Gene	UniProt	Variant	Prediction	Score
BRCA1	P38398-1.2	M1A	Pathogenic	0.9
BRCA1	P38398-1.2	M1C	Pathogenic	0.856
BRCA1	P38398-1.2	M1D	Pathogenic	0.914
BRCA1	P38398-1.2	M1E	Pathogenic	0.833
BRCA1	P38398-1.2	M1F	Pathogenic	0.693
BRCA1	P38398-1.2	M1G	Pathogenic	0.966
BRCA1	P38398-1.2	M1H	Pathogenic	0.805
BRCA1	P38398-1.2	M1I	Pathogenic	0.551
BRCA1	P38398-1.2	M1K	Pathogenic	0.759
BRCA1	P38398-1.2	M1L	Neutral	0.461
BRCA1	P38398-1.2	M1N	Pathogenic	0.869
BRCA1	P38398-1.2	M1P	Pathogenic	0.886
BRCA1	P38398-1.2	M1Q	Pathogenic	0.684
BRCA1	P38398-1.2	M1R	Pathogenic	0.807
BRCA1	P38398-1.2	M1S	Pathogenic	0.886
BRCA1	P38398-1.2	M1T	Pathogenic	0.834
BRCA1	P38398-1.2	M1V	Pathogenic	0.654
BRCA1	P38398-1.2	M1W	Pathogenic	0.857
BRCA1	P38398-1.2	M1Y	Pathogenic	0.789
BRCA1	P38398-1.2	D2A	Pathogenic	0.591
BRCA1	P38398-1.2	D2C	Pathogenic	0.574
BRCA1	P38398-1.2	D2E	Neutral	0.231
BRCA1	P38398-1.2	D2F	Pathogenic	0.759
BRCA1	P38398-1.2	D2G	Pathogenic	0.607
BRCA1	P38398-1.2	D2H	Pathogenic	0.519
BRCA1	P38398-1.2	D2I	Pathogenic	0.712
BRCA1	P38398-1.2	D2K	Pathogenic	0.614
BRCA1	P38398-1.2	D2L	Pathogenic	0.781
BRCA1	P38398-1.2	D2M	Pathogenic	0.714
BRCA1	P38398-1.2	D2N	Neutral	0.245
BRCA1	P38398-1.2	D2P	Neutral	0.374
BRCA1	P38398-1.2	D2Q	Neutral	0.408
BRCA1	P38398-1.2	D2R	Pathogenic	0.754
BRCA1	P38398-1.2	D2S	Neutral	0.381
BRCA1	P38398-1.2	D2T	Neutral	0.382
BRCA1	P38398-1.2	D2V	Pathogenic	0.621
BRCA1	P38398-1.2	D2W	Pathogenic	0.893
BRCA1	P38398-1.2	D2Y	Pathogenic	0.786
BRCA1	P38398-1.2	L3A	Neutral	0.174
BRCA1	P38398-1.2	L3C	Neutral	0.123
BRCA1	P38398-1.2	L3D	Neutral	0.265
BRCA1	P38398-1.2	L3E	Neutral	0.144
BRCA1	P38398-1.2	L3F	Neutral	0.051
BRCA1	P38398-1.2	L3G	Neutral	0.487
BRCA1	P38398-1.2	L3H	Neutral	0.123
BRCA1	P38398-1.2	L3I	Neutral	0.02
BRCA1	P38398-1.2	L3K	Neutral	0.096
BRCA1	P38398-1.2	L3M	Neutral	0.02
BRCA1	P38398-1.2	L3N	Neutral	0.184
BRCA1	P38398-1.2	L3P	Neutral	0.209
BRCA1	P38398-1.2	L3Q	Neutral	0.095
BRCA1	P38398-1.2	L3R	Neutral	0.124
BRCA1	P38398-1.2	L3S	Neutral	0.208
BRCA1	P38398-1.2	L3T	Neutral	0.105
BRCA1	P38398-1.2	L3V	Neutral	0.043
BRCA1	P38398-1.2	L3W	Neutral	0.171
BRCA1	P38398-1.2	L3Y	Neutral	0.081
BRCA1	P38398-1.2	S4A	Neutral	0.059
BRCA1	P38398-1.2	S4C	Neutral	0.13
BRCA1	P38398-1.2	S4D	Neutral	0.104
BRCA1	P38398-1.2	S4E	Neutral	0.148
BRCA1	P38398-1.2	S4F	Neutral	0.386
BRCA1	P38398-1.2	S4G	Neutral	0.121
BRCA1	P38398-1.2	S4H	Neutral	0.236
BRCA1	P38398-1.2	S4I	Neutral	0.33
BRCA1	P38398-1.2	S4K	Neutral	0.236
BRCA1	P38398-1.2	S4L	Neutral	0.33
BRCA1	P38398-1.2	S4M	Neutral	0.257
BRCA1	P38398-1.2	S4N	Neutral	0.083
BRCA1	P38398-1.2	S4P	Neutral	0.141
BRCA1	P38398-1.2	S4Q	Neutral	0.164
BRCA1	P38398-1.2	S4R	Neutral	0.372
BRCA1	P38398-1.2	S4T	Neutral	0.079
BRCA1	P38398-1.2	S4V	Neutral	0.246
BRCA1	P38398-1.2	S4W	Pathogenic	0.625
BRCA1	P38398-1.2	S4Y	Neutral	0.422
BRCA1	P38398-1.2	A5C	Neutral	0.01
BRCA1	P38398-1.2	A5D	Neutral	0.023
BRCA1	P38398-1.2	A5E	Neutral	0.024
BRCA1	P38398-1.2	A5F	Neutral	0.058
BRCA1	P38398-1.2	A5G	Neutral	0.01
BRCA1	P38398-1.2	A5H	Neutral	0.041
BRCA1	P38398-1.2	A5I	Neutral	0.032
BRCA1	P38398-1.2	A5K	Neutral	0.041
BRCA1	P38398-1.2	A5L	Neutral	0.032
BRCA1	P38398-1.2	A5M	Neutral	0.033
BRCA1	P38398-1.2	A5N	Neutral	0.025
BRCA1	P38398-1.2	A5P	Neutral	0.016
BRCA1	P38398-1.2	A5Q	Neutral	0.026
BRCA1	P38398-1.2	A5R	Neutral	0.054
BRCA1	P38398-1.2	A5S	Neutral	0.005
BRCA1	P38398-1.2	A5T	Neutral	0.012
BRCA1	P38398-1.2	A5V	Neutral	0.015
BRCA1	P38398-1.2	A5W	Neutral	0.14
BRCA1	P38398-1.2	A5Y	Neutral	0.066
BRCA1	P38398-1.2	L6A	Neutral	0.022
BRCA1	P38398-1.2	L6C	Neutral	0.015
BRCA1	P38398-1.2	L6D	Neutral	0.038
BRCA1	P38398-1.2	L6E	Neutral	0.018
BRCA1	P38398-1.2	L6F	Neutral	0.006
BRCA1	P38398-1.2	L6G	Neutral	0.093
BRCA1	P38398-1.2	L6H	Neutral	0.015
BRCA1	P38398-1.2	L6I	Neutral	0.002
BRCA1	P38398-1.2	L6K	Neutral	0.011
BRCA1	P38398-1.2	L6M	Neutral	0.002
BRCA1	P38398-1.2	L6N	Neutral	0.024
BRCA1	P38398-1.2	L6P	Neutral	0.028
BRCA1	P38398-1.2	L6Q	Neutral	0.011
BRCA1	P38398-1.2	L6R	Neutral	0.015
BRCA1	P38398-1.2	L6S	Neutral	0.028
BRCA1	P38398-1.2	L6T	Neutral	0.013
BRCA1	P38398-1.2	L6V	Neutral	0.005
BRCA1	P38398-1.2	L6W	Neutral	0.022
BRCA1	P38398-1.2	L6Y	Neutral	0.009
BRCA1	P38398-1.2	R7A	Neutral	0.162
BRCA1	P38398-1.2	R7C	Neutral	0.206
BRCA1	P38398-1.2	R7D	Neutral	0.143
BRCA1	P38398-1.2	R7E	Neutral	0.051
BRCA1	P38398-1.2	R7F	Neutral	0.079
BRCA1	P38398-1.2	R7G	Neutral	0.299
BRCA1	P38398-1.2	R7H	Neutral	0.042
BRCA1	P38398-1.2	R7I	Neutral	0.099
BRCA1	P38398-1.2	R7K	Neutral	0.014
BRCA1	P38398-1.2	R7L	Neutral	0.071
BRCA1	P38398-1.2	R7M	Neutral	0.051
BRCA1	P38398-1.2	R7N	Neutral	0.067
BRCA1	P38398-1.2	R7P	Neutral	0.142
BRCA1	P38398-1.2	R7Q	Neutral	0.032
BRCA1	P38398-1.2	R7S	Neutral	0.146
BRCA1	P38398-1.2	R7T	Neutral	0.098
BRCA1	P38398-1.2	R7V	Neutral	0.145
BRCA1	P38398-1.2	R7W	Neutral	0.082
BRCA1	P38398-1.2	R7Y	Neutral	0.05
BRCA1	P38398-1.2	V8A	Neutral	0.109
BRCA1	P38398-1.2	V8C	Neutral	0.105
BRCA1	P38398-1.2	V8D	Neutral	0.173
BRCA1	P38398-1.2	V8E	Neutral	0.105
BRCA1	P38398-1.2	V8F	Neutral	0.129
BRCA1	P38398-1.2	V8G	Neutral	0.356
BRCA1	P38398-1.2	V8H	Neutral	0.172
BRCA1	P38398-1.2	V8I	Neutral	0.026
BRCA1	P38398-1.2	V8K	Neutral	0.171
BRCA1	P38398-1.2	V8L	Neutral	0.053
BRCA1	P38398-1.2	V8M	Neutral	0.054
BRCA1	P38398-1.2	V8N	Neutral	0.158
BRCA1	P38398-1.2	V8P	Neutral	0.133
BRCA1	P38398-1.2	V8Q	Neutral	0.116
BRCA1	P38398-1.2	V8R	Neutral	0.284
BRCA1	P38398-1.2	V8S	Neutral	0.18
BRCA1	P38398-1.2	V8T	Neutral	0.064
BRCA1	P38398-1.2	V8W	Neutral	0.362
BRCA1	P38398-1.2	V8Y	Neutral	0.146
BRCA1	P38398-1.2	E9A	Neutral	0.306
BRCA1	P38398-1.2	E9C	Neutral	0.459
BRCA1	P38398-1.2	E9D	Neutral	0.081
BRCA1	P38398-1.2	E9F	Neutral	0.383
BRCA1	P38398-1.2	E9G	Neutral	0.493
BRCA1	P38398-1.2	E9H	Neutral	0.129
BRCA1	P38398-1.2	E9I	Neutral	0.327
BRCA1	P38398-1.2	E9K	Neutral	0.131
BRCA1	P38398-1.2	E9L	Neutral	0.328
BRCA1	P38398-1.2	E9M	Neutral	0.255
BRCA1	P38398-1.2	E9N	Neutral	0.141
BRCA1	P38398-1.2	E9P	Neutral	0.208
BRCA1	P38398-1.2	E9Q	Neutral	0.062
BRCA1	P38398-1.2	E9R	Neutral	0.224
BRCA1	P38398-1.2	E9S	Neutral	0.212
BRCA1	P38398-1.2	E9T	Neutral	0.198
BRCA1	P38398-1.2	E9V	Neutral	0.211
BRCA1	P38398-1.2	E9W	Pathogenic	0.534
BRCA1	P38398-1.2	E9Y	Neutral	0.334
BRCA1	P38398-1.2	E10A	Pathogenic	0.602
BRCA1	P38398-1.2	E10C	Pathogenic	0.745
BRCA1	P38398-1.2	E10D	Neutral	0.232
BRCA1	P38398-1.2	E10F	Pathogenic	0.681
BRCA1	P38398-1.2	E10G	Pathogenic	0.769
BRCA1	P38398-1.2	E10H	Neutral	0.336
BRCA1	P38398-1.2	E10I	Pathogenic	0.625
BRCA1	P38398-1.2	E10K	Neutral	0.341
BRCA1	P38398-1.2	E10L	Pathogenic	0.626
BRCA1	P38398-1.2	E10M	Pathogenic	0.54
BRCA1	P38398-1.2	E10N	Neutral	0.359
BRCA1	P38398-1.2	E10P	Neutral	0.474
BRCA1	P38398-1.2	E10Q	Neutral	0.184
BRCA1	P38398-1.2	E10R	Neutral	0.498
BRCA1	P38398-1.2	E10S	Neutral	0.481
BRCA1	P38398-1.2	E10T	Neutral	0.459
BRCA1	P38398-1.2	E10V	Neutral	0.479
BRCA1	P38398-1.2	E10W	Pathogenic	0.797
BRCA1	P38398-1.2	E10Y	Pathogenic	0.632
BRCA1	P38398-1.2	V11A	Pathogenic	0.597
BRCA1	P38398-1.2	V11C	Pathogenic	0.586
BRCA1	P38398-1.2	V11D	Pathogenic	0.717
BRCA1	P38398-1.2	V11E	Pathogenic	0.586
BRCA1	P38398-1.2	V11F	Pathogenic	0.643
BRCA1	P38398-1.2	V11G	Pathogenic	0.87
BRCA1	P38398-1.2	V11H	Pathogenic	0.716
BRCA1	P38398-1.2	V11I	Neutral	0.247
BRCA1	P38398-1.2	V11K	Pathogenic	0.715
BRCA1	P38398-1.2	V11L	Neutral	0.405
BRCA1	P38398-1.2	V11M	Neutral	0.407
BRCA1	P38398-1.2	V11N	Pathogenic	0.695
BRCA1	P38398-1.2	V11P	Pathogenic	0.65
BRCA1	P38398-1.2	V11Q	Pathogenic	0.615
BRCA1	P38398-1.2	V11R	Pathogenic	0.828
BRCA1	P38398-1.2	V11S	Pathogenic	0.727
BRCA1	P38398-1.2	V11T	Neutral	0.454
BRCA1	P38398-1.2	V11W	Pathogenic	0.873
BRCA1	P38398-1.2	V11Y	Pathogenic	0.674
BRCA1	P38398-1.2	Q12A	Neutral	0.295
BRCA1	P38398-1.2	Q12C	Neutral	0.359
BRCA1	P38398-1.2	Q12D	Neutral	0.146
BRCA1	P38398-1.2	Q12E	Neutral	0.052
BRCA1	P38398-1.2	Q12F	Neutral	0.321
BRCA1	P38398-1.2	Q12G	Neutral	0.48
BRCA1	P38398-1.2	Q12H	Neutral	0.101
BRCA1	P38398-1.2	Q12I	Neutral	0.27
BRCA1	P38398-1.2	Q12K	Neutral	0.101
BRCA1	P38398-1.2	Q12L	Neutral	0.205
BRCA1	P38398-1.2	Q12M	Neutral	0.112
BRCA1	P38398-1.2	Q12N	Neutral	0.133
BRCA1	P38398-1.2	Q12P	Neutral	0.199
BRCA1	P38398-1.2	Q12R	Neutral	0.131
BRCA1	P38398-1.2	Q12S	Neutral	0.204
BRCA1	P38398-1.2	Q12T	Neutral	0.19
BRCA1	P38398-1.2	Q12V	Neutral	0.203
BRCA1	P38398-1.2	Q12W	Neutral	0.378
BRCA1	P38398-1.2	Q12Y	Neutral	0.21
BRCA1	P38398-1.2	N13A	Neutral	0.42
BRCA1	P38398-1.2	N13C	Neutral	0.403
BRCA1	P38398-1.2	N13D	Neutral	0.126
BRCA1	P38398-1.2	N13E	Neutral	0.2
BRCA1	P38398-1.2	N13F	Pathogenic	0.559
BRCA1	P38398-1.2	N13G	Neutral	0.349
BRCA1	P38398-1.2	N13H	Neutral	0.173
BRCA1	P38398-1.2	N13I	Neutral	0.498
BRCA1	P38398-1.2	N13K	Neutral	0.306
BRCA1	P38398-1.2	N13L	Neutral	0.498
BRCA1	P38398-1.2	N13M	Neutral	0.411
BRCA1	P38398-1.2	N13P	Neutral	0.301
BRCA1	P38398-1.2	N13Q	Neutral	0.217
BRCA1	P38398-1.2	N13R	Neutral	0.371
BRCA1	P38398-1.2	N13S	Neutral	0.176
BRCA1	P38398-1.2	N13T	Neutral	0.164
BRCA1	P38398-1.2	N13V	Neutral	0.397
BRCA1	P38398-1.2	N13W	Pathogenic	0.771
BRCA1	P38398-1.2	N13Y	Pathogenic	0.505
BRCA1	P38398-1.2	V14A	Pathogenic	0.504
BRCA1	P38398-1.2	V14C	Neutral	0.493
BRCA1	P38398-1.2	V14D	Pathogenic	0.636
BRCA1	P38398-1.2	V14E	Neutral	0.493
BRCA1	P38398-1.2	V14F	Pathogenic	0.552
BRCA1	P38398-1.2	V14G	Pathogenic	0.821
BRCA1	P38398-1.2	V14H	Pathogenic	0.634
BRCA1	P38398-1.2	V14I	Neutral	0.184
BRCA1	P38398-1.2	V14K	Pathogenic	0.633
BRCA1	P38398-1.2	V14L	Neutral	0.319
BRCA1	P38398-1.2	V14M	Neutral	0.321
BRCA1	P38398-1.2	V14N	Pathogenic	0.61
BRCA1	P38398-1.2	V14P	Pathogenic	0.56
BRCA1	P38398-1.2	V14Q	Pathogenic	0.523
BRCA1	P38398-1.2	V14R	Pathogenic	0.768
BRCA1	P38398-1.2	V14S	Pathogenic	0.647
BRCA1	P38398-1.2	V14T	Neutral	0.363
BRCA1	P38398-1.2	V14W	Pathogenic	0.825
BRCA1	P38398-1.2	V14Y	Pathogenic	0.587
BRCA1	P38398-1.2	I15A	Neutral	0.312
BRCA1	P38398-1.2	I15C	Neutral	0.232
BRCA1	P38398-1.2	I15D	Neutral	0.351
BRCA1	P38398-1.2	I15E	Neutral	0.266
BRCA1	P38398-1.2	I15F	Neutral	0.105
BRCA1	P38398-1.2	I15G	Pathogenic	0.672
BRCA1	P38398-1.2	I15H	Neutral	0.232
BRCA1	P38398-1.2	I15K	Neutral	0.248
BRCA1	P38398-1.2	I15L	Neutral	0.042
BRCA1	P38398-1.2	I15M	Neutral	0.059
BRCA1	P38398-1.2	I15N	Neutral	0.327
BRCA1	P38398-1.2	I15P	Neutral	0.362
BRCA1	P38398-1.2	I15Q	Neutral	0.247
BRCA1	P38398-1.2	I15R	Neutral	0.306
BRCA1	P38398-1.2	I15S	Neutral	0.362
BRCA1	P38398-1.2	I15T	Neutral	0.203
BRCA1	P38398-1.2	I15V	Neutral	0.044
BRCA1	P38398-1.2	I15W	Neutral	0.391
BRCA1	P38398-1.2	I15Y	Neutral	0.159
BRCA1	P38398-1.2	N16A	Neutral	0.192
BRCA1	P38398-1.2	N16C	Neutral	0.181
BRCA1	P38398-1.2	N16D	Neutral	0.045
BRCA1	P38398-1.2	N16E	Neutral	0.075
BRCA1	P38398-1.2	N16F	Neutral	0.293
BRCA1	P38398-1.2	N16G	Neutral	0.149
BRCA1	P38398-1.2	N16H	Neutral	0.064
BRCA1	P38398-1.2	N16I	Neutral	0.245
BRCA1	P38398-1.2	N16K	Neutral	0.126
BRCA1	P38398-1.2	N16L	Neutral	0.245
BRCA1	P38398-1.2	N16M	Neutral	0.186
BRCA1	P38398-1.2	N16P	Neutral	0.124
BRCA1	P38398-1.2	N16Q	Neutral	0.083
BRCA1	P38398-1.2	N16R	Neutral	0.162
BRCA1	P38398-1.2	N16S	Neutral	0.065
BRCA1	P38398-1.2	N16T	Neutral	0.06
BRCA1	P38398-1.2	N16V	Neutral	0.177
BRCA1	P38398-1.2	N16W	Pathogenic	0.524
BRCA1	P38398-1.2	N16Y	Neutral	0.25
BRCA1	P38398-1.2	A17C	Neutral	0.3
BRCA1	P38398-1.2	A17D	Neutral	0.496
BRCA1	P38398-1.2	A17E	Pathogenic	0.506
BRCA1	P38398-1.2	A17F	Pathogenic	0.722
BRCA1	P38398-1.2	A17G	Neutral	0.302
BRCA1	P38398-1.2	A17H	Pathogenic	0.646
BRCA1	P38398-1.2	A17I	Pathogenic	0.586
BRCA1	P38398-1.2	A17K	Pathogenic	0.644
BRCA1	P38398-1.2	A17L	Pathogenic	0.586
BRCA1	P38398-1.2	A17M	Pathogenic	0.588
BRCA1	P38398-1.2	A17N	Pathogenic	0.525
BRCA1	P38398-1.2	A17P	Neutral	0.404
BRCA1	P38398-1.2	A17Q	Pathogenic	0.535
BRCA1	P38398-1.2	A17R	Pathogenic	0.707
BRCA1	P38398-1.2	A17S	Neutral	0.183
BRCA1	P38398-1.2	A17T	Neutral	0.336
BRCA1	P38398-1.2	A17V	Neutral	0.394
BRCA1	P38398-1.2	A17W	Pathogenic	0.873
BRCA1	P38398-1.2	A17Y	Pathogenic	0.751
BRCA1	P38398-1.2	M18A	Pathogenic	0.879
BRCA1	P38398-1.2	M18C	Pathogenic	0.828
BRCA1	P38398-1.2	M18D	Pathogenic	0.896
BRCA1	P38398-1.2	M18E	Pathogenic	0.801
BRCA1	P38398-1.2	M18F	Pathogenic	0.646
BRCA1	P38398-1.2	M18G	Pathogenic	0.958
BRCA1	P38398-1.2	M18H	Pathogenic	0.77
BRCA1	P38398-1.2	M18I	Neutral	0.498
BRCA1	P38398-1.2	M18K	Pathogenic	0.718
BRCA1	P38398-1.2	M18L	Neutral	0.408
BRCA1	P38398-1.2	M18N	Pathogenic	0.843
BRCA1	P38398-1.2	M18P	Pathogenic	0.863
BRCA1	P38398-1.2	M18Q	Pathogenic	0.637
BRCA1	P38398-1.2	M18R	Pathogenic	0.772
BRCA1	P38398-1.2	M18S	Pathogenic	0.863
BRCA1	P38398-1.2	M18T	Pathogenic	0.802
BRCA1	P38398-1.2	M18V	Pathogenic	0.605
BRCA1	P38398-1.2	M18W	Pathogenic	0.829
BRCA1	P38398-1.2	M18Y	Pathogenic	0.751
BRCA1	P38398-1.2	Q19A	Pathogenic	0.659
BRCA1	P38398-1.2	Q19C	Pathogenic	0.722
BRCA1	P38398-1.2	Q19D	Neutral	0.441
BRCA1	P38398-1.2	Q19E	Neutral	0.204
BRCA1	P38398-1.2	Q19F	Pathogenic	0.686
BRCA1	P38398-1.2	Q19G	Pathogenic	0.81
BRCA1	P38398-1.2	Q19H	Neutral	0.342
BRCA1	P38398-1.2	Q19I	Pathogenic	0.631
BRCA1	P38398-1.2	Q19K	Neutral	0.343
BRCA1	P38398-1.2	Q19L	Pathogenic	0.544
BRCA1	P38398-1.2	Q19M	Neutral	0.367
BRCA1	P38398-1.2	Q19N	Neutral	0.415
BRCA1	P38398-1.2	Q19P	Pathogenic	0.535
BRCA1	P38398-1.2	Q19R	Neutral	0.411
BRCA1	P38398-1.2	Q19S	Pathogenic	0.542
BRCA1	P38398-1.2	Q19T	Pathogenic	0.521
BRCA1	P38398-1.2	Q19V	Pathogenic	0.541
BRCA1	P38398-1.2	Q19W	Pathogenic	0.737
BRCA1	P38398-1.2	Q19Y	Pathogenic	0.551
BRCA1	P38398-1.2	K20A	Pathogenic	0.791
BRCA1	P38398-1.2	K20C	Pathogenic	0.835
BRCA1	P38398-1.2	K20D	Pathogenic	0.694
BRCA1	P38398-1.2	K20E	Neutral	0.422
BRCA1	P38398-1.2	K20F	Pathogenic	0.627
BRCA1	P38398-1.2	K20G	Pathogenic	0.893
BRCA1	P38398-1.2	K20H	Pathogenic	0.55
BRCA1	P38398-1.2	K20I	Pathogenic	0.682
BRCA1	P38398-1.2	K20L	Pathogenic	0.599
BRCA1	P38398-1.2	K20M	Pathogenic	0.511
BRCA1	P38398-1.2	K20N	Pathogenic	0.584
BRCA1	P38398-1.2	K20P	Pathogenic	0.692
BRCA1	P38398-1.2	K20Q	Neutral	0.394
BRCA1	P38398-1.2	K20R	Neutral	0.277
BRCA1	P38398-1.2	K20S	Pathogenic	0.698
BRCA1	P38398-1.2	K20T	Pathogenic	0.68
BRCA1	P38398-1.2	K20V	Pathogenic	0.697
BRCA1	P38398-1.2	K20W	Pathogenic	0.756
BRCA1	P38398-1.2	K20Y	Pathogenic	0.575
BRCA1	P38398-1.2	I21A	Pathogenic	0.691
BRCA1	P38398-1.2	I21C	Pathogenic	0.598
BRCA1	P38398-1.2	I21D	Pathogenic	0.727
BRCA1	P38398-1.2	I21E	Pathogenic	0.641
BRCA1	P38398-1.2	I21F	Neutral	0.365
BRCA1	P38398-1.2	I21G	Pathogenic	0.91
BRCA1	P38398-1.2	I21H	Pathogenic	0.598
BRCA1	P38398-1.2	I21K	Pathogenic	0.619
BRCA1	P38398-1.2	I21L	Neutral	0.178
BRCA1	P38398-1.2	I21M	Neutral	0.237
BRCA1	P38398-1.2	I21N	Pathogenic	0.705
BRCA1	P38398-1.2	I21P	Pathogenic	0.737
BRCA1	P38398-1.2	I21Q	Pathogenic	0.617
BRCA1	P38398-1.2	I21R	Pathogenic	0.684
BRCA1	P38398-1.2	I21S	Pathogenic	0.737
BRCA1	P38398-1.2	I21T	Pathogenic	0.556
BRCA1	P38398-1.2	I21V	Neutral	0.186
BRCA1	P38398-1.2	I21W	Pathogenic	0.76
BRCA1	P38398-1.2	I21Y	Neutral	0.482
BRCA1	P38398-1.2	L22A	Pathogenic	0.729
BRCA1	P38398-1.2	L22C	Pathogenic	0.641
BRCA1	P38398-1.2	L22D	Pathogenic	0.822
BRCA1	P38398-1.2	L22E	Pathogenic	0.683
BRCA1	P38398-1.2	L22F	Neutral	0.409
BRCA1	P38398-1.2	L22G	Pathogenic	0.924
BRCA1	P38398-1.2	L22H	Pathogenic	0.642
BRCA1	P38398-1.2	L22I	Neutral	0.207
BRCA1	P38398-1.2	L22K	Pathogenic	0.576
BRCA1	P38398-1.2	L22M	Neutral	0.206
BRCA1	P38398-1.2	L22N	Pathogenic	0.742
BRCA1	P38398-1.2	L22P	Pathogenic	0.771
BRCA1	P38398-1.2	L22Q	Pathogenic	0.575
BRCA1	P38398-1.2	L22R	Pathogenic	0.645
BRCA1	P38398-1.2	L22S	Pathogenic	0.771
BRCA1	P38398-1.2	L22T	Pathogenic	0.602
BRCA1	P38398-1.2	L22V	Neutral	0.363
BRCA1	P38398-1.2	L22W	Pathogenic	0.725
BRCA1	P38398-1.2	L22Y	Pathogenic	0.529
BRCA1	P38398-1.2	E23A	Pathogenic	0.639
BRCA1	P38398-1.2	E23C	Pathogenic	0.773
BRCA1	P38398-1.2	E23D	Neutral	0.261
BRCA1	P38398-1.2	E23F	Pathogenic	0.714
BRCA1	P38398-1.2	E23G	Pathogenic	0.796
BRCA1	P38398-1.2	E23H	Neutral	0.372
BRCA1	P38398-1.2	E23I	Pathogenic	0.662
BRCA1	P38398-1.2	E23K	Neutral	0.377
BRCA1	P38398-1.2	E23L	Pathogenic	0.662
BRCA1	P38398-1.2	E23M	Pathogenic	0.579
BRCA1	P38398-1.2	E23N	Neutral	0.397
BRCA1	P38398-1.2	E23P	Pathogenic	0.513
BRCA1	P38398-1.2	E23Q	Neutral	0.209
BRCA1	P38398-1.2	E23R	Pathogenic	0.538
BRCA1	P38398-1.2	E23S	Pathogenic	0.52
BRCA1	P38398-1.2	E23T	Neutral	0.499
BRCA1	P38398-1.2	E23V	Pathogenic	0.518
BRCA1	P38398-1.2	E23W	Pathogenic	0.822
BRCA1	P38398-1.2	E23Y	Pathogenic	0.668
BRCA1	P38398-1.2	C24A	Pathogenic	0.567
BRCA1	P38398-1.2	C24D	Pathogenic	0.737
BRCA1	P38398-1.2	C24E	Pathogenic	0.858
BRCA1	P38398-1.2	C24F	Pathogenic	0.841
BRCA1	P38398-1.2	C24G	Pathogenic	0.856
BRCA1	P38398-1.2	C24H	Pathogenic	0.839
BRCA1	P38398-1.2	C24I	Pathogenic	0.742
BRCA1	P38398-1.2	C24K	Pathogenic	0.881
BRCA1	P38398-1.2	C24L	Pathogenic	0.742
BRCA1	P38398-1.2	C24M	Pathogenic	0.744
BRCA1	P38398-1.2	C24N	Pathogenic	0.759
BRCA1	P38398-1.2	C24P	Pathogenic	0.738
BRCA1	P38398-1.2	C24Q	Pathogenic	0.825
BRCA1	P38398-1.2	C24R	Pathogenic	0.908
BRCA1	P38398-1.2	C24S	Pathogenic	0.621
BRCA1	P38398-1.2	C24T	Pathogenic	0.591
BRCA1	P38398-1.2	C24V	Pathogenic	0.656
BRCA1	P38398-1.2	C24W	Pathogenic	0.907
BRCA1	P38398-1.2	C24Y	Pathogenic	0.86
BRCA1	P38398-1.2	P25A	Pathogenic	0.571
BRCA1	P38398-1.2	P25C	Pathogenic	0.645
BRCA1	P38398-1.2	P25D	Neutral	0.444
BRCA1	P38398-1.2	P25E	Pathogenic	0.545
BRCA1	P38398-1.2	P25F	Pathogenic	0.865
BRCA1	P38398-1.2	P25G	Pathogenic	0.744
BRCA1	P38398-1.2	P25H	Pathogenic	0.681
BRCA1	P38398-1.2	P25I	Pathogenic	0.777
BRCA1	P38398-1.2	P25K	Pathogenic	0.679
BRCA1	P38398-1.2	P25L	Pathogenic	0.777
BRCA1	P38398-1.2	P25M	Pathogenic	0.709
BRCA1	P38398-1.2	P25N	Pathogenic	0.563
BRCA1	P38398-1.2	P25Q	Pathogenic	0.574
BRCA1	P38398-1.2	P25R	Pathogenic	0.803
BRCA1	P38398-1.2	P25S	Pathogenic	0.537
BRCA1	P38398-1.2	P25T	Neutral	0.46
BRCA1	P38398-1.2	P25V	Pathogenic	0.616
BRCA1	P38398-1.2	P25W	Pathogenic	0.922
BRCA1	P38398-1.2	P25Y	Pathogenic	0.837
BRCA1	P38398-1.2	I26A	Pathogenic	0.759
BRCA1	P38398-1.2	I26C	Pathogenic	0.677
BRCA1	P38398-1.2	I26D	Pathogenic	0.789
BRCA1	P38398-1.2	I26E	Pathogenic	0.716
BRCA1	P38398-1.2	I26F	Neutral	0.448
BRCA1	P38398-1.2	I26G	Pathogenic	0.934
BRCA1	P38398-1.2	I26H	Pathogenic	0.677
BRCA1	P38398-1.2	I26K	Pathogenic	0.696
BRCA1	P38398-1.2	I26L	Neutral	0.234
BRCA1	P38398-1.2	I26M	Neutral	0.304
BRCA1	P38398-1.2	I26N	Pathogenic	0.771
BRCA1	P38398-1.2	I26P	Pathogenic	0.798
BRCA1	P38398-1.2	I26Q	Pathogenic	0.694
BRCA1	P38398-1.2	I26R	Pathogenic	0.753
BRCA1	P38398-1.2	I26S	Pathogenic	0.798
BRCA1	P38398-1.2	I26T	Pathogenic	0.638
BRCA1	P38398-1.2	I26V	Neutral	0.243
BRCA1	P38398-1.2	I26W	Pathogenic	0.817
BRCA1	P38398-1.2	I26Y	Pathogenic	0.567
BRCA1	P38398-1.2	C27A	Pathogenic	0.637
BRCA1	P38398-1.2	C27D	Pathogenic	0.79
BRCA1	P38398-1.2	C27E	Pathogenic	0.89
BRCA1	P38398-1.2	C27F	Pathogenic	0.876
BRCA1	P38398-1.2	C27G	Pathogenic	0.888
BRCA1	P38398-1.2	C27H	Pathogenic	0.874
BRCA1	P38398-1.2	C27I	Pathogenic	0.793
BRCA1	P38398-1.2	C27K	Pathogenic	0.909
BRCA1	P38398-1.2	C27L	Pathogenic	0.794
BRCA1	P38398-1.2	C27M	Pathogenic	0.795
BRCA1	P38398-1.2	C27N	Pathogenic	0.808
BRCA1	P38398-1.2	C27P	Pathogenic	0.791
BRCA1	P38398-1.2	C27Q	Pathogenic	0.863
BRCA1	P38398-1.2	C27R	Pathogenic	0.93
BRCA1	P38398-1.2	C27S	Pathogenic	0.687
BRCA1	P38398-1.2	C27T	Pathogenic	0.659
BRCA1	P38398-1.2	C27V	Pathogenic	0.718
BRCA1	P38398-1.2	C27W	Pathogenic	0.929
BRCA1	P38398-1.2	C27Y	Pathogenic	0.891
BRCA1	P38398-1.2	L28A	Pathogenic	0.803
BRCA1	P38398-1.2	L28C	Pathogenic	0.731
BRCA1	P38398-1.2	L28D	Pathogenic	0.875
BRCA1	P38398-1.2	L28E	Pathogenic	0.766
BRCA1	P38398-1.2	L28F	Pathogenic	0.512
BRCA1	P38398-1.2	L28G	Pathogenic	0.949
BRCA1	P38398-1.2	L28H	Pathogenic	0.731
BRCA1	P38398-1.2	L28I	Neutral	0.284
BRCA1	P38398-1.2	L28K	Pathogenic	0.674
BRCA1	P38398-1.2	L28M	Neutral	0.282
BRCA1	P38398-1.2	L28N	Pathogenic	0.814
BRCA1	P38398-1.2	L28P	Pathogenic	0.836
BRCA1	P38398-1.2	L28Q	Pathogenic	0.672
BRCA1	P38398-1.2	L28R	Pathogenic	0.734
BRCA1	P38398-1.2	L28S	Pathogenic	0.836
BRCA1	P38398-1.2	L28T	Pathogenic	0.696
BRCA1	P38398-1.2	L28V	Neutral	0.463
BRCA1	P38398-1.2	L28W	Pathogenic	0.8
BRCA1	P38398-1.2	L28Y	Pathogenic	0.63
BRCA1	P38398-1.2	E29A	Pathogenic	0.657
BRCA1	P38398-1.2	E29C	Pathogenic	0.787
BRCA1	P38398-1.2	E29D	Neutral	0.277
BRCA1	P38398-1.2	E29F	Pathogenic	0.73
BRCA1	P38398-1.2	E29G	Pathogenic	0.809
BRCA1	P38398-1.2	E29H	Neutral	0.391
BRCA1	P38398-1.2	E29I	Pathogenic	0.679
BRCA1	P38398-1.2	E29K	Neutral	0.396
BRCA1	P38398-1.2	E29L	Pathogenic	0.68
BRCA1	P38398-1.2	E29M	Pathogenic	0.598
BRCA1	P38398-1.2	E29N	Neutral	0.416
BRCA1	P38398-1.2	E29P	Pathogenic	0.533
BRCA1	P38398-1.2	E29Q	Neutral	0.222
BRCA1	P38398-1.2	E29R	Pathogenic	0.557
BRCA1	P38398-1.2	E29S	Pathogenic	0.54
BRCA1	P38398-1.2	E29T	Pathogenic	0.518
BRCA1	P38398-1.2	E29V	Pathogenic	0.538
BRCA1	P38398-1.2	E29W	Pathogenic	0.833
BRCA1	P38398-1.2	E29Y	Pathogenic	0.686
BRCA1	P38398-1.2	L30A	Pathogenic	0.804
BRCA1	P38398-1.2	L30C	Pathogenic	0.731
BRCA1	P38398-1.2	L30D	Pathogenic	0.875
BRCA1	P38398-1.2	L30E	Pathogenic	0.766
BRCA1	P38398-1.2	L30F	Pathogenic	0.513
BRCA1	P38398-1.2	L30G	Pathogenic	0.949
BRCA1	P38398-1.2	L30H	Pathogenic	0.732
BRCA1	P38398-1.2	L30I	Neutral	0.285
BRCA1	P38398-1.2	L30K	Pathogenic	0.674
BRCA1	P38398-1.2	L30M	Neutral	0.283
BRCA1	P38398-1.2	L30N	Pathogenic	0.814
BRCA1	P38398-1.2	L30P	Pathogenic	0.837
BRCA1	P38398-1.2	L30Q	Pathogenic	0.673
BRCA1	P38398-1.2	L30R	Pathogenic	0.734
BRCA1	P38398-1.2	L30S	Pathogenic	0.837
BRCA1	P38398-1.2	L30T	Pathogenic	0.697
BRCA1	P38398-1.2	L30V	Neutral	0.464
BRCA1	P38398-1.2	L30W	Pathogenic	0.801
BRCA1	P38398-1.2	L30Y	Pathogenic	0.631
BRCA1	P38398-1.2	I31A	Pathogenic	0.817
BRCA1	P38398-1.2	I31C	Pathogenic	0.747
BRCA1	P38398-1.2	I31D	Pathogenic	0.841
BRCA1	P38398-1.2	I31E	Pathogenic	0.781
BRCA1	P38398-1.2	I31F	Pathogenic	0.534
BRCA1	P38398-1.2	I31G	Pathogenic	0.953
BRCA1	P38398-1.2	I31H	Pathogenic	0.747
BRCA1	P38398-1.2	I31K	Pathogenic	0.764
BRCA1	P38398-1.2	I31L	Neutral	0.302
BRCA1	P38398-1.2	I31M	Neutral	0.382
BRCA1	P38398-1.2	I31N	Pathogenic	0.826
BRCA1	P38398-1.2	I31P	Pathogenic	0.848
BRCA1	P38398-1.2	I31Q	Pathogenic	0.763
BRCA1	P38398-1.2	I31R	Pathogenic	0.812
BRCA1	P38398-1.2	I31S	Pathogenic	0.848
BRCA1	P38398-1.2	I31T	Pathogenic	0.714
BRCA1	P38398-1.2	I31V	Neutral	0.312
BRCA1	P38398-1.2	I31W	Pathogenic	0.863
BRCA1	P38398-1.2	I31Y	Pathogenic	0.65
BRCA1	P38398-1.2	K32A	Pathogenic	0.722
BRCA1	P38398-1.2	K32C	Pathogenic	0.777
BRCA1	P38398-1.2	K32D	Pathogenic	0.608
BRCA1	P38398-1.2	K32E	Neutral	0.334
BRCA1	P38398-1.2	K32F	Pathogenic	0.535
BRCA1	P38398-1.2	K32G	Pathogenic	0.851
BRCA1	P38398-1.2	K32H	Neutral	0.456
BRCA1	P38398-1.2	K32I	Pathogenic	0.595
BRCA1	P38398-1.2	K32L	Pathogenic	0.506
BRCA1	P38398-1.2	K32M	Neutral	0.418
BRCA1	P38398-1.2	K32N	Neutral	0.49
BRCA1	P38398-1.2	K32P	Pathogenic	0.607
BRCA1	P38398-1.2	K32Q	Neutral	0.308
BRCA1	P38398-1.2	K32R	Neutral	0.208
BRCA1	P38398-1.2	K32S	Pathogenic	0.613
BRCA1	P38398-1.2	K32T	Pathogenic	0.593
BRCA1	P38398-1.2	K32V	Pathogenic	0.612
BRCA1	P38398-1.2	K32W	Pathogenic	0.68
BRCA1	P38398-1.2	K32Y	Neutral	0.482
BRCA1	P38398-1.2	E33A	Pathogenic	0.656
BRCA1	P38398-1.2	E33C	Pathogenic	0.786
BRCA1	P38398-1.2	E33D	Neutral	0.276
BRCA1	P38398-1.2	E33F	Pathogenic	0.729
BRCA1	P38398-1.2	E33G	Pathogenic	0.808
BRCA1	P38398-1.2	E33H	Neutral	0.39
BRCA1	P38398-1.2	E33I	Pathogenic	0.678
BRCA1	P38398-1.2	E33K	Neutral	0.395
BRCA1	P38398-1.2	E33L	Pathogenic	0.678
BRCA1	P38398-1.2	E33M	Pathogenic	0.597
BRCA1	P38398-1.2	E33N	Neutral	0.414
BRCA1	P38398-1.2	E33P	Pathogenic	0.531
BRCA1	P38398-1.2	E33Q	Neutral	0.221
BRCA1	P38398-1.2	E33R	Pathogenic	0.556
BRCA1	P38398-1.2	E33S	Pathogenic	0.538
BRCA1	P38398-1.2	E33T	Pathogenic	0.517
BRCA1	P38398-1.2	E33V	Pathogenic	0.537
BRCA1	P38398-1.2	E33W	Pathogenic	0.832
BRCA1	P38398-1.2	E33Y	Pathogenic	0.684
BRCA1	P38398-1.2	P34A	Pathogenic	0.65
BRCA1	P38398-1.2	P34C	Pathogenic	0.716
BRCA1	P38398-1.2	P34D	Pathogenic	0.527
BRCA1	P38398-1.2	P34E	Pathogenic	0.625
BRCA1	P38398-1.2	P34F	Pathogenic	0.899
BRCA1	P38398-1.2	P34G	Pathogenic	0.802
BRCA1	P38398-1.2	P34H	Pathogenic	0.748
BRCA1	P38398-1.2	P34I	Pathogenic	0.829
BRCA1	P38398-1.2	P34K	Pathogenic	0.747
BRCA1	P38398-1.2	P34L	Pathogenic	0.829
BRCA1	P38398-1.2	P34M	Pathogenic	0.773
BRCA1	P38398-1.2	P34N	Pathogenic	0.643
BRCA1	P38398-1.2	P34Q	Pathogenic	0.652
BRCA1	P38398-1.2	P34R	Pathogenic	0.85
BRCA1	P38398-1.2	P34S	Pathogenic	0.617
BRCA1	P38398-1.2	P34T	Pathogenic	0.543
BRCA1	P38398-1.2	P34V	Pathogenic	0.69
BRCA1	P38398-1.2	P34W	Pathogenic	0.943
BRCA1	P38398-1.2	P34Y	Pathogenic	0.878
BRCA1	P38398-1.2	V35A	Pathogenic	0.504
BRCA1	P38398-1.2	V35C	Neutral	0.493
BRCA1	P38398-1.2	V35D	Pathogenic	0.635
BRCA1	P38398-1.2	V35E	Neutral	0.493
BRCA1	P38398-1.2	V35F	Pathogenic	0.552
BRCA1	P38398-1.2	V35G	Pathogenic	0.821
BRCA1	P38398-1.2	V35H	Pathogenic	0.634
BRCA1	P38398-1.2	V35I	Neutral	0.184
BRCA1	P38398-1.2	V35K	Pathogenic	0.632
BRCA1	P38398-1.2	V35L	Neutral	0.318
BRCA1	P38398-1.2	V35M	Neutral	0.32
BRCA1	P38398-1.2	V35N	Pathogenic	0.61
BRCA1	P38398-1.2	V35P	Pathogenic	0.56
BRCA1	P38398-1.2	V35Q	Pathogenic	0.522
BRCA1	P38398-1.2	V35R	Pathogenic	0.767
BRCA1	P38398-1.2	V35S	Pathogenic	0.647
BRCA1	P38398-1.2	V35T	Neutral	0.363
BRCA1	P38398-1.2	V35W	Pathogenic	0.825
BRCA1	P38398-1.2	V35Y	Pathogenic	0.586
BRCA1	P38398-1.2	S36A	Neutral	0.333
BRCA1	P38398-1.2	S36C	Pathogenic	0.544
BRCA1	P38398-1.2	S36D	Neutral	0.482
BRCA1	P38398-1.2	S36E	Pathogenic	0.582
BRCA1	P38398-1.2	S36F	Pathogenic	0.834
BRCA1	P38398-1.2	S36G	Pathogenic	0.525
BRCA1	P38398-1.2	S36H	Pathogenic	0.712
BRCA1	P38398-1.2	S36I	Pathogenic	0.797
BRCA1	P38398-1.2	S36K	Pathogenic	0.711
BRCA1	P38398-1.2	S36L	Pathogenic	0.798
BRCA1	P38398-1.2	S36M	Pathogenic	0.734
BRCA1	P38398-1.2	S36N	Neutral	0.421
BRCA1	P38398-1.2	S36P	Pathogenic	0.567
BRCA1	P38398-1.2	S36Q	Pathogenic	0.611
BRCA1	P38398-1.2	S36R	Pathogenic	0.826
BRCA1	P38398-1.2	S36T	Neutral	0.406
BRCA1	P38398-1.2	S36V	Pathogenic	0.723
BRCA1	P38398-1.2	S36W	Pathogenic	0.93
BRCA1	P38398-1.2	S36Y	Pathogenic	0.854
BRCA1	P38398-1.2	T37A	Pathogenic	0.507
BRCA1	P38398-1.2	T37C	Neutral	0.489
BRCA1	P38398-1.2	T37D	Neutral	0.46
BRCA1	P38398-1.2	T37E	Pathogenic	0.538
BRCA1	P38398-1.2	T37F	Pathogenic	0.747
BRCA1	P38398-1.2	T37G	Pathogenic	0.764
BRCA1	P38398-1.2	T37H	Pathogenic	0.675
BRCA1	P38398-1.2	T37I	Pathogenic	0.616
BRCA1	P38398-1.2	T37K	Pathogenic	0.673
BRCA1	P38398-1.2	T37L	Pathogenic	0.616
BRCA1	P38398-1.2	T37M	Pathogenic	0.619
BRCA1	P38398-1.2	T37N	Neutral	0.377
BRCA1	P38398-1.2	T37P	Neutral	0.468
BRCA1	P38398-1.2	T37Q	Pathogenic	0.567
BRCA1	P38398-1.2	T37R	Pathogenic	0.733
BRCA1	P38398-1.2	T37S	Neutral	0.383
BRCA1	P38398-1.2	T37V	Neutral	0.425
BRCA1	P38398-1.2	T37W	Pathogenic	0.845
BRCA1	P38398-1.2	T37Y	Pathogenic	0.774
BRCA1	P38398-1.2	K38A	Neutral	0.339
BRCA1	P38398-1.2	K38C	Neutral	0.408
BRCA1	P38398-1.2	K38D	Neutral	0.235
BRCA1	P38398-1.2	K38E	Neutral	0.09
BRCA1	P38398-1.2	K38F	Neutral	0.186
BRCA1	P38398-1.2	K38G	Pathogenic	0.531
BRCA1	P38398-1.2	K38H	Neutral	0.142
BRCA1	P38398-1.2	K38I	Neutral	0.226
BRCA1	P38398-1.2	K38L	Neutral	0.169
BRCA1	P38398-1.2	K38M	Neutral	0.124
BRCA1	P38398-1.2	K38N	Neutral	0.16
BRCA1	P38398-1.2	K38P	Neutral	0.234
BRCA1	P38398-1.2	K38Q	Neutral	0.081
BRCA1	P38398-1.2	K38R	Neutral	0.049
BRCA1	P38398-1.2	K38S	Neutral	0.239
BRCA1	P38398-1.2	K38T	Neutral	0.224
BRCA1	P38398-1.2	K38V	Neutral	0.238
BRCA1	P38398-1.2	K38W	Neutral	0.296
BRCA1	P38398-1.2	K38Y	Neutral	0.155
BRCA1	P38398-1.2	C39A	Pathogenic	0.664
BRCA1	P38398-1.2	C39D	Pathogenic	0.808
BRCA1	P38398-1.2	C39E	Pathogenic	0.901
BRCA1	P38398-1.2	C39F	Pathogenic	0.888
BRCA1	P38398-1.2	C39G	Pathogenic	0.899
BRCA1	P38398-1.2	C39H	Pathogenic	0.887
BRCA1	P38398-1.2	C39I	Pathogenic	0.812
BRCA1	P38398-1.2	C39K	Pathogenic	0.918
BRCA1	P38398-1.2	C39L	Pathogenic	0.812
BRCA1	P38398-1.2	C39M	Pathogenic	0.814
BRCA1	P38398-1.2	C39N	Pathogenic	0.825
BRCA1	P38398-1.2	C39P	Pathogenic	0.809
BRCA1	P38398-1.2	C39Q	Pathogenic	0.877
BRCA1	P38398-1.2	C39R	Pathogenic	0.937
BRCA1	P38398-1.2	C39S	Pathogenic	0.712
BRCA1	P38398-1.2	C39T	Pathogenic	0.685
BRCA1	P38398-1.2	C39V	Pathogenic	0.741
BRCA1	P38398-1.2	C39W	Pathogenic	0.936
BRCA1	P38398-1.2	C39Y	Pathogenic	0.902
BRCA1	P38398-1.2	D40A	Pathogenic	0.671
BRCA1	P38398-1.2	D40C	Pathogenic	0.655
BRCA1	P38398-1.2	D40E	Neutral	0.297
BRCA1	P38398-1.2	D40F	Pathogenic	0.816
BRCA1	P38398-1.2	D40G	Pathogenic	0.685
BRCA1	P38398-1.2	D40H	Pathogenic	0.603
BRCA1	P38398-1.2	D40I	Pathogenic	0.777
BRCA1	P38398-1.2	D40K	Pathogenic	0.692
BRCA1	P38398-1.2	D40L	Pathogenic	0.834
BRCA1	P38398-1.2	D40M	Pathogenic	0.779
BRCA1	P38398-1.2	D40N	Neutral	0.313
BRCA1	P38398-1.2	D40P	Neutral	0.457
BRCA1	P38398-1.2	D40Q	Neutral	0.493
BRCA1	P38398-1.2	D40R	Pathogenic	0.812
BRCA1	P38398-1.2	D40S	Neutral	0.464
BRCA1	P38398-1.2	D40T	Neutral	0.465
BRCA1	P38398-1.2	D40V	Pathogenic	0.698
BRCA1	P38398-1.2	D40W	Pathogenic	0.922
BRCA1	P38398-1.2	D40Y	Pathogenic	0.838
BRCA1	P38398-1.2	H41A	Pathogenic	0.871
BRCA1	P38398-1.2	H41C	Pathogenic	0.863
BRCA1	P38398-1.2	H41D	Pathogenic	0.731
BRCA1	P38398-1.2	H41E	Pathogenic	0.559
BRCA1	P38398-1.2	H41F	Pathogenic	0.682
BRCA1	P38398-1.2	H41G	Pathogenic	0.912
BRCA1	P38398-1.2	H41I	Pathogenic	0.776
BRCA1	P38398-1.2	H41K	Pathogenic	0.684
BRCA1	P38398-1.2	H41L	Pathogenic	0.777
BRCA1	P38398-1.2	H41M	Pathogenic	0.709
BRCA1	P38398-1.2	H41N	Pathogenic	0.541
BRCA1	P38398-1.2	H41P	Pathogenic	0.801
BRCA1	P38398-1.2	H41Q	Pathogenic	0.534
BRCA1	P38398-1.2	H41R	Pathogenic	0.667
BRCA1	P38398-1.2	H41S	Pathogenic	0.804
BRCA1	P38398-1.2	H41T	Pathogenic	0.791
BRCA1	P38398-1.2	H41V	Pathogenic	0.804
BRCA1	P38398-1.2	H41W	Pathogenic	0.851
BRCA1	P38398-1.2	H41Y	Neutral	0.455
BRCA1	P38398-1.2	I42A	Pathogenic	0.761
BRCA1	P38398-1.2	I42C	Pathogenic	0.679
BRCA1	P38398-1.2	I42D	Pathogenic	0.791
BRCA1	P38398-1.2	I42E	Pathogenic	0.718
BRCA1	P38398-1.2	I42F	Neutral	0.45
BRCA1	P38398-1.2	I42G	Pathogenic	0.935
BRCA1	P38398-1.2	I42H	Pathogenic	0.679
BRCA1	P38398-1.2	I42K	Pathogenic	0.698
BRCA1	P38398-1.2	I42L	Neutral	0.236
BRCA1	P38398-1.2	I42M	Neutral	0.306
BRCA1	P38398-1.2	I42N	Pathogenic	0.773
BRCA1	P38398-1.2	I42P	Pathogenic	0.799
BRCA1	P38398-1.2	I42Q	Pathogenic	0.697
BRCA1	P38398-1.2	I42R	Pathogenic	0.755
BRCA1	P38398-1.2	I42S	Pathogenic	0.799
BRCA1	P38398-1.2	I42T	Pathogenic	0.641
BRCA1	P38398-1.2	I42V	Neutral	0.245
BRCA1	P38398-1.2	I42W	Pathogenic	0.818
BRCA1	P38398-1.2	I42Y	Pathogenic	0.57
BRCA1	P38398-1.2	F43A	Pathogenic	0.903
BRCA1	P38398-1.2	F43C	Pathogenic	0.86
BRCA1	P38398-1.2	F43D	Pathogenic	0.885
BRCA1	P38398-1.2	F43E	Pathogenic	0.838
BRCA1	P38398-1.2	F43G	Pathogenic	0.953
BRCA1	P38398-1.2	F43H	Pathogenic	0.674
BRCA1	P38398-1.2	F43I	Pathogenic	0.565
BRCA1	P38398-1.2	F43K	Pathogenic	0.742
BRCA1	P38398-1.2	F43L	Pathogenic	0.565
BRCA1	P38398-1.2	F43M	Pathogenic	0.563
BRCA1	P38398-1.2	F43N	Pathogenic	0.873
BRCA1	P38398-1.2	F43P	Pathogenic	0.921
BRCA1	P38398-1.2	F43Q	Pathogenic	0.823
BRCA1	P38398-1.2	F43R	Pathogenic	0.793
BRCA1	P38398-1.2	F43S	Pathogenic	0.89
BRCA1	P38398-1.2	F43T	Pathogenic	0.839
BRCA1	P38398-1.2	F43V	Pathogenic	0.738
BRCA1	P38398-1.2	F43W	Pathogenic	0.566
BRCA1	P38398-1.2	F43Y	Neutral	0.277
BRCA1	P38398-1.2	C44A	Pathogenic	0.609
BRCA1	P38398-1.2	C44D	Pathogenic	0.769
BRCA1	P38398-1.2	C44E	Pathogenic	0.877
BRCA1	P38398-1.2	C44F	Pathogenic	0.862
BRCA1	P38398-1.2	C44G	Pathogenic	0.875
BRCA1	P38398-1.2	C44H	Pathogenic	0.86
BRCA1	P38398-1.2	C44I	Pathogenic	0.773
BRCA1	P38398-1.2	C44K	Pathogenic	0.898
BRCA1	P38398-1.2	C44L	Pathogenic	0.773
BRCA1	P38398-1.2	C44M	Pathogenic	0.775
BRCA1	P38398-1.2	C44N	Pathogenic	0.789
BRCA1	P38398-1.2	C44P	Pathogenic	0.77
BRCA1	P38398-1.2	C44Q	Pathogenic	0.849
BRCA1	P38398-1.2	C44R	Pathogenic	0.922
BRCA1	P38398-1.2	C44S	Pathogenic	0.661
BRCA1	P38398-1.2	C44T	Pathogenic	0.631
BRCA1	P38398-1.2	C44V	Pathogenic	0.693
BRCA1	P38398-1.2	C44W	Pathogenic	0.92
BRCA1	P38398-1.2	C44Y	Pathogenic	0.879
BRCA1	P38398-1.2	K45A	Neutral	0.35
BRCA1	P38398-1.2	K45C	Neutral	0.419
BRCA1	P38398-1.2	K45D	Neutral	0.244
BRCA1	P38398-1.2	K45E	Neutral	0.094
BRCA1	P38398-1.2	K45F	Neutral	0.193
BRCA1	P38398-1.2	K45G	Pathogenic	0.543
BRCA1	P38398-1.2	K45H	Neutral	0.148
BRCA1	P38398-1.2	K45I	Neutral	0.234
BRCA1	P38398-1.2	K45L	Neutral	0.175
BRCA1	P38398-1.2	K45M	Neutral	0.13
BRCA1	P38398-1.2	K45N	Neutral	0.167
BRCA1	P38398-1.2	K45P	Neutral	0.243
BRCA1	P38398-1.2	K45Q	Neutral	0.085
BRCA1	P38398-1.2	K45R	Neutral	0.052
BRCA1	P38398-1.2	K45S	Neutral	0.248
BRCA1	P38398-1.2	K45T	Neutral	0.232
BRCA1	P38398-1.2	K45V	Neutral	0.247
BRCA1	P38398-1.2	K45W	Neutral	0.306
BRCA1	P38398-1.2	K45Y	Neutral	0.162
BRCA1	P38398-1.2	F46A	Pathogenic	0.902
BRCA1	P38398-1.2	F46C	Pathogenic	0.86
BRCA1	P38398-1.2	F46D	Pathogenic	0.884
BRCA1	P38398-1.2	F46E	Pathogenic	0.837
BRCA1	P38398-1.2	F46G	Pathogenic	0.953
BRCA1	P38398-1.2	F46H	Pathogenic	0.673
BRCA1	P38398-1.2	F46I	Pathogenic	0.564
BRCA1	P38398-1.2	F46K	Pathogenic	0.741
BRCA1	P38398-1.2	F46L	Pathogenic	0.564
BRCA1	P38398-1.2	F46M	Pathogenic	0.562
BRCA1	P38398-1.2	F46N	Pathogenic	0.873
BRCA1	P38398-1.2	F46P	Pathogenic	0.92
BRCA1	P38398-1.2	F46Q	Pathogenic	0.823
BRCA1	P38398-1.2	F46R	Pathogenic	0.793
BRCA1	P38398-1.2	F46S	Pathogenic	0.889
BRCA1	P38398-1.2	F46T	Pathogenic	0.838
BRCA1	P38398-1.2	F46V	Pathogenic	0.738
BRCA1	P38398-1.2	F46W	Pathogenic	0.565
BRCA1	P38398-1.2	F46Y	Neutral	0.277
BRCA1	P38398-1.2	C47A	Pathogenic	0.591
BRCA1	P38398-1.2	C47D	Pathogenic	0.755
BRCA1	P38398-1.2	C47E	Pathogenic	0.869
BRCA1	P38398-1.2	C47F	Pathogenic	0.853
BRCA1	P38398-1.2	C47G	Pathogenic	0.867
BRCA1	P38398-1.2	C47H	Pathogenic	0.851
BRCA1	P38398-1.2	C47I	Pathogenic	0.76
BRCA1	P38398-1.2	C47K	Pathogenic	0.891
BRCA1	P38398-1.2	C47L	Pathogenic	0.76
BRCA1	P38398-1.2	C47M	Pathogenic	0.762
BRCA1	P38398-1.2	C47N	Pathogenic	0.776
BRCA1	P38398-1.2	C47P	Pathogenic	0.757
BRCA1	P38398-1.2	C47Q	Pathogenic	0.839
BRCA1	P38398-1.2	C47R	Pathogenic	0.916
BRCA1	P38398-1.2	C47S	Pathogenic	0.644
BRCA1	P38398-1.2	C47T	Pathogenic	0.614
BRCA1	P38398-1.2	C47V	Pathogenic	0.677
BRCA1	P38398-1.2	C47W	Pathogenic	0.915
BRCA1	P38398-1.2	C47Y	Pathogenic	0.871
BRCA1	P38398-1.2	M48A	Pathogenic	0.859
BRCA1	P38398-1.2	M48C	Pathogenic	0.802
BRCA1	P38398-1.2	M48D	Pathogenic	0.879
BRCA1	P38398-1.2	M48E	Pathogenic	0.772
BRCA1	P38398-1.2	M48F	Pathogenic	0.606
BRCA1	P38398-1.2	M48G	Pathogenic	0.95
BRCA1	P38398-1.2	M48H	Pathogenic	0.738
BRCA1	P38398-1.2	M48I	Neutral	0.456
BRCA1	P38398-1.2	M48K	Pathogenic	0.682
BRCA1	P38398-1.2	M48L	Neutral	0.368
BRCA1	P38398-1.2	M48N	Pathogenic	0.819
BRCA1	P38398-1.2	M48P	Pathogenic	0.842
BRCA1	P38398-1.2	M48Q	Pathogenic	0.597
BRCA1	P38398-1.2	M48R	Pathogenic	0.741
BRCA1	P38398-1.2	M48S	Pathogenic	0.841
BRCA1	P38398-1.2	M48T	Pathogenic	0.774
BRCA1	P38398-1.2	M48V	Pathogenic	0.563
BRCA1	P38398-1.2	M48W	Pathogenic	0.803
BRCA1	P38398-1.2	M48Y	Pathogenic	0.718
BRCA1	P38398-1.2	L49A	Pathogenic	0.776
BRCA1	P38398-1.2	L49C	Pathogenic	0.697
BRCA1	P38398-1.2	L49D	Pathogenic	0.856
BRCA1	P38398-1.2	L49E	Pathogenic	0.735
BRCA1	P38398-1.2	L49F	Neutral	0.471
BRCA1	P38398-1.2	L49G	Pathogenic	0.94
BRCA1	P38398-1.2	L49H	Pathogenic	0.697
BRCA1	P38398-1.2	L49I	Neutral	0.252
BRCA1	P38398-1.2	L49K	Pathogenic	0.637
BRCA1	P38398-1.2	L49M	Neutral	0.25
BRCA1	P38398-1.2	L49N	Pathogenic	0.787
BRCA1	P38398-1.2	L49P	Pathogenic	0.813
BRCA1	P38398-1.2	L49Q	Pathogenic	0.635
BRCA1	P38398-1.2	L49R	Pathogenic	0.7
BRCA1	P38398-1.2	L49S	Pathogenic	0.813
BRCA1	P38398-1.2	L49T	Pathogenic	0.66
BRCA1	P38398-1.2	L49V	Neutral	0.423
BRCA1	P38398-1.2	L49W	Pathogenic	0.773
BRCA1	P38398-1.2	L49Y	Pathogenic	0.591
BRCA1	P38398-1.2	K50A	Pathogenic	0.796
BRCA1	P38398-1.2	K50C	Pathogenic	0.839
BRCA1	P38398-1.2	K50D	Pathogenic	0.7
BRCA1	P38398-1.2	K50E	Neutral	0.429
BRCA1	P38398-1.2	K50F	Pathogenic	0.634
BRCA1	P38398-1.2	K50G	Pathogenic	0.896
BRCA1	P38398-1.2	K50H	Pathogenic	0.557
BRCA1	P38398-1.2	K50I	Pathogenic	0.688
BRCA1	P38398-1.2	K50L	Pathogenic	0.606
BRCA1	P38398-1.2	K50M	Pathogenic	0.519
BRCA1	P38398-1.2	K50N	Pathogenic	0.591
BRCA1	P38398-1.2	K50P	Pathogenic	0.698
BRCA1	P38398-1.2	K50Q	Neutral	0.401
BRCA1	P38398-1.2	K50R	Neutral	0.283
BRCA1	P38398-1.2	K50S	Pathogenic	0.704
BRCA1	P38398-1.2	K50T	Pathogenic	0.686
BRCA1	P38398-1.2	K50V	Pathogenic	0.703
BRCA1	P38398-1.2	K50W	Pathogenic	0.761
BRCA1	P38398-1.2	K50Y	Pathogenic	0.582
BRCA1	P38398-1.2	L51A	Pathogenic	0.611
BRCA1	P38398-1.2	L51C	Pathogenic	0.511
BRCA1	P38398-1.2	L51D	Pathogenic	0.729
BRCA1	P38398-1.2	L51E	Pathogenic	0.557
BRCA1	P38398-1.2	L51F	Neutral	0.287
BRCA1	P38398-1.2	L51G	Pathogenic	0.877
BRCA1	P38398-1.2	L51H	Pathogenic	0.511
BRCA1	P38398-1.2	L51I	Neutral	0.132
BRCA1	P38398-1.2	L51K	Neutral	0.443
BRCA1	P38398-1.2	L51M	Neutral	0.132
BRCA1	P38398-1.2	L51N	Pathogenic	0.627
BRCA1	P38398-1.2	L51P	Pathogenic	0.663
BRCA1	P38398-1.2	L51Q	Neutral	0.441
BRCA1	P38398-1.2	L51R	Pathogenic	0.515
BRCA1	P38398-1.2	L51S	Pathogenic	0.663
BRCA1	P38398-1.2	L51T	Neutral	0.469
BRCA1	P38398-1.2	L51V	Neutral	0.249
BRCA1	P38398-1.2	L51W	Pathogenic	0.607
BRCA1	P38398-1.2	L51Y	Neutral	0.396
BRCA1	P38398-1.2	L52A	Pathogenic	0.798
BRCA1	P38398-1.2	L52C	Pathogenic	0.724
BRCA1	P38398-1.2	L52D	Pathogenic	0.871
BRCA1	P38398-1.2	L52E	Pathogenic	0.76
BRCA1	P38398-1.2	L52F	Pathogenic	0.504
BRCA1	P38398-1.2	L52G	Pathogenic	0.947
BRCA1	P38398-1.2	L52H	Pathogenic	0.724
BRCA1	P38398-1.2	L52I	Neutral	0.277
BRCA1	P38398-1.2	L52K	Pathogenic	0.666
BRCA1	P38398-1.2	L52M	Neutral	0.276
BRCA1	P38398-1.2	L52N	Pathogenic	0.809
BRCA1	P38398-1.2	L52P	Pathogenic	0.832
BRCA1	P38398-1.2	L52Q	Pathogenic	0.665
BRCA1	P38398-1.2	L52R	Pathogenic	0.727
BRCA1	P38398-1.2	L52S	Pathogenic	0.832
BRCA1	P38398-1.2	L52T	Pathogenic	0.689
BRCA1	P38398-1.2	L52V	Neutral	0.455
BRCA1	P38398-1.2	L52W	Pathogenic	0.795
BRCA1	P38398-1.2	L52Y	Pathogenic	0.622
BRCA1	P38398-1.2	N53A	Neutral	0.23
BRCA1	P38398-1.2	N53C	Neutral	0.217
BRCA1	P38398-1.2	N53D	Neutral	0.056
BRCA1	P38398-1.2	N53E	Neutral	0.093
BRCA1	P38398-1.2	N53F	Neutral	0.343
BRCA1	P38398-1.2	N53G	Neutral	0.181
BRCA1	P38398-1.2	N53H	Neutral	0.079
BRCA1	P38398-1.2	N53I	Neutral	0.29
BRCA1	P38398-1.2	N53K	Neutral	0.154
BRCA1	P38398-1.2	N53L	Neutral	0.29
BRCA1	P38398-1.2	N53M	Neutral	0.223
BRCA1	P38398-1.2	N53P	Neutral	0.151
BRCA1	P38398-1.2	N53Q	Neutral	0.102
BRCA1	P38398-1.2	N53R	Neutral	0.195
BRCA1	P38398-1.2	N53S	Neutral	0.081
BRCA1	P38398-1.2	N53T	Neutral	0.075
BRCA1	P38398-1.2	N53V	Neutral	0.213
BRCA1	P38398-1.2	N53W	Pathogenic	0.581
BRCA1	P38398-1.2	N53Y	Neutral	0.296
BRCA1	P38398-1.2	Q54A	Pathogenic	0.594
BRCA1	P38398-1.2	Q54C	Pathogenic	0.662
BRCA1	P38398-1.2	Q54D	Neutral	0.373
BRCA1	P38398-1.2	Q54E	Neutral	0.162
BRCA1	P38398-1.2	Q54F	Pathogenic	0.623
BRCA1	P38398-1.2	Q54G	Pathogenic	0.763
BRCA1	P38398-1.2	Q54H	Neutral	0.282
BRCA1	P38398-1.2	Q54I	Pathogenic	0.564
BRCA1	P38398-1.2	Q54K	Neutral	0.283
BRCA1	P38398-1.2	Q54L	Neutral	0.474
BRCA1	P38398-1.2	Q54M	Neutral	0.305
BRCA1	P38398-1.2	Q54N	Neutral	0.349
BRCA1	P38398-1.2	Q54P	Neutral	0.465
BRCA1	P38398-1.2	Q54R	Neutral	0.345
BRCA1	P38398-1.2	Q54S	Neutral	0.472
BRCA1	P38398-1.2	Q54T	Neutral	0.451
BRCA1	P38398-1.2	Q54V	Neutral	0.471
BRCA1	P38398-1.2	Q54W	Pathogenic	0.679
BRCA1	P38398-1.2	Q54Y	Neutral	0.481
BRCA1	P38398-1.2	K55A	Pathogenic	0.663
BRCA1	P38398-1.2	K55C	Pathogenic	0.725
BRCA1	P38398-1.2	K55D	Pathogenic	0.541
BRCA1	P38398-1.2	K55E	Neutral	0.276
BRCA1	P38398-1.2	K55F	Neutral	0.467
BRCA1	P38398-1.2	K55G	Pathogenic	0.813
BRCA1	P38398-1.2	K55H	Neutral	0.389
BRCA1	P38398-1.2	K55I	Pathogenic	0.528
BRCA1	P38398-1.2	K55L	Neutral	0.438
BRCA1	P38398-1.2	K55M	Neutral	0.353
BRCA1	P38398-1.2	K55N	Neutral	0.423
BRCA1	P38398-1.2	K55P	Pathogenic	0.54
BRCA1	P38398-1.2	K55Q	Neutral	0.253
BRCA1	P38398-1.2	K55R	Neutral	0.167
BRCA1	P38398-1.2	K55S	Pathogenic	0.547
BRCA1	P38398-1.2	K55T	Pathogenic	0.525
BRCA1	P38398-1.2	K55V	Pathogenic	0.545
BRCA1	P38398-1.2	K55W	Pathogenic	0.618
BRCA1	P38398-1.2	K55Y	Neutral	0.414
BRCA1	P38398-1.2	K56A	Pathogenic	0.642
BRCA1	P38398-1.2	K56C	Pathogenic	0.706
BRCA1	P38398-1.2	K56D	Pathogenic	0.518
BRCA1	P38398-1.2	K56E	Neutral	0.257
BRCA1	P38398-1.2	K56F	Neutral	0.443
BRCA1	P38398-1.2	K56G	Pathogenic	0.798
BRCA1	P38398-1.2	K56H	Neutral	0.367
BRCA1	P38398-1.2	K56I	Pathogenic	0.504
BRCA1	P38398-1.2	K56L	Neutral	0.414
BRCA1	P38398-1.2	K56M	Neutral	0.332
BRCA1	P38398-1.2	K56N	Neutral	0.4
BRCA1	P38398-1.2	K56P	Pathogenic	0.516
BRCA1	P38398-1.2	K56Q	Neutral	0.235
BRCA1	P38398-1.2	K56R	Neutral	0.154
BRCA1	P38398-1.2	K56S	Pathogenic	0.523
BRCA1	P38398-1.2	K56T	Pathogenic	0.502
BRCA1	P38398-1.2	K56V	Pathogenic	0.521
BRCA1	P38398-1.2	K56W	Pathogenic	0.595
BRCA1	P38398-1.2	K56Y	Neutral	0.391
BRCA1	P38398-1.2	G57A	Pathogenic	0.621
BRCA1	P38398-1.2	G57C	Pathogenic	0.88
BRCA1	P38398-1.2	G57D	Pathogenic	0.8
BRCA1	P38398-1.2	G57E	Pathogenic	0.896
BRCA1	P38398-1.2	G57F	Pathogenic	0.956
BRCA1	P38398-1.2	G57H	Pathogenic	0.914
BRCA1	P38398-1.2	G57I	Pathogenic	0.96
BRCA1	P38398-1.2	G57K	Pathogenic	0.938
BRCA1	P38398-1.2	G57L	Pathogenic	0.96
BRCA1	P38398-1.2	G57M	Pathogenic	0.945
BRCA1	P38398-1.2	G57N	Pathogenic	0.757
BRCA1	P38398-1.2	G57P	Pathogenic	0.849
BRCA1	P38398-1.2	G57Q	Pathogenic	0.906
BRCA1	P38398-1.2	G57R	Pathogenic	0.953
BRCA1	P38398-1.2	G57S	Pathogenic	0.653
BRCA1	P38398-1.2	G57T	Pathogenic	0.858
BRCA1	P38398-1.2	G57V	Pathogenic	0.918
BRCA1	P38398-1.2	G57W	Pathogenic	0.965
BRCA1	P38398-1.2	G57Y	Pathogenic	0.962
BRCA1	P38398-1.2	P58A	Pathogenic	0.536
BRCA1	P38398-1.2	P58C	Pathogenic	0.611
BRCA1	P38398-1.2	P58D	Neutral	0.409
BRCA1	P38398-1.2	P58E	Pathogenic	0.509
BRCA1	P38398-1.2	P58F	Pathogenic	0.847
BRCA1	P38398-1.2	P58G	Pathogenic	0.716
BRCA1	P38398-1.2	P58H	Pathogenic	0.649
BRCA1	P38398-1.2	P58I	Pathogenic	0.751
BRCA1	P38398-1.2	P58K	Pathogenic	0.647
BRCA1	P38398-1.2	P58L	Pathogenic	0.751
BRCA1	P38398-1.2	P58M	Pathogenic	0.679
BRCA1	P38398-1.2	P58N	Pathogenic	0.528
BRCA1	P38398-1.2	P58Q	Pathogenic	0.539
BRCA1	P38398-1.2	P58R	Pathogenic	0.779
BRCA1	P38398-1.2	P58S	Pathogenic	0.501
BRCA1	P38398-1.2	P58T	Neutral	0.425
BRCA1	P38398-1.2	P58V	Pathogenic	0.581
BRCA1	P38398-1.2	P58W	Pathogenic	0.911
BRCA1	P38398-1.2	P58Y	Pathogenic	0.817
BRCA1	P38398-1.2	S59A	Neutral	0.144
BRCA1	P38398-1.2	S59C	Neutral	0.287
BRCA1	P38398-1.2	S59D	Neutral	0.239
BRCA1	P38398-1.2	S59E	Neutral	0.32
BRCA1	P38398-1.2	S59F	Pathogenic	0.629
BRCA1	P38398-1.2	S59G	Neutral	0.272
BRCA1	P38398-1.2	S59H	Neutral	0.455
BRCA1	P38398-1.2	S59I	Pathogenic	0.571
BRCA1	P38398-1.2	S59K	Neutral	0.455
BRCA1	P38398-1.2	S59L	Pathogenic	0.571
BRCA1	P38398-1.2	S59M	Neutral	0.483
BRCA1	P38398-1.2	S59N	Neutral	0.197
BRCA1	P38398-1.2	S59P	Neutral	0.307
BRCA1	P38398-1.2	S59Q	Neutral	0.347
BRCA1	P38398-1.2	S59R	Pathogenic	0.615
BRCA1	P38398-1.2	S59T	Neutral	0.187
BRCA1	P38398-1.2	S59V	Neutral	0.468
BRCA1	P38398-1.2	S59W	Pathogenic	0.818
BRCA1	P38398-1.2	S59Y	Pathogenic	0.663
BRCA1	P38398-1.2	Q60A	Pathogenic	0.581
BRCA1	P38398-1.2	Q60C	Pathogenic	0.65
BRCA1	P38398-1.2	Q60D	Neutral	0.361
BRCA1	P38398-1.2	Q60E	Neutral	0.155
BRCA1	P38398-1.2	Q60F	Pathogenic	0.61
BRCA1	P38398-1.2	Q60G	Pathogenic	0.753
BRCA1	P38398-1.2	Q60H	Neutral	0.271
BRCA1	P38398-1.2	Q60I	Pathogenic	0.55
BRCA1	P38398-1.2	Q60K	Neutral	0.272
BRCA1	P38398-1.2	Q60L	Neutral	0.46
BRCA1	P38398-1.2	Q60M	Neutral	0.293
BRCA1	P38398-1.2	Q60N	Neutral	0.336
BRCA1	P38398-1.2	Q60P	Neutral	0.452
BRCA1	P38398-1.2	Q60R	Neutral	0.333
BRCA1	P38398-1.2	Q60S	Neutral	0.459
BRCA1	P38398-1.2	Q60T	Neutral	0.437
BRCA1	P38398-1.2	Q60V	Neutral	0.457
BRCA1	P38398-1.2	Q60W	Pathogenic	0.667
BRCA1	P38398-1.2	Q60Y	Neutral	0.467
BRCA1	P38398-1.2	C61A	Pathogenic	0.594
BRCA1	P38398-1.2	C61D	Pathogenic	0.758
BRCA1	P38398-1.2	C61E	Pathogenic	0.871
BRCA1	P38398-1.2	C61F	Pathogenic	0.855
BRCA1	P38398-1.2	C61G	Pathogenic	0.869
BRCA1	P38398-1.2	C61H	Pathogenic	0.853
BRCA1	P38398-1.2	C61I	Pathogenic	0.762
BRCA1	P38398-1.2	C61K	Pathogenic	0.892
BRCA1	P38398-1.2	C61L	Pathogenic	0.762
BRCA1	P38398-1.2	C61M	Pathogenic	0.764
BRCA1	P38398-1.2	C61N	Pathogenic	0.778
BRCA1	P38398-1.2	C61P	Pathogenic	0.759
BRCA1	P38398-1.2	C61Q	Pathogenic	0.84
BRCA1	P38398-1.2	C61R	Pathogenic	0.917
BRCA1	P38398-1.2	C61S	Pathogenic	0.647
BRCA1	P38398-1.2	C61T	Pathogenic	0.617
BRCA1	P38398-1.2	C61V	Pathogenic	0.68
BRCA1	P38398-1.2	C61W	Pathogenic	0.916
BRCA1	P38398-1.2	C61Y	Pathogenic	0.872
BRCA1	P38398-1.2	P62A	Pathogenic	0.679
BRCA1	P38398-1.2	P62C	Pathogenic	0.742
BRCA1	P38398-1.2	P62D	Pathogenic	0.56
BRCA1	P38398-1.2	P62E	Pathogenic	0.655
BRCA1	P38398-1.2	P62F	Pathogenic	0.91
BRCA1	P38398-1.2	P62G	Pathogenic	0.822
BRCA1	P38398-1.2	P62H	Pathogenic	0.772
BRCA1	P38398-1.2	P62I	Pathogenic	0.847
BRCA1	P38398-1.2	P62K	Pathogenic	0.771
BRCA1	P38398-1.2	P62L	Pathogenic	0.847
BRCA1	P38398-1.2	P62M	Pathogenic	0.795
BRCA1	P38398-1.2	P62N	Pathogenic	0.672
BRCA1	P38398-1.2	P62Q	Pathogenic	0.682
BRCA1	P38398-1.2	P62R	Pathogenic	0.866
BRCA1	P38398-1.2	P62S	Pathogenic	0.648
BRCA1	P38398-1.2	P62T	Pathogenic	0.575
BRCA1	P38398-1.2	P62V	Pathogenic	0.718
BRCA1	P38398-1.2	P62W	Pathogenic	0.949
BRCA1	P38398-1.2	P62Y	Pathogenic	0.891
BRCA1	P38398-1.2	L63A	Pathogenic	0.769
BRCA1	P38398-1.2	L63C	Pathogenic	0.689
BRCA1	P38398-1.2	L63D	Pathogenic	0.851
BRCA1	P38398-1.2	L63E	Pathogenic	0.727
BRCA1	P38398-1.2	L63F	Neutral	0.46
BRCA1	P38398-1.2	L63G	Pathogenic	0.938
BRCA1	P38398-1.2	L63H	Pathogenic	0.689
BRCA1	P38398-1.2	L63I	Neutral	0.244
BRCA1	P38398-1.2	L63K	Pathogenic	0.627
BRCA1	P38398-1.2	L63M	Neutral	0.243
BRCA1	P38398-1.2	L63N	Pathogenic	0.781
BRCA1	P38398-1.2	L63P	Pathogenic	0.806
BRCA1	P38398-1.2	L63Q	Pathogenic	0.625
BRCA1	P38398-1.2	L63R	Pathogenic	0.692
BRCA1	P38398-1.2	L63S	Pathogenic	0.806
BRCA1	P38398-1.2	L63T	Pathogenic	0.651
BRCA1	P38398-1.2	L63V	Neutral	0.413
BRCA1	P38398-1.2	L63W	Pathogenic	0.765
BRCA1	P38398-1.2	L63Y	Pathogenic	0.581
BRCA1	P38398-1.2	C64A	Pathogenic	0.691
BRCA1	P38398-1.2	C64D	Pathogenic	0.827
BRCA1	P38398-1.2	C64E	Pathogenic	0.911
BRCA1	P38398-1.2	C64F	Pathogenic	0.9
BRCA1	P38398-1.2	C64G	Pathogenic	0.91
BRCA1	P38398-1.2	C64H	Pathogenic	0.899
BRCA1	P38398-1.2	C64I	Pathogenic	0.83
BRCA1	P38398-1.2	C64K	Pathogenic	0.927
BRCA1	P38398-1.2	C64L	Pathogenic	0.83
BRCA1	P38398-1.2	C64M	Pathogenic	0.832
BRCA1	P38398-1.2	C64N	Pathogenic	0.843
BRCA1	P38398-1.2	C64P	Pathogenic	0.828
BRCA1	P38398-1.2	C64Q	Pathogenic	0.889
BRCA1	P38398-1.2	C64R	Pathogenic	0.944
BRCA1	P38398-1.2	C64S	Pathogenic	0.737
BRCA1	P38398-1.2	C64T	Pathogenic	0.711
BRCA1	P38398-1.2	C64V	Pathogenic	0.764
BRCA1	P38398-1.2	C64W	Pathogenic	0.943
BRCA1	P38398-1.2	C64Y	Pathogenic	0.912
BRCA1	P38398-1.2	K65A	Pathogenic	0.8
BRCA1	P38398-1.2	K65C	Pathogenic	0.843
BRCA1	P38398-1.2	K65D	Pathogenic	0.706
BRCA1	P38398-1.2	K65E	Neutral	0.437
BRCA1	P38398-1.2	K65F	Pathogenic	0.64
BRCA1	P38398-1.2	K65G	Pathogenic	0.898
BRCA1	P38398-1.2	K65H	Pathogenic	0.564
BRCA1	P38398-1.2	K65I	Pathogenic	0.695
BRCA1	P38398-1.2	K65L	Pathogenic	0.613
BRCA1	P38398-1.2	K65M	Pathogenic	0.526
BRCA1	P38398-1.2	K65N	Pathogenic	0.598
BRCA1	P38398-1.2	K65P	Pathogenic	0.705
BRCA1	P38398-1.2	K65Q	Neutral	0.408
BRCA1	P38398-1.2	K65R	Neutral	0.289
BRCA1	P38398-1.2	K65S	Pathogenic	0.71
BRCA1	P38398-1.2	K65T	Pathogenic	0.692
BRCA1	P38398-1.2	K65V	Pathogenic	0.709
BRCA1	P38398-1.2	K65W	Pathogenic	0.767
BRCA1	P38398-1.2	K65Y	Pathogenic	0.59
BRCA1	P38398-1.2	N66A	Neutral	0.468
BRCA1	P38398-1.2	N66C	Neutral	0.45
BRCA1	P38398-1.2	N66D	Neutral	0.149
BRCA1	P38398-1.2	N66E	Neutral	0.232
BRCA1	P38398-1.2	N66F	Pathogenic	0.605
BRCA1	P38398-1.2	N66G	Neutral	0.394
BRCA1	P38398-1.2	N66H	Neutral	0.202
BRCA1	P38398-1.2	N66I	Pathogenic	0.546
BRCA1	P38398-1.2	N66K	Neutral	0.348
BRCA1	P38398-1.2	N66L	Pathogenic	0.546
BRCA1	P38398-1.2	N66M	Neutral	0.458
BRCA1	P38398-1.2	N66P	Neutral	0.343
BRCA1	P38398-1.2	N66Q	Neutral	0.251
BRCA1	P38398-1.2	N66R	Neutral	0.416
BRCA1	P38398-1.2	N66S	Neutral	0.206
BRCA1	P38398-1.2	N66T	Neutral	0.192
BRCA1	P38398-1.2	N66V	Neutral	0.443
BRCA1	P38398-1.2	N66W	Pathogenic	0.803
BRCA1	P38398-1.2	N66Y	Pathogenic	0.553
BRCA1	P38398-1.2	D67A	Neutral	0.023
BRCA1	P38398-1.2	D67C	Neutral	0.022
BRCA1	P38398-1.2	D67E	Neutral	0.005
BRCA1	P38398-1.2	D67F	Neutral	0.05
BRCA1	P38398-1.2	D67G	Neutral	0.025
BRCA1	P38398-1.2	D67H	Neutral	0.018
BRCA1	P38398-1.2	D67I	Neutral	0.039
BRCA1	P38398-1.2	D67K	Neutral	0.026
BRCA1	P38398-1.2	D67L	Neutral	0.056
BRCA1	P38398-1.2	D67M	Neutral	0.04
BRCA1	P38398-1.2	D67N	Neutral	0.005
BRCA1	P38398-1.2	D67P	Neutral	0.01
BRCA1	P38398-1.2	D67Q	Neutral	0.011
BRCA1	P38398-1.2	D67R	Neutral	0.048
BRCA1	P38398-1.2	D67S	Neutral	0.01
BRCA1	P38398-1.2	D67T	Neutral	0.01
BRCA1	P38398-1.2	D67V	Neutral	0.026
BRCA1	P38398-1.2	D67W	Neutral	0.122
BRCA1	P38398-1.2	D67Y	Neutral	0.057
BRCA1	P38398-1.2	I68A	Pathogenic	0.635
BRCA1	P38398-1.2	I68C	Pathogenic	0.537
BRCA1	P38398-1.2	I68D	Pathogenic	0.675
BRCA1	P38398-1.2	I68E	Pathogenic	0.582
BRCA1	P38398-1.2	I68F	Neutral	0.31
BRCA1	P38398-1.2	I68G	Pathogenic	0.887
BRCA1	P38398-1.2	I68H	Pathogenic	0.537
BRCA1	P38398-1.2	I68K	Pathogenic	0.559
BRCA1	P38398-1.2	I68L	Neutral	0.145
BRCA1	P38398-1.2	I68M	Neutral	0.195
BRCA1	P38398-1.2	I68N	Pathogenic	0.651
BRCA1	P38398-1.2	I68P	Pathogenic	0.686
BRCA1	P38398-1.2	I68Q	Pathogenic	0.557
BRCA1	P38398-1.2	I68R	Pathogenic	0.628
BRCA1	P38398-1.2	I68S	Pathogenic	0.686
BRCA1	P38398-1.2	I68T	Neutral	0.494
BRCA1	P38398-1.2	I68V	Neutral	0.151
BRCA1	P38398-1.2	I68W	Pathogenic	0.712
BRCA1	P38398-1.2	I68Y	Neutral	0.421
BRCA1	P38398-1.2	T69A	Neutral	0.483
BRCA1	P38398-1.2	T69C	Neutral	0.465
BRCA1	P38398-1.2	T69D	Neutral	0.437
BRCA1	P38398-1.2	T69E	Pathogenic	0.515
BRCA1	P38398-1.2	T69F	Pathogenic	0.729
BRCA1	P38398-1.2	T69G	Pathogenic	0.746
BRCA1	P38398-1.2	T69H	Pathogenic	0.654
BRCA1	P38398-1.2	T69I	Pathogenic	0.594
BRCA1	P38398-1.2	T69K	Pathogenic	0.652
BRCA1	P38398-1.2	T69L	Pathogenic	0.594
BRCA1	P38398-1.2	T69M	Pathogenic	0.596
BRCA1	P38398-1.2	T69N	Neutral	0.356
BRCA1	P38398-1.2	T69P	Neutral	0.445
BRCA1	P38398-1.2	T69Q	Pathogenic	0.544
BRCA1	P38398-1.2	T69R	Pathogenic	0.715
BRCA1	P38398-1.2	T69S	Neutral	0.361
BRCA1	P38398-1.2	T69V	Neutral	0.402
BRCA1	P38398-1.2	T69W	Pathogenic	0.832
BRCA1	P38398-1.2	T69Y	Pathogenic	0.757
BRCA1	P38398-1.2	K70A	Neutral	0.419
BRCA1	P38398-1.2	K70C	Neutral	0.492
BRCA1	P38398-1.2	K70D	Neutral	0.302
BRCA1	P38398-1.2	K70E	Neutral	0.123
BRCA1	P38398-1.2	K70F	Neutral	0.243
BRCA1	P38398-1.2	K70G	Pathogenic	0.615
BRCA1	P38398-1.2	K70H	Neutral	0.189
BRCA1	P38398-1.2	K70I	Neutral	0.291
BRCA1	P38398-1.2	K70L	Neutral	0.222
BRCA1	P38398-1.2	K70M	Neutral	0.167
BRCA1	P38398-1.2	K70N	Neutral	0.212
BRCA1	P38398-1.2	K70P	Neutral	0.301
BRCA1	P38398-1.2	K70Q	Neutral	0.11
BRCA1	P38398-1.2	K70R	Neutral	0.068
BRCA1	P38398-1.2	K70S	Neutral	0.307
BRCA1	P38398-1.2	K70T	Neutral	0.289
BRCA1	P38398-1.2	K70V	Neutral	0.305
BRCA1	P38398-1.2	K70W	Neutral	0.372
BRCA1	P38398-1.2	K70Y	Neutral	0.206
BRCA1	P38398-1.2	R71A	Pathogenic	0.867
BRCA1	P38398-1.2	R71C	Pathogenic	0.897
BRCA1	P38398-1.2	R71D	Pathogenic	0.849
BRCA1	P38398-1.2	R71E	Pathogenic	0.644
BRCA1	P38398-1.2	R71F	Pathogenic	0.743
BRCA1	P38398-1.2	R71G	Pathogenic	0.935
BRCA1	P38398-1.2	R71H	Pathogenic	0.594
BRCA1	P38398-1.2	R71I	Pathogenic	0.787
BRCA1	P38398-1.2	R71K	Neutral	0.331
BRCA1	P38398-1.2	R71L	Pathogenic	0.72
BRCA1	P38398-1.2	R71M	Pathogenic	0.643
BRCA1	P38398-1.2	R71N	Pathogenic	0.707
BRCA1	P38398-1.2	R71P	Pathogenic	0.848
BRCA1	P38398-1.2	R71Q	Pathogenic	0.528
BRCA1	P38398-1.2	R71S	Pathogenic	0.851
BRCA1	P38398-1.2	R71T	Pathogenic	0.785
BRCA1	P38398-1.2	R71V	Pathogenic	0.851
BRCA1	P38398-1.2	R71W	Pathogenic	0.75
BRCA1	P38398-1.2	R71Y	Pathogenic	0.641
BRCA1	P38398-1.2	S72A	Neutral	0.347
BRCA1	P38398-1.2	S72C	Pathogenic	0.56
BRCA1	P38398-1.2	S72D	Neutral	0.498
BRCA1	P38398-1.2	S72E	Pathogenic	0.597
BRCA1	P38398-1.2	S72F	Pathogenic	0.842
BRCA1	P38398-1.2	S72G	Pathogenic	0.54
BRCA1	P38398-1.2	S72H	Pathogenic	0.724
BRCA1	P38398-1.2	S72I	Pathogenic	0.807
BRCA1	P38398-1.2	S72K	Pathogenic	0.724
BRCA1	P38398-1.2	S72L	Pathogenic	0.807
BRCA1	P38398-1.2	S72M	Pathogenic	0.746
BRCA1	P38398-1.2	S72N	Neutral	0.436
BRCA1	P38398-1.2	S72P	Pathogenic	0.583
BRCA1	P38398-1.2	S72Q	Pathogenic	0.626
BRCA1	P38398-1.2	S72R	Pathogenic	0.834
BRCA1	P38398-1.2	S72T	Neutral	0.421
BRCA1	P38398-1.2	S72V	Pathogenic	0.735
BRCA1	P38398-1.2	S72W	Pathogenic	0.934
BRCA1	P38398-1.2	S72Y	Pathogenic	0.861
BRCA1	P38398-1.2	L73A	Pathogenic	0.763
BRCA1	P38398-1.2	L73C	Pathogenic	0.682
BRCA1	P38398-1.2	L73D	Pathogenic	0.847
BRCA1	P38398-1.2	L73E	Pathogenic	0.72
BRCA1	P38398-1.2	L73F	Neutral	0.452
BRCA1	P38398-1.2	L73G	Pathogenic	0.936
BRCA1	P38398-1.2	L73H	Pathogenic	0.682
BRCA1	P38398-1.2	L73I	Neutral	0.238
BRCA1	P38398-1.2	L73K	Pathogenic	0.619
BRCA1	P38398-1.2	L73M	Neutral	0.237
BRCA1	P38398-1.2	L73N	Pathogenic	0.775
BRCA1	P38398-1.2	L73P	Pathogenic	0.801
BRCA1	P38398-1.2	L73Q	Pathogenic	0.618
BRCA1	P38398-1.2	L73R	Pathogenic	0.685
BRCA1	P38398-1.2	L73S	Pathogenic	0.801
BRCA1	P38398-1.2	L73T	Pathogenic	0.644
BRCA1	P38398-1.2	L73V	Neutral	0.405
BRCA1	P38398-1.2	L73W	Pathogenic	0.76
BRCA1	P38398-1.2	L73Y	Pathogenic	0.573
BRCA1	P38398-1.2	Q74A	Pathogenic	0.655
BRCA1	P38398-1.2	Q74C	Pathogenic	0.718
BRCA1	P38398-1.2	Q74D	Neutral	0.436
BRCA1	P38398-1.2	Q74E	Neutral	0.2
BRCA1	P38398-1.2	Q74F	Pathogenic	0.682
BRCA1	P38398-1.2	Q74G	Pathogenic	0.807
BRCA1	P38398-1.2	Q74H	Neutral	0.337
BRCA1	P38398-1.2	Q74I	Pathogenic	0.626
BRCA1	P38398-1.2	Q74K	Neutral	0.338
BRCA1	P38398-1.2	Q74L	Pathogenic	0.539
BRCA1	P38398-1.2	Q74M	Neutral	0.363
BRCA1	P38398-1.2	Q74N	Neutral	0.41
BRCA1	P38398-1.2	Q74P	Pathogenic	0.53
BRCA1	P38398-1.2	Q74R	Neutral	0.406
BRCA1	P38398-1.2	Q74S	Pathogenic	0.537
BRCA1	P38398-1.2	Q74T	Pathogenic	0.516
BRCA1	P38398-1.2	Q74V	Pathogenic	0.535
BRCA1	P38398-1.2	Q74W	Pathogenic	0.733
BRCA1	P38398-1.2	Q74Y	Pathogenic	0.546
BRCA1	P38398-1.2	E75A	Neutral	0.387
BRCA1	P38398-1.2	E75C	Pathogenic	0.549
BRCA1	P38398-1.2	E75D	Neutral	0.112
BRCA1	P38398-1.2	E75F	Neutral	0.471
BRCA1	P38398-1.2	E75G	Pathogenic	0.582
BRCA1	P38398-1.2	E75H	Neutral	0.174
BRCA1	P38398-1.2	E75I	Neutral	0.41
BRCA1	P38398-1.2	E75K	Neutral	0.177
BRCA1	P38398-1.2	E75L	Neutral	0.411
BRCA1	P38398-1.2	E75M	Neutral	0.328
BRCA1	P38398-1.2	E75N	Neutral	0.19
BRCA1	P38398-1.2	E75P	Neutral	0.273
BRCA1	P38398-1.2	E75Q	Neutral	0.086
BRCA1	P38398-1.2	E75R	Neutral	0.293
BRCA1	P38398-1.2	E75S	Neutral	0.278
BRCA1	P38398-1.2	E75T	Neutral	0.261
BRCA1	P38398-1.2	E75V	Neutral	0.277
BRCA1	P38398-1.2	E75W	Pathogenic	0.621
BRCA1	P38398-1.2	E75Y	Neutral	0.418
BRCA1	P38398-1.2	S76A	Neutral	0.104
BRCA1	P38398-1.2	S76C	Neutral	0.217
BRCA1	P38398-1.2	S76D	Neutral	0.177
BRCA1	P38398-1.2	S76E	Neutral	0.244
BRCA1	P38398-1.2	S76F	Pathogenic	0.538
BRCA1	P38398-1.2	S76G	Neutral	0.203
BRCA1	P38398-1.2	S76H	Neutral	0.364
BRCA1	P38398-1.2	S76I	Neutral	0.477
BRCA1	P38398-1.2	S76K	Neutral	0.363
BRCA1	P38398-1.2	S76L	Neutral	0.477
BRCA1	P38398-1.2	S76M	Neutral	0.39
BRCA1	P38398-1.2	S76N	Neutral	0.144
BRCA1	P38398-1.2	S76P	Neutral	0.233
BRCA1	P38398-1.2	S76Q	Neutral	0.267
BRCA1	P38398-1.2	S76R	Pathogenic	0.523
BRCA1	P38398-1.2	S76T	Neutral	0.136
BRCA1	P38398-1.2	S76V	Neutral	0.376
BRCA1	P38398-1.2	S76W	Pathogenic	0.755
BRCA1	P38398-1.2	S76Y	Pathogenic	0.574
BRCA1	P38398-1.2	T77A	Neutral	0.49
BRCA1	P38398-1.2	T77C	Neutral	0.472
BRCA1	P38398-1.2	T77D	Neutral	0.443
BRCA1	P38398-1.2	T77E	Pathogenic	0.521
BRCA1	P38398-1.2	T77F	Pathogenic	0.734
BRCA1	P38398-1.2	T77G	Pathogenic	0.751
BRCA1	P38398-1.2	T77H	Pathogenic	0.66
BRCA1	P38398-1.2	T77I	Pathogenic	0.6
BRCA1	P38398-1.2	T77K	Pathogenic	0.658
BRCA1	P38398-1.2	T77L	Pathogenic	0.6
BRCA1	P38398-1.2	T77M	Pathogenic	0.603
BRCA1	P38398-1.2	T77N	Neutral	0.362
BRCA1	P38398-1.2	T77P	Neutral	0.451
BRCA1	P38398-1.2	T77Q	Pathogenic	0.551
BRCA1	P38398-1.2	T77R	Pathogenic	0.72
BRCA1	P38398-1.2	T77S	Neutral	0.367
BRCA1	P38398-1.2	T77V	Neutral	0.409
BRCA1	P38398-1.2	T77W	Pathogenic	0.836
BRCA1	P38398-1.2	T77Y	Pathogenic	0.762
BRCA1	P38398-1.2	R78A	Pathogenic	0.883
BRCA1	P38398-1.2	R78C	Pathogenic	0.91
BRCA1	P38398-1.2	R78D	Pathogenic	0.866
BRCA1	P38398-1.2	R78E	Pathogenic	0.677
BRCA1	P38398-1.2	R78F	Pathogenic	0.77
BRCA1	P38398-1.2	R78G	Pathogenic	0.943
BRCA1	P38398-1.2	R78H	Pathogenic	0.628
BRCA1	P38398-1.2	R78I	Pathogenic	0.81
BRCA1	P38398-1.2	R78K	Neutral	0.363
BRCA1	P38398-1.2	R78L	Pathogenic	0.748
BRCA1	P38398-1.2	R78M	Pathogenic	0.675
BRCA1	P38398-1.2	R78N	Pathogenic	0.736
BRCA1	P38398-1.2	R78P	Pathogenic	0.866
BRCA1	P38398-1.2	R78Q	Pathogenic	0.563
BRCA1	P38398-1.2	R78S	Pathogenic	0.869
BRCA1	P38398-1.2	R78T	Pathogenic	0.808
BRCA1	P38398-1.2	R78V	Pathogenic	0.868
BRCA1	P38398-1.2	R78W	Pathogenic	0.776
BRCA1	P38398-1.2	R78Y	Pathogenic	0.674
BRCA1	P38398-1.2	F79A	Pathogenic	0.943
BRCA1	P38398-1.2	F79C	Pathogenic	0.917
BRCA1	P38398-1.2	F79D	Pathogenic	0.932
BRCA1	P38398-1.2	F79E	Pathogenic	0.902
BRCA1	P38398-1.2	F79G	Pathogenic	0.973
BRCA1	P38398-1.2	F79H	Pathogenic	0.788
BRCA1	P38398-1.2	F79I	Pathogenic	0.7
BRCA1	P38398-1.2	F79K	Pathogenic	0.838
BRCA1	P38398-1.2	F79L	Pathogenic	0.699
BRCA1	P38398-1.2	F79M	Pathogenic	0.697
BRCA1	P38398-1.2	F79N	Pathogenic	0.925
BRCA1	P38398-1.2	F79P	Pathogenic	0.954
BRCA1	P38398-1.2	F79Q	Pathogenic	0.893
BRCA1	P38398-1.2	F79R	Pathogenic	0.873
BRCA1	P38398-1.2	F79S	Pathogenic	0.935
BRCA1	P38398-1.2	F79T	Pathogenic	0.903
BRCA1	P38398-1.2	F79V	Pathogenic	0.835
BRCA1	P38398-1.2	F79W	Pathogenic	0.701
BRCA1	P38398-1.2	F79Y	Neutral	0.408
BRCA1	P38398-1.2	S80A	Neutral	0.119
BRCA1	P38398-1.2	S80C	Neutral	0.244
BRCA1	P38398-1.2	S80D	Neutral	0.201
BRCA1	P38398-1.2	S80E	Neutral	0.273
BRCA1	P38398-1.2	S80F	Pathogenic	0.576
BRCA1	P38398-1.2	S80G	Neutral	0.23
BRCA1	P38398-1.2	S80H	Neutral	0.4
BRCA1	P38398-1.2	S80I	Pathogenic	0.515
BRCA1	P38398-1.2	S80K	Neutral	0.4
BRCA1	P38398-1.2	S80L	Pathogenic	0.516
BRCA1	P38398-1.2	S80M	Neutral	0.427
BRCA1	P38398-1.2	S80N	Neutral	0.164
BRCA1	P38398-1.2	S80P	Neutral	0.262
BRCA1	P38398-1.2	S80Q	Neutral	0.298
BRCA1	P38398-1.2	S80R	Pathogenic	0.561
BRCA1	P38398-1.2	S80T	Neutral	0.156
BRCA1	P38398-1.2	S80V	Neutral	0.413
BRCA1	P38398-1.2	S80W	Pathogenic	0.783
BRCA1	P38398-1.2	S80Y	Pathogenic	0.612
BRCA1	P38398-1.2	Q81A	Pathogenic	0.812
BRCA1	P38398-1.2	Q81C	Pathogenic	0.853
BRCA1	P38398-1.2	Q81D	Pathogenic	0.637
BRCA1	P38398-1.2	Q81E	Neutral	0.363
BRCA1	P38398-1.2	Q81F	Pathogenic	0.83
BRCA1	P38398-1.2	Q81G	Pathogenic	0.905
BRCA1	P38398-1.2	Q81H	Pathogenic	0.536
BRCA1	P38398-1.2	Q81I	Pathogenic	0.792
BRCA1	P38398-1.2	Q81K	Pathogenic	0.538
BRCA1	P38398-1.2	Q81L	Pathogenic	0.726
BRCA1	P38398-1.2	Q81M	Pathogenic	0.564
BRCA1	P38398-1.2	Q81N	Pathogenic	0.612
BRCA1	P38398-1.2	Q81P	Pathogenic	0.72
BRCA1	P38398-1.2	Q81R	Pathogenic	0.608
BRCA1	P38398-1.2	Q81S	Pathogenic	0.725
BRCA1	P38398-1.2	Q81T	Pathogenic	0.708
BRCA1	P38398-1.2	Q81V	Pathogenic	0.724
BRCA1	P38398-1.2	Q81W	Pathogenic	0.862
BRCA1	P38398-1.2	Q81Y	Pathogenic	0.732
BRCA1	P38398-1.2	L82A	Pathogenic	0.808
BRCA1	P38398-1.2	L82C	Pathogenic	0.736
BRCA1	P38398-1.2	L82D	Pathogenic	0.878
BRCA1	P38398-1.2	L82E	Pathogenic	0.771
BRCA1	P38398-1.2	L82F	Pathogenic	0.519
BRCA1	P38398-1.2	L82G	Pathogenic	0.95
BRCA1	P38398-1.2	L82H	Pathogenic	0.737
BRCA1	P38398-1.2	L82I	Neutral	0.29
BRCA1	P38398-1.2	L82K	Pathogenic	0.68
BRCA1	P38398-1.2	L82M	Neutral	0.288
BRCA1	P38398-1.2	L82N	Pathogenic	0.818
BRCA1	P38398-1.2	L82P	Pathogenic	0.84
BRCA1	P38398-1.2	L82Q	Pathogenic	0.678
BRCA1	P38398-1.2	L82R	Pathogenic	0.739
BRCA1	P38398-1.2	L82S	Pathogenic	0.84
BRCA1	P38398-1.2	L82T	Pathogenic	0.702
BRCA1	P38398-1.2	L82V	Neutral	0.471
BRCA1	P38398-1.2	L82W	Pathogenic	0.805
BRCA1	P38398-1.2	L82Y	Pathogenic	0.637
BRCA1	P38398-1.2	V83A	Pathogenic	0.604
BRCA1	P38398-1.2	V83C	Pathogenic	0.593
BRCA1	P38398-1.2	V83D	Pathogenic	0.723
BRCA1	P38398-1.2	V83E	Pathogenic	0.593
BRCA1	P38398-1.2	V83F	Pathogenic	0.649
BRCA1	P38398-1.2	V83G	Pathogenic	0.873
BRCA1	P38398-1.2	V83H	Pathogenic	0.722
BRCA1	P38398-1.2	V83I	Neutral	0.252
BRCA1	P38398-1.2	V83K	Pathogenic	0.72
BRCA1	P38398-1.2	V83L	Neutral	0.412
BRCA1	P38398-1.2	V83M	Neutral	0.414
BRCA1	P38398-1.2	V83N	Pathogenic	0.701
BRCA1	P38398-1.2	V83P	Pathogenic	0.656
BRCA1	P38398-1.2	V83Q	Pathogenic	0.621
BRCA1	P38398-1.2	V83R	Pathogenic	0.832
BRCA1	P38398-1.2	V83S	Pathogenic	0.733
BRCA1	P38398-1.2	V83T	Neutral	0.461
BRCA1	P38398-1.2	V83W	Pathogenic	0.876
BRCA1	P38398-1.2	V83Y	Pathogenic	0.68
BRCA1	P38398-1.2	E84A	Pathogenic	0.724
BRCA1	P38398-1.2	E84C	Pathogenic	0.835
BRCA1	P38398-1.2	E84D	Neutral	0.344
BRCA1	P38398-1.2	E84F	Pathogenic	0.788
BRCA1	P38398-1.2	E84G	Pathogenic	0.853
BRCA1	P38398-1.2	E84H	Neutral	0.468
BRCA1	P38398-1.2	E84I	Pathogenic	0.744
BRCA1	P38398-1.2	E84K	Neutral	0.473
BRCA1	P38398-1.2	E84L	Pathogenic	0.744
BRCA1	P38398-1.2	E84M	Pathogenic	0.671
BRCA1	P38398-1.2	E84N	Neutral	0.494
BRCA1	P38398-1.2	E84P	Pathogenic	0.61
BRCA1	P38398-1.2	E84Q	Neutral	0.281
BRCA1	P38398-1.2	E84R	Pathogenic	0.633
BRCA1	P38398-1.2	E84S	Pathogenic	0.617
BRCA1	P38398-1.2	E84T	Pathogenic	0.596
BRCA1	P38398-1.2	E84V	Pathogenic	0.615
BRCA1	P38398-1.2	E84W	Pathogenic	0.872
BRCA1	P38398-1.2	E84Y	Pathogenic	0.749
BRCA1	P38398-1.2	E85A	Pathogenic	0.597
BRCA1	P38398-1.2	E85C	Pathogenic	0.741
BRCA1	P38398-1.2	E85D	Neutral	0.229
BRCA1	P38398-1.2	E85F	Pathogenic	0.677
BRCA1	P38398-1.2	E85G	Pathogenic	0.766
BRCA1	P38398-1.2	E85H	Neutral	0.332
BRCA1	P38398-1.2	E85I	Pathogenic	0.621
BRCA1	P38398-1.2	E85K	Neutral	0.337
BRCA1	P38398-1.2	E85L	Pathogenic	0.621
BRCA1	P38398-1.2	E85M	Pathogenic	0.535
BRCA1	P38398-1.2	E85N	Neutral	0.355
BRCA1	P38398-1.2	E85P	Neutral	0.469
BRCA1	P38398-1.2	E85Q	Neutral	0.181
BRCA1	P38398-1.2	E85R	Neutral	0.494
BRCA1	P38398-1.2	E85S	Neutral	0.476
BRCA1	P38398-1.2	E85T	Neutral	0.455
BRCA1	P38398-1.2	E85V	Neutral	0.474
BRCA1	P38398-1.2	E85W	Pathogenic	0.794
BRCA1	P38398-1.2	E85Y	Pathogenic	0.628
BRCA1	P38398-1.2	L86A	Pathogenic	0.849
BRCA1	P38398-1.2	L86C	Pathogenic	0.789
BRCA1	P38398-1.2	L86D	Pathogenic	0.906
BRCA1	P38398-1.2	L86E	Pathogenic	0.818
BRCA1	P38398-1.2	L86F	Pathogenic	0.591
BRCA1	P38398-1.2	L86G	Pathogenic	0.962
BRCA1	P38398-1.2	L86H	Pathogenic	0.789
BRCA1	P38398-1.2	L86I	Neutral	0.353
BRCA1	P38398-1.2	L86K	Pathogenic	0.74
BRCA1	P38398-1.2	L86M	Neutral	0.352
BRCA1	P38398-1.2	L86N	Pathogenic	0.858
BRCA1	P38398-1.2	L86P	Pathogenic	0.876
BRCA1	P38398-1.2	L86Q	Pathogenic	0.739
BRCA1	P38398-1.2	L86R	Pathogenic	0.792
BRCA1	P38398-1.2	L86S	Pathogenic	0.876
BRCA1	P38398-1.2	L86T	Pathogenic	0.76
BRCA1	P38398-1.2	L86V	Pathogenic	0.544
BRCA1	P38398-1.2	L86W	Pathogenic	0.847
BRCA1	P38398-1.2	L86Y	Pathogenic	0.701
BRCA1	P38398-1.2	L87A	Pathogenic	0.659
BRCA1	P38398-1.2	L87C	Pathogenic	0.562
BRCA1	P38398-1.2	L87D	Pathogenic	0.768
BRCA1	P38398-1.2	L87E	Pathogenic	0.607
BRCA1	P38398-1.2	L87F	Neutral	0.331
BRCA1	P38398-1.2	L87G	Pathogenic	0.897
BRCA1	P38398-1.2	L87H	Pathogenic	0.562
BRCA1	P38398-1.2	L87I	Neutral	0.158
BRCA1	P38398-1.2	L87K	Neutral	0.494
BRCA1	P38398-1.2	L87M	Neutral	0.157
BRCA1	P38398-1.2	L87N	Pathogenic	0.673
BRCA1	P38398-1.2	L87P	Pathogenic	0.707
BRCA1	P38398-1.2	L87Q	Neutral	0.492
BRCA1	P38398-1.2	L87R	Pathogenic	0.565
BRCA1	P38398-1.2	L87S	Pathogenic	0.707
BRCA1	P38398-1.2	L87T	Pathogenic	0.52
BRCA1	P38398-1.2	L87V	Neutral	0.29
BRCA1	P38398-1.2	L87W	Pathogenic	0.654
BRCA1	P38398-1.2	L87Y	Neutral	0.446
BRCA1	P38398-1.2	K88A	Pathogenic	0.617
BRCA1	P38398-1.2	K88C	Pathogenic	0.683
BRCA1	P38398-1.2	K88D	Neutral	0.491
BRCA1	P38398-1.2	K88E	Neutral	0.237
BRCA1	P38398-1.2	K88F	Neutral	0.417
BRCA1	P38398-1.2	K88G	Pathogenic	0.78
BRCA1	P38398-1.2	K88H	Neutral	0.342
BRCA1	P38398-1.2	K88I	Neutral	0.477
BRCA1	P38398-1.2	K88L	Neutral	0.389
BRCA1	P38398-1.2	K88M	Neutral	0.308
BRCA1	P38398-1.2	K88N	Neutral	0.374
BRCA1	P38398-1.2	K88P	Neutral	0.489
BRCA1	P38398-1.2	K88Q	Neutral	0.217
BRCA1	P38398-1.2	K88R	Neutral	0.14
BRCA1	P38398-1.2	K88S	Neutral	0.496
BRCA1	P38398-1.2	K88T	Neutral	0.475
BRCA1	P38398-1.2	K88V	Neutral	0.495
BRCA1	P38398-1.2	K88W	Pathogenic	0.569
BRCA1	P38398-1.2	K88Y	Neutral	0.366
BRCA1	P38398-1.2	I89A	Neutral	0.236
BRCA1	P38398-1.2	I89C	Neutral	0.17
BRCA1	P38398-1.2	I89D	Neutral	0.269
BRCA1	P38398-1.2	I89E	Neutral	0.198
BRCA1	P38398-1.2	I89F	Neutral	0.074
BRCA1	P38398-1.2	I89G	Pathogenic	0.583
BRCA1	P38398-1.2	I89H	Neutral	0.171
BRCA1	P38398-1.2	I89K	Neutral	0.184
BRCA1	P38398-1.2	I89L	Neutral	0.029
BRCA1	P38398-1.2	I89M	Neutral	0.041
BRCA1	P38398-1.2	I89N	Neutral	0.248
BRCA1	P38398-1.2	I89P	Neutral	0.279
BRCA1	P38398-1.2	I89Q	Neutral	0.183
BRCA1	P38398-1.2	I89R	Neutral	0.231
BRCA1	P38398-1.2	I89S	Neutral	0.279
BRCA1	P38398-1.2	I89T	Neutral	0.148
BRCA1	P38398-1.2	I89V	Neutral	0.031
BRCA1	P38398-1.2	I89W	Neutral	0.305
BRCA1	P38398-1.2	I89Y	Neutral	0.114
BRCA1	P38398-1.2	I90A	Pathogenic	0.661
BRCA1	P38398-1.2	I90C	Pathogenic	0.564
BRCA1	P38398-1.2	I90D	Pathogenic	0.699
BRCA1	P38398-1.2	I90E	Pathogenic	0.609
BRCA1	P38398-1.2	I90F	Neutral	0.334
BRCA1	P38398-1.2	I90G	Pathogenic	0.898
BRCA1	P38398-1.2	I90H	Pathogenic	0.565
BRCA1	P38398-1.2	I90K	Pathogenic	0.586
BRCA1	P38398-1.2	I90L	Neutral	0.159
BRCA1	P38398-1.2	I90M	Neutral	0.213
BRCA1	P38398-1.2	I90N	Pathogenic	0.676
BRCA1	P38398-1.2	I90P	Pathogenic	0.709
BRCA1	P38398-1.2	I90Q	Pathogenic	0.585
BRCA1	P38398-1.2	I90R	Pathogenic	0.654
BRCA1	P38398-1.2	I90S	Pathogenic	0.709
BRCA1	P38398-1.2	I90T	Pathogenic	0.522
BRCA1	P38398-1.2	I90V	Neutral	0.166
BRCA1	P38398-1.2	I90W	Pathogenic	0.734
BRCA1	P38398-1.2	I90Y	Neutral	0.448
BRCA1	P38398-1.2	C91A	Neutral	0.014
BRCA1	P38398-1.2	C91D	Neutral	0.03
BRCA1	P38398-1.2	C91E	Neutral	0.063
BRCA1	P38398-1.2	C91F	Neutral	0.055
BRCA1	P38398-1.2	C91G	Neutral	0.062
BRCA1	P38398-1.2	C91H	Neutral	0.054
BRCA1	P38398-1.2	C91I	Neutral	0.031
BRCA1	P38398-1.2	C91K	Neutral	0.076
BRCA1	P38398-1.2	C91L	Neutral	0.031
BRCA1	P38398-1.2	C91M	Neutral	0.031
BRCA1	P38398-1.2	C91N	Neutral	0.034
BRCA1	P38398-1.2	C91P	Neutral	0.03
BRCA1	P38398-1.2	C91Q	Neutral	0.05
BRCA1	P38398-1.2	C91R	Neutral	0.099
BRCA1	P38398-1.2	C91S	Neutral	0.018
BRCA1	P38398-1.2	C91T	Neutral	0.016
BRCA1	P38398-1.2	C91V	Neutral	0.021
BRCA1	P38398-1.2	C91W	Neutral	0.097
BRCA1	P38398-1.2	C91Y	Neutral	0.063
BRCA1	P38398-1.2	A92C	Pathogenic	0.63
BRCA1	P38398-1.2	A92D	Pathogenic	0.797
BRCA1	P38398-1.2	A92E	Pathogenic	0.803
BRCA1	P38398-1.2	A92F	Pathogenic	0.912
BRCA1	P38398-1.2	A92G	Pathogenic	0.632
BRCA1	P38398-1.2	A92H	Pathogenic	0.879
BRCA1	P38398-1.2	A92I	Pathogenic	0.849
BRCA1	P38398-1.2	A92K	Pathogenic	0.878
BRCA1	P38398-1.2	A92L	Pathogenic	0.849
BRCA1	P38398-1.2	A92M	Pathogenic	0.85
BRCA1	P38398-1.2	A92N	Pathogenic	0.814
BRCA1	P38398-1.2	A92P	Pathogenic	0.729
BRCA1	P38398-1.2	A92Q	Pathogenic	0.821
BRCA1	P38398-1.2	A92R	Pathogenic	0.906
BRCA1	P38398-1.2	A92S	Neutral	0.472
BRCA1	P38398-1.2	A92T	Pathogenic	0.668
BRCA1	P38398-1.2	A92V	Pathogenic	0.721
BRCA1	P38398-1.2	A92W	Pathogenic	0.965
BRCA1	P38398-1.2	A92Y	Pathogenic	0.923
BRCA1	P38398-1.2	F93A	Pathogenic	0.94
BRCA1	P38398-1.2	F93C	Pathogenic	0.912
BRCA1	P38398-1.2	F93D	Pathogenic	0.928
BRCA1	P38398-1.2	F93E	Pathogenic	0.896
BRCA1	P38398-1.2	F93G	Pathogenic	0.971
BRCA1	P38398-1.2	F93H	Pathogenic	0.776
BRCA1	P38398-1.2	F93I	Pathogenic	0.685
BRCA1	P38398-1.2	F93K	Pathogenic	0.828
BRCA1	P38398-1.2	F93L	Pathogenic	0.685
BRCA1	P38398-1.2	F93M	Pathogenic	0.683
BRCA1	P38398-1.2	F93N	Pathogenic	0.92
BRCA1	P38398-1.2	F93P	Pathogenic	0.951
BRCA1	P38398-1.2	F93Q	Pathogenic	0.886
BRCA1	P38398-1.2	F93R	Pathogenic	0.866
BRCA1	P38398-1.2	F93S	Pathogenic	0.931
BRCA1	P38398-1.2	F93T	Pathogenic	0.897
BRCA1	P38398-1.2	F93V	Pathogenic	0.826
BRCA1	P38398-1.2	F93W	Pathogenic	0.687
BRCA1	P38398-1.2	F93Y	Neutral	0.392
BRCA1	P38398-1.2	Q94A	Neutral	0.3
BRCA1	P38398-1.2	Q94C	Neutral	0.364
BRCA1	P38398-1.2	Q94D	Neutral	0.148
BRCA1	P38398-1.2	Q94E	Neutral	0.054
BRCA1	P38398-1.2	Q94F	Neutral	0.326
BRCA1	P38398-1.2	Q94G	Neutral	0.486
BRCA1	P38398-1.2	Q94H	Neutral	0.103
BRCA1	P38398-1.2	Q94I	Neutral	0.274
BRCA1	P38398-1.2	Q94K	Neutral	0.103
BRCA1	P38398-1.2	Q94L	Neutral	0.208
BRCA1	P38398-1.2	Q94M	Neutral	0.114
BRCA1	P38398-1.2	Q94N	Neutral	0.135
BRCA1	P38398-1.2	Q94P	Neutral	0.203
BRCA1	P38398-1.2	Q94R	Neutral	0.133
BRCA1	P38398-1.2	Q94S	Neutral	0.208
BRCA1	P38398-1.2	Q94T	Neutral	0.194
BRCA1	P38398-1.2	Q94V	Neutral	0.206
BRCA1	P38398-1.2	Q94W	Neutral	0.383
BRCA1	P38398-1.2	Q94Y	Neutral	0.213
BRCA1	P38398-1.2	L95A	Pathogenic	0.803
BRCA1	P38398-1.2	L95C	Pathogenic	0.73
BRCA1	P38398-1.2	L95D	Pathogenic	0.875
BRCA1	P38398-1.2	L95E	Pathogenic	0.765
BRCA1	P38398-1.2	L95F	Pathogenic	0.511
BRCA1	P38398-1.2	L95G	Pathogenic	0.948
BRCA1	P38398-1.2	L95H	Pathogenic	0.73
BRCA1	P38398-1.2	L95I	Neutral	0.283
BRCA1	P38398-1.2	L95K	Pathogenic	0.673
BRCA1	P38398-1.2	L95M	Neutral	0.282
BRCA1	P38398-1.2	L95N	Pathogenic	0.813
BRCA1	P38398-1.2	L95P	Pathogenic	0.836
BRCA1	P38398-1.2	L95Q	Pathogenic	0.671
BRCA1	P38398-1.2	L95R	Pathogenic	0.733
BRCA1	P38398-1.2	L95S	Pathogenic	0.836
BRCA1	P38398-1.2	L95T	Pathogenic	0.696
BRCA1	P38398-1.2	L95V	Neutral	0.463
BRCA1	P38398-1.2	L95W	Pathogenic	0.8
BRCA1	P38398-1.2	L95Y	Pathogenic	0.629
BRCA1	P38398-1.2	D96A	Pathogenic	0.798
BRCA1	P38398-1.2	D96C	Pathogenic	0.787
BRCA1	P38398-1.2	D96E	Neutral	0.451
BRCA1	P38398-1.2	D96F	Pathogenic	0.896
BRCA1	P38398-1.2	D96G	Pathogenic	0.808
BRCA1	P38398-1.2	D96H	Pathogenic	0.747
BRCA1	P38398-1.2	D96I	Pathogenic	0.871
BRCA1	P38398-1.2	D96K	Pathogenic	0.813
BRCA1	P38398-1.2	D96L	Pathogenic	0.907
BRCA1	P38398-1.2	D96M	Pathogenic	0.872
BRCA1	P38398-1.2	D96N	Neutral	0.47
BRCA1	P38398-1.2	D96P	Pathogenic	0.621
BRCA1	P38398-1.2	D96Q	Pathogenic	0.654
BRCA1	P38398-1.2	D96R	Pathogenic	0.893
BRCA1	P38398-1.2	D96S	Pathogenic	0.627
BRCA1	P38398-1.2	D96T	Pathogenic	0.628
BRCA1	P38398-1.2	D96V	Pathogenic	0.818
BRCA1	P38398-1.2	D96W	Pathogenic	0.958
BRCA1	P38398-1.2	D96Y	Pathogenic	0.909
BRCA1	P38398-1.2	T97A	Neutral	0.134
BRCA1	P38398-1.2	T97C	Neutral	0.126
BRCA1	P38398-1.2	T97D	Neutral	0.114
BRCA1	P38398-1.2	T97E	Neutral	0.149
BRCA1	P38398-1.2	T97F	Neutral	0.308
BRCA1	P38398-1.2	T97G	Neutral	0.328
BRCA1	P38398-1.2	T97H	Neutral	0.239
BRCA1	P38398-1.2	T97I	Neutral	0.195
BRCA1	P38398-1.2	T97K	Neutral	0.237
BRCA1	P38398-1.2	T97L	Neutral	0.195
BRCA1	P38398-1.2	T97M	Neutral	0.197
BRCA1	P38398-1.2	T97N	Neutral	0.084
BRCA1	P38398-1.2	T97P	Neutral	0.117
BRCA1	P38398-1.2	T97Q	Neutral	0.165
BRCA1	P38398-1.2	T97R	Neutral	0.293
BRCA1	P38398-1.2	T97S	Neutral	0.086
BRCA1	P38398-1.2	T97V	Neutral	0.1
BRCA1	P38398-1.2	T97W	Neutral	0.451
BRCA1	P38398-1.2	T97Y	Neutral	0.341
BRCA1	P38398-1.2	G98A	Neutral	0.398
BRCA1	P38398-1.2	G98C	Pathogenic	0.748
BRCA1	P38398-1.2	G98D	Pathogenic	0.616
BRCA1	P38398-1.2	G98E	Pathogenic	0.775
BRCA1	P38398-1.2	G98F	Pathogenic	0.896
BRCA1	P38398-1.2	G98H	Pathogenic	0.81
BRCA1	P38398-1.2	G98I	Pathogenic	0.907
BRCA1	P38398-1.2	G98K	Pathogenic	0.859
BRCA1	P38398-1.2	G98L	Pathogenic	0.907
BRCA1	P38398-1.2	G98M	Pathogenic	0.873
BRCA1	P38398-1.2	G98N	Pathogenic	0.556
BRCA1	P38398-1.2	G98P	Pathogenic	0.693
BRCA1	P38398-1.2	G98Q	Pathogenic	0.796
BRCA1	P38398-1.2	G98R	Pathogenic	0.891
BRCA1	P38398-1.2	G98S	Neutral	0.431
BRCA1	P38398-1.2	G98T	Pathogenic	0.709
BRCA1	P38398-1.2	G98V	Pathogenic	0.818
BRCA1	P38398-1.2	G98W	Pathogenic	0.917
BRCA1	P38398-1.2	G98Y	Pathogenic	0.91
BRCA1	P38398-1.2	L99A	Neutral	0.151
BRCA1	P38398-1.2	L99C	Neutral	0.106
BRCA1	P38398-1.2	L99D	Neutral	0.234
BRCA1	P38398-1.2	L99E	Neutral	0.125
BRCA1	P38398-1.2	L99F	Neutral	0.044
BRCA1	P38398-1.2	L99G	Neutral	0.446
BRCA1	P38398-1.2	L99H	Neutral	0.106
BRCA1	P38398-1.2	L99I	Neutral	0.017
BRCA1	P38398-1.2	L99K	Neutral	0.083
BRCA1	P38398-1.2	L99M	Neutral	0.017
BRCA1	P38398-1.2	L99N	Neutral	0.16
BRCA1	P38398-1.2	L99P	Neutral	0.183
BRCA1	P38398-1.2	L99Q	Neutral	0.082
BRCA1	P38398-1.2	L99R	Neutral	0.107
BRCA1	P38398-1.2	L99S	Neutral	0.182
BRCA1	P38398-1.2	L99T	Neutral	0.091
BRCA1	P38398-1.2	L99V	Neutral	0.036
BRCA1	P38398-1.2	L99W	Neutral	0.149
BRCA1	P38398-1.2	L99Y	Neutral	0.069
BRCA1	P38398-1.2	E100A	Neutral	0.085
BRCA1	P38398-1.2	E100C	Neutral	0.153
BRCA1	P38398-1.2	E100D	Neutral	0.018
BRCA1	P38398-1.2	E100F	Neutral	0.116
BRCA1	P38398-1.2	E100G	Neutral	0.171
BRCA1	P38398-1.2	E100H	Neutral	0.03
BRCA1	P38398-1.2	E100I	Neutral	0.094
BRCA1	P38398-1.2	E100K	Neutral	0.031
BRCA1	P38398-1.2	E100L	Neutral	0.094
BRCA1	P38398-1.2	E100M	Neutral	0.068
BRCA1	P38398-1.2	E100N	Neutral	0.034
BRCA1	P38398-1.2	E100P	Neutral	0.053
BRCA1	P38398-1.2	E100Q	Neutral	0.014
BRCA1	P38398-1.2	E100R	Neutral	0.058
BRCA1	P38398-1.2	E100S	Neutral	0.054
BRCA1	P38398-1.2	E100T	Neutral	0.05
BRCA1	P38398-1.2	E100V	Neutral	0.054
BRCA1	P38398-1.2	E100W	Neutral	0.196
BRCA1	P38398-1.2	E100Y	Neutral	0.096
BRCA1	P38398-1.2	Y101A	Neutral	0.102
BRCA1	P38398-1.2	Y101C	Neutral	0.07
BRCA1	P38398-1.2	Y101D	Neutral	0.086
BRCA1	P38398-1.2	Y101E	Neutral	0.042
BRCA1	P38398-1.2	Y101F	Neutral	0.004
BRCA1	P38398-1.2	Y101G	Neutral	0.199
BRCA1	P38398-1.2	Y101H	Neutral	0.008
BRCA1	P38398-1.2	Y101I	Neutral	0.022
BRCA1	P38398-1.2	Y101K	Neutral	0.024
BRCA1	P38398-1.2	Y101L	Neutral	0.022
BRCA1	P38398-1.2	Y101M	Neutral	0.022
BRCA1	P38398-1.2	Y101N	Neutral	0.056
BRCA1	P38398-1.2	Y101P	Neutral	0.09
BRCA1	P38398-1.2	Y101Q	Neutral	0.027
BRCA1	P38398-1.2	Y101R	Neutral	0.025
BRCA1	P38398-1.2	Y101S	Neutral	0.09
BRCA1	P38398-1.2	Y101T	Neutral	0.06
BRCA1	P38398-1.2	Y101V	Neutral	0.033
BRCA1	P38398-1.2	Y101W	Neutral	0.008
BRCA1	P38398-1.2	A102C	Neutral	0.074
BRCA1	P38398-1.2	A102D	Neutral	0.156
BRCA1	P38398-1.2	A102E	Neutral	0.161
BRCA1	P38398-1.2	A102F	Neutral	0.327
BRCA1	P38398-1.2	A102G	Neutral	0.075
BRCA1	P38398-1.2	A102H	Neutral	0.255
BRCA1	P38398-1.2	A102I	Neutral	0.209
BRCA1	P38398-1.2	A102K	Neutral	0.253
BRCA1	P38398-1.2	A102L	Neutral	0.21
BRCA1	P38398-1.2	A102M	Neutral	0.211
BRCA1	P38398-1.2	A102N	Neutral	0.171
BRCA1	P38398-1.2	A102P	Neutral	0.113
BRCA1	P38398-1.2	A102Q	Neutral	0.178
BRCA1	P38398-1.2	A102R	Neutral	0.312
BRCA1	P38398-1.2	A102S	Neutral	0.04
BRCA1	P38398-1.2	A102T	Neutral	0.087
BRCA1	P38398-1.2	A102V	Neutral	0.109
BRCA1	P38398-1.2	A102W	Pathogenic	0.564
BRCA1	P38398-1.2	A102Y	Neutral	0.361
BRCA1	P38398-1.2	N103A	Neutral	0.386
BRCA1	P38398-1.2	N103C	Neutral	0.369
BRCA1	P38398-1.2	N103D	Neutral	0.111
BRCA1	P38398-1.2	N103E	Neutral	0.178
BRCA1	P38398-1.2	N103F	Pathogenic	0.523
BRCA1	P38398-1.2	N103G	Neutral	0.318
BRCA1	P38398-1.2	N103H	Neutral	0.153
BRCA1	P38398-1.2	N103I	Neutral	0.462
BRCA1	P38398-1.2	N103K	Neutral	0.277
BRCA1	P38398-1.2	N103L	Neutral	0.463
BRCA1	P38398-1.2	N103M	Neutral	0.376
BRCA1	P38398-1.2	N103P	Neutral	0.272
BRCA1	P38398-1.2	N103Q	Neutral	0.194
BRCA1	P38398-1.2	N103R	Neutral	0.338
BRCA1	P38398-1.2	N103S	Neutral	0.157
BRCA1	P38398-1.2	N103T	Neutral	0.146
BRCA1	P38398-1.2	N103V	Neutral	0.363
BRCA1	P38398-1.2	N103W	Pathogenic	0.745
BRCA1	P38398-1.2	N103Y	Neutral	0.47
BRCA1	P38398-1.2	S104A	Neutral	0.052
BRCA1	P38398-1.2	S104C	Neutral	0.116
BRCA1	P38398-1.2	S104D	Neutral	0.093
BRCA1	P38398-1.2	S104E	Neutral	0.133
BRCA1	P38398-1.2	S104F	Neutral	0.355
BRCA1	P38398-1.2	S104G	Neutral	0.108
BRCA1	P38398-1.2	S104H	Neutral	0.213
BRCA1	P38398-1.2	S104I	Neutral	0.301
BRCA1	P38398-1.2	S104K	Neutral	0.213
BRCA1	P38398-1.2	S104L	Neutral	0.302
BRCA1	P38398-1.2	S104M	Neutral	0.232
BRCA1	P38398-1.2	S104N	Neutral	0.074
BRCA1	P38398-1.2	S104P	Neutral	0.126
BRCA1	P38398-1.2	S104Q	Neutral	0.147
BRCA1	P38398-1.2	S104R	Neutral	0.342
BRCA1	P38398-1.2	S104T	Neutral	0.07
BRCA1	P38398-1.2	S104V	Neutral	0.222
BRCA1	P38398-1.2	S104W	Pathogenic	0.594
BRCA1	P38398-1.2	S104Y	Neutral	0.39
BRCA1	P38398-1.2	Y105A	Pathogenic	0.646
BRCA1	P38398-1.2	Y105C	Pathogenic	0.548
BRCA1	P38398-1.2	Y105D	Pathogenic	0.601
BRCA1	P38398-1.2	Y105E	Neutral	0.413
BRCA1	P38398-1.2	Y105F	Neutral	0.061
BRCA1	P38398-1.2	Y105G	Pathogenic	0.799
BRCA1	P38398-1.2	Y105H	Neutral	0.12
BRCA1	P38398-1.2	Y105I	Neutral	0.263
BRCA1	P38398-1.2	Y105K	Neutral	0.282
BRCA1	P38398-1.2	Y105L	Neutral	0.263
BRCA1	P38398-1.2	Y105M	Neutral	0.265
BRCA1	P38398-1.2	Y105N	Neutral	0.485
BRCA1	P38398-1.2	Y105P	Pathogenic	0.613
BRCA1	P38398-1.2	Y105Q	Neutral	0.306
BRCA1	P38398-1.2	Y105R	Neutral	0.286
BRCA1	P38398-1.2	Y105S	Pathogenic	0.613
BRCA1	P38398-1.2	Y105T	Pathogenic	0.506
BRCA1	P38398-1.2	Y105V	Neutral	0.354
BRCA1	P38398-1.2	Y105W	Neutral	0.117
BRCA1	P38398-1.2	N106A	Neutral	0.071
BRCA1	P38398-1.2	N106C	Neutral	0.066
BRCA1	P38398-1.2	N106D	Neutral	0.015
BRCA1	P38398-1.2	N106E	Neutral	0.026
BRCA1	P38398-1.2	N106F	Neutral	0.118
BRCA1	P38398-1.2	N106G	Neutral	0.054
BRCA1	P38398-1.2	N106H	Neutral	0.022
BRCA1	P38398-1.2	N106I	Neutral	0.095
BRCA1	P38398-1.2	N106K	Neutral	0.044
BRCA1	P38398-1.2	N106L	Neutral	0.095
BRCA1	P38398-1.2	N106M	Neutral	0.068
BRCA1	P38398-1.2	N106P	Neutral	0.044
BRCA1	P38398-1.2	N106Q	Neutral	0.028
BRCA1	P38398-1.2	N106R	Neutral	0.058
BRCA1	P38398-1.2	N106S	Neutral	0.022
BRCA1	P38398-1.2	N106T	Neutral	0.02
BRCA1	P38398-1.2	N106V	Neutral	0.065
BRCA1	P38398-1.2	N106W	Neutral	0.262
BRCA1	P38398-1.2	N106Y	Neutral	0.097
BRCA1	P38398-1.2	F107A	Pathogenic	0.813
BRCA1	P38398-1.2	F107C	Pathogenic	0.743
BRCA1	P38398-1.2	F107D	Pathogenic	0.782
BRCA1	P38398-1.2	F107E	Pathogenic	0.707
BRCA1	P38398-1.2	F107G	Pathogenic	0.904
BRCA1	P38398-1.2	F107H	Neutral	0.492
BRCA1	P38398-1.2	F107I	Neutral	0.378
BRCA1	P38398-1.2	F107K	Pathogenic	0.574
BRCA1	P38398-1.2	F107L	Neutral	0.378
BRCA1	P38398-1.2	F107M	Neutral	0.376
BRCA1	P38398-1.2	F107N	Pathogenic	0.763
BRCA1	P38398-1.2	F107P	Pathogenic	0.845
BRCA1	P38398-1.2	F107Q	Pathogenic	0.685
BRCA1	P38398-1.2	F107R	Pathogenic	0.642
BRCA1	P38398-1.2	F107S	Pathogenic	0.791
BRCA1	P38398-1.2	F107T	Pathogenic	0.709
BRCA1	P38398-1.2	F107V	Pathogenic	0.569
BRCA1	P38398-1.2	F107W	Neutral	0.379
BRCA1	P38398-1.2	F107Y	Neutral	0.152
BRCA1	P38398-1.2	A108C	Neutral	0.053
BRCA1	P38398-1.2	A108D	Neutral	0.114
BRCA1	P38398-1.2	A108E	Neutral	0.117
BRCA1	P38398-1.2	A108F	Neutral	0.252
BRCA1	P38398-1.2	A108G	Neutral	0.053
BRCA1	P38398-1.2	A108H	Neutral	0.192
BRCA1	P38398-1.2	A108I	Neutral	0.155
BRCA1	P38398-1.2	A108K	Neutral	0.191
BRCA1	P38398-1.2	A108L	Neutral	0.156
BRCA1	P38398-1.2	A108M	Neutral	0.157
BRCA1	P38398-1.2	A108N	Neutral	0.126
BRCA1	P38398-1.2	A108P	Neutral	0.081
BRCA1	P38398-1.2	A108Q	Neutral	0.13
BRCA1	P38398-1.2	A108R	Neutral	0.239
BRCA1	P38398-1.2	A108S	Neutral	0.028
BRCA1	P38398-1.2	A108T	Neutral	0.062
BRCA1	P38398-1.2	A108V	Neutral	0.078
BRCA1	P38398-1.2	A108W	Neutral	0.473
BRCA1	P38398-1.2	A108Y	Neutral	0.282
BRCA1	P38398-1.2	K109A	Pathogenic	0.564
BRCA1	P38398-1.2	K109C	Pathogenic	0.634
BRCA1	P38398-1.2	K109D	Neutral	0.436
BRCA1	P38398-1.2	K109E	Neutral	0.2
BRCA1	P38398-1.2	K109F	Neutral	0.365
BRCA1	P38398-1.2	K109G	Pathogenic	0.74
BRCA1	P38398-1.2	K109H	Neutral	0.294
BRCA1	P38398-1.2	K109I	Neutral	0.423
BRCA1	P38398-1.2	K109L	Neutral	0.338
BRCA1	P38398-1.2	K109M	Neutral	0.263
BRCA1	P38398-1.2	K109N	Neutral	0.324
BRCA1	P38398-1.2	K109P	Neutral	0.435
BRCA1	P38398-1.2	K109Q	Neutral	0.181
BRCA1	P38398-1.2	K109R	Neutral	0.116
BRCA1	P38398-1.2	K109S	Neutral	0.441
BRCA1	P38398-1.2	K109T	Neutral	0.42
BRCA1	P38398-1.2	K109V	Neutral	0.44
BRCA1	P38398-1.2	K109W	Pathogenic	0.514
BRCA1	P38398-1.2	K109Y	Neutral	0.316
BRCA1	P38398-1.2	K110A	Neutral	0.496
BRCA1	P38398-1.2	K110C	Pathogenic	0.569
BRCA1	P38398-1.2	K110D	Neutral	0.371
BRCA1	P38398-1.2	K110E	Neutral	0.16
BRCA1	P38398-1.2	K110F	Neutral	0.304
BRCA1	P38398-1.2	K110G	Pathogenic	0.685
BRCA1	P38398-1.2	K110H	Neutral	0.241
BRCA1	P38398-1.2	K110I	Neutral	0.358
BRCA1	P38398-1.2	K110L	Neutral	0.28
BRCA1	P38398-1.2	K110M	Neutral	0.214
BRCA1	P38398-1.2	K110N	Neutral	0.268
BRCA1	P38398-1.2	K110P	Neutral	0.369
BRCA1	P38398-1.2	K110Q	Neutral	0.144
BRCA1	P38398-1.2	K110R	Neutral	0.091
BRCA1	P38398-1.2	K110S	Neutral	0.376
BRCA1	P38398-1.2	K110T	Neutral	0.356
BRCA1	P38398-1.2	K110V	Neutral	0.374
BRCA1	P38398-1.2	K110W	Neutral	0.447
BRCA1	P38398-1.2	K110Y	Neutral	0.261
BRCA1	P38398-1.2	E111A	Neutral	0.07
BRCA1	P38398-1.2	E111C	Neutral	0.126
BRCA1	P38398-1.2	E111D	Neutral	0.015
BRCA1	P38398-1.2	E111F	Neutral	0.096
BRCA1	P38398-1.2	E111G	Neutral	0.142
BRCA1	P38398-1.2	E111H	Neutral	0.024
BRCA1	P38398-1.2	E111I	Neutral	0.076
BRCA1	P38398-1.2	E111K	Neutral	0.025
BRCA1	P38398-1.2	E111L	Neutral	0.077
BRCA1	P38398-1.2	E111M	Neutral	0.055
BRCA1	P38398-1.2	E111N	Neutral	0.027
BRCA1	P38398-1.2	E111P	Neutral	0.043
BRCA1	P38398-1.2	E111Q	Neutral	0.011
BRCA1	P38398-1.2	E111R	Neutral	0.047
BRCA1	P38398-1.2	E111S	Neutral	0.044
BRCA1	P38398-1.2	E111T	Neutral	0.04
BRCA1	P38398-1.2	E111V	Neutral	0.044
BRCA1	P38398-1.2	E111W	Neutral	0.163
BRCA1	P38398-1.2	E111Y	Neutral	0.079
BRCA1	P38398-1.2	N112A	Neutral	0.122
BRCA1	P38398-1.2	N112C	Neutral	0.115
BRCA1	P38398-1.2	N112D	Neutral	0.027
BRCA1	P38398-1.2	N112E	Neutral	0.046
BRCA1	P38398-1.2	N112F	Neutral	0.195
BRCA1	P38398-1.2	N112G	Neutral	0.093
BRCA1	P38398-1.2	N112H	Neutral	0.038
BRCA1	P38398-1.2	N112I	Neutral	0.16
BRCA1	P38398-1.2	N112K	Neutral	0.078
BRCA1	P38398-1.2	N112L	Neutral	0.16
BRCA1	P38398-1.2	N112M	Neutral	0.118
BRCA1	P38398-1.2	N112P	Neutral	0.076
BRCA1	P38398-1.2	N112Q	Neutral	0.05
BRCA1	P38398-1.2	N112R	Neutral	0.101
BRCA1	P38398-1.2	N112S	Neutral	0.039
BRCA1	P38398-1.2	N112T	Neutral	0.036
BRCA1	P38398-1.2	N112V	Neutral	0.112
BRCA1	P38398-1.2	N112W	Neutral	0.392
BRCA1	P38398-1.2	N112Y	Neutral	0.164
BRCA1	P38398-1.2	N113A	Neutral	0.042
BRCA1	P38398-1.2	N113C	Neutral	0.039
BRCA1	P38398-1.2	N113D	Neutral	0.009
BRCA1	P38398-1.2	N113E	Neutral	0.015
BRCA1	P38398-1.2	N113F	Neutral	0.072
BRCA1	P38398-1.2	N113G	Neutral	0.032
BRCA1	P38398-1.2	N113H	Neutral	0.013
BRCA1	P38398-1.2	N113I	Neutral	0.057
BRCA1	P38398-1.2	N113K	Neutral	0.026
BRCA1	P38398-1.2	N113L	Neutral	0.057
BRCA1	P38398-1.2	N113M	Neutral	0.041
BRCA1	P38398-1.2	N113P	Neutral	0.026
BRCA1	P38398-1.2	N113Q	Neutral	0.017
BRCA1	P38398-1.2	N113R	Neutral	0.035
BRCA1	P38398-1.2	N113S	Neutral	0.013
BRCA1	P38398-1.2	N113T	Neutral	0.012
BRCA1	P38398-1.2	N113V	Neutral	0.038
BRCA1	P38398-1.2	N113W	Neutral	0.17
BRCA1	P38398-1.2	N113Y	Neutral	0.059
BRCA1	P38398-1.2	S114A	Neutral	0.086
BRCA1	P38398-1.2	S114C	Neutral	0.184
BRCA1	P38398-1.2	S114D	Neutral	0.15
BRCA1	P38398-1.2	S114E	Neutral	0.208
BRCA1	P38398-1.2	S114F	Neutral	0.487
BRCA1	P38398-1.2	S114G	Neutral	0.172
BRCA1	P38398-1.2	S114H	Neutral	0.318
BRCA1	P38398-1.2	S114I	Neutral	0.426
BRCA1	P38398-1.2	S114K	Neutral	0.318
BRCA1	P38398-1.2	S114L	Neutral	0.427
BRCA1	P38398-1.2	S114M	Neutral	0.343
BRCA1	P38398-1.2	S114N	Neutral	0.121
BRCA1	P38398-1.2	S114P	Neutral	0.198
BRCA1	P38398-1.2	S114Q	Neutral	0.229
BRCA1	P38398-1.2	S114R	Neutral	0.472
BRCA1	P38398-1.2	S114T	Neutral	0.114
BRCA1	P38398-1.2	S114V	Neutral	0.33
BRCA1	P38398-1.2	S114W	Pathogenic	0.716
BRCA1	P38398-1.2	S114Y	Pathogenic	0.524
BRCA1	P38398-1.2	P115A	Neutral	0.131
BRCA1	P38398-1.2	P115C	Neutral	0.171
BRCA1	P38398-1.2	P115D	Neutral	0.083
BRCA1	P38398-1.2	P115E	Neutral	0.12
BRCA1	P38398-1.2	P115F	Neutral	0.42
BRCA1	P38398-1.2	P115G	Neutral	0.248
BRCA1	P38398-1.2	P115H	Neutral	0.195
BRCA1	P38398-1.2	P115I	Neutral	0.283
BRCA1	P38398-1.2	P115K	Neutral	0.194
BRCA1	P38398-1.2	P115L	Neutral	0.283
BRCA1	P38398-1.2	P115M	Neutral	0.217
BRCA1	P38398-1.2	P115N	Neutral	0.128
BRCA1	P38398-1.2	P115Q	Neutral	0.133
BRCA1	P38398-1.2	P115R	Neutral	0.316
BRCA1	P38398-1.2	P115S	Neutral	0.116
BRCA1	P38398-1.2	P115T	Neutral	0.088
BRCA1	P38398-1.2	P115V	Neutral	0.154
BRCA1	P38398-1.2	P115W	Pathogenic	0.572
BRCA1	P38398-1.2	P115Y	Neutral	0.369
BRCA1	P38398-1.2	E116A	Neutral	0.484
BRCA1	P38398-1.2	E116C	Pathogenic	0.644
BRCA1	P38398-1.2	E116D	Neutral	0.158
BRCA1	P38398-1.2	E116F	Pathogenic	0.57
BRCA1	P38398-1.2	E116G	Pathogenic	0.675
BRCA1	P38398-1.2	E116H	Neutral	0.239
BRCA1	P38398-1.2	E116I	Pathogenic	0.509
BRCA1	P38398-1.2	E116K	Neutral	0.243
BRCA1	P38398-1.2	E116L	Pathogenic	0.51
BRCA1	P38398-1.2	E116M	Neutral	0.421
BRCA1	P38398-1.2	E116N	Neutral	0.258
BRCA1	P38398-1.2	E116P	Neutral	0.358
BRCA1	P38398-1.2	E116Q	Neutral	0.123
BRCA1	P38398-1.2	E116R	Neutral	0.382
BRCA1	P38398-1.2	E116S	Neutral	0.365
BRCA1	P38398-1.2	E116T	Neutral	0.345
BRCA1	P38398-1.2	E116V	Neutral	0.363
BRCA1	P38398-1.2	E116W	Pathogenic	0.71
BRCA1	P38398-1.2	E116Y	Pathogenic	0.516
BRCA1	P38398-1.2	H117A	Neutral	0.127
BRCA1	P38398-1.2	H117C	Neutral	0.119
BRCA1	P38398-1.2	H117D	Neutral	0.055
BRCA1	P38398-1.2	H117E	Neutral	0.027
BRCA1	P38398-1.2	H117F	Neutral	0.044
BRCA1	P38398-1.2	H117G	Neutral	0.182
BRCA1	P38398-1.2	H117I	Neutral	0.07
BRCA1	P38398-1.2	H117K	Neutral	0.045
BRCA1	P38398-1.2	H117L	Neutral	0.07
BRCA1	P38398-1.2	H117M	Neutral	0.05
BRCA1	P38398-1.2	H117N	Neutral	0.025
BRCA1	P38398-1.2	H117P	Neutral	0.08
BRCA1	P38398-1.2	H117Q	Neutral	0.024
BRCA1	P38398-1.2	H117R	Neutral	0.041
BRCA1	P38398-1.2	H117S	Neutral	0.081
BRCA1	P38398-1.2	H117T	Neutral	0.076
BRCA1	P38398-1.2	H117V	Neutral	0.081
BRCA1	P38398-1.2	H117W	Neutral	0.109
BRCA1	P38398-1.2	H117Y	Neutral	0.018
BRCA1	P38398-1.2	L118A	Neutral	0.081
BRCA1	P38398-1.2	L118C	Neutral	0.055
BRCA1	P38398-1.2	L118D	Neutral	0.131
BRCA1	P38398-1.2	L118E	Neutral	0.066
BRCA1	P38398-1.2	L118F	Neutral	0.022
BRCA1	P38398-1.2	L118G	Neutral	0.284
BRCA1	P38398-1.2	L118H	Neutral	0.055
BRCA1	P38398-1.2	L118I	Neutral	0.008
BRCA1	P38398-1.2	L118K	Neutral	0.043
BRCA1	P38398-1.2	L118M	Neutral	0.008
BRCA1	P38398-1.2	L118N	Neutral	0.086
BRCA1	P38398-1.2	L118P	Neutral	0.099
BRCA1	P38398-1.2	L118Q	Neutral	0.042
BRCA1	P38398-1.2	L118R	Neutral	0.056
BRCA1	P38398-1.2	L118S	Neutral	0.099
BRCA1	P38398-1.2	L118T	Neutral	0.047
BRCA1	P38398-1.2	L118V	Neutral	0.018
BRCA1	P38398-1.2	L118W	Neutral	0.079
BRCA1	P38398-1.2	L118Y	Neutral	0.035
BRCA1	P38398-1.2	K119A	Neutral	0.151
BRCA1	P38398-1.2	K119C	Neutral	0.193
BRCA1	P38398-1.2	K119D	Neutral	0.097
BRCA1	P38398-1.2	K119E	Neutral	0.033
BRCA1	P38398-1.2	K119F	Neutral	0.074
BRCA1	P38398-1.2	K119G	Neutral	0.283
BRCA1	P38398-1.2	K119H	Neutral	0.055
BRCA1	P38398-1.2	K119I	Neutral	0.092
BRCA1	P38398-1.2	K119L	Neutral	0.066
BRCA1	P38398-1.2	K119M	Neutral	0.047
BRCA1	P38398-1.2	K119N	Neutral	0.062
BRCA1	P38398-1.2	K119P	Neutral	0.096
BRCA1	P38398-1.2	K119Q	Neutral	0.03
BRCA1	P38398-1.2	K119R	Neutral	0.018
BRCA1	P38398-1.2	K119S	Neutral	0.099
BRCA1	P38398-1.2	K119T	Neutral	0.091
BRCA1	P38398-1.2	K119V	Neutral	0.098
BRCA1	P38398-1.2	K119W	Neutral	0.128
BRCA1	P38398-1.2	K119Y	Neutral	0.06
BRCA1	P38398-1.2	D120A	Neutral	0.15
BRCA1	P38398-1.2	D120C	Neutral	0.141
BRCA1	P38398-1.2	D120E	Neutral	0.035
BRCA1	P38398-1.2	D120F	Neutral	0.277
BRCA1	P38398-1.2	D120G	Neutral	0.158
BRCA1	P38398-1.2	D120H	Neutral	0.116
BRCA1	P38398-1.2	D120I	Neutral	0.231
BRCA1	P38398-1.2	D120K	Neutral	0.162
BRCA1	P38398-1.2	D120L	Neutral	0.302
BRCA1	P38398-1.2	D120M	Neutral	0.233
BRCA1	P38398-1.2	D120N	Neutral	0.038
BRCA1	P38398-1.2	D120P	Neutral	0.068
BRCA1	P38398-1.2	D120Q	Neutral	0.078
BRCA1	P38398-1.2	D120R	Neutral	0.271
BRCA1	P38398-1.2	D120S	Neutral	0.07
BRCA1	P38398-1.2	D120T	Neutral	0.07
BRCA1	P38398-1.2	D120V	Neutral	0.166
BRCA1	P38398-1.2	D120W	Pathogenic	0.505
BRCA1	P38398-1.2	D120Y	Neutral	0.308
BRCA1	P38398-1.2	E121A	Pathogenic	0.637
BRCA1	P38398-1.2	E121C	Pathogenic	0.772
BRCA1	P38398-1.2	E121D	Neutral	0.259
BRCA1	P38398-1.2	E121F	Pathogenic	0.712
BRCA1	P38398-1.2	E121G	Pathogenic	0.795
BRCA1	P38398-1.2	E121H	Neutral	0.37
BRCA1	P38398-1.2	E121I	Pathogenic	0.659
BRCA1	P38398-1.2	E121K	Neutral	0.375
BRCA1	P38398-1.2	E121L	Pathogenic	0.66
BRCA1	P38398-1.2	E121M	Pathogenic	0.576
BRCA1	P38398-1.2	E121N	Neutral	0.394
BRCA1	P38398-1.2	E121P	Pathogenic	0.511
BRCA1	P38398-1.2	E121Q	Neutral	0.207
BRCA1	P38398-1.2	E121R	Pathogenic	0.535
BRCA1	P38398-1.2	E121S	Pathogenic	0.518
BRCA1	P38398-1.2	E121T	Neutral	0.496
BRCA1	P38398-1.2	E121V	Pathogenic	0.516
BRCA1	P38398-1.2	E121W	Pathogenic	0.82
BRCA1	P38398-1.2	E121Y	Pathogenic	0.666
BRCA1	P38398-1.2	V122A	Neutral	0.032
BRCA1	P38398-1.2	V122C	Neutral	0.03
BRCA1	P38398-1.2	V122D	Neutral	0.053
BRCA1	P38398-1.2	V122E	Neutral	0.03
BRCA1	P38398-1.2	V122F	Neutral	0.038
BRCA1	P38398-1.2	V122G	Neutral	0.128
BRCA1	P38398-1.2	V122H	Neutral	0.053
BRCA1	P38398-1.2	V122I	Neutral	0.007
BRCA1	P38398-1.2	V122K	Neutral	0.052
BRCA1	P38398-1.2	V122L	Neutral	0.015
BRCA1	P38398-1.2	V122M	Neutral	0.015
BRCA1	P38398-1.2	V122N	Neutral	0.048
BRCA1	P38398-1.2	V122P	Neutral	0.039
BRCA1	P38398-1.2	V122Q	Neutral	0.034
BRCA1	P38398-1.2	V122R	Neutral	0.096
BRCA1	P38398-1.2	V122S	Neutral	0.055
BRCA1	P38398-1.2	V122T	Neutral	0.018
BRCA1	P38398-1.2	V122W	Neutral	0.131
BRCA1	P38398-1.2	V122Y	Neutral	0.043
BRCA1	P38398-1.2	S123A	Neutral	0.116
BRCA1	P38398-1.2	S123C	Neutral	0.238
BRCA1	P38398-1.2	S123D	Neutral	0.196
BRCA1	P38398-1.2	S123E	Neutral	0.267
BRCA1	P38398-1.2	S123F	Pathogenic	0.568
BRCA1	P38398-1.2	S123G	Neutral	0.224
BRCA1	P38398-1.2	S123H	Neutral	0.393
BRCA1	P38398-1.2	S123I	Pathogenic	0.507
BRCA1	P38398-1.2	S123K	Neutral	0.392
BRCA1	P38398-1.2	S123L	Pathogenic	0.508
BRCA1	P38398-1.2	S123M	Neutral	0.42
BRCA1	P38398-1.2	S123N	Neutral	0.16
BRCA1	P38398-1.2	S123P	Neutral	0.256
BRCA1	P38398-1.2	S123Q	Neutral	0.291
BRCA1	P38398-1.2	S123R	Pathogenic	0.554
BRCA1	P38398-1.2	S123T	Neutral	0.152
BRCA1	P38398-1.2	S123V	Neutral	0.406
BRCA1	P38398-1.2	S123W	Pathogenic	0.777
BRCA1	P38398-1.2	S123Y	Pathogenic	0.604
BRCA1	P38398-1.2	I124A	Neutral	0.161
BRCA1	P38398-1.2	I124C	Neutral	0.113
BRCA1	P38398-1.2	I124D	Neutral	0.186
BRCA1	P38398-1.2	I124E	Neutral	0.133
BRCA1	P38398-1.2	I124F	Neutral	0.047
BRCA1	P38398-1.2	I124G	Neutral	0.465
BRCA1	P38398-1.2	I124H	Neutral	0.113
BRCA1	P38398-1.2	I124K	Neutral	0.123
BRCA1	P38398-1.2	I124L	Neutral	0.018
BRCA1	P38398-1.2	I124M	Neutral	0.026
BRCA1	P38398-1.2	I124N	Neutral	0.17
BRCA1	P38398-1.2	I124P	Neutral	0.194
BRCA1	P38398-1.2	I124Q	Neutral	0.122
BRCA1	P38398-1.2	I124R	Neutral	0.157
BRCA1	P38398-1.2	I124S	Neutral	0.194
BRCA1	P38398-1.2	I124T	Neutral	0.097
BRCA1	P38398-1.2	I124V	Neutral	0.019
BRCA1	P38398-1.2	I124W	Neutral	0.214
BRCA1	P38398-1.2	I124Y	Neutral	0.074
BRCA1	P38398-1.2	I125A	Pathogenic	0.858
BRCA1	P38398-1.2	I125C	Pathogenic	0.8
BRCA1	P38398-1.2	I125D	Pathogenic	0.878
BRCA1	P38398-1.2	I125E	Pathogenic	0.828
BRCA1	P38398-1.2	I125F	Pathogenic	0.608
BRCA1	P38398-1.2	I125G	Pathogenic	0.965
BRCA1	P38398-1.2	I125H	Pathogenic	0.801
BRCA1	P38398-1.2	I125K	Pathogenic	0.814
BRCA1	P38398-1.2	I125L	Neutral	0.37
BRCA1	P38398-1.2	I125M	Neutral	0.455
BRCA1	P38398-1.2	I125N	Pathogenic	0.866
BRCA1	P38398-1.2	I125P	Pathogenic	0.883
BRCA1	P38398-1.2	I125Q	Pathogenic	0.813
BRCA1	P38398-1.2	I125R	Pathogenic	0.854
BRCA1	P38398-1.2	I125S	Pathogenic	0.883
BRCA1	P38398-1.2	I125T	Pathogenic	0.772
BRCA1	P38398-1.2	I125V	Neutral	0.381
BRCA1	P38398-1.2	I125W	Pathogenic	0.895
BRCA1	P38398-1.2	I125Y	Pathogenic	0.715
BRCA1	P38398-1.2	Q126A	Pathogenic	0.772
BRCA1	P38398-1.2	Q126C	Pathogenic	0.82
BRCA1	P38398-1.2	Q126D	Pathogenic	0.58
BRCA1	P38398-1.2	Q126E	Neutral	0.31
BRCA1	P38398-1.2	Q126F	Pathogenic	0.793
BRCA1	P38398-1.2	Q126G	Pathogenic	0.882
BRCA1	P38398-1.2	Q126H	Neutral	0.476
BRCA1	P38398-1.2	Q126I	Pathogenic	0.75
BRCA1	P38398-1.2	Q126K	Neutral	0.478
BRCA1	P38398-1.2	Q126L	Pathogenic	0.676
BRCA1	P38398-1.2	Q126M	Pathogenic	0.504
BRCA1	P38398-1.2	Q126N	Pathogenic	0.554
BRCA1	P38398-1.2	Q126P	Pathogenic	0.669
BRCA1	P38398-1.2	Q126R	Pathogenic	0.55
BRCA1	P38398-1.2	Q126S	Pathogenic	0.675
BRCA1	P38398-1.2	Q126T	Pathogenic	0.656
BRCA1	P38398-1.2	Q126V	Pathogenic	0.673
BRCA1	P38398-1.2	Q126W	Pathogenic	0.831
BRCA1	P38398-1.2	Q126Y	Pathogenic	0.682
BRCA1	P38398-1.2	S127A	Neutral	0.336
BRCA1	P38398-1.2	S127C	Pathogenic	0.548
BRCA1	P38398-1.2	S127D	Neutral	0.486
BRCA1	P38398-1.2	S127E	Pathogenic	0.586
BRCA1	P38398-1.2	S127F	Pathogenic	0.836
BRCA1	P38398-1.2	S127G	Pathogenic	0.528
BRCA1	P38398-1.2	S127H	Pathogenic	0.715
BRCA1	P38398-1.2	S127I	Pathogenic	0.8
BRCA1	P38398-1.2	S127K	Pathogenic	0.714
BRCA1	P38398-1.2	S127L	Pathogenic	0.8
BRCA1	P38398-1.2	S127M	Pathogenic	0.737
BRCA1	P38398-1.2	S127N	Neutral	0.424
BRCA1	P38398-1.2	S127P	Pathogenic	0.571
BRCA1	P38398-1.2	S127Q	Pathogenic	0.614
BRCA1	P38398-1.2	S127R	Pathogenic	0.828
BRCA1	P38398-1.2	S127T	Neutral	0.409
BRCA1	P38398-1.2	S127V	Pathogenic	0.726
BRCA1	P38398-1.2	S127W	Pathogenic	0.931
BRCA1	P38398-1.2	S127Y	Pathogenic	0.855
BRCA1	P38398-1.2	M128A	Neutral	0.186
BRCA1	P38398-1.2	M128C	Neutral	0.132
BRCA1	P38398-1.2	M128D	Neutral	0.214
BRCA1	P38398-1.2	M128E	Neutral	0.113
BRCA1	P38398-1.2	M128F	Neutral	0.054
BRCA1	P38398-1.2	M128G	Neutral	0.417
BRCA1	P38398-1.2	M128H	Neutral	0.095
BRCA1	P38398-1.2	M128I	Neutral	0.03
BRCA1	P38398-1.2	M128K	Neutral	0.074
BRCA1	P38398-1.2	M128L	Neutral	0.021
BRCA1	P38398-1.2	M128N	Neutral	0.145
BRCA1	P38398-1.2	M128P	Neutral	0.166
BRCA1	P38398-1.2	M128Q	Neutral	0.052
BRCA1	P38398-1.2	M128R	Neutral	0.097
BRCA1	P38398-1.2	M128S	Neutral	0.166
BRCA1	P38398-1.2	M128T	Neutral	0.113
BRCA1	P38398-1.2	M128V	Neutral	0.046
BRCA1	P38398-1.2	M128W	Neutral	0.132
BRCA1	P38398-1.2	M128Y	Neutral	0.087
BRCA1	P38398-1.2	G129A	Pathogenic	0.694
BRCA1	P38398-1.2	G129C	Pathogenic	0.911
BRCA1	P38398-1.2	G129D	Pathogenic	0.846
BRCA1	P38398-1.2	G129E	Pathogenic	0.922
BRCA1	P38398-1.2	G129F	Pathogenic	0.967
BRCA1	P38398-1.2	G129H	Pathogenic	0.936
BRCA1	P38398-1.2	G129I	Pathogenic	0.971
BRCA1	P38398-1.2	G129K	Pathogenic	0.955
BRCA1	P38398-1.2	G129L	Pathogenic	0.971
BRCA1	P38398-1.2	G129M	Pathogenic	0.959
BRCA1	P38398-1.2	G129N	Pathogenic	0.811
BRCA1	P38398-1.2	G129P	Pathogenic	0.886
BRCA1	P38398-1.2	G129Q	Pathogenic	0.93
BRCA1	P38398-1.2	G129R	Pathogenic	0.966
BRCA1	P38398-1.2	G129S	Pathogenic	0.723
BRCA1	P38398-1.2	G129T	Pathogenic	0.893
BRCA1	P38398-1.2	G129V	Pathogenic	0.939
BRCA1	P38398-1.2	G129W	Pathogenic	0.974
BRCA1	P38398-1.2	G129Y	Pathogenic	0.972
BRCA1	P38398-1.2	Y130A	Pathogenic	0.905
BRCA1	P38398-1.2	Y130C	Pathogenic	0.864
BRCA1	P38398-1.2	Y130D	Pathogenic	0.888
BRCA1	P38398-1.2	Y130E	Pathogenic	0.787
BRCA1	P38398-1.2	Y130F	Neutral	0.254
BRCA1	P38398-1.2	Y130G	Pathogenic	0.954
BRCA1	P38398-1.2	Y130H	Neutral	0.417
BRCA1	P38398-1.2	Y130I	Pathogenic	0.651
BRCA1	P38398-1.2	Y130K	Pathogenic	0.673
BRCA1	P38398-1.2	Y130L	Pathogenic	0.651
BRCA1	P38398-1.2	Y130M	Pathogenic	0.653
BRCA1	P38398-1.2	Y130N	Pathogenic	0.831
BRCA1	P38398-1.2	Y130P	Pathogenic	0.893
BRCA1	P38398-1.2	Y130Q	Pathogenic	0.698
BRCA1	P38398-1.2	Y130R	Pathogenic	0.678
BRCA1	P38398-1.2	Y130S	Pathogenic	0.892
BRCA1	P38398-1.2	Y130T	Pathogenic	0.843
BRCA1	P38398-1.2	Y130V	Pathogenic	0.742
BRCA1	P38398-1.2	Y130W	Neutral	0.409
BRCA1	P38398-1.2	R131A	Pathogenic	0.927
BRCA1	P38398-1.2	R131C	Pathogenic	0.945
BRCA1	P38398-1.2	R131D	Pathogenic	0.917
BRCA1	P38398-1.2	R131E	Pathogenic	0.78
BRCA1	P38398-1.2	R131F	Pathogenic	0.85
BRCA1	P38398-1.2	R131G	Pathogenic	0.966
BRCA1	P38398-1.2	R131H	Pathogenic	0.741
BRCA1	P38398-1.2	R131I	Pathogenic	0.878
BRCA1	P38398-1.2	R131K	Neutral	0.492
BRCA1	P38398-1.2	R131L	Pathogenic	0.834
BRCA1	P38398-1.2	R131M	Pathogenic	0.779
BRCA1	P38398-1.2	R131N	Pathogenic	0.826
BRCA1	P38398-1.2	R131P	Pathogenic	0.916
BRCA1	P38398-1.2	R131Q	Pathogenic	0.686
BRCA1	P38398-1.2	R131S	Pathogenic	0.918
BRCA1	P38398-1.2	R131T	Pathogenic	0.877
BRCA1	P38398-1.2	R131V	Pathogenic	0.918
BRCA1	P38398-1.2	R131W	Pathogenic	0.854
BRCA1	P38398-1.2	R131Y	Pathogenic	0.778
BRCA1	P38398-1.2	N132A	Pathogenic	0.613
BRCA1	P38398-1.2	N132C	Pathogenic	0.596
BRCA1	P38398-1.2	N132D	Neutral	0.24
BRCA1	P38398-1.2	N132E	Neutral	0.353
BRCA1	P38398-1.2	N132F	Pathogenic	0.734
BRCA1	P38398-1.2	N132G	Pathogenic	0.54
BRCA1	P38398-1.2	N132H	Neutral	0.313
BRCA1	P38398-1.2	N132I	Pathogenic	0.684
BRCA1	P38398-1.2	N132K	Neutral	0.491
BRCA1	P38398-1.2	N132L	Pathogenic	0.685
BRCA1	P38398-1.2	N132M	Pathogenic	0.603
BRCA1	P38398-1.2	N132P	Neutral	0.485
BRCA1	P38398-1.2	N132Q	Neutral	0.377
BRCA1	P38398-1.2	N132R	Pathogenic	0.563
BRCA1	P38398-1.2	N132S	Neutral	0.319
BRCA1	P38398-1.2	N132T	Neutral	0.3
BRCA1	P38398-1.2	N132V	Pathogenic	0.589
BRCA1	P38398-1.2	N132W	Pathogenic	0.88
BRCA1	P38398-1.2	N132Y	Pathogenic	0.69
BRCA1	P38398-1.2	R133A	Pathogenic	0.927
BRCA1	P38398-1.2	R133C	Pathogenic	0.945
BRCA1	P38398-1.2	R133D	Pathogenic	0.917
BRCA1	P38398-1.2	R133E	Pathogenic	0.78
BRCA1	P38398-1.2	R133F	Pathogenic	0.85
BRCA1	P38398-1.2	R133G	Pathogenic	0.966
BRCA1	P38398-1.2	R133H	Pathogenic	0.741
BRCA1	P38398-1.2	R133I	Pathogenic	0.878
BRCA1	P38398-1.2	R133K	Neutral	0.492
BRCA1	P38398-1.2	R133L	Pathogenic	0.834
BRCA1	P38398-1.2	R133M	Pathogenic	0.779
BRCA1	P38398-1.2	R133N	Pathogenic	0.826
BRCA1	P38398-1.2	R133P	Pathogenic	0.916
BRCA1	P38398-1.2	R133Q	Pathogenic	0.686
BRCA1	P38398-1.2	R133S	Pathogenic	0.918
BRCA1	P38398-1.2	R133T	Pathogenic	0.877
BRCA1	P38398-1.2	R133V	Pathogenic	0.918
BRCA1	P38398-1.2	R133W	Pathogenic	0.854
BRCA1	P38398-1.2	R133Y	Pathogenic	0.778
BRCA1	P38398-1.2	A134C	Neutral	0.031
BRCA1	P38398-1.2	A134D	Neutral	0.069
BRCA1	P38398-1.2	A134E	Neutral	0.072
BRCA1	P38398-1.2	A134F	Neutral	0.164
BRCA1	P38398-1.2	A134G	Neutral	0.032
BRCA1	P38398-1.2	A134H	Neutral	0.121
BRCA1	P38398-1.2	A134I	Neutral	0.097
BRCA1	P38398-1.2	A134K	Neutral	0.121
BRCA1	P38398-1.2	A134L	Neutral	0.097
BRCA1	P38398-1.2	A134M	Neutral	0.098
BRCA1	P38398-1.2	A134N	Neutral	0.077
BRCA1	P38398-1.2	A134P	Neutral	0.049
BRCA1	P38398-1.2	A134Q	Neutral	0.08
BRCA1	P38398-1.2	A134R	Neutral	0.155
BRCA1	P38398-1.2	A134S	Neutral	0.017
BRCA1	P38398-1.2	A134T	Neutral	0.037
BRCA1	P38398-1.2	A134V	Neutral	0.047
BRCA1	P38398-1.2	A134W	Neutral	0.343
BRCA1	P38398-1.2	A134Y	Neutral	0.186
BRCA1	P38398-1.2	K135A	Neutral	0.388
BRCA1	P38398-1.2	K135C	Neutral	0.459
BRCA1	P38398-1.2	K135D	Neutral	0.275
BRCA1	P38398-1.2	K135E	Neutral	0.109
BRCA1	P38398-1.2	K135F	Neutral	0.22
BRCA1	P38398-1.2	K135G	Pathogenic	0.583
BRCA1	P38398-1.2	K135H	Neutral	0.17
BRCA1	P38398-1.2	K135I	Neutral	0.264
BRCA1	P38398-1.2	K135L	Neutral	0.2
BRCA1	P38398-1.2	K135M	Neutral	0.149
BRCA1	P38398-1.2	K135N	Neutral	0.19
BRCA1	P38398-1.2	K135P	Neutral	0.274
BRCA1	P38398-1.2	K135Q	Neutral	0.098
BRCA1	P38398-1.2	K135R	Neutral	0.06
BRCA1	P38398-1.2	K135S	Neutral	0.279
BRCA1	P38398-1.2	K135T	Neutral	0.262
BRCA1	P38398-1.2	K135V	Neutral	0.278
BRCA1	P38398-1.2	K135W	Neutral	0.342
BRCA1	P38398-1.2	K135Y	Neutral	0.185
BRCA1	P38398-1.2	R136A	Pathogenic	0.626
BRCA1	P38398-1.2	R136C	Pathogenic	0.692
BRCA1	P38398-1.2	R136D	Pathogenic	0.591
BRCA1	P38398-1.2	R136E	Neutral	0.318
BRCA1	P38398-1.2	R136F	Neutral	0.427
BRCA1	P38398-1.2	R136G	Pathogenic	0.787
BRCA1	P38398-1.2	R136H	Neutral	0.274
BRCA1	P38398-1.2	R136I	Neutral	0.487
BRCA1	P38398-1.2	R136K	Neutral	0.113
BRCA1	P38398-1.2	R136L	Neutral	0.398
BRCA1	P38398-1.2	R136M	Neutral	0.317
BRCA1	P38398-1.2	R136N	Neutral	0.384
BRCA1	P38398-1.2	R136P	Pathogenic	0.59
BRCA1	P38398-1.2	R136Q	Neutral	0.224
BRCA1	P38398-1.2	R136S	Pathogenic	0.596
BRCA1	P38398-1.2	R136T	Neutral	0.485
BRCA1	P38398-1.2	R136V	Pathogenic	0.595
BRCA1	P38398-1.2	R136W	Neutral	0.436
BRCA1	P38398-1.2	R136Y	Neutral	0.315
BRCA1	P38398-1.2	L137A	Neutral	0.14
BRCA1	P38398-1.2	L137C	Neutral	0.098
BRCA1	P38398-1.2	L137D	Neutral	0.218
BRCA1	P38398-1.2	L137E	Neutral	0.115
BRCA1	P38398-1.2	L137F	Neutral	0.04
BRCA1	P38398-1.2	L137G	Neutral	0.424
BRCA1	P38398-1.2	L137H	Neutral	0.098
BRCA1	P38398-1.2	L137I	Neutral	0.016
BRCA1	P38398-1.2	L137K	Neutral	0.076
BRCA1	P38398-1.2	L137M	Neutral	0.015
BRCA1	P38398-1.2	L137N	Neutral	0.148
BRCA1	P38398-1.2	L137P	Neutral	0.169
BRCA1	P38398-1.2	L137Q	Neutral	0.075
BRCA1	P38398-1.2	L137R	Neutral	0.099
BRCA1	P38398-1.2	L137S	Neutral	0.169
BRCA1	P38398-1.2	L137T	Neutral	0.084
BRCA1	P38398-1.2	L137V	Neutral	0.033
BRCA1	P38398-1.2	L137W	Neutral	0.138
BRCA1	P38398-1.2	L137Y	Neutral	0.063
BRCA1	P38398-1.2	L138A	Neutral	0.014
BRCA1	P38398-1.2	L138C	Neutral	0.01
BRCA1	P38398-1.2	L138D	Neutral	0.024
BRCA1	P38398-1.2	L138E	Neutral	0.012
BRCA1	P38398-1.2	L138F	Neutral	0.004
BRCA1	P38398-1.2	L138G	Neutral	0.062
BRCA1	P38398-1.2	L138H	Neutral	0.01
BRCA1	P38398-1.2	L138I	Neutral	0.001
BRCA1	P38398-1.2	L138K	Neutral	0.007
BRCA1	P38398-1.2	L138M	Neutral	0.001
BRCA1	P38398-1.2	L138N	Neutral	0.015
BRCA1	P38398-1.2	L138P	Neutral	0.018
BRCA1	P38398-1.2	L138Q	Neutral	0.007
BRCA1	P38398-1.2	L138R	Neutral	0.01
BRCA1	P38398-1.2	L138S	Neutral	0.018
BRCA1	P38398-1.2	L138T	Neutral	0.008
BRCA1	P38398-1.2	L138V	Neutral	0.003
BRCA1	P38398-1.2	L138W	Neutral	0.014
BRCA1	P38398-1.2	L138Y	Neutral	0.006
BRCA1	P38398-1.2	Q139A	Neutral	0.195
BRCA1	P38398-1.2	Q139C	Neutral	0.245
BRCA1	P38398-1.2	Q139D	Neutral	0.09
BRCA1	P38398-1.2	Q139E	Neutral	0.031
BRCA1	P38398-1.2	Q139F	Neutral	0.215
BRCA1	P38398-1.2	Q139G	Neutral	0.348
BRCA1	P38398-1.2	Q139H	Neutral	0.061
BRCA1	P38398-1.2	Q139I	Neutral	0.176
BRCA1	P38398-1.2	Q139K	Neutral	0.061
BRCA1	P38398-1.2	Q139L	Neutral	0.13
BRCA1	P38398-1.2	Q139M	Neutral	0.068
BRCA1	P38398-1.2	Q139N	Neutral	0.081
BRCA1	P38398-1.2	Q139P	Neutral	0.126
BRCA1	P38398-1.2	Q139R	Neutral	0.08
BRCA1	P38398-1.2	Q139S	Neutral	0.129
BRCA1	P38398-1.2	Q139T	Neutral	0.12
BRCA1	P38398-1.2	Q139V	Neutral	0.128
BRCA1	P38398-1.2	Q139W	Neutral	0.26
BRCA1	P38398-1.2	Q139Y	Neutral	0.133
BRCA1	P38398-1.2	S140A	Neutral	0.005
BRCA1	P38398-1.2	S140C	Neutral	0.011
BRCA1	P38398-1.2	S140D	Neutral	0.008
BRCA1	P38398-1.2	S140E	Neutral	0.013
BRCA1	P38398-1.2	S140F	Neutral	0.044
BRCA1	P38398-1.2	S140G	Neutral	0.01
BRCA1	P38398-1.2	S140H	Neutral	0.022
BRCA1	P38398-1.2	S140I	Neutral	0.035
BRCA1	P38398-1.2	S140K	Neutral	0.022
BRCA1	P38398-1.2	S140L	Neutral	0.035
BRCA1	P38398-1.2	S140M	Neutral	0.025
BRCA1	P38398-1.2	S140N	Neutral	0.007
BRCA1	P38398-1.2	S140P	Neutral	0.012
BRCA1	P38398-1.2	S140Q	Neutral	0.014
BRCA1	P38398-1.2	S140R	Neutral	0.041
BRCA1	P38398-1.2	S140T	Neutral	0.006
BRCA1	P38398-1.2	S140V	Neutral	0.023
BRCA1	P38398-1.2	S140W	Neutral	0.108
BRCA1	P38398-1.2	S140Y	Neutral	0.05
BRCA1	P38398-1.2	E141A	Pathogenic	0.589
BRCA1	P38398-1.2	E141C	Pathogenic	0.735
BRCA1	P38398-1.2	E141D	Neutral	0.223
BRCA1	P38398-1.2	E141F	Pathogenic	0.669
BRCA1	P38398-1.2	E141G	Pathogenic	0.76
BRCA1	P38398-1.2	E141H	Neutral	0.325
BRCA1	P38398-1.2	E141I	Pathogenic	0.613
BRCA1	P38398-1.2	E141K	Neutral	0.329
BRCA1	P38398-1.2	E141L	Pathogenic	0.614
BRCA1	P38398-1.2	E141M	Pathogenic	0.527
BRCA1	P38398-1.2	E141N	Neutral	0.348
BRCA1	P38398-1.2	E141P	Neutral	0.461
BRCA1	P38398-1.2	E141Q	Neutral	0.176
BRCA1	P38398-1.2	E141R	Neutral	0.485
BRCA1	P38398-1.2	E141S	Neutral	0.468
BRCA1	P38398-1.2	E141T	Neutral	0.446
BRCA1	P38398-1.2	E141V	Neutral	0.466
BRCA1	P38398-1.2	E141W	Pathogenic	0.789
BRCA1	P38398-1.2	E141Y	Pathogenic	0.62
BRCA1	P38398-1.2	P142A	Neutral	0.196
BRCA1	P38398-1.2	P142C	Neutral	0.25
BRCA1	P38398-1.2	P142D	Neutral	0.128
BRCA1	P38398-1.2	P142E	Neutral	0.18
BRCA1	P38398-1.2	P142F	Pathogenic	0.54
BRCA1	P38398-1.2	P142G	Neutral	0.348
BRCA1	P38398-1.2	P142H	Neutral	0.282
BRCA1	P38398-1.2	P142I	Neutral	0.39
BRCA1	P38398-1.2	P142K	Neutral	0.28
BRCA1	P38398-1.2	P142L	Neutral	0.39
BRCA1	P38398-1.2	P142M	Neutral	0.31
BRCA1	P38398-1.2	P142N	Neutral	0.192
BRCA1	P38398-1.2	P142Q	Neutral	0.198
BRCA1	P38398-1.2	P142R	Neutral	0.427
BRCA1	P38398-1.2	P142S	Neutral	0.175
BRCA1	P38398-1.2	P142T	Neutral	0.135
BRCA1	P38398-1.2	P142V	Neutral	0.227
BRCA1	P38398-1.2	P142W	Pathogenic	0.684
BRCA1	P38398-1.2	P142Y	Neutral	0.486
BRCA1	P38398-1.2	E143A	Neutral	0.166
BRCA1	P38398-1.2	E143C	Neutral	0.277
BRCA1	P38398-1.2	E143D	Neutral	0.038
BRCA1	P38398-1.2	E143F	Neutral	0.219
BRCA1	P38398-1.2	E143G	Neutral	0.305
BRCA1	P38398-1.2	E143H	Neutral	0.062
BRCA1	P38398-1.2	E143I	Neutral	0.18
BRCA1	P38398-1.2	E143K	Neutral	0.064
BRCA1	P38398-1.2	E143L	Neutral	0.18
BRCA1	P38398-1.2	E143M	Neutral	0.134
BRCA1	P38398-1.2	E143N	Neutral	0.069
BRCA1	P38398-1.2	E143P	Neutral	0.106
BRCA1	P38398-1.2	E143Q	Neutral	0.029
BRCA1	P38398-1.2	E143R	Neutral	0.116
BRCA1	P38398-1.2	E143S	Neutral	0.108
BRCA1	P38398-1.2	E143T	Neutral	0.1
BRCA1	P38398-1.2	E143V	Neutral	0.108
BRCA1	P38398-1.2	E143W	Neutral	0.341
BRCA1	P38398-1.2	E143Y	Neutral	0.184
BRCA1	P38398-1.2	N144A	Neutral	0.289
BRCA1	P38398-1.2	N144C	Neutral	0.275
BRCA1	P38398-1.2	N144D	Neutral	0.075
BRCA1	P38398-1.2	N144E	Neutral	0.123
BRCA1	P38398-1.2	N144F	Neutral	0.415
BRCA1	P38398-1.2	N144G	Neutral	0.231
BRCA1	P38398-1.2	N144H	Neutral	0.105
BRCA1	P38398-1.2	N144I	Neutral	0.357
BRCA1	P38398-1.2	N144K	Neutral	0.198
BRCA1	P38398-1.2	N144L	Neutral	0.358
BRCA1	P38398-1.2	N144M	Neutral	0.281
BRCA1	P38398-1.2	N144P	Neutral	0.195
BRCA1	P38398-1.2	N144Q	Neutral	0.134
BRCA1	P38398-1.2	N144R	Neutral	0.248
BRCA1	P38398-1.2	N144S	Neutral	0.107
BRCA1	P38398-1.2	N144T	Neutral	0.099
BRCA1	P38398-1.2	N144V	Neutral	0.269
BRCA1	P38398-1.2	N144W	Pathogenic	0.653
BRCA1	P38398-1.2	N144Y	Neutral	0.364
BRCA1	P38398-1.2	P145A	Neutral	0.179
BRCA1	P38398-1.2	P145C	Neutral	0.229
BRCA1	P38398-1.2	P145D	Neutral	0.116
BRCA1	P38398-1.2	P145E	Neutral	0.164
BRCA1	P38398-1.2	P145F	Pathogenic	0.512
BRCA1	P38398-1.2	P145G	Neutral	0.323
BRCA1	P38398-1.2	P145H	Neutral	0.259
BRCA1	P38398-1.2	P145I	Neutral	0.363
BRCA1	P38398-1.2	P145K	Neutral	0.258
BRCA1	P38398-1.2	P145L	Neutral	0.363
BRCA1	P38398-1.2	P145M	Neutral	0.286
BRCA1	P38398-1.2	P145N	Neutral	0.175
BRCA1	P38398-1.2	P145Q	Neutral	0.181
BRCA1	P38398-1.2	P145R	Neutral	0.4
BRCA1	P38398-1.2	P145S	Neutral	0.16
BRCA1	P38398-1.2	P145T	Neutral	0.123
BRCA1	P38398-1.2	P145V	Neutral	0.208
BRCA1	P38398-1.2	P145W	Pathogenic	0.659
BRCA1	P38398-1.2	P145Y	Neutral	0.458
BRCA1	P38398-1.2	S146A	Neutral	0.004
BRCA1	P38398-1.2	S146C	Neutral	0.01
BRCA1	P38398-1.2	S146D	Neutral	0.008
BRCA1	P38398-1.2	S146E	Neutral	0.012
BRCA1	P38398-1.2	S146F	Neutral	0.04
BRCA1	P38398-1.2	S146G	Neutral	0.009
BRCA1	P38398-1.2	S146H	Neutral	0.02
BRCA1	P38398-1.2	S146I	Neutral	0.032
BRCA1	P38398-1.2	S146K	Neutral	0.02
BRCA1	P38398-1.2	S146L	Neutral	0.032
BRCA1	P38398-1.2	S146M	Neutral	0.023
BRCA1	P38398-1.2	S146N	Neutral	0.006
BRCA1	P38398-1.2	S146P	Neutral	0.011
BRCA1	P38398-1.2	S146Q	Neutral	0.013
BRCA1	P38398-1.2	S146R	Neutral	0.038
BRCA1	P38398-1.2	S146T	Neutral	0.006
BRCA1	P38398-1.2	S146V	Neutral	0.021
BRCA1	P38398-1.2	S146W	Neutral	0.1
BRCA1	P38398-1.2	S146Y	Neutral	0.046
BRCA1	P38398-1.2	L147A	Pathogenic	0.635
BRCA1	P38398-1.2	L147C	Pathogenic	0.536
BRCA1	P38398-1.2	L147D	Pathogenic	0.748
BRCA1	P38398-1.2	L147E	Pathogenic	0.581
BRCA1	P38398-1.2	L147F	Neutral	0.308
BRCA1	P38398-1.2	L147G	Pathogenic	0.887
BRCA1	P38398-1.2	L147H	Pathogenic	0.536
BRCA1	P38398-1.2	L147I	Neutral	0.144
BRCA1	P38398-1.2	L147K	Neutral	0.467
BRCA1	P38398-1.2	L147M	Neutral	0.143
BRCA1	P38398-1.2	L147N	Pathogenic	0.65
BRCA1	P38398-1.2	L147P	Pathogenic	0.685
BRCA1	P38398-1.2	L147Q	Neutral	0.465
BRCA1	P38398-1.2	L147R	Pathogenic	0.539
BRCA1	P38398-1.2	L147S	Pathogenic	0.685
BRCA1	P38398-1.2	L147T	Neutral	0.493
BRCA1	P38398-1.2	L147V	Neutral	0.268
BRCA1	P38398-1.2	L147W	Pathogenic	0.63
BRCA1	P38398-1.2	L147Y	Neutral	0.42
BRCA1	P38398-1.2	Q148A	Pathogenic	0.611
BRCA1	P38398-1.2	Q148C	Pathogenic	0.678
BRCA1	P38398-1.2	Q148D	Neutral	0.39
BRCA1	P38398-1.2	Q148E	Neutral	0.172
BRCA1	P38398-1.2	Q148F	Pathogenic	0.64
BRCA1	P38398-1.2	Q148G	Pathogenic	0.776
BRCA1	P38398-1.2	Q148H	Neutral	0.296
BRCA1	P38398-1.2	Q148I	Pathogenic	0.582
BRCA1	P38398-1.2	Q148K	Neutral	0.298
BRCA1	P38398-1.2	Q148L	Neutral	0.492
BRCA1	P38398-1.2	Q148M	Neutral	0.32
BRCA1	P38398-1.2	Q148N	Neutral	0.365
BRCA1	P38398-1.2	Q148P	Neutral	0.483
BRCA1	P38398-1.2	Q148R	Neutral	0.361
BRCA1	P38398-1.2	Q148S	Neutral	0.49
BRCA1	P38398-1.2	Q148T	Neutral	0.469
BRCA1	P38398-1.2	Q148V	Neutral	0.489
BRCA1	P38398-1.2	Q148W	Pathogenic	0.695
BRCA1	P38398-1.2	Q148Y	Neutral	0.499
BRCA1	P38398-1.2	E149A	Neutral	0.405
BRCA1	P38398-1.2	E149C	Pathogenic	0.567
BRCA1	P38398-1.2	E149D	Neutral	0.12
BRCA1	P38398-1.2	E149F	Neutral	0.49
BRCA1	P38398-1.2	E149G	Pathogenic	0.6
BRCA1	P38398-1.2	E149H	Neutral	0.186
BRCA1	P38398-1.2	E149I	Neutral	0.429
BRCA1	P38398-1.2	E149K	Neutral	0.189
BRCA1	P38398-1.2	E149L	Neutral	0.429
BRCA1	P38398-1.2	E149M	Neutral	0.345
BRCA1	P38398-1.2	E149N	Neutral	0.202
BRCA1	P38398-1.2	E149P	Neutral	0.288
BRCA1	P38398-1.2	E149Q	Neutral	0.092
BRCA1	P38398-1.2	E149R	Neutral	0.309
BRCA1	P38398-1.2	E149S	Neutral	0.294
BRCA1	P38398-1.2	E149T	Neutral	0.276
BRCA1	P38398-1.2	E149V	Neutral	0.293
BRCA1	P38398-1.2	E149W	Pathogenic	0.639
BRCA1	P38398-1.2	E149Y	Neutral	0.436
BRCA1	P38398-1.2	T150A	Neutral	0.093
BRCA1	P38398-1.2	T150C	Neutral	0.087
BRCA1	P38398-1.2	T150D	Neutral	0.078
BRCA1	P38398-1.2	T150E	Neutral	0.104
BRCA1	P38398-1.2	T150F	Neutral	0.227
BRCA1	P38398-1.2	T150G	Neutral	0.244
BRCA1	P38398-1.2	T150H	Neutral	0.172
BRCA1	P38398-1.2	T150I	Neutral	0.138
BRCA1	P38398-1.2	T150K	Neutral	0.171
BRCA1	P38398-1.2	T150L	Neutral	0.138
BRCA1	P38398-1.2	T150M	Neutral	0.139
BRCA1	P38398-1.2	T150N	Neutral	0.057
BRCA1	P38398-1.2	T150P	Neutral	0.081
BRCA1	P38398-1.2	T150Q	Neutral	0.116
BRCA1	P38398-1.2	T150R	Neutral	0.215
BRCA1	P38398-1.2	T150S	Neutral	0.058
BRCA1	P38398-1.2	T150V	Neutral	0.069
BRCA1	P38398-1.2	T150W	Neutral	0.352
BRCA1	P38398-1.2	T150Y	Neutral	0.255
BRCA1	P38398-1.2	S151A	Neutral	0.089
BRCA1	P38398-1.2	S151C	Neutral	0.19
BRCA1	P38398-1.2	S151D	Neutral	0.155
BRCA1	P38398-1.2	S151E	Neutral	0.215
BRCA1	P38398-1.2	S151F	Neutral	0.497
BRCA1	P38398-1.2	S151G	Neutral	0.178
BRCA1	P38398-1.2	S151H	Neutral	0.327
BRCA1	P38398-1.2	S151I	Neutral	0.436
BRCA1	P38398-1.2	S151K	Neutral	0.326
BRCA1	P38398-1.2	S151L	Neutral	0.436
BRCA1	P38398-1.2	S151M	Neutral	0.352
BRCA1	P38398-1.2	S151N	Neutral	0.125
BRCA1	P38398-1.2	S151P	Neutral	0.205
BRCA1	P38398-1.2	S151Q	Neutral	0.236
BRCA1	P38398-1.2	S151R	Neutral	0.482
BRCA1	P38398-1.2	S151T	Neutral	0.118
BRCA1	P38398-1.2	S151V	Neutral	0.339
BRCA1	P38398-1.2	S151W	Pathogenic	0.724
BRCA1	P38398-1.2	S151Y	Pathogenic	0.534
BRCA1	P38398-1.2	L152A	Pathogenic	0.716
BRCA1	P38398-1.2	L152C	Pathogenic	0.626
BRCA1	P38398-1.2	L152D	Pathogenic	0.812
BRCA1	P38398-1.2	L152E	Pathogenic	0.668
BRCA1	P38398-1.2	L152F	Neutral	0.392
BRCA1	P38398-1.2	L152G	Pathogenic	0.919
BRCA1	P38398-1.2	L152H	Pathogenic	0.626
BRCA1	P38398-1.2	L152I	Neutral	0.196
BRCA1	P38398-1.2	L152K	Pathogenic	0.56
BRCA1	P38398-1.2	L152M	Neutral	0.195
BRCA1	P38398-1.2	L152N	Pathogenic	0.729
BRCA1	P38398-1.2	L152P	Pathogenic	0.759
BRCA1	P38398-1.2	L152Q	Pathogenic	0.558
BRCA1	P38398-1.2	L152R	Pathogenic	0.629
BRCA1	P38398-1.2	L152S	Pathogenic	0.759
BRCA1	P38398-1.2	L152T	Pathogenic	0.585
BRCA1	P38398-1.2	L152V	Neutral	0.347
BRCA1	P38398-1.2	L152W	Pathogenic	0.712
BRCA1	P38398-1.2	L152Y	Pathogenic	0.512
BRCA1	P38398-1.2	S153A	Neutral	0.026
BRCA1	P38398-1.2	S153C	Neutral	0.06
BRCA1	P38398-1.2	S153D	Neutral	0.047
BRCA1	P38398-1.2	S153E	Neutral	0.069
BRCA1	P38398-1.2	S153F	Neutral	0.211
BRCA1	P38398-1.2	S153G	Neutral	0.056
BRCA1	P38398-1.2	S153H	Neutral	0.117
BRCA1	P38398-1.2	S153I	Neutral	0.174
BRCA1	P38398-1.2	S153K	Neutral	0.116
BRCA1	P38398-1.2	S153L	Neutral	0.174
BRCA1	P38398-1.2	S153M	Neutral	0.129
BRCA1	P38398-1.2	S153N	Neutral	0.037
BRCA1	P38398-1.2	S153P	Neutral	0.065
BRCA1	P38398-1.2	S153Q	Neutral	0.077
BRCA1	P38398-1.2	S153R	Neutral	0.202
BRCA1	P38398-1.2	S153T	Neutral	0.035
BRCA1	P38398-1.2	S153V	Neutral	0.122
BRCA1	P38398-1.2	S153W	Neutral	0.416
BRCA1	P38398-1.2	S153Y	Neutral	0.237
BRCA1	P38398-1.2	V154A	Neutral	0.178
BRCA1	P38398-1.2	V154C	Neutral	0.172
BRCA1	P38398-1.2	V154D	Neutral	0.271
BRCA1	P38398-1.2	V154E	Neutral	0.172
BRCA1	P38398-1.2	V154F	Neutral	0.208
BRCA1	P38398-1.2	V154G	Neutral	0.495
BRCA1	P38398-1.2	V154H	Neutral	0.27
BRCA1	P38398-1.2	V154I	Neutral	0.046
BRCA1	P38398-1.2	V154K	Neutral	0.269
BRCA1	P38398-1.2	V154L	Neutral	0.091
BRCA1	P38398-1.2	V154M	Neutral	0.091
BRCA1	P38398-1.2	V154N	Neutral	0.25
BRCA1	P38398-1.2	V154P	Neutral	0.214
BRCA1	P38398-1.2	V154Q	Neutral	0.189
BRCA1	P38398-1.2	V154R	Neutral	0.414
BRCA1	P38398-1.2	V154S	Neutral	0.281
BRCA1	P38398-1.2	V154T	Neutral	0.109
BRCA1	P38398-1.2	V154W	Pathogenic	0.502
BRCA1	P38398-1.2	V154Y	Neutral	0.232
BRCA1	P38398-1.2	Q155A	Neutral	0.176
BRCA1	P38398-1.2	Q155C	Neutral	0.222
BRCA1	P38398-1.2	Q155D	Neutral	0.08
BRCA1	P38398-1.2	Q155E	Neutral	0.027
BRCA1	P38398-1.2	Q155F	Neutral	0.194
BRCA1	P38398-1.2	Q155G	Neutral	0.32
BRCA1	P38398-1.2	Q155H	Neutral	0.054
BRCA1	P38398-1.2	Q155I	Neutral	0.159
BRCA1	P38398-1.2	Q155K	Neutral	0.054
BRCA1	P38398-1.2	Q155L	Neutral	0.116
BRCA1	P38398-1.2	Q155M	Neutral	0.06
BRCA1	P38398-1.2	Q155N	Neutral	0.072
BRCA1	P38398-1.2	Q155P	Neutral	0.113
BRCA1	P38398-1.2	Q155R	Neutral	0.071
BRCA1	P38398-1.2	Q155S	Neutral	0.116
BRCA1	P38398-1.2	Q155T	Neutral	0.107
BRCA1	P38398-1.2	Q155V	Neutral	0.115
BRCA1	P38398-1.2	Q155W	Neutral	0.236
BRCA1	P38398-1.2	Q155Y	Neutral	0.119
BRCA1	P38398-1.2	L156A	Pathogenic	0.747
BRCA1	P38398-1.2	L156C	Pathogenic	0.663
BRCA1	P38398-1.2	L156D	Pathogenic	0.835
BRCA1	P38398-1.2	L156E	Pathogenic	0.703
BRCA1	P38398-1.2	L156F	Neutral	0.431
BRCA1	P38398-1.2	L156G	Pathogenic	0.93
BRCA1	P38398-1.2	L156H	Pathogenic	0.663
BRCA1	P38398-1.2	L156I	Neutral	0.223
BRCA1	P38398-1.2	L156K	Pathogenic	0.599
BRCA1	P38398-1.2	L156M	Neutral	0.222
BRCA1	P38398-1.2	L156N	Pathogenic	0.76
BRCA1	P38398-1.2	L156P	Pathogenic	0.787
BRCA1	P38398-1.2	L156Q	Pathogenic	0.597
BRCA1	P38398-1.2	L156R	Pathogenic	0.666
BRCA1	P38398-1.2	L156S	Pathogenic	0.787
BRCA1	P38398-1.2	L156T	Pathogenic	0.624
BRCA1	P38398-1.2	L156V	Neutral	0.384
BRCA1	P38398-1.2	L156W	Pathogenic	0.744
BRCA1	P38398-1.2	L156Y	Pathogenic	0.552
BRCA1	P38398-1.2	S157A	Neutral	0.141
BRCA1	P38398-1.2	S157C	Neutral	0.282
BRCA1	P38398-1.2	S157D	Neutral	0.235
BRCA1	P38398-1.2	S157E	Neutral	0.314
BRCA1	P38398-1.2	S157F	Pathogenic	0.623
BRCA1	P38398-1.2	S157G	Neutral	0.266
BRCA1	P38398-1.2	S157H	Neutral	0.448
BRCA1	P38398-1.2	S157I	Pathogenic	0.564
BRCA1	P38398-1.2	S157K	Neutral	0.448
BRCA1	P38398-1.2	S157L	Pathogenic	0.564
BRCA1	P38398-1.2	S157M	Neutral	0.476
BRCA1	P38398-1.2	S157N	Neutral	0.193
BRCA1	P38398-1.2	S157P	Neutral	0.301
BRCA1	P38398-1.2	S157Q	Neutral	0.34
BRCA1	P38398-1.2	S157R	Pathogenic	0.609
BRCA1	P38398-1.2	S157T	Neutral	0.183
BRCA1	P38398-1.2	S157V	Neutral	0.462
BRCA1	P38398-1.2	S157W	Pathogenic	0.814
BRCA1	P38398-1.2	S157Y	Pathogenic	0.657
BRCA1	P38398-1.2	N158A	Neutral	0.195
BRCA1	P38398-1.2	N158C	Neutral	0.184
BRCA1	P38398-1.2	N158D	Neutral	0.046
BRCA1	P38398-1.2	N158E	Neutral	0.077
BRCA1	P38398-1.2	N158F	Neutral	0.298
BRCA1	P38398-1.2	N158G	Neutral	0.152
BRCA1	P38398-1.2	N158H	Neutral	0.065
BRCA1	P38398-1.2	N158I	Neutral	0.249
BRCA1	P38398-1.2	N158K	Neutral	0.129
BRCA1	P38398-1.2	N158L	Neutral	0.249
BRCA1	P38398-1.2	N158M	Neutral	0.189
BRCA1	P38398-1.2	N158P	Neutral	0.126
BRCA1	P38398-1.2	N158Q	Neutral	0.085
BRCA1	P38398-1.2	N158R	Neutral	0.165
BRCA1	P38398-1.2	N158S	Neutral	0.067
BRCA1	P38398-1.2	N158T	Neutral	0.062
BRCA1	P38398-1.2	N158V	Neutral	0.18
BRCA1	P38398-1.2	N158W	Pathogenic	0.53
BRCA1	P38398-1.2	N158Y	Neutral	0.255
BRCA1	P38398-1.2	L159A	Pathogenic	0.604
BRCA1	P38398-1.2	L159C	Pathogenic	0.503
BRCA1	P38398-1.2	L159D	Pathogenic	0.723
BRCA1	P38398-1.2	L159E	Pathogenic	0.549
BRCA1	P38398-1.2	L159F	Neutral	0.281
BRCA1	P38398-1.2	L159G	Pathogenic	0.873
BRCA1	P38398-1.2	L159H	Pathogenic	0.503
BRCA1	P38398-1.2	L159I	Neutral	0.129
BRCA1	P38398-1.2	L159K	Neutral	0.435
BRCA1	P38398-1.2	L159M	Neutral	0.128
BRCA1	P38398-1.2	L159N	Pathogenic	0.62
BRCA1	P38398-1.2	L159P	Pathogenic	0.656
BRCA1	P38398-1.2	L159Q	Neutral	0.433
BRCA1	P38398-1.2	L159R	Pathogenic	0.507
BRCA1	P38398-1.2	L159S	Pathogenic	0.656
BRCA1	P38398-1.2	L159T	Neutral	0.461
BRCA1	P38398-1.2	L159V	Neutral	0.244
BRCA1	P38398-1.2	L159W	Pathogenic	0.599
BRCA1	P38398-1.2	L159Y	Neutral	0.388
BRCA1	P38398-1.2	G160A	Pathogenic	0.514
BRCA1	P38398-1.2	G160C	Pathogenic	0.826
BRCA1	P38398-1.2	G160D	Pathogenic	0.72
BRCA1	P38398-1.2	G160E	Pathogenic	0.847
BRCA1	P38398-1.2	G160F	Pathogenic	0.933
BRCA1	P38398-1.2	G160H	Pathogenic	0.872
BRCA1	P38398-1.2	G160I	Pathogenic	0.94
BRCA1	P38398-1.2	G160K	Pathogenic	0.907
BRCA1	P38398-1.2	G160L	Pathogenic	0.94
BRCA1	P38398-1.2	G160M	Pathogenic	0.917
BRCA1	P38398-1.2	G160N	Pathogenic	0.667
BRCA1	P38398-1.2	G160P	Pathogenic	0.784
BRCA1	P38398-1.2	G160Q	Pathogenic	0.862
BRCA1	P38398-1.2	G160R	Pathogenic	0.929
BRCA1	P38398-1.2	G160S	Pathogenic	0.549
BRCA1	P38398-1.2	G160T	Pathogenic	0.796
BRCA1	P38398-1.2	G160V	Pathogenic	0.878
BRCA1	P38398-1.2	G160W	Pathogenic	0.947
BRCA1	P38398-1.2	G160Y	Pathogenic	0.942
BRCA1	P38398-1.2	T161A	Neutral	0.184
BRCA1	P38398-1.2	T161C	Neutral	0.174
BRCA1	P38398-1.2	T161D	Neutral	0.158
BRCA1	P38398-1.2	T161E	Neutral	0.204
BRCA1	P38398-1.2	T161F	Neutral	0.394
BRCA1	P38398-1.2	T161G	Neutral	0.416
BRCA1	P38398-1.2	T161H	Neutral	0.314
BRCA1	P38398-1.2	T161I	Neutral	0.261
BRCA1	P38398-1.2	T161K	Neutral	0.312
BRCA1	P38398-1.2	T161L	Neutral	0.261
BRCA1	P38398-1.2	T161M	Neutral	0.263
BRCA1	P38398-1.2	T161N	Neutral	0.118
BRCA1	P38398-1.2	T161P	Neutral	0.162
BRCA1	P38398-1.2	T161Q	Neutral	0.224
BRCA1	P38398-1.2	T161R	Neutral	0.377
BRCA1	P38398-1.2	T161S	Neutral	0.12
BRCA1	P38398-1.2	T161V	Neutral	0.14
BRCA1	P38398-1.2	T161W	Pathogenic	0.545
BRCA1	P38398-1.2	T161Y	Neutral	0.43
BRCA1	P38398-1.2	V162A	Neutral	0.071
BRCA1	P38398-1.2	V162C	Neutral	0.068
BRCA1	P38398-1.2	V162D	Neutral	0.116
BRCA1	P38398-1.2	V162E	Neutral	0.068
BRCA1	P38398-1.2	V162F	Neutral	0.085
BRCA1	P38398-1.2	V162G	Neutral	0.257
BRCA1	P38398-1.2	V162H	Neutral	0.115
BRCA1	P38398-1.2	V162I	Neutral	0.017
BRCA1	P38398-1.2	V162K	Neutral	0.114
BRCA1	P38398-1.2	V162L	Neutral	0.034
BRCA1	P38398-1.2	V162M	Neutral	0.034
BRCA1	P38398-1.2	V162N	Neutral	0.105
BRCA1	P38398-1.2	V162P	Neutral	0.087
BRCA1	P38398-1.2	V162Q	Neutral	0.076
BRCA1	P38398-1.2	V162R	Neutral	0.199
BRCA1	P38398-1.2	V162S	Neutral	0.121
BRCA1	P38398-1.2	V162T	Neutral	0.041
BRCA1	P38398-1.2	V162W	Neutral	0.261
BRCA1	P38398-1.2	V162Y	Neutral	0.096
BRCA1	P38398-1.2	R163A	Neutral	0.398
BRCA1	P38398-1.2	R163C	Neutral	0.47
BRCA1	P38398-1.2	R163D	Neutral	0.363
BRCA1	P38398-1.2	R163E	Neutral	0.156
BRCA1	P38398-1.2	R163F	Neutral	0.227
BRCA1	P38398-1.2	R163G	Pathogenic	0.594
BRCA1	P38398-1.2	R163H	Neutral	0.129
BRCA1	P38398-1.2	R163I	Neutral	0.273
BRCA1	P38398-1.2	R163K	Neutral	0.048
BRCA1	P38398-1.2	R163L	Neutral	0.207
BRCA1	P38398-1.2	R163M	Neutral	0.155
BRCA1	P38398-1.2	R163N	Neutral	0.197
BRCA1	P38398-1.2	R163P	Neutral	0.362
BRCA1	P38398-1.2	R163Q	Neutral	0.102
BRCA1	P38398-1.2	R163S	Neutral	0.368
BRCA1	P38398-1.2	R163T	Neutral	0.271
BRCA1	P38398-1.2	R163V	Neutral	0.367
BRCA1	P38398-1.2	R163W	Neutral	0.234
BRCA1	P38398-1.2	R163Y	Neutral	0.154
BRCA1	P38398-1.2	T164A	Neutral	0.022
BRCA1	P38398-1.2	T164C	Neutral	0.02
BRCA1	P38398-1.2	T164D	Neutral	0.018
BRCA1	P38398-1.2	T164E	Neutral	0.024
BRCA1	P38398-1.2	T164F	Neutral	0.06
BRCA1	P38398-1.2	T164G	Neutral	0.065
BRCA1	P38398-1.2	T164H	Neutral	0.043
BRCA1	P38398-1.2	T164I	Neutral	0.033
BRCA1	P38398-1.2	T164K	Neutral	0.042
BRCA1	P38398-1.2	T164L	Neutral	0.033
BRCA1	P38398-1.2	T164M	Neutral	0.034
BRCA1	P38398-1.2	T164N	Neutral	0.013
BRCA1	P38398-1.2	T164P	Neutral	0.019
BRCA1	P38398-1.2	T164Q	Neutral	0.027
BRCA1	P38398-1.2	T164R	Neutral	0.056
BRCA1	P38398-1.2	T164S	Neutral	0.013
BRCA1	P38398-1.2	T164V	Neutral	0.016
BRCA1	P38398-1.2	T164W	Neutral	0.105
BRCA1	P38398-1.2	T164Y	Neutral	0.068
BRCA1	P38398-1.2	L165A	Neutral	0.086
BRCA1	P38398-1.2	L165C	Neutral	0.059
BRCA1	P38398-1.2	L165D	Neutral	0.138
BRCA1	P38398-1.2	L165E	Neutral	0.07
BRCA1	P38398-1.2	L165F	Neutral	0.023
BRCA1	P38398-1.2	L165G	Neutral	0.297
BRCA1	P38398-1.2	L165H	Neutral	0.059
BRCA1	P38398-1.2	L165I	Neutral	0.009
BRCA1	P38398-1.2	L165K	Neutral	0.045
BRCA1	P38398-1.2	L165M	Neutral	0.009
BRCA1	P38398-1.2	L165N	Neutral	0.091
BRCA1	P38398-1.2	L165P	Neutral	0.105
BRCA1	P38398-1.2	L165Q	Neutral	0.045
BRCA1	P38398-1.2	L165R	Neutral	0.059
BRCA1	P38398-1.2	L165S	Neutral	0.105
BRCA1	P38398-1.2	L165T	Neutral	0.05
BRCA1	P38398-1.2	L165V	Neutral	0.019
BRCA1	P38398-1.2	L165W	Neutral	0.084
BRCA1	P38398-1.2	L165Y	Neutral	0.038
BRCA1	P38398-1.2	R166A	Neutral	0.454
BRCA1	P38398-1.2	R166C	Pathogenic	0.527
BRCA1	P38398-1.2	R166D	Neutral	0.418
BRCA1	P38398-1.2	R166E	Neutral	0.188
BRCA1	P38398-1.2	R166F	Neutral	0.27
BRCA1	P38398-1.2	R166G	Pathogenic	0.647
BRCA1	P38398-1.2	R166H	Neutral	0.157
BRCA1	P38398-1.2	R166I	Neutral	0.321
BRCA1	P38398-1.2	R166K	Neutral	0.059
BRCA1	P38398-1.2	R166L	Neutral	0.247
BRCA1	P38398-1.2	R166M	Neutral	0.187
BRCA1	P38398-1.2	R166N	Neutral	0.236
BRCA1	P38398-1.2	R166P	Neutral	0.416
BRCA1	P38398-1.2	R166Q	Neutral	0.125
BRCA1	P38398-1.2	R166S	Neutral	0.423
BRCA1	P38398-1.2	R166T	Neutral	0.319
BRCA1	P38398-1.2	R166V	Neutral	0.421
BRCA1	P38398-1.2	R166W	Neutral	0.277
BRCA1	P38398-1.2	R166Y	Neutral	0.186
BRCA1	P38398-1.2	T167A	Neutral	0.111
BRCA1	P38398-1.2	T167C	Neutral	0.105
BRCA1	P38398-1.2	T167D	Neutral	0.094
BRCA1	P38398-1.2	T167E	Neutral	0.125
BRCA1	P38398-1.2	T167F	Neutral	0.265
BRCA1	P38398-1.2	T167G	Neutral	0.283
BRCA1	P38398-1.2	T167H	Neutral	0.202
BRCA1	P38398-1.2	T167I	Neutral	0.164
BRCA1	P38398-1.2	T167K	Neutral	0.201
BRCA1	P38398-1.2	T167L	Neutral	0.164
BRCA1	P38398-1.2	T167M	Neutral	0.165
BRCA1	P38398-1.2	T167N	Neutral	0.069
BRCA1	P38398-1.2	T167P	Neutral	0.097
BRCA1	P38398-1.2	T167Q	Neutral	0.138
BRCA1	P38398-1.2	T167R	Neutral	0.251
BRCA1	P38398-1.2	T167S	Neutral	0.071
BRCA1	P38398-1.2	T167V	Neutral	0.083
BRCA1	P38398-1.2	T167W	Neutral	0.399
BRCA1	P38398-1.2	T167Y	Neutral	0.295
BRCA1	P38398-1.2	K168A	Neutral	0.206
BRCA1	P38398-1.2	K168C	Neutral	0.258
BRCA1	P38398-1.2	K168D	Neutral	0.135
BRCA1	P38398-1.2	K168E	Neutral	0.048
BRCA1	P38398-1.2	K168F	Neutral	0.103
BRCA1	P38398-1.2	K168G	Neutral	0.364
BRCA1	P38398-1.2	K168H	Neutral	0.077
BRCA1	P38398-1.2	K168I	Neutral	0.128
BRCA1	P38398-1.2	K168L	Neutral	0.093
BRCA1	P38398-1.2	K168M	Neutral	0.067
BRCA1	P38398-1.2	K168N	Neutral	0.088
BRCA1	P38398-1.2	K168P	Neutral	0.134
BRCA1	P38398-1.2	K168Q	Neutral	0.043
BRCA1	P38398-1.2	K168R	Neutral	0.026
BRCA1	P38398-1.2	K168S	Neutral	0.137
BRCA1	P38398-1.2	K168T	Neutral	0.127
BRCA1	P38398-1.2	K168V	Neutral	0.136
BRCA1	P38398-1.2	K168W	Neutral	0.176
BRCA1	P38398-1.2	K168Y	Neutral	0.085
BRCA1	P38398-1.2	Q169A	Neutral	0.419
BRCA1	P38398-1.2	Q169C	Neutral	0.491
BRCA1	P38398-1.2	Q169D	Neutral	0.227
BRCA1	P38398-1.2	Q169E	Neutral	0.087
BRCA1	P38398-1.2	Q169F	Neutral	0.449
BRCA1	P38398-1.2	Q169G	Pathogenic	0.614
BRCA1	P38398-1.2	Q169H	Neutral	0.162
BRCA1	P38398-1.2	Q169I	Neutral	0.389
BRCA1	P38398-1.2	Q169K	Neutral	0.163
BRCA1	P38398-1.2	Q169L	Neutral	0.307
BRCA1	P38398-1.2	Q169M	Neutral	0.178
BRCA1	P38398-1.2	Q169N	Neutral	0.209
BRCA1	P38398-1.2	Q169P	Neutral	0.3
BRCA1	P38398-1.2	Q169R	Neutral	0.206
BRCA1	P38398-1.2	Q169S	Neutral	0.306
BRCA1	P38398-1.2	Q169T	Neutral	0.288
BRCA1	P38398-1.2	Q169V	Neutral	0.305
BRCA1	P38398-1.2	Q169W	Pathogenic	0.511
BRCA1	P38398-1.2	Q169Y	Neutral	0.313
BRCA1	P38398-1.2	R170A	Neutral	0.226
BRCA1	P38398-1.2	R170C	Neutral	0.281
BRCA1	P38398-1.2	R170D	Neutral	0.201
BRCA1	P38398-1.2	R170E	Neutral	0.075
BRCA1	P38398-1.2	R170F	Neutral	0.115
BRCA1	P38398-1.2	R170G	Neutral	0.392
BRCA1	P38398-1.2	R170H	Neutral	0.061
BRCA1	P38398-1.2	R170I	Neutral	0.142
BRCA1	P38398-1.2	R170K	Neutral	0.022
BRCA1	P38398-1.2	R170L	Neutral	0.103
BRCA1	P38398-1.2	R170M	Neutral	0.075
BRCA1	P38398-1.2	R170N	Neutral	0.098
BRCA1	P38398-1.2	R170P	Neutral	0.2
BRCA1	P38398-1.2	R170Q	Neutral	0.048
BRCA1	P38398-1.2	R170S	Neutral	0.204
BRCA1	P38398-1.2	R170T	Neutral	0.141
BRCA1	P38398-1.2	R170V	Neutral	0.203
BRCA1	P38398-1.2	R170W	Neutral	0.118
BRCA1	P38398-1.2	R170Y	Neutral	0.074
BRCA1	P38398-1.2	I171A	Neutral	0.026
BRCA1	P38398-1.2	I171C	Neutral	0.017
BRCA1	P38398-1.2	I171D	Neutral	0.03
BRCA1	P38398-1.2	I171E	Neutral	0.021
BRCA1	P38398-1.2	I171F	Neutral	0.007
BRCA1	P38398-1.2	I171G	Neutral	0.106
BRCA1	P38398-1.2	I171H	Neutral	0.017
BRCA1	P38398-1.2	I171K	Neutral	0.019
BRCA1	P38398-1.2	I171L	Neutral	0.003
BRCA1	P38398-1.2	I171M	Neutral	0.004
BRCA1	P38398-1.2	I171N	Neutral	0.027
BRCA1	P38398-1.2	I171P	Neutral	0.032
BRCA1	P38398-1.2	I171Q	Neutral	0.019
BRCA1	P38398-1.2	I171R	Neutral	0.025
BRCA1	P38398-1.2	I171S	Neutral	0.032
BRCA1	P38398-1.2	I171T	Neutral	0.015
BRCA1	P38398-1.2	I171V	Neutral	0.003
BRCA1	P38398-1.2	I171W	Neutral	0.036
BRCA1	P38398-1.2	I171Y	Neutral	0.011
BRCA1	P38398-1.2	Q172A	Pathogenic	0.605
BRCA1	P38398-1.2	Q172C	Pathogenic	0.673
BRCA1	P38398-1.2	Q172D	Neutral	0.385
BRCA1	P38398-1.2	Q172E	Neutral	0.169
BRCA1	P38398-1.2	Q172F	Pathogenic	0.634
BRCA1	P38398-1.2	Q172G	Pathogenic	0.772
BRCA1	P38398-1.2	Q172H	Neutral	0.291
BRCA1	P38398-1.2	Q172I	Pathogenic	0.576
BRCA1	P38398-1.2	Q172K	Neutral	0.293
BRCA1	P38398-1.2	Q172L	Neutral	0.486
BRCA1	P38398-1.2	Q172M	Neutral	0.315
BRCA1	P38398-1.2	Q172N	Neutral	0.359
BRCA1	P38398-1.2	Q172P	Neutral	0.477
BRCA1	P38398-1.2	Q172R	Neutral	0.356
BRCA1	P38398-1.2	Q172S	Neutral	0.484
BRCA1	P38398-1.2	Q172T	Neutral	0.463
BRCA1	P38398-1.2	Q172V	Neutral	0.483
BRCA1	P38398-1.2	Q172W	Pathogenic	0.69
BRCA1	P38398-1.2	Q172Y	Neutral	0.493
BRCA1	P38398-1.2	P173A	Neutral	0.201
BRCA1	P38398-1.2	P173C	Neutral	0.255
BRCA1	P38398-1.2	P173D	Neutral	0.131
BRCA1	P38398-1.2	P173E	Neutral	0.184
BRCA1	P38398-1.2	P173F	Pathogenic	0.546
BRCA1	P38398-1.2	P173G	Neutral	0.354
BRCA1	P38398-1.2	P173H	Neutral	0.287
BRCA1	P38398-1.2	P173I	Neutral	0.396
BRCA1	P38398-1.2	P173K	Neutral	0.285
BRCA1	P38398-1.2	P173L	Neutral	0.396
BRCA1	P38398-1.2	P173M	Neutral	0.315
BRCA1	P38398-1.2	P173N	Neutral	0.196
BRCA1	P38398-1.2	P173Q	Neutral	0.203
BRCA1	P38398-1.2	P173R	Neutral	0.434
BRCA1	P38398-1.2	P173S	Neutral	0.179
BRCA1	P38398-1.2	P173T	Neutral	0.139
BRCA1	P38398-1.2	P173V	Neutral	0.232
BRCA1	P38398-1.2	P173W	Pathogenic	0.69
BRCA1	P38398-1.2	P173Y	Neutral	0.493
BRCA1	P38398-1.2	Q174A	Neutral	0.159
BRCA1	P38398-1.2	Q174C	Neutral	0.203
BRCA1	P38398-1.2	Q174D	Neutral	0.072
BRCA1	P38398-1.2	Q174E	Neutral	0.024
BRCA1	P38398-1.2	Q174F	Neutral	0.176
BRCA1	P38398-1.2	Q174G	Neutral	0.295
BRCA1	P38398-1.2	Q174H	Neutral	0.048
BRCA1	P38398-1.2	Q174I	Neutral	0.144
BRCA1	P38398-1.2	Q174K	Neutral	0.049
BRCA1	P38398-1.2	Q174L	Neutral	0.104
BRCA1	P38398-1.2	Q174M	Neutral	0.054
BRCA1	P38398-1.2	Q174N	Neutral	0.065
BRCA1	P38398-1.2	Q174P	Neutral	0.101
BRCA1	P38398-1.2	Q174R	Neutral	0.064
BRCA1	P38398-1.2	Q174S	Neutral	0.104
BRCA1	P38398-1.2	Q174T	Neutral	0.096
BRCA1	P38398-1.2	Q174V	Neutral	0.103
BRCA1	P38398-1.2	Q174W	Neutral	0.215
BRCA1	P38398-1.2	Q174Y	Neutral	0.107
BRCA1	P38398-1.2	K175A	Neutral	0.187
BRCA1	P38398-1.2	K175C	Neutral	0.236
BRCA1	P38398-1.2	K175D	Neutral	0.121
BRCA1	P38398-1.2	K175E	Neutral	0.043
BRCA1	P38398-1.2	K175F	Neutral	0.093
BRCA1	P38398-1.2	K175G	Neutral	0.337
BRCA1	P38398-1.2	K175H	Neutral	0.069
BRCA1	P38398-1.2	K175I	Neutral	0.116
BRCA1	P38398-1.2	K175L	Neutral	0.083
BRCA1	P38398-1.2	K175M	Neutral	0.06
BRCA1	P38398-1.2	K175N	Neutral	0.079
BRCA1	P38398-1.2	K175P	Neutral	0.121
BRCA1	P38398-1.2	K175Q	Neutral	0.038
BRCA1	P38398-1.2	K175R	Neutral	0.023
BRCA1	P38398-1.2	K175S	Neutral	0.124
BRCA1	P38398-1.2	K175T	Neutral	0.115
BRCA1	P38398-1.2	K175V	Neutral	0.123
BRCA1	P38398-1.2	K175W	Neutral	0.159
BRCA1	P38398-1.2	K175Y	Neutral	0.076
BRCA1	P38398-1.2	T176A	Neutral	0.091
BRCA1	P38398-1.2	T176C	Neutral	0.086
BRCA1	P38398-1.2	T176D	Neutral	0.077
BRCA1	P38398-1.2	T176E	Neutral	0.102
BRCA1	P38398-1.2	T176F	Neutral	0.224
BRCA1	P38398-1.2	T176G	Neutral	0.24
BRCA1	P38398-1.2	T176H	Neutral	0.169
BRCA1	P38398-1.2	T176I	Neutral	0.136
BRCA1	P38398-1.2	T176K	Neutral	0.168
BRCA1	P38398-1.2	T176L	Neutral	0.136
BRCA1	P38398-1.2	T176M	Neutral	0.137
BRCA1	P38398-1.2	T176N	Neutral	0.056
BRCA1	P38398-1.2	T176P	Neutral	0.079
BRCA1	P38398-1.2	T176Q	Neutral	0.114
BRCA1	P38398-1.2	T176R	Neutral	0.212
BRCA1	P38398-1.2	T176S	Neutral	0.057
BRCA1	P38398-1.2	T176V	Neutral	0.067
BRCA1	P38398-1.2	T176W	Neutral	0.347
BRCA1	P38398-1.2	T176Y	Neutral	0.251
BRCA1	P38398-1.2	S177A	Neutral	0.06
BRCA1	P38398-1.2	S177C	Neutral	0.132
BRCA1	P38398-1.2	S177D	Neutral	0.106
BRCA1	P38398-1.2	S177E	Neutral	0.151
BRCA1	P38398-1.2	S177F	Neutral	0.39
BRCA1	P38398-1.2	S177G	Neutral	0.123
BRCA1	P38398-1.2	S177H	Neutral	0.24
BRCA1	P38398-1.2	S177I	Neutral	0.334
BRCA1	P38398-1.2	S177K	Neutral	0.239
BRCA1	P38398-1.2	S177L	Neutral	0.334
BRCA1	P38398-1.2	S177M	Neutral	0.261
BRCA1	P38398-1.2	S177N	Neutral	0.085
BRCA1	P38398-1.2	S177P	Neutral	0.143
BRCA1	P38398-1.2	S177Q	Neutral	0.167
BRCA1	P38398-1.2	S177R	Neutral	0.377
BRCA1	P38398-1.2	S177T	Neutral	0.08
BRCA1	P38398-1.2	S177V	Neutral	0.25
BRCA1	P38398-1.2	S177W	Pathogenic	0.63
BRCA1	P38398-1.2	S177Y	Neutral	0.426
BRCA1	P38398-1.2	V178A	Pathogenic	0.572
BRCA1	P38398-1.2	V178C	Pathogenic	0.561
BRCA1	P38398-1.2	V178D	Pathogenic	0.696
BRCA1	P38398-1.2	V178E	Pathogenic	0.561
BRCA1	P38398-1.2	V178F	Pathogenic	0.618
BRCA1	P38398-1.2	V178G	Pathogenic	0.858
BRCA1	P38398-1.2	V178H	Pathogenic	0.695
BRCA1	P38398-1.2	V178I	Neutral	0.228
BRCA1	P38398-1.2	V178K	Pathogenic	0.693
BRCA1	P38398-1.2	V178L	Neutral	0.38
BRCA1	P38398-1.2	V178M	Neutral	0.382
BRCA1	P38398-1.2	V178N	Pathogenic	0.672
BRCA1	P38398-1.2	V178P	Pathogenic	0.626
BRCA1	P38398-1.2	V178Q	Pathogenic	0.59
BRCA1	P38398-1.2	V178R	Pathogenic	0.813
BRCA1	P38398-1.2	V178S	Pathogenic	0.706
BRCA1	P38398-1.2	V178T	Neutral	0.428
BRCA1	P38398-1.2	V178W	Pathogenic	0.861
BRCA1	P38398-1.2	V178Y	Pathogenic	0.65
BRCA1	P38398-1.2	Y179A	Pathogenic	0.97
BRCA1	P38398-1.2	Y179C	Pathogenic	0.956
BRCA1	P38398-1.2	Y179D	Pathogenic	0.964
BRCA1	P38398-1.2	Y179E	Pathogenic	0.927
BRCA1	P38398-1.2	Y179F	Pathogenic	0.538
BRCA1	P38398-1.2	Y179G	Pathogenic	0.986
BRCA1	P38398-1.2	Y179H	Pathogenic	0.71
BRCA1	P38398-1.2	Y179I	Pathogenic	0.865
BRCA1	P38398-1.2	Y179K	Pathogenic	0.876
BRCA1	P38398-1.2	Y179L	Pathogenic	0.865
BRCA1	P38398-1.2	Y179M	Pathogenic	0.866
BRCA1	P38398-1.2	Y179N	Pathogenic	0.944
BRCA1	P38398-1.2	Y179P	Pathogenic	0.966
BRCA1	P38398-1.2	Y179Q	Pathogenic	0.888
BRCA1	P38398-1.2	Y179R	Pathogenic	0.878
BRCA1	P38398-1.2	Y179S	Pathogenic	0.966
BRCA1	P38398-1.2	Y179T	Pathogenic	0.948
BRCA1	P38398-1.2	Y179V	Pathogenic	0.908
BRCA1	P38398-1.2	Y179W	Pathogenic	0.704
BRCA1	P38398-1.2	I180A	Pathogenic	0.845
BRCA1	P38398-1.2	I180C	Pathogenic	0.784
BRCA1	P38398-1.2	I180D	Pathogenic	0.866
BRCA1	P38398-1.2	I180E	Pathogenic	0.814
BRCA1	P38398-1.2	I180F	Pathogenic	0.584
BRCA1	P38398-1.2	I180G	Pathogenic	0.961
BRCA1	P38398-1.2	I180H	Pathogenic	0.784
BRCA1	P38398-1.2	I180K	Pathogenic	0.799
BRCA1	P38398-1.2	I180L	Neutral	0.346
BRCA1	P38398-1.2	I180M	Neutral	0.43
BRCA1	P38398-1.2	I180N	Pathogenic	0.854
BRCA1	P38398-1.2	I180P	Pathogenic	0.872
BRCA1	P38398-1.2	I180Q	Pathogenic	0.797
BRCA1	P38398-1.2	I180R	Pathogenic	0.841
BRCA1	P38398-1.2	I180S	Pathogenic	0.872
BRCA1	P38398-1.2	I180T	Pathogenic	0.754
BRCA1	P38398-1.2	I180V	Neutral	0.357
BRCA1	P38398-1.2	I180W	Pathogenic	0.885
BRCA1	P38398-1.2	I180Y	Pathogenic	0.694
BRCA1	P38398-1.2	E181A	Neutral	0.17
BRCA1	P38398-1.2	E181C	Neutral	0.283
BRCA1	P38398-1.2	E181D	Neutral	0.039
BRCA1	P38398-1.2	E181F	Neutral	0.224
BRCA1	P38398-1.2	E181G	Neutral	0.311
BRCA1	P38398-1.2	E181H	Neutral	0.064
BRCA1	P38398-1.2	E181I	Neutral	0.184
BRCA1	P38398-1.2	E181K	Neutral	0.065
BRCA1	P38398-1.2	E181L	Neutral	0.185
BRCA1	P38398-1.2	E181M	Neutral	0.137
BRCA1	P38398-1.2	E181N	Neutral	0.071
BRCA1	P38398-1.2	E181P	Neutral	0.109
BRCA1	P38398-1.2	E181Q	Neutral	0.03
BRCA1	P38398-1.2	E181R	Neutral	0.119
BRCA1	P38398-1.2	E181S	Neutral	0.111
BRCA1	P38398-1.2	E181T	Neutral	0.103
BRCA1	P38398-1.2	E181V	Neutral	0.111
BRCA1	P38398-1.2	E181W	Neutral	0.348
BRCA1	P38398-1.2	E181Y	Neutral	0.189
BRCA1	P38398-1.2	L182A	Pathogenic	0.849
BRCA1	P38398-1.2	L182C	Pathogenic	0.789
BRCA1	P38398-1.2	L182D	Pathogenic	0.906
BRCA1	P38398-1.2	L182E	Pathogenic	0.819
BRCA1	P38398-1.2	L182F	Pathogenic	0.591
BRCA1	P38398-1.2	L182G	Pathogenic	0.962
BRCA1	P38398-1.2	L182H	Pathogenic	0.79
BRCA1	P38398-1.2	L182I	Neutral	0.354
BRCA1	P38398-1.2	L182K	Pathogenic	0.74
BRCA1	P38398-1.2	L182M	Neutral	0.352
BRCA1	P38398-1.2	L182N	Pathogenic	0.858
BRCA1	P38398-1.2	L182P	Pathogenic	0.876
BRCA1	P38398-1.2	L182Q	Pathogenic	0.739
BRCA1	P38398-1.2	L182R	Pathogenic	0.792
BRCA1	P38398-1.2	L182S	Pathogenic	0.876
BRCA1	P38398-1.2	L182T	Pathogenic	0.76
BRCA1	P38398-1.2	L182V	Pathogenic	0.544
BRCA1	P38398-1.2	L182W	Pathogenic	0.847
BRCA1	P38398-1.2	L182Y	Pathogenic	0.702
BRCA1	P38398-1.2	G183A	Neutral	0.353
BRCA1	P38398-1.2	G183C	Pathogenic	0.71
BRCA1	P38398-1.2	G183D	Pathogenic	0.57
BRCA1	P38398-1.2	G183E	Pathogenic	0.741
BRCA1	P38398-1.2	G183F	Pathogenic	0.877
BRCA1	P38398-1.2	G183H	Pathogenic	0.779
BRCA1	P38398-1.2	G183I	Pathogenic	0.89
BRCA1	P38398-1.2	G183K	Pathogenic	0.835
BRCA1	P38398-1.2	G183L	Pathogenic	0.89
BRCA1	P38398-1.2	G183M	Pathogenic	0.85
BRCA1	P38398-1.2	G183N	Pathogenic	0.508
BRCA1	P38398-1.2	G183P	Pathogenic	0.652
BRCA1	P38398-1.2	G183Q	Pathogenic	0.763
BRCA1	P38398-1.2	G183R	Pathogenic	0.871
BRCA1	P38398-1.2	G183S	Neutral	0.385
BRCA1	P38398-1.2	G183T	Pathogenic	0.669
BRCA1	P38398-1.2	G183V	Pathogenic	0.788
BRCA1	P38398-1.2	G183W	Pathogenic	0.902
BRCA1	P38398-1.2	G183Y	Pathogenic	0.893
BRCA1	P38398-1.2	S184A	Neutral	0.392
BRCA1	P38398-1.2	S184C	Pathogenic	0.606
BRCA1	P38398-1.2	S184D	Pathogenic	0.546
BRCA1	P38398-1.2	S184E	Pathogenic	0.643
BRCA1	P38398-1.2	S184F	Pathogenic	0.866
BRCA1	P38398-1.2	S184G	Pathogenic	0.587
BRCA1	P38398-1.2	S184H	Pathogenic	0.761
BRCA1	P38398-1.2	S184I	Pathogenic	0.835
BRCA1	P38398-1.2	S184K	Pathogenic	0.761
BRCA1	P38398-1.2	S184L	Pathogenic	0.836
BRCA1	P38398-1.2	S184M	Pathogenic	0.781
BRCA1	P38398-1.2	S184N	Neutral	0.484
BRCA1	P38398-1.2	S184P	Pathogenic	0.628
BRCA1	P38398-1.2	S184Q	Pathogenic	0.669
BRCA1	P38398-1.2	S184R	Pathogenic	0.859
BRCA1	P38398-1.2	S184T	Neutral	0.468
BRCA1	P38398-1.2	S184V	Pathogenic	0.771
BRCA1	P38398-1.2	S184W	Pathogenic	0.945
BRCA1	P38398-1.2	S184Y	Pathogenic	0.883
BRCA1	P38398-1.2	D185A	Pathogenic	0.833
BRCA1	P38398-1.2	D185C	Pathogenic	0.823
BRCA1	P38398-1.2	D185E	Pathogenic	0.508
BRCA1	P38398-1.2	D185F	Pathogenic	0.916
BRCA1	P38398-1.2	D185G	Pathogenic	0.841
BRCA1	P38398-1.2	D185H	Pathogenic	0.788
BRCA1	P38398-1.2	D185I	Pathogenic	0.895
BRCA1	P38398-1.2	D185K	Pathogenic	0.846
BRCA1	P38398-1.2	D185L	Pathogenic	0.925
BRCA1	P38398-1.2	D185M	Pathogenic	0.896
BRCA1	P38398-1.2	D185N	Pathogenic	0.527
BRCA1	P38398-1.2	D185P	Pathogenic	0.673
BRCA1	P38398-1.2	D185Q	Pathogenic	0.704
BRCA1	P38398-1.2	D185R	Pathogenic	0.913
BRCA1	P38398-1.2	D185S	Pathogenic	0.679
BRCA1	P38398-1.2	D185T	Pathogenic	0.68
BRCA1	P38398-1.2	D185V	Pathogenic	0.849
BRCA1	P38398-1.2	D185W	Pathogenic	0.966
BRCA1	P38398-1.2	D185Y	Pathogenic	0.926
BRCA1	P38398-1.2	S186A	Neutral	0.392
BRCA1	P38398-1.2	S186C	Pathogenic	0.606
BRCA1	P38398-1.2	S186D	Pathogenic	0.546
BRCA1	P38398-1.2	S186E	Pathogenic	0.643
BRCA1	P38398-1.2	S186F	Pathogenic	0.866
BRCA1	P38398-1.2	S186G	Pathogenic	0.587
BRCA1	P38398-1.2	S186H	Pathogenic	0.761
BRCA1	P38398-1.2	S186I	Pathogenic	0.835
BRCA1	P38398-1.2	S186K	Pathogenic	0.761
BRCA1	P38398-1.2	S186L	Pathogenic	0.836
BRCA1	P38398-1.2	S186M	Pathogenic	0.781
BRCA1	P38398-1.2	S186N	Neutral	0.484
BRCA1	P38398-1.2	S186P	Pathogenic	0.628
BRCA1	P38398-1.2	S186Q	Pathogenic	0.669
BRCA1	P38398-1.2	S186R	Pathogenic	0.859
BRCA1	P38398-1.2	S186T	Neutral	0.468
BRCA1	P38398-1.2	S186V	Pathogenic	0.771
BRCA1	P38398-1.2	S186W	Pathogenic	0.945
BRCA1	P38398-1.2	S186Y	Pathogenic	0.883
BRCA1	P38398-1.2	S187A	Neutral	0.392
BRCA1	P38398-1.2	S187C	Pathogenic	0.606
BRCA1	P38398-1.2	S187D	Pathogenic	0.546
BRCA1	P38398-1.2	S187E	Pathogenic	0.643
BRCA1	P38398-1.2	S187F	Pathogenic	0.866
BRCA1	P38398-1.2	S187G	Pathogenic	0.587
BRCA1	P38398-1.2	S187H	Pathogenic	0.761
BRCA1	P38398-1.2	S187I	Pathogenic	0.835
BRCA1	P38398-1.2	S187K	Pathogenic	0.761
BRCA1	P38398-1.2	S187L	Pathogenic	0.836
BRCA1	P38398-1.2	S187M	Pathogenic	0.781
BRCA1	P38398-1.2	S187N	Neutral	0.484
BRCA1	P38398-1.2	S187P	Pathogenic	0.628
BRCA1	P38398-1.2	S187Q	Pathogenic	0.669
BRCA1	P38398-1.2	S187R	Pathogenic	0.859
BRCA1	P38398-1.2	S187T	Neutral	0.468
BRCA1	P38398-1.2	S187V	Pathogenic	0.771
BRCA1	P38398-1.2	S187W	Pathogenic	0.945
BRCA1	P38398-1.2	S187Y	Pathogenic	0.883
BRCA1	P38398-1.2	E188A	Pathogenic	0.524
BRCA1	P38398-1.2	E188C	Pathogenic	0.679
BRCA1	P38398-1.2	E188D	Neutral	0.18
BRCA1	P38398-1.2	E188F	Pathogenic	0.608
BRCA1	P38398-1.2	E188G	Pathogenic	0.708
BRCA1	P38398-1.2	E188H	Neutral	0.269
BRCA1	P38398-1.2	E188I	Pathogenic	0.548
BRCA1	P38398-1.2	E188K	Neutral	0.273
BRCA1	P38398-1.2	E188L	Pathogenic	0.549
BRCA1	P38398-1.2	E188M	Neutral	0.46
BRCA1	P38398-1.2	E188N	Neutral	0.29
BRCA1	P38398-1.2	E188P	Neutral	0.395
BRCA1	P38398-1.2	E188Q	Neutral	0.141
BRCA1	P38398-1.2	E188R	Neutral	0.419
BRCA1	P38398-1.2	E188S	Neutral	0.402
BRCA1	P38398-1.2	E188T	Neutral	0.382
BRCA1	P38398-1.2	E188V	Neutral	0.401
BRCA1	P38398-1.2	E188W	Pathogenic	0.741
BRCA1	P38398-1.2	E188Y	Pathogenic	0.556
BRCA1	P38398-1.2	D189A	Pathogenic	0.529
BRCA1	P38398-1.2	D189C	Pathogenic	0.511
BRCA1	P38398-1.2	D189E	Neutral	0.189
BRCA1	P38398-1.2	D189F	Pathogenic	0.71
BRCA1	P38398-1.2	D189G	Pathogenic	0.545
BRCA1	P38398-1.2	D189H	Neutral	0.455
BRCA1	P38398-1.2	D189I	Pathogenic	0.657
BRCA1	P38398-1.2	D189K	Pathogenic	0.553
BRCA1	P38398-1.2	D189L	Pathogenic	0.734
BRCA1	P38398-1.2	D189M	Pathogenic	0.659
BRCA1	P38398-1.2	D189N	Neutral	0.201
BRCA1	P38398-1.2	D189P	Neutral	0.317
BRCA1	P38398-1.2	D189Q	Neutral	0.349
BRCA1	P38398-1.2	D189R	Pathogenic	0.703
BRCA1	P38398-1.2	D189S	Neutral	0.323
BRCA1	P38398-1.2	D189T	Neutral	0.324
BRCA1	P38398-1.2	D189V	Pathogenic	0.559
BRCA1	P38398-1.2	D189W	Pathogenic	0.867
BRCA1	P38398-1.2	D189Y	Pathogenic	0.74
BRCA1	P38398-1.2	T190A	Neutral	0.05
BRCA1	P38398-1.2	T190C	Neutral	0.047
BRCA1	P38398-1.2	T190D	Neutral	0.042
BRCA1	P38398-1.2	T190E	Neutral	0.056
BRCA1	P38398-1.2	T190F	Neutral	0.131
BRCA1	P38398-1.2	T190G	Neutral	0.142
BRCA1	P38398-1.2	T190H	Neutral	0.096
BRCA1	P38398-1.2	T190I	Neutral	0.076
BRCA1	P38398-1.2	T190K	Neutral	0.096
BRCA1	P38398-1.2	T190L	Neutral	0.076
BRCA1	P38398-1.2	T190M	Neutral	0.077
BRCA1	P38398-1.2	T190N	Neutral	0.03
BRCA1	P38398-1.2	T190P	Neutral	0.043
BRCA1	P38398-1.2	T190Q	Neutral	0.063
BRCA1	P38398-1.2	T190R	Neutral	0.124
BRCA1	P38398-1.2	T190S	Neutral	0.031
BRCA1	P38398-1.2	T190V	Neutral	0.037
BRCA1	P38398-1.2	T190W	Neutral	0.218
BRCA1	P38398-1.2	T190Y	Neutral	0.149
BRCA1	P38398-1.2	V191A	Neutral	0.243
BRCA1	P38398-1.2	V191C	Neutral	0.235
BRCA1	P38398-1.2	V191D	Neutral	0.355
BRCA1	P38398-1.2	V191E	Neutral	0.235
BRCA1	P38398-1.2	V191F	Neutral	0.28
BRCA1	P38398-1.2	V191G	Pathogenic	0.592
BRCA1	P38398-1.2	V191H	Neutral	0.354
BRCA1	P38398-1.2	V191I	Neutral	0.066
BRCA1	P38398-1.2	V191K	Neutral	0.352
BRCA1	P38398-1.2	V191L	Neutral	0.129
BRCA1	P38398-1.2	V191M	Neutral	0.13
BRCA1	P38398-1.2	V191N	Neutral	0.331
BRCA1	P38398-1.2	V191P	Neutral	0.287
BRCA1	P38398-1.2	V191Q	Neutral	0.257
BRCA1	P38398-1.2	V191R	Pathogenic	0.51
BRCA1	P38398-1.2	V191S	Neutral	0.366
BRCA1	P38398-1.2	V191T	Neutral	0.153
BRCA1	P38398-1.2	V191W	Pathogenic	0.598
BRCA1	P38398-1.2	V191Y	Neutral	0.309
BRCA1	P38398-1.2	N192A	Neutral	0.223
BRCA1	P38398-1.2	N192C	Neutral	0.211
BRCA1	P38398-1.2	N192D	Neutral	0.054
BRCA1	P38398-1.2	N192E	Neutral	0.09
BRCA1	P38398-1.2	N192F	Neutral	0.334
BRCA1	P38398-1.2	N192G	Neutral	0.175
BRCA1	P38398-1.2	N192H	Neutral	0.076
BRCA1	P38398-1.2	N192I	Neutral	0.282
BRCA1	P38398-1.2	N192K	Neutral	0.149
BRCA1	P38398-1.2	N192L	Neutral	0.282
BRCA1	P38398-1.2	N192M	Neutral	0.216
BRCA1	P38398-1.2	N192P	Neutral	0.146
BRCA1	P38398-1.2	N192Q	Neutral	0.099
BRCA1	P38398-1.2	N192R	Neutral	0.189
BRCA1	P38398-1.2	N192S	Neutral	0.078
BRCA1	P38398-1.2	N192T	Neutral	0.072
BRCA1	P38398-1.2	N192V	Neutral	0.206
BRCA1	P38398-1.2	N192W	Pathogenic	0.571
BRCA1	P38398-1.2	N192Y	Neutral	0.288
BRCA1	P38398-1.2	K193A	Neutral	0.159
BRCA1	P38398-1.2	K193C	Neutral	0.202
BRCA1	P38398-1.2	K193D	Neutral	0.102
BRCA1	P38398-1.2	K193E	Neutral	0.035
BRCA1	P38398-1.2	K193F	Neutral	0.078
BRCA1	P38398-1.2	K193G	Neutral	0.295
BRCA1	P38398-1.2	K193H	Neutral	0.058
BRCA1	P38398-1.2	K193I	Neutral	0.097
BRCA1	P38398-1.2	K193L	Neutral	0.07
BRCA1	P38398-1.2	K193M	Neutral	0.05
BRCA1	P38398-1.2	K193N	Neutral	0.066
BRCA1	P38398-1.2	K193P	Neutral	0.101
BRCA1	P38398-1.2	K193Q	Neutral	0.031
BRCA1	P38398-1.2	K193R	Neutral	0.019
BRCA1	P38398-1.2	K193S	Neutral	0.104
BRCA1	P38398-1.2	K193T	Neutral	0.096
BRCA1	P38398-1.2	K193V	Neutral	0.103
BRCA1	P38398-1.2	K193W	Neutral	0.134
BRCA1	P38398-1.2	K193Y	Neutral	0.064
BRCA1	P38398-1.2	A194C	Neutral	0.013
BRCA1	P38398-1.2	A194D	Neutral	0.029
BRCA1	P38398-1.2	A194E	Neutral	0.03
BRCA1	P38398-1.2	A194F	Neutral	0.072
BRCA1	P38398-1.2	A194G	Neutral	0.013
BRCA1	P38398-1.2	A194H	Neutral	0.052
BRCA1	P38398-1.2	A194I	Neutral	0.041
BRCA1	P38398-1.2	A194K	Neutral	0.051
BRCA1	P38398-1.2	A194L	Neutral	0.041
BRCA1	P38398-1.2	A194M	Neutral	0.041
BRCA1	P38398-1.2	A194N	Neutral	0.032
BRCA1	P38398-1.2	A194P	Neutral	0.02
BRCA1	P38398-1.2	A194Q	Neutral	0.033
BRCA1	P38398-1.2	A194R	Neutral	0.067
BRCA1	P38398-1.2	A194S	Neutral	0.007
BRCA1	P38398-1.2	A194T	Neutral	0.015
BRCA1	P38398-1.2	A194V	Neutral	0.019
BRCA1	P38398-1.2	A194W	Neutral	0.171
BRCA1	P38398-1.2	A194Y	Neutral	0.083
BRCA1	P38398-1.2	T195A	Neutral	0.001
BRCA1	P38398-1.2	T195C	Neutral	0.001
BRCA1	P38398-1.2	T195D	Neutral	0.001
BRCA1	P38398-1.2	T195E	Neutral	0.001
BRCA1	P38398-1.2	T195F	Neutral	0.003
BRCA1	P38398-1.2	T195G	Neutral	0.003
BRCA1	P38398-1.2	T195H	Neutral	0.002
BRCA1	P38398-1.2	T195I	Neutral	0.002
BRCA1	P38398-1.2	T195K	Neutral	0.002
BRCA1	P38398-1.2	T195L	Neutral	0.002
BRCA1	P38398-1.2	T195M	Neutral	0.002
BRCA1	P38398-1.2	T195N	Neutral	0.001
BRCA1	P38398-1.2	T195P	Neutral	0.001
BRCA1	P38398-1.2	T195Q	Neutral	0.001
BRCA1	P38398-1.2	T195R	Neutral	0.003
BRCA1	P38398-1.2	T195S	Neutral	0.001
BRCA1	P38398-1.2	T195V	Neutral	0.001
BRCA1	P38398-1.2	T195W	Neutral	0.005
BRCA1	P38398-1.2	T195Y	Neutral	0.003
BRCA1	P38398-1.2	Y196A	Neutral	0.21
BRCA1	P38398-1.2	Y196C	Neutral	0.15
BRCA1	P38398-1.2	Y196D	Neutral	0.18
BRCA1	P38398-1.2	Y196E	Neutral	0.093
BRCA1	P38398-1.2	Y196F	Neutral	0.009
BRCA1	P38398-1.2	Y196G	Neutral	0.367
BRCA1	P38398-1.2	Y196H	Neutral	0.019
BRCA1	P38398-1.2	Y196I	Neutral	0.049
BRCA1	P38398-1.2	Y196K	Neutral	0.054
BRCA1	P38398-1.2	Y196L	Neutral	0.049
BRCA1	P38398-1.2	Y196M	Neutral	0.05
BRCA1	P38398-1.2	Y196N	Neutral	0.12
BRCA1	P38398-1.2	Y196P	Neutral	0.188
BRCA1	P38398-1.2	Y196Q	Neutral	0.06
BRCA1	P38398-1.2	Y196R	Neutral	0.055
BRCA1	P38398-1.2	Y196S	Neutral	0.188
BRCA1	P38398-1.2	Y196T	Neutral	0.13
BRCA1	P38398-1.2	Y196V	Neutral	0.074
BRCA1	P38398-1.2	Y196W	Neutral	0.019
BRCA1	P38398-1.2	C197A	Neutral	0.023
BRCA1	P38398-1.2	C197D	Neutral	0.047
BRCA1	P38398-1.2	C197E	Neutral	0.097
BRCA1	P38398-1.2	C197F	Neutral	0.086
BRCA1	P38398-1.2	C197G	Neutral	0.095
BRCA1	P38398-1.2	C197H	Neutral	0.084
BRCA1	P38398-1.2	C197I	Neutral	0.048
BRCA1	P38398-1.2	C197K	Neutral	0.116
BRCA1	P38398-1.2	C197L	Neutral	0.049
BRCA1	P38398-1.2	C197M	Neutral	0.049
BRCA1	P38398-1.2	C197N	Neutral	0.053
BRCA1	P38398-1.2	C197P	Neutral	0.048
BRCA1	P38398-1.2	C197Q	Neutral	0.077
BRCA1	P38398-1.2	C197R	Neutral	0.149
BRCA1	P38398-1.2	C197S	Neutral	0.028
BRCA1	P38398-1.2	C197T	Neutral	0.025
BRCA1	P38398-1.2	C197V	Neutral	0.033
BRCA1	P38398-1.2	C197W	Neutral	0.147
BRCA1	P38398-1.2	C197Y	Neutral	0.098
BRCA1	P38398-1.2	S198A	Neutral	0.257
BRCA1	P38398-1.2	S198C	Neutral	0.453
BRCA1	P38398-1.2	S198D	Neutral	0.392
BRCA1	P38398-1.2	S198E	Neutral	0.491
BRCA1	P38398-1.2	S198F	Pathogenic	0.777
BRCA1	P38398-1.2	S198G	Neutral	0.433
BRCA1	P38398-1.2	S198H	Pathogenic	0.631
BRCA1	P38398-1.2	S198I	Pathogenic	0.731
BRCA1	P38398-1.2	S198K	Pathogenic	0.631
BRCA1	P38398-1.2	S198L	Pathogenic	0.732
BRCA1	P38398-1.2	S198M	Pathogenic	0.657
BRCA1	P38398-1.2	S198N	Neutral	0.335
BRCA1	P38398-1.2	S198P	Neutral	0.476
BRCA1	P38398-1.2	S198Q	Pathogenic	0.521
BRCA1	P38398-1.2	S198R	Pathogenic	0.766
BRCA1	P38398-1.2	S198T	Neutral	0.321
BRCA1	P38398-1.2	S198V	Pathogenic	0.644
BRCA1	P38398-1.2	S198W	Pathogenic	0.902
BRCA1	P38398-1.2	S198Y	Pathogenic	0.801
BRCA1	P38398-1.2	V199A	Neutral	0.222
BRCA1	P38398-1.2	V199C	Neutral	0.214
BRCA1	P38398-1.2	V199D	Neutral	0.328
BRCA1	P38398-1.2	V199E	Neutral	0.214
BRCA1	P38398-1.2	V199F	Neutral	0.257
BRCA1	P38398-1.2	V199G	Pathogenic	0.563
BRCA1	P38398-1.2	V199H	Neutral	0.327
BRCA1	P38398-1.2	V199I	Neutral	0.059
BRCA1	P38398-1.2	V199K	Neutral	0.325
BRCA1	P38398-1.2	V199L	Neutral	0.116
BRCA1	P38398-1.2	V199M	Neutral	0.117
BRCA1	P38398-1.2	V199N	Neutral	0.305
BRCA1	P38398-1.2	V199P	Neutral	0.263
BRCA1	P38398-1.2	V199Q	Neutral	0.235
BRCA1	P38398-1.2	V199R	Neutral	0.48
BRCA1	P38398-1.2	V199S	Neutral	0.339
BRCA1	P38398-1.2	V199T	Neutral	0.138
BRCA1	P38398-1.2	V199W	Pathogenic	0.569
BRCA1	P38398-1.2	V199Y	Neutral	0.284
BRCA1	P38398-1.2	G200A	Neutral	0.038
BRCA1	P38398-1.2	G200C	Neutral	0.149
BRCA1	P38398-1.2	G200D	Neutral	0.087
BRCA1	P38398-1.2	G200E	Neutral	0.17
BRCA1	P38398-1.2	G200F	Neutral	0.339
BRCA1	P38398-1.2	G200H	Neutral	0.201
BRCA1	P38398-1.2	G200I	Neutral	0.366
BRCA1	P38398-1.2	G200K	Neutral	0.266
BRCA1	P38398-1.2	G200L	Neutral	0.366
BRCA1	P38398-1.2	G200M	Neutral	0.289
BRCA1	P38398-1.2	G200N	Neutral	0.069
BRCA1	P38398-1.2	G200P	Neutral	0.118
BRCA1	P38398-1.2	G200Q	Neutral	0.187
BRCA1	P38398-1.2	G200R	Neutral	0.325
BRCA1	P38398-1.2	G200S	Neutral	0.043
BRCA1	P38398-1.2	G200T	Neutral	0.126
BRCA1	P38398-1.2	G200V	Neutral	0.21
BRCA1	P38398-1.2	G200W	Neutral	0.397
BRCA1	P38398-1.2	G200Y	Neutral	0.373
BRCA1	P38398-1.2	D201A	Pathogenic	0.551
BRCA1	P38398-1.2	D201C	Pathogenic	0.533
BRCA1	P38398-1.2	D201E	Neutral	0.203
BRCA1	P38398-1.2	D201F	Pathogenic	0.728
BRCA1	P38398-1.2	D201G	Pathogenic	0.567
BRCA1	P38398-1.2	D201H	Neutral	0.478
BRCA1	P38398-1.2	D201I	Pathogenic	0.677
BRCA1	P38398-1.2	D201K	Pathogenic	0.575
BRCA1	P38398-1.2	D201L	Pathogenic	0.751
BRCA1	P38398-1.2	D201M	Pathogenic	0.679
BRCA1	P38398-1.2	D201N	Neutral	0.215
BRCA1	P38398-1.2	D201P	Neutral	0.337
BRCA1	P38398-1.2	D201Q	Neutral	0.369
BRCA1	P38398-1.2	D201R	Pathogenic	0.722
BRCA1	P38398-1.2	D201S	Neutral	0.343
BRCA1	P38398-1.2	D201T	Neutral	0.344
BRCA1	P38398-1.2	D201V	Pathogenic	0.581
BRCA1	P38398-1.2	D201W	Pathogenic	0.877
BRCA1	P38398-1.2	D201Y	Pathogenic	0.756
BRCA1	P38398-1.2	Q202A	Neutral	0.032
BRCA1	P38398-1.2	Q202C	Neutral	0.043
BRCA1	P38398-1.2	Q202D	Neutral	0.013
BRCA1	P38398-1.2	Q202E	Neutral	0.004
BRCA1	P38398-1.2	Q202F	Neutral	0.036
BRCA1	P38398-1.2	Q202G	Neutral	0.068
BRCA1	P38398-1.2	Q202H	Neutral	0.009
BRCA1	P38398-1.2	Q202I	Neutral	0.029
BRCA1	P38398-1.2	Q202K	Neutral	0.009
BRCA1	P38398-1.2	Q202L	Neutral	0.02
BRCA1	P38398-1.2	Q202M	Neutral	0.01
BRCA1	P38398-1.2	Q202N	Neutral	0.012
BRCA1	P38398-1.2	Q202P	Neutral	0.019
BRCA1	P38398-1.2	Q202R	Neutral	0.012
BRCA1	P38398-1.2	Q202S	Neutral	0.02
BRCA1	P38398-1.2	Q202T	Neutral	0.018
BRCA1	P38398-1.2	Q202V	Neutral	0.02
BRCA1	P38398-1.2	Q202W	Neutral	0.046
BRCA1	P38398-1.2	Q202Y	Neutral	0.021
BRCA1	P38398-1.2	E203A	Neutral	0.13
BRCA1	P38398-1.2	E203C	Neutral	0.223
BRCA1	P38398-1.2	E203D	Neutral	0.029
BRCA1	P38398-1.2	E203F	Neutral	0.174
BRCA1	P38398-1.2	E203G	Neutral	0.248
BRCA1	P38398-1.2	E203H	Neutral	0.048
BRCA1	P38398-1.2	E203I	Neutral	0.141
BRCA1	P38398-1.2	E203K	Neutral	0.049
BRCA1	P38398-1.2	E203L	Neutral	0.142
BRCA1	P38398-1.2	E203M	Neutral	0.104
BRCA1	P38398-1.2	E203N	Neutral	0.052
BRCA1	P38398-1.2	E203P	Neutral	0.082
BRCA1	P38398-1.2	E203Q	Neutral	0.022
BRCA1	P38398-1.2	E203R	Neutral	0.089
BRCA1	P38398-1.2	E203S	Neutral	0.084
BRCA1	P38398-1.2	E203T	Neutral	0.077
BRCA1	P38398-1.2	E203V	Neutral	0.083
BRCA1	P38398-1.2	E203W	Neutral	0.28
BRCA1	P38398-1.2	E203Y	Neutral	0.145
BRCA1	P38398-1.2	L204A	Neutral	0.286
BRCA1	P38398-1.2	L204C	Neutral	0.21
BRCA1	P38398-1.2	L204D	Neutral	0.407
BRCA1	P38398-1.2	L204E	Neutral	0.243
BRCA1	P38398-1.2	L204F	Neutral	0.093
BRCA1	P38398-1.2	L204G	Pathogenic	0.645
BRCA1	P38398-1.2	L204H	Neutral	0.211
BRCA1	P38398-1.2	L204I	Neutral	0.037
BRCA1	P38398-1.2	L204K	Neutral	0.169
BRCA1	P38398-1.2	L204M	Neutral	0.037
BRCA1	P38398-1.2	L204N	Neutral	0.3
BRCA1	P38398-1.2	L204P	Neutral	0.334
BRCA1	P38398-1.2	L204Q	Neutral	0.168
BRCA1	P38398-1.2	L204R	Neutral	0.213
BRCA1	P38398-1.2	L204S	Neutral	0.334
BRCA1	P38398-1.2	L204T	Neutral	0.184
BRCA1	P38398-1.2	L204V	Neutral	0.078
BRCA1	P38398-1.2	L204W	Neutral	0.282
BRCA1	P38398-1.2	L204Y	Neutral	0.143
BRCA1	P38398-1.2	L205A	Neutral	0.334
BRCA1	P38398-1.2	L205C	Neutral	0.25
BRCA1	P38398-1.2	L205D	Neutral	0.463
BRCA1	P38398-1.2	L205E	Neutral	0.287
BRCA1	P38398-1.2	L205F	Neutral	0.114
BRCA1	P38398-1.2	L205G	Pathogenic	0.694
BRCA1	P38398-1.2	L205H	Neutral	0.25
BRCA1	P38398-1.2	L205I	Neutral	0.046
BRCA1	P38398-1.2	L205K	Neutral	0.202
BRCA1	P38398-1.2	L205M	Neutral	0.046
BRCA1	P38398-1.2	L205N	Neutral	0.349
BRCA1	P38398-1.2	L205P	Neutral	0.386
BRCA1	P38398-1.2	L205Q	Neutral	0.201
BRCA1	P38398-1.2	L205R	Neutral	0.253
BRCA1	P38398-1.2	L205S	Neutral	0.386
BRCA1	P38398-1.2	L205T	Neutral	0.22
BRCA1	P38398-1.2	L205V	Neutral	0.096
BRCA1	P38398-1.2	L205W	Neutral	0.33
BRCA1	P38398-1.2	L205Y	Neutral	0.173
BRCA1	P38398-1.2	Q206A	Neutral	0.089
BRCA1	P38398-1.2	Q206C	Neutral	0.116
BRCA1	P38398-1.2	Q206D	Neutral	0.038
BRCA1	P38398-1.2	Q206E	Neutral	0.013
BRCA1	P38398-1.2	Q206F	Neutral	0.1
BRCA1	P38398-1.2	Q206G	Neutral	0.178
BRCA1	P38398-1.2	Q206H	Neutral	0.026
BRCA1	P38398-1.2	Q206I	Neutral	0.08
BRCA1	P38398-1.2	Q206K	Neutral	0.026
BRCA1	P38398-1.2	Q206L	Neutral	0.057
BRCA1	P38398-1.2	Q206M	Neutral	0.029
BRCA1	P38398-1.2	Q206N	Neutral	0.035
BRCA1	P38398-1.2	Q206P	Neutral	0.055
BRCA1	P38398-1.2	Q206R	Neutral	0.034
BRCA1	P38398-1.2	Q206S	Neutral	0.057
BRCA1	P38398-1.2	Q206T	Neutral	0.052
BRCA1	P38398-1.2	Q206V	Neutral	0.056
BRCA1	P38398-1.2	Q206W	Neutral	0.124
BRCA1	P38398-1.2	Q206Y	Neutral	0.058
BRCA1	P38398-1.2	I207A	Neutral	0.049
BRCA1	P38398-1.2	I207C	Neutral	0.033
BRCA1	P38398-1.2	I207D	Neutral	0.058
BRCA1	P38398-1.2	I207E	Neutral	0.04
BRCA1	P38398-1.2	I207F	Neutral	0.013
BRCA1	P38398-1.2	I207G	Neutral	0.189
BRCA1	P38398-1.2	I207H	Neutral	0.033
BRCA1	P38398-1.2	I207K	Neutral	0.036
BRCA1	P38398-1.2	I207L	Neutral	0.005
BRCA1	P38398-1.2	I207M	Neutral	0.007
BRCA1	P38398-1.2	I207N	Neutral	0.052
BRCA1	P38398-1.2	I207P	Neutral	0.061
BRCA1	P38398-1.2	I207Q	Neutral	0.036
BRCA1	P38398-1.2	I207R	Neutral	0.048
BRCA1	P38398-1.2	I207S	Neutral	0.061
BRCA1	P38398-1.2	I207T	Neutral	0.028
BRCA1	P38398-1.2	I207V	Neutral	0.005
BRCA1	P38398-1.2	I207W	Neutral	0.068
BRCA1	P38398-1.2	I207Y	Neutral	0.021
BRCA1	P38398-1.2	T208A	Neutral	0.094
BRCA1	P38398-1.2	T208C	Neutral	0.088
BRCA1	P38398-1.2	T208D	Neutral	0.079
BRCA1	P38398-1.2	T208E	Neutral	0.106
BRCA1	P38398-1.2	T208F	Neutral	0.23
BRCA1	P38398-1.2	T208G	Neutral	0.247
BRCA1	P38398-1.2	T208H	Neutral	0.174
BRCA1	P38398-1.2	T208I	Neutral	0.14
BRCA1	P38398-1.2	T208K	Neutral	0.173
BRCA1	P38398-1.2	T208L	Neutral	0.14
BRCA1	P38398-1.2	T208M	Neutral	0.141
BRCA1	P38398-1.2	T208N	Neutral	0.058
BRCA1	P38398-1.2	T208P	Neutral	0.082
BRCA1	P38398-1.2	T208Q	Neutral	0.117
BRCA1	P38398-1.2	T208R	Neutral	0.218
BRCA1	P38398-1.2	T208S	Neutral	0.059
BRCA1	P38398-1.2	T208V	Neutral	0.07
BRCA1	P38398-1.2	T208W	Neutral	0.356
BRCA1	P38398-1.2	T208Y	Neutral	0.258
BRCA1	P38398-1.2	P209A	Neutral	0.248
BRCA1	P38398-1.2	P209C	Neutral	0.31
BRCA1	P38398-1.2	P209D	Neutral	0.165
BRCA1	P38398-1.2	P209E	Neutral	0.228
BRCA1	P38398-1.2	P209F	Pathogenic	0.613
BRCA1	P38398-1.2	P209G	Neutral	0.418
BRCA1	P38398-1.2	P209H	Neutral	0.346
BRCA1	P38398-1.2	P209I	Neutral	0.462
BRCA1	P38398-1.2	P209K	Neutral	0.344
BRCA1	P38398-1.2	P209L	Neutral	0.463
BRCA1	P38398-1.2	P209M	Neutral	0.377
BRCA1	P38398-1.2	P209N	Neutral	0.242
BRCA1	P38398-1.2	P209Q	Neutral	0.25
BRCA1	P38398-1.2	P209R	Pathogenic	0.502
BRCA1	P38398-1.2	P209S	Neutral	0.223
BRCA1	P38398-1.2	P209T	Neutral	0.174
BRCA1	P38398-1.2	P209V	Neutral	0.284
BRCA1	P38398-1.2	P209W	Pathogenic	0.745
BRCA1	P38398-1.2	P209Y	Pathogenic	0.561
BRCA1	P38398-1.2	Q210A	Neutral	0.234
BRCA1	P38398-1.2	Q210C	Neutral	0.29
BRCA1	P38398-1.2	Q210D	Neutral	0.11
BRCA1	P38398-1.2	Q210E	Neutral	0.039
BRCA1	P38398-1.2	Q210F	Neutral	0.256
BRCA1	P38398-1.2	Q210G	Neutral	0.402
BRCA1	P38398-1.2	Q210H	Neutral	0.076
BRCA1	P38398-1.2	Q210I	Neutral	0.212
BRCA1	P38398-1.2	Q210K	Neutral	0.076
BRCA1	P38398-1.2	Q210L	Neutral	0.158
BRCA1	P38398-1.2	Q210M	Neutral	0.084
BRCA1	P38398-1.2	Q210N	Neutral	0.1
BRCA1	P38398-1.2	Q210P	Neutral	0.154
BRCA1	P38398-1.2	Q210R	Neutral	0.099
BRCA1	P38398-1.2	Q210S	Neutral	0.157
BRCA1	P38398-1.2	Q210T	Neutral	0.146
BRCA1	P38398-1.2	Q210V	Neutral	0.156
BRCA1	P38398-1.2	Q210W	Neutral	0.306
BRCA1	P38398-1.2	Q210Y	Neutral	0.162
BRCA1	P38398-1.2	G211A	Neutral	0.177
BRCA1	P38398-1.2	G211C	Neutral	0.491
BRCA1	P38398-1.2	G211D	Neutral	0.343
BRCA1	P38398-1.2	G211E	Pathogenic	0.529
BRCA1	P38398-1.2	G211F	Pathogenic	0.738
BRCA1	P38398-1.2	G211H	Pathogenic	0.581
BRCA1	P38398-1.2	G211I	Pathogenic	0.761
BRCA1	P38398-1.2	G211K	Pathogenic	0.666
BRCA1	P38398-1.2	G211L	Pathogenic	0.761
BRCA1	P38398-1.2	G211M	Pathogenic	0.691
BRCA1	P38398-1.2	G211N	Neutral	0.289
BRCA1	P38398-1.2	G211P	Neutral	0.424
BRCA1	P38398-1.2	G211Q	Pathogenic	0.559
BRCA1	P38398-1.2	G211R	Pathogenic	0.726
BRCA1	P38398-1.2	G211S	Neutral	0.198
BRCA1	P38398-1.2	G211T	Neutral	0.443
BRCA1	P38398-1.2	G211V	Pathogenic	0.594
BRCA1	P38398-1.2	G211W	Pathogenic	0.783
BRCA1	P38398-1.2	G211Y	Pathogenic	0.766
BRCA1	P38398-1.2	T212A	Neutral	0.045
BRCA1	P38398-1.2	T212C	Neutral	0.042
BRCA1	P38398-1.2	T212D	Neutral	0.037
BRCA1	P38398-1.2	T212E	Neutral	0.05
BRCA1	P38398-1.2	T212F	Neutral	0.118
BRCA1	P38398-1.2	T212G	Neutral	0.128
BRCA1	P38398-1.2	T212H	Neutral	0.086
BRCA1	P38398-1.2	T212I	Neutral	0.068
BRCA1	P38398-1.2	T212K	Neutral	0.086
BRCA1	P38398-1.2	T212L	Neutral	0.068
BRCA1	P38398-1.2	T212M	Neutral	0.069
BRCA1	P38398-1.2	T212N	Neutral	0.027
BRCA1	P38398-1.2	T212P	Neutral	0.038
BRCA1	P38398-1.2	T212Q	Neutral	0.056
BRCA1	P38398-1.2	T212R	Neutral	0.111
BRCA1	P38398-1.2	T212S	Neutral	0.027
BRCA1	P38398-1.2	T212V	Neutral	0.032
BRCA1	P38398-1.2	T212W	Neutral	0.198
BRCA1	P38398-1.2	T212Y	Neutral	0.134
BRCA1	P38398-1.2	R213A	Neutral	0.144
BRCA1	P38398-1.2	R213C	Neutral	0.184
BRCA1	P38398-1.2	R213D	Neutral	0.127
BRCA1	P38398-1.2	R213E	Neutral	0.045
BRCA1	P38398-1.2	R213F	Neutral	0.069
BRCA1	P38398-1.2	R213G	Neutral	0.271
BRCA1	P38398-1.2	R213H	Neutral	0.036
BRCA1	P38398-1.2	R213I	Neutral	0.087
BRCA1	P38398-1.2	R213K	Neutral	0.013
BRCA1	P38398-1.2	R213L	Neutral	0.062
BRCA1	P38398-1.2	R213M	Neutral	0.044
BRCA1	P38398-1.2	R213N	Neutral	0.059
BRCA1	P38398-1.2	R213P	Neutral	0.126
BRCA1	P38398-1.2	R213Q	Neutral	0.028
BRCA1	P38398-1.2	R213S	Neutral	0.129
BRCA1	P38398-1.2	R213T	Neutral	0.086
BRCA1	P38398-1.2	R213V	Neutral	0.128
BRCA1	P38398-1.2	R213W	Neutral	0.072
BRCA1	P38398-1.2	R213Y	Neutral	0.044
BRCA1	P38398-1.2	D214A	Neutral	0.041
BRCA1	P38398-1.2	D214C	Neutral	0.038
BRCA1	P38398-1.2	D214E	Neutral	0.009
BRCA1	P38398-1.2	D214F	Neutral	0.085
BRCA1	P38398-1.2	D214G	Neutral	0.043
BRCA1	P38398-1.2	D214H	Neutral	0.031
BRCA1	P38398-1.2	D214I	Neutral	0.068
BRCA1	P38398-1.2	D214K	Neutral	0.045
BRCA1	P38398-1.2	D214L	Neutral	0.095
BRCA1	P38398-1.2	D214M	Neutral	0.068
BRCA1	P38398-1.2	D214N	Neutral	0.009
BRCA1	P38398-1.2	D214P	Neutral	0.017
BRCA1	P38398-1.2	D214Q	Neutral	0.02
BRCA1	P38398-1.2	D214R	Neutral	0.083
BRCA1	P38398-1.2	D214S	Neutral	0.018
BRCA1	P38398-1.2	D214T	Neutral	0.018
BRCA1	P38398-1.2	D214V	Neutral	0.046
BRCA1	P38398-1.2	D214W	Neutral	0.198
BRCA1	P38398-1.2	D214Y	Neutral	0.097
BRCA1	P38398-1.2	E215A	Neutral	0.396
BRCA1	P38398-1.2	E215C	Pathogenic	0.558
BRCA1	P38398-1.2	E215D	Neutral	0.116
BRCA1	P38398-1.2	E215F	Neutral	0.48
BRCA1	P38398-1.2	E215G	Pathogenic	0.591
BRCA1	P38398-1.2	E215H	Neutral	0.18
BRCA1	P38398-1.2	E215I	Neutral	0.42
BRCA1	P38398-1.2	E215K	Neutral	0.183
BRCA1	P38398-1.2	E215L	Neutral	0.42
BRCA1	P38398-1.2	E215M	Neutral	0.337
BRCA1	P38398-1.2	E215N	Neutral	0.196
BRCA1	P38398-1.2	E215P	Neutral	0.281
BRCA1	P38398-1.2	E215Q	Neutral	0.089
BRCA1	P38398-1.2	E215R	Neutral	0.301
BRCA1	P38398-1.2	E215S	Neutral	0.286
BRCA1	P38398-1.2	E215T	Neutral	0.269
BRCA1	P38398-1.2	E215V	Neutral	0.285
BRCA1	P38398-1.2	E215W	Pathogenic	0.63
BRCA1	P38398-1.2	E215Y	Neutral	0.427
BRCA1	P38398-1.2	I216A	Neutral	0.061
BRCA1	P38398-1.2	I216C	Neutral	0.042
BRCA1	P38398-1.2	I216D	Neutral	0.072
BRCA1	P38398-1.2	I216E	Neutral	0.05
BRCA1	P38398-1.2	I216F	Neutral	0.017
BRCA1	P38398-1.2	I216G	Neutral	0.228
BRCA1	P38398-1.2	I216H	Neutral	0.042
BRCA1	P38398-1.2	I216K	Neutral	0.045
BRCA1	P38398-1.2	I216L	Neutral	0.006
BRCA1	P38398-1.2	I216M	Neutral	0.009
BRCA1	P38398-1.2	I216N	Neutral	0.065
BRCA1	P38398-1.2	I216P	Neutral	0.076
BRCA1	P38398-1.2	I216Q	Neutral	0.045
BRCA1	P38398-1.2	I216R	Neutral	0.06
BRCA1	P38398-1.2	I216S	Neutral	0.076
BRCA1	P38398-1.2	I216T	Neutral	0.035
BRCA1	P38398-1.2	I216V	Neutral	0.007
BRCA1	P38398-1.2	I216W	Neutral	0.085
BRCA1	P38398-1.2	I216Y	Neutral	0.027
BRCA1	P38398-1.2	S217A	Neutral	0.009
BRCA1	P38398-1.2	S217C	Neutral	0.021
BRCA1	P38398-1.2	S217D	Neutral	0.016
BRCA1	P38398-1.2	S217E	Neutral	0.024
BRCA1	P38398-1.2	S217F	Neutral	0.082
BRCA1	P38398-1.2	S217G	Neutral	0.019
BRCA1	P38398-1.2	S217H	Neutral	0.042
BRCA1	P38398-1.2	S217I	Neutral	0.065
BRCA1	P38398-1.2	S217K	Neutral	0.042
BRCA1	P38398-1.2	S217L	Neutral	0.065
BRCA1	P38398-1.2	S217M	Neutral	0.047
BRCA1	P38398-1.2	S217N	Neutral	0.013
BRCA1	P38398-1.2	S217P	Neutral	0.023
BRCA1	P38398-1.2	S217Q	Neutral	0.027
BRCA1	P38398-1.2	S217R	Neutral	0.077
BRCA1	P38398-1.2	S217T	Neutral	0.012
BRCA1	P38398-1.2	S217V	Neutral	0.044
BRCA1	P38398-1.2	S217W	Neutral	0.191
BRCA1	P38398-1.2	S217Y	Neutral	0.093
BRCA1	P38398-1.2	L218A	Neutral	0.202
BRCA1	P38398-1.2	L218C	Neutral	0.144
BRCA1	P38398-1.2	L218D	Neutral	0.303
BRCA1	P38398-1.2	L218E	Neutral	0.168
BRCA1	P38398-1.2	L218F	Neutral	0.061
BRCA1	P38398-1.2	L218G	Pathogenic	0.534
BRCA1	P38398-1.2	L218H	Neutral	0.144
BRCA1	P38398-1.2	L218I	Neutral	0.024
BRCA1	P38398-1.2	L218K	Neutral	0.113
BRCA1	P38398-1.2	L218M	Neutral	0.024
BRCA1	P38398-1.2	L218N	Neutral	0.213
BRCA1	P38398-1.2	L218P	Neutral	0.241
BRCA1	P38398-1.2	L218Q	Neutral	0.113
BRCA1	P38398-1.2	L218R	Neutral	0.146
BRCA1	P38398-1.2	L218S	Neutral	0.241
BRCA1	P38398-1.2	L218T	Neutral	0.124
BRCA1	P38398-1.2	L218V	Neutral	0.051
BRCA1	P38398-1.2	L218W	Neutral	0.199
BRCA1	P38398-1.2	L218Y	Neutral	0.095
BRCA1	P38398-1.2	D219A	Neutral	0.028
BRCA1	P38398-1.2	D219C	Neutral	0.026
BRCA1	P38398-1.2	D219E	Neutral	0.006
BRCA1	P38398-1.2	D219F	Neutral	0.058
BRCA1	P38398-1.2	D219G	Neutral	0.029
BRCA1	P38398-1.2	D219H	Neutral	0.021
BRCA1	P38398-1.2	D219I	Neutral	0.046
BRCA1	P38398-1.2	D219K	Neutral	0.03
BRCA1	P38398-1.2	D219L	Neutral	0.065
BRCA1	P38398-1.2	D219M	Neutral	0.047
BRCA1	P38398-1.2	D219N	Neutral	0.006
BRCA1	P38398-1.2	D219P	Neutral	0.012
BRCA1	P38398-1.2	D219Q	Neutral	0.013
BRCA1	P38398-1.2	D219R	Neutral	0.056
BRCA1	P38398-1.2	D219S	Neutral	0.012
BRCA1	P38398-1.2	D219T	Neutral	0.012
BRCA1	P38398-1.2	D219V	Neutral	0.031
BRCA1	P38398-1.2	D219W	Neutral	0.141
BRCA1	P38398-1.2	D219Y	Neutral	0.067
BRCA1	P38398-1.2	S220A	Neutral	0.023
BRCA1	P38398-1.2	S220C	Neutral	0.053
BRCA1	P38398-1.2	S220D	Neutral	0.042
BRCA1	P38398-1.2	S220E	Neutral	0.061
BRCA1	P38398-1.2	S220F	Neutral	0.19
BRCA1	P38398-1.2	S220G	Neutral	0.049
BRCA1	P38398-1.2	S220H	Neutral	0.103
BRCA1	P38398-1.2	S220I	Neutral	0.155
BRCA1	P38398-1.2	S220K	Neutral	0.103
BRCA1	P38398-1.2	S220L	Neutral	0.155
BRCA1	P38398-1.2	S220M	Neutral	0.114
BRCA1	P38398-1.2	S220N	Neutral	0.033
BRCA1	P38398-1.2	S220P	Neutral	0.058
BRCA1	P38398-1.2	S220Q	Neutral	0.068
BRCA1	P38398-1.2	S220R	Neutral	0.181
BRCA1	P38398-1.2	S220T	Neutral	0.031
BRCA1	P38398-1.2	S220V	Neutral	0.108
BRCA1	P38398-1.2	S220W	Neutral	0.383
BRCA1	P38398-1.2	S220Y	Neutral	0.214
BRCA1	P38398-1.2	A221C	Neutral	0.031
BRCA1	P38398-1.2	A221D	Neutral	0.068
BRCA1	P38398-1.2	A221E	Neutral	0.071
BRCA1	P38398-1.2	A221F	Neutral	0.162
BRCA1	P38398-1.2	A221G	Neutral	0.031
BRCA1	P38398-1.2	A221H	Neutral	0.12
BRCA1	P38398-1.2	A221I	Neutral	0.095
BRCA1	P38398-1.2	A221K	Neutral	0.119
BRCA1	P38398-1.2	A221L	Neutral	0.096
BRCA1	P38398-1.2	A221M	Neutral	0.096
BRCA1	P38398-1.2	A221N	Neutral	0.076
BRCA1	P38398-1.2	A221P	Neutral	0.048
BRCA1	P38398-1.2	A221Q	Neutral	0.079
BRCA1	P38398-1.2	A221R	Neutral	0.153
BRCA1	P38398-1.2	A221S	Neutral	0.016
BRCA1	P38398-1.2	A221T	Neutral	0.036
BRCA1	P38398-1.2	A221V	Neutral	0.046
BRCA1	P38398-1.2	A221W	Neutral	0.34
BRCA1	P38398-1.2	A221Y	Neutral	0.184
BRCA1	P38398-1.2	K222A	Neutral	0.257
BRCA1	P38398-1.2	K222C	Neutral	0.317
BRCA1	P38398-1.2	K222D	Neutral	0.172
BRCA1	P38398-1.2	K222E	Neutral	0.063
BRCA1	P38398-1.2	K222F	Neutral	0.133
BRCA1	P38398-1.2	K222G	Neutral	0.433
BRCA1	P38398-1.2	K222H	Neutral	0.101
BRCA1	P38398-1.2	K222I	Neutral	0.164
BRCA1	P38398-1.2	K222L	Neutral	0.12
BRCA1	P38398-1.2	K222M	Neutral	0.088
BRCA1	P38398-1.2	K222N	Neutral	0.114
BRCA1	P38398-1.2	K222P	Neutral	0.171
BRCA1	P38398-1.2	K222Q	Neutral	0.056
BRCA1	P38398-1.2	K222R	Neutral	0.034
BRCA1	P38398-1.2	K222S	Neutral	0.175
BRCA1	P38398-1.2	K222T	Neutral	0.163
BRCA1	P38398-1.2	K222V	Neutral	0.174
BRCA1	P38398-1.2	K222W	Neutral	0.221
BRCA1	P38398-1.2	K222Y	Neutral	0.11
BRCA1	P38398-1.2	K223A	Neutral	0.093
BRCA1	P38398-1.2	K223C	Neutral	0.121
BRCA1	P38398-1.2	K223D	Neutral	0.058
BRCA1	P38398-1.2	K223E	Neutral	0.019
BRCA1	P38398-1.2	K223F	Neutral	0.044
BRCA1	P38398-1.2	K223G	Neutral	0.185
BRCA1	P38398-1.2	K223H	Neutral	0.032
BRCA1	P38398-1.2	K223I	Neutral	0.055
BRCA1	P38398-1.2	K223L	Neutral	0.039
BRCA1	P38398-1.2	K223M	Neutral	0.028
BRCA1	P38398-1.2	K223N	Neutral	0.037
BRCA1	P38398-1.2	K223P	Neutral	0.058
BRCA1	P38398-1.2	K223Q	Neutral	0.017
BRCA1	P38398-1.2	K223R	Neutral	0.01
BRCA1	P38398-1.2	K223S	Neutral	0.059
BRCA1	P38398-1.2	K223T	Neutral	0.055
BRCA1	P38398-1.2	K223V	Neutral	0.059
BRCA1	P38398-1.2	K223W	Neutral	0.078
BRCA1	P38398-1.2	K223Y	Neutral	0.036
BRCA1	P38398-1.2	A224C	Neutral	0.056
BRCA1	P38398-1.2	A224D	Neutral	0.12
BRCA1	P38398-1.2	A224E	Neutral	0.124
BRCA1	P38398-1.2	A224F	Neutral	0.265
BRCA1	P38398-1.2	A224G	Neutral	0.057
BRCA1	P38398-1.2	A224H	Neutral	0.202
BRCA1	P38398-1.2	A224I	Neutral	0.164
BRCA1	P38398-1.2	A224K	Neutral	0.201
BRCA1	P38398-1.2	A224L	Neutral	0.164
BRCA1	P38398-1.2	A224M	Neutral	0.165
BRCA1	P38398-1.2	A224N	Neutral	0.133
BRCA1	P38398-1.2	A224P	Neutral	0.086
BRCA1	P38398-1.2	A224Q	Neutral	0.138
BRCA1	P38398-1.2	A224R	Neutral	0.251
BRCA1	P38398-1.2	A224S	Neutral	0.03
BRCA1	P38398-1.2	A224T	Neutral	0.066
BRCA1	P38398-1.2	A224V	Neutral	0.083
BRCA1	P38398-1.2	A224W	Neutral	0.489
BRCA1	P38398-1.2	A224Y	Neutral	0.295
BRCA1	P38398-1.2	A225C	Neutral	0.068
BRCA1	P38398-1.2	A225D	Neutral	0.143
BRCA1	P38398-1.2	A225E	Neutral	0.148
BRCA1	P38398-1.2	A225F	Neutral	0.305
BRCA1	P38398-1.2	A225G	Neutral	0.068
BRCA1	P38398-1.2	A225H	Neutral	0.236
BRCA1	P38398-1.2	A225I	Neutral	0.193
BRCA1	P38398-1.2	A225K	Neutral	0.235
BRCA1	P38398-1.2	A225L	Neutral	0.193
BRCA1	P38398-1.2	A225M	Neutral	0.195
BRCA1	P38398-1.2	A225N	Neutral	0.157
BRCA1	P38398-1.2	A225P	Neutral	0.103
BRCA1	P38398-1.2	A225Q	Neutral	0.163
BRCA1	P38398-1.2	A225R	Neutral	0.29
BRCA1	P38398-1.2	A225S	Neutral	0.037
BRCA1	P38398-1.2	A225T	Neutral	0.079
BRCA1	P38398-1.2	A225V	Neutral	0.099
BRCA1	P38398-1.2	A225W	Pathogenic	0.539
BRCA1	P38398-1.2	A225Y	Neutral	0.338
BRCA1	P38398-1.2	C226A	Neutral	0.491
BRCA1	P38398-1.2	C226D	Pathogenic	0.674
BRCA1	P38398-1.2	C226E	Pathogenic	0.816
BRCA1	P38398-1.2	C226F	Pathogenic	0.795
BRCA1	P38398-1.2	C226G	Pathogenic	0.814
BRCA1	P38398-1.2	C226H	Pathogenic	0.793
BRCA1	P38398-1.2	C226I	Pathogenic	0.679
BRCA1	P38398-1.2	C226K	Pathogenic	0.845
BRCA1	P38398-1.2	C226L	Pathogenic	0.679
BRCA1	P38398-1.2	C226M	Pathogenic	0.681
BRCA1	P38398-1.2	C226N	Pathogenic	0.698
BRCA1	P38398-1.2	C226P	Pathogenic	0.675
BRCA1	P38398-1.2	C226Q	Pathogenic	0.777
BRCA1	P38398-1.2	C226R	Pathogenic	0.879
BRCA1	P38398-1.2	C226S	Pathogenic	0.547
BRCA1	P38398-1.2	C226T	Pathogenic	0.515
BRCA1	P38398-1.2	C226V	Pathogenic	0.584
BRCA1	P38398-1.2	C226W	Pathogenic	0.878
BRCA1	P38398-1.2	C226Y	Pathogenic	0.818
BRCA1	P38398-1.2	E227A	Neutral	0.244
BRCA1	P38398-1.2	E227C	Neutral	0.384
BRCA1	P38398-1.2	E227D	Neutral	0.061
BRCA1	P38398-1.2	E227F	Neutral	0.313
BRCA1	P38398-1.2	E227G	Neutral	0.416
BRCA1	P38398-1.2	E227H	Neutral	0.098
BRCA1	P38398-1.2	E227I	Neutral	0.263
BRCA1	P38398-1.2	E227K	Neutral	0.099
BRCA1	P38398-1.2	E227L	Neutral	0.263
BRCA1	P38398-1.2	E227M	Neutral	0.2
BRCA1	P38398-1.2	E227N	Neutral	0.107
BRCA1	P38398-1.2	E227P	Neutral	0.161
BRCA1	P38398-1.2	E227Q	Neutral	0.046
BRCA1	P38398-1.2	E227R	Neutral	0.175
BRCA1	P38398-1.2	E227S	Neutral	0.165
BRCA1	P38398-1.2	E227T	Neutral	0.153
BRCA1	P38398-1.2	E227V	Neutral	0.164
BRCA1	P38398-1.2	E227W	Neutral	0.457
BRCA1	P38398-1.2	E227Y	Neutral	0.269
BRCA1	P38398-1.2	F228A	Neutral	0.378
BRCA1	P38398-1.2	F228C	Neutral	0.288
BRCA1	P38398-1.2	F228D	Neutral	0.335
BRCA1	P38398-1.2	F228E	Neutral	0.253
BRCA1	P38398-1.2	F228G	Pathogenic	0.57
BRCA1	P38398-1.2	F228H	Neutral	0.12
BRCA1	P38398-1.2	F228I	Neutral	0.079
BRCA1	P38398-1.2	F228K	Neutral	0.159
BRCA1	P38398-1.2	F228L	Neutral	0.078
BRCA1	P38398-1.2	F228M	Neutral	0.078
BRCA1	P38398-1.2	F228N	Neutral	0.311
BRCA1	P38398-1.2	F228P	Neutral	0.432
BRCA1	P38398-1.2	F228Q	Neutral	0.234
BRCA1	P38398-1.2	F228R	Neutral	0.201
BRCA1	P38398-1.2	F228S	Neutral	0.346
BRCA1	P38398-1.2	F228T	Neutral	0.254
BRCA1	P38398-1.2	F228V	Neutral	0.156
BRCA1	P38398-1.2	F228W	Neutral	0.079
BRCA1	P38398-1.2	F228Y	Neutral	0.025
BRCA1	P38398-1.2	S229A	Neutral	0.208
BRCA1	P38398-1.2	S229C	Neutral	0.386
BRCA1	P38398-1.2	S229D	Neutral	0.329
BRCA1	P38398-1.2	S229E	Neutral	0.423
BRCA1	P38398-1.2	S229F	Pathogenic	0.725
BRCA1	P38398-1.2	S229G	Neutral	0.367
BRCA1	P38398-1.2	S229H	Pathogenic	0.565
BRCA1	P38398-1.2	S229I	Pathogenic	0.674
BRCA1	P38398-1.2	S229K	Pathogenic	0.565
BRCA1	P38398-1.2	S229L	Pathogenic	0.675
BRCA1	P38398-1.2	S229M	Pathogenic	0.592
BRCA1	P38398-1.2	S229N	Neutral	0.276
BRCA1	P38398-1.2	S229P	Neutral	0.408
BRCA1	P38398-1.2	S229Q	Neutral	0.452
BRCA1	P38398-1.2	S229R	Pathogenic	0.714
BRCA1	P38398-1.2	S229T	Neutral	0.264
BRCA1	P38398-1.2	S229V	Pathogenic	0.578
BRCA1	P38398-1.2	S229W	Pathogenic	0.875
BRCA1	P38398-1.2	S229Y	Pathogenic	0.754
BRCA1	P38398-1.2	E230A	Neutral	0.205
BRCA1	P38398-1.2	E230C	Neutral	0.332
BRCA1	P38398-1.2	E230D	Neutral	0.049
BRCA1	P38398-1.2	E230F	Neutral	0.267
BRCA1	P38398-1.2	E230G	Neutral	0.363
BRCA1	P38398-1.2	E230H	Neutral	0.08
BRCA1	P38398-1.2	E230I	Neutral	0.222
BRCA1	P38398-1.2	E230K	Neutral	0.081
BRCA1	P38398-1.2	E230L	Neutral	0.222
BRCA1	P38398-1.2	E230M	Neutral	0.167
BRCA1	P38398-1.2	E230N	Neutral	0.087
BRCA1	P38398-1.2	E230P	Neutral	0.133
BRCA1	P38398-1.2	E230Q	Neutral	0.037
BRCA1	P38398-1.2	E230R	Neutral	0.145
BRCA1	P38398-1.2	E230S	Neutral	0.136
BRCA1	P38398-1.2	E230T	Neutral	0.127
BRCA1	P38398-1.2	E230V	Neutral	0.136
BRCA1	P38398-1.2	E230W	Neutral	0.402
BRCA1	P38398-1.2	E230Y	Neutral	0.227
BRCA1	P38398-1.2	T231A	Neutral	0.058
BRCA1	P38398-1.2	T231C	Neutral	0.054
BRCA1	P38398-1.2	T231D	Neutral	0.048
BRCA1	P38398-1.2	T231E	Neutral	0.065
BRCA1	P38398-1.2	T231F	Neutral	0.15
BRCA1	P38398-1.2	T231G	Neutral	0.162
BRCA1	P38398-1.2	T231H	Neutral	0.11
BRCA1	P38398-1.2	T231I	Neutral	0.087
BRCA1	P38398-1.2	T231K	Neutral	0.11
BRCA1	P38398-1.2	T231L	Neutral	0.088
BRCA1	P38398-1.2	T231M	Neutral	0.088
BRCA1	P38398-1.2	T231N	Neutral	0.035
BRCA1	P38398-1.2	T231P	Neutral	0.05
BRCA1	P38398-1.2	T231Q	Neutral	0.073
BRCA1	P38398-1.2	T231R	Neutral	0.141
BRCA1	P38398-1.2	T231S	Neutral	0.036
BRCA1	P38398-1.2	T231V	Neutral	0.042
BRCA1	P38398-1.2	T231W	Neutral	0.245
BRCA1	P38398-1.2	T231Y	Neutral	0.17
BRCA1	P38398-1.2	D232A	Neutral	0.049
BRCA1	P38398-1.2	D232C	Neutral	0.046
BRCA1	P38398-1.2	D232E	Neutral	0.011
BRCA1	P38398-1.2	D232F	Neutral	0.102
BRCA1	P38398-1.2	D232G	Neutral	0.052
BRCA1	P38398-1.2	D232H	Neutral	0.037
BRCA1	P38398-1.2	D232I	Neutral	0.081
BRCA1	P38398-1.2	D232K	Neutral	0.054
BRCA1	P38398-1.2	D232L	Neutral	0.113
BRCA1	P38398-1.2	D232M	Neutral	0.082
BRCA1	P38398-1.2	D232N	Neutral	0.011
BRCA1	P38398-1.2	D232P	Neutral	0.021
BRCA1	P38398-1.2	D232Q	Neutral	0.024
BRCA1	P38398-1.2	D232R	Neutral	0.099
BRCA1	P38398-1.2	D232S	Neutral	0.022
BRCA1	P38398-1.2	D232T	Neutral	0.022
BRCA1	P38398-1.2	D232V	Neutral	0.055
BRCA1	P38398-1.2	D232W	Neutral	0.231
BRCA1	P38398-1.2	D232Y	Neutral	0.116
BRCA1	P38398-1.2	V233A	Neutral	0.021
BRCA1	P38398-1.2	V233C	Neutral	0.021
BRCA1	P38398-1.2	V233D	Neutral	0.036
BRCA1	P38398-1.2	V233E	Neutral	0.02
BRCA1	P38398-1.2	V233F	Neutral	0.026
BRCA1	P38398-1.2	V233G	Neutral	0.09
BRCA1	P38398-1.2	V233H	Neutral	0.036
BRCA1	P38398-1.2	V233I	Neutral	0.005
BRCA1	P38398-1.2	V233K	Neutral	0.036
BRCA1	P38398-1.2	V233L	Neutral	0.01
BRCA1	P38398-1.2	V233M	Neutral	0.01
BRCA1	P38398-1.2	V233N	Neutral	0.033
BRCA1	P38398-1.2	V233P	Neutral	0.027
BRCA1	P38398-1.2	V233Q	Neutral	0.023
BRCA1	P38398-1.2	V233R	Neutral	0.066
BRCA1	P38398-1.2	V233S	Neutral	0.038
BRCA1	P38398-1.2	V233T	Neutral	0.012
BRCA1	P38398-1.2	V233W	Neutral	0.092
BRCA1	P38398-1.2	V233Y	Neutral	0.03
BRCA1	P38398-1.2	T234A	Neutral	0.027
BRCA1	P38398-1.2	T234C	Neutral	0.025
BRCA1	P38398-1.2	T234D	Neutral	0.022
BRCA1	P38398-1.2	T234E	Neutral	0.03
BRCA1	P38398-1.2	T234F	Neutral	0.074
BRCA1	P38398-1.2	T234G	Neutral	0.08
BRCA1	P38398-1.2	T234H	Neutral	0.053
BRCA1	P38398-1.2	T234I	Neutral	0.041
BRCA1	P38398-1.2	T234K	Neutral	0.053
BRCA1	P38398-1.2	T234L	Neutral	0.042
BRCA1	P38398-1.2	T234M	Neutral	0.042
BRCA1	P38398-1.2	T234N	Neutral	0.016
BRCA1	P38398-1.2	T234P	Neutral	0.023
BRCA1	P38398-1.2	T234Q	Neutral	0.034
BRCA1	P38398-1.2	T234R	Neutral	0.069
BRCA1	P38398-1.2	T234S	Neutral	0.016
BRCA1	P38398-1.2	T234V	Neutral	0.02
BRCA1	P38398-1.2	T234W	Neutral	0.128
BRCA1	P38398-1.2	T234Y	Neutral	0.085
BRCA1	P38398-1.2	N235A	Neutral	0.053
BRCA1	P38398-1.2	N235C	Neutral	0.049
BRCA1	P38398-1.2	N235D	Neutral	0.011
BRCA1	P38398-1.2	N235E	Neutral	0.019
BRCA1	P38398-1.2	N235F	Neutral	0.088
BRCA1	P38398-1.2	N235G	Neutral	0.039
BRCA1	P38398-1.2	N235H	Neutral	0.016
BRCA1	P38398-1.2	N235I	Neutral	0.071
BRCA1	P38398-1.2	N235K	Neutral	0.033
BRCA1	P38398-1.2	N235L	Neutral	0.071
BRCA1	P38398-1.2	N235M	Neutral	0.051
BRCA1	P38398-1.2	N235P	Neutral	0.032
BRCA1	P38398-1.2	N235Q	Neutral	0.021
BRCA1	P38398-1.2	N235R	Neutral	0.043
BRCA1	P38398-1.2	N235S	Neutral	0.016
BRCA1	P38398-1.2	N235T	Neutral	0.015
BRCA1	P38398-1.2	N235V	Neutral	0.048
BRCA1	P38398-1.2	N235W	Neutral	0.205
BRCA1	P38398-1.2	N235Y	Neutral	0.073
BRCA1	P38398-1.2	T236A	Neutral	0.005
BRCA1	P38398-1.2	T236C	Neutral	0.005
BRCA1	P38398-1.2	T236D	Neutral	0.005
BRCA1	P38398-1.2	T236E	Neutral	0.006
BRCA1	P38398-1.2	T236F	Neutral	0.015
BRCA1	P38398-1.2	T236G	Neutral	0.017
BRCA1	P38398-1.2	T236H	Neutral	0.011
BRCA1	P38398-1.2	T236I	Neutral	0.008
BRCA1	P38398-1.2	T236K	Neutral	0.011
BRCA1	P38398-1.2	T236L	Neutral	0.008
BRCA1	P38398-1.2	T236M	Neutral	0.009
BRCA1	P38398-1.2	T236N	Neutral	0.003
BRCA1	P38398-1.2	T236P	Neutral	0.005
BRCA1	P38398-1.2	T236Q	Neutral	0.007
BRCA1	P38398-1.2	T236R	Neutral	0.014
BRCA1	P38398-1.2	T236S	Neutral	0.003
BRCA1	P38398-1.2	T236V	Neutral	0.004
BRCA1	P38398-1.2	T236W	Neutral	0.028
BRCA1	P38398-1.2	T236Y	Neutral	0.018
BRCA1	P38398-1.2	E237A	Neutral	0.038
BRCA1	P38398-1.2	E237C	Neutral	0.072
BRCA1	P38398-1.2	E237D	Neutral	0.008
BRCA1	P38398-1.2	E237F	Neutral	0.053
BRCA1	P38398-1.2	E237G	Neutral	0.081
BRCA1	P38398-1.2	E237H	Neutral	0.013
BRCA1	P38398-1.2	E237I	Neutral	0.042
BRCA1	P38398-1.2	E237K	Neutral	0.013
BRCA1	P38398-1.2	E237L	Neutral	0.042
BRCA1	P38398-1.2	E237M	Neutral	0.03
BRCA1	P38398-1.2	E237N	Neutral	0.015
BRCA1	P38398-1.2	E237P	Neutral	0.023
BRCA1	P38398-1.2	E237Q	Neutral	0.006
BRCA1	P38398-1.2	E237R	Neutral	0.026
BRCA1	P38398-1.2	E237S	Neutral	0.024
BRCA1	P38398-1.2	E237T	Neutral	0.022
BRCA1	P38398-1.2	E237V	Neutral	0.024
BRCA1	P38398-1.2	E237W	Neutral	0.094
BRCA1	P38398-1.2	E237Y	Neutral	0.043
BRCA1	P38398-1.2	H238A	Neutral	0.056
BRCA1	P38398-1.2	H238C	Neutral	0.053
BRCA1	P38398-1.2	H238D	Neutral	0.023
BRCA1	P38398-1.2	H238E	Neutral	0.011
BRCA1	P38398-1.2	H238F	Neutral	0.019
BRCA1	P38398-1.2	H238G	Neutral	0.083
BRCA1	P38398-1.2	H238I	Neutral	0.03
BRCA1	P38398-1.2	H238K	Neutral	0.019
BRCA1	P38398-1.2	H238L	Neutral	0.03
BRCA1	P38398-1.2	H238M	Neutral	0.021
BRCA1	P38398-1.2	H238N	Neutral	0.01
BRCA1	P38398-1.2	H238P	Neutral	0.034
BRCA1	P38398-1.2	H238Q	Neutral	0.01
BRCA1	P38398-1.2	H238R	Neutral	0.017
