Gene	UniProt	Variant	Prediction	Score
BRCA1	P38398-1.2	A1608C	Neutral	1.069
BRCA1	P38398-1.2	A1608D	Neutral	0.984
BRCA1	P38398-1.2	A1608E	Neutral	1.026
BRCA1	P38398-1.2	A1608F	Neutral	0.984
BRCA1	P38398-1.2	A1608G	Neutral	1.069
BRCA1	P38398-1.2	A1608H	Neutral	0.984
BRCA1	P38398-1.2	A1608I	Neutral	1.026
BRCA1	P38398-1.2	A1608K	Neutral	1.026
BRCA1	P38398-1.2	A1608L	Neutral	1.026
BRCA1	P38398-1.2	A1608M	Neutral	1.026
BRCA1	P38398-1.2	A1608N	Neutral	0.984
BRCA1	P38398-1.2	A1608P	Neutral	1.026
BRCA1	P38398-1.2	A1608Q	Neutral	1.026
BRCA1	P38398-1.2	A1608R	Neutral	1.026
BRCA1	P38398-1.2	A1608S	Neutral	1.111
BRCA1	P38398-1.2	A1608T	Neutral	1.069
BRCA1	P38398-1.2	A1608V	Neutral	1.069
BRCA1	P38398-1.2	A1608W	Neutral	0.941
BRCA1	P38398-1.2	A1608Y	Neutral	0.984
BRCA1	P38398-1.2	E1609A	Neutral	1.174
BRCA1	P38398-1.2	E1609C	Neutral	1.046
BRCA1	P38398-1.2	E1609D	Neutral	1.301
BRCA1	P38398-1.2	E1609F	Neutral	1.088
BRCA1	P38398-1.2	E1609G	Neutral	1.131
BRCA1	P38398-1.2	E1609H	Neutral	1.216
BRCA1	P38398-1.2	E1609I	Neutral	1.088
BRCA1	P38398-1.2	E1609K	Neutral	1.259
BRCA1	P38398-1.2	E1609L	Neutral	1.088
BRCA1	P38398-1.2	E1609M	Neutral	1.131
BRCA1	P38398-1.2	E1609N	Neutral	1.216
BRCA1	P38398-1.2	E1609P	Neutral	1.174
BRCA1	P38398-1.2	E1609Q	Neutral	1.301
BRCA1	P38398-1.2	E1609R	Neutral	1.216
BRCA1	P38398-1.2	E1609S	Neutral	1.216
BRCA1	P38398-1.2	E1609T	Neutral	1.174
BRCA1	P38398-1.2	E1609V	Neutral	1.131
BRCA1	P38398-1.2	E1609W	Neutral	1.088
BRCA1	P38398-1.2	E1609Y	Neutral	1.131
BRCA1	P38398-1.2	S1610A	Neutral	1.265
BRCA1	P38398-1.2	S1610C	Neutral	1.179
BRCA1	P38398-1.2	S1610D	Neutral	1.222
BRCA1	P38398-1.2	S1610E	Neutral	1.222
BRCA1	P38398-1.2	S1610F	Neutral	1.137
BRCA1	P38398-1.2	S1610G	Neutral	1.222
BRCA1	P38398-1.2	S1610H	Neutral	1.179
BRCA1	P38398-1.2	S1610I	Neutral	1.137
BRCA1	P38398-1.2	S1610K	Neutral	1.222
BRCA1	P38398-1.2	S1610L	Neutral	1.137
BRCA1	P38398-1.2	S1610M	Neutral	1.179
BRCA1	P38398-1.2	S1610N	Neutral	1.265
BRCA1	P38398-1.2	S1610P	Neutral	1.179
BRCA1	P38398-1.2	S1610Q	Neutral	1.222
BRCA1	P38398-1.2	S1610R	Neutral	1.179
BRCA1	P38398-1.2	S1610T	Neutral	1.265
BRCA1	P38398-1.2	S1610V	Neutral	1.137
BRCA1	P38398-1.2	S1610W	Neutral	1.094
BRCA1	P38398-1.2	S1610Y	Neutral	1.137
BRCA1	P38398-1.2	A1611C	Neutral	1.141
BRCA1	P38398-1.2	A1611D	Neutral	1.056
BRCA1	P38398-1.2	A1611E	Neutral	1.098
BRCA1	P38398-1.2	A1611F	Neutral	1.056
BRCA1	P38398-1.2	A1611G	Neutral	1.141
BRCA1	P38398-1.2	A1611H	Neutral	1.056
BRCA1	P38398-1.2	A1611I	Neutral	1.098
BRCA1	P38398-1.2	A1611K	Neutral	1.098
BRCA1	P38398-1.2	A1611L	Neutral	1.098
BRCA1	P38398-1.2	A1611M	Neutral	1.098
BRCA1	P38398-1.2	A1611N	Neutral	1.056
BRCA1	P38398-1.2	A1611P	Neutral	1.098
BRCA1	P38398-1.2	A1611Q	Neutral	1.098
BRCA1	P38398-1.2	A1611R	Neutral	1.098
BRCA1	P38398-1.2	A1611S	Neutral	1.183
BRCA1	P38398-1.2	A1611T	Neutral	1.141
BRCA1	P38398-1.2	A1611V	Neutral	1.141
BRCA1	P38398-1.2	A1611W	Neutral	1.013
BRCA1	P38398-1.2	A1611Y	Neutral	1.056
BRCA1	P38398-1.2	Q1612A	Neutral	1.179
BRCA1	P38398-1.2	Q1612C	Neutral	1.094
BRCA1	P38398-1.2	Q1612D	Neutral	1.222
BRCA1	P38398-1.2	Q1612E	Neutral	1.307
BRCA1	P38398-1.2	Q1612F	Neutral	1.094
BRCA1	P38398-1.2	Q1612G	Neutral	1.136
BRCA1	P38398-1.2	Q1612H	Neutral	1.222
BRCA1	P38398-1.2	Q1612I	Neutral	1.094
BRCA1	P38398-1.2	Q1612K	Neutral	1.264
BRCA1	P38398-1.2	Q1612L	Neutral	1.136
BRCA1	P38398-1.2	Q1612M	Neutral	1.222
BRCA1	P38398-1.2	Q1612N	Neutral	1.222
BRCA1	P38398-1.2	Q1612P	Neutral	1.179
BRCA1	P38398-1.2	Q1612R	Neutral	1.264
BRCA1	P38398-1.2	Q1612S	Neutral	1.222
BRCA1	P38398-1.2	Q1612T	Neutral	1.179
BRCA1	P38398-1.2	Q1612V	Neutral	1.136
BRCA1	P38398-1.2	Q1612W	Neutral	1.136
BRCA1	P38398-1.2	Q1612Y	Neutral	1.179
BRCA1	P38398-1.2	S1613A	Neutral	1.332
BRCA1	P38398-1.2	S1613C	Neutral	1.247
BRCA1	P38398-1.2	S1613D	Neutral	1.289
BRCA1	P38398-1.2	S1613E	Neutral	1.289
BRCA1	P38398-1.2	S1613F	Neutral	1.204
BRCA1	P38398-1.2	S1613G	Neutral	1.289
BRCA1	P38398-1.2	S1613H	Neutral	1.247
BRCA1	P38398-1.2	S1613I	Neutral	1.204
BRCA1	P38398-1.2	S1613K	Neutral	1.289
BRCA1	P38398-1.2	S1613L	Neutral	1.204
BRCA1	P38398-1.2	S1613M	Neutral	1.247
BRCA1	P38398-1.2	S1613N	Neutral	1.332
BRCA1	P38398-1.2	S1613P	Neutral	1.247
BRCA1	P38398-1.2	S1613Q	Neutral	1.289
BRCA1	P38398-1.2	S1613R	Neutral	1.247
BRCA1	P38398-1.2	S1613T	Neutral	1.332
BRCA1	P38398-1.2	S1613V	Neutral	1.204
BRCA1	P38398-1.2	S1613W	Neutral	1.162
BRCA1	P38398-1.2	S1613Y	Neutral	1.204
BRCA1	P38398-1.2	P1614A	Neutral	0.895
BRCA1	P38398-1.2	P1614C	Neutral	0.809
BRCA1	P38398-1.2	P1614D	Neutral	0.895
BRCA1	P38398-1.2	P1614E	Neutral	0.895
BRCA1	P38398-1.2	P1614F	Neutral	0.767
BRCA1	P38398-1.2	P1614G	Neutral	0.852
BRCA1	P38398-1.2	P1614H	Neutral	0.852
BRCA1	P38398-1.2	P1614I	Neutral	0.809
BRCA1	P38398-1.2	P1614K	Neutral	0.895
BRCA1	P38398-1.2	P1614L	Neutral	0.809
BRCA1	P38398-1.2	P1614M	Neutral	0.852
BRCA1	P38398-1.2	P1614N	Neutral	0.852
BRCA1	P38398-1.2	P1614Q	Neutral	0.895
BRCA1	P38398-1.2	P1614R	Neutral	0.852
BRCA1	P38398-1.2	P1614S	Neutral	0.895
BRCA1	P38398-1.2	P1614T	Neutral	0.895
BRCA1	P38398-1.2	P1614V	Neutral	0.852
BRCA1	P38398-1.2	P1614W	Neutral	0.767
BRCA1	P38398-1.2	P1614Y	Neutral	0.809
BRCA1	P38398-1.2	A1615C	Neutral	0.89
BRCA1	P38398-1.2	A1615D	Neutral	0.804
BRCA1	P38398-1.2	A1615E	Neutral	0.847
BRCA1	P38398-1.2	A1615F	Neutral	0.804
BRCA1	P38398-1.2	A1615G	Neutral	0.89
BRCA1	P38398-1.2	A1615H	Neutral	0.804
BRCA1	P38398-1.2	A1615I	Neutral	0.847
BRCA1	P38398-1.2	A1615K	Neutral	0.847
BRCA1	P38398-1.2	A1615L	Neutral	0.847
BRCA1	P38398-1.2	A1615M	Neutral	0.847
BRCA1	P38398-1.2	A1615N	Neutral	0.804
BRCA1	P38398-1.2	A1615P	Neutral	0.847
BRCA1	P38398-1.2	A1615Q	Neutral	0.847
BRCA1	P38398-1.2	A1615R	Neutral	0.847
BRCA1	P38398-1.2	A1615S	Neutral	0.932
BRCA1	P38398-1.2	A1615T	Neutral	0.89
BRCA1	P38398-1.2	A1615V	Neutral	0.89
BRCA1	P38398-1.2	A1615W	Neutral	0.762
BRCA1	P38398-1.2	A1615Y	Neutral	0.804
BRCA1	P38398-1.2	A1616C	Neutral	1.117
BRCA1	P38398-1.2	A1616D	Neutral	1.032
BRCA1	P38398-1.2	A1616E	Neutral	1.074
BRCA1	P38398-1.2	A1616F	Neutral	1.032
BRCA1	P38398-1.2	A1616G	Neutral	1.117
BRCA1	P38398-1.2	A1616H	Neutral	1.032
BRCA1	P38398-1.2	A1616I	Neutral	1.074
BRCA1	P38398-1.2	A1616K	Neutral	1.074
BRCA1	P38398-1.2	A1616L	Neutral	1.074
BRCA1	P38398-1.2	A1616M	Neutral	1.074
BRCA1	P38398-1.2	A1616N	Neutral	1.032
BRCA1	P38398-1.2	A1616P	Neutral	1.074
BRCA1	P38398-1.2	A1616Q	Neutral	1.074
BRCA1	P38398-1.2	A1616R	Neutral	1.074
BRCA1	P38398-1.2	A1616S	Neutral	1.16
BRCA1	P38398-1.2	A1616T	Neutral	1.117
BRCA1	P38398-1.2	A1616V	Neutral	1.117
BRCA1	P38398-1.2	A1616W	Neutral	0.989
BRCA1	P38398-1.2	A1616Y	Neutral	1.032
BRCA1	P38398-1.2	A1617C	Neutral	1.01
BRCA1	P38398-1.2	A1617D	Neutral	0.925
BRCA1	P38398-1.2	A1617E	Neutral	0.967
BRCA1	P38398-1.2	A1617F	Neutral	0.925
BRCA1	P38398-1.2	A1617G	Neutral	1.01
BRCA1	P38398-1.2	A1617H	Neutral	0.925
BRCA1	P38398-1.2	A1617I	Neutral	0.967
BRCA1	P38398-1.2	A1617K	Neutral	0.967
BRCA1	P38398-1.2	A1617L	Neutral	0.967
BRCA1	P38398-1.2	A1617M	Neutral	0.967
BRCA1	P38398-1.2	A1617N	Neutral	0.925
BRCA1	P38398-1.2	A1617P	Neutral	0.967
BRCA1	P38398-1.2	A1617Q	Neutral	0.967
BRCA1	P38398-1.2	A1617R	Neutral	0.967
BRCA1	P38398-1.2	A1617S	Neutral	1.052
BRCA1	P38398-1.2	A1617T	Neutral	1.01
BRCA1	P38398-1.2	A1617V	Neutral	1.01
BRCA1	P38398-1.2	A1617W	Neutral	0.882
BRCA1	P38398-1.2	A1617Y	Neutral	0.925
BRCA1	P38398-1.2	H1618A	Neutral	0.843
BRCA1	P38398-1.2	H1618C	Neutral	0.8
BRCA1	P38398-1.2	H1618D	Neutral	0.886
BRCA1	P38398-1.2	H1618E	Neutral	0.928
BRCA1	P38398-1.2	H1618F	Neutral	0.886
BRCA1	P38398-1.2	H1618G	Neutral	0.843
BRCA1	P38398-1.2	H1618I	Neutral	0.8
BRCA1	P38398-1.2	H1618K	Neutral	0.886
BRCA1	P38398-1.2	H1618L	Neutral	0.8
BRCA1	P38398-1.2	H1618M	Neutral	0.843
BRCA1	P38398-1.2	H1618N	Neutral	0.971
BRCA1	P38398-1.2	H1618P	Neutral	0.843
BRCA1	P38398-1.2	H1618Q	Neutral	0.928
BRCA1	P38398-1.2	H1618R	Neutral	0.928
BRCA1	P38398-1.2	H1618S	Neutral	0.886
BRCA1	P38398-1.2	H1618T	Neutral	0.843
BRCA1	P38398-1.2	H1618V	Neutral	0.8
BRCA1	P38398-1.2	H1618W	Neutral	0.843
BRCA1	P38398-1.2	H1618Y	Neutral	1.013
BRCA1	P38398-1.2	T1619A	Neutral	1.318
BRCA1	P38398-1.2	T1619C	Neutral	1.275
BRCA1	P38398-1.2	T1619D	Neutral	1.275
BRCA1	P38398-1.2	T1619E	Neutral	1.275
BRCA1	P38398-1.2	T1619F	Neutral	1.233
BRCA1	P38398-1.2	T1619G	Neutral	1.233
BRCA1	P38398-1.2	T1619H	Neutral	1.233
BRCA1	P38398-1.2	T1619I	Neutral	1.275
BRCA1	P38398-1.2	T1619K	Neutral	1.275
BRCA1	P38398-1.2	T1619L	Neutral	1.275
BRCA1	P38398-1.2	T1619M	Neutral	1.275
BRCA1	P38398-1.2	T1619N	Neutral	1.318
BRCA1	P38398-1.2	T1619P	Neutral	1.275
BRCA1	P38398-1.2	T1619Q	Neutral	1.275
BRCA1	P38398-1.2	T1619R	Neutral	1.275
BRCA1	P38398-1.2	T1619S	Neutral	1.36
BRCA1	P38398-1.2	T1619V	Neutral	1.318
BRCA1	P38398-1.2	T1619W	Neutral	1.233
BRCA1	P38398-1.2	T1619Y	Neutral	1.233
BRCA1	P38398-1.2	T1620A	Neutral	1.183
BRCA1	P38398-1.2	T1620C	Neutral	1.14
BRCA1	P38398-1.2	T1620D	Neutral	1.14
BRCA1	P38398-1.2	T1620E	Neutral	1.14
BRCA1	P38398-1.2	T1620F	Neutral	1.097
BRCA1	P38398-1.2	T1620G	Neutral	1.097
BRCA1	P38398-1.2	T1620H	Neutral	1.097
BRCA1	P38398-1.2	T1620I	Neutral	1.14
BRCA1	P38398-1.2	T1620K	Neutral	1.14
BRCA1	P38398-1.2	T1620L	Neutral	1.14
BRCA1	P38398-1.2	T1620M	Neutral	1.14
BRCA1	P38398-1.2	T1620N	Neutral	1.183
BRCA1	P38398-1.2	T1620P	Neutral	1.14
BRCA1	P38398-1.2	T1620Q	Neutral	1.14
BRCA1	P38398-1.2	T1620R	Neutral	1.14
BRCA1	P38398-1.2	T1620S	Neutral	1.225
BRCA1	P38398-1.2	T1620V	Neutral	1.183
BRCA1	P38398-1.2	T1620W	Neutral	1.097
BRCA1	P38398-1.2	T1620Y	Neutral	1.097
BRCA1	P38398-1.2	D1621A	Neutral	1.599
BRCA1	P38398-1.2	D1621C	Neutral	1.557
BRCA1	P38398-1.2	D1621E	Neutral	1.769
BRCA1	P38398-1.2	D1621F	Neutral	1.557
BRCA1	P38398-1.2	D1621G	Neutral	1.642
BRCA1	P38398-1.2	D1621H	Neutral	1.642
BRCA1	P38398-1.2	D1621I	Neutral	1.557
BRCA1	P38398-1.2	D1621K	Neutral	1.642
BRCA1	P38398-1.2	D1621L	Neutral	1.514
BRCA1	P38398-1.2	D1621M	Neutral	1.557
BRCA1	P38398-1.2	D1621N	Neutral	1.727
BRCA1	P38398-1.2	D1621P	Neutral	1.642
BRCA1	P38398-1.2	D1621Q	Neutral	1.684
BRCA1	P38398-1.2	D1621R	Neutral	1.599
BRCA1	P38398-1.2	D1621S	Neutral	1.684
BRCA1	P38398-1.2	D1621T	Neutral	1.642
BRCA1	P38398-1.2	D1621V	Neutral	1.557
BRCA1	P38398-1.2	D1621W	Neutral	1.514
BRCA1	P38398-1.2	D1621Y	Neutral	1.557
BRCA1	P38398-1.2	T1622A	Neutral	1.006
BRCA1	P38398-1.2	T1622C	Neutral	0.964
BRCA1	P38398-1.2	T1622D	Neutral	0.964
BRCA1	P38398-1.2	T1622E	Neutral	0.964
BRCA1	P38398-1.2	T1622F	Neutral	0.921
BRCA1	P38398-1.2	T1622G	Neutral	0.921
BRCA1	P38398-1.2	T1622H	Neutral	0.921
BRCA1	P38398-1.2	T1622I	Neutral	0.964
BRCA1	P38398-1.2	T1622K	Neutral	0.964
BRCA1	P38398-1.2	T1622L	Neutral	0.964
BRCA1	P38398-1.2	T1622M	Neutral	0.964
BRCA1	P38398-1.2	T1622N	Neutral	1.006
BRCA1	P38398-1.2	T1622P	Neutral	0.964
BRCA1	P38398-1.2	T1622Q	Neutral	0.964
BRCA1	P38398-1.2	T1622R	Neutral	0.964
BRCA1	P38398-1.2	T1622S	Neutral	1.049
BRCA1	P38398-1.2	T1622V	Neutral	1.006
BRCA1	P38398-1.2	T1622W	Neutral	0.921
BRCA1	P38398-1.2	T1622Y	Neutral	0.921
BRCA1	P38398-1.2	A1623C	Neutral	0.904
BRCA1	P38398-1.2	A1623D	Neutral	0.819
BRCA1	P38398-1.2	A1623E	Neutral	0.861
BRCA1	P38398-1.2	A1623F	Neutral	0.819
BRCA1	P38398-1.2	A1623G	Neutral	0.904
BRCA1	P38398-1.2	A1623H	Neutral	0.819
BRCA1	P38398-1.2	A1623I	Neutral	0.861
BRCA1	P38398-1.2	A1623K	Neutral	0.861
BRCA1	P38398-1.2	A1623L	Neutral	0.861
BRCA1	P38398-1.2	A1623M	Neutral	0.861
BRCA1	P38398-1.2	A1623N	Neutral	0.819
BRCA1	P38398-1.2	A1623P	Neutral	0.861
BRCA1	P38398-1.2	A1623Q	Neutral	0.861
BRCA1	P38398-1.2	A1623R	Neutral	0.861
BRCA1	P38398-1.2	A1623S	Neutral	0.946
BRCA1	P38398-1.2	A1623T	Neutral	0.904
BRCA1	P38398-1.2	A1623V	Neutral	0.904
BRCA1	P38398-1.2	A1623W	Neutral	0.776
BRCA1	P38398-1.2	A1623Y	Neutral	0.819
BRCA1	P38398-1.2	G1624A	Neutral	1.031
BRCA1	P38398-1.2	G1624C	Neutral	0.903
BRCA1	P38398-1.2	G1624D	Neutral	0.988
BRCA1	P38398-1.2	G1624E	Neutral	0.946
BRCA1	P38398-1.2	G1624F	Neutral	0.903
BRCA1	P38398-1.2	G1624H	Neutral	0.946
BRCA1	P38398-1.2	G1624I	Neutral	0.86
BRCA1	P38398-1.2	G1624K	Neutral	0.946
BRCA1	P38398-1.2	G1624L	Neutral	0.86
BRCA1	P38398-1.2	G1624M	Neutral	0.903
BRCA1	P38398-1.2	G1624N	Neutral	1.031
BRCA1	P38398-1.2	G1624P	Neutral	0.946
BRCA1	P38398-1.2	G1624Q	Neutral	0.946
BRCA1	P38398-1.2	G1624R	Neutral	0.946
BRCA1	P38398-1.2	G1624S	Neutral	1.031
BRCA1	P38398-1.2	G1624T	Neutral	0.946
BRCA1	P38398-1.2	G1624V	Neutral	0.903
BRCA1	P38398-1.2	G1624W	Neutral	0.946
BRCA1	P38398-1.2	G1624Y	Neutral	0.903
BRCA1	P38398-1.2	Y1625A	Neutral	0.581
BRCA1	P38398-1.2	Y1625C	Neutral	0.581
BRCA1	P38398-1.2	Y1625D	Neutral	0.538
BRCA1	P38398-1.2	Y1625E	Neutral	0.581
BRCA1	P38398-1.2	Y1625F	Neutral	0.794
BRCA1	P38398-1.2	Y1625G	Neutral	0.538
BRCA1	P38398-1.2	Y1625H	Neutral	0.751
BRCA1	P38398-1.2	Y1625I	Neutral	0.623
BRCA1	P38398-1.2	Y1625K	Neutral	0.581
BRCA1	P38398-1.2	Y1625L	Neutral	0.623
BRCA1	P38398-1.2	Y1625M	Neutral	0.623
BRCA1	P38398-1.2	Y1625N	Neutral	0.581
BRCA1	P38398-1.2	Y1625P	Neutral	0.538
BRCA1	P38398-1.2	Y1625Q	Neutral	0.623
BRCA1	P38398-1.2	Y1625R	Neutral	0.581
BRCA1	P38398-1.2	Y1625S	Neutral	0.581
BRCA1	P38398-1.2	Y1625T	Neutral	0.581
BRCA1	P38398-1.2	Y1625V	Neutral	0.623
BRCA1	P38398-1.2	Y1625W	Neutral	0.751
BRCA1	P38398-1.2	N1626A	Neutral	0.986
BRCA1	P38398-1.2	N1626C	Neutral	0.944
BRCA1	P38398-1.2	N1626D	Neutral	1.114
BRCA1	P38398-1.2	N1626E	Neutral	1.072
BRCA1	P38398-1.2	N1626F	Neutral	0.944
BRCA1	P38398-1.2	N1626G	Neutral	1.072
BRCA1	P38398-1.2	N1626H	Neutral	1.114
BRCA1	P38398-1.2	N1626I	Neutral	0.944
BRCA1	P38398-1.2	N1626K	Neutral	1.072
BRCA1	P38398-1.2	N1626L	Neutral	0.944
BRCA1	P38398-1.2	N1626M	Neutral	0.986
BRCA1	P38398-1.2	N1626P	Neutral	0.986
BRCA1	P38398-1.2	N1626Q	Neutral	1.072
BRCA1	P38398-1.2	N1626R	Neutral	1.072
BRCA1	P38398-1.2	N1626S	Neutral	1.114
BRCA1	P38398-1.2	N1626T	Neutral	1.072
BRCA1	P38398-1.2	N1626V	Neutral	0.944
BRCA1	P38398-1.2	N1626W	Neutral	0.901
BRCA1	P38398-1.2	N1626Y	Neutral	0.986
BRCA1	P38398-1.2	A1627C	Neutral	1.133
BRCA1	P38398-1.2	A1627D	Neutral	1.048
BRCA1	P38398-1.2	A1627E	Neutral	1.09
BRCA1	P38398-1.2	A1627F	Neutral	1.048
BRCA1	P38398-1.2	A1627G	Neutral	1.133
BRCA1	P38398-1.2	A1627H	Neutral	1.048
BRCA1	P38398-1.2	A1627I	Neutral	1.09
BRCA1	P38398-1.2	A1627K	Neutral	1.09
BRCA1	P38398-1.2	A1627L	Neutral	1.09
BRCA1	P38398-1.2	A1627M	Neutral	1.09
BRCA1	P38398-1.2	A1627N	Neutral	1.048
BRCA1	P38398-1.2	A1627P	Neutral	1.09
BRCA1	P38398-1.2	A1627Q	Neutral	1.09
BRCA1	P38398-1.2	A1627R	Neutral	1.09
BRCA1	P38398-1.2	A1627S	Neutral	1.175
BRCA1	P38398-1.2	A1627T	Neutral	1.133
BRCA1	P38398-1.2	A1627V	Neutral	1.133
BRCA1	P38398-1.2	A1627W	Neutral	1.005
BRCA1	P38398-1.2	A1627Y	Neutral	1.048
BRCA1	P38398-1.2	M1628A	Neutral	0.883
BRCA1	P38398-1.2	M1628C	Neutral	0.883
BRCA1	P38398-1.2	M1628D	Neutral	0.798
BRCA1	P38398-1.2	M1628E	Neutral	0.84
BRCA1	P38398-1.2	M1628F	Neutral	0.926
BRCA1	P38398-1.2	M1628G	Neutral	0.798
BRCA1	P38398-1.2	M1628H	Neutral	0.84
BRCA1	P38398-1.2	M1628I	Neutral	0.968
BRCA1	P38398-1.2	M1628K	Neutral	0.883
BRCA1	P38398-1.2	M1628L	Neutral	1.011
BRCA1	P38398-1.2	M1628N	Neutral	0.84
BRCA1	P38398-1.2	M1628P	Neutral	0.84
BRCA1	P38398-1.2	M1628Q	Neutral	0.926
BRCA1	P38398-1.2	M1628R	Neutral	0.883
BRCA1	P38398-1.2	M1628S	Neutral	0.883
BRCA1	P38398-1.2	M1628T	Neutral	0.883
BRCA1	P38398-1.2	M1628V	Neutral	0.968
BRCA1	P38398-1.2	M1628W	Neutral	0.883
BRCA1	P38398-1.2	M1628Y	Neutral	0.883
BRCA1	P38398-1.2	E1629A	Neutral	1.228
BRCA1	P38398-1.2	E1629C	Neutral	1.1
BRCA1	P38398-1.2	E1629D	Neutral	1.356
BRCA1	P38398-1.2	E1629F	Neutral	1.143
BRCA1	P38398-1.2	E1629G	Neutral	1.185
BRCA1	P38398-1.2	E1629H	Neutral	1.27
BRCA1	P38398-1.2	E1629I	Neutral	1.143
BRCA1	P38398-1.2	E1629K	Neutral	1.313
BRCA1	P38398-1.2	E1629L	Neutral	1.143
BRCA1	P38398-1.2	E1629M	Neutral	1.185
BRCA1	P38398-1.2	E1629N	Neutral	1.27
BRCA1	P38398-1.2	E1629P	Neutral	1.228
BRCA1	P38398-1.2	E1629Q	Neutral	1.356
BRCA1	P38398-1.2	E1629R	Neutral	1.27
BRCA1	P38398-1.2	E1629S	Neutral	1.27
BRCA1	P38398-1.2	E1629T	Neutral	1.228
BRCA1	P38398-1.2	E1629V	Neutral	1.185
BRCA1	P38398-1.2	E1629W	Neutral	1.143
BRCA1	P38398-1.2	E1629Y	Neutral	1.185
BRCA1	P38398-1.2	E1630A	Neutral	1.335
BRCA1	P38398-1.2	E1630C	Neutral	1.208
BRCA1	P38398-1.2	E1630D	Neutral	1.463
BRCA1	P38398-1.2	E1630F	Neutral	1.25
BRCA1	P38398-1.2	E1630G	Neutral	1.293
BRCA1	P38398-1.2	E1630H	Neutral	1.378
BRCA1	P38398-1.2	E1630I	Neutral	1.25
BRCA1	P38398-1.2	E1630K	Neutral	1.421
BRCA1	P38398-1.2	E1630L	Neutral	1.25
BRCA1	P38398-1.2	E1630M	Neutral	1.293
BRCA1	P38398-1.2	E1630N	Neutral	1.378
BRCA1	P38398-1.2	E1630P	Neutral	1.335
BRCA1	P38398-1.2	E1630Q	Neutral	1.463
BRCA1	P38398-1.2	E1630R	Neutral	1.378
BRCA1	P38398-1.2	E1630S	Neutral	1.378
BRCA1	P38398-1.2	E1630T	Neutral	1.335
BRCA1	P38398-1.2	E1630V	Neutral	1.293
BRCA1	P38398-1.2	E1630W	Neutral	1.25
BRCA1	P38398-1.2	E1630Y	Neutral	1.293
BRCA1	P38398-1.2	S1631A	Neutral	1.263
BRCA1	P38398-1.2	S1631C	Neutral	1.178
BRCA1	P38398-1.2	S1631D	Neutral	1.22
BRCA1	P38398-1.2	S1631E	Neutral	1.22
BRCA1	P38398-1.2	S1631F	Neutral	1.135
BRCA1	P38398-1.2	S1631G	Neutral	1.22
BRCA1	P38398-1.2	S1631H	Neutral	1.178
BRCA1	P38398-1.2	S1631I	Neutral	1.135
BRCA1	P38398-1.2	S1631K	Neutral	1.22
BRCA1	P38398-1.2	S1631L	Neutral	1.135
BRCA1	P38398-1.2	S1631M	Neutral	1.178
BRCA1	P38398-1.2	S1631N	Neutral	1.263
BRCA1	P38398-1.2	S1631P	Neutral	1.178
BRCA1	P38398-1.2	S1631Q	Neutral	1.22
BRCA1	P38398-1.2	S1631R	Neutral	1.178
BRCA1	P38398-1.2	S1631T	Neutral	1.263
BRCA1	P38398-1.2	S1631V	Neutral	1.135
BRCA1	P38398-1.2	S1631W	Neutral	1.093
BRCA1	P38398-1.2	S1631Y	Neutral	1.135
BRCA1	P38398-1.2	V1632A	Neutral	1.181
BRCA1	P38398-1.2	V1632C	Neutral	1.138
BRCA1	P38398-1.2	V1632D	Neutral	1.053
BRCA1	P38398-1.2	V1632E	Neutral	1.096
BRCA1	P38398-1.2	V1632F	Neutral	1.138
BRCA1	P38398-1.2	V1632G	Neutral	1.053
BRCA1	P38398-1.2	V1632H	Neutral	1.053
BRCA1	P38398-1.2	V1632I	Neutral	1.308
BRCA1	P38398-1.2	V1632K	Neutral	1.096
BRCA1	P38398-1.2	V1632L	Neutral	1.223
BRCA1	P38398-1.2	V1632M	Neutral	1.223
BRCA1	P38398-1.2	V1632N	Neutral	1.053
BRCA1	P38398-1.2	V1632P	Neutral	1.096
BRCA1	P38398-1.2	V1632Q	Neutral	1.096
BRCA1	P38398-1.2	V1632R	Neutral	1.053
BRCA1	P38398-1.2	V1632S	Neutral	1.096
BRCA1	P38398-1.2	V1632T	Neutral	1.181
BRCA1	P38398-1.2	V1632W	Neutral	1.053
BRCA1	P38398-1.2	V1632Y	Neutral	1.138
BRCA1	P38398-1.2	S1633A	Neutral	1.433
BRCA1	P38398-1.2	S1633C	Neutral	1.348
BRCA1	P38398-1.2	S1633D	Neutral	1.39
BRCA1	P38398-1.2	S1633E	Neutral	1.39
BRCA1	P38398-1.2	S1633F	Neutral	1.305
BRCA1	P38398-1.2	S1633G	Neutral	1.39
BRCA1	P38398-1.2	S1633H	Neutral	1.348
BRCA1	P38398-1.2	S1633I	Neutral	1.305
BRCA1	P38398-1.2	S1633K	Neutral	1.39
BRCA1	P38398-1.2	S1633L	Neutral	1.305
BRCA1	P38398-1.2	S1633M	Neutral	1.348
BRCA1	P38398-1.2	S1633N	Neutral	1.433
BRCA1	P38398-1.2	S1633P	Neutral	1.348
BRCA1	P38398-1.2	S1633Q	Neutral	1.39
BRCA1	P38398-1.2	S1633R	Neutral	1.348
BRCA1	P38398-1.2	S1633T	Neutral	1.433
BRCA1	P38398-1.2	S1633V	Neutral	1.305
BRCA1	P38398-1.2	S1633W	Neutral	1.262
BRCA1	P38398-1.2	S1633Y	Neutral	1.305
BRCA1	P38398-1.2	R1634A	Neutral	1.231
BRCA1	P38398-1.2	R1634C	Neutral	1.146
BRCA1	P38398-1.2	R1634D	Neutral	1.188
BRCA1	P38398-1.2	R1634E	Neutral	1.274
BRCA1	P38398-1.2	R1634F	Neutral	1.146
BRCA1	P38398-1.2	R1634G	Neutral	1.188
BRCA1	P38398-1.2	R1634H	Neutral	1.274
BRCA1	P38398-1.2	R1634I	Neutral	1.146
BRCA1	P38398-1.2	R1634K	Neutral	1.359
BRCA1	P38398-1.2	R1634L	Neutral	1.188
BRCA1	P38398-1.2	R1634M	Neutral	1.231
BRCA1	P38398-1.2	R1634N	Neutral	1.274
BRCA1	P38398-1.2	R1634P	Neutral	1.188
BRCA1	P38398-1.2	R1634Q	Neutral	1.316
BRCA1	P38398-1.2	R1634S	Neutral	1.231
BRCA1	P38398-1.2	R1634T	Neutral	1.231
BRCA1	P38398-1.2	R1634V	Neutral	1.146
BRCA1	P38398-1.2	R1634W	Neutral	1.146
BRCA1	P38398-1.2	R1634Y	Neutral	1.188
BRCA1	P38398-1.2	E1635A	Neutral	1.241
BRCA1	P38398-1.2	E1635C	Neutral	1.114
BRCA1	P38398-1.2	E1635D	Neutral	1.369
BRCA1	P38398-1.2	E1635F	Neutral	1.156
BRCA1	P38398-1.2	E1635G	Neutral	1.199
BRCA1	P38398-1.2	E1635H	Neutral	1.284
BRCA1	P38398-1.2	E1635I	Neutral	1.156
BRCA1	P38398-1.2	E1635K	Neutral	1.327
BRCA1	P38398-1.2	E1635L	Neutral	1.156
BRCA1	P38398-1.2	E1635M	Neutral	1.199
BRCA1	P38398-1.2	E1635N	Neutral	1.284
BRCA1	P38398-1.2	E1635P	Neutral	1.241
BRCA1	P38398-1.2	E1635Q	Neutral	1.369
BRCA1	P38398-1.2	E1635R	Neutral	1.284
BRCA1	P38398-1.2	E1635S	Neutral	1.284
BRCA1	P38398-1.2	E1635T	Neutral	1.241
BRCA1	P38398-1.2	E1635V	Neutral	1.199
BRCA1	P38398-1.2	E1635W	Neutral	1.156
BRCA1	P38398-1.2	E1635Y	Neutral	1.199
BRCA1	P38398-1.2	K1636A	Neutral	1.001
BRCA1	P38398-1.2	K1636C	Neutral	0.916
BRCA1	P38398-1.2	K1636D	Neutral	1.001
BRCA1	P38398-1.2	K1636E	Neutral	1.087
BRCA1	P38398-1.2	K1636F	Neutral	0.916
BRCA1	P38398-1.2	K1636G	Neutral	0.959
BRCA1	P38398-1.2	K1636H	Neutral	1.001
BRCA1	P38398-1.2	K1636I	Neutral	0.916
BRCA1	P38398-1.2	K1636L	Neutral	0.959
BRCA1	P38398-1.2	K1636M	Neutral	1.001
BRCA1	P38398-1.2	K1636N	Neutral	1.044
BRCA1	P38398-1.2	K1636P	Neutral	1.001
BRCA1	P38398-1.2	K1636Q	Neutral	1.087
BRCA1	P38398-1.2	K1636R	Neutral	1.129
BRCA1	P38398-1.2	K1636S	Neutral	1.044
BRCA1	P38398-1.2	K1636T	Neutral	1.001
BRCA1	P38398-1.2	K1636V	Neutral	0.959
BRCA1	P38398-1.2	K1636W	Neutral	0.916
BRCA1	P38398-1.2	K1636Y	Neutral	0.959
BRCA1	P38398-1.2	P1637A	Neutral	1.0
BRCA1	P38398-1.2	P1637C	Neutral	0.915
BRCA1	P38398-1.2	P1637D	Neutral	1.0
BRCA1	P38398-1.2	P1637E	Neutral	1.0
BRCA1	P38398-1.2	P1637F	Neutral	0.873
BRCA1	P38398-1.2	P1637G	Neutral	0.958
BRCA1	P38398-1.2	P1637H	Neutral	0.958
BRCA1	P38398-1.2	P1637I	Neutral	0.915
BRCA1	P38398-1.2	P1637K	Neutral	1.0
BRCA1	P38398-1.2	P1637L	Neutral	0.915
BRCA1	P38398-1.2	P1637M	Neutral	0.958
BRCA1	P38398-1.2	P1637N	Neutral	0.958
BRCA1	P38398-1.2	P1637Q	Neutral	1.0
BRCA1	P38398-1.2	P1637R	Neutral	0.958
BRCA1	P38398-1.2	P1637S	Neutral	1.0
BRCA1	P38398-1.2	P1637T	Neutral	1.0
BRCA1	P38398-1.2	P1637V	Neutral	0.958
BRCA1	P38398-1.2	P1637W	Neutral	0.873
BRCA1	P38398-1.2	P1637Y	Neutral	0.915
BRCA1	P38398-1.2	E1638A	Neutral	1.099
BRCA1	P38398-1.2	E1638C	Neutral	0.971
BRCA1	P38398-1.2	E1638D	Neutral	1.226
BRCA1	P38398-1.2	E1638F	Neutral	1.014
BRCA1	P38398-1.2	E1638G	Neutral	1.056
BRCA1	P38398-1.2	E1638H	Neutral	1.141
BRCA1	P38398-1.2	E1638I	Neutral	1.014
BRCA1	P38398-1.2	E1638K	Neutral	1.184
BRCA1	P38398-1.2	E1638L	Neutral	1.014
BRCA1	P38398-1.2	E1638M	Neutral	1.056
BRCA1	P38398-1.2	E1638N	Neutral	1.141
BRCA1	P38398-1.2	E1638P	Neutral	1.099
BRCA1	P38398-1.2	E1638Q	Neutral	1.226
BRCA1	P38398-1.2	E1638R	Neutral	1.141
BRCA1	P38398-1.2	E1638S	Neutral	1.141
BRCA1	P38398-1.2	E1638T	Neutral	1.099
BRCA1	P38398-1.2	E1638V	Neutral	1.056
BRCA1	P38398-1.2	E1638W	Neutral	1.014
BRCA1	P38398-1.2	E1638Y	Neutral	1.056
BRCA1	P38398-1.2	L1639A	Neutral	1.29
BRCA1	P38398-1.2	L1639C	Neutral	1.29
BRCA1	P38398-1.2	L1639D	Neutral	1.162
BRCA1	P38398-1.2	L1639E	Neutral	1.205
BRCA1	P38398-1.2	L1639F	Neutral	1.332
BRCA1	P38398-1.2	L1639G	Neutral	1.162
BRCA1	P38398-1.2	L1639H	Neutral	1.205
BRCA1	P38398-1.2	L1639I	Neutral	1.417
BRCA1	P38398-1.2	L1639K	Neutral	1.247
BRCA1	P38398-1.2	L1639M	Neutral	1.417
BRCA1	P38398-1.2	L1639N	Neutral	1.205
BRCA1	P38398-1.2	L1639P	Neutral	1.205
BRCA1	P38398-1.2	L1639Q	Neutral	1.247
BRCA1	P38398-1.2	L1639R	Neutral	1.247
BRCA1	P38398-1.2	L1639S	Neutral	1.247
BRCA1	P38398-1.2	L1639T	Neutral	1.29
BRCA1	P38398-1.2	L1639V	Neutral	1.375
BRCA1	P38398-1.2	L1639W	Neutral	1.247
BRCA1	P38398-1.2	L1639Y	Neutral	1.29
