Gene	UniProt	Variant	Prediction	Score
MEN1	O00255-1.4	M1A	Pathogenic	0.996
MEN1	O00255-1.4	M1C	Pathogenic	0.949
MEN1	O00255-1.4	M1D	Pathogenic	0.996
MEN1	O00255-1.4	M1E	Pathogenic	0.98
MEN1	O00255-1.4	M1F	Pathogenic	0.792
MEN1	O00255-1.4	M1G	Pathogenic	0.999
MEN1	O00255-1.4	M1H	Pathogenic	0.877
MEN1	O00255-1.4	M1I	Pathogenic	0.618
MEN1	O00255-1.4	M1K	Pathogenic	0.984
MEN1	O00255-1.4	M1L	Pathogenic	0.563
MEN1	O00255-1.4	M1N	Pathogenic	0.992
MEN1	O00255-1.4	M1P	Pathogenic	0.957
MEN1	O00255-1.4	M1Q	Pathogenic	0.938
MEN1	O00255-1.4	M1R	Pathogenic	0.994
MEN1	O00255-1.4	M1S	Pathogenic	0.996
MEN1	O00255-1.4	M1T	Pathogenic	0.973
MEN1	O00255-1.4	M1V	Pathogenic	0.731
MEN1	O00255-1.4	M1W	Pathogenic	0.986
MEN1	O00255-1.4	M1Y	Pathogenic	0.8
MEN1	O00255-1.4	G2A	Pathogenic	0.537
MEN1	O00255-1.4	G2C	Pathogenic	0.945
MEN1	O00255-1.4	G2D	Pathogenic	0.94
MEN1	O00255-1.4	G2E	Pathogenic	0.981
MEN1	O00255-1.4	G2F	Pathogenic	1.0
MEN1	O00255-1.4	G2H	Pathogenic	0.978
MEN1	O00255-1.4	G2I	Pathogenic	0.999
MEN1	O00255-1.4	G2K	Pathogenic	0.998
MEN1	O00255-1.4	G2L	Pathogenic	0.999
MEN1	O00255-1.4	G2M	Pathogenic	0.998
MEN1	O00255-1.4	G2N	Pathogenic	0.942
MEN1	O00255-1.4	G2P	Pathogenic	0.934
MEN1	O00255-1.4	G2Q	Pathogenic	0.974
MEN1	O00255-1.4	G2R	Pathogenic	0.999
MEN1	O00255-1.4	G2S	Pathogenic	0.539
MEN1	O00255-1.4	G2T	Pathogenic	0.894
MEN1	O00255-1.4	G2V	Pathogenic	0.99
MEN1	O00255-1.4	G2W	Pathogenic	1.0
MEN1	O00255-1.4	G2Y	Pathogenic	0.999
MEN1	O00255-1.4	L3A	Pathogenic	0.865
MEN1	O00255-1.4	L3C	Neutral	0.342
MEN1	O00255-1.4	L3D	Pathogenic	0.88
MEN1	O00255-1.4	L3E	Pathogenic	0.593
MEN1	O00255-1.4	L3F	Neutral	0.023
MEN1	O00255-1.4	L3G	Pathogenic	0.981
MEN1	O00255-1.4	L3H	Neutral	0.176
MEN1	O00255-1.4	L3I	Neutral	0.009
MEN1	O00255-1.4	L3K	Pathogenic	0.643
MEN1	O00255-1.4	L3M	Neutral	0.017
MEN1	O00255-1.4	L3N	Pathogenic	0.784
MEN1	O00255-1.4	L3P	Neutral	0.4
MEN1	O00255-1.4	L3Q	Neutral	0.324
MEN1	O00255-1.4	L3R	Pathogenic	0.83
MEN1	O00255-1.4	L3S	Pathogenic	0.884
MEN1	O00255-1.4	L3T	Pathogenic	0.5
MEN1	O00255-1.4	L3V	Neutral	0.071
MEN1	O00255-1.4	L3W	Neutral	0.312
MEN1	O00255-1.4	L3Y	Neutral	0.101
MEN1	O00255-1.4	K4A	Pathogenic	0.579
MEN1	O00255-1.4	K4C	Pathogenic	0.528
MEN1	O00255-1.4	K4D	Neutral	0.038
MEN1	O00255-1.4	K4E	Neutral	0.011
MEN1	O00255-1.4	K4F	Neutral	0.096
MEN1	O00255-1.4	K4G	Pathogenic	0.785
MEN1	O00255-1.4	K4H	Neutral	0.022
MEN1	O00255-1.4	K4I	Neutral	0.199
MEN1	O00255-1.4	K4L	Neutral	0.165
MEN1	O00255-1.4	K4M	Neutral	0.08
MEN1	O00255-1.4	K4N	Neutral	0.033
MEN1	O00255-1.4	K4P	Neutral	0.324
MEN1	O00255-1.4	K4Q	Neutral	0.015
MEN1	O00255-1.4	K4R	Neutral	0.002
MEN1	O00255-1.4	K4S	Neutral	0.321
MEN1	O00255-1.4	K4T	Neutral	0.153
MEN1	O00255-1.4	K4V	Neutral	0.272
MEN1	O00255-1.4	K4W	Pathogenic	0.646
MEN1	O00255-1.4	K4Y	Neutral	0.039
MEN1	O00255-1.4	A5C	Neutral	0.008
MEN1	O00255-1.4	A5D	Neutral	0.025
MEN1	O00255-1.4	A5E	Neutral	0.07
MEN1	O00255-1.4	A5F	Pathogenic	0.57
MEN1	O00255-1.4	A5G	Neutral	0.004
MEN1	O00255-1.4	A5H	Neutral	0.043
MEN1	O00255-1.4	A5I	Neutral	0.359
MEN1	O00255-1.4	A5K	Neutral	0.481
MEN1	O00255-1.4	A5L	Neutral	0.322
MEN1	O00255-1.4	A5M	Neutral	0.182
MEN1	O00255-1.4	A5N	Neutral	0.028
MEN1	O00255-1.4	A5P	Neutral	0.008
MEN1	O00255-1.4	A5Q	Neutral	0.052
MEN1	O00255-1.4	A5R	Pathogenic	0.714
MEN1	O00255-1.4	A5S	Neutral	0.002
MEN1	O00255-1.4	A5T	Neutral	0.005
MEN1	O00255-1.4	A5V	Neutral	0.047
MEN1	O00255-1.4	A5W	Pathogenic	0.96
MEN1	O00255-1.4	A5Y	Neutral	0.351
MEN1	O00255-1.4	A6C	Neutral	0.016
MEN1	O00255-1.4	A6D	Neutral	0.048
MEN1	O00255-1.4	A6E	Neutral	0.128
MEN1	O00255-1.4	A6F	Pathogenic	0.722
MEN1	O00255-1.4	A6G	Neutral	0.009
MEN1	O00255-1.4	A6H	Neutral	0.081
MEN1	O00255-1.4	A6I	Pathogenic	0.524
MEN1	O00255-1.4	A6K	Pathogenic	0.645
MEN1	O00255-1.4	A6L	Neutral	0.482
MEN1	O00255-1.4	A6M	Neutral	0.303
MEN1	O00255-1.4	A6N	Neutral	0.053
MEN1	O00255-1.4	A6P	Neutral	0.015
MEN1	O00255-1.4	A6Q	Neutral	0.098
MEN1	O00255-1.4	A6R	Pathogenic	0.831
MEN1	O00255-1.4	A6S	Neutral	0.003
MEN1	O00255-1.4	A6T	Neutral	0.01
MEN1	O00255-1.4	A6V	Neutral	0.088
MEN1	O00255-1.4	A6W	Pathogenic	0.979
MEN1	O00255-1.4	A6Y	Pathogenic	0.514
MEN1	O00255-1.4	Q7A	Pathogenic	0.591
MEN1	O00255-1.4	Q7C	Pathogenic	0.541
MEN1	O00255-1.4	Q7D	Neutral	0.19
MEN1	O00255-1.4	Q7E	Neutral	0.042
MEN1	O00255-1.4	Q7F	Pathogenic	0.721
MEN1	O00255-1.4	Q7G	Pathogenic	0.794
MEN1	O00255-1.4	Q7H	Neutral	0.04
MEN1	O00255-1.4	Q7I	Pathogenic	0.538
MEN1	O00255-1.4	Q7K	Neutral	0.214
MEN1	O00255-1.4	Q7L	Neutral	0.481
MEN1	O00255-1.4	Q7M	Neutral	0.278
MEN1	O00255-1.4	Q7N	Neutral	0.11
MEN1	O00255-1.4	Q7P	Neutral	0.336
MEN1	O00255-1.4	Q7R	Neutral	0.424
MEN1	O00255-1.4	Q7S	Neutral	0.332
MEN1	O00255-1.4	Q7T	Neutral	0.16
MEN1	O00255-1.4	Q7V	Neutral	0.282
MEN1	O00255-1.4	Q7W	Pathogenic	0.977
MEN1	O00255-1.4	Q7Y	Neutral	0.484
MEN1	O00255-1.4	K8A	Pathogenic	0.994
MEN1	O00255-1.4	K8C	Pathogenic	0.993
MEN1	O00255-1.4	K8D	Pathogenic	0.827
MEN1	O00255-1.4	K8E	Pathogenic	0.578
MEN1	O00255-1.4	K8F	Pathogenic	0.928
MEN1	O00255-1.4	K8G	Pathogenic	0.998
MEN1	O00255-1.4	K8H	Pathogenic	0.733
MEN1	O00255-1.4	K8I	Pathogenic	0.968
MEN1	O00255-1.4	K8L	Pathogenic	0.96
MEN1	O00255-1.4	K8M	Pathogenic	0.913
MEN1	O00255-1.4	K8N	Pathogenic	0.803
MEN1	O00255-1.4	K8P	Pathogenic	0.983
MEN1	O00255-1.4	K8Q	Pathogenic	0.65
MEN1	O00255-1.4	K8R	Neutral	0.22
MEN1	O00255-1.4	K8S	Pathogenic	0.983
MEN1	O00255-1.4	K8T	Pathogenic	0.956
MEN1	O00255-1.4	K8V	Pathogenic	0.978
MEN1	O00255-1.4	K8W	Pathogenic	0.995
MEN1	O00255-1.4	K8Y	Pathogenic	0.831
MEN1	O00255-1.4	T9A	Neutral	0.013
MEN1	O00255-1.4	T9C	Neutral	0.01
