutral	0.016
NOTCH3	Q9UM47-1.2	R1834F	Pathogenic	0.638
NOTCH3	Q9UM47-1.2	R1834G	Neutral	0.214
NOTCH3	Q9UM47-1.2	R1834H	Neutral	0.017
NOTCH3	Q9UM47-1.2	R1834I	Pathogenic	0.628
NOTCH3	Q9UM47-1.2	R1834K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R1834L	Neutral	0.271
NOTCH3	Q9UM47-1.2	R1834M	Neutral	0.075
NOTCH3	Q9UM47-1.2	R1834N	Neutral	0.016
NOTCH3	Q9UM47-1.2	R1834P	Neutral	0.244
NOTCH3	Q9UM47-1.2	R1834Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	R1834S	Neutral	0.062
NOTCH3	Q9UM47-1.2	R1834T	Neutral	0.067
NOTCH3	Q9UM47-1.2	R1834V	Pathogenic	0.61
NOTCH3	Q9UM47-1.2	R1834W	Pathogenic	0.637
NOTCH3	Q9UM47-1.2	R1834Y	Neutral	0.283
NOTCH3	Q9UM47-1.2	T1835A	Neutral	0.361
NOTCH3	Q9UM47-1.2	T1835C	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	T1835D	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	T1835E	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	T1835F	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	T1835G	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	T1835H	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	T1835I	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	T1835K	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	T1835L	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	T1835M	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	T1835N	Neutral	0.383
NOTCH3	Q9UM47-1.2	T1835P	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	T1835Q	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	T1835R	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	T1835S	Neutral	0.113
NOTCH3	Q9UM47-1.2	T1835V	Neutral	0.375
NOTCH3	Q9UM47-1.2	T1835W	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	T1835Y	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	D1836A	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	D1836C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1836E	Neutral	0.03
NOTCH3	Q9UM47-1.2	D1836F	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D1836G	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	D1836H	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	D1836I	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D1836K	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	D1836L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1836M	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D1836N	Neutral	0.13
NOTCH3	Q9UM47-1.2	D1836P	Pathogenic	0.761
NOTCH3	Q9UM47-1.2	D1836Q	Neutral	0.389
NOTCH3	Q9UM47-1.2	D1836R	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	D1836S	Neutral	0.394
NOTCH3	Q9UM47-1.2	D1836T	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	D1836V	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1836W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1836Y	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	R1837A	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	R1837C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	R1837D	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	R1837E	Neutral	0.444
NOTCH3	Q9UM47-1.2	R1837F	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	R1837G	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	R1837H	Neutral	0.454
NOTCH3	Q9UM47-1.2	R1837I	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	R1837K	Neutral	0.041
NOTCH3	Q9UM47-1.2	R1837L	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	R1837M	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	R1837N	Neutral	0.432
NOTCH3	Q9UM47-1.2	R1837P	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	R1837Q	Neutral	0.152
NOTCH3	Q9UM47-1.2	R1837S	Pathogenic	0.761
NOTCH3	Q9UM47-1.2	R1837T	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	R1837V	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	R1837W	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	R1837Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	T1838A	Neutral	0.394
NOTCH3	Q9UM47-1.2	T1838C	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	T1838D	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	T1838E	Pathogenic	0.756
NOTCH3	Q9UM47-1.2	T1838F	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	T1838G	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	T1838H	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	T1838I	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	T1838K	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	T1838L	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	T1838M	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	T1838N	Neutral	0.417
NOTCH3	Q9UM47-1.2	T1838P	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	T1838Q	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	T1838R	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	T1838S	Neutral	0.128
NOTCH3	Q9UM47-1.2	T1838V	Neutral	0.409
NOTCH3	Q9UM47-1.2	T1838W	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	T1838Y	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	G1839A	Neutral	0.232
NOTCH3	Q9UM47-1.2	G1839C	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G1839D	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	G1839E	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	G1839F	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G1839H	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	G1839I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1839K	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	G1839L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1839M	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	G1839N	Neutral	0.213
NOTCH3	Q9UM47-1.2	G1839P	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	G1839Q	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	G1839R	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	G1839S	Neutral	0.227
NOTCH3	Q9UM47-1.2	G1839T	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	G1839V	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G1839W	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	G1839Y	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	E1840A	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	E1840C	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	E1840D	Neutral	0.044
NOTCH3	Q9UM47-1.2	E1840F	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E1840G	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	E1840H	Neutral	0.496
NOTCH3	Q9UM47-1.2	E1840I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E1840K	Neutral	0.168
NOTCH3	Q9UM47-1.2	E1840L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E1840M	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	E1840N	Neutral	0.491
NOTCH3	Q9UM47-1.2	E1840P	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	E1840Q	Neutral	0.046
NOTCH3	Q9UM47-1.2	E1840R	Neutral	0.467
NOTCH3	Q9UM47-1.2	E1840S	Neutral	0.47
NOTCH3	Q9UM47-1.2	E1840T	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	E1840V	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	E1840W	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	E1840Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	T1841A	Neutral	0.212
NOTCH3	Q9UM47-1.2	T1841C	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	T1841D	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	T1841E	Pathogenic	0.561
NOTCH3	Q9UM47-1.2	T1841F	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	T1841G	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	T1841H	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	T1841I	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	T1841K	Pathogenic	0.537
NOTCH3	Q9UM47-1.2	T1841L	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	T1841M	Pathogenic	0.547
NOTCH3	Q9UM47-1.2	T1841N	Neutral	0.228
NOTCH3	Q9UM47-1.2	T1841P	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	T1841Q	Pathogenic	0.556
NOTCH3	Q9UM47-1.2	T1841R	Pathogenic	0.525
NOTCH3	Q9UM47-1.2	T1841S	Neutral	0.057
NOTCH3	Q9UM47-1.2	T1841V	Neutral	0.222
NOTCH3	Q9UM47-1.2	T1841W	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	T1841Y	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	A1842C	Neutral	0.259
NOTCH3	Q9UM47-1.2	A1842D	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	A1842E	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	A1842F	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	A1842G	Neutral	0.258
NOTCH3	Q9UM47-1.2	A1842H	Pathogenic	0.864
NOTCH3	Q9UM47-1.2	A1842I	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	A1842K	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	A1842L	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	A1842M	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	A1842N	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	A1842P	Pathogenic	0.61
NOTCH3	Q9UM47-1.2	A1842Q	Pathogenic	0.588
NOTCH3	Q9UM47-1.2	A1842R	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	A1842S	Neutral	0.074
NOTCH3	Q9UM47-1.2	A1842T	Neutral	0.253
NOTCH3	Q9UM47-1.2	A1842V	Neutral	0.246
NOTCH3	Q9UM47-1.2	A1842W	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	A1842Y	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	L1843A	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	L1843C	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	L1843D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1843E	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1843F	Neutral	0.376
NOTCH3	Q9UM47-1.2	L1843G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1843H	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1843I	Neutral	0.029
NOTCH3	Q9UM47-1.2	L1843K	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	L1843M	Neutral	0.029
NOTCH3	Q9UM47-1.2	L1843N	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1843P	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L1843Q	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	L1843R	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	L1843S	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	L1843T	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	L1843V	Neutral	0.114
NOTCH3	Q9UM47-1.2	L1843W	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	L1843Y	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	H1844A	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	H1844C	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1844D	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	H1844E	Pathogenic	0.721
NOTCH3	Q9UM47-1.2	H1844F	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	H1844G	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	H1844I	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1844K	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	H1844L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1844M	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	H1844N	Neutral	0.351
NOTCH3	Q9UM47-1.2	H1844P	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	H1844Q	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	H1844R	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	H1844S	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	H1844T	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	H1844V	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1844W	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	H1844Y	Neutral	0.106
NOTCH3	Q9UM47-1.2	L1845A	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	L1845C	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	L1845D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1845E	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1845F	Neutral	0.372
NOTCH3	Q9UM47-1.2	L1845G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1845H	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1845I	Neutral	0.029
NOTCH3	Q9UM47-1.2	L1845K	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	L1845M	Neutral	0.029
NOTCH3	Q9UM47-1.2	L1845N	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1845P	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L1845Q	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	L1845R	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	L1845S	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	L1845T	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	L1845V	Neutral	0.113
NOTCH3	Q9UM47-1.2	L1845W	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	L1845Y	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	A1846C	Neutral	0.39
NOTCH3	Q9UM47-1.2	A1846D	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	A1846E	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	A1846F	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	A1846G	Neutral	0.389
NOTCH3	Q9UM47-1.2	A1846H	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	A1846I	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	A1846K	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	A1846L	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	A1846M	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	A1846N	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	A1846P	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	A1846Q	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	A1846R	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	A1846S	Neutral	0.128
NOTCH3	Q9UM47-1.2	A1846T	Neutral	0.382
NOTCH3	Q9UM47-1.2	A1846V	Neutral	0.373
NOTCH3	Q9UM47-1.2	A1846W	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	A1846Y	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	A1847C	Neutral	0.389
NOTCH3	Q9UM47-1.2	A1847D	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	A1847E	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	A1847F	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	A1847G	Neutral	0.389
NOTCH3	Q9UM47-1.2	A1847H	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	A1847I	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	A1847K	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	A1847L	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	A1847M	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	A1847N	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	A1847P	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	A1847Q	Pathogenic	0.722
NOTCH3	Q9UM47-1.2	A1847R	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	A1847S	Neutral	0.128
NOTCH3	Q9UM47-1.2	A1847T	Neutral	0.382
NOTCH3	Q9UM47-1.2	A1847V	Neutral	0.372
NOTCH3	Q9UM47-1.2	A1847W	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	A1847Y	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	R1848A	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	R1848C	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1848D	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	R1848E	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	R1848F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1848G	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	R1848H	Pathogenic	0.589
NOTCH3	Q9UM47-1.2	R1848I	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1848K	Neutral	0.068
NOTCH3	Q9UM47-1.2	R1848L	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	R1848M	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	R1848N	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	R1848P	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	R1848Q	Neutral	0.236
NOTCH3	Q9UM47-1.2	R1848S	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	R1848T	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	R1848V	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1848W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1848Y	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	Y1849A	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	Y1849C	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	Y1849D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	Y1849E	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	Y1849F	Neutral	0.035
NOTCH3	Q9UM47-1.2	Y1849G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	Y1849H	Neutral	0.134
NOTCH3	Q9UM47-1.2	Y1849I	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	Y1849K	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	Y1849L	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	Y1849M	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	Y1849N	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	Y1849P	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	Y1849Q	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	Y1849R	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	Y1849S	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	Y1849T	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	Y1849V	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	Y1849W	Neutral	0.135
NOTCH3	Q9UM47-1.2	A1850C	Neutral	0.079
NOTCH3	Q9UM47-1.2	A1850D	Pathogenic	0.635
NOTCH3	Q9UM47-1.2	A1850E	Neutral	0.263
NOTCH3	Q9UM47-1.2	A1850F	Pathogenic	0.596
NOTCH3	Q9UM47-1.2	A1850G	Neutral	0.079
NOTCH3	Q9UM47-1.2	A1850H	Pathogenic	0.609
NOTCH3	Q9UM47-1.2	A1850I	Neutral	0.253
NOTCH3	Q9UM47-1.2	A1850K	Neutral	0.245
NOTCH3	Q9UM47-1.2	A1850L	Neutral	0.253
NOTCH3	Q9UM47-1.2	A1850M	Neutral	0.252
NOTCH3	Q9UM47-1.2	A1850N	Pathogenic	0.631
NOTCH3	Q9UM47-1.2	A1850P	Neutral	0.277
NOTCH3	Q9UM47-1.2	A1850Q	Neutral	0.259
NOTCH3	Q9UM47-1.2	A1850R	Neutral	0.235
NOTCH3	Q9UM47-1.2	A1850S	Neutral	0.019
NOTCH3	Q9UM47-1.2	A1850T	Neutral	0.076
NOTCH3	Q9UM47-1.2	A1850V	Neutral	0.074
NOTCH3	Q9UM47-1.2	A1850W	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	A1850Y	Pathogenic	0.589
NOTCH3	Q9UM47-1.2	R1851A	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	R1851C	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1851D	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	R1851E	Pathogenic	0.572
NOTCH3	Q9UM47-1.2	R1851F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1851G	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	R1851H	Pathogenic	0.582
NOTCH3	Q9UM47-1.2	R1851I	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1851K	Neutral	0.066
NOTCH3	Q9UM47-1.2	R1851L	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	R1851M	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	R1851N	Pathogenic	0.56
NOTCH3	Q9UM47-1.2	R1851P	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	R1851Q	Neutral	0.231
NOTCH3	Q9UM47-1.2	R1851S	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	R1851T	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	R1851V	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1851W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1851Y	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	A1852C	Neutral	0.125
NOTCH3	Q9UM47-1.2	A1852D	Pathogenic	0.744
NOTCH3	Q9UM47-1.2	A1852E	Neutral	0.374
NOTCH3	Q9UM47-1.2	A1852F	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	A1852G	Neutral	0.125
NOTCH3	Q9UM47-1.2	A1852H	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	A1852I	Neutral	0.361
NOTCH3	Q9UM47-1.2	A1852K	Neutral	0.351
NOTCH3	Q9UM47-1.2	A1852L	Neutral	0.361
NOTCH3	Q9UM47-1.2	A1852M	Neutral	0.36
NOTCH3	Q9UM47-1.2	A1852N	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	A1852P	Neutral	0.39
NOTCH3	Q9UM47-1.2	A1852Q	Neutral	0.368
NOTCH3	Q9UM47-1.2	A1852R	Neutral	0.34
NOTCH3	Q9UM47-1.2	A1852S	Neutral	0.032
NOTCH3	Q9UM47-1.2	A1852T	Neutral	0.122
NOTCH3	Q9UM47-1.2	A1852V	Neutral	0.117
NOTCH3	Q9UM47-1.2	A1852W	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	A1852Y	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	D1853A	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	D1853C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1853E	Neutral	0.031
NOTCH3	Q9UM47-1.2	D1853F	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D1853G	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	D1853H	Pathogenic	0.747
NOTCH3	Q9UM47-1.2	D1853I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1853K	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	D1853L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1853M	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1853N	Neutral	0.134
NOTCH3	Q9UM47-1.2	D1853P	Pathogenic	0.767
NOTCH3	Q9UM47-1.2	D1853Q	Neutral	0.397
NOTCH3	Q9UM47-1.2	D1853R	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	D1853S	Neutral	0.402
NOTCH3	Q9UM47-1.2	D1853T	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	D1853V	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1853W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1853Y	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	A1854C	Neutral	0.367
NOTCH3	Q9UM47-1.2	A1854D	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	A1854E	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	A1854F	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	A1854G	Neutral	0.366
NOTCH3	Q9UM47-1.2	A1854H	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	A1854I	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	A1854K	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	A1854L	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	A1854M	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	A1854N	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	A1854P	Pathogenic	0.722
NOTCH3	Q9UM47-1.2	A1854Q	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	A1854R	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	A1854S	Neutral	0.118
NOTCH3	Q9UM47-1.2	A1854T	Neutral	0.36
NOTCH3	Q9UM47-1.2	A1854V	Neutral	0.351
NOTCH3	Q9UM47-1.2	A1854W	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	A1854Y	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	A1855C	Neutral	0.384
NOTCH3	Q9UM47-1.2	A1855D	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	A1855E	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	A1855F	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	A1855G	Neutral	0.384
NOTCH3	Q9UM47-1.2	A1855H	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	A1855I	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	A1855K	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	A1855L	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	A1855M	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	A1855N	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	A1855P	Pathogenic	0.736
NOTCH3	Q9UM47-1.2	A1855Q	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	A1855R	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	A1855S	Neutral	0.126
NOTCH3	Q9UM47-1.2	A1855T	Neutral	0.377
NOTCH3	Q9UM47-1.2	A1855V	Neutral	0.368
NOTCH3	Q9UM47-1.2	A1855W	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	A1855Y	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	K1856A	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	K1856C	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	K1856D	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	K1856E	Neutral	0.384
NOTCH3	Q9UM47-1.2	K1856F	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	K1856G	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	K1856H	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	K1856I	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	K1856L	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	K1856M	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	K1856N	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	K1856P	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	K1856Q	Neutral	0.389
NOTCH3	Q9UM47-1.2	K1856R	Neutral	0.125
NOTCH3	Q9UM47-1.2	K1856S	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	K1856T	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	K1856V	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	K1856W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	K1856Y	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	R1857A	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	R1857C	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	R1857D	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	R1857E	Pathogenic	0.552
NOTCH3	Q9UM47-1.2	R1857F	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1857G	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	R1857H	Pathogenic	0.562
NOTCH3	Q9UM47-1.2	R1857I	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1857K	Neutral	0.062
NOTCH3	Q9UM47-1.2	R1857L	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	R1857M	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	R1857N	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	R1857P	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	R1857Q	Neutral	0.217
NOTCH3	Q9UM47-1.2	R1857S	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	R1857T	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	R1857V	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	R1857W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1857Y	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	L1858A	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	L1858C	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	L1858D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1858E	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1858F	Neutral	0.374
NOTCH3	Q9UM47-1.2	L1858G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1858H	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1858I	Neutral	0.029
NOTCH3	Q9UM47-1.2	L1858K	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	L1858M	Neutral	0.029
NOTCH3	Q9UM47-1.2	L1858N	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1858P	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L1858Q	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	L1858R	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	L1858S	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	L1858T	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	L1858V	Neutral	0.113
NOTCH3	Q9UM47-1.2	L1858W	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	L1858Y	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	L1859A	Pathogenic	0.702
NOTCH3	Q9UM47-1.2	L1859C	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	L1859D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1859E	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1859F	Neutral	0.379
NOTCH3	Q9UM47-1.2	L1859G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1859H	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1859I	Neutral	0.03
NOTCH3	Q9UM47-1.2	L1859K	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	L1859M	Neutral	0.03
NOTCH3	Q9UM47-1.2	L1859N	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1859P	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1859Q	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	L1859R	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	L1859S	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	L1859T	Pathogenic	0.722
NOTCH3	Q9UM47-1.2	L1859V	Neutral	0.115
NOTCH3	Q9UM47-1.2	L1859W	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	L1859Y	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	D1860A	Pathogenic	0.747
NOTCH3	Q9UM47-1.2	D1860C	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	D1860E	Neutral	0.007
NOTCH3	Q9UM47-1.2	D1860F	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	D1860G	Neutral	0.375
NOTCH3	Q9UM47-1.2	D1860H	Neutral	0.39
NOTCH3	Q9UM47-1.2	D1860I	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	D1860K	Neutral	0.373
NOTCH3	Q9UM47-1.2	D1860L	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1860M	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	D1860N	Neutral	0.032
NOTCH3	Q9UM47-1.2	D1860P	Neutral	0.415
NOTCH3	Q9UM47-1.2	D1860Q	Neutral	0.125
NOTCH3	Q9UM47-1.2	D1860R	Pathogenic	0.721
NOTCH3	Q9UM47-1.2	D1860S	Neutral	0.127
NOTCH3	Q9UM47-1.2	D1860T	Neutral	0.414
NOTCH3	Q9UM47-1.2	D1860V	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	D1860W	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	D1860Y	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	A1861C	Neutral	0.319
NOTCH3	Q9UM47-1.2	A1861D	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	A1861E	Pathogenic	0.662
NOTCH3	Q9UM47-1.2	A1861F	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	A1861G	Neutral	0.319
NOTCH3	Q9UM47-1.2	A1861H	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	A1861I	Pathogenic	0.65
NOTCH3	Q9UM47-1.2	A1861K	Pathogenic	0.64
NOTCH3	Q9UM47-1.2	A1861L	Pathogenic	0.65
NOTCH3	Q9UM47-1.2	A1861M	Pathogenic	0.649
NOTCH3	Q9UM47-1.2	A1861N	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	A1861P	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	A1861Q	Pathogenic	0.657
NOTCH3	Q9UM47-1.2	A1861R	Pathogenic	0.628
NOTCH3	Q9UM47-1.2	A1861S	Neutral	0.098
NOTCH3	Q9UM47-1.2	A1861T	Neutral	0.312
NOTCH3	Q9UM47-1.2	A1861V	Neutral	0.304
NOTCH3	Q9UM47-1.2	A1861W	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	A1861Y	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	G1862A	Neutral	0.056
NOTCH3	Q9UM47-1.2	G1862C	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	G1862D	Neutral	0.199
NOTCH3	Q9UM47-1.2	G1862E	Pathogenic	0.513
NOTCH3	Q9UM47-1.2	G1862F	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	G1862H	Pathogenic	0.503
NOTCH3	Q9UM47-1.2	G1862I	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G1862K	Neutral	0.489
NOTCH3	Q9UM47-1.2	G1862L	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	G1862M	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	G1862N	Neutral	0.051
NOTCH3	Q9UM47-1.2	G1862P	Pathogenic	0.531
NOTCH3	Q9UM47-1.2	G1862Q	Pathogenic	0.507
NOTCH3	Q9UM47-1.2	G1862R	Neutral	0.476
NOTCH3	Q9UM47-1.2	G1862S	Neutral	0.055
NOTCH3	Q9UM47-1.2	G1862T	Pathogenic	0.528
NOTCH3	Q9UM47-1.2	G1862V	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	G1862W	Neutral	0.464
NOTCH3	Q9UM47-1.2	G1862Y	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	A1863C	Neutral	0.376
NOTCH3	Q9UM47-1.2	A1863D	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	A1863E	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	A1863F	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	A1863G	Neutral	0.375
NOTCH3	Q9UM47-1.2	A1863H	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	A1863I	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	A1863K	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	A1863L	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	A1863M	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	A1863N	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	A1863P	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	A1863Q	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	A1863R	Pathogenic	0.684
NOTCH3	Q9UM47-1.2	A1863S	Neutral	0.122
NOTCH3	Q9UM47-1.2	A1863T	Neutral	0.368
NOTCH3	Q9UM47-1.2	A1863V	Neutral	0.359
NOTCH3	Q9UM47-1.2	A1863W	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	A1863Y	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	D1864A	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	D1864C	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1864E	Neutral	0.029
NOTCH3	Q9UM47-1.2	D1864F	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D1864G	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	D1864H	Pathogenic	0.736
NOTCH3	Q9UM47-1.2	D1864I	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D1864K	Pathogenic	0.722
NOTCH3	Q9UM47-1.2	D1864L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1864M	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D1864N	Neutral	0.127
NOTCH3	Q9UM47-1.2	D1864P	Pathogenic	0.756
NOTCH3	Q9UM47-1.2	D1864Q	Neutral	0.383
NOTCH3	Q9UM47-1.2	D1864R	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	D1864S	Neutral	0.387
NOTCH3	Q9UM47-1.2	D1864T	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	D1864V	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1864W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1864Y	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	T1865A	Neutral	0.015
NOTCH3	Q9UM47-1.2	T1865C	Neutral	0.07
NOTCH3	Q9UM47-1.2	T1865D	Neutral	0.072
NOTCH3	Q9UM47-1.2	T1865E	Neutral	0.068
NOTCH3	Q9UM47-1.2	T1865F	Neutral	0.233
NOTCH3	Q9UM47-1.2	T1865G	Neutral	0.229
NOTCH3	Q9UM47-1.2	T1865H	Neutral	0.242
NOTCH3	Q9UM47-1.2	T1865I	Neutral	0.065
NOTCH3	Q9UM47-1.2	T1865K	Neutral	0.062
NOTCH3	Q9UM47-1.2	T1865L	Neutral	0.065
NOTCH3	Q9UM47-1.2	T1865M	Neutral	0.065
NOTCH3	Q9UM47-1.2	T1865N	Neutral	0.017
NOTCH3	Q9UM47-1.2	T1865P	Neutral	0.071
NOTCH3	Q9UM47-1.2	T1865Q	Neutral	0.067
NOTCH3	Q9UM47-1.2	T1865R	Neutral	0.059
NOTCH3	Q9UM47-1.2	T1865S	Neutral	0.003
NOTCH3	Q9UM47-1.2	T1865V	Neutral	0.016
NOTCH3	Q9UM47-1.2	T1865W	Neutral	0.214
NOTCH3	Q9UM47-1.2	T1865Y	Neutral	0.227
NOTCH3	Q9UM47-1.2	N1866A	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	N1866C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N1866D	Neutral	0.137
NOTCH3	Q9UM47-1.2	N1866E	Neutral	0.412
NOTCH3	Q9UM47-1.2	N1866F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N1866G	Neutral	0.381
NOTCH3	Q9UM47-1.2	N1866H	Neutral	0.13
NOTCH3	Q9UM47-1.2	N1866I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N1866K	Neutral	0.389
NOTCH3	Q9UM47-1.2	N1866L	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N1866M	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	N1866P	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	N1866Q	Neutral	0.408
NOTCH3	Q9UM47-1.2	N1866R	Neutral	0.377
NOTCH3	Q9UM47-1.2	N1866S	Neutral	0.13
NOTCH3	Q9UM47-1.2	N1866T	Neutral	0.423
NOTCH3	Q9UM47-1.2	N1866V	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N1866W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N1866Y	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	A1867C	Neutral	0.058
NOTCH3	Q9UM47-1.2	A1867D	Pathogenic	0.556
NOTCH3	Q9UM47-1.2	A1867E	Neutral	0.204
NOTCH3	Q9UM47-1.2	A1867F	Pathogenic	0.515
NOTCH3	Q9UM47-1.2	A1867G	Neutral	0.058
NOTCH3	Q9UM47-1.2	A1867H	Pathogenic	0.529
NOTCH3	Q9UM47-1.2	A1867I	Neutral	0.196
NOTCH3	Q9UM47-1.2	A1867K	Neutral	0.189
NOTCH3	Q9UM47-1.2	A1867L	Neutral	0.196
NOTCH3	Q9UM47-1.2	A1867M	Neutral	0.195
NOTCH3	Q9UM47-1.2	A1867N	Pathogenic	0.551
NOTCH3	Q9UM47-1.2	A1867P	Neutral	0.216
NOTCH3	Q9UM47-1.2	A1867Q	Neutral	0.201
NOTCH3	Q9UM47-1.2	A1867R	Neutral	0.181
NOTCH3	Q9UM47-1.2	A1867S	Neutral	0.014
NOTCH3	Q9UM47-1.2	A1867T	Neutral	0.056
NOTCH3	Q9UM47-1.2	A1867V	Neutral	0.054
NOTCH3	Q9UM47-1.2	A1867W	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	A1867Y	Pathogenic	0.508
NOTCH3	Q9UM47-1.2	Q1868A	Pathogenic	0.652
NOTCH3	Q9UM47-1.2	Q1868C	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	Q1868D	Neutral	0.311
NOTCH3	Q9UM47-1.2	Q1868E	Neutral	0.023
NOTCH3	Q9UM47-1.2	Q1868F	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	Q1868G	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	Q1868H	Neutral	0.327
NOTCH3	Q9UM47-1.2	Q1868I	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	Q1868K	Neutral	0.091
NOTCH3	Q9UM47-1.2	Q1868L	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	Q1868M	Neutral	0.324
NOTCH3	Q9UM47-1.2	Q1868N	Neutral	0.315
NOTCH3	Q9UM47-1.2	Q1868P	Pathogenic	0.673
NOTCH3	Q9UM47-1.2	Q1868R	Neutral	0.087
NOTCH3	Q9UM47-1.2	Q1868S	Neutral	0.296
NOTCH3	Q9UM47-1.2	Q1868T	Pathogenic	0.675
NOTCH3	Q9UM47-1.2	Q1868V	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	Q1868W	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	Q1868Y	Pathogenic	0.671
NOTCH3	Q9UM47-1.2	D1869A	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	D1869C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D1869E	Neutral	0.032
NOTCH3	Q9UM47-1.2	D1869F	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D1869G	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	D1869H	Pathogenic	0.75
NOTCH3	Q9UM47-1.2	D1869I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1869K	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	D1869L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1869M	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1869N	Neutral	0.136
NOTCH3	Q9UM47-1.2	D1869P	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	D1869Q	Neutral	0.4
NOTCH3	Q9UM47-1.2	D1869R	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	D1869S	Neutral	0.405
NOTCH3	Q9UM47-1.2	D1869T	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	D1869V	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1869W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1869Y	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	H1870A	Neutral	0.486
NOTCH3	Q9UM47-1.2	H1870C	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	H1870D	Neutral	0.186
NOTCH3	Q9UM47-1.2	H1870E	Neutral	0.051
NOTCH3	Q9UM47-1.2	H1870F	Neutral	0.193
NOTCH3	Q9UM47-1.2	H1870G	Neutral	0.468
NOTCH3	Q9UM47-1.2	H1870I	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	H1870K	Neutral	0.193
NOTCH3	Q9UM47-1.2	H1870L	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	H1870M	Pathogenic	0.531
NOTCH3	Q9UM47-1.2	H1870N	Neutral	0.011
NOTCH3	Q9UM47-1.2	H1870P	Pathogenic	0.509
NOTCH3	Q9UM47-1.2	H1870Q	Neutral	0.052
NOTCH3	Q9UM47-1.2	H1870R	Neutral	0.047
NOTCH3	Q9UM47-1.2	H1870S	Neutral	0.175
NOTCH3	Q9UM47-1.2	H1870T	Pathogenic	0.511
NOTCH3	Q9UM47-1.2	H1870V	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	H1870W	Neutral	0.496
NOTCH3	Q9UM47-1.2	H1870Y	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1871A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1871C	Neutral	0.029
NOTCH3	Q9UM47-1.2	S1871D	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1871E	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1871F	Neutral	0.103
NOTCH3	Q9UM47-1.2	S1871G	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1871H	Neutral	0.026
NOTCH3	Q9UM47-1.2	S1871I	Neutral	0.107
NOTCH3	Q9UM47-1.2	S1871K	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1871L	Neutral	0.107
NOTCH3	Q9UM47-1.2	S1871M	Neutral	0.026
NOTCH3	Q9UM47-1.2	S1871N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1871P	Neutral	0.029
NOTCH3	Q9UM47-1.2	S1871Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1871R	Neutral	0.023
NOTCH3	Q9UM47-1.2	S1871T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S1871V	Neutral	0.114
NOTCH3	Q9UM47-1.2	S1871W	Neutral	0.321
NOTCH3	Q9UM47-1.2	S1871Y	Neutral	0.101
NOTCH3	Q9UM47-1.2	G1872A	Neutral	0.24
NOTCH3	Q9UM47-1.2	G1872C	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	G1872D	Pathogenic	0.568
NOTCH3	Q9UM47-1.2	G1872E	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G1872F	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1872H	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	G1872I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1872K	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G1872L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1872M	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G1872N	Neutral	0.22
NOTCH3	Q9UM47-1.2	G1872P	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	G1872Q	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	G1872R	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	G1872S	Neutral	0.235
NOTCH3	Q9UM47-1.2	G1872T	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	G1872V	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G1872W	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	G1872Y	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	R1873A	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	R1873C	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	R1873D	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	R1873E	Pathogenic	0.566
NOTCH3	Q9UM47-1.2	R1873F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1873G	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	R1873H	Pathogenic	0.576
NOTCH3	Q9UM47-1.2	R1873I	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1873K	Neutral	0.065
NOTCH3	Q9UM47-1.2	R1873L	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	R1873M	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	R1873N	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	R1873P	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	R1873Q	Neutral	0.227
NOTCH3	Q9UM47-1.2	R1873S	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	R1873T	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	R1873V	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1873W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1873Y	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	T1874A	Neutral	0.222
NOTCH3	Q9UM47-1.2	T1874C	Pathogenic	0.584
NOTCH3	Q9UM47-1.2	T1874D	Pathogenic	0.59
NOTCH3	Q9UM47-1.2	T1874E	Pathogenic	0.576
NOTCH3	Q9UM47-1.2	T1874F	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	T1874G	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	T1874H	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	T1874I	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	T1874K	Pathogenic	0.552
NOTCH3	Q9UM47-1.2	T1874L	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	T1874M	Pathogenic	0.562
NOTCH3	Q9UM47-1.2	T1874N	Neutral	0.239
NOTCH3	Q9UM47-1.2	T1874P	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	T1874Q	Pathogenic	0.571
NOTCH3	Q9UM47-1.2	T1874R	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	T1874S	Neutral	0.06
NOTCH3	Q9UM47-1.2	T1874V	Neutral	0.233
NOTCH3	Q9UM47-1.2	T1874W	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	T1874Y	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	P1875A	Pathogenic	0.684
NOTCH3	Q9UM47-1.2	P1875C	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	P1875D	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	P1875E	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	P1875F	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	P1875G	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	P1875H	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	P1875I	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	P1875K	Pathogenic	0.668
NOTCH3	Q9UM47-1.2	P1875L	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	P1875M	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	P1875N	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	P1875Q	Pathogenic	0.684
NOTCH3	Q9UM47-1.2	P1875R	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	P1875S	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	P1875T	Pathogenic	0.701
NOTCH3	Q9UM47-1.2	P1875V	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	P1875W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P1875Y	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	L1876A	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	L1876C	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	L1876D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1876E	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1876F	Neutral	0.375
NOTCH3	Q9UM47-1.2	L1876G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1876H	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1876I	Neutral	0.029
NOTCH3	Q9UM47-1.2	L1876K	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	L1876M	Neutral	0.029
NOTCH3	Q9UM47-1.2	L1876N	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1876P	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L1876Q	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	L1876R	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	L1876S	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	L1876T	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	L1876V	Neutral	0.114
NOTCH3	Q9UM47-1.2	L1876W	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	L1876Y	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	H1877A	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	H1877C	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1877D	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	H1877E	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	H1877F	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	H1877G	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	H1877I	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1877K	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	H1877L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1877M	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	H1877N	Neutral	0.353
NOTCH3	Q9UM47-1.2	H1877P	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	H1877Q	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	H1877R	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	H1877S	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	H1877T	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	H1877V	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1877W	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	H1877Y	Neutral	0.107
NOTCH3	Q9UM47-1.2	T1878A	Neutral	0.015
NOTCH3	Q9UM47-1.2	T1878C	Neutral	0.072
NOTCH3	Q9UM47-1.2	T1878D	Neutral	0.073
NOTCH3	Q9UM47-1.2	T1878E	Neutral	0.069
NOTCH3	Q9UM47-1.2	T1878F	Neutral	0.236
NOTCH3	Q9UM47-1.2	T1878G	Neutral	0.232
NOTCH3	Q9UM47-1.2	T1878H	Neutral	0.246
NOTCH3	Q9UM47-1.2	T1878I	Neutral	0.066
NOTCH3	Q9UM47-1.2	T1878K	Neutral	0.063
NOTCH3	Q9UM47-1.2	T1878L	Neutral	0.066
NOTCH3	Q9UM47-1.2	T1878M	Neutral	0.066
NOTCH3	Q9UM47-1.2	T1878N	Neutral	0.017
NOTCH3	Q9UM47-1.2	T1878P	Neutral	0.073
NOTCH3	Q9UM47-1.2	T1878Q	Neutral	0.068
NOTCH3	Q9UM47-1.2	T1878R	Neutral	0.061
NOTCH3	Q9UM47-1.2	T1878S	Neutral	0.004
NOTCH3	Q9UM47-1.2	T1878V	Neutral	0.016
NOTCH3	Q9UM47-1.2	T1878W	Neutral	0.218
NOTCH3	Q9UM47-1.2	T1878Y	Neutral	0.231
NOTCH3	Q9UM47-1.2	A1879C	Neutral	0.379
NOTCH3	Q9UM47-1.2	A1879D	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	A1879E	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	A1879F	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	A1879G	Neutral	0.378
NOTCH3	Q9UM47-1.2	A1879H	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	A1879I	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	A1879K	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	A1879L	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	A1879M	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	A1879N	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	A1879P	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	A1879Q	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	A1879R	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	A1879S	Neutral	0.123
NOTCH3	Q9UM47-1.2	A1879T	Neutral	0.372
NOTCH3	Q9UM47-1.2	A1879V	Neutral	0.362
NOTCH3	Q9UM47-1.2	A1879W	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	A1879Y	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	V1880A	Neutral	0.493
NOTCH3	Q9UM47-1.2	V1880C	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	V1880D	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	V1880E	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	V1880F	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	V1880G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	V1880H	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	V1880I	Neutral	0.011
NOTCH3	Q9UM47-1.2	V1880K	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	V1880L	Neutral	0.186
NOTCH3	Q9UM47-1.2	V1880M	Neutral	0.186
NOTCH3	Q9UM47-1.2	V1880N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	V1880P	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	V1880Q	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	V1880R	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	V1880S	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	V1880T	Pathogenic	0.518
NOTCH3	Q9UM47-1.2	V1880W	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	V1880Y	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	T1881A	Neutral	0.012
NOTCH3	Q9UM47-1.2	T1881C	Neutral	0.057
NOTCH3	Q9UM47-1.2	T1881D	Neutral	0.058
NOTCH3	Q9UM47-1.2	T1881E	Neutral	0.055
NOTCH3	Q9UM47-1.2	T1881F	Neutral	0.194
NOTCH3	Q9UM47-1.2	T1881G	Neutral	0.19
NOTCH3	Q9UM47-1.2	T1881H	Neutral	0.202
NOTCH3	Q9UM47-1.2	T1881I	Neutral	0.052
NOTCH3	Q9UM47-1.2	T1881K	Neutral	0.05
NOTCH3	Q9UM47-1.2	T1881L	Neutral	0.052
NOTCH3	Q9UM47-1.2	T1881M	Neutral	0.052
NOTCH3	Q9UM47-1.2	T1881N	Neutral	0.013
NOTCH3	Q9UM47-1.2	T1881P	Neutral	0.057
NOTCH3	Q9UM47-1.2	T1881Q	Neutral	0.054
NOTCH3	Q9UM47-1.2	T1881R	Neutral	0.048
NOTCH3	Q9UM47-1.2	T1881S	Neutral	0.003
NOTCH3	Q9UM47-1.2	T1881V	Neutral	0.013
NOTCH3	Q9UM47-1.2	T1881W	Neutral	0.178
NOTCH3	Q9UM47-1.2	T1881Y	Neutral	0.189
NOTCH3	Q9UM47-1.2	A1882C	Neutral	0.351
NOTCH3	Q9UM47-1.2	A1882D	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	A1882E	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	A1882F	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	A1882G	Neutral	0.35
NOTCH3	Q9UM47-1.2	A1882H	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	A1882I	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	A1882K	Pathogenic	0.672
NOTCH3	Q9UM47-1.2	A1882L	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	A1882M	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	A1882N	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	A1882P	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	A1882Q	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	A1882R	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	A1882S	Neutral	0.111
NOTCH3	Q9UM47-1.2	A1882T	Neutral	0.344
NOTCH3	Q9UM47-1.2	A1882V	Neutral	0.335
NOTCH3	Q9UM47-1.2	A1882W	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	A1882Y	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	D1883A	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	D1883C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D1883E	Neutral	0.032
NOTCH3	Q9UM47-1.2	D1883F	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D1883G	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	D1883H	Pathogenic	0.75
NOTCH3	Q9UM47-1.2	D1883I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1883K	Pathogenic	0.736
NOTCH3	Q9UM47-1.2	D1883L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1883M	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1883N	Neutral	0.135
NOTCH3	Q9UM47-1.2	D1883P	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	D1883Q	Neutral	0.4
NOTCH3	Q9UM47-1.2	D1883R	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	D1883S	Neutral	0.405
NOTCH3	Q9UM47-1.2	D1883T	Pathogenic	0.767
NOTCH3	Q9UM47-1.2	D1883V	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1883W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1883Y	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	A1884C	Neutral	0.386
NOTCH3	Q9UM47-1.2	A1884D	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	A1884E	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	A1884F	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	A1884G	Neutral	0.385
NOTCH3	Q9UM47-1.2	A1884H	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	A1884I	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	A1884K	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	A1884L	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	A1884M	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	A1884N	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	A1884P	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	A1884Q	Pathogenic	0.72
NOTCH3	Q9UM47-1.2	A1884R	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	A1884S	Neutral	0.127
NOTCH3	Q9UM47-1.2	A1884T	Neutral	0.378
NOTCH3	Q9UM47-1.2	A1884V	Neutral	0.369
NOTCH3	Q9UM47-1.2	A1884W	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	A1884Y	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	Q1885A	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	Q1885C	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	Q1885D	Neutral	0.4
NOTCH3	Q9UM47-1.2	Q1885E	Neutral	0.033
NOTCH3	Q9UM47-1.2	Q1885F	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	Q1885G	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	Q1885H	Neutral	0.417
NOTCH3	Q9UM47-1.2	Q1885I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	Q1885K	Neutral	0.129
NOTCH3	Q9UM47-1.2	Q1885L	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	Q1885M	Neutral	0.414
NOTCH3	Q9UM47-1.2	Q1885N	Neutral	0.404
NOTCH3	Q9UM47-1.2	Q1885P	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	Q1885R	Neutral	0.123
NOTCH3	Q9UM47-1.2	Q1885S	Neutral	0.383
NOTCH3	Q9UM47-1.2	Q1885T	Pathogenic	0.753
NOTCH3	Q9UM47-1.2	Q1885V	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	Q1885W	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	Q1885Y	Pathogenic	0.75
NOTCH3	Q9UM47-1.2	G1886A	Neutral	0.227
NOTCH3	Q9UM47-1.2	G1886C	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G1886D	Pathogenic	0.551
NOTCH3	Q9UM47-1.2	G1886E	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	G1886F	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G1886H	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	G1886I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1886K	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	G1886L	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	G1886M	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	G1886N	Neutral	0.209
NOTCH3	Q9UM47-1.2	G1886P	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G1886Q	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	G1886R	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	G1886S	Neutral	0.223
NOTCH3	Q9UM47-1.2	G1886T	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G1886V	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G1886W	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	G1886Y	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	V1887A	Pathogenic	0.513
NOTCH3	Q9UM47-1.2	V1887C	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	V1887D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	V1887E	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	V1887F	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	V1887G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	V1887H	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	V1887I	Neutral	0.012
NOTCH3	Q9UM47-1.2	V1887K	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	V1887L	Neutral	0.199
NOTCH3	Q9UM47-1.2	V1887M	Neutral	0.198
NOTCH3	Q9UM47-1.2	V1887N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	V1887P	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	V1887Q	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	V1887R	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	V1887S	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	V1887T	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	V1887W	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	V1887Y	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	F1888A	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	F1888C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	F1888D	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1888E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1888G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F1888H	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	F1888I	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	F1888K	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1888L	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	F1888M	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	F1888N	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1888P	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	F1888Q	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1888R	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1888S	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	F1888T	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	F1888V	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	F1888W	Neutral	0.427
NOTCH3	Q9UM47-1.2	F1888Y	Neutral	0.038
NOTCH3	Q9UM47-1.2	Q1889A	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	Q1889C	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	Q1889D	Pathogenic	0.535
NOTCH3	Q9UM47-1.2	Q1889E	Neutral	0.056