BRCA1	P38398-1.2	H238S	Neutral	0.035
BRCA1	P38398-1.2	H238T	Neutral	0.032
BRCA1	P38398-1.2	H238V	Neutral	0.035
BRCA1	P38398-1.2	H238W	Neutral	0.048
BRCA1	P38398-1.2	H238Y	Neutral	0.007
BRCA1	P38398-1.2	H239A	Neutral	0.162
BRCA1	P38398-1.2	H239C	Neutral	0.152
BRCA1	P38398-1.2	H239D	Neutral	0.072
BRCA1	P38398-1.2	H239E	Neutral	0.035
BRCA1	P38398-1.2	H239F	Neutral	0.058
BRCA1	P38398-1.2	H239G	Neutral	0.227
BRCA1	P38398-1.2	H239I	Neutral	0.09
BRCA1	P38398-1.2	H239K	Neutral	0.058
BRCA1	P38398-1.2	H239L	Neutral	0.09
BRCA1	P38398-1.2	H239M	Neutral	0.065
BRCA1	P38398-1.2	H239N	Neutral	0.033
BRCA1	P38398-1.2	H239P	Neutral	0.103
BRCA1	P38398-1.2	H239Q	Neutral	0.032
BRCA1	P38398-1.2	H239R	Neutral	0.054
BRCA1	P38398-1.2	H239S	Neutral	0.105
BRCA1	P38398-1.2	H239T	Neutral	0.098
BRCA1	P38398-1.2	H239V	Neutral	0.105
BRCA1	P38398-1.2	H239W	Neutral	0.14
BRCA1	P38398-1.2	H239Y	Neutral	0.023
BRCA1	P38398-1.2	Q240A	Neutral	0.26
BRCA1	P38398-1.2	Q240C	Neutral	0.321
BRCA1	P38398-1.2	Q240D	Neutral	0.125
BRCA1	P38398-1.2	Q240E	Neutral	0.044
BRCA1	P38398-1.2	Q240F	Neutral	0.285
BRCA1	P38398-1.2	Q240G	Neutral	0.437
BRCA1	P38398-1.2	Q240H	Neutral	0.086
BRCA1	P38398-1.2	Q240I	Neutral	0.237
BRCA1	P38398-1.2	Q240K	Neutral	0.087
BRCA1	P38398-1.2	Q240L	Neutral	0.178
BRCA1	P38398-1.2	Q240M	Neutral	0.096
BRCA1	P38398-1.2	Q240N	Neutral	0.114
BRCA1	P38398-1.2	Q240P	Neutral	0.173
BRCA1	P38398-1.2	Q240R	Neutral	0.112
BRCA1	P38398-1.2	Q240S	Neutral	0.177
BRCA1	P38398-1.2	Q240T	Neutral	0.165
BRCA1	P38398-1.2	Q240V	Neutral	0.176
BRCA1	P38398-1.2	Q240W	Neutral	0.338
BRCA1	P38398-1.2	Q240Y	Neutral	0.182
BRCA1	P38398-1.2	P241A	Neutral	0.014
BRCA1	P38398-1.2	P241C	Neutral	0.019
BRCA1	P38398-1.2	P241D	Neutral	0.009
BRCA1	P38398-1.2	P241E	Neutral	0.013
BRCA1	P38398-1.2	P241F	Neutral	0.064
BRCA1	P38398-1.2	P241G	Neutral	0.03
BRCA1	P38398-1.2	P241H	Neutral	0.022
BRCA1	P38398-1.2	P241I	Neutral	0.036
BRCA1	P38398-1.2	P241K	Neutral	0.022
BRCA1	P38398-1.2	P241L	Neutral	0.036
BRCA1	P38398-1.2	P241M	Neutral	0.026
BRCA1	P38398-1.2	P241N	Neutral	0.014
BRCA1	P38398-1.2	P241Q	Neutral	0.014
BRCA1	P38398-1.2	P241R	Neutral	0.042
BRCA1	P38398-1.2	P241S	Neutral	0.012
BRCA1	P38398-1.2	P241T	Neutral	0.009
BRCA1	P38398-1.2	P241V	Neutral	0.017
BRCA1	P38398-1.2	P241W	Neutral	0.113
BRCA1	P38398-1.2	P241Y	Neutral	0.053
BRCA1	P38398-1.2	S242A	Neutral	0.032
BRCA1	P38398-1.2	S242C	Neutral	0.074
BRCA1	P38398-1.2	S242D	Neutral	0.059
BRCA1	P38398-1.2	S242E	Neutral	0.085
BRCA1	P38398-1.2	S242F	Neutral	0.251
BRCA1	P38398-1.2	S242G	Neutral	0.069
BRCA1	P38398-1.2	S242H	Neutral	0.142
BRCA1	P38398-1.2	S242I	Neutral	0.208
BRCA1	P38398-1.2	S242K	Neutral	0.141
BRCA1	P38398-1.2	S242L	Neutral	0.208
BRCA1	P38398-1.2	S242M	Neutral	0.156
BRCA1	P38398-1.2	S242N	Neutral	0.046
BRCA1	P38398-1.2	S242P	Neutral	0.081
BRCA1	P38398-1.2	S242Q	Neutral	0.095
BRCA1	P38398-1.2	S242R	Neutral	0.24
BRCA1	P38398-1.2	S242T	Neutral	0.044
BRCA1	P38398-1.2	S242V	Neutral	0.148
BRCA1	P38398-1.2	S242W	Neutral	0.471
BRCA1	P38398-1.2	S242Y	Neutral	0.28
BRCA1	P38398-1.2	N243A	Neutral	0.031
BRCA1	P38398-1.2	N243C	Neutral	0.029
BRCA1	P38398-1.2	N243D	Neutral	0.006
BRCA1	P38398-1.2	N243E	Neutral	0.011
BRCA1	P38398-1.2	N243F	Neutral	0.054
BRCA1	P38398-1.2	N243G	Neutral	0.024
BRCA1	P38398-1.2	N243H	Neutral	0.009
BRCA1	P38398-1.2	N243I	Neutral	0.043
BRCA1	P38398-1.2	N243K	Neutral	0.019
BRCA1	P38398-1.2	N243L	Neutral	0.043
BRCA1	P38398-1.2	N243M	Neutral	0.03
BRCA1	P38398-1.2	N243P	Neutral	0.019
BRCA1	P38398-1.2	N243Q	Neutral	0.012
BRCA1	P38398-1.2	N243R	Neutral	0.026
BRCA1	P38398-1.2	N243S	Neutral	0.01
BRCA1	P38398-1.2	N243T	Neutral	0.009
BRCA1	P38398-1.2	N243V	Neutral	0.029
BRCA1	P38398-1.2	N243W	Neutral	0.131
BRCA1	P38398-1.2	N243Y	Neutral	0.044
BRCA1	P38398-1.2	N244A	Neutral	0.031
BRCA1	P38398-1.2	N244C	Neutral	0.029
BRCA1	P38398-1.2	N244D	Neutral	0.006
BRCA1	P38398-1.2	N244E	Neutral	0.011
BRCA1	P38398-1.2	N244F	Neutral	0.052
BRCA1	P38398-1.2	N244G	Neutral	0.023
BRCA1	P38398-1.2	N244H	Neutral	0.009
BRCA1	P38398-1.2	N244I	Neutral	0.041
BRCA1	P38398-1.2	N244K	Neutral	0.019
BRCA1	P38398-1.2	N244L	Neutral	0.042
BRCA1	P38398-1.2	N244M	Neutral	0.029
BRCA1	P38398-1.2	N244P	Neutral	0.018
BRCA1	P38398-1.2	N244Q	Neutral	0.012
BRCA1	P38398-1.2	N244R	Neutral	0.025
BRCA1	P38398-1.2	N244S	Neutral	0.009
BRCA1	P38398-1.2	N244T	Neutral	0.009
BRCA1	P38398-1.2	N244V	Neutral	0.028
BRCA1	P38398-1.2	N244W	Neutral	0.128
BRCA1	P38398-1.2	N244Y	Neutral	0.043
BRCA1	P38398-1.2	D245A	Neutral	0.326
BRCA1	P38398-1.2	D245C	Neutral	0.311
BRCA1	P38398-1.2	D245E	Neutral	0.091
BRCA1	P38398-1.2	D245F	Pathogenic	0.513
BRCA1	P38398-1.2	D245G	Neutral	0.34
BRCA1	P38398-1.2	D245H	Neutral	0.265
BRCA1	P38398-1.2	D245I	Neutral	0.452
BRCA1	P38398-1.2	D245K	Neutral	0.348
BRCA1	P38398-1.2	D245L	Pathogenic	0.544
BRCA1	P38398-1.2	D245M	Neutral	0.455
BRCA1	P38398-1.2	D245N	Neutral	0.098
BRCA1	P38398-1.2	D245P	Neutral	0.167
BRCA1	P38398-1.2	D245Q	Neutral	0.188
BRCA1	P38398-1.2	D245R	Pathogenic	0.506
BRCA1	P38398-1.2	D245S	Neutral	0.171
BRCA1	P38398-1.2	D245T	Neutral	0.171
BRCA1	P38398-1.2	D245V	Neutral	0.354
BRCA1	P38398-1.2	D245W	Pathogenic	0.737
BRCA1	P38398-1.2	D245Y	Pathogenic	0.551
BRCA1	P38398-1.2	L246A	Neutral	0.137
BRCA1	P38398-1.2	L246C	Neutral	0.095
BRCA1	P38398-1.2	L246D	Neutral	0.213
BRCA1	P38398-1.2	L246E	Neutral	0.112
BRCA1	P38398-1.2	L246F	Neutral	0.039
BRCA1	P38398-1.2	L246G	Neutral	0.417
BRCA1	P38398-1.2	L246H	Neutral	0.095
BRCA1	P38398-1.2	L246I	Neutral	0.015
BRCA1	P38398-1.2	L246K	Neutral	0.074
BRCA1	P38398-1.2	L246M	Neutral	0.015
BRCA1	P38398-1.2	L246N	Neutral	0.145
BRCA1	P38398-1.2	L246P	Neutral	0.166
BRCA1	P38398-1.2	L246Q	Neutral	0.074
BRCA1	P38398-1.2	L246R	Neutral	0.096
BRCA1	P38398-1.2	L246S	Neutral	0.165
BRCA1	P38398-1.2	L246T	Neutral	0.082
BRCA1	P38398-1.2	L246V	Neutral	0.032
BRCA1	P38398-1.2	L246W	Neutral	0.134
BRCA1	P38398-1.2	L246Y	Neutral	0.062
BRCA1	P38398-1.2	N247A	Neutral	0.01
BRCA1	P38398-1.2	N247C	Neutral	0.01
BRCA1	P38398-1.2	N247D	Neutral	0.002
BRCA1	P38398-1.2	N247E	Neutral	0.004
BRCA1	P38398-1.2	N247F	Neutral	0.018
BRCA1	P38398-1.2	N247G	Neutral	0.008
BRCA1	P38398-1.2	N247H	Neutral	0.003
BRCA1	P38398-1.2	N247I	Neutral	0.014
BRCA1	P38398-1.2	N247K	Neutral	0.006
BRCA1	P38398-1.2	N247L	Neutral	0.014
BRCA1	P38398-1.2	N247M	Neutral	0.01
BRCA1	P38398-1.2	N247P	Neutral	0.006
BRCA1	P38398-1.2	N247Q	Neutral	0.004
BRCA1	P38398-1.2	N247R	Neutral	0.008
BRCA1	P38398-1.2	N247S	Neutral	0.003
BRCA1	P38398-1.2	N247T	Neutral	0.003
BRCA1	P38398-1.2	N247V	Neutral	0.009
BRCA1	P38398-1.2	N247W	Neutral	0.046
BRCA1	P38398-1.2	N247Y	Neutral	0.015
BRCA1	P38398-1.2	T248A	Neutral	0.047
BRCA1	P38398-1.2	T248C	Neutral	0.044
BRCA1	P38398-1.2	T248D	Neutral	0.039
BRCA1	P38398-1.2	T248E	Neutral	0.053
BRCA1	P38398-1.2	T248F	Neutral	0.124
BRCA1	P38398-1.2	T248G	Neutral	0.135
BRCA1	P38398-1.2	T248H	Neutral	0.091
BRCA1	P38398-1.2	T248I	Neutral	0.072
BRCA1	P38398-1.2	T248K	Neutral	0.09
BRCA1	P38398-1.2	T248L	Neutral	0.072
BRCA1	P38398-1.2	T248M	Neutral	0.073
BRCA1	P38398-1.2	T248N	Neutral	0.028
BRCA1	P38398-1.2	T248P	Neutral	0.041
BRCA1	P38398-1.2	T248Q	Neutral	0.059
BRCA1	P38398-1.2	T248R	Neutral	0.117
BRCA1	P38398-1.2	T248S	Neutral	0.029
BRCA1	P38398-1.2	T248V	Neutral	0.034
BRCA1	P38398-1.2	T248W	Neutral	0.208
BRCA1	P38398-1.2	T248Y	Neutral	0.142
BRCA1	P38398-1.2	T249A	Neutral	0.023
BRCA1	P38398-1.2	T249C	Neutral	0.021
BRCA1	P38398-1.2	T249D	Neutral	0.019
BRCA1	P38398-1.2	T249E	Neutral	0.026
BRCA1	P38398-1.2	T249F	Neutral	0.062
BRCA1	P38398-1.2	T249G	Neutral	0.068
BRCA1	P38398-1.2	T249H	Neutral	0.045
BRCA1	P38398-1.2	T249I	Neutral	0.035
BRCA1	P38398-1.2	T249K	Neutral	0.044
BRCA1	P38398-1.2	T249L	Neutral	0.035
BRCA1	P38398-1.2	T249M	Neutral	0.035
BRCA1	P38398-1.2	T249N	Neutral	0.013
BRCA1	P38398-1.2	T249P	Neutral	0.019
BRCA1	P38398-1.2	T249Q	Neutral	0.029
BRCA1	P38398-1.2	T249R	Neutral	0.058
BRCA1	P38398-1.2	T249S	Neutral	0.014
BRCA1	P38398-1.2	T249V	Neutral	0.016
BRCA1	P38398-1.2	T249W	Neutral	0.109
BRCA1	P38398-1.2	T249Y	Neutral	0.072
BRCA1	P38398-1.2	E250A	Neutral	0.134
BRCA1	P38398-1.2	E250C	Neutral	0.23
BRCA1	P38398-1.2	E250D	Neutral	0.03
BRCA1	P38398-1.2	E250F	Neutral	0.179
BRCA1	P38398-1.2	E250G	Neutral	0.255
BRCA1	P38398-1.2	E250H	Neutral	0.049
BRCA1	P38398-1.2	E250I	Neutral	0.146
BRCA1	P38398-1.2	E250K	Neutral	0.05
BRCA1	P38398-1.2	E250L	Neutral	0.146
BRCA1	P38398-1.2	E250M	Neutral	0.107
BRCA1	P38398-1.2	E250N	Neutral	0.054
BRCA1	P38398-1.2	E250P	Neutral	0.084
BRCA1	P38398-1.2	E250Q	Neutral	0.023
BRCA1	P38398-1.2	E250R	Neutral	0.092
BRCA1	P38398-1.2	E250S	Neutral	0.086
BRCA1	P38398-1.2	E250T	Neutral	0.08
BRCA1	P38398-1.2	E250V	Neutral	0.086
BRCA1	P38398-1.2	E250W	Neutral	0.287
BRCA1	P38398-1.2	E250Y	Neutral	0.15
BRCA1	P38398-1.2	K251A	Neutral	0.322
BRCA1	P38398-1.2	K251C	Neutral	0.389
BRCA1	P38398-1.2	K251D	Neutral	0.221
BRCA1	P38398-1.2	K251E	Neutral	0.084
BRCA1	P38398-1.2	K251F	Neutral	0.174
BRCA1	P38398-1.2	K251G	Pathogenic	0.512
BRCA1	P38398-1.2	K251H	Neutral	0.133
BRCA1	P38398-1.2	K251I	Neutral	0.212
BRCA1	P38398-1.2	K251L	Neutral	0.158
BRCA1	P38398-1.2	K251M	Neutral	0.116
BRCA1	P38398-1.2	K251N	Neutral	0.15
BRCA1	P38398-1.2	K251P	Neutral	0.22
BRCA1	P38398-1.2	K251Q	Neutral	0.075
BRCA1	P38398-1.2	K251R	Neutral	0.046
BRCA1	P38398-1.2	K251S	Neutral	0.225
BRCA1	P38398-1.2	K251T	Neutral	0.21
BRCA1	P38398-1.2	K251V	Neutral	0.224
BRCA1	P38398-1.2	K251W	Neutral	0.28
BRCA1	P38398-1.2	K251Y	Neutral	0.145
BRCA1	P38398-1.2	R252A	Neutral	0.124
BRCA1	P38398-1.2	R252C	Neutral	0.16
BRCA1	P38398-1.2	R252D	Neutral	0.109
BRCA1	P38398-1.2	R252E	Neutral	0.038
BRCA1	P38398-1.2	R252F	Neutral	0.059
BRCA1	P38398-1.2	R252G	Neutral	0.238
BRCA1	P38398-1.2	R252H	Neutral	0.031
BRCA1	P38398-1.2	R252I	Neutral	0.074
BRCA1	P38398-1.2	R252K	Neutral	0.011
BRCA1	P38398-1.2	R252L	Neutral	0.053
BRCA1	P38398-1.2	R252M	Neutral	0.038
BRCA1	P38398-1.2	R252N	Neutral	0.05
BRCA1	P38398-1.2	R252P	Neutral	0.108
BRCA1	P38398-1.2	R252Q	Neutral	0.024
BRCA1	P38398-1.2	R252S	Neutral	0.111
BRCA1	P38398-1.2	R252T	Neutral	0.074
BRCA1	P38398-1.2	R252V	Neutral	0.11
BRCA1	P38398-1.2	R252W	Neutral	0.061
BRCA1	P38398-1.2	R252Y	Neutral	0.037
BRCA1	P38398-1.2	A253C	Neutral	0.394
BRCA1	P38398-1.2	A253D	Pathogenic	0.599
BRCA1	P38398-1.2	A253E	Pathogenic	0.608
BRCA1	P38398-1.2	A253F	Pathogenic	0.797
BRCA1	P38398-1.2	A253G	Neutral	0.396
BRCA1	P38398-1.2	A253H	Pathogenic	0.735
BRCA1	P38398-1.2	A253I	Pathogenic	0.682
BRCA1	P38398-1.2	A253K	Pathogenic	0.733
BRCA1	P38398-1.2	A253L	Pathogenic	0.682
BRCA1	P38398-1.2	A253M	Pathogenic	0.684
BRCA1	P38398-1.2	A253N	Pathogenic	0.626
BRCA1	P38398-1.2	A253P	Pathogenic	0.507
BRCA1	P38398-1.2	A253Q	Pathogenic	0.636
BRCA1	P38398-1.2	A253R	Pathogenic	0.786
BRCA1	P38398-1.2	A253S	Neutral	0.254
BRCA1	P38398-1.2	A253T	Neutral	0.435
BRCA1	P38398-1.2	A253V	Neutral	0.497
BRCA1	P38398-1.2	A253W	Pathogenic	0.913
BRCA1	P38398-1.2	A253Y	Pathogenic	0.82
BRCA1	P38398-1.2	A254C	Neutral	0.042
BRCA1	P38398-1.2	A254D	Neutral	0.091
BRCA1	P38398-1.2	A254E	Neutral	0.094
BRCA1	P38398-1.2	A254F	Neutral	0.208
BRCA1	P38398-1.2	A254G	Neutral	0.042
BRCA1	P38398-1.2	A254H	Neutral	0.156
BRCA1	P38398-1.2	A254I	Neutral	0.125
BRCA1	P38398-1.2	A254K	Neutral	0.155
BRCA1	P38398-1.2	A254L	Neutral	0.125
BRCA1	P38398-1.2	A254M	Neutral	0.126
BRCA1	P38398-1.2	A254N	Neutral	0.101
BRCA1	P38398-1.2	A254P	Neutral	0.064
BRCA1	P38398-1.2	A254Q	Neutral	0.105
BRCA1	P38398-1.2	A254R	Neutral	0.197
BRCA1	P38398-1.2	A254S	Neutral	0.022
BRCA1	P38398-1.2	A254T	Neutral	0.049
BRCA1	P38398-1.2	A254V	Neutral	0.062
BRCA1	P38398-1.2	A254W	Neutral	0.411
BRCA1	P38398-1.2	A254Y	Neutral	0.234
BRCA1	P38398-1.2	E255A	Neutral	0.372
BRCA1	P38398-1.2	E255C	Pathogenic	0.533
BRCA1	P38398-1.2	E255D	Neutral	0.106
BRCA1	P38398-1.2	E255F	Neutral	0.455
BRCA1	P38398-1.2	E255G	Pathogenic	0.567
BRCA1	P38398-1.2	E255H	Neutral	0.166
BRCA1	P38398-1.2	E255I	Neutral	0.395
BRCA1	P38398-1.2	E255K	Neutral	0.169
BRCA1	P38398-1.2	E255L	Neutral	0.396
BRCA1	P38398-1.2	E255M	Neutral	0.315
BRCA1	P38398-1.2	E255N	Neutral	0.18
BRCA1	P38398-1.2	E255P	Neutral	0.261
BRCA1	P38398-1.2	E255Q	Neutral	0.081
BRCA1	P38398-1.2	E255R	Neutral	0.28
BRCA1	P38398-1.2	E255S	Neutral	0.266
BRCA1	P38398-1.2	E255T	Neutral	0.25
BRCA1	P38398-1.2	E255V	Neutral	0.265
BRCA1	P38398-1.2	E255W	Pathogenic	0.607
BRCA1	P38398-1.2	E255Y	Neutral	0.403
BRCA1	P38398-1.2	R256A	Neutral	0.16
BRCA1	P38398-1.2	R256C	Neutral	0.203
BRCA1	P38398-1.2	R256D	Neutral	0.141
BRCA1	P38398-1.2	R256E	Neutral	0.05
BRCA1	P38398-1.2	R256F	Neutral	0.078
BRCA1	P38398-1.2	R256G	Neutral	0.296
BRCA1	P38398-1.2	R256H	Neutral	0.041
BRCA1	P38398-1.2	R256I	Neutral	0.097
BRCA1	P38398-1.2	R256K	Neutral	0.014
BRCA1	P38398-1.2	R256L	Neutral	0.07
BRCA1	P38398-1.2	R256M	Neutral	0.05
BRCA1	P38398-1.2	R256N	Neutral	0.066
BRCA1	P38398-1.2	R256P	Neutral	0.14
BRCA1	P38398-1.2	R256Q	Neutral	0.032
BRCA1	P38398-1.2	R256S	Neutral	0.143
BRCA1	P38398-1.2	R256T	Neutral	0.096
BRCA1	P38398-1.2	R256V	Neutral	0.143
BRCA1	P38398-1.2	R256W	Neutral	0.08
BRCA1	P38398-1.2	R256Y	Neutral	0.05
BRCA1	P38398-1.2	H257A	Pathogenic	0.566
BRCA1	P38398-1.2	H257C	Pathogenic	0.549
BRCA1	P38398-1.2	H257D	Neutral	0.344
BRCA1	P38398-1.2	H257E	Neutral	0.197
BRCA1	P38398-1.2	H257F	Neutral	0.293
BRCA1	P38398-1.2	H257G	Pathogenic	0.666
BRCA1	P38398-1.2	H257I	Neutral	0.402
BRCA1	P38398-1.2	H257K	Neutral	0.295
BRCA1	P38398-1.2	H257L	Neutral	0.402
BRCA1	P38398-1.2	H257M	Neutral	0.321
BRCA1	P38398-1.2	H257N	Neutral	0.185
BRCA1	P38398-1.2	H257P	Neutral	0.437
BRCA1	P38398-1.2	H257Q	Neutral	0.181
BRCA1	P38398-1.2	H257R	Neutral	0.28
BRCA1	P38398-1.2	H257S	Neutral	0.443
BRCA1	P38398-1.2	H257T	Neutral	0.423
BRCA1	P38398-1.2	H257V	Neutral	0.442
BRCA1	P38398-1.2	H257W	Pathogenic	0.524
BRCA1	P38398-1.2	H257Y	Neutral	0.139
BRCA1	P38398-1.2	P258A	Neutral	0.16
BRCA1	P38398-1.2	P258C	Neutral	0.206
BRCA1	P38398-1.2	P258D	Neutral	0.103
BRCA1	P38398-1.2	P258E	Neutral	0.146
BRCA1	P38398-1.2	P258F	Neutral	0.478
BRCA1	P38398-1.2	P258G	Neutral	0.294
BRCA1	P38398-1.2	P258H	Neutral	0.234
BRCA1	P38398-1.2	P258I	Neutral	0.333
BRCA1	P38398-1.2	P258K	Neutral	0.233
BRCA1	P38398-1.2	P258L	Neutral	0.333
BRCA1	P38398-1.2	P258M	Neutral	0.259
BRCA1	P38398-1.2	P258N	Neutral	0.156
BRCA1	P38398-1.2	P258Q	Neutral	0.162
BRCA1	P38398-1.2	P258R	Neutral	0.368
BRCA1	P38398-1.2	P258S	Neutral	0.142
BRCA1	P38398-1.2	P258T	Neutral	0.109
BRCA1	P38398-1.2	P258V	Neutral	0.187
BRCA1	P38398-1.2	P258W	Pathogenic	0.628
BRCA1	P38398-1.2	P258Y	Neutral	0.425
BRCA1	P38398-1.2	E259A	Pathogenic	0.637
BRCA1	P38398-1.2	E259C	Pathogenic	0.772
BRCA1	P38398-1.2	E259D	Neutral	0.26
BRCA1	P38398-1.2	E259F	Pathogenic	0.712
BRCA1	P38398-1.2	E259G	Pathogenic	0.795
BRCA1	P38398-1.2	E259H	Neutral	0.37
BRCA1	P38398-1.2	E259I	Pathogenic	0.66
BRCA1	P38398-1.2	E259K	Neutral	0.375
BRCA1	P38398-1.2	E259L	Pathogenic	0.66
BRCA1	P38398-1.2	E259M	Pathogenic	0.577
BRCA1	P38398-1.2	E259N	Neutral	0.395
BRCA1	P38398-1.2	E259P	Pathogenic	0.511
BRCA1	P38398-1.2	E259Q	Neutral	0.207
BRCA1	P38398-1.2	E259R	Pathogenic	0.536
BRCA1	P38398-1.2	E259S	Pathogenic	0.518
BRCA1	P38398-1.2	E259T	Neutral	0.496
BRCA1	P38398-1.2	E259V	Pathogenic	0.516
BRCA1	P38398-1.2	E259W	Pathogenic	0.82
BRCA1	P38398-1.2	E259Y	Pathogenic	0.666
BRCA1	P38398-1.2	K260A	Pathogenic	0.608
BRCA1	P38398-1.2	K260C	Pathogenic	0.676
BRCA1	P38398-1.2	K260D	Neutral	0.482
BRCA1	P38398-1.2	K260E	Neutral	0.231
BRCA1	P38398-1.2	K260F	Neutral	0.408
BRCA1	P38398-1.2	K260G	Pathogenic	0.774
BRCA1	P38398-1.2	K260H	Neutral	0.334
BRCA1	P38398-1.2	K260I	Neutral	0.468
BRCA1	P38398-1.2	K260L	Neutral	0.38
BRCA1	P38398-1.2	K260M	Neutral	0.301
BRCA1	P38398-1.2	K260N	Neutral	0.366
BRCA1	P38398-1.2	K260P	Neutral	0.48
BRCA1	P38398-1.2	K260Q	Neutral	0.211
BRCA1	P38398-1.2	K260R	Neutral	0.136
BRCA1	P38398-1.2	K260S	Neutral	0.487
BRCA1	P38398-1.2	K260T	Neutral	0.466
BRCA1	P38398-1.2	K260V	Neutral	0.486
BRCA1	P38398-1.2	K260W	Pathogenic	0.56
BRCA1	P38398-1.2	K260Y	Neutral	0.358
BRCA1	P38398-1.2	Y261A	Neutral	0.203
BRCA1	P38398-1.2	Y261C	Neutral	0.145
BRCA1	P38398-1.2	Y261D	Neutral	0.174
BRCA1	P38398-1.2	Y261E	Neutral	0.09
BRCA1	P38398-1.2	Y261F	Neutral	0.009
BRCA1	P38398-1.2	Y261G	Neutral	0.357
BRCA1	P38398-1.2	Y261H	Neutral	0.019
BRCA1	P38398-1.2	Y261I	Neutral	0.047
BRCA1	P38398-1.2	Y261K	Neutral	0.052
BRCA1	P38398-1.2	Y261L	Neutral	0.047
BRCA1	P38398-1.2	Y261M	Neutral	0.048
BRCA1	P38398-1.2	Y261N	Neutral	0.116
BRCA1	P38398-1.2	Y261P	Neutral	0.181
BRCA1	P38398-1.2	Y261Q	Neutral	0.058
BRCA1	P38398-1.2	Y261R	Neutral	0.053
BRCA1	P38398-1.2	Y261S	Neutral	0.181
BRCA1	P38398-1.2	Y261T	Neutral	0.125
BRCA1	P38398-1.2	Y261V	Neutral	0.071
BRCA1	P38398-1.2	Y261W	Neutral	0.018
BRCA1	P38398-1.2	Q262A	Pathogenic	0.551
BRCA1	P38398-1.2	Q262C	Pathogenic	0.622
BRCA1	P38398-1.2	Q262D	Neutral	0.333
BRCA1	P38398-1.2	Q262E	Neutral	0.14
BRCA1	P38398-1.2	Q262F	Pathogenic	0.581
BRCA1	P38398-1.2	Q262G	Pathogenic	0.73
BRCA1	P38398-1.2	Q262H	Neutral	0.248
BRCA1	P38398-1.2	Q262I	Pathogenic	0.52
BRCA1	P38398-1.2	Q262K	Neutral	0.249
BRCA1	P38398-1.2	Q262L	Neutral	0.43
BRCA1	P38398-1.2	Q262M	Neutral	0.269
BRCA1	P38398-1.2	Q262N	Neutral	0.31
BRCA1	P38398-1.2	Q262P	Neutral	0.422
BRCA1	P38398-1.2	Q262R	Neutral	0.306
BRCA1	P38398-1.2	Q262S	Neutral	0.429
BRCA1	P38398-1.2	Q262T	Neutral	0.408
BRCA1	P38398-1.2	Q262V	Neutral	0.427
BRCA1	P38398-1.2	Q262W	Pathogenic	0.64
BRCA1	P38398-1.2	Q262Y	Neutral	0.437
BRCA1	P38398-1.2	G263A	Neutral	0.15
BRCA1	P38398-1.2	G263C	Neutral	0.441
BRCA1	P38398-1.2	G263D	Neutral	0.3
BRCA1	P38398-1.2	G263E	Neutral	0.479
BRCA1	P38398-1.2	G263F	Pathogenic	0.698
BRCA1	P38398-1.2	G263H	Pathogenic	0.532
BRCA1	P38398-1.2	G263I	Pathogenic	0.722
BRCA1	P38398-1.2	G263K	Pathogenic	0.62
BRCA1	P38398-1.2	G263L	Pathogenic	0.723
BRCA1	P38398-1.2	G263M	Pathogenic	0.646
BRCA1	P38398-1.2	G263N	Neutral	0.25
BRCA1	P38398-1.2	G263P	Neutral	0.376
BRCA1	P38398-1.2	G263Q	Pathogenic	0.509
BRCA1	P38398-1.2	G263R	Pathogenic	0.685
BRCA1	P38398-1.2	G263S	Neutral	0.168
BRCA1	P38398-1.2	G263T	Neutral	0.394
BRCA1	P38398-1.2	G263V	Pathogenic	0.545
BRCA1	P38398-1.2	G263W	Pathogenic	0.748
BRCA1	P38398-1.2	G263Y	Pathogenic	0.728
BRCA1	P38398-1.2	S264A	Neutral	0.002
BRCA1	P38398-1.2	S264C	Neutral	0.005
BRCA1	P38398-1.2	S264D	Neutral	0.004
BRCA1	P38398-1.2	S264E	Neutral	0.006
BRCA1	P38398-1.2	S264F	Neutral	0.02
BRCA1	P38398-1.2	S264G	Neutral	0.004
BRCA1	P38398-1.2	S264H	Neutral	0.01
BRCA1	P38398-1.2	S264I	Neutral	0.016
BRCA1	P38398-1.2	S264K	Neutral	0.01
BRCA1	P38398-1.2	S264L	Neutral	0.016
BRCA1	P38398-1.2	S264M	Neutral	0.011
BRCA1	P38398-1.2	S264N	Neutral	0.003
BRCA1	P38398-1.2	S264P	Neutral	0.005
BRCA1	P38398-1.2	S264Q	Neutral	0.006
BRCA1	P38398-1.2	S264R	Neutral	0.019
BRCA1	P38398-1.2	S264T	Neutral	0.003
BRCA1	P38398-1.2	S264V	Neutral	0.011
BRCA1	P38398-1.2	S264W	Neutral	0.052
BRCA1	P38398-1.2	S264Y	Neutral	0.023
BRCA1	P38398-1.2	S265A	Neutral	0.034
BRCA1	P38398-1.2	S265C	Neutral	0.078
BRCA1	P38398-1.2	S265D	Neutral	0.062
BRCA1	P38398-1.2	S265E	Neutral	0.09
BRCA1	P38398-1.2	S265F	Neutral	0.262
BRCA1	P38398-1.2	S265G	Neutral	0.072
BRCA1	P38398-1.2	S265H	Neutral	0.149
BRCA1	P38398-1.2	S265I	Neutral	0.218
BRCA1	P38398-1.2	S265K	Neutral	0.149
BRCA1	P38398-1.2	S265L	Neutral	0.218
BRCA1	P38398-1.2	S265M	Neutral	0.164
BRCA1	P38398-1.2	S265N	Neutral	0.049
BRCA1	P38398-1.2	S265P	Neutral	0.085
BRCA1	P38398-1.2	S265Q	Neutral	0.1
BRCA1	P38398-1.2	S265R	Neutral	0.251
BRCA1	P38398-1.2	S265T	Neutral	0.046
BRCA1	P38398-1.2	S265V	Neutral	0.156
BRCA1	P38398-1.2	S265W	Neutral	0.486
BRCA1	P38398-1.2	S265Y	Neutral	0.292
BRCA1	P38398-1.2	V266A	Neutral	0.214
BRCA1	P38398-1.2	V266C	Neutral	0.207
BRCA1	P38398-1.2	V266D	Neutral	0.319
BRCA1	P38398-1.2	V266E	Neutral	0.207
BRCA1	P38398-1.2	V266F	Neutral	0.249
BRCA1	P38398-1.2	V266G	Pathogenic	0.552
BRCA1	P38398-1.2	V266H	Neutral	0.317
BRCA1	P38398-1.2	V266I	Neutral	0.057
BRCA1	P38398-1.2	V266K	Neutral	0.316
BRCA1	P38398-1.2	V266L	Neutral	0.111
BRCA1	P38398-1.2	V266M	Neutral	0.112
BRCA1	P38398-1.2	V266N	Neutral	0.296
BRCA1	P38398-1.2	V266P	Neutral	0.255
BRCA1	P38398-1.2	V266Q	Neutral	0.227
BRCA1	P38398-1.2	V266R	Neutral	0.47
BRCA1	P38398-1.2	V266S	Neutral	0.329
BRCA1	P38398-1.2	V266T	Neutral	0.133
BRCA1	P38398-1.2	V266W	Pathogenic	0.559
BRCA1	P38398-1.2	V266Y	Neutral	0.276
BRCA1	P38398-1.2	S267A	Neutral	0.081
BRCA1	P38398-1.2	S267C	Neutral	0.173
BRCA1	P38398-1.2	S267D	Neutral	0.141
BRCA1	P38398-1.2	S267E	Neutral	0.197
BRCA1	P38398-1.2	S267F	Neutral	0.469
BRCA1	P38398-1.2	S267G	Neutral	0.162
BRCA1	P38398-1.2	S267H	Neutral	0.303
BRCA1	P38398-1.2	S267I	Neutral	0.409
BRCA1	P38398-1.2	S267K	Neutral	0.302
BRCA1	P38398-1.2	S267L	Neutral	0.409
BRCA1	P38398-1.2	S267M	Neutral	0.327
BRCA1	P38398-1.2	S267N	Neutral	0.113
BRCA1	P38398-1.2	S267P	Neutral	0.187
BRCA1	P38398-1.2	S267Q	Neutral	0.216
BRCA1	P38398-1.2	S267R	Neutral	0.454
BRCA1	P38398-1.2	S267T	Neutral	0.107
BRCA1	P38398-1.2	S267V	Neutral	0.314
BRCA1	P38398-1.2	S267W	Pathogenic	0.701
BRCA1	P38398-1.2	S267Y	Pathogenic	0.506
BRCA1	P38398-1.2	N268A	Neutral	0.27
BRCA1	P38398-1.2	N268C	Neutral	0.256
BRCA1	P38398-1.2	N268D	Neutral	0.069
BRCA1	P38398-1.2	N268E	Neutral	0.113
BRCA1	P38398-1.2	N268F	Neutral	0.392
BRCA1	P38398-1.2	N268G	Neutral	0.215
BRCA1	P38398-1.2	N268H	Neutral	0.096
BRCA1	P38398-1.2	N268I	Neutral	0.336
BRCA1	P38398-1.2	N268K	Neutral	0.184
BRCA1	P38398-1.2	N268L	Neutral	0.336
BRCA1	P38398-1.2	N268M	Neutral	0.262
BRCA1	P38398-1.2	N268P	Neutral	0.18
BRCA1	P38398-1.2	N268Q	Neutral	0.124
BRCA1	P38398-1.2	N268R	Neutral	0.231
BRCA1	P38398-1.2	N268S	Neutral	0.099
BRCA1	P38398-1.2	N268T	Neutral	0.091
BRCA1	P38398-1.2	N268V	Neutral	0.251
BRCA1	P38398-1.2	N268W	Pathogenic	0.632
BRCA1	P38398-1.2	N268Y	Neutral	0.342
BRCA1	P38398-1.2	L269A	Neutral	0.428
BRCA1	P38398-1.2	L269C	Neutral	0.332
BRCA1	P38398-1.2	L269D	Pathogenic	0.562
BRCA1	P38398-1.2	L269E	Neutral	0.375
BRCA1	P38398-1.2	L269F	Neutral	0.161
BRCA1	P38398-1.2	L269G	Pathogenic	0.772
BRCA1	P38398-1.2	L269H	Neutral	0.332
BRCA1	P38398-1.2	L269I	Neutral	0.068
BRCA1	P38398-1.2	L269K	Neutral	0.275
BRCA1	P38398-1.2	L269M	Neutral	0.067
BRCA1	P38398-1.2	L269N	Neutral	0.445
BRCA1	P38398-1.2	L269P	Neutral	0.484
BRCA1	P38398-1.2	L269Q	Neutral	0.273
BRCA1	P38398-1.2	L269R	Neutral	0.336
BRCA1	P38398-1.2	L269S	Neutral	0.484
BRCA1	P38398-1.2	L269T	Neutral	0.296
BRCA1	P38398-1.2	L269V	Neutral	0.137
BRCA1	P38398-1.2	L269W	Neutral	0.423
BRCA1	P38398-1.2	L269Y	Neutral	0.238
BRCA1	P38398-1.2	H270A	Neutral	0.278
BRCA1	P38398-1.2	H270C	Neutral	0.264
BRCA1	P38398-1.2	H270D	Neutral	0.134
BRCA1	P38398-1.2	H270E	Neutral	0.067
BRCA1	P38398-1.2	H270F	Neutral	0.109
BRCA1	P38398-1.2	H270G	Neutral	0.37
BRCA1	P38398-1.2	H270I	Neutral	0.165
BRCA1	P38398-1.2	H270K	Neutral	0.11
BRCA1	P38398-1.2	H270L	Neutral	0.166
BRCA1	P38398-1.2	H270M	Neutral	0.122
BRCA1	P38398-1.2	H270N	Neutral	0.063
BRCA1	P38398-1.2	H270P	Neutral	0.186
BRCA1	P38398-1.2	H270Q	Neutral	0.061
BRCA1	P38398-1.2	H270R	Neutral	0.103
BRCA1	P38398-1.2	H270S	Neutral	0.19
BRCA1	P38398-1.2	H270T	Neutral	0.178
BRCA1	P38398-1.2	H270V	Neutral	0.19
BRCA1	P38398-1.2	H270W	Neutral	0.245
BRCA1	P38398-1.2	H270Y	Neutral	0.045
BRCA1	P38398-1.2	V271A	Neutral	0.427
BRCA1	P38398-1.2	V271C	Neutral	0.416
BRCA1	P38398-1.2	V271D	Pathogenic	0.56
BRCA1	P38398-1.2	V271E	Neutral	0.416
BRCA1	P38398-1.2	V271F	Neutral	0.474
BRCA1	P38398-1.2	V271G	Pathogenic	0.771
BRCA1	P38398-1.2	V271H	Pathogenic	0.559
BRCA1	P38398-1.2	V271I	Neutral	0.141
BRCA1	P38398-1.2	V271K	Pathogenic	0.557
BRCA1	P38398-1.2	V271L	Neutral	0.255
BRCA1	P38398-1.2	V271M	Neutral	0.257
BRCA1	P38398-1.2	V271N	Pathogenic	0.534
BRCA1	P38398-1.2	V271P	Neutral	0.482
BRCA1	P38398-1.2	V271Q	Neutral	0.445
BRCA1	P38398-1.2	V271R	Pathogenic	0.707
BRCA1	P38398-1.2	V271S	Pathogenic	0.573
BRCA1	P38398-1.2	V271T	Neutral	0.294
BRCA1	P38398-1.2	V271W	Pathogenic	0.775
BRCA1	P38398-1.2	V271Y	Pathogenic	0.509
BRCA1	P38398-1.2	E272A	Pathogenic	0.721
BRCA1	P38398-1.2	E272C	Pathogenic	0.833
BRCA1	P38398-1.2	E272D	Neutral	0.341
BRCA1	P38398-1.2	E272F	Pathogenic	0.785
BRCA1	P38398-1.2	E272G	Pathogenic	0.851
BRCA1	P38398-1.2	E272H	Neutral	0.464
BRCA1	P38398-1.2	E272I	Pathogenic	0.741
BRCA1	P38398-1.2	E272K	Neutral	0.469
BRCA1	P38398-1.2	E272L	Pathogenic	0.741
BRCA1	P38398-1.2	E272M	Pathogenic	0.667
BRCA1	P38398-1.2	E272N	Neutral	0.49
BRCA1	P38398-1.2	E272P	Pathogenic	0.606
BRCA1	P38398-1.2	E272Q	Neutral	0.278
BRCA1	P38398-1.2	E272R	Pathogenic	0.629
BRCA1	P38398-1.2	E272S	Pathogenic	0.613
BRCA1	P38398-1.2	E272T	Pathogenic	0.592
BRCA1	P38398-1.2	E272V	Pathogenic	0.611
BRCA1	P38398-1.2	E272W	Pathogenic	0.871
BRCA1	P38398-1.2	E272Y	Pathogenic	0.746
BRCA1	P38398-1.2	P273A	Pathogenic	0.79
BRCA1	P38398-1.2	P273C	Pathogenic	0.837
BRCA1	P38398-1.2	P273D	Pathogenic	0.694
BRCA1	P38398-1.2	P273E	Pathogenic	0.772
BRCA1	P38398-1.2	P273F	Pathogenic	0.948
BRCA1	P38398-1.2	P273G	Pathogenic	0.892
BRCA1	P38398-1.2	P273H	Pathogenic	0.858
BRCA1	P38398-1.2	P273I	Pathogenic	0.908
BRCA1	P38398-1.2	P273K	Pathogenic	0.857
BRCA1	P38398-1.2	P273L	Pathogenic	0.908
BRCA1	P38398-1.2	P273M	Pathogenic	0.874
BRCA1	P38398-1.2	P273N	Pathogenic	0.785
BRCA1	P38398-1.2	P273Q	Pathogenic	0.792
BRCA1	P38398-1.2	P273R	Pathogenic	0.92
BRCA1	P38398-1.2	P273S	Pathogenic	0.766
BRCA1	P38398-1.2	P273T	Pathogenic	0.707
BRCA1	P38398-1.2	P273V	Pathogenic	0.819
BRCA1	P38398-1.2	P273W	Pathogenic	0.971
BRCA1	P38398-1.2	P273Y	Pathogenic	0.936
BRCA1	P38398-1.2	C274A	Pathogenic	0.874
BRCA1	P38398-1.2	C274D	Pathogenic	0.937
BRCA1	P38398-1.2	C274E	Pathogenic	0.97
BRCA1	P38398-1.2	C274F	Pathogenic	0.965
BRCA1	P38398-1.2	C274G	Pathogenic	0.969
BRCA1	P38398-1.2	C274H	Pathogenic	0.965
BRCA1	P38398-1.2	C274I	Pathogenic	0.938
BRCA1	P38398-1.2	C274K	Pathogenic	0.975
BRCA1	P38398-1.2	C274L	Pathogenic	0.938
BRCA1	P38398-1.2	C274M	Pathogenic	0.939
BRCA1	P38398-1.2	C274N	Pathogenic	0.943
BRCA1	P38398-1.2	C274P	Pathogenic	0.937
BRCA1	P38398-1.2	C274Q	Pathogenic	0.961
BRCA1	P38398-1.2	C274R	Pathogenic	0.981
BRCA1	P38398-1.2	C274S	Pathogenic	0.896
BRCA1	P38398-1.2	C274T	Pathogenic	0.884
BRCA1	P38398-1.2	C274V	Pathogenic	0.909
BRCA1	P38398-1.2	C274W	Pathogenic	0.981
BRCA1	P38398-1.2	C274Y	Pathogenic	0.97
BRCA1	P38398-1.2	G275A	Pathogenic	0.885
BRCA1	P38398-1.2	G275C	Pathogenic	0.972
BRCA1	P38398-1.2	G275D	Pathogenic	0.949
BRCA1	P38398-1.2	G275E	Pathogenic	0.976
BRCA1	P38398-1.2	G275F	Pathogenic	0.99
BRCA1	P38398-1.2	G275H	Pathogenic	0.98
BRCA1	P38398-1.2	G275I	Pathogenic	0.991
BRCA1	P38398-1.2	G275K	Pathogenic	0.986
BRCA1	P38398-1.2	G275L	Pathogenic	0.991
BRCA1	P38398-1.2	G275M	Pathogenic	0.988
BRCA1	P38398-1.2	G275N	Pathogenic	0.936
BRCA1	P38398-1.2	G275P	Pathogenic	0.963
BRCA1	P38398-1.2	G275Q	Pathogenic	0.978
BRCA1	P38398-1.2	G275R	Pathogenic	0.99
BRCA1	P38398-1.2	G275S	Pathogenic	0.898
BRCA1	P38398-1.2	G275T	Pathogenic	0.966
BRCA1	P38398-1.2	G275V	Pathogenic	0.981
BRCA1	P38398-1.2	G275W	Pathogenic	0.992
BRCA1	P38398-1.2	G275Y	Pathogenic	0.992
BRCA1	P38398-1.2	T276A	Pathogenic	0.87
BRCA1	P38398-1.2	T276C	Pathogenic	0.862
BRCA1	P38398-1.2	T276D	Pathogenic	0.847
BRCA1	P38398-1.2	T276E	Pathogenic	0.883
BRCA1	P38398-1.2	T276F	Pathogenic	0.95
BRCA1	P38398-1.2	T276G	Pathogenic	0.955
BRCA1	P38398-1.2	T276H	Pathogenic	0.931
BRCA1	P38398-1.2	T276I	Pathogenic	0.913
BRCA1	P38398-1.2	T276K	Pathogenic	0.931
BRCA1	P38398-1.2	T276L	Pathogenic	0.913
BRCA1	P38398-1.2	T276M	Pathogenic	0.913
BRCA1	P38398-1.2	T276N	Pathogenic	0.798
BRCA1	P38398-1.2	T276P	Pathogenic	0.851
BRCA1	P38398-1.2	T276Q	Pathogenic	0.895
BRCA1	P38398-1.2	T276R	Pathogenic	0.947
BRCA1	P38398-1.2	T276S	Pathogenic	0.802
BRCA1	P38398-1.2	T276V	Pathogenic	0.828
BRCA1	P38398-1.2	T276W	Pathogenic	0.973
BRCA1	P38398-1.2	T276Y	Pathogenic	0.957
BRCA1	P38398-1.2	N277A	Neutral	0.062
BRCA1	P38398-1.2	N277C	Neutral	0.058
BRCA1	P38398-1.2	N277D	Neutral	0.013
BRCA1	P38398-1.2	N277E	Neutral	0.022
BRCA1	P38398-1.2	N277F	Neutral	0.104
BRCA1	P38398-1.2	N277G	Neutral	0.047
BRCA1	P38398-1.2	N277H	Neutral	0.019
BRCA1	P38398-1.2	N277I	Neutral	0.083
BRCA1	P38398-1.2	N277K	Neutral	0.039
BRCA1	P38398-1.2	N277L	Neutral	0.083
BRCA1	P38398-1.2	N277M	Neutral	0.06
BRCA1	P38398-1.2	N277P	Neutral	0.038
BRCA1	P38398-1.2	N277Q	Neutral	0.025
BRCA1	P38398-1.2	N277R	Neutral	0.051
BRCA1	P38398-1.2	N277S	Neutral	0.019
BRCA1	P38398-1.2	N277T	Neutral	0.018
BRCA1	P38398-1.2	N277V	Neutral	0.057
BRCA1	P38398-1.2	N277W	Neutral	0.235
BRCA1	P38398-1.2	N277Y	Neutral	0.085
BRCA1	P38398-1.2	T278A	Neutral	0.433
BRCA1	P38398-1.2	T278C	Neutral	0.416
BRCA1	P38398-1.2	T278D	Neutral	0.388
BRCA1	P38398-1.2	T278E	Neutral	0.464
BRCA1	P38398-1.2	T278F	Pathogenic	0.687
BRCA1	P38398-1.2	T278G	Pathogenic	0.706
BRCA1	P38398-1.2	T278H	Pathogenic	0.607
BRCA1	P38398-1.2	T278I	Pathogenic	0.544
BRCA1	P38398-1.2	T278K	Pathogenic	0.605
BRCA1	P38398-1.2	T278L	Pathogenic	0.545
BRCA1	P38398-1.2	T278M	Pathogenic	0.547
BRCA1	P38398-1.2	T278N	Neutral	0.311
BRCA1	P38398-1.2	T278P	Neutral	0.396
BRCA1	P38398-1.2	T278Q	Neutral	0.494
BRCA1	P38398-1.2	T278R	Pathogenic	0.672
BRCA1	P38398-1.2	T278S	Neutral	0.316
BRCA1	P38398-1.2	T278V	Neutral	0.355
BRCA1	P38398-1.2	T278W	Pathogenic	0.802
BRCA1	P38398-1.2	T278Y	Pathogenic	0.718
BRCA1	P38398-1.2	H279A	Pathogenic	0.853
BRCA1	P38398-1.2	H279C	Pathogenic	0.844
BRCA1	P38398-1.2	H279D	Pathogenic	0.7
BRCA1	P38398-1.2	H279E	Pathogenic	0.521
BRCA1	P38398-1.2	H279F	Pathogenic	0.648
BRCA1	P38398-1.2	H279G	Pathogenic	0.898
BRCA1	P38398-1.2	H279I	Pathogenic	0.749
BRCA1	P38398-1.2	H279K	Pathogenic	0.65
BRCA1	P38398-1.2	H279L	Pathogenic	0.749
BRCA1	P38398-1.2	H279M	Pathogenic	0.677
BRCA1	P38398-1.2	H279N	Pathogenic	0.502
BRCA1	P38398-1.2	H279P	Pathogenic	0.775
BRCA1	P38398-1.2	H279Q	Neutral	0.495
BRCA1	P38398-1.2	H279R	Pathogenic	0.633
BRCA1	P38398-1.2	H279S	Pathogenic	0.779
BRCA1	P38398-1.2	H279T	Pathogenic	0.765
BRCA1	P38398-1.2	H279V	Pathogenic	0.779
BRCA1	P38398-1.2	H279W	Pathogenic	0.83
BRCA1	P38398-1.2	H279Y	Neutral	0.417
BRCA1	P38398-1.2	A280C	Pathogenic	0.965
BRCA1	P38398-1.2	A280D	Pathogenic	0.985
BRCA1	P38398-1.2	A280E	Pathogenic	0.985
BRCA1	P38398-1.2	A280F	Pathogenic	0.994
BRCA1	P38398-1.2	A280G	Pathogenic	0.966
BRCA1	P38398-1.2	A280H	Pathogenic	0.992
BRCA1	P38398-1.2	A280I	Pathogenic	0.989
BRCA1	P38398-1.2	A280K	Pathogenic	0.992
BRCA1	P38398-1.2	A280L	Pathogenic	0.989
BRCA1	P38398-1.2	A280M	Pathogenic	0.989
BRCA1	P38398-1.2	A280N	Pathogenic	0.986
BRCA1	P38398-1.2	A280P	Pathogenic	0.978
BRCA1	P38398-1.2	A280Q	Pathogenic	0.987
BRCA1	P38398-1.2	A280R	Pathogenic	0.994
BRCA1	P38398-1.2	A280S	Pathogenic	0.936
BRCA1	P38398-1.2	A280T	Pathogenic	0.971
BRCA1	P38398-1.2	A280V	Pathogenic	0.977
BRCA1	P38398-1.2	A280W	Pathogenic	0.998
BRCA1	P38398-1.2	A280Y	Pathogenic	0.995
BRCA1	P38398-1.2	S281A	Pathogenic	0.619
BRCA1	P38398-1.2	S281C	Pathogenic	0.795
BRCA1	P38398-1.2	S281D	Pathogenic	0.752
BRCA1	P38398-1.2	S281E	Pathogenic	0.819
BRCA1	P38398-1.2	S281F	Pathogenic	0.942
BRCA1	P38398-1.2	S281G	Pathogenic	0.782
BRCA1	P38398-1.2	S281H	Pathogenic	0.889
BRCA1	P38398-1.2	S281I	Pathogenic	0.928
BRCA1	P38398-1.2	S281K	Pathogenic	0.889
BRCA1	P38398-1.2	S281L	Pathogenic	0.928
BRCA1	P38398-1.2	S281M	Pathogenic	0.9
BRCA1	P38398-1.2	S281N	Pathogenic	0.703
BRCA1	P38398-1.2	S281P	Pathogenic	0.81
BRCA1	P38398-1.2	S281Q	Pathogenic	0.836
BRCA1	P38398-1.2	S281R	Pathogenic	0.939
BRCA1	P38398-1.2	S281T	Pathogenic	0.69
BRCA1	P38398-1.2	S281V	Pathogenic	0.895
BRCA1	P38398-1.2	S281W	Pathogenic	0.977
BRCA1	P38398-1.2	S281Y	Pathogenic	0.95
BRCA1	P38398-1.2	S282A	Pathogenic	0.83
BRCA1	P38398-1.2	S282C	Pathogenic	0.921
BRCA1	P38398-1.2	S282D	Pathogenic	0.901
BRCA1	P38398-1.2	S282E	Pathogenic	0.932
BRCA1	P38398-1.2	S282F	Pathogenic	0.98
BRCA1	P38398-1.2	S282G	Pathogenic	0.915
BRCA1	P38398-1.2	S282H	Pathogenic	0.96
BRCA1	P38398-1.2	S282I	Pathogenic	0.975
BRCA1	P38398-1.2	S282K	Pathogenic	0.96
BRCA1	P38398-1.2	S282L	Pathogenic	0.975
BRCA1	P38398-1.2	S282M	Pathogenic	0.964
BRCA1	P38398-1.2	S282N	Pathogenic	0.877
BRCA1	P38398-1.2	S282P	Pathogenic	0.928
BRCA1	P38398-1.2	S282Q	Pathogenic	0.939
BRCA1	P38398-1.2	S282R	Pathogenic	0.979
BRCA1	P38398-1.2	S282T	Pathogenic	0.87
BRCA1	P38398-1.2	S282V	Pathogenic	0.962
BRCA1	P38398-1.2	S282W	Pathogenic	0.992
BRCA1	P38398-1.2	S282Y	Pathogenic	0.983
BRCA1	P38398-1.2	L283A	Pathogenic	0.981
BRCA1	P38398-1.2	L283C	Pathogenic	0.971
BRCA1	P38398-1.2	L283D	Pathogenic	0.989
BRCA1	P38398-1.2	L283E	Pathogenic	0.976
BRCA1	P38398-1.2	L283F	Pathogenic	0.928
BRCA1	P38398-1.2	L283G	Pathogenic	0.996
BRCA1	P38398-1.2	L283H	Pathogenic	0.971
BRCA1	P38398-1.2	L283I	Pathogenic	0.83
BRCA1	P38398-1.2	L283K	Pathogenic	0.962
BRCA1	P38398-1.2	L283M	Pathogenic	0.829
BRCA1	P38398-1.2	L283N	Pathogenic	0.982
BRCA1	P38398-1.2	L283P	Pathogenic	0.984
BRCA1	P38398-1.2	L283Q	Pathogenic	0.962
BRCA1	P38398-1.2	L283R	Pathogenic	0.971
BRCA1	P38398-1.2	L283S	Pathogenic	0.984
BRCA1	P38398-1.2	L283T	Pathogenic	0.966
BRCA1	P38398-1.2	L283V	Pathogenic	0.914
BRCA1	P38398-1.2	L283W	Pathogenic	0.98
BRCA1	P38398-1.2	L283Y	Pathogenic	0.954
BRCA1	P38398-1.2	Q284A	Pathogenic	0.91
BRCA1	P38398-1.2	Q284C	Pathogenic	0.931
BRCA1	P38398-1.2	Q284D	Pathogenic	0.805
BRCA1	P38398-1.2	Q284E	Pathogenic	0.572
BRCA1	P38398-1.2	Q284F	Pathogenic	0.919
BRCA1	P38398-1.2	Q284G	Pathogenic	0.957
BRCA1	P38398-1.2	Q284H	Pathogenic	0.731
BRCA1	P38398-1.2	Q284I	Pathogenic	0.899
BRCA1	P38398-1.2	Q284K	Pathogenic	0.732
BRCA1	P38398-1.2	Q284L	Pathogenic	0.862
BRCA1	P38398-1.2	Q284M	Pathogenic	0.752
BRCA1	P38398-1.2	Q284N	Pathogenic	0.787
BRCA1	P38398-1.2	Q284P	Pathogenic	0.857
BRCA1	P38398-1.2	Q284R	Pathogenic	0.784
BRCA1	P38398-1.2	Q284S	Pathogenic	0.861
BRCA1	P38398-1.2	Q284T	Pathogenic	0.85
BRCA1	P38398-1.2	Q284V	Pathogenic	0.86
BRCA1	P38398-1.2	Q284W	Pathogenic	0.936
BRCA1	P38398-1.2	Q284Y	Pathogenic	0.865
BRCA1	P38398-1.2	H285A	Pathogenic	0.609
BRCA1	P38398-1.2	H285C	Pathogenic	0.592
BRCA1	P38398-1.2	H285D	Neutral	0.385
BRCA1	P38398-1.2	H285E	Neutral	0.226
BRCA1	P38398-1.2	H285F	Neutral	0.331
BRCA1	P38398-1.2	H285G	Pathogenic	0.704
BRCA1	P38398-1.2	H285I	Neutral	0.445
BRCA1	P38398-1.2	H285K	Neutral	0.333
BRCA1	P38398-1.2	H285L	Neutral	0.446
BRCA1	P38398-1.2	H285M	Neutral	0.361
BRCA1	P38398-1.2	H285N	Neutral	0.214
BRCA1	P38398-1.2	H285P	Neutral	0.481
BRCA1	P38398-1.2	H285Q	Neutral	0.209
BRCA1	P38398-1.2	H285R	Neutral	0.317
BRCA1	P38398-1.2	H285S	Neutral	0.487
BRCA1	P38398-1.2	H285T	Neutral	0.467
BRCA1	P38398-1.2	H285V	Neutral	0.487
BRCA1	P38398-1.2	H285W	Pathogenic	0.568
BRCA1	P38398-1.2	H285Y	Neutral	0.162
BRCA1	P38398-1.2	E286A	Pathogenic	0.738
BRCA1	P38398-1.2	E286C	Pathogenic	0.845
BRCA1	P38398-1.2	E286D	Neutral	0.361
BRCA1	P38398-1.2	E286F	Pathogenic	0.799
BRCA1	P38398-1.2	E286G	Pathogenic	0.862
BRCA1	P38398-1.2	E286H	Neutral	0.486
BRCA1	P38398-1.2	E286I	Pathogenic	0.757
BRCA1	P38398-1.2	E286K	Neutral	0.491
BRCA1	P38398-1.2	E286L	Pathogenic	0.757
BRCA1	P38398-1.2	E286M	Pathogenic	0.686
BRCA1	P38398-1.2	E286N	Pathogenic	0.511
BRCA1	P38398-1.2	E286P	Pathogenic	0.627
BRCA1	P38398-1.2	E286Q	Neutral	0.296
BRCA1	P38398-1.2	E286R	Pathogenic	0.65
BRCA1	P38398-1.2	E286S	Pathogenic	0.633
BRCA1	P38398-1.2	E286T	Pathogenic	0.613
BRCA1	P38398-1.2	E286V	Pathogenic	0.632
BRCA1	P38398-1.2	E286W	Pathogenic	0.88
BRCA1	P38398-1.2	E286Y	Pathogenic	0.762
BRCA1	P38398-1.2	N287A	Pathogenic	0.791
BRCA1	P38398-1.2	N287C	Pathogenic	0.779
BRCA1	P38398-1.2	N287D	Neutral	0.43
BRCA1	P38398-1.2	N287E	Pathogenic	0.565
BRCA1	P38398-1.2	N287F	Pathogenic	0.868
BRCA1	P38398-1.2	N287G	Pathogenic	0.737
BRCA1	P38398-1.2	N287H	Pathogenic	0.521
BRCA1	P38398-1.2	N287I	Pathogenic	0.838
BRCA1	P38398-1.2	N287K	Pathogenic	0.697
BRCA1	P38398-1.2	N287L	Pathogenic	0.838
BRCA1	P38398-1.2	N287M	Pathogenic	0.784
BRCA1	P38398-1.2	N287P	Pathogenic	0.692
BRCA1	P38398-1.2	N287Q	Pathogenic	0.591
BRCA1	P38398-1.2	N287R	Pathogenic	0.754
BRCA1	P38398-1.2	N287S	Pathogenic	0.527
BRCA1	P38398-1.2	N287T	Pathogenic	0.506
BRCA1	P38398-1.2	N287V	Pathogenic	0.774
BRCA1	P38398-1.2	N287W	Pathogenic	0.946
BRCA1	P38398-1.2	N287Y	Pathogenic	0.842
BRCA1	P38398-1.2	S288A	Neutral	0.302
BRCA1	P38398-1.2	S288C	Pathogenic	0.508
BRCA1	P38398-1.2	S288D	Neutral	0.447
BRCA1	P38398-1.2	S288E	Pathogenic	0.547
BRCA1	P38398-1.2	S288F	Pathogenic	0.813
BRCA1	P38398-1.2	S288G	Neutral	0.489
BRCA1	P38398-1.2	S288H	Pathogenic	0.682
BRCA1	P38398-1.2	S288I	Pathogenic	0.773
BRCA1	P38398-1.2	S288K	Pathogenic	0.681
BRCA1	P38398-1.2	S288L	Pathogenic	0.773
BRCA1	P38398-1.2	S288M	Pathogenic	0.705
BRCA1	P38398-1.2	S288N	Neutral	0.386
BRCA1	P38398-1.2	S288P	Pathogenic	0.532
BRCA1	P38398-1.2	S288Q	Pathogenic	0.576
BRCA1	P38398-1.2	S288R	Pathogenic	0.804
BRCA1	P38398-1.2	S288T	Neutral	0.372
BRCA1	P38398-1.2	S288V	Pathogenic	0.693
BRCA1	P38398-1.2	S288W	Pathogenic	0.92
BRCA1	P38398-1.2	S288Y	Pathogenic	0.835
BRCA1	P38398-1.2	S289A	Neutral	0.224
BRCA1	P38398-1.2	S289C	Neutral	0.408
BRCA1	P38398-1.2	S289D	Neutral	0.35
BRCA1	P38398-1.2	S289E	Neutral	0.446
BRCA1	P38398-1.2	S289F	Pathogenic	0.744
BRCA1	P38398-1.2	S289G	Neutral	0.389
BRCA1	P38398-1.2	S289H	Pathogenic	0.588
BRCA1	P38398-1.2	S289I	Pathogenic	0.694
BRCA1	P38398-1.2	S289K	Pathogenic	0.588
BRCA1	P38398-1.2	S289L	Pathogenic	0.695
BRCA1	P38398-1.2	S289M	Pathogenic	0.615
BRCA1	P38398-1.2	S289N	Neutral	0.296
BRCA1	P38398-1.2	S289P	Neutral	0.431
BRCA1	P38398-1.2	S289Q	Neutral	0.476
BRCA1	P38398-1.2	S289R	Pathogenic	0.732
BRCA1	P38398-1.2	S289T	Neutral	0.283
BRCA1	P38398-1.2	S289V	Pathogenic	0.601
BRCA1	P38398-1.2	S289W	Pathogenic	0.885
BRCA1	P38398-1.2	S289Y	Pathogenic	0.771
BRCA1	P38398-1.2	L290A	Pathogenic	0.952
BRCA1	P38398-1.2	L290C	Pathogenic	0.929
BRCA1	P38398-1.2	L290D	Pathogenic	0.971
BRCA1	P38398-1.2	L290E	Pathogenic	0.941
BRCA1	P38398-1.2	L290F	Pathogenic	0.836
BRCA1	P38398-1.2	L290G	Pathogenic	0.989
BRCA1	P38398-1.2	L290H	Pathogenic	0.93
BRCA1	P38398-1.2	L290I	Pathogenic	0.658
BRCA1	P38398-1.2	L290K	Pathogenic	0.909
BRCA1	P38398-1.2	L290M	Pathogenic	0.656
BRCA1	P38398-1.2	L290N	Pathogenic	0.955
BRCA1	P38398-1.2	L290P	Pathogenic	0.961
BRCA1	P38398-1.2	L290Q	Pathogenic	0.909
BRCA1	P38398-1.2	L290R	Pathogenic	0.93
BRCA1	P38398-1.2	L290S	Pathogenic	0.961
BRCA1	P38398-1.2	L290T	Pathogenic	0.918
BRCA1	P38398-1.2	L290V	Pathogenic	0.807
BRCA1	P38398-1.2	L290W	Pathogenic	0.951
BRCA1	P38398-1.2	L290Y	Pathogenic	0.892
BRCA1	P38398-1.2	L291A	Pathogenic	0.988
BRCA1	P38398-1.2	L291C	Pathogenic	0.982
BRCA1	P38398-1.2	L291D	Pathogenic	0.993
BRCA1	P38398-1.2	L291E	Pathogenic	0.985
BRCA1	P38398-1.2	L291F	Pathogenic	0.955
BRCA1	P38398-1.2	L291G	Pathogenic	0.997
BRCA1	P38398-1.2	L291H	Pathogenic	0.982
BRCA1	P38398-1.2	L291I	Pathogenic	0.889
BRCA1	P38398-1.2	L291K	Pathogenic	0.977
BRCA1	P38398-1.2	L291M	Pathogenic	0.888
BRCA1	P38398-1.2	L291N	Pathogenic	0.989
BRCA1	P38398-1.2	L291P	Pathogenic	0.99
BRCA1	P38398-1.2	L291Q	Pathogenic	0.976
BRCA1	P38398-1.2	L291R	Pathogenic	0.982
BRCA1	P38398-1.2	L291S	Pathogenic	0.99
BRCA1	P38398-1.2	L291T	Pathogenic	0.979
BRCA1	P38398-1.2	L291V	Pathogenic	0.946
BRCA1	P38398-1.2	L291W	Pathogenic	0.988
BRCA1	P38398-1.2	L291Y	Pathogenic	0.972
BRCA1	P38398-1.2	L292A	Pathogenic	0.748
BRCA1	P38398-1.2	L292C	Pathogenic	0.664
BRCA1	P38398-1.2	L292D	Pathogenic	0.836
BRCA1	P38398-1.2	L292E	Pathogenic	0.704
BRCA1	P38398-1.2	L292F	Neutral	0.432
BRCA1	P38398-1.2	L292G	Pathogenic	0.931
BRCA1	P38398-1.2	L292H	Pathogenic	0.664
BRCA1	P38398-1.2	L292I	Neutral	0.224
BRCA1	P38398-1.2	L292K	Pathogenic	0.6
BRCA1	P38398-1.2	L292M	Neutral	0.222
BRCA1	P38398-1.2	L292N	Pathogenic	0.76
BRCA1	P38398-1.2	L292P	Pathogenic	0.788
BRCA1	P38398-1.2	L292Q	Pathogenic	0.598
BRCA1	P38398-1.2	L292R	Pathogenic	0.667
BRCA1	P38398-1.2	L292S	Pathogenic	0.788
BRCA1	P38398-1.2	L292T	Pathogenic	0.625
BRCA1	P38398-1.2	L292V	Neutral	0.386
BRCA1	P38398-1.2	L292W	Pathogenic	0.744
BRCA1	P38398-1.2	L292Y	Pathogenic	0.553
BRCA1	P38398-1.2	T293A	Pathogenic	0.837
BRCA1	P38398-1.2	T293C	Pathogenic	0.827
BRCA1	P38398-1.2	T293D	Pathogenic	0.809
BRCA1	P38398-1.2	T293E	Pathogenic	0.853
BRCA1	P38398-1.2	T293F	Pathogenic	0.936
BRCA1	P38398-1.2	T293G	Pathogenic	0.942
BRCA1	P38398-1.2	T293H	Pathogenic	0.912
BRCA1	P38398-1.2	T293I	Pathogenic	0.889
BRCA1	P38398-1.2	T293K	Pathogenic	0.911
BRCA1	P38398-1.2	T293L	Pathogenic	0.889
BRCA1	P38398-1.2	T293M	Pathogenic	0.89
BRCA1	P38398-1.2	T293N	Pathogenic	0.751
BRCA1	P38398-1.2	T293P	Pathogenic	0.814
BRCA1	P38398-1.2	T293Q	Pathogenic	0.867
BRCA1	P38398-1.2	T293R	Pathogenic	0.932
BRCA1	P38398-1.2	T293S	Pathogenic	0.756
BRCA1	P38398-1.2	T293V	Pathogenic	0.787
BRCA1	P38398-1.2	T293W	Pathogenic	0.964
BRCA1	P38398-1.2	T293Y	Pathogenic	0.945
BRCA1	P38398-1.2	K294A	Pathogenic	0.56
BRCA1	P38398-1.2	K294C	Pathogenic	0.631
BRCA1	P38398-1.2	K294D	Neutral	0.433
BRCA1	P38398-1.2	K294E	Neutral	0.198
BRCA1	P38398-1.2	K294F	Neutral	0.362
BRCA1	P38398-1.2	K294G	Pathogenic	0.738
BRCA1	P38398-1.2	K294H	Neutral	0.292
BRCA1	P38398-1.2	K294I	Neutral	0.42
BRCA1	P38398-1.2	K294L	Neutral	0.335
BRCA1	P38398-1.2	K294M	Neutral	0.261
BRCA1	P38398-1.2	K294N	Neutral	0.321
BRCA1	P38398-1.2	K294P	Neutral	0.432
BRCA1	P38398-1.2	K294Q	Neutral	0.18
BRCA1	P38398-1.2	K294R	Neutral	0.114
BRCA1	P38398-1.2	K294S	Neutral	0.438
BRCA1	P38398-1.2	K294T	Neutral	0.417
BRCA1	P38398-1.2	K294V	Neutral	0.437
BRCA1	P38398-1.2	K294W	Pathogenic	0.511
BRCA1	P38398-1.2	K294Y	Neutral	0.314
BRCA1	P38398-1.2	D295A	Pathogenic	0.861
BRCA1	P38398-1.2	D295C	Pathogenic	0.852
BRCA1	P38398-1.2	D295E	Pathogenic	0.563
BRCA1	P38398-1.2	D295F	Pathogenic	0.931
BRCA1	P38398-1.2	D295G	Pathogenic	0.868
BRCA1	P38398-1.2	D295H	Pathogenic	0.822
BRCA1	P38398-1.2	D295I	Pathogenic	0.914
BRCA1	P38398-1.2	D295K	Pathogenic	0.872
BRCA1	P38398-1.2	D295L	Pathogenic	0.938
BRCA1	P38398-1.2	D295M	Pathogenic	0.914
BRCA1	P38398-1.2	D295N	Pathogenic	0.581
BRCA1	P38398-1.2	D295P	Pathogenic	0.719
BRCA1	P38398-1.2	D295Q	Pathogenic	0.747
BRCA1	P38398-1.2	D295R	Pathogenic	0.929
BRCA1	P38398-1.2	D295S	Pathogenic	0.725
BRCA1	P38398-1.2	D295T	Pathogenic	0.725
BRCA1	P38398-1.2	D295V	Pathogenic	0.875
BRCA1	P38398-1.2	D295W	Pathogenic	0.973
BRCA1	P38398-1.2	D295Y	Pathogenic	0.94
BRCA1	P38398-1.2	R296A	Pathogenic	0.926
BRCA1	P38398-1.2	R296C	Pathogenic	0.944
BRCA1	P38398-1.2	R296D	Pathogenic	0.915
BRCA1	P38398-1.2	R296E	Pathogenic	0.777
BRCA1	P38398-1.2	R296F	Pathogenic	0.848
BRCA1	P38398-1.2	R296G	Pathogenic	0.965
BRCA1	P38398-1.2	R296H	Pathogenic	0.737
BRCA1	P38398-1.2	R296I	Pathogenic	0.876
BRCA1	P38398-1.2	R296K	Neutral	0.487
BRCA1	P38398-1.2	R296L	Pathogenic	0.832
BRCA1	P38398-1.2	R296M	Pathogenic	0.776
BRCA1	P38398-1.2	R296N	Pathogenic	0.823
BRCA1	P38398-1.2	R296P	Pathogenic	0.915
BRCA1	P38398-1.2	R296Q	Pathogenic	0.682
BRCA1	P38398-1.2	R296S	Pathogenic	0.917
BRCA1	P38398-1.2	R296T	Pathogenic	0.875
BRCA1	P38398-1.2	R296V	Pathogenic	0.916
BRCA1	P38398-1.2	R296W	Pathogenic	0.852
BRCA1	P38398-1.2	R296Y	Pathogenic	0.775
BRCA1	P38398-1.2	M297A	Pathogenic	0.846
BRCA1	P38398-1.2	M297C	Pathogenic	0.785
BRCA1	P38398-1.2	M297D	Pathogenic	0.868
BRCA1	P38398-1.2	M297E	Pathogenic	0.754
BRCA1	P38398-1.2	M297F	Pathogenic	0.581
BRCA1	P38398-1.2	M297G	Pathogenic	0.945
BRCA1	P38398-1.2	M297H	Pathogenic	0.718
BRCA1	P38398-1.2	M297I	Neutral	0.43
BRCA1	P38398-1.2	M297K	Pathogenic	0.659
BRCA1	P38398-1.2	M297L	Neutral	0.345
BRCA1	P38398-1.2	M297N	Pathogenic	0.804
BRCA1	P38398-1.2	M297P	Pathogenic	0.827
BRCA1	P38398-1.2	M297Q	Pathogenic	0.572
BRCA1	P38398-1.2	M297R	Pathogenic	0.721
BRCA1	P38398-1.2	M297S	Pathogenic	0.827
BRCA1	P38398-1.2	M297T	Pathogenic	0.756
BRCA1	P38398-1.2	M297V	Pathogenic	0.538
BRCA1	P38398-1.2	M297W	Pathogenic	0.787
BRCA1	P38398-1.2	M297Y	Pathogenic	0.697
BRCA1	P38398-1.2	N298A	Pathogenic	0.545
BRCA1	P38398-1.2	N298C	Pathogenic	0.527
BRCA1	P38398-1.2	N298D	Neutral	0.193
BRCA1	P38398-1.2	N298E	Neutral	0.292
BRCA1	P38398-1.2	N298F	Pathogenic	0.676
BRCA1	P38398-1.2	N298G	Neutral	0.47
BRCA1	P38398-1.2	N298H	Neutral	0.256
BRCA1	P38398-1.2	N298I	Pathogenic	0.62
BRCA1	P38398-1.2	N298K	Neutral	0.421
BRCA1	P38398-1.2	N298L	Pathogenic	0.621
BRCA1	P38398-1.2	N298M	Pathogenic	0.535
BRCA1	P38398-1.2	N298P	Neutral	0.416
BRCA1	P38398-1.2	N298Q	Neutral	0.314
BRCA1	P38398-1.2	N298R	Neutral	0.493
BRCA1	P38398-1.2	N298S	Neutral	0.261
BRCA1	P38398-1.2	N298T	Neutral	0.245
BRCA1	P38398-1.2	N298V	Pathogenic	0.52
BRCA1	P38398-1.2	N298W	Pathogenic	0.847
BRCA1	P38398-1.2	N298Y	Pathogenic	0.627
BRCA1	P38398-1.2	V299A	Pathogenic	0.829
BRCA1	P38398-1.2	V299C	Pathogenic	0.823
BRCA1	P38398-1.2	V299D	Pathogenic	0.893
BRCA1	P38398-1.2	V299E	Pathogenic	0.823
BRCA1	P38398-1.2	V299F	Pathogenic	0.855
BRCA1	P38398-1.2	V299G	Pathogenic	0.956
BRCA1	P38398-1.2	V299H	Pathogenic	0.892
BRCA1	P38398-1.2	V299I	Pathogenic	0.518
BRCA1	P38398-1.2	V299K	Pathogenic	0.892
BRCA1	P38398-1.2	V299L	Pathogenic	0.691
BRCA1	P38398-1.2	V299M	Pathogenic	0.693
BRCA1	P38398-1.2	V299N	Pathogenic	0.882
BRCA1	P38398-1.2	V299P	Pathogenic	0.859
BRCA1	P38398-1.2	V299Q	Pathogenic	0.84
BRCA1	P38398-1.2	V299R	Pathogenic	0.94
BRCA1	P38398-1.2	V299S	Pathogenic	0.897
BRCA1	P38398-1.2	V299T	Pathogenic	0.732
BRCA1	P38398-1.2	V299W	Pathogenic	0.958
BRCA1	P38398-1.2	V299Y	Pathogenic	0.871
BRCA1	P38398-1.2	E300A	Pathogenic	0.987
BRCA1	P38398-1.2	E300C	Pathogenic	0.993
BRCA1	P38398-1.2	E300D	Pathogenic	0.938
BRCA1	P38398-1.2	E300F	Pathogenic	0.991
BRCA1	P38398-1.2	E300G	Pathogenic	0.994
BRCA1	P38398-1.2	E300H	Pathogenic	0.962
BRCA1	P38398-1.2	E300I	Pathogenic	0.988
BRCA1	P38398-1.2	E300K	Pathogenic	0.963
BRCA1	P38398-1.2	E300L	Pathogenic	0.988
BRCA1	P38398-1.2	E300M	Pathogenic	0.983
BRCA1	P38398-1.2	E300N	Pathogenic	0.965
BRCA1	P38398-1.2	E300P	Pathogenic	0.978
BRCA1	P38398-1.2	E300Q	Pathogenic	0.918
BRCA1	P38398-1.2	E300R	Pathogenic	0.98
BRCA1	P38398-1.2	E300S	Pathogenic	0.979
BRCA1	P38398-1.2	E300T	Pathogenic	0.977
BRCA1	P38398-1.2	E300V	Pathogenic	0.979
BRCA1	P38398-1.2	E300W	Pathogenic	0.995
BRCA1	P38398-1.2	E300Y	Pathogenic	0.988
BRCA1	P38398-1.2	K301A	Pathogenic	0.989
BRCA1	P38398-1.2	K301C	Pathogenic	0.992
BRCA1	P38398-1.2	K301D	Pathogenic	0.982
BRCA1	P38398-1.2	K301E	Pathogenic	0.946
BRCA1	P38398-1.2	K301F	Pathogenic	0.976
BRCA1	P38398-1.2	K301G	Pathogenic	0.995
BRCA1	P38398-1.2	K301H	Pathogenic	0.967
BRCA1	P38398-1.2	K301I	Pathogenic	0.981
BRCA1	P38398-1.2	K301L	Pathogenic	0.973
BRCA1	P38398-1.2	K301M	Pathogenic	0.961
BRCA1	P38398-1.2	K301N	Pathogenic	0.971
BRCA1	P38398-1.2	K301P	Pathogenic	0.982
BRCA1	P38398-1.2	K301Q	Pathogenic	0.939
BRCA1	P38398-1.2	K301R	Pathogenic	0.901
BRCA1	P38398-1.2	K301S	Pathogenic	0.982
BRCA1	P38398-1.2	K301T	Pathogenic	0.981
BRCA1	P38398-1.2	K301V	Pathogenic	0.982
BRCA1	P38398-1.2	K301W	Pathogenic	0.987
BRCA1	P38398-1.2	K301Y	Pathogenic	0.97
BRCA1	P38398-1.2	A302C	Pathogenic	0.925
BRCA1	P38398-1.2	A302D	Pathogenic	0.966
BRCA1	P38398-1.2	A302E	Pathogenic	0.967
BRCA1	P38398-1.2	A302F	Pathogenic	0.987
BRCA1	P38398-1.2	A302G	Pathogenic	0.925
BRCA1	P38398-1.2	A302H	Pathogenic	0.981
BRCA1	P38398-1.2	A302I	Pathogenic	0.976
BRCA1	P38398-1.2	A302K	Pathogenic	0.981
BRCA1	P38398-1.2	A302L	Pathogenic	0.976
BRCA1	P38398-1.2	A302M	Pathogenic	0.976
BRCA1	P38398-1.2	A302N	Pathogenic	0.969
BRCA1	P38398-1.2	A302P	Pathogenic	0.951
BRCA1	P38398-1.2	A302Q	Pathogenic	0.971
BRCA1	P38398-1.2	A302R	Pathogenic	0.986
BRCA1	P38398-1.2	A302S	Pathogenic	0.865
BRCA1	P38398-1.2	A302T	Pathogenic	0.935
BRCA1	P38398-1.2	A302V	Pathogenic	0.949
BRCA1	P38398-1.2	A302W	Pathogenic	0.995
BRCA1	P38398-1.2	A302Y	Pathogenic	0.989
BRCA1	P38398-1.2	E303A	Pathogenic	0.955
BRCA1	P38398-1.2	E303C	Pathogenic	0.976
BRCA1	P38398-1.2	E303D	Pathogenic	0.808
BRCA1	P38398-1.2	E303F	Pathogenic	0.967
BRCA1	P38398-1.2	E303G	Pathogenic	0.979
BRCA1	P38398-1.2	E303H	Pathogenic	0.876
BRCA1	P38398-1.2	E303I	Pathogenic	0.959
BRCA1	P38398-1.2	E303K	Pathogenic	0.878
BRCA1	P38398-1.2	E303L	Pathogenic	0.959
BRCA1	P38398-1.2	E303M	Pathogenic	0.942
BRCA1	P38398-1.2	E303N	Pathogenic	0.887
BRCA1	P38398-1.2	E303P	Pathogenic	0.926
BRCA1	P38398-1.2	E303Q	Pathogenic	0.758
BRCA1	P38398-1.2	E303R	Pathogenic	0.933
BRCA1	P38398-1.2	E303S	Pathogenic	0.928
BRCA1	P38398-1.2	E303T	Pathogenic	0.922
BRCA1	P38398-1.2	E303V	Pathogenic	0.928
BRCA1	P38398-1.2	E303W	Pathogenic	0.982
BRCA1	P38398-1.2	E303Y	Pathogenic	0.96
BRCA1	P38398-1.2	F304A	Pathogenic	0.901
BRCA1	P38398-1.2	F304C	Pathogenic	0.859
BRCA1	P38398-1.2	F304D	Pathogenic	0.883
BRCA1	P38398-1.2	F304E	Pathogenic	0.836
BRCA1	P38398-1.2	F304G	Pathogenic	0.952
BRCA1	P38398-1.2	F304H	Pathogenic	0.671
BRCA1	P38398-1.2	F304I	Pathogenic	0.562
BRCA1	P38398-1.2	F304K	Pathogenic	0.739
BRCA1	P38398-1.2	F304L	Pathogenic	0.561
BRCA1	P38398-1.2	F304M	Pathogenic	0.559
BRCA1	P38398-1.2	F304N	Pathogenic	0.872
BRCA1	P38398-1.2	F304P	Pathogenic	0.92
BRCA1	P38398-1.2	F304Q	Pathogenic	0.821
BRCA1	P38398-1.2	F304R	Pathogenic	0.791
BRCA1	P38398-1.2	F304S	Pathogenic	0.888
BRCA1	P38398-1.2	F304T	Pathogenic	0.837
BRCA1	P38398-1.2	F304V	Pathogenic	0.736
BRCA1	P38398-1.2	F304W	Pathogenic	0.563
BRCA1	P38398-1.2	F304Y	Neutral	0.275
BRCA1	P38398-1.2	C305A	Pathogenic	0.952
BRCA1	P38398-1.2	C305D	Pathogenic	0.977
BRCA1	P38398-1.2	C305E	Pathogenic	0.989
BRCA1	P38398-1.2	C305F	Pathogenic	0.988
BRCA1	P38398-1.2	C305G	Pathogenic	0.989
BRCA1	P38398-1.2	C305H	Pathogenic	0.988
BRCA1	P38398-1.2	C305I	Pathogenic	0.978
BRCA1	P38398-1.2	C305K	Pathogenic	0.991
BRCA1	P38398-1.2	C305L	Pathogenic	0.978
BRCA1	P38398-1.2	C305M	Pathogenic	0.978
BRCA1	P38398-1.2	C305N	Pathogenic	0.98
BRCA1	P38398-1.2	C305P	Pathogenic	0.977
BRCA1	P38398-1.2	C305Q	Pathogenic	0.986
BRCA1	P38398-1.2	C305R	Pathogenic	0.993
BRCA1	P38398-1.2	C305S	Pathogenic	0.962
BRCA1	P38398-1.2	C305T	Pathogenic	0.957
BRCA1	P38398-1.2	C305V	Pathogenic	0.967
BRCA1	P38398-1.2	C305W	Pathogenic	0.993
BRCA1	P38398-1.2	C305Y	Pathogenic	0.989
BRCA1	P38398-1.2	N306A	Pathogenic	0.828
BRCA1	P38398-1.2	N306C	Pathogenic	0.818
BRCA1	P38398-1.2	N306D	Neutral	0.49
BRCA1	P38398-1.2	N306E	Pathogenic	0.624
BRCA1	P38398-1.2	N306F	Pathogenic	0.894
BRCA1	P38398-1.2	N306G	Pathogenic	0.781
BRCA1	P38398-1.2	N306H	Pathogenic	0.581
BRCA1	P38398-1.2	N306I	Pathogenic	0.868
BRCA1	P38398-1.2	N306K	Pathogenic	0.746
BRCA1	P38398-1.2	N306L	Pathogenic	0.868
BRCA1	P38398-1.2	N306M	Pathogenic	0.822
BRCA1	P38398-1.2	N306P	Pathogenic	0.741
BRCA1	P38398-1.2	N306Q	Pathogenic	0.648
BRCA1	P38398-1.2	N306R	Pathogenic	0.796
BRCA1	P38398-1.2	N306S	Pathogenic	0.587
BRCA1	P38398-1.2	N306T	Pathogenic	0.566
BRCA1	P38398-1.2	N306V	Pathogenic	0.814
BRCA1	P38398-1.2	N306W	Pathogenic	0.957
BRCA1	P38398-1.2	N306Y	Pathogenic	0.871
BRCA1	P38398-1.2	K307A	Pathogenic	0.941
BRCA1	P38398-1.2	K307C	Pathogenic	0.956
BRCA1	P38398-1.2	K307D	Pathogenic	0.906
BRCA1	P38398-1.2	K307E	Pathogenic	0.756
BRCA1	P38398-1.2	K307F	Pathogenic	0.877
BRCA1	P38398-1.2	K307G	Pathogenic	0.973
BRCA1	P38398-1.2	K307H	Pathogenic	0.838
BRCA1	P38398-1.2	K307I	Pathogenic	0.901
BRCA1	P38398-1.2	K307L	Pathogenic	0.864
BRCA1	P38398-1.2	K307M	Pathogenic	0.816
BRCA1	P38398-1.2	K307N	Pathogenic	0.856
BRCA1	P38398-1.2	K307P	Pathogenic	0.905
BRCA1	P38398-1.2	K307Q	Pathogenic	0.734
BRCA1	P38398-1.2	K307R	Pathogenic	0.619
BRCA1	P38398-1.2	K307S	Pathogenic	0.908
BRCA1	P38398-1.2	K307T	Pathogenic	0.9
BRCA1	P38398-1.2	K307V	Pathogenic	0.907
BRCA1	P38398-1.2	K307W	Pathogenic	0.929
BRCA1	P38398-1.2	K307Y	Pathogenic	0.852
BRCA1	P38398-1.2	S308A	Pathogenic	0.892
BRCA1	P38398-1.2	S308C	Pathogenic	0.952
BRCA1	P38398-1.2	S308D	Pathogenic	0.939
BRCA1	P38398-1.2	S308E	Pathogenic	0.958
BRCA1	P38398-1.2	S308F	Pathogenic	0.988
BRCA1	P38398-1.2	S308G	Pathogenic	0.948
BRCA1	P38398-1.2	S308H	Pathogenic	0.976
BRCA1	P38398-1.2	S308I	Pathogenic	0.985
BRCA1	P38398-1.2	S308K	Pathogenic	0.976
BRCA1	P38398-1.2	S308L	Pathogenic	0.985
BRCA1	P38398-1.2	S308M	Pathogenic	0.979
BRCA1	P38398-1.2	S308N	Pathogenic	0.923
BRCA1	P38398-1.2	S308P	Pathogenic	0.956
BRCA1	P38398-1.2	S308Q	Pathogenic	0.963
BRCA1	P38398-1.2	S308R	Pathogenic	0.987
BRCA1	P38398-1.2	S308T	Pathogenic	0.919
BRCA1	P38398-1.2	S308V	Pathogenic	0.977
BRCA1	P38398-1.2	S308W	Pathogenic	0.995
BRCA1	P38398-1.2	S308Y	Pathogenic	0.99
BRCA1	P38398-1.2	K309A	Pathogenic	0.949
BRCA1	P38398-1.2	K309C	Pathogenic	0.961
BRCA1	P38398-1.2	K309D	Pathogenic	0.917
BRCA1	P38398-1.2	K309E	Pathogenic	0.781
BRCA1	P38398-1.2	K309F	Pathogenic	0.891
BRCA1	P38398-1.2	K309G	Pathogenic	0.976
BRCA1	P38398-1.2	K309H	Pathogenic	0.856
BRCA1	P38398-1.2	K309I	Pathogenic	0.913
BRCA1	P38398-1.2	K309L	Pathogenic	0.879
BRCA1	P38398-1.2	K309M	Pathogenic	0.836
BRCA1	P38398-1.2	K309N	Pathogenic	0.873
BRCA1	P38398-1.2	K309P	Pathogenic	0.917
BRCA1	P38398-1.2	K309Q	Pathogenic	0.76
BRCA1	P38398-1.2	K309R	Pathogenic	0.652
BRCA1	P38398-1.2	K309S	Pathogenic	0.919
BRCA1	P38398-1.2	K309T	Pathogenic	0.912
BRCA1	P38398-1.2	K309V	Pathogenic	0.918
BRCA1	P38398-1.2	K309W	Pathogenic	0.938
BRCA1	P38398-1.2	K309Y	Pathogenic	0.869
BRCA1	P38398-1.2	Q310A	Pathogenic	0.975
BRCA1	P38398-1.2	Q310C	Pathogenic	0.981
BRCA1	P38398-1.2	Q310D	Pathogenic	0.941
BRCA1	P38398-1.2	Q310E	Pathogenic	0.837
BRCA1	P38398-1.2	Q310F	Pathogenic	0.978
BRCA1	P38398-1.2	Q310G	Pathogenic	0.988
BRCA1	P38398-1.2	Q310H	Pathogenic	0.912
BRCA1	P38398-1.2	Q310I	Pathogenic	0.972
BRCA1	P38398-1.2	Q310K	Pathogenic	0.913
BRCA1	P38398-1.2	Q310L	Pathogenic	0.96
BRCA1	P38398-1.2	Q310M	Pathogenic	0.921
BRCA1	P38398-1.2	Q310N	Pathogenic	0.934
BRCA1	P38398-1.2	Q310P	Pathogenic	0.959
BRCA1	P38398-1.2	Q310R	Pathogenic	0.933
BRCA1	P38398-1.2	Q310S	Pathogenic	0.96
BRCA1	P38398-1.2	Q310T	Pathogenic	0.956
BRCA1	P38398-1.2	Q310V	Pathogenic	0.959
BRCA1	P38398-1.2	Q310W	Pathogenic	0.983
BRCA1	P38398-1.2	Q310Y	Pathogenic	0.961
BRCA1	P38398-1.2	P311A	Pathogenic	0.863
BRCA1	P38398-1.2	P311C	Pathogenic	0.895
BRCA1	P38398-1.2	P311D	Pathogenic	0.79
BRCA1	P38398-1.2	P311E	Pathogenic	0.849
BRCA1	P38398-1.2	P311F	Pathogenic	0.968
BRCA1	P38398-1.2	P311G	Pathogenic	0.932
BRCA1	P38398-1.2	P311H	Pathogenic	0.91
BRCA1	P38398-1.2	P311I	Pathogenic	0.942
BRCA1	P38398-1.2	P311K	Pathogenic	0.909
BRCA1	P38398-1.2	P311L	Pathogenic	0.943
BRCA1	P38398-1.2	P311M	Pathogenic	0.92
BRCA1	P38398-1.2	P311N	Pathogenic	0.859
BRCA1	P38398-1.2	P311Q	Pathogenic	0.864
BRCA1	P38398-1.2	P311R	Pathogenic	0.95
BRCA1	P38398-1.2	P311S	Pathogenic	0.845
BRCA1	P38398-1.2	P311T	Pathogenic	0.801
BRCA1	P38398-1.2	P311V	Pathogenic	0.883
BRCA1	P38398-1.2	P311W	Pathogenic	0.982
BRCA1	P38398-1.2	P311Y	Pathogenic	0.96
BRCA1	P38398-1.2	G312A	Neutral	0.251
BRCA1	P38398-1.2	G312C	Pathogenic	0.6
BRCA1	P38398-1.2	G312D	Neutral	0.449
BRCA1	P38398-1.2	G312E	Pathogenic	0.637
BRCA1	P38398-1.2	G312F	Pathogenic	0.815
BRCA1	P38398-1.2	G312H	Pathogenic	0.683
BRCA1	P38398-1.2	G312I	Pathogenic	0.832
BRCA1	P38398-1.2	G312K	Pathogenic	0.756
BRCA1	P38398-1.2	G312L	Pathogenic	0.832
BRCA1	P38398-1.2	G312M	Pathogenic	0.777
BRCA1	P38398-1.2	G312N	Neutral	0.388
BRCA1	P38398-1.2	G312P	Pathogenic	0.534
BRCA1	P38398-1.2	G312Q	Pathogenic	0.664
BRCA1	P38398-1.2	G312R	Pathogenic	0.805
BRCA1	P38398-1.2	G312S	Neutral	0.278
BRCA1	P38398-1.2	G312T	Pathogenic	0.553
BRCA1	P38398-1.2	G312V	Pathogenic	0.695
BRCA1	P38398-1.2	G312W	Pathogenic	0.849
BRCA1	P38398-1.2	G312Y	Pathogenic	0.836
BRCA1	P38398-1.2	L313A	Pathogenic	0.673
BRCA1	P38398-1.2	L313C	Pathogenic	0.577
BRCA1	P38398-1.2	L313D	Pathogenic	0.779
BRCA1	P38398-1.2	L313E	Pathogenic	0.622
BRCA1	P38398-1.2	L313F	Neutral	0.345
BRCA1	P38398-1.2	L313G	Pathogenic	0.903
BRCA1	P38398-1.2	L313H	Pathogenic	0.578
BRCA1	P38398-1.2	L313I	Neutral	0.166
BRCA1	P38398-1.2	L313K	Pathogenic	0.509
BRCA1	P38398-1.2	L313M	Neutral	0.165
BRCA1	P38398-1.2	L313N	Pathogenic	0.687
BRCA1	P38398-1.2	L313P	Pathogenic	0.72
BRCA1	P38398-1.2	L313Q	Pathogenic	0.508
BRCA1	P38398-1.2	L313R	Pathogenic	0.581
BRCA1	P38398-1.2	L313S	Pathogenic	0.72
BRCA1	P38398-1.2	L313T	Pathogenic	0.535
BRCA1	P38398-1.2	L313V	Neutral	0.303
BRCA1	P38398-1.2	L313W	Pathogenic	0.668
BRCA1	P38398-1.2	L313Y	Neutral	0.461
BRCA1	P38398-1.2	A314C	Pathogenic	0.632
BRCA1	P38398-1.2	A314D	Pathogenic	0.797
BRCA1	P38398-1.2	A314E	Pathogenic	0.804
BRCA1	P38398-1.2	A314F	Pathogenic	0.912
BRCA1	P38398-1.2	A314G	Pathogenic	0.633
BRCA1	P38398-1.2	A314H	Pathogenic	0.879
BRCA1	P38398-1.2	A314I	Pathogenic	0.85
BRCA1	P38398-1.2	A314K	Pathogenic	0.879
BRCA1	P38398-1.2	A314L	Pathogenic	0.85
BRCA1	P38398-1.2	A314M	Pathogenic	0.851
BRCA1	P38398-1.2	A314N	Pathogenic	0.815
BRCA1	P38398-1.2	A314P	Pathogenic	0.73
BRCA1	P38398-1.2	A314Q	Pathogenic	0.822
BRCA1	P38398-1.2	A314R	Pathogenic	0.906
BRCA1	P38398-1.2	A314S	Neutral	0.473
BRCA1	P38398-1.2	A314T	Pathogenic	0.67
BRCA1	P38398-1.2	A314V	Pathogenic	0.722
BRCA1	P38398-1.2	A314W	Pathogenic	0.965
BRCA1	P38398-1.2	A314Y	Pathogenic	0.923
BRCA1	P38398-1.2	R315A	Pathogenic	0.781
BRCA1	P38398-1.2	R315C	Pathogenic	0.827
BRCA1	P38398-1.2	R315D	Pathogenic	0.755
BRCA1	P38398-1.2	R315E	Neutral	0.498
BRCA1	P38398-1.2	R315F	Pathogenic	0.613
BRCA1	P38398-1.2	R315G	Pathogenic	0.887
BRCA1	P38398-1.2	R315H	Neutral	0.445
BRCA1	P38398-1.2	R315I	Pathogenic	0.669
BRCA1	P38398-1.2	R315K	Neutral	0.213
BRCA1	P38398-1.2	R315L	Pathogenic	0.585
BRCA1	P38398-1.2	R315M	Neutral	0.497
BRCA1	P38398-1.2	R315N	Pathogenic	0.57
BRCA1	P38398-1.2	R315P	Pathogenic	0.753
BRCA1	P38398-1.2	R315Q	Neutral	0.38
BRCA1	P38398-1.2	R315S	Pathogenic	0.759
BRCA1	P38398-1.2	R315T	Pathogenic	0.667
BRCA1	P38398-1.2	R315V	Pathogenic	0.757
BRCA1	P38398-1.2	R315W	Pathogenic	0.622
BRCA1	P38398-1.2	R315Y	Neutral	0.495
BRCA1	P38398-1.2	S316A	Pathogenic	0.869
BRCA1	P38398-1.2	S316C	Pathogenic	0.941
BRCA1	P38398-1.2	S316D	Pathogenic	0.925
BRCA1	P38398-1.2	S316E	Pathogenic	0.949
BRCA1	P38398-1.2	S316F	Pathogenic	0.985
BRCA1	P38398-1.2	S316G	Pathogenic	0.936
BRCA1	P38398-1.2	S316H	Pathogenic	0.97
BRCA1	P38398-1.2	S316I	Pathogenic	0.981
BRCA1	P38398-1.2	S316K	Pathogenic	0.97
BRCA1	P38398-1.2	S316L	Pathogenic	0.981
BRCA1	P38398-1.2	S316M	Pathogenic	0.973
BRCA1	P38398-1.2	S316N	Pathogenic	0.906
BRCA1	P38398-1.2	S316P	Pathogenic	0.946
BRCA1	P38398-1.2	S316Q	Pathogenic	0.954
BRCA1	P38398-1.2	S316R	Pathogenic	0.984
BRCA1	P38398-1.2	S316T	Pathogenic	0.9
BRCA1	P38398-1.2	S316V	Pathogenic	0.972
BRCA1	P38398-1.2	S316W	Pathogenic	0.994
BRCA1	P38398-1.2	S316Y	Pathogenic	0.987
BRCA1	P38398-1.2	Q317A	Pathogenic	0.983
BRCA1	P38398-1.2	Q317C	Pathogenic	0.987
BRCA1	P38398-1.2	Q317D	Pathogenic	0.96
BRCA1	P38398-1.2	Q317E	Pathogenic	0.885
BRCA1	P38398-1.2	Q317F	Pathogenic	0.985
BRCA1	P38398-1.2	Q317G	Pathogenic	0.992
BRCA1	P38398-1.2	Q317H	Pathogenic	0.94
BRCA1	P38398-1.2	Q317I	Pathogenic	0.981
BRCA1	P38398-1.2	Q317K	Pathogenic	0.94
BRCA1	P38398-1.2	Q317L	Pathogenic	0.973
BRCA1	P38398-1.2	Q317M	Pathogenic	0.946
BRCA1	P38398-1.2	Q317N	Pathogenic	0.955
BRCA1	P38398-1.2	Q317P	Pathogenic	0.972
BRCA1	P38398-1.2	Q317R	Pathogenic	0.955
BRCA1	P38398-1.2	Q317S	Pathogenic	0.973
BRCA1	P38398-1.2	Q317T	Pathogenic	0.97
BRCA1	P38398-1.2	Q317V	Pathogenic	0.973
BRCA1	P38398-1.2	Q317W	Pathogenic	0.988
BRCA1	P38398-1.2	Q317Y	Pathogenic	0.974
BRCA1	P38398-1.2	H318A	Pathogenic	0.575
BRCA1	P38398-1.2	H318C	Pathogenic	0.558
BRCA1	P38398-1.2	H318D	Neutral	0.352
BRCA1	P38398-1.2	H318E	Neutral	0.203
BRCA1	P38398-1.2	H318F	Neutral	0.3
BRCA1	P38398-1.2	H318G	Pathogenic	0.674
BRCA1	P38398-1.2	H318I	Neutral	0.41
BRCA1	P38398-1.2	H318K	Neutral	0.303
BRCA1	P38398-1.2	H318L	Neutral	0.411
BRCA1	P38398-1.2	H318M	Neutral	0.328
BRCA1	P38398-1.2	H318N	Neutral	0.191
BRCA1	P38398-1.2	H318P	Neutral	0.446
BRCA1	P38398-1.2	H318Q	Neutral	0.186
BRCA1	P38398-1.2	H318R	Neutral	0.287
BRCA1	P38398-1.2	H318S	Neutral	0.451
BRCA1	P38398-1.2	H318T	Neutral	0.432
BRCA1	P38398-1.2	H318V	Neutral	0.451
BRCA1	P38398-1.2	H318W	Pathogenic	0.533
BRCA1	P38398-1.2	H318Y	Neutral	0.143
BRCA1	P38398-1.2	N319A	Neutral	0.344
BRCA1	P38398-1.2	N319C	Neutral	0.328
BRCA1	P38398-1.2	N319D	Neutral	0.095
BRCA1	P38398-1.2	N319E	Neutral	0.153
BRCA1	P38398-1.2	N319F	Neutral	0.478
BRCA1	P38398-1.2	N319G	Neutral	0.28
BRCA1	P38398-1.2	N319H	Neutral	0.131
BRCA1	P38398-1.2	N319I	Neutral	0.417
BRCA1	P38398-1.2	N319K	Neutral	0.242
BRCA1	P38398-1.2	N319L	Neutral	0.418
BRCA1	P38398-1.2	N319M	Neutral	0.335
BRCA1	P38398-1.2	N319P	Neutral	0.238
BRCA1	P38398-1.2	N319Q	Neutral	0.167
BRCA1	P38398-1.2	N319R	Neutral	0.299
BRCA1	P38398-1.2	N319S	Neutral	0.134
BRCA1	P38398-1.2	N319T	Neutral	0.124
BRCA1	P38398-1.2	N319V	Neutral	0.322
BRCA1	P38398-1.2	N319W	Pathogenic	0.709
BRCA1	P38398-1.2	N319Y	Neutral	0.425
BRCA1	P38398-1.2	R320A	Pathogenic	0.991
BRCA1	P38398-1.2	R320C	Pathogenic	0.993
BRCA1	P38398-1.2	R320D	Pathogenic	0.989
BRCA1	P38398-1.2	R320E	Pathogenic	0.968
BRCA1	P38398-1.2	R320F	Pathogenic	0.98
BRCA1	P38398-1.2	R320G	Pathogenic	0.996
BRCA1	P38398-1.2	R320H	Pathogenic	0.961
BRCA1	P38398-1.2	R320I	Pathogenic	0.984
BRCA1	P38398-1.2	R320K	Pathogenic	0.892
BRCA1	P38398-1.2	R320L	Pathogenic	0.977
BRCA1	P38398-1.2	R320M	Pathogenic	0.968
BRCA1	P38398-1.2	R320N	Pathogenic	0.976
BRCA1	P38398-1.2	R320P	Pathogenic	0.989
BRCA1	P38398-1.2	R320Q	Pathogenic	0.949
BRCA1	P38398-1.2	R320S	Pathogenic	0.99
BRCA1	P38398-1.2	R320T	Pathogenic	0.984
BRCA1	P38398-1.2	R320V	Pathogenic	0.99
BRCA1	P38398-1.2	R320W	Pathogenic	0.98
BRCA1	P38398-1.2	R320Y	Pathogenic	0.968
BRCA1	P38398-1.2	W321A	Pathogenic	0.998
BRCA1	P38398-1.2	W321C	Pathogenic	0.995
BRCA1	P38398-1.2	W321D	Pathogenic	0.997
BRCA1	P38398-1.2	W321E	Pathogenic	0.994
BRCA1	P38398-1.2	W321F	Pathogenic	0.959
BRCA1	P38398-1.2	W321G	Pathogenic	0.998
BRCA1	P38398-1.2	W321H	Pathogenic	0.99
BRCA1	P38398-1.2	W321I	Pathogenic	0.992
BRCA1	P38398-1.2	W321K	Pathogenic	0.99
BRCA1	P38398-1.2	W321L	Pathogenic	0.989
BRCA1	P38398-1.2	W321M	Pathogenic	0.984
BRCA1	P38398-1.2	W321N	Pathogenic	0.997
BRCA1	P38398-1.2	W321P	Pathogenic	0.997
BRCA1	P38398-1.2	W321Q	Pathogenic	0.991
BRCA1	P38398-1.2	W321R	Pathogenic	0.986
BRCA1	P38398-1.2	W321S	Pathogenic	0.997
BRCA1	P38398-1.2	W321T	Pathogenic	0.994
BRCA1	P38398-1.2	W321V	Pathogenic	0.995
BRCA1	P38398-1.2	W321Y	Pathogenic	0.934
BRCA1	P38398-1.2	A322C	Pathogenic	0.555
BRCA1	P38398-1.2	A322D	Pathogenic	0.741
BRCA1	P38398-1.2	A322E	Pathogenic	0.748
BRCA1	P38398-1.2	A322F	Pathogenic	0.883
BRCA1	P38398-1.2	A322G	Pathogenic	0.556
BRCA1	P38398-1.2	A322H	Pathogenic	0.841
BRCA1	P38398-1.2	A322I	Pathogenic	0.804
BRCA1	P38398-1.2	A322K	Pathogenic	0.84
BRCA1	P38398-1.2	A322L	Pathogenic	0.804
BRCA1	P38398-1.2	A322M	Pathogenic	0.806
BRCA1	P38398-1.2	A322N	Pathogenic	0.762
BRCA1	P38398-1.2	A322P	Pathogenic	0.663
BRCA1	P38398-1.2	A322Q	Pathogenic	0.77
BRCA1	P38398-1.2	A322R	Pathogenic	0.875
BRCA1	P38398-1.2	A322S	Neutral	0.395
BRCA1	P38398-1.2	A322T	Pathogenic	0.595
BRCA1	P38398-1.2	A322V	Pathogenic	0.654
BRCA1	P38398-1.2	A322W	Pathogenic	0.952
BRCA1	P38398-1.2	A322Y	Pathogenic	0.897
BRCA1	P38398-1.2	G323A	Neutral	0.019
BRCA1	P38398-1.2	G323C	Neutral	0.082
BRCA1	P38398-1.2	G323D	Neutral	0.046
BRCA1	P38398-1.2	G323E	Neutral	0.094
BRCA1	P38398-1.2	G323F	Neutral	0.206
BRCA1	P38398-1.2	G323H	Neutral	0.113
BRCA1	P38398-1.2	G323I	Neutral	0.226
BRCA1	P38398-1.2	G323K	Neutral	0.155
BRCA1	P38398-1.2	G323L	Neutral	0.227
BRCA1	P38398-1.2	G323M	Neutral	0.171
BRCA1	P38398-1.2	G323N	Neutral	0.036
BRCA1	P38398-1.2	G323P	Neutral	0.064
BRCA1	P38398-1.2	G323Q	Neutral	0.105
BRCA1	P38398-1.2	G323R	Neutral	0.197
BRCA1	P38398-1.2	G323S	Neutral	0.022
BRCA1	P38398-1.2	G323T	Neutral	0.068
BRCA1	P38398-1.2	G323V	Neutral	0.119
BRCA1	P38398-1.2	G323W	Neutral	0.25
BRCA1	P38398-1.2	G323Y	Neutral	0.232
BRCA1	P38398-1.2	S324A	Neutral	0.134
BRCA1	P38398-1.2	S324C	Neutral	0.27
BRCA1	P38398-1.2	S324D	Neutral	0.224
BRCA1	P38398-1.2	S324E	Neutral	0.301
BRCA1	P38398-1.2	S324F	Pathogenic	0.608
BRCA1	P38398-1.2	S324G	Neutral	0.255
BRCA1	P38398-1.2	S324H	Neutral	0.433
BRCA1	P38398-1.2	S324I	Pathogenic	0.549
BRCA1	P38398-1.2	S324K	Neutral	0.433
BRCA1	P38398-1.2	S324L	Pathogenic	0.549
BRCA1	P38398-1.2	S324M	Neutral	0.461
BRCA1	P38398-1.2	S324N	Neutral	0.183
BRCA1	P38398-1.2	S324P	Neutral	0.289
BRCA1	P38398-1.2	S324Q	Neutral	0.327
BRCA1	P38398-1.2	S324R	Pathogenic	0.594
BRCA1	P38398-1.2	S324T	Neutral	0.174
BRCA1	P38398-1.2	S324V	Neutral	0.447
BRCA1	P38398-1.2	S324W	Pathogenic	0.805
BRCA1	P38398-1.2	S324Y	Pathogenic	0.643
BRCA1	P38398-1.2	K325A	Pathogenic	0.821
BRCA1	P38398-1.2	K325C	Pathogenic	0.86
BRCA1	P38398-1.2	K325D	Pathogenic	0.733
BRCA1	P38398-1.2	K325E	Neutral	0.47
BRCA1	P38398-1.2	K325F	Pathogenic	0.671
BRCA1	P38398-1.2	K325G	Pathogenic	0.91
BRCA1	P38398-1.2	K325H	Pathogenic	0.597
BRCA1	P38398-1.2	K325I	Pathogenic	0.722
BRCA1	P38398-1.2	K325L	Pathogenic	0.644
BRCA1	P38398-1.2	K325M	Pathogenic	0.559
BRCA1	P38398-1.2	K325N	Pathogenic	0.63
BRCA1	P38398-1.2	K325P	Pathogenic	0.732
BRCA1	P38398-1.2	K325Q	Neutral	0.44
BRCA1	P38398-1.2	K325R	Neutral	0.317
BRCA1	P38398-1.2	K325S	Pathogenic	0.737
BRCA1	P38398-1.2	K325T	Pathogenic	0.72
BRCA1	P38398-1.2	K325V	Pathogenic	0.736
BRCA1	P38398-1.2	K325W	Pathogenic	0.79
BRCA1	P38398-1.2	K325Y	Pathogenic	0.622
BRCA1	P38398-1.2	E326A	Pathogenic	0.505
BRCA1	P38398-1.2	E326C	Pathogenic	0.663
BRCA1	P38398-1.2	E326D	Neutral	0.169
BRCA1	P38398-1.2	E326F	Pathogenic	0.59
BRCA1	P38398-1.2	E326G	Pathogenic	0.692
BRCA1	P38398-1.2	E326H	Neutral	0.255
BRCA1	P38398-1.2	E326I	Pathogenic	0.53
BRCA1	P38398-1.2	E326K	Neutral	0.259
BRCA1	P38398-1.2	E326L	Pathogenic	0.53
BRCA1	P38398-1.2	E326M	Neutral	0.442
BRCA1	P38398-1.2	E326N	Neutral	0.275
BRCA1	P38398-1.2	E326P	Neutral	0.378
BRCA1	P38398-1.2	E326Q	Neutral	0.132
BRCA1	P38398-1.2	E326R	Neutral	0.401
BRCA1	P38398-1.2	E326S	Neutral	0.384
BRCA1	P38398-1.2	E326T	Neutral	0.364
BRCA1	P38398-1.2	E326V	Neutral	0.383
BRCA1	P38398-1.2	E326W	Pathogenic	0.726
BRCA1	P38398-1.2	E326Y	Pathogenic	0.537
BRCA1	P38398-1.2	T327A	Neutral	0.417
BRCA1	P38398-1.2	T327C	Neutral	0.4
BRCA1	P38398-1.2	T327D	Neutral	0.372
BRCA1	P38398-1.2	T327E	Neutral	0.448
BRCA1	P38398-1.2	T327F	Pathogenic	0.673
BRCA1	P38398-1.2	T327G	Pathogenic	0.692
BRCA1	P38398-1.2	T327H	Pathogenic	0.591
BRCA1	P38398-1.2	T327I	Pathogenic	0.528
BRCA1	P38398-1.2	T327K	Pathogenic	0.59
BRCA1	P38398-1.2	T327L	Pathogenic	0.528
BRCA1	P38398-1.2	T327M	Pathogenic	0.531
BRCA1	P38398-1.2	T327N	Neutral	0.297
BRCA1	P38398-1.2	T327P	Neutral	0.38
BRCA1	P38398-1.2	T327Q	Neutral	0.478
BRCA1	P38398-1.2	T327R	Pathogenic	0.657
BRCA1	P38398-1.2	T327S	Neutral	0.302
BRCA1	P38398-1.2	T327V	Neutral	0.34
BRCA1	P38398-1.2	T327W	Pathogenic	0.791
BRCA1	P38398-1.2	T327Y	Pathogenic	0.705
BRCA1	P38398-1.2	C328A	Pathogenic	0.862
BRCA1	P38398-1.2	C328D	Pathogenic	0.93
BRCA1	P38398-1.2	C328E	Pathogenic	0.966
BRCA1	P38398-1.2	C328F	Pathogenic	0.962
BRCA1	P38398-1.2	C328G	Pathogenic	0.966
BRCA1	P38398-1.2	C328H	Pathogenic	0.961
BRCA1	P38398-1.2	C328I	Pathogenic	0.932
BRCA1	P38398-1.2	C328K	Pathogenic	0.972
BRCA1	P38398-1.2	C328L	Pathogenic	0.932
BRCA1	P38398-1.2	C328M	Pathogenic	0.932
BRCA1	P38398-1.2	C328N	Pathogenic	0.937
BRCA1	P38398-1.2	C328P	Pathogenic	0.931
BRCA1	P38398-1.2	C328Q	Pathogenic	0.957
BRCA1	P38398-1.2	C328R	Pathogenic	0.979
BRCA1	P38398-1.2	C328S	Pathogenic	0.886
BRCA1	P38398-1.2	C328T	Pathogenic	0.873
BRCA1	P38398-1.2	C328V	Pathogenic	0.901
BRCA1	P38398-1.2	C328W	Pathogenic	0.979
BRCA1	P38398-1.2	C328Y	Pathogenic	0.967
BRCA1	P38398-1.2	N329A	Neutral	0.146
BRCA1	P38398-1.2	N329C	Neutral	0.138
BRCA1	P38398-1.2	N329D	Neutral	0.033
BRCA1	P38398-1.2	N329E	Neutral	0.056
BRCA1	P38398-1.2	N329F	Neutral	0.231
BRCA1	P38398-1.2	N329G	Neutral	0.113
BRCA1	P38398-1.2	N329H	Neutral	0.047
BRCA1	P38398-1.2	N329I	Neutral	0.19
BRCA1	P38398-1.2	N329K	Neutral	0.095
BRCA1	P38398-1.2	N329L	Neutral	0.19
BRCA1	P38398-1.2	N329M	Neutral	0.142
BRCA1	P38398-1.2	N329P	Neutral	0.093
BRCA1	P38398-1.2	N329Q	Neutral	0.062
BRCA1	P38398-1.2	N329R	Neutral	0.122
BRCA1	P38398-1.2	N329S	Neutral	0.048
BRCA1	P38398-1.2	N329T	Neutral	0.044
BRCA1	P38398-1.2	N329V	Neutral	0.135
BRCA1	P38398-1.2	N329W	Neutral	0.443
BRCA1	P38398-1.2	N329Y	Neutral	0.195
BRCA1	P38398-1.2	D330A	Pathogenic	0.886
BRCA1	P38398-1.2	D330C	Pathogenic	0.879
BRCA1	P38398-1.2	D330E	Pathogenic	0.619
BRCA1	P38398-1.2	D330F	Pathogenic	0.945
BRCA1	P38398-1.2	D330G	Pathogenic	0.893
BRCA1	P38398-1.2	D330H	Pathogenic	0.853
BRCA1	P38398-1.2	D330I	Pathogenic	0.93
BRCA1	P38398-1.2	D330K	Pathogenic	0.896
BRCA1	P38398-1.2	D330L	Pathogenic	0.951
BRCA1	P38398-1.2	D330M	Pathogenic	0.931
BRCA1	P38398-1.2	D330N	Pathogenic	0.636
BRCA1	P38398-1.2	D330P	Pathogenic	0.763
BRCA1	P38398-1.2	D330Q	Pathogenic	0.788
BRCA1	P38398-1.2	D330R	Pathogenic	0.943
BRCA1	P38398-1.2	D330S	Pathogenic	0.769
BRCA1	P38398-1.2	D330T	Pathogenic	0.769
BRCA1	P38398-1.2	D330V	Pathogenic	0.898
BRCA1	P38398-1.2	D330W	Pathogenic	0.978
BRCA1	P38398-1.2	D330Y	Pathogenic	0.952
BRCA1	P38398-1.2	R331A	Pathogenic	0.891
BRCA1	P38398-1.2	R331C	Pathogenic	0.917
BRCA1	P38398-1.2	R331D	Pathogenic	0.876
BRCA1	P38398-1.2	R331E	Pathogenic	0.695
BRCA1	P38398-1.2	R331F	Pathogenic	0.785
BRCA1	P38398-1.2	R331G	Pathogenic	0.948
BRCA1	P38398-1.2	R331H	Pathogenic	0.648
BRCA1	P38398-1.2	R331I	Pathogenic	0.823
BRCA1	P38398-1.2	R331K	Neutral	0.384
BRCA1	P38398-1.2	R331L	Pathogenic	0.764
BRCA1	P38398-1.2	R331M	Pathogenic	0.694
BRCA1	P38398-1.2	R331N	Pathogenic	0.753
BRCA1	P38398-1.2	R331P	Pathogenic	0.875
BRCA1	P38398-1.2	R331Q	Pathogenic	0.584
BRCA1	P38398-1.2	R331S	Pathogenic	0.878
BRCA1	P38398-1.2	R331T	Pathogenic	0.821
BRCA1	P38398-1.2	R331V	Pathogenic	0.878
BRCA1	P38398-1.2	R331W	Pathogenic	0.79
BRCA1	P38398-1.2	R331Y	Pathogenic	0.692
BRCA1	P38398-1.2	R332A	Pathogenic	0.625
BRCA1	P38398-1.2	R332C	Pathogenic	0.691
BRCA1	P38398-1.2	R332D	Pathogenic	0.589
BRCA1	P38398-1.2	R332E	Neutral	0.317
BRCA1	P38398-1.2	R332F	Neutral	0.425
BRCA1	P38398-1.2	R332G	Pathogenic	0.786
BRCA1	P38398-1.2	R332H	Neutral	0.272
BRCA1	P38398-1.2	R332I	Neutral	0.486
BRCA1	P38398-1.2	R332K	Neutral	0.112
BRCA1	P38398-1.2	R332L	Neutral	0.397
BRCA1	P38398-1.2	R332M	Neutral	0.316
BRCA1	P38398-1.2	R332N	Neutral	0.382
BRCA1	P38398-1.2	R332P	Pathogenic	0.588
BRCA1	P38398-1.2	R332Q	Neutral	0.222
BRCA1	P38398-1.2	R332S	Pathogenic	0.595
BRCA1	P38398-1.2	R332T	Neutral	0.483
BRCA1	P38398-1.2	R332V	Pathogenic	0.593
BRCA1	P38398-1.2	R332W	Neutral	0.434
BRCA1	P38398-1.2	R332Y	Neutral	0.314
BRCA1	P38398-1.2	T333A	Neutral	0.052
BRCA1	P38398-1.2	T333C	Neutral	0.049
BRCA1	P38398-1.2	T333D	Neutral	0.044
BRCA1	P38398-1.2	T333E	Neutral	0.059
BRCA1	P38398-1.2	T333F	Neutral	0.137
BRCA1	P38398-1.2	T333G	Neutral	0.148
BRCA1	P38398-1.2	T333H	Neutral	0.1
BRCA1	P38398-1.2	T333I	Neutral	0.079
BRCA1	P38398-1.2	T333K	Neutral	0.1
BRCA1	P38398-1.2	T333L	Neutral	0.079
BRCA1	P38398-1.2	T333M	Neutral	0.08
BRCA1	P38398-1.2	T333N	Neutral	0.032
BRCA1	P38398-1.2	T333P	Neutral	0.045
BRCA1	P38398-1.2	T333Q	Neutral	0.066
BRCA1	P38398-1.2	T333R	Neutral	0.129
BRCA1	P38398-1.2	T333S	Neutral	0.032
BRCA1	P38398-1.2	T333V	Neutral	0.038
BRCA1	P38398-1.2	T333W	Neutral	0.226
BRCA1	P38398-1.2	T333Y	Neutral	0.155
BRCA1	P38398-1.2	P334A	Pathogenic	0.736
BRCA1	P38398-1.2	P334C	Pathogenic	0.791
BRCA1	P38398-1.2	P334D	Pathogenic	0.626
BRCA1	P38398-1.2	P334E	Pathogenic	0.714
BRCA1	P38398-1.2	P334F	Pathogenic	0.93
BRCA1	P38398-1.2	P334G	Pathogenic	0.859
BRCA1	P38398-1.2	P334H	Pathogenic	0.817
BRCA1	P38398-1.2	P334I	Pathogenic	0.879
BRCA1	P38398-1.2	P334K	Pathogenic	0.816
BRCA1	P38398-1.2	P334L	Pathogenic	0.879
BRCA1	P38398-1.2	P334M	Pathogenic	0.836
BRCA1	P38398-1.2	P334N	Pathogenic	0.73
BRCA1	P38398-1.2	P334Q	Pathogenic	0.738
BRCA1	P38398-1.2	P334R	Pathogenic	0.895
BRCA1	P38398-1.2	P334S	Pathogenic	0.708
BRCA1	P38398-1.2	P334T	Pathogenic	0.641
BRCA1	P38398-1.2	P334V	Pathogenic	0.77
BRCA1	P38398-1.2	P334W	Pathogenic	0.961
BRCA1	P38398-1.2	P334Y	Pathogenic	0.915
BRCA1	P38398-1.2	S335A	Neutral	0.117
BRCA1	P38398-1.2	S335C	Neutral	0.241
BRCA1	P38398-1.2	S335D	Neutral	0.198
BRCA1	P38398-1.2	S335E	Neutral	0.27
BRCA1	P38398-1.2	S335F	Pathogenic	0.571
BRCA1	P38398-1.2	S335G	Neutral	0.226
BRCA1	P38398-1.2	S335H	Neutral	0.396
BRCA1	P38398-1.2	S335I	Pathogenic	0.511
BRCA1	P38398-1.2	S335K	Neutral	0.396
BRCA1	P38398-1.2	S335L	Pathogenic	0.511
BRCA1	P38398-1.2	S335M	Neutral	0.423
BRCA1	P38398-1.2	S335N	Neutral	0.162
BRCA1	P38398-1.2	S335P	Neutral	0.258
BRCA1	P38398-1.2	S335Q	Neutral	0.294
BRCA1	P38398-1.2	S335R	Pathogenic	0.557
BRCA1	P38398-1.2	S335T	Neutral	0.153
BRCA1	P38398-1.2	S335V	Neutral	0.409
BRCA1	P38398-1.2	S335W	Pathogenic	0.78
BRCA1	P38398-1.2	S335Y	Pathogenic	0.607
BRCA1	P38398-1.2	T336A	Pathogenic	0.659
BRCA1	P38398-1.2	T336C	Pathogenic	0.642
BRCA1	P38398-1.2	T336D	Pathogenic	0.615
BRCA1	P38398-1.2	T336E	Pathogenic	0.686
BRCA1	P38398-1.2	T336F	Pathogenic	0.847
BRCA1	P38398-1.2	T336G	Pathogenic	0.858
BRCA1	P38398-1.2	T336H	Pathogenic	0.796
BRCA1	P38398-1.2	T336I	Pathogenic	0.751
BRCA1	P38398-1.2	T336K	Pathogenic	0.795
BRCA1	P38398-1.2	T336L	Pathogenic	0.751
BRCA1	P38398-1.2	T336M	Pathogenic	0.753
BRCA1	P38398-1.2	T336N	Pathogenic	0.533
BRCA1	P38398-1.2	T336P	Pathogenic	0.623
BRCA1	P38398-1.2	T336Q	Pathogenic	0.711
BRCA1	P38398-1.2	T336R	Pathogenic	0.838
BRCA1	P38398-1.2	T336S	Pathogenic	0.539
BRCA1	P38398-1.2	T336V	Pathogenic	0.581
BRCA1	P38398-1.2	T336W	Pathogenic	0.911
BRCA1	P38398-1.2	T336Y	Pathogenic	0.865
BRCA1	P38398-1.2	E337A	Pathogenic	0.937
BRCA1	P38398-1.2	E337C	Pathogenic	0.966
BRCA1	P38398-1.2	E337D	Pathogenic	0.748
BRCA1	P38398-1.2	E337F	Pathogenic	0.955
BRCA1	P38398-1.2	E337G	Pathogenic	0.97
BRCA1	P38398-1.2	E337H	Pathogenic	0.833
BRCA1	P38398-1.2	E337I	Pathogenic	0.943
BRCA1	P38398-1.2	E337K	Pathogenic	0.836
BRCA1	P38398-1.2	E337L	Pathogenic	0.943
BRCA1	P38398-1.2	E337M	Pathogenic	0.92
BRCA1	P38398-1.2	E337N	Pathogenic	0.847
BRCA1	P38398-1.2	E337P	Pathogenic	0.899
BRCA1	P38398-1.2	E337Q	Pathogenic	0.689
BRCA1	P38398-1.2	E337R	Pathogenic	0.907
BRCA1	P38398-1.2	E337S	Pathogenic	0.901
BRCA1	P38398-1.2	E337T	Pathogenic	0.893
BRCA1	P38398-1.2	E337V	Pathogenic	0.9
BRCA1	P38398-1.2	E337W	Pathogenic	0.975
BRCA1	P38398-1.2	E337Y	Pathogenic	0.944
BRCA1	P38398-1.2	K338A	Neutral	0.065
BRCA1	P38398-1.2	K338C	Neutral	0.085
BRCA1	P38398-1.2	K338D	Neutral	0.04
BRCA1	P38398-1.2	K338E	Neutral	0.013
BRCA1	P38398-1.2	K338F	Neutral	0.03
BRCA1	P38398-1.2	K338G	Neutral	0.133
BRCA1	P38398-1.2	K338H	Neutral	0.022
BRCA1	P38398-1.2	K338I	Neutral	0.038
BRCA1	P38398-1.2	K338L	Neutral	0.027
BRCA1	P38398-1.2	K338M	Neutral	0.019
BRCA1	P38398-1.2	K338N	Neutral	0.025
BRCA1	P38398-1.2	K338P	Neutral	0.04
BRCA1	P38398-1.2	K338Q	Neutral	0.012
BRCA1	P38398-1.2	K338R	Neutral	0.007
BRCA1	P38398-1.2	K338S	Neutral	0.041
BRCA1	P38398-1.2	K338T	Neutral	0.038
BRCA1	P38398-1.2	K338V	Neutral	0.041
BRCA1	P38398-1.2	K338W	Neutral	0.054
BRCA1	P38398-1.2	K338Y	Neutral	0.024
BRCA1	P38398-1.2	K339A	Neutral	0.416
BRCA1	P38398-1.2	K339C	Neutral	0.489
BRCA1	P38398-1.2	K339D	Neutral	0.299
BRCA1	P38398-1.2	K339E	Neutral	0.121
BRCA1	P38398-1.2	K339F	Neutral	0.241
BRCA1	P38398-1.2	K339G	Pathogenic	0.611
BRCA1	P38398-1.2	K339H	Neutral	0.187
BRCA1	P38398-1.2	K339I	Neutral	0.288
BRCA1	P38398-1.2	K339L	Neutral	0.22
BRCA1	P38398-1.2	K339M	Neutral	0.165
BRCA1	P38398-1.2	K339N	Neutral	0.209
BRCA1	P38398-1.2	K339P	Neutral	0.298
BRCA1	P38398-1.2	K339Q	Neutral	0.109
BRCA1	P38398-1.2	K339R	Neutral	0.067
BRCA1	P38398-1.2	K339S	Neutral	0.304
BRCA1	P38398-1.2	K339T	Neutral	0.286
BRCA1	P38398-1.2	K339V	Neutral	0.302
BRCA1	P38398-1.2	K339W	Neutral	0.369
BRCA1	P38398-1.2	K339Y	Neutral	0.203
BRCA1	P38398-1.2	V340A	Neutral	0.15
BRCA1	P38398-1.2	V340C	Neutral	0.144
BRCA1	P38398-1.2	V340D	Neutral	0.232
BRCA1	P38398-1.2	V340E	Neutral	0.144
BRCA1	P38398-1.2	V340F	Neutral	0.176
BRCA1	P38398-1.2	V340G	Neutral	0.443
BRCA1	P38398-1.2	V340H	Neutral	0.231
BRCA1	P38398-1.2	V340I	Neutral	0.038
BRCA1	P38398-1.2	V340K	Neutral	0.23
BRCA1	P38398-1.2	V340L	Neutral	0.075
BRCA1	P38398-1.2	V340M	Neutral	0.075
BRCA1	P38398-1.2	V340N	Neutral	0.213
BRCA1	P38398-1.2	V340P	Neutral	0.181
BRCA1	P38398-1.2	V340Q	Neutral	0.159
BRCA1	P38398-1.2	V340R	Neutral	0.364
BRCA1	P38398-1.2	V340S	Neutral	0.241
BRCA1	P38398-1.2	V340T	Neutral	0.09
BRCA1	P38398-1.2	V340W	Neutral	0.45
BRCA1	P38398-1.2	V340Y	Neutral	0.197
BRCA1	P38398-1.2	D341A	Neutral	0.009
BRCA1	P38398-1.2	D341C	Neutral	0.008
BRCA1	P38398-1.2	D341E	Neutral	0.002
BRCA1	P38398-1.2	D341F	Neutral	0.019
BRCA1	P38398-1.2	D341G	Neutral	0.009
BRCA1	P38398-1.2	D341H	Neutral	0.007
BRCA1	P38398-1.2	D341I	Neutral	0.015
BRCA1	P38398-1.2	D341K	Neutral	0.01
BRCA1	P38398-1.2	D341L	Neutral	0.021
BRCA1	P38398-1.2	D341M	Neutral	0.015
BRCA1	P38398-1.2	D341N	Neutral	0.002
BRCA1	P38398-1.2	D341P	Neutral	0.004
BRCA1	P38398-1.2	D341Q	Neutral	0.004
BRCA1	P38398-1.2	D341R	Neutral	0.018
BRCA1	P38398-1.2	D341S	Neutral	0.004
BRCA1	P38398-1.2	D341T	Neutral	0.004
BRCA1	P38398-1.2	D341V	Neutral	0.01
BRCA1	P38398-1.2	D341W	Neutral	0.049
BRCA1	P38398-1.2	D341Y	Neutral	0.022
BRCA1	P38398-1.2	L342A	Neutral	0.161
BRCA1	P38398-1.2	L342C	Neutral	0.113
BRCA1	P38398-1.2	L342D	Neutral	0.247
BRCA1	P38398-1.2	L342E	Neutral	0.133
BRCA1	P38398-1.2	L342F	Neutral	0.047
BRCA1	P38398-1.2	L342G	Neutral	0.464
BRCA1	P38398-1.2	L342H	Neutral	0.113
BRCA1	P38398-1.2	L342I	Neutral	0.018
BRCA1	P38398-1.2	L342K	Neutral	0.088
BRCA1	P38398-1.2	L342M	Neutral	0.018
BRCA1	P38398-1.2	L342N	Neutral	0.17
BRCA1	P38398-1.2	L342P	Neutral	0.193
BRCA1	P38398-1.2	L342Q	Neutral	0.088
BRCA1	P38398-1.2	L342R	Neutral	0.114
BRCA1	P38398-1.2	L342S	Neutral	0.193
BRCA1	P38398-1.2	L342T	Neutral	0.097
BRCA1	P38398-1.2	L342V	Neutral	0.039
BRCA1	P38398-1.2	L342W	Neutral	0.158
BRCA1	P38398-1.2	L342Y	Neutral	0.074
BRCA1	P38398-1.2	N343A	Neutral	0.116
BRCA1	P38398-1.2	N343C	Neutral	0.109
BRCA1	P38398-1.2	N343D	Neutral	0.026
BRCA1	P38398-1.2	N343E	Neutral	0.043
BRCA1	P38398-1.2	N343F	Neutral	0.187
BRCA1	P38398-1.2	N343G	Neutral	0.089
BRCA1	P38398-1.2	N343H	Neutral	0.036
BRCA1	P38398-1.2	N343I	Neutral	0.152
BRCA1	P38398-1.2	N343K	Neutral	0.074
BRCA1	P38398-1.2	N343L	Neutral	0.153
BRCA1	P38398-1.2	N343M	Neutral	0.112
BRCA1	P38398-1.2	N343P	Neutral	0.073
BRCA1	P38398-1.2	N343Q	Neutral	0.048
BRCA1	P38398-1.2	N343R	Neutral	0.097
BRCA1	P38398-1.2	N343S	Neutral	0.037
BRCA1	P38398-1.2	N343T	Neutral	0.034
BRCA1	P38398-1.2	N343V	Neutral	0.107
BRCA1	P38398-1.2	N343W	Neutral	0.379
BRCA1	P38398-1.2	N343Y	Neutral	0.156
BRCA1	P38398-1.2	A344C	Neutral	0.275
BRCA1	P38398-1.2	A344D	Neutral	0.465
BRCA1	P38398-1.2	A344E	Neutral	0.475
BRCA1	P38398-1.2	A344F	Pathogenic	0.696
BRCA1	P38398-1.2	A344G	Neutral	0.276
BRCA1	P38398-1.2	A344H	Pathogenic	0.617
BRCA1	P38398-1.2	A344I	Pathogenic	0.555
BRCA1	P38398-1.2	A344K	Pathogenic	0.615
BRCA1	P38398-1.2	A344L	Pathogenic	0.555
BRCA1	P38398-1.2	A344M	Pathogenic	0.558
BRCA1	P38398-1.2	A344N	Neutral	0.494
BRCA1	P38398-1.2	A344P	Neutral	0.374
BRCA1	P38398-1.2	A344Q	Pathogenic	0.504
BRCA1	P38398-1.2	A344R	Pathogenic	0.681
BRCA1	P38398-1.2	A344S	Neutral	0.166
BRCA1	P38398-1.2	A344T	Neutral	0.309
BRCA1	P38398-1.2	A344V	Neutral	0.365
BRCA1	P38398-1.2	A344W	Pathogenic	0.859
BRCA1	P38398-1.2	A344Y	Pathogenic	0.727
BRCA1	P38398-1.2	D345A	Neutral	0.219
BRCA1	P38398-1.2	D345C	Neutral	0.207
BRCA1	P38398-1.2	D345E	Neutral	0.055
BRCA1	P38398-1.2	D345F	Neutral	0.38
BRCA1	P38398-1.2	D345G	Neutral	0.23
BRCA1	P38398-1.2	D345H	Neutral	0.173
BRCA1	P38398-1.2	D345I	Neutral	0.324
BRCA1	P38398-1.2	D345K	Neutral	0.236
BRCA1	P38398-1.2	D345L	Neutral	0.409
BRCA1	P38398-1.2	D345M	Neutral	0.326
BRCA1	P38398-1.2	D345N	Neutral	0.059
BRCA1	P38398-1.2	D345P	Neutral	0.104
BRCA1	P38398-1.2	D345Q	Neutral	0.118
BRCA1	P38398-1.2	D345R	Neutral	0.372
BRCA1	P38398-1.2	D345S	Neutral	0.107
BRCA1	P38398-1.2	D345T	Neutral	0.107
BRCA1	P38398-1.2	D345V	Neutral	0.241
BRCA1	P38398-1.2	D345W	Pathogenic	0.619
BRCA1	P38398-1.2	D345Y	Neutral	0.415
BRCA1	P38398-1.2	P346A	Neutral	0.083
BRCA1	P38398-1.2	P346C	Neutral	0.11
BRCA1	P38398-1.2	P346D	Neutral	0.052
BRCA1	P38398-1.2	P346E	Neutral	0.076
BRCA1	P38398-1.2	P346F	Neutral	0.304
BRCA1	P38398-1.2	P346G	Neutral	0.166
BRCA1	P38398-1.2	P346H	Neutral	0.127
BRCA1	P38398-1.2	P346I	Neutral	0.192
BRCA1	P38398-1.2	P346K	Neutral	0.126
BRCA1	P38398-1.2	P346L	Neutral	0.192
BRCA1	P38398-1.2	P346M	Neutral	0.143
BRCA1	P38398-1.2	P346N	Neutral	0.081
BRCA1	P38398-1.2	P346Q	Neutral	0.084
BRCA1	P38398-1.2	P346R	Neutral	0.217
BRCA1	P38398-1.2	P346S	Neutral	0.073
BRCA1	P38398-1.2	P346T	Neutral	0.055
BRCA1	P38398-1.2	P346V	Neutral	0.099
BRCA1	P38398-1.2	P346W	Neutral	0.446
BRCA1	P38398-1.2	P346Y	Neutral	0.26
BRCA1	P38398-1.2	L347A	Pathogenic	0.76
BRCA1	P38398-1.2	L347C	Pathogenic	0.678
BRCA1	P38398-1.2	L347D	Pathogenic	0.845
BRCA1	P38398-1.2	L347E	Pathogenic	0.717
BRCA1	P38398-1.2	L347F	Neutral	0.449
BRCA1	P38398-1.2	L347G	Pathogenic	0.935
BRCA1	P38398-1.2	L347H	Pathogenic	0.678
BRCA1	P38398-1.2	L347I	Neutral	0.235
BRCA1	P38398-1.2	L347K	Pathogenic	0.616
BRCA1	P38398-1.2	L347M	Neutral	0.234
BRCA1	P38398-1.2	L347N	Pathogenic	0.772
BRCA1	P38398-1.2	L347P	Pathogenic	0.799
BRCA1	P38398-1.2	L347Q	Pathogenic	0.614
BRCA1	P38398-1.2	L347R	Pathogenic	0.682
BRCA1	P38398-1.2	L347S	Pathogenic	0.799
BRCA1	P38398-1.2	L347T	Pathogenic	0.64
BRCA1	P38398-1.2	L347V	Neutral	0.401
BRCA1	P38398-1.2	L347W	Pathogenic	0.757
BRCA1	P38398-1.2	L347Y	Pathogenic	0.569
BRCA1	P38398-1.2	C348A	Neutral	0.008
BRCA1	P38398-1.2	C348D	Neutral	0.016
BRCA1	P38398-1.2	C348E	Neutral	0.035
BRCA1	P38398-1.2	C348F	Neutral	0.03
BRCA1	P38398-1.2	C348G	Neutral	0.034
BRCA1	P38398-1.2	C348H	Neutral	0.03
BRCA1	P38398-1.2	C348I	Neutral	0.017
BRCA1	P38398-1.2	C348K	Neutral	0.042
BRCA1	P38398-1.2	C348L	Neutral	0.017
BRCA1	P38398-1.2	C348M	Neutral	0.017
BRCA1	P38398-1.2	C348N	Neutral	0.018
BRCA1	P38398-1.2	C348P	Neutral	0.016
BRCA1	P38398-1.2	C348Q	Neutral	0.027
BRCA1	P38398-1.2	C348R	Neutral	0.055
BRCA1	P38398-1.2	C348S	Neutral	0.01
BRCA1	P38398-1.2	C348T	Neutral	0.008
BRCA1	P38398-1.2	C348V	Neutral	0.011
BRCA1	P38398-1.2	C348W	Neutral	0.055
BRCA1	P38398-1.2	C348Y	Neutral	0.035
BRCA1	P38398-1.2	E349A	Neutral	0.05
BRCA1	P38398-1.2	E349C	Neutral	0.093
BRCA1	P38398-1.2	E349D	Neutral	0.01
BRCA1	P38398-1.2	E349F	Neutral	0.07
BRCA1	P38398-1.2	E349G	Neutral	0.105
BRCA1	P38398-1.2	E349H	Neutral	0.017
BRCA1	P38398-1.2	E349I	Neutral	0.055
BRCA1	P38398-1.2	E349K	Neutral	0.018
BRCA1	P38398-1.2	E349L	Neutral	0.055
BRCA1	P38398-1.2	E349M	Neutral	0.04
BRCA1	P38398-1.2	E349N	Neutral	0.019
BRCA1	P38398-1.2	E349P	Neutral	0.031
BRCA1	P38398-1.2	E349Q	Neutral	0.008
BRCA1	P38398-1.2	E349R	Neutral	0.034
BRCA1	P38398-1.2	E349S	Neutral	0.031
BRCA1	P38398-1.2	E349T	Neutral	0.029
BRCA1	P38398-1.2	E349V	Neutral	0.031
BRCA1	P38398-1.2	E349W	Neutral	0.121
BRCA1	P38398-1.2	E349Y	Neutral	0.057
BRCA1	P38398-1.2	R350A	Pathogenic	0.779
BRCA1	P38398-1.2	R350C	Pathogenic	0.825
BRCA1	P38398-1.2	R350D	Pathogenic	0.752
BRCA1	P38398-1.2	R350E	Neutral	0.495
BRCA1	P38398-1.2	R350F	Pathogenic	0.61
BRCA1	P38398-1.2	R350G	Pathogenic	0.886
BRCA1	P38398-1.2	R350H	Neutral	0.441
BRCA1	P38398-1.2	R350I	Pathogenic	0.666
BRCA1	P38398-1.2	R350K	Neutral	0.211
BRCA1	P38398-1.2	R350L	Pathogenic	0.582
BRCA1	P38398-1.2	R350M	Neutral	0.494
BRCA1	P38398-1.2	R350N	Pathogenic	0.566
BRCA1	P38398-1.2	R350P	Pathogenic	0.751
BRCA1	P38398-1.2	R350Q	Neutral	0.377
BRCA1	P38398-1.2	R350S	Pathogenic	0.756
BRCA1	P38398-1.2	R350T	Pathogenic	0.664
BRCA1	P38398-1.2	R350V	Pathogenic	0.755
BRCA1	P38398-1.2	R350W	Pathogenic	0.618
BRCA1	P38398-1.2	R350Y	Neutral	0.492
BRCA1	P38398-1.2	K351A	Neutral	0.104
BRCA1	P38398-1.2	K351C	Neutral	0.135
BRCA1	P38398-1.2	K351D	Neutral	0.065
BRCA1	P38398-1.2	K351E	Neutral	0.022
BRCA1	P38398-1.2	K351F	Neutral	0.049
BRCA1	P38398-1.2	K351G	Neutral	0.205
BRCA1	P38398-1.2	K351H	Neutral	0.036
BRCA1	P38398-1.2	K351I	Neutral	0.062
BRCA1	P38398-1.2	K351L	Neutral	0.044
BRCA1	P38398-1.2	K351M	Neutral	0.031
BRCA1	P38398-1.2	K351N	Neutral	0.041
BRCA1	P38398-1.2	K351P	Neutral	0.065
BRCA1	P38398-1.2	K351Q	Neutral	0.02
BRCA1	P38398-1.2	K351R	Neutral	0.012
BRCA1	P38398-1.2	K351S	Neutral	0.067
BRCA1	P38398-1.2	K351T	Neutral	0.061
BRCA1	P38398-1.2	K351V	Neutral	0.066
BRCA1	P38398-1.2	K351W	Neutral	0.087
BRCA1	P38398-1.2	K351Y	Neutral	0.04
BRCA1	P38398-1.2	E352A	Neutral	0.417
BRCA1	P38398-1.2	E352C	Pathogenic	0.58
BRCA1	P38398-1.2	E352D	Neutral	0.125
BRCA1	P38398-1.2	E352F	Pathogenic	0.502
BRCA1	P38398-1.2	E352G	Pathogenic	0.612
BRCA1	P38398-1.2	E352H	Neutral	0.193
BRCA1	P38398-1.2	E352I	Neutral	0.442
BRCA1	P38398-1.2	E352K	Neutral	0.197
BRCA1	P38398-1.2	E352L	Neutral	0.442
BRCA1	P38398-1.2	E352M	Neutral	0.357
BRCA1	P38398-1.2	E352N	Neutral	0.21
BRCA1	P38398-1.2	E352P	Neutral	0.299
BRCA1	P38398-1.2	E352Q	Neutral	0.096
BRCA1	P38398-1.2	E352R	Neutral	0.32
BRCA1	P38398-1.2	E352S	Neutral	0.305
BRCA1	P38398-1.2	E352T	Neutral	0.287
BRCA1	P38398-1.2	E352V	Neutral	0.303
BRCA1	P38398-1.2	E352W	Pathogenic	0.651
BRCA1	P38398-1.2	E352Y	Neutral	0.449
BRCA1	P38398-1.2	W353A	Neutral	0.127
BRCA1	P38398-1.2	W353C	Neutral	0.063
BRCA1	P38398-1.2	W353D	Neutral	0.107
BRCA1	P38398-1.2	W353E	Neutral	0.053
BRCA1	P38398-1.2	W353F	Neutral	0.008
BRCA1	P38398-1.2	W353G	Neutral	0.133
BRCA1	P38398-1.2	W353H	Neutral	0.031
BRCA1	P38398-1.2	W353I	Neutral	0.041
BRCA1	P38398-1.2	W353K	Neutral	0.03
BRCA1	P38398-1.2	W353L	Neutral	0.028
BRCA1	P38398-1.2	W353M	Neutral	0.02
BRCA1	P38398-1.2	W353N	Neutral	0.098
BRCA1	P38398-1.2	W353P	Neutral	0.112
BRCA1	P38398-1.2	W353Q	Neutral	0.034
BRCA1	P38398-1.2	W353R	Neutral	0.023
BRCA1	P38398-1.2	W353S	Neutral	0.112
BRCA1	P38398-1.2	W353T	Neutral	0.054
BRCA1	P38398-1.2	W353V	Neutral	0.06
BRCA1	P38398-1.2	W353Y	Neutral	0.005
BRCA1	P38398-1.2	N354A	Neutral	0.007
BRCA1	P38398-1.2	N354C	Neutral	0.006
BRCA1	P38398-1.2	N354D	Neutral	0.001
BRCA1	P38398-1.2	N354E	Neutral	0.002
BRCA1	P38398-1.2	N354F	Neutral	0.012
BRCA1	P38398-1.2	N354G	Neutral	0.005
BRCA1	P38398-1.2	N354H	Neutral	0.002
BRCA1	P38398-1.2	N354I	Neutral	0.009
BRCA1	P38398-1.2	N354K	Neutral	0.004
BRCA1	P38398-1.2	N354L	Neutral	0.009
BRCA1	P38398-1.2	N354M	Neutral	0.007
BRCA1	P38398-1.2	N354P	Neutral	0.004
BRCA1	P38398-1.2	N354Q	Neutral	0.003
BRCA1	P38398-1.2	N354R	Neutral	0.006
BRCA1	P38398-1.2	N354S	Neutral	0.002
BRCA1	P38398-1.2	N354T	Neutral	0.002
BRCA1	P38398-1.2	N354V	Neutral	0.006
BRCA1	P38398-1.2	N354W	Neutral	0.031
BRCA1	P38398-1.2	N354Y	Neutral	0.01
BRCA1	P38398-1.2	K355A	Neutral	0.233
BRCA1	P38398-1.2	K355C	Neutral	0.29
BRCA1	P38398-1.2	K355D	Neutral	0.154
BRCA1	P38398-1.2	K355E	Neutral	0.056
BRCA1	P38398-1.2	K355F	Neutral	0.119
BRCA1	P38398-1.2	K355G	Neutral	0.402
BRCA1	P38398-1.2	K355H	Neutral	0.09
BRCA1	P38398-1.2	K355I	Neutral	0.147
BRCA1	P38398-1.2	K355L	Neutral	0.107
BRCA1	P38398-1.2	K355M	Neutral	0.078
BRCA1	P38398-1.2	K355N	Neutral	0.102
BRCA1	P38398-1.2	K355P	Neutral	0.153
BRCA1	P38398-1.2	K355Q	Neutral	0.05
BRCA1	P38398-1.2	K355R	Neutral	0.03
BRCA1	P38398-1.2	K355S	Neutral	0.157
BRCA1	P38398-1.2	K355T	Neutral	0.146
BRCA1	P38398-1.2	K355V	Neutral	0.156
BRCA1	P38398-1.2	K355W	Neutral	0.2
BRCA1	P38398-1.2	K355Y	Neutral	0.098
BRCA1	P38398-1.2	Q356A	Pathogenic	0.844
BRCA1	P38398-1.2	Q356C	Pathogenic	0.879
BRCA1	P38398-1.2	Q356D	Pathogenic	0.688
BRCA1	P38398-1.2	Q356E	Neutral	0.417
BRCA1	P38398-1.2	Q356F	Pathogenic	0.859
BRCA1	P38398-1.2	Q356G	Pathogenic	0.923
BRCA1	P38398-1.2	Q356H	Pathogenic	0.592
BRCA1	P38398-1.2	Q356I	Pathogenic	0.827
BRCA1	P38398-1.2	Q356K	Pathogenic	0.593
BRCA1	P38398-1.2	Q356L	Pathogenic	0.769
BRCA1	P38398-1.2	Q356M	Pathogenic	0.619
BRCA1	P38398-1.2	Q356N	Pathogenic	0.664
BRCA1	P38398-1.2	Q356P	Pathogenic	0.763
BRCA1	P38398-1.2	Q356R	Pathogenic	0.661
BRCA1	P38398-1.2	Q356S	Pathogenic	0.768
BRCA1	P38398-1.2	Q356T	Pathogenic	0.753
BRCA1	P38398-1.2	Q356V	Pathogenic	0.767
BRCA1	P38398-1.2	Q356W	Pathogenic	0.887
BRCA1	P38398-1.2	Q356Y	Pathogenic	0.774
BRCA1	P38398-1.2	K357A	Pathogenic	0.74
BRCA1	P38398-1.2	K357C	Pathogenic	0.792
BRCA1	P38398-1.2	K357D	Pathogenic	0.63
BRCA1	P38398-1.2	K357E	Neutral	0.355
BRCA1	P38398-1.2	K357F	Pathogenic	0.558
BRCA1	P38398-1.2	K357G	Pathogenic	0.863
BRCA1	P38398-1.2	K357H	Neutral	0.479
BRCA1	P38398-1.2	K357I	Pathogenic	0.617
BRCA1	P38398-1.2	K357L	Pathogenic	0.529
BRCA1	P38398-1.2	K357M	Neutral	0.441
BRCA1	P38398-1.2	K357N	Pathogenic	0.514
BRCA1	P38398-1.2	K357P	Pathogenic	0.629
BRCA1	P38398-1.2	K357Q	Neutral	0.328
BRCA1	P38398-1.2	K357R	Neutral	0.224
BRCA1	P38398-1.2	K357S	Pathogenic	0.635
BRCA1	P38398-1.2	K357T	Pathogenic	0.615
BRCA1	P38398-1.2	K357V	Pathogenic	0.634
BRCA1	P38398-1.2	K357W	Pathogenic	0.7
BRCA1	P38398-1.2	K357Y	Pathogenic	0.505
BRCA1	P38398-1.2	L358A	Neutral	0.042
BRCA1	P38398-1.2	L358C	Neutral	0.028
BRCA1	P38398-1.2	L358D	Neutral	0.07
BRCA1	P38398-1.2	L358E	Neutral	0.034
BRCA1	P38398-1.2	L358F	Neutral	0.011
BRCA1	P38398-1.2	L358G	Neutral	0.166
BRCA1	P38398-1.2	L358H	Neutral	0.028
BRCA1	P38398-1.2	L358I	Neutral	0.004
BRCA1	P38398-1.2	L358K	Neutral	0.022
BRCA1	P38398-1.2	L358M	Neutral	0.004
BRCA1	P38398-1.2	L358N	Neutral	0.045
BRCA1	P38398-1.2	L358P	Neutral	0.052
BRCA1	P38398-1.2	L358Q	Neutral	0.022
BRCA1	P38398-1.2	L358R	Neutral	0.029
BRCA1	P38398-1.2	L358S	Neutral	0.052
BRCA1	P38398-1.2	L358T	Neutral	0.024
BRCA1	P38398-1.2	L358V	Neutral	0.009
BRCA1	P38398-1.2	L358W	Neutral	0.041
BRCA1	P38398-1.2	L358Y	Neutral	0.018
BRCA1	P38398-1.2	P359A	Neutral	0.076
BRCA1	P38398-1.2	P359C	Neutral	0.101
BRCA1	P38398-1.2	P359D	Neutral	0.047
BRCA1	P38398-1.2	P359E	Neutral	0.069
BRCA1	P38398-1.2	P359F	Neutral	0.283
BRCA1	P38398-1.2	P359G	Neutral	0.152
BRCA1	P38398-1.2	P359H	Neutral	0.117
BRCA1	P38398-1.2	P359I	Neutral	0.177
BRCA1	P38398-1.2	P359K	Neutral	0.116
BRCA1	P38398-1.2	P359L	Neutral	0.177
BRCA1	P38398-1.2	P359M	Neutral	0.131
BRCA1	P38398-1.2	P359N	Neutral	0.074
BRCA1	P38398-1.2	P359Q	Neutral	0.077
BRCA1	P38398-1.2	P359R	Neutral	0.201
BRCA1	P38398-1.2	P359S	Neutral	0.067
BRCA1	P38398-1.2	P359T	Neutral	0.05
BRCA1	P38398-1.2	P359V	Neutral	0.09
BRCA1	P38398-1.2	P359W	Neutral	0.422
BRCA1	P38398-1.2	P359Y	Neutral	0.242
BRCA1	P38398-1.2	C360A	Neutral	0.132
BRCA1	P38398-1.2	C360D	Neutral	0.245
BRCA1	P38398-1.2	C360E	Neutral	0.411
BRCA1	P38398-1.2	C360F	Neutral	0.379
BRCA1	P38398-1.2	C360G	Neutral	0.407
BRCA1	P38398-1.2	C360H	Neutral	0.376
BRCA1	P38398-1.2	C360I	Neutral	0.249
BRCA1	P38398-1.2	C360K	Neutral	0.462
BRCA1	P38398-1.2	C360L	Neutral	0.25
BRCA1	P38398-1.2	C360M	Neutral	0.251
BRCA1	P38398-1.2	C360N	Neutral	0.267
BRCA1	P38398-1.2	C360P	Neutral	0.246
BRCA1	P38398-1.2	C360Q	Neutral	0.354
BRCA1	P38398-1.2	C360R	Pathogenic	0.534
BRCA1	P38398-1.2	C360S	Neutral	0.16
BRCA1	P38398-1.2	C360T	Neutral	0.143
BRCA1	P38398-1.2	C360V	Neutral	0.181
BRCA1	P38398-1.2	C360W	Pathogenic	0.53
BRCA1	P38398-1.2	C360Y	Neutral	0.415
BRCA1	P38398-1.2	S361A	Neutral	0.376
BRCA1	P38398-1.2	S361C	Pathogenic	0.59
BRCA1	P38398-1.2	S361D	Pathogenic	0.529
BRCA1	P38398-1.2	S361E	Pathogenic	0.627
BRCA1	P38398-1.2	S361F	Pathogenic	0.858
BRCA1	P38398-1.2	S361G	Pathogenic	0.571
BRCA1	P38398-1.2	S361H	Pathogenic	0.749
BRCA1	P38398-1.2	S361I	Pathogenic	0.826
BRCA1	P38398-1.2	S361K	Pathogenic	0.748
BRCA1	P38398-1.2	S361L	Pathogenic	0.826
BRCA1	P38398-1.2	S361M	Pathogenic	0.769
BRCA1	P38398-1.2	S361N	Neutral	0.467
BRCA1	P38398-1.2	S361P	Pathogenic	0.613
BRCA1	P38398-1.2	S361Q	Pathogenic	0.654
BRCA1	P38398-1.2	S361R	Pathogenic	0.851
BRCA1	P38398-1.2	S361T	Neutral	0.452
BRCA1	P38398-1.2	S361V	Pathogenic	0.759
BRCA1	P38398-1.2	S361W	Pathogenic	0.941
BRCA1	P38398-1.2	S361Y	Pathogenic	0.876
BRCA1	P38398-1.2	E362A	Neutral	0.116
BRCA1	P38398-1.2	E362C	Neutral	0.202
BRCA1	P38398-1.2	E362D	Neutral	0.026
BRCA1	P38398-1.2	E362F	Neutral	0.156
BRCA1	P38398-1.2	E362G	Neutral	0.225
BRCA1	P38398-1.2	E362H	Neutral	0.042
BRCA1	P38398-1.2	E362I	Neutral	0.127
BRCA1	P38398-1.2	E362K	Neutral	0.043
BRCA1	P38398-1.2	E362L	Neutral	0.127
BRCA1	P38398-1.2	E362M	Neutral	0.093
BRCA1	P38398-1.2	E362N	Neutral	0.047
BRCA1	P38398-1.2	E362P	Neutral	0.073
BRCA1	P38398-1.2	E362Q	Neutral	0.019
BRCA1	P38398-1.2	E362R	Neutral	0.08
BRCA1	P38398-1.2	E362S	Neutral	0.075
BRCA1	P38398-1.2	E362T	Neutral	0.069
BRCA1	P38398-1.2	E362V	Neutral	0.074
BRCA1	P38398-1.2	E362W	Neutral	0.255
BRCA1	P38398-1.2	E362Y	Neutral	0.13
BRCA1	P38398-1.2	N363A	Neutral	0.002
BRCA1	P38398-1.2	N363C	Neutral	0.002
BRCA1	P38398-1.2	N363D	Neutral	0.0
BRCA1	P38398-1.2	N363E	Neutral	0.001
BRCA1	P38398-1.2	N363F	Neutral	0.003
BRCA1	P38398-1.2	N363G	Neutral	0.001
BRCA1	P38398-1.2	N363H	Neutral	0.001
BRCA1	P38398-1.2	N363I	Neutral	0.002
BRCA1	P38398-1.2	N363K	Neutral	0.001
BRCA1	P38398-1.2	N363L	Neutral	0.002
BRCA1	P38398-1.2	N363M	Neutral	0.002
BRCA1	P38398-1.2	N363P	Neutral	0.001
BRCA1	P38398-1.2	N363Q	Neutral	0.001
BRCA1	P38398-1.2	N363R	Neutral	0.001
BRCA1	P38398-1.2	N363S	Neutral	0.001
BRCA1	P38398-1.2	N363T	Neutral	0.0
BRCA1	P38398-1.2	N363V	Neutral	0.002
BRCA1	P38398-1.2	N363W	Neutral	0.008
BRCA1	P38398-1.2	N363Y	Neutral	0.002
BRCA1	P38398-1.2	P364A	Neutral	0.168
BRCA1	P38398-1.2	P364C	Neutral	0.216
BRCA1	P38398-1.2	P364D	Neutral	0.108
BRCA1	P38398-1.2	P364E	Neutral	0.154
BRCA1	P38398-1.2	P364F	Neutral	0.492
BRCA1	P38398-1.2	P364G	Neutral	0.306
BRCA1	P38398-1.2	P364H	Neutral	0.245
BRCA1	P38398-1.2	P364I	Neutral	0.345
BRCA1	P38398-1.2	P364K	Neutral	0.243
BRCA1	P38398-1.2	P364L	Neutral	0.346
BRCA1	P38398-1.2	P364M	Neutral	0.27
BRCA1	P38398-1.2	P364N	Neutral	0.164
BRCA1	P38398-1.2	P364Q	Neutral	0.17
BRCA1	P38398-1.2	P364R	Neutral	0.382
BRCA1	P38398-1.2	P364S	Neutral	0.149
BRCA1	P38398-1.2	P364T	Neutral	0.115
BRCA1	P38398-1.2	P364V	Neutral	0.196
BRCA1	P38398-1.2	P364W	Pathogenic	0.642
BRCA1	P38398-1.2	P364Y	Neutral	0.439
BRCA1	P38398-1.2	R365A	Pathogenic	0.818
BRCA1	P38398-1.2	R365C	Pathogenic	0.858
BRCA1	P38398-1.2	R365D	Pathogenic	0.795
BRCA1	P38398-1.2	R365E	Pathogenic	0.556
BRCA1	P38398-1.2	R365F	Pathogenic	0.666
BRCA1	P38398-1.2	R365G	Pathogenic	0.908
BRCA1	P38398-1.2	R365H	Pathogenic	0.502
BRCA1	P38398-1.2	R365I	Pathogenic	0.718
BRCA1	P38398-1.2	R365K	Neutral	0.254
BRCA1	P38398-1.2	R365L	Pathogenic	0.639
BRCA1	P38398-1.2	R365M	Pathogenic	0.554
BRCA1	P38398-1.2	R365N	Pathogenic	0.625
BRCA1	P38398-1.2	R365P	Pathogenic	0.794
BRCA1	P38398-1.2	R365Q	Neutral	0.435
BRCA1	P38398-1.2	R365S	Pathogenic	0.798
BRCA1	P38398-1.2	R365T	Pathogenic	0.716
BRCA1	P38398-1.2	R365V	Pathogenic	0.797
BRCA1	P38398-1.2	R365W	Pathogenic	0.674
BRCA1	P38398-1.2	R365Y	Pathogenic	0.552
BRCA1	P38398-1.2	D366A	Neutral	0.191
BRCA1	P38398-1.2	D366C	Neutral	0.18
BRCA1	P38398-1.2	D366E	Neutral	0.047
BRCA1	P38398-1.2	D366F	Neutral	0.34
BRCA1	P38398-1.2	D366G	Neutral	0.201
BRCA1	P38398-1.2	D366H	Neutral	0.15
BRCA1	P38398-1.2	D366I	Neutral	0.288
BRCA1	P38398-1.2	D366K	Neutral	0.207
BRCA1	P38398-1.2	D366L	Neutral	0.368
BRCA1	P38398-1.2	D366M	Neutral	0.29
BRCA1	P38398-1.2	D366N	Neutral	0.05
BRCA1	P38398-1.2	D366P	Neutral	0.089
BRCA1	P38398-1.2	D366Q	Neutral	0.101
BRCA1	P38398-1.2	D366R	Neutral	0.333
BRCA1	P38398-1.2	D366S	Neutral	0.091
BRCA1	P38398-1.2	D366T	Neutral	0.092
BRCA1	P38398-1.2	D366V	Neutral	0.211
BRCA1	P38398-1.2	D366W	Pathogenic	0.578
BRCA1	P38398-1.2	D366Y	Neutral	0.374
BRCA1	P38398-1.2	T367A	Neutral	0.012
BRCA1	P38398-1.2	T367C	Neutral	0.011
BRCA1	P38398-1.2	T367D	Neutral	0.01
BRCA1	P38398-1.2	T367E	Neutral	0.013
BRCA1	P38398-1.2	T367F	Neutral	0.033
BRCA1	P38398-1.2	T367G	Neutral	0.036
BRCA1	P38398-1.2	T367H	Neutral	0.023
BRCA1	P38398-1.2	T367I	Neutral	0.018
BRCA1	P38398-1.2	T367K	Neutral	0.023
BRCA1	P38398-1.2	T367L	Neutral	0.018
BRCA1	P38398-1.2	T367M	Neutral	0.018
BRCA1	P38398-1.2	T367N	Neutral	0.007
BRCA1	P38398-1.2	T367P	Neutral	0.01
BRCA1	P38398-1.2	T367Q	Neutral	0.015
BRCA1	P38398-1.2	T367R	Neutral	0.03
BRCA1	P38398-1.2	T367S	Neutral	0.007
BRCA1	P38398-1.2	T367V	Neutral	0.008
BRCA1	P38398-1.2	T367W	Neutral	0.059
BRCA1	P38398-1.2	T367Y	Neutral	0.038
BRCA1	P38398-1.2	E368A	Neutral	0.191
BRCA1	P38398-1.2	E368C	Neutral	0.314
BRCA1	P38398-1.2	E368D	Neutral	0.045
BRCA1	P38398-1.2	E368F	Neutral	0.25
BRCA1	P38398-1.2	E368G	Neutral	0.343
BRCA1	P38398-1.2	E368H	Neutral	0.073
BRCA1	P38398-1.2	E368I	Neutral	0.207
BRCA1	P38398-1.2	E368K	Neutral	0.075
BRCA1	P38398-1.2	E368L	Neutral	0.208
BRCA1	P38398-1.2	E368M	Neutral	0.155
BRCA1	P38398-1.2	E368N	Neutral	0.081
BRCA1	P38398-1.2	E368P	Neutral	0.124
BRCA1	P38398-1.2	E368Q	Neutral	0.034
BRCA1	P38398-1.2	E368R	Neutral	0.135
BRCA1	P38398-1.2	E368S	Neutral	0.127
BRCA1	P38398-1.2	E368T	Neutral	0.117
BRCA1	P38398-1.2	E368V	Neutral	0.126
BRCA1	P38398-1.2	E368W	Neutral	0.381
BRCA1	P38398-1.2	E368Y	Neutral	0.212
BRCA1	P38398-1.2	D369A	Pathogenic	0.878
BRCA1	P38398-1.2	D369C	Pathogenic	0.87
BRCA1	P38398-1.2	D369E	Pathogenic	0.598
BRCA1	P38398-1.2	D369F	Pathogenic	0.94
BRCA1	P38398-1.2	D369G	Pathogenic	0.884
BRCA1	P38398-1.2	D369H	Pathogenic	0.842
BRCA1	P38398-1.2	D369I	Pathogenic	0.925
BRCA1	P38398-1.2	D369K	Pathogenic	0.888
BRCA1	P38398-1.2	D369L	Pathogenic	0.946
BRCA1	P38398-1.2	D369M	Pathogenic	0.925
BRCA1	P38398-1.2	D369N	Pathogenic	0.616
BRCA1	P38398-1.2	D369P	Pathogenic	0.748
BRCA1	P38398-1.2	D369Q	Pathogenic	0.774
BRCA1	P38398-1.2	D369R	Pathogenic	0.938
BRCA1	P38398-1.2	D369S	Pathogenic	0.753
BRCA1	P38398-1.2	D369T	Pathogenic	0.754
BRCA1	P38398-1.2	D369V	Pathogenic	0.89
BRCA1	P38398-1.2	D369W	Pathogenic	0.977
BRCA1	P38398-1.2	D369Y	Pathogenic	0.948
BRCA1	P38398-1.2	V370A	Neutral	0.131
BRCA1	P38398-1.2	V370C	Neutral	0.125
BRCA1	P38398-1.2	V370D	Neutral	0.205
BRCA1	P38398-1.2	V370E	Neutral	0.125
BRCA1	P38398-1.2	V370F	Neutral	0.154
BRCA1	P38398-1.2	V370G	Neutral	0.404
BRCA1	P38398-1.2	V370H	Neutral	0.204
BRCA1	P38398-1.2	V370I	Neutral	0.032
BRCA1	P38398-1.2	V370K	Neutral	0.202
BRCA1	P38398-1.2	V370L	Neutral	0.065
BRCA1	P38398-1.2	V370M	Neutral	0.065
BRCA1	P38398-1.2	V370N	Neutral	0.188
BRCA1	P38398-1.2	V370P	Neutral	0.158
BRCA1	P38398-1.2	V370Q	Neutral	0.139
BRCA1	P38398-1.2	V370R	Neutral	0.328
BRCA1	P38398-1.2	V370S	Neutral	0.213
BRCA1	P38398-1.2	V370T	Neutral	0.078
BRCA1	P38398-1.2	V370W	Neutral	0.41
BRCA1	P38398-1.2	V370Y	Neutral	0.173
BRCA1	P38398-1.2	P371A	Pathogenic	0.546
BRCA1	P38398-1.2	P371C	Pathogenic	0.621
BRCA1	P38398-1.2	P371D	Neutral	0.419
BRCA1	P38398-1.2	P371E	Pathogenic	0.519
BRCA1	P38398-1.2	P371F	Pathogenic	0.852
BRCA1	P38398-1.2	P371G	Pathogenic	0.724
BRCA1	P38398-1.2	P371H	Pathogenic	0.658
BRCA1	P38398-1.2	P371I	Pathogenic	0.758
BRCA1	P38398-1.2	P371K	Pathogenic	0.656
BRCA1	P38398-1.2	P371L	Pathogenic	0.759
BRCA1	P38398-1.2	P371M	Pathogenic	0.688
BRCA1	P38398-1.2	P371N	Pathogenic	0.538
BRCA1	P38398-1.2	P371Q	Pathogenic	0.549
BRCA1	P38398-1.2	P371R	Pathogenic	0.786
BRCA1	P38398-1.2	P371S	Pathogenic	0.511
BRCA1	P38398-1.2	P371T	Neutral	0.435
BRCA1	P38398-1.2	P371V	Pathogenic	0.591
BRCA1	P38398-1.2	P371W	Pathogenic	0.914
BRCA1	P38398-1.2	P371Y	Pathogenic	0.823
BRCA1	P38398-1.2	W372A	Pathogenic	0.999
BRCA1	P38398-1.2	W372C	Pathogenic	0.997
BRCA1	P38398-1.2	W372D	Pathogenic	0.998
BRCA1	P38398-1.2	W372E	Pathogenic	0.996
BRCA1	P38398-1.2	W372F	Pathogenic	0.973
BRCA1	P38398-1.2	W372G	Pathogenic	0.999
BRCA1	P38398-1.2	W372H	Pathogenic	0.993
BRCA1	P38398-1.2	W372I	Pathogenic	0.995
BRCA1	P38398-1.2	W372K	Pathogenic	0.993
BRCA1	P38398-1.2	W372L	Pathogenic	0.993
BRCA1	P38398-1.2	W372M	Pathogenic	0.99
BRCA1	P38398-1.2	W372N	Pathogenic	0.998
BRCA1	P38398-1.2	W372P	Pathogenic	0.998
BRCA1	P38398-1.2	W372Q	Pathogenic	0.994
BRCA1	P38398-1.2	W372R	Pathogenic	0.991
BRCA1	P38398-1.2	W372S	Pathogenic	0.998
BRCA1	P38398-1.2	W372T	Pathogenic	0.996
BRCA1	P38398-1.2	W372V	Pathogenic	0.997
BRCA1	P38398-1.2	W372Y	Pathogenic	0.956
BRCA1	P38398-1.2	I373A	Neutral	0.464
BRCA1	P38398-1.2	I373C	Neutral	0.365
BRCA1	P38398-1.2	I373D	Pathogenic	0.507
BRCA1	P38398-1.2	I373E	Neutral	0.409
BRCA1	P38398-1.2	I373F	Neutral	0.182
BRCA1	P38398-1.2	I373G	Pathogenic	0.796
BRCA1	P38398-1.2	I373H	Neutral	0.365
BRCA1	P38398-1.2	I373K	Neutral	0.386
BRCA1	P38398-1.2	I373L	Neutral	0.078
BRCA1	P38398-1.2	I373M	Neutral	0.107
BRCA1	P38398-1.2	I373N	Neutral	0.48
BRCA1	P38398-1.2	I373P	Pathogenic	0.52
BRCA1	P38398-1.2	I373Q	Neutral	0.384
BRCA1	P38398-1.2	I373R	Neutral	0.456
BRCA1	P38398-1.2	I373S	Pathogenic	0.52
BRCA1	P38398-1.2	I373T	Neutral	0.327
BRCA1	P38398-1.2	I373V	Neutral	0.081
BRCA1	P38398-1.2	I373W	Pathogenic	0.551
BRCA1	P38398-1.2	I373Y	Neutral	0.265
BRCA1	P38398-1.2	T374A	Pathogenic	0.892
BRCA1	P38398-1.2	T374C	Pathogenic	0.885
BRCA1	P38398-1.2	T374D	Pathogenic	0.873
BRCA1	P38398-1.2	T374E	Pathogenic	0.904
BRCA1	P38398-1.2	T374F	Pathogenic	0.96
BRCA1	P38398-1.2	T374G	Pathogenic	0.963
BRCA1	P38398-1.2	T374H	Pathogenic	0.944
BRCA1	P38398-1.2	T374I	Pathogenic	0.928
BRCA1	P38398-1.2	T374K	Pathogenic	0.943
BRCA1	P38398-1.2	T374L	Pathogenic	0.929
BRCA1	P38398-1.2	T374M	Pathogenic	0.929
BRCA1	P38398-1.2	T374N	Pathogenic	0.831
BRCA1	P38398-1.2	T374P	Pathogenic	0.877
BRCA1	P38398-1.2	T374Q	Pathogenic	0.914
BRCA1	P38398-1.2	T374R	Pathogenic	0.957
BRCA1	P38398-1.2	T374S	Pathogenic	0.834
BRCA1	P38398-1.2	T374V	Pathogenic	0.857
BRCA1	P38398-1.2	T374W	Pathogenic	0.978
BRCA1	P38398-1.2	T374Y	Pathogenic	0.965
BRCA1	P38398-1.2	L375A	Pathogenic	0.661
BRCA1	P38398-1.2	L375C	Pathogenic	0.564
BRCA1	P38398-1.2	L375D	Pathogenic	0.77
BRCA1	P38398-1.2	L375E	Pathogenic	0.61
BRCA1	P38398-1.2	L375F	Neutral	0.334
BRCA1	P38398-1.2	L375G	Pathogenic	0.898
BRCA1	P38398-1.2	L375H	Pathogenic	0.565
BRCA1	P38398-1.2	L375I	Neutral	0.159
BRCA1	P38398-1.2	L375K	Neutral	0.496
BRCA1	P38398-1.2	L375M	Neutral	0.158
BRCA1	P38398-1.2	L375N	Pathogenic	0.676
BRCA1	P38398-1.2	L375P	Pathogenic	0.71
BRCA1	P38398-1.2	L375Q	Neutral	0.495
BRCA1	P38398-1.2	L375R	Pathogenic	0.568
BRCA1	P38398-1.2	L375S	Pathogenic	0.709
BRCA1	P38398-1.2	L375T	Pathogenic	0.522
BRCA1	P38398-1.2	L375V	Neutral	0.292
BRCA1	P38398-1.2	L375W	Pathogenic	0.657
BRCA1	P38398-1.2	L375Y	Neutral	0.448
BRCA1	P38398-1.2	N376A	Pathogenic	0.919
BRCA1	P38398-1.2	N376C	Pathogenic	0.914
BRCA1	P38398-1.2	N376D	Pathogenic	0.694
BRCA1	P38398-1.2	N376E	Pathogenic	0.796
BRCA1	P38398-1.2	N376F	Pathogenic	0.952
BRCA1	P38398-1.2	N376G	Pathogenic	0.894
BRCA1	P38398-1.2	N376H	Pathogenic	0.766
BRCA1	P38398-1.2	N376I	Pathogenic	0.939
BRCA1	P38398-1.2	N376K	Pathogenic	0.874
BRCA1	P38398-1.2	N376L	Pathogenic	0.94
BRCA1	P38398-1.2	N376M	Pathogenic	0.916
BRCA1	P38398-1.2	N376P	Pathogenic	0.871
BRCA1	P38398-1.2	N376Q	Pathogenic	0.813
BRCA1	P38398-1.2	N376R	Pathogenic	0.902
BRCA1	P38398-1.2	N376S	Pathogenic	0.77
BRCA1	P38398-1.2	N376T	Pathogenic	0.755
BRCA1	P38398-1.2	N376V	Pathogenic	0.911
BRCA1	P38398-1.2	N376W	Pathogenic	0.981
BRCA1	P38398-1.2	N376Y	Pathogenic	0.941
BRCA1	P38398-1.2	S377A	Pathogenic	0.81
BRCA1	P38398-1.2	S377C	Pathogenic	0.911
BRCA1	P38398-1.2	S377D	Pathogenic	0.888
BRCA1	P38398-1.2	S377E	Pathogenic	0.922
BRCA1	P38398-1.2	S377F	Pathogenic	0.977
BRCA1	P38398-1.2	S377G	Pathogenic	0.904
BRCA1	P38398-1.2	S377H	Pathogenic	0.955
BRCA1	P38398-1.2	S377I	Pathogenic	0.971
BRCA1	P38398-1.2	S377K	Pathogenic	0.955
BRCA1	P38398-1.2	S377L	Pathogenic	0.971
BRCA1	P38398-1.2	S377M	Pathogenic	0.959
BRCA1	P38398-1.2	S377N	Pathogenic	0.861
BRCA1	P38398-1.2	S377P	Pathogenic	0.918
BRCA1	P38398-1.2	S377Q	Pathogenic	0.931
BRCA1	P38398-1.2	S377R	Pathogenic	0.976
BRCA1	P38398-1.2	S377T	Pathogenic	0.854
BRCA1	P38398-1.2	S377V	Pathogenic	0.957
BRCA1	P38398-1.2	S377W	Pathogenic	0.991
BRCA1	P38398-1.2	S377Y	Pathogenic	0.98
BRCA1	P38398-1.2	S378A	Pathogenic	0.883
BRCA1	P38398-1.2	S378C	Pathogenic	0.947
BRCA1	P38398-1.2	S378D	Pathogenic	0.934
BRCA1	P38398-1.2	S378E	Pathogenic	0.955
BRCA1	P38398-1.2	S378F	Pathogenic	0.987
BRCA1	P38398-1.2	S378G	Pathogenic	0.943
BRCA1	P38398-1.2	S378H	Pathogenic	0.974
BRCA1	P38398-1.2	S378I	Pathogenic	0.983
BRCA1	P38398-1.2	S378K	Pathogenic	0.974
BRCA1	P38398-1.2	S378L	Pathogenic	0.983
BRCA1	P38398-1.2	S378M	Pathogenic	0.977
BRCA1	P38398-1.2	S378N	Pathogenic	0.916
BRCA1	P38398-1.2	S378P	Pathogenic	0.952
BRCA1	P38398-1.2	S378Q	Pathogenic	0.959
BRCA1	P38398-1.2	S378R	Pathogenic	0.986
BRCA1	P38398-1.2	S378T	Pathogenic	0.911
BRCA1	P38398-1.2	S378V	Pathogenic	0.975
BRCA1	P38398-1.2	S378W	Pathogenic	0.995
BRCA1	P38398-1.2	S378Y	Pathogenic	0.989
BRCA1	P38398-1.2	I379A	Pathogenic	0.992
BRCA1	P38398-1.2	I379C	Pathogenic	0.988
BRCA1	P38398-1.2	I379D	Pathogenic	0.994
BRCA1	P38398-1.2	I379E	Pathogenic	0.99
BRCA1	P38398-1.2	I379F	Pathogenic	0.971
BRCA1	P38398-1.2	I379G	Pathogenic	0.998
BRCA1	P38398-1.2	I379H	Pathogenic	0.988
BRCA1	P38398-1.2	I379K	Pathogenic	0.989
BRCA1	P38398-1.2	I379L	Pathogenic	0.926
BRCA1	P38398-1.2	I379M	Pathogenic	0.947
BRCA1	P38398-1.2	I379N	Pathogenic	0.993
BRCA1	P38398-1.2	I379P	Pathogenic	0.994
BRCA1	P38398-1.2	I379Q	Pathogenic	0.989
BRCA1	P38398-1.2	I379R	Pathogenic	0.992
BRCA1	P38398-1.2	I379S	Pathogenic	0.994
BRCA1	P38398-1.2	I379T	Pathogenic	0.986
BRCA1	P38398-1.2	I379V	Pathogenic	0.929
BRCA1	P38398-1.2	I379W	Pathogenic	0.995
BRCA1	P38398-1.2	I379Y	Pathogenic	0.982
BRCA1	P38398-1.2	Q380A	Pathogenic	0.962
BRCA1	P38398-1.2	Q380C	Pathogenic	0.971
BRCA1	P38398-1.2	Q380D	Pathogenic	0.912
BRCA1	P38398-1.2	Q380E	Pathogenic	0.771
BRCA1	P38398-1.2	Q380F	Pathogenic	0.966
BRCA1	P38398-1.2	Q380G	Pathogenic	0.982
BRCA1	P38398-1.2	Q380H	Pathogenic	0.872
BRCA1	P38398-1.2	Q380I	Pathogenic	0.957
BRCA1	P38398-1.2	Q380K	Pathogenic	0.873
BRCA1	P38398-1.2	Q380L	Pathogenic	0.94
BRCA1	P38398-1.2	Q380M	Pathogenic	0.884
BRCA1	P38398-1.2	Q380N	Pathogenic	0.903
BRCA1	P38398-1.2	Q380P	Pathogenic	0.938
BRCA1	P38398-1.2	Q380R	Pathogenic	0.901
BRCA1	P38398-1.2	Q380S	Pathogenic	0.94
BRCA1	P38398-1.2	Q380T	Pathogenic	0.935
BRCA1	P38398-1.2	Q380V	Pathogenic	0.939
BRCA1	P38398-1.2	Q380W	Pathogenic	0.974
BRCA1	P38398-1.2	Q380Y	Pathogenic	0.941
BRCA1	P38398-1.2	K381A	Pathogenic	0.994
BRCA1	P38398-1.2	K381C	Pathogenic	0.995
BRCA1	P38398-1.2	K381D	Pathogenic	0.989
BRCA1	P38398-1.2	K381E	Pathogenic	0.968
BRCA1	P38398-1.2	K381F	Pathogenic	0.986
BRCA1	P38398-1.2	K381G	Pathogenic	0.997
BRCA1	P38398-1.2	K381H	Pathogenic	0.981
BRCA1	P38398-1.2	K381I	Pathogenic	0.989
BRCA1	P38398-1.2	K381L	Pathogenic	0.984
BRCA1	P38398-1.2	K381M	Pathogenic	0.977
BRCA1	P38398-1.2	K381N	Pathogenic	0.983
BRCA1	P38398-1.2	K381P	Pathogenic	0.989
BRCA1	P38398-1.2	K381Q	Pathogenic	0.964
BRCA1	P38398-1.2	K381R	Pathogenic	0.94
BRCA1	P38398-1.2	K381S	Pathogenic	0.99
BRCA1	P38398-1.2	K381T	Pathogenic	0.989
BRCA1	P38398-1.2	K381V	Pathogenic	0.99
BRCA1	P38398-1.2	K381W	Pathogenic	0.992
BRCA1	P38398-1.2	K381Y	Pathogenic	0.982
BRCA1	P38398-1.2	V382A	Pathogenic	0.99
BRCA1	P38398-1.2	V382C	Pathogenic	0.99
BRCA1	P38398-1.2	V382D	Pathogenic	0.994
BRCA1	P38398-1.2	V382E	Pathogenic	0.99
BRCA1	P38398-1.2	V382F	Pathogenic	0.992
BRCA1	P38398-1.2	V382G	Pathogenic	0.998
BRCA1	P38398-1.2	V382H	Pathogenic	0.994
BRCA1	P38398-1.2	V382I	Pathogenic	0.956
BRCA1	P38398-1.2	V382K	Pathogenic	0.994
BRCA1	P38398-1.2	V382L	Pathogenic	0.978
BRCA1	P38398-1.2	V382M	Pathogenic	0.979
BRCA1	P38398-1.2	V382N	Pathogenic	0.993
BRCA1	P38398-1.2	V382P	Pathogenic	0.992
BRCA1	P38398-1.2	V382Q	Pathogenic	0.991
BRCA1	P38398-1.2	V382R	Pathogenic	0.997
BRCA1	P38398-1.2	V382S	Pathogenic	0.994
BRCA1	P38398-1.2	V382T	Pathogenic	0.982
BRCA1	P38398-1.2	V382W	Pathogenic	0.998
BRCA1	P38398-1.2	V382Y	Pathogenic	0.993
BRCA1	P38398-1.2	N383A	Pathogenic	0.992
BRCA1	P38398-1.2	N383C	Pathogenic	0.991
BRCA1	P38398-1.2	N383D	Pathogenic	0.96
BRCA1	P38398-1.2	N383E	Pathogenic	0.977
BRCA1	P38398-1.2	N383F	Pathogenic	0.995
BRCA1	P38398-1.2	N383G	Pathogenic	0.989
BRCA1	P38398-1.2	N383H	Pathogenic	0.972
BRCA1	P38398-1.2	N383I	Pathogenic	0.994
BRCA1	P38398-1.2	N383K	Pathogenic	0.987
BRCA1	P38398-1.2	N383L	Pathogenic	0.994
BRCA1	P38398-1.2	N383M	Pathogenic	0.992
BRCA1	P38398-1.2	N383P	Pathogenic	0.986
BRCA1	P38398-1.2	N383Q	Pathogenic	0.979
BRCA1	P38398-1.2	N383R	Pathogenic	0.99
BRCA1	P38398-1.2	N383S	Pathogenic	0.973
BRCA1	P38398-1.2	N383T	Pathogenic	0.971
BRCA1	P38398-1.2	N383V	Pathogenic	0.991
BRCA1	P38398-1.2	N383W	Pathogenic	0.998
BRCA1	P38398-1.2	N383Y	Pathogenic	0.994
BRCA1	P38398-1.2	E384A	Pathogenic	0.935
BRCA1	P38398-1.2	E384C	Pathogenic	0.965
BRCA1	P38398-1.2	E384D	Pathogenic	0.743
BRCA1	P38398-1.2	E384F	Pathogenic	0.953
BRCA1	P38398-1.2	E384G	Pathogenic	0.97
BRCA1	P38398-1.2	E384H	Pathogenic	0.829
BRCA1	P38398-1.2	E384I	Pathogenic	0.941
BRCA1	P38398-1.2	E384K	Pathogenic	0.832
BRCA1	P38398-1.2	E384L	Pathogenic	0.941
BRCA1	P38398-1.2	E384M	Pathogenic	0.918
BRCA1	P38398-1.2	E384N	Pathogenic	0.843
BRCA1	P38398-1.2	E384P	Pathogenic	0.896
BRCA1	P38398-1.2	E384Q	Pathogenic	0.683
BRCA1	P38398-1.2	E384R	Pathogenic	0.905
BRCA1	P38398-1.2	E384S	Pathogenic	0.898
BRCA1	P38398-1.2	E384T	Pathogenic	0.89
BRCA1	P38398-1.2	E384V	Pathogenic	0.898
BRCA1	P38398-1.2	E384W	Pathogenic	0.974
BRCA1	P38398-1.2	E384Y	Pathogenic	0.943
BRCA1	P38398-1.2	W385A	Pathogenic	1.0
BRCA1	P38398-1.2	W385C	Pathogenic	1.0
BRCA1	P38398-1.2	W385D	Pathogenic	1.0
BRCA1	P38398-1.2	W385E	Pathogenic	0.999
BRCA1	P38398-1.2	W385F	Pathogenic	0.996
BRCA1	P38398-1.2	W385G	Pathogenic	1.0
BRCA1	P38398-1.2	W385H	Pathogenic	0.999
BRCA1	P38398-1.2	W385I	Pathogenic	0.999
BRCA1	P38398-1.2	W385K	Pathogenic	0.999
BRCA1	P38398-1.2	W385L	Pathogenic	0.999
BRCA1	P38398-1.2	W385M	Pathogenic	0.998
BRCA1	P38398-1.2	W385N	Pathogenic	1.0
BRCA1	P38398-1.2	W385P	Pathogenic	1.0
BRCA1	P38398-1.2	W385Q	Pathogenic	0.999
BRCA1	P38398-1.2	W385R	Pathogenic	0.999
BRCA1	P38398-1.2	W385S	Pathogenic	1.0
BRCA1	P38398-1.2	W385T	Pathogenic	0.999
BRCA1	P38398-1.2	W385V	Pathogenic	0.999
BRCA1	P38398-1.2	W385Y	Pathogenic	0.993
BRCA1	P38398-1.2	F386A	Pathogenic	0.994
BRCA1	P38398-1.2	F386C	Pathogenic	0.99
BRCA1	P38398-1.2	F386D	Pathogenic	0.992
BRCA1	P38398-1.2	F386E	Pathogenic	0.988
BRCA1	P38398-1.2	F386G	Pathogenic	0.997
BRCA1	P38398-1.2	F386H	Pathogenic	0.972
BRCA1	P38398-1.2	F386I	Pathogenic	0.955
BRCA1	P38398-1.2	F386K	Pathogenic	0.979
BRCA1	P38398-1.2	F386L	Pathogenic	0.955
BRCA1	P38398-1.2	F386M	Pathogenic	0.955
BRCA1	P38398-1.2	F386N	Pathogenic	0.991
BRCA1	P38398-1.2	F386P	Pathogenic	0.995
BRCA1	P38398-1.2	F386Q	Pathogenic	0.987
BRCA1	P38398-1.2	F386R	Pathogenic	0.984
BRCA1	P38398-1.2	F386S	Pathogenic	0.993
BRCA1	P38398-1.2	F386T	Pathogenic	0.988
BRCA1	P38398-1.2	F386V	Pathogenic	0.979
BRCA1	P38398-1.2	F386W	Pathogenic	0.956
BRCA1	P38398-1.2	F386Y	Pathogenic	0.864
BRCA1	P38398-1.2	S387A	Pathogenic	0.847
BRCA1	P38398-1.2	S387C	Pathogenic	0.93
BRCA1	P38398-1.2	S387D	Pathogenic	0.912
BRCA1	P38398-1.2	S387E	Pathogenic	0.939
BRCA1	P38398-1.2	S387F	Pathogenic	0.982
BRCA1	P38398-1.2	S387G	Pathogenic	0.925
BRCA1	P38398-1.2	S387H	Pathogenic	0.965
BRCA1	P38398-1.2	S387I	Pathogenic	0.978
BRCA1	P38398-1.2	S387K	Pathogenic	0.965
BRCA1	P38398-1.2	S387L	Pathogenic	0.978
BRCA1	P38398-1.2	S387M	Pathogenic	0.968
BRCA1	P38398-1.2	S387N	Pathogenic	0.89
BRCA1	P38398-1.2	S387P	Pathogenic	0.936
BRCA1	P38398-1.2	S387Q	Pathogenic	0.946
BRCA1	P38398-1.2	S387R	Pathogenic	0.981
BRCA1	P38398-1.2	S387T	Pathogenic	0.884
BRCA1	P38398-1.2	S387V	Pathogenic	0.967
BRCA1	P38398-1.2	S387W	Pathogenic	0.993
BRCA1	P38398-1.2	S387Y	Pathogenic	0.985
BRCA1	P38398-1.2	R388A	Pathogenic	0.991
BRCA1	P38398-1.2	R388C	Pathogenic	0.993
BRCA1	P38398-1.2	R388D	Pathogenic	0.989
BRCA1	P38398-1.2	R388E	Pathogenic	0.968
BRCA1	P38398-1.2	R388F	Pathogenic	0.98
BRCA1	P38398-1.2	R388G	Pathogenic	0.996
BRCA1	P38398-1.2	R388H	Pathogenic	0.96
BRCA1	P38398-1.2	R388I	Pathogenic	0.984
BRCA1	P38398-1.2	R388K	Pathogenic	0.891
BRCA1	P38398-1.2	R388L	Pathogenic	0.977
BRCA1	P38398-1.2	R388M	Pathogenic	0.968
BRCA1	P38398-1.2	R388N	Pathogenic	0.976
BRCA1	P38398-1.2	R388P	Pathogenic	0.989
BRCA1	P38398-1.2	R388Q	Pathogenic	0.949
BRCA1	P38398-1.2	R388S	Pathogenic	0.99
BRCA1	P38398-1.2	R388T	Pathogenic	0.984
BRCA1	P38398-1.2	R388V	Pathogenic	0.99
BRCA1	P38398-1.2	R388W	Pathogenic	0.98
BRCA1	P38398-1.2	R388Y	Pathogenic	0.967
BRCA1	P38398-1.2	S389A	Neutral	0.184
BRCA1	P38398-1.2	S389C	Neutral	0.35
BRCA1	P38398-1.2	S389D	Neutral	0.296
BRCA1	P38398-1.2	S389E	Neutral	0.386
BRCA1	P38398-1.2	S389F	Pathogenic	0.694
BRCA1	P38398-1.2	S389G	Neutral	0.332
BRCA1	P38398-1.2	S389H	Pathogenic	0.527
BRCA1	P38398-1.2	S389I	Pathogenic	0.64
BRCA1	P38398-1.2	S389K	Pathogenic	0.527
BRCA1	P38398-1.2	S389L	Pathogenic	0.64
BRCA1	P38398-1.2	S389M	Pathogenic	0.555
BRCA1	P38398-1.2	S389N	Neutral	0.247
BRCA1	P38398-1.2	S389P	Neutral	0.372
BRCA1	P38398-1.2	S389Q	Neutral	0.415
BRCA1	P38398-1.2	S389R	Pathogenic	0.681
BRCA1	P38398-1.2	S389T	Neutral	0.236
BRCA1	P38398-1.2	S389V	Pathogenic	0.541
BRCA1	P38398-1.2	S389W	Pathogenic	0.858
BRCA1	P38398-1.2	S389Y	Pathogenic	0.725
BRCA1	P38398-1.2	D390A	Pathogenic	0.794
BRCA1	P38398-1.2	D390C	Pathogenic	0.782
BRCA1	P38398-1.2	D390E	Neutral	0.445
BRCA1	P38398-1.2	D390F	Pathogenic	0.894
BRCA1	P38398-1.2	D390G	Pathogenic	0.805
BRCA1	P38398-1.2	D390H	Pathogenic	0.742
BRCA1	P38398-1.2	D390I	Pathogenic	0.868
BRCA1	P38398-1.2	D390K	Pathogenic	0.81
BRCA1	P38398-1.2	D390L	Pathogenic	0.905
BRCA1	P38398-1.2	D390M	Pathogenic	0.87
BRCA1	P38398-1.2	D390N	Neutral	0.464
BRCA1	P38398-1.2	D390P	Pathogenic	0.615
BRCA1	P38398-1.2	D390Q	Pathogenic	0.648
BRCA1	P38398-1.2	D390R	Pathogenic	0.891
BRCA1	P38398-1.2	D390S	Pathogenic	0.622
BRCA1	P38398-1.2	D390T	Pathogenic	0.622
BRCA1	P38398-1.2	D390V	Pathogenic	0.814
BRCA1	P38398-1.2	D390W	Pathogenic	0.957
BRCA1	P38398-1.2	D390Y	Pathogenic	0.907
BRCA1	P38398-1.2	E391A	Neutral	0.377
BRCA1	P38398-1.2	E391C	Pathogenic	0.538
BRCA1	P38398-1.2	E391D	Neutral	0.108
BRCA1	P38398-1.2	E391F	Neutral	0.46
BRCA1	P38398-1.2	E391G	Pathogenic	0.572
BRCA1	P38398-1.2	E391H	Neutral	0.168
BRCA1	P38398-1.2	E391I	Neutral	0.4
BRCA1	P38398-1.2	E391K	Neutral	0.171
BRCA1	P38398-1.2	E391L	Neutral	0.401
BRCA1	P38398-1.2	E391M	Neutral	0.319
BRCA1	P38398-1.2	E391N	Neutral	0.183
BRCA1	P38398-1.2	E391P	Neutral	0.264
BRCA1	P38398-1.2	E391Q	Neutral	0.083
BRCA1	P38398-1.2	E391R	Neutral	0.284
BRCA1	P38398-1.2	E391S	Neutral	0.27
BRCA1	P38398-1.2	E391T	Neutral	0.253
BRCA1	P38398-1.2	E391V	Neutral	0.269
BRCA1	P38398-1.2	E391W	Pathogenic	0.611
BRCA1	P38398-1.2	E391Y	Neutral	0.407
BRCA1	P38398-1.2	L392A	Neutral	0.017
BRCA1	P38398-1.2	L392C	Neutral	0.011
BRCA1	P38398-1.2	L392D	Neutral	0.028
BRCA1	P38398-1.2	L392E	Neutral	0.013
BRCA1	P38398-1.2	L392F	Neutral	0.004
BRCA1	P38398-1.2	L392G	Neutral	0.071
BRCA1	P38398-1.2	L392H	Neutral	0.011
BRCA1	P38398-1.2	L392I	Neutral	0.002
BRCA1	P38398-1.2	L392K	Neutral	0.008
BRCA1	P38398-1.2	L392M	Neutral	0.002
BRCA1	P38398-1.2	L392N	Neutral	0.018
BRCA1	P38398-1.2	L392P	Neutral	0.021
BRCA1	P38398-1.2	L392Q	Neutral	0.008
BRCA1	P38398-1.2	L392R	Neutral	0.011
BRCA1	P38398-1.2	L392S	Neutral	0.021
BRCA1	P38398-1.2	L392T	Neutral	0.009
BRCA1	P38398-1.2	L392V	Neutral	0.004
BRCA1	P38398-1.2	L392W	Neutral	0.016
BRCA1	P38398-1.2	L392Y	Neutral	0.007
BRCA1	P38398-1.2	L393A	Pathogenic	0.711
BRCA1	P38398-1.2	L393C	Pathogenic	0.621
BRCA1	P38398-1.2	L393D	Pathogenic	0.808
BRCA1	P38398-1.2	L393E	Pathogenic	0.663
BRCA1	P38398-1.2	L393F	Neutral	0.387
BRCA1	P38398-1.2	L393G	Pathogenic	0.918
BRCA1	P38398-1.2	L393H	Pathogenic	0.621
BRCA1	P38398-1.2	L393I	Neutral	0.193
BRCA1	P38398-1.2	L393K	Pathogenic	0.554
BRCA1	P38398-1.2	L393M	Neutral	0.192
BRCA1	P38398-1.2	L393N	Pathogenic	0.725
BRCA1	P38398-1.2	L393P	Pathogenic	0.755
BRCA1	P38398-1.2	L393Q	Pathogenic	0.552
BRCA1	P38398-1.2	L393R	Pathogenic	0.624
BRCA1	P38398-1.2	L393S	Pathogenic	0.755
BRCA1	P38398-1.2	L393T	Pathogenic	0.58
BRCA1	P38398-1.2	L393V	Neutral	0.342
BRCA1	P38398-1.2	L393W	Pathogenic	0.707
BRCA1	P38398-1.2	L393Y	Pathogenic	0.506
BRCA1	P38398-1.2	G394A	Neutral	0.035
BRCA1	P38398-1.2	G394C	Neutral	0.14
BRCA1	P38398-1.2	G394D	Neutral	0.081
BRCA1	P38398-1.2	G394E	Neutral	0.16
BRCA1	P38398-1.2	G394F	Neutral	0.323
BRCA1	P38398-1.2	G394H	Neutral	0.19
BRCA1	P38398-1.2	G394I	Neutral	0.35
BRCA1	P38398-1.2	G394K	Neutral	0.252
BRCA1	P38398-1.2	G394L	Neutral	0.35
BRCA1	P38398-1.2	G394M	Neutral	0.274
BRCA1	P38398-1.2	G394N	Neutral	0.065
BRCA1	P38398-1.2	G394P	Neutral	0.111
BRCA1	P38398-1.2	G394Q	Neutral	0.177
BRCA1	P38398-1.2	G394R	Neutral	0.31
BRCA1	P38398-1.2	G394S	Neutral	0.04
BRCA1	P38398-1.2	G394T	Neutral	0.119
BRCA1	P38398-1.2	G394V	Neutral	0.199
BRCA1	P38398-1.2	G394W	Neutral	0.38
BRCA1	P38398-1.2	G394Y	Neutral	0.357
BRCA1	P38398-1.2	S395A	Neutral	0.459
BRCA1	P38398-1.2	S395C	Pathogenic	0.67
BRCA1	P38398-1.2	S395D	Pathogenic	0.613
BRCA1	P38398-1.2	S395E	Pathogenic	0.703
BRCA1	P38398-1.2	S395F	Pathogenic	0.895
BRCA1	P38398-1.2	S395G	Pathogenic	0.652
BRCA1	P38398-1.2	S395H	Pathogenic	0.808
BRCA1	P38398-1.2	S395I	Pathogenic	0.87
BRCA1	P38398-1.2	S395K	Pathogenic	0.807
BRCA1	P38398-1.2	S395L	Pathogenic	0.87
BRCA1	P38398-1.2	S395M	Pathogenic	0.824
BRCA1	P38398-1.2	S395N	Pathogenic	0.552
BRCA1	P38398-1.2	S395P	Pathogenic	0.69
BRCA1	P38398-1.2	S395Q	Pathogenic	0.727
BRCA1	P38398-1.2	S395R	Pathogenic	0.889
BRCA1	P38398-1.2	S395T	Pathogenic	0.537
BRCA1	P38398-1.2	S395V	Pathogenic	0.816
BRCA1	P38398-1.2	S395W	Pathogenic	0.958
BRCA1	P38398-1.2	S395Y	Pathogenic	0.908
BRCA1	P38398-1.2	D396A	Pathogenic	0.721
BRCA1	P38398-1.2	D396C	Pathogenic	0.707
BRCA1	P38398-1.2	D396E	Neutral	0.35
BRCA1	P38398-1.2	D396F	Pathogenic	0.85
BRCA1	P38398-1.2	D396G	Pathogenic	0.734
BRCA1	P38398-1.2	D396H	Pathogenic	0.659
BRCA1	P38398-1.2	D396I	Pathogenic	0.816
BRCA1	P38398-1.2	D396K	Pathogenic	0.74
BRCA1	P38398-1.2	D396L	Pathogenic	0.864
BRCA1	P38398-1.2	D396M	Pathogenic	0.817
BRCA1	P38398-1.2	D396N	Neutral	0.367
BRCA1	P38398-1.2	D396P	Pathogenic	0.517
BRCA1	P38398-1.2	D396Q	Pathogenic	0.553
BRCA1	P38398-1.2	D396R	Pathogenic	0.846
BRCA1	P38398-1.2	D396S	Pathogenic	0.524
BRCA1	P38398-1.2	D396T	Pathogenic	0.525
BRCA1	P38398-1.2	D396V	Pathogenic	0.746
BRCA1	P38398-1.2	D396W	Pathogenic	0.938
BRCA1	P38398-1.2	D396Y	Pathogenic	0.868
BRCA1	P38398-1.2	D397A	Neutral	0.055
BRCA1	P38398-1.2	D397C	Neutral	0.052
BRCA1	P38398-1.2	D397E	Neutral	0.012
BRCA1	P38398-1.2	D397F	Neutral	0.113
BRCA1	P38398-1.2	D397G	Neutral	0.059
BRCA1	P38398-1.2	D397H	Neutral	0.042
BRCA1	P38398-1.2	D397I	Neutral	0.091
BRCA1	P38398-1.2	D397K	Neutral	0.061
BRCA1	P38398-1.2	D397L	Neutral	0.126
BRCA1	P38398-1.2	D397M	Neutral	0.092
BRCA1	P38398-1.2	D397N	Neutral	0.013
BRCA1	P38398-1.2	D397P	Neutral	0.024
BRCA1	P38398-1.2	D397Q	Neutral	0.027
BRCA1	P38398-1.2	D397R	Neutral	0.11
BRCA1	P38398-1.2	D397S	Neutral	0.024
BRCA1	P38398-1.2	D397T	Neutral	0.024
BRCA1	P38398-1.2	D397V	Neutral	0.062
BRCA1	P38398-1.2	D397W	Neutral	0.253
BRCA1	P38398-1.2	D397Y	Neutral	0.129
BRCA1	P38398-1.2	S398A	Neutral	0.082
BRCA1	P38398-1.2	S398C	Neutral	0.175
BRCA1	P38398-1.2	S398D	Neutral	0.142
BRCA1	P38398-1.2	S398E	Neutral	0.199
BRCA1	P38398-1.2	S398F	Neutral	0.472
BRCA1	P38398-1.2	S398G	Neutral	0.164
BRCA1	P38398-1.2	S398H	Neutral	0.306
BRCA1	P38398-1.2	S398I	Neutral	0.412
BRCA1	P38398-1.2	S398K	Neutral	0.305
BRCA1	P38398-1.2	S398L	Neutral	0.412
BRCA1	P38398-1.2	S398M	Neutral	0.33
BRCA1	P38398-1.2	S398N	Neutral	0.115
BRCA1	P38398-1.2	S398P	Neutral	0.189
BRCA1	P38398-1.2	S398Q	Neutral	0.219
BRCA1	P38398-1.2	S398R	Neutral	0.458
BRCA1	P38398-1.2	S398T	Neutral	0.108
BRCA1	P38398-1.2	S398V	Neutral	0.317
BRCA1	P38398-1.2	S398W	Pathogenic	0.704
BRCA1	P38398-1.2	S398Y	Pathogenic	0.51
BRCA1	P38398-1.2	H399A	Neutral	0.032
BRCA1	P38398-1.2	H399C	Neutral	0.03
BRCA1	P38398-1.2	H399D	Neutral	0.013
BRCA1	P38398-1.2	H399E	Neutral	0.006
BRCA1	P38398-1.2	H399F	Neutral	0.01
BRCA1	P38398-1.2	H399G	Neutral	0.048
BRCA1	P38398-1.2	H399I	Neutral	0.017
BRCA1	P38398-1.2	H399K	Neutral	0.01
BRCA1	P38398-1.2	H399L	Neutral	0.017
BRCA1	P38398-1.2	H399M	Neutral	0.012
BRCA1	P38398-1.2	H399N	Neutral	0.006
BRCA1	P38398-1.2	H399P	Neutral	0.019
BRCA1	P38398-1.2	H399Q	Neutral	0.006
BRCA1	P38398-1.2	H399R	Neutral	0.01
BRCA1	P38398-1.2	H399S	Neutral	0.02
BRCA1	P38398-1.2	H399T	Neutral	0.018
BRCA1	P38398-1.2	H399V	Neutral	0.02
BRCA1	P38398-1.2	H399W	Neutral	0.027
BRCA1	P38398-1.2	H399Y	Neutral	0.004
BRCA1	P38398-1.2	D400A	Neutral	0.429
BRCA1	P38398-1.2	D400C	Neutral	0.412
BRCA1	P38398-1.2	D400E	Neutral	0.135
BRCA1	P38398-1.2	D400F	Pathogenic	0.621
BRCA1	P38398-1.2	D400G	Neutral	0.445
BRCA1	P38398-1.2	D400H	Neutral	0.359
BRCA1	P38398-1.2	D400I	Pathogenic	0.562
BRCA1	P38398-1.2	D400K	Neutral	0.453
BRCA1	P38398-1.2	D400L	Pathogenic	0.649
BRCA1	P38398-1.2	D400M	Pathogenic	0.565
BRCA1	P38398-1.2	D400N	Neutral	0.144
BRCA1	P38398-1.2	D400P	Neutral	0.237
BRCA1	P38398-1.2	D400Q	Neutral	0.264
BRCA1	P38398-1.2	D400R	Pathogenic	0.614
BRCA1	P38398-1.2	D400S	Neutral	0.242
BRCA1	P38398-1.2	D400T	Neutral	0.243
BRCA1	P38398-1.2	D400V	Neutral	0.46
BRCA1	P38398-1.2	D400W	Pathogenic	0.813
BRCA1	P38398-1.2	D400Y	Pathogenic	0.656
BRCA1	P38398-1.2	G401A	Neutral	0.056
BRCA1	P38398-1.2	G401C	Neutral	0.212
BRCA1	P38398-1.2	G401D	Neutral	0.127
BRCA1	P38398-1.2	G401E	Neutral	0.238
BRCA1	P38398-1.2	G401F	Neutral	0.44
BRCA1	P38398-1.2	G401H	Neutral	0.278
BRCA1	P38398-1.2	G401I	Neutral	0.469
BRCA1	P38398-1.2	G401K	Neutral	0.356
BRCA1	P38398-1.2	G401L	Neutral	0.47
BRCA1	P38398-1.2	G401M	Neutral	0.383
BRCA1	P38398-1.2	G401N	Neutral	0.102
BRCA1	P38398-1.2	G401P	Neutral	0.17
BRCA1	P38398-1.2	G401Q	Neutral	0.261
BRCA1	P38398-1.2	G401R	Neutral	0.425
BRCA1	P38398-1.2	G401S	Neutral	0.064
BRCA1	P38398-1.2	G401T	Neutral	0.181
BRCA1	P38398-1.2	G401V	Neutral	0.29
BRCA1	P38398-1.2	G401W	Pathogenic	0.502
BRCA1	P38398-1.2	G401Y	Neutral	0.477
BRCA1	P38398-1.2	E402A	Neutral	0.001
BRCA1	P38398-1.2	E402C	Neutral	0.003
BRCA1	P38398-1.2	E402D	Neutral	0.0
BRCA1	P38398-1.2	E402F	Neutral	0.002
BRCA1	P38398-1.2	E402G	Neutral	0.003
BRCA1	P38398-1.2	E402H	Neutral	0.0
BRCA1	P38398-1.2	E402I	Neutral	0.001
BRCA1	P38398-1.2	E402K	Neutral	0.0
BRCA1	P38398-1.2	E402L	Neutral	0.001
BRCA1	P38398-1.2	E402M	Neutral	0.001
BRCA1	P38398-1.2	E402N	Neutral	0.0
BRCA1	P38398-1.2	E402P	Neutral	0.001
BRCA1	P38398-1.2	E402Q	Neutral	0.0
BRCA1	P38398-1.2	E402R	Neutral	0.001
BRCA1	P38398-1.2	E402S	Neutral	0.001
BRCA1	P38398-1.2	E402T	Neutral	0.001
BRCA1	P38398-1.2	E402V	Neutral	0.001
BRCA1	P38398-1.2	E402W	Neutral	0.003
BRCA1	P38398-1.2	E402Y	Neutral	0.002
BRCA1	P38398-1.2	S403A	Neutral	0.013
BRCA1	P38398-1.2	S403C	Neutral	0.031
BRCA1	P38398-1.2	S403D	Neutral	0.025
BRCA1	P38398-1.2	S403E	Neutral	0.037
BRCA1	P38398-1.2	S403F	Neutral	0.12
BRCA1	P38398-1.2	S403G	Neutral	0.029
BRCA1	P38398-1.2	S403H	Neutral	0.063
BRCA1	P38398-1.2	S403I	Neutral	0.097
BRCA1	P38398-1.2	S403K	Neutral	0.063
BRCA1	P38398-1.2	S403L	Neutral	0.097
BRCA1	P38398-1.2	S403M	Neutral	0.07
BRCA1	P38398-1.2	S403N	Neutral	0.019
BRCA1	P38398-1.2	S403P	Neutral	0.034
BRCA1	P38398-1.2	S403Q	Neutral	0.041
BRCA1	P38398-1.2	S403R	Neutral	0.114
BRCA1	P38398-1.2	S403T	Neutral	0.018
BRCA1	P38398-1.2	S403V	Neutral	0.066
BRCA1	P38398-1.2	S403W	Neutral	0.267
BRCA1	P38398-1.2	S403Y	Neutral	0.137
BRCA1	P38398-1.2	E404A	Pathogenic	0.836
BRCA1	P38398-1.2	E404C	Pathogenic	0.908
BRCA1	P38398-1.2	E404D	Pathogenic	0.505
BRCA1	P38398-1.2	E404F	Pathogenic	0.878
BRCA1	P38398-1.2	E404G	Pathogenic	0.919
BRCA1	P38398-1.2	E404H	Pathogenic	0.631
BRCA1	P38398-1.2	E404I	Pathogenic	0.849
BRCA1	P38398-1.2	E404K	Pathogenic	0.636
BRCA1	P38398-1.2	E404L	Pathogenic	0.85
BRCA1	P38398-1.2	E404M	Pathogenic	0.799
BRCA1	P38398-1.2	E404N	Pathogenic	0.655
BRCA1	P38398-1.2	E404P	Pathogenic	0.752
BRCA1	P38398-1.2	E404Q	Neutral	0.432
BRCA1	P38398-1.2	E404R	Pathogenic	0.77
BRCA1	P38398-1.2	E404S	Pathogenic	0.758
BRCA1	P38398-1.2	E404T	Pathogenic	0.742
BRCA1	P38398-1.2	E404V	Pathogenic	0.756
BRCA1	P38398-1.2	E404W	Pathogenic	0.93
BRCA1	P38398-1.2	E404Y	Pathogenic	0.853
BRCA1	P38398-1.2	S405A	Neutral	0.059
BRCA1	P38398-1.2	S405C	Neutral	0.131
BRCA1	P38398-1.2	S405D	Neutral	0.106
BRCA1	P38398-1.2	S405E	Neutral	0.15
BRCA1	P38398-1.2	S405F	Neutral	0.389
BRCA1	P38398-1.2	S405G	Neutral	0.123
BRCA1	P38398-1.2	S405H	Neutral	0.238
BRCA1	P38398-1.2	S405I	Neutral	0.332
BRCA1	P38398-1.2	S405K	Neutral	0.238
BRCA1	P38398-1.2	S405L	Neutral	0.333
BRCA1	P38398-1.2	S405M	Neutral	0.259
BRCA1	P38398-1.2	S405N	Neutral	0.084
BRCA1	P38398-1.2	S405P	Neutral	0.142
BRCA1	P38398-1.2	S405Q	Neutral	0.166
BRCA1	P38398-1.2	S405R	Neutral	0.375
BRCA1	P38398-1.2	S405T	Neutral	0.08
BRCA1	P38398-1.2	S405V	Neutral	0.248
BRCA1	P38398-1.2	S405W	Pathogenic	0.628
BRCA1	P38398-1.2	S405Y	Neutral	0.425
BRCA1	P38398-1.2	N406A	Neutral	0.344
BRCA1	P38398-1.2	N406C	Neutral	0.328
BRCA1	P38398-1.2	N406D	Neutral	0.095
BRCA1	P38398-1.2	N406E	Neutral	0.153
BRCA1	P38398-1.2	N406F	Neutral	0.478
BRCA1	P38398-1.2	N406G	Neutral	0.28
BRCA1	P38398-1.2	N406H	Neutral	0.131
BRCA1	P38398-1.2	N406I	Neutral	0.418
BRCA1	P38398-1.2	N406K	Neutral	0.242
BRCA1	P38398-1.2	N406L	Neutral	0.418
BRCA1	P38398-1.2	N406M	Neutral	0.335
BRCA1	P38398-1.2	N406P	Neutral	0.238
BRCA1	P38398-1.2	N406Q	Neutral	0.167
BRCA1	P38398-1.2	N406R	Neutral	0.299
BRCA1	P38398-1.2	N406S	Neutral	0.134
BRCA1	P38398-1.2	N406T	Neutral	0.125
BRCA1	P38398-1.2	N406V	Neutral	0.322
BRCA1	P38398-1.2	N406W	Pathogenic	0.709
BRCA1	P38398-1.2	N406Y	Neutral	0.425
BRCA1	P38398-1.2	A407C	Neutral	0.021
BRCA1	P38398-1.2	A407D	Neutral	0.047
BRCA1	P38398-1.2	A407E	Neutral	0.049
BRCA1	P38398-1.2	A407F	Neutral	0.116
BRCA1	P38398-1.2	A407G	Neutral	0.021
BRCA1	P38398-1.2	A407H	Neutral	0.084
BRCA1	P38398-1.2	A407I	Neutral	0.066
BRCA1	P38398-1.2	A407K	Neutral	0.084
BRCA1	P38398-1.2	A407L	Neutral	0.067
BRCA1	P38398-1.2	A407M	Neutral	0.067
BRCA1	P38398-1.2	A407N	Neutral	0.053
BRCA1	P38398-1.2	A407P	Neutral	0.033
BRCA1	P38398-1.2	A407Q	Neutral	0.055
BRCA1	P38398-1.2	A407R	Neutral	0.108
BRCA1	P38398-1.2	A407S	Neutral	0.011
BRCA1	P38398-1.2	A407T	Neutral	0.025
BRCA1	P38398-1.2	A407V	Neutral	0.032
BRCA1	P38398-1.2	A407W	Neutral	0.258
BRCA1	P38398-1.2	A407Y	Neutral	0.132
BRCA1	P38398-1.2	K408A	Neutral	0.32
BRCA1	P38398-1.2	K408C	Neutral	0.387
BRCA1	P38398-1.2	K408D	Neutral	0.22
BRCA1	P38398-1.2	K408E	Neutral	0.083
BRCA1	P38398-1.2	K408F	Neutral	0.173
BRCA1	P38398-1.2	K408G	Pathogenic	0.51
BRCA1	P38398-1.2	K408H	Neutral	0.132
BRCA1	P38398-1.2	K408I	Neutral	0.211
BRCA1	P38398-1.2	K408L	Neutral	0.157
BRCA1	P38398-1.2	K408M	Neutral	0.115
BRCA1	P38398-1.2	K408N	Neutral	0.149
BRCA1	P38398-1.2	K408P	Neutral	0.219
BRCA1	P38398-1.2	K408Q	Neutral	0.075
BRCA1	P38398-1.2	K408R	Neutral	0.046
BRCA1	P38398-1.2	K408S	Neutral	0.224
BRCA1	P38398-1.2	K408T	Neutral	0.209
BRCA1	P38398-1.2	K408V	Neutral	0.223
BRCA1	P38398-1.2	K408W	Neutral	0.279
BRCA1	P38398-1.2	K408Y	Neutral	0.144
BRCA1	P38398-1.2	V409A	Neutral	0.054
BRCA1	P38398-1.2	V409C	Neutral	0.052
BRCA1	P38398-1.2	V409D	Neutral	0.09
BRCA1	P38398-1.2	V409E	Neutral	0.052
BRCA1	P38398-1.2	V409F	Neutral	0.065
BRCA1	P38398-1.2	V409G	Neutral	0.206
BRCA1	P38398-1.2	V409H	Neutral	0.089
BRCA1	P38398-1.2	V409I	Neutral	0.013
BRCA1	P38398-1.2	V409K	Neutral	0.088
BRCA1	P38398-1.2	V409L	Neutral	0.026
BRCA1	P38398-1.2	V409M	Neutral	0.026
BRCA1	P38398-1.2	V409N	Neutral	0.081
BRCA1	P38398-1.2	V409P	Neutral	0.067
BRCA1	P38398-1.2	V409Q	Neutral	0.058
BRCA1	P38398-1.2	V409R	Neutral	0.157
BRCA1	P38398-1.2	V409S	Neutral	0.094
BRCA1	P38398-1.2	V409T	Neutral	0.031
BRCA1	P38398-1.2	V409W	Neutral	0.21
BRCA1	P38398-1.2	V409Y	Neutral	0.074
BRCA1	P38398-1.2	A410C	Pathogenic	0.544
BRCA1	P38398-1.2	A410D	Pathogenic	0.733
BRCA1	P38398-1.2	A410E	Pathogenic	0.74
BRCA1	P38398-1.2	A410F	Pathogenic	0.878
BRCA1	P38398-1.2	A410G	Pathogenic	0.546
BRCA1	P38398-1.2	A410H	Pathogenic	0.836
BRCA1	P38398-1.2	A410I	Pathogenic	0.797
BRCA1	P38398-1.2	A410K	Pathogenic	0.834
BRCA1	P38398-1.2	A410L	Pathogenic	0.798
BRCA1	P38398-1.2	A410M	Pathogenic	0.799
BRCA1	P38398-1.2	A410N	Pathogenic	0.755
BRCA1	P38398-1.2	A410P	Pathogenic	0.654
BRCA1	P38398-1.2	A410Q	Pathogenic	0.762
BRCA1	P38398-1.2	A410R	Pathogenic	0.871
BRCA1	P38398-1.2	A410S	Neutral	0.385
BRCA1	P38398-1.2	A410T	Pathogenic	0.585
BRCA1	P38398-1.2	A410V	Pathogenic	0.644
BRCA1	P38398-1.2	A410W	Pathogenic	0.951
BRCA1	P38398-1.2	A410Y	Pathogenic	0.894
BRCA1	P38398-1.2	D411A	Neutral	0.019
BRCA1	P38398-1.2	D411C	Neutral	0.018
BRCA1	P38398-1.2	D411E	Neutral	0.004
BRCA1	P38398-1.2	D411F	Neutral	0.041
BRCA1	P38398-1.2	D411G	Neutral	0.02
BRCA1	P38398-1.2	D411H	Neutral	0.014
BRCA1	P38398-1.2	D411I	Neutral	0.032
BRCA1	P38398-1.2	D411K	Neutral	0.021
BRCA1	P38398-1.2	D411L	Neutral	0.046
BRCA1	P38398-1.2	D411M	Neutral	0.033
BRCA1	P38398-1.2	D411N	Neutral	0.004
BRCA1	P38398-1.2	D411P	Neutral	0.008
BRCA1	P38398-1.2	D411Q	Neutral	0.009
BRCA1	P38398-1.2	D411R	Neutral	0.04
BRCA1	P38398-1.2	D411S	Neutral	0.008
BRCA1	P38398-1.2	D411T	Neutral	0.008
BRCA1	P38398-1.2	D411V	Neutral	0.022
BRCA1	P38398-1.2	D411W	Neutral	0.102
BRCA1	P38398-1.2	D411Y	Neutral	0.047
BRCA1	P38398-1.2	V412A	Neutral	0.152
BRCA1	P38398-1.2	V412C	Neutral	0.147
BRCA1	P38398-1.2	V412D	Neutral	0.236
BRCA1	P38398-1.2	V412E	Neutral	0.147
BRCA1	P38398-1.2	V412F	Neutral	0.179
BRCA1	P38398-1.2	V412G	Neutral	0.448
BRCA1	P38398-1.2	V412H	Neutral	0.235
BRCA1	P38398-1.2	V412I	Neutral	0.038
BRCA1	P38398-1.2	V412K	Neutral	0.233
BRCA1	P38398-1.2	V412L	Neutral	0.076
BRCA1	P38398-1.2	V412M	Neutral	0.077
BRCA1	P38398-1.2	V412N	Neutral	0.217
BRCA1	P38398-1.2	V412P	Neutral	0.184
BRCA1	P38398-1.2	V412Q	Neutral	0.162
BRCA1	P38398-1.2	V412R	Neutral	0.369
BRCA1	P38398-1.2	V412S	Neutral	0.245
BRCA1	P38398-1.2	V412T	Neutral	0.092
BRCA1	P38398-1.2	V412W	Neutral	0.455
BRCA1	P38398-1.2	V412Y	Neutral	0.2
BRCA1	P38398-1.2	L413A	Neutral	0.099
BRCA1	P38398-1.2	L413C	Neutral	0.068
BRCA1	P38398-1.2	L413D	Neutral	0.158
BRCA1	P38398-1.2	L413E	Neutral	0.08
BRCA1	P38398-1.2	L413F	Neutral	0.027
BRCA1	P38398-1.2	L413G	Neutral	0.331
BRCA1	P38398-1.2	L413H	Neutral	0.068
BRCA1	P38398-1.2	L413I	Neutral	0.01
BRCA1	P38398-1.2	L413K	Neutral	0.052
BRCA1	P38398-1.2	L413M	Neutral	0.01
BRCA1	P38398-1.2	L413N	Neutral	0.105
BRCA1	P38398-1.2	L413P	Neutral	0.12
BRCA1	P38398-1.2	L413Q	Neutral	0.052
BRCA1	P38398-1.2	L413R	Neutral	0.069
BRCA1	P38398-1.2	L413S	Neutral	0.12
BRCA1	P38398-1.2	L413T	Neutral	0.058
BRCA1	P38398-1.2	L413V	Neutral	0.023
BRCA1	P38398-1.2	L413W	Neutral	0.097
BRCA1	P38398-1.2	L413Y	Neutral	0.044
BRCA1	P38398-1.2	D414A	Neutral	0.168
BRCA1	P38398-1.2	D414C	Neutral	0.159
BRCA1	P38398-1.2	D414E	Neutral	0.04
BRCA1	P38398-1.2	D414F	Neutral	0.306
BRCA1	P38398-1.2	D414G	Neutral	0.177
BRCA1	P38398-1.2	D414H	Neutral	0.131
BRCA1	P38398-1.2	D414I	Neutral	0.257
BRCA1	P38398-1.2	D414K	Neutral	0.182
BRCA1	P38398-1.2	D414L	Neutral	0.332
BRCA1	P38398-1.2	D414M	Neutral	0.259
BRCA1	P38398-1.2	D414N	Neutral	0.043
BRCA1	P38398-1.2	D414P	Neutral	0.077
BRCA1	P38398-1.2	D414Q	Neutral	0.088
BRCA1	P38398-1.2	D414R	Neutral	0.3
BRCA1	P38398-1.2	D414S	Neutral	0.079
BRCA1	P38398-1.2	D414T	Neutral	0.079
BRCA1	P38398-1.2	D414V	Neutral	0.186
BRCA1	P38398-1.2	D414W	Pathogenic	0.54
BRCA1	P38398-1.2	D414Y	Neutral	0.339
BRCA1	P38398-1.2	V415A	Neutral	0.103
BRCA1	P38398-1.2	V415C	Neutral	0.099
BRCA1	P38398-1.2	V415D	Neutral	0.164
BRCA1	P38398-1.2	V415E	Neutral	0.099
BRCA1	P38398-1.2	V415F	Neutral	0.122
BRCA1	P38398-1.2	V415G	Neutral	0.342
BRCA1	P38398-1.2	V415H	Neutral	0.164
BRCA1	P38398-1.2	V415I	Neutral	0.025
BRCA1	P38398-1.2	V415K	Neutral	0.163
BRCA1	P38398-1.2	V415L	Neutral	0.05
BRCA1	P38398-1.2	V415M	Neutral	0.051
BRCA1	P38398-1.2	V415N	Neutral	0.15
BRCA1	P38398-1.2	V415P	Neutral	0.126
BRCA1	P38398-1.2	V415Q	Neutral	0.11
BRCA1	P38398-1.2	V415R	Neutral	0.272
BRCA1	P38398-1.2	V415S	Neutral	0.171
BRCA1	P38398-1.2	V415T	Neutral	0.06
BRCA1	P38398-1.2	V415W	Neutral	0.347
BRCA1	P38398-1.2	V415Y	Neutral	0.138
BRCA1	P38398-1.2	L416A	Neutral	0.213
BRCA1	P38398-1.2	L416C	Neutral	0.152
BRCA1	P38398-1.2	L416D	Neutral	0.317
BRCA1	P38398-1.2	L416E	Neutral	0.178
BRCA1	P38398-1.2	L416F	Neutral	0.065
BRCA1	P38398-1.2	L416G	Pathogenic	0.55
BRCA1	P38398-1.2	L416H	Neutral	0.153
BRCA1	P38398-1.2	L416I	Neutral	0.026
BRCA1	P38398-1.2	L416K	Neutral	0.12
BRCA1	P38398-1.2	L416M	Neutral	0.025
BRCA1	P38398-1.2	L416N	Neutral	0.224
BRCA1	P38398-1.2	L416P	Neutral	0.253
BRCA1	P38398-1.2	L416Q	Neutral	0.12
BRCA1	P38398-1.2	L416R	Neutral	0.154
BRCA1	P38398-1.2	L416S	Neutral	0.253
BRCA1	P38398-1.2	L416T	Neutral	0.132
BRCA1	P38398-1.2	L416V	Neutral	0.054
BRCA1	P38398-1.2	L416W	Neutral	0.21
BRCA1	P38398-1.2	L416Y	Neutral	0.101
BRCA1	P38398-1.2	N417A	Neutral	0.077
BRCA1	P38398-1.2	N417C	Neutral	0.072
BRCA1	P38398-1.2	N417D	Neutral	0.016
BRCA1	P38398-1.2	N417E	Neutral	0.028
BRCA1	P38398-1.2	N417F	Neutral	0.127
BRCA1	P38398-1.2	N417G	Neutral	0.058
BRCA1	P38398-1.2	N417H	Neutral	0.023
BRCA1	P38398-1.2	N417I	Neutral	0.102
BRCA1	P38398-1.2	N417K	Neutral	0.048
BRCA1	P38398-1.2	N417L	Neutral	0.102
BRCA1	P38398-1.2	N417M	Neutral	0.074
BRCA1	P38398-1.2	N417P	Neutral	0.047
BRCA1	P38398-1.2	N417Q	Neutral	0.031
BRCA1	P38398-1.2	N417R	Neutral	0.063
BRCA1	P38398-1.2	N417S	Neutral	0.024
BRCA1	P38398-1.2	N417T	Neutral	0.022
BRCA1	P38398-1.2	N417V	Neutral	0.07
BRCA1	P38398-1.2	N417W	Neutral	0.278
BRCA1	P38398-1.2	N417Y	Neutral	0.105
BRCA1	P38398-1.2	E418A	Neutral	0.098
BRCA1	P38398-1.2	E418C	Neutral	0.173
BRCA1	P38398-1.2	E418D	Neutral	0.021
BRCA1	P38398-1.2	E418F	Neutral	0.133
BRCA1	P38398-1.2	E418G	Neutral	0.193
BRCA1	P38398-1.2	E418H	Neutral	0.035
BRCA1	P38398-1.2	E418I	Neutral	0.107
BRCA1	P38398-1.2	E418K	Neutral	0.036
BRCA1	P38398-1.2	E418L	Neutral	0.107
BRCA1	P38398-1.2	E418M	Neutral	0.078
BRCA1	P38398-1.2	E418N	Neutral	0.039
BRCA1	P38398-1.2	E418P	Neutral	0.061
BRCA1	P38398-1.2	E418Q	Neutral	0.016
BRCA1	P38398-1.2	E418R	Neutral	0.067
BRCA1	P38398-1.2	E418S	Neutral	0.062
BRCA1	P38398-1.2	E418T	Neutral	0.057
BRCA1	P38398-1.2	E418V	Neutral	0.062
BRCA1	P38398-1.2	E418W	Neutral	0.22
BRCA1	P38398-1.2	E418Y	Neutral	0.11
BRCA1	P38398-1.2	V419A	Neutral	0.051
BRCA1	P38398-1.2	V419C	Neutral	0.049
BRCA1	P38398-1.2	V419D	Neutral	0.085
BRCA1	P38398-1.2	V419E	Neutral	0.049
BRCA1	P38398-1.2	V419F	Neutral	0.062
BRCA1	P38398-1.2	V419G	Neutral	0.197
BRCA1	P38398-1.2	V419H	Neutral	0.085
BRCA1	P38398-1.2	V419I	Neutral	0.012
BRCA1	P38398-1.2	V419K	Neutral	0.084
BRCA1	P38398-1.2	V419L	Neutral	0.024
BRCA1	P38398-1.2	V419M	Neutral	0.025
BRCA1	P38398-1.2	V419N	Neutral	0.077
BRCA1	P38398-1.2	V419P	Neutral	0.064
BRCA1	P38398-1.2	V419Q	Neutral	0.055
BRCA1	P38398-1.2	V419R	Neutral	0.15
BRCA1	P38398-1.2	V419S	Neutral	0.089
BRCA1	P38398-1.2	V419T	Neutral	0.03
BRCA1	P38398-1.2	V419W	Neutral	0.201
BRCA1	P38398-1.2	V419Y	Neutral	0.07
BRCA1	P38398-1.2	D420A	Neutral	0.404
BRCA1	P38398-1.2	D420C	Neutral	0.387
BRCA1	P38398-1.2	D420E	Neutral	0.123
BRCA1	P38398-1.2	D420F	Pathogenic	0.596
BRCA1	P38398-1.2	D420G	Neutral	0.419
BRCA1	P38398-1.2	D420H	Neutral	0.335
BRCA1	P38398-1.2	D420I	Pathogenic	0.536
BRCA1	P38398-1.2	D420K	Neutral	0.427
BRCA1	P38398-1.2	D420L	Pathogenic	0.625
BRCA1	P38398-1.2	D420M	Pathogenic	0.539
BRCA1	P38398-1.2	D420N	Neutral	0.132
BRCA1	P38398-1.2	D420P	Neutral	0.219
BRCA1	P38398-1.2	D420Q	Neutral	0.244
BRCA1	P38398-1.2	D420R	Pathogenic	0.589
BRCA1	P38398-1.2	D420S	Neutral	0.224
BRCA1	P38398-1.2	D420T	Neutral	0.224
BRCA1	P38398-1.2	D420V	Neutral	0.434
BRCA1	P38398-1.2	D420W	Pathogenic	0.797
BRCA1	P38398-1.2	D420Y	Pathogenic	0.632
BRCA1	P38398-1.2	E421A	Neutral	0.121
BRCA1	P38398-1.2	E421C	Neutral	0.209
BRCA1	P38398-1.2	E421D	Neutral	0.027
BRCA1	P38398-1.2	E421F	Neutral	0.162
BRCA1	P38398-1.2	E421G	Neutral	0.233
BRCA1	P38398-1.2	E421H	Neutral	0.044
BRCA1	P38398-1.2	E421I	Neutral	0.132
BRCA1	P38398-1.2	E421K	Neutral	0.045
BRCA1	P38398-1.2	E421L	Neutral	0.132
BRCA1	P38398-1.2	E421M	Neutral	0.096
BRCA1	P38398-1.2	E421N	Neutral	0.049
BRCA1	P38398-1.2	E421P	Neutral	0.076
BRCA1	P38398-1.2	E421Q	Neutral	0.02
BRCA1	P38398-1.2	E421R	Neutral	0.083
BRCA1	P38398-1.2	E421S	Neutral	0.078
BRCA1	P38398-1.2	E421T	Neutral	0.072
BRCA1	P38398-1.2	E421V	Neutral	0.077
BRCA1	P38398-1.2	E421W	Neutral	0.263
BRCA1	P38398-1.2	E421Y	Neutral	0.135
BRCA1	P38398-1.2	Y422A	Neutral	0.26
BRCA1	P38398-1.2	Y422C	Neutral	0.189
BRCA1	P38398-1.2	Y422D	Neutral	0.225
BRCA1	P38398-1.2	Y422E	Neutral	0.119
BRCA1	P38398-1.2	Y422F	Neutral	0.012
BRCA1	P38398-1.2	Y422G	Neutral	0.433
BRCA1	P38398-1.2	Y422H	Neutral	0.026
BRCA1	P38398-1.2	Y422I	Neutral	0.064
BRCA1	P38398-1.2	Y422K	Neutral	0.07
BRCA1	P38398-1.2	Y422L	Neutral	0.064
BRCA1	P38398-1.2	Y422M	Neutral	0.065
BRCA1	P38398-1.2	Y422N	Neutral	0.153
BRCA1	P38398-1.2	Y422P	Neutral	0.234
BRCA1	P38398-1.2	Y422Q	Neutral	0.078
BRCA1	P38398-1.2	Y422R	Neutral	0.072
BRCA1	P38398-1.2	Y422S	Neutral	0.234
BRCA1	P38398-1.2	Y422T	Neutral	0.164
BRCA1	P38398-1.2	Y422V	Neutral	0.095
BRCA1	P38398-1.2	Y422W	Neutral	0.025
BRCA1	P38398-1.2	S423A	Neutral	0.201
BRCA1	P38398-1.2	S423C	Neutral	0.376
BRCA1	P38398-1.2	S423D	Neutral	0.32
BRCA1	P38398-1.2	S423E	Neutral	0.413
BRCA1	P38398-1.2	S423F	Pathogenic	0.717
BRCA1	P38398-1.2	S423G	Neutral	0.358
BRCA1	P38398-1.2	S423H	Pathogenic	0.555
BRCA1	P38398-1.2	S423I	Pathogenic	0.665
BRCA1	P38398-1.2	S423K	Pathogenic	0.554
BRCA1	P38398-1.2	S423L	Pathogenic	0.665
BRCA1	P38398-1.2	S423M	Pathogenic	0.582
BRCA1	P38398-1.2	S423N	Neutral	0.268
BRCA1	P38398-1.2	S423P	Neutral	0.398
BRCA1	P38398-1.2	S423Q	Neutral	0.442
BRCA1	P38398-1.2	S423R	Pathogenic	0.705
BRCA1	P38398-1.2	S423T	Neutral	0.256
BRCA1	P38398-1.2	S423V	Pathogenic	0.568
BRCA1	P38398-1.2	S423W	Pathogenic	0.871
BRCA1	P38398-1.2	S423Y	Pathogenic	0.746
BRCA1	P38398-1.2	G424A	Neutral	0.262
BRCA1	P38398-1.2	G424C	Pathogenic	0.614
BRCA1	P38398-1.2	G424D	Neutral	0.463
BRCA1	P38398-1.2	G424E	Pathogenic	0.65
BRCA1	P38398-1.2	G424F	Pathogenic	0.823
BRCA1	P38398-1.2	G424H	Pathogenic	0.696
BRCA1	P38398-1.2	G424I	Pathogenic	0.84
BRCA1	P38398-1.2	G424K	Pathogenic	0.767
BRCA1	P38398-1.2	G424L	Pathogenic	0.84
BRCA1	P38398-1.2	G424M	Pathogenic	0.787
BRCA1	P38398-1.2	G424N	Neutral	0.402
BRCA1	P38398-1.2	G424P	Pathogenic	0.549
BRCA1	P38398-1.2	G424Q	Pathogenic	0.677
BRCA1	P38398-1.2	G424R	Pathogenic	0.814
BRCA1	P38398-1.2	G424S	Neutral	0.29
BRCA1	P38398-1.2	G424T	Pathogenic	0.567
BRCA1	P38398-1.2	G424V	Pathogenic	0.707
BRCA1	P38398-1.2	G424W	Pathogenic	0.857
BRCA1	P38398-1.2	G424Y	Pathogenic	0.844
BRCA1	P38398-1.2	S425A	Pathogenic	0.517
BRCA1	P38398-1.2	S425C	Pathogenic	0.719
BRCA1	P38398-1.2	S425D	Pathogenic	0.666
BRCA1	P38398-1.2	S425E	Pathogenic	0.749
BRCA1	P38398-1.2	S425F	Pathogenic	0.915
BRCA1	P38398-1.2	S425G	Pathogenic	0.703
BRCA1	P38398-1.2	S425H	Pathogenic	0.841
BRCA1	P38398-1.2	S425I	Pathogenic	0.894
BRCA1	P38398-1.2	S425K	Pathogenic	0.841
BRCA1	P38398-1.2	S425L	Pathogenic	0.894
BRCA1	P38398-1.2	S425M	Pathogenic	0.856
BRCA1	P38398-1.2	S425N	Pathogenic	0.609
BRCA1	P38398-1.2	S425P	Pathogenic	0.738
BRCA1	P38398-1.2	S425Q	Pathogenic	0.771
BRCA1	P38398-1.2	S425R	Pathogenic	0.91
BRCA1	P38398-1.2	S425T	Pathogenic	0.594
BRCA1	P38398-1.2	S425V	Pathogenic	0.848
BRCA1	P38398-1.2	S425W	Pathogenic	0.966
BRCA1	P38398-1.2	S425Y	Pathogenic	0.926
BRCA1	P38398-1.2	S426A	Neutral	0.196
BRCA1	P38398-1.2	S426C	Neutral	0.367
BRCA1	P38398-1.2	S426D	Neutral	0.312
BRCA1	P38398-1.2	S426E	Neutral	0.404
BRCA1	P38398-1.2	S426F	Pathogenic	0.71
BRCA1	P38398-1.2	S426G	Neutral	0.349
BRCA1	P38398-1.2	S426H	Pathogenic	0.546
BRCA1	P38398-1.2	S426I	Pathogenic	0.657
BRCA1	P38398-1.2	S426K	Pathogenic	0.546
BRCA1	P38398-1.2	S426L	Pathogenic	0.657
BRCA1	P38398-1.2	S426M	Pathogenic	0.574
BRCA1	P38398-1.2	S426N	Neutral	0.261
BRCA1	P38398-1.2	S426P	Neutral	0.39
BRCA1	P38398-1.2	S426Q	Neutral	0.433
BRCA1	P38398-1.2	S426R	Pathogenic	0.697
BRCA1	P38398-1.2	S426T	Neutral	0.249
BRCA1	P38398-1.2	S426V	Pathogenic	0.559
BRCA1	P38398-1.2	S426W	Pathogenic	0.867
BRCA1	P38398-1.2	S426Y	Pathogenic	0.739
BRCA1	P38398-1.2	E427A	Neutral	0.27
BRCA1	P38398-1.2	E427C	Neutral	0.416
BRCA1	P38398-1.2	E427D	Neutral	0.069
BRCA1	P38398-1.2	E427F	Neutral	0.343
BRCA1	P38398-1.2	E427G	Neutral	0.449
BRCA1	P38398-1.2	E427H	Neutral	0.11
BRCA1	P38398-1.2	E427I	Neutral	0.29
BRCA1	P38398-1.2	E427K	Neutral	0.112
BRCA1	P38398-1.2	E427L	Neutral	0.29
BRCA1	P38398-1.2	E427M	Neutral	0.223
BRCA1	P38398-1.2	E427N	Neutral	0.121
BRCA1	P38398-1.2	E427P	Neutral	0.18
BRCA1	P38398-1.2	E427Q	Neutral	0.052
BRCA1	P38398-1.2	E427R	Neutral	0.195
BRCA1	P38398-1.2	E427S	Neutral	0.184
BRCA1	P38398-1.2	E427T	Neutral	0.172
BRCA1	P38398-1.2	E427V	Neutral	0.183
BRCA1	P38398-1.2	E427W	Neutral	0.49
BRCA1	P38398-1.2	E427Y	Neutral	0.296
BRCA1	P38398-1.2	K428A	Pathogenic	0.976
BRCA1	P38398-1.2	K428C	Pathogenic	0.982
BRCA1	P38398-1.2	K428D	Pathogenic	0.961
BRCA1	P38398-1.2	K428E	Pathogenic	0.888
BRCA1	P38398-1.2	K428F	Pathogenic	0.948
BRCA1	P38398-1.2	K428G	Pathogenic	0.989
BRCA1	P38398-1.2	K428H	Pathogenic	0.93
BRCA1	P38398-1.2	K428I	Pathogenic	0.959
BRCA1	P38398-1.2	K428L	Pathogenic	0.942
BRCA1	P38398-1.2	K428M	Pathogenic	0.919
BRCA1	P38398-1.2	K428N	Pathogenic	0.939
BRCA1	P38398-1.2	K428P	Pathogenic	0.961
BRCA1	P38398-1.2	K428Q	Pathogenic	0.876
BRCA1	P38398-1.2	K428R	Pathogenic	0.807
BRCA1	P38398-1.2	K428S	Pathogenic	0.962
BRCA1	P38398-1.2	K428T	Pathogenic	0.959
BRCA1	P38398-1.2	K428V	Pathogenic	0.962
BRCA1	P38398-1.2	K428W	Pathogenic	0.971
BRCA1	P38398-1.2	K428Y	Pathogenic	0.937
BRCA1	P38398-1.2	I429A	Pathogenic	0.837
BRCA1	P38398-1.2	I429C	Pathogenic	0.773
BRCA1	P38398-1.2	I429D	Pathogenic	0.859
BRCA1	P38398-1.2	I429E	Pathogenic	0.804
BRCA1	P38398-1.2	I429F	Pathogenic	0.569
BRCA1	P38398-1.2	I429G	Pathogenic	0.959
BRCA1	P38398-1.2	I429H	Pathogenic	0.773
BRCA1	P38398-1.2	I429K	Pathogenic	0.788
BRCA1	P38398-1.2	I429L	Neutral	0.333
BRCA1	P38398-1.2	I429M	Neutral	0.415
BRCA1	P38398-1.2	I429N	Pathogenic	0.846
BRCA1	P38398-1.2	I429P	Pathogenic	0.865
BRCA1	P38398-1.2	I429Q	Pathogenic	0.787
BRCA1	P38398-1.2	I429R	Pathogenic	0.833
BRCA1	P38398-1.2	I429S	Pathogenic	0.865
BRCA1	P38398-1.2	I429T	Pathogenic	0.742
BRCA1	P38398-1.2	I429V	Neutral	0.343
BRCA1	P38398-1.2	I429W	Pathogenic	0.879
BRCA1	P38398-1.2	I429Y	Pathogenic	0.681
BRCA1	P38398-1.2	D430A	Neutral	0.271
BRCA1	P38398-1.2	D430C	Neutral	0.257
BRCA1	P38398-1.2	D430E	Neutral	0.072
BRCA1	P38398-1.2	D430F	Neutral	0.448
BRCA1	P38398-1.2	D430G	Neutral	0.284
BRCA1	P38398-1.2	D430H	Neutral	0.217
BRCA1	P38398-1.2	D430I	Neutral	0.388
BRCA1	P38398-1.2	D430K	Neutral	0.29
BRCA1	P38398-1.2	D430L	Neutral	0.478
BRCA1	P38398-1.2	D430M	Neutral	0.391
BRCA1	P38398-1.2	D430N	Neutral	0.077
BRCA1	P38398-1.2	D430P	Neutral	0.133
BRCA1	P38398-1.2	D430Q	Neutral	0.151
BRCA1	P38398-1.2	D430R	Neutral	0.44
BRCA1	P38398-1.2	D430S	Neutral	0.137
BRCA1	P38398-1.2	D430T	Neutral	0.137
BRCA1	P38398-1.2	D430V	Neutral	0.296
BRCA1	P38398-1.2	D430W	Pathogenic	0.683
BRCA1	P38398-1.2	D430Y	Neutral	0.485
BRCA1	P38398-1.2	L431A	Pathogenic	0.89
BRCA1	P38398-1.2	L431C	Pathogenic	0.843
BRCA1	P38398-1.2	L431D	Pathogenic	0.933
BRCA1	P38398-1.2	L431E	Pathogenic	0.866
BRCA1	P38398-1.2	L431F	Pathogenic	0.675
BRCA1	P38398-1.2	L431G	Pathogenic	0.973
BRCA1	P38398-1.2	L431H	Pathogenic	0.843
BRCA1	P38398-1.2	L431I	Neutral	0.44
BRCA1	P38398-1.2	L431K	Pathogenic	0.804
BRCA1	P38398-1.2	L431M	Neutral	0.438
BRCA1	P38398-1.2	L431N	Pathogenic	0.896
BRCA1	P38398-1.2	L431P	Pathogenic	0.91
BRCA1	P38398-1.2	L431Q	Pathogenic	0.802
BRCA1	P38398-1.2	L431R	Pathogenic	0.845
BRCA1	P38398-1.2	L431S	Pathogenic	0.91
BRCA1	P38398-1.2	L431T	Pathogenic	0.819
BRCA1	P38398-1.2	L431V	Pathogenic	0.631
BRCA1	P38398-1.2	L431W	Pathogenic	0.888
BRCA1	P38398-1.2	L431Y	Pathogenic	0.771
BRCA1	P38398-1.2	L432A	Neutral	0.082
BRCA1	P38398-1.2	L432C	Neutral	0.056
BRCA1	P38398-1.2	L432D	Neutral	0.132
BRCA1	P38398-1.2	L432E	Neutral	0.067
BRCA1	P38398-1.2	L432F	Neutral	0.022
BRCA1	P38398-1.2	L432G	Neutral	0.287
BRCA1	P38398-1.2	L432H	Neutral	0.056
BRCA1	P38398-1.2	L432I	Neutral	0.009
BRCA1	P38398-1.2	L432K	Neutral	0.043
BRCA1	P38398-1.2	L432M	Neutral	0.009
BRCA1	P38398-1.2	L432N	Neutral	0.087
BRCA1	P38398-1.2	L432P	Neutral	0.1
BRCA1	P38398-1.2	L432Q	Neutral	0.043
BRCA1	P38398-1.2	L432R	Neutral	0.057
BRCA1	P38398-1.2	L432S	Neutral	0.1
BRCA1	P38398-1.2	L432T	Neutral	0.048
BRCA1	P38398-1.2	L432V	Neutral	0.018
BRCA1	P38398-1.2	L432W	Neutral	0.08
BRCA1	P38398-1.2	L432Y	Neutral	0.036
BRCA1	P38398-1.2	A433C	Pathogenic	0.855
BRCA1	P38398-1.2	A433D	Pathogenic	0.931
BRCA1	P38398-1.2	A433E	Pathogenic	0.934
BRCA1	P38398-1.2	A433F	Pathogenic	0.973
BRCA1	P38398-1.2	A433G	Pathogenic	0.856
BRCA1	P38398-1.2	A433H	Pathogenic	0.962
BRCA1	P38398-1.2	A433I	Pathogenic	0.951
BRCA1	P38398-1.2	A433K	Pathogenic	0.961
BRCA1	P38398-1.2	A433L	Pathogenic	0.951
BRCA1	P38398-1.2	A433M	Pathogenic	0.952
BRCA1	P38398-1.2	A433N	Pathogenic	0.938
BRCA1	P38398-1.2	A433P	Pathogenic	0.903
BRCA1	P38398-1.2	A433Q	Pathogenic	0.941
BRCA1	P38398-1.2	A433R	Pathogenic	0.971
BRCA1	P38398-1.2	A433S	Pathogenic	0.755
BRCA1	P38398-1.2	A433T	Pathogenic	0.875
BRCA1	P38398-1.2	A433V	Pathogenic	0.9
BRCA1	P38398-1.2	A433W	Pathogenic	0.99
BRCA1	P38398-1.2	A433Y	Pathogenic	0.976
BRCA1	P38398-1.2	S434A	Neutral	0.009
BRCA1	P38398-1.2	S434C	Neutral	0.022
BRCA1	P38398-1.2	S434D	Neutral	0.017
BRCA1	P38398-1.2	S434E	Neutral	0.025
BRCA1	P38398-1.2	S434F	Neutral	0.086
BRCA1	P38398-1.2	S434G	Neutral	0.02
BRCA1	P38398-1.2	S434H	Neutral	0.044
BRCA1	P38398-1.2	S434I	Neutral	0.069
BRCA1	P38398-1.2	S434K	Neutral	0.044
BRCA1	P38398-1.2	S434L	Neutral	0.069
BRCA1	P38398-1.2	S434M	Neutral	0.049
BRCA1	P38398-1.2	S434N	Neutral	0.013
BRCA1	P38398-1.2	S434P	Neutral	0.024
BRCA1	P38398-1.2	S434Q	Neutral	0.029
BRCA1	P38398-1.2	S434R	Neutral	0.081
BRCA1	P38398-1.2	S434T	Neutral	0.013
BRCA1	P38398-1.2	S434V	Neutral	0.047
BRCA1	P38398-1.2	S434W	Neutral	0.2
BRCA1	P38398-1.2	S434Y	Neutral	0.098
BRCA1	P38398-1.2	D435A	Neutral	0.341
BRCA1	P38398-1.2	D435C	Neutral	0.325
BRCA1	P38398-1.2	D435E	Neutral	0.097
BRCA1	P38398-1.2	D435F	Pathogenic	0.53
BRCA1	P38398-1.2	D435G	Neutral	0.355
BRCA1	P38398-1.2	D435H	Neutral	0.278
BRCA1	P38398-1.2	D435I	Neutral	0.469
BRCA1	P38398-1.2	D435K	Neutral	0.363
BRCA1	P38398-1.2	D435L	Pathogenic	0.56
BRCA1	P38398-1.2	D435M	Neutral	0.472
BRCA1	P38398-1.2	D435N	Neutral	0.104
BRCA1	P38398-1.2	D435P	Neutral	0.176
BRCA1	P38398-1.2	D435Q	Neutral	0.198
BRCA1	P38398-1.2	D435R	Pathogenic	0.522
BRCA1	P38398-1.2	D435S	Neutral	0.18
BRCA1	P38398-1.2	D435T	Neutral	0.181
BRCA1	P38398-1.2	D435V	Neutral	0.369
BRCA1	P38398-1.2	D435W	Pathogenic	0.75
BRCA1	P38398-1.2	D435Y	Pathogenic	0.567
BRCA1	P38398-1.2	P436A	Pathogenic	0.74
BRCA1	P38398-1.2	P436C	Pathogenic	0.795
BRCA1	P38398-1.2	P436D	Pathogenic	0.632
BRCA1	P38398-1.2	P436E	Pathogenic	0.719
BRCA1	P38398-1.2	P436F	Pathogenic	0.932
BRCA1	P38398-1.2	P436G	Pathogenic	0.862
BRCA1	P38398-1.2	P436H	Pathogenic	0.821
BRCA1	P38398-1.2	P436I	Pathogenic	0.882
BRCA1	P38398-1.2	P436K	Pathogenic	0.819
BRCA1	P38398-1.2	P436L	Pathogenic	0.882
BRCA1	P38398-1.2	P436M	Pathogenic	0.84
BRCA1	P38398-1.2	P436N	Pathogenic	0.734
BRCA1	P38398-1.2	P436Q	Pathogenic	0.743
BRCA1	P38398-1.2	P436R	Pathogenic	0.897
BRCA1	P38398-1.2	P436S	Pathogenic	0.713
BRCA1	P38398-1.2	P436T	Pathogenic	0.646
BRCA1	P38398-1.2	P436V	Pathogenic	0.774
BRCA1	P38398-1.2	P436W	Pathogenic	0.962
BRCA1	P38398-1.2	P436Y	Pathogenic	0.917
BRCA1	P38398-1.2	H437A	Neutral	0.223
BRCA1	P38398-1.2	H437C	Neutral	0.211
BRCA1	P38398-1.2	H437D	Neutral	0.103
BRCA1	P38398-1.2	H437E	Neutral	0.051
BRCA1	P38398-1.2	H437F	Neutral	0.083
BRCA1	P38398-1.2	H437G	Neutral	0.304
BRCA1	P38398-1.2	H437I	Neutral	0.128
BRCA1	P38398-1.2	H437K	Neutral	0.084
BRCA1	P38398-1.2	H437L	Neutral	0.129
BRCA1	P38398-1.2	H437M	Neutral	0.094
BRCA1	P38398-1.2	H437N	Neutral	0.048
BRCA1	P38398-1.2	H437P	Neutral	0.146
BRCA1	P38398-1.2	H437Q	Neutral	0.046
BRCA1	P38398-1.2	H437R	Neutral	0.078
BRCA1	P38398-1.2	H437S	Neutral	0.148
BRCA1	P38398-1.2	H437T	Neutral	0.139
BRCA1	P38398-1.2	H437V	Neutral	0.148
BRCA1	P38398-1.2	H437W	Neutral	0.195
BRCA1	P38398-1.2	H437Y	Neutral	0.034
BRCA1	P38398-1.2	E438A	Neutral	0.001
BRCA1	P38398-1.2	E438C	Neutral	0.002
BRCA1	P38398-1.2	E438D	Neutral	0.0
BRCA1	P38398-1.2	E438F	Neutral	0.001
BRCA1	P38398-1.2	E438G	Neutral	0.002
BRCA1	P38398-1.2	E438H	Neutral	0.0
BRCA1	P38398-1.2	E438I	Neutral	0.001
BRCA1	P38398-1.2	E438K	Neutral	0.0
BRCA1	P38398-1.2	E438L	Neutral	0.001
BRCA1	P38398-1.2	E438M	Neutral	0.001
BRCA1	P38398-1.2	E438N	Neutral	0.0
BRCA1	P38398-1.2	E438P	Neutral	0.0
BRCA1	P38398-1.2	E438Q	Neutral	0.0
BRCA1	P38398-1.2	E438R	Neutral	0.001
BRCA1	P38398-1.2	E438S	Neutral	0.0
BRCA1	P38398-1.2	E438T	Neutral	0.0
BRCA1	P38398-1.2	E438V	Neutral	0.0
BRCA1	P38398-1.2	E438W	Neutral	0.002
BRCA1	P38398-1.2	E438Y	Neutral	0.001
BRCA1	P38398-1.2	A439C	Neutral	0.082
BRCA1	P38398-1.2	A439D	Neutral	0.171
BRCA1	P38398-1.2	A439E	Neutral	0.176
BRCA1	P38398-1.2	A439F	Neutral	0.352
BRCA1	P38398-1.2	A439G	Neutral	0.083
BRCA1	P38398-1.2	A439H	Neutral	0.276
BRCA1	P38398-1.2	A439I	Neutral	0.228
BRCA1	P38398-1.2	A439K	Neutral	0.274
BRCA1	P38398-1.2	A439L	Neutral	0.228
BRCA1	P38398-1.2	A439M	Neutral	0.23
BRCA1	P38398-1.2	A439N	Neutral	0.187
BRCA1	P38398-1.2	A439P	Neutral	0.124
BRCA1	P38398-1.2	A439Q	Neutral	0.194
BRCA1	P38398-1.2	A439R	Neutral	0.335
BRCA1	P38398-1.2	A439S	Neutral	0.045
BRCA1	P38398-1.2	A439T	Neutral	0.096
BRCA1	P38398-1.2	A439V	Neutral	0.12
BRCA1	P38398-1.2	A439W	Pathogenic	0.59
BRCA1	P38398-1.2	A439Y	Neutral	0.386
BRCA1	P38398-1.2	L440A	Neutral	0.427
BRCA1	P38398-1.2	L440C	Neutral	0.331
BRCA1	P38398-1.2	L440D	Pathogenic	0.561
BRCA1	P38398-1.2	L440E	Neutral	0.374
BRCA1	P38398-1.2	L440F	Neutral	0.161
BRCA1	P38398-1.2	L440G	Pathogenic	0.771
BRCA1	P38398-1.2	L440H	Neutral	0.332
BRCA1	P38398-1.2	L440I	Neutral	0.067
BRCA1	P38398-1.2	L440K	Neutral	0.274
BRCA1	P38398-1.2	L440M	Neutral	0.067
BRCA1	P38398-1.2	L440N	Neutral	0.444
BRCA1	P38398-1.2	L440P	Neutral	0.483
BRCA1	P38398-1.2	L440Q	Neutral	0.272
BRCA1	P38398-1.2	L440R	Neutral	0.335
BRCA1	P38398-1.2	L440S	Neutral	0.483
BRCA1	P38398-1.2	L440T	Neutral	0.295
BRCA1	P38398-1.2	L440V	Neutral	0.136
BRCA1	P38398-1.2	L440W	Neutral	0.422
BRCA1	P38398-1.2	L440Y	Neutral	0.237
BRCA1	P38398-1.2	I441A	Neutral	0.019
BRCA1	P38398-1.2	I441C	Neutral	0.013
BRCA1	P38398-1.2	I441D	Neutral	0.022
BRCA1	P38398-1.2	I441E	Neutral	0.015
BRCA1	P38398-1.2	I441F	Neutral	0.005
BRCA1	P38398-1.2	I441G	Neutral	0.08
BRCA1	P38398-1.2	I441H	Neutral	0.013
BRCA1	P38398-1.2	I441K	Neutral	0.014
BRCA1	P38398-1.2	I441L	Neutral	0.002
BRCA1	P38398-1.2	I441M	Neutral	0.003
BRCA1	P38398-1.2	I441N	Neutral	0.02
BRCA1	P38398-1.2	I441P	Neutral	0.023
BRCA1	P38398-1.2	I441Q	Neutral	0.014
BRCA1	P38398-1.2	I441R	Neutral	0.018
BRCA1	P38398-1.2	I441S	Neutral	0.023
BRCA1	P38398-1.2	I441T	Neutral	0.011
BRCA1	P38398-1.2	I441V	Neutral	0.002
BRCA1	P38398-1.2	I441W	Neutral	0.026
BRCA1	P38398-1.2	I441Y	Neutral	0.008
BRCA1	P38398-1.2	C442A	Neutral	0.042
BRCA1	P38398-1.2	C442D	Neutral	0.086
BRCA1	P38398-1.2	C442E	Neutral	0.169
BRCA1	P38398-1.2	C442F	Neutral	0.151
BRCA1	P38398-1.2	C442G	Neutral	0.166
BRCA1	P38398-1.2	C442H	Neutral	0.149
BRCA1	P38398-1.2	C442I	Neutral	0.088
BRCA1	P38398-1.2	C442K	Neutral	0.2
BRCA1	P38398-1.2	C442L	Neutral	0.088
BRCA1	P38398-1.2	C442M	Neutral	0.089
BRCA1	P38398-1.2	C442N	Neutral	0.096
BRCA1	P38398-1.2	C442P	Neutral	0.087
BRCA1	P38398-1.2	C442Q	Neutral	0.137
BRCA1	P38398-1.2	C442R	Neutral	0.25
BRCA1	P38398-1.2	C442S	Neutral	0.052
BRCA1	P38398-1.2	C442T	Neutral	0.046
BRCA1	P38398-1.2	C442V	Neutral	0.06
BRCA1	P38398-1.2	C442W	Neutral	0.247
BRCA1	P38398-1.2	C442Y	Neutral	0.171
BRCA1	P38398-1.2	K443A	Neutral	0.013
BRCA1	P38398-1.2	K443C	Neutral	0.017
BRCA1	P38398-1.2	K443D	Neutral	0.008
BRCA1	P38398-1.2	K443E	Neutral	0.003
BRCA1	P38398-1.2	K443F	Neutral	0.006
BRCA1	P38398-1.2	K443G	Neutral	0.028
BRCA1	P38398-1.2	K443H	Neutral	0.004
BRCA1	P38398-1.2	K443I	Neutral	0.007
BRCA1	P38398-1.2	K443L	Neutral	0.005
BRCA1	P38398-1.2	K443M	Neutral	0.004
BRCA1	P38398-1.2	K443N	Neutral	0.005
BRCA1	P38398-1.2	K443P	Neutral	0.008
BRCA1	P38398-1.2	K443Q	Neutral	0.002
BRCA1	P38398-1.2	K443R	Neutral	0.001
BRCA1	P38398-1.2	K443S	Neutral	0.008
BRCA1	P38398-1.2	K443T	Neutral	0.007
BRCA1	P38398-1.2	K443V	Neutral	0.008
BRCA1	P38398-1.2	K443W	Neutral	0.011
BRCA1	P38398-1.2	K443Y	Neutral	0.005
BRCA1	P38398-1.2	S444A	Neutral	0.05
BRCA1	P38398-1.2	S444C	Neutral	0.111
BRCA1	P38398-1.2	S444D	Neutral	0.089
BRCA1	P38398-1.2	S444E	Neutral	0.127
BRCA1	P38398-1.2	S444F	Neutral	0.345
BRCA1	P38398-1.2	S444G	Neutral	0.104
BRCA1	P38398-1.2	S444H	Neutral	0.206
BRCA1	P38398-1.2	S444I	Neutral	0.292
BRCA1	P38398-1.2	S444K	Neutral	0.205
BRCA1	P38398-1.2	S444L	Neutral	0.292
BRCA1	P38398-1.2	S444M	Neutral	0.225
BRCA1	P38398-1.2	S444N	Neutral	0.071
BRCA1	P38398-1.2	S444P	Neutral	0.121
BRCA1	P38398-1.2	S444Q	Neutral	0.141
BRCA1	P38398-1.2	S444R	Neutral	0.332
BRCA1	P38398-1.2	S444T	Neutral	0.067
BRCA1	P38398-1.2	S444V	Neutral	0.215
BRCA1	P38398-1.2	S444W	Pathogenic	0.583
BRCA1	P38398-1.2	S444Y	Neutral	0.379
BRCA1	P38398-1.2	E445A	Pathogenic	0.626
BRCA1	P38398-1.2	E445C	Pathogenic	0.763
BRCA1	P38398-1.2	E445D	Neutral	0.251
BRCA1	P38398-1.2	E445F	Pathogenic	0.702
BRCA1	P38398-1.2	E445G	Pathogenic	0.787
BRCA1	P38398-1.2	E445H	Neutral	0.359
BRCA1	P38398-1.2	E445I	Pathogenic	0.649
BRCA1	P38398-1.2	E445K	Neutral	0.364
BRCA1	P38398-1.2	E445L	Pathogenic	0.649
BRCA1	P38398-1.2	E445M	Pathogenic	0.565
BRCA1	P38398-1.2	E445N	Neutral	0.383
BRCA1	P38398-1.2	E445P	Neutral	0.499
BRCA1	P38398-1.2	E445Q	Neutral	0.199
BRCA1	P38398-1.2	E445R	Pathogenic	0.524
BRCA1	P38398-1.2	E445S	Pathogenic	0.506
BRCA1	P38398-1.2	E445T	Neutral	0.484
BRCA1	P38398-1.2	E445V	Pathogenic	0.504
BRCA1	P38398-1.2	E445W	Pathogenic	0.813
BRCA1	P38398-1.2	E445Y	Pathogenic	0.655
BRCA1	P38398-1.2	R446A	Pathogenic	0.834
BRCA1	P38398-1.2	R446C	Pathogenic	0.871
BRCA1	P38398-1.2	R446D	Pathogenic	0.813
BRCA1	P38398-1.2	R446E	Pathogenic	0.583
BRCA1	P38398-1.2	R446F	Pathogenic	0.691
BRCA1	P38398-1.2	R446G	Pathogenic	0.917
BRCA1	P38398-1.2	R446H	Pathogenic	0.531
BRCA1	P38398-1.2	R446I	Pathogenic	0.741
BRCA1	P38398-1.2	R446K	Neutral	0.277
BRCA1	P38398-1.2	R446L	Pathogenic	0.665
BRCA1	P38398-1.2	R446M	Pathogenic	0.582
BRCA1	P38398-1.2	R446N	Pathogenic	0.651
BRCA1	P38398-1.2	R446P	Pathogenic	0.812
BRCA1	P38398-1.2	R446Q	Neutral	0.464
BRCA1	P38398-1.2	R446S	Pathogenic	0.816
BRCA1	P38398-1.2	R446T	Pathogenic	0.739
BRCA1	P38398-1.2	R446V	Pathogenic	0.815
BRCA1	P38398-1.2	R446W	Pathogenic	0.699
BRCA1	P38398-1.2	R446Y	Pathogenic	0.58
BRCA1	P38398-1.2	V447A	Neutral	0.039
BRCA1	P38398-1.2	V447C	Neutral	0.037
BRCA1	P38398-1.2	V447D	Neutral	0.065
BRCA1	P38398-1.2	V447E	Neutral	0.037
BRCA1	P38398-1.2	V447F	Neutral	0.047
BRCA1	P38398-1.2	V447G	Neutral	0.154
BRCA1	P38398-1.2	V447H	Neutral	0.064
BRCA1	P38398-1.2	V447I	Neutral	0.009
BRCA1	P38398-1.2	V447K	Neutral	0.064
BRCA1	P38398-1.2	V447L	Neutral	0.018
BRCA1	P38398-1.2	V447M	Neutral	0.018
BRCA1	P38398-1.2	V447N	Neutral	0.059
BRCA1	P38398-1.2	V447P	Neutral	0.048
BRCA1	P38398-1.2	V447Q	Neutral	0.042
BRCA1	P38398-1.2	V447R	Neutral	0.116
BRCA1	P38398-1.2	V447S	Neutral	0.068
BRCA1	P38398-1.2	V447T	Neutral	0.022
BRCA1	P38398-1.2	V447W	Neutral	0.158
BRCA1	P38398-1.2	V447Y	Neutral	0.053
BRCA1	P38398-1.2	H448A	Neutral	0.036
BRCA1	P38398-1.2	H448C	Neutral	0.033
BRCA1	P38398-1.2	H448D	Neutral	0.015
BRCA1	P38398-1.2	H448E	Neutral	0.007
BRCA1	P38398-1.2	H448F	Neutral	0.012
BRCA1	P38398-1.2	H448G	Neutral	0.053
BRCA1	P38398-1.2	H448I	Neutral	0.019
BRCA1	P38398-1.2	H448K	Neutral	0.012
BRCA1	P38398-1.2	H448L	Neutral	0.019
BRCA1	P38398-1.2	H448M	Neutral	0.013
BRCA1	P38398-1.2	H448N	Neutral	0.006
BRCA1	P38398-1.2	H448P	Neutral	0.021
BRCA1	P38398-1.2	H448Q	Neutral	0.006
BRCA1	P38398-1.2	H448R	Neutral	0.011
BRCA1	P38398-1.2	H448S	Neutral	0.022
BRCA1	P38398-1.2	H448T	Neutral	0.02
BRCA1	P38398-1.2	H448V	Neutral	0.022
BRCA1	P38398-1.2	H448W	Neutral	0.03
BRCA1	P38398-1.2	H448Y	Neutral	0.005
BRCA1	P38398-1.2	S449A	Neutral	0.011
BRCA1	P38398-1.2	S449C	Neutral	0.027
BRCA1	P38398-1.2	S449D	Neutral	0.021
BRCA1	P38398-1.2	S449E	Neutral	0.031
BRCA1	P38398-1.2	S449F	Neutral	0.104
BRCA1	P38398-1.2	S449G	Neutral	0.025
BRCA1	P38398-1.2	S449H	Neutral	0.054
BRCA1	P38398-1.2	S449I	Neutral	0.083
BRCA1	P38398-1.2	S449K	Neutral	0.054
BRCA1	P38398-1.2	S449L	Neutral	0.083
BRCA1	P38398-1.2	S449M	Neutral	0.06
BRCA1	P38398-1.2	S449N	Neutral	0.016
BRCA1	P38398-1.2	S449P	Neutral	0.029
BRCA1	P38398-1.2	S449Q	Neutral	0.035
BRCA1	P38398-1.2	S449R	Neutral	0.099
BRCA1	P38398-1.2	S449T	Neutral	0.016
BRCA1	P38398-1.2	S449V	Neutral	0.057
BRCA1	P38398-1.2	S449W	Neutral	0.236
BRCA1	P38398-1.2	S449Y	Neutral	0.119
BRCA1	P38398-1.2	K450A	Pathogenic	0.929
BRCA1	P38398-1.2	K450C	Pathogenic	0.946
BRCA1	P38398-1.2	K450D	Pathogenic	0.887
BRCA1	P38398-1.2	K450E	Pathogenic	0.717
BRCA1	P38398-1.2	K450F	Pathogenic	0.854
BRCA1	P38398-1.2	K450G	Pathogenic	0.967
BRCA1	P38398-1.2	K450H	Pathogenic	0.809
BRCA1	P38398-1.2	K450I	Pathogenic	0.882
BRCA1	P38398-1.2	K450L	Pathogenic	0.838
BRCA1	P38398-1.2	K450M	Pathogenic	0.784
BRCA1	P38398-1.2	K450N	Pathogenic	0.83
BRCA1	P38398-1.2	K450P	Pathogenic	0.887
BRCA1	P38398-1.2	K450Q	Pathogenic	0.693
BRCA1	P38398-1.2	K450R	Pathogenic	0.571
BRCA1	P38398-1.2	K450S	Pathogenic	0.889
BRCA1	P38398-1.2	K450T	Pathogenic	0.881
BRCA1	P38398-1.2	K450V	Pathogenic	0.889
BRCA1	P38398-1.2	K450W	Pathogenic	0.915
BRCA1	P38398-1.2	K450Y	Pathogenic	0.825
BRCA1	P38398-1.2	S451A	Neutral	0.004
BRCA1	P38398-1.2	S451C	Neutral	0.009
BRCA1	P38398-1.2	S451D	Neutral	0.007
BRCA1	P38398-1.2	S451E	Neutral	0.011
BRCA1	P38398-1.2	S451F	Neutral	0.037
BRCA1	P38398-1.2	S451G	Neutral	0.008
BRCA1	P38398-1.2	S451H	Neutral	0.019
BRCA1	P38398-1.2	S451I	Neutral	0.029
BRCA1	P38398-1.2	S451K	Neutral	0.019
BRCA1	P38398-1.2	S451L	Neutral	0.029
BRCA1	P38398-1.2	S451M	Neutral	0.021
BRCA1	P38398-1.2	S451N	Neutral	0.006
BRCA1	P38398-1.2	S451P	Neutral	0.01
BRCA1	P38398-1.2	S451Q	Neutral	0.012
BRCA1	P38398-1.2	S451R	Neutral	0.035
BRCA1	P38398-1.2	S451T	Neutral	0.005
BRCA1	P38398-1.2	S451V	Neutral	0.02
BRCA1	P38398-1.2	S451W	Neutral	0.093
BRCA1	P38398-1.2	S451Y	Neutral	0.043
BRCA1	P38398-1.2	V452A	Neutral	0.231
BRCA1	P38398-1.2	V452C	Neutral	0.224
BRCA1	P38398-1.2	V452D	Neutral	0.34
BRCA1	P38398-1.2	V452E	Neutral	0.223
BRCA1	P38398-1.2	V452F	Neutral	0.267
BRCA1	P38398-1.2	V452G	Pathogenic	0.576
BRCA1	P38398-1.2	V452H	Neutral	0.339
BRCA1	P38398-1.2	V452I	Neutral	0.062
BRCA1	P38398-1.2	V452K	Neutral	0.337
BRCA1	P38398-1.2	V452L	Neutral	0.122
BRCA1	P38398-1.2	V452M	Neutral	0.122
BRCA1	P38398-1.2	V452N	Neutral	0.317
BRCA1	P38398-1.2	V452P	Neutral	0.274
BRCA1	P38398-1.2	V452Q	Neutral	0.245
BRCA1	P38398-1.2	V452R	Neutral	0.494
BRCA1	P38398-1.2	V452S	Neutral	0.352
BRCA1	P38398-1.2	V452T	Neutral	0.144
BRCA1	P38398-1.2	V452W	Pathogenic	0.583
BRCA1	P38398-1.2	V452Y	Neutral	0.296
BRCA1	P38398-1.2	E453A	Neutral	0.217
BRCA1	P38398-1.2	E453C	Neutral	0.349
BRCA1	P38398-1.2	E453D	Neutral	0.053
BRCA1	P38398-1.2	E453F	Neutral	0.281
BRCA1	P38398-1.2	E453G	Neutral	0.38
BRCA1	P38398-1.2	E453H	Neutral	0.085
BRCA1	P38398-1.2	E453I	Neutral	0.235
BRCA1	P38398-1.2	E453K	Neutral	0.087
BRCA1	P38398-1.2	E453L	Neutral	0.235
BRCA1	P38398-1.2	E453M	Neutral	0.177
BRCA1	P38398-1.2	E453N	Neutral	0.093
BRCA1	P38398-1.2	E453P	Neutral	0.142
BRCA1	P38398-1.2	E453Q	Neutral	0.04
BRCA1	P38398-1.2	E453R	Neutral	0.154
BRCA1	P38398-1.2	E453S	Neutral	0.145
BRCA1	P38398-1.2	E453T	Neutral	0.135
BRCA1	P38398-1.2	E453V	Neutral	0.144
BRCA1	P38398-1.2	E453W	Neutral	0.42
BRCA1	P38398-1.2	E453Y	Neutral	0.24
BRCA1	P38398-1.2	S454A	Neutral	0.011
BRCA1	P38398-1.2	S454C	Neutral	0.026
BRCA1	P38398-1.2	S454D	Neutral	0.021
BRCA1	P38398-1.2	S454E	Neutral	0.031
BRCA1	P38398-1.2	S454F	Neutral	0.102
BRCA1	P38398-1.2	S454G	Neutral	0.024
BRCA1	P38398-1.2	S454H	Neutral	0.053
BRCA1	P38398-1.2	S454I	Neutral	0.082
BRCA1	P38398-1.2	S454K	Neutral	0.053
BRCA1	P38398-1.2	S454L	Neutral	0.082
BRCA1	P38398-1.2	S454M	Neutral	0.059
BRCA1	P38398-1.2	S454N	Neutral	0.016
BRCA1	P38398-1.2	S454P	Neutral	0.029
BRCA1	P38398-1.2	S454Q	Neutral	0.034
BRCA1	P38398-1.2	S454R	Neutral	0.097
BRCA1	P38398-1.2	S454T	Neutral	0.015
BRCA1	P38398-1.2	S454V	Neutral	0.056
BRCA1	P38398-1.2	S454W	Neutral	0.233
BRCA1	P38398-1.2	S454Y	Neutral	0.117
BRCA1	P38398-1.2	N455A	Neutral	0.371
BRCA1	P38398-1.2	N455C	Neutral	0.355
BRCA1	P38398-1.2	N455D	Neutral	0.105
BRCA1	P38398-1.2	N455E	Neutral	0.169
BRCA1	P38398-1.2	N455F	Pathogenic	0.508
BRCA1	P38398-1.2	N455G	Neutral	0.304
BRCA1	P38398-1.2	N455H	Neutral	0.145
BRCA1	P38398-1.2	N455I	Neutral	0.447
BRCA1	P38398-1.2	N455K	Neutral	0.264
BRCA1	P38398-1.2	N455L	Neutral	0.447
BRCA1	P38398-1.2	N455M	Neutral	0.362
BRCA1	P38398-1.2	N455P	Neutral	0.26
BRCA1	P38398-1.2	N455Q	Neutral	0.184
BRCA1	P38398-1.2	N455R	Neutral	0.324
BRCA1	P38398-1.2	N455S	Neutral	0.149
BRCA1	P38398-1.2	N455T	Neutral	0.138
BRCA1	P38398-1.2	N455V	Neutral	0.349
BRCA1	P38398-1.2	N455W	Pathogenic	0.733
BRCA1	P38398-1.2	N455Y	Neutral	0.454
BRCA1	P38398-1.2	I456A	Pathogenic	0.759
BRCA1	P38398-1.2	I456C	Pathogenic	0.676
BRCA1	P38398-1.2	I456D	Pathogenic	0.789
BRCA1	P38398-1.2	I456E	Pathogenic	0.715
BRCA1	P38398-1.2	I456F	Neutral	0.447
BRCA1	P38398-1.2	I456G	Pathogenic	0.934
BRCA1	P38398-1.2	I456H	Pathogenic	0.676
BRCA1	P38398-1.2	I456K	Pathogenic	0.696
BRCA1	P38398-1.2	I456L	Neutral	0.234
BRCA1	P38398-1.2	I456M	Neutral	0.303
BRCA1	P38398-1.2	I456N	Pathogenic	0.771
BRCA1	P38398-1.2	I456P	Pathogenic	0.797
BRCA1	P38398-1.2	I456Q	Pathogenic	0.694
BRCA1	P38398-1.2	I456R	Pathogenic	0.753
BRCA1	P38398-1.2	I456S	Pathogenic	0.797
BRCA1	P38398-1.2	I456T	Pathogenic	0.638
BRCA1	P38398-1.2	I456V	Neutral	0.243
BRCA1	P38398-1.2	I456W	Pathogenic	0.817
BRCA1	P38398-1.2	I456Y	Pathogenic	0.567
BRCA1	P38398-1.2	E457A	Neutral	0.319
BRCA1	P38398-1.2	E457C	Neutral	0.474
BRCA1	P38398-1.2	E457D	Neutral	0.086
BRCA1	P38398-1.2	E457F	Neutral	0.397
BRCA1	P38398-1.2	E457G	Pathogenic	0.508
BRCA1	P38398-1.2	E457H	Neutral	0.135
BRCA1	P38398-1.2	E457I	Neutral	0.341
BRCA1	P38398-1.2	E457K	Neutral	0.138
BRCA1	P38398-1.2	E457L	Neutral	0.341
BRCA1	P38398-1.2	E457M	Neutral	0.266
BRCA1	P38398-1.2	E457N	Neutral	0.148
BRCA1	P38398-1.2	E457P	Neutral	0.218
BRCA1	P38398-1.2	E457Q	Neutral	0.065
BRCA1	P38398-1.2	E457R	Neutral	0.235
BRCA1	P38398-1.2	E457S	Neutral	0.223
BRCA1	P38398-1.2	E457T	Neutral	0.208
BRCA1	P38398-1.2	E457V	Neutral	0.221
BRCA1	P38398-1.2	E457W	Pathogenic	0.549
BRCA1	P38398-1.2	E457Y	Neutral	0.347
BRCA1	P38398-1.2	D458A	Pathogenic	0.994
BRCA1	P38398-1.2	D458C	Pathogenic	0.993
BRCA1	P38398-1.2	D458E	Pathogenic	0.971
BRCA1	P38398-1.2	D458F	Pathogenic	0.997
BRCA1	P38398-1.2	D458G	Pathogenic	0.994
BRCA1	P38398-1.2	D458H	Pathogenic	0.992
BRCA1	P38398-1.2	D458I	Pathogenic	0.996
BRCA1	P38398-1.2	D458K	Pathogenic	0.994
BRCA1	P38398-1.2	D458L	Pathogenic	0.997
BRCA1	P38398-1.2	D458M	Pathogenic	0.996
BRCA1	P38398-1.2	D458N	Pathogenic	0.973
BRCA1	P38398-1.2	D458P	Pathogenic	0.985
BRCA1	P38398-1.2	D458Q	Pathogenic	0.987
BRCA1	P38398-1.2	D458R	Pathogenic	0.997
BRCA1	P38398-1.2	D458S	Pathogenic	0.986
BRCA1	P38398-1.2	D458T	Pathogenic	0.986
BRCA1	P38398-1.2	D458V	Pathogenic	0.995
BRCA1	P38398-1.2	D458W	Pathogenic	0.999
BRCA1	P38398-1.2	D458Y	Pathogenic	0.998
BRCA1	P38398-1.2	K459A	Pathogenic	0.977
BRCA1	P38398-1.2	K459C	Pathogenic	0.983
BRCA1	P38398-1.2	K459D	Pathogenic	0.962
BRCA1	P38398-1.2	K459E	Pathogenic	0.892
BRCA1	P38398-1.2	K459F	Pathogenic	0.95
BRCA1	P38398-1.2	K459G	Pathogenic	0.99
BRCA1	P38398-1.2	K459H	Pathogenic	0.933
BRCA1	P38398-1.2	K459I	Pathogenic	0.96
BRCA1	P38398-1.2	K459L	Pathogenic	0.944
BRCA1	P38398-1.2	K459M	Pathogenic	0.922
BRCA1	P38398-1.2	K459N	Pathogenic	0.941
BRCA1	P38398-1.2	K459P	Pathogenic	0.962
BRCA1	P38398-1.2	K459Q	Pathogenic	0.88
BRCA1	P38398-1.2	K459R	Pathogenic	0.813
BRCA1	P38398-1.2	K459S	Pathogenic	0.963
BRCA1	P38398-1.2	K459T	Pathogenic	0.96
BRCA1	P38398-1.2	K459V	Pathogenic	0.963
BRCA1	P38398-1.2	K459W	Pathogenic	0.972
BRCA1	P38398-1.2	K459Y	Pathogenic	0.939
BRCA1	P38398-1.2	I460A	Pathogenic	0.948
BRCA1	P38398-1.2	I460C	Pathogenic	0.923
BRCA1	P38398-1.2	I460D	Pathogenic	0.956
BRCA1	P38398-1.2	I460E	Pathogenic	0.935
BRCA1	P38398-1.2	I460F	Pathogenic	0.823
BRCA1	P38398-1.2	I460G	Pathogenic	0.988
BRCA1	P38398-1.2	I460H	Pathogenic	0.923
BRCA1	P38398-1.2	I460K	Pathogenic	0.929
BRCA1	P38398-1.2	I460L	Pathogenic	0.638
BRCA1	P38398-1.2	I460M	Pathogenic	0.715
BRCA1	P38398-1.2	I460N	Pathogenic	0.951
BRCA1	P38398-1.2	I460P	Pathogenic	0.958
BRCA1	P38398-1.2	I460Q	Pathogenic	0.929
BRCA1	P38398-1.2	I460R	Pathogenic	0.946
BRCA1	P38398-1.2	I460S	Pathogenic	0.958
BRCA1	P38398-1.2	I460T	Pathogenic	0.91
BRCA1	P38398-1.2	I460V	Pathogenic	0.649
BRCA1	P38398-1.2	I460W	Pathogenic	0.963
BRCA1	P38398-1.2	I460Y	Pathogenic	0.883
BRCA1	P38398-1.2	F461A	Pathogenic	0.998
BRCA1	P38398-1.2	F461C	Pathogenic	0.998
BRCA1	P38398-1.2	F461D	Pathogenic	0.998
BRCA1	P38398-1.2	F461E	Pathogenic	0.997
BRCA1	P38398-1.2	F461G	Pathogenic	0.999
BRCA1	P38398-1.2	F461H	Pathogenic	0.993
BRCA1	P38398-1.2	F461I	Pathogenic	0.989
BRCA1	P38398-1.2	F461K	Pathogenic	0.995
BRCA1	P38398-1.2	F461L	Pathogenic	0.989
BRCA1	P38398-1.2	F461M	Pathogenic	0.989
BRCA1	P38398-1.2	F461N	Pathogenic	0.998
BRCA1	P38398-1.2	F461P	Pathogenic	0.999
BRCA1	P38398-1.2	F461Q	Pathogenic	0.997
BRCA1	P38398-1.2	F461R	Pathogenic	0.996
BRCA1	P38398-1.2	F461S	Pathogenic	0.998
BRCA1	P38398-1.2	F461T	Pathogenic	0.997
BRCA1	P38398-1.2	F461V	Pathogenic	0.995
BRCA1	P38398-1.2	F461W	Pathogenic	0.989
BRCA1	P38398-1.2	F461Y	Pathogenic	0.963
BRCA1	P38398-1.2	G462A	Pathogenic	0.947
BRCA1	P38398-1.2	G462C	Pathogenic	0.988
BRCA1	P38398-1.2	G462D	Pathogenic	0.978
BRCA1	P38398-1.2	G462E	Pathogenic	0.989
BRCA1	P38398-1.2	G462F	Pathogenic	0.996
BRCA1	P38398-1.2	G462H	Pathogenic	0.991
BRCA1	P38398-1.2	G462I	Pathogenic	0.996
BRCA1	P38398-1.2	G462K	Pathogenic	0.994
BRCA1	P38398-1.2	G462L	Pathogenic	0.996
BRCA1	P38398-1.2	G462M	Pathogenic	0.995
BRCA1	P38398-1.2	G462N	Pathogenic	0.971
BRCA1	P38398-1.2	G462P	Pathogenic	0.984
BRCA1	P38398-1.2	G462Q	Pathogenic	0.991
BRCA1	P38398-1.2	G462R	Pathogenic	0.996
BRCA1	P38398-1.2	G462S	Pathogenic	0.954
BRCA1	P38398-1.2	G462T	Pathogenic	0.985
BRCA1	P38398-1.2	G462V	Pathogenic	0.992
BRCA1	P38398-1.2	G462W	Pathogenic	0.997
BRCA1	P38398-1.2	G462Y	Pathogenic	0.996
BRCA1	P38398-1.2	K463A	Pathogenic	0.982
BRCA1	P38398-1.2	K463C	Pathogenic	0.986
BRCA1	P38398-1.2	K463D	Pathogenic	0.97
BRCA1	P38398-1.2	K463E	Pathogenic	0.913
BRCA1	P38398-1.2	K463F	Pathogenic	0.96
BRCA1	P38398-1.2	K463G	Pathogenic	0.992
BRCA1	P38398-1.2	K463H	Pathogenic	0.946
BRCA1	P38398-1.2	K463I	Pathogenic	0.968
BRCA1	P38398-1.2	K463L	Pathogenic	0.955
BRCA1	P38398-1.2	K463M	Pathogenic	0.938
BRCA1	P38398-1.2	K463N	Pathogenic	0.953
BRCA1	P38398-1.2	K463P	Pathogenic	0.97
BRCA1	P38398-1.2	K463Q	Pathogenic	0.903
BRCA1	P38398-1.2	K463R	Pathogenic	0.846
BRCA1	P38398-1.2	K463S	Pathogenic	0.971
BRCA1	P38398-1.2	K463T	Pathogenic	0.968
BRCA1	P38398-1.2	K463V	Pathogenic	0.971
BRCA1	P38398-1.2	K463W	Pathogenic	0.978
BRCA1	P38398-1.2	K463Y	Pathogenic	0.951
BRCA1	P38398-1.2	T464A	Pathogenic	0.978
BRCA1	P38398-1.2	T464C	Pathogenic	0.976
BRCA1	P38398-1.2	T464D	Pathogenic	0.973
BRCA1	P38398-1.2	T464E	Pathogenic	0.98
BRCA1	P38398-1.2	T464F	Pathogenic	0.992
BRCA1	P38398-1.2	T464G	Pathogenic	0.993
BRCA1	P38398-1.2	T464H	Pathogenic	0.989
BRCA1	P38398-1.2	T464I	Pathogenic	0.986
BRCA1	P38398-1.2	T464K	Pathogenic	0.989
BRCA1	P38398-1.2	T464L	Pathogenic	0.986
BRCA1	P38398-1.2	T464M	Pathogenic	0.986
BRCA1	P38398-1.2	T464N	Pathogenic	0.963
BRCA1	P38398-1.2	T464P	Pathogenic	0.974
BRCA1	P38398-1.2	T464Q	Pathogenic	0.983
BRCA1	P38398-1.2	T464R	Pathogenic	0.992
BRCA1	P38398-1.2	T464S	Pathogenic	0.964
BRCA1	P38398-1.2	T464V	Pathogenic	0.97
BRCA1	P38398-1.2	T464W	Pathogenic	0.996
BRCA1	P38398-1.2	T464Y	Pathogenic	0.993
BRCA1	P38398-1.2	Y465A	Pathogenic	0.999
BRCA1	P38398-1.2	Y465C	Pathogenic	0.999
BRCA1	P38398-1.2	Y465D	Pathogenic	0.999
BRCA1	P38398-1.2	Y465E	Pathogenic	0.998
BRCA1	P38398-1.2	Y465F	Pathogenic	0.974
BRCA1	P38398-1.2	Y465G	Pathogenic	1.0
BRCA1	P38398-1.2	Y465H	Pathogenic	0.988
BRCA1	P38398-1.2	Y465I	Pathogenic	0.995
BRCA1	P38398-1.2	Y465K	Pathogenic	0.996
BRCA1	P38398-1.2	Y465L	Pathogenic	0.995
BRCA1	P38398-1.2	Y465M	Pathogenic	0.995
BRCA1	P38398-1.2	Y465N	Pathogenic	0.998
BRCA1	P38398-1.2	Y465P	Pathogenic	0.999
BRCA1	P38398-1.2	Y465Q	Pathogenic	0.996
BRCA1	P38398-1.2	Y465R	Pathogenic	0.996
BRCA1	P38398-1.2	Y465S	Pathogenic	0.999
BRCA1	P38398-1.2	Y465T	Pathogenic	0.998
BRCA1	P38398-1.2	Y465V	Pathogenic	0.997
BRCA1	P38398-1.2	Y465W	Pathogenic	0.987
BRCA1	P38398-1.2	R466A	Pathogenic	0.588
BRCA1	P38398-1.2	R466C	Pathogenic	0.657
BRCA1	P38398-1.2	R466D	Pathogenic	0.552
BRCA1	P38398-1.2	R466E	Neutral	0.284
BRCA1	P38398-1.2	R466F	Neutral	0.388
BRCA1	P38398-1.2	R466G	Pathogenic	0.759
BRCA1	P38398-1.2	R466H	Neutral	0.243
BRCA1	P38398-1.2	R466I	Neutral	0.448
BRCA1	P38398-1.2	R466K	Neutral	0.098
BRCA1	P38398-1.2	R466L	Neutral	0.361
BRCA1	P38398-1.2	R466M	Neutral	0.283
BRCA1	P38398-1.2	R466N	Neutral	0.347
BRCA1	P38398-1.2	R466P	Pathogenic	0.55
BRCA1	P38398-1.2	R466Q	Neutral	0.197
BRCA1	P38398-1.2	R466S	Pathogenic	0.557
BRCA1	P38398-1.2	R466T	Neutral	0.445
BRCA1	P38398-1.2	R466V	Pathogenic	0.555
BRCA1	P38398-1.2	R466W	Neutral	0.397
BRCA1	P38398-1.2	R466Y	Neutral	0.282
BRCA1	P38398-1.2	K467A	Pathogenic	0.933
BRCA1	P38398-1.2	K467C	Pathogenic	0.949
BRCA1	P38398-1.2	K467D	Pathogenic	0.893
BRCA1	P38398-1.2	K467E	Pathogenic	0.73
BRCA1	P38398-1.2	K467F	Pathogenic	0.861
BRCA1	P38398-1.2	K467G	Pathogenic	0.969
BRCA1	P38398-1.2	K467H	Pathogenic	0.819
BRCA1	P38398-1.2	K467I	Pathogenic	0.888
BRCA1	P38398-1.2	K467L	Pathogenic	0.847
BRCA1	P38398-1.2	K467M	Pathogenic	0.795
BRCA1	P38398-1.2	K467N	Pathogenic	0.838
BRCA1	P38398-1.2	K467P	Pathogenic	0.893
BRCA1	P38398-1.2	K467Q	Pathogenic	0.706
BRCA1	P38398-1.2	K467R	Pathogenic	0.586
BRCA1	P38398-1.2	K467S	Pathogenic	0.895
BRCA1	P38398-1.2	K467T	Pathogenic	0.887
BRCA1	P38398-1.2	K467V	Pathogenic	0.895
BRCA1	P38398-1.2	K467W	Pathogenic	0.92
BRCA1	P38398-1.2	K467Y	Pathogenic	0.834
BRCA1	P38398-1.2	K468A	Pathogenic	0.993
BRCA1	P38398-1.2	K468C	Pathogenic	0.995
BRCA1	P38398-1.2	K468D	Pathogenic	0.989
BRCA1	P38398-1.2	K468E	Pathogenic	0.965
BRCA1	P38398-1.2	K468F	Pathogenic	0.985
BRCA1	P38398-1.2	K468G	Pathogenic	0.997
BRCA1	P38398-1.2	K468H	Pathogenic	0.979
BRCA1	P38398-1.2	K468I	Pathogenic	0.988
BRCA1	P38398-1.2	K468L	Pathogenic	0.983
BRCA1	P38398-1.2	K468M	Pathogenic	0.976
BRCA1	P38398-1.2	K468N	Pathogenic	0.982
BRCA1	P38398-1.2	K468P	Pathogenic	0.988
BRCA1	P38398-1.2	K468Q	Pathogenic	0.961
BRCA1	P38398-1.2	K468R	Pathogenic	0.936
BRCA1	P38398-1.2	K468S	Pathogenic	0.989
BRCA1	P38398-1.2	K468T	Pathogenic	0.988
BRCA1	P38398-1.2	K468V	Pathogenic	0.989
BRCA1	P38398-1.2	K468W	Pathogenic	0.992
BRCA1	P38398-1.2	K468Y	Pathogenic	0.981
BRCA1	P38398-1.2	A469C	Neutral	0.031
BRCA1	P38398-1.2	A469D	Neutral	0.068
BRCA1	P38398-1.2	A469E	Neutral	0.071
BRCA1	P38398-1.2	A469F	Neutral	0.162
BRCA1	P38398-1.2	A469G	Neutral	0.031
BRCA1	P38398-1.2	A469H	Neutral	0.12
BRCA1	P38398-1.2	A469I	Neutral	0.095
BRCA1	P38398-1.2	A469K	Neutral	0.119
BRCA1	P38398-1.2	A469L	Neutral	0.095
BRCA1	P38398-1.2	A469M	Neutral	0.096
BRCA1	P38398-1.2	A469N	Neutral	0.076
BRCA1	P38398-1.2	A469P	Neutral	0.048
BRCA1	P38398-1.2	A469Q	Neutral	0.079
BRCA1	P38398-1.2	A469R	Neutral	0.152
BRCA1	P38398-1.2	A469S	Neutral	0.016
BRCA1	P38398-1.2	A469T	Neutral	0.036
BRCA1	P38398-1.2	A469V	Neutral	0.046
BRCA1	P38398-1.2	A469W	Neutral	0.339
BRCA1	P38398-1.2	A469Y	Neutral	0.183
BRCA1	P38398-1.2	S470A	Neutral	0.158
BRCA1	P38398-1.2	S470C	Neutral	0.31
BRCA1	P38398-1.2	S470D	Neutral	0.26
BRCA1	P38398-1.2	S470E	Neutral	0.344
BRCA1	P38398-1.2	S470F	Pathogenic	0.654
BRCA1	P38398-1.2	S470G	Neutral	0.294
BRCA1	P38398-1.2	S470H	Neutral	0.482
BRCA1	P38398-1.2	S470I	Pathogenic	0.597
BRCA1	P38398-1.2	S470K	Neutral	0.482
BRCA1	P38398-1.2	S470L	Pathogenic	0.597
BRCA1	P38398-1.2	S470M	Pathogenic	0.51
BRCA1	P38398-1.2	S470N	Neutral	0.215
BRCA1	P38398-1.2	S470P	Neutral	0.331
BRCA1	P38398-1.2	S470Q	Neutral	0.372
BRCA1	P38398-1.2	S470R	Pathogenic	0.641
BRCA1	P38398-1.2	S470T	Neutral	0.205
BRCA1	P38398-1.2	S470V	Neutral	0.496
BRCA1	P38398-1.2	S470W	Pathogenic	0.834
BRCA1	P38398-1.2	S470Y	Pathogenic	0.687
BRCA1	P38398-1.2	L471A	Pathogenic	0.509
BRCA1	P38398-1.2	L471C	Neutral	0.408
BRCA1	P38398-1.2	L471D	Pathogenic	0.64
BRCA1	P38398-1.2	L471E	Neutral	0.453
BRCA1	P38398-1.2	L471F	Neutral	0.21
BRCA1	P38398-1.2	L471G	Pathogenic	0.824
BRCA1	P38398-1.2	L471H	Neutral	0.408
BRCA1	P38398-1.2	L471I	Neutral	0.091
BRCA1	P38398-1.2	L471K	Neutral	0.344
BRCA1	P38398-1.2	L471M	Neutral	0.091
BRCA1	P38398-1.2	L471N	Pathogenic	0.525
BRCA1	P38398-1.2	L471P	Pathogenic	0.565
BRCA1	P38398-1.2	L471Q	Neutral	0.342
BRCA1	P38398-1.2	L471R	Neutral	0.411
BRCA1	P38398-1.2	L471S	Pathogenic	0.564
BRCA1	P38398-1.2	L471T	Neutral	0.367
BRCA1	P38398-1.2	L471V	Neutral	0.18
BRCA1	P38398-1.2	L471W	Pathogenic	0.504
BRCA1	P38398-1.2	L471Y	Neutral	0.301