MEN1	O00255-1.4	T9D	Neutral	0.011
MEN1	O00255-1.4	T9E	Neutral	0.025
MEN1	O00255-1.4	T9F	Neutral	0.348
MEN1	O00255-1.4	T9G	Neutral	0.078
MEN1	O00255-1.4	T9H	Neutral	0.015
MEN1	O00255-1.4	T9I	Neutral	0.184
MEN1	O00255-1.4	T9K	Neutral	0.24
MEN1	O00255-1.4	T9L	Neutral	0.161
MEN1	O00255-1.4	T9M	Neutral	0.082
MEN1	O00255-1.4	T9N	Neutral	0.009
MEN1	O00255-1.4	T9P	Neutral	0.005
MEN1	O00255-1.4	T9Q	Neutral	0.019
MEN1	O00255-1.4	T9R	Neutral	0.461
MEN1	O00255-1.4	T9S	Neutral	0.011
MEN1	O00255-1.4	T9V	Neutral	0.02
MEN1	O00255-1.4	T9W	Pathogenic	0.901
MEN1	O00255-1.4	T9Y	Neutral	0.179
MEN1	O00255-1.4	L10A	Pathogenic	0.884
MEN1	O00255-1.4	L10C	Neutral	0.381
MEN1	O00255-1.4	L10D	Pathogenic	0.897
MEN1	O00255-1.4	L10E	Pathogenic	0.633
MEN1	O00255-1.4	L10F	Neutral	0.027
MEN1	O00255-1.4	L10G	Pathogenic	0.984
MEN1	O00255-1.4	L10H	Neutral	0.202
MEN1	O00255-1.4	L10I	Neutral	0.011
MEN1	O00255-1.4	L10K	Pathogenic	0.68
MEN1	O00255-1.4	L10M	Neutral	0.02
MEN1	O00255-1.4	L10N	Pathogenic	0.811
MEN1	O00255-1.4	L10P	Neutral	0.441
MEN1	O00255-1.4	L10Q	Neutral	0.362
MEN1	O00255-1.4	L10R	Pathogenic	0.852
MEN1	O00255-1.4	L10S	Pathogenic	0.9
MEN1	O00255-1.4	L10T	Pathogenic	0.542
MEN1	O00255-1.4	L10V	Neutral	0.083
MEN1	O00255-1.4	L10W	Neutral	0.349
MEN1	O00255-1.4	L10Y	Neutral	0.117
MEN1	O00255-1.4	F11A	Pathogenic	1.0
MEN1	O00255-1.4	F11C	Pathogenic	0.999
MEN1	O00255-1.4	F11D	Pathogenic	1.0
MEN1	O00255-1.4	F11E	Pathogenic	1.0
MEN1	O00255-1.4	F11G	Pathogenic	1.0
MEN1	O00255-1.4	F11H	Pathogenic	0.998
MEN1	O00255-1.4	F11I	Pathogenic	0.959
MEN1	O00255-1.4	F11K	Pathogenic	0.999
MEN1	O00255-1.4	F11L	Pathogenic	0.963
MEN1	O00255-1.4	F11M	Pathogenic	0.983
MEN1	O00255-1.4	F11N	Pathogenic	1.0
MEN1	O00255-1.4	F11P	Pathogenic	1.0
MEN1	O00255-1.4	F11Q	Pathogenic	0.999
MEN1	O00255-1.4	F11R	Pathogenic	1.0
MEN1	O00255-1.4	F11S	Pathogenic	1.0
MEN1	O00255-1.4	F11T	Pathogenic	1.0
MEN1	O00255-1.4	F11V	Pathogenic	0.996
MEN1	O00255-1.4	F11W	Pathogenic	0.994
MEN1	O00255-1.4	F11Y	Pathogenic	0.981
MEN1	O00255-1.4	P12A	Pathogenic	0.96
MEN1	O00255-1.4	P12C	Pathogenic	0.839
MEN1	O00255-1.4	P12D	Pathogenic	0.964
MEN1	O00255-1.4	P12E	Pathogenic	0.988
MEN1	O00255-1.4	P12F	Pathogenic	0.998
MEN1	O00255-1.4	P12G	Pathogenic	0.994
MEN1	O00255-1.4	P12H	Pathogenic	0.98
MEN1	O00255-1.4	P12I	Pathogenic	0.995
MEN1	O00255-1.4	P12K	Pathogenic	0.999
MEN1	O00255-1.4	P12L	Pathogenic	0.994
MEN1	O00255-1.4	P12M	Pathogenic	0.986
MEN1	O00255-1.4	P12N	Pathogenic	0.969
MEN1	O00255-1.4	P12Q	Pathogenic	0.984
MEN1	O00255-1.4	P12R	Pathogenic	1.0
MEN1	O00255-1.4	P12S	Pathogenic	0.964
MEN1	O00255-1.4	P12T	Pathogenic	0.856
MEN1	O00255-1.4	P12V	Pathogenic	0.942
MEN1	O00255-1.4	P12W	Pathogenic	1.0
MEN1	O00255-1.4	P12Y	Pathogenic	0.994
MEN1	O00255-1.4	L13A	Pathogenic	0.964
MEN1	O00255-1.4	L13C	Pathogenic	0.686
MEN1	O00255-1.4	L13D	Pathogenic	0.969
MEN1	O00255-1.4	L13E	Pathogenic	0.86
MEN1	O00255-1.4	L13F	Neutral	0.09
MEN1	O00255-1.4	L13G	Pathogenic	0.995
MEN1	O00255-1.4	L13H	Neutral	0.473
MEN1	O00255-1.4	L13I	Neutral	0.038
MEN1	O00255-1.4	L13K	Pathogenic	0.883
MEN1	O00255-1.4	L13M	Neutral	0.066
MEN1	O00255-1.4	L13N	Pathogenic	0.938
MEN1	O00255-1.4	L13P	Pathogenic	0.737
MEN1	O00255-1.4	L13Q	Pathogenic	0.668
MEN1	O00255-1.4	L13R	Pathogenic	0.953
MEN1	O00255-1.4	L13S	Pathogenic	0.97
MEN1	O00255-1.4	L13T	Pathogenic	0.808
MEN1	O00255-1.4	L13V	Neutral	0.243
MEN1	O00255-1.4	L13W	Pathogenic	0.655
MEN1	O00255-1.4	L13Y	Neutral	0.32
MEN1	O00255-1.4	R14A	Pathogenic	0.99
MEN1	O00255-1.4	R14C	Pathogenic	0.988
MEN1	O00255-1.4	R14D	Pathogenic	0.759
MEN1	O00255-1.4	R14E	Neutral	0.474
MEN1	O00255-1.4	R14F	Pathogenic	0.888
MEN1	O00255-1.4	R14G	Pathogenic	0.996
MEN1	O00255-1.4	R14H	Pathogenic	0.616
MEN1	O00255-1.4	R14I	Pathogenic	0.949
MEN1	O00255-1.4	R14K	Neutral	0.061
MEN1	O00255-1.4	R14L	Pathogenic	0.936
MEN1	O00255-1.4	R14M	Pathogenic	0.866
MEN1	O00255-1.4	R14N	Pathogenic	0.716
MEN1	O00255-1.4	R14P	Pathogenic	0.974
MEN1	O00255-1.4	R14Q	Pathogenic	0.535
MEN1	O00255-1.4	R14S	Pathogenic	0.974
MEN1	O00255-1.4	R14T	Pathogenic	0.931
MEN1	O00255-1.4	R14V	Pathogenic	0.967
MEN1	O00255-1.4	R14W	Pathogenic	0.951
MEN1	O00255-1.4	R14Y	Pathogenic	0.554
MEN1	O00255-1.4	S15A	Neutral	0.022
MEN1	O00255-1.4	S15C	Neutral	0.113
MEN1	O00255-1.4	S15D	Neutral	0.098
MEN1	O00255-1.4	S15E	Neutral	0.253
MEN1	O00255-1.4	S15F	Pathogenic	0.951
MEN1	O00255-1.4	S15G	Neutral	0.056
MEN1	O00255-1.4	S15H	Neutral	0.258
MEN1	O00255-1.4	S15I	Pathogenic	0.897
MEN1	O00255-1.4	S15K	Pathogenic	0.807
MEN1	O00255-1.4	S15L	Pathogenic	0.881
MEN1	O00255-1.4	S15M	Pathogenic	0.765
MEN1	O00255-1.4	S15N	Neutral	0.102
MEN1	O00255-1.4	S15P	Neutral	0.1
MEN1	O00255-1.4	S15Q	Neutral	0.199
MEN1	O00255-1.4	S15R	Pathogenic	0.923
MEN1	O00255-1.4	S15T	Neutral	0.055
MEN1	O00255-1.4	S15V	Neutral	0.449
MEN1	O00255-1.4	S15W	Pathogenic	0.997
MEN1	O00255-1.4	S15Y	Pathogenic	0.888
MEN1	O00255-1.4	I16A	Pathogenic	0.997
MEN1	O00255-1.4	I16C	Pathogenic	0.969
MEN1	O00255-1.4	I16D	Pathogenic	0.998
MEN1	O00255-1.4	I16E	Pathogenic	0.989
MEN1	O00255-1.4	I16F	Pathogenic	0.517
MEN1	O00255-1.4	I16G	Pathogenic	1.0
MEN1	O00255-1.4	I16H	Pathogenic	0.928
MEN1	O00255-1.4	I16K	Pathogenic	0.991
MEN1	O00255-1.4	I16L	Neutral	0.325
MEN1	O00255-1.4	I16M	Pathogenic	0.523
MEN1	O00255-1.4	I16N	Pathogenic	0.995
MEN1	O00255-1.4	I16P	Pathogenic	0.976
MEN1	O00255-1.4	I16Q	Pathogenic	0.969
MEN1	O00255-1.4	I16R	Pathogenic	0.997
MEN1	O00255-1.4	I16S	Pathogenic	0.998
MEN1	O00255-1.4	I16T	Pathogenic	0.984
MEN1	O00255-1.4	I16V	Pathogenic	0.804
MEN1	O00255-1.4	I16W	Pathogenic	0.954
MEN1	O00255-1.4	I16Y	Pathogenic	0.872
MEN1	O00255-1.4	D17A	Neutral	0.443