BRCA1	P38398-1.2	T1640A	Neutral	1.153
BRCA1	P38398-1.2	T1640C	Neutral	1.11
BRCA1	P38398-1.2	T1640D	Neutral	1.11
BRCA1	P38398-1.2	T1640E	Neutral	1.11
BRCA1	P38398-1.2	T1640F	Neutral	1.067
BRCA1	P38398-1.2	T1640G	Neutral	1.067
BRCA1	P38398-1.2	T1640H	Neutral	1.067
BRCA1	P38398-1.2	T1640I	Neutral	1.11
BRCA1	P38398-1.2	T1640K	Neutral	1.11
BRCA1	P38398-1.2	T1640L	Neutral	1.11
BRCA1	P38398-1.2	T1640M	Neutral	1.11
BRCA1	P38398-1.2	T1640N	Neutral	1.153
BRCA1	P38398-1.2	T1640P	Neutral	1.11
BRCA1	P38398-1.2	T1640Q	Neutral	1.11
BRCA1	P38398-1.2	T1640R	Neutral	1.11
BRCA1	P38398-1.2	T1640S	Neutral	1.195
BRCA1	P38398-1.2	T1640V	Neutral	1.153
BRCA1	P38398-1.2	T1640W	Neutral	1.067
BRCA1	P38398-1.2	T1640Y	Neutral	1.067
BRCA1	P38398-1.2	A1641C	Neutral	1.099
BRCA1	P38398-1.2	A1641D	Neutral	1.014
BRCA1	P38398-1.2	A1641E	Neutral	1.056
BRCA1	P38398-1.2	A1641F	Neutral	1.014
BRCA1	P38398-1.2	A1641G	Neutral	1.099
BRCA1	P38398-1.2	A1641H	Neutral	1.014
BRCA1	P38398-1.2	A1641I	Neutral	1.056
BRCA1	P38398-1.2	A1641K	Neutral	1.056
BRCA1	P38398-1.2	A1641L	Neutral	1.056
BRCA1	P38398-1.2	A1641M	Neutral	1.056
BRCA1	P38398-1.2	A1641N	Neutral	1.014
BRCA1	P38398-1.2	A1641P	Neutral	1.056
BRCA1	P38398-1.2	A1641Q	Neutral	1.056
BRCA1	P38398-1.2	A1641R	Neutral	1.056
BRCA1	P38398-1.2	A1641S	Neutral	1.142
BRCA1	P38398-1.2	A1641T	Neutral	1.099
BRCA1	P38398-1.2	A1641V	Neutral	1.099
BRCA1	P38398-1.2	A1641W	Neutral	0.971
BRCA1	P38398-1.2	A1641Y	Neutral	1.014
BRCA1	P38398-1.2	S1642A	Neutral	1.11
BRCA1	P38398-1.2	S1642C	Neutral	1.025
BRCA1	P38398-1.2	S1642D	Neutral	1.068
BRCA1	P38398-1.2	S1642E	Neutral	1.068
BRCA1	P38398-1.2	S1642F	Neutral	0.983
BRCA1	P38398-1.2	S1642G	Neutral	1.068
BRCA1	P38398-1.2	S1642H	Neutral	1.025
BRCA1	P38398-1.2	S1642I	Neutral	0.983
BRCA1	P38398-1.2	S1642K	Neutral	1.068
BRCA1	P38398-1.2	S1642L	Neutral	0.983
BRCA1	P38398-1.2	S1642M	Neutral	1.025
BRCA1	P38398-1.2	S1642N	Neutral	1.11
BRCA1	P38398-1.2	S1642P	Neutral	1.025
BRCA1	P38398-1.2	S1642Q	Neutral	1.068
BRCA1	P38398-1.2	S1642R	Neutral	1.025
BRCA1	P38398-1.2	S1642T	Neutral	1.11
BRCA1	P38398-1.2	S1642V	Neutral	0.983
BRCA1	P38398-1.2	S1642W	Neutral	0.94
BRCA1	P38398-1.2	S1642Y	Neutral	0.983
BRCA1	P38398-1.2	T1643A	Neutral	1.174
BRCA1	P38398-1.2	T1643C	Neutral	1.131
BRCA1	P38398-1.2	T1643D	Neutral	1.131
BRCA1	P38398-1.2	T1643E	Neutral	1.131
BRCA1	P38398-1.2	T1643F	Neutral	1.088
BRCA1	P38398-1.2	T1643G	Neutral	1.088
BRCA1	P38398-1.2	T1643H	Neutral	1.088
BRCA1	P38398-1.2	T1643I	Neutral	1.131
BRCA1	P38398-1.2	T1643K	Neutral	1.131
BRCA1	P38398-1.2	T1643L	Neutral	1.131
BRCA1	P38398-1.2	T1643M	Neutral	1.131
BRCA1	P38398-1.2	T1643N	Neutral	1.174
BRCA1	P38398-1.2	T1643P	Neutral	1.131
BRCA1	P38398-1.2	T1643Q	Neutral	1.131
BRCA1	P38398-1.2	T1643R	Neutral	1.131
BRCA1	P38398-1.2	T1643S	Neutral	1.216
BRCA1	P38398-1.2	T1643V	Neutral	1.174
BRCA1	P38398-1.2	T1643W	Neutral	1.088
BRCA1	P38398-1.2	T1643Y	Neutral	1.088
BRCA1	P38398-1.2	E1644A	Neutral	1.244
BRCA1	P38398-1.2	E1644C	Neutral	1.116
BRCA1	P38398-1.2	E1644D	Neutral	1.372
BRCA1	P38398-1.2	E1644F	Neutral	1.159
BRCA1	P38398-1.2	E1644G	Neutral	1.202
BRCA1	P38398-1.2	E1644H	Neutral	1.287
BRCA1	P38398-1.2	E1644I	Neutral	1.159
BRCA1	P38398-1.2	E1644K	Neutral	1.329
BRCA1	P38398-1.2	E1644L	Neutral	1.159
BRCA1	P38398-1.2	E1644M	Neutral	1.202
BRCA1	P38398-1.2	E1644N	Neutral	1.287
BRCA1	P38398-1.2	E1644P	Neutral	1.244
BRCA1	P38398-1.2	E1644Q	Neutral	1.372
BRCA1	P38398-1.2	E1644R	Neutral	1.287
BRCA1	P38398-1.2	E1644S	Neutral	1.287
BRCA1	P38398-1.2	E1644T	Neutral	1.244
BRCA1	P38398-1.2	E1644V	Neutral	1.202
BRCA1	P38398-1.2	E1644W	Neutral	1.159
BRCA1	P38398-1.2	E1644Y	Neutral	1.202
BRCA1	P38398-1.2	R1645A	Neutral	0.949
BRCA1	P38398-1.2	R1645C	Neutral	0.863
BRCA1	P38398-1.2	R1645D	Neutral	0.906
BRCA1	P38398-1.2	R1645E	Neutral	0.991
BRCA1	P38398-1.2	R1645F	Neutral	0.863
BRCA1	P38398-1.2	R1645G	Neutral	0.906
BRCA1	P38398-1.2	R1645H	Neutral	0.991
BRCA1	P38398-1.2	R1645I	Neutral	0.863
BRCA1	P38398-1.2	R1645K	Neutral	1.076
BRCA1	P38398-1.2	R1645L	Neutral	0.906
BRCA1	P38398-1.2	R1645M	Neutral	0.949
BRCA1	P38398-1.2	R1645N	Neutral	0.991
BRCA1	P38398-1.2	R1645P	Neutral	0.906
BRCA1	P38398-1.2	R1645Q	Neutral	1.034
BRCA1	P38398-1.2	R1645S	Neutral	0.949
BRCA1	P38398-1.2	R1645T	Neutral	0.949
BRCA1	P38398-1.2	R1645V	Neutral	0.863
BRCA1	P38398-1.2	R1645W	Neutral	0.863
BRCA1	P38398-1.2	R1645Y	Neutral	0.906
BRCA1	P38398-1.2	V1646A	Neutral	1.09
BRCA1	P38398-1.2	V1646C	Neutral	1.048
BRCA1	P38398-1.2	V1646D	Neutral	0.963
BRCA1	P38398-1.2	V1646E	Neutral	1.005
BRCA1	P38398-1.2	V1646F	Neutral	1.048
BRCA1	P38398-1.2	V1646G	Neutral	0.963
BRCA1	P38398-1.2	V1646H	Neutral	0.963
BRCA1	P38398-1.2	V1646I	Neutral	1.218
BRCA1	P38398-1.2	V1646K	Neutral	1.005
BRCA1	P38398-1.2	V1646L	Neutral	1.133
BRCA1	P38398-1.2	V1646M	Neutral	1.133
BRCA1	P38398-1.2	V1646N	Neutral	0.963
BRCA1	P38398-1.2	V1646P	Neutral	1.005
BRCA1	P38398-1.2	V1646Q	Neutral	1.005
BRCA1	P38398-1.2	V1646R	Neutral	0.963
BRCA1	P38398-1.2	V1646S	Neutral	1.005
BRCA1	P38398-1.2	V1646T	Neutral	1.09
BRCA1	P38398-1.2	V1646W	Neutral	0.963
BRCA1	P38398-1.2	V1646Y	Neutral	1.048
BRCA1	P38398-1.2	N1647A	Neutral	1.052
BRCA1	P38398-1.2	N1647C	Neutral	1.009
BRCA1	P38398-1.2	N1647D	Neutral	1.179
BRCA1	P38398-1.2	N1647E	Neutral	1.137
BRCA1	P38398-1.2	N1647F	Neutral	1.009
BRCA1	P38398-1.2	N1647G	Neutral	1.137
BRCA1	P38398-1.2	N1647H	Neutral	1.179
BRCA1	P38398-1.2	N1647I	Neutral	1.009
BRCA1	P38398-1.2	N1647K	Neutral	1.137
BRCA1	P38398-1.2	N1647L	Neutral	1.009
BRCA1	P38398-1.2	N1647M	Neutral	1.052
BRCA1	P38398-1.2	N1647P	Neutral	1.052
BRCA1	P38398-1.2	N1647Q	Neutral	1.137
BRCA1	P38398-1.2	N1647R	Neutral	1.137
BRCA1	P38398-1.2	N1647S	Neutral	1.179
BRCA1	P38398-1.2	N1647T	Neutral	1.137
BRCA1	P38398-1.2	N1647V	Neutral	1.009
BRCA1	P38398-1.2	N1647W	Neutral	0.967
BRCA1	P38398-1.2	N1647Y	Neutral	1.052
BRCA1	P38398-1.2	K1648A	Neutral	1.149
BRCA1	P38398-1.2	K1648C	Neutral	1.064
BRCA1	P38398-1.2	K1648D	Neutral	1.149
BRCA1	P38398-1.2	K1648E	Neutral	1.234
BRCA1	P38398-1.2	K1648F	Neutral	1.064
BRCA1	P38398-1.2	K1648G	Neutral	1.106
BRCA1	P38398-1.2	K1648H	Neutral	1.149
BRCA1	P38398-1.2	K1648I	Neutral	1.064
BRCA1	P38398-1.2	K1648L	Neutral	1.106
BRCA1	P38398-1.2	K1648M	Neutral	1.149
BRCA1	P38398-1.2	K1648N	Neutral	1.192
BRCA1	P38398-1.2	K1648P	Neutral	1.149
BRCA1	P38398-1.2	K1648Q	Neutral	1.234
BRCA1	P38398-1.2	K1648R	Neutral	1.277
BRCA1	P38398-1.2	K1648S	Neutral	1.192
BRCA1	P38398-1.2	K1648T	Neutral	1.149
BRCA1	P38398-1.2	K1648V	Neutral	1.106
BRCA1	P38398-1.2	K1648W	Neutral	1.064
BRCA1	P38398-1.2	K1648Y	Neutral	1.106
BRCA1	P38398-1.2	R1649A	Neutral	0.99
BRCA1	P38398-1.2	R1649C	Neutral	0.905
BRCA1	P38398-1.2	R1649D	Neutral	0.947
BRCA1	P38398-1.2	R1649E	Neutral	1.033
BRCA1	P38398-1.2	R1649F	Neutral	0.905
BRCA1	P38398-1.2	R1649G	Neutral	0.947
BRCA1	P38398-1.2	R1649H	Neutral	1.033
BRCA1	P38398-1.2	R1649I	Neutral	0.905
BRCA1	P38398-1.2	R1649K	Neutral	1.118
BRCA1	P38398-1.2	R1649L	Neutral	0.947
BRCA1	P38398-1.2	R1649M	Neutral	0.99
BRCA1	P38398-1.2	R1649N	Neutral	1.033
BRCA1	P38398-1.2	R1649P	Neutral	0.947
BRCA1	P38398-1.2	R1649Q	Neutral	1.075
BRCA1	P38398-1.2	R1649S	Neutral	0.99
BRCA1	P38398-1.2	R1649T	Neutral	0.99
BRCA1	P38398-1.2	R1649V	Neutral	0.905
BRCA1	P38398-1.2	R1649W	Neutral	0.905
BRCA1	P38398-1.2	R1649Y	Neutral	0.947
BRCA1	P38398-1.2	M1650A	Pathogenic	0.53
BRCA1	P38398-1.2	M1650C	Pathogenic	0.53
BRCA1	P38398-1.2	M1650D	Pathogenic	0.445
BRCA1	P38398-1.2	M1650E	Pathogenic	0.487
BRCA1	P38398-1.2	M1650F	Neutral	0.573
BRCA1	P38398-1.2	M1650G	Pathogenic	0.445
BRCA1	P38398-1.2	M1650H	Pathogenic	0.487
BRCA1	P38398-1.2	M1650I	Neutral	0.615
BRCA1	P38398-1.2	M1650K	Pathogenic	0.53
BRCA1	P38398-1.2	M1650L	Neutral	0.658
BRCA1	P38398-1.2	M1650N	Pathogenic	0.487
BRCA1	P38398-1.2	M1650P	Pathogenic	0.487
BRCA1	P38398-1.2	M1650Q	Neutral	0.573
BRCA1	P38398-1.2	M1650R	Pathogenic	0.53
BRCA1	P38398-1.2	M1650S	Pathogenic	0.53
BRCA1	P38398-1.2	M1650T	Pathogenic	0.53
BRCA1	P38398-1.2	M1650V	Neutral	0.615
BRCA1	P38398-1.2	M1650W	Pathogenic	0.53
BRCA1	P38398-1.2	M1650Y	Pathogenic	0.53
BRCA1	P38398-1.2	S1651A	Neutral	0.907
BRCA1	P38398-1.2	S1651C	Neutral	0.822
BRCA1	P38398-1.2	S1651D	Neutral	0.864
BRCA1	P38398-1.2	S1651E	Neutral	0.864
BRCA1	P38398-1.2	S1651F	Neutral	0.779
BRCA1	P38398-1.2	S1651G	Neutral	0.864
BRCA1	P38398-1.2	S1651H	Neutral	0.822
BRCA1	P38398-1.2	S1651I	Neutral	0.779
BRCA1	P38398-1.2	S1651K	Neutral	0.864
BRCA1	P38398-1.2	S1651L	Neutral	0.779
BRCA1	P38398-1.2	S1651M	Neutral	0.822
BRCA1	P38398-1.2	S1651N	Neutral	0.907
BRCA1	P38398-1.2	S1651P	Neutral	0.822
BRCA1	P38398-1.2	S1651Q	Neutral	0.864
BRCA1	P38398-1.2	S1651R	Neutral	0.822
BRCA1	P38398-1.2	S1651T	Neutral	0.907
BRCA1	P38398-1.2	S1651V	Neutral	0.779
BRCA1	P38398-1.2	S1651W	Neutral	0.737
BRCA1	P38398-1.2	S1651Y	Neutral	0.779
BRCA1	P38398-1.2	M1652A	Neutral	0.645
BRCA1	P38398-1.2	M1652C	Neutral	0.645
BRCA1	P38398-1.2	M1652D	Neutral	0.56
BRCA1	P38398-1.2	M1652E	Neutral	0.602
BRCA1	P38398-1.2	M1652F	Neutral	0.687
BRCA1	P38398-1.2	M1652G	Neutral	0.56
BRCA1	P38398-1.2	M1652H	Neutral	0.602
BRCA1	P38398-1.2	M1652I	Neutral	0.73
BRCA1	P38398-1.2	M1652K	Neutral	0.645
BRCA1	P38398-1.2	M1652L	Neutral	0.773
BRCA1	P38398-1.2	M1652N	Neutral	0.602
BRCA1	P38398-1.2	M1652P	Neutral	0.602
BRCA1	P38398-1.2	M1652Q	Neutral	0.687
BRCA1	P38398-1.2	M1652R	Neutral	0.645
BRCA1	P38398-1.2	M1652S	Neutral	0.645
BRCA1	P38398-1.2	M1652T	Neutral	0.645
BRCA1	P38398-1.2	M1652V	Neutral	0.73
BRCA1	P38398-1.2	M1652W	Neutral	0.645
BRCA1	P38398-1.2	M1652Y	Neutral	0.645
BRCA1	P38398-1.2	V1653A	Neutral	0.708
BRCA1	P38398-1.2	V1653C	Neutral	0.665
BRCA1	P38398-1.2	V1653D	Neutral	0.58
BRCA1	P38398-1.2	V1653E	Neutral	0.623
BRCA1	P38398-1.2	V1653F	Neutral	0.665
BRCA1	P38398-1.2	V1653G	Neutral	0.58
BRCA1	P38398-1.2	V1653H	Neutral	0.58
BRCA1	P38398-1.2	V1653I	Neutral	0.836
BRCA1	P38398-1.2	V1653K	Neutral	0.623
BRCA1	P38398-1.2	V1653L	Neutral	0.751
BRCA1	P38398-1.2	V1653M	Neutral	0.751
BRCA1	P38398-1.2	V1653N	Neutral	0.58
BRCA1	P38398-1.2	V1653P	Neutral	0.623
BRCA1	P38398-1.2	V1653Q	Neutral	0.623
BRCA1	P38398-1.2	V1653R	Neutral	0.58
BRCA1	P38398-1.2	V1653S	Neutral	0.623
BRCA1	P38398-1.2	V1653T	Neutral	0.708
BRCA1	P38398-1.2	V1653W	Neutral	0.58
BRCA1	P38398-1.2	V1653Y	Neutral	0.665
BRCA1	P38398-1.2	V1654A	Neutral	1.048
BRCA1	P38398-1.2	V1654C	Neutral	1.006
BRCA1	P38398-1.2	V1654D	Neutral	0.921
BRCA1	P38398-1.2	V1654E	Neutral	0.963
BRCA1	P38398-1.2	V1654F	Neutral	1.006
BRCA1	P38398-1.2	V1654G	Neutral	0.921
BRCA1	P38398-1.2	V1654H	Neutral	0.921
BRCA1	P38398-1.2	V1654I	Neutral	1.176
BRCA1	P38398-1.2	V1654K	Neutral	0.963
BRCA1	P38398-1.2	V1654L	Neutral	1.091
BRCA1	P38398-1.2	V1654M	Neutral	1.091
BRCA1	P38398-1.2	V1654N	Neutral	0.921
BRCA1	P38398-1.2	V1654P	Neutral	0.963
BRCA1	P38398-1.2	V1654Q	Neutral	0.963
BRCA1	P38398-1.2	V1654R	Neutral	0.921
BRCA1	P38398-1.2	V1654S	Neutral	0.963
BRCA1	P38398-1.2	V1654T	Neutral	1.048
BRCA1	P38398-1.2	V1654W	Neutral	0.921
BRCA1	P38398-1.2	V1654Y	Neutral	1.006
BRCA1	P38398-1.2	S1655A	Neutral	0.96
BRCA1	P38398-1.2	S1655C	Neutral	0.875
BRCA1	P38398-1.2	S1655D	Neutral	0.918
BRCA1	P38398-1.2	S1655E	Neutral	0.918
BRCA1	P38398-1.2	S1655F	Neutral	0.833
BRCA1	P38398-1.2	S1655G	Neutral	0.918
BRCA1	P38398-1.2	S1655H	Neutral	0.875
BRCA1	P38398-1.2	S1655I	Neutral	0.833
BRCA1	P38398-1.2	S1655K	Neutral	0.918
BRCA1	P38398-1.2	S1655L	Neutral	0.833
BRCA1	P38398-1.2	S1655M	Neutral	0.875
BRCA1	P38398-1.2	S1655N	Neutral	0.96
BRCA1	P38398-1.2	S1655P	Neutral	0.875
BRCA1	P38398-1.2	S1655Q	Neutral	0.918
BRCA1	P38398-1.2	S1655R	Neutral	0.875
BRCA1	P38398-1.2	S1655T	Neutral	0.96
BRCA1	P38398-1.2	S1655V	Neutral	0.833
BRCA1	P38398-1.2	S1655W	Neutral	0.79
BRCA1	P38398-1.2	S1655Y	Neutral	0.833
BRCA1	P38398-1.2	G1656A	Pathogenic	0.497
BRCA1	P38398-1.2	G1656C	Pathogenic	0.369
BRCA1	P38398-1.2	G1656D	Pathogenic	0.455
BRCA1	P38398-1.2	G1656E	Pathogenic	0.412
BRCA1	P38398-1.2	G1656F	Pathogenic	0.369
BRCA1	P38398-1.2	G1656H	Pathogenic	0.412
BRCA1	P38398-1.2	G1656I	Pathogenic	0.327
BRCA1	P38398-1.2	G1656K	Pathogenic	0.412
BRCA1	P38398-1.2	G1656L	Pathogenic	0.327
BRCA1	P38398-1.2	G1656M	Pathogenic	0.369
BRCA1	P38398-1.2	G1656N	Pathogenic	0.497
BRCA1	P38398-1.2	G1656P	Pathogenic	0.412
BRCA1	P38398-1.2	G1656Q	Pathogenic	0.412
BRCA1	P38398-1.2	G1656R	Pathogenic	0.412
BRCA1	P38398-1.2	G1656S	Pathogenic	0.497
BRCA1	P38398-1.2	G1656T	Pathogenic	0.412
BRCA1	P38398-1.2	G1656V	Pathogenic	0.369
BRCA1	P38398-1.2	G1656W	Pathogenic	0.412
BRCA1	P38398-1.2	G1656Y	Pathogenic	0.369
BRCA1	P38398-1.2	L1657A	Neutral	0.582
BRCA1	P38398-1.2	L1657C	Neutral	0.582
BRCA1	P38398-1.2	L1657D	Pathogenic	0.455
BRCA1	P38398-1.2	L1657E	Pathogenic	0.497
BRCA1	P38398-1.2	L1657F	Neutral	0.625
BRCA1	P38398-1.2	L1657G	Pathogenic	0.455
BRCA1	P38398-1.2	L1657H	Pathogenic	0.497
BRCA1	P38398-1.2	L1657I	Neutral	0.71
BRCA1	P38398-1.2	L1657K	Neutral	0.54
BRCA1	P38398-1.2	L1657M	Neutral	0.71
BRCA1	P38398-1.2	L1657N	Pathogenic	0.497
BRCA1	P38398-1.2	L1657P	Pathogenic	0.497
BRCA1	P38398-1.2	L1657Q	Neutral	0.54
BRCA1	P38398-1.2	L1657R	Neutral	0.54
BRCA1	P38398-1.2	L1657S	Neutral	0.54
BRCA1	P38398-1.2	L1657T	Neutral	0.582
BRCA1	P38398-1.2	L1657V	Neutral	0.668
BRCA1	P38398-1.2	L1657W	Neutral	0.54
BRCA1	P38398-1.2	L1657Y	Neutral	0.582
BRCA1	P38398-1.2	T1658A	Neutral	0.915
BRCA1	P38398-1.2	T1658C	Neutral	0.872
BRCA1	P38398-1.2	T1658D	Neutral	0.872
BRCA1	P38398-1.2	T1658E	Neutral	0.872
BRCA1	P38398-1.2	T1658F	Neutral	0.829
BRCA1	P38398-1.2	T1658G	Neutral	0.829
BRCA1	P38398-1.2	T1658H	Neutral	0.829
BRCA1	P38398-1.2	T1658I	Neutral	0.872
BRCA1	P38398-1.2	T1658K	Neutral	0.872
BRCA1	P38398-1.2	T1658L	Neutral	0.872
BRCA1	P38398-1.2	T1658M	Neutral	0.872
BRCA1	P38398-1.2	T1658N	Neutral	0.915
BRCA1	P38398-1.2	T1658P	Neutral	0.872
BRCA1	P38398-1.2	T1658Q	Neutral	0.872
BRCA1	P38398-1.2	T1658R	Neutral	0.872
BRCA1	P38398-1.2	T1658S	Neutral	0.957
BRCA1	P38398-1.2	T1658V	Neutral	0.915
BRCA1	P38398-1.2	T1658W	Neutral	0.829
BRCA1	P38398-1.2	T1658Y	Neutral	0.829
BRCA1	P38398-1.2	P1659A	Neutral	0.811
BRCA1	P38398-1.2	P1659C	Neutral	0.725
BRCA1	P38398-1.2	P1659D	Neutral	0.811
BRCA1	P38398-1.2	P1659E	Neutral	0.811
BRCA1	P38398-1.2	P1659F	Neutral	0.683
BRCA1	P38398-1.2	P1659G	Neutral	0.768
BRCA1	P38398-1.2	P1659H	Neutral	0.768
BRCA1	P38398-1.2	P1659I	Neutral	0.725
BRCA1	P38398-1.2	P1659K	Neutral	0.811
BRCA1	P38398-1.2	P1659L	Neutral	0.725
BRCA1	P38398-1.2	P1659M	Neutral	0.768
BRCA1	P38398-1.2	P1659N	Neutral	0.768
BRCA1	P38398-1.2	P1659Q	Neutral	0.811
BRCA1	P38398-1.2	P1659R	Neutral	0.768
BRCA1	P38398-1.2	P1659S	Neutral	0.811
BRCA1	P38398-1.2	P1659T	Neutral	0.811
BRCA1	P38398-1.2	P1659V	Neutral	0.768
BRCA1	P38398-1.2	P1659W	Neutral	0.683
BRCA1	P38398-1.2	P1659Y	Neutral	0.725
BRCA1	P38398-1.2	E1660A	Neutral	1.33
BRCA1	P38398-1.2	E1660C	Neutral	1.203
BRCA1	P38398-1.2	E1660D	Neutral	1.458
BRCA1	P38398-1.2	E1660F	Neutral	1.245
BRCA1	P38398-1.2	E1660G	Neutral	1.288
BRCA1	P38398-1.2	E1660H	Neutral	1.373
BRCA1	P38398-1.2	E1660I	Neutral	1.245
BRCA1	P38398-1.2	E1660K	Neutral	1.416
BRCA1	P38398-1.2	E1660L	Neutral	1.245
BRCA1	P38398-1.2	E1660M	Neutral	1.288
BRCA1	P38398-1.2	E1660N	Neutral	1.373
BRCA1	P38398-1.2	E1660P	Neutral	1.33
BRCA1	P38398-1.2	E1660Q	Neutral	1.458
BRCA1	P38398-1.2	E1660R	Neutral	1.373
BRCA1	P38398-1.2	E1660S	Neutral	1.373
BRCA1	P38398-1.2	E1660T	Neutral	1.33
BRCA1	P38398-1.2	E1660V	Neutral	1.288
BRCA1	P38398-1.2	E1660W	Neutral	1.245
BRCA1	P38398-1.2	E1660Y	Neutral	1.288
BRCA1	P38398-1.2	E1661A	Neutral	0.766
BRCA1	P38398-1.2	E1661C	Neutral	0.638
BRCA1	P38398-1.2	E1661D	Neutral	0.894
BRCA1	P38398-1.2	E1661F	Neutral	0.681
BRCA1	P38398-1.2	E1661G	Neutral	0.723
BRCA1	P38398-1.2	E1661H	Neutral	0.808
BRCA1	P38398-1.2	E1661I	Neutral	0.681
BRCA1	P38398-1.2	E1661K	Neutral	0.851
BRCA1	P38398-1.2	E1661L	Neutral	0.681
BRCA1	P38398-1.2	E1661M	Neutral	0.723
BRCA1	P38398-1.2	E1661N	Neutral	0.808
BRCA1	P38398-1.2	E1661P	Neutral	0.766
BRCA1	P38398-1.2	E1661Q	Neutral	0.894
BRCA1	P38398-1.2	E1661R	Neutral	0.808
BRCA1	P38398-1.2	E1661S	Neutral	0.808
BRCA1	P38398-1.2	E1661T	Neutral	0.766
BRCA1	P38398-1.2	E1661V	Neutral	0.723
BRCA1	P38398-1.2	E1661W	Neutral	0.681
BRCA1	P38398-1.2	E1661Y	Neutral	0.723
BRCA1	P38398-1.2	F1662A	Neutral	0.928
BRCA1	P38398-1.2	F1662C	Neutral	0.928
BRCA1	P38398-1.2	F1662D	Neutral	0.885
BRCA1	P38398-1.2	F1662E	Neutral	0.885
BRCA1	P38398-1.2	F1662G	Neutral	0.885
BRCA1	P38398-1.2	F1662H	Neutral	0.97
BRCA1	P38398-1.2	F1662I	Neutral	1.013
BRCA1	P38398-1.2	F1662K	Neutral	0.885
BRCA1	P38398-1.2	F1662L	Neutral	1.013
BRCA1	P38398-1.2	F1662M	Neutral	1.013
BRCA1	P38398-1.2	F1662N	Neutral	0.885
BRCA1	P38398-1.2	F1662P	Neutral	0.842
BRCA1	P38398-1.2	F1662Q	Neutral	0.885
BRCA1	P38398-1.2	F1662R	Neutral	0.885
BRCA1	P38398-1.2	F1662S	Neutral	0.928
BRCA1	P38398-1.2	F1662T	Neutral	0.928
BRCA1	P38398-1.2	F1662V	Neutral	0.97
BRCA1	P38398-1.2	F1662W	Neutral	1.055
BRCA1	P38398-1.2	F1662Y	Neutral	1.14
BRCA1	P38398-1.2	M1663A	Neutral	0.644
BRCA1	P38398-1.2	M1663C	Neutral	0.644
BRCA1	P38398-1.2	M1663D	Neutral	0.559
BRCA1	P38398-1.2	M1663E	Neutral	0.601
BRCA1	P38398-1.2	M1663F	Neutral	0.687
BRCA1	P38398-1.2	M1663G	Neutral	0.559
BRCA1	P38398-1.2	M1663H	Neutral	0.601
BRCA1	P38398-1.2	M1663I	Neutral	0.729
BRCA1	P38398-1.2	M1663K	Neutral	0.644
BRCA1	P38398-1.2	M1663L	Neutral	0.772
BRCA1	P38398-1.2	M1663N	Neutral	0.601
BRCA1	P38398-1.2	M1663P	Neutral	0.601
BRCA1	P38398-1.2	M1663Q	Neutral	0.687
BRCA1	P38398-1.2	M1663R	Neutral	0.644
BRCA1	P38398-1.2	M1663S	Neutral	0.644
BRCA1	P38398-1.2	M1663T	Neutral	0.644
BRCA1	P38398-1.2	M1663V	Neutral	0.729
BRCA1	P38398-1.2	M1663W	Neutral	0.644
BRCA1	P38398-1.2	M1663Y	Neutral	0.644
BRCA1	P38398-1.2	L1664A	Neutral	1.019
BRCA1	P38398-1.2	L1664C	Neutral	1.019
BRCA1	P38398-1.2	L1664D	Neutral	0.891
BRCA1	P38398-1.2	L1664E	Neutral	0.934
BRCA1	P38398-1.2	L1664F	Neutral	1.062
BRCA1	P38398-1.2	L1664G	Neutral	0.891
BRCA1	P38398-1.2	L1664H	Neutral	0.934
BRCA1	P38398-1.2	L1664I	Neutral	1.147
BRCA1	P38398-1.2	L1664K	Neutral	0.977
BRCA1	P38398-1.2	L1664M	Neutral	1.147
BRCA1	P38398-1.2	L1664N	Neutral	0.934
BRCA1	P38398-1.2	L1664P	Neutral	0.934
BRCA1	P38398-1.2	L1664Q	Neutral	0.977
BRCA1	P38398-1.2	L1664R	Neutral	0.977
BRCA1	P38398-1.2	L1664S	Neutral	0.977
BRCA1	P38398-1.2	L1664T	Neutral	1.019
BRCA1	P38398-1.2	L1664V	Neutral	1.104
BRCA1	P38398-1.2	L1664W	Neutral	0.977
BRCA1	P38398-1.2	L1664Y	Neutral	1.019
BRCA1	P38398-1.2	V1665A	Neutral	0.533
BRCA1	P38398-1.2	V1665C	Pathogenic	0.491
BRCA1	P38398-1.2	V1665D	Pathogenic	0.406
BRCA1	P38398-1.2	V1665E	Pathogenic	0.448
BRCA1	P38398-1.2	V1665F	Pathogenic	0.491
BRCA1	P38398-1.2	V1665G	Pathogenic	0.406
BRCA1	P38398-1.2	V1665H	Pathogenic	0.406
BRCA1	P38398-1.2	V1665I	Neutral	0.661
BRCA1	P38398-1.2	V1665K	Pathogenic	0.448
BRCA1	P38398-1.2	V1665L	Neutral	0.576
BRCA1	P38398-1.2	V1665M	Neutral	0.576
BRCA1	P38398-1.2	V1665N	Pathogenic	0.406
BRCA1	P38398-1.2	V1665P	Pathogenic	0.448
BRCA1	P38398-1.2	V1665Q	Pathogenic	0.448
BRCA1	P38398-1.2	V1665R	Pathogenic	0.406
BRCA1	P38398-1.2	V1665S	Pathogenic	0.448
BRCA1	P38398-1.2	V1665T	Neutral	0.533
BRCA1	P38398-1.2	V1665W	Pathogenic	0.406
BRCA1	P38398-1.2	V1665Y	Pathogenic	0.491
BRCA1	P38398-1.2	Y1666A	Neutral	0.695
BRCA1	P38398-1.2	Y1666C	Neutral	0.695
BRCA1	P38398-1.2	Y1666D	Neutral	0.652
BRCA1	P38398-1.2	Y1666E	Neutral	0.695
BRCA1	P38398-1.2	Y1666F	Neutral	0.907
BRCA1	P38398-1.2	Y1666G	Neutral	0.652
BRCA1	P38398-1.2	Y1666H	Neutral	0.865
BRCA1	P38398-1.2	Y1666I	Neutral	0.737
BRCA1	P38398-1.2	Y1666K	Neutral	0.695
BRCA1	P38398-1.2	Y1666L	Neutral	0.737
BRCA1	P38398-1.2	Y1666M	Neutral	0.737
BRCA1	P38398-1.2	Y1666N	Neutral	0.695
BRCA1	P38398-1.2	Y1666P	Neutral	0.652
BRCA1	P38398-1.2	Y1666Q	Neutral	0.737
BRCA1	P38398-1.2	Y1666R	Neutral	0.695
BRCA1	P38398-1.2	Y1666S	Neutral	0.695
BRCA1	P38398-1.2	Y1666T	Neutral	0.695
BRCA1	P38398-1.2	Y1666V	Neutral	0.737
BRCA1	P38398-1.2	Y1666W	Neutral	0.865
BRCA1	P38398-1.2	K1667A	Neutral	0.847
BRCA1	P38398-1.2	K1667C	Neutral	0.761
BRCA1	P38398-1.2	K1667D	Neutral	0.847
BRCA1	P38398-1.2	K1667E	Neutral	0.932
BRCA1	P38398-1.2	K1667F	Neutral	0.761
BRCA1	P38398-1.2	K1667G	Neutral	0.804
BRCA1	P38398-1.2	K1667H	Neutral	0.847
BRCA1	P38398-1.2	K1667I	Neutral	0.761
BRCA1	P38398-1.2	K1667L	Neutral	0.804
BRCA1	P38398-1.2	K1667M	Neutral	0.847
BRCA1	P38398-1.2	K1667N	Neutral	0.889
BRCA1	P38398-1.2	K1667P	Neutral	0.847
BRCA1	P38398-1.2	K1667Q	Neutral	0.932
BRCA1	P38398-1.2	K1667R	Neutral	0.974
BRCA1	P38398-1.2	K1667S	Neutral	0.889
BRCA1	P38398-1.2	K1667T	Neutral	0.847
BRCA1	P38398-1.2	K1667V	Neutral	0.804
BRCA1	P38398-1.2	K1667W	Neutral	0.761
BRCA1	P38398-1.2	K1667Y	Neutral	0.804
BRCA1	P38398-1.2	F1668A	Pathogenic	0.406
BRCA1	P38398-1.2	F1668C	Pathogenic	0.406
BRCA1	P38398-1.2	F1668D	Pathogenic	0.363
BRCA1	P38398-1.2	F1668E	Pathogenic	0.363
BRCA1	P38398-1.2	F1668G	Pathogenic	0.363
BRCA1	P38398-1.2	F1668H	Pathogenic	0.449
BRCA1	P38398-1.2	F1668I	Pathogenic	0.491
BRCA1	P38398-1.2	F1668K	Pathogenic	0.363
BRCA1	P38398-1.2	F1668L	Pathogenic	0.491
BRCA1	P38398-1.2	F1668M	Pathogenic	0.491
BRCA1	P38398-1.2	F1668N	Pathogenic	0.363
BRCA1	P38398-1.2	F1668P	Pathogenic	0.321
BRCA1	P38398-1.2	F1668Q	Pathogenic	0.363
BRCA1	P38398-1.2	F1668R	Pathogenic	0.363
BRCA1	P38398-1.2	F1668S	Pathogenic	0.406
BRCA1	P38398-1.2	F1668T	Pathogenic	0.406
BRCA1	P38398-1.2	F1668V	Pathogenic	0.449
BRCA1	P38398-1.2	F1668W	Neutral	0.534
BRCA1	P38398-1.2	F1668Y	Neutral	0.619
BRCA1	P38398-1.2	A1669C	Neutral	0.782
BRCA1	P38398-1.2	A1669D	Neutral	0.697
BRCA1	P38398-1.2	A1669E	Neutral	0.74
BRCA1	P38398-1.2	A1669F	Neutral	0.697
BRCA1	P38398-1.2	A1669G	Neutral	0.782
BRCA1	P38398-1.2	A1669H	Neutral	0.697
BRCA1	P38398-1.2	A1669I	Neutral	0.74
BRCA1	P38398-1.2	A1669K	Neutral	0.74
BRCA1	P38398-1.2	A1669L	Neutral	0.74
BRCA1	P38398-1.2	A1669M	Neutral	0.74
BRCA1	P38398-1.2	A1669N	Neutral	0.697
BRCA1	P38398-1.2	A1669P	Neutral	0.74
BRCA1	P38398-1.2	A1669Q	Neutral	0.74
BRCA1	P38398-1.2	A1669R	Neutral	0.74
BRCA1	P38398-1.2	A1669S	Neutral	0.825
BRCA1	P38398-1.2	A1669T	Neutral	0.782
BRCA1	P38398-1.2	A1669V	Neutral	0.782
BRCA1	P38398-1.2	A1669W	Neutral	0.655
BRCA1	P38398-1.2	A1669Y	Neutral	0.697
BRCA1	P38398-1.2	R1670A	Neutral	0.869
BRCA1	P38398-1.2	R1670C	Neutral	0.784
BRCA1	P38398-1.2	R1670D	Neutral	0.826
BRCA1	P38398-1.2	R1670E	Neutral	0.911
BRCA1	P38398-1.2	R1670F	Neutral	0.784
BRCA1	P38398-1.2	R1670G	Neutral	0.826
BRCA1	P38398-1.2	R1670H	Neutral	0.911
BRCA1	P38398-1.2	R1670I	Neutral	0.784
BRCA1	P38398-1.2	R1670K	Neutral	0.996
BRCA1	P38398-1.2	R1670L	Neutral	0.826
BRCA1	P38398-1.2	R1670M	Neutral	0.869
BRCA1	P38398-1.2	R1670N	Neutral	0.911
BRCA1	P38398-1.2	R1670P	Neutral	0.826
BRCA1	P38398-1.2	R1670Q	Neutral	0.954
BRCA1	P38398-1.2	R1670S	Neutral	0.869
BRCA1	P38398-1.2	R1670T	Neutral	0.869
BRCA1	P38398-1.2	R1670V	Neutral	0.784
BRCA1	P38398-1.2	R1670W	Neutral	0.784
BRCA1	P38398-1.2	R1670Y	Neutral	0.826
BRCA1	P38398-1.2	K1671A	Neutral	0.998
BRCA1	P38398-1.2	K1671C	Neutral	0.913
BRCA1	P38398-1.2	K1671D	Neutral	0.998
BRCA1	P38398-1.2	K1671E	Neutral	1.083
BRCA1	P38398-1.2	K1671F	Neutral	0.913
BRCA1	P38398-1.2	K1671G	Neutral	0.955
BRCA1	P38398-1.2	K1671H	Neutral	0.998
BRCA1	P38398-1.2	K1671I	Neutral	0.913
BRCA1	P38398-1.2	K1671L	Neutral	0.955
BRCA1	P38398-1.2	K1671M	Neutral	0.998
BRCA1	P38398-1.2	K1671N	Neutral	1.041
BRCA1	P38398-1.2	K1671P	Neutral	0.998
BRCA1	P38398-1.2	K1671Q	Neutral	1.083