BRCA1	P38398-1.2	P472A	Pathogenic	0.915
BRCA1	P38398-1.2	P472C	Pathogenic	0.936
BRCA1	P38398-1.2	P472D	Pathogenic	0.866
BRCA1	P38398-1.2	P472E	Pathogenic	0.906
BRCA1	P38398-1.2	P472F	Pathogenic	0.981
BRCA1	P38398-1.2	P472G	Pathogenic	0.959
BRCA1	P38398-1.2	P472H	Pathogenic	0.945
BRCA1	P38398-1.2	P472I	Pathogenic	0.966
BRCA1	P38398-1.2	P472K	Pathogenic	0.945
BRCA1	P38398-1.2	P472L	Pathogenic	0.966
BRCA1	P38398-1.2	P472M	Pathogenic	0.952
BRCA1	P38398-1.2	P472N	Pathogenic	0.912
BRCA1	P38398-1.2	P472Q	Pathogenic	0.916
BRCA1	P38398-1.2	P472R	Pathogenic	0.97
BRCA1	P38398-1.2	P472S	Pathogenic	0.903
BRCA1	P38398-1.2	P472T	Pathogenic	0.873
BRCA1	P38398-1.2	P472V	Pathogenic	0.928
BRCA1	P38398-1.2	P472W	Pathogenic	0.99
BRCA1	P38398-1.2	P472Y	Pathogenic	0.977
BRCA1	P38398-1.2	N473A	Neutral	0.427
BRCA1	P38398-1.2	N473C	Neutral	0.41
BRCA1	P38398-1.2	N473D	Neutral	0.13
BRCA1	P38398-1.2	N473E	Neutral	0.204
BRCA1	P38398-1.2	N473F	Pathogenic	0.566
BRCA1	P38398-1.2	N473G	Neutral	0.356
BRCA1	P38398-1.2	N473H	Neutral	0.177
BRCA1	P38398-1.2	N473I	Pathogenic	0.505
BRCA1	P38398-1.2	N473K	Neutral	0.312
BRCA1	P38398-1.2	N473L	Pathogenic	0.505
BRCA1	P38398-1.2	N473M	Neutral	0.417
BRCA1	P38398-1.2	N473P	Neutral	0.307
BRCA1	P38398-1.2	N473Q	Neutral	0.222
BRCA1	P38398-1.2	N473R	Neutral	0.377
BRCA1	P38398-1.2	N473S	Neutral	0.181
BRCA1	P38398-1.2	N473T	Neutral	0.168
BRCA1	P38398-1.2	N473V	Neutral	0.403
BRCA1	P38398-1.2	N473W	Pathogenic	0.776
BRCA1	P38398-1.2	N473Y	Pathogenic	0.512
BRCA1	P38398-1.2	L474A	Pathogenic	0.507
BRCA1	P38398-1.2	L474C	Neutral	0.406
BRCA1	P38398-1.2	L474D	Pathogenic	0.638
BRCA1	P38398-1.2	L474E	Neutral	0.452
BRCA1	P38398-1.2	L474F	Neutral	0.209
BRCA1	P38398-1.2	L474G	Pathogenic	0.823
BRCA1	P38398-1.2	L474H	Neutral	0.406
BRCA1	P38398-1.2	L474I	Neutral	0.091
BRCA1	P38398-1.2	L474K	Neutral	0.342
BRCA1	P38398-1.2	L474M	Neutral	0.09
BRCA1	P38398-1.2	L474N	Pathogenic	0.524
BRCA1	P38398-1.2	L474P	Pathogenic	0.563
BRCA1	P38398-1.2	L474Q	Neutral	0.34
BRCA1	P38398-1.2	L474R	Neutral	0.41
BRCA1	P38398-1.2	L474S	Pathogenic	0.563
BRCA1	P38398-1.2	L474T	Neutral	0.366
BRCA1	P38398-1.2	L474V	Neutral	0.179
BRCA1	P38398-1.2	L474W	Pathogenic	0.502
BRCA1	P38398-1.2	L474Y	Neutral	0.3
BRCA1	P38398-1.2	S475A	Neutral	0.071
BRCA1	P38398-1.2	S475C	Neutral	0.155
BRCA1	P38398-1.2	S475D	Neutral	0.125
BRCA1	P38398-1.2	S475E	Neutral	0.176
BRCA1	P38398-1.2	S475F	Neutral	0.435
BRCA1	P38398-1.2	S475G	Neutral	0.145
BRCA1	P38398-1.2	S475H	Neutral	0.275
BRCA1	P38398-1.2	S475I	Neutral	0.377
BRCA1	P38398-1.2	S475K	Neutral	0.275
BRCA1	P38398-1.2	S475L	Neutral	0.377
BRCA1	P38398-1.2	S475M	Neutral	0.298
BRCA1	P38398-1.2	S475N	Neutral	0.1
BRCA1	P38398-1.2	S475P	Neutral	0.168
BRCA1	P38398-1.2	S475Q	Neutral	0.194
BRCA1	P38398-1.2	S475R	Neutral	0.421
BRCA1	P38398-1.2	S475T	Neutral	0.095
BRCA1	P38398-1.2	S475V	Neutral	0.286
BRCA1	P38398-1.2	S475W	Pathogenic	0.672
BRCA1	P38398-1.2	S475Y	Neutral	0.472
BRCA1	P38398-1.2	H476A	Pathogenic	0.715
BRCA1	P38398-1.2	H476C	Pathogenic	0.7
BRCA1	P38398-1.2	H476D	Pathogenic	0.502
BRCA1	P38398-1.2	H476E	Neutral	0.32
BRCA1	P38398-1.2	H476F	Neutral	0.443
BRCA1	P38398-1.2	H476G	Pathogenic	0.793
BRCA1	P38398-1.2	H476I	Pathogenic	0.563
BRCA1	P38398-1.2	H476K	Neutral	0.446
BRCA1	P38398-1.2	H476L	Pathogenic	0.564
BRCA1	P38398-1.2	H476M	Neutral	0.476
BRCA1	P38398-1.2	H476N	Neutral	0.304
BRCA1	P38398-1.2	H476P	Pathogenic	0.599
BRCA1	P38398-1.2	H476Q	Neutral	0.298
BRCA1	P38398-1.2	H476R	Neutral	0.427
BRCA1	P38398-1.2	H476S	Pathogenic	0.604
BRCA1	P38398-1.2	H476T	Pathogenic	0.585
BRCA1	P38398-1.2	H476V	Pathogenic	0.604
BRCA1	P38398-1.2	H476W	Pathogenic	0.679
BRCA1	P38398-1.2	H476Y	Neutral	0.237
BRCA1	P38398-1.2	V477A	Neutral	0.047
BRCA1	P38398-1.2	V477C	Neutral	0.045
BRCA1	P38398-1.2	V477D	Neutral	0.078
BRCA1	P38398-1.2	V477E	Neutral	0.045
BRCA1	P38398-1.2	V477F	Neutral	0.057
BRCA1	P38398-1.2	V477G	Neutral	0.183
BRCA1	P38398-1.2	V477H	Neutral	0.078
BRCA1	P38398-1.2	V477I	Neutral	0.011
BRCA1	P38398-1.2	V477K	Neutral	0.077
BRCA1	P38398-1.2	V477L	Neutral	0.022
BRCA1	P38398-1.2	V477M	Neutral	0.022
BRCA1	P38398-1.2	V477N	Neutral	0.071
BRCA1	P38398-1.2	V477P	Neutral	0.059
BRCA1	P38398-1.2	V477Q	Neutral	0.051
BRCA1	P38398-1.2	V477R	Neutral	0.139
BRCA1	P38398-1.2	V477S	Neutral	0.082
BRCA1	P38398-1.2	V477T	Neutral	0.027
BRCA1	P38398-1.2	V477W	Neutral	0.187
BRCA1	P38398-1.2	V477Y	Neutral	0.065
BRCA1	P38398-1.2	T478A	Neutral	0.073
BRCA1	P38398-1.2	T478C	Neutral	0.068
BRCA1	P38398-1.2	T478D	Neutral	0.061
BRCA1	P38398-1.2	T478E	Neutral	0.082
BRCA1	P38398-1.2	T478F	Neutral	0.184
BRCA1	P38398-1.2	T478G	Neutral	0.199
BRCA1	P38398-1.2	T478H	Neutral	0.137
BRCA1	P38398-1.2	T478I	Neutral	0.11
BRCA1	P38398-1.2	T478K	Neutral	0.136
BRCA1	P38398-1.2	T478L	Neutral	0.11
BRCA1	P38398-1.2	T478M	Neutral	0.111
BRCA1	P38398-1.2	T478N	Neutral	0.044
BRCA1	P38398-1.2	T478P	Neutral	0.063
BRCA1	P38398-1.2	T478Q	Neutral	0.091
BRCA1	P38398-1.2	T478R	Neutral	0.174
BRCA1	P38398-1.2	T478S	Neutral	0.046
BRCA1	P38398-1.2	T478V	Neutral	0.054
BRCA1	P38398-1.2	T478W	Neutral	0.295
BRCA1	P38398-1.2	T478Y	Neutral	0.208
BRCA1	P38398-1.2	E479A	Pathogenic	0.824
BRCA1	P38398-1.2	E479C	Pathogenic	0.901
BRCA1	P38398-1.2	E479D	Neutral	0.484
BRCA1	P38398-1.2	E479F	Pathogenic	0.869
BRCA1	P38398-1.2	E479G	Pathogenic	0.912
BRCA1	P38398-1.2	E479H	Pathogenic	0.611
BRCA1	P38398-1.2	E479I	Pathogenic	0.838
BRCA1	P38398-1.2	E479K	Pathogenic	0.617
BRCA1	P38398-1.2	E479L	Pathogenic	0.839
BRCA1	P38398-1.2	E479M	Pathogenic	0.785
BRCA1	P38398-1.2	E479N	Pathogenic	0.636
BRCA1	P38398-1.2	E479P	Pathogenic	0.737
BRCA1	P38398-1.2	E479Q	Neutral	0.412
BRCA1	P38398-1.2	E479R	Pathogenic	0.755
BRCA1	P38398-1.2	E479S	Pathogenic	0.742
BRCA1	P38398-1.2	E479T	Pathogenic	0.725
BRCA1	P38398-1.2	E479V	Pathogenic	0.741
BRCA1	P38398-1.2	E479W	Pathogenic	0.924
BRCA1	P38398-1.2	E479Y	Pathogenic	0.842
BRCA1	P38398-1.2	N480A	Neutral	0.154
BRCA1	P38398-1.2	N480C	Neutral	0.145
BRCA1	P38398-1.2	N480D	Neutral	0.035
BRCA1	P38398-1.2	N480E	Neutral	0.059
BRCA1	P38398-1.2	N480F	Neutral	0.241
BRCA1	P38398-1.2	N480G	Neutral	0.119
BRCA1	P38398-1.2	N480H	Neutral	0.05
BRCA1	P38398-1.2	N480I	Neutral	0.199
BRCA1	P38398-1.2	N480K	Neutral	0.1
BRCA1	P38398-1.2	N480L	Neutral	0.199
BRCA1	P38398-1.2	N480M	Neutral	0.149
BRCA1	P38398-1.2	N480P	Neutral	0.098
BRCA1	P38398-1.2	N480Q	Neutral	0.065
BRCA1	P38398-1.2	N480R	Neutral	0.129
BRCA1	P38398-1.2	N480S	Neutral	0.051
BRCA1	P38398-1.2	N480T	Neutral	0.047
BRCA1	P38398-1.2	N480V	Neutral	0.141
BRCA1	P38398-1.2	N480W	Neutral	0.457
BRCA1	P38398-1.2	N480Y	Neutral	0.204
BRCA1	P38398-1.2	L481A	Pathogenic	0.543
BRCA1	P38398-1.2	L481C	Neutral	0.441
BRCA1	P38398-1.2	L481D	Pathogenic	0.671
BRCA1	P38398-1.2	L481E	Neutral	0.487
BRCA1	P38398-1.2	L481F	Neutral	0.234
BRCA1	P38398-1.2	L481G	Pathogenic	0.843
BRCA1	P38398-1.2	L481H	Neutral	0.441
BRCA1	P38398-1.2	L481I	Neutral	0.103
BRCA1	P38398-1.2	L481K	Neutral	0.375
BRCA1	P38398-1.2	L481M	Neutral	0.103
BRCA1	P38398-1.2	L481N	Pathogenic	0.56
BRCA1	P38398-1.2	L481P	Pathogenic	0.598
BRCA1	P38398-1.2	L481Q	Neutral	0.373
BRCA1	P38398-1.2	L481R	Neutral	0.445
BRCA1	P38398-1.2	L481S	Pathogenic	0.598
BRCA1	P38398-1.2	L481T	Neutral	0.4
BRCA1	P38398-1.2	L481V	Neutral	0.201
BRCA1	P38398-1.2	L481W	Pathogenic	0.538
BRCA1	P38398-1.2	L481Y	Neutral	0.331
BRCA1	P38398-1.2	I482A	Neutral	0.429
BRCA1	P38398-1.2	I482C	Neutral	0.333
BRCA1	P38398-1.2	I482D	Neutral	0.472
BRCA1	P38398-1.2	I482E	Neutral	0.375
BRCA1	P38398-1.2	I482F	Neutral	0.162
BRCA1	P38398-1.2	I482G	Pathogenic	0.772
BRCA1	P38398-1.2	I482H	Neutral	0.333
BRCA1	P38398-1.2	I482K	Neutral	0.353
BRCA1	P38398-1.2	I482L	Neutral	0.068
BRCA1	P38398-1.2	I482M	Neutral	0.094
BRCA1	P38398-1.2	I482N	Neutral	0.445
BRCA1	P38398-1.2	I482P	Neutral	0.485
BRCA1	P38398-1.2	I482Q	Neutral	0.351
BRCA1	P38398-1.2	I482R	Neutral	0.421
BRCA1	P38398-1.2	I482S	Neutral	0.484
BRCA1	P38398-1.2	I482T	Neutral	0.296
BRCA1	P38398-1.2	I482V	Neutral	0.071
BRCA1	P38398-1.2	I482W	Pathogenic	0.515
BRCA1	P38398-1.2	I482Y	Neutral	0.238
BRCA1	P38398-1.2	I483A	Neutral	0.058
BRCA1	P38398-1.2	I483C	Neutral	0.039
BRCA1	P38398-1.2	I483D	Neutral	0.068
BRCA1	P38398-1.2	I483E	Neutral	0.047
BRCA1	P38398-1.2	I483F	Neutral	0.015
BRCA1	P38398-1.2	I483G	Neutral	0.216
BRCA1	P38398-1.2	I483H	Neutral	0.039
BRCA1	P38398-1.2	I483K	Neutral	0.043
BRCA1	P38398-1.2	I483L	Neutral	0.006
BRCA1	P38398-1.2	I483M	Neutral	0.008
BRCA1	P38398-1.2	I483N	Neutral	0.061
BRCA1	P38398-1.2	I483P	Neutral	0.071
BRCA1	P38398-1.2	I483Q	Neutral	0.042
BRCA1	P38398-1.2	I483R	Neutral	0.056
BRCA1	P38398-1.2	I483S	Neutral	0.071
BRCA1	P38398-1.2	I483T	Neutral	0.033
BRCA1	P38398-1.2	I483V	Neutral	0.006
BRCA1	P38398-1.2	I483W	Neutral	0.08
BRCA1	P38398-1.2	I483Y	Neutral	0.025
BRCA1	P38398-1.2	G484A	Neutral	0.353
BRCA1	P38398-1.2	G484C	Pathogenic	0.71
BRCA1	P38398-1.2	G484D	Pathogenic	0.57
BRCA1	P38398-1.2	G484E	Pathogenic	0.74
BRCA1	P38398-1.2	G484F	Pathogenic	0.877
BRCA1	P38398-1.2	G484H	Pathogenic	0.778
BRCA1	P38398-1.2	G484I	Pathogenic	0.89
BRCA1	P38398-1.2	G484K	Pathogenic	0.834
BRCA1	P38398-1.2	G484L	Pathogenic	0.89
BRCA1	P38398-1.2	G484M	Pathogenic	0.85
BRCA1	P38398-1.2	G484N	Pathogenic	0.508
BRCA1	P38398-1.2	G484P	Pathogenic	0.651
BRCA1	P38398-1.2	G484Q	Pathogenic	0.762
BRCA1	P38398-1.2	G484R	Pathogenic	0.871
BRCA1	P38398-1.2	G484S	Neutral	0.385
BRCA1	P38398-1.2	G484T	Pathogenic	0.668
BRCA1	P38398-1.2	G484V	Pathogenic	0.788
BRCA1	P38398-1.2	G484W	Pathogenic	0.902
BRCA1	P38398-1.2	G484Y	Pathogenic	0.892
BRCA1	P38398-1.2	A485C	Pathogenic	0.537
BRCA1	P38398-1.2	A485D	Pathogenic	0.727
BRCA1	P38398-1.2	A485E	Pathogenic	0.734
BRCA1	P38398-1.2	A485F	Pathogenic	0.875
BRCA1	P38398-1.2	A485G	Pathogenic	0.539
BRCA1	P38398-1.2	A485H	Pathogenic	0.831
BRCA1	P38398-1.2	A485I	Pathogenic	0.792
BRCA1	P38398-1.2	A485K	Pathogenic	0.83
BRCA1	P38398-1.2	A485L	Pathogenic	0.793
BRCA1	P38398-1.2	A485M	Pathogenic	0.794
BRCA1	P38398-1.2	A485N	Pathogenic	0.749
BRCA1	P38398-1.2	A485P	Pathogenic	0.647
BRCA1	P38398-1.2	A485Q	Pathogenic	0.757
BRCA1	P38398-1.2	A485R	Pathogenic	0.867
BRCA1	P38398-1.2	A485S	Neutral	0.378
BRCA1	P38398-1.2	A485T	Pathogenic	0.578
BRCA1	P38398-1.2	A485V	Pathogenic	0.638
BRCA1	P38398-1.2	A485W	Pathogenic	0.949
BRCA1	P38398-1.2	A485Y	Pathogenic	0.891
BRCA1	P38398-1.2	F486A	Neutral	0.013
BRCA1	P38398-1.2	F486C	Neutral	0.009
BRCA1	P38398-1.2	F486D	Neutral	0.011
BRCA1	P38398-1.2	F486E	Neutral	0.007
BRCA1	P38398-1.2	F486G	Neutral	0.028
BRCA1	P38398-1.2	F486H	Neutral	0.003
BRCA1	P38398-1.2	F486I	Neutral	0.002
BRCA1	P38398-1.2	F486K	Neutral	0.004
BRCA1	P38398-1.2	F486L	Neutral	0.002
BRCA1	P38398-1.2	F486M	Neutral	0.002
BRCA1	P38398-1.2	F486N	Neutral	0.01
BRCA1	P38398-1.2	F486P	Neutral	0.016
BRCA1	P38398-1.2	F486Q	Neutral	0.007
BRCA1	P38398-1.2	F486R	Neutral	0.005
BRCA1	P38398-1.2	F486S	Neutral	0.011
BRCA1	P38398-1.2	F486T	Neutral	0.007
BRCA1	P38398-1.2	F486V	Neutral	0.004
BRCA1	P38398-1.2	F486W	Neutral	0.002
BRCA1	P38398-1.2	F486Y	Neutral	0.001
BRCA1	P38398-1.2	V487A	Neutral	0.031
BRCA1	P38398-1.2	V487C	Neutral	0.03
BRCA1	P38398-1.2	V487D	Neutral	0.052
BRCA1	P38398-1.2	V487E	Neutral	0.03
BRCA1	P38398-1.2	V487F	Neutral	0.038
BRCA1	P38398-1.2	V487G	Neutral	0.127
BRCA1	P38398-1.2	V487H	Neutral	0.052
BRCA1	P38398-1.2	V487I	Neutral	0.007
BRCA1	P38398-1.2	V487K	Neutral	0.052
BRCA1	P38398-1.2	V487L	Neutral	0.015
BRCA1	P38398-1.2	V487M	Neutral	0.015
BRCA1	P38398-1.2	V487N	Neutral	0.047
BRCA1	P38398-1.2	V487P	Neutral	0.039
BRCA1	P38398-1.2	V487Q	Neutral	0.034
BRCA1	P38398-1.2	V487R	Neutral	0.095
BRCA1	P38398-1.2	V487S	Neutral	0.055
BRCA1	P38398-1.2	V487T	Neutral	0.018
BRCA1	P38398-1.2	V487W	Neutral	0.13
BRCA1	P38398-1.2	V487Y	Neutral	0.043
BRCA1	P38398-1.2	T488A	Neutral	0.002
BRCA1	P38398-1.2	T488C	Neutral	0.002
BRCA1	P38398-1.2	T488D	Neutral	0.002
BRCA1	P38398-1.2	T488E	Neutral	0.003
BRCA1	P38398-1.2	T488F	Neutral	0.007
BRCA1	P38398-1.2	T488G	Neutral	0.007
BRCA1	P38398-1.2	T488H	Neutral	0.005
BRCA1	P38398-1.2	T488I	Neutral	0.004
BRCA1	P38398-1.2	T488K	Neutral	0.005
BRCA1	P38398-1.2	T488L	Neutral	0.004
BRCA1	P38398-1.2	T488M	Neutral	0.004
BRCA1	P38398-1.2	T488N	Neutral	0.001
BRCA1	P38398-1.2	T488P	Neutral	0.002
BRCA1	P38398-1.2	T488Q	Neutral	0.003
BRCA1	P38398-1.2	T488R	Neutral	0.006
BRCA1	P38398-1.2	T488S	Neutral	0.001
BRCA1	P38398-1.2	T488V	Neutral	0.002
BRCA1	P38398-1.2	T488W	Neutral	0.013
BRCA1	P38398-1.2	T488Y	Neutral	0.008
BRCA1	P38398-1.2	E489A	Neutral	0.464
BRCA1	P38398-1.2	E489C	Pathogenic	0.625
BRCA1	P38398-1.2	E489D	Neutral	0.147
BRCA1	P38398-1.2	E489F	Pathogenic	0.55
BRCA1	P38398-1.2	E489G	Pathogenic	0.656
BRCA1	P38398-1.2	E489H	Neutral	0.225
BRCA1	P38398-1.2	E489I	Neutral	0.489
BRCA1	P38398-1.2	E489K	Neutral	0.228
BRCA1	P38398-1.2	E489L	Neutral	0.489
BRCA1	P38398-1.2	E489M	Neutral	0.402
BRCA1	P38398-1.2	E489N	Neutral	0.243
BRCA1	P38398-1.2	E489P	Neutral	0.34
BRCA1	P38398-1.2	E489Q	Neutral	0.114
BRCA1	P38398-1.2	E489R	Neutral	0.362
BRCA1	P38398-1.2	E489S	Neutral	0.346
BRCA1	P38398-1.2	E489T	Neutral	0.327
BRCA1	P38398-1.2	E489V	Neutral	0.345
BRCA1	P38398-1.2	E489W	Pathogenic	0.693
BRCA1	P38398-1.2	E489Y	Neutral	0.496
BRCA1	P38398-1.2	P490A	Pathogenic	0.779
BRCA1	P38398-1.2	P490C	Pathogenic	0.827
BRCA1	P38398-1.2	P490D	Pathogenic	0.679
BRCA1	P38398-1.2	P490E	Pathogenic	0.76
BRCA1	P38398-1.2	P490F	Pathogenic	0.944
BRCA1	P38398-1.2	P490G	Pathogenic	0.885
BRCA1	P38398-1.2	P490H	Pathogenic	0.85
BRCA1	P38398-1.2	P490I	Pathogenic	0.902
BRCA1	P38398-1.2	P490K	Pathogenic	0.848
BRCA1	P38398-1.2	P490L	Pathogenic	0.902
BRCA1	P38398-1.2	P490M	Pathogenic	0.866
BRCA1	P38398-1.2	P490N	Pathogenic	0.773
BRCA1	P38398-1.2	P490Q	Pathogenic	0.781
BRCA1	P38398-1.2	P490R	Pathogenic	0.915
BRCA1	P38398-1.2	P490S	Pathogenic	0.754
BRCA1	P38398-1.2	P490T	Pathogenic	0.693
BRCA1	P38398-1.2	P490V	Pathogenic	0.809
BRCA1	P38398-1.2	P490W	Pathogenic	0.969
BRCA1	P38398-1.2	P490Y	Pathogenic	0.932
BRCA1	P38398-1.2	Q491A	Neutral	0.47
BRCA1	P38398-1.2	Q491C	Pathogenic	0.543
BRCA1	P38398-1.2	Q491D	Neutral	0.266
BRCA1	P38398-1.2	Q491E	Neutral	0.105
BRCA1	P38398-1.2	Q491F	Pathogenic	0.501
BRCA1	P38398-1.2	Q491G	Pathogenic	0.662
BRCA1	P38398-1.2	Q491H	Neutral	0.192
BRCA1	P38398-1.2	Q491I	Neutral	0.44
BRCA1	P38398-1.2	Q491K	Neutral	0.193
BRCA1	P38398-1.2	Q491L	Neutral	0.353
BRCA1	P38398-1.2	Q491M	Neutral	0.21
BRCA1	P38398-1.2	Q491N	Neutral	0.245
BRCA1	P38398-1.2	Q491P	Neutral	0.346
BRCA1	P38398-1.2	Q491R	Neutral	0.242
BRCA1	P38398-1.2	Q491S	Neutral	0.352
BRCA1	P38398-1.2	Q491T	Neutral	0.333
BRCA1	P38398-1.2	Q491V	Neutral	0.35
BRCA1	P38398-1.2	Q491W	Pathogenic	0.562
BRCA1	P38398-1.2	Q491Y	Neutral	0.36
BRCA1	P38398-1.2	I492A	Neutral	0.455
BRCA1	P38398-1.2	I492C	Neutral	0.357
BRCA1	P38398-1.2	I492D	Neutral	0.499
BRCA1	P38398-1.2	I492E	Neutral	0.401
BRCA1	P38398-1.2	I492F	Neutral	0.177
BRCA1	P38398-1.2	I492G	Pathogenic	0.791
BRCA1	P38398-1.2	I492H	Neutral	0.357
BRCA1	P38398-1.2	I492K	Neutral	0.378
BRCA1	P38398-1.2	I492L	Neutral	0.075
BRCA1	P38398-1.2	I492M	Neutral	0.104
BRCA1	P38398-1.2	I492N	Neutral	0.472
BRCA1	P38398-1.2	I492P	Pathogenic	0.512
BRCA1	P38398-1.2	I492Q	Neutral	0.376
BRCA1	P38398-1.2	I492R	Neutral	0.448
BRCA1	P38398-1.2	I492S	Pathogenic	0.511
BRCA1	P38398-1.2	I492T	Neutral	0.319
BRCA1	P38398-1.2	I492V	Neutral	0.079
BRCA1	P38398-1.2	I492W	Pathogenic	0.542
BRCA1	P38398-1.2	I492Y	Neutral	0.258
BRCA1	P38398-1.2	I493A	Neutral	0.075
BRCA1	P38398-1.2	I493C	Neutral	0.051
BRCA1	P38398-1.2	I493D	Neutral	0.088
BRCA1	P38398-1.2	I493E	Neutral	0.061
BRCA1	P38398-1.2	I493F	Neutral	0.02
BRCA1	P38398-1.2	I493G	Neutral	0.267
BRCA1	P38398-1.2	I493H	Neutral	0.051
BRCA1	P38398-1.2	I493K	Neutral	0.055
BRCA1	P38398-1.2	I493L	Neutral	0.008
BRCA1	P38398-1.2	I493M	Neutral	0.011
BRCA1	P38398-1.2	I493N	Neutral	0.079
BRCA1	P38398-1.2	I493P	Neutral	0.092
BRCA1	P38398-1.2	I493Q	Neutral	0.055
BRCA1	P38398-1.2	I493R	Neutral	0.073
BRCA1	P38398-1.2	I493S	Neutral	0.092
BRCA1	P38398-1.2	I493T	Neutral	0.043
BRCA1	P38398-1.2	I493V	Neutral	0.008
BRCA1	P38398-1.2	I493W	Neutral	0.103
BRCA1	P38398-1.2	I493Y	Neutral	0.032
BRCA1	P38398-1.2	Q494A	Pathogenic	0.648
BRCA1	P38398-1.2	Q494C	Pathogenic	0.711
BRCA1	P38398-1.2	Q494D	Neutral	0.428
BRCA1	P38398-1.2	Q494E	Neutral	0.196
BRCA1	P38398-1.2	Q494F	Pathogenic	0.675
BRCA1	P38398-1.2	Q494G	Pathogenic	0.802
BRCA1	P38398-1.2	Q494H	Neutral	0.33
BRCA1	P38398-1.2	Q494I	Pathogenic	0.619
BRCA1	P38398-1.2	Q494K	Neutral	0.332
BRCA1	P38398-1.2	Q494L	Pathogenic	0.531
BRCA1	P38398-1.2	Q494M	Neutral	0.356
BRCA1	P38398-1.2	Q494N	Neutral	0.402
BRCA1	P38398-1.2	Q494P	Pathogenic	0.523
BRCA1	P38398-1.2	Q494R	Neutral	0.398
BRCA1	P38398-1.2	Q494S	Pathogenic	0.53
BRCA1	P38398-1.2	Q494T	Pathogenic	0.508
BRCA1	P38398-1.2	Q494V	Pathogenic	0.528
BRCA1	P38398-1.2	Q494W	Pathogenic	0.727
BRCA1	P38398-1.2	Q494Y	Pathogenic	0.538
BRCA1	P38398-1.2	E495A	Neutral	0.346
BRCA1	P38398-1.2	E495C	Pathogenic	0.505
BRCA1	P38398-1.2	E495D	Neutral	0.096
BRCA1	P38398-1.2	E495F	Neutral	0.428
BRCA1	P38398-1.2	E495G	Pathogenic	0.539
BRCA1	P38398-1.2	E495H	Neutral	0.151
BRCA1	P38398-1.2	E495I	Neutral	0.369
BRCA1	P38398-1.2	E495K	Neutral	0.154
BRCA1	P38398-1.2	E495L	Neutral	0.37
BRCA1	P38398-1.2	E495M	Neutral	0.291
BRCA1	P38398-1.2	E495N	Neutral	0.164
BRCA1	P38398-1.2	E495P	Neutral	0.24
BRCA1	P38398-1.2	E495Q	Neutral	0.073
BRCA1	P38398-1.2	E495R	Neutral	0.258
BRCA1	P38398-1.2	E495S	Neutral	0.245
BRCA1	P38398-1.2	E495T	Neutral	0.229
BRCA1	P38398-1.2	E495V	Neutral	0.244
BRCA1	P38398-1.2	E495W	Pathogenic	0.58
BRCA1	P38398-1.2	E495Y	Neutral	0.376
BRCA1	P38398-1.2	R496A	Neutral	0.019
BRCA1	P38398-1.2	R496C	Neutral	0.026
BRCA1	P38398-1.2	R496D	Neutral	0.017
BRCA1	P38398-1.2	R496E	Neutral	0.005
BRCA1	P38398-1.2	R496F	Neutral	0.009
BRCA1	P38398-1.2	R496G	Neutral	0.041
BRCA1	P38398-1.2	R496H	Neutral	0.004
BRCA1	P38398-1.2	R496I	Neutral	0.011
BRCA1	P38398-1.2	R496K	Neutral	0.001
BRCA1	P38398-1.2	R496L	Neutral	0.008
BRCA1	P38398-1.2	R496M	Neutral	0.005
BRCA1	P38398-1.2	R496N	Neutral	0.007
BRCA1	P38398-1.2	R496P	Neutral	0.017
BRCA1	P38398-1.2	R496Q	Neutral	0.003
BRCA1	P38398-1.2	R496S	Neutral	0.017
BRCA1	P38398-1.2	R496T	Neutral	0.011
BRCA1	P38398-1.2	R496V	Neutral	0.017
BRCA1	P38398-1.2	R496W	Neutral	0.009
BRCA1	P38398-1.2	R496Y	Neutral	0.005
BRCA1	P38398-1.2	P497A	Pathogenic	0.862
BRCA1	P38398-1.2	P497C	Pathogenic	0.895
BRCA1	P38398-1.2	P497D	Pathogenic	0.79
BRCA1	P38398-1.2	P497E	Pathogenic	0.849
BRCA1	P38398-1.2	P497F	Pathogenic	0.968
BRCA1	P38398-1.2	P497G	Pathogenic	0.932
BRCA1	P38398-1.2	P497H	Pathogenic	0.909
BRCA1	P38398-1.2	P497I	Pathogenic	0.942
BRCA1	P38398-1.2	P497K	Pathogenic	0.909
BRCA1	P38398-1.2	P497L	Pathogenic	0.942
BRCA1	P38398-1.2	P497M	Pathogenic	0.92
BRCA1	P38398-1.2	P497N	Pathogenic	0.858
BRCA1	P38398-1.2	P497Q	Pathogenic	0.864
BRCA1	P38398-1.2	P497R	Pathogenic	0.95
BRCA1	P38398-1.2	P497S	Pathogenic	0.845
BRCA1	P38398-1.2	P497T	Pathogenic	0.8
BRCA1	P38398-1.2	P497V	Pathogenic	0.883
BRCA1	P38398-1.2	P497W	Pathogenic	0.982
BRCA1	P38398-1.2	P497Y	Pathogenic	0.96
BRCA1	P38398-1.2	L498A	Neutral	0.251
BRCA1	P38398-1.2	L498C	Neutral	0.182
BRCA1	P38398-1.2	L498D	Neutral	0.365
BRCA1	P38398-1.2	L498E	Neutral	0.211
BRCA1	P38398-1.2	L498F	Neutral	0.079
BRCA1	P38398-1.2	L498G	Pathogenic	0.602
BRCA1	P38398-1.2	L498H	Neutral	0.182
BRCA1	P38398-1.2	L498I	Neutral	0.031
BRCA1	P38398-1.2	L498K	Neutral	0.145
BRCA1	P38398-1.2	L498M	Neutral	0.031
BRCA1	P38398-1.2	L498N	Neutral	0.264
BRCA1	P38398-1.2	L498P	Neutral	0.296
BRCA1	P38398-1.2	L498Q	Neutral	0.144
BRCA1	P38398-1.2	L498R	Neutral	0.184
BRCA1	P38398-1.2	L498S	Neutral	0.295
BRCA1	P38398-1.2	L498T	Neutral	0.158
BRCA1	P38398-1.2	L498V	Neutral	0.066
BRCA1	P38398-1.2	L498W	Neutral	0.247
BRCA1	P38398-1.2	L498Y	Neutral	0.122
BRCA1	P38398-1.2	T499A	Pathogenic	0.61
BRCA1	P38398-1.2	T499C	Pathogenic	0.593
BRCA1	P38398-1.2	T499D	Pathogenic	0.565
BRCA1	P38398-1.2	T499E	Pathogenic	0.64
BRCA1	P38398-1.2	T499F	Pathogenic	0.818
BRCA1	P38398-1.2	T499G	Pathogenic	0.831
BRCA1	P38398-1.2	T499H	Pathogenic	0.76
BRCA1	P38398-1.2	T499I	Pathogenic	0.71
BRCA1	P38398-1.2	T499K	Pathogenic	0.758
BRCA1	P38398-1.2	T499L	Pathogenic	0.71
BRCA1	P38398-1.2	T499M	Pathogenic	0.712
BRCA1	P38398-1.2	T499N	Neutral	0.48
BRCA1	P38398-1.2	T499P	Pathogenic	0.573
BRCA1	P38398-1.2	T499Q	Pathogenic	0.667
BRCA1	P38398-1.2	T499R	Pathogenic	0.807
BRCA1	P38398-1.2	T499S	Neutral	0.486
BRCA1	P38398-1.2	T499V	Pathogenic	0.53
BRCA1	P38398-1.2	T499W	Pathogenic	0.892
BRCA1	P38398-1.2	T499Y	Pathogenic	0.839
BRCA1	P38398-1.2	N500A	Pathogenic	0.735
BRCA1	P38398-1.2	N500C	Pathogenic	0.721
BRCA1	P38398-1.2	N500D	Neutral	0.357
BRCA1	P38398-1.2	N500E	Neutral	0.488
BRCA1	P38398-1.2	N500F	Pathogenic	0.829
BRCA1	P38398-1.2	N500G	Pathogenic	0.673
BRCA1	P38398-1.2	N500H	Neutral	0.444
BRCA1	P38398-1.2	N500I	Pathogenic	0.791
BRCA1	P38398-1.2	N500K	Pathogenic	0.628
BRCA1	P38398-1.2	N500L	Pathogenic	0.792
BRCA1	P38398-1.2	N500M	Pathogenic	0.727
BRCA1	P38398-1.2	N500P	Pathogenic	0.623
BRCA1	P38398-1.2	N500Q	Pathogenic	0.515
BRCA1	P38398-1.2	N500R	Pathogenic	0.693
BRCA1	P38398-1.2	N500S	Neutral	0.451
BRCA1	P38398-1.2	N500T	Neutral	0.429
BRCA1	P38398-1.2	N500V	Pathogenic	0.716
BRCA1	P38398-1.2	N500W	Pathogenic	0.928
BRCA1	P38398-1.2	N500Y	Pathogenic	0.796
BRCA1	P38398-1.2	K501A	Pathogenic	0.738
BRCA1	P38398-1.2	K501C	Pathogenic	0.79
BRCA1	P38398-1.2	K501D	Pathogenic	0.627
BRCA1	P38398-1.2	K501E	Neutral	0.352
BRCA1	P38398-1.2	K501F	Pathogenic	0.555
BRCA1	P38398-1.2	K501G	Pathogenic	0.861
BRCA1	P38398-1.2	K501H	Neutral	0.476
BRCA1	P38398-1.2	K501I	Pathogenic	0.615
BRCA1	P38398-1.2	K501L	Pathogenic	0.526
BRCA1	P38398-1.2	K501M	Neutral	0.438
BRCA1	P38398-1.2	K501N	Pathogenic	0.511
BRCA1	P38398-1.2	K501P	Pathogenic	0.626
BRCA1	P38398-1.2	K501Q	Neutral	0.326
BRCA1	P38398-1.2	K501R	Neutral	0.222
BRCA1	P38398-1.2	K501S	Pathogenic	0.633
BRCA1	P38398-1.2	K501T	Pathogenic	0.612
BRCA1	P38398-1.2	K501V	Pathogenic	0.631
BRCA1	P38398-1.2	K501W	Pathogenic	0.698
BRCA1	P38398-1.2	K501Y	Pathogenic	0.502
BRCA1	P38398-1.2	L502A	Pathogenic	0.736
BRCA1	P38398-1.2	L502C	Pathogenic	0.649
BRCA1	P38398-1.2	L502D	Pathogenic	0.827
BRCA1	P38398-1.2	L502E	Pathogenic	0.69
BRCA1	P38398-1.2	L502F	Neutral	0.417
BRCA1	P38398-1.2	L502G	Pathogenic	0.926
BRCA1	P38398-1.2	L502H	Pathogenic	0.65
BRCA1	P38398-1.2	L502I	Neutral	0.213
BRCA1	P38398-1.2	L502K	Pathogenic	0.585
BRCA1	P38398-1.2	L502M	Neutral	0.212
BRCA1	P38398-1.2	L502N	Pathogenic	0.749
BRCA1	P38398-1.2	L502P	Pathogenic	0.777
BRCA1	P38398-1.2	L502Q	Pathogenic	0.583
BRCA1	P38398-1.2	L502R	Pathogenic	0.653
BRCA1	P38398-1.2	L502S	Pathogenic	0.777
BRCA1	P38398-1.2	L502T	Pathogenic	0.61
BRCA1	P38398-1.2	L502V	Neutral	0.371
BRCA1	P38398-1.2	L502W	Pathogenic	0.732
BRCA1	P38398-1.2	L502Y	Pathogenic	0.537
BRCA1	P38398-1.2	K503A	Pathogenic	0.98
BRCA1	P38398-1.2	K503C	Pathogenic	0.985
BRCA1	P38398-1.2	K503D	Pathogenic	0.966
BRCA1	P38398-1.2	K503E	Pathogenic	0.903
BRCA1	P38398-1.2	K503F	Pathogenic	0.955
BRCA1	P38398-1.2	K503G	Pathogenic	0.991
BRCA1	P38398-1.2	K503H	Pathogenic	0.94
BRCA1	P38398-1.2	K503I	Pathogenic	0.965
BRCA1	P38398-1.2	K503L	Pathogenic	0.95
BRCA1	P38398-1.2	K503M	Pathogenic	0.93
BRCA1	P38398-1.2	K503N	Pathogenic	0.947
BRCA1	P38398-1.2	K503P	Pathogenic	0.966
BRCA1	P38398-1.2	K503Q	Pathogenic	0.892
BRCA1	P38398-1.2	K503R	Pathogenic	0.83
BRCA1	P38398-1.2	K503S	Pathogenic	0.967
BRCA1	P38398-1.2	K503T	Pathogenic	0.964
BRCA1	P38398-1.2	K503V	Pathogenic	0.967
BRCA1	P38398-1.2	K503W	Pathogenic	0.975
BRCA1	P38398-1.2	K503Y	Pathogenic	0.945
BRCA1	P38398-1.2	R504A	Pathogenic	0.895
BRCA1	P38398-1.2	R504C	Pathogenic	0.92
BRCA1	P38398-1.2	R504D	Pathogenic	0.88
BRCA1	P38398-1.2	R504E	Pathogenic	0.704
BRCA1	P38398-1.2	R504F	Pathogenic	0.791
BRCA1	P38398-1.2	R504G	Pathogenic	0.95
BRCA1	P38398-1.2	R504H	Pathogenic	0.657
BRCA1	P38398-1.2	R504I	Pathogenic	0.829
BRCA1	P38398-1.2	R504K	Neutral	0.393
BRCA1	P38398-1.2	R504L	Pathogenic	0.771
BRCA1	P38398-1.2	R504M	Pathogenic	0.703
BRCA1	P38398-1.2	R504N	Pathogenic	0.76
BRCA1	P38398-1.2	R504P	Pathogenic	0.88
BRCA1	P38398-1.2	R504Q	Pathogenic	0.594
BRCA1	P38398-1.2	R504S	Pathogenic	0.883
BRCA1	P38398-1.2	R504T	Pathogenic	0.827
BRCA1	P38398-1.2	R504V	Pathogenic	0.882
BRCA1	P38398-1.2	R504W	Pathogenic	0.797
BRCA1	P38398-1.2	R504Y	Pathogenic	0.701
BRCA1	P38398-1.2	K505A	Pathogenic	0.984
BRCA1	P38398-1.2	K505C	Pathogenic	0.988
BRCA1	P38398-1.2	K505D	Pathogenic	0.973
BRCA1	P38398-1.2	K505E	Pathogenic	0.921
BRCA1	P38398-1.2	K505F	Pathogenic	0.964
BRCA1	P38398-1.2	K505G	Pathogenic	0.993
BRCA1	P38398-1.2	K505H	Pathogenic	0.951
BRCA1	P38398-1.2	K505I	Pathogenic	0.971
BRCA1	P38398-1.2	K505L	Pathogenic	0.96
BRCA1	P38398-1.2	K505M	Pathogenic	0.943
BRCA1	P38398-1.2	K505N	Pathogenic	0.957
BRCA1	P38398-1.2	K505P	Pathogenic	0.973
BRCA1	P38398-1.2	K505Q	Pathogenic	0.912
BRCA1	P38398-1.2	K505R	Pathogenic	0.859
BRCA1	P38398-1.2	K505S	Pathogenic	0.974
BRCA1	P38398-1.2	K505T	Pathogenic	0.971
BRCA1	P38398-1.2	K505V	Pathogenic	0.973
BRCA1	P38398-1.2	K505W	Pathogenic	0.98
BRCA1	P38398-1.2	K505Y	Pathogenic	0.956
BRCA1	P38398-1.2	R506A	Pathogenic	0.995
BRCA1	P38398-1.2	R506C	Pathogenic	0.996
BRCA1	P38398-1.2	R506D	Pathogenic	0.995
BRCA1	P38398-1.2	R506E	Pathogenic	0.983
BRCA1	P38398-1.2	R506F	Pathogenic	0.99
BRCA1	P38398-1.2	R506G	Pathogenic	0.998
BRCA1	P38398-1.2	R506H	Pathogenic	0.979
BRCA1	P38398-1.2	R506I	Pathogenic	0.992
BRCA1	P38398-1.2	R506K	Pathogenic	0.942
BRCA1	P38398-1.2	R506L	Pathogenic	0.988
BRCA1	P38398-1.2	R506M	Pathogenic	0.983
BRCA1	P38398-1.2	R506N	Pathogenic	0.987
BRCA1	P38398-1.2	R506P	Pathogenic	0.995
BRCA1	P38398-1.2	R506Q	Pathogenic	0.973
BRCA1	P38398-1.2	R506S	Pathogenic	0.995
BRCA1	P38398-1.2	R506T	Pathogenic	0.992
BRCA1	P38398-1.2	R506V	Pathogenic	0.995
BRCA1	P38398-1.2	R506W	Pathogenic	0.99
BRCA1	P38398-1.2	R506Y	Pathogenic	0.983
BRCA1	P38398-1.2	R507A	Pathogenic	0.976
BRCA1	P38398-1.2	R507C	Pathogenic	0.982
BRCA1	P38398-1.2	R507D	Pathogenic	0.973
BRCA1	P38398-1.2	R507E	Pathogenic	0.92
BRCA1	P38398-1.2	R507F	Pathogenic	0.948
BRCA1	P38398-1.2	R507G	Pathogenic	0.989
BRCA1	P38398-1.2	R507H	Pathogenic	0.902
BRCA1	P38398-1.2	R507I	Pathogenic	0.959
BRCA1	P38398-1.2	R507K	Pathogenic	0.758
BRCA1	P38398-1.2	R507L	Pathogenic	0.942
BRCA1	P38398-1.2	R507M	Pathogenic	0.919
BRCA1	P38398-1.2	R507N	Pathogenic	0.939
BRCA1	P38398-1.2	R507P	Pathogenic	0.972
BRCA1	P38398-1.2	R507Q	Pathogenic	0.876
BRCA1	P38398-1.2	R507S	Pathogenic	0.973
BRCA1	P38398-1.2	R507T	Pathogenic	0.959
BRCA1	P38398-1.2	R507V	Pathogenic	0.973
BRCA1	P38398-1.2	R507W	Pathogenic	0.95
BRCA1	P38398-1.2	R507Y	Pathogenic	0.919
BRCA1	P38398-1.2	P508A	Neutral	0.004
BRCA1	P38398-1.2	P508C	Neutral	0.005
BRCA1	P38398-1.2	P508D	Neutral	0.002
BRCA1	P38398-1.2	P508E	Neutral	0.003
BRCA1	P38398-1.2	P508F	Neutral	0.017
BRCA1	P38398-1.2	P508G	Neutral	0.008
BRCA1	P38398-1.2	P508H	Neutral	0.006
BRCA1	P38398-1.2	P508I	Neutral	0.009
BRCA1	P38398-1.2	P508K	Neutral	0.006
BRCA1	P38398-1.2	P508L	Neutral	0.009
BRCA1	P38398-1.2	P508M	Neutral	0.007
BRCA1	P38398-1.2	P508N	Neutral	0.003
BRCA1	P38398-1.2	P508Q	Neutral	0.004
BRCA1	P38398-1.2	P508R	Neutral	0.011
BRCA1	P38398-1.2	P508S	Neutral	0.003
BRCA1	P38398-1.2	P508T	Neutral	0.002
BRCA1	P38398-1.2	P508V	Neutral	0.004
BRCA1	P38398-1.2	P508W	Neutral	0.031
BRCA1	P38398-1.2	P508Y	Neutral	0.014
BRCA1	P38398-1.2	T509A	Neutral	0.169
BRCA1	P38398-1.2	T509C	Neutral	0.16
BRCA1	P38398-1.2	T509D	Neutral	0.145
BRCA1	P38398-1.2	T509E	Neutral	0.188
BRCA1	P38398-1.2	T509F	Neutral	0.369
BRCA1	P38398-1.2	T509G	Neutral	0.391
BRCA1	P38398-1.2	T509H	Neutral	0.292
BRCA1	P38398-1.2	T509I	Neutral	0.242
BRCA1	P38398-1.2	T509K	Neutral	0.29
BRCA1	P38398-1.2	T509L	Neutral	0.242
BRCA1	P38398-1.2	T509M	Neutral	0.244
BRCA1	P38398-1.2	T509N	Neutral	0.107
BRCA1	P38398-1.2	T509P	Neutral	0.149
BRCA1	P38398-1.2	T509Q	Neutral	0.207
BRCA1	P38398-1.2	T509R	Neutral	0.353
BRCA1	P38398-1.2	T509S	Neutral	0.11
BRCA1	P38398-1.2	T509V	Neutral	0.128
BRCA1	P38398-1.2	T509W	Pathogenic	0.519
BRCA1	P38398-1.2	T509Y	Neutral	0.405
BRCA1	P38398-1.2	S510A	Neutral	0.176
BRCA1	P38398-1.2	S510C	Neutral	0.338
BRCA1	P38398-1.2	S510D	Neutral	0.285
BRCA1	P38398-1.2	S510E	Neutral	0.374
BRCA1	P38398-1.2	S510F	Pathogenic	0.683
BRCA1	P38398-1.2	S510G	Neutral	0.321
BRCA1	P38398-1.2	S510H	Pathogenic	0.514
BRCA1	P38398-1.2	S510I	Pathogenic	0.628
BRCA1	P38398-1.2	S510K	Pathogenic	0.514
BRCA1	P38398-1.2	S510L	Pathogenic	0.628
BRCA1	P38398-1.2	S510M	Pathogenic	0.542
BRCA1	P38398-1.2	S510N	Neutral	0.237
BRCA1	P38398-1.2	S510P	Neutral	0.36
BRCA1	P38398-1.2	S510Q	Neutral	0.402
BRCA1	P38398-1.2	S510R	Pathogenic	0.67
BRCA1	P38398-1.2	S510T	Neutral	0.226
BRCA1	P38398-1.2	S510V	Pathogenic	0.528
BRCA1	P38398-1.2	S510W	Pathogenic	0.851
BRCA1	P38398-1.2	S510Y	Pathogenic	0.714
BRCA1	P38398-1.2	G511A	Neutral	0.164
BRCA1	P38398-1.2	G511C	Neutral	0.468
BRCA1	P38398-1.2	G511D	Neutral	0.323
BRCA1	P38398-1.2	G511E	Pathogenic	0.506
BRCA1	P38398-1.2	G511F	Pathogenic	0.72
BRCA1	P38398-1.2	G511H	Pathogenic	0.558
BRCA1	P38398-1.2	G511I	Pathogenic	0.743
BRCA1	P38398-1.2	G511K	Pathogenic	0.645
BRCA1	P38398-1.2	G511L	Pathogenic	0.744
BRCA1	P38398-1.2	G511M	Pathogenic	0.67
BRCA1	P38398-1.2	G511N	Neutral	0.271
BRCA1	P38398-1.2	G511P	Neutral	0.402
BRCA1	P38398-1.2	G511Q	Pathogenic	0.536
BRCA1	P38398-1.2	G511R	Pathogenic	0.708
BRCA1	P38398-1.2	G511S	Neutral	0.184
BRCA1	P38398-1.2	G511T	Neutral	0.42
BRCA1	P38398-1.2	G511V	Pathogenic	0.572
BRCA1	P38398-1.2	G511W	Pathogenic	0.767
BRCA1	P38398-1.2	G511Y	Pathogenic	0.749
BRCA1	P38398-1.2	L512A	Pathogenic	0.992
BRCA1	P38398-1.2	L512C	Pathogenic	0.988
BRCA1	P38398-1.2	L512D	Pathogenic	0.995
BRCA1	P38398-1.2	L512E	Pathogenic	0.99
BRCA1	P38398-1.2	L512F	Pathogenic	0.97
BRCA1	P38398-1.2	L512G	Pathogenic	0.998
BRCA1	P38398-1.2	L512H	Pathogenic	0.988
BRCA1	P38398-1.2	L512I	Pathogenic	0.926
BRCA1	P38398-1.2	L512K	Pathogenic	0.985
BRCA1	P38398-1.2	L512M	Pathogenic	0.925
BRCA1	P38398-1.2	L512N	Pathogenic	0.993
BRCA1	P38398-1.2	L512P	Pathogenic	0.994
BRCA1	P38398-1.2	L512Q	Pathogenic	0.985
BRCA1	P38398-1.2	L512R	Pathogenic	0.989
BRCA1	P38398-1.2	L512S	Pathogenic	0.994
BRCA1	P38398-1.2	L512T	Pathogenic	0.986
BRCA1	P38398-1.2	L512V	Pathogenic	0.964
BRCA1	P38398-1.2	L512W	Pathogenic	0.992
BRCA1	P38398-1.2	L512Y	Pathogenic	0.982
BRCA1	P38398-1.2	H513A	Neutral	0.433
BRCA1	P38398-1.2	H513C	Neutral	0.416
BRCA1	P38398-1.2	H513D	Neutral	0.235
BRCA1	P38398-1.2	H513E	Neutral	0.126
BRCA1	P38398-1.2	H513F	Neutral	0.195
BRCA1	P38398-1.2	H513G	Pathogenic	0.539
BRCA1	P38398-1.2	H513I	Neutral	0.282
BRCA1	P38398-1.2	H513K	Neutral	0.197
BRCA1	P38398-1.2	H513L	Neutral	0.283
BRCA1	P38398-1.2	H513M	Neutral	0.217
BRCA1	P38398-1.2	H513N	Neutral	0.118
BRCA1	P38398-1.2	H513P	Neutral	0.313
BRCA1	P38398-1.2	H513Q	Neutral	0.115
BRCA1	P38398-1.2	H513R	Neutral	0.185
BRCA1	P38398-1.2	H513S	Neutral	0.318
BRCA1	P38398-1.2	H513T	Neutral	0.301
BRCA1	P38398-1.2	H513V	Neutral	0.317
BRCA1	P38398-1.2	H513W	Neutral	0.392
BRCA1	P38398-1.2	H513Y	Neutral	0.086
BRCA1	P38398-1.2	P514A	Pathogenic	0.989
BRCA1	P38398-1.2	P514C	Pathogenic	0.992
BRCA1	P38398-1.2	P514D	Pathogenic	0.982
BRCA1	P38398-1.2	P514E	Pathogenic	0.988
BRCA1	P38398-1.2	P514F	Pathogenic	0.998
BRCA1	P38398-1.2	P514G	Pathogenic	0.995
BRCA1	P38398-1.2	P514H	Pathogenic	0.993
BRCA1	P38398-1.2	P514I	Pathogenic	0.996
BRCA1	P38398-1.2	P514K	Pathogenic	0.993
BRCA1	P38398-1.2	P514L	Pathogenic	0.996
BRCA1	P38398-1.2	P514M	Pathogenic	0.994
BRCA1	P38398-1.2	P514N	Pathogenic	0.989
BRCA1	P38398-1.2	P514Q	Pathogenic	0.989
BRCA1	P38398-1.2	P514R	Pathogenic	0.996
BRCA1	P38398-1.2	P514S	Pathogenic	0.988
BRCA1	P38398-1.2	P514T	Pathogenic	0.983
BRCA1	P38398-1.2	P514V	Pathogenic	0.991
BRCA1	P38398-1.2	P514W	Pathogenic	0.999
BRCA1	P38398-1.2	P514Y	Pathogenic	0.997
BRCA1	P38398-1.2	E515A	Pathogenic	0.988
BRCA1	P38398-1.2	E515C	Pathogenic	0.994
BRCA1	P38398-1.2	E515D	Pathogenic	0.944
BRCA1	P38398-1.2	E515F	Pathogenic	0.992
BRCA1	P38398-1.2	E515G	Pathogenic	0.995
BRCA1	P38398-1.2	E515H	Pathogenic	0.966
BRCA1	P38398-1.2	E515I	Pathogenic	0.989
BRCA1	P38398-1.2	E515K	Pathogenic	0.967
BRCA1	P38398-1.2	E515L	Pathogenic	0.989
BRCA1	P38398-1.2	E515M	Pathogenic	0.985
BRCA1	P38398-1.2	E515N	Pathogenic	0.969
BRCA1	P38398-1.2	E515P	Pathogenic	0.981
BRCA1	P38398-1.2	E515Q	Pathogenic	0.927
BRCA1	P38398-1.2	E515R	Pathogenic	0.982
BRCA1	P38398-1.2	E515S	Pathogenic	0.981
BRCA1	P38398-1.2	E515T	Pathogenic	0.979
BRCA1	P38398-1.2	E515V	Pathogenic	0.981
BRCA1	P38398-1.2	E515W	Pathogenic	0.995
BRCA1	P38398-1.2	E515Y	Pathogenic	0.99
BRCA1	P38398-1.2	D516A	Pathogenic	0.994
BRCA1	P38398-1.2	D516C	Pathogenic	0.993
BRCA1	P38398-1.2	D516E	Pathogenic	0.971
BRCA1	P38398-1.2	D516F	Pathogenic	0.997
BRCA1	P38398-1.2	D516G	Pathogenic	0.994
BRCA1	P38398-1.2	D516H	Pathogenic	0.992
BRCA1	P38398-1.2	D516I	Pathogenic	0.996
BRCA1	P38398-1.2	D516K	Pathogenic	0.994
BRCA1	P38398-1.2	D516L	Pathogenic	0.997
BRCA1	P38398-1.2	D516M	Pathogenic	0.996
BRCA1	P38398-1.2	D516N	Pathogenic	0.973
BRCA1	P38398-1.2	D516P	Pathogenic	0.985
BRCA1	P38398-1.2	D516Q	Pathogenic	0.987
BRCA1	P38398-1.2	D516R	Pathogenic	0.997
BRCA1	P38398-1.2	D516S	Pathogenic	0.986
BRCA1	P38398-1.2	D516T	Pathogenic	0.986
BRCA1	P38398-1.2	D516V	Pathogenic	0.995
BRCA1	P38398-1.2	D516W	Pathogenic	0.999
BRCA1	P38398-1.2	D516Y	Pathogenic	0.998
BRCA1	P38398-1.2	F517A	Pathogenic	0.998
BRCA1	P38398-1.2	F517C	Pathogenic	0.997
BRCA1	P38398-1.2	F517D	Pathogenic	0.998
BRCA1	P38398-1.2	F517E	Pathogenic	0.997
BRCA1	P38398-1.2	F517G	Pathogenic	0.999
BRCA1	P38398-1.2	F517H	Pathogenic	0.992
BRCA1	P38398-1.2	F517I	Pathogenic	0.988
BRCA1	P38398-1.2	F517K	Pathogenic	0.994
BRCA1	P38398-1.2	F517L	Pathogenic	0.988
BRCA1	P38398-1.2	F517M	Pathogenic	0.988
BRCA1	P38398-1.2	F517N	Pathogenic	0.998
BRCA1	P38398-1.2	F517P	Pathogenic	0.999
BRCA1	P38398-1.2	F517Q	Pathogenic	0.997
BRCA1	P38398-1.2	F517R	Pathogenic	0.996
BRCA1	P38398-1.2	F517S	Pathogenic	0.998
BRCA1	P38398-1.2	F517T	Pathogenic	0.997
BRCA1	P38398-1.2	F517V	Pathogenic	0.994
BRCA1	P38398-1.2	F517W	Pathogenic	0.988
BRCA1	P38398-1.2	F517Y	Pathogenic	0.96
BRCA1	P38398-1.2	I518A	Pathogenic	0.995
BRCA1	P38398-1.2	I518C	Pathogenic	0.992
BRCA1	P38398-1.2	I518D	Pathogenic	0.996
BRCA1	P38398-1.2	I518E	Pathogenic	0.994
BRCA1	P38398-1.2	I518F	Pathogenic	0.98
BRCA1	P38398-1.2	I518G	Pathogenic	0.999
BRCA1	P38398-1.2	I518H	Pathogenic	0.992
BRCA1	P38398-1.2	I518K	Pathogenic	0.993
BRCA1	P38398-1.2	I518L	Pathogenic	0.949
BRCA1	P38398-1.2	I518M	Pathogenic	0.964
BRCA1	P38398-1.2	I518N	Pathogenic	0.995
BRCA1	P38398-1.2	I518P	Pathogenic	0.996
BRCA1	P38398-1.2	I518Q	Pathogenic	0.993
BRCA1	P38398-1.2	I518R	Pathogenic	0.995
BRCA1	P38398-1.2	I518S	Pathogenic	0.996
BRCA1	P38398-1.2	I518T	Pathogenic	0.991
BRCA1	P38398-1.2	I518V	Pathogenic	0.952
BRCA1	P38398-1.2	I518W	Pathogenic	0.996
BRCA1	P38398-1.2	I518Y	Pathogenic	0.988
BRCA1	P38398-1.2	K519A	Pathogenic	0.995
BRCA1	P38398-1.2	K519C	Pathogenic	0.996
BRCA1	P38398-1.2	K519D	Pathogenic	0.991
BRCA1	P38398-1.2	K519E	Pathogenic	0.973
BRCA1	P38398-1.2	K519F	Pathogenic	0.988
BRCA1	P38398-1.2	K519G	Pathogenic	0.998
BRCA1	P38398-1.2	K519H	Pathogenic	0.984
BRCA1	P38398-1.2	K519I	Pathogenic	0.991
BRCA1	P38398-1.2	K519L	Pathogenic	0.987
BRCA1	P38398-1.2	K519M	Pathogenic	0.981
BRCA1	P38398-1.2	K519N	Pathogenic	0.986
BRCA1	P38398-1.2	K519P	Pathogenic	0.991
BRCA1	P38398-1.2	K519Q	Pathogenic	0.97
BRCA1	P38398-1.2	K519R	Pathogenic	0.95
BRCA1	P38398-1.2	K519S	Pathogenic	0.991
BRCA1	P38398-1.2	K519T	Pathogenic	0.991
BRCA1	P38398-1.2	K519V	Pathogenic	0.991
BRCA1	P38398-1.2	K519W	Pathogenic	0.994
BRCA1	P38398-1.2	K519Y	Pathogenic	0.985
BRCA1	P38398-1.2	K520A	Pathogenic	0.802
BRCA1	P38398-1.2	K520C	Pathogenic	0.844
BRCA1	P38398-1.2	K520D	Pathogenic	0.708
BRCA1	P38398-1.2	K520E	Neutral	0.439
BRCA1	P38398-1.2	K520F	Pathogenic	0.643
BRCA1	P38398-1.2	K520G	Pathogenic	0.899
BRCA1	P38398-1.2	K520H	Pathogenic	0.567
BRCA1	P38398-1.2	K520I	Pathogenic	0.697
BRCA1	P38398-1.2	K520L	Pathogenic	0.615
BRCA1	P38398-1.2	K520M	Pathogenic	0.529
BRCA1	P38398-1.2	K520N	Pathogenic	0.601
BRCA1	P38398-1.2	K520P	Pathogenic	0.707
BRCA1	P38398-1.2	K520Q	Neutral	0.41
BRCA1	P38398-1.2	K520R	Neutral	0.291
BRCA1	P38398-1.2	K520S	Pathogenic	0.713
BRCA1	P38398-1.2	K520T	Pathogenic	0.695
BRCA1	P38398-1.2	K520V	Pathogenic	0.711
BRCA1	P38398-1.2	K520W	Pathogenic	0.769
BRCA1	P38398-1.2	K520Y	Pathogenic	0.592
BRCA1	P38398-1.2	A521C	Neutral	0.053
BRCA1	P38398-1.2	A521D	Neutral	0.114
BRCA1	P38398-1.2	A521E	Neutral	0.118
BRCA1	P38398-1.2	A521F	Neutral	0.254
BRCA1	P38398-1.2	A521G	Neutral	0.054
BRCA1	P38398-1.2	A521H	Neutral	0.193
BRCA1	P38398-1.2	A521I	Neutral	0.156
BRCA1	P38398-1.2	A521K	Neutral	0.192
BRCA1	P38398-1.2	A521L	Neutral	0.156
BRCA1	P38398-1.2	A521M	Neutral	0.158
BRCA1	P38398-1.2	A521N	Neutral	0.126
BRCA1	P38398-1.2	A521P	Neutral	0.082
BRCA1	P38398-1.2	A521Q	Neutral	0.131
BRCA1	P38398-1.2	A521R	Neutral	0.241
BRCA1	P38398-1.2	A521S	Neutral	0.029
BRCA1	P38398-1.2	A521T	Neutral	0.062
BRCA1	P38398-1.2	A521V	Neutral	0.079
BRCA1	P38398-1.2	A521W	Neutral	0.475
BRCA1	P38398-1.2	A521Y	Neutral	0.283
BRCA1	P38398-1.2	D522A	Pathogenic	0.964
BRCA1	P38398-1.2	D522C	Pathogenic	0.962
BRCA1	P38398-1.2	D522E	Pathogenic	0.849
BRCA1	P38398-1.2	D522F	Pathogenic	0.983
BRCA1	P38398-1.2	D522G	Pathogenic	0.966
BRCA1	P38398-1.2	D522H	Pathogenic	0.953
BRCA1	P38398-1.2	D522I	Pathogenic	0.979
BRCA1	P38398-1.2	D522K	Pathogenic	0.968
BRCA1	P38398-1.2	D522L	Pathogenic	0.985
BRCA1	P38398-1.2	D522M	Pathogenic	0.979
BRCA1	P38398-1.2	D522N	Pathogenic	0.858
BRCA1	P38398-1.2	D522P	Pathogenic	0.918
BRCA1	P38398-1.2	D522Q	Pathogenic	0.928
BRCA1	P38398-1.2	D522R	Pathogenic	0.983
BRCA1	P38398-1.2	D522S	Pathogenic	0.92
BRCA1	P38398-1.2	D522T	Pathogenic	0.92
BRCA1	P38398-1.2	D522V	Pathogenic	0.968
BRCA1	P38398-1.2	D522W	Pathogenic	0.994
BRCA1	P38398-1.2	D522Y	Pathogenic	0.986
BRCA1	P38398-1.2	L523A	Pathogenic	0.87
BRCA1	P38398-1.2	L523C	Pathogenic	0.816
BRCA1	P38398-1.2	L523D	Pathogenic	0.92
BRCA1	P38398-1.2	L523E	Pathogenic	0.843
BRCA1	P38398-1.2	L523F	Pathogenic	0.632
BRCA1	P38398-1.2	L523G	Pathogenic	0.968
BRCA1	P38398-1.2	L523H	Pathogenic	0.817
BRCA1	P38398-1.2	L523I	Neutral	0.394
BRCA1	P38398-1.2	L523K	Pathogenic	0.772
BRCA1	P38398-1.2	L523M	Neutral	0.392
BRCA1	P38398-1.2	L523N	Pathogenic	0.877
BRCA1	P38398-1.2	L523P	Pathogenic	0.893
BRCA1	P38398-1.2	L523Q	Pathogenic	0.771
BRCA1	P38398-1.2	L523R	Pathogenic	0.819
BRCA1	P38398-1.2	L523S	Pathogenic	0.893
BRCA1	P38398-1.2	L523T	Pathogenic	0.79
BRCA1	P38398-1.2	L523V	Pathogenic	0.586
BRCA1	P38398-1.2	L523W	Pathogenic	0.868
BRCA1	P38398-1.2	L523Y	Pathogenic	0.736
BRCA1	P38398-1.2	A524C	Neutral	0.081
BRCA1	P38398-1.2	A524D	Neutral	0.168
BRCA1	P38398-1.2	A524E	Neutral	0.173
BRCA1	P38398-1.2	A524F	Neutral	0.347
BRCA1	P38398-1.2	A524G	Neutral	0.081
BRCA1	P38398-1.2	A524H	Neutral	0.272
BRCA1	P38398-1.2	A524I	Neutral	0.224
BRCA1	P38398-1.2	A524K	Neutral	0.27
BRCA1	P38398-1.2	A524L	Neutral	0.224
BRCA1	P38398-1.2	A524M	Neutral	0.226
BRCA1	P38398-1.2	A524N	Neutral	0.184
BRCA1	P38398-1.2	A524P	Neutral	0.122
BRCA1	P38398-1.2	A524Q	Neutral	0.191
BRCA1	P38398-1.2	A524R	Neutral	0.33
BRCA1	P38398-1.2	A524S	Neutral	0.044
BRCA1	P38398-1.2	A524T	Neutral	0.094
BRCA1	P38398-1.2	A524V	Neutral	0.117
BRCA1	P38398-1.2	A524W	Pathogenic	0.585
BRCA1	P38398-1.2	A524Y	Neutral	0.381
BRCA1	P38398-1.2	V525A	Neutral	0.3
BRCA1	P38398-1.2	V525C	Neutral	0.29
BRCA1	P38398-1.2	V525D	Neutral	0.423
BRCA1	P38398-1.2	V525E	Neutral	0.29
BRCA1	P38398-1.2	V525F	Neutral	0.342
BRCA1	P38398-1.2	V525G	Pathogenic	0.659
BRCA1	P38398-1.2	V525H	Neutral	0.422
BRCA1	P38398-1.2	V525I	Neutral	0.087
BRCA1	P38398-1.2	V525K	Neutral	0.42
BRCA1	P38398-1.2	V525L	Neutral	0.164
BRCA1	P38398-1.2	V525M	Neutral	0.165
BRCA1	P38398-1.2	V525N	Neutral	0.397
BRCA1	P38398-1.2	V525P	Neutral	0.349
BRCA1	P38398-1.2	V525Q	Neutral	0.315
BRCA1	P38398-1.2	V525R	Pathogenic	0.581
BRCA1	P38398-1.2	V525S	Neutral	0.435
BRCA1	P38398-1.2	V525T	Neutral	0.193
BRCA1	P38398-1.2	V525W	Pathogenic	0.665
BRCA1	P38398-1.2	V525Y	Neutral	0.374
BRCA1	P38398-1.2	Q526A	Neutral	0.348
BRCA1	P38398-1.2	Q526C	Neutral	0.417
BRCA1	P38398-1.2	Q526D	Neutral	0.178
BRCA1	P38398-1.2	Q526E	Neutral	0.066
BRCA1	P38398-1.2	Q526F	Neutral	0.376
BRCA1	P38398-1.2	Q526G	Pathogenic	0.54
BRCA1	P38398-1.2	Q526H	Neutral	0.125
BRCA1	P38398-1.2	Q526I	Neutral	0.32
BRCA1	P38398-1.2	Q526K	Neutral	0.126
BRCA1	P38398-1.2	Q526L	Neutral	0.247
BRCA1	P38398-1.2	Q526M	Neutral	0.138
BRCA1	P38398-1.2	Q526N	Neutral	0.163
BRCA1	P38398-1.2	Q526P	Neutral	0.241
BRCA1	P38398-1.2	Q526R	Neutral	0.161
BRCA1	P38398-1.2	Q526S	Neutral	0.246
BRCA1	P38398-1.2	Q526T	Neutral	0.23
BRCA1	P38398-1.2	Q526V	Neutral	0.245
BRCA1	P38398-1.2	Q526W	Neutral	0.436
BRCA1	P38398-1.2	Q526Y	Neutral	0.252
BRCA1	P38398-1.2	K527A	Pathogenic	0.924
BRCA1	P38398-1.2	K527C	Pathogenic	0.942
BRCA1	P38398-1.2	K527D	Pathogenic	0.879
BRCA1	P38398-1.2	K527E	Pathogenic	0.701
BRCA1	P38398-1.2	K527F	Pathogenic	0.843
BRCA1	P38398-1.2	K527G	Pathogenic	0.964
BRCA1	P38398-1.2	K527H	Pathogenic	0.796
BRCA1	P38398-1.2	K527I	Pathogenic	0.873
BRCA1	P38398-1.2	K527L	Pathogenic	0.827
BRCA1	P38398-1.2	K527M	Pathogenic	0.77
BRCA1	P38398-1.2	K527N	Pathogenic	0.818
BRCA1	P38398-1.2	K527P	Pathogenic	0.878
BRCA1	P38398-1.2	K527Q	Pathogenic	0.675
BRCA1	P38398-1.2	K527R	Pathogenic	0.551
BRCA1	P38398-1.2	K527S	Pathogenic	0.881
BRCA1	P38398-1.2	K527T	Pathogenic	0.872
BRCA1	P38398-1.2	K527V	Pathogenic	0.88
BRCA1	P38398-1.2	K527W	Pathogenic	0.909
BRCA1	P38398-1.2	K527Y	Pathogenic	0.813
BRCA1	P38398-1.2	T528A	Pathogenic	0.796
BRCA1	P38398-1.2	T528C	Pathogenic	0.785
BRCA1	P38398-1.2	T528D	Pathogenic	0.764
BRCA1	P38398-1.2	T528E	Pathogenic	0.816
BRCA1	P38398-1.2	T528F	Pathogenic	0.918
BRCA1	P38398-1.2	T528G	Pathogenic	0.925
BRCA1	P38398-1.2	T528H	Pathogenic	0.888
BRCA1	P38398-1.2	T528I	Pathogenic	0.859
BRCA1	P38398-1.2	T528K	Pathogenic	0.887
BRCA1	P38398-1.2	T528L	Pathogenic	0.86
BRCA1	P38398-1.2	T528M	Pathogenic	0.861
BRCA1	P38398-1.2	T528N	Pathogenic	0.698
BRCA1	P38398-1.2	T528P	Pathogenic	0.77
BRCA1	P38398-1.2	T528Q	Pathogenic	0.833
BRCA1	P38398-1.2	T528R	Pathogenic	0.913
BRCA1	P38398-1.2	T528S	Pathogenic	0.703
BRCA1	P38398-1.2	T528V	Pathogenic	0.738
BRCA1	P38398-1.2	T528W	Pathogenic	0.954
BRCA1	P38398-1.2	T528Y	Pathogenic	0.929
BRCA1	P38398-1.2	P529A	Pathogenic	0.912
BRCA1	P38398-1.2	P529C	Pathogenic	0.934
BRCA1	P38398-1.2	P529D	Pathogenic	0.861
BRCA1	P38398-1.2	P529E	Pathogenic	0.903
BRCA1	P38398-1.2	P529F	Pathogenic	0.98
BRCA1	P38398-1.2	P529G	Pathogenic	0.958
BRCA1	P38398-1.2	P529H	Pathogenic	0.943
BRCA1	P38398-1.2	P529I	Pathogenic	0.964
BRCA1	P38398-1.2	P529K	Pathogenic	0.943
BRCA1	P38398-1.2	P529L	Pathogenic	0.964
BRCA1	P38398-1.2	P529M	Pathogenic	0.95
BRCA1	P38398-1.2	P529N	Pathogenic	0.909
BRCA1	P38398-1.2	P529Q	Pathogenic	0.913
BRCA1	P38398-1.2	P529R	Pathogenic	0.969
BRCA1	P38398-1.2	P529S	Pathogenic	0.9
BRCA1	P38398-1.2	P529T	Pathogenic	0.869
BRCA1	P38398-1.2	P529V	Pathogenic	0.926
BRCA1	P38398-1.2	P529W	Pathogenic	0.989
BRCA1	P38398-1.2	P529Y	Pathogenic	0.976
BRCA1	P38398-1.2	E530A	Pathogenic	0.86
BRCA1	P38398-1.2	E530C	Pathogenic	0.922
BRCA1	P38398-1.2	E530D	Pathogenic	0.552
BRCA1	P38398-1.2	E530F	Pathogenic	0.897
BRCA1	P38398-1.2	E530G	Pathogenic	0.931
BRCA1	P38398-1.2	E530H	Pathogenic	0.673
BRCA1	P38398-1.2	E530I	Pathogenic	0.872
BRCA1	P38398-1.2	E530K	Pathogenic	0.678
BRCA1	P38398-1.2	E530L	Pathogenic	0.872
BRCA1	P38398-1.2	E530M	Pathogenic	0.827
BRCA1	P38398-1.2	E530N	Pathogenic	0.696
BRCA1	P38398-1.2	E530P	Pathogenic	0.786
BRCA1	P38398-1.2	E530Q	Neutral	0.478
BRCA1	P38398-1.2	E530R	Pathogenic	0.802
BRCA1	P38398-1.2	E530S	Pathogenic	0.79
BRCA1	P38398-1.2	E530T	Pathogenic	0.776
BRCA1	P38398-1.2	E530V	Pathogenic	0.789
BRCA1	P38398-1.2	E530W	Pathogenic	0.941
BRCA1	P38398-1.2	E530Y	Pathogenic	0.875
BRCA1	P38398-1.2	M531A	Neutral	0.209
BRCA1	P38398-1.2	M531C	Neutral	0.15
BRCA1	P38398-1.2	M531D	Neutral	0.24
BRCA1	P38398-1.2	M531E	Neutral	0.128
BRCA1	P38398-1.2	M531F	Neutral	0.062
BRCA1	P38398-1.2	M531G	Neutral	0.454
BRCA1	P38398-1.2	M531H	Neutral	0.109
BRCA1	P38398-1.2	M531I	Neutral	0.035
BRCA1	P38398-1.2	M531K	Neutral	0.085
BRCA1	P38398-1.2	M531L	Neutral	0.025
BRCA1	P38398-1.2	M531N	Neutral	0.164
BRCA1	P38398-1.2	M531P	Neutral	0.187
BRCA1	P38398-1.2	M531Q	Neutral	0.06
BRCA1	P38398-1.2	M531R	Neutral	0.11
BRCA1	P38398-1.2	M531S	Neutral	0.187
BRCA1	P38398-1.2	M531T	Neutral	0.129
BRCA1	P38398-1.2	M531V	Neutral	0.053
BRCA1	P38398-1.2	M531W	Neutral	0.15
BRCA1	P38398-1.2	M531Y	Neutral	0.099
BRCA1	P38398-1.2	I532A	Neutral	0.253
BRCA1	P38398-1.2	I532C	Neutral	0.184
BRCA1	P38398-1.2	I532D	Neutral	0.287
BRCA1	P38398-1.2	I532E	Neutral	0.213
BRCA1	P38398-1.2	I532F	Neutral	0.08
BRCA1	P38398-1.2	I532G	Pathogenic	0.605
BRCA1	P38398-1.2	I532H	Neutral	0.184
BRCA1	P38398-1.2	I532K	Neutral	0.197
BRCA1	P38398-1.2	I532L	Neutral	0.032
BRCA1	P38398-1.2	I532M	Neutral	0.045
BRCA1	P38398-1.2	I532N	Neutral	0.266
BRCA1	P38398-1.2	I532P	Neutral	0.298
BRCA1	P38398-1.2	I532Q	Neutral	0.196
BRCA1	P38398-1.2	I532R	Neutral	0.247
BRCA1	P38398-1.2	I532S	Neutral	0.297
BRCA1	P38398-1.2	I532T	Neutral	0.16
BRCA1	P38398-1.2	I532V	Neutral	0.033
BRCA1	P38398-1.2	I532W	Neutral	0.324
BRCA1	P38398-1.2	I532Y	Neutral	0.124
BRCA1	P38398-1.2	N533A	Neutral	0.149
BRCA1	P38398-1.2	N533C	Neutral	0.14
BRCA1	P38398-1.2	N533D	Neutral	0.034
BRCA1	P38398-1.2	N533E	Neutral	0.057
BRCA1	P38398-1.2	N533F	Neutral	0.234
BRCA1	P38398-1.2	N533G	Neutral	0.115
BRCA1	P38398-1.2	N533H	Neutral	0.048
BRCA1	P38398-1.2	N533I	Neutral	0.193
BRCA1	P38398-1.2	N533K	Neutral	0.096
BRCA1	P38398-1.2	N533L	Neutral	0.193
BRCA1	P38398-1.2	N533M	Neutral	0.144
BRCA1	P38398-1.2	N533P	Neutral	0.094
BRCA1	P38398-1.2	N533Q	Neutral	0.063
BRCA1	P38398-1.2	N533R	Neutral	0.125
BRCA1	P38398-1.2	N533S	Neutral	0.049
BRCA1	P38398-1.2	N533T	Neutral	0.045
BRCA1	P38398-1.2	N533V	Neutral	0.137
BRCA1	P38398-1.2	N533W	Neutral	0.448
BRCA1	P38398-1.2	N533Y	Neutral	0.198
BRCA1	P38398-1.2	Q534A	Neutral	0.153
BRCA1	P38398-1.2	Q534C	Neutral	0.196
BRCA1	P38398-1.2	Q534D	Neutral	0.069
BRCA1	P38398-1.2	Q534E	Neutral	0.023
BRCA1	P38398-1.2	Q534F	Neutral	0.17
BRCA1	P38398-1.2	Q534G	Neutral	0.286
BRCA1	P38398-1.2	Q534H	Neutral	0.046
BRCA1	P38398-1.2	Q534I	Neutral	0.138
BRCA1	P38398-1.2	Q534K	Neutral	0.047
BRCA1	P38398-1.2	Q534L	Neutral	0.1
BRCA1	P38398-1.2	Q534M	Neutral	0.052
BRCA1	P38398-1.2	Q534N	Neutral	0.062
BRCA1	P38398-1.2	Q534P	Neutral	0.097
BRCA1	P38398-1.2	Q534R	Neutral	0.061
BRCA1	P38398-1.2	Q534S	Neutral	0.1
BRCA1	P38398-1.2	Q534T	Neutral	0.092
BRCA1	P38398-1.2	Q534V	Neutral	0.099
BRCA1	P38398-1.2	Q534W	Neutral	0.208
BRCA1	P38398-1.2	Q534Y	Neutral	0.103
BRCA1	P38398-1.2	G535A	Neutral	0.449
BRCA1	P38398-1.2	G535C	Pathogenic	0.785
BRCA1	P38398-1.2	G535D	Pathogenic	0.664
BRCA1	P38398-1.2	G535E	Pathogenic	0.81
BRCA1	P38398-1.2	G535F	Pathogenic	0.914
BRCA1	P38398-1.2	G535H	Pathogenic	0.84
BRCA1	P38398-1.2	G535I	Pathogenic	0.923
BRCA1	P38398-1.2	G535K	Pathogenic	0.883
BRCA1	P38398-1.2	G535L	Pathogenic	0.923
BRCA1	P38398-1.2	G535M	Pathogenic	0.894
BRCA1	P38398-1.2	G535N	Pathogenic	0.607
BRCA1	P38398-1.2	G535P	Pathogenic	0.736
BRCA1	P38398-1.2	G535Q	Pathogenic	0.828
BRCA1	P38398-1.2	G535R	Pathogenic	0.91
BRCA1	P38398-1.2	G535S	Neutral	0.483
BRCA1	P38398-1.2	G535T	Pathogenic	0.75
BRCA1	P38398-1.2	G535V	Pathogenic	0.847
BRCA1	P38398-1.2	G535W	Pathogenic	0.932
BRCA1	P38398-1.2	G535Y	Pathogenic	0.925
BRCA1	P38398-1.2	T536A	Pathogenic	0.741
BRCA1	P38398-1.2	T536C	Pathogenic	0.727
BRCA1	P38398-1.2	T536D	Pathogenic	0.703
BRCA1	P38398-1.2	T536E	Pathogenic	0.764
BRCA1	P38398-1.2	T536F	Pathogenic	0.891
BRCA1	P38398-1.2	T536G	Pathogenic	0.9
BRCA1	P38398-1.2	T536H	Pathogenic	0.853
BRCA1	P38398-1.2	T536I	Pathogenic	0.817
BRCA1	P38398-1.2	T536K	Pathogenic	0.852
BRCA1	P38398-1.2	T536L	Pathogenic	0.817
BRCA1	P38398-1.2	T536M	Pathogenic	0.819
BRCA1	P38398-1.2	T536N	Pathogenic	0.628
BRCA1	P38398-1.2	T536P	Pathogenic	0.71
BRCA1	P38398-1.2	T536Q	Pathogenic	0.785
BRCA1	P38398-1.2	T536R	Pathogenic	0.885
BRCA1	P38398-1.2	T536S	Pathogenic	0.634
BRCA1	P38398-1.2	T536V	Pathogenic	0.673
BRCA1	P38398-1.2	T536W	Pathogenic	0.938
BRCA1	P38398-1.2	T536Y	Pathogenic	0.905
BRCA1	P38398-1.2	N537A	Neutral	0.051
BRCA1	P38398-1.2	N537C	Neutral	0.048
BRCA1	P38398-1.2	N537D	Neutral	0.011
BRCA1	P38398-1.2	N537E	Neutral	0.018
BRCA1	P38398-1.2	N537F	Neutral	0.087
BRCA1	P38398-1.2	N537G	Neutral	0.039
BRCA1	P38398-1.2	N537H	Neutral	0.015
BRCA1	P38398-1.2	N537I	Neutral	0.069
BRCA1	P38398-1.2	N537K	Neutral	0.032
BRCA1	P38398-1.2	N537L	Neutral	0.069
BRCA1	P38398-1.2	N537M	Neutral	0.05
BRCA1	P38398-1.2	N537P	Neutral	0.031
BRCA1	P38398-1.2	N537Q	Neutral	0.02
BRCA1	P38398-1.2	N537R	Neutral	0.042
BRCA1	P38398-1.2	N537S	Neutral	0.016
BRCA1	P38398-1.2	N537T	Neutral	0.014
BRCA1	P38398-1.2	N537V	Neutral	0.047
BRCA1	P38398-1.2	N537W	Neutral	0.201
BRCA1	P38398-1.2	N537Y	Neutral	0.071
BRCA1	P38398-1.2	Q538A	Pathogenic	0.852
BRCA1	P38398-1.2	Q538C	Pathogenic	0.885
BRCA1	P38398-1.2	Q538D	Pathogenic	0.701
BRCA1	P38398-1.2	Q538E	Neutral	0.432
BRCA1	P38398-1.2	Q538F	Pathogenic	0.867
BRCA1	P38398-1.2	Q538G	Pathogenic	0.927
BRCA1	P38398-1.2	Q538H	Pathogenic	0.607
BRCA1	P38398-1.2	Q538I	Pathogenic	0.836
BRCA1	P38398-1.2	Q538K	Pathogenic	0.608
BRCA1	P38398-1.2	Q538L	Pathogenic	0.78
BRCA1	P38398-1.2	Q538M	Pathogenic	0.633
BRCA1	P38398-1.2	Q538N	Pathogenic	0.678
BRCA1	P38398-1.2	Q538P	Pathogenic	0.774
BRCA1	P38398-1.2	Q538R	Pathogenic	0.674
BRCA1	P38398-1.2	Q538S	Pathogenic	0.779
BRCA1	P38398-1.2	Q538T	Pathogenic	0.764
BRCA1	P38398-1.2	Q538V	Pathogenic	0.778
BRCA1	P38398-1.2	Q538W	Pathogenic	0.893
BRCA1	P38398-1.2	Q538Y	Pathogenic	0.784
BRCA1	P38398-1.2	T539A	Neutral	0.015
BRCA1	P38398-1.2	T539C	Neutral	0.014
BRCA1	P38398-1.2	T539D	Neutral	0.012
BRCA1	P38398-1.2	T539E	Neutral	0.016
BRCA1	P38398-1.2	T539F	Neutral	0.041
BRCA1	P38398-1.2	T539G	Neutral	0.044
BRCA1	P38398-1.2	T539H	Neutral	0.029
BRCA1	P38398-1.2	T539I	Neutral	0.023
BRCA1	P38398-1.2	T539K	Neutral	0.029
BRCA1	P38398-1.2	T539L	Neutral	0.023
BRCA1	P38398-1.2	T539M	Neutral	0.023
BRCA1	P38398-1.2	T539N	Neutral	0.009
BRCA1	P38398-1.2	T539P	Neutral	0.012
BRCA1	P38398-1.2	T539Q	Neutral	0.018
BRCA1	P38398-1.2	T539R	Neutral	0.038
BRCA1	P38398-1.2	T539S	Neutral	0.009
BRCA1	P38398-1.2	T539V	Neutral	0.011
BRCA1	P38398-1.2	T539W	Neutral	0.073
BRCA1	P38398-1.2	T539Y	Neutral	0.047
BRCA1	P38398-1.2	E540A	Neutral	0.394
BRCA1	P38398-1.2	E540C	Pathogenic	0.557
BRCA1	P38398-1.2	E540D	Neutral	0.115
BRCA1	P38398-1.2	E540F	Neutral	0.479
BRCA1	P38398-1.2	E540G	Pathogenic	0.59
BRCA1	P38398-1.2	E540H	Neutral	0.179
BRCA1	P38398-1.2	E540I	Neutral	0.418
BRCA1	P38398-1.2	E540K	Neutral	0.182
BRCA1	P38398-1.2	E540L	Neutral	0.419
BRCA1	P38398-1.2	E540M	Neutral	0.336
BRCA1	P38398-1.2	E540N	Neutral	0.195
BRCA1	P38398-1.2	E540P	Neutral	0.279
BRCA1	P38398-1.2	E540Q	Neutral	0.088
BRCA1	P38398-1.2	E540R	Neutral	0.3
BRCA1	P38398-1.2	E540S	Neutral	0.285
BRCA1	P38398-1.2	E540T	Neutral	0.268
BRCA1	P38398-1.2	E540V	Neutral	0.284
BRCA1	P38398-1.2	E540W	Pathogenic	0.629
BRCA1	P38398-1.2	E540Y	Neutral	0.426
BRCA1	P38398-1.2	Q541A	Neutral	0.123
BRCA1	P38398-1.2	Q541C	Neutral	0.158
BRCA1	P38398-1.2	Q541D	Neutral	0.054
BRCA1	P38398-1.2	Q541E	Neutral	0.018
BRCA1	P38398-1.2	Q541F	Neutral	0.136
BRCA1	P38398-1.2	Q541G	Neutral	0.236
BRCA1	P38398-1.2	Q541H	Neutral	0.036
BRCA1	P38398-1.2	Q541I	Neutral	0.11
BRCA1	P38398-1.2	Q541K	Neutral	0.036
BRCA1	P38398-1.2	Q541L	Neutral	0.079
BRCA1	P38398-1.2	Q541M	Neutral	0.04
BRCA1	P38398-1.2	Q541N	Neutral	0.049
BRCA1	P38398-1.2	Q541P	Neutral	0.077
BRCA1	P38398-1.2	Q541R	Neutral	0.048
BRCA1	P38398-1.2	Q541S	Neutral	0.079
BRCA1	P38398-1.2	Q541T	Neutral	0.073
BRCA1	P38398-1.2	Q541V	Neutral	0.078
BRCA1	P38398-1.2	Q541W	Neutral	0.168
BRCA1	P38398-1.2	Q541Y	Neutral	0.081
BRCA1	P38398-1.2	N542A	Pathogenic	0.544
BRCA1	P38398-1.2	N542C	Pathogenic	0.526
BRCA1	P38398-1.2	N542D	Neutral	0.192
BRCA1	P38398-1.2	N542E	Neutral	0.291
BRCA1	P38398-1.2	N542F	Pathogenic	0.676
BRCA1	P38398-1.2	N542G	Neutral	0.469
BRCA1	P38398-1.2	N542H	Neutral	0.256
BRCA1	P38398-1.2	N542I	Pathogenic	0.62
BRCA1	P38398-1.2	N542K	Neutral	0.421
BRCA1	P38398-1.2	N542L	Pathogenic	0.621
BRCA1	P38398-1.2	N542M	Pathogenic	0.534
BRCA1	P38398-1.2	N542P	Neutral	0.415
BRCA1	P38398-1.2	N542Q	Neutral	0.313
BRCA1	P38398-1.2	N542R	Neutral	0.492
BRCA1	P38398-1.2	N542S	Neutral	0.261
BRCA1	P38398-1.2	N542T	Neutral	0.245
BRCA1	P38398-1.2	N542V	Pathogenic	0.52
BRCA1	P38398-1.2	N542W	Pathogenic	0.847
BRCA1	P38398-1.2	N542Y	Pathogenic	0.627
BRCA1	P38398-1.2	G543A	Neutral	0.085
BRCA1	P38398-1.2	G543C	Neutral	0.293
BRCA1	P38398-1.2	G543D	Neutral	0.184
BRCA1	P38398-1.2	G543E	Neutral	0.326
BRCA1	P38398-1.2	G543F	Pathogenic	0.548
BRCA1	P38398-1.2	G543H	Neutral	0.374
BRCA1	P38398-1.2	G543I	Pathogenic	0.578
BRCA1	P38398-1.2	G543K	Neutral	0.461
BRCA1	P38398-1.2	G543L	Pathogenic	0.578
BRCA1	P38398-1.2	G543M	Neutral	0.49
BRCA1	P38398-1.2	G543N	Neutral	0.149
BRCA1	P38398-1.2	G543P	Neutral	0.241
BRCA1	P38398-1.2	G543Q	Neutral	0.353
BRCA1	P38398-1.2	G543R	Pathogenic	0.533
BRCA1	P38398-1.2	G543S	Neutral	0.096
BRCA1	P38398-1.2	G543T	Neutral	0.255
BRCA1	P38398-1.2	G543V	Neutral	0.387
BRCA1	P38398-1.2	G543W	Pathogenic	0.609
BRCA1	P38398-1.2	G543Y	Pathogenic	0.585
BRCA1	P38398-1.2	Q544A	Neutral	0.398
BRCA1	P38398-1.2	Q544C	Neutral	0.47
BRCA1	P38398-1.2	Q544D	Neutral	0.212
BRCA1	P38398-1.2	Q544E	Neutral	0.08
BRCA1	P38398-1.2	Q544F	Neutral	0.427
BRCA1	P38398-1.2	Q544G	Pathogenic	0.593
BRCA1	P38398-1.2	Q544H	Neutral	0.151
BRCA1	P38398-1.2	Q544I	Neutral	0.369
BRCA1	P38398-1.2	Q544K	Neutral	0.151
BRCA1	P38398-1.2	Q544L	Neutral	0.289
BRCA1	P38398-1.2	Q544M	Neutral	0.165
BRCA1	P38398-1.2	Q544N	Neutral	0.195
BRCA1	P38398-1.2	Q544P	Neutral	0.282
BRCA1	P38398-1.2	Q544R	Neutral	0.192
BRCA1	P38398-1.2	Q544S	Neutral	0.288
BRCA1	P38398-1.2	Q544T	Neutral	0.271
BRCA1	P38398-1.2	Q544V	Neutral	0.287
BRCA1	P38398-1.2	Q544W	Neutral	0.489
BRCA1	P38398-1.2	Q544Y	Neutral	0.295
BRCA1	P38398-1.2	V545A	Neutral	0.268
BRCA1	P38398-1.2	V545C	Neutral	0.259
BRCA1	P38398-1.2	V545D	Neutral	0.386
BRCA1	P38398-1.2	V545E	Neutral	0.259
BRCA1	P38398-1.2	V545F	Neutral	0.308
BRCA1	P38398-1.2	V545G	Pathogenic	0.623
BRCA1	P38398-1.2	V545H	Neutral	0.384
BRCA1	P38398-1.2	V545I	Neutral	0.075
BRCA1	P38398-1.2	V545K	Neutral	0.383
BRCA1	P38398-1.2	V545L	Neutral	0.144
BRCA1	P38398-1.2	V545M	Neutral	0.145
BRCA1	P38398-1.2	V545N	Neutral	0.36
BRCA1	P38398-1.2	V545P	Neutral	0.315
BRCA1	P38398-1.2	V545Q	Neutral	0.283
BRCA1	P38398-1.2	V545R	Pathogenic	0.543
BRCA1	P38398-1.2	V545S	Neutral	0.397
BRCA1	P38398-1.2	V545T	Neutral	0.17
BRCA1	P38398-1.2	V545W	Pathogenic	0.629
BRCA1	P38398-1.2	V545Y	Neutral	0.338
BRCA1	P38398-1.2	M546A	Neutral	0.252
BRCA1	P38398-1.2	M546C	Neutral	0.183
BRCA1	P38398-1.2	M546D	Neutral	0.286
BRCA1	P38398-1.2	M546E	Neutral	0.157
BRCA1	P38398-1.2	M546F	Neutral	0.078
BRCA1	P38398-1.2	M546G	Pathogenic	0.513
BRCA1	P38398-1.2	M546H	Neutral	0.134
BRCA1	P38398-1.2	M546I	Neutral	0.044
BRCA1	P38398-1.2	M546K	Neutral	0.106
BRCA1	P38398-1.2	M546L	Neutral	0.031
BRCA1	P38398-1.2	M546N	Neutral	0.2
BRCA1	P38398-1.2	M546P	Neutral	0.226
BRCA1	P38398-1.2	M546Q	Neutral	0.075
BRCA1	P38398-1.2	M546R	Neutral	0.136
BRCA1	P38398-1.2	M546S	Neutral	0.226
BRCA1	P38398-1.2	M546T	Neutral	0.159
BRCA1	P38398-1.2	M546V	Neutral	0.066
BRCA1	P38398-1.2	M546W	Neutral	0.184
BRCA1	P38398-1.2	M546Y	Neutral	0.123
BRCA1	P38398-1.2	N547A	Neutral	0.229
BRCA1	P38398-1.2	N547C	Neutral	0.217
BRCA1	P38398-1.2	N547D	Neutral	0.056
BRCA1	P38398-1.2	N547E	Neutral	0.093
BRCA1	P38398-1.2	N547F	Neutral	0.341
BRCA1	P38398-1.2	N547G	Neutral	0.18
BRCA1	P38398-1.2	N547H	Neutral	0.079
BRCA1	P38398-1.2	N547I	Neutral	0.289
BRCA1	P38398-1.2	N547K	Neutral	0.153
BRCA1	P38398-1.2	N547L	Neutral	0.289
BRCA1	P38398-1.2	N547M	Neutral	0.222
BRCA1	P38398-1.2	N547P	Neutral	0.15
BRCA1	P38398-1.2	N547Q	Neutral	0.102
BRCA1	P38398-1.2	N547R	Neutral	0.194
BRCA1	P38398-1.2	N547S	Neutral	0.081
BRCA1	P38398-1.2	N547T	Neutral	0.075
BRCA1	P38398-1.2	N547V	Neutral	0.212
BRCA1	P38398-1.2	N547W	Pathogenic	0.579
BRCA1	P38398-1.2	N547Y	Neutral	0.295
BRCA1	P38398-1.2	I548A	Pathogenic	0.616
BRCA1	P38398-1.2	I548C	Pathogenic	0.516
BRCA1	P38398-1.2	I548D	Pathogenic	0.656
BRCA1	P38398-1.2	I548E	Pathogenic	0.562
BRCA1	P38398-1.2	I548F	Neutral	0.292
BRCA1	P38398-1.2	I548G	Pathogenic	0.879
BRCA1	P38398-1.2	I548H	Pathogenic	0.516
BRCA1	P38398-1.2	I548K	Pathogenic	0.538
BRCA1	P38398-1.2	I548L	Neutral	0.135
BRCA1	P38398-1.2	I548M	Neutral	0.182
BRCA1	P38398-1.2	I548N	Pathogenic	0.632
BRCA1	P38398-1.2	I548P	Pathogenic	0.668
BRCA1	P38398-1.2	I548Q	Pathogenic	0.537
BRCA1	P38398-1.2	I548R	Pathogenic	0.609
BRCA1	P38398-1.2	I548S	Pathogenic	0.667
BRCA1	P38398-1.2	I548T	Neutral	0.474
BRCA1	P38398-1.2	I548V	Neutral	0.141
BRCA1	P38398-1.2	I548W	Pathogenic	0.694
BRCA1	P38398-1.2	I548Y	Neutral	0.401
BRCA1	P38398-1.2	T549A	Neutral	0.069
BRCA1	P38398-1.2	T549C	Neutral	0.065
BRCA1	P38398-1.2	T549D	Neutral	0.058
BRCA1	P38398-1.2	T549E	Neutral	0.078
BRCA1	P38398-1.2	T549F	Neutral	0.176
BRCA1	P38398-1.2	T549G	Neutral	0.189
BRCA1	P38398-1.2	T549H	Neutral	0.131
BRCA1	P38398-1.2	T549I	Neutral	0.104
BRCA1	P38398-1.2	T549K	Neutral	0.13
BRCA1	P38398-1.2	T549L	Neutral	0.104
BRCA1	P38398-1.2	T549M	Neutral	0.105
BRCA1	P38398-1.2	T549N	Neutral	0.042
BRCA1	P38398-1.2	T549P	Neutral	0.06
BRCA1	P38398-1.2	T549Q	Neutral	0.087
BRCA1	P38398-1.2	T549R	Neutral	0.166
BRCA1	P38398-1.2	T549S	Neutral	0.043
BRCA1	P38398-1.2	T549V	Neutral	0.051
BRCA1	P38398-1.2	T549W	Neutral	0.282
BRCA1	P38398-1.2	T549Y	Neutral	0.198
BRCA1	P38398-1.2	N550A	Neutral	0.113
BRCA1	P38398-1.2	N550C	Neutral	0.106
BRCA1	P38398-1.2	N550D	Neutral	0.025
BRCA1	P38398-1.2	N550E	Neutral	0.042
BRCA1	P38398-1.2	N550F	Neutral	0.182
BRCA1	P38398-1.2	N550G	Neutral	0.086
BRCA1	P38398-1.2	N550H	Neutral	0.035
BRCA1	P38398-1.2	N550I	Neutral	0.148
BRCA1	P38398-1.2	N550K	Neutral	0.072
BRCA1	P38398-1.2	N550L	Neutral	0.148
BRCA1	P38398-1.2	N550M	Neutral	0.109
BRCA1	P38398-1.2	N550P	Neutral	0.07
BRCA1	P38398-1.2	N550Q	Neutral	0.046
BRCA1	P38398-1.2	N550R	Neutral	0.094
BRCA1	P38398-1.2	N550S	Neutral	0.036
BRCA1	P38398-1.2	N550T	Neutral	0.033
BRCA1	P38398-1.2	N550V	Neutral	0.103
BRCA1	P38398-1.2	N550W	Neutral	0.371
BRCA1	P38398-1.2	N550Y	Neutral	0.152
BRCA1	P38398-1.2	S551A	Neutral	0.003
BRCA1	P38398-1.2	S551C	Neutral	0.007
BRCA1	P38398-1.2	S551D	Neutral	0.005
BRCA1	P38398-1.2	S551E	Neutral	0.008
BRCA1	P38398-1.2	S551F	Neutral	0.029
BRCA1	P38398-1.2	S551G	Neutral	0.006
BRCA1	P38398-1.2	S551H	Neutral	0.014
BRCA1	P38398-1.2	S551I	Neutral	0.023
BRCA1	P38398-1.2	S551K	Neutral	0.014
BRCA1	P38398-1.2	S551L	Neutral	0.023
BRCA1	P38398-1.2	S551M	Neutral	0.016
BRCA1	P38398-1.2	S551N	Neutral	0.004
BRCA1	P38398-1.2	S551P	Neutral	0.008
BRCA1	P38398-1.2	S551Q	Neutral	0.009
BRCA1	P38398-1.2	S551R	Neutral	0.027
BRCA1	P38398-1.2	S551T	Neutral	0.004
BRCA1	P38398-1.2	S551V	Neutral	0.015
BRCA1	P38398-1.2	S551W	Neutral	0.073
BRCA1	P38398-1.2	S551Y	Neutral	0.033
BRCA1	P38398-1.2	G552A	Neutral	0.06
BRCA1	P38398-1.2	G552C	Neutral	0.222
BRCA1	P38398-1.2	G552D	Neutral	0.134
BRCA1	P38398-1.2	G552E	Neutral	0.25
BRCA1	P38398-1.2	G552F	Neutral	0.455
BRCA1	P38398-1.2	G552H	Neutral	0.291
BRCA1	P38398-1.2	G552I	Neutral	0.485
BRCA1	P38398-1.2	G552K	Neutral	0.371
BRCA1	P38398-1.2	G552L	Neutral	0.486
BRCA1	P38398-1.2	G552M	Neutral	0.398
BRCA1	P38398-1.2	G552N	Neutral	0.108
BRCA1	P38398-1.2	G552P	Neutral	0.179
BRCA1	P38398-1.2	G552Q	Neutral	0.273
BRCA1	P38398-1.2	G552R	Neutral	0.44
BRCA1	P38398-1.2	G552S	Neutral	0.068
BRCA1	P38398-1.2	G552T	Neutral	0.191
BRCA1	P38398-1.2	G552V	Neutral	0.303
BRCA1	P38398-1.2	G552W	Pathogenic	0.517
BRCA1	P38398-1.2	G552Y	Neutral	0.492
BRCA1	P38398-1.2	H553A	Neutral	0.162
BRCA1	P38398-1.2	H553C	Neutral	0.152
BRCA1	P38398-1.2	H553D	Neutral	0.072
BRCA1	P38398-1.2	H553E	Neutral	0.035
BRCA1	P38398-1.2	H553F	Neutral	0.058
BRCA1	P38398-1.2	H553G	Neutral	0.227
BRCA1	P38398-1.2	H553I	Neutral	0.09
BRCA1	P38398-1.2	H553K	Neutral	0.058
BRCA1	P38398-1.2	H553L	Neutral	0.09
BRCA1	P38398-1.2	H553M	Neutral	0.065
BRCA1	P38398-1.2	H553N	Neutral	0.033
BRCA1	P38398-1.2	H553P	Neutral	0.103
BRCA1	P38398-1.2	H553Q	Neutral	0.032
BRCA1	P38398-1.2	H553R	Neutral	0.054
BRCA1	P38398-1.2	H553S	Neutral	0.105
BRCA1	P38398-1.2	H553T	Neutral	0.098
BRCA1	P38398-1.2	H553V	Neutral	0.105
BRCA1	P38398-1.2	H553W	Neutral	0.14
BRCA1	P38398-1.2	H553Y	Neutral	0.023
BRCA1	P38398-1.2	E554A	Pathogenic	0.833
BRCA1	P38398-1.2	E554C	Pathogenic	0.906
BRCA1	P38398-1.2	E554D	Neutral	0.5
BRCA1	P38398-1.2	E554F	Pathogenic	0.876
BRCA1	P38398-1.2	E554G	Pathogenic	0.917
BRCA1	P38398-1.2	E554H	Pathogenic	0.626
BRCA1	P38398-1.2	E554I	Pathogenic	0.846
BRCA1	P38398-1.2	E554K	Pathogenic	0.631
BRCA1	P38398-1.2	E554L	Pathogenic	0.847
BRCA1	P38398-1.2	E554M	Pathogenic	0.795
BRCA1	P38398-1.2	E554N	Pathogenic	0.65
BRCA1	P38398-1.2	E554P	Pathogenic	0.748
BRCA1	P38398-1.2	E554Q	Neutral	0.427
BRCA1	P38398-1.2	E554R	Pathogenic	0.766
BRCA1	P38398-1.2	E554S	Pathogenic	0.753
BRCA1	P38398-1.2	E554T	Pathogenic	0.737
BRCA1	P38398-1.2	E554V	Pathogenic	0.752
BRCA1	P38398-1.2	E554W	Pathogenic	0.929
BRCA1	P38398-1.2	E554Y	Pathogenic	0.85
BRCA1	P38398-1.2	N555A	Neutral	0.4
BRCA1	P38398-1.2	N555C	Neutral	0.383
BRCA1	P38398-1.2	N555D	Neutral	0.118
BRCA1	P38398-1.2	N555E	Neutral	0.187
BRCA1	P38398-1.2	N555F	Pathogenic	0.538
BRCA1	P38398-1.2	N555G	Neutral	0.331
BRCA1	P38398-1.2	N555H	Neutral	0.161
BRCA1	P38398-1.2	N555I	Neutral	0.477
BRCA1	P38398-1.2	N555K	Neutral	0.289
BRCA1	P38398-1.2	N555L	Neutral	0.478
BRCA1	P38398-1.2	N555M	Neutral	0.391
BRCA1	P38398-1.2	N555P	Neutral	0.284
BRCA1	P38398-1.2	N555Q	Neutral	0.203
BRCA1	P38398-1.2	N555R	Neutral	0.352
BRCA1	P38398-1.2	N555S	Neutral	0.165
BRCA1	P38398-1.2	N555T	Neutral	0.153
BRCA1	P38398-1.2	N555V	Neutral	0.377
BRCA1	P38398-1.2	N555W	Pathogenic	0.756
BRCA1	P38398-1.2	N555Y	Neutral	0.485
BRCA1	P38398-1.2	K556A	Neutral	0.121
BRCA1	P38398-1.2	K556C	Neutral	0.156
BRCA1	P38398-1.2	K556D	Neutral	0.076
BRCA1	P38398-1.2	K556E	Neutral	0.026
BRCA1	P38398-1.2	K556F	Neutral	0.058
BRCA1	P38398-1.2	K556G	Neutral	0.234
BRCA1	P38398-1.2	K556H	Neutral	0.043
BRCA1	P38398-1.2	K556I	Neutral	0.073
BRCA1	P38398-1.2	K556L	Neutral	0.052
BRCA1	P38398-1.2	K556M	Neutral	0.037
BRCA1	P38398-1.2	K556N	Neutral	0.049
BRCA1	P38398-1.2	K556P	Neutral	0.076
BRCA1	P38398-1.2	K556Q	Neutral	0.023
BRCA1	P38398-1.2	K556R	Neutral	0.014
BRCA1	P38398-1.2	K556S	Neutral	0.078
BRCA1	P38398-1.2	K556T	Neutral	0.072
BRCA1	P38398-1.2	K556V	Neutral	0.077
BRCA1	P38398-1.2	K556W	Neutral	0.102
BRCA1	P38398-1.2	K556Y	Neutral	0.047
BRCA1	P38398-1.2	T557A	Neutral	0.156
BRCA1	P38398-1.2	T557C	Neutral	0.147
BRCA1	P38398-1.2	T557D	Neutral	0.133
BRCA1	P38398-1.2	T557E	Neutral	0.173
BRCA1	P38398-1.2	T557F	Neutral	0.347
BRCA1	P38398-1.2	T557G	Neutral	0.368
BRCA1	P38398-1.2	T557H	Neutral	0.272
BRCA1	P38398-1.2	T557I	Neutral	0.224
BRCA1	P38398-1.2	T557K	Neutral	0.271
BRCA1	P38398-1.2	T557L	Neutral	0.224
BRCA1	P38398-1.2	T557M	Neutral	0.226
BRCA1	P38398-1.2	T557N	Neutral	0.098
BRCA1	P38398-1.2	T557P	Neutral	0.137
BRCA1	P38398-1.2	T557Q	Neutral	0.191
BRCA1	P38398-1.2	T557R	Neutral	0.331
BRCA1	P38398-1.2	T557S	Neutral	0.101
BRCA1	P38398-1.2	T557V	Neutral	0.117
BRCA1	P38398-1.2	T557W	Neutral	0.495
BRCA1	P38398-1.2	T557Y	Neutral	0.381
BRCA1	P38398-1.2	K558A	Neutral	0.397
BRCA1	P38398-1.2	K558C	Neutral	0.469
BRCA1	P38398-1.2	K558D	Neutral	0.283
BRCA1	P38398-1.2	K558E	Neutral	0.113
BRCA1	P38398-1.2	K558F	Neutral	0.226
BRCA1	P38398-1.2	K558G	Pathogenic	0.592
BRCA1	P38398-1.2	K558H	Neutral	0.175
BRCA1	P38398-1.2	K558I	Neutral	0.272
BRCA1	P38398-1.2	K558L	Neutral	0.206
BRCA1	P38398-1.2	K558M	Neutral	0.154
BRCA1	P38398-1.2	K558N	Neutral	0.196
BRCA1	P38398-1.2	K558P	Neutral	0.281
BRCA1	P38398-1.2	K558Q	Neutral	0.102
BRCA1	P38398-1.2	K558R	Neutral	0.063
BRCA1	P38398-1.2	K558S	Neutral	0.287
BRCA1	P38398-1.2	K558T	Neutral	0.27
BRCA1	P38398-1.2	K558V	Neutral	0.286
BRCA1	P38398-1.2	K558W	Neutral	0.351
BRCA1	P38398-1.2	K558Y	Neutral	0.191
BRCA1	P38398-1.2	G559A	Neutral	0.056
BRCA1	P38398-1.2	G559C	Neutral	0.21
BRCA1	P38398-1.2	G559D	Neutral	0.126
BRCA1	P38398-1.2	G559E	Neutral	0.237
BRCA1	P38398-1.2	G559F	Neutral	0.437
BRCA1	P38398-1.2	G559H	Neutral	0.277
BRCA1	P38398-1.2	G559I	Neutral	0.467
BRCA1	P38398-1.2	G559K	Neutral	0.354
BRCA1	P38398-1.2	G559L	Neutral	0.467
BRCA1	P38398-1.2	G559M	Neutral	0.381
BRCA1	P38398-1.2	G559N	Neutral	0.101
BRCA1	P38398-1.2	G559P	Neutral	0.169
BRCA1	P38398-1.2	G559Q	Neutral	0.259
BRCA1	P38398-1.2	G559R	Neutral	0.423
BRCA1	P38398-1.2	G559S	Neutral	0.064
BRCA1	P38398-1.2	G559T	Neutral	0.18
BRCA1	P38398-1.2	G559V	Neutral	0.288
BRCA1	P38398-1.2	G559W	Neutral	0.499
BRCA1	P38398-1.2	G559Y	Neutral	0.474
BRCA1	P38398-1.2	D560A	Neutral	0.329
BRCA1	P38398-1.2	D560C	Neutral	0.314
BRCA1	P38398-1.2	D560E	Neutral	0.093
BRCA1	P38398-1.2	D560F	Pathogenic	0.517
BRCA1	P38398-1.2	D560G	Neutral	0.343
BRCA1	P38398-1.2	D560H	Neutral	0.268
BRCA1	P38398-1.2	D560I	Neutral	0.456
BRCA1	P38398-1.2	D560K	Neutral	0.351
BRCA1	P38398-1.2	D560L	Pathogenic	0.547
BRCA1	P38398-1.2	D560M	Neutral	0.459
BRCA1	P38398-1.2	D560N	Neutral	0.099
BRCA1	P38398-1.2	D560P	Neutral	0.169
BRCA1	P38398-1.2	D560Q	Neutral	0.19
BRCA1	P38398-1.2	D560R	Pathogenic	0.509
BRCA1	P38398-1.2	D560S	Neutral	0.173
BRCA1	P38398-1.2	D560T	Neutral	0.173
BRCA1	P38398-1.2	D560V	Neutral	0.357
BRCA1	P38398-1.2	D560W	Pathogenic	0.74
BRCA1	P38398-1.2	D560Y	Pathogenic	0.554
BRCA1	P38398-1.2	S561A	Neutral	0.001
BRCA1	P38398-1.2	S561C	Neutral	0.002
BRCA1	P38398-1.2	S561D	Neutral	0.001
BRCA1	P38398-1.2	S561E	Neutral	0.002
BRCA1	P38398-1.2	S561F	Neutral	0.007
BRCA1	P38398-1.2	S561G	Neutral	0.001
BRCA1	P38398-1.2	S561H	Neutral	0.003
BRCA1	P38398-1.2	S561I	Neutral	0.005
BRCA1	P38398-1.2	S561K	Neutral	0.003
BRCA1	P38398-1.2	S561L	Neutral	0.005
BRCA1	P38398-1.2	S561M	Neutral	0.004
BRCA1	P38398-1.2	S561N	Neutral	0.001
BRCA1	P38398-1.2	S561P	Neutral	0.002
BRCA1	P38398-1.2	S561Q	Neutral	0.002
BRCA1	P38398-1.2	S561R	Neutral	0.006
BRCA1	P38398-1.2	S561T	Neutral	0.001
BRCA1	P38398-1.2	S561V	Neutral	0.003
BRCA1	P38398-1.2	S561W	Neutral	0.017
BRCA1	P38398-1.2	S561Y	Neutral	0.008
BRCA1	P38398-1.2	I562A	Neutral	0.146
BRCA1	P38398-1.2	I562C	Neutral	0.102
BRCA1	P38398-1.2	I562D	Neutral	0.169
BRCA1	P38398-1.2	I562E	Neutral	0.121
BRCA1	P38398-1.2	I562F	Neutral	0.042
BRCA1	P38398-1.2	I562G	Neutral	0.436
BRCA1	P38398-1.2	I562H	Neutral	0.102
BRCA1	P38398-1.2	I562K	Neutral	0.111
BRCA1	P38398-1.2	I562L	Neutral	0.016
BRCA1	P38398-1.2	I562M	Neutral	0.023
BRCA1	P38398-1.2	I562N	Neutral	0.155
BRCA1	P38398-1.2	I562P	Neutral	0.177
BRCA1	P38398-1.2	I562Q	Neutral	0.11
BRCA1	P38398-1.2	I562R	Neutral	0.143
BRCA1	P38398-1.2	I562S	Neutral	0.177
BRCA1	P38398-1.2	I562T	Neutral	0.088
BRCA1	P38398-1.2	I562V	Neutral	0.017
BRCA1	P38398-1.2	I562W	Neutral	0.195
BRCA1	P38398-1.2	I562Y	Neutral	0.067
BRCA1	P38398-1.2	Q563A	Pathogenic	0.927
BRCA1	P38398-1.2	Q563C	Pathogenic	0.944
BRCA1	P38398-1.2	Q563D	Pathogenic	0.838
BRCA1	P38398-1.2	Q563E	Pathogenic	0.626
BRCA1	P38398-1.2	Q563F	Pathogenic	0.935
BRCA1	P38398-1.2	Q563G	Pathogenic	0.965
BRCA1	P38398-1.2	Q563H	Pathogenic	0.773
BRCA1	P38398-1.2	Q563I	Pathogenic	0.918
BRCA1	P38398-1.2	Q563K	Pathogenic	0.774
BRCA1	P38398-1.2	Q563L	Pathogenic	0.886
BRCA1	P38398-1.2	Q563M	Pathogenic	0.792
BRCA1	P38398-1.2	Q563N	Pathogenic	0.823
BRCA1	P38398-1.2	Q563P	Pathogenic	0.883
BRCA1	P38398-1.2	Q563R	Pathogenic	0.82
BRCA1	P38398-1.2	Q563S	Pathogenic	0.886
BRCA1	P38398-1.2	Q563T	Pathogenic	0.877
BRCA1	P38398-1.2	Q563V	Pathogenic	0.885
BRCA1	P38398-1.2	Q563W	Pathogenic	0.948
BRCA1	P38398-1.2	Q563Y	Pathogenic	0.889
BRCA1	P38398-1.2	N564A	Neutral	0.061
BRCA1	P38398-1.2	N564C	Neutral	0.057
BRCA1	P38398-1.2	N564D	Neutral	0.013
BRCA1	P38398-1.2	N564E	Neutral	0.022
BRCA1	P38398-1.2	N564F	Neutral	0.102
BRCA1	P38398-1.2	N564G	Neutral	0.046
BRCA1	P38398-1.2	N564H	Neutral	0.018
BRCA1	P38398-1.2	N564I	Neutral	0.081
BRCA1	P38398-1.2	N564K	Neutral	0.038
BRCA1	P38398-1.2	N564L	Neutral	0.082
BRCA1	P38398-1.2	N564M	Neutral	0.059
BRCA1	P38398-1.2	N564P	Neutral	0.037
BRCA1	P38398-1.2	N564Q	Neutral	0.024
BRCA1	P38398-1.2	N564R	Neutral	0.05
BRCA1	P38398-1.2	N564S	Neutral	0.019
BRCA1	P38398-1.2	N564T	Neutral	0.017
BRCA1	P38398-1.2	N564V	Neutral	0.056
BRCA1	P38398-1.2	N564W	Neutral	0.231
BRCA1	P38398-1.2	N564Y	Neutral	0.084
BRCA1	P38398-1.2	E565A	Pathogenic	0.64
BRCA1	P38398-1.2	E565C	Pathogenic	0.774
BRCA1	P38398-1.2	E565D	Neutral	0.262
BRCA1	P38398-1.2	E565F	Pathogenic	0.715
BRCA1	P38398-1.2	E565G	Pathogenic	0.797
BRCA1	P38398-1.2	E565H	Neutral	0.373
BRCA1	P38398-1.2	E565I	Pathogenic	0.662
BRCA1	P38398-1.2	E565K	Neutral	0.378
BRCA1	P38398-1.2	E565L	Pathogenic	0.663
BRCA1	P38398-1.2	E565M	Pathogenic	0.579
BRCA1	P38398-1.2	E565N	Neutral	0.397
BRCA1	P38398-1.2	E565P	Pathogenic	0.514
BRCA1	P38398-1.2	E565Q	Neutral	0.209
BRCA1	P38398-1.2	E565R	Pathogenic	0.539
BRCA1	P38398-1.2	E565S	Pathogenic	0.521
BRCA1	P38398-1.2	E565T	Neutral	0.499
BRCA1	P38398-1.2	E565V	Pathogenic	0.519
BRCA1	P38398-1.2	E565W	Pathogenic	0.822
BRCA1	P38398-1.2	E565Y	Pathogenic	0.669
BRCA1	P38398-1.2	K566A	Neutral	0.275
BRCA1	P38398-1.2	K566C	Neutral	0.337
BRCA1	P38398-1.2	K566D	Neutral	0.185
BRCA1	P38398-1.2	K566E	Neutral	0.068
BRCA1	P38398-1.2	K566F	Neutral	0.144
BRCA1	P38398-1.2	K566G	Neutral	0.456
BRCA1	P38398-1.2	K566H	Neutral	0.109
BRCA1	P38398-1.2	K566I	Neutral	0.177
BRCA1	P38398-1.2	K566L	Neutral	0.13
BRCA1	P38398-1.2	K566M	Neutral	0.095
BRCA1	P38398-1.2	K566N	Neutral	0.123
BRCA1	P38398-1.2	K566P	Neutral	0.184
BRCA1	P38398-1.2	K566Q	Neutral	0.061
BRCA1	P38398-1.2	K566R	Neutral	0.037
BRCA1	P38398-1.2	K566S	Neutral	0.188
BRCA1	P38398-1.2	K566T	Neutral	0.176
BRCA1	P38398-1.2	K566V	Neutral	0.187
BRCA1	P38398-1.2	K566W	Neutral	0.237
BRCA1	P38398-1.2	K566Y	Neutral	0.12
BRCA1	P38398-1.2	N567A	Pathogenic	0.566
BRCA1	P38398-1.2	N567C	Pathogenic	0.548
BRCA1	P38398-1.2	N567D	Neutral	0.207
BRCA1	P38398-1.2	N567E	Neutral	0.31
BRCA1	P38398-1.2	N567F	Pathogenic	0.695
BRCA1	P38398-1.2	N567G	Neutral	0.491
BRCA1	P38398-1.2	N567H	Neutral	0.273
BRCA1	P38398-1.2	N567I	Pathogenic	0.641
BRCA1	P38398-1.2	N567K	Neutral	0.443
BRCA1	P38398-1.2	N567L	Pathogenic	0.641
BRCA1	P38398-1.2	N567M	Pathogenic	0.556
BRCA1	P38398-1.2	N567P	Neutral	0.437
BRCA1	P38398-1.2	N567Q	Neutral	0.332
BRCA1	P38398-1.2	N567R	Pathogenic	0.514
BRCA1	P38398-1.2	N567S	Neutral	0.278
BRCA1	P38398-1.2	N567T	Neutral	0.261
BRCA1	P38398-1.2	N567V	Pathogenic	0.542
BRCA1	P38398-1.2	N567W	Pathogenic	0.858
BRCA1	P38398-1.2	N567Y	Pathogenic	0.647
BRCA1	P38398-1.2	P568A	Neutral	0.034
BRCA1	P38398-1.2	P568C	Neutral	0.046
BRCA1	P38398-1.2	P568D	Neutral	0.021
BRCA1	P38398-1.2	P568E	Neutral	0.031
BRCA1	P38398-1.2	P568F	Neutral	0.144
BRCA1	P38398-1.2	P568G	Neutral	0.071
BRCA1	P38398-1.2	P568H	Neutral	0.053
BRCA1	P38398-1.2	P568I	Neutral	0.084
BRCA1	P38398-1.2	P568K	Neutral	0.053
BRCA1	P38398-1.2	P568L	Neutral	0.084
BRCA1	P38398-1.2	P568M	Neutral	0.061
BRCA1	P38398-1.2	P568N	Neutral	0.033
BRCA1	P38398-1.2	P568Q	Neutral	0.034
BRCA1	P38398-1.2	P568R	Neutral	0.097
BRCA1	P38398-1.2	P568S	Neutral	0.03
BRCA1	P38398-1.2	P568T	Neutral	0.022
BRCA1	P38398-1.2	P568V	Neutral	0.041
BRCA1	P38398-1.2	P568W	Neutral	0.238
BRCA1	P38398-1.2	P568Y	Neutral	0.12
BRCA1	P38398-1.2	N569A	Neutral	0.25
BRCA1	P38398-1.2	N569C	Neutral	0.237
BRCA1	P38398-1.2	N569D	Neutral	0.063
BRCA1	P38398-1.2	N569E	Neutral	0.103
BRCA1	P38398-1.2	N569F	Neutral	0.368
BRCA1	P38398-1.2	N569G	Neutral	0.198
BRCA1	P38398-1.2	N569H	Neutral	0.088
BRCA1	P38398-1.2	N569I	Neutral	0.314
BRCA1	P38398-1.2	N569K	Neutral	0.169
BRCA1	P38398-1.2	N569L	Neutral	0.314
BRCA1	P38398-1.2	N569M	Neutral	0.243
BRCA1	P38398-1.2	N569P	Neutral	0.166
BRCA1	P38398-1.2	N569Q	Neutral	0.113
BRCA1	P38398-1.2	N569R	Neutral	0.213
BRCA1	P38398-1.2	N569S	Neutral	0.09
BRCA1	P38398-1.2	N569T	Neutral	0.083
BRCA1	P38398-1.2	N569V	Neutral	0.232
BRCA1	P38398-1.2	N569W	Pathogenic	0.608
BRCA1	P38398-1.2	N569Y	Neutral	0.32
BRCA1	P38398-1.2	P570A	Neutral	0.451
BRCA1	P38398-1.2	P570C	Pathogenic	0.528
BRCA1	P38398-1.2	P570D	Neutral	0.331
BRCA1	P38398-1.2	P570E	Neutral	0.425
BRCA1	P38398-1.2	P570F	Pathogenic	0.798
BRCA1	P38398-1.2	P570G	Pathogenic	0.642
BRCA1	P38398-1.2	P570H	Pathogenic	0.568
BRCA1	P38398-1.2	P570I	Pathogenic	0.682
BRCA1	P38398-1.2	P570K	Pathogenic	0.566
BRCA1	P38398-1.2	P570L	Pathogenic	0.682
BRCA1	P38398-1.2	P570M	Pathogenic	0.601
BRCA1	P38398-1.2	P570N	Neutral	0.443
BRCA1	P38398-1.2	P570Q	Neutral	0.454
BRCA1	P38398-1.2	P570R	Pathogenic	0.715
BRCA1	P38398-1.2	P570S	Neutral	0.417
BRCA1	P38398-1.2	P570T	Neutral	0.345
BRCA1	P38398-1.2	P570V	Neutral	0.497
BRCA1	P38398-1.2	P570W	Pathogenic	0.879
BRCA1	P38398-1.2	P570Y	Pathogenic	0.761
BRCA1	P38398-1.2	I571A	Neutral	0.015
BRCA1	P38398-1.2	I571C	Neutral	0.01
BRCA1	P38398-1.2	I571D	Neutral	0.018
BRCA1	P38398-1.2	I571E	Neutral	0.012
BRCA1	P38398-1.2	I571F	Neutral	0.004
BRCA1	P38398-1.2	I571G	Neutral	0.066
BRCA1	P38398-1.2	I571H	Neutral	0.01
BRCA1	P38398-1.2	I571K	Neutral	0.011
BRCA1	P38398-1.2	I571L	Neutral	0.002
BRCA1	P38398-1.2	I571M	Neutral	0.002
BRCA1	P38398-1.2	I571N	Neutral	0.016
BRCA1	P38398-1.2	I571P	Neutral	0.019
BRCA1	P38398-1.2	I571Q	Neutral	0.011
BRCA1	P38398-1.2	I571R	Neutral	0.015
BRCA1	P38398-1.2	I571S	Neutral	0.019
BRCA1	P38398-1.2	I571T	Neutral	0.009
BRCA1	P38398-1.2	I571V	Neutral	0.002
BRCA1	P38398-1.2	I571W	Neutral	0.022
BRCA1	P38398-1.2	I571Y	Neutral	0.006
BRCA1	P38398-1.2	E572A	Neutral	0.352
BRCA1	P38398-1.2	E572C	Pathogenic	0.511
BRCA1	P38398-1.2	E572D	Neutral	0.098
BRCA1	P38398-1.2	E572F	Neutral	0.433
BRCA1	P38398-1.2	E572G	Pathogenic	0.545
BRCA1	P38398-1.2	E572H	Neutral	0.154
BRCA1	P38398-1.2	E572I	Neutral	0.375
BRCA1	P38398-1.2	E572K	Neutral	0.157
BRCA1	P38398-1.2	E572L	Neutral	0.375
BRCA1	P38398-1.2	E572M	Neutral	0.296
BRCA1	P38398-1.2	E572N	Neutral	0.168
BRCA1	P38398-1.2	E572P	Neutral	0.244
BRCA1	P38398-1.2	E572Q	Neutral	0.075
BRCA1	P38398-1.2	E572R	Neutral	0.263
BRCA1	P38398-1.2	E572S	Neutral	0.249
BRCA1	P38398-1.2	E572T	Neutral	0.234
BRCA1	P38398-1.2	E572V	Neutral	0.248
BRCA1	P38398-1.2	E572W	Pathogenic	0.585
BRCA1	P38398-1.2	E572Y	Neutral	0.382
BRCA1	P38398-1.2	S573A	Pathogenic	0.773
BRCA1	P38398-1.2	S573C	Pathogenic	0.89
BRCA1	P38398-1.2	S573D	Pathogenic	0.864
BRCA1	P38398-1.2	S573E	Pathogenic	0.905
BRCA1	P38398-1.2	S573F	Pathogenic	0.972
BRCA1	P38398-1.2	S573G	Pathogenic	0.882
BRCA1	P38398-1.2	S573H	Pathogenic	0.944
BRCA1	P38398-1.2	S573I	Pathogenic	0.964
BRCA1	P38398-1.2	S573K	Pathogenic	0.944
BRCA1	P38398-1.2	S573L	Pathogenic	0.964
BRCA1	P38398-1.2	S573M	Pathogenic	0.949
BRCA1	P38398-1.2	S573N	Pathogenic	0.832
BRCA1	P38398-1.2	S573P	Pathogenic	0.899
BRCA1	P38398-1.2	S573Q	Pathogenic	0.914
BRCA1	P38398-1.2	S573R	Pathogenic	0.97
BRCA1	P38398-1.2	S573T	Pathogenic	0.823
BRCA1	P38398-1.2	S573V	Pathogenic	0.947
BRCA1	P38398-1.2	S573W	Pathogenic	0.989
BRCA1	P38398-1.2	S573Y	Pathogenic	0.975
BRCA1	P38398-1.2	L574A	Pathogenic	0.973
BRCA1	P38398-1.2	L574C	Pathogenic	0.96
BRCA1	P38398-1.2	L574D	Pathogenic	0.984
BRCA1	P38398-1.2	L574E	Pathogenic	0.966
BRCA1	P38398-1.2	L574F	Pathogenic	0.902
BRCA1	P38398-1.2	L574G	Pathogenic	0.994
BRCA1	P38398-1.2	L574H	Pathogenic	0.96
BRCA1	P38398-1.2	L574I	Pathogenic	0.776
BRCA1	P38398-1.2	L574K	Pathogenic	0.947
BRCA1	P38398-1.2	L574M	Pathogenic	0.775
BRCA1	P38398-1.2	L574N	Pathogenic	0.974
BRCA1	P38398-1.2	L574P	Pathogenic	0.978
BRCA1	P38398-1.2	L574Q	Pathogenic	0.947
BRCA1	P38398-1.2	L574R	Pathogenic	0.96
BRCA1	P38398-1.2	L574S	Pathogenic	0.978
BRCA1	P38398-1.2	L574T	Pathogenic	0.952
BRCA1	P38398-1.2	L574V	Pathogenic	0.883
BRCA1	P38398-1.2	L574W	Pathogenic	0.972
BRCA1	P38398-1.2	L574Y	Pathogenic	0.937
BRCA1	P38398-1.2	E575A	Neutral	0.426
BRCA1	P38398-1.2	E575C	Pathogenic	0.589
BRCA1	P38398-1.2	E575D	Neutral	0.129
BRCA1	P38398-1.2	E575F	Pathogenic	0.512
BRCA1	P38398-1.2	E575G	Pathogenic	0.621
BRCA1	P38398-1.2	E575H	Neutral	0.199
BRCA1	P38398-1.2	E575I	Neutral	0.451
BRCA1	P38398-1.2	E575K	Neutral	0.203
BRCA1	P38398-1.2	E575L	Neutral	0.451
BRCA1	P38398-1.2	E575M	Neutral	0.366
BRCA1	P38398-1.2	E575N	Neutral	0.216
BRCA1	P38398-1.2	E575P	Neutral	0.307
BRCA1	P38398-1.2	E575Q	Neutral	0.1
BRCA1	P38398-1.2	E575R	Neutral	0.328
BRCA1	P38398-1.2	E575S	Neutral	0.313
BRCA1	P38398-1.2	E575T	Neutral	0.295
BRCA1	P38398-1.2	E575V	Neutral	0.311
BRCA1	P38398-1.2	E575W	Pathogenic	0.659
BRCA1	P38398-1.2	E575Y	Neutral	0.458
BRCA1	P38398-1.2	K576A	Pathogenic	0.863
BRCA1	P38398-1.2	K576C	Pathogenic	0.894
BRCA1	P38398-1.2	K576D	Pathogenic	0.79
BRCA1	P38398-1.2	K576E	Pathogenic	0.548
BRCA1	P38398-1.2	K576F	Pathogenic	0.736
BRCA1	P38398-1.2	K576G	Pathogenic	0.933
BRCA1	P38398-1.2	K576H	Pathogenic	0.67
BRCA1	P38398-1.2	K576I	Pathogenic	0.781
BRCA1	P38398-1.2	K576L	Pathogenic	0.712
BRCA1	P38398-1.2	K576M	Pathogenic	0.635
BRCA1	P38398-1.2	K576N	Pathogenic	0.7
BRCA1	P38398-1.2	K576P	Pathogenic	0.789
BRCA1	P38398-1.2	K576Q	Pathogenic	0.519
BRCA1	P38398-1.2	K576R	Neutral	0.389
BRCA1	P38398-1.2	K576S	Pathogenic	0.793
BRCA1	P38398-1.2	K576T	Pathogenic	0.779
BRCA1	P38398-1.2	K576V	Pathogenic	0.792
BRCA1	P38398-1.2	K576W	Pathogenic	0.837
BRCA1	P38398-1.2	K576Y	Pathogenic	0.692
BRCA1	P38398-1.2	E577A	Pathogenic	0.975
BRCA1	P38398-1.2	E577C	Pathogenic	0.987
BRCA1	P38398-1.2	E577D	Pathogenic	0.885
BRCA1	P38398-1.2	E577F	Pathogenic	0.982
BRCA1	P38398-1.2	E577G	Pathogenic	0.988
BRCA1	P38398-1.2	E577H	Pathogenic	0.928
BRCA1	P38398-1.2	E577I	Pathogenic	0.977
BRCA1	P38398-1.2	E577K	Pathogenic	0.93
BRCA1	P38398-1.2	E577L	Pathogenic	0.977
BRCA1	P38398-1.2	E577M	Pathogenic	0.968
BRCA1	P38398-1.2	E577N	Pathogenic	0.935
BRCA1	P38398-1.2	E577P	Pathogenic	0.958
BRCA1	P38398-1.2	E577Q	Pathogenic	0.852
BRCA1	P38398-1.2	E577R	Pathogenic	0.962
BRCA1	P38398-1.2	E577S	Pathogenic	0.959
BRCA1	P38398-1.2	E577T	Pathogenic	0.956
BRCA1	P38398-1.2	E577V	Pathogenic	0.959
BRCA1	P38398-1.2	E577W	Pathogenic	0.99
BRCA1	P38398-1.2	E577Y	Pathogenic	0.978
BRCA1	P38398-1.2	S578A	Pathogenic	0.743
BRCA1	P38398-1.2	S578C	Pathogenic	0.874
BRCA1	P38398-1.2	S578D	Pathogenic	0.844
BRCA1	P38398-1.2	S578E	Pathogenic	0.89
BRCA1	P38398-1.2	S578F	Pathogenic	0.967
BRCA1	P38398-1.2	S578G	Pathogenic	0.865
BRCA1	P38398-1.2	S578H	Pathogenic	0.935
BRCA1	P38398-1.2	S578I	Pathogenic	0.958
BRCA1	P38398-1.2	S578K	Pathogenic	0.935
BRCA1	P38398-1.2	S578L	Pathogenic	0.958
BRCA1	P38398-1.2	S578M	Pathogenic	0.941
BRCA1	P38398-1.2	S578N	Pathogenic	0.808
BRCA1	P38398-1.2	S578P	Pathogenic	0.884
BRCA1	P38398-1.2	S578Q	Pathogenic	0.901
BRCA1	P38398-1.2	S578R	Pathogenic	0.965
BRCA1	P38398-1.2	S578T	Pathogenic	0.798
BRCA1	P38398-1.2	S578V	Pathogenic	0.938
BRCA1	P38398-1.2	S578W	Pathogenic	0.987
BRCA1	P38398-1.2	S578Y	Pathogenic	0.971
BRCA1	P38398-1.2	A579C	Neutral	0.279
BRCA1	P38398-1.2	A579D	Neutral	0.471
BRCA1	P38398-1.2	A579E	Neutral	0.48
BRCA1	P38398-1.2	A579F	Pathogenic	0.701
BRCA1	P38398-1.2	A579G	Neutral	0.28
BRCA1	P38398-1.2	A579H	Pathogenic	0.622
BRCA1	P38398-1.2	A579I	Pathogenic	0.56
BRCA1	P38398-1.2	A579K	Pathogenic	0.62
BRCA1	P38398-1.2	A579L	Pathogenic	0.561
BRCA1	P38398-1.2	A579M	Pathogenic	0.563
BRCA1	P38398-1.2	A579N	Neutral	0.499
BRCA1	P38398-1.2	A579P	Neutral	0.38
BRCA1	P38398-1.2	A579Q	Pathogenic	0.51
BRCA1	P38398-1.2	A579R	Pathogenic	0.686
BRCA1	P38398-1.2	A579S	Neutral	0.169
BRCA1	P38398-1.2	A579T	Neutral	0.314
BRCA1	P38398-1.2	A579V	Neutral	0.37
BRCA1	P38398-1.2	A579W	Pathogenic	0.862
BRCA1	P38398-1.2	A579Y	Pathogenic	0.731
BRCA1	P38398-1.2	F580A	Pathogenic	0.726
BRCA1	P38398-1.2	F580C	Pathogenic	0.638
BRCA1	P38398-1.2	F580D	Pathogenic	0.687
BRCA1	P38398-1.2	F580E	Pathogenic	0.596
BRCA1	P38398-1.2	F580G	Pathogenic	0.853
BRCA1	P38398-1.2	F580H	Neutral	0.372
BRCA1	P38398-1.2	F580I	Neutral	0.271
BRCA1	P38398-1.2	F580K	Neutral	0.451
BRCA1	P38398-1.2	F580L	Neutral	0.271
BRCA1	P38398-1.2	F580M	Neutral	0.269
BRCA1	P38398-1.2	F580N	Pathogenic	0.664
BRCA1	P38398-1.2	F580P	Pathogenic	0.769
BRCA1	P38398-1.2	F580Q	Pathogenic	0.571
BRCA1	P38398-1.2	F580R	Pathogenic	0.523
BRCA1	P38398-1.2	F580S	Pathogenic	0.698
BRCA1	P38398-1.2	F580T	Pathogenic	0.598
BRCA1	P38398-1.2	F580V	Neutral	0.447
BRCA1	P38398-1.2	F580W	Neutral	0.272
BRCA1	P38398-1.2	F580Y	Neutral	0.099
BRCA1	P38398-1.2	K581A	Neutral	0.114
BRCA1	P38398-1.2	K581C	Neutral	0.148
BRCA1	P38398-1.2	K581D	Neutral	0.072
BRCA1	P38398-1.2	K581E	Neutral	0.024
BRCA1	P38398-1.2	K581F	Neutral	0.054
BRCA1	P38398-1.2	K581G	Neutral	0.222
BRCA1	P38398-1.2	K581H	Neutral	0.04
BRCA1	P38398-1.2	K581I	Neutral	0.068
BRCA1	P38398-1.2	K581L	Neutral	0.049
BRCA1	P38398-1.2	K581M	Neutral	0.035
BRCA1	P38398-1.2	K581N	Neutral	0.046
BRCA1	P38398-1.2	K581P	Neutral	0.071
BRCA1	P38398-1.2	K581Q	Neutral	0.022
BRCA1	P38398-1.2	K581R	Neutral	0.013
BRCA1	P38398-1.2	K581S	Neutral	0.073
BRCA1	P38398-1.2	K581T	Neutral	0.068
BRCA1	P38398-1.2	K581V	Neutral	0.073
BRCA1	P38398-1.2	K581W	Neutral	0.096
BRCA1	P38398-1.2	K581Y	Neutral	0.044
BRCA1	P38398-1.2	T582A	Neutral	0.201
BRCA1	P38398-1.2	T582C	Neutral	0.19
BRCA1	P38398-1.2	T582D	Neutral	0.173
BRCA1	P38398-1.2	T582E	Neutral	0.222
BRCA1	P38398-1.2	T582F	Neutral	0.42
BRCA1	P38398-1.2	T582G	Neutral	0.442
BRCA1	P38398-1.2	T582H	Neutral	0.338
BRCA1	P38398-1.2	T582I	Neutral	0.283
BRCA1	P38398-1.2	T582K	Neutral	0.336
BRCA1	P38398-1.2	T582L	Neutral	0.283
BRCA1	P38398-1.2	T582M	Neutral	0.285
BRCA1	P38398-1.2	T582N	Neutral	0.13
BRCA1	P38398-1.2	T582P	Neutral	0.178
BRCA1	P38398-1.2	T582Q	Neutral	0.244
BRCA1	P38398-1.2	T582R	Neutral	0.403
BRCA1	P38398-1.2	T582S	Neutral	0.132
BRCA1	P38398-1.2	T582V	Neutral	0.154
BRCA1	P38398-1.2	T582W	Pathogenic	0.572
BRCA1	P38398-1.2	T582Y	Neutral	0.457
BRCA1	P38398-1.2	K583A	Neutral	0.366
BRCA1	P38398-1.2	K583C	Neutral	0.436
BRCA1	P38398-1.2	K583D	Neutral	0.257
BRCA1	P38398-1.2	K583E	Neutral	0.1
BRCA1	P38398-1.2	K583F	Neutral	0.204
BRCA1	P38398-1.2	K583G	Pathogenic	0.56
BRCA1	P38398-1.2	K583H	Neutral	0.157
BRCA1	P38398-1.2	K583I	Neutral	0.247
BRCA1	P38398-1.2	K583L	Neutral	0.186
BRCA1	P38398-1.2	K583M	Neutral	0.138
BRCA1	P38398-1.2	K583N	Neutral	0.176
BRCA1	P38398-1.2	K583P	Neutral	0.256
BRCA1	P38398-1.2	K583Q	Neutral	0.09
BRCA1	P38398-1.2	K583R	Neutral	0.055
BRCA1	P38398-1.2	K583S	Neutral	0.261
BRCA1	P38398-1.2	K583T	Neutral	0.245
BRCA1	P38398-1.2	K583V	Neutral	0.26
BRCA1	P38398-1.2	K583W	Neutral	0.321
BRCA1	P38398-1.2	K583Y	Neutral	0.171
BRCA1	P38398-1.2	A584C	Neutral	0.324
BRCA1	P38398-1.2	A584D	Pathogenic	0.524
BRCA1	P38398-1.2	A584E	Pathogenic	0.534
BRCA1	P38398-1.2	A584F	Pathogenic	0.744
BRCA1	P38398-1.2	A584G	Neutral	0.326
BRCA1	P38398-1.2	A584H	Pathogenic	0.671
BRCA1	P38398-1.2	A584I	Pathogenic	0.613
BRCA1	P38398-1.2	A584K	Pathogenic	0.67
BRCA1	P38398-1.2	A584L	Pathogenic	0.613
BRCA1	P38398-1.2	A584M	Pathogenic	0.615
BRCA1	P38398-1.2	A584N	Pathogenic	0.553
BRCA1	P38398-1.2	A584P	Neutral	0.431
BRCA1	P38398-1.2	A584Q	Pathogenic	0.563
BRCA1	P38398-1.2	A584R	Pathogenic	0.73
BRCA1	P38398-1.2	A584S	Neutral	0.201
BRCA1	P38398-1.2	A584T	Neutral	0.362
BRCA1	P38398-1.2	A584V	Neutral	0.421
BRCA1	P38398-1.2	A584W	Pathogenic	0.885
BRCA1	P38398-1.2	A584Y	Pathogenic	0.771
BRCA1	P38398-1.2	E585A	Pathogenic	0.799
BRCA1	P38398-1.2	E585C	Pathogenic	0.885
BRCA1	P38398-1.2	E585D	Neutral	0.444
BRCA1	P38398-1.2	E585F	Pathogenic	0.849
BRCA1	P38398-1.2	E585G	Pathogenic	0.898
BRCA1	P38398-1.2	E585H	Pathogenic	0.572
BRCA1	P38398-1.2	E585I	Pathogenic	0.815
BRCA1	P38398-1.2	E585K	Pathogenic	0.577
BRCA1	P38398-1.2	E585L	Pathogenic	0.815
BRCA1	P38398-1.2	E585M	Pathogenic	0.756
BRCA1	P38398-1.2	E585N	Pathogenic	0.597
BRCA1	P38398-1.2	E585P	Pathogenic	0.704
BRCA1	P38398-1.2	E585Q	Neutral	0.373
BRCA1	P38398-1.2	E585R	Pathogenic	0.724
BRCA1	P38398-1.2	E585S	Pathogenic	0.709
BRCA1	P38398-1.2	E585T	Pathogenic	0.691
BRCA1	P38398-1.2	E585V	Pathogenic	0.708
BRCA1	P38398-1.2	E585W	Pathogenic	0.912
BRCA1	P38398-1.2	E585Y	Pathogenic	0.819
BRCA1	P38398-1.2	P586A	Pathogenic	0.625
BRCA1	P38398-1.2	P586C	Pathogenic	0.695
BRCA1	P38398-1.2	P586D	Pathogenic	0.501
BRCA1	P38398-1.2	P586E	Pathogenic	0.6
BRCA1	P38398-1.2	P586F	Pathogenic	0.889
BRCA1	P38398-1.2	P586G	Pathogenic	0.785
BRCA1	P38398-1.2	P586H	Pathogenic	0.728
BRCA1	P38398-1.2	P586I	Pathogenic	0.813
BRCA1	P38398-1.2	P586K	Pathogenic	0.726
BRCA1	P38398-1.2	P586L	Pathogenic	0.814
BRCA1	P38398-1.2	P586M	Pathogenic	0.754
BRCA1	P38398-1.2	P586N	Pathogenic	0.618
BRCA1	P38398-1.2	P586Q	Pathogenic	0.628
BRCA1	P38398-1.2	P586R	Pathogenic	0.836
BRCA1	P38398-1.2	P586S	Pathogenic	0.592
BRCA1	P38398-1.2	P586T	Pathogenic	0.517
BRCA1	P38398-1.2	P586V	Pathogenic	0.668
BRCA1	P38398-1.2	P586W	Pathogenic	0.937
BRCA1	P38398-1.2	P586Y	Pathogenic	0.866
BRCA1	P38398-1.2	I587A	Pathogenic	0.609
BRCA1	P38398-1.2	I587C	Pathogenic	0.508
BRCA1	P38398-1.2	I587D	Pathogenic	0.649
BRCA1	P38398-1.2	I587E	Pathogenic	0.554
BRCA1	P38398-1.2	I587F	Neutral	0.286
BRCA1	P38398-1.2	I587G	Pathogenic	0.875
BRCA1	P38398-1.2	I587H	Pathogenic	0.508
BRCA1	P38398-1.2	I587K	Pathogenic	0.531
BRCA1	P38398-1.2	I587L	Neutral	0.131
BRCA1	P38398-1.2	I587M	Neutral	0.177
BRCA1	P38398-1.2	I587N	Pathogenic	0.624
BRCA1	P38398-1.2	I587P	Pathogenic	0.661
BRCA1	P38398-1.2	I587Q	Pathogenic	0.529
BRCA1	P38398-1.2	I587R	Pathogenic	0.601
BRCA1	P38398-1.2	I587S	Pathogenic	0.66
BRCA1	P38398-1.2	I587T	Neutral	0.466
BRCA1	P38398-1.2	I587V	Neutral	0.137
BRCA1	P38398-1.2	I587W	Pathogenic	0.688
BRCA1	P38398-1.2	I587Y	Neutral	0.393
BRCA1	P38398-1.2	S588A	Neutral	0.261
BRCA1	P38398-1.2	S588C	Neutral	0.458
BRCA1	P38398-1.2	S588D	Neutral	0.398
BRCA1	P38398-1.2	S588E	Neutral	0.497
BRCA1	P38398-1.2	S588F	Pathogenic	0.781
BRCA1	P38398-1.2	S588G	Neutral	0.439
BRCA1	P38398-1.2	S588H	Pathogenic	0.636
BRCA1	P38398-1.2	S588I	Pathogenic	0.736
BRCA1	P38398-1.2	S588K	Pathogenic	0.636
BRCA1	P38398-1.2	S588L	Pathogenic	0.736
BRCA1	P38398-1.2	S588M	Pathogenic	0.662
BRCA1	P38398-1.2	S588N	Neutral	0.34
BRCA1	P38398-1.2	S588P	Neutral	0.482
BRCA1	P38398-1.2	S588Q	Pathogenic	0.527
BRCA1	P38398-1.2	S588R	Pathogenic	0.77
BRCA1	P38398-1.2	S588T	Neutral	0.326
BRCA1	P38398-1.2	S588V	Pathogenic	0.649
BRCA1	P38398-1.2	S588W	Pathogenic	0.904
BRCA1	P38398-1.2	S588Y	Pathogenic	0.805
BRCA1	P38398-1.2	S589A	Neutral	0.039
BRCA1	P38398-1.2	S589C	Neutral	0.088
BRCA1	P38398-1.2	S589D	Neutral	0.07
BRCA1	P38398-1.2	S589E	Neutral	0.101
BRCA1	P38398-1.2	S589F	Neutral	0.289
BRCA1	P38398-1.2	S589G	Neutral	0.082
BRCA1	P38398-1.2	S589H	Neutral	0.167
BRCA1	P38398-1.2	S589I	Neutral	0.242
BRCA1	P38398-1.2	S589K	Neutral	0.166
BRCA1	P38398-1.2	S589L	Neutral	0.242
BRCA1	P38398-1.2	S589M	Neutral	0.183
BRCA1	P38398-1.2	S589N	Neutral	0.056
BRCA1	P38398-1.2	S589P	Neutral	0.096
BRCA1	P38398-1.2	S589Q	Neutral	0.113
BRCA1	P38398-1.2	S589R	Neutral	0.277
BRCA1	P38398-1.2	S589T	Neutral	0.052
BRCA1	P38398-1.2	S589V	Neutral	0.174
BRCA1	P38398-1.2	S589W	Pathogenic	0.519
BRCA1	P38398-1.2	S589Y	Neutral	0.321
BRCA1	P38398-1.2	S590A	Pathogenic	0.672
BRCA1	P38398-1.2	S590C	Pathogenic	0.83
BRCA1	P38398-1.2	S590D	Pathogenic	0.792
BRCA1	P38398-1.2	S590E	Pathogenic	0.851
BRCA1	P38398-1.2	S590F	Pathogenic	0.954
BRCA1	P38398-1.2	S590G	Pathogenic	0.819
BRCA1	P38398-1.2	S590H	Pathogenic	0.91
BRCA1	P38398-1.2	S590I	Pathogenic	0.941
BRCA1	P38398-1.2	S590K	Pathogenic	0.91
BRCA1	P38398-1.2	S590L	Pathogenic	0.942
BRCA1	P38398-1.2	S590M	Pathogenic	0.919
BRCA1	P38398-1.2	S590N	Pathogenic	0.748
BRCA1	P38398-1.2	S590P	Pathogenic	0.843
BRCA1	P38398-1.2	S590Q	Pathogenic	0.865
BRCA1	P38398-1.2	S590R	Pathogenic	0.951
BRCA1	P38398-1.2	S590T	Pathogenic	0.736
BRCA1	P38398-1.2	S590V	Pathogenic	0.914
BRCA1	P38398-1.2	S590W	Pathogenic	0.982
BRCA1	P38398-1.2	S590Y	Pathogenic	0.96
BRCA1	P38398-1.2	I591A	Pathogenic	0.767
BRCA1	P38398-1.2	I591C	Pathogenic	0.687
BRCA1	P38398-1.2	I591D	Pathogenic	0.797
BRCA1	P38398-1.2	I591E	Pathogenic	0.725
BRCA1	P38398-1.2	I591F	Neutral	0.459
BRCA1	P38398-1.2	I591G	Pathogenic	0.937
BRCA1	P38398-1.2	I591H	Pathogenic	0.687
BRCA1	P38398-1.2	I591K	Pathogenic	0.706
BRCA1	P38398-1.2	I591L	Neutral	0.243
BRCA1	P38398-1.2	I591M	Neutral	0.314
BRCA1	P38398-1.2	I591N	Pathogenic	0.779
BRCA1	P38398-1.2	I591P	Pathogenic	0.805
BRCA1	P38398-1.2	I591Q	Pathogenic	0.704
BRCA1	P38398-1.2	I591R	Pathogenic	0.762
BRCA1	P38398-1.2	I591S	Pathogenic	0.805
BRCA1	P38398-1.2	I591T	Pathogenic	0.649
BRCA1	P38398-1.2	I591V	Neutral	0.252
BRCA1	P38398-1.2	I591W	Pathogenic	0.824
BRCA1	P38398-1.2	I591Y	Pathogenic	0.579
BRCA1	P38398-1.2	S592A	Neutral	0.154
BRCA1	P38398-1.2	S592C	Neutral	0.303
BRCA1	P38398-1.2	S592D	Neutral	0.254
BRCA1	P38398-1.2	S592E	Neutral	0.337
BRCA1	P38398-1.2	S592F	Pathogenic	0.647
BRCA1	P38398-1.2	S592G	Neutral	0.287
BRCA1	P38398-1.2	S592H	Neutral	0.474
BRCA1	P38398-1.2	S592I	Pathogenic	0.589
BRCA1	P38398-1.2	S592K	Neutral	0.473
BRCA1	P38398-1.2	S592L	Pathogenic	0.59
BRCA1	P38398-1.2	S592M	Pathogenic	0.502
BRCA1	P38398-1.2	S592N	Neutral	0.209
BRCA1	P38398-1.2	S592P	Neutral	0.323
BRCA1	P38398-1.2	S592Q	Neutral	0.364
BRCA1	P38398-1.2	S592R	Pathogenic	0.633
BRCA1	P38398-1.2	S592T	Neutral	0.199
BRCA1	P38398-1.2	S592V	Neutral	0.487
BRCA1	P38398-1.2	S592W	Pathogenic	0.829
BRCA1	P38398-1.2	S592Y	Pathogenic	0.68
BRCA1	P38398-1.2	N593A	Neutral	0.269
BRCA1	P38398-1.2	N593C	Neutral	0.256
BRCA1	P38398-1.2	N593D	Neutral	0.069
BRCA1	P38398-1.2	N593E	Neutral	0.113
BRCA1	P38398-1.2	N593F	Neutral	0.392
BRCA1	P38398-1.2	N593G	Neutral	0.215
BRCA1	P38398-1.2	N593H	Neutral	0.096
BRCA1	P38398-1.2	N593I	Neutral	0.335
BRCA1	P38398-1.2	N593K	Neutral	0.183
BRCA1	P38398-1.2	N593L	Neutral	0.336
BRCA1	P38398-1.2	N593M	Neutral	0.262
BRCA1	P38398-1.2	N593P	Neutral	0.18
BRCA1	P38398-1.2	N593Q	Neutral	0.123
BRCA1	P38398-1.2	N593R	Neutral	0.231
BRCA1	P38398-1.2	N593S	Neutral	0.098
BRCA1	P38398-1.2	N593T	Neutral	0.091
BRCA1	P38398-1.2	N593V	Neutral	0.251
BRCA1	P38398-1.2	N593W	Pathogenic	0.631
BRCA1	P38398-1.2	N593Y	Neutral	0.342
BRCA1	P38398-1.2	M594A	Neutral	0.382
BRCA1	P38398-1.2	M594C	Neutral	0.291
BRCA1	P38398-1.2	M594D	Neutral	0.424
BRCA1	P38398-1.2	M594E	Neutral	0.256
BRCA1	P38398-1.2	M594F	Neutral	0.135
BRCA1	P38398-1.2	M594G	Pathogenic	0.66
BRCA1	P38398-1.2	M594H	Neutral	0.222
BRCA1	P38398-1.2	M594I	Neutral	0.078
BRCA1	P38398-1.2	M594K	Neutral	0.179
BRCA1	P38398-1.2	M594L	Neutral	0.056
BRCA1	P38398-1.2	M594N	Neutral	0.315
BRCA1	P38398-1.2	M594P	Neutral	0.35
BRCA1	P38398-1.2	M594Q	Neutral	0.13
BRCA1	P38398-1.2	M594R	Neutral	0.225
BRCA1	P38398-1.2	M594S	Neutral	0.35
BRCA1	P38398-1.2	M594T	Neutral	0.258
BRCA1	P38398-1.2	M594V	Neutral	0.116
BRCA1	P38398-1.2	M594W	Neutral	0.293
BRCA1	P38398-1.2	M594Y	Neutral	0.205
BRCA1	P38398-1.2	E595A	Pathogenic	0.74
BRCA1	P38398-1.2	E595C	Pathogenic	0.846
BRCA1	P38398-1.2	E595D	Neutral	0.363
BRCA1	P38398-1.2	E595F	Pathogenic	0.8
BRCA1	P38398-1.2	E595G	Pathogenic	0.863
BRCA1	P38398-1.2	E595H	Neutral	0.488
BRCA1	P38398-1.2	E595I	Pathogenic	0.759
BRCA1	P38398-1.2	E595K	Neutral	0.493
BRCA1	P38398-1.2	E595L	Pathogenic	0.759
BRCA1	P38398-1.2	E595M	Pathogenic	0.688
BRCA1	P38398-1.2	E595N	Pathogenic	0.514
BRCA1	P38398-1.2	E595P	Pathogenic	0.629
BRCA1	P38398-1.2	E595Q	Neutral	0.298
BRCA1	P38398-1.2	E595R	Pathogenic	0.651
BRCA1	P38398-1.2	E595S	Pathogenic	0.635
BRCA1	P38398-1.2	E595T	Pathogenic	0.615
BRCA1	P38398-1.2	E595V	Pathogenic	0.634
BRCA1	P38398-1.2	E595W	Pathogenic	0.881
BRCA1	P38398-1.2	E595Y	Pathogenic	0.764
BRCA1	P38398-1.2	L596A	Pathogenic	0.877
BRCA1	P38398-1.2	L596C	Pathogenic	0.825
BRCA1	P38398-1.2	L596D	Pathogenic	0.924
BRCA1	P38398-1.2	L596E	Pathogenic	0.851
BRCA1	P38398-1.2	L596F	Pathogenic	0.646
BRCA1	P38398-1.2	L596G	Pathogenic	0.97
BRCA1	P38398-1.2	L596H	Pathogenic	0.825
BRCA1	P38398-1.2	L596I	Neutral	0.408
BRCA1	P38398-1.2	L596K	Pathogenic	0.782
BRCA1	P38398-1.2	L596M	Neutral	0.406
BRCA1	P38398-1.2	L596N	Pathogenic	0.884
BRCA1	P38398-1.2	L596P	Pathogenic	0.899
BRCA1	P38398-1.2	L596Q	Pathogenic	0.781
BRCA1	P38398-1.2	L596R	Pathogenic	0.827
BRCA1	P38398-1.2	L596S	Pathogenic	0.899
BRCA1	P38398-1.2	L596T	Pathogenic	0.8
BRCA1	P38398-1.2	L596V	Pathogenic	0.6
BRCA1	P38398-1.2	L596W	Pathogenic	0.875
BRCA1	P38398-1.2	L596Y	Pathogenic	0.748
BRCA1	P38398-1.2	E597A	Pathogenic	0.925
BRCA1	P38398-1.2	E597C	Pathogenic	0.96
BRCA1	P38398-1.2	E597D	Pathogenic	0.712
BRCA1	P38398-1.2	E597F	Pathogenic	0.946
BRCA1	P38398-1.2	E597G	Pathogenic	0.965
BRCA1	P38398-1.2	E597H	Pathogenic	0.805
BRCA1	P38398-1.2	E597I	Pathogenic	0.932
BRCA1	P38398-1.2	E597K	Pathogenic	0.809
BRCA1	P38398-1.2	E597L	Pathogenic	0.932
BRCA1	P38398-1.2	E597M	Pathogenic	0.906
BRCA1	P38398-1.2	E597N	Pathogenic	0.821
BRCA1	P38398-1.2	E597P	Pathogenic	0.88
BRCA1	P38398-1.2	E597Q	Pathogenic	0.648
BRCA1	P38398-1.2	E597R	Pathogenic	0.89
BRCA1	P38398-1.2	E597S	Pathogenic	0.883
BRCA1	P38398-1.2	E597T	Pathogenic	0.874
BRCA1	P38398-1.2	E597V	Pathogenic	0.882
BRCA1	P38398-1.2	E597W	Pathogenic	0.97
BRCA1	P38398-1.2	E597Y	Pathogenic	0.934
BRCA1	P38398-1.2	L598A	Pathogenic	0.751
BRCA1	P38398-1.2	L598C	Pathogenic	0.667
BRCA1	P38398-1.2	L598D	Pathogenic	0.838
BRCA1	P38398-1.2	L598E	Pathogenic	0.707
BRCA1	P38398-1.2	L598F	Neutral	0.436
BRCA1	P38398-1.2	L598G	Pathogenic	0.932
BRCA1	P38398-1.2	L598H	Pathogenic	0.667
BRCA1	P38398-1.2	L598I	Neutral	0.226
BRCA1	P38398-1.2	L598K	Pathogenic	0.603
BRCA1	P38398-1.2	L598M	Neutral	0.225
BRCA1	P38398-1.2	L598N	Pathogenic	0.763
BRCA1	P38398-1.2	L598P	Pathogenic	0.79
BRCA1	P38398-1.2	L598Q	Pathogenic	0.602
BRCA1	P38398-1.2	L598R	Pathogenic	0.67
BRCA1	P38398-1.2	L598S	Pathogenic	0.79
BRCA1	P38398-1.2	L598T	Pathogenic	0.628
BRCA1	P38398-1.2	L598V	Neutral	0.389
BRCA1	P38398-1.2	L598W	Pathogenic	0.747
BRCA1	P38398-1.2	L598Y	Pathogenic	0.556
BRCA1	P38398-1.2	N599A	Pathogenic	0.774
BRCA1	P38398-1.2	N599C	Pathogenic	0.761
BRCA1	P38398-1.2	N599D	Neutral	0.406
BRCA1	P38398-1.2	N599E	Pathogenic	0.541
BRCA1	P38398-1.2	N599F	Pathogenic	0.857
BRCA1	P38398-1.2	N599G	Pathogenic	0.717
BRCA1	P38398-1.2	N599H	Neutral	0.497
BRCA1	P38398-1.2	N599I	Pathogenic	0.824
BRCA1	P38398-1.2	N599K	Pathogenic	0.676
BRCA1	P38398-1.2	N599L	Pathogenic	0.824
BRCA1	P38398-1.2	N599M	Pathogenic	0.767
BRCA1	P38398-1.2	N599P	Pathogenic	0.671
BRCA1	P38398-1.2	N599Q	Pathogenic	0.567
BRCA1	P38398-1.2	N599R	Pathogenic	0.736
BRCA1	P38398-1.2	N599S	Pathogenic	0.503
BRCA1	P38398-1.2	N599T	Neutral	0.481
BRCA1	P38398-1.2	N599V	Pathogenic	0.756
BRCA1	P38398-1.2	N599W	Pathogenic	0.941
BRCA1	P38398-1.2	N599Y	Pathogenic	0.828
BRCA1	P38398-1.2	I600A	Neutral	0.01
BRCA1	P38398-1.2	I600C	Neutral	0.007
BRCA1	P38398-1.2	I600D	Neutral	0.012
BRCA1	P38398-1.2	I600E	Neutral	0.008
BRCA1	P38398-1.2	I600F	Neutral	0.003
BRCA1	P38398-1.2	I600G	Neutral	0.046
BRCA1	P38398-1.2	I600H	Neutral	0.007
BRCA1	P38398-1.2	I600K	Neutral	0.008
BRCA1	P38398-1.2	I600L	Neutral	0.001
BRCA1	P38398-1.2	I600M	Neutral	0.001
BRCA1	P38398-1.2	I600N	Neutral	0.011
BRCA1	P38398-1.2	I600P	Neutral	0.013
BRCA1	P38398-1.2	I600Q	Neutral	0.008
BRCA1	P38398-1.2	I600R	Neutral	0.01
BRCA1	P38398-1.2	I600S	Neutral	0.013
BRCA1	P38398-1.2	I600T	Neutral	0.006
BRCA1	P38398-1.2	I600V	Neutral	0.001
BRCA1	P38398-1.2	I600W	Neutral	0.015
BRCA1	P38398-1.2	I600Y	Neutral	0.004
BRCA1	P38398-1.2	H601A	Neutral	0.261
BRCA1	P38398-1.2	H601C	Neutral	0.247
BRCA1	P38398-1.2	H601D	Neutral	0.124
BRCA1	P38398-1.2	H601E	Neutral	0.062
BRCA1	P38398-1.2	H601F	Neutral	0.101
BRCA1	P38398-1.2	H601G	Neutral	0.35
BRCA1	P38398-1.2	H601I	Neutral	0.154
BRCA1	P38398-1.2	H601K	Neutral	0.102
BRCA1	P38398-1.2	H601L	Neutral	0.154
BRCA1	P38398-1.2	H601M	Neutral	0.113
BRCA1	P38398-1.2	H601N	Neutral	0.058
BRCA1	P38398-1.2	H601P	Neutral	0.173
BRCA1	P38398-1.2	H601Q	Neutral	0.056
BRCA1	P38398-1.2	H601R	Neutral	0.095
BRCA1	P38398-1.2	H601S	Neutral	0.177
BRCA1	P38398-1.2	H601T	Neutral	0.165
BRCA1	P38398-1.2	H601V	Neutral	0.176
BRCA1	P38398-1.2	H601W	Neutral	0.229
BRCA1	P38398-1.2	H601Y	Neutral	0.042
BRCA1	P38398-1.2	N602A	Neutral	0.008
BRCA1	P38398-1.2	N602C	Neutral	0.007
BRCA1	P38398-1.2	N602D	Neutral	0.002
BRCA1	P38398-1.2	N602E	Neutral	0.003
BRCA1	P38398-1.2	N602F	Neutral	0.014
BRCA1	P38398-1.2	N602G	Neutral	0.006
BRCA1	P38398-1.2	N602H	Neutral	0.002
BRCA1	P38398-1.2	N602I	Neutral	0.011
BRCA1	P38398-1.2	N602K	Neutral	0.005
BRCA1	P38398-1.2	N602L	Neutral	0.011
BRCA1	P38398-1.2	N602M	Neutral	0.008
BRCA1	P38398-1.2	N602P	Neutral	0.005
BRCA1	P38398-1.2	N602Q	Neutral	0.003
BRCA1	P38398-1.2	N602R	Neutral	0.006
BRCA1	P38398-1.2	N602S	Neutral	0.002
BRCA1	P38398-1.2	N602T	Neutral	0.002
BRCA1	P38398-1.2	N602V	Neutral	0.007
BRCA1	P38398-1.2	N602W	Neutral	0.036
BRCA1	P38398-1.2	N602Y	Neutral	0.011
BRCA1	P38398-1.2	S603A	Pathogenic	0.706
BRCA1	P38398-1.2	S603C	Pathogenic	0.851
BRCA1	P38398-1.2	S603D	Pathogenic	0.817
BRCA1	P38398-1.2	S603E	Pathogenic	0.87
BRCA1	P38398-1.2	S603F	Pathogenic	0.96
BRCA1	P38398-1.2	S603G	Pathogenic	0.841
BRCA1	P38398-1.2	S603H	Pathogenic	0.922
BRCA1	P38398-1.2	S603I	Pathogenic	0.95
BRCA1	P38398-1.2	S603K	Pathogenic	0.922
BRCA1	P38398-1.2	S603L	Pathogenic	0.95
BRCA1	P38398-1.2	S603M	Pathogenic	0.93
BRCA1	P38398-1.2	S603N	Pathogenic	0.777
BRCA1	P38398-1.2	S603P	Pathogenic	0.863
BRCA1	P38398-1.2	S603Q	Pathogenic	0.883
BRCA1	P38398-1.2	S603R	Pathogenic	0.958
BRCA1	P38398-1.2	S603T	Pathogenic	0.766
BRCA1	P38398-1.2	S603V	Pathogenic	0.926
BRCA1	P38398-1.2	S603W	Pathogenic	0.985
BRCA1	P38398-1.2	S603Y	Pathogenic	0.965
BRCA1	P38398-1.2	K604A	Pathogenic	0.754
BRCA1	P38398-1.2	K604C	Pathogenic	0.805
BRCA1	P38398-1.2	K604D	Pathogenic	0.648
BRCA1	P38398-1.2	K604E	Neutral	0.373
BRCA1	P38398-1.2	K604F	Pathogenic	0.577
BRCA1	P38398-1.2	K604G	Pathogenic	0.872
BRCA1	P38398-1.2	K604H	Neutral	0.498
BRCA1	P38398-1.2	K604I	Pathogenic	0.636
BRCA1	P38398-1.2	K604L	Pathogenic	0.548
BRCA1	P38398-1.2	K604M	Neutral	0.46
BRCA1	P38398-1.2	K604N	Pathogenic	0.533
BRCA1	P38398-1.2	K604P	Pathogenic	0.647
BRCA1	P38398-1.2	K604Q	Neutral	0.345
BRCA1	P38398-1.2	K604R	Neutral	0.238
BRCA1	P38398-1.2	K604S	Pathogenic	0.653
BRCA1	P38398-1.2	K604T	Pathogenic	0.633
BRCA1	P38398-1.2	K604V	Pathogenic	0.651
BRCA1	P38398-1.2	K604W	Pathogenic	0.716
BRCA1	P38398-1.2	K604Y	Pathogenic	0.524
BRCA1	P38398-1.2	A605C	Neutral	0.223
BRCA1	P38398-1.2	A605D	Neutral	0.398
BRCA1	P38398-1.2	A605E	Neutral	0.407
BRCA1	P38398-1.2	A605F	Pathogenic	0.635
BRCA1	P38398-1.2	A605G	Neutral	0.225
BRCA1	P38398-1.2	A605H	Pathogenic	0.551
BRCA1	P38398-1.2	A605I	Neutral	0.487
BRCA1	P38398-1.2	A605K	Pathogenic	0.549
BRCA1	P38398-1.2	A605L	Neutral	0.487
BRCA1	P38398-1.2	A605M	Neutral	0.489
BRCA1	P38398-1.2	A605N	Neutral	0.426
BRCA1	P38398-1.2	A605P	Neutral	0.313
BRCA1	P38398-1.2	A605Q	Neutral	0.436
BRCA1	P38398-1.2	A605R	Pathogenic	0.619
BRCA1	P38398-1.2	A605S	Neutral	0.131
BRCA1	P38398-1.2	A605T	Neutral	0.254
BRCA1	P38398-1.2	A605V	Neutral	0.304
BRCA1	P38398-1.2	A605W	Pathogenic	0.822
BRCA1	P38398-1.2	A605Y	Pathogenic	0.669
BRCA1	P38398-1.2	P606A	Pathogenic	0.581
BRCA1	P38398-1.2	P606C	Pathogenic	0.654
BRCA1	P38398-1.2	P606D	Neutral	0.455
BRCA1	P38398-1.2	P606E	Pathogenic	0.555
BRCA1	P38398-1.2	P606F	Pathogenic	0.869
BRCA1	P38398-1.2	P606G	Pathogenic	0.752
BRCA1	P38398-1.2	P606H	Pathogenic	0.69
BRCA1	P38398-1.2	P606I	Pathogenic	0.784
BRCA1	P38398-1.2	P606K	Pathogenic	0.688
BRCA1	P38398-1.2	P606L	Pathogenic	0.784
BRCA1	P38398-1.2	P606M	Pathogenic	0.718
BRCA1	P38398-1.2	P606N	Pathogenic	0.574
BRCA1	P38398-1.2	P606Q	Pathogenic	0.584
BRCA1	P38398-1.2	P606R	Pathogenic	0.809
BRCA1	P38398-1.2	P606S	Pathogenic	0.547
BRCA1	P38398-1.2	P606T	Neutral	0.471
BRCA1	P38398-1.2	P606V	Pathogenic	0.625
BRCA1	P38398-1.2	P606W	Pathogenic	0.925
BRCA1	P38398-1.2	P606Y	Pathogenic	0.843
BRCA1	P38398-1.2	K607A	Pathogenic	0.769
BRCA1	P38398-1.2	K607C	Pathogenic	0.817
BRCA1	P38398-1.2	K607D	Pathogenic	0.666
BRCA1	P38398-1.2	K607E	Neutral	0.391
BRCA1	P38398-1.2	K607F	Pathogenic	0.596
BRCA1	P38398-1.2	K607G	Pathogenic	0.88
BRCA1	P38398-1.2	K607H	Pathogenic	0.518
BRCA1	P38398-1.2	K607I	Pathogenic	0.654
BRCA1	P38398-1.2	K607L	Pathogenic	0.568
BRCA1	P38398-1.2	K607M	Neutral	0.479
BRCA1	P38398-1.2	K607N	Pathogenic	0.553
BRCA1	P38398-1.2	K607P	Pathogenic	0.664
BRCA1	P38398-1.2	K607Q	Neutral	0.364
BRCA1	P38398-1.2	K607R	Neutral	0.252
BRCA1	P38398-1.2	K607S	Pathogenic	0.671
BRCA1	P38398-1.2	K607T	Pathogenic	0.651
BRCA1	P38398-1.2	K607V	Pathogenic	0.669
BRCA1	P38398-1.2	K607W	Pathogenic	0.732
BRCA1	P38398-1.2	K607Y	Pathogenic	0.544
BRCA1	P38398-1.2	K608A	Pathogenic	0.923
BRCA1	P38398-1.2	K608C	Pathogenic	0.942
BRCA1	P38398-1.2	K608D	Pathogenic	0.878
BRCA1	P38398-1.2	K608E	Pathogenic	0.7
BRCA1	P38398-1.2	K608F	Pathogenic	0.843
BRCA1	P38398-1.2	K608G	Pathogenic	0.964
BRCA1	P38398-1.2	K608H	Pathogenic	0.796
BRCA1	P38398-1.2	K608I	Pathogenic	0.873
BRCA1	P38398-1.2	K608L	Pathogenic	0.827
BRCA1	P38398-1.2	K608M	Pathogenic	0.77
BRCA1	P38398-1.2	K608N	Pathogenic	0.818
BRCA1	P38398-1.2	K608P	Pathogenic	0.878
BRCA1	P38398-1.2	K608Q	Pathogenic	0.674
BRCA1	P38398-1.2	K608R	Pathogenic	0.55
BRCA1	P38398-1.2	K608S	Pathogenic	0.881
BRCA1	P38398-1.2	K608T	Pathogenic	0.871
BRCA1	P38398-1.2	K608V	Pathogenic	0.88
BRCA1	P38398-1.2	K608W	Pathogenic	0.908
BRCA1	P38398-1.2	K608Y	Pathogenic	0.812
BRCA1	P38398-1.2	N609A	Pathogenic	0.629
BRCA1	P38398-1.2	N609C	Pathogenic	0.612
BRCA1	P38398-1.2	N609D	Neutral	0.253
BRCA1	P38398-1.2	N609E	Neutral	0.368
BRCA1	P38398-1.2	N609F	Pathogenic	0.747
BRCA1	P38398-1.2	N609G	Pathogenic	0.556
BRCA1	P38398-1.2	N609H	Neutral	0.328
BRCA1	P38398-1.2	N609I	Pathogenic	0.698
BRCA1	P38398-1.2	N609K	Pathogenic	0.508
BRCA1	P38398-1.2	N609L	Pathogenic	0.699
BRCA1	P38398-1.2	N609M	Pathogenic	0.619
BRCA1	P38398-1.2	N609P	Pathogenic	0.502
BRCA1	P38398-1.2	N609Q	Neutral	0.393
BRCA1	P38398-1.2	N609R	Pathogenic	0.579
BRCA1	P38398-1.2	N609S	Neutral	0.334
BRCA1	P38398-1.2	N609T	Neutral	0.315
BRCA1	P38398-1.2	N609V	Pathogenic	0.606
BRCA1	P38398-1.2	N609W	Pathogenic	0.887
BRCA1	P38398-1.2	N609Y	Pathogenic	0.705
BRCA1	P38398-1.2	R610A	Pathogenic	0.983
BRCA1	P38398-1.2	R610C	Pathogenic	0.988
BRCA1	P38398-1.2	R610D	Pathogenic	0.981
BRCA1	P38398-1.2	R610E	Pathogenic	0.943
BRCA1	P38398-1.2	R610F	Pathogenic	0.963
BRCA1	P38398-1.2	R610G	Pathogenic	0.992
BRCA1	P38398-1.2	R610H	Pathogenic	0.93
BRCA1	P38398-1.2	R610I	Pathogenic	0.971
BRCA1	P38398-1.2	R610K	Pathogenic	0.818
BRCA1	P38398-1.2	R610L	Pathogenic	0.959
BRCA1	P38398-1.2	R610M	Pathogenic	0.943
BRCA1	P38398-1.2	R610N	Pathogenic	0.957
BRCA1	P38398-1.2	R610P	Pathogenic	0.981
BRCA1	P38398-1.2	R610Q	Pathogenic	0.911
BRCA1	P38398-1.2	R610S	Pathogenic	0.981
BRCA1	P38398-1.2	R610T	Pathogenic	0.971
BRCA1	P38398-1.2	R610V	Pathogenic	0.981
BRCA1	P38398-1.2	R610W	Pathogenic	0.965
BRCA1	P38398-1.2	R610Y	Pathogenic	0.942
BRCA1	P38398-1.2	L611A	Pathogenic	0.989
BRCA1	P38398-1.2	L611C	Pathogenic	0.984
BRCA1	P38398-1.2	L611D	Pathogenic	0.994
BRCA1	P38398-1.2	L611E	Pathogenic	0.986
BRCA1	P38398-1.2	L611F	Pathogenic	0.959
BRCA1	P38398-1.2	L611G	Pathogenic	0.998
BRCA1	P38398-1.2	L611H	Pathogenic	0.984
BRCA1	P38398-1.2	L611I	Pathogenic	0.898
BRCA1	P38398-1.2	L611K	Pathogenic	0.979
BRCA1	P38398-1.2	L611M	Pathogenic	0.897
BRCA1	P38398-1.2	L611N	Pathogenic	0.99
BRCA1	P38398-1.2	L611P	Pathogenic	0.991
BRCA1	P38398-1.2	L611Q	Pathogenic	0.979
BRCA1	P38398-1.2	L611R	Pathogenic	0.984
BRCA1	P38398-1.2	L611S	Pathogenic	0.991
BRCA1	P38398-1.2	L611T	Pathogenic	0.981
BRCA1	P38398-1.2	L611V	Pathogenic	0.951
BRCA1	P38398-1.2	L611W	Pathogenic	0.989
BRCA1	P38398-1.2	L611Y	Pathogenic	0.974
BRCA1	P38398-1.2	R612A	Pathogenic	0.922
BRCA1	P38398-1.2	R612C	Pathogenic	0.941
BRCA1	P38398-1.2	R612D	Pathogenic	0.911
BRCA1	P38398-1.2	R612E	Pathogenic	0.767
BRCA1	P38398-1.2	R612F	Pathogenic	0.84
BRCA1	P38398-1.2	R612G	Pathogenic	0.963
BRCA1	P38398-1.2	R612H	Pathogenic	0.727
BRCA1	P38398-1.2	R612I	Pathogenic	0.87
BRCA1	P38398-1.2	R612K	Neutral	0.474
BRCA1	P38398-1.2	R612L	Pathogenic	0.824
BRCA1	P38398-1.2	R612M	Pathogenic	0.766
BRCA1	P38398-1.2	R612N	Pathogenic	0.815
BRCA1	P38398-1.2	R612P	Pathogenic	0.91
BRCA1	P38398-1.2	R612Q	Pathogenic	0.67
BRCA1	P38398-1.2	R612S	Pathogenic	0.913
BRCA1	P38398-1.2	R612T	Pathogenic	0.869
BRCA1	P38398-1.2	R612V	Pathogenic	0.912
BRCA1	P38398-1.2	R612W	Pathogenic	0.845
BRCA1	P38398-1.2	R612Y	Pathogenic	0.765
BRCA1	P38398-1.2	R613A	Pathogenic	0.916
BRCA1	P38398-1.2	R613C	Pathogenic	0.936
BRCA1	P38398-1.2	R613D	Pathogenic	0.904
BRCA1	P38398-1.2	R613E	Pathogenic	0.753
BRCA1	P38398-1.2	R613F	Pathogenic	0.829
BRCA1	P38398-1.2	R613G	Pathogenic	0.96
BRCA1	P38398-1.2	R613H	Pathogenic	0.711
BRCA1	P38398-1.2	R613I	Pathogenic	0.861
BRCA1	P38398-1.2	R613K	Neutral	0.454
BRCA1	P38398-1.2	R613L	Pathogenic	0.812
BRCA1	P38398-1.2	R613M	Pathogenic	0.752
BRCA1	P38398-1.2	R613N	Pathogenic	0.803
BRCA1	P38398-1.2	R613P	Pathogenic	0.904
BRCA1	P38398-1.2	R613Q	Pathogenic	0.653
BRCA1	P38398-1.2	R613S	Pathogenic	0.906
BRCA1	P38398-1.2	R613T	Pathogenic	0.86
BRCA1	P38398-1.2	R613V	Pathogenic	0.905
BRCA1	P38398-1.2	R613W	Pathogenic	0.834
BRCA1	P38398-1.2	R613Y	Pathogenic	0.75
BRCA1	P38398-1.2	K614A	Pathogenic	0.838
BRCA1	P38398-1.2	K614C	Pathogenic	0.874
BRCA1	P38398-1.2	K614D	Pathogenic	0.756
BRCA1	P38398-1.2	K614E	Neutral	0.5
BRCA1	P38398-1.2	K614F	Pathogenic	0.697
BRCA1	P38398-1.2	K614G	Pathogenic	0.919
BRCA1	P38398-1.2	K614H	Pathogenic	0.625
BRCA1	P38398-1.2	K614I	Pathogenic	0.746
BRCA1	P38398-1.2	K614L	Pathogenic	0.671
BRCA1	P38398-1.2	K614M	Pathogenic	0.589
BRCA1	P38398-1.2	K614N	Pathogenic	0.657
BRCA1	P38398-1.2	K614P	Pathogenic	0.755
BRCA1	P38398-1.2	K614Q	Neutral	0.47
BRCA1	P38398-1.2	K614R	Neutral	0.344
BRCA1	P38398-1.2	K614S	Pathogenic	0.76
BRCA1	P38398-1.2	K614T	Pathogenic	0.744
BRCA1	P38398-1.2	K614V	Pathogenic	0.759
BRCA1	P38398-1.2	K614W	Pathogenic	0.809
BRCA1	P38398-1.2	K614Y	Pathogenic	0.649
BRCA1	P38398-1.2	S615A	Pathogenic	0.599
BRCA1	P38398-1.2	S615C	Pathogenic	0.781
BRCA1	P38398-1.2	S615D	Pathogenic	0.736
BRCA1	P38398-1.2	S615E	Pathogenic	0.806
BRCA1	P38398-1.2	S615F	Pathogenic	0.938
BRCA1	P38398-1.2	S615G	Pathogenic	0.767
BRCA1	P38398-1.2	S615H	Pathogenic	0.881
BRCA1	P38398-1.2	S615I	Pathogenic	0.922
BRCA1	P38398-1.2	S615K	Pathogenic	0.881
BRCA1	P38398-1.2	S615L	Pathogenic	0.922
BRCA1	P38398-1.2	S615M	Pathogenic	0.892
BRCA1	P38398-1.2	S615N	Pathogenic	0.685
BRCA1	P38398-1.2	S615P	Pathogenic	0.797
BRCA1	P38398-1.2	S615Q	Pathogenic	0.824
BRCA1	P38398-1.2	S615R	Pathogenic	0.934
BRCA1	P38398-1.2	S615T	Pathogenic	0.671
BRCA1	P38398-1.2	S615V	Pathogenic	0.886
BRCA1	P38398-1.2	S615W	Pathogenic	0.976
BRCA1	P38398-1.2	S615Y	Pathogenic	0.946
BRCA1	P38398-1.2	S616A	Pathogenic	0.547
BRCA1	P38398-1.2	S616C	Pathogenic	0.743
BRCA1	P38398-1.2	S616D	Pathogenic	0.693
BRCA1	P38398-1.2	S616E	Pathogenic	0.771
BRCA1	P38398-1.2	S616F	Pathogenic	0.924
BRCA1	P38398-1.2	S616G	Pathogenic	0.727
BRCA1	P38398-1.2	S616H	Pathogenic	0.857
BRCA1	P38398-1.2	S616I	Pathogenic	0.905
BRCA1	P38398-1.2	S616K	Pathogenic	0.856
BRCA1	P38398-1.2	S616L	Pathogenic	0.905
BRCA1	P38398-1.2	S616M	Pathogenic	0.87
BRCA1	P38398-1.2	S616N	Pathogenic	0.637
BRCA1	P38398-1.2	S616P	Pathogenic	0.76
BRCA1	P38398-1.2	S616Q	Pathogenic	0.791
BRCA1	P38398-1.2	S616R	Pathogenic	0.92
BRCA1	P38398-1.2	S616T	Pathogenic	0.623
BRCA1	P38398-1.2	S616V	Pathogenic	0.863
BRCA1	P38398-1.2	S616W	Pathogenic	0.97
BRCA1	P38398-1.2	S616Y	Pathogenic	0.934
BRCA1	P38398-1.2	T617A	Neutral	0.159
BRCA1	P38398-1.2	T617C	Neutral	0.15
BRCA1	P38398-1.2	T617D	Neutral	0.135
BRCA1	P38398-1.2	T617E	Neutral	0.176
BRCA1	P38398-1.2	T617F	Neutral	0.352
BRCA1	P38398-1.2	T617G	Neutral	0.373
BRCA1	P38398-1.2	T617H	Neutral	0.277
BRCA1	P38398-1.2	T617I	Neutral	0.228
BRCA1	P38398-1.2	T617K	Neutral	0.275
BRCA1	P38398-1.2	T617L	Neutral	0.228
BRCA1	P38398-1.2	T617M	Neutral	0.23
BRCA1	P38398-1.2	T617N	Neutral	0.1
BRCA1	P38398-1.2	T617P	Neutral	0.139
BRCA1	P38398-1.2	T617Q	Neutral	0.194
BRCA1	P38398-1.2	T617R	Neutral	0.336
BRCA1	P38398-1.2	T617S	Neutral	0.103
BRCA1	P38398-1.2	T617V	Neutral	0.12
BRCA1	P38398-1.2	T617W	Pathogenic	0.5
BRCA1	P38398-1.2	T617Y	Neutral	0.387
BRCA1	P38398-1.2	R618A	Pathogenic	0.944
BRCA1	P38398-1.2	R618C	Pathogenic	0.957
BRCA1	P38398-1.2	R618D	Pathogenic	0.935
BRCA1	P38398-1.2	R618E	Pathogenic	0.824
BRCA1	P38398-1.2	R618F	Pathogenic	0.882
BRCA1	P38398-1.2	R618G	Pathogenic	0.974
BRCA1	P38398-1.2	R618H	Pathogenic	0.791
BRCA1	P38398-1.2	R618I	Pathogenic	0.905
BRCA1	P38398-1.2	R618K	Pathogenic	0.561
BRCA1	P38398-1.2	R618L	Pathogenic	0.869
BRCA1	P38398-1.2	R618M	Pathogenic	0.823
BRCA1	P38398-1.2	R618N	Pathogenic	0.862
BRCA1	P38398-1.2	R618P	Pathogenic	0.935
BRCA1	P38398-1.2	R618Q	Pathogenic	0.743
BRCA1	P38398-1.2	R618S	Pathogenic	0.937
BRCA1	P38398-1.2	R618T	Pathogenic	0.904
BRCA1	P38398-1.2	R618V	Pathogenic	0.936
BRCA1	P38398-1.2	R618W	Pathogenic	0.886
BRCA1	P38398-1.2	R618Y	Pathogenic	0.822
BRCA1	P38398-1.2	H619A	Neutral	0.058
BRCA1	P38398-1.2	H619C	Neutral	0.054
BRCA1	P38398-1.2	H619D	Neutral	0.024
BRCA1	P38398-1.2	H619E	Neutral	0.011
BRCA1	P38398-1.2	H619F	Neutral	0.019
BRCA1	P38398-1.2	H619G	Neutral	0.086
BRCA1	P38398-1.2	H619I	Neutral	0.031
BRCA1	P38398-1.2	H619K	Neutral	0.019
BRCA1	P38398-1.2	H619L	Neutral	0.031
BRCA1	P38398-1.2	H619M	Neutral	0.022
BRCA1	P38398-1.2	H619N	Neutral	0.011
BRCA1	P38398-1.2	H619P	Neutral	0.035
BRCA1	P38398-1.2	H619Q	Neutral	0.01
BRCA1	P38398-1.2	H619R	Neutral	0.018
BRCA1	P38398-1.2	H619S	Neutral	0.036
BRCA1	P38398-1.2	H619T	Neutral	0.033
BRCA1	P38398-1.2	H619V	Neutral	0.036
BRCA1	P38398-1.2	H619W	Neutral	0.049
BRCA1	P38398-1.2	H619Y	Neutral	0.008
BRCA1	P38398-1.2	I620A	Neutral	0.225
BRCA1	P38398-1.2	I620C	Neutral	0.162
BRCA1	P38398-1.2	I620D	Neutral	0.257
BRCA1	P38398-1.2	I620E	Neutral	0.189
BRCA1	P38398-1.2	I620F	Neutral	0.07
BRCA1	P38398-1.2	I620G	Pathogenic	0.568
BRCA1	P38398-1.2	I620H	Neutral	0.162
BRCA1	P38398-1.2	I620K	Neutral	0.175
BRCA1	P38398-1.2	I620L	Neutral	0.027
BRCA1	P38398-1.2	I620M	Neutral	0.039
BRCA1	P38398-1.2	I620N	Neutral	0.237
BRCA1	P38398-1.2	I620P	Neutral	0.267
BRCA1	P38398-1.2	I620Q	Neutral	0.174
BRCA1	P38398-1.2	I620R	Neutral	0.22
BRCA1	P38398-1.2	I620S	Neutral	0.267
BRCA1	P38398-1.2	I620T	Neutral	0.14
BRCA1	P38398-1.2	I620V	Neutral	0.029
BRCA1	P38398-1.2	I620W	Neutral	0.292
BRCA1	P38398-1.2	I620Y	Neutral	0.108
BRCA1	P38398-1.2	H621A	Neutral	0.109
BRCA1	P38398-1.2	H621C	Neutral	0.102
BRCA1	P38398-1.2	H621D	Neutral	0.047
BRCA1	P38398-1.2	H621E	Neutral	0.022
BRCA1	P38398-1.2	H621F	Neutral	0.037
BRCA1	P38398-1.2	H621G	Neutral	0.157
BRCA1	P38398-1.2	H621I	Neutral	0.059
BRCA1	P38398-1.2	H621K	Neutral	0.038
BRCA1	P38398-1.2	H621L	Neutral	0.059
BRCA1	P38398-1.2	H621M	Neutral	0.042
BRCA1	P38398-1.2	H621N	Neutral	0.021
BRCA1	P38398-1.2	H621P	Neutral	0.068
BRCA1	P38398-1.2	H621Q	Neutral	0.02
BRCA1	P38398-1.2	H621R	Neutral	0.035
BRCA1	P38398-1.2	H621S	Neutral	0.069
BRCA1	P38398-1.2	H621T	Neutral	0.064
BRCA1	P38398-1.2	H621V	Neutral	0.069
BRCA1	P38398-1.2	H621W	Neutral	0.094
BRCA1	P38398-1.2	H621Y	Neutral	0.015
BRCA1	P38398-1.2	A622C	Neutral	0.144
BRCA1	P38398-1.2	A622D	Neutral	0.279
BRCA1	P38398-1.2	A622E	Neutral	0.287
BRCA1	P38398-1.2	A622F	Pathogenic	0.505
BRCA1	P38398-1.2	A622G	Neutral	0.145
BRCA1	P38398-1.2	A622H	Neutral	0.418
BRCA1	P38398-1.2	A622I	Neutral	0.357
BRCA1	P38398-1.2	A622K	Neutral	0.416
BRCA1	P38398-1.2	A622L	Neutral	0.358
BRCA1	P38398-1.2	A622M	Neutral	0.36
BRCA1	P38398-1.2	A622N	Neutral	0.303
BRCA1	P38398-1.2	A622P	Neutral	0.21
BRCA1	P38398-1.2	A622Q	Neutral	0.312
BRCA1	P38398-1.2	A622R	Neutral	0.487
BRCA1	P38398-1.2	A622S	Neutral	0.081
BRCA1	P38398-1.2	A622T	Neutral	0.166
BRCA1	P38398-1.2	A622V	Neutral	0.204
BRCA1	P38398-1.2	A622W	Pathogenic	0.731
BRCA1	P38398-1.2	A622Y	Pathogenic	0.542
BRCA1	P38398-1.2	L623A	Pathogenic	0.933
BRCA1	P38398-1.2	L623C	Pathogenic	0.902
BRCA1	P38398-1.2	L623D	Pathogenic	0.959
BRCA1	P38398-1.2	L623E	Pathogenic	0.917
BRCA1	P38398-1.2	L623F	Pathogenic	0.78
BRCA1	P38398-1.2	L623G	Pathogenic	0.984
BRCA1	P38398-1.2	L623H	Pathogenic	0.902
BRCA1	P38398-1.2	L623I	Pathogenic	0.573
BRCA1	P38398-1.2	L623K	Pathogenic	0.875
BRCA1	P38398-1.2	L623M	Pathogenic	0.571
BRCA1	P38398-1.2	L623N	Pathogenic	0.937
BRCA1	P38398-1.2	L623P	Pathogenic	0.945
BRCA1	P38398-1.2	L623Q	Pathogenic	0.874
BRCA1	P38398-1.2	L623R	Pathogenic	0.903
BRCA1	P38398-1.2	L623S	Pathogenic	0.945
BRCA1	P38398-1.2	L623T	Pathogenic	0.886
BRCA1	P38398-1.2	L623V	Pathogenic	0.745
BRCA1	P38398-1.2	L623W	Pathogenic	0.931
BRCA1	P38398-1.2	L623Y	Pathogenic	0.852
BRCA1	P38398-1.2	E624A	Pathogenic	0.849
BRCA1	P38398-1.2	E624C	Pathogenic	0.916
BRCA1	P38398-1.2	E624D	Pathogenic	0.53
BRCA1	P38398-1.2	E624F	Pathogenic	0.888
BRCA1	P38398-1.2	E624G	Pathogenic	0.926
BRCA1	P38398-1.2	E624H	Pathogenic	0.654
BRCA1	P38398-1.2	E624I	Pathogenic	0.862
BRCA1	P38398-1.2	E624K	Pathogenic	0.659
BRCA1	P38398-1.2	E624L	Pathogenic	0.862
BRCA1	P38398-1.2	E624M	Pathogenic	0.814
BRCA1	P38398-1.2	E624N	Pathogenic	0.677
BRCA1	P38398-1.2	E624P	Pathogenic	0.77
BRCA1	P38398-1.2	E624Q	Neutral	0.456
BRCA1	P38398-1.2	E624R	Pathogenic	0.787
BRCA1	P38398-1.2	E624S	Pathogenic	0.775
BRCA1	P38398-1.2	E624T	Pathogenic	0.76
BRCA1	P38398-1.2	E624V	Pathogenic	0.774
BRCA1	P38398-1.2	E624W	Pathogenic	0.936
BRCA1	P38398-1.2	E624Y	Pathogenic	0.865
BRCA1	P38398-1.2	L625A	Pathogenic	0.529
BRCA1	P38398-1.2	L625C	Neutral	0.427
BRCA1	P38398-1.2	L625D	Pathogenic	0.658
BRCA1	P38398-1.2	L625E	Neutral	0.473
BRCA1	P38398-1.2	L625F	Neutral	0.224
BRCA1	P38398-1.2	L625G	Pathogenic	0.835
BRCA1	P38398-1.2	L625H	Neutral	0.428
BRCA1	P38398-1.2	L625I	Neutral	0.098
BRCA1	P38398-1.2	L625K	Neutral	0.362
BRCA1	P38398-1.2	L625M	Neutral	0.098
BRCA1	P38398-1.2	L625N	Pathogenic	0.546
BRCA1	P38398-1.2	L625P	Pathogenic	0.585
BRCA1	P38398-1.2	L625Q	Neutral	0.361
BRCA1	P38398-1.2	L625R	Neutral	0.431
BRCA1	P38398-1.2	L625S	Pathogenic	0.584
BRCA1	P38398-1.2	L625T	Neutral	0.387
BRCA1	P38398-1.2	L625V	Neutral	0.192
BRCA1	P38398-1.2	L625W	Pathogenic	0.524
BRCA1	P38398-1.2	L625Y	Neutral	0.319
BRCA1	P38398-1.2	V626A	Neutral	0.326
BRCA1	P38398-1.2	V626C	Neutral	0.316
BRCA1	P38398-1.2	V626D	Neutral	0.453
BRCA1	P38398-1.2	V626E	Neutral	0.316
BRCA1	P38398-1.2	V626F	Neutral	0.369
BRCA1	P38398-1.2	V626G	Pathogenic	0.686
BRCA1	P38398-1.2	V626H	Neutral	0.451
BRCA1	P38398-1.2	V626I	Neutral	0.097
BRCA1	P38398-1.2	V626K	Neutral	0.449
BRCA1	P38398-1.2	V626L	Neutral	0.181
BRCA1	P38398-1.2	V626M	Neutral	0.183
BRCA1	P38398-1.2	V626N	Neutral	0.426
BRCA1	P38398-1.2	V626P	Neutral	0.377
BRCA1	P38398-1.2	V626Q	Neutral	0.342
BRCA1	P38398-1.2	V626R	Pathogenic	0.611
BRCA1	P38398-1.2	V626S	Neutral	0.465
BRCA1	P38398-1.2	V626T	Neutral	0.213
BRCA1	P38398-1.2	V626W	Pathogenic	0.691
BRCA1	P38398-1.2	V626Y	Neutral	0.402
BRCA1	P38398-1.2	V627A	Neutral	0.497
BRCA1	P38398-1.2	V627C	Neutral	0.486
BRCA1	P38398-1.2	V627D	Pathogenic	0.629
BRCA1	P38398-1.2	V627E	Neutral	0.486
BRCA1	P38398-1.2	V627F	Pathogenic	0.545
BRCA1	P38398-1.2	V627G	Pathogenic	0.817
BRCA1	P38398-1.2	V627H	Pathogenic	0.628
BRCA1	P38398-1.2	V627I	Neutral	0.18
BRCA1	P38398-1.2	V627K	Pathogenic	0.626
BRCA1	P38398-1.2	V627L	Neutral	0.312
BRCA1	P38398-1.2	V627M	Neutral	0.314
BRCA1	P38398-1.2	V627N	Pathogenic	0.603
BRCA1	P38398-1.2	V627P	Pathogenic	0.553
BRCA1	P38398-1.2	V627Q	Pathogenic	0.516
BRCA1	P38398-1.2	V627R	Pathogenic	0.763
BRCA1	P38398-1.2	V627S	Pathogenic	0.64
BRCA1	P38398-1.2	V627T	Neutral	0.357
BRCA1	P38398-1.2	V627W	Pathogenic	0.821
BRCA1	P38398-1.2	V627Y	Pathogenic	0.58
BRCA1	P38398-1.2	S628A	Neutral	0.01
BRCA1	P38398-1.2	S628C	Neutral	0.024
BRCA1	P38398-1.2	S628D	Neutral	0.019
BRCA1	P38398-1.2	S628E	Neutral	0.028
BRCA1	P38398-1.2	S628F	Neutral	0.095
BRCA1	P38398-1.2	S628G	Neutral	0.022
BRCA1	P38398-1.2	S628H	Neutral	0.049
BRCA1	P38398-1.2	S628I	Neutral	0.076
BRCA1	P38398-1.2	S628K	Neutral	0.049
BRCA1	P38398-1.2	S628L	Neutral	0.076
BRCA1	P38398-1.2	S628M	Neutral	0.054
BRCA1	P38398-1.2	S628N	Neutral	0.015
BRCA1	P38398-1.2	S628P	Neutral	0.027
BRCA1	P38398-1.2	S628Q	Neutral	0.032
BRCA1	P38398-1.2	S628R	Neutral	0.09
BRCA1	P38398-1.2	S628T	Neutral	0.014
BRCA1	P38398-1.2	S628V	Neutral	0.052
BRCA1	P38398-1.2	S628W	Neutral	0.218
BRCA1	P38398-1.2	S628Y	Neutral	0.108
BRCA1	P38398-1.2	R629A	Neutral	0.373
BRCA1	P38398-1.2	R629C	Neutral	0.443
BRCA1	P38398-1.2	R629D	Neutral	0.339
BRCA1	P38398-1.2	R629E	Neutral	0.142
BRCA1	P38398-1.2	R629F	Neutral	0.209
BRCA1	P38398-1.2	R629G	Pathogenic	0.567
BRCA1	P38398-1.2	R629H	Neutral	0.118
BRCA1	P38398-1.2	R629I	Neutral	0.252
BRCA1	P38398-1.2	R629K	Neutral	0.043
BRCA1	P38398-1.2	R629L	Neutral	0.19
BRCA1	P38398-1.2	R629M	Neutral	0.141
BRCA1	P38398-1.2	R629N	Neutral	0.181
BRCA1	P38398-1.2	R629P	Neutral	0.337
BRCA1	P38398-1.2	R629Q	Neutral	0.093
BRCA1	P38398-1.2	R629S	Neutral	0.344
BRCA1	P38398-1.2	R629T	Neutral	0.25
BRCA1	P38398-1.2	R629V	Neutral	0.342
BRCA1	P38398-1.2	R629W	Neutral	0.215
BRCA1	P38398-1.2	R629Y	Neutral	0.14
BRCA1	P38398-1.2	N630A	Neutral	0.287
BRCA1	P38398-1.2	N630C	Neutral	0.272
BRCA1	P38398-1.2	N630D	Neutral	0.074
BRCA1	P38398-1.2	N630E	Neutral	0.122
BRCA1	P38398-1.2	N630F	Neutral	0.413
BRCA1	P38398-1.2	N630G	Neutral	0.229
BRCA1	P38398-1.2	N630H	Neutral	0.104
BRCA1	P38398-1.2	N630I	Neutral	0.355
BRCA1	P38398-1.2	N630K	Neutral	0.197
BRCA1	P38398-1.2	N630L	Neutral	0.355
BRCA1	P38398-1.2	N630M	Neutral	0.279
BRCA1	P38398-1.2	N630P	Neutral	0.193
BRCA1	P38398-1.2	N630Q	Neutral	0.133
BRCA1	P38398-1.2	N630R	Neutral	0.246
BRCA1	P38398-1.2	N630S	Neutral	0.106
BRCA1	P38398-1.2	N630T	Neutral	0.098
BRCA1	P38398-1.2	N630V	Neutral	0.267
BRCA1	P38398-1.2	N630W	Pathogenic	0.651
BRCA1	P38398-1.2	N630Y	Neutral	0.362
BRCA1	P38398-1.2	L631A	Pathogenic	0.608
BRCA1	P38398-1.2	L631C	Pathogenic	0.507
BRCA1	P38398-1.2	L631D	Pathogenic	0.727
BRCA1	P38398-1.2	L631E	Pathogenic	0.554
BRCA1	P38398-1.2	L631F	Neutral	0.285
BRCA1	P38398-1.2	L631G	Pathogenic	0.875
BRCA1	P38398-1.2	L631H	Pathogenic	0.508
BRCA1	P38398-1.2	L631I	Neutral	0.131
BRCA1	P38398-1.2	L631K	Neutral	0.439
BRCA1	P38398-1.2	L631M	Neutral	0.13
BRCA1	P38398-1.2	L631N	Pathogenic	0.624
BRCA1	P38398-1.2	L631P	Pathogenic	0.66
BRCA1	P38398-1.2	L631Q	Neutral	0.437
BRCA1	P38398-1.2	L631R	Pathogenic	0.511
BRCA1	P38398-1.2	L631S	Pathogenic	0.66
BRCA1	P38398-1.2	L631T	Neutral	0.465
BRCA1	P38398-1.2	L631V	Neutral	0.247
BRCA1	P38398-1.2	L631W	Pathogenic	0.603
BRCA1	P38398-1.2	L631Y	Neutral	0.392
BRCA1	P38398-1.2	S632A	Pathogenic	0.607
BRCA1	P38398-1.2	S632C	Pathogenic	0.787
BRCA1	P38398-1.2	S632D	Pathogenic	0.742
BRCA1	P38398-1.2	S632E	Pathogenic	0.812
BRCA1	P38398-1.2	S632F	Pathogenic	0.939
BRCA1	P38398-1.2	S632G	Pathogenic	0.773
BRCA1	P38398-1.2	S632H	Pathogenic	0.884
BRCA1	P38398-1.2	S632I	Pathogenic	0.924
BRCA1	P38398-1.2	S632K	Pathogenic	0.884
BRCA1	P38398-1.2	S632L	Pathogenic	0.924
BRCA1	P38398-1.2	S632M	Pathogenic	0.895
BRCA1	P38398-1.2	S632N	Pathogenic	0.692
BRCA1	P38398-1.2	S632P	Pathogenic	0.802
BRCA1	P38398-1.2	S632Q	Pathogenic	0.829
BRCA1	P38398-1.2	S632R	Pathogenic	0.936
BRCA1	P38398-1.2	S632T	Pathogenic	0.679
BRCA1	P38398-1.2	S632V	Pathogenic	0.89
BRCA1	P38398-1.2	S632W	Pathogenic	0.976
BRCA1	P38398-1.2	S632Y	Pathogenic	0.947
BRCA1	P38398-1.2	P633A	Pathogenic	0.932
BRCA1	P38398-1.2	P633C	Pathogenic	0.95
BRCA1	P38398-1.2	P633D	Pathogenic	0.892
BRCA1	P38398-1.2	P633E	Pathogenic	0.925
BRCA1	P38398-1.2	P633F	Pathogenic	0.985
BRCA1	P38398-1.2	P633G	Pathogenic	0.968
BRCA1	P38398-1.2	P633H	Pathogenic	0.957
BRCA1	P38398-1.2	P633I	Pathogenic	0.973
BRCA1	P38398-1.2	P633K	Pathogenic	0.956
BRCA1	P38398-1.2	P633L	Pathogenic	0.973
BRCA1	P38398-1.2	P633M	Pathogenic	0.962
BRCA1	P38398-1.2	P633N	Pathogenic	0.93
BRCA1	P38398-1.2	P633Q	Pathogenic	0.933
BRCA1	P38398-1.2	P633R	Pathogenic	0.977
BRCA1	P38398-1.2	P633S	Pathogenic	0.923
BRCA1	P38398-1.2	P633T	Pathogenic	0.898
BRCA1	P38398-1.2	P633V	Pathogenic	0.943
BRCA1	P38398-1.2	P633W	Pathogenic	0.992
BRCA1	P38398-1.2	P633Y	Pathogenic	0.982
BRCA1	P38398-1.2	P634A	Pathogenic	0.865
BRCA1	P38398-1.2	P634C	Pathogenic	0.897
BRCA1	P38398-1.2	P634D	Pathogenic	0.794
BRCA1	P38398-1.2	P634E	Pathogenic	0.852
BRCA1	P38398-1.2	P634F	Pathogenic	0.968
BRCA1	P38398-1.2	P634G	Pathogenic	0.933
BRCA1	P38398-1.2	P634H	Pathogenic	0.911
BRCA1	P38398-1.2	P634I	Pathogenic	0.944
BRCA1	P38398-1.2	P634K	Pathogenic	0.911
BRCA1	P38398-1.2	P634L	Pathogenic	0.944
BRCA1	P38398-1.2	P634M	Pathogenic	0.922
BRCA1	P38398-1.2	P634N	Pathogenic	0.861
BRCA1	P38398-1.2	P634Q	Pathogenic	0.866
BRCA1	P38398-1.2	P634R	Pathogenic	0.951
BRCA1	P38398-1.2	P634S	Pathogenic	0.848
BRCA1	P38398-1.2	P634T	Pathogenic	0.804
BRCA1	P38398-1.2	P634V	Pathogenic	0.885
BRCA1	P38398-1.2	P634W	Pathogenic	0.983
BRCA1	P38398-1.2	P634Y	Pathogenic	0.961
BRCA1	P38398-1.2	N635A	Neutral	0.035
BRCA1	P38398-1.2	N635C	Neutral	0.033
BRCA1	P38398-1.2	N635D	Neutral	0.007
BRCA1	P38398-1.2	N635E	Neutral	0.012
BRCA1	P38398-1.2	N635F	Neutral	0.059
BRCA1	P38398-1.2	N635G	Neutral	0.026
BRCA1	P38398-1.2	N635H	Neutral	0.01
BRCA1	P38398-1.2	N635I	Neutral	0.047
BRCA1	P38398-1.2	N635K	Neutral	0.022
BRCA1	P38398-1.2	N635L	Neutral	0.047
BRCA1	P38398-1.2	N635M	Neutral	0.034
BRCA1	P38398-1.2	N635P	Neutral	0.021
BRCA1	P38398-1.2	N635Q	Neutral	0.014
BRCA1	P38398-1.2	N635R	Neutral	0.028
BRCA1	P38398-1.2	N635S	Neutral	0.011
BRCA1	P38398-1.2	N635T	Neutral	0.01
BRCA1	P38398-1.2	N635V	Neutral	0.032
BRCA1	P38398-1.2	N635W	Neutral	0.143
BRCA1	P38398-1.2	N635Y	Neutral	0.048
BRCA1	P38398-1.2	C636A	Neutral	0.01
BRCA1	P38398-1.2	C636D	Neutral	0.021
BRCA1	P38398-1.2	C636E	Neutral	0.044
BRCA1	P38398-1.2	C636F	Neutral	0.039
BRCA1	P38398-1.2	C636G	Neutral	0.043
BRCA1	P38398-1.2	C636H	Neutral	0.038
BRCA1	P38398-1.2	C636I	Neutral	0.021
BRCA1	P38398-1.2	C636K	Neutral	0.053
BRCA1	P38398-1.2	C636L	Neutral	0.021
BRCA1	P38398-1.2	C636M	Neutral	0.022
BRCA1	P38398-1.2	C636N	Neutral	0.023
BRCA1	P38398-1.2	C636P	Neutral	0.021
BRCA1	P38398-1.2	C636Q	Neutral	0.035
BRCA1	P38398-1.2	C636R	Neutral	0.07
BRCA1	P38398-1.2	C636S	Neutral	0.012
BRCA1	P38398-1.2	C636T	Neutral	0.011
BRCA1	P38398-1.2	C636V	Neutral	0.014
BRCA1	P38398-1.2	C636W	Neutral	0.069
BRCA1	P38398-1.2	C636Y	Neutral	0.044
BRCA1	P38398-1.2	T637A	Neutral	0.455
BRCA1	P38398-1.2	T637C	Neutral	0.438
BRCA1	P38398-1.2	T637D	Neutral	0.409
BRCA1	P38398-1.2	T637E	Neutral	0.487
BRCA1	P38398-1.2	T637F	Pathogenic	0.706
BRCA1	P38398-1.2	T637G	Pathogenic	0.725
BRCA1	P38398-1.2	T637H	Pathogenic	0.628
BRCA1	P38398-1.2	T637I	Pathogenic	0.566
BRCA1	P38398-1.2	T637K	Pathogenic	0.627
BRCA1	P38398-1.2	T637L	Pathogenic	0.567
BRCA1	P38398-1.2	T637M	Pathogenic	0.569
BRCA1	P38398-1.2	T637N	Neutral	0.331
BRCA1	P38398-1.2	T637P	Neutral	0.417
BRCA1	P38398-1.2	T637Q	Pathogenic	0.516
BRCA1	P38398-1.2	T637R	Pathogenic	0.691
BRCA1	P38398-1.2	T637S	Neutral	0.336
BRCA1	P38398-1.2	T637V	Neutral	0.376
BRCA1	P38398-1.2	T637W	Pathogenic	0.816
BRCA1	P38398-1.2	T637Y	Pathogenic	0.736
BRCA1	P38398-1.2	E638A	Pathogenic	0.894
BRCA1	P38398-1.2	E638C	Pathogenic	0.942
BRCA1	P38398-1.2	E638D	Pathogenic	0.628
BRCA1	P38398-1.2	E638F	Pathogenic	0.923
BRCA1	P38398-1.2	E638G	Pathogenic	0.949
BRCA1	P38398-1.2	E638H	Pathogenic	0.739
BRCA1	P38398-1.2	E638I	Pathogenic	0.903
BRCA1	P38398-1.2	E638K	Pathogenic	0.743
BRCA1	P38398-1.2	E638L	Pathogenic	0.903
BRCA1	P38398-1.2	E638M	Pathogenic	0.868
BRCA1	P38398-1.2	E638N	Pathogenic	0.758
BRCA1	P38398-1.2	E638P	Pathogenic	0.834
BRCA1	P38398-1.2	E638Q	Pathogenic	0.557
BRCA1	P38398-1.2	E638R	Pathogenic	0.847
BRCA1	P38398-1.2	E638S	Pathogenic	0.838
BRCA1	P38398-1.2	E638T	Pathogenic	0.826
BRCA1	P38398-1.2	E638V	Pathogenic	0.837
BRCA1	P38398-1.2	E638W	Pathogenic	0.957
BRCA1	P38398-1.2	E638Y	Pathogenic	0.906
BRCA1	P38398-1.2	L639A	Pathogenic	0.963
BRCA1	P38398-1.2	L639C	Pathogenic	0.945
BRCA1	P38398-1.2	L639D	Pathogenic	0.978
BRCA1	P38398-1.2	L639E	Pathogenic	0.954
BRCA1	P38398-1.2	L639F	Pathogenic	0.869
BRCA1	P38398-1.2	L639G	Pathogenic	0.992
BRCA1	P38398-1.2	L639H	Pathogenic	0.945
BRCA1	P38398-1.2	L639I	Pathogenic	0.715
BRCA1	P38398-1.2	L639K	Pathogenic	0.929
BRCA1	P38398-1.2	L639M	Pathogenic	0.713
BRCA1	P38398-1.2	L639N	Pathogenic	0.965
BRCA1	P38398-1.2	L639P	Pathogenic	0.97
BRCA1	P38398-1.2	L639Q	Pathogenic	0.928
BRCA1	P38398-1.2	L639R	Pathogenic	0.946
BRCA1	P38398-1.2	L639S	Pathogenic	0.97
BRCA1	P38398-1.2	L639T	Pathogenic	0.935
BRCA1	P38398-1.2	L639V	Pathogenic	0.845
BRCA1	P38398-1.2	L639W	Pathogenic	0.962
BRCA1	P38398-1.2	L639Y	Pathogenic	0.915
BRCA1	P38398-1.2	Q640A	Pathogenic	0.969
BRCA1	P38398-1.2	Q640C	Pathogenic	0.977
BRCA1	P38398-1.2	Q640D	Pathogenic	0.928
BRCA1	P38398-1.2	Q640E	Pathogenic	0.807
BRCA1	P38398-1.2	Q640F	Pathogenic	0.973
BRCA1	P38398-1.2	Q640G	Pathogenic	0.986
BRCA1	P38398-1.2	Q640H	Pathogenic	0.895
BRCA1	P38398-1.2	Q640I	Pathogenic	0.966
BRCA1	P38398-1.2	Q640K	Pathogenic	0.895
BRCA1	P38398-1.2	Q640L	Pathogenic	0.951
BRCA1	P38398-1.2	Q640M	Pathogenic	0.905
BRCA1	P38398-1.2	Q640N	Pathogenic	0.921
BRCA1	P38398-1.2	Q640P	Pathogenic	0.95
BRCA1	P38398-1.2	Q640R	Pathogenic	0.919
BRCA1	P38398-1.2	Q640S	Pathogenic	0.951
BRCA1	P38398-1.2	Q640T	Pathogenic	0.947
BRCA1	P38398-1.2	Q640V	Pathogenic	0.951
BRCA1	P38398-1.2	Q640W	Pathogenic	0.979
BRCA1	P38398-1.2	Q640Y	Pathogenic	0.953
BRCA1	P38398-1.2	I641A	Pathogenic	0.938
BRCA1	P38398-1.2	I641C	Pathogenic	0.909
BRCA1	P38398-1.2	I641D	Pathogenic	0.947
BRCA1	P38398-1.2	I641E	Pathogenic	0.924
BRCA1	P38398-1.2	I641F	Pathogenic	0.795
BRCA1	P38398-1.2	I641G	Pathogenic	0.986
BRCA1	P38398-1.2	I641H	Pathogenic	0.909
BRCA1	P38398-1.2	I641K	Pathogenic	0.917
BRCA1	P38398-1.2	I641L	Pathogenic	0.595
BRCA1	P38398-1.2	I641M	Pathogenic	0.677
BRCA1	P38398-1.2	I641N	Pathogenic	0.942
BRCA1	P38398-1.2	I641P	Pathogenic	0.95
BRCA1	P38398-1.2	I641Q	Pathogenic	0.916
BRCA1	P38398-1.2	I641R	Pathogenic	0.936
BRCA1	P38398-1.2	I641S	Pathogenic	0.95
BRCA1	P38398-1.2	I641T	Pathogenic	0.894
BRCA1	P38398-1.2	I641V	Pathogenic	0.607
BRCA1	P38398-1.2	I641W	Pathogenic	0.955
BRCA1	P38398-1.2	I641Y	Pathogenic	0.863
BRCA1	P38398-1.2	D642A	Pathogenic	0.908
BRCA1	P38398-1.2	D642C	Pathogenic	0.902
BRCA1	P38398-1.2	D642E	Pathogenic	0.671
BRCA1	P38398-1.2	D642F	Pathogenic	0.955
BRCA1	P38398-1.2	D642G	Pathogenic	0.913
BRCA1	P38398-1.2	D642H	Pathogenic	0.88
BRCA1	P38398-1.2	D642I	Pathogenic	0.944
BRCA1	P38398-1.2	D642K	Pathogenic	0.915
BRCA1	P38398-1.2	D642L	Pathogenic	0.96
BRCA1	P38398-1.2	D642M	Pathogenic	0.944
BRCA1	P38398-1.2	D642N	Pathogenic	0.688
BRCA1	P38398-1.2	D642P	Pathogenic	0.803
BRCA1	P38398-1.2	D642Q	Pathogenic	0.824
BRCA1	P38398-1.2	D642R	Pathogenic	0.954
BRCA1	P38398-1.2	D642S	Pathogenic	0.807
BRCA1	P38398-1.2	D642T	Pathogenic	0.807
BRCA1	P38398-1.2	D642V	Pathogenic	0.918
BRCA1	P38398-1.2	D642W	Pathogenic	0.983
BRCA1	P38398-1.2	D642Y	Pathogenic	0.961
BRCA1	P38398-1.2	S643A	Pathogenic	0.514
BRCA1	P38398-1.2	S643C	Pathogenic	0.717
BRCA1	P38398-1.2	S643D	Pathogenic	0.664
BRCA1	P38398-1.2	S643E	Pathogenic	0.747
BRCA1	P38398-1.2	S643F	Pathogenic	0.914
BRCA1	P38398-1.2	S643G	Pathogenic	0.701
BRCA1	P38398-1.2	S643H	Pathogenic	0.84
BRCA1	P38398-1.2	S643I	Pathogenic	0.893
BRCA1	P38398-1.2	S643K	Pathogenic	0.839
BRCA1	P38398-1.2	S643L	Pathogenic	0.893
BRCA1	P38398-1.2	S643M	Pathogenic	0.854
BRCA1	P38398-1.2	S643N	Pathogenic	0.606
BRCA1	P38398-1.2	S643P	Pathogenic	0.735
BRCA1	P38398-1.2	S643Q	Pathogenic	0.769
BRCA1	P38398-1.2	S643R	Pathogenic	0.909
BRCA1	P38398-1.2	S643T	Pathogenic	0.591
BRCA1	P38398-1.2	S643V	Pathogenic	0.847
BRCA1	P38398-1.2	S643W	Pathogenic	0.966
BRCA1	P38398-1.2	S643Y	Pathogenic	0.925
BRCA1	P38398-1.2	C644A	Neutral	0.193
BRCA1	P38398-1.2	C644D	Neutral	0.338
BRCA1	P38398-1.2	C644E	Pathogenic	0.524
BRCA1	P38398-1.2	C644F	Neutral	0.49
BRCA1	P38398-1.2	C644G	Pathogenic	0.519
BRCA1	P38398-1.2	C644H	Neutral	0.486
BRCA1	P38398-1.2	C644I	Neutral	0.343
BRCA1	P38398-1.2	C644K	Pathogenic	0.575
BRCA1	P38398-1.2	C644L	Neutral	0.344
BRCA1	P38398-1.2	C644M	Neutral	0.346
BRCA1	P38398-1.2	C644N	Neutral	0.364
BRCA1	P38398-1.2	C644P	Neutral	0.34
BRCA1	P38398-1.2	C644Q	Neutral	0.462
BRCA1	P38398-1.2	C644R	Pathogenic	0.643
BRCA1	P38398-1.2	C644S	Neutral	0.23
BRCA1	P38398-1.2	C644T	Neutral	0.208
BRCA1	P38398-1.2	C644V	Neutral	0.257
BRCA1	P38398-1.2	C644W	Pathogenic	0.639
BRCA1	P38398-1.2	C644Y	Pathogenic	0.527
BRCA1	P38398-1.2	S645A	Neutral	0.069
BRCA1	P38398-1.2	S645C	Neutral	0.151
BRCA1	P38398-1.2	S645D	Neutral	0.122
BRCA1	P38398-1.2	S645E	Neutral	0.172
BRCA1	P38398-1.2	S645F	Neutral	0.428
BRCA1	P38398-1.2	S645G	Neutral	0.141
BRCA1	P38398-1.2	S645H	Neutral	0.269
BRCA1	P38398-1.2	S645I	Neutral	0.37
BRCA1	P38398-1.2	S645K	Neutral	0.269
BRCA1	P38398-1.2	S645L	Neutral	0.37
BRCA1	P38398-1.2	S645M	Neutral	0.292
BRCA1	P38398-1.2	S645N	Neutral	0.098
BRCA1	P38398-1.2	S645P	Neutral	0.164
BRCA1	P38398-1.2	S645Q	Neutral	0.19
BRCA1	P38398-1.2	S645R	Neutral	0.414
BRCA1	P38398-1.2	S645T	Neutral	0.092
BRCA1	P38398-1.2	S645V	Neutral	0.28
BRCA1	P38398-1.2	S645W	Pathogenic	0.666
BRCA1	P38398-1.2	S645Y	Neutral	0.465
BRCA1	P38398-1.2	S646A	Pathogenic	0.86
BRCA1	P38398-1.2	S646C	Pathogenic	0.936
BRCA1	P38398-1.2	S646D	Pathogenic	0.92
BRCA1	P38398-1.2	S646E	Pathogenic	0.945
BRCA1	P38398-1.2	S646F	Pathogenic	0.984
BRCA1	P38398-1.2	S646G	Pathogenic	0.931
BRCA1	P38398-1.2	S646H	Pathogenic	0.968
BRCA1	P38398-1.2	S646I	Pathogenic	0.98
BRCA1	P38398-1.2	S646K	Pathogenic	0.968
BRCA1	P38398-1.2	S646L	Pathogenic	0.98
BRCA1	P38398-1.2	S646M	Pathogenic	0.971
BRCA1	P38398-1.2	S646N	Pathogenic	0.899
BRCA1	P38398-1.2	S646P	Pathogenic	0.942
BRCA1	P38398-1.2	S646Q	Pathogenic	0.951
BRCA1	P38398-1.2	S646R	Pathogenic	0.983
BRCA1	P38398-1.2	S646T	Pathogenic	0.894
BRCA1	P38398-1.2	S646V	Pathogenic	0.97
BRCA1	P38398-1.2	S646W	Pathogenic	0.994
BRCA1	P38398-1.2	S646Y	Pathogenic	0.986
BRCA1	P38398-1.2	S647A	Neutral	0.105
BRCA1	P38398-1.2	S647C	Neutral	0.219
BRCA1	P38398-1.2	S647D	Neutral	0.18
BRCA1	P38398-1.2	S647E	Neutral	0.247
BRCA1	P38398-1.2	S647F	Pathogenic	0.542
BRCA1	P38398-1.2	S647G	Neutral	0.206
BRCA1	P38398-1.2	S647H	Neutral	0.368
BRCA1	P38398-1.2	S647I	Neutral	0.481
BRCA1	P38398-1.2	S647K	Neutral	0.367
BRCA1	P38398-1.2	S647L	Neutral	0.481
BRCA1	P38398-1.2	S647M	Neutral	0.394
BRCA1	P38398-1.2	S647N	Neutral	0.146
BRCA1	P38398-1.2	S647P	Neutral	0.236
BRCA1	P38398-1.2	S647Q	Neutral	0.27
BRCA1	P38398-1.2	S647R	Pathogenic	0.527
BRCA1	P38398-1.2	S647T	Neutral	0.139
BRCA1	P38398-1.2	S647V	Neutral	0.381
BRCA1	P38398-1.2	S647W	Pathogenic	0.759
BRCA1	P38398-1.2	S647Y	Pathogenic	0.579
BRCA1	P38398-1.2	E648A	Pathogenic	0.985
BRCA1	P38398-1.2	E648C	Pathogenic	0.992
BRCA1	P38398-1.2	E648D	Pathogenic	0.929
BRCA1	P38398-1.2	E648F	Pathogenic	0.989
BRCA1	P38398-1.2	E648G	Pathogenic	0.993
BRCA1	P38398-1.2	E648H	Pathogenic	0.956
BRCA1	P38398-1.2	E648I	Pathogenic	0.986
BRCA1	P38398-1.2	E648K	Pathogenic	0.957
BRCA1	P38398-1.2	E648L	Pathogenic	0.986
BRCA1	P38398-1.2	E648M	Pathogenic	0.981
BRCA1	P38398-1.2	E648N	Pathogenic	0.96
BRCA1	P38398-1.2	E648P	Pathogenic	0.975
BRCA1	P38398-1.2	E648Q	Pathogenic	0.907
BRCA1	P38398-1.2	E648R	Pathogenic	0.977
BRCA1	P38398-1.2	E648S	Pathogenic	0.976
BRCA1	P38398-1.2	E648T	Pathogenic	0.973
BRCA1	P38398-1.2	E648V	Pathogenic	0.975
BRCA1	P38398-1.2	E648W	Pathogenic	0.994
BRCA1	P38398-1.2	E648Y	Pathogenic	0.987
BRCA1	P38398-1.2	E649A	Pathogenic	0.967
BRCA1	P38398-1.2	E649C	Pathogenic	0.983
BRCA1	P38398-1.2	E649D	Pathogenic	0.854
BRCA1	P38398-1.2	E649F	Pathogenic	0.976
BRCA1	P38398-1.2	E649G	Pathogenic	0.985
BRCA1	P38398-1.2	E649H	Pathogenic	0.908
BRCA1	P38398-1.2	E649I	Pathogenic	0.97
BRCA1	P38398-1.2	E649K	Pathogenic	0.909
BRCA1	P38398-1.2	E649L	Pathogenic	0.97
BRCA1	P38398-1.2	E649M	Pathogenic	0.958
BRCA1	P38398-1.2	E649N	Pathogenic	0.916
BRCA1	P38398-1.2	E649P	Pathogenic	0.946
BRCA1	P38398-1.2	E649Q	Pathogenic	0.814
BRCA1	P38398-1.2	E649R	Pathogenic	0.951
BRCA1	P38398-1.2	E649S	Pathogenic	0.947
BRCA1	P38398-1.2	E649T	Pathogenic	0.943
BRCA1	P38398-1.2	E649V	Pathogenic	0.947
BRCA1	P38398-1.2	E649W	Pathogenic	0.987
BRCA1	P38398-1.2	E649Y	Pathogenic	0.971
BRCA1	P38398-1.2	I650A	Neutral	0.005
BRCA1	P38398-1.2	I650C	Neutral	0.003
BRCA1	P38398-1.2	I650D	Neutral	0.005
BRCA1	P38398-1.2	I650E	Neutral	0.004
BRCA1	P38398-1.2	I650F	Neutral	0.001
BRCA1	P38398-1.2	I650G	Neutral	0.02
BRCA1	P38398-1.2	I650H	Neutral	0.003
BRCA1	P38398-1.2	I650K	Neutral	0.003
BRCA1	P38398-1.2	I650L	Neutral	0.0
BRCA1	P38398-1.2	I650M	Neutral	0.001
BRCA1	P38398-1.2	I650N	Neutral	0.005
BRCA1	P38398-1.2	I650P	Neutral	0.006
BRCA1	P38398-1.2	I650Q	Neutral	0.003
BRCA1	P38398-1.2	I650R	Neutral	0.004
BRCA1	P38398-1.2	I650S	Neutral	0.006
BRCA1	P38398-1.2	I650T	Neutral	0.003
BRCA1	P38398-1.2	I650V	Neutral	0.0
BRCA1	P38398-1.2	I650W	Neutral	0.006
BRCA1	P38398-1.2	I650Y	Neutral	0.002
BRCA1	P38398-1.2	K651A	Pathogenic	0.698
BRCA1	P38398-1.2	K651C	Pathogenic	0.756
BRCA1	P38398-1.2	K651D	Pathogenic	0.58
BRCA1	P38398-1.2	K651E	Neutral	0.309
BRCA1	P38398-1.2	K651F	Pathogenic	0.506
BRCA1	P38398-1.2	K651G	Pathogenic	0.836
BRCA1	P38398-1.2	K651H	Neutral	0.427
BRCA1	P38398-1.2	K651I	Pathogenic	0.567
BRCA1	P38398-1.2	K651L	Neutral	0.477
BRCA1	P38398-1.2	K651M	Neutral	0.39
BRCA1	P38398-1.2	K651N	Neutral	0.462
BRCA1	P38398-1.2	K651P	Pathogenic	0.579
BRCA1	P38398-1.2	K651Q	Neutral	0.284
BRCA1	P38398-1.2	K651R	Neutral	0.19
BRCA1	P38398-1.2	K651S	Pathogenic	0.586
BRCA1	P38398-1.2	K651T	Pathogenic	0.565
BRCA1	P38398-1.2	K651V	Pathogenic	0.584
BRCA1	P38398-1.2	K651W	Pathogenic	0.655
BRCA1	P38398-1.2	K651Y	Neutral	0.453
BRCA1	P38398-1.2	K652A	Neutral	0.055
BRCA1	P38398-1.2	K652C	Neutral	0.072
BRCA1	P38398-1.2	K652D	Neutral	0.034
BRCA1	P38398-1.2	K652E	Neutral	0.011
BRCA1	P38398-1.2	K652F	Neutral	0.025
BRCA1	P38398-1.2	K652G	Neutral	0.114
BRCA1	P38398-1.2	K652H	Neutral	0.018
BRCA1	P38398-1.2	K652I	Neutral	0.032
BRCA1	P38398-1.2	K652L	Neutral	0.022
BRCA1	P38398-1.2	K652M	Neutral	0.016
BRCA1	P38398-1.2	K652N	Neutral	0.021
BRCA1	P38398-1.2	K652P	Neutral	0.033
BRCA1	P38398-1.2	K652Q	Neutral	0.01
BRCA1	P38398-1.2	K652R	Neutral	0.006
BRCA1	P38398-1.2	K652S	Neutral	0.034
BRCA1	P38398-1.2	K652T	Neutral	0.032
BRCA1	P38398-1.2	K652V	Neutral	0.034
BRCA1	P38398-1.2	K652W	Neutral	0.045
BRCA1	P38398-1.2	K652Y	Neutral	0.02
BRCA1	P38398-1.2	K653A	Neutral	0.185
BRCA1	P38398-1.2	K653C	Neutral	0.234
BRCA1	P38398-1.2	K653D	Neutral	0.12
BRCA1	P38398-1.2	K653E	Neutral	0.042
BRCA1	P38398-1.2	K653F	Neutral	0.092
BRCA1	P38398-1.2	K653G	Neutral	0.334
BRCA1	P38398-1.2	K653H	Neutral	0.069
BRCA1	P38398-1.2	K653I	Neutral	0.114
BRCA1	P38398-1.2	K653L	Neutral	0.082
BRCA1	P38398-1.2	K653M	Neutral	0.059
BRCA1	P38398-1.2	K653N	Neutral	0.078
BRCA1	P38398-1.2	K653P	Neutral	0.119
BRCA1	P38398-1.2	K653Q	Neutral	0.038
BRCA1	P38398-1.2	K653R	Neutral	0.023
BRCA1	P38398-1.2	K653S	Neutral	0.122
BRCA1	P38398-1.2	K653T	Neutral	0.113
BRCA1	P38398-1.2	K653V	Neutral	0.122
BRCA1	P38398-1.2	K653W	Neutral	0.157
BRCA1	P38398-1.2	K653Y	Neutral	0.075
BRCA1	P38398-1.2	K654A	Neutral	0.014
BRCA1	P38398-1.2	K654C	Neutral	0.019
BRCA1	P38398-1.2	K654D	Neutral	0.009
BRCA1	P38398-1.2	K654E	Neutral	0.003
BRCA1	P38398-1.2	K654F	Neutral	0.006
BRCA1	P38398-1.2	K654G	Neutral	0.031
BRCA1	P38398-1.2	K654H	Neutral	0.005
BRCA1	P38398-1.2	K654I	Neutral	0.008
BRCA1	P38398-1.2	K654L	Neutral	0.006
BRCA1	P38398-1.2	K654M	Neutral	0.004
BRCA1	P38398-1.2	K654N	Neutral	0.005
BRCA1	P38398-1.2	K654P	Neutral	0.009
BRCA1	P38398-1.2	K654Q	Neutral	0.003
BRCA1	P38398-1.2	K654R	Neutral	0.001
BRCA1	P38398-1.2	K654S	Neutral	0.009
BRCA1	P38398-1.2	K654T	Neutral	0.008
BRCA1	P38398-1.2	K654V	Neutral	0.009
BRCA1	P38398-1.2	K654W	Neutral	0.012
BRCA1	P38398-1.2	K654Y	Neutral	0.005
BRCA1	P38398-1.2	Y655A	Pathogenic	0.543
BRCA1	P38398-1.2	Y655C	Neutral	0.441
BRCA1	P38398-1.2	Y655D	Neutral	0.496
BRCA1	P38398-1.2	Y655E	Neutral	0.315
BRCA1	P38398-1.2	Y655F	Neutral	0.041
BRCA1	P38398-1.2	Y655G	Pathogenic	0.722
BRCA1	P38398-1.2	Y655H	Neutral	0.082
BRCA1	P38398-1.2	Y655I	Neutral	0.188
BRCA1	P38398-1.2	Y655K	Neutral	0.204
BRCA1	P38398-1.2	Y655L	Neutral	0.189
BRCA1	P38398-1.2	Y655M	Neutral	0.19
BRCA1	P38398-1.2	Y655N	Neutral	0.38
BRCA1	P38398-1.2	Y655P	Pathogenic	0.509
BRCA1	P38398-1.2	Y655Q	Neutral	0.224
BRCA1	P38398-1.2	Y655R	Neutral	0.208
BRCA1	P38398-1.2	Y655S	Pathogenic	0.508
BRCA1	P38398-1.2	Y655T	Neutral	0.4
BRCA1	P38398-1.2	Y655V	Neutral	0.264
BRCA1	P38398-1.2	Y655W	Neutral	0.079
BRCA1	P38398-1.2	N656A	Neutral	0.002
BRCA1	P38398-1.2	N656C	Neutral	0.002
BRCA1	P38398-1.2	N656D	Neutral	0.0
BRCA1	P38398-1.2	N656E	Neutral	0.001
BRCA1	P38398-1.2	N656F	Neutral	0.003
BRCA1	P38398-1.2	N656G	Neutral	0.001
BRCA1	P38398-1.2	N656H	Neutral	0.001
BRCA1	P38398-1.2	N656I	Neutral	0.003
BRCA1	P38398-1.2	N656K	Neutral	0.001
BRCA1	P38398-1.2	N656L	Neutral	0.003
BRCA1	P38398-1.2	N656M	Neutral	0.002
BRCA1	P38398-1.2	N656P	Neutral	0.001
BRCA1	P38398-1.2	N656Q	Neutral	0.001
BRCA1	P38398-1.2	N656R	Neutral	0.001
BRCA1	P38398-1.2	N656S	Neutral	0.001
BRCA1	P38398-1.2	N656T	Neutral	0.001
BRCA1	P38398-1.2	N656V	Neutral	0.002
BRCA1	P38398-1.2	N656W	Neutral	0.009
BRCA1	P38398-1.2	N656Y	Neutral	0.003
BRCA1	P38398-1.2	Q657A	Pathogenic	0.957
BRCA1	P38398-1.2	Q657C	Pathogenic	0.968
BRCA1	P38398-1.2	Q657D	Pathogenic	0.901
BRCA1	P38398-1.2	Q657E	Pathogenic	0.747
BRCA1	P38398-1.2	Q657F	Pathogenic	0.962
BRCA1	P38398-1.2	Q657G	Pathogenic	0.98
BRCA1	P38398-1.2	Q657H	Pathogenic	0.857
BRCA1	P38398-1.2	Q657I	Pathogenic	0.952
BRCA1	P38398-1.2	Q657K	Pathogenic	0.857
BRCA1	P38398-1.2	Q657L	Pathogenic	0.932
BRCA1	P38398-1.2	Q657M	Pathogenic	0.87
BRCA1	P38398-1.2	Q657N	Pathogenic	0.891
BRCA1	P38398-1.2	Q657P	Pathogenic	0.93
BRCA1	P38398-1.2	Q657R	Pathogenic	0.889
BRCA1	P38398-1.2	Q657S	Pathogenic	0.932
BRCA1	P38398-1.2	Q657T	Pathogenic	0.926
BRCA1	P38398-1.2	Q657V	Pathogenic	0.931
BRCA1	P38398-1.2	Q657W	Pathogenic	0.97
BRCA1	P38398-1.2	Q657Y	Pathogenic	0.934
BRCA1	P38398-1.2	M658A	Neutral	0.03
BRCA1	P38398-1.2	M658C	Neutral	0.02
BRCA1	P38398-1.2	M658D	Neutral	0.036
BRCA1	P38398-1.2	M658E	Neutral	0.017
BRCA1	P38398-1.2	M658F	Neutral	0.008
BRCA1	P38398-1.2	M658G	Neutral	0.089
BRCA1	P38398-1.2	M658H	Neutral	0.014
BRCA1	P38398-1.2	M658I	Neutral	0.004
BRCA1	P38398-1.2	M658K	Neutral	0.011
BRCA1	P38398-1.2	M658L	Neutral	0.003
BRCA1	P38398-1.2	M658N	Neutral	0.023
BRCA1	P38398-1.2	M658P	Neutral	0.026
BRCA1	P38398-1.2	M658Q	Neutral	0.007
BRCA1	P38398-1.2	M658R	Neutral	0.014
BRCA1	P38398-1.2	M658S	Neutral	0.026
BRCA1	P38398-1.2	M658T	Neutral	0.017
BRCA1	P38398-1.2	M658V	Neutral	0.007
BRCA1	P38398-1.2	M658W	Neutral	0.02
BRCA1	P38398-1.2	M658Y	Neutral	0.013
BRCA1	P38398-1.2	P659A	Neutral	0.488
BRCA1	P38398-1.2	P659C	Pathogenic	0.565
BRCA1	P38398-1.2	P659D	Neutral	0.364
BRCA1	P38398-1.2	P659E	Neutral	0.461
BRCA1	P38398-1.2	P659F	Pathogenic	0.82
BRCA1	P38398-1.2	P659G	Pathogenic	0.675
BRCA1	P38398-1.2	P659H	Pathogenic	0.604
BRCA1	P38398-1.2	P659I	Pathogenic	0.713
BRCA1	P38398-1.2	P659K	Pathogenic	0.602
BRCA1	P38398-1.2	P659L	Pathogenic	0.714
BRCA1	P38398-1.2	P659M	Pathogenic	0.636
BRCA1	P38398-1.2	P659N	Neutral	0.48
BRCA1	P38398-1.2	P659Q	Neutral	0.491
BRCA1	P38398-1.2	P659R	Pathogenic	0.744
BRCA1	P38398-1.2	P659S	Neutral	0.453
BRCA1	P38398-1.2	P659T	Neutral	0.379
BRCA1	P38398-1.2	P659V	Pathogenic	0.534
BRCA1	P38398-1.2	P659W	Pathogenic	0.894
BRCA1	P38398-1.2	P659Y	Pathogenic	0.787
BRCA1	P38398-1.2	V660A	Neutral	0.148
BRCA1	P38398-1.2	V660C	Neutral	0.143
BRCA1	P38398-1.2	V660D	Neutral	0.23
BRCA1	P38398-1.2	V660E	Neutral	0.143
BRCA1	P38398-1.2	V660F	Neutral	0.174
BRCA1	P38398-1.2	V660G	Neutral	0.44
BRCA1	P38398-1.2	V660H	Neutral	0.229
BRCA1	P38398-1.2	V660I	Neutral	0.037
BRCA1	P38398-1.2	V660K	Neutral	0.227
BRCA1	P38398-1.2	V660L	Neutral	0.074
BRCA1	P38398-1.2	V660M	Neutral	0.075
BRCA1	P38398-1.2	V660N	Neutral	0.211
BRCA1	P38398-1.2	V660P	Neutral	0.179
BRCA1	P38398-1.2	V660Q	Neutral	0.158
BRCA1	P38398-1.2	V660R	Neutral	0.361
BRCA1	P38398-1.2	V660S	Neutral	0.239
BRCA1	P38398-1.2	V660T	Neutral	0.089
BRCA1	P38398-1.2	V660W	Neutral	0.447
BRCA1	P38398-1.2	V660Y	Neutral	0.195
BRCA1	P38398-1.2	R661A	Pathogenic	0.816
BRCA1	P38398-1.2	R661C	Pathogenic	0.856
BRCA1	P38398-1.2	R661D	Pathogenic	0.793
BRCA1	P38398-1.2	R661E	Pathogenic	0.553
BRCA1	P38398-1.2	R661F	Pathogenic	0.664
BRCA1	P38398-1.2	R661G	Pathogenic	0.908
BRCA1	P38398-1.2	R661H	Neutral	0.5
BRCA1	P38398-1.2	R661I	Pathogenic	0.716
BRCA1	P38398-1.2	R661K	Neutral	0.252
BRCA1	P38398-1.2	R661L	Pathogenic	0.637
BRCA1	P38398-1.2	R661M	Pathogenic	0.552
BRCA1	P38398-1.2	R661N	Pathogenic	0.623
BRCA1	P38398-1.2	R661P	Pathogenic	0.792
BRCA1	P38398-1.2	R661Q	Neutral	0.433
BRCA1	P38398-1.2	R661S	Pathogenic	0.797
BRCA1	P38398-1.2	R661T	Pathogenic	0.714
BRCA1	P38398-1.2	R661V	Pathogenic	0.795
BRCA1	P38398-1.2	R661W	Pathogenic	0.672
BRCA1	P38398-1.2	R661Y	Pathogenic	0.55
BRCA1	P38398-1.2	H662A	Neutral	0.363
BRCA1	P38398-1.2	H662C	Neutral	0.347
BRCA1	P38398-1.2	H662D	Neutral	0.186
BRCA1	P38398-1.2	H662E	Neutral	0.097
BRCA1	P38398-1.2	H662F	Neutral	0.153
BRCA1	P38398-1.2	H662G	Neutral	0.465
BRCA1	P38398-1.2	H662I	Neutral	0.227
BRCA1	P38398-1.2	H662K	Neutral	0.155
BRCA1	P38398-1.2	H662L	Neutral	0.227
BRCA1	P38398-1.2	H662M	Neutral	0.171
BRCA1	P38398-1.2	H662N	Neutral	0.09
BRCA1	P38398-1.2	H662P	Neutral	0.253
BRCA1	P38398-1.2	H662Q	Neutral	0.088
BRCA1	P38398-1.2	H662R	Neutral	0.145
BRCA1	P38398-1.2	H662S	Neutral	0.257
BRCA1	P38398-1.2	H662T	Neutral	0.243
BRCA1	P38398-1.2	H662V	Neutral	0.257
BRCA1	P38398-1.2	H662W	Neutral	0.325
BRCA1	P38398-1.2	H662Y	Neutral	0.066
BRCA1	P38398-1.2	S663A	Neutral	0.004
BRCA1	P38398-1.2	S663C	Neutral	0.01
BRCA1	P38398-1.2	S663D	Neutral	0.008
BRCA1	P38398-1.2	S663E	Neutral	0.012
BRCA1	P38398-1.2	S663F	Neutral	0.042
BRCA1	P38398-1.2	S663G	Neutral	0.009
BRCA1	P38398-1.2	S663H	Neutral	0.021
BRCA1	P38398-1.2	S663I	Neutral	0.033
BRCA1	P38398-1.2	S663K	Neutral	0.021
BRCA1	P38398-1.2	S663L	Neutral	0.033
BRCA1	P38398-1.2	S663M	Neutral	0.023
BRCA1	P38398-1.2	S663N	Neutral	0.006
BRCA1	P38398-1.2	S663P	Neutral	0.011
BRCA1	P38398-1.2	S663Q	Neutral	0.013
BRCA1	P38398-1.2	S663R	Neutral	0.039
BRCA1	P38398-1.2	S663T	Neutral	0.006
BRCA1	P38398-1.2	S663V	Neutral	0.022
BRCA1	P38398-1.2	S663W	Neutral	0.104
BRCA1	P38398-1.2	S663Y	Neutral	0.048
BRCA1	P38398-1.2	R664A	Neutral	0.432
BRCA1	P38398-1.2	R664C	Pathogenic	0.504
BRCA1	P38398-1.2	R664D	Neutral	0.396
BRCA1	P38398-1.2	R664E	Neutral	0.174
BRCA1	P38398-1.2	R664F	Neutral	0.252
BRCA1	P38398-1.2	R664G	Pathogenic	0.626
BRCA1	P38398-1.2	R664H	Neutral	0.146
BRCA1	P38398-1.2	R664I	Neutral	0.301
BRCA1	P38398-1.2	R664K	Neutral	0.055
BRCA1	P38398-1.2	R664L	Neutral	0.231
BRCA1	P38398-1.2	R664M	Neutral	0.174
BRCA1	P38398-1.2	R664N	Neutral	0.22
BRCA1	P38398-1.2	R664P	Neutral	0.394
BRCA1	P38398-1.2	R664Q	Neutral	0.115
BRCA1	P38398-1.2	R664S	Neutral	0.401
BRCA1	P38398-1.2	R664T	Neutral	0.299
BRCA1	P38398-1.2	R664V	Neutral	0.399
BRCA1	P38398-1.2	R664W	Neutral	0.259
BRCA1	P38398-1.2	R664Y	Neutral	0.173
BRCA1	P38398-1.2	N665A	Neutral	0.031
BRCA1	P38398-1.2	N665C	Neutral	0.029
BRCA1	P38398-1.2	N665D	Neutral	0.006
BRCA1	P38398-1.2	N665E	Neutral	0.011
BRCA1	P38398-1.2	N665F	Neutral	0.052
BRCA1	P38398-1.2	N665G	Neutral	0.023
BRCA1	P38398-1.2	N665H	Neutral	0.009
BRCA1	P38398-1.2	N665I	Neutral	0.041
BRCA1	P38398-1.2	N665K	Neutral	0.019
BRCA1	P38398-1.2	N665L	Neutral	0.042
BRCA1	P38398-1.2	N665M	Neutral	0.03
BRCA1	P38398-1.2	N665P	Neutral	0.018
BRCA1	P38398-1.2	N665Q	Neutral	0.012
BRCA1	P38398-1.2	N665R	Neutral	0.025
BRCA1	P38398-1.2	N665S	Neutral	0.009
BRCA1	P38398-1.2	N665T	Neutral	0.009
BRCA1	P38398-1.2	N665V	Neutral	0.028
BRCA1	P38398-1.2	N665W	Neutral	0.128
BRCA1	P38398-1.2	N665Y	Neutral	0.043
BRCA1	P38398-1.2	L666A	Pathogenic	0.713
BRCA1	P38398-1.2	L666C	Pathogenic	0.623
BRCA1	P38398-1.2	L666D	Pathogenic	0.81
BRCA1	P38398-1.2	L666E	Pathogenic	0.666
BRCA1	P38398-1.2	L666F	Neutral	0.39
BRCA1	P38398-1.2	L666G	Pathogenic	0.918
BRCA1	P38398-1.2	L666H	Pathogenic	0.623
BRCA1	P38398-1.2	L666I	Neutral	0.194
BRCA1	P38398-1.2	L666K	Pathogenic	0.557
BRCA1	P38398-1.2	L666M	Neutral	0.193
BRCA1	P38398-1.2	L666N	Pathogenic	0.727
BRCA1	P38398-1.2	L666P	Pathogenic	0.757
BRCA1	P38398-1.2	L666Q	Pathogenic	0.555
BRCA1	P38398-1.2	L666R	Pathogenic	0.627
BRCA1	P38398-1.2	L666S	Pathogenic	0.757
BRCA1	P38398-1.2	L666T	Pathogenic	0.583
BRCA1	P38398-1.2	L666V	Neutral	0.345
BRCA1	P38398-1.2	L666W	Pathogenic	0.709
BRCA1	P38398-1.2	L666Y	Pathogenic	0.509
BRCA1	P38398-1.2	Q667A	Neutral	0.483
BRCA1	P38398-1.2	Q667C	Pathogenic	0.556
BRCA1	P38398-1.2	Q667D	Neutral	0.276
BRCA1	P38398-1.2	Q667E	Neutral	0.11
BRCA1	P38398-1.2	Q667F	Pathogenic	0.514
BRCA1	P38398-1.2	Q667G	Pathogenic	0.674
BRCA1	P38398-1.2	Q667H	Neutral	0.201
BRCA1	P38398-1.2	Q667I	Neutral	0.453
BRCA1	P38398-1.2	Q667K	Neutral	0.201
BRCA1	P38398-1.2	Q667L	Neutral	0.366
BRCA1	P38398-1.2	Q667M	Neutral	0.219
BRCA1	P38398-1.2	Q667N	Neutral	0.255
BRCA1	P38398-1.2	Q667P	Neutral	0.358
BRCA1	P38398-1.2	Q667R	Neutral	0.252
BRCA1	P38398-1.2	Q667S	Neutral	0.364
BRCA1	P38398-1.2	Q667T	Neutral	0.344
BRCA1	P38398-1.2	Q667V	Neutral	0.363
BRCA1	P38398-1.2	Q667W	Pathogenic	0.575
BRCA1	P38398-1.2	Q667Y	Neutral	0.372
BRCA1	P38398-1.2	L668A	Pathogenic	0.646
BRCA1	P38398-1.2	L668C	Pathogenic	0.548
BRCA1	P38398-1.2	L668D	Pathogenic	0.758
BRCA1	P38398-1.2	L668E	Pathogenic	0.593
BRCA1	P38398-1.2	L668F	Neutral	0.319
BRCA1	P38398-1.2	L668G	Pathogenic	0.892
BRCA1	P38398-1.2	L668H	Pathogenic	0.548
BRCA1	P38398-1.2	L668I	Neutral	0.15
BRCA1	P38398-1.2	L668K	Neutral	0.48
BRCA1	P38398-1.2	L668M	Neutral	0.149
BRCA1	P38398-1.2	L668N	Pathogenic	0.661
BRCA1	P38398-1.2	L668P	Pathogenic	0.696
BRCA1	P38398-1.2	L668Q	Neutral	0.478
BRCA1	P38398-1.2	L668R	Pathogenic	0.552
BRCA1	P38398-1.2	L668S	Pathogenic	0.695
BRCA1	P38398-1.2	L668T	Pathogenic	0.506
BRCA1	P38398-1.2	L668V	Neutral	0.278
BRCA1	P38398-1.2	L668W	Pathogenic	0.641
BRCA1	P38398-1.2	L668Y	Neutral	0.432
BRCA1	P38398-1.2	M669A	Neutral	0.012
BRCA1	P38398-1.2	M669C	Neutral	0.008
BRCA1	P38398-1.2	M669D	Neutral	0.015
BRCA1	P38398-1.2	M669E	Neutral	0.007
BRCA1	P38398-1.2	M669F	Neutral	0.003
BRCA1	P38398-1.2	M669G	Neutral	0.038
BRCA1	P38398-1.2	M669H	Neutral	0.006
BRCA1	P38398-1.2	M669I	Neutral	0.002
BRCA1	P38398-1.2	M669K	Neutral	0.004
BRCA1	P38398-1.2	M669L	Neutral	0.001
BRCA1	P38398-1.2	M669N	Neutral	0.009
BRCA1	P38398-1.2	M669P	Neutral	0.011
BRCA1	P38398-1.2	M669Q	Neutral	0.003
BRCA1	P38398-1.2	M669R	Neutral	0.006
BRCA1	P38398-1.2	M669S	Neutral	0.011
BRCA1	P38398-1.2	M669T	Neutral	0.007
BRCA1	P38398-1.2	M669V	Neutral	0.003
BRCA1	P38398-1.2	M669W	Neutral	0.008
BRCA1	P38398-1.2	M669Y	Neutral	0.005
BRCA1	P38398-1.2	E670A	Neutral	0.075
BRCA1	P38398-1.2	E670C	Neutral	0.135
BRCA1	P38398-1.2	E670D	Neutral	0.016
BRCA1	P38398-1.2	E670F	Neutral	0.102
BRCA1	P38398-1.2	E670G	Neutral	0.151
BRCA1	P38398-1.2	E670H	Neutral	0.026
BRCA1	P38398-1.2	E670I	Neutral	0.082
BRCA1	P38398-1.2	E670K	Neutral	0.027
BRCA1	P38398-1.2	E670L	Neutral	0.082
BRCA1	P38398-1.2	E670M	Neutral	0.059
BRCA1	P38398-1.2	E670N	Neutral	0.029
BRCA1	P38398-1.2	E670P	Neutral	0.046
BRCA1	P38398-1.2	E670Q	Neutral	0.012
BRCA1	P38398-1.2	E670R	Neutral	0.05
BRCA1	P38398-1.2	E670S	Neutral	0.047
BRCA1	P38398-1.2	E670T	Neutral	0.043
BRCA1	P38398-1.2	E670V	Neutral	0.047
BRCA1	P38398-1.2	E670W	Neutral	0.174
BRCA1	P38398-1.2	E670Y	Neutral	0.084
BRCA1	P38398-1.2	G671A	Neutral	0.006
BRCA1	P38398-1.2	G671C	Neutral	0.027
BRCA1	P38398-1.2	G671D	Neutral	0.015
BRCA1	P38398-1.2	G671E	Neutral	0.032
BRCA1	P38398-1.2	G671F	Neutral	0.076
BRCA1	P38398-1.2	G671H	Neutral	0.039
BRCA1	P38398-1.2	G671I	Neutral	0.085
BRCA1	P38398-1.2	G671K	Neutral	0.055
BRCA1	P38398-1.2	G671L	Neutral	0.085
BRCA1	P38398-1.2	G671M	Neutral	0.061
BRCA1	P38398-1.2	G671N	Neutral	0.012
BRCA1	P38398-1.2	G671P	Neutral	0.021
BRCA1	P38398-1.2	G671Q	Neutral	0.036
BRCA1	P38398-1.2	G671R	Neutral	0.072
BRCA1	P38398-1.2	G671S	Neutral	0.007
BRCA1	P38398-1.2	G671T	Neutral	0.023
BRCA1	P38398-1.2	G671V	Neutral	0.041
BRCA1	P38398-1.2	G671W	Neutral	0.095
BRCA1	P38398-1.2	G671Y	Neutral	0.087
BRCA1	P38398-1.2	K672A	Neutral	0.018
BRCA1	P38398-1.2	K672C	Neutral	0.024
BRCA1	P38398-1.2	K672D	Neutral	0.011
BRCA1	P38398-1.2	K672E	Neutral	0.004
BRCA1	P38398-1.2	K672F	Neutral	0.008
BRCA1	P38398-1.2	K672G	Neutral	0.04
BRCA1	P38398-1.2	K672H	Neutral	0.006
BRCA1	P38398-1.2	K672I	Neutral	0.01
BRCA1	P38398-1.2	K672L	Neutral	0.007
BRCA1	P38398-1.2	K672M	Neutral	0.005
BRCA1	P38398-1.2	K672N	Neutral	0.007
BRCA1	P38398-1.2	K672P	Neutral	0.011
BRCA1	P38398-1.2	K672Q	Neutral	0.003
BRCA1	P38398-1.2	K672R	Neutral	0.002
BRCA1	P38398-1.2	K672S	Neutral	0.011
BRCA1	P38398-1.2	K672T	Neutral	0.01
BRCA1	P38398-1.2	K672V	Neutral	0.011
BRCA1	P38398-1.2	K672W	Neutral	0.015
BRCA1	P38398-1.2	K672Y	Neutral	0.007
BRCA1	P38398-1.2	E673A	Pathogenic	0.927
BRCA1	P38398-1.2	E673C	Pathogenic	0.961
BRCA1	P38398-1.2	E673D	Pathogenic	0.716
BRCA1	P38398-1.2	E673F	Pathogenic	0.947
BRCA1	P38398-1.2	E673G	Pathogenic	0.965
BRCA1	P38398-1.2	E673H	Pathogenic	0.809
BRCA1	P38398-1.2	E673I	Pathogenic	0.933
BRCA1	P38398-1.2	E673K	Pathogenic	0.812
BRCA1	P38398-1.2	E673L	Pathogenic	0.933
BRCA1	P38398-1.2	E673M	Pathogenic	0.907
BRCA1	P38398-1.2	E673N	Pathogenic	0.824
BRCA1	P38398-1.2	E673P	Pathogenic	0.883
BRCA1	P38398-1.2	E673Q	Pathogenic	0.653
BRCA1	P38398-1.2	E673R	Pathogenic	0.893
BRCA1	P38398-1.2	E673S	Pathogenic	0.886
BRCA1	P38398-1.2	E673T	Pathogenic	0.877
BRCA1	P38398-1.2	E673V	Pathogenic	0.885
BRCA1	P38398-1.2	E673W	Pathogenic	0.971
BRCA1	P38398-1.2	E673Y	Pathogenic	0.935
BRCA1	P38398-1.2	P674A	Neutral	0.013
BRCA1	P38398-1.2	P674C	Neutral	0.017
BRCA1	P38398-1.2	P674D	Neutral	0.008
BRCA1	P38398-1.2	P674E	Neutral	0.012
BRCA1	P38398-1.2	P674F	Neutral	0.059
BRCA1	P38398-1.2	P674G	Neutral	0.028
BRCA1	P38398-1.2	P674H	Neutral	0.021
BRCA1	P38398-1.2	P674I	Neutral	0.033
BRCA1	P38398-1.2	P674K	Neutral	0.02
BRCA1	P38398-1.2	P674L	Neutral	0.033
BRCA1	P38398-1.2	P674M	Neutral	0.023
BRCA1	P38398-1.2	P674N	Neutral	0.013
BRCA1	P38398-1.2	P674Q	Neutral	0.013
BRCA1	P38398-1.2	P674R	Neutral	0.038
BRCA1	P38398-1.2	P674S	Neutral	0.011
BRCA1	P38398-1.2	P674T	Neutral	0.008
BRCA1	P38398-1.2	P674V	Neutral	0.015
BRCA1	P38398-1.2	P674W	Neutral	0.104
BRCA1	P38398-1.2	P674Y	Neutral	0.048
BRCA1	P38398-1.2	A675C	Neutral	0.029
BRCA1	P38398-1.2	A675D	Neutral	0.064
BRCA1	P38398-1.2	A675E	Neutral	0.067
BRCA1	P38398-1.2	A675F	Neutral	0.153
BRCA1	P38398-1.2	A675G	Neutral	0.029
BRCA1	P38398-1.2	A675H	Neutral	0.113
BRCA1	P38398-1.2	A675I	Neutral	0.09
BRCA1	P38398-1.2	A675K	Neutral	0.112
BRCA1	P38398-1.2	A675L	Neutral	0.09
BRCA1	P38398-1.2	A675M	Neutral	0.091
BRCA1	P38398-1.2	A675N	Neutral	0.071
BRCA1	P38398-1.2	A675P	Neutral	0.045
BRCA1	P38398-1.2	A675Q	Neutral	0.074
BRCA1	P38398-1.2	A675R	Neutral	0.144
BRCA1	P38398-1.2	A675S	Neutral	0.015
BRCA1	P38398-1.2	A675T	Neutral	0.034
BRCA1	P38398-1.2	A675V	Neutral	0.043
BRCA1	P38398-1.2	A675W	Neutral	0.325
BRCA1	P38398-1.2	A675Y	Neutral	0.174
BRCA1	P38398-1.2	T676A	Neutral	0.029
BRCA1	P38398-1.2	T676C	Neutral	0.027
BRCA1	P38398-1.2	T676D	Neutral	0.024
BRCA1	P38398-1.2	T676E	Neutral	0.033
BRCA1	P38398-1.2	T676F	Neutral	0.08
BRCA1	P38398-1.2	T676G	Neutral	0.087
BRCA1	P38398-1.2	T676H	Neutral	0.058
BRCA1	P38398-1.2	T676I	Neutral	0.045
BRCA1	P38398-1.2	T676K	Neutral	0.057
BRCA1	P38398-1.2	T676L	Neutral	0.045
BRCA1	P38398-1.2	T676M	Neutral	0.046
BRCA1	P38398-1.2	T676N	Neutral	0.018
BRCA1	P38398-1.2	T676P	Neutral	0.025
BRCA1	P38398-1.2	T676Q	Neutral	0.037
BRCA1	P38398-1.2	T676R	Neutral	0.075
BRCA1	P38398-1.2	T676S	Neutral	0.018
BRCA1	P38398-1.2	T676V	Neutral	0.021
BRCA1	P38398-1.2	T676W	Neutral	0.138
BRCA1	P38398-1.2	T676Y	Neutral	0.092
BRCA1	P38398-1.2	G677A	Pathogenic	0.529
BRCA1	P38398-1.2	G677C	Pathogenic	0.834
BRCA1	P38398-1.2	G677D	Pathogenic	0.732
BRCA1	P38398-1.2	G677E	Pathogenic	0.855
BRCA1	P38398-1.2	G677F	Pathogenic	0.936
BRCA1	P38398-1.2	G677H	Pathogenic	0.879
BRCA1	P38398-1.2	G677I	Pathogenic	0.943
BRCA1	P38398-1.2	G677K	Pathogenic	0.912
BRCA1	P38398-1.2	G677L	Pathogenic	0.943
BRCA1	P38398-1.2	G677M	Pathogenic	0.921
BRCA1	P38398-1.2	G677N	Pathogenic	0.68
BRCA1	P38398-1.2	G677P	Pathogenic	0.794
BRCA1	P38398-1.2	G677Q	Pathogenic	0.869
BRCA1	P38398-1.2	G677R	Pathogenic	0.933
BRCA1	P38398-1.2	G677S	Pathogenic	0.563
BRCA1	P38398-1.2	G677T	Pathogenic	0.806
BRCA1	P38398-1.2	G677V	Pathogenic	0.884
BRCA1	P38398-1.2	G677W	Pathogenic	0.95
BRCA1	P38398-1.2	G677Y	Pathogenic	0.945
BRCA1	P38398-1.2	A678C	Neutral	0.097
BRCA1	P38398-1.2	A678D	Neutral	0.197
BRCA1	P38398-1.2	A678E	Neutral	0.203
BRCA1	P38398-1.2	A678F	Neutral	0.393
BRCA1	P38398-1.2	A678G	Neutral	0.097
BRCA1	P38398-1.2	A678H	Neutral	0.313
BRCA1	P38398-1.2	A678I	Neutral	0.261
BRCA1	P38398-1.2	A678K	Neutral	0.311
BRCA1	P38398-1.2	A678L	Neutral	0.261
BRCA1	P38398-1.2	A678M	Neutral	0.263
BRCA1	P38398-1.2	A678N	Neutral	0.216
BRCA1	P38398-1.2	A678P	Neutral	0.145
BRCA1	P38398-1.2	A678Q	Neutral	0.223
BRCA1	P38398-1.2	A678R	Neutral	0.376
BRCA1	P38398-1.2	A678S	Neutral	0.053
BRCA1	P38398-1.2	A678T	Neutral	0.112
BRCA1	P38398-1.2	A678V	Neutral	0.14
BRCA1	P38398-1.2	A678W	Pathogenic	0.633
BRCA1	P38398-1.2	A678Y	Neutral	0.429
BRCA1	P38398-1.2	K679A	Pathogenic	0.742
BRCA1	P38398-1.2	K679C	Pathogenic	0.794
BRCA1	P38398-1.2	K679D	Pathogenic	0.633
BRCA1	P38398-1.2	K679E	Neutral	0.358
BRCA1	P38398-1.2	K679F	Pathogenic	0.562
BRCA1	P38398-1.2	K679G	Pathogenic	0.864
BRCA1	P38398-1.2	K679H	Neutral	0.482
BRCA1	P38398-1.2	K679I	Pathogenic	0.62
BRCA1	P38398-1.2	K679L	Pathogenic	0.532
BRCA1	P38398-1.2	K679M	Neutral	0.444
BRCA1	P38398-1.2	K679N	Pathogenic	0.517
BRCA1	P38398-1.2	K679P	Pathogenic	0.632
BRCA1	P38398-1.2	K679Q	Neutral	0.331
BRCA1	P38398-1.2	K679R	Neutral	0.226
BRCA1	P38398-1.2	K679S	Pathogenic	0.638
BRCA1	P38398-1.2	K679T	Pathogenic	0.618
BRCA1	P38398-1.2	K679V	Pathogenic	0.637
BRCA1	P38398-1.2	K679W	Pathogenic	0.703
BRCA1	P38398-1.2	K679Y	Pathogenic	0.508
BRCA1	P38398-1.2	K680A	Pathogenic	0.853
BRCA1	P38398-1.2	K680C	Pathogenic	0.886
BRCA1	P38398-1.2	K680D	Pathogenic	0.777
BRCA1	P38398-1.2	K680E	Pathogenic	0.529
BRCA1	P38398-1.2	K680F	Pathogenic	0.721
BRCA1	P38398-1.2	K680G	Pathogenic	0.928
BRCA1	P38398-1.2	K680H	Pathogenic	0.652
BRCA1	P38398-1.2	K680I	Pathogenic	0.767
BRCA1	P38398-1.2	K680L	Pathogenic	0.696
BRCA1	P38398-1.2	K680M	Pathogenic	0.617
BRCA1	P38398-1.2	K680N	Pathogenic	0.683
BRCA1	P38398-1.2	K680P	Pathogenic	0.776
BRCA1	P38398-1.2	K680Q	Neutral	0.499
BRCA1	P38398-1.2	K680R	Neutral	0.37
BRCA1	P38398-1.2	K680S	Pathogenic	0.78
BRCA1	P38398-1.2	K680T	Pathogenic	0.765
BRCA1	P38398-1.2	K680V	Pathogenic	0.779
BRCA1	P38398-1.2	K680W	Pathogenic	0.826
BRCA1	P38398-1.2	K680Y	Pathogenic	0.675
BRCA1	P38398-1.2	S681A	Neutral	0.027
BRCA1	P38398-1.2	S681C	Neutral	0.063
BRCA1	P38398-1.2	S681D	Neutral	0.05
BRCA1	P38398-1.2	S681E	Neutral	0.073
BRCA1	P38398-1.2	S681F	Neutral	0.22
BRCA1	P38398-1.2	S681G	Neutral	0.058
BRCA1	P38398-1.2	S681H	Neutral	0.122
BRCA1	P38398-1.2	S681I	Neutral	0.181
BRCA1	P38398-1.2	S681K	Neutral	0.122
BRCA1	P38398-1.2	S681L	Neutral	0.182
BRCA1	P38398-1.2	S681M	Neutral	0.135
BRCA1	P38398-1.2	S681N	Neutral	0.039
BRCA1	P38398-1.2	S681P	Neutral	0.069
BRCA1	P38398-1.2	S681Q	Neutral	0.081
BRCA1	P38398-1.2	S681R	Neutral	0.211
BRCA1	P38398-1.2	S681T	Neutral	0.037
BRCA1	P38398-1.2	S681V	Neutral	0.128
BRCA1	P38398-1.2	S681W	Neutral	0.429
BRCA1	P38398-1.2	S681Y	Neutral	0.247
BRCA1	P38398-1.2	N682A	Neutral	0.175
BRCA1	P38398-1.2	N682C	Neutral	0.165
BRCA1	P38398-1.2	N682D	Neutral	0.041
BRCA1	P38398-1.2	N682E	Neutral	0.068
BRCA1	P38398-1.2	N682F	Neutral	0.27
BRCA1	P38398-1.2	N682G	Neutral	0.136
BRCA1	P38398-1.2	N682H	Neutral	0.058
BRCA1	P38398-1.2	N682I	Neutral	0.225
BRCA1	P38398-1.2	N682K	Neutral	0.114
BRCA1	P38398-1.2	N682L	Neutral	0.225
BRCA1	P38398-1.2	N682M	Neutral	0.169
BRCA1	P38398-1.2	N682P	Neutral	0.112
BRCA1	P38398-1.2	N682Q	Neutral	0.075
BRCA1	P38398-1.2	N682R	Neutral	0.147
BRCA1	P38398-1.2	N682S	Neutral	0.059
BRCA1	P38398-1.2	N682T	Neutral	0.054
BRCA1	P38398-1.2	N682V	Neutral	0.161
BRCA1	P38398-1.2	N682W	Neutral	0.496
BRCA1	P38398-1.2	N682Y	Neutral	0.23
BRCA1	P38398-1.2	K683A	Pathogenic	0.693
BRCA1	P38398-1.2	K683C	Pathogenic	0.751
BRCA1	P38398-1.2	K683D	Pathogenic	0.575
BRCA1	P38398-1.2	K683E	Neutral	0.304
BRCA1	P38398-1.2	K683F	Pathogenic	0.501
BRCA1	P38398-1.2	K683G	Pathogenic	0.833
BRCA1	P38398-1.2	K683H	Neutral	0.422
BRCA1	P38398-1.2	K683I	Pathogenic	0.561
BRCA1	P38398-1.2	K683L	Neutral	0.471
BRCA1	P38398-1.2	K683M	Neutral	0.384
BRCA1	P38398-1.2	K683N	Neutral	0.456
BRCA1	P38398-1.2	K683P	Pathogenic	0.573
BRCA1	P38398-1.2	K683Q	Neutral	0.279
BRCA1	P38398-1.2	K683R	Neutral	0.186
BRCA1	P38398-1.2	K683S	Pathogenic	0.58
BRCA1	P38398-1.2	K683T	Pathogenic	0.559
BRCA1	P38398-1.2	K683V	Pathogenic	0.578
BRCA1	P38398-1.2	K683W	Pathogenic	0.649
BRCA1	P38398-1.2	K683Y	Neutral	0.447
BRCA1	P38398-1.2	P684A	Neutral	0.456
BRCA1	P38398-1.2	P684C	Pathogenic	0.533
BRCA1	P38398-1.2	P684D	Neutral	0.335
BRCA1	P38398-1.2	P684E	Neutral	0.43
BRCA1	P38398-1.2	P684F	Pathogenic	0.801
BRCA1	P38398-1.2	P684G	Pathogenic	0.647
BRCA1	P38398-1.2	P684H	Pathogenic	0.574
BRCA1	P38398-1.2	P684I	Pathogenic	0.687
BRCA1	P38398-1.2	P684K	Pathogenic	0.572
BRCA1	P38398-1.2	P684L	Pathogenic	0.687
BRCA1	P38398-1.2	P684M	Pathogenic	0.606
BRCA1	P38398-1.2	P684N	Neutral	0.449
BRCA1	P38398-1.2	P684Q	Neutral	0.459
BRCA1	P38398-1.2	P684R	Pathogenic	0.719
BRCA1	P38398-1.2	P684S	Neutral	0.422
BRCA1	P38398-1.2	P684T	Neutral	0.35
BRCA1	P38398-1.2	P684V	Pathogenic	0.502
BRCA1	P38398-1.2	P684W	Pathogenic	0.881
BRCA1	P38398-1.2	P684Y	Pathogenic	0.765
BRCA1	P38398-1.2	N685A	Neutral	0.005
BRCA1	P38398-1.2	N685C	Neutral	0.005
BRCA1	P38398-1.2	N685D	Neutral	0.001
BRCA1	P38398-1.2	N685E	Neutral	0.002
BRCA1	P38398-1.2	N685F	Neutral	0.009
BRCA1	P38398-1.2	N685G	Neutral	0.004
BRCA1	P38398-1.2	N685H	Neutral	0.001
BRCA1	P38398-1.2	N685I	Neutral	0.007
BRCA1	P38398-1.2	N685K	Neutral	0.003
BRCA1	P38398-1.2	N685L	Neutral	0.007
BRCA1	P38398-1.2	N685M	Neutral	0.005
BRCA1	P38398-1.2	N685P	Neutral	0.003
BRCA1	P38398-1.2	N685Q	Neutral	0.002
BRCA1	P38398-1.2	N685R	Neutral	0.004
BRCA1	P38398-1.2	N685S	Neutral	0.001
BRCA1	P38398-1.2	N685T	Neutral	0.001
BRCA1	P38398-1.2	N685V	Neutral	0.004
BRCA1	P38398-1.2	N685W	Neutral	0.022
BRCA1	P38398-1.2	N685Y	Neutral	0.007
BRCA1	P38398-1.2	E686A	Pathogenic	0.769
BRCA1	P38398-1.2	E686C	Pathogenic	0.865
BRCA1	P38398-1.2	E686D	Neutral	0.4
BRCA1	P38398-1.2	E686F	Pathogenic	0.824
BRCA1	P38398-1.2	E686G	Pathogenic	0.88
BRCA1	P38398-1.2	E686H	Pathogenic	0.527
BRCA1	P38398-1.2	E686I	Pathogenic	0.786
BRCA1	P38398-1.2	E686K	Pathogenic	0.533
BRCA1	P38398-1.2	E686L	Pathogenic	0.787
BRCA1	P38398-1.2	E686M	Pathogenic	0.721
BRCA1	P38398-1.2	E686N	Pathogenic	0.553
BRCA1	P38398-1.2	E686P	Pathogenic	0.665
BRCA1	P38398-1.2	E686Q	Neutral	0.332
BRCA1	P38398-1.2	E686R	Pathogenic	0.686
BRCA1	P38398-1.2	E686S	Pathogenic	0.671
BRCA1	P38398-1.2	E686T	Pathogenic	0.652
BRCA1	P38398-1.2	E686V	Pathogenic	0.669
BRCA1	P38398-1.2	E686W	Pathogenic	0.897
BRCA1	P38398-1.2	E686Y	Pathogenic	0.791
BRCA1	P38398-1.2	Q687A	Pathogenic	0.741
BRCA1	P38398-1.2	Q687C	Pathogenic	0.793
BRCA1	P38398-1.2	Q687D	Pathogenic	0.539
BRCA1	P38398-1.2	Q687E	Neutral	0.275
BRCA1	P38398-1.2	Q687F	Pathogenic	0.764
BRCA1	P38398-1.2	Q687G	Pathogenic	0.863
BRCA1	P38398-1.2	Q687H	Neutral	0.435
BRCA1	P38398-1.2	Q687I	Pathogenic	0.717
BRCA1	P38398-1.2	Q687K	Neutral	0.436
BRCA1	P38398-1.2	Q687L	Pathogenic	0.638
BRCA1	P38398-1.2	Q687M	Neutral	0.462
BRCA1	P38398-1.2	Q687N	Pathogenic	0.512
BRCA1	P38398-1.2	Q687P	Pathogenic	0.63
BRCA1	P38398-1.2	Q687R	Pathogenic	0.508
BRCA1	P38398-1.2	Q687S	Pathogenic	0.637
BRCA1	P38398-1.2	Q687T	Pathogenic	0.617
BRCA1	P38398-1.2	Q687V	Pathogenic	0.635
BRCA1	P38398-1.2	Q687W	Pathogenic	0.806
BRCA1	P38398-1.2	Q687Y	Pathogenic	0.645
BRCA1	P38398-1.2	T688A	Neutral	0.015
BRCA1	P38398-1.2	T688C	Neutral	0.014
BRCA1	P38398-1.2	T688D	Neutral	0.012
BRCA1	P38398-1.2	T688E	Neutral	0.017
BRCA1	P38398-1.2	T688F	Neutral	0.041
BRCA1	P38398-1.2	T688G	Neutral	0.045
BRCA1	P38398-1.2	T688H	Neutral	0.029
BRCA1	P38398-1.2	T688I	Neutral	0.023
BRCA1	P38398-1.2	T688K	Neutral	0.029
BRCA1	P38398-1.2	T688L	Neutral	0.023
BRCA1	P38398-1.2	T688M	Neutral	0.023
BRCA1	P38398-1.2	T688N	Neutral	0.009
BRCA1	P38398-1.2	T688P	Neutral	0.013
BRCA1	P38398-1.2	T688Q	Neutral	0.019
BRCA1	P38398-1.2	T688R	Neutral	0.038
BRCA1	P38398-1.2	T688S	Neutral	0.009
BRCA1	P38398-1.2	T688V	Neutral	0.011
BRCA1	P38398-1.2	T688W	Neutral	0.073
BRCA1	P38398-1.2	T688Y	Neutral	0.047
BRCA1	P38398-1.2	S689A	Neutral	0.002
BRCA1	P38398-1.2	S689C	Neutral	0.004
BRCA1	P38398-1.2	S689D	Neutral	0.003
BRCA1	P38398-1.2	S689E	Neutral	0.005
BRCA1	P38398-1.2	S689F	Neutral	0.017
BRCA1	P38398-1.2	S689G	Neutral	0.004
BRCA1	P38398-1.2	S689H	Neutral	0.008
BRCA1	P38398-1.2	S689I	Neutral	0.013
BRCA1	P38398-1.2	S689K	Neutral	0.008
BRCA1	P38398-1.2	S689L	Neutral	0.013
BRCA1	P38398-1.2	S689M	Neutral	0.009
BRCA1	P38398-1.2	S689N	Neutral	0.003
BRCA1	P38398-1.2	S689P	Neutral	0.005
BRCA1	P38398-1.2	S689Q	Neutral	0.005
BRCA1	P38398-1.2	S689R	Neutral	0.016
BRCA1	P38398-1.2	S689T	Neutral	0.002
BRCA1	P38398-1.2	S689V	Neutral	0.009
BRCA1	P38398-1.2	S689W	Neutral	0.044
BRCA1	P38398-1.2	S689Y	Neutral	0.02
BRCA1	P38398-1.2	K690A	Pathogenic	0.817
BRCA1	P38398-1.2	K690C	Pathogenic	0.857
BRCA1	P38398-1.2	K690D	Pathogenic	0.728
BRCA1	P38398-1.2	K690E	Neutral	0.464
BRCA1	P38398-1.2	K690F	Pathogenic	0.665
BRCA1	P38398-1.2	K690G	Pathogenic	0.908
BRCA1	P38398-1.2	K690H	Pathogenic	0.591
BRCA1	P38398-1.2	K690I	Pathogenic	0.717
BRCA1	P38398-1.2	K690L	Pathogenic	0.638
BRCA1	P38398-1.2	K690M	Pathogenic	0.553
BRCA1	P38398-1.2	K690N	Pathogenic	0.624
BRCA1	P38398-1.2	K690P	Pathogenic	0.727
BRCA1	P38398-1.2	K690Q	Neutral	0.434
BRCA1	P38398-1.2	K690R	Neutral	0.312
BRCA1	P38398-1.2	K690S	Pathogenic	0.732
BRCA1	P38398-1.2	K690T	Pathogenic	0.715
BRCA1	P38398-1.2	K690V	Pathogenic	0.731
BRCA1	P38398-1.2	K690W	Pathogenic	0.786
BRCA1	P38398-1.2	K690Y	Pathogenic	0.616
BRCA1	P38398-1.2	R691A	Pathogenic	0.905
BRCA1	P38398-1.2	R691C	Pathogenic	0.927
BRCA1	P38398-1.2	R691D	Pathogenic	0.891
BRCA1	P38398-1.2	R691E	Pathogenic	0.726
BRCA1	P38398-1.2	R691F	Pathogenic	0.809
BRCA1	P38398-1.2	R691G	Pathogenic	0.955
BRCA1	P38398-1.2	R691H	Pathogenic	0.681
BRCA1	P38398-1.2	R691I	Pathogenic	0.844
BRCA1	P38398-1.2	R691K	Neutral	0.419
BRCA1	P38398-1.2	R691L	Pathogenic	0.79
BRCA1	P38398-1.2	R691M	Pathogenic	0.725
BRCA1	P38398-1.2	R691N	Pathogenic	0.779
BRCA1	P38398-1.2	R691P	Pathogenic	0.891
BRCA1	P38398-1.2	R691Q	Pathogenic	0.62
BRCA1	P38398-1.2	R691S	Pathogenic	0.893
BRCA1	P38398-1.2	R691T	Pathogenic	0.842
BRCA1	P38398-1.2	R691V	Pathogenic	0.893
BRCA1	P38398-1.2	R691W	Pathogenic	0.814
BRCA1	P38398-1.2	R691Y	Pathogenic	0.723
BRCA1	P38398-1.2	H692A	Neutral	0.006
BRCA1	P38398-1.2	H692C	Neutral	0.005
BRCA1	P38398-1.2	H692D	Neutral	0.002
BRCA1	P38398-1.2	H692E	Neutral	0.001
BRCA1	P38398-1.2	H692F	Neutral	0.002
BRCA1	P38398-1.2	H692G	Neutral	0.009
BRCA1	P38398-1.2	H692I	Neutral	0.003
BRCA1	P38398-1.2	H692K	Neutral	0.002
BRCA1	P38398-1.2	H692L	Neutral	0.003
BRCA1	P38398-1.2	H692M	Neutral	0.002
BRCA1	P38398-1.2	H692N	Neutral	0.001
BRCA1	P38398-1.2	H692P	Neutral	0.003
BRCA1	P38398-1.2	H692Q	Neutral	0.001
BRCA1	P38398-1.2	H692R	Neutral	0.002
BRCA1	P38398-1.2	H692S	Neutral	0.003
BRCA1	P38398-1.2	H692T	Neutral	0.003
BRCA1	P38398-1.2	H692V	Neutral	0.003
BRCA1	P38398-1.2	H692W	Neutral	0.005
BRCA1	P38398-1.2	H692Y	Neutral	0.001
BRCA1	P38398-1.2	D693A	Neutral	0.092
BRCA1	P38398-1.2	D693C	Neutral	0.086
BRCA1	P38398-1.2	D693E	Neutral	0.021
BRCA1	P38398-1.2	D693F	Neutral	0.18
BRCA1	P38398-1.2	D693G	Neutral	0.097
BRCA1	P38398-1.2	D693H	Neutral	0.07
BRCA1	P38398-1.2	D693I	Neutral	0.147
BRCA1	P38398-1.2	D693K	Neutral	0.1
BRCA1	P38398-1.2	D693L	Neutral	0.199
BRCA1	P38398-1.2	D693M	Neutral	0.148
BRCA1	P38398-1.2	D693N	Neutral	0.022
BRCA1	P38398-1.2	D693P	Neutral	0.04
BRCA1	P38398-1.2	D693Q	Neutral	0.046
BRCA1	P38398-1.2	D693R	Neutral	0.176
BRCA1	P38398-1.2	D693S	Neutral	0.041
BRCA1	P38398-1.2	D693T	Neutral	0.041
BRCA1	P38398-1.2	D693V	Neutral	0.102
BRCA1	P38398-1.2	D693W	Neutral	0.369
BRCA1	P38398-1.2	D693Y	Neutral	0.203
BRCA1	P38398-1.2	S694A	Neutral	0.014
BRCA1	P38398-1.2	S694C	Neutral	0.032
BRCA1	P38398-1.2	S694D	Neutral	0.025
BRCA1	P38398-1.2	S694E	Neutral	0.038
BRCA1	P38398-1.2	S694F	Neutral	0.123
BRCA1	P38398-1.2	S694G	Neutral	0.03
BRCA1	P38398-1.2	S694H	Neutral	0.065
BRCA1	P38398-1.2	S694I	Neutral	0.099
BRCA1	P38398-1.2	S694K	Neutral	0.065
BRCA1	P38398-1.2	S694L	Neutral	0.099
BRCA1	P38398-1.2	S694M	Neutral	0.072
BRCA1	P38398-1.2	S694N	Neutral	0.02
BRCA1	P38398-1.2	S694P	Neutral	0.035
BRCA1	P38398-1.2	S694Q	Neutral	0.042
BRCA1	P38398-1.2	S694R	Neutral	0.117
BRCA1	P38398-1.2	S694T	Neutral	0.019
BRCA1	P38398-1.2	S694V	Neutral	0.068
BRCA1	P38398-1.2	S694W	Neutral	0.272
BRCA1	P38398-1.2	S694Y	Neutral	0.14
BRCA1	P38398-1.2	D695A	Neutral	0.137
BRCA1	P38398-1.2	D695C	Neutral	0.129
BRCA1	P38398-1.2	D695E	Neutral	0.032
BRCA1	P38398-1.2	D695F	Neutral	0.257
BRCA1	P38398-1.2	D695G	Neutral	0.144
BRCA1	P38398-1.2	D695H	Neutral	0.106
BRCA1	P38398-1.2	D695I	Neutral	0.213
BRCA1	P38398-1.2	D695K	Neutral	0.149
BRCA1	P38398-1.2	D695L	Neutral	0.281
BRCA1	P38398-1.2	D695M	Neutral	0.215
BRCA1	P38398-1.2	D695N	Neutral	0.034
BRCA1	P38398-1.2	D695P	Neutral	0.061
BRCA1	P38398-1.2	D695Q	Neutral	0.07
BRCA1	P38398-1.2	D695R	Neutral	0.251
BRCA1	P38398-1.2	D695S	Neutral	0.063
BRCA1	P38398-1.2	D695T	Neutral	0.063
BRCA1	P38398-1.2	D695V	Neutral	0.152
BRCA1	P38398-1.2	D695W	Neutral	0.479
BRCA1	P38398-1.2	D695Y	Neutral	0.286
BRCA1	P38398-1.2	T696A	Neutral	0.039
BRCA1	P38398-1.2	T696C	Neutral	0.036
BRCA1	P38398-1.2	T696D	Neutral	0.032
BRCA1	P38398-1.2	T696E	Neutral	0.043
BRCA1	P38398-1.2	T696F	Neutral	0.103
BRCA1	P38398-1.2	T696G	Neutral	0.112
BRCA1	P38398-1.2	T696H	Neutral	0.075
BRCA1	P38398-1.2	T696I	Neutral	0.059
BRCA1	P38398-1.2	T696K	Neutral	0.074
BRCA1	P38398-1.2	T696L	Neutral	0.059
BRCA1	P38398-1.2	T696M	Neutral	0.06
BRCA1	P38398-1.2	T696N	Neutral	0.023
BRCA1	P38398-1.2	T696P	Neutral	0.033
BRCA1	P38398-1.2	T696Q	Neutral	0.049
BRCA1	P38398-1.2	T696R	Neutral	0.097
BRCA1	P38398-1.2	T696S	Neutral	0.024
BRCA1	P38398-1.2	T696V	Neutral	0.028
BRCA1	P38398-1.2	T696W	Neutral	0.175
BRCA1	P38398-1.2	T696Y	Neutral	0.118
BRCA1	P38398-1.2	F697A	Neutral	0.31
BRCA1	P38398-1.2	F697C	Neutral	0.23
BRCA1	P38398-1.2	F697D	Neutral	0.271
BRCA1	P38398-1.2	F697E	Neutral	0.2
BRCA1	P38398-1.2	F697G	Neutral	0.495
BRCA1	P38398-1.2	F697H	Neutral	0.091
BRCA1	P38398-1.2	F697I	Neutral	0.059
BRCA1	P38398-1.2	F697K	Neutral	0.122
BRCA1	P38398-1.2	F697L	Neutral	0.059
BRCA1	P38398-1.2	F697M	Neutral	0.059
BRCA1	P38398-1.2	F697N	Neutral	0.25
BRCA1	P38398-1.2	F697P	Neutral	0.36
BRCA1	P38398-1.2	F697Q	Neutral	0.184
BRCA1	P38398-1.2	F697R	Neutral	0.157
BRCA1	P38398-1.2	F697S	Neutral	0.281
BRCA1	P38398-1.2	F697T	Neutral	0.201
BRCA1	P38398-1.2	F697V	Neutral	0.12
BRCA1	P38398-1.2	F697W	Neutral	0.059
BRCA1	P38398-1.2	F697Y	Neutral	0.018
BRCA1	P38398-1.2	P698A	Pathogenic	0.838
BRCA1	P38398-1.2	P698C	Pathogenic	0.875
BRCA1	P38398-1.2	P698D	Pathogenic	0.756
BRCA1	P38398-1.2	P698E	Pathogenic	0.823
BRCA1	P38398-1.2	P698F	Pathogenic	0.961
BRCA1	P38398-1.2	P698G	Pathogenic	0.918
BRCA1	P38398-1.2	P698H	Pathogenic	0.892
BRCA1	P38398-1.2	P698I	Pathogenic	0.931
BRCA1	P38398-1.2	P698K	Pathogenic	0.891
BRCA1	P38398-1.2	P698L	Pathogenic	0.931
BRCA1	P38398-1.2	P698M	Pathogenic	0.904
BRCA1	P38398-1.2	P698N	Pathogenic	0.833
BRCA1	P38398-1.2	P698Q	Pathogenic	0.839
BRCA1	P38398-1.2	P698R	Pathogenic	0.94
BRCA1	P38398-1.2	P698S	Pathogenic	0.818
BRCA1	P38398-1.2	P698T	Pathogenic	0.768
BRCA1	P38398-1.2	P698V	Pathogenic	0.861
BRCA1	P38398-1.2	P698W	Pathogenic	0.979
BRCA1	P38398-1.2	P698Y	Pathogenic	0.952
BRCA1	P38398-1.2	E699A	Neutral	0.473
BRCA1	P38398-1.2	E699C	Pathogenic	0.634
BRCA1	P38398-1.2	E699D	Neutral	0.152
BRCA1	P38398-1.2	E699F	Pathogenic	0.558
BRCA1	P38398-1.2	E699G	Pathogenic	0.664
BRCA1	P38398-1.2	E699H	Neutral	0.231
BRCA1	P38398-1.2	E699I	Neutral	0.498
BRCA1	P38398-1.2	E699K	Neutral	0.235
BRCA1	P38398-1.2	E699L	Neutral	0.498
BRCA1	P38398-1.2	E699M	Neutral	0.41
BRCA1	P38398-1.2	E699N	Neutral	0.25
BRCA1	P38398-1.2	E699P	Neutral	0.348
BRCA1	P38398-1.2	E699Q	Neutral	0.118
BRCA1	P38398-1.2	E699R	Neutral	0.371
BRCA1	P38398-1.2	E699S	Neutral	0.354
BRCA1	P38398-1.2	E699T	Neutral	0.335
BRCA1	P38398-1.2	E699V	Neutral	0.353
BRCA1	P38398-1.2	E699W	Pathogenic	0.7
BRCA1	P38398-1.2	E699Y	Pathogenic	0.505
BRCA1	P38398-1.2	L700A	Neutral	0.1
BRCA1	P38398-1.2	L700C	Neutral	0.068
BRCA1	P38398-1.2	L700D	Neutral	0.159
BRCA1	P38398-1.2	L700E	Neutral	0.081
BRCA1	P38398-1.2	L700F	Neutral	0.028
BRCA1	P38398-1.2	L700G	Neutral	0.333
BRCA1	P38398-1.2	L700H	Neutral	0.068
BRCA1	P38398-1.2	L700I	Neutral	0.011
BRCA1	P38398-1.2	L700K	Neutral	0.053
BRCA1	P38398-1.2	L700M	Neutral	0.011
BRCA1	P38398-1.2	L700N	Neutral	0.106
BRCA1	P38398-1.2	L700P	Neutral	0.122
BRCA1	P38398-1.2	L700Q	Neutral	0.053
BRCA1	P38398-1.2	L700R	Neutral	0.069
BRCA1	P38398-1.2	L700S	Neutral	0.122
BRCA1	P38398-1.2	L700T	Neutral	0.058
BRCA1	P38398-1.2	L700V	Neutral	0.023
BRCA1	P38398-1.2	L700W	Neutral	0.098
BRCA1	P38398-1.2	L700Y	Neutral	0.044
BRCA1	P38398-1.2	K701A	Neutral	0.038
BRCA1	P38398-1.2	K701C	Neutral	0.051
BRCA1	P38398-1.2	K701D	Neutral	0.023
BRCA1	P38398-1.2	K701E	Neutral	0.008
BRCA1	P38398-1.2	K701F	Neutral	0.017
BRCA1	P38398-1.2	K701G	Neutral	0.081
BRCA1	P38398-1.2	K701H	Neutral	0.013
BRCA1	P38398-1.2	K701I	Neutral	0.022
BRCA1	P38398-1.2	K701L	Neutral	0.015
BRCA1	P38398-1.2	K701M	Neutral	0.011
BRCA1	P38398-1.2	K701N	Neutral	0.015
BRCA1	P38398-1.2	K701P	Neutral	0.023
BRCA1	P38398-1.2	K701Q	Neutral	0.007
BRCA1	P38398-1.2	K701R	Neutral	0.004
BRCA1	P38398-1.2	K701S	Neutral	0.024
BRCA1	P38398-1.2	K701T	Neutral	0.022
BRCA1	P38398-1.2	K701V	Neutral	0.024
BRCA1	P38398-1.2	K701W	Neutral	0.032
BRCA1	P38398-1.2	K701Y	Neutral	0.014
BRCA1	P38398-1.2	L702A	Pathogenic	0.536
BRCA1	P38398-1.2	L702C	Neutral	0.434
BRCA1	P38398-1.2	L702D	Pathogenic	0.664
BRCA1	P38398-1.2	L702E	Neutral	0.48
BRCA1	P38398-1.2	L702F	Neutral	0.229
BRCA1	P38398-1.2	L702G	Pathogenic	0.839
BRCA1	P38398-1.2	L702H	Neutral	0.434
BRCA1	P38398-1.2	L702I	Neutral	0.101
BRCA1	P38398-1.2	L702K	Neutral	0.369
BRCA1	P38398-1.2	L702M	Neutral	0.1
BRCA1	P38398-1.2	L702N	Pathogenic	0.552
BRCA1	P38398-1.2	L702P	Pathogenic	0.591
BRCA1	P38398-1.2	L702Q	Neutral	0.367
BRCA1	P38398-1.2	L702R	Neutral	0.438
BRCA1	P38398-1.2	L702S	Pathogenic	0.591
BRCA1	P38398-1.2	L702T	Neutral	0.393
BRCA1	P38398-1.2	L702V	Neutral	0.196
BRCA1	P38398-1.2	L702W	Pathogenic	0.531
BRCA1	P38398-1.2	L702Y	Neutral	0.325
BRCA1	P38398-1.2	T703A	Neutral	0.187
BRCA1	P38398-1.2	T703C	Neutral	0.177
BRCA1	P38398-1.2	T703D	Neutral	0.16
BRCA1	P38398-1.2	T703E	Neutral	0.207
BRCA1	P38398-1.2	T703F	Neutral	0.398
BRCA1	P38398-1.2	T703G	Neutral	0.42
BRCA1	P38398-1.2	T703H	Neutral	0.318
BRCA1	P38398-1.2	T703I	Neutral	0.265
BRCA1	P38398-1.2	T703K	Neutral	0.316
BRCA1	P38398-1.2	T703L	Neutral	0.265
BRCA1	P38398-1.2	T703M	Neutral	0.267
BRCA1	P38398-1.2	T703N	Neutral	0.12
BRCA1	P38398-1.2	T703P	Neutral	0.165
BRCA1	P38398-1.2	T703Q	Neutral	0.227
BRCA1	P38398-1.2	T703R	Neutral	0.382
BRCA1	P38398-1.2	T703S	Neutral	0.122
BRCA1	P38398-1.2	T703V	Neutral	0.142
BRCA1	P38398-1.2	T703W	Pathogenic	0.55
BRCA1	P38398-1.2	T703Y	Neutral	0.434
BRCA1	P38398-1.2	N704A	Neutral	0.279
BRCA1	P38398-1.2	N704C	Neutral	0.265
BRCA1	P38398-1.2	N704D	Neutral	0.072
BRCA1	P38398-1.2	N704E	Neutral	0.118
BRCA1	P38398-1.2	N704F	Neutral	0.403
BRCA1	P38398-1.2	N704G	Neutral	0.223
BRCA1	P38398-1.2	N704H	Neutral	0.1
BRCA1	P38398-1.2	N704I	Neutral	0.346
BRCA1	P38398-1.2	N704K	Neutral	0.191
BRCA1	P38398-1.2	N704L	Neutral	0.347
BRCA1	P38398-1.2	N704M	Neutral	0.271
BRCA1	P38398-1.2	N704P	Neutral	0.187
BRCA1	P38398-1.2	N704Q	Neutral	0.129
BRCA1	P38398-1.2	N704R	Neutral	0.239
BRCA1	P38398-1.2	N704S	Neutral	0.103
BRCA1	P38398-1.2	N704T	Neutral	0.095
BRCA1	P38398-1.2	N704V	Neutral	0.26
BRCA1	P38398-1.2	N704W	Pathogenic	0.642
BRCA1	P38398-1.2	N704Y	Neutral	0.353
BRCA1	P38398-1.2	A705C	Neutral	0.001
BRCA1	P38398-1.2	A705D	Neutral	0.003
BRCA1	P38398-1.2	A705E	Neutral	0.004
BRCA1	P38398-1.2	A705F	Neutral	0.009
BRCA1	P38398-1.2	A705G	Neutral	0.002
BRCA1	P38398-1.2	A705H	Neutral	0.006
BRCA1	P38398-1.2	A705I	Neutral	0.005
BRCA1	P38398-1.2	A705K	Neutral	0.006
BRCA1	P38398-1.2	A705L	Neutral	0.005
BRCA1	P38398-1.2	A705M	Neutral	0.005
BRCA1	P38398-1.2	A705N	Neutral	0.004
BRCA1	P38398-1.2	A705P	Neutral	0.002
BRCA1	P38398-1.2	A705Q	Neutral	0.004