MEN1	O00255-1.4	D17C	Neutral	0.379
MEN1	O00255-1.4	D17E	Neutral	0.079
MEN1	O00255-1.4	D17F	Pathogenic	0.977
MEN1	O00255-1.4	D17G	Pathogenic	0.653
MEN1	O00255-1.4	D17H	Neutral	0.413
MEN1	O00255-1.4	D17I	Pathogenic	0.949
MEN1	O00255-1.4	D17K	Neutral	0.453
MEN1	O00255-1.4	D17L	Pathogenic	0.944
MEN1	O00255-1.4	D17M	Pathogenic	0.881
MEN1	O00255-1.4	D17N	Neutral	0.035
MEN1	O00255-1.4	D17P	Neutral	0.207
MEN1	O00255-1.4	D17Q	Neutral	0.217
MEN1	O00255-1.4	D17R	Pathogenic	0.704
MEN1	O00255-1.4	D17S	Neutral	0.205
MEN1	O00255-1.4	D17T	Neutral	0.118
MEN1	O00255-1.4	D17V	Pathogenic	0.636
MEN1	O00255-1.4	D17W	Pathogenic	0.999
MEN1	O00255-1.4	D17Y	Pathogenic	0.944
MEN1	O00255-1.4	D18A	Neutral	0.197
MEN1	O00255-1.4	D18C	Neutral	0.159
MEN1	O00255-1.4	D18E	Neutral	0.026
MEN1	O00255-1.4	D18F	Pathogenic	0.928
MEN1	O00255-1.4	D18G	Neutral	0.367
MEN1	O00255-1.4	D18H	Neutral	0.179
MEN1	O00255-1.4	D18I	Pathogenic	0.852
MEN1	O00255-1.4	D18K	Neutral	0.204
MEN1	O00255-1.4	D18L	Pathogenic	0.839
MEN1	O00255-1.4	D18M	Pathogenic	0.696
MEN1	O00255-1.4	D18N	Neutral	0.011
MEN1	O00255-1.4	D18P	Neutral	0.075
MEN1	O00255-1.4	D18Q	Neutral	0.079
MEN1	O00255-1.4	D18R	Neutral	0.424
MEN1	O00255-1.4	D18S	Neutral	0.074
MEN1	O00255-1.4	D18T	Neutral	0.04
MEN1	O00255-1.4	D18V	Neutral	0.351
MEN1	O00255-1.4	D18W	Pathogenic	0.996
MEN1	O00255-1.4	D18Y	Pathogenic	0.84
MEN1	O00255-1.4	V19A	Pathogenic	0.934
MEN1	O00255-1.4	V19C	Pathogenic	0.549
MEN1	O00255-1.4	V19D	Pathogenic	0.942
MEN1	O00255-1.4	V19E	Pathogenic	0.854
MEN1	O00255-1.4	V19F	Pathogenic	0.827
MEN1	O00255-1.4	V19G	Pathogenic	0.991
MEN1	O00255-1.4	V19H	Pathogenic	0.777
MEN1	O00255-1.4	V19I	Pathogenic	0.629
MEN1	O00255-1.4	V19K	Pathogenic	0.986
MEN1	O00255-1.4	V19L	Pathogenic	0.618
MEN1	O00255-1.4	V19M	Neutral	0.43
MEN1	O00255-1.4	V19N	Pathogenic	0.895
MEN1	O00255-1.4	V19P	Pathogenic	0.595
MEN1	O00255-1.4	V19Q	Pathogenic	0.812
MEN1	O00255-1.4	V19R	Pathogenic	0.995
MEN1	O00255-1.4	V19S	Pathogenic	0.947
MEN1	O00255-1.4	V19T	Pathogenic	0.688
MEN1	O00255-1.4	V19W	Pathogenic	0.989
MEN1	O00255-1.4	V19Y	Pathogenic	0.818
MEN1	O00255-1.4	V20A	Pathogenic	0.965
MEN1	O00255-1.4	V20C	Pathogenic	0.703
MEN1	O00255-1.4	V20D	Pathogenic	0.969
MEN1	O00255-1.4	V20E	Pathogenic	0.919
MEN1	O00255-1.4	V20F	Pathogenic	0.903
MEN1	O00255-1.4	V20G	Pathogenic	0.996
MEN1	O00255-1.4	V20H	Pathogenic	0.871
MEN1	O00255-1.4	V20I	Pathogenic	0.767
MEN1	O00255-1.4	V20K	Pathogenic	0.993
MEN1	O00255-1.4	V20L	Pathogenic	0.759
MEN1	O00255-1.4	V20M	Pathogenic	0.595
MEN1	O00255-1.4	V20N	Pathogenic	0.943
MEN1	O00255-1.4	V20P	Pathogenic	0.741
MEN1	O00255-1.4	V20Q	Pathogenic	0.893
MEN1	O00255-1.4	V20R	Pathogenic	0.998
MEN1	O00255-1.4	V20S	Pathogenic	0.972
MEN1	O00255-1.4	V20T	Pathogenic	0.811
MEN1	O00255-1.4	V20W	Pathogenic	0.994
MEN1	O00255-1.4	V20Y	Pathogenic	0.897
MEN1	O00255-1.4	R21A	Pathogenic	0.863
MEN1	O00255-1.4	R21C	Pathogenic	0.837
MEN1	O00255-1.4	R21D	Neutral	0.162
MEN1	O00255-1.4	R21E	Neutral	0.053
MEN1	O00255-1.4	R21F	Neutral	0.328
MEN1	O00255-1.4	R21G	Pathogenic	0.944
MEN1	O00255-1.4	R21H	Neutral	0.09
MEN1	O00255-1.4	R21I	Pathogenic	0.532
MEN1	O00255-1.4	R21K	Neutral	0.004
MEN1	O00255-1.4	R21L	Neutral	0.476
MEN1	O00255-1.4	R21M	Neutral	0.285
MEN1	O00255-1.4	R21N	Neutral	0.135
MEN1	O00255-1.4	R21P	Pathogenic	0.7
MEN1	O00255-1.4	R21Q	Neutral	0.066
MEN1	O00255-1.4	R21S	Pathogenic	0.697
MEN1	O00255-1.4	R21T	Neutral	0.454
MEN1	O00255-1.4	R21V	Pathogenic	0.645
MEN1	O00255-1.4	R21W	Pathogenic	0.546
MEN1	O00255-1.4	R21Y	Neutral	0.071
MEN1	O00255-1.4	L22A	Pathogenic	0.979
MEN1	O00255-1.4	L22C	Pathogenic	0.793
MEN1	O00255-1.4	L22D	Pathogenic	0.982
MEN1	O00255-1.4	L22E	Pathogenic	0.915
MEN1	O00255-1.4	L22F	Neutral	0.147
MEN1	O00255-1.4	L22G	Pathogenic	0.997
MEN1	O00255-1.4	L22H	Pathogenic	0.611
MEN1	O00255-1.4	L22I	Neutral	0.064
MEN1	O00255-1.4	L22K	Pathogenic	0.93
MEN1	O00255-1.4	L22M	Neutral	0.111
MEN1	O00255-1.4	L22N	Pathogenic	0.964
MEN1	O00255-1.4	L22P	Pathogenic	0.831
MEN1	O00255-1.4	L22Q	Pathogenic	0.779
MEN1	O00255-1.4	L22R	Pathogenic	0.973
MEN1	O00255-1.4	L22S	Pathogenic	0.982
MEN1	O00255-1.4	L22T	Pathogenic	0.88
MEN1	O00255-1.4	L22V	Neutral	0.359
MEN1	O00255-1.4	L22W	Pathogenic	0.769
MEN1	O00255-1.4	L22Y	Neutral	0.452
MEN1	O00255-1.4	F23A	Pathogenic	1.0
MEN1	O00255-1.4	F23C	Pathogenic	0.999
MEN1	O00255-1.4	F23D	Pathogenic	1.0
MEN1	O00255-1.4	F23E	Pathogenic	1.0
MEN1	O00255-1.4	F23G	Pathogenic	1.0
MEN1	O00255-1.4	F23H	Pathogenic	0.998
MEN1	O00255-1.4	F23I	Pathogenic	0.957
MEN1	O00255-1.4	F23K	Pathogenic	0.999
MEN1	O00255-1.4	F23L	Pathogenic	0.961
MEN1	O00255-1.4	F23M	Pathogenic	0.982
MEN1	O00255-1.4	F23N	Pathogenic	1.0
MEN1	O00255-1.4	F23P	Pathogenic	0.999
MEN1	O00255-1.4	F23Q	Pathogenic	0.999
MEN1	O00255-1.4	F23R	Pathogenic	1.0
MEN1	O00255-1.4	F23S	Pathogenic	1.0
MEN1	O00255-1.4	F23T	Pathogenic	1.0
MEN1	O00255-1.4	F23V	Pathogenic	0.996
MEN1	O00255-1.4	F23W	Pathogenic	0.993
MEN1	O00255-1.4	F23Y	Pathogenic	0.979
MEN1	O00255-1.4	A24C	Neutral	0.006
MEN1	O00255-1.4	A24D	Neutral	0.017
MEN1	O00255-1.4	A24E	Neutral	0.049
MEN1	O00255-1.4	A24F	Neutral	0.476
MEN1	O00255-1.4	A24G	Neutral	0.003
MEN1	O00255-1.4	A24H	Neutral	0.03
MEN1	O00255-1.4	A24I	Neutral	0.278
MEN1	O00255-1.4	A24K	Neutral	0.388
MEN1	O00255-1.4	A24L	Neutral	0.246
MEN1	O00255-1.4	A24M	Neutral	0.132
MEN1	O00255-1.4	A24N	Neutral	0.019
MEN1	O00255-1.4	A24P	Neutral	0.005
MEN1	O00255-1.4	A24Q	Neutral	0.037
MEN1	O00255-1.4	A24R	Pathogenic	0.632
MEN1	O00255-1.4	A24S	Neutral	0.001
MEN1	O00255-1.4	A24T	Neutral	0.003
MEN1	O00255-1.4	A24V	Neutral	0.033
MEN1	O00255-1.4	A24W	Pathogenic	0.943