BRCA1	P38398-1.2	K1671R	Neutral	1.126
BRCA1	P38398-1.2	K1671S	Neutral	1.041
BRCA1	P38398-1.2	K1671T	Neutral	0.998
BRCA1	P38398-1.2	K1671V	Neutral	0.955
BRCA1	P38398-1.2	K1671W	Neutral	0.913
BRCA1	P38398-1.2	K1671Y	Neutral	0.955
BRCA1	P38398-1.2	H1672A	Neutral	0.843
BRCA1	P38398-1.2	H1672C	Neutral	0.8
BRCA1	P38398-1.2	H1672D	Neutral	0.885
BRCA1	P38398-1.2	H1672E	Neutral	0.928
BRCA1	P38398-1.2	H1672F	Neutral	0.885
BRCA1	P38398-1.2	H1672G	Neutral	0.843
BRCA1	P38398-1.2	H1672I	Neutral	0.8
BRCA1	P38398-1.2	H1672K	Neutral	0.885
BRCA1	P38398-1.2	H1672L	Neutral	0.8
BRCA1	P38398-1.2	H1672M	Neutral	0.843
BRCA1	P38398-1.2	H1672N	Neutral	0.971
BRCA1	P38398-1.2	H1672P	Neutral	0.843
BRCA1	P38398-1.2	H1672Q	Neutral	0.928
BRCA1	P38398-1.2	H1672R	Neutral	0.928
BRCA1	P38398-1.2	H1672S	Neutral	0.885
BRCA1	P38398-1.2	H1672T	Neutral	0.843
BRCA1	P38398-1.2	H1672V	Neutral	0.8
BRCA1	P38398-1.2	H1672W	Neutral	0.843
BRCA1	P38398-1.2	H1672Y	Neutral	1.013
BRCA1	P38398-1.2	H1673A	Neutral	0.747
BRCA1	P38398-1.2	H1673C	Neutral	0.704
BRCA1	P38398-1.2	H1673D	Neutral	0.789
BRCA1	P38398-1.2	H1673E	Neutral	0.832
BRCA1	P38398-1.2	H1673F	Neutral	0.789
BRCA1	P38398-1.2	H1673G	Neutral	0.747
BRCA1	P38398-1.2	H1673I	Neutral	0.704
BRCA1	P38398-1.2	H1673K	Neutral	0.789
BRCA1	P38398-1.2	H1673L	Neutral	0.704
BRCA1	P38398-1.2	H1673M	Neutral	0.747
BRCA1	P38398-1.2	H1673N	Neutral	0.874
BRCA1	P38398-1.2	H1673P	Neutral	0.747
BRCA1	P38398-1.2	H1673Q	Neutral	0.832
BRCA1	P38398-1.2	H1673R	Neutral	0.832
BRCA1	P38398-1.2	H1673S	Neutral	0.789
BRCA1	P38398-1.2	H1673T	Neutral	0.747
BRCA1	P38398-1.2	H1673V	Neutral	0.704
BRCA1	P38398-1.2	H1673W	Neutral	0.747
BRCA1	P38398-1.2	H1673Y	Neutral	0.917
BRCA1	P38398-1.2	I1674A	Neutral	1.044
BRCA1	P38398-1.2	I1674C	Neutral	1.044
BRCA1	P38398-1.2	I1674D	Neutral	0.959
BRCA1	P38398-1.2	I1674E	Neutral	0.959
BRCA1	P38398-1.2	I1674F	Neutral	1.087
BRCA1	P38398-1.2	I1674G	Neutral	0.917
BRCA1	P38398-1.2	I1674H	Neutral	0.959
BRCA1	P38398-1.2	I1674K	Neutral	0.959
BRCA1	P38398-1.2	I1674L	Neutral	1.172
BRCA1	P38398-1.2	I1674M	Neutral	1.129
BRCA1	P38398-1.2	I1674N	Neutral	0.959
BRCA1	P38398-1.2	I1674P	Neutral	0.959
BRCA1	P38398-1.2	I1674Q	Neutral	0.959
BRCA1	P38398-1.2	I1674R	Neutral	0.959
BRCA1	P38398-1.2	I1674S	Neutral	1.002
BRCA1	P38398-1.2	I1674T	Neutral	1.044
BRCA1	P38398-1.2	I1674V	Neutral	1.215
BRCA1	P38398-1.2	I1674W	Neutral	0.959
BRCA1	P38398-1.2	I1674Y	Neutral	1.044
BRCA1	P38398-1.2	T1675A	Neutral	0.97
BRCA1	P38398-1.2	T1675C	Neutral	0.928
BRCA1	P38398-1.2	T1675D	Neutral	0.928
BRCA1	P38398-1.2	T1675E	Neutral	0.928
BRCA1	P38398-1.2	T1675F	Neutral	0.885
BRCA1	P38398-1.2	T1675G	Neutral	0.885
BRCA1	P38398-1.2	T1675H	Neutral	0.885
BRCA1	P38398-1.2	T1675I	Neutral	0.928
BRCA1	P38398-1.2	T1675K	Neutral	0.928
BRCA1	P38398-1.2	T1675L	Neutral	0.928
BRCA1	P38398-1.2	T1675M	Neutral	0.928
BRCA1	P38398-1.2	T1675N	Neutral	0.97
BRCA1	P38398-1.2	T1675P	Neutral	0.928
BRCA1	P38398-1.2	T1675Q	Neutral	0.928
BRCA1	P38398-1.2	T1675R	Neutral	0.928
BRCA1	P38398-1.2	T1675S	Neutral	1.013
BRCA1	P38398-1.2	T1675V	Neutral	0.97
BRCA1	P38398-1.2	T1675W	Neutral	0.885
BRCA1	P38398-1.2	T1675Y	Neutral	0.885
BRCA1	P38398-1.2	L1676A	Neutral	0.965
BRCA1	P38398-1.2	L1676C	Neutral	0.965
BRCA1	P38398-1.2	L1676D	Neutral	0.837
BRCA1	P38398-1.2	L1676E	Neutral	0.88
BRCA1	P38398-1.2	L1676F	Neutral	1.008
BRCA1	P38398-1.2	L1676G	Neutral	0.837
BRCA1	P38398-1.2	L1676H	Neutral	0.88
BRCA1	P38398-1.2	L1676I	Neutral	1.093
BRCA1	P38398-1.2	L1676K	Neutral	0.922
BRCA1	P38398-1.2	L1676M	Neutral	1.093
BRCA1	P38398-1.2	L1676N	Neutral	0.88
BRCA1	P38398-1.2	L1676P	Neutral	0.88
BRCA1	P38398-1.2	L1676Q	Neutral	0.922
BRCA1	P38398-1.2	L1676R	Neutral	0.922
BRCA1	P38398-1.2	L1676S	Neutral	0.922
BRCA1	P38398-1.2	L1676T	Neutral	0.965
BRCA1	P38398-1.2	L1676V	Neutral	1.05
BRCA1	P38398-1.2	L1676W	Neutral	0.922
BRCA1	P38398-1.2	L1676Y	Neutral	0.965
BRCA1	P38398-1.2	T1677A	Neutral	1.041
BRCA1	P38398-1.2	T1677C	Neutral	0.998
BRCA1	P38398-1.2	T1677D	Neutral	0.998
BRCA1	P38398-1.2	T1677E	Neutral	0.998
BRCA1	P38398-1.2	T1677F	Neutral	0.956
BRCA1	P38398-1.2	T1677G	Neutral	0.956
BRCA1	P38398-1.2	T1677H	Neutral	0.956
BRCA1	P38398-1.2	T1677I	Neutral	0.998
BRCA1	P38398-1.2	T1677K	Neutral	0.998
BRCA1	P38398-1.2	T1677L	Neutral	0.998
BRCA1	P38398-1.2	T1677M	Neutral	0.998
BRCA1	P38398-1.2	T1677N	Neutral	1.041
BRCA1	P38398-1.2	T1677P	Neutral	0.998
BRCA1	P38398-1.2	T1677Q	Neutral	0.998
BRCA1	P38398-1.2	T1677R	Neutral	0.998
BRCA1	P38398-1.2	T1677S	Neutral	1.084
BRCA1	P38398-1.2	T1677V	Neutral	1.041
BRCA1	P38398-1.2	T1677W	Neutral	0.956
BRCA1	P38398-1.2	T1677Y	Neutral	0.956
BRCA1	P38398-1.2	N1678A	Neutral	0.874
BRCA1	P38398-1.2	N1678C	Neutral	0.832
BRCA1	P38398-1.2	N1678D	Neutral	1.002
BRCA1	P38398-1.2	N1678E	Neutral	0.959
BRCA1	P38398-1.2	N1678F	Neutral	0.832
BRCA1	P38398-1.2	N1678G	Neutral	0.959
BRCA1	P38398-1.2	N1678H	Neutral	1.002
BRCA1	P38398-1.2	N1678I	Neutral	0.832
BRCA1	P38398-1.2	N1678K	Neutral	0.959
BRCA1	P38398-1.2	N1678L	Neutral	0.832
BRCA1	P38398-1.2	N1678M	Neutral	0.874
BRCA1	P38398-1.2	N1678P	Neutral	0.874
BRCA1	P38398-1.2	N1678Q	Neutral	0.959
BRCA1	P38398-1.2	N1678R	Neutral	0.959
BRCA1	P38398-1.2	N1678S	Neutral	1.002
BRCA1	P38398-1.2	N1678T	Neutral	0.959
BRCA1	P38398-1.2	N1678V	Neutral	0.832
BRCA1	P38398-1.2	N1678W	Neutral	0.789
BRCA1	P38398-1.2	N1678Y	Neutral	0.874
BRCA1	P38398-1.2	L1679A	Neutral	1.158
BRCA1	P38398-1.2	L1679C	Neutral	1.158
BRCA1	P38398-1.2	L1679D	Neutral	1.03
BRCA1	P38398-1.2	L1679E	Neutral	1.072
BRCA1	P38398-1.2	L1679F	Neutral	1.2
BRCA1	P38398-1.2	L1679G	Neutral	1.03
BRCA1	P38398-1.2	L1679H	Neutral	1.072
BRCA1	P38398-1.2	L1679I	Neutral	1.285
BRCA1	P38398-1.2	L1679K	Neutral	1.115
BRCA1	P38398-1.2	L1679M	Neutral	1.285
BRCA1	P38398-1.2	L1679N	Neutral	1.072
BRCA1	P38398-1.2	L1679P	Neutral	1.072
BRCA1	P38398-1.2	L1679Q	Neutral	1.115
BRCA1	P38398-1.2	L1679R	Neutral	1.115
BRCA1	P38398-1.2	L1679S	Neutral	1.115
BRCA1	P38398-1.2	L1679T	Neutral	1.158
BRCA1	P38398-1.2	L1679V	Neutral	1.243
BRCA1	P38398-1.2	L1679W	Neutral	1.115
BRCA1	P38398-1.2	L1679Y	Neutral	1.158
BRCA1	P38398-1.2	I1680A	Neutral	0.68
BRCA1	P38398-1.2	I1680C	Neutral	0.68
BRCA1	P38398-1.2	I1680D	Neutral	0.595
BRCA1	P38398-1.2	I1680E	Neutral	0.595
BRCA1	P38398-1.2	I1680F	Neutral	0.723
BRCA1	P38398-1.2	I1680G	Neutral	0.553
BRCA1	P38398-1.2	I1680H	Neutral	0.595
BRCA1	P38398-1.2	I1680K	Neutral	0.595
BRCA1	P38398-1.2	I1680L	Neutral	0.808
BRCA1	P38398-1.2	I1680M	Neutral	0.765
BRCA1	P38398-1.2	I1680N	Neutral	0.595
BRCA1	P38398-1.2	I1680P	Neutral	0.595
BRCA1	P38398-1.2	I1680Q	Neutral	0.595
BRCA1	P38398-1.2	I1680R	Neutral	0.595
BRCA1	P38398-1.2	I1680S	Neutral	0.638
BRCA1	P38398-1.2	I1680T	Neutral	0.68
BRCA1	P38398-1.2	I1680V	Neutral	0.851
BRCA1	P38398-1.2	I1680W	Neutral	0.595
BRCA1	P38398-1.2	I1680Y	Neutral	0.68
BRCA1	P38398-1.2	T1681A	Neutral	0.847
BRCA1	P38398-1.2	T1681C	Neutral	0.805
BRCA1	P38398-1.2	T1681D	Neutral	0.805
BRCA1	P38398-1.2	T1681E	Neutral	0.805
BRCA1	P38398-1.2	T1681F	Neutral	0.762
BRCA1	P38398-1.2	T1681G	Neutral	0.762
BRCA1	P38398-1.2	T1681H	Neutral	0.762
BRCA1	P38398-1.2	T1681I	Neutral	0.805
BRCA1	P38398-1.2	T1681K	Neutral	0.805
BRCA1	P38398-1.2	T1681L	Neutral	0.805
BRCA1	P38398-1.2	T1681M	Neutral	0.805
BRCA1	P38398-1.2	T1681N	Neutral	0.847
BRCA1	P38398-1.2	T1681P	Neutral	0.805
BRCA1	P38398-1.2	T1681Q	Neutral	0.805
BRCA1	P38398-1.2	T1681R	Neutral	0.805
BRCA1	P38398-1.2	T1681S	Neutral	0.89
BRCA1	P38398-1.2	T1681V	Neutral	0.847
BRCA1	P38398-1.2	T1681W	Neutral	0.762
BRCA1	P38398-1.2	T1681Y	Neutral	0.762
BRCA1	P38398-1.2	E1682A	Neutral	1.093
BRCA1	P38398-1.2	E1682C	Neutral	0.966
BRCA1	P38398-1.2	E1682D	Neutral	1.221
BRCA1	P38398-1.2	E1682F	Neutral	1.008
BRCA1	P38398-1.2	E1682G	Neutral	1.051
BRCA1	P38398-1.2	E1682H	Neutral	1.136
BRCA1	P38398-1.2	E1682I	Neutral	1.008
BRCA1	P38398-1.2	E1682K	Neutral	1.178
BRCA1	P38398-1.2	E1682L	Neutral	1.008
BRCA1	P38398-1.2	E1682M	Neutral	1.051
BRCA1	P38398-1.2	E1682N	Neutral	1.136
BRCA1	P38398-1.2	E1682P	Neutral	1.093
BRCA1	P38398-1.2	E1682Q	Neutral	1.221
BRCA1	P38398-1.2	E1682R	Neutral	1.136
BRCA1	P38398-1.2	E1682S	Neutral	1.136
BRCA1	P38398-1.2	E1682T	Neutral	1.093
BRCA1	P38398-1.2	E1682V	Neutral	1.051
BRCA1	P38398-1.2	E1682W	Neutral	1.008
BRCA1	P38398-1.2	E1682Y	Neutral	1.051
BRCA1	P38398-1.2	E1683A	Neutral	1.081
BRCA1	P38398-1.2	E1683C	Neutral	0.953
BRCA1	P38398-1.2	E1683D	Neutral	1.209
BRCA1	P38398-1.2	E1683F	Neutral	0.996
BRCA1	P38398-1.2	E1683G	Neutral	1.038
BRCA1	P38398-1.2	E1683H	Neutral	1.123
BRCA1	P38398-1.2	E1683I	Neutral	0.996
BRCA1	P38398-1.2	E1683K	Neutral	1.166
BRCA1	P38398-1.2	E1683L	Neutral	0.996
BRCA1	P38398-1.2	E1683M	Neutral	1.038
BRCA1	P38398-1.2	E1683N	Neutral	1.123
BRCA1	P38398-1.2	E1683P	Neutral	1.081
BRCA1	P38398-1.2	E1683Q	Neutral	1.209
BRCA1	P38398-1.2	E1683R	Neutral	1.123
BRCA1	P38398-1.2	E1683S	Neutral	1.123
BRCA1	P38398-1.2	E1683T	Neutral	1.081
BRCA1	P38398-1.2	E1683V	Neutral	1.038
BRCA1	P38398-1.2	E1683W	Neutral	0.996
BRCA1	P38398-1.2	E1683Y	Neutral	1.038
BRCA1	P38398-1.2	T1684A	Neutral	0.672
BRCA1	P38398-1.2	T1684C	Neutral	0.629
BRCA1	P38398-1.2	T1684D	Neutral	0.629
BRCA1	P38398-1.2	T1684E	Neutral	0.629
BRCA1	P38398-1.2	T1684F	Neutral	0.586
BRCA1	P38398-1.2	T1684G	Neutral	0.586
BRCA1	P38398-1.2	T1684H	Neutral	0.586
BRCA1	P38398-1.2	T1684I	Neutral	0.629
BRCA1	P38398-1.2	T1684K	Neutral	0.629
BRCA1	P38398-1.2	T1684L	Neutral	0.629
BRCA1	P38398-1.2	T1684M	Neutral	0.629
BRCA1	P38398-1.2	T1684N	Neutral	0.672
BRCA1	P38398-1.2	T1684P	Neutral	0.629
BRCA1	P38398-1.2	T1684Q	Neutral	0.629
BRCA1	P38398-1.2	T1684R	Neutral	0.629
BRCA1	P38398-1.2	T1684S	Neutral	0.714
BRCA1	P38398-1.2	T1684V	Neutral	0.672
BRCA1	P38398-1.2	T1684W	Neutral	0.586
BRCA1	P38398-1.2	T1684Y	Neutral	0.586
BRCA1	P38398-1.2	T1685A	Neutral	0.55
BRCA1	P38398-1.2	T1685C	Pathogenic	0.508
BRCA1	P38398-1.2	T1685D	Pathogenic	0.508
BRCA1	P38398-1.2	T1685E	Pathogenic	0.508
BRCA1	P38398-1.2	T1685F	Pathogenic	0.465
BRCA1	P38398-1.2	T1685G	Pathogenic	0.465
BRCA1	P38398-1.2	T1685H	Pathogenic	0.465
BRCA1	P38398-1.2	T1685I	Pathogenic	0.508
BRCA1	P38398-1.2	T1685K	Pathogenic	0.508
BRCA1	P38398-1.2	T1685L	Pathogenic	0.508
BRCA1	P38398-1.2	T1685M	Pathogenic	0.508
BRCA1	P38398-1.2	T1685N	Neutral	0.55
BRCA1	P38398-1.2	T1685P	Pathogenic	0.508
BRCA1	P38398-1.2	T1685Q	Pathogenic	0.508
BRCA1	P38398-1.2	T1685R	Pathogenic	0.508
BRCA1	P38398-1.2	T1685S	Neutral	0.593
BRCA1	P38398-1.2	T1685V	Neutral	0.55
BRCA1	P38398-1.2	T1685W	Pathogenic	0.465
BRCA1	P38398-1.2	T1685Y	Pathogenic	0.465
BRCA1	P38398-1.2	H1686A	Pathogenic	0.216
BRCA1	P38398-1.2	H1686C	Pathogenic	0.173
BRCA1	P38398-1.2	H1686D	Pathogenic	0.258
BRCA1	P38398-1.2	H1686E	Pathogenic	0.301
BRCA1	P38398-1.2	H1686F	Pathogenic	0.258
BRCA1	P38398-1.2	H1686G	Pathogenic	0.216
BRCA1	P38398-1.2	H1686I	Pathogenic	0.173
BRCA1	P38398-1.2	H1686K	Pathogenic	0.258
BRCA1	P38398-1.2	H1686L	Pathogenic	0.173
BRCA1	P38398-1.2	H1686M	Pathogenic	0.216
BRCA1	P38398-1.2	H1686N	Pathogenic	0.344
BRCA1	P38398-1.2	H1686P	Pathogenic	0.216
BRCA1	P38398-1.2	H1686Q	Pathogenic	0.301
BRCA1	P38398-1.2	H1686R	Pathogenic	0.301
BRCA1	P38398-1.2	H1686S	Pathogenic	0.258
BRCA1	P38398-1.2	H1686T	Pathogenic	0.216
BRCA1	P38398-1.2	H1686V	Pathogenic	0.173
BRCA1	P38398-1.2	H1686W	Pathogenic	0.216
BRCA1	P38398-1.2	H1686Y	Pathogenic	0.386
BRCA1	P38398-1.2	V1687A	Neutral	0.533
BRCA1	P38398-1.2	V1687C	Pathogenic	0.491
BRCA1	P38398-1.2	V1687D	Pathogenic	0.406
BRCA1	P38398-1.2	V1687E	Pathogenic	0.448
BRCA1	P38398-1.2	V1687F	Pathogenic	0.491
BRCA1	P38398-1.2	V1687G	Pathogenic	0.406
BRCA1	P38398-1.2	V1687H	Pathogenic	0.406
BRCA1	P38398-1.2	V1687I	Neutral	0.661
BRCA1	P38398-1.2	V1687K	Pathogenic	0.448
BRCA1	P38398-1.2	V1687L	Neutral	0.576
BRCA1	P38398-1.2	V1687M	Neutral	0.576
BRCA1	P38398-1.2	V1687N	Pathogenic	0.406
BRCA1	P38398-1.2	V1687P	Pathogenic	0.448
BRCA1	P38398-1.2	V1687Q	Pathogenic	0.448
BRCA1	P38398-1.2	V1687R	Pathogenic	0.406
BRCA1	P38398-1.2	V1687S	Pathogenic	0.448
BRCA1	P38398-1.2	V1687T	Neutral	0.533
BRCA1	P38398-1.2	V1687W	Pathogenic	0.406
BRCA1	P38398-1.2	V1687Y	Pathogenic	0.491
BRCA1	P38398-1.2	V1688A	Neutral	0.911
BRCA1	P38398-1.2	V1688C	Neutral	0.868
BRCA1	P38398-1.2	V1688D	Neutral	0.783
BRCA1	P38398-1.2	V1688E	Neutral	0.826
BRCA1	P38398-1.2	V1688F	Neutral	0.868
BRCA1	P38398-1.2	V1688G	Neutral	0.783
BRCA1	P38398-1.2	V1688H	Neutral	0.783
BRCA1	P38398-1.2	V1688I	Neutral	1.039
BRCA1	P38398-1.2	V1688K	Neutral	0.826
BRCA1	P38398-1.2	V1688L	Neutral	0.954
BRCA1	P38398-1.2	V1688M	Neutral	0.954
BRCA1	P38398-1.2	V1688N	Neutral	0.783
BRCA1	P38398-1.2	V1688P	Neutral	0.826
BRCA1	P38398-1.2	V1688Q	Neutral	0.826
BRCA1	P38398-1.2	V1688R	Neutral	0.783
BRCA1	P38398-1.2	V1688S	Neutral	0.826
BRCA1	P38398-1.2	V1688T	Neutral	0.911
BRCA1	P38398-1.2	V1688W	Neutral	0.783
BRCA1	P38398-1.2	V1688Y	Neutral	0.868
BRCA1	P38398-1.2	M1689A	Pathogenic	0.417
BRCA1	P38398-1.2	M1689C	Pathogenic	0.417
BRCA1	P38398-1.2	M1689D	Pathogenic	0.332
BRCA1	P38398-1.2	M1689E	Pathogenic	0.375
BRCA1	P38398-1.2	M1689F	Pathogenic	0.46
BRCA1	P38398-1.2	M1689G	Pathogenic	0.332
BRCA1	P38398-1.2	M1689H	Pathogenic	0.375
BRCA1	P38398-1.2	M1689I	Pathogenic	0.502
BRCA1	P38398-1.2	M1689K	Pathogenic	0.417
BRCA1	P38398-1.2	M1689L	Neutral	0.545
BRCA1	P38398-1.2	M1689N	Pathogenic	0.375
BRCA1	P38398-1.2	M1689P	Pathogenic	0.375
BRCA1	P38398-1.2	M1689Q	Pathogenic	0.46
BRCA1	P38398-1.2	M1689R	Pathogenic	0.417
BRCA1	P38398-1.2	M1689S	Pathogenic	0.417
BRCA1	P38398-1.2	M1689T	Pathogenic	0.417
BRCA1	P38398-1.2	M1689V	Pathogenic	0.502
BRCA1	P38398-1.2	M1689W	Pathogenic	0.417
BRCA1	P38398-1.2	M1689Y	Pathogenic	0.417
BRCA1	P38398-1.2	K1690A	Neutral	0.687
BRCA1	P38398-1.2	K1690C	Neutral	0.602
BRCA1	P38398-1.2	K1690D	Neutral	0.687
BRCA1	P38398-1.2	K1690E	Neutral	0.773
BRCA1	P38398-1.2	K1690F	Neutral	0.602
BRCA1	P38398-1.2	K1690G	Neutral	0.645
BRCA1	P38398-1.2	K1690H	Neutral	0.687
BRCA1	P38398-1.2	K1690I	Neutral	0.602
BRCA1	P38398-1.2	K1690L	Neutral	0.645
BRCA1	P38398-1.2	K1690M	Neutral	0.687
BRCA1	P38398-1.2	K1690N	Neutral	0.73
BRCA1	P38398-1.2	K1690P	Neutral	0.687
BRCA1	P38398-1.2	K1690Q	Neutral	0.773
BRCA1	P38398-1.2	K1690R	Neutral	0.815
BRCA1	P38398-1.2	K1690S	Neutral	0.73
BRCA1	P38398-1.2	K1690T	Neutral	0.687
BRCA1	P38398-1.2	K1690V	Neutral	0.645
BRCA1	P38398-1.2	K1690W	Neutral	0.602
BRCA1	P38398-1.2	K1690Y	Neutral	0.645
BRCA1	P38398-1.2	T1691A	Neutral	0.55
BRCA1	P38398-1.2	T1691C	Pathogenic	0.508
BRCA1	P38398-1.2	T1691D	Pathogenic	0.508
BRCA1	P38398-1.2	T1691E	Pathogenic	0.508
BRCA1	P38398-1.2	T1691F	Pathogenic	0.465
BRCA1	P38398-1.2	T1691G	Pathogenic	0.465
BRCA1	P38398-1.2	T1691H	Pathogenic	0.465
BRCA1	P38398-1.2	T1691I	Pathogenic	0.508
BRCA1	P38398-1.2	T1691K	Pathogenic	0.508
BRCA1	P38398-1.2	T1691L	Pathogenic	0.508
BRCA1	P38398-1.2	T1691M	Pathogenic	0.508
BRCA1	P38398-1.2	T1691N	Neutral	0.55
BRCA1	P38398-1.2	T1691P	Pathogenic	0.508
BRCA1	P38398-1.2	T1691Q	Pathogenic	0.508
BRCA1	P38398-1.2	T1691R	Pathogenic	0.508
BRCA1	P38398-1.2	T1691S	Neutral	0.593
BRCA1	P38398-1.2	T1691V	Neutral	0.55
BRCA1	P38398-1.2	T1691W	Pathogenic	0.465
BRCA1	P38398-1.2	T1691Y	Pathogenic	0.465
BRCA1	P38398-1.2	D1692A	Pathogenic	0.428
BRCA1	P38398-1.2	D1692C	Pathogenic	0.385
BRCA1	P38398-1.2	D1692E	Neutral	0.598
BRCA1	P38398-1.2	D1692F	Pathogenic	0.385
BRCA1	P38398-1.2	D1692G	Pathogenic	0.47
BRCA1	P38398-1.2	D1692H	Pathogenic	0.47
BRCA1	P38398-1.2	D1692I	Pathogenic	0.385
BRCA1	P38398-1.2	D1692K	Pathogenic	0.47
BRCA1	P38398-1.2	D1692L	Pathogenic	0.342
BRCA1	P38398-1.2	D1692M	Pathogenic	0.385
BRCA1	P38398-1.2	D1692N	Neutral	0.555
BRCA1	P38398-1.2	D1692P	Pathogenic	0.47
BRCA1	P38398-1.2	D1692Q	Pathogenic	0.513
BRCA1	P38398-1.2	D1692R	Pathogenic	0.428
BRCA1	P38398-1.2	D1692S	Pathogenic	0.513
BRCA1	P38398-1.2	D1692T	Pathogenic	0.47
BRCA1	P38398-1.2	D1692V	Pathogenic	0.385
BRCA1	P38398-1.2	D1692W	Pathogenic	0.342
BRCA1	P38398-1.2	D1692Y	Pathogenic	0.385
BRCA1	P38398-1.2	A1693C	Neutral	0.922
BRCA1	P38398-1.2	A1693D	Neutral	0.837
BRCA1	P38398-1.2	A1693E	Neutral	0.879
BRCA1	P38398-1.2	A1693F	Neutral	0.837
BRCA1	P38398-1.2	A1693G	Neutral	0.922
BRCA1	P38398-1.2	A1693H	Neutral	0.837
BRCA1	P38398-1.2	A1693I	Neutral	0.879
BRCA1	P38398-1.2	A1693K	Neutral	0.879
BRCA1	P38398-1.2	A1693L	Neutral	0.879
BRCA1	P38398-1.2	A1693M	Neutral	0.879
BRCA1	P38398-1.2	A1693N	Neutral	0.837
BRCA1	P38398-1.2	A1693P	Neutral	0.879
BRCA1	P38398-1.2	A1693Q	Neutral	0.879
BRCA1	P38398-1.2	A1693R	Neutral	0.879
BRCA1	P38398-1.2	A1693S	Neutral	0.964
BRCA1	P38398-1.2	A1693T	Neutral	0.922
BRCA1	P38398-1.2	A1693V	Neutral	0.922
BRCA1	P38398-1.2	A1693W	Neutral	0.794
BRCA1	P38398-1.2	A1693Y	Neutral	0.837
BRCA1	P38398-1.2	E1694A	Neutral	0.932
BRCA1	P38398-1.2	E1694C	Neutral	0.805
BRCA1	P38398-1.2	E1694D	Neutral	1.06
BRCA1	P38398-1.2	E1694F	Neutral	0.847
BRCA1	P38398-1.2	E1694G	Neutral	0.89
BRCA1	P38398-1.2	E1694H	Neutral	0.975
BRCA1	P38398-1.2	E1694I	Neutral	0.847
BRCA1	P38398-1.2	E1694K	Neutral	1.017
BRCA1	P38398-1.2	E1694L	Neutral	0.847
BRCA1	P38398-1.2	E1694M	Neutral	0.89
BRCA1	P38398-1.2	E1694N	Neutral	0.975
BRCA1	P38398-1.2	E1694P	Neutral	0.932
BRCA1	P38398-1.2	E1694Q	Neutral	1.06
BRCA1	P38398-1.2	E1694R	Neutral	0.975
BRCA1	P38398-1.2	E1694S	Neutral	0.975
BRCA1	P38398-1.2	E1694T	Neutral	0.932
BRCA1	P38398-1.2	E1694V	Neutral	0.89
BRCA1	P38398-1.2	E1694W	Neutral	0.847
BRCA1	P38398-1.2	E1694Y	Neutral	0.89
BRCA1	P38398-1.2	F1695A	Pathogenic	0.516
BRCA1	P38398-1.2	F1695C	Pathogenic	0.516
BRCA1	P38398-1.2	F1695D	Pathogenic	0.473
BRCA1	P38398-1.2	F1695E	Pathogenic	0.473
BRCA1	P38398-1.2	F1695G	Pathogenic	0.473
BRCA1	P38398-1.2	F1695H	Neutral	0.558
BRCA1	P38398-1.2	F1695I	Neutral	0.601
BRCA1	P38398-1.2	F1695K	Pathogenic	0.473
BRCA1	P38398-1.2	F1695L	Neutral	0.601
BRCA1	P38398-1.2	F1695M	Neutral	0.601
BRCA1	P38398-1.2	F1695N	Pathogenic	0.473
BRCA1	P38398-1.2	F1695P	Pathogenic	0.431
BRCA1	P38398-1.2	F1695Q	Pathogenic	0.473
BRCA1	P38398-1.2	F1695R	Pathogenic	0.473
BRCA1	P38398-1.2	F1695S	Pathogenic	0.516
BRCA1	P38398-1.2	F1695T	Pathogenic	0.516
BRCA1	P38398-1.2	F1695V	Neutral	0.558
BRCA1	P38398-1.2	F1695W	Neutral	0.644
BRCA1	P38398-1.2	F1695Y	Neutral	0.729
BRCA1	P38398-1.2	V1696A	Neutral	0.533
BRCA1	P38398-1.2	V1696C	Pathogenic	0.491
BRCA1	P38398-1.2	V1696D	Pathogenic	0.406
BRCA1	P38398-1.2	V1696E	Pathogenic	0.448
BRCA1	P38398-1.2	V1696F	Pathogenic	0.491
BRCA1	P38398-1.2	V1696G	Pathogenic	0.406
BRCA1	P38398-1.2	V1696H	Pathogenic	0.406
BRCA1	P38398-1.2	V1696I	Neutral	0.661
BRCA1	P38398-1.2	V1696K	Pathogenic	0.448
BRCA1	P38398-1.2	V1696L	Neutral	0.576
BRCA1	P38398-1.2	V1696M	Neutral	0.576
BRCA1	P38398-1.2	V1696N	Pathogenic	0.406
BRCA1	P38398-1.2	V1696P	Pathogenic	0.448
BRCA1	P38398-1.2	V1696Q	Pathogenic	0.448
BRCA1	P38398-1.2	V1696R	Pathogenic	0.406
BRCA1	P38398-1.2	V1696S	Pathogenic	0.448
BRCA1	P38398-1.2	V1696T	Neutral	0.533
BRCA1	P38398-1.2	V1696W	Pathogenic	0.406
BRCA1	P38398-1.2	V1696Y	Pathogenic	0.491
BRCA1	P38398-1.2	C1697A	Pathogenic	0.3
BRCA1	P38398-1.2	C1697D	Pathogenic	0.173
BRCA1	P38398-1.2	C1697E	Pathogenic	0.13
BRCA1	P38398-1.2	C1697F	Pathogenic	0.215
BRCA1	P38398-1.2	C1697G	Pathogenic	0.173
BRCA1	P38398-1.2	C1697H	Pathogenic	0.173
BRCA1	P38398-1.2	C1697I	Pathogenic	0.258
BRCA1	P38398-1.2	C1697K	Pathogenic	0.173
BRCA1	P38398-1.2	C1697L	Pathogenic	0.258
BRCA1	P38398-1.2	C1697M	Pathogenic	0.258
BRCA1	P38398-1.2	C1697N	Pathogenic	0.173
BRCA1	P38398-1.2	C1697P	Pathogenic	0.173
BRCA1	P38398-1.2	C1697Q	Pathogenic	0.173
BRCA1	P38398-1.2	C1697R	Pathogenic	0.173
BRCA1	P38398-1.2	C1697S	Pathogenic	0.258
BRCA1	P38398-1.2	C1697T	Pathogenic	0.258
BRCA1	P38398-1.2	C1697V	Pathogenic	0.258
BRCA1	P38398-1.2	C1697W	Pathogenic	0.215
BRCA1	P38398-1.2	C1697Y	Pathogenic	0.215
BRCA1	P38398-1.2	E1698A	Neutral	0.645
BRCA1	P38398-1.2	E1698C	Pathogenic	0.517
BRCA1	P38398-1.2	E1698D	Neutral	0.773
BRCA1	P38398-1.2	E1698F	Neutral	0.56
BRCA1	P38398-1.2	E1698G	Neutral	0.602
BRCA1	P38398-1.2	E1698H	Neutral	0.688
BRCA1	P38398-1.2	E1698I	Neutral	0.56
BRCA1	P38398-1.2	E1698K	Neutral	0.73
BRCA1	P38398-1.2	E1698L	Neutral	0.56
BRCA1	P38398-1.2	E1698M	Neutral	0.602
BRCA1	P38398-1.2	E1698N	Neutral	0.688
BRCA1	P38398-1.2	E1698P	Neutral	0.645
BRCA1	P38398-1.2	E1698Q	Neutral	0.773
BRCA1	P38398-1.2	E1698R	Neutral	0.688
BRCA1	P38398-1.2	E1698S	Neutral	0.688
BRCA1	P38398-1.2	E1698T	Neutral	0.645
BRCA1	P38398-1.2	E1698V	Neutral	0.602
BRCA1	P38398-1.2	E1698W	Neutral	0.56
BRCA1	P38398-1.2	E1698Y	Neutral	0.602
BRCA1	P38398-1.2	R1699A	Pathogenic	0.438
BRCA1	P38398-1.2	R1699C	Pathogenic	0.352
BRCA1	P38398-1.2	R1699D	Pathogenic	0.395
BRCA1	P38398-1.2	R1699E	Pathogenic	0.48
BRCA1	P38398-1.2	R1699F	Pathogenic	0.352
BRCA1	P38398-1.2	R1699G	Pathogenic	0.395
BRCA1	P38398-1.2	R1699H	Pathogenic	0.48
BRCA1	P38398-1.2	R1699I	Pathogenic	0.352
BRCA1	P38398-1.2	R1699K	Neutral	0.565
BRCA1	P38398-1.2	R1699L	Pathogenic	0.395
BRCA1	P38398-1.2	R1699M	Pathogenic	0.438
BRCA1	P38398-1.2	R1699N	Pathogenic	0.48
BRCA1	P38398-1.2	R1699P	Pathogenic	0.395
BRCA1	P38398-1.2	R1699Q	Pathogenic	0.523
BRCA1	P38398-1.2	R1699S	Pathogenic	0.438
BRCA1	P38398-1.2	R1699T	Pathogenic	0.438
BRCA1	P38398-1.2	R1699V	Pathogenic	0.352
BRCA1	P38398-1.2	R1699W	Pathogenic	0.352
BRCA1	P38398-1.2	R1699Y	Pathogenic	0.395
BRCA1	P38398-1.2	T1700A	Neutral	0.55
BRCA1	P38398-1.2	T1700C	Pathogenic	0.508
BRCA1	P38398-1.2	T1700D	Pathogenic	0.508
BRCA1	P38398-1.2	T1700E	Pathogenic	0.508
BRCA1	P38398-1.2	T1700F	Pathogenic	0.465
BRCA1	P38398-1.2	T1700G	Pathogenic	0.465
BRCA1	P38398-1.2	T1700H	Pathogenic	0.465
BRCA1	P38398-1.2	T1700I	Pathogenic	0.508
BRCA1	P38398-1.2	T1700K	Pathogenic	0.508
BRCA1	P38398-1.2	T1700L	Pathogenic	0.508
BRCA1	P38398-1.2	T1700M	Pathogenic	0.508
BRCA1	P38398-1.2	T1700N	Neutral	0.55
BRCA1	P38398-1.2	T1700P	Pathogenic	0.508
BRCA1	P38398-1.2	T1700Q	Pathogenic	0.508
BRCA1	P38398-1.2	T1700R	Pathogenic	0.508
BRCA1	P38398-1.2	T1700S	Neutral	0.593
BRCA1	P38398-1.2	T1700V	Neutral	0.55
BRCA1	P38398-1.2	T1700W	Pathogenic	0.465
BRCA1	P38398-1.2	T1700Y	Pathogenic	0.465
BRCA1	P38398-1.2	L1701A	Neutral	0.582
BRCA1	P38398-1.2	L1701C	Neutral	0.582
BRCA1	P38398-1.2	L1701D	Pathogenic	0.455
BRCA1	P38398-1.2	L1701E	Pathogenic	0.497
BRCA1	P38398-1.2	L1701F	Neutral	0.625
BRCA1	P38398-1.2	L1701G	Pathogenic	0.455
BRCA1	P38398-1.2	L1701H	Pathogenic	0.497
BRCA1	P38398-1.2	L1701I	Neutral	0.71
BRCA1	P38398-1.2	L1701K	Neutral	0.54
BRCA1	P38398-1.2	L1701M	Neutral	0.71
BRCA1	P38398-1.2	L1701N	Pathogenic	0.497
BRCA1	P38398-1.2	L1701P	Pathogenic	0.497
BRCA1	P38398-1.2	L1701Q	Neutral	0.54
BRCA1	P38398-1.2	L1701R	Neutral	0.54
BRCA1	P38398-1.2	L1701S	Neutral	0.54
BRCA1	P38398-1.2	L1701T	Neutral	0.582
BRCA1	P38398-1.2	L1701V	Neutral	0.668
BRCA1	P38398-1.2	L1701W	Neutral	0.54
BRCA1	P38398-1.2	L1701Y	Neutral	0.582
BRCA1	P38398-1.2	K1702A	Neutral	0.567
BRCA1	P38398-1.2	K1702C	Pathogenic	0.481
BRCA1	P38398-1.2	K1702D	Neutral	0.567
BRCA1	P38398-1.2	K1702E	Neutral	0.652
BRCA1	P38398-1.2	K1702F	Pathogenic	0.481
BRCA1	P38398-1.2	K1702G	Pathogenic	0.524
BRCA1	P38398-1.2	K1702H	Neutral	0.567
BRCA1	P38398-1.2	K1702I	Pathogenic	0.481
BRCA1	P38398-1.2	K1702L	Pathogenic	0.524
BRCA1	P38398-1.2	K1702M	Neutral	0.567
BRCA1	P38398-1.2	K1702N	Neutral	0.609
BRCA1	P38398-1.2	K1702P	Neutral	0.567
BRCA1	P38398-1.2	K1702Q	Neutral	0.652
BRCA1	P38398-1.2	K1702R	Neutral	0.694
BRCA1	P38398-1.2	K1702S	Neutral	0.609
BRCA1	P38398-1.2	K1702T	Neutral	0.567
BRCA1	P38398-1.2	K1702V	Pathogenic	0.524