BRCA1	P38398-1.2	A705R	Neutral	0.008
BRCA1	P38398-1.2	A705S	Neutral	0.001
BRCA1	P38398-1.2	A705T	Neutral	0.002
BRCA1	P38398-1.2	A705V	Neutral	0.002
BRCA1	P38398-1.2	A705W	Neutral	0.023
BRCA1	P38398-1.2	A705Y	Neutral	0.01
BRCA1	P38398-1.2	P706A	Pathogenic	0.551
BRCA1	P38398-1.2	P706C	Pathogenic	0.626
BRCA1	P38398-1.2	P706D	Neutral	0.424
BRCA1	P38398-1.2	P706E	Pathogenic	0.524
BRCA1	P38398-1.2	P706F	Pathogenic	0.855
BRCA1	P38398-1.2	P706G	Pathogenic	0.728
BRCA1	P38398-1.2	P706H	Pathogenic	0.663
BRCA1	P38398-1.2	P706I	Pathogenic	0.762
BRCA1	P38398-1.2	P706K	Pathogenic	0.661
BRCA1	P38398-1.2	P706L	Pathogenic	0.762
BRCA1	P38398-1.2	P706M	Pathogenic	0.692
BRCA1	P38398-1.2	P706N	Pathogenic	0.543
BRCA1	P38398-1.2	P706Q	Pathogenic	0.554
BRCA1	P38398-1.2	P706R	Pathogenic	0.789
BRCA1	P38398-1.2	P706S	Pathogenic	0.516
BRCA1	P38398-1.2	P706T	Neutral	0.44
BRCA1	P38398-1.2	P706V	Pathogenic	0.596
BRCA1	P38398-1.2	P706W	Pathogenic	0.916
BRCA1	P38398-1.2	P706Y	Pathogenic	0.826
BRCA1	P38398-1.2	G707A	Neutral	0.033
BRCA1	P38398-1.2	G707C	Neutral	0.134
BRCA1	P38398-1.2	G707D	Neutral	0.077
BRCA1	P38398-1.2	G707E	Neutral	0.152
BRCA1	P38398-1.2	G707F	Neutral	0.311
BRCA1	P38398-1.2	G707H	Neutral	0.182
BRCA1	P38398-1.2	G707I	Neutral	0.337
BRCA1	P38398-1.2	G707K	Neutral	0.241
BRCA1	P38398-1.2	G707L	Neutral	0.337
BRCA1	P38398-1.2	G707M	Neutral	0.263
BRCA1	P38398-1.2	G707N	Neutral	0.061
BRCA1	P38398-1.2	G707P	Neutral	0.105
BRCA1	P38398-1.2	G707Q	Neutral	0.168
BRCA1	P38398-1.2	G707R	Neutral	0.298
BRCA1	P38398-1.2	G707S	Neutral	0.038
BRCA1	P38398-1.2	G707T	Neutral	0.113
BRCA1	P38398-1.2	G707V	Neutral	0.19
BRCA1	P38398-1.2	G707W	Neutral	0.367
BRCA1	P38398-1.2	G707Y	Neutral	0.344
BRCA1	P38398-1.2	S708A	Neutral	0.0
BRCA1	P38398-1.2	S708C	Neutral	0.001
BRCA1	P38398-1.2	S708D	Neutral	0.001
BRCA1	P38398-1.2	S708E	Neutral	0.001
BRCA1	P38398-1.2	S708F	Neutral	0.004
BRCA1	P38398-1.2	S708G	Neutral	0.001
BRCA1	P38398-1.2	S708H	Neutral	0.002
BRCA1	P38398-1.2	S708I	Neutral	0.003
BRCA1	P38398-1.2	S708K	Neutral	0.002
BRCA1	P38398-1.2	S708L	Neutral	0.003
BRCA1	P38398-1.2	S708M	Neutral	0.002
BRCA1	P38398-1.2	S708N	Neutral	0.001
BRCA1	P38398-1.2	S708P	Neutral	0.001
BRCA1	P38398-1.2	S708Q	Neutral	0.001
BRCA1	P38398-1.2	S708R	Neutral	0.004
BRCA1	P38398-1.2	S708T	Neutral	0.001
BRCA1	P38398-1.2	S708V	Neutral	0.002
BRCA1	P38398-1.2	S708W	Neutral	0.011
BRCA1	P38398-1.2	S708Y	Neutral	0.005
BRCA1	P38398-1.2	F709A	Neutral	0.094
BRCA1	P38398-1.2	F709C	Neutral	0.064
BRCA1	P38398-1.2	F709D	Neutral	0.079
BRCA1	P38398-1.2	F709E	Neutral	0.054
BRCA1	P38398-1.2	F709G	Neutral	0.184
BRCA1	P38398-1.2	F709H	Neutral	0.023
BRCA1	P38398-1.2	F709I	Neutral	0.014
BRCA1	P38398-1.2	F709K	Neutral	0.031
BRCA1	P38398-1.2	F709L	Neutral	0.014
BRCA1	P38398-1.2	F709M	Neutral	0.014
BRCA1	P38398-1.2	F709N	Neutral	0.071
BRCA1	P38398-1.2	F709P	Neutral	0.115
BRCA1	P38398-1.2	F709Q	Neutral	0.049
BRCA1	P38398-1.2	F709R	Neutral	0.041
BRCA1	P38398-1.2	F709S	Neutral	0.082
BRCA1	P38398-1.2	F709T	Neutral	0.055
BRCA1	P38398-1.2	F709V	Neutral	0.03
BRCA1	P38398-1.2	F709W	Neutral	0.014
BRCA1	P38398-1.2	F709Y	Neutral	0.004
BRCA1	P38398-1.2	T710A	Neutral	0.3
BRCA1	P38398-1.2	T710C	Neutral	0.285
BRCA1	P38398-1.2	T710D	Neutral	0.262
BRCA1	P38398-1.2	T710E	Neutral	0.327
BRCA1	P38398-1.2	T710F	Pathogenic	0.552
BRCA1	P38398-1.2	T710G	Pathogenic	0.574
BRCA1	P38398-1.2	T710H	Neutral	0.465
BRCA1	P38398-1.2	T710I	Neutral	0.401
BRCA1	P38398-1.2	T710K	Neutral	0.463
BRCA1	P38398-1.2	T710L	Neutral	0.402
BRCA1	P38398-1.2	T710M	Neutral	0.404
BRCA1	P38398-1.2	T710N	Neutral	0.202
BRCA1	P38398-1.2	T710P	Neutral	0.269
BRCA1	P38398-1.2	T710Q	Neutral	0.354
BRCA1	P38398-1.2	T710R	Pathogenic	0.535
BRCA1	P38398-1.2	T710S	Neutral	0.206
BRCA1	P38398-1.2	T710V	Neutral	0.236
BRCA1	P38398-1.2	T710W	Pathogenic	0.695
BRCA1	P38398-1.2	T710Y	Pathogenic	0.588
BRCA1	P38398-1.2	K711A	Neutral	0.092
BRCA1	P38398-1.2	K711C	Neutral	0.12
BRCA1	P38398-1.2	K711D	Neutral	0.057
BRCA1	P38398-1.2	K711E	Neutral	0.019
BRCA1	P38398-1.2	K711F	Neutral	0.043
BRCA1	P38398-1.2	K711G	Neutral	0.183
BRCA1	P38398-1.2	K711H	Neutral	0.032
BRCA1	P38398-1.2	K711I	Neutral	0.054
BRCA1	P38398-1.2	K711L	Neutral	0.038
BRCA1	P38398-1.2	K711M	Neutral	0.027
BRCA1	P38398-1.2	K711N	Neutral	0.036
BRCA1	P38398-1.2	K711P	Neutral	0.057
BRCA1	P38398-1.2	K711Q	Neutral	0.017
BRCA1	P38398-1.2	K711R	Neutral	0.01
BRCA1	P38398-1.2	K711S	Neutral	0.058
BRCA1	P38398-1.2	K711T	Neutral	0.054
BRCA1	P38398-1.2	K711V	Neutral	0.058
BRCA1	P38398-1.2	K711W	Neutral	0.077
BRCA1	P38398-1.2	K711Y	Neutral	0.035
BRCA1	P38398-1.2	C712A	Neutral	0.04
BRCA1	P38398-1.2	C712D	Neutral	0.082
BRCA1	P38398-1.2	C712E	Neutral	0.161
BRCA1	P38398-1.2	C712F	Neutral	0.144
BRCA1	P38398-1.2	C712G	Neutral	0.159
BRCA1	P38398-1.2	C712H	Neutral	0.142
BRCA1	P38398-1.2	C712I	Neutral	0.084
BRCA1	P38398-1.2	C712K	Neutral	0.191
BRCA1	P38398-1.2	C712L	Neutral	0.084
BRCA1	P38398-1.2	C712M	Neutral	0.085
BRCA1	P38398-1.2	C712N	Neutral	0.091
BRCA1	P38398-1.2	C712P	Neutral	0.082
BRCA1	P38398-1.2	C712Q	Neutral	0.131
BRCA1	P38398-1.2	C712R	Neutral	0.24
BRCA1	P38398-1.2	C712S	Neutral	0.05
BRCA1	P38398-1.2	C712T	Neutral	0.044
BRCA1	P38398-1.2	C712V	Neutral	0.057
BRCA1	P38398-1.2	C712W	Neutral	0.237
BRCA1	P38398-1.2	C712Y	Neutral	0.163
BRCA1	P38398-1.2	S713A	Neutral	0.258
BRCA1	P38398-1.2	S713C	Neutral	0.454
BRCA1	P38398-1.2	S713D	Neutral	0.393
BRCA1	P38398-1.2	S713E	Neutral	0.492
BRCA1	P38398-1.2	S713F	Pathogenic	0.777
BRCA1	P38398-1.2	S713G	Neutral	0.434
BRCA1	P38398-1.2	S713H	Pathogenic	0.632
BRCA1	P38398-1.2	S713I	Pathogenic	0.732
BRCA1	P38398-1.2	S713K	Pathogenic	0.632
BRCA1	P38398-1.2	S713L	Pathogenic	0.733
BRCA1	P38398-1.2	S713M	Pathogenic	0.658
BRCA1	P38398-1.2	S713N	Neutral	0.336
BRCA1	P38398-1.2	S713P	Neutral	0.477
BRCA1	P38398-1.2	S713Q	Pathogenic	0.522
BRCA1	P38398-1.2	S713R	Pathogenic	0.767
BRCA1	P38398-1.2	S713T	Neutral	0.322
BRCA1	P38398-1.2	S713V	Pathogenic	0.645
BRCA1	P38398-1.2	S713W	Pathogenic	0.903
BRCA1	P38398-1.2	S713Y	Pathogenic	0.802
BRCA1	P38398-1.2	N714A	Neutral	0.054
BRCA1	P38398-1.2	N714C	Neutral	0.05
BRCA1	P38398-1.2	N714D	Neutral	0.011
BRCA1	P38398-1.2	N714E	Neutral	0.019
BRCA1	P38398-1.2	N714F	Neutral	0.09
BRCA1	P38398-1.2	N714G	Neutral	0.04
BRCA1	P38398-1.2	N714H	Neutral	0.016
BRCA1	P38398-1.2	N714I	Neutral	0.072
BRCA1	P38398-1.2	N714K	Neutral	0.033
BRCA1	P38398-1.2	N714L	Neutral	0.072
BRCA1	P38398-1.2	N714M	Neutral	0.052
BRCA1	P38398-1.2	N714P	Neutral	0.033
BRCA1	P38398-1.2	N714Q	Neutral	0.021
BRCA1	P38398-1.2	N714R	Neutral	0.044
BRCA1	P38398-1.2	N714S	Neutral	0.017
BRCA1	P38398-1.2	N714T	Neutral	0.015
BRCA1	P38398-1.2	N714V	Neutral	0.049
BRCA1	P38398-1.2	N714W	Neutral	0.209
BRCA1	P38398-1.2	N714Y	Neutral	0.074
BRCA1	P38398-1.2	T715A	Neutral	0.087
BRCA1	P38398-1.2	T715C	Neutral	0.081
BRCA1	P38398-1.2	T715D	Neutral	0.073
BRCA1	P38398-1.2	T715E	Neutral	0.097
BRCA1	P38398-1.2	T715F	Neutral	0.215
BRCA1	P38398-1.2	T715G	Neutral	0.231
BRCA1	P38398-1.2	T715H	Neutral	0.162
BRCA1	P38398-1.2	T715I	Neutral	0.13
BRCA1	P38398-1.2	T715K	Neutral	0.16
BRCA1	P38398-1.2	T715L	Neutral	0.13
BRCA1	P38398-1.2	T715M	Neutral	0.131
BRCA1	P38398-1.2	T715N	Neutral	0.053
BRCA1	P38398-1.2	T715P	Neutral	0.075
BRCA1	P38398-1.2	T715Q	Neutral	0.108
BRCA1	P38398-1.2	T715R	Neutral	0.203
BRCA1	P38398-1.2	T715S	Neutral	0.055
BRCA1	P38398-1.2	T715V	Neutral	0.064
BRCA1	P38398-1.2	T715W	Neutral	0.335
BRCA1	P38398-1.2	T715Y	Neutral	0.241
BRCA1	P38398-1.2	S716A	Neutral	0.0
BRCA1	P38398-1.2	S716C	Neutral	0.001
BRCA1	P38398-1.2	S716D	Neutral	0.001
BRCA1	P38398-1.2	S716E	Neutral	0.001
BRCA1	P38398-1.2	S716F	Neutral	0.005
BRCA1	P38398-1.2	S716G	Neutral	0.001
BRCA1	P38398-1.2	S716H	Neutral	0.002
BRCA1	P38398-1.2	S716I	Neutral	0.004
BRCA1	P38398-1.2	S716K	Neutral	0.002
BRCA1	P38398-1.2	S716L	Neutral	0.004
BRCA1	P38398-1.2	S716M	Neutral	0.003
BRCA1	P38398-1.2	S716N	Neutral	0.001
BRCA1	P38398-1.2	S716P	Neutral	0.001
BRCA1	P38398-1.2	S716Q	Neutral	0.001
BRCA1	P38398-1.2	S716R	Neutral	0.004
BRCA1	P38398-1.2	S716T	Neutral	0.001
BRCA1	P38398-1.2	S716V	Neutral	0.002
BRCA1	P38398-1.2	S716W	Neutral	0.012
BRCA1	P38398-1.2	S716Y	Neutral	0.005
BRCA1	P38398-1.2	E717A	Neutral	0.039
BRCA1	P38398-1.2	E717C	Neutral	0.072
BRCA1	P38398-1.2	E717D	Neutral	0.008
BRCA1	P38398-1.2	E717F	Neutral	0.054
BRCA1	P38398-1.2	E717G	Neutral	0.081
BRCA1	P38398-1.2	E717H	Neutral	0.013
BRCA1	P38398-1.2	E717I	Neutral	0.042
BRCA1	P38398-1.2	E717K	Neutral	0.014
BRCA1	P38398-1.2	E717L	Neutral	0.043
BRCA1	P38398-1.2	E717M	Neutral	0.03
BRCA1	P38398-1.2	E717N	Neutral	0.015
BRCA1	P38398-1.2	E717P	Neutral	0.023
BRCA1	P38398-1.2	E717Q	Neutral	0.006
BRCA1	P38398-1.2	E717R	Neutral	0.026
BRCA1	P38398-1.2	E717S	Neutral	0.024
BRCA1	P38398-1.2	E717T	Neutral	0.022
BRCA1	P38398-1.2	E717V	Neutral	0.024
BRCA1	P38398-1.2	E717W	Neutral	0.095
BRCA1	P38398-1.2	E717Y	Neutral	0.044
BRCA1	P38398-1.2	L718A	Neutral	0.075
BRCA1	P38398-1.2	L718C	Neutral	0.051
BRCA1	P38398-1.2	L718D	Neutral	0.123
BRCA1	P38398-1.2	L718E	Neutral	0.061
BRCA1	P38398-1.2	L718F	Neutral	0.021
BRCA1	P38398-1.2	L718G	Neutral	0.269
BRCA1	P38398-1.2	L718H	Neutral	0.051
BRCA1	P38398-1.2	L718I	Neutral	0.008
BRCA1	P38398-1.2	L718K	Neutral	0.04
BRCA1	P38398-1.2	L718M	Neutral	0.008
BRCA1	P38398-1.2	L718N	Neutral	0.08
BRCA1	P38398-1.2	L718P	Neutral	0.093
BRCA1	P38398-1.2	L718Q	Neutral	0.039
BRCA1	P38398-1.2	L718R	Neutral	0.052
BRCA1	P38398-1.2	L718S	Neutral	0.093
BRCA1	P38398-1.2	L718T	Neutral	0.044
BRCA1	P38398-1.2	L718V	Neutral	0.017
BRCA1	P38398-1.2	L718W	Neutral	0.074
BRCA1	P38398-1.2	L718Y	Neutral	0.033
BRCA1	P38398-1.2	K719A	Neutral	0.029
BRCA1	P38398-1.2	K719C	Neutral	0.039
BRCA1	P38398-1.2	K719D	Neutral	0.018
BRCA1	P38398-1.2	K719E	Neutral	0.006
BRCA1	P38398-1.2	K719F	Neutral	0.013
BRCA1	P38398-1.2	K719G	Neutral	0.063
BRCA1	P38398-1.2	K719H	Neutral	0.01
BRCA1	P38398-1.2	K719I	Neutral	0.017
BRCA1	P38398-1.2	K719L	Neutral	0.012
BRCA1	P38398-1.2	K719M	Neutral	0.008
BRCA1	P38398-1.2	K719N	Neutral	0.011
BRCA1	P38398-1.2	K719P	Neutral	0.018
BRCA1	P38398-1.2	K719Q	Neutral	0.005
BRCA1	P38398-1.2	K719R	Neutral	0.003
BRCA1	P38398-1.2	K719S	Neutral	0.018
BRCA1	P38398-1.2	K719T	Neutral	0.017
BRCA1	P38398-1.2	K719V	Neutral	0.018
BRCA1	P38398-1.2	K719W	Neutral	0.024
BRCA1	P38398-1.2	K719Y	Neutral	0.011
BRCA1	P38398-1.2	E720A	Pathogenic	0.752
BRCA1	P38398-1.2	E720C	Pathogenic	0.854
BRCA1	P38398-1.2	E720D	Neutral	0.378
BRCA1	P38398-1.2	E720F	Pathogenic	0.811
BRCA1	P38398-1.2	E720G	Pathogenic	0.87
BRCA1	P38398-1.2	E720H	Pathogenic	0.505
BRCA1	P38398-1.2	E720I	Pathogenic	0.771
BRCA1	P38398-1.2	E720K	Pathogenic	0.51
BRCA1	P38398-1.2	E720L	Pathogenic	0.771
BRCA1	P38398-1.2	E720M	Pathogenic	0.702
BRCA1	P38398-1.2	E720N	Pathogenic	0.53
BRCA1	P38398-1.2	E720P	Pathogenic	0.644
BRCA1	P38398-1.2	E720Q	Neutral	0.312
BRCA1	P38398-1.2	E720R	Pathogenic	0.667
BRCA1	P38398-1.2	E720S	Pathogenic	0.651
BRCA1	P38398-1.2	E720T	Pathogenic	0.631
BRCA1	P38398-1.2	E720V	Pathogenic	0.649
BRCA1	P38398-1.2	E720W	Pathogenic	0.888
BRCA1	P38398-1.2	E720Y	Pathogenic	0.776
BRCA1	P38398-1.2	F721A	Pathogenic	0.64
BRCA1	P38398-1.2	F721C	Pathogenic	0.541
BRCA1	P38398-1.2	F721D	Pathogenic	0.595
BRCA1	P38398-1.2	F721E	Neutral	0.497
BRCA1	P38398-1.2	F721G	Pathogenic	0.795
BRCA1	P38398-1.2	F721H	Neutral	0.284
BRCA1	P38398-1.2	F721I	Neutral	0.199
BRCA1	P38398-1.2	F721K	Neutral	0.355
BRCA1	P38398-1.2	F721L	Neutral	0.199
BRCA1	P38398-1.2	F721M	Neutral	0.198
BRCA1	P38398-1.2	F721N	Pathogenic	0.569
BRCA1	P38398-1.2	F721P	Pathogenic	0.69
BRCA1	P38398-1.2	F721Q	Neutral	0.471
BRCA1	P38398-1.2	F721R	Neutral	0.424
BRCA1	P38398-1.2	F721S	Pathogenic	0.607
BRCA1	P38398-1.2	F721T	Neutral	0.499
BRCA1	P38398-1.2	F721V	Neutral	0.351
BRCA1	P38398-1.2	F721W	Neutral	0.2
BRCA1	P38398-1.2	F721Y	Neutral	0.069
BRCA1	P38398-1.2	V722A	Pathogenic	0.827
BRCA1	P38398-1.2	V722C	Pathogenic	0.82
BRCA1	P38398-1.2	V722D	Pathogenic	0.891
BRCA1	P38398-1.2	V722E	Pathogenic	0.82
BRCA1	P38398-1.2	V722F	Pathogenic	0.853
BRCA1	P38398-1.2	V722G	Pathogenic	0.956
BRCA1	P38398-1.2	V722H	Pathogenic	0.89
BRCA1	P38398-1.2	V722I	Pathogenic	0.513
BRCA1	P38398-1.2	V722K	Pathogenic	0.89
BRCA1	P38398-1.2	V722L	Pathogenic	0.687
BRCA1	P38398-1.2	V722M	Pathogenic	0.688
BRCA1	P38398-1.2	V722N	Pathogenic	0.88
BRCA1	P38398-1.2	V722P	Pathogenic	0.857
BRCA1	P38398-1.2	V722Q	Pathogenic	0.837
BRCA1	P38398-1.2	V722R	Pathogenic	0.939
BRCA1	P38398-1.2	V722S	Pathogenic	0.896
BRCA1	P38398-1.2	V722T	Pathogenic	0.728
BRCA1	P38398-1.2	V722W	Pathogenic	0.957
BRCA1	P38398-1.2	V722Y	Pathogenic	0.869
BRCA1	P38398-1.2	N723A	Neutral	0.08
BRCA1	P38398-1.2	N723C	Neutral	0.075
BRCA1	P38398-1.2	N723D	Neutral	0.017
BRCA1	P38398-1.2	N723E	Neutral	0.029
BRCA1	P38398-1.2	N723F	Neutral	0.131
BRCA1	P38398-1.2	N723G	Neutral	0.06
BRCA1	P38398-1.2	N723H	Neutral	0.024
BRCA1	P38398-1.2	N723I	Neutral	0.106
BRCA1	P38398-1.2	N723K	Neutral	0.05
BRCA1	P38398-1.2	N723L	Neutral	0.106
BRCA1	P38398-1.2	N723M	Neutral	0.077
BRCA1	P38398-1.2	N723P	Neutral	0.049
BRCA1	P38398-1.2	N723Q	Neutral	0.032
BRCA1	P38398-1.2	N723R	Neutral	0.066
BRCA1	P38398-1.2	N723S	Neutral	0.025
BRCA1	P38398-1.2	N723T	Neutral	0.023
BRCA1	P38398-1.2	N723V	Neutral	0.073
BRCA1	P38398-1.2	N723W	Neutral	0.287
BRCA1	P38398-1.2	N723Y	Neutral	0.109
BRCA1	P38398-1.2	P724A	Pathogenic	0.632
BRCA1	P38398-1.2	P724C	Pathogenic	0.701
BRCA1	P38398-1.2	P724D	Pathogenic	0.508
BRCA1	P38398-1.2	P724E	Pathogenic	0.607
BRCA1	P38398-1.2	P724F	Pathogenic	0.892
BRCA1	P38398-1.2	P724G	Pathogenic	0.79
BRCA1	P38398-1.2	P724H	Pathogenic	0.734
BRCA1	P38398-1.2	P724I	Pathogenic	0.818
BRCA1	P38398-1.2	P724K	Pathogenic	0.732
BRCA1	P38398-1.2	P724L	Pathogenic	0.818
BRCA1	P38398-1.2	P724M	Pathogenic	0.759
BRCA1	P38398-1.2	P724N	Pathogenic	0.625
BRCA1	P38398-1.2	P724Q	Pathogenic	0.635
BRCA1	P38398-1.2	P724R	Pathogenic	0.84
BRCA1	P38398-1.2	P724S	Pathogenic	0.599
BRCA1	P38398-1.2	P724T	Pathogenic	0.524
BRCA1	P38398-1.2	P724V	Pathogenic	0.674
BRCA1	P38398-1.2	P724W	Pathogenic	0.938
BRCA1	P38398-1.2	P724Y	Pathogenic	0.869
BRCA1	P38398-1.2	S725A	Neutral	0.06
BRCA1	P38398-1.2	S725C	Neutral	0.132
BRCA1	P38398-1.2	S725D	Neutral	0.107
BRCA1	P38398-1.2	S725E	Neutral	0.151
BRCA1	P38398-1.2	S725F	Neutral	0.391
BRCA1	P38398-1.2	S725G	Neutral	0.124
BRCA1	P38398-1.2	S725H	Neutral	0.24
BRCA1	P38398-1.2	S725I	Neutral	0.335
BRCA1	P38398-1.2	S725K	Neutral	0.24
BRCA1	P38398-1.2	S725L	Neutral	0.335
BRCA1	P38398-1.2	S725M	Neutral	0.261
BRCA1	P38398-1.2	S725N	Neutral	0.085
BRCA1	P38398-1.2	S725P	Neutral	0.144
BRCA1	P38398-1.2	S725Q	Neutral	0.167
BRCA1	P38398-1.2	S725R	Neutral	0.377
BRCA1	P38398-1.2	S725T	Neutral	0.08
BRCA1	P38398-1.2	S725V	Neutral	0.25
BRCA1	P38398-1.2	S725W	Pathogenic	0.631
BRCA1	P38398-1.2	S725Y	Neutral	0.427
BRCA1	P38398-1.2	L726A	Neutral	0.457
BRCA1	P38398-1.2	L726C	Neutral	0.358
BRCA1	P38398-1.2	L726D	Pathogenic	0.59
BRCA1	P38398-1.2	L726E	Neutral	0.402
BRCA1	P38398-1.2	L726F	Neutral	0.177
BRCA1	P38398-1.2	L726G	Pathogenic	0.792
BRCA1	P38398-1.2	L726H	Neutral	0.358
BRCA1	P38398-1.2	L726I	Neutral	0.075
BRCA1	P38398-1.2	L726K	Neutral	0.298
BRCA1	P38398-1.2	L726M	Neutral	0.075
BRCA1	P38398-1.2	L726N	Neutral	0.473
BRCA1	P38398-1.2	L726P	Pathogenic	0.513
BRCA1	P38398-1.2	L726Q	Neutral	0.296
BRCA1	P38398-1.2	L726R	Neutral	0.362
BRCA1	P38398-1.2	L726S	Pathogenic	0.512
BRCA1	P38398-1.2	L726T	Neutral	0.32
BRCA1	P38398-1.2	L726V	Neutral	0.151
BRCA1	P38398-1.2	L726W	Neutral	0.452
BRCA1	P38398-1.2	L726Y	Neutral	0.259
BRCA1	P38398-1.2	P727A	Neutral	0.023
BRCA1	P38398-1.2	P727C	Neutral	0.032
BRCA1	P38398-1.2	P727D	Neutral	0.014
BRCA1	P38398-1.2	P727E	Neutral	0.021
BRCA1	P38398-1.2	P727F	Neutral	0.103
BRCA1	P38398-1.2	P727G	Neutral	0.05
BRCA1	P38398-1.2	P727H	Neutral	0.037
BRCA1	P38398-1.2	P727I	Neutral	0.059
BRCA1	P38398-1.2	P727K	Neutral	0.037
BRCA1	P38398-1.2	P727L	Neutral	0.059
BRCA1	P38398-1.2	P727M	Neutral	0.042
BRCA1	P38398-1.2	P727N	Neutral	0.023
BRCA1	P38398-1.2	P727Q	Neutral	0.024
BRCA1	P38398-1.2	P727R	Neutral	0.068
BRCA1	P38398-1.2	P727S	Neutral	0.02
BRCA1	P38398-1.2	P727T	Neutral	0.015
BRCA1	P38398-1.2	P727V	Neutral	0.028
BRCA1	P38398-1.2	P727W	Neutral	0.175
BRCA1	P38398-1.2	P727Y	Neutral	0.085
BRCA1	P38398-1.2	R728A	Pathogenic	0.629
BRCA1	P38398-1.2	R728C	Pathogenic	0.694
BRCA1	P38398-1.2	R728D	Pathogenic	0.594
BRCA1	P38398-1.2	R728E	Neutral	0.321
BRCA1	P38398-1.2	R728F	Neutral	0.43
BRCA1	P38398-1.2	R728G	Pathogenic	0.789
BRCA1	P38398-1.2	R728H	Neutral	0.276
BRCA1	P38398-1.2	R728I	Neutral	0.49
BRCA1	P38398-1.2	R728K	Neutral	0.114
BRCA1	P38398-1.2	R728L	Neutral	0.401
BRCA1	P38398-1.2	R728M	Neutral	0.319
BRCA1	P38398-1.2	R728N	Neutral	0.386
BRCA1	P38398-1.2	R728P	Pathogenic	0.592
BRCA1	P38398-1.2	R728Q	Neutral	0.225
BRCA1	P38398-1.2	R728S	Pathogenic	0.599
BRCA1	P38398-1.2	R728T	Neutral	0.488
BRCA1	P38398-1.2	R728V	Pathogenic	0.597
BRCA1	P38398-1.2	R728W	Neutral	0.438
BRCA1	P38398-1.2	R728Y	Neutral	0.318
BRCA1	P38398-1.2	E729A	Neutral	0.48
BRCA1	P38398-1.2	E729C	Pathogenic	0.64
BRCA1	P38398-1.2	E729D	Neutral	0.156
BRCA1	P38398-1.2	E729F	Pathogenic	0.565
BRCA1	P38398-1.2	E729G	Pathogenic	0.671
BRCA1	P38398-1.2	E729H	Neutral	0.236
BRCA1	P38398-1.2	E729I	Pathogenic	0.505
BRCA1	P38398-1.2	E729K	Neutral	0.24
BRCA1	P38398-1.2	E729L	Pathogenic	0.505
BRCA1	P38398-1.2	E729M	Neutral	0.417
BRCA1	P38398-1.2	E729N	Neutral	0.255
BRCA1	P38398-1.2	E729P	Neutral	0.354
BRCA1	P38398-1.2	E729Q	Neutral	0.121
BRCA1	P38398-1.2	E729R	Neutral	0.377
BRCA1	P38398-1.2	E729S	Neutral	0.361
BRCA1	P38398-1.2	E729T	Neutral	0.341
BRCA1	P38398-1.2	E729V	Neutral	0.359
BRCA1	P38398-1.2	E729W	Pathogenic	0.706
BRCA1	P38398-1.2	E729Y	Pathogenic	0.512
BRCA1	P38398-1.2	E730A	Neutral	0.292
BRCA1	P38398-1.2	E730C	Neutral	0.443
BRCA1	P38398-1.2	E730D	Neutral	0.076
BRCA1	P38398-1.2	E730F	Neutral	0.367
BRCA1	P38398-1.2	E730G	Neutral	0.476
BRCA1	P38398-1.2	E730H	Neutral	0.121
BRCA1	P38398-1.2	E730I	Neutral	0.313
BRCA1	P38398-1.2	E730K	Neutral	0.123
BRCA1	P38398-1.2	E730L	Neutral	0.313
BRCA1	P38398-1.2	E730M	Neutral	0.242
BRCA1	P38398-1.2	E730N	Neutral	0.133
BRCA1	P38398-1.2	E730P	Neutral	0.197
BRCA1	P38398-1.2	E730Q	Neutral	0.058
BRCA1	P38398-1.2	E730R	Neutral	0.213
BRCA1	P38398-1.2	E730S	Neutral	0.201
BRCA1	P38398-1.2	E730T	Neutral	0.188
BRCA1	P38398-1.2	E730V	Neutral	0.2
BRCA1	P38398-1.2	E730W	Pathogenic	0.517
BRCA1	P38398-1.2	E730Y	Neutral	0.319
BRCA1	P38398-1.2	K731A	Neutral	0.001
BRCA1	P38398-1.2	K731C	Neutral	0.001
BRCA1	P38398-1.2	K731D	Neutral	0.0
BRCA1	P38398-1.2	K731E	Neutral	0.0
BRCA1	P38398-1.2	K731F	Neutral	0.0
BRCA1	P38398-1.2	K731G	Neutral	0.001
BRCA1	P38398-1.2	K731H	Neutral	0.0
BRCA1	P38398-1.2	K731I	Neutral	0.0
BRCA1	P38398-1.2	K731L	Neutral	0.0
BRCA1	P38398-1.2	K731M	Neutral	0.0
BRCA1	P38398-1.2	K731N	Neutral	0.0
BRCA1	P38398-1.2	K731P	Neutral	0.0
BRCA1	P38398-1.2	K731Q	Neutral	0.0
BRCA1	P38398-1.2	K731R	Neutral	0.0
BRCA1	P38398-1.2	K731S	Neutral	0.0
BRCA1	P38398-1.2	K731T	Neutral	0.0
BRCA1	P38398-1.2	K731V	Neutral	0.0
BRCA1	P38398-1.2	K731W	Neutral	0.0
BRCA1	P38398-1.2	K731Y	Neutral	0.0
BRCA1	P38398-1.2	E732A	Neutral	0.416
BRCA1	P38398-1.2	E732C	Pathogenic	0.579
BRCA1	P38398-1.2	E732D	Neutral	0.125
BRCA1	P38398-1.2	E732F	Pathogenic	0.501
BRCA1	P38398-1.2	E732G	Pathogenic	0.611
BRCA1	P38398-1.2	E732H	Neutral	0.193
BRCA1	P38398-1.2	E732I	Neutral	0.44
BRCA1	P38398-1.2	E732K	Neutral	0.196
BRCA1	P38398-1.2	E732L	Neutral	0.441
BRCA1	P38398-1.2	E732M	Neutral	0.356
BRCA1	P38398-1.2	E732N	Neutral	0.209
BRCA1	P38398-1.2	E732P	Neutral	0.298
BRCA1	P38398-1.2	E732Q	Neutral	0.096
BRCA1	P38398-1.2	E732R	Neutral	0.319
BRCA1	P38398-1.2	E732S	Neutral	0.304
BRCA1	P38398-1.2	E732T	Neutral	0.286
BRCA1	P38398-1.2	E732V	Neutral	0.302
BRCA1	P38398-1.2	E732W	Pathogenic	0.65
BRCA1	P38398-1.2	E732Y	Neutral	0.448
BRCA1	P38398-1.2	E733A	Neutral	0.264
BRCA1	P38398-1.2	E733C	Neutral	0.41
BRCA1	P38398-1.2	E733D	Neutral	0.067
BRCA1	P38398-1.2	E733F	Neutral	0.337
BRCA1	P38398-1.2	E733G	Neutral	0.443
BRCA1	P38398-1.2	E733H	Neutral	0.108
BRCA1	P38398-1.2	E733I	Neutral	0.284
BRCA1	P38398-1.2	E733K	Neutral	0.11
BRCA1	P38398-1.2	E733L	Neutral	0.285
BRCA1	P38398-1.2	E733M	Neutral	0.218
BRCA1	P38398-1.2	E733N	Neutral	0.118
BRCA1	P38398-1.2	E733P	Neutral	0.176
BRCA1	P38398-1.2	E733Q	Neutral	0.051
BRCA1	P38398-1.2	E733R	Neutral	0.191
BRCA1	P38398-1.2	E733S	Neutral	0.18
BRCA1	P38398-1.2	E733T	Neutral	0.168
BRCA1	P38398-1.2	E733V	Neutral	0.179
BRCA1	P38398-1.2	E733W	Neutral	0.484
BRCA1	P38398-1.2	E733Y	Neutral	0.29
BRCA1	P38398-1.2	K734A	Neutral	0.021
BRCA1	P38398-1.2	K734C	Neutral	0.029
BRCA1	P38398-1.2	K734D	Neutral	0.013
BRCA1	P38398-1.2	K734E	Neutral	0.004
BRCA1	P38398-1.2	K734F	Neutral	0.01
BRCA1	P38398-1.2	K734G	Neutral	0.046
BRCA1	P38398-1.2	K734H	Neutral	0.007
BRCA1	P38398-1.2	K734I	Neutral	0.012
BRCA1	P38398-1.2	K734L	Neutral	0.009
BRCA1	P38398-1.2	K734M	Neutral	0.006
BRCA1	P38398-1.2	K734N	Neutral	0.008
BRCA1	P38398-1.2	K734P	Neutral	0.013
BRCA1	P38398-1.2	K734Q	Neutral	0.004
BRCA1	P38398-1.2	K734R	Neutral	0.002
BRCA1	P38398-1.2	K734S	Neutral	0.013
BRCA1	P38398-1.2	K734T	Neutral	0.012
BRCA1	P38398-1.2	K734V	Neutral	0.013
BRCA1	P38398-1.2	K734W	Neutral	0.018
BRCA1	P38398-1.2	K734Y	Neutral	0.008
BRCA1	P38398-1.2	L735A	Neutral	0.089
BRCA1	P38398-1.2	L735C	Neutral	0.061
BRCA1	P38398-1.2	L735D	Neutral	0.143
BRCA1	P38398-1.2	L735E	Neutral	0.072
BRCA1	P38398-1.2	L735F	Neutral	0.024
BRCA1	P38398-1.2	L735G	Neutral	0.305
BRCA1	P38398-1.2	L735H	Neutral	0.061
BRCA1	P38398-1.2	L735I	Neutral	0.009
BRCA1	P38398-1.2	L735K	Neutral	0.047
BRCA1	P38398-1.2	L735M	Neutral	0.009
BRCA1	P38398-1.2	L735N	Neutral	0.094
BRCA1	P38398-1.2	L735P	Neutral	0.109
BRCA1	P38398-1.2	L735Q	Neutral	0.047
BRCA1	P38398-1.2	L735R	Neutral	0.062
BRCA1	P38398-1.2	L735S	Neutral	0.109
BRCA1	P38398-1.2	L735T	Neutral	0.052
BRCA1	P38398-1.2	L735V	Neutral	0.02
BRCA1	P38398-1.2	L735W	Neutral	0.087
BRCA1	P38398-1.2	L735Y	Neutral	0.039
BRCA1	P38398-1.2	E736A	Neutral	0.079
BRCA1	P38398-1.2	E736C	Neutral	0.142
BRCA1	P38398-1.2	E736D	Neutral	0.017
BRCA1	P38398-1.2	E736F	Neutral	0.108
BRCA1	P38398-1.2	E736G	Neutral	0.159
BRCA1	P38398-1.2	E736H	Neutral	0.028
BRCA1	P38398-1.2	E736I	Neutral	0.086
BRCA1	P38398-1.2	E736K	Neutral	0.029
BRCA1	P38398-1.2	E736L	Neutral	0.087
BRCA1	P38398-1.2	E736M	Neutral	0.062
BRCA1	P38398-1.2	E736N	Neutral	0.031
BRCA1	P38398-1.2	E736P	Neutral	0.049
BRCA1	P38398-1.2	E736Q	Neutral	0.013
BRCA1	P38398-1.2	E736R	Neutral	0.053
BRCA1	P38398-1.2	E736S	Neutral	0.05
BRCA1	P38398-1.2	E736T	Neutral	0.046
BRCA1	P38398-1.2	E736V	Neutral	0.05
BRCA1	P38398-1.2	E736W	Neutral	0.182
BRCA1	P38398-1.2	E736Y	Neutral	0.089
BRCA1	P38398-1.2	T737A	Neutral	0.169
BRCA1	P38398-1.2	T737C	Neutral	0.159
BRCA1	P38398-1.2	T737D	Neutral	0.144
BRCA1	P38398-1.2	T737E	Neutral	0.187
BRCA1	P38398-1.2	T737F	Neutral	0.369
BRCA1	P38398-1.2	T737G	Neutral	0.39
BRCA1	P38398-1.2	T737H	Neutral	0.291
BRCA1	P38398-1.2	T737I	Neutral	0.241
BRCA1	P38398-1.2	T737K	Neutral	0.29
BRCA1	P38398-1.2	T737L	Neutral	0.241
BRCA1	P38398-1.2	T737M	Neutral	0.243
BRCA1	P38398-1.2	T737N	Neutral	0.107
BRCA1	P38398-1.2	T737P	Neutral	0.148
BRCA1	P38398-1.2	T737Q	Neutral	0.206
BRCA1	P38398-1.2	T737R	Neutral	0.352
BRCA1	P38398-1.2	T737S	Neutral	0.11
BRCA1	P38398-1.2	T737V	Neutral	0.128
BRCA1	P38398-1.2	T737W	Pathogenic	0.519
BRCA1	P38398-1.2	T737Y	Neutral	0.404
BRCA1	P38398-1.2	V738A	Neutral	0.018
BRCA1	P38398-1.2	V738C	Neutral	0.018
BRCA1	P38398-1.2	V738D	Neutral	0.031
BRCA1	P38398-1.2	V738E	Neutral	0.018
BRCA1	P38398-1.2	V738F	Neutral	0.022
BRCA1	P38398-1.2	V738G	Neutral	0.078
BRCA1	P38398-1.2	V738H	Neutral	0.031
BRCA1	P38398-1.2	V738I	Neutral	0.004
BRCA1	P38398-1.2	V738K	Neutral	0.031
BRCA1	P38398-1.2	V738L	Neutral	0.009
BRCA1	P38398-1.2	V738M	Neutral	0.009
BRCA1	P38398-1.2	V738N	Neutral	0.028
BRCA1	P38398-1.2	V738P	Neutral	0.023
BRCA1	P38398-1.2	V738Q	Neutral	0.02
BRCA1	P38398-1.2	V738R	Neutral	0.057
BRCA1	P38398-1.2	V738S	Neutral	0.033
BRCA1	P38398-1.2	V738T	Neutral	0.01
BRCA1	P38398-1.2	V738W	Neutral	0.08
BRCA1	P38398-1.2	V738Y	Neutral	0.025
BRCA1	P38398-1.2	K739A	Neutral	0.274
BRCA1	P38398-1.2	K739C	Neutral	0.336
BRCA1	P38398-1.2	K739D	Neutral	0.184
BRCA1	P38398-1.2	K739E	Neutral	0.068
BRCA1	P38398-1.2	K739F	Neutral	0.144
BRCA1	P38398-1.2	K739G	Neutral	0.454
BRCA1	P38398-1.2	K739H	Neutral	0.109
BRCA1	P38398-1.2	K739I	Neutral	0.176
BRCA1	P38398-1.2	K739L	Neutral	0.13
BRCA1	P38398-1.2	K739M	Neutral	0.095
BRCA1	P38398-1.2	K739N	Neutral	0.123
BRCA1	P38398-1.2	K739P	Neutral	0.183
BRCA1	P38398-1.2	K739Q	Neutral	0.061
BRCA1	P38398-1.2	K739R	Neutral	0.037
BRCA1	P38398-1.2	K739S	Neutral	0.188
BRCA1	P38398-1.2	K739T	Neutral	0.175
BRCA1	P38398-1.2	K739V	Neutral	0.187
BRCA1	P38398-1.2	K739W	Neutral	0.236
BRCA1	P38398-1.2	K739Y	Neutral	0.119
BRCA1	P38398-1.2	V740A	Neutral	0.055
BRCA1	P38398-1.2	V740C	Neutral	0.053
BRCA1	P38398-1.2	V740D	Neutral	0.091
BRCA1	P38398-1.2	V740E	Neutral	0.053
BRCA1	P38398-1.2	V740F	Neutral	0.066
BRCA1	P38398-1.2	V740G	Neutral	0.208
BRCA1	P38398-1.2	V740H	Neutral	0.09
BRCA1	P38398-1.2	V740I	Neutral	0.013
BRCA1	P38398-1.2	V740K	Neutral	0.09
BRCA1	P38398-1.2	V740L	Neutral	0.026
BRCA1	P38398-1.2	V740M	Neutral	0.026
BRCA1	P38398-1.2	V740N	Neutral	0.082
BRCA1	P38398-1.2	V740P	Neutral	0.068
BRCA1	P38398-1.2	V740Q	Neutral	0.059
BRCA1	P38398-1.2	V740R	Neutral	0.159
BRCA1	P38398-1.2	V740S	Neutral	0.095
BRCA1	P38398-1.2	V740T	Neutral	0.032
BRCA1	P38398-1.2	V740W	Neutral	0.213
BRCA1	P38398-1.2	V740Y	Neutral	0.075
BRCA1	P38398-1.2	S741A	Neutral	0.206
BRCA1	P38398-1.2	S741C	Neutral	0.383
BRCA1	P38398-1.2	S741D	Neutral	0.326
BRCA1	P38398-1.2	S741E	Neutral	0.42
BRCA1	P38398-1.2	S741F	Pathogenic	0.723
BRCA1	P38398-1.2	S741G	Neutral	0.365
BRCA1	P38398-1.2	S741H	Pathogenic	0.562
BRCA1	P38398-1.2	S741I	Pathogenic	0.672
BRCA1	P38398-1.2	S741K	Pathogenic	0.562
BRCA1	P38398-1.2	S741L	Pathogenic	0.672
BRCA1	P38398-1.2	S741M	Pathogenic	0.59
BRCA1	P38398-1.2	S741N	Neutral	0.274
BRCA1	P38398-1.2	S741P	Neutral	0.405
BRCA1	P38398-1.2	S741Q	Neutral	0.449
BRCA1	P38398-1.2	S741R	Pathogenic	0.711
BRCA1	P38398-1.2	S741T	Neutral	0.262
BRCA1	P38398-1.2	S741V	Pathogenic	0.576
BRCA1	P38398-1.2	S741W	Pathogenic	0.874
BRCA1	P38398-1.2	S741Y	Pathogenic	0.752
BRCA1	P38398-1.2	N742A	Neutral	0.074
BRCA1	P38398-1.2	N742C	Neutral	0.069
BRCA1	P38398-1.2	N742D	Neutral	0.016
BRCA1	P38398-1.2	N742E	Neutral	0.027
BRCA1	P38398-1.2	N742F	Neutral	0.123
BRCA1	P38398-1.2	N742G	Neutral	0.056
BRCA1	P38398-1.2	N742H	Neutral	0.023
BRCA1	P38398-1.2	N742I	Neutral	0.099
BRCA1	P38398-1.2	N742K	Neutral	0.046
BRCA1	P38398-1.2	N742L	Neutral	0.099
BRCA1	P38398-1.2	N742M	Neutral	0.071
BRCA1	P38398-1.2	N742P	Neutral	0.045
BRCA1	P38398-1.2	N742Q	Neutral	0.03
BRCA1	P38398-1.2	N742R	Neutral	0.061
BRCA1	P38398-1.2	N742S	Neutral	0.023
BRCA1	P38398-1.2	N742T	Neutral	0.021
BRCA1	P38398-1.2	N742V	Neutral	0.068
BRCA1	P38398-1.2	N742W	Neutral	0.271
BRCA1	P38398-1.2	N742Y	Neutral	0.101
BRCA1	P38398-1.2	N743A	Neutral	0.038
BRCA1	P38398-1.2	N743C	Neutral	0.036
BRCA1	P38398-1.2	N743D	Neutral	0.008
BRCA1	P38398-1.2	N743E	Neutral	0.014
BRCA1	P38398-1.2	N743F	Neutral	0.065
BRCA1	P38398-1.2	N743G	Neutral	0.029
BRCA1	P38398-1.2	N743H	Neutral	0.011
BRCA1	P38398-1.2	N743I	Neutral	0.052
BRCA1	P38398-1.2	N743K	Neutral	0.024
BRCA1	P38398-1.2	N743L	Neutral	0.052
BRCA1	P38398-1.2	N743M	Neutral	0.037
BRCA1	P38398-1.2	N743P	Neutral	0.023
BRCA1	P38398-1.2	N743Q	Neutral	0.015
BRCA1	P38398-1.2	N743R	Neutral	0.031
BRCA1	P38398-1.2	N743S	Neutral	0.012
BRCA1	P38398-1.2	N743T	Neutral	0.011
BRCA1	P38398-1.2	N743V	Neutral	0.035
BRCA1	P38398-1.2	N743W	Neutral	0.156
BRCA1	P38398-1.2	N743Y	Neutral	0.053
BRCA1	P38398-1.2	A744C	Neutral	0.051
BRCA1	P38398-1.2	A744D	Neutral	0.11
BRCA1	P38398-1.2	A744E	Neutral	0.114
BRCA1	P38398-1.2	A744F	Neutral	0.245
BRCA1	P38398-1.2	A744G	Neutral	0.051
BRCA1	P38398-1.2	A744H	Neutral	0.186
BRCA1	P38398-1.2	A744I	Neutral	0.15
BRCA1	P38398-1.2	A744K	Neutral	0.185
BRCA1	P38398-1.2	A744L	Neutral	0.15
BRCA1	P38398-1.2	A744M	Neutral	0.152
BRCA1	P38398-1.2	A744N	Neutral	0.121
BRCA1	P38398-1.2	A744P	Neutral	0.078
BRCA1	P38398-1.2	A744Q	Neutral	0.126
BRCA1	P38398-1.2	A744R	Neutral	0.232
BRCA1	P38398-1.2	A744S	Neutral	0.027
BRCA1	P38398-1.2	A744T	Neutral	0.06
BRCA1	P38398-1.2	A744V	Neutral	0.075
BRCA1	P38398-1.2	A744W	Neutral	0.463
BRCA1	P38398-1.2	A744Y	Neutral	0.274
BRCA1	P38398-1.2	E745A	Neutral	0.03
BRCA1	P38398-1.2	E745C	Neutral	0.056
BRCA1	P38398-1.2	E745D	Neutral	0.006
BRCA1	P38398-1.2	E745F	Neutral	0.042
BRCA1	P38398-1.2	E745G	Neutral	0.064
BRCA1	P38398-1.2	E745H	Neutral	0.01
BRCA1	P38398-1.2	E745I	Neutral	0.033
BRCA1	P38398-1.2	E745K	Neutral	0.01
BRCA1	P38398-1.2	E745L	Neutral	0.033
BRCA1	P38398-1.2	E745M	Neutral	0.023
BRCA1	P38398-1.2	E745N	Neutral	0.011
BRCA1	P38398-1.2	E745P	Neutral	0.018
BRCA1	P38398-1.2	E745Q	Neutral	0.005
BRCA1	P38398-1.2	E745R	Neutral	0.02
BRCA1	P38398-1.2	E745S	Neutral	0.018
BRCA1	P38398-1.2	E745T	Neutral	0.017
BRCA1	P38398-1.2	E745V	Neutral	0.018
BRCA1	P38398-1.2	E745W	Neutral	0.074
BRCA1	P38398-1.2	E745Y	Neutral	0.034
BRCA1	P38398-1.2	D746A	Pathogenic	0.678
BRCA1	P38398-1.2	D746C	Pathogenic	0.663
BRCA1	P38398-1.2	D746E	Neutral	0.305
BRCA1	P38398-1.2	D746F	Pathogenic	0.821
BRCA1	P38398-1.2	D746G	Pathogenic	0.692
BRCA1	P38398-1.2	D746H	Pathogenic	0.611
BRCA1	P38398-1.2	D746I	Pathogenic	0.783
BRCA1	P38398-1.2	D746K	Pathogenic	0.699
BRCA1	P38398-1.2	D746L	Pathogenic	0.838
BRCA1	P38398-1.2	D746M	Pathogenic	0.784
BRCA1	P38398-1.2	D746N	Neutral	0.321
BRCA1	P38398-1.2	D746P	Neutral	0.466
BRCA1	P38398-1.2	D746Q	Pathogenic	0.501
BRCA1	P38398-1.2	D746R	Pathogenic	0.817
BRCA1	P38398-1.2	D746S	Neutral	0.473
BRCA1	P38398-1.2	D746T	Neutral	0.473
BRCA1	P38398-1.2	D746V	Pathogenic	0.705
BRCA1	P38398-1.2	D746W	Pathogenic	0.924
BRCA1	P38398-1.2	D746Y	Pathogenic	0.842
BRCA1	P38398-1.2	P747A	Neutral	0.287
BRCA1	P38398-1.2	P747C	Neutral	0.354
BRCA1	P38398-1.2	P747D	Neutral	0.195
BRCA1	P38398-1.2	P747E	Neutral	0.266
BRCA1	P38398-1.2	P747F	Pathogenic	0.659
BRCA1	P38398-1.2	P747G	Neutral	0.467
BRCA1	P38398-1.2	P747H	Neutral	0.392
BRCA1	P38398-1.2	P747I	Pathogenic	0.512
BRCA1	P38398-1.2	P747K	Neutral	0.39
BRCA1	P38398-1.2	P747L	Pathogenic	0.513
BRCA1	P38398-1.2	P747M	Neutral	0.425
BRCA1	P38398-1.2	P747N	Neutral	0.281
BRCA1	P38398-1.2	P747Q	Neutral	0.289
BRCA1	P38398-1.2	P747R	Pathogenic	0.551
BRCA1	P38398-1.2	P747S	Neutral	0.259
BRCA1	P38398-1.2	P747T	Neutral	0.205
BRCA1	P38398-1.2	P747V	Neutral	0.326
BRCA1	P38398-1.2	P747W	Pathogenic	0.781
BRCA1	P38398-1.2	P747Y	Pathogenic	0.609
BRCA1	P38398-1.2	K748A	Neutral	0.496
BRCA1	P38398-1.2	K748C	Pathogenic	0.569
BRCA1	P38398-1.2	K748D	Neutral	0.371
BRCA1	P38398-1.2	K748E	Neutral	0.16
BRCA1	P38398-1.2	K748F	Neutral	0.304
BRCA1	P38398-1.2	K748G	Pathogenic	0.685
BRCA1	P38398-1.2	K748H	Neutral	0.241
BRCA1	P38398-1.2	K748I	Neutral	0.358
BRCA1	P38398-1.2	K748L	Neutral	0.28
BRCA1	P38398-1.2	K748M	Neutral	0.214
BRCA1	P38398-1.2	K748N	Neutral	0.268
BRCA1	P38398-1.2	K748P	Neutral	0.369
BRCA1	P38398-1.2	K748Q	Neutral	0.145
BRCA1	P38398-1.2	K748R	Neutral	0.091
BRCA1	P38398-1.2	K748S	Neutral	0.376
BRCA1	P38398-1.2	K748T	Neutral	0.356
BRCA1	P38398-1.2	K748V	Neutral	0.374
BRCA1	P38398-1.2	K748W	Neutral	0.447
BRCA1	P38398-1.2	K748Y	Neutral	0.261
BRCA1	P38398-1.2	D749A	Neutral	0.277
BRCA1	P38398-1.2	D749C	Neutral	0.263
BRCA1	P38398-1.2	D749E	Neutral	0.074
BRCA1	P38398-1.2	D749F	Neutral	0.455
BRCA1	P38398-1.2	D749G	Neutral	0.29
BRCA1	P38398-1.2	D749H	Neutral	0.222
BRCA1	P38398-1.2	D749I	Neutral	0.396
BRCA1	P38398-1.2	D749K	Neutral	0.297
BRCA1	P38398-1.2	D749L	Neutral	0.486
BRCA1	P38398-1.2	D749M	Neutral	0.398
BRCA1	P38398-1.2	D749N	Neutral	0.079
BRCA1	P38398-1.2	D749P	Neutral	0.137
BRCA1	P38398-1.2	D749Q	Neutral	0.155
BRCA1	P38398-1.2	D749R	Neutral	0.448
BRCA1	P38398-1.2	D749S	Neutral	0.14
BRCA1	P38398-1.2	D749T	Neutral	0.141
BRCA1	P38398-1.2	D749V	Neutral	0.303
BRCA1	P38398-1.2	D749W	Pathogenic	0.69
BRCA1	P38398-1.2	D749Y	Neutral	0.493
BRCA1	P38398-1.2	L750A	Neutral	0.267
BRCA1	P38398-1.2	L750C	Neutral	0.195
BRCA1	P38398-1.2	L750D	Neutral	0.384
BRCA1	P38398-1.2	L750E	Neutral	0.225
BRCA1	P38398-1.2	L750F	Neutral	0.085
BRCA1	P38398-1.2	L750G	Pathogenic	0.622
BRCA1	P38398-1.2	L750H	Neutral	0.195
BRCA1	P38398-1.2	L750I	Neutral	0.034
BRCA1	P38398-1.2	L750K	Neutral	0.155
BRCA1	P38398-1.2	L750M	Neutral	0.034
BRCA1	P38398-1.2	L750N	Neutral	0.28
BRCA1	P38398-1.2	L750P	Neutral	0.313
BRCA1	P38398-1.2	L750Q	Neutral	0.154
BRCA1	P38398-1.2	L750R	Neutral	0.197
BRCA1	P38398-1.2	L750S	Neutral	0.313
BRCA1	P38398-1.2	L750T	Neutral	0.169
BRCA1	P38398-1.2	L750V	Neutral	0.071
BRCA1	P38398-1.2	L750W	Neutral	0.263
BRCA1	P38398-1.2	L750Y	Neutral	0.132
BRCA1	P38398-1.2	M751A	Neutral	0.006
BRCA1	P38398-1.2	M751C	Neutral	0.004
BRCA1	P38398-1.2	M751D	Neutral	0.007
BRCA1	P38398-1.2	M751E	Neutral	0.003
BRCA1	P38398-1.2	M751F	Neutral	0.002
BRCA1	P38398-1.2	M751G	Neutral	0.019
BRCA1	P38398-1.2	M751H	Neutral	0.003
BRCA1	P38398-1.2	M751I	Neutral	0.001
BRCA1	P38398-1.2	M751K	Neutral	0.002
BRCA1	P38398-1.2	M751L	Neutral	0.001
BRCA1	P38398-1.2	M751N	Neutral	0.005
BRCA1	P38398-1.2	M751P	Neutral	0.005
BRCA1	P38398-1.2	M751Q	Neutral	0.001
BRCA1	P38398-1.2	M751R	Neutral	0.003
BRCA1	P38398-1.2	M751S	Neutral	0.005
BRCA1	P38398-1.2	M751T	Neutral	0.003
BRCA1	P38398-1.2	M751V	Neutral	0.001
BRCA1	P38398-1.2	M751W	Neutral	0.004
BRCA1	P38398-1.2	M751Y	Neutral	0.003
BRCA1	P38398-1.2	L752A	Pathogenic	0.708
BRCA1	P38398-1.2	L752C	Pathogenic	0.617
BRCA1	P38398-1.2	L752D	Pathogenic	0.806
BRCA1	P38398-1.2	L752E	Pathogenic	0.66
BRCA1	P38398-1.2	L752F	Neutral	0.384
BRCA1	P38398-1.2	L752G	Pathogenic	0.916
BRCA1	P38398-1.2	L752H	Pathogenic	0.618
BRCA1	P38398-1.2	L752I	Neutral	0.191
BRCA1	P38398-1.2	L752K	Pathogenic	0.551
BRCA1	P38398-1.2	L752M	Neutral	0.19
BRCA1	P38398-1.2	L752N	Pathogenic	0.722
BRCA1	P38398-1.2	L752P	Pathogenic	0.753
BRCA1	P38398-1.2	L752Q	Pathogenic	0.549
BRCA1	P38398-1.2	L752R	Pathogenic	0.621
BRCA1	P38398-1.2	L752S	Pathogenic	0.752
BRCA1	P38398-1.2	L752T	Pathogenic	0.577
BRCA1	P38398-1.2	L752V	Neutral	0.339
BRCA1	P38398-1.2	L752W	Pathogenic	0.704
BRCA1	P38398-1.2	L752Y	Pathogenic	0.503
BRCA1	P38398-1.2	S753A	Neutral	0.036
BRCA1	P38398-1.2	S753C	Neutral	0.082
BRCA1	P38398-1.2	S753D	Neutral	0.065
BRCA1	P38398-1.2	S753E	Neutral	0.094
BRCA1	P38398-1.2	S753F	Neutral	0.273
BRCA1	P38398-1.2	S753G	Neutral	0.076
BRCA1	P38398-1.2	S753H	Neutral	0.156
BRCA1	P38398-1.2	S753I	Neutral	0.227
BRCA1	P38398-1.2	S753K	Neutral	0.155
BRCA1	P38398-1.2	S753L	Neutral	0.227
BRCA1	P38398-1.2	S753M	Neutral	0.171
BRCA1	P38398-1.2	S753N	Neutral	0.051
BRCA1	P38398-1.2	S753P	Neutral	0.089
BRCA1	P38398-1.2	S753Q	Neutral	0.105
BRCA1	P38398-1.2	S753R	Neutral	0.261
BRCA1	P38398-1.2	S753T	Neutral	0.048
BRCA1	P38398-1.2	S753V	Neutral	0.163
BRCA1	P38398-1.2	S753W	Neutral	0.499
BRCA1	P38398-1.2	S753Y	Neutral	0.303
BRCA1	P38398-1.2	G754A	Pathogenic	0.721
BRCA1	P38398-1.2	G754C	Pathogenic	0.921
BRCA1	P38398-1.2	G754D	Pathogenic	0.863
BRCA1	P38398-1.2	G754E	Pathogenic	0.931
BRCA1	P38398-1.2	G754F	Pathogenic	0.971
BRCA1	P38398-1.2	G754H	Pathogenic	0.943
BRCA1	P38398-1.2	G754I	Pathogenic	0.975
BRCA1	P38398-1.2	G754K	Pathogenic	0.96
BRCA1	P38398-1.2	G754L	Pathogenic	0.975
BRCA1	P38398-1.2	G754M	Pathogenic	0.964
BRCA1	P38398-1.2	G754N	Pathogenic	0.83
BRCA1	P38398-1.2	G754P	Pathogenic	0.899
BRCA1	P38398-1.2	G754Q	Pathogenic	0.938
BRCA1	P38398-1.2	G754R	Pathogenic	0.97
BRCA1	P38398-1.2	G754S	Pathogenic	0.748
BRCA1	P38398-1.2	G754T	Pathogenic	0.905
BRCA1	P38398-1.2	G754V	Pathogenic	0.946
BRCA1	P38398-1.2	G754W	Pathogenic	0.978
BRCA1	P38398-1.2	G754Y	Pathogenic	0.975
BRCA1	P38398-1.2	E755A	Neutral	0.256
BRCA1	P38398-1.2	E755C	Neutral	0.398
BRCA1	P38398-1.2	E755D	Neutral	0.064
BRCA1	P38398-1.2	E755F	Neutral	0.326
BRCA1	P38398-1.2	E755G	Neutral	0.431
BRCA1	P38398-1.2	E755H	Neutral	0.103
BRCA1	P38398-1.2	E755I	Neutral	0.275
BRCA1	P38398-1.2	E755K	Neutral	0.105
BRCA1	P38398-1.2	E755L	Neutral	0.275
BRCA1	P38398-1.2	E755M	Neutral	0.21
BRCA1	P38398-1.2	E755N	Neutral	0.113
BRCA1	P38398-1.2	E755P	Neutral	0.17
BRCA1	P38398-1.2	E755Q	Neutral	0.049
BRCA1	P38398-1.2	E755R	Neutral	0.184
BRCA1	P38398-1.2	E755S	Neutral	0.174
BRCA1	P38398-1.2	E755T	Neutral	0.162
BRCA1	P38398-1.2	E755V	Neutral	0.173
BRCA1	P38398-1.2	E755W	Neutral	0.472
BRCA1	P38398-1.2	E755Y	Neutral	0.281
BRCA1	P38398-1.2	R756A	Neutral	0.336
BRCA1	P38398-1.2	R756C	Neutral	0.404
BRCA1	P38398-1.2	R756D	Neutral	0.304
BRCA1	P38398-1.2	R756E	Neutral	0.124
BRCA1	P38398-1.2	R756F	Neutral	0.184
BRCA1	P38398-1.2	R756G	Pathogenic	0.528
BRCA1	P38398-1.2	R756H	Neutral	0.102
BRCA1	P38398-1.2	R756I	Neutral	0.223
BRCA1	P38398-1.2	R756K	Neutral	0.037
BRCA1	P38398-1.2	R756L	Neutral	0.167
BRCA1	P38398-1.2	R756M	Neutral	0.123
BRCA1	P38398-1.2	R756N	Neutral	0.158
BRCA1	P38398-1.2	R756P	Neutral	0.303
BRCA1	P38398-1.2	R756Q	Neutral	0.08
BRCA1	P38398-1.2	R756S	Neutral	0.309
BRCA1	P38398-1.2	R756T	Neutral	0.222
BRCA1	P38398-1.2	R756V	Neutral	0.307
BRCA1	P38398-1.2	R756W	Neutral	0.189
BRCA1	P38398-1.2	R756Y	Neutral	0.122
BRCA1	P38398-1.2	V757A	Neutral	0.01
BRCA1	P38398-1.2	V757C	Neutral	0.01
BRCA1	P38398-1.2	V757D	Neutral	0.017
BRCA1	P38398-1.2	V757E	Neutral	0.01
BRCA1	P38398-1.2	V757F	Neutral	0.012
BRCA1	P38398-1.2	V757G	Neutral	0.045
BRCA1	P38398-1.2	V757H	Neutral	0.017
BRCA1	P38398-1.2	V757I	Neutral	0.002
BRCA1	P38398-1.2	V757K	Neutral	0.017
BRCA1	P38398-1.2	V757L	Neutral	0.005
BRCA1	P38398-1.2	V757M	Neutral	0.005
BRCA1	P38398-1.2	V757N	Neutral	0.016
BRCA1	P38398-1.2	V757P	Neutral	0.013
BRCA1	P38398-1.2	V757Q	Neutral	0.011
BRCA1	P38398-1.2	V757R	Neutral	0.033
BRCA1	P38398-1.2	V757S	Neutral	0.018
BRCA1	P38398-1.2	V757T	Neutral	0.006
BRCA1	P38398-1.2	V757W	Neutral	0.046
BRCA1	P38398-1.2	V757Y	Neutral	0.014
BRCA1	P38398-1.2	L758A	Neutral	0.363
BRCA1	P38398-1.2	L758C	Neutral	0.274
BRCA1	P38398-1.2	L758D	Neutral	0.493
BRCA1	P38398-1.2	L758E	Neutral	0.313
BRCA1	P38398-1.2	L758F	Neutral	0.127
BRCA1	P38398-1.2	L758G	Pathogenic	0.72
BRCA1	P38398-1.2	L758H	Neutral	0.274
BRCA1	P38398-1.2	L758I	Neutral	0.052
BRCA1	P38398-1.2	L758K	Neutral	0.223
BRCA1	P38398-1.2	L758M	Neutral	0.052
BRCA1	P38398-1.2	L758N	Neutral	0.378
BRCA1	P38398-1.2	L758P	Neutral	0.416
BRCA1	P38398-1.2	L758Q	Neutral	0.222
BRCA1	P38398-1.2	L758R	Neutral	0.277
BRCA1	P38398-1.2	L758S	Neutral	0.416
BRCA1	P38398-1.2	L758T	Neutral	0.242
BRCA1	P38398-1.2	L758V	Neutral	0.107
BRCA1	P38398-1.2	L758W	Neutral	0.358
BRCA1	P38398-1.2	L758Y	Neutral	0.192
BRCA1	P38398-1.2	Q759A	Pathogenic	0.915
BRCA1	P38398-1.2	Q759C	Pathogenic	0.935
BRCA1	P38398-1.2	Q759D	Pathogenic	0.814
BRCA1	P38398-1.2	Q759E	Pathogenic	0.587
BRCA1	P38398-1.2	Q759F	Pathogenic	0.924
BRCA1	P38398-1.2	Q759G	Pathogenic	0.96
BRCA1	P38398-1.2	Q759H	Pathogenic	0.743
BRCA1	P38398-1.2	Q759I	Pathogenic	0.905
BRCA1	P38398-1.2	Q759K	Pathogenic	0.744
BRCA1	P38398-1.2	Q759L	Pathogenic	0.869
BRCA1	P38398-1.2	Q759M	Pathogenic	0.764
BRCA1	P38398-1.2	Q759N	Pathogenic	0.798
BRCA1	P38398-1.2	Q759P	Pathogenic	0.865
BRCA1	P38398-1.2	Q759R	Pathogenic	0.795
BRCA1	P38398-1.2	Q759S	Pathogenic	0.868
BRCA1	P38398-1.2	Q759T	Pathogenic	0.858
BRCA1	P38398-1.2	Q759V	Pathogenic	0.867
BRCA1	P38398-1.2	Q759W	Pathogenic	0.94
BRCA1	P38398-1.2	Q759Y	Pathogenic	0.872
BRCA1	P38398-1.2	T760A	Neutral	0.047
BRCA1	P38398-1.2	T760C	Neutral	0.044
BRCA1	P38398-1.2	T760D	Neutral	0.039
BRCA1	P38398-1.2	T760E	Neutral	0.053
BRCA1	P38398-1.2	T760F	Neutral	0.123
BRCA1	P38398-1.2	T760G	Neutral	0.134
BRCA1	P38398-1.2	T760H	Neutral	0.09
BRCA1	P38398-1.2	T760I	Neutral	0.071
BRCA1	P38398-1.2	T760K	Neutral	0.09
BRCA1	P38398-1.2	T760L	Neutral	0.071
BRCA1	P38398-1.2	T760M	Neutral	0.072
BRCA1	P38398-1.2	T760N	Neutral	0.028
BRCA1	P38398-1.2	T760P	Neutral	0.04
BRCA1	P38398-1.2	T760Q	Neutral	0.059
BRCA1	P38398-1.2	T760R	Neutral	0.116
BRCA1	P38398-1.2	T760S	Neutral	0.029
BRCA1	P38398-1.2	T760V	Neutral	0.034
BRCA1	P38398-1.2	T760W	Neutral	0.206
BRCA1	P38398-1.2	T760Y	Neutral	0.14
BRCA1	P38398-1.2	E761A	Neutral	0.161
BRCA1	P38398-1.2	E761C	Neutral	0.27
BRCA1	P38398-1.2	E761D	Neutral	0.037
BRCA1	P38398-1.2	E761F	Neutral	0.213
BRCA1	P38398-1.2	E761G	Neutral	0.297
BRCA1	P38398-1.2	E761H	Neutral	0.06
BRCA1	P38398-1.2	E761I	Neutral	0.175
BRCA1	P38398-1.2	E761K	Neutral	0.062
BRCA1	P38398-1.2	E761L	Neutral	0.175
BRCA1	P38398-1.2	E761M	Neutral	0.129
BRCA1	P38398-1.2	E761N	Neutral	0.066
BRCA1	P38398-1.2	E761P	Neutral	0.102
BRCA1	P38398-1.2	E761Q	Neutral	0.028
BRCA1	P38398-1.2	E761R	Neutral	0.112
BRCA1	P38398-1.2	E761S	Neutral	0.105
BRCA1	P38398-1.2	E761T	Neutral	0.097
BRCA1	P38398-1.2	E761V	Neutral	0.104
BRCA1	P38398-1.2	E761W	Neutral	0.333
BRCA1	P38398-1.2	E761Y	Neutral	0.179
BRCA1	P38398-1.2	R762A	Pathogenic	0.959
BRCA1	P38398-1.2	R762C	Pathogenic	0.969
BRCA1	P38398-1.2	R762D	Pathogenic	0.953
BRCA1	P38398-1.2	R762E	Pathogenic	0.866
BRCA1	P38398-1.2	R762F	Pathogenic	0.912
BRCA1	P38398-1.2	R762G	Pathogenic	0.981
BRCA1	P38398-1.2	R762H	Pathogenic	0.839
BRCA1	P38398-1.2	R762I	Pathogenic	0.93
BRCA1	P38398-1.2	R762K	Pathogenic	0.639
BRCA1	P38398-1.2	R762L	Pathogenic	0.902
BRCA1	P38398-1.2	R762M	Pathogenic	0.866
BRCA1	P38398-1.2	R762N	Pathogenic	0.896
BRCA1	P38398-1.2	R762P	Pathogenic	0.952
BRCA1	P38398-1.2	R762Q	Pathogenic	0.8
BRCA1	P38398-1.2	R762S	Pathogenic	0.954
BRCA1	P38398-1.2	R762T	Pathogenic	0.929
BRCA1	P38398-1.2	R762V	Pathogenic	0.953
BRCA1	P38398-1.2	R762W	Pathogenic	0.915
BRCA1	P38398-1.2	R762Y	Pathogenic	0.865
BRCA1	P38398-1.2	S763A	Pathogenic	0.629
BRCA1	P38398-1.2	S763C	Pathogenic	0.802
BRCA1	P38398-1.2	S763D	Pathogenic	0.759
BRCA1	P38398-1.2	S763E	Pathogenic	0.825
BRCA1	P38398-1.2	S763F	Pathogenic	0.944
BRCA1	P38398-1.2	S763G	Pathogenic	0.789
BRCA1	P38398-1.2	S763H	Pathogenic	0.893
BRCA1	P38398-1.2	S763I	Pathogenic	0.93
BRCA1	P38398-1.2	S763K	Pathogenic	0.893
BRCA1	P38398-1.2	S763L	Pathogenic	0.93
BRCA1	P38398-1.2	S763M	Pathogenic	0.903
BRCA1	P38398-1.2	S763N	Pathogenic	0.711
BRCA1	P38398-1.2	S763P	Pathogenic	0.816
BRCA1	P38398-1.2	S763Q	Pathogenic	0.842
BRCA1	P38398-1.2	S763R	Pathogenic	0.941
BRCA1	P38398-1.2	S763T	Pathogenic	0.698
BRCA1	P38398-1.2	S763V	Pathogenic	0.898
BRCA1	P38398-1.2	S763W	Pathogenic	0.978
BRCA1	P38398-1.2	S763Y	Pathogenic	0.952
BRCA1	P38398-1.2	V764A	Neutral	0.002
BRCA1	P38398-1.2	V764C	Neutral	0.002
BRCA1	P38398-1.2	V764D	Neutral	0.004
BRCA1	P38398-1.2	V764E	Neutral	0.002
BRCA1	P38398-1.2	V764F	Neutral	0.003
BRCA1	P38398-1.2	V764G	Neutral	0.011
BRCA1	P38398-1.2	V764H	Neutral	0.004
BRCA1	P38398-1.2	V764I	Neutral	0.001
BRCA1	P38398-1.2	V764K	Neutral	0.004
BRCA1	P38398-1.2	V764L	Neutral	0.001
BRCA1	P38398-1.2	V764M	Neutral	0.001
BRCA1	P38398-1.2	V764N	Neutral	0.004
BRCA1	P38398-1.2	V764P	Neutral	0.003
BRCA1	P38398-1.2	V764Q	Neutral	0.003
BRCA1	P38398-1.2	V764R	Neutral	0.008
BRCA1	P38398-1.2	V764S	Neutral	0.004
BRCA1	P38398-1.2	V764T	Neutral	0.001
BRCA1	P38398-1.2	V764W	Neutral	0.011
BRCA1	P38398-1.2	V764Y	Neutral	0.003
BRCA1	P38398-1.2	E765A	Pathogenic	0.892
BRCA1	P38398-1.2	E765C	Pathogenic	0.941
BRCA1	P38398-1.2	E765D	Pathogenic	0.623
BRCA1	P38398-1.2	E765F	Pathogenic	0.921
BRCA1	P38398-1.2	E765G	Pathogenic	0.948
BRCA1	P38398-1.2	E765H	Pathogenic	0.734
BRCA1	P38398-1.2	E765I	Pathogenic	0.901
BRCA1	P38398-1.2	E765K	Pathogenic	0.739
BRCA1	P38398-1.2	E765L	Pathogenic	0.901
BRCA1	P38398-1.2	E765M	Pathogenic	0.865
BRCA1	P38398-1.2	E765N	Pathogenic	0.754
BRCA1	P38398-1.2	E765P	Pathogenic	0.831
BRCA1	P38398-1.2	E765Q	Pathogenic	0.552
BRCA1	P38398-1.2	E765R	Pathogenic	0.844
BRCA1	P38398-1.2	E765S	Pathogenic	0.835
BRCA1	P38398-1.2	E765T	Pathogenic	0.823
BRCA1	P38398-1.2	E765V	Pathogenic	0.834
BRCA1	P38398-1.2	E765W	Pathogenic	0.956
BRCA1	P38398-1.2	E765Y	Pathogenic	0.904
BRCA1	P38398-1.2	S766A	Pathogenic	0.641
BRCA1	P38398-1.2	S766C	Pathogenic	0.81
BRCA1	P38398-1.2	S766D	Pathogenic	0.769
BRCA1	P38398-1.2	S766E	Pathogenic	0.833
BRCA1	P38398-1.2	S766F	Pathogenic	0.947
BRCA1	P38398-1.2	S766G	Pathogenic	0.797
BRCA1	P38398-1.2	S766H	Pathogenic	0.898
BRCA1	P38398-1.2	S766I	Pathogenic	0.933
BRCA1	P38398-1.2	S766K	Pathogenic	0.898
BRCA1	P38398-1.2	S766L	Pathogenic	0.934
BRCA1	P38398-1.2	S766M	Pathogenic	0.908
BRCA1	P38398-1.2	S766N	Pathogenic	0.722
BRCA1	P38398-1.2	S766P	Pathogenic	0.824
BRCA1	P38398-1.2	S766Q	Pathogenic	0.849
BRCA1	P38398-1.2	S766R	Pathogenic	0.944
BRCA1	P38398-1.2	S766T	Pathogenic	0.709
BRCA1	P38398-1.2	S766V	Pathogenic	0.903
BRCA1	P38398-1.2	S766W	Pathogenic	0.979
BRCA1	P38398-1.2	S766Y	Pathogenic	0.954
BRCA1	P38398-1.2	S767A	Neutral	0.087
BRCA1	P38398-1.2	S767C	Neutral	0.186
BRCA1	P38398-1.2	S767D	Neutral	0.151
BRCA1	P38398-1.2	S767E	Neutral	0.21
BRCA1	P38398-1.2	S767F	Neutral	0.49
BRCA1	P38398-1.2	S767G	Neutral	0.174
BRCA1	P38398-1.2	S767H	Neutral	0.32
BRCA1	P38398-1.2	S767I	Neutral	0.429
BRCA1	P38398-1.2	S767K	Neutral	0.32
BRCA1	P38398-1.2	S767L	Neutral	0.429
BRCA1	P38398-1.2	S767M	Neutral	0.345
BRCA1	P38398-1.2	S767N	Neutral	0.122
BRCA1	P38398-1.2	S767P	Neutral	0.2
BRCA1	P38398-1.2	S767Q	Neutral	0.231
BRCA1	P38398-1.2	S767R	Neutral	0.475
BRCA1	P38398-1.2	S767T	Neutral	0.115
BRCA1	P38398-1.2	S767V	Neutral	0.332
BRCA1	P38398-1.2	S767W	Pathogenic	0.718
BRCA1	P38398-1.2	S767Y	Pathogenic	0.527
BRCA1	P38398-1.2	S768A	Neutral	0.082
BRCA1	P38398-1.2	S768C	Neutral	0.175
BRCA1	P38398-1.2	S768D	Neutral	0.142
BRCA1	P38398-1.2	S768E	Neutral	0.199
BRCA1	P38398-1.2	S768F	Neutral	0.472
BRCA1	P38398-1.2	S768G	Neutral	0.164
BRCA1	P38398-1.2	S768H	Neutral	0.305
BRCA1	P38398-1.2	S768I	Neutral	0.412
BRCA1	P38398-1.2	S768K	Neutral	0.305
BRCA1	P38398-1.2	S768L	Neutral	0.412
BRCA1	P38398-1.2	S768M	Neutral	0.33
BRCA1	P38398-1.2	S768N	Neutral	0.114
BRCA1	P38398-1.2	S768P	Neutral	0.189
BRCA1	P38398-1.2	S768Q	Neutral	0.218
BRCA1	P38398-1.2	S768R	Neutral	0.457
BRCA1	P38398-1.2	S768T	Neutral	0.108
BRCA1	P38398-1.2	S768V	Neutral	0.317
BRCA1	P38398-1.2	S768W	Pathogenic	0.704
BRCA1	P38398-1.2	S768Y	Pathogenic	0.509
BRCA1	P38398-1.2	I769A	Neutral	0.296
BRCA1	P38398-1.2	I769C	Neutral	0.218
BRCA1	P38398-1.2	I769D	Neutral	0.333
BRCA1	P38398-1.2	I769E	Neutral	0.251
BRCA1	P38398-1.2	I769F	Neutral	0.097
BRCA1	P38398-1.2	I769G	Pathogenic	0.655
BRCA1	P38398-1.2	I769H	Neutral	0.218
BRCA1	P38398-1.2	I769K	Neutral	0.234
BRCA1	P38398-1.2	I769L	Neutral	0.039
BRCA1	P38398-1.2	I769M	Neutral	0.055
BRCA1	P38398-1.2	I769N	Neutral	0.31
BRCA1	P38398-1.2	I769P	Neutral	0.344
BRCA1	P38398-1.2	I769Q	Neutral	0.232
BRCA1	P38398-1.2	I769R	Neutral	0.289
BRCA1	P38398-1.2	I769S	Neutral	0.344
BRCA1	P38398-1.2	I769T	Neutral	0.19
BRCA1	P38398-1.2	I769V	Neutral	0.041
BRCA1	P38398-1.2	I769W	Neutral	0.373
BRCA1	P38398-1.2	I769Y	Neutral	0.149
BRCA1	P38398-1.2	S770A	Neutral	0.207
BRCA1	P38398-1.2	S770C	Neutral	0.384
BRCA1	P38398-1.2	S770D	Neutral	0.328
BRCA1	P38398-1.2	S770E	Neutral	0.422
BRCA1	P38398-1.2	S770F	Pathogenic	0.724
BRCA1	P38398-1.2	S770G	Neutral	0.366
BRCA1	P38398-1.2	S770H	Pathogenic	0.564
BRCA1	P38398-1.2	S770I	Pathogenic	0.673
BRCA1	P38398-1.2	S770K	Pathogenic	0.563
BRCA1	P38398-1.2	S770L	Pathogenic	0.673
BRCA1	P38398-1.2	S770M	Pathogenic	0.591
BRCA1	P38398-1.2	S770N	Neutral	0.275
BRCA1	P38398-1.2	S770P	Neutral	0.407
BRCA1	P38398-1.2	S770Q	Neutral	0.451
BRCA1	P38398-1.2	S770R	Pathogenic	0.712
BRCA1	P38398-1.2	S770T	Neutral	0.263
BRCA1	P38398-1.2	S770V	Pathogenic	0.577
BRCA1	P38398-1.2	S770W	Pathogenic	0.875
BRCA1	P38398-1.2	S770Y	Pathogenic	0.753
BRCA1	P38398-1.2	L771A	Pathogenic	0.862
BRCA1	P38398-1.2	L771C	Pathogenic	0.806
BRCA1	P38398-1.2	L771D	Pathogenic	0.915
BRCA1	P38398-1.2	L771E	Pathogenic	0.834
BRCA1	P38398-1.2	L771F	Pathogenic	0.616
BRCA1	P38398-1.2	L771G	Pathogenic	0.966
BRCA1	P38398-1.2	L771H	Pathogenic	0.806
BRCA1	P38398-1.2	L771I	Neutral	0.378
BRCA1	P38398-1.2	L771K	Pathogenic	0.76
BRCA1	P38398-1.2	L771M	Neutral	0.376
BRCA1	P38398-1.2	L771N	Pathogenic	0.87
BRCA1	P38398-1.2	L771P	Pathogenic	0.887
BRCA1	P38398-1.2	L771Q	Pathogenic	0.759
BRCA1	P38398-1.2	L771R	Pathogenic	0.809
BRCA1	P38398-1.2	L771S	Pathogenic	0.887
BRCA1	P38398-1.2	L771T	Pathogenic	0.778
BRCA1	P38398-1.2	L771V	Pathogenic	0.57
BRCA1	P38398-1.2	L771W	Pathogenic	0.86
BRCA1	P38398-1.2	L771Y	Pathogenic	0.723
BRCA1	P38398-1.2	V772A	Pathogenic	0.88
BRCA1	P38398-1.2	V772C	Pathogenic	0.875
BRCA1	P38398-1.2	V772D	Pathogenic	0.926
BRCA1	P38398-1.2	V772E	Pathogenic	0.875
BRCA1	P38398-1.2	V772F	Pathogenic	0.899
BRCA1	P38398-1.2	V772G	Pathogenic	0.971
BRCA1	P38398-1.2	V772H	Pathogenic	0.926
BRCA1	P38398-1.2	V772I	Pathogenic	0.618
BRCA1	P38398-1.2	V772K	Pathogenic	0.925
BRCA1	P38398-1.2	V772L	Pathogenic	0.77
BRCA1	P38398-1.2	V772M	Pathogenic	0.772
BRCA1	P38398-1.2	V772N	Pathogenic	0.918
BRCA1	P38398-1.2	V772P	Pathogenic	0.901
BRCA1	P38398-1.2	V772Q	Pathogenic	0.887
BRCA1	P38398-1.2	V772R	Pathogenic	0.96
BRCA1	P38398-1.2	V772S	Pathogenic	0.929
BRCA1	P38398-1.2	V772T	Pathogenic	0.804
BRCA1	P38398-1.2	V772W	Pathogenic	0.971
BRCA1	P38398-1.2	V772Y	Pathogenic	0.911
BRCA1	P38398-1.2	P773A	Pathogenic	0.962
BRCA1	P38398-1.2	P773C	Pathogenic	0.972
BRCA1	P38398-1.2	P773D	Pathogenic	0.938
BRCA1	P38398-1.2	P773E	Pathogenic	0.958
BRCA1	P38398-1.2	P773F	Pathogenic	0.992
BRCA1	P38398-1.2	P773G	Pathogenic	0.982
BRCA1	P38398-1.2	P773H	Pathogenic	0.976
BRCA1	P38398-1.2	P773I	Pathogenic	0.985
BRCA1	P38398-1.2	P773K	Pathogenic	0.976
BRCA1	P38398-1.2	P773L	Pathogenic	0.985
BRCA1	P38398-1.2	P773M	Pathogenic	0.979
BRCA1	P38398-1.2	P773N	Pathogenic	0.961
BRCA1	P38398-1.2	P773Q	Pathogenic	0.962
BRCA1	P38398-1.2	P773R	Pathogenic	0.987
BRCA1	P38398-1.2	P773S	Pathogenic	0.957
BRCA1	P38398-1.2	P773T	Pathogenic	0.942
BRCA1	P38398-1.2	P773V	Pathogenic	0.968
BRCA1	P38398-1.2	P773W	Pathogenic	0.996
BRCA1	P38398-1.2	P773Y	Pathogenic	0.99
BRCA1	P38398-1.2	G774A	Neutral	0.169
BRCA1	P38398-1.2	G774C	Neutral	0.478
BRCA1	P38398-1.2	G774D	Neutral	0.331
BRCA1	P38398-1.2	G774E	Pathogenic	0.516
BRCA1	P38398-1.2	G774F	Pathogenic	0.728
BRCA1	P38398-1.2	G774H	Pathogenic	0.568
BRCA1	P38398-1.2	G774I	Pathogenic	0.751
BRCA1	P38398-1.2	G774K	Pathogenic	0.653
BRCA1	P38398-1.2	G774L	Pathogenic	0.751
BRCA1	P38398-1.2	G774M	Pathogenic	0.679
BRCA1	P38398-1.2	G774N	Neutral	0.278
BRCA1	P38398-1.2	G774P	Neutral	0.411
BRCA1	P38398-1.2	G774Q	Pathogenic	0.546
BRCA1	P38398-1.2	G774R	Pathogenic	0.716
BRCA1	P38398-1.2	G774S	Neutral	0.19
BRCA1	P38398-1.2	G774T	Neutral	0.429
BRCA1	P38398-1.2	G774V	Pathogenic	0.581
BRCA1	P38398-1.2	G774W	Pathogenic	0.774
BRCA1	P38398-1.2	G774Y	Pathogenic	0.756
BRCA1	P38398-1.2	T775A	Pathogenic	0.958
BRCA1	P38398-1.2	T775C	Pathogenic	0.955
BRCA1	P38398-1.2	T775D	Pathogenic	0.95
BRCA1	P38398-1.2	T775E	Pathogenic	0.963
BRCA1	P38398-1.2	T775F	Pathogenic	0.985
BRCA1	P38398-1.2	T775G	Pathogenic	0.986
BRCA1	P38398-1.2	T775H	Pathogenic	0.979
BRCA1	P38398-1.2	T775I	Pathogenic	0.973
BRCA1	P38398-1.2	T775K	Pathogenic	0.979
BRCA1	P38398-1.2	T775L	Pathogenic	0.973
BRCA1	P38398-1.2	T775M	Pathogenic	0.973
BRCA1	P38398-1.2	T775N	Pathogenic	0.931
BRCA1	P38398-1.2	T775P	Pathogenic	0.951
BRCA1	P38398-1.2	T775Q	Pathogenic	0.967
BRCA1	P38398-1.2	T775R	Pathogenic	0.984
BRCA1	P38398-1.2	T775S	Pathogenic	0.932
BRCA1	P38398-1.2	T775V	Pathogenic	0.943
BRCA1	P38398-1.2	T775W	Pathogenic	0.992
BRCA1	P38398-1.2	T775Y	Pathogenic	0.987
BRCA1	P38398-1.2	D776A	Pathogenic	0.973
BRCA1	P38398-1.2	D776C	Pathogenic	0.971
BRCA1	P38398-1.2	D776E	Pathogenic	0.882
BRCA1	P38398-1.2	D776F	Pathogenic	0.987
BRCA1	P38398-1.2	D776G	Pathogenic	0.975
BRCA1	P38398-1.2	D776H	Pathogenic	0.964
BRCA1	P38398-1.2	D776I	Pathogenic	0.984
BRCA1	P38398-1.2	D776K	Pathogenic	0.975
BRCA1	P38398-1.2	D776L	Pathogenic	0.989
BRCA1	P38398-1.2	D776M	Pathogenic	0.984
BRCA1	P38398-1.2	D776N	Pathogenic	0.89
BRCA1	P38398-1.2	D776P	Pathogenic	0.937
BRCA1	P38398-1.2	D776Q	Pathogenic	0.945
BRCA1	P38398-1.2	D776R	Pathogenic	0.987
BRCA1	P38398-1.2	D776S	Pathogenic	0.939
BRCA1	P38398-1.2	D776T	Pathogenic	0.939
BRCA1	P38398-1.2	D776V	Pathogenic	0.976
BRCA1	P38398-1.2	D776W	Pathogenic	0.995
BRCA1	P38398-1.2	D776Y	Pathogenic	0.989
BRCA1	P38398-1.2	Y777A	Pathogenic	0.868
BRCA1	P38398-1.2	Y777C	Pathogenic	0.814
BRCA1	P38398-1.2	Y777D	Pathogenic	0.845
BRCA1	P38398-1.2	Y777E	Pathogenic	0.718
BRCA1	P38398-1.2	Y777F	Neutral	0.191
BRCA1	P38398-1.2	Y777G	Pathogenic	0.935
BRCA1	P38398-1.2	Y777H	Neutral	0.331
BRCA1	P38398-1.2	Y777I	Pathogenic	0.563
BRCA1	P38398-1.2	Y777K	Pathogenic	0.587
BRCA1	P38398-1.2	Y777L	Pathogenic	0.564
BRCA1	P38398-1.2	Y777M	Pathogenic	0.566
BRCA1	P38398-1.2	Y777N	Pathogenic	0.773
BRCA1	P38398-1.2	Y777P	Pathogenic	0.852
BRCA1	P38398-1.2	Y777Q	Pathogenic	0.615
BRCA1	P38398-1.2	Y777R	Pathogenic	0.592
BRCA1	P38398-1.2	Y777S	Pathogenic	0.852
BRCA1	P38398-1.2	Y777T	Pathogenic	0.787
BRCA1	P38398-1.2	Y777V	Pathogenic	0.665
BRCA1	P38398-1.2	Y777W	Neutral	0.324
BRCA1	P38398-1.2	G778A	Neutral	0.162
BRCA1	P38398-1.2	G778C	Neutral	0.465
BRCA1	P38398-1.2	G778D	Neutral	0.32
BRCA1	P38398-1.2	G778E	Pathogenic	0.503
BRCA1	P38398-1.2	G778F	Pathogenic	0.718
BRCA1	P38398-1.2	G778H	Pathogenic	0.556
BRCA1	P38398-1.2	G778I	Pathogenic	0.741
BRCA1	P38398-1.2	G778K	Pathogenic	0.642
BRCA1	P38398-1.2	G778L	Pathogenic	0.742
BRCA1	P38398-1.2	G778M	Pathogenic	0.668
BRCA1	P38398-1.2	G778N	Neutral	0.268
BRCA1	P38398-1.2	G778P	Neutral	0.399
BRCA1	P38398-1.2	G778Q	Pathogenic	0.533
BRCA1	P38398-1.2	G778R	Pathogenic	0.705
BRCA1	P38398-1.2	G778S	Neutral	0.182
BRCA1	P38398-1.2	G778T	Neutral	0.417
BRCA1	P38398-1.2	G778V	Pathogenic	0.569
BRCA1	P38398-1.2	G778W	Pathogenic	0.765
BRCA1	P38398-1.2	G778Y	Pathogenic	0.747
BRCA1	P38398-1.2	T779A	Pathogenic	0.806
BRCA1	P38398-1.2	T779C	Pathogenic	0.794
BRCA1	P38398-1.2	T779D	Pathogenic	0.775
BRCA1	P38398-1.2	T779E	Pathogenic	0.825
BRCA1	P38398-1.2	T779F	Pathogenic	0.923
BRCA1	P38398-1.2	T779G	Pathogenic	0.929
BRCA1	P38398-1.2	T779H	Pathogenic	0.894
BRCA1	P38398-1.2	T779I	Pathogenic	0.866
BRCA1	P38398-1.2	T779K	Pathogenic	0.893
BRCA1	P38398-1.2	T779L	Pathogenic	0.867
BRCA1	P38398-1.2	T779M	Pathogenic	0.868
BRCA1	P38398-1.2	T779N	Pathogenic	0.71
BRCA1	P38398-1.2	T779P	Pathogenic	0.78
BRCA1	P38398-1.2	T779Q	Pathogenic	0.841
BRCA1	P38398-1.2	T779R	Pathogenic	0.917
BRCA1	P38398-1.2	T779S	Pathogenic	0.715
BRCA1	P38398-1.2	T779V	Pathogenic	0.749
BRCA1	P38398-1.2	T779W	Pathogenic	0.957
BRCA1	P38398-1.2	T779Y	Pathogenic	0.933
BRCA1	P38398-1.2	Q780A	Pathogenic	0.977
BRCA1	P38398-1.2	Q780C	Pathogenic	0.983
BRCA1	P38398-1.2	Q780D	Pathogenic	0.945
BRCA1	P38398-1.2	Q780E	Pathogenic	0.848
BRCA1	P38398-1.2	Q780F	Pathogenic	0.979
BRCA1	P38398-1.2	Q780G	Pathogenic	0.989
BRCA1	P38398-1.2	Q780H	Pathogenic	0.919
BRCA1	P38398-1.2	Q780I	Pathogenic	0.974
BRCA1	P38398-1.2	Q780K	Pathogenic	0.919
BRCA1	P38398-1.2	Q780L	Pathogenic	0.963
BRCA1	P38398-1.2	Q780M	Pathogenic	0.927
BRCA1	P38398-1.2	Q780N	Pathogenic	0.939
BRCA1	P38398-1.2	Q780P	Pathogenic	0.962
BRCA1	P38398-1.2	Q780R	Pathogenic	0.938
BRCA1	P38398-1.2	Q780S	Pathogenic	0.963
BRCA1	P38398-1.2	Q780T	Pathogenic	0.96
BRCA1	P38398-1.2	Q780V	Pathogenic	0.963
BRCA1	P38398-1.2	Q780W	Pathogenic	0.984
BRCA1	P38398-1.2	Q780Y	Pathogenic	0.964
BRCA1	P38398-1.2	E781A	Neutral	0.13
BRCA1	P38398-1.2	E781C	Neutral	0.223
BRCA1	P38398-1.2	E781D	Neutral	0.029
BRCA1	P38398-1.2	E781F	Neutral	0.174
BRCA1	P38398-1.2	E781G	Neutral	0.248
BRCA1	P38398-1.2	E781H	Neutral	0.048
BRCA1	P38398-1.2	E781I	Neutral	0.141
BRCA1	P38398-1.2	E781K	Neutral	0.049
BRCA1	P38398-1.2	E781L	Neutral	0.142
BRCA1	P38398-1.2	E781M	Neutral	0.104
BRCA1	P38398-1.2	E781N	Neutral	0.052
BRCA1	P38398-1.2	E781P	Neutral	0.082
BRCA1	P38398-1.2	E781Q	Neutral	0.022
BRCA1	P38398-1.2	E781R	Neutral	0.089
BRCA1	P38398-1.2	E781S	Neutral	0.084
BRCA1	P38398-1.2	E781T	Neutral	0.077
BRCA1	P38398-1.2	E781V	Neutral	0.083
BRCA1	P38398-1.2	E781W	Neutral	0.28
BRCA1	P38398-1.2	E781Y	Neutral	0.145
BRCA1	P38398-1.2	S782A	Pathogenic	0.935
BRCA1	P38398-1.2	S782C	Pathogenic	0.972
BRCA1	P38398-1.2	S782D	Pathogenic	0.964
BRCA1	P38398-1.2	S782E	Pathogenic	0.976
BRCA1	P38398-1.2	S782F	Pathogenic	0.993
BRCA1	P38398-1.2	S782G	Pathogenic	0.97
BRCA1	P38398-1.2	S782H	Pathogenic	0.986
BRCA1	P38398-1.2	S782I	Pathogenic	0.991
BRCA1	P38398-1.2	S782K	Pathogenic	0.986
BRCA1	P38398-1.2	S782L	Pathogenic	0.991
BRCA1	P38398-1.2	S782M	Pathogenic	0.988
BRCA1	P38398-1.2	S782N	Pathogenic	0.955
BRCA1	P38398-1.2	S782P	Pathogenic	0.974
BRCA1	P38398-1.2	S782Q	Pathogenic	0.978
BRCA1	P38398-1.2	S782R	Pathogenic	0.993
BRCA1	P38398-1.2	S782T	Pathogenic	0.952
BRCA1	P38398-1.2	S782V	Pathogenic	0.987
BRCA1	P38398-1.2	S782W	Pathogenic	0.997
BRCA1	P38398-1.2	S782Y	Pathogenic	0.994
BRCA1	P38398-1.2	I783A	Neutral	0.123
BRCA1	P38398-1.2	I783C	Neutral	0.086
BRCA1	P38398-1.2	I783D	Neutral	0.144
BRCA1	P38398-1.2	I783E	Neutral	0.101
BRCA1	P38398-1.2	I783F	Neutral	0.035
BRCA1	P38398-1.2	I783G	Neutral	0.389
BRCA1	P38398-1.2	I783H	Neutral	0.086
BRCA1	P38398-1.2	I783K	Neutral	0.093
BRCA1	P38398-1.2	I783L	Neutral	0.013
BRCA1	P38398-1.2	I783M	Neutral	0.019
BRCA1	P38398-1.2	I783N	Neutral	0.131
BRCA1	P38398-1.2	I783P	Neutral	0.15
BRCA1	P38398-1.2	I783Q	Neutral	0.092
BRCA1	P38398-1.2	I783R	Neutral	0.12
BRCA1	P38398-1.2	I783S	Neutral	0.15
BRCA1	P38398-1.2	I783T	Neutral	0.073
BRCA1	P38398-1.2	I783V	Neutral	0.014
BRCA1	P38398-1.2	I783W	Neutral	0.166
BRCA1	P38398-1.2	I783Y	Neutral	0.055
BRCA1	P38398-1.2	S784A	Pathogenic	0.944
BRCA1	P38398-1.2	S784C	Pathogenic	0.976
BRCA1	P38398-1.2	S784D	Pathogenic	0.969
BRCA1	P38398-1.2	S784E	Pathogenic	0.979
BRCA1	P38398-1.2	S784F	Pathogenic	0.994
BRCA1	P38398-1.2	S784G	Pathogenic	0.974
BRCA1	P38398-1.2	S784H	Pathogenic	0.988
BRCA1	P38398-1.2	S784I	Pathogenic	0.993
BRCA1	P38398-1.2	S784K	Pathogenic	0.988
BRCA1	P38398-1.2	S784L	Pathogenic	0.993
BRCA1	P38398-1.2	S784M	Pathogenic	0.989
BRCA1	P38398-1.2	S784N	Pathogenic	0.961
BRCA1	P38398-1.2	S784P	Pathogenic	0.978
BRCA1	P38398-1.2	S784Q	Pathogenic	0.982
BRCA1	P38398-1.2	S784R	Pathogenic	0.994
BRCA1	P38398-1.2	S784T	Pathogenic	0.959
BRCA1	P38398-1.2	S784V	Pathogenic	0.989
BRCA1	P38398-1.2	S784W	Pathogenic	0.998
BRCA1	P38398-1.2	S784Y	Pathogenic	0.995
BRCA1	P38398-1.2	L785A	Pathogenic	0.98
BRCA1	P38398-1.2	L785C	Pathogenic	0.97
BRCA1	P38398-1.2	L785D	Pathogenic	0.988
BRCA1	P38398-1.2	L785E	Pathogenic	0.975
BRCA1	P38398-1.2	L785F	Pathogenic	0.925
BRCA1	P38398-1.2	L785G	Pathogenic	0.995
BRCA1	P38398-1.2	L785H	Pathogenic	0.97
BRCA1	P38398-1.2	L785I	Pathogenic	0.823
BRCA1	P38398-1.2	L785K	Pathogenic	0.96
BRCA1	P38398-1.2	L785M	Pathogenic	0.822
BRCA1	P38398-1.2	L785N	Pathogenic	0.981
BRCA1	P38398-1.2	L785P	Pathogenic	0.984
BRCA1	P38398-1.2	L785Q	Pathogenic	0.96
BRCA1	P38398-1.2	L785R	Pathogenic	0.97
BRCA1	P38398-1.2	L785S	Pathogenic	0.984
BRCA1	P38398-1.2	L785T	Pathogenic	0.964
BRCA1	P38398-1.2	L785V	Pathogenic	0.91
BRCA1	P38398-1.2	L785W	Pathogenic	0.979
BRCA1	P38398-1.2	L785Y	Pathogenic	0.952
BRCA1	P38398-1.2	L786A	Pathogenic	0.982
BRCA1	P38398-1.2	L786C	Pathogenic	0.973
BRCA1	P38398-1.2	L786D	Pathogenic	0.989
BRCA1	P38398-1.2	L786E	Pathogenic	0.978
BRCA1	P38398-1.2	L786F	Pathogenic	0.933
BRCA1	P38398-1.2	L786G	Pathogenic	0.996
BRCA1	P38398-1.2	L786H	Pathogenic	0.973
BRCA1	P38398-1.2	L786I	Pathogenic	0.841
BRCA1	P38398-1.2	L786K	Pathogenic	0.965
BRCA1	P38398-1.2	L786M	Pathogenic	0.84
BRCA1	P38398-1.2	L786N	Pathogenic	0.983
BRCA1	P38398-1.2	L786P	Pathogenic	0.986
BRCA1	P38398-1.2	L786Q	Pathogenic	0.965
BRCA1	P38398-1.2	L786R	Pathogenic	0.974
BRCA1	P38398-1.2	L786S	Pathogenic	0.986
BRCA1	P38398-1.2	L786T	Pathogenic	0.968
BRCA1	P38398-1.2	L786V	Pathogenic	0.92
BRCA1	P38398-1.2	L786W	Pathogenic	0.982
BRCA1	P38398-1.2	L786Y	Pathogenic	0.958
BRCA1	P38398-1.2	E787A	Neutral	0.244
BRCA1	P38398-1.2	E787C	Neutral	0.384
BRCA1	P38398-1.2	E787D	Neutral	0.061
BRCA1	P38398-1.2	E787F	Neutral	0.313
BRCA1	P38398-1.2	E787G	Neutral	0.417
BRCA1	P38398-1.2	E787H	Neutral	0.098
BRCA1	P38398-1.2	E787I	Neutral	0.263
BRCA1	P38398-1.2	E787K	Neutral	0.1
BRCA1	P38398-1.2	E787L	Neutral	0.264
BRCA1	P38398-1.2	E787M	Neutral	0.201
BRCA1	P38398-1.2	E787N	Neutral	0.107
BRCA1	P38398-1.2	E787P	Neutral	0.161
BRCA1	P38398-1.2	E787Q	Neutral	0.046
BRCA1	P38398-1.2	E787R	Neutral	0.175
BRCA1	P38398-1.2	E787S	Neutral	0.165
BRCA1	P38398-1.2	E787T	Neutral	0.154
BRCA1	P38398-1.2	E787V	Neutral	0.164
BRCA1	P38398-1.2	E787W	Neutral	0.457
BRCA1	P38398-1.2	E787Y	Neutral	0.269
BRCA1	P38398-1.2	V788A	Neutral	0.011
BRCA1	P38398-1.2	V788C	Neutral	0.01
BRCA1	P38398-1.2	V788D	Neutral	0.018
BRCA1	P38398-1.2	V788E	Neutral	0.01
BRCA1	P38398-1.2	V788F	Neutral	0.013
BRCA1	P38398-1.2	V788G	Neutral	0.047
BRCA1	P38398-1.2	V788H	Neutral	0.018
BRCA1	P38398-1.2	V788I	Neutral	0.002
BRCA1	P38398-1.2	V788K	Neutral	0.018
BRCA1	P38398-1.2	V788L	Neutral	0.005
BRCA1	P38398-1.2	V788M	Neutral	0.005
BRCA1	P38398-1.2	V788N	Neutral	0.017
BRCA1	P38398-1.2	V788P	Neutral	0.014
BRCA1	P38398-1.2	V788Q	Neutral	0.012
BRCA1	P38398-1.2	V788R	Neutral	0.034
BRCA1	P38398-1.2	V788S	Neutral	0.019
BRCA1	P38398-1.2	V788T	Neutral	0.006
BRCA1	P38398-1.2	V788W	Neutral	0.049
BRCA1	P38398-1.2	V788Y	Neutral	0.015
BRCA1	P38398-1.2	S789A	Neutral	0.002
BRCA1	P38398-1.2	S789C	Neutral	0.004
BRCA1	P38398-1.2	S789D	Neutral	0.003
BRCA1	P38398-1.2	S789E	Neutral	0.005
BRCA1	P38398-1.2	S789F	Neutral	0.018
BRCA1	P38398-1.2	S789G	Neutral	0.004
BRCA1	P38398-1.2	S789H	Neutral	0.009
BRCA1	P38398-1.2	S789I	Neutral	0.014
BRCA1	P38398-1.2	S789K	Neutral	0.009
BRCA1	P38398-1.2	S789L	Neutral	0.014
BRCA1	P38398-1.2	S789M	Neutral	0.01
BRCA1	P38398-1.2	S789N	Neutral	0.003
BRCA1	P38398-1.2	S789P	Neutral	0.005
BRCA1	P38398-1.2	S789Q	Neutral	0.006
BRCA1	P38398-1.2	S789R	Neutral	0.017
BRCA1	P38398-1.2	S789T	Neutral	0.002
BRCA1	P38398-1.2	S789V	Neutral	0.009
BRCA1	P38398-1.2	S789W	Neutral	0.046
BRCA1	P38398-1.2	S789Y	Neutral	0.02
BRCA1	P38398-1.2	T790A	Neutral	0.137
BRCA1	P38398-1.2	T790C	Neutral	0.129
BRCA1	P38398-1.2	T790D	Neutral	0.116
BRCA1	P38398-1.2	T790E	Neutral	0.152
BRCA1	P38398-1.2	T790F	Neutral	0.313
BRCA1	P38398-1.2	T790G	Neutral	0.332
BRCA1	P38398-1.2	T790H	Neutral	0.243
BRCA1	P38398-1.2	T790I	Neutral	0.198
BRCA1	P38398-1.2	T790K	Neutral	0.241
BRCA1	P38398-1.2	T790L	Neutral	0.199
BRCA1	P38398-1.2	T790M	Neutral	0.2
BRCA1	P38398-1.2	T790N	Neutral	0.086
BRCA1	P38398-1.2	T790P	Neutral	0.119
BRCA1	P38398-1.2	T790Q	Neutral	0.168
BRCA1	P38398-1.2	T790R	Neutral	0.298
BRCA1	P38398-1.2	T790S	Neutral	0.087
BRCA1	P38398-1.2	T790V	Neutral	0.102
BRCA1	P38398-1.2	T790W	Neutral	0.456
BRCA1	P38398-1.2	T790Y	Neutral	0.345
BRCA1	P38398-1.2	L791A	Neutral	0.06
BRCA1	P38398-1.2	L791C	Neutral	0.04
BRCA1	P38398-1.2	L791D	Neutral	0.098
BRCA1	P38398-1.2	L791E	Neutral	0.048
BRCA1	P38398-1.2	L791F	Neutral	0.016
BRCA1	P38398-1.2	L791G	Neutral	0.222
BRCA1	P38398-1.2	L791H	Neutral	0.04
BRCA1	P38398-1.2	L791I	Neutral	0.006
BRCA1	P38398-1.2	L791K	Neutral	0.031
BRCA1	P38398-1.2	L791M	Neutral	0.006
BRCA1	P38398-1.2	L791N	Neutral	0.063
BRCA1	P38398-1.2	L791P	Neutral	0.073
BRCA1	P38398-1.2	L791Q	Neutral	0.031
BRCA1	P38398-1.2	L791R	Neutral	0.041
BRCA1	P38398-1.2	L791S	Neutral	0.073
BRCA1	P38398-1.2	L791T	Neutral	0.034
BRCA1	P38398-1.2	L791V	Neutral	0.013
BRCA1	P38398-1.2	L791W	Neutral	0.058
BRCA1	P38398-1.2	L791Y	Neutral	0.026
BRCA1	P38398-1.2	G792A	Neutral	0.077
BRCA1	P38398-1.2	G792C	Neutral	0.273
BRCA1	P38398-1.2	G792D	Neutral	0.169
BRCA1	P38398-1.2	G792E	Neutral	0.305
BRCA1	P38398-1.2	G792F	Pathogenic	0.524
BRCA1	P38398-1.2	G792H	Neutral	0.351
BRCA1	P38398-1.2	G792I	Pathogenic	0.553
BRCA1	P38398-1.2	G792K	Neutral	0.437
BRCA1	P38398-1.2	G792L	Pathogenic	0.554
BRCA1	P38398-1.2	G792M	Neutral	0.465
BRCA1	P38398-1.2	G792N	Neutral	0.137
BRCA1	P38398-1.2	G792P	Neutral	0.223
BRCA1	P38398-1.2	G792Q	Neutral	0.331
BRCA1	P38398-1.2	G792R	Pathogenic	0.509
BRCA1	P38398-1.2	G792S	Neutral	0.088
BRCA1	P38398-1.2	G792T	Neutral	0.236
BRCA1	P38398-1.2	G792V	Neutral	0.364
BRCA1	P38398-1.2	G792W	Pathogenic	0.585
BRCA1	P38398-1.2	G792Y	Pathogenic	0.561
BRCA1	P38398-1.2	K793A	Neutral	0.364
BRCA1	P38398-1.2	K793C	Neutral	0.434
BRCA1	P38398-1.2	K793D	Neutral	0.255
BRCA1	P38398-1.2	K793E	Neutral	0.1
BRCA1	P38398-1.2	K793F	Neutral	0.203
BRCA1	P38398-1.2	K793G	Pathogenic	0.558
BRCA1	P38398-1.2	K793H	Neutral	0.156
BRCA1	P38398-1.2	K793I	Neutral	0.245
BRCA1	P38398-1.2	K793L	Neutral	0.184
BRCA1	P38398-1.2	K793M	Neutral	0.137
BRCA1	P38398-1.2	K793N	Neutral	0.175
BRCA1	P38398-1.2	K793P	Neutral	0.254
BRCA1	P38398-1.2	K793Q	Neutral	0.09
BRCA1	P38398-1.2	K793R	Neutral	0.055
BRCA1	P38398-1.2	K793S	Neutral	0.26
BRCA1	P38398-1.2	K793T	Neutral	0.243
BRCA1	P38398-1.2	K793V	Neutral	0.258
BRCA1	P38398-1.2	K793W	Neutral	0.32
BRCA1	P38398-1.2	K793Y	Neutral	0.17
BRCA1	P38398-1.2	A794C	Neutral	0.294
BRCA1	P38398-1.2	A794D	Neutral	0.489
BRCA1	P38398-1.2	A794E	Neutral	0.498
BRCA1	P38398-1.2	A794F	Pathogenic	0.716
BRCA1	P38398-1.2	A794G	Neutral	0.295
BRCA1	P38398-1.2	A794H	Pathogenic	0.639
BRCA1	P38398-1.2	A794I	Pathogenic	0.578
BRCA1	P38398-1.2	A794K	Pathogenic	0.637
BRCA1	P38398-1.2	A794L	Pathogenic	0.579
BRCA1	P38398-1.2	A794M	Pathogenic	0.581
BRCA1	P38398-1.2	A794N	Pathogenic	0.517
BRCA1	P38398-1.2	A794P	Neutral	0.397
BRCA1	P38398-1.2	A794Q	Pathogenic	0.528
BRCA1	P38398-1.2	A794R	Pathogenic	0.701
BRCA1	P38398-1.2	A794S	Neutral	0.179
BRCA1	P38398-1.2	A794T	Neutral	0.33
BRCA1	P38398-1.2	A794V	Neutral	0.387
BRCA1	P38398-1.2	A794W	Pathogenic	0.87
BRCA1	P38398-1.2	A794Y	Pathogenic	0.745
BRCA1	P38398-1.2	K795A	Pathogenic	0.597
BRCA1	P38398-1.2	K795C	Pathogenic	0.665
BRCA1	P38398-1.2	K795D	Neutral	0.47
BRCA1	P38398-1.2	K795E	Neutral	0.223
BRCA1	P38398-1.2	K795F	Neutral	0.397
BRCA1	P38398-1.2	K795G	Pathogenic	0.766
BRCA1	P38398-1.2	K795H	Neutral	0.324
BRCA1	P38398-1.2	K795I	Neutral	0.456
BRCA1	P38398-1.2	K795L	Neutral	0.369
BRCA1	P38398-1.2	K795M	Neutral	0.291
BRCA1	P38398-1.2	K795N	Neutral	0.355
BRCA1	P38398-1.2	K795P	Neutral	0.468
BRCA1	P38398-1.2	K795Q	Neutral	0.203
BRCA1	P38398-1.2	K795R	Neutral	0.13
BRCA1	P38398-1.2	K795S	Neutral	0.475
BRCA1	P38398-1.2	K795T	Neutral	0.454
BRCA1	P38398-1.2	K795V	Neutral	0.474
BRCA1	P38398-1.2	K795W	Pathogenic	0.548
BRCA1	P38398-1.2	K795Y	Neutral	0.347
BRCA1	P38398-1.2	T796A	Neutral	0.207
BRCA1	P38398-1.2	T796C	Neutral	0.196
BRCA1	P38398-1.2	T796D	Neutral	0.178
BRCA1	P38398-1.2	T796E	Neutral	0.229
BRCA1	P38398-1.2	T796F	Neutral	0.429
BRCA1	P38398-1.2	T796G	Neutral	0.451
BRCA1	P38398-1.2	T796H	Neutral	0.346
BRCA1	P38398-1.2	T796I	Neutral	0.29
BRCA1	P38398-1.2	T796K	Neutral	0.344
BRCA1	P38398-1.2	T796L	Neutral	0.29
BRCA1	P38398-1.2	T796M	Neutral	0.292
BRCA1	P38398-1.2	T796N	Neutral	0.134
BRCA1	P38398-1.2	T796P	Neutral	0.183
BRCA1	P38398-1.2	T796Q	Neutral	0.25
BRCA1	P38398-1.2	T796R	Neutral	0.412
BRCA1	P38398-1.2	T796S	Neutral	0.137
BRCA1	P38398-1.2	T796V	Neutral	0.158
BRCA1	P38398-1.2	T796W	Pathogenic	0.581
BRCA1	P38398-1.2	T796Y	Neutral	0.466
BRCA1	P38398-1.2	E797A	Neutral	0.013
BRCA1	P38398-1.2	E797C	Neutral	0.026
BRCA1	P38398-1.2	E797D	Neutral	0.003
BRCA1	P38398-1.2	E797F	Neutral	0.019
BRCA1	P38398-1.2	E797G	Neutral	0.029
BRCA1	P38398-1.2	E797H	Neutral	0.005
BRCA1	P38398-1.2	E797I	Neutral	0.015
BRCA1	P38398-1.2	E797K	Neutral	0.005
BRCA1	P38398-1.2	E797L	Neutral	0.015
BRCA1	P38398-1.2	E797M	Neutral	0.011
BRCA1	P38398-1.2	E797N	Neutral	0.005
BRCA1	P38398-1.2	E797P	Neutral	0.008
BRCA1	P38398-1.2	E797Q	Neutral	0.002
BRCA1	P38398-1.2	E797R	Neutral	0.009
BRCA1	P38398-1.2	E797S	Neutral	0.008
BRCA1	P38398-1.2	E797T	Neutral	0.008
BRCA1	P38398-1.2	E797V	Neutral	0.008
BRCA1	P38398-1.2	E797W	Neutral	0.034
BRCA1	P38398-1.2	E797Y	Neutral	0.015
BRCA1	P38398-1.2	P798A	Neutral	0.096
BRCA1	P38398-1.2	P798C	Neutral	0.126
BRCA1	P38398-1.2	P798D	Neutral	0.06
BRCA1	P38398-1.2	P798E	Neutral	0.087
BRCA1	P38398-1.2	P798F	Neutral	0.337
BRCA1	P38398-1.2	P798G	Neutral	0.188
BRCA1	P38398-1.2	P798H	Neutral	0.145
BRCA1	P38398-1.2	P798I	Neutral	0.217
BRCA1	P38398-1.2	P798K	Neutral	0.144
BRCA1	P38398-1.2	P798L	Neutral	0.217
BRCA1	P38398-1.2	P798M	Neutral	0.163
BRCA1	P38398-1.2	P798N	Neutral	0.093
BRCA1	P38398-1.2	P798Q	Neutral	0.097
BRCA1	P38398-1.2	P798R	Neutral	0.245
BRCA1	P38398-1.2	P798S	Neutral	0.084
BRCA1	P38398-1.2	P798T	Neutral	0.064
BRCA1	P38398-1.2	P798V	Neutral	0.113
BRCA1	P38398-1.2	P798W	Neutral	0.484
BRCA1	P38398-1.2	P798Y	Neutral	0.291
BRCA1	P38398-1.2	N799A	Neutral	0.221
BRCA1	P38398-1.2	N799C	Neutral	0.209
BRCA1	P38398-1.2	N799D	Neutral	0.054
BRCA1	P38398-1.2	N799E	Neutral	0.089
BRCA1	P38398-1.2	N799F	Neutral	0.331
BRCA1	P38398-1.2	N799G	Neutral	0.174
BRCA1	P38398-1.2	N799H	Neutral	0.076
BRCA1	P38398-1.2	N799I	Neutral	0.279
BRCA1	P38398-1.2	N799K	Neutral	0.147
BRCA1	P38398-1.2	N799L	Neutral	0.28
BRCA1	P38398-1.2	N799M	Neutral	0.214
BRCA1	P38398-1.2	N799P	Neutral	0.144
BRCA1	P38398-1.2	N799Q	Neutral	0.098
BRCA1	P38398-1.2	N799R	Neutral	0.187
BRCA1	P38398-1.2	N799S	Neutral	0.077
BRCA1	P38398-1.2	N799T	Neutral	0.071
BRCA1	P38398-1.2	N799V	Neutral	0.205
BRCA1	P38398-1.2	N799W	Pathogenic	0.568
BRCA1	P38398-1.2	N799Y	Neutral	0.285
BRCA1	P38398-1.2	K800A	Neutral	0.063
BRCA1	P38398-1.2	K800C	Neutral	0.082
BRCA1	P38398-1.2	K800D	Neutral	0.039
BRCA1	P38398-1.2	K800E	Neutral	0.013
BRCA1	P38398-1.2	K800F	Neutral	0.029
BRCA1	P38398-1.2	K800G	Neutral	0.129
BRCA1	P38398-1.2	K800H	Neutral	0.021
BRCA1	P38398-1.2	K800I	Neutral	0.037
BRCA1	P38398-1.2	K800L	Neutral	0.026
BRCA1	P38398-1.2	K800M	Neutral	0.018
BRCA1	P38398-1.2	K800N	Neutral	0.024
BRCA1	P38398-1.2	K800P	Neutral	0.038
BRCA1	P38398-1.2	K800Q	Neutral	0.011
BRCA1	P38398-1.2	K800R	Neutral	0.007
BRCA1	P38398-1.2	K800S	Neutral	0.039
BRCA1	P38398-1.2	K800T	Neutral	0.036
BRCA1	P38398-1.2	K800V	Neutral	0.039
BRCA1	P38398-1.2	K800W	Neutral	0.052
BRCA1	P38398-1.2	K800Y	Neutral	0.023
BRCA1	P38398-1.2	C801A	Neutral	0.029
BRCA1	P38398-1.2	C801D	Neutral	0.06
BRCA1	P38398-1.2	C801E	Neutral	0.12
BRCA1	P38398-1.2	C801F	Neutral	0.107
BRCA1	P38398-1.2	C801G	Neutral	0.118
BRCA1	P38398-1.2	C801H	Neutral	0.105
BRCA1	P38398-1.2	C801I	Neutral	0.061
BRCA1	P38398-1.2	C801K	Neutral	0.144
BRCA1	P38398-1.2	C801L	Neutral	0.061
BRCA1	P38398-1.2	C801M	Neutral	0.062
BRCA1	P38398-1.2	C801N	Neutral	0.067
BRCA1	P38398-1.2	C801P	Neutral	0.06
BRCA1	P38398-1.2	C801Q	Neutral	0.097
BRCA1	P38398-1.2	C801R	Neutral	0.183
BRCA1	P38398-1.2	C801S	Neutral	0.036
BRCA1	P38398-1.2	C801T	Neutral	0.032
BRCA1	P38398-1.2	C801V	Neutral	0.041
BRCA1	P38398-1.2	C801W	Neutral	0.181
BRCA1	P38398-1.2	C801Y	Neutral	0.122
BRCA1	P38398-1.2	V802A	Neutral	0.01
BRCA1	P38398-1.2	V802C	Neutral	0.009
BRCA1	P38398-1.2	V802D	Neutral	0.016
BRCA1	P38398-1.2	V802E	Neutral	0.009
BRCA1	P38398-1.2	V802F	Neutral	0.012
BRCA1	P38398-1.2	V802G	Neutral	0.042
BRCA1	P38398-1.2	V802H	Neutral	0.016
BRCA1	P38398-1.2	V802I	Neutral	0.002
BRCA1	P38398-1.2	V802K	Neutral	0.016
BRCA1	P38398-1.2	V802L	Neutral	0.004
BRCA1	P38398-1.2	V802M	Neutral	0.005
BRCA1	P38398-1.2	V802N	Neutral	0.015
BRCA1	P38398-1.2	V802P	Neutral	0.012
BRCA1	P38398-1.2	V802Q	Neutral	0.01
BRCA1	P38398-1.2	V802R	Neutral	0.031
BRCA1	P38398-1.2	V802S	Neutral	0.017
BRCA1	P38398-1.2	V802T	Neutral	0.005
BRCA1	P38398-1.2	V802W	Neutral	0.043
BRCA1	P38398-1.2	V802Y	Neutral	0.013
BRCA1	P38398-1.2	S803A	Neutral	0.001
BRCA1	P38398-1.2	S803C	Neutral	0.001
BRCA1	P38398-1.2	S803D	Neutral	0.001
BRCA1	P38398-1.2	S803E	Neutral	0.001
BRCA1	P38398-1.2	S803F	Neutral	0.005
BRCA1	P38398-1.2	S803G	Neutral	0.001
BRCA1	P38398-1.2	S803H	Neutral	0.003
BRCA1	P38398-1.2	S803I	Neutral	0.004
BRCA1	P38398-1.2	S803K	Neutral	0.003
BRCA1	P38398-1.2	S803L	Neutral	0.004
BRCA1	P38398-1.2	S803M	Neutral	0.003
BRCA1	P38398-1.2	S803N	Neutral	0.001
BRCA1	P38398-1.2	S803P	Neutral	0.001
BRCA1	P38398-1.2	S803Q	Neutral	0.002
BRCA1	P38398-1.2	S803R	Neutral	0.005
BRCA1	P38398-1.2	S803T	Neutral	0.001
BRCA1	P38398-1.2	S803V	Neutral	0.003
BRCA1	P38398-1.2	S803W	Neutral	0.014
BRCA1	P38398-1.2	S803Y	Neutral	0.006
BRCA1	P38398-1.2	Q804A	Neutral	0.126
BRCA1	P38398-1.2	Q804C	Neutral	0.162
BRCA1	P38398-1.2	Q804D	Neutral	0.056
BRCA1	P38398-1.2	Q804E	Neutral	0.019
BRCA1	P38398-1.2	Q804F	Neutral	0.14
BRCA1	P38398-1.2	Q804G	Neutral	0.242
BRCA1	P38398-1.2	Q804H	Neutral	0.037
BRCA1	P38398-1.2	Q804I	Neutral	0.113
BRCA1	P38398-1.2	Q804K	Neutral	0.037
BRCA1	P38398-1.2	Q804L	Neutral	0.082
BRCA1	P38398-1.2	Q804M	Neutral	0.042
BRCA1	P38398-1.2	Q804N	Neutral	0.05
BRCA1	P38398-1.2	Q804P	Neutral	0.079
BRCA1	P38398-1.2	Q804R	Neutral	0.049
BRCA1	P38398-1.2	Q804S	Neutral	0.081
BRCA1	P38398-1.2	Q804T	Neutral	0.075
BRCA1	P38398-1.2	Q804V	Neutral	0.081
BRCA1	P38398-1.2	Q804W	Neutral	0.173
BRCA1	P38398-1.2	Q804Y	Neutral	0.084
BRCA1	P38398-1.2	C805A	Neutral	0.049
BRCA1	P38398-1.2	C805D	Neutral	0.1
BRCA1	P38398-1.2	C805E	Neutral	0.192
BRCA1	P38398-1.2	C805F	Neutral	0.172
BRCA1	P38398-1.2	C805G	Neutral	0.19
BRCA1	P38398-1.2	C805H	Neutral	0.17
BRCA1	P38398-1.2	C805I	Neutral	0.102
BRCA1	P38398-1.2	C805K	Neutral	0.227
BRCA1	P38398-1.2	C805L	Neutral	0.102
BRCA1	P38398-1.2	C805M	Neutral	0.103
BRCA1	P38398-1.2	C805N	Neutral	0.11
BRCA1	P38398-1.2	C805P	Neutral	0.1
BRCA1	P38398-1.2	C805Q	Neutral	0.157
BRCA1	P38398-1.2	C805R	Neutral	0.281
BRCA1	P38398-1.2	C805S	Neutral	0.061
BRCA1	P38398-1.2	C805T	Neutral	0.054
BRCA1	P38398-1.2	C805V	Neutral	0.07
BRCA1	P38398-1.2	C805W	Neutral	0.278
BRCA1	P38398-1.2	C805Y	Neutral	0.194
BRCA1	P38398-1.2	A806C	Neutral	0.014
BRCA1	P38398-1.2	A806D	Neutral	0.031
BRCA1	P38398-1.2	A806E	Neutral	0.032
BRCA1	P38398-1.2	A806F	Neutral	0.078
BRCA1	P38398-1.2	A806G	Neutral	0.014
BRCA1	P38398-1.2	A806H	Neutral	0.056
BRCA1	P38398-1.2	A806I	Neutral	0.044
BRCA1	P38398-1.2	A806K	Neutral	0.056
BRCA1	P38398-1.2	A806L	Neutral	0.044
BRCA1	P38398-1.2	A806M	Neutral	0.045
BRCA1	P38398-1.2	A806N	Neutral	0.035
BRCA1	P38398-1.2	A806P	Neutral	0.022
BRCA1	P38398-1.2	A806Q	Neutral	0.036
BRCA1	P38398-1.2	A806R	Neutral	0.073
BRCA1	P38398-1.2	A806S	Neutral	0.007
BRCA1	P38398-1.2	A806T	Neutral	0.016
BRCA1	P38398-1.2	A806V	Neutral	0.021
BRCA1	P38398-1.2	A806W	Neutral	0.184
BRCA1	P38398-1.2	A806Y	Neutral	0.09
BRCA1	P38398-1.2	A807C	Neutral	0.497
BRCA1	P38398-1.2	A807D	Pathogenic	0.694
BRCA1	P38398-1.2	A807E	Pathogenic	0.702
BRCA1	P38398-1.2	A807F	Pathogenic	0.857
BRCA1	P38398-1.2	A807G	Neutral	0.498
BRCA1	P38398-1.2	A807H	Pathogenic	0.808
BRCA1	P38398-1.2	A807I	Pathogenic	0.765
BRCA1	P38398-1.2	A807K	Pathogenic	0.806
BRCA1	P38398-1.2	A807L	Pathogenic	0.765
BRCA1	P38398-1.2	A807M	Pathogenic	0.767
BRCA1	P38398-1.2	A807N	Pathogenic	0.718
BRCA1	P38398-1.2	A807P	Pathogenic	0.609
BRCA1	P38398-1.2	A807Q	Pathogenic	0.726
BRCA1	P38398-1.2	A807R	Pathogenic	0.848
BRCA1	P38398-1.2	A807S	Neutral	0.341
BRCA1	P38398-1.2	A807T	Pathogenic	0.538
BRCA1	P38398-1.2	A807V	Pathogenic	0.6
BRCA1	P38398-1.2	A807W	Pathogenic	0.941
BRCA1	P38398-1.2	A807Y	Pathogenic	0.874
BRCA1	P38398-1.2	F808A	Neutral	0.021
BRCA1	P38398-1.2	F808C	Neutral	0.014
BRCA1	P38398-1.2	F808D	Neutral	0.017
BRCA1	P38398-1.2	F808E	Neutral	0.012
BRCA1	P38398-1.2	F808G	Neutral	0.045
BRCA1	P38398-1.2	F808H	Neutral	0.005
BRCA1	P38398-1.2	F808I	Neutral	0.003
BRCA1	P38398-1.2	F808K	Neutral	0.007
BRCA1	P38398-1.2	F808L	Neutral	0.003
BRCA1	P38398-1.2	F808M	Neutral	0.003
BRCA1	P38398-1.2	F808N	Neutral	0.016
BRCA1	P38398-1.2	F808P	Neutral	0.026
BRCA1	P38398-1.2	F808Q	Neutral	0.011
BRCA1	P38398-1.2	F808R	Neutral	0.009
BRCA1	P38398-1.2	F808S	Neutral	0.018
BRCA1	P38398-1.2	F808T	Neutral	0.012
BRCA1	P38398-1.2	F808V	Neutral	0.006
BRCA1	P38398-1.2	F808W	Neutral	0.003
BRCA1	P38398-1.2	F808Y	Neutral	0.001
BRCA1	P38398-1.2	E809A	Neutral	0.067
BRCA1	P38398-1.2	E809C	Neutral	0.122
BRCA1	P38398-1.2	E809D	Neutral	0.014
BRCA1	P38398-1.2	E809F	Neutral	0.093
BRCA1	P38398-1.2	E809G	Neutral	0.138
BRCA1	P38398-1.2	E809H	Neutral	0.024
BRCA1	P38398-1.2	E809I	Neutral	0.074
BRCA1	P38398-1.2	E809K	Neutral	0.024
BRCA1	P38398-1.2	E809L	Neutral	0.074
BRCA1	P38398-1.2	E809M	Neutral	0.053
BRCA1	P38398-1.2	E809N	Neutral	0.026
BRCA1	P38398-1.2	E809P	Neutral	0.041
BRCA1	P38398-1.2	E809Q	Neutral	0.011
BRCA1	P38398-1.2	E809R	Neutral	0.045
BRCA1	P38398-1.2	E809S	Neutral	0.042
BRCA1	P38398-1.2	E809T	Neutral	0.039
BRCA1	P38398-1.2	E809V	Neutral	0.042
BRCA1	P38398-1.2	E809W	Neutral	0.158
BRCA1	P38398-1.2	E809Y	Neutral	0.076
BRCA1	P38398-1.2	N810A	Neutral	0.263
BRCA1	P38398-1.2	N810C	Neutral	0.25
BRCA1	P38398-1.2	N810D	Neutral	0.067
BRCA1	P38398-1.2	N810E	Neutral	0.109
BRCA1	P38398-1.2	N810F	Neutral	0.384
BRCA1	P38398-1.2	N810G	Neutral	0.209
BRCA1	P38398-1.2	N810H	Neutral	0.093
BRCA1	P38398-1.2	N810I	Neutral	0.328
BRCA1	P38398-1.2	N810K	Neutral	0.179
BRCA1	P38398-1.2	N810L	Neutral	0.329
BRCA1	P38398-1.2	N810M	Neutral	0.256
BRCA1	P38398-1.2	N810P	Neutral	0.175
BRCA1	P38398-1.2	N810Q	Neutral	0.12
BRCA1	P38398-1.2	N810R	Neutral	0.225
BRCA1	P38398-1.2	N810S	Neutral	0.096
BRCA1	P38398-1.2	N810T	Neutral	0.088
BRCA1	P38398-1.2	N810V	Neutral	0.245
BRCA1	P38398-1.2	N810W	Pathogenic	0.624
BRCA1	P38398-1.2	N810Y	Neutral	0.335
BRCA1	P38398-1.2	P811A	Pathogenic	0.9
BRCA1	P38398-1.2	P811C	Pathogenic	0.924
BRCA1	P38398-1.2	P811D	Pathogenic	0.843
BRCA1	P38398-1.2	P811E	Pathogenic	0.89
BRCA1	P38398-1.2	P811F	Pathogenic	0.977
BRCA1	P38398-1.2	P811G	Pathogenic	0.951
BRCA1	P38398-1.2	P811H	Pathogenic	0.935
BRCA1	P38398-1.2	P811I	Pathogenic	0.959
BRCA1	P38398-1.2	P811K	Pathogenic	0.934
BRCA1	P38398-1.2	P811L	Pathogenic	0.959
BRCA1	P38398-1.2	P811M	Pathogenic	0.943
BRCA1	P38398-1.2	P811N	Pathogenic	0.897
BRCA1	P38398-1.2	P811Q	Pathogenic	0.901
BRCA1	P38398-1.2	P811R	Pathogenic	0.965
BRCA1	P38398-1.2	P811S	Pathogenic	0.886
BRCA1	P38398-1.2	P811T	Pathogenic	0.852
BRCA1	P38398-1.2	P811V	Pathogenic	0.915
BRCA1	P38398-1.2	P811W	Pathogenic	0.988
BRCA1	P38398-1.2	P811Y	Pathogenic	0.972
BRCA1	P38398-1.2	K812A	Pathogenic	0.537
BRCA1	P38398-1.2	K812C	Pathogenic	0.609
BRCA1	P38398-1.2	K812D	Neutral	0.41
BRCA1	P38398-1.2	K812E	Neutral	0.183
BRCA1	P38398-1.2	K812F	Neutral	0.34
BRCA1	P38398-1.2	K812G	Pathogenic	0.719
BRCA1	P38398-1.2	K812H	Neutral	0.273
BRCA1	P38398-1.2	K812I	Neutral	0.397
BRCA1	P38398-1.2	K812L	Neutral	0.314
BRCA1	P38398-1.2	K812M	Neutral	0.243
BRCA1	P38398-1.2	K812N	Neutral	0.301
BRCA1	P38398-1.2	K812P	Neutral	0.409
BRCA1	P38398-1.2	K812Q	Neutral	0.166
BRCA1	P38398-1.2	K812R	Neutral	0.105
BRCA1	P38398-1.2	K812S	Neutral	0.416
BRCA1	P38398-1.2	K812T	Neutral	0.395
BRCA1	P38398-1.2	K812V	Neutral	0.414
BRCA1	P38398-1.2	K812W	Neutral	0.488
BRCA1	P38398-1.2	K812Y	Neutral	0.294
BRCA1	P38398-1.2	G813A	Neutral	0.309
BRCA1	P38398-1.2	G813C	Pathogenic	0.668
BRCA1	P38398-1.2	G813D	Pathogenic	0.521
BRCA1	P38398-1.2	G813E	Pathogenic	0.701
BRCA1	P38398-1.2	G813F	Pathogenic	0.854
BRCA1	P38398-1.2	G813H	Pathogenic	0.743
BRCA1	P38398-1.2	G813I	Pathogenic	0.869
BRCA1	P38398-1.2	G813K	Pathogenic	0.806
BRCA1	P38398-1.2	G813L	Pathogenic	0.869
BRCA1	P38398-1.2	G813M	Pathogenic	0.823
BRCA1	P38398-1.2	G813N	Neutral	0.459
BRCA1	P38398-1.2	G813P	Pathogenic	0.605
BRCA1	P38398-1.2	G813Q	Pathogenic	0.725
BRCA1	P38398-1.2	G813R	Pathogenic	0.847
BRCA1	P38398-1.2	G813S	Neutral	0.339
BRCA1	P38398-1.2	G813T	Pathogenic	0.623
BRCA1	P38398-1.2	G813V	Pathogenic	0.753
BRCA1	P38398-1.2	G813W	Pathogenic	0.883
BRCA1	P38398-1.2	G813Y	Pathogenic	0.872
BRCA1	P38398-1.2	L814A	Pathogenic	0.584
BRCA1	P38398-1.2	L814C	Neutral	0.483
BRCA1	P38398-1.2	L814D	Pathogenic	0.707
BRCA1	P38398-1.2	L814E	Pathogenic	0.529
BRCA1	P38398-1.2	L814F	Neutral	0.265
BRCA1	P38398-1.2	L814G	Pathogenic	0.864
BRCA1	P38398-1.2	L814H	Neutral	0.483
BRCA1	P38398-1.2	L814I	Neutral	0.12
BRCA1	P38398-1.2	L814K	Neutral	0.415
BRCA1	P38398-1.2	L814M	Neutral	0.119
BRCA1	P38398-1.2	L814N	Pathogenic	0.6
BRCA1	P38398-1.2	L814P	Pathogenic	0.638
BRCA1	P38398-1.2	L814Q	Neutral	0.413
BRCA1	P38398-1.2	L814R	Neutral	0.486
BRCA1	P38398-1.2	L814S	Pathogenic	0.637
BRCA1	P38398-1.2	L814T	Neutral	0.441
BRCA1	P38398-1.2	L814V	Neutral	0.229
BRCA1	P38398-1.2	L814W	Pathogenic	0.579
BRCA1	P38398-1.2	L814Y	Neutral	0.369
BRCA1	P38398-1.2	I815A	Neutral	0.039
BRCA1	P38398-1.2	I815C	Neutral	0.026
BRCA1	P38398-1.2	I815D	Neutral	0.046
BRCA1	P38398-1.2	I815E	Neutral	0.032
BRCA1	P38398-1.2	I815F	Neutral	0.01
BRCA1	P38398-1.2	I815G	Neutral	0.156
BRCA1	P38398-1.2	I815H	Neutral	0.027
BRCA1	P38398-1.2	I815K	Neutral	0.029
BRCA1	P38398-1.2	I815L	Neutral	0.004
BRCA1	P38398-1.2	I815M	Neutral	0.006
BRCA1	P38398-1.2	I815N	Neutral	0.042
BRCA1	P38398-1.2	I815P	Neutral	0.049
BRCA1	P38398-1.2	I815Q	Neutral	0.029
BRCA1	P38398-1.2	I815R	Neutral	0.038
BRCA1	P38398-1.2	I815S	Neutral	0.049
BRCA1	P38398-1.2	I815T	Neutral	0.022
BRCA1	P38398-1.2	I815V	Neutral	0.004
BRCA1	P38398-1.2	I815W	Neutral	0.055
BRCA1	P38398-1.2	I815Y	Neutral	0.017
BRCA1	P38398-1.2	H816A	Neutral	0.103
BRCA1	P38398-1.2	H816C	Neutral	0.096
BRCA1	P38398-1.2	H816D	Neutral	0.044
BRCA1	P38398-1.2	H816E	Neutral	0.021
BRCA1	P38398-1.2	H816F	Neutral	0.035
BRCA1	P38398-1.2	H816G	Neutral	0.148
BRCA1	P38398-1.2	H816I	Neutral	0.056
BRCA1	P38398-1.2	H816K	Neutral	0.035
BRCA1	P38398-1.2	H816L	Neutral	0.056
BRCA1	P38398-1.2	H816M	Neutral	0.04
BRCA1	P38398-1.2	H816N	Neutral	0.02
BRCA1	P38398-1.2	H816P	Neutral	0.064
BRCA1	P38398-1.2	H816Q	Neutral	0.019
BRCA1	P38398-1.2	H816R	Neutral	0.033
BRCA1	P38398-1.2	H816S	Neutral	0.065
BRCA1	P38398-1.2	H816T	Neutral	0.06
BRCA1	P38398-1.2	H816V	Neutral	0.065
BRCA1	P38398-1.2	H816W	Neutral	0.088
BRCA1	P38398-1.2	H816Y	Neutral	0.014
BRCA1	P38398-1.2	G817A	Neutral	0.027
BRCA1	P38398-1.2	G817C	Neutral	0.112
BRCA1	P38398-1.2	G817D	Neutral	0.064
BRCA1	P38398-1.2	G817E	Neutral	0.128
BRCA1	P38398-1.2	G817F	Neutral	0.269
BRCA1	P38398-1.2	G817H	Neutral	0.154
BRCA1	P38398-1.2	G817I	Neutral	0.294
BRCA1	P38398-1.2	G817K	Neutral	0.207
BRCA1	P38398-1.2	G817L	Neutral	0.294
BRCA1	P38398-1.2	G817M	Neutral	0.226
BRCA1	P38398-1.2	G817N	Neutral	0.051
BRCA1	P38398-1.2	G817P	Neutral	0.088
BRCA1	P38398-1.2	G817Q	Neutral	0.142
BRCA1	P38398-1.2	G817R	Neutral	0.258
BRCA1	P38398-1.2	G817S	Neutral	0.031
BRCA1	P38398-1.2	G817T	Neutral	0.094
BRCA1	P38398-1.2	G817V	Neutral	0.161
BRCA1	P38398-1.2	G817W	Neutral	0.321
BRCA1	P38398-1.2	G817Y	Neutral	0.3
BRCA1	P38398-1.2	C818A	Neutral	0.036
BRCA1	P38398-1.2	C818D	Neutral	0.074
BRCA1	P38398-1.2	C818E	Neutral	0.146
BRCA1	P38398-1.2	C818F	Neutral	0.13
BRCA1	P38398-1.2	C818G	Neutral	0.144
BRCA1	P38398-1.2	C818H	Neutral	0.128
BRCA1	P38398-1.2	C818I	Neutral	0.075
BRCA1	P38398-1.2	C818K	Neutral	0.174
BRCA1	P38398-1.2	C818L	Neutral	0.075
BRCA1	P38398-1.2	C818M	Neutral	0.076
BRCA1	P38398-1.2	C818N	Neutral	0.082
BRCA1	P38398-1.2	C818P	Neutral	0.074
BRCA1	P38398-1.2	C818Q	Neutral	0.118
BRCA1	P38398-1.2	C818R	Neutral	0.219
BRCA1	P38398-1.2	C818S	Neutral	0.044
BRCA1	P38398-1.2	C818T	Neutral	0.039
BRCA1	P38398-1.2	C818V	Neutral	0.051
BRCA1	P38398-1.2	C818W	Neutral	0.216
BRCA1	P38398-1.2	C818Y	Neutral	0.148
BRCA1	P38398-1.2	S819A	Neutral	0.058
BRCA1	P38398-1.2	S819C	Neutral	0.129
BRCA1	P38398-1.2	S819D	Neutral	0.103
BRCA1	P38398-1.2	S819E	Neutral	0.147
BRCA1	P38398-1.2	S819F	Neutral	0.383
BRCA1	P38398-1.2	S819G	Neutral	0.12
BRCA1	P38398-1.2	S819H	Neutral	0.234
BRCA1	P38398-1.2	S819I	Neutral	0.327
BRCA1	P38398-1.2	S819K	Neutral	0.234
BRCA1	P38398-1.2	S819L	Neutral	0.328
BRCA1	P38398-1.2	S819M	Neutral	0.255
BRCA1	P38398-1.2	S819N	Neutral	0.082
BRCA1	P38398-1.2	S819P	Neutral	0.14
BRCA1	P38398-1.2	S819Q	Neutral	0.163
BRCA1	P38398-1.2	S819R	Neutral	0.369
BRCA1	P38398-1.2	S819T	Neutral	0.078
BRCA1	P38398-1.2	S819V	Neutral	0.244
BRCA1	P38398-1.2	S819W	Pathogenic	0.623
BRCA1	P38398-1.2	S819Y	Neutral	0.419
BRCA1	P38398-1.2	K820A	Neutral	0.493
BRCA1	P38398-1.2	K820C	Pathogenic	0.566
BRCA1	P38398-1.2	K820D	Neutral	0.368
BRCA1	P38398-1.2	K820E	Neutral	0.158
BRCA1	P38398-1.2	K820F	Neutral	0.302
BRCA1	P38398-1.2	K820G	Pathogenic	0.682
BRCA1	P38398-1.2	K820H	Neutral	0.239
BRCA1	P38398-1.2	K820I	Neutral	0.355
BRCA1	P38398-1.2	K820L	Neutral	0.277
BRCA1	P38398-1.2	K820M	Neutral	0.212
BRCA1	P38398-1.2	K820N	Neutral	0.265
BRCA1	P38398-1.2	K820P	Neutral	0.366
BRCA1	P38398-1.2	K820Q	Neutral	0.143
BRCA1	P38398-1.2	K820R	Neutral	0.09
BRCA1	P38398-1.2	K820S	Neutral	0.373
BRCA1	P38398-1.2	K820T	Neutral	0.353
BRCA1	P38398-1.2	K820V	Neutral	0.371
BRCA1	P38398-1.2	K820W	Neutral	0.444
BRCA1	P38398-1.2	K820Y	Neutral	0.258
BRCA1	P38398-1.2	D821A	Neutral	0.487
BRCA1	P38398-1.2	D821C	Neutral	0.47
BRCA1	P38398-1.2	D821E	Neutral	0.165
BRCA1	P38398-1.2	D821F	Pathogenic	0.675
BRCA1	P38398-1.2	D821G	Pathogenic	0.503
BRCA1	P38398-1.2	D821H	Neutral	0.415
BRCA1	P38398-1.2	D821I	Pathogenic	0.619
BRCA1	P38398-1.2	D821K	Pathogenic	0.511
BRCA1	P38398-1.2	D821L	Pathogenic	0.701
BRCA1	P38398-1.2	D821M	Pathogenic	0.621
BRCA1	P38398-1.2	D821N	Neutral	0.175
BRCA1	P38398-1.2	D821P	Neutral	0.282
BRCA1	P38398-1.2	D821Q	Neutral	0.312
BRCA1	P38398-1.2	D821R	Pathogenic	0.668
BRCA1	P38398-1.2	D821S	Neutral	0.288
BRCA1	P38398-1.2	D821T	Neutral	0.288
BRCA1	P38398-1.2	D821V	Pathogenic	0.518
BRCA1	P38398-1.2	D821W	Pathogenic	0.846
BRCA1	P38398-1.2	D821Y	Pathogenic	0.706
BRCA1	P38398-1.2	N822A	Neutral	0.024
BRCA1	P38398-1.2	N822C	Neutral	0.022
BRCA1	P38398-1.2	N822D	Neutral	0.005
BRCA1	P38398-1.2	N822E	Neutral	0.008
BRCA1	P38398-1.2	N822F	Neutral	0.041
BRCA1	P38398-1.2	N822G	Neutral	0.018
BRCA1	P38398-1.2	N822H	Neutral	0.007
BRCA1	P38398-1.2	N822I	Neutral	0.032
BRCA1	P38398-1.2	N822K	Neutral	0.015
BRCA1	P38398-1.2	N822L	Neutral	0.032
BRCA1	P38398-1.2	N822M	Neutral	0.023
BRCA1	P38398-1.2	N822P	Neutral	0.014
BRCA1	P38398-1.2	N822Q	Neutral	0.009
BRCA1	P38398-1.2	N822R	Neutral	0.019
BRCA1	P38398-1.2	N822S	Neutral	0.007
BRCA1	P38398-1.2	N822T	Neutral	0.007
BRCA1	P38398-1.2	N822V	Neutral	0.022
BRCA1	P38398-1.2	N822W	Neutral	0.102
BRCA1	P38398-1.2	N822Y	Neutral	0.033
BRCA1	P38398-1.2	R823A	Pathogenic	0.636
BRCA1	P38398-1.2	R823C	Pathogenic	0.701
BRCA1	P38398-1.2	R823D	Pathogenic	0.601
BRCA1	P38398-1.2	R823E	Neutral	0.328
BRCA1	P38398-1.2	R823F	Neutral	0.438
BRCA1	P38398-1.2	R823G	Pathogenic	0.794
BRCA1	P38398-1.2	R823H	Neutral	0.282
BRCA1	P38398-1.2	R823I	Neutral	0.498
BRCA1	P38398-1.2	R823K	Neutral	0.117
BRCA1	P38398-1.2	R823L	Neutral	0.409
BRCA1	P38398-1.2	R823M	Neutral	0.326
BRCA1	P38398-1.2	R823N	Neutral	0.394
BRCA1	P38398-1.2	R823P	Pathogenic	0.6
BRCA1	P38398-1.2	R823Q	Neutral	0.231
BRCA1	P38398-1.2	R823S	Pathogenic	0.607
BRCA1	P38398-1.2	R823T	Neutral	0.496
BRCA1	P38398-1.2	R823V	Pathogenic	0.605
BRCA1	P38398-1.2	R823W	Neutral	0.446
BRCA1	P38398-1.2	R823Y	Neutral	0.325
BRCA1	P38398-1.2	N824A	Neutral	0.405
BRCA1	P38398-1.2	N824C	Neutral	0.388
BRCA1	P38398-1.2	N824D	Neutral	0.12
BRCA1	P38398-1.2	N824E	Neutral	0.19
BRCA1	P38398-1.2	N824F	Pathogenic	0.543
BRCA1	P38398-1.2	N824G	Neutral	0.336
BRCA1	P38398-1.2	N824H	Neutral	0.164
BRCA1	P38398-1.2	N824I	Neutral	0.482
BRCA1	P38398-1.2	N824K	Neutral	0.293
BRCA1	P38398-1.2	N824L	Neutral	0.483
BRCA1	P38398-1.2	N824M	Neutral	0.396
BRCA1	P38398-1.2	N824P	Neutral	0.289
BRCA1	P38398-1.2	N824Q	Neutral	0.207
BRCA1	P38398-1.2	N824R	Neutral	0.356
BRCA1	P38398-1.2	N824S	Neutral	0.168
BRCA1	P38398-1.2	N824T	Neutral	0.156
BRCA1	P38398-1.2	N824V	Neutral	0.382
BRCA1	P38398-1.2	N824W	Pathogenic	0.76
BRCA1	P38398-1.2	N824Y	Neutral	0.49
BRCA1	P38398-1.2	D825A	Neutral	0.073
BRCA1	P38398-1.2	D825C	Neutral	0.069
BRCA1	P38398-1.2	D825E	Neutral	0.016
BRCA1	P38398-1.2	D825F	Neutral	0.147
BRCA1	P38398-1.2	D825G	Neutral	0.078
BRCA1	P38398-1.2	D825H	Neutral	0.056
BRCA1	P38398-1.2	D825I	Neutral	0.119
BRCA1	P38398-1.2	D825K	Neutral	0.08
BRCA1	P38398-1.2	D825L	Neutral	0.163
BRCA1	P38398-1.2	D825M	Neutral	0.12
BRCA1	P38398-1.2	D825N	Neutral	0.017
BRCA1	P38398-1.2	D825P	Neutral	0.032
BRCA1	P38398-1.2	D825Q	Neutral	0.036
BRCA1	P38398-1.2	D825R	Neutral	0.144
BRCA1	P38398-1.2	D825S	Neutral	0.033
BRCA1	P38398-1.2	D825T	Neutral	0.033
BRCA1	P38398-1.2	D825V	Neutral	0.082
BRCA1	P38398-1.2	D825W	Neutral	0.315
BRCA1	P38398-1.2	D825Y	Neutral	0.167
BRCA1	P38398-1.2	T826A	Neutral	0.137
BRCA1	P38398-1.2	T826C	Neutral	0.128
BRCA1	P38398-1.2	T826D	Neutral	0.116
BRCA1	P38398-1.2	T826E	Neutral	0.152
BRCA1	P38398-1.2	T826F	Neutral	0.312
BRCA1	P38398-1.2	T826G	Neutral	0.332
BRCA1	P38398-1.2	T826H	Neutral	0.242
BRCA1	P38398-1.2	T826I	Neutral	0.198
BRCA1	P38398-1.2	T826K	Neutral	0.241
BRCA1	P38398-1.2	T826L	Neutral	0.198
BRCA1	P38398-1.2	T826M	Neutral	0.2
BRCA1	P38398-1.2	T826N	Neutral	0.085
BRCA1	P38398-1.2	T826P	Neutral	0.119
BRCA1	P38398-1.2	T826Q	Neutral	0.168
BRCA1	P38398-1.2	T826R	Neutral	0.297
BRCA1	P38398-1.2	T826S	Neutral	0.087
BRCA1	P38398-1.2	T826V	Neutral	0.102
BRCA1	P38398-1.2	T826W	Neutral	0.456
BRCA1	P38398-1.2	T826Y	Neutral	0.345
BRCA1	P38398-1.2	E827A	Pathogenic	0.788
BRCA1	P38398-1.2	E827C	Pathogenic	0.877
BRCA1	P38398-1.2	E827D	Neutral	0.426
BRCA1	P38398-1.2	E827F	Pathogenic	0.84
BRCA1	P38398-1.2	E827G	Pathogenic	0.891
BRCA1	P38398-1.2	E827H	Pathogenic	0.554
BRCA1	P38398-1.2	E827I	Pathogenic	0.804
BRCA1	P38398-1.2	E827K	Pathogenic	0.56
BRCA1	P38398-1.2	E827L	Pathogenic	0.804
BRCA1	P38398-1.2	E827M	Pathogenic	0.742
BRCA1	P38398-1.2	E827N	Pathogenic	0.579
BRCA1	P38398-1.2	E827P	Pathogenic	0.688
BRCA1	P38398-1.2	E827Q	Neutral	0.356
BRCA1	P38398-1.2	E827R	Pathogenic	0.709
BRCA1	P38398-1.2	E827S	Pathogenic	0.694
BRCA1	P38398-1.2	E827T	Pathogenic	0.676
BRCA1	P38398-1.2	E827V	Pathogenic	0.693
BRCA1	P38398-1.2	E827W	Pathogenic	0.906
BRCA1	P38398-1.2	E827Y	Pathogenic	0.809
BRCA1	P38398-1.2	G828A	Neutral	0.284
BRCA1	P38398-1.2	G828C	Pathogenic	0.641
BRCA1	P38398-1.2	G828D	Neutral	0.491
BRCA1	P38398-1.2	G828E	Pathogenic	0.675
BRCA1	P38398-1.2	G828F	Pathogenic	0.839
BRCA1	P38398-1.2	G828H	Pathogenic	0.719
BRCA1	P38398-1.2	G828I	Pathogenic	0.855
BRCA1	P38398-1.2	G828K	Pathogenic	0.786
BRCA1	P38398-1.2	G828L	Pathogenic	0.855
BRCA1	P38398-1.2	G828M	Pathogenic	0.805
BRCA1	P38398-1.2	G828N	Neutral	0.429
BRCA1	P38398-1.2	G828P	Pathogenic	0.576
BRCA1	P38398-1.2	G828Q	Pathogenic	0.701
BRCA1	P38398-1.2	G828R	Pathogenic	0.831
BRCA1	P38398-1.2	G828S	Neutral	0.313
BRCA1	P38398-1.2	G828T	Pathogenic	0.595
BRCA1	P38398-1.2	G828V	Pathogenic	0.73
BRCA1	P38398-1.2	G828W	Pathogenic	0.87
BRCA1	P38398-1.2	G828Y	Pathogenic	0.858
BRCA1	P38398-1.2	F829A	Pathogenic	0.713
BRCA1	P38398-1.2	F829C	Pathogenic	0.623
BRCA1	P38398-1.2	F829D	Pathogenic	0.673
BRCA1	P38398-1.2	F829E	Pathogenic	0.58
BRCA1	P38398-1.2	F829G	Pathogenic	0.844
BRCA1	P38398-1.2	F829H	Neutral	0.357
BRCA1	P38398-1.2	F829I	Neutral	0.258
BRCA1	P38398-1.2	F829K	Neutral	0.435
BRCA1	P38398-1.2	F829L	Neutral	0.258
BRCA1	P38398-1.2	F829M	Neutral	0.256
BRCA1	P38398-1.2	F829N	Pathogenic	0.649
BRCA1	P38398-1.2	F829P	Pathogenic	0.757
BRCA1	P38398-1.2	F829Q	Pathogenic	0.555
BRCA1	P38398-1.2	F829R	Pathogenic	0.507
BRCA1	P38398-1.2	F829S	Pathogenic	0.684
BRCA1	P38398-1.2	F829T	Pathogenic	0.582
BRCA1	P38398-1.2	F829V	Neutral	0.43
BRCA1	P38398-1.2	F829W	Neutral	0.259
BRCA1	P38398-1.2	F829Y	Neutral	0.093
BRCA1	P38398-1.2	K830A	Neutral	0.109
BRCA1	P38398-1.2	K830C	Neutral	0.141
BRCA1	P38398-1.2	K830D	Neutral	0.069
BRCA1	P38398-1.2	K830E	Neutral	0.023
BRCA1	P38398-1.2	K830F	Neutral	0.052
BRCA1	P38398-1.2	K830G	Neutral	0.213
BRCA1	P38398-1.2	K830H	Neutral	0.038
BRCA1	P38398-1.2	K830I	Neutral	0.065
BRCA1	P38398-1.2	K830L	Neutral	0.046
BRCA1	P38398-1.2	K830M	Neutral	0.033
BRCA1	P38398-1.2	K830N	Neutral	0.044
BRCA1	P38398-1.2	K830P	Neutral	0.068
BRCA1	P38398-1.2	K830Q	Neutral	0.021
BRCA1	P38398-1.2	K830R	Neutral	0.012
BRCA1	P38398-1.2	K830S	Neutral	0.07
BRCA1	P38398-1.2	K830T	Neutral	0.065
BRCA1	P38398-1.2	K830V	Neutral	0.07
BRCA1	P38398-1.2	K830W	Neutral	0.092
BRCA1	P38398-1.2	K830Y	Neutral	0.042
BRCA1	P38398-1.2	Y831A	Neutral	0.165
BRCA1	P38398-1.2	Y831C	Neutral	0.116
BRCA1	P38398-1.2	Y831D	Neutral	0.14
BRCA1	P38398-1.2	Y831E	Neutral	0.071
BRCA1	P38398-1.2	Y831F	Neutral	0.007
BRCA1	P38398-1.2	Y831G	Neutral	0.301
BRCA1	P38398-1.2	Y831H	Neutral	0.015
BRCA1	P38398-1.2	Y831I	Neutral	0.037
BRCA1	P38398-1.2	Y831K	Neutral	0.041
BRCA1	P38398-1.2	Y831L	Neutral	0.037
BRCA1	P38398-1.2	Y831M	Neutral	0.037
BRCA1	P38398-1.2	Y831N	Neutral	0.092
BRCA1	P38398-1.2	Y831P	Neutral	0.147
BRCA1	P38398-1.2	Y831Q	Neutral	0.046
BRCA1	P38398-1.2	Y831R	Neutral	0.042
BRCA1	P38398-1.2	Y831S	Neutral	0.146
BRCA1	P38398-1.2	Y831T	Neutral	0.1
BRCA1	P38398-1.2	Y831V	Neutral	0.056
BRCA1	P38398-1.2	Y831W	Neutral	0.014
BRCA1	P38398-1.2	P832A	Neutral	0.375
BRCA1	P38398-1.2	P832C	Neutral	0.45
BRCA1	P38398-1.2	P832D	Neutral	0.265
BRCA1	P38398-1.2	P832E	Neutral	0.35
BRCA1	P38398-1.2	P832F	Pathogenic	0.742
BRCA1	P38398-1.2	P832G	Pathogenic	0.567
BRCA1	P38398-1.2	P832H	Neutral	0.49
BRCA1	P38398-1.2	P832I	Pathogenic	0.61
BRCA1	P38398-1.2	P832K	Neutral	0.488
BRCA1	P38398-1.2	P832L	Pathogenic	0.611
BRCA1	P38398-1.2	P832M	Pathogenic	0.524
BRCA1	P38398-1.2	P832N	Neutral	0.368
BRCA1	P38398-1.2	P832Q	Neutral	0.378
BRCA1	P38398-1.2	P832R	Pathogenic	0.647
BRCA1	P38398-1.2	P832S	Neutral	0.343
BRCA1	P38398-1.2	P832T	Neutral	0.278
BRCA1	P38398-1.2	P832V	Neutral	0.419
BRCA1	P38398-1.2	P832W	Pathogenic	0.842
BRCA1	P38398-1.2	P832Y	Pathogenic	0.699
BRCA1	P38398-1.2	L833A	Pathogenic	0.962
BRCA1	P38398-1.2	L833C	Pathogenic	0.944
BRCA1	P38398-1.2	L833D	Pathogenic	0.977
BRCA1	P38398-1.2	L833E	Pathogenic	0.953
BRCA1	P38398-1.2	L833F	Pathogenic	0.867
BRCA1	P38398-1.2	L833G	Pathogenic	0.991
BRCA1	P38398-1.2	L833H	Pathogenic	0.944
BRCA1	P38398-1.2	L833I	Pathogenic	0.711
BRCA1	P38398-1.2	L833K	Pathogenic	0.928
BRCA1	P38398-1.2	L833M	Pathogenic	0.709
BRCA1	P38398-1.2	L833N	Pathogenic	0.964
BRCA1	P38398-1.2	L833P	Pathogenic	0.969
BRCA1	P38398-1.2	L833Q	Pathogenic	0.927
BRCA1	P38398-1.2	L833R	Pathogenic	0.945
BRCA1	P38398-1.2	L833S	Pathogenic	0.969
BRCA1	P38398-1.2	L833T	Pathogenic	0.934
BRCA1	P38398-1.2	L833V	Pathogenic	0.843
BRCA1	P38398-1.2	L833W	Pathogenic	0.961
BRCA1	P38398-1.2	L833Y	Pathogenic	0.913
BRCA1	P38398-1.2	G834A	Neutral	0.032
BRCA1	P38398-1.2	G834C	Neutral	0.128
BRCA1	P38398-1.2	G834D	Neutral	0.074
BRCA1	P38398-1.2	G834E	Neutral	0.146
BRCA1	P38398-1.2	G834F	Neutral	0.301
BRCA1	P38398-1.2	G834H	Neutral	0.175
BRCA1	P38398-1.2	G834I	Neutral	0.326
BRCA1	P38398-1.2	G834K	Neutral	0.233
BRCA1	P38398-1.2	G834L	Neutral	0.327
BRCA1	P38398-1.2	G834M	Neutral	0.254
BRCA1	P38398-1.2	G834N	Neutral	0.058
BRCA1	P38398-1.2	G834P	Neutral	0.101
BRCA1	P38398-1.2	G834Q	Neutral	0.162
BRCA1	P38398-1.2	G834R	Neutral	0.288
BRCA1	P38398-1.2	G834S	Neutral	0.036
BRCA1	P38398-1.2	G834T	Neutral	0.108
BRCA1	P38398-1.2	G834V	Neutral	0.182
BRCA1	P38398-1.2	G834W	Neutral	0.355
BRCA1	P38398-1.2	G834Y	Neutral	0.333
BRCA1	P38398-1.2	H835A	Neutral	0.006
BRCA1	P38398-1.2	H835C	Neutral	0.006
BRCA1	P38398-1.2	H835D	Neutral	0.003
BRCA1	P38398-1.2	H835E	Neutral	0.001
BRCA1	P38398-1.2	H835F	Neutral	0.002
BRCA1	P38398-1.2	H835G	Neutral	0.009
BRCA1	P38398-1.2	H835I	Neutral	0.003
BRCA1	P38398-1.2	H835K	Neutral	0.002
BRCA1	P38398-1.2	H835L	Neutral	0.003
BRCA1	P38398-1.2	H835M	Neutral	0.002
BRCA1	P38398-1.2	H835N	Neutral	0.001
BRCA1	P38398-1.2	H835P	Neutral	0.004
BRCA1	P38398-1.2	H835Q	Neutral	0.001
BRCA1	P38398-1.2	H835R	Neutral	0.002
BRCA1	P38398-1.2	H835S	Neutral	0.004
BRCA1	P38398-1.2	H835T	Neutral	0.004
BRCA1	P38398-1.2	H835V	Neutral	0.004
BRCA1	P38398-1.2	H835W	Neutral	0.005
BRCA1	P38398-1.2	H835Y	Neutral	0.001
BRCA1	P38398-1.2	E836A	Neutral	0.111
BRCA1	P38398-1.2	E836C	Neutral	0.194
BRCA1	P38398-1.2	E836D	Neutral	0.024
BRCA1	P38398-1.2	E836F	Neutral	0.15
BRCA1	P38398-1.2	E836G	Neutral	0.216
BRCA1	P38398-1.2	E836H	Neutral	0.04
BRCA1	P38398-1.2	E836I	Neutral	0.121
BRCA1	P38398-1.2	E836K	Neutral	0.041
BRCA1	P38398-1.2	E836L	Neutral	0.121
BRCA1	P38398-1.2	E836M	Neutral	0.088
BRCA1	P38398-1.2	E836N	Neutral	0.044
BRCA1	P38398-1.2	E836P	Neutral	0.069
BRCA1	P38398-1.2	E836Q	Neutral	0.018
BRCA1	P38398-1.2	E836R	Neutral	0.076
BRCA1	P38398-1.2	E836S	Neutral	0.071
BRCA1	P38398-1.2	E836T	Neutral	0.066
BRCA1	P38398-1.2	E836V	Neutral	0.071
BRCA1	P38398-1.2	E836W	Neutral	0.245
BRCA1	P38398-1.2	E836Y	Neutral	0.124
BRCA1	P38398-1.2	V837A	Neutral	0.139
BRCA1	P38398-1.2	V837C	Neutral	0.133
BRCA1	P38398-1.2	V837D	Neutral	0.216
BRCA1	P38398-1.2	V837E	Neutral	0.133
BRCA1	P38398-1.2	V837F	Neutral	0.163
BRCA1	P38398-1.2	V837G	Neutral	0.421
BRCA1	P38398-1.2	V837H	Neutral	0.215
BRCA1	P38398-1.2	V837I	Neutral	0.034
BRCA1	P38398-1.2	V837K	Neutral	0.214
BRCA1	P38398-1.2	V837L	Neutral	0.069
BRCA1	P38398-1.2	V837M	Neutral	0.069
BRCA1	P38398-1.2	V837N	Neutral	0.199
BRCA1	P38398-1.2	V837P	Neutral	0.168
BRCA1	P38398-1.2	V837Q	Neutral	0.148
BRCA1	P38398-1.2	V837R	Neutral	0.343
BRCA1	P38398-1.2	V837S	Neutral	0.225
BRCA1	P38398-1.2	V837T	Neutral	0.083
BRCA1	P38398-1.2	V837W	Neutral	0.428
BRCA1	P38398-1.2	V837Y	Neutral	0.183
BRCA1	P38398-1.2	N838A	Neutral	0.326
BRCA1	P38398-1.2	N838C	Neutral	0.311
BRCA1	P38398-1.2	N838D	Neutral	0.088
BRCA1	P38398-1.2	N838E	Neutral	0.143
BRCA1	P38398-1.2	N838F	Neutral	0.458
BRCA1	P38398-1.2	N838G	Neutral	0.264
BRCA1	P38398-1.2	N838H	Neutral	0.122
BRCA1	P38398-1.2	N838I	Neutral	0.398
BRCA1	P38398-1.2	N838K	Neutral	0.228
BRCA1	P38398-1.2	N838L	Neutral	0.399
BRCA1	P38398-1.2	N838M	Neutral	0.317
BRCA1	P38398-1.2	N838P	Neutral	0.224
BRCA1	P38398-1.2	N838Q	Neutral	0.156
BRCA1	P38398-1.2	N838R	Neutral	0.282
BRCA1	P38398-1.2	N838S	Neutral	0.125
BRCA1	P38398-1.2	N838T	Neutral	0.116
BRCA1	P38398-1.2	N838V	Neutral	0.305
BRCA1	P38398-1.2	N838W	Pathogenic	0.692
BRCA1	P38398-1.2	N838Y	Neutral	0.405
BRCA1	P38398-1.2	H839A	Neutral	0.433
BRCA1	P38398-1.2	H839C	Neutral	0.415
BRCA1	P38398-1.2	H839D	Neutral	0.235
BRCA1	P38398-1.2	H839E	Neutral	0.125
BRCA1	P38398-1.2	H839F	Neutral	0.195
BRCA1	P38398-1.2	H839G	Pathogenic	0.538
BRCA1	P38398-1.2	H839I	Neutral	0.282
BRCA1	P38398-1.2	H839K	Neutral	0.196
BRCA1	P38398-1.2	H839L	Neutral	0.282
BRCA1	P38398-1.2	H839M	Neutral	0.216
BRCA1	P38398-1.2	H839N	Neutral	0.117
BRCA1	P38398-1.2	H839P	Neutral	0.312
BRCA1	P38398-1.2	H839Q	Neutral	0.114
BRCA1	P38398-1.2	H839R	Neutral	0.185
BRCA1	P38398-1.2	H839S	Neutral	0.317
BRCA1	P38398-1.2	H839T	Neutral	0.3
BRCA1	P38398-1.2	H839V	Neutral	0.317
BRCA1	P38398-1.2	H839W	Neutral	0.391
BRCA1	P38398-1.2	H839Y	Neutral	0.086
BRCA1	P38398-1.2	S840A	Neutral	0.0
BRCA1	P38398-1.2	S840C	Neutral	0.001
BRCA1	P38398-1.2	S840D	Neutral	0.001
BRCA1	P38398-1.2	S840E	Neutral	0.001
BRCA1	P38398-1.2	S840F	Neutral	0.004
BRCA1	P38398-1.2	S840G	Neutral	0.001
BRCA1	P38398-1.2	S840H	Neutral	0.002
BRCA1	P38398-1.2	S840I	Neutral	0.003
BRCA1	P38398-1.2	S840K	Neutral	0.002
BRCA1	P38398-1.2	S840L	Neutral	0.003
BRCA1	P38398-1.2	S840M	Neutral	0.002
BRCA1	P38398-1.2	S840N	Neutral	0.001
BRCA1	P38398-1.2	S840P	Neutral	0.001
BRCA1	P38398-1.2	S840Q	Neutral	0.001
BRCA1	P38398-1.2	S840R	Neutral	0.004
BRCA1	P38398-1.2	S840T	Neutral	0.001
BRCA1	P38398-1.2	S840V	Neutral	0.002
BRCA1	P38398-1.2	S840W	Neutral	0.01
BRCA1	P38398-1.2	S840Y	Neutral	0.004
BRCA1	P38398-1.2	R841A	Neutral	0.43
BRCA1	P38398-1.2	R841C	Pathogenic	0.503
BRCA1	P38398-1.2	R841D	Neutral	0.394
BRCA1	P38398-1.2	R841E	Neutral	0.174
BRCA1	P38398-1.2	R841F	Neutral	0.251
BRCA1	P38398-1.2	R841G	Pathogenic	0.625
BRCA1	P38398-1.2	R841H	Neutral	0.145
BRCA1	P38398-1.2	R841I	Neutral	0.3
BRCA1	P38398-1.2	R841K	Neutral	0.054
BRCA1	P38398-1.2	R841L	Neutral	0.23
BRCA1	P38398-1.2	R841M	Neutral	0.173
BRCA1	P38398-1.2	R841N	Neutral	0.219
BRCA1	P38398-1.2	R841P	Neutral	0.393
BRCA1	P38398-1.2	R841Q	Neutral	0.115
BRCA1	P38398-1.2	R841S	Neutral	0.399
BRCA1	P38398-1.2	R841T	Neutral	0.298
BRCA1	P38398-1.2	R841V	Neutral	0.398
BRCA1	P38398-1.2	R841W	Neutral	0.258
BRCA1	P38398-1.2	R841Y	Neutral	0.172
BRCA1	P38398-1.2	E842A	Pathogenic	0.809
BRCA1	P38398-1.2	E842C	Pathogenic	0.891
BRCA1	P38398-1.2	E842D	Neutral	0.458
BRCA1	P38398-1.2	E842F	Pathogenic	0.856
BRCA1	P38398-1.2	E842G	Pathogenic	0.903
BRCA1	P38398-1.2	E842H	Pathogenic	0.586
BRCA1	P38398-1.2	E842I	Pathogenic	0.823
BRCA1	P38398-1.2	E842K	Pathogenic	0.591
BRCA1	P38398-1.2	E842L	Pathogenic	0.824
BRCA1	P38398-1.2	E842M	Pathogenic	0.766
BRCA1	P38398-1.2	E842N	Pathogenic	0.611
BRCA1	P38398-1.2	E842P	Pathogenic	0.715
BRCA1	P38398-1.2	E842Q	Neutral	0.386
BRCA1	P38398-1.2	E842R	Pathogenic	0.735
BRCA1	P38398-1.2	E842S	Pathogenic	0.721
BRCA1	P38398-1.2	E842T	Pathogenic	0.703
BRCA1	P38398-1.2	E842V	Pathogenic	0.72
BRCA1	P38398-1.2	E842W	Pathogenic	0.917
BRCA1	P38398-1.2	E842Y	Pathogenic	0.828
BRCA1	P38398-1.2	T843A	Neutral	0.063
BRCA1	P38398-1.2	T843C	Neutral	0.059
BRCA1	P38398-1.2	T843D	Neutral	0.053
BRCA1	P38398-1.2	T843E	Neutral	0.071
BRCA1	P38398-1.2	T843F	Neutral	0.162
BRCA1	P38398-1.2	T843G	Neutral	0.175
BRCA1	P38398-1.2	T843H	Neutral	0.12
BRCA1	P38398-1.2	T843I	Neutral	0.095
BRCA1	P38398-1.2	T843K	Neutral	0.119
BRCA1	P38398-1.2	T843L	Neutral	0.095
BRCA1	P38398-1.2	T843M	Neutral	0.096
BRCA1	P38398-1.2	T843N	Neutral	0.038
BRCA1	P38398-1.2	T843P	Neutral	0.054
BRCA1	P38398-1.2	T843Q	Neutral	0.079
BRCA1	P38398-1.2	T843R	Neutral	0.153
BRCA1	P38398-1.2	T843S	Neutral	0.039
BRCA1	P38398-1.2	T843V	Neutral	0.046
BRCA1	P38398-1.2	T843W	Neutral	0.263
BRCA1	P38398-1.2	T843Y	Neutral	0.183
BRCA1	P38398-1.2	S844A	Neutral	0.002
BRCA1	P38398-1.2	S844C	Neutral	0.005
BRCA1	P38398-1.2	S844D	Neutral	0.004
BRCA1	P38398-1.2	S844E	Neutral	0.006
BRCA1	P38398-1.2	S844F	Neutral	0.022
BRCA1	P38398-1.2	S844G	Neutral	0.005
BRCA1	P38398-1.2	S844H	Neutral	0.011
BRCA1	P38398-1.2	S844I	Neutral	0.017
BRCA1	P38398-1.2	S844K	Neutral	0.011
BRCA1	P38398-1.2	S844L	Neutral	0.017
BRCA1	P38398-1.2	S844M	Neutral	0.012
BRCA1	P38398-1.2	S844N	Neutral	0.003
BRCA1	P38398-1.2	S844P	Neutral	0.006
BRCA1	P38398-1.2	S844Q	Neutral	0.007
BRCA1	P38398-1.2	S844R	Neutral	0.02
BRCA1	P38398-1.2	S844T	Neutral	0.003
BRCA1	P38398-1.2	S844V	Neutral	0.011
BRCA1	P38398-1.2	S844W	Neutral	0.055
BRCA1	P38398-1.2	S844Y	Neutral	0.025
BRCA1	P38398-1.2	I845A	Neutral	0.023
BRCA1	P38398-1.2	I845C	Neutral	0.015
BRCA1	P38398-1.2	I845D	Neutral	0.027
BRCA1	P38398-1.2	I845E	Neutral	0.018
BRCA1	P38398-1.2	I845F	Neutral	0.006
BRCA1	P38398-1.2	I845G	Neutral	0.095
BRCA1	P38398-1.2	I845H	Neutral	0.015
BRCA1	P38398-1.2	I845K	Neutral	0.017
BRCA1	P38398-1.2	I845L	Neutral	0.002
BRCA1	P38398-1.2	I845M	Neutral	0.003
BRCA1	P38398-1.2	I845N	Neutral	0.024
BRCA1	P38398-1.2	I845P	Neutral	0.028
BRCA1	P38398-1.2	I845Q	Neutral	0.017
BRCA1	P38398-1.2	I845R	Neutral	0.022
BRCA1	P38398-1.2	I845S	Neutral	0.028
BRCA1	P38398-1.2	I845T	Neutral	0.013
BRCA1	P38398-1.2	I845V	Neutral	0.002
BRCA1	P38398-1.2	I845W	Neutral	0.032
BRCA1	P38398-1.2	I845Y	Neutral	0.01
BRCA1	P38398-1.2	E846A	Pathogenic	0.81
BRCA1	P38398-1.2	E846C	Pathogenic	0.891
BRCA1	P38398-1.2	E846D	Neutral	0.46
BRCA1	P38398-1.2	E846F	Pathogenic	0.857
BRCA1	P38398-1.2	E846G	Pathogenic	0.904
BRCA1	P38398-1.2	E846H	Pathogenic	0.588
BRCA1	P38398-1.2	E846I	Pathogenic	0.825
BRCA1	P38398-1.2	E846K	Pathogenic	0.593
BRCA1	P38398-1.2	E846L	Pathogenic	0.825
BRCA1	P38398-1.2	E846M	Pathogenic	0.768
BRCA1	P38398-1.2	E846N	Pathogenic	0.612
BRCA1	P38398-1.2	E846P	Pathogenic	0.717
BRCA1	P38398-1.2	E846Q	Neutral	0.388
BRCA1	P38398-1.2	E846R	Pathogenic	0.737
BRCA1	P38398-1.2	E846S	Pathogenic	0.723
BRCA1	P38398-1.2	E846T	Pathogenic	0.705
BRCA1	P38398-1.2	E846V	Pathogenic	0.721
BRCA1	P38398-1.2	E846W	Pathogenic	0.917
BRCA1	P38398-1.2	E846Y	Pathogenic	0.829
BRCA1	P38398-1.2	M847A	Pathogenic	0.517
BRCA1	P38398-1.2	M847C	Neutral	0.416
BRCA1	P38398-1.2	M847D	Pathogenic	0.56
BRCA1	P38398-1.2	M847E	Neutral	0.373
BRCA1	P38398-1.2	M847F	Neutral	0.212
BRCA1	P38398-1.2	M847G	Pathogenic	0.771
BRCA1	P38398-1.2	M847H	Neutral	0.331
BRCA1	P38398-1.2	M847I	Neutral	0.128
BRCA1	P38398-1.2	M847K	Neutral	0.273
BRCA1	P38398-1.2	M847L	Neutral	0.093
BRCA1	P38398-1.2	M847N	Neutral	0.443
BRCA1	P38398-1.2	M847P	Neutral	0.482
BRCA1	P38398-1.2	M847Q	Neutral	0.206
BRCA1	P38398-1.2	M847R	Neutral	0.334
BRCA1	P38398-1.2	M847S	Neutral	0.482
BRCA1	P38398-1.2	M847T	Neutral	0.375
BRCA1	P38398-1.2	M847V	Neutral	0.185
BRCA1	P38398-1.2	M847W	Neutral	0.417
BRCA1	P38398-1.2	M847Y	Neutral	0.308
BRCA1	P38398-1.2	E848A	Pathogenic	0.965
BRCA1	P38398-1.2	E848C	Pathogenic	0.982
BRCA1	P38398-1.2	E848D	Pathogenic	0.848
BRCA1	P38398-1.2	E848F	Pathogenic	0.975
BRCA1	P38398-1.2	E848G	Pathogenic	0.984
BRCA1	P38398-1.2	E848H	Pathogenic	0.904
BRCA1	P38398-1.2	E848I	Pathogenic	0.969
BRCA1	P38398-1.2	E848K	Pathogenic	0.905
BRCA1	P38398-1.2	E848L	Pathogenic	0.969
BRCA1	P38398-1.2	E848M	Pathogenic	0.956
BRCA1	P38398-1.2	E848N	Pathogenic	0.912
BRCA1	P38398-1.2	E848P	Pathogenic	0.943
BRCA1	P38398-1.2	E848Q	Pathogenic	0.807
BRCA1	P38398-1.2	E848R	Pathogenic	0.948
BRCA1	P38398-1.2	E848S	Pathogenic	0.945
BRCA1	P38398-1.2	E848T	Pathogenic	0.94
BRCA1	P38398-1.2	E848V	Pathogenic	0.944
BRCA1	P38398-1.2	E848W	Pathogenic	0.986
BRCA1	P38398-1.2	E848Y	Pathogenic	0.97
BRCA1	P38398-1.2	E849A	Pathogenic	0.593
BRCA1	P38398-1.2	E849C	Pathogenic	0.737
BRCA1	P38398-1.2	E849D	Neutral	0.226
BRCA1	P38398-1.2	E849F	Pathogenic	0.673
BRCA1	P38398-1.2	E849G	Pathogenic	0.763
BRCA1	P38398-1.2	E849H	Neutral	0.328
BRCA1	P38398-1.2	E849I	Pathogenic	0.617
BRCA1	P38398-1.2	E849K	Neutral	0.333
BRCA1	P38398-1.2	E849L	Pathogenic	0.617
BRCA1	P38398-1.2	E849M	Pathogenic	0.531
BRCA1	P38398-1.2	E849N	Neutral	0.351
BRCA1	P38398-1.2	E849P	Neutral	0.464
BRCA1	P38398-1.2	E849Q	Neutral	0.178
BRCA1	P38398-1.2	E849R	Neutral	0.489
BRCA1	P38398-1.2	E849S	Neutral	0.471
BRCA1	P38398-1.2	E849T	Neutral	0.45
BRCA1	P38398-1.2	E849V	Neutral	0.47
BRCA1	P38398-1.2	E849W	Pathogenic	0.791
BRCA1	P38398-1.2	E849Y	Pathogenic	0.624
BRCA1	P38398-1.2	S850A	Pathogenic	0.667
BRCA1	P38398-1.2	S850C	Pathogenic	0.827
BRCA1	P38398-1.2	S850D	Pathogenic	0.789
BRCA1	P38398-1.2	S850E	Pathogenic	0.848
BRCA1	P38398-1.2	S850F	Pathogenic	0.953
BRCA1	P38398-1.2	S850G	Pathogenic	0.816
BRCA1	P38398-1.2	S850H	Pathogenic	0.908
BRCA1	P38398-1.2	S850I	Pathogenic	0.94
BRCA1	P38398-1.2	S850K	Pathogenic	0.908
BRCA1	P38398-1.2	S850L	Pathogenic	0.94
BRCA1	P38398-1.2	S850M	Pathogenic	0.917
BRCA1	P38398-1.2	S850N	Pathogenic	0.744
BRCA1	P38398-1.2	S850P	Pathogenic	0.84
BRCA1	P38398-1.2	S850Q	Pathogenic	0.863
BRCA1	P38398-1.2	S850R	Pathogenic	0.95
BRCA1	P38398-1.2	S850T	Pathogenic	0.733
BRCA1	P38398-1.2	S850V	Pathogenic	0.913
BRCA1	P38398-1.2	S850W	Pathogenic	0.982
BRCA1	P38398-1.2	S850Y	Pathogenic	0.959
BRCA1	P38398-1.2	E851A	Pathogenic	0.978
BRCA1	P38398-1.2	E851C	Pathogenic	0.988
BRCA1	P38398-1.2	E851D	Pathogenic	0.897
BRCA1	P38398-1.2	E851F	Pathogenic	0.984
BRCA1	P38398-1.2	E851G	Pathogenic	0.99
BRCA1	P38398-1.2	E851H	Pathogenic	0.936
BRCA1	P38398-1.2	E851I	Pathogenic	0.98
BRCA1	P38398-1.2	E851K	Pathogenic	0.937
BRCA1	P38398-1.2	E851L	Pathogenic	0.98
BRCA1	P38398-1.2	E851M	Pathogenic	0.971
BRCA1	P38398-1.2	E851N	Pathogenic	0.942
BRCA1	P38398-1.2	E851P	Pathogenic	0.963
BRCA1	P38398-1.2	E851Q	Pathogenic	0.867
BRCA1	P38398-1.2	E851R	Pathogenic	0.966
BRCA1	P38398-1.2	E851S	Pathogenic	0.964
BRCA1	P38398-1.2	E851T	Pathogenic	0.961
BRCA1	P38398-1.2	E851V	Pathogenic	0.964
BRCA1	P38398-1.2	E851W	Pathogenic	0.991
BRCA1	P38398-1.2	E851Y	Pathogenic	0.98
BRCA1	P38398-1.2	L852A	Pathogenic	0.98
BRCA1	P38398-1.2	L852C	Pathogenic	0.97
BRCA1	P38398-1.2	L852D	Pathogenic	0.988
BRCA1	P38398-1.2	L852E	Pathogenic	0.975
BRCA1	P38398-1.2	L852F	Pathogenic	0.926
BRCA1	P38398-1.2	L852G	Pathogenic	0.996
BRCA1	P38398-1.2	L852H	Pathogenic	0.97
BRCA1	P38398-1.2	L852I	Pathogenic	0.827
BRCA1	P38398-1.2	L852K	Pathogenic	0.961
BRCA1	P38398-1.2	L852M	Pathogenic	0.826
BRCA1	P38398-1.2	L852N	Pathogenic	0.981
BRCA1	P38398-1.2	L852P	Pathogenic	0.984
BRCA1	P38398-1.2	L852Q	Pathogenic	0.961
BRCA1	P38398-1.2	L852R	Pathogenic	0.971
BRCA1	P38398-1.2	L852S	Pathogenic	0.984
BRCA1	P38398-1.2	L852T	Pathogenic	0.965
BRCA1	P38398-1.2	L852V	Pathogenic	0.912
BRCA1	P38398-1.2	L852W	Pathogenic	0.98
BRCA1	P38398-1.2	L852Y	Pathogenic	0.953
BRCA1	P38398-1.2	D853A	Pathogenic	0.99
BRCA1	P38398-1.2	D853C	Pathogenic	0.989
BRCA1	P38398-1.2	D853E	Pathogenic	0.954
BRCA1	P38398-1.2	D853F	Pathogenic	0.995
BRCA1	P38398-1.2	D853G	Pathogenic	0.991
BRCA1	P38398-1.2	D853H	Pathogenic	0.987
BRCA1	P38398-1.2	D853I	Pathogenic	0.994
BRCA1	P38398-1.2	D853K	Pathogenic	0.991
BRCA1	P38398-1.2	D853L	Pathogenic	0.996
BRCA1	P38398-1.2	D853M	Pathogenic	0.994
BRCA1	P38398-1.2	D853N	Pathogenic	0.957
BRCA1	P38398-1.2	D853P	Pathogenic	0.976
BRCA1	P38398-1.2	D853Q	Pathogenic	0.98
BRCA1	P38398-1.2	D853R	Pathogenic	0.995
BRCA1	P38398-1.2	D853S	Pathogenic	0.977
BRCA1	P38398-1.2	D853T	Pathogenic	0.977
BRCA1	P38398-1.2	D853V	Pathogenic	0.991
BRCA1	P38398-1.2	D853W	Pathogenic	0.998
BRCA1	P38398-1.2	D853Y	Pathogenic	0.996
BRCA1	P38398-1.2	A854C	Pathogenic	0.632
BRCA1	P38398-1.2	A854D	Pathogenic	0.798
BRCA1	P38398-1.2	A854E	Pathogenic	0.804
BRCA1	P38398-1.2	A854F	Pathogenic	0.912
BRCA1	P38398-1.2	A854G	Pathogenic	0.634
BRCA1	P38398-1.2	A854H	Pathogenic	0.88
BRCA1	P38398-1.2	A854I	Pathogenic	0.85
BRCA1	P38398-1.2	A854K	Pathogenic	0.879
BRCA1	P38398-1.2	A854L	Pathogenic	0.85
BRCA1	P38398-1.2	A854M	Pathogenic	0.851
BRCA1	P38398-1.2	A854N	Pathogenic	0.815
BRCA1	P38398-1.2	A854P	Pathogenic	0.731
BRCA1	P38398-1.2	A854Q	Pathogenic	0.822
BRCA1	P38398-1.2	A854R	Pathogenic	0.906
BRCA1	P38398-1.2	A854S	Neutral	0.474
BRCA1	P38398-1.2	A854T	Pathogenic	0.67
BRCA1	P38398-1.2	A854V	Pathogenic	0.723
BRCA1	P38398-1.2	A854W	Pathogenic	0.965
BRCA1	P38398-1.2	A854Y	Pathogenic	0.923
BRCA1	P38398-1.2	Q855A	Pathogenic	0.992
BRCA1	P38398-1.2	Q855C	Pathogenic	0.994
BRCA1	P38398-1.2	Q855D	Pathogenic	0.98
BRCA1	P38398-1.2	Q855E	Pathogenic	0.941
BRCA1	P38398-1.2	Q855F	Pathogenic	0.993
BRCA1	P38398-1.2	Q855G	Pathogenic	0.996
BRCA1	P38398-1.2	Q855H	Pathogenic	0.97
BRCA1	P38398-1.2	Q855I	Pathogenic	0.991
BRCA1	P38398-1.2	Q855K	Pathogenic	0.97
BRCA1	P38398-1.2	Q855L	Pathogenic	0.987
BRCA1	P38398-1.2	Q855M	Pathogenic	0.973
BRCA1	P38398-1.2	Q855N	Pathogenic	0.978
BRCA1	P38398-1.2	Q855P	Pathogenic	0.986
BRCA1	P38398-1.2	Q855R	Pathogenic	0.977
BRCA1	P38398-1.2	Q855S	Pathogenic	0.987
BRCA1	P38398-1.2	Q855T	Pathogenic	0.985
BRCA1	P38398-1.2	Q855V	Pathogenic	0.986
BRCA1	P38398-1.2	Q855W	Pathogenic	0.994
BRCA1	P38398-1.2	Q855Y	Pathogenic	0.987
BRCA1	P38398-1.2	Y856A	Pathogenic	0.958
BRCA1	P38398-1.2	Y856C	Pathogenic	0.938
BRCA1	P38398-1.2	Y856D	Pathogenic	0.95
BRCA1	P38398-1.2	Y856E	Pathogenic	0.898
BRCA1	P38398-1.2	Y856F	Neutral	0.449
BRCA1	P38398-1.2	Y856G	Pathogenic	0.98
BRCA1	P38398-1.2	Y856H	Pathogenic	0.631
BRCA1	P38398-1.2	Y856I	Pathogenic	0.817
BRCA1	P38398-1.2	Y856K	Pathogenic	0.831
BRCA1	P38398-1.2	Y856L	Pathogenic	0.817
BRCA1	P38398-1.2	Y856M	Pathogenic	0.819
BRCA1	P38398-1.2	Y856N	Pathogenic	0.922
BRCA1	P38398-1.2	Y856P	Pathogenic	0.952
BRCA1	P38398-1.2	Y856Q	Pathogenic	0.847
BRCA1	P38398-1.2	Y856R	Pathogenic	0.834
BRCA1	P38398-1.2	Y856S	Pathogenic	0.952
BRCA1	P38398-1.2	Y856T	Pathogenic	0.928
BRCA1	P38398-1.2	Y856V	Pathogenic	0.873
BRCA1	P38398-1.2	Y856W	Pathogenic	0.624
BRCA1	P38398-1.2	L857A	Pathogenic	0.985
BRCA1	P38398-1.2	L857C	Pathogenic	0.978
BRCA1	P38398-1.2	L857D	Pathogenic	0.991
BRCA1	P38398-1.2	L857E	Pathogenic	0.982
BRCA1	P38398-1.2	L857F	Pathogenic	0.945
BRCA1	P38398-1.2	L857G	Pathogenic	0.997
BRCA1	P38398-1.2	L857H	Pathogenic	0.978
BRCA1	P38398-1.2	L857I	Pathogenic	0.867
BRCA1	P38398-1.2	L857K	Pathogenic	0.971
BRCA1	P38398-1.2	L857M	Pathogenic	0.866
BRCA1	P38398-1.2	L857N	Pathogenic	0.986
BRCA1	P38398-1.2	L857P	Pathogenic	0.988
BRCA1	P38398-1.2	L857Q	Pathogenic	0.971
BRCA1	P38398-1.2	L857R	Pathogenic	0.978
BRCA1	P38398-1.2	L857S	Pathogenic	0.988
BRCA1	P38398-1.2	L857T	Pathogenic	0.974
BRCA1	P38398-1.2	L857V	Pathogenic	0.934
BRCA1	P38398-1.2	L857W	Pathogenic	0.985
BRCA1	P38398-1.2	L857Y	Pathogenic	0.966
BRCA1	P38398-1.2	Q858A	Pathogenic	0.869
BRCA1	P38398-1.2	Q858C	Pathogenic	0.899
BRCA1	P38398-1.2	Q858D	Pathogenic	0.729
BRCA1	P38398-1.2	Q858E	Neutral	0.466
BRCA1	P38398-1.2	Q858F	Pathogenic	0.882
BRCA1	P38398-1.2	Q858G	Pathogenic	0.936
BRCA1	P38398-1.2	Q858H	Pathogenic	0.639
BRCA1	P38398-1.2	Q858I	Pathogenic	0.854
BRCA1	P38398-1.2	Q858K	Pathogenic	0.641
BRCA1	P38398-1.2	Q858L	Pathogenic	0.803
BRCA1	P38398-1.2	Q858M	Pathogenic	0.665
BRCA1	P38398-1.2	Q858N	Pathogenic	0.707
BRCA1	P38398-1.2	Q858P	Pathogenic	0.797
BRCA1	P38398-1.2	Q858R	Pathogenic	0.704
BRCA1	P38398-1.2	Q858S	Pathogenic	0.802
BRCA1	P38398-1.2	Q858T	Pathogenic	0.788
BRCA1	P38398-1.2	Q858V	Pathogenic	0.801
BRCA1	P38398-1.2	Q858W	Pathogenic	0.905
BRCA1	P38398-1.2	Q858Y	Pathogenic	0.807
BRCA1	P38398-1.2	N859A	Pathogenic	0.801
BRCA1	P38398-1.2	N859C	Pathogenic	0.79
BRCA1	P38398-1.2	N859D	Neutral	0.446
BRCA1	P38398-1.2	N859E	Pathogenic	0.581
BRCA1	P38398-1.2	N859F	Pathogenic	0.876
BRCA1	P38398-1.2	N859G	Pathogenic	0.749
BRCA1	P38398-1.2	N859H	Pathogenic	0.537
BRCA1	P38398-1.2	N859I	Pathogenic	0.846
BRCA1	P38398-1.2	N859K	Pathogenic	0.71
BRCA1	P38398-1.2	N859L	Pathogenic	0.847
BRCA1	P38398-1.2	N859M	Pathogenic	0.795
BRCA1	P38398-1.2	N859P	Pathogenic	0.706
BRCA1	P38398-1.2	N859Q	Pathogenic	0.606
BRCA1	P38398-1.2	N859R	Pathogenic	0.766
BRCA1	P38398-1.2	N859S	Pathogenic	0.544
BRCA1	P38398-1.2	N859T	Pathogenic	0.522
BRCA1	P38398-1.2	N859V	Pathogenic	0.785
BRCA1	P38398-1.2	N859W	Pathogenic	0.949
BRCA1	P38398-1.2	N859Y	Pathogenic	0.85
BRCA1	P38398-1.2	T860A	Pathogenic	0.741
BRCA1	P38398-1.2	T860C	Pathogenic	0.727
BRCA1	P38398-1.2	T860D	Pathogenic	0.703
BRCA1	P38398-1.2	T860E	Pathogenic	0.764
BRCA1	P38398-1.2	T860F	Pathogenic	0.892
BRCA1	P38398-1.2	T860G	Pathogenic	0.9
BRCA1	P38398-1.2	T860H	Pathogenic	0.853
BRCA1	P38398-1.2	T860I	Pathogenic	0.817
BRCA1	P38398-1.2	T860K	Pathogenic	0.852
BRCA1	P38398-1.2	T860L	Pathogenic	0.818
BRCA1	P38398-1.2	T860M	Pathogenic	0.819
BRCA1	P38398-1.2	T860N	Pathogenic	0.628
BRCA1	P38398-1.2	T860P	Pathogenic	0.71
BRCA1	P38398-1.2	T860Q	Pathogenic	0.785
BRCA1	P38398-1.2	T860R	Pathogenic	0.885
BRCA1	P38398-1.2	T860S	Pathogenic	0.634
BRCA1	P38398-1.2	T860V	Pathogenic	0.673
BRCA1	P38398-1.2	T860W	Pathogenic	0.938
BRCA1	P38398-1.2	T860Y	Pathogenic	0.905
BRCA1	P38398-1.2	F861A	Pathogenic	0.996
BRCA1	P38398-1.2	F861C	Pathogenic	0.994
BRCA1	P38398-1.2	F861D	Pathogenic	0.995
BRCA1	P38398-1.2	F861E	Pathogenic	0.993
BRCA1	P38398-1.2	F861G	Pathogenic	0.998
BRCA1	P38398-1.2	F861H	Pathogenic	0.982
BRCA1	P38398-1.2	F861I	Pathogenic	0.971
BRCA1	P38398-1.2	F861K	Pathogenic	0.987
BRCA1	P38398-1.2	F861L	Pathogenic	0.971
BRCA1	P38398-1.2	F861M	Pathogenic	0.971
BRCA1	P38398-1.2	F861N	Pathogenic	0.994
BRCA1	P38398-1.2	F861P	Pathogenic	0.997
BRCA1	P38398-1.2	F861Q	Pathogenic	0.992
BRCA1	P38398-1.2	F861R	Pathogenic	0.99
BRCA1	P38398-1.2	F861S	Pathogenic	0.995
BRCA1	P38398-1.2	F861T	Pathogenic	0.993
BRCA1	P38398-1.2	F861V	Pathogenic	0.986
BRCA1	P38398-1.2	F861W	Pathogenic	0.971
BRCA1	P38398-1.2	F861Y	Pathogenic	0.909
BRCA1	P38398-1.2	K862A	Pathogenic	0.546
BRCA1	P38398-1.2	K862C	Pathogenic	0.617
BRCA1	P38398-1.2	K862D	Neutral	0.419
BRCA1	P38398-1.2	K862E	Neutral	0.189
BRCA1	P38398-1.2	K862F	Neutral	0.348
BRCA1	P38398-1.2	K862G	Pathogenic	0.727
BRCA1	P38398-1.2	K862H	Neutral	0.28
BRCA1	P38398-1.2	K862I	Neutral	0.406
BRCA1	P38398-1.2	K862L	Neutral	0.322
BRCA1	P38398-1.2	K862M	Neutral	0.25
BRCA1	P38398-1.2	K862N	Neutral	0.309
BRCA1	P38398-1.2	K862P	Neutral	0.417
BRCA1	P38398-1.2	K862Q	Neutral	0.171
BRCA1	P38398-1.2	K862R	Neutral	0.109
BRCA1	P38398-1.2	K862S	Neutral	0.424
BRCA1	P38398-1.2	K862T	Neutral	0.403
BRCA1	P38398-1.2	K862V	Neutral	0.423
BRCA1	P38398-1.2	K862W	Neutral	0.497
BRCA1	P38398-1.2	K862Y	Neutral	0.301
BRCA1	P38398-1.2	V863A	Neutral	0.04
BRCA1	P38398-1.2	V863C	Neutral	0.038
BRCA1	P38398-1.2	V863D	Neutral	0.067
BRCA1	P38398-1.2	V863E	Neutral	0.038
BRCA1	P38398-1.2	V863F	Neutral	0.048
BRCA1	P38398-1.2	V863G	Neutral	0.159
BRCA1	P38398-1.2	V863H	Neutral	0.066
BRCA1	P38398-1.2	V863I	Neutral	0.009
BRCA1	P38398-1.2	V863K	Neutral	0.066
BRCA1	P38398-1.2	V863L	Neutral	0.019
BRCA1	P38398-1.2	V863M	Neutral	0.019
BRCA1	P38398-1.2	V863N	Neutral	0.06
BRCA1	P38398-1.2	V863P	Neutral	0.05
BRCA1	P38398-1.2	V863Q	Neutral	0.043
BRCA1	P38398-1.2	V863R	Neutral	0.119
BRCA1	P38398-1.2	V863S	Neutral	0.07
BRCA1	P38398-1.2	V863T	Neutral	0.023
BRCA1	P38398-1.2	V863W	Neutral	0.162
BRCA1	P38398-1.2	V863Y	Neutral	0.055
BRCA1	P38398-1.2	S864A	Pathogenic	0.906
BRCA1	P38398-1.2	S864C	Pathogenic	0.958
BRCA1	P38398-1.2	S864D	Pathogenic	0.947
BRCA1	P38398-1.2	S864E	Pathogenic	0.964
BRCA1	P38398-1.2	S864F	Pathogenic	0.99
BRCA1	P38398-1.2	S864G	Pathogenic	0.955
BRCA1	P38398-1.2	S864H	Pathogenic	0.979
BRCA1	P38398-1.2	S864I	Pathogenic	0.987
BRCA1	P38398-1.2	S864K	Pathogenic	0.979
BRCA1	P38398-1.2	S864L	Pathogenic	0.987
BRCA1	P38398-1.2	S864M	Pathogenic	0.982
BRCA1	P38398-1.2	S864N	Pathogenic	0.933
BRCA1	P38398-1.2	S864P	Pathogenic	0.962
BRCA1	P38398-1.2	S864Q	Pathogenic	0.968
BRCA1	P38398-1.2	S864R	Pathogenic	0.989
BRCA1	P38398-1.2	S864T	Pathogenic	0.929
BRCA1	P38398-1.2	S864V	Pathogenic	0.98
BRCA1	P38398-1.2	S864W	Pathogenic	0.996
BRCA1	P38398-1.2	S864Y	Pathogenic	0.991
BRCA1	P38398-1.2	K865A	Pathogenic	0.918
BRCA1	P38398-1.2	K865C	Pathogenic	0.938
BRCA1	P38398-1.2	K865D	Pathogenic	0.87
BRCA1	P38398-1.2	K865E	Pathogenic	0.684
BRCA1	P38398-1.2	K865F	Pathogenic	0.833
BRCA1	P38398-1.2	K865G	Pathogenic	0.961
BRCA1	P38398-1.2	K865H	Pathogenic	0.784
BRCA1	P38398-1.2	K865I	Pathogenic	0.864
BRCA1	P38398-1.2	K865L	Pathogenic	0.816
BRCA1	P38398-1.2	K865M	Pathogenic	0.756
BRCA1	P38398-1.2	K865N	Pathogenic	0.806
BRCA1	P38398-1.2	K865P	Pathogenic	0.87
BRCA1	P38398-1.2	K865Q	Pathogenic	0.658
BRCA1	P38398-1.2	K865R	Pathogenic	0.532
BRCA1	P38398-1.2	K865S	Pathogenic	0.873
BRCA1	P38398-1.2	K865T	Pathogenic	0.863
BRCA1	P38398-1.2	K865V	Pathogenic	0.872
BRCA1	P38398-1.2	K865W	Pathogenic	0.902
BRCA1	P38398-1.2	K865Y	Pathogenic	0.801
BRCA1	P38398-1.2	R866A	Pathogenic	0.996
BRCA1	P38398-1.2	R866C	Pathogenic	0.997
BRCA1	P38398-1.2	R866D	Pathogenic	0.995
BRCA1	P38398-1.2	R866E	Pathogenic	0.984
BRCA1	P38398-1.2	R866F	Pathogenic	0.99
BRCA1	P38398-1.2	R866G	Pathogenic	0.998
BRCA1	P38398-1.2	R866H	Pathogenic	0.981
BRCA1	P38398-1.2	R866I	Pathogenic	0.992
BRCA1	P38398-1.2	R866K	Pathogenic	0.945
BRCA1	P38398-1.2	R866L	Pathogenic	0.989
BRCA1	P38398-1.2	R866M	Pathogenic	0.984
BRCA1	P38398-1.2	R866N	Pathogenic	0.988
BRCA1	P38398-1.2	R866P	Pathogenic	0.995
BRCA1	P38398-1.2	R866Q	Pathogenic	0.975
BRCA1	P38398-1.2	R866S	Pathogenic	0.995
BRCA1	P38398-1.2	R866T	Pathogenic	0.992
BRCA1	P38398-1.2	R866V	Pathogenic	0.995
BRCA1	P38398-1.2	R866W	Pathogenic	0.99
BRCA1	P38398-1.2	R866Y	Pathogenic	0.984
BRCA1	P38398-1.2	Q867A	Pathogenic	0.949
BRCA1	P38398-1.2	Q867C	Pathogenic	0.961
BRCA1	P38398-1.2	Q867D	Pathogenic	0.883
BRCA1	P38398-1.2	Q867E	Pathogenic	0.71
BRCA1	P38398-1.2	Q867F	Pathogenic	0.954
BRCA1	P38398-1.2	Q867G	Pathogenic	0.976
BRCA1	P38398-1.2	Q867H	Pathogenic	0.832
BRCA1	P38398-1.2	Q867I	Pathogenic	0.942
BRCA1	P38398-1.2	Q867K	Pathogenic	0.833
BRCA1	P38398-1.2	Q867L	Pathogenic	0.919
BRCA1	P38398-1.2	Q867M	Pathogenic	0.847
BRCA1	P38398-1.2	Q867N	Pathogenic	0.871
BRCA1	P38398-1.2	Q867P	Pathogenic	0.917
BRCA1	P38398-1.2	Q867R	Pathogenic	0.869
BRCA1	P38398-1.2	Q867S	Pathogenic	0.919
BRCA1	P38398-1.2	Q867T	Pathogenic	0.912
BRCA1	P38398-1.2	Q867V	Pathogenic	0.918
BRCA1	P38398-1.2	Q867W	Pathogenic	0.964
BRCA1	P38398-1.2	Q867Y	Pathogenic	0.921
BRCA1	P38398-1.2	S868A	Pathogenic	0.541
BRCA1	P38398-1.2	S868C	Pathogenic	0.738
BRCA1	P38398-1.2	S868D	Pathogenic	0.687
BRCA1	P38398-1.2	S868E	Pathogenic	0.767
BRCA1	P38398-1.2	S868F	Pathogenic	0.922
BRCA1	P38398-1.2	S868G	Pathogenic	0.723
BRCA1	P38398-1.2	S868H	Pathogenic	0.854
BRCA1	P38398-1.2	S868I	Pathogenic	0.903
BRCA1	P38398-1.2	S868K	Pathogenic	0.853
BRCA1	P38398-1.2	S868L	Pathogenic	0.903
BRCA1	P38398-1.2	S868M	Pathogenic	0.867
BRCA1	P38398-1.2	S868N	Pathogenic	0.631
BRCA1	P38398-1.2	S868P	Pathogenic	0.756
BRCA1	P38398-1.2	S868Q	Pathogenic	0.787
BRCA1	P38398-1.2	S868R	Pathogenic	0.918
BRCA1	P38398-1.2	S868T	Pathogenic	0.617
BRCA1	P38398-1.2	S868V	Pathogenic	0.86
BRCA1	P38398-1.2	S868W	Pathogenic	0.969
BRCA1	P38398-1.2	S868Y	Pathogenic	0.932
BRCA1	P38398-1.2	F869A	Pathogenic	0.998
BRCA1	P38398-1.2	F869C	Pathogenic	0.997
BRCA1	P38398-1.2	F869D	Pathogenic	0.998
BRCA1	P38398-1.2	F869E	Pathogenic	0.996
BRCA1	P38398-1.2	F869G	Pathogenic	0.999
BRCA1	P38398-1.2	F869H	Pathogenic	0.991
BRCA1	P38398-1.2	F869I	Pathogenic	0.986
BRCA1	P38398-1.2	F869K	Pathogenic	0.994
BRCA1	P38398-1.2	F869L	Pathogenic	0.986
BRCA1	P38398-1.2	F869M	Pathogenic	0.986
BRCA1	P38398-1.2	F869N	Pathogenic	0.997
BRCA1	P38398-1.2	F869P	Pathogenic	0.998
BRCA1	P38398-1.2	F869Q	Pathogenic	0.996
BRCA1	P38398-1.2	F869R	Pathogenic	0.995
BRCA1	P38398-1.2	F869S	Pathogenic	0.998
BRCA1	P38398-1.2	F869T	Pathogenic	0.996
BRCA1	P38398-1.2	F869V	Pathogenic	0.994
BRCA1	P38398-1.2	F869W	Pathogenic	0.986
BRCA1	P38398-1.2	F869Y	Pathogenic	0.954
BRCA1	P38398-1.2	A870C	Pathogenic	0.939
BRCA1	P38398-1.2	A870D	Pathogenic	0.972
BRCA1	P38398-1.2	A870E	Pathogenic	0.973
BRCA1	P38398-1.2	A870F	Pathogenic	0.989
BRCA1	P38398-1.2	A870G	Pathogenic	0.939
BRCA1	P38398-1.2	A870H	Pathogenic	0.985
BRCA1	P38398-1.2	A870I	Pathogenic	0.981
BRCA1	P38398-1.2	A870K	Pathogenic	0.985
BRCA1	P38398-1.2	A870L	Pathogenic	0.981
BRCA1	P38398-1.2	A870M	Pathogenic	0.981
BRCA1	P38398-1.2	A870N	Pathogenic	0.975
BRCA1	P38398-1.2	A870P	Pathogenic	0.96
BRCA1	P38398-1.2	A870Q	Pathogenic	0.976
BRCA1	P38398-1.2	A870R	Pathogenic	0.989
BRCA1	P38398-1.2	A870S	Pathogenic	0.89
BRCA1	P38398-1.2	A870T	Pathogenic	0.948
BRCA1	P38398-1.2	A870V	Pathogenic	0.959
BRCA1	P38398-1.2	A870W	Pathogenic	0.996
BRCA1	P38398-1.2	A870Y	Pathogenic	0.991
BRCA1	P38398-1.2	P871A	Pathogenic	0.729
BRCA1	P38398-1.2	P871C	Pathogenic	0.785
BRCA1	P38398-1.2	P871D	Pathogenic	0.617
BRCA1	P38398-1.2	P871E	Pathogenic	0.707
BRCA1	P38398-1.2	P871F	Pathogenic	0.928
BRCA1	P38398-1.2	P871G	Pathogenic	0.854
BRCA1	P38398-1.2	P871H	Pathogenic	0.812
BRCA1	P38398-1.2	P871I	Pathogenic	0.875
BRCA1	P38398-1.2	P871K	Pathogenic	0.81
BRCA1	P38398-1.2	P871L	Pathogenic	0.875
BRCA1	P38398-1.2	P871M	Pathogenic	0.831
BRCA1	P38398-1.2	P871N	Pathogenic	0.723
BRCA1	P38398-1.2	P871Q	Pathogenic	0.731
BRCA1	P38398-1.2	P871R	Pathogenic	0.891
BRCA1	P38398-1.2	P871S	Pathogenic	0.7
BRCA1	P38398-1.2	P871T	Pathogenic	0.633
BRCA1	P38398-1.2	P871V	Pathogenic	0.764
BRCA1	P38398-1.2	P871W	Pathogenic	0.96
BRCA1	P38398-1.2	P871Y	Pathogenic	0.912
BRCA1	P38398-1.2	F872A	Pathogenic	0.898
BRCA1	P38398-1.2	F872C	Pathogenic	0.854
BRCA1	P38398-1.2	F872D	Pathogenic	0.879
BRCA1	P38398-1.2	F872E	Pathogenic	0.83
BRCA1	P38398-1.2	F872G	Pathogenic	0.951
BRCA1	P38398-1.2	F872H	Pathogenic	0.663
BRCA1	P38398-1.2	F872I	Pathogenic	0.552
BRCA1	P38398-1.2	F872K	Pathogenic	0.732
BRCA1	P38398-1.2	F872L	Pathogenic	0.552
BRCA1	P38398-1.2	F872M	Pathogenic	0.55
BRCA1	P38398-1.2	F872N	Pathogenic	0.867
BRCA1	P38398-1.2	F872P	Pathogenic	0.917
BRCA1	P38398-1.2	F872Q	Pathogenic	0.815
BRCA1	P38398-1.2	F872R	Pathogenic	0.785
BRCA1	P38398-1.2	F872S	Pathogenic	0.885
BRCA1	P38398-1.2	F872T	Pathogenic	0.832
BRCA1	P38398-1.2	F872V	Pathogenic	0.728
BRCA1	P38398-1.2	F872W	Pathogenic	0.553
BRCA1	P38398-1.2	F872Y	Neutral	0.267
BRCA1	P38398-1.2	S873A	Pathogenic	0.924
BRCA1	P38398-1.2	S873C	Pathogenic	0.967
BRCA1	P38398-1.2	S873D	Pathogenic	0.958
BRCA1	P38398-1.2	S873E	Pathogenic	0.971
BRCA1	P38398-1.2	S873F	Pathogenic	0.992
BRCA1	P38398-1.2	S873G	Pathogenic	0.964
BRCA1	P38398-1.2	S873H	Pathogenic	0.984
BRCA1	P38398-1.2	S873I	Pathogenic	0.99
BRCA1	P38398-1.2	S873K	Pathogenic	0.984
BRCA1	P38398-1.2	S873L	Pathogenic	0.99
BRCA1	P38398-1.2	S873M	Pathogenic	0.985
BRCA1	P38398-1.2	S873N	Pathogenic	0.946
BRCA1	P38398-1.2	S873P	Pathogenic	0.97
BRCA1	P38398-1.2	S873Q	Pathogenic	0.974
BRCA1	P38398-1.2	S873R	Pathogenic	0.991
BRCA1	P38398-1.2	S873T	Pathogenic	0.943
BRCA1	P38398-1.2	S873V	Pathogenic	0.984
BRCA1	P38398-1.2	S873W	Pathogenic	0.997
BRCA1	P38398-1.2	S873Y	Pathogenic	0.993
BRCA1	P38398-1.2	N874A	Pathogenic	0.752
BRCA1	P38398-1.2	N874C	Pathogenic	0.739
BRCA1	P38398-1.2	N874D	Neutral	0.377
BRCA1	P38398-1.2	N874E	Pathogenic	0.511
BRCA1	P38398-1.2	N874F	Pathogenic	0.841
BRCA1	P38398-1.2	N874G	Pathogenic	0.692
BRCA1	P38398-1.2	N874H	Neutral	0.466
BRCA1	P38398-1.2	N874I	Pathogenic	0.806
BRCA1	P38398-1.2	N874K	Pathogenic	0.649
BRCA1	P38398-1.2	N874L	Pathogenic	0.806
BRCA1	P38398-1.2	N874M	Pathogenic	0.744
BRCA1	P38398-1.2	N874P	Pathogenic	0.644
BRCA1	P38398-1.2	N874Q	Pathogenic	0.537
BRCA1	P38398-1.2	N874R	Pathogenic	0.711
BRCA1	P38398-1.2	N874S	Neutral	0.473
BRCA1	P38398-1.2	N874T	Neutral	0.451
BRCA1	P38398-1.2	N874V	Pathogenic	0.733
BRCA1	P38398-1.2	N874W	Pathogenic	0.934
BRCA1	P38398-1.2	N874Y	Pathogenic	0.81
BRCA1	P38398-1.2	P875A	Pathogenic	0.833
BRCA1	P38398-1.2	P875C	Pathogenic	0.872
BRCA1	P38398-1.2	P875D	Pathogenic	0.75
BRCA1	P38398-1.2	P875E	Pathogenic	0.818
BRCA1	P38398-1.2	P875F	Pathogenic	0.96
BRCA1	P38398-1.2	P875G	Pathogenic	0.916
BRCA1	P38398-1.2	P875H	Pathogenic	0.889
BRCA1	P38398-1.2	P875I	Pathogenic	0.929
BRCA1	P38398-1.2	P875K	Pathogenic	0.888
BRCA1	P38398-1.2	P875L	Pathogenic	0.929
BRCA1	P38398-1.2	P875M	Pathogenic	0.902
BRCA1	P38398-1.2	P875N	Pathogenic	0.829
BRCA1	P38398-1.2	P875Q	Pathogenic	0.835
BRCA1	P38398-1.2	P875R	Pathogenic	0.938
BRCA1	P38398-1.2	P875S	Pathogenic	0.813
BRCA1	P38398-1.2	P875T	Pathogenic	0.762
BRCA1	P38398-1.2	P875V	Pathogenic	0.857
BRCA1	P38398-1.2	P875W	Pathogenic	0.978
BRCA1	P38398-1.2	P875Y	Pathogenic	0.951
BRCA1	P38398-1.2	G876A	Neutral	0.174
BRCA1	P38398-1.2	G876C	Neutral	0.486
BRCA1	P38398-1.2	G876D	Neutral	0.338
BRCA1	P38398-1.2	G876E	Pathogenic	0.524
BRCA1	P38398-1.2	G876F	Pathogenic	0.734
BRCA1	P38398-1.2	G876H	Pathogenic	0.576
BRCA1	P38398-1.2	G876I	Pathogenic	0.757
BRCA1	P38398-1.2	G876K	Pathogenic	0.661
BRCA1	P38398-1.2	G876L	Pathogenic	0.757
BRCA1	P38398-1.2	G876M	Pathogenic	0.686
BRCA1	P38398-1.2	G876N	Neutral	0.285
BRCA1	P38398-1.2	G876P	Neutral	0.419
BRCA1	P38398-1.2	G876Q	Pathogenic	0.553
BRCA1	P38398-1.2	G876R	Pathogenic	0.722
BRCA1	P38398-1.2	G876S	Neutral	0.195
BRCA1	P38398-1.2	G876T	Neutral	0.437
BRCA1	P38398-1.2	G876V	Pathogenic	0.589
BRCA1	P38398-1.2	G876W	Pathogenic	0.78
BRCA1	P38398-1.2	G876Y	Pathogenic	0.762
BRCA1	P38398-1.2	N877A	Neutral	0.316
BRCA1	P38398-1.2	N877C	Neutral	0.3
BRCA1	P38398-1.2	N877D	Neutral	0.084
BRCA1	P38398-1.2	N877E	Neutral	0.137
BRCA1	P38398-1.2	N877F	Neutral	0.446
BRCA1	P38398-1.2	N877G	Neutral	0.255
BRCA1	P38398-1.2	N877H	Neutral	0.117
BRCA1	P38398-1.2	N877I	Neutral	0.387
BRCA1	P38398-1.2	N877K	Neutral	0.219
BRCA1	P38398-1.2	N877L	Neutral	0.387
BRCA1	P38398-1.2	N877M	Neutral	0.307
BRCA1	P38398-1.2	N877P	Neutral	0.215
BRCA1	P38398-1.2	N877Q	Neutral	0.15
BRCA1	P38398-1.2	N877R	Neutral	0.273
BRCA1	P38398-1.2	N877S	Neutral	0.12
BRCA1	P38398-1.2	N877T	Neutral	0.111
BRCA1	P38398-1.2	N877V	Neutral	0.295
BRCA1	P38398-1.2	N877W	Pathogenic	0.681
BRCA1	P38398-1.2	N877Y	Neutral	0.394
BRCA1	P38398-1.2	A878C	Neutral	0.017
BRCA1	P38398-1.2	A878D	Neutral	0.038
BRCA1	P38398-1.2	A878E	Neutral	0.039
BRCA1	P38398-1.2	A878F	Neutral	0.094
BRCA1	P38398-1.2	A878G	Neutral	0.017
BRCA1	P38398-1.2	A878H	Neutral	0.068
BRCA1	P38398-1.2	A878I	Neutral	0.054
BRCA1	P38398-1.2	A878K	Neutral	0.068
BRCA1	P38398-1.2	A878L	Neutral	0.054
BRCA1	P38398-1.2	A878M	Neutral	0.054
BRCA1	P38398-1.2	A878N	Neutral	0.042
BRCA1	P38398-1.2	A878P	Neutral	0.026
BRCA1	P38398-1.2	A878Q	Neutral	0.044
BRCA1	P38398-1.2	A878R	Neutral	0.088
BRCA1	P38398-1.2	A878S	Neutral	0.009
BRCA1	P38398-1.2	A878T	Neutral	0.02
BRCA1	P38398-1.2	A878V	Neutral	0.025
BRCA1	P38398-1.2	A878W	Neutral	0.217
BRCA1	P38398-1.2	A878Y	Neutral	0.108
BRCA1	P38398-1.2	E879A	Pathogenic	0.691
BRCA1	P38398-1.2	E879C	Pathogenic	0.812
BRCA1	P38398-1.2	E879D	Neutral	0.309
BRCA1	P38398-1.2	E879F	Pathogenic	0.759
BRCA1	P38398-1.2	E879G	Pathogenic	0.831
BRCA1	P38398-1.2	E879H	Neutral	0.428
BRCA1	P38398-1.2	E879I	Pathogenic	0.712
BRCA1	P38398-1.2	E879K	Neutral	0.433
BRCA1	P38398-1.2	E879L	Pathogenic	0.712
BRCA1	P38398-1.2	E879M	Pathogenic	0.634
BRCA1	P38398-1.2	E879N	Neutral	0.453
BRCA1	P38398-1.2	E879P	Pathogenic	0.571
BRCA1	P38398-1.2	E879Q	Neutral	0.25
BRCA1	P38398-1.2	E879R	Pathogenic	0.595
BRCA1	P38398-1.2	E879S	Pathogenic	0.577
BRCA1	P38398-1.2	E879T	Pathogenic	0.556
BRCA1	P38398-1.2	E879V	Pathogenic	0.576
BRCA1	P38398-1.2	E879W	Pathogenic	0.853
BRCA1	P38398-1.2	E879Y	Pathogenic	0.718
BRCA1	P38398-1.2	E880A	Neutral	0.213
BRCA1	P38398-1.2	E880C	Neutral	0.343
BRCA1	P38398-1.2	E880D	Neutral	0.051
BRCA1	P38398-1.2	E880F	Neutral	0.277
BRCA1	P38398-1.2	E880G	Neutral	0.374
BRCA1	P38398-1.2	E880H	Neutral	0.083
BRCA1	P38398-1.2	E880I	Neutral	0.23
BRCA1	P38398-1.2	E880K	Neutral	0.085
BRCA1	P38398-1.2	E880L	Neutral	0.231
BRCA1	P38398-1.2	E880M	Neutral	0.174
BRCA1	P38398-1.2	E880N	Neutral	0.091
BRCA1	P38398-1.2	E880P	Neutral	0.139
BRCA1	P38398-1.2	E880Q	Neutral	0.039
BRCA1	P38398-1.2	E880R	Neutral	0.151
BRCA1	P38398-1.2	E880S	Neutral	0.142
BRCA1	P38398-1.2	E880T	Neutral	0.132
BRCA1	P38398-1.2	E880V	Neutral	0.141
BRCA1	P38398-1.2	E880W	Neutral	0.414
BRCA1	P38398-1.2	E880Y	Neutral	0.236
BRCA1	P38398-1.2	E881A	Neutral	0.116
BRCA1	P38398-1.2	E881C	Neutral	0.202
BRCA1	P38398-1.2	E881D	Neutral	0.026
BRCA1	P38398-1.2	E881F	Neutral	0.157
BRCA1	P38398-1.2	E881G	Neutral	0.225
BRCA1	P38398-1.2	E881H	Neutral	0.042
BRCA1	P38398-1.2	E881I	Neutral	0.127
BRCA1	P38398-1.2	E881K	Neutral	0.043
BRCA1	P38398-1.2	E881L	Neutral	0.127
BRCA1	P38398-1.2	E881M	Neutral	0.093
BRCA1	P38398-1.2	E881N	Neutral	0.047
BRCA1	P38398-1.2	E881P	Neutral	0.073
BRCA1	P38398-1.2	E881Q	Neutral	0.019
BRCA1	P38398-1.2	E881R	Neutral	0.08
BRCA1	P38398-1.2	E881S	Neutral	0.075
BRCA1	P38398-1.2	E881T	Neutral	0.069
BRCA1	P38398-1.2	E881V	Neutral	0.074
BRCA1	P38398-1.2	E881W	Neutral	0.255
BRCA1	P38398-1.2	E881Y	Neutral	0.13
BRCA1	P38398-1.2	C882A	Neutral	0.164
BRCA1	P38398-1.2	C882D	Neutral	0.295
BRCA1	P38398-1.2	C882E	Neutral	0.474
BRCA1	P38398-1.2	C882F	Neutral	0.44
BRCA1	P38398-1.2	C882G	Neutral	0.469
BRCA1	P38398-1.2	C882H	Neutral	0.437
BRCA1	P38398-1.2	C882I	Neutral	0.3
BRCA1	P38398-1.2	C882K	Pathogenic	0.525
BRCA1	P38398-1.2	C882L	Neutral	0.3
BRCA1	P38398-1.2	C882M	Neutral	0.302
BRCA1	P38398-1.2	C882N	Neutral	0.319
BRCA1	P38398-1.2	C882P	Neutral	0.296
BRCA1	P38398-1.2	C882Q	Neutral	0.413
BRCA1	P38398-1.2	C882R	Pathogenic	0.596
BRCA1	P38398-1.2	C882S	Neutral	0.197
BRCA1	P38398-1.2	C882T	Neutral	0.177
BRCA1	P38398-1.2	C882V	Neutral	0.221
BRCA1	P38398-1.2	C882W	Pathogenic	0.592
BRCA1	P38398-1.2	C882Y	Neutral	0.477
BRCA1	P38398-1.2	A883C	Neutral	0.076
BRCA1	P38398-1.2	A883D	Neutral	0.159
BRCA1	P38398-1.2	A883E	Neutral	0.164
BRCA1	P38398-1.2	A883F	Neutral	0.332
BRCA1	P38398-1.2	A883G	Neutral	0.076
BRCA1	P38398-1.2	A883H	Neutral	0.259
BRCA1	P38398-1.2	A883I	Neutral	0.213
BRCA1	P38398-1.2	A883K	Neutral	0.258
BRCA1	P38398-1.2	A883L	Neutral	0.213
BRCA1	P38398-1.2	A883M	Neutral	0.215
BRCA1	P38398-1.2	A883N	Neutral	0.175
BRCA1	P38398-1.2	A883P	Neutral	0.115
BRCA1	P38398-1.2	A883Q	Neutral	0.181
BRCA1	P38398-1.2	A883R	Neutral	0.317
BRCA1	P38398-1.2	A883S	Neutral	0.041
BRCA1	P38398-1.2	A883T	Neutral	0.089
BRCA1	P38398-1.2	A883V	Neutral	0.111
BRCA1	P38398-1.2	A883W	Pathogenic	0.569
BRCA1	P38398-1.2	A883Y	Neutral	0.366
BRCA1	P38398-1.2	T884A	Neutral	0.031
BRCA1	P38398-1.2	T884C	Neutral	0.029
BRCA1	P38398-1.2	T884D	Neutral	0.026
BRCA1	P38398-1.2	T884E	Neutral	0.035
BRCA1	P38398-1.2	T884F	Neutral	0.085
BRCA1	P38398-1.2	T884G	Neutral	0.092
BRCA1	P38398-1.2	T884H	Neutral	0.061
BRCA1	P38398-1.2	T884I	Neutral	0.048
BRCA1	P38398-1.2	T884K	Neutral	0.061
BRCA1	P38398-1.2	T884L	Neutral	0.048
BRCA1	P38398-1.2	T884M	Neutral	0.048
BRCA1	P38398-1.2	T884N	Neutral	0.019
BRCA1	P38398-1.2	T884P	Neutral	0.027
BRCA1	P38398-1.2	T884Q	Neutral	0.04
BRCA1	P38398-1.2	T884R	Neutral	0.079
BRCA1	P38398-1.2	T884S	Neutral	0.019
BRCA1	P38398-1.2	T884V	Neutral	0.023
BRCA1	P38398-1.2	T884W	Neutral	0.146
BRCA1	P38398-1.2	T884Y	Neutral	0.097
BRCA1	P38398-1.2	F885A	Neutral	0.047
BRCA1	P38398-1.2	F885C	Neutral	0.032
BRCA1	P38398-1.2	F885D	Neutral	0.039
BRCA1	P38398-1.2	F885E	Neutral	0.027
BRCA1	P38398-1.2	F885G	Neutral	0.097
BRCA1	P38398-1.2	F885H	Neutral	0.011
BRCA1	P38398-1.2	F885I	Neutral	0.007
BRCA1	P38398-1.2	F885K	Neutral	0.015
BRCA1	P38398-1.2	F885L	Neutral	0.007
BRCA1	P38398-1.2	F885M	Neutral	0.007
BRCA1	P38398-1.2	F885N	Neutral	0.035
BRCA1	P38398-1.2	F885P	Neutral	0.058
BRCA1	P38398-1.2	F885Q	Neutral	0.024
BRCA1	P38398-1.2	F885R	Neutral	0.02
BRCA1	P38398-1.2	F885S	Neutral	0.041
BRCA1	P38398-1.2	F885T	Neutral	0.027
BRCA1	P38398-1.2	F885V	Neutral	0.015
BRCA1	P38398-1.2	F885W	Neutral	0.007
BRCA1	P38398-1.2	F885Y	Neutral	0.002
BRCA1	P38398-1.2	S886A	Neutral	0.0
BRCA1	P38398-1.2	S886C	Neutral	0.001
BRCA1	P38398-1.2	S886D	Neutral	0.001
BRCA1	P38398-1.2	S886E	Neutral	0.001
BRCA1	P38398-1.2	S886F	Neutral	0.003
BRCA1	P38398-1.2	S886G	Neutral	0.001
BRCA1	P38398-1.2	S886H	Neutral	0.002
BRCA1	P38398-1.2	S886I	Neutral	0.003
BRCA1	P38398-1.2	S886K	Neutral	0.002
BRCA1	P38398-1.2	S886L	Neutral	0.003
BRCA1	P38398-1.2	S886M	Neutral	0.002
BRCA1	P38398-1.2	S886N	Neutral	0.0
BRCA1	P38398-1.2	S886P	Neutral	0.001
BRCA1	P38398-1.2	S886Q	Neutral	0.001
BRCA1	P38398-1.2	S886R	Neutral	0.003
BRCA1	P38398-1.2	S886T	Neutral	0.0
BRCA1	P38398-1.2	S886V	Neutral	0.002
BRCA1	P38398-1.2	S886W	Neutral	0.009
BRCA1	P38398-1.2	S886Y	Neutral	0.004
BRCA1	P38398-1.2	A887C	Neutral	0.241
BRCA1	P38398-1.2	A887D	Neutral	0.422
BRCA1	P38398-1.2	A887E	Neutral	0.432
BRCA1	P38398-1.2	A887F	Pathogenic	0.658
BRCA1	P38398-1.2	A887G	Neutral	0.243
BRCA1	P38398-1.2	A887H	Pathogenic	0.575
BRCA1	P38398-1.2	A887I	Pathogenic	0.512
BRCA1	P38398-1.2	A887K	Pathogenic	0.573
BRCA1	P38398-1.2	A887L	Pathogenic	0.512
BRCA1	P38398-1.2	A887M	Pathogenic	0.515
BRCA1	P38398-1.2	A887N	Neutral	0.45
BRCA1	P38398-1.2	A887P	Neutral	0.335
BRCA1	P38398-1.2	A887Q	Neutral	0.461
BRCA1	P38398-1.2	A887R	Pathogenic	0.642
BRCA1	P38398-1.2	A887S	Neutral	0.143
BRCA1	P38398-1.2	A887T	Neutral	0.273
BRCA1	P38398-1.2	A887V	Neutral	0.326
BRCA1	P38398-1.2	A887W	Pathogenic	0.837
BRCA1	P38398-1.2	A887Y	Pathogenic	0.691
BRCA1	P38398-1.2	H888A	Neutral	0.172
BRCA1	P38398-1.2	H888C	Neutral	0.162
BRCA1	P38398-1.2	H888D	Neutral	0.077
BRCA1	P38398-1.2	H888E	Neutral	0.038
BRCA1	P38398-1.2	H888F	Neutral	0.062
BRCA1	P38398-1.2	H888G	Neutral	0.241
BRCA1	P38398-1.2	H888I	Neutral	0.096
BRCA1	P38398-1.2	H888K	Neutral	0.062
BRCA1	P38398-1.2	H888L	Neutral	0.097
BRCA1	P38398-1.2	H888M	Neutral	0.07
BRCA1	P38398-1.2	H888N	Neutral	0.035
BRCA1	P38398-1.2	H888P	Neutral	0.11
BRCA1	P38398-1.2	H888Q	Neutral	0.034
BRCA1	P38398-1.2	H888R	Neutral	0.058
BRCA1	P38398-1.2	H888S	Neutral	0.112
BRCA1	P38398-1.2	H888T	Neutral	0.104
BRCA1	P38398-1.2	H888V	Neutral	0.112
BRCA1	P38398-1.2	H888W	Neutral	0.149
BRCA1	P38398-1.2	H888Y	Neutral	0.025
BRCA1	P38398-1.2	S889A	Pathogenic	0.6
BRCA1	P38398-1.2	S889C	Pathogenic	0.782
BRCA1	P38398-1.2	S889D	Pathogenic	0.737
BRCA1	P38398-1.2	S889E	Pathogenic	0.807
BRCA1	P38398-1.2	S889F	Pathogenic	0.938
BRCA1	P38398-1.2	S889G	Pathogenic	0.768
BRCA1	P38398-1.2	S889H	Pathogenic	0.881
BRCA1	P38398-1.2	S889I	Pathogenic	0.922
BRCA1	P38398-1.2	S889K	Pathogenic	0.881
BRCA1	P38398-1.2	S889L	Pathogenic	0.922
BRCA1	P38398-1.2	S889M	Pathogenic	0.892
BRCA1	P38398-1.2	S889N	Pathogenic	0.685
BRCA1	P38398-1.2	S889P	Pathogenic	0.797
BRCA1	P38398-1.2	S889Q	Pathogenic	0.825
BRCA1	P38398-1.2	S889R	Pathogenic	0.934
BRCA1	P38398-1.2	S889T	Pathogenic	0.672
BRCA1	P38398-1.2	S889V	Pathogenic	0.887
BRCA1	P38398-1.2	S889W	Pathogenic	0.976
BRCA1	P38398-1.2	S889Y	Pathogenic	0.946
BRCA1	P38398-1.2	G890A	Neutral	0.0
BRCA1	P38398-1.2	G890C	Neutral	0.001
BRCA1	P38398-1.2	G890D	Neutral	0.0
BRCA1	P38398-1.2	G890E	Neutral	0.001
BRCA1	P38398-1.2	G890F	Neutral	0.003
BRCA1	P38398-1.2	G890H	Neutral	0.001
BRCA1	P38398-1.2	G890I	Neutral	0.003
BRCA1	P38398-1.2	G890K	Neutral	0.002
BRCA1	P38398-1.2	G890L	Neutral	0.003
BRCA1	P38398-1.2	G890M	Neutral	0.002
BRCA1	P38398-1.2	G890N	Neutral	0.0
BRCA1	P38398-1.2	G890P	Neutral	0.001
BRCA1	P38398-1.2	G890Q	Neutral	0.001
BRCA1	P38398-1.2	G890R	Neutral	0.002
BRCA1	P38398-1.2	G890S	Neutral	0.0
BRCA1	P38398-1.2	G890T	Neutral	0.001
BRCA1	P38398-1.2	G890V	Neutral	0.001
BRCA1	P38398-1.2	G890W	Neutral	0.003
BRCA1	P38398-1.2	G890Y	Neutral	0.003
BRCA1	P38398-1.2	S891A	Neutral	0.02
BRCA1	P38398-1.2	S891C	Neutral	0.046
BRCA1	P38398-1.2	S891D	Neutral	0.037
BRCA1	P38398-1.2	S891E	Neutral	0.054
BRCA1	P38398-1.2	S891F	Neutral	0.17
BRCA1	P38398-1.2	S891G	Neutral	0.043
BRCA1	P38398-1.2	S891H	Neutral	0.092
BRCA1	P38398-1.2	S891I	Neutral	0.138
BRCA1	P38398-1.2	S891K	Neutral	0.091
BRCA1	P38398-1.2	S891L	Neutral	0.139
BRCA1	P38398-1.2	S891M	Neutral	0.101
BRCA1	P38398-1.2	S891N	Neutral	0.029
BRCA1	P38398-1.2	S891P	Neutral	0.051
BRCA1	P38398-1.2	S891Q	Neutral	0.06
BRCA1	P38398-1.2	S891R	Neutral	0.162
BRCA1	P38398-1.2	S891T	Neutral	0.027
BRCA1	P38398-1.2	S891V	Neutral	0.096
BRCA1	P38398-1.2	S891W	Neutral	0.353
BRCA1	P38398-1.2	S891Y	Neutral	0.192
BRCA1	P38398-1.2	L892A	Pathogenic	0.594
BRCA1	P38398-1.2	L892C	Neutral	0.493
BRCA1	P38398-1.2	L892D	Pathogenic	0.715
BRCA1	P38398-1.2	L892E	Pathogenic	0.54
BRCA1	P38398-1.2	L892F	Neutral	0.273
BRCA1	P38398-1.2	L892G	Pathogenic	0.869
BRCA1	P38398-1.2	L892H	Neutral	0.494
BRCA1	P38398-1.2	L892I	Neutral	0.124
BRCA1	P38398-1.2	L892K	Neutral	0.426
BRCA1	P38398-1.2	L892M	Neutral	0.124
BRCA1	P38398-1.2	L892N	Pathogenic	0.61
BRCA1	P38398-1.2	L892P	Pathogenic	0.647
BRCA1	P38398-1.2	L892Q	Neutral	0.424
BRCA1	P38398-1.2	L892R	Neutral	0.497
BRCA1	P38398-1.2	L892S	Pathogenic	0.647
BRCA1	P38398-1.2	L892T	Neutral	0.451
BRCA1	P38398-1.2	L892V	Neutral	0.236
BRCA1	P38398-1.2	L892W	Pathogenic	0.59
BRCA1	P38398-1.2	L892Y	Neutral	0.379
BRCA1	P38398-1.2	K893A	Neutral	0.03
BRCA1	P38398-1.2	K893C	Neutral	0.04
BRCA1	P38398-1.2	K893D	Neutral	0.018
BRCA1	P38398-1.2	K893E	Neutral	0.006
BRCA1	P38398-1.2	K893F	Neutral	0.013
BRCA1	P38398-1.2	K893G	Neutral	0.064
BRCA1	P38398-1.2	K893H	Neutral	0.01
BRCA1	P38398-1.2	K893I	Neutral	0.017
BRCA1	P38398-1.2	K893L	Neutral	0.012
BRCA1	P38398-1.2	K893M	Neutral	0.008
BRCA1	P38398-1.2	K893N	Neutral	0.011
BRCA1	P38398-1.2	K893P	Neutral	0.018
BRCA1	P38398-1.2	K893Q	Neutral	0.005
BRCA1	P38398-1.2	K893R	Neutral	0.003
BRCA1	P38398-1.2	K893S	Neutral	0.018
BRCA1	P38398-1.2	K893T	Neutral	0.017
BRCA1	P38398-1.2	K893V	Neutral	0.018
BRCA1	P38398-1.2	K893W	Neutral	0.025
BRCA1	P38398-1.2	K893Y	Neutral	0.011
BRCA1	P38398-1.2	K894A	Neutral	0.297
BRCA1	P38398-1.2	K894C	Neutral	0.362
BRCA1	P38398-1.2	K894D	Neutral	0.202
BRCA1	P38398-1.2	K894E	Neutral	0.076
BRCA1	P38398-1.2	K894F	Neutral	0.158
BRCA1	P38398-1.2	K894G	Neutral	0.483
BRCA1	P38398-1.2	K894H	Neutral	0.12
BRCA1	P38398-1.2	K894I	Neutral	0.193
BRCA1	P38398-1.2	K894L	Neutral	0.143
BRCA1	P38398-1.2	K894M	Neutral	0.105
BRCA1	P38398-1.2	K894N	Neutral	0.136
BRCA1	P38398-1.2	K894P	Neutral	0.201
BRCA1	P38398-1.2	K894Q	Neutral	0.068
BRCA1	P38398-1.2	K894R	Neutral	0.041
BRCA1	P38398-1.2	K894S	Neutral	0.206
BRCA1	P38398-1.2	K894T	Neutral	0.192
BRCA1	P38398-1.2	K894V	Neutral	0.204
BRCA1	P38398-1.2	K894W	Neutral	0.257
BRCA1	P38398-1.2	K894Y	Neutral	0.132
BRCA1	P38398-1.2	Q895A	Neutral	0.371
BRCA1	P38398-1.2	Q895C	Neutral	0.441
BRCA1	P38398-1.2	Q895D	Neutral	0.194
BRCA1	P38398-1.2	Q895E	Neutral	0.072
BRCA1	P38398-1.2	Q895F	Neutral	0.4
BRCA1	P38398-1.2	Q895G	Pathogenic	0.565
BRCA1	P38398-1.2	Q895H	Neutral	0.136
BRCA1	P38398-1.2	Q895I	Neutral	0.343
BRCA1	P38398-1.2	Q895K	Neutral	0.137
BRCA1	P38398-1.2	Q895L	Neutral	0.266
BRCA1	P38398-1.2	Q895M	Neutral	0.15
BRCA1	P38398-1.2	Q895N	Neutral	0.177
BRCA1	P38398-1.2	Q895P	Neutral	0.26
BRCA1	P38398-1.2	Q895R	Neutral	0.175
BRCA1	P38398-1.2	Q895S	Neutral	0.265
BRCA1	P38398-1.2	Q895T	Neutral	0.249
BRCA1	P38398-1.2	Q895V	Neutral	0.264
BRCA1	P38398-1.2	Q895W	Neutral	0.461
BRCA1	P38398-1.2	Q895Y	Neutral	0.272
BRCA1	P38398-1.2	S896A	Neutral	0.373
BRCA1	P38398-1.2	S896C	Pathogenic	0.587
BRCA1	P38398-1.2	S896D	Pathogenic	0.526
BRCA1	P38398-1.2	S896E	Pathogenic	0.624
BRCA1	P38398-1.2	S896F	Pathogenic	0.857
BRCA1	P38398-1.2	S896G	Pathogenic	0.568
BRCA1	P38398-1.2	S896H	Pathogenic	0.746
BRCA1	P38398-1.2	S896I	Pathogenic	0.824
BRCA1	P38398-1.2	S896K	Pathogenic	0.746
BRCA1	P38398-1.2	S896L	Pathogenic	0.824
BRCA1	P38398-1.2	S896M	Pathogenic	0.767
BRCA1	P38398-1.2	S896N	Neutral	0.464
BRCA1	P38398-1.2	S896P	Pathogenic	0.61
BRCA1	P38398-1.2	S896Q	Pathogenic	0.652
BRCA1	P38398-1.2	S896R	Pathogenic	0.849
BRCA1	P38398-1.2	S896T	Neutral	0.448
BRCA1	P38398-1.2	S896V	Pathogenic	0.756
BRCA1	P38398-1.2	S896W	Pathogenic	0.941
BRCA1	P38398-1.2	S896Y	Pathogenic	0.874
BRCA1	P38398-1.2	P897A	Pathogenic	0.84
BRCA1	P38398-1.2	P897C	Pathogenic	0.877
BRCA1	P38398-1.2	P897D	Pathogenic	0.759
BRCA1	P38398-1.2	P897E	Pathogenic	0.825
BRCA1	P38398-1.2	P897F	Pathogenic	0.962
BRCA1	P38398-1.2	P897G	Pathogenic	0.92
BRCA1	P38398-1.2	P897H	Pathogenic	0.894
BRCA1	P38398-1.2	P897I	Pathogenic	0.932
BRCA1	P38398-1.2	P897K	Pathogenic	0.893
BRCA1	P38398-1.2	P897L	Pathogenic	0.932
BRCA1	P38398-1.2	P897M	Pathogenic	0.906
BRCA1	P38398-1.2	P897N	Pathogenic	0.835
BRCA1	P38398-1.2	P897Q	Pathogenic	0.841
BRCA1	P38398-1.2	P897R	Pathogenic	0.941
BRCA1	P38398-1.2	P897S	Pathogenic	0.82
BRCA1	P38398-1.2	P897T	Pathogenic	0.77
BRCA1	P38398-1.2	P897V	Pathogenic	0.863
BRCA1	P38398-1.2	P897W	Pathogenic	0.979
BRCA1	P38398-1.2	P897Y	Pathogenic	0.953
BRCA1	P38398-1.2	K898A	Neutral	0.085
BRCA1	P38398-1.2	K898C	Neutral	0.111
BRCA1	P38398-1.2	K898D	Neutral	0.053
BRCA1	P38398-1.2	K898E	Neutral	0.018
BRCA1	P38398-1.2	K898F	Neutral	0.04
BRCA1	P38398-1.2	K898G	Neutral	0.17
BRCA1	P38398-1.2	K898H	Neutral	0.029
BRCA1	P38398-1.2	K898I	Neutral	0.05
BRCA1	P38398-1.2	K898L	Neutral	0.035
BRCA1	P38398-1.2	K898M	Neutral	0.025
BRCA1	P38398-1.2	K898N	Neutral	0.033
BRCA1	P38398-1.2	K898P	Neutral	0.052
BRCA1	P38398-1.2	K898Q	Neutral	0.016
BRCA1	P38398-1.2	K898R	Neutral	0.009
BRCA1	P38398-1.2	K898S	Neutral	0.054
BRCA1	P38398-1.2	K898T	Neutral	0.05
BRCA1	P38398-1.2	K898V	Neutral	0.054
BRCA1	P38398-1.2	K898W	Neutral	0.071
BRCA1	P38398-1.2	K898Y	Neutral	0.032
BRCA1	P38398-1.2	V899A	Neutral	0.454
BRCA1	P38398-1.2	V899C	Neutral	0.443
BRCA1	P38398-1.2	V899D	Pathogenic	0.588
BRCA1	P38398-1.2	V899E	Neutral	0.443
BRCA1	P38398-1.2	V899F	Pathogenic	0.502
BRCA1	P38398-1.2	V899G	Pathogenic	0.79
BRCA1	P38398-1.2	V899H	Pathogenic	0.586
BRCA1	P38398-1.2	V899I	Neutral	0.155
BRCA1	P38398-1.2	V899K	Pathogenic	0.584
BRCA1	P38398-1.2	V899L	Neutral	0.276
BRCA1	P38398-1.2	V899M	Neutral	0.278
BRCA1	P38398-1.2	V899N	Pathogenic	0.561
BRCA1	P38398-1.2	V899P	Pathogenic	0.51
BRCA1	P38398-1.2	V899Q	Neutral	0.472
BRCA1	P38398-1.2	V899R	Pathogenic	0.73
BRCA1	P38398-1.2	V899S	Pathogenic	0.6
BRCA1	P38398-1.2	V899T	Neutral	0.318
BRCA1	P38398-1.2	V899W	Pathogenic	0.794
BRCA1	P38398-1.2	V899Y	Pathogenic	0.537
BRCA1	P38398-1.2	T900A	Neutral	0.185
BRCA1	P38398-1.2	T900C	Neutral	0.174
BRCA1	P38398-1.2	T900D	Neutral	0.158
BRCA1	P38398-1.2	T900E	Neutral	0.204
BRCA1	P38398-1.2	T900F	Neutral	0.394
BRCA1	P38398-1.2	T900G	Neutral	0.416
BRCA1	P38398-1.2	T900H	Neutral	0.314
BRCA1	P38398-1.2	T900I	Neutral	0.262
BRCA1	P38398-1.2	T900K	Neutral	0.313
BRCA1	P38398-1.2	T900L	Neutral	0.262
BRCA1	P38398-1.2	T900M	Neutral	0.264
BRCA1	P38398-1.2	T900N	Neutral	0.118
BRCA1	P38398-1.2	T900P	Neutral	0.163
BRCA1	P38398-1.2	T900Q	Neutral	0.225
BRCA1	P38398-1.2	T900R	Neutral	0.378
BRCA1	P38398-1.2	T900S	Neutral	0.121
BRCA1	P38398-1.2	T900V	Neutral	0.14
BRCA1	P38398-1.2	T900W	Pathogenic	0.546
BRCA1	P38398-1.2	T900Y	Neutral	0.43
BRCA1	P38398-1.2	F901A	Neutral	0.029
BRCA1	P38398-1.2	F901C	Neutral	0.02
BRCA1	P38398-1.2	F901D	Neutral	0.024
BRCA1	P38398-1.2	F901E	Neutral	0.016
BRCA1	P38398-1.2	F901G	Neutral	0.062
BRCA1	P38398-1.2	F901H	Neutral	0.007
BRCA1	P38398-1.2	F901I	Neutral	0.004
BRCA1	P38398-1.2	F901K	Neutral	0.009
BRCA1	P38398-1.2	F901L	Neutral	0.004
BRCA1	P38398-1.2	F901M	Neutral	0.004
BRCA1	P38398-1.2	F901N	Neutral	0.022
BRCA1	P38398-1.2	F901P	Neutral	0.036
BRCA1	P38398-1.2	F901Q	Neutral	0.015
BRCA1	P38398-1.2	F901R	Neutral	0.012
BRCA1	P38398-1.2	F901S	Neutral	0.026
BRCA1	P38398-1.2	F901T	Neutral	0.017
BRCA1	P38398-1.2	F901V	Neutral	0.009
BRCA1	P38398-1.2	F901W	Neutral	0.004
BRCA1	P38398-1.2	F901Y	Neutral	0.001
BRCA1	P38398-1.2	E902A	Neutral	0.192
BRCA1	P38398-1.2	E902C	Neutral	0.314
BRCA1	P38398-1.2	E902D	Neutral	0.045
BRCA1	P38398-1.2	E902F	Neutral	0.251
BRCA1	P38398-1.2	E902G	Neutral	0.344
BRCA1	P38398-1.2	E902H	Neutral	0.074
BRCA1	P38398-1.2	E902I	Neutral	0.208
BRCA1	P38398-1.2	E902K	Neutral	0.075
BRCA1	P38398-1.2	E902L	Neutral	0.208
BRCA1	P38398-1.2	E902M	Neutral	0.156
BRCA1	P38398-1.2	E902N	Neutral	0.081
BRCA1	P38398-1.2	E902P	Neutral	0.124
BRCA1	P38398-1.2	E902Q	Neutral	0.034
BRCA1	P38398-1.2	E902R	Neutral	0.135
BRCA1	P38398-1.2	E902S	Neutral	0.127
BRCA1	P38398-1.2	E902T	Neutral	0.118
BRCA1	P38398-1.2	E902V	Neutral	0.126
BRCA1	P38398-1.2	E902W	Neutral	0.382
BRCA1	P38398-1.2	E902Y	Neutral	0.213
BRCA1	P38398-1.2	C903A	Neutral	0.141
BRCA1	P38398-1.2	C903D	Neutral	0.261
BRCA1	P38398-1.2	C903E	Neutral	0.431
BRCA1	P38398-1.2	C903F	Neutral	0.399
BRCA1	P38398-1.2	C903G	Neutral	0.427
BRCA1	P38398-1.2	C903H	Neutral	0.395
BRCA1	P38398-1.2	C903I	Neutral	0.265
BRCA1	P38398-1.2	C903K	Neutral	0.483
BRCA1	P38398-1.2	C903L	Neutral	0.265
BRCA1	P38398-1.2	C903M	Neutral	0.267
BRCA1	P38398-1.2	C903N	Neutral	0.283
BRCA1	P38398-1.2	C903P	Neutral	0.262
BRCA1	P38398-1.2	C903Q	Neutral	0.372
BRCA1	P38398-1.2	C903R	Pathogenic	0.554
BRCA1	P38398-1.2	C903S	Neutral	0.171
BRCA1	P38398-1.2	C903T	Neutral	0.154
BRCA1	P38398-1.2	C903V	Neutral	0.193
BRCA1	P38398-1.2	C903W	Pathogenic	0.55
BRCA1	P38398-1.2	C903Y	Neutral	0.435
BRCA1	P38398-1.2	E904A	Neutral	0.041
BRCA1	P38398-1.2	E904C	Neutral	0.077
BRCA1	P38398-1.2	E904D	Neutral	0.009
BRCA1	P38398-1.2	E904F	Neutral	0.057
BRCA1	P38398-1.2	E904G	Neutral	0.087
BRCA1	P38398-1.2	E904H	Neutral	0.014
BRCA1	P38398-1.2	E904I	Neutral	0.045
BRCA1	P38398-1.2	E904K	Neutral	0.015
BRCA1	P38398-1.2	E904L	Neutral	0.045
BRCA1	P38398-1.2	E904M	Neutral	0.032
BRCA1	P38398-1.2	E904N	Neutral	0.016
BRCA1	P38398-1.2	E904P	Neutral	0.025
BRCA1	P38398-1.2	E904Q	Neutral	0.006
BRCA1	P38398-1.2	E904R	Neutral	0.028
BRCA1	P38398-1.2	E904S	Neutral	0.026
BRCA1	P38398-1.2	E904T	Neutral	0.024
BRCA1	P38398-1.2	E904V	Neutral	0.026
BRCA1	P38398-1.2	E904W	Neutral	0.101
BRCA1	P38398-1.2	E904Y	Neutral	0.047
BRCA1	P38398-1.2	Q905A	Pathogenic	0.617
BRCA1	P38398-1.2	Q905C	Pathogenic	0.684
BRCA1	P38398-1.2	Q905D	Neutral	0.396
BRCA1	P38398-1.2	Q905E	Neutral	0.176
BRCA1	P38398-1.2	Q905F	Pathogenic	0.645
BRCA1	P38398-1.2	Q905G	Pathogenic	0.781
BRCA1	P38398-1.2	Q905H	Neutral	0.302
BRCA1	P38398-1.2	Q905I	Pathogenic	0.588
BRCA1	P38398-1.2	Q905K	Neutral	0.303
BRCA1	P38398-1.2	Q905L	Neutral	0.498
BRCA1	P38398-1.2	Q905M	Neutral	0.326
BRCA1	P38398-1.2	Q905N	Neutral	0.371
BRCA1	P38398-1.2	Q905P	Neutral	0.49
BRCA1	P38398-1.2	Q905R	Neutral	0.367
BRCA1	P38398-1.2	Q905S	Neutral	0.497
BRCA1	P38398-1.2	Q905T	Neutral	0.475
BRCA1	P38398-1.2	Q905V	Neutral	0.495
BRCA1	P38398-1.2	Q905W	Pathogenic	0.7
BRCA1	P38398-1.2	Q905Y	Pathogenic	0.505
BRCA1	P38398-1.2	K906A	Neutral	0.126
BRCA1	P38398-1.2	K906C	Neutral	0.162
BRCA1	P38398-1.2	K906D	Neutral	0.08
BRCA1	P38398-1.2	K906E	Neutral	0.027
BRCA1	P38398-1.2	K906F	Neutral	0.06
BRCA1	P38398-1.2	K906G	Neutral	0.242
BRCA1	P38398-1.2	K906H	Neutral	0.045
BRCA1	P38398-1.2	K906I	Neutral	0.076
BRCA1	P38398-1.2	K906L	Neutral	0.054
BRCA1	P38398-1.2	K906M	Neutral	0.038
BRCA1	P38398-1.2	K906N	Neutral	0.051
BRCA1	P38398-1.2	K906P	Neutral	0.079
BRCA1	P38398-1.2	K906Q	Neutral	0.024
BRCA1	P38398-1.2	K906R	Neutral	0.014
BRCA1	P38398-1.2	K906S	Neutral	0.081
BRCA1	P38398-1.2	K906T	Neutral	0.075
BRCA1	P38398-1.2	K906V	Neutral	0.081
BRCA1	P38398-1.2	K906W	Neutral	0.106
BRCA1	P38398-1.2	K906Y	Neutral	0.049
BRCA1	P38398-1.2	E907A	Pathogenic	0.746
BRCA1	P38398-1.2	E907C	Pathogenic	0.85
BRCA1	P38398-1.2	E907D	Neutral	0.37
BRCA1	P38398-1.2	E907F	Pathogenic	0.806
BRCA1	P38398-1.2	E907G	Pathogenic	0.866
BRCA1	P38398-1.2	E907H	Neutral	0.496
BRCA1	P38398-1.2	E907I	Pathogenic	0.765
BRCA1	P38398-1.2	E907K	Pathogenic	0.502
BRCA1	P38398-1.2	E907L	Pathogenic	0.765
BRCA1	P38398-1.2	E907M	Pathogenic	0.695
BRCA1	P38398-1.2	E907N	Pathogenic	0.522
BRCA1	P38398-1.2	E907P	Pathogenic	0.636
BRCA1	P38398-1.2	E907Q	Neutral	0.305
BRCA1	P38398-1.2	E907R	Pathogenic	0.659
BRCA1	P38398-1.2	E907S	Pathogenic	0.643
BRCA1	P38398-1.2	E907T	Pathogenic	0.623
BRCA1	P38398-1.2	E907V	Pathogenic	0.641
BRCA1	P38398-1.2	E907W	Pathogenic	0.884
BRCA1	P38398-1.2	E907Y	Pathogenic	0.77
BRCA1	P38398-1.2	E908A	Neutral	0.105
BRCA1	P38398-1.2	E908C	Neutral	0.184
BRCA1	P38398-1.2	E908D	Neutral	0.023
BRCA1	P38398-1.2	E908F	Neutral	0.141
BRCA1	P38398-1.2	E908G	Neutral	0.205
BRCA1	P38398-1.2	E908H	Neutral	0.038
BRCA1	P38398-1.2	E908I	Neutral	0.114
BRCA1	P38398-1.2	E908K	Neutral	0.038
BRCA1	P38398-1.2	E908L	Neutral	0.114
BRCA1	P38398-1.2	E908M	Neutral	0.083
BRCA1	P38398-1.2	E908N	Neutral	0.042
BRCA1	P38398-1.2	E908P	Neutral	0.065
BRCA1	P38398-1.2	E908Q	Neutral	0.017
BRCA1	P38398-1.2	E908R	Neutral	0.071
BRCA1	P38398-1.2	E908S	Neutral	0.067
BRCA1	P38398-1.2	E908T	Neutral	0.062
BRCA1	P38398-1.2	E908V	Neutral	0.066
BRCA1	P38398-1.2	E908W	Neutral	0.233
BRCA1	P38398-1.2	E908Y	Neutral	0.117
BRCA1	P38398-1.2	N909A	Neutral	0.057
BRCA1	P38398-1.2	N909C	Neutral	0.053
BRCA1	P38398-1.2	N909D	Neutral	0.012
BRCA1	P38398-1.2	N909E	Neutral	0.02
BRCA1	P38398-1.2	N909F	Neutral	0.095
BRCA1	P38398-1.2	N909G	Neutral	0.043
BRCA1	P38398-1.2	N909H	Neutral	0.017
BRCA1	P38398-1.2	N909I	Neutral	0.076
BRCA1	P38398-1.2	N909K	Neutral	0.035
BRCA1	P38398-1.2	N909L	Neutral	0.076
BRCA1	P38398-1.2	N909M	Neutral	0.055
BRCA1	P38398-1.2	N909P	Neutral	0.034
BRCA1	P38398-1.2	N909Q	Neutral	0.022
BRCA1	P38398-1.2	N909R	Neutral	0.047
BRCA1	P38398-1.2	N909S	Neutral	0.017
BRCA1	P38398-1.2	N909T	Neutral	0.016
BRCA1	P38398-1.2	N909V	Neutral	0.052
BRCA1	P38398-1.2	N909W	Neutral	0.218
BRCA1	P38398-1.2	N909Y	Neutral	0.078
BRCA1	P38398-1.2	Q910A	Neutral	0.197
BRCA1	P38398-1.2	Q910C	Neutral	0.248
BRCA1	P38398-1.2	Q910D	Neutral	0.091
BRCA1	P38398-1.2	Q910E	Neutral	0.032
BRCA1	P38398-1.2	Q910F	Neutral	0.217
BRCA1	P38398-1.2	Q910G	Neutral	0.352
BRCA1	P38398-1.2	Q910H	Neutral	0.062
BRCA1	P38398-1.2	Q910I	Neutral	0.179
BRCA1	P38398-1.2	Q910K	Neutral	0.062
BRCA1	P38398-1.2	Q910L	Neutral	0.132
BRCA1	P38398-1.2	Q910M	Neutral	0.069
BRCA1	P38398-1.2	Q910N	Neutral	0.083
BRCA1	P38398-1.2	Q910P	Neutral	0.128
BRCA1	P38398-1.2	Q910R	Neutral	0.081
BRCA1	P38398-1.2	Q910S	Neutral	0.131
BRCA1	P38398-1.2	Q910T	Neutral	0.121
BRCA1	P38398-1.2	Q910V	Neutral	0.13
BRCA1	P38398-1.2	Q910W	Neutral	0.263
BRCA1	P38398-1.2	Q910Y	Neutral	0.135
BRCA1	P38398-1.2	G911A	Pathogenic	0.55
BRCA1	P38398-1.2	G911C	Pathogenic	0.846
BRCA1	P38398-1.2	G911D	Pathogenic	0.748
BRCA1	P38398-1.2	G911E	Pathogenic	0.865
BRCA1	P38398-1.2	G911F	Pathogenic	0.941
BRCA1	P38398-1.2	G911H	Pathogenic	0.887
BRCA1	P38398-1.2	G911I	Pathogenic	0.947
BRCA1	P38398-1.2	G911K	Pathogenic	0.919
BRCA1	P38398-1.2	G911L	Pathogenic	0.948
BRCA1	P38398-1.2	G911M	Pathogenic	0.927
BRCA1	P38398-1.2	G911N	Pathogenic	0.698
BRCA1	P38398-1.2	G911P	Pathogenic	0.807
BRCA1	P38398-1.2	G911Q	Pathogenic	0.878
BRCA1	P38398-1.2	G911R	Pathogenic	0.938
BRCA1	P38398-1.2	G911S	Pathogenic	0.584
BRCA1	P38398-1.2	G911T	Pathogenic	0.818
BRCA1	P38398-1.2	G911V	Pathogenic	0.893
BRCA1	P38398-1.2	G911W	Pathogenic	0.954
BRCA1	P38398-1.2	G911Y	Pathogenic	0.949
BRCA1	P38398-1.2	K912A	Neutral	0.024
BRCA1	P38398-1.2	K912C	Neutral	0.032
BRCA1	P38398-1.2	K912D	Neutral	0.015
BRCA1	P38398-1.2	K912E	Neutral	0.005
BRCA1	P38398-1.2	K912F	Neutral	0.011
BRCA1	P38398-1.2	K912G	Neutral	0.052
BRCA1	P38398-1.2	K912H	Neutral	0.008
BRCA1	P38398-1.2	K912I	Neutral	0.014
BRCA1	P38398-1.2	K912L	Neutral	0.01
BRCA1	P38398-1.2	K912M	Neutral	0.007
BRCA1	P38398-1.2	K912N	Neutral	0.009
BRCA1	P38398-1.2	K912P	Neutral	0.015
BRCA1	P38398-1.2	K912Q	Neutral	0.004
BRCA1	P38398-1.2	K912R	Neutral	0.003
BRCA1	P38398-1.2	K912S	Neutral	0.015
BRCA1	P38398-1.2	K912T	Neutral	0.014
BRCA1	P38398-1.2	K912V	Neutral	0.015
BRCA1	P38398-1.2	K912W	Neutral	0.02
BRCA1	P38398-1.2	K912Y	Neutral	0.009
BRCA1	P38398-1.2	N913A	Neutral	0.017
BRCA1	P38398-1.2	N913C	Neutral	0.016
BRCA1	P38398-1.2	N913D	Neutral	0.003
BRCA1	P38398-1.2	N913E	Neutral	0.006
BRCA1	P38398-1.2	N913F	Neutral	0.029
BRCA1	P38398-1.2	N913G	Neutral	0.013
BRCA1	P38398-1.2	N913H	Neutral	0.005
BRCA1	P38398-1.2	N913I	Neutral	0.023
BRCA1	P38398-1.2	N913K	Neutral	0.01
BRCA1	P38398-1.2	N913L	Neutral	0.023
BRCA1	P38398-1.2	N913M	Neutral	0.016
BRCA1	P38398-1.2	N913P	Neutral	0.01
BRCA1	P38398-1.2	N913Q	Neutral	0.007
BRCA1	P38398-1.2	N913R	Neutral	0.014
BRCA1	P38398-1.2	N913S	Neutral	0.005
BRCA1	P38398-1.2	N913T	Neutral	0.005
BRCA1	P38398-1.2	N913V	Neutral	0.015
BRCA1	P38398-1.2	N913W	Neutral	0.074
BRCA1	P38398-1.2	N913Y	Neutral	0.024
BRCA1	P38398-1.2	E914A	Neutral	0.473
BRCA1	P38398-1.2	E914C	Pathogenic	0.634
BRCA1	P38398-1.2	E914D	Neutral	0.152
BRCA1	P38398-1.2	E914F	Pathogenic	0.559
BRCA1	P38398-1.2	E914G	Pathogenic	0.665
BRCA1	P38398-1.2	E914H	Neutral	0.231
BRCA1	P38398-1.2	E914I	Neutral	0.498
BRCA1	P38398-1.2	E914K	Neutral	0.235
BRCA1	P38398-1.2	E914L	Neutral	0.498
BRCA1	P38398-1.2	E914M	Neutral	0.411
BRCA1	P38398-1.2	E914N	Neutral	0.25
BRCA1	P38398-1.2	E914P	Neutral	0.348
BRCA1	P38398-1.2	E914Q	Neutral	0.118
BRCA1	P38398-1.2	E914R	Neutral	0.371
BRCA1	P38398-1.2	E914S	Neutral	0.355
BRCA1	P38398-1.2	E914T	Neutral	0.335
BRCA1	P38398-1.2	E914V	Neutral	0.353
BRCA1	P38398-1.2	E914W	Pathogenic	0.7
BRCA1	P38398-1.2	E914Y	Pathogenic	0.505
BRCA1	P38398-1.2	S915A	Neutral	0.412
BRCA1	P38398-1.2	S915C	Pathogenic	0.626
BRCA1	P38398-1.2	S915D	Pathogenic	0.567
BRCA1	P38398-1.2	S915E	Pathogenic	0.662
BRCA1	P38398-1.2	S915F	Pathogenic	0.876
BRCA1	P38398-1.2	S915G	Pathogenic	0.607
BRCA1	P38398-1.2	S915H	Pathogenic	0.776
BRCA1	P38398-1.2	S915I	Pathogenic	0.847
BRCA1	P38398-1.2	S915K	Pathogenic	0.776
BRCA1	P38398-1.2	S915L	Pathogenic	0.847
BRCA1	P38398-1.2	S915M	Pathogenic	0.795
BRCA1	P38398-1.2	S915N	Pathogenic	0.505
BRCA1	P38398-1.2	S915P	Pathogenic	0.648
BRCA1	P38398-1.2	S915Q	Pathogenic	0.688
BRCA1	P38398-1.2	S915R	Pathogenic	0.869
BRCA1	P38398-1.2	S915T	Neutral	0.489
BRCA1	P38398-1.2	S915V	Pathogenic	0.785
BRCA1	P38398-1.2	S915W	Pathogenic	0.949
BRCA1	P38398-1.2	S915Y	Pathogenic	0.891
BRCA1	P38398-1.2	N916A	Neutral	0.065
BRCA1	P38398-1.2	N916C	Neutral	0.061
BRCA1	P38398-1.2	N916D	Neutral	0.014
BRCA1	P38398-1.2	N916E	Neutral	0.024
BRCA1	P38398-1.2	N916F	Neutral	0.109
BRCA1	P38398-1.2	N916G	Neutral	0.049
BRCA1	P38398-1.2	N916H	Neutral	0.02
BRCA1	P38398-1.2	N916I	Neutral	0.087
BRCA1	P38398-1.2	N916K	Neutral	0.041
BRCA1	P38398-1.2	N916L	Neutral	0.088
BRCA1	P38398-1.2	N916M	Neutral	0.063
BRCA1	P38398-1.2	N916P	Neutral	0.04
BRCA1	P38398-1.2	N916Q	Neutral	0.026
BRCA1	P38398-1.2	N916R	Neutral	0.054
BRCA1	P38398-1.2	N916S	Neutral	0.02
BRCA1	P38398-1.2	N916T	Neutral	0.019
BRCA1	P38398-1.2	N916V	Neutral	0.06
BRCA1	P38398-1.2	N916W	Neutral	0.245
BRCA1	P38398-1.2	N916Y	Neutral	0.09
BRCA1	P38398-1.2	I917A	Neutral	0.289
BRCA1	P38398-1.2	I917C	Neutral	0.212
BRCA1	P38398-1.2	I917D	Neutral	0.326
BRCA1	P38398-1.2	I917E	Neutral	0.245
BRCA1	P38398-1.2	I917F	Neutral	0.095
BRCA1	P38398-1.2	I917G	Pathogenic	0.647
BRCA1	P38398-1.2	I917H	Neutral	0.213
BRCA1	P38398-1.2	I917K	Neutral	0.228
BRCA1	P38398-1.2	I917L	Neutral	0.038
BRCA1	P38398-1.2	I917M	Neutral	0.053
BRCA1	P38398-1.2	I917N	Neutral	0.303
BRCA1	P38398-1.2	I917P	Neutral	0.337
BRCA1	P38398-1.2	I917Q	Neutral	0.227
BRCA1	P38398-1.2	I917R	Neutral	0.283
BRCA1	P38398-1.2	I917S	Neutral	0.337
BRCA1	P38398-1.2	I917T	Neutral	0.185
BRCA1	P38398-1.2	I917V	Neutral	0.04
BRCA1	P38398-1.2	I917W	Neutral	0.365
BRCA1	P38398-1.2	I917Y	Neutral	0.145
BRCA1	P38398-1.2	K918A	Neutral	0.024
BRCA1	P38398-1.2	K918C	Neutral	0.032
BRCA1	P38398-1.2	K918D	Neutral	0.014
BRCA1	P38398-1.2	K918E	Neutral	0.005
BRCA1	P38398-1.2	K918F	Neutral	0.011
BRCA1	P38398-1.2	K918G	Neutral	0.051
BRCA1	P38398-1.2	K918H	Neutral	0.008
BRCA1	P38398-1.2	K918I	Neutral	0.014
BRCA1	P38398-1.2	K918L	Neutral	0.01
BRCA1	P38398-1.2	K918M	Neutral	0.007
BRCA1	P38398-1.2	K918N	Neutral	0.009
BRCA1	P38398-1.2	K918P	Neutral	0.014
BRCA1	P38398-1.2	K918Q	Neutral	0.004
BRCA1	P38398-1.2	K918R	Neutral	0.002
BRCA1	P38398-1.2	K918S	Neutral	0.015
BRCA1	P38398-1.2	K918T	Neutral	0.013
BRCA1	P38398-1.2	K918V	Neutral	0.015
BRCA1	P38398-1.2	K918W	Neutral	0.02
BRCA1	P38398-1.2	K918Y	Neutral	0.009
BRCA1	P38398-1.2	P919A	Neutral	0.02
BRCA1	P38398-1.2	P919C	Neutral	0.026
BRCA1	P38398-1.2	P919D	Neutral	0.012
BRCA1	P38398-1.2	P919E	Neutral	0.018
BRCA1	P38398-1.2	P919F	Neutral	0.087
BRCA1	P38398-1.2	P919G	Neutral	0.042
BRCA1	P38398-1.2	P919H	Neutral	0.031
BRCA1	P38398-1.2	P919I	Neutral	0.049
BRCA1	P38398-1.2	P919K	Neutral	0.031
BRCA1	P38398-1.2	P919L	Neutral	0.049
BRCA1	P38398-1.2	P919M	Neutral	0.035
BRCA1	P38398-1.2	P919N	Neutral	0.019
BRCA1	P38398-1.2	P919Q	Neutral	0.02
BRCA1	P38398-1.2	P919R	Neutral	0.057
BRCA1	P38398-1.2	P919S	Neutral	0.017
BRCA1	P38398-1.2	P919T	Neutral	0.013
BRCA1	P38398-1.2	P919V	Neutral	0.023
BRCA1	P38398-1.2	P919W	Neutral	0.15
BRCA1	P38398-1.2	P919Y	Neutral	0.072
BRCA1	P38398-1.2	V920A	Neutral	0.126
BRCA1	P38398-1.2	V920C	Neutral	0.121
BRCA1	P38398-1.2	V920D	Neutral	0.198
BRCA1	P38398-1.2	V920E	Neutral	0.121
BRCA1	P38398-1.2	V920F	Neutral	0.149
BRCA1	P38398-1.2	V920G	Neutral	0.395
BRCA1	P38398-1.2	V920H	Neutral	0.198
BRCA1	P38398-1.2	V920I	Neutral	0.031
BRCA1	P38398-1.2	V920K	Neutral	0.196
BRCA1	P38398-1.2	V920L	Neutral	0.062
BRCA1	P38398-1.2	V920M	Neutral	0.063
BRCA1	P38398-1.2	V920N	Neutral	0.182
BRCA1	P38398-1.2	V920P	Neutral	0.153
BRCA1	P38398-1.2	V920Q	Neutral	0.135
BRCA1	P38398-1.2	V920R	Neutral	0.319
BRCA1	P38398-1.2	V920S	Neutral	0.207
BRCA1	P38398-1.2	V920T	Neutral	0.075
BRCA1	P38398-1.2	V920W	Neutral	0.401
BRCA1	P38398-1.2	V920Y	Neutral	0.168
BRCA1	P38398-1.2	Q921A	Pathogenic	0.898
BRCA1	P38398-1.2	Q921C	Pathogenic	0.922
BRCA1	P38398-1.2	Q921D	Pathogenic	0.782
BRCA1	P38398-1.2	Q921E	Pathogenic	0.537
BRCA1	P38398-1.2	Q921F	Pathogenic	0.908
BRCA1	P38398-1.2	Q921G	Pathogenic	0.951
BRCA1	P38398-1.2	Q921H	Pathogenic	0.702
BRCA1	P38398-1.2	Q921I	Pathogenic	0.886
BRCA1	P38398-1.2	Q921K	Pathogenic	0.703
BRCA1	P38398-1.2	Q921L	Pathogenic	0.844
BRCA1	P38398-1.2	Q921M	Pathogenic	0.725
BRCA1	P38398-1.2	Q921N	Pathogenic	0.763
BRCA1	P38398-1.2	Q921P	Pathogenic	0.839
BRCA1	P38398-1.2	Q921R	Pathogenic	0.76
BRCA1	P38398-1.2	Q921S	Pathogenic	0.843
BRCA1	P38398-1.2	Q921T	Pathogenic	0.831
BRCA1	P38398-1.2	Q921V	Pathogenic	0.842
BRCA1	P38398-1.2	Q921W	Pathogenic	0.927
BRCA1	P38398-1.2	Q921Y	Pathogenic	0.848
BRCA1	P38398-1.2	T922A	Neutral	0.072
BRCA1	P38398-1.2	T922C	Neutral	0.067
BRCA1	P38398-1.2	T922D	Neutral	0.06
BRCA1	P38398-1.2	T922E	Neutral	0.081
BRCA1	P38398-1.2	T922F	Neutral	0.182
BRCA1	P38398-1.2	T922G	Neutral	0.196
BRCA1	P38398-1.2	T922H	Neutral	0.136
BRCA1	P38398-1.2	T922I	Neutral	0.108
BRCA1	P38398-1.2	T922K	Neutral	0.135
BRCA1	P38398-1.2	T922L	Neutral	0.108
BRCA1	P38398-1.2	T922M	Neutral	0.109
BRCA1	P38398-1.2	T922N	Neutral	0.044
BRCA1	P38398-1.2	T922P	Neutral	0.062
BRCA1	P38398-1.2	T922Q	Neutral	0.09
BRCA1	P38398-1.2	T922R	Neutral	0.172
BRCA1	P38398-1.2	T922S	Neutral	0.045
BRCA1	P38398-1.2	T922V	Neutral	0.053
BRCA1	P38398-1.2	T922W	Neutral	0.292
BRCA1	P38398-1.2	T922Y	Neutral	0.206
BRCA1	P38398-1.2	V923A	Neutral	0.039
BRCA1	P38398-1.2	V923C	Neutral	0.038
BRCA1	P38398-1.2	V923D	Neutral	0.065
BRCA1	P38398-1.2	V923E	Neutral	0.038
BRCA1	P38398-1.2	V923F	Neutral	0.047
BRCA1	P38398-1.2	V923G	Neutral	0.156
BRCA1	P38398-1.2	V923H	Neutral	0.065
BRCA1	P38398-1.2	V923I	Neutral	0.009
BRCA1	P38398-1.2	V923K	Neutral	0.065
BRCA1	P38398-1.2	V923L	Neutral	0.018
BRCA1	P38398-1.2	V923M	Neutral	0.019
BRCA1	P38398-1.2	V923N	Neutral	0.059
BRCA1	P38398-1.2	V923P	Neutral	0.049
BRCA1	P38398-1.2	V923Q	Neutral	0.042
BRCA1	P38398-1.2	V923R	Neutral	0.117
BRCA1	P38398-1.2	V923S	Neutral	0.068
BRCA1	P38398-1.2	V923T	Neutral	0.022
BRCA1	P38398-1.2	V923W	Neutral	0.159
BRCA1	P38398-1.2	V923Y	Neutral	0.054
BRCA1	P38398-1.2	N924A	Neutral	0.001
BRCA1	P38398-1.2	N924C	Neutral	0.001
BRCA1	P38398-1.2	N924D	Neutral	0.0
BRCA1	P38398-1.2	N924E	Neutral	0.0
BRCA1	P38398-1.2	N924F	Neutral	0.002
BRCA1	P38398-1.2	N924G	Neutral	0.001
BRCA1	P38398-1.2	N924H	Neutral	0.0
BRCA1	P38398-1.2	N924I	Neutral	0.002
BRCA1	P38398-1.2	N924K	Neutral	0.001
BRCA1	P38398-1.2	N924L	Neutral	0.002
BRCA1	P38398-1.2	N924M	Neutral	0.001
BRCA1	P38398-1.2	N924P	Neutral	0.001
BRCA1	P38398-1.2	N924Q	Neutral	0.001
BRCA1	P38398-1.2	N924R	Neutral	0.001
BRCA1	P38398-1.2	N924S	Neutral	0.0
BRCA1	P38398-1.2	N924T	Neutral	0.0
BRCA1	P38398-1.2	N924V	Neutral	0.001
BRCA1	P38398-1.2	N924W	Neutral	0.006
BRCA1	P38398-1.2	N924Y	Neutral	0.002
BRCA1	P38398-1.2	I925A	Neutral	0.055
BRCA1	P38398-1.2	I925C	Neutral	0.037
BRCA1	P38398-1.2	I925D	Neutral	0.064
BRCA1	P38398-1.2	I925E	Neutral	0.044
BRCA1	P38398-1.2	I925F	Neutral	0.015
BRCA1	P38398-1.2	I925G	Neutral	0.207
BRCA1	P38398-1.2	I925H	Neutral	0.037
BRCA1	P38398-1.2	I925K	Neutral	0.04
BRCA1	P38398-1.2	I925L	Neutral	0.006
BRCA1	P38398-1.2	I925M	Neutral	0.008
BRCA1	P38398-1.2	I925N	Neutral	0.058
BRCA1	P38398-1.2	I925P	Neutral	0.067
BRCA1	P38398-1.2	I925Q	Neutral	0.04
BRCA1	P38398-1.2	I925R	Neutral	0.053
BRCA1	P38398-1.2	I925S	Neutral	0.067
BRCA1	P38398-1.2	I925T	Neutral	0.031
BRCA1	P38398-1.2	I925V	Neutral	0.006
BRCA1	P38398-1.2	I925W	Neutral	0.076
BRCA1	P38398-1.2	I925Y	Neutral	0.023
BRCA1	P38398-1.2	T926A	Neutral	0.058
BRCA1	P38398-1.2	T926C	Neutral	0.054
BRCA1	P38398-1.2	T926D	Neutral	0.048
BRCA1	P38398-1.2	T926E	Neutral	0.065
BRCA1	P38398-1.2	T926F	Neutral	0.149
BRCA1	P38398-1.2	T926G	Neutral	0.161
BRCA1	P38398-1.2	T926H	Neutral	0.11
BRCA1	P38398-1.2	T926I	Neutral	0.087
BRCA1	P38398-1.2	T926K	Neutral	0.109
BRCA1	P38398-1.2	T926L	Neutral	0.087
BRCA1	P38398-1.2	T926M	Neutral	0.088
BRCA1	P38398-1.2	T926N	Neutral	0.035
BRCA1	P38398-1.2	T926P	Neutral	0.05
BRCA1	P38398-1.2	T926Q	Neutral	0.072
BRCA1	P38398-1.2	T926R	Neutral	0.141
BRCA1	P38398-1.2	T926S	Neutral	0.036
BRCA1	P38398-1.2	T926V	Neutral	0.042
BRCA1	P38398-1.2	T926W	Neutral	0.245
BRCA1	P38398-1.2	T926Y	Neutral	0.169
BRCA1	P38398-1.2	A927C	Neutral	0.008
BRCA1	P38398-1.2	A927D	Neutral	0.019
BRCA1	P38398-1.2	A927E	Neutral	0.02
BRCA1	P38398-1.2	A927F	Neutral	0.048
BRCA1	P38398-1.2	A927G	Neutral	0.008
BRCA1	P38398-1.2	A927H	Neutral	0.035
BRCA1	P38398-1.2	A927I	Neutral	0.027
BRCA1	P38398-1.2	A927K	Neutral	0.034
BRCA1	P38398-1.2	A927L	Neutral	0.027
BRCA1	P38398-1.2	A927M	Neutral	0.027
BRCA1	P38398-1.2	A927N	Neutral	0.021
BRCA1	P38398-1.2	A927P	Neutral	0.013
BRCA1	P38398-1.2	A927Q	Neutral	0.022
BRCA1	P38398-1.2	A927R	Neutral	0.045
BRCA1	P38398-1.2	A927S	Neutral	0.004
BRCA1	P38398-1.2	A927T	Neutral	0.01
BRCA1	P38398-1.2	A927V	Neutral	0.013
BRCA1	P38398-1.2	A927W	Neutral	0.119
BRCA1	P38398-1.2	A927Y	Neutral	0.056
BRCA1	P38398-1.2	G928A	Neutral	0.063
BRCA1	P38398-1.2	G928C	Neutral	0.232
BRCA1	P38398-1.2	G928D	Neutral	0.141
BRCA1	P38398-1.2	G928E	Neutral	0.261
BRCA1	P38398-1.2	G928F	Neutral	0.469
BRCA1	P38398-1.2	G928H	Neutral	0.303
BRCA1	P38398-1.2	G928I	Neutral	0.499
BRCA1	P38398-1.2	G928K	Neutral	0.384
BRCA1	P38398-1.2	G928L	Neutral	0.5
BRCA1	P38398-1.2	G928M	Neutral	0.412
BRCA1	P38398-1.2	G928N	Neutral	0.113
BRCA1	P38398-1.2	G928P	Neutral	0.188
BRCA1	P38398-1.2	G928Q	Neutral	0.284
BRCA1	P38398-1.2	G928R	Neutral	0.454
BRCA1	P38398-1.2	G928S	Neutral	0.072
BRCA1	P38398-1.2	G928T	Neutral	0.199
BRCA1	P38398-1.2	G928V	Neutral	0.315
BRCA1	P38398-1.2	G928W	Pathogenic	0.532
BRCA1	P38398-1.2	G928Y	Pathogenic	0.507
BRCA1	P38398-1.2	F929A	Neutral	0.314
BRCA1	P38398-1.2	F929C	Neutral	0.233
BRCA1	P38398-1.2	F929D	Neutral	0.274
BRCA1	P38398-1.2	F929E	Neutral	0.203
BRCA1	P38398-1.2	F929G	Neutral	0.499
BRCA1	P38398-1.2	F929H	Neutral	0.093
BRCA1	P38398-1.2	F929I	Neutral	0.06
BRCA1	P38398-1.2	F929K	Neutral	0.124
BRCA1	P38398-1.2	F929L	Neutral	0.06
BRCA1	P38398-1.2	F929M	Neutral	0.06
BRCA1	P38398-1.2	F929N	Neutral	0.253
BRCA1	P38398-1.2	F929P	Neutral	0.364
BRCA1	P38398-1.2	F929Q	Neutral	0.186
BRCA1	P38398-1.2	F929R	Neutral	0.159
BRCA1	P38398-1.2	F929S	Neutral	0.284
BRCA1	P38398-1.2	F929T	Neutral	0.204
BRCA1	P38398-1.2	F929V	Neutral	0.122
BRCA1	P38398-1.2	F929W	Neutral	0.06
BRCA1	P38398-1.2	F929Y	Neutral	0.019
BRCA1	P38398-1.2	P930A	Neutral	0.144
BRCA1	P38398-1.2	P930C	Neutral	0.187
BRCA1	P38398-1.2	P930D	Neutral	0.092
BRCA1	P38398-1.2	P930E	Neutral	0.132
BRCA1	P38398-1.2	P930F	Neutral	0.447
BRCA1	P38398-1.2	P930G	Neutral	0.269
BRCA1	P38398-1.2	P930H	Neutral	0.213
BRCA1	P38398-1.2	P930I	Neutral	0.306
BRCA1	P38398-1.2	P930K	Neutral	0.211
BRCA1	P38398-1.2	P930L	Neutral	0.306
BRCA1	P38398-1.2	P930M	Neutral	0.236
BRCA1	P38398-1.2	P930N	Neutral	0.14
BRCA1	P38398-1.2	P930Q	Neutral	0.146
BRCA1	P38398-1.2	P930R	Neutral	0.34
BRCA1	P38398-1.2	P930S	Neutral	0.128
BRCA1	P38398-1.2	P930T	Neutral	0.097
BRCA1	P38398-1.2	P930V	Neutral	0.169
BRCA1	P38398-1.2	P930W	Pathogenic	0.599
BRCA1	P38398-1.2	P930Y	Neutral	0.395
BRCA1	P38398-1.2	V931A	Neutral	0.083
BRCA1	P38398-1.2	V931C	Neutral	0.079
BRCA1	P38398-1.2	V931D	Neutral	0.133
BRCA1	P38398-1.2	V931E	Neutral	0.079
BRCA1	P38398-1.2	V931F	Neutral	0.098
BRCA1	P38398-1.2	V931G	Neutral	0.289
BRCA1	P38398-1.2	V931H	Neutral	0.133
BRCA1	P38398-1.2	V931I	Neutral	0.02
BRCA1	P38398-1.2	V931K	Neutral	0.132
BRCA1	P38398-1.2	V931L	Neutral	0.04
BRCA1	P38398-1.2	V931M	Neutral	0.04
BRCA1	P38398-1.2	V931N	Neutral	0.122
BRCA1	P38398-1.2	V931P	Neutral	0.101
BRCA1	P38398-1.2	V931Q	Neutral	0.088
BRCA1	P38398-1.2	V931R	Neutral	0.226
BRCA1	P38398-1.2	V931S	Neutral	0.139
BRCA1	P38398-1.2	V931T	Neutral	0.048
BRCA1	P38398-1.2	V931W	Neutral	0.294
BRCA1	P38398-1.2	V931Y	Neutral	0.111
BRCA1	P38398-1.2	V932A	Neutral	0.025
BRCA1	P38398-1.2	V932C	Neutral	0.024
BRCA1	P38398-1.2	V932D	Neutral	0.042
BRCA1	P38398-1.2	V932E	Neutral	0.024
BRCA1	P38398-1.2	V932F	Neutral	0.03
BRCA1	P38398-1.2	V932G	Neutral	0.103
BRCA1	P38398-1.2	V932H	Neutral	0.041
BRCA1	P38398-1.2	V932I	Neutral	0.006
BRCA1	P38398-1.2	V932K	Neutral	0.041
BRCA1	P38398-1.2	V932L	Neutral	0.011
BRCA1	P38398-1.2	V932M	Neutral	0.012
BRCA1	P38398-1.2	V932N	Neutral	0.037
BRCA1	P38398-1.2	V932P	Neutral	0.031
BRCA1	P38398-1.2	V932Q	Neutral	0.027
BRCA1	P38398-1.2	V932R	Neutral	0.076
BRCA1	P38398-1.2	V932S	Neutral	0.044
BRCA1	P38398-1.2	V932T	Neutral	0.014
BRCA1	P38398-1.2	V932W	Neutral	0.105
BRCA1	P38398-1.2	V932Y	Neutral	0.034
BRCA1	P38398-1.2	G933A	Neutral	0.006
BRCA1	P38398-1.2	G933C	Neutral	0.026
BRCA1	P38398-1.2	G933D	Neutral	0.015
BRCA1	P38398-1.2	G933E	Neutral	0.031
BRCA1	P38398-1.2	G933F	Neutral	0.074
BRCA1	P38398-1.2	G933H	Neutral	0.038
BRCA1	P38398-1.2	G933I	Neutral	0.082
BRCA1	P38398-1.2	G933K	Neutral	0.053
BRCA1	P38398-1.2	G933L	Neutral	0.082
BRCA1	P38398-1.2	G933M	Neutral	0.059
BRCA1	P38398-1.2	G933N	Neutral	0.011
BRCA1	P38398-1.2	G933P	Neutral	0.02
BRCA1	P38398-1.2	G933Q	Neutral	0.034
BRCA1	P38398-1.2	G933R	Neutral	0.07
BRCA1	P38398-1.2	G933S	Neutral	0.007
BRCA1	P38398-1.2	G933T	Neutral	0.022
BRCA1	P38398-1.2	G933V	Neutral	0.04
BRCA1	P38398-1.2	G933W	Neutral	0.093
BRCA1	P38398-1.2	G933Y	Neutral	0.084
BRCA1	P38398-1.2	Q934A	Pathogenic	0.844
BRCA1	P38398-1.2	Q934C	Pathogenic	0.879
BRCA1	P38398-1.2	Q934D	Pathogenic	0.689
BRCA1	P38398-1.2	Q934E	Neutral	0.418
BRCA1	P38398-1.2	Q934F	Pathogenic	0.86
BRCA1	P38398-1.2	Q934G	Pathogenic	0.923
BRCA1	P38398-1.2	Q934H	Pathogenic	0.593
BRCA1	P38398-1.2	Q934I	Pathogenic	0.828
BRCA1	P38398-1.2	Q934K	Pathogenic	0.594
BRCA1	P38398-1.2	Q934L	Pathogenic	0.77
BRCA1	P38398-1.2	Q934M	Pathogenic	0.62
BRCA1	P38398-1.2	Q934N	Pathogenic	0.665
BRCA1	P38398-1.2	Q934P	Pathogenic	0.764
BRCA1	P38398-1.2	Q934R	Pathogenic	0.662
BRCA1	P38398-1.2	Q934S	Pathogenic	0.769
BRCA1	P38398-1.2	Q934T	Pathogenic	0.753
BRCA1	P38398-1.2	Q934V	Pathogenic	0.768
BRCA1	P38398-1.2	Q934W	Pathogenic	0.887
BRCA1	P38398-1.2	Q934Y	Pathogenic	0.775
BRCA1	P38398-1.2	K935A	Neutral	0.217
BRCA1	P38398-1.2	K935C	Neutral	0.271
BRCA1	P38398-1.2	K935D	Neutral	0.142
BRCA1	P38398-1.2	K935E	Neutral	0.051
BRCA1	P38398-1.2	K935F	Neutral	0.11
BRCA1	P38398-1.2	K935G	Neutral	0.379
BRCA1	P38398-1.2	K935H	Neutral	0.082
BRCA1	P38398-1.2	K935I	Neutral	0.136
BRCA1	P38398-1.2	K935L	Neutral	0.099
BRCA1	P38398-1.2	K935M	Neutral	0.071
BRCA1	P38398-1.2	K935N	Neutral	0.093
BRCA1	P38398-1.2	K935P	Neutral	0.141
BRCA1	P38398-1.2	K935Q	Neutral	0.045
BRCA1	P38398-1.2	K935R	Neutral	0.027
BRCA1	P38398-1.2	K935S	Neutral	0.145
BRCA1	P38398-1.2	K935T	Neutral	0.135
BRCA1	P38398-1.2	K935V	Neutral	0.144
BRCA1	P38398-1.2	K935W	Neutral	0.185
BRCA1	P38398-1.2	K935Y	Neutral	0.09
BRCA1	P38398-1.2	D936A	Neutral	0.051
BRCA1	P38398-1.2	D936C	Neutral	0.048
BRCA1	P38398-1.2	D936E	Neutral	0.011
BRCA1	P38398-1.2	D936F	Neutral	0.105
BRCA1	P38398-1.2	D936G	Neutral	0.054
BRCA1	P38398-1.2	D936H	Neutral	0.039
BRCA1	P38398-1.2	D936I	Neutral	0.085
BRCA1	P38398-1.2	D936K	Neutral	0.056
BRCA1	P38398-1.2	D936L	Neutral	0.117
BRCA1	P38398-1.2	D936M	Neutral	0.085
BRCA1	P38398-1.2	D936N	Neutral	0.012
BRCA1	P38398-1.2	D936P	Neutral	0.022
BRCA1	P38398-1.2	D936Q	Neutral	0.025
BRCA1	P38398-1.2	D936R	Neutral	0.103
BRCA1	P38398-1.2	D936S	Neutral	0.022
BRCA1	P38398-1.2	D936T	Neutral	0.023
BRCA1	P38398-1.2	D936V	Neutral	0.058
BRCA1	P38398-1.2	D936W	Neutral	0.238
BRCA1	P38398-1.2	D936Y	Neutral	0.12
BRCA1	P38398-1.2	K937A	Neutral	0.401
BRCA1	P38398-1.2	K937C	Neutral	0.473
BRCA1	P38398-1.2	K937D	Neutral	0.287
BRCA1	P38398-1.2	K937E	Neutral	0.115
BRCA1	P38398-1.2	K937F	Neutral	0.23
BRCA1	P38398-1.2	K937G	Pathogenic	0.597
BRCA1	P38398-1.2	K937H	Neutral	0.178
BRCA1	P38398-1.2	K937I	Neutral	0.276
BRCA1	P38398-1.2	K937L	Neutral	0.209
BRCA1	P38398-1.2	K937M	Neutral	0.157
BRCA1	P38398-1.2	K937N	Neutral	0.199
BRCA1	P38398-1.2	K937P	Neutral	0.285
BRCA1	P38398-1.2	K937Q	Neutral	0.103
BRCA1	P38398-1.2	K937R	Neutral	0.064
BRCA1	P38398-1.2	K937S	Neutral	0.291
BRCA1	P38398-1.2	K937T	Neutral	0.274
BRCA1	P38398-1.2	K937V	Neutral	0.29
BRCA1	P38398-1.2	K937W	Neutral	0.355
BRCA1	P38398-1.2	K937Y	Neutral	0.194
BRCA1	P38398-1.2	P938A	Pathogenic	0.671
BRCA1	P38398-1.2	P938C	Pathogenic	0.735
BRCA1	P38398-1.2	P938D	Pathogenic	0.55
BRCA1	P38398-1.2	P938E	Pathogenic	0.646
BRCA1	P38398-1.2	P938F	Pathogenic	0.907
BRCA1	P38398-1.2	P938G	Pathogenic	0.816
BRCA1	P38398-1.2	P938H	Pathogenic	0.765
BRCA1	P38398-1.2	P938I	Pathogenic	0.842
BRCA1	P38398-1.2	P938K	Pathogenic	0.764
BRCA1	P38398-1.2	P938L	Pathogenic	0.842
BRCA1	P38398-1.2	P938M	Pathogenic	0.789
BRCA1	P38398-1.2	P938N	Pathogenic	0.664
BRCA1	P38398-1.2	P938Q	Pathogenic	0.673
BRCA1	P38398-1.2	P938R	Pathogenic	0.861
BRCA1	P38398-1.2	P938S	Pathogenic	0.639
BRCA1	P38398-1.2	P938T	Pathogenic	0.566
BRCA1	P38398-1.2	P938V	Pathogenic	0.71
BRCA1	P38398-1.2	P938W	Pathogenic	0.947
BRCA1	P38398-1.2	P938Y	Pathogenic	0.887
BRCA1	P38398-1.2	V939A	Neutral	0.019
BRCA1	P38398-1.2	V939C	Neutral	0.018
BRCA1	P38398-1.2	V939D	Neutral	0.032
BRCA1	P38398-1.2	V939E	Neutral	0.018
BRCA1	P38398-1.2	V939F	Neutral	0.023
BRCA1	P38398-1.2	V939G	Neutral	0.081
BRCA1	P38398-1.2	V939H	Neutral	0.032
BRCA1	P38398-1.2	V939I	Neutral	0.004
BRCA1	P38398-1.2	V939K	Neutral	0.032
BRCA1	P38398-1.2	V939L	Neutral	0.009
BRCA1	P38398-1.2	V939M	Neutral	0.009
BRCA1	P38398-1.2	V939N	Neutral	0.029
BRCA1	P38398-1.2	V939P	Neutral	0.024
BRCA1	P38398-1.2	V939Q	Neutral	0.02
BRCA1	P38398-1.2	V939R	Neutral	0.059
BRCA1	P38398-1.2	V939S	Neutral	0.034
BRCA1	P38398-1.2	V939T	Neutral	0.011
BRCA1	P38398-1.2	V939W	Neutral	0.083
BRCA1	P38398-1.2	V939Y	Neutral	0.026
BRCA1	P38398-1.2	D940A	Neutral	0.104
BRCA1	P38398-1.2	D940C	Neutral	0.098
BRCA1	P38398-1.2	D940E	Neutral	0.024
BRCA1	P38398-1.2	D940F	Neutral	0.202
BRCA1	P38398-1.2	D940G	Neutral	0.11
BRCA1	P38398-1.2	D940H	Neutral	0.08
BRCA1	P38398-1.2	D940I	Neutral	0.166
BRCA1	P38398-1.2	D940K	Neutral	0.114
BRCA1	P38398-1.2	D940L	Neutral	0.223
BRCA1	P38398-1.2	D940M	Neutral	0.167
BRCA1	P38398-1.2	D940N	Neutral	0.025
BRCA1	P38398-1.2	D940P	Neutral	0.046
BRCA1	P38398-1.2	D940Q	Neutral	0.053
BRCA1	P38398-1.2	D940R	Neutral	0.198
BRCA1	P38398-1.2	D940S	Neutral	0.047
BRCA1	P38398-1.2	D940T	Neutral	0.047
BRCA1	P38398-1.2	D940V	Neutral	0.116
BRCA1	P38398-1.2	D940W	Neutral	0.403
BRCA1	P38398-1.2	D940Y	Neutral	0.228
BRCA1	P38398-1.2	N941A	Neutral	0.001
BRCA1	P38398-1.2	N941C	Neutral	0.001
BRCA1	P38398-1.2	N941D	Neutral	0.0
BRCA1	P38398-1.2	N941E	Neutral	0.0
BRCA1	P38398-1.2	N941F	Neutral	0.002
BRCA1	P38398-1.2	N941G	Neutral	0.001
BRCA1	P38398-1.2	N941H	Neutral	0.0
BRCA1	P38398-1.2	N941I	Neutral	0.001
BRCA1	P38398-1.2	N941K	Neutral	0.001