MEN1	O00255-1.4	A24Y	Neutral	0.27
MEN1	O00255-1.4	A25C	Neutral	0.009
MEN1	O00255-1.4	A25D	Neutral	0.027
MEN1	O00255-1.4	A25E	Neutral	0.076
MEN1	O00255-1.4	A25F	Pathogenic	0.591
MEN1	O00255-1.4	A25G	Neutral	0.005
MEN1	O00255-1.4	A25H	Neutral	0.047
MEN1	O00255-1.4	A25I	Neutral	0.38
MEN1	O00255-1.4	A25K	Pathogenic	0.503
MEN1	O00255-1.4	A25L	Neutral	0.342
MEN1	O00255-1.4	A25M	Neutral	0.195
MEN1	O00255-1.4	A25N	Neutral	0.03
MEN1	O00255-1.4	A25P	Neutral	0.008
MEN1	O00255-1.4	A25Q	Neutral	0.057
MEN1	O00255-1.4	A25R	Pathogenic	0.732
MEN1	O00255-1.4	A25S	Neutral	0.002
MEN1	O00255-1.4	A25T	Neutral	0.005
MEN1	O00255-1.4	A25V	Neutral	0.051
MEN1	O00255-1.4	A25W	Pathogenic	0.963
MEN1	O00255-1.4	A25Y	Neutral	0.371
MEN1	O00255-1.4	E26A	Pathogenic	0.882
MEN1	O00255-1.4	E26C	Pathogenic	0.867
MEN1	O00255-1.4	E26D	Neutral	0.218
MEN1	O00255-1.4	E26F	Pathogenic	0.966
MEN1	O00255-1.4	E26G	Pathogenic	0.952
MEN1	O00255-1.4	E26H	Neutral	0.311
MEN1	O00255-1.4	E26I	Pathogenic	0.927
MEN1	O00255-1.4	E26K	Neutral	0.435
MEN1	O00255-1.4	E26L	Pathogenic	0.915
MEN1	O00255-1.4	E26M	Pathogenic	0.826
MEN1	O00255-1.4	E26N	Neutral	0.156
MEN1	O00255-1.4	E26P	Pathogenic	0.724
MEN1	O00255-1.4	E26Q	Neutral	0.144
MEN1	O00255-1.4	E26R	Pathogenic	0.688
MEN1	O00255-1.4	E26S	Pathogenic	0.721
MEN1	O00255-1.4	E26T	Neutral	0.498
MEN1	O00255-1.4	E26V	Pathogenic	0.671
MEN1	O00255-1.4	E26W	Pathogenic	0.998
MEN1	O00255-1.4	E26Y	Pathogenic	0.916
MEN1	O00255-1.4	L27A	Pathogenic	0.998
MEN1	O00255-1.4	L27C	Pathogenic	0.972
MEN1	O00255-1.4	L27D	Pathogenic	0.998
MEN1	O00255-1.4	L27E	Pathogenic	0.99
MEN1	O00255-1.4	L27F	Pathogenic	0.614
MEN1	O00255-1.4	L27G	Pathogenic	1.0
MEN1	O00255-1.4	L27H	Pathogenic	0.936
MEN1	O00255-1.4	L27I	Neutral	0.389
MEN1	O00255-1.4	L27K	Pathogenic	0.992
MEN1	O00255-1.4	L27M	Pathogenic	0.536
MEN1	O00255-1.4	L27N	Pathogenic	0.996
MEN1	O00255-1.4	L27P	Pathogenic	0.978
MEN1	O00255-1.4	L27Q	Pathogenic	0.97
MEN1	O00255-1.4	L27R	Pathogenic	0.997
MEN1	O00255-1.4	L27S	Pathogenic	0.998
MEN1	O00255-1.4	L27T	Pathogenic	0.986
MEN1	O00255-1.4	L27V	Pathogenic	0.838
MEN1	O00255-1.4	L27W	Pathogenic	0.969
MEN1	O00255-1.4	L27Y	Pathogenic	0.884
MEN1	O00255-1.4	G28A	Neutral	0.004
MEN1	O00255-1.4	G28C	Neutral	0.056
MEN1	O00255-1.4	G28D	Neutral	0.051
MEN1	O00255-1.4	G28E	Neutral	0.151
MEN1	O00255-1.4	G28F	Pathogenic	0.895
MEN1	O00255-1.4	G28H	Neutral	0.133
MEN1	O00255-1.4	G28I	Pathogenic	0.803
MEN1	O00255-1.4	G28K	Pathogenic	0.687
MEN1	O00255-1.4	G28L	Pathogenic	0.775
MEN1	O00255-1.4	G28M	Pathogenic	0.603
MEN1	O00255-1.4	G28N	Neutral	0.053
MEN1	O00255-1.4	G28P	Neutral	0.047
MEN1	O00255-1.4	G28Q	Neutral	0.116
MEN1	O00255-1.4	G28R	Pathogenic	0.856
MEN1	O00255-1.4	G28S	Neutral	0.004
MEN1	O00255-1.4	G28T	Neutral	0.028
MEN1	O00255-1.4	G28V	Neutral	0.264
MEN1	O00255-1.4	G28W	Pathogenic	0.993
MEN1	O00255-1.4	G28Y	Pathogenic	0.777
MEN1	O00255-1.4	R29A	Pathogenic	0.912
MEN1	O00255-1.4	R29C	Pathogenic	0.894
MEN1	O00255-1.4	R29D	Neutral	0.241
MEN1	O00255-1.4	R29E	Neutral	0.083
MEN1	O00255-1.4	R29F	Neutral	0.445
MEN1	O00255-1.4	R29G	Pathogenic	0.965
MEN1	O00255-1.4	R29H	Neutral	0.139
MEN1	O00255-1.4	R29I	Pathogenic	0.651
MEN1	O00255-1.4	R29K	Neutral	0.006
MEN1	O00255-1.4	R29L	Pathogenic	0.598
MEN1	O00255-1.4	R29M	Neutral	0.395
MEN1	O00255-1.4	R29N	Neutral	0.203
MEN1	O00255-1.4	R29P	Pathogenic	0.793
MEN1	O00255-1.4	R29Q	Neutral	0.104
MEN1	O00255-1.4	R29S	Pathogenic	0.79
MEN1	O00255-1.4	R29T	Pathogenic	0.577
MEN1	O00255-1.4	R29V	Pathogenic	0.748
MEN1	O00255-1.4	R29W	Pathogenic	0.663
MEN1	O00255-1.4	R29Y	Neutral	0.112
MEN1	O00255-1.4	E30A	Neutral	0.092
MEN1	O00255-1.4	E30C	Neutral	0.08
MEN1	O00255-1.4	E30D	Neutral	0.004
MEN1	O00255-1.4	E30F	Neutral	0.276
MEN1	O00255-1.4	E30G	Neutral	0.212
MEN1	O00255-1.4	E30H	Neutral	0.006
MEN1	O00255-1.4	E30I	Neutral	0.146
MEN1	O00255-1.4	E30K	Neutral	0.01
MEN1	O00255-1.4	E30L	Neutral	0.127
MEN1	O00255-1.4	E30M	Neutral	0.06
MEN1	O00255-1.4	E30N	Neutral	0.002
MEN1	O00255-1.4	E30P	Neutral	0.034
MEN1	O00255-1.4	E30Q	Neutral	0.002
MEN1	O00255-1.4	E30R	Neutral	0.029
MEN1	O00255-1.4	E30S	Neutral	0.034
MEN1	O00255-1.4	E30T	Neutral	0.013
MEN1	O00255-1.4	E30V	Neutral	0.027
MEN1	O00255-1.4	E30W	Pathogenic	0.867
MEN1	O00255-1.4	E30Y	Neutral	0.128
MEN1	O00255-1.4	E31A	Pathogenic	0.921
MEN1	O00255-1.4	E31C	Pathogenic	0.91
MEN1	O00255-1.4	E31D	Neutral	0.302
MEN1	O00255-1.4	E31F	Pathogenic	0.978
MEN1	O00255-1.4	E31G	Pathogenic	0.969
MEN1	O00255-1.4	E31H	Neutral	0.412
MEN1	O00255-1.4	E31I	Pathogenic	0.952
MEN1	O00255-1.4	E31K	Pathogenic	0.544
MEN1	O00255-1.4	E31L	Pathogenic	0.944
MEN1	O00255-1.4	E31M	Pathogenic	0.88
MEN1	O00255-1.4	E31N	Neutral	0.223
MEN1	O00255-1.4	E31P	Pathogenic	0.803
MEN1	O00255-1.4	E31Q	Neutral	0.207
MEN1	O00255-1.4	E31R	Pathogenic	0.774
MEN1	O00255-1.4	E31S	Pathogenic	0.8
MEN1	O00255-1.4	E31T	Pathogenic	0.606
MEN1	O00255-1.4	E31V	Pathogenic	0.76
MEN1	O00255-1.4	E31W	Pathogenic	0.999
MEN1	O00255-1.4	E31Y	Pathogenic	0.944
MEN1	O00255-1.4	P32A	Pathogenic	0.961
MEN1	O00255-1.4	P32C	Pathogenic	0.842
MEN1	O00255-1.4	P32D	Pathogenic	0.965
MEN1	O00255-1.4	P32E	Pathogenic	0.988
MEN1	O00255-1.4	P32F	Pathogenic	0.998
MEN1	O00255-1.4	P32G	Pathogenic	0.994
MEN1	O00255-1.4	P32H	Pathogenic	0.981
MEN1	O00255-1.4	P32I	Pathogenic	0.995
MEN1	O00255-1.4	P32K	Pathogenic	0.999
MEN1	O00255-1.4	P32L	Pathogenic	0.994
MEN1	O00255-1.4	P32M	Pathogenic	0.986
MEN1	O00255-1.4	P32N	Pathogenic	0.97
MEN1	O00255-1.4	P32Q	Pathogenic	0.984
MEN1	O00255-1.4	P32R	Pathogenic	1.0
MEN1	O00255-1.4	P32S	Pathogenic	0.965
MEN1	O00255-1.4	P32T	Pathogenic	0.858