NOTCH3	Q9UM47-1.2	Q1889F	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	Q1889G	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	Q1889H	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	Q1889I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	Q1889K	Neutral	0.203
NOTCH3	Q9UM47-1.2	Q1889L	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	Q1889M	Pathogenic	0.549
NOTCH3	Q9UM47-1.2	Q1889N	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	Q1889P	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	Q1889R	Neutral	0.195
NOTCH3	Q9UM47-1.2	Q1889S	Pathogenic	0.517
NOTCH3	Q9UM47-1.2	Q1889T	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	Q1889V	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	Q1889W	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	Q1889Y	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	I1890A	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	I1890C	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	I1890D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1890E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	I1890F	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	I1890G	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	I1890H	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	I1890K	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	I1890L	Neutral	0.132
NOTCH3	Q9UM47-1.2	I1890M	Neutral	0.411
NOTCH3	Q9UM47-1.2	I1890N	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1890P	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1890Q	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	I1890R	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1890S	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	I1890T	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	I1890V	Neutral	0.03
NOTCH3	Q9UM47-1.2	I1890W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1890Y	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	L1891A	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	L1891C	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	L1891D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1891E	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	L1891F	Neutral	0.396
NOTCH3	Q9UM47-1.2	L1891G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1891H	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	L1891I	Neutral	0.032
NOTCH3	Q9UM47-1.2	L1891K	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	L1891M	Neutral	0.032
NOTCH3	Q9UM47-1.2	L1891N	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1891P	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1891Q	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	L1891R	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	L1891S	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	L1891T	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	L1891V	Neutral	0.123
NOTCH3	Q9UM47-1.2	L1891W	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	L1891Y	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	I1892A	Pathogenic	0.862
NOTCH3	Q9UM47-1.2	I1892C	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	I1892D	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	I1892E	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	I1892F	Pathogenic	0.619
NOTCH3	Q9UM47-1.2	I1892G	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	I1892H	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	I1892K	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	I1892L	Neutral	0.076
NOTCH3	Q9UM47-1.2	I1892M	Neutral	0.272
NOTCH3	Q9UM47-1.2	I1892N	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	I1892P	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	I1892Q	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	I1892R	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	I1892S	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	I1892T	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	I1892V	Neutral	0.016
NOTCH3	Q9UM47-1.2	I1892W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	I1892Y	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	R1893A	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	R1893C	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1893D	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	R1893E	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	R1893F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1893G	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	R1893H	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	R1893I	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1893K	Neutral	0.07
NOTCH3	Q9UM47-1.2	R1893L	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	R1893M	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	R1893N	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	R1893P	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	R1893Q	Neutral	0.242
NOTCH3	Q9UM47-1.2	R1893S	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	R1893T	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	R1893V	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1893W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1893Y	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	N1894A	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	N1894C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N1894D	Neutral	0.145
NOTCH3	Q9UM47-1.2	N1894E	Neutral	0.428
NOTCH3	Q9UM47-1.2	N1894F	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N1894G	Neutral	0.396
NOTCH3	Q9UM47-1.2	N1894H	Neutral	0.138
NOTCH3	Q9UM47-1.2	N1894I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N1894K	Neutral	0.404
NOTCH3	Q9UM47-1.2	N1894L	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N1894M	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	N1894P	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	N1894Q	Neutral	0.424
NOTCH3	Q9UM47-1.2	N1894R	Neutral	0.392
NOTCH3	Q9UM47-1.2	N1894S	Neutral	0.137
NOTCH3	Q9UM47-1.2	N1894T	Neutral	0.439
NOTCH3	Q9UM47-1.2	N1894V	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N1894W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N1894Y	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	R1895A	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	R1895C	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1895D	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	R1895E	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	R1895F	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	R1895G	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	R1895H	Pathogenic	0.601
NOTCH3	Q9UM47-1.2	R1895I	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1895K	Neutral	0.071
NOTCH3	Q9UM47-1.2	R1895L	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	R1895M	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	R1895N	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	R1895P	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	R1895Q	Neutral	0.245
NOTCH3	Q9UM47-1.2	R1895S	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	R1895T	Pathogenic	0.862
NOTCH3	Q9UM47-1.2	R1895V	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1895W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	R1895Y	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	S1896A	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1896C	Neutral	0.039
NOTCH3	Q9UM47-1.2	S1896D	Neutral	0.009
NOTCH3	Q9UM47-1.2	S1896E	Neutral	0.008
NOTCH3	Q9UM47-1.2	S1896F	Neutral	0.132
NOTCH3	Q9UM47-1.2	S1896G	Neutral	0.008
NOTCH3	Q9UM47-1.2	S1896H	Neutral	0.034
NOTCH3	Q9UM47-1.2	S1896I	Neutral	0.137
NOTCH3	Q9UM47-1.2	S1896K	Neutral	0.007
NOTCH3	Q9UM47-1.2	S1896L	Neutral	0.137
NOTCH3	Q9UM47-1.2	S1896M	Neutral	0.034
NOTCH3	Q9UM47-1.2	S1896N	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1896P	Neutral	0.038
NOTCH3	Q9UM47-1.2	S1896Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	S1896R	Neutral	0.031
NOTCH3	Q9UM47-1.2	S1896T	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1896V	Neutral	0.146
NOTCH3	Q9UM47-1.2	S1896W	Neutral	0.385
NOTCH3	Q9UM47-1.2	S1896Y	Neutral	0.129
NOTCH3	Q9UM47-1.2	T1897A	Neutral	0.466
NOTCH3	Q9UM47-1.2	T1897C	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	T1897D	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	T1897E	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	T1897F	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	T1897G	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	T1897H	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	T1897I	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	T1897K	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	T1897L	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	T1897M	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	T1897N	Neutral	0.49
NOTCH3	Q9UM47-1.2	T1897P	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	T1897Q	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	T1897R	Pathogenic	0.782
NOTCH3	Q9UM47-1.2	T1897S	Neutral	0.165
NOTCH3	Q9UM47-1.2	T1897V	Neutral	0.482
NOTCH3	Q9UM47-1.2	T1897W	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	T1897Y	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	D1898A	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	D1898C	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	D1898E	Neutral	0.014
NOTCH3	Q9UM47-1.2	D1898F	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	D1898G	Pathogenic	0.556
NOTCH3	Q9UM47-1.2	D1898H	Pathogenic	0.571
NOTCH3	Q9UM47-1.2	D1898I	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	D1898K	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	D1898L	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	D1898M	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	D1898N	Neutral	0.065
NOTCH3	Q9UM47-1.2	D1898P	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	D1898Q	Neutral	0.229
NOTCH3	Q9UM47-1.2	D1898R	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	D1898S	Neutral	0.232
NOTCH3	Q9UM47-1.2	D1898T	Pathogenic	0.595
NOTCH3	Q9UM47-1.2	D1898V	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	D1898W	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	D1898Y	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	L1899A	Pathogenic	0.722
NOTCH3	Q9UM47-1.2	L1899C	Pathogenic	0.736
NOTCH3	Q9UM47-1.2	L1899D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1899E	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	L1899F	Neutral	0.403
NOTCH3	Q9UM47-1.2	L1899G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1899H	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	L1899I	Neutral	0.033
NOTCH3	Q9UM47-1.2	L1899K	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	L1899M	Neutral	0.033
NOTCH3	Q9UM47-1.2	L1899N	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	L1899P	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1899Q	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	L1899R	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	L1899S	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	L1899T	Pathogenic	0.742
NOTCH3	Q9UM47-1.2	L1899V	Neutral	0.126
NOTCH3	Q9UM47-1.2	L1899W	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	L1899Y	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	D1900A	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	D1900C	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	D1900E	Neutral	0.021
NOTCH3	Q9UM47-1.2	D1900F	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	D1900G	Pathogenic	0.654
NOTCH3	Q9UM47-1.2	D1900H	Pathogenic	0.668
NOTCH3	Q9UM47-1.2	D1900I	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	D1900K	Pathogenic	0.652
NOTCH3	Q9UM47-1.2	D1900L	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D1900M	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	D1900N	Neutral	0.095
NOTCH3	Q9UM47-1.2	D1900P	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	D1900Q	Neutral	0.309
NOTCH3	Q9UM47-1.2	D1900R	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	D1900S	Neutral	0.314
NOTCH3	Q9UM47-1.2	D1900T	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	D1900V	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	D1900W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	D1900Y	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	A1901C	Neutral	0.287
NOTCH3	Q9UM47-1.2	A1901D	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	A1901E	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	A1901F	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	A1901G	Neutral	0.287
NOTCH3	Q9UM47-1.2	A1901H	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	A1901I	Pathogenic	0.615
NOTCH3	Q9UM47-1.2	A1901K	Pathogenic	0.604
NOTCH3	Q9UM47-1.2	A1901L	Pathogenic	0.615
NOTCH3	Q9UM47-1.2	A1901M	Pathogenic	0.614
NOTCH3	Q9UM47-1.2	A1901N	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	A1901P	Pathogenic	0.643
NOTCH3	Q9UM47-1.2	A1901Q	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	A1901R	Pathogenic	0.592
NOTCH3	Q9UM47-1.2	A1901S	Neutral	0.085
NOTCH3	Q9UM47-1.2	A1901T	Neutral	0.281
NOTCH3	Q9UM47-1.2	A1901V	Neutral	0.273
NOTCH3	Q9UM47-1.2	A1901W	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	A1901Y	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	R1902A	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	R1902C	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1902D	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	R1902E	Pathogenic	0.586
NOTCH3	Q9UM47-1.2	R1902F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1902G	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	R1902H	Pathogenic	0.596
NOTCH3	Q9UM47-1.2	R1902I	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1902K	Neutral	0.07
NOTCH3	Q9UM47-1.2	R1902L	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	R1902M	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	R1902N	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	R1902P	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	R1902Q	Neutral	0.242
NOTCH3	Q9UM47-1.2	R1902S	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	R1902T	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	R1902V	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1902W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1902Y	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	M1903A	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	M1903C	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	M1903D	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	M1903E	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	M1903F	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	M1903G	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	M1903H	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	M1903I	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	M1903K	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	M1903L	Neutral	0.304
NOTCH3	Q9UM47-1.2	M1903N	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	M1903P	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	M1903Q	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	M1903R	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	M1903S	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	M1903T	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	M1903V	Pathogenic	0.648
NOTCH3	Q9UM47-1.2	M1903W	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	M1903Y	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	A1904C	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1904D	Neutral	0.095
NOTCH3	Q9UM47-1.2	A1904E	Neutral	0.021
NOTCH3	Q9UM47-1.2	A1904F	Neutral	0.081
NOTCH3	Q9UM47-1.2	A1904G	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1904H	Neutral	0.085
NOTCH3	Q9UM47-1.2	A1904I	Neutral	0.02
NOTCH3	Q9UM47-1.2	A1904K	Neutral	0.019
NOTCH3	Q9UM47-1.2	A1904L	Neutral	0.02
NOTCH3	Q9UM47-1.2	A1904M	Neutral	0.02
NOTCH3	Q9UM47-1.2	A1904N	Neutral	0.093
NOTCH3	Q9UM47-1.2	A1904P	Neutral	0.022
NOTCH3	Q9UM47-1.2	A1904Q	Neutral	0.02
NOTCH3	Q9UM47-1.2	A1904R	Neutral	0.018
NOTCH3	Q9UM47-1.2	A1904S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A1904T	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1904V	Neutral	0.005
NOTCH3	Q9UM47-1.2	A1904W	Neutral	0.266
NOTCH3	Q9UM47-1.2	A1904Y	Neutral	0.079
NOTCH3	Q9UM47-1.2	D1905A	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	D1905C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D1905E	Neutral	0.032
NOTCH3	Q9UM47-1.2	D1905F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1905G	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	D1905H	Pathogenic	0.753
NOTCH3	Q9UM47-1.2	D1905I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1905K	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	D1905L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1905M	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1905N	Neutral	0.137
NOTCH3	Q9UM47-1.2	D1905P	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	D1905Q	Neutral	0.404
NOTCH3	Q9UM47-1.2	D1905R	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	D1905S	Neutral	0.409
NOTCH3	Q9UM47-1.2	D1905T	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	D1905V	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1905W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1905Y	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	G1906A	Neutral	0.243
NOTCH3	Q9UM47-1.2	G1906C	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	G1906D	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	G1906E	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	G1906F	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1906H	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	G1906I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1906K	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	G1906L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1906M	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G1906N	Neutral	0.224
NOTCH3	Q9UM47-1.2	G1906P	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	G1906Q	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G1906R	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	G1906S	Neutral	0.239
NOTCH3	Q9UM47-1.2	G1906T	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	G1906V	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G1906W	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G1906Y	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	S1907A	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1907C	Neutral	0.094
NOTCH3	Q9UM47-1.2	S1907D	Neutral	0.022
NOTCH3	Q9UM47-1.2	S1907E	Neutral	0.02
NOTCH3	Q9UM47-1.2	S1907F	Neutral	0.282
NOTCH3	Q9UM47-1.2	S1907G	Neutral	0.021
NOTCH3	Q9UM47-1.2	S1907H	Neutral	0.083
NOTCH3	Q9UM47-1.2	S1907I	Neutral	0.291
NOTCH3	Q9UM47-1.2	S1907K	Neutral	0.018
NOTCH3	Q9UM47-1.2	S1907L	Neutral	0.291
NOTCH3	Q9UM47-1.2	S1907M	Neutral	0.082
NOTCH3	Q9UM47-1.2	S1907N	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1907P	Neutral	0.092
NOTCH3	Q9UM47-1.2	S1907Q	Neutral	0.02
NOTCH3	Q9UM47-1.2	S1907R	Neutral	0.075
NOTCH3	Q9UM47-1.2	S1907T	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1907V	Neutral	0.305
NOTCH3	Q9UM47-1.2	S1907W	Pathogenic	0.617
NOTCH3	Q9UM47-1.2	S1907Y	Neutral	0.276
NOTCH3	Q9UM47-1.2	T1908A	Neutral	0.455
NOTCH3	Q9UM47-1.2	T1908C	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	T1908D	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	T1908E	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	T1908F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	T1908G	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	T1908H	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	T1908I	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	T1908K	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	T1908L	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	T1908M	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	T1908N	Neutral	0.478
NOTCH3	Q9UM47-1.2	T1908P	Pathogenic	0.806
NOTCH3	Q9UM47-1.2	T1908Q	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	T1908R	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	T1908S	Neutral	0.158
NOTCH3	Q9UM47-1.2	T1908V	Neutral	0.47
NOTCH3	Q9UM47-1.2	T1908W	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	T1908Y	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	A1909C	Neutral	0.027
NOTCH3	Q9UM47-1.2	A1909D	Neutral	0.358
NOTCH3	Q9UM47-1.2	A1909E	Neutral	0.102
NOTCH3	Q9UM47-1.2	A1909F	Neutral	0.321
NOTCH3	Q9UM47-1.2	A1909G	Neutral	0.027
NOTCH3	Q9UM47-1.2	A1909H	Neutral	0.333
NOTCH3	Q9UM47-1.2	A1909I	Neutral	0.098
NOTCH3	Q9UM47-1.2	A1909K	Neutral	0.094
NOTCH3	Q9UM47-1.2	A1909L	Neutral	0.098
NOTCH3	Q9UM47-1.2	A1909M	Neutral	0.097
NOTCH3	Q9UM47-1.2	A1909N	Neutral	0.353
NOTCH3	Q9UM47-1.2	A1909P	Neutral	0.109
NOTCH3	Q9UM47-1.2	A1909Q	Neutral	0.1
NOTCH3	Q9UM47-1.2	A1909R	Neutral	0.09
NOTCH3	Q9UM47-1.2	A1909S	Neutral	0.006
NOTCH3	Q9UM47-1.2	A1909T	Neutral	0.026
NOTCH3	Q9UM47-1.2	A1909V	Neutral	0.025
NOTCH3	Q9UM47-1.2	A1909W	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	A1909Y	Neutral	0.314
NOTCH3	Q9UM47-1.2	L1910A	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	L1910C	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	L1910D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1910E	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	L1910F	Neutral	0.396
NOTCH3	Q9UM47-1.2	L1910G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1910H	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	L1910I	Neutral	0.032
NOTCH3	Q9UM47-1.2	L1910K	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	L1910M	Neutral	0.032
NOTCH3	Q9UM47-1.2	L1910N	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1910P	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1910Q	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	L1910R	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	L1910S	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	L1910T	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	L1910V	Neutral	0.123
NOTCH3	Q9UM47-1.2	L1910W	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	L1910Y	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	I1911A	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	I1911C	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	I1911D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1911E	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1911F	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	I1911G	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	I1911H	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1911K	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1911L	Neutral	0.125
NOTCH3	Q9UM47-1.2	I1911M	Neutral	0.394
NOTCH3	Q9UM47-1.2	I1911N	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1911P	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1911Q	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1911R	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1911S	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	I1911T	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	I1911V	Neutral	0.028
NOTCH3	Q9UM47-1.2	I1911W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1911Y	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	L1912A	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	L1912C	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	L1912D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1912E	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	L1912F	Neutral	0.396
NOTCH3	Q9UM47-1.2	L1912G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1912H	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	L1912I	Neutral	0.032
NOTCH3	Q9UM47-1.2	L1912K	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	L1912M	Neutral	0.032
NOTCH3	Q9UM47-1.2	L1912N	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1912P	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1912Q	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	L1912R	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	L1912S	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	L1912T	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	L1912V	Neutral	0.123
NOTCH3	Q9UM47-1.2	L1912W	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	L1912Y	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	A1913C	Neutral	0.402
NOTCH3	Q9UM47-1.2	A1913D	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	A1913E	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	A1913F	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	A1913G	Neutral	0.401
NOTCH3	Q9UM47-1.2	A1913H	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	A1913I	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	A1913K	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	A1913L	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	A1913M	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	A1913N	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	A1913P	Pathogenic	0.75
NOTCH3	Q9UM47-1.2	A1913Q	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	A1913R	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	A1913S	Neutral	0.134
NOTCH3	Q9UM47-1.2	A1913T	Neutral	0.394
NOTCH3	Q9UM47-1.2	A1913V	Neutral	0.385
NOTCH3	Q9UM47-1.2	A1913W	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	A1913Y	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	A1914C	Neutral	0.398
NOTCH3	Q9UM47-1.2	A1914D	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	A1914E	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	A1914F	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	A1914G	Neutral	0.397
NOTCH3	Q9UM47-1.2	A1914H	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	A1914I	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	A1914K	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	A1914L	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	A1914M	Pathogenic	0.722
NOTCH3	Q9UM47-1.2	A1914N	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	A1914P	Pathogenic	0.747
NOTCH3	Q9UM47-1.2	A1914Q	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	A1914R	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	A1914S	Neutral	0.132
NOTCH3	Q9UM47-1.2	A1914T	Neutral	0.39
NOTCH3	Q9UM47-1.2	A1914V	Neutral	0.381
NOTCH3	Q9UM47-1.2	A1914W	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	A1914Y	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	R1915A	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	R1915C	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1915D	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	R1915E	Pathogenic	0.586
NOTCH3	Q9UM47-1.2	R1915F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1915G	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	R1915H	Pathogenic	0.595
NOTCH3	Q9UM47-1.2	R1915I	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1915K	Neutral	0.07
NOTCH3	Q9UM47-1.2	R1915L	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	R1915M	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	R1915N	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	R1915P	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	R1915Q	Neutral	0.241
NOTCH3	Q9UM47-1.2	R1915S	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	R1915T	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	R1915V	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1915W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R1915Y	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	L1916A	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	L1916C	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	L1916D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1916E	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	L1916F	Neutral	0.391
NOTCH3	Q9UM47-1.2	L1916G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1916H	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	L1916I	Neutral	0.031
NOTCH3	Q9UM47-1.2	L1916K	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	L1916M	Neutral	0.031
NOTCH3	Q9UM47-1.2	L1916N	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1916P	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1916Q	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	L1916R	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	L1916S	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	L1916T	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	L1916V	Neutral	0.121
NOTCH3	Q9UM47-1.2	L1916W	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	L1916Y	Pathogenic	0.742
NOTCH3	Q9UM47-1.2	A1917C	Neutral	0.409
NOTCH3	Q9UM47-1.2	A1917D	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	A1917E	Pathogenic	0.743
NOTCH3	Q9UM47-1.2	A1917F	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	A1917G	Neutral	0.408
NOTCH3	Q9UM47-1.2	A1917H	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	A1917I	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	A1917K	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	A1917L	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	A1917M	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	A1917N	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	A1917P	Pathogenic	0.756
NOTCH3	Q9UM47-1.2	A1917Q	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	A1917R	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	A1917S	Neutral	0.137
NOTCH3	Q9UM47-1.2	A1917T	Neutral	0.401
NOTCH3	Q9UM47-1.2	A1917V	Neutral	0.392
NOTCH3	Q9UM47-1.2	A1917W	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	A1917Y	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	V1918A	Neutral	0.37
NOTCH3	Q9UM47-1.2	V1918C	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	V1918D	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	V1918E	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	V1918F	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	V1918G	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	V1918H	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	V1918I	Neutral	0.007
NOTCH3	Q9UM47-1.2	V1918K	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	V1918L	Neutral	0.122
NOTCH3	Q9UM47-1.2	V1918M	Neutral	0.121
NOTCH3	Q9UM47-1.2	V1918N	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	V1918P	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	V1918Q	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	V1918R	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	V1918S	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	V1918T	Neutral	0.394
NOTCH3	Q9UM47-1.2	V1918W	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	V1918Y	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	E1919A	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	E1919C	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	E1919D	Neutral	0.043
NOTCH3	Q9UM47-1.2	E1919F	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E1919G	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	E1919H	Neutral	0.49
NOTCH3	Q9UM47-1.2	E1919I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E1919K	Neutral	0.165
NOTCH3	Q9UM47-1.2	E1919L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	E1919M	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	E1919N	Neutral	0.485
NOTCH3	Q9UM47-1.2	E1919P	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	E1919Q	Neutral	0.045
NOTCH3	Q9UM47-1.2	E1919R	Neutral	0.46
NOTCH3	Q9UM47-1.2	E1919S	Neutral	0.464
NOTCH3	Q9UM47-1.2	E1919T	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	E1919V	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	E1919W	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	E1919Y	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	G1920A	Neutral	0.239
NOTCH3	Q9UM47-1.2	G1920C	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	G1920D	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	G1920E	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G1920F	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1920H	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	G1920I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1920K	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G1920L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1920M	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G1920N	Neutral	0.22
NOTCH3	Q9UM47-1.2	G1920P	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	G1920Q	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	G1920R	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	G1920S	Neutral	0.235
NOTCH3	Q9UM47-1.2	G1920T	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	G1920V	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	G1920W	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	G1920Y	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	M1921A	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	M1921C	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	M1921D	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	M1921E	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	M1921F	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	M1921G	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	M1921H	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	M1921I	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	M1921K	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	M1921L	Neutral	0.299
NOTCH3	Q9UM47-1.2	M1921N	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	M1921P	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	M1921Q	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	M1921R	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	M1921S	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	M1921T	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	M1921V	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	M1921W	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	M1921Y	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	V1922A	Neutral	0.266
NOTCH3	Q9UM47-1.2	V1922C	Pathogenic	0.638
NOTCH3	Q9UM47-1.2	V1922D	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	V1922E	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	V1922F	Pathogenic	0.629
NOTCH3	Q9UM47-1.2	V1922G	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	V1922H	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	V1922I	Neutral	0.004
NOTCH3	Q9UM47-1.2	V1922K	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	V1922L	Neutral	0.078
NOTCH3	Q9UM47-1.2	V1922M	Neutral	0.078
NOTCH3	Q9UM47-1.2	V1922N	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	V1922P	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	V1922Q	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	V1922R	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	V1922S	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	V1922T	Neutral	0.286
NOTCH3	Q9UM47-1.2	V1922W	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	V1922Y	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	E1923A	Neutral	0.49
NOTCH3	Q9UM47-1.2	E1923C	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	E1923D	Neutral	0.011
NOTCH3	Q9UM47-1.2	E1923F	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	E1923G	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	E1923H	Neutral	0.193
NOTCH3	Q9UM47-1.2	E1923I	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	E1923K	Neutral	0.047
NOTCH3	Q9UM47-1.2	E1923L	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	E1923M	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	E1923N	Neutral	0.19
NOTCH3	Q9UM47-1.2	E1923P	Pathogenic	0.513
NOTCH3	Q9UM47-1.2	E1923Q	Neutral	0.012
NOTCH3	Q9UM47-1.2	E1923R	Neutral	0.175
NOTCH3	Q9UM47-1.2	E1923S	Neutral	0.177
NOTCH3	Q9UM47-1.2	E1923T	Pathogenic	0.515
NOTCH3	Q9UM47-1.2	E1923V	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	E1923W	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	E1923Y	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	E1924A	Pathogenic	0.511
NOTCH3	Q9UM47-1.2	E1924C	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	E1924D	Neutral	0.012
NOTCH3	Q9UM47-1.2	E1924F	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	E1924G	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	E1924H	Neutral	0.207
NOTCH3	Q9UM47-1.2	E1924I	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	E1924K	Neutral	0.051
NOTCH3	Q9UM47-1.2	E1924L	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	E1924M	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	E1924N	Neutral	0.203
NOTCH3	Q9UM47-1.2	E1924P	Pathogenic	0.534
NOTCH3	Q9UM47-1.2	E1924Q	Neutral	0.013
NOTCH3	Q9UM47-1.2	E1924R	Neutral	0.188
NOTCH3	Q9UM47-1.2	E1924S	Neutral	0.19
NOTCH3	Q9UM47-1.2	E1924T	Pathogenic	0.536
NOTCH3	Q9UM47-1.2	E1924V	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	E1924W	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	E1924Y	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	L1925A	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	L1925C	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	L1925D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1925E	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	L1925F	Neutral	0.396
NOTCH3	Q9UM47-1.2	L1925G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1925H	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	L1925I	Neutral	0.032
NOTCH3	Q9UM47-1.2	L1925K	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	L1925M	Neutral	0.032
NOTCH3	Q9UM47-1.2	L1925N	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1925P	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1925Q	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	L1925R	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	L1925S	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	L1925T	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	L1925V	Neutral	0.123
NOTCH3	Q9UM47-1.2	L1925W	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	L1925Y	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	I1926A	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	I1926C	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	I1926D	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I1926E	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1926F	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	I1926G	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	I1926H	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1926K	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1926L	Neutral	0.11
NOTCH3	Q9UM47-1.2	I1926M	Neutral	0.362
NOTCH3	Q9UM47-1.2	I1926N	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1926P	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I1926Q	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1926R	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I1926S	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	I1926T	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	I1926V	Neutral	0.025
NOTCH3	Q9UM47-1.2	I1926W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I1926Y	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	A1927C	Neutral	0.009
NOTCH3	Q9UM47-1.2	A1927D	Neutral	0.149
NOTCH3	Q9UM47-1.2	A1927E	Neutral	0.035
NOTCH3	Q9UM47-1.2	A1927F	Neutral	0.129
NOTCH3	Q9UM47-1.2	A1927G	Neutral	0.008
NOTCH3	Q9UM47-1.2	A1927H	Neutral	0.135
NOTCH3	Q9UM47-1.2	A1927I	Neutral	0.033
NOTCH3	Q9UM47-1.2	A1927K	Neutral	0.032
NOTCH3	Q9UM47-1.2	A1927L	Neutral	0.033
NOTCH3	Q9UM47-1.2	A1927M	Neutral	0.033
NOTCH3	Q9UM47-1.2	A1927N	Neutral	0.146
NOTCH3	Q9UM47-1.2	A1927P	Neutral	0.037
NOTCH3	Q9UM47-1.2	A1927Q	Neutral	0.034
NOTCH3	Q9UM47-1.2	A1927R	Neutral	0.03
NOTCH3	Q9UM47-1.2	A1927S	Neutral	0.002
NOTCH3	Q9UM47-1.2	A1927T	Neutral	0.008
NOTCH3	Q9UM47-1.2	A1927V	Neutral	0.008
NOTCH3	Q9UM47-1.2	A1927W	Neutral	0.378
NOTCH3	Q9UM47-1.2	A1927Y	Neutral	0.126
NOTCH3	Q9UM47-1.2	S1928A	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1928C	Neutral	0.103
NOTCH3	Q9UM47-1.2	S1928D	Neutral	0.024
NOTCH3	Q9UM47-1.2	S1928E	Neutral	0.022
NOTCH3	Q9UM47-1.2	S1928F	Neutral	0.303
NOTCH3	Q9UM47-1.2	S1928G	Neutral	0.023
NOTCH3	Q9UM47-1.2	S1928H	Neutral	0.091
NOTCH3	Q9UM47-1.2	S1928I	Neutral	0.312
NOTCH3	Q9UM47-1.2	S1928K	Neutral	0.02
NOTCH3	Q9UM47-1.2	S1928L	Neutral	0.312
NOTCH3	Q9UM47-1.2	S1928M	Neutral	0.09
NOTCH3	Q9UM47-1.2	S1928N	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1928P	Neutral	0.101
NOTCH3	Q9UM47-1.2	S1928Q	Neutral	0.022
NOTCH3	Q9UM47-1.2	S1928R	Neutral	0.083
NOTCH3	Q9UM47-1.2	S1928T	Neutral	0.005
NOTCH3	Q9UM47-1.2	S1928V	Neutral	0.327
NOTCH3	Q9UM47-1.2	S1928W	Pathogenic	0.641
NOTCH3	Q9UM47-1.2	S1928Y	Neutral	0.297
NOTCH3	Q9UM47-1.2	H1929A	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	H1929C	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	H1929D	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	H1929E	Neutral	0.34
NOTCH3	Q9UM47-1.2	H1929F	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	H1929G	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	H1929I	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	H1929K	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	H1929L	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	H1929M	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	H1929N	Neutral	0.097
NOTCH3	Q9UM47-1.2	H1929P	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	H1929Q	Neutral	0.344
NOTCH3	Q9UM47-1.2	H1929R	Neutral	0.323
NOTCH3	Q9UM47-1.2	H1929S	Pathogenic	0.67
NOTCH3	Q9UM47-1.2	H1929T	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	H1929V	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	H1929W	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	H1929Y	Neutral	0.023
NOTCH3	Q9UM47-1.2	A1930C	Neutral	0.385
NOTCH3	Q9UM47-1.2	A1930D	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	A1930E	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	A1930F	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	A1930G	Neutral	0.384
NOTCH3	Q9UM47-1.2	A1930H	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	A1930I	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	A1930K	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	A1930L	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	A1930M	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	A1930N	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	A1930P	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	A1930Q	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	A1930R	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	A1930S	Neutral	0.126
NOTCH3	Q9UM47-1.2	A1930T	Neutral	0.378
NOTCH3	Q9UM47-1.2	A1930V	Neutral	0.368
NOTCH3	Q9UM47-1.2	A1930W	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	A1930Y	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	D1931A	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	D1931C	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	D1931E	Neutral	0.034
NOTCH3	Q9UM47-1.2	D1931F	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1931G	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	D1931H	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	D1931I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1931K	Pathogenic	0.753
NOTCH3	Q9UM47-1.2	D1931L	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	D1931M	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1931N	Neutral	0.146
NOTCH3	Q9UM47-1.2	D1931P	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	D1931Q	Neutral	0.421
NOTCH3	Q9UM47-1.2	D1931R	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	D1931S	Neutral	0.426
NOTCH3	Q9UM47-1.2	D1931T	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	D1931V	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D1931W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1931Y	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	V1932A	Neutral	0.285
NOTCH3	Q9UM47-1.2	V1932C	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	V1932D	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	V1932E	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	V1932F	Pathogenic	0.652
NOTCH3	Q9UM47-1.2	V1932G	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	V1932H	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	V1932I	Neutral	0.005
NOTCH3	Q9UM47-1.2	V1932K	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	V1932L	Neutral	0.086
NOTCH3	Q9UM47-1.2	V1932M	Neutral	0.086
NOTCH3	Q9UM47-1.2	V1932N	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	V1932P	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	V1932Q	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	V1932R	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	V1932S	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	V1932T	Neutral	0.306
NOTCH3	Q9UM47-1.2	V1932W	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	V1932Y	Pathogenic	0.646
NOTCH3	Q9UM47-1.2	N1933A	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	N1933C	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	N1933D	Neutral	0.153
NOTCH3	Q9UM47-1.2	N1933E	Neutral	0.443
NOTCH3	Q9UM47-1.2	N1933F	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N1933G	Neutral	0.411
NOTCH3	Q9UM47-1.2	N1933H	Neutral	0.145
NOTCH3	Q9UM47-1.2	N1933I	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N1933K	Neutral	0.419
NOTCH3	Q9UM47-1.2	N1933L	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N1933M	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	N1933P	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	N1933Q	Neutral	0.439
NOTCH3	Q9UM47-1.2	N1933R	Neutral	0.407
NOTCH3	Q9UM47-1.2	N1933S	Neutral	0.144
NOTCH3	Q9UM47-1.2	N1933T	Neutral	0.454
NOTCH3	Q9UM47-1.2	N1933V	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	N1933W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N1933Y	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	A1934C	Neutral	0.376
NOTCH3	Q9UM47-1.2	A1934D	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	A1934E	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	A1934F	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	A1934G	Neutral	0.376
NOTCH3	Q9UM47-1.2	A1934H	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	A1934I	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	A1934K	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	A1934L	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	A1934M	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	A1934N	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	A1934P	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	A1934Q	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	A1934R	Pathogenic	0.685
NOTCH3	Q9UM47-1.2	A1934S	Neutral	0.122
NOTCH3	Q9UM47-1.2	A1934T	Neutral	0.369
NOTCH3	Q9UM47-1.2	A1934V	Neutral	0.36
NOTCH3	Q9UM47-1.2	A1934W	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	A1934Y	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	V1935A	Neutral	0.249
NOTCH3	Q9UM47-1.2	V1935C	Pathogenic	0.617
NOTCH3	Q9UM47-1.2	V1935D	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	V1935E	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	V1935F	Pathogenic	0.608
NOTCH3	Q9UM47-1.2	V1935G	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	V1935H	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	V1935I	Neutral	0.004
NOTCH3	Q9UM47-1.2	V1935K	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	V1935L	Neutral	0.072
NOTCH3	Q9UM47-1.2	V1935M	Neutral	0.072
NOTCH3	Q9UM47-1.2	V1935N	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	V1935P	Pathogenic	0.882
NOTCH3	Q9UM47-1.2	V1935Q	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	V1935R	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	V1935S	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	V1935T	Neutral	0.268
NOTCH3	Q9UM47-1.2	V1935W	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	V1935Y	Pathogenic	0.602
NOTCH3	Q9UM47-1.2	D1936A	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	D1936C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D1936E	Neutral	0.034
NOTCH3	Q9UM47-1.2	D1936F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1936G	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	D1936H	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	D1936I	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1936K	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	D1936L	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	D1936M	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1936N	Neutral	0.143
NOTCH3	Q9UM47-1.2	D1936P	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	D1936Q	Neutral	0.416
NOTCH3	Q9UM47-1.2	D1936R	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	D1936S	Neutral	0.421
NOTCH3	Q9UM47-1.2	D1936T	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	D1936V	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D1936W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1936Y	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	E1937A	Neutral	0.122
NOTCH3	Q9UM47-1.2	E1937C	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	E1937D	Neutral	0.002
NOTCH3	Q9UM47-1.2	E1937F	Pathogenic	0.755
NOTCH3	Q9UM47-1.2	E1937G	Neutral	0.369
NOTCH3	Q9UM47-1.2	E1937H	Neutral	0.033
NOTCH3	Q9UM47-1.2	E1937I	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	E1937K	Neutral	0.007
NOTCH3	Q9UM47-1.2	E1937L	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	E1937M	Neutral	0.413
NOTCH3	Q9UM47-1.2	E1937N	Neutral	0.033
NOTCH3	Q9UM47-1.2	E1937P	Neutral	0.132
NOTCH3	Q9UM47-1.2	E1937Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	E1937R	Neutral	0.03
NOTCH3	Q9UM47-1.2	E1937S	Neutral	0.03
NOTCH3	Q9UM47-1.2	E1937T	Neutral	0.133
NOTCH3	Q9UM47-1.2	E1937V	Neutral	0.424
NOTCH3	Q9UM47-1.2	E1937W	Pathogenic	0.736
NOTCH3	Q9UM47-1.2	E1937Y	Neutral	0.397
NOTCH3	Q9UM47-1.2	L1938A	Neutral	0.121
NOTCH3	Q9UM47-1.2	L1938C	Neutral	0.128
NOTCH3	Q9UM47-1.2	L1938D	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	L1938E	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	L1938F	Neutral	0.034
NOTCH3	Q9UM47-1.2	L1938G	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	L1938H	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	L1938I	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1938K	Neutral	0.43
NOTCH3	Q9UM47-1.2	L1938M	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1938N	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	L1938P	Pathogenic	0.756
NOTCH3	Q9UM47-1.2	L1938Q	Neutral	0.429
NOTCH3	Q9UM47-1.2	L1938R	Neutral	0.418
NOTCH3	Q9UM47-1.2	L1938S	Neutral	0.391
NOTCH3	Q9UM47-1.2	L1938T	Neutral	0.132
NOTCH3	Q9UM47-1.2	L1938V	Neutral	0.008
NOTCH3	Q9UM47-1.2	L1938W	Neutral	0.399
NOTCH3	Q9UM47-1.2	L1938Y	Neutral	0.137
NOTCH3	Q9UM47-1.2	G1939A	Neutral	0.245
NOTCH3	Q9UM47-1.2	G1939C	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	G1939D	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	G1939E	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	G1939F	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	G1939H	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	G1939I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1939K	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	G1939L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	G1939M	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	G1939N	Neutral	0.225
NOTCH3	Q9UM47-1.2	G1939P	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	G1939Q	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	G1939R	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	G1939S	Neutral	0.24
NOTCH3	Q9UM47-1.2	G1939T	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	G1939V	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	G1939W	Pathogenic	0.825
NOTCH3	Q9UM47-1.2	G1939Y	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	K1940A	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	K1940C	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	K1940D	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	K1940E	Neutral	0.405
NOTCH3	Q9UM47-1.2	K1940F	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	K1940G	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	K1940H	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	K1940I	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	K1940L	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	K1940M	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	K1940N	Pathogenic	0.747
NOTCH3	Q9UM47-1.2	K1940P	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	K1940Q	Neutral	0.411
NOTCH3	Q9UM47-1.2	K1940R	Neutral	0.136
NOTCH3	Q9UM47-1.2	K1940S	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	K1940T	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	K1940V	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	K1940W	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	K1940Y	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	S1941A	Neutral	0.071
NOTCH3	Q9UM47-1.2	S1941C	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	S1941D	Neutral	0.249
NOTCH3	Q9UM47-1.2	S1941E	Neutral	0.236
NOTCH3	Q9UM47-1.2	S1941F	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	S1941G	Neutral	0.243
NOTCH3	Q9UM47-1.2	S1941H	Pathogenic	0.576
NOTCH3	Q9UM47-1.2	S1941I	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	S1941K	Neutral	0.219
NOTCH3	Q9UM47-1.2	S1941L	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	S1941M	Pathogenic	0.572
NOTCH3	Q9UM47-1.2	S1941N	Neutral	0.067
NOTCH3	Q9UM47-1.2	S1941P	Pathogenic	0.603
NOTCH3	Q9UM47-1.2	S1941Q	Neutral	0.232
NOTCH3	Q9UM47-1.2	S1941R	Pathogenic	0.549
NOTCH3	Q9UM47-1.2	S1941T	Neutral	0.067
NOTCH3	Q9UM47-1.2	S1941V	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	S1941W	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	S1941Y	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	A1942C	Neutral	0.401
NOTCH3	Q9UM47-1.2	A1942D	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	A1942E	Pathogenic	0.736
NOTCH3	Q9UM47-1.2	A1942F	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	A1942G	Neutral	0.4
NOTCH3	Q9UM47-1.2	A1942H	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	A1942I	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	A1942K	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	A1942L	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	A1942M	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	A1942N	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	A1942P	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	A1942Q	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	A1942R	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	A1942S	Neutral	0.133
NOTCH3	Q9UM47-1.2	A1942T	Neutral	0.393
NOTCH3	Q9UM47-1.2	A1942V	Neutral	0.384
NOTCH3	Q9UM47-1.2	A1942W	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	A1942Y	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	L1943A	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	L1943C	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	L1943D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1943E	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	L1943F	Neutral	0.394
NOTCH3	Q9UM47-1.2	L1943G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1943H	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	L1943I	Neutral	0.032
NOTCH3	Q9UM47-1.2	L1943K	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	L1943M	Neutral	0.032
NOTCH3	Q9UM47-1.2	L1943N	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1943P	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1943Q	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	L1943R	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	L1943S	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	L1943T	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	L1943V	Neutral	0.122