BRCA1	P38398-1.2	N941L	Neutral	0.001
BRCA1	P38398-1.2	N941M	Neutral	0.001
BRCA1	P38398-1.2	N941P	Neutral	0.001
BRCA1	P38398-1.2	N941Q	Neutral	0.0
BRCA1	P38398-1.2	N941R	Neutral	0.001
BRCA1	P38398-1.2	N941S	Neutral	0.0
BRCA1	P38398-1.2	N941T	Neutral	0.0
BRCA1	P38398-1.2	N941V	Neutral	0.001
BRCA1	P38398-1.2	N941W	Neutral	0.004
BRCA1	P38398-1.2	N941Y	Neutral	0.001
BRCA1	P38398-1.2	A942C	Neutral	0.309
BRCA1	P38398-1.2	A942D	Pathogenic	0.506
BRCA1	P38398-1.2	A942E	Pathogenic	0.516
BRCA1	P38398-1.2	A942F	Pathogenic	0.73
BRCA1	P38398-1.2	A942G	Neutral	0.31
BRCA1	P38398-1.2	A942H	Pathogenic	0.655
BRCA1	P38398-1.2	A942I	Pathogenic	0.595
BRCA1	P38398-1.2	A942K	Pathogenic	0.653
BRCA1	P38398-1.2	A942L	Pathogenic	0.596
BRCA1	P38398-1.2	A942M	Pathogenic	0.598
BRCA1	P38398-1.2	A942N	Pathogenic	0.535
BRCA1	P38398-1.2	A942P	Neutral	0.414
BRCA1	P38398-1.2	A942Q	Pathogenic	0.546
BRCA1	P38398-1.2	A942R	Pathogenic	0.716
BRCA1	P38398-1.2	A942S	Neutral	0.19
BRCA1	P38398-1.2	A942T	Neutral	0.346
BRCA1	P38398-1.2	A942V	Neutral	0.404
BRCA1	P38398-1.2	A942W	Pathogenic	0.878
BRCA1	P38398-1.2	A942Y	Pathogenic	0.758
BRCA1	P38398-1.2	K943A	Neutral	0.165
BRCA1	P38398-1.2	K943C	Neutral	0.209
BRCA1	P38398-1.2	K943D	Neutral	0.106
BRCA1	P38398-1.2	K943E	Neutral	0.037
BRCA1	P38398-1.2	K943F	Neutral	0.08
BRCA1	P38398-1.2	K943G	Neutral	0.303
BRCA1	P38398-1.2	K943H	Neutral	0.06
BRCA1	P38398-1.2	K943I	Neutral	0.1
BRCA1	P38398-1.2	K943L	Neutral	0.072
BRCA1	P38398-1.2	K943M	Neutral	0.052
BRCA1	P38398-1.2	K943N	Neutral	0.068
BRCA1	P38398-1.2	K943P	Neutral	0.105
BRCA1	P38398-1.2	K943Q	Neutral	0.033
BRCA1	P38398-1.2	K943R	Neutral	0.02
BRCA1	P38398-1.2	K943S	Neutral	0.108
BRCA1	P38398-1.2	K943T	Neutral	0.1
BRCA1	P38398-1.2	K943V	Neutral	0.107
BRCA1	P38398-1.2	K943W	Neutral	0.139
BRCA1	P38398-1.2	K943Y	Neutral	0.066
BRCA1	P38398-1.2	C944A	Neutral	0.021
BRCA1	P38398-1.2	C944D	Neutral	0.044
BRCA1	P38398-1.2	C944E	Neutral	0.091
BRCA1	P38398-1.2	C944F	Neutral	0.08
BRCA1	P38398-1.2	C944G	Neutral	0.09
BRCA1	P38398-1.2	C944H	Neutral	0.079
BRCA1	P38398-1.2	C944I	Neutral	0.045
BRCA1	P38398-1.2	C944K	Neutral	0.11
BRCA1	P38398-1.2	C944L	Neutral	0.046
BRCA1	P38398-1.2	C944M	Neutral	0.046
BRCA1	P38398-1.2	C944N	Neutral	0.05
BRCA1	P38398-1.2	C944P	Neutral	0.045
BRCA1	P38398-1.2	C944Q	Neutral	0.073
BRCA1	P38398-1.2	C944R	Neutral	0.141
BRCA1	P38398-1.2	C944S	Neutral	0.027
BRCA1	P38398-1.2	C944T	Neutral	0.023
BRCA1	P38398-1.2	C944V	Neutral	0.031
BRCA1	P38398-1.2	C944W	Neutral	0.139
BRCA1	P38398-1.2	C944Y	Neutral	0.092
BRCA1	P38398-1.2	S945A	Neutral	0.059
BRCA1	P38398-1.2	S945C	Neutral	0.129
BRCA1	P38398-1.2	S945D	Neutral	0.104
BRCA1	P38398-1.2	S945E	Neutral	0.148
BRCA1	P38398-1.2	S945F	Neutral	0.385
BRCA1	P38398-1.2	S945G	Neutral	0.121
BRCA1	P38398-1.2	S945H	Neutral	0.235
BRCA1	P38398-1.2	S945I	Neutral	0.329
BRCA1	P38398-1.2	S945K	Neutral	0.235
BRCA1	P38398-1.2	S945L	Neutral	0.329
BRCA1	P38398-1.2	S945M	Neutral	0.256
BRCA1	P38398-1.2	S945N	Neutral	0.083
BRCA1	P38398-1.2	S945P	Neutral	0.14
BRCA1	P38398-1.2	S945Q	Neutral	0.163
BRCA1	P38398-1.2	S945R	Neutral	0.371
BRCA1	P38398-1.2	S945T	Neutral	0.078
BRCA1	P38398-1.2	S945V	Neutral	0.245
BRCA1	P38398-1.2	S945W	Pathogenic	0.624
BRCA1	P38398-1.2	S945Y	Neutral	0.42
BRCA1	P38398-1.2	I946A	Neutral	0.027
BRCA1	P38398-1.2	I946C	Neutral	0.018
BRCA1	P38398-1.2	I946D	Neutral	0.032
BRCA1	P38398-1.2	I946E	Neutral	0.022
BRCA1	P38398-1.2	I946F	Neutral	0.007
BRCA1	P38398-1.2	I946G	Neutral	0.113
BRCA1	P38398-1.2	I946H	Neutral	0.018
BRCA1	P38398-1.2	I946K	Neutral	0.02
BRCA1	P38398-1.2	I946L	Neutral	0.003
BRCA1	P38398-1.2	I946M	Neutral	0.004
BRCA1	P38398-1.2	I946N	Neutral	0.029
BRCA1	P38398-1.2	I946P	Neutral	0.034
BRCA1	P38398-1.2	I946Q	Neutral	0.02
BRCA1	P38398-1.2	I946R	Neutral	0.027
BRCA1	P38398-1.2	I946S	Neutral	0.034
BRCA1	P38398-1.2	I946T	Neutral	0.016
BRCA1	P38398-1.2	I946V	Neutral	0.003
BRCA1	P38398-1.2	I946W	Neutral	0.038
BRCA1	P38398-1.2	I946Y	Neutral	0.012
BRCA1	P38398-1.2	K947A	Neutral	0.042
BRCA1	P38398-1.2	K947C	Neutral	0.055
BRCA1	P38398-1.2	K947D	Neutral	0.025
BRCA1	P38398-1.2	K947E	Neutral	0.008
BRCA1	P38398-1.2	K947F	Neutral	0.019
BRCA1	P38398-1.2	K947G	Neutral	0.088
BRCA1	P38398-1.2	K947H	Neutral	0.014
BRCA1	P38398-1.2	K947I	Neutral	0.024
BRCA1	P38398-1.2	K947L	Neutral	0.017
BRCA1	P38398-1.2	K947M	Neutral	0.012
BRCA1	P38398-1.2	K947N	Neutral	0.016
BRCA1	P38398-1.2	K947P	Neutral	0.025
BRCA1	P38398-1.2	K947Q	Neutral	0.007
BRCA1	P38398-1.2	K947R	Neutral	0.004
BRCA1	P38398-1.2	K947S	Neutral	0.026
BRCA1	P38398-1.2	K947T	Neutral	0.024
BRCA1	P38398-1.2	K947V	Neutral	0.026
BRCA1	P38398-1.2	K947W	Neutral	0.035
BRCA1	P38398-1.2	K947Y	Neutral	0.015
BRCA1	P38398-1.2	G948A	Neutral	0.056
BRCA1	P38398-1.2	G948C	Neutral	0.212
BRCA1	P38398-1.2	G948D	Neutral	0.127
BRCA1	P38398-1.2	G948E	Neutral	0.238
BRCA1	P38398-1.2	G948F	Neutral	0.44
BRCA1	P38398-1.2	G948H	Neutral	0.279
BRCA1	P38398-1.2	G948I	Neutral	0.469
BRCA1	P38398-1.2	G948K	Neutral	0.357
BRCA1	P38398-1.2	G948L	Neutral	0.47
BRCA1	P38398-1.2	G948M	Neutral	0.383
BRCA1	P38398-1.2	G948N	Neutral	0.102
BRCA1	P38398-1.2	G948P	Neutral	0.17
BRCA1	P38398-1.2	G948Q	Neutral	0.261
BRCA1	P38398-1.2	G948R	Neutral	0.425
BRCA1	P38398-1.2	G948S	Neutral	0.064
BRCA1	P38398-1.2	G948T	Neutral	0.181
BRCA1	P38398-1.2	G948V	Neutral	0.29
BRCA1	P38398-1.2	G948W	Pathogenic	0.502
BRCA1	P38398-1.2	G948Y	Neutral	0.477
BRCA1	P38398-1.2	G949A	Neutral	0.005
BRCA1	P38398-1.2	G949C	Neutral	0.023
BRCA1	P38398-1.2	G949D	Neutral	0.013
BRCA1	P38398-1.2	G949E	Neutral	0.027
BRCA1	P38398-1.2	G949F	Neutral	0.065
BRCA1	P38398-1.2	G949H	Neutral	0.033
BRCA1	P38398-1.2	G949I	Neutral	0.072
BRCA1	P38398-1.2	G949K	Neutral	0.047
BRCA1	P38398-1.2	G949L	Neutral	0.073
BRCA1	P38398-1.2	G949M	Neutral	0.052
BRCA1	P38398-1.2	G949N	Neutral	0.01
BRCA1	P38398-1.2	G949P	Neutral	0.018
BRCA1	P38398-1.2	G949Q	Neutral	0.03
BRCA1	P38398-1.2	G949R	Neutral	0.061
BRCA1	P38398-1.2	G949S	Neutral	0.006
BRCA1	P38398-1.2	G949T	Neutral	0.019
BRCA1	P38398-1.2	G949V	Neutral	0.035
BRCA1	P38398-1.2	G949W	Neutral	0.082
BRCA1	P38398-1.2	G949Y	Neutral	0.074
BRCA1	P38398-1.2	S950A	Neutral	0.182
BRCA1	P38398-1.2	S950C	Neutral	0.347
BRCA1	P38398-1.2	S950D	Neutral	0.293
BRCA1	P38398-1.2	S950E	Neutral	0.383
BRCA1	P38398-1.2	S950F	Pathogenic	0.691
BRCA1	P38398-1.2	S950G	Neutral	0.33
BRCA1	P38398-1.2	S950H	Pathogenic	0.524
BRCA1	P38398-1.2	S950I	Pathogenic	0.637
BRCA1	P38398-1.2	S950K	Pathogenic	0.524
BRCA1	P38398-1.2	S950L	Pathogenic	0.637
BRCA1	P38398-1.2	S950M	Pathogenic	0.552
BRCA1	P38398-1.2	S950N	Neutral	0.244
BRCA1	P38398-1.2	S950P	Neutral	0.369
BRCA1	P38398-1.2	S950Q	Neutral	0.412
BRCA1	P38398-1.2	S950R	Pathogenic	0.678
BRCA1	P38398-1.2	S950T	Neutral	0.233
BRCA1	P38398-1.2	S950V	Pathogenic	0.537
BRCA1	P38398-1.2	S950W	Pathogenic	0.856
BRCA1	P38398-1.2	S950Y	Pathogenic	0.722
BRCA1	P38398-1.2	R951A	Pathogenic	0.611
BRCA1	P38398-1.2	R951C	Pathogenic	0.678
BRCA1	P38398-1.2	R951D	Pathogenic	0.575
BRCA1	P38398-1.2	R951E	Neutral	0.304
BRCA1	P38398-1.2	R951F	Neutral	0.411
BRCA1	P38398-1.2	R951G	Pathogenic	0.776
BRCA1	P38398-1.2	R951H	Neutral	0.26
BRCA1	P38398-1.2	R951I	Neutral	0.471
BRCA1	P38398-1.2	R951K	Neutral	0.106
BRCA1	P38398-1.2	R951L	Neutral	0.382
BRCA1	P38398-1.2	R951M	Neutral	0.303
BRCA1	P38398-1.2	R951N	Neutral	0.368
BRCA1	P38398-1.2	R951P	Pathogenic	0.573
BRCA1	P38398-1.2	R951Q	Neutral	0.212
BRCA1	P38398-1.2	R951S	Pathogenic	0.58
BRCA1	P38398-1.2	R951T	Neutral	0.468
BRCA1	P38398-1.2	R951V	Pathogenic	0.578
BRCA1	P38398-1.2	R951W	Neutral	0.419
BRCA1	P38398-1.2	R951Y	Neutral	0.301
BRCA1	P38398-1.2	F952A	Neutral	0.212
BRCA1	P38398-1.2	F952C	Neutral	0.152
BRCA1	P38398-1.2	F952D	Neutral	0.182
BRCA1	P38398-1.2	F952E	Neutral	0.13
BRCA1	P38398-1.2	F952G	Neutral	0.37
BRCA1	P38398-1.2	F952H	Neutral	0.057
BRCA1	P38398-1.2	F952I	Neutral	0.036
BRCA1	P38398-1.2	F952K	Neutral	0.077
BRCA1	P38398-1.2	F952L	Neutral	0.036
BRCA1	P38398-1.2	F952M	Neutral	0.036
BRCA1	P38398-1.2	F952N	Neutral	0.167
BRCA1	P38398-1.2	F952P	Neutral	0.252
BRCA1	P38398-1.2	F952Q	Neutral	0.119
BRCA1	P38398-1.2	F952R	Neutral	0.1
BRCA1	P38398-1.2	F952S	Neutral	0.19
BRCA1	P38398-1.2	F952T	Neutral	0.131
BRCA1	P38398-1.2	F952V	Neutral	0.076
BRCA1	P38398-1.2	F952W	Neutral	0.037
BRCA1	P38398-1.2	F952Y	Neutral	0.011
BRCA1	P38398-1.2	C953A	Pathogenic	0.643
BRCA1	P38398-1.2	C953D	Pathogenic	0.794
BRCA1	P38398-1.2	C953E	Pathogenic	0.892
BRCA1	P38398-1.2	C953F	Pathogenic	0.879
BRCA1	P38398-1.2	C953G	Pathogenic	0.891
BRCA1	P38398-1.2	C953H	Pathogenic	0.877
BRCA1	P38398-1.2	C953I	Pathogenic	0.798
BRCA1	P38398-1.2	C953K	Pathogenic	0.911
BRCA1	P38398-1.2	C953L	Pathogenic	0.798
BRCA1	P38398-1.2	C953M	Pathogenic	0.8
BRCA1	P38398-1.2	C953N	Pathogenic	0.812
BRCA1	P38398-1.2	C953P	Pathogenic	0.795
BRCA1	P38398-1.2	C953Q	Pathogenic	0.867
BRCA1	P38398-1.2	C953R	Pathogenic	0.932
BRCA1	P38398-1.2	C953S	Pathogenic	0.693
BRCA1	P38398-1.2	C953T	Pathogenic	0.665
BRCA1	P38398-1.2	C953V	Pathogenic	0.723
BRCA1	P38398-1.2	C953W	Pathogenic	0.93
BRCA1	P38398-1.2	C953Y	Pathogenic	0.894
BRCA1	P38398-1.2	L954A	Neutral	0.022
BRCA1	P38398-1.2	L954C	Neutral	0.015
BRCA1	P38398-1.2	L954D	Neutral	0.037
BRCA1	P38398-1.2	L954E	Neutral	0.018
BRCA1	P38398-1.2	L954F	Neutral	0.006
BRCA1	P38398-1.2	L954G	Neutral	0.093
BRCA1	P38398-1.2	L954H	Neutral	0.015
BRCA1	P38398-1.2	L954I	Neutral	0.002
BRCA1	P38398-1.2	L954K	Neutral	0.011
BRCA1	P38398-1.2	L954M	Neutral	0.002
BRCA1	P38398-1.2	L954N	Neutral	0.024
BRCA1	P38398-1.2	L954P	Neutral	0.028
BRCA1	P38398-1.2	L954Q	Neutral	0.011
BRCA1	P38398-1.2	L954R	Neutral	0.015
BRCA1	P38398-1.2	L954S	Neutral	0.028
BRCA1	P38398-1.2	L954T	Neutral	0.013
BRCA1	P38398-1.2	L954V	Neutral	0.005
BRCA1	P38398-1.2	L954W	Neutral	0.022
BRCA1	P38398-1.2	L954Y	Neutral	0.009
BRCA1	P38398-1.2	S955A	Neutral	0.481
BRCA1	P38398-1.2	S955C	Pathogenic	0.688
BRCA1	P38398-1.2	S955D	Pathogenic	0.633
BRCA1	P38398-1.2	S955E	Pathogenic	0.721
BRCA1	P38398-1.2	S955F	Pathogenic	0.903
BRCA1	P38398-1.2	S955G	Pathogenic	0.671
BRCA1	P38398-1.2	S955H	Pathogenic	0.821
BRCA1	P38398-1.2	S955I	Pathogenic	0.879
BRCA1	P38398-1.2	S955K	Pathogenic	0.82
BRCA1	P38398-1.2	S955L	Pathogenic	0.879
BRCA1	P38398-1.2	S955M	Pathogenic	0.836
BRCA1	P38398-1.2	S955N	Pathogenic	0.573
BRCA1	P38398-1.2	S955P	Pathogenic	0.708
BRCA1	P38398-1.2	S955Q	Pathogenic	0.744
BRCA1	P38398-1.2	S955R	Pathogenic	0.898
BRCA1	P38398-1.2	S955T	Pathogenic	0.558
BRCA1	P38398-1.2	S955V	Pathogenic	0.828
BRCA1	P38398-1.2	S955W	Pathogenic	0.961
BRCA1	P38398-1.2	S955Y	Pathogenic	0.915
BRCA1	P38398-1.2	S956A	Neutral	0.155
BRCA1	P38398-1.2	S956C	Neutral	0.305
BRCA1	P38398-1.2	S956D	Neutral	0.255
BRCA1	P38398-1.2	S956E	Neutral	0.339
BRCA1	P38398-1.2	S956F	Pathogenic	0.649
BRCA1	P38398-1.2	S956G	Neutral	0.289
BRCA1	P38398-1.2	S956H	Neutral	0.476
BRCA1	P38398-1.2	S956I	Pathogenic	0.591
BRCA1	P38398-1.2	S956K	Neutral	0.475
BRCA1	P38398-1.2	S956L	Pathogenic	0.592
BRCA1	P38398-1.2	S956M	Pathogenic	0.504
BRCA1	P38398-1.2	S956N	Neutral	0.211
BRCA1	P38398-1.2	S956P	Neutral	0.325
BRCA1	P38398-1.2	S956Q	Neutral	0.366
BRCA1	P38398-1.2	S956R	Pathogenic	0.635
BRCA1	P38398-1.2	S956T	Neutral	0.201
BRCA1	P38398-1.2	S956V	Neutral	0.489
BRCA1	P38398-1.2	S956W	Pathogenic	0.831
BRCA1	P38398-1.2	S956Y	Pathogenic	0.682
BRCA1	P38398-1.2	Q957A	Pathogenic	0.871
BRCA1	P38398-1.2	Q957C	Pathogenic	0.901
BRCA1	P38398-1.2	Q957D	Pathogenic	0.734
BRCA1	P38398-1.2	Q957E	Neutral	0.472
BRCA1	P38398-1.2	Q957F	Pathogenic	0.884
BRCA1	P38398-1.2	Q957G	Pathogenic	0.937
BRCA1	P38398-1.2	Q957H	Pathogenic	0.645
BRCA1	P38398-1.2	Q957I	Pathogenic	0.857
BRCA1	P38398-1.2	Q957K	Pathogenic	0.646
BRCA1	P38398-1.2	Q957L	Pathogenic	0.806
BRCA1	P38398-1.2	Q957M	Pathogenic	0.67
BRCA1	P38398-1.2	Q957N	Pathogenic	0.712
BRCA1	P38398-1.2	Q957P	Pathogenic	0.801
BRCA1	P38398-1.2	Q957R	Pathogenic	0.709
BRCA1	P38398-1.2	Q957S	Pathogenic	0.805
BRCA1	P38398-1.2	Q957T	Pathogenic	0.792
BRCA1	P38398-1.2	Q957V	Pathogenic	0.804
BRCA1	P38398-1.2	Q957W	Pathogenic	0.907
BRCA1	P38398-1.2	Q957Y	Pathogenic	0.811
BRCA1	P38398-1.2	F958A	Neutral	0.326
BRCA1	P38398-1.2	F958C	Neutral	0.243
BRCA1	P38398-1.2	F958D	Neutral	0.286
BRCA1	P38398-1.2	F958E	Neutral	0.212
BRCA1	P38398-1.2	F958G	Pathogenic	0.513
BRCA1	P38398-1.2	F958H	Neutral	0.097
BRCA1	P38398-1.2	F958I	Neutral	0.063
BRCA1	P38398-1.2	F958K	Neutral	0.13
BRCA1	P38398-1.2	F958L	Neutral	0.063
BRCA1	P38398-1.2	F958M	Neutral	0.063
BRCA1	P38398-1.2	F958N	Neutral	0.264
BRCA1	P38398-1.2	F958P	Neutral	0.377
BRCA1	P38398-1.2	F958Q	Neutral	0.195
BRCA1	P38398-1.2	F958R	Neutral	0.167
BRCA1	P38398-1.2	F958S	Neutral	0.296
BRCA1	P38398-1.2	F958T	Neutral	0.213
BRCA1	P38398-1.2	F958V	Neutral	0.128
BRCA1	P38398-1.2	F958W	Neutral	0.064
BRCA1	P38398-1.2	F958Y	Neutral	0.02
BRCA1	P38398-1.2	R959A	Pathogenic	0.686
BRCA1	P38398-1.2	R959C	Pathogenic	0.745
BRCA1	P38398-1.2	R959D	Pathogenic	0.653
BRCA1	P38398-1.2	R959E	Neutral	0.378
BRCA1	P38398-1.2	R959F	Neutral	0.493
BRCA1	P38398-1.2	R959G	Pathogenic	0.828
BRCA1	P38398-1.2	R959H	Neutral	0.329
BRCA1	P38398-1.2	R959I	Pathogenic	0.553
BRCA1	P38398-1.2	R959K	Neutral	0.142
BRCA1	P38398-1.2	R959L	Neutral	0.463
BRCA1	P38398-1.2	R959M	Neutral	0.377
BRCA1	P38398-1.2	R959N	Neutral	0.448
BRCA1	P38398-1.2	R959P	Pathogenic	0.652
BRCA1	P38398-1.2	R959Q	Neutral	0.273
BRCA1	P38398-1.2	R959S	Pathogenic	0.658
BRCA1	P38398-1.2	R959T	Pathogenic	0.551
BRCA1	P38398-1.2	R959V	Pathogenic	0.656
BRCA1	P38398-1.2	R959W	Pathogenic	0.501
BRCA1	P38398-1.2	R959Y	Neutral	0.375
BRCA1	P38398-1.2	G960A	Pathogenic	0.502
BRCA1	P38398-1.2	G960C	Pathogenic	0.819
BRCA1	P38398-1.2	G960D	Pathogenic	0.71
BRCA1	P38398-1.2	G960E	Pathogenic	0.841
BRCA1	P38398-1.2	G960F	Pathogenic	0.93
BRCA1	P38398-1.2	G960H	Pathogenic	0.867
BRCA1	P38398-1.2	G960I	Pathogenic	0.937
BRCA1	P38398-1.2	G960K	Pathogenic	0.903
BRCA1	P38398-1.2	G960L	Pathogenic	0.937
BRCA1	P38398-1.2	G960M	Pathogenic	0.913
BRCA1	P38398-1.2	G960N	Pathogenic	0.657
BRCA1	P38398-1.2	G960P	Pathogenic	0.776
BRCA1	P38398-1.2	G960Q	Pathogenic	0.856
BRCA1	P38398-1.2	G960R	Pathogenic	0.926
BRCA1	P38398-1.2	G960S	Pathogenic	0.537
BRCA1	P38398-1.2	G960T	Pathogenic	0.788
BRCA1	P38398-1.2	G960V	Pathogenic	0.873
BRCA1	P38398-1.2	G960W	Pathogenic	0.944
BRCA1	P38398-1.2	G960Y	Pathogenic	0.939
BRCA1	P38398-1.2	N961A	Neutral	0.035
BRCA1	P38398-1.2	N961C	Neutral	0.033
BRCA1	P38398-1.2	N961D	Neutral	0.007
BRCA1	P38398-1.2	N961E	Neutral	0.012
BRCA1	P38398-1.2	N961F	Neutral	0.06
BRCA1	P38398-1.2	N961G	Neutral	0.026
BRCA1	P38398-1.2	N961H	Neutral	0.01
BRCA1	P38398-1.2	N961I	Neutral	0.048
BRCA1	P38398-1.2	N961K	Neutral	0.022
BRCA1	P38398-1.2	N961L	Neutral	0.048
BRCA1	P38398-1.2	N961M	Neutral	0.034
BRCA1	P38398-1.2	N961P	Neutral	0.021
BRCA1	P38398-1.2	N961Q	Neutral	0.014
BRCA1	P38398-1.2	N961R	Neutral	0.029
BRCA1	P38398-1.2	N961S	Neutral	0.011
BRCA1	P38398-1.2	N961T	Neutral	0.01
BRCA1	P38398-1.2	N961V	Neutral	0.032
BRCA1	P38398-1.2	N961W	Neutral	0.145
BRCA1	P38398-1.2	N961Y	Neutral	0.049
BRCA1	P38398-1.2	E962A	Neutral	0.431
BRCA1	P38398-1.2	E962C	Pathogenic	0.594
BRCA1	P38398-1.2	E962D	Neutral	0.132
BRCA1	P38398-1.2	E962F	Pathogenic	0.517
BRCA1	P38398-1.2	E962G	Pathogenic	0.626
BRCA1	P38398-1.2	E962H	Neutral	0.202
BRCA1	P38398-1.2	E962I	Neutral	0.456
BRCA1	P38398-1.2	E962K	Neutral	0.206
BRCA1	P38398-1.2	E962L	Neutral	0.456
BRCA1	P38398-1.2	E962M	Neutral	0.37
BRCA1	P38398-1.2	E962N	Neutral	0.22
BRCA1	P38398-1.2	E962P	Neutral	0.311
BRCA1	P38398-1.2	E962Q	Neutral	0.101
BRCA1	P38398-1.2	E962R	Neutral	0.333
BRCA1	P38398-1.2	E962S	Neutral	0.317
BRCA1	P38398-1.2	E962T	Neutral	0.299
BRCA1	P38398-1.2	E962V	Neutral	0.315
BRCA1	P38398-1.2	E962W	Pathogenic	0.664
BRCA1	P38398-1.2	E962Y	Neutral	0.463
BRCA1	P38398-1.2	T963A	Neutral	0.146
BRCA1	P38398-1.2	T963C	Neutral	0.138
BRCA1	P38398-1.2	T963D	Neutral	0.124
BRCA1	P38398-1.2	T963E	Neutral	0.163
BRCA1	P38398-1.2	T963F	Neutral	0.33
BRCA1	P38398-1.2	T963G	Neutral	0.35
BRCA1	P38398-1.2	T963H	Neutral	0.257
BRCA1	P38398-1.2	T963I	Neutral	0.211
BRCA1	P38398-1.2	T963K	Neutral	0.256
BRCA1	P38398-1.2	T963L	Neutral	0.211
BRCA1	P38398-1.2	T963M	Neutral	0.213
BRCA1	P38398-1.2	T963N	Neutral	0.092
BRCA1	P38398-1.2	T963P	Neutral	0.128
BRCA1	P38398-1.2	T963Q	Neutral	0.18
BRCA1	P38398-1.2	T963R	Neutral	0.314
BRCA1	P38398-1.2	T963S	Neutral	0.094
BRCA1	P38398-1.2	T963V	Neutral	0.11
BRCA1	P38398-1.2	T963W	Neutral	0.476
BRCA1	P38398-1.2	T963Y	Neutral	0.364
BRCA1	P38398-1.2	G964A	Neutral	0.1
BRCA1	P38398-1.2	G964C	Neutral	0.332
BRCA1	P38398-1.2	G964D	Neutral	0.212
BRCA1	P38398-1.2	G964E	Neutral	0.367
BRCA1	P38398-1.2	G964F	Pathogenic	0.592
BRCA1	P38398-1.2	G964H	Neutral	0.417
BRCA1	P38398-1.2	G964I	Pathogenic	0.621
BRCA1	P38398-1.2	G964K	Pathogenic	0.506
BRCA1	P38398-1.2	G964L	Pathogenic	0.621
BRCA1	P38398-1.2	G964M	Pathogenic	0.535
BRCA1	P38398-1.2	G964N	Neutral	0.173
BRCA1	P38398-1.2	G964P	Neutral	0.275
BRCA1	P38398-1.2	G964Q	Neutral	0.395
BRCA1	P38398-1.2	G964R	Pathogenic	0.578
BRCA1	P38398-1.2	G964S	Neutral	0.113
BRCA1	P38398-1.2	G964T	Neutral	0.29
BRCA1	P38398-1.2	G964V	Neutral	0.43
BRCA1	P38398-1.2	G964W	Pathogenic	0.651
BRCA1	P38398-1.2	G964Y	Pathogenic	0.628
BRCA1	P38398-1.2	L965A	Neutral	0.466
BRCA1	P38398-1.2	L965C	Neutral	0.367
BRCA1	P38398-1.2	L965D	Pathogenic	0.599
BRCA1	P38398-1.2	L965E	Neutral	0.411
BRCA1	P38398-1.2	L965F	Neutral	0.183
BRCA1	P38398-1.2	L965G	Pathogenic	0.798
BRCA1	P38398-1.2	L965H	Neutral	0.367
BRCA1	P38398-1.2	L965I	Neutral	0.078
BRCA1	P38398-1.2	L965K	Neutral	0.306
BRCA1	P38398-1.2	L965M	Neutral	0.077
BRCA1	P38398-1.2	L965N	Neutral	0.482
BRCA1	P38398-1.2	L965P	Pathogenic	0.522
BRCA1	P38398-1.2	L965Q	Neutral	0.304
BRCA1	P38398-1.2	L965R	Neutral	0.37
BRCA1	P38398-1.2	L965S	Pathogenic	0.522
BRCA1	P38398-1.2	L965T	Neutral	0.328
BRCA1	P38398-1.2	L965V	Neutral	0.156
BRCA1	P38398-1.2	L965W	Neutral	0.461
BRCA1	P38398-1.2	L965Y	Neutral	0.266
BRCA1	P38398-1.2	I966A	Neutral	0.074
BRCA1	P38398-1.2	I966C	Neutral	0.05
BRCA1	P38398-1.2	I966D	Neutral	0.087
BRCA1	P38398-1.2	I966E	Neutral	0.06
BRCA1	P38398-1.2	I966F	Neutral	0.02
BRCA1	P38398-1.2	I966G	Neutral	0.265
BRCA1	P38398-1.2	I966H	Neutral	0.05
BRCA1	P38398-1.2	I966K	Neutral	0.055
BRCA1	P38398-1.2	I966L	Neutral	0.008
BRCA1	P38398-1.2	I966M	Neutral	0.011
BRCA1	P38398-1.2	I966N	Neutral	0.079
BRCA1	P38398-1.2	I966P	Neutral	0.091
BRCA1	P38398-1.2	I966Q	Neutral	0.055
BRCA1	P38398-1.2	I966R	Neutral	0.072
BRCA1	P38398-1.2	I966S	Neutral	0.091
BRCA1	P38398-1.2	I966T	Neutral	0.043
BRCA1	P38398-1.2	I966V	Neutral	0.008
BRCA1	P38398-1.2	I966W	Neutral	0.102
BRCA1	P38398-1.2	I966Y	Neutral	0.032
BRCA1	P38398-1.2	T967A	Neutral	0.003
BRCA1	P38398-1.2	T967C	Neutral	0.003
BRCA1	P38398-1.2	T967D	Neutral	0.002
BRCA1	P38398-1.2	T967E	Neutral	0.003
BRCA1	P38398-1.2	T967F	Neutral	0.008
BRCA1	P38398-1.2	T967G	Neutral	0.009
BRCA1	P38398-1.2	T967H	Neutral	0.005
BRCA1	P38398-1.2	T967I	Neutral	0.004
BRCA1	P38398-1.2	T967K	Neutral	0.005
BRCA1	P38398-1.2	T967L	Neutral	0.004
BRCA1	P38398-1.2	T967M	Neutral	0.004
BRCA1	P38398-1.2	T967N	Neutral	0.002
BRCA1	P38398-1.2	T967P	Neutral	0.002
BRCA1	P38398-1.2	T967Q	Neutral	0.003
BRCA1	P38398-1.2	T967R	Neutral	0.007
BRCA1	P38398-1.2	T967S	Neutral	0.002
BRCA1	P38398-1.2	T967V	Neutral	0.002
BRCA1	P38398-1.2	T967W	Neutral	0.014
BRCA1	P38398-1.2	T967Y	Neutral	0.009
BRCA1	P38398-1.2	P968A	Neutral	0.014
BRCA1	P38398-1.2	P968C	Neutral	0.018
BRCA1	P38398-1.2	P968D	Neutral	0.008
BRCA1	P38398-1.2	P968E	Neutral	0.012
BRCA1	P38398-1.2	P968F	Neutral	0.062
BRCA1	P38398-1.2	P968G	Neutral	0.029
BRCA1	P38398-1.2	P968H	Neutral	0.022
BRCA1	P38398-1.2	P968I	Neutral	0.035
BRCA1	P38398-1.2	P968K	Neutral	0.021
BRCA1	P38398-1.2	P968L	Neutral	0.035
BRCA1	P38398-1.2	P968M	Neutral	0.025
BRCA1	P38398-1.2	P968N	Neutral	0.013
BRCA1	P38398-1.2	P968Q	Neutral	0.014
BRCA1	P38398-1.2	P968R	Neutral	0.04
BRCA1	P38398-1.2	P968S	Neutral	0.012
BRCA1	P38398-1.2	P968T	Neutral	0.009
BRCA1	P38398-1.2	P968V	Neutral	0.016
BRCA1	P38398-1.2	P968W	Neutral	0.108
BRCA1	P38398-1.2	P968Y	Neutral	0.05
BRCA1	P38398-1.2	N969A	Neutral	0.276
BRCA1	P38398-1.2	N969C	Neutral	0.262
BRCA1	P38398-1.2	N969D	Neutral	0.071
BRCA1	P38398-1.2	N969E	Neutral	0.116
BRCA1	P38398-1.2	N969F	Neutral	0.4
BRCA1	P38398-1.2	N969G	Neutral	0.22
BRCA1	P38398-1.2	N969H	Neutral	0.099
BRCA1	P38398-1.2	N969I	Neutral	0.343
BRCA1	P38398-1.2	N969K	Neutral	0.189
BRCA1	P38398-1.2	N969L	Neutral	0.343
BRCA1	P38398-1.2	N969M	Neutral	0.268
BRCA1	P38398-1.2	N969P	Neutral	0.185
BRCA1	P38398-1.2	N969Q	Neutral	0.127
BRCA1	P38398-1.2	N969R	Neutral	0.237
BRCA1	P38398-1.2	N969S	Neutral	0.101
BRCA1	P38398-1.2	N969T	Neutral	0.094
BRCA1	P38398-1.2	N969V	Neutral	0.257
BRCA1	P38398-1.2	N969W	Pathogenic	0.639
BRCA1	P38398-1.2	N969Y	Neutral	0.35
BRCA1	P38398-1.2	K970A	Neutral	0.296
BRCA1	P38398-1.2	K970C	Neutral	0.36
BRCA1	P38398-1.2	K970D	Neutral	0.201
BRCA1	P38398-1.2	K970E	Neutral	0.075
BRCA1	P38398-1.2	K970F	Neutral	0.157
BRCA1	P38398-1.2	K970G	Neutral	0.481
BRCA1	P38398-1.2	K970H	Neutral	0.12
BRCA1	P38398-1.2	K970I	Neutral	0.193
BRCA1	P38398-1.2	K970L	Neutral	0.142
BRCA1	P38398-1.2	K970M	Neutral	0.104
BRCA1	P38398-1.2	K970N	Neutral	0.135
BRCA1	P38398-1.2	K970P	Neutral	0.2
BRCA1	P38398-1.2	K970Q	Neutral	0.067
BRCA1	P38398-1.2	K970R	Neutral	0.041
BRCA1	P38398-1.2	K970S	Neutral	0.205
BRCA1	P38398-1.2	K970T	Neutral	0.191
BRCA1	P38398-1.2	K970V	Neutral	0.204
BRCA1	P38398-1.2	K970W	Neutral	0.256
BRCA1	P38398-1.2	K970Y	Neutral	0.131
BRCA1	P38398-1.2	H971A	Neutral	0.022
BRCA1	P38398-1.2	H971C	Neutral	0.02
BRCA1	P38398-1.2	H971D	Neutral	0.009
BRCA1	P38398-1.2	H971E	Neutral	0.004
BRCA1	P38398-1.2	H971F	Neutral	0.007
BRCA1	P38398-1.2	H971G	Neutral	0.033
BRCA1	P38398-1.2	H971I	Neutral	0.011
BRCA1	P38398-1.2	H971K	Neutral	0.007
BRCA1	P38398-1.2	H971L	Neutral	0.011
BRCA1	P38398-1.2	H971M	Neutral	0.008
BRCA1	P38398-1.2	H971N	Neutral	0.004
BRCA1	P38398-1.2	H971P	Neutral	0.013
BRCA1	P38398-1.2	H971Q	Neutral	0.004
BRCA1	P38398-1.2	H971R	Neutral	0.007
BRCA1	P38398-1.2	H971S	Neutral	0.013
BRCA1	P38398-1.2	H971T	Neutral	0.012
BRCA1	P38398-1.2	H971V	Neutral	0.013
BRCA1	P38398-1.2	H971W	Neutral	0.018
BRCA1	P38398-1.2	H971Y	Neutral	0.003
BRCA1	P38398-1.2	G972A	Neutral	0.181
BRCA1	P38398-1.2	G972C	Neutral	0.498
BRCA1	P38398-1.2	G972D	Neutral	0.35
BRCA1	P38398-1.2	G972E	Pathogenic	0.536
BRCA1	P38398-1.2	G972F	Pathogenic	0.744
BRCA1	P38398-1.2	G972H	Pathogenic	0.588
BRCA1	P38398-1.2	G972I	Pathogenic	0.766
BRCA1	P38398-1.2	G972K	Pathogenic	0.672
BRCA1	P38398-1.2	G972L	Pathogenic	0.766
BRCA1	P38398-1.2	G972M	Pathogenic	0.697
BRCA1	P38398-1.2	G972N	Neutral	0.295
BRCA1	P38398-1.2	G972P	Neutral	0.431
BRCA1	P38398-1.2	G972Q	Pathogenic	0.566
BRCA1	P38398-1.2	G972R	Pathogenic	0.732
BRCA1	P38398-1.2	G972S	Neutral	0.203
BRCA1	P38398-1.2	G972T	Neutral	0.45
BRCA1	P38398-1.2	G972V	Pathogenic	0.601
BRCA1	P38398-1.2	G972W	Pathogenic	0.788
BRCA1	P38398-1.2	G972Y	Pathogenic	0.771
BRCA1	P38398-1.2	L973A	Neutral	0.204
BRCA1	P38398-1.2	L973C	Neutral	0.146
BRCA1	P38398-1.2	L973D	Neutral	0.306
BRCA1	P38398-1.2	L973E	Neutral	0.17
BRCA1	P38398-1.2	L973F	Neutral	0.062
BRCA1	P38398-1.2	L973G	Pathogenic	0.537
BRCA1	P38398-1.2	L973H	Neutral	0.146
BRCA1	P38398-1.2	L973I	Neutral	0.024
BRCA1	P38398-1.2	L973K	Neutral	0.115
BRCA1	P38398-1.2	L973M	Neutral	0.024
BRCA1	P38398-1.2	L973N	Neutral	0.215
BRCA1	P38398-1.2	L973P	Neutral	0.243
BRCA1	P38398-1.2	L973Q	Neutral	0.114
BRCA1	P38398-1.2	L973R	Neutral	0.148
BRCA1	P38398-1.2	L973S	Neutral	0.243
BRCA1	P38398-1.2	L973T	Neutral	0.126
BRCA1	P38398-1.2	L973V	Neutral	0.051
BRCA1	P38398-1.2	L973W	Neutral	0.201
BRCA1	P38398-1.2	L973Y	Neutral	0.097
BRCA1	P38398-1.2	L974A	Neutral	0.197
BRCA1	P38398-1.2	L974C	Neutral	0.14
BRCA1	P38398-1.2	L974D	Neutral	0.296
BRCA1	P38398-1.2	L974E	Neutral	0.164
BRCA1	P38398-1.2	L974F	Neutral	0.059
BRCA1	P38398-1.2	L974G	Pathogenic	0.526
BRCA1	P38398-1.2	L974H	Neutral	0.141
BRCA1	P38398-1.2	L974I	Neutral	0.023
BRCA1	P38398-1.2	L974K	Neutral	0.111
BRCA1	P38398-1.2	L974M	Neutral	0.023
BRCA1	P38398-1.2	L974N	Neutral	0.208
BRCA1	P38398-1.2	L974P	Neutral	0.236
BRCA1	P38398-1.2	L974Q	Neutral	0.11
BRCA1	P38398-1.2	L974R	Neutral	0.142
BRCA1	P38398-1.2	L974S	Neutral	0.235
BRCA1	P38398-1.2	L974T	Neutral	0.121
BRCA1	P38398-1.2	L974V	Neutral	0.049
BRCA1	P38398-1.2	L974W	Neutral	0.194
BRCA1	P38398-1.2	L974Y	Neutral	0.093
BRCA1	P38398-1.2	Q975A	Pathogenic	0.602
BRCA1	P38398-1.2	Q975C	Pathogenic	0.669
BRCA1	P38398-1.2	Q975D	Neutral	0.381
BRCA1	P38398-1.2	Q975E	Neutral	0.167
BRCA1	P38398-1.2	Q975F	Pathogenic	0.631
BRCA1	P38398-1.2	Q975G	Pathogenic	0.769
BRCA1	P38398-1.2	Q975H	Neutral	0.288
BRCA1	P38398-1.2	Q975I	Pathogenic	0.572
BRCA1	P38398-1.2	Q975K	Neutral	0.29
BRCA1	P38398-1.2	Q975L	Neutral	0.482
BRCA1	P38398-1.2	Q975M	Neutral	0.312
BRCA1	P38398-1.2	Q975N	Neutral	0.356
BRCA1	P38398-1.2	Q975P	Neutral	0.474
BRCA1	P38398-1.2	Q975R	Neutral	0.352
BRCA1	P38398-1.2	Q975S	Neutral	0.481
BRCA1	P38398-1.2	Q975T	Neutral	0.459
BRCA1	P38398-1.2	Q975V	Neutral	0.479
BRCA1	P38398-1.2	Q975W	Pathogenic	0.687
BRCA1	P38398-1.2	Q975Y	Neutral	0.489
BRCA1	P38398-1.2	N976A	Pathogenic	0.842
BRCA1	P38398-1.2	N976C	Pathogenic	0.833
BRCA1	P38398-1.2	N976D	Pathogenic	0.516
BRCA1	P38398-1.2	N976E	Pathogenic	0.648
BRCA1	P38398-1.2	N976F	Pathogenic	0.903
BRCA1	P38398-1.2	N976G	Pathogenic	0.798
BRCA1	P38398-1.2	N976H	Pathogenic	0.606
BRCA1	P38398-1.2	N976I	Pathogenic	0.88
BRCA1	P38398-1.2	N976K	Pathogenic	0.765
BRCA1	P38398-1.2	N976L	Pathogenic	0.88
BRCA1	P38398-1.2	N976M	Pathogenic	0.837
BRCA1	P38398-1.2	N976P	Pathogenic	0.761
BRCA1	P38398-1.2	N976Q	Pathogenic	0.671
BRCA1	P38398-1.2	N976R	Pathogenic	0.813
BRCA1	P38398-1.2	N976S	Pathogenic	0.612
BRCA1	P38398-1.2	N976T	Pathogenic	0.591
BRCA1	P38398-1.2	N976V	Pathogenic	0.829
BRCA1	P38398-1.2	N976W	Pathogenic	0.961
BRCA1	P38398-1.2	N976Y	Pathogenic	0.883
BRCA1	P38398-1.2	P977A	Pathogenic	0.737
BRCA1	P38398-1.2	P977C	Pathogenic	0.792
BRCA1	P38398-1.2	P977D	Pathogenic	0.627
BRCA1	P38398-1.2	P977E	Pathogenic	0.716
BRCA1	P38398-1.2	P977F	Pathogenic	0.931
BRCA1	P38398-1.2	P977G	Pathogenic	0.859
BRCA1	P38398-1.2	P977H	Pathogenic	0.818
BRCA1	P38398-1.2	P977I	Pathogenic	0.88
BRCA1	P38398-1.2	P977K	Pathogenic	0.817
BRCA1	P38398-1.2	P977L	Pathogenic	0.88
BRCA1	P38398-1.2	P977M	Pathogenic	0.837
BRCA1	P38398-1.2	P977N	Pathogenic	0.731
BRCA1	P38398-1.2	P977Q	Pathogenic	0.739
BRCA1	P38398-1.2	P977R	Pathogenic	0.895
BRCA1	P38398-1.2	P977S	Pathogenic	0.709
BRCA1	P38398-1.2	P977T	Pathogenic	0.642
BRCA1	P38398-1.2	P977V	Pathogenic	0.771
BRCA1	P38398-1.2	P977W	Pathogenic	0.961
BRCA1	P38398-1.2	P977Y	Pathogenic	0.915
BRCA1	P38398-1.2	Y978A	Neutral	0.454
BRCA1	P38398-1.2	Y978C	Neutral	0.355
BRCA1	P38398-1.2	Y978D	Neutral	0.407
BRCA1	P38398-1.2	Y978E	Neutral	0.243
BRCA1	P38398-1.2	Y978F	Neutral	0.029
BRCA1	P38398-1.2	Y978G	Pathogenic	0.644
BRCA1	P38398-1.2	Y978H	Neutral	0.059
BRCA1	P38398-1.2	Y978I	Neutral	0.14
BRCA1	P38398-1.2	Y978K	Neutral	0.152
BRCA1	P38398-1.2	Y978L	Neutral	0.14
BRCA1	P38398-1.2	Y978M	Neutral	0.141
BRCA1	P38398-1.2	Y978N	Neutral	0.3
BRCA1	P38398-1.2	Y978P	Neutral	0.42
BRCA1	P38398-1.2	Y978Q	Neutral	0.167
BRCA1	P38398-1.2	Y978R	Neutral	0.155
BRCA1	P38398-1.2	Y978S	Neutral	0.419
BRCA1	P38398-1.2	Y978T	Neutral	0.318
BRCA1	P38398-1.2	Y978V	Neutral	0.2
BRCA1	P38398-1.2	Y978W	Neutral	0.057
BRCA1	P38398-1.2	R979A	Neutral	0.013
BRCA1	P38398-1.2	R979C	Neutral	0.017
BRCA1	P38398-1.2	R979D	Neutral	0.011
BRCA1	P38398-1.2	R979E	Neutral	0.004
BRCA1	P38398-1.2	R979F	Neutral	0.006
BRCA1	P38398-1.2	R979G	Neutral	0.028
BRCA1	P38398-1.2	R979H	Neutral	0.003
BRCA1	P38398-1.2	R979I	Neutral	0.007
BRCA1	P38398-1.2	R979K	Neutral	0.001
BRCA1	P38398-1.2	R979L	Neutral	0.005
BRCA1	P38398-1.2	R979M	Neutral	0.004
BRCA1	P38398-1.2	R979N	Neutral	0.005
BRCA1	P38398-1.2	R979P	Neutral	0.011
BRCA1	P38398-1.2	R979Q	Neutral	0.002
BRCA1	P38398-1.2	R979S	Neutral	0.012
BRCA1	P38398-1.2	R979T	Neutral	0.007
BRCA1	P38398-1.2	R979V	Neutral	0.011
BRCA1	P38398-1.2	R979W	Neutral	0.006
BRCA1	P38398-1.2	R979Y	Neutral	0.004
BRCA1	P38398-1.2	I980A	Neutral	0.029
BRCA1	P38398-1.2	I980C	Neutral	0.019
BRCA1	P38398-1.2	I980D	Neutral	0.034
BRCA1	P38398-1.2	I980E	Neutral	0.023
BRCA1	P38398-1.2	I980F	Neutral	0.008
BRCA1	P38398-1.2	I980G	Neutral	0.118
BRCA1	P38398-1.2	I980H	Neutral	0.019
BRCA1	P38398-1.2	I980K	Neutral	0.021
BRCA1	P38398-1.2	I980L	Neutral	0.003
BRCA1	P38398-1.2	I980M	Neutral	0.004
BRCA1	P38398-1.2	I980N	Neutral	0.031
BRCA1	P38398-1.2	I980P	Neutral	0.036
BRCA1	P38398-1.2	I980Q	Neutral	0.021
BRCA1	P38398-1.2	I980R	Neutral	0.028
BRCA1	P38398-1.2	I980S	Neutral	0.036
BRCA1	P38398-1.2	I980T	Neutral	0.016
BRCA1	P38398-1.2	I980V	Neutral	0.003
BRCA1	P38398-1.2	I980W	Neutral	0.04
BRCA1	P38398-1.2	I980Y	Neutral	0.012
BRCA1	P38398-1.2	P981A	Pathogenic	0.568
BRCA1	P38398-1.2	P981C	Pathogenic	0.641
BRCA1	P38398-1.2	P981D	Neutral	0.441
BRCA1	P38398-1.2	P981E	Pathogenic	0.541
BRCA1	P38398-1.2	P981F	Pathogenic	0.863
BRCA1	P38398-1.2	P981G	Pathogenic	0.741
BRCA1	P38398-1.2	P981H	Pathogenic	0.678
BRCA1	P38398-1.2	P981I	Pathogenic	0.774
BRCA1	P38398-1.2	P981K	Pathogenic	0.676
BRCA1	P38398-1.2	P981L	Pathogenic	0.774
BRCA1	P38398-1.2	P981M	Pathogenic	0.707
BRCA1	P38398-1.2	P981N	Pathogenic	0.56
BRCA1	P38398-1.2	P981Q	Pathogenic	0.571
BRCA1	P38398-1.2	P981R	Pathogenic	0.8
BRCA1	P38398-1.2	P981S	Pathogenic	0.533
BRCA1	P38398-1.2	P981T	Neutral	0.457
BRCA1	P38398-1.2	P981V	Pathogenic	0.612
BRCA1	P38398-1.2	P981W	Pathogenic	0.921
BRCA1	P38398-1.2	P981Y	Pathogenic	0.836
BRCA1	P38398-1.2	P982A	Neutral	0.239
BRCA1	P38398-1.2	P982C	Neutral	0.3
BRCA1	P38398-1.2	P982D	Neutral	0.159
BRCA1	P38398-1.2	P982E	Neutral	0.22
BRCA1	P38398-1.2	P982F	Pathogenic	0.601
BRCA1	P38398-1.2	P982G	Neutral	0.407
BRCA1	P38398-1.2	P982H	Neutral	0.335
BRCA1	P38398-1.2	P982I	Neutral	0.451
BRCA1	P38398-1.2	P982K	Neutral	0.333
BRCA1	P38398-1.2	P982L	Neutral	0.451
BRCA1	P38398-1.2	P982M	Neutral	0.366
BRCA1	P38398-1.2	P982N	Neutral	0.234
BRCA1	P38398-1.2	P982Q	Neutral	0.241
BRCA1	P38398-1.2	P982R	Neutral	0.49
BRCA1	P38398-1.2	P982S	Neutral	0.215
BRCA1	P38398-1.2	P982T	Neutral	0.168
BRCA1	P38398-1.2	P982V	Neutral	0.274
BRCA1	P38398-1.2	P982W	Pathogenic	0.736
BRCA1	P38398-1.2	P982Y	Pathogenic	0.549
BRCA1	P38398-1.2	L983A	Neutral	0.114
BRCA1	P38398-1.2	L983C	Neutral	0.079
BRCA1	P38398-1.2	L983D	Neutral	0.181
BRCA1	P38398-1.2	L983E	Neutral	0.094
BRCA1	P38398-1.2	L983F	Neutral	0.032
BRCA1	P38398-1.2	L983G	Neutral	0.368
BRCA1	P38398-1.2	L983H	Neutral	0.079
BRCA1	P38398-1.2	L983I	Neutral	0.012
BRCA1	P38398-1.2	L983K	Neutral	0.061
BRCA1	P38398-1.2	L983M	Neutral	0.012
BRCA1	P38398-1.2	L983N	Neutral	0.121
BRCA1	P38398-1.2	L983P	Neutral	0.139
BRCA1	P38398-1.2	L983Q	Neutral	0.061
BRCA1	P38398-1.2	L983R	Neutral	0.08
BRCA1	P38398-1.2	L983S	Neutral	0.139
BRCA1	P38398-1.2	L983T	Neutral	0.068
BRCA1	P38398-1.2	L983V	Neutral	0.027
BRCA1	P38398-1.2	L983W	Neutral	0.112
BRCA1	P38398-1.2	L983Y	Neutral	0.051
BRCA1	P38398-1.2	F984A	Pathogenic	0.765
BRCA1	P38398-1.2	F984C	Pathogenic	0.684
BRCA1	P38398-1.2	F984D	Pathogenic	0.729
BRCA1	P38398-1.2	F984E	Pathogenic	0.644
BRCA1	P38398-1.2	F984G	Pathogenic	0.877
BRCA1	P38398-1.2	F984H	Neutral	0.421
BRCA1	P38398-1.2	F984I	Neutral	0.313
BRCA1	P38398-1.2	F984K	Pathogenic	0.502
BRCA1	P38398-1.2	F984L	Neutral	0.313
BRCA1	P38398-1.2	F984M	Neutral	0.311
BRCA1	P38398-1.2	F984N	Pathogenic	0.707
BRCA1	P38398-1.2	F984P	Pathogenic	0.803
BRCA1	P38398-1.2	F984Q	Pathogenic	0.62
BRCA1	P38398-1.2	F984R	Pathogenic	0.574
BRCA1	P38398-1.2	F984S	Pathogenic	0.739
BRCA1	P38398-1.2	F984T	Pathogenic	0.646
BRCA1	P38398-1.2	F984V	Neutral	0.497
BRCA1	P38398-1.2	F984W	Neutral	0.314
BRCA1	P38398-1.2	F984Y	Neutral	0.119
BRCA1	P38398-1.2	P985A	Pathogenic	0.754
BRCA1	P38398-1.2	P985C	Pathogenic	0.807
BRCA1	P38398-1.2	P985D	Pathogenic	0.648
BRCA1	P38398-1.2	P985E	Pathogenic	0.734
BRCA1	P38398-1.2	P985F	Pathogenic	0.936
BRCA1	P38398-1.2	P985G	Pathogenic	0.87
BRCA1	P38398-1.2	P985H	Pathogenic	0.831
BRCA1	P38398-1.2	P985I	Pathogenic	0.889
BRCA1	P38398-1.2	P985K	Pathogenic	0.83
BRCA1	P38398-1.2	P985L	Pathogenic	0.889
BRCA1	P38398-1.2	P985M	Pathogenic	0.849
BRCA1	P38398-1.2	P985N	Pathogenic	0.748
BRCA1	P38398-1.2	P985Q	Pathogenic	0.757
BRCA1	P38398-1.2	P985R	Pathogenic	0.904
BRCA1	P38398-1.2	P985S	Pathogenic	0.727
BRCA1	P38398-1.2	P985T	Pathogenic	0.663
BRCA1	P38398-1.2	P985V	Pathogenic	0.787
BRCA1	P38398-1.2	P985W	Pathogenic	0.965
BRCA1	P38398-1.2	P985Y	Pathogenic	0.922
BRCA1	P38398-1.2	I986A	Neutral	0.166
BRCA1	P38398-1.2	I986C	Neutral	0.117
BRCA1	P38398-1.2	I986D	Neutral	0.191
BRCA1	P38398-1.2	I986E	Neutral	0.137
BRCA1	P38398-1.2	I986F	Neutral	0.049
BRCA1	P38398-1.2	I986G	Neutral	0.473
BRCA1	P38398-1.2	I986H	Neutral	0.117
BRCA1	P38398-1.2	I986K	Neutral	0.126
BRCA1	P38398-1.2	I986L	Neutral	0.019
BRCA1	P38398-1.2	I986M	Neutral	0.027
BRCA1	P38398-1.2	I986N	Neutral	0.175
BRCA1	P38398-1.2	I986P	Neutral	0.199
BRCA1	P38398-1.2	I986Q	Neutral	0.125
BRCA1	P38398-1.2	I986R	Neutral	0.162
BRCA1	P38398-1.2	I986S	Neutral	0.199
BRCA1	P38398-1.2	I986T	Neutral	0.1
BRCA1	P38398-1.2	I986V	Neutral	0.02
BRCA1	P38398-1.2	I986W	Neutral	0.22
BRCA1	P38398-1.2	I986Y	Neutral	0.076
BRCA1	P38398-1.2	K987A	Neutral	0.15
BRCA1	P38398-1.2	K987C	Neutral	0.192
BRCA1	P38398-1.2	K987D	Neutral	0.096
BRCA1	P38398-1.2	K987E	Neutral	0.033
BRCA1	P38398-1.2	K987F	Neutral	0.073
BRCA1	P38398-1.2	K987G	Neutral	0.281
BRCA1	P38398-1.2	K987H	Neutral	0.054
BRCA1	P38398-1.2	K987I	Neutral	0.091
BRCA1	P38398-1.2	K987L	Neutral	0.065
BRCA1	P38398-1.2	K987M	Neutral	0.047
BRCA1	P38398-1.2	K987N	Neutral	0.062
BRCA1	P38398-1.2	K987P	Neutral	0.095
BRCA1	P38398-1.2	K987Q	Neutral	0.03
BRCA1	P38398-1.2	K987R	Neutral	0.018
BRCA1	P38398-1.2	K987S	Neutral	0.098
BRCA1	P38398-1.2	K987T	Neutral	0.09
BRCA1	P38398-1.2	K987V	Neutral	0.097
BRCA1	P38398-1.2	K987W	Neutral	0.127
BRCA1	P38398-1.2	K987Y	Neutral	0.06
BRCA1	P38398-1.2	S988A	Neutral	0.093
BRCA1	P38398-1.2	S988C	Neutral	0.196
BRCA1	P38398-1.2	S988D	Neutral	0.16
BRCA1	P38398-1.2	S988E	Neutral	0.221
BRCA1	P38398-1.2	S988F	Pathogenic	0.506
BRCA1	P38398-1.2	S988G	Neutral	0.184
BRCA1	P38398-1.2	S988H	Neutral	0.335
BRCA1	P38398-1.2	S988I	Neutral	0.445
BRCA1	P38398-1.2	S988K	Neutral	0.335
BRCA1	P38398-1.2	S988L	Neutral	0.446
BRCA1	P38398-1.2	S988M	Neutral	0.36
BRCA1	P38398-1.2	S988N	Neutral	0.129
BRCA1	P38398-1.2	S988P	Neutral	0.211
BRCA1	P38398-1.2	S988Q	Neutral	0.243
BRCA1	P38398-1.2	S988R	Neutral	0.491
BRCA1	P38398-1.2	S988T	Neutral	0.122
BRCA1	P38398-1.2	S988V	Neutral	0.347
BRCA1	P38398-1.2	S988W	Pathogenic	0.731
BRCA1	P38398-1.2	S988Y	Pathogenic	0.543
BRCA1	P38398-1.2	F989A	Neutral	0.087
BRCA1	P38398-1.2	F989C	Neutral	0.06
BRCA1	P38398-1.2	F989D	Neutral	0.073
BRCA1	P38398-1.2	F989E	Neutral	0.05
BRCA1	P38398-1.2	F989G	Neutral	0.173
BRCA1	P38398-1.2	F989H	Neutral	0.021
BRCA1	P38398-1.2	F989I	Neutral	0.013
BRCA1	P38398-1.2	F989K	Neutral	0.029
BRCA1	P38398-1.2	F989L	Neutral	0.013
BRCA1	P38398-1.2	F989M	Neutral	0.013
BRCA1	P38398-1.2	F989N	Neutral	0.066
BRCA1	P38398-1.2	F989P	Neutral	0.107
BRCA1	P38398-1.2	F989Q	Neutral	0.046
BRCA1	P38398-1.2	F989R	Neutral	0.038
BRCA1	P38398-1.2	F989S	Neutral	0.077
BRCA1	P38398-1.2	F989T	Neutral	0.051
BRCA1	P38398-1.2	F989V	Neutral	0.028
BRCA1	P38398-1.2	F989W	Neutral	0.013
BRCA1	P38398-1.2	F989Y	Neutral	0.004
BRCA1	P38398-1.2	V990A	Neutral	0.349
BRCA1	P38398-1.2	V990C	Neutral	0.339
BRCA1	P38398-1.2	V990D	Neutral	0.479
BRCA1	P38398-1.2	V990E	Neutral	0.339
BRCA1	P38398-1.2	V990F	Neutral	0.394
BRCA1	P38398-1.2	V990G	Pathogenic	0.708
BRCA1	P38398-1.2	V990H	Neutral	0.478
BRCA1	P38398-1.2	V990I	Neutral	0.106
BRCA1	P38398-1.2	V990K	Neutral	0.476
BRCA1	P38398-1.2	V990L	Neutral	0.198
BRCA1	P38398-1.2	V990M	Neutral	0.199
BRCA1	P38398-1.2	V990N	Neutral	0.452
BRCA1	P38398-1.2	V990P	Neutral	0.402
BRCA1	P38398-1.2	V990Q	Neutral	0.366
BRCA1	P38398-1.2	V990R	Pathogenic	0.635
BRCA1	P38398-1.2	V990S	Neutral	0.491
BRCA1	P38398-1.2	V990T	Neutral	0.231
BRCA1	P38398-1.2	V990W	Pathogenic	0.713
BRCA1	P38398-1.2	V990Y	Neutral	0.428
BRCA1	P38398-1.2	K991A	Pathogenic	0.842
BRCA1	P38398-1.2	K991C	Pathogenic	0.877
BRCA1	P38398-1.2	K991D	Pathogenic	0.762
BRCA1	P38398-1.2	K991E	Pathogenic	0.508
BRCA1	P38398-1.2	K991F	Pathogenic	0.703
BRCA1	P38398-1.2	K991G	Pathogenic	0.922
BRCA1	P38398-1.2	K991H	Pathogenic	0.633
BRCA1	P38398-1.2	K991I	Pathogenic	0.752
BRCA1	P38398-1.2	K991L	Pathogenic	0.678
BRCA1	P38398-1.2	K991M	Pathogenic	0.596
BRCA1	P38398-1.2	K991N	Pathogenic	0.664
BRCA1	P38398-1.2	K991P	Pathogenic	0.76
BRCA1	P38398-1.2	K991Q	Neutral	0.478
BRCA1	P38398-1.2	K991R	Neutral	0.351
BRCA1	P38398-1.2	K991S	Pathogenic	0.765
BRCA1	P38398-1.2	K991T	Pathogenic	0.75
BRCA1	P38398-1.2	K991V	Pathogenic	0.764
BRCA1	P38398-1.2	K991W	Pathogenic	0.814
BRCA1	P38398-1.2	K991Y	Pathogenic	0.657
BRCA1	P38398-1.2	T992A	Neutral	0.261
BRCA1	P38398-1.2	T992C	Neutral	0.248
BRCA1	P38398-1.2	T992D	Neutral	0.227
BRCA1	P38398-1.2	T992E	Neutral	0.286
BRCA1	P38398-1.2	T992F	Pathogenic	0.504
BRCA1	P38398-1.2	T992G	Pathogenic	0.527
BRCA1	P38398-1.2	T992H	Neutral	0.417
BRCA1	P38398-1.2	T992I	Neutral	0.356
BRCA1	P38398-1.2	T992K	Neutral	0.415
BRCA1	P38398-1.2	T992L	Neutral	0.356
BRCA1	P38398-1.2	T992M	Neutral	0.358
BRCA1	P38398-1.2	T992N	Neutral	0.173
BRCA1	P38398-1.2	T992P	Neutral	0.232
BRCA1	P38398-1.2	T992Q	Neutral	0.311
BRCA1	P38398-1.2	T992R	Neutral	0.486
BRCA1	P38398-1.2	T992S	Neutral	0.176
BRCA1	P38398-1.2	T992V	Neutral	0.203
BRCA1	P38398-1.2	T992W	Pathogenic	0.652
BRCA1	P38398-1.2	T992Y	Pathogenic	0.541
BRCA1	P38398-1.2	K993A	Neutral	0.002
BRCA1	P38398-1.2	K993C	Neutral	0.002
BRCA1	P38398-1.2	K993D	Neutral	0.001
BRCA1	P38398-1.2	K993E	Neutral	0.0
BRCA1	P38398-1.2	K993F	Neutral	0.001
BRCA1	P38398-1.2	K993G	Neutral	0.004
BRCA1	P38398-1.2	K993H	Neutral	0.001
BRCA1	P38398-1.2	K993I	Neutral	0.001
BRCA1	P38398-1.2	K993L	Neutral	0.001
BRCA1	P38398-1.2	K993M	Neutral	0.0
BRCA1	P38398-1.2	K993N	Neutral	0.001
BRCA1	P38398-1.2	K993P	Neutral	0.001
BRCA1	P38398-1.2	K993Q	Neutral	0.0
BRCA1	P38398-1.2	K993R	Neutral	0.0
BRCA1	P38398-1.2	K993S	Neutral	0.001
BRCA1	P38398-1.2	K993T	Neutral	0.001
BRCA1	P38398-1.2	K993V	Neutral	0.001
BRCA1	P38398-1.2	K993W	Neutral	0.001
BRCA1	P38398-1.2	K993Y	Neutral	0.001
BRCA1	P38398-1.2	C994A	Neutral	0.082
BRCA1	P38398-1.2	C994D	Neutral	0.16
BRCA1	P38398-1.2	C994E	Neutral	0.291
BRCA1	P38398-1.2	C994F	Neutral	0.264
BRCA1	P38398-1.2	C994G	Neutral	0.287
BRCA1	P38398-1.2	C994H	Neutral	0.261
BRCA1	P38398-1.2	C994I	Neutral	0.163
BRCA1	P38398-1.2	C994K	Neutral	0.336
BRCA1	P38398-1.2	C994L	Neutral	0.164
BRCA1	P38398-1.2	C994M	Neutral	0.165
BRCA1	P38398-1.2	C994N	Neutral	0.176
BRCA1	P38398-1.2	C994P	Neutral	0.161
BRCA1	P38398-1.2	C994Q	Neutral	0.243
BRCA1	P38398-1.2	C994R	Neutral	0.403
BRCA1	P38398-1.2	C994S	Neutral	0.1
BRCA1	P38398-1.2	C994T	Neutral	0.09
BRCA1	P38398-1.2	C994V	Neutral	0.115
BRCA1	P38398-1.2	C994W	Neutral	0.399
BRCA1	P38398-1.2	C994Y	Neutral	0.294
BRCA1	P38398-1.2	K995A	Neutral	0.179
BRCA1	P38398-1.2	K995C	Neutral	0.226
BRCA1	P38398-1.2	K995D	Neutral	0.115
BRCA1	P38398-1.2	K995E	Neutral	0.04
BRCA1	P38398-1.2	K995F	Neutral	0.088
BRCA1	P38398-1.2	K995G	Neutral	0.325
BRCA1	P38398-1.2	K995H	Neutral	0.066
BRCA1	P38398-1.2	K995I	Neutral	0.11
BRCA1	P38398-1.2	K995L	Neutral	0.079
BRCA1	P38398-1.2	K995M	Neutral	0.057
BRCA1	P38398-1.2	K995N	Neutral	0.075
BRCA1	P38398-1.2	K995P	Neutral	0.115
BRCA1	P38398-1.2	K995Q	Neutral	0.036
BRCA1	P38398-1.2	K995R	Neutral	0.022
BRCA1	P38398-1.2	K995S	Neutral	0.118
BRCA1	P38398-1.2	K995T	Neutral	0.109
BRCA1	P38398-1.2	K995V	Neutral	0.117
BRCA1	P38398-1.2	K995W	Neutral	0.152
BRCA1	P38398-1.2	K995Y	Neutral	0.072
BRCA1	P38398-1.2	K996A	Pathogenic	0.55
BRCA1	P38398-1.2	K996C	Pathogenic	0.621
BRCA1	P38398-1.2	K996D	Neutral	0.423
BRCA1	P38398-1.2	K996E	Neutral	0.191
BRCA1	P38398-1.2	K996F	Neutral	0.352
BRCA1	P38398-1.2	K996G	Pathogenic	0.73
BRCA1	P38398-1.2	K996H	Neutral	0.283
BRCA1	P38398-1.2	K996I	Neutral	0.41
BRCA1	P38398-1.2	K996L	Neutral	0.326
BRCA1	P38398-1.2	K996M	Neutral	0.253
BRCA1	P38398-1.2	K996N	Neutral	0.312
BRCA1	P38398-1.2	K996P	Neutral	0.421
BRCA1	P38398-1.2	K996Q	Neutral	0.174
BRCA1	P38398-1.2	K996R	Neutral	0.11
BRCA1	P38398-1.2	K996S	Neutral	0.428
BRCA1	P38398-1.2	K996T	Neutral	0.407
BRCA1	P38398-1.2	K996V	Neutral	0.427
BRCA1	P38398-1.2	K996W	Pathogenic	0.501
BRCA1	P38398-1.2	K996Y	Neutral	0.305
BRCA1	P38398-1.2	N997A	Neutral	0.301
BRCA1	P38398-1.2	N997C	Neutral	0.286
BRCA1	P38398-1.2	N997D	Neutral	0.079
BRCA1	P38398-1.2	N997E	Neutral	0.129
BRCA1	P38398-1.2	N997F	Neutral	0.429
BRCA1	P38398-1.2	N997G	Neutral	0.242
BRCA1	P38398-1.2	N997H	Neutral	0.11
BRCA1	P38398-1.2	N997I	Neutral	0.371
BRCA1	P38398-1.2	N997K	Neutral	0.208
BRCA1	P38398-1.2	N997L	Neutral	0.371
BRCA1	P38398-1.2	N997M	Neutral	0.293
BRCA1	P38398-1.2	N997P	Neutral	0.204
BRCA1	P38398-1.2	N997Q	Neutral	0.141
BRCA1	P38398-1.2	N997R	Neutral	0.259
BRCA1	P38398-1.2	N997S	Neutral	0.113
BRCA1	P38398-1.2	N997T	Neutral	0.105
BRCA1	P38398-1.2	N997V	Neutral	0.281
BRCA1	P38398-1.2	N997W	Pathogenic	0.666
BRCA1	P38398-1.2	N997Y	Neutral	0.378
BRCA1	P38398-1.2	L998A	Pathogenic	0.713
BRCA1	P38398-1.2	L998C	Pathogenic	0.623
BRCA1	P38398-1.2	L998D	Pathogenic	0.81
BRCA1	P38398-1.2	L998E	Pathogenic	0.666
BRCA1	P38398-1.2	L998F	Neutral	0.389
BRCA1	P38398-1.2	L998G	Pathogenic	0.918
BRCA1	P38398-1.2	L998H	Pathogenic	0.623
BRCA1	P38398-1.2	L998I	Neutral	0.194
BRCA1	P38398-1.2	L998K	Pathogenic	0.557
BRCA1	P38398-1.2	L998M	Neutral	0.193
BRCA1	P38398-1.2	L998N	Pathogenic	0.727
BRCA1	P38398-1.2	L998P	Pathogenic	0.757
BRCA1	P38398-1.2	L998Q	Pathogenic	0.555
BRCA1	P38398-1.2	L998R	Pathogenic	0.626
BRCA1	P38398-1.2	L998S	Pathogenic	0.757
BRCA1	P38398-1.2	L998T	Pathogenic	0.582
BRCA1	P38398-1.2	L998V	Neutral	0.344
BRCA1	P38398-1.2	L998W	Pathogenic	0.709
BRCA1	P38398-1.2	L998Y	Pathogenic	0.509
BRCA1	P38398-1.2	L999A	Neutral	0.061
BRCA1	P38398-1.2	L999C	Neutral	0.041
BRCA1	P38398-1.2	L999D	Neutral	0.1
BRCA1	P38398-1.2	L999E	Neutral	0.049
BRCA1	P38398-1.2	L999F	Neutral	0.016
BRCA1	P38398-1.2	L999G	Neutral	0.227
BRCA1	P38398-1.2	L999H	Neutral	0.041
BRCA1	P38398-1.2	L999I	Neutral	0.006
BRCA1	P38398-1.2	L999K	Neutral	0.032
BRCA1	P38398-1.2	L999M	Neutral	0.006
BRCA1	P38398-1.2	L999N	Neutral	0.065
BRCA1	P38398-1.2	L999P	Neutral	0.075
BRCA1	P38398-1.2	L999Q	Neutral	0.032
BRCA1	P38398-1.2	L999R	Neutral	0.042
BRCA1	P38398-1.2	L999S	Neutral	0.075
BRCA1	P38398-1.2	L999T	Neutral	0.035
BRCA1	P38398-1.2	L999V	Neutral	0.014
BRCA1	P38398-1.2	L999W	Neutral	0.06
BRCA1	P38398-1.2	L999Y	Neutral	0.026
BRCA1	P38398-1.2	E1000A	Pathogenic	0.566
BRCA1	P38398-1.2	E1000C	Pathogenic	0.715
BRCA1	P38398-1.2	E1000D	Neutral	0.207
BRCA1	P38398-1.2	E1000F	Pathogenic	0.648
BRCA1	P38398-1.2	E1000G	Pathogenic	0.742
BRCA1	P38398-1.2	E1000H	Neutral	0.304
BRCA1	P38398-1.2	E1000I	Pathogenic	0.59
BRCA1	P38398-1.2	E1000K	Neutral	0.308
BRCA1	P38398-1.2	E1000L	Pathogenic	0.59
BRCA1	P38398-1.2	E1000M	Pathogenic	0.503
BRCA1	P38398-1.2	E1000N	Neutral	0.326
BRCA1	P38398-1.2	E1000P	Neutral	0.437
BRCA1	P38398-1.2	E1000Q	Neutral	0.163
BRCA1	P38398-1.2	E1000R	Neutral	0.461
BRCA1	P38398-1.2	E1000S	Neutral	0.444
BRCA1	P38398-1.2	E1000T	Neutral	0.423
BRCA1	P38398-1.2	E1000V	Neutral	0.442
BRCA1	P38398-1.2	E1000W	Pathogenic	0.772
BRCA1	P38398-1.2	E1000Y	Pathogenic	0.597
BRCA1	P38398-1.2	E1001A	Neutral	0.459
BRCA1	P38398-1.2	E1001C	Pathogenic	0.621
BRCA1	P38398-1.2	E1001D	Neutral	0.145
BRCA1	P38398-1.2	E1001F	Pathogenic	0.545
BRCA1	P38398-1.2	E1001G	Pathogenic	0.652
BRCA1	P38398-1.2	E1001H	Neutral	0.222
BRCA1	P38398-1.2	E1001I	Neutral	0.484
BRCA1	P38398-1.2	E1001K	Neutral	0.225
BRCA1	P38398-1.2	E1001L	Neutral	0.485
BRCA1	P38398-1.2	E1001M	Neutral	0.397
BRCA1	P38398-1.2	E1001N	Neutral	0.24
BRCA1	P38398-1.2	E1001P	Neutral	0.336
BRCA1	P38398-1.2	E1001Q	Neutral	0.112
BRCA1	P38398-1.2	E1001R	Neutral	0.358
BRCA1	P38398-1.2	E1001S	Neutral	0.342
BRCA1	P38398-1.2	E1001T	Neutral	0.323
BRCA1	P38398-1.2	E1001V	Neutral	0.341
BRCA1	P38398-1.2	E1001W	Pathogenic	0.689
BRCA1	P38398-1.2	E1001Y	Neutral	0.492
BRCA1	P38398-1.2	N1002A	Neutral	0.004
BRCA1	P38398-1.2	N1002C	Neutral	0.004
BRCA1	P38398-1.2	N1002D	Neutral	0.001
BRCA1	P38398-1.2	N1002E	Neutral	0.002
BRCA1	P38398-1.2	N1002F	Neutral	0.008
BRCA1	P38398-1.2	N1002G	Neutral	0.003
BRCA1	P38398-1.2	N1002H	Neutral	0.001
BRCA1	P38398-1.2	N1002I	Neutral	0.006
BRCA1	P38398-1.2	N1002K	Neutral	0.003
BRCA1	P38398-1.2	N1002L	Neutral	0.006
BRCA1	P38398-1.2	N1002M	Neutral	0.004
BRCA1	P38398-1.2	N1002P	Neutral	0.003
BRCA1	P38398-1.2	N1002Q	Neutral	0.002
BRCA1	P38398-1.2	N1002R	Neutral	0.004
BRCA1	P38398-1.2	N1002S	Neutral	0.001
BRCA1	P38398-1.2	N1002T	Neutral	0.001
BRCA1	P38398-1.2	N1002V	Neutral	0.004
BRCA1	P38398-1.2	N1002W	Neutral	0.02
BRCA1	P38398-1.2	N1002Y	Neutral	0.006
BRCA1	P38398-1.2	F1003A	Pathogenic	0.509
BRCA1	P38398-1.2	F1003C	Neutral	0.408
BRCA1	P38398-1.2	F1003D	Neutral	0.462
BRCA1	P38398-1.2	F1003E	Neutral	0.366
BRCA1	P38398-1.2	F1003G	Pathogenic	0.694
BRCA1	P38398-1.2	F1003H	Neutral	0.188
BRCA1	P38398-1.2	F1003I	Neutral	0.127
BRCA1	P38398-1.2	F1003K	Neutral	0.243
BRCA1	P38398-1.2	F1003L	Neutral	0.127
BRCA1	P38398-1.2	F1003M	Neutral	0.126
BRCA1	P38398-1.2	F1003N	Neutral	0.435
BRCA1	P38398-1.2	F1003P	Pathogenic	0.565
BRCA1	P38398-1.2	F1003Q	Neutral	0.342
BRCA1	P38398-1.2	F1003R	Neutral	0.3
BRCA1	P38398-1.2	F1003S	Neutral	0.474
BRCA1	P38398-1.2	F1003T	Neutral	0.368
BRCA1	P38398-1.2	F1003V	Neutral	0.24
BRCA1	P38398-1.2	F1003W	Neutral	0.127
BRCA1	P38398-1.2	F1003Y	Neutral	0.041
BRCA1	P38398-1.2	E1004A	Pathogenic	0.642
BRCA1	P38398-1.2	E1004C	Pathogenic	0.776
BRCA1	P38398-1.2	E1004D	Neutral	0.264
BRCA1	P38398-1.2	E1004F	Pathogenic	0.717
BRCA1	P38398-1.2	E1004G	Pathogenic	0.798
BRCA1	P38398-1.2	E1004H	Neutral	0.375
BRCA1	P38398-1.2	E1004I	Pathogenic	0.664
BRCA1	P38398-1.2	E1004K	Neutral	0.38
BRCA1	P38398-1.2	E1004L	Pathogenic	0.665
BRCA1	P38398-1.2	E1004M	Pathogenic	0.582
BRCA1	P38398-1.2	E1004N	Neutral	0.4
BRCA1	P38398-1.2	E1004P	Pathogenic	0.516
BRCA1	P38398-1.2	E1004Q	Neutral	0.211
BRCA1	P38398-1.2	E1004R	Pathogenic	0.541
BRCA1	P38398-1.2	E1004S	Pathogenic	0.523
BRCA1	P38398-1.2	E1004T	Pathogenic	0.502
BRCA1	P38398-1.2	E1004V	Pathogenic	0.522
BRCA1	P38398-1.2	E1004W	Pathogenic	0.824
BRCA1	P38398-1.2	E1004Y	Pathogenic	0.671
BRCA1	P38398-1.2	E1005A	Neutral	0.056
BRCA1	P38398-1.2	E1005C	Neutral	0.103
BRCA1	P38398-1.2	E1005D	Neutral	0.012
BRCA1	P38398-1.2	E1005F	Neutral	0.078
BRCA1	P38398-1.2	E1005G	Neutral	0.117
BRCA1	P38398-1.2	E1005H	Neutral	0.02
BRCA1	P38398-1.2	E1005I	Neutral	0.062
BRCA1	P38398-1.2	E1005K	Neutral	0.02
BRCA1	P38398-1.2	E1005L	Neutral	0.062
BRCA1	P38398-1.2	E1005M	Neutral	0.044
BRCA1	P38398-1.2	E1005N	Neutral	0.022
BRCA1	P38398-1.2	E1005P	Neutral	0.034
BRCA1	P38398-1.2	E1005Q	Neutral	0.009
BRCA1	P38398-1.2	E1005R	Neutral	0.038
BRCA1	P38398-1.2	E1005S	Neutral	0.035
BRCA1	P38398-1.2	E1005T	Neutral	0.032
BRCA1	P38398-1.2	E1005V	Neutral	0.035
BRCA1	P38398-1.2	E1005W	Neutral	0.135
BRCA1	P38398-1.2	E1005Y	Neutral	0.064
BRCA1	P38398-1.2	H1006A	Neutral	0.082
BRCA1	P38398-1.2	H1006C	Neutral	0.076
BRCA1	P38398-1.2	H1006D	Neutral	0.034
BRCA1	P38398-1.2	H1006E	Neutral	0.016
BRCA1	P38398-1.2	H1006F	Neutral	0.027
BRCA1	P38398-1.2	H1006G	Neutral	0.119
BRCA1	P38398-1.2	H1006I	Neutral	0.044
BRCA1	P38398-1.2	H1006K	Neutral	0.028
BRCA1	P38398-1.2	H1006L	Neutral	0.044
BRCA1	P38398-1.2	H1006M	Neutral	0.031
BRCA1	P38398-1.2	H1006N	Neutral	0.015
BRCA1	P38398-1.2	H1006P	Neutral	0.05
BRCA1	P38398-1.2	H1006Q	Neutral	0.015
BRCA1	P38398-1.2	H1006R	Neutral	0.026
BRCA1	P38398-1.2	H1006S	Neutral	0.051
BRCA1	P38398-1.2	H1006T	Neutral	0.048
BRCA1	P38398-1.2	H1006V	Neutral	0.051
BRCA1	P38398-1.2	H1006W	Neutral	0.07
BRCA1	P38398-1.2	H1006Y	Neutral	0.011
BRCA1	P38398-1.2	S1007A	Neutral	0.008
BRCA1	P38398-1.2	S1007C	Neutral	0.02
BRCA1	P38398-1.2	S1007D	Neutral	0.015
BRCA1	P38398-1.2	S1007E	Neutral	0.023
BRCA1	P38398-1.2	S1007F	Neutral	0.077
BRCA1	P38398-1.2	S1007G	Neutral	0.018
BRCA1	P38398-1.2	S1007H	Neutral	0.04
BRCA1	P38398-1.2	S1007I	Neutral	0.062
BRCA1	P38398-1.2	S1007K	Neutral	0.04
BRCA1	P38398-1.2	S1007L	Neutral	0.062
BRCA1	P38398-1.2	S1007M	Neutral	0.044
BRCA1	P38398-1.2	S1007N	Neutral	0.012
BRCA1	P38398-1.2	S1007P	Neutral	0.021
BRCA1	P38398-1.2	S1007Q	Neutral	0.026
BRCA1	P38398-1.2	S1007R	Neutral	0.073
BRCA1	P38398-1.2	S1007T	Neutral	0.011
BRCA1	P38398-1.2	S1007V	Neutral	0.042
BRCA1	P38398-1.2	S1007W	Neutral	0.182
BRCA1	P38398-1.2	S1007Y	Neutral	0.089
BRCA1	P38398-1.2	M1008A	Neutral	0.005
BRCA1	P38398-1.2	M1008C	Neutral	0.003
BRCA1	P38398-1.2	M1008D	Neutral	0.006
BRCA1	P38398-1.2	M1008E	Neutral	0.003
BRCA1	P38398-1.2	M1008F	Neutral	0.001
BRCA1	P38398-1.2	M1008G	Neutral	0.015
BRCA1	P38398-1.2	M1008H	Neutral	0.002
BRCA1	P38398-1.2	M1008I	Neutral	0.001
BRCA1	P38398-1.2	M1008K	Neutral	0.002
BRCA1	P38398-1.2	M1008L	Neutral	0.0
BRCA1	P38398-1.2	M1008N	Neutral	0.004
BRCA1	P38398-1.2	M1008P	Neutral	0.004
BRCA1	P38398-1.2	M1008Q	Neutral	0.001
BRCA1	P38398-1.2	M1008R	Neutral	0.002
BRCA1	P38398-1.2	M1008S	Neutral	0.004
BRCA1	P38398-1.2	M1008T	Neutral	0.003
BRCA1	P38398-1.2	M1008V	Neutral	0.001
BRCA1	P38398-1.2	M1008W	Neutral	0.003
BRCA1	P38398-1.2	M1008Y	Neutral	0.002
BRCA1	P38398-1.2	S1009A	Pathogenic	0.628
BRCA1	P38398-1.2	S1009C	Pathogenic	0.801
BRCA1	P38398-1.2	S1009D	Pathogenic	0.759
BRCA1	P38398-1.2	S1009E	Pathogenic	0.825
BRCA1	P38398-1.2	S1009F	Pathogenic	0.944
BRCA1	P38398-1.2	S1009G	Pathogenic	0.788
BRCA1	P38398-1.2	S1009H	Pathogenic	0.893
BRCA1	P38398-1.2	S1009I	Pathogenic	0.93
BRCA1	P38398-1.2	S1009K	Pathogenic	0.893
BRCA1	P38398-1.2	S1009L	Pathogenic	0.93
BRCA1	P38398-1.2	S1009M	Pathogenic	0.903
BRCA1	P38398-1.2	S1009N	Pathogenic	0.71
BRCA1	P38398-1.2	S1009P	Pathogenic	0.816
BRCA1	P38398-1.2	S1009Q	Pathogenic	0.841
BRCA1	P38398-1.2	S1009R	Pathogenic	0.941
BRCA1	P38398-1.2	S1009T	Pathogenic	0.697
BRCA1	P38398-1.2	S1009V	Pathogenic	0.898
BRCA1	P38398-1.2	S1009W	Pathogenic	0.978
BRCA1	P38398-1.2	S1009Y	Pathogenic	0.952
BRCA1	P38398-1.2	P1010A	Neutral	0.251
BRCA1	P38398-1.2	P1010C	Neutral	0.313
BRCA1	P38398-1.2	P1010D	Neutral	0.168
BRCA1	P38398-1.2	P1010E	Neutral	0.231
BRCA1	P38398-1.2	P1010F	Pathogenic	0.616
BRCA1	P38398-1.2	P1010G	Neutral	0.422
BRCA1	P38398-1.2	P1010H	Neutral	0.349
BRCA1	P38398-1.2	P1010I	Neutral	0.467
BRCA1	P38398-1.2	P1010K	Neutral	0.348
BRCA1	P38398-1.2	P1010L	Neutral	0.467
BRCA1	P38398-1.2	P1010M	Neutral	0.381
BRCA1	P38398-1.2	P1010N	Neutral	0.245
BRCA1	P38398-1.2	P1010Q	Neutral	0.253
BRCA1	P38398-1.2	P1010R	Pathogenic	0.506
BRCA1	P38398-1.2	P1010S	Neutral	0.226
BRCA1	P38398-1.2	P1010T	Neutral	0.177
BRCA1	P38398-1.2	P1010V	Neutral	0.287
BRCA1	P38398-1.2	P1010W	Pathogenic	0.748
BRCA1	P38398-1.2	P1010Y	Pathogenic	0.565
BRCA1	P38398-1.2	E1011A	Pathogenic	0.652
BRCA1	P38398-1.2	E1011C	Pathogenic	0.784
BRCA1	P38398-1.2	E1011D	Neutral	0.273
BRCA1	P38398-1.2	E1011F	Pathogenic	0.726
BRCA1	P38398-1.2	E1011G	Pathogenic	0.806
BRCA1	P38398-1.2	E1011H	Neutral	0.386
BRCA1	P38398-1.2	E1011I	Pathogenic	0.675
BRCA1	P38398-1.2	E1011K	Neutral	0.391
BRCA1	P38398-1.2	E1011L	Pathogenic	0.675
BRCA1	P38398-1.2	E1011M	Pathogenic	0.593
BRCA1	P38398-1.2	E1011N	Neutral	0.411
BRCA1	P38398-1.2	E1011P	Pathogenic	0.528
BRCA1	P38398-1.2	E1011Q	Neutral	0.219
BRCA1	P38398-1.2	E1011R	Pathogenic	0.552
BRCA1	P38398-1.2	E1011S	Pathogenic	0.535
BRCA1	P38398-1.2	E1011T	Pathogenic	0.513
BRCA1	P38398-1.2	E1011V	Pathogenic	0.533
BRCA1	P38398-1.2	E1011W	Pathogenic	0.83
BRCA1	P38398-1.2	E1011Y	Pathogenic	0.681
BRCA1	P38398-1.2	R1012A	Neutral	0.332
BRCA1	P38398-1.2	R1012C	Neutral	0.399
BRCA1	P38398-1.2	R1012D	Neutral	0.3
BRCA1	P38398-1.2	R1012E	Neutral	0.121
BRCA1	P38398-1.2	R1012F	Neutral	0.181
BRCA1	P38398-1.2	R1012G	Pathogenic	0.523
BRCA1	P38398-1.2	R1012H	Neutral	0.1
BRCA1	P38398-1.2	R1012I	Neutral	0.22
BRCA1	P38398-1.2	R1012K	Neutral	0.036
BRCA1	P38398-1.2	R1012L	Neutral	0.164
BRCA1	P38398-1.2	R1012M	Neutral	0.121
BRCA1	P38398-1.2	R1012N	Neutral	0.156
BRCA1	P38398-1.2	R1012P	Neutral	0.298
BRCA1	P38398-1.2	R1012Q	Neutral	0.079
BRCA1	P38398-1.2	R1012S	Neutral	0.304
BRCA1	P38398-1.2	R1012T	Neutral	0.218
BRCA1	P38398-1.2	R1012V	Neutral	0.303
BRCA1	P38398-1.2	R1012W	Neutral	0.186
BRCA1	P38398-1.2	R1012Y	Neutral	0.12
BRCA1	P38398-1.2	E1013A	Neutral	0.074
BRCA1	P38398-1.2	E1013C	Neutral	0.134
BRCA1	P38398-1.2	E1013D	Neutral	0.016
BRCA1	P38398-1.2	E1013F	Neutral	0.102
BRCA1	P38398-1.2	E1013G	Neutral	0.151
BRCA1	P38398-1.2	E1013H	Neutral	0.026
BRCA1	P38398-1.2	E1013I	Neutral	0.082
BRCA1	P38398-1.2	E1013K	Neutral	0.027
BRCA1	P38398-1.2	E1013L	Neutral	0.082
BRCA1	P38398-1.2	E1013M	Neutral	0.059
BRCA1	P38398-1.2	E1013N	Neutral	0.029
BRCA1	P38398-1.2	E1013P	Neutral	0.046
BRCA1	P38398-1.2	E1013Q	Neutral	0.012
BRCA1	P38398-1.2	E1013R	Neutral	0.05
BRCA1	P38398-1.2	E1013S	Neutral	0.047
BRCA1	P38398-1.2	E1013T	Neutral	0.043
BRCA1	P38398-1.2	E1013V	Neutral	0.047
BRCA1	P38398-1.2	E1013W	Neutral	0.173
BRCA1	P38398-1.2	E1013Y	Neutral	0.084
BRCA1	P38398-1.2	M1014A	Neutral	0.084
BRCA1	P38398-1.2	M1014C	Neutral	0.058
BRCA1	P38398-1.2	M1014D	Neutral	0.099
BRCA1	P38398-1.2	M1014E	Neutral	0.049
BRCA1	P38398-1.2	M1014F	Neutral	0.023
BRCA1	P38398-1.2	M1014G	Neutral	0.224
BRCA1	P38398-1.2	M1014H	Neutral	0.041
BRCA1	P38398-1.2	M1014I	Neutral	0.012
BRCA1	P38398-1.2	M1014K	Neutral	0.031
BRCA1	P38398-1.2	M1014L	Neutral	0.009
BRCA1	P38398-1.2	M1014N	Neutral	0.064
BRCA1	P38398-1.2	M1014P	Neutral	0.074
BRCA1	P38398-1.2	M1014Q	Neutral	0.022
BRCA1	P38398-1.2	M1014R	Neutral	0.041
BRCA1	P38398-1.2	M1014S	Neutral	0.074
BRCA1	P38398-1.2	M1014T	Neutral	0.049
BRCA1	P38398-1.2	M1014V	Neutral	0.019
BRCA1	P38398-1.2	M1014W	Neutral	0.058
BRCA1	P38398-1.2	M1014Y	Neutral	0.037
BRCA1	P38398-1.2	G1015A	Pathogenic	0.558
BRCA1	P38398-1.2	G1015C	Pathogenic	0.85
BRCA1	P38398-1.2	G1015D	Pathogenic	0.754
BRCA1	P38398-1.2	G1015E	Pathogenic	0.869
BRCA1	P38398-1.2	G1015F	Pathogenic	0.943
BRCA1	P38398-1.2	G1015H	Pathogenic	0.891
BRCA1	P38398-1.2	G1015I	Pathogenic	0.949
BRCA1	P38398-1.2	G1015K	Pathogenic	0.921
BRCA1	P38398-1.2	G1015L	Pathogenic	0.949
BRCA1	P38398-1.2	G1015M	Pathogenic	0.929
BRCA1	P38398-1.2	G1015N	Pathogenic	0.705
BRCA1	P38398-1.2	G1015P	Pathogenic	0.812
BRCA1	P38398-1.2	G1015Q	Pathogenic	0.882
BRCA1	P38398-1.2	G1015R	Pathogenic	0.94
BRCA1	P38398-1.2	G1015S	Pathogenic	0.592
BRCA1	P38398-1.2	G1015T	Pathogenic	0.824
BRCA1	P38398-1.2	G1015V	Pathogenic	0.896
BRCA1	P38398-1.2	G1015W	Pathogenic	0.955
BRCA1	P38398-1.2	G1015Y	Pathogenic	0.951
BRCA1	P38398-1.2	N1016A	Pathogenic	0.638
BRCA1	P38398-1.2	N1016C	Pathogenic	0.622
BRCA1	P38398-1.2	N1016D	Neutral	0.261
BRCA1	P38398-1.2	N1016E	Neutral	0.378
BRCA1	P38398-1.2	N1016F	Pathogenic	0.755
BRCA1	P38398-1.2	N1016G	Pathogenic	0.567
BRCA1	P38398-1.2	N1016H	Neutral	0.337
BRCA1	P38398-1.2	N1016I	Pathogenic	0.707
BRCA1	P38398-1.2	N1016K	Pathogenic	0.518
BRCA1	P38398-1.2	N1016L	Pathogenic	0.707
BRCA1	P38398-1.2	N1016M	Pathogenic	0.629
BRCA1	P38398-1.2	N1016P	Pathogenic	0.512
BRCA1	P38398-1.2	N1016Q	Neutral	0.403
BRCA1	P38398-1.2	N1016R	Pathogenic	0.589
BRCA1	P38398-1.2	N1016S	Neutral	0.343
BRCA1	P38398-1.2	N1016T	Neutral	0.324
BRCA1	P38398-1.2	N1016V	Pathogenic	0.615
BRCA1	P38398-1.2	N1016W	Pathogenic	0.891
BRCA1	P38398-1.2	N1016Y	Pathogenic	0.713
BRCA1	P38398-1.2	E1017A	Pathogenic	0.604
BRCA1	P38398-1.2	E1017C	Pathogenic	0.746
BRCA1	P38398-1.2	E1017D	Neutral	0.234
BRCA1	P38398-1.2	E1017F	Pathogenic	0.683
BRCA1	P38398-1.2	E1017G	Pathogenic	0.771
BRCA1	P38398-1.2	E1017H	Neutral	0.338
BRCA1	P38398-1.2	E1017I	Pathogenic	0.627
BRCA1	P38398-1.2	E1017K	Neutral	0.343
BRCA1	P38398-1.2	E1017L	Pathogenic	0.628
BRCA1	P38398-1.2	E1017M	Pathogenic	0.542
BRCA1	P38398-1.2	E1017N	Neutral	0.362
BRCA1	P38398-1.2	E1017P	Neutral	0.476
BRCA1	P38398-1.2	E1017Q	Neutral	0.185
BRCA1	P38398-1.2	E1017R	Pathogenic	0.501
BRCA1	P38398-1.2	E1017S	Neutral	0.483
BRCA1	P38398-1.2	E1017T	Neutral	0.461
BRCA1	P38398-1.2	E1017V	Neutral	0.481
BRCA1	P38398-1.2	E1017W	Pathogenic	0.799
BRCA1	P38398-1.2	E1017Y	Pathogenic	0.634
BRCA1	P38398-1.2	N1018A	Neutral	0.029
BRCA1	P38398-1.2	N1018C	Neutral	0.027
BRCA1	P38398-1.2	N1018D	Neutral	0.006
BRCA1	P38398-1.2	N1018E	Neutral	0.01
BRCA1	P38398-1.2	N1018F	Neutral	0.049
BRCA1	P38398-1.2	N1018G	Neutral	0.022
BRCA1	P38398-1.2	N1018H	Neutral	0.008
BRCA1	P38398-1.2	N1018I	Neutral	0.039
BRCA1	P38398-1.2	N1018K	Neutral	0.018
BRCA1	P38398-1.2	N1018L	Neutral	0.039
BRCA1	P38398-1.2	N1018M	Neutral	0.028
BRCA1	P38398-1.2	N1018P	Neutral	0.017
BRCA1	P38398-1.2	N1018Q	Neutral	0.011
BRCA1	P38398-1.2	N1018R	Neutral	0.024
BRCA1	P38398-1.2	N1018S	Neutral	0.009
BRCA1	P38398-1.2	N1018T	Neutral	0.008
BRCA1	P38398-1.2	N1018V	Neutral	0.026
BRCA1	P38398-1.2	N1018W	Neutral	0.121
BRCA1	P38398-1.2	N1018Y	Neutral	0.04
BRCA1	P38398-1.2	I1019A	Neutral	0.246
BRCA1	P38398-1.2	I1019C	Neutral	0.178
BRCA1	P38398-1.2	I1019D	Neutral	0.279
BRCA1	P38398-1.2	I1019E	Neutral	0.207
BRCA1	P38398-1.2	I1019F	Neutral	0.077
BRCA1	P38398-1.2	I1019G	Pathogenic	0.595
BRCA1	P38398-1.2	I1019H	Neutral	0.178
BRCA1	P38398-1.2	I1019K	Neutral	0.192
BRCA1	P38398-1.2	I1019L	Neutral	0.031
BRCA1	P38398-1.2	I1019M	Neutral	0.043
BRCA1	P38398-1.2	I1019N	Neutral	0.258
BRCA1	P38398-1.2	I1019P	Neutral	0.29
BRCA1	P38398-1.2	I1019Q	Neutral	0.19
BRCA1	P38398-1.2	I1019R	Neutral	0.24
BRCA1	P38398-1.2	I1019S	Neutral	0.29
BRCA1	P38398-1.2	I1019T	Neutral	0.154
BRCA1	P38398-1.2	I1019V	Neutral	0.032
BRCA1	P38398-1.2	I1019W	Neutral	0.316
BRCA1	P38398-1.2	I1019Y	Neutral	0.119
BRCA1	P38398-1.2	P1020A	Neutral	0.285
BRCA1	P38398-1.2	P1020C	Neutral	0.351
BRCA1	P38398-1.2	P1020D	Neutral	0.193
BRCA1	P38398-1.2	P1020E	Neutral	0.263
BRCA1	P38398-1.2	P1020F	Pathogenic	0.656
BRCA1	P38398-1.2	P1020G	Neutral	0.465
BRCA1	P38398-1.2	P1020H	Neutral	0.389
BRCA1	P38398-1.2	P1020I	Pathogenic	0.509
BRCA1	P38398-1.2	P1020K	Neutral	0.387
BRCA1	P38398-1.2	P1020L	Pathogenic	0.51
BRCA1	P38398-1.2	P1020M	Neutral	0.422
BRCA1	P38398-1.2	P1020N	Neutral	0.278
BRCA1	P38398-1.2	P1020Q	Neutral	0.287
BRCA1	P38398-1.2	P1020R	Pathogenic	0.548
BRCA1	P38398-1.2	P1020S	Neutral	0.257
BRCA1	P38398-1.2	P1020T	Neutral	0.203
BRCA1	P38398-1.2	P1020V	Neutral	0.324
BRCA1	P38398-1.2	P1020W	Pathogenic	0.779
BRCA1	P38398-1.2	P1020Y	Pathogenic	0.606
BRCA1	P38398-1.2	S1021A	Pathogenic	0.619
BRCA1	P38398-1.2	S1021C	Pathogenic	0.795
BRCA1	P38398-1.2	S1021D	Pathogenic	0.752
BRCA1	P38398-1.2	S1021E	Pathogenic	0.819
BRCA1	P38398-1.2	S1021F	Pathogenic	0.942
BRCA1	P38398-1.2	S1021G	Pathogenic	0.782
BRCA1	P38398-1.2	S1021H	Pathogenic	0.889
BRCA1	P38398-1.2	S1021I	Pathogenic	0.927
BRCA1	P38398-1.2	S1021K	Pathogenic	0.889
BRCA1	P38398-1.2	S1021L	Pathogenic	0.928
BRCA1	P38398-1.2	S1021M	Pathogenic	0.9
BRCA1	P38398-1.2	S1021N	Pathogenic	0.702
BRCA1	P38398-1.2	S1021P	Pathogenic	0.81
BRCA1	P38398-1.2	S1021Q	Pathogenic	0.836
BRCA1	P38398-1.2	S1021R	Pathogenic	0.939
BRCA1	P38398-1.2	S1021T	Pathogenic	0.689
BRCA1	P38398-1.2	S1021V	Pathogenic	0.894
BRCA1	P38398-1.2	S1021W	Pathogenic	0.977
BRCA1	P38398-1.2	S1021Y	Pathogenic	0.95
BRCA1	P38398-1.2	T1022A	Neutral	0.266
BRCA1	P38398-1.2	T1022C	Neutral	0.253
BRCA1	P38398-1.2	T1022D	Neutral	0.231
BRCA1	P38398-1.2	T1022E	Neutral	0.292
BRCA1	P38398-1.2	T1022F	Pathogenic	0.511
BRCA1	P38398-1.2	T1022G	Pathogenic	0.533
BRCA1	P38398-1.2	T1022H	Neutral	0.424
BRCA1	P38398-1.2	T1022I	Neutral	0.362
BRCA1	P38398-1.2	T1022K	Neutral	0.422
BRCA1	P38398-1.2	T1022L	Neutral	0.363
BRCA1	P38398-1.2	T1022M	Neutral	0.365
BRCA1	P38398-1.2	T1022N	Neutral	0.177
BRCA1	P38398-1.2	T1022P	Neutral	0.237
BRCA1	P38398-1.2	T1022Q	Neutral	0.317
BRCA1	P38398-1.2	T1022R	Neutral	0.493
BRCA1	P38398-1.2	T1022S	Neutral	0.18
BRCA1	P38398-1.2	T1022V	Neutral	0.207
BRCA1	P38398-1.2	T1022W	Pathogenic	0.658
BRCA1	P38398-1.2	T1022Y	Pathogenic	0.548
BRCA1	P38398-1.2	V1023A	Neutral	0.121
BRCA1	P38398-1.2	V1023C	Neutral	0.117
BRCA1	P38398-1.2	V1023D	Neutral	0.191
BRCA1	P38398-1.2	V1023E	Neutral	0.117
BRCA1	P38398-1.2	V1023F	Neutral	0.143
BRCA1	P38398-1.2	V1023G	Neutral	0.384
BRCA1	P38398-1.2	V1023H	Neutral	0.191
BRCA1	P38398-1.2	V1023I	Neutral	0.03
BRCA1	P38398-1.2	V1023K	Neutral	0.189
BRCA1	P38398-1.2	V1023L	Neutral	0.06
BRCA1	P38398-1.2	V1023M	Neutral	0.06
BRCA1	P38398-1.2	V1023N	Neutral	0.175
BRCA1	P38398-1.2	V1023P	Neutral	0.147
BRCA1	P38398-1.2	V1023Q	Neutral	0.129
BRCA1	P38398-1.2	V1023R	Neutral	0.31
BRCA1	P38398-1.2	V1023S	Neutral	0.199
BRCA1	P38398-1.2	V1023T	Neutral	0.072
BRCA1	P38398-1.2	V1023W	Neutral	0.39
BRCA1	P38398-1.2	V1023Y	Neutral	0.161
BRCA1	P38398-1.2	S1024A	Neutral	0.061
BRCA1	P38398-1.2	S1024C	Neutral	0.135
BRCA1	P38398-1.2	S1024D	Neutral	0.109
BRCA1	P38398-1.2	S1024E	Neutral	0.154
BRCA1	P38398-1.2	S1024F	Neutral	0.397
BRCA1	P38398-1.2	S1024G	Neutral	0.126
BRCA1	P38398-1.2	S1024H	Neutral	0.245
BRCA1	P38398-1.2	S1024I	Neutral	0.34
BRCA1	P38398-1.2	S1024K	Neutral	0.244
BRCA1	P38398-1.2	S1024L	Neutral	0.341
BRCA1	P38398-1.2	S1024M	Neutral	0.266
BRCA1	P38398-1.2	S1024N	Neutral	0.087
BRCA1	P38398-1.2	S1024P	Neutral	0.147
BRCA1	P38398-1.2	S1024Q	Neutral	0.171
BRCA1	P38398-1.2	S1024R	Neutral	0.383
BRCA1	P38398-1.2	S1024T	Neutral	0.082
BRCA1	P38398-1.2	S1024V	Neutral	0.255
BRCA1	P38398-1.2	S1024W	Pathogenic	0.636
BRCA1	P38398-1.2	S1024Y	Neutral	0.433
BRCA1	P38398-1.2	T1025A	Neutral	0.248
BRCA1	P38398-1.2	T1025C	Neutral	0.235
BRCA1	P38398-1.2	T1025D	Neutral	0.215
BRCA1	P38398-1.2	T1025E	Neutral	0.273
BRCA1	P38398-1.2	T1025F	Neutral	0.487
BRCA1	P38398-1.2	T1025G	Pathogenic	0.51
BRCA1	P38398-1.2	T1025H	Neutral	0.401
BRCA1	P38398-1.2	T1025I	Neutral	0.34
BRCA1	P38398-1.2	T1025K	Neutral	0.399
BRCA1	P38398-1.2	T1025L	Neutral	0.341
BRCA1	P38398-1.2	T1025M	Neutral	0.343
BRCA1	P38398-1.2	T1025N	Neutral	0.163
BRCA1	P38398-1.2	T1025P	Neutral	0.221
BRCA1	P38398-1.2	T1025Q	Neutral	0.297
BRCA1	P38398-1.2	T1025R	Neutral	0.469
BRCA1	P38398-1.2	T1025S	Neutral	0.167
BRCA1	P38398-1.2	T1025V	Neutral	0.192
BRCA1	P38398-1.2	T1025W	Pathogenic	0.637
BRCA1	P38398-1.2	T1025Y	Pathogenic	0.524
BRCA1	P38398-1.2	I1026A	Neutral	0.168
BRCA1	P38398-1.2	I1026C	Neutral	0.118
BRCA1	P38398-1.2	I1026D	Neutral	0.193
BRCA1	P38398-1.2	I1026E	Neutral	0.139
BRCA1	P38398-1.2	I1026F	Neutral	0.049
BRCA1	P38398-1.2	I1026G	Neutral	0.476
BRCA1	P38398-1.2	I1026H	Neutral	0.118
BRCA1	P38398-1.2	I1026K	Neutral	0.128
BRCA1	P38398-1.2	I1026L	Neutral	0.019
BRCA1	P38398-1.2	I1026M	Neutral	0.027
BRCA1	P38398-1.2	I1026N	Neutral	0.177
BRCA1	P38398-1.2	I1026P	Neutral	0.201
BRCA1	P38398-1.2	I1026Q	Neutral	0.127
BRCA1	P38398-1.2	I1026R	Neutral	0.163
BRCA1	P38398-1.2	I1026S	Neutral	0.201
BRCA1	P38398-1.2	I1026T	Neutral	0.101
BRCA1	P38398-1.2	I1026V	Neutral	0.02
BRCA1	P38398-1.2	I1026W	Neutral	0.222
BRCA1	P38398-1.2	I1026Y	Neutral	0.077
BRCA1	P38398-1.2	S1027A	Neutral	0.374
BRCA1	P38398-1.2	S1027C	Pathogenic	0.588
BRCA1	P38398-1.2	S1027D	Pathogenic	0.527
BRCA1	P38398-1.2	S1027E	Pathogenic	0.625
BRCA1	P38398-1.2	S1027F	Pathogenic	0.857
BRCA1	P38398-1.2	S1027G	Pathogenic	0.568
BRCA1	P38398-1.2	S1027H	Pathogenic	0.747
BRCA1	P38398-1.2	S1027I	Pathogenic	0.824
BRCA1	P38398-1.2	S1027K	Pathogenic	0.746
BRCA1	P38398-1.2	S1027L	Pathogenic	0.825
BRCA1	P38398-1.2	S1027M	Pathogenic	0.767
BRCA1	P38398-1.2	S1027N	Neutral	0.464
BRCA1	P38398-1.2	S1027P	Pathogenic	0.61
BRCA1	P38398-1.2	S1027Q	Pathogenic	0.652
BRCA1	P38398-1.2	S1027R	Pathogenic	0.85
BRCA1	P38398-1.2	S1027T	Neutral	0.449
BRCA1	P38398-1.2	S1027V	Pathogenic	0.757
BRCA1	P38398-1.2	S1027W	Pathogenic	0.941
BRCA1	P38398-1.2	S1027Y	Pathogenic	0.874
BRCA1	P38398-1.2	R1028A	Neutral	0.027
BRCA1	P38398-1.2	R1028C	Neutral	0.036
BRCA1	P38398-1.2	R1028D	Neutral	0.024
BRCA1	P38398-1.2	R1028E	Neutral	0.008
BRCA1	P38398-1.2	R1028F	Neutral	0.012
BRCA1	P38398-1.2	R1028G	Neutral	0.058
BRCA1	P38398-1.2	R1028H	Neutral	0.006
BRCA1	P38398-1.2	R1028I	Neutral	0.016
BRCA1	P38398-1.2	R1028K	Neutral	0.002
BRCA1	P38398-1.2	R1028L	Neutral	0.011
BRCA1	P38398-1.2	R1028M	Neutral	0.008
BRCA1	P38398-1.2	R1028N	Neutral	0.01
BRCA1	P38398-1.2	R1028P	Neutral	0.023
BRCA1	P38398-1.2	R1028Q	Neutral	0.005
BRCA1	P38398-1.2	R1028S	Neutral	0.024
BRCA1	P38398-1.2	R1028T	Neutral	0.015
BRCA1	P38398-1.2	R1028V	Neutral	0.024
BRCA1	P38398-1.2	R1028W	Neutral	0.013
BRCA1	P38398-1.2	R1028Y	Neutral	0.008
BRCA1	P38398-1.2	N1029A	Neutral	0.126
BRCA1	P38398-1.2	N1029C	Neutral	0.119
BRCA1	P38398-1.2	N1029D	Neutral	0.028
BRCA1	P38398-1.2	N1029E	Neutral	0.047
BRCA1	P38398-1.2	N1029F	Neutral	0.202
BRCA1	P38398-1.2	N1029G	Neutral	0.097
BRCA1	P38398-1.2	N1029H	Neutral	0.04
BRCA1	P38398-1.2	N1029I	Neutral	0.165
BRCA1	P38398-1.2	N1029K	Neutral	0.081
BRCA1	P38398-1.2	N1029L	Neutral	0.165
BRCA1	P38398-1.2	N1029M	Neutral	0.122
BRCA1	P38398-1.2	N1029P	Neutral	0.079
BRCA1	P38398-1.2	N1029Q	Neutral	0.052
BRCA1	P38398-1.2	N1029R	Neutral	0.105
BRCA1	P38398-1.2	N1029S	Neutral	0.041
BRCA1	P38398-1.2	N1029T	Neutral	0.038
BRCA1	P38398-1.2	N1029V	Neutral	0.116
BRCA1	P38398-1.2	N1029W	Neutral	0.402
BRCA1	P38398-1.2	N1029Y	Neutral	0.169
BRCA1	P38398-1.2	N1030A	Pathogenic	0.586
BRCA1	P38398-1.2	N1030C	Pathogenic	0.569
BRCA1	P38398-1.2	N1030D	Neutral	0.221
BRCA1	P38398-1.2	N1030E	Neutral	0.328
BRCA1	P38398-1.2	N1030F	Pathogenic	0.712
BRCA1	P38398-1.2	N1030G	Pathogenic	0.512
BRCA1	P38398-1.2	N1030H	Neutral	0.29
BRCA1	P38398-1.2	N1030I	Pathogenic	0.66
BRCA1	P38398-1.2	N1030K	Neutral	0.463
BRCA1	P38398-1.2	N1030L	Pathogenic	0.66
BRCA1	P38398-1.2	N1030M	Pathogenic	0.577
BRCA1	P38398-1.2	N1030P	Neutral	0.458
BRCA1	P38398-1.2	N1030Q	Neutral	0.351
BRCA1	P38398-1.2	N1030R	Pathogenic	0.535
BRCA1	P38398-1.2	N1030S	Neutral	0.295
BRCA1	P38398-1.2	N1030T	Neutral	0.278
BRCA1	P38398-1.2	N1030V	Pathogenic	0.563
BRCA1	P38398-1.2	N1030W	Pathogenic	0.868
BRCA1	P38398-1.2	N1030Y	Pathogenic	0.666
BRCA1	P38398-1.2	I1031A	Neutral	0.158
BRCA1	P38398-1.2	I1031C	Neutral	0.111
BRCA1	P38398-1.2	I1031D	Neutral	0.183
BRCA1	P38398-1.2	I1031E	Neutral	0.131
BRCA1	P38398-1.2	I1031F	Neutral	0.046
BRCA1	P38398-1.2	I1031G	Neutral	0.46
BRCA1	P38398-1.2	I1031H	Neutral	0.111
BRCA1	P38398-1.2	I1031K	Neutral	0.12
BRCA1	P38398-1.2	I1031L	Neutral	0.018
BRCA1	P38398-1.2	I1031M	Neutral	0.025
BRCA1	P38398-1.2	I1031N	Neutral	0.167
BRCA1	P38398-1.2	I1031P	Neutral	0.191
BRCA1	P38398-1.2	I1031Q	Neutral	0.12
BRCA1	P38398-1.2	I1031R	Neutral	0.154
BRCA1	P38398-1.2	I1031S	Neutral	0.191
BRCA1	P38398-1.2	I1031T	Neutral	0.095
BRCA1	P38398-1.2	I1031V	Neutral	0.019
BRCA1	P38398-1.2	I1031W	Neutral	0.211
BRCA1	P38398-1.2	I1031Y	Neutral	0.073
BRCA1	P38398-1.2	R1032A	Pathogenic	0.883
BRCA1	P38398-1.2	R1032C	Pathogenic	0.91
BRCA1	P38398-1.2	R1032D	Pathogenic	0.867
BRCA1	P38398-1.2	R1032E	Pathogenic	0.677
BRCA1	P38398-1.2	R1032F	Pathogenic	0.77
BRCA1	P38398-1.2	R1032G	Pathogenic	0.943
BRCA1	P38398-1.2	R1032H	Pathogenic	0.629
BRCA1	P38398-1.2	R1032I	Pathogenic	0.811
BRCA1	P38398-1.2	R1032K	Neutral	0.364
BRCA1	P38398-1.2	R1032L	Pathogenic	0.749
BRCA1	P38398-1.2	R1032M	Pathogenic	0.676
BRCA1	P38398-1.2	R1032N	Pathogenic	0.737
BRCA1	P38398-1.2	R1032P	Pathogenic	0.866
BRCA1	P38398-1.2	R1032Q	Pathogenic	0.564
BRCA1	P38398-1.2	R1032S	Pathogenic	0.869
BRCA1	P38398-1.2	R1032T	Pathogenic	0.809
BRCA1	P38398-1.2	R1032V	Pathogenic	0.868
BRCA1	P38398-1.2	R1032W	Pathogenic	0.777
BRCA1	P38398-1.2	R1032Y	Pathogenic	0.675
BRCA1	P38398-1.2	E1033A	Neutral	0.234
BRCA1	P38398-1.2	E1033C	Neutral	0.371
BRCA1	P38398-1.2	E1033D	Neutral	0.058
BRCA1	P38398-1.2	E1033F	Neutral	0.301
BRCA1	P38398-1.2	E1033G	Neutral	0.403
BRCA1	P38398-1.2	E1033H	Neutral	0.093
BRCA1	P38398-1.2	E1033I	Neutral	0.253
BRCA1	P38398-1.2	E1033K	Neutral	0.095
BRCA1	P38398-1.2	E1033L	Neutral	0.253
BRCA1	P38398-1.2	E1033M	Neutral	0.192
BRCA1	P38398-1.2	E1033N	Neutral	0.102
BRCA1	P38398-1.2	E1033P	Neutral	0.154
BRCA1	P38398-1.2	E1033Q	Neutral	0.044
BRCA1	P38398-1.2	E1033R	Neutral	0.167
BRCA1	P38398-1.2	E1033S	Neutral	0.158
BRCA1	P38398-1.2	E1033T	Neutral	0.147
BRCA1	P38398-1.2	E1033V	Neutral	0.157
BRCA1	P38398-1.2	E1033W	Neutral	0.443
BRCA1	P38398-1.2	E1033Y	Neutral	0.258
BRCA1	P38398-1.2	N1034A	Neutral	0.005
BRCA1	P38398-1.2	N1034C	Neutral	0.005
BRCA1	P38398-1.2	N1034D	Neutral	0.001
BRCA1	P38398-1.2	N1034E	Neutral	0.002
BRCA1	P38398-1.2	N1034F	Neutral	0.01
BRCA1	P38398-1.2	N1034G	Neutral	0.004
BRCA1	P38398-1.2	N1034H	Neutral	0.002
BRCA1	P38398-1.2	N1034I	Neutral	0.008
BRCA1	P38398-1.2	N1034K	Neutral	0.003
BRCA1	P38398-1.2	N1034L	Neutral	0.008
BRCA1	P38398-1.2	N1034M	Neutral	0.005
BRCA1	P38398-1.2	N1034P	Neutral	0.003
BRCA1	P38398-1.2	N1034Q	Neutral	0.002
BRCA1	P38398-1.2	N1034R	Neutral	0.004
BRCA1	P38398-1.2	N1034S	Neutral	0.002
BRCA1	P38398-1.2	N1034T	Neutral	0.001
BRCA1	P38398-1.2	N1034V	Neutral	0.005
BRCA1	P38398-1.2	N1034W	Neutral	0.025
BRCA1	P38398-1.2	N1034Y	Neutral	0.008
BRCA1	P38398-1.2	V1035A	Neutral	0.019
BRCA1	P38398-1.2	V1035C	Neutral	0.018
BRCA1	P38398-1.2	V1035D	Neutral	0.031
BRCA1	P38398-1.2	V1035E	Neutral	0.018
BRCA1	P38398-1.2	V1035F	Neutral	0.022
BRCA1	P38398-1.2	V1035G	Neutral	0.079
BRCA1	P38398-1.2	V1035H	Neutral	0.031
BRCA1	P38398-1.2	V1035I	Neutral	0.004
BRCA1	P38398-1.2	V1035K	Neutral	0.031
BRCA1	P38398-1.2	V1035L	Neutral	0.009
BRCA1	P38398-1.2	V1035M	Neutral	0.009
BRCA1	P38398-1.2	V1035N	Neutral	0.028
BRCA1	P38398-1.2	V1035P	Neutral	0.023
BRCA1	P38398-1.2	V1035Q	Neutral	0.02
BRCA1	P38398-1.2	V1035R	Neutral	0.058
BRCA1	P38398-1.2	V1035S	Neutral	0.033
BRCA1	P38398-1.2	V1035T	Neutral	0.011
BRCA1	P38398-1.2	V1035W	Neutral	0.081
BRCA1	P38398-1.2	V1035Y	Neutral	0.026
BRCA1	P38398-1.2	F1036A	Neutral	0.046
BRCA1	P38398-1.2	F1036C	Neutral	0.031
BRCA1	P38398-1.2	F1036D	Neutral	0.039
BRCA1	P38398-1.2	F1036E	Neutral	0.026
BRCA1	P38398-1.2	F1036G	Neutral	0.096
BRCA1	P38398-1.2	F1036H	Neutral	0.011
BRCA1	P38398-1.2	F1036I	Neutral	0.007
BRCA1	P38398-1.2	F1036K	Neutral	0.015
BRCA1	P38398-1.2	F1036L	Neutral	0.007
BRCA1	P38398-1.2	F1036M	Neutral	0.007
BRCA1	P38398-1.2	F1036N	Neutral	0.035
BRCA1	P38398-1.2	F1036P	Neutral	0.057
BRCA1	P38398-1.2	F1036Q	Neutral	0.024
BRCA1	P38398-1.2	F1036R	Neutral	0.02
BRCA1	P38398-1.2	F1036S	Neutral	0.041
BRCA1	P38398-1.2	F1036T	Neutral	0.027
BRCA1	P38398-1.2	F1036V	Neutral	0.015
BRCA1	P38398-1.2	F1036W	Neutral	0.007
BRCA1	P38398-1.2	F1036Y	Neutral	0.002
BRCA1	P38398-1.2	K1037A	Pathogenic	0.89
BRCA1	P38398-1.2	K1037C	Pathogenic	0.915
BRCA1	P38398-1.2	K1037D	Pathogenic	0.829
BRCA1	P38398-1.2	K1037E	Pathogenic	0.609
BRCA1	P38398-1.2	K1037F	Pathogenic	0.782
BRCA1	P38398-1.2	K1037G	Pathogenic	0.947
BRCA1	P38398-1.2	K1037H	Pathogenic	0.723
BRCA1	P38398-1.2	K1037I	Pathogenic	0.821
BRCA1	P38398-1.2	K1037L	Pathogenic	0.761
BRCA1	P38398-1.2	K1037M	Pathogenic	0.691
BRCA1	P38398-1.2	K1037N	Pathogenic	0.75
BRCA1	P38398-1.2	K1037P	Pathogenic	0.828
BRCA1	P38398-1.2	K1037Q	Pathogenic	0.581
BRCA1	P38398-1.2	K1037R	Neutral	0.45
BRCA1	P38398-1.2	K1037S	Pathogenic	0.832
BRCA1	P38398-1.2	K1037T	Pathogenic	0.819
BRCA1	P38398-1.2	K1037V	Pathogenic	0.831
BRCA1	P38398-1.2	K1037W	Pathogenic	0.869
BRCA1	P38398-1.2	K1037Y	Pathogenic	0.743
BRCA1	P38398-1.2	E1038A	Pathogenic	0.684
BRCA1	P38398-1.2	E1038C	Pathogenic	0.807
BRCA1	P38398-1.2	E1038D	Neutral	0.302
BRCA1	P38398-1.2	E1038F	Pathogenic	0.753
BRCA1	P38398-1.2	E1038G	Pathogenic	0.827
BRCA1	P38398-1.2	E1038H	Neutral	0.42
BRCA1	P38398-1.2	E1038I	Pathogenic	0.705
BRCA1	P38398-1.2	E1038K	Neutral	0.426
BRCA1	P38398-1.2	E1038L	Pathogenic	0.706
BRCA1	P38398-1.2	E1038M	Pathogenic	0.627
BRCA1	P38398-1.2	E1038N	Neutral	0.446
BRCA1	P38398-1.2	E1038P	Pathogenic	0.563
BRCA1	P38398-1.2	E1038Q	Neutral	0.244
BRCA1	P38398-1.2	E1038R	Pathogenic	0.587
BRCA1	P38398-1.2	E1038S	Pathogenic	0.57
BRCA1	P38398-1.2	E1038T	Pathogenic	0.549
BRCA1	P38398-1.2	E1038V	Pathogenic	0.568
BRCA1	P38398-1.2	E1038W	Pathogenic	0.849
BRCA1	P38398-1.2	E1038Y	Pathogenic	0.711
BRCA1	P38398-1.2	A1039C	Neutral	0.017
BRCA1	P38398-1.2	A1039D	Neutral	0.038
BRCA1	P38398-1.2	A1039E	Neutral	0.04
BRCA1	P38398-1.2	A1039F	Neutral	0.095
BRCA1	P38398-1.2	A1039G	Neutral	0.017
BRCA1	P38398-1.2	A1039H	Neutral	0.069
BRCA1	P38398-1.2	A1039I	Neutral	0.054
BRCA1	P38398-1.2	A1039K	Neutral	0.068
BRCA1	P38398-1.2	A1039L	Neutral	0.054
BRCA1	P38398-1.2	A1039M	Neutral	0.054
BRCA1	P38398-1.2	A1039N	Neutral	0.043
BRCA1	P38398-1.2	A1039P	Neutral	0.027
BRCA1	P38398-1.2	A1039Q	Neutral	0.044
BRCA1	P38398-1.2	A1039R	Neutral	0.089
BRCA1	P38398-1.2	A1039S	Neutral	0.009
BRCA1	P38398-1.2	A1039T	Neutral	0.02
BRCA1	P38398-1.2	A1039V	Neutral	0.026
BRCA1	P38398-1.2	A1039W	Neutral	0.218
BRCA1	P38398-1.2	A1039Y	Neutral	0.108
BRCA1	P38398-1.2	S1040A	Neutral	0.133
BRCA1	P38398-1.2	S1040C	Neutral	0.268
BRCA1	P38398-1.2	S1040D	Neutral	0.223
BRCA1	P38398-1.2	S1040E	Neutral	0.3
BRCA1	P38398-1.2	S1040F	Pathogenic	0.607
BRCA1	P38398-1.2	S1040G	Neutral	0.253
BRCA1	P38398-1.2	S1040H	Neutral	0.432
BRCA1	P38398-1.2	S1040I	Pathogenic	0.547
BRCA1	P38398-1.2	S1040K	Neutral	0.431
BRCA1	P38398-1.2	S1040L	Pathogenic	0.548
BRCA1	P38398-1.2	S1040M	Neutral	0.459
BRCA1	P38398-1.2	S1040N	Neutral	0.182
BRCA1	P38398-1.2	S1040P	Neutral	0.287
BRCA1	P38398-1.2	S1040Q	Neutral	0.326
BRCA1	P38398-1.2	S1040R	Pathogenic	0.593
BRCA1	P38398-1.2	S1040T	Neutral	0.174
BRCA1	P38398-1.2	S1040V	Neutral	0.445
BRCA1	P38398-1.2	S1040W	Pathogenic	0.804
BRCA1	P38398-1.2	S1040Y	Pathogenic	0.642
BRCA1	P38398-1.2	S1041A	Pathogenic	0.567
BRCA1	P38398-1.2	S1041C	Pathogenic	0.758
BRCA1	P38398-1.2	S1041D	Pathogenic	0.71
BRCA1	P38398-1.2	S1041E	Pathogenic	0.785
BRCA1	P38398-1.2	S1041F	Pathogenic	0.929
BRCA1	P38398-1.2	S1041G	Pathogenic	0.743
BRCA1	P38398-1.2	S1041H	Pathogenic	0.866
BRCA1	P38398-1.2	S1041I	Pathogenic	0.912
BRCA1	P38398-1.2	S1041K	Pathogenic	0.866
BRCA1	P38398-1.2	S1041L	Pathogenic	0.912
BRCA1	P38398-1.2	S1041M	Pathogenic	0.879
BRCA1	P38398-1.2	S1041N	Pathogenic	0.656
BRCA1	P38398-1.2	S1041P	Pathogenic	0.775
BRCA1	P38398-1.2	S1041Q	Pathogenic	0.805
BRCA1	P38398-1.2	S1041R	Pathogenic	0.925
BRCA1	P38398-1.2	S1041T	Pathogenic	0.642
BRCA1	P38398-1.2	S1041V	Pathogenic	0.872
BRCA1	P38398-1.2	S1041W	Pathogenic	0.972
BRCA1	P38398-1.2	S1041Y	Pathogenic	0.939
BRCA1	P38398-1.2	S1042A	Neutral	0.093
BRCA1	P38398-1.2	S1042C	Neutral	0.197
BRCA1	P38398-1.2	S1042D	Neutral	0.161
BRCA1	P38398-1.2	S1042E	Neutral	0.223
BRCA1	P38398-1.2	S1042F	Pathogenic	0.508
BRCA1	P38398-1.2	S1042G	Neutral	0.185
BRCA1	P38398-1.2	S1042H	Neutral	0.337
BRCA1	P38398-1.2	S1042I	Neutral	0.447
BRCA1	P38398-1.2	S1042K	Neutral	0.337
BRCA1	P38398-1.2	S1042L	Neutral	0.448
BRCA1	P38398-1.2	S1042M	Neutral	0.363
BRCA1	P38398-1.2	S1042N	Neutral	0.13
BRCA1	P38398-1.2	S1042P	Neutral	0.213
BRCA1	P38398-1.2	S1042Q	Neutral	0.244
BRCA1	P38398-1.2	S1042R	Neutral	0.494
BRCA1	P38398-1.2	S1042T	Neutral	0.123
BRCA1	P38398-1.2	S1042V	Neutral	0.349
BRCA1	P38398-1.2	S1042W	Pathogenic	0.733
BRCA1	P38398-1.2	S1042Y	Pathogenic	0.546
BRCA1	P38398-1.2	N1043A	Neutral	0.193
BRCA1	P38398-1.2	N1043C	Neutral	0.182
BRCA1	P38398-1.2	N1043D	Neutral	0.046
BRCA1	P38398-1.2	N1043E	Neutral	0.076
BRCA1	P38398-1.2	N1043F	Neutral	0.294
BRCA1	P38398-1.2	N1043G	Neutral	0.15
BRCA1	P38398-1.2	N1043H	Neutral	0.064
BRCA1	P38398-1.2	N1043I	Neutral	0.246
BRCA1	P38398-1.2	N1043K	Neutral	0.127
BRCA1	P38398-1.2	N1043L	Neutral	0.247
BRCA1	P38398-1.2	N1043M	Neutral	0.187
BRCA1	P38398-1.2	N1043P	Neutral	0.124
BRCA1	P38398-1.2	N1043Q	Neutral	0.084
BRCA1	P38398-1.2	N1043R	Neutral	0.163
BRCA1	P38398-1.2	N1043S	Neutral	0.066
BRCA1	P38398-1.2	N1043T	Neutral	0.061
BRCA1	P38398-1.2	N1043V	Neutral	0.178
BRCA1	P38398-1.2	N1043W	Pathogenic	0.526
BRCA1	P38398-1.2	N1043Y	Neutral	0.252
BRCA1	P38398-1.2	I1044A	Neutral	0.019
BRCA1	P38398-1.2	I1044C	Neutral	0.013
BRCA1	P38398-1.2	I1044D	Neutral	0.023
BRCA1	P38398-1.2	I1044E	Neutral	0.016
BRCA1	P38398-1.2	I1044F	Neutral	0.005
BRCA1	P38398-1.2	I1044G	Neutral	0.082
BRCA1	P38398-1.2	I1044H	Neutral	0.013
BRCA1	P38398-1.2	I1044K	Neutral	0.014
BRCA1	P38398-1.2	I1044L	Neutral	0.002
BRCA1	P38398-1.2	I1044M	Neutral	0.003
BRCA1	P38398-1.2	I1044N	Neutral	0.021
BRCA1	P38398-1.2	I1044P	Neutral	0.024
BRCA1	P38398-1.2	I1044Q	Neutral	0.014
BRCA1	P38398-1.2	I1044R	Neutral	0.019
BRCA1	P38398-1.2	I1044S	Neutral	0.024
BRCA1	P38398-1.2	I1044T	Neutral	0.011
BRCA1	P38398-1.2	I1044V	Neutral	0.002
BRCA1	P38398-1.2	I1044W	Neutral	0.027
BRCA1	P38398-1.2	I1044Y	Neutral	0.008
BRCA1	P38398-1.2	N1045A	Pathogenic	0.547
BRCA1	P38398-1.2	N1045C	Pathogenic	0.529
BRCA1	P38398-1.2	N1045D	Neutral	0.194
BRCA1	P38398-1.2	N1045E	Neutral	0.294
BRCA1	P38398-1.2	N1045F	Pathogenic	0.678
BRCA1	P38398-1.2	N1045G	Neutral	0.472
BRCA1	P38398-1.2	N1045H	Neutral	0.258
BRCA1	P38398-1.2	N1045I	Pathogenic	0.623
BRCA1	P38398-1.2	N1045K	Neutral	0.424
BRCA1	P38398-1.2	N1045L	Pathogenic	0.623
BRCA1	P38398-1.2	N1045M	Pathogenic	0.537
BRCA1	P38398-1.2	N1045P	Neutral	0.418
BRCA1	P38398-1.2	N1045Q	Neutral	0.316
BRCA1	P38398-1.2	N1045R	Neutral	0.495
BRCA1	P38398-1.2	N1045S	Neutral	0.263
BRCA1	P38398-1.2	N1045T	Neutral	0.247
BRCA1	P38398-1.2	N1045V	Pathogenic	0.523
BRCA1	P38398-1.2	N1045W	Pathogenic	0.849
BRCA1	P38398-1.2	N1045Y	Pathogenic	0.63
BRCA1	P38398-1.2	E1046A	Pathogenic	0.749
BRCA1	P38398-1.2	E1046C	Pathogenic	0.852
BRCA1	P38398-1.2	E1046D	Neutral	0.374
BRCA1	P38398-1.2	E1046F	Pathogenic	0.808
BRCA1	P38398-1.2	E1046G	Pathogenic	0.868
BRCA1	P38398-1.2	E1046H	Pathogenic	0.5
BRCA1	P38398-1.2	E1046I	Pathogenic	0.768
BRCA1	P38398-1.2	E1046K	Pathogenic	0.506
BRCA1	P38398-1.2	E1046L	Pathogenic	0.768
BRCA1	P38398-1.2	E1046M	Pathogenic	0.699
BRCA1	P38398-1.2	E1046N	Pathogenic	0.526
BRCA1	P38398-1.2	E1046P	Pathogenic	0.64
BRCA1	P38398-1.2	E1046Q	Neutral	0.308
BRCA1	P38398-1.2	E1046R	Pathogenic	0.663
BRCA1	P38398-1.2	E1046S	Pathogenic	0.647
BRCA1	P38398-1.2	E1046T	Pathogenic	0.627
BRCA1	P38398-1.2	E1046V	Pathogenic	0.645
BRCA1	P38398-1.2	E1046W	Pathogenic	0.886
BRCA1	P38398-1.2	E1046Y	Pathogenic	0.773
BRCA1	P38398-1.2	V1047A	Neutral	0.221
BRCA1	P38398-1.2	V1047C	Neutral	0.213
BRCA1	P38398-1.2	V1047D	Neutral	0.327
BRCA1	P38398-1.2	V1047E	Neutral	0.213
BRCA1	P38398-1.2	V1047F	Neutral	0.256
BRCA1	P38398-1.2	V1047G	Pathogenic	0.561
BRCA1	P38398-1.2	V1047H	Neutral	0.325
BRCA1	P38398-1.2	V1047I	Neutral	0.059
BRCA1	P38398-1.2	V1047K	Neutral	0.324
BRCA1	P38398-1.2	V1047L	Neutral	0.115
BRCA1	P38398-1.2	V1047M	Neutral	0.116
BRCA1	P38398-1.2	V1047N	Neutral	0.303
BRCA1	P38398-1.2	V1047P	Neutral	0.262
BRCA1	P38398-1.2	V1047Q	Neutral	0.234
BRCA1	P38398-1.2	V1047R	Neutral	0.479
BRCA1	P38398-1.2	V1047S	Neutral	0.338
BRCA1	P38398-1.2	V1047T	Neutral	0.137
BRCA1	P38398-1.2	V1047W	Pathogenic	0.567
BRCA1	P38398-1.2	V1047Y	Neutral	0.283
BRCA1	P38398-1.2	G1048A	Neutral	0.315
BRCA1	P38398-1.2	G1048C	Pathogenic	0.674
BRCA1	P38398-1.2	G1048D	Pathogenic	0.528
BRCA1	P38398-1.2	G1048E	Pathogenic	0.707
BRCA1	P38398-1.2	G1048F	Pathogenic	0.858
BRCA1	P38398-1.2	G1048H	Pathogenic	0.748
BRCA1	P38398-1.2	G1048I	Pathogenic	0.872
BRCA1	P38398-1.2	G1048K	Pathogenic	0.81
BRCA1	P38398-1.2	G1048L	Pathogenic	0.872
BRCA1	P38398-1.2	G1048M	Pathogenic	0.827
BRCA1	P38398-1.2	G1048N	Neutral	0.466
BRCA1	P38398-1.2	G1048P	Pathogenic	0.612
BRCA1	P38398-1.2	G1048Q	Pathogenic	0.731
BRCA1	P38398-1.2	G1048R	Pathogenic	0.85
BRCA1	P38398-1.2	G1048S	Neutral	0.346
BRCA1	P38398-1.2	G1048T	Pathogenic	0.63
BRCA1	P38398-1.2	G1048V	Pathogenic	0.758
BRCA1	P38398-1.2	G1048W	Pathogenic	0.886
BRCA1	P38398-1.2	G1048Y	Pathogenic	0.875
BRCA1	P38398-1.2	S1049A	Neutral	0.103
BRCA1	P38398-1.2	S1049C	Neutral	0.215
BRCA1	P38398-1.2	S1049D	Neutral	0.177
BRCA1	P38398-1.2	S1049E	Neutral	0.243
BRCA1	P38398-1.2	S1049F	Pathogenic	0.536
BRCA1	P38398-1.2	S1049G	Neutral	0.202
BRCA1	P38398-1.2	S1049H	Neutral	0.362
BRCA1	P38398-1.2	S1049I	Neutral	0.475
BRCA1	P38398-1.2	S1049K	Neutral	0.362
BRCA1	P38398-1.2	S1049L	Neutral	0.476
BRCA1	P38398-1.2	S1049M	Neutral	0.389
BRCA1	P38398-1.2	S1049N	Neutral	0.143
BRCA1	P38398-1.2	S1049P	Neutral	0.232
BRCA1	P38398-1.2	S1049Q	Neutral	0.265
BRCA1	P38398-1.2	S1049R	Pathogenic	0.521
BRCA1	P38398-1.2	S1049T	Neutral	0.136
BRCA1	P38398-1.2	S1049V	Neutral	0.375
BRCA1	P38398-1.2	S1049W	Pathogenic	0.754
BRCA1	P38398-1.2	S1049Y	Pathogenic	0.573
BRCA1	P38398-1.2	S1050A	Neutral	0.246
BRCA1	P38398-1.2	S1050C	Neutral	0.438
BRCA1	P38398-1.2	S1050D	Neutral	0.379
BRCA1	P38398-1.2	S1050E	Neutral	0.477
BRCA1	P38398-1.2	S1050F	Pathogenic	0.767
BRCA1	P38398-1.2	S1050G	Neutral	0.419
BRCA1	P38398-1.2	S1050H	Pathogenic	0.618
BRCA1	P38398-1.2	S1050I	Pathogenic	0.72
BRCA1	P38398-1.2	S1050K	Pathogenic	0.617
BRCA1	P38398-1.2	S1050L	Pathogenic	0.72
BRCA1	P38398-1.2	S1050M	Pathogenic	0.644
BRCA1	P38398-1.2	S1050N	Neutral	0.322
BRCA1	P38398-1.2	S1050P	Neutral	0.462
BRCA1	P38398-1.2	S1050Q	Pathogenic	0.507
BRCA1	P38398-1.2	S1050R	Pathogenic	0.756
BRCA1	P38398-1.2	S1050T	Neutral	0.309
BRCA1	P38398-1.2	S1050V	Pathogenic	0.63
BRCA1	P38398-1.2	S1050W	Pathogenic	0.897
BRCA1	P38398-1.2	S1050Y	Pathogenic	0.792
BRCA1	P38398-1.2	T1051A	Neutral	0.273
BRCA1	P38398-1.2	T1051C	Neutral	0.26
BRCA1	P38398-1.2	T1051D	Neutral	0.238
BRCA1	P38398-1.2	T1051E	Neutral	0.299
BRCA1	P38398-1.2	T1051F	Pathogenic	0.519
BRCA1	P38398-1.2	T1051G	Pathogenic	0.542
BRCA1	P38398-1.2	T1051H	Neutral	0.432
BRCA1	P38398-1.2	T1051I	Neutral	0.37
BRCA1	P38398-1.2	T1051K	Neutral	0.43
BRCA1	P38398-1.2	T1051L	Neutral	0.371
BRCA1	P38398-1.2	T1051M	Neutral	0.373
BRCA1	P38398-1.2	T1051N	Neutral	0.182
BRCA1	P38398-1.2	T1051P	Neutral	0.244
BRCA1	P38398-1.2	T1051Q	Neutral	0.325
BRCA1	P38398-1.2	T1051R	Pathogenic	0.502
BRCA1	P38398-1.2	T1051S	Neutral	0.185
BRCA1	P38398-1.2	T1051V	Neutral	0.213
BRCA1	P38398-1.2	T1051W	Pathogenic	0.666
BRCA1	P38398-1.2	T1051Y	Pathogenic	0.556
BRCA1	P38398-1.2	N1052A	Pathogenic	0.542
BRCA1	P38398-1.2	N1052C	Pathogenic	0.524
BRCA1	P38398-1.2	N1052D	Neutral	0.191
BRCA1	P38398-1.2	N1052E	Neutral	0.289
BRCA1	P38398-1.2	N1052F	Pathogenic	0.674
BRCA1	P38398-1.2	N1052G	Neutral	0.467
BRCA1	P38398-1.2	N1052H	Neutral	0.254
BRCA1	P38398-1.2	N1052I	Pathogenic	0.618
BRCA1	P38398-1.2	N1052K	Neutral	0.419
BRCA1	P38398-1.2	N1052L	Pathogenic	0.619
BRCA1	P38398-1.2	N1052M	Pathogenic	0.532
BRCA1	P38398-1.2	N1052P	Neutral	0.413
BRCA1	P38398-1.2	N1052Q	Neutral	0.311
BRCA1	P38398-1.2	N1052R	Neutral	0.49
BRCA1	P38398-1.2	N1052S	Neutral	0.259
BRCA1	P38398-1.2	N1052T	Neutral	0.243
BRCA1	P38398-1.2	N1052V	Pathogenic	0.518
BRCA1	P38398-1.2	N1052W	Pathogenic	0.846
BRCA1	P38398-1.2	N1052Y	Pathogenic	0.625
BRCA1	P38398-1.2	E1053A	Neutral	0.409
BRCA1	P38398-1.2	E1053C	Pathogenic	0.572
BRCA1	P38398-1.2	E1053D	Neutral	0.122
BRCA1	P38398-1.2	E1053F	Neutral	0.494
BRCA1	P38398-1.2	E1053G	Pathogenic	0.605
BRCA1	P38398-1.2	E1053H	Neutral	0.188
BRCA1	P38398-1.2	E1053I	Neutral	0.434
BRCA1	P38398-1.2	E1053K	Neutral	0.192
BRCA1	P38398-1.2	E1053L	Neutral	0.434
BRCA1	P38398-1.2	E1053M	Neutral	0.35
BRCA1	P38398-1.2	E1053N	Neutral	0.205
BRCA1	P38398-1.2	E1053P	Neutral	0.292
BRCA1	P38398-1.2	E1053Q	Neutral	0.094
BRCA1	P38398-1.2	E1053R	Neutral	0.313
BRCA1	P38398-1.2	E1053S	Neutral	0.298
BRCA1	P38398-1.2	E1053T	Neutral	0.28
BRCA1	P38398-1.2	E1053V	Neutral	0.296
BRCA1	P38398-1.2	E1053W	Pathogenic	0.643
BRCA1	P38398-1.2	E1053Y	Neutral	0.441
BRCA1	P38398-1.2	V1054A	Neutral	0.05
BRCA1	P38398-1.2	V1054C	Neutral	0.048
BRCA1	P38398-1.2	V1054D	Neutral	0.082
BRCA1	P38398-1.2	V1054E	Neutral	0.048
BRCA1	P38398-1.2	V1054F	Neutral	0.06
BRCA1	P38398-1.2	V1054G	Neutral	0.191
BRCA1	P38398-1.2	V1054H	Neutral	0.082
BRCA1	P38398-1.2	V1054I	Neutral	0.011
BRCA1	P38398-1.2	V1054K	Neutral	0.081
BRCA1	P38398-1.2	V1054L	Neutral	0.023
BRCA1	P38398-1.2	V1054M	Neutral	0.024
BRCA1	P38398-1.2	V1054N	Neutral	0.074
BRCA1	P38398-1.2	V1054P	Neutral	0.061
BRCA1	P38398-1.2	V1054Q	Neutral	0.053
BRCA1	P38398-1.2	V1054R	Neutral	0.145
BRCA1	P38398-1.2	V1054S	Neutral	0.086
BRCA1	P38398-1.2	V1054T	Neutral	0.028
BRCA1	P38398-1.2	V1054W	Neutral	0.195
BRCA1	P38398-1.2	V1054Y	Neutral	0.068
BRCA1	P38398-1.2	G1055A	Neutral	0.441
BRCA1	P38398-1.2	G1055C	Pathogenic	0.78
BRCA1	P38398-1.2	G1055D	Pathogenic	0.657
BRCA1	P38398-1.2	G1055E	Pathogenic	0.805
BRCA1	P38398-1.2	G1055F	Pathogenic	0.912
BRCA1	P38398-1.2	G1055H	Pathogenic	0.836
BRCA1	P38398-1.2	G1055I	Pathogenic	0.921
BRCA1	P38398-1.2	G1055K	Pathogenic	0.879
BRCA1	P38398-1.2	G1055L	Pathogenic	0.921
BRCA1	P38398-1.2	G1055M	Pathogenic	0.891
BRCA1	P38398-1.2	G1055N	Pathogenic	0.599
BRCA1	P38398-1.2	G1055P	Pathogenic	0.73
BRCA1	P38398-1.2	G1055Q	Pathogenic	0.823
BRCA1	P38398-1.2	G1055R	Pathogenic	0.907
BRCA1	P38398-1.2	G1055S	Neutral	0.475
BRCA1	P38398-1.2	G1055T	Pathogenic	0.744
BRCA1	P38398-1.2	G1055V	Pathogenic	0.843
BRCA1	P38398-1.2	G1055W	Pathogenic	0.93
BRCA1	P38398-1.2	G1055Y	Pathogenic	0.923
BRCA1	P38398-1.2	S1056A	Pathogenic	0.559
BRCA1	P38398-1.2	S1056C	Pathogenic	0.752
BRCA1	P38398-1.2	S1056D	Pathogenic	0.703
BRCA1	P38398-1.2	S1056E	Pathogenic	0.78
BRCA1	P38398-1.2	S1056F	Pathogenic	0.927
BRCA1	P38398-1.2	S1056G	Pathogenic	0.737
BRCA1	P38398-1.2	S1056H	Pathogenic	0.862
BRCA1	P38398-1.2	S1056I	Pathogenic	0.909
BRCA1	P38398-1.2	S1056K	Pathogenic	0.862
BRCA1	P38398-1.2	S1056L	Pathogenic	0.909
BRCA1	P38398-1.2	S1056M	Pathogenic	0.875
BRCA1	P38398-1.2	S1056N	Pathogenic	0.648
BRCA1	P38398-1.2	S1056P	Pathogenic	0.769
BRCA1	P38398-1.2	S1056Q	Pathogenic	0.799
BRCA1	P38398-1.2	S1056R	Pathogenic	0.923
BRCA1	P38398-1.2	S1056T	Pathogenic	0.634
BRCA1	P38398-1.2	S1056V	Pathogenic	0.869
BRCA1	P38398-1.2	S1056W	Pathogenic	0.971
BRCA1	P38398-1.2	S1056Y	Pathogenic	0.937
BRCA1	P38398-1.2	S1057A	Neutral	0.285
BRCA1	P38398-1.2	S1057C	Neutral	0.488
BRCA1	P38398-1.2	S1057D	Neutral	0.427
BRCA1	P38398-1.2	S1057E	Pathogenic	0.527
BRCA1	P38398-1.2	S1057F	Pathogenic	0.8
BRCA1	P38398-1.2	S1057G	Neutral	0.468
BRCA1	P38398-1.2	S1057H	Pathogenic	0.664
BRCA1	P38398-1.2	S1057I	Pathogenic	0.759
BRCA1	P38398-1.2	S1057K	Pathogenic	0.663
BRCA1	P38398-1.2	S1057L	Pathogenic	0.759
BRCA1	P38398-1.2	S1057M	Pathogenic	0.688
BRCA1	P38398-1.2	S1057N	Neutral	0.367
BRCA1	P38398-1.2	S1057P	Pathogenic	0.512
BRCA1	P38398-1.2	S1057Q	Pathogenic	0.556
BRCA1	P38398-1.2	S1057R	Pathogenic	0.791
BRCA1	P38398-1.2	S1057T	Neutral	0.353
BRCA1	P38398-1.2	S1057V	Pathogenic	0.676
BRCA1	P38398-1.2	S1057W	Pathogenic	0.914
BRCA1	P38398-1.2	S1057Y	Pathogenic	0.823
BRCA1	P38398-1.2	I1058A	Neutral	0.091
BRCA1	P38398-1.2	I1058C	Neutral	0.062
BRCA1	P38398-1.2	I1058D	Neutral	0.107
BRCA1	P38398-1.2	I1058E	Neutral	0.074
BRCA1	P38398-1.2	I1058F	Neutral	0.025
BRCA1	P38398-1.2	I1058G	Neutral	0.312
BRCA1	P38398-1.2	I1058H	Neutral	0.063
BRCA1	P38398-1.2	I1058K	Neutral	0.068
BRCA1	P38398-1.2	I1058L	Neutral	0.01
BRCA1	P38398-1.2	I1058M	Neutral	0.014
BRCA1	P38398-1.2	I1058N	Neutral	0.097
BRCA1	P38398-1.2	I1058P	Neutral	0.112
BRCA1	P38398-1.2	I1058Q	Neutral	0.067
BRCA1	P38398-1.2	I1058R	Neutral	0.089
BRCA1	P38398-1.2	I1058S	Neutral	0.111
BRCA1	P38398-1.2	I1058T	Neutral	0.053
BRCA1	P38398-1.2	I1058V	Neutral	0.01
BRCA1	P38398-1.2	I1058W	Neutral	0.124
BRCA1	P38398-1.2	I1058Y	Neutral	0.04
BRCA1	P38398-1.2	N1059A	Pathogenic	0.917
BRCA1	P38398-1.2	N1059C	Pathogenic	0.911
BRCA1	P38398-1.2	N1059D	Pathogenic	0.687
BRCA1	P38398-1.2	N1059E	Pathogenic	0.791
BRCA1	P38398-1.2	N1059F	Pathogenic	0.95
BRCA1	P38398-1.2	N1059G	Pathogenic	0.891
BRCA1	P38398-1.2	N1059H	Pathogenic	0.76
BRCA1	P38398-1.2	N1059I	Pathogenic	0.938
BRCA1	P38398-1.2	N1059K	Pathogenic	0.87
BRCA1	P38398-1.2	N1059L	Pathogenic	0.938
BRCA1	P38398-1.2	N1059M	Pathogenic	0.913
BRCA1	P38398-1.2	N1059P	Pathogenic	0.867
BRCA1	P38398-1.2	N1059Q	Pathogenic	0.808
BRCA1	P38398-1.2	N1059R	Pathogenic	0.899
BRCA1	P38398-1.2	N1059S	Pathogenic	0.765
BRCA1	P38398-1.2	N1059T	Pathogenic	0.749
BRCA1	P38398-1.2	N1059V	Pathogenic	0.909
BRCA1	P38398-1.2	N1059W	Pathogenic	0.981
BRCA1	P38398-1.2	N1059Y	Pathogenic	0.939
BRCA1	P38398-1.2	E1060A	Pathogenic	0.981
BRCA1	P38398-1.2	E1060C	Pathogenic	0.99
BRCA1	P38398-1.2	E1060D	Pathogenic	0.911
BRCA1	P38398-1.2	E1060F	Pathogenic	0.986
BRCA1	P38398-1.2	E1060G	Pathogenic	0.991
BRCA1	P38398-1.2	E1060H	Pathogenic	0.945
BRCA1	P38398-1.2	E1060I	Pathogenic	0.983
BRCA1	P38398-1.2	E1060K	Pathogenic	0.946
BRCA1	P38398-1.2	E1060L	Pathogenic	0.983
BRCA1	P38398-1.2	E1060M	Pathogenic	0.976
BRCA1	P38398-1.2	E1060N	Pathogenic	0.95
BRCA1	P38398-1.2	E1060P	Pathogenic	0.968
BRCA1	P38398-1.2	E1060Q	Pathogenic	0.884
BRCA1	P38398-1.2	E1060R	Pathogenic	0.971
BRCA1	P38398-1.2	E1060S	Pathogenic	0.969
BRCA1	P38398-1.2	E1060T	Pathogenic	0.967
BRCA1	P38398-1.2	E1060V	Pathogenic	0.969
BRCA1	P38398-1.2	E1060W	Pathogenic	0.993
BRCA1	P38398-1.2	E1060Y	Pathogenic	0.983
BRCA1	P38398-1.2	I1061A	Pathogenic	0.887
BRCA1	P38398-1.2	I1061C	Pathogenic	0.839
BRCA1	P38398-1.2	I1061D	Pathogenic	0.903
BRCA1	P38398-1.2	I1061E	Pathogenic	0.862
BRCA1	P38398-1.2	I1061F	Pathogenic	0.668
BRCA1	P38398-1.2	I1061G	Pathogenic	0.973
BRCA1	P38398-1.2	I1061H	Pathogenic	0.839
BRCA1	P38398-1.2	I1061K	Pathogenic	0.851
BRCA1	P38398-1.2	I1061L	Neutral	0.432
BRCA1	P38398-1.2	I1061M	Pathogenic	0.521
BRCA1	P38398-1.2	I1061N	Pathogenic	0.893
BRCA1	P38398-1.2	I1061P	Pathogenic	0.908
BRCA1	P38398-1.2	I1061Q	Pathogenic	0.85
BRCA1	P38398-1.2	I1061R	Pathogenic	0.884
BRCA1	P38398-1.2	I1061S	Pathogenic	0.907
BRCA1	P38398-1.2	I1061T	Pathogenic	0.815
BRCA1	P38398-1.2	I1061V	Neutral	0.444
BRCA1	P38398-1.2	I1061W	Pathogenic	0.917
BRCA1	P38398-1.2	I1061Y	Pathogenic	0.765
BRCA1	P38398-1.2	G1062A	Neutral	0.46
BRCA1	P38398-1.2	G1062C	Pathogenic	0.793
BRCA1	P38398-1.2	G1062D	Pathogenic	0.674
BRCA1	P38398-1.2	G1062E	Pathogenic	0.817
BRCA1	P38398-1.2	G1062F	Pathogenic	0.918
BRCA1	P38398-1.2	G1062H	Pathogenic	0.846
BRCA1	P38398-1.2	G1062I	Pathogenic	0.926
BRCA1	P38398-1.2	G1062K	Pathogenic	0.887
BRCA1	P38398-1.2	G1062L	Pathogenic	0.927
BRCA1	P38398-1.2	G1062M	Pathogenic	0.898
BRCA1	P38398-1.2	G1062N	Pathogenic	0.617
BRCA1	P38398-1.2	G1062P	Pathogenic	0.745
BRCA1	P38398-1.2	G1062Q	Pathogenic	0.834
BRCA1	P38398-1.2	G1062R	Pathogenic	0.913
BRCA1	P38398-1.2	G1062S	Neutral	0.495
BRCA1	P38398-1.2	G1062T	Pathogenic	0.759
BRCA1	P38398-1.2	G1062V	Pathogenic	0.853
BRCA1	P38398-1.2	G1062W	Pathogenic	0.935
BRCA1	P38398-1.2	G1062Y	Pathogenic	0.928
BRCA1	P38398-1.2	S1063A	Pathogenic	0.87
BRCA1	P38398-1.2	S1063C	Pathogenic	0.941
BRCA1	P38398-1.2	S1063D	Pathogenic	0.926
BRCA1	P38398-1.2	S1063E	Pathogenic	0.949
BRCA1	P38398-1.2	S1063F	Pathogenic	0.985
BRCA1	P38398-1.2	S1063G	Pathogenic	0.937
BRCA1	P38398-1.2	S1063H	Pathogenic	0.971
BRCA1	P38398-1.2	S1063I	Pathogenic	0.981
BRCA1	P38398-1.2	S1063K	Pathogenic	0.971
BRCA1	P38398-1.2	S1063L	Pathogenic	0.981
BRCA1	P38398-1.2	S1063M	Pathogenic	0.974
BRCA1	P38398-1.2	S1063N	Pathogenic	0.907
BRCA1	P38398-1.2	S1063P	Pathogenic	0.946
BRCA1	P38398-1.2	S1063Q	Pathogenic	0.955
BRCA1	P38398-1.2	S1063R	Pathogenic	0.985
BRCA1	P38398-1.2	S1063T	Pathogenic	0.902
BRCA1	P38398-1.2	S1063V	Pathogenic	0.972
BRCA1	P38398-1.2	S1063W	Pathogenic	0.994
BRCA1	P38398-1.2	S1063Y	Pathogenic	0.987
BRCA1	P38398-1.2	S1064A	Pathogenic	0.698
BRCA1	P38398-1.2	S1064C	Pathogenic	0.846
BRCA1	P38398-1.2	S1064D	Pathogenic	0.811
BRCA1	P38398-1.2	S1064E	Pathogenic	0.866
BRCA1	P38398-1.2	S1064F	Pathogenic	0.959
BRCA1	P38398-1.2	S1064G	Pathogenic	0.836
BRCA1	P38398-1.2	S1064H	Pathogenic	0.919
BRCA1	P38398-1.2	S1064I	Pathogenic	0.948
BRCA1	P38398-1.2	S1064K	Pathogenic	0.919
BRCA1	P38398-1.2	S1064L	Pathogenic	0.948
BRCA1	P38398-1.2	S1064M	Pathogenic	0.927
BRCA1	P38398-1.2	S1064N	Pathogenic	0.77
BRCA1	P38398-1.2	S1064P	Pathogenic	0.858
BRCA1	P38398-1.2	S1064Q	Pathogenic	0.879
BRCA1	P38398-1.2	S1064R	Pathogenic	0.956
BRCA1	P38398-1.2	S1064T	Pathogenic	0.759
BRCA1	P38398-1.2	S1064V	Pathogenic	0.923
BRCA1	P38398-1.2	S1064W	Pathogenic	0.984
BRCA1	P38398-1.2	S1064Y	Pathogenic	0.964
BRCA1	P38398-1.2	D1065A	Neutral	0.268
BRCA1	P38398-1.2	D1065C	Neutral	0.254
BRCA1	P38398-1.2	D1065E	Neutral	0.071
BRCA1	P38398-1.2	D1065F	Neutral	0.444
BRCA1	P38398-1.2	D1065G	Neutral	0.281
BRCA1	P38398-1.2	D1065H	Neutral	0.214
BRCA1	P38398-1.2	D1065I	Neutral	0.385
BRCA1	P38398-1.2	D1065K	Neutral	0.287
BRCA1	P38398-1.2	D1065L	Neutral	0.474
BRCA1	P38398-1.2	D1065M	Neutral	0.387
BRCA1	P38398-1.2	D1065N	Neutral	0.076
BRCA1	P38398-1.2	D1065P	Neutral	0.132
BRCA1	P38398-1.2	D1065Q	Neutral	0.149
BRCA1	P38398-1.2	D1065R	Neutral	0.436
BRCA1	P38398-1.2	D1065S	Neutral	0.135
BRCA1	P38398-1.2	D1065T	Neutral	0.135
BRCA1	P38398-1.2	D1065V	Neutral	0.293
BRCA1	P38398-1.2	D1065W	Pathogenic	0.68
BRCA1	P38398-1.2	D1065Y	Neutral	0.481
BRCA1	P38398-1.2	E1066A	Pathogenic	0.955
BRCA1	P38398-1.2	E1066C	Pathogenic	0.976
BRCA1	P38398-1.2	E1066D	Pathogenic	0.809
BRCA1	P38398-1.2	E1066F	Pathogenic	0.968
BRCA1	P38398-1.2	E1066G	Pathogenic	0.979
BRCA1	P38398-1.2	E1066H	Pathogenic	0.876
BRCA1	P38398-1.2	E1066I	Pathogenic	0.959
BRCA1	P38398-1.2	E1066K	Pathogenic	0.879
BRCA1	P38398-1.2	E1066L	Pathogenic	0.959
BRCA1	P38398-1.2	E1066M	Pathogenic	0.943
BRCA1	P38398-1.2	E1066N	Pathogenic	0.887
BRCA1	P38398-1.2	E1066P	Pathogenic	0.926
BRCA1	P38398-1.2	E1066Q	Pathogenic	0.759
BRCA1	P38398-1.2	E1066R	Pathogenic	0.933
BRCA1	P38398-1.2	E1066S	Pathogenic	0.928
BRCA1	P38398-1.2	E1066T	Pathogenic	0.922
BRCA1	P38398-1.2	E1066V	Pathogenic	0.928
BRCA1	P38398-1.2	E1066W	Pathogenic	0.982
BRCA1	P38398-1.2	E1066Y	Pathogenic	0.96
BRCA1	P38398-1.2	N1067A	Pathogenic	0.589
BRCA1	P38398-1.2	N1067C	Pathogenic	0.572
BRCA1	P38398-1.2	N1067D	Neutral	0.223
BRCA1	P38398-1.2	N1067E	Neutral	0.331
BRCA1	P38398-1.2	N1067F	Pathogenic	0.715
BRCA1	P38398-1.2	N1067G	Pathogenic	0.515
BRCA1	P38398-1.2	N1067H	Neutral	0.293
BRCA1	P38398-1.2	N1067I	Pathogenic	0.662
BRCA1	P38398-1.2	N1067K	Neutral	0.466
BRCA1	P38398-1.2	N1067L	Pathogenic	0.663
BRCA1	P38398-1.2	N1067M	Pathogenic	0.58
BRCA1	P38398-1.2	N1067P	Neutral	0.461
BRCA1	P38398-1.2	N1067Q	Neutral	0.354
BRCA1	P38398-1.2	N1067R	Pathogenic	0.538
BRCA1	P38398-1.2	N1067S	Neutral	0.298
BRCA1	P38398-1.2	N1067T	Neutral	0.28
BRCA1	P38398-1.2	N1067V	Pathogenic	0.566
BRCA1	P38398-1.2	N1067W	Pathogenic	0.869
BRCA1	P38398-1.2	N1067Y	Pathogenic	0.669
BRCA1	P38398-1.2	I1068A	Neutral	0.098
BRCA1	P38398-1.2	I1068C	Neutral	0.067
BRCA1	P38398-1.2	I1068D	Neutral	0.115
BRCA1	P38398-1.2	I1068E	Neutral	0.08
BRCA1	P38398-1.2	I1068F	Neutral	0.027
BRCA1	P38398-1.2	I1068G	Neutral	0.33
BRCA1	P38398-1.2	I1068H	Neutral	0.067
BRCA1	P38398-1.2	I1068K	Neutral	0.073
BRCA1	P38398-1.2	I1068L	Neutral	0.01
BRCA1	P38398-1.2	I1068M	Neutral	0.015
BRCA1	P38398-1.2	I1068N	Neutral	0.104
BRCA1	P38398-1.2	I1068P	Neutral	0.12
BRCA1	P38398-1.2	I1068Q	Neutral	0.073
BRCA1	P38398-1.2	I1068R	Neutral	0.096
BRCA1	P38398-1.2	I1068S	Neutral	0.12
BRCA1	P38398-1.2	I1068T	Neutral	0.058
BRCA1	P38398-1.2	I1068V	Neutral	0.011
BRCA1	P38398-1.2	I1068W	Neutral	0.134
BRCA1	P38398-1.2	I1068Y	Neutral	0.043
BRCA1	P38398-1.2	Q1069A	Pathogenic	0.795
BRCA1	P38398-1.2	Q1069C	Pathogenic	0.838
BRCA1	P38398-1.2	Q1069D	Pathogenic	0.612
BRCA1	P38398-1.2	Q1069E	Neutral	0.339
BRCA1	P38398-1.2	Q1069F	Pathogenic	0.814
BRCA1	P38398-1.2	Q1069G	Pathogenic	0.895
BRCA1	P38398-1.2	Q1069H	Pathogenic	0.509
BRCA1	P38398-1.2	Q1069I	Pathogenic	0.774
BRCA1	P38398-1.2	Q1069K	Pathogenic	0.511
BRCA1	P38398-1.2	Q1069L	Pathogenic	0.704
BRCA1	P38398-1.2	Q1069M	Pathogenic	0.537
BRCA1	P38398-1.2	Q1069N	Pathogenic	0.586
BRCA1	P38398-1.2	Q1069P	Pathogenic	0.697
BRCA1	P38398-1.2	Q1069R	Pathogenic	0.582
BRCA1	P38398-1.2	Q1069S	Pathogenic	0.703
BRCA1	P38398-1.2	Q1069T	Pathogenic	0.685
BRCA1	P38398-1.2	Q1069V	Pathogenic	0.702
BRCA1	P38398-1.2	Q1069W	Pathogenic	0.849
BRCA1	P38398-1.2	Q1069Y	Pathogenic	0.71
BRCA1	P38398-1.2	A1070C	Pathogenic	0.653
BRCA1	P38398-1.2	A1070D	Pathogenic	0.812
BRCA1	P38398-1.2	A1070E	Pathogenic	0.818
BRCA1	P38398-1.2	A1070F	Pathogenic	0.919
BRCA1	P38398-1.2	A1070G	Pathogenic	0.655
BRCA1	P38398-1.2	A1070H	Pathogenic	0.889
BRCA1	P38398-1.2	A1070I	Pathogenic	0.861
BRCA1	P38398-1.2	A1070K	Pathogenic	0.888
BRCA1	P38398-1.2	A1070L	Pathogenic	0.861
BRCA1	P38398-1.2	A1070M	Pathogenic	0.863
BRCA1	P38398-1.2	A1070N	Pathogenic	0.829
BRCA1	P38398-1.2	A1070P	Pathogenic	0.749
BRCA1	P38398-1.2	A1070Q	Pathogenic	0.835
BRCA1	P38398-1.2	A1070R	Pathogenic	0.914
BRCA1	P38398-1.2	A1070S	Neutral	0.497
BRCA1	P38398-1.2	A1070T	Pathogenic	0.69
BRCA1	P38398-1.2	A1070V	Pathogenic	0.741
BRCA1	P38398-1.2	A1070W	Pathogenic	0.968
BRCA1	P38398-1.2	A1070Y	Pathogenic	0.93
BRCA1	P38398-1.2	E1071A	Pathogenic	0.615
BRCA1	P38398-1.2	E1071C	Pathogenic	0.755
BRCA1	P38398-1.2	E1071D	Neutral	0.242
BRCA1	P38398-1.2	E1071F	Pathogenic	0.692
BRCA1	P38398-1.2	E1071G	Pathogenic	0.779
BRCA1	P38398-1.2	E1071H	Neutral	0.348
BRCA1	P38398-1.2	E1071I	Pathogenic	0.638
BRCA1	P38398-1.2	E1071K	Neutral	0.353
BRCA1	P38398-1.2	E1071L	Pathogenic	0.639
BRCA1	P38398-1.2	E1071M	Pathogenic	0.553
BRCA1	P38398-1.2	E1071N	Neutral	0.372
BRCA1	P38398-1.2	E1071P	Neutral	0.487
BRCA1	P38398-1.2	E1071Q	Neutral	0.192
BRCA1	P38398-1.2	E1071R	Pathogenic	0.512
BRCA1	P38398-1.2	E1071S	Neutral	0.494
BRCA1	P38398-1.2	E1071T	Neutral	0.473
BRCA1	P38398-1.2	E1071V	Neutral	0.493
BRCA1	P38398-1.2	E1071W	Pathogenic	0.806
BRCA1	P38398-1.2	E1071Y	Pathogenic	0.645
BRCA1	P38398-1.2	L1072A	Neutral	0.096
BRCA1	P38398-1.2	L1072C	Neutral	0.066
BRCA1	P38398-1.2	L1072D	Neutral	0.154
BRCA1	P38398-1.2	L1072E	Neutral	0.079
BRCA1	P38398-1.2	L1072F	Neutral	0.027
BRCA1	P38398-1.2	L1072G	Neutral	0.325
BRCA1	P38398-1.2	L1072H	Neutral	0.066
BRCA1	P38398-1.2	L1072I	Neutral	0.01
BRCA1	P38398-1.2	L1072K	Neutral	0.051
BRCA1	P38398-1.2	L1072M	Neutral	0.01
BRCA1	P38398-1.2	L1072N	Neutral	0.102
BRCA1	P38398-1.2	L1072P	Neutral	0.118
BRCA1	P38398-1.2	L1072Q	Neutral	0.051
BRCA1	P38398-1.2	L1072R	Neutral	0.067
BRCA1	P38398-1.2	L1072S	Neutral	0.118
BRCA1	P38398-1.2	L1072T	Neutral	0.056
BRCA1	P38398-1.2	L1072V	Neutral	0.022
BRCA1	P38398-1.2	L1072W	Neutral	0.095
BRCA1	P38398-1.2	L1072Y	Neutral	0.043
BRCA1	P38398-1.2	G1073A	Neutral	0.153
BRCA1	P38398-1.2	G1073C	Neutral	0.447
BRCA1	P38398-1.2	G1073D	Neutral	0.305
BRCA1	P38398-1.2	G1073E	Neutral	0.485
BRCA1	P38398-1.2	G1073F	Pathogenic	0.703
BRCA1	P38398-1.2	G1073H	Pathogenic	0.538
BRCA1	P38398-1.2	G1073I	Pathogenic	0.727
BRCA1	P38398-1.2	G1073K	Pathogenic	0.625
BRCA1	P38398-1.2	G1073L	Pathogenic	0.728
BRCA1	P38398-1.2	G1073M	Pathogenic	0.652
BRCA1	P38398-1.2	G1073N	Neutral	0.255
BRCA1	P38398-1.2	G1073P	Neutral	0.382
BRCA1	P38398-1.2	G1073Q	Pathogenic	0.515
BRCA1	P38398-1.2	G1073R	Pathogenic	0.69
BRCA1	P38398-1.2	G1073S	Neutral	0.172
BRCA1	P38398-1.2	G1073T	Neutral	0.4
BRCA1	P38398-1.2	G1073V	Pathogenic	0.551
BRCA1	P38398-1.2	G1073W	Pathogenic	0.752
BRCA1	P38398-1.2	G1073Y	Pathogenic	0.733
BRCA1	P38398-1.2	R1074A	Pathogenic	0.866
BRCA1	P38398-1.2	R1074C	Pathogenic	0.896
BRCA1	P38398-1.2	R1074D	Pathogenic	0.848
BRCA1	P38398-1.2	R1074E	Pathogenic	0.642
BRCA1	P38398-1.2	R1074F	Pathogenic	0.741
BRCA1	P38398-1.2	R1074G	Pathogenic	0.934
BRCA1	P38398-1.2	R1074H	Pathogenic	0.592
BRCA1	P38398-1.2	R1074I	Pathogenic	0.785
BRCA1	P38398-1.2	R1074K	Neutral	0.329
BRCA1	P38398-1.2	R1074L	Pathogenic	0.718
BRCA1	P38398-1.2	R1074M	Pathogenic	0.641
BRCA1	P38398-1.2	R1074N	Pathogenic	0.706
BRCA1	P38398-1.2	R1074P	Pathogenic	0.847
BRCA1	P38398-1.2	R1074Q	Pathogenic	0.526
BRCA1	P38398-1.2	R1074S	Pathogenic	0.85
BRCA1	P38398-1.2	R1074T	Pathogenic	0.784
BRCA1	P38398-1.2	R1074V	Pathogenic	0.85
BRCA1	P38398-1.2	R1074W	Pathogenic	0.748
BRCA1	P38398-1.2	R1074Y	Pathogenic	0.639
BRCA1	P38398-1.2	N1075A	Neutral	0.33
BRCA1	P38398-1.2	N1075C	Neutral	0.315
BRCA1	P38398-1.2	N1075D	Neutral	0.09
BRCA1	P38398-1.2	N1075E	Neutral	0.145
BRCA1	P38398-1.2	N1075F	Neutral	0.463
BRCA1	P38398-1.2	N1075G	Neutral	0.268
BRCA1	P38398-1.2	N1075H	Neutral	0.125
BRCA1	P38398-1.2	N1075I	Neutral	0.403
BRCA1	P38398-1.2	N1075K	Neutral	0.231
BRCA1	P38398-1.2	N1075L	Neutral	0.403
BRCA1	P38398-1.2	N1075M	Neutral	0.322
BRCA1	P38398-1.2	N1075P	Neutral	0.227
BRCA1	P38398-1.2	N1075Q	Neutral	0.159
BRCA1	P38398-1.2	N1075R	Neutral	0.286
BRCA1	P38398-1.2	N1075S	Neutral	0.127
BRCA1	P38398-1.2	N1075T	Neutral	0.118
BRCA1	P38398-1.2	N1075V	Neutral	0.309
BRCA1	P38398-1.2	N1075W	Pathogenic	0.696
BRCA1	P38398-1.2	N1075Y	Neutral	0.41
BRCA1	P38398-1.2	R1076A	Pathogenic	0.946
BRCA1	P38398-1.2	R1076C	Pathogenic	0.959
BRCA1	P38398-1.2	R1076D	Pathogenic	0.937
BRCA1	P38398-1.2	R1076E	Pathogenic	0.829
BRCA1	P38398-1.2	R1076F	Pathogenic	0.885
BRCA1	P38398-1.2	R1076G	Pathogenic	0.975
BRCA1	P38398-1.2	R1076H	Pathogenic	0.796
BRCA1	P38398-1.2	R1076I	Pathogenic	0.908
BRCA1	P38398-1.2	R1076K	Pathogenic	0.569
BRCA1	P38398-1.2	R1076L	Pathogenic	0.873
BRCA1	P38398-1.2	R1076M	Pathogenic	0.828
BRCA1	P38398-1.2	R1076N	Pathogenic	0.866
BRCA1	P38398-1.2	R1076P	Pathogenic	0.937
BRCA1	P38398-1.2	R1076Q	Pathogenic	0.749
BRCA1	P38398-1.2	R1076S	Pathogenic	0.939
BRCA1	P38398-1.2	R1076T	Pathogenic	0.907
BRCA1	P38398-1.2	R1076V	Pathogenic	0.938
BRCA1	P38398-1.2	R1076W	Pathogenic	0.889
BRCA1	P38398-1.2	R1076Y	Pathogenic	0.827
BRCA1	P38398-1.2	G1077A	Neutral	0.4
BRCA1	P38398-1.2	G1077C	Pathogenic	0.749
BRCA1	P38398-1.2	G1077D	Pathogenic	0.618
BRCA1	P38398-1.2	G1077E	Pathogenic	0.777
BRCA1	P38398-1.2	G1077F	Pathogenic	0.897
BRCA1	P38398-1.2	G1077H	Pathogenic	0.811
BRCA1	P38398-1.2	G1077I	Pathogenic	0.908
BRCA1	P38398-1.2	G1077K	Pathogenic	0.86
BRCA1	P38398-1.2	G1077L	Pathogenic	0.908
BRCA1	P38398-1.2	G1077M	Pathogenic	0.874
BRCA1	P38398-1.2	G1077N	Pathogenic	0.558
BRCA1	P38398-1.2	G1077P	Pathogenic	0.695
BRCA1	P38398-1.2	G1077Q	Pathogenic	0.797
BRCA1	P38398-1.2	G1077R	Pathogenic	0.892
BRCA1	P38398-1.2	G1077S	Neutral	0.433
BRCA1	P38398-1.2	G1077T	Pathogenic	0.711
BRCA1	P38398-1.2	G1077V	Pathogenic	0.819
BRCA1	P38398-1.2	G1077W	Pathogenic	0.918
BRCA1	P38398-1.2	G1077Y	Pathogenic	0.91
BRCA1	P38398-1.2	P1078A	Pathogenic	0.534
BRCA1	P38398-1.2	P1078C	Pathogenic	0.61
BRCA1	P38398-1.2	P1078D	Neutral	0.408
BRCA1	P38398-1.2	P1078E	Pathogenic	0.508
BRCA1	P38398-1.2	P1078F	Pathogenic	0.846
BRCA1	P38398-1.2	P1078G	Pathogenic	0.715
BRCA1	P38398-1.2	P1078H	Pathogenic	0.648
BRCA1	P38398-1.2	P1078I	Pathogenic	0.75
BRCA1	P38398-1.2	P1078K	Pathogenic	0.646
BRCA1	P38398-1.2	P1078L	Pathogenic	0.75
BRCA1	P38398-1.2	P1078M	Pathogenic	0.678
BRCA1	P38398-1.2	P1078N	Pathogenic	0.527
BRCA1	P38398-1.2	P1078Q	Pathogenic	0.537
BRCA1	P38398-1.2	P1078R	Pathogenic	0.778
BRCA1	P38398-1.2	P1078S	Neutral	0.5
BRCA1	P38398-1.2	P1078T	Neutral	0.424
BRCA1	P38398-1.2	P1078V	Pathogenic	0.58
BRCA1	P38398-1.2	P1078W	Pathogenic	0.91
BRCA1	P38398-1.2	P1078Y	Pathogenic	0.816
BRCA1	P38398-1.2	K1079A	Neutral	0.318
BRCA1	P38398-1.2	K1079C	Neutral	0.384
BRCA1	P38398-1.2	K1079D	Neutral	0.218
BRCA1	P38398-1.2	K1079E	Neutral	0.083
BRCA1	P38398-1.2	K1079F	Neutral	0.172
BRCA1	P38398-1.2	K1079G	Pathogenic	0.507
BRCA1	P38398-1.2	K1079H	Neutral	0.131
BRCA1	P38398-1.2	K1079I	Neutral	0.209
BRCA1	P38398-1.2	K1079L	Neutral	0.155
BRCA1	P38398-1.2	K1079M	Neutral	0.114
BRCA1	P38398-1.2	K1079N	Neutral	0.147
BRCA1	P38398-1.2	K1079P	Neutral	0.217
BRCA1	P38398-1.2	K1079Q	Neutral	0.074
BRCA1	P38398-1.2	K1079R	Neutral	0.045
BRCA1	P38398-1.2	K1079S	Neutral	0.222
BRCA1	P38398-1.2	K1079T	Neutral	0.207
BRCA1	P38398-1.2	K1079V	Neutral	0.221
BRCA1	P38398-1.2	K1079W	Neutral	0.277
BRCA1	P38398-1.2	K1079Y	Neutral	0.143
BRCA1	P38398-1.2	L1080A	Pathogenic	0.964
BRCA1	P38398-1.2	L1080C	Pathogenic	0.947
BRCA1	P38398-1.2	L1080D	Pathogenic	0.979
BRCA1	P38398-1.2	L1080E	Pathogenic	0.956
BRCA1	P38398-1.2	L1080F	Pathogenic	0.874
BRCA1	P38398-1.2	L1080G	Pathogenic	0.992
BRCA1	P38398-1.2	L1080H	Pathogenic	0.947
BRCA1	P38398-1.2	L1080I	Pathogenic	0.723
BRCA1	P38398-1.2	L1080K	Pathogenic	0.932
BRCA1	P38398-1.2	L1080M	Pathogenic	0.722
BRCA1	P38398-1.2	L1080N	Pathogenic	0.966
BRCA1	P38398-1.2	L1080P	Pathogenic	0.971
BRCA1	P38398-1.2	L1080Q	Pathogenic	0.931
BRCA1	P38398-1.2	L1080R	Pathogenic	0.948
BRCA1	P38398-1.2	L1080S	Pathogenic	0.971
BRCA1	P38398-1.2	L1080T	Pathogenic	0.938
BRCA1	P38398-1.2	L1080V	Pathogenic	0.851
BRCA1	P38398-1.2	L1080W	Pathogenic	0.964
BRCA1	P38398-1.2	L1080Y	Pathogenic	0.918
BRCA1	P38398-1.2	N1081A	Neutral	0.313
BRCA1	P38398-1.2	N1081C	Neutral	0.297
BRCA1	P38398-1.2	N1081D	Neutral	0.083
BRCA1	P38398-1.2	N1081E	Neutral	0.135
BRCA1	P38398-1.2	N1081F	Neutral	0.443
BRCA1	P38398-1.2	N1081G	Neutral	0.252
BRCA1	P38398-1.2	N1081H	Neutral	0.116
BRCA1	P38398-1.2	N1081I	Neutral	0.383
BRCA1	P38398-1.2	N1081K	Neutral	0.217
BRCA1	P38398-1.2	N1081L	Neutral	0.384
BRCA1	P38398-1.2	N1081M	Neutral	0.304
BRCA1	P38398-1.2	N1081P	Neutral	0.213
BRCA1	P38398-1.2	N1081Q	Neutral	0.148
BRCA1	P38398-1.2	N1081R	Neutral	0.27
BRCA1	P38398-1.2	N1081S	Neutral	0.118
BRCA1	P38398-1.2	N1081T	Neutral	0.11
BRCA1	P38398-1.2	N1081V	Neutral	0.292
BRCA1	P38398-1.2	N1081W	Pathogenic	0.678
BRCA1	P38398-1.2	N1081Y	Neutral	0.39
BRCA1	P38398-1.2	A1082C	Pathogenic	0.53
BRCA1	P38398-1.2	A1082D	Pathogenic	0.721
BRCA1	P38398-1.2	A1082E	Pathogenic	0.729
BRCA1	P38398-1.2	A1082F	Pathogenic	0.872
BRCA1	P38398-1.2	A1082G	Pathogenic	0.532
BRCA1	P38398-1.2	A1082H	Pathogenic	0.827
BRCA1	P38398-1.2	A1082I	Pathogenic	0.788
BRCA1	P38398-1.2	A1082K	Pathogenic	0.826
BRCA1	P38398-1.2	A1082L	Pathogenic	0.788
BRCA1	P38398-1.2	A1082M	Pathogenic	0.79
BRCA1	P38398-1.2	A1082N	Pathogenic	0.744
BRCA1	P38398-1.2	A1082P	Pathogenic	0.64
BRCA1	P38398-1.2	A1082Q	Pathogenic	0.752
BRCA1	P38398-1.2	A1082R	Pathogenic	0.864
BRCA1	P38398-1.2	A1082S	Neutral	0.371
BRCA1	P38398-1.2	A1082T	Pathogenic	0.571
BRCA1	P38398-1.2	A1082V	Pathogenic	0.631
BRCA1	P38398-1.2	A1082W	Pathogenic	0.948
BRCA1	P38398-1.2	A1082Y	Pathogenic	0.888
BRCA1	P38398-1.2	M1083A	Neutral	0.128
BRCA1	P38398-1.2	M1083C	Neutral	0.089
BRCA1	P38398-1.2	M1083D	Neutral	0.149
BRCA1	P38398-1.2	M1083E	Neutral	0.076
BRCA1	P38398-1.2	M1083F	Neutral	0.036
BRCA1	P38398-1.2	M1083G	Neutral	0.316
BRCA1	P38398-1.2	M1083H	Neutral	0.064
BRCA1	P38398-1.2	M1083I	Neutral	0.02
BRCA1	P38398-1.2	M1083K	Neutral	0.049
BRCA1	P38398-1.2	M1083L	Neutral	0.014
BRCA1	P38398-1.2	M1083N	Neutral	0.099
BRCA1	P38398-1.2	M1083P	Neutral	0.114
BRCA1	P38398-1.2	M1083Q	Neutral	0.034
BRCA1	P38398-1.2	M1083R	Neutral	0.065
BRCA1	P38398-1.2	M1083S	Neutral	0.114
BRCA1	P38398-1.2	M1083T	Neutral	0.076
BRCA1	P38398-1.2	M1083V	Neutral	0.03
BRCA1	P38398-1.2	M1083W	Neutral	0.09
BRCA1	P38398-1.2	M1083Y	Neutral	0.058
BRCA1	P38398-1.2	L1084A	Pathogenic	0.954
BRCA1	P38398-1.2	L1084C	Pathogenic	0.933
BRCA1	P38398-1.2	L1084D	Pathogenic	0.973
BRCA1	P38398-1.2	L1084E	Pathogenic	0.943
BRCA1	P38398-1.2	L1084F	Pathogenic	0.843
BRCA1	P38398-1.2	L1084G	Pathogenic	0.99
BRCA1	P38398-1.2	L1084H	Pathogenic	0.933
BRCA1	P38398-1.2	L1084I	Pathogenic	0.669
BRCA1	P38398-1.2	L1084K	Pathogenic	0.913
BRCA1	P38398-1.2	L1084M	Pathogenic	0.668
BRCA1	P38398-1.2	L1084N	Pathogenic	0.957
BRCA1	P38398-1.2	L1084P	Pathogenic	0.963
BRCA1	P38398-1.2	L1084Q	Pathogenic	0.913
BRCA1	P38398-1.2	L1084R	Pathogenic	0.934
BRCA1	P38398-1.2	L1084S	Pathogenic	0.963
BRCA1	P38398-1.2	L1084T	Pathogenic	0.921
BRCA1	P38398-1.2	L1084V	Pathogenic	0.815
BRCA1	P38398-1.2	L1084W	Pathogenic	0.953
BRCA1	P38398-1.2	L1084Y	Pathogenic	0.897
BRCA1	P38398-1.2	R1085A	Pathogenic	0.793
BRCA1	P38398-1.2	R1085C	Pathogenic	0.837
BRCA1	P38398-1.2	R1085D	Pathogenic	0.768
BRCA1	P38398-1.2	R1085E	Pathogenic	0.517
BRCA1	P38398-1.2	R1085F	Pathogenic	0.63
BRCA1	P38398-1.2	R1085G	Pathogenic	0.894
BRCA1	P38398-1.2	R1085H	Neutral	0.463
BRCA1	P38398-1.2	R1085I	Pathogenic	0.685
BRCA1	P38398-1.2	R1085K	Neutral	0.226
BRCA1	P38398-1.2	R1085L	Pathogenic	0.603
BRCA1	P38398-1.2	R1085M	Pathogenic	0.515
BRCA1	P38398-1.2	R1085N	Pathogenic	0.588
BRCA1	P38398-1.2	R1085P	Pathogenic	0.767
BRCA1	P38398-1.2	R1085Q	Neutral	0.397
BRCA1	P38398-1.2	R1085S	Pathogenic	0.772
BRCA1	P38398-1.2	R1085T	Pathogenic	0.683
BRCA1	P38398-1.2	R1085V	Pathogenic	0.771
BRCA1	P38398-1.2	R1085W	Pathogenic	0.639
BRCA1	P38398-1.2	R1085Y	Pathogenic	0.513
BRCA1	P38398-1.2	L1086A	Pathogenic	0.844
BRCA1	P38398-1.2	L1086C	Pathogenic	0.782
BRCA1	P38398-1.2	L1086D	Pathogenic	0.903
BRCA1	P38398-1.2	L1086E	Pathogenic	0.812
BRCA1	P38398-1.2	L1086F	Pathogenic	0.581
BRCA1	P38398-1.2	L1086G	Pathogenic	0.961
BRCA1	P38398-1.2	L1086H	Pathogenic	0.782
BRCA1	P38398-1.2	L1086I	Neutral	0.344
BRCA1	P38398-1.2	L1086K	Pathogenic	0.732
BRCA1	P38398-1.2	L1086M	Neutral	0.342
BRCA1	P38398-1.2	L1086N	Pathogenic	0.853
BRCA1	P38398-1.2	L1086P	Pathogenic	0.871
BRCA1	P38398-1.2	L1086Q	Pathogenic	0.731
BRCA1	P38398-1.2	L1086R	Pathogenic	0.785
BRCA1	P38398-1.2	L1086S	Pathogenic	0.871
BRCA1	P38398-1.2	L1086T	Pathogenic	0.752
BRCA1	P38398-1.2	L1086V	Pathogenic	0.533
BRCA1	P38398-1.2	L1086W	Pathogenic	0.841
BRCA1	P38398-1.2	L1086Y	Pathogenic	0.693
BRCA1	P38398-1.2	G1087A	Pathogenic	0.629
BRCA1	P38398-1.2	G1087C	Pathogenic	0.884
BRCA1	P38398-1.2	G1087D	Pathogenic	0.805
BRCA1	P38398-1.2	G1087E	Pathogenic	0.899
BRCA1	P38398-1.2	G1087F	Pathogenic	0.957
BRCA1	P38398-1.2	G1087H	Pathogenic	0.916
BRCA1	P38398-1.2	G1087I	Pathogenic	0.962
BRCA1	P38398-1.2	G1087K	Pathogenic	0.94
BRCA1	P38398-1.2	G1087L	Pathogenic	0.962
BRCA1	P38398-1.2	G1087M	Pathogenic	0.946
BRCA1	P38398-1.2	G1087N	Pathogenic	0.762
BRCA1	P38398-1.2	G1087P	Pathogenic	0.853
BRCA1	P38398-1.2	G1087Q	Pathogenic	0.909
BRCA1	P38398-1.2	G1087R	Pathogenic	0.954
BRCA1	P38398-1.2	G1087S	Pathogenic	0.66
BRCA1	P38398-1.2	G1087T	Pathogenic	0.862
BRCA1	P38398-1.2	G1087V	Pathogenic	0.92
BRCA1	P38398-1.2	G1087W	Pathogenic	0.966
BRCA1	P38398-1.2	G1087Y	Pathogenic	0.963
BRCA1	P38398-1.2	V1088A	Pathogenic	0.546
BRCA1	P38398-1.2	V1088C	Pathogenic	0.535
BRCA1	P38398-1.2	V1088D	Pathogenic	0.673
BRCA1	P38398-1.2	V1088E	Pathogenic	0.535
BRCA1	P38398-1.2	V1088F	Pathogenic	0.593
BRCA1	P38398-1.2	V1088G	Pathogenic	0.845
BRCA1	P38398-1.2	V1088H	Pathogenic	0.672
BRCA1	P38398-1.2	V1088I	Neutral	0.21
BRCA1	P38398-1.2	V1088K	Pathogenic	0.671
BRCA1	P38398-1.2	V1088L	Neutral	0.356
BRCA1	P38398-1.2	V1088M	Neutral	0.358
BRCA1	P38398-1.2	V1088N	Pathogenic	0.649
BRCA1	P38398-1.2	V1088P	Pathogenic	0.601
BRCA1	P38398-1.2	V1088Q	Pathogenic	0.564
BRCA1	P38398-1.2	V1088R	Pathogenic	0.796
BRCA1	P38398-1.2	V1088S	Pathogenic	0.684
BRCA1	P38398-1.2	V1088T	Neutral	0.403
BRCA1	P38398-1.2	V1088W	Pathogenic	0.848
BRCA1	P38398-1.2	V1088Y	Pathogenic	0.627
BRCA1	P38398-1.2	L1089A	Neutral	0.21
BRCA1	P38398-1.2	L1089C	Neutral	0.15
BRCA1	P38398-1.2	L1089D	Neutral	0.313
BRCA1	P38398-1.2	L1089E	Neutral	0.176
BRCA1	P38398-1.2	L1089F	Neutral	0.064
BRCA1	P38398-1.2	L1089G	Pathogenic	0.546
BRCA1	P38398-1.2	L1089H	Neutral	0.15
BRCA1	P38398-1.2	L1089I	Neutral	0.025
BRCA1	P38398-1.2	L1089K	Neutral	0.119
BRCA1	P38398-1.2	L1089M	Neutral	0.025
BRCA1	P38398-1.2	L1089N	Neutral	0.222
BRCA1	P38398-1.2	L1089P	Neutral	0.25
BRCA1	P38398-1.2	L1089Q	Neutral	0.118
BRCA1	P38398-1.2	L1089R	Neutral	0.152
BRCA1	P38398-1.2	L1089S	Neutral	0.25
BRCA1	P38398-1.2	L1089T	Neutral	0.13
BRCA1	P38398-1.2	L1089V	Neutral	0.053
BRCA1	P38398-1.2	L1089W	Neutral	0.207
BRCA1	P38398-1.2	L1089Y	Neutral	0.1
BRCA1	P38398-1.2	Q1090A	Pathogenic	0.99
BRCA1	P38398-1.2	Q1090C	Pathogenic	0.993
BRCA1	P38398-1.2	Q1090D	Pathogenic	0.976
BRCA1	P38398-1.2	Q1090E	Pathogenic	0.929
BRCA1	P38398-1.2	Q1090F	Pathogenic	0.991
BRCA1	P38398-1.2	Q1090G	Pathogenic	0.995
BRCA1	P38398-1.2	Q1090H	Pathogenic	0.964
BRCA1	P38398-1.2	Q1090I	Pathogenic	0.989
BRCA1	P38398-1.2	Q1090K	Pathogenic	0.964
BRCA1	P38398-1.2	Q1090L	Pathogenic	0.984
BRCA1	P38398-1.2	Q1090M	Pathogenic	0.967
BRCA1	P38398-1.2	Q1090N	Pathogenic	0.973
BRCA1	P38398-1.2	Q1090P	Pathogenic	0.983
BRCA1	P38398-1.2	Q1090R	Pathogenic	0.973
BRCA1	P38398-1.2	Q1090S	Pathogenic	0.984
BRCA1	P38398-1.2	Q1090T	Pathogenic	0.982
BRCA1	P38398-1.2	Q1090V	Pathogenic	0.984
BRCA1	P38398-1.2	Q1090W	Pathogenic	0.993
BRCA1	P38398-1.2	Q1090Y	Pathogenic	0.984
BRCA1	P38398-1.2	P1091A	Pathogenic	0.979
BRCA1	P38398-1.2	P1091C	Pathogenic	0.985
BRCA1	P38398-1.2	P1091D	Pathogenic	0.966
BRCA1	P38398-1.2	P1091E	Pathogenic	0.977
BRCA1	P38398-1.2	P1091F	Pathogenic	0.996
BRCA1	P38398-1.2	P1091G	Pathogenic	0.99
BRCA1	P38398-1.2	P1091H	Pathogenic	0.987
BRCA1	P38398-1.2	P1091I	Pathogenic	0.992
BRCA1	P38398-1.2	P1091K	Pathogenic	0.987
BRCA1	P38398-1.2	P1091L	Pathogenic	0.992
BRCA1	P38398-1.2	P1091M	Pathogenic	0.988
BRCA1	P38398-1.2	P1091N	Pathogenic	0.978
BRCA1	P38398-1.2	P1091Q	Pathogenic	0.979
BRCA1	P38398-1.2	P1091R	Pathogenic	0.993
BRCA1	P38398-1.2	P1091S	Pathogenic	0.976
BRCA1	P38398-1.2	P1091T	Pathogenic	0.968
BRCA1	P38398-1.2	P1091V	Pathogenic	0.983
BRCA1	P38398-1.2	P1091W	Pathogenic	0.998
BRCA1	P38398-1.2	P1091Y	Pathogenic	0.994
BRCA1	P38398-1.2	E1092A	Pathogenic	0.657
BRCA1	P38398-1.2	E1092C	Pathogenic	0.787
BRCA1	P38398-1.2	E1092D	Neutral	0.277
BRCA1	P38398-1.2	E1092F	Pathogenic	0.73
BRCA1	P38398-1.2	E1092G	Pathogenic	0.809
BRCA1	P38398-1.2	E1092H	Neutral	0.391
BRCA1	P38398-1.2	E1092I	Pathogenic	0.679
BRCA1	P38398-1.2	E1092K	Neutral	0.396
BRCA1	P38398-1.2	E1092L	Pathogenic	0.679
BRCA1	P38398-1.2	E1092M	Pathogenic	0.597
BRCA1	P38398-1.2	E1092N	Neutral	0.415
BRCA1	P38398-1.2	E1092P	Pathogenic	0.532
BRCA1	P38398-1.2	E1092Q	Neutral	0.222
BRCA1	P38398-1.2	E1092R	Pathogenic	0.557
BRCA1	P38398-1.2	E1092S	Pathogenic	0.539
BRCA1	P38398-1.2	E1092T	Pathogenic	0.518
BRCA1	P38398-1.2	E1092V	Pathogenic	0.538
BRCA1	P38398-1.2	E1092W	Pathogenic	0.833
BRCA1	P38398-1.2	E1092Y	Pathogenic	0.685
BRCA1	P38398-1.2	V1093A	Neutral	0.471
BRCA1	P38398-1.2	V1093C	Neutral	0.46
BRCA1	P38398-1.2	V1093D	Pathogenic	0.604
BRCA1	P38398-1.2	V1093E	Neutral	0.46
BRCA1	P38398-1.2	V1093F	Pathogenic	0.52
BRCA1	P38398-1.2	V1093G	Pathogenic	0.801
BRCA1	P38398-1.2	V1093H	Pathogenic	0.603
BRCA1	P38398-1.2	V1093I	Neutral	0.165
BRCA1	P38398-1.2	V1093K	Pathogenic	0.601
BRCA1	P38398-1.2	V1093L	Neutral	0.291
BRCA1	P38398-1.2	V1093M	Neutral	0.293
BRCA1	P38398-1.2	V1093N	Pathogenic	0.578
BRCA1	P38398-1.2	V1093P	Pathogenic	0.528
BRCA1	P38398-1.2	V1093Q	Neutral	0.49
BRCA1	P38398-1.2	V1093R	Pathogenic	0.743
BRCA1	P38398-1.2	V1093S	Pathogenic	0.616
BRCA1	P38398-1.2	V1093T	Neutral	0.333
BRCA1	P38398-1.2	V1093W	Pathogenic	0.805
BRCA1	P38398-1.2	V1093Y	Pathogenic	0.554
BRCA1	P38398-1.2	Y1094A	Pathogenic	0.545
BRCA1	P38398-1.2	Y1094C	Neutral	0.443
BRCA1	P38398-1.2	Y1094D	Neutral	0.498
BRCA1	P38398-1.2	Y1094E	Neutral	0.316
BRCA1	P38398-1.2	Y1094F	Neutral	0.041
BRCA1	P38398-1.2	Y1094G	Pathogenic	0.723
BRCA1	P38398-1.2	Y1094H	Neutral	0.082
BRCA1	P38398-1.2	Y1094I	Neutral	0.189
BRCA1	P38398-1.2	Y1094K	Neutral	0.205
BRCA1	P38398-1.2	Y1094L	Neutral	0.19
BRCA1	P38398-1.2	Y1094M	Neutral	0.191
BRCA1	P38398-1.2	Y1094N	Neutral	0.382
BRCA1	P38398-1.2	Y1094P	Pathogenic	0.51
BRCA1	P38398-1.2	Y1094Q	Neutral	0.225
BRCA1	P38398-1.2	Y1094R	Neutral	0.209
BRCA1	P38398-1.2	Y1094S	Pathogenic	0.51
BRCA1	P38398-1.2	Y1094T	Neutral	0.402
BRCA1	P38398-1.2	Y1094V	Neutral	0.265
BRCA1	P38398-1.2	Y1094W	Neutral	0.08
BRCA1	P38398-1.2	K1095A	Neutral	0.328
BRCA1	P38398-1.2	K1095C	Neutral	0.395
BRCA1	P38398-1.2	K1095D	Neutral	0.226
BRCA1	P38398-1.2	K1095E	Neutral	0.086
BRCA1	P38398-1.2	K1095F	Neutral	0.178
BRCA1	P38398-1.2	K1095G	Pathogenic	0.519
BRCA1	P38398-1.2	K1095H	Neutral	0.136
BRCA1	P38398-1.2	K1095I	Neutral	0.217
BRCA1	P38398-1.2	K1095L	Neutral	0.162
BRCA1	P38398-1.2	K1095M	Neutral	0.119
BRCA1	P38398-1.2	K1095N	Neutral	0.153
BRCA1	P38398-1.2	K1095P	Neutral	0.225
BRCA1	P38398-1.2	K1095Q	Neutral	0.077
BRCA1	P38398-1.2	K1095R	Neutral	0.047
BRCA1	P38398-1.2	K1095S	Neutral	0.23
BRCA1	P38398-1.2	K1095T	Neutral	0.215
BRCA1	P38398-1.2	K1095V	Neutral	0.229
BRCA1	P38398-1.2	K1095W	Neutral	0.286
BRCA1	P38398-1.2	K1095Y	Neutral	0.149
BRCA1	P38398-1.2	Q1096A	Pathogenic	0.889
BRCA1	P38398-1.2	Q1096C	Pathogenic	0.915
BRCA1	P38398-1.2	Q1096D	Pathogenic	0.766
BRCA1	P38398-1.2	Q1096E	Pathogenic	0.515
BRCA1	P38398-1.2	Q1096F	Pathogenic	0.901
BRCA1	P38398-1.2	Q1096G	Pathogenic	0.947
BRCA1	P38398-1.2	Q1096H	Pathogenic	0.683
BRCA1	P38398-1.2	Q1096I	Pathogenic	0.877
BRCA1	P38398-1.2	Q1096K	Pathogenic	0.684
BRCA1	P38398-1.2	Q1096L	Pathogenic	0.832
BRCA1	P38398-1.2	Q1096M	Pathogenic	0.707
BRCA1	P38398-1.2	Q1096N	Pathogenic	0.746
BRCA1	P38398-1.2	Q1096P	Pathogenic	0.827
BRCA1	P38398-1.2	Q1096R	Pathogenic	0.743
BRCA1	P38398-1.2	Q1096S	Pathogenic	0.831
BRCA1	P38398-1.2	Q1096T	Pathogenic	0.819
BRCA1	P38398-1.2	Q1096V	Pathogenic	0.83
BRCA1	P38398-1.2	Q1096W	Pathogenic	0.921
BRCA1	P38398-1.2	Q1096Y	Pathogenic	0.836
BRCA1	P38398-1.2	S1097A	Neutral	0.188
BRCA1	P38398-1.2	S1097C	Neutral	0.357
BRCA1	P38398-1.2	S1097D	Neutral	0.302
BRCA1	P38398-1.2	S1097E	Neutral	0.393
BRCA1	P38398-1.2	S1097F	Pathogenic	0.7
BRCA1	P38398-1.2	S1097G	Neutral	0.339
BRCA1	P38398-1.2	S1097H	Pathogenic	0.534
BRCA1	P38398-1.2	S1097I	Pathogenic	0.646
BRCA1	P38398-1.2	S1097K	Pathogenic	0.534
BRCA1	P38398-1.2	S1097L	Pathogenic	0.647
BRCA1	P38398-1.2	S1097M	Pathogenic	0.562
BRCA1	P38398-1.2	S1097N	Neutral	0.252
BRCA1	P38398-1.2	S1097P	Neutral	0.378
BRCA1	P38398-1.2	S1097Q	Neutral	0.422
BRCA1	P38398-1.2	S1097R	Pathogenic	0.687
BRCA1	P38398-1.2	S1097T	Neutral	0.241
BRCA1	P38398-1.2	S1097V	Pathogenic	0.548
BRCA1	P38398-1.2	S1097W	Pathogenic	0.861
BRCA1	P38398-1.2	S1097Y	Pathogenic	0.73
BRCA1	P38398-1.2	L1098A	Pathogenic	0.788
BRCA1	P38398-1.2	L1098C	Pathogenic	0.711
BRCA1	P38398-1.2	L1098D	Pathogenic	0.864
BRCA1	P38398-1.2	L1098E	Pathogenic	0.748
BRCA1	P38398-1.2	L1098F	Neutral	0.487
BRCA1	P38398-1.2	L1098G	Pathogenic	0.944
BRCA1	P38398-1.2	L1098H	Pathogenic	0.711
BRCA1	P38398-1.2	L1098I	Neutral	0.264
BRCA1	P38398-1.2	L1098K	Pathogenic	0.652
BRCA1	P38398-1.2	L1098M	Neutral	0.263
BRCA1	P38398-1.2	L1098N	Pathogenic	0.798
BRCA1	P38398-1.2	L1098P	Pathogenic	0.823
BRCA1	P38398-1.2	L1098Q	Pathogenic	0.65
BRCA1	P38398-1.2	L1098R	Pathogenic	0.714
BRCA1	P38398-1.2	L1098S	Pathogenic	0.823
BRCA1	P38398-1.2	L1098T	Pathogenic	0.675
BRCA1	P38398-1.2	L1098V	Neutral	0.439
BRCA1	P38398-1.2	L1098W	Pathogenic	0.784
BRCA1	P38398-1.2	L1098Y	Pathogenic	0.607
BRCA1	P38398-1.2	P1099A	Pathogenic	0.897
BRCA1	P38398-1.2	P1099C	Pathogenic	0.923
BRCA1	P38398-1.2	P1099D	Pathogenic	0.84
BRCA1	P38398-1.2	P1099E	Pathogenic	0.887
BRCA1	P38398-1.2	P1099F	Pathogenic	0.977
BRCA1	P38398-1.2	P1099G	Pathogenic	0.95
BRCA1	P38398-1.2	P1099H	Pathogenic	0.933
BRCA1	P38398-1.2	P1099I	Pathogenic	0.958
BRCA1	P38398-1.2	P1099K	Pathogenic	0.933
BRCA1	P38398-1.2	P1099L	Pathogenic	0.958
BRCA1	P38398-1.2	P1099M	Pathogenic	0.941
BRCA1	P38398-1.2	P1099N	Pathogenic	0.894
BRCA1	P38398-1.2	P1099Q	Pathogenic	0.898
BRCA1	P38398-1.2	P1099R	Pathogenic	0.964
BRCA1	P38398-1.2	P1099S	Pathogenic	0.884
BRCA1	P38398-1.2	P1099T	Pathogenic	0.849
BRCA1	P38398-1.2	P1099V	Pathogenic	0.913
BRCA1	P38398-1.2	P1099W	Pathogenic	0.987
BRCA1	P38398-1.2	P1099Y	Pathogenic	0.971
BRCA1	P38398-1.2	G1100A	Neutral	0.001
BRCA1	P38398-1.2	G1100C	Neutral	0.004
BRCA1	P38398-1.2	G1100D	Neutral	0.002
BRCA1	P38398-1.2	G1100E	Neutral	0.005
BRCA1	P38398-1.2	G1100F	Neutral	0.012
BRCA1	P38398-1.2	G1100H	Neutral	0.006
BRCA1	P38398-1.2	G1100I	Neutral	0.013
BRCA1	P38398-1.2	G1100K	Neutral	0.008
BRCA1	P38398-1.2	G1100L	Neutral	0.013
BRCA1	P38398-1.2	G1100M	Neutral	0.009
BRCA1	P38398-1.2	G1100N	Neutral	0.002
BRCA1	P38398-1.2	G1100P	Neutral	0.003
BRCA1	P38398-1.2	G1100Q	Neutral	0.005
BRCA1	P38398-1.2	G1100R	Neutral	0.011
BRCA1	P38398-1.2	G1100S	Neutral	0.001
BRCA1	P38398-1.2	G1100T	Neutral	0.003
BRCA1	P38398-1.2	G1100V	Neutral	0.006
BRCA1	P38398-1.2	G1100W	Neutral	0.015
BRCA1	P38398-1.2	G1100Y	Neutral	0.014
BRCA1	P38398-1.2	S1101A	Neutral	0.022
BRCA1	P38398-1.2	S1101C	Neutral	0.052
BRCA1	P38398-1.2	S1101D	Neutral	0.041
BRCA1	P38398-1.2	S1101E	Neutral	0.06
BRCA1	P38398-1.2	S1101F	Neutral	0.187
BRCA1	P38398-1.2	S1101G	Neutral	0.048
BRCA1	P38398-1.2	S1101H	Neutral	0.102
BRCA1	P38398-1.2	S1101I	Neutral	0.153
BRCA1	P38398-1.2	S1101K	Neutral	0.102
BRCA1	P38398-1.2	S1101L	Neutral	0.153
BRCA1	P38398-1.2	S1101M	Neutral	0.112
BRCA1	P38398-1.2	S1101N	Neutral	0.032
BRCA1	P38398-1.2	S1101P	Neutral	0.057
BRCA1	P38398-1.2	S1101Q	Neutral	0.067
BRCA1	P38398-1.2	S1101R	Neutral	0.178
BRCA1	P38398-1.2	S1101T	Neutral	0.03
BRCA1	P38398-1.2	S1101V	Neutral	0.107
BRCA1	P38398-1.2	S1101W	Neutral	0.38
BRCA1	P38398-1.2	S1101Y	Neutral	0.211
BRCA1	P38398-1.2	N1102A	Neutral	0.355
BRCA1	P38398-1.2	N1102C	Neutral	0.339
BRCA1	P38398-1.2	N1102D	Neutral	0.099
BRCA1	P38398-1.2	N1102E	Neutral	0.16
BRCA1	P38398-1.2	N1102F	Neutral	0.491
BRCA1	P38398-1.2	N1102G	Neutral	0.29
BRCA1	P38398-1.2	N1102H	Neutral	0.137
BRCA1	P38398-1.2	N1102I	Neutral	0.43
BRCA1	P38398-1.2	N1102K	Neutral	0.251
BRCA1	P38398-1.2	N1102L	Neutral	0.43
BRCA1	P38398-1.2	N1102M	Neutral	0.346
BRCA1	P38398-1.2	N1102P	Neutral	0.247
BRCA1	P38398-1.2	N1102Q	Neutral	0.174
BRCA1	P38398-1.2	N1102R	Neutral	0.309
BRCA1	P38398-1.2	N1102S	Neutral	0.14
BRCA1	P38398-1.2	N1102T	Neutral	0.13
BRCA1	P38398-1.2	N1102V	Neutral	0.333
BRCA1	P38398-1.2	N1102W	Pathogenic	0.719
BRCA1	P38398-1.2	N1102Y	Neutral	0.437
BRCA1	P38398-1.2	C1103A	Neutral	0.192
BRCA1	P38398-1.2	C1103D	Neutral	0.337
BRCA1	P38398-1.2	C1103E	Pathogenic	0.523
BRCA1	P38398-1.2	C1103F	Neutral	0.489
BRCA1	P38398-1.2	C1103G	Pathogenic	0.518
BRCA1	P38398-1.2	C1103H	Neutral	0.485
BRCA1	P38398-1.2	C1103I	Neutral	0.342
BRCA1	P38398-1.2	C1103K	Pathogenic	0.574
BRCA1	P38398-1.2	C1103L	Neutral	0.343
BRCA1	P38398-1.2	C1103M	Neutral	0.345
BRCA1	P38398-1.2	C1103N	Neutral	0.363
BRCA1	P38398-1.2	C1103P	Neutral	0.339
BRCA1	P38398-1.2	C1103Q	Neutral	0.461
BRCA1	P38398-1.2	C1103R	Pathogenic	0.642
BRCA1	P38398-1.2	C1103S	Neutral	0.229
BRCA1	P38398-1.2	C1103T	Neutral	0.208
BRCA1	P38398-1.2	C1103V	Neutral	0.257
BRCA1	P38398-1.2	C1103W	Pathogenic	0.638
BRCA1	P38398-1.2	C1103Y	Pathogenic	0.526
BRCA1	P38398-1.2	K1104A	Neutral	0.228
BRCA1	P38398-1.2	K1104C	Neutral	0.283
BRCA1	P38398-1.2	K1104D	Neutral	0.15
BRCA1	P38398-1.2	K1104E	Neutral	0.054
BRCA1	P38398-1.2	K1104F	Neutral	0.116
BRCA1	P38398-1.2	K1104G	Neutral	0.394
BRCA1	P38398-1.2	K1104H	Neutral	0.087
BRCA1	P38398-1.2	K1104I	Neutral	0.143
BRCA1	P38398-1.2	K1104L	Neutral	0.104
BRCA1	P38398-1.2	K1104M	Neutral	0.075
BRCA1	P38398-1.2	K1104N	Neutral	0.099
BRCA1	P38398-1.2	K1104P	Neutral	0.149
BRCA1	P38398-1.2	K1104Q	Neutral	0.048
BRCA1	P38398-1.2	K1104R	Neutral	0.029
BRCA1	P38398-1.2	K1104S	Neutral	0.153
BRCA1	P38398-1.2	K1104T	Neutral	0.142
BRCA1	P38398-1.2	K1104V	Neutral	0.152
BRCA1	P38398-1.2	K1104W	Neutral	0.195
BRCA1	P38398-1.2	K1104Y	Neutral	0.096
BRCA1	P38398-1.2	H1105A	Neutral	0.01
BRCA1	P38398-1.2	H1105C	Neutral	0.009
BRCA1	P38398-1.2	H1105D	Neutral	0.004
BRCA1	P38398-1.2	H1105E	Neutral	0.002
BRCA1	P38398-1.2	H1105F	Neutral	0.003
BRCA1	P38398-1.2	H1105G	Neutral	0.015
BRCA1	P38398-1.2	H1105I	Neutral	0.005
BRCA1	P38398-1.2	H1105K	Neutral	0.003
BRCA1	P38398-1.2	H1105L	Neutral	0.005
BRCA1	P38398-1.2	H1105M	Neutral	0.003
BRCA1	P38398-1.2	H1105N	Neutral	0.002
BRCA1	P38398-1.2	H1105P	Neutral	0.006
BRCA1	P38398-1.2	H1105Q	Neutral	0.002
BRCA1	P38398-1.2	H1105R	Neutral	0.003
BRCA1	P38398-1.2	H1105S	Neutral	0.006
BRCA1	P38398-1.2	H1105T	Neutral	0.005
BRCA1	P38398-1.2	H1105V	Neutral	0.006
BRCA1	P38398-1.2	H1105W	Neutral	0.008
BRCA1	P38398-1.2	H1105Y	Neutral	0.001
BRCA1	P38398-1.2	P1106A	Pathogenic	0.763
BRCA1	P38398-1.2	P1106C	Pathogenic	0.814
BRCA1	P38398-1.2	P1106D	Pathogenic	0.659
BRCA1	P38398-1.2	P1106E	Pathogenic	0.743
BRCA1	P38398-1.2	P1106F	Pathogenic	0.939
BRCA1	P38398-1.2	P1106G	Pathogenic	0.875
BRCA1	P38398-1.2	P1106H	Pathogenic	0.838
BRCA1	P38398-1.2	P1106I	Pathogenic	0.894
BRCA1	P38398-1.2	P1106K	Pathogenic	0.836
BRCA1	P38398-1.2	P1106L	Pathogenic	0.894
BRCA1	P38398-1.2	P1106M	Pathogenic	0.855
BRCA1	P38398-1.2	P1106N	Pathogenic	0.757
BRCA1	P38398-1.2	P1106Q	Pathogenic	0.765
BRCA1	P38398-1.2	P1106R	Pathogenic	0.908
BRCA1	P38398-1.2	P1106S	Pathogenic	0.737
BRCA1	P38398-1.2	P1106T	Pathogenic	0.673
BRCA1	P38398-1.2	P1106V	Pathogenic	0.795
BRCA1	P38398-1.2	P1106W	Pathogenic	0.966
BRCA1	P38398-1.2	P1106Y	Pathogenic	0.926
BRCA1	P38398-1.2	E1107A	Pathogenic	0.742
BRCA1	P38398-1.2	E1107C	Pathogenic	0.847
BRCA1	P38398-1.2	E1107D	Neutral	0.365
BRCA1	P38398-1.2	E1107F	Pathogenic	0.802
BRCA1	P38398-1.2	E1107G	Pathogenic	0.864
BRCA1	P38398-1.2	E1107H	Neutral	0.491
BRCA1	P38398-1.2	E1107I	Pathogenic	0.761
BRCA1	P38398-1.2	E1107K	Neutral	0.496
BRCA1	P38398-1.2	E1107L	Pathogenic	0.761
BRCA1	P38398-1.2	E1107M	Pathogenic	0.691
BRCA1	P38398-1.2	E1107N	Pathogenic	0.516
BRCA1	P38398-1.2	E1107P	Pathogenic	0.631
BRCA1	P38398-1.2	E1107Q	Neutral	0.3
BRCA1	P38398-1.2	E1107R	Pathogenic	0.654
BRCA1	P38398-1.2	E1107S	Pathogenic	0.638
BRCA1	P38398-1.2	E1107T	Pathogenic	0.618
BRCA1	P38398-1.2	E1107V	Pathogenic	0.636
BRCA1	P38398-1.2	E1107W	Pathogenic	0.882
BRCA1	P38398-1.2	E1107Y	Pathogenic	0.766
BRCA1	P38398-1.2	I1108A	Neutral	0.148
BRCA1	P38398-1.2	I1108C	Neutral	0.103
BRCA1	P38398-1.2	I1108D	Neutral	0.171
BRCA1	P38398-1.2	I1108E	Neutral	0.122
BRCA1	P38398-1.2	I1108F	Neutral	0.043
BRCA1	P38398-1.2	I1108G	Neutral	0.44
BRCA1	P38398-1.2	I1108H	Neutral	0.104
BRCA1	P38398-1.2	I1108K	Neutral	0.112
BRCA1	P38398-1.2	I1108L	Neutral	0.017
BRCA1	P38398-1.2	I1108M	Neutral	0.023
BRCA1	P38398-1.2	I1108N	Neutral	0.157
BRCA1	P38398-1.2	I1108P	Neutral	0.179
BRCA1	P38398-1.2	I1108Q	Neutral	0.111
BRCA1	P38398-1.2	I1108R	Neutral	0.144
BRCA1	P38398-1.2	I1108S	Neutral	0.178
BRCA1	P38398-1.2	I1108T	Neutral	0.089
BRCA1	P38398-1.2	I1108V	Neutral	0.017
BRCA1	P38398-1.2	I1108W	Neutral	0.197
BRCA1	P38398-1.2	I1108Y	Neutral	0.067
BRCA1	P38398-1.2	K1109A	Pathogenic	0.52
BRCA1	P38398-1.2	K1109C	Pathogenic	0.592
BRCA1	P38398-1.2	K1109D	Neutral	0.394
BRCA1	P38398-1.2	K1109E	Neutral	0.173
BRCA1	P38398-1.2	K1109F	Neutral	0.325
BRCA1	P38398-1.2	K1109G	Pathogenic	0.705
BRCA1	P38398-1.2	K1109H	Neutral	0.259
BRCA1	P38398-1.2	K1109I	Neutral	0.381
BRCA1	P38398-1.2	K1109L	Neutral	0.3
BRCA1	P38398-1.2	K1109M	Neutral	0.231
BRCA1	P38398-1.2	K1109N	Neutral	0.287
BRCA1	P38398-1.2	K1109P	Neutral	0.392
BRCA1	P38398-1.2	K1109Q	Neutral	0.157
BRCA1	P38398-1.2	K1109R	Neutral	0.099
BRCA1	P38398-1.2	K1109S	Neutral	0.399
BRCA1	P38398-1.2	K1109T	Neutral	0.378
BRCA1	P38398-1.2	K1109V	Neutral	0.397
BRCA1	P38398-1.2	K1109W	Neutral	0.471
BRCA1	P38398-1.2	K1109Y	Neutral	0.28
BRCA1	P38398-1.2	K1110A	Neutral	0.03
BRCA1	P38398-1.2	K1110C	Neutral	0.04
BRCA1	P38398-1.2	K1110D	Neutral	0.018
BRCA1	P38398-1.2	K1110E	Neutral	0.006
BRCA1	P38398-1.2	K1110F	Neutral	0.014
BRCA1	P38398-1.2	K1110G	Neutral	0.064
BRCA1	P38398-1.2	K1110H	Neutral	0.01
BRCA1	P38398-1.2	K1110I	Neutral	0.017
BRCA1	P38398-1.2	K1110L	Neutral	0.012
BRCA1	P38398-1.2	K1110M	Neutral	0.008
BRCA1	P38398-1.2	K1110N	Neutral	0.011
BRCA1	P38398-1.2	K1110P	Neutral	0.018
BRCA1	P38398-1.2	K1110Q	Neutral	0.005
BRCA1	P38398-1.2	K1110R	Neutral	0.003
BRCA1	P38398-1.2	K1110S	Neutral	0.019
BRCA1	P38398-1.2	K1110T	Neutral	0.017
BRCA1	P38398-1.2	K1110V	Neutral	0.018
BRCA1	P38398-1.2	K1110W	Neutral	0.025
BRCA1	P38398-1.2	K1110Y	Neutral	0.011
BRCA1	P38398-1.2	Q1111A	Neutral	0.457
BRCA1	P38398-1.2	Q1111C	Pathogenic	0.53
BRCA1	P38398-1.2	Q1111D	Neutral	0.255
BRCA1	P38398-1.2	Q1111E	Neutral	0.1
BRCA1	P38398-1.2	Q1111F	Neutral	0.488
BRCA1	P38398-1.2	Q1111G	Pathogenic	0.65
BRCA1	P38398-1.2	Q1111H	Neutral	0.184
BRCA1	P38398-1.2	Q1111I	Neutral	0.427
BRCA1	P38398-1.2	Q1111K	Neutral	0.185
BRCA1	P38398-1.2	Q1111L	Neutral	0.342
BRCA1	P38398-1.2	Q1111M	Neutral	0.202
BRCA1	P38398-1.2	Q1111N	Neutral	0.236
BRCA1	P38398-1.2	Q1111P	Neutral	0.334
BRCA1	P38398-1.2	Q1111R	Neutral	0.233
BRCA1	P38398-1.2	Q1111S	Neutral	0.34
BRCA1	P38398-1.2	Q1111T	Neutral	0.321
BRCA1	P38398-1.2	Q1111V	Neutral	0.339
BRCA1	P38398-1.2	Q1111W	Pathogenic	0.55
BRCA1	P38398-1.2	Q1111Y	Neutral	0.348
BRCA1	P38398-1.2	E1112A	Neutral	0.095
BRCA1	P38398-1.2	E1112C	Neutral	0.168
BRCA1	P38398-1.2	E1112D	Neutral	0.021
BRCA1	P38398-1.2	E1112F	Neutral	0.129
BRCA1	P38398-1.2	E1112G	Neutral	0.188
BRCA1	P38398-1.2	E1112H	Neutral	0.034
BRCA1	P38398-1.2	E1112I	Neutral	0.104
BRCA1	P38398-1.2	E1112K	Neutral	0.035
BRCA1	P38398-1.2	E1112L	Neutral	0.104
BRCA1	P38398-1.2	E1112M	Neutral	0.075
BRCA1	P38398-1.2	E1112N	Neutral	0.037
BRCA1	P38398-1.2	E1112P	Neutral	0.059
BRCA1	P38398-1.2	E1112Q	Neutral	0.015
BRCA1	P38398-1.2	E1112R	Neutral	0.064
BRCA1	P38398-1.2	E1112S	Neutral	0.06
BRCA1	P38398-1.2	E1112T	Neutral	0.056
BRCA1	P38398-1.2	E1112V	Neutral	0.06
BRCA1	P38398-1.2	E1112W	Neutral	0.214
BRCA1	P38398-1.2	E1112Y	Neutral	0.107
BRCA1	P38398-1.2	Y1113A	Neutral	0.026
BRCA1	P38398-1.2	Y1113C	Neutral	0.017
BRCA1	P38398-1.2	Y1113D	Neutral	0.021
BRCA1	P38398-1.2	Y1113E	Neutral	0.01
BRCA1	P38398-1.2	Y1113F	Neutral	0.001
BRCA1	P38398-1.2	Y1113G	Neutral	0.054
BRCA1	P38398-1.2	Y1113H	Neutral	0.002
BRCA1	P38398-1.2	Y1113I	Neutral	0.005
BRCA1	P38398-1.2	Y1113K	Neutral	0.006
BRCA1	P38398-1.2	Y1113L	Neutral	0.005
BRCA1	P38398-1.2	Y1113M	Neutral	0.005
BRCA1	P38398-1.2	Y1113N	Neutral	0.013
BRCA1	P38398-1.2	Y1113P	Neutral	0.022
BRCA1	P38398-1.2	Y1113Q	Neutral	0.006
BRCA1	P38398-1.2	Y1113R	Neutral	0.006
BRCA1	P38398-1.2	Y1113S	Neutral	0.022
BRCA1	P38398-1.2	Y1113T	Neutral	0.015
BRCA1	P38398-1.2	Y1113V	Neutral	0.008
BRCA1	P38398-1.2	Y1113W	Neutral	0.002
BRCA1	P38398-1.2	E1114A	Neutral	0.193
BRCA1	P38398-1.2	E1114C	Neutral	0.316
BRCA1	P38398-1.2	E1114D	Neutral	0.046
BRCA1	P38398-1.2	E1114F	Neutral	0.252
BRCA1	P38398-1.2	E1114G	Neutral	0.346
BRCA1	P38398-1.2	E1114H	Neutral	0.074
BRCA1	P38398-1.2	E1114I	Neutral	0.209
BRCA1	P38398-1.2	E1114K	Neutral	0.076
BRCA1	P38398-1.2	E1114L	Neutral	0.209
BRCA1	P38398-1.2	E1114M	Neutral	0.157
BRCA1	P38398-1.2	E1114N	Neutral	0.082
BRCA1	P38398-1.2	E1114P	Neutral	0.125
BRCA1	P38398-1.2	E1114Q	Neutral	0.034
BRCA1	P38398-1.2	E1114R	Neutral	0.136
BRCA1	P38398-1.2	E1114S	Neutral	0.128
BRCA1	P38398-1.2	E1114T	Neutral	0.119
BRCA1	P38398-1.2	E1114V	Neutral	0.127
BRCA1	P38398-1.2	E1114W	Neutral	0.384
BRCA1	P38398-1.2	E1114Y	Neutral	0.214
BRCA1	P38398-1.2	E1115A	Neutral	0.005
BRCA1	P38398-1.2	E1115C	Neutral	0.01
BRCA1	P38398-1.2	E1115D	Neutral	0.001
BRCA1	P38398-1.2	E1115F	Neutral	0.007
BRCA1	P38398-1.2	E1115G	Neutral	0.012
BRCA1	P38398-1.2	E1115H	Neutral	0.002
BRCA1	P38398-1.2	E1115I	Neutral	0.006
BRCA1	P38398-1.2	E1115K	Neutral	0.002
BRCA1	P38398-1.2	E1115L	Neutral	0.006
BRCA1	P38398-1.2	E1115M	Neutral	0.004
BRCA1	P38398-1.2	E1115N	Neutral	0.002
BRCA1	P38398-1.2	E1115P	Neutral	0.003
BRCA1	P38398-1.2	E1115Q	Neutral	0.001
BRCA1	P38398-1.2	E1115R	Neutral	0.003
BRCA1	P38398-1.2	E1115S	Neutral	0.003
BRCA1	P38398-1.2	E1115T	Neutral	0.003
BRCA1	P38398-1.2	E1115V	Neutral	0.003
BRCA1	P38398-1.2	E1115W	Neutral	0.014
BRCA1	P38398-1.2	E1115Y	Neutral	0.006
BRCA1	P38398-1.2	V1116A	Neutral	0.007
BRCA1	P38398-1.2	V1116C	Neutral	0.007
BRCA1	P38398-1.2	V1116D	Neutral	0.012
BRCA1	P38398-1.2	V1116E	Neutral	0.007
BRCA1	P38398-1.2	V1116F	Neutral	0.009
BRCA1	P38398-1.2	V1116G	Neutral	0.032
BRCA1	P38398-1.2	V1116H	Neutral	0.012
BRCA1	P38398-1.2	V1116I	Neutral	0.002
BRCA1	P38398-1.2	V1116K	Neutral	0.012
BRCA1	P38398-1.2	V1116L	Neutral	0.003
BRCA1	P38398-1.2	V1116M	Neutral	0.003
BRCA1	P38398-1.2	V1116N	Neutral	0.011
BRCA1	P38398-1.2	V1116P	Neutral	0.009
BRCA1	P38398-1.2	V1116Q	Neutral	0.008
BRCA1	P38398-1.2	V1116R	Neutral	0.023
BRCA1	P38398-1.2	V1116S	Neutral	0.013
BRCA1	P38398-1.2	V1116T	Neutral	0.004
BRCA1	P38398-1.2	V1116W	Neutral	0.032
BRCA1	P38398-1.2	V1116Y	Neutral	0.01
BRCA1	P38398-1.2	V1117A	Neutral	0.011
BRCA1	P38398-1.2	V1117C	Neutral	0.01
BRCA1	P38398-1.2	V1117D	Neutral	0.018
BRCA1	P38398-1.2	V1117E	Neutral	0.01
BRCA1	P38398-1.2	V1117F	Neutral	0.013
BRCA1	P38398-1.2	V1117G	Neutral	0.046
BRCA1	P38398-1.2	V1117H	Neutral	0.018
BRCA1	P38398-1.2	V1117I	Neutral	0.002
BRCA1	P38398-1.2	V1117K	Neutral	0.018
BRCA1	P38398-1.2	V1117L	Neutral	0.005
BRCA1	P38398-1.2	V1117M	Neutral	0.005
BRCA1	P38398-1.2	V1117N	Neutral	0.016
BRCA1	P38398-1.2	V1117P	Neutral	0.013
BRCA1	P38398-1.2	V1117Q	Neutral	0.011
BRCA1	P38398-1.2	V1117R	Neutral	0.034
BRCA1	P38398-1.2	V1117S	Neutral	0.019
BRCA1	P38398-1.2	V1117T	Neutral	0.006
BRCA1	P38398-1.2	V1117W	Neutral	0.048
BRCA1	P38398-1.2	V1117Y	Neutral	0.015
BRCA1	P38398-1.2	Q1118A	Neutral	0.19
BRCA1	P38398-1.2	Q1118C	Neutral	0.239
BRCA1	P38398-1.2	Q1118D	Neutral	0.087
BRCA1	P38398-1.2	Q1118E	Neutral	0.03
BRCA1	P38398-1.2	Q1118F	Neutral	0.209
BRCA1	P38398-1.2	Q1118G	Neutral	0.341
BRCA1	P38398-1.2	Q1118H	Neutral	0.059
BRCA1	P38398-1.2	Q1118I	Neutral	0.172
BRCA1	P38398-1.2	Q1118K	Neutral	0.059
BRCA1	P38398-1.2	Q1118L	Neutral	0.126
BRCA1	P38398-1.2	Q1118M	Neutral	0.066
BRCA1	P38398-1.2	Q1118N	Neutral	0.079
BRCA1	P38398-1.2	Q1118P	Neutral	0.122
BRCA1	P38398-1.2	Q1118R	Neutral	0.078
BRCA1	P38398-1.2	Q1118S	Neutral	0.125
BRCA1	P38398-1.2	Q1118T	Neutral	0.116
BRCA1	P38398-1.2	Q1118V	Neutral	0.125
BRCA1	P38398-1.2	Q1118W	Neutral	0.253
BRCA1	P38398-1.2	Q1118Y	Neutral	0.129
BRCA1	P38398-1.2	T1119A	Neutral	0.065
BRCA1	P38398-1.2	T1119C	Neutral	0.061
BRCA1	P38398-1.2	T1119D	Neutral	0.054
BRCA1	P38398-1.2	T1119E	Neutral	0.073
BRCA1	P38398-1.2	T1119F	Neutral	0.166
BRCA1	P38398-1.2	T1119G	Neutral	0.179
BRCA1	P38398-1.2	T1119H	Neutral	0.123
BRCA1	P38398-1.2	T1119I	Neutral	0.098
BRCA1	P38398-1.2	T1119K	Neutral	0.122
BRCA1	P38398-1.2	T1119L	Neutral	0.098
BRCA1	P38398-1.2	T1119M	Neutral	0.099
BRCA1	P38398-1.2	T1119N	Neutral	0.039
BRCA1	P38398-1.2	T1119P	Neutral	0.056
BRCA1	P38398-1.2	T1119Q	Neutral	0.081
BRCA1	P38398-1.2	T1119R	Neutral	0.156
BRCA1	P38398-1.2	T1119S	Neutral	0.04
BRCA1	P38398-1.2	T1119V	Neutral	0.047
BRCA1	P38398-1.2	T1119W	Neutral	0.268
BRCA1	P38398-1.2	T1119Y	Neutral	0.188
BRCA1	P38398-1.2	V1120A	Pathogenic	0.731
BRCA1	P38398-1.2	V1120C	Pathogenic	0.722
BRCA1	P38398-1.2	V1120D	Pathogenic	0.823
BRCA1	P38398-1.2	V1120E	Pathogenic	0.722
BRCA1	P38398-1.2	V1120F	Pathogenic	0.767
BRCA1	P38398-1.2	V1120G	Pathogenic	0.925
BRCA1	P38398-1.2	V1120H	Pathogenic	0.822
BRCA1	P38398-1.2	V1120I	Neutral	0.375
BRCA1	P38398-1.2	V1120K	Pathogenic	0.821
BRCA1	P38398-1.2	V1120L	Pathogenic	0.555
BRCA1	P38398-1.2	V1120M	Pathogenic	0.557
BRCA1	P38398-1.2	V1120N	Pathogenic	0.807
BRCA1	P38398-1.2	V1120P	Pathogenic	0.773
BRCA1	P38398-1.2	V1120Q	Pathogenic	0.745
BRCA1	P38398-1.2	V1120R	Pathogenic	0.898
BRCA1	P38398-1.2	V1120S	Pathogenic	0.83
BRCA1	P38398-1.2	V1120T	Pathogenic	0.603
BRCA1	P38398-1.2	V1120W	Pathogenic	0.926
BRCA1	P38398-1.2	V1120Y	Pathogenic	0.791
BRCA1	P38398-1.2	N1121A	Neutral	0.012
BRCA1	P38398-1.2	N1121C	Neutral	0.011
BRCA1	P38398-1.2	N1121D	Neutral	0.002
BRCA1	P38398-1.2	N1121E	Neutral	0.004
BRCA1	P38398-1.2	N1121F	Neutral	0.021
BRCA1	P38398-1.2	N1121G	Neutral	0.009
BRCA1	P38398-1.2	N1121H	Neutral	0.003
BRCA1	P38398-1.2	N1121I	Neutral	0.016
BRCA1	P38398-1.2	N1121K	Neutral	0.007
BRCA1	P38398-1.2	N1121L	Neutral	0.016
BRCA1	P38398-1.2	N1121M	Neutral	0.012
BRCA1	P38398-1.2	N1121P	Neutral	0.007
BRCA1	P38398-1.2	N1121Q	Neutral	0.005
BRCA1	P38398-1.2	N1121R	Neutral	0.01
BRCA1	P38398-1.2	N1121S	Neutral	0.004
BRCA1	P38398-1.2	N1121T	Neutral	0.003
BRCA1	P38398-1.2	N1121V	Neutral	0.011
BRCA1	P38398-1.2	N1121W	Neutral	0.053
BRCA1	P38398-1.2	N1121Y	Neutral	0.017
BRCA1	P38398-1.2	T1122A	Neutral	0.04
BRCA1	P38398-1.2	T1122C	Neutral	0.038
BRCA1	P38398-1.2	T1122D	Neutral	0.034
BRCA1	P38398-1.2	T1122E	Neutral	0.046
BRCA1	P38398-1.2	T1122F	Neutral	0.108
BRCA1	P38398-1.2	T1122G	Neutral	0.117
BRCA1	P38398-1.2	T1122H	Neutral	0.079
BRCA1	P38398-1.2	T1122I	Neutral	0.062
BRCA1	P38398-1.2	T1122K	Neutral	0.078
BRCA1	P38398-1.2	T1122L	Neutral	0.062
BRCA1	P38398-1.2	T1122M	Neutral	0.062
BRCA1	P38398-1.2	T1122N	Neutral	0.024
BRCA1	P38398-1.2	T1122P	Neutral	0.035
BRCA1	P38398-1.2	T1122Q	Neutral	0.051
BRCA1	P38398-1.2	T1122R	Neutral	0.101
BRCA1	P38398-1.2	T1122S	Neutral	0.025
BRCA1	P38398-1.2	T1122V	Neutral	0.029
BRCA1	P38398-1.2	T1122W	Neutral	0.183
BRCA1	P38398-1.2	T1122Y	Neutral	0.123
BRCA1	P38398-1.2	D1123A	Pathogenic	0.87
BRCA1	P38398-1.2	D1123C	Pathogenic	0.862
BRCA1	P38398-1.2	D1123E	Pathogenic	0.583
BRCA1	P38398-1.2	D1123F	Pathogenic	0.936
BRCA1	P38398-1.2	D1123G	Pathogenic	0.877
BRCA1	P38398-1.2	D1123H	Pathogenic	0.834
BRCA1	P38398-1.2	D1123I	Pathogenic	0.92
BRCA1	P38398-1.2	D1123K	Pathogenic	0.881
BRCA1	P38398-1.2	D1123L	Pathogenic	0.943
BRCA1	P38398-1.2	D1123M	Pathogenic	0.921
BRCA1	P38398-1.2	D1123N	Pathogenic	0.601
BRCA1	P38398-1.2	D1123P	Pathogenic	0.735
BRCA1	P38398-1.2	D1123Q	Pathogenic	0.762
BRCA1	P38398-1.2	D1123R	Pathogenic	0.934
BRCA1	P38398-1.2	D1123S	Pathogenic	0.741
BRCA1	P38398-1.2	D1123T	Pathogenic	0.741
BRCA1	P38398-1.2	D1123V	Pathogenic	0.884
BRCA1	P38398-1.2	D1123W	Pathogenic	0.975
BRCA1	P38398-1.2	D1123Y	Pathogenic	0.944
BRCA1	P38398-1.2	F1124A	Pathogenic	0.858
BRCA1	P38398-1.2	F1124C	Pathogenic	0.801
BRCA1	P38398-1.2	F1124D	Pathogenic	0.834
BRCA1	P38398-1.2	F1124E	Pathogenic	0.771
BRCA1	P38398-1.2	F1124G	Pathogenic	0.93
BRCA1	P38398-1.2	F1124H	Pathogenic	0.575
BRCA1	P38398-1.2	F1124I	Neutral	0.459
BRCA1	P38398-1.2	F1124K	Pathogenic	0.653
BRCA1	P38398-1.2	F1124L	Neutral	0.459
BRCA1	P38398-1.2	F1124M	Neutral	0.457
BRCA1	P38398-1.2	F1124N	Pathogenic	0.818
BRCA1	P38398-1.2	F1124P	Pathogenic	0.884
BRCA1	P38398-1.2	F1124Q	Pathogenic	0.753
BRCA1	P38398-1.2	F1124R	Pathogenic	0.715
BRCA1	P38398-1.2	F1124S	Pathogenic	0.841
BRCA1	P38398-1.2	F1124T	Pathogenic	0.773
BRCA1	P38398-1.2	F1124V	Pathogenic	0.648
BRCA1	P38398-1.2	F1124W	Neutral	0.46
BRCA1	P38398-1.2	F1124Y	Neutral	0.201
BRCA1	P38398-1.2	S1125A	Neutral	0.324
BRCA1	P38398-1.2	S1125C	Pathogenic	0.533
BRCA1	P38398-1.2	S1125D	Neutral	0.471
BRCA1	P38398-1.2	S1125E	Pathogenic	0.572
BRCA1	P38398-1.2	S1125F	Pathogenic	0.828
BRCA1	P38398-1.2	S1125G	Pathogenic	0.514
BRCA1	P38398-1.2	S1125H	Pathogenic	0.703
BRCA1	P38398-1.2	S1125I	Pathogenic	0.79
BRCA1	P38398-1.2	S1125K	Pathogenic	0.702
BRCA1	P38398-1.2	S1125L	Pathogenic	0.79
BRCA1	P38398-1.2	S1125M	Pathogenic	0.726
BRCA1	P38398-1.2	S1125N	Neutral	0.41
BRCA1	P38398-1.2	S1125P	Pathogenic	0.557
BRCA1	P38398-1.2	S1125Q	Pathogenic	0.6
BRCA1	P38398-1.2	S1125R	Pathogenic	0.819
BRCA1	P38398-1.2	S1125T	Neutral	0.395
BRCA1	P38398-1.2	S1125V	Pathogenic	0.714
BRCA1	P38398-1.2	S1125W	Pathogenic	0.927
BRCA1	P38398-1.2	S1125Y	Pathogenic	0.848
BRCA1	P38398-1.2	P1126A	Pathogenic	0.869
BRCA1	P38398-1.2	P1126C	Pathogenic	0.9
BRCA1	P38398-1.2	P1126D	Pathogenic	0.799
BRCA1	P38398-1.2	P1126E	Pathogenic	0.856
BRCA1	P38398-1.2	P1126F	Pathogenic	0.969
BRCA1	P38398-1.2	P1126G	Pathogenic	0.935
BRCA1	P38398-1.2	P1126H	Pathogenic	0.914
BRCA1	P38398-1.2	P1126I	Pathogenic	0.945
BRCA1	P38398-1.2	P1126K	Pathogenic	0.913
BRCA1	P38398-1.2	P1126L	Pathogenic	0.945
BRCA1	P38398-1.2	P1126M	Pathogenic	0.924
BRCA1	P38398-1.2	P1126N	Pathogenic	0.865
BRCA1	P38398-1.2	P1126Q	Pathogenic	0.87
BRCA1	P38398-1.2	P1126R	Pathogenic	0.953
BRCA1	P38398-1.2	P1126S	Pathogenic	0.852
BRCA1	P38398-1.2	P1126T	Pathogenic	0.809
BRCA1	P38398-1.2	P1126V	Pathogenic	0.888
BRCA1	P38398-1.2	P1126W	Pathogenic	0.983
BRCA1	P38398-1.2	P1126Y	Pathogenic	0.962
BRCA1	P38398-1.2	Y1127A	Pathogenic	0.857
BRCA1	P38398-1.2	Y1127C	Pathogenic	0.799
BRCA1	P38398-1.2	Y1127D	Pathogenic	0.832
BRCA1	P38398-1.2	Y1127E	Pathogenic	0.698
BRCA1	P38398-1.2	Y1127F	Neutral	0.176
BRCA1	P38398-1.2	Y1127G	Pathogenic	0.929
BRCA1	P38398-1.2	Y1127H	Neutral	0.309
BRCA1	P38398-1.2	Y1127I	Pathogenic	0.538
BRCA1	P38398-1.2	Y1127K	Pathogenic	0.563
BRCA1	P38398-1.2	Y1127L	Pathogenic	0.539
BRCA1	P38398-1.2	Y1127M	Pathogenic	0.541
BRCA1	P38398-1.2	Y1127N	Pathogenic	0.755
BRCA1	P38398-1.2	Y1127P	Pathogenic	0.839
BRCA1	P38398-1.2	Y1127Q	Pathogenic	0.591
BRCA1	P38398-1.2	Y1127R	Pathogenic	0.568
BRCA1	P38398-1.2	Y1127S	Pathogenic	0.839
BRCA1	P38398-1.2	Y1127T	Pathogenic	0.77
BRCA1	P38398-1.2	Y1127V	Pathogenic	0.643
BRCA1	P38398-1.2	Y1127W	Neutral	0.302
BRCA1	P38398-1.2	L1128A	Neutral	0.327
BRCA1	P38398-1.2	L1128C	Neutral	0.244
BRCA1	P38398-1.2	L1128D	Neutral	0.454
BRCA1	P38398-1.2	L1128E	Neutral	0.28
BRCA1	P38398-1.2	L1128F	Neutral	0.111
BRCA1	P38398-1.2	L1128G	Pathogenic	0.687
BRCA1	P38398-1.2	L1128H	Neutral	0.244
BRCA1	P38398-1.2	L1128I	Neutral	0.045
BRCA1	P38398-1.2	L1128K	Neutral	0.197
BRCA1	P38398-1.2	L1128M	Neutral	0.045
BRCA1	P38398-1.2	L1128N	Neutral	0.342
BRCA1	P38398-1.2	L1128P	Neutral	0.378
BRCA1	P38398-1.2	L1128Q	Neutral	0.196
BRCA1	P38398-1.2	L1128R	Neutral	0.247
BRCA1	P38398-1.2	L1128S	Neutral	0.378
BRCA1	P38398-1.2	L1128T	Neutral	0.214
BRCA1	P38398-1.2	L1128V	Neutral	0.093
BRCA1	P38398-1.2	L1128W	Neutral	0.323
BRCA1	P38398-1.2	L1128Y	Neutral	0.168
BRCA1	P38398-1.2	I1129A	Neutral	0.461
BRCA1	P38398-1.2	I1129C	Neutral	0.362
BRCA1	P38398-1.2	I1129D	Pathogenic	0.504
BRCA1	P38398-1.2	I1129E	Neutral	0.406
BRCA1	P38398-1.2	I1129F	Neutral	0.18
BRCA1	P38398-1.2	I1129G	Pathogenic	0.794
BRCA1	P38398-1.2	I1129H	Neutral	0.362
BRCA1	P38398-1.2	I1129K	Neutral	0.383
BRCA1	P38398-1.2	I1129L	Neutral	0.077
BRCA1	P38398-1.2	I1129M	Neutral	0.106
BRCA1	P38398-1.2	I1129N	Neutral	0.477
BRCA1	P38398-1.2	I1129P	Pathogenic	0.517
BRCA1	P38398-1.2	I1129Q	Neutral	0.381
BRCA1	P38398-1.2	I1129R	Neutral	0.453
BRCA1	P38398-1.2	I1129S	Pathogenic	0.517
BRCA1	P38398-1.2	I1129T	Neutral	0.324
BRCA1	P38398-1.2	I1129V	Neutral	0.08
BRCA1	P38398-1.2	I1129W	Pathogenic	0.548
BRCA1	P38398-1.2	I1129Y	Neutral	0.262
BRCA1	P38398-1.2	S1130A	Neutral	0.046
BRCA1	P38398-1.2	S1130C	Neutral	0.104
BRCA1	P38398-1.2	S1130D	Neutral	0.083
BRCA1	P38398-1.2	S1130E	Neutral	0.119
BRCA1	P38398-1.2	S1130F	Neutral	0.327
BRCA1	P38398-1.2	S1130G	Neutral	0.097
BRCA1	P38398-1.2	S1130H	Neutral	0.193
BRCA1	P38398-1.2	S1130I	Neutral	0.276
BRCA1	P38398-1.2	S1130K	Neutral	0.193
BRCA1	P38398-1.2	S1130L	Neutral	0.276
BRCA1	P38398-1.2	S1130M	Neutral	0.211
BRCA1	P38398-1.2	S1130N	Neutral	0.066
BRCA1	P38398-1.2	S1130P	Neutral	0.113
BRCA1	P38398-1.2	S1130Q	Neutral	0.132
BRCA1	P38398-1.2	S1130R	Neutral	0.315
BRCA1	P38398-1.2	S1130T	Neutral	0.062
BRCA1	P38398-1.2	S1130V	Neutral	0.202
BRCA1	P38398-1.2	S1130W	Pathogenic	0.564
BRCA1	P38398-1.2	S1130Y	Neutral	0.361
BRCA1	P38398-1.2	D1131A	Pathogenic	0.725
BRCA1	P38398-1.2	D1131C	Pathogenic	0.711
BRCA1	P38398-1.2	D1131E	Neutral	0.354
BRCA1	P38398-1.2	D1131F	Pathogenic	0.852
BRCA1	P38398-1.2	D1131G	Pathogenic	0.738
BRCA1	P38398-1.2	D1131H	Pathogenic	0.663
BRCA1	P38398-1.2	D1131I	Pathogenic	0.818
BRCA1	P38398-1.2	D1131K	Pathogenic	0.744
BRCA1	P38398-1.2	D1131L	Pathogenic	0.867
BRCA1	P38398-1.2	D1131M	Pathogenic	0.82
BRCA1	P38398-1.2	D1131N	Neutral	0.371
BRCA1	P38398-1.2	D1131P	Pathogenic	0.522
BRCA1	P38398-1.2	D1131Q	Pathogenic	0.557
BRCA1	P38398-1.2	D1131R	Pathogenic	0.848
BRCA1	P38398-1.2	D1131S	Pathogenic	0.529
BRCA1	P38398-1.2	D1131T	Pathogenic	0.53
BRCA1	P38398-1.2	D1131V	Pathogenic	0.749
BRCA1	P38398-1.2	D1131W	Pathogenic	0.939
BRCA1	P38398-1.2	D1131Y	Pathogenic	0.87
BRCA1	P38398-1.2	N1132A	Neutral	0.219
BRCA1	P38398-1.2	N1132C	Neutral	0.207
BRCA1	P38398-1.2	N1132D	Neutral	0.053
BRCA1	P38398-1.2	N1132E	Neutral	0.088
BRCA1	P38398-1.2	N1132F	Neutral	0.329
BRCA1	P38398-1.2	N1132G	Neutral	0.172
BRCA1	P38398-1.2	N1132H	Neutral	0.075
BRCA1	P38398-1.2	N1132I	Neutral	0.277
BRCA1	P38398-1.2	N1132K	Neutral	0.146
BRCA1	P38398-1.2	N1132L	Neutral	0.278
BRCA1	P38398-1.2	N1132M	Neutral	0.212
BRCA1	P38398-1.2	N1132P	Neutral	0.143
BRCA1	P38398-1.2	N1132Q	Neutral	0.097
BRCA1	P38398-1.2	N1132R	Neutral	0.186
BRCA1	P38398-1.2	N1132S	Neutral	0.077
BRCA1	P38398-1.2	N1132T	Neutral	0.071
BRCA1	P38398-1.2	N1132V	Neutral	0.203
BRCA1	P38398-1.2	N1132W	Pathogenic	0.565
BRCA1	P38398-1.2	N1132Y	Neutral	0.283
BRCA1	P38398-1.2	L1133A	Neutral	0.324
BRCA1	P38398-1.2	L1133C	Neutral	0.241
BRCA1	P38398-1.2	L1133D	Neutral	0.45
BRCA1	P38398-1.2	L1133E	Neutral	0.277
BRCA1	P38398-1.2	L1133F	Neutral	0.109
BRCA1	P38398-1.2	L1133G	Pathogenic	0.684
BRCA1	P38398-1.2	L1133H	Neutral	0.241
BRCA1	P38398-1.2	L1133I	Neutral	0.044
BRCA1	P38398-1.2	L1133K	Neutral	0.195
BRCA1	P38398-1.2	L1133M	Neutral	0.044
BRCA1	P38398-1.2	L1133N	Neutral	0.338
BRCA1	P38398-1.2	L1133P	Neutral	0.375
BRCA1	P38398-1.2	L1133Q	Neutral	0.194
BRCA1	P38398-1.2	L1133R	Neutral	0.244
BRCA1	P38398-1.2	L1133S	Neutral	0.374
BRCA1	P38398-1.2	L1133T	Neutral	0.212
BRCA1	P38398-1.2	L1133V	Neutral	0.092
BRCA1	P38398-1.2	L1133W	Neutral	0.319
BRCA1	P38398-1.2	L1133Y	Neutral	0.166
BRCA1	P38398-1.2	E1134A	Pathogenic	0.953
BRCA1	P38398-1.2	E1134C	Pathogenic	0.975
BRCA1	P38398-1.2	E1134D	Pathogenic	0.801
BRCA1	P38398-1.2	E1134F	Pathogenic	0.966
BRCA1	P38398-1.2	E1134G	Pathogenic	0.978
BRCA1	P38398-1.2	E1134H	Pathogenic	0.871
BRCA1	P38398-1.2	E1134I	Pathogenic	0.957
BRCA1	P38398-1.2	E1134K	Pathogenic	0.873
BRCA1	P38398-1.2	E1134L	Pathogenic	0.957
BRCA1	P38398-1.2	E1134M	Pathogenic	0.94
BRCA1	P38398-1.2	E1134N	Pathogenic	0.882
BRCA1	P38398-1.2	E1134P	Pathogenic	0.923
BRCA1	P38398-1.2	E1134Q	Pathogenic	0.75
BRCA1	P38398-1.2	E1134R	Pathogenic	0.93
BRCA1	P38398-1.2	E1134S	Pathogenic	0.925
BRCA1	P38398-1.2	E1134T	Pathogenic	0.919
BRCA1	P38398-1.2	E1134V	Pathogenic	0.924
BRCA1	P38398-1.2	E1134W	Pathogenic	0.981
BRCA1	P38398-1.2	E1134Y	Pathogenic	0.958
BRCA1	P38398-1.2	Q1135A	Pathogenic	0.823
BRCA1	P38398-1.2	Q1135C	Pathogenic	0.862
BRCA1	P38398-1.2	Q1135D	Pathogenic	0.655
BRCA1	P38398-1.2	Q1135E	Neutral	0.381
BRCA1	P38398-1.2	Q1135F	Pathogenic	0.84
BRCA1	P38398-1.2	Q1135G	Pathogenic	0.911
BRCA1	P38398-1.2	Q1135H	Pathogenic	0.555
BRCA1	P38398-1.2	Q1135I	Pathogenic	0.805
BRCA1	P38398-1.2	Q1135K	Pathogenic	0.557
BRCA1	P38398-1.2	Q1135L	Pathogenic	0.741
BRCA1	P38398-1.2	Q1135M	Pathogenic	0.583
BRCA1	P38398-1.2	Q1135N	Pathogenic	0.63
BRCA1	P38398-1.2	Q1135P	Pathogenic	0.735
BRCA1	P38398-1.2	Q1135R	Pathogenic	0.626
BRCA1	P38398-1.2	Q1135S	Pathogenic	0.74
BRCA1	P38398-1.2	Q1135T	Pathogenic	0.723
BRCA1	P38398-1.2	Q1135V	Pathogenic	0.739
BRCA1	P38398-1.2	Q1135W	Pathogenic	0.871
BRCA1	P38398-1.2	Q1135Y	Pathogenic	0.747
BRCA1	P38398-1.2	P1136A	Pathogenic	0.715
BRCA1	P38398-1.2	P1136C	Pathogenic	0.773
BRCA1	P38398-1.2	P1136D	Pathogenic	0.601
BRCA1	P38398-1.2	P1136E	Pathogenic	0.692
BRCA1	P38398-1.2	P1136F	Pathogenic	0.923
BRCA1	P38398-1.2	P1136G	Pathogenic	0.845
BRCA1	P38398-1.2	P1136H	Pathogenic	0.801
BRCA1	P38398-1.2	P1136I	Pathogenic	0.867
BRCA1	P38398-1.2	P1136K	Pathogenic	0.799
BRCA1	P38398-1.2	P1136L	Pathogenic	0.868
BRCA1	P38398-1.2	P1136M	Pathogenic	0.821
BRCA1	P38398-1.2	P1136N	Pathogenic	0.708
BRCA1	P38398-1.2	P1136Q	Pathogenic	0.717
BRCA1	P38398-1.2	P1136R	Pathogenic	0.884
BRCA1	P38398-1.2	P1136S	Pathogenic	0.685
BRCA1	P38398-1.2	P1136T	Pathogenic	0.616
BRCA1	P38398-1.2	P1136V	Pathogenic	0.751
BRCA1	P38398-1.2	P1136W	Pathogenic	0.957
BRCA1	P38398-1.2	P1136Y	Pathogenic	0.906
BRCA1	P38398-1.2	M1137A	Pathogenic	0.522
BRCA1	P38398-1.2	M1137C	Neutral	0.421
BRCA1	P38398-1.2	M1137D	Pathogenic	0.565
BRCA1	P38398-1.2	M1137E	Neutral	0.378
BRCA1	P38398-1.2	M1137F	Neutral	0.216
BRCA1	P38398-1.2	M1137G	Pathogenic	0.774
BRCA1	P38398-1.2	M1137H	Neutral	0.336
BRCA1	P38398-1.2	M1137I	Neutral	0.13
BRCA1	P38398-1.2	M1137K	Neutral	0.277
BRCA1	P38398-1.2	M1137L	Neutral	0.094
BRCA1	P38398-1.2	M1137N	Neutral	0.448
BRCA1	P38398-1.2	M1137P	Neutral	0.488
BRCA1	P38398-1.2	M1137Q	Neutral	0.209
BRCA1	P38398-1.2	M1137R	Neutral	0.339
BRCA1	P38398-1.2	M1137S	Neutral	0.487
BRCA1	P38398-1.2	M1137T	Neutral	0.38
BRCA1	P38398-1.2	M1137V	Neutral	0.188
BRCA1	P38398-1.2	M1137W	Neutral	0.423
BRCA1	P38398-1.2	M1137Y	Neutral	0.313
BRCA1	P38398-1.2	G1138A	Neutral	0.416
BRCA1	P38398-1.2	G1138C	Pathogenic	0.762
BRCA1	P38398-1.2	G1138D	Pathogenic	0.634
BRCA1	P38398-1.2	G1138E	Pathogenic	0.788
BRCA1	P38398-1.2	G1138F	Pathogenic	0.903
BRCA1	P38398-1.2	G1138H	Pathogenic	0.821
BRCA1	P38398-1.2	G1138I	Pathogenic	0.913
BRCA1	P38398-1.2	G1138K	Pathogenic	0.868
BRCA1	P38398-1.2	G1138L	Pathogenic	0.913
BRCA1	P38398-1.2	G1138M	Pathogenic	0.881
BRCA1	P38398-1.2	G1138N	Pathogenic	0.574
BRCA1	P38398-1.2	G1138P	Pathogenic	0.709
BRCA1	P38398-1.2	G1138Q	Pathogenic	0.808
BRCA1	P38398-1.2	G1138R	Pathogenic	0.898
BRCA1	P38398-1.2	G1138S	Neutral	0.45
BRCA1	P38398-1.2	G1138T	Pathogenic	0.725
BRCA1	P38398-1.2	G1138V	Pathogenic	0.829
BRCA1	P38398-1.2	G1138W	Pathogenic	0.923
BRCA1	P38398-1.2	G1138Y	Pathogenic	0.916
BRCA1	P38398-1.2	S1139A	Neutral	0.034
BRCA1	P38398-1.2	S1139C	Neutral	0.076
BRCA1	P38398-1.2	S1139D	Neutral	0.061
BRCA1	P38398-1.2	S1139E	Neutral	0.088
BRCA1	P38398-1.2	S1139F	Neutral	0.258
BRCA1	P38398-1.2	S1139G	Neutral	0.071
BRCA1	P38398-1.2	S1139H	Neutral	0.146
BRCA1	P38398-1.2	S1139I	Neutral	0.214
BRCA1	P38398-1.2	S1139K	Neutral	0.146
BRCA1	P38398-1.2	S1139L	Neutral	0.215
BRCA1	P38398-1.2	S1139M	Neutral	0.161
BRCA1	P38398-1.2	S1139N	Neutral	0.048
BRCA1	P38398-1.2	S1139P	Neutral	0.083
BRCA1	P38398-1.2	S1139Q	Neutral	0.098
BRCA1	P38398-1.2	S1139R	Neutral	0.247
BRCA1	P38398-1.2	S1139T	Neutral	0.045
BRCA1	P38398-1.2	S1139V	Neutral	0.153
BRCA1	P38398-1.2	S1139W	Neutral	0.481
BRCA1	P38398-1.2	S1139Y	Neutral	0.288
BRCA1	P38398-1.2	S1140A	Neutral	0.031
BRCA1	P38398-1.2	S1140C	Neutral	0.071
BRCA1	P38398-1.2	S1140D	Neutral	0.056
BRCA1	P38398-1.2	S1140E	Neutral	0.082
BRCA1	P38398-1.2	S1140F	Neutral	0.243
BRCA1	P38398-1.2	S1140G	Neutral	0.066
BRCA1	P38398-1.2	S1140H	Neutral	0.136
BRCA1	P38398-1.2	S1140I	Neutral	0.201
BRCA1	P38398-1.2	S1140K	Neutral	0.136
BRCA1	P38398-1.2	S1140L	Neutral	0.201
BRCA1	P38398-1.2	S1140M	Neutral	0.15
BRCA1	P38398-1.2	S1140N	Neutral	0.044
BRCA1	P38398-1.2	S1140P	Neutral	0.077
BRCA1	P38398-1.2	S1140Q	Neutral	0.091
BRCA1	P38398-1.2	S1140R	Neutral	0.232
BRCA1	P38398-1.2	S1140T	Neutral	0.042
BRCA1	P38398-1.2	S1140V	Neutral	0.143
BRCA1	P38398-1.2	S1140W	Neutral	0.46
BRCA1	P38398-1.2	S1140Y	Neutral	0.272
BRCA1	P38398-1.2	H1141A	Neutral	0.027
BRCA1	P38398-1.2	H1141C	Neutral	0.025
BRCA1	P38398-1.2	H1141D	Neutral	0.011
BRCA1	P38398-1.2	H1141E	Neutral	0.005
BRCA1	P38398-1.2	H1141F	Neutral	0.009
BRCA1	P38398-1.2	H1141G	Neutral	0.04
BRCA1	P38398-1.2	H1141I	Neutral	0.014
BRCA1	P38398-1.2	H1141K	Neutral	0.009
BRCA1	P38398-1.2	H1141L	Neutral	0.014
BRCA1	P38398-1.2	H1141M	Neutral	0.01
BRCA1	P38398-1.2	H1141N	Neutral	0.005
BRCA1	P38398-1.2	H1141P	Neutral	0.016
BRCA1	P38398-1.2	H1141Q	Neutral	0.005
BRCA1	P38398-1.2	H1141R	Neutral	0.008
BRCA1	P38398-1.2	H1141S	Neutral	0.016
BRCA1	P38398-1.2	H1141T	Neutral	0.015
BRCA1	P38398-1.2	H1141V	Neutral	0.016
BRCA1	P38398-1.2	H1141W	Neutral	0.023
BRCA1	P38398-1.2	H1141Y	Neutral	0.003
BRCA1	P38398-1.2	A1142C	Neutral	0.058
BRCA1	P38398-1.2	A1142D	Neutral	0.123
BRCA1	P38398-1.2	A1142E	Neutral	0.127
BRCA1	P38398-1.2	A1142F	Neutral	0.27
BRCA1	P38398-1.2	A1142G	Neutral	0.058
BRCA1	P38398-1.2	A1142H	Neutral	0.206
BRCA1	P38398-1.2	A1142I	Neutral	0.168
BRCA1	P38398-1.2	A1142K	Neutral	0.205
BRCA1	P38398-1.2	A1142L	Neutral	0.168
BRCA1	P38398-1.2	A1142M	Neutral	0.169
BRCA1	P38398-1.2	A1142N	Neutral	0.136
BRCA1	P38398-1.2	A1142P	Neutral	0.088
BRCA1	P38398-1.2	A1142Q	Neutral	0.141
BRCA1	P38398-1.2	A1142R	Neutral	0.256
BRCA1	P38398-1.2	A1142S	Neutral	0.031
BRCA1	P38398-1.2	A1142T	Neutral	0.067
BRCA1	P38398-1.2	A1142V	Neutral	0.085
BRCA1	P38398-1.2	A1142W	Neutral	0.496
BRCA1	P38398-1.2	A1142Y	Neutral	0.301
BRCA1	P38398-1.2	S1143A	Neutral	0.381
BRCA1	P38398-1.2	S1143C	Pathogenic	0.595
BRCA1	P38398-1.2	S1143D	Pathogenic	0.534
BRCA1	P38398-1.2	S1143E	Pathogenic	0.631
BRCA1	P38398-1.2	S1143F	Pathogenic	0.861
BRCA1	P38398-1.2	S1143G	Pathogenic	0.576
BRCA1	P38398-1.2	S1143H	Pathogenic	0.752
BRCA1	P38398-1.2	S1143I	Pathogenic	0.829
BRCA1	P38398-1.2	S1143K	Pathogenic	0.752
BRCA1	P38398-1.2	S1143L	Pathogenic	0.829
BRCA1	P38398-1.2	S1143M	Pathogenic	0.773
BRCA1	P38398-1.2	S1143N	Neutral	0.472
BRCA1	P38398-1.2	S1143P	Pathogenic	0.617
BRCA1	P38398-1.2	S1143Q	Pathogenic	0.659
BRCA1	P38398-1.2	S1143R	Pathogenic	0.853
BRCA1	P38398-1.2	S1143T	Neutral	0.456
BRCA1	P38398-1.2	S1143V	Pathogenic	0.762
BRCA1	P38398-1.2	S1143W	Pathogenic	0.943
BRCA1	P38398-1.2	S1143Y	Pathogenic	0.878
BRCA1	P38398-1.2	Q1144A	Pathogenic	0.966
BRCA1	P38398-1.2	Q1144C	Pathogenic	0.975
BRCA1	P38398-1.2	Q1144D	Pathogenic	0.921
BRCA1	P38398-1.2	Q1144E	Pathogenic	0.791
BRCA1	P38398-1.2	Q1144F	Pathogenic	0.97
BRCA1	P38398-1.2	Q1144G	Pathogenic	0.984
BRCA1	P38398-1.2	Q1144H	Pathogenic	0.885
BRCA1	P38398-1.2	Q1144I	Pathogenic	0.962
BRCA1	P38398-1.2	Q1144K	Pathogenic	0.885
BRCA1	P38398-1.2	Q1144L	Pathogenic	0.946
BRCA1	P38398-1.2	Q1144M	Pathogenic	0.896
BRCA1	P38398-1.2	Q1144N	Pathogenic	0.913
BRCA1	P38398-1.2	Q1144P	Pathogenic	0.944
BRCA1	P38398-1.2	Q1144R	Pathogenic	0.911
BRCA1	P38398-1.2	Q1144S	Pathogenic	0.946
BRCA1	P38398-1.2	Q1144T	Pathogenic	0.941
BRCA1	P38398-1.2	Q1144V	Pathogenic	0.946
BRCA1	P38398-1.2	Q1144W	Pathogenic	0.976
BRCA1	P38398-1.2	Q1144Y	Pathogenic	0.948
BRCA1	P38398-1.2	V1145A	Pathogenic	0.654
BRCA1	P38398-1.2	V1145C	Pathogenic	0.643
BRCA1	P38398-1.2	V1145D	Pathogenic	0.764
BRCA1	P38398-1.2	V1145E	Pathogenic	0.643
BRCA1	P38398-1.2	V1145F	Pathogenic	0.696
BRCA1	P38398-1.2	V1145G	Pathogenic	0.895
BRCA1	P38398-1.2	V1145H	Pathogenic	0.763
BRCA1	P38398-1.2	V1145I	Neutral	0.295
BRCA1	P38398-1.2	V1145K	Pathogenic	0.761
BRCA1	P38398-1.2	V1145L	Neutral	0.464
BRCA1	P38398-1.2	V1145M	Neutral	0.467
BRCA1	P38398-1.2	V1145N	Pathogenic	0.744
BRCA1	P38398-1.2	V1145P	Pathogenic	0.703
BRCA1	P38398-1.2	V1145Q	Pathogenic	0.67
BRCA1	P38398-1.2	V1145R	Pathogenic	0.86
BRCA1	P38398-1.2	V1145S	Pathogenic	0.773
BRCA1	P38398-1.2	V1145T	Pathogenic	0.514
BRCA1	P38398-1.2	V1145W	Pathogenic	0.897
BRCA1	P38398-1.2	V1145Y	Pathogenic	0.725
BRCA1	P38398-1.2	C1146A	Pathogenic	0.967
BRCA1	P38398-1.2	C1146D	Pathogenic	0.985
BRCA1	P38398-1.2	C1146E	Pathogenic	0.993
BRCA1	P38398-1.2	C1146F	Pathogenic	0.992
BRCA1	P38398-1.2	C1146G	Pathogenic	0.993
BRCA1	P38398-1.2	C1146H	Pathogenic	0.992
BRCA1	P38398-1.2	C1146I	Pathogenic	0.985
BRCA1	P38398-1.2	C1146K	Pathogenic	0.994
BRCA1	P38398-1.2	C1146L	Pathogenic	0.985
BRCA1	P38398-1.2	C1146M	Pathogenic	0.985
BRCA1	P38398-1.2	C1146N	Pathogenic	0.986
BRCA1	P38398-1.2	C1146P	Pathogenic	0.985
BRCA1	P38398-1.2	C1146Q	Pathogenic	0.991
BRCA1	P38398-1.2	C1146R	Pathogenic	0.996
BRCA1	P38398-1.2	C1146S	Pathogenic	0.974
BRCA1	P38398-1.2	C1146T	Pathogenic	0.97
BRCA1	P38398-1.2	C1146V	Pathogenic	0.977
BRCA1	P38398-1.2	C1146W	Pathogenic	0.995
BRCA1	P38398-1.2	C1146Y	Pathogenic	0.993
BRCA1	P38398-1.2	S1147A	Pathogenic	0.925
BRCA1	P38398-1.2	S1147C	Pathogenic	0.967
BRCA1	P38398-1.2	S1147D	Pathogenic	0.958
BRCA1	P38398-1.2	S1147E	Pathogenic	0.972
BRCA1	P38398-1.2	S1147F	Pathogenic	0.992
BRCA1	P38398-1.2	S1147G	Pathogenic	0.965
BRCA1	P38398-1.2	S1147H	Pathogenic	0.984
BRCA1	P38398-1.2	S1147I	Pathogenic	0.99
BRCA1	P38398-1.2	S1147K	Pathogenic	0.984
BRCA1	P38398-1.2	S1147L	Pathogenic	0.99
BRCA1	P38398-1.2	S1147M	Pathogenic	0.986
BRCA1	P38398-1.2	S1147N	Pathogenic	0.947
BRCA1	P38398-1.2	S1147P	Pathogenic	0.97
BRCA1	P38398-1.2	S1147Q	Pathogenic	0.975
BRCA1	P38398-1.2	S1147R	Pathogenic	0.992
BRCA1	P38398-1.2	S1147T	Pathogenic	0.944
BRCA1	P38398-1.2	S1147V	Pathogenic	0.985
BRCA1	P38398-1.2	S1147W	Pathogenic	0.997
BRCA1	P38398-1.2	S1147Y	Pathogenic	0.993
BRCA1	P38398-1.2	E1148A	Pathogenic	0.976
BRCA1	P38398-1.2	E1148C	Pathogenic	0.987
BRCA1	P38398-1.2	E1148D	Pathogenic	0.891
BRCA1	P38398-1.2	E1148F	Pathogenic	0.983
BRCA1	P38398-1.2	E1148G	Pathogenic	0.989
BRCA1	P38398-1.2	E1148H	Pathogenic	0.932
BRCA1	P38398-1.2	E1148I	Pathogenic	0.978
BRCA1	P38398-1.2	E1148K	Pathogenic	0.933
BRCA1	P38398-1.2	E1148L	Pathogenic	0.978
BRCA1	P38398-1.2	E1148M	Pathogenic	0.969
BRCA1	P38398-1.2	E1148N	Pathogenic	0.938
BRCA1	P38398-1.2	E1148P	Pathogenic	0.96
BRCA1	P38398-1.2	E1148Q	Pathogenic	0.858
BRCA1	P38398-1.2	E1148R	Pathogenic	0.964
BRCA1	P38398-1.2	E1148S	Pathogenic	0.961
BRCA1	P38398-1.2	E1148T	Pathogenic	0.958
BRCA1	P38398-1.2	E1148V	Pathogenic	0.961
BRCA1	P38398-1.2	E1148W	Pathogenic	0.991
BRCA1	P38398-1.2	E1148Y	Pathogenic	0.979
BRCA1	P38398-1.2	T1149A	Pathogenic	0.986
BRCA1	P38398-1.2	T1149C	Pathogenic	0.985
BRCA1	P38398-1.2	T1149D	Pathogenic	0.983
BRCA1	P38398-1.2	T1149E	Pathogenic	0.988
BRCA1	P38398-1.2	T1149F	Pathogenic	0.995
BRCA1	P38398-1.2	T1149G	Pathogenic	0.995
BRCA1	P38398-1.2	T1149H	Pathogenic	0.993
BRCA1	P38398-1.2	T1149I	Pathogenic	0.991
BRCA1	P38398-1.2	T1149K	Pathogenic	0.993
BRCA1	P38398-1.2	T1149L	Pathogenic	0.991
BRCA1	P38398-1.2	T1149M	Pathogenic	0.991
BRCA1	P38398-1.2	T1149N	Pathogenic	0.976
BRCA1	P38398-1.2	T1149P	Pathogenic	0.984
BRCA1	P38398-1.2	T1149Q	Pathogenic	0.989
BRCA1	P38398-1.2	T1149R	Pathogenic	0.995
BRCA1	P38398-1.2	T1149S	Pathogenic	0.977
BRCA1	P38398-1.2	T1149V	Pathogenic	0.981
BRCA1	P38398-1.2	T1149W	Pathogenic	0.997
BRCA1	P38398-1.2	T1149Y	Pathogenic	0.996
BRCA1	P38398-1.2	P1150A	Pathogenic	0.991
BRCA1	P38398-1.2	P1150C	Pathogenic	0.993
BRCA1	P38398-1.2	P1150D	Pathogenic	0.985
BRCA1	P38398-1.2	P1150E	Pathogenic	0.99
BRCA1	P38398-1.2	P1150F	Pathogenic	0.998
BRCA1	P38398-1.2	P1150G	Pathogenic	0.996
BRCA1	P38398-1.2	P1150H	Pathogenic	0.994
BRCA1	P38398-1.2	P1150I	Pathogenic	0.996
BRCA1	P38398-1.2	P1150K	Pathogenic	0.994
BRCA1	P38398-1.2	P1150L	Pathogenic	0.996
BRCA1	P38398-1.2	P1150M	Pathogenic	0.995
BRCA1	P38398-1.2	P1150N	Pathogenic	0.991
BRCA1	P38398-1.2	P1150Q	Pathogenic	0.991
BRCA1	P38398-1.2	P1150R	Pathogenic	0.997
BRCA1	P38398-1.2	P1150S	Pathogenic	0.989
BRCA1	P38398-1.2	P1150T	Pathogenic	0.986
BRCA1	P38398-1.2	P1150V	Pathogenic	0.992
BRCA1	P38398-1.2	P1150W	Pathogenic	0.999
BRCA1	P38398-1.2	P1150Y	Pathogenic	0.998
BRCA1	P38398-1.2	D1151A	Pathogenic	0.975
BRCA1	P38398-1.2	D1151C	Pathogenic	0.973
BRCA1	P38398-1.2	D1151E	Pathogenic	0.889
BRCA1	P38398-1.2	D1151F	Pathogenic	0.988
BRCA1	P38398-1.2	D1151G	Pathogenic	0.976
BRCA1	P38398-1.2	D1151H	Pathogenic	0.966
BRCA1	P38398-1.2	D1151I	Pathogenic	0.985
BRCA1	P38398-1.2	D1151K	Pathogenic	0.977
BRCA1	P38398-1.2	D1151L	Pathogenic	0.99
BRCA1	P38398-1.2	D1151M	Pathogenic	0.985
BRCA1	P38398-1.2	D1151N	Pathogenic	0.896
BRCA1	P38398-1.2	D1151P	Pathogenic	0.941
BRCA1	P38398-1.2	D1151Q	Pathogenic	0.948
BRCA1	P38398-1.2	D1151R	Pathogenic	0.988
BRCA1	P38398-1.2	D1151S	Pathogenic	0.942
BRCA1	P38398-1.2	D1151T	Pathogenic	0.943
BRCA1	P38398-1.2	D1151V	Pathogenic	0.978
BRCA1	P38398-1.2	D1151W	Pathogenic	0.996
BRCA1	P38398-1.2	D1151Y	Pathogenic	0.99
BRCA1	P38398-1.2	D1152A	Pathogenic	0.851
BRCA1	P38398-1.2	D1152C	Pathogenic	0.842
BRCA1	P38398-1.2	D1152E	Pathogenic	0.543
BRCA1	P38398-1.2	D1152F	Pathogenic	0.926
BRCA1	P38398-1.2	D1152G	Pathogenic	0.859
BRCA1	P38398-1.2	D1152H	Pathogenic	0.81
BRCA1	P38398-1.2	D1152I	Pathogenic	0.907
BRCA1	P38398-1.2	D1152K	Pathogenic	0.863
BRCA1	P38398-1.2	D1152L	Pathogenic	0.934
BRCA1	P38398-1.2	D1152M	Pathogenic	0.908
BRCA1	P38398-1.2	D1152N	Pathogenic	0.561
BRCA1	P38398-1.2	D1152P	Pathogenic	0.703
BRCA1	P38398-1.2	D1152Q	Pathogenic	0.732
BRCA1	P38398-1.2	D1152R	Pathogenic	0.924
BRCA1	P38398-1.2	D1152S	Pathogenic	0.708
BRCA1	P38398-1.2	D1152T	Pathogenic	0.709
BRCA1	P38398-1.2	D1152V	Pathogenic	0.866
BRCA1	P38398-1.2	D1152W	Pathogenic	0.971
BRCA1	P38398-1.2	D1152Y	Pathogenic	0.935
BRCA1	P38398-1.2	L1153A	Pathogenic	0.992
BRCA1	P38398-1.2	L1153C	Pathogenic	0.988
BRCA1	P38398-1.2	L1153D	Pathogenic	0.995
BRCA1	P38398-1.2	L1153E	Pathogenic	0.99
BRCA1	P38398-1.2	L1153F	Pathogenic	0.969
BRCA1	P38398-1.2	L1153G	Pathogenic	0.998
BRCA1	P38398-1.2	L1153H	Pathogenic	0.988
BRCA1	P38398-1.2	L1153I	Pathogenic	0.922
BRCA1	P38398-1.2	L1153K	Pathogenic	0.984
BRCA1	P38398-1.2	L1153M	Pathogenic	0.921
BRCA1	P38398-1.2	L1153N	Pathogenic	0.992
BRCA1	P38398-1.2	L1153P	Pathogenic	0.993
BRCA1	P38398-1.2	L1153Q	Pathogenic	0.984
BRCA1	P38398-1.2	L1153R	Pathogenic	0.988
BRCA1	P38398-1.2	L1153S	Pathogenic	0.993
BRCA1	P38398-1.2	L1153T	Pathogenic	0.985
BRCA1	P38398-1.2	L1153V	Pathogenic	0.962
BRCA1	P38398-1.2	L1153W	Pathogenic	0.992
BRCA1	P38398-1.2	L1153Y	Pathogenic	0.981
BRCA1	P38398-1.2	L1154A	Pathogenic	0.971
BRCA1	P38398-1.2	L1154C	Pathogenic	0.956
BRCA1	P38398-1.2	L1154D	Pathogenic	0.983
BRCA1	P38398-1.2	L1154E	Pathogenic	0.964
BRCA1	P38398-1.2	L1154F	Pathogenic	0.895
BRCA1	P38398-1.2	L1154G	Pathogenic	0.993
BRCA1	P38398-1.2	L1154H	Pathogenic	0.957
BRCA1	P38398-1.2	L1154I	Pathogenic	0.762
BRCA1	P38398-1.2	L1154K	Pathogenic	0.944
BRCA1	P38398-1.2	L1154M	Pathogenic	0.761
BRCA1	P38398-1.2	L1154N	Pathogenic	0.972
BRCA1	P38398-1.2	L1154P	Pathogenic	0.976
BRCA1	P38398-1.2	L1154Q	Pathogenic	0.943
BRCA1	P38398-1.2	L1154R	Pathogenic	0.957
BRCA1	P38398-1.2	L1154S	Pathogenic	0.976
BRCA1	P38398-1.2	L1154T	Pathogenic	0.949
BRCA1	P38398-1.2	L1154V	Pathogenic	0.875
BRCA1	P38398-1.2	L1154W	Pathogenic	0.97
BRCA1	P38398-1.2	L1154Y	Pathogenic	0.932
BRCA1	P38398-1.2	D1155A	Neutral	0.044
BRCA1	P38398-1.2	D1155C	Neutral	0.041
BRCA1	P38398-1.2	D1155E	Neutral	0.009
BRCA1	P38398-1.2	D1155F	Neutral	0.09
BRCA1	P38398-1.2	D1155G	Neutral	0.046
BRCA1	P38398-1.2	D1155H	Neutral	0.033
BRCA1	P38398-1.2	D1155I	Neutral	0.072
BRCA1	P38398-1.2	D1155K	Neutral	0.048
BRCA1	P38398-1.2	D1155L	Neutral	0.101
BRCA1	P38398-1.2	D1155M	Neutral	0.073
BRCA1	P38398-1.2	D1155N	Neutral	0.01
BRCA1	P38398-1.2	D1155P	Neutral	0.019
BRCA1	P38398-1.2	D1155Q	Neutral	0.021
BRCA1	P38398-1.2	D1155R	Neutral	0.088
BRCA1	P38398-1.2	D1155S	Neutral	0.019
BRCA1	P38398-1.2	D1155T	Neutral	0.019
BRCA1	P38398-1.2	D1155V	Neutral	0.049
BRCA1	P38398-1.2	D1155W	Neutral	0.209
BRCA1	P38398-1.2	D1155Y	Neutral	0.103
BRCA1	P38398-1.2	D1156A	Neutral	0.459
BRCA1	P38398-1.2	D1156C	Neutral	0.442
BRCA1	P38398-1.2	D1156E	Neutral	0.15
BRCA1	P38398-1.2	D1156F	Pathogenic	0.649
BRCA1	P38398-1.2	D1156G	Neutral	0.475
BRCA1	P38398-1.2	D1156H	Neutral	0.388
BRCA1	P38398-1.2	D1156I	Pathogenic	0.592
BRCA1	P38398-1.2	D1156K	Neutral	0.483
BRCA1	P38398-1.2	D1156L	Pathogenic	0.677
BRCA1	P38398-1.2	D1156M	Pathogenic	0.595
BRCA1	P38398-1.2	D1156N	Neutral	0.16
BRCA1	P38398-1.2	D1156P	Neutral	0.26
BRCA1	P38398-1.2	D1156Q	Neutral	0.288
BRCA1	P38398-1.2	D1156R	Pathogenic	0.643
BRCA1	P38398-1.2	D1156S	Neutral	0.265
BRCA1	P38398-1.2	D1156T	Neutral	0.266
BRCA1	P38398-1.2	D1156V	Neutral	0.49
BRCA1	P38398-1.2	D1156W	Pathogenic	0.831
BRCA1	P38398-1.2	D1156Y	Pathogenic	0.683
BRCA1	P38398-1.2	G1157A	Neutral	0.018
BRCA1	P38398-1.2	G1157C	Neutral	0.076
BRCA1	P38398-1.2	G1157D	Neutral	0.042
BRCA1	P38398-1.2	G1157E	Neutral	0.087
BRCA1	P38398-1.2	G1157F	Neutral	0.193
BRCA1	P38398-1.2	G1157H	Neutral	0.105
BRCA1	P38398-1.2	G1157I	Neutral	0.212
BRCA1	P38398-1.2	G1157K	Neutral	0.144
BRCA1	P38398-1.2	G1157L	Neutral	0.213
BRCA1	P38398-1.2	G1157M	Neutral	0.159
BRCA1	P38398-1.2	G1157N	Neutral	0.033
BRCA1	P38398-1.2	G1157P	Neutral	0.059
BRCA1	P38398-1.2	G1157Q	Neutral	0.097
BRCA1	P38398-1.2	G1157R	Neutral	0.184
BRCA1	P38398-1.2	G1157S	Neutral	0.021
BRCA1	P38398-1.2	G1157T	Neutral	0.063
BRCA1	P38398-1.2	G1157V	Neutral	0.11
BRCA1	P38398-1.2	G1157W	Neutral	0.235
BRCA1	P38398-1.2	G1157Y	Neutral	0.217
BRCA1	P38398-1.2	E1158A	Neutral	0.295
BRCA1	P38398-1.2	E1158C	Neutral	0.447
BRCA1	P38398-1.2	E1158D	Neutral	0.077
BRCA1	P38398-1.2	E1158F	Neutral	0.372
BRCA1	P38398-1.2	E1158G	Neutral	0.481
BRCA1	P38398-1.2	E1158H	Neutral	0.123
BRCA1	P38398-1.2	E1158I	Neutral	0.316
BRCA1	P38398-1.2	E1158K	Neutral	0.125
BRCA1	P38398-1.2	E1158L	Neutral	0.317
BRCA1	P38398-1.2	E1158M	Neutral	0.245
BRCA1	P38398-1.2	E1158N	Neutral	0.135
BRCA1	P38398-1.2	E1158P	Neutral	0.2
BRCA1	P38398-1.2	E1158Q	Neutral	0.059
BRCA1	P38398-1.2	E1158R	Neutral	0.216
BRCA1	P38398-1.2	E1158S	Neutral	0.204
BRCA1	P38398-1.2	E1158T	Neutral	0.191
BRCA1	P38398-1.2	E1158V	Neutral	0.203
BRCA1	P38398-1.2	E1158W	Pathogenic	0.522
BRCA1	P38398-1.2	E1158Y	Neutral	0.323
BRCA1	P38398-1.2	I1159A	Neutral	0.292
BRCA1	P38398-1.2	I1159C	Neutral	0.215
BRCA1	P38398-1.2	I1159D	Neutral	0.329
BRCA1	P38398-1.2	I1159E	Neutral	0.248
BRCA1	P38398-1.2	I1159F	Neutral	0.096
BRCA1	P38398-1.2	I1159G	Pathogenic	0.651
BRCA1	P38398-1.2	I1159H	Neutral	0.215
BRCA1	P38398-1.2	I1159K	Neutral	0.231
BRCA1	P38398-1.2	I1159L	Neutral	0.039
BRCA1	P38398-1.2	I1159M	Neutral	0.054
BRCA1	P38398-1.2	I1159N	Neutral	0.306
BRCA1	P38398-1.2	I1159P	Neutral	0.341
BRCA1	P38398-1.2	I1159Q	Neutral	0.229
BRCA1	P38398-1.2	I1159R	Neutral	0.286
BRCA1	P38398-1.2	I1159S	Neutral	0.34
BRCA1	P38398-1.2	I1159T	Neutral	0.188
BRCA1	P38398-1.2	I1159V	Neutral	0.04
BRCA1	P38398-1.2	I1159W	Neutral	0.369
BRCA1	P38398-1.2	I1159Y	Neutral	0.147
BRCA1	P38398-1.2	K1160A	Pathogenic	0.85
BRCA1	P38398-1.2	K1160C	Pathogenic	0.884
BRCA1	P38398-1.2	K1160D	Pathogenic	0.773
BRCA1	P38398-1.2	K1160E	Pathogenic	0.524
BRCA1	P38398-1.2	K1160F	Pathogenic	0.716
BRCA1	P38398-1.2	K1160G	Pathogenic	0.926
BRCA1	P38398-1.2	K1160H	Pathogenic	0.648
BRCA1	P38398-1.2	K1160I	Pathogenic	0.763
BRCA1	P38398-1.2	K1160L	Pathogenic	0.692
BRCA1	P38398-1.2	K1160M	Pathogenic	0.612
BRCA1	P38398-1.2	K1160N	Pathogenic	0.679
BRCA1	P38398-1.2	K1160P	Pathogenic	0.772
BRCA1	P38398-1.2	K1160Q	Neutral	0.494
BRCA1	P38398-1.2	K1160R	Neutral	0.366
BRCA1	P38398-1.2	K1160S	Pathogenic	0.777
BRCA1	P38398-1.2	K1160T	Pathogenic	0.762
BRCA1	P38398-1.2	K1160V	Pathogenic	0.776
BRCA1	P38398-1.2	K1160W	Pathogenic	0.823
BRCA1	P38398-1.2	K1160Y	Pathogenic	0.671
BRCA1	P38398-1.2	E1161A	Pathogenic	0.851
BRCA1	P38398-1.2	E1161C	Pathogenic	0.917
BRCA1	P38398-1.2	E1161D	Pathogenic	0.534
BRCA1	P38398-1.2	E1161F	Pathogenic	0.89
BRCA1	P38398-1.2	E1161G	Pathogenic	0.927
BRCA1	P38398-1.2	E1161H	Pathogenic	0.657
BRCA1	P38398-1.2	E1161I	Pathogenic	0.863
BRCA1	P38398-1.2	E1161K	Pathogenic	0.662
BRCA1	P38398-1.2	E1161L	Pathogenic	0.864
BRCA1	P38398-1.2	E1161M	Pathogenic	0.816
BRCA1	P38398-1.2	E1161N	Pathogenic	0.68
BRCA1	P38398-1.2	E1161P	Pathogenic	0.773
BRCA1	P38398-1.2	E1161Q	Neutral	0.46
BRCA1	P38398-1.2	E1161R	Pathogenic	0.79
BRCA1	P38398-1.2	E1161S	Pathogenic	0.778
BRCA1	P38398-1.2	E1161T	Pathogenic	0.763
BRCA1	P38398-1.2	E1161V	Pathogenic	0.777
BRCA1	P38398-1.2	E1161W	Pathogenic	0.937
BRCA1	P38398-1.2	E1161Y	Pathogenic	0.867
BRCA1	P38398-1.2	D1162A	Neutral	0.162
BRCA1	P38398-1.2	D1162C	Neutral	0.153
BRCA1	P38398-1.2	D1162E	Neutral	0.039
BRCA1	P38398-1.2	D1162F	Neutral	0.297
BRCA1	P38398-1.2	D1162G	Neutral	0.171
BRCA1	P38398-1.2	D1162H	Neutral	0.126
BRCA1	P38398-1.2	D1162I	Neutral	0.248
BRCA1	P38398-1.2	D1162K	Neutral	0.176
BRCA1	P38398-1.2	D1162L	Neutral	0.323
BRCA1	P38398-1.2	D1162M	Neutral	0.25
BRCA1	P38398-1.2	D1162N	Neutral	0.042
BRCA1	P38398-1.2	D1162P	Neutral	0.074
BRCA1	P38398-1.2	D1162Q	Neutral	0.084
BRCA1	P38398-1.2	D1162R	Neutral	0.29
BRCA1	P38398-1.2	D1162S	Neutral	0.076
BRCA1	P38398-1.2	D1162T	Neutral	0.076
BRCA1	P38398-1.2	D1162V	Neutral	0.18
BRCA1	P38398-1.2	D1162W	Pathogenic	0.528
BRCA1	P38398-1.2	D1162Y	Neutral	0.329
BRCA1	P38398-1.2	T1163A	Neutral	0.005
BRCA1	P38398-1.2	T1163C	Neutral	0.005
BRCA1	P38398-1.2	T1163D	Neutral	0.004
BRCA1	P38398-1.2	T1163E	Neutral	0.006
BRCA1	P38398-1.2	T1163F	Neutral	0.014
BRCA1	P38398-1.2	T1163G	Neutral	0.016
BRCA1	P38398-1.2	T1163H	Neutral	0.01
BRCA1	P38398-1.2	T1163I	Neutral	0.008
BRCA1	P38398-1.2	T1163K	Neutral	0.01
BRCA1	P38398-1.2	T1163L	Neutral	0.008
BRCA1	P38398-1.2	T1163M	Neutral	0.008
BRCA1	P38398-1.2	T1163N	Neutral	0.003
BRCA1	P38398-1.2	T1163P	Neutral	0.004
BRCA1	P38398-1.2	T1163Q	Neutral	0.007
BRCA1	P38398-1.2	T1163R	Neutral	0.014
BRCA1	P38398-1.2	T1163S	Neutral	0.003
BRCA1	P38398-1.2	T1163V	Neutral	0.004
BRCA1	P38398-1.2	T1163W	Neutral	0.026
BRCA1	P38398-1.2	T1163Y	Neutral	0.017
BRCA1	P38398-1.2	S1164A	Neutral	0.174
BRCA1	P38398-1.2	S1164C	Neutral	0.335
BRCA1	P38398-1.2	S1164D	Neutral	0.282
BRCA1	P38398-1.2	S1164E	Neutral	0.37
BRCA1	P38398-1.2	S1164F	Pathogenic	0.679
BRCA1	P38398-1.2	S1164G	Neutral	0.317
BRCA1	P38398-1.2	S1164H	Pathogenic	0.51
BRCA1	P38398-1.2	S1164I	Pathogenic	0.624
BRCA1	P38398-1.2	S1164K	Pathogenic	0.509
BRCA1	P38398-1.2	S1164L	Pathogenic	0.624
BRCA1	P38398-1.2	S1164M	Pathogenic	0.538
BRCA1	P38398-1.2	S1164N	Neutral	0.234
BRCA1	P38398-1.2	S1164P	Neutral	0.356
BRCA1	P38398-1.2	S1164Q	Neutral	0.398
BRCA1	P38398-1.2	S1164R	Pathogenic	0.666
BRCA1	P38398-1.2	S1164T	Neutral	0.223
BRCA1	P38398-1.2	S1164V	Pathogenic	0.523
BRCA1	P38398-1.2	S1164W	Pathogenic	0.849
BRCA1	P38398-1.2	S1164Y	Pathogenic	0.711
BRCA1	P38398-1.2	F1165A	Pathogenic	0.997
BRCA1	P38398-1.2	F1165C	Pathogenic	0.996
BRCA1	P38398-1.2	F1165D	Pathogenic	0.997
BRCA1	P38398-1.2	F1165E	Pathogenic	0.995
BRCA1	P38398-1.2	F1165G	Pathogenic	0.999
BRCA1	P38398-1.2	F1165H	Pathogenic	0.987
BRCA1	P38398-1.2	F1165I	Pathogenic	0.98
BRCA1	P38398-1.2	F1165K	Pathogenic	0.991
BRCA1	P38398-1.2	F1165L	Pathogenic	0.98
BRCA1	P38398-1.2	F1165M	Pathogenic	0.98
BRCA1	P38398-1.2	F1165N	Pathogenic	0.996
BRCA1	P38398-1.2	F1165P	Pathogenic	0.998
BRCA1	P38398-1.2	F1165Q	Pathogenic	0.994
BRCA1	P38398-1.2	F1165R	Pathogenic	0.993
BRCA1	P38398-1.2	F1165S	Pathogenic	0.997
BRCA1	P38398-1.2	F1165T	Pathogenic	0.995
BRCA1	P38398-1.2	F1165V	Pathogenic	0.991
BRCA1	P38398-1.2	F1165W	Pathogenic	0.98
BRCA1	P38398-1.2	F1165Y	Pathogenic	0.936
BRCA1	P38398-1.2	A1166C	Neutral	0.267
BRCA1	P38398-1.2	A1166D	Neutral	0.456
BRCA1	P38398-1.2	A1166E	Neutral	0.465
BRCA1	P38398-1.2	A1166F	Pathogenic	0.688
BRCA1	P38398-1.2	A1166G	Neutral	0.269
BRCA1	P38398-1.2	A1166H	Pathogenic	0.608
BRCA1	P38398-1.2	A1166I	Pathogenic	0.546
BRCA1	P38398-1.2	A1166K	Pathogenic	0.606
BRCA1	P38398-1.2	A1166L	Pathogenic	0.546
BRCA1	P38398-1.2	A1166M	Pathogenic	0.548
BRCA1	P38398-1.2	A1166N	Neutral	0.484
BRCA1	P38398-1.2	A1166P	Neutral	0.366
BRCA1	P38398-1.2	A1166Q	Neutral	0.495
BRCA1	P38398-1.2	A1166R	Pathogenic	0.673
BRCA1	P38398-1.2	A1166S	Neutral	0.16
BRCA1	P38398-1.2	A1166T	Neutral	0.301
BRCA1	P38398-1.2	A1166V	Neutral	0.356
BRCA1	P38398-1.2	A1166W	Pathogenic	0.854
BRCA1	P38398-1.2	A1166Y	Pathogenic	0.719
BRCA1	P38398-1.2	E1167A	Pathogenic	0.935
BRCA1	P38398-1.2	E1167C	Pathogenic	0.965
BRCA1	P38398-1.2	E1167D	Pathogenic	0.741
BRCA1	P38398-1.2	E1167F	Pathogenic	0.953
BRCA1	P38398-1.2	E1167G	Pathogenic	0.969
BRCA1	P38398-1.2	E1167H	Pathogenic	0.827
BRCA1	P38398-1.2	E1167I	Pathogenic	0.94
BRCA1	P38398-1.2	E1167K	Pathogenic	0.83
BRCA1	P38398-1.2	E1167L	Pathogenic	0.94
BRCA1	P38398-1.2	E1167M	Pathogenic	0.917
BRCA1	P38398-1.2	E1167N	Pathogenic	0.841
BRCA1	P38398-1.2	E1167P	Pathogenic	0.895
BRCA1	P38398-1.2	E1167Q	Pathogenic	0.68
BRCA1	P38398-1.2	E1167R	Pathogenic	0.904
BRCA1	P38398-1.2	E1167S	Pathogenic	0.897
BRCA1	P38398-1.2	E1167T	Pathogenic	0.889
BRCA1	P38398-1.2	E1167V	Pathogenic	0.897
BRCA1	P38398-1.2	E1167W	Pathogenic	0.974
BRCA1	P38398-1.2	E1167Y	Pathogenic	0.942
BRCA1	P38398-1.2	N1168A	Neutral	0.014
BRCA1	P38398-1.2	N1168C	Neutral	0.013
BRCA1	P38398-1.2	N1168D	Neutral	0.003
BRCA1	P38398-1.2	N1168E	Neutral	0.005
BRCA1	P38398-1.2	N1168F	Neutral	0.025
BRCA1	P38398-1.2	N1168G	Neutral	0.011
BRCA1	P38398-1.2	N1168H	Neutral	0.004
BRCA1	P38398-1.2	N1168I	Neutral	0.019
BRCA1	P38398-1.2	N1168K	Neutral	0.009
BRCA1	P38398-1.2	N1168L	Neutral	0.02
BRCA1	P38398-1.2	N1168M	Neutral	0.014
BRCA1	P38398-1.2	N1168P	Neutral	0.009
BRCA1	P38398-1.2	N1168Q	Neutral	0.006
BRCA1	P38398-1.2	N1168R	Neutral	0.012
BRCA1	P38398-1.2	N1168S	Neutral	0.004
BRCA1	P38398-1.2	N1168T	Neutral	0.004
BRCA1	P38398-1.2	N1168V	Neutral	0.013
BRCA1	P38398-1.2	N1168W	Neutral	0.063
BRCA1	P38398-1.2	N1168Y	Neutral	0.02
BRCA1	P38398-1.2	D1169A	Neutral	0.442
BRCA1	P38398-1.2	D1169C	Neutral	0.424
BRCA1	P38398-1.2	D1169E	Neutral	0.141
BRCA1	P38398-1.2	D1169F	Pathogenic	0.633
BRCA1	P38398-1.2	D1169G	Neutral	0.457
BRCA1	P38398-1.2	D1169H	Neutral	0.371
BRCA1	P38398-1.2	D1169I	Pathogenic	0.574
BRCA1	P38398-1.2	D1169K	Neutral	0.465
BRCA1	P38398-1.2	D1169L	Pathogenic	0.661
BRCA1	P38398-1.2	D1169M	Pathogenic	0.577
BRCA1	P38398-1.2	D1169N	Neutral	0.15
BRCA1	P38398-1.2	D1169P	Neutral	0.246
BRCA1	P38398-1.2	D1169Q	Neutral	0.274
BRCA1	P38398-1.2	D1169R	Pathogenic	0.626
BRCA1	P38398-1.2	D1169S	Neutral	0.252
BRCA1	P38398-1.2	D1169T	Neutral	0.252
BRCA1	P38398-1.2	D1169V	Neutral	0.472
BRCA1	P38398-1.2	D1169W	Pathogenic	0.821
BRCA1	P38398-1.2	D1169Y	Pathogenic	0.667
BRCA1	P38398-1.2	I1170A	Pathogenic	0.871
BRCA1	P38398-1.2	I1170C	Pathogenic	0.818
BRCA1	P38398-1.2	I1170D	Pathogenic	0.889
BRCA1	P38398-1.2	I1170E	Pathogenic	0.844
BRCA1	P38398-1.2	I1170F	Pathogenic	0.635
BRCA1	P38398-1.2	I1170G	Pathogenic	0.968
BRCA1	P38398-1.2	I1170H	Pathogenic	0.818
BRCA1	P38398-1.2	I1170K	Pathogenic	0.831
BRCA1	P38398-1.2	I1170L	Neutral	0.396
BRCA1	P38398-1.2	I1170M	Neutral	0.484
BRCA1	P38398-1.2	I1170N	Pathogenic	0.878
BRCA1	P38398-1.2	I1170P	Pathogenic	0.894
BRCA1	P38398-1.2	I1170Q	Pathogenic	0.83
BRCA1	P38398-1.2	I1170R	Pathogenic	0.868
BRCA1	P38398-1.2	I1170S	Pathogenic	0.894
BRCA1	P38398-1.2	I1170T	Pathogenic	0.791
BRCA1	P38398-1.2	I1170V	Neutral	0.408
BRCA1	P38398-1.2	I1170W	Pathogenic	0.905
BRCA1	P38398-1.2	I1170Y	Pathogenic	0.738
BRCA1	P38398-1.2	K1171A	Pathogenic	0.767
BRCA1	P38398-1.2	K1171C	Pathogenic	0.815
BRCA1	P38398-1.2	K1171D	Pathogenic	0.663
BRCA1	P38398-1.2	K1171E	Neutral	0.388
BRCA1	P38398-1.2	K1171F	Pathogenic	0.593