MEN1	O00255-1.4	P32V	Pathogenic	0.944
MEN1	O00255-1.4	P32W	Pathogenic	1.0
MEN1	O00255-1.4	P32Y	Pathogenic	0.994
MEN1	O00255-1.4	D33A	Pathogenic	0.983
MEN1	O00255-1.4	D33C	Pathogenic	0.978
MEN1	O00255-1.4	D33E	Pathogenic	0.864
MEN1	O00255-1.4	D33F	Pathogenic	1.0
MEN1	O00255-1.4	D33G	Pathogenic	0.993
MEN1	O00255-1.4	D33H	Pathogenic	0.981
MEN1	O00255-1.4	D33I	Pathogenic	0.999
MEN1	O00255-1.4	D33K	Pathogenic	0.984
MEN1	O00255-1.4	D33L	Pathogenic	0.999
MEN1	O00255-1.4	D33M	Pathogenic	0.998
MEN1	O00255-1.4	D33N	Pathogenic	0.731
MEN1	O00255-1.4	D33P	Pathogenic	0.951
MEN1	O00255-1.4	D33Q	Pathogenic	0.954
MEN1	O00255-1.4	D33R	Pathogenic	0.994
MEN1	O00255-1.4	D33S	Pathogenic	0.95
MEN1	O00255-1.4	D33T	Pathogenic	0.908
MEN1	O00255-1.4	D33V	Pathogenic	0.992
MEN1	O00255-1.4	D33W	Pathogenic	1.0
MEN1	O00255-1.4	D33Y	Pathogenic	0.999
MEN1	O00255-1.4	L34A	Pathogenic	0.999
MEN1	O00255-1.4	L34C	Pathogenic	0.984
MEN1	O00255-1.4	L34D	Pathogenic	0.999
MEN1	O00255-1.4	L34E	Pathogenic	0.994
MEN1	O00255-1.4	L34F	Pathogenic	0.733
MEN1	O00255-1.4	L34G	Pathogenic	1.0
MEN1	O00255-1.4	L34H	Pathogenic	0.962
MEN1	O00255-1.4	L34I	Pathogenic	0.523
MEN1	O00255-1.4	L34K	Pathogenic	0.995
MEN1	O00255-1.4	L34M	Pathogenic	0.665
MEN1	O00255-1.4	L34N	Pathogenic	0.998
MEN1	O00255-1.4	L34P	Pathogenic	0.987
MEN1	O00255-1.4	L34Q	Pathogenic	0.983
MEN1	O00255-1.4	L34R	Pathogenic	0.998
MEN1	O00255-1.4	L34S	Pathogenic	0.999
MEN1	O00255-1.4	L34T	Pathogenic	0.992
MEN1	O00255-1.4	L34V	Pathogenic	0.899
MEN1	O00255-1.4	L34W	Pathogenic	0.981
MEN1	O00255-1.4	L34Y	Pathogenic	0.929
MEN1	O00255-1.4	V35A	Pathogenic	0.562
MEN1	O00255-1.4	V35C	Neutral	0.099
MEN1	O00255-1.4	V35D	Pathogenic	0.595
MEN1	O00255-1.4	V35E	Neutral	0.346
MEN1	O00255-1.4	V35F	Neutral	0.302
MEN1	O00255-1.4	V35G	Pathogenic	0.913
MEN1	O00255-1.4	V35H	Neutral	0.24
MEN1	O00255-1.4	V35I	Neutral	0.133
MEN1	O00255-1.4	V35K	Pathogenic	0.867
MEN1	O00255-1.4	V35L	Neutral	0.128
MEN1	O00255-1.4	V35M	Neutral	0.064
MEN1	O00255-1.4	V35N	Neutral	0.435
MEN1	O00255-1.4	V35P	Neutral	0.118
MEN1	O00255-1.4	V35Q	Neutral	0.281
MEN1	O00255-1.4	V35R	Pathogenic	0.949
MEN1	O00255-1.4	V35S	Pathogenic	0.618
MEN1	O00255-1.4	V35T	Neutral	0.167
MEN1	O00255-1.4	V35W	Pathogenic	0.893
MEN1	O00255-1.4	V35Y	Neutral	0.289
MEN1	O00255-1.4	L36A	Pathogenic	0.997
MEN1	O00255-1.4	L36C	Pathogenic	0.963
MEN1	O00255-1.4	L36D	Pathogenic	0.997
MEN1	O00255-1.4	L36E	Pathogenic	0.987
MEN1	O00255-1.4	L36F	Pathogenic	0.54
MEN1	O00255-1.4	L36G	Pathogenic	1.0
MEN1	O00255-1.4	L36H	Pathogenic	0.915
MEN1	O00255-1.4	L36I	Neutral	0.319
MEN1	O00255-1.4	L36K	Pathogenic	0.989
MEN1	O00255-1.4	L36M	Neutral	0.46
MEN1	O00255-1.4	L36N	Pathogenic	0.995
MEN1	O00255-1.4	L36P	Pathogenic	0.971
MEN1	O00255-1.4	L36Q	Pathogenic	0.96
MEN1	O00255-1.4	L36R	Pathogenic	0.996
MEN1	O00255-1.4	L36S	Pathogenic	0.997
MEN1	O00255-1.4	L36T	Pathogenic	0.98
MEN1	O00255-1.4	L36V	Pathogenic	0.793
MEN1	O00255-1.4	L36W	Pathogenic	0.958
MEN1	O00255-1.4	L36Y	Pathogenic	0.849
MEN1	O00255-1.4	L37A	Pathogenic	0.997
MEN1	O00255-1.4	L37C	Pathogenic	0.965
MEN1	O00255-1.4	L37D	Pathogenic	0.997
MEN1	O00255-1.4	L37E	Pathogenic	0.987
MEN1	O00255-1.4	L37F	Pathogenic	0.556
MEN1	O00255-1.4	L37G	Pathogenic	1.0
MEN1	O00255-1.4	L37H	Pathogenic	0.919
MEN1	O00255-1.4	L37I	Neutral	0.333
MEN1	O00255-1.4	L37K	Pathogenic	0.99
MEN1	O00255-1.4	L37M	Neutral	0.475
MEN1	O00255-1.4	L37N	Pathogenic	0.995
MEN1	O00255-1.4	L37P	Pathogenic	0.973
MEN1	O00255-1.4	L37Q	Pathogenic	0.962
MEN1	O00255-1.4	L37R	Pathogenic	0.996
MEN1	O00255-1.4	L37S	Pathogenic	0.998
MEN1	O00255-1.4	L37T	Pathogenic	0.982
MEN1	O00255-1.4	L37V	Pathogenic	0.803
MEN1	O00255-1.4	L37W	Pathogenic	0.96
MEN1	O00255-1.4	L37Y	Pathogenic	0.857
MEN1	O00255-1.4	S38A	Pathogenic	0.849
MEN1	O00255-1.4	S38C	Pathogenic	0.97
MEN1	O00255-1.4	S38D	Pathogenic	0.965
MEN1	O00255-1.4	S38E	Pathogenic	0.988
MEN1	O00255-1.4	S38F	Pathogenic	1.0
MEN1	O00255-1.4	S38G	Pathogenic	0.937
MEN1	O00255-1.4	S38H	Pathogenic	0.989
MEN1	O00255-1.4	S38I	Pathogenic	1.0
MEN1	O00255-1.4	S38K	Pathogenic	0.999
MEN1	O00255-1.4	S38L	Pathogenic	0.999
MEN1	O00255-1.4	S38M	Pathogenic	0.999
MEN1	O00255-1.4	S38N	Pathogenic	0.966
MEN1	O00255-1.4	S38P	Pathogenic	0.966
MEN1	O00255-1.4	S38Q	Pathogenic	0.984
MEN1	O00255-1.4	S38R	Pathogenic	1.0
MEN1	O00255-1.4	S38T	Pathogenic	0.936
MEN1	O00255-1.4	S38V	Pathogenic	0.995
MEN1	O00255-1.4	S38W	Pathogenic	1.0
MEN1	O00255-1.4	S38Y	Pathogenic	0.999
MEN1	O00255-1.4	L39A	Pathogenic	0.951
MEN1	O00255-1.4	L39C	Pathogenic	0.612
MEN1	O00255-1.4	L39D	Pathogenic	0.957
MEN1	O00255-1.4	L39E	Pathogenic	0.815
MEN1	O00255-1.4	L39F	Neutral	0.066
MEN1	O00255-1.4	L39G	Pathogenic	0.994
MEN1	O00255-1.4	L39H	Neutral	0.393
MEN1	O00255-1.4	L39I	Neutral	0.028
MEN1	O00255-1.4	L39K	Pathogenic	0.845
MEN1	O00255-1.4	L39M	Neutral	0.049
MEN1	O00255-1.4	L39N	Pathogenic	0.917
MEN1	O00255-1.4	L39P	Pathogenic	0.669
MEN1	O00255-1.4	L39Q	Pathogenic	0.592
MEN1	O00255-1.4	L39R	Pathogenic	0.937
MEN1	O00255-1.4	L39S	Pathogenic	0.958
MEN1	O00255-1.4	L39T	Pathogenic	0.752
MEN1	O00255-1.4	L39V	Neutral	0.188
MEN1	O00255-1.4	L39W	Pathogenic	0.578
MEN1	O00255-1.4	L39Y	Neutral	0.254
MEN1	O00255-1.4	V40A	Pathogenic	0.877
MEN1	O00255-1.4	V40C	Neutral	0.38
MEN1	O00255-1.4	V40D	Pathogenic	0.891
MEN1	O00255-1.4	V40E	Pathogenic	0.746
MEN1	O00255-1.4	V40F	Pathogenic	0.706
MEN1	O00255-1.4	V40G	Pathogenic	0.983
MEN1	O00255-1.4	V40H	Pathogenic	0.637
MEN1	O00255-1.4	V40I	Neutral	0.46
MEN1	O00255-1.4	V40K	Pathogenic	0.973
MEN1	O00255-1.4	V40L	Neutral	0.448
MEN1	O00255-1.4	V40M	Neutral	0.275
MEN1	O00255-1.4	V40N	Pathogenic	0.81