BRCA1	P38398-1.2	K1702W	Pathogenic	0.481
BRCA1	P38398-1.2	K1702Y	Pathogenic	0.524
BRCA1	P38398-1.2	Y1703A	Pathogenic	0.048
BRCA1	P38398-1.2	Y1703C	Pathogenic	0.048
BRCA1	P38398-1.2	Y1703D	Pathogenic	0.005
BRCA1	P38398-1.2	Y1703E	Pathogenic	0.048
BRCA1	P38398-1.2	Y1703F	Pathogenic	0.26
BRCA1	P38398-1.2	Y1703G	Pathogenic	0.005
BRCA1	P38398-1.2	Y1703H	Pathogenic	0.218
BRCA1	P38398-1.2	Y1703I	Pathogenic	0.09
BRCA1	P38398-1.2	Y1703K	Pathogenic	0.048
BRCA1	P38398-1.2	Y1703L	Pathogenic	0.09
BRCA1	P38398-1.2	Y1703M	Pathogenic	0.09
BRCA1	P38398-1.2	Y1703N	Pathogenic	0.048
BRCA1	P38398-1.2	Y1703P	Pathogenic	0.005
BRCA1	P38398-1.2	Y1703Q	Pathogenic	0.09
BRCA1	P38398-1.2	Y1703R	Pathogenic	0.048
BRCA1	P38398-1.2	Y1703S	Pathogenic	0.048
BRCA1	P38398-1.2	Y1703T	Pathogenic	0.048
BRCA1	P38398-1.2	Y1703V	Pathogenic	0.09
BRCA1	P38398-1.2	Y1703W	Pathogenic	0.218
BRCA1	P38398-1.2	F1704A	Pathogenic	0.232
BRCA1	P38398-1.2	F1704C	Pathogenic	0.232
BRCA1	P38398-1.2	F1704D	Pathogenic	0.189
BRCA1	P38398-1.2	F1704E	Pathogenic	0.189
BRCA1	P38398-1.2	F1704G	Pathogenic	0.189
BRCA1	P38398-1.2	F1704H	Pathogenic	0.274
BRCA1	P38398-1.2	F1704I	Pathogenic	0.317
BRCA1	P38398-1.2	F1704K	Pathogenic	0.189
BRCA1	P38398-1.2	F1704L	Pathogenic	0.317
BRCA1	P38398-1.2	F1704M	Pathogenic	0.317
BRCA1	P38398-1.2	F1704N	Pathogenic	0.189
BRCA1	P38398-1.2	F1704P	Pathogenic	0.146
BRCA1	P38398-1.2	F1704Q	Pathogenic	0.189
BRCA1	P38398-1.2	F1704R	Pathogenic	0.189
BRCA1	P38398-1.2	F1704S	Pathogenic	0.232
BRCA1	P38398-1.2	F1704T	Pathogenic	0.232
BRCA1	P38398-1.2	F1704V	Pathogenic	0.274
BRCA1	P38398-1.2	F1704W	Pathogenic	0.359
BRCA1	P38398-1.2	F1704Y	Pathogenic	0.444
BRCA1	P38398-1.2	L1705A	Neutral	0.804
BRCA1	P38398-1.2	L1705C	Neutral	0.804
BRCA1	P38398-1.2	L1705D	Neutral	0.676
BRCA1	P38398-1.2	L1705E	Neutral	0.719
BRCA1	P38398-1.2	L1705F	Neutral	0.847
BRCA1	P38398-1.2	L1705G	Neutral	0.676
BRCA1	P38398-1.2	L1705H	Neutral	0.719
BRCA1	P38398-1.2	L1705I	Neutral	0.932
BRCA1	P38398-1.2	L1705K	Neutral	0.762
BRCA1	P38398-1.2	L1705M	Neutral	0.932
BRCA1	P38398-1.2	L1705N	Neutral	0.719
BRCA1	P38398-1.2	L1705P	Neutral	0.719
BRCA1	P38398-1.2	L1705Q	Neutral	0.762
BRCA1	P38398-1.2	L1705R	Neutral	0.762
BRCA1	P38398-1.2	L1705S	Neutral	0.762
BRCA1	P38398-1.2	L1705T	Neutral	0.804
BRCA1	P38398-1.2	L1705V	Neutral	0.889
BRCA1	P38398-1.2	L1705W	Neutral	0.762
BRCA1	P38398-1.2	L1705Y	Neutral	0.804
BRCA1	P38398-1.2	G1706A	Pathogenic	0.497
BRCA1	P38398-1.2	G1706C	Pathogenic	0.369
BRCA1	P38398-1.2	G1706D	Pathogenic	0.455
BRCA1	P38398-1.2	G1706E	Pathogenic	0.412
BRCA1	P38398-1.2	G1706F	Pathogenic	0.369
BRCA1	P38398-1.2	G1706H	Pathogenic	0.412
BRCA1	P38398-1.2	G1706I	Pathogenic	0.327
BRCA1	P38398-1.2	G1706K	Pathogenic	0.412
BRCA1	P38398-1.2	G1706L	Pathogenic	0.327
BRCA1	P38398-1.2	G1706M	Pathogenic	0.369
BRCA1	P38398-1.2	G1706N	Pathogenic	0.497
BRCA1	P38398-1.2	G1706P	Pathogenic	0.412
BRCA1	P38398-1.2	G1706Q	Pathogenic	0.412
BRCA1	P38398-1.2	G1706R	Pathogenic	0.412
BRCA1	P38398-1.2	G1706S	Pathogenic	0.497
BRCA1	P38398-1.2	G1706T	Pathogenic	0.412
BRCA1	P38398-1.2	G1706V	Pathogenic	0.369
BRCA1	P38398-1.2	G1706W	Pathogenic	0.412
BRCA1	P38398-1.2	G1706Y	Pathogenic	0.369
BRCA1	P38398-1.2	I1707A	Pathogenic	0.393
BRCA1	P38398-1.2	I1707C	Pathogenic	0.393
BRCA1	P38398-1.2	I1707D	Pathogenic	0.308
BRCA1	P38398-1.2	I1707E	Pathogenic	0.308
BRCA1	P38398-1.2	I1707F	Pathogenic	0.436
BRCA1	P38398-1.2	I1707G	Pathogenic	0.265
BRCA1	P38398-1.2	I1707H	Pathogenic	0.308
BRCA1	P38398-1.2	I1707K	Pathogenic	0.308
BRCA1	P38398-1.2	I1707L	Pathogenic	0.521
BRCA1	P38398-1.2	I1707M	Pathogenic	0.478
BRCA1	P38398-1.2	I1707N	Pathogenic	0.308
BRCA1	P38398-1.2	I1707P	Pathogenic	0.308
BRCA1	P38398-1.2	I1707Q	Pathogenic	0.308
BRCA1	P38398-1.2	I1707R	Pathogenic	0.308
BRCA1	P38398-1.2	I1707S	Pathogenic	0.351
BRCA1	P38398-1.2	I1707T	Pathogenic	0.393
BRCA1	P38398-1.2	I1707V	Neutral	0.563
BRCA1	P38398-1.2	I1707W	Pathogenic	0.308
BRCA1	P38398-1.2	I1707Y	Pathogenic	0.393
BRCA1	P38398-1.2	A1708C	Pathogenic	0.502
BRCA1	P38398-1.2	A1708D	Pathogenic	0.417
BRCA1	P38398-1.2	A1708E	Pathogenic	0.46
BRCA1	P38398-1.2	A1708F	Pathogenic	0.417
BRCA1	P38398-1.2	A1708G	Pathogenic	0.502
BRCA1	P38398-1.2	A1708H	Pathogenic	0.417
BRCA1	P38398-1.2	A1708I	Pathogenic	0.46
BRCA1	P38398-1.2	A1708K	Pathogenic	0.46
BRCA1	P38398-1.2	A1708L	Pathogenic	0.46
BRCA1	P38398-1.2	A1708M	Pathogenic	0.46
BRCA1	P38398-1.2	A1708N	Pathogenic	0.417
BRCA1	P38398-1.2	A1708P	Pathogenic	0.46
BRCA1	P38398-1.2	A1708Q	Pathogenic	0.46
BRCA1	P38398-1.2	A1708R	Pathogenic	0.46
BRCA1	P38398-1.2	A1708S	Neutral	0.545
BRCA1	P38398-1.2	A1708T	Pathogenic	0.502
BRCA1	P38398-1.2	A1708V	Pathogenic	0.502
BRCA1	P38398-1.2	A1708W	Pathogenic	0.375
BRCA1	P38398-1.2	A1708Y	Pathogenic	0.417
BRCA1	P38398-1.2	G1709A	Neutral	0.777
BRCA1	P38398-1.2	G1709C	Neutral	0.65
BRCA1	P38398-1.2	G1709D	Neutral	0.735
BRCA1	P38398-1.2	G1709E	Neutral	0.692
BRCA1	P38398-1.2	G1709F	Neutral	0.65
BRCA1	P38398-1.2	G1709H	Neutral	0.692
BRCA1	P38398-1.2	G1709I	Neutral	0.607
BRCA1	P38398-1.2	G1709K	Neutral	0.692
BRCA1	P38398-1.2	G1709L	Neutral	0.607
BRCA1	P38398-1.2	G1709M	Neutral	0.65
BRCA1	P38398-1.2	G1709N	Neutral	0.777
BRCA1	P38398-1.2	G1709P	Neutral	0.692
BRCA1	P38398-1.2	G1709Q	Neutral	0.692
BRCA1	P38398-1.2	G1709R	Neutral	0.692
BRCA1	P38398-1.2	G1709S	Neutral	0.777
BRCA1	P38398-1.2	G1709T	Neutral	0.692
BRCA1	P38398-1.2	G1709V	Neutral	0.65
BRCA1	P38398-1.2	G1709W	Neutral	0.692
BRCA1	P38398-1.2	G1709Y	Neutral	0.65
BRCA1	P38398-1.2	G1710A	Neutral	0.782
BRCA1	P38398-1.2	G1710C	Neutral	0.654
BRCA1	P38398-1.2	G1710D	Neutral	0.739
BRCA1	P38398-1.2	G1710E	Neutral	0.697
BRCA1	P38398-1.2	G1710F	Neutral	0.654
BRCA1	P38398-1.2	G1710H	Neutral	0.697
BRCA1	P38398-1.2	G1710I	Neutral	0.611
BRCA1	P38398-1.2	G1710K	Neutral	0.697
BRCA1	P38398-1.2	G1710L	Neutral	0.611
BRCA1	P38398-1.2	G1710M	Neutral	0.654
BRCA1	P38398-1.2	G1710N	Neutral	0.782
BRCA1	P38398-1.2	G1710P	Neutral	0.697
BRCA1	P38398-1.2	G1710Q	Neutral	0.697
BRCA1	P38398-1.2	G1710R	Neutral	0.697
BRCA1	P38398-1.2	G1710S	Neutral	0.782
BRCA1	P38398-1.2	G1710T	Neutral	0.697
BRCA1	P38398-1.2	G1710V	Neutral	0.654
BRCA1	P38398-1.2	G1710W	Neutral	0.697
BRCA1	P38398-1.2	G1710Y	Neutral	0.654
BRCA1	P38398-1.2	K1711A	Neutral	0.741
BRCA1	P38398-1.2	K1711C	Neutral	0.656
BRCA1	P38398-1.2	K1711D	Neutral	0.741
BRCA1	P38398-1.2	K1711E	Neutral	0.826
BRCA1	P38398-1.2	K1711F	Neutral	0.656
BRCA1	P38398-1.2	K1711G	Neutral	0.698
BRCA1	P38398-1.2	K1711H	Neutral	0.741
BRCA1	P38398-1.2	K1711I	Neutral	0.656
BRCA1	P38398-1.2	K1711L	Neutral	0.698
BRCA1	P38398-1.2	K1711M	Neutral	0.741
BRCA1	P38398-1.2	K1711N	Neutral	0.784
BRCA1	P38398-1.2	K1711P	Neutral	0.741
BRCA1	P38398-1.2	K1711Q	Neutral	0.826
BRCA1	P38398-1.2	K1711R	Neutral	0.869
BRCA1	P38398-1.2	K1711S	Neutral	0.784
BRCA1	P38398-1.2	K1711T	Neutral	0.741
BRCA1	P38398-1.2	K1711V	Neutral	0.698
BRCA1	P38398-1.2	K1711W	Neutral	0.656
BRCA1	P38398-1.2	K1711Y	Neutral	0.698
BRCA1	P38398-1.2	W1712A	Pathogenic	0.0
BRCA1	P38398-1.2	W1712C	Pathogenic	0.0
BRCA1	P38398-1.2	W1712D	Pathogenic	0.0
BRCA1	P38398-1.2	W1712E	Pathogenic	0.0
BRCA1	P38398-1.2	W1712F	Pathogenic	0.0
BRCA1	P38398-1.2	W1712G	Pathogenic	0.0
BRCA1	P38398-1.2	W1712H	Pathogenic	0.0
BRCA1	P38398-1.2	W1712I	Pathogenic	0.0
BRCA1	P38398-1.2	W1712K	Pathogenic	0.0
BRCA1	P38398-1.2	W1712L	Pathogenic	0.0
BRCA1	P38398-1.2	W1712M	Pathogenic	0.0
BRCA1	P38398-1.2	W1712N	Pathogenic	0.0
BRCA1	P38398-1.2	W1712P	Pathogenic	0.0
BRCA1	P38398-1.2	W1712Q	Pathogenic	0.0
BRCA1	P38398-1.2	W1712R	Pathogenic	0.0
BRCA1	P38398-1.2	W1712S	Pathogenic	0.0
BRCA1	P38398-1.2	W1712T	Pathogenic	0.0
BRCA1	P38398-1.2	W1712V	Pathogenic	0.0
BRCA1	P38398-1.2	W1712Y	Pathogenic	0.0
BRCA1	P38398-1.2	V1713A	Neutral	0.748
BRCA1	P38398-1.2	V1713C	Neutral	0.706
BRCA1	P38398-1.2	V1713D	Neutral	0.621
BRCA1	P38398-1.2	V1713E	Neutral	0.663
BRCA1	P38398-1.2	V1713F	Neutral	0.706
BRCA1	P38398-1.2	V1713G	Neutral	0.621
BRCA1	P38398-1.2	V1713H	Neutral	0.621
BRCA1	P38398-1.2	V1713I	Neutral	0.876
BRCA1	P38398-1.2	V1713K	Neutral	0.663
BRCA1	P38398-1.2	V1713L	Neutral	0.791
BRCA1	P38398-1.2	V1713M	Neutral	0.791
BRCA1	P38398-1.2	V1713N	Neutral	0.621
BRCA1	P38398-1.2	V1713P	Neutral	0.663
BRCA1	P38398-1.2	V1713Q	Neutral	0.663
BRCA1	P38398-1.2	V1713R	Neutral	0.621
BRCA1	P38398-1.2	V1713S	Neutral	0.663
BRCA1	P38398-1.2	V1713T	Neutral	0.748
BRCA1	P38398-1.2	V1713W	Neutral	0.621
BRCA1	P38398-1.2	V1713Y	Neutral	0.706
BRCA1	P38398-1.2	V1714A	Neutral	0.533
BRCA1	P38398-1.2	V1714C	Pathogenic	0.491
BRCA1	P38398-1.2	V1714D	Pathogenic	0.406
BRCA1	P38398-1.2	V1714E	Pathogenic	0.448
BRCA1	P38398-1.2	V1714F	Pathogenic	0.491
BRCA1	P38398-1.2	V1714G	Pathogenic	0.406
BRCA1	P38398-1.2	V1714H	Pathogenic	0.406
BRCA1	P38398-1.2	V1714I	Neutral	0.661
BRCA1	P38398-1.2	V1714K	Pathogenic	0.448
BRCA1	P38398-1.2	V1714L	Neutral	0.576
BRCA1	P38398-1.2	V1714M	Neutral	0.576
BRCA1	P38398-1.2	V1714N	Pathogenic	0.406
BRCA1	P38398-1.2	V1714P	Pathogenic	0.448
BRCA1	P38398-1.2	V1714Q	Pathogenic	0.448
BRCA1	P38398-1.2	V1714R	Pathogenic	0.406
BRCA1	P38398-1.2	V1714S	Pathogenic	0.448
BRCA1	P38398-1.2	V1714T	Neutral	0.533
BRCA1	P38398-1.2	V1714W	Pathogenic	0.406
BRCA1	P38398-1.2	V1714Y	Pathogenic	0.491
BRCA1	P38398-1.2	S1715A	Neutral	0.786
BRCA1	P38398-1.2	S1715C	Neutral	0.701
BRCA1	P38398-1.2	S1715D	Neutral	0.743
BRCA1	P38398-1.2	S1715E	Neutral	0.743
BRCA1	P38398-1.2	S1715F	Neutral	0.658
BRCA1	P38398-1.2	S1715G	Neutral	0.743
BRCA1	P38398-1.2	S1715H	Neutral	0.701
BRCA1	P38398-1.2	S1715I	Neutral	0.658
BRCA1	P38398-1.2	S1715K	Neutral	0.743
BRCA1	P38398-1.2	S1715L	Neutral	0.658
BRCA1	P38398-1.2	S1715M	Neutral	0.701
BRCA1	P38398-1.2	S1715N	Neutral	0.786
BRCA1	P38398-1.2	S1715P	Neutral	0.701
BRCA1	P38398-1.2	S1715Q	Neutral	0.743
BRCA1	P38398-1.2	S1715R	Neutral	0.701
BRCA1	P38398-1.2	S1715T	Neutral	0.786
BRCA1	P38398-1.2	S1715V	Neutral	0.658
BRCA1	P38398-1.2	S1715W	Neutral	0.615
BRCA1	P38398-1.2	S1715Y	Neutral	0.658
BRCA1	P38398-1.2	Y1716A	Pathogenic	0.305
BRCA1	P38398-1.2	Y1716C	Pathogenic	0.305
BRCA1	P38398-1.2	Y1716D	Pathogenic	0.262
BRCA1	P38398-1.2	Y1716E	Pathogenic	0.305
BRCA1	P38398-1.2	Y1716F	Pathogenic	0.518
BRCA1	P38398-1.2	Y1716G	Pathogenic	0.262
BRCA1	P38398-1.2	Y1716H	Pathogenic	0.475
BRCA1	P38398-1.2	Y1716I	Pathogenic	0.347
BRCA1	P38398-1.2	Y1716K	Pathogenic	0.305
BRCA1	P38398-1.2	Y1716L	Pathogenic	0.347
BRCA1	P38398-1.2	Y1716M	Pathogenic	0.347
BRCA1	P38398-1.2	Y1716N	Pathogenic	0.305
BRCA1	P38398-1.2	Y1716P	Pathogenic	0.262
BRCA1	P38398-1.2	Y1716Q	Pathogenic	0.347
BRCA1	P38398-1.2	Y1716R	Pathogenic	0.305
BRCA1	P38398-1.2	Y1716S	Pathogenic	0.305
BRCA1	P38398-1.2	Y1716T	Pathogenic	0.305
BRCA1	P38398-1.2	Y1716V	Pathogenic	0.347
BRCA1	P38398-1.2	Y1716W	Pathogenic	0.475
BRCA1	P38398-1.2	F1717A	Neutral	0.759
BRCA1	P38398-1.2	F1717C	Neutral	0.759
BRCA1	P38398-1.2	F1717D	Neutral	0.716
BRCA1	P38398-1.2	F1717E	Neutral	0.716
BRCA1	P38398-1.2	F1717G	Neutral	0.716
BRCA1	P38398-1.2	F1717H	Neutral	0.801
BRCA1	P38398-1.2	F1717I	Neutral	0.844
BRCA1	P38398-1.2	F1717K	Neutral	0.716
BRCA1	P38398-1.2	F1717L	Neutral	0.844
BRCA1	P38398-1.2	F1717M	Neutral	0.844
BRCA1	P38398-1.2	F1717N	Neutral	0.716
BRCA1	P38398-1.2	F1717P	Neutral	0.673
BRCA1	P38398-1.2	F1717Q	Neutral	0.716
BRCA1	P38398-1.2	F1717R	Neutral	0.716
BRCA1	P38398-1.2	F1717S	Neutral	0.759
BRCA1	P38398-1.2	F1717T	Neutral	0.759
BRCA1	P38398-1.2	F1717V	Neutral	0.801
BRCA1	P38398-1.2	F1717W	Neutral	0.886
BRCA1	P38398-1.2	F1717Y	Neutral	0.971
BRCA1	P38398-1.2	W1718A	Pathogenic	0.0
BRCA1	P38398-1.2	W1718C	Pathogenic	0.0
BRCA1	P38398-1.2	W1718D	Pathogenic	0.0
BRCA1	P38398-1.2	W1718E	Pathogenic	0.0
BRCA1	P38398-1.2	W1718F	Pathogenic	0.0
BRCA1	P38398-1.2	W1718G	Pathogenic	0.0
BRCA1	P38398-1.2	W1718H	Pathogenic	0.0
BRCA1	P38398-1.2	W1718I	Pathogenic	0.0
BRCA1	P38398-1.2	W1718K	Pathogenic	0.0
BRCA1	P38398-1.2	W1718L	Pathogenic	0.0
BRCA1	P38398-1.2	W1718M	Pathogenic	0.0
BRCA1	P38398-1.2	W1718N	Pathogenic	0.0
BRCA1	P38398-1.2	W1718P	Pathogenic	0.0
BRCA1	P38398-1.2	W1718Q	Pathogenic	0.0
BRCA1	P38398-1.2	W1718R	Pathogenic	0.0
BRCA1	P38398-1.2	W1718S	Pathogenic	0.0
BRCA1	P38398-1.2	W1718T	Pathogenic	0.0
BRCA1	P38398-1.2	W1718V	Pathogenic	0.0
BRCA1	P38398-1.2	W1718Y	Pathogenic	0.0
BRCA1	P38398-1.2	V1719A	Neutral	0.72
BRCA1	P38398-1.2	V1719C	Neutral	0.678
BRCA1	P38398-1.2	V1719D	Neutral	0.593
BRCA1	P38398-1.2	V1719E	Neutral	0.635
BRCA1	P38398-1.2	V1719F	Neutral	0.678
BRCA1	P38398-1.2	V1719G	Neutral	0.593
BRCA1	P38398-1.2	V1719H	Neutral	0.593
BRCA1	P38398-1.2	V1719I	Neutral	0.848
BRCA1	P38398-1.2	V1719K	Neutral	0.635
BRCA1	P38398-1.2	V1719L	Neutral	0.763
BRCA1	P38398-1.2	V1719M	Neutral	0.763
BRCA1	P38398-1.2	V1719N	Neutral	0.593
BRCA1	P38398-1.2	V1719P	Neutral	0.635
BRCA1	P38398-1.2	V1719Q	Neutral	0.635
BRCA1	P38398-1.2	V1719R	Neutral	0.593
BRCA1	P38398-1.2	V1719S	Neutral	0.635
BRCA1	P38398-1.2	V1719T	Neutral	0.72
BRCA1	P38398-1.2	V1719W	Neutral	0.593
BRCA1	P38398-1.2	V1719Y	Neutral	0.678
BRCA1	P38398-1.2	T1720A	Neutral	1.133
BRCA1	P38398-1.2	T1720C	Neutral	1.09
BRCA1	P38398-1.2	T1720D	Neutral	1.09
BRCA1	P38398-1.2	T1720E	Neutral	1.09
BRCA1	P38398-1.2	T1720F	Neutral	1.048
BRCA1	P38398-1.2	T1720G	Neutral	1.048
BRCA1	P38398-1.2	T1720H	Neutral	1.048
BRCA1	P38398-1.2	T1720I	Neutral	1.09
BRCA1	P38398-1.2	T1720K	Neutral	1.09
BRCA1	P38398-1.2	T1720L	Neutral	1.09
BRCA1	P38398-1.2	T1720M	Neutral	1.09
BRCA1	P38398-1.2	T1720N	Neutral	1.133
BRCA1	P38398-1.2	T1720P	Neutral	1.09
BRCA1	P38398-1.2	T1720Q	Neutral	1.09
BRCA1	P38398-1.2	T1720R	Neutral	1.09
BRCA1	P38398-1.2	T1720S	Neutral	1.176
BRCA1	P38398-1.2	T1720V	Neutral	1.133
BRCA1	P38398-1.2	T1720W	Neutral	1.048
BRCA1	P38398-1.2	T1720Y	Neutral	1.048
BRCA1	P38398-1.2	Q1721A	Neutral	0.853
BRCA1	P38398-1.2	Q1721C	Neutral	0.767
BRCA1	P38398-1.2	Q1721D	Neutral	0.895
BRCA1	P38398-1.2	Q1721E	Neutral	0.98
BRCA1	P38398-1.2	Q1721F	Neutral	0.767
BRCA1	P38398-1.2	Q1721G	Neutral	0.81
BRCA1	P38398-1.2	Q1721H	Neutral	0.895
BRCA1	P38398-1.2	Q1721I	Neutral	0.767
BRCA1	P38398-1.2	Q1721K	Neutral	0.938
BRCA1	P38398-1.2	Q1721L	Neutral	0.81
BRCA1	P38398-1.2	Q1721M	Neutral	0.895
BRCA1	P38398-1.2	Q1721N	Neutral	0.895
BRCA1	P38398-1.2	Q1721P	Neutral	0.853
BRCA1	P38398-1.2	Q1721R	Neutral	0.938
BRCA1	P38398-1.2	Q1721S	Neutral	0.895
BRCA1	P38398-1.2	Q1721T	Neutral	0.853
BRCA1	P38398-1.2	Q1721V	Neutral	0.81
BRCA1	P38398-1.2	Q1721W	Neutral	0.81
BRCA1	P38398-1.2	Q1721Y	Neutral	0.853
BRCA1	P38398-1.2	S1722A	Neutral	0.907
BRCA1	P38398-1.2	S1722C	Neutral	0.822
BRCA1	P38398-1.2	S1722D	Neutral	0.864
BRCA1	P38398-1.2	S1722E	Neutral	0.864
BRCA1	P38398-1.2	S1722F	Neutral	0.779
BRCA1	P38398-1.2	S1722G	Neutral	0.864
BRCA1	P38398-1.2	S1722H	Neutral	0.822
BRCA1	P38398-1.2	S1722I	Neutral	0.779
BRCA1	P38398-1.2	S1722K	Neutral	0.864
BRCA1	P38398-1.2	S1722L	Neutral	0.779
BRCA1	P38398-1.2	S1722M	Neutral	0.822
BRCA1	P38398-1.2	S1722N	Neutral	0.907
BRCA1	P38398-1.2	S1722P	Neutral	0.822
BRCA1	P38398-1.2	S1722Q	Neutral	0.864
BRCA1	P38398-1.2	S1722R	Neutral	0.822
BRCA1	P38398-1.2	S1722T	Neutral	0.907
BRCA1	P38398-1.2	S1722V	Neutral	0.779
BRCA1	P38398-1.2	S1722W	Neutral	0.737
BRCA1	P38398-1.2	S1722Y	Neutral	0.779
BRCA1	P38398-1.2	I1723A	Neutral	0.779
BRCA1	P38398-1.2	I1723C	Neutral	0.779
BRCA1	P38398-1.2	I1723D	Neutral	0.694
BRCA1	P38398-1.2	I1723E	Neutral	0.694
BRCA1	P38398-1.2	I1723F	Neutral	0.822
BRCA1	P38398-1.2	I1723G	Neutral	0.652
BRCA1	P38398-1.2	I1723H	Neutral	0.694
BRCA1	P38398-1.2	I1723K	Neutral	0.694
BRCA1	P38398-1.2	I1723L	Neutral	0.907
BRCA1	P38398-1.2	I1723M	Neutral	0.864
BRCA1	P38398-1.2	I1723N	Neutral	0.694
BRCA1	P38398-1.2	I1723P	Neutral	0.694
BRCA1	P38398-1.2	I1723Q	Neutral	0.694
BRCA1	P38398-1.2	I1723R	Neutral	0.694
BRCA1	P38398-1.2	I1723S	Neutral	0.737
BRCA1	P38398-1.2	I1723T	Neutral	0.779
BRCA1	P38398-1.2	I1723V	Neutral	0.95
BRCA1	P38398-1.2	I1723W	Neutral	0.694
BRCA1	P38398-1.2	I1723Y	Neutral	0.779
BRCA1	P38398-1.2	K1724A	Neutral	0.768
BRCA1	P38398-1.2	K1724C	Neutral	0.683
BRCA1	P38398-1.2	K1724D	Neutral	0.768
BRCA1	P38398-1.2	K1724E	Neutral	0.853
BRCA1	P38398-1.2	K1724F	Neutral	0.683
BRCA1	P38398-1.2	K1724G	Neutral	0.725
BRCA1	P38398-1.2	K1724H	Neutral	0.768
BRCA1	P38398-1.2	K1724I	Neutral	0.683
BRCA1	P38398-1.2	K1724L	Neutral	0.725
BRCA1	P38398-1.2	K1724M	Neutral	0.768
BRCA1	P38398-1.2	K1724N	Neutral	0.81
BRCA1	P38398-1.2	K1724P	Neutral	0.768
BRCA1	P38398-1.2	K1724Q	Neutral	0.853
BRCA1	P38398-1.2	K1724R	Neutral	0.896
BRCA1	P38398-1.2	K1724S	Neutral	0.81
BRCA1	P38398-1.2	K1724T	Neutral	0.768
BRCA1	P38398-1.2	K1724V	Neutral	0.725
BRCA1	P38398-1.2	K1724W	Neutral	0.683
BRCA1	P38398-1.2	K1724Y	Neutral	0.725
BRCA1	P38398-1.2	E1725A	Neutral	0.932
BRCA1	P38398-1.2	E1725C	Neutral	0.805
BRCA1	P38398-1.2	E1725D	Neutral	1.06
BRCA1	P38398-1.2	E1725F	Neutral	0.847
BRCA1	P38398-1.2	E1725G	Neutral	0.89
BRCA1	P38398-1.2	E1725H	Neutral	0.975
BRCA1	P38398-1.2	E1725I	Neutral	0.847
BRCA1	P38398-1.2	E1725K	Neutral	1.017
BRCA1	P38398-1.2	E1725L	Neutral	0.847
BRCA1	P38398-1.2	E1725M	Neutral	0.89
BRCA1	P38398-1.2	E1725N	Neutral	0.975
BRCA1	P38398-1.2	E1725P	Neutral	0.932
BRCA1	P38398-1.2	E1725Q	Neutral	1.06
BRCA1	P38398-1.2	E1725R	Neutral	0.975
BRCA1	P38398-1.2	E1725S	Neutral	0.975
BRCA1	P38398-1.2	E1725T	Neutral	0.932
BRCA1	P38398-1.2	E1725V	Neutral	0.89
BRCA1	P38398-1.2	E1725W	Neutral	0.847
BRCA1	P38398-1.2	E1725Y	Neutral	0.89
BRCA1	P38398-1.2	R1726A	Neutral	0.868
BRCA1	P38398-1.2	R1726C	Neutral	0.783
BRCA1	P38398-1.2	R1726D	Neutral	0.825
BRCA1	P38398-1.2	R1726E	Neutral	0.91
BRCA1	P38398-1.2	R1726F	Neutral	0.783
BRCA1	P38398-1.2	R1726G	Neutral	0.825
BRCA1	P38398-1.2	R1726H	Neutral	0.91
BRCA1	P38398-1.2	R1726I	Neutral	0.783
BRCA1	P38398-1.2	R1726K	Neutral	0.995
BRCA1	P38398-1.2	R1726L	Neutral	0.825
BRCA1	P38398-1.2	R1726M	Neutral	0.868
BRCA1	P38398-1.2	R1726N	Neutral	0.91
BRCA1	P38398-1.2	R1726P	Neutral	0.825
BRCA1	P38398-1.2	R1726Q	Neutral	0.953
BRCA1	P38398-1.2	R1726S	Neutral	0.868
BRCA1	P38398-1.2	R1726T	Neutral	0.868
BRCA1	P38398-1.2	R1726V	Neutral	0.783
BRCA1	P38398-1.2	R1726W	Neutral	0.783
BRCA1	P38398-1.2	R1726Y	Neutral	0.825
BRCA1	P38398-1.2	K1727A	Neutral	0.845
BRCA1	P38398-1.2	K1727C	Neutral	0.759
BRCA1	P38398-1.2	K1727D	Neutral	0.845
BRCA1	P38398-1.2	K1727E	Neutral	0.93
BRCA1	P38398-1.2	K1727F	Neutral	0.759
BRCA1	P38398-1.2	K1727G	Neutral	0.802
BRCA1	P38398-1.2	K1727H	Neutral	0.845
BRCA1	P38398-1.2	K1727I	Neutral	0.759
BRCA1	P38398-1.2	K1727L	Neutral	0.802
BRCA1	P38398-1.2	K1727M	Neutral	0.845
BRCA1	P38398-1.2	K1727N	Neutral	0.887
BRCA1	P38398-1.2	K1727P	Neutral	0.845
BRCA1	P38398-1.2	K1727Q	Neutral	0.93
BRCA1	P38398-1.2	K1727R	Neutral	0.972
BRCA1	P38398-1.2	K1727S	Neutral	0.887
BRCA1	P38398-1.2	K1727T	Neutral	0.845
BRCA1	P38398-1.2	K1727V	Neutral	0.802
BRCA1	P38398-1.2	K1727W	Neutral	0.759
BRCA1	P38398-1.2	K1727Y	Neutral	0.802
BRCA1	P38398-1.2	M1728A	Neutral	0.603
BRCA1	P38398-1.2	M1728C	Neutral	0.603
BRCA1	P38398-1.2	M1728D	Pathogenic	0.518
BRCA1	P38398-1.2	M1728E	Neutral	0.56
BRCA1	P38398-1.2	M1728F	Neutral	0.645
BRCA1	P38398-1.2	M1728G	Pathogenic	0.518
BRCA1	P38398-1.2	M1728H	Neutral	0.56
BRCA1	P38398-1.2	M1728I	Neutral	0.688
BRCA1	P38398-1.2	M1728K	Neutral	0.603
BRCA1	P38398-1.2	M1728L	Neutral	0.731
BRCA1	P38398-1.2	M1728N	Neutral	0.56
BRCA1	P38398-1.2	M1728P	Neutral	0.56
BRCA1	P38398-1.2	M1728Q	Neutral	0.645
BRCA1	P38398-1.2	M1728R	Neutral	0.603
BRCA1	P38398-1.2	M1728S	Neutral	0.603
BRCA1	P38398-1.2	M1728T	Neutral	0.603
BRCA1	P38398-1.2	M1728V	Neutral	0.688
BRCA1	P38398-1.2	M1728W	Neutral	0.603
BRCA1	P38398-1.2	M1728Y	Neutral	0.603
BRCA1	P38398-1.2	L1729A	Neutral	0.582
BRCA1	P38398-1.2	L1729C	Neutral	0.582
BRCA1	P38398-1.2	L1729D	Pathogenic	0.455
BRCA1	P38398-1.2	L1729E	Pathogenic	0.497
BRCA1	P38398-1.2	L1729F	Neutral	0.625
BRCA1	P38398-1.2	L1729G	Pathogenic	0.455
BRCA1	P38398-1.2	L1729H	Pathogenic	0.497
BRCA1	P38398-1.2	L1729I	Neutral	0.71
BRCA1	P38398-1.2	L1729K	Neutral	0.54
BRCA1	P38398-1.2	L1729M	Neutral	0.71
BRCA1	P38398-1.2	L1729N	Pathogenic	0.497
BRCA1	P38398-1.2	L1729P	Pathogenic	0.497
BRCA1	P38398-1.2	L1729Q	Neutral	0.54
BRCA1	P38398-1.2	L1729R	Neutral	0.54
BRCA1	P38398-1.2	L1729S	Neutral	0.54
BRCA1	P38398-1.2	L1729T	Neutral	0.582
BRCA1	P38398-1.2	L1729V	Neutral	0.668
BRCA1	P38398-1.2	L1729W	Neutral	0.54
BRCA1	P38398-1.2	L1729Y	Neutral	0.582
BRCA1	P38398-1.2	N1730A	Neutral	0.958
BRCA1	P38398-1.2	N1730C	Neutral	0.916
BRCA1	P38398-1.2	N1730D	Neutral	1.086
BRCA1	P38398-1.2	N1730E	Neutral	1.043
BRCA1	P38398-1.2	N1730F	Neutral	0.916
BRCA1	P38398-1.2	N1730G	Neutral	1.043
BRCA1	P38398-1.2	N1730H	Neutral	1.086
BRCA1	P38398-1.2	N1730I	Neutral	0.916
BRCA1	P38398-1.2	N1730K	Neutral	1.043
BRCA1	P38398-1.2	N1730L	Neutral	0.916
BRCA1	P38398-1.2	N1730M	Neutral	0.958
BRCA1	P38398-1.2	N1730P	Neutral	0.958
BRCA1	P38398-1.2	N1730Q	Neutral	1.043
BRCA1	P38398-1.2	N1730R	Neutral	1.043
BRCA1	P38398-1.2	N1730S	Neutral	1.086
BRCA1	P38398-1.2	N1730T	Neutral	1.043
BRCA1	P38398-1.2	N1730V	Neutral	0.916
BRCA1	P38398-1.2	N1730W	Neutral	0.873
BRCA1	P38398-1.2	N1730Y	Neutral	0.958
BRCA1	P38398-1.2	E1731A	Neutral	0.734
BRCA1	P38398-1.2	E1731C	Neutral	0.606
BRCA1	P38398-1.2	E1731D	Neutral	0.862
BRCA1	P38398-1.2	E1731F	Neutral	0.649
BRCA1	P38398-1.2	E1731G	Neutral	0.691
BRCA1	P38398-1.2	E1731H	Neutral	0.776
BRCA1	P38398-1.2	E1731I	Neutral	0.649
BRCA1	P38398-1.2	E1731K	Neutral	0.819
BRCA1	P38398-1.2	E1731L	Neutral	0.649
BRCA1	P38398-1.2	E1731M	Neutral	0.691
BRCA1	P38398-1.2	E1731N	Neutral	0.776
BRCA1	P38398-1.2	E1731P	Neutral	0.734
BRCA1	P38398-1.2	E1731Q	Neutral	0.862
BRCA1	P38398-1.2	E1731R	Neutral	0.776
BRCA1	P38398-1.2	E1731S	Neutral	0.776
BRCA1	P38398-1.2	E1731T	Neutral	0.734
BRCA1	P38398-1.2	E1731V	Neutral	0.691
BRCA1	P38398-1.2	E1731W	Neutral	0.649
BRCA1	P38398-1.2	E1731Y	Neutral	0.691
BRCA1	P38398-1.2	H1732A	Neutral	0.732
BRCA1	P38398-1.2	H1732C	Neutral	0.689
BRCA1	P38398-1.2	H1732D	Neutral	0.774
BRCA1	P38398-1.2	H1732E	Neutral	0.817
BRCA1	P38398-1.2	H1732F	Neutral	0.774
BRCA1	P38398-1.2	H1732G	Neutral	0.732
BRCA1	P38398-1.2	H1732I	Neutral	0.689
BRCA1	P38398-1.2	H1732K	Neutral	0.774
BRCA1	P38398-1.2	H1732L	Neutral	0.689
BRCA1	P38398-1.2	H1732M	Neutral	0.732
BRCA1	P38398-1.2	H1732N	Neutral	0.86
BRCA1	P38398-1.2	H1732P	Neutral	0.732
BRCA1	P38398-1.2	H1732Q	Neutral	0.817
BRCA1	P38398-1.2	H1732R	Neutral	0.817
BRCA1	P38398-1.2	H1732S	Neutral	0.774
BRCA1	P38398-1.2	H1732T	Neutral	0.732
BRCA1	P38398-1.2	H1732V	Neutral	0.689
BRCA1	P38398-1.2	H1732W	Neutral	0.732
BRCA1	P38398-1.2	H1732Y	Neutral	0.902
BRCA1	P38398-1.2	D1733A	Neutral	0.743
BRCA1	P38398-1.2	D1733C	Neutral	0.701
BRCA1	P38398-1.2	D1733E	Neutral	0.914
BRCA1	P38398-1.2	D1733F	Neutral	0.701
BRCA1	P38398-1.2	D1733G	Neutral	0.786
BRCA1	P38398-1.2	D1733H	Neutral	0.786
BRCA1	P38398-1.2	D1733I	Neutral	0.701
BRCA1	P38398-1.2	D1733K	Neutral	0.786
BRCA1	P38398-1.2	D1733L	Neutral	0.658
BRCA1	P38398-1.2	D1733M	Neutral	0.701
BRCA1	P38398-1.2	D1733N	Neutral	0.871
BRCA1	P38398-1.2	D1733P	Neutral	0.786
BRCA1	P38398-1.2	D1733Q	Neutral	0.828
BRCA1	P38398-1.2	D1733R	Neutral	0.743
BRCA1	P38398-1.2	D1733S	Neutral	0.828
BRCA1	P38398-1.2	D1733T	Neutral	0.786
BRCA1	P38398-1.2	D1733V	Neutral	0.701
BRCA1	P38398-1.2	D1733W	Neutral	0.658
BRCA1	P38398-1.2	D1733Y	Neutral	0.701
BRCA1	P38398-1.2	F1734A	Pathogenic	0.406
BRCA1	P38398-1.2	F1734C	Pathogenic	0.406
BRCA1	P38398-1.2	F1734D	Pathogenic	0.363
BRCA1	P38398-1.2	F1734E	Pathogenic	0.363
BRCA1	P38398-1.2	F1734G	Pathogenic	0.363