NOTCH3	Q9UM47-1.2	L1943W	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	L1943Y	Pathogenic	0.744
NOTCH3	Q9UM47-1.2	H1944A	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	H1944C	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1944D	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	H1944E	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	H1944F	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	H1944G	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	H1944I	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1944K	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	H1944L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1944M	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	H1944N	Neutral	0.36
NOTCH3	Q9UM47-1.2	H1944P	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	H1944Q	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	H1944R	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	H1944S	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	H1944T	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	H1944V	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H1944W	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	H1944Y	Neutral	0.109
NOTCH3	Q9UM47-1.2	W1945A	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1945C	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1945D	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1945E	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1945F	Pathogenic	0.861
NOTCH3	Q9UM47-1.2	W1945G	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1945H	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1945I	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1945K	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1945L	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1945M	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	W1945N	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1945P	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1945Q	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1945R	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1945S	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1945T	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W1945V	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W1945Y	Pathogenic	0.584
NOTCH3	Q9UM47-1.2	A1946C	Neutral	0.393
NOTCH3	Q9UM47-1.2	A1946D	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	A1946E	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	A1946F	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	A1946G	Neutral	0.392
NOTCH3	Q9UM47-1.2	A1946H	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	A1946I	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	A1946K	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	A1946L	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	A1946M	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	A1946N	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	A1946P	Pathogenic	0.743
NOTCH3	Q9UM47-1.2	A1946Q	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	A1946R	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	A1946S	Neutral	0.13
NOTCH3	Q9UM47-1.2	A1946T	Neutral	0.385
NOTCH3	Q9UM47-1.2	A1946V	Neutral	0.376
NOTCH3	Q9UM47-1.2	A1946W	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	A1946Y	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	A1947C	Neutral	0.362
NOTCH3	Q9UM47-1.2	A1947D	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	A1947E	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	A1947F	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	A1947G	Neutral	0.361
NOTCH3	Q9UM47-1.2	A1947H	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	A1947I	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	A1947K	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	A1947L	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	A1947M	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	A1947N	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	A1947P	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	A1947Q	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	A1947R	Pathogenic	0.671
NOTCH3	Q9UM47-1.2	A1947S	Neutral	0.115
NOTCH3	Q9UM47-1.2	A1947T	Neutral	0.354
NOTCH3	Q9UM47-1.2	A1947V	Neutral	0.345
NOTCH3	Q9UM47-1.2	A1947W	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	A1947Y	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	A1948C	Neutral	0.393
NOTCH3	Q9UM47-1.2	A1948D	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	A1948E	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	A1948F	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	A1948G	Neutral	0.392
NOTCH3	Q9UM47-1.2	A1948H	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	A1948I	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	A1948K	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	A1948L	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	A1948M	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	A1948N	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	A1948P	Pathogenic	0.743
NOTCH3	Q9UM47-1.2	A1948Q	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	A1948R	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	A1948S	Neutral	0.13
NOTCH3	Q9UM47-1.2	A1948T	Neutral	0.385
NOTCH3	Q9UM47-1.2	A1948V	Neutral	0.376
NOTCH3	Q9UM47-1.2	A1948W	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	A1948Y	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	V1949A	Pathogenic	0.503
NOTCH3	Q9UM47-1.2	V1949C	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	V1949D	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	V1949E	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	V1949F	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	V1949G	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	V1949H	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	V1949I	Neutral	0.011
NOTCH3	Q9UM47-1.2	V1949K	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	V1949L	Neutral	0.192
NOTCH3	Q9UM47-1.2	V1949M	Neutral	0.192
NOTCH3	Q9UM47-1.2	V1949N	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	V1949P	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	V1949Q	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	V1949R	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	V1949S	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	V1949T	Pathogenic	0.528
NOTCH3	Q9UM47-1.2	V1949W	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	V1949Y	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	N1950A	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	N1950C	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	N1950D	Neutral	0.148
NOTCH3	Q9UM47-1.2	N1950E	Neutral	0.433
NOTCH3	Q9UM47-1.2	N1950F	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N1950G	Neutral	0.401
NOTCH3	Q9UM47-1.2	N1950H	Neutral	0.14
NOTCH3	Q9UM47-1.2	N1950I	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N1950K	Neutral	0.409
NOTCH3	Q9UM47-1.2	N1950L	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N1950M	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	N1950P	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	N1950Q	Neutral	0.429
NOTCH3	Q9UM47-1.2	N1950R	Neutral	0.397
NOTCH3	Q9UM47-1.2	N1950S	Neutral	0.14
NOTCH3	Q9UM47-1.2	N1950T	Neutral	0.444
NOTCH3	Q9UM47-1.2	N1950V	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	N1950W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N1950Y	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	N1951A	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	N1951C	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	N1951D	Neutral	0.148
NOTCH3	Q9UM47-1.2	N1951E	Neutral	0.433
NOTCH3	Q9UM47-1.2	N1951F	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N1951G	Neutral	0.401
NOTCH3	Q9UM47-1.2	N1951H	Neutral	0.14
NOTCH3	Q9UM47-1.2	N1951I	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N1951K	Neutral	0.409
NOTCH3	Q9UM47-1.2	N1951L	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N1951M	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	N1951P	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	N1951Q	Neutral	0.429
NOTCH3	Q9UM47-1.2	N1951R	Neutral	0.397
NOTCH3	Q9UM47-1.2	N1951S	Neutral	0.14
NOTCH3	Q9UM47-1.2	N1951T	Neutral	0.444
NOTCH3	Q9UM47-1.2	N1951V	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	N1951W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N1951Y	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	V1952A	Neutral	0.416
NOTCH3	Q9UM47-1.2	V1952C	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	V1952D	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	V1952E	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	V1952F	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	V1952G	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	V1952H	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	V1952I	Neutral	0.008
NOTCH3	Q9UM47-1.2	V1952K	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	V1952L	Neutral	0.144
NOTCH3	Q9UM47-1.2	V1952M	Neutral	0.143
NOTCH3	Q9UM47-1.2	V1952N	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	V1952P	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	V1952Q	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	V1952R	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	V1952S	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	V1952T	Neutral	0.441
NOTCH3	Q9UM47-1.2	V1952W	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	V1952Y	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	E1953A	Pathogenic	0.534
NOTCH3	Q9UM47-1.2	E1953C	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	E1953D	Neutral	0.013
NOTCH3	Q9UM47-1.2	E1953F	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	E1953G	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	E1953H	Neutral	0.222
NOTCH3	Q9UM47-1.2	E1953I	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	E1953K	Neutral	0.055
NOTCH3	Q9UM47-1.2	E1953L	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	E1953M	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	E1953N	Neutral	0.218
NOTCH3	Q9UM47-1.2	E1953P	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	E1953Q	Neutral	0.014
NOTCH3	Q9UM47-1.2	E1953R	Neutral	0.202
NOTCH3	Q9UM47-1.2	E1953S	Neutral	0.204
NOTCH3	Q9UM47-1.2	E1953T	Pathogenic	0.559
NOTCH3	Q9UM47-1.2	E1953V	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	E1953W	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	E1953Y	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	A1954C	Neutral	0.393
NOTCH3	Q9UM47-1.2	A1954D	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	A1954E	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	A1954F	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	A1954G	Neutral	0.392
NOTCH3	Q9UM47-1.2	A1954H	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	A1954I	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	A1954K	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	A1954L	Pathogenic	0.719
NOTCH3	Q9UM47-1.2	A1954M	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	A1954N	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	A1954P	Pathogenic	0.743
NOTCH3	Q9UM47-1.2	A1954Q	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	A1954R	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	A1954S	Neutral	0.13
NOTCH3	Q9UM47-1.2	A1954T	Neutral	0.385
NOTCH3	Q9UM47-1.2	A1954V	Neutral	0.376
NOTCH3	Q9UM47-1.2	A1954W	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	A1954Y	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	T1955A	Neutral	0.097
NOTCH3	Q9UM47-1.2	T1955C	Neutral	0.345
NOTCH3	Q9UM47-1.2	T1955D	Neutral	0.35
NOTCH3	Q9UM47-1.2	T1955E	Neutral	0.337
NOTCH3	Q9UM47-1.2	T1955F	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	T1955G	Pathogenic	0.673
NOTCH3	Q9UM47-1.2	T1955H	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	T1955I	Neutral	0.326
NOTCH3	Q9UM47-1.2	T1955K	Neutral	0.316
NOTCH3	Q9UM47-1.2	T1955L	Neutral	0.326
NOTCH3	Q9UM47-1.2	T1955M	Neutral	0.325
NOTCH3	Q9UM47-1.2	T1955N	Neutral	0.105
NOTCH3	Q9UM47-1.2	T1955P	Neutral	0.348
NOTCH3	Q9UM47-1.2	T1955Q	Neutral	0.332
NOTCH3	Q9UM47-1.2	T1955R	Neutral	0.305
NOTCH3	Q9UM47-1.2	T1955S	Neutral	0.024
NOTCH3	Q9UM47-1.2	T1955V	Neutral	0.102
NOTCH3	Q9UM47-1.2	T1955W	Pathogenic	0.655
NOTCH3	Q9UM47-1.2	T1955Y	Pathogenic	0.672
NOTCH3	Q9UM47-1.2	L1956A	Neutral	0.126
NOTCH3	Q9UM47-1.2	L1956C	Neutral	0.133
NOTCH3	Q9UM47-1.2	L1956D	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	L1956E	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	L1956F	Neutral	0.036
NOTCH3	Q9UM47-1.2	L1956G	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	L1956H	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	L1956I	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1956K	Neutral	0.441
NOTCH3	Q9UM47-1.2	L1956M	Neutral	0.002
NOTCH3	Q9UM47-1.2	L1956N	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	L1956P	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	L1956Q	Neutral	0.441
NOTCH3	Q9UM47-1.2	L1956R	Neutral	0.429
NOTCH3	Q9UM47-1.2	L1956S	Neutral	0.402
NOTCH3	Q9UM47-1.2	L1956T	Neutral	0.137
NOTCH3	Q9UM47-1.2	L1956V	Neutral	0.008
NOTCH3	Q9UM47-1.2	L1956W	Neutral	0.411
NOTCH3	Q9UM47-1.2	L1956Y	Neutral	0.143
NOTCH3	Q9UM47-1.2	A1957C	Neutral	0.012
NOTCH3	Q9UM47-1.2	A1957D	Neutral	0.194
NOTCH3	Q9UM47-1.2	A1957E	Neutral	0.047
NOTCH3	Q9UM47-1.2	A1957F	Neutral	0.169
NOTCH3	Q9UM47-1.2	A1957G	Neutral	0.012
NOTCH3	Q9UM47-1.2	A1957H	Neutral	0.177
NOTCH3	Q9UM47-1.2	A1957I	Neutral	0.045
NOTCH3	Q9UM47-1.2	A1957K	Neutral	0.043
NOTCH3	Q9UM47-1.2	A1957L	Neutral	0.045
NOTCH3	Q9UM47-1.2	A1957M	Neutral	0.044
NOTCH3	Q9UM47-1.2	A1957N	Neutral	0.191
NOTCH3	Q9UM47-1.2	A1957P	Neutral	0.05
NOTCH3	Q9UM47-1.2	A1957Q	Neutral	0.046
NOTCH3	Q9UM47-1.2	A1957R	Neutral	0.041
NOTCH3	Q9UM47-1.2	A1957S	Neutral	0.003
NOTCH3	Q9UM47-1.2	A1957T	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1957V	Neutral	0.011
NOTCH3	Q9UM47-1.2	A1957W	Neutral	0.455
NOTCH3	Q9UM47-1.2	A1957Y	Neutral	0.165
NOTCH3	Q9UM47-1.2	L1958A	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	L1958C	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	L1958D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1958E	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1958F	Neutral	0.382
NOTCH3	Q9UM47-1.2	L1958G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1958H	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	L1958I	Neutral	0.03
NOTCH3	Q9UM47-1.2	L1958K	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	L1958M	Neutral	0.03
NOTCH3	Q9UM47-1.2	L1958N	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1958P	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1958Q	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	L1958R	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	L1958S	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	L1958T	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	L1958V	Neutral	0.117
NOTCH3	Q9UM47-1.2	L1958W	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	L1958Y	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	L1959A	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	L1959C	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	L1959D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L1959E	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	L1959F	Neutral	0.382
NOTCH3	Q9UM47-1.2	L1959G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1959H	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	L1959I	Neutral	0.03
NOTCH3	Q9UM47-1.2	L1959K	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	L1959M	Neutral	0.03
NOTCH3	Q9UM47-1.2	L1959N	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1959P	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1959Q	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	L1959R	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	L1959S	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	L1959T	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	L1959V	Neutral	0.117
NOTCH3	Q9UM47-1.2	L1959W	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	L1959Y	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	K1960A	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	K1960C	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	K1960D	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	K1960E	Neutral	0.226
NOTCH3	Q9UM47-1.2	K1960F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	K1960G	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	K1960H	Pathogenic	0.863
NOTCH3	Q9UM47-1.2	K1960I	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	K1960L	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	K1960M	Pathogenic	0.867
NOTCH3	Q9UM47-1.2	K1960N	Pathogenic	0.559
NOTCH3	Q9UM47-1.2	K1960P	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	K1960Q	Neutral	0.23
NOTCH3	Q9UM47-1.2	K1960R	Neutral	0.063
NOTCH3	Q9UM47-1.2	K1960S	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	K1960T	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	K1960V	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	K1960W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	K1960Y	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	N1961A	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	N1961C	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	N1961D	Neutral	0.086
NOTCH3	Q9UM47-1.2	N1961E	Neutral	0.293
NOTCH3	Q9UM47-1.2	N1961F	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	N1961G	Neutral	0.267
NOTCH3	Q9UM47-1.2	N1961H	Neutral	0.081
NOTCH3	Q9UM47-1.2	N1961I	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	N1961K	Neutral	0.273
NOTCH3	Q9UM47-1.2	N1961L	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	N1961M	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	N1961P	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	N1961Q	Neutral	0.29
NOTCH3	Q9UM47-1.2	N1961R	Neutral	0.264
NOTCH3	Q9UM47-1.2	N1961S	Neutral	0.081
NOTCH3	Q9UM47-1.2	N1961T	Neutral	0.303
NOTCH3	Q9UM47-1.2	N1961V	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	N1961W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	N1961Y	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	G1962A	Neutral	0.184
NOTCH3	Q9UM47-1.2	G1962C	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	G1962D	Neutral	0.484
NOTCH3	Q9UM47-1.2	G1962E	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	G1962F	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	G1962H	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	G1962I	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	G1962K	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	G1962L	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	G1962M	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	G1962N	Neutral	0.168
NOTCH3	Q9UM47-1.2	G1962P	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	G1962Q	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	G1962R	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	G1962S	Neutral	0.18
NOTCH3	Q9UM47-1.2	G1962T	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	G1962V	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	G1962W	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	G1962Y	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	A1963C	Neutral	0.373
NOTCH3	Q9UM47-1.2	A1963D	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	A1963E	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	A1963F	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	A1963G	Neutral	0.373
NOTCH3	Q9UM47-1.2	A1963H	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	A1963I	Pathogenic	0.702
NOTCH3	Q9UM47-1.2	A1963K	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	A1963L	Pathogenic	0.702
NOTCH3	Q9UM47-1.2	A1963M	Pathogenic	0.701
NOTCH3	Q9UM47-1.2	A1963N	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	A1963P	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	A1963Q	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	A1963R	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	A1963S	Neutral	0.121
NOTCH3	Q9UM47-1.2	A1963T	Neutral	0.366
NOTCH3	Q9UM47-1.2	A1963V	Neutral	0.357
NOTCH3	Q9UM47-1.2	A1963W	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	A1963Y	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	N1964A	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	N1964C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N1964D	Neutral	0.146
NOTCH3	Q9UM47-1.2	N1964E	Neutral	0.43
NOTCH3	Q9UM47-1.2	N1964F	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N1964G	Neutral	0.398
NOTCH3	Q9UM47-1.2	N1964H	Neutral	0.139
NOTCH3	Q9UM47-1.2	N1964I	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N1964K	Neutral	0.406
NOTCH3	Q9UM47-1.2	N1964L	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	N1964M	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	N1964P	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	N1964Q	Neutral	0.426
NOTCH3	Q9UM47-1.2	N1964R	Neutral	0.394
NOTCH3	Q9UM47-1.2	N1964S	Neutral	0.138
NOTCH3	Q9UM47-1.2	N1964T	Neutral	0.441
NOTCH3	Q9UM47-1.2	N1964V	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	N1964W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N1964Y	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	K1965A	Pathogenic	0.686
NOTCH3	Q9UM47-1.2	K1965C	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	K1965D	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	K1965E	Neutral	0.11
NOTCH3	Q9UM47-1.2	K1965F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	K1965G	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	K1965H	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	K1965I	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	K1965L	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	K1965M	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	K1965N	Neutral	0.348
NOTCH3	Q9UM47-1.2	K1965P	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	K1965Q	Neutral	0.112
NOTCH3	Q9UM47-1.2	K1965R	Neutral	0.028
NOTCH3	Q9UM47-1.2	K1965S	Neutral	0.329
NOTCH3	Q9UM47-1.2	K1965T	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	K1965V	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	K1965W	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	K1965Y	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	D1966A	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	D1966C	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D1966E	Neutral	0.032
NOTCH3	Q9UM47-1.2	D1966F	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1966G	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	D1966H	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	D1966I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1966K	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	D1966L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1966M	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1966N	Neutral	0.137
NOTCH3	Q9UM47-1.2	D1966P	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	D1966Q	Neutral	0.403
NOTCH3	Q9UM47-1.2	D1966R	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	D1966S	Neutral	0.408
NOTCH3	Q9UM47-1.2	D1966T	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	D1966V	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D1966W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D1966Y	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	M1967A	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	M1967C	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	M1967D	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	M1967E	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	M1967F	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	M1967G	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	M1967H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	M1967I	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	M1967K	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	M1967L	Neutral	0.182
NOTCH3	Q9UM47-1.2	M1967N	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	M1967P	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	M1967Q	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	M1967R	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	M1967S	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	M1967T	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	M1967V	Neutral	0.484
NOTCH3	Q9UM47-1.2	M1967W	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	M1967Y	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	Q1968A	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	Q1968C	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	Q1968D	Pathogenic	0.523
NOTCH3	Q9UM47-1.2	Q1968E	Neutral	0.054
NOTCH3	Q9UM47-1.2	Q1968F	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	Q1968G	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	Q1968H	Pathogenic	0.541
NOTCH3	Q9UM47-1.2	Q1968I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	Q1968K	Neutral	0.195
NOTCH3	Q9UM47-1.2	Q1968L	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	Q1968M	Pathogenic	0.537
NOTCH3	Q9UM47-1.2	Q1968N	Pathogenic	0.527
NOTCH3	Q9UM47-1.2	Q1968P	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	Q1968R	Neutral	0.188
NOTCH3	Q9UM47-1.2	Q1968S	Pathogenic	0.505
NOTCH3	Q9UM47-1.2	Q1968T	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	Q1968V	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	Q1968W	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	Q1968Y	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	D1969A	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	D1969C	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	D1969E	Neutral	0.008
NOTCH3	Q9UM47-1.2	D1969F	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	D1969G	Neutral	0.415
NOTCH3	Q9UM47-1.2	D1969H	Neutral	0.43
NOTCH3	Q9UM47-1.2	D1969I	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	D1969K	Neutral	0.413
NOTCH3	Q9UM47-1.2	D1969L	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	D1969M	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	D1969N	Neutral	0.038
NOTCH3	Q9UM47-1.2	D1969P	Neutral	0.456
NOTCH3	Q9UM47-1.2	D1969Q	Neutral	0.144
NOTCH3	Q9UM47-1.2	D1969R	Pathogenic	0.753
NOTCH3	Q9UM47-1.2	D1969S	Neutral	0.146
NOTCH3	Q9UM47-1.2	D1969T	Neutral	0.454
NOTCH3	Q9UM47-1.2	D1969V	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	D1969W	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D1969Y	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	S1970A	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1970C	Neutral	0.033
NOTCH3	Q9UM47-1.2	S1970D	Neutral	0.007
NOTCH3	Q9UM47-1.2	S1970E	Neutral	0.007
NOTCH3	Q9UM47-1.2	S1970F	Neutral	0.115
NOTCH3	Q9UM47-1.2	S1970G	Neutral	0.007
NOTCH3	Q9UM47-1.2	S1970H	Neutral	0.029
NOTCH3	Q9UM47-1.2	S1970I	Neutral	0.119
NOTCH3	Q9UM47-1.2	S1970K	Neutral	0.006
NOTCH3	Q9UM47-1.2	S1970L	Neutral	0.119
NOTCH3	Q9UM47-1.2	S1970M	Neutral	0.029
NOTCH3	Q9UM47-1.2	S1970N	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1970P	Neutral	0.033
NOTCH3	Q9UM47-1.2	S1970Q	Neutral	0.007
NOTCH3	Q9UM47-1.2	S1970R	Neutral	0.026
NOTCH3	Q9UM47-1.2	S1970T	Neutral	0.002
NOTCH3	Q9UM47-1.2	S1970V	Neutral	0.127
NOTCH3	Q9UM47-1.2	S1970W	Neutral	0.348
NOTCH3	Q9UM47-1.2	S1970Y	Neutral	0.112
NOTCH3	Q9UM47-1.2	K1971A	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	K1971C	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	K1971D	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	K1971E	Neutral	0.374
NOTCH3	Q9UM47-1.2	K1971F	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	K1971G	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	K1971H	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	K1971I	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	K1971L	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	K1971M	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	K1971N	Pathogenic	0.721
NOTCH3	Q9UM47-1.2	K1971P	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	K1971Q	Neutral	0.379
NOTCH3	Q9UM47-1.2	K1971R	Neutral	0.121
NOTCH3	Q9UM47-1.2	K1971S	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	K1971T	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	K1971V	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	K1971W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	K1971Y	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	E1972A	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	E1972C	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	E1972D	Neutral	0.023
NOTCH3	Q9UM47-1.2	E1972F	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	E1972G	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	E1972H	Neutral	0.333
NOTCH3	Q9UM47-1.2	E1972I	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	E1972K	Neutral	0.093
NOTCH3	Q9UM47-1.2	E1972L	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	E1972M	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	E1972N	Neutral	0.328
NOTCH3	Q9UM47-1.2	E1972P	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	E1972Q	Neutral	0.024
NOTCH3	Q9UM47-1.2	E1972R	Neutral	0.307
NOTCH3	Q9UM47-1.2	E1972S	Neutral	0.31
NOTCH3	Q9UM47-1.2	E1972T	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	E1972V	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	E1972W	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	E1972Y	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	E1973A	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	E1973C	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	E1973D	Neutral	0.035
NOTCH3	Q9UM47-1.2	E1973F	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	E1973G	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	E1973H	Neutral	0.438
NOTCH3	Q9UM47-1.2	E1973I	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	E1973K	Neutral	0.138
NOTCH3	Q9UM47-1.2	E1973L	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	E1973M	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	E1973N	Neutral	0.433
NOTCH3	Q9UM47-1.2	E1973P	Pathogenic	0.774
NOTCH3	Q9UM47-1.2	E1973Q	Neutral	0.037
NOTCH3	Q9UM47-1.2	E1973R	Neutral	0.409
NOTCH3	Q9UM47-1.2	E1973S	Neutral	0.412
NOTCH3	Q9UM47-1.2	E1973T	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	E1973V	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	E1973W	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	E1973Y	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	T1974A	Neutral	0.401
NOTCH3	Q9UM47-1.2	T1974C	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	T1974D	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	T1974E	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	T1974F	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	T1974G	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	T1974H	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	T1974I	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	T1974K	Pathogenic	0.743
NOTCH3	Q9UM47-1.2	T1974L	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	T1974M	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	T1974N	Neutral	0.425
NOTCH3	Q9UM47-1.2	T1974P	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	T1974Q	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	T1974R	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	T1974S	Neutral	0.131
NOTCH3	Q9UM47-1.2	T1974V	Neutral	0.416
NOTCH3	Q9UM47-1.2	T1974W	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	T1974Y	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	P1975A	Pathogenic	0.636
NOTCH3	Q9UM47-1.2	P1975C	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	P1975D	Pathogenic	0.657
NOTCH3	Q9UM47-1.2	P1975E	Pathogenic	0.641
NOTCH3	Q9UM47-1.2	P1975F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	P1975G	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	P1975H	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	P1975I	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	P1975K	Pathogenic	0.618
NOTCH3	Q9UM47-1.2	P1975L	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	P1975M	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	P1975N	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	P1975Q	Pathogenic	0.636
NOTCH3	Q9UM47-1.2	P1975R	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	P1975S	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	P1975T	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	P1975V	Pathogenic	0.891
NOTCH3	Q9UM47-1.2	P1975W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	P1975Y	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	L1976A	Pathogenic	0.654
NOTCH3	Q9UM47-1.2	L1976C	Pathogenic	0.669
NOTCH3	Q9UM47-1.2	L1976D	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1976E	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	L1976F	Neutral	0.329
NOTCH3	Q9UM47-1.2	L1976G	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	L1976H	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	L1976I	Neutral	0.024
NOTCH3	Q9UM47-1.2	L1976K	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	L1976M	Neutral	0.024
NOTCH3	Q9UM47-1.2	L1976N	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	L1976P	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	L1976Q	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	L1976R	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	L1976S	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	L1976T	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	L1976V	Neutral	0.095
NOTCH3	Q9UM47-1.2	L1976W	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	L1976Y	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	F1977A	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	F1977C	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	F1977D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F1977E	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1977G	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F1977H	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	F1977I	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	F1977K	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1977L	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	F1977M	Pathogenic	0.764
NOTCH3	Q9UM47-1.2	F1977N	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	F1977P	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	F1977Q	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1977R	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	F1977S	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	F1977T	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	F1977V	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	F1977W	Neutral	0.399
NOTCH3	Q9UM47-1.2	F1977Y	Neutral	0.034
NOTCH3	Q9UM47-1.2	L1978A	Pathogenic	0.671
NOTCH3	Q9UM47-1.2	L1978C	Pathogenic	0.686
NOTCH3	Q9UM47-1.2	L1978D	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1978E	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	L1978F	Neutral	0.346
NOTCH3	Q9UM47-1.2	L1978G	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	L1978H	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L1978I	Neutral	0.026
NOTCH3	Q9UM47-1.2	L1978K	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	L1978M	Neutral	0.026
NOTCH3	Q9UM47-1.2	L1978N	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	L1978P	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	L1978Q	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	L1978R	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	L1978S	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	L1978T	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	L1978V	Neutral	0.102
NOTCH3	Q9UM47-1.2	L1978W	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	L1978Y	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	A1979C	Neutral	0.336
NOTCH3	Q9UM47-1.2	A1979D	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	A1979E	Pathogenic	0.679
NOTCH3	Q9UM47-1.2	A1979F	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	A1979G	Neutral	0.335
NOTCH3	Q9UM47-1.2	A1979H	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	A1979I	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	A1979K	Pathogenic	0.657
NOTCH3	Q9UM47-1.2	A1979L	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	A1979M	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	A1979N	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	A1979P	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	A1979Q	Pathogenic	0.674
NOTCH3	Q9UM47-1.2	A1979R	Pathogenic	0.646
NOTCH3	Q9UM47-1.2	A1979S	Neutral	0.104
NOTCH3	Q9UM47-1.2	A1979T	Neutral	0.329
NOTCH3	Q9UM47-1.2	A1979V	Neutral	0.32
NOTCH3	Q9UM47-1.2	A1979W	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	A1979Y	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	A1980C	Neutral	0.348
NOTCH3	Q9UM47-1.2	A1980D	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	A1980E	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	A1980F	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	A1980G	Neutral	0.347
NOTCH3	Q9UM47-1.2	A1980H	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	A1980I	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	A1980K	Pathogenic	0.669
NOTCH3	Q9UM47-1.2	A1980L	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	A1980M	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	A1980N	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	A1980P	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	A1980Q	Pathogenic	0.685
NOTCH3	Q9UM47-1.2	A1980R	Pathogenic	0.657
NOTCH3	Q9UM47-1.2	A1980S	Neutral	0.109
NOTCH3	Q9UM47-1.2	A1980T	Neutral	0.34
NOTCH3	Q9UM47-1.2	A1980V	Neutral	0.332
NOTCH3	Q9UM47-1.2	A1980W	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	A1980Y	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	R1981A	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	R1981C	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	R1981D	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	R1981E	Pathogenic	0.533
NOTCH3	Q9UM47-1.2	R1981F	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1981G	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	R1981H	Pathogenic	0.543
NOTCH3	Q9UM47-1.2	R1981I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	R1981K	Neutral	0.057
NOTCH3	Q9UM47-1.2	R1981L	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	R1981M	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	R1981N	Pathogenic	0.521
NOTCH3	Q9UM47-1.2	R1981P	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	R1981Q	Neutral	0.204
NOTCH3	Q9UM47-1.2	R1981S	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	R1981T	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	R1981V	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	R1981W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1981Y	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	E1982A	Pathogenic	0.775
NOTCH3	Q9UM47-1.2	E1982C	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	E1982D	Neutral	0.038
NOTCH3	Q9UM47-1.2	E1982F	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	E1982G	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	E1982H	Neutral	0.462
NOTCH3	Q9UM47-1.2	E1982I	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	E1982K	Neutral	0.15
NOTCH3	Q9UM47-1.2	E1982L	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	E1982M	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	E1982N	Neutral	0.457
NOTCH3	Q9UM47-1.2	E1982P	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	E1982Q	Neutral	0.04
NOTCH3	Q9UM47-1.2	E1982R	Neutral	0.432
NOTCH3	Q9UM47-1.2	E1982S	Neutral	0.436
NOTCH3	Q9UM47-1.2	E1982T	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	E1982V	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	E1982W	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	E1982Y	Pathogenic	0.942
NOTCH3	Q9UM47-1.2	G1983A	Neutral	0.21
NOTCH3	Q9UM47-1.2	G1983C	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	G1983D	Pathogenic	0.525
NOTCH3	Q9UM47-1.2	G1983E	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	G1983F	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	G1983H	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	G1983I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G1983K	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	G1983L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	G1983M	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	G1983N	Neutral	0.192
NOTCH3	Q9UM47-1.2	G1983P	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	G1983Q	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	G1983R	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	G1983S	Neutral	0.205
NOTCH3	Q9UM47-1.2	G1983T	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	G1983V	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	G1983W	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	G1983Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	S1984A	Neutral	0.094
NOTCH3	Q9UM47-1.2	S1984C	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	S1984D	Neutral	0.311
NOTCH3	Q9UM47-1.2	S1984E	Neutral	0.296
NOTCH3	Q9UM47-1.2	S1984F	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	S1984G	Neutral	0.304
NOTCH3	Q9UM47-1.2	S1984H	Pathogenic	0.648
NOTCH3	Q9UM47-1.2	S1984I	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	S1984K	Neutral	0.276
NOTCH3	Q9UM47-1.2	S1984L	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	S1984M	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	S1984N	Neutral	0.088
NOTCH3	Q9UM47-1.2	S1984P	Pathogenic	0.673
NOTCH3	Q9UM47-1.2	S1984Q	Neutral	0.291
NOTCH3	Q9UM47-1.2	S1984R	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	S1984T	Neutral	0.089
NOTCH3	Q9UM47-1.2	S1984V	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	S1984W	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	S1984Y	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	Y1985A	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	Y1985C	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	Y1985D	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	Y1985E	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	Y1985F	Neutral	0.008
NOTCH3	Q9UM47-1.2	Y1985G	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	Y1985H	Neutral	0.032
NOTCH3	Q9UM47-1.2	Y1985I	Pathogenic	0.761
NOTCH3	Q9UM47-1.2	Y1985K	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	Y1985L	Pathogenic	0.761
NOTCH3	Q9UM47-1.2	Y1985M	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	Y1985N	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	Y1985P	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	Y1985Q	Pathogenic	0.755
NOTCH3	Q9UM47-1.2	Y1985R	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	Y1985S	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	Y1985T	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	Y1985V	Pathogenic	0.747
NOTCH3	Q9UM47-1.2	Y1985W	Neutral	0.032
NOTCH3	Q9UM47-1.2	E1986A	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	E1986C	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	E1986D	Neutral	0.026
NOTCH3	Q9UM47-1.2	E1986F	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	E1986G	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	E1986H	Neutral	0.361
NOTCH3	Q9UM47-1.2	E1986I	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	E1986K	Neutral	0.104
NOTCH3	Q9UM47-1.2	E1986L	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	E1986M	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	E1986N	Neutral	0.356
NOTCH3	Q9UM47-1.2	E1986P	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	E1986Q	Neutral	0.027
NOTCH3	Q9UM47-1.2	E1986R	Neutral	0.334
NOTCH3	Q9UM47-1.2	E1986S	Neutral	0.337
NOTCH3	Q9UM47-1.2	E1986T	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	E1986V	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	E1986W	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	E1986Y	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	A1987C	Neutral	0.109
NOTCH3	Q9UM47-1.2	A1987D	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	A1987E	Neutral	0.338
NOTCH3	Q9UM47-1.2	A1987F	Pathogenic	0.679
NOTCH3	Q9UM47-1.2	A1987G	Neutral	0.109
NOTCH3	Q9UM47-1.2	A1987H	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	A1987I	Neutral	0.326
NOTCH3	Q9UM47-1.2	A1987K	Neutral	0.317
NOTCH3	Q9UM47-1.2	A1987L	Neutral	0.326
NOTCH3	Q9UM47-1.2	A1987M	Neutral	0.325
NOTCH3	Q9UM47-1.2	A1987N	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	A1987P	Neutral	0.354
NOTCH3	Q9UM47-1.2	A1987Q	Neutral	0.333
NOTCH3	Q9UM47-1.2	A1987R	Neutral	0.306
NOTCH3	Q9UM47-1.2	A1987S	Neutral	0.027
NOTCH3	Q9UM47-1.2	A1987T	Neutral	0.106
NOTCH3	Q9UM47-1.2	A1987V	Neutral	0.102
NOTCH3	Q9UM47-1.2	A1987W	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	A1987Y	Pathogenic	0.672
NOTCH3	Q9UM47-1.2	A1988C	Neutral	0.201
NOTCH3	Q9UM47-1.2	A1988D	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	A1988E	Pathogenic	0.513
NOTCH3	Q9UM47-1.2	A1988F	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	A1988G	Neutral	0.201
NOTCH3	Q9UM47-1.2	A1988H	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	A1988I	Neutral	0.5
NOTCH3	Q9UM47-1.2	A1988K	Neutral	0.489
NOTCH3	Q9UM47-1.2	A1988L	Neutral	0.499
NOTCH3	Q9UM47-1.2	A1988M	Neutral	0.498
NOTCH3	Q9UM47-1.2	A1988N	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	A1988P	Pathogenic	0.53
NOTCH3	Q9UM47-1.2	A1988Q	Pathogenic	0.507
NOTCH3	Q9UM47-1.2	A1988R	Neutral	0.476
NOTCH3	Q9UM47-1.2	A1988S	Neutral	0.055
NOTCH3	Q9UM47-1.2	A1988T	Neutral	0.196
NOTCH3	Q9UM47-1.2	A1988V	Neutral	0.19
NOTCH3	Q9UM47-1.2	A1988W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	A1988Y	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	K1989A	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	K1989C	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	K1989D	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	K1989E	Neutral	0.228
NOTCH3	Q9UM47-1.2	K1989F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	K1989G	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	K1989H	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	K1989I	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	K1989L	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	K1989M	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	K1989N	Pathogenic	0.562
NOTCH3	Q9UM47-1.2	K1989P	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	K1989Q	Neutral	0.232
NOTCH3	Q9UM47-1.2	K1989R	Neutral	0.064
NOTCH3	Q9UM47-1.2	K1989S	Pathogenic	0.541
NOTCH3	Q9UM47-1.2	K1989T	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	K1989V	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	K1989W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	K1989Y	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	L1990A	Neutral	0.019
NOTCH3	Q9UM47-1.2	L1990C	Neutral	0.02
NOTCH3	Q9UM47-1.2	L1990D	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	L1990E	Neutral	0.319
NOTCH3	Q9UM47-1.2	L1990F	Neutral	0.005
NOTCH3	Q9UM47-1.2	L1990G	Pathogenic	0.626
NOTCH3	Q9UM47-1.2	L1990H	Neutral	0.325
NOTCH3	Q9UM47-1.2	L1990I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1990K	Neutral	0.095
NOTCH3	Q9UM47-1.2	L1990M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L1990N	Neutral	0.308
NOTCH3	Q9UM47-1.2	L1990P	Neutral	0.301
NOTCH3	Q9UM47-1.2	L1990Q	Neutral	0.095
NOTCH3	Q9UM47-1.2	L1990R	Neutral	0.091
NOTCH3	Q9UM47-1.2	L1990S	Neutral	0.082
NOTCH3	Q9UM47-1.2	L1990T	Neutral	0.021
NOTCH3	Q9UM47-1.2	L1990V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L1990W	Neutral	0.085
NOTCH3	Q9UM47-1.2	L1990Y	Neutral	0.022
NOTCH3	Q9UM47-1.2	L1991A	Pathogenic	0.662
NOTCH3	Q9UM47-1.2	L1991C	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	L1991D	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1991E	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	L1991F	Neutral	0.337
NOTCH3	Q9UM47-1.2	L1991G	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	L1991H	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	L1991I	Neutral	0.025
NOTCH3	Q9UM47-1.2	L1991K	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	L1991M	Neutral	0.025
NOTCH3	Q9UM47-1.2	L1991N	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	L1991P	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	L1991Q	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	L1991R	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	L1991S	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	L1991T	Pathogenic	0.685
NOTCH3	Q9UM47-1.2	L1991V	Neutral	0.098
NOTCH3	Q9UM47-1.2	L1991W	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	L1991Y	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	L1992A	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	L1992C	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	L1992D	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1992E	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L1992F	Neutral	0.353
NOTCH3	Q9UM47-1.2	L1992G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L1992H	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L1992I	Neutral	0.027
NOTCH3	Q9UM47-1.2	L1992K	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	L1992M	Neutral	0.027
NOTCH3	Q9UM47-1.2	L1992N	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	L1992P	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	L1992Q	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	L1992R	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	L1992S	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	L1992T	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	L1992V	Neutral	0.105
NOTCH3	Q9UM47-1.2	L1992W	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	L1992Y	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	D1993A	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	D1993C	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	D1993E	Neutral	0.012
NOTCH3	Q9UM47-1.2	D1993F	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	D1993G	Pathogenic	0.521
NOTCH3	Q9UM47-1.2	D1993H	Pathogenic	0.537
NOTCH3	Q9UM47-1.2	D1993I	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	D1993K	Pathogenic	0.519
NOTCH3	Q9UM47-1.2	D1993L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	D1993M	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	D1993N	Neutral	0.057
NOTCH3	Q9UM47-1.2	D1993P	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	D1993Q	Neutral	0.205
NOTCH3	Q9UM47-1.2	D1993R	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	D1993S	Neutral	0.208
NOTCH3	Q9UM47-1.2	D1993T	Pathogenic	0.561
NOTCH3	Q9UM47-1.2	D1993V	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	D1993W	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	D1993Y	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	H1994A	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	H1994C	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	H1994D	Pathogenic	0.843
NOTCH3	Q9UM47-1.2	H1994E	Pathogenic	0.558
NOTCH3	Q9UM47-1.2	H1994F	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	H1994G	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	H1994I	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	H1994K	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	H1994L	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	H1994M	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	H1994N	Neutral	0.209
NOTCH3	Q9UM47-1.2	H1994P	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	H1994Q	Pathogenic	0.562
NOTCH3	Q9UM47-1.2	H1994R	Pathogenic	0.539
NOTCH3	Q9UM47-1.2	H1994S	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	H1994T	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	H1994V	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	H1994W	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	H1994Y	Neutral	0.055
NOTCH3	Q9UM47-1.2	F1995A	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	F1995C	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	F1995D	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	F1995E	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	F1995G	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	F1995H	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	F1995I	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	F1995K	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	F1995L	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	F1995M	Pathogenic	0.608
NOTCH3	Q9UM47-1.2	F1995N	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	F1995P	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	F1995Q	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	F1995R	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	F1995S	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	F1995T	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	F1995V	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	F1995W	Neutral	0.242
NOTCH3	Q9UM47-1.2	F1995Y	Neutral	0.017
NOTCH3	Q9UM47-1.2	A1996C	Neutral	0.256
NOTCH3	Q9UM47-1.2	A1996D	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	A1996E	Pathogenic	0.59
NOTCH3	Q9UM47-1.2	A1996F	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	A1996G	Neutral	0.256
NOTCH3	Q9UM47-1.2	A1996H	Pathogenic	0.863
NOTCH3	Q9UM47-1.2	A1996I	Pathogenic	0.577
NOTCH3	Q9UM47-1.2	A1996K	Pathogenic	0.566
NOTCH3	Q9UM47-1.2	A1996L	Pathogenic	0.577
NOTCH3	Q9UM47-1.2	A1996M	Pathogenic	0.576
NOTCH3	Q9UM47-1.2	A1996N	Pathogenic	0.873
NOTCH3	Q9UM47-1.2	A1996P	Pathogenic	0.607
NOTCH3	Q9UM47-1.2	A1996Q	Pathogenic	0.585
NOTCH3	Q9UM47-1.2	A1996R	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	A1996S	Neutral	0.074
NOTCH3	Q9UM47-1.2	A1996T	Neutral	0.25
NOTCH3	Q9UM47-1.2	A1996V	Neutral	0.243
NOTCH3	Q9UM47-1.2	A1996W	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	A1996Y	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	N1997A	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	N1997C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N1997D	Neutral	0.132
NOTCH3	Q9UM47-1.2	N1997E	Neutral	0.401
NOTCH3	Q9UM47-1.2	N1997F	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	N1997G	Neutral	0.37
NOTCH3	Q9UM47-1.2	N1997H	Neutral	0.125
NOTCH3	Q9UM47-1.2	N1997I	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N1997K	Neutral	0.378
NOTCH3	Q9UM47-1.2	N1997L	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	N1997M	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	N1997P	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	N1997Q	Neutral	0.397
NOTCH3	Q9UM47-1.2	N1997R	Neutral	0.366
NOTCH3	Q9UM47-1.2	N1997S	Neutral	0.124
NOTCH3	Q9UM47-1.2	N1997T	Neutral	0.412
NOTCH3	Q9UM47-1.2	N1997V	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	N1997W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	N1997Y	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	R1998A	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	R1998C	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	R1998D	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	R1998E	Pathogenic	0.544
NOTCH3	Q9UM47-1.2	R1998F	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1998G	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	R1998H	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	R1998I	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1998K	Neutral	0.06
NOTCH3	Q9UM47-1.2	R1998L	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	R1998M	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	R1998N	Pathogenic	0.531
NOTCH3	Q9UM47-1.2	R1998P	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	R1998Q	Neutral	0.211