BRCA1	P38398-1.2	K1171G	Pathogenic	0.879
BRCA1	P38398-1.2	K1171H	Pathogenic	0.515
BRCA1	P38398-1.2	K1171I	Pathogenic	0.651
BRCA1	P38398-1.2	K1171L	Pathogenic	0.565
BRCA1	P38398-1.2	K1171M	Neutral	0.476
BRCA1	P38398-1.2	K1171N	Pathogenic	0.549
BRCA1	P38398-1.2	K1171P	Pathogenic	0.662
BRCA1	P38398-1.2	K1171Q	Neutral	0.361
BRCA1	P38398-1.2	K1171R	Neutral	0.25
BRCA1	P38398-1.2	K1171S	Pathogenic	0.668
BRCA1	P38398-1.2	K1171T	Pathogenic	0.648
BRCA1	P38398-1.2	K1171V	Pathogenic	0.666
BRCA1	P38398-1.2	K1171W	Pathogenic	0.729
BRCA1	P38398-1.2	K1171Y	Pathogenic	0.541
BRCA1	P38398-1.2	E1172A	Pathogenic	0.988
BRCA1	P38398-1.2	E1172C	Pathogenic	0.994
BRCA1	P38398-1.2	E1172D	Pathogenic	0.944
BRCA1	P38398-1.2	E1172F	Pathogenic	0.992
BRCA1	P38398-1.2	E1172G	Pathogenic	0.995
BRCA1	P38398-1.2	E1172H	Pathogenic	0.966
BRCA1	P38398-1.2	E1172I	Pathogenic	0.989
BRCA1	P38398-1.2	E1172K	Pathogenic	0.967
BRCA1	P38398-1.2	E1172L	Pathogenic	0.989
BRCA1	P38398-1.2	E1172M	Pathogenic	0.985
BRCA1	P38398-1.2	E1172N	Pathogenic	0.969
BRCA1	P38398-1.2	E1172P	Pathogenic	0.981
BRCA1	P38398-1.2	E1172Q	Pathogenic	0.926
BRCA1	P38398-1.2	E1172R	Pathogenic	0.982
BRCA1	P38398-1.2	E1172S	Pathogenic	0.981
BRCA1	P38398-1.2	E1172T	Pathogenic	0.979
BRCA1	P38398-1.2	E1172V	Pathogenic	0.981
BRCA1	P38398-1.2	E1172W	Pathogenic	0.995
BRCA1	P38398-1.2	E1172Y	Pathogenic	0.99
BRCA1	P38398-1.2	S1173A	Neutral	0.005
BRCA1	P38398-1.2	S1173C	Neutral	0.012
BRCA1	P38398-1.2	S1173D	Neutral	0.01
BRCA1	P38398-1.2	S1173E	Neutral	0.014
BRCA1	P38398-1.2	S1173F	Neutral	0.05
BRCA1	P38398-1.2	S1173G	Neutral	0.012
BRCA1	P38398-1.2	S1173H	Neutral	0.025
BRCA1	P38398-1.2	S1173I	Neutral	0.04
BRCA1	P38398-1.2	S1173K	Neutral	0.025
BRCA1	P38398-1.2	S1173L	Neutral	0.04
BRCA1	P38398-1.2	S1173M	Neutral	0.028
BRCA1	P38398-1.2	S1173N	Neutral	0.008
BRCA1	P38398-1.2	S1173P	Neutral	0.014
BRCA1	P38398-1.2	S1173Q	Neutral	0.016
BRCA1	P38398-1.2	S1173R	Neutral	0.048
BRCA1	P38398-1.2	S1173T	Neutral	0.007
BRCA1	P38398-1.2	S1173V	Neutral	0.027
BRCA1	P38398-1.2	S1173W	Neutral	0.123
BRCA1	P38398-1.2	S1173Y	Neutral	0.058
BRCA1	P38398-1.2	S1174A	Pathogenic	0.952
BRCA1	P38398-1.2	S1174C	Pathogenic	0.979
BRCA1	P38398-1.2	S1174D	Pathogenic	0.974
BRCA1	P38398-1.2	S1174E	Pathogenic	0.982
BRCA1	P38398-1.2	S1174F	Pathogenic	0.995
BRCA1	P38398-1.2	S1174G	Pathogenic	0.978
BRCA1	P38398-1.2	S1174H	Pathogenic	0.99
BRCA1	P38398-1.2	S1174I	Pathogenic	0.994
BRCA1	P38398-1.2	S1174K	Pathogenic	0.99
BRCA1	P38398-1.2	S1174L	Pathogenic	0.994
BRCA1	P38398-1.2	S1174M	Pathogenic	0.991
BRCA1	P38398-1.2	S1174N	Pathogenic	0.966
BRCA1	P38398-1.2	S1174P	Pathogenic	0.981
BRCA1	P38398-1.2	S1174Q	Pathogenic	0.984
BRCA1	P38398-1.2	S1174R	Pathogenic	0.995
BRCA1	P38398-1.2	S1174T	Pathogenic	0.964
BRCA1	P38398-1.2	S1174V	Pathogenic	0.99
BRCA1	P38398-1.2	S1174W	Pathogenic	0.998
BRCA1	P38398-1.2	S1174Y	Pathogenic	0.996
BRCA1	P38398-1.2	A1175C	Pathogenic	0.969
BRCA1	P38398-1.2	A1175D	Pathogenic	0.986
BRCA1	P38398-1.2	A1175E	Pathogenic	0.987
BRCA1	P38398-1.2	A1175F	Pathogenic	0.995
BRCA1	P38398-1.2	A1175G	Pathogenic	0.969
BRCA1	P38398-1.2	A1175H	Pathogenic	0.992
BRCA1	P38398-1.2	A1175I	Pathogenic	0.99
BRCA1	P38398-1.2	A1175K	Pathogenic	0.992
BRCA1	P38398-1.2	A1175L	Pathogenic	0.99
BRCA1	P38398-1.2	A1175M	Pathogenic	0.99
BRCA1	P38398-1.2	A1175N	Pathogenic	0.988
BRCA1	P38398-1.2	A1175P	Pathogenic	0.98
BRCA1	P38398-1.2	A1175Q	Pathogenic	0.988
BRCA1	P38398-1.2	A1175R	Pathogenic	0.994
BRCA1	P38398-1.2	A1175S	Pathogenic	0.942
BRCA1	P38398-1.2	A1175T	Pathogenic	0.973
BRCA1	P38398-1.2	A1175V	Pathogenic	0.979
BRCA1	P38398-1.2	A1175W	Pathogenic	0.998
BRCA1	P38398-1.2	A1175Y	Pathogenic	0.995
BRCA1	P38398-1.2	V1176A	Pathogenic	0.972
BRCA1	P38398-1.2	V1176C	Pathogenic	0.971
BRCA1	P38398-1.2	V1176D	Pathogenic	0.984
BRCA1	P38398-1.2	V1176E	Pathogenic	0.971
BRCA1	P38398-1.2	V1176F	Pathogenic	0.977
BRCA1	P38398-1.2	V1176G	Pathogenic	0.994
BRCA1	P38398-1.2	V1176H	Pathogenic	0.984
BRCA1	P38398-1.2	V1176I	Pathogenic	0.886
BRCA1	P38398-1.2	V1176K	Pathogenic	0.984
BRCA1	P38398-1.2	V1176L	Pathogenic	0.942
BRCA1	P38398-1.2	V1176M	Pathogenic	0.942
BRCA1	P38398-1.2	V1176N	Pathogenic	0.982
BRCA1	P38398-1.2	V1176P	Pathogenic	0.978
BRCA1	P38398-1.2	V1176Q	Pathogenic	0.974
BRCA1	P38398-1.2	V1176R	Pathogenic	0.991
BRCA1	P38398-1.2	V1176S	Pathogenic	0.985
BRCA1	P38398-1.2	V1176T	Pathogenic	0.952
BRCA1	P38398-1.2	V1176W	Pathogenic	0.994
BRCA1	P38398-1.2	V1176Y	Pathogenic	0.98
BRCA1	P38398-1.2	F1177A	Pathogenic	0.998
BRCA1	P38398-1.2	F1177C	Pathogenic	0.998
BRCA1	P38398-1.2	F1177D	Pathogenic	0.998
BRCA1	P38398-1.2	F1177E	Pathogenic	0.997
BRCA1	P38398-1.2	F1177G	Pathogenic	0.999
BRCA1	P38398-1.2	F1177H	Pathogenic	0.993
BRCA1	P38398-1.2	F1177I	Pathogenic	0.988
BRCA1	P38398-1.2	F1177K	Pathogenic	0.995
BRCA1	P38398-1.2	F1177L	Pathogenic	0.988
BRCA1	P38398-1.2	F1177M	Pathogenic	0.988
BRCA1	P38398-1.2	F1177N	Pathogenic	0.998
BRCA1	P38398-1.2	F1177P	Pathogenic	0.999
BRCA1	P38398-1.2	F1177Q	Pathogenic	0.997
BRCA1	P38398-1.2	F1177R	Pathogenic	0.996
BRCA1	P38398-1.2	F1177S	Pathogenic	0.998
BRCA1	P38398-1.2	F1177T	Pathogenic	0.997
BRCA1	P38398-1.2	F1177V	Pathogenic	0.995
BRCA1	P38398-1.2	F1177W	Pathogenic	0.988
BRCA1	P38398-1.2	F1177Y	Pathogenic	0.962
BRCA1	P38398-1.2	S1178A	Neutral	0.188
BRCA1	P38398-1.2	S1178C	Neutral	0.357
BRCA1	P38398-1.2	S1178D	Neutral	0.302
BRCA1	P38398-1.2	S1178E	Neutral	0.393
BRCA1	P38398-1.2	S1178F	Pathogenic	0.7
BRCA1	P38398-1.2	S1178G	Neutral	0.339
BRCA1	P38398-1.2	S1178H	Pathogenic	0.534
BRCA1	P38398-1.2	S1178I	Pathogenic	0.646
BRCA1	P38398-1.2	S1178K	Pathogenic	0.534
BRCA1	P38398-1.2	S1178L	Pathogenic	0.647
BRCA1	P38398-1.2	S1178M	Pathogenic	0.562
BRCA1	P38398-1.2	S1178N	Neutral	0.252
BRCA1	P38398-1.2	S1178P	Neutral	0.378
BRCA1	P38398-1.2	S1178Q	Neutral	0.422
BRCA1	P38398-1.2	S1178R	Pathogenic	0.687
BRCA1	P38398-1.2	S1178T	Neutral	0.241
BRCA1	P38398-1.2	S1178V	Pathogenic	0.548
BRCA1	P38398-1.2	S1178W	Pathogenic	0.861
BRCA1	P38398-1.2	S1178Y	Pathogenic	0.73
BRCA1	P38398-1.2	K1179A	Pathogenic	0.791
BRCA1	P38398-1.2	K1179C	Pathogenic	0.836
BRCA1	P38398-1.2	K1179D	Pathogenic	0.694
BRCA1	P38398-1.2	K1179E	Neutral	0.423
BRCA1	P38398-1.2	K1179F	Pathogenic	0.628
BRCA1	P38398-1.2	K1179G	Pathogenic	0.893
BRCA1	P38398-1.2	K1179H	Pathogenic	0.551
BRCA1	P38398-1.2	K1179I	Pathogenic	0.683
BRCA1	P38398-1.2	K1179L	Pathogenic	0.6
BRCA1	P38398-1.2	K1179M	Pathogenic	0.512
BRCA1	P38398-1.2	K1179N	Pathogenic	0.585
BRCA1	P38398-1.2	K1179P	Pathogenic	0.693
BRCA1	P38398-1.2	K1179Q	Neutral	0.394
BRCA1	P38398-1.2	K1179R	Neutral	0.278
BRCA1	P38398-1.2	K1179S	Pathogenic	0.699
BRCA1	P38398-1.2	K1179T	Pathogenic	0.681
BRCA1	P38398-1.2	K1179V	Pathogenic	0.698
BRCA1	P38398-1.2	K1179W	Pathogenic	0.757
BRCA1	P38398-1.2	K1179Y	Pathogenic	0.576
BRCA1	P38398-1.2	S1180A	Neutral	0.041
BRCA1	P38398-1.2	S1180C	Neutral	0.093
BRCA1	P38398-1.2	S1180D	Neutral	0.074
BRCA1	P38398-1.2	S1180E	Neutral	0.107
BRCA1	P38398-1.2	S1180F	Neutral	0.302
BRCA1	P38398-1.2	S1180G	Neutral	0.087
BRCA1	P38398-1.2	S1180H	Neutral	0.176
BRCA1	P38398-1.2	S1180I	Neutral	0.253
BRCA1	P38398-1.2	S1180K	Neutral	0.175
BRCA1	P38398-1.2	S1180L	Neutral	0.254
BRCA1	P38398-1.2	S1180M	Neutral	0.192
BRCA1	P38398-1.2	S1180N	Neutral	0.059
BRCA1	P38398-1.2	S1180P	Neutral	0.102
BRCA1	P38398-1.2	S1180Q	Neutral	0.119
BRCA1	P38398-1.2	S1180R	Neutral	0.29
BRCA1	P38398-1.2	S1180T	Neutral	0.056
BRCA1	P38398-1.2	S1180V	Neutral	0.184
BRCA1	P38398-1.2	S1180W	Pathogenic	0.535
BRCA1	P38398-1.2	S1180Y	Neutral	0.335
BRCA1	P38398-1.2	V1181A	Neutral	0.34
BRCA1	P38398-1.2	V1181C	Neutral	0.33
BRCA1	P38398-1.2	V1181D	Neutral	0.468
BRCA1	P38398-1.2	V1181E	Neutral	0.329
BRCA1	P38398-1.2	V1181F	Neutral	0.384
BRCA1	P38398-1.2	V1181G	Pathogenic	0.699
BRCA1	P38398-1.2	V1181H	Neutral	0.467
BRCA1	P38398-1.2	V1181I	Neutral	0.102
BRCA1	P38398-1.2	V1181K	Neutral	0.465
BRCA1	P38398-1.2	V1181L	Neutral	0.191
BRCA1	P38398-1.2	V1181M	Neutral	0.192
BRCA1	P38398-1.2	V1181N	Neutral	0.442
BRCA1	P38398-1.2	V1181P	Neutral	0.392
BRCA1	P38398-1.2	V1181Q	Neutral	0.356
BRCA1	P38398-1.2	V1181R	Pathogenic	0.625
BRCA1	P38398-1.2	V1181S	Neutral	0.481
BRCA1	P38398-1.2	V1181T	Neutral	0.224
BRCA1	P38398-1.2	V1181W	Pathogenic	0.704
BRCA1	P38398-1.2	V1181Y	Neutral	0.418
BRCA1	P38398-1.2	Q1182A	Pathogenic	0.754
BRCA1	P38398-1.2	Q1182C	Pathogenic	0.805
BRCA1	P38398-1.2	Q1182D	Pathogenic	0.556
BRCA1	P38398-1.2	Q1182E	Neutral	0.289
BRCA1	P38398-1.2	Q1182F	Pathogenic	0.776
BRCA1	P38398-1.2	Q1182G	Pathogenic	0.872
BRCA1	P38398-1.2	Q1182H	Neutral	0.452
BRCA1	P38398-1.2	Q1182I	Pathogenic	0.731
BRCA1	P38398-1.2	Q1182K	Neutral	0.453
BRCA1	P38398-1.2	Q1182L	Pathogenic	0.654
BRCA1	P38398-1.2	Q1182M	Neutral	0.48
BRCA1	P38398-1.2	Q1182N	Pathogenic	0.529
BRCA1	P38398-1.2	Q1182P	Pathogenic	0.646
BRCA1	P38398-1.2	Q1182R	Pathogenic	0.525
BRCA1	P38398-1.2	Q1182S	Pathogenic	0.653
BRCA1	P38398-1.2	Q1182T	Pathogenic	0.633
BRCA1	P38398-1.2	Q1182V	Pathogenic	0.651
BRCA1	P38398-1.2	Q1182W	Pathogenic	0.817
BRCA1	P38398-1.2	Q1182Y	Pathogenic	0.661
BRCA1	P38398-1.2	K1183A	Neutral	0.301
BRCA1	P38398-1.2	K1183C	Neutral	0.366
BRCA1	P38398-1.2	K1183D	Neutral	0.205
BRCA1	P38398-1.2	K1183E	Neutral	0.077
BRCA1	P38398-1.2	K1183F	Neutral	0.161
BRCA1	P38398-1.2	K1183G	Neutral	0.488
BRCA1	P38398-1.2	K1183H	Neutral	0.122
BRCA1	P38398-1.2	K1183I	Neutral	0.197
BRCA1	P38398-1.2	K1183L	Neutral	0.146
BRCA1	P38398-1.2	K1183M	Neutral	0.107
BRCA1	P38398-1.2	K1183N	Neutral	0.138
BRCA1	P38398-1.2	K1183P	Neutral	0.204
BRCA1	P38398-1.2	K1183Q	Neutral	0.069
BRCA1	P38398-1.2	K1183R	Neutral	0.042
BRCA1	P38398-1.2	K1183S	Neutral	0.209
BRCA1	P38398-1.2	K1183T	Neutral	0.195
BRCA1	P38398-1.2	K1183V	Neutral	0.208
BRCA1	P38398-1.2	K1183W	Neutral	0.261
BRCA1	P38398-1.2	K1183Y	Neutral	0.134
BRCA1	P38398-1.2	G1184A	Neutral	0.05
BRCA1	P38398-1.2	G1184C	Neutral	0.192
BRCA1	P38398-1.2	G1184D	Neutral	0.114
BRCA1	P38398-1.2	G1184E	Neutral	0.217
BRCA1	P38398-1.2	G1184F	Neutral	0.41
BRCA1	P38398-1.2	G1184H	Neutral	0.255
BRCA1	P38398-1.2	G1184I	Neutral	0.439
BRCA1	P38398-1.2	G1184K	Neutral	0.329
BRCA1	P38398-1.2	G1184L	Neutral	0.44
BRCA1	P38398-1.2	G1184M	Neutral	0.355
BRCA1	P38398-1.2	G1184N	Neutral	0.091
BRCA1	P38398-1.2	G1184P	Neutral	0.154
BRCA1	P38398-1.2	G1184Q	Neutral	0.238
BRCA1	P38398-1.2	G1184R	Neutral	0.396
BRCA1	P38398-1.2	G1184S	Neutral	0.057
BRCA1	P38398-1.2	G1184T	Neutral	0.164
BRCA1	P38398-1.2	G1184V	Neutral	0.265
BRCA1	P38398-1.2	G1184W	Neutral	0.472
BRCA1	P38398-1.2	G1184Y	Neutral	0.447
BRCA1	P38398-1.2	E1185A	Neutral	0.411
BRCA1	P38398-1.2	E1185C	Pathogenic	0.574
BRCA1	P38398-1.2	E1185D	Neutral	0.122
BRCA1	P38398-1.2	E1185F	Neutral	0.496
BRCA1	P38398-1.2	E1185G	Pathogenic	0.606
BRCA1	P38398-1.2	E1185H	Neutral	0.189
BRCA1	P38398-1.2	E1185I	Neutral	0.435
BRCA1	P38398-1.2	E1185K	Neutral	0.193
BRCA1	P38398-1.2	E1185L	Neutral	0.436
BRCA1	P38398-1.2	E1185M	Neutral	0.351
BRCA1	P38398-1.2	E1185N	Neutral	0.206
BRCA1	P38398-1.2	E1185P	Neutral	0.293
BRCA1	P38398-1.2	E1185Q	Neutral	0.094
BRCA1	P38398-1.2	E1185R	Neutral	0.314
BRCA1	P38398-1.2	E1185S	Neutral	0.299
BRCA1	P38398-1.2	E1185T	Neutral	0.282
BRCA1	P38398-1.2	E1185V	Neutral	0.298
BRCA1	P38398-1.2	E1185W	Pathogenic	0.645
BRCA1	P38398-1.2	E1185Y	Neutral	0.443
BRCA1	P38398-1.2	L1186A	Neutral	0.1
BRCA1	P38398-1.2	L1186C	Neutral	0.069
BRCA1	P38398-1.2	L1186D	Neutral	0.16
BRCA1	P38398-1.2	L1186E	Neutral	0.082
BRCA1	P38398-1.2	L1186F	Neutral	0.028
BRCA1	P38398-1.2	L1186G	Neutral	0.335
BRCA1	P38398-1.2	L1186H	Neutral	0.069
BRCA1	P38398-1.2	L1186I	Neutral	0.011
BRCA1	P38398-1.2	L1186K	Neutral	0.053
BRCA1	P38398-1.2	L1186M	Neutral	0.011
BRCA1	P38398-1.2	L1186N	Neutral	0.106
BRCA1	P38398-1.2	L1186P	Neutral	0.122
BRCA1	P38398-1.2	L1186Q	Neutral	0.053
BRCA1	P38398-1.2	L1186R	Neutral	0.07
BRCA1	P38398-1.2	L1186S	Neutral	0.122
BRCA1	P38398-1.2	L1186T	Neutral	0.059
BRCA1	P38398-1.2	L1186V	Neutral	0.023
BRCA1	P38398-1.2	L1186W	Neutral	0.098
BRCA1	P38398-1.2	L1186Y	Neutral	0.044
BRCA1	P38398-1.2	S1187A	Neutral	0.019
BRCA1	P38398-1.2	S1187C	Neutral	0.044
BRCA1	P38398-1.2	S1187D	Neutral	0.035
BRCA1	P38398-1.2	S1187E	Neutral	0.051
BRCA1	P38398-1.2	S1187F	Neutral	0.163
BRCA1	P38398-1.2	S1187G	Neutral	0.041
BRCA1	P38398-1.2	S1187H	Neutral	0.088
BRCA1	P38398-1.2	S1187I	Neutral	0.133
BRCA1	P38398-1.2	S1187K	Neutral	0.087
BRCA1	P38398-1.2	S1187L	Neutral	0.133
BRCA1	P38398-1.2	S1187M	Neutral	0.097
BRCA1	P38398-1.2	S1187N	Neutral	0.027
BRCA1	P38398-1.2	S1187P	Neutral	0.048
BRCA1	P38398-1.2	S1187Q	Neutral	0.058
BRCA1	P38398-1.2	S1187R	Neutral	0.155
BRCA1	P38398-1.2	S1187T	Neutral	0.026
BRCA1	P38398-1.2	S1187V	Neutral	0.092
BRCA1	P38398-1.2	S1187W	Neutral	0.341
BRCA1	P38398-1.2	S1187Y	Neutral	0.185
BRCA1	P38398-1.2	R1188A	Pathogenic	0.963
BRCA1	P38398-1.2	R1188C	Pathogenic	0.972
BRCA1	P38398-1.2	R1188D	Pathogenic	0.958
BRCA1	P38398-1.2	R1188E	Pathogenic	0.879
BRCA1	P38398-1.2	R1188F	Pathogenic	0.921
BRCA1	P38398-1.2	R1188G	Pathogenic	0.983
BRCA1	P38398-1.2	R1188H	Pathogenic	0.855
BRCA1	P38398-1.2	R1188I	Pathogenic	0.937
BRCA1	P38398-1.2	R1188K	Pathogenic	0.665
BRCA1	P38398-1.2	R1188L	Pathogenic	0.912
BRCA1	P38398-1.2	R1188M	Pathogenic	0.879
BRCA1	P38398-1.2	R1188N	Pathogenic	0.907
BRCA1	P38398-1.2	R1188P	Pathogenic	0.957
BRCA1	P38398-1.2	R1188Q	Pathogenic	0.818
BRCA1	P38398-1.2	R1188S	Pathogenic	0.958
BRCA1	P38398-1.2	R1188T	Pathogenic	0.936
BRCA1	P38398-1.2	R1188V	Pathogenic	0.958
BRCA1	P38398-1.2	R1188W	Pathogenic	0.923
BRCA1	P38398-1.2	R1188Y	Pathogenic	0.878
BRCA1	P38398-1.2	S1189A	Pathogenic	0.628
BRCA1	P38398-1.2	S1189C	Pathogenic	0.801
BRCA1	P38398-1.2	S1189D	Pathogenic	0.759
BRCA1	P38398-1.2	S1189E	Pathogenic	0.825
BRCA1	P38398-1.2	S1189F	Pathogenic	0.944
BRCA1	P38398-1.2	S1189G	Pathogenic	0.788
BRCA1	P38398-1.2	S1189H	Pathogenic	0.893
BRCA1	P38398-1.2	S1189I	Pathogenic	0.93
BRCA1	P38398-1.2	S1189K	Pathogenic	0.893
BRCA1	P38398-1.2	S1189L	Pathogenic	0.93
BRCA1	P38398-1.2	S1189M	Pathogenic	0.903
BRCA1	P38398-1.2	S1189N	Pathogenic	0.71
BRCA1	P38398-1.2	S1189P	Pathogenic	0.816
BRCA1	P38398-1.2	S1189Q	Pathogenic	0.841
BRCA1	P38398-1.2	S1189R	Pathogenic	0.941
BRCA1	P38398-1.2	S1189T	Pathogenic	0.698
BRCA1	P38398-1.2	S1189V	Pathogenic	0.898
BRCA1	P38398-1.2	S1189W	Pathogenic	0.978
BRCA1	P38398-1.2	S1189Y	Pathogenic	0.952
BRCA1	P38398-1.2	P1190A	Pathogenic	0.899
BRCA1	P38398-1.2	P1190C	Pathogenic	0.924
BRCA1	P38398-1.2	P1190D	Pathogenic	0.842
BRCA1	P38398-1.2	P1190E	Pathogenic	0.888
BRCA1	P38398-1.2	P1190F	Pathogenic	0.977
BRCA1	P38398-1.2	P1190G	Pathogenic	0.951
BRCA1	P38398-1.2	P1190H	Pathogenic	0.934
BRCA1	P38398-1.2	P1190I	Pathogenic	0.959
BRCA1	P38398-1.2	P1190K	Pathogenic	0.934
BRCA1	P38398-1.2	P1190L	Pathogenic	0.959
BRCA1	P38398-1.2	P1190M	Pathogenic	0.942
BRCA1	P38398-1.2	P1190N	Pathogenic	0.896
BRCA1	P38398-1.2	P1190Q	Pathogenic	0.9
BRCA1	P38398-1.2	P1190R	Pathogenic	0.964
BRCA1	P38398-1.2	P1190S	Pathogenic	0.885
BRCA1	P38398-1.2	P1190T	Pathogenic	0.85
BRCA1	P38398-1.2	P1190V	Pathogenic	0.914
BRCA1	P38398-1.2	P1190W	Pathogenic	0.987
BRCA1	P38398-1.2	P1190Y	Pathogenic	0.972
BRCA1	P38398-1.2	S1191A	Pathogenic	0.596
BRCA1	P38398-1.2	S1191C	Pathogenic	0.779
BRCA1	P38398-1.2	S1191D	Pathogenic	0.734
BRCA1	P38398-1.2	S1191E	Pathogenic	0.805
BRCA1	P38398-1.2	S1191F	Pathogenic	0.937
BRCA1	P38398-1.2	S1191G	Pathogenic	0.765
BRCA1	P38398-1.2	S1191H	Pathogenic	0.88
BRCA1	P38398-1.2	S1191I	Pathogenic	0.921
BRCA1	P38398-1.2	S1191K	Pathogenic	0.879
BRCA1	P38398-1.2	S1191L	Pathogenic	0.921
BRCA1	P38398-1.2	S1191M	Pathogenic	0.891
BRCA1	P38398-1.2	S1191N	Pathogenic	0.682
BRCA1	P38398-1.2	S1191P	Pathogenic	0.795
BRCA1	P38398-1.2	S1191Q	Pathogenic	0.823
BRCA1	P38398-1.2	S1191R	Pathogenic	0.933
BRCA1	P38398-1.2	S1191T	Pathogenic	0.669
BRCA1	P38398-1.2	S1191V	Pathogenic	0.885
BRCA1	P38398-1.2	S1191W	Pathogenic	0.975
BRCA1	P38398-1.2	S1191Y	Pathogenic	0.945
BRCA1	P38398-1.2	P1192A	Pathogenic	0.971
BRCA1	P38398-1.2	P1192C	Pathogenic	0.978
BRCA1	P38398-1.2	P1192D	Pathogenic	0.952
BRCA1	P38398-1.2	P1192E	Pathogenic	0.967
BRCA1	P38398-1.2	P1192F	Pathogenic	0.994
BRCA1	P38398-1.2	P1192G	Pathogenic	0.986
BRCA1	P38398-1.2	P1192H	Pathogenic	0.981
BRCA1	P38398-1.2	P1192I	Pathogenic	0.989
BRCA1	P38398-1.2	P1192K	Pathogenic	0.981
BRCA1	P38398-1.2	P1192L	Pathogenic	0.989
BRCA1	P38398-1.2	P1192M	Pathogenic	0.984
BRCA1	P38398-1.2	P1192N	Pathogenic	0.97
BRCA1	P38398-1.2	P1192Q	Pathogenic	0.971
BRCA1	P38398-1.2	P1192R	Pathogenic	0.99
BRCA1	P38398-1.2	P1192S	Pathogenic	0.966
BRCA1	P38398-1.2	P1192T	Pathogenic	0.955
BRCA1	P38398-1.2	P1192V	Pathogenic	0.975
BRCA1	P38398-1.2	P1192W	Pathogenic	0.997
BRCA1	P38398-1.2	P1192Y	Pathogenic	0.992
BRCA1	P38398-1.2	F1193A	Neutral	0.396
BRCA1	P38398-1.2	F1193C	Neutral	0.303
BRCA1	P38398-1.2	F1193D	Neutral	0.352
BRCA1	P38398-1.2	F1193E	Neutral	0.267
BRCA1	P38398-1.2	F1193G	Pathogenic	0.589
BRCA1	P38398-1.2	F1193H	Neutral	0.128
BRCA1	P38398-1.2	F1193I	Neutral	0.084
BRCA1	P38398-1.2	F1193K	Neutral	0.169
BRCA1	P38398-1.2	F1193L	Neutral	0.084
BRCA1	P38398-1.2	F1193M	Neutral	0.083
BRCA1	P38398-1.2	F1193N	Neutral	0.327
BRCA1	P38398-1.2	F1193P	Neutral	0.451
BRCA1	P38398-1.2	F1193Q	Neutral	0.247
BRCA1	P38398-1.2	F1193R	Neutral	0.213
BRCA1	P38398-1.2	F1193S	Neutral	0.363
BRCA1	P38398-1.2	F1193T	Neutral	0.269
BRCA1	P38398-1.2	F1193V	Neutral	0.166
BRCA1	P38398-1.2	F1193W	Neutral	0.084
BRCA1	P38398-1.2	F1193Y	Neutral	0.026
BRCA1	P38398-1.2	T1194A	Neutral	0.003
BRCA1	P38398-1.2	T1194C	Neutral	0.003
BRCA1	P38398-1.2	T1194D	Neutral	0.003
BRCA1	P38398-1.2	T1194E	Neutral	0.004
BRCA1	P38398-1.2	T1194F	Neutral	0.01
BRCA1	P38398-1.2	T1194G	Neutral	0.011
BRCA1	P38398-1.2	T1194H	Neutral	0.007
BRCA1	P38398-1.2	T1194I	Neutral	0.005
BRCA1	P38398-1.2	T1194K	Neutral	0.007
BRCA1	P38398-1.2	T1194L	Neutral	0.005
BRCA1	P38398-1.2	T1194M	Neutral	0.005
BRCA1	P38398-1.2	T1194N	Neutral	0.002
BRCA1	P38398-1.2	T1194P	Neutral	0.003
BRCA1	P38398-1.2	T1194Q	Neutral	0.004
BRCA1	P38398-1.2	T1194R	Neutral	0.009
BRCA1	P38398-1.2	T1194S	Neutral	0.002
BRCA1	P38398-1.2	T1194V	Neutral	0.003
BRCA1	P38398-1.2	T1194W	Neutral	0.018
BRCA1	P38398-1.2	T1194Y	Neutral	0.012
BRCA1	P38398-1.2	H1195A	Pathogenic	0.526
BRCA1	P38398-1.2	H1195C	Pathogenic	0.508
BRCA1	P38398-1.2	H1195D	Neutral	0.308
BRCA1	P38398-1.2	H1195E	Neutral	0.172
BRCA1	P38398-1.2	H1195F	Neutral	0.26
BRCA1	P38398-1.2	H1195G	Pathogenic	0.629
BRCA1	P38398-1.2	H1195I	Neutral	0.363
BRCA1	P38398-1.2	H1195K	Neutral	0.262
BRCA1	P38398-1.2	H1195L	Neutral	0.364
BRCA1	P38398-1.2	H1195M	Neutral	0.286
BRCA1	P38398-1.2	H1195N	Neutral	0.162
BRCA1	P38398-1.2	H1195P	Neutral	0.398
BRCA1	P38398-1.2	H1195Q	Neutral	0.158
BRCA1	P38398-1.2	H1195R	Neutral	0.248
BRCA1	P38398-1.2	H1195S	Neutral	0.403
BRCA1	P38398-1.2	H1195T	Neutral	0.384
BRCA1	P38398-1.2	H1195V	Neutral	0.403
BRCA1	P38398-1.2	H1195W	Neutral	0.483
BRCA1	P38398-1.2	H1195Y	Neutral	0.121
BRCA1	P38398-1.2	T1196A	Neutral	0.052
BRCA1	P38398-1.2	T1196C	Neutral	0.048
BRCA1	P38398-1.2	T1196D	Neutral	0.043
BRCA1	P38398-1.2	T1196E	Neutral	0.058
BRCA1	P38398-1.2	T1196F	Neutral	0.135
BRCA1	P38398-1.2	T1196G	Neutral	0.146
BRCA1	P38398-1.2	T1196H	Neutral	0.099
BRCA1	P38398-1.2	T1196I	Neutral	0.078
BRCA1	P38398-1.2	T1196K	Neutral	0.099
BRCA1	P38398-1.2	T1196L	Neutral	0.079
BRCA1	P38398-1.2	T1196M	Neutral	0.079
BRCA1	P38398-1.2	T1196N	Neutral	0.031
BRCA1	P38398-1.2	T1196P	Neutral	0.045
BRCA1	P38398-1.2	T1196Q	Neutral	0.065
BRCA1	P38398-1.2	T1196R	Neutral	0.127
BRCA1	P38398-1.2	T1196S	Neutral	0.032
BRCA1	P38398-1.2	T1196V	Neutral	0.038
BRCA1	P38398-1.2	T1196W	Neutral	0.224
BRCA1	P38398-1.2	T1196Y	Neutral	0.154
BRCA1	P38398-1.2	H1197A	Neutral	0.006
BRCA1	P38398-1.2	H1197C	Neutral	0.005
BRCA1	P38398-1.2	H1197D	Neutral	0.002
BRCA1	P38398-1.2	H1197E	Neutral	0.001
BRCA1	P38398-1.2	H1197F	Neutral	0.002
BRCA1	P38398-1.2	H1197G	Neutral	0.009
BRCA1	P38398-1.2	H1197I	Neutral	0.003
BRCA1	P38398-1.2	H1197K	Neutral	0.002
BRCA1	P38398-1.2	H1197L	Neutral	0.003
BRCA1	P38398-1.2	H1197M	Neutral	0.002
BRCA1	P38398-1.2	H1197N	Neutral	0.001
BRCA1	P38398-1.2	H1197P	Neutral	0.003
BRCA1	P38398-1.2	H1197Q	Neutral	0.001
BRCA1	P38398-1.2	H1197R	Neutral	0.002
BRCA1	P38398-1.2	H1197S	Neutral	0.003
BRCA1	P38398-1.2	H1197T	Neutral	0.003
BRCA1	P38398-1.2	H1197V	Neutral	0.003
BRCA1	P38398-1.2	H1197W	Neutral	0.005
BRCA1	P38398-1.2	H1197Y	Neutral	0.001
BRCA1	P38398-1.2	L1198A	Pathogenic	0.874
BRCA1	P38398-1.2	L1198C	Pathogenic	0.821
BRCA1	P38398-1.2	L1198D	Pathogenic	0.922
BRCA1	P38398-1.2	L1198E	Pathogenic	0.847
BRCA1	P38398-1.2	L1198F	Pathogenic	0.64
BRCA1	P38398-1.2	L1198G	Pathogenic	0.969
BRCA1	P38398-1.2	L1198H	Pathogenic	0.821
BRCA1	P38398-1.2	L1198I	Neutral	0.402
BRCA1	P38398-1.2	L1198K	Pathogenic	0.778
BRCA1	P38398-1.2	L1198M	Neutral	0.4
BRCA1	P38398-1.2	L1198N	Pathogenic	0.881
BRCA1	P38398-1.2	L1198P	Pathogenic	0.897
BRCA1	P38398-1.2	L1198Q	Pathogenic	0.776
BRCA1	P38398-1.2	L1198R	Pathogenic	0.823
BRCA1	P38398-1.2	L1198S	Pathogenic	0.896
BRCA1	P38398-1.2	L1198T	Pathogenic	0.795
BRCA1	P38398-1.2	L1198V	Pathogenic	0.594
BRCA1	P38398-1.2	L1198W	Pathogenic	0.872
BRCA1	P38398-1.2	L1198Y	Pathogenic	0.742
BRCA1	P38398-1.2	A1199C	Neutral	0.08
BRCA1	P38398-1.2	A1199D	Neutral	0.167
BRCA1	P38398-1.2	A1199E	Neutral	0.172
BRCA1	P38398-1.2	A1199F	Neutral	0.345
BRCA1	P38398-1.2	A1199G	Neutral	0.081
BRCA1	P38398-1.2	A1199H	Neutral	0.27
BRCA1	P38398-1.2	A1199I	Neutral	0.223
BRCA1	P38398-1.2	A1199K	Neutral	0.269
BRCA1	P38398-1.2	A1199L	Neutral	0.223
BRCA1	P38398-1.2	A1199M	Neutral	0.225
BRCA1	P38398-1.2	A1199N	Neutral	0.183
BRCA1	P38398-1.2	A1199P	Neutral	0.121
BRCA1	P38398-1.2	A1199Q	Neutral	0.19
BRCA1	P38398-1.2	A1199R	Neutral	0.329
BRCA1	P38398-1.2	A1199S	Neutral	0.044
BRCA1	P38398-1.2	A1199T	Neutral	0.093
BRCA1	P38398-1.2	A1199V	Neutral	0.117
BRCA1	P38398-1.2	A1199W	Pathogenic	0.584
BRCA1	P38398-1.2	A1199Y	Neutral	0.38
BRCA1	P38398-1.2	Q1200A	Neutral	0.393
BRCA1	P38398-1.2	Q1200C	Neutral	0.465
BRCA1	P38398-1.2	Q1200D	Neutral	0.209
BRCA1	P38398-1.2	Q1200E	Neutral	0.079
BRCA1	P38398-1.2	Q1200F	Neutral	0.422
BRCA1	P38398-1.2	Q1200G	Pathogenic	0.588
BRCA1	P38398-1.2	Q1200H	Neutral	0.148
BRCA1	P38398-1.2	Q1200I	Neutral	0.364
BRCA1	P38398-1.2	Q1200K	Neutral	0.149
BRCA1	P38398-1.2	Q1200L	Neutral	0.285
BRCA1	P38398-1.2	Q1200M	Neutral	0.163
BRCA1	P38398-1.2	Q1200N	Neutral	0.191
BRCA1	P38398-1.2	Q1200P	Neutral	0.278
BRCA1	P38398-1.2	Q1200R	Neutral	0.189
BRCA1	P38398-1.2	Q1200S	Neutral	0.284
BRCA1	P38398-1.2	Q1200T	Neutral	0.267
BRCA1	P38398-1.2	Q1200V	Neutral	0.282
BRCA1	P38398-1.2	Q1200W	Neutral	0.484
BRCA1	P38398-1.2	Q1200Y	Neutral	0.291
BRCA1	P38398-1.2	G1201A	Neutral	0.061
BRCA1	P38398-1.2	G1201C	Neutral	0.226
BRCA1	P38398-1.2	G1201D	Neutral	0.137
BRCA1	P38398-1.2	G1201E	Neutral	0.254
BRCA1	P38398-1.2	G1201F	Neutral	0.46
BRCA1	P38398-1.2	G1201H	Neutral	0.296
BRCA1	P38398-1.2	G1201I	Neutral	0.49
BRCA1	P38398-1.2	G1201K	Neutral	0.376
BRCA1	P38398-1.2	G1201L	Neutral	0.491
BRCA1	P38398-1.2	G1201M	Neutral	0.403
BRCA1	P38398-1.2	G1201N	Neutral	0.11
BRCA1	P38398-1.2	G1201P	Neutral	0.182
BRCA1	P38398-1.2	G1201Q	Neutral	0.277
BRCA1	P38398-1.2	G1201R	Neutral	0.446
BRCA1	P38398-1.2	G1201S	Neutral	0.07
BRCA1	P38398-1.2	G1201T	Neutral	0.194
BRCA1	P38398-1.2	G1201V	Neutral	0.307
BRCA1	P38398-1.2	G1201W	Pathogenic	0.523
BRCA1	P38398-1.2	G1201Y	Neutral	0.498
BRCA1	P38398-1.2	Y1202A	Neutral	0.044
BRCA1	P38398-1.2	Y1202C	Neutral	0.029
BRCA1	P38398-1.2	Y1202D	Neutral	0.036
BRCA1	P38398-1.2	Y1202E	Neutral	0.017
BRCA1	P38398-1.2	Y1202F	Neutral	0.002
BRCA1	P38398-1.2	Y1202G	Neutral	0.091
BRCA1	P38398-1.2	Y1202H	Neutral	0.003
BRCA1	P38398-1.2	Y1202I	Neutral	0.009
BRCA1	P38398-1.2	Y1202K	Neutral	0.01
BRCA1	P38398-1.2	Y1202L	Neutral	0.009
BRCA1	P38398-1.2	Y1202M	Neutral	0.009
BRCA1	P38398-1.2	Y1202N	Neutral	0.023
BRCA1	P38398-1.2	Y1202P	Neutral	0.038
BRCA1	P38398-1.2	Y1202Q	Neutral	0.011
BRCA1	P38398-1.2	Y1202R	Neutral	0.01
BRCA1	P38398-1.2	Y1202S	Neutral	0.038
BRCA1	P38398-1.2	Y1202T	Neutral	0.025
BRCA1	P38398-1.2	Y1202V	Neutral	0.014
BRCA1	P38398-1.2	Y1202W	Neutral	0.003
BRCA1	P38398-1.2	R1203A	Neutral	0.103
BRCA1	P38398-1.2	R1203C	Neutral	0.133
BRCA1	P38398-1.2	R1203D	Neutral	0.09
BRCA1	P38398-1.2	R1203E	Neutral	0.031
BRCA1	P38398-1.2	R1203F	Neutral	0.048
BRCA1	P38398-1.2	R1203G	Neutral	0.202
BRCA1	P38398-1.2	R1203H	Neutral	0.025
BRCA1	P38398-1.2	R1203I	Neutral	0.061
BRCA1	P38398-1.2	R1203K	Neutral	0.009
BRCA1	P38398-1.2	R1203L	Neutral	0.043
BRCA1	P38398-1.2	R1203M	Neutral	0.031
BRCA1	P38398-1.2	R1203N	Neutral	0.041
BRCA1	P38398-1.2	R1203P	Neutral	0.089
BRCA1	P38398-1.2	R1203Q	Neutral	0.019
BRCA1	P38398-1.2	R1203S	Neutral	0.092
BRCA1	P38398-1.2	R1203T	Neutral	0.06
BRCA1	P38398-1.2	R1203V	Neutral	0.091
BRCA1	P38398-1.2	R1203W	Neutral	0.05
BRCA1	P38398-1.2	R1203Y	Neutral	0.031
BRCA1	P38398-1.2	R1204A	Pathogenic	0.878
BRCA1	P38398-1.2	R1204C	Pathogenic	0.906
BRCA1	P38398-1.2	R1204D	Pathogenic	0.861
BRCA1	P38398-1.2	R1204E	Pathogenic	0.666
BRCA1	P38398-1.2	R1204F	Pathogenic	0.761
BRCA1	P38398-1.2	R1204G	Pathogenic	0.941
BRCA1	P38398-1.2	R1204H	Pathogenic	0.617
BRCA1	P38398-1.2	R1204I	Pathogenic	0.803
BRCA1	P38398-1.2	R1204K	Neutral	0.352
BRCA1	P38398-1.2	R1204L	Pathogenic	0.739
BRCA1	P38398-1.2	R1204M	Pathogenic	0.665
BRCA1	P38398-1.2	R1204N	Pathogenic	0.727
BRCA1	P38398-1.2	R1204P	Pathogenic	0.86
BRCA1	P38398-1.2	R1204Q	Pathogenic	0.552
BRCA1	P38398-1.2	R1204S	Pathogenic	0.863
BRCA1	P38398-1.2	R1204T	Pathogenic	0.801
BRCA1	P38398-1.2	R1204V	Pathogenic	0.862
BRCA1	P38398-1.2	R1204W	Pathogenic	0.767
BRCA1	P38398-1.2	R1204Y	Pathogenic	0.663
BRCA1	P38398-1.2	G1205A	Neutral	0.024
BRCA1	P38398-1.2	G1205C	Neutral	0.101
BRCA1	P38398-1.2	G1205D	Neutral	0.057
BRCA1	P38398-1.2	G1205E	Neutral	0.116
BRCA1	P38398-1.2	G1205F	Neutral	0.247
BRCA1	P38398-1.2	G1205H	Neutral	0.139
BRCA1	P38398-1.2	G1205I	Neutral	0.27
BRCA1	P38398-1.2	G1205K	Neutral	0.188
BRCA1	P38398-1.2	G1205L	Neutral	0.27
BRCA1	P38398-1.2	G1205M	Neutral	0.206
BRCA1	P38398-1.2	G1205N	Neutral	0.045
BRCA1	P38398-1.2	G1205P	Neutral	0.079
BRCA1	P38398-1.2	G1205Q	Neutral	0.129
BRCA1	P38398-1.2	G1205R	Neutral	0.236
BRCA1	P38398-1.2	G1205S	Neutral	0.028
BRCA1	P38398-1.2	G1205T	Neutral	0.085
BRCA1	P38398-1.2	G1205V	Neutral	0.146
BRCA1	P38398-1.2	G1205W	Neutral	0.296
BRCA1	P38398-1.2	G1205Y	Neutral	0.276
BRCA1	P38398-1.2	A1206C	Neutral	0.331
BRCA1	P38398-1.2	A1206D	Pathogenic	0.532
BRCA1	P38398-1.2	A1206E	Pathogenic	0.541
BRCA1	P38398-1.2	A1206F	Pathogenic	0.75
BRCA1	P38398-1.2	A1206G	Neutral	0.332
BRCA1	P38398-1.2	A1206H	Pathogenic	0.678
BRCA1	P38398-1.2	A1206I	Pathogenic	0.619
BRCA1	P38398-1.2	A1206K	Pathogenic	0.676
BRCA1	P38398-1.2	A1206L	Pathogenic	0.62
BRCA1	P38398-1.2	A1206M	Pathogenic	0.622
BRCA1	P38398-1.2	A1206N	Pathogenic	0.56
BRCA1	P38398-1.2	A1206P	Neutral	0.439
BRCA1	P38398-1.2	A1206Q	Pathogenic	0.57
BRCA1	P38398-1.2	A1206R	Pathogenic	0.736
BRCA1	P38398-1.2	A1206S	Neutral	0.206
BRCA1	P38398-1.2	A1206T	Neutral	0.369
BRCA1	P38398-1.2	A1206V	Neutral	0.429
BRCA1	P38398-1.2	A1206W	Pathogenic	0.888
BRCA1	P38398-1.2	A1206Y	Pathogenic	0.776
BRCA1	P38398-1.2	K1207A	Neutral	0.104
BRCA1	P38398-1.2	K1207C	Neutral	0.135
BRCA1	P38398-1.2	K1207D	Neutral	0.065
BRCA1	P38398-1.2	K1207E	Neutral	0.022
BRCA1	P38398-1.2	K1207F	Neutral	0.049
BRCA1	P38398-1.2	K1207G	Neutral	0.204
BRCA1	P38398-1.2	K1207H	Neutral	0.036
BRCA1	P38398-1.2	K1207I	Neutral	0.062
BRCA1	P38398-1.2	K1207L	Neutral	0.044
BRCA1	P38398-1.2	K1207M	Neutral	0.031
BRCA1	P38398-1.2	K1207N	Neutral	0.041
BRCA1	P38398-1.2	K1207P	Neutral	0.065
BRCA1	P38398-1.2	K1207Q	Neutral	0.02
BRCA1	P38398-1.2	K1207R	Neutral	0.012
BRCA1	P38398-1.2	K1207S	Neutral	0.066
BRCA1	P38398-1.2	K1207T	Neutral	0.061
BRCA1	P38398-1.2	K1207V	Neutral	0.066
BRCA1	P38398-1.2	K1207W	Neutral	0.087
BRCA1	P38398-1.2	K1207Y	Neutral	0.04
BRCA1	P38398-1.2	K1208A	Pathogenic	0.927
BRCA1	P38398-1.2	K1208C	Pathogenic	0.944
BRCA1	P38398-1.2	K1208D	Pathogenic	0.883
BRCA1	P38398-1.2	K1208E	Pathogenic	0.709
BRCA1	P38398-1.2	K1208F	Pathogenic	0.849
BRCA1	P38398-1.2	K1208G	Pathogenic	0.965
BRCA1	P38398-1.2	K1208H	Pathogenic	0.803
BRCA1	P38398-1.2	K1208I	Pathogenic	0.877
BRCA1	P38398-1.2	K1208L	Pathogenic	0.833
BRCA1	P38398-1.2	K1208M	Pathogenic	0.777
BRCA1	P38398-1.2	K1208N	Pathogenic	0.824
BRCA1	P38398-1.2	K1208P	Pathogenic	0.882
BRCA1	P38398-1.2	K1208Q	Pathogenic	0.684
BRCA1	P38398-1.2	K1208R	Pathogenic	0.561
BRCA1	P38398-1.2	K1208S	Pathogenic	0.885
BRCA1	P38398-1.2	K1208T	Pathogenic	0.876
BRCA1	P38398-1.2	K1208V	Pathogenic	0.885
BRCA1	P38398-1.2	K1208W	Pathogenic	0.912
BRCA1	P38398-1.2	K1208Y	Pathogenic	0.819
BRCA1	P38398-1.2	L1209A	Pathogenic	0.967
BRCA1	P38398-1.2	L1209C	Pathogenic	0.951
BRCA1	P38398-1.2	L1209D	Pathogenic	0.98
BRCA1	P38398-1.2	L1209E	Pathogenic	0.959
BRCA1	P38398-1.2	L1209F	Pathogenic	0.882
BRCA1	P38398-1.2	L1209G	Pathogenic	0.992
BRCA1	P38398-1.2	L1209H	Pathogenic	0.951
BRCA1	P38398-1.2	L1209I	Pathogenic	0.739
BRCA1	P38398-1.2	L1209K	Pathogenic	0.937
BRCA1	P38398-1.2	L1209M	Pathogenic	0.738
BRCA1	P38398-1.2	L1209N	Pathogenic	0.969
BRCA1	P38398-1.2	L1209P	Pathogenic	0.973
BRCA1	P38398-1.2	L1209Q	Pathogenic	0.936
BRCA1	P38398-1.2	L1209R	Pathogenic	0.952
BRCA1	P38398-1.2	L1209S	Pathogenic	0.973
BRCA1	P38398-1.2	L1209T	Pathogenic	0.942
BRCA1	P38398-1.2	L1209V	Pathogenic	0.86
BRCA1	P38398-1.2	L1209W	Pathogenic	0.966
BRCA1	P38398-1.2	L1209Y	Pathogenic	0.924
BRCA1	P38398-1.2	E1210A	Pathogenic	0.892
BRCA1	P38398-1.2	E1210C	Pathogenic	0.941
BRCA1	P38398-1.2	E1210D	Pathogenic	0.623
BRCA1	P38398-1.2	E1210F	Pathogenic	0.921
BRCA1	P38398-1.2	E1210G	Pathogenic	0.948
BRCA1	P38398-1.2	E1210H	Pathogenic	0.735
BRCA1	P38398-1.2	E1210I	Pathogenic	0.901
BRCA1	P38398-1.2	E1210K	Pathogenic	0.739
BRCA1	P38398-1.2	E1210L	Pathogenic	0.901
BRCA1	P38398-1.2	E1210M	Pathogenic	0.865
BRCA1	P38398-1.2	E1210N	Pathogenic	0.754
BRCA1	P38398-1.2	E1210P	Pathogenic	0.831
BRCA1	P38398-1.2	E1210Q	Pathogenic	0.552
BRCA1	P38398-1.2	E1210R	Pathogenic	0.845
BRCA1	P38398-1.2	E1210S	Pathogenic	0.835
BRCA1	P38398-1.2	E1210T	Pathogenic	0.823
BRCA1	P38398-1.2	E1210V	Pathogenic	0.834
BRCA1	P38398-1.2	E1210W	Pathogenic	0.956
BRCA1	P38398-1.2	E1210Y	Pathogenic	0.904
BRCA1	P38398-1.2	S1211A	Neutral	0.265
BRCA1	P38398-1.2	S1211C	Neutral	0.462
BRCA1	P38398-1.2	S1211D	Neutral	0.402
BRCA1	P38398-1.2	S1211E	Pathogenic	0.501
BRCA1	P38398-1.2	S1211F	Pathogenic	0.783
BRCA1	P38398-1.2	S1211G	Neutral	0.443
BRCA1	P38398-1.2	S1211H	Pathogenic	0.64
BRCA1	P38398-1.2	S1211I	Pathogenic	0.739
BRCA1	P38398-1.2	S1211K	Pathogenic	0.64
BRCA1	P38398-1.2	S1211L	Pathogenic	0.739
BRCA1	P38398-1.2	S1211M	Pathogenic	0.665
BRCA1	P38398-1.2	S1211N	Neutral	0.343
BRCA1	P38398-1.2	S1211P	Neutral	0.486
BRCA1	P38398-1.2	S1211Q	Pathogenic	0.531
BRCA1	P38398-1.2	S1211R	Pathogenic	0.773
BRCA1	P38398-1.2	S1211T	Neutral	0.33
BRCA1	P38398-1.2	S1211V	Pathogenic	0.652
BRCA1	P38398-1.2	S1211W	Pathogenic	0.906
BRCA1	P38398-1.2	S1211Y	Pathogenic	0.808
BRCA1	P38398-1.2	S1212A	Pathogenic	0.692
BRCA1	P38398-1.2	S1212C	Pathogenic	0.843
BRCA1	P38398-1.2	S1212D	Pathogenic	0.808
BRCA1	P38398-1.2	S1212E	Pathogenic	0.863
BRCA1	P38398-1.2	S1212F	Pathogenic	0.958
BRCA1	P38398-1.2	S1212G	Pathogenic	0.833
BRCA1	P38398-1.2	S1212H	Pathogenic	0.918
BRCA1	P38398-1.2	S1212I	Pathogenic	0.947
BRCA1	P38398-1.2	S1212K	Pathogenic	0.917
BRCA1	P38398-1.2	S1212L	Pathogenic	0.947
BRCA1	P38398-1.2	S1212M	Pathogenic	0.926
BRCA1	P38398-1.2	S1212N	Pathogenic	0.766
BRCA1	P38398-1.2	S1212P	Pathogenic	0.855
BRCA1	P38398-1.2	S1212Q	Pathogenic	0.876
BRCA1	P38398-1.2	S1212R	Pathogenic	0.955
BRCA1	P38398-1.2	S1212T	Pathogenic	0.755
BRCA1	P38398-1.2	S1212V	Pathogenic	0.922
BRCA1	P38398-1.2	S1212W	Pathogenic	0.984
BRCA1	P38398-1.2	S1212Y	Pathogenic	0.963
BRCA1	P38398-1.2	E1213A	Pathogenic	0.841
BRCA1	P38398-1.2	E1213C	Pathogenic	0.911
BRCA1	P38398-1.2	E1213D	Pathogenic	0.514
BRCA1	P38398-1.2	E1213F	Pathogenic	0.882
BRCA1	P38398-1.2	E1213G	Pathogenic	0.921
BRCA1	P38398-1.2	E1213H	Pathogenic	0.64
BRCA1	P38398-1.2	E1213I	Pathogenic	0.854
BRCA1	P38398-1.2	E1213K	Pathogenic	0.645
BRCA1	P38398-1.2	E1213L	Pathogenic	0.854
BRCA1	P38398-1.2	E1213M	Pathogenic	0.804
BRCA1	P38398-1.2	E1213N	Pathogenic	0.663
BRCA1	P38398-1.2	E1213P	Pathogenic	0.759
BRCA1	P38398-1.2	E1213Q	Neutral	0.441
BRCA1	P38398-1.2	E1213R	Pathogenic	0.777
BRCA1	P38398-1.2	E1213S	Pathogenic	0.764
BRCA1	P38398-1.2	E1213T	Pathogenic	0.749
BRCA1	P38398-1.2	E1213V	Pathogenic	0.763
BRCA1	P38398-1.2	E1213W	Pathogenic	0.932
BRCA1	P38398-1.2	E1213Y	Pathogenic	0.858
BRCA1	P38398-1.2	E1214A	Pathogenic	0.879
BRCA1	P38398-1.2	E1214C	Pathogenic	0.933
BRCA1	P38398-1.2	E1214D	Pathogenic	0.592
BRCA1	P38398-1.2	E1214F	Pathogenic	0.911
BRCA1	P38398-1.2	E1214G	Pathogenic	0.941
BRCA1	P38398-1.2	E1214H	Pathogenic	0.709
BRCA1	P38398-1.2	E1214I	Pathogenic	0.889
BRCA1	P38398-1.2	E1214K	Pathogenic	0.713
BRCA1	P38398-1.2	E1214L	Pathogenic	0.889
BRCA1	P38398-1.2	E1214M	Pathogenic	0.849
BRCA1	P38398-1.2	E1214N	Pathogenic	0.729
BRCA1	P38398-1.2	E1214P	Pathogenic	0.812
BRCA1	P38398-1.2	E1214Q	Pathogenic	0.52
BRCA1	P38398-1.2	E1214R	Pathogenic	0.827
BRCA1	P38398-1.2	E1214S	Pathogenic	0.816
BRCA1	P38398-1.2	E1214T	Pathogenic	0.803
BRCA1	P38398-1.2	E1214V	Pathogenic	0.815
BRCA1	P38398-1.2	E1214W	Pathogenic	0.95
BRCA1	P38398-1.2	E1214Y	Pathogenic	0.892
BRCA1	P38398-1.2	N1215A	Neutral	0.023
BRCA1	P38398-1.2	N1215C	Neutral	0.021
BRCA1	P38398-1.2	N1215D	Neutral	0.005
BRCA1	P38398-1.2	N1215E	Neutral	0.008
BRCA1	P38398-1.2	N1215F	Neutral	0.039
BRCA1	P38398-1.2	N1215G	Neutral	0.017
BRCA1	P38398-1.2	N1215H	Neutral	0.007
BRCA1	P38398-1.2	N1215I	Neutral	0.031
BRCA1	P38398-1.2	N1215K	Neutral	0.014
BRCA1	P38398-1.2	N1215L	Neutral	0.031
BRCA1	P38398-1.2	N1215M	Neutral	0.022
BRCA1	P38398-1.2	N1215P	Neutral	0.014
BRCA1	P38398-1.2	N1215Q	Neutral	0.009
BRCA1	P38398-1.2	N1215R	Neutral	0.019
BRCA1	P38398-1.2	N1215S	Neutral	0.007
BRCA1	P38398-1.2	N1215T	Neutral	0.006
BRCA1	P38398-1.2	N1215V	Neutral	0.021
BRCA1	P38398-1.2	N1215W	Neutral	0.097
BRCA1	P38398-1.2	N1215Y	Neutral	0.032
BRCA1	P38398-1.2	L1216A	Neutral	0.001
BRCA1	P38398-1.2	L1216C	Neutral	0.0
BRCA1	P38398-1.2	L1216D	Neutral	0.001
BRCA1	P38398-1.2	L1216E	Neutral	0.0
BRCA1	P38398-1.2	L1216F	Neutral	0.0
BRCA1	P38398-1.2	L1216G	Neutral	0.003
BRCA1	P38398-1.2	L1216H	Neutral	0.0
BRCA1	P38398-1.2	L1216I	Neutral	0.0
BRCA1	P38398-1.2	L1216K	Neutral	0.0
BRCA1	P38398-1.2	L1216M	Neutral	0.0
BRCA1	P38398-1.2	L1216N	Neutral	0.001
BRCA1	P38398-1.2	L1216P	Neutral	0.001
BRCA1	P38398-1.2	L1216Q	Neutral	0.0
BRCA1	P38398-1.2	L1216R	Neutral	0.0
BRCA1	P38398-1.2	L1216S	Neutral	0.001
BRCA1	P38398-1.2	L1216T	Neutral	0.0
BRCA1	P38398-1.2	L1216V	Neutral	0.0
BRCA1	P38398-1.2	L1216W	Neutral	0.001
BRCA1	P38398-1.2	L1216Y	Neutral	0.0
BRCA1	P38398-1.2	S1217A	Neutral	0.238
BRCA1	P38398-1.2	S1217C	Neutral	0.428
BRCA1	P38398-1.2	S1217D	Neutral	0.369
BRCA1	P38398-1.2	S1217E	Neutral	0.466
BRCA1	P38398-1.2	S1217F	Pathogenic	0.759
BRCA1	P38398-1.2	S1217G	Neutral	0.409
BRCA1	P38398-1.2	S1217H	Pathogenic	0.607
BRCA1	P38398-1.2	S1217I	Pathogenic	0.711
BRCA1	P38398-1.2	S1217K	Pathogenic	0.607
BRCA1	P38398-1.2	S1217L	Pathogenic	0.712
BRCA1	P38398-1.2	S1217M	Pathogenic	0.634
BRCA1	P38398-1.2	S1217N	Neutral	0.313
BRCA1	P38398-1.2	S1217P	Neutral	0.451
BRCA1	P38398-1.2	S1217Q	Neutral	0.496
BRCA1	P38398-1.2	S1217R	Pathogenic	0.748
BRCA1	P38398-1.2	S1217T	Neutral	0.3
BRCA1	P38398-1.2	S1217V	Pathogenic	0.62
BRCA1	P38398-1.2	S1217W	Pathogenic	0.893
BRCA1	P38398-1.2	S1217Y	Pathogenic	0.785
BRCA1	P38398-1.2	S1218A	Neutral	0.306
BRCA1	P38398-1.2	S1218C	Pathogenic	0.513
BRCA1	P38398-1.2	S1218D	Neutral	0.452
BRCA1	P38398-1.2	S1218E	Pathogenic	0.552
BRCA1	P38398-1.2	S1218F	Pathogenic	0.816
BRCA1	P38398-1.2	S1218G	Neutral	0.494
BRCA1	P38398-1.2	S1218H	Pathogenic	0.686
BRCA1	P38398-1.2	S1218I	Pathogenic	0.777
BRCA1	P38398-1.2	S1218K	Pathogenic	0.686
BRCA1	P38398-1.2	S1218L	Pathogenic	0.777
BRCA1	P38398-1.2	S1218M	Pathogenic	0.71
BRCA1	P38398-1.2	S1218N	Neutral	0.391
BRCA1	P38398-1.2	S1218P	Pathogenic	0.537
BRCA1	P38398-1.2	S1218Q	Pathogenic	0.581
BRCA1	P38398-1.2	S1218R	Pathogenic	0.807
BRCA1	P38398-1.2	S1218T	Neutral	0.376
BRCA1	P38398-1.2	S1218V	Pathogenic	0.697
BRCA1	P38398-1.2	S1218W	Pathogenic	0.922
BRCA1	P38398-1.2	S1218Y	Pathogenic	0.838
BRCA1	P38398-1.2	E1219A	Pathogenic	0.88
BRCA1	P38398-1.2	E1219C	Pathogenic	0.934
BRCA1	P38398-1.2	E1219D	Pathogenic	0.594
BRCA1	P38398-1.2	E1219F	Pathogenic	0.912
BRCA1	P38398-1.2	E1219G	Pathogenic	0.942
BRCA1	P38398-1.2	E1219H	Pathogenic	0.71
BRCA1	P38398-1.2	E1219I	Pathogenic	0.89
BRCA1	P38398-1.2	E1219K	Pathogenic	0.715
BRCA1	P38398-1.2	E1219L	Pathogenic	0.89
BRCA1	P38398-1.2	E1219M	Pathogenic	0.85
BRCA1	P38398-1.2	E1219N	Pathogenic	0.731
BRCA1	P38398-1.2	E1219P	Pathogenic	0.813
BRCA1	P38398-1.2	E1219Q	Pathogenic	0.521
BRCA1	P38398-1.2	E1219R	Pathogenic	0.828
BRCA1	P38398-1.2	E1219S	Pathogenic	0.817
BRCA1	P38398-1.2	E1219T	Pathogenic	0.804
BRCA1	P38398-1.2	E1219V	Pathogenic	0.816
BRCA1	P38398-1.2	E1219W	Pathogenic	0.95
BRCA1	P38398-1.2	E1219Y	Pathogenic	0.893
BRCA1	P38398-1.2	D1220A	Neutral	0.458
BRCA1	P38398-1.2	D1220C	Neutral	0.44
BRCA1	P38398-1.2	D1220E	Neutral	0.149
BRCA1	P38398-1.2	D1220F	Pathogenic	0.648
BRCA1	P38398-1.2	D1220G	Neutral	0.474
BRCA1	P38398-1.2	D1220H	Neutral	0.386
BRCA1	P38398-1.2	D1220I	Pathogenic	0.591
BRCA1	P38398-1.2	D1220K	Neutral	0.482
BRCA1	P38398-1.2	D1220L	Pathogenic	0.675
BRCA1	P38398-1.2	D1220M	Pathogenic	0.593
BRCA1	P38398-1.2	D1220N	Neutral	0.159
BRCA1	P38398-1.2	D1220P	Neutral	0.259
BRCA1	P38398-1.2	D1220Q	Neutral	0.287
BRCA1	P38398-1.2	D1220R	Pathogenic	0.641
BRCA1	P38398-1.2	D1220S	Neutral	0.264
BRCA1	P38398-1.2	D1220T	Neutral	0.265
BRCA1	P38398-1.2	D1220V	Neutral	0.489
BRCA1	P38398-1.2	D1220W	Pathogenic	0.83
BRCA1	P38398-1.2	D1220Y	Pathogenic	0.681
BRCA1	P38398-1.2	E1221A	Pathogenic	0.606
BRCA1	P38398-1.2	E1221C	Pathogenic	0.748
BRCA1	P38398-1.2	E1221D	Neutral	0.235
BRCA1	P38398-1.2	E1221F	Pathogenic	0.685
BRCA1	P38398-1.2	E1221G	Pathogenic	0.773
BRCA1	P38398-1.2	E1221H	Neutral	0.34
BRCA1	P38398-1.2	E1221I	Pathogenic	0.63
BRCA1	P38398-1.2	E1221K	Neutral	0.345
BRCA1	P38398-1.2	E1221L	Pathogenic	0.63
BRCA1	P38398-1.2	E1221M	Pathogenic	0.544
BRCA1	P38398-1.2	E1221N	Neutral	0.364
BRCA1	P38398-1.2	E1221P	Neutral	0.478
BRCA1	P38398-1.2	E1221Q	Neutral	0.187
BRCA1	P38398-1.2	E1221R	Pathogenic	0.503
BRCA1	P38398-1.2	E1221S	Neutral	0.485
BRCA1	P38398-1.2	E1221T	Neutral	0.464
BRCA1	P38398-1.2	E1221V	Neutral	0.483
BRCA1	P38398-1.2	E1221W	Pathogenic	0.8
BRCA1	P38398-1.2	E1221Y	Pathogenic	0.637
BRCA1	P38398-1.2	E1222A	Neutral	0.467
BRCA1	P38398-1.2	E1222C	Pathogenic	0.628
BRCA1	P38398-1.2	E1222D	Neutral	0.149
BRCA1	P38398-1.2	E1222F	Pathogenic	0.553
BRCA1	P38398-1.2	E1222G	Pathogenic	0.659
BRCA1	P38398-1.2	E1222H	Neutral	0.227
BRCA1	P38398-1.2	E1222I	Neutral	0.492
BRCA1	P38398-1.2	E1222K	Neutral	0.231
BRCA1	P38398-1.2	E1222L	Neutral	0.492
BRCA1	P38398-1.2	E1222M	Neutral	0.405
BRCA1	P38398-1.2	E1222N	Neutral	0.245
BRCA1	P38398-1.2	E1222P	Neutral	0.343
BRCA1	P38398-1.2	E1222Q	Neutral	0.115
BRCA1	P38398-1.2	E1222R	Neutral	0.365
BRCA1	P38398-1.2	E1222S	Neutral	0.349
BRCA1	P38398-1.2	E1222T	Neutral	0.33
BRCA1	P38398-1.2	E1222V	Neutral	0.347
BRCA1	P38398-1.2	E1222W	Pathogenic	0.695
BRCA1	P38398-1.2	E1222Y	Neutral	0.499
BRCA1	P38398-1.2	L1223A	Pathogenic	0.88
BRCA1	P38398-1.2	L1223C	Pathogenic	0.83
BRCA1	P38398-1.2	L1223D	Pathogenic	0.926
BRCA1	P38398-1.2	L1223E	Pathogenic	0.855
BRCA1	P38398-1.2	L1223F	Pathogenic	0.653
BRCA1	P38398-1.2	L1223G	Pathogenic	0.971
BRCA1	P38398-1.2	L1223H	Pathogenic	0.83
BRCA1	P38398-1.2	L1223I	Neutral	0.416
BRCA1	P38398-1.2	L1223K	Pathogenic	0.788
BRCA1	P38398-1.2	L1223M	Neutral	0.414
BRCA1	P38398-1.2	L1223N	Pathogenic	0.887
BRCA1	P38398-1.2	L1223P	Pathogenic	0.902
BRCA1	P38398-1.2	L1223Q	Pathogenic	0.787
BRCA1	P38398-1.2	L1223R	Pathogenic	0.832
BRCA1	P38398-1.2	L1223S	Pathogenic	0.902
BRCA1	P38398-1.2	L1223T	Pathogenic	0.805
BRCA1	P38398-1.2	L1223V	Pathogenic	0.608
BRCA1	P38398-1.2	L1223W	Pathogenic	0.878
BRCA1	P38398-1.2	L1223Y	Pathogenic	0.754
BRCA1	P38398-1.2	P1224A	Pathogenic	0.727
BRCA1	P38398-1.2	P1224C	Pathogenic	0.784
BRCA1	P38398-1.2	P1224D	Pathogenic	0.615
BRCA1	P38398-1.2	P1224E	Pathogenic	0.705
BRCA1	P38398-1.2	P1224F	Pathogenic	0.927
BRCA1	P38398-1.2	P1224G	Pathogenic	0.853
BRCA1	P38398-1.2	P1224H	Pathogenic	0.81
BRCA1	P38398-1.2	P1224I	Pathogenic	0.874
BRCA1	P38398-1.2	P1224K	Pathogenic	0.809
BRCA1	P38398-1.2	P1224L	Pathogenic	0.874
BRCA1	P38398-1.2	P1224M	Pathogenic	0.83
BRCA1	P38398-1.2	P1224N	Pathogenic	0.721
BRCA1	P38398-1.2	P1224Q	Pathogenic	0.729
BRCA1	P38398-1.2	P1224R	Pathogenic	0.89
BRCA1	P38398-1.2	P1224S	Pathogenic	0.698
BRCA1	P38398-1.2	P1224T	Pathogenic	0.63
BRCA1	P38398-1.2	P1224V	Pathogenic	0.762
BRCA1	P38398-1.2	P1224W	Pathogenic	0.959
BRCA1	P38398-1.2	P1224Y	Pathogenic	0.911
BRCA1	P38398-1.2	C1225A	Neutral	0.49
BRCA1	P38398-1.2	C1225D	Pathogenic	0.673
BRCA1	P38398-1.2	C1225E	Pathogenic	0.816
BRCA1	P38398-1.2	C1225F	Pathogenic	0.794
BRCA1	P38398-1.2	C1225G	Pathogenic	0.813
BRCA1	P38398-1.2	C1225H	Pathogenic	0.792
BRCA1	P38398-1.2	C1225I	Pathogenic	0.678
BRCA1	P38398-1.2	C1225K	Pathogenic	0.845
BRCA1	P38398-1.2	C1225L	Pathogenic	0.678
BRCA1	P38398-1.2	C1225M	Pathogenic	0.68
BRCA1	P38398-1.2	C1225N	Pathogenic	0.697
BRCA1	P38398-1.2	C1225P	Pathogenic	0.674
BRCA1	P38398-1.2	C1225Q	Pathogenic	0.776
BRCA1	P38398-1.2	C1225R	Pathogenic	0.879
BRCA1	P38398-1.2	C1225S	Pathogenic	0.546
BRCA1	P38398-1.2	C1225T	Pathogenic	0.514
BRCA1	P38398-1.2	C1225V	Pathogenic	0.582
BRCA1	P38398-1.2	C1225W	Pathogenic	0.877
BRCA1	P38398-1.2	C1225Y	Pathogenic	0.818
BRCA1	P38398-1.2	F1226A	Pathogenic	0.951
BRCA1	P38398-1.2	F1226C	Pathogenic	0.929
BRCA1	P38398-1.2	F1226D	Pathogenic	0.942
BRCA1	P38398-1.2	F1226E	Pathogenic	0.916
BRCA1	P38398-1.2	F1226G	Pathogenic	0.977
BRCA1	P38398-1.2	F1226H	Pathogenic	0.814
BRCA1	P38398-1.2	F1226I	Pathogenic	0.733
BRCA1	P38398-1.2	F1226K	Pathogenic	0.858
BRCA1	P38398-1.2	F1226L	Pathogenic	0.732
BRCA1	P38398-1.2	F1226M	Pathogenic	0.731
BRCA1	P38398-1.2	F1226N	Pathogenic	0.936
BRCA1	P38398-1.2	F1226P	Pathogenic	0.961
BRCA1	P38398-1.2	F1226Q	Pathogenic	0.908
BRCA1	P38398-1.2	F1226R	Pathogenic	0.89
BRCA1	P38398-1.2	F1226S	Pathogenic	0.944
BRCA1	P38398-1.2	F1226T	Pathogenic	0.916
BRCA1	P38398-1.2	F1226V	Pathogenic	0.856
BRCA1	P38398-1.2	F1226W	Pathogenic	0.734
BRCA1	P38398-1.2	F1226Y	Neutral	0.448
BRCA1	P38398-1.2	Q1227A	Pathogenic	0.806
BRCA1	P38398-1.2	Q1227C	Pathogenic	0.847
BRCA1	P38398-1.2	Q1227D	Pathogenic	0.628
BRCA1	P38398-1.2	Q1227E	Neutral	0.354
BRCA1	P38398-1.2	Q1227F	Pathogenic	0.824
BRCA1	P38398-1.2	Q1227G	Pathogenic	0.901
BRCA1	P38398-1.2	Q1227H	Pathogenic	0.526
BRCA1	P38398-1.2	Q1227I	Pathogenic	0.786
BRCA1	P38398-1.2	Q1227K	Pathogenic	0.528
BRCA1	P38398-1.2	Q1227L	Pathogenic	0.718
BRCA1	P38398-1.2	Q1227M	Pathogenic	0.554
BRCA1	P38398-1.2	Q1227N	Pathogenic	0.602
BRCA1	P38398-1.2	Q1227P	Pathogenic	0.711
BRCA1	P38398-1.2	Q1227R	Pathogenic	0.599
BRCA1	P38398-1.2	Q1227S	Pathogenic	0.717
BRCA1	P38398-1.2	Q1227T	Pathogenic	0.699
BRCA1	P38398-1.2	Q1227V	Pathogenic	0.716
BRCA1	P38398-1.2	Q1227W	Pathogenic	0.857
BRCA1	P38398-1.2	Q1227Y	Pathogenic	0.724
BRCA1	P38398-1.2	H1228A	Pathogenic	0.746
BRCA1	P38398-1.2	H1228C	Pathogenic	0.732
BRCA1	P38398-1.2	H1228D	Pathogenic	0.541
BRCA1	P38398-1.2	H1228E	Neutral	0.355
BRCA1	P38398-1.2	H1228F	Neutral	0.482
BRCA1	P38398-1.2	H1228G	Pathogenic	0.818
BRCA1	P38398-1.2	H1228I	Pathogenic	0.602
BRCA1	P38398-1.2	H1228K	Neutral	0.485
BRCA1	P38398-1.2	H1228L	Pathogenic	0.602
BRCA1	P38398-1.2	H1228M	Pathogenic	0.515
BRCA1	P38398-1.2	H1228N	Neutral	0.338
BRCA1	P38398-1.2	H1228P	Pathogenic	0.636
BRCA1	P38398-1.2	H1228Q	Neutral	0.332
BRCA1	P38398-1.2	H1228R	Neutral	0.466
BRCA1	P38398-1.2	H1228S	Pathogenic	0.641
BRCA1	P38398-1.2	H1228T	Pathogenic	0.623
BRCA1	P38398-1.2	H1228V	Pathogenic	0.641
BRCA1	P38398-1.2	H1228W	Pathogenic	0.712
BRCA1	P38398-1.2	H1228Y	Neutral	0.266
BRCA1	P38398-1.2	L1229A	Pathogenic	0.748
BRCA1	P38398-1.2	L1229C	Pathogenic	0.663
BRCA1	P38398-1.2	L1229D	Pathogenic	0.836
BRCA1	P38398-1.2	L1229E	Pathogenic	0.704
BRCA1	P38398-1.2	L1229F	Neutral	0.432
BRCA1	P38398-1.2	L1229G	Pathogenic	0.931
BRCA1	P38398-1.2	L1229H	Pathogenic	0.664
BRCA1	P38398-1.2	L1229I	Neutral	0.223
BRCA1	P38398-1.2	L1229K	Pathogenic	0.6
BRCA1	P38398-1.2	L1229M	Neutral	0.222
BRCA1	P38398-1.2	L1229N	Pathogenic	0.76
BRCA1	P38398-1.2	L1229P	Pathogenic	0.788
BRCA1	P38398-1.2	L1229Q	Pathogenic	0.598
BRCA1	P38398-1.2	L1229R	Pathogenic	0.667
BRCA1	P38398-1.2	L1229S	Pathogenic	0.788
BRCA1	P38398-1.2	L1229T	Pathogenic	0.625
BRCA1	P38398-1.2	L1229V	Neutral	0.385
BRCA1	P38398-1.2	L1229W	Pathogenic	0.744
BRCA1	P38398-1.2	L1229Y	Pathogenic	0.553
BRCA1	P38398-1.2	L1230A	Neutral	0.393
BRCA1	P38398-1.2	L1230C	Neutral	0.301
BRCA1	P38398-1.2	L1230D	Pathogenic	0.526
BRCA1	P38398-1.2	L1230E	Neutral	0.341
BRCA1	P38398-1.2	L1230F	Neutral	0.142
BRCA1	P38398-1.2	L1230G	Pathogenic	0.745
BRCA1	P38398-1.2	L1230H	Neutral	0.301
BRCA1	P38398-1.2	L1230I	Neutral	0.059
BRCA1	P38398-1.2	L1230K	Neutral	0.246
BRCA1	P38398-1.2	L1230M	Neutral	0.059
BRCA1	P38398-1.2	L1230N	Neutral	0.409
BRCA1	P38398-1.2	L1230P	Neutral	0.448
BRCA1	P38398-1.2	L1230Q	Neutral	0.245
BRCA1	P38398-1.2	L1230R	Neutral	0.304
BRCA1	P38398-1.2	L1230S	Neutral	0.447
BRCA1	P38398-1.2	L1230T	Neutral	0.266
BRCA1	P38398-1.2	L1230V	Neutral	0.12
BRCA1	P38398-1.2	L1230W	Neutral	0.388
BRCA1	P38398-1.2	L1230Y	Neutral	0.212
BRCA1	P38398-1.2	F1231A	Pathogenic	0.934
BRCA1	P38398-1.2	F1231C	Pathogenic	0.903
BRCA1	P38398-1.2	F1231D	Pathogenic	0.921
BRCA1	P38398-1.2	F1231E	Pathogenic	0.887
BRCA1	P38398-1.2	F1231G	Pathogenic	0.968
BRCA1	P38398-1.2	F1231H	Pathogenic	0.759
BRCA1	P38398-1.2	F1231I	Pathogenic	0.664
BRCA1	P38398-1.2	F1231K	Pathogenic	0.814
BRCA1	P38398-1.2	F1231L	Pathogenic	0.663
BRCA1	P38398-1.2	F1231M	Pathogenic	0.661
BRCA1	P38398-1.2	F1231N	Pathogenic	0.913
BRCA1	P38398-1.2	F1231P	Pathogenic	0.946
BRCA1	P38398-1.2	F1231Q	Pathogenic	0.876
BRCA1	P38398-1.2	F1231R	Pathogenic	0.854
BRCA1	P38398-1.2	F1231S	Pathogenic	0.925
BRCA1	P38398-1.2	F1231T	Pathogenic	0.888
BRCA1	P38398-1.2	F1231V	Pathogenic	0.811
BRCA1	P38398-1.2	F1231W	Pathogenic	0.665
BRCA1	P38398-1.2	F1231Y	Neutral	0.368
BRCA1	P38398-1.2	G1232A	Neutral	0.311
BRCA1	P38398-1.2	G1232C	Pathogenic	0.669
BRCA1	P38398-1.2	G1232D	Pathogenic	0.523
BRCA1	P38398-1.2	G1232E	Pathogenic	0.702
BRCA1	P38398-1.2	G1232F	Pathogenic	0.855
BRCA1	P38398-1.2	G1232H	Pathogenic	0.744
BRCA1	P38398-1.2	G1232I	Pathogenic	0.87
BRCA1	P38398-1.2	G1232K	Pathogenic	0.807
BRCA1	P38398-1.2	G1232L	Pathogenic	0.87
BRCA1	P38398-1.2	G1232M	Pathogenic	0.824
BRCA1	P38398-1.2	G1232N	Neutral	0.461
BRCA1	P38398-1.2	G1232P	Pathogenic	0.607
BRCA1	P38398-1.2	G1232Q	Pathogenic	0.727
BRCA1	P38398-1.2	G1232R	Pathogenic	0.848
BRCA1	P38398-1.2	G1232S	Neutral	0.341
BRCA1	P38398-1.2	G1232T	Pathogenic	0.625
BRCA1	P38398-1.2	G1232V	Pathogenic	0.755
BRCA1	P38398-1.2	G1232W	Pathogenic	0.884
BRCA1	P38398-1.2	G1232Y	Pathogenic	0.873
BRCA1	P38398-1.2	K1233A	Pathogenic	0.571
BRCA1	P38398-1.2	K1233C	Pathogenic	0.641
BRCA1	P38398-1.2	K1233D	Neutral	0.444
BRCA1	P38398-1.2	K1233E	Neutral	0.205
BRCA1	P38398-1.2	K1233F	Neutral	0.372
BRCA1	P38398-1.2	K1233G	Pathogenic	0.746
BRCA1	P38398-1.2	K1233H	Neutral	0.301
BRCA1	P38398-1.2	K1233I	Neutral	0.431
BRCA1	P38398-1.2	K1233L	Neutral	0.345
BRCA1	P38398-1.2	K1233M	Neutral	0.27
BRCA1	P38398-1.2	K1233N	Neutral	0.331
BRCA1	P38398-1.2	K1233P	Neutral	0.443
BRCA1	P38398-1.2	K1233Q	Neutral	0.186
BRCA1	P38398-1.2	K1233R	Neutral	0.119
BRCA1	P38398-1.2	K1233S	Neutral	0.449
BRCA1	P38398-1.2	K1233T	Neutral	0.428
BRCA1	P38398-1.2	K1233V	Neutral	0.448
BRCA1	P38398-1.2	K1233W	Pathogenic	0.523
BRCA1	P38398-1.2	K1233Y	Neutral	0.324
BRCA1	P38398-1.2	V1234A	Neutral	0.097
BRCA1	P38398-1.2	V1234C	Neutral	0.093
BRCA1	P38398-1.2	V1234D	Neutral	0.155
BRCA1	P38398-1.2	V1234E	Neutral	0.093
BRCA1	P38398-1.2	V1234F	Neutral	0.115
BRCA1	P38398-1.2	V1234G	Neutral	0.327
BRCA1	P38398-1.2	V1234H	Neutral	0.155
BRCA1	P38398-1.2	V1234I	Neutral	0.023
BRCA1	P38398-1.2	V1234K	Neutral	0.154
BRCA1	P38398-1.2	V1234L	Neutral	0.047
BRCA1	P38398-1.2	V1234M	Neutral	0.047
BRCA1	P38398-1.2	V1234N	Neutral	0.142
BRCA1	P38398-1.2	V1234P	Neutral	0.119
BRCA1	P38398-1.2	V1234Q	Neutral	0.104
BRCA1	P38398-1.2	V1234R	Neutral	0.258
BRCA1	P38398-1.2	V1234S	Neutral	0.162
BRCA1	P38398-1.2	V1234T	Neutral	0.057
BRCA1	P38398-1.2	V1234W	Neutral	0.332
BRCA1	P38398-1.2	V1234Y	Neutral	0.13
BRCA1	P38398-1.2	N1235A	Neutral	0.001
BRCA1	P38398-1.2	N1235C	Neutral	0.001
BRCA1	P38398-1.2	N1235D	Neutral	0.0
BRCA1	P38398-1.2	N1235E	Neutral	0.0
BRCA1	P38398-1.2	N1235F	Neutral	0.002
BRCA1	P38398-1.2	N1235G	Neutral	0.001
BRCA1	P38398-1.2	N1235H	Neutral	0.0
BRCA1	P38398-1.2	N1235I	Neutral	0.002
BRCA1	P38398-1.2	N1235K	Neutral	0.001
BRCA1	P38398-1.2	N1235L	Neutral	0.002
BRCA1	P38398-1.2	N1235M	Neutral	0.001
BRCA1	P38398-1.2	N1235P	Neutral	0.001
BRCA1	P38398-1.2	N1235Q	Neutral	0.001
BRCA1	P38398-1.2	N1235R	Neutral	0.001
BRCA1	P38398-1.2	N1235S	Neutral	0.0
BRCA1	P38398-1.2	N1235T	Neutral	0.0
BRCA1	P38398-1.2	N1235V	Neutral	0.001
BRCA1	P38398-1.2	N1235W	Neutral	0.006
BRCA1	P38398-1.2	N1235Y	Neutral	0.002
BRCA1	P38398-1.2	N1236A	Neutral	0.004
BRCA1	P38398-1.2	N1236C	Neutral	0.004
BRCA1	P38398-1.2	N1236D	Neutral	0.001
BRCA1	P38398-1.2	N1236E	Neutral	0.001
BRCA1	P38398-1.2	N1236F	Neutral	0.007
BRCA1	P38398-1.2	N1236G	Neutral	0.003
BRCA1	P38398-1.2	N1236H	Neutral	0.001
BRCA1	P38398-1.2	N1236I	Neutral	0.006
BRCA1	P38398-1.2	N1236K	Neutral	0.003
BRCA1	P38398-1.2	N1236L	Neutral	0.006
BRCA1	P38398-1.2	N1236M	Neutral	0.004
BRCA1	P38398-1.2	N1236P	Neutral	0.002
BRCA1	P38398-1.2	N1236Q	Neutral	0.002
BRCA1	P38398-1.2	N1236R	Neutral	0.003
BRCA1	P38398-1.2	N1236S	Neutral	0.001
BRCA1	P38398-1.2	N1236T	Neutral	0.001
BRCA1	P38398-1.2	N1236V	Neutral	0.004
BRCA1	P38398-1.2	N1236W	Neutral	0.019
BRCA1	P38398-1.2	N1236Y	Neutral	0.006
BRCA1	P38398-1.2	I1237A	Neutral	0.07
BRCA1	P38398-1.2	I1237C	Neutral	0.048
BRCA1	P38398-1.2	I1237D	Neutral	0.083
BRCA1	P38398-1.2	I1237E	Neutral	0.057
BRCA1	P38398-1.2	I1237F	Neutral	0.019
BRCA1	P38398-1.2	I1237G	Neutral	0.255
BRCA1	P38398-1.2	I1237H	Neutral	0.048
BRCA1	P38398-1.2	I1237K	Neutral	0.052
BRCA1	P38398-1.2	I1237L	Neutral	0.007
BRCA1	P38398-1.2	I1237M	Neutral	0.01
BRCA1	P38398-1.2	I1237N	Neutral	0.075
BRCA1	P38398-1.2	I1237P	Neutral	0.087
BRCA1	P38398-1.2	I1237Q	Neutral	0.052
BRCA1	P38398-1.2	I1237R	Neutral	0.068
BRCA1	P38398-1.2	I1237S	Neutral	0.087
BRCA1	P38398-1.2	I1237T	Neutral	0.041
BRCA1	P38398-1.2	I1237V	Neutral	0.008
BRCA1	P38398-1.2	I1237W	Neutral	0.097
BRCA1	P38398-1.2	I1237Y	Neutral	0.031
BRCA1	P38398-1.2	P1238A	Pathogenic	0.53
BRCA1	P38398-1.2	P1238C	Pathogenic	0.606
BRCA1	P38398-1.2	P1238D	Neutral	0.404
BRCA1	P38398-1.2	P1238E	Pathogenic	0.503
BRCA1	P38398-1.2	P1238F	Pathogenic	0.844
BRCA1	P38398-1.2	P1238G	Pathogenic	0.711
BRCA1	P38398-1.2	P1238H	Pathogenic	0.644
BRCA1	P38398-1.2	P1238I	Pathogenic	0.747
BRCA1	P38398-1.2	P1238K	Pathogenic	0.642
BRCA1	P38398-1.2	P1238L	Pathogenic	0.747
BRCA1	P38398-1.2	P1238M	Pathogenic	0.674
BRCA1	P38398-1.2	P1238N	Pathogenic	0.522
BRCA1	P38398-1.2	P1238Q	Pathogenic	0.533
BRCA1	P38398-1.2	P1238R	Pathogenic	0.775
BRCA1	P38398-1.2	P1238S	Neutral	0.495
BRCA1	P38398-1.2	P1238T	Neutral	0.42
BRCA1	P38398-1.2	P1238V	Pathogenic	0.576
BRCA1	P38398-1.2	P1238W	Pathogenic	0.909
BRCA1	P38398-1.2	P1238Y	Pathogenic	0.814
BRCA1	P38398-1.2	S1239A	Neutral	0.053
BRCA1	P38398-1.2	S1239C	Neutral	0.118
BRCA1	P38398-1.2	S1239D	Neutral	0.094
BRCA1	P38398-1.2	S1239E	Neutral	0.135
BRCA1	P38398-1.2	S1239F	Neutral	0.359
BRCA1	P38398-1.2	S1239G	Neutral	0.11
BRCA1	P38398-1.2	S1239H	Neutral	0.216
BRCA1	P38398-1.2	S1239I	Neutral	0.305
BRCA1	P38398-1.2	S1239K	Neutral	0.216
BRCA1	P38398-1.2	S1239L	Neutral	0.305
BRCA1	P38398-1.2	S1239M	Neutral	0.236
BRCA1	P38398-1.2	S1239N	Neutral	0.075
BRCA1	P38398-1.2	S1239P	Neutral	0.128
BRCA1	P38398-1.2	S1239Q	Neutral	0.149
BRCA1	P38398-1.2	S1239R	Neutral	0.346
BRCA1	P38398-1.2	S1239T	Neutral	0.071
BRCA1	P38398-1.2	S1239V	Neutral	0.225
BRCA1	P38398-1.2	S1239W	Pathogenic	0.598
BRCA1	P38398-1.2	S1239Y	Neutral	0.394
BRCA1	P38398-1.2	Q1240A	Neutral	0.121
BRCA1	P38398-1.2	Q1240C	Neutral	0.156
BRCA1	P38398-1.2	Q1240D	Neutral	0.053
BRCA1	P38398-1.2	Q1240E	Neutral	0.018
BRCA1	P38398-1.2	Q1240F	Neutral	0.135
BRCA1	P38398-1.2	Q1240G	Neutral	0.233
BRCA1	P38398-1.2	Q1240H	Neutral	0.036
BRCA1	P38398-1.2	Q1240I	Neutral	0.109
BRCA1	P38398-1.2	Q1240K	Neutral	0.036
BRCA1	P38398-1.2	Q1240L	Neutral	0.078
BRCA1	P38398-1.2	Q1240M	Neutral	0.04
BRCA1	P38398-1.2	Q1240N	Neutral	0.048
BRCA1	P38398-1.2	Q1240P	Neutral	0.076
BRCA1	P38398-1.2	Q1240R	Neutral	0.047
BRCA1	P38398-1.2	Q1240S	Neutral	0.078
BRCA1	P38398-1.2	Q1240T	Neutral	0.072
BRCA1	P38398-1.2	Q1240V	Neutral	0.077
BRCA1	P38398-1.2	Q1240W	Neutral	0.166
BRCA1	P38398-1.2	Q1240Y	Neutral	0.08
BRCA1	P38398-1.2	S1241A	Neutral	0.008
BRCA1	P38398-1.2	S1241C	Neutral	0.018
BRCA1	P38398-1.2	S1241D	Neutral	0.014
BRCA1	P38398-1.2	S1241E	Neutral	0.021
BRCA1	P38398-1.2	S1241F	Neutral	0.073
BRCA1	P38398-1.2	S1241G	Neutral	0.017
BRCA1	P38398-1.2	S1241H	Neutral	0.037
BRCA1	P38398-1.2	S1241I	Neutral	0.058
BRCA1	P38398-1.2	S1241K	Neutral	0.037
BRCA1	P38398-1.2	S1241L	Neutral	0.058
BRCA1	P38398-1.2	S1241M	Neutral	0.041
BRCA1	P38398-1.2	S1241N	Neutral	0.011
BRCA1	P38398-1.2	S1241P	Neutral	0.02
BRCA1	P38398-1.2	S1241Q	Neutral	0.024
BRCA1	P38398-1.2	S1241R	Neutral	0.069
BRCA1	P38398-1.2	S1241T	Neutral	0.011
BRCA1	P38398-1.2	S1241V	Neutral	0.039
BRCA1	P38398-1.2	S1241W	Neutral	0.172
BRCA1	P38398-1.2	S1241Y	Neutral	0.083
BRCA1	P38398-1.2	T1242A	Neutral	0.416
BRCA1	P38398-1.2	T1242C	Neutral	0.399
BRCA1	P38398-1.2	T1242D	Neutral	0.371
BRCA1	P38398-1.2	T1242E	Neutral	0.447
BRCA1	P38398-1.2	T1242F	Pathogenic	0.672
BRCA1	P38398-1.2	T1242G	Pathogenic	0.691
BRCA1	P38398-1.2	T1242H	Pathogenic	0.59
BRCA1	P38398-1.2	T1242I	Pathogenic	0.527
BRCA1	P38398-1.2	T1242K	Pathogenic	0.588
BRCA1	P38398-1.2	T1242L	Pathogenic	0.527
BRCA1	P38398-1.2	T1242M	Pathogenic	0.53
BRCA1	P38398-1.2	T1242N	Neutral	0.296
BRCA1	P38398-1.2	T1242P	Neutral	0.379
BRCA1	P38398-1.2	T1242Q	Neutral	0.476
BRCA1	P38398-1.2	T1242R	Pathogenic	0.656
BRCA1	P38398-1.2	T1242S	Neutral	0.301
BRCA1	P38398-1.2	T1242V	Neutral	0.339
BRCA1	P38398-1.2	T1242W	Pathogenic	0.791
BRCA1	P38398-1.2	T1242Y	Pathogenic	0.704
BRCA1	P38398-1.2	R1243A	Neutral	0.275
BRCA1	P38398-1.2	R1243C	Neutral	0.337
BRCA1	P38398-1.2	R1243D	Neutral	0.246
BRCA1	P38398-1.2	R1243E	Neutral	0.095
BRCA1	P38398-1.2	R1243F	Neutral	0.144
BRCA1	P38398-1.2	R1243G	Neutral	0.456
BRCA1	P38398-1.2	R1243H	Neutral	0.078
BRCA1	P38398-1.2	R1243I	Neutral	0.177
BRCA1	P38398-1.2	R1243K	Neutral	0.028
BRCA1	P38398-1.2	R1243L	Neutral	0.13
BRCA1	P38398-1.2	R1243M	Neutral	0.095
BRCA1	P38398-1.2	R1243N	Neutral	0.123
BRCA1	P38398-1.2	R1243P	Neutral	0.245
BRCA1	P38398-1.2	R1243Q	Neutral	0.061
BRCA1	P38398-1.2	R1243S	Neutral	0.25
BRCA1	P38398-1.2	R1243T	Neutral	0.176
BRCA1	P38398-1.2	R1243V	Neutral	0.249
BRCA1	P38398-1.2	R1243W	Neutral	0.149
BRCA1	P38398-1.2	R1243Y	Neutral	0.094
BRCA1	P38398-1.2	H1244A	Neutral	0.044
BRCA1	P38398-1.2	H1244C	Neutral	0.041
BRCA1	P38398-1.2	H1244D	Neutral	0.018
BRCA1	P38398-1.2	H1244E	Neutral	0.009
BRCA1	P38398-1.2	H1244F	Neutral	0.014
BRCA1	P38398-1.2	H1244G	Neutral	0.065
BRCA1	P38398-1.2	H1244I	Neutral	0.023
BRCA1	P38398-1.2	H1244K	Neutral	0.014
BRCA1	P38398-1.2	H1244L	Neutral	0.023
BRCA1	P38398-1.2	H1244M	Neutral	0.016
BRCA1	P38398-1.2	H1244N	Neutral	0.008
BRCA1	P38398-1.2	H1244P	Neutral	0.027
BRCA1	P38398-1.2	H1244Q	Neutral	0.008
BRCA1	P38398-1.2	H1244R	Neutral	0.013
BRCA1	P38398-1.2	H1244S	Neutral	0.027
BRCA1	P38398-1.2	H1244T	Neutral	0.025
BRCA1	P38398-1.2	H1244V	Neutral	0.027
BRCA1	P38398-1.2	H1244W	Neutral	0.037
BRCA1	P38398-1.2	H1244Y	Neutral	0.006
BRCA1	P38398-1.2	S1245A	Neutral	0.002
BRCA1	P38398-1.2	S1245C	Neutral	0.005
BRCA1	P38398-1.2	S1245D	Neutral	0.004
BRCA1	P38398-1.2	S1245E	Neutral	0.006
BRCA1	P38398-1.2	S1245F	Neutral	0.023
BRCA1	P38398-1.2	S1245G	Neutral	0.005
BRCA1	P38398-1.2	S1245H	Neutral	0.011
BRCA1	P38398-1.2	S1245I	Neutral	0.018
BRCA1	P38398-1.2	S1245K	Neutral	0.011
BRCA1	P38398-1.2	S1245L	Neutral	0.018
BRCA1	P38398-1.2	S1245M	Neutral	0.013
BRCA1	P38398-1.2	S1245N	Neutral	0.003
BRCA1	P38398-1.2	S1245P	Neutral	0.006
BRCA1	P38398-1.2	S1245Q	Neutral	0.007
BRCA1	P38398-1.2	S1245R	Neutral	0.021
BRCA1	P38398-1.2	S1245T	Neutral	0.003
BRCA1	P38398-1.2	S1245V	Neutral	0.012
BRCA1	P38398-1.2	S1245W	Neutral	0.058
BRCA1	P38398-1.2	S1245Y	Neutral	0.026
BRCA1	P38398-1.2	T1246A	Neutral	0.008
BRCA1	P38398-1.2	T1246C	Neutral	0.007
BRCA1	P38398-1.2	T1246D	Neutral	0.007
BRCA1	P38398-1.2	T1246E	Neutral	0.009
BRCA1	P38398-1.2	T1246F	Neutral	0.023
BRCA1	P38398-1.2	T1246G	Neutral	0.025
BRCA1	P38398-1.2	T1246H	Neutral	0.016
BRCA1	P38398-1.2	T1246I	Neutral	0.012
BRCA1	P38398-1.2	T1246K	Neutral	0.016
BRCA1	P38398-1.2	T1246L	Neutral	0.012
BRCA1	P38398-1.2	T1246M	Neutral	0.013
BRCA1	P38398-1.2	T1246N	Neutral	0.005
BRCA1	P38398-1.2	T1246P	Neutral	0.007
BRCA1	P38398-1.2	T1246Q	Neutral	0.01
BRCA1	P38398-1.2	T1246R	Neutral	0.021
BRCA1	P38398-1.2	T1246S	Neutral	0.005
BRCA1	P38398-1.2	T1246V	Neutral	0.006
BRCA1	P38398-1.2	T1246W	Neutral	0.041
BRCA1	P38398-1.2	T1246Y	Neutral	0.026
BRCA1	P38398-1.2	V1247A	Neutral	0.018
BRCA1	P38398-1.2	V1247C	Neutral	0.017
BRCA1	P38398-1.2	V1247D	Neutral	0.03
BRCA1	P38398-1.2	V1247E	Neutral	0.017
BRCA1	P38398-1.2	V1247F	Neutral	0.021
BRCA1	P38398-1.2	V1247G	Neutral	0.075
BRCA1	P38398-1.2	V1247H	Neutral	0.03
BRCA1	P38398-1.2	V1247I	Neutral	0.004
BRCA1	P38398-1.2	V1247K	Neutral	0.029
BRCA1	P38398-1.2	V1247L	Neutral	0.008
BRCA1	P38398-1.2	V1247M	Neutral	0.008
BRCA1	P38398-1.2	V1247N	Neutral	0.027
BRCA1	P38398-1.2	V1247P	Neutral	0.022
BRCA1	P38398-1.2	V1247Q	Neutral	0.019
BRCA1	P38398-1.2	V1247R	Neutral	0.055
BRCA1	P38398-1.2	V1247S	Neutral	0.031
BRCA1	P38398-1.2	V1247T	Neutral	0.01
BRCA1	P38398-1.2	V1247W	Neutral	0.077
BRCA1	P38398-1.2	V1247Y	Neutral	0.024
BRCA1	P38398-1.2	A1248C	Neutral	0.2
BRCA1	P38398-1.2	A1248D	Neutral	0.365
BRCA1	P38398-1.2	A1248E	Neutral	0.374
BRCA1	P38398-1.2	A1248F	Pathogenic	0.602
BRCA1	P38398-1.2	A1248G	Neutral	0.201
BRCA1	P38398-1.2	A1248H	Pathogenic	0.516
BRCA1	P38398-1.2	A1248I	Neutral	0.452
BRCA1	P38398-1.2	A1248K	Pathogenic	0.514
BRCA1	P38398-1.2	A1248L	Neutral	0.452
BRCA1	P38398-1.2	A1248M	Neutral	0.454
BRCA1	P38398-1.2	A1248N	Neutral	0.392
BRCA1	P38398-1.2	A1248P	Neutral	0.283
BRCA1	P38398-1.2	A1248Q	Neutral	0.402
BRCA1	P38398-1.2	A1248R	Pathogenic	0.585
BRCA1	P38398-1.2	A1248S	Neutral	0.116
BRCA1	P38398-1.2	A1248T	Neutral	0.228
BRCA1	P38398-1.2	A1248V	Neutral	0.275
BRCA1	P38398-1.2	A1248W	Pathogenic	0.801
BRCA1	P38398-1.2	A1248Y	Pathogenic	0.637
BRCA1	P38398-1.2	T1249A	Neutral	0.05
BRCA1	P38398-1.2	T1249C	Neutral	0.047
BRCA1	P38398-1.2	T1249D	Neutral	0.042
BRCA1	P38398-1.2	T1249E	Neutral	0.056
BRCA1	P38398-1.2	T1249F	Neutral	0.131
BRCA1	P38398-1.2	T1249G	Neutral	0.141
BRCA1	P38398-1.2	T1249H	Neutral	0.096
BRCA1	P38398-1.2	T1249I	Neutral	0.076
BRCA1	P38398-1.2	T1249K	Neutral	0.095
BRCA1	P38398-1.2	T1249L	Neutral	0.076
BRCA1	P38398-1.2	T1249M	Neutral	0.076
BRCA1	P38398-1.2	T1249N	Neutral	0.03
BRCA1	P38398-1.2	T1249P	Neutral	0.043
BRCA1	P38398-1.2	T1249Q	Neutral	0.063
BRCA1	P38398-1.2	T1249R	Neutral	0.123
BRCA1	P38398-1.2	T1249S	Neutral	0.031
BRCA1	P38398-1.2	T1249V	Neutral	0.036
BRCA1	P38398-1.2	T1249W	Neutral	0.217
BRCA1	P38398-1.2	T1249Y	Neutral	0.149
BRCA1	P38398-1.2	E1250A	Neutral	0.079
BRCA1	P38398-1.2	E1250C	Neutral	0.141
BRCA1	P38398-1.2	E1250D	Neutral	0.017
BRCA1	P38398-1.2	E1250F	Neutral	0.107
BRCA1	P38398-1.2	E1250G	Neutral	0.158
BRCA1	P38398-1.2	E1250H	Neutral	0.028
BRCA1	P38398-1.2	E1250I	Neutral	0.086
BRCA1	P38398-1.2	E1250K	Neutral	0.028
BRCA1	P38398-1.2	E1250L	Neutral	0.086
BRCA1	P38398-1.2	E1250M	Neutral	0.062
BRCA1	P38398-1.2	E1250N	Neutral	0.031
BRCA1	P38398-1.2	E1250P	Neutral	0.048
BRCA1	P38398-1.2	E1250Q	Neutral	0.013
BRCA1	P38398-1.2	E1250R	Neutral	0.053
BRCA1	P38398-1.2	E1250S	Neutral	0.05
BRCA1	P38398-1.2	E1250T	Neutral	0.046
BRCA1	P38398-1.2	E1250V	Neutral	0.049
BRCA1	P38398-1.2	E1250W	Neutral	0.182
BRCA1	P38398-1.2	E1250Y	Neutral	0.089
BRCA1	P38398-1.2	C1251A	Neutral	0.002
BRCA1	P38398-1.2	C1251D	Neutral	0.005
BRCA1	P38398-1.2	C1251E	Neutral	0.011
BRCA1	P38398-1.2	C1251F	Neutral	0.01
BRCA1	P38398-1.2	C1251G	Neutral	0.011
BRCA1	P38398-1.2	C1251H	Neutral	0.01
BRCA1	P38398-1.2	C1251I	Neutral	0.005
BRCA1	P38398-1.2	C1251K	Neutral	0.014
BRCA1	P38398-1.2	C1251L	Neutral	0.005
BRCA1	P38398-1.2	C1251M	Neutral	0.005
BRCA1	P38398-1.2	C1251N	Neutral	0.006
BRCA1	P38398-1.2	C1251P	Neutral	0.005
BRCA1	P38398-1.2	C1251Q	Neutral	0.009
BRCA1	P38398-1.2	C1251R	Neutral	0.018
BRCA1	P38398-1.2	C1251S	Neutral	0.003
BRCA1	P38398-1.2	C1251T	Neutral	0.003
BRCA1	P38398-1.2	C1251V	Neutral	0.004
BRCA1	P38398-1.2	C1251W	Neutral	0.018
BRCA1	P38398-1.2	C1251Y	Neutral	0.011
BRCA1	P38398-1.2	L1252A	Neutral	0.092
BRCA1	P38398-1.2	L1252C	Neutral	0.063
BRCA1	P38398-1.2	L1252D	Neutral	0.148
BRCA1	P38398-1.2	L1252E	Neutral	0.075
BRCA1	P38398-1.2	L1252F	Neutral	0.025
BRCA1	P38398-1.2	L1252G	Neutral	0.315
BRCA1	P38398-1.2	L1252H	Neutral	0.063
BRCA1	P38398-1.2	L1252I	Neutral	0.01
BRCA1	P38398-1.2	L1252K	Neutral	0.049
BRCA1	P38398-1.2	L1252M	Neutral	0.01
BRCA1	P38398-1.2	L1252N	Neutral	0.098
BRCA1	P38398-1.2	L1252P	Neutral	0.113
BRCA1	P38398-1.2	L1252Q	Neutral	0.049
BRCA1	P38398-1.2	L1252R	Neutral	0.064
BRCA1	P38398-1.2	L1252S	Neutral	0.113
BRCA1	P38398-1.2	L1252T	Neutral	0.054
BRCA1	P38398-1.2	L1252V	Neutral	0.021
BRCA1	P38398-1.2	L1252W	Neutral	0.091
BRCA1	P38398-1.2	L1252Y	Neutral	0.041
BRCA1	P38398-1.2	S1253A	Neutral	0.019
BRCA1	P38398-1.2	S1253C	Neutral	0.044
BRCA1	P38398-1.2	S1253D	Neutral	0.034
BRCA1	P38398-1.2	S1253E	Neutral	0.051
BRCA1	P38398-1.2	S1253F	Neutral	0.161
BRCA1	P38398-1.2	S1253G	Neutral	0.041
BRCA1	P38398-1.2	S1253H	Neutral	0.086
BRCA1	P38398-1.2	S1253I	Neutral	0.131
BRCA1	P38398-1.2	S1253K	Neutral	0.086
BRCA1	P38398-1.2	S1253L	Neutral	0.131
BRCA1	P38398-1.2	S1253M	Neutral	0.096
BRCA1	P38398-1.2	S1253N	Neutral	0.027
BRCA1	P38398-1.2	S1253P	Neutral	0.048
BRCA1	P38398-1.2	S1253Q	Neutral	0.057
BRCA1	P38398-1.2	S1253R	Neutral	0.153
BRCA1	P38398-1.2	S1253T	Neutral	0.025
BRCA1	P38398-1.2	S1253V	Neutral	0.091
BRCA1	P38398-1.2	S1253W	Neutral	0.338
BRCA1	P38398-1.2	S1253Y	Neutral	0.182
BRCA1	P38398-1.2	K1254A	Neutral	0.044
BRCA1	P38398-1.2	K1254C	Neutral	0.058
BRCA1	P38398-1.2	K1254D	Neutral	0.027
BRCA1	P38398-1.2	K1254E	Neutral	0.009
BRCA1	P38398-1.2	K1254F	Neutral	0.02
BRCA1	P38398-1.2	K1254G	Neutral	0.091
BRCA1	P38398-1.2	K1254H	Neutral	0.015
BRCA1	P38398-1.2	K1254I	Neutral	0.025
BRCA1	P38398-1.2	K1254L	Neutral	0.018
BRCA1	P38398-1.2	K1254M	Neutral	0.012
BRCA1	P38398-1.2	K1254N	Neutral	0.017
BRCA1	P38398-1.2	K1254P	Neutral	0.026
BRCA1	P38398-1.2	K1254Q	Neutral	0.008
BRCA1	P38398-1.2	K1254R	Neutral	0.005
BRCA1	P38398-1.2	K1254S	Neutral	0.027
BRCA1	P38398-1.2	K1254T	Neutral	0.025
BRCA1	P38398-1.2	K1254V	Neutral	0.027
BRCA1	P38398-1.2	K1254W	Neutral	0.036
BRCA1	P38398-1.2	K1254Y	Neutral	0.016
BRCA1	P38398-1.2	N1255A	Neutral	0.014
BRCA1	P38398-1.2	N1255C	Neutral	0.013
BRCA1	P38398-1.2	N1255D	Neutral	0.003
BRCA1	P38398-1.2	N1255E	Neutral	0.005
BRCA1	P38398-1.2	N1255F	Neutral	0.024
BRCA1	P38398-1.2	N1255G	Neutral	0.01
BRCA1	P38398-1.2	N1255H	Neutral	0.004
BRCA1	P38398-1.2	N1255I	Neutral	0.019
BRCA1	P38398-1.2	N1255K	Neutral	0.009
BRCA1	P38398-1.2	N1255L	Neutral	0.019
BRCA1	P38398-1.2	N1255M	Neutral	0.014
BRCA1	P38398-1.2	N1255P	Neutral	0.008
BRCA1	P38398-1.2	N1255Q	Neutral	0.005
BRCA1	P38398-1.2	N1255R	Neutral	0.012
BRCA1	P38398-1.2	N1255S	Neutral	0.004
BRCA1	P38398-1.2	N1255T	Neutral	0.004
BRCA1	P38398-1.2	N1255V	Neutral	0.013
BRCA1	P38398-1.2	N1255W	Neutral	0.062
BRCA1	P38398-1.2	N1255Y	Neutral	0.02
BRCA1	P38398-1.2	T1256A	Neutral	0.214
BRCA1	P38398-1.2	T1256C	Neutral	0.202
BRCA1	P38398-1.2	T1256D	Neutral	0.184
BRCA1	P38398-1.2	T1256E	Neutral	0.236
BRCA1	P38398-1.2	T1256F	Neutral	0.439
BRCA1	P38398-1.2	T1256G	Neutral	0.461
BRCA1	P38398-1.2	T1256H	Neutral	0.355
BRCA1	P38398-1.2	T1256I	Neutral	0.298
BRCA1	P38398-1.2	T1256K	Neutral	0.353
BRCA1	P38398-1.2	T1256L	Neutral	0.299
BRCA1	P38398-1.2	T1256M	Neutral	0.301
BRCA1	P38398-1.2	T1256N	Neutral	0.139
BRCA1	P38398-1.2	T1256P	Neutral	0.189
BRCA1	P38398-1.2	T1256Q	Neutral	0.258
BRCA1	P38398-1.2	T1256R	Neutral	0.422
BRCA1	P38398-1.2	T1256S	Neutral	0.142
BRCA1	P38398-1.2	T1256V	Neutral	0.164
BRCA1	P38398-1.2	T1256W	Pathogenic	0.591
BRCA1	P38398-1.2	T1256Y	Neutral	0.476
BRCA1	P38398-1.2	E1257A	Neutral	0.198
BRCA1	P38398-1.2	E1257C	Neutral	0.323
BRCA1	P38398-1.2	E1257D	Neutral	0.047
BRCA1	P38398-1.2	E1257F	Neutral	0.259
BRCA1	P38398-1.2	E1257G	Neutral	0.353
BRCA1	P38398-1.2	E1257H	Neutral	0.077
BRCA1	P38398-1.2	E1257I	Neutral	0.215
BRCA1	P38398-1.2	E1257K	Neutral	0.078
BRCA1	P38398-1.2	E1257L	Neutral	0.215
BRCA1	P38398-1.2	E1257M	Neutral	0.161
BRCA1	P38398-1.2	E1257N	Neutral	0.084
BRCA1	P38398-1.2	E1257P	Neutral	0.128
BRCA1	P38398-1.2	E1257Q	Neutral	0.036
BRCA1	P38398-1.2	E1257R	Neutral	0.14
BRCA1	P38398-1.2	E1257S	Neutral	0.131
BRCA1	P38398-1.2	E1257T	Neutral	0.122
BRCA1	P38398-1.2	E1257V	Neutral	0.131
BRCA1	P38398-1.2	E1257W	Neutral	0.392
BRCA1	P38398-1.2	E1257Y	Neutral	0.22
BRCA1	P38398-1.2	E1258A	Neutral	0.199
BRCA1	P38398-1.2	E1258C	Neutral	0.324
BRCA1	P38398-1.2	E1258D	Neutral	0.047
BRCA1	P38398-1.2	E1258F	Neutral	0.26
BRCA1	P38398-1.2	E1258G	Neutral	0.354
BRCA1	P38398-1.2	E1258H	Neutral	0.077
BRCA1	P38398-1.2	E1258I	Neutral	0.216
BRCA1	P38398-1.2	E1258K	Neutral	0.078
BRCA1	P38398-1.2	E1258L	Neutral	0.216
BRCA1	P38398-1.2	E1258M	Neutral	0.162
BRCA1	P38398-1.2	E1258N	Neutral	0.085
BRCA1	P38398-1.2	E1258P	Neutral	0.129
BRCA1	P38398-1.2	E1258Q	Neutral	0.036
BRCA1	P38398-1.2	E1258R	Neutral	0.14
BRCA1	P38398-1.2	E1258S	Neutral	0.132
BRCA1	P38398-1.2	E1258T	Neutral	0.123
BRCA1	P38398-1.2	E1258V	Neutral	0.131
BRCA1	P38398-1.2	E1258W	Neutral	0.393
BRCA1	P38398-1.2	E1258Y	Neutral	0.221
BRCA1	P38398-1.2	N1259A	Neutral	0.077
BRCA1	P38398-1.2	N1259C	Neutral	0.072
BRCA1	P38398-1.2	N1259D	Neutral	0.016
BRCA1	P38398-1.2	N1259E	Neutral	0.028
BRCA1	P38398-1.2	N1259F	Neutral	0.126
BRCA1	P38398-1.2	N1259G	Neutral	0.058
BRCA1	P38398-1.2	N1259H	Neutral	0.023
BRCA1	P38398-1.2	N1259I	Neutral	0.102
BRCA1	P38398-1.2	N1259K	Neutral	0.048
BRCA1	P38398-1.2	N1259L	Neutral	0.102
BRCA1	P38398-1.2	N1259M	Neutral	0.074
BRCA1	P38398-1.2	N1259P	Neutral	0.047
BRCA1	P38398-1.2	N1259Q	Neutral	0.031
BRCA1	P38398-1.2	N1259R	Neutral	0.063
BRCA1	P38398-1.2	N1259S	Neutral	0.024
BRCA1	P38398-1.2	N1259T	Neutral	0.022
BRCA1	P38398-1.2	N1259V	Neutral	0.07
BRCA1	P38398-1.2	N1259W	Neutral	0.278
BRCA1	P38398-1.2	N1259Y	Neutral	0.105
BRCA1	P38398-1.2	L1260A	Neutral	0.189
BRCA1	P38398-1.2	L1260C	Neutral	0.134
BRCA1	P38398-1.2	L1260D	Neutral	0.285
BRCA1	P38398-1.2	L1260E	Neutral	0.157
BRCA1	P38398-1.2	L1260F	Neutral	0.056
BRCA1	P38398-1.2	L1260G	Pathogenic	0.513
BRCA1	P38398-1.2	L1260H	Neutral	0.134
BRCA1	P38398-1.2	L1260I	Neutral	0.022
BRCA1	P38398-1.2	L1260K	Neutral	0.105
BRCA1	P38398-1.2	L1260M	Neutral	0.022
BRCA1	P38398-1.2	L1260N	Neutral	0.199
BRCA1	P38398-1.2	L1260P	Neutral	0.226
BRCA1	P38398-1.2	L1260Q	Neutral	0.105
BRCA1	P38398-1.2	L1260R	Neutral	0.136
BRCA1	P38398-1.2	L1260S	Neutral	0.226
BRCA1	P38398-1.2	L1260T	Neutral	0.116
BRCA1	P38398-1.2	L1260V	Neutral	0.047
BRCA1	P38398-1.2	L1260W	Neutral	0.186
BRCA1	P38398-1.2	L1260Y	Neutral	0.088
BRCA1	P38398-1.2	L1261A	Neutral	0.006
BRCA1	P38398-1.2	L1261C	Neutral	0.004
BRCA1	P38398-1.2	L1261D	Neutral	0.009
BRCA1	P38398-1.2	L1261E	Neutral	0.004
BRCA1	P38398-1.2	L1261F	Neutral	0.001
BRCA1	P38398-1.2	L1261G	Neutral	0.025
BRCA1	P38398-1.2	L1261H	Neutral	0.004
BRCA1	P38398-1.2	L1261I	Neutral	0.001
BRCA1	P38398-1.2	L1261K	Neutral	0.003
BRCA1	P38398-1.2	L1261M	Neutral	0.001
BRCA1	P38398-1.2	L1261N	Neutral	0.006
BRCA1	P38398-1.2	L1261P	Neutral	0.007
BRCA1	P38398-1.2	L1261Q	Neutral	0.003
BRCA1	P38398-1.2	L1261R	Neutral	0.004
BRCA1	P38398-1.2	L1261S	Neutral	0.007
BRCA1	P38398-1.2	L1261T	Neutral	0.003
BRCA1	P38398-1.2	L1261V	Neutral	0.001
BRCA1	P38398-1.2	L1261W	Neutral	0.005
BRCA1	P38398-1.2	L1261Y	Neutral	0.002
BRCA1	P38398-1.2	S1262A	Neutral	0.015
BRCA1	P38398-1.2	S1262C	Neutral	0.035
BRCA1	P38398-1.2	S1262D	Neutral	0.027
BRCA1	P38398-1.2	S1262E	Neutral	0.041
BRCA1	P38398-1.2	S1262F	Neutral	0.132
BRCA1	P38398-1.2	S1262G	Neutral	0.032
BRCA1	P38398-1.2	S1262H	Neutral	0.07
BRCA1	P38398-1.2	S1262I	Neutral	0.106
BRCA1	P38398-1.2	S1262K	Neutral	0.07
BRCA1	P38398-1.2	S1262L	Neutral	0.107
BRCA1	P38398-1.2	S1262M	Neutral	0.077
BRCA1	P38398-1.2	S1262N	Neutral	0.022
BRCA1	P38398-1.2	S1262P	Neutral	0.038
BRCA1	P38398-1.2	S1262Q	Neutral	0.045
BRCA1	P38398-1.2	S1262R	Neutral	0.125
BRCA1	P38398-1.2	S1262T	Neutral	0.02
BRCA1	P38398-1.2	S1262V	Neutral	0.073
BRCA1	P38398-1.2	S1262W	Neutral	0.288
BRCA1	P38398-1.2	S1262Y	Neutral	0.15
BRCA1	P38398-1.2	L1263A	Neutral	0.023
BRCA1	P38398-1.2	L1263C	Neutral	0.015
BRCA1	P38398-1.2	L1263D	Neutral	0.039
BRCA1	P38398-1.2	L1263E	Neutral	0.018
BRCA1	P38398-1.2	L1263F	Neutral	0.006
BRCA1	P38398-1.2	L1263G	Neutral	0.096
BRCA1	P38398-1.2	L1263H	Neutral	0.015
BRCA1	P38398-1.2	L1263I	Neutral	0.002
BRCA1	P38398-1.2	L1263K	Neutral	0.012
BRCA1	P38398-1.2	L1263M	Neutral	0.002
BRCA1	P38398-1.2	L1263N	Neutral	0.024
BRCA1	P38398-1.2	L1263P	Neutral	0.029
BRCA1	P38398-1.2	L1263Q	Neutral	0.012
BRCA1	P38398-1.2	L1263R	Neutral	0.016
BRCA1	P38398-1.2	L1263S	Neutral	0.029
BRCA1	P38398-1.2	L1263T	Neutral	0.013
BRCA1	P38398-1.2	L1263V	Neutral	0.005
BRCA1	P38398-1.2	L1263W	Neutral	0.023
BRCA1	P38398-1.2	L1263Y	Neutral	0.01
BRCA1	P38398-1.2	K1264A	Neutral	0.104
BRCA1	P38398-1.2	K1264C	Neutral	0.135
BRCA1	P38398-1.2	K1264D	Neutral	0.065
BRCA1	P38398-1.2	K1264E	Neutral	0.022
BRCA1	P38398-1.2	K1264F	Neutral	0.049
BRCA1	P38398-1.2	K1264G	Neutral	0.204
BRCA1	P38398-1.2	K1264H	Neutral	0.036
BRCA1	P38398-1.2	K1264I	Neutral	0.062
BRCA1	P38398-1.2	K1264L	Neutral	0.044
BRCA1	P38398-1.2	K1264M	Neutral	0.031
BRCA1	P38398-1.2	K1264N	Neutral	0.041
BRCA1	P38398-1.2	K1264P	Neutral	0.065
BRCA1	P38398-1.2	K1264Q	Neutral	0.02
BRCA1	P38398-1.2	K1264R	Neutral	0.012
BRCA1	P38398-1.2	K1264S	Neutral	0.066
BRCA1	P38398-1.2	K1264T	Neutral	0.061
BRCA1	P38398-1.2	K1264V	Neutral	0.066
BRCA1	P38398-1.2	K1264W	Neutral	0.087
BRCA1	P38398-1.2	K1264Y	Neutral	0.04
BRCA1	P38398-1.2	N1265A	Neutral	0.013
BRCA1	P38398-1.2	N1265C	Neutral	0.013
BRCA1	P38398-1.2	N1265D	Neutral	0.003
BRCA1	P38398-1.2	N1265E	Neutral	0.005
BRCA1	P38398-1.2	N1265F	Neutral	0.023
BRCA1	P38398-1.2	N1265G	Neutral	0.01
BRCA1	P38398-1.2	N1265H	Neutral	0.004
BRCA1	P38398-1.2	N1265I	Neutral	0.018
BRCA1	P38398-1.2	N1265K	Neutral	0.008
BRCA1	P38398-1.2	N1265L	Neutral	0.018
BRCA1	P38398-1.2	N1265M	Neutral	0.013
BRCA1	P38398-1.2	N1265P	Neutral	0.008
BRCA1	P38398-1.2	N1265Q	Neutral	0.005
BRCA1	P38398-1.2	N1265R	Neutral	0.011
BRCA1	P38398-1.2	N1265S	Neutral	0.004
BRCA1	P38398-1.2	N1265T	Neutral	0.004
BRCA1	P38398-1.2	N1265V	Neutral	0.012
BRCA1	P38398-1.2	N1265W	Neutral	0.06
BRCA1	P38398-1.2	N1265Y	Neutral	0.019
BRCA1	P38398-1.2	S1266A	Neutral	0.014
BRCA1	P38398-1.2	S1266C	Neutral	0.032
BRCA1	P38398-1.2	S1266D	Neutral	0.025
BRCA1	P38398-1.2	S1266E	Neutral	0.037
BRCA1	P38398-1.2	S1266F	Neutral	0.123
BRCA1	P38398-1.2	S1266G	Neutral	0.03
BRCA1	P38398-1.2	S1266H	Neutral	0.064
BRCA1	P38398-1.2	S1266I	Neutral	0.099
BRCA1	P38398-1.2	S1266K	Neutral	0.064
BRCA1	P38398-1.2	S1266L	Neutral	0.099
BRCA1	P38398-1.2	S1266M	Neutral	0.071
BRCA1	P38398-1.2	S1266N	Neutral	0.02
BRCA1	P38398-1.2	S1266P	Neutral	0.035
BRCA1	P38398-1.2	S1266Q	Neutral	0.042
BRCA1	P38398-1.2	S1266R	Neutral	0.116
BRCA1	P38398-1.2	S1266T	Neutral	0.019
BRCA1	P38398-1.2	S1266V	Neutral	0.068
BRCA1	P38398-1.2	S1266W	Neutral	0.271
BRCA1	P38398-1.2	S1266Y	Neutral	0.139
BRCA1	P38398-1.2	L1267A	Neutral	0.068
BRCA1	P38398-1.2	L1267C	Neutral	0.046
BRCA1	P38398-1.2	L1267D	Neutral	0.112
BRCA1	P38398-1.2	L1267E	Neutral	0.055
BRCA1	P38398-1.2	L1267F	Neutral	0.018
BRCA1	P38398-1.2	L1267G	Neutral	0.249
BRCA1	P38398-1.2	L1267H	Neutral	0.047
BRCA1	P38398-1.2	L1267I	Neutral	0.007
BRCA1	P38398-1.2	L1267K	Neutral	0.036
BRCA1	P38398-1.2	L1267M	Neutral	0.007
BRCA1	P38398-1.2	L1267N	Neutral	0.073
BRCA1	P38398-1.2	L1267P	Neutral	0.084
BRCA1	P38398-1.2	L1267Q	Neutral	0.035
BRCA1	P38398-1.2	L1267R	Neutral	0.047
BRCA1	P38398-1.2	L1267S	Neutral	0.084
BRCA1	P38398-1.2	L1267T	Neutral	0.04
BRCA1	P38398-1.2	L1267V	Neutral	0.015
BRCA1	P38398-1.2	L1267W	Neutral	0.067
BRCA1	P38398-1.2	L1267Y	Neutral	0.03
BRCA1	P38398-1.2	N1268A	Neutral	0.003
BRCA1	P38398-1.2	N1268C	Neutral	0.003
BRCA1	P38398-1.2	N1268D	Neutral	0.001
BRCA1	P38398-1.2	N1268E	Neutral	0.001
BRCA1	P38398-1.2	N1268F	Neutral	0.006
BRCA1	P38398-1.2	N1268G	Neutral	0.003
BRCA1	P38398-1.2	N1268H	Neutral	0.001
BRCA1	P38398-1.2	N1268I	Neutral	0.005
BRCA1	P38398-1.2	N1268K	Neutral	0.002
BRCA1	P38398-1.2	N1268L	Neutral	0.005
BRCA1	P38398-1.2	N1268M	Neutral	0.003
BRCA1	P38398-1.2	N1268P	Neutral	0.002
BRCA1	P38398-1.2	N1268Q	Neutral	0.001
BRCA1	P38398-1.2	N1268R	Neutral	0.003
BRCA1	P38398-1.2	N1268S	Neutral	0.001
BRCA1	P38398-1.2	N1268T	Neutral	0.001
BRCA1	P38398-1.2	N1268V	Neutral	0.003
BRCA1	P38398-1.2	N1268W	Neutral	0.016
BRCA1	P38398-1.2	N1268Y	Neutral	0.005
BRCA1	P38398-1.2	D1269A	Neutral	0.067
BRCA1	P38398-1.2	D1269C	Neutral	0.062
BRCA1	P38398-1.2	D1269E	Neutral	0.015
BRCA1	P38398-1.2	D1269F	Neutral	0.135
BRCA1	P38398-1.2	D1269G	Neutral	0.071
BRCA1	P38398-1.2	D1269H	Neutral	0.051
BRCA1	P38398-1.2	D1269I	Neutral	0.109
BRCA1	P38398-1.2	D1269K	Neutral	0.073
BRCA1	P38398-1.2	D1269L	Neutral	0.15
BRCA1	P38398-1.2	D1269M	Neutral	0.11
BRCA1	P38398-1.2	D1269N	Neutral	0.016
BRCA1	P38398-1.2	D1269P	Neutral	0.029
BRCA1	P38398-1.2	D1269Q	Neutral	0.033
BRCA1	P38398-1.2	D1269R	Neutral	0.131
BRCA1	P38398-1.2	D1269S	Neutral	0.029
BRCA1	P38398-1.2	D1269T	Neutral	0.03
BRCA1	P38398-1.2	D1269V	Neutral	0.075
BRCA1	P38398-1.2	D1269W	Neutral	0.293
BRCA1	P38398-1.2	D1269Y	Neutral	0.153
BRCA1	P38398-1.2	C1270A	Neutral	0.024
BRCA1	P38398-1.2	C1270D	Neutral	0.05
BRCA1	P38398-1.2	C1270E	Neutral	0.102
BRCA1	P38398-1.2	C1270F	Neutral	0.09
BRCA1	P38398-1.2	C1270G	Neutral	0.1
BRCA1	P38398-1.2	C1270H	Neutral	0.089
BRCA1	P38398-1.2	C1270I	Neutral	0.051
BRCA1	P38398-1.2	C1270K	Neutral	0.122
BRCA1	P38398-1.2	C1270L	Neutral	0.051
BRCA1	P38398-1.2	C1270M	Neutral	0.052
BRCA1	P38398-1.2	C1270N	Neutral	0.056
BRCA1	P38398-1.2	C1270P	Neutral	0.05
BRCA1	P38398-1.2	C1270Q	Neutral	0.081
BRCA1	P38398-1.2	C1270R	Neutral	0.157
BRCA1	P38398-1.2	C1270S	Neutral	0.03
BRCA1	P38398-1.2	C1270T	Neutral	0.026
BRCA1	P38398-1.2	C1270V	Neutral	0.034
BRCA1	P38398-1.2	C1270W	Neutral	0.154
BRCA1	P38398-1.2	C1270Y	Neutral	0.103
BRCA1	P38398-1.2	S1271A	Neutral	0.002
BRCA1	P38398-1.2	S1271C	Neutral	0.005
BRCA1	P38398-1.2	S1271D	Neutral	0.004
BRCA1	P38398-1.2	S1271E	Neutral	0.005
BRCA1	P38398-1.2	S1271F	Neutral	0.019
BRCA1	P38398-1.2	S1271G	Neutral	0.004
BRCA1	P38398-1.2	S1271H	Neutral	0.009
BRCA1	P38398-1.2	S1271I	Neutral	0.015
BRCA1	P38398-1.2	S1271K	Neutral	0.009
BRCA1	P38398-1.2	S1271L	Neutral	0.015
BRCA1	P38398-1.2	S1271M	Neutral	0.011
BRCA1	P38398-1.2	S1271N	Neutral	0.003
BRCA1	P38398-1.2	S1271P	Neutral	0.005
BRCA1	P38398-1.2	S1271Q	Neutral	0.006
BRCA1	P38398-1.2	S1271R	Neutral	0.018
BRCA1	P38398-1.2	S1271T	Neutral	0.003
BRCA1	P38398-1.2	S1271V	Neutral	0.01
BRCA1	P38398-1.2	S1271W	Neutral	0.049
BRCA1	P38398-1.2	S1271Y	Neutral	0.022
BRCA1	P38398-1.2	N1272A	Neutral	0.021
BRCA1	P38398-1.2	N1272C	Neutral	0.019
BRCA1	P38398-1.2	N1272D	Neutral	0.004
BRCA1	P38398-1.2	N1272E	Neutral	0.007
BRCA1	P38398-1.2	N1272F	Neutral	0.036
BRCA1	P38398-1.2	N1272G	Neutral	0.015
BRCA1	P38398-1.2	N1272H	Neutral	0.006
BRCA1	P38398-1.2	N1272I	Neutral	0.028
BRCA1	P38398-1.2	N1272K	Neutral	0.013
BRCA1	P38398-1.2	N1272L	Neutral	0.028
BRCA1	P38398-1.2	N1272M	Neutral	0.02
BRCA1	P38398-1.2	N1272P	Neutral	0.012
BRCA1	P38398-1.2	N1272Q	Neutral	0.008
BRCA1	P38398-1.2	N1272R	Neutral	0.017
BRCA1	P38398-1.2	N1272S	Neutral	0.006
BRCA1	P38398-1.2	N1272T	Neutral	0.006
BRCA1	P38398-1.2	N1272V	Neutral	0.019
BRCA1	P38398-1.2	N1272W	Neutral	0.09
BRCA1	P38398-1.2	N1272Y	Neutral	0.029
BRCA1	P38398-1.2	Q1273A	Neutral	0.101
BRCA1	P38398-1.2	Q1273C	Neutral	0.131
BRCA1	P38398-1.2	Q1273D	Neutral	0.044
BRCA1	P38398-1.2	Q1273E	Neutral	0.015
BRCA1	P38398-1.2	Q1273F	Neutral	0.113
BRCA1	P38398-1.2	Q1273G	Neutral	0.199
BRCA1	P38398-1.2	Q1273H	Neutral	0.029
BRCA1	P38398-1.2	Q1273I	Neutral	0.091
BRCA1	P38398-1.2	Q1273K	Neutral	0.03
BRCA1	P38398-1.2	Q1273L	Neutral	0.065
BRCA1	P38398-1.2	Q1273M	Neutral	0.033
BRCA1	P38398-1.2	Q1273N	Neutral	0.04
BRCA1	P38398-1.2	Q1273P	Neutral	0.063
BRCA1	P38398-1.2	Q1273R	Neutral	0.039
BRCA1	P38398-1.2	Q1273S	Neutral	0.065
BRCA1	P38398-1.2	Q1273T	Neutral	0.06
BRCA1	P38398-1.2	Q1273V	Neutral	0.064
BRCA1	P38398-1.2	Q1273W	Neutral	0.14
BRCA1	P38398-1.2	Q1273Y	Neutral	0.067
BRCA1	P38398-1.2	V1274A	Neutral	0.064
BRCA1	P38398-1.2	V1274C	Neutral	0.061
BRCA1	P38398-1.2	V1274D	Neutral	0.104
BRCA1	P38398-1.2	V1274E	Neutral	0.061
BRCA1	P38398-1.2	V1274F	Neutral	0.076
BRCA1	P38398-1.2	V1274G	Neutral	0.235
BRCA1	P38398-1.2	V1274H	Neutral	0.104
BRCA1	P38398-1.2	V1274I	Neutral	0.015
BRCA1	P38398-1.2	V1274K	Neutral	0.103
BRCA1	P38398-1.2	V1274L	Neutral	0.03
BRCA1	P38398-1.2	V1274M	Neutral	0.03
BRCA1	P38398-1.2	V1274N	Neutral	0.094
BRCA1	P38398-1.2	V1274P	Neutral	0.078
BRCA1	P38398-1.2	V1274Q	Neutral	0.068
BRCA1	P38398-1.2	V1274R	Neutral	0.18
BRCA1	P38398-1.2	V1274S	Neutral	0.109
BRCA1	P38398-1.2	V1274T	Neutral	0.037
BRCA1	P38398-1.2	V1274W	Neutral	0.239
BRCA1	P38398-1.2	V1274Y	Neutral	0.086
BRCA1	P38398-1.2	I1275A	Neutral	0.011
BRCA1	P38398-1.2	I1275C	Neutral	0.007
BRCA1	P38398-1.2	I1275D	Neutral	0.012
BRCA1	P38398-1.2	I1275E	Neutral	0.008
BRCA1	P38398-1.2	I1275F	Neutral	0.003
BRCA1	P38398-1.2	I1275G	Neutral	0.046
BRCA1	P38398-1.2	I1275H	Neutral	0.007
BRCA1	P38398-1.2	I1275K	Neutral	0.008
BRCA1	P38398-1.2	I1275L	Neutral	0.001
BRCA1	P38398-1.2	I1275M	Neutral	0.001
BRCA1	P38398-1.2	I1275N	Neutral	0.011
BRCA1	P38398-1.2	I1275P	Neutral	0.013
BRCA1	P38398-1.2	I1275Q	Neutral	0.008
BRCA1	P38398-1.2	I1275R	Neutral	0.01
BRCA1	P38398-1.2	I1275S	Neutral	0.013
BRCA1	P38398-1.2	I1275T	Neutral	0.006
BRCA1	P38398-1.2	I1275V	Neutral	0.001
BRCA1	P38398-1.2	I1275W	Neutral	0.015
BRCA1	P38398-1.2	I1275Y	Neutral	0.004
BRCA1	P38398-1.2	L1276A	Neutral	0.087
BRCA1	P38398-1.2	L1276C	Neutral	0.06
BRCA1	P38398-1.2	L1276D	Neutral	0.14
BRCA1	P38398-1.2	L1276E	Neutral	0.071
BRCA1	P38398-1.2	L1276F	Neutral	0.024
BRCA1	P38398-1.2	L1276G	Neutral	0.301
BRCA1	P38398-1.2	L1276H	Neutral	0.06
BRCA1	P38398-1.2	L1276I	Neutral	0.009
BRCA1	P38398-1.2	L1276K	Neutral	0.046
BRCA1	P38398-1.2	L1276M	Neutral	0.009
BRCA1	P38398-1.2	L1276N	Neutral	0.092
BRCA1	P38398-1.2	L1276P	Neutral	0.107
BRCA1	P38398-1.2	L1276Q	Neutral	0.046
BRCA1	P38398-1.2	L1276R	Neutral	0.06
BRCA1	P38398-1.2	L1276S	Neutral	0.107
BRCA1	P38398-1.2	L1276T	Neutral	0.051
BRCA1	P38398-1.2	L1276V	Neutral	0.02
BRCA1	P38398-1.2	L1276W	Neutral	0.085
BRCA1	P38398-1.2	L1276Y	Neutral	0.038
BRCA1	P38398-1.2	A1277C	Neutral	0.006
BRCA1	P38398-1.2	A1277D	Neutral	0.013
BRCA1	P38398-1.2	A1277E	Neutral	0.013
BRCA1	P38398-1.2	A1277F	Neutral	0.033
BRCA1	P38398-1.2	A1277G	Neutral	0.006
BRCA1	P38398-1.2	A1277H	Neutral	0.024
BRCA1	P38398-1.2	A1277I	Neutral	0.018
BRCA1	P38398-1.2	A1277K	Neutral	0.024
BRCA1	P38398-1.2	A1277L	Neutral	0.018
BRCA1	P38398-1.2	A1277M	Neutral	0.019
BRCA1	P38398-1.2	A1277N	Neutral	0.014
BRCA1	P38398-1.2	A1277P	Neutral	0.009
BRCA1	P38398-1.2	A1277Q	Neutral	0.015
BRCA1	P38398-1.2	A1277R	Neutral	0.031
BRCA1	P38398-1.2	A1277S	Neutral	0.003
BRCA1	P38398-1.2	A1277T	Neutral	0.007
BRCA1	P38398-1.2	A1277V	Neutral	0.009
BRCA1	P38398-1.2	A1277W	Neutral	0.084
BRCA1	P38398-1.2	A1277Y	Neutral	0.039
BRCA1	P38398-1.2	K1278A	Neutral	0.102
BRCA1	P38398-1.2	K1278C	Neutral	0.132
BRCA1	P38398-1.2	K1278D	Neutral	0.064
BRCA1	P38398-1.2	K1278E	Neutral	0.022
BRCA1	P38398-1.2	K1278F	Neutral	0.048
BRCA1	P38398-1.2	K1278G	Neutral	0.201
BRCA1	P38398-1.2	K1278H	Neutral	0.035
BRCA1	P38398-1.2	K1278I	Neutral	0.061
BRCA1	P38398-1.2	K1278L	Neutral	0.043
BRCA1	P38398-1.2	K1278M	Neutral	0.031
BRCA1	P38398-1.2	K1278N	Neutral	0.041
BRCA1	P38398-1.2	K1278P	Neutral	0.063
BRCA1	P38398-1.2	K1278Q	Neutral	0.019
BRCA1	P38398-1.2	K1278R	Neutral	0.011
BRCA1	P38398-1.2	K1278S	Neutral	0.065
BRCA1	P38398-1.2	K1278T	Neutral	0.06
BRCA1	P38398-1.2	K1278V	Neutral	0.065
BRCA1	P38398-1.2	K1278W	Neutral	0.085
BRCA1	P38398-1.2	K1278Y	Neutral	0.039
BRCA1	P38398-1.2	A1279C	Neutral	0.052
BRCA1	P38398-1.2	A1279D	Neutral	0.112
BRCA1	P38398-1.2	A1279E	Neutral	0.116
BRCA1	P38398-1.2	A1279F	Neutral	0.25
BRCA1	P38398-1.2	A1279G	Neutral	0.053
BRCA1	P38398-1.2	A1279H	Neutral	0.19
BRCA1	P38398-1.2	A1279I	Neutral	0.153
BRCA1	P38398-1.2	A1279K	Neutral	0.189
BRCA1	P38398-1.2	A1279L	Neutral	0.154
BRCA1	P38398-1.2	A1279M	Neutral	0.155
BRCA1	P38398-1.2	A1279N	Neutral	0.124
BRCA1	P38398-1.2	A1279P	Neutral	0.08
BRCA1	P38398-1.2	A1279Q	Neutral	0.129
BRCA1	P38398-1.2	A1279R	Neutral	0.237
BRCA1	P38398-1.2	A1279S	Neutral	0.028
BRCA1	P38398-1.2	A1279T	Neutral	0.061
BRCA1	P38398-1.2	A1279V	Neutral	0.077
BRCA1	P38398-1.2	A1279W	Neutral	0.47
BRCA1	P38398-1.2	A1279Y	Neutral	0.279
BRCA1	P38398-1.2	S1280A	Neutral	0.231
BRCA1	P38398-1.2	S1280C	Neutral	0.418
BRCA1	P38398-1.2	S1280D	Neutral	0.359
BRCA1	P38398-1.2	S1280E	Neutral	0.456
BRCA1	P38398-1.2	S1280F	Pathogenic	0.751
BRCA1	P38398-1.2	S1280G	Neutral	0.399
BRCA1	P38398-1.2	S1280H	Pathogenic	0.598
BRCA1	P38398-1.2	S1280I	Pathogenic	0.703
BRCA1	P38398-1.2	S1280K	Pathogenic	0.597
BRCA1	P38398-1.2	S1280L	Pathogenic	0.703
BRCA1	P38398-1.2	S1280M	Pathogenic	0.624
BRCA1	P38398-1.2	S1280N	Neutral	0.304
BRCA1	P38398-1.2	S1280P	Neutral	0.441
BRCA1	P38398-1.2	S1280Q	Neutral	0.486
BRCA1	P38398-1.2	S1280R	Pathogenic	0.74
BRCA1	P38398-1.2	S1280T	Neutral	0.291
BRCA1	P38398-1.2	S1280V	Pathogenic	0.611
BRCA1	P38398-1.2	S1280W	Pathogenic	0.889
BRCA1	P38398-1.2	S1280Y	Pathogenic	0.778
BRCA1	P38398-1.2	Q1281A	Neutral	0.422
BRCA1	P38398-1.2	Q1281C	Neutral	0.495
BRCA1	P38398-1.2	Q1281D	Neutral	0.23
BRCA1	P38398-1.2	Q1281E	Neutral	0.088
BRCA1	P38398-1.2	Q1281F	Neutral	0.452
BRCA1	P38398-1.2	Q1281G	Pathogenic	0.618
BRCA1	P38398-1.2	Q1281H	Neutral	0.164
BRCA1	P38398-1.2	Q1281I	Neutral	0.393
BRCA1	P38398-1.2	Q1281K	Neutral	0.165
BRCA1	P38398-1.2	Q1281L	Neutral	0.311
BRCA1	P38398-1.2	Q1281M	Neutral	0.18
BRCA1	P38398-1.2	Q1281N	Neutral	0.211
BRCA1	P38398-1.2	Q1281P	Neutral	0.303
BRCA1	P38398-1.2	Q1281R	Neutral	0.208
BRCA1	P38398-1.2	Q1281S	Neutral	0.309
BRCA1	P38398-1.2	Q1281T	Neutral	0.291
BRCA1	P38398-1.2	Q1281V	Neutral	0.308
BRCA1	P38398-1.2	Q1281W	Pathogenic	0.515
BRCA1	P38398-1.2	Q1281Y	Neutral	0.317
BRCA1	P38398-1.2	E1282A	Pathogenic	0.56
BRCA1	P38398-1.2	E1282C	Pathogenic	0.71
BRCA1	P38398-1.2	E1282D	Neutral	0.203
BRCA1	P38398-1.2	E1282F	Pathogenic	0.642
BRCA1	P38398-1.2	E1282G	Pathogenic	0.737
BRCA1	P38398-1.2	E1282H	Neutral	0.299
BRCA1	P38398-1.2	E1282I	Pathogenic	0.584
BRCA1	P38398-1.2	E1282K	Neutral	0.303
BRCA1	P38398-1.2	E1282L	Pathogenic	0.584
BRCA1	P38398-1.2	E1282M	Neutral	0.497
BRCA1	P38398-1.2	E1282N	Neutral	0.321
BRCA1	P38398-1.2	E1282P	Neutral	0.431
BRCA1	P38398-1.2	E1282Q	Neutral	0.159
BRCA1	P38398-1.2	E1282R	Neutral	0.455
BRCA1	P38398-1.2	E1282S	Neutral	0.438
BRCA1	P38398-1.2	E1282T	Neutral	0.417
BRCA1	P38398-1.2	E1282V	Neutral	0.436
BRCA1	P38398-1.2	E1282W	Pathogenic	0.768
BRCA1	P38398-1.2	E1282Y	Pathogenic	0.591
BRCA1	P38398-1.2	H1283A	Neutral	0.39
BRCA1	P38398-1.2	H1283C	Neutral	0.374
BRCA1	P38398-1.2	H1283D	Neutral	0.205
BRCA1	P38398-1.2	H1283E	Neutral	0.107
BRCA1	P38398-1.2	H1283F	Neutral	0.169
BRCA1	P38398-1.2	H1283G	Neutral	0.494
BRCA1	P38398-1.2	H1283I	Neutral	0.248
BRCA1	P38398-1.2	H1283K	Neutral	0.17
BRCA1	P38398-1.2	H1283L	Neutral	0.248
BRCA1	P38398-1.2	H1283M	Neutral	0.188
BRCA1	P38398-1.2	H1283N	Neutral	0.1
BRCA1	P38398-1.2	H1283P	Neutral	0.276
BRCA1	P38398-1.2	H1283Q	Neutral	0.098
BRCA1	P38398-1.2	H1283R	Neutral	0.16
BRCA1	P38398-1.2	H1283S	Neutral	0.28
BRCA1	P38398-1.2	H1283T	Neutral	0.265
BRCA1	P38398-1.2	H1283V	Neutral	0.28
BRCA1	P38398-1.2	H1283W	Neutral	0.351
BRCA1	P38398-1.2	H1283Y	Neutral	0.073
BRCA1	P38398-1.2	H1284A	Neutral	0.061
BRCA1	P38398-1.2	H1284C	Neutral	0.057
BRCA1	P38398-1.2	H1284D	Neutral	0.026
BRCA1	P38398-1.2	H1284E	Neutral	0.012
BRCA1	P38398-1.2	H1284F	Neutral	0.02
BRCA1	P38398-1.2	H1284G	Neutral	0.09
BRCA1	P38398-1.2	H1284I	Neutral	0.032
BRCA1	P38398-1.2	H1284K	Neutral	0.02
BRCA1	P38398-1.2	H1284L	Neutral	0.032
BRCA1	P38398-1.2	H1284M	Neutral	0.023
BRCA1	P38398-1.2	H1284N	Neutral	0.011
BRCA1	P38398-1.2	H1284P	Neutral	0.037
BRCA1	P38398-1.2	H1284Q	Neutral	0.011
BRCA1	P38398-1.2	H1284R	Neutral	0.019
BRCA1	P38398-1.2	H1284S	Neutral	0.038
BRCA1	P38398-1.2	H1284T	Neutral	0.035
BRCA1	P38398-1.2	H1284V	Neutral	0.038
BRCA1	P38398-1.2	H1284W	Neutral	0.052
BRCA1	P38398-1.2	H1284Y	Neutral	0.008
BRCA1	P38398-1.2	L1285A	Neutral	0.221
BRCA1	P38398-1.2	L1285C	Neutral	0.159
BRCA1	P38398-1.2	L1285D	Neutral	0.327
BRCA1	P38398-1.2	L1285E	Neutral	0.185
BRCA1	P38398-1.2	L1285F	Neutral	0.068
BRCA1	P38398-1.2	L1285G	Pathogenic	0.562
BRCA1	P38398-1.2	L1285H	Neutral	0.159
BRCA1	P38398-1.2	L1285I	Neutral	0.027
BRCA1	P38398-1.2	L1285K	Neutral	0.125
BRCA1	P38398-1.2	L1285M	Neutral	0.027
BRCA1	P38398-1.2	L1285N	Neutral	0.233
BRCA1	P38398-1.2	L1285P	Neutral	0.262
BRCA1	P38398-1.2	L1285Q	Neutral	0.125
BRCA1	P38398-1.2	L1285R	Neutral	0.161
BRCA1	P38398-1.2	L1285S	Neutral	0.262
BRCA1	P38398-1.2	L1285T	Neutral	0.137
BRCA1	P38398-1.2	L1285V	Neutral	0.057
BRCA1	P38398-1.2	L1285W	Neutral	0.218
BRCA1	P38398-1.2	L1285Y	Neutral	0.106
BRCA1	P38398-1.2	S1286A	Neutral	0.014
BRCA1	P38398-1.2	S1286C	Neutral	0.033
BRCA1	P38398-1.2	S1286D	Neutral	0.026
BRCA1	P38398-1.2	S1286E	Neutral	0.038
BRCA1	P38398-1.2	S1286F	Neutral	0.125
BRCA1	P38398-1.2	S1286G	Neutral	0.03
BRCA1	P38398-1.2	S1286H	Neutral	0.066
BRCA1	P38398-1.2	S1286I	Neutral	0.101
BRCA1	P38398-1.2	S1286K	Neutral	0.066
BRCA1	P38398-1.2	S1286L	Neutral	0.101
BRCA1	P38398-1.2	S1286M	Neutral	0.073
BRCA1	P38398-1.2	S1286N	Neutral	0.02
BRCA1	P38398-1.2	S1286P	Neutral	0.036
BRCA1	P38398-1.2	S1286Q	Neutral	0.043
BRCA1	P38398-1.2	S1286R	Neutral	0.119
BRCA1	P38398-1.2	S1286T	Neutral	0.019
BRCA1	P38398-1.2	S1286V	Neutral	0.069
BRCA1	P38398-1.2	S1286W	Neutral	0.275
BRCA1	P38398-1.2	S1286Y	Neutral	0.142
BRCA1	P38398-1.2	E1287A	Neutral	0.378
BRCA1	P38398-1.2	E1287C	Pathogenic	0.54
BRCA1	P38398-1.2	E1287D	Neutral	0.109
BRCA1	P38398-1.2	E1287F	Neutral	0.462
BRCA1	P38398-1.2	E1287G	Pathogenic	0.573
BRCA1	P38398-1.2	E1287H	Neutral	0.169
BRCA1	P38398-1.2	E1287I	Neutral	0.402
BRCA1	P38398-1.2	E1287K	Neutral	0.173
BRCA1	P38398-1.2	E1287L	Neutral	0.403
BRCA1	P38398-1.2	E1287M	Neutral	0.321
BRCA1	P38398-1.2	E1287N	Neutral	0.184
BRCA1	P38398-1.2	E1287P	Neutral	0.266
BRCA1	P38398-1.2	E1287Q	Neutral	0.083
BRCA1	P38398-1.2	E1287R	Neutral	0.286
BRCA1	P38398-1.2	E1287S	Neutral	0.272
BRCA1	P38398-1.2	E1287T	Neutral	0.255
BRCA1	P38398-1.2	E1287V	Neutral	0.27
BRCA1	P38398-1.2	E1287W	Pathogenic	0.613
BRCA1	P38398-1.2	E1287Y	Neutral	0.409
BRCA1	P38398-1.2	E1288A	Neutral	0.181
BRCA1	P38398-1.2	E1288C	Neutral	0.299
BRCA1	P38398-1.2	E1288D	Neutral	0.042
BRCA1	P38398-1.2	E1288F	Neutral	0.238
BRCA1	P38398-1.2	E1288G	Neutral	0.328
BRCA1	P38398-1.2	E1288H	Neutral	0.069
BRCA1	P38398-1.2	E1288I	Neutral	0.196
BRCA1	P38398-1.2	E1288K	Neutral	0.07
BRCA1	P38398-1.2	E1288L	Neutral	0.197
BRCA1	P38398-1.2	E1288M	Neutral	0.147
BRCA1	P38398-1.2	E1288N	Neutral	0.076
BRCA1	P38398-1.2	E1288P	Neutral	0.116
BRCA1	P38398-1.2	E1288Q	Neutral	0.032
BRCA1	P38398-1.2	E1288R	Neutral	0.127
BRCA1	P38398-1.2	E1288S	Neutral	0.119
BRCA1	P38398-1.2	E1288T	Neutral	0.111
BRCA1	P38398-1.2	E1288V	Neutral	0.119
BRCA1	P38398-1.2	E1288W	Neutral	0.366
BRCA1	P38398-1.2	E1288Y	Neutral	0.201
BRCA1	P38398-1.2	T1289A	Neutral	0.002
BRCA1	P38398-1.2	T1289C	Neutral	0.002
BRCA1	P38398-1.2	T1289D	Neutral	0.002
BRCA1	P38398-1.2	T1289E	Neutral	0.002
BRCA1	P38398-1.2	T1289F	Neutral	0.006
BRCA1	P38398-1.2	T1289G	Neutral	0.006
BRCA1	P38398-1.2	T1289H	Neutral	0.004
BRCA1	P38398-1.2	T1289I	Neutral	0.003
BRCA1	P38398-1.2	T1289K	Neutral	0.004
BRCA1	P38398-1.2	T1289L	Neutral	0.003
BRCA1	P38398-1.2	T1289M	Neutral	0.003
BRCA1	P38398-1.2	T1289N	Neutral	0.001
BRCA1	P38398-1.2	T1289P	Neutral	0.002
BRCA1	P38398-1.2	T1289Q	Neutral	0.003
BRCA1	P38398-1.2	T1289R	Neutral	0.005
BRCA1	P38398-1.2	T1289S	Neutral	0.001
BRCA1	P38398-1.2	T1289V	Neutral	0.001
BRCA1	P38398-1.2	T1289W	Neutral	0.01
BRCA1	P38398-1.2	T1289Y	Neutral	0.007
BRCA1	P38398-1.2	K1290A	Neutral	0.084
BRCA1	P38398-1.2	K1290C	Neutral	0.109
BRCA1	P38398-1.2	K1290D	Neutral	0.052
BRCA1	P38398-1.2	K1290E	Neutral	0.017
BRCA1	P38398-1.2	K1290F	Neutral	0.039
BRCA1	P38398-1.2	K1290G	Neutral	0.168
BRCA1	P38398-1.2	K1290H	Neutral	0.029
BRCA1	P38398-1.2	K1290I	Neutral	0.049
BRCA1	P38398-1.2	K1290L	Neutral	0.035
BRCA1	P38398-1.2	K1290M	Neutral	0.025
BRCA1	P38398-1.2	K1290N	Neutral	0.033
BRCA1	P38398-1.2	K1290P	Neutral	0.051
BRCA1	P38398-1.2	K1290Q	Neutral	0.015
BRCA1	P38398-1.2	K1290R	Neutral	0.009
BRCA1	P38398-1.2	K1290S	Neutral	0.053
BRCA1	P38398-1.2	K1290T	Neutral	0.049
BRCA1	P38398-1.2	K1290V	Neutral	0.053
BRCA1	P38398-1.2	K1290W	Neutral	0.07
BRCA1	P38398-1.2	K1290Y	Neutral	0.032
BRCA1	P38398-1.2	C1291A	Neutral	0.326
BRCA1	P38398-1.2	C1291D	Pathogenic	0.508
BRCA1	P38398-1.2	C1291E	Pathogenic	0.69
BRCA1	P38398-1.2	C1291F	Pathogenic	0.66
BRCA1	P38398-1.2	C1291G	Pathogenic	0.686
BRCA1	P38398-1.2	C1291H	Pathogenic	0.657
BRCA1	P38398-1.2	C1291I	Pathogenic	0.514
BRCA1	P38398-1.2	C1291K	Pathogenic	0.732
BRCA1	P38398-1.2	C1291L	Pathogenic	0.514
BRCA1	P38398-1.2	C1291M	Pathogenic	0.517
BRCA1	P38398-1.2	C1291N	Pathogenic	0.537
BRCA1	P38398-1.2	C1291P	Pathogenic	0.51
BRCA1	P38398-1.2	C1291Q	Pathogenic	0.635
BRCA1	P38398-1.2	C1291R	Pathogenic	0.785
BRCA1	P38398-1.2	C1291S	Neutral	0.377
BRCA1	P38398-1.2	C1291T	Neutral	0.347
BRCA1	P38398-1.2	C1291V	Neutral	0.412
BRCA1	P38398-1.2	C1291W	Pathogenic	0.782
BRCA1	P38398-1.2	C1291Y	Pathogenic	0.693
BRCA1	P38398-1.2	S1292A	Neutral	0.477
BRCA1	P38398-1.2	S1292C	Pathogenic	0.686
BRCA1	P38398-1.2	S1292D	Pathogenic	0.63
BRCA1	P38398-1.2	S1292E	Pathogenic	0.718
BRCA1	P38398-1.2	S1292F	Pathogenic	0.902
BRCA1	P38398-1.2	S1292G	Pathogenic	0.668
BRCA1	P38398-1.2	S1292H	Pathogenic	0.819
BRCA1	P38398-1.2	S1292I	Pathogenic	0.878
BRCA1	P38398-1.2	S1292K	Pathogenic	0.818
BRCA1	P38398-1.2	S1292L	Pathogenic	0.878
BRCA1	P38398-1.2	S1292M	Pathogenic	0.835
BRCA1	P38398-1.2	S1292N	Pathogenic	0.57
BRCA1	P38398-1.2	S1292P	Pathogenic	0.706
BRCA1	P38398-1.2	S1292Q	Pathogenic	0.741
BRCA1	P38398-1.2	S1292R	Pathogenic	0.896
BRCA1	P38398-1.2	S1292T	Pathogenic	0.555
BRCA1	P38398-1.2	S1292V	Pathogenic	0.827
BRCA1	P38398-1.2	S1292W	Pathogenic	0.961
BRCA1	P38398-1.2	S1292Y	Pathogenic	0.914
BRCA1	P38398-1.2	A1293C	Neutral	0.007
BRCA1	P38398-1.2	A1293D	Neutral	0.016
BRCA1	P38398-1.2	A1293E	Neutral	0.017
BRCA1	P38398-1.2	A1293F	Neutral	0.042
BRCA1	P38398-1.2	A1293G	Neutral	0.007
BRCA1	P38398-1.2	A1293H	Neutral	0.03
BRCA1	P38398-1.2	A1293I	Neutral	0.023
BRCA1	P38398-1.2	A1293K	Neutral	0.029
BRCA1	P38398-1.2	A1293L	Neutral	0.023
BRCA1	P38398-1.2	A1293M	Neutral	0.023
BRCA1	P38398-1.2	A1293N	Neutral	0.018
BRCA1	P38398-1.2	A1293P	Neutral	0.011
BRCA1	P38398-1.2	A1293Q	Neutral	0.019
BRCA1	P38398-1.2	A1293R	Neutral	0.039
BRCA1	P38398-1.2	A1293S	Neutral	0.004
BRCA1	P38398-1.2	A1293T	Neutral	0.008
BRCA1	P38398-1.2	A1293V	Neutral	0.011
BRCA1	P38398-1.2	A1293W	Neutral	0.103
BRCA1	P38398-1.2	A1293Y	Neutral	0.048
BRCA1	P38398-1.2	S1294A	Neutral	0.327
BRCA1	P38398-1.2	S1294C	Pathogenic	0.537
BRCA1	P38398-1.2	S1294D	Neutral	0.475
BRCA1	P38398-1.2	S1294E	Pathogenic	0.575
BRCA1	P38398-1.2	S1294F	Pathogenic	0.83
BRCA1	P38398-1.2	S1294G	Pathogenic	0.517
BRCA1	P38398-1.2	S1294H	Pathogenic	0.706
BRCA1	P38398-1.2	S1294I	Pathogenic	0.792
BRCA1	P38398-1.2	S1294K	Pathogenic	0.705
BRCA1	P38398-1.2	S1294L	Pathogenic	0.793
BRCA1	P38398-1.2	S1294M	Pathogenic	0.728
BRCA1	P38398-1.2	S1294N	Neutral	0.413
BRCA1	P38398-1.2	S1294P	Pathogenic	0.56
BRCA1	P38398-1.2	S1294Q	Pathogenic	0.604
BRCA1	P38398-1.2	S1294R	Pathogenic	0.821
BRCA1	P38398-1.2	S1294T	Neutral	0.399
BRCA1	P38398-1.2	S1294V	Pathogenic	0.717
BRCA1	P38398-1.2	S1294W	Pathogenic	0.928
BRCA1	P38398-1.2	S1294Y	Pathogenic	0.85
BRCA1	P38398-1.2	L1295A	Pathogenic	0.551
BRCA1	P38398-1.2	L1295C	Neutral	0.449
BRCA1	P38398-1.2	L1295D	Pathogenic	0.678
BRCA1	P38398-1.2	L1295E	Neutral	0.495
BRCA1	P38398-1.2	L1295F	Neutral	0.239
BRCA1	P38398-1.2	L1295G	Pathogenic	0.847
BRCA1	P38398-1.2	L1295H	Neutral	0.449
BRCA1	P38398-1.2	L1295I	Neutral	0.106
BRCA1	P38398-1.2	L1295K	Neutral	0.383
BRCA1	P38398-1.2	L1295M	Neutral	0.106
BRCA1	P38398-1.2	L1295N	Pathogenic	0.567
BRCA1	P38398-1.2	L1295P	Pathogenic	0.606
BRCA1	P38398-1.2	L1295Q	Neutral	0.381
BRCA1	P38398-1.2	L1295R	Neutral	0.453
BRCA1	P38398-1.2	L1295S	Pathogenic	0.606
BRCA1	P38398-1.2	L1295T	Neutral	0.408
BRCA1	P38398-1.2	L1295V	Neutral	0.206
BRCA1	P38398-1.2	L1295W	Pathogenic	0.546
BRCA1	P38398-1.2	L1295Y	Neutral	0.338
BRCA1	P38398-1.2	F1296A	Pathogenic	0.939
BRCA1	P38398-1.2	F1296C	Pathogenic	0.911
BRCA1	P38398-1.2	F1296D	Pathogenic	0.928
BRCA1	P38398-1.2	F1296E	Pathogenic	0.896
BRCA1	P38398-1.2	F1296G	Pathogenic	0.971
BRCA1	P38398-1.2	F1296H	Pathogenic	0.776
BRCA1	P38398-1.2	F1296I	Pathogenic	0.685
BRCA1	P38398-1.2	F1296K	Pathogenic	0.828
BRCA1	P38398-1.2	F1296L	Pathogenic	0.684
BRCA1	P38398-1.2	F1296M	Pathogenic	0.682
BRCA1	P38398-1.2	F1296N	Pathogenic	0.92
BRCA1	P38398-1.2	F1296P	Pathogenic	0.951
BRCA1	P38398-1.2	F1296Q	Pathogenic	0.886
BRCA1	P38398-1.2	F1296R	Pathogenic	0.865
BRCA1	P38398-1.2	F1296S	Pathogenic	0.931
BRCA1	P38398-1.2	F1296T	Pathogenic	0.897
BRCA1	P38398-1.2	F1296V	Pathogenic	0.825
BRCA1	P38398-1.2	F1296W	Pathogenic	0.686
BRCA1	P38398-1.2	F1296Y	Neutral	0.391
BRCA1	P38398-1.2	S1297A	Neutral	0.372
BRCA1	P38398-1.2	S1297C	Pathogenic	0.585
BRCA1	P38398-1.2	S1297D	Pathogenic	0.524
BRCA1	P38398-1.2	S1297E	Pathogenic	0.622
BRCA1	P38398-1.2	S1297F	Pathogenic	0.856
BRCA1	P38398-1.2	S1297G	Pathogenic	0.566
BRCA1	P38398-1.2	S1297H	Pathogenic	0.745
BRCA1	P38398-1.2	S1297I	Pathogenic	0.823
BRCA1	P38398-1.2	S1297K	Pathogenic	0.745
BRCA1	P38398-1.2	S1297L	Pathogenic	0.823
BRCA1	P38398-1.2	S1297M	Pathogenic	0.766
BRCA1	P38398-1.2	S1297N	Neutral	0.462
BRCA1	P38398-1.2	S1297P	Pathogenic	0.608
BRCA1	P38398-1.2	S1297Q	Pathogenic	0.65
BRCA1	P38398-1.2	S1297R	Pathogenic	0.849
BRCA1	P38398-1.2	S1297T	Neutral	0.447
BRCA1	P38398-1.2	S1297V	Pathogenic	0.755
BRCA1	P38398-1.2	S1297W	Pathogenic	0.94
BRCA1	P38398-1.2	S1297Y	Pathogenic	0.873
BRCA1	P38398-1.2	S1298A	Neutral	0.477
BRCA1	P38398-1.2	S1298C	Pathogenic	0.686
BRCA1	P38398-1.2	S1298D	Pathogenic	0.63
BRCA1	P38398-1.2	S1298E	Pathogenic	0.718
BRCA1	P38398-1.2	S1298F	Pathogenic	0.902
BRCA1	P38398-1.2	S1298G	Pathogenic	0.668
BRCA1	P38398-1.2	S1298H	Pathogenic	0.819
BRCA1	P38398-1.2	S1298I	Pathogenic	0.878
BRCA1	P38398-1.2	S1298K	Pathogenic	0.818
BRCA1	P38398-1.2	S1298L	Pathogenic	0.878
BRCA1	P38398-1.2	S1298M	Pathogenic	0.835
BRCA1	P38398-1.2	S1298N	Pathogenic	0.57
BRCA1	P38398-1.2	S1298P	Pathogenic	0.706
BRCA1	P38398-1.2	S1298Q	Pathogenic	0.741
BRCA1	P38398-1.2	S1298R	Pathogenic	0.896
BRCA1	P38398-1.2	S1298T	Pathogenic	0.555
BRCA1	P38398-1.2	S1298V	Pathogenic	0.827
BRCA1	P38398-1.2	S1298W	Pathogenic	0.961
BRCA1	P38398-1.2	S1298Y	Pathogenic	0.914
BRCA1	P38398-1.2	Q1299A	Pathogenic	0.595
BRCA1	P38398-1.2	Q1299C	Pathogenic	0.664
BRCA1	P38398-1.2	Q1299D	Neutral	0.375
BRCA1	P38398-1.2	Q1299E	Neutral	0.163
BRCA1	P38398-1.2	Q1299F	Pathogenic	0.624
BRCA1	P38398-1.2	Q1299G	Pathogenic	0.765
BRCA1	P38398-1.2	Q1299H	Neutral	0.283
BRCA1	P38398-1.2	Q1299I	Pathogenic	0.566
BRCA1	P38398-1.2	Q1299K	Neutral	0.284
BRCA1	P38398-1.2	Q1299L	Neutral	0.475
BRCA1	P38398-1.2	Q1299M	Neutral	0.306
BRCA1	P38398-1.2	Q1299N	Neutral	0.35
BRCA1	P38398-1.2	Q1299P	Neutral	0.467
BRCA1	P38398-1.2	Q1299R	Neutral	0.346
BRCA1	P38398-1.2	Q1299S	Neutral	0.474
BRCA1	P38398-1.2	Q1299T	Neutral	0.453
BRCA1	P38398-1.2	Q1299V	Neutral	0.472
BRCA1	P38398-1.2	Q1299W	Pathogenic	0.681
BRCA1	P38398-1.2	Q1299Y	Neutral	0.482
BRCA1	P38398-1.2	C1300A	Neutral	0.026
BRCA1	P38398-1.2	C1300D	Neutral	0.054
BRCA1	P38398-1.2	C1300E	Neutral	0.109
BRCA1	P38398-1.2	C1300F	Neutral	0.097
BRCA1	P38398-1.2	C1300G	Neutral	0.108
BRCA1	P38398-1.2	C1300H	Neutral	0.096
BRCA1	P38398-1.2	C1300I	Neutral	0.055
BRCA1	P38398-1.2	C1300K	Neutral	0.131
BRCA1	P38398-1.2	C1300L	Neutral	0.055
BRCA1	P38398-1.2	C1300M	Neutral	0.056
BRCA1	P38398-1.2	C1300N	Neutral	0.06
BRCA1	P38398-1.2	C1300P	Neutral	0.054
BRCA1	P38398-1.2	C1300Q	Neutral	0.088
BRCA1	P38398-1.2	C1300R	Neutral	0.168
BRCA1	P38398-1.2	C1300S	Neutral	0.032
BRCA1	P38398-1.2	C1300T	Neutral	0.029
BRCA1	P38398-1.2	C1300V	Neutral	0.037
BRCA1	P38398-1.2	C1300W	Neutral	0.165
BRCA1	P38398-1.2	C1300Y	Neutral	0.111
BRCA1	P38398-1.2	S1301A	Neutral	0.123
BRCA1	P38398-1.2	S1301C	Neutral	0.25
BRCA1	P38398-1.2	S1301D	Neutral	0.207
BRCA1	P38398-1.2	S1301E	Neutral	0.281
BRCA1	P38398-1.2	S1301F	Pathogenic	0.584
BRCA1	P38398-1.2	S1301G	Neutral	0.236
BRCA1	P38398-1.2	S1301H	Neutral	0.409
BRCA1	P38398-1.2	S1301I	Pathogenic	0.524
BRCA1	P38398-1.2	S1301K	Neutral	0.408
BRCA1	P38398-1.2	S1301L	Pathogenic	0.525
BRCA1	P38398-1.2	S1301M	Neutral	0.436
BRCA1	P38398-1.2	S1301N	Neutral	0.169
BRCA1	P38398-1.2	S1301P	Neutral	0.269
BRCA1	P38398-1.2	S1301Q	Neutral	0.305
BRCA1	P38398-1.2	S1301R	Pathogenic	0.57
BRCA1	P38398-1.2	S1301T	Neutral	0.16
BRCA1	P38398-1.2	S1301V	Neutral	0.422
BRCA1	P38398-1.2	S1301W	Pathogenic	0.789
BRCA1	P38398-1.2	S1301Y	Pathogenic	0.62
BRCA1	P38398-1.2	E1302A	Neutral	0.013
BRCA1	P38398-1.2	E1302C	Neutral	0.024
BRCA1	P38398-1.2	E1302D	Neutral	0.003
BRCA1	P38398-1.2	E1302F	Neutral	0.018
BRCA1	P38398-1.2	E1302G	Neutral	0.028
BRCA1	P38398-1.2	E1302H	Neutral	0.004
BRCA1	P38398-1.2	E1302I	Neutral	0.014
BRCA1	P38398-1.2	E1302K	Neutral	0.004
BRCA1	P38398-1.2	E1302L	Neutral	0.014
BRCA1	P38398-1.2	E1302M	Neutral	0.01
BRCA1	P38398-1.2	E1302N	Neutral	0.005
BRCA1	P38398-1.2	E1302P	Neutral	0.008
BRCA1	P38398-1.2	E1302Q	Neutral	0.002
BRCA1	P38398-1.2	E1302R	Neutral	0.008
BRCA1	P38398-1.2	E1302S	Neutral	0.008
BRCA1	P38398-1.2	E1302T	Neutral	0.007
BRCA1	P38398-1.2	E1302V	Neutral	0.008
BRCA1	P38398-1.2	E1302W	Neutral	0.033
BRCA1	P38398-1.2	E1302Y	Neutral	0.015
BRCA1	P38398-1.2	L1303A	Neutral	0.013
BRCA1	P38398-1.2	L1303C	Neutral	0.009
BRCA1	P38398-1.2	L1303D	Neutral	0.022
BRCA1	P38398-1.2	L1303E	Neutral	0.01
BRCA1	P38398-1.2	L1303F	Neutral	0.003
BRCA1	P38398-1.2	L1303G	Neutral	0.056
BRCA1	P38398-1.2	L1303H	Neutral	0.009
BRCA1	P38398-1.2	L1303I	Neutral	0.001
BRCA1	P38398-1.2	L1303K	Neutral	0.007
BRCA1	P38398-1.2	L1303M	Neutral	0.001
BRCA1	P38398-1.2	L1303N	Neutral	0.014
BRCA1	P38398-1.2	L1303P	Neutral	0.016
BRCA1	P38398-1.2	L1303Q	Neutral	0.007
BRCA1	P38398-1.2	L1303R	Neutral	0.009
BRCA1	P38398-1.2	L1303S	Neutral	0.016
BRCA1	P38398-1.2	L1303T	Neutral	0.007
BRCA1	P38398-1.2	L1303V	Neutral	0.003
BRCA1	P38398-1.2	L1303W	Neutral	0.013
BRCA1	P38398-1.2	L1303Y	Neutral	0.005
BRCA1	P38398-1.2	E1304A	Neutral	0.383
BRCA1	P38398-1.2	E1304C	Pathogenic	0.545
BRCA1	P38398-1.2	E1304D	Neutral	0.11
BRCA1	P38398-1.2	E1304F	Neutral	0.467
BRCA1	P38398-1.2	E1304G	Pathogenic	0.578
BRCA1	P38398-1.2	E1304H	Neutral	0.172
BRCA1	P38398-1.2	E1304I	Neutral	0.407
BRCA1	P38398-1.2	E1304K	Neutral	0.175
BRCA1	P38398-1.2	E1304L	Neutral	0.407
BRCA1	P38398-1.2	E1304M	Neutral	0.325
BRCA1	P38398-1.2	E1304N	Neutral	0.187
BRCA1	P38398-1.2	E1304P	Neutral	0.27
BRCA1	P38398-1.2	E1304Q	Neutral	0.085
BRCA1	P38398-1.2	E1304R	Neutral	0.29
BRCA1	P38398-1.2	E1304S	Neutral	0.275
BRCA1	P38398-1.2	E1304T	Neutral	0.258
BRCA1	P38398-1.2	E1304V	Neutral	0.274
BRCA1	P38398-1.2	E1304W	Pathogenic	0.618
BRCA1	P38398-1.2	E1304Y	Neutral	0.414
BRCA1	P38398-1.2	D1305A	Pathogenic	0.5
BRCA1	P38398-1.2	D1305C	Neutral	0.483
BRCA1	P38398-1.2	D1305E	Neutral	0.172
BRCA1	P38398-1.2	D1305F	Pathogenic	0.686
BRCA1	P38398-1.2	D1305G	Pathogenic	0.516
BRCA1	P38398-1.2	D1305H	Neutral	0.427
BRCA1	P38398-1.2	D1305I	Pathogenic	0.631
BRCA1	P38398-1.2	D1305K	Pathogenic	0.524
BRCA1	P38398-1.2	D1305L	Pathogenic	0.711
BRCA1	P38398-1.2	D1305M	Pathogenic	0.633
BRCA1	P38398-1.2	D1305N	Neutral	0.183
BRCA1	P38398-1.2	D1305P	Neutral	0.293
BRCA1	P38398-1.2	D1305Q	Neutral	0.323
BRCA1	P38398-1.2	D1305R	Pathogenic	0.679
BRCA1	P38398-1.2	D1305S	Neutral	0.299
BRCA1	P38398-1.2	D1305T	Neutral	0.299
BRCA1	P38398-1.2	D1305V	Pathogenic	0.531
BRCA1	P38398-1.2	D1305W	Pathogenic	0.853
BRCA1	P38398-1.2	D1305Y	Pathogenic	0.717
BRCA1	P38398-1.2	L1306A	Neutral	0.1
BRCA1	P38398-1.2	L1306C	Neutral	0.069
BRCA1	P38398-1.2	L1306D	Neutral	0.16
BRCA1	P38398-1.2	L1306E	Neutral	0.082
BRCA1	P38398-1.2	L1306F	Neutral	0.028
BRCA1	P38398-1.2	L1306G	Neutral	0.335
BRCA1	P38398-1.2	L1306H	Neutral	0.069
BRCA1	P38398-1.2	L1306I	Neutral	0.011
BRCA1	P38398-1.2	L1306K	Neutral	0.053
BRCA1	P38398-1.2	L1306M	Neutral	0.011
BRCA1	P38398-1.2	L1306N	Neutral	0.106
BRCA1	P38398-1.2	L1306P	Neutral	0.122
BRCA1	P38398-1.2	L1306Q	Neutral	0.053
BRCA1	P38398-1.2	L1306R	Neutral	0.07
BRCA1	P38398-1.2	L1306S	Neutral	0.122
BRCA1	P38398-1.2	L1306T	Neutral	0.059
BRCA1	P38398-1.2	L1306V	Neutral	0.023
BRCA1	P38398-1.2	L1306W	Neutral	0.098
BRCA1	P38398-1.2	L1306Y	Neutral	0.044
BRCA1	P38398-1.2	T1307A	Neutral	0.024
BRCA1	P38398-1.2	T1307C	Neutral	0.022
BRCA1	P38398-1.2	T1307D	Neutral	0.02
BRCA1	P38398-1.2	T1307E	Neutral	0.027
BRCA1	P38398-1.2	T1307F	Neutral	0.066
BRCA1	P38398-1.2	T1307G	Neutral	0.071
BRCA1	P38398-1.2	T1307H	Neutral	0.047
BRCA1	P38398-1.2	T1307I	Neutral	0.037
BRCA1	P38398-1.2	T1307K	Neutral	0.047
BRCA1	P38398-1.2	T1307L	Neutral	0.037
BRCA1	P38398-1.2	T1307M	Neutral	0.037
BRCA1	P38398-1.2	T1307N	Neutral	0.014
BRCA1	P38398-1.2	T1307P	Neutral	0.02
BRCA1	P38398-1.2	T1307Q	Neutral	0.03
BRCA1	P38398-1.2	T1307R	Neutral	0.061
BRCA1	P38398-1.2	T1307S	Neutral	0.015
BRCA1	P38398-1.2	T1307V	Neutral	0.017
BRCA1	P38398-1.2	T1307W	Neutral	0.115
BRCA1	P38398-1.2	T1307Y	Neutral	0.075
BRCA1	P38398-1.2	A1308C	Neutral	0.016
BRCA1	P38398-1.2	A1308D	Neutral	0.037
BRCA1	P38398-1.2	A1308E	Neutral	0.038
BRCA1	P38398-1.2	A1308F	Neutral	0.092
BRCA1	P38398-1.2	A1308G	Neutral	0.017
BRCA1	P38398-1.2	A1308H	Neutral	0.067
BRCA1	P38398-1.2	A1308I	Neutral	0.052
BRCA1	P38398-1.2	A1308K	Neutral	0.066
BRCA1	P38398-1.2	A1308L	Neutral	0.052
BRCA1	P38398-1.2	A1308M	Neutral	0.053
BRCA1	P38398-1.2	A1308N	Neutral	0.041
BRCA1	P38398-1.2	A1308P	Neutral	0.026
BRCA1	P38398-1.2	A1308Q	Neutral	0.043
BRCA1	P38398-1.2	A1308R	Neutral	0.086
BRCA1	P38398-1.2	A1308S	Neutral	0.009
BRCA1	P38398-1.2	A1308T	Neutral	0.019
BRCA1	P38398-1.2	A1308V	Neutral	0.025
BRCA1	P38398-1.2	A1308W	Neutral	0.212
BRCA1	P38398-1.2	A1308Y	Neutral	0.105
BRCA1	P38398-1.2	N1309A	Neutral	0.404
BRCA1	P38398-1.2	N1309C	Neutral	0.387
BRCA1	P38398-1.2	N1309D	Neutral	0.119
BRCA1	P38398-1.2	N1309E	Neutral	0.189
BRCA1	P38398-1.2	N1309F	Pathogenic	0.542
BRCA1	P38398-1.2	N1309G	Neutral	0.334
BRCA1	P38398-1.2	N1309H	Neutral	0.164
BRCA1	P38398-1.2	N1309I	Neutral	0.481
BRCA1	P38398-1.2	N1309K	Neutral	0.292
BRCA1	P38398-1.2	N1309L	Neutral	0.482
BRCA1	P38398-1.2	N1309M	Neutral	0.395
BRCA1	P38398-1.2	N1309P	Neutral	0.288
BRCA1	P38398-1.2	N1309Q	Neutral	0.206
BRCA1	P38398-1.2	N1309R	Neutral	0.355
BRCA1	P38398-1.2	N1309S	Neutral	0.167
BRCA1	P38398-1.2	N1309T	Neutral	0.155
BRCA1	P38398-1.2	N1309V	Neutral	0.381
BRCA1	P38398-1.2	N1309W	Pathogenic	0.759
BRCA1	P38398-1.2	N1309Y	Neutral	0.489
BRCA1	P38398-1.2	T1310A	Neutral	0.023
BRCA1	P38398-1.2	T1310C	Neutral	0.021
BRCA1	P38398-1.2	T1310D	Neutral	0.019
BRCA1	P38398-1.2	T1310E	Neutral	0.026
BRCA1	P38398-1.2	T1310F	Neutral	0.063
BRCA1	P38398-1.2	T1310G	Neutral	0.069
BRCA1	P38398-1.2	T1310H	Neutral	0.045
BRCA1	P38398-1.2	T1310I	Neutral	0.035
BRCA1	P38398-1.2	T1310K	Neutral	0.045
BRCA1	P38398-1.2	T1310L	Neutral	0.036
BRCA1	P38398-1.2	T1310M	Neutral	0.036
BRCA1	P38398-1.2	T1310N	Neutral	0.014
BRCA1	P38398-1.2	T1310P	Neutral	0.02
BRCA1	P38398-1.2	T1310Q	Neutral	0.029
BRCA1	P38398-1.2	T1310R	Neutral	0.059
BRCA1	P38398-1.2	T1310S	Neutral	0.014
BRCA1	P38398-1.2	T1310V	Neutral	0.017
BRCA1	P38398-1.2	T1310W	Neutral	0.111
BRCA1	P38398-1.2	T1310Y	Neutral	0.073
BRCA1	P38398-1.2	N1311A	Neutral	0.117
BRCA1	P38398-1.2	N1311C	Neutral	0.109
BRCA1	P38398-1.2	N1311D	Neutral	0.026
BRCA1	P38398-1.2	N1311E	Neutral	0.043
BRCA1	P38398-1.2	N1311F	Neutral	0.187
BRCA1	P38398-1.2	N1311G	Neutral	0.089
BRCA1	P38398-1.2	N1311H	Neutral	0.037
BRCA1	P38398-1.2	N1311I	Neutral	0.153
BRCA1	P38398-1.2	N1311K	Neutral	0.074
BRCA1	P38398-1.2	N1311L	Neutral	0.153
BRCA1	P38398-1.2	N1311M	Neutral	0.112
BRCA1	P38398-1.2	N1311P	Neutral	0.073
BRCA1	P38398-1.2	N1311Q	Neutral	0.048
BRCA1	P38398-1.2	N1311R	Neutral	0.097
BRCA1	P38398-1.2	N1311S	Neutral	0.038
BRCA1	P38398-1.2	N1311T	Neutral	0.035
BRCA1	P38398-1.2	N1311V	Neutral	0.107
BRCA1	P38398-1.2	N1311W	Neutral	0.38
BRCA1	P38398-1.2	N1311Y	Neutral	0.157
BRCA1	P38398-1.2	T1312A	Neutral	0.067
BRCA1	P38398-1.2	T1312C	Neutral	0.063
BRCA1	P38398-1.2	T1312D	Neutral	0.056
BRCA1	P38398-1.2	T1312E	Neutral	0.075
BRCA1	P38398-1.2	T1312F	Neutral	0.171
BRCA1	P38398-1.2	T1312G	Neutral	0.184
BRCA1	P38398-1.2	T1312H	Neutral	0.127
BRCA1	P38398-1.2	T1312I	Neutral	0.101
BRCA1	P38398-1.2	T1312K	Neutral	0.126
BRCA1	P38398-1.2	T1312L	Neutral	0.101
BRCA1	P38398-1.2	T1312M	Neutral	0.102
BRCA1	P38398-1.2	T1312N	Neutral	0.041
BRCA1	P38398-1.2	T1312P	Neutral	0.058
BRCA1	P38398-1.2	T1312Q	Neutral	0.084
BRCA1	P38398-1.2	T1312R	Neutral	0.161
BRCA1	P38398-1.2	T1312S	Neutral	0.042
BRCA1	P38398-1.2	T1312V	Neutral	0.049
BRCA1	P38398-1.2	T1312W	Neutral	0.275
BRCA1	P38398-1.2	T1312Y	Neutral	0.193
BRCA1	P38398-1.2	Q1313A	Pathogenic	0.765
BRCA1	P38398-1.2	Q1313C	Pathogenic	0.814
BRCA1	P38398-1.2	Q1313D	Pathogenic	0.57
BRCA1	P38398-1.2	Q1313E	Neutral	0.301
BRCA1	P38398-1.2	Q1313F	Pathogenic	0.786
BRCA1	P38398-1.2	Q1313G	Pathogenic	0.878
BRCA1	P38398-1.2	Q1313H	Neutral	0.466
BRCA1	P38398-1.2	Q1313I	Pathogenic	0.742
BRCA1	P38398-1.2	Q1313K	Neutral	0.467
BRCA1	P38398-1.2	Q1313L	Pathogenic	0.667
BRCA1	P38398-1.2	Q1313M	Neutral	0.494
BRCA1	P38398-1.2	Q1313N	Pathogenic	0.544
BRCA1	P38398-1.2	Q1313P	Pathogenic	0.66
BRCA1	P38398-1.2	Q1313R	Pathogenic	0.539
BRCA1	P38398-1.2	Q1313S	Pathogenic	0.666
BRCA1	P38398-1.2	Q1313T	Pathogenic	0.646
BRCA1	P38398-1.2	Q1313V	Pathogenic	0.664
BRCA1	P38398-1.2	Q1313W	Pathogenic	0.825
BRCA1	P38398-1.2	Q1313Y	Pathogenic	0.673
BRCA1	P38398-1.2	D1314A	Pathogenic	0.537
BRCA1	P38398-1.2	D1314C	Pathogenic	0.52
BRCA1	P38398-1.2	D1314E	Neutral	0.194
BRCA1	P38398-1.2	D1314F	Pathogenic	0.717
BRCA1	P38398-1.2	D1314G	Pathogenic	0.553
BRCA1	P38398-1.2	D1314H	Neutral	0.464
BRCA1	P38398-1.2	D1314I	Pathogenic	0.665
BRCA1	P38398-1.2	D1314K	Pathogenic	0.561
BRCA1	P38398-1.2	D1314L	Pathogenic	0.741
BRCA1	P38398-1.2	D1314M	Pathogenic	0.667
BRCA1	P38398-1.2	D1314N	Neutral	0.206
BRCA1	P38398-1.2	D1314P	Neutral	0.325
BRCA1	P38398-1.2	D1314Q	Neutral	0.357
BRCA1	P38398-1.2	D1314R	Pathogenic	0.711
BRCA1	P38398-1.2	D1314S	Neutral	0.331
BRCA1	P38398-1.2	D1314T	Neutral	0.331
BRCA1	P38398-1.2	D1314V	Pathogenic	0.568
BRCA1	P38398-1.2	D1314W	Pathogenic	0.871
BRCA1	P38398-1.2	D1314Y	Pathogenic	0.746
BRCA1	P38398-1.2	P1315A	Neutral	0.173
BRCA1	P38398-1.2	P1315C	Neutral	0.221
BRCA1	P38398-1.2	P1315D	Neutral	0.111
BRCA1	P38398-1.2	P1315E	Neutral	0.158
BRCA1	P38398-1.2	P1315F	Pathogenic	0.5
BRCA1	P38398-1.2	P1315G	Neutral	0.313
BRCA1	P38398-1.2	P1315H	Neutral	0.251
BRCA1	P38398-1.2	P1315I	Neutral	0.353
BRCA1	P38398-1.2	P1315K	Neutral	0.249
BRCA1	P38398-1.2	P1315L	Neutral	0.353
BRCA1	P38398-1.2	P1315M	Neutral	0.277
BRCA1	P38398-1.2	P1315N	Neutral	0.168
BRCA1	P38398-1.2	P1315Q	Neutral	0.174
BRCA1	P38398-1.2	P1315R	Neutral	0.389
BRCA1	P38398-1.2	P1315S	Neutral	0.154
BRCA1	P38398-1.2	P1315T	Neutral	0.118
BRCA1	P38398-1.2	P1315V	Neutral	0.201
BRCA1	P38398-1.2	P1315W	Pathogenic	0.649
BRCA1	P38398-1.2	P1315Y	Neutral	0.447
BRCA1	P38398-1.2	F1316A	Neutral	0.265
BRCA1	P38398-1.2	F1316C	Neutral	0.193
BRCA1	P38398-1.2	F1316D	Neutral	0.229
BRCA1	P38398-1.2	F1316E	Neutral	0.167
BRCA1	P38398-1.2	F1316G	Neutral	0.44
BRCA1	P38398-1.2	F1316H	Neutral	0.074
BRCA1	P38398-1.2	F1316I	Neutral	0.048
BRCA1	P38398-1.2	F1316K	Neutral	0.1
BRCA1	P38398-1.2	F1316L	Neutral	0.048
BRCA1	P38398-1.2	F1316M	Neutral	0.048
BRCA1	P38398-1.2	F1316N	Neutral	0.211
BRCA1	P38398-1.2	F1316P	Neutral	0.311
BRCA1	P38398-1.2	F1316Q	Neutral	0.153
BRCA1	P38398-1.2	F1316R	Neutral	0.13
BRCA1	P38398-1.2	F1316S	Neutral	0.238
BRCA1	P38398-1.2	F1316T	Neutral	0.168
BRCA1	P38398-1.2	F1316V	Neutral	0.099
BRCA1	P38398-1.2	F1316W	Neutral	0.048
BRCA1	P38398-1.2	F1316Y	Neutral	0.015
BRCA1	P38398-1.2	L1317A	Neutral	0.423
BRCA1	P38398-1.2	L1317C	Neutral	0.328
BRCA1	P38398-1.2	L1317D	Pathogenic	0.557
BRCA1	P38398-1.2	L1317E	Neutral	0.37
BRCA1	P38398-1.2	L1317F	Neutral	0.158
BRCA1	P38398-1.2	L1317G	Pathogenic	0.768
BRCA1	P38398-1.2	L1317H	Neutral	0.328
BRCA1	P38398-1.2	L1317I	Neutral	0.066
BRCA1	P38398-1.2	L1317K	Neutral	0.271
BRCA1	P38398-1.2	L1317M	Neutral	0.066
BRCA1	P38398-1.2	L1317N	Neutral	0.44
BRCA1	P38398-1.2	L1317P	Neutral	0.479
BRCA1	P38398-1.2	L1317Q	Neutral	0.269
BRCA1	P38398-1.2	L1317R	Neutral	0.331
BRCA1	P38398-1.2	L1317S	Neutral	0.479
BRCA1	P38398-1.2	L1317T	Neutral	0.292
BRCA1	P38398-1.2	L1317V	Neutral	0.134
BRCA1	P38398-1.2	L1317W	Neutral	0.419
BRCA1	P38398-1.2	L1317Y	Neutral	0.234
BRCA1	P38398-1.2	I1318A	Neutral	0.051
BRCA1	P38398-1.2	I1318C	Neutral	0.035
BRCA1	P38398-1.2	I1318D	Neutral	0.06
BRCA1	P38398-1.2	I1318E	Neutral	0.041
BRCA1	P38398-1.2	I1318F	Neutral	0.014
BRCA1	P38398-1.2	I1318G	Neutral	0.196
BRCA1	P38398-1.2	I1318H	Neutral	0.035
BRCA1	P38398-1.2	I1318K	Neutral	0.038
BRCA1	P38398-1.2	I1318L	Neutral	0.005
BRCA1	P38398-1.2	I1318M	Neutral	0.007
BRCA1	P38398-1.2	I1318N	Neutral	0.055
BRCA1	P38398-1.2	I1318P	Neutral	0.063
BRCA1	P38398-1.2	I1318Q	Neutral	0.038
BRCA1	P38398-1.2	I1318R	Neutral	0.05
BRCA1	P38398-1.2	I1318S	Neutral	0.063
BRCA1	P38398-1.2	I1318T	Neutral	0.029
BRCA1	P38398-1.2	I1318V	Neutral	0.005
BRCA1	P38398-1.2	I1318W	Neutral	0.071
BRCA1	P38398-1.2	I1318Y	Neutral	0.022
BRCA1	P38398-1.2	G1319A	Neutral	0.007
BRCA1	P38398-1.2	G1319C	Neutral	0.032
BRCA1	P38398-1.2	G1319D	Neutral	0.018
BRCA1	P38398-1.2	G1319E	Neutral	0.038
BRCA1	P38398-1.2	G1319F	Neutral	0.089
BRCA1	P38398-1.2	G1319H	Neutral	0.046
BRCA1	P38398-1.2	G1319I	Neutral	0.1
BRCA1	P38398-1.2	G1319K	Neutral	0.065
BRCA1	P38398-1.2	G1319L	Neutral	0.1
BRCA1	P38398-1.2	G1319M	Neutral	0.072
BRCA1	P38398-1.2	G1319N	Neutral	0.014
BRCA1	P38398-1.2	G1319P	Neutral	0.025
BRCA1	P38398-1.2	G1319Q	Neutral	0.042
BRCA1	P38398-1.2	G1319R	Neutral	0.085
BRCA1	P38398-1.2	G1319S	Neutral	0.009
BRCA1	P38398-1.2	G1319T	Neutral	0.027
BRCA1	P38398-1.2	G1319V	Neutral	0.048
BRCA1	P38398-1.2	G1319W	Neutral	0.112
BRCA1	P38398-1.2	G1319Y	Neutral	0.102
BRCA1	P38398-1.2	S1320A	Neutral	0.008
BRCA1	P38398-1.2	S1320C	Neutral	0.02
BRCA1	P38398-1.2	S1320D	Neutral	0.015
BRCA1	P38398-1.2	S1320E	Neutral	0.023
BRCA1	P38398-1.2	S1320F	Neutral	0.078
BRCA1	P38398-1.2	S1320G	Neutral	0.018
BRCA1	P38398-1.2	S1320H	Neutral	0.04
BRCA1	P38398-1.2	S1320I	Neutral	0.062
BRCA1	P38398-1.2	S1320K	Neutral	0.04
BRCA1	P38398-1.2	S1320L	Neutral	0.062
BRCA1	P38398-1.2	S1320M	Neutral	0.044
BRCA1	P38398-1.2	S1320N	Neutral	0.012
BRCA1	P38398-1.2	S1320P	Neutral	0.022
BRCA1	P38398-1.2	S1320Q	Neutral	0.026
BRCA1	P38398-1.2	S1320R	Neutral	0.074
BRCA1	P38398-1.2	S1320T	Neutral	0.011
BRCA1	P38398-1.2	S1320V	Neutral	0.042
BRCA1	P38398-1.2	S1320W	Neutral	0.184
BRCA1	P38398-1.2	S1320Y	Neutral	0.089
BRCA1	P38398-1.2	S1321A	Neutral	0.048
BRCA1	P38398-1.2	S1321C	Neutral	0.107
BRCA1	P38398-1.2	S1321D	Neutral	0.086
BRCA1	P38398-1.2	S1321E	Neutral	0.123
BRCA1	P38398-1.2	S1321F	Neutral	0.336
BRCA1	P38398-1.2	S1321G	Neutral	0.1
BRCA1	P38398-1.2	S1321H	Neutral	0.199
BRCA1	P38398-1.2	S1321I	Neutral	0.284
BRCA1	P38398-1.2	S1321K	Neutral	0.199
BRCA1	P38398-1.2	S1321L	Neutral	0.284
BRCA1	P38398-1.2	S1321M	Neutral	0.218
BRCA1	P38398-1.2	S1321N	Neutral	0.068
BRCA1	P38398-1.2	S1321P	Neutral	0.117
BRCA1	P38398-1.2	S1321Q	Neutral	0.137
BRCA1	P38398-1.2	S1321R	Neutral	0.323
BRCA1	P38398-1.2	S1321T	Neutral	0.064
BRCA1	P38398-1.2	S1321V	Neutral	0.208
BRCA1	P38398-1.2	S1321W	Pathogenic	0.574
BRCA1	P38398-1.2	S1321Y	Neutral	0.37
BRCA1	P38398-1.2	K1322A	Neutral	0.094
BRCA1	P38398-1.2	K1322C	Neutral	0.122
BRCA1	P38398-1.2	K1322D	Neutral	0.058
BRCA1	P38398-1.2	K1322E	Neutral	0.02
BRCA1	P38398-1.2	K1322F	Neutral	0.044
BRCA1	P38398-1.2	K1322G	Neutral	0.186
BRCA1	P38398-1.2	K1322H	Neutral	0.032
BRCA1	P38398-1.2	K1322I	Neutral	0.055
BRCA1	P38398-1.2	K1322L	Neutral	0.039
BRCA1	P38398-1.2	K1322M	Neutral	0.028
BRCA1	P38398-1.2	K1322N	Neutral	0.037
BRCA1	P38398-1.2	K1322P	Neutral	0.058
BRCA1	P38398-1.2	K1322Q	Neutral	0.017
BRCA1	P38398-1.2	K1322R	Neutral	0.01
BRCA1	P38398-1.2	K1322S	Neutral	0.059
BRCA1	P38398-1.2	K1322T	Neutral	0.055
BRCA1	P38398-1.2	K1322V	Neutral	0.059
BRCA1	P38398-1.2	K1322W	Neutral	0.078
BRCA1	P38398-1.2	K1322Y	Neutral	0.036
BRCA1	P38398-1.2	Q1323A	Neutral	0.176
BRCA1	P38398-1.2	Q1323C	Neutral	0.222
BRCA1	P38398-1.2	Q1323D	Neutral	0.08
BRCA1	P38398-1.2	Q1323E	Neutral	0.027
BRCA1	P38398-1.2	Q1323F	Neutral	0.194
BRCA1	P38398-1.2	Q1323G	Neutral	0.32
BRCA1	P38398-1.2	Q1323H	Neutral	0.054
BRCA1	P38398-1.2	Q1323I	Neutral	0.159
BRCA1	P38398-1.2	Q1323K	Neutral	0.054
BRCA1	P38398-1.2	Q1323L	Neutral	0.116
BRCA1	P38398-1.2	Q1323M	Neutral	0.06
BRCA1	P38398-1.2	Q1323N	Neutral	0.072
BRCA1	P38398-1.2	Q1323P	Neutral	0.113
BRCA1	P38398-1.2	Q1323R	Neutral	0.071
BRCA1	P38398-1.2	Q1323S	Neutral	0.116
BRCA1	P38398-1.2	Q1323T	Neutral	0.107
BRCA1	P38398-1.2	Q1323V	Neutral	0.115
BRCA1	P38398-1.2	Q1323W	Neutral	0.236
BRCA1	P38398-1.2	Q1323Y	Neutral	0.119
BRCA1	P38398-1.2	M1324A	Neutral	0.009
BRCA1	P38398-1.2	M1324C	Neutral	0.006
BRCA1	P38398-1.2	M1324D	Neutral	0.01
BRCA1	P38398-1.2	M1324E	Neutral	0.005
BRCA1	P38398-1.2	M1324F	Neutral	0.002
BRCA1	P38398-1.2	M1324G	Neutral	0.027
BRCA1	P38398-1.2	M1324H	Neutral	0.004
BRCA1	P38398-1.2	M1324I	Neutral	0.001
BRCA1	P38398-1.2	M1324K	Neutral	0.003
BRCA1	P38398-1.2	M1324L	Neutral	0.001
BRCA1	P38398-1.2	M1324N	Neutral	0.006
BRCA1	P38398-1.2	M1324P	Neutral	0.008
BRCA1	P38398-1.2	M1324Q	Neutral	0.002
BRCA1	P38398-1.2	M1324R	Neutral	0.004
BRCA1	P38398-1.2	M1324S	Neutral	0.008
BRCA1	P38398-1.2	M1324T	Neutral	0.005
BRCA1	P38398-1.2	M1324V	Neutral	0.002
BRCA1	P38398-1.2	M1324W	Neutral	0.006
BRCA1	P38398-1.2	M1324Y	Neutral	0.004
BRCA1	P38398-1.2	R1325A	Neutral	0.044
BRCA1	P38398-1.2	R1325C	Neutral	0.058
BRCA1	P38398-1.2	R1325D	Neutral	0.038
BRCA1	P38398-1.2	R1325E	Neutral	0.013
BRCA1	P38398-1.2	R1325F	Neutral	0.02
BRCA1	P38398-1.2	R1325G	Neutral	0.092
BRCA1	P38398-1.2	R1325H	Neutral	0.01
BRCA1	P38398-1.2	R1325I	Neutral	0.025
BRCA1	P38398-1.2	R1325K	Neutral	0.003
BRCA1	P38398-1.2	R1325L	Neutral	0.018
BRCA1	P38398-1.2	R1325M	Neutral	0.013
BRCA1	P38398-1.2	R1325N	Neutral	0.017
BRCA1	P38398-1.2	R1325P	Neutral	0.038
BRCA1	P38398-1.2	R1325Q	Neutral	0.008
BRCA1	P38398-1.2	R1325S	Neutral	0.039
BRCA1	P38398-1.2	R1325T	Neutral	0.025
BRCA1	P38398-1.2	R1325V	Neutral	0.039
BRCA1	P38398-1.2	R1325W	Neutral	0.021
BRCA1	P38398-1.2	R1325Y	Neutral	0.012
BRCA1	P38398-1.2	H1326A	Neutral	0.075
BRCA1	P38398-1.2	H1326C	Neutral	0.07
BRCA1	P38398-1.2	H1326D	Neutral	0.032
BRCA1	P38398-1.2	H1326E	Neutral	0.015
BRCA1	P38398-1.2	H1326F	Neutral	0.025
BRCA1	P38398-1.2	H1326G	Neutral	0.11
BRCA1	P38398-1.2	H1326I	Neutral	0.04
BRCA1	P38398-1.2	H1326K	Neutral	0.025
BRCA1	P38398-1.2	H1326L	Neutral	0.04
BRCA1	P38398-1.2	H1326M	Neutral	0.028
BRCA1	P38398-1.2	H1326N	Neutral	0.014
BRCA1	P38398-1.2	H1326P	Neutral	0.046
BRCA1	P38398-1.2	H1326Q	Neutral	0.014
BRCA1	P38398-1.2	H1326R	Neutral	0.024
BRCA1	P38398-1.2	H1326S	Neutral	0.047
BRCA1	P38398-1.2	H1326T	Neutral	0.044
BRCA1	P38398-1.2	H1326V	Neutral	0.047
BRCA1	P38398-1.2	H1326W	Neutral	0.064
BRCA1	P38398-1.2	H1326Y	Neutral	0.01
BRCA1	P38398-1.2	Q1327A	Neutral	0.043
BRCA1	P38398-1.2	Q1327C	Neutral	0.057
BRCA1	P38398-1.2	Q1327D	Neutral	0.018
BRCA1	P38398-1.2	Q1327E	Neutral	0.006
BRCA1	P38398-1.2	Q1327F	Neutral	0.048
BRCA1	P38398-1.2	Q1327G	Neutral	0.09
BRCA1	P38398-1.2	Q1327H	Neutral	0.012
BRCA1	P38398-1.2	Q1327I	Neutral	0.038
BRCA1	P38398-1.2	Q1327K	Neutral	0.012
BRCA1	P38398-1.2	Q1327L	Neutral	0.027
BRCA1	P38398-1.2	Q1327M	Neutral	0.013
BRCA1	P38398-1.2	Q1327N	Neutral	0.016
BRCA1	P38398-1.2	Q1327P	Neutral	0.026
BRCA1	P38398-1.2	Q1327R	Neutral	0.016
BRCA1	P38398-1.2	Q1327S	Neutral	0.027
BRCA1	P38398-1.2	Q1327T	Neutral	0.025
BRCA1	P38398-1.2	Q1327V	Neutral	0.027
BRCA1	P38398-1.2	Q1327W	Neutral	0.061
BRCA1	P38398-1.2	Q1327Y	Neutral	0.028
BRCA1	P38398-1.2	S1328A	Neutral	0.071
BRCA1	P38398-1.2	S1328C	Neutral	0.155
BRCA1	P38398-1.2	S1328D	Neutral	0.126
BRCA1	P38398-1.2	S1328E	Neutral	0.177
BRCA1	P38398-1.2	S1328F	Neutral	0.436
BRCA1	P38398-1.2	S1328G	Neutral	0.145
BRCA1	P38398-1.2	S1328H	Neutral	0.276
BRCA1	P38398-1.2	S1328I	Neutral	0.377
BRCA1	P38398-1.2	S1328K	Neutral	0.275
BRCA1	P38398-1.2	S1328L	Neutral	0.378
BRCA1	P38398-1.2	S1328M	Neutral	0.299
BRCA1	P38398-1.2	S1328N	Neutral	0.101
BRCA1	P38398-1.2	S1328P	Neutral	0.168
BRCA1	P38398-1.2	S1328Q	Neutral	0.195
BRCA1	P38398-1.2	S1328R	Neutral	0.422
BRCA1	P38398-1.2	S1328T	Neutral	0.095
BRCA1	P38398-1.2	S1328V	Neutral	0.287
BRCA1	P38398-1.2	S1328W	Pathogenic	0.673
BRCA1	P38398-1.2	S1328Y	Neutral	0.473
BRCA1	P38398-1.2	E1329A	Neutral	0.093
BRCA1	P38398-1.2	E1329C	Neutral	0.165
BRCA1	P38398-1.2	E1329D	Neutral	0.02
BRCA1	P38398-1.2	E1329F	Neutral	0.126
BRCA1	P38398-1.2	E1329G	Neutral	0.184
BRCA1	P38398-1.2	E1329H	Neutral	0.033
BRCA1	P38398-1.2	E1329I	Neutral	0.102
BRCA1	P38398-1.2	E1329K	Neutral	0.034
BRCA1	P38398-1.2	E1329L	Neutral	0.102
BRCA1	P38398-1.2	E1329M	Neutral	0.074
BRCA1	P38398-1.2	E1329N	Neutral	0.037
BRCA1	P38398-1.2	E1329P	Neutral	0.057
BRCA1	P38398-1.2	E1329Q	Neutral	0.015
BRCA1	P38398-1.2	E1329R	Neutral	0.063
BRCA1	P38398-1.2	E1329S	Neutral	0.059
BRCA1	P38398-1.2	E1329T	Neutral	0.054
BRCA1	P38398-1.2	E1329V	Neutral	0.059
BRCA1	P38398-1.2	E1329W	Neutral	0.211
BRCA1	P38398-1.2	E1329Y	Neutral	0.104
BRCA1	P38398-1.2	S1330A	Neutral	0.001
BRCA1	P38398-1.2	S1330C	Neutral	0.002
BRCA1	P38398-1.2	S1330D	Neutral	0.002
BRCA1	P38398-1.2	S1330E	Neutral	0.003
BRCA1	P38398-1.2	S1330F	Neutral	0.01
BRCA1	P38398-1.2	S1330G	Neutral	0.002
BRCA1	P38398-1.2	S1330H	Neutral	0.005
BRCA1	P38398-1.2	S1330I	Neutral	0.008
BRCA1	P38398-1.2	S1330K	Neutral	0.005
BRCA1	P38398-1.2	S1330L	Neutral	0.008
BRCA1	P38398-1.2	S1330M	Neutral	0.006
BRCA1	P38398-1.2	S1330N	Neutral	0.001
BRCA1	P38398-1.2	S1330P	Neutral	0.003
BRCA1	P38398-1.2	S1330Q	Neutral	0.003
BRCA1	P38398-1.2	S1330R	Neutral	0.009
BRCA1	P38398-1.2	S1330T	Neutral	0.001
BRCA1	P38398-1.2	S1330V	Neutral	0.005
BRCA1	P38398-1.2	S1330W	Neutral	0.026
BRCA1	P38398-1.2	S1330Y	Neutral	0.012
BRCA1	P38398-1.2	Q1331A	Neutral	0.091
BRCA1	P38398-1.2	Q1331C	Neutral	0.118
BRCA1	P38398-1.2	Q1331D	Neutral	0.039
BRCA1	P38398-1.2	Q1331E	Neutral	0.013
BRCA1	P38398-1.2	Q1331F	Neutral	0.101
BRCA1	P38398-1.2	Q1331G	Neutral	0.181
BRCA1	P38398-1.2	Q1331H	Neutral	0.026
BRCA1	P38398-1.2	Q1331I	Neutral	0.081
BRCA1	P38398-1.2	Q1331K	Neutral	0.026
BRCA1	P38398-1.2	Q1331L	Neutral	0.058
BRCA1	P38398-1.2	Q1331M	Neutral	0.029
BRCA1	P38398-1.2	Q1331N	Neutral	0.035
BRCA1	P38398-1.2	Q1331P	Neutral	0.056
BRCA1	P38398-1.2	Q1331R	Neutral	0.035
BRCA1	P38398-1.2	Q1331S	Neutral	0.058
BRCA1	P38398-1.2	Q1331T	Neutral	0.053
BRCA1	P38398-1.2	Q1331V	Neutral	0.057
BRCA1	P38398-1.2	Q1331W	Neutral	0.127
BRCA1	P38398-1.2	Q1331Y	Neutral	0.06
BRCA1	P38398-1.2	G1332A	Neutral	0.016
BRCA1	P38398-1.2	G1332C	Neutral	0.067
BRCA1	P38398-1.2	G1332D	Neutral	0.037
BRCA1	P38398-1.2	G1332E	Neutral	0.077
BRCA1	P38398-1.2	G1332F	Neutral	0.173
BRCA1	P38398-1.2	G1332H	Neutral	0.093
BRCA1	P38398-1.2	G1332I	Neutral	0.19
BRCA1	P38398-1.2	G1332K	Neutral	0.128
BRCA1	P38398-1.2	G1332L	Neutral	0.191
BRCA1	P38398-1.2	G1332M	Neutral	0.142
BRCA1	P38398-1.2	G1332N	Neutral	0.029
BRCA1	P38398-1.2	G1332P	Neutral	0.052
BRCA1	P38398-1.2	G1332Q	Neutral	0.086
BRCA1	P38398-1.2	G1332R	Neutral	0.164
BRCA1	P38398-1.2	G1332S	Neutral	0.018
BRCA1	P38398-1.2	G1332T	Neutral	0.056
BRCA1	P38398-1.2	G1332V	Neutral	0.098
BRCA1	P38398-1.2	G1332W	Neutral	0.211
BRCA1	P38398-1.2	G1332Y	Neutral	0.195
BRCA1	P38398-1.2	V1333A	Neutral	0.027
BRCA1	P38398-1.2	V1333C	Neutral	0.025
BRCA1	P38398-1.2	V1333D	Neutral	0.045
BRCA1	P38398-1.2	V1333E	Neutral	0.025
BRCA1	P38398-1.2	V1333F	Neutral	0.032
BRCA1	P38398-1.2	V1333G	Neutral	0.11
BRCA1	P38398-1.2	V1333H	Neutral	0.045
BRCA1	P38398-1.2	V1333I	Neutral	0.006
BRCA1	P38398-1.2	V1333K	Neutral	0.044
BRCA1	P38398-1.2	V1333L	Neutral	0.012
BRCA1	P38398-1.2	V1333M	Neutral	0.013
BRCA1	P38398-1.2	V1333N	Neutral	0.04
BRCA1	P38398-1.2	V1333P	Neutral	0.033
BRCA1	P38398-1.2	V1333Q	Neutral	0.029
BRCA1	P38398-1.2	V1333R	Neutral	0.082
BRCA1	P38398-1.2	V1333S	Neutral	0.047
BRCA1	P38398-1.2	V1333T	Neutral	0.015
BRCA1	P38398-1.2	V1333W	Neutral	0.112
BRCA1	P38398-1.2	V1333Y	Neutral	0.037
BRCA1	P38398-1.2	G1334A	Neutral	0.012
BRCA1	P38398-1.2	G1334C	Neutral	0.051
BRCA1	P38398-1.2	G1334D	Neutral	0.028
BRCA1	P38398-1.2	G1334E	Neutral	0.059
BRCA1	P38398-1.2	G1334F	Neutral	0.135
BRCA1	P38398-1.2	G1334H	Neutral	0.071
BRCA1	P38398-1.2	G1334I	Neutral	0.149
BRCA1	P38398-1.2	G1334K	Neutral	0.099
BRCA1	P38398-1.2	G1334L	Neutral	0.15
BRCA1	P38398-1.2	G1334M	Neutral	0.11
BRCA1	P38398-1.2	G1334N	Neutral	0.022
BRCA1	P38398-1.2	G1334P	Neutral	0.039
BRCA1	P38398-1.2	G1334Q	Neutral	0.065
BRCA1	P38398-1.2	G1334R	Neutral	0.128
BRCA1	P38398-1.2	G1334S	Neutral	0.013
BRCA1	P38398-1.2	G1334T	Neutral	0.042
BRCA1	P38398-1.2	G1334V	Neutral	0.075
BRCA1	P38398-1.2	G1334W	Neutral	0.167
BRCA1	P38398-1.2	G1334Y	Neutral	0.153
BRCA1	P38398-1.2	L1335A	Neutral	0.192
BRCA1	P38398-1.2	L1335C	Neutral	0.136
BRCA1	P38398-1.2	L1335D	Neutral	0.289
BRCA1	P38398-1.2	L1335E	Neutral	0.16
BRCA1	P38398-1.2	L1335F	Neutral	0.057
BRCA1	P38398-1.2	L1335G	Pathogenic	0.518
BRCA1	P38398-1.2	L1335H	Neutral	0.136
BRCA1	P38398-1.2	L1335I	Neutral	0.023
BRCA1	P38398-1.2	L1335K	Neutral	0.107
BRCA1	P38398-1.2	L1335M	Neutral	0.022
BRCA1	P38398-1.2	L1335N	Neutral	0.202
BRCA1	P38398-1.2	L1335P	Neutral	0.229
BRCA1	P38398-1.2	L1335Q	Neutral	0.106
BRCA1	P38398-1.2	L1335R	Neutral	0.138
BRCA1	P38398-1.2	L1335S	Neutral	0.229
BRCA1	P38398-1.2	L1335T	Neutral	0.118
BRCA1	P38398-1.2	L1335V	Neutral	0.048
BRCA1	P38398-1.2	L1335W	Neutral	0.189
BRCA1	P38398-1.2	L1335Y	Neutral	0.09
BRCA1	P38398-1.2	S1336A	Neutral	0.075
BRCA1	P38398-1.2	S1336C	Neutral	0.162
BRCA1	P38398-1.2	S1336D	Neutral	0.131
BRCA1	P38398-1.2	S1336E	Neutral	0.184
BRCA1	P38398-1.2	S1336F	Neutral	0.448
BRCA1	P38398-1.2	S1336G	Neutral	0.151
BRCA1	P38398-1.2	S1336H	Neutral	0.285
BRCA1	P38398-1.2	S1336I	Neutral	0.388
BRCA1	P38398-1.2	S1336K	Neutral	0.285
BRCA1	P38398-1.2	S1336L	Neutral	0.389
BRCA1	P38398-1.2	S1336M	Neutral	0.308
BRCA1	P38398-1.2	S1336N	Neutral	0.105
BRCA1	P38398-1.2	S1336P	Neutral	0.175
BRCA1	P38398-1.2	S1336Q	Neutral	0.202
BRCA1	P38398-1.2	S1336R	Neutral	0.433
BRCA1	P38398-1.2	S1336T	Neutral	0.099
BRCA1	P38398-1.2	S1336V	Neutral	0.296
BRCA1	P38398-1.2	S1336W	Pathogenic	0.683
BRCA1	P38398-1.2	S1336Y	Neutral	0.485
BRCA1	P38398-1.2	D1337A	Neutral	0.186
BRCA1	P38398-1.2	D1337C	Neutral	0.175
BRCA1	P38398-1.2	D1337E	Neutral	0.045
BRCA1	P38398-1.2	D1337F	Neutral	0.332
BRCA1	P38398-1.2	D1337G	Neutral	0.195
BRCA1	P38398-1.2	D1337H	Neutral	0.145
BRCA1	P38398-1.2	D1337I	Neutral	0.28
BRCA1	P38398-1.2	D1337K	Neutral	0.201
BRCA1	P38398-1.2	D1337L	Neutral	0.36
BRCA1	P38398-1.2	D1337M	Neutral	0.282
BRCA1	P38398-1.2	D1337N	Neutral	0.049
BRCA1	P38398-1.2	D1337P	Neutral	0.086
BRCA1	P38398-1.2	D1337Q	Neutral	0.098
BRCA1	P38398-1.2	D1337R	Neutral	0.325
BRCA1	P38398-1.2	D1337S	Neutral	0.088
BRCA1	P38398-1.2	D1337T	Neutral	0.089
BRCA1	P38398-1.2	D1337V	Neutral	0.205
BRCA1	P38398-1.2	D1337W	Pathogenic	0.569
BRCA1	P38398-1.2	D1337Y	Neutral	0.366
BRCA1	P38398-1.2	K1338A	Neutral	0.149
BRCA1	P38398-1.2	K1338C	Neutral	0.191
BRCA1	P38398-1.2	K1338D	Neutral	0.095
BRCA1	P38398-1.2	K1338E	Neutral	0.033
BRCA1	P38398-1.2	K1338F	Neutral	0.072
BRCA1	P38398-1.2	K1338G	Neutral	0.28
BRCA1	P38398-1.2	K1338H	Neutral	0.054
BRCA1	P38398-1.2	K1338I	Neutral	0.091
BRCA1	P38398-1.2	K1338L	Neutral	0.065
BRCA1	P38398-1.2	K1338M	Neutral	0.046
BRCA1	P38398-1.2	K1338N	Neutral	0.061
BRCA1	P38398-1.2	K1338P	Neutral	0.095
BRCA1	P38398-1.2	K1338Q	Neutral	0.029
BRCA1	P38398-1.2	K1338R	Neutral	0.018
BRCA1	P38398-1.2	K1338S	Neutral	0.097
BRCA1	P38398-1.2	K1338T	Neutral	0.09
BRCA1	P38398-1.2	K1338V	Neutral	0.097
BRCA1	P38398-1.2	K1338W	Neutral	0.126
BRCA1	P38398-1.2	K1338Y	Neutral	0.059
BRCA1	P38398-1.2	E1339A	Neutral	0.204
BRCA1	P38398-1.2	E1339C	Neutral	0.331
BRCA1	P38398-1.2	E1339D	Neutral	0.049
BRCA1	P38398-1.2	E1339F	Neutral	0.266
BRCA1	P38398-1.2	E1339G	Neutral	0.362
BRCA1	P38398-1.2	E1339H	Neutral	0.079
BRCA1	P38398-1.2	E1339I	Neutral	0.221
BRCA1	P38398-1.2	E1339K	Neutral	0.081
BRCA1	P38398-1.2	E1339L	Neutral	0.221
BRCA1	P38398-1.2	E1339M	Neutral	0.166
BRCA1	P38398-1.2	E1339N	Neutral	0.087
BRCA1	P38398-1.2	E1339P	Neutral	0.132
BRCA1	P38398-1.2	E1339Q	Neutral	0.037
BRCA1	P38398-1.2	E1339R	Neutral	0.144
BRCA1	P38398-1.2	E1339S	Neutral	0.136
BRCA1	P38398-1.2	E1339T	Neutral	0.126
BRCA1	P38398-1.2	E1339V	Neutral	0.135
BRCA1	P38398-1.2	E1339W	Neutral	0.401
BRCA1	P38398-1.2	E1339Y	Neutral	0.226
BRCA1	P38398-1.2	L1340A	Neutral	0.038
BRCA1	P38398-1.2	L1340C	Neutral	0.026
BRCA1	P38398-1.2	L1340D	Neutral	0.063
BRCA1	P38398-1.2	L1340E	Neutral	0.031
BRCA1	P38398-1.2	L1340F	Neutral	0.01
BRCA1	P38398-1.2	L1340G	Neutral	0.151
BRCA1	P38398-1.2	L1340H	Neutral	0.026
BRCA1	P38398-1.2	L1340I	Neutral	0.004
BRCA1	P38398-1.2	L1340K	Neutral	0.02
BRCA1	P38398-1.2	L1340M	Neutral	0.004
BRCA1	P38398-1.2	L1340N	Neutral	0.04
BRCA1	P38398-1.2	L1340P	Neutral	0.047
BRCA1	P38398-1.2	L1340Q	Neutral	0.019
BRCA1	P38398-1.2	L1340R	Neutral	0.026
BRCA1	P38398-1.2	L1340S	Neutral	0.047
BRCA1	P38398-1.2	L1340T	Neutral	0.022
BRCA1	P38398-1.2	L1340V	Neutral	0.008
BRCA1	P38398-1.2	L1340W	Neutral	0.037
BRCA1	P38398-1.2	L1340Y	Neutral	0.016
BRCA1	P38398-1.2	V1341A	Neutral	0.041
BRCA1	P38398-1.2	V1341C	Neutral	0.039
BRCA1	P38398-1.2	V1341D	Neutral	0.068
BRCA1	P38398-1.2	V1341E	Neutral	0.039
BRCA1	P38398-1.2	V1341F	Neutral	0.049
BRCA1	P38398-1.2	V1341G	Neutral	0.16
BRCA1	P38398-1.2	V1341H	Neutral	0.067
BRCA1	P38398-1.2	V1341I	Neutral	0.009
BRCA1	P38398-1.2	V1341K	Neutral	0.067
BRCA1	P38398-1.2	V1341L	Neutral	0.019
BRCA1	P38398-1.2	V1341M	Neutral	0.019
BRCA1	P38398-1.2	V1341N	Neutral	0.061
BRCA1	P38398-1.2	V1341P	Neutral	0.05
BRCA1	P38398-1.2	V1341Q	Neutral	0.044
BRCA1	P38398-1.2	V1341R	Neutral	0.121
BRCA1	P38398-1.2	V1341S	Neutral	0.071
BRCA1	P38398-1.2	V1341T	Neutral	0.023
BRCA1	P38398-1.2	V1341W	Neutral	0.164
BRCA1	P38398-1.2	V1341Y	Neutral	0.056
BRCA1	P38398-1.2	S1342A	Neutral	0.034
BRCA1	P38398-1.2	S1342C	Neutral	0.078
BRCA1	P38398-1.2	S1342D	Neutral	0.062
BRCA1	P38398-1.2	S1342E	Neutral	0.09
BRCA1	P38398-1.2	S1342F	Neutral	0.263
BRCA1	P38398-1.2	S1342G	Neutral	0.073
BRCA1	P38398-1.2	S1342H	Neutral	0.149
BRCA1	P38398-1.2	S1342I	Neutral	0.218
BRCA1	P38398-1.2	S1342K	Neutral	0.149
BRCA1	P38398-1.2	S1342L	Neutral	0.219
BRCA1	P38398-1.2	S1342M	Neutral	0.164
BRCA1	P38398-1.2	S1342N	Neutral	0.049
BRCA1	P38398-1.2	S1342P	Neutral	0.085
BRCA1	P38398-1.2	S1342Q	Neutral	0.1
BRCA1	P38398-1.2	S1342R	Neutral	0.252
BRCA1	P38398-1.2	S1342T	Neutral	0.046
BRCA1	P38398-1.2	S1342V	Neutral	0.156
BRCA1	P38398-1.2	S1342W	Neutral	0.487
BRCA1	P38398-1.2	S1342Y	Neutral	0.293
BRCA1	P38398-1.2	D1343A	Neutral	0.258
BRCA1	P38398-1.2	D1343C	Neutral	0.244
BRCA1	P38398-1.2	D1343E	Neutral	0.067
BRCA1	P38398-1.2	D1343F	Neutral	0.431
BRCA1	P38398-1.2	D1343G	Neutral	0.27
BRCA1	P38398-1.2	D1343H	Neutral	0.206
BRCA1	P38398-1.2	D1343I	Neutral	0.372
BRCA1	P38398-1.2	D1343K	Neutral	0.277
BRCA1	P38398-1.2	D1343L	Neutral	0.461
BRCA1	P38398-1.2	D1343M	Neutral	0.375
BRCA1	P38398-1.2	D1343N	Neutral	0.072
BRCA1	P38398-1.2	D1343P	Neutral	0.126
BRCA1	P38398-1.2	D1343Q	Neutral	0.142
BRCA1	P38398-1.2	D1343R	Neutral	0.424
BRCA1	P38398-1.2	D1343S	Neutral	0.129
BRCA1	P38398-1.2	D1343T	Neutral	0.129
BRCA1	P38398-1.2	D1343V	Neutral	0.282
BRCA1	P38398-1.2	D1343W	Pathogenic	0.668
BRCA1	P38398-1.2	D1343Y	Neutral	0.468
BRCA1	P38398-1.2	D1344A	Neutral	0.283
BRCA1	P38398-1.2	D1344C	Neutral	0.269
BRCA1	P38398-1.2	D1344E	Neutral	0.076
BRCA1	P38398-1.2	D1344F	Neutral	0.463
BRCA1	P38398-1.2	D1344G	Neutral	0.296
BRCA1	P38398-1.2	D1344H	Neutral	0.228
BRCA1	P38398-1.2	D1344I	Neutral	0.403
BRCA1	P38398-1.2	D1344K	Neutral	0.303
BRCA1	P38398-1.2	D1344L	Neutral	0.493
BRCA1	P38398-1.2	D1344M	Neutral	0.406
BRCA1	P38398-1.2	D1344N	Neutral	0.081
BRCA1	P38398-1.2	D1344P	Neutral	0.141
BRCA1	P38398-1.2	D1344Q	Neutral	0.159
BRCA1	P38398-1.2	D1344R	Neutral	0.455
BRCA1	P38398-1.2	D1344S	Neutral	0.144
BRCA1	P38398-1.2	D1344T	Neutral	0.144
BRCA1	P38398-1.2	D1344V	Neutral	0.309
BRCA1	P38398-1.2	D1344W	Pathogenic	0.696
BRCA1	P38398-1.2	D1344Y	Pathogenic	0.5
BRCA1	P38398-1.2	E1345A	Neutral	0.097
BRCA1	P38398-1.2	E1345C	Neutral	0.172
BRCA1	P38398-1.2	E1345D	Neutral	0.021
BRCA1	P38398-1.2	E1345F	Neutral	0.132
BRCA1	P38398-1.2	E1345G	Neutral	0.192
BRCA1	P38398-1.2	E1345H	Neutral	0.035
BRCA1	P38398-1.2	E1345I	Neutral	0.106
BRCA1	P38398-1.2	E1345K	Neutral	0.036
BRCA1	P38398-1.2	E1345L	Neutral	0.107
BRCA1	P38398-1.2	E1345M	Neutral	0.077
BRCA1	P38398-1.2	E1345N	Neutral	0.038
BRCA1	P38398-1.2	E1345P	Neutral	0.06
BRCA1	P38398-1.2	E1345Q	Neutral	0.016
BRCA1	P38398-1.2	E1345R	Neutral	0.066
BRCA1	P38398-1.2	E1345S	Neutral	0.062
BRCA1	P38398-1.2	E1345T	Neutral	0.057
BRCA1	P38398-1.2	E1345V	Neutral	0.062
BRCA1	P38398-1.2	E1345W	Neutral	0.219
BRCA1	P38398-1.2	E1345Y	Neutral	0.109
BRCA1	P38398-1.2	E1346A	Neutral	0.228
BRCA1	P38398-1.2	E1346C	Neutral	0.363
BRCA1	P38398-1.2	E1346D	Neutral	0.056
BRCA1	P38398-1.2	E1346F	Neutral	0.294
BRCA1	P38398-1.2	E1346G	Neutral	0.395
BRCA1	P38398-1.2	E1346H	Neutral	0.09
BRCA1	P38398-1.2	E1346I	Neutral	0.246
BRCA1	P38398-1.2	E1346K	Neutral	0.092
BRCA1	P38398-1.2	E1346L	Neutral	0.247
BRCA1	P38398-1.2	E1346M	Neutral	0.187
BRCA1	P38398-1.2	E1346N	Neutral	0.099
BRCA1	P38398-1.2	E1346P	Neutral	0.15
BRCA1	P38398-1.2	E1346Q	Neutral	0.042
BRCA1	P38398-1.2	E1346R	Neutral	0.163
BRCA1	P38398-1.2	E1346S	Neutral	0.153
BRCA1	P38398-1.2	E1346T	Neutral	0.142
BRCA1	P38398-1.2	E1346V	Neutral	0.152
BRCA1	P38398-1.2	E1346W	Neutral	0.435
BRCA1	P38398-1.2	E1346Y	Neutral	0.252
BRCA1	P38398-1.2	R1347A	Neutral	0.43
BRCA1	P38398-1.2	R1347C	Pathogenic	0.503
BRCA1	P38398-1.2	R1347D	Neutral	0.394
BRCA1	P38398-1.2	R1347E	Neutral	0.174
BRCA1	P38398-1.2	R1347F	Neutral	0.251
BRCA1	P38398-1.2	R1347G	Pathogenic	0.625
BRCA1	P38398-1.2	R1347H	Neutral	0.145
BRCA1	P38398-1.2	R1347I	Neutral	0.3
BRCA1	P38398-1.2	R1347K	Neutral	0.054
BRCA1	P38398-1.2	R1347L	Neutral	0.23
BRCA1	P38398-1.2	R1347M	Neutral	0.173
BRCA1	P38398-1.2	R1347N	Neutral	0.219
BRCA1	P38398-1.2	R1347P	Neutral	0.393
BRCA1	P38398-1.2	R1347Q	Neutral	0.115
BRCA1	P38398-1.2	R1347S	Neutral	0.399
BRCA1	P38398-1.2	R1347T	Neutral	0.298
BRCA1	P38398-1.2	R1347V	Neutral	0.398
BRCA1	P38398-1.2	R1347W	Neutral	0.258
BRCA1	P38398-1.2	R1347Y	Neutral	0.172
BRCA1	P38398-1.2	G1348A	Neutral	0.037
BRCA1	P38398-1.2	G1348C	Neutral	0.147
BRCA1	P38398-1.2	G1348D	Neutral	0.085
BRCA1	P38398-1.2	G1348E	Neutral	0.167
BRCA1	P38398-1.2	G1348F	Neutral	0.335
BRCA1	P38398-1.2	G1348H	Neutral	0.199
BRCA1	P38398-1.2	G1348I	Neutral	0.362
BRCA1	P38398-1.2	G1348K	Neutral	0.263
BRCA1	P38398-1.2	G1348L	Neutral	0.363
BRCA1	P38398-1.2	G1348M	Neutral	0.285
BRCA1	P38398-1.2	G1348N	Neutral	0.068
BRCA1	P38398-1.2	G1348P	Neutral	0.116
BRCA1	P38398-1.2	G1348Q	Neutral	0.185
BRCA1	P38398-1.2	G1348R	Neutral	0.322
BRCA1	P38398-1.2	G1348S	Neutral	0.042
BRCA1	P38398-1.2	G1348T	Neutral	0.124
BRCA1	P38398-1.2	G1348V	Neutral	0.208
BRCA1	P38398-1.2	G1348W	Neutral	0.393
BRCA1	P38398-1.2	G1348Y	Neutral	0.369
BRCA1	P38398-1.2	T1349A	Neutral	0.015
BRCA1	P38398-1.2	T1349C	Neutral	0.014
BRCA1	P38398-1.2	T1349D	Neutral	0.013
BRCA1	P38398-1.2	T1349E	Neutral	0.017
BRCA1	P38398-1.2	T1349F	Neutral	0.042
BRCA1	P38398-1.2	T1349G	Neutral	0.046
BRCA1	P38398-1.2	T1349H	Neutral	0.03
BRCA1	P38398-1.2	T1349I	Neutral	0.024
BRCA1	P38398-1.2	T1349K	Neutral	0.03
BRCA1	P38398-1.2	T1349L	Neutral	0.024
BRCA1	P38398-1.2	T1349M	Neutral	0.024
BRCA1	P38398-1.2	T1349N	Neutral	0.009
BRCA1	P38398-1.2	T1349P	Neutral	0.013
BRCA1	P38398-1.2	T1349Q	Neutral	0.019
BRCA1	P38398-1.2	T1349R	Neutral	0.04
BRCA1	P38398-1.2	T1349S	Neutral	0.009
BRCA1	P38398-1.2	T1349V	Neutral	0.011
BRCA1	P38398-1.2	T1349W	Neutral	0.076
BRCA1	P38398-1.2	T1349Y	Neutral	0.049
BRCA1	P38398-1.2	G1350A	Neutral	0.027
BRCA1	P38398-1.2	G1350C	Neutral	0.112
BRCA1	P38398-1.2	G1350D	Neutral	0.064
BRCA1	P38398-1.2	G1350E	Neutral	0.129
BRCA1	P38398-1.2	G1350F	Neutral	0.27
BRCA1	P38398-1.2	G1350H	Neutral	0.154
BRCA1	P38398-1.2	G1350I	Neutral	0.294
BRCA1	P38398-1.2	G1350K	Neutral	0.207
BRCA1	P38398-1.2	G1350L	Neutral	0.295
BRCA1	P38398-1.2	G1350M	Neutral	0.227
BRCA1	P38398-1.2	G1350N	Neutral	0.051
BRCA1	P38398-1.2	G1350P	Neutral	0.088
BRCA1	P38398-1.2	G1350Q	Neutral	0.143
BRCA1	P38398-1.2	G1350R	Neutral	0.259
BRCA1	P38398-1.2	G1350S	Neutral	0.031
BRCA1	P38398-1.2	G1350T	Neutral	0.094
BRCA1	P38398-1.2	G1350V	Neutral	0.161
BRCA1	P38398-1.2	G1350W	Neutral	0.322
BRCA1	P38398-1.2	G1350Y	Neutral	0.301
BRCA1	P38398-1.2	L1351A	Pathogenic	0.565
BRCA1	P38398-1.2	L1351C	Neutral	0.463
BRCA1	P38398-1.2	L1351D	Pathogenic	0.69
BRCA1	P38398-1.2	L1351E	Pathogenic	0.509
BRCA1	P38398-1.2	L1351F	Neutral	0.25
BRCA1	P38398-1.2	L1351G	Pathogenic	0.854
BRCA1	P38398-1.2	L1351H	Neutral	0.463
BRCA1	P38398-1.2	L1351I	Neutral	0.112
BRCA1	P38398-1.2	L1351K	Neutral	0.396
BRCA1	P38398-1.2	L1351M	Neutral	0.111
BRCA1	P38398-1.2	L1351N	Pathogenic	0.581
BRCA1	P38398-1.2	L1351P	Pathogenic	0.619
BRCA1	P38398-1.2	L1351Q	Neutral	0.394
BRCA1	P38398-1.2	L1351R	Neutral	0.467
BRCA1	P38398-1.2	L1351S	Pathogenic	0.619
BRCA1	P38398-1.2	L1351T	Neutral	0.421
BRCA1	P38398-1.2	L1351V	Neutral	0.215
BRCA1	P38398-1.2	L1351W	Pathogenic	0.56
BRCA1	P38398-1.2	L1351Y	Neutral	0.351
BRCA1	P38398-1.2	E1352A	Neutral	0.296
BRCA1	P38398-1.2	E1352C	Neutral	0.447
BRCA1	P38398-1.2	E1352D	Neutral	0.077
BRCA1	P38398-1.2	E1352F	Neutral	0.372
BRCA1	P38398-1.2	E1352G	Neutral	0.481
BRCA1	P38398-1.2	E1352H	Neutral	0.123
BRCA1	P38398-1.2	E1352I	Neutral	0.317
BRCA1	P38398-1.2	E1352K	Neutral	0.126
BRCA1	P38398-1.2	E1352L	Neutral	0.317
BRCA1	P38398-1.2	E1352M	Neutral	0.246
BRCA1	P38398-1.2	E1352N	Neutral	0.135
BRCA1	P38398-1.2	E1352P	Neutral	0.2
BRCA1	P38398-1.2	E1352Q	Neutral	0.059
BRCA1	P38398-1.2	E1352R	Neutral	0.216
BRCA1	P38398-1.2	E1352S	Neutral	0.204
BRCA1	P38398-1.2	E1352T	Neutral	0.191
BRCA1	P38398-1.2	E1352V	Neutral	0.203
BRCA1	P38398-1.2	E1352W	Pathogenic	0.522
BRCA1	P38398-1.2	E1352Y	Neutral	0.323
BRCA1	P38398-1.2	E1353A	Neutral	0.25
BRCA1	P38398-1.2	E1353C	Neutral	0.392
BRCA1	P38398-1.2	E1353D	Neutral	0.063
BRCA1	P38398-1.2	E1353F	Neutral	0.32
BRCA1	P38398-1.2	E1353G	Neutral	0.424
BRCA1	P38398-1.2	E1353H	Neutral	0.101
BRCA1	P38398-1.2	E1353I	Neutral	0.269
BRCA1	P38398-1.2	E1353K	Neutral	0.103
BRCA1	P38398-1.2	E1353L	Neutral	0.27
BRCA1	P38398-1.2	E1353M	Neutral	0.206
BRCA1	P38398-1.2	E1353N	Neutral	0.11
BRCA1	P38398-1.2	E1353P	Neutral	0.166
BRCA1	P38398-1.2	E1353Q	Neutral	0.047
BRCA1	P38398-1.2	E1353R	Neutral	0.18
BRCA1	P38398-1.2	E1353S	Neutral	0.17
BRCA1	P38398-1.2	E1353T	Neutral	0.158
BRCA1	P38398-1.2	E1353V	Neutral	0.169
BRCA1	P38398-1.2	E1353W	Neutral	0.465
BRCA1	P38398-1.2	E1353Y	Neutral	0.275
BRCA1	P38398-1.2	N1354A	Neutral	0.026
BRCA1	P38398-1.2	N1354C	Neutral	0.025
BRCA1	P38398-1.2	N1354D	Neutral	0.005
BRCA1	P38398-1.2	N1354E	Neutral	0.009
BRCA1	P38398-1.2	N1354F	Neutral	0.045
BRCA1	P38398-1.2	N1354G	Neutral	0.02
BRCA1	P38398-1.2	N1354H	Neutral	0.008
BRCA1	P38398-1.2	N1354I	Neutral	0.036
BRCA1	P38398-1.2	N1354K	Neutral	0.016
BRCA1	P38398-1.2	N1354L	Neutral	0.036
BRCA1	P38398-1.2	N1354M	Neutral	0.025
BRCA1	P38398-1.2	N1354P	Neutral	0.016
BRCA1	P38398-1.2	N1354Q	Neutral	0.01
BRCA1	P38398-1.2	N1354R	Neutral	0.022
BRCA1	P38398-1.2	N1354S	Neutral	0.008
BRCA1	P38398-1.2	N1354T	Neutral	0.007
BRCA1	P38398-1.2	N1354V	Neutral	0.024
BRCA1	P38398-1.2	N1354W	Neutral	0.112
BRCA1	P38398-1.2	N1354Y	Neutral	0.037
BRCA1	P38398-1.2	N1355A	Neutral	0.039
BRCA1	P38398-1.2	N1355C	Neutral	0.037
BRCA1	P38398-1.2	N1355D	Neutral	0.008
BRCA1	P38398-1.2	N1355E	Neutral	0.014
BRCA1	P38398-1.2	N1355F	Neutral	0.067
BRCA1	P38398-1.2	N1355G	Neutral	0.029
BRCA1	P38398-1.2	N1355H	Neutral	0.012
BRCA1	P38398-1.2	N1355I	Neutral	0.053
BRCA1	P38398-1.2	N1355K	Neutral	0.024
BRCA1	P38398-1.2	N1355L	Neutral	0.053
BRCA1	P38398-1.2	N1355M	Neutral	0.038
BRCA1	P38398-1.2	N1355P	Neutral	0.024
BRCA1	P38398-1.2	N1355Q	Neutral	0.015
BRCA1	P38398-1.2	N1355R	Neutral	0.032
BRCA1	P38398-1.2	N1355S	Neutral	0.012
BRCA1	P38398-1.2	N1355T	Neutral	0.011
BRCA1	P38398-1.2	N1355V	Neutral	0.036
BRCA1	P38398-1.2	N1355W	Neutral	0.16
BRCA1	P38398-1.2	N1355Y	Neutral	0.055
BRCA1	P38398-1.2	Q1356A	Neutral	0.039
BRCA1	P38398-1.2	Q1356C	Neutral	0.052
BRCA1	P38398-1.2	Q1356D	Neutral	0.016
BRCA1	P38398-1.2	Q1356E	Neutral	0.005
BRCA1	P38398-1.2	Q1356F	Neutral	0.044
BRCA1	P38398-1.2	Q1356G	Neutral	0.083
BRCA1	P38398-1.2	Q1356H	Neutral	0.011
BRCA1	P38398-1.2	Q1356I	Neutral	0.035
BRCA1	P38398-1.2	Q1356K	Neutral	0.011
BRCA1	P38398-1.2	Q1356L	Neutral	0.025
BRCA1	P38398-1.2	Q1356M	Neutral	0.012
BRCA1	P38398-1.2	Q1356N	Neutral	0.015
BRCA1	P38398-1.2	Q1356P	Neutral	0.024
BRCA1	P38398-1.2	Q1356R	Neutral	0.014
BRCA1	P38398-1.2	Q1356S	Neutral	0.024
BRCA1	P38398-1.2	Q1356T	Neutral	0.022
BRCA1	P38398-1.2	Q1356V	Neutral	0.024
BRCA1	P38398-1.2	Q1356W	Neutral	0.056
BRCA1	P38398-1.2	Q1356Y	Neutral	0.025
BRCA1	P38398-1.2	E1357A	Neutral	0.067
BRCA1	P38398-1.2	E1357C	Neutral	0.122
BRCA1	P38398-1.2	E1357D	Neutral	0.014
BRCA1	P38398-1.2	E1357F	Neutral	0.093
BRCA1	P38398-1.2	E1357G	Neutral	0.138
BRCA1	P38398-1.2	E1357H	Neutral	0.024
BRCA1	P38398-1.2	E1357I	Neutral	0.074
BRCA1	P38398-1.2	E1357K	Neutral	0.024
BRCA1	P38398-1.2	E1357L	Neutral	0.074
BRCA1	P38398-1.2	E1357M	Neutral	0.053
BRCA1	P38398-1.2	E1357N	Neutral	0.026
BRCA1	P38398-1.2	E1357P	Neutral	0.041
BRCA1	P38398-1.2	E1357Q	Neutral	0.011
BRCA1	P38398-1.2	E1357R	Neutral	0.045
BRCA1	P38398-1.2	E1357S	Neutral	0.042
BRCA1	P38398-1.2	E1357T	Neutral	0.039
BRCA1	P38398-1.2	E1357V	Neutral	0.042
BRCA1	P38398-1.2	E1357W	Neutral	0.159
BRCA1	P38398-1.2	E1357Y	Neutral	0.076
BRCA1	P38398-1.2	E1358A	Neutral	0.154
BRCA1	P38398-1.2	E1358C	Neutral	0.26
BRCA1	P38398-1.2	E1358D	Neutral	0.035
BRCA1	P38398-1.2	E1358F	Neutral	0.204
BRCA1	P38398-1.2	E1358G	Neutral	0.286
BRCA1	P38398-1.2	E1358H	Neutral	0.057
BRCA1	P38398-1.2	E1358I	Neutral	0.167
BRCA1	P38398-1.2	E1358K	Neutral	0.059
BRCA1	P38398-1.2	E1358L	Neutral	0.167
BRCA1	P38398-1.2	E1358M	Neutral	0.124
BRCA1	P38398-1.2	E1358N	Neutral	0.063
BRCA1	P38398-1.2	E1358P	Neutral	0.098
BRCA1	P38398-1.2	E1358Q	Neutral	0.026
BRCA1	P38398-1.2	E1358R	Neutral	0.107
BRCA1	P38398-1.2	E1358S	Neutral	0.1
BRCA1	P38398-1.2	E1358T	Neutral	0.093
BRCA1	P38398-1.2	E1358V	Neutral	0.099
BRCA1	P38398-1.2	E1358W	Neutral	0.321
BRCA1	P38398-1.2	E1358Y	Neutral	0.171
BRCA1	P38398-1.2	Q1359A	Neutral	0.228
BRCA1	P38398-1.2	Q1359C	Neutral	0.284
BRCA1	P38398-1.2	Q1359D	Neutral	0.107
BRCA1	P38398-1.2	Q1359E	Neutral	0.038
BRCA1	P38398-1.2	Q1359F	Neutral	0.25
BRCA1	P38398-1.2	Q1359G	Neutral	0.395
BRCA1	P38398-1.2	Q1359H	Neutral	0.073
BRCA1	P38398-1.2	Q1359I	Neutral	0.207
BRCA1	P38398-1.2	Q1359K	Neutral	0.074
BRCA1	P38398-1.2	Q1359L	Neutral	0.154
BRCA1	P38398-1.2	Q1359M	Neutral	0.081
BRCA1	P38398-1.2	Q1359N	Neutral	0.098
BRCA1	P38398-1.2	Q1359P	Neutral	0.149
BRCA1	P38398-1.2	Q1359R	Neutral	0.096
BRCA1	P38398-1.2	Q1359S	Neutral	0.153
BRCA1	P38398-1.2	Q1359T	Neutral	0.142
BRCA1	P38398-1.2	Q1359V	Neutral	0.152
BRCA1	P38398-1.2	Q1359W	Neutral	0.3
BRCA1	P38398-1.2	Q1359Y	Neutral	0.158
BRCA1	P38398-1.2	S1360A	Neutral	0.029
BRCA1	P38398-1.2	S1360C	Neutral	0.067
BRCA1	P38398-1.2	S1360D	Neutral	0.053
BRCA1	P38398-1.2	S1360E	Neutral	0.078
BRCA1	P38398-1.2	S1360F	Neutral	0.233
BRCA1	P38398-1.2	S1360G	Neutral	0.063
BRCA1	P38398-1.2	S1360H	Neutral	0.13
BRCA1	P38398-1.2	S1360I	Neutral	0.192
BRCA1	P38398-1.2	S1360K	Neutral	0.13
BRCA1	P38398-1.2	S1360L	Neutral	0.193
BRCA1	P38398-1.2	S1360M	Neutral	0.143
BRCA1	P38398-1.2	S1360N	Neutral	0.042
BRCA1	P38398-1.2	S1360P	Neutral	0.074
BRCA1	P38398-1.2	S1360Q	Neutral	0.087
BRCA1	P38398-1.2	S1360R	Neutral	0.223
BRCA1	P38398-1.2	S1360T	Neutral	0.04
BRCA1	P38398-1.2	S1360V	Neutral	0.136
BRCA1	P38398-1.2	S1360W	Neutral	0.447
BRCA1	P38398-1.2	S1360Y	Neutral	0.261
BRCA1	P38398-1.2	M1361A	Neutral	0.026
BRCA1	P38398-1.2	M1361C	Neutral	0.018
BRCA1	P38398-1.2	M1361D	Neutral	0.031
BRCA1	P38398-1.2	M1361E	Neutral	0.015
BRCA1	P38398-1.2	M1361F	Neutral	0.007
BRCA1	P38398-1.2	M1361G	Neutral	0.078
BRCA1	P38398-1.2	M1361H	Neutral	0.012
BRCA1	P38398-1.2	M1361I	Neutral	0.004
BRCA1	P38398-1.2	M1361K	Neutral	0.009
BRCA1	P38398-1.2	M1361L	Neutral	0.003
BRCA1	P38398-1.2	M1361N	Neutral	0.02
BRCA1	P38398-1.2	M1361P	Neutral	0.023
BRCA1	P38398-1.2	M1361Q	Neutral	0.007
BRCA1	P38398-1.2	M1361R	Neutral	0.013
BRCA1	P38398-1.2	M1361S	Neutral	0.023
BRCA1	P38398-1.2	M1361T	Neutral	0.015
BRCA1	P38398-1.2	M1361V	Neutral	0.006
BRCA1	P38398-1.2	M1361W	Neutral	0.018
BRCA1	P38398-1.2	M1361Y	Neutral	0.011
BRCA1	P38398-1.2	D1362A	Neutral	0.271
BRCA1	P38398-1.2	D1362C	Neutral	0.258
BRCA1	P38398-1.2	D1362E	Neutral	0.072
BRCA1	P38398-1.2	D1362F	Neutral	0.448
BRCA1	P38398-1.2	D1362G	Neutral	0.284
BRCA1	P38398-1.2	D1362H	Neutral	0.217
BRCA1	P38398-1.2	D1362I	Neutral	0.389
BRCA1	P38398-1.2	D1362K	Neutral	0.291
BRCA1	P38398-1.2	D1362L	Neutral	0.478
BRCA1	P38398-1.2	D1362M	Neutral	0.391
BRCA1	P38398-1.2	D1362N	Neutral	0.077
BRCA1	P38398-1.2	D1362P	Neutral	0.133
BRCA1	P38398-1.2	D1362Q	Neutral	0.151
BRCA1	P38398-1.2	D1362R	Neutral	0.441
BRCA1	P38398-1.2	D1362S	Neutral	0.137
BRCA1	P38398-1.2	D1362T	Neutral	0.137
BRCA1	P38398-1.2	D1362V	Neutral	0.297
BRCA1	P38398-1.2	D1362W	Pathogenic	0.683
BRCA1	P38398-1.2	D1362Y	Neutral	0.485
BRCA1	P38398-1.2	S1363A	Neutral	0.069
BRCA1	P38398-1.2	S1363C	Neutral	0.15
BRCA1	P38398-1.2	S1363D	Neutral	0.121
BRCA1	P38398-1.2	S1363E	Neutral	0.171
BRCA1	P38398-1.2	S1363F	Neutral	0.427
BRCA1	P38398-1.2	S1363G	Neutral	0.141
BRCA1	P38398-1.2	S1363H	Neutral	0.268
BRCA1	P38398-1.2	S1363I	Neutral	0.368
BRCA1	P38398-1.2	S1363K	Neutral	0.268
BRCA1	P38398-1.2	S1363L	Neutral	0.369
BRCA1	P38398-1.2	S1363M	Neutral	0.29
BRCA1	P38398-1.2	S1363N	Neutral	0.097
BRCA1	P38398-1.2	S1363P	Neutral	0.163
BRCA1	P38398-1.2	S1363Q	Neutral	0.189
BRCA1	P38398-1.2	S1363R	Neutral	0.412
BRCA1	P38398-1.2	S1363T	Neutral	0.092
BRCA1	P38398-1.2	S1363V	Neutral	0.279
BRCA1	P38398-1.2	S1363W	Pathogenic	0.664
BRCA1	P38398-1.2	S1363Y	Neutral	0.463
BRCA1	P38398-1.2	N1364A	Neutral	0.022
BRCA1	P38398-1.2	N1364C	Neutral	0.02
BRCA1	P38398-1.2	N1364D	Neutral	0.004
BRCA1	P38398-1.2	N1364E	Neutral	0.008
BRCA1	P38398-1.2	N1364F	Neutral	0.037
BRCA1	P38398-1.2	N1364G	Neutral	0.016
BRCA1	P38398-1.2	N1364H	Neutral	0.006
BRCA1	P38398-1.2	N1364I	Neutral	0.029
BRCA1	P38398-1.2	N1364K	Neutral	0.013
BRCA1	P38398-1.2	N1364L	Neutral	0.029
BRCA1	P38398-1.2	N1364M	Neutral	0.021
BRCA1	P38398-1.2	N1364P	Neutral	0.013
BRCA1	P38398-1.2	N1364Q	Neutral	0.008
BRCA1	P38398-1.2	N1364R	Neutral	0.018
BRCA1	P38398-1.2	N1364S	Neutral	0.007
BRCA1	P38398-1.2	N1364T	Neutral	0.006
BRCA1	P38398-1.2	N1364V	Neutral	0.02
BRCA1	P38398-1.2	N1364W	Neutral	0.093
BRCA1	P38398-1.2	N1364Y	Neutral	0.03
BRCA1	P38398-1.2	L1365A	Pathogenic	0.565
BRCA1	P38398-1.2	L1365C	Neutral	0.463
BRCA1	P38398-1.2	L1365D	Pathogenic	0.69
BRCA1	P38398-1.2	L1365E	Pathogenic	0.509
BRCA1	P38398-1.2	L1365F	Neutral	0.25
BRCA1	P38398-1.2	L1365G	Pathogenic	0.854
BRCA1	P38398-1.2	L1365H	Neutral	0.463
BRCA1	P38398-1.2	L1365I	Neutral	0.112
BRCA1	P38398-1.2	L1365K	Neutral	0.396
BRCA1	P38398-1.2	L1365M	Neutral	0.111
BRCA1	P38398-1.2	L1365N	Pathogenic	0.581
BRCA1	P38398-1.2	L1365P	Pathogenic	0.619
BRCA1	P38398-1.2	L1365Q	Neutral	0.394
BRCA1	P38398-1.2	L1365R	Neutral	0.467
BRCA1	P38398-1.2	L1365S	Pathogenic	0.619
BRCA1	P38398-1.2	L1365T	Neutral	0.421
BRCA1	P38398-1.2	L1365V	Neutral	0.215
BRCA1	P38398-1.2	L1365W	Pathogenic	0.56
BRCA1	P38398-1.2	L1365Y	Neutral	0.351
BRCA1	P38398-1.2	G1366A	Neutral	0.069
BRCA1	P38398-1.2	G1366C	Neutral	0.25
BRCA1	P38398-1.2	G1366D	Neutral	0.153
BRCA1	P38398-1.2	G1366E	Neutral	0.28
BRCA1	P38398-1.2	G1366F	Neutral	0.494
BRCA1	P38398-1.2	G1366H	Neutral	0.324
BRCA1	P38398-1.2	G1366I	Pathogenic	0.524
BRCA1	P38398-1.2	G1366K	Neutral	0.408
BRCA1	P38398-1.2	G1366L	Pathogenic	0.524
BRCA1	P38398-1.2	G1366M	Neutral	0.436
BRCA1	P38398-1.2	G1366N	Neutral	0.123
BRCA1	P38398-1.2	G1366P	Neutral	0.203
BRCA1	P38398-1.2	G1366Q	Neutral	0.305
BRCA1	P38398-1.2	G1366R	Neutral	0.479
BRCA1	P38398-1.2	G1366S	Neutral	0.079
BRCA1	P38398-1.2	G1366T	Neutral	0.215
BRCA1	P38398-1.2	G1366V	Neutral	0.336
BRCA1	P38398-1.2	G1366W	Pathogenic	0.556
BRCA1	P38398-1.2	G1366Y	Pathogenic	0.531
BRCA1	P38398-1.2	E1367A	Neutral	0.366
BRCA1	P38398-1.2	E1367C	Pathogenic	0.527
BRCA1	P38398-1.2	E1367D	Neutral	0.103
BRCA1	P38398-1.2	E1367F	Neutral	0.449
BRCA1	P38398-1.2	E1367G	Pathogenic	0.56
BRCA1	P38398-1.2	E1367H	Neutral	0.162
BRCA1	P38398-1.2	E1367I	Neutral	0.389
BRCA1	P38398-1.2	E1367K	Neutral	0.165
BRCA1	P38398-1.2	E1367L	Neutral	0.39
BRCA1	P38398-1.2	E1367M	Neutral	0.309
BRCA1	P38398-1.2	E1367N	Neutral	0.176
BRCA1	P38398-1.2	E1367P	Neutral	0.256
BRCA1	P38398-1.2	E1367Q	Neutral	0.079
BRCA1	P38398-1.2	E1367R	Neutral	0.275
BRCA1	P38398-1.2	E1367S	Neutral	0.261
BRCA1	P38398-1.2	E1367T	Neutral	0.245
BRCA1	P38398-1.2	E1367V	Neutral	0.26
BRCA1	P38398-1.2	E1367W	Pathogenic	0.6
BRCA1	P38398-1.2	E1367Y	Neutral	0.396
BRCA1	P38398-1.2	A1368C	Neutral	0.041
BRCA1	P38398-1.2	A1368D	Neutral	0.09
BRCA1	P38398-1.2	A1368E	Neutral	0.093
BRCA1	P38398-1.2	A1368F	Neutral	0.206
BRCA1	P38398-1.2	A1368G	Neutral	0.041
BRCA1	P38398-1.2	A1368H	Neutral	0.154
BRCA1	P38398-1.2	A1368I	Neutral	0.124
BRCA1	P38398-1.2	A1368K	Neutral	0.153
BRCA1	P38398-1.2	A1368L	Neutral	0.124
BRCA1	P38398-1.2	A1368M	Neutral	0.125
BRCA1	P38398-1.2	A1368N	Neutral	0.1
BRCA1	P38398-1.2	A1368P	Neutral	0.064
BRCA1	P38398-1.2	A1368Q	Neutral	0.103
BRCA1	P38398-1.2	A1368R	Neutral	0.195
BRCA1	P38398-1.2	A1368S	Neutral	0.022
BRCA1	P38398-1.2	A1368T	Neutral	0.048
BRCA1	P38398-1.2	A1368V	Neutral	0.061
BRCA1	P38398-1.2	A1368W	Neutral	0.408
BRCA1	P38398-1.2	A1368Y	Neutral	0.232
BRCA1	P38398-1.2	A1369C	Neutral	0.374
BRCA1	P38398-1.2	A1369D	Pathogenic	0.578
BRCA1	P38398-1.2	A1369E	Pathogenic	0.587
BRCA1	P38398-1.2	A1369F	Pathogenic	0.783
BRCA1	P38398-1.2	A1369G	Neutral	0.375
BRCA1	P38398-1.2	A1369H	Pathogenic	0.717
BRCA1	P38398-1.2	A1369I	Pathogenic	0.663
BRCA1	P38398-1.2	A1369K	Pathogenic	0.716
BRCA1	P38398-1.2	A1369L	Pathogenic	0.663
BRCA1	P38398-1.2	A1369M	Pathogenic	0.665
BRCA1	P38398-1.2	A1369N	Pathogenic	0.606
BRCA1	P38398-1.2	A1369P	Neutral	0.485
BRCA1	P38398-1.2	A1369Q	Pathogenic	0.616
BRCA1	P38398-1.2	A1369R	Pathogenic	0.771
BRCA1	P38398-1.2	A1369S	Neutral	0.238
BRCA1	P38398-1.2	A1369T	Neutral	0.413
BRCA1	P38398-1.2	A1369V	Neutral	0.475
BRCA1	P38398-1.2	A1369W	Pathogenic	0.906
BRCA1	P38398-1.2	A1369Y	Pathogenic	0.807
BRCA1	P38398-1.2	S1370A	Neutral	0.139
BRCA1	P38398-1.2	S1370C	Neutral	0.279
BRCA1	P38398-1.2	S1370D	Neutral	0.232
BRCA1	P38398-1.2	S1370E	Neutral	0.311
BRCA1	P38398-1.2	S1370F	Pathogenic	0.62
BRCA1	P38398-1.2	S1370G	Neutral	0.264
BRCA1	P38398-1.2	S1370H	Neutral	0.445
BRCA1	P38398-1.2	S1370I	Pathogenic	0.56
BRCA1	P38398-1.2	S1370K	Neutral	0.444
BRCA1	P38398-1.2	S1370L	Pathogenic	0.561
BRCA1	P38398-1.2	S1370M	Neutral	0.473
BRCA1	P38398-1.2	S1370N	Neutral	0.191
BRCA1	P38398-1.2	S1370P	Neutral	0.298
BRCA1	P38398-1.2	S1370Q	Neutral	0.337
BRCA1	P38398-1.2	S1370R	Pathogenic	0.606
BRCA1	P38398-1.2	S1370T	Neutral	0.181
BRCA1	P38398-1.2	S1370V	Neutral	0.458
BRCA1	P38398-1.2	S1370W	Pathogenic	0.812
BRCA1	P38398-1.2	S1370Y	Pathogenic	0.654
BRCA1	P38398-1.2	G1371A	Neutral	0.087
BRCA1	P38398-1.2	G1371C	Neutral	0.299
BRCA1	P38398-1.2	G1371D	Neutral	0.187
BRCA1	P38398-1.2	G1371E	Neutral	0.332
BRCA1	P38398-1.2	G1371F	Pathogenic	0.555
BRCA1	P38398-1.2	G1371H	Neutral	0.38
BRCA1	P38398-1.2	G1371I	Pathogenic	0.584
BRCA1	P38398-1.2	G1371K	Neutral	0.468
BRCA1	P38398-1.2	G1371L	Pathogenic	0.584
BRCA1	P38398-1.2	G1371M	Neutral	0.496
BRCA1	P38398-1.2	G1371N	Neutral	0.152
BRCA1	P38398-1.2	G1371P	Neutral	0.245
BRCA1	P38398-1.2	G1371Q	Neutral	0.359
BRCA1	P38398-1.2	G1371R	Pathogenic	0.54
BRCA1	P38398-1.2	G1371S	Neutral	0.098
BRCA1	P38398-1.2	G1371T	Neutral	0.26
BRCA1	P38398-1.2	G1371V	Neutral	0.393
BRCA1	P38398-1.2	G1371W	Pathogenic	0.615
BRCA1	P38398-1.2	G1371Y	Pathogenic	0.591
BRCA1	P38398-1.2	C1372A	Neutral	0.113
BRCA1	P38398-1.2	C1372D	Neutral	0.214
BRCA1	P38398-1.2	C1372E	Neutral	0.37
BRCA1	P38398-1.2	C1372F	Neutral	0.339
BRCA1	P38398-1.2	C1372G	Neutral	0.365
BRCA1	P38398-1.2	C1372H	Neutral	0.336
BRCA1	P38398-1.2	C1372I	Neutral	0.218
BRCA1	P38398-1.2	C1372K	Neutral	0.419
BRCA1	P38398-1.2	C1372L	Neutral	0.218
BRCA1	P38398-1.2	C1372M	Neutral	0.22
BRCA1	P38398-1.2	C1372N	Neutral	0.234
BRCA1	P38398-1.2	C1372P	Neutral	0.215
BRCA1	P38398-1.2	C1372Q	Neutral	0.315
BRCA1	P38398-1.2	C1372R	Neutral	0.49
BRCA1	P38398-1.2	C1372S	Neutral	0.138
BRCA1	P38398-1.2	C1372T	Neutral	0.123
BRCA1	P38398-1.2	C1372V	Neutral	0.156
BRCA1	P38398-1.2	C1372W	Neutral	0.486
BRCA1	P38398-1.2	C1372Y	Neutral	0.373
BRCA1	P38398-1.2	E1373A	Neutral	0.104
BRCA1	P38398-1.2	E1373C	Neutral	0.182
BRCA1	P38398-1.2	E1373D	Neutral	0.023
BRCA1	P38398-1.2	E1373F	Neutral	0.14
BRCA1	P38398-1.2	E1373G	Neutral	0.203
BRCA1	P38398-1.2	E1373H	Neutral	0.037
BRCA1	P38398-1.2	E1373I	Neutral	0.113
BRCA1	P38398-1.2	E1373K	Neutral	0.038
BRCA1	P38398-1.2	E1373L	Neutral	0.113
BRCA1	P38398-1.2	E1373M	Neutral	0.082
BRCA1	P38398-1.2	E1373N	Neutral	0.041
BRCA1	P38398-1.2	E1373P	Neutral	0.064
BRCA1	P38398-1.2	E1373Q	Neutral	0.017
BRCA1	P38398-1.2	E1373R	Neutral	0.071
BRCA1	P38398-1.2	E1373S	Neutral	0.066
BRCA1	P38398-1.2	E1373T	Neutral	0.061
BRCA1	P38398-1.2	E1373V	Neutral	0.066
BRCA1	P38398-1.2	E1373W	Neutral	0.231
BRCA1	P38398-1.2	E1373Y	Neutral	0.116
BRCA1	P38398-1.2	S1374A	Neutral	0.214
BRCA1	P38398-1.2	S1374C	Neutral	0.394
BRCA1	P38398-1.2	S1374D	Neutral	0.337
BRCA1	P38398-1.2	S1374E	Neutral	0.432
BRCA1	P38398-1.2	S1374F	Pathogenic	0.732
BRCA1	P38398-1.2	S1374G	Neutral	0.375
BRCA1	P38398-1.2	S1374H	Pathogenic	0.574
BRCA1	P38398-1.2	S1374I	Pathogenic	0.682
BRCA1	P38398-1.2	S1374K	Pathogenic	0.573
BRCA1	P38398-1.2	S1374L	Pathogenic	0.682
BRCA1	P38398-1.2	S1374M	Pathogenic	0.601
BRCA1	P38398-1.2	S1374N	Neutral	0.283
BRCA1	P38398-1.2	S1374P	Neutral	0.417
BRCA1	P38398-1.2	S1374Q	Neutral	0.461
BRCA1	P38398-1.2	S1374R	Pathogenic	0.721
BRCA1	P38398-1.2	S1374T	Neutral	0.271
BRCA1	P38398-1.2	S1374V	Pathogenic	0.587
BRCA1	P38398-1.2	S1374W	Pathogenic	0.879
BRCA1	P38398-1.2	S1374Y	Pathogenic	0.761
BRCA1	P38398-1.2	E1375A	Pathogenic	0.793
BRCA1	P38398-1.2	E1375C	Pathogenic	0.881
BRCA1	P38398-1.2	E1375D	Neutral	0.434
BRCA1	P38398-1.2	E1375F	Pathogenic	0.844
BRCA1	P38398-1.2	E1375G	Pathogenic	0.894
BRCA1	P38398-1.2	E1375H	Pathogenic	0.562
BRCA1	P38398-1.2	E1375I	Pathogenic	0.809
BRCA1	P38398-1.2	E1375K	Pathogenic	0.567
BRCA1	P38398-1.2	E1375L	Pathogenic	0.809
BRCA1	P38398-1.2	E1375M	Pathogenic	0.748
BRCA1	P38398-1.2	E1375N	Pathogenic	0.587
BRCA1	P38398-1.2	E1375P	Pathogenic	0.695
BRCA1	P38398-1.2	E1375Q	Neutral	0.363
BRCA1	P38398-1.2	E1375R	Pathogenic	0.716
BRCA1	P38398-1.2	E1375S	Pathogenic	0.701
BRCA1	P38398-1.2	E1375T	Pathogenic	0.683
BRCA1	P38398-1.2	E1375V	Pathogenic	0.7
BRCA1	P38398-1.2	E1375W	Pathogenic	0.909
BRCA1	P38398-1.2	E1375Y	Pathogenic	0.813
BRCA1	P38398-1.2	T1376A	Neutral	0.39
BRCA1	P38398-1.2	T1376C	Neutral	0.373
BRCA1	P38398-1.2	T1376D	Neutral	0.346
BRCA1	P38398-1.2	T1376E	Neutral	0.42
BRCA1	P38398-1.2	T1376F	Pathogenic	0.647
BRCA1	P38398-1.2	T1376G	Pathogenic	0.668
BRCA1	P38398-1.2	T1376H	Pathogenic	0.564
BRCA1	P38398-1.2	T1376I	Neutral	0.5
BRCA1	P38398-1.2	T1376K	Pathogenic	0.562
BRCA1	P38398-1.2	T1376L	Pathogenic	0.5
BRCA1	P38398-1.2	T1376M	Pathogenic	0.502
BRCA1	P38398-1.2	T1376N	Neutral	0.274
BRCA1	P38398-1.2	T1376P	Neutral	0.354
BRCA1	P38398-1.2	T1376Q	Neutral	0.449
BRCA1	P38398-1.2	T1376R	Pathogenic	0.631
BRCA1	P38398-1.2	T1376S	Neutral	0.279
BRCA1	P38398-1.2	T1376V	Neutral	0.315
BRCA1	P38398-1.2	T1376W	Pathogenic	0.772
BRCA1	P38398-1.2	T1376Y	Pathogenic	0.681
BRCA1	P38398-1.2	S1377A	Neutral	0.016
BRCA1	P38398-1.2	S1377C	Neutral	0.038
BRCA1	P38398-1.2	S1377D	Neutral	0.03
BRCA1	P38398-1.2	S1377E	Neutral	0.045
BRCA1	P38398-1.2	S1377F	Neutral	0.144
BRCA1	P38398-1.2	S1377G	Neutral	0.036
BRCA1	P38398-1.2	S1377H	Neutral	0.076
BRCA1	P38398-1.2	S1377I	Neutral	0.116
BRCA1	P38398-1.2	S1377K	Neutral	0.076
BRCA1	P38398-1.2	S1377L	Neutral	0.117
BRCA1	P38398-1.2	S1377M	Neutral	0.085
BRCA1	P38398-1.2	S1377N	Neutral	0.024
BRCA1	P38398-1.2	S1377P	Neutral	0.042
BRCA1	P38398-1.2	S1377Q	Neutral	0.05
BRCA1	P38398-1.2	S1377R	Neutral	0.137
BRCA1	P38398-1.2	S1377T	Neutral	0.022
BRCA1	P38398-1.2	S1377V	Neutral	0.08
BRCA1	P38398-1.2	S1377W	Neutral	0.309
BRCA1	P38398-1.2	S1377Y	Neutral	0.163
BRCA1	P38398-1.2	V1378A	Neutral	0.004
BRCA1	P38398-1.2	V1378C	Neutral	0.003
BRCA1	P38398-1.2	V1378D	Neutral	0.006
BRCA1	P38398-1.2	V1378E	Neutral	0.003
BRCA1	P38398-1.2	V1378F	Neutral	0.004
BRCA1	P38398-1.2	V1378G	Neutral	0.016
BRCA1	P38398-1.2	V1378H	Neutral	0.006
BRCA1	P38398-1.2	V1378I	Neutral	0.001
BRCA1	P38398-1.2	V1378K	Neutral	0.006
BRCA1	P38398-1.2	V1378L	Neutral	0.002
BRCA1	P38398-1.2	V1378M	Neutral	0.002
BRCA1	P38398-1.2	V1378N	Neutral	0.005
BRCA1	P38398-1.2	V1378P	Neutral	0.004
BRCA1	P38398-1.2	V1378Q	Neutral	0.004
BRCA1	P38398-1.2	V1378R	Neutral	0.011
BRCA1	P38398-1.2	V1378S	Neutral	0.006
BRCA1	P38398-1.2	V1378T	Neutral	0.002
BRCA1	P38398-1.2	V1378W	Neutral	0.016
BRCA1	P38398-1.2	V1378Y	Neutral	0.005
BRCA1	P38398-1.2	S1379A	Neutral	0.157
BRCA1	P38398-1.2	S1379C	Neutral	0.307
BRCA1	P38398-1.2	S1379D	Neutral	0.257
BRCA1	P38398-1.2	S1379E	Neutral	0.341
BRCA1	P38398-1.2	S1379F	Pathogenic	0.651
BRCA1	P38398-1.2	S1379G	Neutral	0.291
BRCA1	P38398-1.2	S1379H	Neutral	0.479
BRCA1	P38398-1.2	S1379I	Pathogenic	0.594
BRCA1	P38398-1.2	S1379K	Neutral	0.478
BRCA1	P38398-1.2	S1379L	Pathogenic	0.594
BRCA1	P38398-1.2	S1379M	Pathogenic	0.507
BRCA1	P38398-1.2	S1379N	Neutral	0.212
BRCA1	P38398-1.2	S1379P	Neutral	0.328
BRCA1	P38398-1.2	S1379Q	Neutral	0.368
BRCA1	P38398-1.2	S1379R	Pathogenic	0.638
BRCA1	P38398-1.2	S1379T	Neutral	0.202
BRCA1	P38398-1.2	S1379V	Neutral	0.492
BRCA1	P38398-1.2	S1379W	Pathogenic	0.832
BRCA1	P38398-1.2	S1379Y	Pathogenic	0.684
BRCA1	P38398-1.2	E1380A	Neutral	0.088
BRCA1	P38398-1.2	E1380C	Neutral	0.156
BRCA1	P38398-1.2	E1380D	Neutral	0.019
BRCA1	P38398-1.2	E1380F	Neutral	0.119
BRCA1	P38398-1.2	E1380G	Neutral	0.175
BRCA1	P38398-1.2	E1380H	Neutral	0.031
BRCA1	P38398-1.2	E1380I	Neutral	0.096
BRCA1	P38398-1.2	E1380K	Neutral	0.032
BRCA1	P38398-1.2	E1380L	Neutral	0.096
BRCA1	P38398-1.2	E1380M	Neutral	0.069
BRCA1	P38398-1.2	E1380N	Neutral	0.034
BRCA1	P38398-1.2	E1380P	Neutral	0.054
BRCA1	P38398-1.2	E1380Q	Neutral	0.014
BRCA1	P38398-1.2	E1380R	Neutral	0.059
BRCA1	P38398-1.2	E1380S	Neutral	0.056
BRCA1	P38398-1.2	E1380T	Neutral	0.051
BRCA1	P38398-1.2	E1380V	Neutral	0.055
BRCA1	P38398-1.2	E1380W	Neutral	0.2
BRCA1	P38398-1.2	E1380Y	Neutral	0.099
BRCA1	P38398-1.2	D1381A	Neutral	0.076
BRCA1	P38398-1.2	D1381C	Neutral	0.071
BRCA1	P38398-1.2	D1381E	Neutral	0.017
BRCA1	P38398-1.2	D1381F	Neutral	0.152
BRCA1	P38398-1.2	D1381G	Neutral	0.081
BRCA1	P38398-1.2	D1381H	Neutral	0.058
BRCA1	P38398-1.2	D1381I	Neutral	0.123
BRCA1	P38398-1.2	D1381K	Neutral	0.083
BRCA1	P38398-1.2	D1381L	Neutral	0.169
BRCA1	P38398-1.2	D1381M	Neutral	0.124
BRCA1	P38398-1.2	D1381N	Neutral	0.018
BRCA1	P38398-1.2	D1381P	Neutral	0.033
BRCA1	P38398-1.2	D1381Q	Neutral	0.038
BRCA1	P38398-1.2	D1381R	Neutral	0.148
BRCA1	P38398-1.2	D1381S	Neutral	0.034
BRCA1	P38398-1.2	D1381T	Neutral	0.034
BRCA1	P38398-1.2	D1381V	Neutral	0.085
BRCA1	P38398-1.2	D1381W	Neutral	0.323
BRCA1	P38398-1.2	D1381Y	Neutral	0.172
BRCA1	P38398-1.2	C1382A	Neutral	0.054
BRCA1	P38398-1.2	C1382D	Neutral	0.109
BRCA1	P38398-1.2	C1382E	Neutral	0.209
BRCA1	P38398-1.2	C1382F	Neutral	0.187
BRCA1	P38398-1.2	C1382G	Neutral	0.205
BRCA1	P38398-1.2	C1382H	Neutral	0.185
BRCA1	P38398-1.2	C1382I	Neutral	0.111
BRCA1	P38398-1.2	C1382K	Neutral	0.245
BRCA1	P38398-1.2	C1382L	Neutral	0.112
BRCA1	P38398-1.2	C1382M	Neutral	0.112
BRCA1	P38398-1.2	C1382N	Neutral	0.121
BRCA1	P38398-1.2	C1382P	Neutral	0.11
BRCA1	P38398-1.2	C1382Q	Neutral	0.171
BRCA1	P38398-1.2	C1382R	Neutral	0.302
BRCA1	P38398-1.2	C1382S	Neutral	0.067
BRCA1	P38398-1.2	C1382T	Neutral	0.059
BRCA1	P38398-1.2	C1382V	Neutral	0.077
BRCA1	P38398-1.2	C1382W	Neutral	0.298
BRCA1	P38398-1.2	C1382Y	Neutral	0.211
BRCA1	P38398-1.2	S1383A	Neutral	0.186
BRCA1	P38398-1.2	S1383C	Neutral	0.352
BRCA1	P38398-1.2	S1383D	Neutral	0.298
BRCA1	P38398-1.2	S1383E	Neutral	0.388
BRCA1	P38398-1.2	S1383F	Pathogenic	0.696
BRCA1	P38398-1.2	S1383G	Neutral	0.335
BRCA1	P38398-1.2	S1383H	Pathogenic	0.53
BRCA1	P38398-1.2	S1383I	Pathogenic	0.642
BRCA1	P38398-1.2	S1383K	Pathogenic	0.529
BRCA1	P38398-1.2	S1383L	Pathogenic	0.642
BRCA1	P38398-1.2	S1383M	Pathogenic	0.557
BRCA1	P38398-1.2	S1383N	Neutral	0.249
BRCA1	P38398-1.2	S1383P	Neutral	0.374
BRCA1	P38398-1.2	S1383Q	Neutral	0.417
BRCA1	P38398-1.2	S1383R	Pathogenic	0.683
BRCA1	P38398-1.2	S1383T	Neutral	0.237
BRCA1	P38398-1.2	S1383V	Pathogenic	0.543
BRCA1	P38398-1.2	S1383W	Pathogenic	0.859
BRCA1	P38398-1.2	S1383Y	Pathogenic	0.727
BRCA1	P38398-1.2	G1384A	Neutral	0.058
BRCA1	P38398-1.2	G1384C	Neutral	0.217
BRCA1	P38398-1.2	G1384D	Neutral	0.13
BRCA1	P38398-1.2	G1384E	Neutral	0.244
BRCA1	P38398-1.2	G1384F	Neutral	0.447
BRCA1	P38398-1.2	G1384H	Neutral	0.285
BRCA1	P38398-1.2	G1384I	Neutral	0.477
BRCA1	P38398-1.2	G1384K	Neutral	0.364
BRCA1	P38398-1.2	G1384L	Neutral	0.478
BRCA1	P38398-1.2	G1384M	Neutral	0.391
BRCA1	P38398-1.2	G1384N	Neutral	0.105
BRCA1	P38398-1.2	G1384P	Neutral	0.174
BRCA1	P38398-1.2	G1384Q	Neutral	0.267
BRCA1	P38398-1.2	G1384R	Neutral	0.433
BRCA1	P38398-1.2	G1384S	Neutral	0.066
BRCA1	P38398-1.2	G1384T	Neutral	0.186
BRCA1	P38398-1.2	G1384V	Neutral	0.296
BRCA1	P38398-1.2	G1384W	Pathogenic	0.509
BRCA1	P38398-1.2	G1384Y	Neutral	0.484
BRCA1	P38398-1.2	L1385A	Pathogenic	0.581
BRCA1	P38398-1.2	L1385C	Neutral	0.48
BRCA1	P38398-1.2	L1385D	Pathogenic	0.704
BRCA1	P38398-1.2	L1385E	Pathogenic	0.526
BRCA1	P38398-1.2	L1385F	Neutral	0.263
BRCA1	P38398-1.2	L1385G	Pathogenic	0.862
BRCA1	P38398-1.2	L1385H	Neutral	0.48
BRCA1	P38398-1.2	L1385I	Neutral	0.119
BRCA1	P38398-1.2	L1385K	Neutral	0.412
BRCA1	P38398-1.2	L1385M	Neutral	0.118
BRCA1	P38398-1.2	L1385N	Pathogenic	0.597
BRCA1	P38398-1.2	L1385P	Pathogenic	0.635
BRCA1	P38398-1.2	L1385Q	Neutral	0.41
BRCA1	P38398-1.2	L1385R	Neutral	0.483
BRCA1	P38398-1.2	L1385S	Pathogenic	0.635
BRCA1	P38398-1.2	L1385T	Neutral	0.438
BRCA1	P38398-1.2	L1385V	Neutral	0.227
BRCA1	P38398-1.2	L1385W	Pathogenic	0.577
BRCA1	P38398-1.2	L1385Y	Neutral	0.366
BRCA1	P38398-1.2	S1386A	Neutral	0.261
BRCA1	P38398-1.2	S1386C	Neutral	0.457
BRCA1	P38398-1.2	S1386D	Neutral	0.397
BRCA1	P38398-1.2	S1386E	Neutral	0.496
BRCA1	P38398-1.2	S1386F	Pathogenic	0.78
BRCA1	P38398-1.2	S1386G	Neutral	0.438
BRCA1	P38398-1.2	S1386H	Pathogenic	0.635
BRCA1	P38398-1.2	S1386I	Pathogenic	0.735
BRCA1	P38398-1.2	S1386K	Pathogenic	0.635
BRCA1	P38398-1.2	S1386L	Pathogenic	0.735
BRCA1	P38398-1.2	S1386M	Pathogenic	0.661
BRCA1	P38398-1.2	S1386N	Neutral	0.339
BRCA1	P38398-1.2	S1386P	Neutral	0.481
BRCA1	P38398-1.2	S1386Q	Pathogenic	0.526
BRCA1	P38398-1.2	S1386R	Pathogenic	0.77
BRCA1	P38398-1.2	S1386T	Neutral	0.325
BRCA1	P38398-1.2	S1386V	Pathogenic	0.648
BRCA1	P38398-1.2	S1386W	Pathogenic	0.904
BRCA1	P38398-1.2	S1386Y	Pathogenic	0.804
BRCA1	P38398-1.2	S1387A	Neutral	0.215
BRCA1	P38398-1.2	S1387C	Neutral	0.395
BRCA1	P38398-1.2	S1387D	Neutral	0.338
BRCA1	P38398-1.2	S1387E	Neutral	0.433
BRCA1	P38398-1.2	S1387F	Pathogenic	0.733
BRCA1	P38398-1.2	S1387G	Neutral	0.377
BRCA1	P38398-1.2	S1387H	Pathogenic	0.575
BRCA1	P38398-1.2	S1387I	Pathogenic	0.683
BRCA1	P38398-1.2	S1387K	Pathogenic	0.575
BRCA1	P38398-1.2	S1387L	Pathogenic	0.683
BRCA1	P38398-1.2	S1387M	Pathogenic	0.602
BRCA1	P38398-1.2	S1387N	Neutral	0.284
BRCA1	P38398-1.2	S1387P	Neutral	0.418
BRCA1	P38398-1.2	S1387Q	Neutral	0.462
BRCA1	P38398-1.2	S1387R	Pathogenic	0.722
BRCA1	P38398-1.2	S1387T	Neutral	0.272
BRCA1	P38398-1.2	S1387V	Pathogenic	0.588
BRCA1	P38398-1.2	S1387W	Pathogenic	0.88
BRCA1	P38398-1.2	S1387Y	Pathogenic	0.762
BRCA1	P38398-1.2	Q1388A	Pathogenic	0.863
BRCA1	P38398-1.2	Q1388C	Pathogenic	0.894
BRCA1	P38398-1.2	Q1388D	Pathogenic	0.719
BRCA1	P38398-1.2	Q1388E	Neutral	0.454
BRCA1	P38398-1.2	Q1388F	Pathogenic	0.877
BRCA1	P38398-1.2	Q1388G	Pathogenic	0.933
BRCA1	P38398-1.2	Q1388H	Pathogenic	0.628
BRCA1	P38398-1.2	Q1388I	Pathogenic	0.848
BRCA1	P38398-1.2	Q1388K	Pathogenic	0.629
BRCA1	P38398-1.2	Q1388L	Pathogenic	0.795
BRCA1	P38398-1.2	Q1388M	Pathogenic	0.654
BRCA1	P38398-1.2	Q1388N	Pathogenic	0.697
BRCA1	P38398-1.2	Q1388P	Pathogenic	0.789
BRCA1	P38398-1.2	Q1388R	Pathogenic	0.694
BRCA1	P38398-1.2	Q1388S	Pathogenic	0.794
BRCA1	P38398-1.2	Q1388T	Pathogenic	0.779
BRCA1	P38398-1.2	Q1388V	Pathogenic	0.793
BRCA1	P38398-1.2	Q1388W	Pathogenic	0.901
BRCA1	P38398-1.2	Q1388Y	Pathogenic	0.799
BRCA1	P38398-1.2	S1389A	Neutral	0.289
BRCA1	P38398-1.2	S1389C	Neutral	0.493
BRCA1	P38398-1.2	S1389D	Neutral	0.432
BRCA1	P38398-1.2	S1389E	Pathogenic	0.532
BRCA1	P38398-1.2	S1389F	Pathogenic	0.804
BRCA1	P38398-1.2	S1389G	Neutral	0.474
BRCA1	P38398-1.2	S1389H	Pathogenic	0.668
BRCA1	P38398-1.2	S1389I	Pathogenic	0.762
BRCA1	P38398-1.2	S1389K	Pathogenic	0.668
BRCA1	P38398-1.2	S1389L	Pathogenic	0.763
BRCA1	P38398-1.2	S1389M	Pathogenic	0.693
BRCA1	P38398-1.2	S1389N	Neutral	0.372
BRCA1	P38398-1.2	S1389P	Pathogenic	0.517
BRCA1	P38398-1.2	S1389Q	Pathogenic	0.561
BRCA1	P38398-1.2	S1389R	Pathogenic	0.794
BRCA1	P38398-1.2	S1389T	Neutral	0.358
BRCA1	P38398-1.2	S1389V	Pathogenic	0.68
BRCA1	P38398-1.2	S1389W	Pathogenic	0.916
BRCA1	P38398-1.2	S1389Y	Pathogenic	0.826
BRCA1	P38398-1.2	D1390A	Neutral	0.065
BRCA1	P38398-1.2	D1390C	Neutral	0.061
BRCA1	P38398-1.2	D1390E	Neutral	0.014
BRCA1	P38398-1.2	D1390F	Neutral	0.133
BRCA1	P38398-1.2	D1390G	Neutral	0.069
BRCA1	P38398-1.2	D1390H	Neutral	0.05
BRCA1	P38398-1.2	D1390I	Neutral	0.107
BRCA1	P38398-1.2	D1390K	Neutral	0.072
BRCA1	P38398-1.2	D1390L	Neutral	0.147
BRCA1	P38398-1.2	D1390M	Neutral	0.108
BRCA1	P38398-1.2	D1390N	Neutral	0.015
BRCA1	P38398-1.2	D1390P	Neutral	0.028
BRCA1	P38398-1.2	D1390Q	Neutral	0.032
BRCA1	P38398-1.2	D1390R	Neutral	0.129
BRCA1	P38398-1.2	D1390S	Neutral	0.029
BRCA1	P38398-1.2	D1390T	Neutral	0.029
BRCA1	P38398-1.2	D1390V	Neutral	0.074
BRCA1	P38398-1.2	D1390W	Neutral	0.289
BRCA1	P38398-1.2	D1390Y	Neutral	0.151
BRCA1	P38398-1.2	I1391A	Pathogenic	0.854
BRCA1	P38398-1.2	I1391C	Pathogenic	0.795
BRCA1	P38398-1.2	I1391D	Pathogenic	0.874
BRCA1	P38398-1.2	I1391E	Pathogenic	0.824
BRCA1	P38398-1.2	I1391F	Pathogenic	0.601
BRCA1	P38398-1.2	I1391G	Pathogenic	0.963
BRCA1	P38398-1.2	I1391H	Pathogenic	0.795
BRCA1	P38398-1.2	I1391K	Pathogenic	0.809
BRCA1	P38398-1.2	I1391L	Neutral	0.362
BRCA1	P38398-1.2	I1391M	Neutral	0.447
BRCA1	P38398-1.2	I1391N	Pathogenic	0.862
BRCA1	P38398-1.2	I1391P	Pathogenic	0.88
BRCA1	P38398-1.2	I1391Q	Pathogenic	0.808
BRCA1	P38398-1.2	I1391R	Pathogenic	0.85
BRCA1	P38398-1.2	I1391S	Pathogenic	0.88
BRCA1	P38398-1.2	I1391T	Pathogenic	0.766
BRCA1	P38398-1.2	I1391V	Neutral	0.373
BRCA1	P38398-1.2	I1391W	Pathogenic	0.892
BRCA1	P38398-1.2	I1391Y	Pathogenic	0.709
BRCA1	P38398-1.2	L1392A	Pathogenic	0.86
BRCA1	P38398-1.2	L1392C	Pathogenic	0.803
BRCA1	P38398-1.2	L1392D	Pathogenic	0.913
BRCA1	P38398-1.2	L1392E	Pathogenic	0.831
BRCA1	P38398-1.2	L1392F	Pathogenic	0.611
BRCA1	P38398-1.2	L1392G	Pathogenic	0.965
BRCA1	P38398-1.2	L1392H	Pathogenic	0.803
BRCA1	P38398-1.2	L1392I	Neutral	0.373
BRCA1	P38398-1.2	L1392K	Pathogenic	0.756
BRCA1	P38398-1.2	L1392M	Neutral	0.371
BRCA1	P38398-1.2	L1392N	Pathogenic	0.868
BRCA1	P38398-1.2	L1392P	Pathogenic	0.885
BRCA1	P38398-1.2	L1392Q	Pathogenic	0.755
BRCA1	P38398-1.2	L1392R	Pathogenic	0.805
BRCA1	P38398-1.2	L1392S	Pathogenic	0.885
BRCA1	P38398-1.2	L1392T	Pathogenic	0.775
BRCA1	P38398-1.2	L1392V	Pathogenic	0.564
BRCA1	P38398-1.2	L1392W	Pathogenic	0.857
BRCA1	P38398-1.2	L1392Y	Pathogenic	0.719
BRCA1	P38398-1.2	T1393A	Pathogenic	0.651
BRCA1	P38398-1.2	T1393C	Pathogenic	0.635
BRCA1	P38398-1.2	T1393D	Pathogenic	0.607
BRCA1	P38398-1.2	T1393E	Pathogenic	0.679
BRCA1	P38398-1.2	T1393F	Pathogenic	0.843
BRCA1	P38398-1.2	T1393G	Pathogenic	0.854
BRCA1	P38398-1.2	T1393H	Pathogenic	0.791
BRCA1	P38398-1.2	T1393I	Pathogenic	0.745
BRCA1	P38398-1.2	T1393K	Pathogenic	0.789
BRCA1	P38398-1.2	T1393L	Pathogenic	0.745
BRCA1	P38398-1.2	T1393M	Pathogenic	0.747
BRCA1	P38398-1.2	T1393N	Pathogenic	0.524
BRCA1	P38398-1.2	T1393P	Pathogenic	0.615
BRCA1	P38398-1.2	T1393Q	Pathogenic	0.705
BRCA1	P38398-1.2	T1393R	Pathogenic	0.833
BRCA1	P38398-1.2	T1393S	Pathogenic	0.531
BRCA1	P38398-1.2	T1393V	Pathogenic	0.573
BRCA1	P38398-1.2	T1393W	Pathogenic	0.908
BRCA1	P38398-1.2	T1393Y	Pathogenic	0.862
BRCA1	P38398-1.2	T1394A	Pathogenic	0.512
BRCA1	P38398-1.2	T1394C	Neutral	0.494
BRCA1	P38398-1.2	T1394D	Neutral	0.465
BRCA1	P38398-1.2	T1394E	Pathogenic	0.544
BRCA1	P38398-1.2	T1394F	Pathogenic	0.751
BRCA1	P38398-1.2	T1394G	Pathogenic	0.768
BRCA1	P38398-1.2	T1394H	Pathogenic	0.68
BRCA1	P38398-1.2	T1394I	Pathogenic	0.621
BRCA1	P38398-1.2	T1394K	Pathogenic	0.678
BRCA1	P38398-1.2	T1394L	Pathogenic	0.622
BRCA1	P38398-1.2	T1394M	Pathogenic	0.624
BRCA1	P38398-1.2	T1394N	Neutral	0.383
BRCA1	P38398-1.2	T1394P	Neutral	0.474
BRCA1	P38398-1.2	T1394Q	Pathogenic	0.573
BRCA1	P38398-1.2	T1394R	Pathogenic	0.738
BRCA1	P38398-1.2	T1394S	Neutral	0.389
BRCA1	P38398-1.2	T1394V	Neutral	0.431
BRCA1	P38398-1.2	T1394W	Pathogenic	0.848
BRCA1	P38398-1.2	T1394Y	Pathogenic	0.778
BRCA1	P38398-1.2	Q1395A	Pathogenic	0.858
BRCA1	P38398-1.2	Q1395C	Pathogenic	0.89
BRCA1	P38398-1.2	Q1395D	Pathogenic	0.711
BRCA1	P38398-1.2	Q1395E	Neutral	0.444
BRCA1	P38398-1.2	Q1395F	Pathogenic	0.872
BRCA1	P38398-1.2	Q1395G	Pathogenic	0.93
BRCA1	P38398-1.2	Q1395H	Pathogenic	0.618
BRCA1	P38398-1.2	Q1395I	Pathogenic	0.842
BRCA1	P38398-1.2	Q1395K	Pathogenic	0.619
BRCA1	P38398-1.2	Q1395L	Pathogenic	0.788
BRCA1	P38398-1.2	Q1395M	Pathogenic	0.644
BRCA1	P38398-1.2	Q1395N	Pathogenic	0.688
BRCA1	P38398-1.2	Q1395P	Pathogenic	0.782
BRCA1	P38398-1.2	Q1395R	Pathogenic	0.685
BRCA1	P38398-1.2	Q1395S	Pathogenic	0.787
BRCA1	P38398-1.2	Q1395T	Pathogenic	0.772
BRCA1	P38398-1.2	Q1395V	Pathogenic	0.786
BRCA1	P38398-1.2	Q1395W	Pathogenic	0.897
BRCA1	P38398-1.2	Q1395Y	Pathogenic	0.793
BRCA1	P38398-1.2	Q1396A	Pathogenic	0.86
BRCA1	P38398-1.2	Q1396C	Pathogenic	0.891
BRCA1	P38398-1.2	Q1396D	Pathogenic	0.714
BRCA1	P38398-1.2	Q1396E	Neutral	0.447
BRCA1	P38398-1.2	Q1396F	Pathogenic	0.874
BRCA1	P38398-1.2	Q1396G	Pathogenic	0.931
BRCA1	P38398-1.2	Q1396H	Pathogenic	0.622
BRCA1	P38398-1.2	Q1396I	Pathogenic	0.844
BRCA1	P38398-1.2	Q1396K	Pathogenic	0.623
BRCA1	P38398-1.2	Q1396L	Pathogenic	0.79
BRCA1	P38398-1.2	Q1396M	Pathogenic	0.648
BRCA1	P38398-1.2	Q1396N	Pathogenic	0.691
BRCA1	P38398-1.2	Q1396P	Pathogenic	0.785
BRCA1	P38398-1.2	Q1396R	Pathogenic	0.688
BRCA1	P38398-1.2	Q1396S	Pathogenic	0.789
BRCA1	P38398-1.2	Q1396T	Pathogenic	0.775
BRCA1	P38398-1.2	Q1396V	Pathogenic	0.788
BRCA1	P38398-1.2	Q1396W	Pathogenic	0.899
BRCA1	P38398-1.2	Q1396Y	Pathogenic	0.795
BRCA1	P38398-1.2	R1397A	Pathogenic	0.733
BRCA1	P38398-1.2	R1397C	Pathogenic	0.787
BRCA1	P38398-1.2	R1397D	Pathogenic	0.703
BRCA1	P38398-1.2	R1397E	Neutral	0.434
BRCA1	P38398-1.2	R1397F	Pathogenic	0.55
BRCA1	P38398-1.2	R1397G	Pathogenic	0.859
BRCA1	P38398-1.2	R1397H	Neutral	0.382
BRCA1	P38398-1.2	R1397I	Pathogenic	0.609
BRCA1	P38398-1.2	R1397K	Neutral	0.173
BRCA1	P38398-1.2	R1397L	Pathogenic	0.521
BRCA1	P38398-1.2	R1397M	Neutral	0.432
BRCA1	P38398-1.2	R1397N	Pathogenic	0.505
BRCA1	P38398-1.2	R1397P	Pathogenic	0.702
BRCA1	P38398-1.2	R1397Q	Neutral	0.321
BRCA1	P38398-1.2	R1397S	Pathogenic	0.708
BRCA1	P38398-1.2	R1397T	Pathogenic	0.607
BRCA1	P38398-1.2	R1397V	Pathogenic	0.706
BRCA1	P38398-1.2	R1397W	Pathogenic	0.559
BRCA1	P38398-1.2	R1397Y	Neutral	0.43
BRCA1	P38398-1.2	D1398A	Neutral	0.233
BRCA1	P38398-1.2	D1398C	Neutral	0.221
BRCA1	P38398-1.2	D1398E	Neutral	0.059
BRCA1	P38398-1.2	D1398F	Neutral	0.399
BRCA1	P38398-1.2	D1398G	Neutral	0.245
BRCA1	P38398-1.2	D1398H	Neutral	0.185
BRCA1	P38398-1.2	D1398I	Neutral	0.342
BRCA1	P38398-1.2	D1398K	Neutral	0.251
BRCA1	P38398-1.2	D1398L	Neutral	0.428
BRCA1	P38398-1.2	D1398M	Neutral	0.344
BRCA1	P38398-1.2	D1398N	Neutral	0.064
BRCA1	P38398-1.2	D1398P	Neutral	0.112
BRCA1	P38398-1.2	D1398Q	Neutral	0.127
BRCA1	P38398-1.2	D1398R	Neutral	0.391
BRCA1	P38398-1.2	D1398S	Neutral	0.114
BRCA1	P38398-1.2	D1398T	Neutral	0.115
BRCA1	P38398-1.2	D1398V	Neutral	0.256
BRCA1	P38398-1.2	D1398W	Pathogenic	0.638
BRCA1	P38398-1.2	D1398Y	Neutral	0.435
BRCA1	P38398-1.2	T1399A	Neutral	0.433
BRCA1	P38398-1.2	T1399C	Neutral	0.416
BRCA1	P38398-1.2	T1399D	Neutral	0.388
BRCA1	P38398-1.2	T1399E	Neutral	0.465
BRCA1	P38398-1.2	T1399F	Pathogenic	0.687
BRCA1	P38398-1.2	T1399G	Pathogenic	0.707
BRCA1	P38398-1.2	T1399H	Pathogenic	0.608
BRCA1	P38398-1.2	T1399I	Pathogenic	0.545
BRCA1	P38398-1.2	T1399K	Pathogenic	0.606
BRCA1	P38398-1.2	T1399L	Pathogenic	0.545
BRCA1	P38398-1.2	T1399M	Pathogenic	0.547
BRCA1	P38398-1.2	T1399N	Neutral	0.311
BRCA1	P38398-1.2	T1399P	Neutral	0.396
BRCA1	P38398-1.2	T1399Q	Neutral	0.494
BRCA1	P38398-1.2	T1399R	Pathogenic	0.672
BRCA1	P38398-1.2	T1399S	Neutral	0.317
BRCA1	P38398-1.2	T1399V	Neutral	0.355
BRCA1	P38398-1.2	T1399W	Pathogenic	0.802
BRCA1	P38398-1.2	T1399Y	Pathogenic	0.718
BRCA1	P38398-1.2	M1400A	Pathogenic	0.628
BRCA1	P38398-1.2	M1400C	Pathogenic	0.528
BRCA1	P38398-1.2	M1400D	Pathogenic	0.667
BRCA1	P38398-1.2	M1400E	Neutral	0.484
BRCA1	P38398-1.2	M1400F	Neutral	0.298
BRCA1	P38398-1.2	M1400G	Pathogenic	0.841
BRCA1	P38398-1.2	M1400H	Neutral	0.438
BRCA1	P38398-1.2	M1400I	Neutral	0.188
BRCA1	P38398-1.2	M1400K	Neutral	0.372
BRCA1	P38398-1.2	M1400L	Neutral	0.139
BRCA1	P38398-1.2	M1400N	Pathogenic	0.556
BRCA1	P38398-1.2	M1400P	Pathogenic	0.595
BRCA1	P38398-1.2	M1400Q	Neutral	0.29
BRCA1	P38398-1.2	M1400R	Neutral	0.441
BRCA1	P38398-1.2	M1400S	Pathogenic	0.594
BRCA1	P38398-1.2	M1400T	Neutral	0.486
BRCA1	P38398-1.2	M1400V	Neutral	0.263
BRCA1	P38398-1.2	M1400W	Pathogenic	0.53
BRCA1	P38398-1.2	M1400Y	Neutral	0.413
BRCA1	P38398-1.2	Q1401A	Neutral	0.446
BRCA1	P38398-1.2	Q1401C	Pathogenic	0.519
BRCA1	P38398-1.2	Q1401D	Neutral	0.247
BRCA1	P38398-1.2	Q1401E	Neutral	0.096
BRCA1	P38398-1.2	Q1401F	Neutral	0.476
BRCA1	P38398-1.2	Q1401G	Pathogenic	0.64
BRCA1	P38398-1.2	Q1401H	Neutral	0.178
BRCA1	P38398-1.2	Q1401I	Neutral	0.416
BRCA1	P38398-1.2	Q1401K	Neutral	0.178
BRCA1	P38398-1.2	Q1401L	Neutral	0.332
BRCA1	P38398-1.2	Q1401M	Neutral	0.195
BRCA1	P38398-1.2	Q1401N	Neutral	0.228
BRCA1	P38398-1.2	Q1401P	Neutral	0.324
BRCA1	P38398-1.2	Q1401R	Neutral	0.225
BRCA1	P38398-1.2	Q1401S	Neutral	0.33
BRCA1	P38398-1.2	Q1401T	Neutral	0.311
BRCA1	P38398-1.2	Q1401V	Neutral	0.329
BRCA1	P38398-1.2	Q1401W	Pathogenic	0.539
BRCA1	P38398-1.2	Q1401Y	Neutral	0.338