BRCA1	P38398-1.2	F1734H	Pathogenic	0.449
BRCA1	P38398-1.2	F1734I	Pathogenic	0.491
BRCA1	P38398-1.2	F1734K	Pathogenic	0.363
BRCA1	P38398-1.2	F1734L	Pathogenic	0.491
BRCA1	P38398-1.2	F1734M	Pathogenic	0.491
BRCA1	P38398-1.2	F1734N	Pathogenic	0.363
BRCA1	P38398-1.2	F1734P	Pathogenic	0.321
BRCA1	P38398-1.2	F1734Q	Pathogenic	0.363
BRCA1	P38398-1.2	F1734R	Pathogenic	0.363
BRCA1	P38398-1.2	F1734S	Pathogenic	0.406
BRCA1	P38398-1.2	F1734T	Pathogenic	0.406
BRCA1	P38398-1.2	F1734V	Pathogenic	0.449
BRCA1	P38398-1.2	F1734W	Neutral	0.534
BRCA1	P38398-1.2	F1734Y	Neutral	0.619
BRCA1	P38398-1.2	E1735A	Neutral	0.645
BRCA1	P38398-1.2	E1735C	Pathogenic	0.517
BRCA1	P38398-1.2	E1735D	Neutral	0.773
BRCA1	P38398-1.2	E1735F	Neutral	0.56
BRCA1	P38398-1.2	E1735G	Neutral	0.602
BRCA1	P38398-1.2	E1735H	Neutral	0.688
BRCA1	P38398-1.2	E1735I	Neutral	0.56
BRCA1	P38398-1.2	E1735K	Neutral	0.73
BRCA1	P38398-1.2	E1735L	Neutral	0.56
BRCA1	P38398-1.2	E1735M	Neutral	0.602
BRCA1	P38398-1.2	E1735N	Neutral	0.688
BRCA1	P38398-1.2	E1735P	Neutral	0.645
BRCA1	P38398-1.2	E1735Q	Neutral	0.773
BRCA1	P38398-1.2	E1735R	Neutral	0.688
BRCA1	P38398-1.2	E1735S	Neutral	0.688
BRCA1	P38398-1.2	E1735T	Neutral	0.645
BRCA1	P38398-1.2	E1735V	Neutral	0.602
BRCA1	P38398-1.2	E1735W	Neutral	0.56
BRCA1	P38398-1.2	E1735Y	Neutral	0.602
BRCA1	P38398-1.2	V1736A	Neutral	0.533
BRCA1	P38398-1.2	V1736C	Pathogenic	0.491
BRCA1	P38398-1.2	V1736D	Pathogenic	0.406
BRCA1	P38398-1.2	V1736E	Pathogenic	0.448
BRCA1	P38398-1.2	V1736F	Pathogenic	0.491
BRCA1	P38398-1.2	V1736G	Pathogenic	0.406
BRCA1	P38398-1.2	V1736H	Pathogenic	0.406
BRCA1	P38398-1.2	V1736I	Neutral	0.661
BRCA1	P38398-1.2	V1736K	Pathogenic	0.448
BRCA1	P38398-1.2	V1736L	Neutral	0.576
BRCA1	P38398-1.2	V1736M	Neutral	0.576
BRCA1	P38398-1.2	V1736N	Pathogenic	0.406
BRCA1	P38398-1.2	V1736P	Pathogenic	0.448
BRCA1	P38398-1.2	V1736Q	Pathogenic	0.448
BRCA1	P38398-1.2	V1736R	Pathogenic	0.406
BRCA1	P38398-1.2	V1736S	Pathogenic	0.448
BRCA1	P38398-1.2	V1736T	Neutral	0.533
BRCA1	P38398-1.2	V1736W	Pathogenic	0.406
BRCA1	P38398-1.2	V1736Y	Pathogenic	0.491
BRCA1	P38398-1.2	R1737A	Neutral	0.667
BRCA1	P38398-1.2	R1737C	Neutral	0.582
BRCA1	P38398-1.2	R1737D	Neutral	0.625
BRCA1	P38398-1.2	R1737E	Neutral	0.71
BRCA1	P38398-1.2	R1737F	Neutral	0.582
BRCA1	P38398-1.2	R1737G	Neutral	0.625
BRCA1	P38398-1.2	R1737H	Neutral	0.71
BRCA1	P38398-1.2	R1737I	Neutral	0.582
BRCA1	P38398-1.2	R1737K	Neutral	0.795
BRCA1	P38398-1.2	R1737L	Neutral	0.625
BRCA1	P38398-1.2	R1737M	Neutral	0.667
BRCA1	P38398-1.2	R1737N	Neutral	0.71
BRCA1	P38398-1.2	R1737P	Neutral	0.625
BRCA1	P38398-1.2	R1737Q	Neutral	0.752
BRCA1	P38398-1.2	R1737S	Neutral	0.667
BRCA1	P38398-1.2	R1737T	Neutral	0.667
BRCA1	P38398-1.2	R1737V	Neutral	0.582
BRCA1	P38398-1.2	R1737W	Neutral	0.582
BRCA1	P38398-1.2	R1737Y	Neutral	0.625
BRCA1	P38398-1.2	G1738A	Pathogenic	0.497
BRCA1	P38398-1.2	G1738C	Pathogenic	0.369
BRCA1	P38398-1.2	G1738D	Pathogenic	0.455
BRCA1	P38398-1.2	G1738E	Pathogenic	0.412
BRCA1	P38398-1.2	G1738F	Pathogenic	0.369
BRCA1	P38398-1.2	G1738H	Pathogenic	0.412
BRCA1	P38398-1.2	G1738I	Pathogenic	0.327
BRCA1	P38398-1.2	G1738K	Pathogenic	0.412
BRCA1	P38398-1.2	G1738L	Pathogenic	0.327
BRCA1	P38398-1.2	G1738M	Pathogenic	0.369
BRCA1	P38398-1.2	G1738N	Pathogenic	0.497
BRCA1	P38398-1.2	G1738P	Pathogenic	0.412
BRCA1	P38398-1.2	G1738Q	Pathogenic	0.412
BRCA1	P38398-1.2	G1738R	Pathogenic	0.412
BRCA1	P38398-1.2	G1738S	Pathogenic	0.497
BRCA1	P38398-1.2	G1738T	Pathogenic	0.412
BRCA1	P38398-1.2	G1738V	Pathogenic	0.369
BRCA1	P38398-1.2	G1738W	Pathogenic	0.412
BRCA1	P38398-1.2	G1738Y	Pathogenic	0.369
BRCA1	P38398-1.2	D1739A	Pathogenic	0.428
BRCA1	P38398-1.2	D1739C	Pathogenic	0.385
BRCA1	P38398-1.2	D1739E	Neutral	0.598
BRCA1	P38398-1.2	D1739F	Pathogenic	0.385
BRCA1	P38398-1.2	D1739G	Pathogenic	0.47
BRCA1	P38398-1.2	D1739H	Pathogenic	0.47
BRCA1	P38398-1.2	D1739I	Pathogenic	0.385
BRCA1	P38398-1.2	D1739K	Pathogenic	0.47
BRCA1	P38398-1.2	D1739L	Pathogenic	0.342
BRCA1	P38398-1.2	D1739M	Pathogenic	0.385
BRCA1	P38398-1.2	D1739N	Neutral	0.555
BRCA1	P38398-1.2	D1739P	Pathogenic	0.47
BRCA1	P38398-1.2	D1739Q	Pathogenic	0.513
BRCA1	P38398-1.2	D1739R	Pathogenic	0.428
BRCA1	P38398-1.2	D1739S	Pathogenic	0.513
BRCA1	P38398-1.2	D1739T	Pathogenic	0.47
BRCA1	P38398-1.2	D1739V	Pathogenic	0.385
BRCA1	P38398-1.2	D1739W	Pathogenic	0.342
BRCA1	P38398-1.2	D1739Y	Pathogenic	0.385
BRCA1	P38398-1.2	V1740A	Neutral	0.533
BRCA1	P38398-1.2	V1740C	Pathogenic	0.491
BRCA1	P38398-1.2	V1740D	Pathogenic	0.406
BRCA1	P38398-1.2	V1740E	Pathogenic	0.448
BRCA1	P38398-1.2	V1740F	Pathogenic	0.491
BRCA1	P38398-1.2	V1740G	Pathogenic	0.406
BRCA1	P38398-1.2	V1740H	Pathogenic	0.406
BRCA1	P38398-1.2	V1740I	Neutral	0.661
BRCA1	P38398-1.2	V1740K	Pathogenic	0.448
BRCA1	P38398-1.2	V1740L	Neutral	0.576
BRCA1	P38398-1.2	V1740M	Neutral	0.576
BRCA1	P38398-1.2	V1740N	Pathogenic	0.406
BRCA1	P38398-1.2	V1740P	Pathogenic	0.448
BRCA1	P38398-1.2	V1740Q	Pathogenic	0.448
BRCA1	P38398-1.2	V1740R	Pathogenic	0.406
BRCA1	P38398-1.2	V1740S	Pathogenic	0.448
BRCA1	P38398-1.2	V1740T	Neutral	0.533
BRCA1	P38398-1.2	V1740W	Pathogenic	0.406
BRCA1	P38398-1.2	V1740Y	Pathogenic	0.491
BRCA1	P38398-1.2	V1741A	Neutral	0.765
BRCA1	P38398-1.2	V1741C	Neutral	0.722
BRCA1	P38398-1.2	V1741D	Neutral	0.637
BRCA1	P38398-1.2	V1741E	Neutral	0.68
BRCA1	P38398-1.2	V1741F	Neutral	0.722
BRCA1	P38398-1.2	V1741G	Neutral	0.637
BRCA1	P38398-1.2	V1741H	Neutral	0.637
BRCA1	P38398-1.2	V1741I	Neutral	0.893
BRCA1	P38398-1.2	V1741K	Neutral	0.68
BRCA1	P38398-1.2	V1741L	Neutral	0.808
BRCA1	P38398-1.2	V1741M	Neutral	0.808
BRCA1	P38398-1.2	V1741N	Neutral	0.637
BRCA1	P38398-1.2	V1741P	Neutral	0.68
BRCA1	P38398-1.2	V1741Q	Neutral	0.68
BRCA1	P38398-1.2	V1741R	Neutral	0.637
BRCA1	P38398-1.2	V1741S	Neutral	0.68
BRCA1	P38398-1.2	V1741T	Neutral	0.765
BRCA1	P38398-1.2	V1741W	Neutral	0.637
BRCA1	P38398-1.2	V1741Y	Neutral	0.722
BRCA1	P38398-1.2	N1742A	Neutral	0.534
BRCA1	P38398-1.2	N1742C	Pathogenic	0.492
BRCA1	P38398-1.2	N1742D	Neutral	0.662
BRCA1	P38398-1.2	N1742E	Neutral	0.619
BRCA1	P38398-1.2	N1742F	Pathogenic	0.492
BRCA1	P38398-1.2	N1742G	Neutral	0.619
BRCA1	P38398-1.2	N1742H	Neutral	0.662
BRCA1	P38398-1.2	N1742I	Pathogenic	0.492
BRCA1	P38398-1.2	N1742K	Neutral	0.619
BRCA1	P38398-1.2	N1742L	Pathogenic	0.492
BRCA1	P38398-1.2	N1742M	Neutral	0.534
BRCA1	P38398-1.2	N1742P	Neutral	0.534
BRCA1	P38398-1.2	N1742Q	Neutral	0.619
BRCA1	P38398-1.2	N1742R	Neutral	0.619
BRCA1	P38398-1.2	N1742S	Neutral	0.662
BRCA1	P38398-1.2	N1742T	Neutral	0.619
BRCA1	P38398-1.2	N1742V	Pathogenic	0.492
BRCA1	P38398-1.2	N1742W	Pathogenic	0.449
BRCA1	P38398-1.2	N1742Y	Neutral	0.534
BRCA1	P38398-1.2	G1743A	Pathogenic	0.497
BRCA1	P38398-1.2	G1743C	Pathogenic	0.369
BRCA1	P38398-1.2	G1743D	Pathogenic	0.455
BRCA1	P38398-1.2	G1743E	Pathogenic	0.412
BRCA1	P38398-1.2	G1743F	Pathogenic	0.369
BRCA1	P38398-1.2	G1743H	Pathogenic	0.412
BRCA1	P38398-1.2	G1743I	Pathogenic	0.327
BRCA1	P38398-1.2	G1743K	Pathogenic	0.412
BRCA1	P38398-1.2	G1743L	Pathogenic	0.327
BRCA1	P38398-1.2	G1743M	Pathogenic	0.369
BRCA1	P38398-1.2	G1743N	Pathogenic	0.497
BRCA1	P38398-1.2	G1743P	Pathogenic	0.412
BRCA1	P38398-1.2	G1743Q	Pathogenic	0.412
BRCA1	P38398-1.2	G1743R	Pathogenic	0.412
BRCA1	P38398-1.2	G1743S	Pathogenic	0.497
BRCA1	P38398-1.2	G1743T	Pathogenic	0.412
BRCA1	P38398-1.2	G1743V	Pathogenic	0.369
BRCA1	P38398-1.2	G1743W	Pathogenic	0.412
BRCA1	P38398-1.2	G1743Y	Pathogenic	0.369
BRCA1	P38398-1.2	R1744A	Neutral	0.725
BRCA1	P38398-1.2	R1744C	Neutral	0.64
BRCA1	P38398-1.2	R1744D	Neutral	0.682
BRCA1	P38398-1.2	R1744E	Neutral	0.767
BRCA1	P38398-1.2	R1744F	Neutral	0.64
BRCA1	P38398-1.2	R1744G	Neutral	0.682
BRCA1	P38398-1.2	R1744H	Neutral	0.767
BRCA1	P38398-1.2	R1744I	Neutral	0.64
BRCA1	P38398-1.2	R1744K	Neutral	0.852
BRCA1	P38398-1.2	R1744L	Neutral	0.682
BRCA1	P38398-1.2	R1744M	Neutral	0.725
BRCA1	P38398-1.2	R1744N	Neutral	0.767
BRCA1	P38398-1.2	R1744P	Neutral	0.682
BRCA1	P38398-1.2	R1744Q	Neutral	0.81
BRCA1	P38398-1.2	R1744S	Neutral	0.725
BRCA1	P38398-1.2	R1744T	Neutral	0.725
BRCA1	P38398-1.2	R1744V	Neutral	0.64
BRCA1	P38398-1.2	R1744W	Neutral	0.64
BRCA1	P38398-1.2	R1744Y	Neutral	0.682
BRCA1	P38398-1.2	N1745A	Neutral	0.669
BRCA1	P38398-1.2	N1745C	Neutral	0.627
BRCA1	P38398-1.2	N1745D	Neutral	0.797
BRCA1	P38398-1.2	N1745E	Neutral	0.754
BRCA1	P38398-1.2	N1745F	Neutral	0.627
BRCA1	P38398-1.2	N1745G	Neutral	0.754
BRCA1	P38398-1.2	N1745H	Neutral	0.797
BRCA1	P38398-1.2	N1745I	Neutral	0.627
BRCA1	P38398-1.2	N1745K	Neutral	0.754
BRCA1	P38398-1.2	N1745L	Neutral	0.627
BRCA1	P38398-1.2	N1745M	Neutral	0.669
BRCA1	P38398-1.2	N1745P	Neutral	0.669
BRCA1	P38398-1.2	N1745Q	Neutral	0.754
BRCA1	P38398-1.2	N1745R	Neutral	0.754
BRCA1	P38398-1.2	N1745S	Neutral	0.797
BRCA1	P38398-1.2	N1745T	Neutral	0.754
BRCA1	P38398-1.2	N1745V	Neutral	0.627
BRCA1	P38398-1.2	N1745W	Neutral	0.584
BRCA1	P38398-1.2	N1745Y	Neutral	0.669
BRCA1	P38398-1.2	H1746A	Pathogenic	0.216
BRCA1	P38398-1.2	H1746C	Pathogenic	0.173
BRCA1	P38398-1.2	H1746D	Pathogenic	0.258
BRCA1	P38398-1.2	H1746E	Pathogenic	0.301
BRCA1	P38398-1.2	H1746F	Pathogenic	0.258
BRCA1	P38398-1.2	H1746G	Pathogenic	0.216
BRCA1	P38398-1.2	H1746I	Pathogenic	0.173
BRCA1	P38398-1.2	H1746K	Pathogenic	0.258
BRCA1	P38398-1.2	H1746L	Pathogenic	0.173
BRCA1	P38398-1.2	H1746M	Pathogenic	0.216
BRCA1	P38398-1.2	H1746N	Pathogenic	0.344
BRCA1	P38398-1.2	H1746P	Pathogenic	0.216
BRCA1	P38398-1.2	H1746Q	Pathogenic	0.301
BRCA1	P38398-1.2	H1746R	Pathogenic	0.301
BRCA1	P38398-1.2	H1746S	Pathogenic	0.258
BRCA1	P38398-1.2	H1746T	Pathogenic	0.216
BRCA1	P38398-1.2	H1746V	Pathogenic	0.173
BRCA1	P38398-1.2	H1746W	Pathogenic	0.216
BRCA1	P38398-1.2	H1746Y	Pathogenic	0.386
BRCA1	P38398-1.2	Q1747A	Neutral	0.817
BRCA1	P38398-1.2	Q1747C	Neutral	0.732
BRCA1	P38398-1.2	Q1747D	Neutral	0.86
BRCA1	P38398-1.2	Q1747E	Neutral	0.945
BRCA1	P38398-1.2	Q1747F	Neutral	0.732
BRCA1	P38398-1.2	Q1747G	Neutral	0.775
BRCA1	P38398-1.2	Q1747H	Neutral	0.86
BRCA1	P38398-1.2	Q1747I	Neutral	0.732
BRCA1	P38398-1.2	Q1747K	Neutral	0.902
BRCA1	P38398-1.2	Q1747L	Neutral	0.775
BRCA1	P38398-1.2	Q1747M	Neutral	0.86
BRCA1	P38398-1.2	Q1747N	Neutral	0.86
BRCA1	P38398-1.2	Q1747P	Neutral	0.817
BRCA1	P38398-1.2	Q1747R	Neutral	0.902
BRCA1	P38398-1.2	Q1747S	Neutral	0.86
BRCA1	P38398-1.2	Q1747T	Neutral	0.817
BRCA1	P38398-1.2	Q1747V	Neutral	0.775
BRCA1	P38398-1.2	Q1747W	Neutral	0.775
BRCA1	P38398-1.2	Q1747Y	Neutral	0.817
BRCA1	P38398-1.2	G1748A	Pathogenic	0.497
BRCA1	P38398-1.2	G1748C	Pathogenic	0.369
BRCA1	P38398-1.2	G1748D	Pathogenic	0.455
BRCA1	P38398-1.2	G1748E	Pathogenic	0.412
BRCA1	P38398-1.2	G1748F	Pathogenic	0.369
BRCA1	P38398-1.2	G1748H	Pathogenic	0.412
BRCA1	P38398-1.2	G1748I	Pathogenic	0.327
BRCA1	P38398-1.2	G1748K	Pathogenic	0.412
BRCA1	P38398-1.2	G1748L	Pathogenic	0.327
BRCA1	P38398-1.2	G1748M	Pathogenic	0.369
BRCA1	P38398-1.2	G1748N	Pathogenic	0.497
BRCA1	P38398-1.2	G1748P	Pathogenic	0.412
BRCA1	P38398-1.2	G1748Q	Pathogenic	0.412
BRCA1	P38398-1.2	G1748R	Pathogenic	0.412
BRCA1	P38398-1.2	G1748S	Pathogenic	0.497
BRCA1	P38398-1.2	G1748T	Pathogenic	0.412
BRCA1	P38398-1.2	G1748V	Pathogenic	0.369
BRCA1	P38398-1.2	G1748W	Pathogenic	0.412
BRCA1	P38398-1.2	G1748Y	Pathogenic	0.369
BRCA1	P38398-1.2	P1749A	Pathogenic	0.469
BRCA1	P38398-1.2	P1749C	Pathogenic	0.383
BRCA1	P38398-1.2	P1749D	Pathogenic	0.469
BRCA1	P38398-1.2	P1749E	Pathogenic	0.469
BRCA1	P38398-1.2	P1749F	Pathogenic	0.341
BRCA1	P38398-1.2	P1749G	Pathogenic	0.426
BRCA1	P38398-1.2	P1749H	Pathogenic	0.426
BRCA1	P38398-1.2	P1749I	Pathogenic	0.383
BRCA1	P38398-1.2	P1749K	Pathogenic	0.469
BRCA1	P38398-1.2	P1749L	Pathogenic	0.383
BRCA1	P38398-1.2	P1749M	Pathogenic	0.426
BRCA1	P38398-1.2	P1749N	Pathogenic	0.426
BRCA1	P38398-1.2	P1749Q	Pathogenic	0.469
BRCA1	P38398-1.2	P1749R	Pathogenic	0.426
BRCA1	P38398-1.2	P1749S	Pathogenic	0.469
BRCA1	P38398-1.2	P1749T	Pathogenic	0.469
BRCA1	P38398-1.2	P1749V	Pathogenic	0.426
BRCA1	P38398-1.2	P1749W	Pathogenic	0.341
BRCA1	P38398-1.2	P1749Y	Pathogenic	0.383
BRCA1	P38398-1.2	K1750A	Neutral	0.949
BRCA1	P38398-1.2	K1750C	Neutral	0.864
BRCA1	P38398-1.2	K1750D	Neutral	0.949
BRCA1	P38398-1.2	K1750E	Neutral	1.034
BRCA1	P38398-1.2	K1750F	Neutral	0.864
BRCA1	P38398-1.2	K1750G	Neutral	0.906
BRCA1	P38398-1.2	K1750H	Neutral	0.949
BRCA1	P38398-1.2	K1750I	Neutral	0.864
BRCA1	P38398-1.2	K1750L	Neutral	0.906
BRCA1	P38398-1.2	K1750M	Neutral	0.949
BRCA1	P38398-1.2	K1750N	Neutral	0.991
BRCA1	P38398-1.2	K1750P	Neutral	0.949
BRCA1	P38398-1.2	K1750Q	Neutral	1.034
BRCA1	P38398-1.2	K1750R	Neutral	1.076
BRCA1	P38398-1.2	K1750S	Neutral	0.991
BRCA1	P38398-1.2	K1750T	Neutral	0.949
BRCA1	P38398-1.2	K1750V	Neutral	0.906
BRCA1	P38398-1.2	K1750W	Neutral	0.864
BRCA1	P38398-1.2	K1750Y	Neutral	0.906
BRCA1	P38398-1.2	R1751A	Neutral	0.559
BRCA1	P38398-1.2	R1751C	Pathogenic	0.473
BRCA1	P38398-1.2	R1751D	Pathogenic	0.516
BRCA1	P38398-1.2	R1751E	Neutral	0.601
BRCA1	P38398-1.2	R1751F	Pathogenic	0.473
BRCA1	P38398-1.2	R1751G	Pathogenic	0.516
BRCA1	P38398-1.2	R1751H	Neutral	0.601
BRCA1	P38398-1.2	R1751I	Pathogenic	0.473
BRCA1	P38398-1.2	R1751K	Neutral	0.686
BRCA1	P38398-1.2	R1751L	Pathogenic	0.516
BRCA1	P38398-1.2	R1751M	Neutral	0.559
BRCA1	P38398-1.2	R1751N	Neutral	0.601
BRCA1	P38398-1.2	R1751P	Pathogenic	0.516
BRCA1	P38398-1.2	R1751Q	Neutral	0.644
BRCA1	P38398-1.2	R1751S	Neutral	0.559
BRCA1	P38398-1.2	R1751T	Neutral	0.559
BRCA1	P38398-1.2	R1751V	Pathogenic	0.473
BRCA1	P38398-1.2	R1751W	Pathogenic	0.473
BRCA1	P38398-1.2	R1751Y	Pathogenic	0.516
BRCA1	P38398-1.2	A1752C	Neutral	0.673
BRCA1	P38398-1.2	A1752D	Neutral	0.587
BRCA1	P38398-1.2	A1752E	Neutral	0.63
BRCA1	P38398-1.2	A1752F	Neutral	0.587
BRCA1	P38398-1.2	A1752G	Neutral	0.673
BRCA1	P38398-1.2	A1752H	Neutral	0.587
BRCA1	P38398-1.2	A1752I	Neutral	0.63
BRCA1	P38398-1.2	A1752K	Neutral	0.63
BRCA1	P38398-1.2	A1752L	Neutral	0.63
BRCA1	P38398-1.2	A1752M	Neutral	0.63
BRCA1	P38398-1.2	A1752N	Neutral	0.587
BRCA1	P38398-1.2	A1752P	Neutral	0.63
BRCA1	P38398-1.2	A1752Q	Neutral	0.63
BRCA1	P38398-1.2	A1752R	Neutral	0.63
BRCA1	P38398-1.2	A1752S	Neutral	0.715
BRCA1	P38398-1.2	A1752T	Neutral	0.673
BRCA1	P38398-1.2	A1752V	Neutral	0.673
BRCA1	P38398-1.2	A1752W	Neutral	0.545
BRCA1	P38398-1.2	A1752Y	Neutral	0.587
BRCA1	P38398-1.2	R1753A	Pathogenic	0.438
BRCA1	P38398-1.2	R1753C	Pathogenic	0.352
BRCA1	P38398-1.2	R1753D	Pathogenic	0.395
BRCA1	P38398-1.2	R1753E	Pathogenic	0.48
BRCA1	P38398-1.2	R1753F	Pathogenic	0.352
BRCA1	P38398-1.2	R1753G	Pathogenic	0.395
BRCA1	P38398-1.2	R1753H	Pathogenic	0.48
BRCA1	P38398-1.2	R1753I	Pathogenic	0.352
BRCA1	P38398-1.2	R1753K	Neutral	0.565
BRCA1	P38398-1.2	R1753L	Pathogenic	0.395
BRCA1	P38398-1.2	R1753M	Pathogenic	0.438
BRCA1	P38398-1.2	R1753N	Pathogenic	0.48
BRCA1	P38398-1.2	R1753P	Pathogenic	0.395
BRCA1	P38398-1.2	R1753Q	Pathogenic	0.523
BRCA1	P38398-1.2	R1753S	Pathogenic	0.438
BRCA1	P38398-1.2	R1753T	Pathogenic	0.438
BRCA1	P38398-1.2	R1753V	Pathogenic	0.352
BRCA1	P38398-1.2	R1753W	Pathogenic	0.352
BRCA1	P38398-1.2	R1753Y	Pathogenic	0.395
BRCA1	P38398-1.2	E1754A	Neutral	1.131
BRCA1	P38398-1.2	E1754C	Neutral	1.003
BRCA1	P38398-1.2	E1754D	Neutral	1.259
BRCA1	P38398-1.2	E1754F	Neutral	1.046
BRCA1	P38398-1.2	E1754G	Neutral	1.088
BRCA1	P38398-1.2	E1754H	Neutral	1.174
BRCA1	P38398-1.2	E1754I	Neutral	1.046
BRCA1	P38398-1.2	E1754K	Neutral	1.216
BRCA1	P38398-1.2	E1754L	Neutral	1.046
BRCA1	P38398-1.2	E1754M	Neutral	1.088
BRCA1	P38398-1.2	E1754N	Neutral	1.174
BRCA1	P38398-1.2	E1754P	Neutral	1.131
BRCA1	P38398-1.2	E1754Q	Neutral	1.259
BRCA1	P38398-1.2	E1754R	Neutral	1.174
BRCA1	P38398-1.2	E1754S	Neutral	1.174
BRCA1	P38398-1.2	E1754T	Neutral	1.131
BRCA1	P38398-1.2	E1754V	Neutral	1.088
BRCA1	P38398-1.2	E1754W	Neutral	1.046
BRCA1	P38398-1.2	E1754Y	Neutral	1.088
BRCA1	P38398-1.2	S1755A	Neutral	1.175
BRCA1	P38398-1.2	S1755C	Neutral	1.09
BRCA1	P38398-1.2	S1755D	Neutral	1.133
BRCA1	P38398-1.2	S1755E	Neutral	1.133
BRCA1	P38398-1.2	S1755F	Neutral	1.048
BRCA1	P38398-1.2	S1755G	Neutral	1.133
BRCA1	P38398-1.2	S1755H	Neutral	1.09
BRCA1	P38398-1.2	S1755I	Neutral	1.048
BRCA1	P38398-1.2	S1755K	Neutral	1.133
BRCA1	P38398-1.2	S1755L	Neutral	1.048
BRCA1	P38398-1.2	S1755M	Neutral	1.09
BRCA1	P38398-1.2	S1755N	Neutral	1.175
BRCA1	P38398-1.2	S1755P	Neutral	1.09
BRCA1	P38398-1.2	S1755Q	Neutral	1.133
BRCA1	P38398-1.2	S1755R	Neutral	1.09
BRCA1	P38398-1.2	S1755T	Neutral	1.175
BRCA1	P38398-1.2	S1755V	Neutral	1.048
BRCA1	P38398-1.2	S1755W	Neutral	1.005
BRCA1	P38398-1.2	S1755Y	Neutral	1.048
BRCA1	P38398-1.2	Q1756A	Neutral	1.156
BRCA1	P38398-1.2	Q1756C	Neutral	1.071
BRCA1	P38398-1.2	Q1756D	Neutral	1.198
BRCA1	P38398-1.2	Q1756E	Neutral	1.283
BRCA1	P38398-1.2	Q1756F	Neutral	1.071
BRCA1	P38398-1.2	Q1756G	Neutral	1.113
BRCA1	P38398-1.2	Q1756H	Neutral	1.198
BRCA1	P38398-1.2	Q1756I	Neutral	1.071
BRCA1	P38398-1.2	Q1756K	Neutral	1.241
BRCA1	P38398-1.2	Q1756L	Neutral	1.113
BRCA1	P38398-1.2	Q1756M	Neutral	1.198
BRCA1	P38398-1.2	Q1756N	Neutral	1.198
BRCA1	P38398-1.2	Q1756P	Neutral	1.156
BRCA1	P38398-1.2	Q1756R	Neutral	1.241
BRCA1	P38398-1.2	Q1756S	Neutral	1.198
BRCA1	P38398-1.2	Q1756T	Neutral	1.156
BRCA1	P38398-1.2	Q1756V	Neutral	1.113
BRCA1	P38398-1.2	Q1756W	Neutral	1.113
BRCA1	P38398-1.2	Q1756Y	Neutral	1.156
BRCA1	P38398-1.2	D1757A	Neutral	0.83
BRCA1	P38398-1.2	D1757C	Neutral	0.787
BRCA1	P38398-1.2	D1757E	Neutral	1.0
BRCA1	P38398-1.2	D1757F	Neutral	0.787
BRCA1	P38398-1.2	D1757G	Neutral	0.873
BRCA1	P38398-1.2	D1757H	Neutral	0.873
BRCA1	P38398-1.2	D1757I	Neutral	0.787
BRCA1	P38398-1.2	D1757K	Neutral	0.873
BRCA1	P38398-1.2	D1757L	Neutral	0.745
BRCA1	P38398-1.2	D1757M	Neutral	0.787
BRCA1	P38398-1.2	D1757N	Neutral	0.958
BRCA1	P38398-1.2	D1757P	Neutral	0.873
BRCA1	P38398-1.2	D1757Q	Neutral	0.915
BRCA1	P38398-1.2	D1757R	Neutral	0.83
BRCA1	P38398-1.2	D1757S	Neutral	0.915
BRCA1	P38398-1.2	D1757T	Neutral	0.873
BRCA1	P38398-1.2	D1757V	Neutral	0.787
BRCA1	P38398-1.2	D1757W	Neutral	0.745
BRCA1	P38398-1.2	D1757Y	Neutral	0.787
BRCA1	P38398-1.2	R1758A	Neutral	1.17
BRCA1	P38398-1.2	R1758C	Neutral	1.085
BRCA1	P38398-1.2	R1758D	Neutral	1.128
BRCA1	P38398-1.2	R1758E	Neutral	1.213
BRCA1	P38398-1.2	R1758F	Neutral	1.085
BRCA1	P38398-1.2	R1758G	Neutral	1.128
BRCA1	P38398-1.2	R1758H	Neutral	1.213
BRCA1	P38398-1.2	R1758I	Neutral	1.085
BRCA1	P38398-1.2	R1758K	Neutral	1.298
BRCA1	P38398-1.2	R1758L	Neutral	1.128
BRCA1	P38398-1.2	R1758M	Neutral	1.17
BRCA1	P38398-1.2	R1758N	Neutral	1.213
BRCA1	P38398-1.2	R1758P	Neutral	1.128
BRCA1	P38398-1.2	R1758Q	Neutral	1.256
BRCA1	P38398-1.2	R1758S	Neutral	1.17
BRCA1	P38398-1.2	R1758T	Neutral	1.17
BRCA1	P38398-1.2	R1758V	Neutral	1.085
BRCA1	P38398-1.2	R1758W	Neutral	1.085
BRCA1	P38398-1.2	R1758Y	Neutral	1.128
BRCA1	P38398-1.2	K1759A	Neutral	0.914
BRCA1	P38398-1.2	K1759C	Neutral	0.829
BRCA1	P38398-1.2	K1759D	Neutral	0.914
BRCA1	P38398-1.2	K1759E	Neutral	0.999
BRCA1	P38398-1.2	K1759F	Neutral	0.829
BRCA1	P38398-1.2	K1759G	Neutral	0.872
BRCA1	P38398-1.2	K1759H	Neutral	0.914
BRCA1	P38398-1.2	K1759I	Neutral	0.829
BRCA1	P38398-1.2	K1759L	Neutral	0.872
BRCA1	P38398-1.2	K1759M	Neutral	0.914
BRCA1	P38398-1.2	K1759N	Neutral	0.957
BRCA1	P38398-1.2	K1759P	Neutral	0.914
BRCA1	P38398-1.2	K1759Q	Neutral	0.999
BRCA1	P38398-1.2	K1759R	Neutral	1.042
BRCA1	P38398-1.2	K1759S	Neutral	0.957
BRCA1	P38398-1.2	K1759T	Neutral	0.914
BRCA1	P38398-1.2	K1759V	Neutral	0.872
BRCA1	P38398-1.2	K1759W	Neutral	0.829
BRCA1	P38398-1.2	K1759Y	Neutral	0.872
BRCA1	P38398-1.2	I1760A	Neutral	0.781
BRCA1	P38398-1.2	I1760C	Neutral	0.781
BRCA1	P38398-1.2	I1760D	Neutral	0.696
BRCA1	P38398-1.2	I1760E	Neutral	0.696
BRCA1	P38398-1.2	I1760F	Neutral	0.824
BRCA1	P38398-1.2	I1760G	Neutral	0.654
BRCA1	P38398-1.2	I1760H	Neutral	0.696
BRCA1	P38398-1.2	I1760K	Neutral	0.696
BRCA1	P38398-1.2	I1760L	Neutral	0.909
BRCA1	P38398-1.2	I1760M	Neutral	0.866
BRCA1	P38398-1.2	I1760N	Neutral	0.696
BRCA1	P38398-1.2	I1760P	Neutral	0.696
BRCA1	P38398-1.2	I1760Q	Neutral	0.696
BRCA1	P38398-1.2	I1760R	Neutral	0.696
BRCA1	P38398-1.2	I1760S	Neutral	0.739
BRCA1	P38398-1.2	I1760T	Neutral	0.781
BRCA1	P38398-1.2	I1760V	Neutral	0.952
BRCA1	P38398-1.2	I1760W	Neutral	0.696
BRCA1	P38398-1.2	I1760Y	Neutral	0.781
BRCA1	P38398-1.2	F1761A	Neutral	0.558
BRCA1	P38398-1.2	F1761C	Neutral	0.558
BRCA1	P38398-1.2	F1761D	Pathogenic	0.515
BRCA1	P38398-1.2	F1761E	Pathogenic	0.515
BRCA1	P38398-1.2	F1761G	Pathogenic	0.515
BRCA1	P38398-1.2	F1761H	Neutral	0.6
BRCA1	P38398-1.2	F1761I	Neutral	0.643
BRCA1	P38398-1.2	F1761K	Pathogenic	0.515
BRCA1	P38398-1.2	F1761L	Neutral	0.643
BRCA1	P38398-1.2	F1761M	Neutral	0.643
BRCA1	P38398-1.2	F1761N	Pathogenic	0.515
BRCA1	P38398-1.2	F1761P	Pathogenic	0.473
BRCA1	P38398-1.2	F1761Q	Pathogenic	0.515
BRCA1	P38398-1.2	F1761R	Pathogenic	0.515
BRCA1	P38398-1.2	F1761S	Neutral	0.558
BRCA1	P38398-1.2	F1761T	Neutral	0.558
BRCA1	P38398-1.2	F1761V	Neutral	0.6
BRCA1	P38398-1.2	F1761W	Neutral	0.686
BRCA1	P38398-1.2	F1761Y	Neutral	0.771
BRCA1	P38398-1.2	R1762A	Neutral	0.962
BRCA1	P38398-1.2	R1762C	Neutral	0.876
BRCA1	P38398-1.2	R1762D	Neutral	0.919
BRCA1	P38398-1.2	R1762E	Neutral	1.004
BRCA1	P38398-1.2	R1762F	Neutral	0.876
BRCA1	P38398-1.2	R1762G	Neutral	0.919
BRCA1	P38398-1.2	R1762H	Neutral	1.004
BRCA1	P38398-1.2	R1762I	Neutral	0.876
BRCA1	P38398-1.2	R1762K	Neutral	1.089
BRCA1	P38398-1.2	R1762L	Neutral	0.919
BRCA1	P38398-1.2	R1762M	Neutral	0.962
BRCA1	P38398-1.2	R1762N	Neutral	1.004
BRCA1	P38398-1.2	R1762P	Neutral	0.919
BRCA1	P38398-1.2	R1762Q	Neutral	1.047
BRCA1	P38398-1.2	R1762S	Neutral	0.962
BRCA1	P38398-1.2	R1762T	Neutral	0.962
BRCA1	P38398-1.2	R1762V	Neutral	0.876
BRCA1	P38398-1.2	R1762W	Neutral	0.876
BRCA1	P38398-1.2	R1762Y	Neutral	0.919
BRCA1	P38398-1.2	G1763A	Neutral	0.839
BRCA1	P38398-1.2	G1763C	Neutral	0.712
BRCA1	P38398-1.2	G1763D	Neutral	0.797
BRCA1	P38398-1.2	G1763E	Neutral	0.754
BRCA1	P38398-1.2	G1763F	Neutral	0.712
BRCA1	P38398-1.2	G1763H	Neutral	0.754
BRCA1	P38398-1.2	G1763I	Neutral	0.669
BRCA1	P38398-1.2	G1763K	Neutral	0.754
BRCA1	P38398-1.2	G1763L	Neutral	0.669
BRCA1	P38398-1.2	G1763M	Neutral	0.712
BRCA1	P38398-1.2	G1763N	Neutral	0.839
BRCA1	P38398-1.2	G1763P	Neutral	0.754
BRCA1	P38398-1.2	G1763Q	Neutral	0.754
BRCA1	P38398-1.2	G1763R	Neutral	0.754
BRCA1	P38398-1.2	G1763S	Neutral	0.839
BRCA1	P38398-1.2	G1763T	Neutral	0.754
BRCA1	P38398-1.2	G1763V	Neutral	0.712
BRCA1	P38398-1.2	G1763W	Neutral	0.754
BRCA1	P38398-1.2	G1763Y	Neutral	0.712
BRCA1	P38398-1.2	L1764A	Neutral	0.947
BRCA1	P38398-1.2	L1764C	Neutral	0.947
BRCA1	P38398-1.2	L1764D	Neutral	0.819
BRCA1	P38398-1.2	L1764E	Neutral	0.861
BRCA1	P38398-1.2	L1764F	Neutral	0.989
BRCA1	P38398-1.2	L1764G	Neutral	0.819
BRCA1	P38398-1.2	L1764H	Neutral	0.861
BRCA1	P38398-1.2	L1764I	Neutral	1.074
BRCA1	P38398-1.2	L1764K	Neutral	0.904
BRCA1	P38398-1.2	L1764M	Neutral	1.074
BRCA1	P38398-1.2	L1764N	Neutral	0.861
BRCA1	P38398-1.2	L1764P	Neutral	0.861
BRCA1	P38398-1.2	L1764Q	Neutral	0.904
BRCA1	P38398-1.2	L1764R	Neutral	0.904
BRCA1	P38398-1.2	L1764S	Neutral	0.904
BRCA1	P38398-1.2	L1764T	Neutral	0.947
BRCA1	P38398-1.2	L1764V	Neutral	1.032
BRCA1	P38398-1.2	L1764W	Neutral	0.904
BRCA1	P38398-1.2	L1764Y	Neutral	0.947
BRCA1	P38398-1.2	E1765A	Neutral	1.052
BRCA1	P38398-1.2	E1765C	Neutral	0.924
BRCA1	P38398-1.2	E1765D	Neutral	1.18
BRCA1	P38398-1.2	E1765F	Neutral	0.967
BRCA1	P38398-1.2	E1765G	Neutral	1.009
BRCA1	P38398-1.2	E1765H	Neutral	1.094
BRCA1	P38398-1.2	E1765I	Neutral	0.967
BRCA1	P38398-1.2	E1765K	Neutral	1.137
BRCA1	P38398-1.2	E1765L	Neutral	0.967