NOTCH3	Q9UM47-1.2	R1998S	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	R1998T	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	R1998V	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	R1998W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R1998Y	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	E1999A	Neutral	0.255
NOTCH3	Q9UM47-1.2	E1999C	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	E1999D	Neutral	0.004
NOTCH3	Q9UM47-1.2	E1999F	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	E1999G	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	E1999H	Neutral	0.079
NOTCH3	Q9UM47-1.2	E1999I	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	E1999K	Neutral	0.017
NOTCH3	Q9UM47-1.2	E1999L	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	E1999M	Pathogenic	0.635
NOTCH3	Q9UM47-1.2	E1999N	Neutral	0.077
NOTCH3	Q9UM47-1.2	E1999P	Neutral	0.273
NOTCH3	Q9UM47-1.2	E1999Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	E1999R	Neutral	0.07
NOTCH3	Q9UM47-1.2	E1999S	Neutral	0.071
NOTCH3	Q9UM47-1.2	E1999T	Neutral	0.274
NOTCH3	Q9UM47-1.2	E1999V	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	E1999W	Pathogenic	0.873
NOTCH3	Q9UM47-1.2	E1999Y	Pathogenic	0.619
NOTCH3	Q9UM47-1.2	I2000A	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	I2000C	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	I2000D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I2000E	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I2000F	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	I2000G	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	I2000H	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I2000K	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I2000L	Neutral	0.113
NOTCH3	Q9UM47-1.2	I2000M	Neutral	0.369
NOTCH3	Q9UM47-1.2	I2000N	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I2000P	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I2000Q	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I2000R	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I2000S	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	I2000T	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	I2000V	Neutral	0.026
NOTCH3	Q9UM47-1.2	I2000W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I2000Y	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	T2001A	Neutral	0.413
NOTCH3	Q9UM47-1.2	T2001C	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	T2001D	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	T2001E	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	T2001F	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	T2001G	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	T2001H	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	T2001I	Pathogenic	0.761
NOTCH3	Q9UM47-1.2	T2001K	Pathogenic	0.753
NOTCH3	Q9UM47-1.2	T2001L	Pathogenic	0.761
NOTCH3	Q9UM47-1.2	T2001M	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	T2001N	Neutral	0.436
NOTCH3	Q9UM47-1.2	T2001P	Pathogenic	0.778
NOTCH3	Q9UM47-1.2	T2001Q	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	T2001R	Pathogenic	0.743
NOTCH3	Q9UM47-1.2	T2001S	Neutral	0.137
NOTCH3	Q9UM47-1.2	T2001V	Neutral	0.428
NOTCH3	Q9UM47-1.2	T2001W	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	T2001Y	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	D2002A	Pathogenic	0.929
NOTCH3	Q9UM47-1.2	D2002C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	D2002E	Neutral	0.03
NOTCH3	Q9UM47-1.2	D2002F	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D2002G	Pathogenic	0.727
NOTCH3	Q9UM47-1.2	D2002H	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	D2002I	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D2002K	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	D2002L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D2002M	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D2002N	Neutral	0.129
NOTCH3	Q9UM47-1.2	D2002P	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	D2002Q	Neutral	0.387
NOTCH3	Q9UM47-1.2	D2002R	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	D2002S	Neutral	0.392
NOTCH3	Q9UM47-1.2	D2002T	Pathogenic	0.758
NOTCH3	Q9UM47-1.2	D2002V	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D2002W	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D2002Y	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	H2003A	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	H2003C	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	H2003D	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	H2003E	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	H2003F	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	H2003G	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	H2003I	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H2003K	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	H2003L	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	H2003M	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	H2003N	Neutral	0.325
NOTCH3	Q9UM47-1.2	H2003P	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	H2003Q	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	H2003R	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	H2003S	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	H2003T	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	H2003V	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	H2003W	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	H2003Y	Neutral	0.095
NOTCH3	Q9UM47-1.2	L2004A	Neutral	0.095
NOTCH3	Q9UM47-1.2	L2004C	Neutral	0.101
NOTCH3	Q9UM47-1.2	L2004D	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	L2004E	Pathogenic	0.721
NOTCH3	Q9UM47-1.2	L2004F	Neutral	0.027
NOTCH3	Q9UM47-1.2	L2004G	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	L2004H	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	L2004I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2004K	Neutral	0.366
NOTCH3	Q9UM47-1.2	L2004M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2004N	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	L2004P	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	L2004Q	Neutral	0.366
NOTCH3	Q9UM47-1.2	L2004R	Neutral	0.355
NOTCH3	Q9UM47-1.2	L2004S	Neutral	0.329
NOTCH3	Q9UM47-1.2	L2004T	Neutral	0.104
NOTCH3	Q9UM47-1.2	L2004V	Neutral	0.006
NOTCH3	Q9UM47-1.2	L2004W	Neutral	0.337
NOTCH3	Q9UM47-1.2	L2004Y	Neutral	0.109
NOTCH3	Q9UM47-1.2	D2005A	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	D2005C	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D2005E	Neutral	0.026
NOTCH3	Q9UM47-1.2	D2005F	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	D2005G	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	D2005H	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	D2005I	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	D2005K	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	D2005L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D2005M	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	D2005N	Neutral	0.114
NOTCH3	Q9UM47-1.2	D2005P	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	D2005Q	Neutral	0.354
NOTCH3	Q9UM47-1.2	D2005R	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	D2005S	Neutral	0.358
NOTCH3	Q9UM47-1.2	D2005T	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	D2005V	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D2005W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D2005Y	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	R2006A	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	R2006C	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	R2006D	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	R2006E	Neutral	0.471
NOTCH3	Q9UM47-1.2	R2006F	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	R2006G	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	R2006H	Neutral	0.481
NOTCH3	Q9UM47-1.2	R2006I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	R2006K	Neutral	0.045
NOTCH3	Q9UM47-1.2	R2006L	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	R2006M	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	R2006N	Neutral	0.459
NOTCH3	Q9UM47-1.2	R2006P	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	R2006Q	Neutral	0.167
NOTCH3	Q9UM47-1.2	R2006S	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	R2006T	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	R2006V	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	R2006W	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	R2006Y	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	L2007A	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	L2007C	Pathogenic	0.695
NOTCH3	Q9UM47-1.2	L2007D	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	L2007E	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L2007F	Neutral	0.356
NOTCH3	Q9UM47-1.2	L2007G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L2007H	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L2007I	Neutral	0.027
NOTCH3	Q9UM47-1.2	L2007K	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	L2007M	Neutral	0.027
NOTCH3	Q9UM47-1.2	L2007N	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	L2007P	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	L2007Q	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	L2007R	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	L2007S	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	L2007T	Pathogenic	0.702
NOTCH3	Q9UM47-1.2	L2007V	Neutral	0.106
NOTCH3	Q9UM47-1.2	L2007W	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	L2007Y	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	P2008A	Pathogenic	0.654
NOTCH3	Q9UM47-1.2	P2008C	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	P2008D	Pathogenic	0.675
NOTCH3	Q9UM47-1.2	P2008E	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	P2008F	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	P2008G	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	P2008H	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	P2008I	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	P2008K	Pathogenic	0.637
NOTCH3	Q9UM47-1.2	P2008L	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	P2008M	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	P2008N	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	P2008Q	Pathogenic	0.654
NOTCH3	Q9UM47-1.2	P2008R	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	P2008S	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	P2008T	Pathogenic	0.672
NOTCH3	Q9UM47-1.2	P2008V	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	P2008W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	P2008Y	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	R2009A	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	R2009C	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	R2009D	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	R2009E	Pathogenic	0.559
NOTCH3	Q9UM47-1.2	R2009F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R2009G	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	R2009H	Pathogenic	0.569
NOTCH3	Q9UM47-1.2	R2009I	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R2009K	Neutral	0.063
NOTCH3	Q9UM47-1.2	R2009L	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	R2009M	Pathogenic	0.861
NOTCH3	Q9UM47-1.2	R2009N	Pathogenic	0.547
NOTCH3	Q9UM47-1.2	R2009P	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	R2009Q	Neutral	0.222
NOTCH3	Q9UM47-1.2	R2009S	Pathogenic	0.835
NOTCH3	Q9UM47-1.2	R2009T	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	R2009V	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R2009W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	R2009Y	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	D2010A	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	D2010C	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D2010E	Neutral	0.027
NOTCH3	Q9UM47-1.2	D2010F	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	D2010G	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	D2010H	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	D2010I	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	D2010K	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	D2010L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D2010M	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	D2010N	Neutral	0.117
NOTCH3	Q9UM47-1.2	D2010P	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	D2010Q	Neutral	0.362
NOTCH3	Q9UM47-1.2	D2010R	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	D2010S	Neutral	0.366
NOTCH3	Q9UM47-1.2	D2010T	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	D2010V	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D2010W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D2010Y	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	V2011A	Neutral	0.086
NOTCH3	Q9UM47-1.2	V2011C	Neutral	0.315
NOTCH3	Q9UM47-1.2	V2011D	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	V2011E	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	V2011F	Neutral	0.306
NOTCH3	Q9UM47-1.2	V2011G	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	V2011H	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	V2011I	Neutral	0.001
NOTCH3	Q9UM47-1.2	V2011K	Pathogenic	0.671
NOTCH3	Q9UM47-1.2	V2011L	Neutral	0.022
NOTCH3	Q9UM47-1.2	V2011M	Neutral	0.022
NOTCH3	Q9UM47-1.2	V2011N	Pathogenic	0.909
NOTCH3	Q9UM47-1.2	V2011P	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	V2011Q	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	V2011R	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	V2011S	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	V2011T	Neutral	0.094
NOTCH3	Q9UM47-1.2	V2011W	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	V2011Y	Neutral	0.301
NOTCH3	Q9UM47-1.2	A2012C	Neutral	0.346
NOTCH3	Q9UM47-1.2	A2012D	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	A2012E	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	A2012F	Pathogenic	0.901
NOTCH3	Q9UM47-1.2	A2012G	Neutral	0.345
NOTCH3	Q9UM47-1.2	A2012H	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	A2012I	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	A2012K	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	A2012L	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	A2012M	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	A2012N	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	A2012P	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	A2012Q	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	A2012R	Pathogenic	0.656
NOTCH3	Q9UM47-1.2	A2012S	Neutral	0.109
NOTCH3	Q9UM47-1.2	A2012T	Neutral	0.339
NOTCH3	Q9UM47-1.2	A2012V	Neutral	0.33
NOTCH3	Q9UM47-1.2	A2012W	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	A2012Y	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	Q2013A	Neutral	0.477
NOTCH3	Q9UM47-1.2	Q2013C	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	Q2013D	Neutral	0.18
NOTCH3	Q9UM47-1.2	Q2013E	Neutral	0.011
NOTCH3	Q9UM47-1.2	Q2013F	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	Q2013G	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	Q2013H	Neutral	0.191
NOTCH3	Q9UM47-1.2	Q2013I	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	Q2013K	Neutral	0.046
NOTCH3	Q9UM47-1.2	Q2013L	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	Q2013M	Neutral	0.189
NOTCH3	Q9UM47-1.2	Q2013N	Neutral	0.183
NOTCH3	Q9UM47-1.2	Q2013P	Neutral	0.5
NOTCH3	Q9UM47-1.2	Q2013R	Neutral	0.044
NOTCH3	Q9UM47-1.2	Q2013S	Neutral	0.17
NOTCH3	Q9UM47-1.2	Q2013T	Pathogenic	0.502
NOTCH3	Q9UM47-1.2	Q2013V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	Q2013W	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	Q2013Y	Neutral	0.497
NOTCH3	Q9UM47-1.2	E2014A	Pathogenic	0.519
NOTCH3	Q9UM47-1.2	E2014C	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	E2014D	Neutral	0.012
NOTCH3	Q9UM47-1.2	E2014F	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	E2014G	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	E2014H	Neutral	0.212
NOTCH3	Q9UM47-1.2	E2014I	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	E2014K	Neutral	0.052
NOTCH3	Q9UM47-1.2	E2014L	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	E2014M	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	E2014N	Neutral	0.208
NOTCH3	Q9UM47-1.2	E2014P	Pathogenic	0.542
NOTCH3	Q9UM47-1.2	E2014Q	Neutral	0.013
NOTCH3	Q9UM47-1.2	E2014R	Neutral	0.192
NOTCH3	Q9UM47-1.2	E2014S	Neutral	0.195
NOTCH3	Q9UM47-1.2	E2014T	Pathogenic	0.543
NOTCH3	Q9UM47-1.2	E2014V	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	E2014W	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	E2014Y	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	R2015A	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	R2015C	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	R2015D	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	R2015E	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	R2015F	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R2015G	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	R2015H	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	R2015I	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R2015K	Neutral	0.062
NOTCH3	Q9UM47-1.2	R2015L	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	R2015M	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	R2015N	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	R2015P	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	R2015Q	Neutral	0.217
NOTCH3	Q9UM47-1.2	R2015S	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	R2015T	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	R2015V	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	R2015W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	R2015Y	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	L2016A	Neutral	0.064
NOTCH3	Q9UM47-1.2	L2016C	Neutral	0.068
NOTCH3	Q9UM47-1.2	L2016D	Pathogenic	0.878
NOTCH3	Q9UM47-1.2	L2016E	Pathogenic	0.628
NOTCH3	Q9UM47-1.2	L2016F	Neutral	0.018
NOTCH3	Q9UM47-1.2	L2016G	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	L2016H	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	L2016I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2016K	Neutral	0.274
NOTCH3	Q9UM47-1.2	L2016M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2016N	Pathogenic	0.616
NOTCH3	Q9UM47-1.2	L2016P	Pathogenic	0.608
NOTCH3	Q9UM47-1.2	L2016Q	Neutral	0.274
NOTCH3	Q9UM47-1.2	L2016R	Neutral	0.264
NOTCH3	Q9UM47-1.2	L2016S	Neutral	0.243
NOTCH3	Q9UM47-1.2	L2016T	Neutral	0.071
NOTCH3	Q9UM47-1.2	L2016V	Neutral	0.004
NOTCH3	Q9UM47-1.2	L2016W	Neutral	0.25
NOTCH3	Q9UM47-1.2	L2016Y	Neutral	0.074
NOTCH3	Q9UM47-1.2	H2017A	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	H2017C	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	H2017D	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	H2017E	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	H2017F	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	H2017G	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	H2017I	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H2017K	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	H2017L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H2017M	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	H2017N	Neutral	0.341
NOTCH3	Q9UM47-1.2	H2017P	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	H2017Q	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	H2017R	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	H2017S	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	H2017T	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	H2017V	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	H2017W	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	H2017Y	Neutral	0.102
NOTCH3	Q9UM47-1.2	Q2018A	Neutral	0.077
NOTCH3	Q9UM47-1.2	Q2018C	Pathogenic	0.65
NOTCH3	Q9UM47-1.2	Q2018D	Neutral	0.02
NOTCH3	Q9UM47-1.2	Q2018E	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q2018F	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	Q2018G	Neutral	0.259
NOTCH3	Q9UM47-1.2	Q2018H	Neutral	0.021
NOTCH3	Q9UM47-1.2	Q2018I	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	Q2018K	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q2018L	Neutral	0.306
NOTCH3	Q9UM47-1.2	Q2018M	Neutral	0.021
NOTCH3	Q9UM47-1.2	Q2018N	Neutral	0.02
NOTCH3	Q9UM47-1.2	Q2018P	Neutral	0.083
NOTCH3	Q9UM47-1.2	Q2018R	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q2018S	Neutral	0.018
NOTCH3	Q9UM47-1.2	Q2018T	Neutral	0.084
NOTCH3	Q9UM47-1.2	Q2018V	Neutral	0.306
NOTCH3	Q9UM47-1.2	Q2018W	Neutral	0.276
NOTCH3	Q9UM47-1.2	Q2018Y	Neutral	0.083
NOTCH3	Q9UM47-1.2	D2019A	Pathogenic	0.924
NOTCH3	Q9UM47-1.2	D2019C	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	D2019E	Neutral	0.028
NOTCH3	Q9UM47-1.2	D2019F	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	D2019G	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	D2019H	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	D2019I	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D2019K	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	D2019L	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	D2019M	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	D2019N	Neutral	0.121
NOTCH3	Q9UM47-1.2	D2019P	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	D2019Q	Neutral	0.37
NOTCH3	Q9UM47-1.2	D2019R	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	D2019S	Neutral	0.375
NOTCH3	Q9UM47-1.2	D2019T	Pathogenic	0.744
NOTCH3	Q9UM47-1.2	D2019V	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	D2019W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D2019Y	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	I2020A	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	I2020C	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	I2020D	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I2020E	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I2020F	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	I2020G	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	I2020H	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I2020K	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I2020L	Neutral	0.111
NOTCH3	Q9UM47-1.2	I2020M	Neutral	0.363
NOTCH3	Q9UM47-1.2	I2020N	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I2020P	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I2020Q	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I2020R	Pathogenic	0.996
NOTCH3	Q9UM47-1.2	I2020S	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	I2020T	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	I2020V	Neutral	0.025
NOTCH3	Q9UM47-1.2	I2020W	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	I2020Y	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	V2021A	Neutral	0.474
NOTCH3	Q9UM47-1.2	V2021C	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	V2021D	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	V2021E	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	V2021F	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	V2021G	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	V2021H	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	V2021I	Neutral	0.01
NOTCH3	Q9UM47-1.2	V2021K	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	V2021L	Neutral	0.175
NOTCH3	Q9UM47-1.2	V2021M	Neutral	0.175
NOTCH3	Q9UM47-1.2	V2021N	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	V2021P	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	V2021Q	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	V2021R	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	V2021S	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	V2021T	Neutral	0.499
NOTCH3	Q9UM47-1.2	V2021W	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	V2021Y	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	R2022A	Pathogenic	0.638
NOTCH3	Q9UM47-1.2	R2022C	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	R2022D	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	R2022E	Neutral	0.311
NOTCH3	Q9UM47-1.2	R2022F	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	R2022G	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	R2022H	Neutral	0.32
NOTCH3	Q9UM47-1.2	R2022I	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	R2022K	Neutral	0.023
NOTCH3	Q9UM47-1.2	R2022L	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	R2022M	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	R2022N	Neutral	0.3
NOTCH3	Q9UM47-1.2	R2022P	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	R2022Q	Neutral	0.092
NOTCH3	Q9UM47-1.2	R2022S	Pathogenic	0.643
NOTCH3	Q9UM47-1.2	R2022T	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	R2022V	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	R2022W	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	R2022Y	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	L2023A	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	L2023C	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	L2023D	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L2023E	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L2023F	Neutral	0.352
NOTCH3	Q9UM47-1.2	L2023G	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	L2023H	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	L2023I	Neutral	0.027
NOTCH3	Q9UM47-1.2	L2023K	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	L2023M	Neutral	0.027
NOTCH3	Q9UM47-1.2	L2023N	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	L2023P	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	L2023Q	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	L2023R	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	L2023S	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	L2023T	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	L2023V	Neutral	0.104
NOTCH3	Q9UM47-1.2	L2023W	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	L2023Y	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	L2024A	Pathogenic	0.595
NOTCH3	Q9UM47-1.2	L2024C	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	L2024D	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	L2024E	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	L2024F	Neutral	0.276
NOTCH3	Q9UM47-1.2	L2024G	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	L2024H	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	L2024I	Neutral	0.019
NOTCH3	Q9UM47-1.2	L2024K	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	L2024M	Neutral	0.019
NOTCH3	Q9UM47-1.2	L2024N	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	L2024P	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	L2024Q	Pathogenic	0.889
NOTCH3	Q9UM47-1.2	L2024R	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	L2024S	Pathogenic	0.873
NOTCH3	Q9UM47-1.2	L2024T	Pathogenic	0.619
NOTCH3	Q9UM47-1.2	L2024V	Neutral	0.075
NOTCH3	Q9UM47-1.2	L2024W	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	L2024Y	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	D2025A	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	D2025C	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	D2025E	Neutral	0.017
NOTCH3	Q9UM47-1.2	D2025F	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	D2025G	Pathogenic	0.601
NOTCH3	Q9UM47-1.2	D2025H	Pathogenic	0.616
NOTCH3	Q9UM47-1.2	D2025I	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	D2025K	Pathogenic	0.599
NOTCH3	Q9UM47-1.2	D2025L	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	D2025M	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	D2025N	Neutral	0.077
NOTCH3	Q9UM47-1.2	D2025P	Pathogenic	0.64
NOTCH3	Q9UM47-1.2	D2025Q	Neutral	0.263
NOTCH3	Q9UM47-1.2	D2025R	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	D2025S	Neutral	0.267
NOTCH3	Q9UM47-1.2	D2025T	Pathogenic	0.639
NOTCH3	Q9UM47-1.2	D2025V	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	D2025W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	D2025Y	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	Q2026A	Neutral	0.114
NOTCH3	Q9UM47-1.2	Q2026C	Pathogenic	0.742
NOTCH3	Q9UM47-1.2	Q2026D	Neutral	0.03
NOTCH3	Q9UM47-1.2	Q2026E	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q2026F	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	Q2026G	Neutral	0.351
NOTCH3	Q9UM47-1.2	Q2026H	Neutral	0.032
NOTCH3	Q9UM47-1.2	Q2026I	Pathogenic	0.756
NOTCH3	Q9UM47-1.2	Q2026K	Neutral	0.007
NOTCH3	Q9UM47-1.2	Q2026L	Neutral	0.405
NOTCH3	Q9UM47-1.2	Q2026M	Neutral	0.032
NOTCH3	Q9UM47-1.2	Q2026N	Neutral	0.03
NOTCH3	Q9UM47-1.2	Q2026P	Neutral	0.123
NOTCH3	Q9UM47-1.2	Q2026R	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q2026S	Neutral	0.028
NOTCH3	Q9UM47-1.2	Q2026T	Neutral	0.124
NOTCH3	Q9UM47-1.2	Q2026V	Neutral	0.405
NOTCH3	Q9UM47-1.2	Q2026W	Neutral	0.37
NOTCH3	Q9UM47-1.2	Q2026Y	Neutral	0.122
NOTCH3	Q9UM47-1.2	P2027A	Neutral	0.026
NOTCH3	Q9UM47-1.2	P2027C	Neutral	0.374
NOTCH3	Q9UM47-1.2	P2027D	Neutral	0.029
NOTCH3	Q9UM47-1.2	P2027E	Neutral	0.027
NOTCH3	Q9UM47-1.2	P2027F	Pathogenic	0.7
NOTCH3	Q9UM47-1.2	P2027G	Neutral	0.102
NOTCH3	Q9UM47-1.2	P2027H	Neutral	0.107
NOTCH3	Q9UM47-1.2	P2027I	Neutral	0.349
NOTCH3	Q9UM47-1.2	P2027K	Neutral	0.024
NOTCH3	Q9UM47-1.2	P2027L	Neutral	0.348
NOTCH3	Q9UM47-1.2	P2027M	Neutral	0.105
NOTCH3	Q9UM47-1.2	P2027N	Neutral	0.116
NOTCH3	Q9UM47-1.2	P2027Q	Neutral	0.026
NOTCH3	Q9UM47-1.2	P2027R	Neutral	0.097
NOTCH3	Q9UM47-1.2	P2027S	Neutral	0.027
NOTCH3	Q9UM47-1.2	P2027T	Neutral	0.028
NOTCH3	Q9UM47-1.2	P2027V	Neutral	0.112
NOTCH3	Q9UM47-1.2	P2027W	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	P2027Y	Neutral	0.332
NOTCH3	Q9UM47-1.2	S2028A	Neutral	0.003
NOTCH3	Q9UM47-1.2	S2028C	Neutral	0.052
NOTCH3	Q9UM47-1.2	S2028D	Neutral	0.012
NOTCH3	Q9UM47-1.2	S2028E	Neutral	0.011
NOTCH3	Q9UM47-1.2	S2028F	Neutral	0.172
NOTCH3	Q9UM47-1.2	S2028G	Neutral	0.011
NOTCH3	Q9UM47-1.2	S2028H	Neutral	0.046
NOTCH3	Q9UM47-1.2	S2028I	Neutral	0.178
NOTCH3	Q9UM47-1.2	S2028K	Neutral	0.01
NOTCH3	Q9UM47-1.2	S2028L	Neutral	0.178
NOTCH3	Q9UM47-1.2	S2028M	Neutral	0.045
NOTCH3	Q9UM47-1.2	S2028N	Neutral	0.003
NOTCH3	Q9UM47-1.2	S2028P	Neutral	0.051
NOTCH3	Q9UM47-1.2	S2028Q	Neutral	0.011
NOTCH3	Q9UM47-1.2	S2028R	Neutral	0.041
NOTCH3	Q9UM47-1.2	S2028T	Neutral	0.003
NOTCH3	Q9UM47-1.2	S2028V	Neutral	0.188
NOTCH3	Q9UM47-1.2	S2028W	Neutral	0.46
NOTCH3	Q9UM47-1.2	S2028Y	Neutral	0.168
NOTCH3	Q9UM47-1.2	G2029A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2029C	Neutral	0.15
NOTCH3	Q9UM47-1.2	G2029D	Neutral	0.008
NOTCH3	Q9UM47-1.2	G2029E	Neutral	0.034
NOTCH3	Q9UM47-1.2	G2029F	Neutral	0.128
NOTCH3	Q9UM47-1.2	G2029H	Neutral	0.033
NOTCH3	Q9UM47-1.2	G2029I	Neutral	0.411
NOTCH3	Q9UM47-1.2	G2029K	Neutral	0.031
NOTCH3	Q9UM47-1.2	G2029L	Neutral	0.411
NOTCH3	Q9UM47-1.2	G2029M	Neutral	0.132
NOTCH3	Q9UM47-1.2	G2029N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2029P	Neutral	0.037
NOTCH3	Q9UM47-1.2	G2029Q	Neutral	0.033
NOTCH3	Q9UM47-1.2	G2029R	Neutral	0.03
NOTCH3	Q9UM47-1.2	G2029S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2029T	Neutral	0.036
NOTCH3	Q9UM47-1.2	G2029V	Neutral	0.141
NOTCH3	Q9UM47-1.2	G2029W	Neutral	0.028
NOTCH3	Q9UM47-1.2	G2029Y	Neutral	0.125
NOTCH3	Q9UM47-1.2	P2030A	Neutral	0.029
NOTCH3	Q9UM47-1.2	P2030C	Neutral	0.402
NOTCH3	Q9UM47-1.2	P2030D	Neutral	0.032
NOTCH3	Q9UM47-1.2	P2030E	Neutral	0.03
NOTCH3	Q9UM47-1.2	P2030F	Pathogenic	0.725
NOTCH3	Q9UM47-1.2	P2030G	Neutral	0.114
NOTCH3	Q9UM47-1.2	P2030H	Neutral	0.119
NOTCH3	Q9UM47-1.2	P2030I	Neutral	0.376
NOTCH3	Q9UM47-1.2	P2030K	Neutral	0.027
NOTCH3	Q9UM47-1.2	P2030L	Neutral	0.376
NOTCH3	Q9UM47-1.2	P2030M	Neutral	0.117
NOTCH3	Q9UM47-1.2	P2030N	Neutral	0.129
NOTCH3	Q9UM47-1.2	P2030Q	Neutral	0.029
NOTCH3	Q9UM47-1.2	P2030R	Neutral	0.108
NOTCH3	Q9UM47-1.2	P2030S	Neutral	0.03
NOTCH3	Q9UM47-1.2	P2030T	Neutral	0.032
NOTCH3	Q9UM47-1.2	P2030V	Neutral	0.124
NOTCH3	Q9UM47-1.2	P2030W	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	P2030Y	Neutral	0.359
NOTCH3	Q9UM47-1.2	R2031A	Neutral	0.439
NOTCH3	Q9UM47-1.2	R2031C	Pathogenic	0.946
NOTCH3	Q9UM47-1.2	R2031D	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	R2031E	Neutral	0.167
NOTCH3	Q9UM47-1.2	R2031F	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	R2031G	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	R2031H	Neutral	0.173
NOTCH3	Q9UM47-1.2	R2031I	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	R2031K	Neutral	0.011
NOTCH3	Q9UM47-1.2	R2031L	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	R2031M	Neutral	0.496
NOTCH3	Q9UM47-1.2	R2031N	Neutral	0.16
NOTCH3	Q9UM47-1.2	R2031P	Pathogenic	0.796
NOTCH3	Q9UM47-1.2	R2031Q	Neutral	0.043
NOTCH3	Q9UM47-1.2	R2031S	Neutral	0.444
NOTCH3	Q9UM47-1.2	R2031T	Neutral	0.464
NOTCH3	Q9UM47-1.2	R2031V	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	R2031W	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	R2031Y	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	S2032A	Neutral	0.075
NOTCH3	Q9UM47-1.2	S2032C	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	S2032D	Neutral	0.261
NOTCH3	Q9UM47-1.2	S2032E	Neutral	0.248
NOTCH3	Q9UM47-1.2	S2032F	Pathogenic	0.862
NOTCH3	Q9UM47-1.2	S2032G	Neutral	0.255
NOTCH3	Q9UM47-1.2	S2032H	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	S2032I	Pathogenic	0.867
NOTCH3	Q9UM47-1.2	S2032K	Neutral	0.23
NOTCH3	Q9UM47-1.2	S2032L	Pathogenic	0.867
NOTCH3	Q9UM47-1.2	S2032M	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	S2032N	Neutral	0.071
NOTCH3	Q9UM47-1.2	S2032P	Pathogenic	0.618
NOTCH3	Q9UM47-1.2	S2032Q	Neutral	0.244
NOTCH3	Q9UM47-1.2	S2032R	Pathogenic	0.564
NOTCH3	Q9UM47-1.2	S2032T	Neutral	0.071
NOTCH3	Q9UM47-1.2	S2032V	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	S2032W	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	S2032Y	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	P2033A	Pathogenic	0.628
NOTCH3	Q9UM47-1.2	P2033C	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	P2033D	Pathogenic	0.649
NOTCH3	Q9UM47-1.2	P2033E	Pathogenic	0.633
NOTCH3	Q9UM47-1.2	P2033F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	P2033G	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	P2033H	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	P2033I	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	P2033K	Pathogenic	0.61
NOTCH3	Q9UM47-1.2	P2033L	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	P2033M	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	P2033N	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	P2033Q	Pathogenic	0.628
NOTCH3	Q9UM47-1.2	P2033R	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	P2033S	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	P2033T	Pathogenic	0.646
NOTCH3	Q9UM47-1.2	P2033V	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	P2033W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	P2033Y	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	P2034A	Neutral	0.082
NOTCH3	Q9UM47-1.2	P2034C	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	P2034D	Neutral	0.089
NOTCH3	Q9UM47-1.2	P2034E	Neutral	0.084
NOTCH3	Q9UM47-1.2	P2034F	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	P2034G	Neutral	0.275
NOTCH3	Q9UM47-1.2	P2034H	Neutral	0.285
NOTCH3	Q9UM47-1.2	P2034I	Pathogenic	0.641
NOTCH3	Q9UM47-1.2	P2034K	Neutral	0.077
NOTCH3	Q9UM47-1.2	P2034L	Pathogenic	0.641
NOTCH3	Q9UM47-1.2	P2034M	Neutral	0.281
NOTCH3	Q9UM47-1.2	P2034N	Neutral	0.304
NOTCH3	Q9UM47-1.2	P2034Q	Neutral	0.082
NOTCH3	Q9UM47-1.2	P2034R	Neutral	0.264
NOTCH3	Q9UM47-1.2	P2034S	Neutral	0.084
NOTCH3	Q9UM47-1.2	P2034T	Neutral	0.088
NOTCH3	Q9UM47-1.2	P2034V	Neutral	0.296
NOTCH3	Q9UM47-1.2	P2034W	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	P2034Y	Pathogenic	0.624
NOTCH3	Q9UM47-1.2	G2035A	Neutral	0.045
NOTCH3	Q9UM47-1.2	G2035C	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	G2035D	Neutral	0.165
NOTCH3	Q9UM47-1.2	G2035E	Neutral	0.455
NOTCH3	Q9UM47-1.2	G2035F	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	G2035H	Neutral	0.446
NOTCH3	Q9UM47-1.2	G2035I	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	G2035K	Neutral	0.431
NOTCH3	Q9UM47-1.2	G2035L	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	G2035M	Pathogenic	0.783
NOTCH3	Q9UM47-1.2	G2035N	Neutral	0.041
NOTCH3	Q9UM47-1.2	G2035P	Neutral	0.474
NOTCH3	Q9UM47-1.2	G2035Q	Neutral	0.45
NOTCH3	Q9UM47-1.2	G2035R	Neutral	0.419
NOTCH3	Q9UM47-1.2	G2035S	Neutral	0.044
NOTCH3	Q9UM47-1.2	G2035T	Neutral	0.47
NOTCH3	Q9UM47-1.2	G2035V	Pathogenic	0.795
NOTCH3	Q9UM47-1.2	G2035W	Neutral	0.407
NOTCH3	Q9UM47-1.2	G2035Y	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	P2036A	Neutral	0.05
NOTCH3	Q9UM47-1.2	P2036C	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	P2036D	Neutral	0.055
NOTCH3	Q9UM47-1.2	P2036E	Neutral	0.051
NOTCH3	Q9UM47-1.2	P2036F	Pathogenic	0.821
NOTCH3	Q9UM47-1.2	P2036G	Neutral	0.183
NOTCH3	Q9UM47-1.2	P2036H	Neutral	0.191
NOTCH3	Q9UM47-1.2	P2036I	Pathogenic	0.513
NOTCH3	Q9UM47-1.2	P2036K	Neutral	0.047
NOTCH3	Q9UM47-1.2	P2036L	Pathogenic	0.512
NOTCH3	Q9UM47-1.2	P2036M	Neutral	0.187
NOTCH3	Q9UM47-1.2	P2036N	Neutral	0.205
NOTCH3	Q9UM47-1.2	P2036Q	Neutral	0.05
NOTCH3	Q9UM47-1.2	P2036R	Neutral	0.175
NOTCH3	Q9UM47-1.2	P2036S	Neutral	0.051
NOTCH3	Q9UM47-1.2	P2036T	Neutral	0.054
NOTCH3	Q9UM47-1.2	P2036V	Neutral	0.198
NOTCH3	Q9UM47-1.2	P2036W	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	P2036Y	Neutral	0.495
NOTCH3	Q9UM47-1.2	H2037A	Neutral	0.308
NOTCH3	Q9UM47-1.2	H2037C	Pathogenic	0.686
NOTCH3	Q9UM47-1.2	H2037D	Neutral	0.097
NOTCH3	Q9UM47-1.2	H2037E	Neutral	0.025
NOTCH3	Q9UM47-1.2	H2037F	Neutral	0.101
NOTCH3	Q9UM47-1.2	H2037G	Neutral	0.292
NOTCH3	Q9UM47-1.2	H2037I	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	H2037K	Neutral	0.101
NOTCH3	Q9UM47-1.2	H2037L	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	H2037M	Neutral	0.347
NOTCH3	Q9UM47-1.2	H2037N	Neutral	0.005
NOTCH3	Q9UM47-1.2	H2037P	Neutral	0.327
NOTCH3	Q9UM47-1.2	H2037Q	Neutral	0.025
NOTCH3	Q9UM47-1.2	H2037R	Neutral	0.023
NOTCH3	Q9UM47-1.2	H2037S	Neutral	0.091
NOTCH3	Q9UM47-1.2	H2037T	Neutral	0.329
NOTCH3	Q9UM47-1.2	H2037V	Pathogenic	0.702
NOTCH3	Q9UM47-1.2	H2037W	Neutral	0.316
NOTCH3	Q9UM47-1.2	H2037Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	G2038A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2038C	Neutral	0.175
NOTCH3	Q9UM47-1.2	G2038D	Neutral	0.01
NOTCH3	Q9UM47-1.2	G2038E	Neutral	0.041
NOTCH3	Q9UM47-1.2	G2038F	Neutral	0.15
NOTCH3	Q9UM47-1.2	G2038H	Neutral	0.039
NOTCH3	Q9UM47-1.2	G2038I	Neutral	0.456
NOTCH3	Q9UM47-1.2	G2038K	Neutral	0.037
NOTCH3	Q9UM47-1.2	G2038L	Neutral	0.456
NOTCH3	Q9UM47-1.2	G2038M	Neutral	0.155
NOTCH3	Q9UM47-1.2	G2038N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2038P	Neutral	0.044
NOTCH3	Q9UM47-1.2	G2038Q	Neutral	0.04
NOTCH3	Q9UM47-1.2	G2038R	Neutral	0.035
NOTCH3	Q9UM47-1.2	G2038S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2038T	Neutral	0.043
NOTCH3	Q9UM47-1.2	G2038V	Neutral	0.165
NOTCH3	Q9UM47-1.2	G2038W	Neutral	0.034
NOTCH3	Q9UM47-1.2	G2038Y	Neutral	0.146
NOTCH3	Q9UM47-1.2	L2039A	Neutral	0.338
NOTCH3	Q9UM47-1.2	L2039C	Neutral	0.353
NOTCH3	Q9UM47-1.2	L2039D	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L2039E	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	L2039F	Neutral	0.117
NOTCH3	Q9UM47-1.2	L2039G	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	L2039H	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	L2039I	Neutral	0.007
NOTCH3	Q9UM47-1.2	L2039K	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	L2039M	Neutral	0.007
NOTCH3	Q9UM47-1.2	L2039N	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	L2039P	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	L2039Q	Pathogenic	0.737
NOTCH3	Q9UM47-1.2	L2039R	Pathogenic	0.728
NOTCH3	Q9UM47-1.2	L2039S	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	L2039T	Neutral	0.361
NOTCH3	Q9UM47-1.2	L2039V	Neutral	0.028
NOTCH3	Q9UM47-1.2	L2039W	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	L2039Y	Neutral	0.372
NOTCH3	Q9UM47-1.2	G2040A	Neutral	0.005
NOTCH3	Q9UM47-1.2	G2040C	Neutral	0.295
NOTCH3	Q9UM47-1.2	G2040D	Neutral	0.019
NOTCH3	Q9UM47-1.2	G2040E	Neutral	0.078
NOTCH3	Q9UM47-1.2	G2040F	Neutral	0.259
NOTCH3	Q9UM47-1.2	G2040H	Neutral	0.075
NOTCH3	Q9UM47-1.2	G2040I	Pathogenic	0.624
NOTCH3	Q9UM47-1.2	G2040K	Neutral	0.071
NOTCH3	Q9UM47-1.2	G2040L	Pathogenic	0.624
NOTCH3	Q9UM47-1.2	G2040M	Neutral	0.266
NOTCH3	Q9UM47-1.2	G2040N	Neutral	0.004
NOTCH3	Q9UM47-1.2	G2040P	Neutral	0.083
NOTCH3	Q9UM47-1.2	G2040Q	Neutral	0.076
NOTCH3	Q9UM47-1.2	G2040R	Neutral	0.068
NOTCH3	Q9UM47-1.2	G2040S	Neutral	0.005
NOTCH3	Q9UM47-1.2	G2040T	Neutral	0.082
NOTCH3	Q9UM47-1.2	G2040V	Neutral	0.281
NOTCH3	Q9UM47-1.2	G2040W	Neutral	0.065
NOTCH3	Q9UM47-1.2	G2040Y	Neutral	0.253
NOTCH3	Q9UM47-1.2	P2041A	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	P2041C	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	P2041D	Pathogenic	0.527
NOTCH3	Q9UM47-1.2	P2041E	Pathogenic	0.51
NOTCH3	Q9UM47-1.2	P2041F	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	P2041G	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	P2041H	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	P2041I	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	P2041K	Neutral	0.485
NOTCH3	Q9UM47-1.2	P2041L	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	P2041M	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	P2041N	Pathogenic	0.833
NOTCH3	Q9UM47-1.2	P2041Q	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	P2041R	Pathogenic	0.803
NOTCH3	Q9UM47-1.2	P2041S	Pathogenic	0.51
NOTCH3	Q9UM47-1.2	P2041T	Pathogenic	0.523
NOTCH3	Q9UM47-1.2	P2041V	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	P2041W	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	P2041Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	L2042A	Neutral	0.03
NOTCH3	Q9UM47-1.2	L2042C	Neutral	0.032
NOTCH3	Q9UM47-1.2	L2042D	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	L2042E	Neutral	0.43
NOTCH3	Q9UM47-1.2	L2042F	Neutral	0.008
NOTCH3	Q9UM47-1.2	L2042G	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	L2042H	Neutral	0.437
NOTCH3	Q9UM47-1.2	L2042I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2042K	Neutral	0.144
NOTCH3	Q9UM47-1.2	L2042M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2042N	Neutral	0.418
NOTCH3	Q9UM47-1.2	L2042P	Neutral	0.41
NOTCH3	Q9UM47-1.2	L2042Q	Neutral	0.144
NOTCH3	Q9UM47-1.2	L2042R	Neutral	0.138
NOTCH3	Q9UM47-1.2	L2042S	Neutral	0.126
NOTCH3	Q9UM47-1.2	L2042T	Neutral	0.033
NOTCH3	Q9UM47-1.2	L2042V	Neutral	0.002
NOTCH3	Q9UM47-1.2	L2042W	Neutral	0.13
NOTCH3	Q9UM47-1.2	L2042Y	Neutral	0.034
NOTCH3	Q9UM47-1.2	L2043A	Neutral	0.15
NOTCH3	Q9UM47-1.2	L2043C	Neutral	0.159
NOTCH3	Q9UM47-1.2	L2043D	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	L2043E	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	L2043F	Neutral	0.044
NOTCH3	Q9UM47-1.2	L2043G	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	L2043H	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	L2043I	Neutral	0.002
NOTCH3	Q9UM47-1.2	L2043K	Neutral	0.493
NOTCH3	Q9UM47-1.2	L2043M	Neutral	0.002
NOTCH3	Q9UM47-1.2	L2043N	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	L2043P	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	L2043Q	Neutral	0.492
NOTCH3	Q9UM47-1.2	L2043R	Neutral	0.48
NOTCH3	Q9UM47-1.2	L2043S	Neutral	0.452
NOTCH3	Q9UM47-1.2	L2043T	Neutral	0.163
NOTCH3	Q9UM47-1.2	L2043V	Neutral	0.01
NOTCH3	Q9UM47-1.2	L2043W	Neutral	0.461
NOTCH3	Q9UM47-1.2	L2043Y	Neutral	0.17
NOTCH3	Q9UM47-1.2	C2044A	Neutral	0.106
NOTCH3	Q9UM47-1.2	C2044D	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	C2044E	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	C2044F	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	C2044G	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	C2044H	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	C2044I	Neutral	0.334
NOTCH3	Q9UM47-1.2	C2044K	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	C2044L	Neutral	0.334
NOTCH3	Q9UM47-1.2	C2044M	Neutral	0.333
NOTCH3	Q9UM47-1.2	C2044N	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	C2044P	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	C2044Q	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	C2044R	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	C2044S	Neutral	0.357
NOTCH3	Q9UM47-1.2	C2044T	Neutral	0.361
NOTCH3	Q9UM47-1.2	C2044V	Neutral	0.35
NOTCH3	Q9UM47-1.2	C2044W	Pathogenic	0.664
NOTCH3	Q9UM47-1.2	C2044Y	Pathogenic	0.68
NOTCH3	Q9UM47-1.2	P2045A	Neutral	0.031
NOTCH3	Q9UM47-1.2	P2045C	Neutral	0.413
NOTCH3	Q9UM47-1.2	P2045D	Neutral	0.033
NOTCH3	Q9UM47-1.2	P2045E	Neutral	0.031
NOTCH3	Q9UM47-1.2	P2045F	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	P2045G	Neutral	0.118
NOTCH3	Q9UM47-1.2	P2045H	Neutral	0.124
NOTCH3	Q9UM47-1.2	P2045I	Neutral	0.387
NOTCH3	Q9UM47-1.2	P2045K	Neutral	0.028
NOTCH3	Q9UM47-1.2	P2045L	Neutral	0.386
NOTCH3	Q9UM47-1.2	P2045M	Neutral	0.121
NOTCH3	Q9UM47-1.2	P2045N	Neutral	0.134
NOTCH3	Q9UM47-1.2	P2045Q	Neutral	0.031
NOTCH3	Q9UM47-1.2	P2045R	Neutral	0.113
NOTCH3	Q9UM47-1.2	P2045S	Neutral	0.031
NOTCH3	Q9UM47-1.2	P2045T	Neutral	0.033
NOTCH3	Q9UM47-1.2	P2045V	Neutral	0.129
NOTCH3	Q9UM47-1.2	P2045W	Pathogenic	0.712
NOTCH3	Q9UM47-1.2	P2045Y	Neutral	0.369
NOTCH3	Q9UM47-1.2	P2046A	Neutral	0.429
NOTCH3	Q9UM47-1.2	P2046C	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	P2046D	Neutral	0.452
NOTCH3	Q9UM47-1.2	P2046E	Neutral	0.435
NOTCH3	Q9UM47-1.2	P2046F	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	P2046G	Pathogenic	0.761
NOTCH3	Q9UM47-1.2	P2046H	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	P2046I	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	P2046K	Neutral	0.411
NOTCH3	Q9UM47-1.2	P2046L	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	P2046M	Pathogenic	0.767
NOTCH3	Q9UM47-1.2	P2046N	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	P2046Q	Neutral	0.429
NOTCH3	Q9UM47-1.2	P2046R	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	P2046S	Neutral	0.436
NOTCH3	Q9UM47-1.2	P2046T	Neutral	0.448
NOTCH3	Q9UM47-1.2	P2046V	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	P2046W	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	P2046Y	Pathogenic	0.933
NOTCH3	Q9UM47-1.2	G2047A	Neutral	0.004
NOTCH3	Q9UM47-1.2	G2047C	Neutral	0.237
NOTCH3	Q9UM47-1.2	G2047D	Neutral	0.014
NOTCH3	Q9UM47-1.2	G2047E	Neutral	0.058
NOTCH3	Q9UM47-1.2	G2047F	Neutral	0.205
NOTCH3	Q9UM47-1.2	G2047H	Neutral	0.056
NOTCH3	Q9UM47-1.2	G2047I	Pathogenic	0.551
NOTCH3	Q9UM47-1.2	G2047K	Neutral	0.053
NOTCH3	Q9UM47-1.2	G2047L	Pathogenic	0.551
NOTCH3	Q9UM47-1.2	G2047M	Neutral	0.211
NOTCH3	Q9UM47-1.2	G2047N	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2047P	Neutral	0.063
NOTCH3	Q9UM47-1.2	G2047Q	Neutral	0.057
NOTCH3	Q9UM47-1.2	G2047R	Neutral	0.051
NOTCH3	Q9UM47-1.2	G2047S	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2047T	Neutral	0.062
NOTCH3	Q9UM47-1.2	G2047V	Neutral	0.224
NOTCH3	Q9UM47-1.2	G2047W	Neutral	0.049
NOTCH3	Q9UM47-1.2	G2047Y	Neutral	0.2
NOTCH3	Q9UM47-1.2	A2048C	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2048D	Neutral	0.101
NOTCH3	Q9UM47-1.2	A2048E	Neutral	0.023
NOTCH3	Q9UM47-1.2	A2048F	Neutral	0.087
NOTCH3	Q9UM47-1.2	A2048G	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2048H	Neutral	0.092
NOTCH3	Q9UM47-1.2	A2048I	Neutral	0.021
NOTCH3	Q9UM47-1.2	A2048K	Neutral	0.021
NOTCH3	Q9UM47-1.2	A2048L	Neutral	0.021
NOTCH3	Q9UM47-1.2	A2048M	Neutral	0.021
NOTCH3	Q9UM47-1.2	A2048N	Neutral	0.099
NOTCH3	Q9UM47-1.2	A2048P	Neutral	0.024
NOTCH3	Q9UM47-1.2	A2048Q	Neutral	0.022
NOTCH3	Q9UM47-1.2	A2048R	Neutral	0.02
NOTCH3	Q9UM47-1.2	A2048S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2048T	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2048V	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2048W	Neutral	0.281
NOTCH3	Q9UM47-1.2	A2048Y	Neutral	0.085
NOTCH3	Q9UM47-1.2	F2049A	Pathogenic	0.841
NOTCH3	Q9UM47-1.2	F2049C	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	F2049D	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	F2049E	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	F2049G	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	F2049H	Pathogenic	0.587
NOTCH3	Q9UM47-1.2	F2049I	Neutral	0.24
NOTCH3	Q9UM47-1.2	F2049K	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	F2049L	Neutral	0.24
NOTCH3	Q9UM47-1.2	F2049M	Neutral	0.24
NOTCH3	Q9UM47-1.2	F2049N	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	F2049P	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	F2049Q	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	F2049R	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	F2049S	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	F2049T	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	F2049V	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	F2049W	Neutral	0.061
NOTCH3	Q9UM47-1.2	F2049Y	Neutral	0.003
NOTCH3	Q9UM47-1.2	L2050A	Neutral	0.314
NOTCH3	Q9UM47-1.2	L2050C	Neutral	0.329
NOTCH3	Q9UM47-1.2	L2050D	Pathogenic	0.98
NOTCH3	Q9UM47-1.2	L2050E	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	L2050F	Neutral	0.106
NOTCH3	Q9UM47-1.2	L2050G	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	L2050H	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	L2050I	Neutral	0.006
NOTCH3	Q9UM47-1.2	L2050K	Pathogenic	0.716
NOTCH3	Q9UM47-1.2	L2050M	Neutral	0.006
NOTCH3	Q9UM47-1.2	L2050N	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	L2050P	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	L2050Q	Pathogenic	0.715
NOTCH3	Q9UM47-1.2	L2050R	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	L2050S	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	L2050T	Neutral	0.336
NOTCH3	Q9UM47-1.2	L2050V	Neutral	0.025
NOTCH3	Q9UM47-1.2	L2050W	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	L2050Y	Neutral	0.347
NOTCH3	Q9UM47-1.2	P2051A	Neutral	0.024
NOTCH3	Q9UM47-1.2	P2051C	Neutral	0.356
NOTCH3	Q9UM47-1.2	P2051D	Neutral	0.027
NOTCH3	Q9UM47-1.2	P2051E	Neutral	0.025
NOTCH3	Q9UM47-1.2	P2051F	Pathogenic	0.684
NOTCH3	Q9UM47-1.2	P2051G	Neutral	0.095
NOTCH3	Q9UM47-1.2	P2051H	Neutral	0.1
NOTCH3	Q9UM47-1.2	P2051I	Neutral	0.331
NOTCH3	Q9UM47-1.2	P2051K	Neutral	0.023
NOTCH3	Q9UM47-1.2	P2051L	Neutral	0.331
NOTCH3	Q9UM47-1.2	P2051M	Neutral	0.098
NOTCH3	Q9UM47-1.2	P2051N	Neutral	0.108
NOTCH3	Q9UM47-1.2	P2051Q	Neutral	0.024
NOTCH3	Q9UM47-1.2	P2051R	Neutral	0.091
NOTCH3	Q9UM47-1.2	P2051S	Neutral	0.025
NOTCH3	Q9UM47-1.2	P2051T	Neutral	0.026
NOTCH3	Q9UM47-1.2	P2051V	Neutral	0.104
NOTCH3	Q9UM47-1.2	P2051W	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	P2051Y	Neutral	0.315
NOTCH3	Q9UM47-1.2	G2052A	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2052C	Neutral	0.199
NOTCH3	Q9UM47-1.2	G2052D	Neutral	0.012
NOTCH3	Q9UM47-1.2	G2052E	Neutral	0.047
NOTCH3	Q9UM47-1.2	G2052F	Neutral	0.172
NOTCH3	Q9UM47-1.2	G2052H	Neutral	0.046
NOTCH3	Q9UM47-1.2	G2052I	Neutral	0.496
NOTCH3	Q9UM47-1.2	G2052K	Neutral	0.043
NOTCH3	Q9UM47-1.2	G2052L	Neutral	0.496
NOTCH3	Q9UM47-1.2	G2052M	Neutral	0.177
NOTCH3	Q9UM47-1.2	G2052N	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2052P	Neutral	0.051
NOTCH3	Q9UM47-1.2	G2052Q	Neutral	0.046
NOTCH3	Q9UM47-1.2	G2052R	Neutral	0.041
NOTCH3	Q9UM47-1.2	G2052S	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2052T	Neutral	0.05
NOTCH3	Q9UM47-1.2	G2052V	Neutral	0.188
NOTCH3	Q9UM47-1.2	G2052W	Neutral	0.039
NOTCH3	Q9UM47-1.2	G2052Y	Neutral	0.167
NOTCH3	Q9UM47-1.2	L2053A	Neutral	0.302
NOTCH3	Q9UM47-1.2	L2053C	Neutral	0.317
NOTCH3	Q9UM47-1.2	L2053D	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	L2053E	Pathogenic	0.914
NOTCH3	Q9UM47-1.2	L2053F	Neutral	0.101
NOTCH3	Q9UM47-1.2	L2053G	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	L2053H	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	L2053I	Neutral	0.006
NOTCH3	Q9UM47-1.2	L2053K	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	L2053M	Neutral	0.006
NOTCH3	Q9UM47-1.2	L2053N	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	L2053P	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	L2053Q	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	L2053R	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	L2053S	Pathogenic	0.669
NOTCH3	Q9UM47-1.2	L2053T	Neutral	0.324
NOTCH3	Q9UM47-1.2	L2053V	Neutral	0.023
NOTCH3	Q9UM47-1.2	L2053W	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	L2053Y	Neutral	0.334
NOTCH3	Q9UM47-1.2	K2054A	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	K2054C	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	K2054D	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	K2054E	Neutral	0.161
NOTCH3	Q9UM47-1.2	K2054F	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	K2054G	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	K2054H	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	K2054I	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	K2054L	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	K2054M	Pathogenic	0.81
NOTCH3	Q9UM47-1.2	K2054N	Neutral	0.454
NOTCH3	Q9UM47-1.2	K2054P	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	K2054Q	Neutral	0.164
NOTCH3	Q9UM47-1.2	K2054R	Neutral	0.042
NOTCH3	Q9UM47-1.2	K2054S	Neutral	0.433
NOTCH3	Q9UM47-1.2	K2054T	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	K2054V	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	K2054W	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	K2054Y	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	A2055C	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2055D	Neutral	0.023
NOTCH3	Q9UM47-1.2	A2055E	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2055F	Neutral	0.02
NOTCH3	Q9UM47-1.2	A2055G	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2055H	Neutral	0.021
NOTCH3	Q9UM47-1.2	A2055I	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2055K	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2055L	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2055M	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2055N	Neutral	0.023
NOTCH3	Q9UM47-1.2	A2055P	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2055Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2055R	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2055S	Neutral	0.0
NOTCH3	Q9UM47-1.2	A2055T	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2055V	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2055W	Neutral	0.076
NOTCH3	Q9UM47-1.2	A2055Y	Neutral	0.019
NOTCH3	Q9UM47-1.2	A2056C	Neutral	0.015
NOTCH3	Q9UM47-1.2	A2056D	Neutral	0.239
NOTCH3	Q9UM47-1.2	A2056E	Neutral	0.06
NOTCH3	Q9UM47-1.2	A2056F	Neutral	0.21
NOTCH3	Q9UM47-1.2	A2056G	Neutral	0.015
NOTCH3	Q9UM47-1.2	A2056H	Neutral	0.22
NOTCH3	Q9UM47-1.2	A2056I	Neutral	0.058
NOTCH3	Q9UM47-1.2	A2056K	Neutral	0.055
NOTCH3	Q9UM47-1.2	A2056L	Neutral	0.057
NOTCH3	Q9UM47-1.2	A2056M	Neutral	0.057
NOTCH3	Q9UM47-1.2	A2056N	Neutral	0.236
NOTCH3	Q9UM47-1.2	A2056P	Neutral	0.065
NOTCH3	Q9UM47-1.2	A2056Q	Neutral	0.059
NOTCH3	Q9UM47-1.2	A2056R	Neutral	0.053
NOTCH3	Q9UM47-1.2	A2056S	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2056T	Neutral	0.015
NOTCH3	Q9UM47-1.2	A2056V	Neutral	0.014
NOTCH3	Q9UM47-1.2	A2056W	Pathogenic	0.522
NOTCH3	Q9UM47-1.2	A2056Y	Neutral	0.205
NOTCH3	Q9UM47-1.2	Q2057A	Neutral	0.021
NOTCH3	Q9UM47-1.2	Q2057C	Neutral	0.329
NOTCH3	Q9UM47-1.2	Q2057D	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q2057E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q2057F	Neutral	0.337
NOTCH3	Q9UM47-1.2	Q2057G	Neutral	0.085
NOTCH3	Q9UM47-1.2	Q2057H	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q2057I	Neutral	0.346
NOTCH3	Q9UM47-1.2	Q2057K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q2057L	Neutral	0.104