MEN1	O00255-1.4	V40P	Neutral	0.425
MEN1	O00255-1.4	V40Q	Pathogenic	0.684
MEN1	O00255-1.4	V40R	Pathogenic	0.99
MEN1	O00255-1.4	V40S	Pathogenic	0.9
MEN1	O00255-1.4	V40T	Pathogenic	0.526
MEN1	O00255-1.4	V40W	Pathogenic	0.979
MEN1	O00255-1.4	V40Y	Pathogenic	0.693
MEN1	O00255-1.4	L41A	Pathogenic	0.93
MEN1	O00255-1.4	L41C	Pathogenic	0.519
MEN1	O00255-1.4	L41D	Pathogenic	0.938
MEN1	O00255-1.4	L41E	Pathogenic	0.751
MEN1	O00255-1.4	L41F	Neutral	0.046
MEN1	O00255-1.4	L41G	Pathogenic	0.991
MEN1	O00255-1.4	L41H	Neutral	0.307
MEN1	O00255-1.4	L41I	Neutral	0.019
MEN1	O00255-1.4	L41K	Pathogenic	0.789
MEN1	O00255-1.4	L41M	Neutral	0.034
MEN1	O00255-1.4	L41N	Pathogenic	0.883
MEN1	O00255-1.4	L41P	Pathogenic	0.581
MEN1	O00255-1.4	L41Q	Neutral	0.499
MEN1	O00255-1.4	L41R	Pathogenic	0.91
MEN1	O00255-1.4	L41S	Pathogenic	0.94
MEN1	O00255-1.4	L41T	Pathogenic	0.675
MEN1	O00255-1.4	L41V	Neutral	0.136
MEN1	O00255-1.4	L41W	Neutral	0.484
MEN1	O00255-1.4	L41Y	Neutral	0.189
MEN1	O00255-1.4	G42A	Pathogenic	0.934
MEN1	O00255-1.4	G42C	Pathogenic	0.995
MEN1	O00255-1.4	G42D	Pathogenic	0.995
MEN1	O00255-1.4	G42E	Pathogenic	0.998
MEN1	O00255-1.4	G42F	Pathogenic	1.0
MEN1	O00255-1.4	G42H	Pathogenic	0.998
MEN1	O00255-1.4	G42I	Pathogenic	1.0
MEN1	O00255-1.4	G42K	Pathogenic	1.0
MEN1	O00255-1.4	G42L	Pathogenic	1.0
MEN1	O00255-1.4	G42M	Pathogenic	1.0
MEN1	O00255-1.4	G42N	Pathogenic	0.995
MEN1	O00255-1.4	G42P	Pathogenic	0.994
MEN1	O00255-1.4	G42Q	Pathogenic	0.998
MEN1	O00255-1.4	G42R	Pathogenic	1.0
MEN1	O00255-1.4	G42S	Pathogenic	0.934
MEN1	O00255-1.4	G42T	Pathogenic	0.99
MEN1	O00255-1.4	G42V	Pathogenic	0.999
MEN1	O00255-1.4	G42W	Pathogenic	1.0
MEN1	O00255-1.4	G42Y	Pathogenic	1.0
MEN1	O00255-1.4	F43A	Pathogenic	0.993
MEN1	O00255-1.4	F43C	Pathogenic	0.916
MEN1	O00255-1.4	F43D	Pathogenic	0.993
MEN1	O00255-1.4	F43E	Pathogenic	0.966
MEN1	O00255-1.4	F43G	Pathogenic	0.999
MEN1	O00255-1.4	F43H	Pathogenic	0.789
MEN1	O00255-1.4	F43I	Neutral	0.135
MEN1	O00255-1.4	F43K	Pathogenic	0.88
MEN1	O00255-1.4	F43L	Neutral	0.15
MEN1	O00255-1.4	F43M	Neutral	0.274
MEN1	O00255-1.4	F43N	Pathogenic	0.986
MEN1	O00255-1.4	F43P	Pathogenic	0.933
MEN1	O00255-1.4	F43Q	Pathogenic	0.91
MEN1	O00255-1.4	F43R	Pathogenic	0.952
MEN1	O00255-1.4	F43S	Pathogenic	0.993
MEN1	O00255-1.4	F43T	Pathogenic	0.954
MEN1	O00255-1.4	F43V	Pathogenic	0.629
MEN1	O00255-1.4	F43W	Pathogenic	0.52
MEN1	O00255-1.4	F43Y	Neutral	0.252
MEN1	O00255-1.4	V44A	Pathogenic	0.937
MEN1	O00255-1.4	V44C	Pathogenic	0.561
MEN1	O00255-1.4	V44D	Pathogenic	0.944
MEN1	O00255-1.4	V44E	Pathogenic	0.86
MEN1	O00255-1.4	V44F	Pathogenic	0.834
MEN1	O00255-1.4	V44G	Pathogenic	0.992
MEN1	O00255-1.4	V44H	Pathogenic	0.785
MEN1	O00255-1.4	V44I	Pathogenic	0.64
MEN1	O00255-1.4	V44K	Pathogenic	0.987
MEN1	O00255-1.4	V44L	Pathogenic	0.629
MEN1	O00255-1.4	V44M	Neutral	0.442
MEN1	O00255-1.4	V44N	Pathogenic	0.899
MEN1	O00255-1.4	V44P	Pathogenic	0.607
MEN1	O00255-1.4	V44Q	Pathogenic	0.819
MEN1	O00255-1.4	V44R	Pathogenic	0.995
MEN1	O00255-1.4	V44S	Pathogenic	0.949
MEN1	O00255-1.4	V44T	Pathogenic	0.698
MEN1	O00255-1.4	V44W	Pathogenic	0.99
MEN1	O00255-1.4	V44Y	Pathogenic	0.825
MEN1	O00255-1.4	E45A	Pathogenic	0.995
MEN1	O00255-1.4	E45C	Pathogenic	0.995
MEN1	O00255-1.4	E45D	Pathogenic	0.886
MEN1	O00255-1.4	E45F	Pathogenic	0.999
MEN1	O00255-1.4	E45G	Pathogenic	0.998
MEN1	O00255-1.4	E45H	Pathogenic	0.927
MEN1	O00255-1.4	E45I	Pathogenic	0.997
MEN1	O00255-1.4	E45K	Pathogenic	0.955
MEN1	O00255-1.4	E45L	Pathogenic	0.997
MEN1	O00255-1.4	E45M	Pathogenic	0.993
MEN1	O00255-1.4	E45N	Pathogenic	0.838
MEN1	O00255-1.4	E45P	Pathogenic	0.987
MEN1	O00255-1.4	E45Q	Pathogenic	0.824
MEN1	O00255-1.4	E45R	Pathogenic	0.984
MEN1	O00255-1.4	E45S	Pathogenic	0.986
MEN1	O00255-1.4	E45T	Pathogenic	0.965
MEN1	O00255-1.4	E45V	Pathogenic	0.983
MEN1	O00255-1.4	E45W	Pathogenic	1.0
MEN1	O00255-1.4	E45Y	Pathogenic	0.997
MEN1	O00255-1.4	H46A	Pathogenic	0.99
MEN1	O00255-1.4	H46C	Pathogenic	0.987
MEN1	O00255-1.4	H46D	Pathogenic	0.98
MEN1	O00255-1.4	H46E	Pathogenic	0.908
MEN1	O00255-1.4	H46F	Pathogenic	0.988
MEN1	O00255-1.4	H46G	Pathogenic	0.997
MEN1	O00255-1.4	H46I	Pathogenic	0.976
MEN1	O00255-1.4	H46K	Pathogenic	0.971
MEN1	O00255-1.4	H46L	Pathogenic	0.972
MEN1	O00255-1.4	H46M	Pathogenic	0.938
MEN1	O00255-1.4	H46N	Pathogenic	0.959
MEN1	O00255-1.4	H46P	Pathogenic	0.972
MEN1	O00255-1.4	H46Q	Pathogenic	0.776
MEN1	O00255-1.4	H46R	Pathogenic	0.989
MEN1	O00255-1.4	H46S	Pathogenic	0.983
MEN1	O00255-1.4	H46T	Pathogenic	0.928
MEN1	O00255-1.4	H46V	Pathogenic	0.964
MEN1	O00255-1.4	H46W	Pathogenic	0.999
MEN1	O00255-1.4	H46Y	Pathogenic	0.965
MEN1	O00255-1.4	F47A	Pathogenic	0.992
MEN1	O00255-1.4	F47C	Pathogenic	0.911
MEN1	O00255-1.4	F47D	Pathogenic	0.992
MEN1	O00255-1.4	F47E	Pathogenic	0.964
MEN1	O00255-1.4	F47G	Pathogenic	0.999
MEN1	O00255-1.4	F47H	Pathogenic	0.778
MEN1	O00255-1.4	F47I	Neutral	0.128
MEN1	O00255-1.4	F47K	Pathogenic	0.873
MEN1	O00255-1.4	F47L	Neutral	0.142
MEN1	O00255-1.4	F47M	Neutral	0.262
MEN1	O00255-1.4	F47N	Pathogenic	0.985
MEN1	O00255-1.4	F47P	Pathogenic	0.929
MEN1	O00255-1.4	F47Q	Pathogenic	0.904
MEN1	O00255-1.4	F47R	Pathogenic	0.949
MEN1	O00255-1.4	F47S	Pathogenic	0.993
MEN1	O00255-1.4	F47T	Pathogenic	0.952
MEN1	O00255-1.4	F47V	Pathogenic	0.615
MEN1	O00255-1.4	F47W	Pathogenic	0.505
MEN1	O00255-1.4	F47Y	Neutral	0.24
MEN1	O00255-1.4	L48A	Pathogenic	0.996
MEN1	O00255-1.4	L48C	Pathogenic	0.949
MEN1	O00255-1.4	L48D	Pathogenic	0.996
MEN1	O00255-1.4	L48E	Pathogenic	0.981
MEN1	O00255-1.4	L48F	Neutral	0.455
MEN1	O00255-1.4	L48G	Pathogenic	0.999
MEN1	O00255-1.4	L48H	Pathogenic	0.884
MEN1	O00255-1.4	L48I	Neutral	0.25