BRCA1	P38398-1.2	E1765M	Neutral	1.009
BRCA1	P38398-1.2	E1765N	Neutral	1.094
BRCA1	P38398-1.2	E1765P	Neutral	1.052
BRCA1	P38398-1.2	E1765Q	Neutral	1.18
BRCA1	P38398-1.2	E1765R	Neutral	1.094
BRCA1	P38398-1.2	E1765S	Neutral	1.094
BRCA1	P38398-1.2	E1765T	Neutral	1.052
BRCA1	P38398-1.2	E1765V	Neutral	1.009
BRCA1	P38398-1.2	E1765W	Neutral	0.967
BRCA1	P38398-1.2	E1765Y	Neutral	1.009
BRCA1	P38398-1.2	I1766A	Neutral	0.653
BRCA1	P38398-1.2	I1766C	Neutral	0.653
BRCA1	P38398-1.2	I1766D	Neutral	0.568
BRCA1	P38398-1.2	I1766E	Neutral	0.568
BRCA1	P38398-1.2	I1766F	Neutral	0.695
BRCA1	P38398-1.2	I1766G	Pathogenic	0.525
BRCA1	P38398-1.2	I1766H	Neutral	0.568
BRCA1	P38398-1.2	I1766K	Neutral	0.568
BRCA1	P38398-1.2	I1766L	Neutral	0.781
BRCA1	P38398-1.2	I1766M	Neutral	0.738
BRCA1	P38398-1.2	I1766N	Neutral	0.568
BRCA1	P38398-1.2	I1766P	Neutral	0.568
BRCA1	P38398-1.2	I1766Q	Neutral	0.568
BRCA1	P38398-1.2	I1766R	Neutral	0.568
BRCA1	P38398-1.2	I1766S	Neutral	0.61
BRCA1	P38398-1.2	I1766T	Neutral	0.653
BRCA1	P38398-1.2	I1766V	Neutral	0.823
BRCA1	P38398-1.2	I1766W	Neutral	0.568
BRCA1	P38398-1.2	I1766Y	Neutral	0.653
BRCA1	P38398-1.2	C1767A	Pathogenic	0.39
BRCA1	P38398-1.2	C1767D	Pathogenic	0.262
BRCA1	P38398-1.2	C1767E	Pathogenic	0.219
BRCA1	P38398-1.2	C1767F	Pathogenic	0.304
BRCA1	P38398-1.2	C1767G	Pathogenic	0.262
BRCA1	P38398-1.2	C1767H	Pathogenic	0.262
BRCA1	P38398-1.2	C1767I	Pathogenic	0.347
BRCA1	P38398-1.2	C1767K	Pathogenic	0.262
BRCA1	P38398-1.2	C1767L	Pathogenic	0.347
BRCA1	P38398-1.2	C1767M	Pathogenic	0.347
BRCA1	P38398-1.2	C1767N	Pathogenic	0.262
BRCA1	P38398-1.2	C1767P	Pathogenic	0.262
BRCA1	P38398-1.2	C1767Q	Pathogenic	0.262
BRCA1	P38398-1.2	C1767R	Pathogenic	0.262
BRCA1	P38398-1.2	C1767S	Pathogenic	0.347
BRCA1	P38398-1.2	C1767T	Pathogenic	0.347
BRCA1	P38398-1.2	C1767V	Pathogenic	0.347
BRCA1	P38398-1.2	C1767W	Pathogenic	0.304
BRCA1	P38398-1.2	C1767Y	Pathogenic	0.304
BRCA1	P38398-1.2	C1768A	Pathogenic	0.49
BRCA1	P38398-1.2	C1768D	Pathogenic	0.363
BRCA1	P38398-1.2	C1768E	Pathogenic	0.32
BRCA1	P38398-1.2	C1768F	Pathogenic	0.405
BRCA1	P38398-1.2	C1768G	Pathogenic	0.363
BRCA1	P38398-1.2	C1768H	Pathogenic	0.363
BRCA1	P38398-1.2	C1768I	Pathogenic	0.448
BRCA1	P38398-1.2	C1768K	Pathogenic	0.363
BRCA1	P38398-1.2	C1768L	Pathogenic	0.448
BRCA1	P38398-1.2	C1768M	Pathogenic	0.448
BRCA1	P38398-1.2	C1768N	Pathogenic	0.363
BRCA1	P38398-1.2	C1768P	Pathogenic	0.363
BRCA1	P38398-1.2	C1768Q	Pathogenic	0.363
BRCA1	P38398-1.2	C1768R	Pathogenic	0.363
BRCA1	P38398-1.2	C1768S	Pathogenic	0.448
BRCA1	P38398-1.2	C1768T	Pathogenic	0.448
BRCA1	P38398-1.2	C1768V	Pathogenic	0.448
BRCA1	P38398-1.2	C1768W	Pathogenic	0.405
BRCA1	P38398-1.2	C1768Y	Pathogenic	0.405
BRCA1	P38398-1.2	Y1769A	Neutral	0.586
BRCA1	P38398-1.2	Y1769C	Neutral	0.586
BRCA1	P38398-1.2	Y1769D	Neutral	0.543
BRCA1	P38398-1.2	Y1769E	Neutral	0.586
BRCA1	P38398-1.2	Y1769F	Neutral	0.799
BRCA1	P38398-1.2	Y1769G	Neutral	0.543
BRCA1	P38398-1.2	Y1769H	Neutral	0.756
BRCA1	P38398-1.2	Y1769I	Neutral	0.629
BRCA1	P38398-1.2	Y1769K	Neutral	0.586
BRCA1	P38398-1.2	Y1769L	Neutral	0.629
BRCA1	P38398-1.2	Y1769M	Neutral	0.629
BRCA1	P38398-1.2	Y1769N	Neutral	0.586
BRCA1	P38398-1.2	Y1769P	Neutral	0.543
BRCA1	P38398-1.2	Y1769Q	Neutral	0.629
BRCA1	P38398-1.2	Y1769R	Neutral	0.586
BRCA1	P38398-1.2	Y1769S	Neutral	0.586
BRCA1	P38398-1.2	Y1769T	Neutral	0.586
BRCA1	P38398-1.2	Y1769V	Neutral	0.629
BRCA1	P38398-1.2	Y1769W	Neutral	0.756
BRCA1	P38398-1.2	G1770A	Neutral	0.586
BRCA1	P38398-1.2	G1770C	Pathogenic	0.459
BRCA1	P38398-1.2	G1770D	Neutral	0.544
BRCA1	P38398-1.2	G1770E	Pathogenic	0.501
BRCA1	P38398-1.2	G1770F	Pathogenic	0.459
BRCA1	P38398-1.2	G1770H	Pathogenic	0.501
BRCA1	P38398-1.2	G1770I	Pathogenic	0.416
BRCA1	P38398-1.2	G1770K	Pathogenic	0.501
BRCA1	P38398-1.2	G1770L	Pathogenic	0.416
BRCA1	P38398-1.2	G1770M	Pathogenic	0.459
BRCA1	P38398-1.2	G1770N	Neutral	0.586
BRCA1	P38398-1.2	G1770P	Pathogenic	0.501
BRCA1	P38398-1.2	G1770Q	Pathogenic	0.501
BRCA1	P38398-1.2	G1770R	Pathogenic	0.501
BRCA1	P38398-1.2	G1770S	Neutral	0.586
BRCA1	P38398-1.2	G1770T	Pathogenic	0.501
BRCA1	P38398-1.2	G1770V	Pathogenic	0.459
BRCA1	P38398-1.2	G1770W	Pathogenic	0.501
BRCA1	P38398-1.2	G1770Y	Pathogenic	0.459
BRCA1	P38398-1.2	P1771A	Neutral	0.581
BRCA1	P38398-1.2	P1771C	Pathogenic	0.496
BRCA1	P38398-1.2	P1771D	Neutral	0.581
BRCA1	P38398-1.2	P1771E	Neutral	0.581
BRCA1	P38398-1.2	P1771F	Pathogenic	0.454
BRCA1	P38398-1.2	P1771G	Neutral	0.539
BRCA1	P38398-1.2	P1771H	Neutral	0.539
BRCA1	P38398-1.2	P1771I	Pathogenic	0.496
BRCA1	P38398-1.2	P1771K	Neutral	0.581
BRCA1	P38398-1.2	P1771L	Pathogenic	0.496
BRCA1	P38398-1.2	P1771M	Neutral	0.539
BRCA1	P38398-1.2	P1771N	Neutral	0.539
BRCA1	P38398-1.2	P1771Q	Neutral	0.581
BRCA1	P38398-1.2	P1771R	Neutral	0.539
BRCA1	P38398-1.2	P1771S	Neutral	0.581
BRCA1	P38398-1.2	P1771T	Neutral	0.581
BRCA1	P38398-1.2	P1771V	Neutral	0.539
BRCA1	P38398-1.2	P1771W	Pathogenic	0.454
BRCA1	P38398-1.2	P1771Y	Pathogenic	0.496
BRCA1	P38398-1.2	F1772A	Pathogenic	0.232
BRCA1	P38398-1.2	F1772C	Pathogenic	0.232
BRCA1	P38398-1.2	F1772D	Pathogenic	0.189
BRCA1	P38398-1.2	F1772E	Pathogenic	0.189
BRCA1	P38398-1.2	F1772G	Pathogenic	0.189
BRCA1	P38398-1.2	F1772H	Pathogenic	0.274
BRCA1	P38398-1.2	F1772I	Pathogenic	0.317
BRCA1	P38398-1.2	F1772K	Pathogenic	0.189
BRCA1	P38398-1.2	F1772L	Pathogenic	0.317
BRCA1	P38398-1.2	F1772M	Pathogenic	0.317
BRCA1	P38398-1.2	F1772N	Pathogenic	0.189
BRCA1	P38398-1.2	F1772P	Pathogenic	0.146
BRCA1	P38398-1.2	F1772Q	Pathogenic	0.189
BRCA1	P38398-1.2	F1772R	Pathogenic	0.189
BRCA1	P38398-1.2	F1772S	Pathogenic	0.232
BRCA1	P38398-1.2	F1772T	Pathogenic	0.232
BRCA1	P38398-1.2	F1772V	Pathogenic	0.274
BRCA1	P38398-1.2	F1772W	Pathogenic	0.359
BRCA1	P38398-1.2	F1772Y	Pathogenic	0.444
BRCA1	P38398-1.2	T1773A	Neutral	0.55
BRCA1	P38398-1.2	T1773C	Pathogenic	0.508
BRCA1	P38398-1.2	T1773D	Pathogenic	0.508
BRCA1	P38398-1.2	T1773E	Pathogenic	0.508
BRCA1	P38398-1.2	T1773F	Pathogenic	0.465
BRCA1	P38398-1.2	T1773G	Pathogenic	0.465
BRCA1	P38398-1.2	T1773H	Pathogenic	0.465
BRCA1	P38398-1.2	T1773I	Pathogenic	0.508
BRCA1	P38398-1.2	T1773K	Pathogenic	0.508
BRCA1	P38398-1.2	T1773L	Pathogenic	0.508
BRCA1	P38398-1.2	T1773M	Pathogenic	0.508
BRCA1	P38398-1.2	T1773N	Neutral	0.55
BRCA1	P38398-1.2	T1773P	Pathogenic	0.508
BRCA1	P38398-1.2	T1773Q	Pathogenic	0.508
BRCA1	P38398-1.2	T1773R	Pathogenic	0.508
BRCA1	P38398-1.2	T1773S	Neutral	0.593
BRCA1	P38398-1.2	T1773V	Neutral	0.55
BRCA1	P38398-1.2	T1773W	Pathogenic	0.465
BRCA1	P38398-1.2	T1773Y	Pathogenic	0.465
BRCA1	P38398-1.2	N1774A	Neutral	0.87
BRCA1	P38398-1.2	N1774C	Neutral	0.827
BRCA1	P38398-1.2	N1774D	Neutral	0.998
BRCA1	P38398-1.2	N1774E	Neutral	0.955
BRCA1	P38398-1.2	N1774F	Neutral	0.827
BRCA1	P38398-1.2	N1774G	Neutral	0.955
BRCA1	P38398-1.2	N1774H	Neutral	0.998
BRCA1	P38398-1.2	N1774I	Neutral	0.827
BRCA1	P38398-1.2	N1774K	Neutral	0.955
BRCA1	P38398-1.2	N1774L	Neutral	0.827
BRCA1	P38398-1.2	N1774M	Neutral	0.87
BRCA1	P38398-1.2	N1774P	Neutral	0.87
BRCA1	P38398-1.2	N1774Q	Neutral	0.955
BRCA1	P38398-1.2	N1774R	Neutral	0.955
BRCA1	P38398-1.2	N1774S	Neutral	0.998
BRCA1	P38398-1.2	N1774T	Neutral	0.955
BRCA1	P38398-1.2	N1774V	Neutral	0.827
BRCA1	P38398-1.2	N1774W	Neutral	0.785
BRCA1	P38398-1.2	N1774Y	Neutral	0.87
BRCA1	P38398-1.2	M1775A	Pathogenic	0.332
BRCA1	P38398-1.2	M1775C	Pathogenic	0.332
BRCA1	P38398-1.2	M1775D	Pathogenic	0.247
BRCA1	P38398-1.2	M1775E	Pathogenic	0.29
BRCA1	P38398-1.2	M1775F	Pathogenic	0.375
BRCA1	P38398-1.2	M1775G	Pathogenic	0.247
BRCA1	P38398-1.2	M1775H	Pathogenic	0.29
BRCA1	P38398-1.2	M1775I	Pathogenic	0.418
BRCA1	P38398-1.2	M1775K	Pathogenic	0.332
BRCA1	P38398-1.2	M1775L	Pathogenic	0.46
BRCA1	P38398-1.2	M1775N	Pathogenic	0.29
BRCA1	P38398-1.2	M1775P	Pathogenic	0.29
BRCA1	P38398-1.2	M1775Q	Pathogenic	0.375
BRCA1	P38398-1.2	M1775R	Pathogenic	0.332
BRCA1	P38398-1.2	M1775S	Pathogenic	0.332
BRCA1	P38398-1.2	M1775T	Pathogenic	0.332
BRCA1	P38398-1.2	M1775V	Pathogenic	0.418
BRCA1	P38398-1.2	M1775W	Pathogenic	0.332
BRCA1	P38398-1.2	M1775Y	Pathogenic	0.332
BRCA1	P38398-1.2	P1776A	Neutral	0.945
BRCA1	P38398-1.2	P1776C	Neutral	0.86
BRCA1	P38398-1.2	P1776D	Neutral	0.945
BRCA1	P38398-1.2	P1776E	Neutral	0.945
BRCA1	P38398-1.2	P1776F	Neutral	0.818
BRCA1	P38398-1.2	P1776G	Neutral	0.903
BRCA1	P38398-1.2	P1776H	Neutral	0.903
BRCA1	P38398-1.2	P1776I	Neutral	0.86
BRCA1	P38398-1.2	P1776K	Neutral	0.945
BRCA1	P38398-1.2	P1776L	Neutral	0.86
BRCA1	P38398-1.2	P1776M	Neutral	0.903
BRCA1	P38398-1.2	P1776N	Neutral	0.903
BRCA1	P38398-1.2	P1776Q	Neutral	0.945
BRCA1	P38398-1.2	P1776R	Neutral	0.903
BRCA1	P38398-1.2	P1776S	Neutral	0.945
BRCA1	P38398-1.2	P1776T	Neutral	0.945
BRCA1	P38398-1.2	P1776V	Neutral	0.903
BRCA1	P38398-1.2	P1776W	Neutral	0.818
BRCA1	P38398-1.2	P1776Y	Neutral	0.86
BRCA1	P38398-1.2	T1777A	Neutral	0.871
BRCA1	P38398-1.2	T1777C	Neutral	0.828
BRCA1	P38398-1.2	T1777D	Neutral	0.828
BRCA1	P38398-1.2	T1777E	Neutral	0.828
BRCA1	P38398-1.2	T1777F	Neutral	0.785
BRCA1	P38398-1.2	T1777G	Neutral	0.785
BRCA1	P38398-1.2	T1777H	Neutral	0.785
BRCA1	P38398-1.2	T1777I	Neutral	0.828
BRCA1	P38398-1.2	T1777K	Neutral	0.828
BRCA1	P38398-1.2	T1777L	Neutral	0.828
BRCA1	P38398-1.2	T1777M	Neutral	0.828
BRCA1	P38398-1.2	T1777N	Neutral	0.871
BRCA1	P38398-1.2	T1777P	Neutral	0.828
BRCA1	P38398-1.2	T1777Q	Neutral	0.828
BRCA1	P38398-1.2	T1777R	Neutral	0.828
BRCA1	P38398-1.2	T1777S	Neutral	0.913
BRCA1	P38398-1.2	T1777V	Neutral	0.871
BRCA1	P38398-1.2	T1777W	Neutral	0.785
BRCA1	P38398-1.2	T1777Y	Neutral	0.785
BRCA1	P38398-1.2	D1778A	Neutral	0.655
BRCA1	P38398-1.2	D1778C	Neutral	0.612
BRCA1	P38398-1.2	D1778E	Neutral	0.825
BRCA1	P38398-1.2	D1778F	Neutral	0.612
BRCA1	P38398-1.2	D1778G	Neutral	0.697
BRCA1	P38398-1.2	D1778H	Neutral	0.697
BRCA1	P38398-1.2	D1778I	Neutral	0.612
BRCA1	P38398-1.2	D1778K	Neutral	0.697
BRCA1	P38398-1.2	D1778L	Neutral	0.57
BRCA1	P38398-1.2	D1778M	Neutral	0.612
BRCA1	P38398-1.2	D1778N	Neutral	0.783
BRCA1	P38398-1.2	D1778P	Neutral	0.697
BRCA1	P38398-1.2	D1778Q	Neutral	0.74
BRCA1	P38398-1.2	D1778R	Neutral	0.655
BRCA1	P38398-1.2	D1778S	Neutral	0.74
BRCA1	P38398-1.2	D1778T	Neutral	0.697
BRCA1	P38398-1.2	D1778V	Neutral	0.612
BRCA1	P38398-1.2	D1778W	Neutral	0.57
BRCA1	P38398-1.2	D1778Y	Neutral	0.612
BRCA1	P38398-1.2	Q1779A	Neutral	0.873
BRCA1	P38398-1.2	Q1779C	Neutral	0.788
BRCA1	P38398-1.2	Q1779D	Neutral	0.916
BRCA1	P38398-1.2	Q1779E	Neutral	1.001
BRCA1	P38398-1.2	Q1779F	Neutral	0.788
BRCA1	P38398-1.2	Q1779G	Neutral	0.831
BRCA1	P38398-1.2	Q1779H	Neutral	0.916
BRCA1	P38398-1.2	Q1779I	Neutral	0.788
BRCA1	P38398-1.2	Q1779K	Neutral	0.958
BRCA1	P38398-1.2	Q1779L	Neutral	0.831
BRCA1	P38398-1.2	Q1779M	Neutral	0.916
BRCA1	P38398-1.2	Q1779N	Neutral	0.916
BRCA1	P38398-1.2	Q1779P	Neutral	0.873
BRCA1	P38398-1.2	Q1779R	Neutral	0.958
BRCA1	P38398-1.2	Q1779S	Neutral	0.916
BRCA1	P38398-1.2	Q1779T	Neutral	0.873
BRCA1	P38398-1.2	Q1779V	Neutral	0.831
BRCA1	P38398-1.2	Q1779W	Neutral	0.831
BRCA1	P38398-1.2	Q1779Y	Neutral	0.873
BRCA1	P38398-1.2	L1780A	Neutral	0.703
BRCA1	P38398-1.2	L1780C	Neutral	0.703
BRCA1	P38398-1.2	L1780D	Neutral	0.576
BRCA1	P38398-1.2	L1780E	Neutral	0.618
BRCA1	P38398-1.2	L1780F	Neutral	0.746
BRCA1	P38398-1.2	L1780G	Neutral	0.576
BRCA1	P38398-1.2	L1780H	Neutral	0.618
BRCA1	P38398-1.2	L1780I	Neutral	0.831
BRCA1	P38398-1.2	L1780K	Neutral	0.661
BRCA1	P38398-1.2	L1780M	Neutral	0.831
BRCA1	P38398-1.2	L1780N	Neutral	0.618
BRCA1	P38398-1.2	L1780P	Neutral	0.618
BRCA1	P38398-1.2	L1780Q	Neutral	0.661
BRCA1	P38398-1.2	L1780R	Neutral	0.661
BRCA1	P38398-1.2	L1780S	Neutral	0.661
BRCA1	P38398-1.2	L1780T	Neutral	0.703
BRCA1	P38398-1.2	L1780V	Neutral	0.789
BRCA1	P38398-1.2	L1780W	Neutral	0.661
BRCA1	P38398-1.2	L1780Y	Neutral	0.703
BRCA1	P38398-1.2	E1781A	Neutral	0.82
BRCA1	P38398-1.2	E1781C	Neutral	0.692
BRCA1	P38398-1.2	E1781D	Neutral	0.947
BRCA1	P38398-1.2	E1781F	Neutral	0.734
BRCA1	P38398-1.2	E1781G	Neutral	0.777
BRCA1	P38398-1.2	E1781H	Neutral	0.862
BRCA1	P38398-1.2	E1781I	Neutral	0.734
BRCA1	P38398-1.2	E1781K	Neutral	0.905
BRCA1	P38398-1.2	E1781L	Neutral	0.734
BRCA1	P38398-1.2	E1781M	Neutral	0.777
BRCA1	P38398-1.2	E1781N	Neutral	0.862
BRCA1	P38398-1.2	E1781P	Neutral	0.82
BRCA1	P38398-1.2	E1781Q	Neutral	0.947
BRCA1	P38398-1.2	E1781R	Neutral	0.862
BRCA1	P38398-1.2	E1781S	Neutral	0.862
BRCA1	P38398-1.2	E1781T	Neutral	0.82
BRCA1	P38398-1.2	E1781V	Neutral	0.777
BRCA1	P38398-1.2	E1781W	Neutral	0.734
BRCA1	P38398-1.2	E1781Y	Neutral	0.777
BRCA1	P38398-1.2	W1782A	Pathogenic	0.112
BRCA1	P38398-1.2	W1782C	Pathogenic	0.155
BRCA1	P38398-1.2	W1782D	Pathogenic	0.07
BRCA1	P38398-1.2	W1782E	Pathogenic	0.112
BRCA1	P38398-1.2	W1782F	Pathogenic	0.283
BRCA1	P38398-1.2	W1782G	Pathogenic	0.155
BRCA1	P38398-1.2	W1782H	Pathogenic	0.155
BRCA1	P38398-1.2	W1782I	Pathogenic	0.112
BRCA1	P38398-1.2	W1782K	Pathogenic	0.112
BRCA1	P38398-1.2	W1782L	Pathogenic	0.155
BRCA1	P38398-1.2	W1782M	Pathogenic	0.197
BRCA1	P38398-1.2	W1782N	Pathogenic	0.07
BRCA1	P38398-1.2	W1782P	Pathogenic	0.07
BRCA1	P38398-1.2	W1782Q	Pathogenic	0.155
BRCA1	P38398-1.2	W1782R	Pathogenic	0.112
BRCA1	P38398-1.2	W1782S	Pathogenic	0.112
BRCA1	P38398-1.2	W1782T	Pathogenic	0.155
BRCA1	P38398-1.2	W1782V	Pathogenic	0.112
BRCA1	P38398-1.2	W1782Y	Pathogenic	0.325
BRCA1	P38398-1.2	M1783A	Pathogenic	0.477
BRCA1	P38398-1.2	M1783C	Pathogenic	0.477
BRCA1	P38398-1.2	M1783D	Pathogenic	0.391
BRCA1	P38398-1.2	M1783E	Pathogenic	0.434
BRCA1	P38398-1.2	M1783F	Pathogenic	0.519
BRCA1	P38398-1.2	M1783G	Pathogenic	0.391
BRCA1	P38398-1.2	M1783H	Pathogenic	0.434
BRCA1	P38398-1.2	M1783I	Neutral	0.562
BRCA1	P38398-1.2	M1783K	Pathogenic	0.477
BRCA1	P38398-1.2	M1783L	Neutral	0.604
BRCA1	P38398-1.2	M1783N	Pathogenic	0.434
BRCA1	P38398-1.2	M1783P	Pathogenic	0.434
BRCA1	P38398-1.2	M1783Q	Pathogenic	0.519
BRCA1	P38398-1.2	M1783R	Pathogenic	0.477
BRCA1	P38398-1.2	M1783S	Pathogenic	0.477
BRCA1	P38398-1.2	M1783T	Pathogenic	0.477
BRCA1	P38398-1.2	M1783V	Neutral	0.562
BRCA1	P38398-1.2	M1783W	Pathogenic	0.477
BRCA1	P38398-1.2	M1783Y	Pathogenic	0.477
BRCA1	P38398-1.2	V1784A	Neutral	0.793
BRCA1	P38398-1.2	V1784C	Neutral	0.75
BRCA1	P38398-1.2	V1784D	Neutral	0.665
BRCA1	P38398-1.2	V1784E	Neutral	0.708
BRCA1	P38398-1.2	V1784F	Neutral	0.75
BRCA1	P38398-1.2	V1784G	Neutral	0.665
BRCA1	P38398-1.2	V1784H	Neutral	0.665
BRCA1	P38398-1.2	V1784I	Neutral	0.921
BRCA1	P38398-1.2	V1784K	Neutral	0.708
BRCA1	P38398-1.2	V1784L	Neutral	0.836
BRCA1	P38398-1.2	V1784M	Neutral	0.836
BRCA1	P38398-1.2	V1784N	Neutral	0.665
BRCA1	P38398-1.2	V1784P	Neutral	0.708
BRCA1	P38398-1.2	V1784Q	Neutral	0.708
BRCA1	P38398-1.2	V1784R	Neutral	0.665
BRCA1	P38398-1.2	V1784S	Neutral	0.708
BRCA1	P38398-1.2	V1784T	Neutral	0.793
BRCA1	P38398-1.2	V1784W	Neutral	0.665
BRCA1	P38398-1.2	V1784Y	Neutral	0.75
BRCA1	P38398-1.2	Q1785A	Neutral	0.913
BRCA1	P38398-1.2	Q1785C	Neutral	0.828
BRCA1	P38398-1.2	Q1785D	Neutral	0.956
BRCA1	P38398-1.2	Q1785E	Neutral	1.041
BRCA1	P38398-1.2	Q1785F	Neutral	0.828
BRCA1	P38398-1.2	Q1785G	Neutral	0.871
BRCA1	P38398-1.2	Q1785H	Neutral	0.956
BRCA1	P38398-1.2	Q1785I	Neutral	0.828
BRCA1	P38398-1.2	Q1785K	Neutral	0.998
BRCA1	P38398-1.2	Q1785L	Neutral	0.871
BRCA1	P38398-1.2	Q1785M	Neutral	0.956
BRCA1	P38398-1.2	Q1785N	Neutral	0.956
BRCA1	P38398-1.2	Q1785P	Neutral	0.913
BRCA1	P38398-1.2	Q1785R	Neutral	0.998
BRCA1	P38398-1.2	Q1785S	Neutral	0.956
BRCA1	P38398-1.2	Q1785T	Neutral	0.913
BRCA1	P38398-1.2	Q1785V	Neutral	0.871
BRCA1	P38398-1.2	Q1785W	Neutral	0.871
BRCA1	P38398-1.2	Q1785Y	Neutral	0.913
BRCA1	P38398-1.2	L1786A	Neutral	0.863
BRCA1	P38398-1.2	L1786C	Neutral	0.863
BRCA1	P38398-1.2	L1786D	Neutral	0.735
BRCA1	P38398-1.2	L1786E	Neutral	0.777
BRCA1	P38398-1.2	L1786F	Neutral	0.905
BRCA1	P38398-1.2	L1786G	Neutral	0.735
BRCA1	P38398-1.2	L1786H	Neutral	0.777
BRCA1	P38398-1.2	L1786I	Neutral	0.99
BRCA1	P38398-1.2	L1786K	Neutral	0.82
BRCA1	P38398-1.2	L1786M	Neutral	0.99
BRCA1	P38398-1.2	L1786N	Neutral	0.777
BRCA1	P38398-1.2	L1786P	Neutral	0.777
BRCA1	P38398-1.2	L1786Q	Neutral	0.82
BRCA1	P38398-1.2	L1786R	Neutral	0.82
BRCA1	P38398-1.2	L1786S	Neutral	0.82
BRCA1	P38398-1.2	L1786T	Neutral	0.863
BRCA1	P38398-1.2	L1786V	Neutral	0.948
BRCA1	P38398-1.2	L1786W	Neutral	0.82
BRCA1	P38398-1.2	L1786Y	Neutral	0.863
BRCA1	P38398-1.2	C1787A	Pathogenic	0.3
BRCA1	P38398-1.2	C1787D	Pathogenic	0.173
BRCA1	P38398-1.2	C1787E	Pathogenic	0.13
BRCA1	P38398-1.2	C1787F	Pathogenic	0.215
BRCA1	P38398-1.2	C1787G	Pathogenic	0.173
BRCA1	P38398-1.2	C1787H	Pathogenic	0.173
BRCA1	P38398-1.2	C1787I	Pathogenic	0.258
BRCA1	P38398-1.2	C1787K	Pathogenic	0.173
BRCA1	P38398-1.2	C1787L	Pathogenic	0.258
BRCA1	P38398-1.2	C1787M	Pathogenic	0.258
BRCA1	P38398-1.2	C1787N	Pathogenic	0.173
BRCA1	P38398-1.2	C1787P	Pathogenic	0.173
BRCA1	P38398-1.2	C1787Q	Pathogenic	0.173
BRCA1	P38398-1.2	C1787R	Pathogenic	0.173
BRCA1	P38398-1.2	C1787S	Pathogenic	0.258
BRCA1	P38398-1.2	C1787T	Pathogenic	0.258
BRCA1	P38398-1.2	C1787V	Pathogenic	0.258
BRCA1	P38398-1.2	C1787W	Pathogenic	0.215
BRCA1	P38398-1.2	C1787Y	Pathogenic	0.215
BRCA1	P38398-1.2	G1788A	Pathogenic	0.497
BRCA1	P38398-1.2	G1788C	Pathogenic	0.369
BRCA1	P38398-1.2	G1788D	Pathogenic	0.455
BRCA1	P38398-1.2	G1788E	Pathogenic	0.412
BRCA1	P38398-1.2	G1788F	Pathogenic	0.369
BRCA1	P38398-1.2	G1788H	Pathogenic	0.412
BRCA1	P38398-1.2	G1788I	Pathogenic	0.327
BRCA1	P38398-1.2	G1788K	Pathogenic	0.412
BRCA1	P38398-1.2	G1788L	Pathogenic	0.327
BRCA1	P38398-1.2	G1788M	Pathogenic	0.369
BRCA1	P38398-1.2	G1788N	Pathogenic	0.497
BRCA1	P38398-1.2	G1788P	Pathogenic	0.412
BRCA1	P38398-1.2	G1788Q	Pathogenic	0.412
BRCA1	P38398-1.2	G1788R	Pathogenic	0.412
BRCA1	P38398-1.2	G1788S	Pathogenic	0.497
BRCA1	P38398-1.2	G1788T	Pathogenic	0.412
BRCA1	P38398-1.2	G1788V	Pathogenic	0.369
BRCA1	P38398-1.2	G1788W	Pathogenic	0.412
BRCA1	P38398-1.2	G1788Y	Pathogenic	0.369
BRCA1	P38398-1.2	A1789C	Pathogenic	0.502
BRCA1	P38398-1.2	A1789D	Pathogenic	0.417
BRCA1	P38398-1.2	A1789E	Pathogenic	0.46
BRCA1	P38398-1.2	A1789F	Pathogenic	0.417
BRCA1	P38398-1.2	A1789G	Pathogenic	0.502
BRCA1	P38398-1.2	A1789H	Pathogenic	0.417
BRCA1	P38398-1.2	A1789I	Pathogenic	0.46
BRCA1	P38398-1.2	A1789K	Pathogenic	0.46
BRCA1	P38398-1.2	A1789L	Pathogenic	0.46
BRCA1	P38398-1.2	A1789M	Pathogenic	0.46
BRCA1	P38398-1.2	A1789N	Pathogenic	0.417
BRCA1	P38398-1.2	A1789P	Pathogenic	0.46
BRCA1	P38398-1.2	A1789Q	Pathogenic	0.46
BRCA1	P38398-1.2	A1789R	Pathogenic	0.46
BRCA1	P38398-1.2	A1789S	Neutral	0.545
BRCA1	P38398-1.2	A1789T	Pathogenic	0.502
BRCA1	P38398-1.2	A1789V	Pathogenic	0.502
BRCA1	P38398-1.2	A1789W	Pathogenic	0.375
BRCA1	P38398-1.2	A1789Y	Pathogenic	0.417
BRCA1	P38398-1.2	S1790A	Neutral	0.976
BRCA1	P38398-1.2	S1790C	Neutral	0.89
BRCA1	P38398-1.2	S1790D	Neutral	0.933
BRCA1	P38398-1.2	S1790E	Neutral	0.933
BRCA1	P38398-1.2	S1790F	Neutral	0.848
BRCA1	P38398-1.2	S1790G	Neutral	0.933
BRCA1	P38398-1.2	S1790H	Neutral	0.89
BRCA1	P38398-1.2	S1790I	Neutral	0.848
BRCA1	P38398-1.2	S1790K	Neutral	0.933
BRCA1	P38398-1.2	S1790L	Neutral	0.848
BRCA1	P38398-1.2	S1790M	Neutral	0.89
BRCA1	P38398-1.2	S1790N	Neutral	0.976
BRCA1	P38398-1.2	S1790P	Neutral	0.89
BRCA1	P38398-1.2	S1790Q	Neutral	0.933
BRCA1	P38398-1.2	S1790R	Neutral	0.89
BRCA1	P38398-1.2	S1790T	Neutral	0.976
BRCA1	P38398-1.2	S1790V	Neutral	0.848
BRCA1	P38398-1.2	S1790W	Neutral	0.805
BRCA1	P38398-1.2	S1790Y	Neutral	0.848
BRCA1	P38398-1.2	V1791A	Neutral	0.708
BRCA1	P38398-1.2	V1791C	Neutral	0.665
BRCA1	P38398-1.2	V1791D	Neutral	0.58
BRCA1	P38398-1.2	V1791E	Neutral	0.623
BRCA1	P38398-1.2	V1791F	Neutral	0.665
BRCA1	P38398-1.2	V1791G	Neutral	0.58
BRCA1	P38398-1.2	V1791H	Neutral	0.58
BRCA1	P38398-1.2	V1791I	Neutral	0.836
BRCA1	P38398-1.2	V1791K	Neutral	0.623
BRCA1	P38398-1.2	V1791L	Neutral	0.751
BRCA1	P38398-1.2	V1791M	Neutral	0.751
BRCA1	P38398-1.2	V1791N	Neutral	0.58
BRCA1	P38398-1.2	V1791P	Neutral	0.623
BRCA1	P38398-1.2	V1791Q	Neutral	0.623
BRCA1	P38398-1.2	V1791R	Neutral	0.58
BRCA1	P38398-1.2	V1791S	Neutral	0.623
BRCA1	P38398-1.2	V1791T	Neutral	0.708
BRCA1	P38398-1.2	V1791W	Neutral	0.58
BRCA1	P38398-1.2	V1791Y	Neutral	0.665
BRCA1	P38398-1.2	V1792A	Neutral	0.533
BRCA1	P38398-1.2	V1792C	Pathogenic	0.491
BRCA1	P38398-1.2	V1792D	Pathogenic	0.406
BRCA1	P38398-1.2	V1792E	Pathogenic	0.448
BRCA1	P38398-1.2	V1792F	Pathogenic	0.491
BRCA1	P38398-1.2	V1792G	Pathogenic	0.406
BRCA1	P38398-1.2	V1792H	Pathogenic	0.406
BRCA1	P38398-1.2	V1792I	Neutral	0.661
BRCA1	P38398-1.2	V1792K	Pathogenic	0.448
BRCA1	P38398-1.2	V1792L	Neutral	0.576
BRCA1	P38398-1.2	V1792M	Neutral	0.576
BRCA1	P38398-1.2	V1792N	Pathogenic	0.406
BRCA1	P38398-1.2	V1792P	Pathogenic	0.448
BRCA1	P38398-1.2	V1792Q	Pathogenic	0.448
BRCA1	P38398-1.2	V1792R	Pathogenic	0.406
BRCA1	P38398-1.2	V1792S	Pathogenic	0.448
BRCA1	P38398-1.2	V1792T	Neutral	0.533
BRCA1	P38398-1.2	V1792W	Pathogenic	0.406
BRCA1	P38398-1.2	V1792Y	Pathogenic	0.491
BRCA1	P38398-1.2	K1793A	Neutral	0.79
BRCA1	P38398-1.2	K1793C	Neutral	0.705
BRCA1	P38398-1.2	K1793D	Neutral	0.79
BRCA1	P38398-1.2	K1793E	Neutral	0.876
BRCA1	P38398-1.2	K1793F	Neutral	0.705
BRCA1	P38398-1.2	K1793G	Neutral	0.748
BRCA1	P38398-1.2	K1793H	Neutral	0.79
BRCA1	P38398-1.2	K1793I	Neutral	0.705
BRCA1	P38398-1.2	K1793L	Neutral	0.748
BRCA1	P38398-1.2	K1793M	Neutral	0.79
BRCA1	P38398-1.2	K1793N	Neutral	0.833
BRCA1	P38398-1.2	K1793P	Neutral	0.79
BRCA1	P38398-1.2	K1793Q	Neutral	0.876
BRCA1	P38398-1.2	K1793R	Neutral	0.918
BRCA1	P38398-1.2	K1793S	Neutral	0.833
BRCA1	P38398-1.2	K1793T	Neutral	0.79
BRCA1	P38398-1.2	K1793V	Neutral	0.748
BRCA1	P38398-1.2	K1793W	Neutral	0.705
BRCA1	P38398-1.2	K1793Y	Neutral	0.748
BRCA1	P38398-1.2	E1794A	Neutral	1.184
BRCA1	P38398-1.2	E1794C	Neutral	1.056
BRCA1	P38398-1.2	E1794D	Neutral	1.311
BRCA1	P38398-1.2	E1794F	Neutral	1.099
BRCA1	P38398-1.2	E1794G	Neutral	1.141
BRCA1	P38398-1.2	E1794H	Neutral	1.226
BRCA1	P38398-1.2	E1794I	Neutral	1.099
BRCA1	P38398-1.2	E1794K	Neutral	1.269
BRCA1	P38398-1.2	E1794L	Neutral	1.099
BRCA1	P38398-1.2	E1794M	Neutral	1.141
BRCA1	P38398-1.2	E1794N	Neutral	1.226
BRCA1	P38398-1.2	E1794P	Neutral	1.184
BRCA1	P38398-1.2	E1794Q	Neutral	1.311
BRCA1	P38398-1.2	E1794R	Neutral	1.226
BRCA1	P38398-1.2	E1794S	Neutral	1.226
BRCA1	P38398-1.2	E1794T	Neutral	1.184
BRCA1	P38398-1.2	E1794V	Neutral	1.141
BRCA1	P38398-1.2	E1794W	Neutral	1.099
BRCA1	P38398-1.2	E1794Y	Neutral	1.141
BRCA1	P38398-1.2	L1795A	Neutral	0.902
BRCA1	P38398-1.2	L1795C	Neutral	0.902
BRCA1	P38398-1.2	L1795D	Neutral	0.774
BRCA1	P38398-1.2	L1795E	Neutral	0.816
BRCA1	P38398-1.2	L1795F	Neutral	0.944
BRCA1	P38398-1.2	L1795G	Neutral	0.774
BRCA1	P38398-1.2	L1795H	Neutral	0.816
BRCA1	P38398-1.2	L1795I	Neutral	1.029
BRCA1	P38398-1.2	L1795K	Neutral	0.859
BRCA1	P38398-1.2	L1795M	Neutral	1.029
BRCA1	P38398-1.2	L1795N	Neutral	0.816
BRCA1	P38398-1.2	L1795P	Neutral	0.816
BRCA1	P38398-1.2	L1795Q	Neutral	0.859
BRCA1	P38398-1.2	L1795R	Neutral	0.859
BRCA1	P38398-1.2	L1795S	Neutral	0.859
BRCA1	P38398-1.2	L1795T	Neutral	0.902
BRCA1	P38398-1.2	L1795V	Neutral	0.987
BRCA1	P38398-1.2	L1795W	Neutral	0.859
BRCA1	P38398-1.2	L1795Y	Neutral	0.902
BRCA1	P38398-1.2	S1796A	Neutral	1.211
BRCA1	P38398-1.2	S1796C	Neutral	1.126
BRCA1	P38398-1.2	S1796D	Neutral	1.168
BRCA1	P38398-1.2	S1796E	Neutral	1.168
BRCA1	P38398-1.2	S1796F	Neutral	1.083
BRCA1	P38398-1.2	S1796G	Neutral	1.168
BRCA1	P38398-1.2	S1796H	Neutral	1.126
BRCA1	P38398-1.2	S1796I	Neutral	1.083
BRCA1	P38398-1.2	S1796K	Neutral	1.168
BRCA1	P38398-1.2	S1796L	Neutral	1.083
BRCA1	P38398-1.2	S1796M	Neutral	1.126