NOTCH3	Q9UM47-1.2	Q2057M	Neutral	0.006
NOTCH3	Q9UM47-1.2	Q2057N	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q2057P	Neutral	0.023
NOTCH3	Q9UM47-1.2	Q2057R	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q2057S	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q2057T	Neutral	0.024
NOTCH3	Q9UM47-1.2	Q2057V	Neutral	0.104
NOTCH3	Q9UM47-1.2	Q2057W	Neutral	0.091
NOTCH3	Q9UM47-1.2	Q2057Y	Neutral	0.023
NOTCH3	Q9UM47-1.2	S2058A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2058C	Neutral	0.027
NOTCH3	Q9UM47-1.2	S2058D	Neutral	0.006
NOTCH3	Q9UM47-1.2	S2058E	Neutral	0.006
NOTCH3	Q9UM47-1.2	S2058F	Neutral	0.095
NOTCH3	Q9UM47-1.2	S2058G	Neutral	0.006
NOTCH3	Q9UM47-1.2	S2058H	Neutral	0.024
NOTCH3	Q9UM47-1.2	S2058I	Neutral	0.099
NOTCH3	Q9UM47-1.2	S2058K	Neutral	0.005
NOTCH3	Q9UM47-1.2	S2058L	Neutral	0.099
NOTCH3	Q9UM47-1.2	S2058M	Neutral	0.023
NOTCH3	Q9UM47-1.2	S2058N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2058P	Neutral	0.027
NOTCH3	Q9UM47-1.2	S2058Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	S2058R	Neutral	0.021
NOTCH3	Q9UM47-1.2	S2058T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2058V	Neutral	0.105
NOTCH3	Q9UM47-1.2	S2058W	Neutral	0.302
NOTCH3	Q9UM47-1.2	S2058Y	Neutral	0.093
NOTCH3	Q9UM47-1.2	G2059A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2059C	Neutral	0.136
NOTCH3	Q9UM47-1.2	G2059D	Neutral	0.007
NOTCH3	Q9UM47-1.2	G2059E	Neutral	0.031
NOTCH3	Q9UM47-1.2	G2059F	Neutral	0.116
NOTCH3	Q9UM47-1.2	G2059H	Neutral	0.029
NOTCH3	Q9UM47-1.2	G2059I	Neutral	0.384
NOTCH3	Q9UM47-1.2	G2059K	Neutral	0.028
NOTCH3	Q9UM47-1.2	G2059L	Neutral	0.384
NOTCH3	Q9UM47-1.2	G2059M	Neutral	0.12
NOTCH3	Q9UM47-1.2	G2059N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2059P	Neutral	0.033
NOTCH3	Q9UM47-1.2	G2059Q	Neutral	0.03
NOTCH3	Q9UM47-1.2	G2059R	Neutral	0.027
NOTCH3	Q9UM47-1.2	G2059S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2059T	Neutral	0.032
NOTCH3	Q9UM47-1.2	G2059V	Neutral	0.128
NOTCH3	Q9UM47-1.2	G2059W	Neutral	0.025
NOTCH3	Q9UM47-1.2	G2059Y	Neutral	0.113
NOTCH3	Q9UM47-1.2	S2060A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2060C	Neutral	0.021
NOTCH3	Q9UM47-1.2	S2060D	Neutral	0.005
NOTCH3	Q9UM47-1.2	S2060E	Neutral	0.004
NOTCH3	Q9UM47-1.2	S2060F	Neutral	0.076
NOTCH3	Q9UM47-1.2	S2060G	Neutral	0.004
NOTCH3	Q9UM47-1.2	S2060H	Neutral	0.019
NOTCH3	Q9UM47-1.2	S2060I	Neutral	0.079
NOTCH3	Q9UM47-1.2	S2060K	Neutral	0.004
NOTCH3	Q9UM47-1.2	S2060L	Neutral	0.079
NOTCH3	Q9UM47-1.2	S2060M	Neutral	0.018
NOTCH3	Q9UM47-1.2	S2060N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2060P	Neutral	0.021
NOTCH3	Q9UM47-1.2	S2060Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	S2060R	Neutral	0.017
NOTCH3	Q9UM47-1.2	S2060T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2060V	Neutral	0.084
NOTCH3	Q9UM47-1.2	S2060W	Neutral	0.252
NOTCH3	Q9UM47-1.2	S2060Y	Neutral	0.074
NOTCH3	Q9UM47-1.2	K2061A	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	K2061C	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	K2061D	Pathogenic	0.863
NOTCH3	Q9UM47-1.2	K2061E	Neutral	0.246
NOTCH3	Q9UM47-1.2	K2061F	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	K2061G	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	K2061H	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	K2061I	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	K2061L	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	K2061M	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	K2061N	Pathogenic	0.586
NOTCH3	Q9UM47-1.2	K2061P	Pathogenic	0.864
NOTCH3	Q9UM47-1.2	K2061Q	Neutral	0.251
NOTCH3	Q9UM47-1.2	K2061R	Neutral	0.07
NOTCH3	Q9UM47-1.2	K2061S	Pathogenic	0.566
NOTCH3	Q9UM47-1.2	K2061T	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	K2061V	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	K2061W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	K2061Y	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	K2062A	Pathogenic	0.838
NOTCH3	Q9UM47-1.2	K2062C	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	K2062D	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	K2062E	Neutral	0.225
NOTCH3	Q9UM47-1.2	K2062F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	K2062G	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	K2062H	Pathogenic	0.863
NOTCH3	Q9UM47-1.2	K2062I	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	K2062L	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	K2062M	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	K2062N	Pathogenic	0.558
NOTCH3	Q9UM47-1.2	K2062P	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	K2062Q	Neutral	0.229
NOTCH3	Q9UM47-1.2	K2062R	Neutral	0.063
NOTCH3	Q9UM47-1.2	K2062S	Pathogenic	0.537
NOTCH3	Q9UM47-1.2	K2062T	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	K2062V	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	K2062W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	K2062Y	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	S2063A	Neutral	0.003
NOTCH3	Q9UM47-1.2	S2063C	Neutral	0.049
NOTCH3	Q9UM47-1.2	S2063D	Neutral	0.011
NOTCH3	Q9UM47-1.2	S2063E	Neutral	0.01
NOTCH3	Q9UM47-1.2	S2063F	Neutral	0.163
NOTCH3	Q9UM47-1.2	S2063G	Neutral	0.011
NOTCH3	Q9UM47-1.2	S2063H	Neutral	0.043
NOTCH3	Q9UM47-1.2	S2063I	Neutral	0.169
NOTCH3	Q9UM47-1.2	S2063K	Neutral	0.009
NOTCH3	Q9UM47-1.2	S2063L	Neutral	0.169
NOTCH3	Q9UM47-1.2	S2063M	Neutral	0.042
NOTCH3	Q9UM47-1.2	S2063N	Neutral	0.002
NOTCH3	Q9UM47-1.2	S2063P	Neutral	0.048
NOTCH3	Q9UM47-1.2	S2063Q	Neutral	0.01
NOTCH3	Q9UM47-1.2	S2063R	Neutral	0.039
NOTCH3	Q9UM47-1.2	S2063T	Neutral	0.002
NOTCH3	Q9UM47-1.2	S2063V	Neutral	0.179
NOTCH3	Q9UM47-1.2	S2063W	Neutral	0.444
NOTCH3	Q9UM47-1.2	S2063Y	Neutral	0.159
NOTCH3	Q9UM47-1.2	R2064A	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	R2064C	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	R2064D	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	R2064E	Neutral	0.428
NOTCH3	Q9UM47-1.2	R2064F	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	R2064G	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	R2064H	Neutral	0.438
NOTCH3	Q9UM47-1.2	R2064I	Pathogenic	0.987
NOTCH3	Q9UM47-1.2	R2064K	Neutral	0.038
NOTCH3	Q9UM47-1.2	R2064L	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	R2064M	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	R2064N	Neutral	0.416
NOTCH3	Q9UM47-1.2	R2064P	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	R2064Q	Neutral	0.144
NOTCH3	Q9UM47-1.2	R2064S	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	R2064T	Pathogenic	0.763
NOTCH3	Q9UM47-1.2	R2064V	Pathogenic	0.986
NOTCH3	Q9UM47-1.2	R2064W	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	R2064Y	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	R2065A	Neutral	0.332
NOTCH3	Q9UM47-1.2	R2065C	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	R2065D	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	R2065E	Neutral	0.113
NOTCH3	Q9UM47-1.2	R2065F	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	R2065G	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	R2065H	Neutral	0.117
NOTCH3	Q9UM47-1.2	R2065I	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	R2065K	Neutral	0.007
NOTCH3	Q9UM47-1.2	R2065L	Pathogenic	0.74
NOTCH3	Q9UM47-1.2	R2065M	Neutral	0.384
NOTCH3	Q9UM47-1.2	R2065N	Neutral	0.108
NOTCH3	Q9UM47-1.2	R2065P	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	R2065Q	Neutral	0.028
NOTCH3	Q9UM47-1.2	R2065S	Neutral	0.336
NOTCH3	Q9UM47-1.2	R2065T	Neutral	0.354
NOTCH3	Q9UM47-1.2	R2065V	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	R2065W	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	R2065Y	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	P2066A	Neutral	0.431
NOTCH3	Q9UM47-1.2	P2066C	Pathogenic	0.944
NOTCH3	Q9UM47-1.2	P2066D	Neutral	0.454
NOTCH3	Q9UM47-1.2	P2066E	Neutral	0.436
NOTCH3	Q9UM47-1.2	P2066F	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	P2066G	Pathogenic	0.762
NOTCH3	Q9UM47-1.2	P2066H	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	P2066I	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	P2066K	Neutral	0.413
NOTCH3	Q9UM47-1.2	P2066L	Pathogenic	0.938
NOTCH3	Q9UM47-1.2	P2066M	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	P2066N	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	P2066Q	Neutral	0.431
NOTCH3	Q9UM47-1.2	P2066R	Pathogenic	0.753
NOTCH3	Q9UM47-1.2	P2066S	Neutral	0.437
NOTCH3	Q9UM47-1.2	P2066T	Neutral	0.45
NOTCH3	Q9UM47-1.2	P2066V	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	P2066W	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	P2066Y	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	P2067A	Neutral	0.009
NOTCH3	Q9UM47-1.2	P2067C	Neutral	0.172
NOTCH3	Q9UM47-1.2	P2067D	Neutral	0.01
NOTCH3	Q9UM47-1.2	P2067E	Neutral	0.009
NOTCH3	Q9UM47-1.2	P2067F	Neutral	0.449
NOTCH3	Q9UM47-1.2	P2067G	Neutral	0.038
NOTCH3	Q9UM47-1.2	P2067H	Neutral	0.04
NOTCH3	Q9UM47-1.2	P2067I	Neutral	0.157
NOTCH3	Q9UM47-1.2	P2067K	Neutral	0.009
NOTCH3	Q9UM47-1.2	P2067L	Neutral	0.157
NOTCH3	Q9UM47-1.2	P2067M	Neutral	0.039
NOTCH3	Q9UM47-1.2	P2067N	Neutral	0.044
NOTCH3	Q9UM47-1.2	P2067Q	Neutral	0.009
NOTCH3	Q9UM47-1.2	P2067R	Neutral	0.036
NOTCH3	Q9UM47-1.2	P2067S	Neutral	0.01
NOTCH3	Q9UM47-1.2	P2067T	Neutral	0.01
NOTCH3	Q9UM47-1.2	P2067V	Neutral	0.042
NOTCH3	Q9UM47-1.2	P2067W	Neutral	0.424
NOTCH3	Q9UM47-1.2	P2067Y	Neutral	0.148
NOTCH3	Q9UM47-1.2	G2068A	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2068C	Neutral	0.227
NOTCH3	Q9UM47-1.2	G2068D	Neutral	0.014
NOTCH3	Q9UM47-1.2	G2068E	Neutral	0.056
NOTCH3	Q9UM47-1.2	G2068F	Neutral	0.197
NOTCH3	Q9UM47-1.2	G2068H	Neutral	0.054
NOTCH3	Q9UM47-1.2	G2068I	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	G2068K	Neutral	0.051
NOTCH3	Q9UM47-1.2	G2068L	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	G2068M	Neutral	0.203
NOTCH3	Q9UM47-1.2	G2068N	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2068P	Neutral	0.06
NOTCH3	Q9UM47-1.2	G2068Q	Neutral	0.055
NOTCH3	Q9UM47-1.2	G2068R	Neutral	0.048
NOTCH3	Q9UM47-1.2	G2068S	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2068T	Neutral	0.059
NOTCH3	Q9UM47-1.2	G2068V	Neutral	0.215
NOTCH3	Q9UM47-1.2	G2068W	Neutral	0.046
NOTCH3	Q9UM47-1.2	G2068Y	Neutral	0.192
NOTCH3	Q9UM47-1.2	K2069A	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	K2069C	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	K2069D	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	K2069E	Neutral	0.17
NOTCH3	Q9UM47-1.2	K2069F	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	K2069G	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	K2069H	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	K2069I	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	K2069L	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	K2069M	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	K2069N	Neutral	0.469
NOTCH3	Q9UM47-1.2	K2069P	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	K2069Q	Neutral	0.173
NOTCH3	Q9UM47-1.2	K2069R	Neutral	0.045
NOTCH3	Q9UM47-1.2	K2069S	Neutral	0.449
NOTCH3	Q9UM47-1.2	K2069T	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	K2069V	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	K2069W	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	K2069Y	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	A2070C	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2070D	Neutral	0.077
NOTCH3	Q9UM47-1.2	A2070E	Neutral	0.017
NOTCH3	Q9UM47-1.2	A2070F	Neutral	0.066
NOTCH3	Q9UM47-1.2	A2070G	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2070H	Neutral	0.069
NOTCH3	Q9UM47-1.2	A2070I	Neutral	0.016
NOTCH3	Q9UM47-1.2	A2070K	Neutral	0.015
NOTCH3	Q9UM47-1.2	A2070L	Neutral	0.016
NOTCH3	Q9UM47-1.2	A2070M	Neutral	0.016
NOTCH3	Q9UM47-1.2	A2070N	Neutral	0.076
NOTCH3	Q9UM47-1.2	A2070P	Neutral	0.018
NOTCH3	Q9UM47-1.2	A2070Q	Neutral	0.016
NOTCH3	Q9UM47-1.2	A2070R	Neutral	0.015
NOTCH3	Q9UM47-1.2	A2070S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2070T	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2070V	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2070W	Neutral	0.225
NOTCH3	Q9UM47-1.2	A2070Y	Neutral	0.064
NOTCH3	Q9UM47-1.2	G2071A	Neutral	0.047
NOTCH3	Q9UM47-1.2	G2071C	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	G2071D	Neutral	0.171
NOTCH3	Q9UM47-1.2	G2071E	Neutral	0.466
NOTCH3	Q9UM47-1.2	G2071F	Pathogenic	0.784
NOTCH3	Q9UM47-1.2	G2071H	Neutral	0.456
NOTCH3	Q9UM47-1.2	G2071I	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	G2071K	Neutral	0.442
NOTCH3	Q9UM47-1.2	G2071L	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	G2071M	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	G2071N	Neutral	0.042
NOTCH3	Q9UM47-1.2	G2071P	Neutral	0.485
NOTCH3	Q9UM47-1.2	G2071Q	Neutral	0.46
NOTCH3	Q9UM47-1.2	G2071R	Neutral	0.43
NOTCH3	Q9UM47-1.2	G2071S	Neutral	0.046
NOTCH3	Q9UM47-1.2	G2071T	Neutral	0.481
NOTCH3	Q9UM47-1.2	G2071V	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	G2071W	Neutral	0.418
NOTCH3	Q9UM47-1.2	G2071Y	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	L2072A	Neutral	0.16
NOTCH3	Q9UM47-1.2	L2072C	Neutral	0.169
NOTCH3	Q9UM47-1.2	L2072D	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	L2072E	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	L2072F	Neutral	0.047
NOTCH3	Q9UM47-1.2	L2072G	Pathogenic	0.943
NOTCH3	Q9UM47-1.2	L2072H	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	L2072I	Neutral	0.002
NOTCH3	Q9UM47-1.2	L2072K	Pathogenic	0.511
NOTCH3	Q9UM47-1.2	L2072M	Neutral	0.002
NOTCH3	Q9UM47-1.2	L2072N	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	L2072P	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	L2072Q	Pathogenic	0.51
NOTCH3	Q9UM47-1.2	L2072R	Neutral	0.498
NOTCH3	Q9UM47-1.2	L2072S	Neutral	0.47
NOTCH3	Q9UM47-1.2	L2072T	Neutral	0.174
NOTCH3	Q9UM47-1.2	L2072V	Neutral	0.01
NOTCH3	Q9UM47-1.2	L2072W	Neutral	0.479
NOTCH3	Q9UM47-1.2	L2072Y	Neutral	0.181
NOTCH3	Q9UM47-1.2	G2073A	Neutral	0.008
NOTCH3	Q9UM47-1.2	G2073C	Neutral	0.407
NOTCH3	Q9UM47-1.2	G2073D	Neutral	0.031
NOTCH3	Q9UM47-1.2	G2073E	Neutral	0.121
NOTCH3	Q9UM47-1.2	G2073F	Neutral	0.363
NOTCH3	Q9UM47-1.2	G2073H	Neutral	0.117
NOTCH3	Q9UM47-1.2	G2073I	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	G2073K	Neutral	0.111
NOTCH3	Q9UM47-1.2	G2073L	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	G2073M	Neutral	0.372
NOTCH3	Q9UM47-1.2	G2073N	Neutral	0.007
NOTCH3	Q9UM47-1.2	G2073P	Neutral	0.129
NOTCH3	Q9UM47-1.2	G2073Q	Neutral	0.118
NOTCH3	Q9UM47-1.2	G2073R	Neutral	0.106
NOTCH3	Q9UM47-1.2	G2073S	Neutral	0.008
NOTCH3	Q9UM47-1.2	G2073T	Neutral	0.127
NOTCH3	Q9UM47-1.2	G2073V	Neutral	0.389
NOTCH3	Q9UM47-1.2	G2073W	Neutral	0.102
NOTCH3	Q9UM47-1.2	G2073Y	Neutral	0.357
NOTCH3	Q9UM47-1.2	P2074A	Neutral	0.015
NOTCH3	Q9UM47-1.2	P2074C	Neutral	0.255
NOTCH3	Q9UM47-1.2	P2074D	Neutral	0.017
NOTCH3	Q9UM47-1.2	P2074E	Neutral	0.015
NOTCH3	Q9UM47-1.2	P2074F	Pathogenic	0.572
NOTCH3	Q9UM47-1.2	P2074G	Neutral	0.061
NOTCH3	Q9UM47-1.2	P2074H	Neutral	0.064
NOTCH3	Q9UM47-1.2	P2074I	Neutral	0.234
NOTCH3	Q9UM47-1.2	P2074K	Neutral	0.014
NOTCH3	Q9UM47-1.2	P2074L	Neutral	0.234
NOTCH3	Q9UM47-1.2	P2074M	Neutral	0.063
NOTCH3	Q9UM47-1.2	P2074N	Neutral	0.07
NOTCH3	Q9UM47-1.2	P2074Q	Neutral	0.015
NOTCH3	Q9UM47-1.2	P2074R	Neutral	0.058
NOTCH3	Q9UM47-1.2	P2074S	Neutral	0.015
NOTCH3	Q9UM47-1.2	P2074T	Neutral	0.016
NOTCH3	Q9UM47-1.2	P2074V	Neutral	0.067
NOTCH3	Q9UM47-1.2	P2074W	Pathogenic	0.546
NOTCH3	Q9UM47-1.2	P2074Y	Neutral	0.222
NOTCH3	Q9UM47-1.2	Q2075A	Neutral	0.037
NOTCH3	Q9UM47-1.2	Q2075C	Neutral	0.461
NOTCH3	Q9UM47-1.2	Q2075D	Neutral	0.009
NOTCH3	Q9UM47-1.2	Q2075E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q2075F	Neutral	0.469
NOTCH3	Q9UM47-1.2	Q2075G	Neutral	0.138
NOTCH3	Q9UM47-1.2	Q2075H	Neutral	0.01
NOTCH3	Q9UM47-1.2	Q2075I	Neutral	0.48
NOTCH3	Q9UM47-1.2	Q2075K	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q2075L	Neutral	0.168
NOTCH3	Q9UM47-1.2	Q2075M	Neutral	0.01
NOTCH3	Q9UM47-1.2	Q2075N	Neutral	0.009
NOTCH3	Q9UM47-1.2	Q2075P	Neutral	0.04
NOTCH3	Q9UM47-1.2	Q2075R	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q2075S	Neutral	0.008
NOTCH3	Q9UM47-1.2	Q2075T	Neutral	0.04
NOTCH3	Q9UM47-1.2	Q2075V	Neutral	0.168
NOTCH3	Q9UM47-1.2	Q2075W	Neutral	0.149
NOTCH3	Q9UM47-1.2	Q2075Y	Neutral	0.04
NOTCH3	Q9UM47-1.2	G2076A	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2076C	Neutral	0.234
NOTCH3	Q9UM47-1.2	G2076D	Neutral	0.014
NOTCH3	Q9UM47-1.2	G2076E	Neutral	0.058
NOTCH3	Q9UM47-1.2	G2076F	Neutral	0.203
NOTCH3	Q9UM47-1.2	G2076H	Neutral	0.056
NOTCH3	Q9UM47-1.2	G2076I	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	G2076K	Neutral	0.053
NOTCH3	Q9UM47-1.2	G2076L	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	G2076M	Neutral	0.21
NOTCH3	Q9UM47-1.2	G2076N	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2076P	Neutral	0.062
NOTCH3	Q9UM47-1.2	G2076Q	Neutral	0.057
NOTCH3	Q9UM47-1.2	G2076R	Neutral	0.05
NOTCH3	Q9UM47-1.2	G2076S	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2076T	Neutral	0.061
NOTCH3	Q9UM47-1.2	G2076V	Neutral	0.222
NOTCH3	Q9UM47-1.2	G2076W	Neutral	0.048
NOTCH3	Q9UM47-1.2	G2076Y	Neutral	0.199
NOTCH3	Q9UM47-1.2	P2077A	Neutral	0.001
NOTCH3	Q9UM47-1.2	P2077C	Neutral	0.015
NOTCH3	Q9UM47-1.2	P2077D	Neutral	0.001
NOTCH3	Q9UM47-1.2	P2077E	Neutral	0.001
NOTCH3	Q9UM47-1.2	P2077F	Neutral	0.056
NOTCH3	Q9UM47-1.2	P2077G	Neutral	0.003
NOTCH3	Q9UM47-1.2	P2077H	Neutral	0.003
NOTCH3	Q9UM47-1.2	P2077I	Neutral	0.013
NOTCH3	Q9UM47-1.2	P2077K	Neutral	0.001
NOTCH3	Q9UM47-1.2	P2077L	Neutral	0.013
NOTCH3	Q9UM47-1.2	P2077M	Neutral	0.003
NOTCH3	Q9UM47-1.2	P2077N	Neutral	0.003
NOTCH3	Q9UM47-1.2	P2077Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	P2077R	Neutral	0.003
NOTCH3	Q9UM47-1.2	P2077S	Neutral	0.001
NOTCH3	Q9UM47-1.2	P2077T	Neutral	0.001
NOTCH3	Q9UM47-1.2	P2077V	Neutral	0.003
NOTCH3	Q9UM47-1.2	P2077W	Neutral	0.051
NOTCH3	Q9UM47-1.2	P2077Y	Neutral	0.013
NOTCH3	Q9UM47-1.2	R2078A	Neutral	0.052
NOTCH3	Q9UM47-1.2	R2078C	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	R2078D	Neutral	0.215
NOTCH3	Q9UM47-1.2	R2078E	Neutral	0.014
NOTCH3	Q9UM47-1.2	R2078F	Pathogenic	0.602
NOTCH3	Q9UM47-1.2	R2078G	Neutral	0.189
NOTCH3	Q9UM47-1.2	R2078H	Neutral	0.015
NOTCH3	Q9UM47-1.2	R2078I	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	R2078K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R2078L	Neutral	0.241
NOTCH3	Q9UM47-1.2	R2078M	Neutral	0.065
NOTCH3	Q9UM47-1.2	R2078N	Neutral	0.013
NOTCH3	Q9UM47-1.2	R2078P	Neutral	0.217
NOTCH3	Q9UM47-1.2	R2078Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R2078S	Neutral	0.053
NOTCH3	Q9UM47-1.2	R2078T	Neutral	0.058
NOTCH3	Q9UM47-1.2	R2078V	Pathogenic	0.572
NOTCH3	Q9UM47-1.2	R2078W	Pathogenic	0.601
NOTCH3	Q9UM47-1.2	R2078Y	Neutral	0.252
NOTCH3	Q9UM47-1.2	G2079A	Neutral	0.008
NOTCH3	Q9UM47-1.2	G2079C	Neutral	0.43
NOTCH3	Q9UM47-1.2	G2079D	Neutral	0.034
NOTCH3	Q9UM47-1.2	G2079E	Neutral	0.131
NOTCH3	Q9UM47-1.2	G2079F	Neutral	0.386
NOTCH3	Q9UM47-1.2	G2079H	Neutral	0.127
NOTCH3	Q9UM47-1.2	G2079I	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	G2079K	Neutral	0.121
NOTCH3	Q9UM47-1.2	G2079L	Pathogenic	0.749
NOTCH3	Q9UM47-1.2	G2079M	Neutral	0.395
NOTCH3	Q9UM47-1.2	G2079N	Neutral	0.008
NOTCH3	Q9UM47-1.2	G2079P	Neutral	0.14
NOTCH3	Q9UM47-1.2	G2079Q	Neutral	0.129
NOTCH3	Q9UM47-1.2	G2079R	Neutral	0.115
NOTCH3	Q9UM47-1.2	G2079S	Neutral	0.008
NOTCH3	Q9UM47-1.2	G2079T	Neutral	0.138
NOTCH3	Q9UM47-1.2	G2079V	Neutral	0.412
NOTCH3	Q9UM47-1.2	G2079W	Neutral	0.111
NOTCH3	Q9UM47-1.2	G2079Y	Neutral	0.379
NOTCH3	Q9UM47-1.2	R2080A	Neutral	0.285
NOTCH3	Q9UM47-1.2	R2080C	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	R2080D	Pathogenic	0.664
NOTCH3	Q9UM47-1.2	R2080E	Neutral	0.093
NOTCH3	Q9UM47-1.2	R2080F	Pathogenic	0.916
NOTCH3	Q9UM47-1.2	R2080G	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	R2080H	Neutral	0.096
NOTCH3	Q9UM47-1.2	R2080I	Pathogenic	0.912
NOTCH3	Q9UM47-1.2	R2080K	Neutral	0.005
NOTCH3	Q9UM47-1.2	R2080L	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	R2080M	Neutral	0.333
NOTCH3	Q9UM47-1.2	R2080N	Neutral	0.089
NOTCH3	Q9UM47-1.2	R2080P	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	R2080Q	Neutral	0.022
NOTCH3	Q9UM47-1.2	R2080S	Neutral	0.289
NOTCH3	Q9UM47-1.2	R2080T	Neutral	0.306
NOTCH3	Q9UM47-1.2	R2080V	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	R2080W	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	R2080Y	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	G2081A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2081C	Neutral	0.159
NOTCH3	Q9UM47-1.2	G2081D	Neutral	0.009
NOTCH3	Q9UM47-1.2	G2081E	Neutral	0.036
NOTCH3	Q9UM47-1.2	G2081F	Neutral	0.136
NOTCH3	Q9UM47-1.2	G2081H	Neutral	0.035
NOTCH3	Q9UM47-1.2	G2081I	Neutral	0.428
NOTCH3	Q9UM47-1.2	G2081K	Neutral	0.033
NOTCH3	Q9UM47-1.2	G2081L	Neutral	0.428
NOTCH3	Q9UM47-1.2	G2081M	Neutral	0.14
NOTCH3	Q9UM47-1.2	G2081N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2081P	Neutral	0.039
NOTCH3	Q9UM47-1.2	G2081Q	Neutral	0.036
NOTCH3	Q9UM47-1.2	G2081R	Neutral	0.032
NOTCH3	Q9UM47-1.2	G2081S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2081T	Neutral	0.039
NOTCH3	Q9UM47-1.2	G2081V	Neutral	0.15
NOTCH3	Q9UM47-1.2	G2081W	Neutral	0.03
NOTCH3	Q9UM47-1.2	G2081Y	Neutral	0.133
NOTCH3	Q9UM47-1.2	K2082A	Neutral	0.436
NOTCH3	Q9UM47-1.2	K2082C	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	K2082D	Neutral	0.456
NOTCH3	Q9UM47-1.2	K2082E	Neutral	0.042
NOTCH3	Q9UM47-1.2	K2082F	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	K2082G	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	K2082H	Neutral	0.484
NOTCH3	Q9UM47-1.2	K2082I	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	K2082L	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	K2082M	Neutral	0.492
NOTCH3	Q9UM47-1.2	K2082N	Neutral	0.158
NOTCH3	Q9UM47-1.2	K2082P	Neutral	0.459
NOTCH3	Q9UM47-1.2	K2082Q	Neutral	0.043
NOTCH3	Q9UM47-1.2	K2082R	Neutral	0.01
NOTCH3	Q9UM47-1.2	K2082S	Neutral	0.148
NOTCH3	Q9UM47-1.2	K2082T	Neutral	0.46
NOTCH3	Q9UM47-1.2	K2082V	Pathogenic	0.804
NOTCH3	Q9UM47-1.2	K2082W	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	K2082Y	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	K2083A	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	K2083C	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	K2083D	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	K2083E	Neutral	0.24
NOTCH3	Q9UM47-1.2	K2083F	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	K2083G	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	K2083H	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	K2083I	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	K2083L	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	K2083M	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	K2083N	Pathogenic	0.578
NOTCH3	Q9UM47-1.2	K2083P	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	K2083Q	Neutral	0.245
NOTCH3	Q9UM47-1.2	K2083R	Neutral	0.068
NOTCH3	Q9UM47-1.2	K2083S	Pathogenic	0.558
NOTCH3	Q9UM47-1.2	K2083T	Pathogenic	0.861
NOTCH3	Q9UM47-1.2	K2083V	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	K2083W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	K2083Y	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	L2084A	Neutral	0.037
NOTCH3	Q9UM47-1.2	L2084C	Neutral	0.039
NOTCH3	Q9UM47-1.2	L2084D	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	L2084E	Neutral	0.483
NOTCH3	Q9UM47-1.2	L2084F	Neutral	0.01
NOTCH3	Q9UM47-1.2	L2084G	Pathogenic	0.77
NOTCH3	Q9UM47-1.2	L2084H	Neutral	0.49
NOTCH3	Q9UM47-1.2	L2084I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2084K	Neutral	0.173
NOTCH3	Q9UM47-1.2	L2084M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2084N	Neutral	0.47
NOTCH3	Q9UM47-1.2	L2084P	Neutral	0.462
NOTCH3	Q9UM47-1.2	L2084Q	Neutral	0.173
NOTCH3	Q9UM47-1.2	L2084R	Neutral	0.166
NOTCH3	Q9UM47-1.2	L2084S	Neutral	0.151
NOTCH3	Q9UM47-1.2	L2084T	Neutral	0.04
NOTCH3	Q9UM47-1.2	L2084V	Neutral	0.002
NOTCH3	Q9UM47-1.2	L2084W	Neutral	0.156
NOTCH3	Q9UM47-1.2	L2084Y	Neutral	0.042
NOTCH3	Q9UM47-1.2	T2085A	Neutral	0.009
NOTCH3	Q9UM47-1.2	T2085C	Neutral	0.044
NOTCH3	Q9UM47-1.2	T2085D	Neutral	0.045
NOTCH3	Q9UM47-1.2	T2085E	Neutral	0.042
NOTCH3	Q9UM47-1.2	T2085F	Neutral	0.155
NOTCH3	Q9UM47-1.2	T2085G	Neutral	0.152
NOTCH3	Q9UM47-1.2	T2085H	Neutral	0.162
NOTCH3	Q9UM47-1.2	T2085I	Neutral	0.04
NOTCH3	Q9UM47-1.2	T2085K	Neutral	0.039
NOTCH3	Q9UM47-1.2	T2085L	Neutral	0.04
NOTCH3	Q9UM47-1.2	T2085M	Neutral	0.04
NOTCH3	Q9UM47-1.2	T2085N	Neutral	0.01
NOTCH3	Q9UM47-1.2	T2085P	Neutral	0.044
NOTCH3	Q9UM47-1.2	T2085Q	Neutral	0.041
NOTCH3	Q9UM47-1.2	T2085R	Neutral	0.037
NOTCH3	Q9UM47-1.2	T2085S	Neutral	0.002
NOTCH3	Q9UM47-1.2	T2085V	Neutral	0.01
NOTCH3	Q9UM47-1.2	T2085W	Neutral	0.142
NOTCH3	Q9UM47-1.2	T2085Y	Neutral	0.151
NOTCH3	Q9UM47-1.2	L2086A	Neutral	0.081
NOTCH3	Q9UM47-1.2	L2086C	Neutral	0.086
NOTCH3	Q9UM47-1.2	L2086D	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	L2086E	Pathogenic	0.683
NOTCH3	Q9UM47-1.2	L2086F	Neutral	0.022
NOTCH3	Q9UM47-1.2	L2086G	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	L2086H	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	L2086I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2086K	Neutral	0.326
NOTCH3	Q9UM47-1.2	L2086M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2086N	Pathogenic	0.672
NOTCH3	Q9UM47-1.2	L2086P	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	L2086Q	Neutral	0.325
NOTCH3	Q9UM47-1.2	L2086R	Neutral	0.315
NOTCH3	Q9UM47-1.2	L2086S	Neutral	0.291
NOTCH3	Q9UM47-1.2	L2086T	Neutral	0.089
NOTCH3	Q9UM47-1.2	L2086V	Neutral	0.005
NOTCH3	Q9UM47-1.2	L2086W	Neutral	0.299
NOTCH3	Q9UM47-1.2	L2086Y	Neutral	0.093
NOTCH3	Q9UM47-1.2	A2087C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2087D	Neutral	0.056
NOTCH3	Q9UM47-1.2	A2087E	Neutral	0.012
NOTCH3	Q9UM47-1.2	A2087F	Neutral	0.048
NOTCH3	Q9UM47-1.2	A2087G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2087H	Neutral	0.051
NOTCH3	Q9UM47-1.2	A2087I	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2087K	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2087L	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2087M	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2087N	Neutral	0.055
NOTCH3	Q9UM47-1.2	A2087P	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2087Q	Neutral	0.012
NOTCH3	Q9UM47-1.2	A2087R	Neutral	0.01
NOTCH3	Q9UM47-1.2	A2087S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2087T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2087V	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2087W	Neutral	0.171
NOTCH3	Q9UM47-1.2	A2087Y	Neutral	0.047
NOTCH3	Q9UM47-1.2	C2088A	Neutral	0.002
NOTCH3	Q9UM47-1.2	C2088D	Neutral	0.151
NOTCH3	Q9UM47-1.2	C2088E	Neutral	0.429
NOTCH3	Q9UM47-1.2	C2088F	Neutral	0.032
NOTCH3	Q9UM47-1.2	C2088G	Neutral	0.134
NOTCH3	Q9UM47-1.2	C2088H	Neutral	0.137
NOTCH3	Q9UM47-1.2	C2088I	Neutral	0.007
NOTCH3	Q9UM47-1.2	C2088K	Neutral	0.13
NOTCH3	Q9UM47-1.2	C2088L	Neutral	0.007
NOTCH3	Q9UM47-1.2	C2088M	Neutral	0.007
NOTCH3	Q9UM47-1.2	C2088N	Neutral	0.148
NOTCH3	Q9UM47-1.2	C2088P	Neutral	0.149
NOTCH3	Q9UM47-1.2	C2088Q	Neutral	0.139
NOTCH3	Q9UM47-1.2	C2088R	Neutral	0.125
NOTCH3	Q9UM47-1.2	C2088S	Neutral	0.008
NOTCH3	Q9UM47-1.2	C2088T	Neutral	0.008
NOTCH3	Q9UM47-1.2	C2088V	Neutral	0.008
NOTCH3	Q9UM47-1.2	C2088W	Neutral	0.029
NOTCH3	Q9UM47-1.2	C2088Y	Neutral	0.031
NOTCH3	Q9UM47-1.2	P2089A	Neutral	0.011
NOTCH3	Q9UM47-1.2	P2089C	Neutral	0.193
NOTCH3	Q9UM47-1.2	P2089D	Neutral	0.012
NOTCH3	Q9UM47-1.2	P2089E	Neutral	0.011
NOTCH3	Q9UM47-1.2	P2089F	Neutral	0.484
NOTCH3	Q9UM47-1.2	P2089G	Neutral	0.044
NOTCH3	Q9UM47-1.2	P2089H	Neutral	0.046
NOTCH3	Q9UM47-1.2	P2089I	Neutral	0.177
NOTCH3	Q9UM47-1.2	P2089K	Neutral	0.01
NOTCH3	Q9UM47-1.2	P2089L	Neutral	0.177
NOTCH3	Q9UM47-1.2	P2089M	Neutral	0.045
NOTCH3	Q9UM47-1.2	P2089N	Neutral	0.05
NOTCH3	Q9UM47-1.2	P2089Q	Neutral	0.011
NOTCH3	Q9UM47-1.2	P2089R	Neutral	0.041
NOTCH3	Q9UM47-1.2	P2089S	Neutral	0.011
NOTCH3	Q9UM47-1.2	P2089T	Neutral	0.011
NOTCH3	Q9UM47-1.2	P2089V	Neutral	0.048
NOTCH3	Q9UM47-1.2	P2089W	Neutral	0.458
NOTCH3	Q9UM47-1.2	P2089Y	Neutral	0.167
NOTCH3	Q9UM47-1.2	G2090A	Neutral	0.043
NOTCH3	Q9UM47-1.2	G2090C	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	G2090D	Neutral	0.156
NOTCH3	Q9UM47-1.2	G2090E	Neutral	0.44
NOTCH3	Q9UM47-1.2	G2090F	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	G2090H	Neutral	0.431
NOTCH3	Q9UM47-1.2	G2090I	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	G2090K	Neutral	0.416
NOTCH3	Q9UM47-1.2	G2090L	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	G2090M	Pathogenic	0.772
NOTCH3	Q9UM47-1.2	G2090N	Neutral	0.038
NOTCH3	Q9UM47-1.2	G2090P	Neutral	0.458
NOTCH3	Q9UM47-1.2	G2090Q	Neutral	0.434
NOTCH3	Q9UM47-1.2	G2090R	Neutral	0.404
NOTCH3	Q9UM47-1.2	G2090S	Neutral	0.042
NOTCH3	Q9UM47-1.2	G2090T	Neutral	0.455
NOTCH3	Q9UM47-1.2	G2090V	Pathogenic	0.785
NOTCH3	Q9UM47-1.2	G2090W	Neutral	0.393
NOTCH3	Q9UM47-1.2	G2090Y	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	P2091A	Neutral	0.016
NOTCH3	Q9UM47-1.2	P2091C	Neutral	0.26
NOTCH3	Q9UM47-1.2	P2091D	Neutral	0.017
NOTCH3	Q9UM47-1.2	P2091E	Neutral	0.016
NOTCH3	Q9UM47-1.2	P2091F	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	P2091G	Neutral	0.063
NOTCH3	Q9UM47-1.2	P2091H	Neutral	0.066
NOTCH3	Q9UM47-1.2	P2091I	Neutral	0.24
NOTCH3	Q9UM47-1.2	P2091K	Neutral	0.014
NOTCH3	Q9UM47-1.2	P2091L	Neutral	0.24
NOTCH3	Q9UM47-1.2	P2091M	Neutral	0.065
NOTCH3	Q9UM47-1.2	P2091N	Neutral	0.072
NOTCH3	Q9UM47-1.2	P2091Q	Neutral	0.016
NOTCH3	Q9UM47-1.2	P2091R	Neutral	0.06
NOTCH3	Q9UM47-1.2	P2091S	Neutral	0.016
NOTCH3	Q9UM47-1.2	P2091T	Neutral	0.017
NOTCH3	Q9UM47-1.2	P2091V	Neutral	0.069
NOTCH3	Q9UM47-1.2	P2091W	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	P2091Y	Neutral	0.227
NOTCH3	Q9UM47-1.2	L2092A	Neutral	0.432
NOTCH3	Q9UM47-1.2	L2092C	Neutral	0.449
NOTCH3	Q9UM47-1.2	L2092D	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	L2092E	Pathogenic	0.949
NOTCH3	Q9UM47-1.2	L2092F	Neutral	0.165
NOTCH3	Q9UM47-1.2	L2092G	Pathogenic	0.985
NOTCH3	Q9UM47-1.2	L2092H	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	L2092I	Neutral	0.01
NOTCH3	Q9UM47-1.2	L2092K	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	L2092M	Neutral	0.01
NOTCH3	Q9UM47-1.2	L2092N	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	L2092P	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	L2092Q	Pathogenic	0.807
NOTCH3	Q9UM47-1.2	L2092R	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	L2092S	Pathogenic	0.781
NOTCH3	Q9UM47-1.2	L2092T	Neutral	0.457
NOTCH3	Q9UM47-1.2	L2092V	Neutral	0.041
NOTCH3	Q9UM47-1.2	L2092W	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	L2092Y	Neutral	0.469
NOTCH3	Q9UM47-1.2	A2093C	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2093D	Neutral	0.072
NOTCH3	Q9UM47-1.2	A2093E	Neutral	0.016
NOTCH3	Q9UM47-1.2	A2093F	Neutral	0.061
NOTCH3	Q9UM47-1.2	A2093G	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2093H	Neutral	0.065
NOTCH3	Q9UM47-1.2	A2093I	Neutral	0.015
NOTCH3	Q9UM47-1.2	A2093K	Neutral	0.014
NOTCH3	Q9UM47-1.2	A2093L	Neutral	0.015
NOTCH3	Q9UM47-1.2	A2093M	Neutral	0.015
NOTCH3	Q9UM47-1.2	A2093N	Neutral	0.07
NOTCH3	Q9UM47-1.2	A2093P	Neutral	0.017
NOTCH3	Q9UM47-1.2	A2093Q	Neutral	0.015
NOTCH3	Q9UM47-1.2	A2093R	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2093S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2093T	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2093V	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2093W	Neutral	0.211
NOTCH3	Q9UM47-1.2	A2093Y	Neutral	0.06
NOTCH3	Q9UM47-1.2	D2094A	Neutral	0.47
NOTCH3	Q9UM47-1.2	D2094C	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	D2094E	Neutral	0.002
NOTCH3	Q9UM47-1.2	D2094F	Pathogenic	0.791
NOTCH3	Q9UM47-1.2	D2094G	Neutral	0.153
NOTCH3	Q9UM47-1.2	D2094H	Neutral	0.161
NOTCH3	Q9UM47-1.2	D2094I	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	D2094K	Neutral	0.152
NOTCH3	Q9UM47-1.2	D2094L	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	D2094M	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	D2094N	Neutral	0.01
NOTCH3	Q9UM47-1.2	D2094P	Neutral	0.176
NOTCH3	Q9UM47-1.2	D2094Q	Neutral	0.041
NOTCH3	Q9UM47-1.2	D2094R	Neutral	0.437
NOTCH3	Q9UM47-1.2	D2094S	Neutral	0.042
NOTCH3	Q9UM47-1.2	D2094T	Neutral	0.175
NOTCH3	Q9UM47-1.2	D2094V	Pathogenic	0.809
NOTCH3	Q9UM47-1.2	D2094W	Pathogenic	0.94
NOTCH3	Q9UM47-1.2	D2094Y	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	S2095A	Neutral	0.024
NOTCH3	Q9UM47-1.2	S2095C	Neutral	0.332
NOTCH3	Q9UM47-1.2	S2095D	Neutral	0.097
NOTCH3	Q9UM47-1.2	S2095E	Neutral	0.091
NOTCH3	Q9UM47-1.2	S2095F	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	S2095G	Neutral	0.094
NOTCH3	Q9UM47-1.2	S2095H	Neutral	0.304
NOTCH3	Q9UM47-1.2	S2095I	Pathogenic	0.663
NOTCH3	Q9UM47-1.2	S2095K	Neutral	0.083
NOTCH3	Q9UM47-1.2	S2095L	Pathogenic	0.663
NOTCH3	Q9UM47-1.2	S2095M	Neutral	0.301
NOTCH3	Q9UM47-1.2	S2095N	Neutral	0.022
NOTCH3	Q9UM47-1.2	S2095P	Neutral	0.328
NOTCH3	Q9UM47-1.2	S2095Q	Neutral	0.089
NOTCH3	Q9UM47-1.2	S2095R	Neutral	0.281
NOTCH3	Q9UM47-1.2	S2095T	Neutral	0.023
NOTCH3	Q9UM47-1.2	S2095V	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	S2095W	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	S2095Y	Pathogenic	0.647
NOTCH3	Q9UM47-1.2	S2096A	Neutral	0.041
NOTCH3	Q9UM47-1.2	S2096C	Neutral	0.463
NOTCH3	Q9UM47-1.2	S2096D	Neutral	0.156
NOTCH3	Q9UM47-1.2	S2096E	Neutral	0.147
NOTCH3	Q9UM47-1.2	S2096F	Pathogenic	0.766
NOTCH3	Q9UM47-1.2	S2096G	Neutral	0.152
NOTCH3	Q9UM47-1.2	S2096H	Neutral	0.43
NOTCH3	Q9UM47-1.2	S2096I	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	S2096K	Neutral	0.135
NOTCH3	Q9UM47-1.2	S2096L	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	S2096M	Neutral	0.427
NOTCH3	Q9UM47-1.2	S2096N	Neutral	0.038
NOTCH3	Q9UM47-1.2	S2096P	Neutral	0.458
NOTCH3	Q9UM47-1.2	S2096Q	Neutral	0.144
NOTCH3	Q9UM47-1.2	S2096R	Neutral	0.404
NOTCH3	Q9UM47-1.2	S2096T	Neutral	0.039
NOTCH3	Q9UM47-1.2	S2096V	Pathogenic	0.785
NOTCH3	Q9UM47-1.2	S2096W	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	S2096Y	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	V2097A	Neutral	0.071
NOTCH3	Q9UM47-1.2	V2097C	Neutral	0.27
NOTCH3	Q9UM47-1.2	V2097D	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	V2097E	Pathogenic	0.644
NOTCH3	Q9UM47-1.2	V2097F	Neutral	0.262
NOTCH3	Q9UM47-1.2	V2097G	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	V2097H	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	V2097I	Neutral	0.001
NOTCH3	Q9UM47-1.2	V2097K	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	V2097L	Neutral	0.018
NOTCH3	Q9UM47-1.2	V2097M	Neutral	0.018
NOTCH3	Q9UM47-1.2	V2097N	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	V2097P	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	V2097Q	Pathogenic	0.639
NOTCH3	Q9UM47-1.2	V2097R	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	V2097S	Pathogenic	0.618
NOTCH3	Q9UM47-1.2	V2097T	Neutral	0.078
NOTCH3	Q9UM47-1.2	V2097W	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	V2097Y	Neutral	0.258
NOTCH3	Q9UM47-1.2	T2098A	Neutral	0.055
NOTCH3	Q9UM47-1.2	T2098C	Neutral	0.224
NOTCH3	Q9UM47-1.2	T2098D	Neutral	0.227
NOTCH3	Q9UM47-1.2	T2098E	Neutral	0.218
NOTCH3	Q9UM47-1.2	T2098F	Pathogenic	0.535
NOTCH3	Q9UM47-1.2	T2098G	Pathogenic	0.53
NOTCH3	Q9UM47-1.2	T2098H	Pathogenic	0.549
NOTCH3	Q9UM47-1.2	T2098I	Neutral	0.209
NOTCH3	Q9UM47-1.2	T2098K	Neutral	0.202
NOTCH3	Q9UM47-1.2	T2098L	Neutral	0.209
NOTCH3	Q9UM47-1.2	T2098M	Neutral	0.208
NOTCH3	Q9UM47-1.2	T2098N	Neutral	0.06
NOTCH3	Q9UM47-1.2	T2098P	Neutral	0.226
NOTCH3	Q9UM47-1.2	T2098Q	Neutral	0.214
NOTCH3	Q9UM47-1.2	T2098R	Neutral	0.194
NOTCH3	Q9UM47-1.2	T2098S	Neutral	0.013
NOTCH3	Q9UM47-1.2	T2098V	Neutral	0.059
NOTCH3	Q9UM47-1.2	T2098W	Pathogenic	0.509
NOTCH3	Q9UM47-1.2	T2098Y	Pathogenic	0.528
NOTCH3	Q9UM47-1.2	L2099A	Neutral	0.377
NOTCH3	Q9UM47-1.2	L2099C	Neutral	0.393
NOTCH3	Q9UM47-1.2	L2099D	Pathogenic	0.984
NOTCH3	Q9UM47-1.2	L2099E	Pathogenic	0.937
NOTCH3	Q9UM47-1.2	L2099F	Neutral	0.136
NOTCH3	Q9UM47-1.2	L2099G	Pathogenic	0.982
NOTCH3	Q9UM47-1.2	L2099H	Pathogenic	0.939
NOTCH3	Q9UM47-1.2	L2099I	Neutral	0.008
NOTCH3	Q9UM47-1.2	L2099K	Pathogenic	0.769
NOTCH3	Q9UM47-1.2	L2099M	Neutral	0.008
NOTCH3	Q9UM47-1.2	L2099N	Pathogenic	0.934
NOTCH3	Q9UM47-1.2	L2099P	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	L2099Q	Pathogenic	0.768
NOTCH3	Q9UM47-1.2	L2099R	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	L2099S	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	L2099T	Neutral	0.401
NOTCH3	Q9UM47-1.2	L2099V	Neutral	0.032
NOTCH3	Q9UM47-1.2	L2099W	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	L2099Y	Neutral	0.413
NOTCH3	Q9UM47-1.2	S2100A	Neutral	0.053
NOTCH3	Q9UM47-1.2	S2100C	Pathogenic	0.534
NOTCH3	Q9UM47-1.2	S2100D	Neutral	0.198
NOTCH3	Q9UM47-1.2	S2100E	Neutral	0.187
NOTCH3	Q9UM47-1.2	S2100F	Pathogenic	0.813
NOTCH3	Q9UM47-1.2	S2100G	Neutral	0.192
NOTCH3	Q9UM47-1.2	S2100H	Pathogenic	0.501
NOTCH3	Q9UM47-1.2	S2100I	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	S2100K	Neutral	0.172
NOTCH3	Q9UM47-1.2	S2100L	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	S2100M	Neutral	0.498
NOTCH3	Q9UM47-1.2	S2100N	Neutral	0.05
NOTCH3	Q9UM47-1.2	S2100P	Pathogenic	0.529
NOTCH3	Q9UM47-1.2	S2100Q	Neutral	0.183
NOTCH3	Q9UM47-1.2	S2100R	Neutral	0.474
NOTCH3	Q9UM47-1.2	S2100T	Neutral	0.051
NOTCH3	Q9UM47-1.2	S2100V	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	S2100W	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	S2100Y	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	P2101A	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	P2101C	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	P2101D	Pathogenic	0.596
NOTCH3	Q9UM47-1.2	P2101E	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	P2101F	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	P2101G	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	P2101H	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	P2101I	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	P2101K	Pathogenic	0.555
NOTCH3	Q9UM47-1.2	P2101L	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	P2101M	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	P2101N	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	P2101Q	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	P2101R	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	P2101S	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	P2101T	Pathogenic	0.592
NOTCH3	Q9UM47-1.2	P2101V	Pathogenic	0.863
NOTCH3	Q9UM47-1.2	P2101W	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	P2101Y	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	V2102A	Neutral	0.352
NOTCH3	Q9UM47-1.2	V2102C	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	V2102D	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	V2102E	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	V2102F	Pathogenic	0.718
NOTCH3	Q9UM47-1.2	V2102G	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	V2102H	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	V2102I	Neutral	0.006
NOTCH3	Q9UM47-1.2	V2102K	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	V2102L	Neutral	0.113
NOTCH3	Q9UM47-1.2	V2102M	Neutral	0.113
NOTCH3	Q9UM47-1.2	V2102N	Pathogenic	0.983
NOTCH3	Q9UM47-1.2	V2102P	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	V2102Q	Pathogenic	0.927
NOTCH3	Q9UM47-1.2	V2102R	Pathogenic	0.981
NOTCH3	Q9UM47-1.2	V2102S	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	V2102T	Neutral	0.375
NOTCH3	Q9UM47-1.2	V2102W	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	V2102Y	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	D2103A	Pathogenic	0.823
NOTCH3	Q9UM47-1.2	D2103C	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	D2103E	Neutral	0.011
NOTCH3	Q9UM47-1.2	D2103F	Pathogenic	0.952
NOTCH3	Q9UM47-1.2	D2103G	Neutral	0.486
NOTCH3	Q9UM47-1.2	D2103H	Pathogenic	0.501
NOTCH3	Q9UM47-1.2	D2103I	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	D2103K	Neutral	0.483
NOTCH3	Q9UM47-1.2	D2103L	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	D2103M	Pathogenic	0.954
NOTCH3	Q9UM47-1.2	D2103N	Neutral	0.05
NOTCH3	Q9UM47-1.2	D2103P	Pathogenic	0.527
NOTCH3	Q9UM47-1.2	D2103Q	Neutral	0.183
NOTCH3	Q9UM47-1.2	D2103R	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	D2103S	Neutral	0.186
NOTCH3	Q9UM47-1.2	D2103T	Pathogenic	0.526
NOTCH3	Q9UM47-1.2	D2103V	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	D2103W	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	D2103Y	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	S2104A	Neutral	0.069
NOTCH3	Q9UM47-1.2	S2104C	Pathogenic	0.6
NOTCH3	Q9UM47-1.2	S2104D	Neutral	0.244
NOTCH3	Q9UM47-1.2	S2104E	Neutral	0.231
NOTCH3	Q9UM47-1.2	S2104F	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	S2104G	Neutral	0.238
NOTCH3	Q9UM47-1.2	S2104H	Pathogenic	0.568
NOTCH3	Q9UM47-1.2	S2104I	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	S2104K	Neutral	0.214
NOTCH3	Q9UM47-1.2	S2104L	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	S2104M	Pathogenic	0.565
NOTCH3	Q9UM47-1.2	S2104N	Neutral	0.065
NOTCH3	Q9UM47-1.2	S2104P	Pathogenic	0.596
NOTCH3	Q9UM47-1.2	S2104Q	Neutral	0.227
NOTCH3	Q9UM47-1.2	S2104R	Pathogenic	0.541
NOTCH3	Q9UM47-1.2	S2104T	Neutral	0.065
NOTCH3	Q9UM47-1.2	S2104V	Pathogenic	0.864
NOTCH3	Q9UM47-1.2	S2104W	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	S2104Y	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	L2105A	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	L2105C	Pathogenic	0.565
NOTCH3	Q9UM47-1.2	L2105D	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	L2105E	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	L2105F	Neutral	0.24
NOTCH3	Q9UM47-1.2	L2105G	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	L2105H	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	L2105I	Neutral	0.016
NOTCH3	Q9UM47-1.2	L2105K	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	L2105M	Neutral	0.016
NOTCH3	Q9UM47-1.2	L2105N	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	L2105P	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	L2105Q	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	L2105R	Pathogenic	0.864
NOTCH3	Q9UM47-1.2	L2105S	Pathogenic	0.85
NOTCH3	Q9UM47-1.2	L2105T	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	L2105V	Neutral	0.063
NOTCH3	Q9UM47-1.2	L2105W	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	L2105Y	Pathogenic	0.585
NOTCH3	Q9UM47-1.2	D2106A	Neutral	0.253
NOTCH3	Q9UM47-1.2	D2106C	Pathogenic	0.625
NOTCH3	Q9UM47-1.2	D2106E	Neutral	0.001
NOTCH3	Q9UM47-1.2	D2106F	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	D2106G	Neutral	0.065
NOTCH3	Q9UM47-1.2	D2106H	Neutral	0.068
NOTCH3	Q9UM47-1.2	D2106I	Pathogenic	0.601
NOTCH3	Q9UM47-1.2	D2106K	Neutral	0.064
NOTCH3	Q9UM47-1.2	D2106L	Pathogenic	0.873
NOTCH3	Q9UM47-1.2	D2106M	Pathogenic	0.6
NOTCH3	Q9UM47-1.2	D2106N	Neutral	0.004
NOTCH3	Q9UM47-1.2	D2106P	Neutral	0.075
NOTCH3	Q9UM47-1.2	D2106Q	Neutral	0.016
NOTCH3	Q9UM47-1.2	D2106R	Neutral	0.229
NOTCH3	Q9UM47-1.2	D2106S	Neutral	0.016
NOTCH3	Q9UM47-1.2	D2106T	Neutral	0.075
NOTCH3	Q9UM47-1.2	D2106V	Pathogenic	0.618
NOTCH3	Q9UM47-1.2	D2106W	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	D2106Y	Pathogenic	0.584
NOTCH3	Q9UM47-1.2	S2107A	Neutral	0.068
NOTCH3	Q9UM47-1.2	S2107C	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	S2107D	Neutral	0.242
NOTCH3	Q9UM47-1.2	S2107E	Neutral	0.229
NOTCH3	Q9UM47-1.2	S2107F	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	S2107G	Neutral	0.236
NOTCH3	Q9UM47-1.2	S2107H	Pathogenic	0.565
NOTCH3	Q9UM47-1.2	S2107I	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	S2107K	Neutral	0.212
NOTCH3	Q9UM47-1.2	S2107L	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	S2107M	Pathogenic	0.562
NOTCH3	Q9UM47-1.2	S2107N	Neutral	0.064
NOTCH3	Q9UM47-1.2	S2107P	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	S2107Q	Neutral	0.225
NOTCH3	Q9UM47-1.2	S2107R	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	S2107T	Neutral	0.065
NOTCH3	Q9UM47-1.2	S2107V	Pathogenic	0.863
NOTCH3	Q9UM47-1.2	S2107W	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	S2107Y	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	P2108A	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	P2108C	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	P2108D	Pathogenic	0.62
NOTCH3	Q9UM47-1.2	P2108E	Pathogenic	0.603
NOTCH3	Q9UM47-1.2	P2108F	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	P2108G	Pathogenic	0.863
NOTCH3	Q9UM47-1.2	P2108H	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	P2108I	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	P2108K	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	P2108L	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	P2108M	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	P2108N	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	P2108Q	Pathogenic	0.598
NOTCH3	Q9UM47-1.2	P2108R	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	P2108S	Pathogenic	0.604
NOTCH3	Q9UM47-1.2	P2108T	Pathogenic	0.616
NOTCH3	Q9UM47-1.2	P2108V	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	P2108W	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	P2108Y	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	R2109A	Neutral	0.054
NOTCH3	Q9UM47-1.2	R2109C	Pathogenic	0.564
NOTCH3	Q9UM47-1.2	R2109D	Neutral	0.222
NOTCH3	Q9UM47-1.2	R2109E	Neutral	0.015
NOTCH3	Q9UM47-1.2	R2109F	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	R2109G	Neutral	0.196
NOTCH3	Q9UM47-1.2	R2109H	Neutral	0.015
NOTCH3	Q9UM47-1.2	R2109I	Pathogenic	0.601
NOTCH3	Q9UM47-1.2	R2109K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R2109L	Neutral	0.248
NOTCH3	Q9UM47-1.2	R2109M	Neutral	0.067
NOTCH3	Q9UM47-1.2	R2109N	Neutral	0.014
NOTCH3	Q9UM47-1.2	R2109P	Neutral	0.223
NOTCH3	Q9UM47-1.2	R2109Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	R2109S	Neutral	0.056
NOTCH3	Q9UM47-1.2	R2109T	Neutral	0.06
NOTCH3	Q9UM47-1.2	R2109V	Pathogenic	0.582
NOTCH3	Q9UM47-1.2	R2109W	Pathogenic	0.61
NOTCH3	Q9UM47-1.2	R2109Y	Neutral	0.26
NOTCH3	Q9UM47-1.2	P2110A	Neutral	0.01
NOTCH3	Q9UM47-1.2	P2110C	Neutral	0.178
NOTCH3	Q9UM47-1.2	P2110D	Neutral	0.011
NOTCH3	Q9UM47-1.2	P2110E	Neutral	0.01
NOTCH3	Q9UM47-1.2	P2110F	Neutral	0.458
NOTCH3	Q9UM47-1.2	P2110G	Neutral	0.039
NOTCH3	Q9UM47-1.2	P2110H	Neutral	0.042
NOTCH3	Q9UM47-1.2	P2110I	Neutral	0.162
NOTCH3	Q9UM47-1.2	P2110K	Neutral	0.009
NOTCH3	Q9UM47-1.2	P2110L	Neutral	0.162
NOTCH3	Q9UM47-1.2	P2110M	Neutral	0.041
NOTCH3	Q9UM47-1.2	P2110N	Neutral	0.045
NOTCH3	Q9UM47-1.2	P2110Q	Neutral	0.01
NOTCH3	Q9UM47-1.2	P2110R	Neutral	0.038
NOTCH3	Q9UM47-1.2	P2110S	Neutral	0.01
NOTCH3	Q9UM47-1.2	P2110T	Neutral	0.01
NOTCH3	Q9UM47-1.2	P2110V	Neutral	0.044
NOTCH3	Q9UM47-1.2	P2110W	Neutral	0.432
NOTCH3	Q9UM47-1.2	P2110Y	Neutral	0.153
NOTCH3	Q9UM47-1.2	F2111A	Pathogenic	0.568
NOTCH3	Q9UM47-1.2	F2111C	Pathogenic	0.585
NOTCH3	Q9UM47-1.2	F2111D	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	F2111E	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	F2111G	Pathogenic	0.848
NOTCH3	Q9UM47-1.2	F2111H	Neutral	0.261
NOTCH3	Q9UM47-1.2	F2111I	Neutral	0.073
NOTCH3	Q9UM47-1.2	F2111K	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	F2111L	Neutral	0.073
NOTCH3	Q9UM47-1.2	F2111M	Neutral	0.073
NOTCH3	Q9UM47-1.2	F2111N	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	F2111P	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	F2111Q	Pathogenic	0.878
NOTCH3	Q9UM47-1.2	F2111R	Pathogenic	0.882
NOTCH3	Q9UM47-1.2	F2111S	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	F2111T	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	F2111V	Neutral	0.25
NOTCH3	Q9UM47-1.2	F2111W	Neutral	0.016
NOTCH3	Q9UM47-1.2	F2111Y	Neutral	0.001
NOTCH3	Q9UM47-1.2	G2112A	Neutral	0.001
NOTCH3	Q9UM47-1.2	G2112C	Neutral	0.087
NOTCH3	Q9UM47-1.2	G2112D	Neutral	0.004
NOTCH3	Q9UM47-1.2	G2112E	Neutral	0.019
NOTCH3	Q9UM47-1.2	G2112F	Neutral	0.074
NOTCH3	Q9UM47-1.2	G2112H	Neutral	0.018
NOTCH3	Q9UM47-1.2	G2112I	Neutral	0.274
NOTCH3	Q9UM47-1.2	G2112K	Neutral	0.017
NOTCH3	Q9UM47-1.2	G2112L	Neutral	0.274
NOTCH3	Q9UM47-1.2	G2112M	Neutral	0.076
NOTCH3	Q9UM47-1.2	G2112N	Neutral	0.001
NOTCH3	Q9UM47-1.2	G2112P	Neutral	0.02
NOTCH3	Q9UM47-1.2	G2112Q	Neutral	0.018
NOTCH3	Q9UM47-1.2	G2112R	Neutral	0.016
NOTCH3	Q9UM47-1.2	G2112S	Neutral	0.001
NOTCH3	Q9UM47-1.2	G2112T	Neutral	0.02
NOTCH3	Q9UM47-1.2	G2112V	Neutral	0.082
NOTCH3	Q9UM47-1.2	G2112W	Neutral	0.015
NOTCH3	Q9UM47-1.2	G2112Y	Neutral	0.072
NOTCH3	Q9UM47-1.2	G2113A	Neutral	0.005
NOTCH3	Q9UM47-1.2	G2113C	Neutral	0.315
NOTCH3	Q9UM47-1.2	G2113D	Neutral	0.021
NOTCH3	Q9UM47-1.2	G2113E	Neutral	0.084
NOTCH3	Q9UM47-1.2	G2113F	Neutral	0.277
NOTCH3	Q9UM47-1.2	G2113H	Neutral	0.081
NOTCH3	Q9UM47-1.2	G2113I	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	G2113K	Neutral	0.077
NOTCH3	Q9UM47-1.2	G2113L	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	G2113M	Neutral	0.285
NOTCH3	Q9UM47-1.2	G2113N	Neutral	0.005
NOTCH3	Q9UM47-1.2	G2113P	Neutral	0.09
NOTCH3	Q9UM47-1.2	G2113Q	Neutral	0.083
NOTCH3	Q9UM47-1.2	G2113R	Neutral	0.074
NOTCH3	Q9UM47-1.2	G2113S	Neutral	0.005
NOTCH3	Q9UM47-1.2	G2113T	Neutral	0.089
NOTCH3	Q9UM47-1.2	G2113V	Neutral	0.3
NOTCH3	Q9UM47-1.2	G2113W	Neutral	0.07
NOTCH3	Q9UM47-1.2	G2113Y	Neutral	0.271
NOTCH3	Q9UM47-1.2	P2114A	Neutral	0.014
NOTCH3	Q9UM47-1.2	P2114C	Neutral	0.241
NOTCH3	Q9UM47-1.2	P2114D	Neutral	0.015
NOTCH3	Q9UM47-1.2	P2114E	Neutral	0.014
NOTCH3	Q9UM47-1.2	P2114F	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	P2114G	Neutral	0.057
NOTCH3	Q9UM47-1.2	P2114H	Neutral	0.06
NOTCH3	Q9UM47-1.2	P2114I	Neutral	0.222
NOTCH3	Q9UM47-1.2	P2114K	Neutral	0.013
NOTCH3	Q9UM47-1.2	P2114L	Neutral	0.222
NOTCH3	Q9UM47-1.2	P2114M	Neutral	0.059
NOTCH3	Q9UM47-1.2	P2114N	Neutral	0.065
NOTCH3	Q9UM47-1.2	P2114Q	Neutral	0.014
NOTCH3	Q9UM47-1.2	P2114R	Neutral	0.054
NOTCH3	Q9UM47-1.2	P2114S	Neutral	0.014
NOTCH3	Q9UM47-1.2	P2114T	Neutral	0.015
NOTCH3	Q9UM47-1.2	P2114V	Neutral	0.063
NOTCH3	Q9UM47-1.2	P2114W	Pathogenic	0.528
NOTCH3	Q9UM47-1.2	P2114Y	Neutral	0.209
NOTCH3	Q9UM47-1.2	P2115A	Neutral	0.042
NOTCH3	Q9UM47-1.2	P2115C	Neutral	0.495
NOTCH3	Q9UM47-1.2	P2115D	Neutral	0.046
NOTCH3	Q9UM47-1.2	P2115E	Neutral	0.043
NOTCH3	Q9UM47-1.2	P2115F	Pathogenic	0.793
NOTCH3	Q9UM47-1.2	P2115G	Neutral	0.157
NOTCH3	Q9UM47-1.2	P2115H	Neutral	0.164
NOTCH3	Q9UM47-1.2	P2115I	Neutral	0.468
NOTCH3	Q9UM47-1.2	P2115K	Neutral	0.039
NOTCH3	Q9UM47-1.2	P2115L	Neutral	0.468
NOTCH3	Q9UM47-1.2	P2115M	Neutral	0.161
NOTCH3	Q9UM47-1.2	P2115N	Neutral	0.177
NOTCH3	Q9UM47-1.2	P2115Q	Neutral	0.042
NOTCH3	Q9UM47-1.2	P2115R	Neutral	0.15
NOTCH3	Q9UM47-1.2	P2115S	Neutral	0.043
NOTCH3	Q9UM47-1.2	P2115T	Neutral	0.045
NOTCH3	Q9UM47-1.2	P2115V	Neutral	0.171
NOTCH3	Q9UM47-1.2	P2115W	Pathogenic	0.776
NOTCH3	Q9UM47-1.2	P2115Y	Neutral	0.45
NOTCH3	Q9UM47-1.2	A2116C	Neutral	0.042
NOTCH3	Q9UM47-1.2	A2116D	Neutral	0.473
NOTCH3	Q9UM47-1.2	A2116E	Neutral	0.155
NOTCH3	Q9UM47-1.2	A2116F	Neutral	0.432
NOTCH3	Q9UM47-1.2	A2116G	Neutral	0.042
NOTCH3	Q9UM47-1.2	A2116H	Neutral	0.445
NOTCH3	Q9UM47-1.2	A2116I	Neutral	0.148
NOTCH3	Q9UM47-1.2	A2116K	Neutral	0.143
NOTCH3	Q9UM47-1.2	A2116L	Neutral	0.148
NOTCH3	Q9UM47-1.2	A2116M	Neutral	0.148
NOTCH3	Q9UM47-1.2	A2116N	Neutral	0.468
NOTCH3	Q9UM47-1.2	A2116P	Neutral	0.164
NOTCH3	Q9UM47-1.2	A2116Q	Neutral	0.152
NOTCH3	Q9UM47-1.2	A2116R	Neutral	0.137
NOTCH3	Q9UM47-1.2	A2116S	Neutral	0.01
NOTCH3	Q9UM47-1.2	A2116T	Neutral	0.041
NOTCH3	Q9UM47-1.2	A2116V	Neutral	0.039
NOTCH3	Q9UM47-1.2	A2116W	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	A2116Y	Neutral	0.424
NOTCH3	Q9UM47-1.2	S2117A	Neutral	0.038
NOTCH3	Q9UM47-1.2	S2117C	Neutral	0.443
NOTCH3	Q9UM47-1.2	S2117D	Neutral	0.146
NOTCH3	Q9UM47-1.2	S2117E	Neutral	0.137
NOTCH3	Q9UM47-1.2	S2117F	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	S2117G	Neutral	0.142
NOTCH3	Q9UM47-1.2	S2117H	Neutral	0.411
NOTCH3	Q9UM47-1.2	S2117I	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	S2117K	Neutral	0.126
NOTCH3	Q9UM47-1.2	S2117L	Pathogenic	0.759
NOTCH3	Q9UM47-1.2	S2117M	Neutral	0.407
NOTCH3	Q9UM47-1.2	S2117N	Neutral	0.035
NOTCH3	Q9UM47-1.2	S2117P	Neutral	0.438
NOTCH3	Q9UM47-1.2	S2117Q	Neutral	0.135
NOTCH3	Q9UM47-1.2	S2117R	Neutral	0.385
NOTCH3	Q9UM47-1.2	S2117T	Neutral	0.036
NOTCH3	Q9UM47-1.2	S2117V	Pathogenic	0.771
NOTCH3	Q9UM47-1.2	S2117W	Pathogenic	0.925
NOTCH3	Q9UM47-1.2	S2117Y	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	P2118A	Neutral	0.242
NOTCH3	Q9UM47-1.2	P2118C	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	P2118D	Neutral	0.26
NOTCH3	Q9UM47-1.2	P2118E	Neutral	0.247
NOTCH3	Q9UM47-1.2	P2118F	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	P2118G	Pathogenic	0.576
NOTCH3	Q9UM47-1.2	P2118H	Pathogenic	0.589
NOTCH3	Q9UM47-1.2	P2118I	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	P2118K	Neutral	0.229
NOTCH3	Q9UM47-1.2	P2118L	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	P2118M	Pathogenic	0.583
NOTCH3	Q9UM47-1.2	P2118N	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	P2118Q	Neutral	0.243
NOTCH3	Q9UM47-1.2	P2118R	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	P2118S	Neutral	0.247
NOTCH3	Q9UM47-1.2	P2118T	Neutral	0.257
NOTCH3	Q9UM47-1.2	P2118V	Pathogenic	0.601
NOTCH3	Q9UM47-1.2	P2118W	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	P2118Y	Pathogenic	0.856
NOTCH3	Q9UM47-1.2	G2119A	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2119C	Neutral	0.226
NOTCH3	Q9UM47-1.2	G2119D	Neutral	0.014
NOTCH3	Q9UM47-1.2	G2119E	Neutral	0.055
NOTCH3	Q9UM47-1.2	G2119F	Neutral	0.196
NOTCH3	Q9UM47-1.2	G2119H	Neutral	0.053
NOTCH3	Q9UM47-1.2	G2119I	Pathogenic	0.537
NOTCH3	Q9UM47-1.2	G2119K	Neutral	0.051
NOTCH3	Q9UM47-1.2	G2119L	Pathogenic	0.536
NOTCH3	Q9UM47-1.2	G2119M	Neutral	0.202
NOTCH3	Q9UM47-1.2	G2119N	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2119P	Neutral	0.059
NOTCH3	Q9UM47-1.2	G2119Q	Neutral	0.054
NOTCH3	Q9UM47-1.2	G2119R	Neutral	0.048
NOTCH3	Q9UM47-1.2	G2119S	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2119T	Neutral	0.059
NOTCH3	Q9UM47-1.2	G2119V	Neutral	0.214
NOTCH3	Q9UM47-1.2	G2119W	Neutral	0.046
NOTCH3	Q9UM47-1.2	G2119Y	Neutral	0.191
NOTCH3	Q9UM47-1.2	G2120A	Neutral	0.001
NOTCH3	Q9UM47-1.2	G2120C	Neutral	0.072
NOTCH3	Q9UM47-1.2	G2120D	Neutral	0.004
NOTCH3	Q9UM47-1.2	G2120E	Neutral	0.015
NOTCH3	Q9UM47-1.2	G2120F	Neutral	0.061
NOTCH3	Q9UM47-1.2	G2120H	Neutral	0.015
NOTCH3	Q9UM47-1.2	G2120I	Neutral	0.235
NOTCH3	Q9UM47-1.2	G2120K	Neutral	0.014
NOTCH3	Q9UM47-1.2	G2120L	Neutral	0.235
NOTCH3	Q9UM47-1.2	G2120M	Neutral	0.063
NOTCH3	Q9UM47-1.2	G2120N	Neutral	0.001
NOTCH3	Q9UM47-1.2	G2120P	Neutral	0.016
NOTCH3	Q9UM47-1.2	G2120Q	Neutral	0.015
NOTCH3	Q9UM47-1.2	G2120R	Neutral	0.013
NOTCH3	Q9UM47-1.2	G2120S	Neutral	0.001
NOTCH3	Q9UM47-1.2	G2120T	Neutral	0.016
NOTCH3	Q9UM47-1.2	G2120V	Neutral	0.067
NOTCH3	Q9UM47-1.2	G2120W	Neutral	0.013
NOTCH3	Q9UM47-1.2	G2120Y	Neutral	0.059
NOTCH3	Q9UM47-1.2	F2121A	Neutral	0.249
NOTCH3	Q9UM47-1.2	F2121C	Neutral	0.262
NOTCH3	Q9UM47-1.2	F2121D	Pathogenic	0.626
NOTCH3	Q9UM47-1.2	F2121E	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	F2121G	Pathogenic	0.585
NOTCH3	Q9UM47-1.2	F2121H	Neutral	0.082
NOTCH3	Q9UM47-1.2	F2121I	Neutral	0.019
NOTCH3	Q9UM47-1.2	F2121K	Pathogenic	0.665
NOTCH3	Q9UM47-1.2	F2121L	Neutral	0.019
NOTCH3	Q9UM47-1.2	F2121M	Neutral	0.019
NOTCH3	Q9UM47-1.2	F2121N	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	F2121P	Pathogenic	0.882
NOTCH3	Q9UM47-1.2	F2121Q	Pathogenic	0.646