MEN1	O00255-1.4	L48K	Pathogenic	0.985
MEN1	O00255-1.4	L48M	Neutral	0.376
MEN1	O00255-1.4	L48N	Pathogenic	0.992
MEN1	O00255-1.4	L48P	Pathogenic	0.96
MEN1	O00255-1.4	L48Q	Pathogenic	0.945
MEN1	O00255-1.4	L48R	Pathogenic	0.994
MEN1	O00255-1.4	L48S	Pathogenic	0.996
MEN1	O00255-1.4	L48T	Pathogenic	0.973
MEN1	O00255-1.4	L48V	Pathogenic	0.731
MEN1	O00255-1.4	L48W	Pathogenic	0.942
MEN1	O00255-1.4	L48Y	Pathogenic	0.8
MEN1	O00255-1.4	A49C	Neutral	0.399
MEN1	O00255-1.4	A49D	Pathogenic	0.677
MEN1	O00255-1.4	A49E	Pathogenic	0.859
MEN1	O00255-1.4	A49F	Pathogenic	0.991
MEN1	O00255-1.4	A49G	Neutral	0.268
MEN1	O00255-1.4	A49H	Pathogenic	0.785
MEN1	O00255-1.4	A49I	Pathogenic	0.979
MEN1	O00255-1.4	A49K	Pathogenic	0.987
MEN1	O00255-1.4	A49L	Pathogenic	0.975
MEN1	O00255-1.4	A49M	Pathogenic	0.948
MEN1	O00255-1.4	A49N	Pathogenic	0.698
MEN1	O00255-1.4	A49P	Neutral	0.383
MEN1	O00255-1.4	A49Q	Pathogenic	0.818
MEN1	O00255-1.4	A49R	Pathogenic	0.995
MEN1	O00255-1.4	A49S	Neutral	0.122
MEN1	O00255-1.4	A49T	Neutral	0.29
MEN1	O00255-1.4	A49V	Pathogenic	0.801
MEN1	O00255-1.4	A49W	Pathogenic	0.999
MEN1	O00255-1.4	A49Y	Pathogenic	0.978
MEN1	O00255-1.4	V50A	Pathogenic	0.652
MEN1	O00255-1.4	V50C	Neutral	0.139
MEN1	O00255-1.4	V50D	Pathogenic	0.682
MEN1	O00255-1.4	V50E	Neutral	0.436
MEN1	O00255-1.4	V50F	Neutral	0.388
MEN1	O00255-1.4	V50G	Pathogenic	0.939
MEN1	O00255-1.4	V50H	Neutral	0.315
MEN1	O00255-1.4	V50I	Neutral	0.183
MEN1	O00255-1.4	V50K	Pathogenic	0.905
MEN1	O00255-1.4	V50L	Neutral	0.176
MEN1	O00255-1.4	V50M	Neutral	0.091
MEN1	O00255-1.4	V50N	Pathogenic	0.529
MEN1	O00255-1.4	V50P	Neutral	0.163
MEN1	O00255-1.4	V50Q	Neutral	0.363
MEN1	O00255-1.4	V50R	Pathogenic	0.965
MEN1	O00255-1.4	V50S	Pathogenic	0.702
MEN1	O00255-1.4	V50T	Neutral	0.226
MEN1	O00255-1.4	V50W	Pathogenic	0.924
MEN1	O00255-1.4	V50Y	Neutral	0.373
MEN1	O00255-1.4	N51A	Pathogenic	0.955
MEN1	O00255-1.4	N51C	Pathogenic	0.942
MEN1	O00255-1.4	N51D	Neutral	0.467
MEN1	O00255-1.4	N51E	Pathogenic	0.578
MEN1	O00255-1.4	N51F	Pathogenic	0.998
MEN1	O00255-1.4	N51G	Pathogenic	0.979
MEN1	O00255-1.4	N51H	Pathogenic	0.886
MEN1	O00255-1.4	N51I	Pathogenic	0.996
MEN1	O00255-1.4	N51K	Pathogenic	0.944
MEN1	O00255-1.4	N51L	Pathogenic	0.995
MEN1	O00255-1.4	N51M	Pathogenic	0.989
MEN1	O00255-1.4	N51P	Pathogenic	0.88
MEN1	O00255-1.4	N51Q	Pathogenic	0.777
MEN1	O00255-1.4	N51R	Pathogenic	0.979
MEN1	O00255-1.4	N51S	Pathogenic	0.865
MEN1	O00255-1.4	N51T	Pathogenic	0.711
MEN1	O00255-1.4	N51V	Pathogenic	0.956
MEN1	O00255-1.4	N51W	Pathogenic	1.0
MEN1	O00255-1.4	N51Y	Pathogenic	0.995
MEN1	O00255-1.4	R52A	Pathogenic	0.999
MEN1	O00255-1.4	R52C	Pathogenic	0.999
MEN1	O00255-1.4	R52D	Pathogenic	0.97
MEN1	O00255-1.4	R52E	Pathogenic	0.902
MEN1	O00255-1.4	R52F	Pathogenic	0.988
MEN1	O00255-1.4	R52G	Pathogenic	1.0
MEN1	O00255-1.4	R52H	Pathogenic	0.943
MEN1	O00255-1.4	R52I	Pathogenic	0.995
MEN1	O00255-1.4	R52K	Neutral	0.399
MEN1	O00255-1.4	R52L	Pathogenic	0.993
MEN1	O00255-1.4	R52M	Pathogenic	0.985
MEN1	O00255-1.4	R52N	Pathogenic	0.963
MEN1	O00255-1.4	R52P	Pathogenic	0.997
MEN1	O00255-1.4	R52Q	Pathogenic	0.922
MEN1	O00255-1.4	R52S	Pathogenic	0.997
MEN1	O00255-1.4	R52T	Pathogenic	0.993
MEN1	O00255-1.4	R52V	Pathogenic	0.997
MEN1	O00255-1.4	R52W	Pathogenic	0.995
MEN1	O00255-1.4	R52Y	Pathogenic	0.927
MEN1	O00255-1.4	V53A	Pathogenic	0.669
MEN1	O00255-1.4	V53C	Neutral	0.148
MEN1	O00255-1.4	V53D	Pathogenic	0.699
MEN1	O00255-1.4	V53E	Neutral	0.455
MEN1	O00255-1.4	V53F	Neutral	0.406
MEN1	O00255-1.4	V53G	Pathogenic	0.943
MEN1	O00255-1.4	V53H	Neutral	0.332
MEN1	O00255-1.4	V53I	Neutral	0.195
MEN1	O00255-1.4	V53K	Pathogenic	0.911
MEN1	O00255-1.4	V53L	Neutral	0.188
MEN1	O00255-1.4	V53M	Neutral	0.097
MEN1	O00255-1.4	V53N	Pathogenic	0.548
MEN1	O00255-1.4	V53P	Neutral	0.174
MEN1	O00255-1.4	V53Q	Neutral	0.381
MEN1	O00255-1.4	V53R	Pathogenic	0.967
MEN1	O00255-1.4	V53S	Pathogenic	0.718
MEN1	O00255-1.4	V53T	Neutral	0.24
MEN1	O00255-1.4	V53W	Pathogenic	0.93
MEN1	O00255-1.4	V53Y	Neutral	0.391
MEN1	O00255-1.4	I54A	Pathogenic	0.954
MEN1	O00255-1.4	I54C	Pathogenic	0.625
MEN1	O00255-1.4	I54D	Pathogenic	0.957
MEN1	O00255-1.4	I54E	Pathogenic	0.823
MEN1	O00255-1.4	I54F	Neutral	0.053
MEN1	O00255-1.4	I54G	Pathogenic	0.994
MEN1	O00255-1.4	I54H	Neutral	0.406
MEN1	O00255-1.4	I54K	Pathogenic	0.86
MEN1	O00255-1.4	I54L	Neutral	0.025
MEN1	O00255-1.4	I54M	Neutral	0.055
MEN1	O00255-1.4	I54N	Pathogenic	0.921
MEN1	O00255-1.4	I54P	Pathogenic	0.681
MEN1	O00255-1.4	I54Q	Pathogenic	0.62
MEN1	O00255-1.4	I54R	Pathogenic	0.943
MEN1	O00255-1.4	I54S	Pathogenic	0.961
MEN1	O00255-1.4	I54T	Pathogenic	0.762
MEN1	O00255-1.4	I54V	Neutral	0.178
MEN1	O00255-1.4	I54W	Pathogenic	0.525
MEN1	O00255-1.4	I54Y	Neutral	0.264
MEN1	O00255-1.4	P55A	Neutral	0.234
MEN1	O00255-1.4	P55C	Neutral	0.062
MEN1	O00255-1.4	P55D	Neutral	0.253
MEN1	O00255-1.4	P55E	Pathogenic	0.512
MEN1	O00255-1.4	P55F	Pathogenic	0.846
MEN1	O00255-1.4	P55G	Pathogenic	0.688
MEN1	O00255-1.4	P55H	Neutral	0.385
MEN1	O00255-1.4	P55I	Pathogenic	0.7
MEN1	O00255-1.4	P55K	Pathogenic	0.928
MEN1	O00255-1.4	P55L	Pathogenic	0.664
MEN1	O00255-1.4	P55M	Neutral	0.465
MEN1	O00255-1.4	P55N	Neutral	0.284
MEN1	O00255-1.4	P55Q	Neutral	0.436
MEN1	O00255-1.4	P55R	Pathogenic	0.974
MEN1	O00255-1.4	P55S	Neutral	0.254
MEN1	O00255-1.4	P55T	Neutral	0.069
MEN1	O00255-1.4	P55V	Neutral	0.171
MEN1	O00255-1.4	P55W	Pathogenic	0.99
MEN1	O00255-1.4	P55Y	Pathogenic	0.679
MEN1	O00255-1.4	T56A	Neutral	0.103
MEN1	O00255-1.4	T56C	Neutral	0.081
MEN1	O00255-1.4	T56D	Neutral	0.09
MEN1	O00255-1.4	T56E	Neutral	0.185
MEN1	O00255-1.4	T56F	Pathogenic	0.826