BRCA1	P38398-1.2	S1796N	Neutral	1.211
BRCA1	P38398-1.2	S1796P	Neutral	1.126
BRCA1	P38398-1.2	S1796Q	Neutral	1.168
BRCA1	P38398-1.2	S1796R	Neutral	1.126
BRCA1	P38398-1.2	S1796T	Neutral	1.211
BRCA1	P38398-1.2	S1796V	Neutral	1.083
BRCA1	P38398-1.2	S1796W	Neutral	1.041
BRCA1	P38398-1.2	S1796Y	Neutral	1.083
BRCA1	P38398-1.2	S1797A	Neutral	1.174
BRCA1	P38398-1.2	S1797C	Neutral	1.089
BRCA1	P38398-1.2	S1797D	Neutral	1.131
BRCA1	P38398-1.2	S1797E	Neutral	1.131
BRCA1	P38398-1.2	S1797F	Neutral	1.046
BRCA1	P38398-1.2	S1797G	Neutral	1.131
BRCA1	P38398-1.2	S1797H	Neutral	1.089
BRCA1	P38398-1.2	S1797I	Neutral	1.046
BRCA1	P38398-1.2	S1797K	Neutral	1.131
BRCA1	P38398-1.2	S1797L	Neutral	1.046
BRCA1	P38398-1.2	S1797M	Neutral	1.089
BRCA1	P38398-1.2	S1797N	Neutral	1.174
BRCA1	P38398-1.2	S1797P	Neutral	1.089
BRCA1	P38398-1.2	S1797Q	Neutral	1.131
BRCA1	P38398-1.2	S1797R	Neutral	1.089
BRCA1	P38398-1.2	S1797T	Neutral	1.174
BRCA1	P38398-1.2	S1797V	Neutral	1.046
BRCA1	P38398-1.2	S1797W	Neutral	1.003
BRCA1	P38398-1.2	S1797Y	Neutral	1.046
BRCA1	P38398-1.2	F1798A	Pathogenic	0.459
BRCA1	P38398-1.2	F1798C	Pathogenic	0.459
BRCA1	P38398-1.2	F1798D	Pathogenic	0.416
BRCA1	P38398-1.2	F1798E	Pathogenic	0.416
BRCA1	P38398-1.2	F1798G	Pathogenic	0.416
BRCA1	P38398-1.2	F1798H	Pathogenic	0.502
BRCA1	P38398-1.2	F1798I	Neutral	0.544
BRCA1	P38398-1.2	F1798K	Pathogenic	0.416
BRCA1	P38398-1.2	F1798L	Neutral	0.544
BRCA1	P38398-1.2	F1798M	Neutral	0.544
BRCA1	P38398-1.2	F1798N	Pathogenic	0.416
BRCA1	P38398-1.2	F1798P	Pathogenic	0.374
BRCA1	P38398-1.2	F1798Q	Pathogenic	0.416
BRCA1	P38398-1.2	F1798R	Pathogenic	0.416
BRCA1	P38398-1.2	F1798S	Pathogenic	0.459
BRCA1	P38398-1.2	F1798T	Pathogenic	0.459
BRCA1	P38398-1.2	F1798V	Pathogenic	0.502
BRCA1	P38398-1.2	F1798W	Neutral	0.587
BRCA1	P38398-1.2	F1798Y	Neutral	0.672
BRCA1	P38398-1.2	T1799A	Neutral	1.027
BRCA1	P38398-1.2	T1799C	Neutral	0.985
BRCA1	P38398-1.2	T1799D	Neutral	0.985
BRCA1	P38398-1.2	T1799E	Neutral	0.985
BRCA1	P38398-1.2	T1799F	Neutral	0.942
BRCA1	P38398-1.2	T1799G	Neutral	0.942
BRCA1	P38398-1.2	T1799H	Neutral	0.942
BRCA1	P38398-1.2	T1799I	Neutral	0.985
BRCA1	P38398-1.2	T1799K	Neutral	0.985
BRCA1	P38398-1.2	T1799L	Neutral	0.985
BRCA1	P38398-1.2	T1799M	Neutral	0.985
BRCA1	P38398-1.2	T1799N	Neutral	1.027
BRCA1	P38398-1.2	T1799P	Neutral	0.985
BRCA1	P38398-1.2	T1799Q	Neutral	0.985
BRCA1	P38398-1.2	T1799R	Neutral	0.985
BRCA1	P38398-1.2	T1799S	Neutral	1.07
BRCA1	P38398-1.2	T1799V	Neutral	1.027
BRCA1	P38398-1.2	T1799W	Neutral	0.942
BRCA1	P38398-1.2	T1799Y	Neutral	0.942
BRCA1	P38398-1.2	L1800A	Neutral	1.285
BRCA1	P38398-1.2	L1800C	Neutral	1.285
BRCA1	P38398-1.2	L1800D	Neutral	1.157
BRCA1	P38398-1.2	L1800E	Neutral	1.2
BRCA1	P38398-1.2	L1800F	Neutral	1.328
BRCA1	P38398-1.2	L1800G	Neutral	1.157
BRCA1	P38398-1.2	L1800H	Neutral	1.2
BRCA1	P38398-1.2	L1800I	Neutral	1.413
BRCA1	P38398-1.2	L1800K	Neutral	1.243
BRCA1	P38398-1.2	L1800M	Neutral	1.413
BRCA1	P38398-1.2	L1800N	Neutral	1.2
BRCA1	P38398-1.2	L1800P	Neutral	1.2
BRCA1	P38398-1.2	L1800Q	Neutral	1.243
BRCA1	P38398-1.2	L1800R	Neutral	1.243
BRCA1	P38398-1.2	L1800S	Neutral	1.243
BRCA1	P38398-1.2	L1800T	Neutral	1.285
BRCA1	P38398-1.2	L1800V	Neutral	1.37
BRCA1	P38398-1.2	L1800W	Neutral	1.243
BRCA1	P38398-1.2	L1800Y	Neutral	1.285
BRCA1	P38398-1.2	G1801A	Neutral	1.196
BRCA1	P38398-1.2	G1801C	Neutral	1.068
BRCA1	P38398-1.2	G1801D	Neutral	1.153
BRCA1	P38398-1.2	G1801E	Neutral	1.11
BRCA1	P38398-1.2	G1801F	Neutral	1.068
BRCA1	P38398-1.2	G1801H	Neutral	1.11
BRCA1	P38398-1.2	G1801I	Neutral	1.025
BRCA1	P38398-1.2	G1801K	Neutral	1.11
BRCA1	P38398-1.2	G1801L	Neutral	1.025
BRCA1	P38398-1.2	G1801M	Neutral	1.068
BRCA1	P38398-1.2	G1801N	Neutral	1.196
BRCA1	P38398-1.2	G1801P	Neutral	1.11
BRCA1	P38398-1.2	G1801Q	Neutral	1.11
BRCA1	P38398-1.2	G1801R	Neutral	1.11
BRCA1	P38398-1.2	G1801S	Neutral	1.196
BRCA1	P38398-1.2	G1801T	Neutral	1.11
BRCA1	P38398-1.2	G1801V	Neutral	1.068
BRCA1	P38398-1.2	G1801W	Neutral	1.11
BRCA1	P38398-1.2	G1801Y	Neutral	1.068
BRCA1	P38398-1.2	T1802A	Neutral	1.244
BRCA1	P38398-1.2	T1802C	Neutral	1.202
BRCA1	P38398-1.2	T1802D	Neutral	1.202
BRCA1	P38398-1.2	T1802E	Neutral	1.202
BRCA1	P38398-1.2	T1802F	Neutral	1.159
BRCA1	P38398-1.2	T1802G	Neutral	1.159
BRCA1	P38398-1.2	T1802H	Neutral	1.159
BRCA1	P38398-1.2	T1802I	Neutral	1.202
BRCA1	P38398-1.2	T1802K	Neutral	1.202
BRCA1	P38398-1.2	T1802L	Neutral	1.202
BRCA1	P38398-1.2	T1802M	Neutral	1.202
BRCA1	P38398-1.2	T1802N	Neutral	1.244
BRCA1	P38398-1.2	T1802P	Neutral	1.202
BRCA1	P38398-1.2	T1802Q	Neutral	1.202
BRCA1	P38398-1.2	T1802R	Neutral	1.202
BRCA1	P38398-1.2	T1802S	Neutral	1.287
BRCA1	P38398-1.2	T1802V	Neutral	1.244
BRCA1	P38398-1.2	T1802W	Neutral	1.159
BRCA1	P38398-1.2	T1802Y	Neutral	1.159
BRCA1	P38398-1.2	G1803A	Neutral	0.796
BRCA1	P38398-1.2	G1803C	Neutral	0.669
BRCA1	P38398-1.2	G1803D	Neutral	0.754
BRCA1	P38398-1.2	G1803E	Neutral	0.711
BRCA1	P38398-1.2	G1803F	Neutral	0.669
BRCA1	P38398-1.2	G1803H	Neutral	0.711
BRCA1	P38398-1.2	G1803I	Neutral	0.626
BRCA1	P38398-1.2	G1803K	Neutral	0.711
BRCA1	P38398-1.2	G1803L	Neutral	0.626
BRCA1	P38398-1.2	G1803M	Neutral	0.669
BRCA1	P38398-1.2	G1803N	Neutral	0.796
BRCA1	P38398-1.2	G1803P	Neutral	0.711
BRCA1	P38398-1.2	G1803Q	Neutral	0.711
BRCA1	P38398-1.2	G1803R	Neutral	0.711
BRCA1	P38398-1.2	G1803S	Neutral	0.796
BRCA1	P38398-1.2	G1803T	Neutral	0.711
BRCA1	P38398-1.2	G1803V	Neutral	0.669
BRCA1	P38398-1.2	G1803W	Neutral	0.711
BRCA1	P38398-1.2	G1803Y	Neutral	0.669
BRCA1	P38398-1.2	V1804A	Neutral	1.224
BRCA1	P38398-1.2	V1804C	Neutral	1.182
BRCA1	P38398-1.2	V1804D	Neutral	1.096
BRCA1	P38398-1.2	V1804E	Neutral	1.139
BRCA1	P38398-1.2	V1804F	Neutral	1.182
BRCA1	P38398-1.2	V1804G	Neutral	1.096
BRCA1	P38398-1.2	V1804H	Neutral	1.096
BRCA1	P38398-1.2	V1804I	Neutral	1.352
BRCA1	P38398-1.2	V1804K	Neutral	1.139
BRCA1	P38398-1.2	V1804L	Neutral	1.267
BRCA1	P38398-1.2	V1804M	Neutral	1.267
BRCA1	P38398-1.2	V1804N	Neutral	1.096
BRCA1	P38398-1.2	V1804P	Neutral	1.139
BRCA1	P38398-1.2	V1804Q	Neutral	1.139
BRCA1	P38398-1.2	V1804R	Neutral	1.096
BRCA1	P38398-1.2	V1804S	Neutral	1.139
BRCA1	P38398-1.2	V1804T	Neutral	1.224
BRCA1	P38398-1.2	V1804W	Neutral	1.096
BRCA1	P38398-1.2	V1804Y	Neutral	1.182
BRCA1	P38398-1.2	H1805A	Neutral	0.646
BRCA1	P38398-1.2	H1805C	Neutral	0.603
BRCA1	P38398-1.2	H1805D	Neutral	0.688
BRCA1	P38398-1.2	H1805E	Neutral	0.731
BRCA1	P38398-1.2	H1805F	Neutral	0.688
BRCA1	P38398-1.2	H1805G	Neutral	0.646
BRCA1	P38398-1.2	H1805I	Neutral	0.603
BRCA1	P38398-1.2	H1805K	Neutral	0.688
BRCA1	P38398-1.2	H1805L	Neutral	0.603
BRCA1	P38398-1.2	H1805M	Neutral	0.646
BRCA1	P38398-1.2	H1805N	Neutral	0.773
BRCA1	P38398-1.2	H1805P	Neutral	0.646
BRCA1	P38398-1.2	H1805Q	Neutral	0.731
BRCA1	P38398-1.2	H1805R	Neutral	0.731
BRCA1	P38398-1.2	H1805S	Neutral	0.688
BRCA1	P38398-1.2	H1805T	Neutral	0.646
BRCA1	P38398-1.2	H1805V	Neutral	0.603
BRCA1	P38398-1.2	H1805W	Neutral	0.646
BRCA1	P38398-1.2	H1805Y	Neutral	0.816
BRCA1	P38398-1.2	P1806A	Neutral	0.981
BRCA1	P38398-1.2	P1806C	Neutral	0.896
BRCA1	P38398-1.2	P1806D	Neutral	0.981
BRCA1	P38398-1.2	P1806E	Neutral	0.981
BRCA1	P38398-1.2	P1806F	Neutral	0.854
BRCA1	P38398-1.2	P1806G	Neutral	0.939
BRCA1	P38398-1.2	P1806H	Neutral	0.939
BRCA1	P38398-1.2	P1806I	Neutral	0.896
BRCA1	P38398-1.2	P1806K	Neutral	0.981
BRCA1	P38398-1.2	P1806L	Neutral	0.896
BRCA1	P38398-1.2	P1806M	Neutral	0.939
BRCA1	P38398-1.2	P1806N	Neutral	0.939
BRCA1	P38398-1.2	P1806Q	Neutral	0.981
BRCA1	P38398-1.2	P1806R	Neutral	0.939
BRCA1	P38398-1.2	P1806S	Neutral	0.981
BRCA1	P38398-1.2	P1806T	Neutral	0.981
BRCA1	P38398-1.2	P1806V	Neutral	0.939
BRCA1	P38398-1.2	P1806W	Neutral	0.854
BRCA1	P38398-1.2	P1806Y	Neutral	0.896
BRCA1	P38398-1.2	I1807A	Neutral	1.022
BRCA1	P38398-1.2	I1807C	Neutral	1.022
BRCA1	P38398-1.2	I1807D	Neutral	0.937
BRCA1	P38398-1.2	I1807E	Neutral	0.937
BRCA1	P38398-1.2	I1807F	Neutral	1.064
BRCA1	P38398-1.2	I1807G	Neutral	0.894
BRCA1	P38398-1.2	I1807H	Neutral	0.937
BRCA1	P38398-1.2	I1807K	Neutral	0.937
BRCA1	P38398-1.2	I1807L	Neutral	1.15
BRCA1	P38398-1.2	I1807M	Neutral	1.107
BRCA1	P38398-1.2	I1807N	Neutral	0.937
BRCA1	P38398-1.2	I1807P	Neutral	0.937
BRCA1	P38398-1.2	I1807Q	Neutral	0.937
BRCA1	P38398-1.2	I1807R	Neutral	0.937
BRCA1	P38398-1.2	I1807S	Neutral	0.979
BRCA1	P38398-1.2	I1807T	Neutral	1.022
BRCA1	P38398-1.2	I1807V	Neutral	1.192
BRCA1	P38398-1.2	I1807W	Neutral	0.937
BRCA1	P38398-1.2	I1807Y	Neutral	1.022
BRCA1	P38398-1.2	V1808A	Neutral	0.757
BRCA1	P38398-1.2	V1808C	Neutral	0.715
BRCA1	P38398-1.2	V1808D	Neutral	0.63
BRCA1	P38398-1.2	V1808E	Neutral	0.672
BRCA1	P38398-1.2	V1808F	Neutral	0.715
BRCA1	P38398-1.2	V1808G	Neutral	0.63
BRCA1	P38398-1.2	V1808H	Neutral	0.63
BRCA1	P38398-1.2	V1808I	Neutral	0.885
BRCA1	P38398-1.2	V1808K	Neutral	0.672
BRCA1	P38398-1.2	V1808L	Neutral	0.8
BRCA1	P38398-1.2	V1808M	Neutral	0.8
BRCA1	P38398-1.2	V1808N	Neutral	0.63
BRCA1	P38398-1.2	V1808P	Neutral	0.672
BRCA1	P38398-1.2	V1808Q	Neutral	0.672
BRCA1	P38398-1.2	V1808R	Neutral	0.63
BRCA1	P38398-1.2	V1808S	Neutral	0.672
BRCA1	P38398-1.2	V1808T	Neutral	0.757
BRCA1	P38398-1.2	V1808W	Neutral	0.63
BRCA1	P38398-1.2	V1808Y	Neutral	0.715
BRCA1	P38398-1.2	V1809A	Neutral	0.704
BRCA1	P38398-1.2	V1809C	Neutral	0.661
BRCA1	P38398-1.2	V1809D	Neutral	0.576
BRCA1	P38398-1.2	V1809E	Neutral	0.618
BRCA1	P38398-1.2	V1809F	Neutral	0.661
BRCA1	P38398-1.2	V1809G	Neutral	0.576
BRCA1	P38398-1.2	V1809H	Neutral	0.576
BRCA1	P38398-1.2	V1809I	Neutral	0.831
BRCA1	P38398-1.2	V1809K	Neutral	0.618
BRCA1	P38398-1.2	V1809L	Neutral	0.746
BRCA1	P38398-1.2	V1809M	Neutral	0.746
BRCA1	P38398-1.2	V1809N	Neutral	0.576
BRCA1	P38398-1.2	V1809P	Neutral	0.618
BRCA1	P38398-1.2	V1809Q	Neutral	0.618
BRCA1	P38398-1.2	V1809R	Neutral	0.576
BRCA1	P38398-1.2	V1809S	Neutral	0.618
BRCA1	P38398-1.2	V1809T	Neutral	0.704
BRCA1	P38398-1.2	V1809W	Neutral	0.576
BRCA1	P38398-1.2	V1809Y	Neutral	0.661
BRCA1	P38398-1.2	V1810A	Neutral	0.533
BRCA1	P38398-1.2	V1810C	Pathogenic	0.491
BRCA1	P38398-1.2	V1810D	Pathogenic	0.406
BRCA1	P38398-1.2	V1810E	Pathogenic	0.448
BRCA1	P38398-1.2	V1810F	Pathogenic	0.491
BRCA1	P38398-1.2	V1810G	Pathogenic	0.406
BRCA1	P38398-1.2	V1810H	Pathogenic	0.406
BRCA1	P38398-1.2	V1810I	Neutral	0.661
BRCA1	P38398-1.2	V1810K	Pathogenic	0.448
BRCA1	P38398-1.2	V1810L	Neutral	0.576
BRCA1	P38398-1.2	V1810M	Neutral	0.576
BRCA1	P38398-1.2	V1810N	Pathogenic	0.406
BRCA1	P38398-1.2	V1810P	Pathogenic	0.448
BRCA1	P38398-1.2	V1810Q	Pathogenic	0.448
BRCA1	P38398-1.2	V1810R	Pathogenic	0.406
BRCA1	P38398-1.2	V1810S	Pathogenic	0.448
BRCA1	P38398-1.2	V1810T	Neutral	0.533
BRCA1	P38398-1.2	V1810W	Pathogenic	0.406
BRCA1	P38398-1.2	V1810Y	Pathogenic	0.491
BRCA1	P38398-1.2	Q1811A	Neutral	0.656
BRCA1	P38398-1.2	Q1811C	Neutral	0.571
BRCA1	P38398-1.2	Q1811D	Neutral	0.698
BRCA1	P38398-1.2	Q1811E	Neutral	0.784
BRCA1	P38398-1.2	Q1811F	Neutral	0.571
BRCA1	P38398-1.2	Q1811G	Neutral	0.613
BRCA1	P38398-1.2	Q1811H	Neutral	0.698
BRCA1	P38398-1.2	Q1811I	Neutral	0.571
BRCA1	P38398-1.2	Q1811K	Neutral	0.741
BRCA1	P38398-1.2	Q1811L	Neutral	0.613
BRCA1	P38398-1.2	Q1811M	Neutral	0.698
BRCA1	P38398-1.2	Q1811N	Neutral	0.698
BRCA1	P38398-1.2	Q1811P	Neutral	0.656
BRCA1	P38398-1.2	Q1811R	Neutral	0.741
BRCA1	P38398-1.2	Q1811S	Neutral	0.698
BRCA1	P38398-1.2	Q1811T	Neutral	0.656
BRCA1	P38398-1.2	Q1811V	Neutral	0.613
BRCA1	P38398-1.2	Q1811W	Neutral	0.613
BRCA1	P38398-1.2	Q1811Y	Neutral	0.656
BRCA1	P38398-1.2	P1812A	Neutral	0.589
BRCA1	P38398-1.2	P1812C	Pathogenic	0.504
BRCA1	P38398-1.2	P1812D	Neutral	0.589
BRCA1	P38398-1.2	P1812E	Neutral	0.589
BRCA1	P38398-1.2	P1812F	Pathogenic	0.462
BRCA1	P38398-1.2	P1812G	Neutral	0.547
BRCA1	P38398-1.2	P1812H	Neutral	0.547
BRCA1	P38398-1.2	P1812I	Pathogenic	0.504
BRCA1	P38398-1.2	P1812K	Neutral	0.589
BRCA1	P38398-1.2	P1812L	Pathogenic	0.504
BRCA1	P38398-1.2	P1812M	Neutral	0.547
BRCA1	P38398-1.2	P1812N	Neutral	0.547
BRCA1	P38398-1.2	P1812Q	Neutral	0.589
BRCA1	P38398-1.2	P1812R	Neutral	0.547
BRCA1	P38398-1.2	P1812S	Neutral	0.589
BRCA1	P38398-1.2	P1812T	Neutral	0.589
BRCA1	P38398-1.2	P1812V	Neutral	0.547
BRCA1	P38398-1.2	P1812W	Pathogenic	0.462
BRCA1	P38398-1.2	P1812Y	Pathogenic	0.504
BRCA1	P38398-1.2	D1813A	Neutral	0.799
BRCA1	P38398-1.2	D1813C	Neutral	0.756
BRCA1	P38398-1.2	D1813E	Neutral	0.969
BRCA1	P38398-1.2	D1813F	Neutral	0.756
BRCA1	P38398-1.2	D1813G	Neutral	0.841
BRCA1	P38398-1.2	D1813H	Neutral	0.841
BRCA1	P38398-1.2	D1813I	Neutral	0.756
BRCA1	P38398-1.2	D1813K	Neutral	0.841
BRCA1	P38398-1.2	D1813L	Neutral	0.714
BRCA1	P38398-1.2	D1813M	Neutral	0.756
BRCA1	P38398-1.2	D1813N	Neutral	0.926
BRCA1	P38398-1.2	D1813P	Neutral	0.841
BRCA1	P38398-1.2	D1813Q	Neutral	0.884
BRCA1	P38398-1.2	D1813R	Neutral	0.799
BRCA1	P38398-1.2	D1813S	Neutral	0.884
BRCA1	P38398-1.2	D1813T	Neutral	0.841
BRCA1	P38398-1.2	D1813V	Neutral	0.756
BRCA1	P38398-1.2	D1813W	Neutral	0.714
BRCA1	P38398-1.2	D1813Y	Neutral	0.756
BRCA1	P38398-1.2	A1814C	Neutral	0.79
BRCA1	P38398-1.2	A1814D	Neutral	0.704
BRCA1	P38398-1.2	A1814E	Neutral	0.747
BRCA1	P38398-1.2	A1814F	Neutral	0.704
BRCA1	P38398-1.2	A1814G	Neutral	0.79
BRCA1	P38398-1.2	A1814H	Neutral	0.704
BRCA1	P38398-1.2	A1814I	Neutral	0.747
BRCA1	P38398-1.2	A1814K	Neutral	0.747
BRCA1	P38398-1.2	A1814L	Neutral	0.747
BRCA1	P38398-1.2	A1814M	Neutral	0.747
BRCA1	P38398-1.2	A1814N	Neutral	0.704
BRCA1	P38398-1.2	A1814P	Neutral	0.747
BRCA1	P38398-1.2	A1814Q	Neutral	0.747
BRCA1	P38398-1.2	A1814R	Neutral	0.747
BRCA1	P38398-1.2	A1814S	Neutral	0.832
BRCA1	P38398-1.2	A1814T	Neutral	0.79
BRCA1	P38398-1.2	A1814V	Neutral	0.79
BRCA1	P38398-1.2	A1814W	Neutral	0.662
BRCA1	P38398-1.2	A1814Y	Neutral	0.704
BRCA1	P38398-1.2	W1815A	Pathogenic	0.131
BRCA1	P38398-1.2	W1815C	Pathogenic	0.173
BRCA1	P38398-1.2	W1815D	Pathogenic	0.088
BRCA1	P38398-1.2	W1815E	Pathogenic	0.131
BRCA1	P38398-1.2	W1815F	Pathogenic	0.301
BRCA1	P38398-1.2	W1815G	Pathogenic	0.173
BRCA1	P38398-1.2	W1815H	Pathogenic	0.173
BRCA1	P38398-1.2	W1815I	Pathogenic	0.131
BRCA1	P38398-1.2	W1815K	Pathogenic	0.131
BRCA1	P38398-1.2	W1815L	Pathogenic	0.173
BRCA1	P38398-1.2	W1815M	Pathogenic	0.216
BRCA1	P38398-1.2	W1815N	Pathogenic	0.088
BRCA1	P38398-1.2	W1815P	Pathogenic	0.088
BRCA1	P38398-1.2	W1815Q	Pathogenic	0.173
BRCA1	P38398-1.2	W1815R	Pathogenic	0.131
BRCA1	P38398-1.2	W1815S	Pathogenic	0.131
BRCA1	P38398-1.2	W1815T	Pathogenic	0.173
BRCA1	P38398-1.2	W1815V	Pathogenic	0.131
BRCA1	P38398-1.2	W1815Y	Pathogenic	0.344
BRCA1	P38398-1.2	T1816A	Neutral	0.871
BRCA1	P38398-1.2	T1816C	Neutral	0.828
BRCA1	P38398-1.2	T1816D	Neutral	0.828
BRCA1	P38398-1.2	T1816E	Neutral	0.828
BRCA1	P38398-1.2	T1816F	Neutral	0.786
BRCA1	P38398-1.2	T1816G	Neutral	0.786
BRCA1	P38398-1.2	T1816H	Neutral	0.786
BRCA1	P38398-1.2	T1816I	Neutral	0.828
BRCA1	P38398-1.2	T1816K	Neutral	0.828
BRCA1	P38398-1.2	T1816L	Neutral	0.828
BRCA1	P38398-1.2	T1816M	Neutral	0.828
BRCA1	P38398-1.2	T1816N	Neutral	0.871
BRCA1	P38398-1.2	T1816P	Neutral	0.828
BRCA1	P38398-1.2	T1816Q	Neutral	0.828
BRCA1	P38398-1.2	T1816R	Neutral	0.828
BRCA1	P38398-1.2	T1816S	Neutral	0.914
BRCA1	P38398-1.2	T1816V	Neutral	0.871
BRCA1	P38398-1.2	T1816W	Neutral	0.786
BRCA1	P38398-1.2	T1816Y	Neutral	0.786
BRCA1	P38398-1.2	E1817A	Neutral	1.02
BRCA1	P38398-1.2	E1817C	Neutral	0.893
BRCA1	P38398-1.2	E1817D	Neutral	1.148
BRCA1	P38398-1.2	E1817F	Neutral	0.935
BRCA1	P38398-1.2	E1817G	Neutral	0.978
BRCA1	P38398-1.2	E1817H	Neutral	1.063
BRCA1	P38398-1.2	E1817I	Neutral	0.935
BRCA1	P38398-1.2	E1817K	Neutral	1.105
BRCA1	P38398-1.2	E1817L	Neutral	0.935
BRCA1	P38398-1.2	E1817M	Neutral	0.978
BRCA1	P38398-1.2	E1817N	Neutral	1.063
BRCA1	P38398-1.2	E1817P	Neutral	1.02
BRCA1	P38398-1.2	E1817Q	Neutral	1.148
BRCA1	P38398-1.2	E1817R	Neutral	1.063
BRCA1	P38398-1.2	E1817S	Neutral	1.063
BRCA1	P38398-1.2	E1817T	Neutral	1.02
BRCA1	P38398-1.2	E1817V	Neutral	0.978
BRCA1	P38398-1.2	E1817W	Neutral	0.935
BRCA1	P38398-1.2	E1817Y	Neutral	0.978
BRCA1	P38398-1.2	D1818A	Neutral	0.764
BRCA1	P38398-1.2	D1818C	Neutral	0.722
BRCA1	P38398-1.2	D1818E	Neutral	0.935
BRCA1	P38398-1.2	D1818F	Neutral	0.722
BRCA1	P38398-1.2	D1818G	Neutral	0.807
BRCA1	P38398-1.2	D1818H	Neutral	0.807
BRCA1	P38398-1.2	D1818I	Neutral	0.722
BRCA1	P38398-1.2	D1818K	Neutral	0.807
BRCA1	P38398-1.2	D1818L	Neutral	0.679
BRCA1	P38398-1.2	D1818M	Neutral	0.722
BRCA1	P38398-1.2	D1818N	Neutral	0.892
BRCA1	P38398-1.2	D1818P	Neutral	0.807
BRCA1	P38398-1.2	D1818Q	Neutral	0.849
BRCA1	P38398-1.2	D1818R	Neutral	0.764
BRCA1	P38398-1.2	D1818S	Neutral	0.849
BRCA1	P38398-1.2	D1818T	Neutral	0.807
BRCA1	P38398-1.2	D1818V	Neutral	0.722
BRCA1	P38398-1.2	D1818W	Neutral	0.679
BRCA1	P38398-1.2	D1818Y	Neutral	0.722
BRCA1	P38398-1.2	N1819A	Neutral	1.09
BRCA1	P38398-1.2	N1819C	Neutral	1.047
BRCA1	P38398-1.2	N1819D	Neutral	1.217
BRCA1	P38398-1.2	N1819E	Neutral	1.175
BRCA1	P38398-1.2	N1819F	Neutral	1.047
BRCA1	P38398-1.2	N1819G	Neutral	1.175
BRCA1	P38398-1.2	N1819H	Neutral	1.217
BRCA1	P38398-1.2	N1819I	Neutral	1.047
BRCA1	P38398-1.2	N1819K	Neutral	1.175
BRCA1	P38398-1.2	N1819L	Neutral	1.047
BRCA1	P38398-1.2	N1819M	Neutral	1.09
BRCA1	P38398-1.2	N1819P	Neutral	1.09
BRCA1	P38398-1.2	N1819Q	Neutral	1.175
BRCA1	P38398-1.2	N1819R	Neutral	1.175
BRCA1	P38398-1.2	N1819S	Neutral	1.217
BRCA1	P38398-1.2	N1819T	Neutral	1.175
BRCA1	P38398-1.2	N1819V	Neutral	1.047
BRCA1	P38398-1.2	N1819W	Neutral	1.004
BRCA1	P38398-1.2	N1819Y	Neutral	1.09
BRCA1	P38398-1.2	G1820A	Neutral	1.076
BRCA1	P38398-1.2	G1820C	Neutral	0.948
BRCA1	P38398-1.2	G1820D	Neutral	1.033
BRCA1	P38398-1.2	G1820E	Neutral	0.991
BRCA1	P38398-1.2	G1820F	Neutral	0.948
BRCA1	P38398-1.2	G1820H	Neutral	0.991
BRCA1	P38398-1.2	G1820I	Neutral	0.905
BRCA1	P38398-1.2	G1820K	Neutral	0.991
BRCA1	P38398-1.2	G1820L	Neutral	0.905
BRCA1	P38398-1.2	G1820M	Neutral	0.948
BRCA1	P38398-1.2	G1820N	Neutral	1.076
BRCA1	P38398-1.2	G1820P	Neutral	0.991
BRCA1	P38398-1.2	G1820Q	Neutral	0.991
BRCA1	P38398-1.2	G1820R	Neutral	0.991
BRCA1	P38398-1.2	G1820S	Neutral	1.076
BRCA1	P38398-1.2	G1820T	Neutral	0.991
BRCA1	P38398-1.2	G1820V	Neutral	0.948
BRCA1	P38398-1.2	G1820W	Neutral	0.991
BRCA1	P38398-1.2	G1820Y	Neutral	0.948
BRCA1	P38398-1.2	F1821A	Neutral	0.678
BRCA1	P38398-1.2	F1821C	Neutral	0.678
BRCA1	P38398-1.2	F1821D	Neutral	0.635
BRCA1	P38398-1.2	F1821E	Neutral	0.635
BRCA1	P38398-1.2	F1821G	Neutral	0.635
BRCA1	P38398-1.2	F1821H	Neutral	0.721
BRCA1	P38398-1.2	F1821I	Neutral	0.763
BRCA1	P38398-1.2	F1821K	Neutral	0.635
BRCA1	P38398-1.2	F1821L	Neutral	0.763
BRCA1	P38398-1.2	F1821M	Neutral	0.763
BRCA1	P38398-1.2	F1821N	Neutral	0.635
BRCA1	P38398-1.2	F1821P	Neutral	0.593
BRCA1	P38398-1.2	F1821Q	Neutral	0.635
BRCA1	P38398-1.2	F1821R	Neutral	0.635
BRCA1	P38398-1.2	F1821S	Neutral	0.678
BRCA1	P38398-1.2	F1821T	Neutral	0.678
BRCA1	P38398-1.2	F1821V	Neutral	0.721
BRCA1	P38398-1.2	F1821W	Neutral	0.806
BRCA1	P38398-1.2	F1821Y	Neutral	0.891
BRCA1	P38398-1.2	H1822A	Neutral	0.823
BRCA1	P38398-1.2	H1822C	Neutral	0.78
BRCA1	P38398-1.2	H1822D	Neutral	0.866
BRCA1	P38398-1.2	H1822E	Neutral	0.908
BRCA1	P38398-1.2	H1822F	Neutral	0.866
BRCA1	P38398-1.2	H1822G	Neutral	0.823
BRCA1	P38398-1.2	H1822I	Neutral	0.78
BRCA1	P38398-1.2	H1822K	Neutral	0.866
BRCA1	P38398-1.2	H1822L	Neutral	0.78
BRCA1	P38398-1.2	H1822M	Neutral	0.823
BRCA1	P38398-1.2	H1822N	Neutral	0.951
BRCA1	P38398-1.2	H1822P	Neutral	0.823
BRCA1	P38398-1.2	H1822Q	Neutral	0.908
BRCA1	P38398-1.2	H1822R	Neutral	0.908
BRCA1	P38398-1.2	H1822S	Neutral	0.866
BRCA1	P38398-1.2	H1822T	Neutral	0.823
BRCA1	P38398-1.2	H1822V	Neutral	0.78
BRCA1	P38398-1.2	H1822W	Neutral	0.823
BRCA1	P38398-1.2	H1822Y	Neutral	0.993
BRCA1	P38398-1.2	A1823C	Neutral	1.106
BRCA1	P38398-1.2	A1823D	Neutral	1.021
BRCA1	P38398-1.2	A1823E	Neutral	1.064
BRCA1	P38398-1.2	A1823F	Neutral	1.021
BRCA1	P38398-1.2	A1823G	Neutral	1.106
BRCA1	P38398-1.2	A1823H	Neutral	1.021
BRCA1	P38398-1.2	A1823I	Neutral	1.064
BRCA1	P38398-1.2	A1823K	Neutral	1.064
BRCA1	P38398-1.2	A1823L	Neutral	1.064
BRCA1	P38398-1.2	A1823M	Neutral	1.064
BRCA1	P38398-1.2	A1823N	Neutral	1.021
BRCA1	P38398-1.2	A1823P	Neutral	1.064
BRCA1	P38398-1.2	A1823Q	Neutral	1.064
BRCA1	P38398-1.2	A1823R	Neutral	1.064
BRCA1	P38398-1.2	A1823S	Neutral	1.149
BRCA1	P38398-1.2	A1823T	Neutral	1.106
BRCA1	P38398-1.2	A1823V	Neutral	1.106
BRCA1	P38398-1.2	A1823W	Neutral	0.978
BRCA1	P38398-1.2	A1823Y	Neutral	1.021
BRCA1	P38398-1.2	I1824A	Neutral	0.68
BRCA1	P38398-1.2	I1824C	Neutral	0.68
BRCA1	P38398-1.2	I1824D	Neutral	0.595
BRCA1	P38398-1.2	I1824E	Neutral	0.595
BRCA1	P38398-1.2	I1824F	Neutral	0.723
BRCA1	P38398-1.2	I1824G	Neutral	0.553
BRCA1	P38398-1.2	I1824H	Neutral	0.595
BRCA1	P38398-1.2	I1824K	Neutral	0.595
BRCA1	P38398-1.2	I1824L	Neutral	0.808
BRCA1	P38398-1.2	I1824M	Neutral	0.765
BRCA1	P38398-1.2	I1824N	Neutral	0.595
BRCA1	P38398-1.2	I1824P	Neutral	0.595
BRCA1	P38398-1.2	I1824Q	Neutral	0.595
BRCA1	P38398-1.2	I1824R	Neutral	0.595
BRCA1	P38398-1.2	I1824S	Neutral	0.638
BRCA1	P38398-1.2	I1824T	Neutral	0.68
BRCA1	P38398-1.2	I1824V	Neutral	0.851
BRCA1	P38398-1.2	I1824W	Neutral	0.595
BRCA1	P38398-1.2	I1824Y	Neutral	0.68
BRCA1	P38398-1.2	G1825A	Neutral	0.928
BRCA1	P38398-1.2	G1825C	Neutral	0.8
BRCA1	P38398-1.2	G1825D	Neutral	0.885
BRCA1	P38398-1.2	G1825E	Neutral	0.842
BRCA1	P38398-1.2	G1825F	Neutral	0.8
BRCA1	P38398-1.2	G1825H	Neutral	0.842
BRCA1	P38398-1.2	G1825I	Neutral	0.757
BRCA1	P38398-1.2	G1825K	Neutral	0.842
BRCA1	P38398-1.2	G1825L	Neutral	0.757
BRCA1	P38398-1.2	G1825M	Neutral	0.8
BRCA1	P38398-1.2	G1825N	Neutral	0.928
BRCA1	P38398-1.2	G1825P	Neutral	0.842
BRCA1	P38398-1.2	G1825Q	Neutral	0.842
BRCA1	P38398-1.2	G1825R	Neutral	0.842
BRCA1	P38398-1.2	G1825S	Neutral	0.928
BRCA1	P38398-1.2	G1825T	Neutral	0.842
BRCA1	P38398-1.2	G1825V	Neutral	0.8
BRCA1	P38398-1.2	G1825W	Neutral	0.842
BRCA1	P38398-1.2	G1825Y	Neutral	0.8
BRCA1	P38398-1.2	Q1826A	Neutral	0.997
BRCA1	P38398-1.2	Q1826C	Neutral	0.912
BRCA1	P38398-1.2	Q1826D	Neutral	1.04
BRCA1	P38398-1.2	Q1826E	Neutral	1.125
BRCA1	P38398-1.2	Q1826F	Neutral	0.912
BRCA1	P38398-1.2	Q1826G	Neutral	0.955
BRCA1	P38398-1.2	Q1826H	Neutral	1.04
BRCA1	P38398-1.2	Q1826I	Neutral	0.912
BRCA1	P38398-1.2	Q1826K	Neutral	1.083
BRCA1	P38398-1.2	Q1826L	Neutral	0.955
BRCA1	P38398-1.2	Q1826M	Neutral	1.04
BRCA1	P38398-1.2	Q1826N	Neutral	1.04
BRCA1	P38398-1.2	Q1826P	Neutral	0.997
BRCA1	P38398-1.2	Q1826R	Neutral	1.083
BRCA1	P38398-1.2	Q1826S	Neutral	1.04
BRCA1	P38398-1.2	Q1826T	Neutral	0.997
BRCA1	P38398-1.2	Q1826V	Neutral	0.955
BRCA1	P38398-1.2	Q1826W	Neutral	0.955
BRCA1	P38398-1.2	Q1826Y	Neutral	0.997
BRCA1	P38398-1.2	M1827A	Neutral	0.69
BRCA1	P38398-1.2	M1827C	Neutral	0.69
BRCA1	P38398-1.2	M1827D	Neutral	0.605
BRCA1	P38398-1.2	M1827E	Neutral	0.648
BRCA1	P38398-1.2	M1827F	Neutral	0.733
BRCA1	P38398-1.2	M1827G	Neutral	0.605
BRCA1	P38398-1.2	M1827H	Neutral	0.648
BRCA1	P38398-1.2	M1827I	Neutral	0.776
BRCA1	P38398-1.2	M1827K	Neutral	0.69
BRCA1	P38398-1.2	M1827L	Neutral	0.818
BRCA1	P38398-1.2	M1827N	Neutral	0.648
BRCA1	P38398-1.2	M1827P	Neutral	0.648
BRCA1	P38398-1.2	M1827Q	Neutral	0.733
BRCA1	P38398-1.2	M1827R	Neutral	0.69
BRCA1	P38398-1.2	M1827S	Neutral	0.69
BRCA1	P38398-1.2	M1827T	Neutral	0.69
BRCA1	P38398-1.2	M1827V	Neutral	0.776
BRCA1	P38398-1.2	M1827W	Neutral	0.69
BRCA1	P38398-1.2	M1827Y	Neutral	0.69
BRCA1	P38398-1.2	C1828A	Neutral	0.787
BRCA1	P38398-1.2	C1828D	Neutral	0.659
BRCA1	P38398-1.2	C1828E	Neutral	0.616
BRCA1	P38398-1.2	C1828F	Neutral	0.702
BRCA1	P38398-1.2	C1828G	Neutral	0.659
BRCA1	P38398-1.2	C1828H	Neutral	0.659
BRCA1	P38398-1.2	C1828I	Neutral	0.744