NOTCH3	Q9UM47-1.2	F2121R	Pathogenic	0.654
NOTCH3	Q9UM47-1.2	F2121S	Neutral	0.254
NOTCH3	Q9UM47-1.2	F2121T	Neutral	0.269
NOTCH3	Q9UM47-1.2	F2121V	Neutral	0.077
NOTCH3	Q9UM47-1.2	F2121W	Neutral	0.004
NOTCH3	Q9UM47-1.2	F2121Y	Neutral	0.0
NOTCH3	Q9UM47-1.2	P2122A	Neutral	0.063
NOTCH3	Q9UM47-1.2	P2122C	Pathogenic	0.601
NOTCH3	Q9UM47-1.2	P2122D	Neutral	0.069
NOTCH3	Q9UM47-1.2	P2122E	Neutral	0.065
NOTCH3	Q9UM47-1.2	P2122F	Pathogenic	0.855
NOTCH3	Q9UM47-1.2	P2122G	Neutral	0.223
NOTCH3	Q9UM47-1.2	P2122H	Neutral	0.232
NOTCH3	Q9UM47-1.2	P2122I	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	P2122K	Neutral	0.059
NOTCH3	Q9UM47-1.2	P2122L	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	P2122M	Neutral	0.228
NOTCH3	Q9UM47-1.2	P2122N	Neutral	0.249
NOTCH3	Q9UM47-1.2	P2122Q	Neutral	0.063
NOTCH3	Q9UM47-1.2	P2122R	Neutral	0.214
NOTCH3	Q9UM47-1.2	P2122S	Neutral	0.065
NOTCH3	Q9UM47-1.2	P2122T	Neutral	0.068
NOTCH3	Q9UM47-1.2	P2122V	Neutral	0.241
NOTCH3	Q9UM47-1.2	P2122W	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	P2122Y	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	L2123A	Neutral	0.02
NOTCH3	Q9UM47-1.2	L2123C	Neutral	0.022
NOTCH3	Q9UM47-1.2	L2123D	Pathogenic	0.686
NOTCH3	Q9UM47-1.2	L2123E	Neutral	0.339
NOTCH3	Q9UM47-1.2	L2123F	Neutral	0.005
NOTCH3	Q9UM47-1.2	L2123G	Pathogenic	0.648
NOTCH3	Q9UM47-1.2	L2123H	Neutral	0.346
NOTCH3	Q9UM47-1.2	L2123I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2123K	Neutral	0.103
NOTCH3	Q9UM47-1.2	L2123M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2123N	Neutral	0.328
NOTCH3	Q9UM47-1.2	L2123P	Neutral	0.321
NOTCH3	Q9UM47-1.2	L2123Q	Neutral	0.103
NOTCH3	Q9UM47-1.2	L2123R	Neutral	0.099
NOTCH3	Q9UM47-1.2	L2123S	Neutral	0.089
NOTCH3	Q9UM47-1.2	L2123T	Neutral	0.023
NOTCH3	Q9UM47-1.2	L2123V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2123W	Neutral	0.092
NOTCH3	Q9UM47-1.2	L2123Y	Neutral	0.024
NOTCH3	Q9UM47-1.2	E2124A	Neutral	0.042
NOTCH3	Q9UM47-1.2	E2124C	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	E2124D	Neutral	0.001
NOTCH3	Q9UM47-1.2	E2124F	Neutral	0.496
NOTCH3	Q9UM47-1.2	E2124G	Neutral	0.157
NOTCH3	Q9UM47-1.2	E2124H	Neutral	0.011
NOTCH3	Q9UM47-1.2	E2124I	Pathogenic	0.506
NOTCH3	Q9UM47-1.2	E2124K	Neutral	0.002
NOTCH3	Q9UM47-1.2	E2124L	Pathogenic	0.506
NOTCH3	Q9UM47-1.2	E2124M	Neutral	0.183
NOTCH3	Q9UM47-1.2	E2124N	Neutral	0.011
NOTCH3	Q9UM47-1.2	E2124P	Neutral	0.046
NOTCH3	Q9UM47-1.2	E2124Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	E2124R	Neutral	0.01
NOTCH3	Q9UM47-1.2	E2124S	Neutral	0.01
NOTCH3	Q9UM47-1.2	E2124T	Neutral	0.046
NOTCH3	Q9UM47-1.2	E2124V	Neutral	0.19
NOTCH3	Q9UM47-1.2	E2124W	Neutral	0.47
NOTCH3	Q9UM47-1.2	E2124Y	Neutral	0.173
NOTCH3	Q9UM47-1.2	G2125A	Neutral	0.025
NOTCH3	Q9UM47-1.2	G2125C	Pathogenic	0.691
NOTCH3	Q9UM47-1.2	G2125D	Neutral	0.095
NOTCH3	Q9UM47-1.2	G2125E	Neutral	0.309
NOTCH3	Q9UM47-1.2	G2125F	Pathogenic	0.65
NOTCH3	Q9UM47-1.2	G2125H	Neutral	0.301
NOTCH3	Q9UM47-1.2	G2125I	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	G2125K	Neutral	0.289
NOTCH3	Q9UM47-1.2	G2125L	Pathogenic	0.898
NOTCH3	Q9UM47-1.2	G2125M	Pathogenic	0.659
NOTCH3	Q9UM47-1.2	G2125N	Neutral	0.022
NOTCH3	Q9UM47-1.2	G2125P	Neutral	0.325
NOTCH3	Q9UM47-1.2	G2125Q	Neutral	0.304
NOTCH3	Q9UM47-1.2	G2125R	Neutral	0.279
NOTCH3	Q9UM47-1.2	G2125S	Neutral	0.024
NOTCH3	Q9UM47-1.2	G2125T	Neutral	0.322
NOTCH3	Q9UM47-1.2	G2125V	Pathogenic	0.675
NOTCH3	Q9UM47-1.2	G2125W	Neutral	0.269
NOTCH3	Q9UM47-1.2	G2125Y	Pathogenic	0.644
NOTCH3	Q9UM47-1.2	P2126A	Neutral	0.012
NOTCH3	Q9UM47-1.2	P2126C	Neutral	0.214
NOTCH3	Q9UM47-1.2	P2126D	Neutral	0.013
NOTCH3	Q9UM47-1.2	P2126E	Neutral	0.012
NOTCH3	Q9UM47-1.2	P2126F	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	P2126G	Neutral	0.049
NOTCH3	Q9UM47-1.2	P2126H	Neutral	0.052
NOTCH3	Q9UM47-1.2	P2126I	Neutral	0.197
NOTCH3	Q9UM47-1.2	P2126K	Neutral	0.011
NOTCH3	Q9UM47-1.2	P2126L	Neutral	0.196
NOTCH3	Q9UM47-1.2	P2126M	Neutral	0.051
NOTCH3	Q9UM47-1.2	P2126N	Neutral	0.057
NOTCH3	Q9UM47-1.2	P2126Q	Neutral	0.012
NOTCH3	Q9UM47-1.2	P2126R	Neutral	0.047
NOTCH3	Q9UM47-1.2	P2126S	Neutral	0.012
NOTCH3	Q9UM47-1.2	P2126T	Neutral	0.013
NOTCH3	Q9UM47-1.2	P2126V	Neutral	0.054
NOTCH3	Q9UM47-1.2	P2126W	Neutral	0.49
NOTCH3	Q9UM47-1.2	P2126Y	Neutral	0.185
NOTCH3	Q9UM47-1.2	Y2127A	Neutral	0.382
NOTCH3	Q9UM47-1.2	Y2127C	Neutral	0.398
NOTCH3	Q9UM47-1.2	Y2127D	Pathogenic	0.757
NOTCH3	Q9UM47-1.2	Y2127E	Neutral	0.423
NOTCH3	Q9UM47-1.2	Y2127F	Neutral	0.0
NOTCH3	Q9UM47-1.2	Y2127G	Pathogenic	0.724
NOTCH3	Q9UM47-1.2	Y2127H	Neutral	0.002
NOTCH3	Q9UM47-1.2	Y2127I	Neutral	0.145
NOTCH3	Q9UM47-1.2	Y2127K	Neutral	0.448
NOTCH3	Q9UM47-1.2	Y2127L	Neutral	0.145
NOTCH3	Q9UM47-1.2	Y2127M	Neutral	0.144
NOTCH3	Q9UM47-1.2	Y2127N	Neutral	0.411
NOTCH3	Q9UM47-1.2	Y2127P	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	Y2127Q	Neutral	0.141
NOTCH3	Q9UM47-1.2	Y2127R	Neutral	0.447
NOTCH3	Q9UM47-1.2	Y2127S	Neutral	0.388
NOTCH3	Q9UM47-1.2	Y2127T	Neutral	0.406
NOTCH3	Q9UM47-1.2	Y2127V	Neutral	0.136
NOTCH3	Q9UM47-1.2	Y2127W	Neutral	0.002
NOTCH3	Q9UM47-1.2	A2128C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2128D	Neutral	0.059
NOTCH3	Q9UM47-1.2	A2128E	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2128F	Neutral	0.05
NOTCH3	Q9UM47-1.2	A2128G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2128H	Neutral	0.053
NOTCH3	Q9UM47-1.2	A2128I	Neutral	0.012
NOTCH3	Q9UM47-1.2	A2128K	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2128L	Neutral	0.012
NOTCH3	Q9UM47-1.2	A2128M	Neutral	0.012
NOTCH3	Q9UM47-1.2	A2128N	Neutral	0.058
NOTCH3	Q9UM47-1.2	A2128P	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2128Q	Neutral	0.012
NOTCH3	Q9UM47-1.2	A2128R	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2128S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2128T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2128V	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2128W	Neutral	0.178
NOTCH3	Q9UM47-1.2	A2128Y	Neutral	0.049
NOTCH3	Q9UM47-1.2	A2129C	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2129D	Neutral	0.181
NOTCH3	Q9UM47-1.2	A2129E	Neutral	0.043
NOTCH3	Q9UM47-1.2	A2129F	Neutral	0.157
NOTCH3	Q9UM47-1.2	A2129G	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2129H	Neutral	0.165
NOTCH3	Q9UM47-1.2	A2129I	Neutral	0.041
NOTCH3	Q9UM47-1.2	A2129K	Neutral	0.039
NOTCH3	Q9UM47-1.2	A2129L	Neutral	0.041
NOTCH3	Q9UM47-1.2	A2129M	Neutral	0.041
NOTCH3	Q9UM47-1.2	A2129N	Neutral	0.178
NOTCH3	Q9UM47-1.2	A2129P	Neutral	0.046
NOTCH3	Q9UM47-1.2	A2129Q	Neutral	0.042
NOTCH3	Q9UM47-1.2	A2129R	Neutral	0.037
NOTCH3	Q9UM47-1.2	A2129S	Neutral	0.002
NOTCH3	Q9UM47-1.2	A2129T	Neutral	0.01
NOTCH3	Q9UM47-1.2	A2129V	Neutral	0.01
NOTCH3	Q9UM47-1.2	A2129W	Neutral	0.434
NOTCH3	Q9UM47-1.2	A2129Y	Neutral	0.153
NOTCH3	Q9UM47-1.2	A2130C	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2130D	Neutral	0.079
NOTCH3	Q9UM47-1.2	A2130E	Neutral	0.017
NOTCH3	Q9UM47-1.2	A2130F	Neutral	0.068
NOTCH3	Q9UM47-1.2	A2130G	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2130H	Neutral	0.071
NOTCH3	Q9UM47-1.2	A2130I	Neutral	0.016
NOTCH3	Q9UM47-1.2	A2130K	Neutral	0.016
NOTCH3	Q9UM47-1.2	A2130L	Neutral	0.016
NOTCH3	Q9UM47-1.2	A2130M	Neutral	0.016
NOTCH3	Q9UM47-1.2	A2130N	Neutral	0.077
NOTCH3	Q9UM47-1.2	A2130P	Neutral	0.018
NOTCH3	Q9UM47-1.2	A2130Q	Neutral	0.017
NOTCH3	Q9UM47-1.2	A2130R	Neutral	0.015
NOTCH3	Q9UM47-1.2	A2130S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2130T	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2130V	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2130W	Neutral	0.229
NOTCH3	Q9UM47-1.2	A2130Y	Neutral	0.066
NOTCH3	Q9UM47-1.2	T2131A	Neutral	0.007
NOTCH3	Q9UM47-1.2	T2131C	Neutral	0.033
NOTCH3	Q9UM47-1.2	T2131D	Neutral	0.034
NOTCH3	Q9UM47-1.2	T2131E	Neutral	0.032
NOTCH3	Q9UM47-1.2	T2131F	Neutral	0.121
NOTCH3	Q9UM47-1.2	T2131G	Neutral	0.118
NOTCH3	Q9UM47-1.2	T2131H	Neutral	0.127
NOTCH3	Q9UM47-1.2	T2131I	Neutral	0.031
NOTCH3	Q9UM47-1.2	T2131K	Neutral	0.029
NOTCH3	Q9UM47-1.2	T2131L	Neutral	0.031
NOTCH3	Q9UM47-1.2	T2131M	Neutral	0.03
NOTCH3	Q9UM47-1.2	T2131N	Neutral	0.008
NOTCH3	Q9UM47-1.2	T2131P	Neutral	0.034
NOTCH3	Q9UM47-1.2	T2131Q	Neutral	0.031
NOTCH3	Q9UM47-1.2	T2131R	Neutral	0.028
NOTCH3	Q9UM47-1.2	T2131S	Neutral	0.002
NOTCH3	Q9UM47-1.2	T2131V	Neutral	0.007
NOTCH3	Q9UM47-1.2	T2131W	Neutral	0.11
NOTCH3	Q9UM47-1.2	T2131Y	Neutral	0.118
NOTCH3	Q9UM47-1.2	A2132C	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2132D	Neutral	0.029
NOTCH3	Q9UM47-1.2	A2132E	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2132F	Neutral	0.025
NOTCH3	Q9UM47-1.2	A2132G	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2132H	Neutral	0.026
NOTCH3	Q9UM47-1.2	A2132I	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2132K	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2132L	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2132M	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2132N	Neutral	0.028
NOTCH3	Q9UM47-1.2	A2132P	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2132Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2132R	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2132S	Neutral	0.0
NOTCH3	Q9UM47-1.2	A2132T	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2132V	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2132W	Neutral	0.094
NOTCH3	Q9UM47-1.2	A2132Y	Neutral	0.024
NOTCH3	Q9UM47-1.2	T2133A	Neutral	0.004
NOTCH3	Q9UM47-1.2	T2133C	Neutral	0.018
NOTCH3	Q9UM47-1.2	T2133D	Neutral	0.019
NOTCH3	Q9UM47-1.2	T2133E	Neutral	0.018
NOTCH3	Q9UM47-1.2	T2133F	Neutral	0.07
NOTCH3	Q9UM47-1.2	T2133G	Neutral	0.068
NOTCH3	Q9UM47-1.2	T2133H	Neutral	0.073
NOTCH3	Q9UM47-1.2	T2133I	Neutral	0.017
NOTCH3	Q9UM47-1.2	T2133K	Neutral	0.016
NOTCH3	Q9UM47-1.2	T2133L	Neutral	0.017
NOTCH3	Q9UM47-1.2	T2133M	Neutral	0.017
NOTCH3	Q9UM47-1.2	T2133N	Neutral	0.004
NOTCH3	Q9UM47-1.2	T2133P	Neutral	0.019
NOTCH3	Q9UM47-1.2	T2133Q	Neutral	0.017
NOTCH3	Q9UM47-1.2	T2133R	Neutral	0.015
NOTCH3	Q9UM47-1.2	T2133S	Neutral	0.001
NOTCH3	Q9UM47-1.2	T2133V	Neutral	0.004
NOTCH3	Q9UM47-1.2	T2133W	Neutral	0.063
NOTCH3	Q9UM47-1.2	T2133Y	Neutral	0.068
NOTCH3	Q9UM47-1.2	A2134C	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2134D	Neutral	0.086
NOTCH3	Q9UM47-1.2	A2134E	Neutral	0.019
NOTCH3	Q9UM47-1.2	A2134F	Neutral	0.074
NOTCH3	Q9UM47-1.2	A2134G	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2134H	Neutral	0.078
NOTCH3	Q9UM47-1.2	A2134I	Neutral	0.018
NOTCH3	Q9UM47-1.2	A2134K	Neutral	0.017
NOTCH3	Q9UM47-1.2	A2134L	Neutral	0.018
NOTCH3	Q9UM47-1.2	A2134M	Neutral	0.018
NOTCH3	Q9UM47-1.2	A2134N	Neutral	0.085
NOTCH3	Q9UM47-1.2	A2134P	Neutral	0.02
NOTCH3	Q9UM47-1.2	A2134Q	Neutral	0.019
NOTCH3	Q9UM47-1.2	A2134R	Neutral	0.016
NOTCH3	Q9UM47-1.2	A2134S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2134T	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2134V	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2134W	Neutral	0.247
NOTCH3	Q9UM47-1.2	A2134Y	Neutral	0.072
NOTCH3	Q9UM47-1.2	V2135A	Neutral	0.009
NOTCH3	Q9UM47-1.2	V2135C	Neutral	0.04
NOTCH3	Q9UM47-1.2	V2135D	Neutral	0.475
NOTCH3	Q9UM47-1.2	V2135E	Neutral	0.171
NOTCH3	Q9UM47-1.2	V2135F	Neutral	0.039
NOTCH3	Q9UM47-1.2	V2135G	Neutral	0.432
NOTCH3	Q9UM47-1.2	V2135H	Neutral	0.474
NOTCH3	Q9UM47-1.2	V2135I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V2135K	Neutral	0.157
NOTCH3	Q9UM47-1.2	V2135L	Neutral	0.002
NOTCH3	Q9UM47-1.2	V2135M	Neutral	0.002
NOTCH3	Q9UM47-1.2	V2135N	Neutral	0.479
NOTCH3	Q9UM47-1.2	V2135P	Neutral	0.163
NOTCH3	Q9UM47-1.2	V2135Q	Neutral	0.168
NOTCH3	Q9UM47-1.2	V2135R	Neutral	0.447
NOTCH3	Q9UM47-1.2	V2135S	Neutral	0.155
NOTCH3	Q9UM47-1.2	V2135T	Neutral	0.009
NOTCH3	Q9UM47-1.2	V2135W	Neutral	0.431
NOTCH3	Q9UM47-1.2	V2135Y	Neutral	0.038
NOTCH3	Q9UM47-1.2	S2136A	Neutral	0.002
NOTCH3	Q9UM47-1.2	S2136C	Neutral	0.041
NOTCH3	Q9UM47-1.2	S2136D	Neutral	0.009
NOTCH3	Q9UM47-1.2	S2136E	Neutral	0.009
NOTCH3	Q9UM47-1.2	S2136F	Neutral	0.14
NOTCH3	Q9UM47-1.2	S2136G	Neutral	0.009
NOTCH3	Q9UM47-1.2	S2136H	Neutral	0.036
NOTCH3	Q9UM47-1.2	S2136I	Neutral	0.145
NOTCH3	Q9UM47-1.2	S2136K	Neutral	0.008
NOTCH3	Q9UM47-1.2	S2136L	Neutral	0.145
NOTCH3	Q9UM47-1.2	S2136M	Neutral	0.036
NOTCH3	Q9UM47-1.2	S2136N	Neutral	0.002
NOTCH3	Q9UM47-1.2	S2136P	Neutral	0.04
NOTCH3	Q9UM47-1.2	S2136Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	S2136R	Neutral	0.033
NOTCH3	Q9UM47-1.2	S2136T	Neutral	0.002
NOTCH3	Q9UM47-1.2	S2136V	Neutral	0.154
NOTCH3	Q9UM47-1.2	S2136W	Neutral	0.4
NOTCH3	Q9UM47-1.2	S2136Y	Neutral	0.136
NOTCH3	Q9UM47-1.2	L2137A	Neutral	0.09
NOTCH3	Q9UM47-1.2	L2137C	Neutral	0.095
NOTCH3	Q9UM47-1.2	L2137D	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	L2137E	Pathogenic	0.708
NOTCH3	Q9UM47-1.2	L2137F	Neutral	0.025
NOTCH3	Q9UM47-1.2	L2137G	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	L2137H	Pathogenic	0.714
NOTCH3	Q9UM47-1.2	L2137I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2137K	Neutral	0.351
NOTCH3	Q9UM47-1.2	L2137M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2137N	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	L2137P	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	L2137Q	Neutral	0.351
NOTCH3	Q9UM47-1.2	L2137R	Neutral	0.34
NOTCH3	Q9UM47-1.2	L2137S	Neutral	0.315
NOTCH3	Q9UM47-1.2	L2137T	Neutral	0.098
NOTCH3	Q9UM47-1.2	L2137V	Neutral	0.005
NOTCH3	Q9UM47-1.2	L2137W	Neutral	0.323
NOTCH3	Q9UM47-1.2	L2137Y	Neutral	0.103
NOTCH3	Q9UM47-1.2	A2138C	Neutral	0.019
NOTCH3	Q9UM47-1.2	A2138D	Neutral	0.281
NOTCH3	Q9UM47-1.2	A2138E	Neutral	0.074
NOTCH3	Q9UM47-1.2	A2138F	Neutral	0.248
NOTCH3	Q9UM47-1.2	A2138G	Neutral	0.019
NOTCH3	Q9UM47-1.2	A2138H	Neutral	0.259
NOTCH3	Q9UM47-1.2	A2138I	Neutral	0.07
NOTCH3	Q9UM47-1.2	A2138K	Neutral	0.068
NOTCH3	Q9UM47-1.2	A2138L	Neutral	0.07
NOTCH3	Q9UM47-1.2	A2138M	Neutral	0.07
NOTCH3	Q9UM47-1.2	A2138N	Neutral	0.277
NOTCH3	Q9UM47-1.2	A2138P	Neutral	0.079
NOTCH3	Q9UM47-1.2	A2138Q	Neutral	0.072
NOTCH3	Q9UM47-1.2	A2138R	Neutral	0.064
NOTCH3	Q9UM47-1.2	A2138S	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2138T	Neutral	0.018
NOTCH3	Q9UM47-1.2	A2138V	Neutral	0.018
NOTCH3	Q9UM47-1.2	A2138W	Pathogenic	0.575
NOTCH3	Q9UM47-1.2	A2138Y	Neutral	0.243
NOTCH3	Q9UM47-1.2	Q2139A	Neutral	0.018
NOTCH3	Q9UM47-1.2	Q2139C	Neutral	0.295
NOTCH3	Q9UM47-1.2	Q2139D	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q2139E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q2139F	Neutral	0.302
NOTCH3	Q9UM47-1.2	Q2139G	Neutral	0.073
NOTCH3	Q9UM47-1.2	Q2139H	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q2139I	Neutral	0.311
NOTCH3	Q9UM47-1.2	Q2139K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q2139L	Neutral	0.09
NOTCH3	Q9UM47-1.2	Q2139M	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q2139N	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q2139P	Neutral	0.02
NOTCH3	Q9UM47-1.2	Q2139R	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q2139S	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q2139T	Neutral	0.02
NOTCH3	Q9UM47-1.2	Q2139V	Neutral	0.09
NOTCH3	Q9UM47-1.2	Q2139W	Neutral	0.079
NOTCH3	Q9UM47-1.2	Q2139Y	Neutral	0.02
NOTCH3	Q9UM47-1.2	L2140A	Neutral	0.019
NOTCH3	Q9UM47-1.2	L2140C	Neutral	0.02
NOTCH3	Q9UM47-1.2	L2140D	Pathogenic	0.668
NOTCH3	Q9UM47-1.2	L2140E	Neutral	0.321
NOTCH3	Q9UM47-1.2	L2140F	Neutral	0.005
NOTCH3	Q9UM47-1.2	L2140G	Pathogenic	0.628
NOTCH3	Q9UM47-1.2	L2140H	Neutral	0.327
NOTCH3	Q9UM47-1.2	L2140I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2140K	Neutral	0.096
NOTCH3	Q9UM47-1.2	L2140M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2140N	Neutral	0.31
NOTCH3	Q9UM47-1.2	L2140P	Neutral	0.303
NOTCH3	Q9UM47-1.2	L2140Q	Neutral	0.095
NOTCH3	Q9UM47-1.2	L2140R	Neutral	0.091
NOTCH3	Q9UM47-1.2	L2140S	Neutral	0.082
NOTCH3	Q9UM47-1.2	L2140T	Neutral	0.021
NOTCH3	Q9UM47-1.2	L2140V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2140W	Neutral	0.085
NOTCH3	Q9UM47-1.2	L2140Y	Neutral	0.022
NOTCH3	Q9UM47-1.2	G2141A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2141C	Neutral	0.133
NOTCH3	Q9UM47-1.2	G2141D	Neutral	0.007
NOTCH3	Q9UM47-1.2	G2141E	Neutral	0.03
NOTCH3	Q9UM47-1.2	G2141F	Neutral	0.113
NOTCH3	Q9UM47-1.2	G2141H	Neutral	0.029
NOTCH3	Q9UM47-1.2	G2141I	Neutral	0.377
NOTCH3	Q9UM47-1.2	G2141K	Neutral	0.027
NOTCH3	Q9UM47-1.2	G2141L	Neutral	0.377
NOTCH3	Q9UM47-1.2	G2141M	Neutral	0.117
NOTCH3	Q9UM47-1.2	G2141N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2141P	Neutral	0.032
NOTCH3	Q9UM47-1.2	G2141Q	Neutral	0.029
NOTCH3	Q9UM47-1.2	G2141R	Neutral	0.026
NOTCH3	Q9UM47-1.2	G2141S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2141T	Neutral	0.031
NOTCH3	Q9UM47-1.2	G2141V	Neutral	0.125
NOTCH3	Q9UM47-1.2	G2141W	Neutral	0.025
NOTCH3	Q9UM47-1.2	G2141Y	Neutral	0.11
NOTCH3	Q9UM47-1.2	G2142A	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2142C	Neutral	0.233
NOTCH3	Q9UM47-1.2	G2142D	Neutral	0.014
NOTCH3	Q9UM47-1.2	G2142E	Neutral	0.058
NOTCH3	Q9UM47-1.2	G2142F	Neutral	0.202
NOTCH3	Q9UM47-1.2	G2142H	Neutral	0.055
NOTCH3	Q9UM47-1.2	G2142I	Pathogenic	0.547
NOTCH3	Q9UM47-1.2	G2142K	Neutral	0.052
NOTCH3	Q9UM47-1.2	G2142L	Pathogenic	0.546
NOTCH3	Q9UM47-1.2	G2142M	Neutral	0.209
NOTCH3	Q9UM47-1.2	G2142N	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2142P	Neutral	0.062
NOTCH3	Q9UM47-1.2	G2142Q	Neutral	0.056
NOTCH3	Q9UM47-1.2	G2142R	Neutral	0.05
NOTCH3	Q9UM47-1.2	G2142S	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2142T	Neutral	0.061
NOTCH3	Q9UM47-1.2	G2142V	Neutral	0.221
NOTCH3	Q9UM47-1.2	G2142W	Neutral	0.048
NOTCH3	Q9UM47-1.2	G2142Y	Neutral	0.198
NOTCH3	Q9UM47-1.2	P2143A	Neutral	0.063
NOTCH3	Q9UM47-1.2	P2143C	Pathogenic	0.599
NOTCH3	Q9UM47-1.2	P2143D	Neutral	0.068
NOTCH3	Q9UM47-1.2	P2143E	Neutral	0.064
NOTCH3	Q9UM47-1.2	P2143F	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	P2143G	Neutral	0.221
NOTCH3	Q9UM47-1.2	P2143H	Neutral	0.23
NOTCH3	Q9UM47-1.2	P2143I	Pathogenic	0.572
NOTCH3	Q9UM47-1.2	P2143K	Neutral	0.059
NOTCH3	Q9UM47-1.2	P2143L	Pathogenic	0.572
NOTCH3	Q9UM47-1.2	P2143M	Neutral	0.226
NOTCH3	Q9UM47-1.2	P2143N	Neutral	0.247
NOTCH3	Q9UM47-1.2	P2143Q	Neutral	0.063
NOTCH3	Q9UM47-1.2	P2143R	Neutral	0.212
NOTCH3	Q9UM47-1.2	P2143S	Neutral	0.064
NOTCH3	Q9UM47-1.2	P2143T	Neutral	0.067
NOTCH3	Q9UM47-1.2	P2143V	Neutral	0.239
NOTCH3	Q9UM47-1.2	P2143W	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	P2143Y	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	G2144A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2144C	Neutral	0.142
NOTCH3	Q9UM47-1.2	G2144D	Neutral	0.008
NOTCH3	Q9UM47-1.2	G2144E	Neutral	0.032
NOTCH3	Q9UM47-1.2	G2144F	Neutral	0.121
NOTCH3	Q9UM47-1.2	G2144H	Neutral	0.031
NOTCH3	Q9UM47-1.2	G2144I	Neutral	0.396
NOTCH3	Q9UM47-1.2	G2144K	Neutral	0.029
NOTCH3	Q9UM47-1.2	G2144L	Neutral	0.396
NOTCH3	Q9UM47-1.2	G2144M	Neutral	0.125
NOTCH3	Q9UM47-1.2	G2144N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2144P	Neutral	0.034
NOTCH3	Q9UM47-1.2	G2144Q	Neutral	0.031
NOTCH3	Q9UM47-1.2	G2144R	Neutral	0.028
NOTCH3	Q9UM47-1.2	G2144S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2144T	Neutral	0.034
NOTCH3	Q9UM47-1.2	G2144V	Neutral	0.134
NOTCH3	Q9UM47-1.2	G2144W	Neutral	0.027
NOTCH3	Q9UM47-1.2	G2144Y	Neutral	0.118
NOTCH3	Q9UM47-1.2	R2145A	Neutral	0.186
NOTCH3	Q9UM47-1.2	R2145C	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	R2145D	Pathogenic	0.531
NOTCH3	Q9UM47-1.2	R2145E	Neutral	0.055
NOTCH3	Q9UM47-1.2	R2145F	Pathogenic	0.862
NOTCH3	Q9UM47-1.2	R2145G	Neutral	0.491
NOTCH3	Q9UM47-1.2	R2145H	Neutral	0.057
NOTCH3	Q9UM47-1.2	R2145I	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	R2145K	Neutral	0.003
NOTCH3	Q9UM47-1.2	R2145L	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	R2145M	Neutral	0.223
NOTCH3	Q9UM47-1.2	R2145N	Neutral	0.053
NOTCH3	Q9UM47-1.2	R2145P	Pathogenic	0.533
NOTCH3	Q9UM47-1.2	R2145Q	Neutral	0.013
NOTCH3	Q9UM47-1.2	R2145S	Neutral	0.189
NOTCH3	Q9UM47-1.2	R2145T	Neutral	0.202
NOTCH3	Q9UM47-1.2	R2145V	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	R2145W	Pathogenic	0.861
NOTCH3	Q9UM47-1.2	R2145Y	Pathogenic	0.582
NOTCH3	Q9UM47-1.2	A2146C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2146D	Neutral	0.062
NOTCH3	Q9UM47-1.2	A2146E	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2146F	Neutral	0.053
NOTCH3	Q9UM47-1.2	A2146G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2146H	Neutral	0.056
NOTCH3	Q9UM47-1.2	A2146I	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2146K	Neutral	0.012
NOTCH3	Q9UM47-1.2	A2146L	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2146M	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2146N	Neutral	0.061
NOTCH3	Q9UM47-1.2	A2146P	Neutral	0.014
NOTCH3	Q9UM47-1.2	A2146Q	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2146R	Neutral	0.012
NOTCH3	Q9UM47-1.2	A2146S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2146T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2146V	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2146W	Neutral	0.187
NOTCH3	Q9UM47-1.2	A2146Y	Neutral	0.052
NOTCH3	Q9UM47-1.2	G2147A	Neutral	0.001
NOTCH3	Q9UM47-1.2	G2147C	Neutral	0.105
NOTCH3	Q9UM47-1.2	G2147D	Neutral	0.006
NOTCH3	Q9UM47-1.2	G2147E	Neutral	0.023
NOTCH3	Q9UM47-1.2	G2147F	Neutral	0.089
NOTCH3	Q9UM47-1.2	G2147H	Neutral	0.022
NOTCH3	Q9UM47-1.2	G2147I	Neutral	0.317
NOTCH3	Q9UM47-1.2	G2147K	Neutral	0.021
NOTCH3	Q9UM47-1.2	G2147L	Neutral	0.317
NOTCH3	Q9UM47-1.2	G2147M	Neutral	0.092
NOTCH3	Q9UM47-1.2	G2147N	Neutral	0.001
NOTCH3	Q9UM47-1.2	G2147P	Neutral	0.025
NOTCH3	Q9UM47-1.2	G2147Q	Neutral	0.022
NOTCH3	Q9UM47-1.2	G2147R	Neutral	0.02
NOTCH3	Q9UM47-1.2	G2147S	Neutral	0.001
NOTCH3	Q9UM47-1.2	G2147T	Neutral	0.024
NOTCH3	Q9UM47-1.2	G2147V	Neutral	0.098
NOTCH3	Q9UM47-1.2	G2147W	Neutral	0.019
NOTCH3	Q9UM47-1.2	G2147Y	Neutral	0.087
NOTCH3	Q9UM47-1.2	L2148A	Neutral	0.099
NOTCH3	Q9UM47-1.2	L2148C	Neutral	0.105
NOTCH3	Q9UM47-1.2	L2148D	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	L2148E	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	L2148F	Neutral	0.028
NOTCH3	Q9UM47-1.2	L2148G	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	L2148H	Pathogenic	0.736
NOTCH3	Q9UM47-1.2	L2148I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2148K	Neutral	0.377
NOTCH3	Q9UM47-1.2	L2148M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2148N	Pathogenic	0.72
NOTCH3	Q9UM47-1.2	L2148P	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	L2148Q	Neutral	0.376
NOTCH3	Q9UM47-1.2	L2148R	Neutral	0.365
NOTCH3	Q9UM47-1.2	L2148S	Neutral	0.34
NOTCH3	Q9UM47-1.2	L2148T	Neutral	0.109
NOTCH3	Q9UM47-1.2	L2148V	Neutral	0.006
NOTCH3	Q9UM47-1.2	L2148W	Neutral	0.348
NOTCH3	Q9UM47-1.2	L2148Y	Neutral	0.113
NOTCH3	Q9UM47-1.2	G2149A	Neutral	0.001
NOTCH3	Q9UM47-1.2	G2149C	Neutral	0.074
NOTCH3	Q9UM47-1.2	G2149D	Neutral	0.004
NOTCH3	Q9UM47-1.2	G2149E	Neutral	0.016
NOTCH3	Q9UM47-1.2	G2149F	Neutral	0.063
NOTCH3	Q9UM47-1.2	G2149H	Neutral	0.015
NOTCH3	Q9UM47-1.2	G2149I	Neutral	0.241
NOTCH3	Q9UM47-1.2	G2149K	Neutral	0.014
NOTCH3	Q9UM47-1.2	G2149L	Neutral	0.241
NOTCH3	Q9UM47-1.2	G2149M	Neutral	0.065
NOTCH3	Q9UM47-1.2	G2149N	Neutral	0.001
NOTCH3	Q9UM47-1.2	G2149P	Neutral	0.017
NOTCH3	Q9UM47-1.2	G2149Q	Neutral	0.015
NOTCH3	Q9UM47-1.2	G2149R	Neutral	0.014
NOTCH3	Q9UM47-1.2	G2149S	Neutral	0.001
NOTCH3	Q9UM47-1.2	G2149T	Neutral	0.017
NOTCH3	Q9UM47-1.2	G2149V	Neutral	0.07
NOTCH3	Q9UM47-1.2	G2149W	Neutral	0.013
NOTCH3	Q9UM47-1.2	G2149Y	Neutral	0.061
NOTCH3	Q9UM47-1.2	R2150A	Neutral	0.02
NOTCH3	Q9UM47-1.2	R2150C	Neutral	0.314
NOTCH3	Q9UM47-1.2	R2150D	Neutral	0.092
NOTCH3	Q9UM47-1.2	R2150E	Neutral	0.005
NOTCH3	Q9UM47-1.2	R2150F	Neutral	0.357
NOTCH3	Q9UM47-1.2	R2150G	Neutral	0.079
NOTCH3	Q9UM47-1.2	R2150H	Neutral	0.005
NOTCH3	Q9UM47-1.2	R2150I	Neutral	0.348
NOTCH3	Q9UM47-1.2	R2150K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R2150L	Neutral	0.105
NOTCH3	Q9UM47-1.2	R2150M	Neutral	0.025
NOTCH3	Q9UM47-1.2	R2150N	Neutral	0.005
NOTCH3	Q9UM47-1.2	R2150P	Neutral	0.092
NOTCH3	Q9UM47-1.2	R2150Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	R2150S	Neutral	0.02
NOTCH3	Q9UM47-1.2	R2150T	Neutral	0.022
NOTCH3	Q9UM47-1.2	R2150V	Neutral	0.33
NOTCH3	Q9UM47-1.2	R2150W	Neutral	0.356
NOTCH3	Q9UM47-1.2	R2150Y	Neutral	0.11
NOTCH3	Q9UM47-1.2	Q2151A	Neutral	0.019
NOTCH3	Q9UM47-1.2	Q2151C	Neutral	0.299
NOTCH3	Q9UM47-1.2	Q2151D	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q2151E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q2151F	Neutral	0.306
NOTCH3	Q9UM47-1.2	Q2151G	Neutral	0.074
NOTCH3	Q9UM47-1.2	Q2151H	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q2151I	Neutral	0.315
NOTCH3	Q9UM47-1.2	Q2151K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q2151L	Neutral	0.092
NOTCH3	Q9UM47-1.2	Q2151M	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q2151N	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q2151P	Neutral	0.02
NOTCH3	Q9UM47-1.2	Q2151R	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q2151S	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q2151T	Neutral	0.021
NOTCH3	Q9UM47-1.2	Q2151V	Neutral	0.092
NOTCH3	Q9UM47-1.2	Q2151W	Neutral	0.08
NOTCH3	Q9UM47-1.2	Q2151Y	Neutral	0.02
NOTCH3	Q9UM47-1.2	P2152A	Neutral	0.065
NOTCH3	Q9UM47-1.2	P2152C	Pathogenic	0.609
NOTCH3	Q9UM47-1.2	P2152D	Neutral	0.071
NOTCH3	Q9UM47-1.2	P2152E	Neutral	0.067
NOTCH3	Q9UM47-1.2	P2152F	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	P2152G	Neutral	0.229
NOTCH3	Q9UM47-1.2	P2152H	Neutral	0.238
NOTCH3	Q9UM47-1.2	P2152I	Pathogenic	0.583
NOTCH3	Q9UM47-1.2	P2152K	Neutral	0.061
NOTCH3	Q9UM47-1.2	P2152L	Pathogenic	0.583
NOTCH3	Q9UM47-1.2	P2152M	Neutral	0.234
NOTCH3	Q9UM47-1.2	P2152N	Neutral	0.255
NOTCH3	Q9UM47-1.2	P2152Q	Neutral	0.065
NOTCH3	Q9UM47-1.2	P2152R	Neutral	0.22
NOTCH3	Q9UM47-1.2	P2152S	Neutral	0.067
NOTCH3	Q9UM47-1.2	P2152T	Neutral	0.07
NOTCH3	Q9UM47-1.2	P2152V	Neutral	0.248
NOTCH3	Q9UM47-1.2	P2152W	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	P2152Y	Pathogenic	0.565
NOTCH3	Q9UM47-1.2	P2153A	Neutral	0.141
NOTCH3	Q9UM47-1.2	P2153C	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	P2153D	Neutral	0.153
NOTCH3	Q9UM47-1.2	P2153E	Neutral	0.144
NOTCH3	Q9UM47-1.2	P2153F	Pathogenic	0.935
NOTCH3	Q9UM47-1.2	P2153G	Neutral	0.411
NOTCH3	Q9UM47-1.2	P2153H	Neutral	0.424
NOTCH3	Q9UM47-1.2	P2153I	Pathogenic	0.767
NOTCH3	Q9UM47-1.2	P2153K	Neutral	0.133
NOTCH3	Q9UM47-1.2	P2153L	Pathogenic	0.767
NOTCH3	Q9UM47-1.2	P2153M	Neutral	0.418
NOTCH3	Q9UM47-1.2	P2153N	Neutral	0.446
NOTCH3	Q9UM47-1.2	P2153Q	Neutral	0.141
NOTCH3	Q9UM47-1.2	P2153R	Neutral	0.398
NOTCH3	Q9UM47-1.2	P2153S	Neutral	0.145
NOTCH3	Q9UM47-1.2	P2153T	Neutral	0.151
NOTCH3	Q9UM47-1.2	P2153V	Neutral	0.436
NOTCH3	Q9UM47-1.2	P2153W	Pathogenic	0.928
NOTCH3	Q9UM47-1.2	P2153Y	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	G2154A	Neutral	0.018
NOTCH3	Q9UM47-1.2	G2154C	Pathogenic	0.618
NOTCH3	Q9UM47-1.2	G2154D	Neutral	0.071
NOTCH3	Q9UM47-1.2	G2154E	Neutral	0.245
NOTCH3	Q9UM47-1.2	G2154F	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	G2154H	Neutral	0.238
NOTCH3	Q9UM47-1.2	G2154I	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	G2154K	Neutral	0.227
NOTCH3	Q9UM47-1.2	G2154L	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	G2154M	Pathogenic	0.583
NOTCH3	Q9UM47-1.2	G2154N	Neutral	0.016
NOTCH3	Q9UM47-1.2	G2154P	Neutral	0.259
NOTCH3	Q9UM47-1.2	G2154Q	Neutral	0.241
NOTCH3	Q9UM47-1.2	G2154R	Neutral	0.219
NOTCH3	Q9UM47-1.2	G2154S	Neutral	0.018
NOTCH3	Q9UM47-1.2	G2154T	Neutral	0.256
NOTCH3	Q9UM47-1.2	G2154V	Pathogenic	0.601
NOTCH3	Q9UM47-1.2	G2154W	Neutral	0.211
NOTCH3	Q9UM47-1.2	G2154Y	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	G2155A	Neutral	0.022
NOTCH3	Q9UM47-1.2	G2155C	Pathogenic	0.668
NOTCH3	Q9UM47-1.2	G2155D	Neutral	0.087
NOTCH3	Q9UM47-1.2	G2155E	Neutral	0.287
NOTCH3	Q9UM47-1.2	G2155F	Pathogenic	0.626
NOTCH3	Q9UM47-1.2	G2155H	Neutral	0.279
NOTCH3	Q9UM47-1.2	G2155I	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	G2155K	Neutral	0.268
NOTCH3	Q9UM47-1.2	G2155L	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	G2155M	Pathogenic	0.635
NOTCH3	Q9UM47-1.2	G2155N	Neutral	0.02
NOTCH3	Q9UM47-1.2	G2155P	Neutral	0.303
NOTCH3	Q9UM47-1.2	G2155Q	Neutral	0.283
NOTCH3	Q9UM47-1.2	G2155R	Neutral	0.258
NOTCH3	Q9UM47-1.2	G2155S	Neutral	0.022
NOTCH3	Q9UM47-1.2	G2155T	Neutral	0.299
NOTCH3	Q9UM47-1.2	G2155V	Pathogenic	0.652
NOTCH3	Q9UM47-1.2	G2155W	Neutral	0.249
NOTCH3	Q9UM47-1.2	G2155Y	Pathogenic	0.619
NOTCH3	Q9UM47-1.2	C2156A	Neutral	0.001
NOTCH3	Q9UM47-1.2	C2156D	Neutral	0.087
NOTCH3	Q9UM47-1.2	C2156E	Neutral	0.287
NOTCH3	Q9UM47-1.2	C2156F	Neutral	0.017
NOTCH3	Q9UM47-1.2	C2156G	Neutral	0.077
NOTCH3	Q9UM47-1.2	C2156H	Neutral	0.078
NOTCH3	Q9UM47-1.2	C2156I	Neutral	0.004
NOTCH3	Q9UM47-1.2	C2156K	Neutral	0.074
NOTCH3	Q9UM47-1.2	C2156L	Neutral	0.004
NOTCH3	Q9UM47-1.2	C2156M	Neutral	0.004
NOTCH3	Q9UM47-1.2	C2156N	Neutral	0.085
NOTCH3	Q9UM47-1.2	C2156P	Neutral	0.086
NOTCH3	Q9UM47-1.2	C2156Q	Neutral	0.08
NOTCH3	Q9UM47-1.2	C2156R	Neutral	0.071
NOTCH3	Q9UM47-1.2	C2156S	Neutral	0.004
NOTCH3	Q9UM47-1.2	C2156T	Neutral	0.004
NOTCH3	Q9UM47-1.2	C2156V	Neutral	0.004
NOTCH3	Q9UM47-1.2	C2156W	Neutral	0.015
NOTCH3	Q9UM47-1.2	C2156Y	Neutral	0.017
NOTCH3	Q9UM47-1.2	V2157A	Neutral	0.008
NOTCH3	Q9UM47-1.2	V2157C	Neutral	0.039
NOTCH3	Q9UM47-1.2	V2157D	Neutral	0.467
NOTCH3	Q9UM47-1.2	V2157E	Neutral	0.167
NOTCH3	Q9UM47-1.2	V2157F	Neutral	0.038
NOTCH3	Q9UM47-1.2	V2157G	Neutral	0.425
NOTCH3	Q9UM47-1.2	V2157H	Neutral	0.466
NOTCH3	Q9UM47-1.2	V2157I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V2157K	Neutral	0.154
NOTCH3	Q9UM47-1.2	V2157L	Neutral	0.002
NOTCH3	Q9UM47-1.2	V2157M	Neutral	0.002
NOTCH3	Q9UM47-1.2	V2157N	Neutral	0.472
NOTCH3	Q9UM47-1.2	V2157P	Neutral	0.159
NOTCH3	Q9UM47-1.2	V2157Q	Neutral	0.163
NOTCH3	Q9UM47-1.2	V2157R	Neutral	0.44
NOTCH3	Q9UM47-1.2	V2157S	Neutral	0.152
NOTCH3	Q9UM47-1.2	V2157T	Neutral	0.009
NOTCH3	Q9UM47-1.2	V2157W	Neutral	0.423
NOTCH3	Q9UM47-1.2	V2157Y	Neutral	0.037
NOTCH3	Q9UM47-1.2	L2158A	Neutral	0.024
NOTCH3	Q9UM47-1.2	L2158C	Neutral	0.025
NOTCH3	Q9UM47-1.2	L2158D	Pathogenic	0.717
NOTCH3	Q9UM47-1.2	L2158E	Neutral	0.373
NOTCH3	Q9UM47-1.2	L2158F	Neutral	0.006
NOTCH3	Q9UM47-1.2	L2158G	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	L2158H	Neutral	0.38
NOTCH3	Q9UM47-1.2	L2158I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2158K	Neutral	0.118
NOTCH3	Q9UM47-1.2	L2158M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2158N	Neutral	0.362
NOTCH3	Q9UM47-1.2	L2158P	Neutral	0.354
NOTCH3	Q9UM47-1.2	L2158Q	Neutral	0.117
NOTCH3	Q9UM47-1.2	L2158R	Neutral	0.113
NOTCH3	Q9UM47-1.2	L2158S	Neutral	0.102
NOTCH3	Q9UM47-1.2	L2158T	Neutral	0.026
NOTCH3	Q9UM47-1.2	L2158V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2158W	Neutral	0.105
NOTCH3	Q9UM47-1.2	L2158Y	Neutral	0.027
NOTCH3	Q9UM47-1.2	S2159A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2159C	Neutral	0.027
NOTCH3	Q9UM47-1.2	S2159D	Neutral	0.006
NOTCH3	Q9UM47-1.2	S2159E	Neutral	0.005
NOTCH3	Q9UM47-1.2	S2159F	Neutral	0.095
NOTCH3	Q9UM47-1.2	S2159G	Neutral	0.006
NOTCH3	Q9UM47-1.2	S2159H	Neutral	0.024
NOTCH3	Q9UM47-1.2	S2159I	Neutral	0.098
NOTCH3	Q9UM47-1.2	S2159K	Neutral	0.005
NOTCH3	Q9UM47-1.2	S2159L	Neutral	0.098
NOTCH3	Q9UM47-1.2	S2159M	Neutral	0.023
NOTCH3	Q9UM47-1.2	S2159N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2159P	Neutral	0.026
NOTCH3	Q9UM47-1.2	S2159Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	S2159R	Neutral	0.021
NOTCH3	Q9UM47-1.2	S2159T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2159V	Neutral	0.104
NOTCH3	Q9UM47-1.2	S2159W	Neutral	0.3
NOTCH3	Q9UM47-1.2	S2159Y	Neutral	0.092
NOTCH3	Q9UM47-1.2	L2160A	Neutral	0.023
NOTCH3	Q9UM47-1.2	L2160C	Neutral	0.024
NOTCH3	Q9UM47-1.2	L2160D	Pathogenic	0.707
NOTCH3	Q9UM47-1.2	L2160E	Neutral	0.362
NOTCH3	Q9UM47-1.2	L2160F	Neutral	0.006
NOTCH3	Q9UM47-1.2	L2160G	Pathogenic	0.67
NOTCH3	Q9UM47-1.2	L2160H	Neutral	0.369
NOTCH3	Q9UM47-1.2	L2160I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2160K	Neutral	0.113
NOTCH3	Q9UM47-1.2	L2160M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2160N	Neutral	0.35
NOTCH3	Q9UM47-1.2	L2160P	Neutral	0.343
NOTCH3	Q9UM47-1.2	L2160Q	Neutral	0.112
NOTCH3	Q9UM47-1.2	L2160R	Neutral	0.108
NOTCH3	Q9UM47-1.2	L2160S	Neutral	0.097
NOTCH3	Q9UM47-1.2	L2160T	Neutral	0.025
NOTCH3	Q9UM47-1.2	L2160V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2160W	Neutral	0.101
NOTCH3	Q9UM47-1.2	L2160Y	Neutral	0.026
NOTCH3	Q9UM47-1.2	G2161A	Neutral	0.051
NOTCH3	Q9UM47-1.2	G2161C	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	G2161D	Neutral	0.184
NOTCH3	Q9UM47-1.2	G2161E	Neutral	0.489
NOTCH3	Q9UM47-1.2	G2161F	Pathogenic	0.799
NOTCH3	Q9UM47-1.2	G2161H	Neutral	0.479
NOTCH3	Q9UM47-1.2	G2161I	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	G2161K	Neutral	0.465
NOTCH3	Q9UM47-1.2	G2161L	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	G2161M	Pathogenic	0.805
NOTCH3	Q9UM47-1.2	G2161N	Neutral	0.046
NOTCH3	Q9UM47-1.2	G2161P	Pathogenic	0.508
NOTCH3	Q9UM47-1.2	G2161Q	Neutral	0.483
NOTCH3	Q9UM47-1.2	G2161R	Neutral	0.452
NOTCH3	Q9UM47-1.2	G2161S	Neutral	0.05
NOTCH3	Q9UM47-1.2	G2161T	Pathogenic	0.504
NOTCH3	Q9UM47-1.2	G2161V	Pathogenic	0.816
NOTCH3	Q9UM47-1.2	G2161W	Neutral	0.441
NOTCH3	Q9UM47-1.2	G2161Y	Pathogenic	0.794
NOTCH3	Q9UM47-1.2	L2162A	Neutral	0.009
NOTCH3	Q9UM47-1.2	L2162C	Neutral	0.009
NOTCH3	Q9UM47-1.2	L2162D	Neutral	0.481
NOTCH3	Q9UM47-1.2	L2162E	Neutral	0.179
NOTCH3	Q9UM47-1.2	L2162F	Neutral	0.002
NOTCH3	Q9UM47-1.2	L2162G	Neutral	0.438
NOTCH3	Q9UM47-1.2	L2162H	Neutral	0.183
NOTCH3	Q9UM47-1.2	L2162I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2162K	Neutral	0.046
NOTCH3	Q9UM47-1.2	L2162M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2162N	Neutral	0.171
NOTCH3	Q9UM47-1.2	L2162P	Neutral	0.167
NOTCH3	Q9UM47-1.2	L2162Q	Neutral	0.046
NOTCH3	Q9UM47-1.2	L2162R	Neutral	0.044
NOTCH3	Q9UM47-1.2	L2162S	Neutral	0.04
NOTCH3	Q9UM47-1.2	L2162T	Neutral	0.01
NOTCH3	Q9UM47-1.2	L2162V	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2162W	Neutral	0.041
NOTCH3	Q9UM47-1.2	L2162Y	Neutral	0.01
NOTCH3	Q9UM47-1.2	L2163A	Neutral	0.048
NOTCH3	Q9UM47-1.2	L2163C	Neutral	0.051
NOTCH3	Q9UM47-1.2	L2163D	Pathogenic	0.839
NOTCH3	Q9UM47-1.2	L2163E	Pathogenic	0.551
NOTCH3	Q9UM47-1.2	L2163F	Neutral	0.013
NOTCH3	Q9UM47-1.2	L2163G	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	L2163H	Pathogenic	0.558
NOTCH3	Q9UM47-1.2	L2163I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2163K	Neutral	0.215
NOTCH3	Q9UM47-1.2	L2163M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2163N	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	L2163P	Pathogenic	0.53
NOTCH3	Q9UM47-1.2	L2163Q	Neutral	0.215
NOTCH3	Q9UM47-1.2	L2163R	Neutral	0.207
NOTCH3	Q9UM47-1.2	L2163S	Neutral	0.189
NOTCH3	Q9UM47-1.2	L2163T	Neutral	0.052
NOTCH3	Q9UM47-1.2	L2163V	Neutral	0.003
NOTCH3	Q9UM47-1.2	L2163W	Neutral	0.195
NOTCH3	Q9UM47-1.2	L2163Y	Neutral	0.055
NOTCH3	Q9UM47-1.2	N2164A	Neutral	0.056
NOTCH3	Q9UM47-1.2	N2164C	Neutral	0.225
NOTCH3	Q9UM47-1.2	N2164D	Neutral	0.001
NOTCH3	Q9UM47-1.2	N2164E	Neutral	0.003
NOTCH3	Q9UM47-1.2	N2164F	Neutral	0.207
NOTCH3	Q9UM47-1.2	N2164G	Neutral	0.003
NOTCH3	Q9UM47-1.2	N2164H	Neutral	0.001
NOTCH3	Q9UM47-1.2	N2164I	Neutral	0.214
NOTCH3	Q9UM47-1.2	N2164K	Neutral	0.003
NOTCH3	Q9UM47-1.2	N2164L	Neutral	0.214
NOTCH3	Q9UM47-1.2	N2164M	Neutral	0.056
NOTCH3	Q9UM47-1.2	N2164P	Neutral	0.061
NOTCH3	Q9UM47-1.2	N2164Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	N2164R	Neutral	0.003
NOTCH3	Q9UM47-1.2	N2164S	Neutral	0.001
NOTCH3	Q9UM47-1.2	N2164T	Neutral	0.003
NOTCH3	Q9UM47-1.2	N2164V	Neutral	0.226
NOTCH3	Q9UM47-1.2	N2164W	Pathogenic	0.517
NOTCH3	Q9UM47-1.2	N2164Y	Neutral	0.053
NOTCH3	Q9UM47-1.2	P2165A	Neutral	0.087
NOTCH3	Q9UM47-1.2	P2165C	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	P2165D	Neutral	0.095
NOTCH3	Q9UM47-1.2	P2165E	Neutral	0.089
NOTCH3	Q9UM47-1.2	P2165F	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	P2165G	Neutral	0.289
NOTCH3	Q9UM47-1.2	P2165H	Neutral	0.3
NOTCH3	Q9UM47-1.2	P2165I	Pathogenic	0.656
NOTCH3	Q9UM47-1.2	P2165K	Neutral	0.082
NOTCH3	Q9UM47-1.2	P2165L	Pathogenic	0.656
NOTCH3	Q9UM47-1.2	P2165M	Neutral	0.295
NOTCH3	Q9UM47-1.2	P2165N	Neutral	0.319
NOTCH3	Q9UM47-1.2	P2165Q	Neutral	0.087
NOTCH3	Q9UM47-1.2	P2165R	Neutral	0.278
NOTCH3	Q9UM47-1.2	P2165S	Neutral	0.089
NOTCH3	Q9UM47-1.2	P2165T	Neutral	0.094
NOTCH3	Q9UM47-1.2	P2165V	Neutral	0.31
NOTCH3	Q9UM47-1.2	P2165W	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	P2165Y	Pathogenic	0.64
NOTCH3	Q9UM47-1.2	V2166A	Neutral	0.022
NOTCH3	Q9UM47-1.2	V2166C	Neutral	0.101
NOTCH3	Q9UM47-1.2	V2166D	Pathogenic	0.706
NOTCH3	Q9UM47-1.2	V2166E	Neutral	0.353
NOTCH3	Q9UM47-1.2	V2166F	Neutral	0.097
NOTCH3	Q9UM47-1.2	V2166G	Pathogenic	0.669
NOTCH3	Q9UM47-1.2	V2166H	Pathogenic	0.705
NOTCH3	Q9UM47-1.2	V2166I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V2166K	Neutral	0.332
NOTCH3	Q9UM47-1.2	V2166L	Neutral	0.005
NOTCH3	Q9UM47-1.2	V2166M	Neutral	0.005
NOTCH3	Q9UM47-1.2	V2166N	Pathogenic	0.709
NOTCH3	Q9UM47-1.2	V2166P	Neutral	0.341
NOTCH3	Q9UM47-1.2	V2166Q	Neutral	0.348
NOTCH3	Q9UM47-1.2	V2166R	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	V2166S	Neutral	0.328
NOTCH3	Q9UM47-1.2	V2166T	Neutral	0.025
NOTCH3	Q9UM47-1.2	V2166W	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	V2166Y	Neutral	0.095
NOTCH3	Q9UM47-1.2	A2167C	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2167D	Neutral	0.085
NOTCH3	Q9UM47-1.2	A2167E	Neutral	0.019
NOTCH3	Q9UM47-1.2	A2167F	Neutral	0.073
NOTCH3	Q9UM47-1.2	A2167G	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2167H	Neutral	0.077
NOTCH3	Q9UM47-1.2	A2167I	Neutral	0.018
NOTCH3	Q9UM47-1.2	A2167K	Neutral	0.017
NOTCH3	Q9UM47-1.2	A2167L	Neutral	0.018
NOTCH3	Q9UM47-1.2	A2167M	Neutral	0.018
NOTCH3	Q9UM47-1.2	A2167N	Neutral	0.084
NOTCH3	Q9UM47-1.2	A2167P	Neutral	0.02
NOTCH3	Q9UM47-1.2	A2167Q	Neutral	0.018
NOTCH3	Q9UM47-1.2	A2167R	Neutral	0.016
NOTCH3	Q9UM47-1.2	A2167S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2167T	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2167V	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2167W	Neutral	0.245
NOTCH3	Q9UM47-1.2	A2167Y	Neutral	0.071
NOTCH3	Q9UM47-1.2	V2168A	Neutral	0.017
NOTCH3	Q9UM47-1.2	V2168C	Neutral	0.076
NOTCH3	Q9UM47-1.2	V2168D	Pathogenic	0.638
NOTCH3	Q9UM47-1.2	V2168E	Neutral	0.287
NOTCH3	Q9UM47-1.2	V2168F	Neutral	0.073
NOTCH3	Q9UM47-1.2	V2168G	Pathogenic	0.598
NOTCH3	Q9UM47-1.2	V2168H	Pathogenic	0.638
NOTCH3	Q9UM47-1.2	V2168I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V2168K	Neutral	0.268
NOTCH3	Q9UM47-1.2	V2168L	Neutral	0.004
NOTCH3	Q9UM47-1.2	V2168M	Neutral	0.004
NOTCH3	Q9UM47-1.2	V2168N	Pathogenic	0.643
NOTCH3	Q9UM47-1.2	V2168P	Neutral	0.276
NOTCH3	Q9UM47-1.2	V2168Q	Neutral	0.282
NOTCH3	Q9UM47-1.2	V2168R	Pathogenic	0.613
NOTCH3	Q9UM47-1.2	V2168S	Neutral	0.265
NOTCH3	Q9UM47-1.2	V2168T	Neutral	0.018
NOTCH3	Q9UM47-1.2	V2168W	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	V2168Y	Neutral	0.072
NOTCH3	Q9UM47-1.2	P2169A	Neutral	0.082
NOTCH3	Q9UM47-1.2	P2169C	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	P2169D	Neutral	0.09
NOTCH3	Q9UM47-1.2	P2169E	Neutral	0.084
NOTCH3	Q9UM47-1.2	P2169F	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	P2169G	Neutral	0.276
NOTCH3	Q9UM47-1.2	P2169H	Neutral	0.286
NOTCH3	Q9UM47-1.2	P2169I	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	P2169K	Neutral	0.077
NOTCH3	Q9UM47-1.2	P2169L	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	P2169M	Neutral	0.281
NOTCH3	Q9UM47-1.2	P2169N	Neutral	0.305
NOTCH3	Q9UM47-1.2	P2169Q	Neutral	0.082
NOTCH3	Q9UM47-1.2	P2169R	Neutral	0.265
NOTCH3	Q9UM47-1.2	P2169S	Neutral	0.084
NOTCH3	Q9UM47-1.2	P2169T	Neutral	0.088
NOTCH3	Q9UM47-1.2	P2169V	Neutral	0.296
NOTCH3	Q9UM47-1.2	P2169W	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	P2169Y	Pathogenic	0.625
NOTCH3	Q9UM47-1.2	L2170A	Neutral	0.006
NOTCH3	Q9UM47-1.2	L2170C	Neutral	0.006
NOTCH3	Q9UM47-1.2	L2170D	Neutral	0.378
NOTCH3	Q9UM47-1.2	L2170E	Neutral	0.125
NOTCH3	Q9UM47-1.2	L2170F	Neutral	0.002
NOTCH3	Q9UM47-1.2	L2170G	Neutral	0.339
NOTCH3	Q9UM47-1.2	L2170H	Neutral	0.128
NOTCH3	Q9UM47-1.2	L2170I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2170K	Neutral	0.031
NOTCH3	Q9UM47-1.2	L2170M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2170N	Neutral	0.12
NOTCH3	Q9UM47-1.2	L2170P	Neutral	0.116
NOTCH3	Q9UM47-1.2	L2170Q	Neutral	0.031
NOTCH3	Q9UM47-1.2	L2170R	Neutral	0.03
NOTCH3	Q9UM47-1.2	L2170S	Neutral	0.026
NOTCH3	Q9UM47-1.2	L2170T	Neutral	0.006
NOTCH3	Q9UM47-1.2	L2170V	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2170W	Neutral	0.027
NOTCH3	Q9UM47-1.2	L2170Y	Neutral	0.007
NOTCH3	Q9UM47-1.2	D2171A	Pathogenic	0.519
NOTCH3	Q9UM47-1.2	D2171C	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	D2171E	Neutral	0.003
NOTCH3	Q9UM47-1.2	D2171F	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	D2171G	Neutral	0.18
NOTCH3	Q9UM47-1.2	D2171H	Neutral	0.19
NOTCH3	Q9UM47-1.2	D2171I	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	D2171K	Neutral	0.179
NOTCH3	Q9UM47-1.2	D2171L	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	D2171M	Pathogenic	0.827
NOTCH3	Q9UM47-1.2	D2171N	Neutral	0.012
NOTCH3	Q9UM47-1.2	D2171P	Neutral	0.206
NOTCH3	Q9UM47-1.2	D2171Q	Neutral	0.049
NOTCH3	Q9UM47-1.2	D2171R	Neutral	0.485
NOTCH3	Q9UM47-1.2	D2171S	Neutral	0.05
NOTCH3	Q9UM47-1.2	D2171T	Neutral	0.205
NOTCH3	Q9UM47-1.2	D2171V	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	D2171W	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	D2171Y	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	W2172A	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W2172C	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	W2172D	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W2172E	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W2172F	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	W2172G	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	W2172H	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	W2172I	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W2172K	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W2172L	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	W2172M	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	W2172N	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W2172P	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W2172Q	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	W2172R	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W2172S	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W2172T	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	W2172V	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W2172Y	Neutral	0.291
NOTCH3	Q9UM47-1.2	A2173C	Neutral	0.002
NOTCH3	Q9UM47-1.2	A2173D	Neutral	0.034
NOTCH3	Q9UM47-1.2	A2173E	Neutral	0.007
NOTCH3	Q9UM47-1.2	A2173F	Neutral	0.029
NOTCH3	Q9UM47-1.2	A2173G	Neutral	0.002
NOTCH3	Q9UM47-1.2	A2173H	Neutral	0.03
NOTCH3	Q9UM47-1.2	A2173I	Neutral	0.007
NOTCH3	Q9UM47-1.2	A2173K	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2173L	Neutral	0.007
NOTCH3	Q9UM47-1.2	A2173M	Neutral	0.007
NOTCH3	Q9UM47-1.2	A2173N	Neutral	0.033
NOTCH3	Q9UM47-1.2	A2173P	Neutral	0.008
NOTCH3	Q9UM47-1.2	A2173Q	Neutral	0.007
NOTCH3	Q9UM47-1.2	A2173R	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2173S	Neutral	0.0
NOTCH3	Q9UM47-1.2	A2173T	Neutral	0.002
NOTCH3	Q9UM47-1.2	A2173V	Neutral	0.002
NOTCH3	Q9UM47-1.2	A2173W	Neutral	0.109
NOTCH3	Q9UM47-1.2	A2173Y	Neutral	0.028
NOTCH3	Q9UM47-1.2	R2174A	Neutral	0.487
NOTCH3	Q9UM47-1.2	R2174C	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	R2174D	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	R2174E	Neutral	0.196
NOTCH3	Q9UM47-1.2	R2174F	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	R2174G	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	R2174H	Neutral	0.202
NOTCH3	Q9UM47-1.2	R2174I	Pathogenic	0.961
NOTCH3	Q9UM47-1.2	R2174K	Neutral	0.013
NOTCH3	Q9UM47-1.2	R2174L	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	R2174M	Pathogenic	0.544
NOTCH3	Q9UM47-1.2	R2174N	Neutral	0.188
NOTCH3	Q9UM47-1.2	R2174P	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	R2174Q	Neutral	0.052
NOTCH3	Q9UM47-1.2	R2174S	Neutral	0.492
NOTCH3	Q9UM47-1.2	R2174T	Pathogenic	0.512
NOTCH3	Q9UM47-1.2	R2174V	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	R2174W	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	R2174Y	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	L2175A	Neutral	0.069
NOTCH3	Q9UM47-1.2	L2175C	Neutral	0.074
NOTCH3	Q9UM47-1.2	L2175D	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	L2175E	Pathogenic	0.647
NOTCH3	Q9UM47-1.2	L2175F	Neutral	0.019
NOTCH3	Q9UM47-1.2	L2175G	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	L2175H	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	L2175I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2175K	Neutral	0.291
NOTCH3	Q9UM47-1.2	L2175M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2175N	Pathogenic	0.635
NOTCH3	Q9UM47-1.2	L2175P	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	L2175Q	Neutral	0.29
NOTCH3	Q9UM47-1.2	L2175R	Neutral	0.28
NOTCH3	Q9UM47-1.2	L2175S	Neutral	0.258
NOTCH3	Q9UM47-1.2	L2175T	Neutral	0.076
NOTCH3	Q9UM47-1.2	L2175V	Neutral	0.004
NOTCH3	Q9UM47-1.2	L2175W	Neutral	0.265
NOTCH3	Q9UM47-1.2	L2175Y	Neutral	0.08
NOTCH3	Q9UM47-1.2	P2176A	Neutral	0.054
NOTCH3	Q9UM47-1.2	P2176C	Pathogenic	0.561
NOTCH3	Q9UM47-1.2	P2176D	Neutral	0.059
NOTCH3	Q9UM47-1.2	P2176E	Neutral	0.056
NOTCH3	Q9UM47-1.2	P2176F	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	P2176G	Neutral	0.196
NOTCH3	Q9UM47-1.2	P2176H	Neutral	0.205
NOTCH3	Q9UM47-1.2	P2176I	Pathogenic	0.535
NOTCH3	Q9UM47-1.2	P2176K	Neutral	0.051
NOTCH3	Q9UM47-1.2	P2176L	Pathogenic	0.534
NOTCH3	Q9UM47-1.2	P2176M	Neutral	0.201
NOTCH3	Q9UM47-1.2	P2176N	Neutral	0.22
NOTCH3	Q9UM47-1.2	P2176Q	Neutral	0.054
NOTCH3	Q9UM47-1.2	P2176R	Neutral	0.188
NOTCH3	Q9UM47-1.2	P2176S	Neutral	0.056
NOTCH3	Q9UM47-1.2	P2176T	Neutral	0.058
NOTCH3	Q9UM47-1.2	P2176V	Neutral	0.213
NOTCH3	Q9UM47-1.2	P2176W	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	P2176Y	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	P2177A	Neutral	0.083
NOTCH3	Q9UM47-1.2	P2177C	Pathogenic	0.669
NOTCH3	Q9UM47-1.2	P2177D	Neutral	0.091
NOTCH3	Q9UM47-1.2	P2177E	Neutral	0.085
NOTCH3	Q9UM47-1.2	P2177F	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	P2177G	Neutral	0.278
NOTCH3	Q9UM47-1.2	P2177H	Neutral	0.289
NOTCH3	Q9UM47-1.2	P2177I	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	P2177K	Neutral	0.078
NOTCH3	Q9UM47-1.2	P2177L	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	P2177M	Neutral	0.284
NOTCH3	Q9UM47-1.2	P2177N	Neutral	0.308
NOTCH3	Q9UM47-1.2	P2177Q	Neutral	0.083
NOTCH3	Q9UM47-1.2	P2177R	Neutral	0.268
NOTCH3	Q9UM47-1.2	P2177S	Neutral	0.085
NOTCH3	Q9UM47-1.2	P2177T	Neutral	0.089
NOTCH3	Q9UM47-1.2	P2177V	Neutral	0.299
NOTCH3	Q9UM47-1.2	P2177W	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	P2177Y	Pathogenic	0.628
NOTCH3	Q9UM47-1.2	P2178A	Neutral	0.017
NOTCH3	Q9UM47-1.2	P2178C	Neutral	0.276
NOTCH3	Q9UM47-1.2	P2178D	Neutral	0.018
NOTCH3	Q9UM47-1.2	P2178E	Neutral	0.017
NOTCH3	Q9UM47-1.2	P2178F	Pathogenic	0.599
NOTCH3	Q9UM47-1.2	P2178G	Neutral	0.068
NOTCH3	Q9UM47-1.2	P2178H	Neutral	0.071
NOTCH3	Q9UM47-1.2	P2178I	Neutral	0.255
NOTCH3	Q9UM47-1.2	P2178K	Neutral	0.016
NOTCH3	Q9UM47-1.2	P2178L	Neutral	0.255
NOTCH3	Q9UM47-1.2	P2178M	Neutral	0.07
NOTCH3	Q9UM47-1.2	P2178N	Neutral	0.077
NOTCH3	Q9UM47-1.2	P2178Q	Neutral	0.017
NOTCH3	Q9UM47-1.2	P2178R	Neutral	0.064
NOTCH3	Q9UM47-1.2	P2178S	Neutral	0.017
NOTCH3	Q9UM47-1.2	P2178T	Neutral	0.018
NOTCH3	Q9UM47-1.2	P2178V	Neutral	0.074
NOTCH3	Q9UM47-1.2	P2178W	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	P2178Y	Neutral	0.241
NOTCH3	Q9UM47-1.2	A2179C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2179D	Neutral	0.058
NOTCH3	Q9UM47-1.2	A2179E	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2179F	Neutral	0.05
NOTCH3	Q9UM47-1.2	A2179G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2179H	Neutral	0.053
NOTCH3	Q9UM47-1.2	A2179I	Neutral	0.012
NOTCH3	Q9UM47-1.2	A2179K	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2179L	Neutral	0.012
NOTCH3	Q9UM47-1.2	A2179M	Neutral	0.012
NOTCH3	Q9UM47-1.2	A2179N	Neutral	0.057
NOTCH3	Q9UM47-1.2	A2179P	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2179Q	Neutral	0.012
NOTCH3	Q9UM47-1.2	A2179R	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2179S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2179T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2179V	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2179W	Neutral	0.177
NOTCH3	Q9UM47-1.2	A2179Y	Neutral	0.049
NOTCH3	Q9UM47-1.2	P2180A	Neutral	0.008
NOTCH3	Q9UM47-1.2	P2180C	Neutral	0.15
NOTCH3	Q9UM47-1.2	P2180D	Neutral	0.009
NOTCH3	Q9UM47-1.2	P2180E	Neutral	0.008
NOTCH3	Q9UM47-1.2	P2180F	Neutral	0.408
NOTCH3	Q9UM47-1.2	P2180G	Neutral	0.032
NOTCH3	Q9UM47-1.2	P2180H	Neutral	0.034
NOTCH3	Q9UM47-1.2	P2180I	Neutral	0.136
NOTCH3	Q9UM47-1.2	P2180K	Neutral	0.007
NOTCH3	Q9UM47-1.2	P2180L	Neutral	0.136
NOTCH3	Q9UM47-1.2	P2180M	Neutral	0.033
NOTCH3	Q9UM47-1.2	P2180N	Neutral	0.037
NOTCH3	Q9UM47-1.2	P2180Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	P2180R	Neutral	0.031
NOTCH3	Q9UM47-1.2	P2180S	Neutral	0.008
NOTCH3	Q9UM47-1.2	P2180T	Neutral	0.008
NOTCH3	Q9UM47-1.2	P2180V	Neutral	0.036
NOTCH3	Q9UM47-1.2	P2180W	Neutral	0.383
NOTCH3	Q9UM47-1.2	P2180Y	Neutral	0.128
NOTCH3	Q9UM47-1.2	P2181A	Neutral	0.014
NOTCH3	Q9UM47-1.2	P2181C	Neutral	0.234
NOTCH3	Q9UM47-1.2	P2181D	Neutral	0.015
NOTCH3	Q9UM47-1.2	P2181E	Neutral	0.014
NOTCH3	Q9UM47-1.2	P2181F	Pathogenic	0.545
NOTCH3	Q9UM47-1.2	P2181G	Neutral	0.055
NOTCH3	Q9UM47-1.2	P2181H	Neutral	0.058
NOTCH3	Q9UM47-1.2	P2181I	Neutral	0.215
NOTCH3	Q9UM47-1.2	P2181K	Neutral	0.013
NOTCH3	Q9UM47-1.2	P2181L	Neutral	0.215
NOTCH3	Q9UM47-1.2	P2181M	Neutral	0.057
NOTCH3	Q9UM47-1.2	P2181N	Neutral	0.063
NOTCH3	Q9UM47-1.2	P2181Q	Neutral	0.014
NOTCH3	Q9UM47-1.2	P2181R	Neutral	0.052
NOTCH3	Q9UM47-1.2	P2181S	Neutral	0.014
NOTCH3	Q9UM47-1.2	P2181T	Neutral	0.015
NOTCH3	Q9UM47-1.2	P2181V	Neutral	0.061
NOTCH3	Q9UM47-1.2	P2181W	Pathogenic	0.519
NOTCH3	Q9UM47-1.2	P2181Y	Neutral	0.203
NOTCH3	Q9UM47-1.2	G2182A	Neutral	0.001
NOTCH3	Q9UM47-1.2	G2182C	Neutral	0.097
NOTCH3	Q9UM47-1.2	G2182D	Neutral	0.005
NOTCH3	Q9UM47-1.2	G2182E	Neutral	0.021
NOTCH3	Q9UM47-1.2	G2182F	Neutral	0.083
NOTCH3	Q9UM47-1.2	G2182H	Neutral	0.02
NOTCH3	Q9UM47-1.2	G2182I	Neutral	0.299
NOTCH3	Q9UM47-1.2	G2182K	Neutral	0.019
NOTCH3	Q9UM47-1.2	G2182L	Neutral	0.299
NOTCH3	Q9UM47-1.2	G2182M	Neutral	0.085
NOTCH3	Q9UM47-1.2	G2182N	Neutral	0.001
NOTCH3	Q9UM47-1.2	G2182P	Neutral	0.023
NOTCH3	Q9UM47-1.2	G2182Q	Neutral	0.021
NOTCH3	Q9UM47-1.2	G2182R	Neutral	0.018
NOTCH3	Q9UM47-1.2	G2182S	Neutral	0.001
NOTCH3	Q9UM47-1.2	G2182T	Neutral	0.022
NOTCH3	Q9UM47-1.2	G2182V	Neutral	0.091
NOTCH3	Q9UM47-1.2	G2182W	Neutral	0.017
NOTCH3	Q9UM47-1.2	G2182Y	Neutral	0.08
NOTCH3	Q9UM47-1.2	P2183A	Neutral	0.087
NOTCH3	Q9UM47-1.2	P2183C	Pathogenic	0.681
NOTCH3	Q9UM47-1.2	P2183D	Neutral	0.095
NOTCH3	Q9UM47-1.2	P2183E	Neutral	0.089
NOTCH3	Q9UM47-1.2	P2183F	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	P2183G	Neutral	0.289
NOTCH3	Q9UM47-1.2	P2183H	Neutral	0.3
NOTCH3	Q9UM47-1.2	P2183I	Pathogenic	0.657
NOTCH3	Q9UM47-1.2	P2183K	Neutral	0.082
NOTCH3	Q9UM47-1.2	P2183L	Pathogenic	0.656
NOTCH3	Q9UM47-1.2	P2183M	Neutral	0.295
NOTCH3	Q9UM47-1.2	P2183N	Neutral	0.319
NOTCH3	Q9UM47-1.2	P2183Q	Neutral	0.087
NOTCH3	Q9UM47-1.2	P2183R	Neutral	0.278
NOTCH3	Q9UM47-1.2	P2183S	Neutral	0.089
NOTCH3	Q9UM47-1.2	P2183T	Neutral	0.094
NOTCH3	Q9UM47-1.2	P2183V	Neutral	0.31
NOTCH3	Q9UM47-1.2	P2183W	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	P2183Y	Pathogenic	0.64
NOTCH3	Q9UM47-1.2	S2184A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2184C	Neutral	0.021
NOTCH3	Q9UM47-1.2	S2184D	Neutral	0.005
NOTCH3	Q9UM47-1.2	S2184E	Neutral	0.004
NOTCH3	Q9UM47-1.2	S2184F	Neutral	0.076
NOTCH3	Q9UM47-1.2	S2184G	Neutral	0.004
NOTCH3	Q9UM47-1.2	S2184H	Neutral	0.019
NOTCH3	Q9UM47-1.2	S2184I	Neutral	0.079
NOTCH3	Q9UM47-1.2	S2184K	Neutral	0.004
NOTCH3	Q9UM47-1.2	S2184L	Neutral	0.079
NOTCH3	Q9UM47-1.2	S2184M	Neutral	0.018
NOTCH3	Q9UM47-1.2	S2184N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2184P	Neutral	0.021
NOTCH3	Q9UM47-1.2	S2184Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	S2184R	Neutral	0.017
NOTCH3	Q9UM47-1.2	S2184T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2184V	Neutral	0.084
NOTCH3	Q9UM47-1.2	S2184W	Neutral	0.252
NOTCH3	Q9UM47-1.2	S2184Y	Neutral	0.074
NOTCH3	Q9UM47-1.2	F2185A	Neutral	0.189
NOTCH3	Q9UM47-1.2	F2185C	Neutral	0.199
NOTCH3	Q9UM47-1.2	F2185D	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	F2185E	Pathogenic	0.557
NOTCH3	Q9UM47-1.2	F2185G	Neutral	0.497
NOTCH3	Q9UM47-1.2	F2185H	Neutral	0.059
NOTCH3	Q9UM47-1.2	F2185I	Neutral	0.014
NOTCH3	Q9UM47-1.2	F2185K	Pathogenic	0.582
NOTCH3	Q9UM47-1.2	F2185L	Neutral	0.014
NOTCH3	Q9UM47-1.2	F2185M	Neutral	0.014
NOTCH3	Q9UM47-1.2	F2185N	Pathogenic	0.544
NOTCH3	Q9UM47-1.2	F2185P	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	F2185Q	Pathogenic	0.561
NOTCH3	Q9UM47-1.2	F2185R	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	F2185S	Neutral	0.193
NOTCH3	Q9UM47-1.2	F2185T	Neutral	0.205
NOTCH3	Q9UM47-1.2	F2185V	Neutral	0.056
NOTCH3	Q9UM47-1.2	F2185W	Neutral	0.003
NOTCH3	Q9UM47-1.2	F2185Y	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2186A	Neutral	0.01
NOTCH3	Q9UM47-1.2	L2186C	Neutral	0.011
NOTCH3	Q9UM47-1.2	L2186D	Pathogenic	0.512
NOTCH3	Q9UM47-1.2	L2186E	Neutral	0.198
NOTCH3	Q9UM47-1.2	L2186F	Neutral	0.003
NOTCH3	Q9UM47-1.2	L2186G	Neutral	0.469
NOTCH3	Q9UM47-1.2	L2186H	Neutral	0.203
NOTCH3	Q9UM47-1.2	L2186I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2186K	Neutral	0.052
NOTCH3	Q9UM47-1.2	L2186M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2186N	Neutral	0.19
NOTCH3	Q9UM47-1.2	L2186P	Neutral	0.185
NOTCH3	Q9UM47-1.2	L2186Q	Neutral	0.052
NOTCH3	Q9UM47-1.2	L2186R	Neutral	0.05
NOTCH3	Q9UM47-1.2	L2186S	Neutral	0.045
NOTCH3	Q9UM47-1.2	L2186T	Neutral	0.011
NOTCH3	Q9UM47-1.2	L2186V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2186W	Neutral	0.046
NOTCH3	Q9UM47-1.2	L2186Y	Neutral	0.012
NOTCH3	Q9UM47-1.2	L2187A	Neutral	0.052
NOTCH3	Q9UM47-1.2	L2187C	Neutral	0.055
NOTCH3	Q9UM47-1.2	L2187D	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	L2187E	Pathogenic	0.573
NOTCH3	Q9UM47-1.2	L2187F	Neutral	0.014
NOTCH3	Q9UM47-1.2	L2187G	Pathogenic	0.828
NOTCH3	Q9UM47-1.2	L2187H	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	L2187I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2187K	Neutral	0.231
NOTCH3	Q9UM47-1.2	L2187M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2187N	Pathogenic	0.561
NOTCH3	Q9UM47-1.2	L2187P	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	L2187Q	Neutral	0.231
NOTCH3	Q9UM47-1.2	L2187R	Neutral	0.222
NOTCH3	Q9UM47-1.2	L2187S	Neutral	0.204
NOTCH3	Q9UM47-1.2	L2187T	Neutral	0.057
NOTCH3	Q9UM47-1.2	L2187V	Neutral	0.003
NOTCH3	Q9UM47-1.2	L2187W	Neutral	0.21
NOTCH3	Q9UM47-1.2	L2187Y	Neutral	0.06
NOTCH3	Q9UM47-1.2	P2188A	Neutral	0.091
NOTCH3	Q9UM47-1.2	P2188C	Pathogenic	0.69
NOTCH3	Q9UM47-1.2	P2188D	Neutral	0.099
NOTCH3	Q9UM47-1.2	P2188E	Neutral	0.093
NOTCH3	Q9UM47-1.2	P2188F	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	P2188G	Neutral	0.297
NOTCH3	Q9UM47-1.2	P2188H	Neutral	0.309
NOTCH3	Q9UM47-1.2	P2188I	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	P2188K	Neutral	0.085