BRCA1	P38398-1.2	H1402A	Neutral	0.379
BRCA1	P38398-1.2	H1402C	Neutral	0.362
BRCA1	P38398-1.2	H1402D	Neutral	0.197
BRCA1	P38398-1.2	H1402E	Neutral	0.103
BRCA1	P38398-1.2	H1402F	Neutral	0.162
BRCA1	P38398-1.2	H1402G	Neutral	0.482
BRCA1	P38398-1.2	H1402I	Neutral	0.239
BRCA1	P38398-1.2	H1402K	Neutral	0.164
BRCA1	P38398-1.2	H1402L	Neutral	0.239
BRCA1	P38398-1.2	H1402M	Neutral	0.181
BRCA1	P38398-1.2	H1402N	Neutral	0.096
BRCA1	P38398-1.2	H1402P	Neutral	0.266
BRCA1	P38398-1.2	H1402Q	Neutral	0.094
BRCA1	P38398-1.2	H1402R	Neutral	0.154
BRCA1	P38398-1.2	H1402S	Neutral	0.271
BRCA1	P38398-1.2	H1402T	Neutral	0.255
BRCA1	P38398-1.2	H1402V	Neutral	0.271
BRCA1	P38398-1.2	H1402W	Neutral	0.34
BRCA1	P38398-1.2	H1402Y	Neutral	0.07
BRCA1	P38398-1.2	N1403A	Pathogenic	0.829
BRCA1	P38398-1.2	N1403C	Pathogenic	0.818
BRCA1	P38398-1.2	N1403D	Neutral	0.491
BRCA1	P38398-1.2	N1403E	Pathogenic	0.625
BRCA1	P38398-1.2	N1403F	Pathogenic	0.894
BRCA1	P38398-1.2	N1403G	Pathogenic	0.782
BRCA1	P38398-1.2	N1403H	Pathogenic	0.582
BRCA1	P38398-1.2	N1403I	Pathogenic	0.869
BRCA1	P38398-1.2	N1403K	Pathogenic	0.747
BRCA1	P38398-1.2	N1403L	Pathogenic	0.869
BRCA1	P38398-1.2	N1403M	Pathogenic	0.823
BRCA1	P38398-1.2	N1403P	Pathogenic	0.742
BRCA1	P38398-1.2	N1403Q	Pathogenic	0.649
BRCA1	P38398-1.2	N1403R	Pathogenic	0.797
BRCA1	P38398-1.2	N1403S	Pathogenic	0.588
BRCA1	P38398-1.2	N1403T	Pathogenic	0.567
BRCA1	P38398-1.2	N1403V	Pathogenic	0.814
BRCA1	P38398-1.2	N1403W	Pathogenic	0.957
BRCA1	P38398-1.2	N1403Y	Pathogenic	0.872
BRCA1	P38398-1.2	L1404A	Pathogenic	0.84
BRCA1	P38398-1.2	L1404C	Pathogenic	0.777
BRCA1	P38398-1.2	L1404D	Pathogenic	0.9
BRCA1	P38398-1.2	L1404E	Pathogenic	0.807
BRCA1	P38398-1.2	L1404F	Pathogenic	0.573
BRCA1	P38398-1.2	L1404G	Pathogenic	0.959
BRCA1	P38398-1.2	L1404H	Pathogenic	0.777
BRCA1	P38398-1.2	L1404I	Neutral	0.337
BRCA1	P38398-1.2	L1404K	Pathogenic	0.726
BRCA1	P38398-1.2	L1404M	Neutral	0.335
BRCA1	P38398-1.2	L1404N	Pathogenic	0.848
BRCA1	P38398-1.2	L1404P	Pathogenic	0.868
BRCA1	P38398-1.2	L1404Q	Pathogenic	0.724
BRCA1	P38398-1.2	L1404R	Pathogenic	0.779
BRCA1	P38398-1.2	L1404S	Pathogenic	0.868
BRCA1	P38398-1.2	L1404T	Pathogenic	0.746
BRCA1	P38398-1.2	L1404V	Pathogenic	0.525
BRCA1	P38398-1.2	L1404W	Pathogenic	0.837
BRCA1	P38398-1.2	L1404Y	Pathogenic	0.686
BRCA1	P38398-1.2	I1405A	Neutral	0.169
BRCA1	P38398-1.2	I1405C	Neutral	0.119
BRCA1	P38398-1.2	I1405D	Neutral	0.195
BRCA1	P38398-1.2	I1405E	Neutral	0.14
BRCA1	P38398-1.2	I1405F	Neutral	0.05
BRCA1	P38398-1.2	I1405G	Neutral	0.479
BRCA1	P38398-1.2	I1405H	Neutral	0.119
BRCA1	P38398-1.2	I1405K	Neutral	0.129
BRCA1	P38398-1.2	I1405L	Neutral	0.019
BRCA1	P38398-1.2	I1405M	Neutral	0.027
BRCA1	P38398-1.2	I1405N	Neutral	0.179
BRCA1	P38398-1.2	I1405P	Neutral	0.203
BRCA1	P38398-1.2	I1405Q	Neutral	0.128
BRCA1	P38398-1.2	I1405R	Neutral	0.165
BRCA1	P38398-1.2	I1405S	Neutral	0.203
BRCA1	P38398-1.2	I1405T	Neutral	0.102
BRCA1	P38398-1.2	I1405V	Neutral	0.02
BRCA1	P38398-1.2	I1405W	Neutral	0.224
BRCA1	P38398-1.2	I1405Y	Neutral	0.078
BRCA1	P38398-1.2	K1406A	Pathogenic	0.654
BRCA1	P38398-1.2	K1406C	Pathogenic	0.717
BRCA1	P38398-1.2	K1406D	Pathogenic	0.531
BRCA1	P38398-1.2	K1406E	Neutral	0.268
BRCA1	P38398-1.2	K1406F	Neutral	0.457
BRCA1	P38398-1.2	K1406G	Pathogenic	0.807
BRCA1	P38398-1.2	K1406H	Neutral	0.38
BRCA1	P38398-1.2	K1406I	Pathogenic	0.518
BRCA1	P38398-1.2	K1406L	Neutral	0.428
BRCA1	P38398-1.2	K1406M	Neutral	0.344
BRCA1	P38398-1.2	K1406N	Neutral	0.413
BRCA1	P38398-1.2	K1406P	Pathogenic	0.53
BRCA1	P38398-1.2	K1406Q	Neutral	0.245
BRCA1	P38398-1.2	K1406R	Neutral	0.161
BRCA1	P38398-1.2	K1406S	Pathogenic	0.537
BRCA1	P38398-1.2	K1406T	Pathogenic	0.515
BRCA1	P38398-1.2	K1406V	Pathogenic	0.535
BRCA1	P38398-1.2	K1406W	Pathogenic	0.608
BRCA1	P38398-1.2	K1406Y	Neutral	0.404
BRCA1	P38398-1.2	L1407A	Pathogenic	0.513
BRCA1	P38398-1.2	L1407C	Neutral	0.412
BRCA1	P38398-1.2	L1407D	Pathogenic	0.644
BRCA1	P38398-1.2	L1407E	Neutral	0.458
BRCA1	P38398-1.2	L1407F	Neutral	0.213
BRCA1	P38398-1.2	L1407G	Pathogenic	0.827
BRCA1	P38398-1.2	L1407H	Neutral	0.412
BRCA1	P38398-1.2	L1407I	Neutral	0.093
BRCA1	P38398-1.2	L1407K	Neutral	0.348
BRCA1	P38398-1.2	L1407M	Neutral	0.092
BRCA1	P38398-1.2	L1407N	Pathogenic	0.53
BRCA1	P38398-1.2	L1407P	Pathogenic	0.569
BRCA1	P38398-1.2	L1407Q	Neutral	0.346
BRCA1	P38398-1.2	L1407R	Neutral	0.416
BRCA1	P38398-1.2	L1407S	Pathogenic	0.569
BRCA1	P38398-1.2	L1407T	Neutral	0.372
BRCA1	P38398-1.2	L1407V	Neutral	0.182
BRCA1	P38398-1.2	L1407W	Pathogenic	0.509
BRCA1	P38398-1.2	L1407Y	Neutral	0.305
BRCA1	P38398-1.2	Q1408A	Neutral	0.436
BRCA1	P38398-1.2	Q1408C	Pathogenic	0.509
BRCA1	P38398-1.2	Q1408D	Neutral	0.24
BRCA1	P38398-1.2	Q1408E	Neutral	0.093
BRCA1	P38398-1.2	Q1408F	Neutral	0.466
BRCA1	P38398-1.2	Q1408G	Pathogenic	0.63
BRCA1	P38398-1.2	Q1408H	Neutral	0.172
BRCA1	P38398-1.2	Q1408I	Neutral	0.406
BRCA1	P38398-1.2	Q1408K	Neutral	0.173
BRCA1	P38398-1.2	Q1408L	Neutral	0.323
BRCA1	P38398-1.2	Q1408M	Neutral	0.188
BRCA1	P38398-1.2	Q1408N	Neutral	0.22
BRCA1	P38398-1.2	Q1408P	Neutral	0.315
BRCA1	P38398-1.2	Q1408R	Neutral	0.218
BRCA1	P38398-1.2	Q1408S	Neutral	0.321
BRCA1	P38398-1.2	Q1408T	Neutral	0.303
BRCA1	P38398-1.2	Q1408V	Neutral	0.32
BRCA1	P38398-1.2	Q1408W	Pathogenic	0.528
BRCA1	P38398-1.2	Q1408Y	Neutral	0.329
BRCA1	P38398-1.2	Q1409A	Pathogenic	0.815
BRCA1	P38398-1.2	Q1409C	Pathogenic	0.855
BRCA1	P38398-1.2	Q1409D	Pathogenic	0.642
BRCA1	P38398-1.2	Q1409E	Neutral	0.368
BRCA1	P38398-1.2	Q1409F	Pathogenic	0.833
BRCA1	P38398-1.2	Q1409G	Pathogenic	0.907
BRCA1	P38398-1.2	Q1409H	Pathogenic	0.541
BRCA1	P38398-1.2	Q1409I	Pathogenic	0.796
BRCA1	P38398-1.2	Q1409K	Pathogenic	0.543
BRCA1	P38398-1.2	Q1409L	Pathogenic	0.731
BRCA1	P38398-1.2	Q1409M	Pathogenic	0.569
BRCA1	P38398-1.2	Q1409N	Pathogenic	0.617
BRCA1	P38398-1.2	Q1409P	Pathogenic	0.724
BRCA1	P38398-1.2	Q1409R	Pathogenic	0.613
BRCA1	P38398-1.2	Q1409S	Pathogenic	0.729
BRCA1	P38398-1.2	Q1409T	Pathogenic	0.712
BRCA1	P38398-1.2	Q1409V	Pathogenic	0.728
BRCA1	P38398-1.2	Q1409W	Pathogenic	0.864
BRCA1	P38398-1.2	Q1409Y	Pathogenic	0.736
BRCA1	P38398-1.2	E1410A	Pathogenic	0.57
BRCA1	P38398-1.2	E1410C	Pathogenic	0.719
BRCA1	P38398-1.2	E1410D	Neutral	0.21
BRCA1	P38398-1.2	E1410F	Pathogenic	0.652
BRCA1	P38398-1.2	E1410G	Pathogenic	0.746
BRCA1	P38398-1.2	E1410H	Neutral	0.308
BRCA1	P38398-1.2	E1410I	Pathogenic	0.594
BRCA1	P38398-1.2	E1410K	Neutral	0.312
BRCA1	P38398-1.2	E1410L	Pathogenic	0.595
BRCA1	P38398-1.2	E1410M	Pathogenic	0.507
BRCA1	P38398-1.2	E1410N	Neutral	0.33
BRCA1	P38398-1.2	E1410P	Neutral	0.441
BRCA1	P38398-1.2	E1410Q	Neutral	0.165
BRCA1	P38398-1.2	E1410R	Neutral	0.466
BRCA1	P38398-1.2	E1410S	Neutral	0.448
BRCA1	P38398-1.2	E1410T	Neutral	0.427
BRCA1	P38398-1.2	E1410V	Neutral	0.447
BRCA1	P38398-1.2	E1410W	Pathogenic	0.776
BRCA1	P38398-1.2	E1410Y	Pathogenic	0.602
BRCA1	P38398-1.2	M1411A	Pathogenic	0.861
BRCA1	P38398-1.2	M1411C	Pathogenic	0.804
BRCA1	P38398-1.2	M1411D	Pathogenic	0.88
BRCA1	P38398-1.2	M1411E	Pathogenic	0.775
BRCA1	P38398-1.2	M1411F	Pathogenic	0.609
BRCA1	P38398-1.2	M1411G	Pathogenic	0.951
BRCA1	P38398-1.2	M1411H	Pathogenic	0.741
BRCA1	P38398-1.2	M1411I	Neutral	0.459
BRCA1	P38398-1.2	M1411K	Pathogenic	0.685
BRCA1	P38398-1.2	M1411L	Neutral	0.371
BRCA1	P38398-1.2	M1411N	Pathogenic	0.821
BRCA1	P38398-1.2	M1411P	Pathogenic	0.843
BRCA1	P38398-1.2	M1411Q	Pathogenic	0.6
BRCA1	P38398-1.2	M1411R	Pathogenic	0.743
BRCA1	P38398-1.2	M1411S	Pathogenic	0.843
BRCA1	P38398-1.2	M1411T	Pathogenic	0.776
BRCA1	P38398-1.2	M1411V	Pathogenic	0.566
BRCA1	P38398-1.2	M1411W	Pathogenic	0.805
BRCA1	P38398-1.2	M1411Y	Pathogenic	0.72
BRCA1	P38398-1.2	A1412C	Neutral	0.399
BRCA1	P38398-1.2	A1412D	Pathogenic	0.604
BRCA1	P38398-1.2	A1412E	Pathogenic	0.613
BRCA1	P38398-1.2	A1412F	Pathogenic	0.801
BRCA1	P38398-1.2	A1412G	Neutral	0.401
BRCA1	P38398-1.2	A1412H	Pathogenic	0.739
BRCA1	P38398-1.2	A1412I	Pathogenic	0.687
BRCA1	P38398-1.2	A1412K	Pathogenic	0.737
BRCA1	P38398-1.2	A1412L	Pathogenic	0.687
BRCA1	P38398-1.2	A1412M	Pathogenic	0.689
BRCA1	P38398-1.2	A1412N	Pathogenic	0.631
BRCA1	P38398-1.2	A1412P	Pathogenic	0.512
BRCA1	P38398-1.2	A1412Q	Pathogenic	0.641
BRCA1	P38398-1.2	A1412R	Pathogenic	0.789
BRCA1	P38398-1.2	A1412S	Neutral	0.258
BRCA1	P38398-1.2	A1412T	Neutral	0.44
BRCA1	P38398-1.2	A1412V	Pathogenic	0.502
BRCA1	P38398-1.2	A1412W	Pathogenic	0.914
BRCA1	P38398-1.2	A1412Y	Pathogenic	0.824
BRCA1	P38398-1.2	E1413A	Neutral	0.017
BRCA1	P38398-1.2	E1413C	Neutral	0.033
BRCA1	P38398-1.2	E1413D	Neutral	0.004
BRCA1	P38398-1.2	E1413F	Neutral	0.024
BRCA1	P38398-1.2	E1413G	Neutral	0.038
BRCA1	P38398-1.2	E1413H	Neutral	0.006
BRCA1	P38398-1.2	E1413I	Neutral	0.019
BRCA1	P38398-1.2	E1413K	Neutral	0.006
BRCA1	P38398-1.2	E1413L	Neutral	0.019
BRCA1	P38398-1.2	E1413M	Neutral	0.014
BRCA1	P38398-1.2	E1413N	Neutral	0.007
BRCA1	P38398-1.2	E1413P	Neutral	0.01
BRCA1	P38398-1.2	E1413Q	Neutral	0.003
BRCA1	P38398-1.2	E1413R	Neutral	0.011
BRCA1	P38398-1.2	E1413S	Neutral	0.011
BRCA1	P38398-1.2	E1413T	Neutral	0.01
BRCA1	P38398-1.2	E1413V	Neutral	0.011
BRCA1	P38398-1.2	E1413W	Neutral	0.044
BRCA1	P38398-1.2	E1413Y	Neutral	0.02
BRCA1	P38398-1.2	L1414A	Pathogenic	0.656
BRCA1	P38398-1.2	L1414C	Pathogenic	0.559
BRCA1	P38398-1.2	L1414D	Pathogenic	0.765
BRCA1	P38398-1.2	L1414E	Pathogenic	0.604
BRCA1	P38398-1.2	L1414F	Neutral	0.328
BRCA1	P38398-1.2	L1414G	Pathogenic	0.896
BRCA1	P38398-1.2	L1414H	Pathogenic	0.559
BRCA1	P38398-1.2	L1414I	Neutral	0.156
BRCA1	P38398-1.2	L1414K	Neutral	0.49
BRCA1	P38398-1.2	L1414M	Neutral	0.155
BRCA1	P38398-1.2	L1414N	Pathogenic	0.671
BRCA1	P38398-1.2	L1414P	Pathogenic	0.705
BRCA1	P38398-1.2	L1414Q	Neutral	0.489
BRCA1	P38398-1.2	L1414R	Pathogenic	0.562
BRCA1	P38398-1.2	L1414S	Pathogenic	0.704
BRCA1	P38398-1.2	L1414T	Pathogenic	0.516
BRCA1	P38398-1.2	L1414V	Neutral	0.287
BRCA1	P38398-1.2	L1414W	Pathogenic	0.651
BRCA1	P38398-1.2	L1414Y	Neutral	0.442
BRCA1	P38398-1.2	E1415A	Pathogenic	0.665
BRCA1	P38398-1.2	E1415C	Pathogenic	0.793
BRCA1	P38398-1.2	E1415D	Neutral	0.284
BRCA1	P38398-1.2	E1415F	Pathogenic	0.737
BRCA1	P38398-1.2	E1415G	Pathogenic	0.814
BRCA1	P38398-1.2	E1415H	Neutral	0.4
BRCA1	P38398-1.2	E1415I	Pathogenic	0.687
BRCA1	P38398-1.2	E1415K	Neutral	0.405
BRCA1	P38398-1.2	E1415L	Pathogenic	0.688
BRCA1	P38398-1.2	E1415M	Pathogenic	0.607
BRCA1	P38398-1.2	E1415N	Neutral	0.425
BRCA1	P38398-1.2	E1415P	Pathogenic	0.542
BRCA1	P38398-1.2	E1415Q	Neutral	0.229
BRCA1	P38398-1.2	E1415R	Pathogenic	0.567
BRCA1	P38398-1.2	E1415S	Pathogenic	0.549
BRCA1	P38398-1.2	E1415T	Pathogenic	0.528
BRCA1	P38398-1.2	E1415V	Pathogenic	0.547
BRCA1	P38398-1.2	E1415W	Pathogenic	0.838
BRCA1	P38398-1.2	E1415Y	Pathogenic	0.694
BRCA1	P38398-1.2	A1416C	Pathogenic	0.647
BRCA1	P38398-1.2	A1416D	Pathogenic	0.808
BRCA1	P38398-1.2	A1416E	Pathogenic	0.814
BRCA1	P38398-1.2	A1416F	Pathogenic	0.917
BRCA1	P38398-1.2	A1416G	Pathogenic	0.649
BRCA1	P38398-1.2	A1416H	Pathogenic	0.887
BRCA1	P38398-1.2	A1416I	Pathogenic	0.858
BRCA1	P38398-1.2	A1416K	Pathogenic	0.886
BRCA1	P38398-1.2	A1416L	Pathogenic	0.858
BRCA1	P38398-1.2	A1416M	Pathogenic	0.859
BRCA1	P38398-1.2	A1416N	Pathogenic	0.825
BRCA1	P38398-1.2	A1416P	Pathogenic	0.744
BRCA1	P38398-1.2	A1416Q	Pathogenic	0.832
BRCA1	P38398-1.2	A1416R	Pathogenic	0.912
BRCA1	P38398-1.2	A1416S	Neutral	0.49
BRCA1	P38398-1.2	A1416T	Pathogenic	0.685
BRCA1	P38398-1.2	A1416V	Pathogenic	0.736
BRCA1	P38398-1.2	A1416W	Pathogenic	0.967
BRCA1	P38398-1.2	A1416Y	Pathogenic	0.928
BRCA1	P38398-1.2	V1417A	Pathogenic	0.724
BRCA1	P38398-1.2	V1417C	Pathogenic	0.714
BRCA1	P38398-1.2	V1417D	Pathogenic	0.818
BRCA1	P38398-1.2	V1417E	Pathogenic	0.714
BRCA1	P38398-1.2	V1417F	Pathogenic	0.76
BRCA1	P38398-1.2	V1417G	Pathogenic	0.922
BRCA1	P38398-1.2	V1417H	Pathogenic	0.817
BRCA1	P38398-1.2	V1417I	Neutral	0.367
BRCA1	P38398-1.2	V1417K	Pathogenic	0.816
BRCA1	P38398-1.2	V1417L	Pathogenic	0.546
BRCA1	P38398-1.2	V1417M	Pathogenic	0.548
BRCA1	P38398-1.2	V1417N	Pathogenic	0.801
BRCA1	P38398-1.2	V1417P	Pathogenic	0.766
BRCA1	P38398-1.2	V1417Q	Pathogenic	0.738
BRCA1	P38398-1.2	V1417R	Pathogenic	0.895
BRCA1	P38398-1.2	V1417S	Pathogenic	0.825
BRCA1	P38398-1.2	V1417T	Pathogenic	0.595
BRCA1	P38398-1.2	V1417W	Pathogenic	0.924
BRCA1	P38398-1.2	V1417Y	Pathogenic	0.785
BRCA1	P38398-1.2	L1418A	Pathogenic	0.819
BRCA1	P38398-1.2	L1418C	Pathogenic	0.751
BRCA1	P38398-1.2	L1418D	Pathogenic	0.886
BRCA1	P38398-1.2	L1418E	Pathogenic	0.784
BRCA1	P38398-1.2	L1418F	Pathogenic	0.538
BRCA1	P38398-1.2	L1418G	Pathogenic	0.953
BRCA1	P38398-1.2	L1418H	Pathogenic	0.751
BRCA1	P38398-1.2	L1418I	Neutral	0.305
BRCA1	P38398-1.2	L1418K	Pathogenic	0.696
BRCA1	P38398-1.2	L1418M	Neutral	0.304
BRCA1	P38398-1.2	L1418N	Pathogenic	0.829
BRCA1	P38398-1.2	L1418P	Pathogenic	0.85
BRCA1	P38398-1.2	L1418Q	Pathogenic	0.694
BRCA1	P38398-1.2	L1418R	Pathogenic	0.753
BRCA1	P38398-1.2	L1418S	Pathogenic	0.85
BRCA1	P38398-1.2	L1418T	Pathogenic	0.718
BRCA1	P38398-1.2	L1418V	Neutral	0.489
BRCA1	P38398-1.2	L1418W	Pathogenic	0.816
BRCA1	P38398-1.2	L1418Y	Pathogenic	0.654
BRCA1	P38398-1.2	E1419A	Pathogenic	0.649
BRCA1	P38398-1.2	E1419C	Pathogenic	0.781
BRCA1	P38398-1.2	E1419D	Neutral	0.27
BRCA1	P38398-1.2	E1419F	Pathogenic	0.723
BRCA1	P38398-1.2	E1419G	Pathogenic	0.803
BRCA1	P38398-1.2	E1419H	Neutral	0.382
BRCA1	P38398-1.2	E1419I	Pathogenic	0.671
BRCA1	P38398-1.2	E1419K	Neutral	0.387
BRCA1	P38398-1.2	E1419L	Pathogenic	0.672
BRCA1	P38398-1.2	E1419M	Pathogenic	0.589
BRCA1	P38398-1.2	E1419N	Neutral	0.407
BRCA1	P38398-1.2	E1419P	Pathogenic	0.524
BRCA1	P38398-1.2	E1419Q	Neutral	0.216
BRCA1	P38398-1.2	E1419R	Pathogenic	0.548
BRCA1	P38398-1.2	E1419S	Pathogenic	0.531
BRCA1	P38398-1.2	E1419T	Pathogenic	0.509
BRCA1	P38398-1.2	E1419V	Pathogenic	0.529
BRCA1	P38398-1.2	E1419W	Pathogenic	0.828
BRCA1	P38398-1.2	E1419Y	Pathogenic	0.678
BRCA1	P38398-1.2	Q1420A	Neutral	0.385
BRCA1	P38398-1.2	Q1420C	Neutral	0.456
BRCA1	P38398-1.2	Q1420D	Neutral	0.203
BRCA1	P38398-1.2	Q1420E	Neutral	0.076
BRCA1	P38398-1.2	Q1420F	Neutral	0.414
BRCA1	P38398-1.2	Q1420G	Pathogenic	0.58
BRCA1	P38398-1.2	Q1420H	Neutral	0.144
BRCA1	P38398-1.2	Q1420I	Neutral	0.356
BRCA1	P38398-1.2	Q1420K	Neutral	0.144
BRCA1	P38398-1.2	Q1420L	Neutral	0.278
BRCA1	P38398-1.2	Q1420M	Neutral	0.158
BRCA1	P38398-1.2	Q1420N	Neutral	0.186
BRCA1	P38398-1.2	Q1420P	Neutral	0.271
BRCA1	P38398-1.2	Q1420R	Neutral	0.184
BRCA1	P38398-1.2	Q1420S	Neutral	0.277
BRCA1	P38398-1.2	Q1420T	Neutral	0.26
BRCA1	P38398-1.2	Q1420V	Neutral	0.275
BRCA1	P38398-1.2	Q1420W	Neutral	0.475
BRCA1	P38398-1.2	Q1420Y	Neutral	0.284
BRCA1	P38398-1.2	H1421A	Neutral	0.399
BRCA1	P38398-1.2	H1421C	Neutral	0.382
BRCA1	P38398-1.2	H1421D	Neutral	0.211
BRCA1	P38398-1.2	H1421E	Neutral	0.111
BRCA1	P38398-1.2	H1421F	Neutral	0.174
BRCA1	P38398-1.2	H1421G	Pathogenic	0.504
BRCA1	P38398-1.2	H1421I	Neutral	0.255
BRCA1	P38398-1.2	H1421K	Neutral	0.176
BRCA1	P38398-1.2	H1421L	Neutral	0.255
BRCA1	P38398-1.2	H1421M	Neutral	0.194
BRCA1	P38398-1.2	H1421N	Neutral	0.104
BRCA1	P38398-1.2	H1421P	Neutral	0.283
BRCA1	P38398-1.2	H1421Q	Neutral	0.101
BRCA1	P38398-1.2	H1421R	Neutral	0.165
BRCA1	P38398-1.2	H1421S	Neutral	0.288
BRCA1	P38398-1.2	H1421T	Neutral	0.272
BRCA1	P38398-1.2	H1421V	Neutral	0.288
BRCA1	P38398-1.2	H1421W	Neutral	0.359
BRCA1	P38398-1.2	H1421Y	Neutral	0.076
BRCA1	P38398-1.2	G1422A	Neutral	0.196
BRCA1	P38398-1.2	G1422C	Pathogenic	0.522
BRCA1	P38398-1.2	G1422D	Neutral	0.372
BRCA1	P38398-1.2	G1422E	Pathogenic	0.561
BRCA1	P38398-1.2	G1422F	Pathogenic	0.762
BRCA1	P38398-1.2	G1422H	Pathogenic	0.611
BRCA1	P38398-1.2	G1422I	Pathogenic	0.783
BRCA1	P38398-1.2	G1422K	Pathogenic	0.693
BRCA1	P38398-1.2	G1422L	Pathogenic	0.783
BRCA1	P38398-1.2	G1422M	Pathogenic	0.717
BRCA1	P38398-1.2	G1422N	Neutral	0.316
BRCA1	P38398-1.2	G1422P	Neutral	0.455
BRCA1	P38398-1.2	G1422Q	Pathogenic	0.59
BRCA1	P38398-1.2	G1422R	Pathogenic	0.751
BRCA1	P38398-1.2	G1422S	Neutral	0.219
BRCA1	P38398-1.2	G1422T	Neutral	0.474
BRCA1	P38398-1.2	G1422V	Pathogenic	0.624
BRCA1	P38398-1.2	G1422W	Pathogenic	0.804
BRCA1	P38398-1.2	G1422Y	Pathogenic	0.788
BRCA1	P38398-1.2	S1423A	Neutral	0.138
BRCA1	P38398-1.2	S1423C	Neutral	0.277
BRCA1	P38398-1.2	S1423D	Neutral	0.23
BRCA1	P38398-1.2	S1423E	Neutral	0.309
BRCA1	P38398-1.2	S1423F	Pathogenic	0.617
BRCA1	P38398-1.2	S1423G	Neutral	0.261
BRCA1	P38398-1.2	S1423H	Neutral	0.442
BRCA1	P38398-1.2	S1423I	Pathogenic	0.557
BRCA1	P38398-1.2	S1423K	Neutral	0.441
BRCA1	P38398-1.2	S1423L	Pathogenic	0.558
BRCA1	P38398-1.2	S1423M	Neutral	0.469
BRCA1	P38398-1.2	S1423N	Neutral	0.189
BRCA1	P38398-1.2	S1423P	Neutral	0.296
BRCA1	P38398-1.2	S1423Q	Neutral	0.335
BRCA1	P38398-1.2	S1423R	Pathogenic	0.603
BRCA1	P38398-1.2	S1423T	Neutral	0.179
BRCA1	P38398-1.2	S1423V	Neutral	0.455
BRCA1	P38398-1.2	S1423W	Pathogenic	0.81
BRCA1	P38398-1.2	S1423Y	Pathogenic	0.651
BRCA1	P38398-1.2	Q1424A	Pathogenic	0.535
BRCA1	P38398-1.2	Q1424C	Pathogenic	0.607
BRCA1	P38398-1.2	Q1424D	Neutral	0.319
BRCA1	P38398-1.2	Q1424E	Neutral	0.132
BRCA1	P38398-1.2	Q1424F	Pathogenic	0.565
BRCA1	P38398-1.2	Q1424G	Pathogenic	0.718
BRCA1	P38398-1.2	Q1424H	Neutral	0.236
BRCA1	P38398-1.2	Q1424I	Pathogenic	0.505
BRCA1	P38398-1.2	Q1424K	Neutral	0.237
BRCA1	P38398-1.2	Q1424L	Neutral	0.415
BRCA1	P38398-1.2	Q1424M	Neutral	0.257
BRCA1	P38398-1.2	Q1424N	Neutral	0.297
BRCA1	P38398-1.2	Q1424P	Neutral	0.407
BRCA1	P38398-1.2	Q1424R	Neutral	0.293
BRCA1	P38398-1.2	Q1424S	Neutral	0.414
BRCA1	P38398-1.2	Q1424T	Neutral	0.393
BRCA1	P38398-1.2	Q1424V	Neutral	0.412
BRCA1	P38398-1.2	Q1424W	Pathogenic	0.625
BRCA1	P38398-1.2	Q1424Y	Neutral	0.422
BRCA1	P38398-1.2	P1425A	Neutral	0.018
BRCA1	P38398-1.2	P1425C	Neutral	0.025
BRCA1	P38398-1.2	P1425D	Neutral	0.011
BRCA1	P38398-1.2	P1425E	Neutral	0.016
BRCA1	P38398-1.2	P1425F	Neutral	0.081
BRCA1	P38398-1.2	P1425G	Neutral	0.039
BRCA1	P38398-1.2	P1425H	Neutral	0.029
BRCA1	P38398-1.2	P1425I	Neutral	0.046
BRCA1	P38398-1.2	P1425K	Neutral	0.029
BRCA1	P38398-1.2	P1425L	Neutral	0.046
BRCA1	P38398-1.2	P1425M	Neutral	0.033
BRCA1	P38398-1.2	P1425N	Neutral	0.018
BRCA1	P38398-1.2	P1425Q	Neutral	0.018
BRCA1	P38398-1.2	P1425R	Neutral	0.053
BRCA1	P38398-1.2	P1425S	Neutral	0.016
BRCA1	P38398-1.2	P1425T	Neutral	0.012
BRCA1	P38398-1.2	P1425V	Neutral	0.022
BRCA1	P38398-1.2	P1425W	Neutral	0.141
BRCA1	P38398-1.2	P1425Y	Neutral	0.067
BRCA1	P38398-1.2	S1426A	Neutral	0.075
BRCA1	P38398-1.2	S1426C	Neutral	0.163
BRCA1	P38398-1.2	S1426D	Neutral	0.132
BRCA1	P38398-1.2	S1426E	Neutral	0.185
BRCA1	P38398-1.2	S1426F	Neutral	0.45
BRCA1	P38398-1.2	S1426G	Neutral	0.153
BRCA1	P38398-1.2	S1426H	Neutral	0.287
BRCA1	P38398-1.2	S1426I	Neutral	0.391
BRCA1	P38398-1.2	S1426K	Neutral	0.287
BRCA1	P38398-1.2	S1426L	Neutral	0.391
BRCA1	P38398-1.2	S1426M	Neutral	0.311
BRCA1	P38398-1.2	S1426N	Neutral	0.106
BRCA1	P38398-1.2	S1426P	Neutral	0.176
BRCA1	P38398-1.2	S1426Q	Neutral	0.204
BRCA1	P38398-1.2	S1426R	Neutral	0.436
BRCA1	P38398-1.2	S1426T	Neutral	0.1
BRCA1	P38398-1.2	S1426V	Neutral	0.298
BRCA1	P38398-1.2	S1426W	Pathogenic	0.685
BRCA1	P38398-1.2	S1426Y	Neutral	0.487
BRCA1	P38398-1.2	N1427A	Neutral	0.008
BRCA1	P38398-1.2	N1427C	Neutral	0.007
BRCA1	P38398-1.2	N1427D	Neutral	0.002
BRCA1	P38398-1.2	N1427E	Neutral	0.003
BRCA1	P38398-1.2	N1427F	Neutral	0.013
BRCA1	P38398-1.2	N1427G	Neutral	0.006
BRCA1	P38398-1.2	N1427H	Neutral	0.002
BRCA1	P38398-1.2	N1427I	Neutral	0.01
BRCA1	P38398-1.2	N1427K	Neutral	0.005
BRCA1	P38398-1.2	N1427L	Neutral	0.01
BRCA1	P38398-1.2	N1427M	Neutral	0.007
BRCA1	P38398-1.2	N1427P	Neutral	0.005
BRCA1	P38398-1.2	N1427Q	Neutral	0.003
BRCA1	P38398-1.2	N1427R	Neutral	0.006
BRCA1	P38398-1.2	N1427S	Neutral	0.002
BRCA1	P38398-1.2	N1427T	Neutral	0.002
BRCA1	P38398-1.2	N1427V	Neutral	0.007
BRCA1	P38398-1.2	N1427W	Neutral	0.034
BRCA1	P38398-1.2	N1427Y	Neutral	0.011
BRCA1	P38398-1.2	S1428A	Neutral	0.002
BRCA1	P38398-1.2	S1428C	Neutral	0.004
BRCA1	P38398-1.2	S1428D	Neutral	0.003
BRCA1	P38398-1.2	S1428E	Neutral	0.004
BRCA1	P38398-1.2	S1428F	Neutral	0.016
BRCA1	P38398-1.2	S1428G	Neutral	0.004
BRCA1	P38398-1.2	S1428H	Neutral	0.008
BRCA1	P38398-1.2	S1428I	Neutral	0.013
BRCA1	P38398-1.2	S1428K	Neutral	0.008
BRCA1	P38398-1.2	S1428L	Neutral	0.013
BRCA1	P38398-1.2	S1428M	Neutral	0.009
BRCA1	P38398-1.2	S1428N	Neutral	0.002
BRCA1	P38398-1.2	S1428P	Neutral	0.004
BRCA1	P38398-1.2	S1428Q	Neutral	0.005
BRCA1	P38398-1.2	S1428R	Neutral	0.015
BRCA1	P38398-1.2	S1428T	Neutral	0.002
BRCA1	P38398-1.2	S1428V	Neutral	0.008
BRCA1	P38398-1.2	S1428W	Neutral	0.041
BRCA1	P38398-1.2	S1428Y	Neutral	0.018
BRCA1	P38398-1.2	Y1429A	Pathogenic	0.658
BRCA1	P38398-1.2	Y1429C	Pathogenic	0.561
BRCA1	P38398-1.2	Y1429D	Pathogenic	0.614
BRCA1	P38398-1.2	Y1429E	Neutral	0.427
BRCA1	P38398-1.2	Y1429F	Neutral	0.064
BRCA1	P38398-1.2	Y1429G	Pathogenic	0.808
BRCA1	P38398-1.2	Y1429H	Neutral	0.126
BRCA1	P38398-1.2	Y1429I	Neutral	0.273
BRCA1	P38398-1.2	Y1429K	Neutral	0.293
BRCA1	P38398-1.2	Y1429L	Neutral	0.274
BRCA1	P38398-1.2	Y1429M	Neutral	0.276
BRCA1	P38398-1.2	Y1429N	Neutral	0.499
BRCA1	P38398-1.2	Y1429P	Pathogenic	0.626
BRCA1	P38398-1.2	Y1429Q	Neutral	0.318
BRCA1	P38398-1.2	Y1429R	Neutral	0.298
BRCA1	P38398-1.2	Y1429S	Pathogenic	0.626
BRCA1	P38398-1.2	Y1429T	Pathogenic	0.519
BRCA1	P38398-1.2	Y1429V	Neutral	0.367
BRCA1	P38398-1.2	Y1429W	Neutral	0.123
BRCA1	P38398-1.2	P1430A	Neutral	0.024
BRCA1	P38398-1.2	P1430C	Neutral	0.032
BRCA1	P38398-1.2	P1430D	Neutral	0.014
BRCA1	P38398-1.2	P1430E	Neutral	0.021
BRCA1	P38398-1.2	P1430F	Neutral	0.104
BRCA1	P38398-1.2	P1430G	Neutral	0.05
BRCA1	P38398-1.2	P1430H	Neutral	0.037
BRCA1	P38398-1.2	P1430I	Neutral	0.059
BRCA1	P38398-1.2	P1430K	Neutral	0.037
BRCA1	P38398-1.2	P1430L	Neutral	0.06
BRCA1	P38398-1.2	P1430M	Neutral	0.043
BRCA1	P38398-1.2	P1430N	Neutral	0.023
BRCA1	P38398-1.2	P1430Q	Neutral	0.024
BRCA1	P38398-1.2	P1430R	Neutral	0.069
BRCA1	P38398-1.2	P1430S	Neutral	0.021
BRCA1	P38398-1.2	P1430T	Neutral	0.015
BRCA1	P38398-1.2	P1430V	Neutral	0.028
BRCA1	P38398-1.2	P1430W	Neutral	0.177
BRCA1	P38398-1.2	P1430Y	Neutral	0.086
BRCA1	P38398-1.2	S1431A	Neutral	0.092
BRCA1	P38398-1.2	S1431C	Neutral	0.195
BRCA1	P38398-1.2	S1431D	Neutral	0.159
BRCA1	P38398-1.2	S1431E	Neutral	0.22
BRCA1	P38398-1.2	S1431F	Pathogenic	0.505
BRCA1	P38398-1.2	S1431G	Neutral	0.183
BRCA1	P38398-1.2	S1431H	Neutral	0.334
BRCA1	P38398-1.2	S1431I	Neutral	0.444
BRCA1	P38398-1.2	S1431K	Neutral	0.333
BRCA1	P38398-1.2	S1431L	Neutral	0.444
BRCA1	P38398-1.2	S1431M	Neutral	0.359
BRCA1	P38398-1.2	S1431N	Neutral	0.128
BRCA1	P38398-1.2	S1431P	Neutral	0.21
BRCA1	P38398-1.2	S1431Q	Neutral	0.242
BRCA1	P38398-1.2	S1431R	Neutral	0.49
BRCA1	P38398-1.2	S1431T	Neutral	0.122
BRCA1	P38398-1.2	S1431V	Neutral	0.346
BRCA1	P38398-1.2	S1431W	Pathogenic	0.73
BRCA1	P38398-1.2	S1431Y	Pathogenic	0.542
BRCA1	P38398-1.2	I1432A	Neutral	0.028
BRCA1	P38398-1.2	I1432C	Neutral	0.019
BRCA1	P38398-1.2	I1432D	Neutral	0.033
BRCA1	P38398-1.2	I1432E	Neutral	0.022
BRCA1	P38398-1.2	I1432F	Neutral	0.007
BRCA1	P38398-1.2	I1432G	Neutral	0.114
BRCA1	P38398-1.2	I1432H	Neutral	0.019
BRCA1	P38398-1.2	I1432K	Neutral	0.02
BRCA1	P38398-1.2	I1432L	Neutral	0.003
BRCA1	P38398-1.2	I1432M	Neutral	0.004
BRCA1	P38398-1.2	I1432N	Neutral	0.03
BRCA1	P38398-1.2	I1432P	Neutral	0.034
BRCA1	P38398-1.2	I1432Q	Neutral	0.02
BRCA1	P38398-1.2	I1432R	Neutral	0.027
BRCA1	P38398-1.2	I1432S	Neutral	0.034
BRCA1	P38398-1.2	I1432T	Neutral	0.016
BRCA1	P38398-1.2	I1432V	Neutral	0.003
BRCA1	P38398-1.2	I1432W	Neutral	0.039
BRCA1	P38398-1.2	I1432Y	Neutral	0.012
BRCA1	P38398-1.2	I1433A	Neutral	0.028
BRCA1	P38398-1.2	I1433C	Neutral	0.019
BRCA1	P38398-1.2	I1433D	Neutral	0.033
BRCA1	P38398-1.2	I1433E	Neutral	0.023
BRCA1	P38398-1.2	I1433F	Neutral	0.007
BRCA1	P38398-1.2	I1433G	Neutral	0.115
BRCA1	P38398-1.2	I1433H	Neutral	0.019
BRCA1	P38398-1.2	I1433K	Neutral	0.021
BRCA1	P38398-1.2	I1433L	Neutral	0.003
BRCA1	P38398-1.2	I1433M	Neutral	0.004
BRCA1	P38398-1.2	I1433N	Neutral	0.03
BRCA1	P38398-1.2	I1433P	Neutral	0.035
BRCA1	P38398-1.2	I1433Q	Neutral	0.02
BRCA1	P38398-1.2	I1433R	Neutral	0.027
BRCA1	P38398-1.2	I1433S	Neutral	0.035
BRCA1	P38398-1.2	I1433T	Neutral	0.016
BRCA1	P38398-1.2	I1433V	Neutral	0.003
BRCA1	P38398-1.2	I1433W	Neutral	0.039
BRCA1	P38398-1.2	I1433Y	Neutral	0.012
BRCA1	P38398-1.2	S1434A	Neutral	0.001
BRCA1	P38398-1.2	S1434C	Neutral	0.003
BRCA1	P38398-1.2	S1434D	Neutral	0.002
BRCA1	P38398-1.2	S1434E	Neutral	0.004
BRCA1	P38398-1.2	S1434F	Neutral	0.013
BRCA1	P38398-1.2	S1434G	Neutral	0.003
BRCA1	P38398-1.2	S1434H	Neutral	0.006
BRCA1	P38398-1.2	S1434I	Neutral	0.01
BRCA1	P38398-1.2	S1434K	Neutral	0.006
BRCA1	P38398-1.2	S1434L	Neutral	0.01
BRCA1	P38398-1.2	S1434M	Neutral	0.007
BRCA1	P38398-1.2	S1434N	Neutral	0.002
BRCA1	P38398-1.2	S1434P	Neutral	0.003
BRCA1	P38398-1.2	S1434Q	Neutral	0.004
BRCA1	P38398-1.2	S1434R	Neutral	0.012
BRCA1	P38398-1.2	S1434T	Neutral	0.002
BRCA1	P38398-1.2	S1434V	Neutral	0.007
BRCA1	P38398-1.2	S1434W	Neutral	0.034
BRCA1	P38398-1.2	S1434Y	Neutral	0.015
BRCA1	P38398-1.2	D1435A	Neutral	0.282
BRCA1	P38398-1.2	D1435C	Neutral	0.268
BRCA1	P38398-1.2	D1435E	Neutral	0.075
BRCA1	P38398-1.2	D1435F	Neutral	0.461
BRCA1	P38398-1.2	D1435G	Neutral	0.295
BRCA1	P38398-1.2	D1435H	Neutral	0.226
BRCA1	P38398-1.2	D1435I	Neutral	0.401
BRCA1	P38398-1.2	D1435K	Neutral	0.302
BRCA1	P38398-1.2	D1435L	Neutral	0.492
BRCA1	P38398-1.2	D1435M	Neutral	0.404
BRCA1	P38398-1.2	D1435N	Neutral	0.081
BRCA1	P38398-1.2	D1435P	Neutral	0.14
BRCA1	P38398-1.2	D1435Q	Neutral	0.158
BRCA1	P38398-1.2	D1435R	Neutral	0.454
BRCA1	P38398-1.2	D1435S	Neutral	0.143
BRCA1	P38398-1.2	D1435T	Neutral	0.144
BRCA1	P38398-1.2	D1435V	Neutral	0.308
BRCA1	P38398-1.2	D1435W	Pathogenic	0.695
BRCA1	P38398-1.2	D1435Y	Neutral	0.499
BRCA1	P38398-1.2	S1436A	Neutral	0.016
BRCA1	P38398-1.2	S1436C	Neutral	0.038
BRCA1	P38398-1.2	S1436D	Neutral	0.03
BRCA1	P38398-1.2	S1436E	Neutral	0.044
BRCA1	P38398-1.2	S1436F	Neutral	0.142
BRCA1	P38398-1.2	S1436G	Neutral	0.035
BRCA1	P38398-1.2	S1436H	Neutral	0.075
BRCA1	P38398-1.2	S1436I	Neutral	0.115
BRCA1	P38398-1.2	S1436K	Neutral	0.075
BRCA1	P38398-1.2	S1436L	Neutral	0.115
BRCA1	P38398-1.2	S1436M	Neutral	0.083
BRCA1	P38398-1.2	S1436N	Neutral	0.023
BRCA1	P38398-1.2	S1436P	Neutral	0.041
BRCA1	P38398-1.2	S1436Q	Neutral	0.049
BRCA1	P38398-1.2	S1436R	Neutral	0.135
BRCA1	P38398-1.2	S1436T	Neutral	0.022
BRCA1	P38398-1.2	S1436V	Neutral	0.079
BRCA1	P38398-1.2	S1436W	Neutral	0.305
BRCA1	P38398-1.2	S1436Y	Neutral	0.161
BRCA1	P38398-1.2	S1437A	Neutral	0.009
BRCA1	P38398-1.2	S1437C	Neutral	0.022
BRCA1	P38398-1.2	S1437D	Neutral	0.017
BRCA1	P38398-1.2	S1437E	Neutral	0.025
BRCA1	P38398-1.2	S1437F	Neutral	0.086
BRCA1	P38398-1.2	S1437G	Neutral	0.02
BRCA1	P38398-1.2	S1437H	Neutral	0.044
BRCA1	P38398-1.2	S1437I	Neutral	0.068
BRCA1	P38398-1.2	S1437K	Neutral	0.044
BRCA1	P38398-1.2	S1437L	Neutral	0.068
BRCA1	P38398-1.2	S1437M	Neutral	0.049
BRCA1	P38398-1.2	S1437N	Neutral	0.013
BRCA1	P38398-1.2	S1437P	Neutral	0.024
BRCA1	P38398-1.2	S1437Q	Neutral	0.028
BRCA1	P38398-1.2	S1437R	Neutral	0.081
BRCA1	P38398-1.2	S1437T	Neutral	0.013
BRCA1	P38398-1.2	S1437V	Neutral	0.046
BRCA1	P38398-1.2	S1437W	Neutral	0.199
BRCA1	P38398-1.2	S1437Y	Neutral	0.098
BRCA1	P38398-1.2	A1438C	Neutral	0.012
BRCA1	P38398-1.2	A1438D	Neutral	0.028
BRCA1	P38398-1.2	A1438E	Neutral	0.029
BRCA1	P38398-1.2	A1438F	Neutral	0.069
BRCA1	P38398-1.2	A1438G	Neutral	0.012
BRCA1	P38398-1.2	A1438H	Neutral	0.05
BRCA1	P38398-1.2	A1438I	Neutral	0.039
BRCA1	P38398-1.2	A1438K	Neutral	0.049
BRCA1	P38398-1.2	A1438L	Neutral	0.039
BRCA1	P38398-1.2	A1438M	Neutral	0.039
BRCA1	P38398-1.2	A1438N	Neutral	0.031
BRCA1	P38398-1.2	A1438P	Neutral	0.019
BRCA1	P38398-1.2	A1438Q	Neutral	0.032
BRCA1	P38398-1.2	A1438R	Neutral	0.065
BRCA1	P38398-1.2	A1438S	Neutral	0.006
BRCA1	P38398-1.2	A1438T	Neutral	0.014
BRCA1	P38398-1.2	A1438V	Neutral	0.018
BRCA1	P38398-1.2	A1438W	Neutral	0.165
BRCA1	P38398-1.2	A1438Y	Neutral	0.08
BRCA1	P38398-1.2	L1439A	Neutral	0.008
BRCA1	P38398-1.2	L1439C	Neutral	0.005
BRCA1	P38398-1.2	L1439D	Neutral	0.014
BRCA1	P38398-1.2	L1439E	Neutral	0.006
BRCA1	P38398-1.2	L1439F	Neutral	0.002
BRCA1	P38398-1.2	L1439G	Neutral	0.035
BRCA1	P38398-1.2	L1439H	Neutral	0.005
BRCA1	P38398-1.2	L1439I	Neutral	0.001
BRCA1	P38398-1.2	L1439K	Neutral	0.004
BRCA1	P38398-1.2	L1439M	Neutral	0.001
BRCA1	P38398-1.2	L1439N	Neutral	0.009
BRCA1	P38398-1.2	L1439P	Neutral	0.01
BRCA1	P38398-1.2	L1439Q	Neutral	0.004
BRCA1	P38398-1.2	L1439R	Neutral	0.005
BRCA1	P38398-1.2	L1439S	Neutral	0.01
BRCA1	P38398-1.2	L1439T	Neutral	0.005
BRCA1	P38398-1.2	L1439V	Neutral	0.002
BRCA1	P38398-1.2	L1439W	Neutral	0.008
BRCA1	P38398-1.2	L1439Y	Neutral	0.003
BRCA1	P38398-1.2	E1440A	Neutral	0.161
BRCA1	P38398-1.2	E1440C	Neutral	0.27
BRCA1	P38398-1.2	E1440D	Neutral	0.037
BRCA1	P38398-1.2	E1440F	Neutral	0.213
BRCA1	P38398-1.2	E1440G	Neutral	0.297
BRCA1	P38398-1.2	E1440H	Neutral	0.06
BRCA1	P38398-1.2	E1440I	Neutral	0.175
BRCA1	P38398-1.2	E1440K	Neutral	0.062
BRCA1	P38398-1.2	E1440L	Neutral	0.175
BRCA1	P38398-1.2	E1440M	Neutral	0.13
BRCA1	P38398-1.2	E1440N	Neutral	0.066
BRCA1	P38398-1.2	E1440P	Neutral	0.102
BRCA1	P38398-1.2	E1440Q	Neutral	0.028
BRCA1	P38398-1.2	E1440R	Neutral	0.112
BRCA1	P38398-1.2	E1440S	Neutral	0.105
BRCA1	P38398-1.2	E1440T	Neutral	0.097
BRCA1	P38398-1.2	E1440V	Neutral	0.104
BRCA1	P38398-1.2	E1440W	Neutral	0.333
BRCA1	P38398-1.2	E1440Y	Neutral	0.179
BRCA1	P38398-1.2	D1441A	Neutral	0.18
BRCA1	P38398-1.2	D1441C	Neutral	0.17
BRCA1	P38398-1.2	D1441E	Neutral	0.044
BRCA1	P38398-1.2	D1441F	Neutral	0.324
BRCA1	P38398-1.2	D1441G	Neutral	0.19
BRCA1	P38398-1.2	D1441H	Neutral	0.141
BRCA1	P38398-1.2	D1441I	Neutral	0.273
BRCA1	P38398-1.2	D1441K	Neutral	0.195
BRCA1	P38398-1.2	D1441L	Neutral	0.351
BRCA1	P38398-1.2	D1441M	Neutral	0.275
BRCA1	P38398-1.2	D1441N	Neutral	0.047
BRCA1	P38398-1.2	D1441P	Neutral	0.083
BRCA1	P38398-1.2	D1441Q	Neutral	0.095
BRCA1	P38398-1.2	D1441R	Neutral	0.317
BRCA1	P38398-1.2	D1441S	Neutral	0.085
BRCA1	P38398-1.2	D1441T	Neutral	0.086
BRCA1	P38398-1.2	D1441V	Neutral	0.199
BRCA1	P38398-1.2	D1441W	Pathogenic	0.56
BRCA1	P38398-1.2	D1441Y	Neutral	0.357
BRCA1	P38398-1.2	L1442A	Neutral	0.164
BRCA1	P38398-1.2	L1442C	Neutral	0.115
BRCA1	P38398-1.2	L1442D	Neutral	0.251
BRCA1	P38398-1.2	L1442E	Neutral	0.135
BRCA1	P38398-1.2	L1442F	Neutral	0.048
BRCA1	P38398-1.2	L1442G	Neutral	0.469
BRCA1	P38398-1.2	L1442H	Neutral	0.115
BRCA1	P38398-1.2	L1442I	Neutral	0.019
BRCA1	P38398-1.2	L1442K	Neutral	0.09
BRCA1	P38398-1.2	L1442M	Neutral	0.019
BRCA1	P38398-1.2	L1442N	Neutral	0.173
BRCA1	P38398-1.2	L1442P	Neutral	0.197
BRCA1	P38398-1.2	L1442Q	Neutral	0.089
BRCA1	P38398-1.2	L1442R	Neutral	0.117
BRCA1	P38398-1.2	L1442S	Neutral	0.197
BRCA1	P38398-1.2	L1442T	Neutral	0.099
BRCA1	P38398-1.2	L1442V	Neutral	0.04
BRCA1	P38398-1.2	L1442W	Neutral	0.161
BRCA1	P38398-1.2	L1442Y	Neutral	0.075
BRCA1	P38398-1.2	R1443A	Neutral	0.007
BRCA1	P38398-1.2	R1443C	Neutral	0.009
BRCA1	P38398-1.2	R1443D	Neutral	0.006
BRCA1	P38398-1.2	R1443E	Neutral	0.002
BRCA1	P38398-1.2	R1443F	Neutral	0.003
BRCA1	P38398-1.2	R1443G	Neutral	0.015
BRCA1	P38398-1.2	R1443H	Neutral	0.002
BRCA1	P38398-1.2	R1443I	Neutral	0.004
BRCA1	P38398-1.2	R1443K	Neutral	0.001
BRCA1	P38398-1.2	R1443L	Neutral	0.003
BRCA1	P38398-1.2	R1443M	Neutral	0.002
BRCA1	P38398-1.2	R1443N	Neutral	0.003
BRCA1	P38398-1.2	R1443P	Neutral	0.006
BRCA1	P38398-1.2	R1443Q	Neutral	0.001
BRCA1	P38398-1.2	R1443S	Neutral	0.006
BRCA1	P38398-1.2	R1443T	Neutral	0.004
BRCA1	P38398-1.2	R1443V	Neutral	0.006
BRCA1	P38398-1.2	R1443W	Neutral	0.003
BRCA1	P38398-1.2	R1443Y	Neutral	0.002
BRCA1	P38398-1.2	N1444A	Neutral	0.032
BRCA1	P38398-1.2	N1444C	Neutral	0.03
BRCA1	P38398-1.2	N1444D	Neutral	0.007
BRCA1	P38398-1.2	N1444E	Neutral	0.011
BRCA1	P38398-1.2	N1444F	Neutral	0.054
BRCA1	P38398-1.2	N1444G	Neutral	0.024
BRCA1	P38398-1.2	N1444H	Neutral	0.009
BRCA1	P38398-1.2	N1444I	Neutral	0.043
BRCA1	P38398-1.2	N1444K	Neutral	0.02
BRCA1	P38398-1.2	N1444L	Neutral	0.043
BRCA1	P38398-1.2	N1444M	Neutral	0.031
BRCA1	P38398-1.2	N1444P	Neutral	0.019
BRCA1	P38398-1.2	N1444Q	Neutral	0.012
BRCA1	P38398-1.2	N1444R	Neutral	0.026
BRCA1	P38398-1.2	N1444S	Neutral	0.01
BRCA1	P38398-1.2	N1444T	Neutral	0.009
BRCA1	P38398-1.2	N1444V	Neutral	0.029
BRCA1	P38398-1.2	N1444W	Neutral	0.132
BRCA1	P38398-1.2	N1444Y	Neutral	0.044
BRCA1	P38398-1.2	P1445A	Neutral	0.08
BRCA1	P38398-1.2	P1445C	Neutral	0.105
BRCA1	P38398-1.2	P1445D	Neutral	0.049
BRCA1	P38398-1.2	P1445E	Neutral	0.072
BRCA1	P38398-1.2	P1445F	Neutral	0.293
BRCA1	P38398-1.2	P1445G	Neutral	0.159
BRCA1	P38398-1.2	P1445H	Neutral	0.122
BRCA1	P38398-1.2	P1445I	Neutral	0.184
BRCA1	P38398-1.2	P1445K	Neutral	0.121
BRCA1	P38398-1.2	P1445L	Neutral	0.184
BRCA1	P38398-1.2	P1445M	Neutral	0.137
BRCA1	P38398-1.2	P1445N	Neutral	0.077
BRCA1	P38398-1.2	P1445Q	Neutral	0.08
BRCA1	P38398-1.2	P1445R	Neutral	0.209
BRCA1	P38398-1.2	P1445S	Neutral	0.07
BRCA1	P38398-1.2	P1445T	Neutral	0.052
BRCA1	P38398-1.2	P1445V	Neutral	0.094
BRCA1	P38398-1.2	P1445W	Neutral	0.433
BRCA1	P38398-1.2	P1445Y	Neutral	0.251
BRCA1	P38398-1.2	E1446A	Neutral	0.037
BRCA1	P38398-1.2	E1446C	Neutral	0.07
BRCA1	P38398-1.2	E1446D	Neutral	0.008
BRCA1	P38398-1.2	E1446F	Neutral	0.052
BRCA1	P38398-1.2	E1446G	Neutral	0.079
BRCA1	P38398-1.2	E1446H	Neutral	0.013
BRCA1	P38398-1.2	E1446I	Neutral	0.041
BRCA1	P38398-1.2	E1446K	Neutral	0.013
BRCA1	P38398-1.2	E1446L	Neutral	0.041
BRCA1	P38398-1.2	E1446M	Neutral	0.029
BRCA1	P38398-1.2	E1446N	Neutral	0.014
BRCA1	P38398-1.2	E1446P	Neutral	0.023
BRCA1	P38398-1.2	E1446Q	Neutral	0.006
BRCA1	P38398-1.2	E1446R	Neutral	0.025
BRCA1	P38398-1.2	E1446S	Neutral	0.023
BRCA1	P38398-1.2	E1446T	Neutral	0.021
BRCA1	P38398-1.2	E1446V	Neutral	0.023
BRCA1	P38398-1.2	E1446W	Neutral	0.092
BRCA1	P38398-1.2	E1446Y	Neutral	0.042
BRCA1	P38398-1.2	Q1447A	Neutral	0.186
BRCA1	P38398-1.2	Q1447C	Neutral	0.235
BRCA1	P38398-1.2	Q1447D	Neutral	0.085
BRCA1	P38398-1.2	Q1447E	Neutral	0.029
BRCA1	P38398-1.2	Q1447F	Neutral	0.206
BRCA1	P38398-1.2	Q1447G	Neutral	0.336
BRCA1	P38398-1.2	Q1447H	Neutral	0.058
BRCA1	P38398-1.2	Q1447I	Neutral	0.169
BRCA1	P38398-1.2	Q1447K	Neutral	0.058
BRCA1	P38398-1.2	Q1447L	Neutral	0.124
BRCA1	P38398-1.2	Q1447M	Neutral	0.064
BRCA1	P38398-1.2	Q1447N	Neutral	0.077
BRCA1	P38398-1.2	Q1447P	Neutral	0.12
BRCA1	P38398-1.2	Q1447R	Neutral	0.076
BRCA1	P38398-1.2	Q1447S	Neutral	0.123
BRCA1	P38398-1.2	Q1447T	Neutral	0.114
BRCA1	P38398-1.2	Q1447V	Neutral	0.122
BRCA1	P38398-1.2	Q1447W	Neutral	0.249
BRCA1	P38398-1.2	Q1447Y	Neutral	0.127
BRCA1	P38398-1.2	S1448A	Neutral	0.001
BRCA1	P38398-1.2	S1448C	Neutral	0.001
BRCA1	P38398-1.2	S1448D	Neutral	0.001
BRCA1	P38398-1.2	S1448E	Neutral	0.002
BRCA1	P38398-1.2	S1448F	Neutral	0.005
BRCA1	P38398-1.2	S1448G	Neutral	0.001
BRCA1	P38398-1.2	S1448H	Neutral	0.003
BRCA1	P38398-1.2	S1448I	Neutral	0.004
BRCA1	P38398-1.2	S1448K	Neutral	0.003
BRCA1	P38398-1.2	S1448L	Neutral	0.004
BRCA1	P38398-1.2	S1448M	Neutral	0.003
BRCA1	P38398-1.2	S1448N	Neutral	0.001
BRCA1	P38398-1.2	S1448P	Neutral	0.001
BRCA1	P38398-1.2	S1448Q	Neutral	0.002
BRCA1	P38398-1.2	S1448R	Neutral	0.005
BRCA1	P38398-1.2	S1448T	Neutral	0.001
BRCA1	P38398-1.2	S1448V	Neutral	0.003
BRCA1	P38398-1.2	S1448W	Neutral	0.014
BRCA1	P38398-1.2	S1448Y	Neutral	0.006
BRCA1	P38398-1.2	T1449A	Neutral	0.012
BRCA1	P38398-1.2	T1449C	Neutral	0.012
BRCA1	P38398-1.2	T1449D	Neutral	0.01
BRCA1	P38398-1.2	T1449E	Neutral	0.014
BRCA1	P38398-1.2	T1449F	Neutral	0.035
BRCA1	P38398-1.2	T1449G	Neutral	0.038
BRCA1	P38398-1.2	T1449H	Neutral	0.025
BRCA1	P38398-1.2	T1449I	Neutral	0.019
BRCA1	P38398-1.2	T1449K	Neutral	0.025
BRCA1	P38398-1.2	T1449L	Neutral	0.019
BRCA1	P38398-1.2	T1449M	Neutral	0.019
BRCA1	P38398-1.2	T1449N	Neutral	0.007
BRCA1	P38398-1.2	T1449P	Neutral	0.011
BRCA1	P38398-1.2	T1449Q	Neutral	0.016
BRCA1	P38398-1.2	T1449R	Neutral	0.033
BRCA1	P38398-1.2	T1449S	Neutral	0.008
BRCA1	P38398-1.2	T1449V	Neutral	0.009
BRCA1	P38398-1.2	T1449W	Neutral	0.062
BRCA1	P38398-1.2	T1449Y	Neutral	0.04
BRCA1	P38398-1.2	S1450A	Neutral	0.012
BRCA1	P38398-1.2	S1450C	Neutral	0.028
BRCA1	P38398-1.2	S1450D	Neutral	0.022
BRCA1	P38398-1.2	S1450E	Neutral	0.033
BRCA1	P38398-1.2	S1450F	Neutral	0.11
BRCA1	P38398-1.2	S1450G	Neutral	0.026
BRCA1	P38398-1.2	S1450H	Neutral	0.057
BRCA1	P38398-1.2	S1450I	Neutral	0.088
BRCA1	P38398-1.2	S1450K	Neutral	0.057
BRCA1	P38398-1.2	S1450L	Neutral	0.088
BRCA1	P38398-1.2	S1450M	Neutral	0.063
BRCA1	P38398-1.2	S1450N	Neutral	0.017
BRCA1	P38398-1.2	S1450P	Neutral	0.031
BRCA1	P38398-1.2	S1450Q	Neutral	0.037
BRCA1	P38398-1.2	S1450R	Neutral	0.104
BRCA1	P38398-1.2	S1450T	Neutral	0.016
BRCA1	P38398-1.2	S1450V	Neutral	0.06
BRCA1	P38398-1.2	S1450W	Neutral	0.247
BRCA1	P38398-1.2	S1450Y	Neutral	0.125
BRCA1	P38398-1.2	E1451A	Neutral	0.029
BRCA1	P38398-1.2	E1451C	Neutral	0.054
BRCA1	P38398-1.2	E1451D	Neutral	0.006
BRCA1	P38398-1.2	E1451F	Neutral	0.04
BRCA1	P38398-1.2	E1451G	Neutral	0.061
BRCA1	P38398-1.2	E1451H	Neutral	0.01
BRCA1	P38398-1.2	E1451I	Neutral	0.031
BRCA1	P38398-1.2	E1451K	Neutral	0.01
BRCA1	P38398-1.2	E1451L	Neutral	0.032
BRCA1	P38398-1.2	E1451M	Neutral	0.022
BRCA1	P38398-1.2	E1451N	Neutral	0.011
BRCA1	P38398-1.2	E1451P	Neutral	0.017
BRCA1	P38398-1.2	E1451Q	Neutral	0.004
BRCA1	P38398-1.2	E1451R	Neutral	0.019
BRCA1	P38398-1.2	E1451S	Neutral	0.018
BRCA1	P38398-1.2	E1451T	Neutral	0.016
BRCA1	P38398-1.2	E1451V	Neutral	0.018
BRCA1	P38398-1.2	E1451W	Neutral	0.071
BRCA1	P38398-1.2	E1451Y	Neutral	0.032
BRCA1	P38398-1.2	K1452A	Pathogenic	0.964
BRCA1	P38398-1.2	K1452C	Pathogenic	0.973
BRCA1	P38398-1.2	K1452D	Pathogenic	0.941
BRCA1	P38398-1.2	K1452E	Pathogenic	0.837
BRCA1	P38398-1.2	K1452F	Pathogenic	0.922
BRCA1	P38398-1.2	K1452G	Pathogenic	0.983
BRCA1	P38398-1.2	K1452H	Pathogenic	0.896
BRCA1	P38398-1.2	K1452I	Pathogenic	0.938
BRCA1	P38398-1.2	K1452L	Pathogenic	0.913
BRCA1	P38398-1.2	K1452M	Pathogenic	0.881
BRCA1	P38398-1.2	K1452N	Pathogenic	0.908
BRCA1	P38398-1.2	K1452P	Pathogenic	0.941
BRCA1	P38398-1.2	K1452Q	Pathogenic	0.82
BRCA1	P38398-1.2	K1452R	Pathogenic	0.73
BRCA1	P38398-1.2	K1452S	Pathogenic	0.942
BRCA1	P38398-1.2	K1452T	Pathogenic	0.937
BRCA1	P38398-1.2	K1452V	Pathogenic	0.942
BRCA1	P38398-1.2	K1452W	Pathogenic	0.956
BRCA1	P38398-1.2	K1452Y	Pathogenic	0.905
BRCA1	P38398-1.2	A1453C	Neutral	0.479
BRCA1	P38398-1.2	A1453D	Pathogenic	0.678
BRCA1	P38398-1.2	A1453E	Pathogenic	0.687
BRCA1	P38398-1.2	A1453F	Pathogenic	0.848
BRCA1	P38398-1.2	A1453G	Neutral	0.481
BRCA1	P38398-1.2	A1453H	Pathogenic	0.796
BRCA1	P38398-1.2	A1453I	Pathogenic	0.752
BRCA1	P38398-1.2	A1453K	Pathogenic	0.795
BRCA1	P38398-1.2	A1453L	Pathogenic	0.752
BRCA1	P38398-1.2	A1453M	Pathogenic	0.754
BRCA1	P38398-1.2	A1453N	Pathogenic	0.703
BRCA1	P38398-1.2	A1453P	Pathogenic	0.592
BRCA1	P38398-1.2	A1453Q	Pathogenic	0.712
BRCA1	P38398-1.2	A1453R	Pathogenic	0.838
BRCA1	P38398-1.2	A1453S	Neutral	0.325
BRCA1	P38398-1.2	A1453T	Pathogenic	0.521
BRCA1	P38398-1.2	A1453V	Pathogenic	0.582
BRCA1	P38398-1.2	A1453W	Pathogenic	0.937
BRCA1	P38398-1.2	A1453Y	Pathogenic	0.866
BRCA1	P38398-1.2	V1454A	Neutral	0.031
BRCA1	P38398-1.2	V1454C	Neutral	0.03
BRCA1	P38398-1.2	V1454D	Neutral	0.053
BRCA1	P38398-1.2	V1454E	Neutral	0.03
BRCA1	P38398-1.2	V1454F	Neutral	0.038
BRCA1	P38398-1.2	V1454G	Neutral	0.128
BRCA1	P38398-1.2	V1454H	Neutral	0.052
BRCA1	P38398-1.2	V1454I	Neutral	0.007
BRCA1	P38398-1.2	V1454K	Neutral	0.052
BRCA1	P38398-1.2	V1454L	Neutral	0.015
BRCA1	P38398-1.2	V1454M	Neutral	0.015
BRCA1	P38398-1.2	V1454N	Neutral	0.048
BRCA1	P38398-1.2	V1454P	Neutral	0.039
BRCA1	P38398-1.2	V1454Q	Neutral	0.034
BRCA1	P38398-1.2	V1454R	Neutral	0.095
BRCA1	P38398-1.2	V1454S	Neutral	0.055
BRCA1	P38398-1.2	V1454T	Neutral	0.018
BRCA1	P38398-1.2	V1454W	Neutral	0.131
BRCA1	P38398-1.2	V1454Y	Neutral	0.043
BRCA1	P38398-1.2	L1455A	Neutral	0.45
BRCA1	P38398-1.2	L1455C	Neutral	0.352
BRCA1	P38398-1.2	L1455D	Pathogenic	0.584
BRCA1	P38398-1.2	L1455E	Neutral	0.396
BRCA1	P38398-1.2	L1455F	Neutral	0.173
BRCA1	P38398-1.2	L1455G	Pathogenic	0.787
BRCA1	P38398-1.2	L1455H	Neutral	0.352
BRCA1	P38398-1.2	L1455I	Neutral	0.074
BRCA1	P38398-1.2	L1455K	Neutral	0.292
BRCA1	P38398-1.2	L1455M	Neutral	0.073
BRCA1	P38398-1.2	L1455N	Neutral	0.466
BRCA1	P38398-1.2	L1455P	Pathogenic	0.506
BRCA1	P38398-1.2	L1455Q	Neutral	0.291
BRCA1	P38398-1.2	L1455R	Neutral	0.355
BRCA1	P38398-1.2	L1455S	Pathogenic	0.506
BRCA1	P38398-1.2	L1455T	Neutral	0.314
BRCA1	P38398-1.2	L1455V	Neutral	0.147
BRCA1	P38398-1.2	L1455W	Neutral	0.445
BRCA1	P38398-1.2	L1455Y	Neutral	0.254
BRCA1	P38398-1.2	T1456A	Neutral	0.351
BRCA1	P38398-1.2	T1456C	Neutral	0.335
BRCA1	P38398-1.2	T1456D	Neutral	0.309
BRCA1	P38398-1.2	T1456E	Neutral	0.38
BRCA1	P38398-1.2	T1456F	Pathogenic	0.608
BRCA1	P38398-1.2	T1456G	Pathogenic	0.63
BRCA1	P38398-1.2	T1456H	Pathogenic	0.522
BRCA1	P38398-1.2	T1456I	Neutral	0.458
BRCA1	P38398-1.2	T1456K	Pathogenic	0.52
BRCA1	P38398-1.2	T1456L	Neutral	0.458
BRCA1	P38398-1.2	T1456M	Neutral	0.461
BRCA1	P38398-1.2	T1456N	Neutral	0.242
BRCA1	P38398-1.2	T1456P	Neutral	0.317
BRCA1	P38398-1.2	T1456Q	Neutral	0.408
BRCA1	P38398-1.2	T1456R	Pathogenic	0.591
BRCA1	P38398-1.2	T1456S	Neutral	0.247
BRCA1	P38398-1.2	T1456V	Neutral	0.28
BRCA1	P38398-1.2	T1456W	Pathogenic	0.741
BRCA1	P38398-1.2	T1456Y	Pathogenic	0.643
BRCA1	P38398-1.2	S1457A	Neutral	0.08
BRCA1	P38398-1.2	S1457C	Neutral	0.172
BRCA1	P38398-1.2	S1457D	Neutral	0.14
BRCA1	P38398-1.2	S1457E	Neutral	0.195
BRCA1	P38398-1.2	S1457F	Neutral	0.467
BRCA1	P38398-1.2	S1457G	Neutral	0.161
BRCA1	P38398-1.2	S1457H	Neutral	0.301
BRCA1	P38398-1.2	S1457I	Neutral	0.407
BRCA1	P38398-1.2	S1457K	Neutral	0.301
BRCA1	P38398-1.2	S1457L	Neutral	0.407
BRCA1	P38398-1.2	S1457M	Neutral	0.325
BRCA1	P38398-1.2	S1457N	Neutral	0.112
BRCA1	P38398-1.2	S1457P	Neutral	0.186
BRCA1	P38398-1.2	S1457Q	Neutral	0.215
BRCA1	P38398-1.2	S1457R	Neutral	0.452
BRCA1	P38398-1.2	S1457T	Neutral	0.106
BRCA1	P38398-1.2	S1457V	Neutral	0.312
BRCA1	P38398-1.2	S1457W	Pathogenic	0.699
BRCA1	P38398-1.2	S1457Y	Pathogenic	0.504
BRCA1	P38398-1.2	Q1458A	Neutral	0.047
BRCA1	P38398-1.2	Q1458C	Neutral	0.062
BRCA1	P38398-1.2	Q1458D	Neutral	0.02
BRCA1	P38398-1.2	Q1458E	Neutral	0.006
BRCA1	P38398-1.2	Q1458F	Neutral	0.053
BRCA1	P38398-1.2	Q1458G	Neutral	0.098
BRCA1	P38398-1.2	Q1458H	Neutral	0.013
BRCA1	P38398-1.2	Q1458I	Neutral	0.042
BRCA1	P38398-1.2	Q1458K	Neutral	0.013
BRCA1	P38398-1.2	Q1458L	Neutral	0.029
BRCA1	P38398-1.2	Q1458M	Neutral	0.015
BRCA1	P38398-1.2	Q1458N	Neutral	0.018
BRCA1	P38398-1.2	Q1458P	Neutral	0.028
BRCA1	P38398-1.2	Q1458R	Neutral	0.017
BRCA1	P38398-1.2	Q1458S	Neutral	0.029
BRCA1	P38398-1.2	Q1458T	Neutral	0.027
BRCA1	P38398-1.2	Q1458V	Neutral	0.029
BRCA1	P38398-1.2	Q1458W	Neutral	0.066
BRCA1	P38398-1.2	Q1458Y	Neutral	0.03
BRCA1	P38398-1.2	K1459A	Neutral	0.067
BRCA1	P38398-1.2	K1459C	Neutral	0.088
BRCA1	P38398-1.2	K1459D	Neutral	0.041
BRCA1	P38398-1.2	K1459E	Neutral	0.014
BRCA1	P38398-1.2	K1459F	Neutral	0.031
BRCA1	P38398-1.2	K1459G	Neutral	0.137
BRCA1	P38398-1.2	K1459H	Neutral	0.023
BRCA1	P38398-1.2	K1459I	Neutral	0.039
BRCA1	P38398-1.2	K1459L	Neutral	0.028
BRCA1	P38398-1.2	K1459M	Neutral	0.019
BRCA1	P38398-1.2	K1459N	Neutral	0.026
BRCA1	P38398-1.2	K1459P	Neutral	0.041
BRCA1	P38398-1.2	K1459Q	Neutral	0.012
BRCA1	P38398-1.2	K1459R	Neutral	0.007
BRCA1	P38398-1.2	K1459S	Neutral	0.042
BRCA1	P38398-1.2	K1459T	Neutral	0.039
BRCA1	P38398-1.2	K1459V	Neutral	0.042
BRCA1	P38398-1.2	K1459W	Neutral	0.056
BRCA1	P38398-1.2	K1459Y	Neutral	0.025
BRCA1	P38398-1.2	S1460A	Neutral	0.016
BRCA1	P38398-1.2	S1460C	Neutral	0.038
BRCA1	P38398-1.2	S1460D	Neutral	0.03
BRCA1	P38398-1.2	S1460E	Neutral	0.044
BRCA1	P38398-1.2	S1460F	Neutral	0.141
BRCA1	P38398-1.2	S1460G	Neutral	0.035
BRCA1	P38398-1.2	S1460H	Neutral	0.075
BRCA1	P38398-1.2	S1460I	Neutral	0.114
BRCA1	P38398-1.2	S1460K	Neutral	0.075
BRCA1	P38398-1.2	S1460L	Neutral	0.114
BRCA1	P38398-1.2	S1460M	Neutral	0.083
BRCA1	P38398-1.2	S1460N	Neutral	0.023
BRCA1	P38398-1.2	S1460P	Neutral	0.041
BRCA1	P38398-1.2	S1460Q	Neutral	0.049
BRCA1	P38398-1.2	S1460R	Neutral	0.134
BRCA1	P38398-1.2	S1460T	Neutral	0.022
BRCA1	P38398-1.2	S1460V	Neutral	0.078
BRCA1	P38398-1.2	S1460W	Neutral	0.304
BRCA1	P38398-1.2	S1460Y	Neutral	0.16
BRCA1	P38398-1.2	S1461A	Neutral	0.002
BRCA1	P38398-1.2	S1461C	Neutral	0.005
BRCA1	P38398-1.2	S1461D	Neutral	0.004
BRCA1	P38398-1.2	S1461E	Neutral	0.006
BRCA1	P38398-1.2	S1461F	Neutral	0.022
BRCA1	P38398-1.2	S1461G	Neutral	0.005
BRCA1	P38398-1.2	S1461H	Neutral	0.011
BRCA1	P38398-1.2	S1461I	Neutral	0.017
BRCA1	P38398-1.2	S1461K	Neutral	0.011
BRCA1	P38398-1.2	S1461L	Neutral	0.017
BRCA1	P38398-1.2	S1461M	Neutral	0.012
BRCA1	P38398-1.2	S1461N	Neutral	0.003
BRCA1	P38398-1.2	S1461P	Neutral	0.006
BRCA1	P38398-1.2	S1461Q	Neutral	0.007
BRCA1	P38398-1.2	S1461R	Neutral	0.02
BRCA1	P38398-1.2	S1461T	Neutral	0.003
BRCA1	P38398-1.2	S1461V	Neutral	0.011
BRCA1	P38398-1.2	S1461W	Neutral	0.056
BRCA1	P38398-1.2	S1461Y	Neutral	0.025
BRCA1	P38398-1.2	E1462A	Neutral	0.046
BRCA1	P38398-1.2	E1462C	Neutral	0.085
BRCA1	P38398-1.2	E1462D	Neutral	0.009
BRCA1	P38398-1.2	E1462F	Neutral	0.063
BRCA1	P38398-1.2	E1462G	Neutral	0.096
BRCA1	P38398-1.2	E1462H	Neutral	0.016
BRCA1	P38398-1.2	E1462I	Neutral	0.05
BRCA1	P38398-1.2	E1462K	Neutral	0.016
BRCA1	P38398-1.2	E1462L	Neutral	0.05
BRCA1	P38398-1.2	E1462M	Neutral	0.036
BRCA1	P38398-1.2	E1462N	Neutral	0.017
BRCA1	P38398-1.2	E1462P	Neutral	0.028
BRCA1	P38398-1.2	E1462Q	Neutral	0.007
BRCA1	P38398-1.2	E1462R	Neutral	0.031
BRCA1	P38398-1.2	E1462S	Neutral	0.029
BRCA1	P38398-1.2	E1462T	Neutral	0.026
BRCA1	P38398-1.2	E1462V	Neutral	0.028
BRCA1	P38398-1.2	E1462W	Neutral	0.111
BRCA1	P38398-1.2	E1462Y	Neutral	0.052
BRCA1	P38398-1.2	Y1463A	Neutral	0.419
BRCA1	P38398-1.2	Y1463C	Neutral	0.324
BRCA1	P38398-1.2	Y1463D	Neutral	0.374
BRCA1	P38398-1.2	Y1463E	Neutral	0.218
BRCA1	P38398-1.2	Y1463F	Neutral	0.025
BRCA1	P38398-1.2	Y1463G	Pathogenic	0.611
BRCA1	P38398-1.2	Y1463H	Neutral	0.051
BRCA1	P38398-1.2	Y1463I	Neutral	0.123
BRCA1	P38398-1.2	Y1463K	Neutral	0.134
BRCA1	P38398-1.2	Y1463L	Neutral	0.124
BRCA1	P38398-1.2	Y1463M	Neutral	0.125
BRCA1	P38398-1.2	Y1463N	Neutral	0.271
BRCA1	P38398-1.2	Y1463P	Neutral	0.386
BRCA1	P38398-1.2	Y1463Q	Neutral	0.149
BRCA1	P38398-1.2	Y1463R	Neutral	0.137
BRCA1	P38398-1.2	Y1463S	Neutral	0.385
BRCA1	P38398-1.2	Y1463T	Neutral	0.288
BRCA1	P38398-1.2	Y1463V	Neutral	0.178
BRCA1	P38398-1.2	Y1463W	Neutral	0.05
BRCA1	P38398-1.2	P1464A	Neutral	0.178
BRCA1	P38398-1.2	P1464C	Neutral	0.227
BRCA1	P38398-1.2	P1464D	Neutral	0.115
BRCA1	P38398-1.2	P1464E	Neutral	0.163
BRCA1	P38398-1.2	P1464F	Pathogenic	0.509
BRCA1	P38398-1.2	P1464G	Neutral	0.32
BRCA1	P38398-1.2	P1464H	Neutral	0.257
BRCA1	P38398-1.2	P1464I	Neutral	0.361
BRCA1	P38398-1.2	P1464K	Neutral	0.256
BRCA1	P38398-1.2	P1464L	Neutral	0.361
BRCA1	P38398-1.2	P1464M	Neutral	0.284
BRCA1	P38398-1.2	P1464N	Neutral	0.173
BRCA1	P38398-1.2	P1464Q	Neutral	0.179
BRCA1	P38398-1.2	P1464R	Neutral	0.397
BRCA1	P38398-1.2	P1464S	Neutral	0.158
BRCA1	P38398-1.2	P1464T	Neutral	0.122
BRCA1	P38398-1.2	P1464V	Neutral	0.206
BRCA1	P38398-1.2	P1464W	Pathogenic	0.657
BRCA1	P38398-1.2	P1464Y	Neutral	0.455
BRCA1	P38398-1.2	I1465A	Neutral	0.041
BRCA1	P38398-1.2	I1465C	Neutral	0.028
BRCA1	P38398-1.2	I1465D	Neutral	0.048
BRCA1	P38398-1.2	I1465E	Neutral	0.033
BRCA1	P38398-1.2	I1465F	Neutral	0.011
BRCA1	P38398-1.2	I1465G	Neutral	0.162
BRCA1	P38398-1.2	I1465H	Neutral	0.028
BRCA1	P38398-1.2	I1465K	Neutral	0.03
BRCA1	P38398-1.2	I1465L	Neutral	0.004
BRCA1	P38398-1.2	I1465M	Neutral	0.006
BRCA1	P38398-1.2	I1465N	Neutral	0.044
BRCA1	P38398-1.2	I1465P	Neutral	0.051
BRCA1	P38398-1.2	I1465Q	Neutral	0.03
BRCA1	P38398-1.2	I1465R	Neutral	0.04
BRCA1	P38398-1.2	I1465S	Neutral	0.051
BRCA1	P38398-1.2	I1465T	Neutral	0.023
BRCA1	P38398-1.2	I1465V	Neutral	0.004
BRCA1	P38398-1.2	I1465W	Neutral	0.057
BRCA1	P38398-1.2	I1465Y	Neutral	0.017
BRCA1	P38398-1.2	S1466A	Neutral	0.028
BRCA1	P38398-1.2	S1466C	Neutral	0.065
BRCA1	P38398-1.2	S1466D	Neutral	0.052
BRCA1	P38398-1.2	S1466E	Neutral	0.075
BRCA1	P38398-1.2	S1466F	Neutral	0.227
BRCA1	P38398-1.2	S1466G	Neutral	0.061
BRCA1	P38398-1.2	S1466H	Neutral	0.126
BRCA1	P38398-1.2	S1466I	Neutral	0.187
BRCA1	P38398-1.2	S1466K	Neutral	0.126
BRCA1	P38398-1.2	S1466L	Neutral	0.187
BRCA1	P38398-1.2	S1466M	Neutral	0.139
BRCA1	P38398-1.2	S1466N	Neutral	0.041
BRCA1	P38398-1.2	S1466P	Neutral	0.071
BRCA1	P38398-1.2	S1466Q	Neutral	0.084
BRCA1	P38398-1.2	S1466R	Neutral	0.217
BRCA1	P38398-1.2	S1466T	Neutral	0.038
BRCA1	P38398-1.2	S1466V	Neutral	0.132
BRCA1	P38398-1.2	S1466W	Neutral	0.439
BRCA1	P38398-1.2	S1466Y	Neutral	0.254
BRCA1	P38398-1.2	Q1467A	Neutral	0.133
BRCA1	P38398-1.2	Q1467C	Neutral	0.171
BRCA1	P38398-1.2	Q1467D	Neutral	0.059
BRCA1	P38398-1.2	Q1467E	Neutral	0.02
BRCA1	P38398-1.2	Q1467F	Neutral	0.148
BRCA1	P38398-1.2	Q1467G	Neutral	0.253
BRCA1	P38398-1.2	Q1467H	Neutral	0.04
BRCA1	P38398-1.2	Q1467I	Neutral	0.12
BRCA1	P38398-1.2	Q1467K	Neutral	0.04
BRCA1	P38398-1.2	Q1467L	Neutral	0.086
BRCA1	P38398-1.2	Q1467M	Neutral	0.044
BRCA1	P38398-1.2	Q1467N	Neutral	0.053
BRCA1	P38398-1.2	Q1467P	Neutral	0.084
BRCA1	P38398-1.2	Q1467R	Neutral	0.052
BRCA1	P38398-1.2	Q1467S	Neutral	0.086
BRCA1	P38398-1.2	Q1467T	Neutral	0.079
BRCA1	P38398-1.2	Q1467V	Neutral	0.085
BRCA1	P38398-1.2	Q1467W	Neutral	0.182
BRCA1	P38398-1.2	Q1467Y	Neutral	0.089
BRCA1	P38398-1.2	N1468A	Neutral	0.163
BRCA1	P38398-1.2	N1468C	Neutral	0.154
BRCA1	P38398-1.2	N1468D	Neutral	0.038
BRCA1	P38398-1.2	N1468E	Neutral	0.063
BRCA1	P38398-1.2	N1468F	Neutral	0.254
BRCA1	P38398-1.2	N1468G	Neutral	0.126
BRCA1	P38398-1.2	N1468H	Neutral	0.053
BRCA1	P38398-1.2	N1468I	Neutral	0.211
BRCA1	P38398-1.2	N1468K	Neutral	0.106
BRCA1	P38398-1.2	N1468L	Neutral	0.211
BRCA1	P38398-1.2	N1468M	Neutral	0.158
BRCA1	P38398-1.2	N1468P	Neutral	0.104
BRCA1	P38398-1.2	N1468Q	Neutral	0.069
BRCA1	P38398-1.2	N1468R	Neutral	0.137
BRCA1	P38398-1.2	N1468S	Neutral	0.055
BRCA1	P38398-1.2	N1468T	Neutral	0.05
BRCA1	P38398-1.2	N1468V	Neutral	0.151
BRCA1	P38398-1.2	N1468W	Neutral	0.476
BRCA1	P38398-1.2	N1468Y	Neutral	0.216
BRCA1	P38398-1.2	P1469A	Neutral	0.112
BRCA1	P38398-1.2	P1469C	Neutral	0.147
BRCA1	P38398-1.2	P1469D	Neutral	0.071
BRCA1	P38398-1.2	P1469E	Neutral	0.102
BRCA1	P38398-1.2	P1469F	Neutral	0.378
BRCA1	P38398-1.2	P1469G	Neutral	0.216
BRCA1	P38398-1.2	P1469H	Neutral	0.169
BRCA1	P38398-1.2	P1469I	Neutral	0.248
BRCA1	P38398-1.2	P1469K	Neutral	0.168
BRCA1	P38398-1.2	P1469L	Neutral	0.249
BRCA1	P38398-1.2	P1469M	Neutral	0.188
BRCA1	P38398-1.2	P1469N	Neutral	0.109
BRCA1	P38398-1.2	P1469Q	Neutral	0.114
BRCA1	P38398-1.2	P1469R	Neutral	0.279
BRCA1	P38398-1.2	P1469S	Neutral	0.099
BRCA1	P38398-1.2	P1469T	Neutral	0.075
BRCA1	P38398-1.2	P1469V	Neutral	0.132
BRCA1	P38398-1.2	P1469W	Pathogenic	0.529
BRCA1	P38398-1.2	P1469Y	Neutral	0.329
BRCA1	P38398-1.2	E1470A	Neutral	0.014
BRCA1	P38398-1.2	E1470C	Neutral	0.027
BRCA1	P38398-1.2	E1470D	Neutral	0.003
BRCA1	P38398-1.2	E1470F	Neutral	0.02
BRCA1	P38398-1.2	E1470G	Neutral	0.031
BRCA1	P38398-1.2	E1470H	Neutral	0.005
BRCA1	P38398-1.2	E1470I	Neutral	0.016
BRCA1	P38398-1.2	E1470K	Neutral	0.005
BRCA1	P38398-1.2	E1470L	Neutral	0.016
BRCA1	P38398-1.2	E1470M	Neutral	0.011
BRCA1	P38398-1.2	E1470N	Neutral	0.005
BRCA1	P38398-1.2	E1470P	Neutral	0.009
BRCA1	P38398-1.2	E1470Q	Neutral	0.002
BRCA1	P38398-1.2	E1470R	Neutral	0.01
BRCA1	P38398-1.2	E1470S	Neutral	0.009
BRCA1	P38398-1.2	E1470T	Neutral	0.008
BRCA1	P38398-1.2	E1470V	Neutral	0.009
BRCA1	P38398-1.2	E1470W	Neutral	0.037
BRCA1	P38398-1.2	E1470Y	Neutral	0.016
BRCA1	P38398-1.2	G1471A	Neutral	0.003
BRCA1	P38398-1.2	G1471C	Neutral	0.013
BRCA1	P38398-1.2	G1471D	Neutral	0.007
BRCA1	P38398-1.2	G1471E	Neutral	0.015
BRCA1	P38398-1.2	G1471F	Neutral	0.036
BRCA1	P38398-1.2	G1471H	Neutral	0.018
BRCA1	P38398-1.2	G1471I	Neutral	0.041
BRCA1	P38398-1.2	G1471K	Neutral	0.026
BRCA1	P38398-1.2	G1471L	Neutral	0.041
BRCA1	P38398-1.2	G1471M	Neutral	0.029
BRCA1	P38398-1.2	G1471N	Neutral	0.005
BRCA1	P38398-1.2	G1471P	Neutral	0.01
BRCA1	P38398-1.2	G1471Q	Neutral	0.017
BRCA1	P38398-1.2	G1471R	Neutral	0.034
BRCA1	P38398-1.2	G1471S	Neutral	0.003
BRCA1	P38398-1.2	G1471T	Neutral	0.011
BRCA1	P38398-1.2	G1471V	Neutral	0.019
BRCA1	P38398-1.2	G1471W	Neutral	0.046
BRCA1	P38398-1.2	G1471Y	Neutral	0.042
BRCA1	P38398-1.2	L1472A	Neutral	0.09
BRCA1	P38398-1.2	L1472C	Neutral	0.062
BRCA1	P38398-1.2	L1472D	Neutral	0.145
BRCA1	P38398-1.2	L1472E	Neutral	0.073
BRCA1	P38398-1.2	L1472F	Neutral	0.025
BRCA1	P38398-1.2	L1472G	Neutral	0.309
BRCA1	P38398-1.2	L1472H	Neutral	0.062
BRCA1	P38398-1.2	L1472I	Neutral	0.01
BRCA1	P38398-1.2	L1472K	Neutral	0.048
BRCA1	P38398-1.2	L1472M	Neutral	0.009
BRCA1	P38398-1.2	L1472N	Neutral	0.096
BRCA1	P38398-1.2	L1472P	Neutral	0.11
BRCA1	P38398-1.2	L1472Q	Neutral	0.047
BRCA1	P38398-1.2	L1472R	Neutral	0.063
BRCA1	P38398-1.2	L1472S	Neutral	0.11
BRCA1	P38398-1.2	L1472T	Neutral	0.053
BRCA1	P38398-1.2	L1472V	Neutral	0.02
BRCA1	P38398-1.2	L1472W	Neutral	0.089
BRCA1	P38398-1.2	L1472Y	Neutral	0.04
BRCA1	P38398-1.2	S1473A	Neutral	0.096
BRCA1	P38398-1.2	S1473C	Neutral	0.202
BRCA1	P38398-1.2	S1473D	Neutral	0.165
BRCA1	P38398-1.2	S1473E	Neutral	0.228
BRCA1	P38398-1.2	S1473F	Pathogenic	0.516
BRCA1	P38398-1.2	S1473G	Neutral	0.19
BRCA1	P38398-1.2	S1473H	Neutral	0.344
BRCA1	P38398-1.2	S1473I	Neutral	0.455
BRCA1	P38398-1.2	S1473K	Neutral	0.343
BRCA1	P38398-1.2	S1473L	Neutral	0.455
BRCA1	P38398-1.2	S1473M	Neutral	0.369
BRCA1	P38398-1.2	S1473N	Neutral	0.133
BRCA1	P38398-1.2	S1473P	Neutral	0.217
BRCA1	P38398-1.2	S1473Q	Neutral	0.25
BRCA1	P38398-1.2	S1473R	Pathogenic	0.501
BRCA1	P38398-1.2	S1473T	Neutral	0.126
BRCA1	P38398-1.2	S1473V	Neutral	0.356
BRCA1	P38398-1.2	S1473W	Pathogenic	0.739
BRCA1	P38398-1.2	S1473Y	Pathogenic	0.553
BRCA1	P38398-1.2	A1474C	Neutral	0.064
BRCA1	P38398-1.2	A1474D	Neutral	0.135
BRCA1	P38398-1.2	A1474E	Neutral	0.14
BRCA1	P38398-1.2	A1474F	Neutral	0.291
BRCA1	P38398-1.2	A1474G	Neutral	0.064
BRCA1	P38398-1.2	A1474H	Neutral	0.224
BRCA1	P38398-1.2	A1474I	Neutral	0.183
BRCA1	P38398-1.2	A1474K	Neutral	0.223
BRCA1	P38398-1.2	A1474L	Neutral	0.183
BRCA1	P38398-1.2	A1474M	Neutral	0.185
BRCA1	P38398-1.2	A1474N	Neutral	0.149
BRCA1	P38398-1.2	A1474P	Neutral	0.097
BRCA1	P38398-1.2	A1474Q	Neutral	0.154
BRCA1	P38398-1.2	A1474R	Neutral	0.277
BRCA1	P38398-1.2	A1474S	Neutral	0.034
BRCA1	P38398-1.2	A1474T	Neutral	0.074
BRCA1	P38398-1.2	A1474V	Neutral	0.094
BRCA1	P38398-1.2	A1474W	Pathogenic	0.522
BRCA1	P38398-1.2	A1474Y	Neutral	0.323
BRCA1	P38398-1.2	D1475A	Neutral	0.421
BRCA1	P38398-1.2	D1475C	Neutral	0.404
BRCA1	P38398-1.2	D1475E	Neutral	0.131
BRCA1	P38398-1.2	D1475F	Pathogenic	0.613
BRCA1	P38398-1.2	D1475G	Neutral	0.437
BRCA1	P38398-1.2	D1475H	Neutral	0.352
BRCA1	P38398-1.2	D1475I	Pathogenic	0.554
BRCA1	P38398-1.2	D1475K	Neutral	0.445
BRCA1	P38398-1.2	D1475L	Pathogenic	0.642
BRCA1	P38398-1.2	D1475M	Pathogenic	0.557
BRCA1	P38398-1.2	D1475N	Neutral	0.14
BRCA1	P38398-1.2	D1475P	Neutral	0.231
BRCA1	P38398-1.2	D1475Q	Neutral	0.258
BRCA1	P38398-1.2	D1475R	Pathogenic	0.606
BRCA1	P38398-1.2	D1475S	Neutral	0.236
BRCA1	P38398-1.2	D1475T	Neutral	0.237
BRCA1	P38398-1.2	D1475V	Neutral	0.452
BRCA1	P38398-1.2	D1475W	Pathogenic	0.808
BRCA1	P38398-1.2	D1475Y	Pathogenic	0.648
BRCA1	P38398-1.2	K1476A	Pathogenic	0.702
BRCA1	P38398-1.2	K1476C	Pathogenic	0.759
BRCA1	P38398-1.2	K1476D	Pathogenic	0.585
BRCA1	P38398-1.2	K1476E	Neutral	0.313
BRCA1	P38398-1.2	K1476F	Pathogenic	0.511
BRCA1	P38398-1.2	K1476G	Pathogenic	0.839
BRCA1	P38398-1.2	K1476H	Neutral	0.432
BRCA1	P38398-1.2	K1476I	Pathogenic	0.572
BRCA1	P38398-1.2	K1476L	Neutral	0.482
BRCA1	P38398-1.2	K1476M	Neutral	0.395
BRCA1	P38398-1.2	K1476N	Neutral	0.466
BRCA1	P38398-1.2	K1476P	Pathogenic	0.583
BRCA1	P38398-1.2	K1476Q	Neutral	0.288
BRCA1	P38398-1.2	K1476R	Neutral	0.193
BRCA1	P38398-1.2	K1476S	Pathogenic	0.59
BRCA1	P38398-1.2	K1476T	Pathogenic	0.569
BRCA1	P38398-1.2	K1476V	Pathogenic	0.589
BRCA1	P38398-1.2	K1476W	Pathogenic	0.659
BRCA1	P38398-1.2	K1476Y	Neutral	0.458
BRCA1	P38398-1.2	F1477A	Neutral	0.178
BRCA1	P38398-1.2	F1477C	Neutral	0.126
BRCA1	P38398-1.2	F1477D	Neutral	0.152
BRCA1	P38398-1.2	F1477E	Neutral	0.108
BRCA1	P38398-1.2	F1477G	Neutral	0.321
BRCA1	P38398-1.2	F1477H	Neutral	0.046
BRCA1	P38398-1.2	F1477I	Neutral	0.029
BRCA1	P38398-1.2	F1477K	Neutral	0.063
BRCA1	P38398-1.2	F1477L	Neutral	0.029
BRCA1	P38398-1.2	F1477M	Neutral	0.029
BRCA1	P38398-1.2	F1477N	Neutral	0.139
BRCA1	P38398-1.2	F1477P	Neutral	0.213
BRCA1	P38398-1.2	F1477Q	Neutral	0.098
BRCA1	P38398-1.2	F1477R	Neutral	0.082
BRCA1	P38398-1.2	F1477S	Neutral	0.159
BRCA1	P38398-1.2	F1477T	Neutral	0.108
BRCA1	P38398-1.2	F1477V	Neutral	0.062
BRCA1	P38398-1.2	F1477W	Neutral	0.03
BRCA1	P38398-1.2	F1477Y	Neutral	0.009
BRCA1	P38398-1.2	E1478A	Neutral	0.016
BRCA1	P38398-1.2	E1478C	Neutral	0.03
BRCA1	P38398-1.2	E1478D	Neutral	0.003
BRCA1	P38398-1.2	E1478F	Neutral	0.022
BRCA1	P38398-1.2	E1478G	Neutral	0.034
BRCA1	P38398-1.2	E1478H	Neutral	0.005
BRCA1	P38398-1.2	E1478I	Neutral	0.017
BRCA1	P38398-1.2	E1478K	Neutral	0.005
BRCA1	P38398-1.2	E1478L	Neutral	0.017
BRCA1	P38398-1.2	E1478M	Neutral	0.012
BRCA1	P38398-1.2	E1478N	Neutral	0.006
BRCA1	P38398-1.2	E1478P	Neutral	0.009
BRCA1	P38398-1.2	E1478Q	Neutral	0.002
BRCA1	P38398-1.2	E1478R	Neutral	0.01
BRCA1	P38398-1.2	E1478S	Neutral	0.01
BRCA1	P38398-1.2	E1478T	Neutral	0.009
BRCA1	P38398-1.2	E1478V	Neutral	0.01
BRCA1	P38398-1.2	E1478W	Neutral	0.04
BRCA1	P38398-1.2	E1478Y	Neutral	0.018
BRCA1	P38398-1.2	V1479A	Neutral	0.006
BRCA1	P38398-1.2	V1479C	Neutral	0.005
BRCA1	P38398-1.2	V1479D	Neutral	0.009
BRCA1	P38398-1.2	V1479E	Neutral	0.005
BRCA1	P38398-1.2	V1479F	Neutral	0.007
BRCA1	P38398-1.2	V1479G	Neutral	0.024
BRCA1	P38398-1.2	V1479H	Neutral	0.009
BRCA1	P38398-1.2	V1479I	Neutral	0.001
BRCA1	P38398-1.2	V1479K	Neutral	0.009
BRCA1	P38398-1.2	V1479L	Neutral	0.003
BRCA1	P38398-1.2	V1479M	Neutral	0.003
BRCA1	P38398-1.2	V1479N	Neutral	0.008
BRCA1	P38398-1.2	V1479P	Neutral	0.007
BRCA1	P38398-1.2	V1479Q	Neutral	0.006
BRCA1	P38398-1.2	V1479R	Neutral	0.018
BRCA1	P38398-1.2	V1479S	Neutral	0.01
BRCA1	P38398-1.2	V1479T	Neutral	0.003
BRCA1	P38398-1.2	V1479W	Neutral	0.025
BRCA1	P38398-1.2	V1479Y	Neutral	0.008
BRCA1	P38398-1.2	S1480A	Neutral	0.049
BRCA1	P38398-1.2	S1480C	Neutral	0.109
BRCA1	P38398-1.2	S1480D	Neutral	0.087
BRCA1	P38398-1.2	S1480E	Neutral	0.125
BRCA1	P38398-1.2	S1480F	Neutral	0.34
BRCA1	P38398-1.2	S1480G	Neutral	0.102
BRCA1	P38398-1.2	S1480H	Neutral	0.202
BRCA1	P38398-1.2	S1480I	Neutral	0.288
BRCA1	P38398-1.2	S1480K	Neutral	0.202
BRCA1	P38398-1.2	S1480L	Neutral	0.288
BRCA1	P38398-1.2	S1480M	Neutral	0.221
BRCA1	P38398-1.2	S1480N	Neutral	0.069
BRCA1	P38398-1.2	S1480P	Neutral	0.119
BRCA1	P38398-1.2	S1480Q	Neutral	0.139
BRCA1	P38398-1.2	S1480R	Neutral	0.327
BRCA1	P38398-1.2	S1480T	Neutral	0.066
BRCA1	P38398-1.2	S1480V	Neutral	0.211
BRCA1	P38398-1.2	S1480W	Pathogenic	0.578
BRCA1	P38398-1.2	S1480Y	Neutral	0.375
BRCA1	P38398-1.2	A1481C	Neutral	0.009
BRCA1	P38398-1.2	A1481D	Neutral	0.02
BRCA1	P38398-1.2	A1481E	Neutral	0.021
BRCA1	P38398-1.2	A1481F	Neutral	0.051
BRCA1	P38398-1.2	A1481G	Neutral	0.009
BRCA1	P38398-1.2	A1481H	Neutral	0.036
BRCA1	P38398-1.2	A1481I	Neutral	0.028
BRCA1	P38398-1.2	A1481K	Neutral	0.036
BRCA1	P38398-1.2	A1481L	Neutral	0.028
BRCA1	P38398-1.2	A1481M	Neutral	0.029
BRCA1	P38398-1.2	A1481N	Neutral	0.022
BRCA1	P38398-1.2	A1481P	Neutral	0.014
BRCA1	P38398-1.2	A1481Q	Neutral	0.023
BRCA1	P38398-1.2	A1481R	Neutral	0.047
BRCA1	P38398-1.2	A1481S	Neutral	0.005
BRCA1	P38398-1.2	A1481T	Neutral	0.01
BRCA1	P38398-1.2	A1481V	Neutral	0.013
BRCA1	P38398-1.2	A1481W	Neutral	0.125
BRCA1	P38398-1.2	A1481Y	Neutral	0.059
BRCA1	P38398-1.2	D1482A	Neutral	0.149
BRCA1	P38398-1.2	D1482C	Neutral	0.14
BRCA1	P38398-1.2	D1482E	Neutral	0.035
BRCA1	P38398-1.2	D1482F	Neutral	0.276
BRCA1	P38398-1.2	D1482G	Neutral	0.157
BRCA1	P38398-1.2	D1482H	Neutral	0.115
BRCA1	P38398-1.2	D1482I	Neutral	0.23
BRCA1	P38398-1.2	D1482K	Neutral	0.162
BRCA1	P38398-1.2	D1482L	Neutral	0.301
BRCA1	P38398-1.2	D1482M	Neutral	0.232
BRCA1	P38398-1.2	D1482N	Neutral	0.038
BRCA1	P38398-1.2	D1482P	Neutral	0.068
BRCA1	P38398-1.2	D1482Q	Neutral	0.077
BRCA1	P38398-1.2	D1482R	Neutral	0.27
BRCA1	P38398-1.2	D1482S	Neutral	0.069
BRCA1	P38398-1.2	D1482T	Neutral	0.07
BRCA1	P38398-1.2	D1482V	Neutral	0.166
BRCA1	P38398-1.2	D1482W	Pathogenic	0.504
BRCA1	P38398-1.2	D1482Y	Neutral	0.307
BRCA1	P38398-1.2	S1483A	Neutral	0.004
BRCA1	P38398-1.2	S1483C	Neutral	0.01
BRCA1	P38398-1.2	S1483D	Neutral	0.008
BRCA1	P38398-1.2	S1483E	Neutral	0.012
BRCA1	P38398-1.2	S1483F	Neutral	0.041
BRCA1	P38398-1.2	S1483G	Neutral	0.009
BRCA1	P38398-1.2	S1483H	Neutral	0.021
BRCA1	P38398-1.2	S1483I	Neutral	0.033
BRCA1	P38398-1.2	S1483K	Neutral	0.021
BRCA1	P38398-1.2	S1483L	Neutral	0.033
BRCA1	P38398-1.2	S1483M	Neutral	0.023
BRCA1	P38398-1.2	S1483N	Neutral	0.006
BRCA1	P38398-1.2	S1483P	Neutral	0.011
BRCA1	P38398-1.2	S1483Q	Neutral	0.013
BRCA1	P38398-1.2	S1483R	Neutral	0.039
BRCA1	P38398-1.2	S1483T	Neutral	0.006
BRCA1	P38398-1.2	S1483V	Neutral	0.022
BRCA1	P38398-1.2	S1483W	Neutral	0.103
BRCA1	P38398-1.2	S1483Y	Neutral	0.048
BRCA1	P38398-1.2	S1484A	Neutral	0.012
BRCA1	P38398-1.2	S1484C	Neutral	0.029
BRCA1	P38398-1.2	S1484D	Neutral	0.023
BRCA1	P38398-1.2	S1484E	Neutral	0.034
BRCA1	P38398-1.2	S1484F	Neutral	0.112
BRCA1	P38398-1.2	S1484G	Neutral	0.027
BRCA1	P38398-1.2	S1484H	Neutral	0.058
BRCA1	P38398-1.2	S1484I	Neutral	0.09
BRCA1	P38398-1.2	S1484K	Neutral	0.058
BRCA1	P38398-1.2	S1484L	Neutral	0.09
BRCA1	P38398-1.2	S1484M	Neutral	0.065
BRCA1	P38398-1.2	S1484N	Neutral	0.018
BRCA1	P38398-1.2	S1484P	Neutral	0.032
BRCA1	P38398-1.2	S1484Q	Neutral	0.038
BRCA1	P38398-1.2	S1484R	Neutral	0.106
BRCA1	P38398-1.2	S1484T	Neutral	0.017
BRCA1	P38398-1.2	S1484V	Neutral	0.062
BRCA1	P38398-1.2	S1484W	Neutral	0.251
BRCA1	P38398-1.2	S1484Y	Neutral	0.128
BRCA1	P38398-1.2	T1485A	Neutral	0.06
BRCA1	P38398-1.2	T1485C	Neutral	0.056
BRCA1	P38398-1.2	T1485D	Neutral	0.05
BRCA1	P38398-1.2	T1485E	Neutral	0.068
BRCA1	P38398-1.2	T1485F	Neutral	0.155
BRCA1	P38398-1.2	T1485G	Neutral	0.168
BRCA1	P38398-1.2	T1485H	Neutral	0.115
BRCA1	P38398-1.2	T1485I	Neutral	0.091
BRCA1	P38398-1.2	T1485K	Neutral	0.114
BRCA1	P38398-1.2	T1485L	Neutral	0.091
BRCA1	P38398-1.2	T1485M	Neutral	0.092
BRCA1	P38398-1.2	T1485N	Neutral	0.036
BRCA1	P38398-1.2	T1485P	Neutral	0.052
BRCA1	P38398-1.2	T1485Q	Neutral	0.076
BRCA1	P38398-1.2	T1485R	Neutral	0.146
BRCA1	P38398-1.2	T1485S	Neutral	0.037
BRCA1	P38398-1.2	T1485V	Neutral	0.044
BRCA1	P38398-1.2	T1485W	Neutral	0.254
BRCA1	P38398-1.2	T1485Y	Neutral	0.176
BRCA1	P38398-1.2	S1486A	Neutral	0.018
BRCA1	P38398-1.2	S1486C	Neutral	0.041
BRCA1	P38398-1.2	S1486D	Neutral	0.032
BRCA1	P38398-1.2	S1486E	Neutral	0.047
BRCA1	P38398-1.2	S1486F	Neutral	0.152
BRCA1	P38398-1.2	S1486G	Neutral	0.038
BRCA1	P38398-1.2	S1486H	Neutral	0.081
BRCA1	P38398-1.2	S1486I	Neutral	0.123
BRCA1	P38398-1.2	S1486K	Neutral	0.081
BRCA1	P38398-1.2	S1486L	Neutral	0.123
BRCA1	P38398-1.2	S1486M	Neutral	0.09
BRCA1	P38398-1.2	S1486N	Neutral	0.025
BRCA1	P38398-1.2	S1486P	Neutral	0.045
BRCA1	P38398-1.2	S1486Q	Neutral	0.053
BRCA1	P38398-1.2	S1486R	Neutral	0.145
BRCA1	P38398-1.2	S1486T	Neutral	0.024
BRCA1	P38398-1.2	S1486V	Neutral	0.085
BRCA1	P38398-1.2	S1486W	Neutral	0.323
BRCA1	P38398-1.2	S1486Y	Neutral	0.172
BRCA1	P38398-1.2	K1487A	Neutral	0.208
BRCA1	P38398-1.2	K1487C	Neutral	0.26
BRCA1	P38398-1.2	K1487D	Neutral	0.136
BRCA1	P38398-1.2	K1487E	Neutral	0.048
BRCA1	P38398-1.2	K1487F	Neutral	0.104
BRCA1	P38398-1.2	K1487G	Neutral	0.366
BRCA1	P38398-1.2	K1487H	Neutral	0.078
BRCA1	P38398-1.2	K1487I	Neutral	0.129
BRCA1	P38398-1.2	K1487L	Neutral	0.094
BRCA1	P38398-1.2	K1487M	Neutral	0.068
BRCA1	P38398-1.2	K1487N	Neutral	0.089
BRCA1	P38398-1.2	K1487P	Neutral	0.135
BRCA1	P38398-1.2	K1487Q	Neutral	0.043
BRCA1	P38398-1.2	K1487R	Neutral	0.026
BRCA1	P38398-1.2	K1487S	Neutral	0.138
BRCA1	P38398-1.2	K1487T	Neutral	0.128
BRCA1	P38398-1.2	K1487V	Neutral	0.137
BRCA1	P38398-1.2	K1487W	Neutral	0.177
BRCA1	P38398-1.2	K1487Y	Neutral	0.086
BRCA1	P38398-1.2	N1488A	Neutral	0.321
BRCA1	P38398-1.2	N1488C	Neutral	0.306
BRCA1	P38398-1.2	N1488D	Neutral	0.086
BRCA1	P38398-1.2	N1488E	Neutral	0.14
BRCA1	P38398-1.2	N1488F	Neutral	0.453
BRCA1	P38398-1.2	N1488G	Neutral	0.26
BRCA1	P38398-1.2	N1488H	Neutral	0.12
BRCA1	P38398-1.2	N1488I	Neutral	0.393
BRCA1	P38398-1.2	N1488K	Neutral	0.224
BRCA1	P38398-1.2	N1488L	Neutral	0.393
BRCA1	P38398-1.2	N1488M	Neutral	0.313
BRCA1	P38398-1.2	N1488P	Neutral	0.22
BRCA1	P38398-1.2	N1488Q	Neutral	0.153
BRCA1	P38398-1.2	N1488R	Neutral	0.278
BRCA1	P38398-1.2	N1488S	Neutral	0.123
BRCA1	P38398-1.2	N1488T	Neutral	0.114
BRCA1	P38398-1.2	N1488V	Neutral	0.3
BRCA1	P38398-1.2	N1488W	Pathogenic	0.687
BRCA1	P38398-1.2	N1488Y	Neutral	0.4
BRCA1	P38398-1.2	K1489A	Neutral	0.075
BRCA1	P38398-1.2	K1489C	Neutral	0.098
BRCA1	P38398-1.2	K1489D	Neutral	0.046
BRCA1	P38398-1.2	K1489E	Neutral	0.015
BRCA1	P38398-1.2	K1489F	Neutral	0.035
BRCA1	P38398-1.2	K1489G	Neutral	0.151
BRCA1	P38398-1.2	K1489H	Neutral	0.025
BRCA1	P38398-1.2	K1489I	Neutral	0.044
BRCA1	P38398-1.2	K1489L	Neutral	0.031
BRCA1	P38398-1.2	K1489M	Neutral	0.022
BRCA1	P38398-1.2	K1489N	Neutral	0.029
BRCA1	P38398-1.2	K1489P	Neutral	0.046
BRCA1	P38398-1.2	K1489Q	Neutral	0.014
BRCA1	P38398-1.2	K1489R	Neutral	0.008
BRCA1	P38398-1.2	K1489S	Neutral	0.047
BRCA1	P38398-1.2	K1489T	Neutral	0.043
BRCA1	P38398-1.2	K1489V	Neutral	0.047
BRCA1	P38398-1.2	K1489W	Neutral	0.062
BRCA1	P38398-1.2	K1489Y	Neutral	0.028
BRCA1	P38398-1.2	E1490A	Neutral	0.5
BRCA1	P38398-1.2	E1490C	Pathogenic	0.658
BRCA1	P38398-1.2	E1490D	Neutral	0.167
BRCA1	P38398-1.2	E1490F	Pathogenic	0.585
BRCA1	P38398-1.2	E1490G	Pathogenic	0.688
BRCA1	P38398-1.2	E1490H	Neutral	0.251
BRCA1	P38398-1.2	E1490I	Pathogenic	0.525
BRCA1	P38398-1.2	E1490K	Neutral	0.255
BRCA1	P38398-1.2	E1490L	Pathogenic	0.525
BRCA1	P38398-1.2	E1490M	Neutral	0.437
BRCA1	P38398-1.2	E1490N	Neutral	0.271
BRCA1	P38398-1.2	E1490P	Neutral	0.373
BRCA1	P38398-1.2	E1490Q	Neutral	0.13
BRCA1	P38398-1.2	E1490R	Neutral	0.396
BRCA1	P38398-1.2	E1490S	Neutral	0.38
BRCA1	P38398-1.2	E1490T	Neutral	0.36
BRCA1	P38398-1.2	E1490V	Neutral	0.378
BRCA1	P38398-1.2	E1490W	Pathogenic	0.722
BRCA1	P38398-1.2	E1490Y	Pathogenic	0.532
BRCA1	P38398-1.2	P1491A	Neutral	0.096
BRCA1	P38398-1.2	P1491C	Neutral	0.126
BRCA1	P38398-1.2	P1491D	Neutral	0.06
BRCA1	P38398-1.2	P1491E	Neutral	0.087
BRCA1	P38398-1.2	P1491F	Neutral	0.338
BRCA1	P38398-1.2	P1491G	Neutral	0.188
BRCA1	P38398-1.2	P1491H	Neutral	0.146
BRCA1	P38398-1.2	P1491I	Neutral	0.217
BRCA1	P38398-1.2	P1491K	Neutral	0.145
BRCA1	P38398-1.2	P1491L	Neutral	0.218
BRCA1	P38398-1.2	P1491M	Neutral	0.163
BRCA1	P38398-1.2	P1491N	Neutral	0.093
BRCA1	P38398-1.2	P1491Q	Neutral	0.097
BRCA1	P38398-1.2	P1491R	Neutral	0.245
BRCA1	P38398-1.2	P1491S	Neutral	0.085
BRCA1	P38398-1.2	P1491T	Neutral	0.064
BRCA1	P38398-1.2	P1491V	Neutral	0.113
BRCA1	P38398-1.2	P1491W	Neutral	0.485
BRCA1	P38398-1.2	P1491Y	Neutral	0.291
BRCA1	P38398-1.2	G1492A	Neutral	0.132
BRCA1	P38398-1.2	G1492C	Neutral	0.406
BRCA1	P38398-1.2	G1492D	Neutral	0.27
BRCA1	P38398-1.2	G1492E	Neutral	0.444
BRCA1	P38398-1.2	G1492F	Pathogenic	0.667
BRCA1	P38398-1.2	G1492H	Neutral	0.496
BRCA1	P38398-1.2	G1492I	Pathogenic	0.693
BRCA1	P38398-1.2	G1492K	Pathogenic	0.585
BRCA1	P38398-1.2	G1492L	Pathogenic	0.693
BRCA1	P38398-1.2	G1492M	Pathogenic	0.613
BRCA1	P38398-1.2	G1492N	Neutral	0.224
BRCA1	P38398-1.2	G1492P	Neutral	0.343
BRCA1	P38398-1.2	G1492Q	Neutral	0.473
BRCA1	P38398-1.2	G1492R	Pathogenic	0.653
BRCA1	P38398-1.2	G1492S	Neutral	0.149
BRCA1	P38398-1.2	G1492T	Neutral	0.36
BRCA1	P38398-1.2	G1492V	Pathogenic	0.509
BRCA1	P38398-1.2	G1492W	Pathogenic	0.72
BRCA1	P38398-1.2	G1492Y	Pathogenic	0.699
BRCA1	P38398-1.2	V1493A	Neutral	0.011
BRCA1	P38398-1.2	V1493C	Neutral	0.011
BRCA1	P38398-1.2	V1493D	Neutral	0.019
BRCA1	P38398-1.2	V1493E	Neutral	0.011
BRCA1	P38398-1.2	V1493F	Neutral	0.013
BRCA1	P38398-1.2	V1493G	Neutral	0.048
BRCA1	P38398-1.2	V1493H	Neutral	0.019
BRCA1	P38398-1.2	V1493I	Neutral	0.002
BRCA1	P38398-1.2	V1493K	Neutral	0.019
BRCA1	P38398-1.2	V1493L	Neutral	0.005
BRCA1	P38398-1.2	V1493M	Neutral	0.005
BRCA1	P38398-1.2	V1493N	Neutral	0.017
BRCA1	P38398-1.2	V1493P	Neutral	0.014
BRCA1	P38398-1.2	V1493Q	Neutral	0.012
BRCA1	P38398-1.2	V1493R	Neutral	0.035
BRCA1	P38398-1.2	V1493S	Neutral	0.02
BRCA1	P38398-1.2	V1493T	Neutral	0.006
BRCA1	P38398-1.2	V1493W	Neutral	0.05
BRCA1	P38398-1.2	V1493Y	Neutral	0.015
BRCA1	P38398-1.2	E1494A	Neutral	0.018
BRCA1	P38398-1.2	E1494C	Neutral	0.035
BRCA1	P38398-1.2	E1494D	Neutral	0.004
BRCA1	P38398-1.2	E1494F	Neutral	0.026
BRCA1	P38398-1.2	E1494G	Neutral	0.04
BRCA1	P38398-1.2	E1494H	Neutral	0.006
BRCA1	P38398-1.2	E1494I	Neutral	0.02
BRCA1	P38398-1.2	E1494K	Neutral	0.006
BRCA1	P38398-1.2	E1494L	Neutral	0.02
BRCA1	P38398-1.2	E1494M	Neutral	0.014
BRCA1	P38398-1.2	E1494N	Neutral	0.007
BRCA1	P38398-1.2	E1494P	Neutral	0.011
BRCA1	P38398-1.2	E1494Q	Neutral	0.003
BRCA1	P38398-1.2	E1494R	Neutral	0.012
BRCA1	P38398-1.2	E1494S	Neutral	0.011
BRCA1	P38398-1.2	E1494T	Neutral	0.01
BRCA1	P38398-1.2	E1494V	Neutral	0.011
BRCA1	P38398-1.2	E1494W	Neutral	0.046
BRCA1	P38398-1.2	E1494Y	Neutral	0.021
BRCA1	P38398-1.2	R1495A	Pathogenic	0.561
BRCA1	P38398-1.2	R1495C	Pathogenic	0.632
BRCA1	P38398-1.2	R1495D	Pathogenic	0.525
BRCA1	P38398-1.2	R1495E	Neutral	0.263
BRCA1	P38398-1.2	R1495F	Neutral	0.363
BRCA1	P38398-1.2	R1495G	Pathogenic	0.739
BRCA1	P38398-1.2	R1495H	Neutral	0.223
BRCA1	P38398-1.2	R1495I	Neutral	0.421
BRCA1	P38398-1.2	R1495K	Neutral	0.089
BRCA1	P38398-1.2	R1495L	Neutral	0.336
BRCA1	P38398-1.2	R1495M	Neutral	0.262
BRCA1	P38398-1.2	R1495N	Neutral	0.322
BRCA1	P38398-1.2	R1495P	Pathogenic	0.523
BRCA1	P38398-1.2	R1495Q	Neutral	0.18
BRCA1	P38398-1.2	R1495S	Pathogenic	0.53
BRCA1	P38398-1.2	R1495T	Neutral	0.418
BRCA1	P38398-1.2	R1495V	Pathogenic	0.528
BRCA1	P38398-1.2	R1495W	Neutral	0.371
BRCA1	P38398-1.2	R1495Y	Neutral	0.26
BRCA1	P38398-1.2	S1496A	Neutral	0.021
BRCA1	P38398-1.2	S1496C	Neutral	0.048
BRCA1	P38398-1.2	S1496D	Neutral	0.038
BRCA1	P38398-1.2	S1496E	Neutral	0.055
BRCA1	P38398-1.2	S1496F	Neutral	0.174
BRCA1	P38398-1.2	S1496G	Neutral	0.044
BRCA1	P38398-1.2	S1496H	Neutral	0.094
BRCA1	P38398-1.2	S1496I	Neutral	0.142
BRCA1	P38398-1.2	S1496K	Neutral	0.094
BRCA1	P38398-1.2	S1496L	Neutral	0.142
BRCA1	P38398-1.2	S1496M	Neutral	0.104
BRCA1	P38398-1.2	S1496N	Neutral	0.03
BRCA1	P38398-1.2	S1496P	Neutral	0.052
BRCA1	P38398-1.2	S1496Q	Neutral	0.062
BRCA1	P38398-1.2	S1496R	Neutral	0.166
BRCA1	P38398-1.2	S1496T	Neutral	0.028
BRCA1	P38398-1.2	S1496V	Neutral	0.099
BRCA1	P38398-1.2	S1496W	Neutral	0.359
BRCA1	P38398-1.2	S1496Y	Neutral	0.197
BRCA1	P38398-1.2	S1497A	Neutral	0.113
BRCA1	P38398-1.2	S1497C	Neutral	0.234
BRCA1	P38398-1.2	S1497D	Neutral	0.192
BRCA1	P38398-1.2	S1497E	Neutral	0.263
BRCA1	P38398-1.2	S1497F	Pathogenic	0.562
BRCA1	P38398-1.2	S1497G	Neutral	0.22
BRCA1	P38398-1.2	S1497H	Neutral	0.387
BRCA1	P38398-1.2	S1497I	Pathogenic	0.501
BRCA1	P38398-1.2	S1497K	Neutral	0.387
BRCA1	P38398-1.2	S1497L	Pathogenic	0.502
BRCA1	P38398-1.2	S1497M	Neutral	0.414
BRCA1	P38398-1.2	S1497N	Neutral	0.157
BRCA1	P38398-1.2	S1497P	Neutral	0.251
BRCA1	P38398-1.2	S1497Q	Neutral	0.286
BRCA1	P38398-1.2	S1497R	Pathogenic	0.548
BRCA1	P38398-1.2	S1497T	Neutral	0.149
BRCA1	P38398-1.2	S1497V	Neutral	0.4
BRCA1	P38398-1.2	S1497W	Pathogenic	0.773
BRCA1	P38398-1.2	S1497Y	Pathogenic	0.598
BRCA1	P38398-1.2	P1498A	Neutral	0.152
BRCA1	P38398-1.2	P1498C	Neutral	0.196
BRCA1	P38398-1.2	P1498D	Neutral	0.097
BRCA1	P38398-1.2	P1498E	Neutral	0.139
BRCA1	P38398-1.2	P1498F	Neutral	0.462
BRCA1	P38398-1.2	P1498G	Neutral	0.281
BRCA1	P38398-1.2	P1498H	Neutral	0.223
BRCA1	P38398-1.2	P1498I	Neutral	0.319
BRCA1	P38398-1.2	P1498K	Neutral	0.222
BRCA1	P38398-1.2	P1498L	Neutral	0.319
BRCA1	P38398-1.2	P1498M	Neutral	0.247
BRCA1	P38398-1.2	P1498N	Neutral	0.148
BRCA1	P38398-1.2	P1498Q	Neutral	0.153
BRCA1	P38398-1.2	P1498R	Neutral	0.353
BRCA1	P38398-1.2	P1498S	Neutral	0.135
BRCA1	P38398-1.2	P1498T	Neutral	0.103
BRCA1	P38398-1.2	P1498V	Neutral	0.177
BRCA1	P38398-1.2	P1498W	Pathogenic	0.613
BRCA1	P38398-1.2	P1498Y	Neutral	0.409
BRCA1	P38398-1.2	S1499A	Neutral	0.023
BRCA1	P38398-1.2	S1499C	Neutral	0.052
BRCA1	P38398-1.2	S1499D	Neutral	0.041
BRCA1	P38398-1.2	S1499E	Neutral	0.061
BRCA1	P38398-1.2	S1499F	Neutral	0.189
BRCA1	P38398-1.2	S1499G	Neutral	0.049
BRCA1	P38398-1.2	S1499H	Neutral	0.103
BRCA1	P38398-1.2	S1499I	Neutral	0.154
BRCA1	P38398-1.2	S1499K	Neutral	0.102
BRCA1	P38398-1.2	S1499L	Neutral	0.154
BRCA1	P38398-1.2	S1499M	Neutral	0.113
BRCA1	P38398-1.2	S1499N	Neutral	0.032
BRCA1	P38398-1.2	S1499P	Neutral	0.057
BRCA1	P38398-1.2	S1499Q	Neutral	0.068
BRCA1	P38398-1.2	S1499R	Neutral	0.18
BRCA1	P38398-1.2	S1499T	Neutral	0.031
BRCA1	P38398-1.2	S1499V	Neutral	0.108
BRCA1	P38398-1.2	S1499W	Neutral	0.382
BRCA1	P38398-1.2	S1499Y	Neutral	0.212
BRCA1	P38398-1.2	K1500A	Neutral	0.053
BRCA1	P38398-1.2	K1500C	Neutral	0.069
BRCA1	P38398-1.2	K1500D	Neutral	0.032
BRCA1	P38398-1.2	K1500E	Neutral	0.011
BRCA1	P38398-1.2	K1500F	Neutral	0.024
BRCA1	P38398-1.2	K1500G	Neutral	0.109
BRCA1	P38398-1.2	K1500H	Neutral	0.018
BRCA1	P38398-1.2	K1500I	Neutral	0.031
BRCA1	P38398-1.2	K1500L	Neutral	0.022
BRCA1	P38398-1.2	K1500M	Neutral	0.015
BRCA1	P38398-1.2	K1500N	Neutral	0.02
BRCA1	P38398-1.2	K1500P	Neutral	0.032
BRCA1	P38398-1.2	K1500Q	Neutral	0.009
BRCA1	P38398-1.2	K1500R	Neutral	0.006
BRCA1	P38398-1.2	K1500S	Neutral	0.033
BRCA1	P38398-1.2	K1500T	Neutral	0.03
BRCA1	P38398-1.2	K1500V	Neutral	0.033
BRCA1	P38398-1.2	K1500W	Neutral	0.044
BRCA1	P38398-1.2	K1500Y	Neutral	0.02
BRCA1	P38398-1.2	C1501A	Neutral	0.02
BRCA1	P38398-1.2	C1501D	Neutral	0.042
BRCA1	P38398-1.2	C1501E	Neutral	0.087
BRCA1	P38398-1.2	C1501F	Neutral	0.077
BRCA1	P38398-1.2	C1501G	Neutral	0.085
BRCA1	P38398-1.2	C1501H	Neutral	0.076
BRCA1	P38398-1.2	C1501I	Neutral	0.043
BRCA1	P38398-1.2	C1501K	Neutral	0.105
BRCA1	P38398-1.2	C1501L	Neutral	0.043
BRCA1	P38398-1.2	C1501M	Neutral	0.044
BRCA1	P38398-1.2	C1501N	Neutral	0.047
BRCA1	P38398-1.2	C1501P	Neutral	0.043
BRCA1	P38398-1.2	C1501Q	Neutral	0.069
BRCA1	P38398-1.2	C1501R	Neutral	0.135
BRCA1	P38398-1.2	C1501S	Neutral	0.025
BRCA1	P38398-1.2	C1501T	Neutral	0.022
BRCA1	P38398-1.2	C1501V	Neutral	0.029
BRCA1	P38398-1.2	C1501W	Neutral	0.133
BRCA1	P38398-1.2	C1501Y	Neutral	0.088
BRCA1	P38398-1.2	P1502A	Neutral	0.019
BRCA1	P38398-1.2	P1502C	Neutral	0.026
BRCA1	P38398-1.2	P1502D	Neutral	0.011
BRCA1	P38398-1.2	P1502E	Neutral	0.017
BRCA1	P38398-1.2	P1502F	Neutral	0.084
BRCA1	P38398-1.2	P1502G	Neutral	0.04
BRCA1	P38398-1.2	P1502H	Neutral	0.03
BRCA1	P38398-1.2	P1502I	Neutral	0.048
BRCA1	P38398-1.2	P1502K	Neutral	0.03
BRCA1	P38398-1.2	P1502L	Neutral	0.048
BRCA1	P38398-1.2	P1502M	Neutral	0.034
BRCA1	P38398-1.2	P1502N	Neutral	0.018
BRCA1	P38398-1.2	P1502Q	Neutral	0.019
BRCA1	P38398-1.2	P1502R	Neutral	0.055
BRCA1	P38398-1.2	P1502S	Neutral	0.016
BRCA1	P38398-1.2	P1502T	Neutral	0.012
BRCA1	P38398-1.2	P1502V	Neutral	0.023
BRCA1	P38398-1.2	P1502W	Neutral	0.145
BRCA1	P38398-1.2	P1502Y	Neutral	0.069
BRCA1	P38398-1.2	S1503A	Neutral	0.003
BRCA1	P38398-1.2	S1503C	Neutral	0.007
BRCA1	P38398-1.2	S1503D	Neutral	0.005
BRCA1	P38398-1.2	S1503E	Neutral	0.008
BRCA1	P38398-1.2	S1503F	Neutral	0.029
BRCA1	P38398-1.2	S1503G	Neutral	0.006
BRCA1	P38398-1.2	S1503H	Neutral	0.014
BRCA1	P38398-1.2	S1503I	Neutral	0.023
BRCA1	P38398-1.2	S1503K	Neutral	0.014
BRCA1	P38398-1.2	S1503L	Neutral	0.023
BRCA1	P38398-1.2	S1503M	Neutral	0.016
BRCA1	P38398-1.2	S1503N	Neutral	0.004
BRCA1	P38398-1.2	S1503P	Neutral	0.008
BRCA1	P38398-1.2	S1503Q	Neutral	0.009
BRCA1	P38398-1.2	S1503R	Neutral	0.027
BRCA1	P38398-1.2	S1503T	Neutral	0.004
BRCA1	P38398-1.2	S1503V	Neutral	0.015
BRCA1	P38398-1.2	S1503W	Neutral	0.073
BRCA1	P38398-1.2	S1503Y	Neutral	0.033
BRCA1	P38398-1.2	L1504A	Neutral	0.022
BRCA1	P38398-1.2	L1504C	Neutral	0.015
BRCA1	P38398-1.2	L1504D	Neutral	0.037
BRCA1	P38398-1.2	L1504E	Neutral	0.018
BRCA1	P38398-1.2	L1504F	Neutral	0.006
BRCA1	P38398-1.2	L1504G	Neutral	0.093
BRCA1	P38398-1.2	L1504H	Neutral	0.015
BRCA1	P38398-1.2	L1504I	Neutral	0.002
BRCA1	P38398-1.2	L1504K	Neutral	0.011
BRCA1	P38398-1.2	L1504M	Neutral	0.002
BRCA1	P38398-1.2	L1504N	Neutral	0.024
BRCA1	P38398-1.2	L1504P	Neutral	0.028
BRCA1	P38398-1.2	L1504Q	Neutral	0.011
BRCA1	P38398-1.2	L1504R	Neutral	0.015
BRCA1	P38398-1.2	L1504S	Neutral	0.028
BRCA1	P38398-1.2	L1504T	Neutral	0.013
BRCA1	P38398-1.2	L1504V	Neutral	0.005
BRCA1	P38398-1.2	L1504W	Neutral	0.022
BRCA1	P38398-1.2	L1504Y	Neutral	0.009
BRCA1	P38398-1.2	D1505A	Neutral	0.068
BRCA1	P38398-1.2	D1505C	Neutral	0.063
BRCA1	P38398-1.2	D1505E	Neutral	0.015
BRCA1	P38398-1.2	D1505F	Neutral	0.137
BRCA1	P38398-1.2	D1505G	Neutral	0.072
BRCA1	P38398-1.2	D1505H	Neutral	0.051
BRCA1	P38398-1.2	D1505I	Neutral	0.11
BRCA1	P38398-1.2	D1505K	Neutral	0.074
BRCA1	P38398-1.2	D1505L	Neutral	0.152
BRCA1	P38398-1.2	D1505M	Neutral	0.111
BRCA1	P38398-1.2	D1505N	Neutral	0.016
BRCA1	P38398-1.2	D1505P	Neutral	0.029
BRCA1	P38398-1.2	D1505Q	Neutral	0.033
BRCA1	P38398-1.2	D1505R	Neutral	0.133
BRCA1	P38398-1.2	D1505S	Neutral	0.03
BRCA1	P38398-1.2	D1505T	Neutral	0.03
BRCA1	P38398-1.2	D1505V	Neutral	0.076
BRCA1	P38398-1.2	D1505W	Neutral	0.296
BRCA1	P38398-1.2	D1505Y	Neutral	0.155
BRCA1	P38398-1.2	D1506A	Neutral	0.006
BRCA1	P38398-1.2	D1506C	Neutral	0.006
BRCA1	P38398-1.2	D1506E	Neutral	0.001
BRCA1	P38398-1.2	D1506F	Neutral	0.014
BRCA1	P38398-1.2	D1506G	Neutral	0.007
BRCA1	P38398-1.2	D1506H	Neutral	0.005
BRCA1	P38398-1.2	D1506I	Neutral	0.011
BRCA1	P38398-1.2	D1506K	Neutral	0.007
BRCA1	P38398-1.2	D1506L	Neutral	0.015
BRCA1	P38398-1.2	D1506M	Neutral	0.011
BRCA1	P38398-1.2	D1506N	Neutral	0.001
BRCA1	P38398-1.2	D1506P	Neutral	0.003
BRCA1	P38398-1.2	D1506Q	Neutral	0.003
BRCA1	P38398-1.2	D1506R	Neutral	0.013
BRCA1	P38398-1.2	D1506S	Neutral	0.003
BRCA1	P38398-1.2	D1506T	Neutral	0.003
BRCA1	P38398-1.2	D1506V	Neutral	0.007
BRCA1	P38398-1.2	D1506W	Neutral	0.035
BRCA1	P38398-1.2	D1506Y	Neutral	0.016
BRCA1	P38398-1.2	R1507A	Neutral	0.276
BRCA1	P38398-1.2	R1507C	Neutral	0.338
BRCA1	P38398-1.2	R1507D	Neutral	0.247
BRCA1	P38398-1.2	R1507E	Neutral	0.096
BRCA1	P38398-1.2	R1507F	Neutral	0.145
BRCA1	P38398-1.2	R1507G	Neutral	0.457
BRCA1	P38398-1.2	R1507H	Neutral	0.079
BRCA1	P38398-1.2	R1507I	Neutral	0.178
BRCA1	P38398-1.2	R1507K	Neutral	0.028
BRCA1	P38398-1.2	R1507L	Neutral	0.131
BRCA1	P38398-1.2	R1507M	Neutral	0.095
BRCA1	P38398-1.2	R1507N	Neutral	0.124
BRCA1	P38398-1.2	R1507P	Neutral	0.246
BRCA1	P38398-1.2	R1507Q	Neutral	0.061
BRCA1	P38398-1.2	R1507S	Neutral	0.251
BRCA1	P38398-1.2	R1507T	Neutral	0.176
BRCA1	P38398-1.2	R1507V	Neutral	0.25
BRCA1	P38398-1.2	R1507W	Neutral	0.149
BRCA1	P38398-1.2	R1507Y	Neutral	0.095
BRCA1	P38398-1.2	W1508A	Pathogenic	0.938
BRCA1	P38398-1.2	W1508C	Pathogenic	0.875
BRCA1	P38398-1.2	W1508D	Pathogenic	0.926
BRCA1	P38398-1.2	W1508E	Pathogenic	0.854
BRCA1	P38398-1.2	W1508F	Neutral	0.445
BRCA1	P38398-1.2	W1508G	Pathogenic	0.941
BRCA1	P38398-1.2	W1508H	Pathogenic	0.771
BRCA1	P38398-1.2	W1508I	Pathogenic	0.814
BRCA1	P38398-1.2	W1508K	Pathogenic	0.765
BRCA1	P38398-1.2	W1508L	Pathogenic	0.753
BRCA1	P38398-1.2	W1508M	Pathogenic	0.677
BRCA1	P38398-1.2	W1508N	Pathogenic	0.918
BRCA1	P38398-1.2	W1508P	Pathogenic	0.929
BRCA1	P38398-1.2	W1508Q	Pathogenic	0.786
BRCA1	P38398-1.2	W1508R	Pathogenic	0.709
BRCA1	P38398-1.2	W1508S	Pathogenic	0.929
BRCA1	P38398-1.2	W1508T	Pathogenic	0.855
BRCA1	P38398-1.2	W1508V	Pathogenic	0.869
BRCA1	P38398-1.2	W1508Y	Neutral	0.324
BRCA1	P38398-1.2	Y1509A	Neutral	0.193
BRCA1	P38398-1.2	Y1509C	Neutral	0.137
BRCA1	P38398-1.2	Y1509D	Neutral	0.165
BRCA1	P38398-1.2	Y1509E	Neutral	0.085
BRCA1	P38398-1.2	Y1509F	Neutral	0.008
BRCA1	P38398-1.2	Y1509G	Neutral	0.343
BRCA1	P38398-1.2	Y1509H	Neutral	0.018
BRCA1	P38398-1.2	Y1509I	Neutral	0.045
BRCA1	P38398-1.2	Y1509K	Neutral	0.049
BRCA1	P38398-1.2	Y1509L	Neutral	0.045
BRCA1	P38398-1.2	Y1509M	Neutral	0.045
BRCA1	P38398-1.2	Y1509N	Neutral	0.11
BRCA1	P38398-1.2	Y1509P	Neutral	0.173
BRCA1	P38398-1.2	Y1509Q	Neutral	0.055
BRCA1	P38398-1.2	Y1509R	Neutral	0.05
BRCA1	P38398-1.2	Y1509S	Neutral	0.172
BRCA1	P38398-1.2	Y1509T	Neutral	0.118
BRCA1	P38398-1.2	Y1509V	Neutral	0.067
BRCA1	P38398-1.2	Y1509W	Neutral	0.017
BRCA1	P38398-1.2	M1510A	Neutral	0.023
BRCA1	P38398-1.2	M1510C	Neutral	0.016
BRCA1	P38398-1.2	M1510D	Neutral	0.028
BRCA1	P38398-1.2	M1510E	Neutral	0.013
BRCA1	P38398-1.2	M1510F	Neutral	0.006
BRCA1	P38398-1.2	M1510G	Neutral	0.07
BRCA1	P38398-1.2	M1510H	Neutral	0.011
BRCA1	P38398-1.2	M1510I	Neutral	0.003
BRCA1	P38398-1.2	M1510K	Neutral	0.008
BRCA1	P38398-1.2	M1510L	Neutral	0.002
BRCA1	P38398-1.2	M1510N	Neutral	0.017
BRCA1	P38398-1.2	M1510P	Neutral	0.02
BRCA1	P38398-1.2	M1510Q	Neutral	0.006
BRCA1	P38398-1.2	M1510R	Neutral	0.011
BRCA1	P38398-1.2	M1510S	Neutral	0.02
BRCA1	P38398-1.2	M1510T	Neutral	0.013
BRCA1	P38398-1.2	M1510V	Neutral	0.005
BRCA1	P38398-1.2	M1510W	Neutral	0.016
BRCA1	P38398-1.2	M1510Y	Neutral	0.01
BRCA1	P38398-1.2	H1511A	Neutral	0.412
BRCA1	P38398-1.2	H1511C	Neutral	0.395
BRCA1	P38398-1.2	H1511D	Neutral	0.22
BRCA1	P38398-1.2	H1511E	Neutral	0.116
BRCA1	P38398-1.2	H1511F	Neutral	0.182
BRCA1	P38398-1.2	H1511G	Pathogenic	0.516
BRCA1	P38398-1.2	H1511I	Neutral	0.265
BRCA1	P38398-1.2	H1511K	Neutral	0.183
BRCA1	P38398-1.2	H1511L	Neutral	0.265
BRCA1	P38398-1.2	H1511M	Neutral	0.202
BRCA1	P38398-1.2	H1511N	Neutral	0.109
BRCA1	P38398-1.2	H1511P	Neutral	0.294
BRCA1	P38398-1.2	H1511Q	Neutral	0.106
BRCA1	P38398-1.2	H1511R	Neutral	0.172
BRCA1	P38398-1.2	H1511S	Neutral	0.299
BRCA1	P38398-1.2	H1511T	Neutral	0.282
BRCA1	P38398-1.2	H1511V	Neutral	0.299
BRCA1	P38398-1.2	H1511W	Neutral	0.371
BRCA1	P38398-1.2	H1511Y	Neutral	0.08
BRCA1	P38398-1.2	S1512A	Neutral	0.048
BRCA1	P38398-1.2	S1512C	Neutral	0.107
BRCA1	P38398-1.2	S1512D	Neutral	0.085
BRCA1	P38398-1.2	S1512E	Neutral	0.122
BRCA1	P38398-1.2	S1512F	Neutral	0.335
BRCA1	P38398-1.2	S1512G	Neutral	0.1
BRCA1	P38398-1.2	S1512H	Neutral	0.198
BRCA1	P38398-1.2	S1512I	Neutral	0.283
BRCA1	P38398-1.2	S1512K	Neutral	0.198
BRCA1	P38398-1.2	S1512L	Neutral	0.283
BRCA1	P38398-1.2	S1512M	Neutral	0.217
BRCA1	P38398-1.2	S1512N	Neutral	0.068
BRCA1	P38398-1.2	S1512P	Neutral	0.116
BRCA1	P38398-1.2	S1512Q	Neutral	0.136
BRCA1	P38398-1.2	S1512R	Neutral	0.322
BRCA1	P38398-1.2	S1512T	Neutral	0.064
BRCA1	P38398-1.2	S1512V	Neutral	0.207
BRCA1	P38398-1.2	S1512W	Pathogenic	0.572
BRCA1	P38398-1.2	S1512Y	Neutral	0.369
BRCA1	P38398-1.2	C1513A	Neutral	0.002
BRCA1	P38398-1.2	C1513D	Neutral	0.004
BRCA1	P38398-1.2	C1513E	Neutral	0.008
BRCA1	P38398-1.2	C1513F	Neutral	0.007
BRCA1	P38398-1.2	C1513G	Neutral	0.008
BRCA1	P38398-1.2	C1513H	Neutral	0.007
BRCA1	P38398-1.2	C1513I	Neutral	0.004
BRCA1	P38398-1.2	C1513K	Neutral	0.01
BRCA1	P38398-1.2	C1513L	Neutral	0.004
BRCA1	P38398-1.2	C1513M	Neutral	0.004
BRCA1	P38398-1.2	C1513N	Neutral	0.004
BRCA1	P38398-1.2	C1513P	Neutral	0.004
BRCA1	P38398-1.2	C1513Q	Neutral	0.007
BRCA1	P38398-1.2	C1513R	Neutral	0.014
BRCA1	P38398-1.2	C1513S	Neutral	0.002
BRCA1	P38398-1.2	C1513T	Neutral	0.002
BRCA1	P38398-1.2	C1513V	Neutral	0.003
BRCA1	P38398-1.2	C1513W	Neutral	0.013
BRCA1	P38398-1.2	C1513Y	Neutral	0.008
BRCA1	P38398-1.2	S1514A	Neutral	0.034
BRCA1	P38398-1.2	S1514C	Neutral	0.077
BRCA1	P38398-1.2	S1514D	Neutral	0.061
BRCA1	P38398-1.2	S1514E	Neutral	0.089
BRCA1	P38398-1.2	S1514F	Neutral	0.26
BRCA1	P38398-1.2	S1514G	Neutral	0.072
BRCA1	P38398-1.2	S1514H	Neutral	0.147
BRCA1	P38398-1.2	S1514I	Neutral	0.216
BRCA1	P38398-1.2	S1514K	Neutral	0.147
BRCA1	P38398-1.2	S1514L	Neutral	0.216
BRCA1	P38398-1.2	S1514M	Neutral	0.162
BRCA1	P38398-1.2	S1514N	Neutral	0.048
BRCA1	P38398-1.2	S1514P	Neutral	0.084
BRCA1	P38398-1.2	S1514Q	Neutral	0.099
BRCA1	P38398-1.2	S1514R	Neutral	0.249
BRCA1	P38398-1.2	S1514T	Neutral	0.046
BRCA1	P38398-1.2	S1514V	Neutral	0.154
BRCA1	P38398-1.2	S1514W	Neutral	0.482
BRCA1	P38398-1.2	S1514Y	Neutral	0.289
BRCA1	P38398-1.2	G1515A	Neutral	0.012
BRCA1	P38398-1.2	G1515C	Neutral	0.053
BRCA1	P38398-1.2	G1515D	Neutral	0.029
BRCA1	P38398-1.2	G1515E	Neutral	0.061
BRCA1	P38398-1.2	G1515F	Neutral	0.141
BRCA1	P38398-1.2	G1515H	Neutral	0.074
BRCA1	P38398-1.2	G1515I	Neutral	0.156
BRCA1	P38398-1.2	G1515K	Neutral	0.104
BRCA1	P38398-1.2	G1515L	Neutral	0.156
BRCA1	P38398-1.2	G1515M	Neutral	0.115
BRCA1	P38398-1.2	G1515N	Neutral	0.023
BRCA1	P38398-1.2	G1515P	Neutral	0.041
BRCA1	P38398-1.2	G1515Q	Neutral	0.068
BRCA1	P38398-1.2	G1515R	Neutral	0.133
BRCA1	P38398-1.2	G1515S	Neutral	0.014
BRCA1	P38398-1.2	G1515T	Neutral	0.044
BRCA1	P38398-1.2	G1515V	Neutral	0.078
BRCA1	P38398-1.2	G1515W	Neutral	0.173
BRCA1	P38398-1.2	G1515Y	Neutral	0.16
BRCA1	P38398-1.2	S1516A	Neutral	0.005
BRCA1	P38398-1.2	S1516C	Neutral	0.013
BRCA1	P38398-1.2	S1516D	Neutral	0.01
BRCA1	P38398-1.2	S1516E	Neutral	0.015
BRCA1	P38398-1.2	S1516F	Neutral	0.051
BRCA1	P38398-1.2	S1516G	Neutral	0.012
BRCA1	P38398-1.2	S1516H	Neutral	0.026
BRCA1	P38398-1.2	S1516I	Neutral	0.04
BRCA1	P38398-1.2	S1516K	Neutral	0.026
BRCA1	P38398-1.2	S1516L	Neutral	0.04
BRCA1	P38398-1.2	S1516M	Neutral	0.029
BRCA1	P38398-1.2	S1516N	Neutral	0.008
BRCA1	P38398-1.2	S1516P	Neutral	0.014
BRCA1	P38398-1.2	S1516Q	Neutral	0.017
BRCA1	P38398-1.2	S1516R	Neutral	0.048
BRCA1	P38398-1.2	S1516T	Neutral	0.007
BRCA1	P38398-1.2	S1516V	Neutral	0.027
BRCA1	P38398-1.2	S1516W	Neutral	0.125
BRCA1	P38398-1.2	S1516Y	Neutral	0.059
BRCA1	P38398-1.2	L1517A	Neutral	0.423
BRCA1	P38398-1.2	L1517C	Neutral	0.327
BRCA1	P38398-1.2	L1517D	Pathogenic	0.557
BRCA1	P38398-1.2	L1517E	Neutral	0.37
BRCA1	P38398-1.2	L1517F	Neutral	0.158
BRCA1	P38398-1.2	L1517G	Pathogenic	0.768
BRCA1	P38398-1.2	L1517H	Neutral	0.328
BRCA1	P38398-1.2	L1517I	Neutral	0.066
BRCA1	P38398-1.2	L1517K	Neutral	0.27
BRCA1	P38398-1.2	L1517M	Neutral	0.066
BRCA1	P38398-1.2	L1517N	Neutral	0.439
BRCA1	P38398-1.2	L1517P	Neutral	0.479
BRCA1	P38398-1.2	L1517Q	Neutral	0.269
BRCA1	P38398-1.2	L1517R	Neutral	0.331
BRCA1	P38398-1.2	L1517S	Neutral	0.478
BRCA1	P38398-1.2	L1517T	Neutral	0.291
BRCA1	P38398-1.2	L1517V	Neutral	0.134
BRCA1	P38398-1.2	L1517W	Neutral	0.418
BRCA1	P38398-1.2	L1517Y	Neutral	0.234
BRCA1	P38398-1.2	Q1518A	Neutral	0.116
BRCA1	P38398-1.2	Q1518C	Neutral	0.15
BRCA1	P38398-1.2	Q1518D	Neutral	0.051
BRCA1	P38398-1.2	Q1518E	Neutral	0.017
BRCA1	P38398-1.2	Q1518F	Neutral	0.129
BRCA1	P38398-1.2	Q1518G	Neutral	0.225
BRCA1	P38398-1.2	Q1518H	Neutral	0.034
BRCA1	P38398-1.2	Q1518I	Neutral	0.104
BRCA1	P38398-1.2	Q1518K	Neutral	0.034
BRCA1	P38398-1.2	Q1518L	Neutral	0.075
BRCA1	P38398-1.2	Q1518M	Neutral	0.038
BRCA1	P38398-1.2	Q1518N	Neutral	0.046
BRCA1	P38398-1.2	Q1518P	Neutral	0.072
BRCA1	P38398-1.2	Q1518R	Neutral	0.045
BRCA1	P38398-1.2	Q1518S	Neutral	0.074
BRCA1	P38398-1.2	Q1518T	Neutral	0.069
BRCA1	P38398-1.2	Q1518V	Neutral	0.074
BRCA1	P38398-1.2	Q1518W	Neutral	0.16
BRCA1	P38398-1.2	Q1518Y	Neutral	0.077
BRCA1	P38398-1.2	N1519A	Neutral	0.048
BRCA1	P38398-1.2	N1519C	Neutral	0.045
BRCA1	P38398-1.2	N1519D	Neutral	0.01
BRCA1	P38398-1.2	N1519E	Neutral	0.017
BRCA1	P38398-1.2	N1519F	Neutral	0.081
BRCA1	P38398-1.2	N1519G	Neutral	0.036
BRCA1	P38398-1.2	N1519H	Neutral	0.014
BRCA1	P38398-1.2	N1519I	Neutral	0.064
BRCA1	P38398-1.2	N1519K	Neutral	0.03
BRCA1	P38398-1.2	N1519L	Neutral	0.064
BRCA1	P38398-1.2	N1519M	Neutral	0.046
BRCA1	P38398-1.2	N1519P	Neutral	0.029
BRCA1	P38398-1.2	N1519Q	Neutral	0.019
BRCA1	P38398-1.2	N1519R	Neutral	0.039
BRCA1	P38398-1.2	N1519S	Neutral	0.015
BRCA1	P38398-1.2	N1519T	Neutral	0.013
BRCA1	P38398-1.2	N1519V	Neutral	0.043
BRCA1	P38398-1.2	N1519W	Neutral	0.189
BRCA1	P38398-1.2	N1519Y	Neutral	0.066
BRCA1	P38398-1.2	R1520A	Neutral	0.155
BRCA1	P38398-1.2	R1520C	Neutral	0.198
BRCA1	P38398-1.2	R1520D	Neutral	0.137
BRCA1	P38398-1.2	R1520E	Neutral	0.049
BRCA1	P38398-1.2	R1520F	Neutral	0.076
BRCA1	P38398-1.2	R1520G	Neutral	0.289
BRCA1	P38398-1.2	R1520H	Neutral	0.04
BRCA1	P38398-1.2	R1520I	Neutral	0.094
BRCA1	P38398-1.2	R1520K	Neutral	0.014
BRCA1	P38398-1.2	R1520L	Neutral	0.068
BRCA1	P38398-1.2	R1520M	Neutral	0.048
BRCA1	P38398-1.2	R1520N	Neutral	0.064
BRCA1	P38398-1.2	R1520P	Neutral	0.136
BRCA1	P38398-1.2	R1520Q	Neutral	0.031
BRCA1	P38398-1.2	R1520S	Neutral	0.139
BRCA1	P38398-1.2	R1520T	Neutral	0.094
BRCA1	P38398-1.2	R1520V	Neutral	0.139
BRCA1	P38398-1.2	R1520W	Neutral	0.078
BRCA1	P38398-1.2	R1520Y	Neutral	0.048
BRCA1	P38398-1.2	N1521A	Neutral	0.054
BRCA1	P38398-1.2	N1521C	Neutral	0.051
BRCA1	P38398-1.2	N1521D	Neutral	0.011
BRCA1	P38398-1.2	N1521E	Neutral	0.019
BRCA1	P38398-1.2	N1521F	Neutral	0.091
BRCA1	P38398-1.2	N1521G	Neutral	0.041
BRCA1	P38398-1.2	N1521H	Neutral	0.016
BRCA1	P38398-1.2	N1521I	Neutral	0.073
BRCA1	P38398-1.2	N1521K	Neutral	0.034
BRCA1	P38398-1.2	N1521L	Neutral	0.073
BRCA1	P38398-1.2	N1521M	Neutral	0.052
BRCA1	P38398-1.2	N1521P	Neutral	0.033
BRCA1	P38398-1.2	N1521Q	Neutral	0.021
BRCA1	P38398-1.2	N1521R	Neutral	0.045
BRCA1	P38398-1.2	N1521S	Neutral	0.017
BRCA1	P38398-1.2	N1521T	Neutral	0.015
BRCA1	P38398-1.2	N1521V	Neutral	0.049
BRCA1	P38398-1.2	N1521W	Neutral	0.21
BRCA1	P38398-1.2	N1521Y	Neutral	0.075
BRCA1	P38398-1.2	Y1522A	Neutral	0.031
BRCA1	P38398-1.2	Y1522C	Neutral	0.021
BRCA1	P38398-1.2	Y1522D	Neutral	0.026
BRCA1	P38398-1.2	Y1522E	Neutral	0.012
BRCA1	P38398-1.2	Y1522F	Neutral	0.001
BRCA1	P38398-1.2	Y1522G	Neutral	0.066
BRCA1	P38398-1.2	Y1522H	Neutral	0.002
BRCA1	P38398-1.2	Y1522I	Neutral	0.006
BRCA1	P38398-1.2	Y1522K	Neutral	0.007
BRCA1	P38398-1.2	Y1522L	Neutral	0.006
BRCA1	P38398-1.2	Y1522M	Neutral	0.006
BRCA1	P38398-1.2	Y1522N	Neutral	0.017
BRCA1	P38398-1.2	Y1522P	Neutral	0.028
BRCA1	P38398-1.2	Y1522Q	Neutral	0.008
BRCA1	P38398-1.2	Y1522R	Neutral	0.007
BRCA1	P38398-1.2	Y1522S	Neutral	0.027
BRCA1	P38398-1.2	Y1522T	Neutral	0.018
BRCA1	P38398-1.2	Y1522V	Neutral	0.01
BRCA1	P38398-1.2	Y1522W	Neutral	0.002
BRCA1	P38398-1.2	P1523A	Neutral	0.231
BRCA1	P38398-1.2	P1523C	Neutral	0.291
BRCA1	P38398-1.2	P1523D	Neutral	0.153
BRCA1	P38398-1.2	P1523E	Neutral	0.213
BRCA1	P38398-1.2	P1523F	Pathogenic	0.591
BRCA1	P38398-1.2	P1523G	Neutral	0.396
BRCA1	P38398-1.2	P1523H	Neutral	0.325
BRCA1	P38398-1.2	P1523I	Neutral	0.44
BRCA1	P38398-1.2	P1523K	Neutral	0.324
BRCA1	P38398-1.2	P1523L	Neutral	0.44
BRCA1	P38398-1.2	P1523M	Neutral	0.356
BRCA1	P38398-1.2	P1523N	Neutral	0.226
BRCA1	P38398-1.2	P1523Q	Neutral	0.233
BRCA1	P38398-1.2	P1523R	Neutral	0.479
BRCA1	P38398-1.2	P1523S	Neutral	0.207
BRCA1	P38398-1.2	P1523T	Neutral	0.162
BRCA1	P38398-1.2	P1523V	Neutral	0.266
BRCA1	P38398-1.2	P1523W	Pathogenic	0.727
BRCA1	P38398-1.2	P1523Y	Pathogenic	0.538
BRCA1	P38398-1.2	S1524A	Neutral	0.026
BRCA1	P38398-1.2	S1524C	Neutral	0.061
BRCA1	P38398-1.2	S1524D	Neutral	0.048
BRCA1	P38398-1.2	S1524E	Neutral	0.07
BRCA1	P38398-1.2	S1524F	Neutral	0.214
BRCA1	P38398-1.2	S1524G	Neutral	0.057
BRCA1	P38398-1.2	S1524H	Neutral	0.118
BRCA1	P38398-1.2	S1524I	Neutral	0.176
BRCA1	P38398-1.2	S1524K	Neutral	0.118
BRCA1	P38398-1.2	S1524L	Neutral	0.176
BRCA1	P38398-1.2	S1524M	Neutral	0.13
BRCA1	P38398-1.2	S1524N	Neutral	0.038
BRCA1	P38398-1.2	S1524P	Neutral	0.066
BRCA1	P38398-1.2	S1524Q	Neutral	0.079
BRCA1	P38398-1.2	S1524R	Neutral	0.204
BRCA1	P38398-1.2	S1524T	Neutral	0.036
BRCA1	P38398-1.2	S1524V	Neutral	0.124
BRCA1	P38398-1.2	S1524W	Neutral	0.42
BRCA1	P38398-1.2	S1524Y	Neutral	0.24
BRCA1	P38398-1.2	Q1525A	Neutral	0.081
BRCA1	P38398-1.2	Q1525C	Neutral	0.106
BRCA1	P38398-1.2	Q1525D	Neutral	0.035
BRCA1	P38398-1.2	Q1525E	Neutral	0.012
BRCA1	P38398-1.2	Q1525F	Neutral	0.091
BRCA1	P38398-1.2	Q1525G	Neutral	0.163
BRCA1	P38398-1.2	Q1525H	Neutral	0.023
BRCA1	P38398-1.2	Q1525I	Neutral	0.072
BRCA1	P38398-1.2	Q1525K	Neutral	0.023
BRCA1	P38398-1.2	Q1525L	Neutral	0.052
BRCA1	P38398-1.2	Q1525M	Neutral	0.026
BRCA1	P38398-1.2	Q1525N	Neutral	0.031
BRCA1	P38398-1.2	Q1525P	Neutral	0.05
BRCA1	P38398-1.2	Q1525R	Neutral	0.031
BRCA1	P38398-1.2	Q1525S	Neutral	0.051
BRCA1	P38398-1.2	Q1525T	Neutral	0.047
BRCA1	P38398-1.2	Q1525V	Neutral	0.051
BRCA1	P38398-1.2	Q1525W	Neutral	0.113
BRCA1	P38398-1.2	Q1525Y	Neutral	0.053
BRCA1	P38398-1.2	E1526A	Neutral	0.051
BRCA1	P38398-1.2	E1526C	Neutral	0.094
BRCA1	P38398-1.2	E1526D	Neutral	0.011
BRCA1	P38398-1.2	E1526F	Neutral	0.071
BRCA1	P38398-1.2	E1526G	Neutral	0.106
BRCA1	P38398-1.2	E1526H	Neutral	0.018
BRCA1	P38398-1.2	E1526I	Neutral	0.056
BRCA1	P38398-1.2	E1526K	Neutral	0.018
BRCA1	P38398-1.2	E1526L	Neutral	0.056
BRCA1	P38398-1.2	E1526M	Neutral	0.04
BRCA1	P38398-1.2	E1526N	Neutral	0.02
BRCA1	P38398-1.2	E1526P	Neutral	0.031
BRCA1	P38398-1.2	E1526Q	Neutral	0.008
BRCA1	P38398-1.2	E1526R	Neutral	0.034
BRCA1	P38398-1.2	E1526S	Neutral	0.032
BRCA1	P38398-1.2	E1526T	Neutral	0.029
BRCA1	P38398-1.2	E1526V	Neutral	0.032
BRCA1	P38398-1.2	E1526W	Neutral	0.123
BRCA1	P38398-1.2	E1526Y	Neutral	0.058
BRCA1	P38398-1.2	E1527A	Neutral	0.026
BRCA1	P38398-1.2	E1527C	Neutral	0.049
BRCA1	P38398-1.2	E1527D	Neutral	0.005
BRCA1	P38398-1.2	E1527F	Neutral	0.036
BRCA1	P38398-1.2	E1527G	Neutral	0.055
BRCA1	P38398-1.2	E1527H	Neutral	0.009
BRCA1	P38398-1.2	E1527I	Neutral	0.028
BRCA1	P38398-1.2	E1527K	Neutral	0.009
BRCA1	P38398-1.2	E1527L	Neutral	0.029
BRCA1	P38398-1.2	E1527M	Neutral	0.02
BRCA1	P38398-1.2	E1527N	Neutral	0.01
BRCA1	P38398-1.2	E1527P	Neutral	0.016
BRCA1	P38398-1.2	E1527Q	Neutral	0.004
BRCA1	P38398-1.2	E1527R	Neutral	0.017
BRCA1	P38398-1.2	E1527S	Neutral	0.016
BRCA1	P38398-1.2	E1527T	Neutral	0.015
BRCA1	P38398-1.2	E1527V	Neutral	0.016
BRCA1	P38398-1.2	E1527W	Neutral	0.065
BRCA1	P38398-1.2	E1527Y	Neutral	0.029
BRCA1	P38398-1.2	L1528A	Neutral	0.069
BRCA1	P38398-1.2	L1528C	Neutral	0.047
BRCA1	P38398-1.2	L1528D	Neutral	0.113
BRCA1	P38398-1.2	L1528E	Neutral	0.056
BRCA1	P38398-1.2	L1528F	Neutral	0.019
BRCA1	P38398-1.2	L1528G	Neutral	0.251
BRCA1	P38398-1.2	L1528H	Neutral	0.047
BRCA1	P38398-1.2	L1528I	Neutral	0.007
BRCA1	P38398-1.2	L1528K	Neutral	0.036
BRCA1	P38398-1.2	L1528M	Neutral	0.007
BRCA1	P38398-1.2	L1528N	Neutral	0.073
BRCA1	P38398-1.2	L1528P	Neutral	0.085
BRCA1	P38398-1.2	L1528Q	Neutral	0.036
BRCA1	P38398-1.2	L1528R	Neutral	0.048
BRCA1	P38398-1.2	L1528S	Neutral	0.085
BRCA1	P38398-1.2	L1528T	Neutral	0.04
BRCA1	P38398-1.2	L1528V	Neutral	0.015
BRCA1	P38398-1.2	L1528W	Neutral	0.068
BRCA1	P38398-1.2	L1528Y	Neutral	0.03
BRCA1	P38398-1.2	I1529A	Neutral	0.006
BRCA1	P38398-1.2	I1529C	Neutral	0.004
BRCA1	P38398-1.2	I1529D	Neutral	0.007
BRCA1	P38398-1.2	I1529E	Neutral	0.005
BRCA1	P38398-1.2	I1529F	Neutral	0.002
BRCA1	P38398-1.2	I1529G	Neutral	0.027
BRCA1	P38398-1.2	I1529H	Neutral	0.004
BRCA1	P38398-1.2	I1529K	Neutral	0.004
BRCA1	P38398-1.2	I1529L	Neutral	0.001
BRCA1	P38398-1.2	I1529M	Neutral	0.001
BRCA1	P38398-1.2	I1529N	Neutral	0.007
BRCA1	P38398-1.2	I1529P	Neutral	0.008
BRCA1	P38398-1.2	I1529Q	Neutral	0.004
BRCA1	P38398-1.2	I1529R	Neutral	0.006
BRCA1	P38398-1.2	I1529S	Neutral	0.008
BRCA1	P38398-1.2	I1529T	Neutral	0.003
BRCA1	P38398-1.2	I1529V	Neutral	0.001
BRCA1	P38398-1.2	I1529W	Neutral	0.009
BRCA1	P38398-1.2	I1529Y	Neutral	0.003
BRCA1	P38398-1.2	K1530A	Neutral	0.014
BRCA1	P38398-1.2	K1530C	Neutral	0.019
BRCA1	P38398-1.2	K1530D	Neutral	0.009
BRCA1	P38398-1.2	K1530E	Neutral	0.003
BRCA1	P38398-1.2	K1530F	Neutral	0.006
BRCA1	P38398-1.2	K1530G	Neutral	0.031
BRCA1	P38398-1.2	K1530H	Neutral	0.005
BRCA1	P38398-1.2	K1530I	Neutral	0.008
BRCA1	P38398-1.2	K1530L	Neutral	0.006
BRCA1	P38398-1.2	K1530M	Neutral	0.004
BRCA1	P38398-1.2	K1530N	Neutral	0.005
BRCA1	P38398-1.2	K1530P	Neutral	0.009
BRCA1	P38398-1.2	K1530Q	Neutral	0.003
BRCA1	P38398-1.2	K1530R	Neutral	0.001
BRCA1	P38398-1.2	K1530S	Neutral	0.009
BRCA1	P38398-1.2	K1530T	Neutral	0.008
BRCA1	P38398-1.2	K1530V	Neutral	0.009
BRCA1	P38398-1.2	K1530W	Neutral	0.012
BRCA1	P38398-1.2	K1530Y	Neutral	0.005
BRCA1	P38398-1.2	V1531A	Neutral	0.01
BRCA1	P38398-1.2	V1531C	Neutral	0.009
BRCA1	P38398-1.2	V1531D	Neutral	0.016
BRCA1	P38398-1.2	V1531E	Neutral	0.009
BRCA1	P38398-1.2	V1531F	Neutral	0.012
BRCA1	P38398-1.2	V1531G	Neutral	0.042
BRCA1	P38398-1.2	V1531H	Neutral	0.016
BRCA1	P38398-1.2	V1531I	Neutral	0.002
BRCA1	P38398-1.2	V1531K	Neutral	0.016
BRCA1	P38398-1.2	V1531L	Neutral	0.004
BRCA1	P38398-1.2	V1531M	Neutral	0.004
BRCA1	P38398-1.2	V1531N	Neutral	0.015
BRCA1	P38398-1.2	V1531P	Neutral	0.012
BRCA1	P38398-1.2	V1531Q	Neutral	0.01
BRCA1	P38398-1.2	V1531R	Neutral	0.03
BRCA1	P38398-1.2	V1531S	Neutral	0.017
BRCA1	P38398-1.2	V1531T	Neutral	0.005
BRCA1	P38398-1.2	V1531W	Neutral	0.043
BRCA1	P38398-1.2	V1531Y	Neutral	0.013
BRCA1	P38398-1.2	V1532A	Neutral	0.023
BRCA1	P38398-1.2	V1532C	Neutral	0.022
BRCA1	P38398-1.2	V1532D	Neutral	0.04
BRCA1	P38398-1.2	V1532E	Neutral	0.022
BRCA1	P38398-1.2	V1532F	Neutral	0.028
BRCA1	P38398-1.2	V1532G	Neutral	0.098
BRCA1	P38398-1.2	V1532H	Neutral	0.039
BRCA1	P38398-1.2	V1532I	Neutral	0.005
BRCA1	P38398-1.2	V1532K	Neutral	0.039
BRCA1	P38398-1.2	V1532L	Neutral	0.011
BRCA1	P38398-1.2	V1532M	Neutral	0.011
BRCA1	P38398-1.2	V1532N	Neutral	0.036
BRCA1	P38398-1.2	V1532P	Neutral	0.029
BRCA1	P38398-1.2	V1532Q	Neutral	0.025
BRCA1	P38398-1.2	V1532R	Neutral	0.072
BRCA1	P38398-1.2	V1532S	Neutral	0.041
BRCA1	P38398-1.2	V1532T	Neutral	0.013
BRCA1	P38398-1.2	V1532W	Neutral	0.1
BRCA1	P38398-1.2	V1532Y	Neutral	0.032
BRCA1	P38398-1.2	D1533A	Neutral	0.009
BRCA1	P38398-1.2	D1533C	Neutral	0.008
BRCA1	P38398-1.2	D1533E	Neutral	0.002
BRCA1	P38398-1.2	D1533F	Neutral	0.019
BRCA1	P38398-1.2	D1533G	Neutral	0.009
BRCA1	P38398-1.2	D1533H	Neutral	0.006
BRCA1	P38398-1.2	D1533I	Neutral	0.015
BRCA1	P38398-1.2	D1533K	Neutral	0.009
BRCA1	P38398-1.2	D1533L	Neutral	0.021
BRCA1	P38398-1.2	D1533M	Neutral	0.015
BRCA1	P38398-1.2	D1533N	Neutral	0.002
BRCA1	P38398-1.2	D1533P	Neutral	0.004
BRCA1	P38398-1.2	D1533Q	Neutral	0.004
BRCA1	P38398-1.2	D1533R	Neutral	0.018
BRCA1	P38398-1.2	D1533S	Neutral	0.004
BRCA1	P38398-1.2	D1533T	Neutral	0.004
BRCA1	P38398-1.2	D1533V	Neutral	0.01
BRCA1	P38398-1.2	D1533W	Neutral	0.048
BRCA1	P38398-1.2	D1533Y	Neutral	0.021
BRCA1	P38398-1.2	V1534A	Neutral	0.012
BRCA1	P38398-1.2	V1534C	Neutral	0.011
BRCA1	P38398-1.2	V1534D	Neutral	0.02
BRCA1	P38398-1.2	V1534E	Neutral	0.011
BRCA1	P38398-1.2	V1534F	Neutral	0.014
BRCA1	P38398-1.2	V1534G	Neutral	0.05
BRCA1	P38398-1.2	V1534H	Neutral	0.02
BRCA1	P38398-1.2	V1534I	Neutral	0.003
BRCA1	P38398-1.2	V1534K	Neutral	0.019
BRCA1	P38398-1.2	V1534L	Neutral	0.005
BRCA1	P38398-1.2	V1534M	Neutral	0.005
BRCA1	P38398-1.2	V1534N	Neutral	0.018
BRCA1	P38398-1.2	V1534P	Neutral	0.014
BRCA1	P38398-1.2	V1534Q	Neutral	0.012
BRCA1	P38398-1.2	V1534R	Neutral	0.037
BRCA1	P38398-1.2	V1534S	Neutral	0.021
BRCA1	P38398-1.2	V1534T	Neutral	0.007
BRCA1	P38398-1.2	V1534W	Neutral	0.052
BRCA1	P38398-1.2	V1534Y	Neutral	0.016
BRCA1	P38398-1.2	E1535A	Neutral	0.267
BRCA1	P38398-1.2	E1535C	Neutral	0.413
BRCA1	P38398-1.2	E1535D	Neutral	0.068
BRCA1	P38398-1.2	E1535F	Neutral	0.339
BRCA1	P38398-1.2	E1535G	Neutral	0.446
BRCA1	P38398-1.2	E1535H	Neutral	0.109
BRCA1	P38398-1.2	E1535I	Neutral	0.287
BRCA1	P38398-1.2	E1535K	Neutral	0.111
BRCA1	P38398-1.2	E1535L	Neutral	0.287
BRCA1	P38398-1.2	E1535M	Neutral	0.22
BRCA1	P38398-1.2	E1535N	Neutral	0.119
BRCA1	P38398-1.2	E1535P	Neutral	0.178
BRCA1	P38398-1.2	E1535Q	Neutral	0.051
BRCA1	P38398-1.2	E1535R	Neutral	0.193
BRCA1	P38398-1.2	E1535S	Neutral	0.182
BRCA1	P38398-1.2	E1535T	Neutral	0.17
BRCA1	P38398-1.2	E1535V	Neutral	0.181
BRCA1	P38398-1.2	E1535W	Neutral	0.487
BRCA1	P38398-1.2	E1535Y	Neutral	0.293
BRCA1	P38398-1.2	E1536A	Neutral	0.184
BRCA1	P38398-1.2	E1536C	Neutral	0.303
BRCA1	P38398-1.2	E1536D	Neutral	0.043
BRCA1	P38398-1.2	E1536F	Neutral	0.241
BRCA1	P38398-1.2	E1536G	Neutral	0.332
BRCA1	P38398-1.2	E1536H	Neutral	0.07
BRCA1	P38398-1.2	E1536I	Neutral	0.199
BRCA1	P38398-1.2	E1536K	Neutral	0.072
BRCA1	P38398-1.2	E1536L	Neutral	0.199
BRCA1	P38398-1.2	E1536M	Neutral	0.149
BRCA1	P38398-1.2	E1536N	Neutral	0.077
BRCA1	P38398-1.2	E1536P	Neutral	0.118
BRCA1	P38398-1.2	E1536Q	Neutral	0.032
BRCA1	P38398-1.2	E1536R	Neutral	0.129
BRCA1	P38398-1.2	E1536S	Neutral	0.121
BRCA1	P38398-1.2	E1536T	Neutral	0.112
BRCA1	P38398-1.2	E1536V	Neutral	0.12
BRCA1	P38398-1.2	E1536W	Neutral	0.37
BRCA1	P38398-1.2	E1536Y	Neutral	0.204
BRCA1	P38398-1.2	Q1537A	Neutral	0.057
BRCA1	P38398-1.2	Q1537C	Neutral	0.075
BRCA1	P38398-1.2	Q1537D	Neutral	0.024
BRCA1	P38398-1.2	Q1537E	Neutral	0.008
BRCA1	P38398-1.2	Q1537F	Neutral	0.064
BRCA1	P38398-1.2	Q1537G	Neutral	0.118
BRCA1	P38398-1.2	Q1537H	Neutral	0.016
BRCA1	P38398-1.2	Q1537I	Neutral	0.051
BRCA1	P38398-1.2	Q1537K	Neutral	0.016
BRCA1	P38398-1.2	Q1537L	Neutral	0.036
BRCA1	P38398-1.2	Q1537M	Neutral	0.018
BRCA1	P38398-1.2	Q1537N	Neutral	0.022
BRCA1	P38398-1.2	Q1537P	Neutral	0.035
BRCA1	P38398-1.2	Q1537R	Neutral	0.021
BRCA1	P38398-1.2	Q1537S	Neutral	0.036
BRCA1	P38398-1.2	Q1537T	Neutral	0.033
BRCA1	P38398-1.2	Q1537V	Neutral	0.036
BRCA1	P38398-1.2	Q1537W	Neutral	0.081
BRCA1	P38398-1.2	Q1537Y	Neutral	0.037
BRCA1	P38398-1.2	Q1538A	Neutral	0.055
BRCA1	P38398-1.2	Q1538C	Neutral	0.073
BRCA1	P38398-1.2	Q1538D	Neutral	0.023
BRCA1	P38398-1.2	Q1538E	Neutral	0.008
BRCA1	P38398-1.2	Q1538F	Neutral	0.062
BRCA1	P38398-1.2	Q1538G	Neutral	0.114
BRCA1	P38398-1.2	Q1538H	Neutral	0.015
BRCA1	P38398-1.2	Q1538I	Neutral	0.049
BRCA1	P38398-1.2	Q1538K	Neutral	0.016
BRCA1	P38398-1.2	Q1538L	Neutral	0.035
BRCA1	P38398-1.2	Q1538M	Neutral	0.017
BRCA1	P38398-1.2	Q1538N	Neutral	0.021
BRCA1	P38398-1.2	Q1538P	Neutral	0.034
BRCA1	P38398-1.2	Q1538R	Neutral	0.021
BRCA1	P38398-1.2	Q1538S	Neutral	0.035
BRCA1	P38398-1.2	Q1538T	Neutral	0.032
BRCA1	P38398-1.2	Q1538V	Neutral	0.034
BRCA1	P38398-1.2	Q1538W	Neutral	0.078
BRCA1	P38398-1.2	Q1538Y	Neutral	0.036
BRCA1	P38398-1.2	L1539A	Neutral	0.201
BRCA1	P38398-1.2	L1539C	Neutral	0.143
BRCA1	P38398-1.2	L1539D	Neutral	0.301
BRCA1	P38398-1.2	L1539E	Neutral	0.168
BRCA1	P38398-1.2	L1539F	Neutral	0.061
BRCA1	P38398-1.2	L1539G	Pathogenic	0.532
BRCA1	P38398-1.2	L1539H	Neutral	0.143
BRCA1	P38398-1.2	L1539I	Neutral	0.024
BRCA1	P38398-1.2	L1539K	Neutral	0.113
BRCA1	P38398-1.2	L1539M	Neutral	0.024
BRCA1	P38398-1.2	L1539N	Neutral	0.212
BRCA1	P38398-1.2	L1539P	Neutral	0.24
BRCA1	P38398-1.2	L1539Q	Neutral	0.112
BRCA1	P38398-1.2	L1539R	Neutral	0.145
BRCA1	P38398-1.2	L1539S	Neutral	0.24
BRCA1	P38398-1.2	L1539T	Neutral	0.124
BRCA1	P38398-1.2	L1539V	Neutral	0.051
BRCA1	P38398-1.2	L1539W	Neutral	0.198
BRCA1	P38398-1.2	L1539Y	Neutral	0.095
BRCA1	P38398-1.2	E1540A	Neutral	0.003
BRCA1	P38398-1.2	E1540C	Neutral	0.006
BRCA1	P38398-1.2	E1540D	Neutral	0.001
BRCA1	P38398-1.2	E1540F	Neutral	0.004
BRCA1	P38398-1.2	E1540G	Neutral	0.006
BRCA1	P38398-1.2	E1540H	Neutral	0.001
BRCA1	P38398-1.2	E1540I	Neutral	0.003
BRCA1	P38398-1.2	E1540K	Neutral	0.001
BRCA1	P38398-1.2	E1540L	Neutral	0.003
BRCA1	P38398-1.2	E1540M	Neutral	0.002
BRCA1	P38398-1.2	E1540N	Neutral	0.001
BRCA1	P38398-1.2	E1540P	Neutral	0.002
BRCA1	P38398-1.2	E1540Q	Neutral	0.0
BRCA1	P38398-1.2	E1540R	Neutral	0.002
BRCA1	P38398-1.2	E1540S	Neutral	0.002
BRCA1	P38398-1.2	E1540T	Neutral	0.002
BRCA1	P38398-1.2	E1540V	Neutral	0.002
BRCA1	P38398-1.2	E1540W	Neutral	0.008
BRCA1	P38398-1.2	E1540Y	Neutral	0.003
BRCA1	P38398-1.2	E1541A	Neutral	0.009
BRCA1	P38398-1.2	E1541C	Neutral	0.018
BRCA1	P38398-1.2	E1541D	Neutral	0.002
BRCA1	P38398-1.2	E1541F	Neutral	0.013
BRCA1	P38398-1.2	E1541G	Neutral	0.02
BRCA1	P38398-1.2	E1541H	Neutral	0.003
BRCA1	P38398-1.2	E1541I	Neutral	0.01
BRCA1	P38398-1.2	E1541K	Neutral	0.003
BRCA1	P38398-1.2	E1541L	Neutral	0.01
BRCA1	P38398-1.2	E1541M	Neutral	0.007
BRCA1	P38398-1.2	E1541N	Neutral	0.003
BRCA1	P38398-1.2	E1541P	Neutral	0.006
BRCA1	P38398-1.2	E1541Q	Neutral	0.001
BRCA1	P38398-1.2	E1541R	Neutral	0.006
BRCA1	P38398-1.2	E1541S	Neutral	0.006
BRCA1	P38398-1.2	E1541T	Neutral	0.005
BRCA1	P38398-1.2	E1541V	Neutral	0.006
BRCA1	P38398-1.2	E1541W	Neutral	0.024
BRCA1	P38398-1.2	E1541Y	Neutral	0.011
BRCA1	P38398-1.2	S1542A	Neutral	0.015
BRCA1	P38398-1.2	S1542C	Neutral	0.035
BRCA1	P38398-1.2	S1542D	Neutral	0.027
BRCA1	P38398-1.2	S1542E	Neutral	0.04
BRCA1	P38398-1.2	S1542F	Neutral	0.132
BRCA1	P38398-1.2	S1542G	Neutral	0.032
BRCA1	P38398-1.2	S1542H	Neutral	0.069
BRCA1	P38398-1.2	S1542I	Neutral	0.106
BRCA1	P38398-1.2	S1542K	Neutral	0.069
BRCA1	P38398-1.2	S1542L	Neutral	0.106
BRCA1	P38398-1.2	S1542M	Neutral	0.077
BRCA1	P38398-1.2	S1542N	Neutral	0.021
BRCA1	P38398-1.2	S1542P	Neutral	0.038
BRCA1	P38398-1.2	S1542Q	Neutral	0.045
BRCA1	P38398-1.2	S1542R	Neutral	0.125
BRCA1	P38398-1.2	S1542T	Neutral	0.02
BRCA1	P38398-1.2	S1542V	Neutral	0.073
BRCA1	P38398-1.2	S1542W	Neutral	0.287
BRCA1	P38398-1.2	S1542Y	Neutral	0.15
BRCA1	P38398-1.2	G1543A	Neutral	0.025
BRCA1	P38398-1.2	G1543C	Neutral	0.103
BRCA1	P38398-1.2	G1543D	Neutral	0.058
BRCA1	P38398-1.2	G1543E	Neutral	0.118
BRCA1	P38398-1.2	G1543F	Neutral	0.251
BRCA1	P38398-1.2	G1543H	Neutral	0.141
BRCA1	P38398-1.2	G1543I	Neutral	0.274
BRCA1	P38398-1.2	G1543K	Neutral	0.191
BRCA1	P38398-1.2	G1543L	Neutral	0.274
BRCA1	P38398-1.2	G1543M	Neutral	0.21
BRCA1	P38398-1.2	G1543N	Neutral	0.046
BRCA1	P38398-1.2	G1543P	Neutral	0.08
BRCA1	P38398-1.2	G1543Q	Neutral	0.131
BRCA1	P38398-1.2	G1543R	Neutral	0.24
BRCA1	P38398-1.2	G1543S	Neutral	0.029
BRCA1	P38398-1.2	G1543T	Neutral	0.086
BRCA1	P38398-1.2	G1543V	Neutral	0.148
BRCA1	P38398-1.2	G1543W	Neutral	0.301
BRCA1	P38398-1.2	G1543Y	Neutral	0.28
BRCA1	P38398-1.2	P1544A	Neutral	0.019
BRCA1	P38398-1.2	P1544C	Neutral	0.026
BRCA1	P38398-1.2	P1544D	Neutral	0.012
BRCA1	P38398-1.2	P1544E	Neutral	0.018
BRCA1	P38398-1.2	P1544F	Neutral	0.087
BRCA1	P38398-1.2	P1544G	Neutral	0.041
BRCA1	P38398-1.2	P1544H	Neutral	0.031
BRCA1	P38398-1.2	P1544I	Neutral	0.049
BRCA1	P38398-1.2	P1544K	Neutral	0.031
BRCA1	P38398-1.2	P1544L	Neutral	0.049
BRCA1	P38398-1.2	P1544M	Neutral	0.035
BRCA1	P38398-1.2	P1544N	Neutral	0.019
BRCA1	P38398-1.2	P1544Q	Neutral	0.02
BRCA1	P38398-1.2	P1544R	Neutral	0.057
BRCA1	P38398-1.2	P1544S	Neutral	0.017
BRCA1	P38398-1.2	P1544T	Neutral	0.013
BRCA1	P38398-1.2	P1544V	Neutral	0.023
BRCA1	P38398-1.2	P1544W	Neutral	0.149
BRCA1	P38398-1.2	P1544Y	Neutral	0.071
BRCA1	P38398-1.2	H1545A	Neutral	0.082
BRCA1	P38398-1.2	H1545C	Neutral	0.076
BRCA1	P38398-1.2	H1545D	Neutral	0.034
BRCA1	P38398-1.2	H1545E	Neutral	0.016
BRCA1	P38398-1.2	H1545F	Neutral	0.027
BRCA1	P38398-1.2	H1545G	Neutral	0.119
BRCA1	P38398-1.2	H1545I	Neutral	0.044
BRCA1	P38398-1.2	H1545K	Neutral	0.028
BRCA1	P38398-1.2	H1545L	Neutral	0.044
BRCA1	P38398-1.2	H1545M	Neutral	0.031
BRCA1	P38398-1.2	H1545N	Neutral	0.015
BRCA1	P38398-1.2	H1545P	Neutral	0.05
BRCA1	P38398-1.2	H1545Q	Neutral	0.015
BRCA1	P38398-1.2	H1545R	Neutral	0.026
BRCA1	P38398-1.2	H1545S	Neutral	0.051
BRCA1	P38398-1.2	H1545T	Neutral	0.048
BRCA1	P38398-1.2	H1545V	Neutral	0.051
BRCA1	P38398-1.2	H1545W	Neutral	0.07
BRCA1	P38398-1.2	H1545Y	Neutral	0.011
BRCA1	P38398-1.2	D1546A	Neutral	0.021
BRCA1	P38398-1.2	D1546C	Neutral	0.019
BRCA1	P38398-1.2	D1546E	Neutral	0.004
BRCA1	P38398-1.2	D1546F	Neutral	0.044
BRCA1	P38398-1.2	D1546G	Neutral	0.022
BRCA1	P38398-1.2	D1546H	Neutral	0.016
BRCA1	P38398-1.2	D1546I	Neutral	0.035
BRCA1	P38398-1.2	D1546K	Neutral	0.023
BRCA1	P38398-1.2	D1546L	Neutral	0.05
BRCA1	P38398-1.2	D1546M	Neutral	0.035
BRCA1	P38398-1.2	D1546N	Neutral	0.005
BRCA1	P38398-1.2	D1546P	Neutral	0.009
BRCA1	P38398-1.2	D1546Q	Neutral	0.01
BRCA1	P38398-1.2	D1546R	Neutral	0.043
BRCA1	P38398-1.2	D1546S	Neutral	0.009
BRCA1	P38398-1.2	D1546T	Neutral	0.009
BRCA1	P38398-1.2	D1546V	Neutral	0.023
BRCA1	P38398-1.2	D1546W	Neutral	0.109
BRCA1	P38398-1.2	D1546Y	Neutral	0.051
BRCA1	P38398-1.2	L1547A	Neutral	0.047
BRCA1	P38398-1.2	L1547C	Neutral	0.032
BRCA1	P38398-1.2	L1547D	Neutral	0.078
BRCA1	P38398-1.2	L1547E	Neutral	0.038
BRCA1	P38398-1.2	L1547F	Neutral	0.013
BRCA1	P38398-1.2	L1547G	Neutral	0.183
BRCA1	P38398-1.2	L1547H	Neutral	0.032
BRCA1	P38398-1.2	L1547I	Neutral	0.005
BRCA1	P38398-1.2	L1547K	Neutral	0.024
BRCA1	P38398-1.2	L1547M	Neutral	0.005
BRCA1	P38398-1.2	L1547N	Neutral	0.05
BRCA1	P38398-1.2	L1547P	Neutral	0.058
BRCA1	P38398-1.2	L1547Q	Neutral	0.024
BRCA1	P38398-1.2	L1547R	Neutral	0.032
BRCA1	P38398-1.2	L1547S	Neutral	0.058
BRCA1	P38398-1.2	L1547T	Neutral	0.027
BRCA1	P38398-1.2	L1547V	Neutral	0.01
BRCA1	P38398-1.2	L1547W	Neutral	0.046
BRCA1	P38398-1.2	L1547Y	Neutral	0.02
BRCA1	P38398-1.2	T1548A	Neutral	0.008
BRCA1	P38398-1.2	T1548C	Neutral	0.007
BRCA1	P38398-1.2	T1548D	Neutral	0.007
BRCA1	P38398-1.2	T1548E	Neutral	0.009
BRCA1	P38398-1.2	T1548F	Neutral	0.022
BRCA1	P38398-1.2	T1548G	Neutral	0.024
BRCA1	P38398-1.2	T1548H	Neutral	0.016
BRCA1	P38398-1.2	T1548I	Neutral	0.012
BRCA1	P38398-1.2	T1548K	Neutral	0.016
BRCA1	P38398-1.2	T1548L	Neutral	0.012
BRCA1	P38398-1.2	T1548M	Neutral	0.012
BRCA1	P38398-1.2	T1548N	Neutral	0.005
BRCA1	P38398-1.2	T1548P	Neutral	0.007
BRCA1	P38398-1.2	T1548Q	Neutral	0.01
BRCA1	P38398-1.2	T1548R	Neutral	0.021
BRCA1	P38398-1.2	T1548S	Neutral	0.005
BRCA1	P38398-1.2	T1548V	Neutral	0.006
BRCA1	P38398-1.2	T1548W	Neutral	0.04
BRCA1	P38398-1.2	T1548Y	Neutral	0.026
BRCA1	P38398-1.2	E1549A	Neutral	0.031
BRCA1	P38398-1.2	E1549C	Neutral	0.058
BRCA1	P38398-1.2	E1549D	Neutral	0.006
BRCA1	P38398-1.2	E1549F	Neutral	0.043
BRCA1	P38398-1.2	E1549G	Neutral	0.066
BRCA1	P38398-1.2	E1549H	Neutral	0.011
BRCA1	P38398-1.2	E1549I	Neutral	0.034
BRCA1	P38398-1.2	E1549K	Neutral	0.011
BRCA1	P38398-1.2	E1549L	Neutral	0.034
BRCA1	P38398-1.2	E1549M	Neutral	0.024
BRCA1	P38398-1.2	E1549N	Neutral	0.012
BRCA1	P38398-1.2	E1549P	Neutral	0.019
BRCA1	P38398-1.2	E1549Q	Neutral	0.005
BRCA1	P38398-1.2	E1549R	Neutral	0.021
BRCA1	P38398-1.2	E1549S	Neutral	0.019
BRCA1	P38398-1.2	E1549T	Neutral	0.018
BRCA1	P38398-1.2	E1549V	Neutral	0.019
BRCA1	P38398-1.2	E1549W	Neutral	0.077
BRCA1	P38398-1.2	E1549Y	Neutral	0.035
BRCA1	P38398-1.2	T1550A	Neutral	0.003
BRCA1	P38398-1.2	T1550C	Neutral	0.003
BRCA1	P38398-1.2	T1550D	Neutral	0.003
BRCA1	P38398-1.2	T1550E	Neutral	0.004
BRCA1	P38398-1.2	T1550F	Neutral	0.009
BRCA1	P38398-1.2	T1550G	Neutral	0.01
BRCA1	P38398-1.2	T1550H	Neutral	0.007
BRCA1	P38398-1.2	T1550I	Neutral	0.005
BRCA1	P38398-1.2	T1550K	Neutral	0.007
BRCA1	P38398-1.2	T1550L	Neutral	0.005
BRCA1	P38398-1.2	T1550M	Neutral	0.005
BRCA1	P38398-1.2	T1550N	Neutral	0.002
BRCA1	P38398-1.2	T1550P	Neutral	0.003
BRCA1	P38398-1.2	T1550Q	Neutral	0.004
BRCA1	P38398-1.2	T1550R	Neutral	0.009
BRCA1	P38398-1.2	T1550S	Neutral	0.002
BRCA1	P38398-1.2	T1550V	Neutral	0.002
BRCA1	P38398-1.2	T1550W	Neutral	0.017
BRCA1	P38398-1.2	T1550Y	Neutral	0.011
BRCA1	P38398-1.2	S1551A	Neutral	0.01
BRCA1	P38398-1.2	S1551C	Neutral	0.023
BRCA1	P38398-1.2	S1551D	Neutral	0.018
BRCA1	P38398-1.2	S1551E	Neutral	0.027
BRCA1	P38398-1.2	S1551F	Neutral	0.091
BRCA1	P38398-1.2	S1551G	Neutral	0.021
BRCA1	P38398-1.2	S1551H	Neutral	0.047
BRCA1	P38398-1.2	S1551I	Neutral	0.073
BRCA1	P38398-1.2	S1551K	Neutral	0.047
BRCA1	P38398-1.2	S1551L	Neutral	0.073
BRCA1	P38398-1.2	S1551M	Neutral	0.052
BRCA1	P38398-1.2	S1551N	Neutral	0.014
BRCA1	P38398-1.2	S1551P	Neutral	0.025
BRCA1	P38398-1.2	S1551Q	Neutral	0.03
BRCA1	P38398-1.2	S1551R	Neutral	0.086
BRCA1	P38398-1.2	S1551T	Neutral	0.013
BRCA1	P38398-1.2	S1551V	Neutral	0.049
BRCA1	P38398-1.2	S1551W	Neutral	0.21
BRCA1	P38398-1.2	S1551Y	Neutral	0.104
BRCA1	P38398-1.2	Y1552A	Neutral	0.356
BRCA1	P38398-1.2	Y1552C	Neutral	0.269
BRCA1	P38398-1.2	Y1552D	Neutral	0.314
BRCA1	P38398-1.2	Y1552E	Neutral	0.176
BRCA1	P38398-1.2	Y1552F	Neutral	0.019
BRCA1	P38398-1.2	Y1552G	Pathogenic	0.547
BRCA1	P38398-1.2	Y1552H	Neutral	0.04
BRCA1	P38398-1.2	Y1552I	Neutral	0.097
BRCA1	P38398-1.2	Y1552K	Neutral	0.106
BRCA1	P38398-1.2	Y1552L	Neutral	0.098
BRCA1	P38398-1.2	Y1552M	Neutral	0.098
BRCA1	P38398-1.2	Y1552N	Neutral	0.222
BRCA1	P38398-1.2	Y1552P	Neutral	0.325
BRCA1	P38398-1.2	Y1552Q	Neutral	0.118
BRCA1	P38398-1.2	Y1552R	Neutral	0.109
BRCA1	P38398-1.2	Y1552S	Neutral	0.325
BRCA1	P38398-1.2	Y1552T	Neutral	0.237
BRCA1	P38398-1.2	Y1552V	Neutral	0.143
BRCA1	P38398-1.2	Y1552W	Neutral	0.039
BRCA1	P38398-1.2	L1553A	Pathogenic	0.541
BRCA1	P38398-1.2	L1553C	Neutral	0.439
BRCA1	P38398-1.2	L1553D	Pathogenic	0.669
BRCA1	P38398-1.2	L1553E	Neutral	0.486
BRCA1	P38398-1.2	L1553F	Neutral	0.232
BRCA1	P38398-1.2	L1553G	Pathogenic	0.842
BRCA1	P38398-1.2	L1553H	Neutral	0.44
BRCA1	P38398-1.2	L1553I	Neutral	0.103
BRCA1	P38398-1.2	L1553K	Neutral	0.373
BRCA1	P38398-1.2	L1553M	Neutral	0.102
BRCA1	P38398-1.2	L1553N	Pathogenic	0.558
BRCA1	P38398-1.2	L1553P	Pathogenic	0.596
BRCA1	P38398-1.2	L1553Q	Neutral	0.372
BRCA1	P38398-1.2	L1553R	Neutral	0.443
BRCA1	P38398-1.2	L1553S	Pathogenic	0.596
BRCA1	P38398-1.2	L1553T	Neutral	0.398
BRCA1	P38398-1.2	L1553V	Neutral	0.2
BRCA1	P38398-1.2	L1553W	Pathogenic	0.536
BRCA1	P38398-1.2	L1553Y	Neutral	0.329
BRCA1	P38398-1.2	P1554A	Pathogenic	0.532
BRCA1	P38398-1.2	P1554C	Pathogenic	0.608
BRCA1	P38398-1.2	P1554D	Neutral	0.406
BRCA1	P38398-1.2	P1554E	Pathogenic	0.506
BRCA1	P38398-1.2	P1554F	Pathogenic	0.845
BRCA1	P38398-1.2	P1554G	Pathogenic	0.713
BRCA1	P38398-1.2	P1554H	Pathogenic	0.646
BRCA1	P38398-1.2	P1554I	Pathogenic	0.748
BRCA1	P38398-1.2	P1554K	Pathogenic	0.644
BRCA1	P38398-1.2	P1554L	Pathogenic	0.749
BRCA1	P38398-1.2	P1554M	Pathogenic	0.676
BRCA1	P38398-1.2	P1554N	Pathogenic	0.525
BRCA1	P38398-1.2	P1554Q	Pathogenic	0.535
BRCA1	P38398-1.2	P1554R	Pathogenic	0.777
BRCA1	P38398-1.2	P1554S	Neutral	0.497
BRCA1	P38398-1.2	P1554T	Neutral	0.422
BRCA1	P38398-1.2	P1554V	Pathogenic	0.578
BRCA1	P38398-1.2	P1554W	Pathogenic	0.91
BRCA1	P38398-1.2	P1554Y	Pathogenic	0.815
BRCA1	P38398-1.2	R1555A	Neutral	0.424
BRCA1	P38398-1.2	R1555C	Neutral	0.497
BRCA1	P38398-1.2	R1555D	Neutral	0.389
BRCA1	P38398-1.2	R1555E	Neutral	0.17
BRCA1	P38398-1.2	R1555F	Neutral	0.247
BRCA1	P38398-1.2	R1555G	Pathogenic	0.619
BRCA1	P38398-1.2	R1555H	Neutral	0.142
BRCA1	P38398-1.2	R1555I	Neutral	0.295
BRCA1	P38398-1.2	R1555K	Neutral	0.053
BRCA1	P38398-1.2	R1555L	Neutral	0.225
BRCA1	P38398-1.2	R1555M	Neutral	0.17
BRCA1	P38398-1.2	R1555N	Neutral	0.215
BRCA1	P38398-1.2	R1555P	Neutral	0.387
BRCA1	P38398-1.2	R1555Q	Neutral	0.112
BRCA1	P38398-1.2	R1555S	Neutral	0.394
BRCA1	P38398-1.2	R1555T	Neutral	0.293
BRCA1	P38398-1.2	R1555V	Neutral	0.392
BRCA1	P38398-1.2	R1555W	Neutral	0.253
BRCA1	P38398-1.2	R1555Y	Neutral	0.168
BRCA1	P38398-1.2	Q1556A	Neutral	0.32
BRCA1	P38398-1.2	Q1556C	Neutral	0.387
BRCA1	P38398-1.2	Q1556D	Neutral	0.161
BRCA1	P38398-1.2	Q1556E	Neutral	0.059
BRCA1	P38398-1.2	Q1556F	Neutral	0.348
BRCA1	P38398-1.2	Q1556G	Pathogenic	0.51
BRCA1	P38398-1.2	Q1556H	Neutral	0.112
BRCA1	P38398-1.2	Q1556I	Neutral	0.294
BRCA1	P38398-1.2	Q1556K	Neutral	0.113
BRCA1	P38398-1.2	Q1556L	Neutral	0.225
BRCA1	P38398-1.2	Q1556M	Neutral	0.124
BRCA1	P38398-1.2	Q1556N	Neutral	0.147
BRCA1	P38398-1.2	Q1556P	Neutral	0.219
BRCA1	P38398-1.2	Q1556R	Neutral	0.145
BRCA1	P38398-1.2	Q1556S	Neutral	0.224
BRCA1	P38398-1.2	Q1556T	Neutral	0.209
BRCA1	P38398-1.2	Q1556V	Neutral	0.223
BRCA1	P38398-1.2	Q1556W	Neutral	0.406
BRCA1	P38398-1.2	Q1556Y	Neutral	0.23
BRCA1	P38398-1.2	D1557A	Neutral	0.102
BRCA1	P38398-1.2	D1557C	Neutral	0.096
BRCA1	P38398-1.2	D1557E	Neutral	0.023
BRCA1	P38398-1.2	D1557F	Neutral	0.199
BRCA1	P38398-1.2	D1557G	Neutral	0.108
BRCA1	P38398-1.2	D1557H	Neutral	0.078
BRCA1	P38398-1.2	D1557I	Neutral	0.162
BRCA1	P38398-1.2	D1557K	Neutral	0.111
BRCA1	P38398-1.2	D1557L	Neutral	0.219
BRCA1	P38398-1.2	D1557M	Neutral	0.164
BRCA1	P38398-1.2	D1557N	Neutral	0.025
BRCA1	P38398-1.2	D1557P	Neutral	0.045
BRCA1	P38398-1.2	D1557Q	Neutral	0.051
BRCA1	P38398-1.2	D1557R	Neutral	0.194
BRCA1	P38398-1.2	D1557S	Neutral	0.046
BRCA1	P38398-1.2	D1557T	Neutral	0.046
BRCA1	P38398-1.2	D1557V	Neutral	0.114
BRCA1	P38398-1.2	D1557W	Neutral	0.397
BRCA1	P38398-1.2	D1557Y	Neutral	0.223
BRCA1	P38398-1.2	L1558A	Neutral	0.165
BRCA1	P38398-1.2	L1558C	Neutral	0.116
BRCA1	P38398-1.2	L1558D	Neutral	0.254
BRCA1	P38398-1.2	L1558E	Neutral	0.137
BRCA1	P38398-1.2	L1558F	Neutral	0.048
BRCA1	P38398-1.2	L1558G	Neutral	0.473
BRCA1	P38398-1.2	L1558H	Neutral	0.117
BRCA1	P38398-1.2	L1558I	Neutral	0.019
BRCA1	P38398-1.2	L1558K	Neutral	0.091
BRCA1	P38398-1.2	L1558M	Neutral	0.019
BRCA1	P38398-1.2	L1558N	Neutral	0.175
BRCA1	P38398-1.2	L1558P	Neutral	0.199
BRCA1	P38398-1.2	L1558Q	Neutral	0.09
BRCA1	P38398-1.2	L1558R	Neutral	0.118
BRCA1	P38398-1.2	L1558S	Neutral	0.199
BRCA1	P38398-1.2	L1558T	Neutral	0.1
BRCA1	P38398-1.2	L1558V	Neutral	0.04
BRCA1	P38398-1.2	L1558W	Neutral	0.163
BRCA1	P38398-1.2	L1558Y	Neutral	0.076
BRCA1	P38398-1.2	E1559A	Neutral	0.301
BRCA1	P38398-1.2	E1559C	Neutral	0.453
BRCA1	P38398-1.2	E1559D	Neutral	0.079
BRCA1	P38398-1.2	E1559F	Neutral	0.378
BRCA1	P38398-1.2	E1559G	Neutral	0.487
BRCA1	P38398-1.2	E1559H	Neutral	0.126
BRCA1	P38398-1.2	E1559I	Neutral	0.322
BRCA1	P38398-1.2	E1559K	Neutral	0.128
BRCA1	P38398-1.2	E1559L	Neutral	0.322
BRCA1	P38398-1.2	E1559M	Neutral	0.25
BRCA1	P38398-1.2	E1559N	Neutral	0.138
BRCA1	P38398-1.2	E1559P	Neutral	0.204
BRCA1	P38398-1.2	E1559Q	Neutral	0.06
BRCA1	P38398-1.2	E1559R	Neutral	0.22
BRCA1	P38398-1.2	E1559S	Neutral	0.208
BRCA1	P38398-1.2	E1559T	Neutral	0.195
BRCA1	P38398-1.2	E1559V	Neutral	0.207
BRCA1	P38398-1.2	E1559W	Pathogenic	0.528
BRCA1	P38398-1.2	E1559Y	Neutral	0.329
BRCA1	P38398-1.2	G1560A	Neutral	0.123
BRCA1	P38398-1.2	G1560C	Neutral	0.387
BRCA1	P38398-1.2	G1560D	Neutral	0.255
BRCA1	P38398-1.2	G1560E	Neutral	0.424
BRCA1	P38398-1.2	G1560F	Pathogenic	0.649
BRCA1	P38398-1.2	G1560H	Neutral	0.476
BRCA1	P38398-1.2	G1560I	Pathogenic	0.675
BRCA1	P38398-1.2	G1560K	Pathogenic	0.566
BRCA1	P38398-1.2	G1560L	Pathogenic	0.676
BRCA1	P38398-1.2	G1560M	Pathogenic	0.594
BRCA1	P38398-1.2	G1560N	Neutral	0.21
BRCA1	P38398-1.2	G1560P	Neutral	0.325
BRCA1	P38398-1.2	G1560Q	Neutral	0.453
BRCA1	P38398-1.2	G1560R	Pathogenic	0.635
BRCA1	P38398-1.2	G1560S	Neutral	0.139
BRCA1	P38398-1.2	G1560T	Neutral	0.342
BRCA1	P38398-1.2	G1560V	Neutral	0.49
BRCA1	P38398-1.2	G1560W	Pathogenic	0.703
BRCA1	P38398-1.2	G1560Y	Pathogenic	0.682
BRCA1	P38398-1.2	T1561A	Neutral	0.211
BRCA1	P38398-1.2	T1561C	Neutral	0.199
BRCA1	P38398-1.2	T1561D	Neutral	0.181
BRCA1	P38398-1.2	T1561E	Neutral	0.232
BRCA1	P38398-1.2	T1561F	Neutral	0.434
BRCA1	P38398-1.2	T1561G	Neutral	0.456
BRCA1	P38398-1.2	T1561H	Neutral	0.35
BRCA1	P38398-1.2	T1561I	Neutral	0.294
BRCA1	P38398-1.2	T1561K	Neutral	0.349
BRCA1	P38398-1.2	T1561L	Neutral	0.295
BRCA1	P38398-1.2	T1561M	Neutral	0.296
BRCA1	P38398-1.2	T1561N	Neutral	0.136
BRCA1	P38398-1.2	T1561P	Neutral	0.186
BRCA1	P38398-1.2	T1561Q	Neutral	0.254
BRCA1	P38398-1.2	T1561R	Neutral	0.417
BRCA1	P38398-1.2	T1561S	Neutral	0.139
BRCA1	P38398-1.2	T1561V	Neutral	0.161
BRCA1	P38398-1.2	T1561W	Pathogenic	0.586
BRCA1	P38398-1.2	T1561Y	Neutral	0.471
BRCA1	P38398-1.2	P1562A	Neutral	0.228
BRCA1	P38398-1.2	P1562C	Neutral	0.287
BRCA1	P38398-1.2	P1562D	Neutral	0.151
BRCA1	P38398-1.2	P1562E	Neutral	0.21
BRCA1	P38398-1.2	P1562F	Pathogenic	0.587
BRCA1	P38398-1.2	P1562G	Neutral	0.392
BRCA1	P38398-1.2	P1562H	Neutral	0.322
BRCA1	P38398-1.2	P1562I	Neutral	0.436
BRCA1	P38398-1.2	P1562K	Neutral	0.32
BRCA1	P38398-1.2	P1562L	Neutral	0.436
BRCA1	P38398-1.2	P1562M	Neutral	0.352
BRCA1	P38398-1.2	P1562N	Neutral	0.223
BRCA1	P38398-1.2	P1562Q	Neutral	0.23
BRCA1	P38398-1.2	P1562R	Neutral	0.475
BRCA1	P38398-1.2	P1562S	Neutral	0.205
BRCA1	P38398-1.2	P1562T	Neutral	0.159
BRCA1	P38398-1.2	P1562V	Neutral	0.262
BRCA1	P38398-1.2	P1562W	Pathogenic	0.724
BRCA1	P38398-1.2	P1562Y	Pathogenic	0.534
BRCA1	P38398-1.2	Y1563A	Pathogenic	0.541
BRCA1	P38398-1.2	Y1563C	Neutral	0.438
BRCA1	P38398-1.2	Y1563D	Neutral	0.493
BRCA1	P38398-1.2	Y1563E	Neutral	0.312
BRCA1	P38398-1.2	Y1563F	Neutral	0.04
BRCA1	P38398-1.2	Y1563G	Pathogenic	0.72
BRCA1	P38398-1.2	Y1563H	Neutral	0.081
BRCA1	P38398-1.2	Y1563I	Neutral	0.187
BRCA1	P38398-1.2	Y1563K	Neutral	0.202
BRCA1	P38398-1.2	Y1563L	Neutral	0.187
BRCA1	P38398-1.2	Y1563M	Neutral	0.188
BRCA1	P38398-1.2	Y1563N	Neutral	0.378
BRCA1	P38398-1.2	Y1563P	Pathogenic	0.506
BRCA1	P38398-1.2	Y1563Q	Neutral	0.222
BRCA1	P38398-1.2	Y1563R	Neutral	0.206
BRCA1	P38398-1.2	Y1563S	Pathogenic	0.506
BRCA1	P38398-1.2	Y1563T	Neutral	0.397
BRCA1	P38398-1.2	Y1563V	Neutral	0.262
BRCA1	P38398-1.2	Y1563W	Neutral	0.079
BRCA1	P38398-1.2	L1564A	Neutral	0.481
BRCA1	P38398-1.2	L1564C	Neutral	0.381
BRCA1	P38398-1.2	L1564D	Pathogenic	0.614
BRCA1	P38398-1.2	L1564E	Neutral	0.426
BRCA1	P38398-1.2	L1564F	Neutral	0.192
BRCA1	P38398-1.2	L1564G	Pathogenic	0.807
BRCA1	P38398-1.2	L1564H	Neutral	0.381
BRCA1	P38398-1.2	L1564I	Neutral	0.082
BRCA1	P38398-1.2	L1564K	Neutral	0.319
BRCA1	P38398-1.2	L1564M	Neutral	0.082
BRCA1	P38398-1.2	L1564N	Neutral	0.498
BRCA1	P38398-1.2	L1564P	Pathogenic	0.537
BRCA1	P38398-1.2	L1564Q	Neutral	0.317
BRCA1	P38398-1.2	L1564R	Neutral	0.385
BRCA1	P38398-1.2	L1564S	Pathogenic	0.537
BRCA1	P38398-1.2	L1564T	Neutral	0.342
BRCA1	P38398-1.2	L1564V	Neutral	0.164
BRCA1	P38398-1.2	L1564W	Neutral	0.476
BRCA1	P38398-1.2	L1564Y	Neutral	0.279
BRCA1	P38398-1.2	E1565A	Neutral	0.137
BRCA1	P38398-1.2	E1565C	Neutral	0.234
BRCA1	P38398-1.2	E1565D	Neutral	0.031
BRCA1	P38398-1.2	E1565F	Neutral	0.183
BRCA1	P38398-1.2	E1565G	Neutral	0.259
BRCA1	P38398-1.2	E1565H	Neutral	0.05
BRCA1	P38398-1.2	E1565I	Neutral	0.149
BRCA1	P38398-1.2	E1565K	Neutral	0.052
BRCA1	P38398-1.2	E1565L	Neutral	0.149
BRCA1	P38398-1.2	E1565M	Neutral	0.11
BRCA1	P38398-1.2	E1565N	Neutral	0.056
BRCA1	P38398-1.2	E1565P	Neutral	0.086
BRCA1	P38398-1.2	E1565Q	Neutral	0.023
BRCA1	P38398-1.2	E1565R	Neutral	0.094
BRCA1	P38398-1.2	E1565S	Neutral	0.089
BRCA1	P38398-1.2	E1565T	Neutral	0.082
BRCA1	P38398-1.2	E1565V	Neutral	0.088
BRCA1	P38398-1.2	E1565W	Neutral	0.292
BRCA1	P38398-1.2	E1565Y	Neutral	0.153
BRCA1	P38398-1.2	S1566A	Neutral	0.321
BRCA1	P38398-1.2	S1566C	Pathogenic	0.53
BRCA1	P38398-1.2	S1566D	Neutral	0.468
BRCA1	P38398-1.2	S1566E	Pathogenic	0.568
BRCA1	P38398-1.2	S1566F	Pathogenic	0.826
BRCA1	P38398-1.2	S1566G	Pathogenic	0.51
BRCA1	P38398-1.2	S1566H	Pathogenic	0.7
BRCA1	P38398-1.2	S1566I	Pathogenic	0.788
BRCA1	P38398-1.2	S1566K	Pathogenic	0.7
BRCA1	P38398-1.2	S1566L	Pathogenic	0.788
BRCA1	P38398-1.2	S1566M	Pathogenic	0.723
BRCA1	P38398-1.2	S1566N	Neutral	0.407
BRCA1	P38398-1.2	S1566P	Pathogenic	0.553
BRCA1	P38398-1.2	S1566Q	Pathogenic	0.597
BRCA1	P38398-1.2	S1566R	Pathogenic	0.817
BRCA1	P38398-1.2	S1566T	Neutral	0.392
BRCA1	P38398-1.2	S1566V	Pathogenic	0.711
BRCA1	P38398-1.2	S1566W	Pathogenic	0.926
BRCA1	P38398-1.2	S1566Y	Pathogenic	0.846
BRCA1	P38398-1.2	G1567A	Pathogenic	0.617
BRCA1	P38398-1.2	G1567C	Pathogenic	0.878
BRCA1	P38398-1.2	G1567D	Pathogenic	0.796
BRCA1	P38398-1.2	G1567E	Pathogenic	0.894
BRCA1	P38398-1.2	G1567F	Pathogenic	0.955
BRCA1	P38398-1.2	G1567H	Pathogenic	0.912
BRCA1	P38398-1.2	G1567I	Pathogenic	0.96
BRCA1	P38398-1.2	G1567K	Pathogenic	0.937
BRCA1	P38398-1.2	G1567L	Pathogenic	0.96
BRCA1	P38398-1.2	G1567M	Pathogenic	0.943
BRCA1	P38398-1.2	G1567N	Pathogenic	0.753
BRCA1	P38398-1.2	G1567P	Pathogenic	0.846
BRCA1	P38398-1.2	G1567Q	Pathogenic	0.905
BRCA1	P38398-1.2	G1567R	Pathogenic	0.952
BRCA1	P38398-1.2	G1567S	Pathogenic	0.649
BRCA1	P38398-1.2	G1567T	Pathogenic	0.856
BRCA1	P38398-1.2	G1567V	Pathogenic	0.916
BRCA1	P38398-1.2	G1567W	Pathogenic	0.964
BRCA1	P38398-1.2	G1567Y	Pathogenic	0.961
BRCA1	P38398-1.2	I1568A	Neutral	0.174
BRCA1	P38398-1.2	I1568C	Neutral	0.123
BRCA1	P38398-1.2	I1568D	Neutral	0.201
BRCA1	P38398-1.2	I1568E	Neutral	0.144
BRCA1	P38398-1.2	I1568F	Neutral	0.051
BRCA1	P38398-1.2	I1568G	Neutral	0.488
BRCA1	P38398-1.2	I1568H	Neutral	0.123
BRCA1	P38398-1.2	I1568K	Neutral	0.133
BRCA1	P38398-1.2	I1568L	Neutral	0.02
BRCA1	P38398-1.2	I1568M	Neutral	0.028
BRCA1	P38398-1.2	I1568N	Neutral	0.184
BRCA1	P38398-1.2	I1568P	Neutral	0.209
BRCA1	P38398-1.2	I1568Q	Neutral	0.132
BRCA1	P38398-1.2	I1568R	Neutral	0.17
BRCA1	P38398-1.2	I1568S	Neutral	0.209
BRCA1	P38398-1.2	I1568T	Neutral	0.106
BRCA1	P38398-1.2	I1568V	Neutral	0.021
BRCA1	P38398-1.2	I1568W	Neutral	0.23
BRCA1	P38398-1.2	I1568Y	Neutral	0.081
BRCA1	P38398-1.2	S1569A	Neutral	0.039
BRCA1	P38398-1.2	S1569C	Neutral	0.088
BRCA1	P38398-1.2	S1569D	Neutral	0.07
BRCA1	P38398-1.2	S1569E	Neutral	0.102
BRCA1	P38398-1.2	S1569F	Neutral	0.29
BRCA1	P38398-1.2	S1569G	Neutral	0.082
BRCA1	P38398-1.2	S1569H	Neutral	0.167
BRCA1	P38398-1.2	S1569I	Neutral	0.242
BRCA1	P38398-1.2	S1569K	Neutral	0.167
BRCA1	P38398-1.2	S1569L	Neutral	0.242
BRCA1	P38398-1.2	S1569M	Neutral	0.183
BRCA1	P38398-1.2	S1569N	Neutral	0.056
BRCA1	P38398-1.2	S1569P	Neutral	0.096
BRCA1	P38398-1.2	S1569Q	Neutral	0.113
BRCA1	P38398-1.2	S1569R	Neutral	0.278
BRCA1	P38398-1.2	S1569T	Neutral	0.053
BRCA1	P38398-1.2	S1569V	Neutral	0.175
BRCA1	P38398-1.2	S1569W	Pathogenic	0.52
BRCA1	P38398-1.2	S1569Y	Neutral	0.321
BRCA1	P38398-1.2	L1570A	Pathogenic	0.636
BRCA1	P38398-1.2	L1570C	Pathogenic	0.537
BRCA1	P38398-1.2	L1570D	Pathogenic	0.749
BRCA1	P38398-1.2	L1570E	Pathogenic	0.582
BRCA1	P38398-1.2	L1570F	Neutral	0.309
BRCA1	P38398-1.2	L1570G	Pathogenic	0.887
BRCA1	P38398-1.2	L1570H	Pathogenic	0.537
BRCA1	P38398-1.2	L1570I	Neutral	0.145
BRCA1	P38398-1.2	L1570K	Neutral	0.468
BRCA1	P38398-1.2	L1570M	Neutral	0.144
BRCA1	P38398-1.2	L1570N	Pathogenic	0.651
BRCA1	P38398-1.2	L1570P	Pathogenic	0.686
BRCA1	P38398-1.2	L1570Q	Neutral	0.467
BRCA1	P38398-1.2	L1570R	Pathogenic	0.54
BRCA1	P38398-1.2	L1570S	Pathogenic	0.686
BRCA1	P38398-1.2	L1570T	Neutral	0.494
BRCA1	P38398-1.2	L1570V	Neutral	0.269
BRCA1	P38398-1.2	L1570W	Pathogenic	0.631
BRCA1	P38398-1.2	L1570Y	Neutral	0.421
BRCA1	P38398-1.2	F1571A	Pathogenic	0.743
BRCA1	P38398-1.2	F1571C	Pathogenic	0.657
BRCA1	P38398-1.2	F1571D	Pathogenic	0.705
BRCA1	P38398-1.2	F1571E	Pathogenic	0.616
BRCA1	P38398-1.2	F1571G	Pathogenic	0.863
BRCA1	P38398-1.2	F1571H	Neutral	0.392
BRCA1	P38398-1.2	F1571I	Neutral	0.288
BRCA1	P38398-1.2	F1571K	Neutral	0.472
BRCA1	P38398-1.2	F1571L	Neutral	0.288
BRCA1	P38398-1.2	F1571M	Neutral	0.286
BRCA1	P38398-1.2	F1571N	Pathogenic	0.682
BRCA1	P38398-1.2	F1571P	Pathogenic	0.783
BRCA1	P38398-1.2	F1571Q	Pathogenic	0.592
BRCA1	P38398-1.2	F1571R	Pathogenic	0.544
BRCA1	P38398-1.2	F1571S	Pathogenic	0.715
BRCA1	P38398-1.2	F1571T	Pathogenic	0.618
BRCA1	P38398-1.2	F1571V	Neutral	0.468
BRCA1	P38398-1.2	F1571W	Neutral	0.289
BRCA1	P38398-1.2	F1571Y	Neutral	0.107
BRCA1	P38398-1.2	S1572A	Neutral	0.021
BRCA1	P38398-1.2	S1572C	Neutral	0.049
BRCA1	P38398-1.2	S1572D	Neutral	0.039
BRCA1	P38398-1.2	S1572E	Neutral	0.057
BRCA1	P38398-1.2	S1572F	Neutral	0.178
BRCA1	P38398-1.2	S1572G	Neutral	0.045
BRCA1	P38398-1.2	S1572H	Neutral	0.096
BRCA1	P38398-1.2	S1572I	Neutral	0.145
BRCA1	P38398-1.2	S1572K	Neutral	0.096
BRCA1	P38398-1.2	S1572L	Neutral	0.145
BRCA1	P38398-1.2	S1572M	Neutral	0.106
BRCA1	P38398-1.2	S1572N	Neutral	0.03
BRCA1	P38398-1.2	S1572P	Neutral	0.053
BRCA1	P38398-1.2	S1572Q	Neutral	0.063
BRCA1	P38398-1.2	S1572R	Neutral	0.169
BRCA1	P38398-1.2	S1572T	Neutral	0.029
BRCA1	P38398-1.2	S1572V	Neutral	0.101
BRCA1	P38398-1.2	S1572W	Neutral	0.365
BRCA1	P38398-1.2	S1572Y	Neutral	0.201
BRCA1	P38398-1.2	D1573A	Neutral	0.05
BRCA1	P38398-1.2	D1573C	Neutral	0.047
BRCA1	P38398-1.2	D1573E	Neutral	0.011
BRCA1	P38398-1.2	D1573F	Neutral	0.103
BRCA1	P38398-1.2	D1573G	Neutral	0.053
BRCA1	P38398-1.2	D1573H	Neutral	0.038
BRCA1	P38398-1.2	D1573I	Neutral	0.083
BRCA1	P38398-1.2	D1573K	Neutral	0.055
BRCA1	P38398-1.2	D1573L	Neutral	0.115
BRCA1	P38398-1.2	D1573M	Neutral	0.084
BRCA1	P38398-1.2	D1573N	Neutral	0.012
BRCA1	P38398-1.2	D1573P	Neutral	0.021
BRCA1	P38398-1.2	D1573Q	Neutral	0.025
BRCA1	P38398-1.2	D1573R	Neutral	0.1
BRCA1	P38398-1.2	D1573S	Neutral	0.022
BRCA1	P38398-1.2	D1573T	Neutral	0.022
BRCA1	P38398-1.2	D1573V	Neutral	0.056
BRCA1	P38398-1.2	D1573W	Neutral	0.234
BRCA1	P38398-1.2	D1573Y	Neutral	0.118
BRCA1	P38398-1.2	D1574A	Neutral	0.067
BRCA1	P38398-1.2	D1574C	Neutral	0.063
BRCA1	P38398-1.2	D1574E	Neutral	0.015
BRCA1	P38398-1.2	D1574F	Neutral	0.136
BRCA1	P38398-1.2	D1574G	Neutral	0.071
BRCA1	P38398-1.2	D1574H	Neutral	0.051
BRCA1	P38398-1.2	D1574I	Neutral	0.11
BRCA1	P38398-1.2	D1574K	Neutral	0.074
BRCA1	P38398-1.2	D1574L	Neutral	0.151
BRCA1	P38398-1.2	D1574M	Neutral	0.111
BRCA1	P38398-1.2	D1574N	Neutral	0.016
BRCA1	P38398-1.2	D1574P	Neutral	0.029
BRCA1	P38398-1.2	D1574Q	Neutral	0.033
BRCA1	P38398-1.2	D1574R	Neutral	0.133
BRCA1	P38398-1.2	D1574S	Neutral	0.03
BRCA1	P38398-1.2	D1574T	Neutral	0.03
BRCA1	P38398-1.2	D1574V	Neutral	0.076
BRCA1	P38398-1.2	D1574W	Neutral	0.295
BRCA1	P38398-1.2	D1574Y	Neutral	0.155
BRCA1	P38398-1.2	P1575A	Neutral	0.364
BRCA1	P38398-1.2	P1575C	Neutral	0.438
BRCA1	P38398-1.2	P1575D	Neutral	0.256
BRCA1	P38398-1.2	P1575E	Neutral	0.34
BRCA1	P38398-1.2	P1575F	Pathogenic	0.733
BRCA1	P38398-1.2	P1575G	Pathogenic	0.555
BRCA1	P38398-1.2	P1575H	Neutral	0.478
BRCA1	P38398-1.2	P1575I	Pathogenic	0.599
BRCA1	P38398-1.2	P1575K	Neutral	0.476
BRCA1	P38398-1.2	P1575L	Pathogenic	0.599
BRCA1	P38398-1.2	P1575M	Pathogenic	0.512
BRCA1	P38398-1.2	P1575N	Neutral	0.357
BRCA1	P38398-1.2	P1575Q	Neutral	0.367
BRCA1	P38398-1.2	P1575R	Pathogenic	0.636
BRCA1	P38398-1.2	P1575S	Neutral	0.332
BRCA1	P38398-1.2	P1575T	Neutral	0.268
BRCA1	P38398-1.2	P1575V	Neutral	0.408
BRCA1	P38398-1.2	P1575W	Pathogenic	0.835
BRCA1	P38398-1.2	P1575Y	Pathogenic	0.689
BRCA1	P38398-1.2	E1576A	Neutral	0.107
BRCA1	P38398-1.2	E1576C	Neutral	0.187
BRCA1	P38398-1.2	E1576D	Neutral	0.023
BRCA1	P38398-1.2	E1576F	Neutral	0.144
BRCA1	P38398-1.2	E1576G	Neutral	0.208
BRCA1	P38398-1.2	E1576H	Neutral	0.038
BRCA1	P38398-1.2	E1576I	Neutral	0.116
BRCA1	P38398-1.2	E1576K	Neutral	0.039
BRCA1	P38398-1.2	E1576L	Neutral	0.117
BRCA1	P38398-1.2	E1576M	Neutral	0.085
BRCA1	P38398-1.2	E1576N	Neutral	0.042
BRCA1	P38398-1.2	E1576P	Neutral	0.066
BRCA1	P38398-1.2	E1576Q	Neutral	0.017
BRCA1	P38398-1.2	E1576R	Neutral	0.073
BRCA1	P38398-1.2	E1576S	Neutral	0.068
BRCA1	P38398-1.2	E1576T	Neutral	0.063
BRCA1	P38398-1.2	E1576V	Neutral	0.068
BRCA1	P38398-1.2	E1576W	Neutral	0.237
BRCA1	P38398-1.2	E1576Y	Neutral	0.12
BRCA1	P38398-1.2	S1577A	Neutral	0.021
BRCA1	P38398-1.2	S1577C	Neutral	0.048
BRCA1	P38398-1.2	S1577D	Neutral	0.038
BRCA1	P38398-1.2	S1577E	Neutral	0.056
BRCA1	P38398-1.2	S1577F	Neutral	0.175
BRCA1	P38398-1.2	S1577G	Neutral	0.045
BRCA1	P38398-1.2	S1577H	Neutral	0.094
BRCA1	P38398-1.2	S1577I	Neutral	0.142
BRCA1	P38398-1.2	S1577K	Neutral	0.094
BRCA1	P38398-1.2	S1577L	Neutral	0.143
BRCA1	P38398-1.2	S1577M	Neutral	0.104
BRCA1	P38398-1.2	S1577N	Neutral	0.03
BRCA1	P38398-1.2	S1577P	Neutral	0.052
BRCA1	P38398-1.2	S1577Q	Neutral	0.062
BRCA1	P38398-1.2	S1577R	Neutral	0.167
BRCA1	P38398-1.2	S1577T	Neutral	0.028
BRCA1	P38398-1.2	S1577V	Neutral	0.099
BRCA1	P38398-1.2	S1577W	Neutral	0.36
BRCA1	P38398-1.2	S1577Y	Neutral	0.197
BRCA1	P38398-1.2	D1578A	Neutral	0.059
BRCA1	P38398-1.2	D1578C	Neutral	0.055
BRCA1	P38398-1.2	D1578E	Neutral	0.013
BRCA1	P38398-1.2	D1578F	Neutral	0.12
BRCA1	P38398-1.2	D1578G	Neutral	0.063
BRCA1	P38398-1.2	D1578H	Neutral	0.045
BRCA1	P38398-1.2	D1578I	Neutral	0.097
BRCA1	P38398-1.2	D1578K	Neutral	0.065
BRCA1	P38398-1.2	D1578L	Neutral	0.134
BRCA1	P38398-1.2	D1578M	Neutral	0.098
BRCA1	P38398-1.2	D1578N	Neutral	0.014
BRCA1	P38398-1.2	D1578P	Neutral	0.025
BRCA1	P38398-1.2	D1578Q	Neutral	0.029
BRCA1	P38398-1.2	D1578R	Neutral	0.117
BRCA1	P38398-1.2	D1578S	Neutral	0.026
BRCA1	P38398-1.2	D1578T	Neutral	0.026
BRCA1	P38398-1.2	D1578V	Neutral	0.066
BRCA1	P38398-1.2	D1578W	Neutral	0.266
BRCA1	P38398-1.2	D1578Y	Neutral	0.137
BRCA1	P38398-1.2	P1579A	Neutral	0.084
BRCA1	P38398-1.2	P1579C	Neutral	0.11
BRCA1	P38398-1.2	P1579D	Neutral	0.052
BRCA1	P38398-1.2	P1579E	Neutral	0.076
BRCA1	P38398-1.2	P1579F	Neutral	0.304
BRCA1	P38398-1.2	P1579G	Neutral	0.166
BRCA1	P38398-1.2	P1579H	Neutral	0.128
BRCA1	P38398-1.2	P1579I	Neutral	0.192
BRCA1	P38398-1.2	P1579K	Neutral	0.127
BRCA1	P38398-1.2	P1579L	Neutral	0.193
BRCA1	P38398-1.2	P1579M	Neutral	0.143
BRCA1	P38398-1.2	P1579N	Neutral	0.081
BRCA1	P38398-1.2	P1579Q	Neutral	0.084
BRCA1	P38398-1.2	P1579R	Neutral	0.218
BRCA1	P38398-1.2	P1579S	Neutral	0.073
BRCA1	P38398-1.2	P1579T	Neutral	0.055
BRCA1	P38398-1.2	P1579V	Neutral	0.099
BRCA1	P38398-1.2	P1579W	Neutral	0.447
BRCA1	P38398-1.2	P1579Y	Neutral	0.261
BRCA1	P38398-1.2	S1580A	Neutral	0.004
BRCA1	P38398-1.2	S1580C	Neutral	0.01
BRCA1	P38398-1.2	S1580D	Neutral	0.008
BRCA1	P38398-1.2	S1580E	Neutral	0.012
BRCA1	P38398-1.2	S1580F	Neutral	0.041
BRCA1	P38398-1.2	S1580G	Neutral	0.009
BRCA1	P38398-1.2	S1580H	Neutral	0.021
BRCA1	P38398-1.2	S1580I	Neutral	0.033
BRCA1	P38398-1.2	S1580K	Neutral	0.021
BRCA1	P38398-1.2	S1580L	Neutral	0.033
BRCA1	P38398-1.2	S1580M	Neutral	0.023
BRCA1	P38398-1.2	S1580N	Neutral	0.006
BRCA1	P38398-1.2	S1580P	Neutral	0.011
BRCA1	P38398-1.2	S1580Q	Neutral	0.013
BRCA1	P38398-1.2	S1580R	Neutral	0.039
BRCA1	P38398-1.2	S1580T	Neutral	0.006
BRCA1	P38398-1.2	S1580V	Neutral	0.022
BRCA1	P38398-1.2	S1580W	Neutral	0.103
BRCA1	P38398-1.2	S1580Y	Neutral	0.048
BRCA1	P38398-1.2	E1581A	Neutral	0.017
BRCA1	P38398-1.2	E1581C	Neutral	0.032
BRCA1	P38398-1.2	E1581D	Neutral	0.003
BRCA1	P38398-1.2	E1581F	Neutral	0.024
BRCA1	P38398-1.2	E1581G	Neutral	0.036
BRCA1	P38398-1.2	E1581H	Neutral	0.006
BRCA1	P38398-1.2	E1581I	Neutral	0.018
BRCA1	P38398-1.2	E1581K	Neutral	0.006
BRCA1	P38398-1.2	E1581L	Neutral	0.019
BRCA1	P38398-1.2	E1581M	Neutral	0.013
BRCA1	P38398-1.2	E1581N	Neutral	0.006
BRCA1	P38398-1.2	E1581P	Neutral	0.01
BRCA1	P38398-1.2	E1581Q	Neutral	0.003
BRCA1	P38398-1.2	E1581R	Neutral	0.011
BRCA1	P38398-1.2	E1581S	Neutral	0.01
BRCA1	P38398-1.2	E1581T	Neutral	0.009
BRCA1	P38398-1.2	E1581V	Neutral	0.01
BRCA1	P38398-1.2	E1581W	Neutral	0.043
BRCA1	P38398-1.2	E1581Y	Neutral	0.019
BRCA1	P38398-1.2	D1582A	Neutral	0.052
BRCA1	P38398-1.2	D1582C	Neutral	0.048
BRCA1	P38398-1.2	D1582E	Neutral	0.011
BRCA1	P38398-1.2	D1582F	Neutral	0.106
BRCA1	P38398-1.2	D1582G	Neutral	0.055
BRCA1	P38398-1.2	D1582H	Neutral	0.039
BRCA1	P38398-1.2	D1582I	Neutral	0.085
BRCA1	P38398-1.2	D1582K	Neutral	0.057
BRCA1	P38398-1.2	D1582L	Neutral	0.118
BRCA1	P38398-1.2	D1582M	Neutral	0.086
BRCA1	P38398-1.2	D1582N	Neutral	0.012
BRCA1	P38398-1.2	D1582P	Neutral	0.022
BRCA1	P38398-1.2	D1582Q	Neutral	0.025
BRCA1	P38398-1.2	D1582R	Neutral	0.104
BRCA1	P38398-1.2	D1582S	Neutral	0.023
BRCA1	P38398-1.2	D1582T	Neutral	0.023
BRCA1	P38398-1.2	D1582V	Neutral	0.058
BRCA1	P38398-1.2	D1582W	Neutral	0.24
BRCA1	P38398-1.2	D1582Y	Neutral	0.121
BRCA1	P38398-1.2	R1583A	Neutral	0.117
BRCA1	P38398-1.2	R1583C	Neutral	0.15
BRCA1	P38398-1.2	R1583D	Neutral	0.102
BRCA1	P38398-1.2	R1583E	Neutral	0.035
BRCA1	P38398-1.2	R1583F	Neutral	0.055
BRCA1	P38398-1.2	R1583G	Neutral	0.226
BRCA1	P38398-1.2	R1583H	Neutral	0.029
BRCA1	P38398-1.2	R1583I	Neutral	0.07
BRCA1	P38398-1.2	R1583K	Neutral	0.01
BRCA1	P38398-1.2	R1583L	Neutral	0.05
BRCA1	P38398-1.2	R1583M	Neutral	0.035
BRCA1	P38398-1.2	R1583N	Neutral	0.047
BRCA1	P38398-1.2	R1583P	Neutral	0.102
BRCA1	P38398-1.2	R1583Q	Neutral	0.022
BRCA1	P38398-1.2	R1583S	Neutral	0.104
BRCA1	P38398-1.2	R1583T	Neutral	0.069
BRCA1	P38398-1.2	R1583V	Neutral	0.104
BRCA1	P38398-1.2	R1583W	Neutral	0.057
BRCA1	P38398-1.2	R1583Y	Neutral	0.035
BRCA1	P38398-1.2	A1584C	Neutral	0.047
BRCA1	P38398-1.2	A1584D	Neutral	0.103
BRCA1	P38398-1.2	A1584E	Neutral	0.106
BRCA1	P38398-1.2	A1584F	Neutral	0.231
BRCA1	P38398-1.2	A1584G	Neutral	0.048
BRCA1	P38398-1.2	A1584H	Neutral	0.175
BRCA1	P38398-1.2	A1584I	Neutral	0.141
BRCA1	P38398-1.2	A1584K	Neutral	0.174
BRCA1	P38398-1.2	A1584L	Neutral	0.141
BRCA1	P38398-1.2	A1584M	Neutral	0.142
BRCA1	P38398-1.2	A1584N	Neutral	0.114
BRCA1	P38398-1.2	A1584P	Neutral	0.073
BRCA1	P38398-1.2	A1584Q	Neutral	0.118
BRCA1	P38398-1.2	A1584R	Neutral	0.219
BRCA1	P38398-1.2	A1584S	Neutral	0.025
BRCA1	P38398-1.2	A1584T	Neutral	0.056
BRCA1	P38398-1.2	A1584V	Neutral	0.07
BRCA1	P38398-1.2	A1584W	Neutral	0.444
BRCA1	P38398-1.2	A1584Y	Neutral	0.259
BRCA1	P38398-1.2	P1585A	Neutral	0.136
BRCA1	P38398-1.2	P1585C	Neutral	0.176
BRCA1	P38398-1.2	P1585D	Neutral	0.086
BRCA1	P38398-1.2	P1585E	Neutral	0.124
BRCA1	P38398-1.2	P1585F	Neutral	0.429
BRCA1	P38398-1.2	P1585G	Neutral	0.255
BRCA1	P38398-1.2	P1585H	Neutral	0.201
BRCA1	P38398-1.2	P1585I	Neutral	0.291
BRCA1	P38398-1.2	P1585K	Neutral	0.2
BRCA1	P38398-1.2	P1585L	Neutral	0.291
BRCA1	P38398-1.2	P1585M	Neutral	0.223
BRCA1	P38398-1.2	P1585N	Neutral	0.132
BRCA1	P38398-1.2	P1585Q	Neutral	0.137
BRCA1	P38398-1.2	P1585R	Neutral	0.324
BRCA1	P38398-1.2	P1585S	Neutral	0.12
BRCA1	P38398-1.2	P1585T	Neutral	0.091
BRCA1	P38398-1.2	P1585V	Neutral	0.159
BRCA1	P38398-1.2	P1585W	Pathogenic	0.582
BRCA1	P38398-1.2	P1585Y	Neutral	0.378
BRCA1	P38398-1.2	E1586A	Neutral	0.13
BRCA1	P38398-1.2	E1586C	Neutral	0.225
BRCA1	P38398-1.2	E1586D	Neutral	0.029
BRCA1	P38398-1.2	E1586F	Neutral	0.175
BRCA1	P38398-1.2	E1586G	Neutral	0.249
BRCA1	P38398-1.2	E1586H	Neutral	0.048
BRCA1	P38398-1.2	E1586I	Neutral	0.142
BRCA1	P38398-1.2	E1586K	Neutral	0.049
BRCA1	P38398-1.2	E1586L	Neutral	0.142
BRCA1	P38398-1.2	E1586M	Neutral	0.104
BRCA1	P38398-1.2	E1586N	Neutral	0.053
BRCA1	P38398-1.2	E1586P	Neutral	0.082
BRCA1	P38398-1.2	E1586Q	Neutral	0.022
BRCA1	P38398-1.2	E1586R	Neutral	0.09
BRCA1	P38398-1.2	E1586S	Neutral	0.084
BRCA1	P38398-1.2	E1586T	Neutral	0.078
BRCA1	P38398-1.2	E1586V	Neutral	0.084
BRCA1	P38398-1.2	E1586W	Neutral	0.281
BRCA1	P38398-1.2	E1586Y	Neutral	0.146
BRCA1	P38398-1.2	S1587A	Neutral	0.005
BRCA1	P38398-1.2	S1587C	Neutral	0.011
BRCA1	P38398-1.2	S1587D	Neutral	0.009
BRCA1	P38398-1.2	S1587E	Neutral	0.013
BRCA1	P38398-1.2	S1587F	Neutral	0.046
BRCA1	P38398-1.2	S1587G	Neutral	0.011
BRCA1	P38398-1.2	S1587H	Neutral	0.023
BRCA1	P38398-1.2	S1587I	Neutral	0.037
BRCA1	P38398-1.2	S1587K	Neutral	0.023
BRCA1	P38398-1.2	S1587L	Neutral	0.037
BRCA1	P38398-1.2	S1587M	Neutral	0.026
BRCA1	P38398-1.2	S1587N	Neutral	0.007
BRCA1	P38398-1.2	S1587P	Neutral	0.013
BRCA1	P38398-1.2	S1587Q	Neutral	0.015
BRCA1	P38398-1.2	S1587R	Neutral	0.044
BRCA1	P38398-1.2	S1587T	Neutral	0.007
BRCA1	P38398-1.2	S1587V	Neutral	0.025
BRCA1	P38398-1.2	S1587W	Neutral	0.115
BRCA1	P38398-1.2	S1587Y	Neutral	0.054
BRCA1	P38398-1.2	A1588C	Neutral	0.122
BRCA1	P38398-1.2	A1588D	Neutral	0.242
BRCA1	P38398-1.2	A1588E	Neutral	0.249
BRCA1	P38398-1.2	A1588F	Neutral	0.458
BRCA1	P38398-1.2	A1588G	Neutral	0.123
BRCA1	P38398-1.2	A1588H	Neutral	0.372
BRCA1	P38398-1.2	A1588I	Neutral	0.315
BRCA1	P38398-1.2	A1588K	Neutral	0.37
BRCA1	P38398-1.2	A1588L	Neutral	0.315
BRCA1	P38398-1.2	A1588M	Neutral	0.317
BRCA1	P38398-1.2	A1588N	Neutral	0.264
BRCA1	P38398-1.2	A1588P	Neutral	0.18
BRCA1	P38398-1.2	A1588Q	Neutral	0.272
BRCA1	P38398-1.2	A1588R	Neutral	0.44
BRCA1	P38398-1.2	A1588S	Neutral	0.068
BRCA1	P38398-1.2	A1588T	Neutral	0.141
BRCA1	P38398-1.2	A1588V	Neutral	0.175
BRCA1	P38398-1.2	A1588W	Pathogenic	0.691
BRCA1	P38398-1.2	A1588Y	Neutral	0.495
BRCA1	P38398-1.2	R1589A	Neutral	0.019
BRCA1	P38398-1.2	R1589C	Neutral	0.026
BRCA1	P38398-1.2	R1589D	Neutral	0.017
BRCA1	P38398-1.2	R1589E	Neutral	0.005
BRCA1	P38398-1.2	R1589F	Neutral	0.009
BRCA1	P38398-1.2	R1589G	Neutral	0.042
BRCA1	P38398-1.2	R1589H	Neutral	0.004
BRCA1	P38398-1.2	R1589I	Neutral	0.011
BRCA1	P38398-1.2	R1589K	Neutral	0.002
BRCA1	P38398-1.2	R1589L	Neutral	0.008
BRCA1	P38398-1.2	R1589M	Neutral	0.005
BRCA1	P38398-1.2	R1589N	Neutral	0.007
BRCA1	P38398-1.2	R1589P	Neutral	0.017
BRCA1	P38398-1.2	R1589Q	Neutral	0.003
BRCA1	P38398-1.2	R1589S	Neutral	0.017
BRCA1	P38398-1.2	R1589T	Neutral	0.011
BRCA1	P38398-1.2	R1589V	Neutral	0.017
BRCA1	P38398-1.2	R1589W	Neutral	0.009
BRCA1	P38398-1.2	R1589Y	Neutral	0.005
BRCA1	P38398-1.2	V1590A	Neutral	0.103
BRCA1	P38398-1.2	V1590C	Neutral	0.099
BRCA1	P38398-1.2	V1590D	Neutral	0.164
BRCA1	P38398-1.2	V1590E	Neutral	0.099
BRCA1	P38398-1.2	V1590F	Neutral	0.122
BRCA1	P38398-1.2	V1590G	Neutral	0.341
BRCA1	P38398-1.2	V1590H	Neutral	0.163
BRCA1	P38398-1.2	V1590I	Neutral	0.025
BRCA1	P38398-1.2	V1590K	Neutral	0.162
BRCA1	P38398-1.2	V1590L	Neutral	0.05
BRCA1	P38398-1.2	V1590M	Neutral	0.05
BRCA1	P38398-1.2	V1590N	Neutral	0.15
BRCA1	P38398-1.2	V1590P	Neutral	0.125
BRCA1	P38398-1.2	V1590Q	Neutral	0.11
BRCA1	P38398-1.2	V1590R	Neutral	0.271
BRCA1	P38398-1.2	V1590S	Neutral	0.171
BRCA1	P38398-1.2	V1590T	Neutral	0.06
BRCA1	P38398-1.2	V1590W	Neutral	0.347
BRCA1	P38398-1.2	V1590Y	Neutral	0.138
BRCA1	P38398-1.2	G1591A	Neutral	0.004
BRCA1	P38398-1.2	G1591C	Neutral	0.017
BRCA1	P38398-1.2	G1591D	Neutral	0.009
BRCA1	P38398-1.2	G1591E	Neutral	0.02
BRCA1	P38398-1.2	G1591F	Neutral	0.048
BRCA1	P38398-1.2	G1591H	Neutral	0.024
BRCA1	P38398-1.2	G1591I	Neutral	0.053
BRCA1	P38398-1.2	G1591K	Neutral	0.034
BRCA1	P38398-1.2	G1591L	Neutral	0.054
BRCA1	P38398-1.2	G1591M	Neutral	0.038
BRCA1	P38398-1.2	G1591N	Neutral	0.007
BRCA1	P38398-1.2	G1591P	Neutral	0.013
BRCA1	P38398-1.2	G1591Q	Neutral	0.022
BRCA1	P38398-1.2	G1591R	Neutral	0.045
BRCA1	P38398-1.2	G1591S	Neutral	0.004
BRCA1	P38398-1.2	G1591T	Neutral	0.014
BRCA1	P38398-1.2	G1591V	Neutral	0.025
BRCA1	P38398-1.2	G1591W	Neutral	0.06
BRCA1	P38398-1.2	G1591Y	Neutral	0.055
BRCA1	P38398-1.2	N1592A	Neutral	0.013
BRCA1	P38398-1.2	N1592C	Neutral	0.012
BRCA1	P38398-1.2	N1592D	Neutral	0.003
BRCA1	P38398-1.2	N1592E	Neutral	0.004
BRCA1	P38398-1.2	N1592F	Neutral	0.022
BRCA1	P38398-1.2	N1592G	Neutral	0.01
BRCA1	P38398-1.2	N1592H	Neutral	0.004
BRCA1	P38398-1.2	N1592I	Neutral	0.018
BRCA1	P38398-1.2	N1592K	Neutral	0.008
BRCA1	P38398-1.2	N1592L	Neutral	0.018
BRCA1	P38398-1.2	N1592M	Neutral	0.012
BRCA1	P38398-1.2	N1592P	Neutral	0.008
BRCA1	P38398-1.2	N1592Q	Neutral	0.005
BRCA1	P38398-1.2	N1592R	Neutral	0.011
BRCA1	P38398-1.2	N1592S	Neutral	0.004
BRCA1	P38398-1.2	N1592T	Neutral	0.004
BRCA1	P38398-1.2	N1592V	Neutral	0.012
BRCA1	P38398-1.2	N1592W	Neutral	0.057
BRCA1	P38398-1.2	N1592Y	Neutral	0.018
BRCA1	P38398-1.2	I1593A	Neutral	0.014
BRCA1	P38398-1.2	I1593C	Neutral	0.009
BRCA1	P38398-1.2	I1593D	Neutral	0.017
BRCA1	P38398-1.2	I1593E	Neutral	0.011
BRCA1	P38398-1.2	I1593F	Neutral	0.004
BRCA1	P38398-1.2	I1593G	Neutral	0.061
BRCA1	P38398-1.2	I1593H	Neutral	0.009
BRCA1	P38398-1.2	I1593K	Neutral	0.01
BRCA1	P38398-1.2	I1593L	Neutral	0.001
BRCA1	P38398-1.2	I1593M	Neutral	0.002
BRCA1	P38398-1.2	I1593N	Neutral	0.015
BRCA1	P38398-1.2	I1593P	Neutral	0.018
BRCA1	P38398-1.2	I1593Q	Neutral	0.01
BRCA1	P38398-1.2	I1593R	Neutral	0.014
BRCA1	P38398-1.2	I1593S	Neutral	0.018
BRCA1	P38398-1.2	I1593T	Neutral	0.008
BRCA1	P38398-1.2	I1593V	Neutral	0.001
BRCA1	P38398-1.2	I1593W	Neutral	0.02
BRCA1	P38398-1.2	I1593Y	Neutral	0.006
BRCA1	P38398-1.2	P1594A	Pathogenic	0.51
BRCA1	P38398-1.2	P1594C	Pathogenic	0.586
BRCA1	P38398-1.2	P1594D	Neutral	0.385
BRCA1	P38398-1.2	P1594E	Neutral	0.483
BRCA1	P38398-1.2	P1594F	Pathogenic	0.833
BRCA1	P38398-1.2	P1594G	Pathogenic	0.694
BRCA1	P38398-1.2	P1594H	Pathogenic	0.625
BRCA1	P38398-1.2	P1594I	Pathogenic	0.731
BRCA1	P38398-1.2	P1594K	Pathogenic	0.623
BRCA1	P38398-1.2	P1594L	Pathogenic	0.731
BRCA1	P38398-1.2	P1594M	Pathogenic	0.656
BRCA1	P38398-1.2	P1594N	Pathogenic	0.502
BRCA1	P38398-1.2	P1594Q	Pathogenic	0.513
BRCA1	P38398-1.2	P1594R	Pathogenic	0.76
BRCA1	P38398-1.2	P1594S	Neutral	0.475
BRCA1	P38398-1.2	P1594T	Neutral	0.4
BRCA1	P38398-1.2	P1594V	Pathogenic	0.556
BRCA1	P38398-1.2	P1594W	Pathogenic	0.902
BRCA1	P38398-1.2	P1594Y	Pathogenic	0.801
BRCA1	P38398-1.2	S1595A	Neutral	0.003
BRCA1	P38398-1.2	S1595C	Neutral	0.006
BRCA1	P38398-1.2	S1595D	Neutral	0.005
BRCA1	P38398-1.2	S1595E	Neutral	0.007
BRCA1	P38398-1.2	S1595F	Neutral	0.026
BRCA1	P38398-1.2	S1595G	Neutral	0.006
BRCA1	P38398-1.2	S1595H	Neutral	0.013
BRCA1	P38398-1.2	S1595I	Neutral	0.02
BRCA1	P38398-1.2	S1595K	Neutral	0.013
BRCA1	P38398-1.2	S1595L	Neutral	0.02
BRCA1	P38398-1.2	S1595M	Neutral	0.014
BRCA1	P38398-1.2	S1595N	Neutral	0.004
BRCA1	P38398-1.2	S1595P	Neutral	0.007
BRCA1	P38398-1.2	S1595Q	Neutral	0.008
BRCA1	P38398-1.2	S1595R	Neutral	0.024
BRCA1	P38398-1.2	S1595T	Neutral	0.004
BRCA1	P38398-1.2	S1595V	Neutral	0.013
BRCA1	P38398-1.2	S1595W	Neutral	0.065
BRCA1	P38398-1.2	S1595Y	Neutral	0.03
BRCA1	P38398-1.2	S1596A	Neutral	0.085
BRCA1	P38398-1.2	S1596C	Neutral	0.181
BRCA1	P38398-1.2	S1596D	Neutral	0.147
BRCA1	P38398-1.2	S1596E	Neutral	0.205
BRCA1	P38398-1.2	S1596F	Neutral	0.481
BRCA1	P38398-1.2	S1596G	Neutral	0.169
BRCA1	P38398-1.2	S1596H	Neutral	0.313
BRCA1	P38398-1.2	S1596I	Neutral	0.421
BRCA1	P38398-1.2	S1596K	Neutral	0.313
BRCA1	P38398-1.2	S1596L	Neutral	0.421
BRCA1	P38398-1.2	S1596M	Neutral	0.338
BRCA1	P38398-1.2	S1596N	Neutral	0.118
BRCA1	P38398-1.2	S1596P	Neutral	0.195
BRCA1	P38398-1.2	S1596Q	Neutral	0.225
BRCA1	P38398-1.2	S1596R	Neutral	0.467
BRCA1	P38398-1.2	S1596T	Neutral	0.112
BRCA1	P38398-1.2	S1596V	Neutral	0.325
BRCA1	P38398-1.2	S1596W	Pathogenic	0.711
BRCA1	P38398-1.2	S1596Y	Pathogenic	0.519
BRCA1	P38398-1.2	T1597A	Neutral	0.074
BRCA1	P38398-1.2	T1597C	Neutral	0.069
BRCA1	P38398-1.2	T1597D	Neutral	0.062
BRCA1	P38398-1.2	T1597E	Neutral	0.083
BRCA1	P38398-1.2	T1597F	Neutral	0.187
BRCA1	P38398-1.2	T1597G	Neutral	0.201
BRCA1	P38398-1.2	T1597H	Neutral	0.139
BRCA1	P38398-1.2	T1597I	Neutral	0.111
BRCA1	P38398-1.2	T1597K	Neutral	0.138
BRCA1	P38398-1.2	T1597L	Neutral	0.111
BRCA1	P38398-1.2	T1597M	Neutral	0.112
BRCA1	P38398-1.2	T1597N	Neutral	0.045
BRCA1	P38398-1.2	T1597P	Neutral	0.064
BRCA1	P38398-1.2	T1597Q	Neutral	0.093
BRCA1	P38398-1.2	T1597R	Neutral	0.177
BRCA1	P38398-1.2	T1597S	Neutral	0.046
BRCA1	P38398-1.2	T1597V	Neutral	0.055
BRCA1	P38398-1.2	T1597W	Neutral	0.298
BRCA1	P38398-1.2	T1597Y	Neutral	0.211
BRCA1	P38398-1.2	S1598A	Neutral	0.15
BRCA1	P38398-1.2	S1598C	Neutral	0.296
BRCA1	P38398-1.2	S1598D	Neutral	0.247
BRCA1	P38398-1.2	S1598E	Neutral	0.329
BRCA1	P38398-1.2	S1598F	Pathogenic	0.639
BRCA1	P38398-1.2	S1598G	Neutral	0.28
BRCA1	P38398-1.2	S1598H	Neutral	0.465
BRCA1	P38398-1.2	S1598I	Pathogenic	0.581
BRCA1	P38398-1.2	S1598K	Neutral	0.465
BRCA1	P38398-1.2	S1598L	Pathogenic	0.581
BRCA1	P38398-1.2	S1598M	Neutral	0.493
BRCA1	P38398-1.2	S1598N	Neutral	0.204
BRCA1	P38398-1.2	S1598P	Neutral	0.316
BRCA1	P38398-1.2	S1598Q	Neutral	0.356
BRCA1	P38398-1.2	S1598R	Pathogenic	0.625
BRCA1	P38398-1.2	S1598T	Neutral	0.194
BRCA1	P38398-1.2	S1598V	Neutral	0.479
BRCA1	P38398-1.2	S1598W	Pathogenic	0.825
BRCA1	P38398-1.2	S1598Y	Pathogenic	0.673
BRCA1	P38398-1.2	A1599C	Neutral	0.247
BRCA1	P38398-1.2	A1599D	Neutral	0.43
BRCA1	P38398-1.2	A1599E	Neutral	0.439
BRCA1	P38398-1.2	A1599F	Pathogenic	0.665
BRCA1	P38398-1.2	A1599G	Neutral	0.248
BRCA1	P38398-1.2	A1599H	Pathogenic	0.583
BRCA1	P38398-1.2	A1599I	Pathogenic	0.519
BRCA1	P38398-1.2	A1599K	Pathogenic	0.581
BRCA1	P38398-1.2	A1599L	Pathogenic	0.52
BRCA1	P38398-1.2	A1599M	Pathogenic	0.522
BRCA1	P38398-1.2	A1599N	Neutral	0.458
BRCA1	P38398-1.2	A1599P	Neutral	0.341
BRCA1	P38398-1.2	A1599Q	Neutral	0.468
BRCA1	P38398-1.2	A1599R	Pathogenic	0.649
BRCA1	P38398-1.2	A1599S	Neutral	0.147
BRCA1	P38398-1.2	A1599T	Neutral	0.279
BRCA1	P38398-1.2	A1599V	Neutral	0.332
BRCA1	P38398-1.2	A1599W	Pathogenic	0.841
BRCA1	P38398-1.2	A1599Y	Pathogenic	0.697
BRCA1	P38398-1.2	L1600A	Neutral	0.266
BRCA1	P38398-1.2	L1600C	Neutral	0.194
BRCA1	P38398-1.2	L1600D	Neutral	0.384
BRCA1	P38398-1.2	L1600E	Neutral	0.225
BRCA1	P38398-1.2	L1600F	Neutral	0.085
BRCA1	P38398-1.2	L1600G	Pathogenic	0.621
BRCA1	P38398-1.2	L1600H	Neutral	0.194
BRCA1	P38398-1.2	L1600I	Neutral	0.034
BRCA1	P38398-1.2	L1600K	Neutral	0.155
BRCA1	P38398-1.2	L1600M	Neutral	0.034
BRCA1	P38398-1.2	L1600N	Neutral	0.28
BRCA1	P38398-1.2	L1600P	Neutral	0.313
BRCA1	P38398-1.2	L1600Q	Neutral	0.154
BRCA1	P38398-1.2	L1600R	Neutral	0.197
BRCA1	P38398-1.2	L1600S	Neutral	0.312
BRCA1	P38398-1.2	L1600T	Neutral	0.169
BRCA1	P38398-1.2	L1600V	Neutral	0.071
BRCA1	P38398-1.2	L1600W	Neutral	0.263
BRCA1	P38398-1.2	L1600Y	Neutral	0.131
BRCA1	P38398-1.2	K1601A	Pathogenic	0.544
BRCA1	P38398-1.2	K1601C	Pathogenic	0.615
BRCA1	P38398-1.2	K1601D	Neutral	0.417
BRCA1	P38398-1.2	K1601E	Neutral	0.187
BRCA1	P38398-1.2	K1601F	Neutral	0.346
BRCA1	P38398-1.2	K1601G	Pathogenic	0.725
BRCA1	P38398-1.2	K1601H	Neutral	0.278
BRCA1	P38398-1.2	K1601I	Neutral	0.403
BRCA1	P38398-1.2	K1601L	Neutral	0.32
BRCA1	P38398-1.2	K1601M	Neutral	0.248
BRCA1	P38398-1.2	K1601N	Neutral	0.307
BRCA1	P38398-1.2	K1601P	Neutral	0.415
BRCA1	P38398-1.2	K1601Q	Neutral	0.17
BRCA1	P38398-1.2	K1601R	Neutral	0.108
BRCA1	P38398-1.2	K1601S	Neutral	0.422
BRCA1	P38398-1.2	K1601T	Neutral	0.401
BRCA1	P38398-1.2	K1601V	Neutral	0.42
BRCA1	P38398-1.2	K1601W	Neutral	0.494
BRCA1	P38398-1.2	K1601Y	Neutral	0.299
BRCA1	P38398-1.2	V1602A	Neutral	0.017
BRCA1	P38398-1.2	V1602C	Neutral	0.016
BRCA1	P38398-1.2	V1602D	Neutral	0.029
BRCA1	P38398-1.2	V1602E	Neutral	0.016
BRCA1	P38398-1.2	V1602F	Neutral	0.021
BRCA1	P38398-1.2	V1602G	Neutral	0.073
BRCA1	P38398-1.2	V1602H	Neutral	0.029
BRCA1	P38398-1.2	V1602I	Neutral	0.004
BRCA1	P38398-1.2	V1602K	Neutral	0.029
BRCA1	P38398-1.2	V1602L	Neutral	0.008
BRCA1	P38398-1.2	V1602M	Neutral	0.008
BRCA1	P38398-1.2	V1602N	Neutral	0.026
BRCA1	P38398-1.2	V1602P	Neutral	0.021
BRCA1	P38398-1.2	V1602Q	Neutral	0.018
BRCA1	P38398-1.2	V1602R	Neutral	0.053
BRCA1	P38398-1.2	V1602S	Neutral	0.03
BRCA1	P38398-1.2	V1602T	Neutral	0.01
BRCA1	P38398-1.2	V1602W	Neutral	0.074
BRCA1	P38398-1.2	V1602Y	Neutral	0.024
BRCA1	P38398-1.2	P1603A	Neutral	0.047
BRCA1	P38398-1.2	P1603C	Neutral	0.063
BRCA1	P38398-1.2	P1603D	Neutral	0.029
BRCA1	P38398-1.2	P1603E	Neutral	0.043
BRCA1	P38398-1.2	P1603F	Neutral	0.192
BRCA1	P38398-1.2	P1603G	Neutral	0.097
BRCA1	P38398-1.2	P1603H	Neutral	0.073
BRCA1	P38398-1.2	P1603I	Neutral	0.114
BRCA1	P38398-1.2	P1603K	Neutral	0.073
BRCA1	P38398-1.2	P1603L	Neutral	0.115
BRCA1	P38398-1.2	P1603M	Neutral	0.083
BRCA1	P38398-1.2	P1603N	Neutral	0.046
BRCA1	P38398-1.2	P1603Q	Neutral	0.048
BRCA1	P38398-1.2	P1603R	Neutral	0.131
BRCA1	P38398-1.2	P1603S	Neutral	0.041
BRCA1	P38398-1.2	P1603T	Neutral	0.031
BRCA1	P38398-1.2	P1603V	Neutral	0.056
BRCA1	P38398-1.2	P1603W	Neutral	0.305
BRCA1	P38398-1.2	P1603Y	Neutral	0.161
BRCA1	P38398-1.2	Q1604A	Pathogenic	0.504
BRCA1	P38398-1.2	Q1604C	Pathogenic	0.577
BRCA1	P38398-1.2	Q1604D	Neutral	0.293
BRCA1	P38398-1.2	Q1604E	Neutral	0.118
BRCA1	P38398-1.2	Q1604F	Pathogenic	0.534
BRCA1	P38398-1.2	Q1604G	Pathogenic	0.692
BRCA1	P38398-1.2	Q1604H	Neutral	0.214
BRCA1	P38398-1.2	Q1604I	Neutral	0.473
BRCA1	P38398-1.2	Q1604K	Neutral	0.215
BRCA1	P38398-1.2	Q1604L	Neutral	0.385
BRCA1	P38398-1.2	Q1604M	Neutral	0.234
BRCA1	P38398-1.2	Q1604N	Neutral	0.271
BRCA1	P38398-1.2	Q1604P	Neutral	0.377
BRCA1	P38398-1.2	Q1604R	Neutral	0.268
BRCA1	P38398-1.2	Q1604S	Neutral	0.383
BRCA1	P38398-1.2	Q1604T	Neutral	0.363
BRCA1	P38398-1.2	Q1604V	Neutral	0.382
BRCA1	P38398-1.2	Q1604W	Pathogenic	0.595
BRCA1	P38398-1.2	Q1604Y	Neutral	0.391
BRCA1	P38398-1.2	L1605A	Neutral	0.011
BRCA1	P38398-1.2	L1605C	Neutral	0.007
BRCA1	P38398-1.2	L1605D	Neutral	0.018
BRCA1	P38398-1.2	L1605E	Neutral	0.009
BRCA1	P38398-1.2	L1605F	Neutral	0.003
BRCA1	P38398-1.2	L1605G	Neutral	0.047
BRCA1	P38398-1.2	L1605H	Neutral	0.007
BRCA1	P38398-1.2	L1605I	Neutral	0.001
BRCA1	P38398-1.2	L1605K	Neutral	0.005
BRCA1	P38398-1.2	L1605M	Neutral	0.001
BRCA1	P38398-1.2	L1605N	Neutral	0.011
BRCA1	P38398-1.2	L1605P	Neutral	0.013
BRCA1	P38398-1.2	L1605Q	Neutral	0.005
BRCA1	P38398-1.2	L1605R	Neutral	0.007
BRCA1	P38398-1.2	L1605S	Neutral	0.013
BRCA1	P38398-1.2	L1605T	Neutral	0.006
BRCA1	P38398-1.2	L1605V	Neutral	0.002
BRCA1	P38398-1.2	L1605W	Neutral	0.011
BRCA1	P38398-1.2	L1605Y	Neutral	0.005
BRCA1	P38398-1.2	K1606A	Neutral	0.167
BRCA1	P38398-1.2	K1606C	Neutral	0.211
BRCA1	P38398-1.2	K1606D	Neutral	0.107
BRCA1	P38398-1.2	K1606E	Neutral	0.037
BRCA1	P38398-1.2	K1606F	Neutral	0.082
BRCA1	P38398-1.2	K1606G	Neutral	0.306
BRCA1	P38398-1.2	K1606H	Neutral	0.061
BRCA1	P38398-1.2	K1606I	Neutral	0.102
BRCA1	P38398-1.2	K1606L	Neutral	0.073
BRCA1	P38398-1.2	K1606M	Neutral	0.052
BRCA1	P38398-1.2	K1606N	Neutral	0.069
BRCA1	P38398-1.2	K1606P	Neutral	0.106
BRCA1	P38398-1.2	K1606Q	Neutral	0.033
BRCA1	P38398-1.2	K1606R	Neutral	0.02
BRCA1	P38398-1.2	K1606S	Neutral	0.109
BRCA1	P38398-1.2	K1606T	Neutral	0.101
BRCA1	P38398-1.2	K1606V	Neutral	0.108
BRCA1	P38398-1.2	K1606W	Neutral	0.141
BRCA1	P38398-1.2	K1606Y	Neutral	0.067
BRCA1	P38398-1.2	V1607A	Neutral	0.134
BRCA1	P38398-1.2	V1607C	Neutral	0.129
BRCA1	P38398-1.2	V1607D	Neutral	0.21
BRCA1	P38398-1.2	V1607E	Neutral	0.129
BRCA1	P38398-1.2	V1607F	Neutral	0.158
BRCA1	P38398-1.2	V1607G	Neutral	0.412
BRCA1	P38398-1.2	V1607H	Neutral	0.209
BRCA1	P38398-1.2	V1607I	Neutral	0.033
BRCA1	P38398-1.2	V1607K	Neutral	0.208
BRCA1	P38398-1.2	V1607L	Neutral	0.067
BRCA1	P38398-1.2	V1607M	Neutral	0.067
BRCA1	P38398-1.2	V1607N	Neutral	0.193
BRCA1	P38398-1.2	V1607P	Neutral	0.163
BRCA1	P38398-1.2	V1607Q	Neutral	0.143
BRCA1	P38398-1.2	V1607R	Neutral	0.335
BRCA1	P38398-1.2	V1607S	Neutral	0.218
BRCA1	P38398-1.2	V1607T	Neutral	0.08
BRCA1	P38398-1.2	V1607W	Neutral	0.418
BRCA1	P38398-1.2	V1607Y	Neutral	0.178
BRCA1	P38398-1.2	A1608C	Neutral	0.01
BRCA1	P38398-1.2	A1608D	Neutral	0.022
BRCA1	P38398-1.2	A1608E	Neutral	0.023
BRCA1	P38398-1.2	A1608F	Neutral	0.056
BRCA1	P38398-1.2	A1608G	Neutral	0.01
BRCA1	P38398-1.2	A1608H	Neutral	0.04
BRCA1	P38398-1.2	A1608I	Neutral	0.031
BRCA1	P38398-1.2	A1608K	Neutral	0.04
BRCA1	P38398-1.2	A1608L	Neutral	0.031
BRCA1	P38398-1.2	A1608M	Neutral	0.032
BRCA1	P38398-1.2	A1608N	Neutral	0.025
BRCA1	P38398-1.2	A1608P	Neutral	0.015
BRCA1	P38398-1.2	A1608Q	Neutral	0.026
BRCA1	P38398-1.2	A1608R	Neutral	0.053
BRCA1	P38398-1.2	A1608S	Neutral	0.005
BRCA1	P38398-1.2	A1608T	Neutral	0.012
BRCA1	P38398-1.2	A1608V	Neutral	0.015
BRCA1	P38398-1.2	A1608W	Neutral	0.137
BRCA1	P38398-1.2	A1608Y	Neutral	0.065
BRCA1	P38398-1.2	E1609A	Neutral	0.044
BRCA1	P38398-1.2	E1609C	Neutral	0.082
BRCA1	P38398-1.2	E1609D	Neutral	0.009
BRCA1	P38398-1.2	E1609F	Neutral	0.061
BRCA1	P38398-1.2	E1609G	Neutral	0.093
BRCA1	P38398-1.2	E1609H	Neutral	0.015
BRCA1	P38398-1.2	E1609I	Neutral	0.049
BRCA1	P38398-1.2	E1609K	Neutral	0.016
BRCA1	P38398-1.2	E1609L	Neutral	0.049
BRCA1	P38398-1.2	E1609M	Neutral	0.035
BRCA1	P38398-1.2	E1609N	Neutral	0.017
BRCA1	P38398-1.2	E1609P	Neutral	0.027
BRCA1	P38398-1.2	E1609Q	Neutral	0.007
BRCA1	P38398-1.2	E1609R	Neutral	0.03
BRCA1	P38398-1.2	E1609S	Neutral	0.028
BRCA1	P38398-1.2	E1609T	Neutral	0.025
BRCA1	P38398-1.2	E1609V	Neutral	0.027
BRCA1	P38398-1.2	E1609W	Neutral	0.108
BRCA1	P38398-1.2	E1609Y	Neutral	0.05
BRCA1	P38398-1.2	S1610A	Neutral	0.008
BRCA1	P38398-1.2	S1610C	Neutral	0.019
BRCA1	P38398-1.2	S1610D	Neutral	0.015
BRCA1	P38398-1.2	S1610E	Neutral	0.022
BRCA1	P38398-1.2	S1610F	Neutral	0.076
BRCA1	P38398-1.2	S1610G	Neutral	0.018
BRCA1	P38398-1.2	S1610H	Neutral	0.039
BRCA1	P38398-1.2	S1610I	Neutral	0.06
BRCA1	P38398-1.2	S1610K	Neutral	0.039
BRCA1	P38398-1.2	S1610L	Neutral	0.06
BRCA1	P38398-1.2	S1610M	Neutral	0.043
BRCA1	P38398-1.2	S1610N	Neutral	0.012
BRCA1	P38398-1.2	S1610P	Neutral	0.021
BRCA1	P38398-1.2	S1610Q	Neutral	0.025
BRCA1	P38398-1.2	S1610R	Neutral	0.072
BRCA1	P38398-1.2	S1610T	Neutral	0.011
BRCA1	P38398-1.2	S1610V	Neutral	0.041
BRCA1	P38398-1.2	S1610W	Neutral	0.179
BRCA1	P38398-1.2	S1610Y	Neutral	0.087
BRCA1	P38398-1.2	A1611C	Neutral	0.035
BRCA1	P38398-1.2	A1611D	Neutral	0.077
BRCA1	P38398-1.2	A1611E	Neutral	0.08
BRCA1	P38398-1.2	A1611F	Neutral	0.18
BRCA1	P38398-1.2	A1611G	Neutral	0.035
BRCA1	P38398-1.2	A1611H	Neutral	0.134
BRCA1	P38398-1.2	A1611I	Neutral	0.107
BRCA1	P38398-1.2	A1611K	Neutral	0.133
BRCA1	P38398-1.2	A1611L	Neutral	0.107
BRCA1	P38398-1.2	A1611M	Neutral	0.108
BRCA1	P38398-1.2	A1611N	Neutral	0.086
BRCA1	P38398-1.2	A1611P	Neutral	0.054
BRCA1	P38398-1.2	A1611Q	Neutral	0.089
BRCA1	P38398-1.2	A1611R	Neutral	0.17
BRCA1	P38398-1.2	A1611S	Neutral	0.019
BRCA1	P38398-1.2	A1611T	Neutral	0.041
BRCA1	P38398-1.2	A1611V	Neutral	0.052
BRCA1	P38398-1.2	A1611W	Neutral	0.369
BRCA1	P38398-1.2	A1611Y	Neutral	0.203
BRCA1	P38398-1.2	Q1612A	Neutral	0.002
BRCA1	P38398-1.2	Q1612C	Neutral	0.002
BRCA1	P38398-1.2	Q1612D	Neutral	0.001
BRCA1	P38398-1.2	Q1612E	Neutral	0.0
BRCA1	P38398-1.2	Q1612F	Neutral	0.002
BRCA1	P38398-1.2	Q1612G	Neutral	0.004
BRCA1	P38398-1.2	Q1612H	Neutral	0.0
BRCA1	P38398-1.2	Q1612I	Neutral	0.002
BRCA1	P38398-1.2	Q1612K	Neutral	0.0
BRCA1	P38398-1.2	Q1612L	Neutral	0.001
BRCA1	P38398-1.2	Q1612M	Neutral	0.001
BRCA1	P38398-1.2	Q1612N	Neutral	0.001
BRCA1	P38398-1.2	Q1612P	Neutral	0.001
BRCA1	P38398-1.2	Q1612R	Neutral	0.001
BRCA1	P38398-1.2	Q1612S	Neutral	0.001
BRCA1	P38398-1.2	Q1612T	Neutral	0.001
BRCA1	P38398-1.2	Q1612V	Neutral	0.001
BRCA1	P38398-1.2	Q1612W	Neutral	0.003
BRCA1	P38398-1.2	Q1612Y	Neutral	0.001
BRCA1	P38398-1.2	S1613A	Neutral	0.016
BRCA1	P38398-1.2	S1613C	Neutral	0.037
BRCA1	P38398-1.2	S1613D	Neutral	0.03
BRCA1	P38398-1.2	S1613E	Neutral	0.043
BRCA1	P38398-1.2	S1613F	Neutral	0.141
BRCA1	P38398-1.2	S1613G	Neutral	0.035
BRCA1	P38398-1.2	S1613H	Neutral	0.075
BRCA1	P38398-1.2	S1613I	Neutral	0.114
BRCA1	P38398-1.2	S1613K	Neutral	0.074
BRCA1	P38398-1.2	S1613L	Neutral	0.114
BRCA1	P38398-1.2	S1613M	Neutral	0.083
BRCA1	P38398-1.2	S1613N	Neutral	0.023
BRCA1	P38398-1.2	S1613P	Neutral	0.041
BRCA1	P38398-1.2	S1613Q	Neutral	0.049
BRCA1	P38398-1.2	S1613R	Neutral	0.134
BRCA1	P38398-1.2	S1613T	Neutral	0.022
BRCA1	P38398-1.2	S1613V	Neutral	0.078
BRCA1	P38398-1.2	S1613W	Neutral	0.303
BRCA1	P38398-1.2	S1613Y	Neutral	0.16
BRCA1	P38398-1.2	P1614A	Neutral	0.07
BRCA1	P38398-1.2	P1614C	Neutral	0.092
BRCA1	P38398-1.2	P1614D	Neutral	0.043
BRCA1	P38398-1.2	P1614E	Neutral	0.063
BRCA1	P38398-1.2	P1614F	Neutral	0.264
BRCA1	P38398-1.2	P1614G	Neutral	0.14
BRCA1	P38398-1.2	P1614H	Neutral	0.107
BRCA1	P38398-1.2	P1614I	Neutral	0.163
BRCA1	P38398-1.2	P1614K	Neutral	0.106
BRCA1	P38398-1.2	P1614L	Neutral	0.164
BRCA1	P38398-1.2	P1614M	Neutral	0.121
BRCA1	P38398-1.2	P1614N	Neutral	0.068
BRCA1	P38398-1.2	P1614Q	Neutral	0.07
BRCA1	P38398-1.2	P1614R	Neutral	0.186
BRCA1	P38398-1.2	P1614S	Neutral	0.061
BRCA1	P38398-1.2	P1614T	Neutral	0.046
BRCA1	P38398-1.2	P1614V	Neutral	0.083
BRCA1	P38398-1.2	P1614W	Neutral	0.399
BRCA1	P38398-1.2	P1614Y	Neutral	0.225
BRCA1	P38398-1.2	A1615C	Neutral	0.256
BRCA1	P38398-1.2	A1615D	Neutral	0.441
BRCA1	P38398-1.2	A1615E	Neutral	0.451
BRCA1	P38398-1.2	A1615F	Pathogenic	0.676
BRCA1	P38398-1.2	A1615G	Neutral	0.257
BRCA1	P38398-1.2	A1615H	Pathogenic	0.594
BRCA1	P38398-1.2	A1615I	Pathogenic	0.531
BRCA1	P38398-1.2	A1615K	Pathogenic	0.592
BRCA1	P38398-1.2	A1615L	Pathogenic	0.532
BRCA1	P38398-1.2	A1615M	Pathogenic	0.534
BRCA1	P38398-1.2	A1615N	Neutral	0.47
BRCA1	P38398-1.2	A1615P	Neutral	0.352
BRCA1	P38398-1.2	A1615Q	Neutral	0.481
BRCA1	P38398-1.2	A1615R	Pathogenic	0.66
BRCA1	P38398-1.2	A1615S	Neutral	0.153
BRCA1	P38398-1.2	A1615T	Neutral	0.289
BRCA1	P38398-1.2	A1615V	Neutral	0.343
BRCA1	P38398-1.2	A1615W	Pathogenic	0.847
BRCA1	P38398-1.2	A1615Y	Pathogenic	0.708
BRCA1	P38398-1.2	A1616C	Neutral	0.038
BRCA1	P38398-1.2	A1616D	Neutral	0.084
BRCA1	P38398-1.2	A1616E	Neutral	0.087
BRCA1	P38398-1.2	A1616F	Neutral	0.194
BRCA1	P38398-1.2	A1616G	Neutral	0.038
BRCA1	P38398-1.2	A1616H	Neutral	0.145
BRCA1	P38398-1.2	A1616I	Neutral	0.116
BRCA1	P38398-1.2	A1616K	Neutral	0.144
BRCA1	P38398-1.2	A1616L	Neutral	0.116
BRCA1	P38398-1.2	A1616M	Neutral	0.117
BRCA1	P38398-1.2	A1616N	Neutral	0.093
BRCA1	P38398-1.2	A1616P	Neutral	0.059
BRCA1	P38398-1.2	A1616Q	Neutral	0.097
BRCA1	P38398-1.2	A1616R	Neutral	0.183
BRCA1	P38398-1.2	A1616S	Neutral	0.02
BRCA1	P38398-1.2	A1616T	Neutral	0.045
BRCA1	P38398-1.2	A1616V	Neutral	0.057
BRCA1	P38398-1.2	A1616W	Neutral	0.39
BRCA1	P38398-1.2	A1616Y	Neutral	0.218
BRCA1	P38398-1.2	A1617C	Neutral	0.023
BRCA1	P38398-1.2	A1617D	Neutral	0.05
BRCA1	P38398-1.2	A1617E	Neutral	0.052
BRCA1	P38398-1.2	A1617F	Neutral	0.123
BRCA1	P38398-1.2	A1617G	Neutral	0.023
BRCA1	P38398-1.2	A1617H	Neutral	0.09
BRCA1	P38398-1.2	A1617I	Neutral	0.071
BRCA1	P38398-1.2	A1617K	Neutral	0.089
BRCA1	P38398-1.2	A1617L	Neutral	0.071
BRCA1	P38398-1.2	A1617M	Neutral	0.071
BRCA1	P38398-1.2	A1617N	Neutral	0.056
BRCA1	P38398-1.2	A1617P	Neutral	0.035
BRCA1	P38398-1.2	A1617Q	Neutral	0.058
BRCA1	P38398-1.2	A1617R	Neutral	0.115
BRCA1	P38398-1.2	A1617S	Neutral	0.012
BRCA1	P38398-1.2	A1617T	Neutral	0.027
BRCA1	P38398-1.2	A1617V	Neutral	0.034
BRCA1	P38398-1.2	A1617W	Neutral	0.271
BRCA1	P38398-1.2	A1617Y	Neutral	0.14
BRCA1	P38398-1.2	H1618A	Neutral	0.098
BRCA1	P38398-1.2	H1618C	Neutral	0.092
BRCA1	P38398-1.2	H1618D	Neutral	0.042
BRCA1	P38398-1.2	H1618E	Neutral	0.02
BRCA1	P38398-1.2	H1618F	Neutral	0.033
BRCA1	P38398-1.2	H1618G	Neutral	0.142
BRCA1	P38398-1.2	H1618I	Neutral	0.053
BRCA1	P38398-1.2	H1618K	Neutral	0.034
BRCA1	P38398-1.2	H1618L	Neutral	0.053
BRCA1	P38398-1.2	H1618M	Neutral	0.038
BRCA1	P38398-1.2	H1618N	Neutral	0.019
BRCA1	P38398-1.2	H1618P	Neutral	0.061
BRCA1	P38398-1.2	H1618Q	Neutral	0.018
BRCA1	P38398-1.2	H1618R	Neutral	0.031
BRCA1	P38398-1.2	H1618S	Neutral	0.062
BRCA1	P38398-1.2	H1618T	Neutral	0.058
BRCA1	P38398-1.2	H1618V	Neutral	0.062
BRCA1	P38398-1.2	H1618W	Neutral	0.084
BRCA1	P38398-1.2	H1618Y	Neutral	0.013
BRCA1	P38398-1.2	T1619A	Neutral	0.017
BRCA1	P38398-1.2	T1619C	Neutral	0.016
BRCA1	P38398-1.2	T1619D	Neutral	0.014
BRCA1	P38398-1.2	T1619E	Neutral	0.019
BRCA1	P38398-1.2	T1619F	Neutral	0.048
BRCA1	P38398-1.2	T1619G	Neutral	0.052
BRCA1	P38398-1.2	T1619H	Neutral	0.034
BRCA1	P38398-1.2	T1619I	Neutral	0.026
BRCA1	P38398-1.2	T1619K	Neutral	0.034
BRCA1	P38398-1.2	T1619L	Neutral	0.026
BRCA1	P38398-1.2	T1619M	Neutral	0.027
BRCA1	P38398-1.2	T1619N	Neutral	0.01
BRCA1	P38398-1.2	T1619P	Neutral	0.015
BRCA1	P38398-1.2	T1619Q	Neutral	0.022
BRCA1	P38398-1.2	T1619R	Neutral	0.044
BRCA1	P38398-1.2	T1619S	Neutral	0.01
BRCA1	P38398-1.2	T1619V	Neutral	0.012
BRCA1	P38398-1.2	T1619W	Neutral	0.084
BRCA1	P38398-1.2	T1619Y	Neutral	0.055
BRCA1	P38398-1.2	T1620A	Neutral	0.013
BRCA1	P38398-1.2	T1620C	Neutral	0.012
BRCA1	P38398-1.2	T1620D	Neutral	0.011
BRCA1	P38398-1.2	T1620E	Neutral	0.014
BRCA1	P38398-1.2	T1620F	Neutral	0.036
BRCA1	P38398-1.2	T1620G	Neutral	0.039
BRCA1	P38398-1.2	T1620H	Neutral	0.025
BRCA1	P38398-1.2	T1620I	Neutral	0.02
BRCA1	P38398-1.2	T1620K	Neutral	0.025
BRCA1	P38398-1.2	T1620L	Neutral	0.02
BRCA1	P38398-1.2	T1620M	Neutral	0.02
BRCA1	P38398-1.2	T1620N	Neutral	0.008
BRCA1	P38398-1.2	T1620P	Neutral	0.011
BRCA1	P38398-1.2	T1620Q	Neutral	0.016
BRCA1	P38398-1.2	T1620R	Neutral	0.033
BRCA1	P38398-1.2	T1620S	Neutral	0.008
BRCA1	P38398-1.2	T1620V	Neutral	0.009
BRCA1	P38398-1.2	T1620W	Neutral	0.064
BRCA1	P38398-1.2	T1620Y	Neutral	0.041
BRCA1	P38398-1.2	D1621A	Neutral	0.015
BRCA1	P38398-1.2	D1621C	Neutral	0.014
BRCA1	P38398-1.2	D1621E	Neutral	0.003
BRCA1	P38398-1.2	D1621F	Neutral	0.031
BRCA1	P38398-1.2	D1621G	Neutral	0.015
BRCA1	P38398-1.2	D1621H	Neutral	0.011
BRCA1	P38398-1.2	D1621I	Neutral	0.025
BRCA1	P38398-1.2	D1621K	Neutral	0.016
BRCA1	P38398-1.2	D1621L	Neutral	0.035
BRCA1	P38398-1.2	D1621M	Neutral	0.025
BRCA1	P38398-1.2	D1621N	Neutral	0.003
BRCA1	P38398-1.2	D1621P	Neutral	0.006
BRCA1	P38398-1.2	D1621Q	Neutral	0.007
BRCA1	P38398-1.2	D1621R	Neutral	0.03
BRCA1	P38398-1.2	D1621S	Neutral	0.006
BRCA1	P38398-1.2	D1621T	Neutral	0.006
BRCA1	P38398-1.2	D1621V	Neutral	0.016
BRCA1	P38398-1.2	D1621W	Neutral	0.079
BRCA1	P38398-1.2	D1621Y	Neutral	0.036
BRCA1	P38398-1.2	T1622A	Neutral	0.011
BRCA1	P38398-1.2	T1622C	Neutral	0.01
BRCA1	P38398-1.2	T1622D	Neutral	0.009
BRCA1	P38398-1.2	T1622E	Neutral	0.012
BRCA1	P38398-1.2	T1622F	Neutral	0.03
BRCA1	P38398-1.2	T1622G	Neutral	0.033
BRCA1	P38398-1.2	T1622H	Neutral	0.021
BRCA1	P38398-1.2	T1622I	Neutral	0.016
BRCA1	P38398-1.2	T1622K	Neutral	0.021
BRCA1	P38398-1.2	T1622L	Neutral	0.017
BRCA1	P38398-1.2	T1622M	Neutral	0.017
BRCA1	P38398-1.2	T1622N	Neutral	0.006
BRCA1	P38398-1.2	T1622P	Neutral	0.009
BRCA1	P38398-1.2	T1622Q	Neutral	0.014
BRCA1	P38398-1.2	T1622R	Neutral	0.028
BRCA1	P38398-1.2	T1622S	Neutral	0.006
BRCA1	P38398-1.2	T1622V	Neutral	0.008
BRCA1	P38398-1.2	T1622W	Neutral	0.054
BRCA1	P38398-1.2	T1622Y	Neutral	0.035
BRCA1	P38398-1.2	A1623C	Neutral	0.043
BRCA1	P38398-1.2	A1623D	Neutral	0.094
BRCA1	P38398-1.2	A1623E	Neutral	0.098
BRCA1	P38398-1.2	A1623F	Neutral	0.216
BRCA1	P38398-1.2	A1623G	Neutral	0.044
BRCA1	P38398-1.2	A1623H	Neutral	0.162
BRCA1	P38398-1.2	A1623I	Neutral	0.13
BRCA1	P38398-1.2	A1623K	Neutral	0.161
BRCA1	P38398-1.2	A1623L	Neutral	0.13
BRCA1	P38398-1.2	A1623M	Neutral	0.131
BRCA1	P38398-1.2	A1623N	Neutral	0.105
BRCA1	P38398-1.2	A1623P	Neutral	0.067
BRCA1	P38398-1.2	A1623Q	Neutral	0.109
BRCA1	P38398-1.2	A1623R	Neutral	0.204
BRCA1	P38398-1.2	A1623S	Neutral	0.023
BRCA1	P38398-1.2	A1623T	Neutral	0.051
BRCA1	P38398-1.2	A1623V	Neutral	0.065
BRCA1	P38398-1.2	A1623W	Neutral	0.422
BRCA1	P38398-1.2	A1623Y	Neutral	0.242
BRCA1	P38398-1.2	G1624A	Neutral	0.042
BRCA1	P38398-1.2	G1624C	Neutral	0.163
BRCA1	P38398-1.2	G1624D	Neutral	0.096
BRCA1	P38398-1.2	G1624E	Neutral	0.185
BRCA1	P38398-1.2	G1624F	Neutral	0.363
BRCA1	P38398-1.2	G1624H	Neutral	0.219
BRCA1	P38398-1.2	G1624I	Neutral	0.391
BRCA1	P38398-1.2	G1624K	Neutral	0.287
BRCA1	P38398-1.2	G1624L	Neutral	0.392
BRCA1	P38398-1.2	G1624M	Neutral	0.311
BRCA1	P38398-1.2	G1624N	Neutral	0.076
BRCA1	P38398-1.2	G1624P	Neutral	0.13
BRCA1	P38398-1.2	G1624Q	Neutral	0.204
BRCA1	P38398-1.2	G1624R	Neutral	0.35
BRCA1	P38398-1.2	G1624S	Neutral	0.048
BRCA1	P38398-1.2	G1624T	Neutral	0.138
BRCA1	P38398-1.2	G1624V	Neutral	0.229
BRCA1	P38398-1.2	G1624W	Neutral	0.423
BRCA1	P38398-1.2	G1624Y	Neutral	0.398
BRCA1	P38398-1.2	Y1625A	Neutral	0.07
BRCA1	P38398-1.2	Y1625C	Neutral	0.048
BRCA1	P38398-1.2	Y1625D	Neutral	0.059
BRCA1	P38398-1.2	Y1625E	Neutral	0.028
BRCA1	P38398-1.2	Y1625F	Neutral	0.003
BRCA1	P38398-1.2	Y1625G	Neutral	0.141
BRCA1	P38398-1.2	Y1625H	Neutral	0.006
BRCA1	P38398-1.2	Y1625I	Neutral	0.014
BRCA1	P38398-1.2	Y1625K	Neutral	0.016
BRCA1	P38398-1.2	Y1625L	Neutral	0.015
BRCA1	P38398-1.2	Y1625M	Neutral	0.015
BRCA1	P38398-1.2	Y1625N	Neutral	0.037
BRCA1	P38398-1.2	Y1625P	Neutral	0.062
BRCA1	P38398-1.2	Y1625Q	Neutral	0.018
BRCA1	P38398-1.2	Y1625R	Neutral	0.016
BRCA1	P38398-1.2	Y1625S	Neutral	0.061
BRCA1	P38398-1.2	Y1625T	Neutral	0.041
BRCA1	P38398-1.2	Y1625V	Neutral	0.022
BRCA1	P38398-1.2	Y1625W	Neutral	0.005
BRCA1	P38398-1.2	N1626A	Neutral	0.01
BRCA1	P38398-1.2	N1626C	Neutral	0.009
BRCA1	P38398-1.2	N1626D	Neutral	0.002
BRCA1	P38398-1.2	N1626E	Neutral	0.003
BRCA1	P38398-1.2	N1626F	Neutral	0.017
BRCA1	P38398-1.2	N1626G	Neutral	0.007
BRCA1	P38398-1.2	N1626H	Neutral	0.003
BRCA1	P38398-1.2	N1626I	Neutral	0.013
BRCA1	P38398-1.2	N1626K	Neutral	0.006
BRCA1	P38398-1.2	N1626L	Neutral	0.013
BRCA1	P38398-1.2	N1626M	Neutral	0.009
BRCA1	P38398-1.2	N1626P	Neutral	0.006
BRCA1	P38398-1.2	N1626Q	Neutral	0.004
BRCA1	P38398-1.2	N1626R	Neutral	0.008
BRCA1	P38398-1.2	N1626S	Neutral	0.003
BRCA1	P38398-1.2	N1626T	Neutral	0.003
BRCA1	P38398-1.2	N1626V	Neutral	0.009
BRCA1	P38398-1.2	N1626W	Neutral	0.044
BRCA1	P38398-1.2	N1626Y	Neutral	0.014
BRCA1	P38398-1.2	A1627C	Neutral	0.003
BRCA1	P38398-1.2	A1627D	Neutral	0.006
BRCA1	P38398-1.2	A1627E	Neutral	0.006
BRCA1	P38398-1.2	A1627F	Neutral	0.015
BRCA1	P38398-1.2	A1627G	Neutral	0.003
BRCA1	P38398-1.2	A1627H	Neutral	0.011
BRCA1	P38398-1.2	A1627I	Neutral	0.008
BRCA1	P38398-1.2	A1627K	Neutral	0.011
BRCA1	P38398-1.2	A1627L	Neutral	0.008
BRCA1	P38398-1.2	A1627M	Neutral	0.008
BRCA1	P38398-1.2	A1627N	Neutral	0.006
BRCA1	P38398-1.2	A1627P	Neutral	0.004
BRCA1	P38398-1.2	A1627Q	Neutral	0.007
BRCA1	P38398-1.2	A1627R	Neutral	0.014
BRCA1	P38398-1.2	A1627S	Neutral	0.001
BRCA1	P38398-1.2	A1627T	Neutral	0.003
BRCA1	P38398-1.2	A1627V	Neutral	0.004
BRCA1	P38398-1.2	A1627W	Neutral	0.039
BRCA1	P38398-1.2	A1627Y	Neutral	0.017
BRCA1	P38398-1.2	M1628A	Neutral	0.031
BRCA1	P38398-1.2	M1628C	Neutral	0.02
BRCA1	P38398-1.2	M1628D	Neutral	0.036
BRCA1	P38398-1.2	M1628E	Neutral	0.017
BRCA1	P38398-1.2	M1628F	Neutral	0.008
BRCA1	P38398-1.2	M1628G	Neutral	0.09
BRCA1	P38398-1.2	M1628H	Neutral	0.014
BRCA1	P38398-1.2	M1628I	Neutral	0.004
BRCA1	P38398-1.2	M1628K	Neutral	0.011
BRCA1	P38398-1.2	M1628L	Neutral	0.003
BRCA1	P38398-1.2	M1628N	Neutral	0.023
BRCA1	P38398-1.2	M1628P	Neutral	0.027
BRCA1	P38398-1.2	M1628Q	Neutral	0.008
BRCA1	P38398-1.2	M1628R	Neutral	0.015
BRCA1	P38398-1.2	M1628S	Neutral	0.027
BRCA1	P38398-1.2	M1628T	Neutral	0.017
BRCA1	P38398-1.2	M1628V	Neutral	0.007
BRCA1	P38398-1.2	M1628W	Neutral	0.021
BRCA1	P38398-1.2	M1628Y	Neutral	0.013
BRCA1	P38398-1.2	E1629A	Neutral	0.18
BRCA1	P38398-1.2	E1629C	Neutral	0.298
BRCA1	P38398-1.2	E1629D	Neutral	0.042
BRCA1	P38398-1.2	E1629F	Neutral	0.237
BRCA1	P38398-1.2	E1629G	Neutral	0.327
BRCA1	P38398-1.2	E1629H	Neutral	0.069
BRCA1	P38398-1.2	E1629I	Neutral	0.195
BRCA1	P38398-1.2	E1629K	Neutral	0.07
BRCA1	P38398-1.2	E1629L	Neutral	0.196
BRCA1	P38398-1.2	E1629M	Neutral	0.146
BRCA1	P38398-1.2	E1629N	Neutral	0.075
BRCA1	P38398-1.2	E1629P	Neutral	0.116
BRCA1	P38398-1.2	E1629Q	Neutral	0.032
BRCA1	P38398-1.2	E1629R	Neutral	0.126
BRCA1	P38398-1.2	E1629S	Neutral	0.119
BRCA1	P38398-1.2	E1629T	Neutral	0.11
BRCA1	P38398-1.2	E1629V	Neutral	0.118
BRCA1	P38398-1.2	E1629W	Neutral	0.364
BRCA1	P38398-1.2	E1629Y	Neutral	0.2
BRCA1	P38398-1.2	E1630A	Neutral	0.064
BRCA1	P38398-1.2	E1630C	Neutral	0.116
BRCA1	P38398-1.2	E1630D	Neutral	0.013
BRCA1	P38398-1.2	E1630F	Neutral	0.088
BRCA1	P38398-1.2	E1630G	Neutral	0.131
BRCA1	P38398-1.2	E1630H	Neutral	0.022
BRCA1	P38398-1.2	E1630I	Neutral	0.07
BRCA1	P38398-1.2	E1630K	Neutral	0.023
BRCA1	P38398-1.2	E1630L	Neutral	0.07
BRCA1	P38398-1.2	E1630M	Neutral	0.05
BRCA1	P38398-1.2	E1630N	Neutral	0.025
BRCA1	P38398-1.2	E1630P	Neutral	0.039
BRCA1	P38398-1.2	E1630Q	Neutral	0.01
BRCA1	P38398-1.2	E1630R	Neutral	0.043
BRCA1	P38398-1.2	E1630S	Neutral	0.04
BRCA1	P38398-1.2	E1630T	Neutral	0.037
BRCA1	P38398-1.2	E1630V	Neutral	0.04
BRCA1	P38398-1.2	E1630W	Neutral	0.151
BRCA1	P38398-1.2	E1630Y	Neutral	0.072
BRCA1	P38398-1.2	S1631A	Neutral	0.003
BRCA1	P38398-1.2	S1631C	Neutral	0.008
BRCA1	P38398-1.2	S1631D	Neutral	0.006
BRCA1	P38398-1.2	S1631E	Neutral	0.009
BRCA1	P38398-1.2	S1631F	Neutral	0.031
BRCA1	P38398-1.2	S1631G	Neutral	0.007
BRCA1	P38398-1.2	S1631H	Neutral	0.016
BRCA1	P38398-1.2	S1631I	Neutral	0.025
BRCA1	P38398-1.2	S1631K	Neutral	0.016
BRCA1	P38398-1.2	S1631L	Neutral	0.025
BRCA1	P38398-1.2	S1631M	Neutral	0.017
BRCA1	P38398-1.2	S1631N	Neutral	0.005
BRCA1	P38398-1.2	S1631P	Neutral	0.008
BRCA1	P38398-1.2	S1631Q	Neutral	0.01
BRCA1	P38398-1.2	S1631R	Neutral	0.029
BRCA1	P38398-1.2	S1631T	Neutral	0.004
BRCA1	P38398-1.2	S1631V	Neutral	0.016
BRCA1	P38398-1.2	S1631W	Neutral	0.079
BRCA1	P38398-1.2	S1631Y	Neutral	0.036
BRCA1	P38398-1.2	V1632A	Neutral	0.039
BRCA1	P38398-1.2	V1632C	Neutral	0.038
BRCA1	P38398-1.2	V1632D	Neutral	0.065
BRCA1	P38398-1.2	V1632E	Neutral	0.038
BRCA1	P38398-1.2	V1632F	Neutral	0.047
BRCA1	P38398-1.2	V1632G	Neutral	0.156
BRCA1	P38398-1.2	V1632H	Neutral	0.065
BRCA1	P38398-1.2	V1632I	Neutral	0.009
BRCA1	P38398-1.2	V1632K	Neutral	0.065
BRCA1	P38398-1.2	V1632L	Neutral	0.018
BRCA1	P38398-1.2	V1632M	Neutral	0.019
BRCA1	P38398-1.2	V1632N	Neutral	0.059
BRCA1	P38398-1.2	V1632P	Neutral	0.049
BRCA1	P38398-1.2	V1632Q	Neutral	0.042
BRCA1	P38398-1.2	V1632R	Neutral	0.117
BRCA1	P38398-1.2	V1632S	Neutral	0.069
BRCA1	P38398-1.2	V1632T	Neutral	0.022
BRCA1	P38398-1.2	V1632W	Neutral	0.159
BRCA1	P38398-1.2	V1632Y	Neutral	0.054
BRCA1	P38398-1.2	S1633A	Neutral	0.071
BRCA1	P38398-1.2	S1633C	Neutral	0.155
BRCA1	P38398-1.2	S1633D	Neutral	0.125
BRCA1	P38398-1.2	S1633E	Neutral	0.176
BRCA1	P38398-1.2	S1633F	Neutral	0.436
BRCA1	P38398-1.2	S1633G	Neutral	0.145
BRCA1	P38398-1.2	S1633H	Neutral	0.275
BRCA1	P38398-1.2	S1633I	Neutral	0.377
BRCA1	P38398-1.2	S1633K	Neutral	0.275
BRCA1	P38398-1.2	S1633L	Neutral	0.377
BRCA1	P38398-1.2	S1633M	Neutral	0.298
BRCA1	P38398-1.2	S1633N	Neutral	0.1
BRCA1	P38398-1.2	S1633P	Neutral	0.168
BRCA1	P38398-1.2	S1633Q	Neutral	0.194
BRCA1	P38398-1.2	S1633R	Neutral	0.421
BRCA1	P38398-1.2	S1633T	Neutral	0.095
BRCA1	P38398-1.2	S1633V	Neutral	0.286
BRCA1	P38398-1.2	S1633W	Pathogenic	0.672
BRCA1	P38398-1.2	S1633Y	Neutral	0.473
BRCA1	P38398-1.2	R1634A	Neutral	0.092
BRCA1	P38398-1.2	R1634C	Neutral	0.119
BRCA1	P38398-1.2	R1634D	Neutral	0.08
BRCA1	P38398-1.2	R1634E	Neutral	0.027
BRCA1	P38398-1.2	R1634F	Neutral	0.043
BRCA1	P38398-1.2	R1634G	Neutral	0.183
BRCA1	P38398-1.2	R1634H	Neutral	0.022
BRCA1	P38398-1.2	R1634I	Neutral	0.054
BRCA1	P38398-1.2	R1634K	Neutral	0.008
BRCA1	P38398-1.2	R1634L	Neutral	0.038
BRCA1	P38398-1.2	R1634M	Neutral	0.027
BRCA1	P38398-1.2	R1634N	Neutral	0.036
BRCA1	P38398-1.2	R1634P	Neutral	0.08
BRCA1	P38398-1.2	R1634Q	Neutral	0.017
BRCA1	P38398-1.2	R1634S	Neutral	0.082
BRCA1	P38398-1.2	R1634T	Neutral	0.054
BRCA1	P38398-1.2	R1634V	Neutral	0.081
BRCA1	P38398-1.2	R1634W	Neutral	0.045
BRCA1	P38398-1.2	R1634Y	Neutral	0.027
BRCA1	P38398-1.2	E1635A	Neutral	0.011
BRCA1	P38398-1.2	E1635C	Neutral	0.021
BRCA1	P38398-1.2	E1635D	Neutral	0.002
BRCA1	P38398-1.2	E1635F	Neutral	0.016
BRCA1	P38398-1.2	E1635G	Neutral	0.025
BRCA1	P38398-1.2	E1635H	Neutral	0.004
BRCA1	P38398-1.2	E1635I	Neutral	0.012
BRCA1	P38398-1.2	E1635K	Neutral	0.004
BRCA1	P38398-1.2	E1635L	Neutral	0.012