BRCA1	P38398-1.2	C1828K	Neutral	0.659
BRCA1	P38398-1.2	C1828L	Neutral	0.744
BRCA1	P38398-1.2	C1828M	Neutral	0.744
BRCA1	P38398-1.2	C1828N	Neutral	0.659
BRCA1	P38398-1.2	C1828P	Neutral	0.659
BRCA1	P38398-1.2	C1828Q	Neutral	0.659
BRCA1	P38398-1.2	C1828R	Neutral	0.659
BRCA1	P38398-1.2	C1828S	Neutral	0.744
BRCA1	P38398-1.2	C1828T	Neutral	0.744
BRCA1	P38398-1.2	C1828V	Neutral	0.744
BRCA1	P38398-1.2	C1828W	Neutral	0.702
BRCA1	P38398-1.2	C1828Y	Neutral	0.702
BRCA1	P38398-1.2	E1829A	Neutral	1.129
BRCA1	P38398-1.2	E1829C	Neutral	1.001
BRCA1	P38398-1.2	E1829D	Neutral	1.257
BRCA1	P38398-1.2	E1829F	Neutral	1.044
BRCA1	P38398-1.2	E1829G	Neutral	1.086
BRCA1	P38398-1.2	E1829H	Neutral	1.172
BRCA1	P38398-1.2	E1829I	Neutral	1.044
BRCA1	P38398-1.2	E1829K	Neutral	1.214
BRCA1	P38398-1.2	E1829L	Neutral	1.044
BRCA1	P38398-1.2	E1829M	Neutral	1.086
BRCA1	P38398-1.2	E1829N	Neutral	1.172
BRCA1	P38398-1.2	E1829P	Neutral	1.129
BRCA1	P38398-1.2	E1829Q	Neutral	1.257
BRCA1	P38398-1.2	E1829R	Neutral	1.172
BRCA1	P38398-1.2	E1829S	Neutral	1.172
BRCA1	P38398-1.2	E1829T	Neutral	1.129
BRCA1	P38398-1.2	E1829V	Neutral	1.086
BRCA1	P38398-1.2	E1829W	Neutral	1.044
BRCA1	P38398-1.2	E1829Y	Neutral	1.086
BRCA1	P38398-1.2	A1830C	Neutral	0.723
BRCA1	P38398-1.2	A1830D	Neutral	0.638
BRCA1	P38398-1.2	A1830E	Neutral	0.68
BRCA1	P38398-1.2	A1830F	Neutral	0.638
BRCA1	P38398-1.2	A1830G	Neutral	0.723
BRCA1	P38398-1.2	A1830H	Neutral	0.638
BRCA1	P38398-1.2	A1830I	Neutral	0.68
BRCA1	P38398-1.2	A1830K	Neutral	0.68
BRCA1	P38398-1.2	A1830L	Neutral	0.68
BRCA1	P38398-1.2	A1830M	Neutral	0.68
BRCA1	P38398-1.2	A1830N	Neutral	0.638
BRCA1	P38398-1.2	A1830P	Neutral	0.68
BRCA1	P38398-1.2	A1830Q	Neutral	0.68
BRCA1	P38398-1.2	A1830R	Neutral	0.68
BRCA1	P38398-1.2	A1830S	Neutral	0.765
BRCA1	P38398-1.2	A1830T	Neutral	0.723
BRCA1	P38398-1.2	A1830V	Neutral	0.723
BRCA1	P38398-1.2	A1830W	Neutral	0.595
BRCA1	P38398-1.2	A1830Y	Neutral	0.638
BRCA1	P38398-1.2	P1831A	Neutral	0.894
BRCA1	P38398-1.2	P1831C	Neutral	0.808
BRCA1	P38398-1.2	P1831D	Neutral	0.894
BRCA1	P38398-1.2	P1831E	Neutral	0.894
BRCA1	P38398-1.2	P1831F	Neutral	0.766
BRCA1	P38398-1.2	P1831G	Neutral	0.851
BRCA1	P38398-1.2	P1831H	Neutral	0.851
BRCA1	P38398-1.2	P1831I	Neutral	0.808
BRCA1	P38398-1.2	P1831K	Neutral	0.894
BRCA1	P38398-1.2	P1831L	Neutral	0.808
BRCA1	P38398-1.2	P1831M	Neutral	0.851
BRCA1	P38398-1.2	P1831N	Neutral	0.851
BRCA1	P38398-1.2	P1831Q	Neutral	0.894
BRCA1	P38398-1.2	P1831R	Neutral	0.851
BRCA1	P38398-1.2	P1831S	Neutral	0.894
BRCA1	P38398-1.2	P1831T	Neutral	0.894
BRCA1	P38398-1.2	P1831V	Neutral	0.851
BRCA1	P38398-1.2	P1831W	Neutral	0.766
BRCA1	P38398-1.2	P1831Y	Neutral	0.808
BRCA1	P38398-1.2	V1832A	Neutral	0.622
BRCA1	P38398-1.2	V1832C	Neutral	0.58
BRCA1	P38398-1.2	V1832D	Pathogenic	0.495
BRCA1	P38398-1.2	V1832E	Neutral	0.537
BRCA1	P38398-1.2	V1832F	Neutral	0.58
BRCA1	P38398-1.2	V1832G	Pathogenic	0.495
BRCA1	P38398-1.2	V1832H	Pathogenic	0.495
BRCA1	P38398-1.2	V1832I	Neutral	0.75
BRCA1	P38398-1.2	V1832K	Neutral	0.537
BRCA1	P38398-1.2	V1832L	Neutral	0.665
BRCA1	P38398-1.2	V1832M	Neutral	0.665
BRCA1	P38398-1.2	V1832N	Pathogenic	0.495
BRCA1	P38398-1.2	V1832P	Neutral	0.537
BRCA1	P38398-1.2	V1832Q	Neutral	0.537
BRCA1	P38398-1.2	V1832R	Pathogenic	0.495
BRCA1	P38398-1.2	V1832S	Neutral	0.537
BRCA1	P38398-1.2	V1832T	Neutral	0.622
BRCA1	P38398-1.2	V1832W	Pathogenic	0.495
BRCA1	P38398-1.2	V1832Y	Neutral	0.58
BRCA1	P38398-1.2	V1833A	Neutral	0.708
BRCA1	P38398-1.2	V1833C	Neutral	0.665
BRCA1	P38398-1.2	V1833D	Neutral	0.58
BRCA1	P38398-1.2	V1833E	Neutral	0.623
BRCA1	P38398-1.2	V1833F	Neutral	0.665
BRCA1	P38398-1.2	V1833G	Neutral	0.58
BRCA1	P38398-1.2	V1833H	Neutral	0.58
BRCA1	P38398-1.2	V1833I	Neutral	0.836
BRCA1	P38398-1.2	V1833K	Neutral	0.623
BRCA1	P38398-1.2	V1833L	Neutral	0.751
BRCA1	P38398-1.2	V1833M	Neutral	0.751
BRCA1	P38398-1.2	V1833N	Neutral	0.58
BRCA1	P38398-1.2	V1833P	Neutral	0.623
BRCA1	P38398-1.2	V1833Q	Neutral	0.623
BRCA1	P38398-1.2	V1833R	Neutral	0.58
BRCA1	P38398-1.2	V1833S	Neutral	0.623
BRCA1	P38398-1.2	V1833T	Neutral	0.708
BRCA1	P38398-1.2	V1833W	Neutral	0.58
BRCA1	P38398-1.2	V1833Y	Neutral	0.665
BRCA1	P38398-1.2	T1834A	Neutral	0.81
BRCA1	P38398-1.2	T1834C	Neutral	0.768
BRCA1	P38398-1.2	T1834D	Neutral	0.768
BRCA1	P38398-1.2	T1834E	Neutral	0.768
BRCA1	P38398-1.2	T1834F	Neutral	0.725
BRCA1	P38398-1.2	T1834G	Neutral	0.725
BRCA1	P38398-1.2	T1834H	Neutral	0.725
BRCA1	P38398-1.2	T1834I	Neutral	0.768
BRCA1	P38398-1.2	T1834K	Neutral	0.768
BRCA1	P38398-1.2	T1834L	Neutral	0.768
BRCA1	P38398-1.2	T1834M	Neutral	0.768
BRCA1	P38398-1.2	T1834N	Neutral	0.81
BRCA1	P38398-1.2	T1834P	Neutral	0.768
BRCA1	P38398-1.2	T1834Q	Neutral	0.768
BRCA1	P38398-1.2	T1834R	Neutral	0.768
BRCA1	P38398-1.2	T1834S	Neutral	0.853
BRCA1	P38398-1.2	T1834V	Neutral	0.81
BRCA1	P38398-1.2	T1834W	Neutral	0.725
BRCA1	P38398-1.2	T1834Y	Neutral	0.725
BRCA1	P38398-1.2	R1835A	Pathogenic	0.527
BRCA1	P38398-1.2	R1835C	Pathogenic	0.441
BRCA1	P38398-1.2	R1835D	Pathogenic	0.484
BRCA1	P38398-1.2	R1835E	Neutral	0.569
BRCA1	P38398-1.2	R1835F	Pathogenic	0.441
BRCA1	P38398-1.2	R1835G	Pathogenic	0.484
BRCA1	P38398-1.2	R1835H	Neutral	0.569
BRCA1	P38398-1.2	R1835I	Pathogenic	0.441
BRCA1	P38398-1.2	R1835K	Neutral	0.654
BRCA1	P38398-1.2	R1835L	Pathogenic	0.484
BRCA1	P38398-1.2	R1835M	Pathogenic	0.527
BRCA1	P38398-1.2	R1835N	Neutral	0.569
BRCA1	P38398-1.2	R1835P	Pathogenic	0.484
BRCA1	P38398-1.2	R1835Q	Neutral	0.612
BRCA1	P38398-1.2	R1835S	Pathogenic	0.527
BRCA1	P38398-1.2	R1835T	Pathogenic	0.527
BRCA1	P38398-1.2	R1835V	Pathogenic	0.441
BRCA1	P38398-1.2	R1835W	Pathogenic	0.441
BRCA1	P38398-1.2	R1835Y	Pathogenic	0.484
BRCA1	P38398-1.2	E1836A	Neutral	0.854
BRCA1	P38398-1.2	E1836C	Neutral	0.727
BRCA1	P38398-1.2	E1836D	Neutral	0.982
BRCA1	P38398-1.2	E1836F	Neutral	0.769
BRCA1	P38398-1.2	E1836G	Neutral	0.812
BRCA1	P38398-1.2	E1836H	Neutral	0.897
BRCA1	P38398-1.2	E1836I	Neutral	0.769
BRCA1	P38398-1.2	E1836K	Neutral	0.94
BRCA1	P38398-1.2	E1836L	Neutral	0.769
BRCA1	P38398-1.2	E1836M	Neutral	0.812
BRCA1	P38398-1.2	E1836N	Neutral	0.897
BRCA1	P38398-1.2	E1836P	Neutral	0.854
BRCA1	P38398-1.2	E1836Q	Neutral	0.982
BRCA1	P38398-1.2	E1836R	Neutral	0.897
BRCA1	P38398-1.2	E1836S	Neutral	0.897
BRCA1	P38398-1.2	E1836T	Neutral	0.854
BRCA1	P38398-1.2	E1836V	Neutral	0.812
BRCA1	P38398-1.2	E1836W	Neutral	0.769
BRCA1	P38398-1.2	E1836Y	Neutral	0.812
BRCA1	P38398-1.2	W1837A	Pathogenic	0.0
BRCA1	P38398-1.2	W1837C	Pathogenic	0.0
BRCA1	P38398-1.2	W1837D	Pathogenic	0.0
BRCA1	P38398-1.2	W1837E	Pathogenic	0.0
BRCA1	P38398-1.2	W1837F	Pathogenic	0.0
BRCA1	P38398-1.2	W1837G	Pathogenic	0.0
BRCA1	P38398-1.2	W1837H	Pathogenic	0.0
BRCA1	P38398-1.2	W1837I	Pathogenic	0.0
BRCA1	P38398-1.2	W1837K	Pathogenic	0.0
BRCA1	P38398-1.2	W1837L	Pathogenic	0.0
BRCA1	P38398-1.2	W1837M	Pathogenic	0.0
BRCA1	P38398-1.2	W1837N	Pathogenic	0.0
BRCA1	P38398-1.2	W1837P	Pathogenic	0.0
BRCA1	P38398-1.2	W1837Q	Pathogenic	0.0
BRCA1	P38398-1.2	W1837R	Pathogenic	0.0
BRCA1	P38398-1.2	W1837S	Pathogenic	0.0
BRCA1	P38398-1.2	W1837T	Pathogenic	0.0
BRCA1	P38398-1.2	W1837V	Pathogenic	0.0
BRCA1	P38398-1.2	W1837Y	Pathogenic	0.0
BRCA1	P38398-1.2	V1838A	Neutral	0.723
BRCA1	P38398-1.2	V1838C	Neutral	0.681
BRCA1	P38398-1.2	V1838D	Neutral	0.596
BRCA1	P38398-1.2	V1838E	Neutral	0.638
BRCA1	P38398-1.2	V1838F	Neutral	0.681
BRCA1	P38398-1.2	V1838G	Neutral	0.596
BRCA1	P38398-1.2	V1838H	Neutral	0.596
BRCA1	P38398-1.2	V1838I	Neutral	0.851
BRCA1	P38398-1.2	V1838K	Neutral	0.638
BRCA1	P38398-1.2	V1838L	Neutral	0.766
BRCA1	P38398-1.2	V1838M	Neutral	0.766
BRCA1	P38398-1.2	V1838N	Neutral	0.596
BRCA1	P38398-1.2	V1838P	Neutral	0.638
BRCA1	P38398-1.2	V1838Q	Neutral	0.638
BRCA1	P38398-1.2	V1838R	Neutral	0.596
BRCA1	P38398-1.2	V1838S	Neutral	0.638
BRCA1	P38398-1.2	V1838T	Neutral	0.723
BRCA1	P38398-1.2	V1838W	Neutral	0.596
BRCA1	P38398-1.2	V1838Y	Neutral	0.681
BRCA1	P38398-1.2	L1839A	Neutral	0.695
BRCA1	P38398-1.2	L1839C	Neutral	0.695
BRCA1	P38398-1.2	L1839D	Neutral	0.568
BRCA1	P38398-1.2	L1839E	Neutral	0.61
BRCA1	P38398-1.2	L1839F	Neutral	0.738
BRCA1	P38398-1.2	L1839G	Neutral	0.568
BRCA1	P38398-1.2	L1839H	Neutral	0.61
BRCA1	P38398-1.2	L1839I	Neutral	0.823
BRCA1	P38398-1.2	L1839K	Neutral	0.653
BRCA1	P38398-1.2	L1839M	Neutral	0.823
BRCA1	P38398-1.2	L1839N	Neutral	0.61
BRCA1	P38398-1.2	L1839P	Neutral	0.61
BRCA1	P38398-1.2	L1839Q	Neutral	0.653
BRCA1	P38398-1.2	L1839R	Neutral	0.653
BRCA1	P38398-1.2	L1839S	Neutral	0.653
BRCA1	P38398-1.2	L1839T	Neutral	0.695
BRCA1	P38398-1.2	L1839V	Neutral	0.78
BRCA1	P38398-1.2	L1839W	Neutral	0.653
BRCA1	P38398-1.2	L1839Y	Neutral	0.695
BRCA1	P38398-1.2	D1840A	Pathogenic	0.428
BRCA1	P38398-1.2	D1840C	Pathogenic	0.385
BRCA1	P38398-1.2	D1840E	Neutral	0.598
BRCA1	P38398-1.2	D1840F	Pathogenic	0.385
BRCA1	P38398-1.2	D1840G	Pathogenic	0.47
BRCA1	P38398-1.2	D1840H	Pathogenic	0.47
BRCA1	P38398-1.2	D1840I	Pathogenic	0.385
BRCA1	P38398-1.2	D1840K	Pathogenic	0.47
BRCA1	P38398-1.2	D1840L	Pathogenic	0.342
BRCA1	P38398-1.2	D1840M	Pathogenic	0.385
BRCA1	P38398-1.2	D1840N	Neutral	0.555
BRCA1	P38398-1.2	D1840P	Pathogenic	0.47
BRCA1	P38398-1.2	D1840Q	Pathogenic	0.513
BRCA1	P38398-1.2	D1840R	Pathogenic	0.428
BRCA1	P38398-1.2	D1840S	Pathogenic	0.513
BRCA1	P38398-1.2	D1840T	Pathogenic	0.47
BRCA1	P38398-1.2	D1840V	Pathogenic	0.385
BRCA1	P38398-1.2	D1840W	Pathogenic	0.342
BRCA1	P38398-1.2	D1840Y	Pathogenic	0.385
BRCA1	P38398-1.2	S1841A	Neutral	0.786
BRCA1	P38398-1.2	S1841C	Neutral	0.701
BRCA1	P38398-1.2	S1841D	Neutral	0.743
BRCA1	P38398-1.2	S1841E	Neutral	0.743
BRCA1	P38398-1.2	S1841F	Neutral	0.658
BRCA1	P38398-1.2	S1841G	Neutral	0.743
BRCA1	P38398-1.2	S1841H	Neutral	0.701
BRCA1	P38398-1.2	S1841I	Neutral	0.658
BRCA1	P38398-1.2	S1841K	Neutral	0.743
BRCA1	P38398-1.2	S1841L	Neutral	0.658
BRCA1	P38398-1.2	S1841M	Neutral	0.701
BRCA1	P38398-1.2	S1841N	Neutral	0.786
BRCA1	P38398-1.2	S1841P	Neutral	0.701
BRCA1	P38398-1.2	S1841Q	Neutral	0.743
BRCA1	P38398-1.2	S1841R	Neutral	0.701
BRCA1	P38398-1.2	S1841T	Neutral	0.786
BRCA1	P38398-1.2	S1841V	Neutral	0.658
BRCA1	P38398-1.2	S1841W	Neutral	0.615
BRCA1	P38398-1.2	S1841Y	Neutral	0.658
BRCA1	P38398-1.2	V1842A	Neutral	0.793
BRCA1	P38398-1.2	V1842C	Neutral	0.75
BRCA1	P38398-1.2	V1842D	Neutral	0.665
BRCA1	P38398-1.2	V1842E	Neutral	0.708
BRCA1	P38398-1.2	V1842F	Neutral	0.75
BRCA1	P38398-1.2	V1842G	Neutral	0.665
BRCA1	P38398-1.2	V1842H	Neutral	0.665
BRCA1	P38398-1.2	V1842I	Neutral	0.921
BRCA1	P38398-1.2	V1842K	Neutral	0.708
BRCA1	P38398-1.2	V1842L	Neutral	0.836
BRCA1	P38398-1.2	V1842M	Neutral	0.836
BRCA1	P38398-1.2	V1842N	Neutral	0.665
BRCA1	P38398-1.2	V1842P	Neutral	0.708
BRCA1	P38398-1.2	V1842Q	Neutral	0.708
BRCA1	P38398-1.2	V1842R	Neutral	0.665
BRCA1	P38398-1.2	V1842S	Neutral	0.708
BRCA1	P38398-1.2	V1842T	Neutral	0.793
BRCA1	P38398-1.2	V1842W	Neutral	0.665
BRCA1	P38398-1.2	V1842Y	Neutral	0.75
BRCA1	P38398-1.2	A1843C	Neutral	0.591
BRCA1	P38398-1.2	A1843D	Pathogenic	0.506
BRCA1	P38398-1.2	A1843E	Neutral	0.549
BRCA1	P38398-1.2	A1843F	Pathogenic	0.506
BRCA1	P38398-1.2	A1843G	Neutral	0.591
BRCA1	P38398-1.2	A1843H	Pathogenic	0.506
BRCA1	P38398-1.2	A1843I	Neutral	0.549
BRCA1	P38398-1.2	A1843K	Neutral	0.549
BRCA1	P38398-1.2	A1843L	Neutral	0.549
BRCA1	P38398-1.2	A1843M	Neutral	0.549
BRCA1	P38398-1.2	A1843N	Pathogenic	0.506
BRCA1	P38398-1.2	A1843P	Neutral	0.549
BRCA1	P38398-1.2	A1843Q	Neutral	0.549
BRCA1	P38398-1.2	A1843R	Neutral	0.549
BRCA1	P38398-1.2	A1843S	Neutral	0.634
BRCA1	P38398-1.2	A1843T	Neutral	0.591
BRCA1	P38398-1.2	A1843V	Neutral	0.591
BRCA1	P38398-1.2	A1843W	Pathogenic	0.464
BRCA1	P38398-1.2	A1843Y	Pathogenic	0.506
BRCA1	P38398-1.2	L1844A	Neutral	1.028
BRCA1	P38398-1.2	L1844C	Neutral	1.028
BRCA1	P38398-1.2	L1844D	Neutral	0.9
BRCA1	P38398-1.2	L1844E	Neutral	0.943
BRCA1	P38398-1.2	L1844F	Neutral	1.07
BRCA1	P38398-1.2	L1844G	Neutral	0.9
BRCA1	P38398-1.2	L1844H	Neutral	0.943
BRCA1	P38398-1.2	L1844I	Neutral	1.155
BRCA1	P38398-1.2	L1844K	Neutral	0.985
BRCA1	P38398-1.2	L1844M	Neutral	1.155
BRCA1	P38398-1.2	L1844N	Neutral	0.943
BRCA1	P38398-1.2	L1844P	Neutral	0.943
BRCA1	P38398-1.2	L1844Q	Neutral	0.985
BRCA1	P38398-1.2	L1844R	Neutral	0.985
BRCA1	P38398-1.2	L1844S	Neutral	0.985
BRCA1	P38398-1.2	L1844T	Neutral	1.028
BRCA1	P38398-1.2	L1844V	Neutral	1.113
BRCA1	P38398-1.2	L1844W	Neutral	0.985
BRCA1	P38398-1.2	L1844Y	Neutral	1.028
BRCA1	P38398-1.2	Y1845A	Pathogenic	0.155
BRCA1	P38398-1.2	Y1845C	Pathogenic	0.155
BRCA1	P38398-1.2	Y1845D	Pathogenic	0.113
BRCA1	P38398-1.2	Y1845E	Pathogenic	0.155
BRCA1	P38398-1.2	Y1845F	Pathogenic	0.368
BRCA1	P38398-1.2	Y1845G	Pathogenic	0.113
BRCA1	P38398-1.2	Y1845H	Pathogenic	0.326
BRCA1	P38398-1.2	Y1845I	Pathogenic	0.198
BRCA1	P38398-1.2	Y1845K	Pathogenic	0.155
BRCA1	P38398-1.2	Y1845L	Pathogenic	0.198
BRCA1	P38398-1.2	Y1845M	Pathogenic	0.198
BRCA1	P38398-1.2	Y1845N	Pathogenic	0.155
BRCA1	P38398-1.2	Y1845P	Pathogenic	0.113
BRCA1	P38398-1.2	Y1845Q	Pathogenic	0.198
BRCA1	P38398-1.2	Y1845R	Pathogenic	0.155
BRCA1	P38398-1.2	Y1845S	Pathogenic	0.155
BRCA1	P38398-1.2	Y1845T	Pathogenic	0.155
BRCA1	P38398-1.2	Y1845V	Pathogenic	0.198
BRCA1	P38398-1.2	Y1845W	Pathogenic	0.326
BRCA1	P38398-1.2	Q1846A	Neutral	1.019
BRCA1	P38398-1.2	Q1846C	Neutral	0.934
BRCA1	P38398-1.2	Q1846D	Neutral	1.061
BRCA1	P38398-1.2	Q1846E	Neutral	1.147
BRCA1	P38398-1.2	Q1846F	Neutral	0.934
BRCA1	P38398-1.2	Q1846G	Neutral	0.976
BRCA1	P38398-1.2	Q1846H	Neutral	1.061
BRCA1	P38398-1.2	Q1846I	Neutral	0.934
BRCA1	P38398-1.2	Q1846K	Neutral	1.104
BRCA1	P38398-1.2	Q1846L	Neutral	0.976
BRCA1	P38398-1.2	Q1846M	Neutral	1.061
BRCA1	P38398-1.2	Q1846N	Neutral	1.061
BRCA1	P38398-1.2	Q1846P	Neutral	1.019
BRCA1	P38398-1.2	Q1846R	Neutral	1.104
BRCA1	P38398-1.2	Q1846S	Neutral	1.061
BRCA1	P38398-1.2	Q1846T	Neutral	1.019
BRCA1	P38398-1.2	Q1846V	Neutral	0.976
BRCA1	P38398-1.2	Q1846W	Neutral	0.976
BRCA1	P38398-1.2	Q1846Y	Neutral	1.019
BRCA1	P38398-1.2	C1847A	Neutral	0.777
BRCA1	P38398-1.2	C1847D	Neutral	0.649
BRCA1	P38398-1.2	C1847E	Neutral	0.607
BRCA1	P38398-1.2	C1847F	Neutral	0.692
BRCA1	P38398-1.2	C1847G	Neutral	0.649
BRCA1	P38398-1.2	C1847H	Neutral	0.649
BRCA1	P38398-1.2	C1847I	Neutral	0.735
BRCA1	P38398-1.2	C1847K	Neutral	0.649
BRCA1	P38398-1.2	C1847L	Neutral	0.735
BRCA1	P38398-1.2	C1847M	Neutral	0.735
BRCA1	P38398-1.2	C1847N	Neutral	0.649
BRCA1	P38398-1.2	C1847P	Neutral	0.649
BRCA1	P38398-1.2	C1847Q	Neutral	0.649
BRCA1	P38398-1.2	C1847R	Neutral	0.649
BRCA1	P38398-1.2	C1847S	Neutral	0.735
BRCA1	P38398-1.2	C1847T	Neutral	0.735
BRCA1	P38398-1.2	C1847V	Neutral	0.735
BRCA1	P38398-1.2	C1847W	Neutral	0.692
BRCA1	P38398-1.2	C1847Y	Neutral	0.692
BRCA1	P38398-1.2	Q1848A	Neutral	0.57
BRCA1	P38398-1.2	Q1848C	Pathogenic	0.485
BRCA1	P38398-1.2	Q1848D	Neutral	0.613
BRCA1	P38398-1.2	Q1848E	Neutral	0.698
BRCA1	P38398-1.2	Q1848F	Pathogenic	0.485
BRCA1	P38398-1.2	Q1848G	Pathogenic	0.528
BRCA1	P38398-1.2	Q1848H	Neutral	0.613
BRCA1	P38398-1.2	Q1848I	Pathogenic	0.485
BRCA1	P38398-1.2	Q1848K	Neutral	0.655
BRCA1	P38398-1.2	Q1848L	Pathogenic	0.528
BRCA1	P38398-1.2	Q1848M	Neutral	0.613
BRCA1	P38398-1.2	Q1848N	Neutral	0.613
BRCA1	P38398-1.2	Q1848P	Neutral	0.57
BRCA1	P38398-1.2	Q1848R	Neutral	0.655
BRCA1	P38398-1.2	Q1848S	Neutral	0.613
BRCA1	P38398-1.2	Q1848T	Neutral	0.57
BRCA1	P38398-1.2	Q1848V	Pathogenic	0.528
BRCA1	P38398-1.2	Q1848W	Pathogenic	0.528
BRCA1	P38398-1.2	Q1848Y	Neutral	0.57
BRCA1	P38398-1.2	E1849A	Neutral	1.118
BRCA1	P38398-1.2	E1849C	Neutral	0.99
BRCA1	P38398-1.2	E1849D	Neutral	1.246
BRCA1	P38398-1.2	E1849F	Neutral	1.033
BRCA1	P38398-1.2	E1849G	Neutral	1.075
BRCA1	P38398-1.2	E1849H	Neutral	1.16
BRCA1	P38398-1.2	E1849I	Neutral	1.033
BRCA1	P38398-1.2	E1849K	Neutral	1.203
BRCA1	P38398-1.2	E1849L	Neutral	1.033
BRCA1	P38398-1.2	E1849M	Neutral	1.075
BRCA1	P38398-1.2	E1849N	Neutral	1.16
BRCA1	P38398-1.2	E1849P	Neutral	1.118
BRCA1	P38398-1.2	E1849Q	Neutral	1.246
BRCA1	P38398-1.2	E1849R	Neutral	1.16
BRCA1	P38398-1.2	E1849S	Neutral	1.16
BRCA1	P38398-1.2	E1849T	Neutral	1.118
BRCA1	P38398-1.2	E1849V	Neutral	1.075
BRCA1	P38398-1.2	E1849W	Neutral	1.033
BRCA1	P38398-1.2	E1849Y	Neutral	1.075
BRCA1	P38398-1.2	L1850A	Neutral	0.863
BRCA1	P38398-1.2	L1850C	Neutral	0.863
BRCA1	P38398-1.2	L1850D	Neutral	0.735
BRCA1	P38398-1.2	L1850E	Neutral	0.777
BRCA1	P38398-1.2	L1850F	Neutral	0.905
BRCA1	P38398-1.2	L1850G	Neutral	0.735
BRCA1	P38398-1.2	L1850H	Neutral	0.777
BRCA1	P38398-1.2	L1850I	Neutral	0.99
BRCA1	P38398-1.2	L1850K	Neutral	0.82
BRCA1	P38398-1.2	L1850M	Neutral	0.99
BRCA1	P38398-1.2	L1850N	Neutral	0.777
BRCA1	P38398-1.2	L1850P	Neutral	0.777
BRCA1	P38398-1.2	L1850Q	Neutral	0.82
BRCA1	P38398-1.2	L1850R	Neutral	0.82
BRCA1	P38398-1.2	L1850S	Neutral	0.82
BRCA1	P38398-1.2	L1850T	Neutral	0.863
BRCA1	P38398-1.2	L1850V	Neutral	0.948
BRCA1	P38398-1.2	L1850W	Neutral	0.82
BRCA1	P38398-1.2	L1850Y	Neutral	0.863
BRCA1	P38398-1.2	D1851A	Neutral	0.715
BRCA1	P38398-1.2	D1851C	Neutral	0.672
BRCA1	P38398-1.2	D1851E	Neutral	0.885
BRCA1	P38398-1.2	D1851F	Neutral	0.672
BRCA1	P38398-1.2	D1851G	Neutral	0.757
BRCA1	P38398-1.2	D1851H	Neutral	0.757
BRCA1	P38398-1.2	D1851I	Neutral	0.672
BRCA1	P38398-1.2	D1851K	Neutral	0.757
BRCA1	P38398-1.2	D1851L	Neutral	0.63
BRCA1	P38398-1.2	D1851M	Neutral	0.672
BRCA1	P38398-1.2	D1851N	Neutral	0.842
BRCA1	P38398-1.2	D1851P	Neutral	0.757
BRCA1	P38398-1.2	D1851Q	Neutral	0.8
BRCA1	P38398-1.2	D1851R	Neutral	0.715
BRCA1	P38398-1.2	D1851S	Neutral	0.8
BRCA1	P38398-1.2	D1851T	Neutral	0.757
BRCA1	P38398-1.2	D1851V	Neutral	0.672
BRCA1	P38398-1.2	D1851W	Neutral	0.63
BRCA1	P38398-1.2	D1851Y	Neutral	0.672
BRCA1	P38398-1.2	T1852A	Neutral	1.041
BRCA1	P38398-1.2	T1852C	Neutral	0.998
BRCA1	P38398-1.2	T1852D	Neutral	0.998
BRCA1	P38398-1.2	T1852E	Neutral	0.998
BRCA1	P38398-1.2	T1852F	Neutral	0.955
BRCA1	P38398-1.2	T1852G	Neutral	0.955
BRCA1	P38398-1.2	T1852H	Neutral	0.955
BRCA1	P38398-1.2	T1852I	Neutral	0.998
BRCA1	P38398-1.2	T1852K	Neutral	0.998
BRCA1	P38398-1.2	T1852L	Neutral	0.998
BRCA1	P38398-1.2	T1852M	Neutral	0.998
BRCA1	P38398-1.2	T1852N	Neutral	1.041
BRCA1	P38398-1.2	T1852P	Neutral	0.998
BRCA1	P38398-1.2	T1852Q	Neutral	0.998
BRCA1	P38398-1.2	T1852R	Neutral	0.998
BRCA1	P38398-1.2	T1852S	Neutral	1.083
BRCA1	P38398-1.2	T1852V	Neutral	1.041
BRCA1	P38398-1.2	T1852W	Neutral	0.955
BRCA1	P38398-1.2	T1852Y	Neutral	0.955
BRCA1	P38398-1.2	Y1853A	Pathogenic	0.048
BRCA1	P38398-1.2	Y1853C	Pathogenic	0.048
BRCA1	P38398-1.2	Y1853D	Pathogenic	0.005
BRCA1	P38398-1.2	Y1853E	Pathogenic	0.048
BRCA1	P38398-1.2	Y1853F	Pathogenic	0.26
BRCA1	P38398-1.2	Y1853G	Pathogenic	0.005
BRCA1	P38398-1.2	Y1853H	Pathogenic	0.218
BRCA1	P38398-1.2	Y1853I	Pathogenic	0.09
BRCA1	P38398-1.2	Y1853K	Pathogenic	0.048
BRCA1	P38398-1.2	Y1853L	Pathogenic	0.09
BRCA1	P38398-1.2	Y1853M	Pathogenic	0.09
BRCA1	P38398-1.2	Y1853N	Pathogenic	0.048
BRCA1	P38398-1.2	Y1853P	Pathogenic	0.005
BRCA1	P38398-1.2	Y1853Q	Pathogenic	0.09
BRCA1	P38398-1.2	Y1853R	Pathogenic	0.048
BRCA1	P38398-1.2	Y1853S	Pathogenic	0.048
BRCA1	P38398-1.2	Y1853T	Pathogenic	0.048
BRCA1	P38398-1.2	Y1853V	Pathogenic	0.09
BRCA1	P38398-1.2	Y1853W	Pathogenic	0.218
BRCA1	P38398-1.2	L1854A	Neutral	0.703
BRCA1	P38398-1.2	L1854C	Neutral	0.703
BRCA1	P38398-1.2	L1854D	Neutral	0.576
BRCA1	P38398-1.2	L1854E	Neutral	0.618
BRCA1	P38398-1.2	L1854F	Neutral	0.746
BRCA1	P38398-1.2	L1854G	Neutral	0.576
BRCA1	P38398-1.2	L1854H	Neutral	0.618
BRCA1	P38398-1.2	L1854I	Neutral	0.831
BRCA1	P38398-1.2	L1854K	Neutral	0.661
BRCA1	P38398-1.2	L1854M	Neutral	0.831
BRCA1	P38398-1.2	L1854N	Neutral	0.618
BRCA1	P38398-1.2	L1854P	Neutral	0.618
BRCA1	P38398-1.2	L1854Q	Neutral	0.661
BRCA1	P38398-1.2	L1854R	Neutral	0.661
BRCA1	P38398-1.2	L1854S	Neutral	0.661
BRCA1	P38398-1.2	L1854T	Neutral	0.703
BRCA1	P38398-1.2	L1854V	Neutral	0.789
BRCA1	P38398-1.2	L1854W	Neutral	0.661
BRCA1	P38398-1.2	L1854Y	Neutral	0.703
BRCA1	P38398-1.2	I1855A	Neutral	0.934
BRCA1	P38398-1.2	I1855C	Neutral	0.934
BRCA1	P38398-1.2	I1855D	Neutral	0.849
BRCA1	P38398-1.2	I1855E	Neutral	0.849
BRCA1	P38398-1.2	I1855F	Neutral	0.977
BRCA1	P38398-1.2	I1855G	Neutral	0.806
BRCA1	P38398-1.2	I1855H	Neutral	0.849
BRCA1	P38398-1.2	I1855K	Neutral	0.849
BRCA1	P38398-1.2	I1855L	Neutral	1.062
BRCA1	P38398-1.2	I1855M	Neutral	1.019
BRCA1	P38398-1.2	I1855N	Neutral	0.849
BRCA1	P38398-1.2	I1855P	Neutral	0.849
BRCA1	P38398-1.2	I1855Q	Neutral	0.849
BRCA1	P38398-1.2	I1855R	Neutral	0.849
BRCA1	P38398-1.2	I1855S	Neutral	0.891
BRCA1	P38398-1.2	I1855T	Neutral	0.934
BRCA1	P38398-1.2	I1855V	Neutral	1.104
BRCA1	P38398-1.2	I1855W	Neutral	0.849
BRCA1	P38398-1.2	I1855Y	Neutral	0.934
BRCA1	P38398-1.2	P1856A	Neutral	1.092
BRCA1	P38398-1.2	P1856C	Neutral	1.007
BRCA1	P38398-1.2	P1856D	Neutral	1.092
BRCA1	P38398-1.2	P1856E	Neutral	1.092
BRCA1	P38398-1.2	P1856F	Neutral	0.964
BRCA1	P38398-1.2	P1856G	Neutral	1.049
BRCA1	P38398-1.2	P1856H	Neutral	1.049
BRCA1	P38398-1.2	P1856I	Neutral	1.007
BRCA1	P38398-1.2	P1856K	Neutral	1.092
BRCA1	P38398-1.2	P1856L	Neutral	1.007
BRCA1	P38398-1.2	P1856M	Neutral	1.049
BRCA1	P38398-1.2	P1856N	Neutral	1.049
BRCA1	P38398-1.2	P1856Q	Neutral	1.092
BRCA1	P38398-1.2	P1856R	Neutral	1.049
BRCA1	P38398-1.2	P1856S	Neutral	1.092
BRCA1	P38398-1.2	P1856T	Neutral	1.092
BRCA1	P38398-1.2	P1856V	Neutral	1.049
BRCA1	P38398-1.2	P1856W	Neutral	0.964
BRCA1	P38398-1.2	P1856Y	Neutral	1.007
BRCA1	P38398-1.2	Q1857A	Neutral	1.003
BRCA1	P38398-1.2	Q1857C	Neutral	0.918
BRCA1	P38398-1.2	Q1857D	Neutral	1.045
BRCA1	P38398-1.2	Q1857E	Neutral	1.131
BRCA1	P38398-1.2	Q1857F	Neutral	0.918
BRCA1	P38398-1.2	Q1857G	Neutral	0.96
BRCA1	P38398-1.2	Q1857H	Neutral	1.045
BRCA1	P38398-1.2	Q1857I	Neutral	0.918
BRCA1	P38398-1.2	Q1857K	Neutral	1.088
BRCA1	P38398-1.2	Q1857L	Neutral	0.96
BRCA1	P38398-1.2	Q1857M	Neutral	1.045
BRCA1	P38398-1.2	Q1857N	Neutral	1.045
BRCA1	P38398-1.2	Q1857P	Neutral	1.003
BRCA1	P38398-1.2	Q1857R	Neutral	1.088
BRCA1	P38398-1.2	Q1857S	Neutral	1.045
BRCA1	P38398-1.2	Q1857T	Neutral	1.003
BRCA1	P38398-1.2	Q1857V	Neutral	0.96
BRCA1	P38398-1.2	Q1857W	Neutral	0.96
BRCA1	P38398-1.2	Q1857Y	Neutral	1.003
BRCA1	P38398-1.2	I1858A	Neutral	1.014
BRCA1	P38398-1.2	I1858C	Neutral	1.014
BRCA1	P38398-1.2	I1858D	Neutral	0.929
BRCA1	P38398-1.2	I1858E	Neutral	0.929
BRCA1	P38398-1.2	I1858F	Neutral	1.057
BRCA1	P38398-1.2	I1858G	Neutral	0.886
BRCA1	P38398-1.2	I1858H	Neutral	0.929
BRCA1	P38398-1.2	I1858K	Neutral	0.929
BRCA1	P38398-1.2	I1858L	Neutral	1.142
BRCA1	P38398-1.2	I1858M	Neutral	1.099
BRCA1	P38398-1.2	I1858N	Neutral	0.929
BRCA1	P38398-1.2	I1858P	Neutral	0.929
BRCA1	P38398-1.2	I1858Q	Neutral	0.929
BRCA1	P38398-1.2	I1858R	Neutral	0.929
BRCA1	P38398-1.2	I1858S	Neutral	0.971
BRCA1	P38398-1.2	I1858T	Neutral	1.014
BRCA1	P38398-1.2	I1858V	Neutral	1.184
BRCA1	P38398-1.2	I1858W	Neutral	0.929
BRCA1	P38398-1.2	I1858Y	Neutral	1.014
BRCA1	P38398-1.2	P1859A	Neutral	1.085
BRCA1	P38398-1.2	P1859C	Neutral	1.0
BRCA1	P38398-1.2	P1859D	Neutral	1.085
BRCA1	P38398-1.2	P1859E	Neutral	1.085
BRCA1	P38398-1.2	P1859F	Neutral	0.957
BRCA1	P38398-1.2	P1859G	Neutral	1.042
BRCA1	P38398-1.2	P1859H	Neutral	1.042
BRCA1	P38398-1.2	P1859I	Neutral	1.0
BRCA1	P38398-1.2	P1859K	Neutral	1.085
BRCA1	P38398-1.2	P1859L	Neutral	1.0
BRCA1	P38398-1.2	P1859M	Neutral	1.042
BRCA1	P38398-1.2	P1859N	Neutral	1.042
BRCA1	P38398-1.2	P1859Q	Neutral	1.085
BRCA1	P38398-1.2	P1859R	Neutral	1.042
BRCA1	P38398-1.2	P1859S	Neutral	1.085
BRCA1	P38398-1.2	P1859T	Neutral	1.085
BRCA1	P38398-1.2	P1859V	Neutral	1.042
BRCA1	P38398-1.2	P1859W	Neutral	0.957
BRCA1	P38398-1.2	P1859Y	Neutral	1.0