NOTCH3	Q9UM47-1.2	P2188L	Pathogenic	0.666
NOTCH3	Q9UM47-1.2	P2188M	Neutral	0.304
NOTCH3	Q9UM47-1.2	P2188N	Neutral	0.328
NOTCH3	Q9UM47-1.2	P2188Q	Neutral	0.091
NOTCH3	Q9UM47-1.2	P2188R	Neutral	0.286
NOTCH3	Q9UM47-1.2	P2188S	Neutral	0.093
NOTCH3	Q9UM47-1.2	P2188T	Neutral	0.097
NOTCH3	Q9UM47-1.2	P2188V	Neutral	0.319
NOTCH3	Q9UM47-1.2	P2188W	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	P2188Y	Pathogenic	0.65
NOTCH3	Q9UM47-1.2	L2189A	Neutral	0.007
NOTCH3	Q9UM47-1.2	L2189C	Neutral	0.007
NOTCH3	Q9UM47-1.2	L2189D	Neutral	0.417
NOTCH3	Q9UM47-1.2	L2189E	Neutral	0.144
NOTCH3	Q9UM47-1.2	L2189F	Neutral	0.002
NOTCH3	Q9UM47-1.2	L2189G	Neutral	0.376
NOTCH3	Q9UM47-1.2	L2189H	Neutral	0.147
NOTCH3	Q9UM47-1.2	L2189I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2189K	Neutral	0.036
NOTCH3	Q9UM47-1.2	L2189M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2189N	Neutral	0.138
NOTCH3	Q9UM47-1.2	L2189P	Neutral	0.134
NOTCH3	Q9UM47-1.2	L2189Q	Neutral	0.036
NOTCH3	Q9UM47-1.2	L2189R	Neutral	0.035
NOTCH3	Q9UM47-1.2	L2189S	Neutral	0.031
NOTCH3	Q9UM47-1.2	L2189T	Neutral	0.008
NOTCH3	Q9UM47-1.2	L2189V	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2189W	Neutral	0.032
NOTCH3	Q9UM47-1.2	L2189Y	Neutral	0.008
NOTCH3	Q9UM47-1.2	A2190C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2190D	Neutral	0.065
NOTCH3	Q9UM47-1.2	A2190E	Neutral	0.014
NOTCH3	Q9UM47-1.2	A2190F	Neutral	0.055
NOTCH3	Q9UM47-1.2	A2190G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2190H	Neutral	0.058
NOTCH3	Q9UM47-1.2	A2190I	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2190K	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2190L	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2190M	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2190N	Neutral	0.063
NOTCH3	Q9UM47-1.2	A2190P	Neutral	0.015
NOTCH3	Q9UM47-1.2	A2190Q	Neutral	0.014
NOTCH3	Q9UM47-1.2	A2190R	Neutral	0.012
NOTCH3	Q9UM47-1.2	A2190S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2190T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2190V	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2190W	Neutral	0.194
NOTCH3	Q9UM47-1.2	A2190Y	Neutral	0.054
NOTCH3	Q9UM47-1.2	P2191A	Neutral	0.034
NOTCH3	Q9UM47-1.2	P2191C	Neutral	0.44
NOTCH3	Q9UM47-1.2	P2191D	Neutral	0.037
NOTCH3	Q9UM47-1.2	P2191E	Neutral	0.035
NOTCH3	Q9UM47-1.2	P2191F	Pathogenic	0.754
NOTCH3	Q9UM47-1.2	P2191G	Neutral	0.13
NOTCH3	Q9UM47-1.2	P2191H	Neutral	0.136
NOTCH3	Q9UM47-1.2	P2191I	Neutral	0.413
NOTCH3	Q9UM47-1.2	P2191K	Neutral	0.032
NOTCH3	Q9UM47-1.2	P2191L	Neutral	0.413
NOTCH3	Q9UM47-1.2	P2191M	Neutral	0.133
NOTCH3	Q9UM47-1.2	P2191N	Neutral	0.147
NOTCH3	Q9UM47-1.2	P2191Q	Neutral	0.034
NOTCH3	Q9UM47-1.2	P2191R	Neutral	0.124
NOTCH3	Q9UM47-1.2	P2191S	Neutral	0.035
NOTCH3	Q9UM47-1.2	P2191T	Neutral	0.037
NOTCH3	Q9UM47-1.2	P2191V	Neutral	0.142
NOTCH3	Q9UM47-1.2	P2191W	Pathogenic	0.735
NOTCH3	Q9UM47-1.2	P2191Y	Neutral	0.396
NOTCH3	Q9UM47-1.2	G2192A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2192C	Neutral	0.124
NOTCH3	Q9UM47-1.2	G2192D	Neutral	0.007
NOTCH3	Q9UM47-1.2	G2192E	Neutral	0.028
NOTCH3	Q9UM47-1.2	G2192F	Neutral	0.105
NOTCH3	Q9UM47-1.2	G2192H	Neutral	0.027
NOTCH3	Q9UM47-1.2	G2192I	Neutral	0.359
NOTCH3	Q9UM47-1.2	G2192K	Neutral	0.025
NOTCH3	Q9UM47-1.2	G2192L	Neutral	0.359
NOTCH3	Q9UM47-1.2	G2192M	Neutral	0.109
NOTCH3	Q9UM47-1.2	G2192N	Neutral	0.001
NOTCH3	Q9UM47-1.2	G2192P	Neutral	0.03
NOTCH3	Q9UM47-1.2	G2192Q	Neutral	0.027
NOTCH3	Q9UM47-1.2	G2192R	Neutral	0.024
NOTCH3	Q9UM47-1.2	G2192S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2192T	Neutral	0.029
NOTCH3	Q9UM47-1.2	G2192V	Neutral	0.116
NOTCH3	Q9UM47-1.2	G2192W	Neutral	0.023
NOTCH3	Q9UM47-1.2	G2192Y	Neutral	0.103
NOTCH3	Q9UM47-1.2	P2193A	Neutral	0.137
NOTCH3	Q9UM47-1.2	P2193C	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	P2193D	Neutral	0.148
NOTCH3	Q9UM47-1.2	P2193E	Neutral	0.14
NOTCH3	Q9UM47-1.2	P2193F	Pathogenic	0.932
NOTCH3	Q9UM47-1.2	P2193G	Neutral	0.402
NOTCH3	Q9UM47-1.2	P2193H	Neutral	0.415
NOTCH3	Q9UM47-1.2	P2193I	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	P2193K	Neutral	0.128
NOTCH3	Q9UM47-1.2	P2193L	Pathogenic	0.76
NOTCH3	Q9UM47-1.2	P2193M	Neutral	0.409
NOTCH3	Q9UM47-1.2	P2193N	Neutral	0.437
NOTCH3	Q9UM47-1.2	P2193Q	Neutral	0.137
NOTCH3	Q9UM47-1.2	P2193R	Neutral	0.389
NOTCH3	Q9UM47-1.2	P2193S	Neutral	0.14
NOTCH3	Q9UM47-1.2	P2193T	Neutral	0.146
NOTCH3	Q9UM47-1.2	P2193V	Neutral	0.427
NOTCH3	Q9UM47-1.2	P2193W	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	P2193Y	Pathogenic	0.746
NOTCH3	Q9UM47-1.2	Q2194A	Neutral	0.232
NOTCH3	Q9UM47-1.2	Q2194C	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	Q2194D	Neutral	0.068
NOTCH3	Q9UM47-1.2	Q2194E	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q2194F	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	Q2194G	Pathogenic	0.56
NOTCH3	Q9UM47-1.2	Q2194H	Neutral	0.072
NOTCH3	Q9UM47-1.2	Q2194I	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	Q2194K	Neutral	0.016
NOTCH3	Q9UM47-1.2	Q2194L	Pathogenic	0.615
NOTCH3	Q9UM47-1.2	Q2194M	Neutral	0.071
NOTCH3	Q9UM47-1.2	Q2194N	Neutral	0.069
NOTCH3	Q9UM47-1.2	Q2194P	Neutral	0.248
NOTCH3	Q9UM47-1.2	Q2194R	Neutral	0.015
NOTCH3	Q9UM47-1.2	Q2194S	Neutral	0.063
NOTCH3	Q9UM47-1.2	Q2194T	Neutral	0.25
NOTCH3	Q9UM47-1.2	Q2194V	Pathogenic	0.615
NOTCH3	Q9UM47-1.2	Q2194W	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	Q2194Y	Neutral	0.247
NOTCH3	Q9UM47-1.2	L2195A	Neutral	0.009
NOTCH3	Q9UM47-1.2	L2195C	Neutral	0.01
NOTCH3	Q9UM47-1.2	L2195D	Neutral	0.493
NOTCH3	Q9UM47-1.2	L2195E	Neutral	0.186
NOTCH3	Q9UM47-1.2	L2195F	Neutral	0.002
NOTCH3	Q9UM47-1.2	L2195G	Neutral	0.45
NOTCH3	Q9UM47-1.2	L2195H	Neutral	0.19
NOTCH3	Q9UM47-1.2	L2195I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2195K	Neutral	0.049
NOTCH3	Q9UM47-1.2	L2195M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2195N	Neutral	0.179
NOTCH3	Q9UM47-1.2	L2195P	Neutral	0.174
NOTCH3	Q9UM47-1.2	L2195Q	Neutral	0.049
NOTCH3	Q9UM47-1.2	L2195R	Neutral	0.046
NOTCH3	Q9UM47-1.2	L2195S	Neutral	0.042
NOTCH3	Q9UM47-1.2	L2195T	Neutral	0.01
NOTCH3	Q9UM47-1.2	L2195V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2195W	Neutral	0.043
NOTCH3	Q9UM47-1.2	L2195Y	Neutral	0.011
NOTCH3	Q9UM47-1.2	L2196A	Neutral	0.088
NOTCH3	Q9UM47-1.2	L2196C	Neutral	0.094
NOTCH3	Q9UM47-1.2	L2196D	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	L2196E	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	L2196F	Neutral	0.025
NOTCH3	Q9UM47-1.2	L2196G	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	L2196H	Pathogenic	0.71
NOTCH3	Q9UM47-1.2	L2196I	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2196K	Neutral	0.348
NOTCH3	Q9UM47-1.2	L2196M	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2196N	Pathogenic	0.694
NOTCH3	Q9UM47-1.2	L2196P	Pathogenic	0.687
NOTCH3	Q9UM47-1.2	L2196Q	Neutral	0.347
NOTCH3	Q9UM47-1.2	L2196R	Neutral	0.337
NOTCH3	Q9UM47-1.2	L2196S	Neutral	0.312
NOTCH3	Q9UM47-1.2	L2196T	Neutral	0.097
NOTCH3	Q9UM47-1.2	L2196V	Neutral	0.005
NOTCH3	Q9UM47-1.2	L2196W	Neutral	0.32
NOTCH3	Q9UM47-1.2	L2196Y	Neutral	0.101
NOTCH3	Q9UM47-1.2	N2197A	Neutral	0.056
NOTCH3	Q9UM47-1.2	N2197C	Neutral	0.226
NOTCH3	Q9UM47-1.2	N2197D	Neutral	0.001
NOTCH3	Q9UM47-1.2	N2197E	Neutral	0.003
NOTCH3	Q9UM47-1.2	N2197F	Neutral	0.208
NOTCH3	Q9UM47-1.2	N2197G	Neutral	0.003
NOTCH3	Q9UM47-1.2	N2197H	Neutral	0.001
NOTCH3	Q9UM47-1.2	N2197I	Neutral	0.215
NOTCH3	Q9UM47-1.2	N2197K	Neutral	0.003
NOTCH3	Q9UM47-1.2	N2197L	Neutral	0.215
NOTCH3	Q9UM47-1.2	N2197M	Neutral	0.057
NOTCH3	Q9UM47-1.2	N2197P	Neutral	0.061
NOTCH3	Q9UM47-1.2	N2197Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	N2197R	Neutral	0.003
NOTCH3	Q9UM47-1.2	N2197S	Neutral	0.001
NOTCH3	Q9UM47-1.2	N2197T	Neutral	0.003
NOTCH3	Q9UM47-1.2	N2197V	Neutral	0.227
NOTCH3	Q9UM47-1.2	N2197W	Pathogenic	0.519
NOTCH3	Q9UM47-1.2	N2197Y	Neutral	0.053
NOTCH3	Q9UM47-1.2	P2198A	Neutral	0.018
NOTCH3	Q9UM47-1.2	P2198C	Neutral	0.293
NOTCH3	Q9UM47-1.2	P2198D	Neutral	0.02
NOTCH3	Q9UM47-1.2	P2198E	Neutral	0.019
NOTCH3	Q9UM47-1.2	P2198F	Pathogenic	0.619
NOTCH3	Q9UM47-1.2	P2198G	Neutral	0.073
NOTCH3	Q9UM47-1.2	P2198H	Neutral	0.077
NOTCH3	Q9UM47-1.2	P2198I	Neutral	0.271
NOTCH3	Q9UM47-1.2	P2198K	Neutral	0.017
NOTCH3	Q9UM47-1.2	P2198L	Neutral	0.271
NOTCH3	Q9UM47-1.2	P2198M	Neutral	0.075
NOTCH3	Q9UM47-1.2	P2198N	Neutral	0.084
NOTCH3	Q9UM47-1.2	P2198Q	Neutral	0.018
NOTCH3	Q9UM47-1.2	P2198R	Neutral	0.07
NOTCH3	Q9UM47-1.2	P2198S	Neutral	0.019
NOTCH3	Q9UM47-1.2	P2198T	Neutral	0.02
NOTCH3	Q9UM47-1.2	P2198V	Neutral	0.08
NOTCH3	Q9UM47-1.2	P2198W	Pathogenic	0.594
NOTCH3	Q9UM47-1.2	P2198Y	Neutral	0.257
NOTCH3	Q9UM47-1.2	G2199A	Neutral	0.011
NOTCH3	Q9UM47-1.2	G2199C	Neutral	0.499
NOTCH3	Q9UM47-1.2	G2199D	Neutral	0.045
NOTCH3	Q9UM47-1.2	G2199E	Neutral	0.167
NOTCH3	Q9UM47-1.2	G2199F	Neutral	0.454
NOTCH3	Q9UM47-1.2	G2199H	Neutral	0.161
NOTCH3	Q9UM47-1.2	G2199I	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	G2199K	Neutral	0.154
NOTCH3	Q9UM47-1.2	G2199L	Pathogenic	0.798
NOTCH3	Q9UM47-1.2	G2199M	Neutral	0.463
NOTCH3	Q9UM47-1.2	G2199N	Neutral	0.01
NOTCH3	Q9UM47-1.2	G2199P	Neutral	0.177
NOTCH3	Q9UM47-1.2	G2199Q	Neutral	0.164
NOTCH3	Q9UM47-1.2	G2199R	Neutral	0.147
NOTCH3	Q9UM47-1.2	G2199S	Neutral	0.011
NOTCH3	Q9UM47-1.2	G2199T	Neutral	0.175
NOTCH3	Q9UM47-1.2	G2199V	Neutral	0.482
NOTCH3	Q9UM47-1.2	G2199W	Neutral	0.141
NOTCH3	Q9UM47-1.2	G2199Y	Neutral	0.447
NOTCH3	Q9UM47-1.2	T2200A	Neutral	0.002
NOTCH3	Q9UM47-1.2	T2200C	Neutral	0.01
NOTCH3	Q9UM47-1.2	T2200D	Neutral	0.01
NOTCH3	Q9UM47-1.2	T2200E	Neutral	0.009
NOTCH3	Q9UM47-1.2	T2200F	Neutral	0.037
NOTCH3	Q9UM47-1.2	T2200G	Neutral	0.037
NOTCH3	Q9UM47-1.2	T2200H	Neutral	0.039
NOTCH3	Q9UM47-1.2	T2200I	Neutral	0.009
NOTCH3	Q9UM47-1.2	T2200K	Neutral	0.008
NOTCH3	Q9UM47-1.2	T2200L	Neutral	0.009
NOTCH3	Q9UM47-1.2	T2200M	Neutral	0.009
NOTCH3	Q9UM47-1.2	T2200N	Neutral	0.002
NOTCH3	Q9UM47-1.2	T2200P	Neutral	0.01
NOTCH3	Q9UM47-1.2	T2200Q	Neutral	0.009
NOTCH3	Q9UM47-1.2	T2200R	Neutral	0.008
NOTCH3	Q9UM47-1.2	T2200S	Neutral	0.0
NOTCH3	Q9UM47-1.2	T2200V	Neutral	0.002
NOTCH3	Q9UM47-1.2	T2200W	Neutral	0.034
NOTCH3	Q9UM47-1.2	T2200Y	Neutral	0.036
NOTCH3	Q9UM47-1.2	P2201A	Neutral	0.008
NOTCH3	Q9UM47-1.2	P2201C	Neutral	0.145
NOTCH3	Q9UM47-1.2	P2201D	Neutral	0.008
NOTCH3	Q9UM47-1.2	P2201E	Neutral	0.008
NOTCH3	Q9UM47-1.2	P2201F	Neutral	0.398
NOTCH3	Q9UM47-1.2	P2201G	Neutral	0.031
NOTCH3	Q9UM47-1.2	P2201H	Neutral	0.033
NOTCH3	Q9UM47-1.2	P2201I	Neutral	0.132
NOTCH3	Q9UM47-1.2	P2201K	Neutral	0.007
NOTCH3	Q9UM47-1.2	P2201L	Neutral	0.132
NOTCH3	Q9UM47-1.2	P2201M	Neutral	0.032
NOTCH3	Q9UM47-1.2	P2201N	Neutral	0.036
NOTCH3	Q9UM47-1.2	P2201Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	P2201R	Neutral	0.03
NOTCH3	Q9UM47-1.2	P2201S	Neutral	0.008
NOTCH3	Q9UM47-1.2	P2201T	Neutral	0.008
NOTCH3	Q9UM47-1.2	P2201V	Neutral	0.034
NOTCH3	Q9UM47-1.2	P2201W	Neutral	0.374
NOTCH3	Q9UM47-1.2	P2201Y	Neutral	0.124
NOTCH3	Q9UM47-1.2	V2202A	Neutral	0.003
NOTCH3	Q9UM47-1.2	V2202C	Neutral	0.014
NOTCH3	Q9UM47-1.2	V2202D	Neutral	0.227
NOTCH3	Q9UM47-1.2	V2202E	Neutral	0.063
NOTCH3	Q9UM47-1.2	V2202F	Neutral	0.013
NOTCH3	Q9UM47-1.2	V2202G	Neutral	0.198
NOTCH3	Q9UM47-1.2	V2202H	Neutral	0.227
NOTCH3	Q9UM47-1.2	V2202I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V2202K	Neutral	0.057
NOTCH3	Q9UM47-1.2	V2202L	Neutral	0.001
NOTCH3	Q9UM47-1.2	V2202M	Neutral	0.001
NOTCH3	Q9UM47-1.2	V2202N	Neutral	0.23
NOTCH3	Q9UM47-1.2	V2202P	Neutral	0.06
NOTCH3	Q9UM47-1.2	V2202Q	Neutral	0.062
NOTCH3	Q9UM47-1.2	V2202R	Neutral	0.209
NOTCH3	Q9UM47-1.2	V2202S	Neutral	0.057
NOTCH3	Q9UM47-1.2	V2202T	Neutral	0.003
NOTCH3	Q9UM47-1.2	V2202W	Neutral	0.198
NOTCH3	Q9UM47-1.2	V2202Y	Neutral	0.013
NOTCH3	Q9UM47-1.2	S2203A	Neutral	0.002
NOTCH3	Q9UM47-1.2	S2203C	Neutral	0.034
NOTCH3	Q9UM47-1.2	S2203D	Neutral	0.008
NOTCH3	Q9UM47-1.2	S2203E	Neutral	0.007
NOTCH3	Q9UM47-1.2	S2203F	Neutral	0.118
NOTCH3	Q9UM47-1.2	S2203G	Neutral	0.007
NOTCH3	Q9UM47-1.2	S2203H	Neutral	0.03
NOTCH3	Q9UM47-1.2	S2203I	Neutral	0.122
NOTCH3	Q9UM47-1.2	S2203K	Neutral	0.006
NOTCH3	Q9UM47-1.2	S2203L	Neutral	0.122
NOTCH3	Q9UM47-1.2	S2203M	Neutral	0.03
NOTCH3	Q9UM47-1.2	S2203N	Neutral	0.002
NOTCH3	Q9UM47-1.2	S2203P	Neutral	0.033
NOTCH3	Q9UM47-1.2	S2203Q	Neutral	0.007
NOTCH3	Q9UM47-1.2	S2203R	Neutral	0.027
NOTCH3	Q9UM47-1.2	S2203T	Neutral	0.002
NOTCH3	Q9UM47-1.2	S2203V	Neutral	0.13
NOTCH3	Q9UM47-1.2	S2203W	Neutral	0.354
NOTCH3	Q9UM47-1.2	S2203Y	Neutral	0.115
NOTCH3	Q9UM47-1.2	P2204A	Neutral	0.077
NOTCH3	Q9UM47-1.2	P2204C	Pathogenic	0.652
NOTCH3	Q9UM47-1.2	P2204D	Neutral	0.084
NOTCH3	Q9UM47-1.2	P2204E	Neutral	0.079
NOTCH3	Q9UM47-1.2	P2204F	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	P2204G	Neutral	0.263
NOTCH3	Q9UM47-1.2	P2204H	Neutral	0.273
NOTCH3	Q9UM47-1.2	P2204I	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	P2204K	Neutral	0.072
NOTCH3	Q9UM47-1.2	P2204L	Pathogenic	0.626
NOTCH3	Q9UM47-1.2	P2204M	Neutral	0.268
NOTCH3	Q9UM47-1.2	P2204N	Neutral	0.291
NOTCH3	Q9UM47-1.2	P2204Q	Neutral	0.078
NOTCH3	Q9UM47-1.2	P2204R	Neutral	0.252
NOTCH3	Q9UM47-1.2	P2204S	Neutral	0.079
NOTCH3	Q9UM47-1.2	P2204T	Neutral	0.083
NOTCH3	Q9UM47-1.2	P2204V	Neutral	0.283
NOTCH3	Q9UM47-1.2	P2204W	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	P2204Y	Pathogenic	0.609
NOTCH3	Q9UM47-1.2	Q2205A	Neutral	0.246
NOTCH3	Q9UM47-1.2	Q2205C	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	Q2205D	Neutral	0.073
NOTCH3	Q9UM47-1.2	Q2205E	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q2205F	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	Q2205G	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	Q2205H	Neutral	0.078
NOTCH3	Q9UM47-1.2	Q2205I	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	Q2205K	Neutral	0.017
NOTCH3	Q9UM47-1.2	Q2205L	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	Q2205M	Neutral	0.077
NOTCH3	Q9UM47-1.2	Q2205N	Neutral	0.074
NOTCH3	Q9UM47-1.2	Q2205P	Neutral	0.264
NOTCH3	Q9UM47-1.2	Q2205R	Neutral	0.016
NOTCH3	Q9UM47-1.2	Q2205S	Neutral	0.068
NOTCH3	Q9UM47-1.2	Q2205T	Neutral	0.265
NOTCH3	Q9UM47-1.2	Q2205V	Pathogenic	0.634
NOTCH3	Q9UM47-1.2	Q2205W	Pathogenic	0.6
NOTCH3	Q9UM47-1.2	Q2205Y	Neutral	0.262
NOTCH3	Q9UM47-1.2	E2206A	Neutral	0.012
NOTCH3	Q9UM47-1.2	E2206C	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	E2206D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E2206F	Neutral	0.21
NOTCH3	Q9UM47-1.2	E2206G	Neutral	0.048
NOTCH3	Q9UM47-1.2	E2206H	Neutral	0.003
NOTCH3	Q9UM47-1.2	E2206I	Neutral	0.217
NOTCH3	Q9UM47-1.2	E2206K	Neutral	0.001
NOTCH3	Q9UM47-1.2	E2206L	Neutral	0.217
NOTCH3	Q9UM47-1.2	E2206M	Neutral	0.057
NOTCH3	Q9UM47-1.2	E2206N	Neutral	0.003
NOTCH3	Q9UM47-1.2	E2206P	Neutral	0.013
NOTCH3	Q9UM47-1.2	E2206Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E2206R	Neutral	0.003
NOTCH3	Q9UM47-1.2	E2206S	Neutral	0.003
NOTCH3	Q9UM47-1.2	E2206T	Neutral	0.013
NOTCH3	Q9UM47-1.2	E2206V	Neutral	0.059
NOTCH3	Q9UM47-1.2	E2206W	Neutral	0.193
NOTCH3	Q9UM47-1.2	E2206Y	Neutral	0.054
NOTCH3	Q9UM47-1.2	R2207A	Neutral	0.017
NOTCH3	Q9UM47-1.2	R2207C	Neutral	0.278
NOTCH3	Q9UM47-1.2	R2207D	Neutral	0.078
NOTCH3	Q9UM47-1.2	R2207E	Neutral	0.004
NOTCH3	Q9UM47-1.2	R2207F	Neutral	0.319
NOTCH3	Q9UM47-1.2	R2207G	Neutral	0.067
NOTCH3	Q9UM47-1.2	R2207H	Neutral	0.005
NOTCH3	Q9UM47-1.2	R2207I	Neutral	0.31
NOTCH3	Q9UM47-1.2	R2207K	Neutral	0.0
NOTCH3	Q9UM47-1.2	R2207L	Neutral	0.09
NOTCH3	Q9UM47-1.2	R2207M	Neutral	0.021
NOTCH3	Q9UM47-1.2	R2207N	Neutral	0.004
NOTCH3	Q9UM47-1.2	R2207P	Neutral	0.079
NOTCH3	Q9UM47-1.2	R2207Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	R2207S	Neutral	0.017
NOTCH3	Q9UM47-1.2	R2207T	Neutral	0.019
NOTCH3	Q9UM47-1.2	R2207V	Neutral	0.293
NOTCH3	Q9UM47-1.2	R2207W	Neutral	0.318
NOTCH3	Q9UM47-1.2	R2207Y	Neutral	0.095
NOTCH3	Q9UM47-1.2	P2208A	Neutral	0.043
NOTCH3	Q9UM47-1.2	P2208C	Pathogenic	0.501
NOTCH3	Q9UM47-1.2	P2208D	Neutral	0.047
NOTCH3	Q9UM47-1.2	P2208E	Neutral	0.044
NOTCH3	Q9UM47-1.2	P2208F	Pathogenic	0.797
NOTCH3	Q9UM47-1.2	P2208G	Neutral	0.16
NOTCH3	Q9UM47-1.2	P2208H	Neutral	0.168
NOTCH3	Q9UM47-1.2	P2208I	Neutral	0.474
NOTCH3	Q9UM47-1.2	P2208K	Neutral	0.04
NOTCH3	Q9UM47-1.2	P2208L	Neutral	0.473
NOTCH3	Q9UM47-1.2	P2208M	Neutral	0.164
NOTCH3	Q9UM47-1.2	P2208N	Neutral	0.181
NOTCH3	Q9UM47-1.2	P2208Q	Neutral	0.043
NOTCH3	Q9UM47-1.2	P2208R	Neutral	0.153
NOTCH3	Q9UM47-1.2	P2208S	Neutral	0.044
NOTCH3	Q9UM47-1.2	P2208T	Neutral	0.046
NOTCH3	Q9UM47-1.2	P2208V	Neutral	0.175
NOTCH3	Q9UM47-1.2	P2208W	Pathogenic	0.78
NOTCH3	Q9UM47-1.2	P2208Y	Neutral	0.456
NOTCH3	Q9UM47-1.2	P2209A	Neutral	0.095
NOTCH3	Q9UM47-1.2	P2209C	Pathogenic	0.702
NOTCH3	Q9UM47-1.2	P2209D	Neutral	0.104
NOTCH3	Q9UM47-1.2	P2209E	Neutral	0.097
NOTCH3	Q9UM47-1.2	P2209F	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	P2209G	Neutral	0.309
NOTCH3	Q9UM47-1.2	P2209H	Neutral	0.321
NOTCH3	Q9UM47-1.2	P2209I	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	P2209K	Neutral	0.089
NOTCH3	Q9UM47-1.2	P2209L	Pathogenic	0.678
NOTCH3	Q9UM47-1.2	P2209M	Neutral	0.315
NOTCH3	Q9UM47-1.2	P2209N	Neutral	0.341
NOTCH3	Q9UM47-1.2	P2209Q	Neutral	0.096
NOTCH3	Q9UM47-1.2	P2209R	Neutral	0.298
NOTCH3	Q9UM47-1.2	P2209S	Neutral	0.098
NOTCH3	Q9UM47-1.2	P2209T	Neutral	0.102
NOTCH3	Q9UM47-1.2	P2209V	Neutral	0.331
NOTCH3	Q9UM47-1.2	P2209W	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	P2209Y	Pathogenic	0.662
NOTCH3	Q9UM47-1.2	P2210A	Neutral	0.233
NOTCH3	Q9UM47-1.2	P2210C	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	P2210D	Neutral	0.25
NOTCH3	Q9UM47-1.2	P2210E	Neutral	0.237
NOTCH3	Q9UM47-1.2	P2210F	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	P2210G	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	P2210H	Pathogenic	0.576
NOTCH3	Q9UM47-1.2	P2210I	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	P2210K	Neutral	0.22
NOTCH3	Q9UM47-1.2	P2210L	Pathogenic	0.858
NOTCH3	Q9UM47-1.2	P2210M	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	P2210N	Pathogenic	0.598
NOTCH3	Q9UM47-1.2	P2210Q	Neutral	0.233
NOTCH3	Q9UM47-1.2	P2210R	Pathogenic	0.55
NOTCH3	Q9UM47-1.2	P2210S	Neutral	0.238
NOTCH3	Q9UM47-1.2	P2210T	Neutral	0.247
NOTCH3	Q9UM47-1.2	P2210V	Pathogenic	0.588
NOTCH3	Q9UM47-1.2	P2210W	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	P2210Y	Pathogenic	0.849
NOTCH3	Q9UM47-1.2	Y2211A	Neutral	0.156
NOTCH3	Q9UM47-1.2	Y2211C	Neutral	0.165
NOTCH3	Q9UM47-1.2	Y2211D	Neutral	0.481
NOTCH3	Q9UM47-1.2	Y2211E	Neutral	0.179
NOTCH3	Q9UM47-1.2	Y2211F	Neutral	0.0
NOTCH3	Q9UM47-1.2	Y2211G	Neutral	0.439
NOTCH3	Q9UM47-1.2	Y2211H	Neutral	0.001
NOTCH3	Q9UM47-1.2	Y2211I	Neutral	0.048
NOTCH3	Q9UM47-1.2	Y2211K	Neutral	0.195
NOTCH3	Q9UM47-1.2	Y2211L	Neutral	0.048
NOTCH3	Q9UM47-1.2	Y2211M	Neutral	0.048
NOTCH3	Q9UM47-1.2	Y2211N	Neutral	0.172
NOTCH3	Q9UM47-1.2	Y2211P	Neutral	0.477
NOTCH3	Q9UM47-1.2	Y2211Q	Neutral	0.046
NOTCH3	Q9UM47-1.2	Y2211R	Neutral	0.194
NOTCH3	Q9UM47-1.2	Y2211S	Neutral	0.159
NOTCH3	Q9UM47-1.2	Y2211T	Neutral	0.169
NOTCH3	Q9UM47-1.2	Y2211V	Neutral	0.045
NOTCH3	Q9UM47-1.2	Y2211W	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2212A	Neutral	0.02
NOTCH3	Q9UM47-1.2	L2212C	Neutral	0.021
NOTCH3	Q9UM47-1.2	L2212D	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	L2212E	Neutral	0.33
NOTCH3	Q9UM47-1.2	L2212F	Neutral	0.005
NOTCH3	Q9UM47-1.2	L2212G	Pathogenic	0.638
NOTCH3	Q9UM47-1.2	L2212H	Neutral	0.337
NOTCH3	Q9UM47-1.2	L2212I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2212K	Neutral	0.099
NOTCH3	Q9UM47-1.2	L2212M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2212N	Neutral	0.319
NOTCH3	Q9UM47-1.2	L2212P	Neutral	0.312
NOTCH3	Q9UM47-1.2	L2212Q	Neutral	0.099
NOTCH3	Q9UM47-1.2	L2212R	Neutral	0.095
NOTCH3	Q9UM47-1.2	L2212S	Neutral	0.086
NOTCH3	Q9UM47-1.2	L2212T	Neutral	0.022
NOTCH3	Q9UM47-1.2	L2212V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2212W	Neutral	0.089
NOTCH3	Q9UM47-1.2	L2212Y	Neutral	0.023
NOTCH3	Q9UM47-1.2	A2213C	Neutral	0.027
NOTCH3	Q9UM47-1.2	A2213D	Neutral	0.359
NOTCH3	Q9UM47-1.2	A2213E	Neutral	0.103
NOTCH3	Q9UM47-1.2	A2213F	Neutral	0.321
NOTCH3	Q9UM47-1.2	A2213G	Neutral	0.027
NOTCH3	Q9UM47-1.2	A2213H	Neutral	0.333
NOTCH3	Q9UM47-1.2	A2213I	Neutral	0.098
NOTCH3	Q9UM47-1.2	A2213K	Neutral	0.094
NOTCH3	Q9UM47-1.2	A2213L	Neutral	0.098
NOTCH3	Q9UM47-1.2	A2213M	Neutral	0.097
NOTCH3	Q9UM47-1.2	A2213N	Neutral	0.354
NOTCH3	Q9UM47-1.2	A2213P	Neutral	0.109
NOTCH3	Q9UM47-1.2	A2213Q	Neutral	0.101
NOTCH3	Q9UM47-1.2	A2213R	Neutral	0.09
NOTCH3	Q9UM47-1.2	A2213S	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2213T	Neutral	0.026
NOTCH3	Q9UM47-1.2	A2213V	Neutral	0.025
NOTCH3	Q9UM47-1.2	A2213W	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	A2213Y	Neutral	0.315
NOTCH3	Q9UM47-1.2	V2214A	Neutral	0.001
NOTCH3	Q9UM47-1.2	V2214C	Neutral	0.003
NOTCH3	Q9UM47-1.2	V2214D	Neutral	0.058
NOTCH3	Q9UM47-1.2	V2214E	Neutral	0.014
NOTCH3	Q9UM47-1.2	V2214F	Neutral	0.003
NOTCH3	Q9UM47-1.2	V2214G	Neutral	0.049
NOTCH3	Q9UM47-1.2	V2214H	Neutral	0.057
NOTCH3	Q9UM47-1.2	V2214I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V2214K	Neutral	0.012
NOTCH3	Q9UM47-1.2	V2214L	Neutral	0.0
NOTCH3	Q9UM47-1.2	V2214M	Neutral	0.0
NOTCH3	Q9UM47-1.2	V2214N	Neutral	0.058
NOTCH3	Q9UM47-1.2	V2214P	Neutral	0.013
NOTCH3	Q9UM47-1.2	V2214Q	Neutral	0.013
NOTCH3	Q9UM47-1.2	V2214R	Neutral	0.052
NOTCH3	Q9UM47-1.2	V2214S	Neutral	0.012
NOTCH3	Q9UM47-1.2	V2214T	Neutral	0.001
NOTCH3	Q9UM47-1.2	V2214W	Neutral	0.049
NOTCH3	Q9UM47-1.2	V2214Y	Neutral	0.003
NOTCH3	Q9UM47-1.2	P2215A	Neutral	0.011
NOTCH3	Q9UM47-1.2	P2215C	Neutral	0.202
NOTCH3	Q9UM47-1.2	P2215D	Neutral	0.012
NOTCH3	Q9UM47-1.2	P2215E	Neutral	0.011
NOTCH3	Q9UM47-1.2	P2215F	Neutral	0.497
NOTCH3	Q9UM47-1.2	P2215G	Neutral	0.046
NOTCH3	Q9UM47-1.2	P2215H	Neutral	0.048
NOTCH3	Q9UM47-1.2	P2215I	Neutral	0.185
NOTCH3	Q9UM47-1.2	P2215K	Neutral	0.01
NOTCH3	Q9UM47-1.2	P2215L	Neutral	0.184
NOTCH3	Q9UM47-1.2	P2215M	Neutral	0.047
NOTCH3	Q9UM47-1.2	P2215N	Neutral	0.053
NOTCH3	Q9UM47-1.2	P2215Q	Neutral	0.011
NOTCH3	Q9UM47-1.2	P2215R	Neutral	0.044
NOTCH3	Q9UM47-1.2	P2215S	Neutral	0.012
NOTCH3	Q9UM47-1.2	P2215T	Neutral	0.012
NOTCH3	Q9UM47-1.2	P2215V	Neutral	0.051
NOTCH3	Q9UM47-1.2	P2215W	Neutral	0.471
NOTCH3	Q9UM47-1.2	P2215Y	Neutral	0.174
NOTCH3	Q9UM47-1.2	G2216A	Neutral	0.029
NOTCH3	Q9UM47-1.2	G2216C	Pathogenic	0.726
NOTCH3	Q9UM47-1.2	G2216D	Neutral	0.111
NOTCH3	Q9UM47-1.2	G2216E	Neutral	0.347
NOTCH3	Q9UM47-1.2	G2216F	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	G2216H	Neutral	0.338
NOTCH3	Q9UM47-1.2	G2216I	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	G2216K	Neutral	0.325
NOTCH3	Q9UM47-1.2	G2216L	Pathogenic	0.913
NOTCH3	Q9UM47-1.2	G2216M	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	G2216N	Neutral	0.026
NOTCH3	Q9UM47-1.2	G2216P	Neutral	0.364
NOTCH3	Q9UM47-1.2	G2216Q	Neutral	0.342
NOTCH3	Q9UM47-1.2	G2216R	Neutral	0.314
NOTCH3	Q9UM47-1.2	G2216S	Neutral	0.028
NOTCH3	Q9UM47-1.2	G2216T	Neutral	0.36
NOTCH3	Q9UM47-1.2	G2216V	Pathogenic	0.711
NOTCH3	Q9UM47-1.2	G2216W	Neutral	0.304
NOTCH3	Q9UM47-1.2	G2216Y	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	H2217A	Pathogenic	0.5
NOTCH3	Q9UM47-1.2	H2217C	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	H2217D	Neutral	0.195
NOTCH3	Q9UM47-1.2	H2217E	Neutral	0.054
NOTCH3	Q9UM47-1.2	H2217F	Neutral	0.202
NOTCH3	Q9UM47-1.2	H2217G	Neutral	0.482
NOTCH3	Q9UM47-1.2	H2217I	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	H2217K	Neutral	0.202
NOTCH3	Q9UM47-1.2	H2217L	Pathogenic	0.846
NOTCH3	Q9UM47-1.2	H2217M	Pathogenic	0.546
NOTCH3	Q9UM47-1.2	H2217N	Neutral	0.012
NOTCH3	Q9UM47-1.2	H2217P	Pathogenic	0.523
NOTCH3	Q9UM47-1.2	H2217Q	Neutral	0.055
NOTCH3	Q9UM47-1.2	H2217R	Neutral	0.05
NOTCH3	Q9UM47-1.2	H2217S	Neutral	0.184
NOTCH3	Q9UM47-1.2	H2217T	Pathogenic	0.525
NOTCH3	Q9UM47-1.2	H2217V	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	H2217W	Pathogenic	0.51
NOTCH3	Q9UM47-1.2	H2217Y	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2218A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2218C	Neutral	0.163
NOTCH3	Q9UM47-1.2	G2218D	Neutral	0.009
NOTCH3	Q9UM47-1.2	G2218E	Neutral	0.038
NOTCH3	Q9UM47-1.2	G2218F	Neutral	0.14
NOTCH3	Q9UM47-1.2	G2218H	Neutral	0.036
NOTCH3	Q9UM47-1.2	G2218I	Neutral	0.436
NOTCH3	Q9UM47-1.2	G2218K	Neutral	0.034
NOTCH3	Q9UM47-1.2	G2218L	Neutral	0.436
NOTCH3	Q9UM47-1.2	G2218M	Neutral	0.145
NOTCH3	Q9UM47-1.2	G2218N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2218P	Neutral	0.04
NOTCH3	Q9UM47-1.2	G2218Q	Neutral	0.037
NOTCH3	Q9UM47-1.2	G2218R	Neutral	0.033
NOTCH3	Q9UM47-1.2	G2218S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2218T	Neutral	0.04
NOTCH3	Q9UM47-1.2	G2218V	Neutral	0.154
NOTCH3	Q9UM47-1.2	G2218W	Neutral	0.031
NOTCH3	Q9UM47-1.2	G2218Y	Neutral	0.136
NOTCH3	Q9UM47-1.2	E2219A	Neutral	0.026
NOTCH3	Q9UM47-1.2	E2219C	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	E2219D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E2219F	Neutral	0.376
NOTCH3	Q9UM47-1.2	E2219G	Neutral	0.102
NOTCH3	Q9UM47-1.2	E2219H	Neutral	0.007
NOTCH3	Q9UM47-1.2	E2219I	Neutral	0.386
NOTCH3	Q9UM47-1.2	E2219K	Neutral	0.001
NOTCH3	Q9UM47-1.2	E2219L	Neutral	0.386
NOTCH3	Q9UM47-1.2	E2219M	Neutral	0.121
NOTCH3	Q9UM47-1.2	E2219N	Neutral	0.007
NOTCH3	Q9UM47-1.2	E2219P	Neutral	0.029
NOTCH3	Q9UM47-1.2	E2219Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E2219R	Neutral	0.006
NOTCH3	Q9UM47-1.2	E2219S	Neutral	0.006
NOTCH3	Q9UM47-1.2	E2219T	Neutral	0.029
NOTCH3	Q9UM47-1.2	E2219V	Neutral	0.125
NOTCH3	Q9UM47-1.2	E2219W	Neutral	0.352
NOTCH3	Q9UM47-1.2	E2219Y	Neutral	0.114
NOTCH3	Q9UM47-1.2	E2220A	Neutral	0.019
NOTCH3	Q9UM47-1.2	E2220C	Pathogenic	0.667
NOTCH3	Q9UM47-1.2	E2220D	Neutral	0.0
NOTCH3	Q9UM47-1.2	E2220F	Neutral	0.305
NOTCH3	Q9UM47-1.2	E2220G	Neutral	0.077
NOTCH3	Q9UM47-1.2	E2220H	Neutral	0.005
NOTCH3	Q9UM47-1.2	E2220I	Neutral	0.314
NOTCH3	Q9UM47-1.2	E2220K	Neutral	0.001
NOTCH3	Q9UM47-1.2	E2220L	Neutral	0.314
NOTCH3	Q9UM47-1.2	E2220M	Neutral	0.091
NOTCH3	Q9UM47-1.2	E2220N	Neutral	0.005
NOTCH3	Q9UM47-1.2	E2220P	Neutral	0.021
NOTCH3	Q9UM47-1.2	E2220Q	Neutral	0.0
NOTCH3	Q9UM47-1.2	E2220R	Neutral	0.004
NOTCH3	Q9UM47-1.2	E2220S	Neutral	0.004
NOTCH3	Q9UM47-1.2	E2220T	Neutral	0.021
NOTCH3	Q9UM47-1.2	E2220V	Neutral	0.094
NOTCH3	Q9UM47-1.2	E2220W	Neutral	0.283
NOTCH3	Q9UM47-1.2	E2220Y	Neutral	0.085
NOTCH3	Q9UM47-1.2	Y2221A	Pathogenic	0.867
NOTCH3	Q9UM47-1.2	Y2221C	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	Y2221D	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	Y2221E	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	Y2221F	Neutral	0.004
NOTCH3	Q9UM47-1.2	Y2221G	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	Y2221H	Neutral	0.018
NOTCH3	Q9UM47-1.2	Y2221I	Pathogenic	0.641
NOTCH3	Q9UM47-1.2	Y2221K	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	Y2221L	Pathogenic	0.641
NOTCH3	Q9UM47-1.2	Y2221M	Pathogenic	0.64
NOTCH3	Q9UM47-1.2	Y2221N	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	Y2221P	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	Y2221Q	Pathogenic	0.633
NOTCH3	Q9UM47-1.2	Y2221R	Pathogenic	0.895
NOTCH3	Q9UM47-1.2	Y2221S	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	Y2221T	Pathogenic	0.878
NOTCH3	Q9UM47-1.2	Y2221V	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	Y2221W	Neutral	0.018
NOTCH3	Q9UM47-1.2	P2222A	Neutral	0.199
NOTCH3	Q9UM47-1.2	P2222C	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	P2222D	Neutral	0.214
NOTCH3	Q9UM47-1.2	P2222E	Neutral	0.202
NOTCH3	Q9UM47-1.2	P2222F	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	P2222G	Pathogenic	0.512
NOTCH3	Q9UM47-1.2	P2222H	Pathogenic	0.526
NOTCH3	Q9UM47-1.2	P2222I	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	P2222K	Neutral	0.187
NOTCH3	Q9UM47-1.2	P2222L	Pathogenic	0.832
NOTCH3	Q9UM47-1.2	P2222M	Pathogenic	0.52
NOTCH3	Q9UM47-1.2	P2222N	Pathogenic	0.548
NOTCH3	Q9UM47-1.2	P2222Q	Neutral	0.199
NOTCH3	Q9UM47-1.2	P2222R	Neutral	0.499
NOTCH3	Q9UM47-1.2	P2222S	Neutral	0.203
NOTCH3	Q9UM47-1.2	P2222T	Neutral	0.211
NOTCH3	Q9UM47-1.2	P2222V	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	P2222W	Pathogenic	0.951
NOTCH3	Q9UM47-1.2	P2222Y	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	A2223C	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2223D	Neutral	0.117
NOTCH3	Q9UM47-1.2	A2223E	Neutral	0.026
NOTCH3	Q9UM47-1.2	A2223F	Neutral	0.101
NOTCH3	Q9UM47-1.2	A2223G	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2223H	Neutral	0.106
NOTCH3	Q9UM47-1.2	A2223I	Neutral	0.025
NOTCH3	Q9UM47-1.2	A2223K	Neutral	0.024
NOTCH3	Q9UM47-1.2	A2223L	Neutral	0.025
NOTCH3	Q9UM47-1.2	A2223M	Neutral	0.025
NOTCH3	Q9UM47-1.2	A2223N	Neutral	0.115
NOTCH3	Q9UM47-1.2	A2223P	Neutral	0.028
NOTCH3	Q9UM47-1.2	A2223Q	Neutral	0.026
NOTCH3	Q9UM47-1.2	A2223R	Neutral	0.023
NOTCH3	Q9UM47-1.2	A2223S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2223T	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2223V	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2223W	Neutral	0.314
NOTCH3	Q9UM47-1.2	A2223Y	Neutral	0.098
NOTCH3	Q9UM47-1.2	A2224C	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2224D	Neutral	0.105
NOTCH3	Q9UM47-1.2	A2224E	Neutral	0.024
NOTCH3	Q9UM47-1.2	A2224F	Neutral	0.091
NOTCH3	Q9UM47-1.2	A2224G	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2224H	Neutral	0.095
NOTCH3	Q9UM47-1.2	A2224I	Neutral	0.022
NOTCH3	Q9UM47-1.2	A2224K	Neutral	0.021
NOTCH3	Q9UM47-1.2	A2224L	Neutral	0.022
NOTCH3	Q9UM47-1.2	A2224M	Neutral	0.022
NOTCH3	Q9UM47-1.2	A2224N	Neutral	0.103
NOTCH3	Q9UM47-1.2	A2224P	Neutral	0.025
NOTCH3	Q9UM47-1.2	A2224Q	Neutral	0.023
NOTCH3	Q9UM47-1.2	A2224R	Neutral	0.02
NOTCH3	Q9UM47-1.2	A2224S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2224T	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2224V	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2224W	Neutral	0.29
NOTCH3	Q9UM47-1.2	A2224Y	Neutral	0.088
NOTCH3	Q9UM47-1.2	G2225A	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2225C	Neutral	0.21
NOTCH3	Q9UM47-1.2	G2225D	Neutral	0.012
NOTCH3	Q9UM47-1.2	G2225E	Neutral	0.051
NOTCH3	Q9UM47-1.2	G2225F	Neutral	0.181
NOTCH3	Q9UM47-1.2	G2225H	Neutral	0.049
NOTCH3	Q9UM47-1.2	G2225I	Pathogenic	0.513
NOTCH3	Q9UM47-1.2	G2225K	Neutral	0.046
NOTCH3	Q9UM47-1.2	G2225L	Pathogenic	0.512
NOTCH3	Q9UM47-1.2	G2225M	Neutral	0.187
NOTCH3	Q9UM47-1.2	G2225N	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2225P	Neutral	0.054
NOTCH3	Q9UM47-1.2	G2225Q	Neutral	0.049
NOTCH3	Q9UM47-1.2	G2225R	Neutral	0.044
NOTCH3	Q9UM47-1.2	G2225S	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2225T	Neutral	0.053
NOTCH3	Q9UM47-1.2	G2225V	Neutral	0.198
NOTCH3	Q9UM47-1.2	G2225W	Neutral	0.042
NOTCH3	Q9UM47-1.2	G2225Y	Neutral	0.177
NOTCH3	Q9UM47-1.2	A2226C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2226D	Neutral	0.053
NOTCH3	Q9UM47-1.2	A2226E	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2226F	Neutral	0.046
NOTCH3	Q9UM47-1.2	A2226G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2226H	Neutral	0.048
NOTCH3	Q9UM47-1.2	A2226I	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2226K	Neutral	0.01
NOTCH3	Q9UM47-1.2	A2226L	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2226M	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2226N	Neutral	0.052
NOTCH3	Q9UM47-1.2	A2226P	Neutral	0.012
NOTCH3	Q9UM47-1.2	A2226Q	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2226R	Neutral	0.01
NOTCH3	Q9UM47-1.2	A2226S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2226T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2226V	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2226W	Neutral	0.164
NOTCH3	Q9UM47-1.2	A2226Y	Neutral	0.044
NOTCH3	Q9UM47-1.2	H2227A	Pathogenic	0.958
NOTCH3	Q9UM47-1.2	H2227C	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	H2227D	Pathogenic	0.847
NOTCH3	Q9UM47-1.2	H2227E	Pathogenic	0.566
NOTCH3	Q9UM47-1.2	H2227F	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	H2227G	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	H2227I	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	H2227K	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	H2227L	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	H2227M	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	H2227N	Neutral	0.214
NOTCH3	Q9UM47-1.2	H2227P	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	H2227Q	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	H2227R	Pathogenic	0.547
NOTCH3	Q9UM47-1.2	H2227S	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	H2227T	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	H2227V	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	H2227W	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	H2227Y	Neutral	0.056
NOTCH3	Q9UM47-1.2	S2228A	Neutral	0.045
NOTCH3	Q9UM47-1.2	S2228C	Neutral	0.486
NOTCH3	Q9UM47-1.2	S2228D	Neutral	0.169
NOTCH3	Q9UM47-1.2	S2228E	Neutral	0.159
NOTCH3	Q9UM47-1.2	S2228F	Pathogenic	0.782
NOTCH3	Q9UM47-1.2	S2228G	Neutral	0.164
NOTCH3	Q9UM47-1.2	S2228H	Neutral	0.453
NOTCH3	Q9UM47-1.2	S2228I	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	S2228K	Neutral	0.147
NOTCH3	Q9UM47-1.2	S2228L	Pathogenic	0.789
NOTCH3	Q9UM47-1.2	S2228M	Neutral	0.45
NOTCH3	Q9UM47-1.2	S2228N	Neutral	0.042
NOTCH3	Q9UM47-1.2	S2228P	Neutral	0.481
NOTCH3	Q9UM47-1.2	S2228Q	Neutral	0.156
NOTCH3	Q9UM47-1.2	S2228R	Neutral	0.426
NOTCH3	Q9UM47-1.2	S2228T	Neutral	0.042
NOTCH3	Q9UM47-1.2	S2228V	Pathogenic	0.8
NOTCH3	Q9UM47-1.2	S2228W	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	S2228Y	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	S2229A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2229C	Neutral	0.013
NOTCH3	Q9UM47-1.2	S2229D	Neutral	0.003
NOTCH3	Q9UM47-1.2	S2229E	Neutral	0.003
NOTCH3	Q9UM47-1.2	S2229F	Neutral	0.049
NOTCH3	Q9UM47-1.2	S2229G	Neutral	0.003
NOTCH3	Q9UM47-1.2	S2229H	Neutral	0.012
NOTCH3	Q9UM47-1.2	S2229I	Neutral	0.051
NOTCH3	Q9UM47-1.2	S2229K	Neutral	0.002
NOTCH3	Q9UM47-1.2	S2229L	Neutral	0.051
NOTCH3	Q9UM47-1.2	S2229M	Neutral	0.012
NOTCH3	Q9UM47-1.2	S2229N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2229P	Neutral	0.013
NOTCH3	Q9UM47-1.2	S2229Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	S2229R	Neutral	0.011
NOTCH3	Q9UM47-1.2	S2229T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2229V	Neutral	0.055
NOTCH3	Q9UM47-1.2	S2229W	Neutral	0.175
NOTCH3	Q9UM47-1.2	S2229Y	Neutral	0.048
NOTCH3	Q9UM47-1.2	P2230A	Neutral	0.008
NOTCH3	Q9UM47-1.2	P2230C	Neutral	0.159
NOTCH3	Q9UM47-1.2	P2230D	Neutral	0.009
NOTCH3	Q9UM47-1.2	P2230E	Neutral	0.009
NOTCH3	Q9UM47-1.2	P2230F	Neutral	0.424
NOTCH3	Q9UM47-1.2	P2230G	Neutral	0.035
NOTCH3	Q9UM47-1.2	P2230H	Neutral	0.036
NOTCH3	Q9UM47-1.2	P2230I	Neutral	0.145
NOTCH3	Q9UM47-1.2	P2230K	Neutral	0.008
NOTCH3	Q9UM47-1.2	P2230L	Neutral	0.144
NOTCH3	Q9UM47-1.2	P2230M	Neutral	0.036
NOTCH3	Q9UM47-1.2	P2230N	Neutral	0.04
NOTCH3	Q9UM47-1.2	P2230Q	Neutral	0.008
NOTCH3	Q9UM47-1.2	P2230R	Neutral	0.033
NOTCH3	Q9UM47-1.2	P2230S	Neutral	0.009
NOTCH3	Q9UM47-1.2	P2230T	Neutral	0.009
NOTCH3	Q9UM47-1.2	P2230V	Neutral	0.038
NOTCH3	Q9UM47-1.2	P2230W	Neutral	0.399
NOTCH3	Q9UM47-1.2	P2230Y	Neutral	0.136
NOTCH3	Q9UM47-1.2	P2231A	Neutral	0.017
NOTCH3	Q9UM47-1.2	P2231C	Neutral	0.275
NOTCH3	Q9UM47-1.2	P2231D	Neutral	0.018
NOTCH3	Q9UM47-1.2	P2231E	Neutral	0.017
NOTCH3	Q9UM47-1.2	P2231F	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	P2231G	Neutral	0.067
NOTCH3	Q9UM47-1.2	P2231H	Neutral	0.071
NOTCH3	Q9UM47-1.2	P2231I	Neutral	0.254
NOTCH3	Q9UM47-1.2	P2231K	Neutral	0.016
NOTCH3	Q9UM47-1.2	P2231L	Neutral	0.254
NOTCH3	Q9UM47-1.2	P2231M	Neutral	0.069
NOTCH3	Q9UM47-1.2	P2231N	Neutral	0.077
NOTCH3	Q9UM47-1.2	P2231Q	Neutral	0.017
NOTCH3	Q9UM47-1.2	P2231R	Neutral	0.064
NOTCH3	Q9UM47-1.2	P2231S	Neutral	0.017
NOTCH3	Q9UM47-1.2	P2231T	Neutral	0.018
NOTCH3	Q9UM47-1.2	P2231V	Neutral	0.074
NOTCH3	Q9UM47-1.2	P2231W	Pathogenic	0.572
NOTCH3	Q9UM47-1.2	P2231Y	Neutral	0.24
NOTCH3	Q9UM47-1.2	K2232A	Neutral	0.142
NOTCH3	Q9UM47-1.2	K2232C	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	K2232D	Neutral	0.152
NOTCH3	Q9UM47-1.2	K2232E	Neutral	0.009
NOTCH3	Q9UM47-1.2	K2232F	Pathogenic	0.818
NOTCH3	Q9UM47-1.2	K2232G	Neutral	0.411
NOTCH3	Q9UM47-1.2	K2232H	Neutral	0.167
NOTCH3	Q9UM47-1.2	K2232I	Pathogenic	0.812
NOTCH3	Q9UM47-1.2	K2232L	Neutral	0.486
NOTCH3	Q9UM47-1.2	K2232M	Neutral	0.172
NOTCH3	Q9UM47-1.2	K2232N	Neutral	0.039
NOTCH3	Q9UM47-1.2	K2232P	Neutral	0.153
NOTCH3	Q9UM47-1.2	K2232Q	Neutral	0.009
NOTCH3	Q9UM47-1.2	K2232R	Neutral	0.002
NOTCH3	Q9UM47-1.2	K2232S	Neutral	0.036
NOTCH3	Q9UM47-1.2	K2232T	Neutral	0.154
NOTCH3	Q9UM47-1.2	K2232V	Neutral	0.467
NOTCH3	Q9UM47-1.2	K2232W	Pathogenic	0.802
NOTCH3	Q9UM47-1.2	K2232Y	Neutral	0.49
NOTCH3	Q9UM47-1.2	A2233C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2233D	Neutral	0.055
NOTCH3	Q9UM47-1.2	A2233E	Neutral	0.012
NOTCH3	Q9UM47-1.2	A2233F	Neutral	0.047
NOTCH3	Q9UM47-1.2	A2233G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2233H	Neutral	0.049
NOTCH3	Q9UM47-1.2	A2233I	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2233K	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2233L	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2233M	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2233N	Neutral	0.054
NOTCH3	Q9UM47-1.2	A2233P	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2233Q	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2233R	Neutral	0.01
NOTCH3	Q9UM47-1.2	A2233S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2233T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2233V	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2233W	Neutral	0.167
NOTCH3	Q9UM47-1.2	A2233Y	Neutral	0.045
NOTCH3	Q9UM47-1.2	R2234A	Neutral	0.074
NOTCH3	Q9UM47-1.2	R2234C	Pathogenic	0.643
NOTCH3	Q9UM47-1.2	R2234D	Neutral	0.284
NOTCH3	Q9UM47-1.2	R2234E	Neutral	0.02
NOTCH3	Q9UM47-1.2	R2234F	Pathogenic	0.686
NOTCH3	Q9UM47-1.2	R2234G	Neutral	0.253
NOTCH3	Q9UM47-1.2	R2234H	Neutral	0.021
NOTCH3	Q9UM47-1.2	R2234I	Pathogenic	0.677
NOTCH3	Q9UM47-1.2	R2234K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R2234L	Neutral	0.315
NOTCH3	Q9UM47-1.2	R2234M	Neutral	0.092
NOTCH3	Q9UM47-1.2	R2234N	Neutral	0.019
NOTCH3	Q9UM47-1.2	R2234P	Neutral	0.286
NOTCH3	Q9UM47-1.2	R2234Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	R2234S	Neutral	0.076
NOTCH3	Q9UM47-1.2	R2234T	Neutral	0.082
NOTCH3	Q9UM47-1.2	R2234V	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	R2234W	Pathogenic	0.686
NOTCH3	Q9UM47-1.2	R2234Y	Neutral	0.328
NOTCH3	Q9UM47-1.2	F2235A	Neutral	0.219
NOTCH3	Q9UM47-1.2	F2235C	Neutral	0.231
NOTCH3	Q9UM47-1.2	F2235D	Pathogenic	0.585
NOTCH3	Q9UM47-1.2	F2235E	Pathogenic	0.602
NOTCH3	Q9UM47-1.2	F2235G	Pathogenic	0.543
NOTCH3	Q9UM47-1.2	F2235H	Neutral	0.07
NOTCH3	Q9UM47-1.2	F2235I	Neutral	0.016
NOTCH3	Q9UM47-1.2	F2235K	Pathogenic	0.626
NOTCH3	Q9UM47-1.2	F2235L	Neutral	0.016
NOTCH3	Q9UM47-1.2	F2235M	Neutral	0.016
NOTCH3	Q9UM47-1.2	F2235N	Pathogenic	0.59
NOTCH3	Q9UM47-1.2	F2235P	Pathogenic	0.863
NOTCH3	Q9UM47-1.2	F2235Q	Pathogenic	0.606
NOTCH3	Q9UM47-1.2	F2235R	Pathogenic	0.614
NOTCH3	Q9UM47-1.2	F2235S	Neutral	0.223
NOTCH3	Q9UM47-1.2	F2235T	Neutral	0.237
NOTCH3	Q9UM47-1.2	F2235V	Neutral	0.066
NOTCH3	Q9UM47-1.2	F2235W	Neutral	0.003
NOTCH3	Q9UM47-1.2	F2235Y	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2236A	Neutral	0.103
NOTCH3	Q9UM47-1.2	L2236C	Neutral	0.11
NOTCH3	Q9UM47-1.2	L2236D	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	L2236E	Pathogenic	0.739
NOTCH3	Q9UM47-1.2	L2236F	Neutral	0.029
NOTCH3	Q9UM47-1.2	L2236G	Pathogenic	0.91
NOTCH3	Q9UM47-1.2	L2236H	Pathogenic	0.745
NOTCH3	Q9UM47-1.2	L2236I	Neutral	0.002
NOTCH3	Q9UM47-1.2	L2236K	Neutral	0.388
NOTCH3	Q9UM47-1.2	L2236M	Neutral	0.002
NOTCH3	Q9UM47-1.2	L2236N	Pathogenic	0.729
NOTCH3	Q9UM47-1.2	L2236P	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	L2236Q	Neutral	0.387
NOTCH3	Q9UM47-1.2	L2236R	Neutral	0.376
NOTCH3	Q9UM47-1.2	L2236S	Neutral	0.35
NOTCH3	Q9UM47-1.2	L2236T	Neutral	0.113
NOTCH3	Q9UM47-1.2	L2236V	Neutral	0.006
NOTCH3	Q9UM47-1.2	L2236W	Neutral	0.359
NOTCH3	Q9UM47-1.2	L2236Y	Neutral	0.118
NOTCH3	Q9UM47-1.2	R2237A	Neutral	0.038
NOTCH3	Q9UM47-1.2	R2237C	Neutral	0.467
NOTCH3	Q9UM47-1.2	R2237D	Neutral	0.162
NOTCH3	Q9UM47-1.2	R2237E	Neutral	0.01
NOTCH3	Q9UM47-1.2	R2237F	Pathogenic	0.516
NOTCH3	Q9UM47-1.2	R2237G	Neutral	0.142
NOTCH3	Q9UM47-1.2	R2237H	Neutral	0.01
NOTCH3	Q9UM47-1.2	R2237I	Pathogenic	0.505
NOTCH3	Q9UM47-1.2	R2237K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R2237L	Neutral	0.183
NOTCH3	Q9UM47-1.2	R2237M	Neutral	0.047
NOTCH3	Q9UM47-1.2	R2237N	Neutral	0.009
NOTCH3	Q9UM47-1.2	R2237P	Neutral	0.163
NOTCH3	Q9UM47-1.2	R2237Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	R2237S	Neutral	0.038
NOTCH3	Q9UM47-1.2	R2237T	Neutral	0.041
NOTCH3	Q9UM47-1.2	R2237V	Neutral	0.486
NOTCH3	Q9UM47-1.2	R2237W	Pathogenic	0.515
NOTCH3	Q9UM47-1.2	R2237Y	Neutral	0.192
NOTCH3	Q9UM47-1.2	V2238A	Neutral	0.057
NOTCH3	Q9UM47-1.2	V2238C	Neutral	0.229
NOTCH3	Q9UM47-1.2	V2238D	Pathogenic	0.864
NOTCH3	Q9UM47-1.2	V2238E	Pathogenic	0.592
NOTCH3	Q9UM47-1.2	V2238F	Neutral	0.222
NOTCH3	Q9UM47-1.2	V2238G	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	V2238H	Pathogenic	0.864
NOTCH3	Q9UM47-1.2	V2238I	Neutral	0.001
NOTCH3	Q9UM47-1.2	V2238K	Pathogenic	0.568
NOTCH3	Q9UM47-1.2	V2238L	Neutral	0.014
NOTCH3	Q9UM47-1.2	V2238M	Neutral	0.014
NOTCH3	Q9UM47-1.2	V2238N	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	V2238P	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	V2238Q	Pathogenic	0.586
NOTCH3	Q9UM47-1.2	V2238R	Pathogenic	0.851
NOTCH3	Q9UM47-1.2	V2238S	Pathogenic	0.564
NOTCH3	Q9UM47-1.2	V2238T	Neutral	0.063
NOTCH3	Q9UM47-1.2	V2238W	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	V2238Y	Neutral	0.217
NOTCH3	Q9UM47-1.2	P2239A	Neutral	0.259
NOTCH3	Q9UM47-1.2	P2239C	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	P2239D	Neutral	0.277
NOTCH3	Q9UM47-1.2	P2239E	Neutral	0.263
NOTCH3	Q9UM47-1.2	P2239F	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	P2239G	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	P2239H	Pathogenic	0.609
NOTCH3	Q9UM47-1.2	P2239I	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	P2239K	Neutral	0.245
NOTCH3	Q9UM47-1.2	P2239L	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	P2239M	Pathogenic	0.604
NOTCH3	Q9UM47-1.2	P2239N	Pathogenic	0.631
NOTCH3	Q9UM47-1.2	P2239Q	Neutral	0.259
NOTCH3	Q9UM47-1.2	P2239R	Pathogenic	0.584
NOTCH3	Q9UM47-1.2	P2239S	Neutral	0.264
NOTCH3	Q9UM47-1.2	P2239T	Neutral	0.274
NOTCH3	Q9UM47-1.2	P2239V	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	P2239W	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	P2239Y	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	S2240A	Neutral	0.002
NOTCH3	Q9UM47-1.2	S2240C	Neutral	0.035
NOTCH3	Q9UM47-1.2	S2240D	Neutral	0.008
NOTCH3	Q9UM47-1.2	S2240E	Neutral	0.007
NOTCH3	Q9UM47-1.2	S2240F	Neutral	0.122
NOTCH3	Q9UM47-1.2	S2240G	Neutral	0.008
NOTCH3	Q9UM47-1.2	S2240H	Neutral	0.031
NOTCH3	Q9UM47-1.2	S2240I	Neutral	0.126
NOTCH3	Q9UM47-1.2	S2240K	Neutral	0.007
NOTCH3	Q9UM47-1.2	S2240L	Neutral	0.126
NOTCH3	Q9UM47-1.2	S2240M	Neutral	0.031
NOTCH3	Q9UM47-1.2	S2240N	Neutral	0.002
NOTCH3	Q9UM47-1.2	S2240P	Neutral	0.035
NOTCH3	Q9UM47-1.2	S2240Q	Neutral	0.007
NOTCH3	Q9UM47-1.2	S2240R	Neutral	0.028
NOTCH3	Q9UM47-1.2	S2240T	Neutral	0.002
NOTCH3	Q9UM47-1.2	S2240V	Neutral	0.134
NOTCH3	Q9UM47-1.2	S2240W	Neutral	0.363
NOTCH3	Q9UM47-1.2	S2240Y	Neutral	0.119
NOTCH3	Q9UM47-1.2	E2241A	Neutral	0.287
NOTCH3	Q9UM47-1.2	E2241C	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	E2241D	Neutral	0.005
NOTCH3	Q9UM47-1.2	E2241F	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	E2241G	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	E2241H	Neutral	0.091
NOTCH3	Q9UM47-1.2	E2241I	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	E2241K	Neutral	0.02
NOTCH3	Q9UM47-1.2	E2241L	Pathogenic	0.904
NOTCH3	Q9UM47-1.2	E2241M	Pathogenic	0.672
NOTCH3	Q9UM47-1.2	E2241N	Neutral	0.09
NOTCH3	Q9UM47-1.2	E2241P	Neutral	0.307
NOTCH3	Q9UM47-1.2	E2241Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	E2241R	Neutral	0.082
NOTCH3	Q9UM47-1.2	E2241S	Neutral	0.083
NOTCH3	Q9UM47-1.2	E2241T	Neutral	0.308
NOTCH3	Q9UM47-1.2	E2241V	Pathogenic	0.682
NOTCH3	Q9UM47-1.2	E2241W	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	E2241Y	Pathogenic	0.657
NOTCH3	Q9UM47-1.2	H2242A	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	H2242C	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	H2242D	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	H2242E	Pathogenic	0.536
NOTCH3	Q9UM47-1.2	H2242F	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	H2242G	Pathogenic	0.95
NOTCH3	Q9UM47-1.2	H2242I	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	H2242K	Pathogenic	0.837
NOTCH3	Q9UM47-1.2	H2242L	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	H2242M	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	H2242N	Neutral	0.195
NOTCH3	Q9UM47-1.2	H2242P	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	H2242Q	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	H2242R	Pathogenic	0.517
NOTCH3	Q9UM47-1.2	H2242S	Pathogenic	0.82
NOTCH3	Q9UM47-1.2	H2242T	Pathogenic	0.957
NOTCH3	Q9UM47-1.2	H2242V	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	H2242W	Pathogenic	0.955
NOTCH3	Q9UM47-1.2	H2242Y	Neutral	0.05
NOTCH3	Q9UM47-1.2	P2243A	Pathogenic	0.521
NOTCH3	Q9UM47-1.2	P2243C	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	P2243D	Pathogenic	0.544
NOTCH3	Q9UM47-1.2	P2243E	Pathogenic	0.526
NOTCH3	Q9UM47-1.2	P2243F	Pathogenic	0.99
NOTCH3	Q9UM47-1.2	P2243G	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	P2243H	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	P2243I	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	P2243K	Pathogenic	0.502
NOTCH3	Q9UM47-1.2	P2243L	Pathogenic	0.956
NOTCH3	Q9UM47-1.2	P2243M	Pathogenic	0.826
NOTCH3	Q9UM47-1.2	P2243N	Pathogenic	0.842
NOTCH3	Q9UM47-1.2	P2243Q	Pathogenic	0.521
NOTCH3	Q9UM47-1.2	P2243R	Pathogenic	0.814
NOTCH3	Q9UM47-1.2	P2243S	Pathogenic	0.527
NOTCH3	Q9UM47-1.2	P2243T	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	P2243V	Pathogenic	0.836
NOTCH3	Q9UM47-1.2	P2243W	Pathogenic	0.988
NOTCH3	Q9UM47-1.2	P2243Y	Pathogenic	0.953
NOTCH3	Q9UM47-1.2	Y2244A	Pathogenic	0.897
NOTCH3	Q9UM47-1.2	Y2244C	Pathogenic	0.903
NOTCH3	Q9UM47-1.2	Y2244D	Pathogenic	0.978
NOTCH3	Q9UM47-1.2	Y2244E	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	Y2244F	Neutral	0.006
NOTCH3	Q9UM47-1.2	Y2244G	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	Y2244H	Neutral	0.024
NOTCH3	Q9UM47-1.2	Y2244I	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	Y2244K	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	Y2244L	Pathogenic	0.704
NOTCH3	Q9UM47-1.2	Y2244M	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	Y2244N	Pathogenic	0.907
NOTCH3	Q9UM47-1.2	Y2244P	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	Y2244Q	Pathogenic	0.697
NOTCH3	Q9UM47-1.2	Y2244R	Pathogenic	0.919
NOTCH3	Q9UM47-1.2	Y2244S	Pathogenic	0.899
NOTCH3	Q9UM47-1.2	Y2244T	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	Y2244V	Pathogenic	0.688
NOTCH3	Q9UM47-1.2	Y2244W	Neutral	0.024
NOTCH3	Q9UM47-1.2	L2245A	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	L2245C	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	L2245D	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	L2245E	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	L2245F	Neutral	0.243
NOTCH3	Q9UM47-1.2	L2245G	Pathogenic	0.991
NOTCH3	Q9UM47-1.2	L2245H	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	L2245I	Neutral	0.016
NOTCH3	Q9UM47-1.2	L2245K	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	L2245M	Neutral	0.016
NOTCH3	Q9UM47-1.2	L2245N	Pathogenic	0.967
NOTCH3	Q9UM47-1.2	L2245P	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	L2245Q	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	L2245R	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	L2245S	Pathogenic	0.853
NOTCH3	Q9UM47-1.2	L2245T	Pathogenic	0.578
NOTCH3	Q9UM47-1.2	L2245V	Neutral	0.064
NOTCH3	Q9UM47-1.2	L2245W	Pathogenic	0.857
NOTCH3	Q9UM47-1.2	L2245Y	Pathogenic	0.59
NOTCH3	Q9UM47-1.2	T2246A	Neutral	0.376
NOTCH3	Q9UM47-1.2	T2246C	Pathogenic	0.748
NOTCH3	Q9UM47-1.2	T2246D	Pathogenic	0.752
NOTCH3	Q9UM47-1.2	T2246E	Pathogenic	0.742
NOTCH3	Q9UM47-1.2	T2246F	Pathogenic	0.923
NOTCH3	Q9UM47-1.2	T2246G	Pathogenic	0.921
NOTCH3	Q9UM47-1.2	T2246H	Pathogenic	0.926
NOTCH3	Q9UM47-1.2	T2246I	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	T2246K	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	T2246L	Pathogenic	0.732
NOTCH3	Q9UM47-1.2	T2246M	Pathogenic	0.731
NOTCH3	Q9UM47-1.2	T2246N	Neutral	0.399
NOTCH3	Q9UM47-1.2	T2246P	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	T2246Q	Pathogenic	0.738
NOTCH3	Q9UM47-1.2	T2246R	Pathogenic	0.713
NOTCH3	Q9UM47-1.2	T2246S	Neutral	0.12
NOTCH3	Q9UM47-1.2	T2246V	Neutral	0.391
NOTCH3	Q9UM47-1.2	T2246W	Pathogenic	0.915
NOTCH3	Q9UM47-1.2	T2246Y	Pathogenic	0.92
NOTCH3	Q9UM47-1.2	P2247A	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	P2247C	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	P2247D	Pathogenic	0.649
NOTCH3	Q9UM47-1.2	P2247E	Pathogenic	0.633
NOTCH3	Q9UM47-1.2	P2247F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	P2247G	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	P2247H	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	P2247I	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	P2247K	Pathogenic	0.61
NOTCH3	Q9UM47-1.2	P2247L	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	P2247M	Pathogenic	0.88
NOTCH3	Q9UM47-1.2	P2247N	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	P2247Q	Pathogenic	0.627
NOTCH3	Q9UM47-1.2	P2247R	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	P2247S	Pathogenic	0.633
NOTCH3	Q9UM47-1.2	P2247T	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	P2247V	Pathogenic	0.888
NOTCH3	Q9UM47-1.2	P2247W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	P2247Y	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	S2248A	Neutral	0.083
NOTCH3	Q9UM47-1.2	S2248C	Pathogenic	0.648
NOTCH3	Q9UM47-1.2	S2248D	Neutral	0.283
NOTCH3	Q9UM47-1.2	S2248E	Neutral	0.269
NOTCH3	Q9UM47-1.2	S2248F	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	S2248G	Neutral	0.277
NOTCH3	Q9UM47-1.2	S2248H	Pathogenic	0.618
NOTCH3	Q9UM47-1.2	S2248I	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	S2248K	Neutral	0.251
NOTCH3	Q9UM47-1.2	S2248L	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	S2248M	Pathogenic	0.614
NOTCH3	Q9UM47-1.2	S2248N	Neutral	0.078
NOTCH3	Q9UM47-1.2	S2248P	Pathogenic	0.644
NOTCH3	Q9UM47-1.2	S2248Q	Neutral	0.265
NOTCH3	Q9UM47-1.2	S2248R	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	S2248T	Neutral	0.079
NOTCH3	Q9UM47-1.2	S2248V	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	S2248W	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	S2248Y	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	P2249A	Pathogenic	0.624
NOTCH3	Q9UM47-1.2	P2249C	Pathogenic	0.974
NOTCH3	Q9UM47-1.2	P2249D	Pathogenic	0.645
NOTCH3	Q9UM47-1.2	P2249E	Pathogenic	0.629
NOTCH3	Q9UM47-1.2	P2249F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	P2249G	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	P2249H	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	P2249I	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	P2249K	Pathogenic	0.606
NOTCH3	Q9UM47-1.2	P2249L	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	P2249M	Pathogenic	0.879
NOTCH3	Q9UM47-1.2	P2249N	Pathogenic	0.89
NOTCH3	Q9UM47-1.2	P2249Q	Pathogenic	0.624
NOTCH3	Q9UM47-1.2	P2249R	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	P2249S	Pathogenic	0.63
NOTCH3	Q9UM47-1.2	P2249T	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	P2249V	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	P2249W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	P2249Y	Pathogenic	0.969
NOTCH3	Q9UM47-1.2	E2250A	Pathogenic	0.535
NOTCH3	Q9UM47-1.2	E2250C	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	E2250D	Neutral	0.013
NOTCH3	Q9UM47-1.2	E2250F	Pathogenic	0.962
NOTCH3	Q9UM47-1.2	E2250G	Pathogenic	0.829
NOTCH3	Q9UM47-1.2	E2250H	Neutral	0.223
NOTCH3	Q9UM47-1.2	E2250I	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	E2250K	Neutral	0.055
NOTCH3	Q9UM47-1.2	E2250L	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	E2250M	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	E2250N	Neutral	0.219
NOTCH3	Q9UM47-1.2	E2250P	Pathogenic	0.558
NOTCH3	Q9UM47-1.2	E2250Q	Neutral	0.014
NOTCH3	Q9UM47-1.2	E2250R	Neutral	0.203
NOTCH3	Q9UM47-1.2	E2250S	Neutral	0.205
NOTCH3	Q9UM47-1.2	E2250T	Pathogenic	0.559
NOTCH3	Q9UM47-1.2	E2250V	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	E2250W	Pathogenic	0.959
NOTCH3	Q9UM47-1.2	E2250Y	Pathogenic	0.845
NOTCH3	Q9UM47-1.2	S2251A	Neutral	0.079
NOTCH3	Q9UM47-1.2	S2251C	Pathogenic	0.636
NOTCH3	Q9UM47-1.2	S2251D	Neutral	0.273
NOTCH3	Q9UM47-1.2	S2251E	Neutral	0.26
NOTCH3	Q9UM47-1.2	S2251F	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	S2251G	Neutral	0.267
NOTCH3	Q9UM47-1.2	S2251H	Pathogenic	0.606
NOTCH3	Q9UM47-1.2	S2251I	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	S2251K	Neutral	0.241
NOTCH3	Q9UM47-1.2	S2251L	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	S2251M	Pathogenic	0.602
NOTCH3	Q9UM47-1.2	S2251N	Neutral	0.075
NOTCH3	Q9UM47-1.2	S2251P	Pathogenic	0.632
NOTCH3	Q9UM47-1.2	S2251Q	Neutral	0.255
NOTCH3	Q9UM47-1.2	S2251R	Pathogenic	0.579
NOTCH3	Q9UM47-1.2	S2251T	Neutral	0.076
NOTCH3	Q9UM47-1.2	S2251V	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	S2251W	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	S2251Y	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	P2252A	Pathogenic	0.603
NOTCH3	Q9UM47-1.2	P2252C	Pathogenic	0.971
NOTCH3	Q9UM47-1.2	P2252D	Pathogenic	0.625
NOTCH3	Q9UM47-1.2	P2252E	Pathogenic	0.608
NOTCH3	Q9UM47-1.2	P2252F	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	P2252G	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	P2252H	Pathogenic	0.871
NOTCH3	Q9UM47-1.2	P2252I	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	P2252K	Pathogenic	0.585
NOTCH3	Q9UM47-1.2	P2252L	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	P2252M	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	P2252N	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	P2252Q	Pathogenic	0.603
NOTCH3	Q9UM47-1.2	P2252R	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	P2252S	Pathogenic	0.609
NOTCH3	Q9UM47-1.2	P2252T	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	P2252V	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	P2252W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	P2252Y	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	E2253A	Neutral	0.076
NOTCH3	Q9UM47-1.2	E2253C	Pathogenic	0.894
NOTCH3	Q9UM47-1.2	E2253D	Neutral	0.001
NOTCH3	Q9UM47-1.2	E2253F	Pathogenic	0.649
NOTCH3	Q9UM47-1.2	E2253G	Neutral	0.259
NOTCH3	Q9UM47-1.2	E2253H	Neutral	0.02
NOTCH3	Q9UM47-1.2	E2253I	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	E2253K	Neutral	0.004
NOTCH3	Q9UM47-1.2	E2253L	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	E2253M	Neutral	0.296
NOTCH3	Q9UM47-1.2	E2253N	Neutral	0.02
NOTCH3	Q9UM47-1.2	E2253P	Neutral	0.083
NOTCH3	Q9UM47-1.2	E2253Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	E2253R	Neutral	0.018
NOTCH3	Q9UM47-1.2	E2253S	Neutral	0.018
NOTCH3	Q9UM47-1.2	E2253T	Neutral	0.084
NOTCH3	Q9UM47-1.2	E2253V	Neutral	0.305
NOTCH3	Q9UM47-1.2	E2253W	Pathogenic	0.625
NOTCH3	Q9UM47-1.2	E2253Y	Neutral	0.282
NOTCH3	Q9UM47-1.2	H2254A	Neutral	0.461