BRCA1	P38398-1.2	E1635M	Neutral	0.009
BRCA1	P38398-1.2	E1635N	Neutral	0.004
BRCA1	P38398-1.2	E1635P	Neutral	0.007
BRCA1	P38398-1.2	E1635Q	Neutral	0.002
BRCA1	P38398-1.2	E1635R	Neutral	0.007
BRCA1	P38398-1.2	E1635S	Neutral	0.007
BRCA1	P38398-1.2	E1635T	Neutral	0.006
BRCA1	P38398-1.2	E1635V	Neutral	0.007
BRCA1	P38398-1.2	E1635W	Neutral	0.029
BRCA1	P38398-1.2	E1635Y	Neutral	0.013
BRCA1	P38398-1.2	K1636A	Neutral	0.125
BRCA1	P38398-1.2	K1636C	Neutral	0.161
BRCA1	P38398-1.2	K1636D	Neutral	0.079
BRCA1	P38398-1.2	K1636E	Neutral	0.027
BRCA1	P38398-1.2	K1636F	Neutral	0.06
BRCA1	P38398-1.2	K1636G	Neutral	0.24
BRCA1	P38398-1.2	K1636H	Neutral	0.044
BRCA1	P38398-1.2	K1636I	Neutral	0.075
BRCA1	P38398-1.2	K1636L	Neutral	0.053
BRCA1	P38398-1.2	K1636M	Neutral	0.038
BRCA1	P38398-1.2	K1636N	Neutral	0.05
BRCA1	P38398-1.2	K1636P	Neutral	0.078
BRCA1	P38398-1.2	K1636Q	Neutral	0.024
BRCA1	P38398-1.2	K1636R	Neutral	0.014
BRCA1	P38398-1.2	K1636S	Neutral	0.08
BRCA1	P38398-1.2	K1636T	Neutral	0.074
BRCA1	P38398-1.2	K1636V	Neutral	0.08
BRCA1	P38398-1.2	K1636W	Neutral	0.105
BRCA1	P38398-1.2	K1636Y	Neutral	0.049
BRCA1	P38398-1.2	P1637A	Neutral	0.369
BRCA1	P38398-1.2	P1637C	Neutral	0.443
BRCA1	P38398-1.2	P1637D	Neutral	0.26
BRCA1	P38398-1.2	P1637E	Neutral	0.344
BRCA1	P38398-1.2	P1637F	Pathogenic	0.737
BRCA1	P38398-1.2	P1637G	Pathogenic	0.56
BRCA1	P38398-1.2	P1637H	Neutral	0.484
BRCA1	P38398-1.2	P1637I	Pathogenic	0.604
BRCA1	P38398-1.2	P1637K	Neutral	0.482
BRCA1	P38398-1.2	P1637L	Pathogenic	0.604
BRCA1	P38398-1.2	P1637M	Pathogenic	0.517
BRCA1	P38398-1.2	P1637N	Neutral	0.362
BRCA1	P38398-1.2	P1637Q	Neutral	0.372
BRCA1	P38398-1.2	P1637R	Pathogenic	0.641
BRCA1	P38398-1.2	P1637S	Neutral	0.337
BRCA1	P38398-1.2	P1637T	Neutral	0.272
BRCA1	P38398-1.2	P1637V	Neutral	0.413
BRCA1	P38398-1.2	P1637W	Pathogenic	0.838
BRCA1	P38398-1.2	P1637Y	Pathogenic	0.693
BRCA1	P38398-1.2	E1638A	Neutral	0.092
BRCA1	P38398-1.2	E1638C	Neutral	0.163
BRCA1	P38398-1.2	E1638D	Neutral	0.02
BRCA1	P38398-1.2	E1638F	Neutral	0.125
BRCA1	P38398-1.2	E1638G	Neutral	0.182
BRCA1	P38398-1.2	E1638H	Neutral	0.033
BRCA1	P38398-1.2	E1638I	Neutral	0.1
BRCA1	P38398-1.2	E1638K	Neutral	0.033
BRCA1	P38398-1.2	E1638L	Neutral	0.1
BRCA1	P38398-1.2	E1638M	Neutral	0.073
BRCA1	P38398-1.2	E1638N	Neutral	0.036
BRCA1	P38398-1.2	E1638P	Neutral	0.057
BRCA1	P38398-1.2	E1638Q	Neutral	0.015
BRCA1	P38398-1.2	E1638R	Neutral	0.062
BRCA1	P38398-1.2	E1638S	Neutral	0.058
BRCA1	P38398-1.2	E1638T	Neutral	0.054
BRCA1	P38398-1.2	E1638V	Neutral	0.058
BRCA1	P38398-1.2	E1638W	Neutral	0.208
BRCA1	P38398-1.2	E1638Y	Neutral	0.103
BRCA1	P38398-1.2	L1639A	Neutral	0.009
BRCA1	P38398-1.2	L1639C	Neutral	0.006
BRCA1	P38398-1.2	L1639D	Neutral	0.016
BRCA1	P38398-1.2	L1639E	Neutral	0.007
BRCA1	P38398-1.2	L1639F	Neutral	0.002
BRCA1	P38398-1.2	L1639G	Neutral	0.041
BRCA1	P38398-1.2	L1639H	Neutral	0.006
BRCA1	P38398-1.2	L1639I	Neutral	0.001
BRCA1	P38398-1.2	L1639K	Neutral	0.005
BRCA1	P38398-1.2	L1639M	Neutral	0.001
BRCA1	P38398-1.2	L1639N	Neutral	0.01
BRCA1	P38398-1.2	L1639P	Neutral	0.012
BRCA1	P38398-1.2	L1639Q	Neutral	0.005
BRCA1	P38398-1.2	L1639R	Neutral	0.006
BRCA1	P38398-1.2	L1639S	Neutral	0.012
BRCA1	P38398-1.2	L1639T	Neutral	0.005
BRCA1	P38398-1.2	L1639V	Neutral	0.002
BRCA1	P38398-1.2	L1639W	Neutral	0.009
BRCA1	P38398-1.2	L1639Y	Neutral	0.004
BRCA1	P38398-1.2	T1640A	Neutral	0.007
BRCA1	P38398-1.2	T1640C	Neutral	0.006
BRCA1	P38398-1.2	T1640D	Neutral	0.005
BRCA1	P38398-1.2	T1640E	Neutral	0.007
BRCA1	P38398-1.2	T1640F	Neutral	0.019
BRCA1	P38398-1.2	T1640G	Neutral	0.02
BRCA1	P38398-1.2	T1640H	Neutral	0.013
BRCA1	P38398-1.2	T1640I	Neutral	0.01
BRCA1	P38398-1.2	T1640K	Neutral	0.013
BRCA1	P38398-1.2	T1640L	Neutral	0.01
BRCA1	P38398-1.2	T1640M	Neutral	0.01
BRCA1	P38398-1.2	T1640N	Neutral	0.004
BRCA1	P38398-1.2	T1640P	Neutral	0.006
BRCA1	P38398-1.2	T1640Q	Neutral	0.008
BRCA1	P38398-1.2	T1640R	Neutral	0.017
BRCA1	P38398-1.2	T1640S	Neutral	0.004
BRCA1	P38398-1.2	T1640V	Neutral	0.005
BRCA1	P38398-1.2	T1640W	Neutral	0.034
BRCA1	P38398-1.2	T1640Y	Neutral	0.021
BRCA1	P38398-1.2	A1641C	Neutral	0.045
BRCA1	P38398-1.2	A1641D	Neutral	0.097
BRCA1	P38398-1.2	A1641E	Neutral	0.1
BRCA1	P38398-1.2	A1641F	Neutral	0.22
BRCA1	P38398-1.2	A1641G	Neutral	0.045
BRCA1	P38398-1.2	A1641H	Neutral	0.166
BRCA1	P38398-1.2	A1641I	Neutral	0.133
BRCA1	P38398-1.2	A1641K	Neutral	0.165
BRCA1	P38398-1.2	A1641L	Neutral	0.133
BRCA1	P38398-1.2	A1641M	Neutral	0.135
BRCA1	P38398-1.2	A1641N	Neutral	0.107
BRCA1	P38398-1.2	A1641P	Neutral	0.069
BRCA1	P38398-1.2	A1641Q	Neutral	0.111
BRCA1	P38398-1.2	A1641R	Neutral	0.208
BRCA1	P38398-1.2	A1641S	Neutral	0.024
BRCA1	P38398-1.2	A1641T	Neutral	0.052
BRCA1	P38398-1.2	A1641V	Neutral	0.066
BRCA1	P38398-1.2	A1641W	Neutral	0.429
BRCA1	P38398-1.2	A1641Y	Neutral	0.247
BRCA1	P38398-1.2	S1642A	Neutral	0.163
BRCA1	P38398-1.2	S1642C	Neutral	0.318
BRCA1	P38398-1.2	S1642D	Neutral	0.267
BRCA1	P38398-1.2	S1642E	Neutral	0.353
BRCA1	P38398-1.2	S1642F	Pathogenic	0.662
BRCA1	P38398-1.2	S1642G	Neutral	0.301
BRCA1	P38398-1.2	S1642H	Neutral	0.491
BRCA1	P38398-1.2	S1642I	Pathogenic	0.606
BRCA1	P38398-1.2	S1642K	Neutral	0.491
BRCA1	P38398-1.2	S1642L	Pathogenic	0.606
BRCA1	P38398-1.2	S1642M	Pathogenic	0.519
BRCA1	P38398-1.2	S1642N	Neutral	0.221
BRCA1	P38398-1.2	S1642P	Neutral	0.339
BRCA1	P38398-1.2	S1642Q	Neutral	0.38
BRCA1	P38398-1.2	S1642R	Pathogenic	0.649
BRCA1	P38398-1.2	S1642T	Neutral	0.211
BRCA1	P38398-1.2	S1642V	Pathogenic	0.505
BRCA1	P38398-1.2	S1642W	Pathogenic	0.839
BRCA1	P38398-1.2	S1642Y	Pathogenic	0.695
BRCA1	P38398-1.2	T1643A	Neutral	0.014
BRCA1	P38398-1.2	T1643C	Neutral	0.013
BRCA1	P38398-1.2	T1643D	Neutral	0.011
BRCA1	P38398-1.2	T1643E	Neutral	0.016
BRCA1	P38398-1.2	T1643F	Neutral	0.039
BRCA1	P38398-1.2	T1643G	Neutral	0.042
BRCA1	P38398-1.2	T1643H	Neutral	0.027
BRCA1	P38398-1.2	T1643I	Neutral	0.021
BRCA1	P38398-1.2	T1643K	Neutral	0.027
BRCA1	P38398-1.2	T1643L	Neutral	0.021
BRCA1	P38398-1.2	T1643M	Neutral	0.022
BRCA1	P38398-1.2	T1643N	Neutral	0.008
BRCA1	P38398-1.2	T1643P	Neutral	0.012
BRCA1	P38398-1.2	T1643Q	Neutral	0.018
BRCA1	P38398-1.2	T1643R	Neutral	0.036
BRCA1	P38398-1.2	T1643S	Neutral	0.008
BRCA1	P38398-1.2	T1643V	Neutral	0.01
BRCA1	P38398-1.2	T1643W	Neutral	0.069
BRCA1	P38398-1.2	T1643Y	Neutral	0.044
BRCA1	P38398-1.2	E1644A	Neutral	0.023
BRCA1	P38398-1.2	E1644C	Neutral	0.043
BRCA1	P38398-1.2	E1644D	Neutral	0.005
BRCA1	P38398-1.2	E1644F	Neutral	0.032
BRCA1	P38398-1.2	E1644G	Neutral	0.049
BRCA1	P38398-1.2	E1644H	Neutral	0.008
BRCA1	P38398-1.2	E1644I	Neutral	0.025
BRCA1	P38398-1.2	E1644K	Neutral	0.008
BRCA1	P38398-1.2	E1644L	Neutral	0.025
BRCA1	P38398-1.2	E1644M	Neutral	0.018
BRCA1	P38398-1.2	E1644N	Neutral	0.009
BRCA1	P38398-1.2	E1644P	Neutral	0.014
BRCA1	P38398-1.2	E1644Q	Neutral	0.003
BRCA1	P38398-1.2	E1644R	Neutral	0.015
BRCA1	P38398-1.2	E1644S	Neutral	0.014
BRCA1	P38398-1.2	E1644T	Neutral	0.013
BRCA1	P38398-1.2	E1644V	Neutral	0.014
BRCA1	P38398-1.2	E1644W	Neutral	0.057
BRCA1	P38398-1.2	E1644Y	Neutral	0.026
BRCA1	P38398-1.2	R1645A	Neutral	0.259
BRCA1	P38398-1.2	R1645C	Neutral	0.319
BRCA1	P38398-1.2	R1645D	Neutral	0.232
BRCA1	P38398-1.2	R1645E	Neutral	0.089
BRCA1	P38398-1.2	R1645F	Neutral	0.134
BRCA1	P38398-1.2	R1645G	Neutral	0.436
BRCA1	P38398-1.2	R1645H	Neutral	0.073
BRCA1	P38398-1.2	R1645I	Neutral	0.165
BRCA1	P38398-1.2	R1645K	Neutral	0.026
BRCA1	P38398-1.2	R1645L	Neutral	0.121
BRCA1	P38398-1.2	R1645M	Neutral	0.088
BRCA1	P38398-1.2	R1645N	Neutral	0.115
BRCA1	P38398-1.2	R1645P	Neutral	0.23
BRCA1	P38398-1.2	R1645Q	Neutral	0.057
BRCA1	P38398-1.2	R1645S	Neutral	0.235
BRCA1	P38398-1.2	R1645T	Neutral	0.164
BRCA1	P38398-1.2	R1645V	Neutral	0.234
BRCA1	P38398-1.2	R1645W	Neutral	0.139
BRCA1	P38398-1.2	R1645Y	Neutral	0.088
BRCA1	P38398-1.2	V1646A	Neutral	0.007
BRCA1	P38398-1.2	V1646C	Neutral	0.006
BRCA1	P38398-1.2	V1646D	Neutral	0.011
BRCA1	P38398-1.2	V1646E	Neutral	0.006
BRCA1	P38398-1.2	V1646F	Neutral	0.008
BRCA1	P38398-1.2	V1646G	Neutral	0.03
BRCA1	P38398-1.2	V1646H	Neutral	0.011
BRCA1	P38398-1.2	V1646I	Neutral	0.001
BRCA1	P38398-1.2	V1646K	Neutral	0.011
BRCA1	P38398-1.2	V1646L	Neutral	0.003
BRCA1	P38398-1.2	V1646M	Neutral	0.003
BRCA1	P38398-1.2	V1646N	Neutral	0.01
BRCA1	P38398-1.2	V1646P	Neutral	0.008
BRCA1	P38398-1.2	V1646Q	Neutral	0.007
BRCA1	P38398-1.2	V1646R	Neutral	0.022
BRCA1	P38398-1.2	V1646S	Neutral	0.012
BRCA1	P38398-1.2	V1646T	Neutral	0.004
BRCA1	P38398-1.2	V1646W	Neutral	0.03
BRCA1	P38398-1.2	V1646Y	Neutral	0.009
BRCA1	P38398-1.2	N1647A	Neutral	0.005
BRCA1	P38398-1.2	N1647C	Neutral	0.005
BRCA1	P38398-1.2	N1647D	Neutral	0.001
BRCA1	P38398-1.2	N1647E	Neutral	0.002
BRCA1	P38398-1.2	N1647F	Neutral	0.009
BRCA1	P38398-1.2	N1647G	Neutral	0.004
BRCA1	P38398-1.2	N1647H	Neutral	0.002
BRCA1	P38398-1.2	N1647I	Neutral	0.007
BRCA1	P38398-1.2	N1647K	Neutral	0.003
BRCA1	P38398-1.2	N1647L	Neutral	0.007
BRCA1	P38398-1.2	N1647M	Neutral	0.005
BRCA1	P38398-1.2	N1647P	Neutral	0.003
BRCA1	P38398-1.2	N1647Q	Neutral	0.002
BRCA1	P38398-1.2	N1647R	Neutral	0.004
BRCA1	P38398-1.2	N1647S	Neutral	0.002
BRCA1	P38398-1.2	N1647T	Neutral	0.001
BRCA1	P38398-1.2	N1647V	Neutral	0.005
BRCA1	P38398-1.2	N1647W	Neutral	0.024
BRCA1	P38398-1.2	N1647Y	Neutral	0.007
BRCA1	P38398-1.2	K1648A	Neutral	0.173
BRCA1	P38398-1.2	K1648C	Neutral	0.219
BRCA1	P38398-1.2	K1648D	Neutral	0.111
BRCA1	P38398-1.2	K1648E	Neutral	0.039
BRCA1	P38398-1.2	K1648F	Neutral	0.085
BRCA1	P38398-1.2	K1648G	Neutral	0.316
BRCA1	P38398-1.2	K1648H	Neutral	0.063
BRCA1	P38398-1.2	K1648I	Neutral	0.106
BRCA1	P38398-1.2	K1648L	Neutral	0.076
BRCA1	P38398-1.2	K1648M	Neutral	0.055
BRCA1	P38398-1.2	K1648N	Neutral	0.072
BRCA1	P38398-1.2	K1648P	Neutral	0.111
BRCA1	P38398-1.2	K1648Q	Neutral	0.035
BRCA1	P38398-1.2	K1648R	Neutral	0.021
BRCA1	P38398-1.2	K1648S	Neutral	0.113
BRCA1	P38398-1.2	K1648T	Neutral	0.105
BRCA1	P38398-1.2	K1648V	Neutral	0.113
BRCA1	P38398-1.2	K1648W	Neutral	0.146
BRCA1	P38398-1.2	K1648Y	Neutral	0.07
BRCA1	P38398-1.2	R1649A	Neutral	0.392
BRCA1	P38398-1.2	R1649C	Neutral	0.463
BRCA1	P38398-1.2	R1649D	Neutral	0.357
BRCA1	P38398-1.2	R1649E	Neutral	0.152
BRCA1	P38398-1.2	R1649F	Neutral	0.223
BRCA1	P38398-1.2	R1649G	Pathogenic	0.587
BRCA1	P38398-1.2	R1649H	Neutral	0.126
BRCA1	P38398-1.2	R1649I	Neutral	0.268
BRCA1	P38398-1.2	R1649K	Neutral	0.047
BRCA1	P38398-1.2	R1649L	Neutral	0.203
BRCA1	P38398-1.2	R1649M	Neutral	0.151
BRCA1	P38398-1.2	R1649N	Neutral	0.193
BRCA1	P38398-1.2	R1649P	Neutral	0.356
BRCA1	P38398-1.2	R1649Q	Neutral	0.1
BRCA1	P38398-1.2	R1649S	Neutral	0.362
BRCA1	P38398-1.2	R1649T	Neutral	0.266
BRCA1	P38398-1.2	R1649V	Neutral	0.36
BRCA1	P38398-1.2	R1649W	Neutral	0.229
BRCA1	P38398-1.2	R1649Y	Neutral	0.15
BRCA1	P38398-1.2	M1650A	Neutral	0.047
BRCA1	P38398-1.2	M1650C	Neutral	0.032
BRCA1	P38398-1.2	M1650D	Neutral	0.056
BRCA1	P38398-1.2	M1650E	Neutral	0.027
BRCA1	P38398-1.2	M1650F	Neutral	0.012
BRCA1	P38398-1.2	M1650G	Neutral	0.134
BRCA1	P38398-1.2	M1650H	Neutral	0.022
BRCA1	P38398-1.2	M1650I	Neutral	0.007
BRCA1	P38398-1.2	M1650K	Neutral	0.017
BRCA1	P38398-1.2	M1650L	Neutral	0.005
BRCA1	P38398-1.2	M1650N	Neutral	0.035
BRCA1	P38398-1.2	M1650P	Neutral	0.041
BRCA1	P38398-1.2	M1650Q	Neutral	0.012
BRCA1	P38398-1.2	M1650R	Neutral	0.023
BRCA1	P38398-1.2	M1650S	Neutral	0.041
BRCA1	P38398-1.2	M1650T	Neutral	0.027
BRCA1	P38398-1.2	M1650V	Neutral	0.01
BRCA1	P38398-1.2	M1650W	Neutral	0.032
BRCA1	P38398-1.2	M1650Y	Neutral	0.02
BRCA1	P38398-1.2	S1651A	Neutral	0.411
BRCA1	P38398-1.2	S1651C	Pathogenic	0.625
BRCA1	P38398-1.2	S1651D	Pathogenic	0.565
BRCA1	P38398-1.2	S1651E	Pathogenic	0.661
BRCA1	P38398-1.2	S1651F	Pathogenic	0.875
BRCA1	P38398-1.2	S1651G	Pathogenic	0.606
BRCA1	P38398-1.2	S1651H	Pathogenic	0.775
BRCA1	P38398-1.2	S1651I	Pathogenic	0.846
BRCA1	P38398-1.2	S1651K	Pathogenic	0.775
BRCA1	P38398-1.2	S1651L	Pathogenic	0.846
BRCA1	P38398-1.2	S1651M	Pathogenic	0.794
BRCA1	P38398-1.2	S1651N	Pathogenic	0.503
BRCA1	P38398-1.2	S1651P	Pathogenic	0.647
BRCA1	P38398-1.2	S1651Q	Pathogenic	0.687
BRCA1	P38398-1.2	S1651R	Pathogenic	0.869
BRCA1	P38398-1.2	S1651T	Neutral	0.488
BRCA1	P38398-1.2	S1651V	Pathogenic	0.785
BRCA1	P38398-1.2	S1651W	Pathogenic	0.949
BRCA1	P38398-1.2	S1651Y	Pathogenic	0.891
BRCA1	P38398-1.2	M1652A	Pathogenic	0.526
BRCA1	P38398-1.2	M1652C	Neutral	0.424
BRCA1	P38398-1.2	M1652D	Pathogenic	0.569
BRCA1	P38398-1.2	M1652E	Neutral	0.382
BRCA1	P38398-1.2	M1652F	Neutral	0.219
BRCA1	P38398-1.2	M1652G	Pathogenic	0.777
BRCA1	P38398-1.2	M1652H	Neutral	0.339
BRCA1	P38398-1.2	M1652I	Neutral	0.132
BRCA1	P38398-1.2	M1652K	Neutral	0.28
BRCA1	P38398-1.2	M1652L	Neutral	0.096
BRCA1	P38398-1.2	M1652N	Neutral	0.452
BRCA1	P38398-1.2	M1652P	Neutral	0.491
BRCA1	P38398-1.2	M1652Q	Neutral	0.212
BRCA1	P38398-1.2	M1652R	Neutral	0.342
BRCA1	P38398-1.2	M1652S	Neutral	0.491
BRCA1	P38398-1.2	M1652T	Neutral	0.384
BRCA1	P38398-1.2	M1652V	Neutral	0.19
BRCA1	P38398-1.2	M1652W	Neutral	0.426
BRCA1	P38398-1.2	M1652Y	Neutral	0.316
BRCA1	P38398-1.2	V1653A	Pathogenic	0.768
BRCA1	P38398-1.2	V1653C	Pathogenic	0.76
BRCA1	P38398-1.2	V1653D	Pathogenic	0.85
BRCA1	P38398-1.2	V1653E	Pathogenic	0.76
BRCA1	P38398-1.2	V1653F	Pathogenic	0.8
BRCA1	P38398-1.2	V1653G	Pathogenic	0.937
BRCA1	P38398-1.2	V1653H	Pathogenic	0.849
BRCA1	P38398-1.2	V1653I	Neutral	0.423
BRCA1	P38398-1.2	V1653K	Pathogenic	0.848
BRCA1	P38398-1.2	V1653L	Pathogenic	0.603
BRCA1	P38398-1.2	V1653M	Pathogenic	0.605
BRCA1	P38398-1.2	V1653N	Pathogenic	0.836
BRCA1	P38398-1.2	V1653P	Pathogenic	0.805
BRCA1	P38398-1.2	V1653Q	Pathogenic	0.781
BRCA1	P38398-1.2	V1653R	Pathogenic	0.915
BRCA1	P38398-1.2	V1653S	Pathogenic	0.856
BRCA1	P38398-1.2	V1653T	Pathogenic	0.65
BRCA1	P38398-1.2	V1653W	Pathogenic	0.939
BRCA1	P38398-1.2	V1653Y	Pathogenic	0.822
BRCA1	P38398-1.2	V1654A	Neutral	0.034
BRCA1	P38398-1.2	V1654C	Neutral	0.032
BRCA1	P38398-1.2	V1654D	Neutral	0.056
BRCA1	P38398-1.2	V1654E	Neutral	0.032
BRCA1	P38398-1.2	V1654F	Neutral	0.04
BRCA1	P38398-1.2	V1654G	Neutral	0.136
BRCA1	P38398-1.2	V1654H	Neutral	0.056
BRCA1	P38398-1.2	V1654I	Neutral	0.008
BRCA1	P38398-1.2	V1654K	Neutral	0.056
BRCA1	P38398-1.2	V1654L	Neutral	0.016
BRCA1	P38398-1.2	V1654M	Neutral	0.016
BRCA1	P38398-1.2	V1654N	Neutral	0.051
BRCA1	P38398-1.2	V1654P	Neutral	0.042
BRCA1	P38398-1.2	V1654Q	Neutral	0.036
BRCA1	P38398-1.2	V1654R	Neutral	0.101
BRCA1	P38398-1.2	V1654S	Neutral	0.059
BRCA1	P38398-1.2	V1654T	Neutral	0.019
BRCA1	P38398-1.2	V1654W	Neutral	0.139
BRCA1	P38398-1.2	V1654Y	Neutral	0.046
BRCA1	P38398-1.2	S1655A	Neutral	0.388
BRCA1	P38398-1.2	S1655C	Pathogenic	0.602
BRCA1	P38398-1.2	S1655D	Pathogenic	0.541
BRCA1	P38398-1.2	S1655E	Pathogenic	0.638
BRCA1	P38398-1.2	S1655F	Pathogenic	0.864
BRCA1	P38398-1.2	S1655G	Pathogenic	0.583
BRCA1	P38398-1.2	S1655H	Pathogenic	0.758
BRCA1	P38398-1.2	S1655I	Pathogenic	0.833
BRCA1	P38398-1.2	S1655K	Pathogenic	0.757
BRCA1	P38398-1.2	S1655L	Pathogenic	0.833
BRCA1	P38398-1.2	S1655M	Pathogenic	0.778
BRCA1	P38398-1.2	S1655N	Neutral	0.479
BRCA1	P38398-1.2	S1655P	Pathogenic	0.624
BRCA1	P38398-1.2	S1655Q	Pathogenic	0.665
BRCA1	P38398-1.2	S1655R	Pathogenic	0.857
BRCA1	P38398-1.2	S1655T	Neutral	0.464
BRCA1	P38398-1.2	S1655V	Pathogenic	0.768
BRCA1	P38398-1.2	S1655W	Pathogenic	0.944
BRCA1	P38398-1.2	S1655Y	Pathogenic	0.881
BRCA1	P38398-1.2	G1656A	Pathogenic	0.707
BRCA1	P38398-1.2	G1656C	Pathogenic	0.915
BRCA1	P38398-1.2	G1656D	Pathogenic	0.854
BRCA1	P38398-1.2	G1656E	Pathogenic	0.927
BRCA1	P38398-1.2	G1656F	Pathogenic	0.969
BRCA1	P38398-1.2	G1656H	Pathogenic	0.94
BRCA1	P38398-1.2	G1656I	Pathogenic	0.973
BRCA1	P38398-1.2	G1656K	Pathogenic	0.957
BRCA1	P38398-1.2	G1656L	Pathogenic	0.973
BRCA1	P38398-1.2	G1656M	Pathogenic	0.962
BRCA1	P38398-1.2	G1656N	Pathogenic	0.821
BRCA1	P38398-1.2	G1656P	Pathogenic	0.892
BRCA1	P38398-1.2	G1656Q	Pathogenic	0.934
BRCA1	P38398-1.2	G1656R	Pathogenic	0.968
BRCA1	P38398-1.2	G1656S	Pathogenic	0.735
BRCA1	P38398-1.2	G1656T	Pathogenic	0.899
BRCA1	P38398-1.2	G1656V	Pathogenic	0.943
BRCA1	P38398-1.2	G1656W	Pathogenic	0.976
BRCA1	P38398-1.2	G1656Y	Pathogenic	0.974
BRCA1	P38398-1.2	L1657A	Pathogenic	0.851
BRCA1	P38398-1.2	L1657C	Pathogenic	0.792
BRCA1	P38398-1.2	L1657D	Pathogenic	0.907
BRCA1	P38398-1.2	L1657E	Pathogenic	0.821
BRCA1	P38398-1.2	L1657F	Pathogenic	0.595
BRCA1	P38398-1.2	L1657G	Pathogenic	0.963
BRCA1	P38398-1.2	L1657H	Pathogenic	0.792
BRCA1	P38398-1.2	L1657I	Neutral	0.357
BRCA1	P38398-1.2	L1657K	Pathogenic	0.743
BRCA1	P38398-1.2	L1657M	Neutral	0.355
BRCA1	P38398-1.2	L1657N	Pathogenic	0.86
BRCA1	P38398-1.2	L1657P	Pathogenic	0.878
BRCA1	P38398-1.2	L1657Q	Pathogenic	0.742
BRCA1	P38398-1.2	L1657R	Pathogenic	0.794
BRCA1	P38398-1.2	L1657S	Pathogenic	0.877
BRCA1	P38398-1.2	L1657T	Pathogenic	0.762
BRCA1	P38398-1.2	L1657V	Pathogenic	0.547
BRCA1	P38398-1.2	L1657W	Pathogenic	0.849
BRCA1	P38398-1.2	L1657Y	Pathogenic	0.705
BRCA1	P38398-1.2	T1658A	Neutral	0.419
BRCA1	P38398-1.2	T1658C	Neutral	0.402
BRCA1	P38398-1.2	T1658D	Neutral	0.374
BRCA1	P38398-1.2	T1658E	Neutral	0.45
BRCA1	P38398-1.2	T1658F	Pathogenic	0.674
BRCA1	P38398-1.2	T1658G	Pathogenic	0.694
BRCA1	P38398-1.2	T1658H	Pathogenic	0.593
BRCA1	P38398-1.2	T1658I	Pathogenic	0.53
BRCA1	P38398-1.2	T1658K	Pathogenic	0.591
BRCA1	P38398-1.2	T1658L	Pathogenic	0.53
BRCA1	P38398-1.2	T1658M	Pathogenic	0.533
BRCA1	P38398-1.2	T1658N	Neutral	0.299
BRCA1	P38398-1.2	T1658P	Neutral	0.382
BRCA1	P38398-1.2	T1658Q	Neutral	0.48
BRCA1	P38398-1.2	T1658R	Pathogenic	0.659
BRCA1	P38398-1.2	T1658S	Neutral	0.304
BRCA1	P38398-1.2	T1658V	Neutral	0.342
BRCA1	P38398-1.2	T1658W	Pathogenic	0.793
BRCA1	P38398-1.2	T1658Y	Pathogenic	0.706
BRCA1	P38398-1.2	P1659A	Neutral	0.021
BRCA1	P38398-1.2	P1659C	Neutral	0.028
BRCA1	P38398-1.2	P1659D	Neutral	0.013
BRCA1	P38398-1.2	P1659E	Neutral	0.019
BRCA1	P38398-1.2	P1659F	Neutral	0.093
BRCA1	P38398-1.2	P1659G	Neutral	0.044
BRCA1	P38398-1.2	P1659H	Neutral	0.033
BRCA1	P38398-1.2	P1659I	Neutral	0.053
BRCA1	P38398-1.2	P1659K	Neutral	0.033
BRCA1	P38398-1.2	P1659L	Neutral	0.053
BRCA1	P38398-1.2	P1659M	Neutral	0.038
BRCA1	P38398-1.2	P1659N	Neutral	0.02
BRCA1	P38398-1.2	P1659Q	Neutral	0.021
BRCA1	P38398-1.2	P1659R	Neutral	0.061
BRCA1	P38398-1.2	P1659S	Neutral	0.018
BRCA1	P38398-1.2	P1659T	Neutral	0.013
BRCA1	P38398-1.2	P1659V	Neutral	0.025
BRCA1	P38398-1.2	P1659W	Neutral	0.159
BRCA1	P38398-1.2	P1659Y	Neutral	0.076
BRCA1	P38398-1.2	E1660A	Neutral	0.103
BRCA1	P38398-1.2	E1660C	Neutral	0.181
BRCA1	P38398-1.2	E1660D	Neutral	0.022
BRCA1	P38398-1.2	E1660F	Neutral	0.139
BRCA1	P38398-1.2	E1660G	Neutral	0.202
BRCA1	P38398-1.2	E1660H	Neutral	0.037
BRCA1	P38398-1.2	E1660I	Neutral	0.112
BRCA1	P38398-1.2	E1660K	Neutral	0.038
BRCA1	P38398-1.2	E1660L	Neutral	0.113
BRCA1	P38398-1.2	E1660M	Neutral	0.082
BRCA1	P38398-1.2	E1660N	Neutral	0.041
BRCA1	P38398-1.2	E1660P	Neutral	0.064
BRCA1	P38398-1.2	E1660Q	Neutral	0.017
BRCA1	P38398-1.2	E1660R	Neutral	0.07
BRCA1	P38398-1.2	E1660S	Neutral	0.066
BRCA1	P38398-1.2	E1660T	Neutral	0.06
BRCA1	P38398-1.2	E1660V	Neutral	0.065
BRCA1	P38398-1.2	E1660W	Neutral	0.23
BRCA1	P38398-1.2	E1660Y	Neutral	0.115
BRCA1	P38398-1.2	E1661A	Pathogenic	0.54
BRCA1	P38398-1.2	E1661C	Pathogenic	0.694
BRCA1	P38398-1.2	E1661D	Neutral	0.19
BRCA1	P38398-1.2	E1661F	Pathogenic	0.624
BRCA1	P38398-1.2	E1661G	Pathogenic	0.722
BRCA1	P38398-1.2	E1661H	Neutral	0.282
BRCA1	P38398-1.2	E1661I	Pathogenic	0.565
BRCA1	P38398-1.2	E1661K	Neutral	0.287
BRCA1	P38398-1.2	E1661L	Pathogenic	0.565
BRCA1	P38398-1.2	E1661M	Neutral	0.477
BRCA1	P38398-1.2	E1661N	Neutral	0.304
BRCA1	P38398-1.2	E1661P	Neutral	0.411
BRCA1	P38398-1.2	E1661Q	Neutral	0.149
BRCA1	P38398-1.2	E1661R	Neutral	0.436
BRCA1	P38398-1.2	E1661S	Neutral	0.418
BRCA1	P38398-1.2	E1661T	Neutral	0.397
BRCA1	P38398-1.2	E1661V	Neutral	0.417
BRCA1	P38398-1.2	E1661W	Pathogenic	0.754
BRCA1	P38398-1.2	E1661Y	Pathogenic	0.572
BRCA1	P38398-1.2	F1662A	Neutral	0.019
BRCA1	P38398-1.2	F1662C	Neutral	0.013
BRCA1	P38398-1.2	F1662D	Neutral	0.016
BRCA1	P38398-1.2	F1662E	Neutral	0.011
BRCA1	P38398-1.2	F1662G	Neutral	0.041
BRCA1	P38398-1.2	F1662H	Neutral	0.004
BRCA1	P38398-1.2	F1662I	Neutral	0.003
BRCA1	P38398-1.2	F1662K	Neutral	0.006
BRCA1	P38398-1.2	F1662L	Neutral	0.003
BRCA1	P38398-1.2	F1662M	Neutral	0.003
BRCA1	P38398-1.2	F1662N	Neutral	0.014
BRCA1	P38398-1.2	F1662P	Neutral	0.024
BRCA1	P38398-1.2	F1662Q	Neutral	0.01
BRCA1	P38398-1.2	F1662R	Neutral	0.008
BRCA1	P38398-1.2	F1662S	Neutral	0.017
BRCA1	P38398-1.2	F1662T	Neutral	0.011
BRCA1	P38398-1.2	F1662V	Neutral	0.006
BRCA1	P38398-1.2	F1662W	Neutral	0.003
BRCA1	P38398-1.2	F1662Y	Neutral	0.001
BRCA1	P38398-1.2	M1663A	Neutral	0.331
BRCA1	P38398-1.2	M1663C	Neutral	0.247
BRCA1	P38398-1.2	M1663D	Neutral	0.371
BRCA1	P38398-1.2	M1663E	Neutral	0.216
BRCA1	P38398-1.2	M1663F	Neutral	0.111
BRCA1	P38398-1.2	M1663G	Pathogenic	0.609
BRCA1	P38398-1.2	M1663H	Neutral	0.186
BRCA1	P38398-1.2	M1663I	Neutral	0.064
BRCA1	P38398-1.2	M1663K	Neutral	0.148
BRCA1	P38398-1.2	M1663L	Neutral	0.045
BRCA1	P38398-1.2	M1663N	Neutral	0.269
BRCA1	P38398-1.2	M1663P	Neutral	0.301
BRCA1	P38398-1.2	M1663Q	Neutral	0.107
BRCA1	P38398-1.2	M1663R	Neutral	0.188
BRCA1	P38398-1.2	M1663S	Neutral	0.301
BRCA1	P38398-1.2	M1663T	Neutral	0.217
BRCA1	P38398-1.2	M1663V	Neutral	0.095
BRCA1	P38398-1.2	M1663W	Neutral	0.249
BRCA1	P38398-1.2	M1663Y	Neutral	0.171
BRCA1	P38398-1.2	L1664A	Neutral	0.178
BRCA1	P38398-1.2	L1664C	Neutral	0.126
BRCA1	P38398-1.2	L1664D	Neutral	0.271
BRCA1	P38398-1.2	L1664E	Neutral	0.148
BRCA1	P38398-1.2	L1664F	Neutral	0.053
BRCA1	P38398-1.2	L1664G	Neutral	0.495
BRCA1	P38398-1.2	L1664H	Neutral	0.126
BRCA1	P38398-1.2	L1664I	Neutral	0.021
BRCA1	P38398-1.2	L1664K	Neutral	0.099
BRCA1	P38398-1.2	L1664M	Neutral	0.02
BRCA1	P38398-1.2	L1664N	Neutral	0.188
BRCA1	P38398-1.2	L1664P	Neutral	0.214
BRCA1	P38398-1.2	L1664Q	Neutral	0.098
BRCA1	P38398-1.2	L1664R	Neutral	0.128
BRCA1	P38398-1.2	L1664S	Neutral	0.214
BRCA1	P38398-1.2	L1664T	Neutral	0.109
BRCA1	P38398-1.2	L1664V	Neutral	0.044
BRCA1	P38398-1.2	L1664W	Neutral	0.176
BRCA1	P38398-1.2	L1664Y	Neutral	0.083
BRCA1	P38398-1.2	V1665A	Neutral	0.416
BRCA1	P38398-1.2	V1665C	Neutral	0.405
BRCA1	P38398-1.2	V1665D	Pathogenic	0.549
BRCA1	P38398-1.2	V1665E	Neutral	0.405
BRCA1	P38398-1.2	V1665F	Neutral	0.463
BRCA1	P38398-1.2	V1665G	Pathogenic	0.763
BRCA1	P38398-1.2	V1665H	Pathogenic	0.548
BRCA1	P38398-1.2	V1665I	Neutral	0.136
BRCA1	P38398-1.2	V1665K	Pathogenic	0.546
BRCA1	P38398-1.2	V1665L	Neutral	0.246
BRCA1	P38398-1.2	V1665M	Neutral	0.248
BRCA1	P38398-1.2	V1665N	Pathogenic	0.523
BRCA1	P38398-1.2	V1665P	Neutral	0.471
BRCA1	P38398-1.2	V1665Q	Neutral	0.434
BRCA1	P38398-1.2	V1665R	Pathogenic	0.698
BRCA1	P38398-1.2	V1665S	Pathogenic	0.562
BRCA1	P38398-1.2	V1665T	Neutral	0.285
BRCA1	P38398-1.2	V1665W	Pathogenic	0.767
BRCA1	P38398-1.2	V1665Y	Neutral	0.498
BRCA1	P38398-1.2	Y1666A	Neutral	0.206
BRCA1	P38398-1.2	Y1666C	Neutral	0.147
BRCA1	P38398-1.2	Y1666D	Neutral	0.176
BRCA1	P38398-1.2	Y1666E	Neutral	0.091
BRCA1	P38398-1.2	Y1666F	Neutral	0.009
BRCA1	P38398-1.2	Y1666G	Neutral	0.361
BRCA1	P38398-1.2	Y1666H	Neutral	0.019
BRCA1	P38398-1.2	Y1666I	Neutral	0.048
BRCA1	P38398-1.2	Y1666K	Neutral	0.053
BRCA1	P38398-1.2	Y1666L	Neutral	0.048
BRCA1	P38398-1.2	Y1666M	Neutral	0.049
BRCA1	P38398-1.2	Y1666N	Neutral	0.118
BRCA1	P38398-1.2	Y1666P	Neutral	0.184
BRCA1	P38398-1.2	Y1666Q	Neutral	0.059
BRCA1	P38398-1.2	Y1666R	Neutral	0.054
BRCA1	P38398-1.2	Y1666S	Neutral	0.184
BRCA1	P38398-1.2	Y1666T	Neutral	0.127
BRCA1	P38398-1.2	Y1666V	Neutral	0.072
BRCA1	P38398-1.2	Y1666W	Neutral	0.018
BRCA1	P38398-1.2	K1667A	Pathogenic	0.79
BRCA1	P38398-1.2	K1667C	Pathogenic	0.835
BRCA1	P38398-1.2	K1667D	Pathogenic	0.693
BRCA1	P38398-1.2	K1667E	Neutral	0.422
BRCA1	P38398-1.2	K1667F	Pathogenic	0.626
BRCA1	P38398-1.2	K1667G	Pathogenic	0.893
BRCA1	P38398-1.2	K1667H	Pathogenic	0.549
BRCA1	P38398-1.2	K1667I	Pathogenic	0.681
BRCA1	P38398-1.2	K1667L	Pathogenic	0.598
BRCA1	P38398-1.2	K1667M	Pathogenic	0.511
BRCA1	P38398-1.2	K1667N	Pathogenic	0.583
BRCA1	P38398-1.2	K1667P	Pathogenic	0.692
BRCA1	P38398-1.2	K1667Q	Neutral	0.393
BRCA1	P38398-1.2	K1667R	Neutral	0.276
BRCA1	P38398-1.2	K1667S	Pathogenic	0.698
BRCA1	P38398-1.2	K1667T	Pathogenic	0.679
BRCA1	P38398-1.2	K1667V	Pathogenic	0.696
BRCA1	P38398-1.2	K1667W	Pathogenic	0.756
BRCA1	P38398-1.2	K1667Y	Pathogenic	0.575
BRCA1	P38398-1.2	F1668A	Pathogenic	0.94
BRCA1	P38398-1.2	F1668C	Pathogenic	0.912
BRCA1	P38398-1.2	F1668D	Pathogenic	0.928
BRCA1	P38398-1.2	F1668E	Pathogenic	0.897
BRCA1	P38398-1.2	F1668G	Pathogenic	0.972
BRCA1	P38398-1.2	F1668H	Pathogenic	0.777
BRCA1	P38398-1.2	F1668I	Pathogenic	0.686
BRCA1	P38398-1.2	F1668K	Pathogenic	0.829
BRCA1	P38398-1.2	F1668L	Pathogenic	0.686
BRCA1	P38398-1.2	F1668M	Pathogenic	0.684
BRCA1	P38398-1.2	F1668N	Pathogenic	0.921
BRCA1	P38398-1.2	F1668P	Pathogenic	0.951
BRCA1	P38398-1.2	F1668Q	Pathogenic	0.887
BRCA1	P38398-1.2	F1668R	Pathogenic	0.866
BRCA1	P38398-1.2	F1668S	Pathogenic	0.931
BRCA1	P38398-1.2	F1668T	Pathogenic	0.898
BRCA1	P38398-1.2	F1668V	Pathogenic	0.826
BRCA1	P38398-1.2	F1668W	Pathogenic	0.687
BRCA1	P38398-1.2	F1668Y	Neutral	0.393
BRCA1	P38398-1.2	A1669C	Pathogenic	0.605
BRCA1	P38398-1.2	A1669D	Pathogenic	0.779
BRCA1	P38398-1.2	A1669E	Pathogenic	0.785
BRCA1	P38398-1.2	A1669F	Pathogenic	0.903
BRCA1	P38398-1.2	A1669G	Pathogenic	0.607
BRCA1	P38398-1.2	A1669H	Pathogenic	0.867
BRCA1	P38398-1.2	A1669I	Pathogenic	0.835
BRCA1	P38398-1.2	A1669K	Pathogenic	0.866
BRCA1	P38398-1.2	A1669L	Pathogenic	0.835
BRCA1	P38398-1.2	A1669M	Pathogenic	0.836
BRCA1	P38398-1.2	A1669N	Pathogenic	0.798
BRCA1	P38398-1.2	A1669P	Pathogenic	0.708
BRCA1	P38398-1.2	A1669Q	Pathogenic	0.805
BRCA1	P38398-1.2	A1669R	Pathogenic	0.896
BRCA1	P38398-1.2	A1669S	Neutral	0.445
BRCA1	P38398-1.2	A1669T	Pathogenic	0.644
BRCA1	P38398-1.2	A1669V	Pathogenic	0.699
BRCA1	P38398-1.2	A1669W	Pathogenic	0.961
BRCA1	P38398-1.2	A1669Y	Pathogenic	0.915
BRCA1	P38398-1.2	R1670A	Neutral	0.417
BRCA1	P38398-1.2	R1670C	Neutral	0.489
BRCA1	P38398-1.2	R1670D	Neutral	0.381
BRCA1	P38398-1.2	R1670E	Neutral	0.166
BRCA1	P38398-1.2	R1670F	Neutral	0.241
BRCA1	P38398-1.2	R1670G	Pathogenic	0.612
BRCA1	P38398-1.2	R1670H	Neutral	0.138
BRCA1	P38398-1.2	R1670I	Neutral	0.288
BRCA1	P38398-1.2	R1670K	Neutral	0.051
BRCA1	P38398-1.2	R1670L	Neutral	0.22
BRCA1	P38398-1.2	R1670M	Neutral	0.165
BRCA1	P38398-1.2	R1670N	Neutral	0.21
BRCA1	P38398-1.2	R1670P	Neutral	0.38
BRCA1	P38398-1.2	R1670Q	Neutral	0.109
BRCA1	P38398-1.2	R1670S	Neutral	0.386
BRCA1	P38398-1.2	R1670T	Neutral	0.286
BRCA1	P38398-1.2	R1670V	Neutral	0.385
BRCA1	P38398-1.2	R1670W	Neutral	0.248
BRCA1	P38398-1.2	R1670Y	Neutral	0.164
BRCA1	P38398-1.2	K1671A	Pathogenic	0.634
BRCA1	P38398-1.2	K1671C	Pathogenic	0.699
BRCA1	P38398-1.2	K1671D	Pathogenic	0.509
BRCA1	P38398-1.2	K1671E	Neutral	0.251
BRCA1	P38398-1.2	K1671F	Neutral	0.435
BRCA1	P38398-1.2	K1671G	Pathogenic	0.793
BRCA1	P38398-1.2	K1671H	Neutral	0.359
BRCA1	P38398-1.2	K1671I	Neutral	0.495
BRCA1	P38398-1.2	K1671L	Neutral	0.406
BRCA1	P38398-1.2	K1671M	Neutral	0.324
BRCA1	P38398-1.2	K1671N	Neutral	0.391
BRCA1	P38398-1.2	K1671P	Pathogenic	0.507
BRCA1	P38398-1.2	K1671Q	Neutral	0.229
BRCA1	P38398-1.2	K1671R	Neutral	0.149
BRCA1	P38398-1.2	K1671S	Pathogenic	0.514
BRCA1	P38398-1.2	K1671T	Neutral	0.493
BRCA1	P38398-1.2	K1671V	Pathogenic	0.513
BRCA1	P38398-1.2	K1671W	Pathogenic	0.587
BRCA1	P38398-1.2	K1671Y	Neutral	0.383
BRCA1	P38398-1.2	H1672A	Neutral	0.144
BRCA1	P38398-1.2	H1672C	Neutral	0.136
BRCA1	P38398-1.2	H1672D	Neutral	0.064
BRCA1	P38398-1.2	H1672E	Neutral	0.031
BRCA1	P38398-1.2	H1672F	Neutral	0.051
BRCA1	P38398-1.2	H1672G	Neutral	0.205
BRCA1	P38398-1.2	H1672I	Neutral	0.08
BRCA1	P38398-1.2	H1672K	Neutral	0.051
BRCA1	P38398-1.2	H1672L	Neutral	0.08
BRCA1	P38398-1.2	H1672M	Neutral	0.057
BRCA1	P38398-1.2	H1672N	Neutral	0.029
BRCA1	P38398-1.2	H1672P	Neutral	0.091
BRCA1	P38398-1.2	H1672Q	Neutral	0.028
BRCA1	P38398-1.2	H1672R	Neutral	0.048
BRCA1	P38398-1.2	H1672S	Neutral	0.093
BRCA1	P38398-1.2	H1672T	Neutral	0.087
BRCA1	P38398-1.2	H1672V	Neutral	0.093
BRCA1	P38398-1.2	H1672W	Neutral	0.124
BRCA1	P38398-1.2	H1672Y	Neutral	0.02
BRCA1	P38398-1.2	H1673A	Neutral	0.45
BRCA1	P38398-1.2	H1673C	Neutral	0.432
BRCA1	P38398-1.2	H1673D	Neutral	0.247
BRCA1	P38398-1.2	H1673E	Neutral	0.133
BRCA1	P38398-1.2	H1673F	Neutral	0.206
BRCA1	P38398-1.2	H1673G	Pathogenic	0.555
BRCA1	P38398-1.2	H1673I	Neutral	0.296
BRCA1	P38398-1.2	H1673K	Neutral	0.208
BRCA1	P38398-1.2	H1673L	Neutral	0.297
BRCA1	P38398-1.2	H1673M	Neutral	0.228
BRCA1	P38398-1.2	H1673N	Neutral	0.125
BRCA1	P38398-1.2	H1673P	Neutral	0.327
BRCA1	P38398-1.2	H1673Q	Neutral	0.122
BRCA1	P38398-1.2	H1673R	Neutral	0.196
BRCA1	P38398-1.2	H1673S	Neutral	0.332
BRCA1	P38398-1.2	H1673T	Neutral	0.315
BRCA1	P38398-1.2	H1673V	Neutral	0.332
BRCA1	P38398-1.2	H1673W	Neutral	0.408
BRCA1	P38398-1.2	H1673Y	Neutral	0.092
BRCA1	P38398-1.2	I1674A	Neutral	0.068
BRCA1	P38398-1.2	I1674C	Neutral	0.046
BRCA1	P38398-1.2	I1674D	Neutral	0.08
BRCA1	P38398-1.2	I1674E	Neutral	0.055
BRCA1	P38398-1.2	I1674F	Neutral	0.019
BRCA1	P38398-1.2	I1674G	Neutral	0.249
BRCA1	P38398-1.2	I1674H	Neutral	0.046
BRCA1	P38398-1.2	I1674K	Neutral	0.051
BRCA1	P38398-1.2	I1674L	Neutral	0.007
BRCA1	P38398-1.2	I1674M	Neutral	0.01
BRCA1	P38398-1.2	I1674N	Neutral	0.073
BRCA1	P38398-1.2	I1674P	Neutral	0.084
BRCA1	P38398-1.2	I1674Q	Neutral	0.05
BRCA1	P38398-1.2	I1674R	Neutral	0.066
BRCA1	P38398-1.2	I1674S	Neutral	0.084
BRCA1	P38398-1.2	I1674T	Neutral	0.039
BRCA1	P38398-1.2	I1674V	Neutral	0.007
BRCA1	P38398-1.2	I1674W	Neutral	0.094
BRCA1	P38398-1.2	I1674Y	Neutral	0.03
BRCA1	P38398-1.2	T1675A	Neutral	0.009
BRCA1	P38398-1.2	T1675C	Neutral	0.008
BRCA1	P38398-1.2	T1675D	Neutral	0.007
BRCA1	P38398-1.2	T1675E	Neutral	0.01
BRCA1	P38398-1.2	T1675F	Neutral	0.025
BRCA1	P38398-1.2	T1675G	Neutral	0.027
BRCA1	P38398-1.2	T1675H	Neutral	0.018
BRCA1	P38398-1.2	T1675I	Neutral	0.014
BRCA1	P38398-1.2	T1675K	Neutral	0.017
BRCA1	P38398-1.2	T1675L	Neutral	0.014
BRCA1	P38398-1.2	T1675M	Neutral	0.014
BRCA1	P38398-1.2	T1675N	Neutral	0.005
BRCA1	P38398-1.2	T1675P	Neutral	0.008
BRCA1	P38398-1.2	T1675Q	Neutral	0.011
BRCA1	P38398-1.2	T1675R	Neutral	0.023
BRCA1	P38398-1.2	T1675S	Neutral	0.005
BRCA1	P38398-1.2	T1675V	Neutral	0.006
BRCA1	P38398-1.2	T1675W	Neutral	0.045
BRCA1	P38398-1.2	T1675Y	Neutral	0.029
BRCA1	P38398-1.2	L1676A	Neutral	0.382
BRCA1	P38398-1.2	L1676C	Neutral	0.291
BRCA1	P38398-1.2	L1676D	Pathogenic	0.514
BRCA1	P38398-1.2	L1676E	Neutral	0.331
BRCA1	P38398-1.2	L1676F	Neutral	0.137
BRCA1	P38398-1.2	L1676G	Pathogenic	0.736
BRCA1	P38398-1.2	L1676H	Neutral	0.291
BRCA1	P38398-1.2	L1676I	Neutral	0.057
BRCA1	P38398-1.2	L1676K	Neutral	0.238
BRCA1	P38398-1.2	L1676M	Neutral	0.056
BRCA1	P38398-1.2	L1676N	Neutral	0.398
BRCA1	P38398-1.2	L1676P	Neutral	0.436
BRCA1	P38398-1.2	L1676Q	Neutral	0.237
BRCA1	P38398-1.2	L1676R	Neutral	0.294
BRCA1	P38398-1.2	L1676S	Neutral	0.436
BRCA1	P38398-1.2	L1676T	Neutral	0.257
BRCA1	P38398-1.2	L1676V	Neutral	0.115
BRCA1	P38398-1.2	L1676W	Neutral	0.377
BRCA1	P38398-1.2	L1676Y	Neutral	0.205
BRCA1	P38398-1.2	T1677A	Neutral	0.161
BRCA1	P38398-1.2	T1677C	Neutral	0.151
BRCA1	P38398-1.2	T1677D	Neutral	0.137
BRCA1	P38398-1.2	T1677E	Neutral	0.179
BRCA1	P38398-1.2	T1677F	Neutral	0.355
BRCA1	P38398-1.2	T1677G	Neutral	0.376
BRCA1	P38398-1.2	T1677H	Neutral	0.279
BRCA1	P38398-1.2	T1677I	Neutral	0.23
BRCA1	P38398-1.2	T1677K	Neutral	0.278
BRCA1	P38398-1.2	T1677L	Neutral	0.231
BRCA1	P38398-1.2	T1677M	Neutral	0.232
BRCA1	P38398-1.2	T1677N	Neutral	0.102
BRCA1	P38398-1.2	T1677P	Neutral	0.141
BRCA1	P38398-1.2	T1677Q	Neutral	0.197
BRCA1	P38398-1.2	T1677R	Neutral	0.339
BRCA1	P38398-1.2	T1677S	Neutral	0.104
BRCA1	P38398-1.2	T1677V	Neutral	0.121
BRCA1	P38398-1.2	T1677W	Pathogenic	0.504
BRCA1	P38398-1.2	T1677Y	Neutral	0.39
BRCA1	P38398-1.2	N1678A	Neutral	0.021
BRCA1	P38398-1.2	N1678C	Neutral	0.02
BRCA1	P38398-1.2	N1678D	Neutral	0.004
BRCA1	P38398-1.2	N1678E	Neutral	0.007
BRCA1	P38398-1.2	N1678F	Neutral	0.037
BRCA1	P38398-1.2	N1678G	Neutral	0.016
BRCA1	P38398-1.2	N1678H	Neutral	0.006
BRCA1	P38398-1.2	N1678I	Neutral	0.029
BRCA1	P38398-1.2	N1678K	Neutral	0.013
BRCA1	P38398-1.2	N1678L	Neutral	0.029
BRCA1	P38398-1.2	N1678M	Neutral	0.021
BRCA1	P38398-1.2	N1678P	Neutral	0.013
BRCA1	P38398-1.2	N1678Q	Neutral	0.008
BRCA1	P38398-1.2	N1678R	Neutral	0.017
BRCA1	P38398-1.2	N1678S	Neutral	0.006
BRCA1	P38398-1.2	N1678T	Neutral	0.006
BRCA1	P38398-1.2	N1678V	Neutral	0.019
BRCA1	P38398-1.2	N1678W	Neutral	0.092
BRCA1	P38398-1.2	N1678Y	Neutral	0.03
BRCA1	P38398-1.2	L1679A	Neutral	0.052
BRCA1	P38398-1.2	L1679C	Neutral	0.035
BRCA1	P38398-1.2	L1679D	Neutral	0.086
BRCA1	P38398-1.2	L1679E	Neutral	0.042
BRCA1	P38398-1.2	L1679F	Neutral	0.014
BRCA1	P38398-1.2	L1679G	Neutral	0.2
BRCA1	P38398-1.2	L1679H	Neutral	0.035
BRCA1	P38398-1.2	L1679I	Neutral	0.005
BRCA1	P38398-1.2	L1679K	Neutral	0.027
BRCA1	P38398-1.2	L1679M	Neutral	0.005
BRCA1	P38398-1.2	L1679N	Neutral	0.056
BRCA1	P38398-1.2	L1679P	Neutral	0.065
BRCA1	P38398-1.2	L1679Q	Neutral	0.027
BRCA1	P38398-1.2	L1679R	Neutral	0.036
BRCA1	P38398-1.2	L1679S	Neutral	0.065
BRCA1	P38398-1.2	L1679T	Neutral	0.03
BRCA1	P38398-1.2	L1679V	Neutral	0.012
BRCA1	P38398-1.2	L1679W	Neutral	0.051
BRCA1	P38398-1.2	L1679Y	Neutral	0.022
BRCA1	P38398-1.2	I1680A	Neutral	0.181
BRCA1	P38398-1.2	I1680C	Neutral	0.128
BRCA1	P38398-1.2	I1680D	Neutral	0.208
BRCA1	P38398-1.2	I1680E	Neutral	0.15
BRCA1	P38398-1.2	I1680F	Neutral	0.054
BRCA1	P38398-1.2	I1680G	Neutral	0.5
BRCA1	P38398-1.2	I1680H	Neutral	0.128
BRCA1	P38398-1.2	I1680K	Neutral	0.139
BRCA1	P38398-1.2	I1680L	Neutral	0.021
BRCA1	P38398-1.2	I1680M	Neutral	0.03
BRCA1	P38398-1.2	I1680N	Neutral	0.191
BRCA1	P38398-1.2	I1680P	Neutral	0.217
BRCA1	P38398-1.2	I1680Q	Neutral	0.138
BRCA1	P38398-1.2	I1680R	Neutral	0.177
BRCA1	P38398-1.2	I1680S	Neutral	0.217
BRCA1	P38398-1.2	I1680T	Neutral	0.11
BRCA1	P38398-1.2	I1680V	Neutral	0.022
BRCA1	P38398-1.2	I1680W	Neutral	0.239
BRCA1	P38398-1.2	I1680Y	Neutral	0.084
BRCA1	P38398-1.2	T1681A	Neutral	0.299
BRCA1	P38398-1.2	T1681C	Neutral	0.284
BRCA1	P38398-1.2	T1681D	Neutral	0.261
BRCA1	P38398-1.2	T1681E	Neutral	0.326
BRCA1	P38398-1.2	T1681F	Pathogenic	0.55
BRCA1	P38398-1.2	T1681G	Pathogenic	0.573
BRCA1	P38398-1.2	T1681H	Neutral	0.463
BRCA1	P38398-1.2	T1681I	Neutral	0.4
BRCA1	P38398-1.2	T1681K	Neutral	0.461
BRCA1	P38398-1.2	T1681L	Neutral	0.4
BRCA1	P38398-1.2	T1681M	Neutral	0.402
BRCA1	P38398-1.2	T1681N	Neutral	0.201
BRCA1	P38398-1.2	T1681P	Neutral	0.267
BRCA1	P38398-1.2	T1681Q	Neutral	0.352
BRCA1	P38398-1.2	T1681R	Pathogenic	0.533
BRCA1	P38398-1.2	T1681S	Neutral	0.205
BRCA1	P38398-1.2	T1681V	Neutral	0.235
BRCA1	P38398-1.2	T1681W	Pathogenic	0.693
BRCA1	P38398-1.2	T1681Y	Pathogenic	0.587
BRCA1	P38398-1.2	E1682A	Neutral	0.321
BRCA1	P38398-1.2	E1682C	Neutral	0.477
BRCA1	P38398-1.2	E1682D	Neutral	0.086
BRCA1	P38398-1.2	E1682F	Neutral	0.4
BRCA1	P38398-1.2	E1682G	Pathogenic	0.511
BRCA1	P38398-1.2	E1682H	Neutral	0.137
BRCA1	P38398-1.2	E1682I	Neutral	0.343
BRCA1	P38398-1.2	E1682K	Neutral	0.139
BRCA1	P38398-1.2	E1682L	Neutral	0.344
BRCA1	P38398-1.2	E1682M	Neutral	0.269
BRCA1	P38398-1.2	E1682N	Neutral	0.149
BRCA1	P38398-1.2	E1682P	Neutral	0.22
BRCA1	P38398-1.2	E1682Q	Neutral	0.066
BRCA1	P38398-1.2	E1682R	Neutral	0.237
BRCA1	P38398-1.2	E1682S	Neutral	0.225
BRCA1	P38398-1.2	E1682T	Neutral	0.21
BRCA1	P38398-1.2	E1682V	Neutral	0.223
BRCA1	P38398-1.2	E1682W	Pathogenic	0.552
BRCA1	P38398-1.2	E1682Y	Neutral	0.35
BRCA1	P38398-1.2	E1683A	Neutral	0.424
BRCA1	P38398-1.2	E1683C	Pathogenic	0.587
BRCA1	P38398-1.2	E1683D	Neutral	0.128
BRCA1	P38398-1.2	E1683F	Pathogenic	0.509
BRCA1	P38398-1.2	E1683G	Pathogenic	0.619
BRCA1	P38398-1.2	E1683H	Neutral	0.198
BRCA1	P38398-1.2	E1683I	Neutral	0.448
BRCA1	P38398-1.2	E1683K	Neutral	0.201
BRCA1	P38398-1.2	E1683L	Neutral	0.449
BRCA1	P38398-1.2	E1683M	Neutral	0.363
BRCA1	P38398-1.2	E1683N	Neutral	0.215
BRCA1	P38398-1.2	E1683P	Neutral	0.305
BRCA1	P38398-1.2	E1683Q	Neutral	0.099
BRCA1	P38398-1.2	E1683R	Neutral	0.326
BRCA1	P38398-1.2	E1683S	Neutral	0.311
BRCA1	P38398-1.2	E1683T	Neutral	0.292
BRCA1	P38398-1.2	E1683V	Neutral	0.309
BRCA1	P38398-1.2	E1683W	Pathogenic	0.657
BRCA1	P38398-1.2	E1683Y	Neutral	0.456
BRCA1	P38398-1.2	T1684A	Pathogenic	0.621
BRCA1	P38398-1.2	T1684C	Pathogenic	0.605
BRCA1	P38398-1.2	T1684D	Pathogenic	0.576
BRCA1	P38398-1.2	T1684E	Pathogenic	0.651
BRCA1	P38398-1.2	T1684F	Pathogenic	0.825
BRCA1	P38398-1.2	T1684G	Pathogenic	0.838
BRCA1	P38398-1.2	T1684H	Pathogenic	0.769
BRCA1	P38398-1.2	T1684I	Pathogenic	0.72
BRCA1	P38398-1.2	T1684K	Pathogenic	0.767
BRCA1	P38398-1.2	T1684L	Pathogenic	0.72
BRCA1	P38398-1.2	T1684M	Pathogenic	0.722
BRCA1	P38398-1.2	T1684N	Neutral	0.492
BRCA1	P38398-1.2	T1684P	Pathogenic	0.584
BRCA1	P38398-1.2	T1684Q	Pathogenic	0.677
BRCA1	P38398-1.2	T1684R	Pathogenic	0.815
BRCA1	P38398-1.2	T1684S	Neutral	0.498
BRCA1	P38398-1.2	T1684V	Pathogenic	0.542
BRCA1	P38398-1.2	T1684W	Pathogenic	0.897
BRCA1	P38398-1.2	T1684Y	Pathogenic	0.846
BRCA1	P38398-1.2	T1685A	Pathogenic	0.589
BRCA1	P38398-1.2	T1685C	Pathogenic	0.572
BRCA1	P38398-1.2	T1685D	Pathogenic	0.543
BRCA1	P38398-1.2	T1685E	Pathogenic	0.619
BRCA1	P38398-1.2	T1685F	Pathogenic	0.805
BRCA1	P38398-1.2	T1685G	Pathogenic	0.819
BRCA1	P38398-1.2	T1685H	Pathogenic	0.744
BRCA1	P38398-1.2	T1685I	Pathogenic	0.692
BRCA1	P38398-1.2	T1685K	Pathogenic	0.742
BRCA1	P38398-1.2	T1685L	Pathogenic	0.692
BRCA1	P38398-1.2	T1685M	Pathogenic	0.694
BRCA1	P38398-1.2	T1685N	Neutral	0.459
BRCA1	P38398-1.2	T1685P	Pathogenic	0.552
BRCA1	P38398-1.2	T1685Q	Pathogenic	0.647
BRCA1	P38398-1.2	T1685R	Pathogenic	0.794
BRCA1	P38398-1.2	T1685S	Neutral	0.465
BRCA1	P38398-1.2	T1685V	Pathogenic	0.508
BRCA1	P38398-1.2	T1685W	Pathogenic	0.884
BRCA1	P38398-1.2	T1685Y	Pathogenic	0.827
BRCA1	P38398-1.2	H1686A	Pathogenic	0.911
BRCA1	P38398-1.2	H1686C	Pathogenic	0.905
BRCA1	P38398-1.2	H1686D	Pathogenic	0.805
BRCA1	P38398-1.2	H1686E	Pathogenic	0.658
BRCA1	P38398-1.2	H1686F	Pathogenic	0.765
BRCA1	P38398-1.2	H1686G	Pathogenic	0.94
BRCA1	P38398-1.2	H1686I	Pathogenic	0.841
BRCA1	P38398-1.2	H1686K	Pathogenic	0.767
BRCA1	P38398-1.2	H1686L	Pathogenic	0.841
BRCA1	P38398-1.2	H1686M	Pathogenic	0.787
BRCA1	P38398-1.2	H1686N	Pathogenic	0.641
BRCA1	P38398-1.2	H1686P	Pathogenic	0.859
BRCA1	P38398-1.2	H1686Q	Pathogenic	0.634
BRCA1	P38398-1.2	H1686R	Pathogenic	0.753
BRCA1	P38398-1.2	H1686S	Pathogenic	0.862
BRCA1	P38398-1.2	H1686T	Pathogenic	0.852
BRCA1	P38398-1.2	H1686V	Pathogenic	0.862
BRCA1	P38398-1.2	H1686W	Pathogenic	0.896
BRCA1	P38398-1.2	H1686Y	Pathogenic	0.559
BRCA1	P38398-1.2	V1687A	Pathogenic	0.69
BRCA1	P38398-1.2	V1687C	Pathogenic	0.68
BRCA1	P38398-1.2	V1687D	Pathogenic	0.792
BRCA1	P38398-1.2	V1687E	Pathogenic	0.68
BRCA1	P38398-1.2	V1687F	Pathogenic	0.73
BRCA1	P38398-1.2	V1687G	Pathogenic	0.91
BRCA1	P38398-1.2	V1687H	Pathogenic	0.791
BRCA1	P38398-1.2	V1687I	Neutral	0.33
BRCA1	P38398-1.2	V1687K	Pathogenic	0.79
BRCA1	P38398-1.2	V1687L	Pathogenic	0.506
BRCA1	P38398-1.2	V1687M	Pathogenic	0.508
BRCA1	P38398-1.2	V1687N	Pathogenic	0.774
BRCA1	P38398-1.2	V1687P	Pathogenic	0.736
BRCA1	P38398-1.2	V1687Q	Pathogenic	0.706
BRCA1	P38398-1.2	V1687R	Pathogenic	0.878
BRCA1	P38398-1.2	V1687S	Pathogenic	0.8
BRCA1	P38398-1.2	V1687T	Pathogenic	0.555
BRCA1	P38398-1.2	V1687W	Pathogenic	0.912
BRCA1	P38398-1.2	V1687Y	Pathogenic	0.756
BRCA1	P38398-1.2	V1688A	Neutral	0.094
BRCA1	P38398-1.2	V1688C	Neutral	0.09
BRCA1	P38398-1.2	V1688D	Neutral	0.151
BRCA1	P38398-1.2	V1688E	Neutral	0.09
BRCA1	P38398-1.2	V1688F	Neutral	0.112
BRCA1	P38398-1.2	V1688G	Neutral	0.319
BRCA1	P38398-1.2	V1688H	Neutral	0.15
BRCA1	P38398-1.2	V1688I	Neutral	0.022
BRCA1	P38398-1.2	V1688K	Neutral	0.149
BRCA1	P38398-1.2	V1688L	Neutral	0.045
BRCA1	P38398-1.2	V1688M	Neutral	0.046
BRCA1	P38398-1.2	V1688N	Neutral	0.137
BRCA1	P38398-1.2	V1688P	Neutral	0.115
BRCA1	P38398-1.2	V1688Q	Neutral	0.1
BRCA1	P38398-1.2	V1688R	Neutral	0.252
BRCA1	P38398-1.2	V1688S	Neutral	0.157
BRCA1	P38398-1.2	V1688T	Neutral	0.055
BRCA1	P38398-1.2	V1688W	Neutral	0.324
BRCA1	P38398-1.2	V1688Y	Neutral	0.126
BRCA1	P38398-1.2	M1689A	Pathogenic	0.779
BRCA1	P38398-1.2	M1689C	Pathogenic	0.701
BRCA1	P38398-1.2	M1689D	Pathogenic	0.807
BRCA1	P38398-1.2	M1689E	Pathogenic	0.662
BRCA1	P38398-1.2	M1689F	Neutral	0.47
BRCA1	P38398-1.2	M1689G	Pathogenic	0.917
BRCA1	P38398-1.2	M1689H	Pathogenic	0.619
BRCA1	P38398-1.2	M1689I	Neutral	0.326
BRCA1	P38398-1.2	M1689K	Pathogenic	0.553
BRCA1	P38398-1.2	M1689L	Neutral	0.252
BRCA1	P38398-1.2	M1689N	Pathogenic	0.723
BRCA1	P38398-1.2	M1689P	Pathogenic	0.754
BRCA1	P38398-1.2	M1689Q	Neutral	0.46
BRCA1	P38398-1.2	M1689R	Pathogenic	0.623
BRCA1	P38398-1.2	M1689S	Pathogenic	0.754
BRCA1	P38398-1.2	M1689T	Pathogenic	0.664
BRCA1	P38398-1.2	M1689V	Neutral	0.427
BRCA1	P38398-1.2	M1689W	Pathogenic	0.702
BRCA1	P38398-1.2	M1689Y	Pathogenic	0.595
BRCA1	P38398-1.2	K1690A	Pathogenic	0.827
BRCA1	P38398-1.2	K1690C	Pathogenic	0.865
BRCA1	P38398-1.2	K1690D	Pathogenic	0.742
BRCA1	P38398-1.2	K1690E	Neutral	0.481
BRCA1	P38398-1.2	K1690F	Pathogenic	0.68
BRCA1	P38398-1.2	K1690G	Pathogenic	0.914
BRCA1	P38398-1.2	K1690H	Pathogenic	0.608
BRCA1	P38398-1.2	K1690I	Pathogenic	0.731
BRCA1	P38398-1.2	K1690L	Pathogenic	0.654
BRCA1	P38398-1.2	K1690M	Pathogenic	0.57
BRCA1	P38398-1.2	K1690N	Pathogenic	0.64
BRCA1	P38398-1.2	K1690P	Pathogenic	0.74
BRCA1	P38398-1.2	K1690Q	Neutral	0.451
BRCA1	P38398-1.2	K1690R	Neutral	0.327
BRCA1	P38398-1.2	K1690S	Pathogenic	0.746
BRCA1	P38398-1.2	K1690T	Pathogenic	0.729
BRCA1	P38398-1.2	K1690V	Pathogenic	0.744
BRCA1	P38398-1.2	K1690W	Pathogenic	0.797
BRCA1	P38398-1.2	K1690Y	Pathogenic	0.632
BRCA1	P38398-1.2	T1691A	Pathogenic	0.571
BRCA1	P38398-1.2	T1691C	Pathogenic	0.553
BRCA1	P38398-1.2	T1691D	Pathogenic	0.524
BRCA1	P38398-1.2	T1691E	Pathogenic	0.601
BRCA1	P38398-1.2	T1691F	Pathogenic	0.793
BRCA1	P38398-1.2	T1691G	Pathogenic	0.807
BRCA1	P38398-1.2	T1691H	Pathogenic	0.729
BRCA1	P38398-1.2	T1691I	Pathogenic	0.675
BRCA1	P38398-1.2	T1691K	Pathogenic	0.727
BRCA1	P38398-1.2	T1691L	Pathogenic	0.676
BRCA1	P38398-1.2	T1691M	Pathogenic	0.678
BRCA1	P38398-1.2	T1691N	Neutral	0.44
BRCA1	P38398-1.2	T1691P	Pathogenic	0.533
BRCA1	P38398-1.2	T1691Q	Pathogenic	0.629
BRCA1	P38398-1.2	T1691R	Pathogenic	0.781
BRCA1	P38398-1.2	T1691S	Neutral	0.446
BRCA1	P38398-1.2	T1691V	Neutral	0.489
BRCA1	P38398-1.2	T1691W	Pathogenic	0.876
BRCA1	P38398-1.2	T1691Y	Pathogenic	0.816
BRCA1	P38398-1.2	D1692A	Pathogenic	0.7
BRCA1	P38398-1.2	D1692C	Pathogenic	0.685
BRCA1	P38398-1.2	D1692E	Neutral	0.326
BRCA1	P38398-1.2	D1692F	Pathogenic	0.836
BRCA1	P38398-1.2	D1692G	Pathogenic	0.713
BRCA1	P38398-1.2	D1692H	Pathogenic	0.635
BRCA1	P38398-1.2	D1692I	Pathogenic	0.799
BRCA1	P38398-1.2	D1692K	Pathogenic	0.72
BRCA1	P38398-1.2	D1692L	Pathogenic	0.852
BRCA1	P38398-1.2	D1692M	Pathogenic	0.801
BRCA1	P38398-1.2	D1692N	Neutral	0.343
BRCA1	P38398-1.2	D1692P	Neutral	0.491
BRCA1	P38398-1.2	D1692Q	Pathogenic	0.527
BRCA1	P38398-1.2	D1692R	Pathogenic	0.831
BRCA1	P38398-1.2	D1692S	Neutral	0.498
BRCA1	P38398-1.2	D1692T	Neutral	0.499
BRCA1	P38398-1.2	D1692V	Pathogenic	0.725
BRCA1	P38398-1.2	D1692W	Pathogenic	0.931
BRCA1	P38398-1.2	D1692Y	Pathogenic	0.855
BRCA1	P38398-1.2	A1693C	Neutral	0.198
BRCA1	P38398-1.2	A1693D	Neutral	0.362
BRCA1	P38398-1.2	A1693E	Neutral	0.371
BRCA1	P38398-1.2	A1693F	Pathogenic	0.6
BRCA1	P38398-1.2	A1693G	Neutral	0.199
BRCA1	P38398-1.2	A1693H	Pathogenic	0.513
BRCA1	P38398-1.2	A1693I	Neutral	0.449
BRCA1	P38398-1.2	A1693K	Pathogenic	0.511
BRCA1	P38398-1.2	A1693L	Neutral	0.45
BRCA1	P38398-1.2	A1693M	Neutral	0.452
BRCA1	P38398-1.2	A1693N	Neutral	0.389
BRCA1	P38398-1.2	A1693P	Neutral	0.281
BRCA1	P38398-1.2	A1693Q	Neutral	0.399
BRCA1	P38398-1.2	A1693R	Pathogenic	0.582
BRCA1	P38398-1.2	A1693S	Neutral	0.115
BRCA1	P38398-1.2	A1693T	Neutral	0.226
BRCA1	P38398-1.2	A1693V	Neutral	0.273
BRCA1	P38398-1.2	A1693W	Pathogenic	0.799
BRCA1	P38398-1.2	A1693Y	Pathogenic	0.635
BRCA1	P38398-1.2	E1694A	Neutral	0.433
BRCA1	P38398-1.2	E1694C	Pathogenic	0.595
BRCA1	P38398-1.2	E1694D	Neutral	0.132
BRCA1	P38398-1.2	E1694F	Pathogenic	0.518
BRCA1	P38398-1.2	E1694G	Pathogenic	0.627
BRCA1	P38398-1.2	E1694H	Neutral	0.204
BRCA1	P38398-1.2	E1694I	Neutral	0.457
BRCA1	P38398-1.2	E1694K	Neutral	0.207
BRCA1	P38398-1.2	E1694L	Neutral	0.458
BRCA1	P38398-1.2	E1694M	Neutral	0.372
BRCA1	P38398-1.2	E1694N	Neutral	0.221
BRCA1	P38398-1.2	E1694P	Neutral	0.312
BRCA1	P38398-1.2	E1694Q	Neutral	0.102
BRCA1	P38398-1.2	E1694R	Neutral	0.334
BRCA1	P38398-1.2	E1694S	Neutral	0.318
BRCA1	P38398-1.2	E1694T	Neutral	0.3
BRCA1	P38398-1.2	E1694V	Neutral	0.317
BRCA1	P38398-1.2	E1694W	Pathogenic	0.665
BRCA1	P38398-1.2	E1694Y	Neutral	0.465
BRCA1	P38398-1.2	F1695A	Pathogenic	0.792
BRCA1	P38398-1.2	F1695C	Pathogenic	0.717
BRCA1	P38398-1.2	F1695D	Pathogenic	0.759
BRCA1	P38398-1.2	F1695E	Pathogenic	0.68
BRCA1	P38398-1.2	F1695G	Pathogenic	0.893
BRCA1	P38398-1.2	F1695H	Neutral	0.46
BRCA1	P38398-1.2	F1695I	Neutral	0.348
BRCA1	P38398-1.2	F1695K	Pathogenic	0.542
BRCA1	P38398-1.2	F1695L	Neutral	0.348
BRCA1	P38398-1.2	F1695M	Neutral	0.346
BRCA1	P38398-1.2	F1695N	Pathogenic	0.739
BRCA1	P38398-1.2	F1695P	Pathogenic	0.827
BRCA1	P38398-1.2	F1695Q	Pathogenic	0.657
BRCA1	P38398-1.2	F1695R	Pathogenic	0.612
BRCA1	P38398-1.2	F1695S	Pathogenic	0.768
BRCA1	P38398-1.2	F1695T	Pathogenic	0.682
BRCA1	P38398-1.2	F1695V	Pathogenic	0.537
BRCA1	P38398-1.2	F1695W	Neutral	0.349
BRCA1	P38398-1.2	F1695Y	Neutral	0.136
BRCA1	P38398-1.2	V1696A	Pathogenic	0.74
BRCA1	P38398-1.2	V1696C	Pathogenic	0.732
BRCA1	P38398-1.2	V1696D	Pathogenic	0.83
BRCA1	P38398-1.2	V1696E	Pathogenic	0.731
BRCA1	P38398-1.2	V1696F	Pathogenic	0.776
BRCA1	P38398-1.2	V1696G	Pathogenic	0.928
BRCA1	P38398-1.2	V1696H	Pathogenic	0.829
BRCA1	P38398-1.2	V1696I	Neutral	0.387
BRCA1	P38398-1.2	V1696K	Pathogenic	0.828
BRCA1	P38398-1.2	V1696L	Pathogenic	0.567
BRCA1	P38398-1.2	V1696M	Pathogenic	0.569
BRCA1	P38398-1.2	V1696N	Pathogenic	0.814
BRCA1	P38398-1.2	V1696P	Pathogenic	0.781
BRCA1	P38398-1.2	V1696Q	Pathogenic	0.754
BRCA1	P38398-1.2	V1696R	Pathogenic	0.902
BRCA1	P38398-1.2	V1696S	Pathogenic	0.837
BRCA1	P38398-1.2	V1696T	Pathogenic	0.615
BRCA1	P38398-1.2	V1696W	Pathogenic	0.93
BRCA1	P38398-1.2	V1696Y	Pathogenic	0.799
BRCA1	P38398-1.2	C1697A	Pathogenic	0.776
BRCA1	P38398-1.2	C1697D	Pathogenic	0.881
BRCA1	P38398-1.2	C1697E	Pathogenic	0.941
BRCA1	P38398-1.2	C1697F	Pathogenic	0.933
BRCA1	P38398-1.2	C1697G	Pathogenic	0.94
BRCA1	P38398-1.2	C1697H	Pathogenic	0.932
BRCA1	P38398-1.2	C1697I	Pathogenic	0.884
BRCA1	P38398-1.2	C1697K	Pathogenic	0.952
BRCA1	P38398-1.2	C1697L	Pathogenic	0.884
BRCA1	P38398-1.2	C1697M	Pathogenic	0.885
BRCA1	P38398-1.2	C1697N	Pathogenic	0.893
BRCA1	P38398-1.2	C1697P	Pathogenic	0.882
BRCA1	P38398-1.2	C1697Q	Pathogenic	0.926
BRCA1	P38398-1.2	C1697R	Pathogenic	0.963
BRCA1	P38398-1.2	C1697S	Pathogenic	0.813
BRCA1	P38398-1.2	C1697T	Pathogenic	0.793
BRCA1	P38398-1.2	C1697V	Pathogenic	0.834
BRCA1	P38398-1.2	C1697W	Pathogenic	0.963
BRCA1	P38398-1.2	C1697Y	Pathogenic	0.942
BRCA1	P38398-1.2	E1698A	Pathogenic	0.599
BRCA1	P38398-1.2	E1698C	Pathogenic	0.743
BRCA1	P38398-1.2	E1698D	Neutral	0.23
BRCA1	P38398-1.2	E1698F	Pathogenic	0.678
BRCA1	P38398-1.2	E1698G	Pathogenic	0.768
BRCA1	P38398-1.2	E1698H	Neutral	0.334
BRCA1	P38398-1.2	E1698I	Pathogenic	0.623
BRCA1	P38398-1.2	E1698K	Neutral	0.339
BRCA1	P38398-1.2	E1698L	Pathogenic	0.623
BRCA1	P38398-1.2	E1698M	Pathogenic	0.537
BRCA1	P38398-1.2	E1698N	Neutral	0.357
BRCA1	P38398-1.2	E1698P	Neutral	0.471
BRCA1	P38398-1.2	E1698Q	Neutral	0.182
BRCA1	P38398-1.2	E1698R	Neutral	0.496
BRCA1	P38398-1.2	E1698S	Neutral	0.478
BRCA1	P38398-1.2	E1698T	Neutral	0.457
BRCA1	P38398-1.2	E1698V	Neutral	0.476
BRCA1	P38398-1.2	E1698W	Pathogenic	0.796
BRCA1	P38398-1.2	E1698Y	Pathogenic	0.63
BRCA1	P38398-1.2	R1699A	Pathogenic	0.925
BRCA1	P38398-1.2	R1699C	Pathogenic	0.943
BRCA1	P38398-1.2	R1699D	Pathogenic	0.914
BRCA1	P38398-1.2	R1699E	Pathogenic	0.775
BRCA1	P38398-1.2	R1699F	Pathogenic	0.846
BRCA1	P38398-1.2	R1699G	Pathogenic	0.965
BRCA1	P38398-1.2	R1699H	Pathogenic	0.735
BRCA1	P38398-1.2	R1699I	Pathogenic	0.875
BRCA1	P38398-1.2	R1699K	Neutral	0.484
BRCA1	P38398-1.2	R1699L	Pathogenic	0.83
BRCA1	P38398-1.2	R1699M	Pathogenic	0.774
BRCA1	P38398-1.2	R1699N	Pathogenic	0.821
BRCA1	P38398-1.2	R1699P	Pathogenic	0.914
BRCA1	P38398-1.2	R1699Q	Pathogenic	0.68
BRCA1	P38398-1.2	R1699S	Pathogenic	0.916
BRCA1	P38398-1.2	R1699T	Pathogenic	0.874
BRCA1	P38398-1.2	R1699V	Pathogenic	0.915
BRCA1	P38398-1.2	R1699W	Pathogenic	0.851
BRCA1	P38398-1.2	R1699Y	Pathogenic	0.773
BRCA1	P38398-1.2	T1700A	Pathogenic	0.694
BRCA1	P38398-1.2	T1700C	Pathogenic	0.679
BRCA1	P38398-1.2	T1700D	Pathogenic	0.653
BRCA1	P38398-1.2	T1700E	Pathogenic	0.72
BRCA1	P38398-1.2	T1700F	Pathogenic	0.867
BRCA1	P38398-1.2	T1700G	Pathogenic	0.877
BRCA1	P38398-1.2	T1700H	Pathogenic	0.821
BRCA1	P38398-1.2	T1700I	Pathogenic	0.78
BRCA1	P38398-1.2	T1700K	Pathogenic	0.82
BRCA1	P38398-1.2	T1700L	Pathogenic	0.78
BRCA1	P38398-1.2	T1700M	Pathogenic	0.782
BRCA1	P38398-1.2	T1700N	Pathogenic	0.573
BRCA1	P38398-1.2	T1700P	Pathogenic	0.66
BRCA1	P38398-1.2	T1700Q	Pathogenic	0.743
BRCA1	P38398-1.2	T1700R	Pathogenic	0.859
BRCA1	P38398-1.2	T1700S	Pathogenic	0.579
BRCA1	P38398-1.2	T1700V	Pathogenic	0.62
BRCA1	P38398-1.2	T1700W	Pathogenic	0.923
BRCA1	P38398-1.2	T1700Y	Pathogenic	0.883
BRCA1	P38398-1.2	L1701A	Pathogenic	0.794
BRCA1	P38398-1.2	L1701C	Pathogenic	0.719
BRCA1	P38398-1.2	L1701D	Pathogenic	0.868
BRCA1	P38398-1.2	L1701E	Pathogenic	0.755
BRCA1	P38398-1.2	L1701F	Neutral	0.497
BRCA1	P38398-1.2	L1701G	Pathogenic	0.946
BRCA1	P38398-1.2	L1701H	Pathogenic	0.719
BRCA1	P38398-1.2	L1701I	Neutral	0.272
BRCA1	P38398-1.2	L1701K	Pathogenic	0.66
BRCA1	P38398-1.2	L1701M	Neutral	0.27
BRCA1	P38398-1.2	L1701N	Pathogenic	0.804
BRCA1	P38398-1.2	L1701P	Pathogenic	0.828
BRCA1	P38398-1.2	L1701Q	Pathogenic	0.659
BRCA1	P38398-1.2	L1701R	Pathogenic	0.722
BRCA1	P38398-1.2	L1701S	Pathogenic	0.828
BRCA1	P38398-1.2	L1701T	Pathogenic	0.683
BRCA1	P38398-1.2	L1701V	Neutral	0.448
BRCA1	P38398-1.2	L1701W	Pathogenic	0.791
BRCA1	P38398-1.2	L1701Y	Pathogenic	0.616
BRCA1	P38398-1.2	K1702A	Pathogenic	0.876
BRCA1	P38398-1.2	K1702C	Pathogenic	0.905
BRCA1	P38398-1.2	K1702D	Pathogenic	0.809
BRCA1	P38398-1.2	K1702E	Pathogenic	0.578
BRCA1	P38398-1.2	K1702F	Pathogenic	0.759
BRCA1	P38398-1.2	K1702G	Pathogenic	0.94
BRCA1	P38398-1.2	K1702H	Pathogenic	0.696
BRCA1	P38398-1.2	K1702I	Pathogenic	0.801
BRCA1	P38398-1.2	K1702L	Pathogenic	0.736
BRCA1	P38398-1.2	K1702M	Pathogenic	0.662
BRCA1	P38398-1.2	K1702N	Pathogenic	0.724
BRCA1	P38398-1.2	K1702P	Pathogenic	0.808
BRCA1	P38398-1.2	K1702Q	Pathogenic	0.549
BRCA1	P38398-1.2	K1702R	Neutral	0.418
BRCA1	P38398-1.2	K1702S	Pathogenic	0.812
BRCA1	P38398-1.2	K1702T	Pathogenic	0.799
BRCA1	P38398-1.2	K1702V	Pathogenic	0.811
BRCA1	P38398-1.2	K1702W	Pathogenic	0.853
BRCA1	P38398-1.2	K1702Y	Pathogenic	0.717
BRCA1	P38398-1.2	Y1703A	Pathogenic	0.971
BRCA1	P38398-1.2	Y1703C	Pathogenic	0.956
BRCA1	P38398-1.2	Y1703D	Pathogenic	0.965
BRCA1	P38398-1.2	Y1703E	Pathogenic	0.927
BRCA1	P38398-1.2	Y1703F	Pathogenic	0.541
BRCA1	P38398-1.2	Y1703G	Pathogenic	0.986
BRCA1	P38398-1.2	Y1703H	Pathogenic	0.712
BRCA1	P38398-1.2	Y1703I	Pathogenic	0.866
BRCA1	P38398-1.2	Y1703K	Pathogenic	0.877
BRCA1	P38398-1.2	Y1703L	Pathogenic	0.866
BRCA1	P38398-1.2	Y1703M	Pathogenic	0.867
BRCA1	P38398-1.2	Y1703N	Pathogenic	0.945
BRCA1	P38398-1.2	Y1703P	Pathogenic	0.966
BRCA1	P38398-1.2	Y1703Q	Pathogenic	0.889
BRCA1	P38398-1.2	Y1703R	Pathogenic	0.879
BRCA1	P38398-1.2	Y1703S	Pathogenic	0.966
BRCA1	P38398-1.2	Y1703T	Pathogenic	0.949
BRCA1	P38398-1.2	Y1703V	Pathogenic	0.909
BRCA1	P38398-1.2	Y1703W	Pathogenic	0.705
BRCA1	P38398-1.2	F1704A	Pathogenic	0.952
BRCA1	P38398-1.2	F1704C	Pathogenic	0.929
BRCA1	P38398-1.2	F1704D	Pathogenic	0.942
BRCA1	P38398-1.2	F1704E	Pathogenic	0.916
BRCA1	P38398-1.2	F1704G	Pathogenic	0.977
BRCA1	P38398-1.2	F1704H	Pathogenic	0.814
BRCA1	P38398-1.2	F1704I	Pathogenic	0.733
BRCA1	P38398-1.2	F1704K	Pathogenic	0.859
BRCA1	P38398-1.2	F1704L	Pathogenic	0.733
BRCA1	P38398-1.2	F1704M	Pathogenic	0.731
BRCA1	P38398-1.2	F1704N	Pathogenic	0.936
BRCA1	P38398-1.2	F1704P	Pathogenic	0.961
BRCA1	P38398-1.2	F1704Q	Pathogenic	0.908
BRCA1	P38398-1.2	F1704R	Pathogenic	0.89
BRCA1	P38398-1.2	F1704S	Pathogenic	0.945
BRCA1	P38398-1.2	F1704T	Pathogenic	0.917
BRCA1	P38398-1.2	F1704V	Pathogenic	0.856
BRCA1	P38398-1.2	F1704W	Pathogenic	0.734
BRCA1	P38398-1.2	F1704Y	Neutral	0.448
BRCA1	P38398-1.2	L1705A	Pathogenic	0.803
BRCA1	P38398-1.2	L1705C	Pathogenic	0.73
BRCA1	P38398-1.2	L1705D	Pathogenic	0.874
BRCA1	P38398-1.2	L1705E	Pathogenic	0.765
BRCA1	P38398-1.2	L1705F	Pathogenic	0.511
BRCA1	P38398-1.2	L1705G	Pathogenic	0.948
BRCA1	P38398-1.2	L1705H	Pathogenic	0.73
BRCA1	P38398-1.2	L1705I	Neutral	0.283
BRCA1	P38398-1.2	L1705K	Pathogenic	0.673
BRCA1	P38398-1.2	L1705M	Neutral	0.281
BRCA1	P38398-1.2	L1705N	Pathogenic	0.813
BRCA1	P38398-1.2	L1705P	Pathogenic	0.836
BRCA1	P38398-1.2	L1705Q	Pathogenic	0.671
BRCA1	P38398-1.2	L1705R	Pathogenic	0.733
BRCA1	P38398-1.2	L1705S	Pathogenic	0.836
BRCA1	P38398-1.2	L1705T	Pathogenic	0.695
BRCA1	P38398-1.2	L1705V	Neutral	0.462
BRCA1	P38398-1.2	L1705W	Pathogenic	0.8
BRCA1	P38398-1.2	L1705Y	Pathogenic	0.629
BRCA1	P38398-1.2	G1706A	Pathogenic	0.688
BRCA1	P38398-1.2	G1706C	Pathogenic	0.908
BRCA1	P38398-1.2	G1706D	Pathogenic	0.843
BRCA1	P38398-1.2	G1706E	Pathogenic	0.92
BRCA1	P38398-1.2	G1706F	Pathogenic	0.967
BRCA1	P38398-1.2	G1706H	Pathogenic	0.934
BRCA1	P38398-1.2	G1706I	Pathogenic	0.97
BRCA1	P38398-1.2	G1706K	Pathogenic	0.953
BRCA1	P38398-1.2	G1706L	Pathogenic	0.97
BRCA1	P38398-1.2	G1706M	Pathogenic	0.958
BRCA1	P38398-1.2	G1706N	Pathogenic	0.807
BRCA1	P38398-1.2	G1706P	Pathogenic	0.883
BRCA1	P38398-1.2	G1706Q	Pathogenic	0.928
BRCA1	P38398-1.2	G1706R	Pathogenic	0.965
BRCA1	P38398-1.2	G1706S	Pathogenic	0.717
BRCA1	P38398-1.2	G1706T	Pathogenic	0.891
BRCA1	P38398-1.2	G1706V	Pathogenic	0.937
BRCA1	P38398-1.2	G1706W	Pathogenic	0.974
BRCA1	P38398-1.2	G1706Y	Pathogenic	0.971
BRCA1	P38398-1.2	I1707A	Pathogenic	0.886
BRCA1	P38398-1.2	I1707C	Pathogenic	0.837
BRCA1	P38398-1.2	I1707D	Pathogenic	0.902
BRCA1	P38398-1.2	I1707E	Pathogenic	0.861
BRCA1	P38398-1.2	I1707F	Pathogenic	0.666
BRCA1	P38398-1.2	I1707G	Pathogenic	0.972
BRCA1	P38398-1.2	I1707H	Pathogenic	0.837
BRCA1	P38398-1.2	I1707K	Pathogenic	0.849
BRCA1	P38398-1.2	I1707L	Neutral	0.429
BRCA1	P38398-1.2	I1707M	Pathogenic	0.517
BRCA1	P38398-1.2	I1707N	Pathogenic	0.892
BRCA1	P38398-1.2	I1707P	Pathogenic	0.906
BRCA1	P38398-1.2	I1707Q	Pathogenic	0.848
BRCA1	P38398-1.2	I1707R	Pathogenic	0.882
BRCA1	P38398-1.2	I1707S	Pathogenic	0.906
BRCA1	P38398-1.2	I1707T	Pathogenic	0.813
BRCA1	P38398-1.2	I1707V	Neutral	0.441
BRCA1	P38398-1.2	I1707W	Pathogenic	0.916
BRCA1	P38398-1.2	I1707Y	Pathogenic	0.763
BRCA1	P38398-1.2	A1708C	Pathogenic	0.683
BRCA1	P38398-1.2	A1708D	Pathogenic	0.832
BRCA1	P38398-1.2	A1708E	Pathogenic	0.837
BRCA1	P38398-1.2	A1708F	Pathogenic	0.929
BRCA1	P38398-1.2	A1708G	Pathogenic	0.684
BRCA1	P38398-1.2	A1708H	Pathogenic	0.901
BRCA1	P38398-1.2	A1708I	Pathogenic	0.876
BRCA1	P38398-1.2	A1708K	Pathogenic	0.901
BRCA1	P38398-1.2	A1708L	Pathogenic	0.876
BRCA1	P38398-1.2	A1708M	Pathogenic	0.877
BRCA1	P38398-1.2	A1708N	Pathogenic	0.847
BRCA1	P38398-1.2	A1708P	Pathogenic	0.773
BRCA1	P38398-1.2	A1708Q	Pathogenic	0.852
BRCA1	P38398-1.2	A1708R	Pathogenic	0.924
BRCA1	P38398-1.2	A1708S	Pathogenic	0.53
BRCA1	P38398-1.2	A1708T	Pathogenic	0.718
BRCA1	P38398-1.2	A1708V	Pathogenic	0.765
BRCA1	P38398-1.2	A1708W	Pathogenic	0.972
BRCA1	P38398-1.2	A1708Y	Pathogenic	0.938
BRCA1	P38398-1.2	G1709A	Pathogenic	0.628
BRCA1	P38398-1.2	G1709C	Pathogenic	0.883
BRCA1	P38398-1.2	G1709D	Pathogenic	0.804
BRCA1	P38398-1.2	G1709E	Pathogenic	0.898
BRCA1	P38398-1.2	G1709F	Pathogenic	0.957
BRCA1	P38398-1.2	G1709H	Pathogenic	0.916
BRCA1	P38398-1.2	G1709I	Pathogenic	0.961
BRCA1	P38398-1.2	G1709K	Pathogenic	0.94
BRCA1	P38398-1.2	G1709L	Pathogenic	0.962
BRCA1	P38398-1.2	G1709M	Pathogenic	0.946
BRCA1	P38398-1.2	G1709N	Pathogenic	0.762
BRCA1	P38398-1.2	G1709P	Pathogenic	0.853
BRCA1	P38398-1.2	G1709Q	Pathogenic	0.909
BRCA1	P38398-1.2	G1709R	Pathogenic	0.954
BRCA1	P38398-1.2	G1709S	Pathogenic	0.66
BRCA1	P38398-1.2	G1709T	Pathogenic	0.862
BRCA1	P38398-1.2	G1709V	Pathogenic	0.92
BRCA1	P38398-1.2	G1709W	Pathogenic	0.966
BRCA1	P38398-1.2	G1709Y	Pathogenic	0.963
BRCA1	P38398-1.2	G1710A	Pathogenic	0.59
BRCA1	P38398-1.2	G1710C	Pathogenic	0.866
BRCA1	P38398-1.2	G1710D	Pathogenic	0.777
BRCA1	P38398-1.2	G1710E	Pathogenic	0.883
BRCA1	P38398-1.2	G1710F	Pathogenic	0.95
BRCA1	P38398-1.2	G1710H	Pathogenic	0.903
BRCA1	P38398-1.2	G1710I	Pathogenic	0.955
BRCA1	P38398-1.2	G1710K	Pathogenic	0.93
BRCA1	P38398-1.2	G1710L	Pathogenic	0.955
BRCA1	P38398-1.2	G1710M	Pathogenic	0.937
BRCA1	P38398-1.2	G1710N	Pathogenic	0.731
BRCA1	P38398-1.2	G1710P	Pathogenic	0.831
BRCA1	P38398-1.2	G1710Q	Pathogenic	0.894
BRCA1	P38398-1.2	G1710R	Pathogenic	0.947
BRCA1	P38398-1.2	G1710S	Pathogenic	0.623
BRCA1	P38398-1.2	G1710T	Pathogenic	0.841
BRCA1	P38398-1.2	G1710V	Pathogenic	0.907
BRCA1	P38398-1.2	G1710W	Pathogenic	0.96
BRCA1	P38398-1.2	G1710Y	Pathogenic	0.956
BRCA1	P38398-1.2	K1711A	Pathogenic	0.753
BRCA1	P38398-1.2	K1711C	Pathogenic	0.804
BRCA1	P38398-1.2	K1711D	Pathogenic	0.646
BRCA1	P38398-1.2	K1711E	Neutral	0.371
BRCA1	P38398-1.2	K1711F	Pathogenic	0.576
BRCA1	P38398-1.2	K1711G	Pathogenic	0.871
BRCA1	P38398-1.2	K1711H	Neutral	0.497
BRCA1	P38398-1.2	K1711I	Pathogenic	0.634
BRCA1	P38398-1.2	K1711L	Pathogenic	0.547
BRCA1	P38398-1.2	K1711M	Neutral	0.458
BRCA1	P38398-1.2	K1711N	Pathogenic	0.531
BRCA1	P38398-1.2	K1711P	Pathogenic	0.645
BRCA1	P38398-1.2	K1711Q	Neutral	0.344
BRCA1	P38398-1.2	K1711R	Neutral	0.236
BRCA1	P38398-1.2	K1711S	Pathogenic	0.651
BRCA1	P38398-1.2	K1711T	Pathogenic	0.632
BRCA1	P38398-1.2	K1711V	Pathogenic	0.65
BRCA1	P38398-1.2	K1711W	Pathogenic	0.715
BRCA1	P38398-1.2	K1711Y	Pathogenic	0.522
BRCA1	P38398-1.2	W1712A	Pathogenic	0.993
BRCA1	P38398-1.2	W1712C	Pathogenic	0.985
BRCA1	P38398-1.2	W1712D	Pathogenic	0.991
BRCA1	P38398-1.2	W1712E	Pathogenic	0.982
BRCA1	P38398-1.2	W1712F	Pathogenic	0.881
BRCA1	P38398-1.2	W1712G	Pathogenic	0.993
BRCA1	P38398-1.2	W1712H	Pathogenic	0.969
BRCA1	P38398-1.2	W1712I	Pathogenic	0.976
BRCA1	P38398-1.2	W1712K	Pathogenic	0.968
BRCA1	P38398-1.2	W1712L	Pathogenic	0.966
BRCA1	P38398-1.2	W1712M	Pathogenic	0.951
BRCA1	P38398-1.2	W1712N	Pathogenic	0.99
BRCA1	P38398-1.2	W1712P	Pathogenic	0.992
BRCA1	P38398-1.2	W1712Q	Pathogenic	0.971
BRCA1	P38398-1.2	W1712R	Pathogenic	0.958
BRCA1	P38398-1.2	W1712S	Pathogenic	0.992
BRCA1	P38398-1.2	W1712T	Pathogenic	0.982
BRCA1	P38398-1.2	W1712V	Pathogenic	0.984
BRCA1	P38398-1.2	W1712Y	Pathogenic	0.816
BRCA1	P38398-1.2	V1713A	Neutral	0.345
BRCA1	P38398-1.2	V1713C	Neutral	0.335
BRCA1	P38398-1.2	V1713D	Neutral	0.475
BRCA1	P38398-1.2	V1713E	Neutral	0.335
BRCA1	P38398-1.2	V1713F	Neutral	0.39
BRCA1	P38398-1.2	V1713G	Pathogenic	0.704
BRCA1	P38398-1.2	V1713H	Neutral	0.473
BRCA1	P38398-1.2	V1713I	Neutral	0.105
BRCA1	P38398-1.2	V1713K	Neutral	0.471
BRCA1	P38398-1.2	V1713L	Neutral	0.195
BRCA1	P38398-1.2	V1713M	Neutral	0.196
BRCA1	P38398-1.2	V1713N	Neutral	0.448
BRCA1	P38398-1.2	V1713P	Neutral	0.398
BRCA1	P38398-1.2	V1713Q	Neutral	0.362
BRCA1	P38398-1.2	V1713R	Pathogenic	0.631
BRCA1	P38398-1.2	V1713S	Neutral	0.487
BRCA1	P38398-1.2	V1713T	Neutral	0.228
BRCA1	P38398-1.2	V1713W	Pathogenic	0.71
BRCA1	P38398-1.2	V1713Y	Neutral	0.424
BRCA1	P38398-1.2	V1714A	Pathogenic	0.754
BRCA1	P38398-1.2	V1714C	Pathogenic	0.745
BRCA1	P38398-1.2	V1714D	Pathogenic	0.84
BRCA1	P38398-1.2	V1714E	Pathogenic	0.745
BRCA1	P38398-1.2	V1714F	Pathogenic	0.788
BRCA1	P38398-1.2	V1714G	Pathogenic	0.933
BRCA1	P38398-1.2	V1714H	Pathogenic	0.839
BRCA1	P38398-1.2	V1714I	Neutral	0.404
BRCA1	P38398-1.2	V1714K	Pathogenic	0.838
BRCA1	P38398-1.2	V1714L	Pathogenic	0.585
BRCA1	P38398-1.2	V1714M	Pathogenic	0.587
BRCA1	P38398-1.2	V1714N	Pathogenic	0.825
BRCA1	P38398-1.2	V1714P	Pathogenic	0.793
BRCA1	P38398-1.2	V1714Q	Pathogenic	0.767
BRCA1	P38398-1.2	V1714R	Pathogenic	0.909
BRCA1	P38398-1.2	V1714S	Pathogenic	0.847
BRCA1	P38398-1.2	V1714T	Pathogenic	0.632
BRCA1	P38398-1.2	V1714W	Pathogenic	0.934
BRCA1	P38398-1.2	V1714Y	Pathogenic	0.81
BRCA1	P38398-1.2	S1715A	Neutral	0.393
BRCA1	P38398-1.2	S1715C	Pathogenic	0.607
BRCA1	P38398-1.2	S1715D	Pathogenic	0.547
BRCA1	P38398-1.2	S1715E	Pathogenic	0.643
BRCA1	P38398-1.2	S1715F	Pathogenic	0.867
BRCA1	P38398-1.2	S1715G	Pathogenic	0.588
BRCA1	P38398-1.2	S1715H	Pathogenic	0.762
BRCA1	P38398-1.2	S1715I	Pathogenic	0.836
BRCA1	P38398-1.2	S1715K	Pathogenic	0.761
BRCA1	P38398-1.2	S1715L	Pathogenic	0.836
BRCA1	P38398-1.2	S1715M	Pathogenic	0.781
BRCA1	P38398-1.2	S1715N	Neutral	0.484
BRCA1	P38398-1.2	S1715P	Pathogenic	0.629
BRCA1	P38398-1.2	S1715Q	Pathogenic	0.67
BRCA1	P38398-1.2	S1715R	Pathogenic	0.86
BRCA1	P38398-1.2	S1715T	Neutral	0.469
BRCA1	P38398-1.2	S1715V	Pathogenic	0.771
BRCA1	P38398-1.2	S1715W	Pathogenic	0.945
BRCA1	P38398-1.2	S1715Y	Pathogenic	0.883
BRCA1	P38398-1.2	Y1716A	Pathogenic	0.933
BRCA1	P38398-1.2	Y1716C	Pathogenic	0.903
BRCA1	P38398-1.2	Y1716D	Pathogenic	0.92
BRCA1	P38398-1.2	Y1716E	Pathogenic	0.844
BRCA1	P38398-1.2	Y1716F	Neutral	0.332
BRCA1	P38398-1.2	Y1716G	Pathogenic	0.968
BRCA1	P38398-1.2	Y1716H	Pathogenic	0.511
BRCA1	P38398-1.2	Y1716I	Pathogenic	0.732
BRCA1	P38398-1.2	Y1716K	Pathogenic	0.75
BRCA1	P38398-1.2	Y1716L	Pathogenic	0.732
BRCA1	P38398-1.2	Y1716M	Pathogenic	0.734
BRCA1	P38398-1.2	Y1716N	Pathogenic	0.878
BRCA1	P38398-1.2	Y1716P	Pathogenic	0.924
BRCA1	P38398-1.2	Y1716Q	Pathogenic	0.772
BRCA1	P38398-1.2	Y1716R	Pathogenic	0.755
BRCA1	P38398-1.2	Y1716S	Pathogenic	0.924
BRCA1	P38398-1.2	Y1716T	Pathogenic	0.887
BRCA1	P38398-1.2	Y1716V	Pathogenic	0.808
BRCA1	P38398-1.2	Y1716W	Pathogenic	0.503
BRCA1	P38398-1.2	F1717A	Pathogenic	0.569
BRCA1	P38398-1.2	F1717C	Neutral	0.468
BRCA1	P38398-1.2	F1717D	Pathogenic	0.522
BRCA1	P38398-1.2	F1717E	Neutral	0.424
BRCA1	P38398-1.2	F1717G	Pathogenic	0.742
BRCA1	P38398-1.2	F1717H	Neutral	0.228
BRCA1	P38398-1.2	F1717I	Neutral	0.156
BRCA1	P38398-1.2	F1717K	Neutral	0.291
BRCA1	P38398-1.2	F1717L	Neutral	0.156
BRCA1	P38398-1.2	F1717M	Neutral	0.155
BRCA1	P38398-1.2	F1717N	Neutral	0.495
BRCA1	P38398-1.2	F1717P	Pathogenic	0.623
BRCA1	P38398-1.2	F1717Q	Neutral	0.399
BRCA1	P38398-1.2	F1717R	Neutral	0.353
BRCA1	P38398-1.2	F1717S	Pathogenic	0.535
BRCA1	P38398-1.2	F1717T	Neutral	0.426
BRCA1	P38398-1.2	F1717V	Neutral	0.287
BRCA1	P38398-1.2	F1717W	Neutral	0.157
BRCA1	P38398-1.2	F1717Y	Neutral	0.052
BRCA1	P38398-1.2	W1718A	Pathogenic	0.991
BRCA1	P38398-1.2	W1718C	Pathogenic	0.981
BRCA1	P38398-1.2	W1718D	Pathogenic	0.989
BRCA1	P38398-1.2	W1718E	Pathogenic	0.978
BRCA1	P38398-1.2	W1718F	Pathogenic	0.857
BRCA1	P38398-1.2	W1718G	Pathogenic	0.992
BRCA1	P38398-1.2	W1718H	Pathogenic	0.962
BRCA1	P38398-1.2	W1718I	Pathogenic	0.971
BRCA1	P38398-1.2	W1718K	Pathogenic	0.961
BRCA1	P38398-1.2	W1718L	Pathogenic	0.958
BRCA1	P38398-1.2	W1718M	Pathogenic	0.94
BRCA1	P38398-1.2	W1718N	Pathogenic	0.988
BRCA1	P38398-1.2	W1718P	Pathogenic	0.99
BRCA1	P38398-1.2	W1718Q	Pathogenic	0.965
BRCA1	P38398-1.2	W1718R	Pathogenic	0.948
BRCA1	P38398-1.2	W1718S	Pathogenic	0.99
BRCA1	P38398-1.2	W1718T	Pathogenic	0.978
BRCA1	P38398-1.2	W1718V	Pathogenic	0.98
BRCA1	P38398-1.2	W1718Y	Pathogenic	0.783
BRCA1	P38398-1.2	V1719A	Pathogenic	0.769
BRCA1	P38398-1.2	V1719C	Pathogenic	0.761
BRCA1	P38398-1.2	V1719D	Pathogenic	0.851
BRCA1	P38398-1.2	V1719E	Pathogenic	0.761
BRCA1	P38398-1.2	V1719F	Pathogenic	0.801
BRCA1	P38398-1.2	V1719G	Pathogenic	0.938
BRCA1	P38398-1.2	V1719H	Pathogenic	0.85
BRCA1	P38398-1.2	V1719I	Neutral	0.424
BRCA1	P38398-1.2	V1719K	Pathogenic	0.849
BRCA1	P38398-1.2	V1719L	Pathogenic	0.604
BRCA1	P38398-1.2	V1719M	Pathogenic	0.606
BRCA1	P38398-1.2	V1719N	Pathogenic	0.836
BRCA1	P38398-1.2	V1719P	Pathogenic	0.806
BRCA1	P38398-1.2	V1719Q	Pathogenic	0.782
BRCA1	P38398-1.2	V1719R	Pathogenic	0.915
BRCA1	P38398-1.2	V1719S	Pathogenic	0.857
BRCA1	P38398-1.2	V1719T	Pathogenic	0.651
BRCA1	P38398-1.2	V1719W	Pathogenic	0.939
BRCA1	P38398-1.2	V1719Y	Pathogenic	0.822
BRCA1	P38398-1.2	T1720A	Neutral	0.17
BRCA1	P38398-1.2	T1720C	Neutral	0.16
BRCA1	P38398-1.2	T1720D	Neutral	0.145
BRCA1	P38398-1.2	T1720E	Neutral	0.188
BRCA1	P38398-1.2	T1720F	Neutral	0.37
BRCA1	P38398-1.2	T1720G	Neutral	0.391
BRCA1	P38398-1.2	T1720H	Neutral	0.293
BRCA1	P38398-1.2	T1720I	Neutral	0.242
BRCA1	P38398-1.2	T1720K	Neutral	0.291
BRCA1	P38398-1.2	T1720L	Neutral	0.242
BRCA1	P38398-1.2	T1720M	Neutral	0.244
BRCA1	P38398-1.2	T1720N	Neutral	0.108
BRCA1	P38398-1.2	T1720P	Neutral	0.149
BRCA1	P38398-1.2	T1720Q	Neutral	0.207
BRCA1	P38398-1.2	T1720R	Neutral	0.354
BRCA1	P38398-1.2	T1720S	Neutral	0.11
BRCA1	P38398-1.2	T1720V	Neutral	0.128
BRCA1	P38398-1.2	T1720W	Pathogenic	0.52
BRCA1	P38398-1.2	T1720Y	Neutral	0.405
BRCA1	P38398-1.2	Q1721A	Pathogenic	0.634
BRCA1	P38398-1.2	Q1721C	Pathogenic	0.699
BRCA1	P38398-1.2	Q1721D	Neutral	0.414
BRCA1	P38398-1.2	Q1721E	Neutral	0.186
BRCA1	P38398-1.2	Q1721F	Pathogenic	0.662
BRCA1	P38398-1.2	Q1721G	Pathogenic	0.793
BRCA1	P38398-1.2	Q1721H	Neutral	0.317
BRCA1	P38398-1.2	Q1721I	Pathogenic	0.605
BRCA1	P38398-1.2	Q1721K	Neutral	0.318
BRCA1	P38398-1.2	Q1721L	Pathogenic	0.516
BRCA1	P38398-1.2	Q1721M	Neutral	0.342
BRCA1	P38398-1.2	Q1721N	Neutral	0.388
BRCA1	P38398-1.2	Q1721P	Pathogenic	0.507
BRCA1	P38398-1.2	Q1721R	Neutral	0.384
BRCA1	P38398-1.2	Q1721S	Pathogenic	0.514
BRCA1	P38398-1.2	Q1721T	Neutral	0.493
BRCA1	P38398-1.2	Q1721V	Pathogenic	0.513
BRCA1	P38398-1.2	Q1721W	Pathogenic	0.715
BRCA1	P38398-1.2	Q1721Y	Pathogenic	0.523
BRCA1	P38398-1.2	S1722A	Neutral	0.412
BRCA1	P38398-1.2	S1722C	Pathogenic	0.626
BRCA1	P38398-1.2	S1722D	Pathogenic	0.567
BRCA1	P38398-1.2	S1722E	Pathogenic	0.662
BRCA1	P38398-1.2	S1722F	Pathogenic	0.876
BRCA1	P38398-1.2	S1722G	Pathogenic	0.608
BRCA1	P38398-1.2	S1722H	Pathogenic	0.776
BRCA1	P38398-1.2	S1722I	Pathogenic	0.847
BRCA1	P38398-1.2	S1722K	Pathogenic	0.776
BRCA1	P38398-1.2	S1722L	Pathogenic	0.847
BRCA1	P38398-1.2	S1722M	Pathogenic	0.795
BRCA1	P38398-1.2	S1722N	Pathogenic	0.505
BRCA1	P38398-1.2	S1722P	Pathogenic	0.648
BRCA1	P38398-1.2	S1722Q	Pathogenic	0.688
BRCA1	P38398-1.2	S1722R	Pathogenic	0.869
BRCA1	P38398-1.2	S1722T	Neutral	0.489
BRCA1	P38398-1.2	S1722V	Pathogenic	0.785
BRCA1	P38398-1.2	S1722W	Pathogenic	0.949
BRCA1	P38398-1.2	S1722Y	Pathogenic	0.891
BRCA1	P38398-1.2	I1723A	Neutral	0.22
BRCA1	P38398-1.2	I1723C	Neutral	0.158
BRCA1	P38398-1.2	I1723D	Neutral	0.252
BRCA1	P38398-1.2	I1723E	Neutral	0.185
BRCA1	P38398-1.2	I1723F	Neutral	0.068
BRCA1	P38398-1.2	I1723G	Pathogenic	0.561
BRCA1	P38398-1.2	I1723H	Neutral	0.158
BRCA1	P38398-1.2	I1723K	Neutral	0.171
BRCA1	P38398-1.2	I1723L	Neutral	0.027
BRCA1	P38398-1.2	I1723M	Neutral	0.038
BRCA1	P38398-1.2	I1723N	Neutral	0.232
BRCA1	P38398-1.2	I1723P	Neutral	0.262
BRCA1	P38398-1.2	I1723Q	Neutral	0.17
BRCA1	P38398-1.2	I1723R	Neutral	0.215
BRCA1	P38398-1.2	I1723S	Neutral	0.261
BRCA1	P38398-1.2	I1723T	Neutral	0.137
BRCA1	P38398-1.2	I1723V	Neutral	0.028
BRCA1	P38398-1.2	I1723W	Neutral	0.286
BRCA1	P38398-1.2	I1723Y	Neutral	0.105
BRCA1	P38398-1.2	K1724A	Pathogenic	0.612
BRCA1	P38398-1.2	K1724C	Pathogenic	0.679
BRCA1	P38398-1.2	K1724D	Neutral	0.486
BRCA1	P38398-1.2	K1724E	Neutral	0.234
BRCA1	P38398-1.2	K1724F	Neutral	0.412
BRCA1	P38398-1.2	K1724G	Pathogenic	0.777
BRCA1	P38398-1.2	K1724H	Neutral	0.338
BRCA1	P38398-1.2	K1724I	Neutral	0.472
BRCA1	P38398-1.2	K1724L	Neutral	0.384
BRCA1	P38398-1.2	K1724M	Neutral	0.304
BRCA1	P38398-1.2	K1724N	Neutral	0.369
BRCA1	P38398-1.2	K1724P	Neutral	0.484
BRCA1	P38398-1.2	K1724Q	Neutral	0.213
BRCA1	P38398-1.2	K1724R	Neutral	0.138
BRCA1	P38398-1.2	K1724S	Neutral	0.491
BRCA1	P38398-1.2	K1724T	Neutral	0.47
BRCA1	P38398-1.2	K1724V	Neutral	0.489
BRCA1	P38398-1.2	K1724W	Pathogenic	0.564
BRCA1	P38398-1.2	K1724Y	Neutral	0.361
BRCA1	P38398-1.2	E1725A	Pathogenic	0.552
BRCA1	P38398-1.2	E1725C	Pathogenic	0.704
BRCA1	P38398-1.2	E1725D	Neutral	0.198
BRCA1	P38398-1.2	E1725F	Pathogenic	0.635
BRCA1	P38398-1.2	E1725G	Pathogenic	0.732
BRCA1	P38398-1.2	E1725H	Neutral	0.293
BRCA1	P38398-1.2	E1725I	Pathogenic	0.577
BRCA1	P38398-1.2	E1725K	Neutral	0.297
BRCA1	P38398-1.2	E1725L	Pathogenic	0.577
BRCA1	P38398-1.2	E1725M	Neutral	0.489
BRCA1	P38398-1.2	E1725N	Neutral	0.314
BRCA1	P38398-1.2	E1725P	Neutral	0.424
BRCA1	P38398-1.2	E1725Q	Neutral	0.155
BRCA1	P38398-1.2	E1725R	Neutral	0.448
BRCA1	P38398-1.2	E1725S	Neutral	0.43
BRCA1	P38398-1.2	E1725T	Neutral	0.409
BRCA1	P38398-1.2	E1725V	Neutral	0.429
BRCA1	P38398-1.2	E1725W	Pathogenic	0.763
BRCA1	P38398-1.2	E1725Y	Pathogenic	0.584
BRCA1	P38398-1.2	R1726A	Neutral	0.483
BRCA1	P38398-1.2	R1726C	Pathogenic	0.556
BRCA1	P38398-1.2	R1726D	Neutral	0.446
BRCA1	P38398-1.2	R1726E	Neutral	0.206
BRCA1	P38398-1.2	R1726F	Neutral	0.293
BRCA1	P38398-1.2	R1726G	Pathogenic	0.673
BRCA1	P38398-1.2	R1726H	Neutral	0.173
BRCA1	P38398-1.2	R1726I	Neutral	0.346
BRCA1	P38398-1.2	R1726K	Neutral	0.066
BRCA1	P38398-1.2	R1726L	Neutral	0.269
BRCA1	P38398-1.2	R1726M	Neutral	0.205
BRCA1	P38398-1.2	R1726N	Neutral	0.257
BRCA1	P38398-1.2	R1726P	Neutral	0.444
BRCA1	P38398-1.2	R1726Q	Neutral	0.138
BRCA1	P38398-1.2	R1726S	Neutral	0.451
BRCA1	P38398-1.2	R1726T	Neutral	0.344
BRCA1	P38398-1.2	R1726V	Neutral	0.45
BRCA1	P38398-1.2	R1726W	Neutral	0.301
BRCA1	P38398-1.2	R1726Y	Neutral	0.204
BRCA1	P38398-1.2	K1727A	Neutral	0.408
BRCA1	P38398-1.2	K1727C	Neutral	0.48
BRCA1	P38398-1.2	K1727D	Neutral	0.292
BRCA1	P38398-1.2	K1727E	Neutral	0.117
BRCA1	P38398-1.2	K1727F	Neutral	0.234
BRCA1	P38398-1.2	K1727G	Pathogenic	0.603
BRCA1	P38398-1.2	K1727H	Neutral	0.182
BRCA1	P38398-1.2	K1727I	Neutral	0.281
BRCA1	P38398-1.2	K1727L	Neutral	0.214
BRCA1	P38398-1.2	K1727M	Neutral	0.16
BRCA1	P38398-1.2	K1727N	Neutral	0.204
BRCA1	P38398-1.2	K1727P	Neutral	0.291
BRCA1	P38398-1.2	K1727Q	Neutral	0.106
BRCA1	P38398-1.2	K1727R	Neutral	0.065
BRCA1	P38398-1.2	K1727S	Neutral	0.296
BRCA1	P38398-1.2	K1727T	Neutral	0.279
BRCA1	P38398-1.2	K1727V	Neutral	0.295
BRCA1	P38398-1.2	K1727W	Neutral	0.361
BRCA1	P38398-1.2	K1727Y	Neutral	0.198
BRCA1	P38398-1.2	M1728A	Neutral	0.132
BRCA1	P38398-1.2	M1728C	Neutral	0.092
BRCA1	P38398-1.2	M1728D	Neutral	0.153
BRCA1	P38398-1.2	M1728E	Neutral	0.078
BRCA1	P38398-1.2	M1728F	Neutral	0.037
BRCA1	P38398-1.2	M1728G	Neutral	0.323
BRCA1	P38398-1.2	M1728H	Neutral	0.066
BRCA1	P38398-1.2	M1728I	Neutral	0.02
BRCA1	P38398-1.2	M1728K	Neutral	0.051
BRCA1	P38398-1.2	M1728L	Neutral	0.014
BRCA1	P38398-1.2	M1728N	Neutral	0.101
BRCA1	P38398-1.2	M1728P	Neutral	0.117
BRCA1	P38398-1.2	M1728Q	Neutral	0.035
BRCA1	P38398-1.2	M1728R	Neutral	0.066
BRCA1	P38398-1.2	M1728S	Neutral	0.117
BRCA1	P38398-1.2	M1728T	Neutral	0.079
BRCA1	P38398-1.2	M1728V	Neutral	0.031
BRCA1	P38398-1.2	M1728W	Neutral	0.092
BRCA1	P38398-1.2	M1728Y	Neutral	0.06
BRCA1	P38398-1.2	L1729A	Pathogenic	0.852
BRCA1	P38398-1.2	L1729C	Pathogenic	0.793
BRCA1	P38398-1.2	L1729D	Pathogenic	0.908
BRCA1	P38398-1.2	L1729E	Pathogenic	0.822
BRCA1	P38398-1.2	L1729F	Pathogenic	0.596
BRCA1	P38398-1.2	L1729G	Pathogenic	0.963
BRCA1	P38398-1.2	L1729H	Pathogenic	0.793
BRCA1	P38398-1.2	L1729I	Neutral	0.358
BRCA1	P38398-1.2	L1729K	Pathogenic	0.744
BRCA1	P38398-1.2	L1729M	Neutral	0.357
BRCA1	P38398-1.2	L1729N	Pathogenic	0.86
BRCA1	P38398-1.2	L1729P	Pathogenic	0.878
BRCA1	P38398-1.2	L1729Q	Pathogenic	0.743
BRCA1	P38398-1.2	L1729R	Pathogenic	0.795
BRCA1	P38398-1.2	L1729S	Pathogenic	0.878
BRCA1	P38398-1.2	L1729T	Pathogenic	0.764
BRCA1	P38398-1.2	L1729V	Pathogenic	0.549
BRCA1	P38398-1.2	L1729W	Pathogenic	0.85
BRCA1	P38398-1.2	L1729Y	Pathogenic	0.706
BRCA1	P38398-1.2	N1730A	Neutral	0.086
BRCA1	P38398-1.2	N1730C	Neutral	0.081
BRCA1	P38398-1.2	N1730D	Neutral	0.019
BRCA1	P38398-1.2	N1730E	Neutral	0.032
BRCA1	P38398-1.2	N1730F	Neutral	0.142
BRCA1	P38398-1.2	N1730G	Neutral	0.065
BRCA1	P38398-1.2	N1730H	Neutral	0.027
BRCA1	P38398-1.2	N1730I	Neutral	0.115
BRCA1	P38398-1.2	N1730K	Neutral	0.054
BRCA1	P38398-1.2	N1730L	Neutral	0.115
BRCA1	P38398-1.2	N1730M	Neutral	0.083
BRCA1	P38398-1.2	N1730P	Neutral	0.053
BRCA1	P38398-1.2	N1730Q	Neutral	0.035
BRCA1	P38398-1.2	N1730R	Neutral	0.071
BRCA1	P38398-1.2	N1730S	Neutral	0.027
BRCA1	P38398-1.2	N1730T	Neutral	0.025
BRCA1	P38398-1.2	N1730V	Neutral	0.079
BRCA1	P38398-1.2	N1730W	Neutral	0.305
BRCA1	P38398-1.2	N1730Y	Neutral	0.118
BRCA1	P38398-1.2	E1731A	Pathogenic	0.52
BRCA1	P38398-1.2	E1731C	Pathogenic	0.677
BRCA1	P38398-1.2	E1731D	Neutral	0.178
BRCA1	P38398-1.2	E1731F	Pathogenic	0.605
BRCA1	P38398-1.2	E1731G	Pathogenic	0.705
BRCA1	P38398-1.2	E1731H	Neutral	0.267
BRCA1	P38398-1.2	E1731I	Pathogenic	0.545
BRCA1	P38398-1.2	E1731K	Neutral	0.271
BRCA1	P38398-1.2	E1731L	Pathogenic	0.546
BRCA1	P38398-1.2	E1731M	Neutral	0.457
BRCA1	P38398-1.2	E1731N	Neutral	0.287
BRCA1	P38398-1.2	E1731P	Neutral	0.392
BRCA1	P38398-1.2	E1731Q	Neutral	0.139
BRCA1	P38398-1.2	E1731R	Neutral	0.416
BRCA1	P38398-1.2	E1731S	Neutral	0.399
BRCA1	P38398-1.2	E1731T	Neutral	0.379
BRCA1	P38398-1.2	E1731V	Neutral	0.397
BRCA1	P38398-1.2	E1731W	Pathogenic	0.739
BRCA1	P38398-1.2	E1731Y	Pathogenic	0.552
BRCA1	P38398-1.2	H1732A	Neutral	0.215
BRCA1	P38398-1.2	H1732C	Neutral	0.204
BRCA1	P38398-1.2	H1732D	Neutral	0.099
BRCA1	P38398-1.2	H1732E	Neutral	0.049
BRCA1	P38398-1.2	H1732F	Neutral	0.08
BRCA1	P38398-1.2	H1732G	Neutral	0.295
BRCA1	P38398-1.2	H1732I	Neutral	0.124
BRCA1	P38398-1.2	H1732K	Neutral	0.081
BRCA1	P38398-1.2	H1732L	Neutral	0.124
BRCA1	P38398-1.2	H1732M	Neutral	0.09
BRCA1	P38398-1.2	H1732N	Neutral	0.046
BRCA1	P38398-1.2	H1732P	Neutral	0.14
BRCA1	P38398-1.2	H1732Q	Neutral	0.044
BRCA1	P38398-1.2	H1732R	Neutral	0.075
BRCA1	P38398-1.2	H1732S	Neutral	0.143
BRCA1	P38398-1.2	H1732T	Neutral	0.134
BRCA1	P38398-1.2	H1732V	Neutral	0.143
BRCA1	P38398-1.2	H1732W	Neutral	0.188
BRCA1	P38398-1.2	H1732Y	Neutral	0.033
BRCA1	P38398-1.2	D1733A	Neutral	0.1
BRCA1	P38398-1.2	D1733C	Neutral	0.094
BRCA1	P38398-1.2	D1733E	Neutral	0.023
BRCA1	P38398-1.2	D1733F	Neutral	0.195
BRCA1	P38398-1.2	D1733G	Neutral	0.106
BRCA1	P38398-1.2	D1733H	Neutral	0.076
BRCA1	P38398-1.2	D1733I	Neutral	0.159
BRCA1	P38398-1.2	D1733K	Neutral	0.109
BRCA1	P38398-1.2	D1733L	Neutral	0.215
BRCA1	P38398-1.2	D1733M	Neutral	0.161
BRCA1	P38398-1.2	D1733N	Neutral	0.024
BRCA1	P38398-1.2	D1733P	Neutral	0.044
BRCA1	P38398-1.2	D1733Q	Neutral	0.05
BRCA1	P38398-1.2	D1733R	Neutral	0.19
BRCA1	P38398-1.2	D1733S	Neutral	0.045
BRCA1	P38398-1.2	D1733T	Neutral	0.045
BRCA1	P38398-1.2	D1733V	Neutral	0.112
BRCA1	P38398-1.2	D1733W	Neutral	0.392
BRCA1	P38398-1.2	D1733Y	Neutral	0.22
BRCA1	P38398-1.2	F1734A	Pathogenic	0.871
BRCA1	P38398-1.2	F1734C	Pathogenic	0.817
BRCA1	P38398-1.2	F1734D	Pathogenic	0.848
BRCA1	P38398-1.2	F1734E	Pathogenic	0.789
BRCA1	P38398-1.2	F1734G	Pathogenic	0.936
BRCA1	P38398-1.2	F1734H	Pathogenic	0.6
BRCA1	P38398-1.2	F1734I	Neutral	0.485
BRCA1	P38398-1.2	F1734K	Pathogenic	0.676
BRCA1	P38398-1.2	F1734L	Neutral	0.485
BRCA1	P38398-1.2	F1734M	Neutral	0.482
BRCA1	P38398-1.2	F1734N	Pathogenic	0.833
BRCA1	P38398-1.2	F1734P	Pathogenic	0.894
BRCA1	P38398-1.2	F1734Q	Pathogenic	0.771
BRCA1	P38398-1.2	F1734R	Pathogenic	0.735
BRCA1	P38398-1.2	F1734S	Pathogenic	0.854
BRCA1	P38398-1.2	F1734T	Pathogenic	0.79
BRCA1	P38398-1.2	F1734V	Pathogenic	0.671
BRCA1	P38398-1.2	F1734W	Neutral	0.486
BRCA1	P38398-1.2	F1734Y	Neutral	0.218
BRCA1	P38398-1.2	E1735A	Pathogenic	0.557
BRCA1	P38398-1.2	E1735C	Pathogenic	0.708
BRCA1	P38398-1.2	E1735D	Neutral	0.201
BRCA1	P38398-1.2	E1735F	Pathogenic	0.639
BRCA1	P38398-1.2	E1735G	Pathogenic	0.735
BRCA1	P38398-1.2	E1735H	Neutral	0.296
BRCA1	P38398-1.2	E1735I	Pathogenic	0.581
BRCA1	P38398-1.2	E1735K	Neutral	0.301
BRCA1	P38398-1.2	E1735L	Pathogenic	0.582
BRCA1	P38398-1.2	E1735M	Neutral	0.494
BRCA1	P38398-1.2	E1735N	Neutral	0.318
BRCA1	P38398-1.2	E1735P	Neutral	0.428
BRCA1	P38398-1.2	E1735Q	Neutral	0.158
BRCA1	P38398-1.2	E1735R	Neutral	0.452
BRCA1	P38398-1.2	E1735S	Neutral	0.435
BRCA1	P38398-1.2	E1735T	Neutral	0.414
BRCA1	P38398-1.2	E1735V	Neutral	0.433
BRCA1	P38398-1.2	E1735W	Pathogenic	0.766
BRCA1	P38398-1.2	E1735Y	Pathogenic	0.588
BRCA1	P38398-1.2	V1736A	Pathogenic	0.537
BRCA1	P38398-1.2	V1736C	Pathogenic	0.526
BRCA1	P38398-1.2	V1736D	Pathogenic	0.665
BRCA1	P38398-1.2	V1736E	Pathogenic	0.526
BRCA1	P38398-1.2	V1736F	Pathogenic	0.585
BRCA1	P38398-1.2	V1736G	Pathogenic	0.84
BRCA1	P38398-1.2	V1736H	Pathogenic	0.664
BRCA1	P38398-1.2	V1736I	Neutral	0.205
BRCA1	P38398-1.2	V1736K	Pathogenic	0.663
BRCA1	P38398-1.2	V1736L	Neutral	0.348
BRCA1	P38398-1.2	V1736M	Neutral	0.35
BRCA1	P38398-1.2	V1736N	Pathogenic	0.641
BRCA1	P38398-1.2	V1736P	Pathogenic	0.593
BRCA1	P38398-1.2	V1736Q	Pathogenic	0.556
BRCA1	P38398-1.2	V1736R	Pathogenic	0.79
BRCA1	P38398-1.2	V1736S	Pathogenic	0.676
BRCA1	P38398-1.2	V1736T	Neutral	0.394
BRCA1	P38398-1.2	V1736W	Pathogenic	0.843
BRCA1	P38398-1.2	V1736Y	Pathogenic	0.618
BRCA1	P38398-1.2	R1737A	Pathogenic	0.625
BRCA1	P38398-1.2	R1737C	Pathogenic	0.69
BRCA1	P38398-1.2	R1737D	Pathogenic	0.589
BRCA1	P38398-1.2	R1737E	Neutral	0.317
BRCA1	P38398-1.2	R1737F	Neutral	0.425
BRCA1	P38398-1.2	R1737G	Pathogenic	0.786
BRCA1	P38398-1.2	R1737H	Neutral	0.272
BRCA1	P38398-1.2	R1737I	Neutral	0.486
BRCA1	P38398-1.2	R1737K	Neutral	0.112
BRCA1	P38398-1.2	R1737L	Neutral	0.397
BRCA1	P38398-1.2	R1737M	Neutral	0.315
BRCA1	P38398-1.2	R1737N	Neutral	0.382
BRCA1	P38398-1.2	R1737P	Pathogenic	0.588
BRCA1	P38398-1.2	R1737Q	Neutral	0.222
BRCA1	P38398-1.2	R1737S	Pathogenic	0.594
BRCA1	P38398-1.2	R1737T	Neutral	0.483
BRCA1	P38398-1.2	R1737V	Pathogenic	0.593
BRCA1	P38398-1.2	R1737W	Neutral	0.434
BRCA1	P38398-1.2	R1737Y	Neutral	0.314
BRCA1	P38398-1.2	G1738A	Pathogenic	0.537
BRCA1	P38398-1.2	G1738C	Pathogenic	0.839
BRCA1	P38398-1.2	G1738D	Pathogenic	0.738
BRCA1	P38398-1.2	G1738E	Pathogenic	0.859
BRCA1	P38398-1.2	G1738F	Pathogenic	0.938
BRCA1	P38398-1.2	G1738H	Pathogenic	0.882
BRCA1	P38398-1.2	G1738I	Pathogenic	0.945
BRCA1	P38398-1.2	G1738K	Pathogenic	0.915
BRCA1	P38398-1.2	G1738L	Pathogenic	0.945
BRCA1	P38398-1.2	G1738M	Pathogenic	0.923
BRCA1	P38398-1.2	G1738N	Pathogenic	0.687
BRCA1	P38398-1.2	G1738P	Pathogenic	0.799
BRCA1	P38398-1.2	G1738Q	Pathogenic	0.872
BRCA1	P38398-1.2	G1738R	Pathogenic	0.935
BRCA1	P38398-1.2	G1738S	Pathogenic	0.571
BRCA1	P38398-1.2	G1738T	Pathogenic	0.811
BRCA1	P38398-1.2	G1738V	Pathogenic	0.888
BRCA1	P38398-1.2	G1738W	Pathogenic	0.951
BRCA1	P38398-1.2	G1738Y	Pathogenic	0.946
BRCA1	P38398-1.2	D1739A	Pathogenic	0.654
BRCA1	P38398-1.2	D1739C	Pathogenic	0.638
BRCA1	P38398-1.2	D1739E	Neutral	0.282
BRCA1	P38398-1.2	D1739F	Pathogenic	0.805
BRCA1	P38398-1.2	D1739G	Pathogenic	0.669
BRCA1	P38398-1.2	D1739H	Pathogenic	0.585
BRCA1	P38398-1.2	D1739I	Pathogenic	0.764
BRCA1	P38398-1.2	D1739K	Pathogenic	0.676
BRCA1	P38398-1.2	D1739L	Pathogenic	0.823
BRCA1	P38398-1.2	D1739M	Pathogenic	0.766
BRCA1	P38398-1.2	D1739N	Neutral	0.298
BRCA1	P38398-1.2	D1739P	Neutral	0.439
BRCA1	P38398-1.2	D1739Q	Neutral	0.474
BRCA1	P38398-1.2	D1739R	Pathogenic	0.8
BRCA1	P38398-1.2	D1739S	Neutral	0.446
BRCA1	P38398-1.2	D1739T	Neutral	0.447
BRCA1	P38398-1.2	D1739V	Pathogenic	0.682
BRCA1	P38398-1.2	D1739W	Pathogenic	0.916
BRCA1	P38398-1.2	D1739Y	Pathogenic	0.827
BRCA1	P38398-1.2	V1740A	Pathogenic	0.544
BRCA1	P38398-1.2	V1740C	Pathogenic	0.532
BRCA1	P38398-1.2	V1740D	Pathogenic	0.671
BRCA1	P38398-1.2	V1740E	Pathogenic	0.532
BRCA1	P38398-1.2	V1740F	Pathogenic	0.591
BRCA1	P38398-1.2	V1740G	Pathogenic	0.843
BRCA1	P38398-1.2	V1740H	Pathogenic	0.67
BRCA1	P38398-1.2	V1740I	Neutral	0.209
BRCA1	P38398-1.2	V1740K	Pathogenic	0.668
BRCA1	P38398-1.2	V1740L	Neutral	0.354
BRCA1	P38398-1.2	V1740M	Neutral	0.356
BRCA1	P38398-1.2	V1740N	Pathogenic	0.647
BRCA1	P38398-1.2	V1740P	Pathogenic	0.599
BRCA1	P38398-1.2	V1740Q	Pathogenic	0.562
BRCA1	P38398-1.2	V1740R	Pathogenic	0.795
BRCA1	P38398-1.2	V1740S	Pathogenic	0.682
BRCA1	P38398-1.2	V1740T	Neutral	0.4
BRCA1	P38398-1.2	V1740W	Pathogenic	0.847
BRCA1	P38398-1.2	V1740Y	Pathogenic	0.624
BRCA1	P38398-1.2	V1741A	Neutral	0.096
BRCA1	P38398-1.2	V1741C	Neutral	0.092
BRCA1	P38398-1.2	V1741D	Neutral	0.154
BRCA1	P38398-1.2	V1741E	Neutral	0.092
BRCA1	P38398-1.2	V1741F	Neutral	0.114
BRCA1	P38398-1.2	V1741G	Neutral	0.324
BRCA1	P38398-1.2	V1741H	Neutral	0.153
BRCA1	P38398-1.2	V1741I	Neutral	0.023
BRCA1	P38398-1.2	V1741K	Neutral	0.152
BRCA1	P38398-1.2	V1741L	Neutral	0.046
BRCA1	P38398-1.2	V1741M	Neutral	0.047
BRCA1	P38398-1.2	V1741N	Neutral	0.14
BRCA1	P38398-1.2	V1741P	Neutral	0.117
BRCA1	P38398-1.2	V1741Q	Neutral	0.102
BRCA1	P38398-1.2	V1741R	Neutral	0.256
BRCA1	P38398-1.2	V1741S	Neutral	0.16
BRCA1	P38398-1.2	V1741T	Neutral	0.056
BRCA1	P38398-1.2	V1741W	Neutral	0.33
BRCA1	P38398-1.2	V1741Y	Neutral	0.129
BRCA1	P38398-1.2	N1742A	Neutral	0.374
BRCA1	P38398-1.2	N1742C	Neutral	0.357
BRCA1	P38398-1.2	N1742D	Neutral	0.106
BRCA1	P38398-1.2	N1742E	Neutral	0.17
BRCA1	P38398-1.2	N1742F	Pathogenic	0.51
BRCA1	P38398-1.2	N1742G	Neutral	0.306
BRCA1	P38398-1.2	N1742H	Neutral	0.147
BRCA1	P38398-1.2	N1742I	Neutral	0.449
BRCA1	P38398-1.2	N1742K	Neutral	0.266
BRCA1	P38398-1.2	N1742L	Neutral	0.45
BRCA1	P38398-1.2	N1742M	Neutral	0.364
BRCA1	P38398-1.2	N1742P	Neutral	0.262
BRCA1	P38398-1.2	N1742Q	Neutral	0.186
BRCA1	P38398-1.2	N1742R	Neutral	0.326
BRCA1	P38398-1.2	N1742S	Neutral	0.15
BRCA1	P38398-1.2	N1742T	Neutral	0.139
BRCA1	P38398-1.2	N1742V	Neutral	0.351
BRCA1	P38398-1.2	N1742W	Pathogenic	0.735
BRCA1	P38398-1.2	N1742Y	Neutral	0.457
BRCA1	P38398-1.2	G1743A	Pathogenic	0.611
BRCA1	P38398-1.2	G1743C	Pathogenic	0.876
BRCA1	P38398-1.2	G1743D	Pathogenic	0.792
BRCA1	P38398-1.2	G1743E	Pathogenic	0.891
BRCA1	P38398-1.2	G1743F	Pathogenic	0.954
BRCA1	P38398-1.2	G1743H	Pathogenic	0.91
BRCA1	P38398-1.2	G1743I	Pathogenic	0.959
BRCA1	P38398-1.2	G1743K	Pathogenic	0.936
BRCA1	P38398-1.2	G1743L	Pathogenic	0.959
BRCA1	P38398-1.2	G1743M	Pathogenic	0.942
BRCA1	P38398-1.2	G1743N	Pathogenic	0.748
BRCA1	P38398-1.2	G1743P	Pathogenic	0.843
BRCA1	P38398-1.2	G1743Q	Pathogenic	0.902
BRCA1	P38398-1.2	G1743R	Pathogenic	0.951
BRCA1	P38398-1.2	G1743S	Pathogenic	0.643
BRCA1	P38398-1.2	G1743T	Pathogenic	0.853
BRCA1	P38398-1.2	G1743V	Pathogenic	0.914
BRCA1	P38398-1.2	G1743W	Pathogenic	0.964
BRCA1	P38398-1.2	G1743Y	Pathogenic	0.96
BRCA1	P38398-1.2	R1744A	Pathogenic	0.86
BRCA1	P38398-1.2	R1744C	Pathogenic	0.892
BRCA1	P38398-1.2	R1744D	Pathogenic	0.842
BRCA1	P38398-1.2	R1744E	Pathogenic	0.632
BRCA1	P38398-1.2	R1744F	Pathogenic	0.733
BRCA1	P38398-1.2	R1744G	Pathogenic	0.932
BRCA1	P38398-1.2	R1744H	Pathogenic	0.581
BRCA1	P38398-1.2	R1744I	Pathogenic	0.778
BRCA1	P38398-1.2	R1744K	Neutral	0.319
BRCA1	P38398-1.2	R1744L	Pathogenic	0.709
BRCA1	P38398-1.2	R1744M	Pathogenic	0.631
BRCA1	P38398-1.2	R1744N	Pathogenic	0.696
BRCA1	P38398-1.2	R1744P	Pathogenic	0.841
BRCA1	P38398-1.2	R1744Q	Pathogenic	0.514
BRCA1	P38398-1.2	R1744S	Pathogenic	0.845
BRCA1	P38398-1.2	R1744T	Pathogenic	0.776
BRCA1	P38398-1.2	R1744V	Pathogenic	0.844
BRCA1	P38398-1.2	R1744W	Pathogenic	0.74
BRCA1	P38398-1.2	R1744Y	Pathogenic	0.629
BRCA1	P38398-1.2	N1745A	Neutral	0.317
BRCA1	P38398-1.2	N1745C	Neutral	0.302
BRCA1	P38398-1.2	N1745D	Neutral	0.085
BRCA1	P38398-1.2	N1745E	Neutral	0.138
BRCA1	P38398-1.2	N1745F	Neutral	0.448
BRCA1	P38398-1.2	N1745G	Neutral	0.256
BRCA1	P38398-1.2	N1745H	Neutral	0.118
BRCA1	P38398-1.2	N1745I	Neutral	0.389
BRCA1	P38398-1.2	N1745K	Neutral	0.221
BRCA1	P38398-1.2	N1745L	Neutral	0.389
BRCA1	P38398-1.2	N1745M	Neutral	0.309
BRCA1	P38398-1.2	N1745P	Neutral	0.217
BRCA1	P38398-1.2	N1745Q	Neutral	0.151
BRCA1	P38398-1.2	N1745R	Neutral	0.274
BRCA1	P38398-1.2	N1745S	Neutral	0.121
BRCA1	P38398-1.2	N1745T	Neutral	0.112
BRCA1	P38398-1.2	N1745V	Neutral	0.297
BRCA1	P38398-1.2	N1745W	Pathogenic	0.683
BRCA1	P38398-1.2	N1745Y	Neutral	0.396
BRCA1	P38398-1.2	H1746A	Pathogenic	0.904
BRCA1	P38398-1.2	H1746C	Pathogenic	0.898
BRCA1	P38398-1.2	H1746D	Pathogenic	0.791
BRCA1	P38398-1.2	H1746E	Pathogenic	0.639
BRCA1	P38398-1.2	H1746F	Pathogenic	0.749
BRCA1	P38398-1.2	H1746G	Pathogenic	0.935
BRCA1	P38398-1.2	H1746I	Pathogenic	0.829
BRCA1	P38398-1.2	H1746K	Pathogenic	0.751
BRCA1	P38398-1.2	H1746L	Pathogenic	0.829
BRCA1	P38398-1.2	H1746M	Pathogenic	0.773
BRCA1	P38398-1.2	H1746N	Pathogenic	0.622
BRCA1	P38398-1.2	H1746P	Pathogenic	0.849
BRCA1	P38398-1.2	H1746Q	Pathogenic	0.615
BRCA1	P38398-1.2	H1746R	Pathogenic	0.737
BRCA1	P38398-1.2	H1746S	Pathogenic	0.851
BRCA1	P38398-1.2	H1746T	Pathogenic	0.841
BRCA1	P38398-1.2	H1746V	Pathogenic	0.851
BRCA1	P38398-1.2	H1746W	Pathogenic	0.888
BRCA1	P38398-1.2	H1746Y	Pathogenic	0.538
BRCA1	P38398-1.2	Q1747A	Neutral	0.321
BRCA1	P38398-1.2	Q1747C	Neutral	0.388
BRCA1	P38398-1.2	Q1747D	Neutral	0.162
BRCA1	P38398-1.2	Q1747E	Neutral	0.059
BRCA1	P38398-1.2	Q1747F	Neutral	0.348
BRCA1	P38398-1.2	Q1747G	Pathogenic	0.511
BRCA1	P38398-1.2	Q1747H	Neutral	0.113
BRCA1	P38398-1.2	Q1747I	Neutral	0.295
BRCA1	P38398-1.2	Q1747K	Neutral	0.113
BRCA1	P38398-1.2	Q1747L	Neutral	0.225
BRCA1	P38398-1.2	Q1747M	Neutral	0.124
BRCA1	P38398-1.2	Q1747N	Neutral	0.147
BRCA1	P38398-1.2	Q1747P	Neutral	0.22
BRCA1	P38398-1.2	Q1747R	Neutral	0.145
BRCA1	P38398-1.2	Q1747S	Neutral	0.224
BRCA1	P38398-1.2	Q1747T	Neutral	0.21
BRCA1	P38398-1.2	Q1747V	Neutral	0.223
BRCA1	P38398-1.2	Q1747W	Neutral	0.407
BRCA1	P38398-1.2	Q1747Y	Neutral	0.23
BRCA1	P38398-1.2	G1748A	Neutral	0.37
BRCA1	P38398-1.2	G1748C	Pathogenic	0.725
BRCA1	P38398-1.2	G1748D	Pathogenic	0.588
BRCA1	P38398-1.2	G1748E	Pathogenic	0.754
BRCA1	P38398-1.2	G1748F	Pathogenic	0.885
BRCA1	P38398-1.2	G1748H	Pathogenic	0.791
BRCA1	P38398-1.2	G1748I	Pathogenic	0.897
BRCA1	P38398-1.2	G1748K	Pathogenic	0.844
BRCA1	P38398-1.2	G1748L	Pathogenic	0.897
BRCA1	P38398-1.2	G1748M	Pathogenic	0.859
BRCA1	P38398-1.2	G1748N	Pathogenic	0.526
BRCA1	P38398-1.2	G1748P	Pathogenic	0.668
BRCA1	P38398-1.2	G1748Q	Pathogenic	0.776
BRCA1	P38398-1.2	G1748R	Pathogenic	0.879
BRCA1	P38398-1.2	G1748S	Neutral	0.403
BRCA1	P38398-1.2	G1748T	Pathogenic	0.684
BRCA1	P38398-1.2	G1748V	Pathogenic	0.8
BRCA1	P38398-1.2	G1748W	Pathogenic	0.908
BRCA1	P38398-1.2	G1748Y	Pathogenic	0.899
BRCA1	P38398-1.2	P1749A	Pathogenic	0.699
BRCA1	P38398-1.2	P1749C	Pathogenic	0.76
BRCA1	P38398-1.2	P1749D	Pathogenic	0.583
BRCA1	P38398-1.2	P1749E	Pathogenic	0.676
BRCA1	P38398-1.2	P1749F	Pathogenic	0.918
BRCA1	P38398-1.2	P1749G	Pathogenic	0.835
BRCA1	P38398-1.2	P1749H	Pathogenic	0.788
BRCA1	P38398-1.2	P1749I	Pathogenic	0.858
BRCA1	P38398-1.2	P1749K	Pathogenic	0.787
BRCA1	P38398-1.2	P1749L	Pathogenic	0.859
BRCA1	P38398-1.2	P1749M	Pathogenic	0.81
BRCA1	P38398-1.2	P1749N	Pathogenic	0.692
BRCA1	P38398-1.2	P1749Q	Pathogenic	0.702
BRCA1	P38398-1.2	P1749R	Pathogenic	0.876
BRCA1	P38398-1.2	P1749S	Pathogenic	0.669
BRCA1	P38398-1.2	P1749T	Pathogenic	0.598
BRCA1	P38398-1.2	P1749V	Pathogenic	0.736
BRCA1	P38398-1.2	P1749W	Pathogenic	0.954
BRCA1	P38398-1.2	P1749Y	Pathogenic	0.9
BRCA1	P38398-1.2	K1750A	Neutral	0.156
BRCA1	P38398-1.2	K1750C	Neutral	0.198
BRCA1	P38398-1.2	K1750D	Neutral	0.099
BRCA1	P38398-1.2	K1750E	Neutral	0.034
BRCA1	P38398-1.2	K1750F	Neutral	0.076
BRCA1	P38398-1.2	K1750G	Neutral	0.289
BRCA1	P38398-1.2	K1750H	Neutral	0.056
BRCA1	P38398-1.2	K1750I	Neutral	0.095
BRCA1	P38398-1.2	K1750L	Neutral	0.068
BRCA1	P38398-1.2	K1750M	Neutral	0.049
BRCA1	P38398-1.2	K1750N	Neutral	0.064
BRCA1	P38398-1.2	K1750P	Neutral	0.099
BRCA1	P38398-1.2	K1750Q	Neutral	0.031
BRCA1	P38398-1.2	K1750R	Neutral	0.018
BRCA1	P38398-1.2	K1750S	Neutral	0.101
BRCA1	P38398-1.2	K1750T	Neutral	0.094
BRCA1	P38398-1.2	K1750V	Neutral	0.101
BRCA1	P38398-1.2	K1750W	Neutral	0.131
BRCA1	P38398-1.2	K1750Y	Neutral	0.062
BRCA1	P38398-1.2	R1751A	Pathogenic	0.826
BRCA1	P38398-1.2	R1751C	Pathogenic	0.864
BRCA1	P38398-1.2	R1751D	Pathogenic	0.804
BRCA1	P38398-1.2	R1751E	Pathogenic	0.569
BRCA1	P38398-1.2	R1751F	Pathogenic	0.678
BRCA1	P38398-1.2	R1751G	Pathogenic	0.913
BRCA1	P38398-1.2	R1751H	Pathogenic	0.516
BRCA1	P38398-1.2	R1751I	Pathogenic	0.729
BRCA1	P38398-1.2	R1751K	Neutral	0.265
BRCA1	P38398-1.2	R1751L	Pathogenic	0.652
BRCA1	P38398-1.2	R1751M	Pathogenic	0.568
BRCA1	P38398-1.2	R1751N	Pathogenic	0.638
BRCA1	P38398-1.2	R1751P	Pathogenic	0.803
BRCA1	P38398-1.2	R1751Q	Neutral	0.449
BRCA1	P38398-1.2	R1751S	Pathogenic	0.807
BRCA1	P38398-1.2	R1751T	Pathogenic	0.727
BRCA1	P38398-1.2	R1751V	Pathogenic	0.806
BRCA1	P38398-1.2	R1751W	Pathogenic	0.686
BRCA1	P38398-1.2	R1751Y	Pathogenic	0.566
BRCA1	P38398-1.2	A1752C	Neutral	0.19
BRCA1	P38398-1.2	A1752D	Neutral	0.351
BRCA1	P38398-1.2	A1752E	Neutral	0.359
BRCA1	P38398-1.2	A1752F	Pathogenic	0.587
BRCA1	P38398-1.2	A1752G	Neutral	0.191
BRCA1	P38398-1.2	A1752H	Pathogenic	0.5
BRCA1	P38398-1.2	A1752I	Neutral	0.437
BRCA1	P38398-1.2	A1752K	Neutral	0.498
BRCA1	P38398-1.2	A1752L	Neutral	0.437
BRCA1	P38398-1.2	A1752M	Neutral	0.439
BRCA1	P38398-1.2	A1752N	Neutral	0.377
BRCA1	P38398-1.2	A1752P	Neutral	0.271
BRCA1	P38398-1.2	A1752Q	Neutral	0.387
BRCA1	P38398-1.2	A1752R	Pathogenic	0.57
BRCA1	P38398-1.2	A1752S	Neutral	0.11
BRCA1	P38398-1.2	A1752T	Neutral	0.218
BRCA1	P38398-1.2	A1752V	Neutral	0.263
BRCA1	P38398-1.2	A1752W	Pathogenic	0.791
BRCA1	P38398-1.2	A1752Y	Pathogenic	0.623
BRCA1	P38398-1.2	R1753A	Pathogenic	0.824
BRCA1	P38398-1.2	R1753C	Pathogenic	0.863
BRCA1	P38398-1.2	R1753D	Pathogenic	0.802
BRCA1	P38398-1.2	R1753E	Pathogenic	0.566
BRCA1	P38398-1.2	R1753F	Pathogenic	0.676
BRCA1	P38398-1.2	R1753G	Pathogenic	0.912
BRCA1	P38398-1.2	R1753H	Pathogenic	0.513
BRCA1	P38398-1.2	R1753I	Pathogenic	0.727
BRCA1	P38398-1.2	R1753K	Neutral	0.263
BRCA1	P38398-1.2	R1753L	Pathogenic	0.65
BRCA1	P38398-1.2	R1753M	Pathogenic	0.565
BRCA1	P38398-1.2	R1753N	Pathogenic	0.635
BRCA1	P38398-1.2	R1753P	Pathogenic	0.801
BRCA1	P38398-1.2	R1753Q	Neutral	0.446
BRCA1	P38398-1.2	R1753S	Pathogenic	0.805
BRCA1	P38398-1.2	R1753T	Pathogenic	0.725
BRCA1	P38398-1.2	R1753V	Pathogenic	0.804
BRCA1	P38398-1.2	R1753W	Pathogenic	0.684
BRCA1	P38398-1.2	R1753Y	Pathogenic	0.563
BRCA1	P38398-1.2	E1754A	Pathogenic	0.557
BRCA1	P38398-1.2	E1754C	Pathogenic	0.708
BRCA1	P38398-1.2	E1754D	Neutral	0.201
BRCA1	P38398-1.2	E1754F	Pathogenic	0.639
BRCA1	P38398-1.2	E1754G	Pathogenic	0.735
BRCA1	P38398-1.2	E1754H	Neutral	0.296
BRCA1	P38398-1.2	E1754I	Pathogenic	0.581
BRCA1	P38398-1.2	E1754K	Neutral	0.301
BRCA1	P38398-1.2	E1754L	Pathogenic	0.582
BRCA1	P38398-1.2	E1754M	Neutral	0.494
BRCA1	P38398-1.2	E1754N	Neutral	0.318
BRCA1	P38398-1.2	E1754P	Neutral	0.428
BRCA1	P38398-1.2	E1754Q	Neutral	0.158
BRCA1	P38398-1.2	E1754R	Neutral	0.452
BRCA1	P38398-1.2	E1754S	Neutral	0.435
BRCA1	P38398-1.2	E1754T	Neutral	0.414
BRCA1	P38398-1.2	E1754V	Neutral	0.433
BRCA1	P38398-1.2	E1754W	Pathogenic	0.766
BRCA1	P38398-1.2	E1754Y	Pathogenic	0.588
BRCA1	P38398-1.2	S1755A	Neutral	0.302
BRCA1	P38398-1.2	S1755C	Pathogenic	0.509
BRCA1	P38398-1.2	S1755D	Neutral	0.447
BRCA1	P38398-1.2	S1755E	Pathogenic	0.547
BRCA1	P38398-1.2	S1755F	Pathogenic	0.813
BRCA1	P38398-1.2	S1755G	Neutral	0.489
BRCA1	P38398-1.2	S1755H	Pathogenic	0.682
BRCA1	P38398-1.2	S1755I	Pathogenic	0.773
BRCA1	P38398-1.2	S1755K	Pathogenic	0.681
BRCA1	P38398-1.2	S1755L	Pathogenic	0.774
BRCA1	P38398-1.2	S1755M	Pathogenic	0.706
BRCA1	P38398-1.2	S1755N	Neutral	0.386
BRCA1	P38398-1.2	S1755P	Pathogenic	0.532
BRCA1	P38398-1.2	S1755Q	Pathogenic	0.577
BRCA1	P38398-1.2	S1755R	Pathogenic	0.804
BRCA1	P38398-1.2	S1755T	Neutral	0.372
BRCA1	P38398-1.2	S1755V	Pathogenic	0.693
BRCA1	P38398-1.2	S1755W	Pathogenic	0.92
BRCA1	P38398-1.2	S1755Y	Pathogenic	0.835
BRCA1	P38398-1.2	Q1756A	Neutral	0.064
BRCA1	P38398-1.2	Q1756C	Neutral	0.083
BRCA1	P38398-1.2	Q1756D	Neutral	0.027
BRCA1	P38398-1.2	Q1756E	Neutral	0.009
BRCA1	P38398-1.2	Q1756F	Neutral	0.071
BRCA1	P38398-1.2	Q1756G	Neutral	0.13
BRCA1	P38398-1.2	Q1756H	Neutral	0.018
BRCA1	P38398-1.2	Q1756I	Neutral	0.057
BRCA1	P38398-1.2	Q1756K	Neutral	0.018
BRCA1	P38398-1.2	Q1756L	Neutral	0.04
BRCA1	P38398-1.2	Q1756M	Neutral	0.02
BRCA1	P38398-1.2	Q1756N	Neutral	0.024
BRCA1	P38398-1.2	Q1756P	Neutral	0.039
BRCA1	P38398-1.2	Q1756R	Neutral	0.024
BRCA1	P38398-1.2	Q1756S	Neutral	0.04
BRCA1	P38398-1.2	Q1756T	Neutral	0.037
BRCA1	P38398-1.2	Q1756V	Neutral	0.04
BRCA1	P38398-1.2	Q1756W	Neutral	0.09
BRCA1	P38398-1.2	Q1756Y	Neutral	0.041
BRCA1	P38398-1.2	D1757A	Neutral	0.092
BRCA1	P38398-1.2	D1757C	Neutral	0.087
BRCA1	P38398-1.2	D1757E	Neutral	0.021
BRCA1	P38398-1.2	D1757F	Neutral	0.182
BRCA1	P38398-1.2	D1757G	Neutral	0.098
BRCA1	P38398-1.2	D1757H	Neutral	0.071
BRCA1	P38398-1.2	D1757I	Neutral	0.148
BRCA1	P38398-1.2	D1757K	Neutral	0.101
BRCA1	P38398-1.2	D1757L	Neutral	0.2
BRCA1	P38398-1.2	D1757M	Neutral	0.15
BRCA1	P38398-1.2	D1757N	Neutral	0.022
BRCA1	P38398-1.2	D1757P	Neutral	0.04
BRCA1	P38398-1.2	D1757Q	Neutral	0.046
BRCA1	P38398-1.2	D1757R	Neutral	0.177
BRCA1	P38398-1.2	D1757S	Neutral	0.042
BRCA1	P38398-1.2	D1757T	Neutral	0.042
BRCA1	P38398-1.2	D1757V	Neutral	0.103
BRCA1	P38398-1.2	D1757W	Neutral	0.371
BRCA1	P38398-1.2	D1757Y	Neutral	0.205
BRCA1	P38398-1.2	R1758A	Neutral	0.229
BRCA1	P38398-1.2	R1758C	Neutral	0.285
BRCA1	P38398-1.2	R1758D	Neutral	0.204
BRCA1	P38398-1.2	R1758E	Neutral	0.076
BRCA1	P38398-1.2	R1758F	Neutral	0.116
BRCA1	P38398-1.2	R1758G	Neutral	0.396
BRCA1	P38398-1.2	R1758H	Neutral	0.062
BRCA1	P38398-1.2	R1758I	Neutral	0.144
BRCA1	P38398-1.2	R1758K	Neutral	0.022
BRCA1	P38398-1.2	R1758L	Neutral	0.105
BRCA1	P38398-1.2	R1758M	Neutral	0.076
BRCA1	P38398-1.2	R1758N	Neutral	0.099
BRCA1	P38398-1.2	R1758P	Neutral	0.203
BRCA1	P38398-1.2	R1758Q	Neutral	0.048
BRCA1	P38398-1.2	R1758S	Neutral	0.207
BRCA1	P38398-1.2	R1758T	Neutral	0.143
BRCA1	P38398-1.2	R1758V	Neutral	0.206
BRCA1	P38398-1.2	R1758W	Neutral	0.12
BRCA1	P38398-1.2	R1758Y	Neutral	0.075
BRCA1	P38398-1.2	K1759A	Neutral	0.44
BRCA1	P38398-1.2	K1759C	Pathogenic	0.513
BRCA1	P38398-1.2	K1759D	Neutral	0.32
BRCA1	P38398-1.2	K1759E	Neutral	0.132
BRCA1	P38398-1.2	K1759F	Neutral	0.259
BRCA1	P38398-1.2	K1759G	Pathogenic	0.634
BRCA1	P38398-1.2	K1759H	Neutral	0.202
BRCA1	P38398-1.2	K1759I	Neutral	0.308
BRCA1	P38398-1.2	K1759L	Neutral	0.237
BRCA1	P38398-1.2	K1759M	Neutral	0.178
BRCA1	P38398-1.2	K1759N	Neutral	0.226
BRCA1	P38398-1.2	K1759P	Neutral	0.318
BRCA1	P38398-1.2	K1759Q	Neutral	0.119
BRCA1	P38398-1.2	K1759R	Neutral	0.074
BRCA1	P38398-1.2	K1759S	Neutral	0.324
BRCA1	P38398-1.2	K1759T	Neutral	0.306
BRCA1	P38398-1.2	K1759V	Neutral	0.323
BRCA1	P38398-1.2	K1759W	Neutral	0.392
BRCA1	P38398-1.2	K1759Y	Neutral	0.22
BRCA1	P38398-1.2	I1760A	Pathogenic	0.61
BRCA1	P38398-1.2	I1760C	Pathogenic	0.509
BRCA1	P38398-1.2	I1760D	Pathogenic	0.65
BRCA1	P38398-1.2	I1760E	Pathogenic	0.556
BRCA1	P38398-1.2	I1760F	Neutral	0.287
BRCA1	P38398-1.2	I1760G	Pathogenic	0.876
BRCA1	P38398-1.2	I1760H	Pathogenic	0.51
BRCA1	P38398-1.2	I1760K	Pathogenic	0.532
BRCA1	P38398-1.2	I1760L	Neutral	0.132
BRCA1	P38398-1.2	I1760M	Neutral	0.178
BRCA1	P38398-1.2	I1760N	Pathogenic	0.626
BRCA1	P38398-1.2	I1760P	Pathogenic	0.662
BRCA1	P38398-1.2	I1760Q	Pathogenic	0.53
BRCA1	P38398-1.2	I1760R	Pathogenic	0.603
BRCA1	P38398-1.2	I1760S	Pathogenic	0.662
BRCA1	P38398-1.2	I1760T	Neutral	0.467
BRCA1	P38398-1.2	I1760V	Neutral	0.138
BRCA1	P38398-1.2	I1760W	Pathogenic	0.689
BRCA1	P38398-1.2	I1760Y	Neutral	0.394
BRCA1	P38398-1.2	F1761A	Pathogenic	0.911
BRCA1	P38398-1.2	F1761C	Pathogenic	0.871
BRCA1	P38398-1.2	F1761D	Pathogenic	0.894
BRCA1	P38398-1.2	F1761E	Pathogenic	0.85
BRCA1	P38398-1.2	F1761G	Pathogenic	0.957
BRCA1	P38398-1.2	F1761H	Pathogenic	0.695
BRCA1	P38398-1.2	F1761I	Pathogenic	0.588
BRCA1	P38398-1.2	F1761K	Pathogenic	0.76
BRCA1	P38398-1.2	F1761L	Pathogenic	0.588
BRCA1	P38398-1.2	F1761M	Pathogenic	0.586
BRCA1	P38398-1.2	F1761N	Pathogenic	0.883
BRCA1	P38398-1.2	F1761P	Pathogenic	0.927
BRCA1	P38398-1.2	F1761Q	Pathogenic	0.836
BRCA1	P38398-1.2	F1761R	Pathogenic	0.808
BRCA1	P38398-1.2	F1761S	Pathogenic	0.899
BRCA1	P38398-1.2	F1761T	Pathogenic	0.851
BRCA1	P38398-1.2	F1761V	Pathogenic	0.756
BRCA1	P38398-1.2	F1761W	Pathogenic	0.589
BRCA1	P38398-1.2	F1761Y	Neutral	0.297
BRCA1	P38398-1.2	R1762A	Neutral	0.071
BRCA1	P38398-1.2	R1762C	Neutral	0.093
BRCA1	P38398-1.2	R1762D	Neutral	0.062
BRCA1	P38398-1.2	R1762E	Neutral	0.021
BRCA1	P38398-1.2	R1762F	Neutral	0.033
BRCA1	P38398-1.2	R1762G	Neutral	0.144
BRCA1	P38398-1.2	R1762H	Neutral	0.017
BRCA1	P38398-1.2	R1762I	Neutral	0.042
BRCA1	P38398-1.2	R1762K	Neutral	0.006
BRCA1	P38398-1.2	R1762L	Neutral	0.029
BRCA1	P38398-1.2	R1762M	Neutral	0.021
BRCA1	P38398-1.2	R1762N	Neutral	0.028
BRCA1	P38398-1.2	R1762P	Neutral	0.061
BRCA1	P38398-1.2	R1762Q	Neutral	0.013
BRCA1	P38398-1.2	R1762S	Neutral	0.063
BRCA1	P38398-1.2	R1762T	Neutral	0.041
BRCA1	P38398-1.2	R1762V	Neutral	0.063
BRCA1	P38398-1.2	R1762W	Neutral	0.034
BRCA1	P38398-1.2	R1762Y	Neutral	0.021
BRCA1	P38398-1.2	G1763A	Neutral	0.45
BRCA1	P38398-1.2	G1763C	Pathogenic	0.786
BRCA1	P38398-1.2	G1763D	Pathogenic	0.665
BRCA1	P38398-1.2	G1763E	Pathogenic	0.81
BRCA1	P38398-1.2	G1763F	Pathogenic	0.915
BRCA1	P38398-1.2	G1763H	Pathogenic	0.841
BRCA1	P38398-1.2	G1763I	Pathogenic	0.924
BRCA1	P38398-1.2	G1763K	Pathogenic	0.883
BRCA1	P38398-1.2	G1763L	Pathogenic	0.924
BRCA1	P38398-1.2	G1763M	Pathogenic	0.895
BRCA1	P38398-1.2	G1763N	Pathogenic	0.607
BRCA1	P38398-1.2	G1763P	Pathogenic	0.737
BRCA1	P38398-1.2	G1763Q	Pathogenic	0.828
BRCA1	P38398-1.2	G1763R	Pathogenic	0.91
BRCA1	P38398-1.2	G1763S	Neutral	0.484
BRCA1	P38398-1.2	G1763T	Pathogenic	0.751
BRCA1	P38398-1.2	G1763V	Pathogenic	0.848
BRCA1	P38398-1.2	G1763W	Pathogenic	0.932
BRCA1	P38398-1.2	G1763Y	Pathogenic	0.926
BRCA1	P38398-1.2	L1764A	Pathogenic	0.732
BRCA1	P38398-1.2	L1764C	Pathogenic	0.644
BRCA1	P38398-1.2	L1764D	Pathogenic	0.824
BRCA1	P38398-1.2	L1764E	Pathogenic	0.686
BRCA1	P38398-1.2	L1764F	Neutral	0.411
BRCA1	P38398-1.2	L1764G	Pathogenic	0.925
BRCA1	P38398-1.2	L1764H	Pathogenic	0.644
BRCA1	P38398-1.2	L1764I	Neutral	0.209
BRCA1	P38398-1.2	L1764K	Pathogenic	0.579
BRCA1	P38398-1.2	L1764M	Neutral	0.208
BRCA1	P38398-1.2	L1764N	Pathogenic	0.744
BRCA1	P38398-1.2	L1764P	Pathogenic	0.773
BRCA1	P38398-1.2	L1764Q	Pathogenic	0.577
BRCA1	P38398-1.2	L1764R	Pathogenic	0.648
BRCA1	P38398-1.2	L1764S	Pathogenic	0.773
BRCA1	P38398-1.2	L1764T	Pathogenic	0.604
BRCA1	P38398-1.2	L1764V	Neutral	0.365
BRCA1	P38398-1.2	L1764W	Pathogenic	0.728
BRCA1	P38398-1.2	L1764Y	Pathogenic	0.532
BRCA1	P38398-1.2	E1765A	Neutral	0.045
BRCA1	P38398-1.2	E1765C	Neutral	0.084
BRCA1	P38398-1.2	E1765D	Neutral	0.009
BRCA1	P38398-1.2	E1765F	Neutral	0.063
BRCA1	P38398-1.2	E1765G	Neutral	0.095
BRCA1	P38398-1.2	E1765H	Neutral	0.016
BRCA1	P38398-1.2	E1765I	Neutral	0.05
BRCA1	P38398-1.2	E1765K	Neutral	0.016
BRCA1	P38398-1.2	E1765L	Neutral	0.05
BRCA1	P38398-1.2	E1765M	Neutral	0.035
BRCA1	P38398-1.2	E1765N	Neutral	0.017
BRCA1	P38398-1.2	E1765P	Neutral	0.027
BRCA1	P38398-1.2	E1765Q	Neutral	0.007
BRCA1	P38398-1.2	E1765R	Neutral	0.03
BRCA1	P38398-1.2	E1765S	Neutral	0.028
BRCA1	P38398-1.2	E1765T	Neutral	0.026
BRCA1	P38398-1.2	E1765V	Neutral	0.028
BRCA1	P38398-1.2	E1765W	Neutral	0.11
BRCA1	P38398-1.2	E1765Y	Neutral	0.051
BRCA1	P38398-1.2	I1766A	Neutral	0.303
BRCA1	P38398-1.2	I1766C	Neutral	0.224
BRCA1	P38398-1.2	I1766D	Neutral	0.341
BRCA1	P38398-1.2	I1766E	Neutral	0.258
BRCA1	P38398-1.2	I1766F	Neutral	0.1
BRCA1	P38398-1.2	I1766G	Pathogenic	0.662
BRCA1	P38398-1.2	I1766H	Neutral	0.224
BRCA1	P38398-1.2	I1766K	Neutral	0.24
BRCA1	P38398-1.2	I1766L	Neutral	0.04
BRCA1	P38398-1.2	I1766M	Neutral	0.057
BRCA1	P38398-1.2	I1766N	Neutral	0.317
BRCA1	P38398-1.2	I1766P	Neutral	0.352
BRCA1	P38398-1.2	I1766Q	Neutral	0.239
BRCA1	P38398-1.2	I1766R	Neutral	0.296
BRCA1	P38398-1.2	I1766S	Neutral	0.352
BRCA1	P38398-1.2	I1766T	Neutral	0.196
BRCA1	P38398-1.2	I1766V	Neutral	0.042
BRCA1	P38398-1.2	I1766W	Neutral	0.381
BRCA1	P38398-1.2	I1766Y	Neutral	0.153
BRCA1	P38398-1.2	C1767A	Neutral	0.338
BRCA1	P38398-1.2	C1767D	Pathogenic	0.522
BRCA1	P38398-1.2	C1767E	Pathogenic	0.702
BRCA1	P38398-1.2	C1767F	Pathogenic	0.673
BRCA1	P38398-1.2	C1767G	Pathogenic	0.698
BRCA1	P38398-1.2	C1767H	Pathogenic	0.67
BRCA1	P38398-1.2	C1767I	Pathogenic	0.528
BRCA1	P38398-1.2	C1767K	Pathogenic	0.743
BRCA1	P38398-1.2	C1767L	Pathogenic	0.529
BRCA1	P38398-1.2	C1767M	Pathogenic	0.531
BRCA1	P38398-1.2	C1767N	Pathogenic	0.551
BRCA1	P38398-1.2	C1767P	Pathogenic	0.524
BRCA1	P38398-1.2	C1767Q	Pathogenic	0.648
BRCA1	P38398-1.2	C1767R	Pathogenic	0.794
BRCA1	P38398-1.2	C1767S	Neutral	0.39
BRCA1	P38398-1.2	C1767T	Neutral	0.36
BRCA1	P38398-1.2	C1767V	Neutral	0.426
BRCA1	P38398-1.2	C1767W	Pathogenic	0.792
BRCA1	P38398-1.2	C1767Y	Pathogenic	0.705
BRCA1	P38398-1.2	C1768A	Pathogenic	0.592
BRCA1	P38398-1.2	C1768D	Pathogenic	0.757
BRCA1	P38398-1.2	C1768E	Pathogenic	0.87
BRCA1	P38398-1.2	C1768F	Pathogenic	0.854
BRCA1	P38398-1.2	C1768G	Pathogenic	0.868
BRCA1	P38398-1.2	C1768H	Pathogenic	0.852
BRCA1	P38398-1.2	C1768I	Pathogenic	0.761
BRCA1	P38398-1.2	C1768K	Pathogenic	0.892
BRCA1	P38398-1.2	C1768L	Pathogenic	0.761
BRCA1	P38398-1.2	C1768M	Pathogenic	0.763
BRCA1	P38398-1.2	C1768N	Pathogenic	0.777
BRCA1	P38398-1.2	C1768P	Pathogenic	0.758
BRCA1	P38398-1.2	C1768Q	Pathogenic	0.84
BRCA1	P38398-1.2	C1768R	Pathogenic	0.916
BRCA1	P38398-1.2	C1768S	Pathogenic	0.645
BRCA1	P38398-1.2	C1768T	Pathogenic	0.615
BRCA1	P38398-1.2	C1768V	Pathogenic	0.678
BRCA1	P38398-1.2	C1768W	Pathogenic	0.915
BRCA1	P38398-1.2	C1768Y	Pathogenic	0.871
BRCA1	P38398-1.2	Y1769A	Pathogenic	0.537
BRCA1	P38398-1.2	Y1769C	Neutral	0.435
BRCA1	P38398-1.2	Y1769D	Neutral	0.49
BRCA1	P38398-1.2	Y1769E	Neutral	0.31
BRCA1	P38398-1.2	Y1769F	Neutral	0.04
BRCA1	P38398-1.2	Y1769G	Pathogenic	0.717
BRCA1	P38398-1.2	Y1769H	Neutral	0.08
BRCA1	P38398-1.2	Y1769I	Neutral	0.185
BRCA1	P38398-1.2	Y1769K	Neutral	0.2
BRCA1	P38398-1.2	Y1769L	Neutral	0.185
BRCA1	P38398-1.2	Y1769M	Neutral	0.186
BRCA1	P38398-1.2	Y1769N	Neutral	0.375
BRCA1	P38398-1.2	Y1769P	Pathogenic	0.502
BRCA1	P38398-1.2	Y1769Q	Neutral	0.219
BRCA1	P38398-1.2	Y1769R	Neutral	0.203
BRCA1	P38398-1.2	Y1769S	Pathogenic	0.502
BRCA1	P38398-1.2	Y1769T	Neutral	0.394
BRCA1	P38398-1.2	Y1769V	Neutral	0.259
BRCA1	P38398-1.2	Y1769W	Neutral	0.078
BRCA1	P38398-1.2	G1770A	Neutral	0.242
BRCA1	P38398-1.2	G1770C	Pathogenic	0.589
BRCA1	P38398-1.2	G1770D	Neutral	0.438
BRCA1	P38398-1.2	G1770E	Pathogenic	0.626
BRCA1	P38398-1.2	G1770F	Pathogenic	0.808
BRCA1	P38398-1.2	G1770H	Pathogenic	0.674
BRCA1	P38398-1.2	G1770I	Pathogenic	0.825
BRCA1	P38398-1.2	G1770K	Pathogenic	0.748
BRCA1	P38398-1.2	G1770L	Pathogenic	0.826
BRCA1	P38398-1.2	G1770M	Pathogenic	0.769
BRCA1	P38398-1.2	G1770N	Neutral	0.377
BRCA1	P38398-1.2	G1770P	Pathogenic	0.523
BRCA1	P38398-1.2	G1770Q	Pathogenic	0.653
BRCA1	P38398-1.2	G1770R	Pathogenic	0.798
BRCA1	P38398-1.2	G1770S	Neutral	0.269
BRCA1	P38398-1.2	G1770T	Pathogenic	0.542
BRCA1	P38398-1.2	G1770V	Pathogenic	0.686
BRCA1	P38398-1.2	G1770W	Pathogenic	0.843
BRCA1	P38398-1.2	G1770Y	Pathogenic	0.83
BRCA1	P38398-1.2	P1771A	Pathogenic	0.545
BRCA1	P38398-1.2	P1771C	Pathogenic	0.62
BRCA1	P38398-1.2	P1771D	Neutral	0.418
BRCA1	P38398-1.2	P1771E	Pathogenic	0.518
BRCA1	P38398-1.2	P1771F	Pathogenic	0.852
BRCA1	P38398-1.2	P1771G	Pathogenic	0.723
BRCA1	P38398-1.2	P1771H	Pathogenic	0.657
BRCA1	P38398-1.2	P1771I	Pathogenic	0.757
BRCA1	P38398-1.2	P1771K	Pathogenic	0.655
BRCA1	P38398-1.2	P1771L	Pathogenic	0.758
BRCA1	P38398-1.2	P1771M	Pathogenic	0.687
BRCA1	P38398-1.2	P1771N	Pathogenic	0.537
BRCA1	P38398-1.2	P1771Q	Pathogenic	0.548
BRCA1	P38398-1.2	P1771R	Pathogenic	0.785
BRCA1	P38398-1.2	P1771S	Pathogenic	0.51
BRCA1	P38398-1.2	P1771T	Neutral	0.434
BRCA1	P38398-1.2	P1771V	Pathogenic	0.59
BRCA1	P38398-1.2	P1771W	Pathogenic	0.914
BRCA1	P38398-1.2	P1771Y	Pathogenic	0.822
BRCA1	P38398-1.2	F1772A	Pathogenic	0.879
BRCA1	P38398-1.2	F1772C	Pathogenic	0.829
BRCA1	P38398-1.2	F1772D	Pathogenic	0.858
BRCA1	P38398-1.2	F1772E	Pathogenic	0.802
BRCA1	P38398-1.2	F1772G	Pathogenic	0.941
BRCA1	P38398-1.2	F1772H	Pathogenic	0.619
BRCA1	P38398-1.2	F1772I	Pathogenic	0.505
BRCA1	P38398-1.2	F1772K	Pathogenic	0.693
BRCA1	P38398-1.2	F1772L	Pathogenic	0.505
BRCA1	P38398-1.2	F1772M	Pathogenic	0.502
BRCA1	P38398-1.2	F1772N	Pathogenic	0.844
BRCA1	P38398-1.2	F1772P	Pathogenic	0.901
BRCA1	P38398-1.2	F1772Q	Pathogenic	0.785
BRCA1	P38398-1.2	F1772R	Pathogenic	0.751
BRCA1	P38398-1.2	F1772S	Pathogenic	0.864
BRCA1	P38398-1.2	F1772T	Pathogenic	0.803
BRCA1	P38398-1.2	F1772V	Pathogenic	0.689
BRCA1	P38398-1.2	F1772W	Pathogenic	0.506
BRCA1	P38398-1.2	F1772Y	Neutral	0.232
BRCA1	P38398-1.2	T1773A	Pathogenic	0.547
BRCA1	P38398-1.2	T1773C	Pathogenic	0.529
BRCA1	P38398-1.2	T1773D	Pathogenic	0.5
BRCA1	P38398-1.2	T1773E	Pathogenic	0.578
BRCA1	P38398-1.2	T1773F	Pathogenic	0.776
BRCA1	P38398-1.2	T1773G	Pathogenic	0.792
BRCA1	P38398-1.2	T1773H	Pathogenic	0.71
BRCA1	P38398-1.2	T1773I	Pathogenic	0.654
BRCA1	P38398-1.2	T1773K	Pathogenic	0.708
BRCA1	P38398-1.2	T1773L	Pathogenic	0.654
BRCA1	P38398-1.2	T1773M	Pathogenic	0.656
BRCA1	P38398-1.2	T1773N	Neutral	0.416
BRCA1	P38398-1.2	T1773P	Pathogenic	0.508
BRCA1	P38398-1.2	T1773Q	Pathogenic	0.607
BRCA1	P38398-1.2	T1773R	Pathogenic	0.764
BRCA1	P38398-1.2	T1773S	Neutral	0.422
BRCA1	P38398-1.2	T1773V	Neutral	0.465
BRCA1	P38398-1.2	T1773W	Pathogenic	0.865
BRCA1	P38398-1.2	T1773Y	Pathogenic	0.801
BRCA1	P38398-1.2	N1774A	Neutral	0.375
BRCA1	P38398-1.2	N1774C	Neutral	0.358
BRCA1	P38398-1.2	N1774D	Neutral	0.107
BRCA1	P38398-1.2	N1774E	Neutral	0.171
BRCA1	P38398-1.2	N1774F	Pathogenic	0.512
BRCA1	P38398-1.2	N1774G	Neutral	0.308
BRCA1	P38398-1.2	N1774H	Neutral	0.147
BRCA1	P38398-1.2	N1774I	Neutral	0.451
BRCA1	P38398-1.2	N1774K	Neutral	0.268
BRCA1	P38398-1.2	N1774L	Neutral	0.451
BRCA1	P38398-1.2	N1774M	Neutral	0.366
BRCA1	P38398-1.2	N1774P	Neutral	0.263
BRCA1	P38398-1.2	N1774Q	Neutral	0.186
BRCA1	P38398-1.2	N1774R	Neutral	0.328
BRCA1	P38398-1.2	N1774S	Neutral	0.151
BRCA1	P38398-1.2	N1774T	Neutral	0.14
BRCA1	P38398-1.2	N1774V	Neutral	0.352
BRCA1	P38398-1.2	N1774W	Pathogenic	0.736
BRCA1	P38398-1.2	N1774Y	Neutral	0.458
BRCA1	P38398-1.2	M1775A	Pathogenic	0.877
BRCA1	P38398-1.2	M1775C	Pathogenic	0.826
BRCA1	P38398-1.2	M1775D	Pathogenic	0.895
BRCA1	P38398-1.2	M1775E	Pathogenic	0.799
BRCA1	P38398-1.2	M1775F	Pathogenic	0.642
BRCA1	P38398-1.2	M1775G	Pathogenic	0.957
BRCA1	P38398-1.2	M1775H	Pathogenic	0.767
BRCA1	P38398-1.2	M1775I	Neutral	0.494
BRCA1	P38398-1.2	M1775K	Pathogenic	0.715
BRCA1	P38398-1.2	M1775L	Neutral	0.405
BRCA1	P38398-1.2	M1775N	Pathogenic	0.841
BRCA1	P38398-1.2	M1775P	Pathogenic	0.861
BRCA1	P38398-1.2	M1775Q	Pathogenic	0.633
BRCA1	P38398-1.2	M1775R	Pathogenic	0.77
BRCA1	P38398-1.2	M1775S	Pathogenic	0.861
BRCA1	P38398-1.2	M1775T	Pathogenic	0.8
BRCA1	P38398-1.2	M1775V	Pathogenic	0.601
BRCA1	P38398-1.2	M1775W	Pathogenic	0.827
BRCA1	P38398-1.2	M1775Y	Pathogenic	0.748
BRCA1	P38398-1.2	P1776A	Neutral	0.177
BRCA1	P38398-1.2	P1776C	Neutral	0.226
BRCA1	P38398-1.2	P1776D	Neutral	0.114
BRCA1	P38398-1.2	P1776E	Neutral	0.162
BRCA1	P38398-1.2	P1776F	Pathogenic	0.507
BRCA1	P38398-1.2	P1776G	Neutral	0.319
BRCA1	P38398-1.2	P1776H	Neutral	0.256
BRCA1	P38398-1.2	P1776I	Neutral	0.359
BRCA1	P38398-1.2	P1776K	Neutral	0.254
BRCA1	P38398-1.2	P1776L	Neutral	0.359
BRCA1	P38398-1.2	P1776M	Neutral	0.282
BRCA1	P38398-1.2	P1776N	Neutral	0.172
BRCA1	P38398-1.2	P1776Q	Neutral	0.178
BRCA1	P38398-1.2	P1776R	Neutral	0.396
BRCA1	P38398-1.2	P1776S	Neutral	0.157
BRCA1	P38398-1.2	P1776T	Neutral	0.121
BRCA1	P38398-1.2	P1776V	Neutral	0.205
BRCA1	P38398-1.2	P1776W	Pathogenic	0.655
BRCA1	P38398-1.2	P1776Y	Neutral	0.453
BRCA1	P38398-1.2	T1777A	Neutral	0.163
BRCA1	P38398-1.2	T1777C	Neutral	0.153
BRCA1	P38398-1.2	T1777D	Neutral	0.139
BRCA1	P38398-1.2	T1777E	Neutral	0.18
BRCA1	P38398-1.2	T1777F	Neutral	0.358
BRCA1	P38398-1.2	T1777G	Neutral	0.379
BRCA1	P38398-1.2	T1777H	Neutral	0.282
BRCA1	P38398-1.2	T1777I	Neutral	0.233
BRCA1	P38398-1.2	T1777K	Neutral	0.28
BRCA1	P38398-1.2	T1777L	Neutral	0.233
BRCA1	P38398-1.2	T1777M	Neutral	0.235
BRCA1	P38398-1.2	T1777N	Neutral	0.103
BRCA1	P38398-1.2	T1777P	Neutral	0.143
BRCA1	P38398-1.2	T1777Q	Neutral	0.199
BRCA1	P38398-1.2	T1777R	Neutral	0.342
BRCA1	P38398-1.2	T1777S	Neutral	0.105
BRCA1	P38398-1.2	T1777V	Neutral	0.123
BRCA1	P38398-1.2	T1777W	Pathogenic	0.507
BRCA1	P38398-1.2	T1777Y	Neutral	0.393
BRCA1	P38398-1.2	D1778A	Neutral	0.353
BRCA1	P38398-1.2	D1778C	Neutral	0.337
BRCA1	P38398-1.2	D1778E	Neutral	0.102
BRCA1	P38398-1.2	D1778F	Pathogenic	0.543
BRCA1	P38398-1.2	D1778G	Neutral	0.368
BRCA1	P38398-1.2	D1778H	Neutral	0.289
BRCA1	P38398-1.2	D1778I	Neutral	0.482
BRCA1	P38398-1.2	D1778K	Neutral	0.375
BRCA1	P38398-1.2	D1778L	Pathogenic	0.573
BRCA1	P38398-1.2	D1778M	Neutral	0.485
BRCA1	P38398-1.2	D1778N	Neutral	0.109
BRCA1	P38398-1.2	D1778P	Neutral	0.184
BRCA1	P38398-1.2	D1778Q	Neutral	0.207
BRCA1	P38398-1.2	D1778R	Pathogenic	0.536
BRCA1	P38398-1.2	D1778S	Neutral	0.188
BRCA1	P38398-1.2	D1778T	Neutral	0.189
BRCA1	P38398-1.2	D1778V	Neutral	0.382
BRCA1	P38398-1.2	D1778W	Pathogenic	0.76
BRCA1	P38398-1.2	D1778Y	Pathogenic	0.58
BRCA1	P38398-1.2	Q1779A	Neutral	0.472
BRCA1	P38398-1.2	Q1779C	Pathogenic	0.545
BRCA1	P38398-1.2	Q1779D	Neutral	0.267
BRCA1	P38398-1.2	Q1779E	Neutral	0.106
BRCA1	P38398-1.2	Q1779F	Pathogenic	0.503
BRCA1	P38398-1.2	Q1779G	Pathogenic	0.664
BRCA1	P38398-1.2	Q1779H	Neutral	0.194
BRCA1	P38398-1.2	Q1779I	Neutral	0.442
BRCA1	P38398-1.2	Q1779K	Neutral	0.194
BRCA1	P38398-1.2	Q1779L	Neutral	0.355
BRCA1	P38398-1.2	Q1779M	Neutral	0.212
BRCA1	P38398-1.2	Q1779N	Neutral	0.247
BRCA1	P38398-1.2	Q1779P	Neutral	0.348
BRCA1	P38398-1.2	Q1779R	Neutral	0.244
BRCA1	P38398-1.2	Q1779S	Neutral	0.354
BRCA1	P38398-1.2	Q1779T	Neutral	0.335
BRCA1	P38398-1.2	Q1779V	Neutral	0.352
BRCA1	P38398-1.2	Q1779W	Pathogenic	0.565
BRCA1	P38398-1.2	Q1779Y	Neutral	0.362
BRCA1	P38398-1.2	L1780A	Pathogenic	0.733
BRCA1	P38398-1.2	L1780C	Pathogenic	0.646
BRCA1	P38398-1.2	L1780D	Pathogenic	0.825
BRCA1	P38398-1.2	L1780E	Pathogenic	0.687
BRCA1	P38398-1.2	L1780F	Neutral	0.414
BRCA1	P38398-1.2	L1780G	Pathogenic	0.926
BRCA1	P38398-1.2	L1780H	Pathogenic	0.646
BRCA1	P38398-1.2	L1780I	Neutral	0.211
BRCA1	P38398-1.2	L1780K	Pathogenic	0.581
BRCA1	P38398-1.2	L1780M	Neutral	0.209
BRCA1	P38398-1.2	L1780N	Pathogenic	0.746
BRCA1	P38398-1.2	L1780P	Pathogenic	0.775
BRCA1	P38398-1.2	L1780Q	Pathogenic	0.58
BRCA1	P38398-1.2	L1780R	Pathogenic	0.65
BRCA1	P38398-1.2	L1780S	Pathogenic	0.775
BRCA1	P38398-1.2	L1780T	Pathogenic	0.607
BRCA1	P38398-1.2	L1780V	Neutral	0.367
BRCA1	P38398-1.2	L1780W	Pathogenic	0.729
BRCA1	P38398-1.2	L1780Y	Pathogenic	0.534
BRCA1	P38398-1.2	E1781A	Pathogenic	0.632
BRCA1	P38398-1.2	E1781C	Pathogenic	0.768
BRCA1	P38398-1.2	E1781D	Neutral	0.256
BRCA1	P38398-1.2	E1781F	Pathogenic	0.708
BRCA1	P38398-1.2	E1781G	Pathogenic	0.791
BRCA1	P38398-1.2	E1781H	Neutral	0.365
BRCA1	P38398-1.2	E1781I	Pathogenic	0.655
BRCA1	P38398-1.2	E1781K	Neutral	0.37
BRCA1	P38398-1.2	E1781L	Pathogenic	0.655
BRCA1	P38398-1.2	E1781M	Pathogenic	0.571
BRCA1	P38398-1.2	E1781N	Neutral	0.389
BRCA1	P38398-1.2	E1781P	Pathogenic	0.505
BRCA1	P38398-1.2	E1781Q	Neutral	0.204
BRCA1	P38398-1.2	E1781R	Pathogenic	0.53
BRCA1	P38398-1.2	E1781S	Pathogenic	0.512
BRCA1	P38398-1.2	E1781T	Neutral	0.491
BRCA1	P38398-1.2	E1781V	Pathogenic	0.511
BRCA1	P38398-1.2	E1781W	Pathogenic	0.817
BRCA1	P38398-1.2	E1781Y	Pathogenic	0.661
BRCA1	P38398-1.2	W1782A	Pathogenic	0.939
BRCA1	P38398-1.2	W1782C	Pathogenic	0.877
BRCA1	P38398-1.2	W1782D	Pathogenic	0.927
BRCA1	P38398-1.2	W1782E	Pathogenic	0.856
BRCA1	P38398-1.2	W1782F	Neutral	0.45
BRCA1	P38398-1.2	W1782G	Pathogenic	0.942
BRCA1	P38398-1.2	W1782H	Pathogenic	0.775
BRCA1	P38398-1.2	W1782I	Pathogenic	0.817
BRCA1	P38398-1.2	W1782K	Pathogenic	0.769
BRCA1	P38398-1.2	W1782L	Pathogenic	0.756
BRCA1	P38398-1.2	W1782M	Pathogenic	0.681
BRCA1	P38398-1.2	W1782N	Pathogenic	0.92
BRCA1	P38398-1.2	W1782P	Pathogenic	0.931
BRCA1	P38398-1.2	W1782Q	Pathogenic	0.789
BRCA1	P38398-1.2	W1782R	Pathogenic	0.713
BRCA1	P38398-1.2	W1782S	Pathogenic	0.931
BRCA1	P38398-1.2	W1782T	Pathogenic	0.857
BRCA1	P38398-1.2	W1782V	Pathogenic	0.871
BRCA1	P38398-1.2	W1782Y	Neutral	0.329
BRCA1	P38398-1.2	M1783A	Pathogenic	0.686
BRCA1	P38398-1.2	M1783C	Pathogenic	0.592
BRCA1	P38398-1.2	M1783D	Pathogenic	0.722
BRCA1	P38398-1.2	M1783E	Pathogenic	0.548
BRCA1	P38398-1.2	M1783F	Neutral	0.355
BRCA1	P38398-1.2	M1783G	Pathogenic	0.873
BRCA1	P38398-1.2	M1783H	Pathogenic	0.502
BRCA1	P38398-1.2	M1783I	Neutral	0.23
BRCA1	P38398-1.2	M1783K	Neutral	0.434
BRCA1	P38398-1.2	M1783L	Neutral	0.172
BRCA1	P38398-1.2	M1783N	Pathogenic	0.618
BRCA1	P38398-1.2	M1783P	Pathogenic	0.655
BRCA1	P38398-1.2	M1783Q	Neutral	0.346
BRCA1	P38398-1.2	M1783R	Pathogenic	0.506
BRCA1	P38398-1.2	M1783S	Pathogenic	0.655
BRCA1	P38398-1.2	M1783T	Pathogenic	0.55
BRCA1	P38398-1.2	M1783V	Neutral	0.316
BRCA1	P38398-1.2	M1783W	Pathogenic	0.594
BRCA1	P38398-1.2	M1783Y	Neutral	0.476
BRCA1	P38398-1.2	V1784A	Neutral	0.095
BRCA1	P38398-1.2	V1784C	Neutral	0.091
BRCA1	P38398-1.2	V1784D	Neutral	0.152
BRCA1	P38398-1.2	V1784E	Neutral	0.091
BRCA1	P38398-1.2	V1784F	Neutral	0.113
BRCA1	P38398-1.2	V1784G	Neutral	0.321
BRCA1	P38398-1.2	V1784H	Neutral	0.152
BRCA1	P38398-1.2	V1784I	Neutral	0.023
BRCA1	P38398-1.2	V1784K	Neutral	0.151
BRCA1	P38398-1.2	V1784L	Neutral	0.046
BRCA1	P38398-1.2	V1784M	Neutral	0.046
BRCA1	P38398-1.2	V1784N	Neutral	0.139
BRCA1	P38398-1.2	V1784P	Neutral	0.116
BRCA1	P38398-1.2	V1784Q	Neutral	0.101
BRCA1	P38398-1.2	V1784R	Neutral	0.254
BRCA1	P38398-1.2	V1784S	Neutral	0.159
BRCA1	P38398-1.2	V1784T	Neutral	0.056
BRCA1	P38398-1.2	V1784W	Neutral	0.327
BRCA1	P38398-1.2	V1784Y	Neutral	0.127
BRCA1	P38398-1.2	Q1785A	Neutral	0.074
BRCA1	P38398-1.2	Q1785C	Neutral	0.097
BRCA1	P38398-1.2	Q1785D	Neutral	0.032
BRCA1	P38398-1.2	Q1785E	Neutral	0.011
BRCA1	P38398-1.2	Q1785F	Neutral	0.083
BRCA1	P38398-1.2	Q1785G	Neutral	0.151
BRCA1	P38398-1.2	Q1785H	Neutral	0.021
BRCA1	P38398-1.2	Q1785I	Neutral	0.066
BRCA1	P38398-1.2	Q1785K	Neutral	0.021
BRCA1	P38398-1.2	Q1785L	Neutral	0.047
BRCA1	P38398-1.2	Q1785M	Neutral	0.024
BRCA1	P38398-1.2	Q1785N	Neutral	0.029
BRCA1	P38398-1.2	Q1785P	Neutral	0.046
BRCA1	P38398-1.2	Q1785R	Neutral	0.028
BRCA1	P38398-1.2	Q1785S	Neutral	0.047
BRCA1	P38398-1.2	Q1785T	Neutral	0.043
BRCA1	P38398-1.2	Q1785V	Neutral	0.047
BRCA1	P38398-1.2	Q1785W	Neutral	0.104
BRCA1	P38398-1.2	Q1785Y	Neutral	0.048
BRCA1	P38398-1.2	L1786A	Pathogenic	0.633
BRCA1	P38398-1.2	L1786C	Pathogenic	0.534
BRCA1	P38398-1.2	L1786D	Pathogenic	0.747
BRCA1	P38398-1.2	L1786E	Pathogenic	0.58
BRCA1	P38398-1.2	L1786F	Neutral	0.307
BRCA1	P38398-1.2	L1786G	Pathogenic	0.886
BRCA1	P38398-1.2	L1786H	Pathogenic	0.535
BRCA1	P38398-1.2	L1786I	Neutral	0.143
BRCA1	P38398-1.2	L1786K	Neutral	0.466
BRCA1	P38398-1.2	L1786M	Neutral	0.143
BRCA1	P38398-1.2	L1786N	Pathogenic	0.649
BRCA1	P38398-1.2	L1786P	Pathogenic	0.684
BRCA1	P38398-1.2	L1786Q	Neutral	0.464
BRCA1	P38398-1.2	L1786R	Pathogenic	0.538
BRCA1	P38398-1.2	L1786S	Pathogenic	0.684
BRCA1	P38398-1.2	L1786T	Neutral	0.492
BRCA1	P38398-1.2	L1786V	Neutral	0.267
BRCA1	P38398-1.2	L1786W	Pathogenic	0.629
BRCA1	P38398-1.2	L1786Y	Neutral	0.418
BRCA1	P38398-1.2	C1787A	Pathogenic	0.648
BRCA1	P38398-1.2	C1787D	Pathogenic	0.797
BRCA1	P38398-1.2	C1787E	Pathogenic	0.894
BRCA1	P38398-1.2	C1787F	Pathogenic	0.881
BRCA1	P38398-1.2	C1787G	Pathogenic	0.893
BRCA1	P38398-1.2	C1787H	Pathogenic	0.879
BRCA1	P38398-1.2	C1787I	Pathogenic	0.801
BRCA1	P38398-1.2	C1787K	Pathogenic	0.912
BRCA1	P38398-1.2	C1787L	Pathogenic	0.801
BRCA1	P38398-1.2	C1787M	Pathogenic	0.803
BRCA1	P38398-1.2	C1787N	Pathogenic	0.815
BRCA1	P38398-1.2	C1787P	Pathogenic	0.798
BRCA1	P38398-1.2	C1787Q	Pathogenic	0.869
BRCA1	P38398-1.2	C1787R	Pathogenic	0.933
BRCA1	P38398-1.2	C1787S	Pathogenic	0.697
BRCA1	P38398-1.2	C1787T	Pathogenic	0.67
BRCA1	P38398-1.2	C1787V	Pathogenic	0.728
BRCA1	P38398-1.2	C1787W	Pathogenic	0.932
BRCA1	P38398-1.2	C1787Y	Pathogenic	0.896
BRCA1	P38398-1.2	G1788A	Pathogenic	0.54
BRCA1	P38398-1.2	G1788C	Pathogenic	0.841
BRCA1	P38398-1.2	G1788D	Pathogenic	0.741
BRCA1	P38398-1.2	G1788E	Pathogenic	0.86
BRCA1	P38398-1.2	G1788F	Pathogenic	0.939
BRCA1	P38398-1.2	G1788H	Pathogenic	0.883
BRCA1	P38398-1.2	G1788I	Pathogenic	0.946
BRCA1	P38398-1.2	G1788K	Pathogenic	0.916
BRCA1	P38398-1.2	G1788L	Pathogenic	0.946
BRCA1	P38398-1.2	G1788M	Pathogenic	0.924
BRCA1	P38398-1.2	G1788N	Pathogenic	0.69
BRCA1	P38398-1.2	G1788P	Pathogenic	0.801
BRCA1	P38398-1.2	G1788Q	Pathogenic	0.874
BRCA1	P38398-1.2	G1788R	Pathogenic	0.936
BRCA1	P38398-1.2	G1788S	Pathogenic	0.574
BRCA1	P38398-1.2	G1788T	Pathogenic	0.813
BRCA1	P38398-1.2	G1788V	Pathogenic	0.889
BRCA1	P38398-1.2	G1788W	Pathogenic	0.952
BRCA1	P38398-1.2	G1788Y	Pathogenic	0.947
BRCA1	P38398-1.2	A1789C	Pathogenic	0.527
BRCA1	P38398-1.2	A1789D	Pathogenic	0.719
BRCA1	P38398-1.2	A1789E	Pathogenic	0.727
BRCA1	P38398-1.2	A1789F	Pathogenic	0.871
BRCA1	P38398-1.2	A1789G	Pathogenic	0.529
BRCA1	P38398-1.2	A1789H	Pathogenic	0.826
BRCA1	P38398-1.2	A1789I	Pathogenic	0.786
BRCA1	P38398-1.2	A1789K	Pathogenic	0.825
BRCA1	P38398-1.2	A1789L	Pathogenic	0.786
BRCA1	P38398-1.2	A1789M	Pathogenic	0.788
BRCA1	P38398-1.2	A1789N	Pathogenic	0.742
BRCA1	P38398-1.2	A1789P	Pathogenic	0.638
BRCA1	P38398-1.2	A1789Q	Pathogenic	0.75
BRCA1	P38398-1.2	A1789R	Pathogenic	0.863
BRCA1	P38398-1.2	A1789S	Neutral	0.369
BRCA1	P38398-1.2	A1789T	Pathogenic	0.569
BRCA1	P38398-1.2	A1789V	Pathogenic	0.628
BRCA1	P38398-1.2	A1789W	Pathogenic	0.947
BRCA1	P38398-1.2	A1789Y	Pathogenic	0.887
BRCA1	P38398-1.2	S1790A	Neutral	0.151
BRCA1	P38398-1.2	S1790C	Neutral	0.299
BRCA1	P38398-1.2	S1790D	Neutral	0.25
BRCA1	P38398-1.2	S1790E	Neutral	0.332
BRCA1	P38398-1.2	S1790F	Pathogenic	0.642
BRCA1	P38398-1.2	S1790G	Neutral	0.283
BRCA1	P38398-1.2	S1790H	Neutral	0.469
BRCA1	P38398-1.2	S1790I	Pathogenic	0.584
BRCA1	P38398-1.2	S1790K	Neutral	0.468
BRCA1	P38398-1.2	S1790L	Pathogenic	0.585
BRCA1	P38398-1.2	S1790M	Neutral	0.497
BRCA1	P38398-1.2	S1790N	Neutral	0.206
BRCA1	P38398-1.2	S1790P	Neutral	0.319
BRCA1	P38398-1.2	S1790Q	Neutral	0.359
BRCA1	P38398-1.2	S1790R	Pathogenic	0.628
BRCA1	P38398-1.2	S1790T	Neutral	0.196
BRCA1	P38398-1.2	S1790V	Neutral	0.482
BRCA1	P38398-1.2	S1790W	Pathogenic	0.827
BRCA1	P38398-1.2	S1790Y	Pathogenic	0.676
BRCA1	P38398-1.2	V1791A	Pathogenic	0.75
BRCA1	P38398-1.2	V1791C	Pathogenic	0.741
BRCA1	P38398-1.2	V1791D	Pathogenic	0.837
BRCA1	P38398-1.2	V1791E	Pathogenic	0.741
BRCA1	P38398-1.2	V1791F	Pathogenic	0.784
BRCA1	P38398-1.2	V1791G	Pathogenic	0.931
BRCA1	P38398-1.2	V1791H	Pathogenic	0.836
BRCA1	P38398-1.2	V1791I	Neutral	0.399
BRCA1	P38398-1.2	V1791K	Pathogenic	0.835
BRCA1	P38398-1.2	V1791L	Pathogenic	0.579
BRCA1	P38398-1.2	V1791M	Pathogenic	0.581
BRCA1	P38398-1.2	V1791N	Pathogenic	0.822
BRCA1	P38398-1.2	V1791P	Pathogenic	0.79
BRCA1	P38398-1.2	V1791Q	Pathogenic	0.763
BRCA1	P38398-1.2	V1791R	Pathogenic	0.907
BRCA1	P38398-1.2	V1791S	Pathogenic	0.844
BRCA1	P38398-1.2	V1791T	Pathogenic	0.627
BRCA1	P38398-1.2	V1791W	Pathogenic	0.933
BRCA1	P38398-1.2	V1791Y	Pathogenic	0.807
BRCA1	P38398-1.2	V1792A	Pathogenic	0.614
BRCA1	P38398-1.2	V1792C	Pathogenic	0.603
BRCA1	P38398-1.2	V1792D	Pathogenic	0.731
BRCA1	P38398-1.2	V1792E	Pathogenic	0.603
BRCA1	P38398-1.2	V1792F	Pathogenic	0.658
BRCA1	P38398-1.2	V1792G	Pathogenic	0.878
BRCA1	P38398-1.2	V1792H	Pathogenic	0.73
BRCA1	P38398-1.2	V1792I	Neutral	0.26
BRCA1	P38398-1.2	V1792K	Pathogenic	0.729
BRCA1	P38398-1.2	V1792L	Neutral	0.422
BRCA1	P38398-1.2	V1792M	Neutral	0.424
BRCA1	P38398-1.2	V1792N	Pathogenic	0.709
BRCA1	P38398-1.2	V1792P	Pathogenic	0.665
BRCA1	P38398-1.2	V1792Q	Pathogenic	0.631
BRCA1	P38398-1.2	V1792R	Pathogenic	0.838
BRCA1	P38398-1.2	V1792S	Pathogenic	0.741
BRCA1	P38398-1.2	V1792T	Neutral	0.471
BRCA1	P38398-1.2	V1792W	Pathogenic	0.88
BRCA1	P38398-1.2	V1792Y	Pathogenic	0.689
BRCA1	P38398-1.2	K1793A	Neutral	0.288
BRCA1	P38398-1.2	K1793C	Neutral	0.352
BRCA1	P38398-1.2	K1793D	Neutral	0.195
BRCA1	P38398-1.2	K1793E	Neutral	0.073
BRCA1	P38398-1.2	K1793F	Neutral	0.152
BRCA1	P38398-1.2	K1793G	Neutral	0.472
BRCA1	P38398-1.2	K1793H	Neutral	0.116
BRCA1	P38398-1.2	K1793I	Neutral	0.187
BRCA1	P38398-1.2	K1793L	Neutral	0.138
BRCA1	P38398-1.2	K1793M	Neutral	0.101
BRCA1	P38398-1.2	K1793N	Neutral	0.131
BRCA1	P38398-1.2	K1793P	Neutral	0.194
BRCA1	P38398-1.2	K1793Q	Neutral	0.065
BRCA1	P38398-1.2	K1793R	Neutral	0.039
BRCA1	P38398-1.2	K1793S	Neutral	0.199
BRCA1	P38398-1.2	K1793T	Neutral	0.185
BRCA1	P38398-1.2	K1793V	Neutral	0.197
BRCA1	P38398-1.2	K1793W	Neutral	0.249
BRCA1	P38398-1.2	K1793Y	Neutral	0.127
BRCA1	P38398-1.2	E1794A	Neutral	0.29
BRCA1	P38398-1.2	E1794C	Neutral	0.441
BRCA1	P38398-1.2	E1794D	Neutral	0.076
BRCA1	P38398-1.2	E1794F	Neutral	0.366
BRCA1	P38398-1.2	E1794G	Neutral	0.474
BRCA1	P38398-1.2	E1794H	Neutral	0.12
BRCA1	P38398-1.2	E1794I	Neutral	0.311
BRCA1	P38398-1.2	E1794K	Neutral	0.123
BRCA1	P38398-1.2	E1794L	Neutral	0.311
BRCA1	P38398-1.2	E1794M	Neutral	0.241
BRCA1	P38398-1.2	E1794N	Neutral	0.132
BRCA1	P38398-1.2	E1794P	Neutral	0.196
BRCA1	P38398-1.2	E1794Q	Neutral	0.057
BRCA1	P38398-1.2	E1794R	Neutral	0.212
BRCA1	P38398-1.2	E1794S	Neutral	0.2
BRCA1	P38398-1.2	E1794T	Neutral	0.187
BRCA1	P38398-1.2	E1794V	Neutral	0.199
BRCA1	P38398-1.2	E1794W	Pathogenic	0.515
BRCA1	P38398-1.2	E1794Y	Neutral	0.317
BRCA1	P38398-1.2	L1795A	Neutral	0.102
BRCA1	P38398-1.2	L1795C	Neutral	0.07
BRCA1	P38398-1.2	L1795D	Neutral	0.164
BRCA1	P38398-1.2	L1795E	Neutral	0.084
BRCA1	P38398-1.2	L1795F	Neutral	0.028
BRCA1	P38398-1.2	L1795G	Neutral	0.34
BRCA1	P38398-1.2	L1795H	Neutral	0.071
BRCA1	P38398-1.2	L1795I	Neutral	0.011
BRCA1	P38398-1.2	L1795K	Neutral	0.055
BRCA1	P38398-1.2	L1795M	Neutral	0.011
BRCA1	P38398-1.2	L1795N	Neutral	0.109
BRCA1	P38398-1.2	L1795P	Neutral	0.125
BRCA1	P38398-1.2	L1795Q	Neutral	0.054
BRCA1	P38398-1.2	L1795R	Neutral	0.071
BRCA1	P38398-1.2	L1795S	Neutral	0.125
BRCA1	P38398-1.2	L1795T	Neutral	0.06
BRCA1	P38398-1.2	L1795V	Neutral	0.024
BRCA1	P38398-1.2	L1795W	Neutral	0.101
BRCA1	P38398-1.2	L1795Y	Neutral	0.045
BRCA1	P38398-1.2	S1796A	Neutral	0.061
BRCA1	P38398-1.2	S1796C	Neutral	0.134
BRCA1	P38398-1.2	S1796D	Neutral	0.108
BRCA1	P38398-1.2	S1796E	Neutral	0.154
BRCA1	P38398-1.2	S1796F	Neutral	0.395
BRCA1	P38398-1.2	S1796G	Neutral	0.126
BRCA1	P38398-1.2	S1796H	Neutral	0.243
BRCA1	P38398-1.2	S1796I	Neutral	0.339
BRCA1	P38398-1.2	S1796K	Neutral	0.243
BRCA1	P38398-1.2	S1796L	Neutral	0.339
BRCA1	P38398-1.2	S1796M	Neutral	0.265
BRCA1	P38398-1.2	S1796N	Neutral	0.086
BRCA1	P38398-1.2	S1796P	Neutral	0.146
BRCA1	P38398-1.2	S1796Q	Neutral	0.17
BRCA1	P38398-1.2	S1796R	Neutral	0.381
BRCA1	P38398-1.2	S1796T	Neutral	0.082
BRCA1	P38398-1.2	S1796V	Neutral	0.253
BRCA1	P38398-1.2	S1796W	Pathogenic	0.635
BRCA1	P38398-1.2	S1796Y	Neutral	0.431
BRCA1	P38398-1.2	S1797A	Neutral	0.007
BRCA1	P38398-1.2	S1797C	Neutral	0.017
BRCA1	P38398-1.2	S1797D	Neutral	0.013
BRCA1	P38398-1.2	S1797E	Neutral	0.02
BRCA1	P38398-1.2	S1797F	Neutral	0.067
BRCA1	P38398-1.2	S1797G	Neutral	0.016
BRCA1	P38398-1.2	S1797H	Neutral	0.034
BRCA1	P38398-1.2	S1797I	Neutral	0.053
BRCA1	P38398-1.2	S1797K	Neutral	0.034
BRCA1	P38398-1.2	S1797L	Neutral	0.053
BRCA1	P38398-1.2	S1797M	Neutral	0.038
BRCA1	P38398-1.2	S1797N	Neutral	0.01
BRCA1	P38398-1.2	S1797P	Neutral	0.018
BRCA1	P38398-1.2	S1797Q	Neutral	0.022
BRCA1	P38398-1.2	S1797R	Neutral	0.063
BRCA1	P38398-1.2	S1797T	Neutral	0.01
BRCA1	P38398-1.2	S1797V	Neutral	0.036
BRCA1	P38398-1.2	S1797W	Neutral	0.16
BRCA1	P38398-1.2	S1797Y	Neutral	0.077
BRCA1	P38398-1.2	F1798A	Neutral	0.327
BRCA1	P38398-1.2	F1798C	Neutral	0.244
BRCA1	P38398-1.2	F1798D	Neutral	0.286
BRCA1	P38398-1.2	F1798E	Neutral	0.212
BRCA1	P38398-1.2	F1798G	Pathogenic	0.514
BRCA1	P38398-1.2	F1798H	Neutral	0.098
BRCA1	P38398-1.2	F1798I	Neutral	0.064
BRCA1	P38398-1.2	F1798K	Neutral	0.131
BRCA1	P38398-1.2	F1798L	Neutral	0.063
BRCA1	P38398-1.2	F1798M	Neutral	0.063
BRCA1	P38398-1.2	F1798N	Neutral	0.265
BRCA1	P38398-1.2	F1798P	Neutral	0.378
BRCA1	P38398-1.2	F1798Q	Neutral	0.196
BRCA1	P38398-1.2	F1798R	Neutral	0.167
BRCA1	P38398-1.2	F1798S	Neutral	0.297
BRCA1	P38398-1.2	F1798T	Neutral	0.214
BRCA1	P38398-1.2	F1798V	Neutral	0.128
BRCA1	P38398-1.2	F1798W	Neutral	0.064
BRCA1	P38398-1.2	F1798Y	Neutral	0.02
BRCA1	P38398-1.2	T1799A	Neutral	0.027
BRCA1	P38398-1.2	T1799C	Neutral	0.026
BRCA1	P38398-1.2	T1799D	Neutral	0.023
BRCA1	P38398-1.2	T1799E	Neutral	0.031
BRCA1	P38398-1.2	T1799F	Neutral	0.075
BRCA1	P38398-1.2	T1799G	Neutral	0.082
BRCA1	P38398-1.2	T1799H	Neutral	0.054
BRCA1	P38398-1.2	T1799I	Neutral	0.042
BRCA1	P38398-1.2	T1799K	Neutral	0.054
BRCA1	P38398-1.2	T1799L	Neutral	0.042
BRCA1	P38398-1.2	T1799M	Neutral	0.043
BRCA1	P38398-1.2	T1799N	Neutral	0.016
BRCA1	P38398-1.2	T1799P	Neutral	0.024
BRCA1	P38398-1.2	T1799Q	Neutral	0.035
BRCA1	P38398-1.2	T1799R	Neutral	0.07
BRCA1	P38398-1.2	T1799S	Neutral	0.017
BRCA1	P38398-1.2	T1799V	Neutral	0.02
BRCA1	P38398-1.2	T1799W	Neutral	0.13
BRCA1	P38398-1.2	T1799Y	Neutral	0.086
BRCA1	P38398-1.2	L1800A	Neutral	0.011
BRCA1	P38398-1.2	L1800C	Neutral	0.007
BRCA1	P38398-1.2	L1800D	Neutral	0.018
BRCA1	P38398-1.2	L1800E	Neutral	0.009
BRCA1	P38398-1.2	L1800F	Neutral	0.003
BRCA1	P38398-1.2	L1800G	Neutral	0.047
BRCA1	P38398-1.2	L1800H	Neutral	0.007
BRCA1	P38398-1.2	L1800I	Neutral	0.001
BRCA1	P38398-1.2	L1800K	Neutral	0.005
BRCA1	P38398-1.2	L1800M	Neutral	0.001
BRCA1	P38398-1.2	L1800N	Neutral	0.012
BRCA1	P38398-1.2	L1800P	Neutral	0.013
BRCA1	P38398-1.2	L1800Q	Neutral	0.005
BRCA1	P38398-1.2	L1800R	Neutral	0.007
BRCA1	P38398-1.2	L1800S	Neutral	0.013
BRCA1	P38398-1.2	L1800T	Neutral	0.006
BRCA1	P38398-1.2	L1800V	Neutral	0.002
BRCA1	P38398-1.2	L1800W	Neutral	0.011
BRCA1	P38398-1.2	L1800Y	Neutral	0.005
BRCA1	P38398-1.2	G1801A	Neutral	0.009
BRCA1	P38398-1.2	G1801C	Neutral	0.039
BRCA1	P38398-1.2	G1801D	Neutral	0.021
BRCA1	P38398-1.2	G1801E	Neutral	0.045
BRCA1	P38398-1.2	G1801F	Neutral	0.105
BRCA1	P38398-1.2	G1801H	Neutral	0.055
BRCA1	P38398-1.2	G1801I	Neutral	0.117
BRCA1	P38398-1.2	G1801K	Neutral	0.077
BRCA1	P38398-1.2	G1801L	Neutral	0.117
BRCA1	P38398-1.2	G1801M	Neutral	0.085
BRCA1	P38398-1.2	G1801N	Neutral	0.017
BRCA1	P38398-1.2	G1801P	Neutral	0.03
BRCA1	P38398-1.2	G1801Q	Neutral	0.05
BRCA1	P38398-1.2	G1801R	Neutral	0.1
BRCA1	P38398-1.2	G1801S	Neutral	0.01
BRCA1	P38398-1.2	G1801T	Neutral	0.032
BRCA1	P38398-1.2	G1801V	Neutral	0.058
BRCA1	P38398-1.2	G1801W	Neutral	0.131
BRCA1	P38398-1.2	G1801Y	Neutral	0.12
BRCA1	P38398-1.2	T1802A	Neutral	0.004
BRCA1	P38398-1.2	T1802C	Neutral	0.004
BRCA1	P38398-1.2	T1802D	Neutral	0.004
BRCA1	P38398-1.2	T1802E	Neutral	0.005
BRCA1	P38398-1.2	T1802F	Neutral	0.013
BRCA1	P38398-1.2	T1802G	Neutral	0.014
BRCA1	P38398-1.2	T1802H	Neutral	0.009
BRCA1	P38398-1.2	T1802I	Neutral	0.007
BRCA1	P38398-1.2	T1802K	Neutral	0.009
BRCA1	P38398-1.2	T1802L	Neutral	0.007
BRCA1	P38398-1.2	T1802M	Neutral	0.007
BRCA1	P38398-1.2	T1802N	Neutral	0.003
BRCA1	P38398-1.2	T1802P	Neutral	0.004
BRCA1	P38398-1.2	T1802Q	Neutral	0.006
BRCA1	P38398-1.2	T1802R	Neutral	0.012
BRCA1	P38398-1.2	T1802S	Neutral	0.003
BRCA1	P38398-1.2	T1802V	Neutral	0.003
BRCA1	P38398-1.2	T1802W	Neutral	0.023
BRCA1	P38398-1.2	T1802Y	Neutral	0.015
BRCA1	P38398-1.2	G1803A	Neutral	0.081
BRCA1	P38398-1.2	G1803C	Neutral	0.285
BRCA1	P38398-1.2	G1803D	Neutral	0.177
BRCA1	P38398-1.2	G1803E	Neutral	0.317
BRCA1	P38398-1.2	G1803F	Pathogenic	0.538
BRCA1	P38398-1.2	G1803H	Neutral	0.364
BRCA1	P38398-1.2	G1803I	Pathogenic	0.567
BRCA1	P38398-1.2	G1803K	Neutral	0.451
BRCA1	P38398-1.2	G1803L	Pathogenic	0.568
BRCA1	P38398-1.2	G1803M	Neutral	0.48
BRCA1	P38398-1.2	G1803N	Neutral	0.144
BRCA1	P38398-1.2	G1803P	Neutral	0.233
BRCA1	P38398-1.2	G1803Q	Neutral	0.343
BRCA1	P38398-1.2	G1803R	Pathogenic	0.523
BRCA1	P38398-1.2	G1803S	Neutral	0.092
BRCA1	P38398-1.2	G1803T	Neutral	0.247
BRCA1	P38398-1.2	G1803V	Neutral	0.377
BRCA1	P38398-1.2	G1803W	Pathogenic	0.599
BRCA1	P38398-1.2	G1803Y	Pathogenic	0.575
BRCA1	P38398-1.2	V1804A	Neutral	0.003
BRCA1	P38398-1.2	V1804C	Neutral	0.003
BRCA1	P38398-1.2	V1804D	Neutral	0.006
BRCA1	P38398-1.2	V1804E	Neutral	0.003
BRCA1	P38398-1.2	V1804F	Neutral	0.004
BRCA1	P38398-1.2	V1804G	Neutral	0.015
BRCA1	P38398-1.2	V1804H	Neutral	0.006
BRCA1	P38398-1.2	V1804I	Neutral	0.001
BRCA1	P38398-1.2	V1804K	Neutral	0.006
BRCA1	P38398-1.2	V1804L	Neutral	0.002
BRCA1	P38398-1.2	V1804M	Neutral	0.002
BRCA1	P38398-1.2	V1804N	Neutral	0.005
BRCA1	P38398-1.2	V1804P	Neutral	0.004
BRCA1	P38398-1.2	V1804Q	Neutral	0.004
BRCA1	P38398-1.2	V1804R	Neutral	0.011
BRCA1	P38398-1.2	V1804S	Neutral	0.006
BRCA1	P38398-1.2	V1804T	Neutral	0.002
BRCA1	P38398-1.2	V1804W	Neutral	0.016
BRCA1	P38398-1.2	V1804Y	Neutral	0.005
BRCA1	P38398-1.2	H1805A	Neutral	0.125
BRCA1	P38398-1.2	H1805C	Neutral	0.117
BRCA1	P38398-1.2	H1805D	Neutral	0.054
BRCA1	P38398-1.2	H1805E	Neutral	0.026
BRCA1	P38398-1.2	H1805F	Neutral	0.043
BRCA1	P38398-1.2	H1805G	Neutral	0.179
BRCA1	P38398-1.2	H1805I	Neutral	0.068
BRCA1	P38398-1.2	H1805K	Neutral	0.044
BRCA1	P38398-1.2	H1805L	Neutral	0.069
BRCA1	P38398-1.2	H1805M	Neutral	0.049
BRCA1	P38398-1.2	H1805N	Neutral	0.024
BRCA1	P38398-1.2	H1805P	Neutral	0.078
BRCA1	P38398-1.2	H1805Q	Neutral	0.024
BRCA1	P38398-1.2	H1805R	Neutral	0.041
BRCA1	P38398-1.2	H1805S	Neutral	0.08
BRCA1	P38398-1.2	H1805T	Neutral	0.074
BRCA1	P38398-1.2	H1805V	Neutral	0.08
BRCA1	P38398-1.2	H1805W	Neutral	0.108
BRCA1	P38398-1.2	H1805Y	Neutral	0.017
BRCA1	P38398-1.2	P1806A	Neutral	0.099
BRCA1	P38398-1.2	P1806C	Neutral	0.131
BRCA1	P38398-1.2	P1806D	Neutral	0.062
BRCA1	P38398-1.2	P1806E	Neutral	0.09
BRCA1	P38398-1.2	P1806F	Neutral	0.346
BRCA1	P38398-1.2	P1806G	Neutral	0.194
BRCA1	P38398-1.2	P1806H	Neutral	0.15
BRCA1	P38398-1.2	P1806I	Neutral	0.223
BRCA1	P38398-1.2	P1806K	Neutral	0.149
BRCA1	P38398-1.2	P1806L	Neutral	0.224
BRCA1	P38398-1.2	P1806M	Neutral	0.168
BRCA1	P38398-1.2	P1806N	Neutral	0.097
BRCA1	P38398-1.2	P1806Q	Neutral	0.1
BRCA1	P38398-1.2	P1806R	Neutral	0.252
BRCA1	P38398-1.2	P1806S	Neutral	0.087
BRCA1	P38398-1.2	P1806T	Neutral	0.066
BRCA1	P38398-1.2	P1806V	Neutral	0.117
BRCA1	P38398-1.2	P1806W	Neutral	0.494
BRCA1	P38398-1.2	P1806Y	Neutral	0.299
BRCA1	P38398-1.2	I1807A	Neutral	0.186
BRCA1	P38398-1.2	I1807C	Neutral	0.132
BRCA1	P38398-1.2	I1807D	Neutral	0.214
BRCA1	P38398-1.2	I1807E	Neutral	0.155
BRCA1	P38398-1.2	I1807F	Neutral	0.056
BRCA1	P38398-1.2	I1807G	Pathogenic	0.508
BRCA1	P38398-1.2	I1807H	Neutral	0.132
BRCA1	P38398-1.2	I1807K	Neutral	0.143
BRCA1	P38398-1.2	I1807L	Neutral	0.022
BRCA1	P38398-1.2	I1807M	Neutral	0.031
BRCA1	P38398-1.2	I1807N	Neutral	0.197
BRCA1	P38398-1.2	I1807P	Neutral	0.223
BRCA1	P38398-1.2	I1807Q	Neutral	0.142
BRCA1	P38398-1.2	I1807R	Neutral	0.182
BRCA1	P38398-1.2	I1807S	Neutral	0.223
BRCA1	P38398-1.2	I1807T	Neutral	0.114
BRCA1	P38398-1.2	I1807V	Neutral	0.023
BRCA1	P38398-1.2	I1807W	Neutral	0.245
BRCA1	P38398-1.2	I1807Y	Neutral	0.087
BRCA1	P38398-1.2	V1808A	Pathogenic	0.606
BRCA1	P38398-1.2	V1808C	Pathogenic	0.596
BRCA1	P38398-1.2	V1808D	Pathogenic	0.725
BRCA1	P38398-1.2	V1808E	Pathogenic	0.595
BRCA1	P38398-1.2	V1808F	Pathogenic	0.651
BRCA1	P38398-1.2	V1808G	Pathogenic	0.874
BRCA1	P38398-1.2	V1808H	Pathogenic	0.724
BRCA1	P38398-1.2	V1808I	Neutral	0.254
BRCA1	P38398-1.2	V1808K	Pathogenic	0.723
BRCA1	P38398-1.2	V1808L	Neutral	0.414
BRCA1	P38398-1.2	V1808M	Neutral	0.417
BRCA1	P38398-1.2	V1808N	Pathogenic	0.703
BRCA1	P38398-1.2	V1808P	Pathogenic	0.659
BRCA1	P38398-1.2	V1808Q	Pathogenic	0.624
BRCA1	P38398-1.2	V1808R	Pathogenic	0.833
BRCA1	P38398-1.2	V1808S	Pathogenic	0.735
BRCA1	P38398-1.2	V1808T	Neutral	0.463
BRCA1	P38398-1.2	V1808W	Pathogenic	0.877
BRCA1	P38398-1.2	V1808Y	Pathogenic	0.682
BRCA1	P38398-1.2	V1809A	Neutral	0.292
BRCA1	P38398-1.2	V1809C	Neutral	0.283
BRCA1	P38398-1.2	V1809D	Neutral	0.414
BRCA1	P38398-1.2	V1809E	Neutral	0.283
BRCA1	P38398-1.2	V1809F	Neutral	0.334
BRCA1	P38398-1.2	V1809G	Pathogenic	0.651
BRCA1	P38398-1.2	V1809H	Neutral	0.413
BRCA1	P38398-1.2	V1809I	Neutral	0.084
BRCA1	P38398-1.2	V1809K	Neutral	0.411
BRCA1	P38398-1.2	V1809L	Neutral	0.159
BRCA1	P38398-1.2	V1809M	Neutral	0.161
BRCA1	P38398-1.2	V1809N	Neutral	0.388
BRCA1	P38398-1.2	V1809P	Neutral	0.341
BRCA1	P38398-1.2	V1809Q	Neutral	0.308
BRCA1	P38398-1.2	V1809R	Pathogenic	0.573
BRCA1	P38398-1.2	V1809S	Neutral	0.426
BRCA1	P38398-1.2	V1809T	Neutral	0.188
BRCA1	P38398-1.2	V1809W	Pathogenic	0.657
BRCA1	P38398-1.2	V1809Y	Neutral	0.365
BRCA1	P38398-1.2	V1810A	Neutral	0.036
BRCA1	P38398-1.2	V1810C	Neutral	0.035
BRCA1	P38398-1.2	V1810D	Neutral	0.06
BRCA1	P38398-1.2	V1810E	Neutral	0.035
BRCA1	P38398-1.2	V1810F	Neutral	0.043
BRCA1	P38398-1.2	V1810G	Neutral	0.145
BRCA1	P38398-1.2	V1810H	Neutral	0.06
BRCA1	P38398-1.2	V1810I	Neutral	0.008
BRCA1	P38398-1.2	V1810K	Neutral	0.06
BRCA1	P38398-1.2	V1810L	Neutral	0.017
BRCA1	P38398-1.2	V1810M	Neutral	0.017
BRCA1	P38398-1.2	V1810N	Neutral	0.054
BRCA1	P38398-1.2	V1810P	Neutral	0.045
BRCA1	P38398-1.2	V1810Q	Neutral	0.039
BRCA1	P38398-1.2	V1810R	Neutral	0.108
BRCA1	P38398-1.2	V1810S	Neutral	0.063
BRCA1	P38398-1.2	V1810T	Neutral	0.021
BRCA1	P38398-1.2	V1810W	Neutral	0.148
BRCA1	P38398-1.2	V1810Y	Neutral	0.05
BRCA1	P38398-1.2	Q1811A	Pathogenic	0.608
BRCA1	P38398-1.2	Q1811C	Pathogenic	0.675
BRCA1	P38398-1.2	Q1811D	Neutral	0.388
BRCA1	P38398-1.2	Q1811E	Neutral	0.17
BRCA1	P38398-1.2	Q1811F	Pathogenic	0.637
BRCA1	P38398-1.2	Q1811G	Pathogenic	0.774
BRCA1	P38398-1.2	Q1811H	Neutral	0.294
BRCA1	P38398-1.2	Q1811I	Pathogenic	0.579
BRCA1	P38398-1.2	Q1811K	Neutral	0.295
BRCA1	P38398-1.2	Q1811L	Neutral	0.489
BRCA1	P38398-1.2	Q1811M	Neutral	0.318
BRCA1	P38398-1.2	Q1811N	Neutral	0.362
BRCA1	P38398-1.2	Q1811P	Neutral	0.48
BRCA1	P38398-1.2	Q1811R	Neutral	0.359
BRCA1	P38398-1.2	Q1811S	Neutral	0.487
BRCA1	P38398-1.2	Q1811T	Neutral	0.466
BRCA1	P38398-1.2	Q1811V	Neutral	0.486
BRCA1	P38398-1.2	Q1811W	Pathogenic	0.692
BRCA1	P38398-1.2	Q1811Y	Neutral	0.496
BRCA1	P38398-1.2	P1812A	Pathogenic	0.618
BRCA1	P38398-1.2	P1812C	Pathogenic	0.688
BRCA1	P38398-1.2	P1812D	Neutral	0.493
BRCA1	P38398-1.2	P1812E	Pathogenic	0.593
BRCA1	P38398-1.2	P1812F	Pathogenic	0.886
BRCA1	P38398-1.2	P1812G	Pathogenic	0.78
BRCA1	P38398-1.2	P1812H	Pathogenic	0.722
BRCA1	P38398-1.2	P1812I	Pathogenic	0.809
BRCA1	P38398-1.2	P1812K	Pathogenic	0.72
BRCA1	P38398-1.2	P1812L	Pathogenic	0.809
BRCA1	P38398-1.2	P1812M	Pathogenic	0.748
BRCA1	P38398-1.2	P1812N	Pathogenic	0.611
BRCA1	P38398-1.2	P1812Q	Pathogenic	0.621
BRCA1	P38398-1.2	P1812R	Pathogenic	0.832
BRCA1	P38398-1.2	P1812S	Pathogenic	0.585
BRCA1	P38398-1.2	P1812T	Pathogenic	0.509
BRCA1	P38398-1.2	P1812V	Pathogenic	0.661
BRCA1	P38398-1.2	P1812W	Pathogenic	0.935
BRCA1	P38398-1.2	P1812Y	Pathogenic	0.862
BRCA1	P38398-1.2	D1813A	Neutral	0.185
BRCA1	P38398-1.2	D1813C	Neutral	0.174
BRCA1	P38398-1.2	D1813E	Neutral	0.045
BRCA1	P38398-1.2	D1813F	Neutral	0.331
BRCA1	P38398-1.2	D1813G	Neutral	0.195
BRCA1	P38398-1.2	D1813H	Neutral	0.145
BRCA1	P38398-1.2	D1813I	Neutral	0.279
BRCA1	P38398-1.2	D1813K	Neutral	0.2
BRCA1	P38398-1.2	D1813L	Neutral	0.358
BRCA1	P38398-1.2	D1813M	Neutral	0.281
BRCA1	P38398-1.2	D1813N	Neutral	0.048
BRCA1	P38398-1.2	D1813P	Neutral	0.086
BRCA1	P38398-1.2	D1813Q	Neutral	0.098
BRCA1	P38398-1.2	D1813R	Neutral	0.324
BRCA1	P38398-1.2	D1813S	Neutral	0.088
BRCA1	P38398-1.2	D1813T	Neutral	0.088
BRCA1	P38398-1.2	D1813V	Neutral	0.204
BRCA1	P38398-1.2	D1813W	Pathogenic	0.568
BRCA1	P38398-1.2	D1813Y	Neutral	0.365
BRCA1	P38398-1.2	A1814C	Neutral	0.42
BRCA1	P38398-1.2	A1814D	Pathogenic	0.624
BRCA1	P38398-1.2	A1814E	Pathogenic	0.633
BRCA1	P38398-1.2	A1814F	Pathogenic	0.814
BRCA1	P38398-1.2	A1814G	Neutral	0.422
BRCA1	P38398-1.2	A1814H	Pathogenic	0.755
BRCA1	P38398-1.2	A1814I	Pathogenic	0.704
BRCA1	P38398-1.2	A1814K	Pathogenic	0.753
BRCA1	P38398-1.2	A1814L	Pathogenic	0.705
BRCA1	P38398-1.2	A1814M	Pathogenic	0.707
BRCA1	P38398-1.2	A1814N	Pathogenic	0.651
BRCA1	P38398-1.2	A1814P	Pathogenic	0.534
BRCA1	P38398-1.2	A1814Q	Pathogenic	0.66
BRCA1	P38398-1.2	A1814R	Pathogenic	0.803
BRCA1	P38398-1.2	A1814S	Neutral	0.275
BRCA1	P38398-1.2	A1814T	Neutral	0.461
BRCA1	P38398-1.2	A1814V	Pathogenic	0.523
BRCA1	P38398-1.2	A1814W	Pathogenic	0.921
BRCA1	P38398-1.2	A1814Y	Pathogenic	0.836
BRCA1	P38398-1.2	W1815A	Pathogenic	0.992
BRCA1	P38398-1.2	W1815C	Pathogenic	0.983
BRCA1	P38398-1.2	W1815D	Pathogenic	0.99
BRCA1	P38398-1.2	W1815E	Pathogenic	0.979
BRCA1	P38398-1.2	W1815F	Pathogenic	0.866
BRCA1	P38398-1.2	W1815G	Pathogenic	0.992
BRCA1	P38398-1.2	W1815H	Pathogenic	0.965
BRCA1	P38398-1.2	W1815I	Pathogenic	0.973
BRCA1	P38398-1.2	W1815K	Pathogenic	0.963
BRCA1	P38398-1.2	W1815L	Pathogenic	0.961
BRCA1	P38398-1.2	W1815M	Pathogenic	0.944
BRCA1	P38398-1.2	W1815N	Pathogenic	0.989
BRCA1	P38398-1.2	W1815P	Pathogenic	0.991
BRCA1	P38398-1.2	W1815Q	Pathogenic	0.967
BRCA1	P38398-1.2	W1815R	Pathogenic	0.952
BRCA1	P38398-1.2	W1815S	Pathogenic	0.991
BRCA1	P38398-1.2	W1815T	Pathogenic	0.979
BRCA1	P38398-1.2	W1815V	Pathogenic	0.982
BRCA1	P38398-1.2	W1815Y	Pathogenic	0.795
BRCA1	P38398-1.2	T1816A	Neutral	0.1
BRCA1	P38398-1.2	T1816C	Neutral	0.094
BRCA1	P38398-1.2	T1816D	Neutral	0.085
BRCA1	P38398-1.2	T1816E	Neutral	0.112
BRCA1	P38398-1.2	T1816F	Neutral	0.243
BRCA1	P38398-1.2	T1816G	Neutral	0.26
BRCA1	P38398-1.2	T1816H	Neutral	0.184
BRCA1	P38398-1.2	T1816I	Neutral	0.149
BRCA1	P38398-1.2	T1816K	Neutral	0.183
BRCA1	P38398-1.2	T1816L	Neutral	0.149
BRCA1	P38398-1.2	T1816M	Neutral	0.15
BRCA1	P38398-1.2	T1816N	Neutral	0.062
BRCA1	P38398-1.2	T1816P	Neutral	0.087
BRCA1	P38398-1.2	T1816Q	Neutral	0.125
BRCA1	P38398-1.2	T1816R	Neutral	0.23
BRCA1	P38398-1.2	T1816S	Neutral	0.063
BRCA1	P38398-1.2	T1816V	Neutral	0.074
BRCA1	P38398-1.2	T1816W	Neutral	0.372
BRCA1	P38398-1.2	T1816Y	Neutral	0.271
BRCA1	P38398-1.2	E1817A	Neutral	0.241
BRCA1	P38398-1.2	E1817C	Neutral	0.38
BRCA1	P38398-1.2	E1817D	Neutral	0.06
BRCA1	P38398-1.2	E1817F	Neutral	0.31
BRCA1	P38398-1.2	E1817G	Neutral	0.412
BRCA1	P38398-1.2	E1817H	Neutral	0.096
BRCA1	P38398-1.2	E1817I	Neutral	0.26
BRCA1	P38398-1.2	E1817K	Neutral	0.098
BRCA1	P38398-1.2	E1817L	Neutral	0.26
BRCA1	P38398-1.2	E1817M	Neutral	0.198
BRCA1	P38398-1.2	E1817N	Neutral	0.106
BRCA1	P38398-1.2	E1817P	Neutral	0.159
BRCA1	P38398-1.2	E1817Q	Neutral	0.045
BRCA1	P38398-1.2	E1817R	Neutral	0.173
BRCA1	P38398-1.2	E1817S	Neutral	0.163
BRCA1	P38398-1.2	E1817T	Neutral	0.152
BRCA1	P38398-1.2	E1817V	Neutral	0.162
BRCA1	P38398-1.2	E1817W	Neutral	0.453
BRCA1	P38398-1.2	E1817Y	Neutral	0.266
BRCA1	P38398-1.2	D1818A	Neutral	0.429
BRCA1	P38398-1.2	D1818C	Neutral	0.411
BRCA1	P38398-1.2	D1818E	Neutral	0.135
BRCA1	P38398-1.2	D1818F	Pathogenic	0.621
BRCA1	P38398-1.2	D1818G	Neutral	0.444
BRCA1	P38398-1.2	D1818H	Neutral	0.359
BRCA1	P38398-1.2	D1818I	Pathogenic	0.562
BRCA1	P38398-1.2	D1818K	Neutral	0.453
BRCA1	P38398-1.2	D1818L	Pathogenic	0.649
BRCA1	P38398-1.2	D1818M	Pathogenic	0.564
BRCA1	P38398-1.2	D1818N	Neutral	0.144
BRCA1	P38398-1.2	D1818P	Neutral	0.237
BRCA1	P38398-1.2	D1818Q	Neutral	0.264
BRCA1	P38398-1.2	D1818R	Pathogenic	0.614
BRCA1	P38398-1.2	D1818S	Neutral	0.242
BRCA1	P38398-1.2	D1818T	Neutral	0.243
BRCA1	P38398-1.2	D1818V	Neutral	0.459
BRCA1	P38398-1.2	D1818W	Pathogenic	0.813
BRCA1	P38398-1.2	D1818Y	Pathogenic	0.655
BRCA1	P38398-1.2	N1819A	Neutral	0.013
BRCA1	P38398-1.2	N1819C	Neutral	0.012
BRCA1	P38398-1.2	N1819D	Neutral	0.003
BRCA1	P38398-1.2	N1819E	Neutral	0.004
BRCA1	P38398-1.2	N1819F	Neutral	0.022
BRCA1	P38398-1.2	N1819G	Neutral	0.01
BRCA1	P38398-1.2	N1819H	Neutral	0.004
BRCA1	P38398-1.2	N1819I	Neutral	0.018
BRCA1	P38398-1.2	N1819K	Neutral	0.008
BRCA1	P38398-1.2	N1819L	Neutral	0.018
BRCA1	P38398-1.2	N1819M	Neutral	0.012
BRCA1	P38398-1.2	N1819P	Neutral	0.008
BRCA1	P38398-1.2	N1819Q	Neutral	0.005
BRCA1	P38398-1.2	N1819R	Neutral	0.01
BRCA1	P38398-1.2	N1819S	Neutral	0.004
BRCA1	P38398-1.2	N1819T	Neutral	0.004
BRCA1	P38398-1.2	N1819V	Neutral	0.012
BRCA1	P38398-1.2	N1819W	Neutral	0.057
BRCA1	P38398-1.2	N1819Y	Neutral	0.018
BRCA1	P38398-1.2	G1820A	Neutral	0.077
BRCA1	P38398-1.2	G1820C	Neutral	0.271
BRCA1	P38398-1.2	G1820D	Neutral	0.168
BRCA1	P38398-1.2	G1820E	Neutral	0.303
BRCA1	P38398-1.2	G1820F	Pathogenic	0.521
BRCA1	P38398-1.2	G1820H	Neutral	0.349
BRCA1	P38398-1.2	G1820I	Pathogenic	0.551
BRCA1	P38398-1.2	G1820K	Neutral	0.434
BRCA1	P38398-1.2	G1820L	Pathogenic	0.551
BRCA1	P38398-1.2	G1820M	Neutral	0.463
BRCA1	P38398-1.2	G1820N	Neutral	0.136
BRCA1	P38398-1.2	G1820P	Neutral	0.221
BRCA1	P38398-1.2	G1820Q	Neutral	0.328
BRCA1	P38398-1.2	G1820R	Pathogenic	0.506
BRCA1	P38398-1.2	G1820S	Neutral	0.087
BRCA1	P38398-1.2	G1820T	Neutral	0.235
BRCA1	P38398-1.2	G1820V	Neutral	0.361
BRCA1	P38398-1.2	G1820W	Pathogenic	0.583
BRCA1	P38398-1.2	G1820Y	Pathogenic	0.558
BRCA1	P38398-1.2	F1821A	Pathogenic	0.657
BRCA1	P38398-1.2	F1821C	Pathogenic	0.56
BRCA1	P38398-1.2	F1821D	Pathogenic	0.613
BRCA1	P38398-1.2	F1821E	Pathogenic	0.516
BRCA1	P38398-1.2	F1821G	Pathogenic	0.807
BRCA1	P38398-1.2	F1821H	Neutral	0.3
BRCA1	P38398-1.2	F1821I	Neutral	0.212
BRCA1	P38398-1.2	F1821K	Neutral	0.373
BRCA1	P38398-1.2	F1821L	Neutral	0.211
BRCA1	P38398-1.2	F1821M	Neutral	0.21
BRCA1	P38398-1.2	F1821N	Pathogenic	0.587
BRCA1	P38398-1.2	F1821P	Pathogenic	0.706
BRCA1	P38398-1.2	F1821Q	Neutral	0.49
BRCA1	P38398-1.2	F1821R	Neutral	0.442
BRCA1	P38398-1.2	F1821S	Pathogenic	0.625
BRCA1	P38398-1.2	F1821T	Pathogenic	0.518
BRCA1	P38398-1.2	F1821V	Neutral	0.368
BRCA1	P38398-1.2	F1821W	Neutral	0.212
BRCA1	P38398-1.2	F1821Y	Neutral	0.074
BRCA1	P38398-1.2	H1822A	Neutral	0.082
BRCA1	P38398-1.2	H1822C	Neutral	0.077
BRCA1	P38398-1.2	H1822D	Neutral	0.035
BRCA1	P38398-1.2	H1822E	Neutral	0.016
BRCA1	P38398-1.2	H1822F	Neutral	0.028
BRCA1	P38398-1.2	H1822G	Neutral	0.12
BRCA1	P38398-1.2	H1822I	Neutral	0.044
BRCA1	P38398-1.2	H1822K	Neutral	0.028
BRCA1	P38398-1.2	H1822L	Neutral	0.044
BRCA1	P38398-1.2	H1822M	Neutral	0.031
BRCA1	P38398-1.2	H1822N	Neutral	0.015
BRCA1	P38398-1.2	H1822P	Neutral	0.05
BRCA1	P38398-1.2	H1822Q	Neutral	0.015
BRCA1	P38398-1.2	H1822R	Neutral	0.026
BRCA1	P38398-1.2	H1822S	Neutral	0.051
BRCA1	P38398-1.2	H1822T	Neutral	0.048
BRCA1	P38398-1.2	H1822V	Neutral	0.051
BRCA1	P38398-1.2	H1822W	Neutral	0.07
BRCA1	P38398-1.2	H1822Y	Neutral	0.011
BRCA1	P38398-1.2	A1823C	Neutral	0.014
BRCA1	P38398-1.2	A1823D	Neutral	0.031
BRCA1	P38398-1.2	A1823E	Neutral	0.032
BRCA1	P38398-1.2	A1823F	Neutral	0.078
BRCA1	P38398-1.2	A1823G	Neutral	0.014
BRCA1	P38398-1.2	A1823H	Neutral	0.056
BRCA1	P38398-1.2	A1823I	Neutral	0.044
BRCA1	P38398-1.2	A1823K	Neutral	0.056
BRCA1	P38398-1.2	A1823L	Neutral	0.044
BRCA1	P38398-1.2	A1823M	Neutral	0.045
BRCA1	P38398-1.2	A1823N	Neutral	0.035
BRCA1	P38398-1.2	A1823P	Neutral	0.022
BRCA1	P38398-1.2	A1823Q	Neutral	0.036
BRCA1	P38398-1.2	A1823R	Neutral	0.073
BRCA1	P38398-1.2	A1823S	Neutral	0.007
BRCA1	P38398-1.2	A1823T	Neutral	0.016
BRCA1	P38398-1.2	A1823V	Neutral	0.021
BRCA1	P38398-1.2	A1823W	Neutral	0.184
BRCA1	P38398-1.2	A1823Y	Neutral	0.09
BRCA1	P38398-1.2	I1824A	Neutral	0.273
BRCA1	P38398-1.2	I1824C	Neutral	0.2
BRCA1	P38398-1.2	I1824D	Neutral	0.309
BRCA1	P38398-1.2	I1824E	Neutral	0.231
BRCA1	P38398-1.2	I1824F	Neutral	0.088
BRCA1	P38398-1.2	I1824G	Pathogenic	0.629
BRCA1	P38398-1.2	I1824H	Neutral	0.2
BRCA1	P38398-1.2	I1824K	Neutral	0.214
BRCA1	P38398-1.2	I1824L	Neutral	0.035
BRCA1	P38398-1.2	I1824M	Neutral	0.049
BRCA1	P38398-1.2	I1824N	Neutral	0.286
BRCA1	P38398-1.2	I1824P	Neutral	0.32
BRCA1	P38398-1.2	I1824Q	Neutral	0.213
BRCA1	P38398-1.2	I1824R	Neutral	0.267
BRCA1	P38398-1.2	I1824S	Neutral	0.32
BRCA1	P38398-1.2	I1824T	Neutral	0.174
BRCA1	P38398-1.2	I1824V	Neutral	0.037
BRCA1	P38398-1.2	I1824W	Neutral	0.347
BRCA1	P38398-1.2	I1824Y	Neutral	0.135
BRCA1	P38398-1.2	G1825A	Neutral	0.13
BRCA1	P38398-1.2	G1825C	Neutral	0.401
BRCA1	P38398-1.2	G1825D	Neutral	0.266
BRCA1	P38398-1.2	G1825E	Neutral	0.439
BRCA1	P38398-1.2	G1825F	Pathogenic	0.662
BRCA1	P38398-1.2	G1825H	Neutral	0.491
BRCA1	P38398-1.2	G1825I	Pathogenic	0.688
BRCA1	P38398-1.2	G1825K	Pathogenic	0.58
BRCA1	P38398-1.2	G1825L	Pathogenic	0.689
BRCA1	P38398-1.2	G1825M	Pathogenic	0.608
BRCA1	P38398-1.2	G1825N	Neutral	0.22
BRCA1	P38398-1.2	G1825P	Neutral	0.338
BRCA1	P38398-1.2	G1825Q	Neutral	0.468
BRCA1	P38398-1.2	G1825R	Pathogenic	0.648
BRCA1	P38398-1.2	G1825S	Neutral	0.146
BRCA1	P38398-1.2	G1825T	Neutral	0.355
BRCA1	P38398-1.2	G1825V	Pathogenic	0.504
BRCA1	P38398-1.2	G1825W	Pathogenic	0.715
BRCA1	P38398-1.2	G1825Y	Pathogenic	0.695
BRCA1	P38398-1.2	Q1826A	Neutral	0.385
BRCA1	P38398-1.2	Q1826C	Neutral	0.456
BRCA1	P38398-1.2	Q1826D	Neutral	0.203
BRCA1	P38398-1.2	Q1826E	Neutral	0.076
BRCA1	P38398-1.2	Q1826F	Neutral	0.414
BRCA1	P38398-1.2	Q1826G	Pathogenic	0.58
BRCA1	P38398-1.2	Q1826H	Neutral	0.144
BRCA1	P38398-1.2	Q1826I	Neutral	0.356
BRCA1	P38398-1.2	Q1826K	Neutral	0.144
BRCA1	P38398-1.2	Q1826L	Neutral	0.278
BRCA1	P38398-1.2	Q1826M	Neutral	0.158
BRCA1	P38398-1.2	Q1826N	Neutral	0.186
BRCA1	P38398-1.2	Q1826P	Neutral	0.271
BRCA1	P38398-1.2	Q1826R	Neutral	0.184
BRCA1	P38398-1.2	Q1826S	Neutral	0.277
BRCA1	P38398-1.2	Q1826T	Neutral	0.26
BRCA1	P38398-1.2	Q1826V	Neutral	0.276
BRCA1	P38398-1.2	Q1826W	Neutral	0.476
BRCA1	P38398-1.2	Q1826Y	Neutral	0.284
BRCA1	P38398-1.2	M1827A	Neutral	0.183
BRCA1	P38398-1.2	M1827C	Neutral	0.129
BRCA1	P38398-1.2	M1827D	Neutral	0.21
BRCA1	P38398-1.2	M1827E	Neutral	0.111
BRCA1	P38398-1.2	M1827F	Neutral	0.053
BRCA1	P38398-1.2	M1827G	Neutral	0.412
BRCA1	P38398-1.2	M1827H	Neutral	0.094
BRCA1	P38398-1.2	M1827I	Neutral	0.03
BRCA1	P38398-1.2	M1827K	Neutral	0.073
BRCA1	P38398-1.2	M1827L	Neutral	0.021
BRCA1	P38398-1.2	M1827N	Neutral	0.142
BRCA1	P38398-1.2	M1827P	Neutral	0.163
BRCA1	P38398-1.2	M1827Q	Neutral	0.051
BRCA1	P38398-1.2	M1827R	Neutral	0.095
BRCA1	P38398-1.2	M1827S	Neutral	0.163
BRCA1	P38398-1.2	M1827T	Neutral	0.111
BRCA1	P38398-1.2	M1827V	Neutral	0.045
BRCA1	P38398-1.2	M1827W	Neutral	0.13
BRCA1	P38398-1.2	M1827Y	Neutral	0.085
BRCA1	P38398-1.2	C1828A	Pathogenic	0.655
BRCA1	P38398-1.2	C1828D	Pathogenic	0.803
BRCA1	P38398-1.2	C1828E	Pathogenic	0.897
BRCA1	P38398-1.2	C1828F	Pathogenic	0.884
BRCA1	P38398-1.2	C1828G	Pathogenic	0.896
BRCA1	P38398-1.2	C1828H	Pathogenic	0.883
BRCA1	P38398-1.2	C1828I	Pathogenic	0.806
BRCA1	P38398-1.2	C1828K	Pathogenic	0.915
BRCA1	P38398-1.2	C1828L	Pathogenic	0.806
BRCA1	P38398-1.2	C1828M	Pathogenic	0.808
BRCA1	P38398-1.2	C1828N	Pathogenic	0.82
BRCA1	P38398-1.2	C1828P	Pathogenic	0.804
BRCA1	P38398-1.2	C1828Q	Pathogenic	0.873
BRCA1	P38398-1.2	C1828R	Pathogenic	0.935
BRCA1	P38398-1.2	C1828S	Pathogenic	0.704
BRCA1	P38398-1.2	C1828T	Pathogenic	0.677
BRCA1	P38398-1.2	C1828V	Pathogenic	0.734
BRCA1	P38398-1.2	C1828W	Pathogenic	0.934
BRCA1	P38398-1.2	C1828Y	Pathogenic	0.899
BRCA1	P38398-1.2	E1829A	Neutral	0.032
BRCA1	P38398-1.2	E1829C	Neutral	0.059
BRCA1	P38398-1.2	E1829D	Neutral	0.007
BRCA1	P38398-1.2	E1829F	Neutral	0.044
BRCA1	P38398-1.2	E1829G	Neutral	0.067
BRCA1	P38398-1.2	E1829H	Neutral	0.011
BRCA1	P38398-1.2	E1829I	Neutral	0.035
BRCA1	P38398-1.2	E1829K	Neutral	0.011
BRCA1	P38398-1.2	E1829L	Neutral	0.035
BRCA1	P38398-1.2	E1829M	Neutral	0.025
BRCA1	P38398-1.2	E1829N	Neutral	0.012
BRCA1	P38398-1.2	E1829P	Neutral	0.019
BRCA1	P38398-1.2	E1829Q	Neutral	0.005
BRCA1	P38398-1.2	E1829R	Neutral	0.021
BRCA1	P38398-1.2	E1829S	Neutral	0.02
BRCA1	P38398-1.2	E1829T	Neutral	0.018
BRCA1	P38398-1.2	E1829V	Neutral	0.02
BRCA1	P38398-1.2	E1829W	Neutral	0.079
BRCA1	P38398-1.2	E1829Y	Neutral	0.036
BRCA1	P38398-1.2	A1830C	Neutral	0.051
BRCA1	P38398-1.2	A1830D	Neutral	0.11
BRCA1	P38398-1.2	A1830E	Neutral	0.113
BRCA1	P38398-1.2	A1830F	Neutral	0.245
BRCA1	P38398-1.2	A1830G	Neutral	0.051
BRCA1	P38398-1.2	A1830H	Neutral	0.186
BRCA1	P38398-1.2	A1830I	Neutral	0.15
BRCA1	P38398-1.2	A1830K	Neutral	0.185
BRCA1	P38398-1.2	A1830L	Neutral	0.15
BRCA1	P38398-1.2	A1830M	Neutral	0.152
BRCA1	P38398-1.2	A1830N	Neutral	0.121
BRCA1	P38398-1.2	A1830P	Neutral	0.078
BRCA1	P38398-1.2	A1830Q	Neutral	0.126
BRCA1	P38398-1.2	A1830R	Neutral	0.232
BRCA1	P38398-1.2	A1830S	Neutral	0.027
BRCA1	P38398-1.2	A1830T	Neutral	0.06
BRCA1	P38398-1.2	A1830V	Neutral	0.075
BRCA1	P38398-1.2	A1830W	Neutral	0.463
BRCA1	P38398-1.2	A1830Y	Neutral	0.274
BRCA1	P38398-1.2	P1831A	Neutral	0.107
BRCA1	P38398-1.2	P1831C	Neutral	0.141
BRCA1	P38398-1.2	P1831D	Neutral	0.067
BRCA1	P38398-1.2	P1831E	Neutral	0.097
BRCA1	P38398-1.2	P1831F	Neutral	0.366
BRCA1	P38398-1.2	P1831G	Neutral	0.208
BRCA1	P38398-1.2	P1831H	Neutral	0.161
BRCA1	P38398-1.2	P1831I	Neutral	0.239
BRCA1	P38398-1.2	P1831K	Neutral	0.16
BRCA1	P38398-1.2	P1831L	Neutral	0.239
BRCA1	P38398-1.2	P1831M	Neutral	0.18
BRCA1	P38398-1.2	P1831N	Neutral	0.104
BRCA1	P38398-1.2	P1831Q	Neutral	0.108
BRCA1	P38398-1.2	P1831R	Neutral	0.268
BRCA1	P38398-1.2	P1831S	Neutral	0.095
BRCA1	P38398-1.2	P1831T	Neutral	0.071
BRCA1	P38398-1.2	P1831V	Neutral	0.126
BRCA1	P38398-1.2	P1831W	Pathogenic	0.515
BRCA1	P38398-1.2	P1831Y	Neutral	0.317
BRCA1	P38398-1.2	V1832A	Neutral	0.129
BRCA1	P38398-1.2	V1832C	Neutral	0.124
BRCA1	P38398-1.2	V1832D	Neutral	0.202
BRCA1	P38398-1.2	V1832E	Neutral	0.124
BRCA1	P38398-1.2	V1832F	Neutral	0.152
BRCA1	P38398-1.2	V1832G	Neutral	0.4
BRCA1	P38398-1.2	V1832H	Neutral	0.201
BRCA1	P38398-1.2	V1832I	Neutral	0.032
BRCA1	P38398-1.2	V1832K	Neutral	0.2
BRCA1	P38398-1.2	V1832L	Neutral	0.063
BRCA1	P38398-1.2	V1832M	Neutral	0.064
BRCA1	P38398-1.2	V1832N	Neutral	0.185
BRCA1	P38398-1.2	V1832P	Neutral	0.156
BRCA1	P38398-1.2	V1832Q	Neutral	0.137
BRCA1	P38398-1.2	V1832R	Neutral	0.324
BRCA1	P38398-1.2	V1832S	Neutral	0.21
BRCA1	P38398-1.2	V1832T	Neutral	0.076
BRCA1	P38398-1.2	V1832W	Neutral	0.406
BRCA1	P38398-1.2	V1832Y	Neutral	0.171
BRCA1	P38398-1.2	V1833A	Neutral	0.434
BRCA1	P38398-1.2	V1833C	Neutral	0.423
BRCA1	P38398-1.2	V1833D	Pathogenic	0.568
BRCA1	P38398-1.2	V1833E	Neutral	0.423
BRCA1	P38398-1.2	V1833F	Neutral	0.482
BRCA1	P38398-1.2	V1833G	Pathogenic	0.776
BRCA1	P38398-1.2	V1833H	Pathogenic	0.567
BRCA1	P38398-1.2	V1833I	Neutral	0.145
BRCA1	P38398-1.2	V1833K	Pathogenic	0.565
BRCA1	P38398-1.2	V1833L	Neutral	0.261
BRCA1	P38398-1.2	V1833M	Neutral	0.263
BRCA1	P38398-1.2	V1833N	Pathogenic	0.542
BRCA1	P38398-1.2	V1833P	Neutral	0.49
BRCA1	P38398-1.2	V1833Q	Neutral	0.453
BRCA1	P38398-1.2	V1833R	Pathogenic	0.714
BRCA1	P38398-1.2	V1833S	Pathogenic	0.58
BRCA1	P38398-1.2	V1833T	Neutral	0.301
BRCA1	P38398-1.2	V1833W	Pathogenic	0.781
BRCA1	P38398-1.2	V1833Y	Pathogenic	0.517
BRCA1	P38398-1.2	T1834A	Neutral	0.122
BRCA1	P38398-1.2	T1834C	Neutral	0.115
BRCA1	P38398-1.2	T1834D	Neutral	0.103
BRCA1	P38398-1.2	T1834E	Neutral	0.136
BRCA1	P38398-1.2	T1834F	Neutral	0.285
BRCA1	P38398-1.2	T1834G	Neutral	0.304
BRCA1	P38398-1.2	T1834H	Neutral	0.22
BRCA1	P38398-1.2	T1834I	Neutral	0.179
BRCA1	P38398-1.2	T1834K	Neutral	0.218
BRCA1	P38398-1.2	T1834L	Neutral	0.179
BRCA1	P38398-1.2	T1834M	Neutral	0.18
BRCA1	P38398-1.2	T1834N	Neutral	0.076
BRCA1	P38398-1.2	T1834P	Neutral	0.106
BRCA1	P38398-1.2	T1834Q	Neutral	0.151
BRCA1	P38398-1.2	T1834R	Neutral	0.271
BRCA1	P38398-1.2	T1834S	Neutral	0.078
BRCA1	P38398-1.2	T1834V	Neutral	0.091
BRCA1	P38398-1.2	T1834W	Neutral	0.424
BRCA1	P38398-1.2	T1834Y	Neutral	0.317
BRCA1	P38398-1.2	R1835A	Pathogenic	0.502
BRCA1	P38398-1.2	R1835C	Pathogenic	0.574
BRCA1	P38398-1.2	R1835D	Neutral	0.465
BRCA1	P38398-1.2	R1835E	Neutral	0.219
BRCA1	P38398-1.2	R1835F	Neutral	0.309
BRCA1	P38398-1.2	R1835G	Pathogenic	0.69
BRCA1	P38398-1.2	R1835H	Neutral	0.184
BRCA1	P38398-1.2	R1835I	Neutral	0.363
BRCA1	P38398-1.2	R1835K	Neutral	0.071
BRCA1	P38398-1.2	R1835L	Neutral	0.284
BRCA1	P38398-1.2	R1835M	Neutral	0.218
BRCA1	P38398-1.2	R1835N	Neutral	0.272
BRCA1	P38398-1.2	R1835P	Neutral	0.463
BRCA1	P38398-1.2	R1835Q	Neutral	0.147
BRCA1	P38398-1.2	R1835S	Neutral	0.47
BRCA1	P38398-1.2	R1835T	Neutral	0.361
BRCA1	P38398-1.2	R1835V	Neutral	0.468
BRCA1	P38398-1.2	R1835W	Neutral	0.317
BRCA1	P38398-1.2	R1835Y	Neutral	0.217
BRCA1	P38398-1.2	E1836A	Neutral	0.092
BRCA1	P38398-1.2	E1836C	Neutral	0.164
BRCA1	P38398-1.2	E1836D	Neutral	0.02
BRCA1	P38398-1.2	E1836F	Neutral	0.125
BRCA1	P38398-1.2	E1836G	Neutral	0.183
BRCA1	P38398-1.2	E1836H	Neutral	0.033
BRCA1	P38398-1.2	E1836I	Neutral	0.101
BRCA1	P38398-1.2	E1836K	Neutral	0.034
BRCA1	P38398-1.2	E1836L	Neutral	0.101
BRCA1	P38398-1.2	E1836M	Neutral	0.073
BRCA1	P38398-1.2	E1836N	Neutral	0.036
BRCA1	P38398-1.2	E1836P	Neutral	0.057
BRCA1	P38398-1.2	E1836Q	Neutral	0.015
BRCA1	P38398-1.2	E1836R	Neutral	0.063
BRCA1	P38398-1.2	E1836S	Neutral	0.058
BRCA1	P38398-1.2	E1836T	Neutral	0.054
BRCA1	P38398-1.2	E1836V	Neutral	0.058
BRCA1	P38398-1.2	E1836W	Neutral	0.209
BRCA1	P38398-1.2	E1836Y	Neutral	0.104
BRCA1	P38398-1.2	W1837A	Pathogenic	0.99
BRCA1	P38398-1.2	W1837C	Pathogenic	0.978
BRCA1	P38398-1.2	W1837D	Pathogenic	0.988
BRCA1	P38398-1.2	W1837E	Pathogenic	0.974
BRCA1	P38398-1.2	W1837F	Pathogenic	0.838
BRCA1	P38398-1.2	W1837G	Pathogenic	0.99
BRCA1	P38398-1.2	W1837H	Pathogenic	0.956
BRCA1	P38398-1.2	W1837I	Pathogenic	0.966
BRCA1	P38398-1.2	W1837K	Pathogenic	0.955
BRCA1	P38398-1.2	W1837L	Pathogenic	0.952
BRCA1	P38398-1.2	W1837M	Pathogenic	0.931
BRCA1	P38398-1.2	W1837N	Pathogenic	0.986
BRCA1	P38398-1.2	W1837P	Pathogenic	0.988
BRCA1	P38398-1.2	W1837Q	Pathogenic	0.96
BRCA1	P38398-1.2	W1837R	Pathogenic	0.94
BRCA1	P38398-1.2	W1837S	Pathogenic	0.988
BRCA1	P38398-1.2	W1837T	Pathogenic	0.974
BRCA1	P38398-1.2	W1837V	Pathogenic	0.977
BRCA1	P38398-1.2	W1837Y	Pathogenic	0.756
BRCA1	P38398-1.2	V1838A	Pathogenic	0.587
BRCA1	P38398-1.2	V1838C	Pathogenic	0.576
BRCA1	P38398-1.2	V1838D	Pathogenic	0.709
BRCA1	P38398-1.2	V1838E	Pathogenic	0.576
BRCA1	P38398-1.2	V1838F	Pathogenic	0.633
BRCA1	P38398-1.2	V1838G	Pathogenic	0.865
BRCA1	P38398-1.2	V1838H	Pathogenic	0.708
BRCA1	P38398-1.2	V1838I	Neutral	0.24
BRCA1	P38398-1.2	V1838K	Pathogenic	0.706
BRCA1	P38398-1.2	V1838L	Neutral	0.395
BRCA1	P38398-1.2	V1838M	Neutral	0.397
BRCA1	P38398-1.2	V1838N	Pathogenic	0.686
BRCA1	P38398-1.2	V1838P	Pathogenic	0.641
BRCA1	P38398-1.2	V1838Q	Pathogenic	0.605
BRCA1	P38398-1.2	V1838R	Pathogenic	0.822
BRCA1	P38398-1.2	V1838S	Pathogenic	0.719
BRCA1	P38398-1.2	V1838T	Neutral	0.444
BRCA1	P38398-1.2	V1838W	Pathogenic	0.868
BRCA1	P38398-1.2	V1838Y	Pathogenic	0.665
BRCA1	P38398-1.2	L1839A	Pathogenic	0.747
BRCA1	P38398-1.2	L1839C	Pathogenic	0.662
BRCA1	P38398-1.2	L1839D	Pathogenic	0.835
BRCA1	P38398-1.2	L1839E	Pathogenic	0.703
BRCA1	P38398-1.2	L1839F	Neutral	0.431
BRCA1	P38398-1.2	L1839G	Pathogenic	0.93
BRCA1	P38398-1.2	L1839H	Pathogenic	0.663
BRCA1	P38398-1.2	L1839I	Neutral	0.223
BRCA1	P38398-1.2	L1839K	Pathogenic	0.599
BRCA1	P38398-1.2	L1839M	Neutral	0.221
BRCA1	P38398-1.2	L1839N	Pathogenic	0.759
BRCA1	P38398-1.2	L1839P	Pathogenic	0.787
BRCA1	P38398-1.2	L1839Q	Pathogenic	0.597
BRCA1	P38398-1.2	L1839R	Pathogenic	0.666
BRCA1	P38398-1.2	L1839S	Pathogenic	0.787
BRCA1	P38398-1.2	L1839T	Pathogenic	0.624
BRCA1	P38398-1.2	L1839V	Neutral	0.384
BRCA1	P38398-1.2	L1839W	Pathogenic	0.743
BRCA1	P38398-1.2	L1839Y	Pathogenic	0.552
BRCA1	P38398-1.2	D1840A	Pathogenic	0.734
BRCA1	P38398-1.2	D1840C	Pathogenic	0.72
BRCA1	P38398-1.2	D1840E	Neutral	0.364
BRCA1	P38398-1.2	D1840F	Pathogenic	0.857
BRCA1	P38398-1.2	D1840G	Pathogenic	0.746
BRCA1	P38398-1.2	D1840H	Pathogenic	0.673
BRCA1	P38398-1.2	D1840I	Pathogenic	0.825
BRCA1	P38398-1.2	D1840K	Pathogenic	0.752
BRCA1	P38398-1.2	D1840L	Pathogenic	0.872
BRCA1	P38398-1.2	D1840M	Pathogenic	0.826
BRCA1	P38398-1.2	D1840N	Neutral	0.382
BRCA1	P38398-1.2	D1840P	Pathogenic	0.533
BRCA1	P38398-1.2	D1840Q	Pathogenic	0.568
BRCA1	P38398-1.2	D1840R	Pathogenic	0.854
BRCA1	P38398-1.2	D1840S	Pathogenic	0.54
BRCA1	P38398-1.2	D1840T	Pathogenic	0.541
BRCA1	P38398-1.2	D1840V	Pathogenic	0.758
BRCA1	P38398-1.2	D1840W	Pathogenic	0.941
BRCA1	P38398-1.2	D1840Y	Pathogenic	0.875
BRCA1	P38398-1.2	S1841A	Neutral	0.277
BRCA1	P38398-1.2	S1841C	Neutral	0.477
BRCA1	P38398-1.2	S1841D	Neutral	0.416
BRCA1	P38398-1.2	S1841E	Pathogenic	0.516
BRCA1	P38398-1.2	S1841F	Pathogenic	0.793
BRCA1	P38398-1.2	S1841G	Neutral	0.458
BRCA1	P38398-1.2	S1841H	Pathogenic	0.654
BRCA1	P38398-1.2	S1841I	Pathogenic	0.751
BRCA1	P38398-1.2	S1841K	Pathogenic	0.654
BRCA1	P38398-1.2	S1841L	Pathogenic	0.751
BRCA1	P38398-1.2	S1841M	Pathogenic	0.679
BRCA1	P38398-1.2	S1841N	Neutral	0.357
BRCA1	P38398-1.2	S1841P	Pathogenic	0.501
BRCA1	P38398-1.2	S1841Q	Pathogenic	0.546
BRCA1	P38398-1.2	S1841R	Pathogenic	0.784
BRCA1	P38398-1.2	S1841T	Neutral	0.343
BRCA1	P38398-1.2	S1841V	Pathogenic	0.666
BRCA1	P38398-1.2	S1841W	Pathogenic	0.911
BRCA1	P38398-1.2	S1841Y	Pathogenic	0.817
BRCA1	P38398-1.2	V1842A	Neutral	0.176
BRCA1	P38398-1.2	V1842C	Neutral	0.17
BRCA1	P38398-1.2	V1842D	Neutral	0.268
BRCA1	P38398-1.2	V1842E	Neutral	0.17
BRCA1	P38398-1.2	V1842F	Neutral	0.206
BRCA1	P38398-1.2	V1842G	Neutral	0.491
BRCA1	P38398-1.2	V1842H	Neutral	0.267
BRCA1	P38398-1.2	V1842I	Neutral	0.045
BRCA1	P38398-1.2	V1842K	Neutral	0.266
BRCA1	P38398-1.2	V1842L	Neutral	0.089
BRCA1	P38398-1.2	V1842M	Neutral	0.09
BRCA1	P38398-1.2	V1842N	Neutral	0.247
BRCA1	P38398-1.2	V1842P	Neutral	0.211
BRCA1	P38398-1.2	V1842Q	Neutral	0.187
BRCA1	P38398-1.2	V1842R	Neutral	0.41
BRCA1	P38398-1.2	V1842S	Neutral	0.278
BRCA1	P38398-1.2	V1842T	Neutral	0.107
BRCA1	P38398-1.2	V1842W	Neutral	0.498
BRCA1	P38398-1.2	V1842Y	Neutral	0.23
BRCA1	P38398-1.2	A1843C	Neutral	0.221
BRCA1	P38398-1.2	A1843D	Neutral	0.394
BRCA1	P38398-1.2	A1843E	Neutral	0.403
BRCA1	P38398-1.2	A1843F	Pathogenic	0.632
BRCA1	P38398-1.2	A1843G	Neutral	0.222
BRCA1	P38398-1.2	A1843H	Pathogenic	0.546
BRCA1	P38398-1.2	A1843I	Neutral	0.483
BRCA1	P38398-1.2	A1843K	Pathogenic	0.544
BRCA1	P38398-1.2	A1843L	Neutral	0.483
BRCA1	P38398-1.2	A1843M	Neutral	0.485
BRCA1	P38398-1.2	A1843N	Neutral	0.422
BRCA1	P38398-1.2	A1843P	Neutral	0.309
BRCA1	P38398-1.2	A1843Q	Neutral	0.432
BRCA1	P38398-1.2	A1843R	Pathogenic	0.615
BRCA1	P38398-1.2	A1843S	Neutral	0.129
BRCA1	P38398-1.2	A1843T	Neutral	0.251
BRCA1	P38398-1.2	A1843V	Neutral	0.301
BRCA1	P38398-1.2	A1843W	Pathogenic	0.82
BRCA1	P38398-1.2	A1843Y	Pathogenic	0.666
BRCA1	P38398-1.2	L1844A	Neutral	0.162
BRCA1	P38398-1.2	L1844C	Neutral	0.114
BRCA1	P38398-1.2	L1844D	Neutral	0.248
BRCA1	P38398-1.2	L1844E	Neutral	0.134
BRCA1	P38398-1.2	L1844F	Neutral	0.047
BRCA1	P38398-1.2	L1844G	Neutral	0.466
BRCA1	P38398-1.2	L1844H	Neutral	0.114
BRCA1	P38398-1.2	L1844I	Neutral	0.018
BRCA1	P38398-1.2	L1844K	Neutral	0.089
BRCA1	P38398-1.2	L1844M	Neutral	0.018
BRCA1	P38398-1.2	L1844N	Neutral	0.171
BRCA1	P38398-1.2	L1844P	Neutral	0.195
BRCA1	P38398-1.2	L1844Q	Neutral	0.088
BRCA1	P38398-1.2	L1844R	Neutral	0.115
BRCA1	P38398-1.2	L1844S	Neutral	0.195
BRCA1	P38398-1.2	L1844T	Neutral	0.098
BRCA1	P38398-1.2	L1844V	Neutral	0.039
BRCA1	P38398-1.2	L1844W	Neutral	0.159
BRCA1	P38398-1.2	L1844Y	Neutral	0.074
BRCA1	P38398-1.2	Y1845A	Pathogenic	0.757
BRCA1	P38398-1.2	Y1845C	Pathogenic	0.674
BRCA1	P38398-1.2	Y1845D	Pathogenic	0.72
BRCA1	P38398-1.2	Y1845E	Pathogenic	0.546
BRCA1	P38398-1.2	Y1845F	Neutral	0.1
BRCA1	P38398-1.2	Y1845G	Pathogenic	0.872
BRCA1	P38398-1.2	Y1845H	Neutral	0.189
BRCA1	P38398-1.2	Y1845I	Neutral	0.378
BRCA1	P38398-1.2	Y1845K	Neutral	0.401
BRCA1	P38398-1.2	Y1845L	Neutral	0.378
BRCA1	P38398-1.2	Y1845M	Neutral	0.38
BRCA1	P38398-1.2	Y1845N	Pathogenic	0.616
BRCA1	P38398-1.2	Y1845P	Pathogenic	0.73
BRCA1	P38398-1.2	Y1845Q	Neutral	0.43
BRCA1	P38398-1.2	Y1845R	Neutral	0.406
BRCA1	P38398-1.2	Y1845S	Pathogenic	0.73
BRCA1	P38398-1.2	Y1845T	Pathogenic	0.635
BRCA1	P38398-1.2	Y1845V	Neutral	0.483
BRCA1	P38398-1.2	Y1845W	Neutral	0.184
BRCA1	P38398-1.2	Q1846A	Neutral	0.185
BRCA1	P38398-1.2	Q1846C	Neutral	0.234
BRCA1	P38398-1.2	Q1846D	Neutral	0.085
BRCA1	P38398-1.2	Q1846E	Neutral	0.029
BRCA1	P38398-1.2	Q1846F	Neutral	0.204
BRCA1	P38398-1.2	Q1846G	Neutral	0.334
BRCA1	P38398-1.2	Q1846H	Neutral	0.057
BRCA1	P38398-1.2	Q1846I	Neutral	0.167
BRCA1	P38398-1.2	Q1846K	Neutral	0.058
BRCA1	P38398-1.2	Q1846L	Neutral	0.123
BRCA1	P38398-1.2	Q1846M	Neutral	0.064
BRCA1	P38398-1.2	Q1846N	Neutral	0.077
BRCA1	P38398-1.2	Q1846P	Neutral	0.119
BRCA1	P38398-1.2	Q1846R	Neutral	0.076
BRCA1	P38398-1.2	Q1846S	Neutral	0.122
BRCA1	P38398-1.2	Q1846T	Neutral	0.113
BRCA1	P38398-1.2	Q1846V	Neutral	0.121
BRCA1	P38398-1.2	Q1846W	Neutral	0.248
BRCA1	P38398-1.2	Q1846Y	Neutral	0.126
BRCA1	P38398-1.2	C1847A	Neutral	0.103
BRCA1	P38398-1.2	C1847D	Neutral	0.197
BRCA1	P38398-1.2	C1847E	Neutral	0.345
BRCA1	P38398-1.2	C1847F	Neutral	0.315
BRCA1	P38398-1.2	C1847G	Neutral	0.341
BRCA1	P38398-1.2	C1847H	Neutral	0.312
BRCA1	P38398-1.2	C1847I	Neutral	0.2
BRCA1	P38398-1.2	C1847K	Neutral	0.393
BRCA1	P38398-1.2	C1847L	Neutral	0.201
BRCA1	P38398-1.2	C1847M	Neutral	0.202
BRCA1	P38398-1.2	C1847N	Neutral	0.215
BRCA1	P38398-1.2	C1847P	Neutral	0.198
BRCA1	P38398-1.2	C1847Q	Neutral	0.292
BRCA1	P38398-1.2	C1847R	Neutral	0.464
BRCA1	P38398-1.2	C1847S	Neutral	0.125
BRCA1	P38398-1.2	C1847T	Neutral	0.112
BRCA1	P38398-1.2	C1847V	Neutral	0.143
BRCA1	P38398-1.2	C1847W	Neutral	0.46
BRCA1	P38398-1.2	C1847Y	Neutral	0.348
BRCA1	P38398-1.2	Q1848A	Neutral	0.446
BRCA1	P38398-1.2	Q1848C	Pathogenic	0.519
BRCA1	P38398-1.2	Q1848D	Neutral	0.247
BRCA1	P38398-1.2	Q1848E	Neutral	0.096
BRCA1	P38398-1.2	Q1848F	Neutral	0.476
BRCA1	P38398-1.2	Q1848G	Pathogenic	0.64
BRCA1	P38398-1.2	Q1848H	Neutral	0.177
BRCA1	P38398-1.2	Q1848I	Neutral	0.416
BRCA1	P38398-1.2	Q1848K	Neutral	0.178
BRCA1	P38398-1.2	Q1848L	Neutral	0.331
BRCA1	P38398-1.2	Q1848M	Neutral	0.194
BRCA1	P38398-1.2	Q1848N	Neutral	0.227
BRCA1	P38398-1.2	Q1848P	Neutral	0.324
BRCA1	P38398-1.2	Q1848R	Neutral	0.224
BRCA1	P38398-1.2	Q1848S	Neutral	0.33
BRCA1	P38398-1.2	Q1848T	Neutral	0.311
BRCA1	P38398-1.2	Q1848V	Neutral	0.328
BRCA1	P38398-1.2	Q1848W	Pathogenic	0.538
BRCA1	P38398-1.2	Q1848Y	Neutral	0.337
BRCA1	P38398-1.2	E1849A	Neutral	0.138
BRCA1	P38398-1.2	E1849C	Neutral	0.236
BRCA1	P38398-1.2	E1849D	Neutral	0.031
BRCA1	P38398-1.2	E1849F	Neutral	0.184
BRCA1	P38398-1.2	E1849G	Neutral	0.261
BRCA1	P38398-1.2	E1849H	Neutral	0.051
BRCA1	P38398-1.2	E1849I	Neutral	0.15
BRCA1	P38398-1.2	E1849K	Neutral	0.052
BRCA1	P38398-1.2	E1849L	Neutral	0.15
BRCA1	P38398-1.2	E1849M	Neutral	0.11
BRCA1	P38398-1.2	E1849N	Neutral	0.056
BRCA1	P38398-1.2	E1849P	Neutral	0.087
BRCA1	P38398-1.2	E1849Q	Neutral	0.023
BRCA1	P38398-1.2	E1849R	Neutral	0.095
BRCA1	P38398-1.2	E1849S	Neutral	0.089
BRCA1	P38398-1.2	E1849T	Neutral	0.082
BRCA1	P38398-1.2	E1849V	Neutral	0.089
BRCA1	P38398-1.2	E1849W	Neutral	0.294
BRCA1	P38398-1.2	E1849Y	Neutral	0.154
BRCA1	P38398-1.2	L1850A	Pathogenic	0.62
BRCA1	P38398-1.2	L1850C	Pathogenic	0.52
BRCA1	P38398-1.2	L1850D	Pathogenic	0.736
BRCA1	P38398-1.2	L1850E	Pathogenic	0.566
BRCA1	P38398-1.2	L1850F	Neutral	0.295
BRCA1	P38398-1.2	L1850G	Pathogenic	0.88
BRCA1	P38398-1.2	L1850H	Pathogenic	0.52
BRCA1	P38398-1.2	L1850I	Neutral	0.137
BRCA1	P38398-1.2	L1850K	Neutral	0.452
BRCA1	P38398-1.2	L1850M	Neutral	0.136
BRCA1	P38398-1.2	L1850N	Pathogenic	0.635
BRCA1	P38398-1.2	L1850P	Pathogenic	0.671
BRCA1	P38398-1.2	L1850Q	Neutral	0.45
BRCA1	P38398-1.2	L1850R	Pathogenic	0.524
BRCA1	P38398-1.2	L1850S	Pathogenic	0.671
BRCA1	P38398-1.2	L1850T	Neutral	0.478
BRCA1	P38398-1.2	L1850V	Neutral	0.256
BRCA1	P38398-1.2	L1850W	Pathogenic	0.615
BRCA1	P38398-1.2	L1850Y	Neutral	0.404
BRCA1	P38398-1.2	D1851A	Neutral	0.101
BRCA1	P38398-1.2	D1851C	Neutral	0.094
BRCA1	P38398-1.2	D1851E	Neutral	0.023
BRCA1	P38398-1.2	D1851F	Neutral	0.196
BRCA1	P38398-1.2	D1851G	Neutral	0.106
BRCA1	P38398-1.2	D1851H	Neutral	0.077
BRCA1	P38398-1.2	D1851I	Neutral	0.16
BRCA1	P38398-1.2	D1851K	Neutral	0.11
BRCA1	P38398-1.2	D1851L	Neutral	0.216
BRCA1	P38398-1.2	D1851M	Neutral	0.162
BRCA1	P38398-1.2	D1851N	Neutral	0.024
BRCA1	P38398-1.2	D1851P	Neutral	0.044
BRCA1	P38398-1.2	D1851Q	Neutral	0.051
BRCA1	P38398-1.2	D1851R	Neutral	0.191
BRCA1	P38398-1.2	D1851S	Neutral	0.045
BRCA1	P38398-1.2	D1851T	Neutral	0.046
BRCA1	P38398-1.2	D1851V	Neutral	0.112
BRCA1	P38398-1.2	D1851W	Neutral	0.393
BRCA1	P38398-1.2	D1851Y	Neutral	0.221
BRCA1	P38398-1.2	T1852A	Neutral	0.042
BRCA1	P38398-1.2	T1852C	Neutral	0.039
BRCA1	P38398-1.2	T1852D	Neutral	0.035
BRCA1	P38398-1.2	T1852E	Neutral	0.047
BRCA1	P38398-1.2	T1852F	Neutral	0.111
BRCA1	P38398-1.2	T1852G	Neutral	0.121
BRCA1	P38398-1.2	T1852H	Neutral	0.081
BRCA1	P38398-1.2	T1852I	Neutral	0.064
BRCA1	P38398-1.2	T1852K	Neutral	0.08
BRCA1	P38398-1.2	T1852L	Neutral	0.064
BRCA1	P38398-1.2	T1852M	Neutral	0.064
BRCA1	P38398-1.2	T1852N	Neutral	0.025
BRCA1	P38398-1.2	T1852P	Neutral	0.036
BRCA1	P38398-1.2	T1852Q	Neutral	0.053
BRCA1	P38398-1.2	T1852R	Neutral	0.105
BRCA1	P38398-1.2	T1852S	Neutral	0.026
BRCA1	P38398-1.2	T1852V	Neutral	0.03
BRCA1	P38398-1.2	T1852W	Neutral	0.188
BRCA1	P38398-1.2	T1852Y	Neutral	0.127
BRCA1	P38398-1.2	Y1853A	Pathogenic	0.926
BRCA1	P38398-1.2	Y1853C	Pathogenic	0.893
BRCA1	P38398-1.2	Y1853D	Pathogenic	0.912
BRCA1	P38398-1.2	Y1853E	Pathogenic	0.829
BRCA1	P38398-1.2	Y1853F	Neutral	0.309
BRCA1	P38398-1.2	Y1853G	Pathogenic	0.965
BRCA1	P38398-1.2	Y1853H	Neutral	0.485
BRCA1	P38398-1.2	Y1853I	Pathogenic	0.71
BRCA1	P38398-1.2	Y1853K	Pathogenic	0.73
BRCA1	P38398-1.2	Y1853L	Pathogenic	0.711
BRCA1	P38398-1.2	Y1853M	Pathogenic	0.713
BRCA1	P38398-1.2	Y1853N	Pathogenic	0.866
BRCA1	P38398-1.2	Y1853P	Pathogenic	0.916
BRCA1	P38398-1.2	Y1853Q	Pathogenic	0.753
BRCA1	P38398-1.2	Y1853R	Pathogenic	0.734
BRCA1	P38398-1.2	Y1853S	Pathogenic	0.916
BRCA1	P38398-1.2	Y1853T	Pathogenic	0.876
BRCA1	P38398-1.2	Y1853V	Pathogenic	0.791
BRCA1	P38398-1.2	Y1853W	Neutral	0.477
BRCA1	P38398-1.2	L1854A	Pathogenic	0.788
BRCA1	P38398-1.2	L1854C	Pathogenic	0.712
BRCA1	P38398-1.2	L1854D	Pathogenic	0.865
BRCA1	P38398-1.2	L1854E	Pathogenic	0.749
BRCA1	P38398-1.2	L1854F	Neutral	0.489
BRCA1	P38398-1.2	L1854G	Pathogenic	0.944
BRCA1	P38398-1.2	L1854H	Pathogenic	0.713
BRCA1	P38398-1.2	L1854I	Neutral	0.265
BRCA1	P38398-1.2	L1854K	Pathogenic	0.653
BRCA1	P38398-1.2	L1854M	Neutral	0.264
BRCA1	P38398-1.2	L1854N	Pathogenic	0.799
BRCA1	P38398-1.2	L1854P	Pathogenic	0.824
BRCA1	P38398-1.2	L1854Q	Pathogenic	0.651
BRCA1	P38398-1.2	L1854R	Pathogenic	0.715
BRCA1	P38398-1.2	L1854S	Pathogenic	0.823
BRCA1	P38398-1.2	L1854T	Pathogenic	0.676
BRCA1	P38398-1.2	L1854V	Neutral	0.441
BRCA1	P38398-1.2	L1854W	Pathogenic	0.785
BRCA1	P38398-1.2	L1854Y	Pathogenic	0.608
BRCA1	P38398-1.2	I1855A	Neutral	0.135
BRCA1	P38398-1.2	I1855C	Neutral	0.094
BRCA1	P38398-1.2	I1855D	Neutral	0.157
BRCA1	P38398-1.2	I1855E	Neutral	0.111
BRCA1	P38398-1.2	I1855F	Neutral	0.039
BRCA1	P38398-1.2	I1855G	Neutral	0.414
BRCA1	P38398-1.2	I1855H	Neutral	0.094
BRCA1	P38398-1.2	I1855K	Neutral	0.102
BRCA1	P38398-1.2	I1855L	Neutral	0.015
BRCA1	P38398-1.2	I1855M	Neutral	0.021
BRCA1	P38398-1.2	I1855N	Neutral	0.143
BRCA1	P38398-1.2	I1855P	Neutral	0.164
BRCA1	P38398-1.2	I1855Q	Neutral	0.101
BRCA1	P38398-1.2	I1855R	Neutral	0.132
BRCA1	P38398-1.2	I1855S	Neutral	0.164
BRCA1	P38398-1.2	I1855T	Neutral	0.081
BRCA1	P38398-1.2	I1855V	Neutral	0.016
BRCA1	P38398-1.2	I1855W	Neutral	0.181
BRCA1	P38398-1.2	I1855Y	Neutral	0.061
BRCA1	P38398-1.2	P1856A	Neutral	0.1
BRCA1	P38398-1.2	P1856C	Neutral	0.131
BRCA1	P38398-1.2	P1856D	Neutral	0.062
BRCA1	P38398-1.2	P1856E	Neutral	0.091
BRCA1	P38398-1.2	P1856F	Neutral	0.347
BRCA1	P38398-1.2	P1856G	Neutral	0.195
BRCA1	P38398-1.2	P1856H	Neutral	0.151
BRCA1	P38398-1.2	P1856I	Neutral	0.224
BRCA1	P38398-1.2	P1856K	Neutral	0.15
BRCA1	P38398-1.2	P1856L	Neutral	0.225
BRCA1	P38398-1.2	P1856M	Neutral	0.169
BRCA1	P38398-1.2	P1856N	Neutral	0.097
BRCA1	P38398-1.2	P1856Q	Neutral	0.101
BRCA1	P38398-1.2	P1856R	Neutral	0.253
BRCA1	P38398-1.2	P1856S	Neutral	0.088
BRCA1	P38398-1.2	P1856T	Neutral	0.066
BRCA1	P38398-1.2	P1856V	Neutral	0.118
BRCA1	P38398-1.2	P1856W	Neutral	0.495
BRCA1	P38398-1.2	P1856Y	Neutral	0.3
BRCA1	P38398-1.2	Q1857A	Neutral	0.074
BRCA1	P38398-1.2	Q1857C	Neutral	0.097
BRCA1	P38398-1.2	Q1857D	Neutral	0.032
BRCA1	P38398-1.2	Q1857E	Neutral	0.01
BRCA1	P38398-1.2	Q1857F	Neutral	0.083
BRCA1	P38398-1.2	Q1857G	Neutral	0.15
BRCA1	P38398-1.2	Q1857H	Neutral	0.021
BRCA1	P38398-1.2	Q1857I	Neutral	0.066
BRCA1	P38398-1.2	Q1857K	Neutral	0.021
BRCA1	P38398-1.2	Q1857L	Neutral	0.047
BRCA1	P38398-1.2	Q1857M	Neutral	0.023
BRCA1	P38398-1.2	Q1857N	Neutral	0.028
BRCA1	P38398-1.2	Q1857P	Neutral	0.045
BRCA1	P38398-1.2	Q1857R	Neutral	0.028
BRCA1	P38398-1.2	Q1857S	Neutral	0.047
BRCA1	P38398-1.2	Q1857T	Neutral	0.043
BRCA1	P38398-1.2	Q1857V	Neutral	0.046
BRCA1	P38398-1.2	Q1857W	Neutral	0.104
BRCA1	P38398-1.2	Q1857Y	Neutral	0.048
BRCA1	P38398-1.2	I1858A	Neutral	0.007
BRCA1	P38398-1.2	I1858C	Neutral	0.005
BRCA1	P38398-1.2	I1858D	Neutral	0.009
BRCA1	P38398-1.2	I1858E	Neutral	0.006
BRCA1	P38398-1.2	I1858F	Neutral	0.002
BRCA1	P38398-1.2	I1858G	Neutral	0.032
BRCA1	P38398-1.2	I1858H	Neutral	0.005
BRCA1	P38398-1.2	I1858K	Neutral	0.005
BRCA1	P38398-1.2	I1858L	Neutral	0.001
BRCA1	P38398-1.2	I1858M	Neutral	0.001
BRCA1	P38398-1.2	I1858N	Neutral	0.008
BRCA1	P38398-1.2	I1858P	Neutral	0.009
BRCA1	P38398-1.2	I1858Q	Neutral	0.005
BRCA1	P38398-1.2	I1858R	Neutral	0.007
BRCA1	P38398-1.2	I1858S	Neutral	0.009
BRCA1	P38398-1.2	I1858T	Neutral	0.004
BRCA1	P38398-1.2	I1858V	Neutral	0.001
BRCA1	P38398-1.2	I1858W	Neutral	0.01
BRCA1	P38398-1.2	I1858Y	Neutral	0.003
BRCA1	P38398-1.2	P1859A	Neutral	0.041
BRCA1	P38398-1.2	P1859C	Neutral	0.056
BRCA1	P38398-1.2	P1859D	Neutral	0.025
BRCA1	P38398-1.2	P1859E	Neutral	0.037
BRCA1	P38398-1.2	P1859F	Neutral	0.172
BRCA1	P38398-1.2	P1859G	Neutral	0.086
BRCA1	P38398-1.2	P1859H	Neutral	0.065
BRCA1	P38398-1.2	P1859I	Neutral	0.101
BRCA1	P38398-1.2	P1859K	Neutral	0.064
BRCA1	P38398-1.2	P1859L	Neutral	0.101
BRCA1	P38398-1.2	P1859M	Neutral	0.073
BRCA1	P38398-1.2	P1859N	Neutral	0.04
BRCA1	P38398-1.2	P1859Q	Neutral	0.042
BRCA1	P38398-1.2	P1859R	Neutral	0.116
BRCA1	P38398-1.2	P1859S	Neutral	0.036
BRCA1	P38398-1.2	P1859T	Neutral	0.027
BRCA1	P38398-1.2	P1859V	Neutral	0.049
BRCA1	P38398-1.2	P1859W	Neutral	0.277
BRCA1	P38398-1.2	P1859Y	Neutral	0.143
BRCA1	P38398-1.2	H1860A	Neutral	0.014
BRCA1	P38398-1.2	H1860C	Neutral	0.013
BRCA1	P38398-1.2	H1860D	Neutral	0.006
BRCA1	P38398-1.2	H1860E	Neutral	0.003
BRCA1	P38398-1.2	H1860F	Neutral	0.004
BRCA1	P38398-1.2	H1860G	Neutral	0.021
BRCA1	P38398-1.2	H1860I	Neutral	0.007
BRCA1	P38398-1.2	H1860K	Neutral	0.004
BRCA1	P38398-1.2	H1860L	Neutral	0.007
BRCA1	P38398-1.2	H1860M	Neutral	0.005
BRCA1	P38398-1.2	H1860N	Neutral	0.002
BRCA1	P38398-1.2	H1860P	Neutral	0.008
BRCA1	P38398-1.2	H1860Q	Neutral	0.002
BRCA1	P38398-1.2	H1860R	Neutral	0.004
BRCA1	P38398-1.2	H1860S	Neutral	0.008
BRCA1	P38398-1.2	H1860T	Neutral	0.008
BRCA1	P38398-1.2	H1860V	Neutral	0.008
BRCA1	P38398-1.2	H1860W	Neutral	0.012
BRCA1	P38398-1.2	H1860Y	Neutral	0.002
BRCA1	P38398-1.2	S1861A	Neutral	0.003
BRCA1	P38398-1.2	S1861C	Neutral	0.008
BRCA1	P38398-1.2	S1861D	Neutral	0.006
BRCA1	P38398-1.2	S1861E	Neutral	0.009
BRCA1	P38398-1.2	S1861F	Neutral	0.032
BRCA1	P38398-1.2	S1861G	Neutral	0.007
BRCA1	P38398-1.2	S1861H	Neutral	0.016
BRCA1	P38398-1.2	S1861I	Neutral	0.026
BRCA1	P38398-1.2	S1861K	Neutral	0.016
BRCA1	P38398-1.2	S1861L	Neutral	0.026
BRCA1	P38398-1.2	S1861M	Neutral	0.018
BRCA1	P38398-1.2	S1861N	Neutral	0.005
BRCA1	P38398-1.2	S1861P	Neutral	0.009
BRCA1	P38398-1.2	S1861Q	Neutral	0.01
BRCA1	P38398-1.2	S1861R	Neutral	0.031
BRCA1	P38398-1.2	S1861T	Neutral	0.005
BRCA1	P38398-1.2	S1861V	Neutral	0.017
BRCA1	P38398-1.2	S1861W	Neutral	0.082
BRCA1	P38398-1.2	S1861Y	Neutral	0.037
BRCA1	P38398-1.2	H1862A	Neutral	0.012
BRCA1	P38398-1.2	H1862C	Neutral	0.012
BRCA1	P38398-1.2	H1862D	Neutral	0.005
BRCA1	P38398-1.2	H1862E	Neutral	0.002
BRCA1	P38398-1.2	H1862F	Neutral	0.004
BRCA1	P38398-1.2	H1862G	Neutral	0.019
BRCA1	P38398-1.2	H1862I	Neutral	0.006
BRCA1	P38398-1.2	H1862K	Neutral	0.004
BRCA1	P38398-1.2	H1862L	Neutral	0.006
BRCA1	P38398-1.2	H1862M	Neutral	0.005
BRCA1	P38398-1.2	H1862N	Neutral	0.002
BRCA1	P38398-1.2	H1862P	Neutral	0.007
BRCA1	P38398-1.2	H1862Q	Neutral	0.002
BRCA1	P38398-1.2	H1862R	Neutral	0.004
BRCA1	P38398-1.2	H1862S	Neutral	0.008
BRCA1	P38398-1.2	H1862T	Neutral	0.007
BRCA1	P38398-1.2	H1862V	Neutral	0.008
BRCA1	P38398-1.2	H1862W	Neutral	0.01
BRCA1	P38398-1.2	H1862Y	Neutral	0.002
BRCA1	P38398-1.2	Y1863A	Neutral	0.068
BRCA1	P38398-1.2	Y1863C	Neutral	0.047
BRCA1	P38398-1.2	Y1863D	Neutral	0.057
BRCA1	P38398-1.2	Y1863E	Neutral	0.028
BRCA1	P38398-1.2	Y1863F	Neutral	0.003
BRCA1	P38398-1.2	Y1863G	Neutral	0.138
BRCA1	P38398-1.2	Y1863H	Neutral	0.005
BRCA1	P38398-1.2	Y1863I	Neutral	0.014
BRCA1	P38398-1.2	Y1863K	Neutral	0.016
BRCA1	P38398-1.2	Y1863L	Neutral	0.014
BRCA1	P38398-1.2	Y1863M	Neutral	0.014
BRCA1	P38398-1.2	Y1863N	Neutral	0.037
BRCA1	P38398-1.2	Y1863P	Neutral	0.06
BRCA1	P38398-1.2	Y1863Q	Neutral	0.017
BRCA1	P38398-1.2	Y1863R	Neutral	0.016
BRCA1	P38398-1.2	Y1863S	Neutral	0.06
BRCA1	P38398-1.2	Y1863T	Neutral	0.04
BRCA1	P38398-1.2	Y1863V	Neutral	0.022
BRCA1	P38398-1.2	Y1863W	Neutral	0.005