NOTCH3	Q9UM47-1.2	H2254C	Pathogenic	0.808
NOTCH3	Q9UM47-1.2	H2254D	Neutral	0.172
NOTCH3	Q9UM47-1.2	H2254E	Neutral	0.046
NOTCH3	Q9UM47-1.2	H2254F	Neutral	0.178
NOTCH3	Q9UM47-1.2	H2254G	Neutral	0.442
NOTCH3	Q9UM47-1.2	H2254I	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	H2254K	Neutral	0.177
NOTCH3	Q9UM47-1.2	H2254L	Pathogenic	0.824
NOTCH3	Q9UM47-1.2	H2254M	Pathogenic	0.506
NOTCH3	Q9UM47-1.2	H2254N	Neutral	0.01
NOTCH3	Q9UM47-1.2	H2254P	Neutral	0.484
NOTCH3	Q9UM47-1.2	H2254Q	Neutral	0.047
NOTCH3	Q9UM47-1.2	H2254R	Neutral	0.043
NOTCH3	Q9UM47-1.2	H2254S	Neutral	0.161
NOTCH3	Q9UM47-1.2	H2254T	Neutral	0.485
NOTCH3	Q9UM47-1.2	H2254V	Pathogenic	0.819
NOTCH3	Q9UM47-1.2	H2254W	Neutral	0.47
NOTCH3	Q9UM47-1.2	H2254Y	Neutral	0.002
NOTCH3	Q9UM47-1.2	W2255A	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W2255C	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W2255D	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W2255E	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W2255F	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	W2255G	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W2255H	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W2255I	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W2255K	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W2255L	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W2255M	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	W2255N	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W2255P	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W2255Q	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W2255R	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W2255S	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W2255T	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W2255V	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W2255Y	Pathogenic	0.511
NOTCH3	Q9UM47-1.2	A2256C	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2256D	Neutral	0.182
NOTCH3	Q9UM47-1.2	A2256E	Neutral	0.044
NOTCH3	Q9UM47-1.2	A2256F	Neutral	0.159
NOTCH3	Q9UM47-1.2	A2256G	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2256H	Neutral	0.166
NOTCH3	Q9UM47-1.2	A2256I	Neutral	0.041
NOTCH3	Q9UM47-1.2	A2256K	Neutral	0.04
NOTCH3	Q9UM47-1.2	A2256L	Neutral	0.041
NOTCH3	Q9UM47-1.2	A2256M	Neutral	0.041
NOTCH3	Q9UM47-1.2	A2256N	Neutral	0.179
NOTCH3	Q9UM47-1.2	A2256P	Neutral	0.047
NOTCH3	Q9UM47-1.2	A2256Q	Neutral	0.043
NOTCH3	Q9UM47-1.2	A2256R	Neutral	0.038
NOTCH3	Q9UM47-1.2	A2256S	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2256T	Neutral	0.01
NOTCH3	Q9UM47-1.2	A2256V	Neutral	0.01
NOTCH3	Q9UM47-1.2	A2256W	Neutral	0.436
NOTCH3	Q9UM47-1.2	A2256Y	Neutral	0.155
NOTCH3	Q9UM47-1.2	S2257A	Neutral	0.077
NOTCH3	Q9UM47-1.2	S2257C	Pathogenic	0.629
NOTCH3	Q9UM47-1.2	S2257D	Neutral	0.267
NOTCH3	Q9UM47-1.2	S2257E	Neutral	0.254
NOTCH3	Q9UM47-1.2	S2257F	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	S2257G	Neutral	0.261
NOTCH3	Q9UM47-1.2	S2257H	Pathogenic	0.598
NOTCH3	Q9UM47-1.2	S2257I	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	S2257K	Neutral	0.236
NOTCH3	Q9UM47-1.2	S2257L	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	S2257M	Pathogenic	0.595
NOTCH3	Q9UM47-1.2	S2257N	Neutral	0.073
NOTCH3	Q9UM47-1.2	S2257P	Pathogenic	0.625
NOTCH3	Q9UM47-1.2	S2257Q	Neutral	0.249
NOTCH3	Q9UM47-1.2	S2257R	Pathogenic	0.572
NOTCH3	Q9UM47-1.2	S2257T	Neutral	0.073
NOTCH3	Q9UM47-1.2	S2257V	Pathogenic	0.878
NOTCH3	Q9UM47-1.2	S2257W	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	S2257Y	Pathogenic	0.862
NOTCH3	Q9UM47-1.2	P2258A	Neutral	0.058
NOTCH3	Q9UM47-1.2	P2258C	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	P2258D	Neutral	0.064
NOTCH3	Q9UM47-1.2	P2258E	Neutral	0.06
NOTCH3	Q9UM47-1.2	P2258F	Pathogenic	0.844
NOTCH3	Q9UM47-1.2	P2258G	Neutral	0.208
NOTCH3	Q9UM47-1.2	P2258H	Neutral	0.217
NOTCH3	Q9UM47-1.2	P2258I	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	P2258K	Neutral	0.054
NOTCH3	Q9UM47-1.2	P2258L	Pathogenic	0.553
NOTCH3	Q9UM47-1.2	P2258M	Neutral	0.213
NOTCH3	Q9UM47-1.2	P2258N	Neutral	0.233
NOTCH3	Q9UM47-1.2	P2258Q	Neutral	0.058
NOTCH3	Q9UM47-1.2	P2258R	Neutral	0.2
NOTCH3	Q9UM47-1.2	P2258S	Neutral	0.06
NOTCH3	Q9UM47-1.2	P2258T	Neutral	0.063
NOTCH3	Q9UM47-1.2	P2258V	Neutral	0.226
NOTCH3	Q9UM47-1.2	P2258W	Pathogenic	0.83
NOTCH3	Q9UM47-1.2	P2258Y	Pathogenic	0.535
NOTCH3	Q9UM47-1.2	S2259A	Neutral	0.082
NOTCH3	Q9UM47-1.2	S2259C	Pathogenic	0.646
NOTCH3	Q9UM47-1.2	S2259D	Neutral	0.282
NOTCH3	Q9UM47-1.2	S2259E	Neutral	0.267
NOTCH3	Q9UM47-1.2	S2259F	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	S2259G	Neutral	0.275
NOTCH3	Q9UM47-1.2	S2259H	Pathogenic	0.615
NOTCH3	Q9UM47-1.2	S2259I	Pathogenic	0.878
NOTCH3	Q9UM47-1.2	S2259K	Neutral	0.249
NOTCH3	Q9UM47-1.2	S2259L	Pathogenic	0.878
NOTCH3	Q9UM47-1.2	S2259M	Pathogenic	0.612
NOTCH3	Q9UM47-1.2	S2259N	Neutral	0.078
NOTCH3	Q9UM47-1.2	S2259P	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	S2259Q	Neutral	0.263
NOTCH3	Q9UM47-1.2	S2259R	Pathogenic	0.589
NOTCH3	Q9UM47-1.2	S2259T	Neutral	0.078
NOTCH3	Q9UM47-1.2	S2259V	Pathogenic	0.885
NOTCH3	Q9UM47-1.2	S2259W	Pathogenic	0.966
NOTCH3	Q9UM47-1.2	S2259Y	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	P2260A	Pathogenic	0.636
NOTCH3	Q9UM47-1.2	P2260C	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	P2260D	Pathogenic	0.658
NOTCH3	Q9UM47-1.2	P2260E	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	P2260F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	P2260G	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	P2260H	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	P2260I	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	P2260K	Pathogenic	0.619
NOTCH3	Q9UM47-1.2	P2260L	Pathogenic	0.972
NOTCH3	Q9UM47-1.2	P2260M	Pathogenic	0.884
NOTCH3	Q9UM47-1.2	P2260N	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	P2260Q	Pathogenic	0.637
NOTCH3	Q9UM47-1.2	P2260R	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	P2260S	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	P2260T	Pathogenic	0.654
NOTCH3	Q9UM47-1.2	P2260V	Pathogenic	0.892
NOTCH3	Q9UM47-1.2	P2260W	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	P2260Y	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	P2261A	Neutral	0.023
NOTCH3	Q9UM47-1.2	P2261C	Neutral	0.348
NOTCH3	Q9UM47-1.2	P2261D	Neutral	0.026
NOTCH3	Q9UM47-1.2	P2261E	Neutral	0.024
NOTCH3	Q9UM47-1.2	P2261F	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	P2261G	Neutral	0.092
NOTCH3	Q9UM47-1.2	P2261H	Neutral	0.097
NOTCH3	Q9UM47-1.2	P2261I	Neutral	0.323
NOTCH3	Q9UM47-1.2	P2261K	Neutral	0.022
NOTCH3	Q9UM47-1.2	P2261L	Neutral	0.323
NOTCH3	Q9UM47-1.2	P2261M	Neutral	0.095
NOTCH3	Q9UM47-1.2	P2261N	Neutral	0.105
NOTCH3	Q9UM47-1.2	P2261Q	Neutral	0.023
NOTCH3	Q9UM47-1.2	P2261R	Neutral	0.088
NOTCH3	Q9UM47-1.2	P2261S	Neutral	0.024
NOTCH3	Q9UM47-1.2	P2261T	Neutral	0.025
NOTCH3	Q9UM47-1.2	P2261V	Neutral	0.101
NOTCH3	Q9UM47-1.2	P2261W	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	P2261Y	Neutral	0.308
NOTCH3	Q9UM47-1.2	S2262A	Neutral	0.054
NOTCH3	Q9UM47-1.2	S2262C	Pathogenic	0.538
NOTCH3	Q9UM47-1.2	S2262D	Neutral	0.2
NOTCH3	Q9UM47-1.2	S2262E	Neutral	0.189
NOTCH3	Q9UM47-1.2	S2262F	Pathogenic	0.815
NOTCH3	Q9UM47-1.2	S2262G	Neutral	0.195
NOTCH3	Q9UM47-1.2	S2262H	Pathogenic	0.505
NOTCH3	Q9UM47-1.2	S2262I	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	S2262K	Neutral	0.175
NOTCH3	Q9UM47-1.2	S2262L	Pathogenic	0.822
NOTCH3	Q9UM47-1.2	S2262M	Pathogenic	0.502
NOTCH3	Q9UM47-1.2	S2262N	Neutral	0.051
NOTCH3	Q9UM47-1.2	S2262P	Pathogenic	0.534
NOTCH3	Q9UM47-1.2	S2262Q	Neutral	0.186
NOTCH3	Q9UM47-1.2	S2262R	Neutral	0.478
NOTCH3	Q9UM47-1.2	S2262T	Neutral	0.052
NOTCH3	Q9UM47-1.2	S2262V	Pathogenic	0.831
NOTCH3	Q9UM47-1.2	S2262W	Pathogenic	0.948
NOTCH3	Q9UM47-1.2	S2262Y	Pathogenic	0.811
NOTCH3	Q9UM47-1.2	L2263A	Neutral	0.012
NOTCH3	Q9UM47-1.2	L2263C	Neutral	0.013
NOTCH3	Q9UM47-1.2	L2263D	Pathogenic	0.559
NOTCH3	Q9UM47-1.2	L2263E	Neutral	0.23
NOTCH3	Q9UM47-1.2	L2263F	Neutral	0.003
NOTCH3	Q9UM47-1.2	L2263G	Pathogenic	0.517
NOTCH3	Q9UM47-1.2	L2263H	Neutral	0.235
NOTCH3	Q9UM47-1.2	L2263I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2263K	Neutral	0.063
NOTCH3	Q9UM47-1.2	L2263M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2263N	Neutral	0.221
NOTCH3	Q9UM47-1.2	L2263P	Neutral	0.215
NOTCH3	Q9UM47-1.2	L2263Q	Neutral	0.062
NOTCH3	Q9UM47-1.2	L2263R	Neutral	0.06
NOTCH3	Q9UM47-1.2	L2263S	Neutral	0.054
NOTCH3	Q9UM47-1.2	L2263T	Neutral	0.013
NOTCH3	Q9UM47-1.2	L2263V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2263W	Neutral	0.056
NOTCH3	Q9UM47-1.2	L2263Y	Neutral	0.014
NOTCH3	Q9UM47-1.2	S2264A	Neutral	0.08
NOTCH3	Q9UM47-1.2	S2264C	Pathogenic	0.637
NOTCH3	Q9UM47-1.2	S2264D	Neutral	0.274
NOTCH3	Q9UM47-1.2	S2264E	Neutral	0.26
NOTCH3	Q9UM47-1.2	S2264F	Pathogenic	0.869
NOTCH3	Q9UM47-1.2	S2264G	Neutral	0.267
NOTCH3	Q9UM47-1.2	S2264H	Pathogenic	0.606
NOTCH3	Q9UM47-1.2	S2264I	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	S2264K	Neutral	0.242
NOTCH3	Q9UM47-1.2	S2264L	Pathogenic	0.874
NOTCH3	Q9UM47-1.2	S2264M	Pathogenic	0.603
NOTCH3	Q9UM47-1.2	S2264N	Neutral	0.075
NOTCH3	Q9UM47-1.2	S2264P	Pathogenic	0.633
NOTCH3	Q9UM47-1.2	S2264Q	Neutral	0.256
NOTCH3	Q9UM47-1.2	S2264R	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	S2264T	Neutral	0.076
NOTCH3	Q9UM47-1.2	S2264V	Pathogenic	0.881
NOTCH3	Q9UM47-1.2	S2264W	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	S2264Y	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	D2265A	Pathogenic	0.906
NOTCH3	Q9UM47-1.2	D2265C	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	D2265E	Neutral	0.022
NOTCH3	Q9UM47-1.2	D2265F	Pathogenic	0.976
NOTCH3	Q9UM47-1.2	D2265G	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	D2265H	Pathogenic	0.675
NOTCH3	Q9UM47-1.2	D2265I	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	D2265K	Pathogenic	0.66
NOTCH3	Q9UM47-1.2	D2265L	Pathogenic	0.995
NOTCH3	Q9UM47-1.2	D2265M	Pathogenic	0.977
NOTCH3	Q9UM47-1.2	D2265N	Neutral	0.098
NOTCH3	Q9UM47-1.2	D2265P	Pathogenic	0.698
NOTCH3	Q9UM47-1.2	D2265Q	Neutral	0.316
NOTCH3	Q9UM47-1.2	D2265R	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	D2265S	Neutral	0.321
NOTCH3	Q9UM47-1.2	D2265T	Pathogenic	0.696
NOTCH3	Q9UM47-1.2	D2265V	Pathogenic	0.979
NOTCH3	Q9UM47-1.2	D2265W	Pathogenic	0.994
NOTCH3	Q9UM47-1.2	D2265Y	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	W2266A	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W2266C	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W2266D	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W2266E	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W2266F	Pathogenic	0.817
NOTCH3	Q9UM47-1.2	W2266G	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W2266H	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W2266I	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W2266K	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W2266L	Pathogenic	0.998
NOTCH3	Q9UM47-1.2	W2266M	Pathogenic	0.989
NOTCH3	Q9UM47-1.2	W2266N	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W2266P	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W2266Q	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W2266R	Pathogenic	1.0
NOTCH3	Q9UM47-1.2	W2266S	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W2266T	Pathogenic	0.997
NOTCH3	Q9UM47-1.2	W2266V	Pathogenic	0.999
NOTCH3	Q9UM47-1.2	W2266Y	Pathogenic	0.503
NOTCH3	Q9UM47-1.2	S2267A	Neutral	0.081
NOTCH3	Q9UM47-1.2	S2267C	Pathogenic	0.641
NOTCH3	Q9UM47-1.2	S2267D	Neutral	0.278
NOTCH3	Q9UM47-1.2	S2267E	Neutral	0.264
NOTCH3	Q9UM47-1.2	S2267F	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	S2267G	Neutral	0.271
NOTCH3	Q9UM47-1.2	S2267H	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	S2267I	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	S2267K	Neutral	0.245
NOTCH3	Q9UM47-1.2	S2267L	Pathogenic	0.876
NOTCH3	Q9UM47-1.2	S2267M	Pathogenic	0.608
NOTCH3	Q9UM47-1.2	S2267N	Neutral	0.076
NOTCH3	Q9UM47-1.2	S2267P	Pathogenic	0.637
NOTCH3	Q9UM47-1.2	S2267Q	Neutral	0.259
NOTCH3	Q9UM47-1.2	S2267R	Pathogenic	0.585
NOTCH3	Q9UM47-1.2	S2267T	Neutral	0.077
NOTCH3	Q9UM47-1.2	S2267V	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	S2267W	Pathogenic	0.965
NOTCH3	Q9UM47-1.2	S2267Y	Pathogenic	0.868
NOTCH3	Q9UM47-1.2	E2268A	Neutral	0.279
NOTCH3	Q9UM47-1.2	E2268C	Pathogenic	0.975
NOTCH3	Q9UM47-1.2	E2268D	Neutral	0.004
NOTCH3	Q9UM47-1.2	E2268F	Pathogenic	0.896
NOTCH3	Q9UM47-1.2	E2268G	Pathogenic	0.62
NOTCH3	Q9UM47-1.2	E2268H	Neutral	0.088
NOTCH3	Q9UM47-1.2	E2268I	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	E2268K	Neutral	0.019
NOTCH3	Q9UM47-1.2	E2268L	Pathogenic	0.9
NOTCH3	Q9UM47-1.2	E2268M	Pathogenic	0.663
NOTCH3	Q9UM47-1.2	E2268N	Neutral	0.086
NOTCH3	Q9UM47-1.2	E2268P	Neutral	0.298
NOTCH3	Q9UM47-1.2	E2268Q	Neutral	0.005
NOTCH3	Q9UM47-1.2	E2268R	Neutral	0.079
NOTCH3	Q9UM47-1.2	E2268S	Neutral	0.08
NOTCH3	Q9UM47-1.2	E2268T	Neutral	0.3
NOTCH3	Q9UM47-1.2	E2268V	Pathogenic	0.673
NOTCH3	Q9UM47-1.2	E2268W	Pathogenic	0.886
NOTCH3	Q9UM47-1.2	E2268Y	Pathogenic	0.648
NOTCH3	Q9UM47-1.2	S2269A	Neutral	0.002
NOTCH3	Q9UM47-1.2	S2269C	Neutral	0.03
NOTCH3	Q9UM47-1.2	S2269D	Neutral	0.007
NOTCH3	Q9UM47-1.2	S2269E	Neutral	0.006
NOTCH3	Q9UM47-1.2	S2269F	Neutral	0.105
NOTCH3	Q9UM47-1.2	S2269G	Neutral	0.006
NOTCH3	Q9UM47-1.2	S2269H	Neutral	0.026
NOTCH3	Q9UM47-1.2	S2269I	Neutral	0.109
NOTCH3	Q9UM47-1.2	S2269K	Neutral	0.006
NOTCH3	Q9UM47-1.2	S2269L	Neutral	0.109
NOTCH3	Q9UM47-1.2	S2269M	Neutral	0.026
NOTCH3	Q9UM47-1.2	S2269N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2269P	Neutral	0.029
NOTCH3	Q9UM47-1.2	S2269Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	S2269R	Neutral	0.024
NOTCH3	Q9UM47-1.2	S2269T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2269V	Neutral	0.116
NOTCH3	Q9UM47-1.2	S2269W	Neutral	0.324
NOTCH3	Q9UM47-1.2	S2269Y	Neutral	0.102
NOTCH3	Q9UM47-1.2	T2270A	Neutral	0.041
NOTCH3	Q9UM47-1.2	T2270C	Neutral	0.172
NOTCH3	Q9UM47-1.2	T2270D	Neutral	0.176
NOTCH3	Q9UM47-1.2	T2270E	Neutral	0.168
NOTCH3	Q9UM47-1.2	T2270F	Neutral	0.455
NOTCH3	Q9UM47-1.2	T2270G	Neutral	0.449
NOTCH3	Q9UM47-1.2	T2270H	Neutral	0.468
NOTCH3	Q9UM47-1.2	T2270I	Neutral	0.161
NOTCH3	Q9UM47-1.2	T2270K	Neutral	0.155
NOTCH3	Q9UM47-1.2	T2270L	Neutral	0.16
NOTCH3	Q9UM47-1.2	T2270M	Neutral	0.16
NOTCH3	Q9UM47-1.2	T2270N	Neutral	0.044
NOTCH3	Q9UM47-1.2	T2270P	Neutral	0.174
NOTCH3	Q9UM47-1.2	T2270Q	Neutral	0.165
NOTCH3	Q9UM47-1.2	T2270R	Neutral	0.148
NOTCH3	Q9UM47-1.2	T2270S	Neutral	0.009
NOTCH3	Q9UM47-1.2	T2270V	Neutral	0.043
NOTCH3	Q9UM47-1.2	T2270W	Neutral	0.429
NOTCH3	Q9UM47-1.2	T2270Y	Neutral	0.447
NOTCH3	Q9UM47-1.2	P2271A	Neutral	0.024
NOTCH3	Q9UM47-1.2	P2271C	Neutral	0.358
NOTCH3	Q9UM47-1.2	P2271D	Neutral	0.027
NOTCH3	Q9UM47-1.2	P2271E	Neutral	0.025
NOTCH3	Q9UM47-1.2	P2271F	Pathogenic	0.686
NOTCH3	Q9UM47-1.2	P2271G	Neutral	0.096
NOTCH3	Q9UM47-1.2	P2271H	Neutral	0.101
NOTCH3	Q9UM47-1.2	P2271I	Neutral	0.333
NOTCH3	Q9UM47-1.2	P2271K	Neutral	0.023
NOTCH3	Q9UM47-1.2	P2271L	Neutral	0.333
NOTCH3	Q9UM47-1.2	P2271M	Neutral	0.099
NOTCH3	Q9UM47-1.2	P2271N	Neutral	0.109
NOTCH3	Q9UM47-1.2	P2271Q	Neutral	0.024
NOTCH3	Q9UM47-1.2	P2271R	Neutral	0.091
NOTCH3	Q9UM47-1.2	P2271S	Neutral	0.025
NOTCH3	Q9UM47-1.2	P2271T	Neutral	0.026
NOTCH3	Q9UM47-1.2	P2271V	Neutral	0.105
NOTCH3	Q9UM47-1.2	P2271W	Pathogenic	0.663
NOTCH3	Q9UM47-1.2	P2271Y	Neutral	0.317
NOTCH3	Q9UM47-1.2	S2272A	Neutral	0.077
NOTCH3	Q9UM47-1.2	S2272C	Pathogenic	0.628
NOTCH3	Q9UM47-1.2	S2272D	Neutral	0.266
NOTCH3	Q9UM47-1.2	S2272E	Neutral	0.253
NOTCH3	Q9UM47-1.2	S2272F	Pathogenic	0.865
NOTCH3	Q9UM47-1.2	S2272G	Neutral	0.26
NOTCH3	Q9UM47-1.2	S2272H	Pathogenic	0.597
NOTCH3	Q9UM47-1.2	S2272I	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	S2272K	Neutral	0.235
NOTCH3	Q9UM47-1.2	S2272L	Pathogenic	0.87
NOTCH3	Q9UM47-1.2	S2272M	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	S2272N	Neutral	0.072
NOTCH3	Q9UM47-1.2	S2272P	Pathogenic	0.624
NOTCH3	Q9UM47-1.2	S2272Q	Neutral	0.248
NOTCH3	Q9UM47-1.2	S2272R	Pathogenic	0.57
NOTCH3	Q9UM47-1.2	S2272T	Neutral	0.073
NOTCH3	Q9UM47-1.2	S2272V	Pathogenic	0.877
NOTCH3	Q9UM47-1.2	S2272W	Pathogenic	0.963
NOTCH3	Q9UM47-1.2	S2272Y	Pathogenic	0.861
NOTCH3	Q9UM47-1.2	P2273A	Pathogenic	0.617
NOTCH3	Q9UM47-1.2	P2273C	Pathogenic	0.973
NOTCH3	Q9UM47-1.2	P2273D	Pathogenic	0.639
NOTCH3	Q9UM47-1.2	P2273E	Pathogenic	0.622
NOTCH3	Q9UM47-1.2	P2273F	Pathogenic	0.993
NOTCH3	Q9UM47-1.2	P2273G	Pathogenic	0.872
NOTCH3	Q9UM47-1.2	P2273H	Pathogenic	0.878
NOTCH3	Q9UM47-1.2	P2273I	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	P2273K	Pathogenic	0.599
NOTCH3	Q9UM47-1.2	P2273L	Pathogenic	0.97
NOTCH3	Q9UM47-1.2	P2273M	Pathogenic	0.875
NOTCH3	Q9UM47-1.2	P2273N	Pathogenic	0.887
NOTCH3	Q9UM47-1.2	P2273Q	Pathogenic	0.617
NOTCH3	Q9UM47-1.2	P2273R	Pathogenic	0.866
NOTCH3	Q9UM47-1.2	P2273S	Pathogenic	0.623
NOTCH3	Q9UM47-1.2	P2273T	Pathogenic	0.635
NOTCH3	Q9UM47-1.2	P2273V	Pathogenic	0.883
NOTCH3	Q9UM47-1.2	P2273W	Pathogenic	0.992
NOTCH3	Q9UM47-1.2	P2273Y	Pathogenic	0.968
NOTCH3	Q9UM47-1.2	A2274C	Neutral	0.007
NOTCH3	Q9UM47-1.2	A2274D	Neutral	0.127
NOTCH3	Q9UM47-1.2	A2274E	Neutral	0.029
NOTCH3	Q9UM47-1.2	A2274F	Neutral	0.11
NOTCH3	Q9UM47-1.2	A2274G	Neutral	0.007
NOTCH3	Q9UM47-1.2	A2274H	Neutral	0.116
NOTCH3	Q9UM47-1.2	A2274I	Neutral	0.028
NOTCH3	Q9UM47-1.2	A2274K	Neutral	0.026
NOTCH3	Q9UM47-1.2	A2274L	Neutral	0.028
NOTCH3	Q9UM47-1.2	A2274M	Neutral	0.027
NOTCH3	Q9UM47-1.2	A2274N	Neutral	0.125
NOTCH3	Q9UM47-1.2	A2274P	Neutral	0.031
NOTCH3	Q9UM47-1.2	A2274Q	Neutral	0.028
NOTCH3	Q9UM47-1.2	A2274R	Neutral	0.025
NOTCH3	Q9UM47-1.2	A2274S	Neutral	0.002
NOTCH3	Q9UM47-1.2	A2274T	Neutral	0.007
NOTCH3	Q9UM47-1.2	A2274V	Neutral	0.007
NOTCH3	Q9UM47-1.2	A2274W	Neutral	0.337
NOTCH3	Q9UM47-1.2	A2274Y	Neutral	0.107
NOTCH3	Q9UM47-1.2	T2275A	Neutral	0.036
NOTCH3	Q9UM47-1.2	T2275C	Neutral	0.157
NOTCH3	Q9UM47-1.2	T2275D	Neutral	0.16
NOTCH3	Q9UM47-1.2	T2275E	Neutral	0.152
NOTCH3	Q9UM47-1.2	T2275F	Neutral	0.427
NOTCH3	Q9UM47-1.2	T2275G	Neutral	0.421
NOTCH3	Q9UM47-1.2	T2275H	Neutral	0.44
NOTCH3	Q9UM47-1.2	T2275I	Neutral	0.146
NOTCH3	Q9UM47-1.2	T2275K	Neutral	0.14
NOTCH3	Q9UM47-1.2	T2275L	Neutral	0.146
NOTCH3	Q9UM47-1.2	T2275M	Neutral	0.145
NOTCH3	Q9UM47-1.2	T2275N	Neutral	0.04
NOTCH3	Q9UM47-1.2	T2275P	Neutral	0.159
NOTCH3	Q9UM47-1.2	T2275Q	Neutral	0.15
NOTCH3	Q9UM47-1.2	T2275R	Neutral	0.134
NOTCH3	Q9UM47-1.2	T2275S	Neutral	0.008
NOTCH3	Q9UM47-1.2	T2275V	Neutral	0.039
NOTCH3	Q9UM47-1.2	T2275W	Neutral	0.402
NOTCH3	Q9UM47-1.2	T2275Y	Neutral	0.42
NOTCH3	Q9UM47-1.2	A2276C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2276D	Neutral	0.056
NOTCH3	Q9UM47-1.2	A2276E	Neutral	0.012
NOTCH3	Q9UM47-1.2	A2276F	Neutral	0.048
NOTCH3	Q9UM47-1.2	A2276G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2276H	Neutral	0.05
NOTCH3	Q9UM47-1.2	A2276I	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2276K	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2276L	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2276M	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2276N	Neutral	0.055
NOTCH3	Q9UM47-1.2	A2276P	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2276Q	Neutral	0.012
NOTCH3	Q9UM47-1.2	A2276R	Neutral	0.01
NOTCH3	Q9UM47-1.2	A2276S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2276T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2276V	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2276W	Neutral	0.171
NOTCH3	Q9UM47-1.2	A2276Y	Neutral	0.046
NOTCH3	Q9UM47-1.2	T2277A	Neutral	0.001
NOTCH3	Q9UM47-1.2	T2277C	Neutral	0.007
NOTCH3	Q9UM47-1.2	T2277D	Neutral	0.007
NOTCH3	Q9UM47-1.2	T2277E	Neutral	0.006
NOTCH3	Q9UM47-1.2	T2277F	Neutral	0.026
NOTCH3	Q9UM47-1.2	T2277G	Neutral	0.026
NOTCH3	Q9UM47-1.2	T2277H	Neutral	0.027
NOTCH3	Q9UM47-1.2	T2277I	Neutral	0.006
NOTCH3	Q9UM47-1.2	T2277K	Neutral	0.006
NOTCH3	Q9UM47-1.2	T2277L	Neutral	0.006
NOTCH3	Q9UM47-1.2	T2277M	Neutral	0.006
NOTCH3	Q9UM47-1.2	T2277N	Neutral	0.001
NOTCH3	Q9UM47-1.2	T2277P	Neutral	0.007
NOTCH3	Q9UM47-1.2	T2277Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	T2277R	Neutral	0.006
NOTCH3	Q9UM47-1.2	T2277S	Neutral	0.0
NOTCH3	Q9UM47-1.2	T2277V	Neutral	0.001
NOTCH3	Q9UM47-1.2	T2277W	Neutral	0.024
NOTCH3	Q9UM47-1.2	T2277Y	Neutral	0.025
NOTCH3	Q9UM47-1.2	G2278A	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2278C	Neutral	0.2
NOTCH3	Q9UM47-1.2	G2278D	Neutral	0.012
NOTCH3	Q9UM47-1.2	G2278E	Neutral	0.048
NOTCH3	Q9UM47-1.2	G2278F	Neutral	0.173
NOTCH3	Q9UM47-1.2	G2278H	Neutral	0.046
NOTCH3	Q9UM47-1.2	G2278I	Neutral	0.498
NOTCH3	Q9UM47-1.2	G2278K	Neutral	0.044
NOTCH3	Q9UM47-1.2	G2278L	Neutral	0.498
NOTCH3	Q9UM47-1.2	G2278M	Neutral	0.178
NOTCH3	Q9UM47-1.2	G2278N	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2278P	Neutral	0.051
NOTCH3	Q9UM47-1.2	G2278Q	Neutral	0.047
NOTCH3	Q9UM47-1.2	G2278R	Neutral	0.042
NOTCH3	Q9UM47-1.2	G2278S	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2278T	Neutral	0.051
NOTCH3	Q9UM47-1.2	G2278V	Neutral	0.189
NOTCH3	Q9UM47-1.2	G2278W	Neutral	0.04
NOTCH3	Q9UM47-1.2	G2278Y	Neutral	0.169
NOTCH3	Q9UM47-1.2	A2279C	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2279D	Neutral	0.028
NOTCH3	Q9UM47-1.2	A2279E	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2279F	Neutral	0.024
NOTCH3	Q9UM47-1.2	A2279G	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2279H	Neutral	0.025
NOTCH3	Q9UM47-1.2	A2279I	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2279K	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2279L	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2279M	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2279N	Neutral	0.028
NOTCH3	Q9UM47-1.2	A2279P	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2279Q	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2279R	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2279S	Neutral	0.0
NOTCH3	Q9UM47-1.2	A2279T	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2279V	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2279W	Neutral	0.091
NOTCH3	Q9UM47-1.2	A2279Y	Neutral	0.023
NOTCH3	Q9UM47-1.2	M2280A	Neutral	0.046
NOTCH3	Q9UM47-1.2	M2280C	Neutral	0.049
NOTCH3	Q9UM47-1.2	M2280D	Pathogenic	0.526
NOTCH3	Q9UM47-1.2	M2280E	Neutral	0.207
NOTCH3	Q9UM47-1.2	M2280F	Neutral	0.013
NOTCH3	Q9UM47-1.2	M2280G	Neutral	0.483
NOTCH3	Q9UM47-1.2	M2280H	Neutral	0.212
NOTCH3	Q9UM47-1.2	M2280I	Neutral	0.003
NOTCH3	Q9UM47-1.2	M2280K	Neutral	0.055
NOTCH3	Q9UM47-1.2	M2280L	Neutral	0.001
NOTCH3	Q9UM47-1.2	M2280N	Neutral	0.199
NOTCH3	Q9UM47-1.2	M2280P	Neutral	0.194
NOTCH3	Q9UM47-1.2	M2280Q	Neutral	0.013
NOTCH3	Q9UM47-1.2	M2280R	Neutral	0.053
NOTCH3	Q9UM47-1.2	M2280S	Neutral	0.047
NOTCH3	Q9UM47-1.2	M2280T	Neutral	0.051
NOTCH3	Q9UM47-1.2	M2280V	Neutral	0.003
NOTCH3	Q9UM47-1.2	M2280W	Neutral	0.049
NOTCH3	Q9UM47-1.2	M2280Y	Neutral	0.053
NOTCH3	Q9UM47-1.2	A2281C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2281D	Neutral	0.053
NOTCH3	Q9UM47-1.2	A2281E	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2281F	Neutral	0.045
NOTCH3	Q9UM47-1.2	A2281G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2281H	Neutral	0.048
NOTCH3	Q9UM47-1.2	A2281I	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2281K	Neutral	0.01
NOTCH3	Q9UM47-1.2	A2281L	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2281M	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2281N	Neutral	0.052
NOTCH3	Q9UM47-1.2	A2281P	Neutral	0.012
NOTCH3	Q9UM47-1.2	A2281Q	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2281R	Neutral	0.01
NOTCH3	Q9UM47-1.2	A2281S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2281T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2281V	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2281W	Neutral	0.163
NOTCH3	Q9UM47-1.2	A2281Y	Neutral	0.044
NOTCH3	Q9UM47-1.2	T2282A	Neutral	0.004
NOTCH3	Q9UM47-1.2	T2282C	Neutral	0.018
NOTCH3	Q9UM47-1.2	T2282D	Neutral	0.018
NOTCH3	Q9UM47-1.2	T2282E	Neutral	0.017
NOTCH3	Q9UM47-1.2	T2282F	Neutral	0.067
NOTCH3	Q9UM47-1.2	T2282G	Neutral	0.066
NOTCH3	Q9UM47-1.2	T2282H	Neutral	0.071
NOTCH3	Q9UM47-1.2	T2282I	Neutral	0.016
NOTCH3	Q9UM47-1.2	T2282K	Neutral	0.016
NOTCH3	Q9UM47-1.2	T2282L	Neutral	0.016
NOTCH3	Q9UM47-1.2	T2282M	Neutral	0.016
NOTCH3	Q9UM47-1.2	T2282N	Neutral	0.004
NOTCH3	Q9UM47-1.2	T2282P	Neutral	0.018
NOTCH3	Q9UM47-1.2	T2282Q	Neutral	0.017
NOTCH3	Q9UM47-1.2	T2282R	Neutral	0.015
NOTCH3	Q9UM47-1.2	T2282S	Neutral	0.001
NOTCH3	Q9UM47-1.2	T2282V	Neutral	0.004
NOTCH3	Q9UM47-1.2	T2282W	Neutral	0.061
NOTCH3	Q9UM47-1.2	T2282Y	Neutral	0.065
NOTCH3	Q9UM47-1.2	T2283A	Neutral	0.001
NOTCH3	Q9UM47-1.2	T2283C	Neutral	0.004
NOTCH3	Q9UM47-1.2	T2283D	Neutral	0.004
NOTCH3	Q9UM47-1.2	T2283E	Neutral	0.004
NOTCH3	Q9UM47-1.2	T2283F	Neutral	0.015
NOTCH3	Q9UM47-1.2	T2283G	Neutral	0.015
NOTCH3	Q9UM47-1.2	T2283H	Neutral	0.016
NOTCH3	Q9UM47-1.2	T2283I	Neutral	0.004
NOTCH3	Q9UM47-1.2	T2283K	Neutral	0.003
NOTCH3	Q9UM47-1.2	T2283L	Neutral	0.004
NOTCH3	Q9UM47-1.2	T2283M	Neutral	0.004
NOTCH3	Q9UM47-1.2	T2283N	Neutral	0.001
NOTCH3	Q9UM47-1.2	T2283P	Neutral	0.004
NOTCH3	Q9UM47-1.2	T2283Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	T2283R	Neutral	0.003
NOTCH3	Q9UM47-1.2	T2283S	Neutral	0.0
NOTCH3	Q9UM47-1.2	T2283V	Neutral	0.001
NOTCH3	Q9UM47-1.2	T2283W	Neutral	0.014
NOTCH3	Q9UM47-1.2	T2283Y	Neutral	0.015
NOTCH3	Q9UM47-1.2	T2284A	Neutral	0.006
NOTCH3	Q9UM47-1.2	T2284C	Neutral	0.027
NOTCH3	Q9UM47-1.2	T2284D	Neutral	0.028
NOTCH3	Q9UM47-1.2	T2284E	Neutral	0.026
NOTCH3	Q9UM47-1.2	T2284F	Neutral	0.101
NOTCH3	Q9UM47-1.2	T2284G	Neutral	0.099
NOTCH3	Q9UM47-1.2	T2284H	Neutral	0.106
NOTCH3	Q9UM47-1.2	T2284I	Neutral	0.025
NOTCH3	Q9UM47-1.2	T2284K	Neutral	0.024
NOTCH3	Q9UM47-1.2	T2284L	Neutral	0.025
NOTCH3	Q9UM47-1.2	T2284M	Neutral	0.025
NOTCH3	Q9UM47-1.2	T2284N	Neutral	0.006
NOTCH3	Q9UM47-1.2	T2284P	Neutral	0.028
NOTCH3	Q9UM47-1.2	T2284Q	Neutral	0.026
NOTCH3	Q9UM47-1.2	T2284R	Neutral	0.023
NOTCH3	Q9UM47-1.2	T2284S	Neutral	0.001
NOTCH3	Q9UM47-1.2	T2284V	Neutral	0.006
NOTCH3	Q9UM47-1.2	T2284W	Neutral	0.092
NOTCH3	Q9UM47-1.2	T2284Y	Neutral	0.099
NOTCH3	Q9UM47-1.2	G2285A	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2285C	Neutral	0.145
NOTCH3	Q9UM47-1.2	G2285D	Neutral	0.008
NOTCH3	Q9UM47-1.2	G2285E	Neutral	0.033
NOTCH3	Q9UM47-1.2	G2285F	Neutral	0.124
NOTCH3	Q9UM47-1.2	G2285H	Neutral	0.032
NOTCH3	Q9UM47-1.2	G2285I	Neutral	0.402
NOTCH3	Q9UM47-1.2	G2285K	Neutral	0.03
NOTCH3	Q9UM47-1.2	G2285L	Neutral	0.402
NOTCH3	Q9UM47-1.2	G2285M	Neutral	0.128
NOTCH3	Q9UM47-1.2	G2285N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2285P	Neutral	0.035
NOTCH3	Q9UM47-1.2	G2285Q	Neutral	0.032
NOTCH3	Q9UM47-1.2	G2285R	Neutral	0.029
NOTCH3	Q9UM47-1.2	G2285S	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2285T	Neutral	0.035
NOTCH3	Q9UM47-1.2	G2285V	Neutral	0.136
NOTCH3	Q9UM47-1.2	G2285W	Neutral	0.027
NOTCH3	Q9UM47-1.2	G2285Y	Neutral	0.121
NOTCH3	Q9UM47-1.2	A2286C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2286D	Neutral	0.055
NOTCH3	Q9UM47-1.2	A2286E	Neutral	0.012
NOTCH3	Q9UM47-1.2	A2286F	Neutral	0.047
NOTCH3	Q9UM47-1.2	A2286G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2286H	Neutral	0.05
NOTCH3	Q9UM47-1.2	A2286I	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2286K	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2286L	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2286M	Neutral	0.011
NOTCH3	Q9UM47-1.2	A2286N	Neutral	0.054
NOTCH3	Q9UM47-1.2	A2286P	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2286Q	Neutral	0.012
NOTCH3	Q9UM47-1.2	A2286R	Neutral	0.01
NOTCH3	Q9UM47-1.2	A2286S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2286T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2286V	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2286W	Neutral	0.169
NOTCH3	Q9UM47-1.2	A2286Y	Neutral	0.046
NOTCH3	Q9UM47-1.2	L2287A	Neutral	0.03
NOTCH3	Q9UM47-1.2	L2287C	Neutral	0.032
NOTCH3	Q9UM47-1.2	L2287D	Pathogenic	0.765
NOTCH3	Q9UM47-1.2	L2287E	Neutral	0.434
NOTCH3	Q9UM47-1.2	L2287F	Neutral	0.008
NOTCH3	Q9UM47-1.2	L2287G	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	L2287H	Neutral	0.441
NOTCH3	Q9UM47-1.2	L2287I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2287K	Neutral	0.146
NOTCH3	Q9UM47-1.2	L2287M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2287N	Neutral	0.421
NOTCH3	Q9UM47-1.2	L2287P	Neutral	0.413
NOTCH3	Q9UM47-1.2	L2287Q	Neutral	0.146
NOTCH3	Q9UM47-1.2	L2287R	Neutral	0.14
NOTCH3	Q9UM47-1.2	L2287S	Neutral	0.127
NOTCH3	Q9UM47-1.2	L2287T	Neutral	0.033
NOTCH3	Q9UM47-1.2	L2287V	Neutral	0.002
NOTCH3	Q9UM47-1.2	L2287W	Neutral	0.131
NOTCH3	Q9UM47-1.2	L2287Y	Neutral	0.035
NOTCH3	Q9UM47-1.2	P2288A	Neutral	0.096
NOTCH3	Q9UM47-1.2	P2288C	Pathogenic	0.703
NOTCH3	Q9UM47-1.2	P2288D	Neutral	0.104
NOTCH3	Q9UM47-1.2	P2288E	Neutral	0.098
NOTCH3	Q9UM47-1.2	P2288F	Pathogenic	0.902
NOTCH3	Q9UM47-1.2	P2288G	Neutral	0.31
NOTCH3	Q9UM47-1.2	P2288H	Neutral	0.322
NOTCH3	Q9UM47-1.2	P2288I	Pathogenic	0.679
NOTCH3	Q9UM47-1.2	P2288K	Neutral	0.09
NOTCH3	Q9UM47-1.2	P2288L	Pathogenic	0.679
NOTCH3	Q9UM47-1.2	P2288M	Neutral	0.316
NOTCH3	Q9UM47-1.2	P2288N	Neutral	0.342
NOTCH3	Q9UM47-1.2	P2288Q	Neutral	0.096
NOTCH3	Q9UM47-1.2	P2288R	Neutral	0.299
NOTCH3	Q9UM47-1.2	P2288S	Neutral	0.098
NOTCH3	Q9UM47-1.2	P2288T	Neutral	0.103
NOTCH3	Q9UM47-1.2	P2288V	Neutral	0.333
NOTCH3	Q9UM47-1.2	P2288W	Pathogenic	0.893
NOTCH3	Q9UM47-1.2	P2288Y	Pathogenic	0.663
NOTCH3	Q9UM47-1.2	A2289C	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2289D	Neutral	0.107
NOTCH3	Q9UM47-1.2	A2289E	Neutral	0.024
NOTCH3	Q9UM47-1.2	A2289F	Neutral	0.092
NOTCH3	Q9UM47-1.2	A2289G	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2289H	Neutral	0.097
NOTCH3	Q9UM47-1.2	A2289I	Neutral	0.023
NOTCH3	Q9UM47-1.2	A2289K	Neutral	0.022
NOTCH3	Q9UM47-1.2	A2289L	Neutral	0.023
NOTCH3	Q9UM47-1.2	A2289M	Neutral	0.023
NOTCH3	Q9UM47-1.2	A2289N	Neutral	0.105
NOTCH3	Q9UM47-1.2	A2289P	Neutral	0.026
NOTCH3	Q9UM47-1.2	A2289Q	Neutral	0.023
NOTCH3	Q9UM47-1.2	A2289R	Neutral	0.021
NOTCH3	Q9UM47-1.2	A2289S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2289T	Neutral	0.006
NOTCH3	Q9UM47-1.2	A2289V	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2289W	Neutral	0.294
NOTCH3	Q9UM47-1.2	A2289Y	Neutral	0.09
NOTCH3	Q9UM47-1.2	Q2290A	Neutral	0.051
NOTCH3	Q9UM47-1.2	Q2290C	Pathogenic	0.544
NOTCH3	Q9UM47-1.2	Q2290D	Neutral	0.013
NOTCH3	Q9UM47-1.2	Q2290E	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q2290F	Pathogenic	0.552
NOTCH3	Q9UM47-1.2	Q2290G	Neutral	0.183
NOTCH3	Q9UM47-1.2	Q2290H	Neutral	0.014
NOTCH3	Q9UM47-1.2	Q2290I	Pathogenic	0.563
NOTCH3	Q9UM47-1.2	Q2290K	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q2290L	Neutral	0.22
NOTCH3	Q9UM47-1.2	Q2290M	Neutral	0.013
NOTCH3	Q9UM47-1.2	Q2290N	Neutral	0.013
NOTCH3	Q9UM47-1.2	Q2290P	Neutral	0.055
NOTCH3	Q9UM47-1.2	Q2290R	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q2290S	Neutral	0.012
NOTCH3	Q9UM47-1.2	Q2290T	Neutral	0.056
NOTCH3	Q9UM47-1.2	Q2290V	Neutral	0.22
NOTCH3	Q9UM47-1.2	Q2290W	Neutral	0.196
NOTCH3	Q9UM47-1.2	Q2290Y	Neutral	0.055
NOTCH3	Q9UM47-1.2	P2291A	Neutral	0.02
NOTCH3	Q9UM47-1.2	P2291C	Neutral	0.312
NOTCH3	Q9UM47-1.2	P2291D	Neutral	0.022
NOTCH3	Q9UM47-1.2	P2291E	Neutral	0.02
NOTCH3	Q9UM47-1.2	P2291F	Pathogenic	0.639
NOTCH3	Q9UM47-1.2	P2291G	Neutral	0.079
NOTCH3	Q9UM47-1.2	P2291H	Neutral	0.083
NOTCH3	Q9UM47-1.2	P2291I	Neutral	0.289
NOTCH3	Q9UM47-1.2	P2291K	Neutral	0.019
NOTCH3	Q9UM47-1.2	P2291L	Neutral	0.289
NOTCH3	Q9UM47-1.2	P2291M	Neutral	0.082
NOTCH3	Q9UM47-1.2	P2291N	Neutral	0.091
NOTCH3	Q9UM47-1.2	P2291Q	Neutral	0.02
NOTCH3	Q9UM47-1.2	P2291R	Neutral	0.076
NOTCH3	Q9UM47-1.2	P2291S	Neutral	0.02
NOTCH3	Q9UM47-1.2	P2291T	Neutral	0.021
NOTCH3	Q9UM47-1.2	P2291V	Neutral	0.087
NOTCH3	Q9UM47-1.2	P2291W	Pathogenic	0.615
NOTCH3	Q9UM47-1.2	P2291Y	Neutral	0.274
NOTCH3	Q9UM47-1.2	L2292A	Neutral	0.016
NOTCH3	Q9UM47-1.2	L2292C	Neutral	0.017
NOTCH3	Q9UM47-1.2	L2292D	Pathogenic	0.633
NOTCH3	Q9UM47-1.2	L2292E	Neutral	0.289
NOTCH3	Q9UM47-1.2	L2292F	Neutral	0.004
NOTCH3	Q9UM47-1.2	L2292G	Pathogenic	0.593
NOTCH3	Q9UM47-1.2	L2292H	Neutral	0.295
NOTCH3	Q9UM47-1.2	L2292I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2292K	Neutral	0.083
NOTCH3	Q9UM47-1.2	L2292M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2292N	Neutral	0.279
NOTCH3	Q9UM47-1.2	L2292P	Neutral	0.272
NOTCH3	Q9UM47-1.2	L2292Q	Neutral	0.083
NOTCH3	Q9UM47-1.2	L2292R	Neutral	0.08
NOTCH3	Q9UM47-1.2	L2292S	Neutral	0.072
NOTCH3	Q9UM47-1.2	L2292T	Neutral	0.018
NOTCH3	Q9UM47-1.2	L2292V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2292W	Neutral	0.074
NOTCH3	Q9UM47-1.2	L2292Y	Neutral	0.019
NOTCH3	Q9UM47-1.2	P2293A	Neutral	0.023
NOTCH3	Q9UM47-1.2	P2293C	Neutral	0.348
NOTCH3	Q9UM47-1.2	P2293D	Neutral	0.026
NOTCH3	Q9UM47-1.2	P2293E	Neutral	0.024
NOTCH3	Q9UM47-1.2	P2293F	Pathogenic	0.676
NOTCH3	Q9UM47-1.2	P2293G	Neutral	0.092
NOTCH3	Q9UM47-1.2	P2293H	Neutral	0.097
NOTCH3	Q9UM47-1.2	P2293I	Neutral	0.324
NOTCH3	Q9UM47-1.2	P2293K	Neutral	0.022
NOTCH3	Q9UM47-1.2	P2293L	Neutral	0.324
NOTCH3	Q9UM47-1.2	P2293M	Neutral	0.095
NOTCH3	Q9UM47-1.2	P2293N	Neutral	0.105
NOTCH3	Q9UM47-1.2	P2293Q	Neutral	0.023
NOTCH3	Q9UM47-1.2	P2293R	Neutral	0.088
NOTCH3	Q9UM47-1.2	P2293S	Neutral	0.024
NOTCH3	Q9UM47-1.2	P2293T	Neutral	0.025
NOTCH3	Q9UM47-1.2	P2293V	Neutral	0.101
NOTCH3	Q9UM47-1.2	P2293W	Pathogenic	0.653
NOTCH3	Q9UM47-1.2	P2293Y	Neutral	0.308
NOTCH3	Q9UM47-1.2	L2294A	Neutral	0.021
NOTCH3	Q9UM47-1.2	L2294C	Neutral	0.022
NOTCH3	Q9UM47-1.2	L2294D	Pathogenic	0.689
NOTCH3	Q9UM47-1.2	L2294E	Neutral	0.342
NOTCH3	Q9UM47-1.2	L2294F	Neutral	0.005
NOTCH3	Q9UM47-1.2	L2294G	Pathogenic	0.651
NOTCH3	Q9UM47-1.2	L2294H	Neutral	0.349
NOTCH3	Q9UM47-1.2	L2294I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2294K	Neutral	0.104
NOTCH3	Q9UM47-1.2	L2294M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2294N	Neutral	0.331
NOTCH3	Q9UM47-1.2	L2294P	Neutral	0.323
NOTCH3	Q9UM47-1.2	L2294Q	Neutral	0.104
NOTCH3	Q9UM47-1.2	L2294R	Neutral	0.1
NOTCH3	Q9UM47-1.2	L2294S	Neutral	0.09
NOTCH3	Q9UM47-1.2	L2294T	Neutral	0.023
NOTCH3	Q9UM47-1.2	L2294V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2294W	Neutral	0.093
NOTCH3	Q9UM47-1.2	L2294Y	Neutral	0.024
NOTCH3	Q9UM47-1.2	S2295A	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2295C	Neutral	0.021
NOTCH3	Q9UM47-1.2	S2295D	Neutral	0.005
NOTCH3	Q9UM47-1.2	S2295E	Neutral	0.004
NOTCH3	Q9UM47-1.2	S2295F	Neutral	0.075
NOTCH3	Q9UM47-1.2	S2295G	Neutral	0.004
NOTCH3	Q9UM47-1.2	S2295H	Neutral	0.018
NOTCH3	Q9UM47-1.2	S2295I	Neutral	0.078
NOTCH3	Q9UM47-1.2	S2295K	Neutral	0.004
NOTCH3	Q9UM47-1.2	S2295L	Neutral	0.078
NOTCH3	Q9UM47-1.2	S2295M	Neutral	0.018
NOTCH3	Q9UM47-1.2	S2295N	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2295P	Neutral	0.021
NOTCH3	Q9UM47-1.2	S2295Q	Neutral	0.004
NOTCH3	Q9UM47-1.2	S2295R	Neutral	0.017
NOTCH3	Q9UM47-1.2	S2295T	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2295V	Neutral	0.083
NOTCH3	Q9UM47-1.2	S2295W	Neutral	0.249
NOTCH3	Q9UM47-1.2	S2295Y	Neutral	0.073
NOTCH3	Q9UM47-1.2	V2296A	Neutral	0.01
NOTCH3	Q9UM47-1.2	V2296C	Neutral	0.046
NOTCH3	Q9UM47-1.2	V2296D	Pathogenic	0.51
NOTCH3	Q9UM47-1.2	V2296E	Neutral	0.192
NOTCH3	Q9UM47-1.2	V2296F	Neutral	0.045
NOTCH3	Q9UM47-1.2	V2296G	Neutral	0.467
NOTCH3	Q9UM47-1.2	V2296H	Pathogenic	0.509
NOTCH3	Q9UM47-1.2	V2296I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V2296K	Neutral	0.177
NOTCH3	Q9UM47-1.2	V2296L	Neutral	0.002
NOTCH3	Q9UM47-1.2	V2296M	Neutral	0.002
NOTCH3	Q9UM47-1.2	V2296N	Pathogenic	0.514
NOTCH3	Q9UM47-1.2	V2296P	Neutral	0.183
NOTCH3	Q9UM47-1.2	V2296Q	Neutral	0.188
NOTCH3	Q9UM47-1.2	V2296R	Neutral	0.482
NOTCH3	Q9UM47-1.2	V2296S	Neutral	0.175
NOTCH3	Q9UM47-1.2	V2296T	Neutral	0.011
NOTCH3	Q9UM47-1.2	V2296W	Neutral	0.465
NOTCH3	Q9UM47-1.2	V2296Y	Neutral	0.043
NOTCH3	Q9UM47-1.2	P2297A	Neutral	0.029
NOTCH3	Q9UM47-1.2	P2297C	Neutral	0.4
NOTCH3	Q9UM47-1.2	P2297D	Neutral	0.032
NOTCH3	Q9UM47-1.2	P2297E	Neutral	0.03
NOTCH3	Q9UM47-1.2	P2297F	Pathogenic	0.723
NOTCH3	Q9UM47-1.2	P2297G	Neutral	0.113
NOTCH3	Q9UM47-1.2	P2297H	Neutral	0.118
NOTCH3	Q9UM47-1.2	P2297I	Neutral	0.374
NOTCH3	Q9UM47-1.2	P2297K	Neutral	0.027
NOTCH3	Q9UM47-1.2	P2297L	Neutral	0.374
NOTCH3	Q9UM47-1.2	P2297M	Neutral	0.116
NOTCH3	Q9UM47-1.2	P2297N	Neutral	0.128
NOTCH3	Q9UM47-1.2	P2297Q	Neutral	0.029
NOTCH3	Q9UM47-1.2	P2297R	Neutral	0.107
NOTCH3	Q9UM47-1.2	P2297S	Neutral	0.03
NOTCH3	Q9UM47-1.2	P2297T	Neutral	0.031
NOTCH3	Q9UM47-1.2	P2297V	Neutral	0.123
NOTCH3	Q9UM47-1.2	P2297W	Pathogenic	0.701
NOTCH3	Q9UM47-1.2	P2297Y	Neutral	0.357
NOTCH3	Q9UM47-1.2	S2298A	Neutral	0.0
NOTCH3	Q9UM47-1.2	S2298C	Neutral	0.006
NOTCH3	Q9UM47-1.2	S2298D	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2298E	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2298F	Neutral	0.023
NOTCH3	Q9UM47-1.2	S2298G	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2298H	Neutral	0.005
NOTCH3	Q9UM47-1.2	S2298I	Neutral	0.024
NOTCH3	Q9UM47-1.2	S2298K	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2298L	Neutral	0.024
NOTCH3	Q9UM47-1.2	S2298M	Neutral	0.005
NOTCH3	Q9UM47-1.2	S2298N	Neutral	0.0
NOTCH3	Q9UM47-1.2	S2298P	Neutral	0.006
NOTCH3	Q9UM47-1.2	S2298Q	Neutral	0.001
NOTCH3	Q9UM47-1.2	S2298R	Neutral	0.005
NOTCH3	Q9UM47-1.2	S2298T	Neutral	0.0
NOTCH3	Q9UM47-1.2	S2298V	Neutral	0.025
NOTCH3	Q9UM47-1.2	S2298W	Neutral	0.088
NOTCH3	Q9UM47-1.2	S2298Y	Neutral	0.022
NOTCH3	Q9UM47-1.2	S2299A	Neutral	0.0
NOTCH3	Q9UM47-1.2	S2299C	Neutral	0.009
NOTCH3	Q9UM47-1.2	S2299D	Neutral	0.002
NOTCH3	Q9UM47-1.2	S2299E	Neutral	0.002
NOTCH3	Q9UM47-1.2	S2299F	Neutral	0.034
NOTCH3	Q9UM47-1.2	S2299G	Neutral	0.002
NOTCH3	Q9UM47-1.2	S2299H	Neutral	0.008
NOTCH3	Q9UM47-1.2	S2299I	Neutral	0.035
NOTCH3	Q9UM47-1.2	S2299K	Neutral	0.002
NOTCH3	Q9UM47-1.2	S2299L	Neutral	0.035
NOTCH3	Q9UM47-1.2	S2299M	Neutral	0.008
NOTCH3	Q9UM47-1.2	S2299N	Neutral	0.0
NOTCH3	Q9UM47-1.2	S2299P	Neutral	0.009
NOTCH3	Q9UM47-1.2	S2299Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	S2299R	Neutral	0.007
NOTCH3	Q9UM47-1.2	S2299T	Neutral	0.0
NOTCH3	Q9UM47-1.2	S2299V	Neutral	0.037
NOTCH3	Q9UM47-1.2	S2299W	Neutral	0.125
NOTCH3	Q9UM47-1.2	S2299Y	Neutral	0.033
NOTCH3	Q9UM47-1.2	L2300A	Neutral	0.026
NOTCH3	Q9UM47-1.2	L2300C	Neutral	0.027
NOTCH3	Q9UM47-1.2	L2300D	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	L2300E	Neutral	0.393
NOTCH3	Q9UM47-1.2	L2300F	Neutral	0.007
NOTCH3	Q9UM47-1.2	L2300G	Pathogenic	0.699
NOTCH3	Q9UM47-1.2	L2300H	Neutral	0.4
NOTCH3	Q9UM47-1.2	L2300I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2300K	Neutral	0.127
NOTCH3	Q9UM47-1.2	L2300M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2300N	Neutral	0.381
NOTCH3	Q9UM47-1.2	L2300P	Neutral	0.374
NOTCH3	Q9UM47-1.2	L2300Q	Neutral	0.126
NOTCH3	Q9UM47-1.2	L2300R	Neutral	0.121
NOTCH3	Q9UM47-1.2	L2300S	Neutral	0.11
NOTCH3	Q9UM47-1.2	L2300T	Neutral	0.028
NOTCH3	Q9UM47-1.2	L2300V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2300W	Neutral	0.113
NOTCH3	Q9UM47-1.2	L2300Y	Neutral	0.03
NOTCH3	Q9UM47-1.2	A2301C	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2301D	Neutral	0.064
NOTCH3	Q9UM47-1.2	A2301E	Neutral	0.014
NOTCH3	Q9UM47-1.2	A2301F	Neutral	0.055
NOTCH3	Q9UM47-1.2	A2301G	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2301H	Neutral	0.058
NOTCH3	Q9UM47-1.2	A2301I	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2301K	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2301L	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2301M	Neutral	0.013
NOTCH3	Q9UM47-1.2	A2301N	Neutral	0.063
NOTCH3	Q9UM47-1.2	A2301P	Neutral	0.015
NOTCH3	Q9UM47-1.2	A2301Q	Neutral	0.014
NOTCH3	Q9UM47-1.2	A2301R	Neutral	0.012
NOTCH3	Q9UM47-1.2	A2301S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2301T	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2301V	Neutral	0.003
NOTCH3	Q9UM47-1.2	A2301W	Neutral	0.192
NOTCH3	Q9UM47-1.2	A2301Y	Neutral	0.053
NOTCH3	Q9UM47-1.2	Q2302A	Neutral	0.063
NOTCH3	Q9UM47-1.2	Q2302C	Pathogenic	0.603
NOTCH3	Q9UM47-1.2	Q2302D	Neutral	0.016
NOTCH3	Q9UM47-1.2	Q2302E	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q2302F	Pathogenic	0.611
NOTCH3	Q9UM47-1.2	Q2302G	Neutral	0.222
NOTCH3	Q9UM47-1.2	Q2302H	Neutral	0.017
NOTCH3	Q9UM47-1.2	Q2302I	Pathogenic	0.621
NOTCH3	Q9UM47-1.2	Q2302K	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q2302L	Neutral	0.264
NOTCH3	Q9UM47-1.2	Q2302M	Neutral	0.017
NOTCH3	Q9UM47-1.2	Q2302N	Neutral	0.016
NOTCH3	Q9UM47-1.2	Q2302P	Neutral	0.069
NOTCH3	Q9UM47-1.2	Q2302R	Neutral	0.003
NOTCH3	Q9UM47-1.2	Q2302S	Neutral	0.015
NOTCH3	Q9UM47-1.2	Q2302T	Neutral	0.07
NOTCH3	Q9UM47-1.2	Q2302V	Neutral	0.264
NOTCH3	Q9UM47-1.2	Q2302W	Neutral	0.237
NOTCH3	Q9UM47-1.2	Q2302Y	Neutral	0.068
NOTCH3	Q9UM47-1.2	A2303C	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2303D	Neutral	0.085
NOTCH3	Q9UM47-1.2	A2303E	Neutral	0.019
NOTCH3	Q9UM47-1.2	A2303F	Neutral	0.073
NOTCH3	Q9UM47-1.2	A2303G	Neutral	0.005
NOTCH3	Q9UM47-1.2	A2303H	Neutral	0.077
NOTCH3	Q9UM47-1.2	A2303I	Neutral	0.018
NOTCH3	Q9UM47-1.2	A2303K	Neutral	0.017
NOTCH3	Q9UM47-1.2	A2303L	Neutral	0.018
NOTCH3	Q9UM47-1.2	A2303M	Neutral	0.018
NOTCH3	Q9UM47-1.2	A2303N	Neutral	0.083
NOTCH3	Q9UM47-1.2	A2303P	Neutral	0.02
NOTCH3	Q9UM47-1.2	A2303Q	Neutral	0.018
NOTCH3	Q9UM47-1.2	A2303R	Neutral	0.016
NOTCH3	Q9UM47-1.2	A2303S	Neutral	0.001
NOTCH3	Q9UM47-1.2	A2303T	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2303V	Neutral	0.004
NOTCH3	Q9UM47-1.2	A2303W	Neutral	0.244
NOTCH3	Q9UM47-1.2	A2303Y	Neutral	0.071
NOTCH3	Q9UM47-1.2	Q2304A	Neutral	0.132
NOTCH3	Q9UM47-1.2	Q2304C	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	Q2304D	Neutral	0.035
NOTCH3	Q9UM47-1.2	Q2304E	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q2304F	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	Q2304G	Neutral	0.391
NOTCH3	Q9UM47-1.2	Q2304H	Neutral	0.038
NOTCH3	Q9UM47-1.2	Q2304I	Pathogenic	0.787
NOTCH3	Q9UM47-1.2	Q2304K	Neutral	0.008
NOTCH3	Q9UM47-1.2	Q2304L	Neutral	0.447
NOTCH3	Q9UM47-1.2	Q2304M	Neutral	0.037
NOTCH3	Q9UM47-1.2	Q2304N	Neutral	0.036
NOTCH3	Q9UM47-1.2	Q2304P	Neutral	0.143
NOTCH3	Q9UM47-1.2	Q2304R	Neutral	0.008
NOTCH3	Q9UM47-1.2	Q2304S	Neutral	0.033
NOTCH3	Q9UM47-1.2	Q2304T	Neutral	0.144
NOTCH3	Q9UM47-1.2	Q2304V	Neutral	0.447
NOTCH3	Q9UM47-1.2	Q2304W	Neutral	0.411
NOTCH3	Q9UM47-1.2	Q2304Y	Neutral	0.142
NOTCH3	Q9UM47-1.2	T2305A	Neutral	0.017
NOTCH3	Q9UM47-1.2	T2305C	Neutral	0.079
NOTCH3	Q9UM47-1.2	T2305D	Neutral	0.081
NOTCH3	Q9UM47-1.2	T2305E	Neutral	0.077
NOTCH3	Q9UM47-1.2	T2305F	Neutral	0.256
NOTCH3	Q9UM47-1.2	T2305G	Neutral	0.251
NOTCH3	Q9UM47-1.2	T2305H	Neutral	0.266
NOTCH3	Q9UM47-1.2	T2305I	Neutral	0.073
NOTCH3	Q9UM47-1.2	T2305K	Neutral	0.07
NOTCH3	Q9UM47-1.2	T2305L	Neutral	0.073
NOTCH3	Q9UM47-1.2	T2305M	Neutral	0.073
NOTCH3	Q9UM47-1.2	T2305N	Neutral	0.019
NOTCH3	Q9UM47-1.2	T2305P	Neutral	0.08
NOTCH3	Q9UM47-1.2	T2305Q	Neutral	0.075
NOTCH3	Q9UM47-1.2	T2305R	Neutral	0.067
NOTCH3	Q9UM47-1.2	T2305S	Neutral	0.004
NOTCH3	Q9UM47-1.2	T2305V	Neutral	0.018
NOTCH3	Q9UM47-1.2	T2305W	Neutral	0.236
NOTCH3	Q9UM47-1.2	T2305Y	Neutral	0.25
NOTCH3	Q9UM47-1.2	Q2306A	Neutral	0.298
NOTCH3	Q9UM47-1.2	Q2306C	Pathogenic	0.905
NOTCH3	Q9UM47-1.2	Q2306D	Neutral	0.093
NOTCH3	Q9UM47-1.2	Q2306E	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q2306F	Pathogenic	0.908
NOTCH3	Q9UM47-1.2	Q2306G	Pathogenic	0.642
NOTCH3	Q9UM47-1.2	Q2306H	Neutral	0.099
NOTCH3	Q9UM47-1.2	Q2306I	Pathogenic	0.911
NOTCH3	Q9UM47-1.2	Q2306K	Neutral	0.022
NOTCH3	Q9UM47-1.2	Q2306L	Pathogenic	0.693
NOTCH3	Q9UM47-1.2	Q2306M	Neutral	0.098
NOTCH3	Q9UM47-1.2	Q2306N	Neutral	0.094
NOTCH3	Q9UM47-1.2	Q2306P	Neutral	0.317
NOTCH3	Q9UM47-1.2	Q2306R	Neutral	0.021
NOTCH3	Q9UM47-1.2	Q2306S	Neutral	0.087
NOTCH3	Q9UM47-1.2	Q2306T	Neutral	0.319
NOTCH3	Q9UM47-1.2	Q2306V	Pathogenic	0.692
NOTCH3	Q9UM47-1.2	Q2306W	Pathogenic	0.661
NOTCH3	Q9UM47-1.2	Q2306Y	Neutral	0.315
NOTCH3	Q9UM47-1.2	L2307A	Neutral	0.01
NOTCH3	Q9UM47-1.2	L2307C	Neutral	0.01
NOTCH3	Q9UM47-1.2	L2307D	Pathogenic	0.506
NOTCH3	Q9UM47-1.2	L2307E	Neutral	0.194
NOTCH3	Q9UM47-1.2	L2307F	Neutral	0.003
NOTCH3	Q9UM47-1.2	L2307G	Neutral	0.463
NOTCH3	Q9UM47-1.2	L2307H	Neutral	0.198
NOTCH3	Q9UM47-1.2	L2307I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2307K	Neutral	0.051
NOTCH3	Q9UM47-1.2	L2307M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2307N	Neutral	0.186
NOTCH3	Q9UM47-1.2	L2307P	Neutral	0.181
NOTCH3	Q9UM47-1.2	L2307Q	Neutral	0.051
NOTCH3	Q9UM47-1.2	L2307R	Neutral	0.049
NOTCH3	Q9UM47-1.2	L2307S	Neutral	0.044
NOTCH3	Q9UM47-1.2	L2307T	Neutral	0.011
NOTCH3	Q9UM47-1.2	L2307V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2307W	Neutral	0.045
NOTCH3	Q9UM47-1.2	L2307Y	Neutral	0.011
NOTCH3	Q9UM47-1.2	G2308A	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2308C	Neutral	0.198
NOTCH3	Q9UM47-1.2	G2308D	Neutral	0.012
NOTCH3	Q9UM47-1.2	G2308E	Neutral	0.047
NOTCH3	Q9UM47-1.2	G2308F	Neutral	0.17
NOTCH3	Q9UM47-1.2	G2308H	Neutral	0.045
NOTCH3	Q9UM47-1.2	G2308I	Neutral	0.494
NOTCH3	Q9UM47-1.2	G2308K	Neutral	0.043
NOTCH3	Q9UM47-1.2	G2308L	Neutral	0.494
NOTCH3	Q9UM47-1.2	G2308M	Neutral	0.176
NOTCH3	Q9UM47-1.2	G2308N	Neutral	0.002
NOTCH3	Q9UM47-1.2	G2308P	Neutral	0.051
NOTCH3	Q9UM47-1.2	G2308Q	Neutral	0.046
NOTCH3	Q9UM47-1.2	G2308R	Neutral	0.041
NOTCH3	Q9UM47-1.2	G2308S	Neutral	0.003
NOTCH3	Q9UM47-1.2	G2308T	Neutral	0.05
NOTCH3	Q9UM47-1.2	G2308V	Neutral	0.187
NOTCH3	Q9UM47-1.2	G2308W	Neutral	0.039
NOTCH3	Q9UM47-1.2	G2308Y	Neutral	0.166
NOTCH3	Q9UM47-1.2	P2309A	Neutral	0.007
NOTCH3	Q9UM47-1.2	P2309C	Neutral	0.141
NOTCH3	Q9UM47-1.2	P2309D	Neutral	0.008
NOTCH3	Q9UM47-1.2	P2309E	Neutral	0.007
NOTCH3	Q9UM47-1.2	P2309F	Neutral	0.39
NOTCH3	Q9UM47-1.2	P2309G	Neutral	0.03
NOTCH3	Q9UM47-1.2	P2309H	Neutral	0.032
NOTCH3	Q9UM47-1.2	P2309I	Neutral	0.128
NOTCH3	Q9UM47-1.2	P2309K	Neutral	0.007
NOTCH3	Q9UM47-1.2	P2309L	Neutral	0.128
NOTCH3	Q9UM47-1.2	P2309M	Neutral	0.031
NOTCH3	Q9UM47-1.2	P2309N	Neutral	0.035
NOTCH3	Q9UM47-1.2	P2309Q	Neutral	0.007
NOTCH3	Q9UM47-1.2	P2309R	Neutral	0.029
NOTCH3	Q9UM47-1.2	P2309S	Neutral	0.007
NOTCH3	Q9UM47-1.2	P2309T	Neutral	0.008
NOTCH3	Q9UM47-1.2	P2309V	Neutral	0.033
NOTCH3	Q9UM47-1.2	P2309W	Neutral	0.366
NOTCH3	Q9UM47-1.2	P2309Y	Neutral	0.12
NOTCH3	Q9UM47-1.2	Q2310A	Neutral	0.018
NOTCH3	Q9UM47-1.2	Q2310C	Neutral	0.29
NOTCH3	Q9UM47-1.2	Q2310D	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q2310E	Neutral	0.0
NOTCH3	Q9UM47-1.2	Q2310F	Neutral	0.297
NOTCH3	Q9UM47-1.2	Q2310G	Neutral	0.071
NOTCH3	Q9UM47-1.2	Q2310H	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q2310I	Neutral	0.306
NOTCH3	Q9UM47-1.2	Q2310K	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q2310L	Neutral	0.088
NOTCH3	Q9UM47-1.2	Q2310M	Neutral	0.005
NOTCH3	Q9UM47-1.2	Q2310N	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q2310P	Neutral	0.02
NOTCH3	Q9UM47-1.2	Q2310R	Neutral	0.001
NOTCH3	Q9UM47-1.2	Q2310S	Neutral	0.004
NOTCH3	Q9UM47-1.2	Q2310T	Neutral	0.02
NOTCH3	Q9UM47-1.2	Q2310V	Neutral	0.088
NOTCH3	Q9UM47-1.2	Q2310W	Neutral	0.077
NOTCH3	Q9UM47-1.2	Q2310Y	Neutral	0.019
NOTCH3	Q9UM47-1.2	P2311A	Neutral	0.236
NOTCH3	Q9UM47-1.2	P2311C	Pathogenic	0.873
NOTCH3	Q9UM47-1.2	P2311D	Neutral	0.253
NOTCH3	Q9UM47-1.2	P2311E	Neutral	0.24
NOTCH3	Q9UM47-1.2	P2311F	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	P2311G	Pathogenic	0.567
NOTCH3	Q9UM47-1.2	P2311H	Pathogenic	0.58
NOTCH3	Q9UM47-1.2	P2311I	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	P2311K	Neutral	0.223
NOTCH3	Q9UM47-1.2	P2311L	Pathogenic	0.86
NOTCH3	Q9UM47-1.2	P2311M	Pathogenic	0.574
NOTCH3	Q9UM47-1.2	P2311N	Pathogenic	0.602
NOTCH3	Q9UM47-1.2	P2311Q	Neutral	0.236
NOTCH3	Q9UM47-1.2	P2311R	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	P2311S	Neutral	0.241
NOTCH3	Q9UM47-1.2	P2311T	Neutral	0.25
NOTCH3	Q9UM47-1.2	P2311V	Pathogenic	0.592
NOTCH3	Q9UM47-1.2	P2311W	Pathogenic	0.96
NOTCH3	Q9UM47-1.2	P2311Y	Pathogenic	0.852
NOTCH3	Q9UM47-1.2	E2312A	Neutral	0.207
NOTCH3	Q9UM47-1.2	E2312C	Pathogenic	0.964
NOTCH3	Q9UM47-1.2	E2312D	Neutral	0.003
NOTCH3	Q9UM47-1.2	E2312F	Pathogenic	0.854
NOTCH3	Q9UM47-1.2	E2312G	Pathogenic	0.525
NOTCH3	Q9UM47-1.2	E2312H	Neutral	0.061
NOTCH3	Q9UM47-1.2	E2312I	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	E2312K	Neutral	0.013
NOTCH3	Q9UM47-1.2	E2312L	Pathogenic	0.859
NOTCH3	Q9UM47-1.2	E2312M	Pathogenic	0.571
NOTCH3	Q9UM47-1.2	E2312N	Neutral	0.06
NOTCH3	Q9UM47-1.2	E2312P	Neutral	0.223
NOTCH3	Q9UM47-1.2	E2312Q	Neutral	0.003
NOTCH3	Q9UM47-1.2	E2312R	Neutral	0.055
NOTCH3	Q9UM47-1.2	E2312S	Neutral	0.055
NOTCH3	Q9UM47-1.2	E2312T	Neutral	0.224
NOTCH3	Q9UM47-1.2	E2312V	Pathogenic	0.581
NOTCH3	Q9UM47-1.2	E2312W	Pathogenic	0.84
NOTCH3	Q9UM47-1.2	E2312Y	Pathogenic	0.554
NOTCH3	Q9UM47-1.2	V2313A	Neutral	0.003
NOTCH3	Q9UM47-1.2	V2313C	Neutral	0.016
NOTCH3	Q9UM47-1.2	V2313D	Neutral	0.26
NOTCH3	Q9UM47-1.2	V2313E	Neutral	0.074
NOTCH3	Q9UM47-1.2	V2313F	Neutral	0.016
NOTCH3	Q9UM47-1.2	V2313G	Neutral	0.229
NOTCH3	Q9UM47-1.2	V2313H	Neutral	0.26
NOTCH3	Q9UM47-1.2	V2313I	Neutral	0.0
NOTCH3	Q9UM47-1.2	V2313K	Neutral	0.068
NOTCH3	Q9UM47-1.2	V2313L	Neutral	0.001
NOTCH3	Q9UM47-1.2	V2313M	Neutral	0.001
NOTCH3	Q9UM47-1.2	V2313N	Neutral	0.264
NOTCH3	Q9UM47-1.2	V2313P	Neutral	0.071
NOTCH3	Q9UM47-1.2	V2313Q	Neutral	0.073
NOTCH3	Q9UM47-1.2	V2313R	Neutral	0.24
NOTCH3	Q9UM47-1.2	V2313S	Neutral	0.067
NOTCH3	Q9UM47-1.2	V2313T	Neutral	0.004
NOTCH3	Q9UM47-1.2	V2313W	Neutral	0.228
NOTCH3	Q9UM47-1.2	V2313Y	Neutral	0.015
NOTCH3	Q9UM47-1.2	T2314A	Neutral	0.002
NOTCH3	Q9UM47-1.2	T2314C	Neutral	0.012
NOTCH3	Q9UM47-1.2	T2314D	Neutral	0.012
NOTCH3	Q9UM47-1.2	T2314E	Neutral	0.011
NOTCH3	Q9UM47-1.2	T2314F	Neutral	0.046
NOTCH3	Q9UM47-1.2	T2314G	Neutral	0.045
NOTCH3	Q9UM47-1.2	T2314H	Neutral	0.048
NOTCH3	Q9UM47-1.2	T2314I	Neutral	0.011
NOTCH3	Q9UM47-1.2	T2314K	Neutral	0.01
NOTCH3	Q9UM47-1.2	T2314L	Neutral	0.011
NOTCH3	Q9UM47-1.2	T2314M	Neutral	0.011
NOTCH3	Q9UM47-1.2	T2314N	Neutral	0.003
NOTCH3	Q9UM47-1.2	T2314P	Neutral	0.012
NOTCH3	Q9UM47-1.2	T2314Q	Neutral	0.011
NOTCH3	Q9UM47-1.2	T2314R	Neutral	0.01
NOTCH3	Q9UM47-1.2	T2314S	Neutral	0.001
NOTCH3	Q9UM47-1.2	T2314V	Neutral	0.003
NOTCH3	Q9UM47-1.2	T2314W	Neutral	0.041
NOTCH3	Q9UM47-1.2	T2314Y	Neutral	0.044
NOTCH3	Q9UM47-1.2	P2315A	Neutral	0.007
NOTCH3	Q9UM47-1.2	P2315C	Neutral	0.135
NOTCH3	Q9UM47-1.2	P2315D	Neutral	0.008
NOTCH3	Q9UM47-1.2	P2315E	Neutral	0.007
NOTCH3	Q9UM47-1.2	P2315F	Neutral	0.379
NOTCH3	Q9UM47-1.2	P2315G	Neutral	0.029
NOTCH3	Q9UM47-1.2	P2315H	Neutral	0.03
NOTCH3	Q9UM47-1.2	P2315I	Neutral	0.123
NOTCH3	Q9UM47-1.2	P2315K	Neutral	0.006
NOTCH3	Q9UM47-1.2	P2315L	Neutral	0.122
NOTCH3	Q9UM47-1.2	P2315M	Neutral	0.03
NOTCH3	Q9UM47-1.2	P2315N	Neutral	0.033
NOTCH3	Q9UM47-1.2	P2315Q	Neutral	0.007
NOTCH3	Q9UM47-1.2	P2315R	Neutral	0.027
NOTCH3	Q9UM47-1.2	P2315S	Neutral	0.007
NOTCH3	Q9UM47-1.2	P2315T	Neutral	0.007
NOTCH3	Q9UM47-1.2	P2315V	Neutral	0.032
NOTCH3	Q9UM47-1.2	P2315W	Neutral	0.354
NOTCH3	Q9UM47-1.2	P2315Y	Neutral	0.115
NOTCH3	Q9UM47-1.2	K2316A	Neutral	0.396
NOTCH3	Q9UM47-1.2	K2316C	Pathogenic	0.936
NOTCH3	Q9UM47-1.2	K2316D	Neutral	0.416
NOTCH3	Q9UM47-1.2	K2316E	Neutral	0.036
NOTCH3	Q9UM47-1.2	K2316F	Pathogenic	0.947
NOTCH3	Q9UM47-1.2	K2316G	Pathogenic	0.734
NOTCH3	Q9UM47-1.2	K2316H	Neutral	0.443
NOTCH3	Q9UM47-1.2	K2316I	Pathogenic	0.945
NOTCH3	Q9UM47-1.2	K2316L	Pathogenic	0.79
NOTCH3	Q9UM47-1.2	K2316M	Neutral	0.451
NOTCH3	Q9UM47-1.2	K2316N	Neutral	0.138
NOTCH3	Q9UM47-1.2	K2316P	Neutral	0.418
NOTCH3	Q9UM47-1.2	K2316Q	Neutral	0.036
NOTCH3	Q9UM47-1.2	K2316R	Neutral	0.008
NOTCH3	Q9UM47-1.2	K2316S	Neutral	0.128
NOTCH3	Q9UM47-1.2	K2316T	Neutral	0.42
NOTCH3	Q9UM47-1.2	K2316V	Pathogenic	0.777
NOTCH3	Q9UM47-1.2	K2316W	Pathogenic	0.941
NOTCH3	Q9UM47-1.2	K2316Y	Pathogenic	0.792
NOTCH3	Q9UM47-1.2	R2317A	Neutral	0.041
NOTCH3	Q9UM47-1.2	R2317C	Neutral	0.492
NOTCH3	Q9UM47-1.2	R2317D	Neutral	0.176
NOTCH3	Q9UM47-1.2	R2317E	Neutral	0.011
NOTCH3	Q9UM47-1.2	R2317F	Pathogenic	0.541
NOTCH3	Q9UM47-1.2	R2317G	Neutral	0.154
NOTCH3	Q9UM47-1.2	R2317H	Neutral	0.011
NOTCH3	Q9UM47-1.2	R2317I	Pathogenic	0.53
NOTCH3	Q9UM47-1.2	R2317K	Neutral	0.001
NOTCH3	Q9UM47-1.2	R2317L	Neutral	0.198
NOTCH3	Q9UM47-1.2	R2317M	Neutral	0.051
NOTCH3	Q9UM47-1.2	R2317N	Neutral	0.01
NOTCH3	Q9UM47-1.2	R2317P	Neutral	0.177
NOTCH3	Q9UM47-1.2	R2317Q	Neutral	0.002
NOTCH3	Q9UM47-1.2	R2317S	Neutral	0.042
NOTCH3	Q9UM47-1.2	R2317T	Neutral	0.046
NOTCH3	Q9UM47-1.2	R2317V	Pathogenic	0.511
NOTCH3	Q9UM47-1.2	R2317W	Pathogenic	0.54
NOTCH3	Q9UM47-1.2	R2317Y	Neutral	0.208
NOTCH3	Q9UM47-1.2	Q2318A	Neutral	0.132
NOTCH3	Q9UM47-1.2	Q2318C	Pathogenic	0.773
NOTCH3	Q9UM47-1.2	Q2318D	Neutral	0.035
NOTCH3	Q9UM47-1.2	Q2318E	Neutral	0.002
NOTCH3	Q9UM47-1.2	Q2318F	Pathogenic	0.779
NOTCH3	Q9UM47-1.2	Q2318G	Neutral	0.391
NOTCH3	Q9UM47-1.2	Q2318H	Neutral	0.038
NOTCH3	Q9UM47-1.2	Q2318I	Pathogenic	0.786
NOTCH3	Q9UM47-1.2	Q2318K	Neutral	0.008
NOTCH3	Q9UM47-1.2	Q2318L	Neutral	0.447
NOTCH3	Q9UM47-1.2	Q2318M	Neutral	0.037
NOTCH3	Q9UM47-1.2	Q2318N	Neutral	0.036
NOTCH3	Q9UM47-1.2	Q2318P	Neutral	0.143
NOTCH3	Q9UM47-1.2	Q2318R	Neutral	0.008
NOTCH3	Q9UM47-1.2	Q2318S	Neutral	0.033
NOTCH3	Q9UM47-1.2	Q2318T	Neutral	0.144
NOTCH3	Q9UM47-1.2	Q2318V	Neutral	0.447
NOTCH3	Q9UM47-1.2	Q2318W	Neutral	0.411
NOTCH3	Q9UM47-1.2	Q2318Y	Neutral	0.142
NOTCH3	Q9UM47-1.2	V2319A	Neutral	0.113
NOTCH3	Q9UM47-1.2	V2319C	Neutral	0.382
NOTCH3	Q9UM47-1.2	V2319D	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	V2319E	Pathogenic	0.751
NOTCH3	Q9UM47-1.2	V2319F	Neutral	0.373
NOTCH3	Q9UM47-1.2	V2319G	Pathogenic	0.918
NOTCH3	Q9UM47-1.2	V2319H	Pathogenic	0.93
NOTCH3	Q9UM47-1.2	V2319I	Neutral	0.001
NOTCH3	Q9UM47-1.2	V2319K	Pathogenic	0.733
NOTCH3	Q9UM47-1.2	V2319L	Neutral	0.029
NOTCH3	Q9UM47-1.2	V2319M	Neutral	0.029
NOTCH3	Q9UM47-1.2	V2319N	Pathogenic	0.931
NOTCH3	Q9UM47-1.2	V2319P	Pathogenic	0.741
NOTCH3	Q9UM47-1.2	V2319Q	Pathogenic	0.747
NOTCH3	Q9UM47-1.2	V2319R	Pathogenic	0.922
NOTCH3	Q9UM47-1.2	V2319S	Pathogenic	0.73
NOTCH3	Q9UM47-1.2	V2319T	Neutral	0.123
NOTCH3	Q9UM47-1.2	V2319W	Pathogenic	0.917
NOTCH3	Q9UM47-1.2	V2319Y	Neutral	0.367
NOTCH3	Q9UM47-1.2	L2320A	Neutral	0.014
NOTCH3	Q9UM47-1.2	L2320C	Neutral	0.015
NOTCH3	Q9UM47-1.2	L2320D	Pathogenic	0.603
NOTCH3	Q9UM47-1.2	L2320E	Neutral	0.263
NOTCH3	Q9UM47-1.2	L2320F	Neutral	0.004
NOTCH3	Q9UM47-1.2	L2320G	Pathogenic	0.561
NOTCH3	Q9UM47-1.2	L2320H	Neutral	0.269
NOTCH3	Q9UM47-1.2	L2320I	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2320K	Neutral	0.074
NOTCH3	Q9UM47-1.2	L2320M	Neutral	0.0
NOTCH3	Q9UM47-1.2	L2320N	Neutral	0.254
NOTCH3	Q9UM47-1.2	L2320P	Neutral	0.247
NOTCH3	Q9UM47-1.2	L2320Q	Neutral	0.074
NOTCH3	Q9UM47-1.2	L2320R	Neutral	0.071
NOTCH3	Q9UM47-1.2	L2320S	Neutral	0.064
NOTCH3	Q9UM47-1.2	L2320T	Neutral	0.016
NOTCH3	Q9UM47-1.2	L2320V	Neutral	0.001
NOTCH3	Q9UM47-1.2	L2320W	Neutral	0.066
NOTCH3	Q9UM47-1.2	L2320Y	Neutral	0.017
NOTCH3	Q9UM47-1.2	A2321C	Neutral	0.066
NOTCH3	Q9UM47-1.2	A2321D	Pathogenic	0.591
NOTCH3	Q9UM47-1.2	A2321E	Neutral	0.228
NOTCH3	Q9UM47-1.2	A2321F	Pathogenic	0.55
NOTCH3	Q9UM47-1.2	A2321G	Neutral	0.066
NOTCH3	Q9UM47-1.2	A2321H	Pathogenic	0.564
NOTCH3	Q9UM47-1.2	A2321I	Neutral	0.219
NOTCH3	Q9UM47-1.2	A2321K	Neutral	0.211
NOTCH3	Q9UM47-1.2	A2321L	Neutral	0.219
NOTCH3	Q9UM47-1.2	A2321M	Neutral	0.218
NOTCH3	Q9UM47-1.2	A2321N	Pathogenic	0.586
NOTCH3	Q9UM47-1.2	A2321P	Neutral	0.24
NOTCH3	Q9UM47-1.2	A2321Q	Neutral	0.224
NOTCH3	Q9UM47-1.2	A2321R	Neutral	0.203
NOTCH3	Q9UM47-1.2	A2321S	Neutral	0.016
NOTCH3	Q9UM47-1.2	A2321T	Neutral	0.064
NOTCH3	Q9UM47-1.2	A2321V	Neutral	0.062
NOTCH3	Q9UM47-1.2	A2321W	Pathogenic	0.834
NOTCH3	Q9UM47-1.2	A2321Y	Pathogenic	0.543