MEN1	O00255-1.4	T56G	Neutral	0.428
MEN1	O00255-1.4	T56H	Neutral	0.119
MEN1	O00255-1.4	T56I	Pathogenic	0.668
MEN1	O00255-1.4	T56K	Pathogenic	0.737
MEN1	O00255-1.4	T56L	Pathogenic	0.63
MEN1	O00255-1.4	T56M	Neutral	0.443
MEN1	O00255-1.4	T56N	Neutral	0.071
MEN1	O00255-1.4	T56P	Neutral	0.041
MEN1	O00255-1.4	T56Q	Neutral	0.144
MEN1	O00255-1.4	T56R	Pathogenic	0.884
MEN1	O00255-1.4	T56S	Neutral	0.093
MEN1	O00255-1.4	T56V	Neutral	0.15
MEN1	O00255-1.4	T56W	Pathogenic	0.988
MEN1	O00255-1.4	T56Y	Pathogenic	0.659
MEN1	O00255-1.4	N57A	Pathogenic	0.932
MEN1	O00255-1.4	N57C	Pathogenic	0.913
MEN1	O00255-1.4	N57D	Neutral	0.363
MEN1	O00255-1.4	N57E	Neutral	0.471
MEN1	O00255-1.4	N57F	Pathogenic	0.997
MEN1	O00255-1.4	N57G	Pathogenic	0.968
MEN1	O00255-1.4	N57H	Pathogenic	0.835
MEN1	O00255-1.4	N57I	Pathogenic	0.993
MEN1	O00255-1.4	N57K	Pathogenic	0.916
MEN1	O00255-1.4	N57L	Pathogenic	0.992
MEN1	O00255-1.4	N57M	Pathogenic	0.983
MEN1	O00255-1.4	N57P	Pathogenic	0.827
MEN1	O00255-1.4	N57Q	Pathogenic	0.693
MEN1	O00255-1.4	N57R	Pathogenic	0.967
MEN1	O00255-1.4	N57S	Pathogenic	0.806
MEN1	O00255-1.4	N57T	Pathogenic	0.615
MEN1	O00255-1.4	N57V	Pathogenic	0.934
MEN1	O00255-1.4	N57W	Pathogenic	1.0
MEN1	O00255-1.4	N57Y	Pathogenic	0.992
MEN1	O00255-1.4	V58A	Pathogenic	0.733
MEN1	O00255-1.4	V58C	Neutral	0.191
MEN1	O00255-1.4	V58D	Pathogenic	0.759
MEN1	O00255-1.4	V58E	Pathogenic	0.531
MEN1	O00255-1.4	V58F	Neutral	0.481
MEN1	O00255-1.4	V58G	Pathogenic	0.957
MEN1	O00255-1.4	V58H	Neutral	0.403
MEN1	O00255-1.4	V58I	Neutral	0.247
MEN1	O00255-1.4	V58K	Pathogenic	0.933
MEN1	O00255-1.4	V58L	Neutral	0.239
MEN1	O00255-1.4	V58M	Neutral	0.128
MEN1	O00255-1.4	V58N	Pathogenic	0.622
MEN1	O00255-1.4	V58P	Neutral	0.222
MEN1	O00255-1.4	V58Q	Neutral	0.455
MEN1	O00255-1.4	V58R	Pathogenic	0.976
MEN1	O00255-1.4	V58S	Pathogenic	0.776
MEN1	O00255-1.4	V58T	Neutral	0.299
MEN1	O00255-1.4	V58W	Pathogenic	0.947
MEN1	O00255-1.4	V58Y	Neutral	0.465
MEN1	O00255-1.4	P59A	Neutral	0.067
MEN1	O00255-1.4	P59C	Neutral	0.015
MEN1	O00255-1.4	P59D	Neutral	0.074
MEN1	O00255-1.4	P59E	Neutral	0.199
MEN1	O00255-1.4	P59F	Pathogenic	0.566
MEN1	O00255-1.4	P59G	Neutral	0.343
MEN1	O00255-1.4	P59H	Neutral	0.129
MEN1	O00255-1.4	P59I	Neutral	0.356
MEN1	O00255-1.4	P59K	Pathogenic	0.754
MEN1	O00255-1.4	P59L	Neutral	0.319
MEN1	O00255-1.4	P59M	Neutral	0.171
MEN1	O00255-1.4	P59N	Neutral	0.086
MEN1	O00255-1.4	P59Q	Neutral	0.155
MEN1	O00255-1.4	P59R	Pathogenic	0.898
MEN1	O00255-1.4	P59S	Neutral	0.075
MEN1	O00255-1.4	P59T	Neutral	0.017
MEN1	O00255-1.4	P59V	Neutral	0.046
MEN1	O00255-1.4	P59W	Pathogenic	0.957
MEN1	O00255-1.4	P59Y	Neutral	0.334
MEN1	O00255-1.4	E60A	Neutral	0.18
MEN1	O00255-1.4	E60C	Neutral	0.16
MEN1	O00255-1.4	E60D	Neutral	0.008
MEN1	O00255-1.4	E60F	Neutral	0.453
MEN1	O00255-1.4	E60G	Neutral	0.369
MEN1	O00255-1.4	E60H	Neutral	0.013
MEN1	O00255-1.4	E60I	Neutral	0.271
MEN1	O00255-1.4	E60K	Neutral	0.022
MEN1	O00255-1.4	E60L	Neutral	0.24
MEN1	O00255-1.4	E60M	Neutral	0.122
MEN1	O00255-1.4	E60N	Neutral	0.005
MEN1	O00255-1.4	E60P	Neutral	0.071
MEN1	O00255-1.4	E60Q	Neutral	0.005
MEN1	O00255-1.4	E60R	Neutral	0.061
MEN1	O00255-1.4	E60S	Neutral	0.07
MEN1	O00255-1.4	E60T	Neutral	0.028
MEN1	O00255-1.4	E60V	Neutral	0.056
MEN1	O00255-1.4	E60W	Pathogenic	0.934
MEN1	O00255-1.4	E60Y	Neutral	0.241
MEN1	O00255-1.4	L61A	Pathogenic	0.533
MEN1	O00255-1.4	L61C	Neutral	0.085
MEN1	O00255-1.4	L61D	Pathogenic	0.567
MEN1	O00255-1.4	L61E	Neutral	0.206
MEN1	O00255-1.4	L61F	Neutral	0.004
MEN1	O00255-1.4	L61G	Pathogenic	0.903
MEN1	O00255-1.4	L61H	Neutral	0.037
MEN1	O00255-1.4	L61I	Neutral	0.002
MEN1	O00255-1.4	L61K	Neutral	0.243
MEN1	O00255-1.4	L61M	Neutral	0.003
MEN1	O00255-1.4	L61N	Neutral	0.392
MEN1	O00255-1.4	L61P	Neutral	0.106
MEN1	O00255-1.4	L61Q	Neutral	0.079
MEN1	O00255-1.4	L61R	Neutral	0.465
MEN1	O00255-1.4	L61S	Pathogenic	0.576
MEN1	O00255-1.4	L61T	Neutral	0.151
MEN1	O00255-1.4	L61V	Neutral	0.013
MEN1	O00255-1.4	L61W	Neutral	0.075
MEN1	O00255-1.4	L61Y	Neutral	0.02
MEN1	O00255-1.4	T62A	Neutral	0.021
MEN1	O00255-1.4	T62C	Neutral	0.016
MEN1	O00255-1.4	T62D	Neutral	0.018
MEN1	O00255-1.4	T62E	Neutral	0.041
MEN1	O00255-1.4	T62F	Neutral	0.47
MEN1	O00255-1.4	T62G	Neutral	0.123
MEN1	O00255-1.4	T62H	Neutral	0.025
MEN1	O00255-1.4	T62I	Neutral	0.273
MEN1	O00255-1.4	T62K	Neutral	0.344
MEN1	O00255-1.4	T62L	Neutral	0.242
MEN1	O00255-1.4	T62M	Neutral	0.13
MEN1	O00255-1.4	T62N	Neutral	0.014
MEN1	O00255-1.4	T62P	Neutral	0.008
MEN1	O00255-1.4	T62Q	Neutral	0.03
MEN1	O00255-1.4	T62R	Pathogenic	0.587
MEN1	O00255-1.4	T62S	Neutral	0.019
MEN1	O00255-1.4	T62V	Neutral	0.032
MEN1	O00255-1.4	T62W	Pathogenic	0.938
MEN1	O00255-1.4	T62Y	Neutral	0.266
MEN1	O00255-1.4	F63A	Pathogenic	0.995
MEN1	O00255-1.4	F63C	Pathogenic	0.946
MEN1	O00255-1.4	F63D	Pathogenic	0.995
MEN1	O00255-1.4	F63E	Pathogenic	0.979
MEN1	O00255-1.4	F63G	Pathogenic	0.999
MEN1	O00255-1.4	F63H	Pathogenic	0.857
MEN1	O00255-1.4	F63I	Neutral	0.201
MEN1	O00255-1.4	F63K	Pathogenic	0.922
MEN1	O00255-1.4	F63L	Neutral	0.221
MEN1	O00255-1.4	F63M	Neutral	0.378
MEN1	O00255-1.4	F63N	Pathogenic	0.991
MEN1	O00255-1.4	F63P	Pathogenic	0.957
MEN1	O00255-1.4	F63Q	Pathogenic	0.942
MEN1	O00255-1.4	F63R	Pathogenic	0.97
MEN1	O00255-1.4	F63S	Pathogenic	0.996
MEN1	O00255-1.4	F63T	Pathogenic	0.971
MEN1	O00255-1.4	F63V	Pathogenic	0.732
MEN1	O00255-1.4	F63W	Pathogenic	0.636
MEN1	O00255-1.4	F63Y	Neutral	0.352
MEN1	O00255-1.4	Q64A	Neutral	0.269
MEN1	O00255-1.4	Q64C	Neutral	0.231
MEN1	O00255-1.4	Q64D	Neutral	0.057
MEN1	O00255-1.4	Q64E	Neutral	0.011
MEN1	O00255-1.4	Q64F	Neutral	0.397
MEN1	O00255-1.4	Q64G	Neutral	0.496
MEN1	O00255-1.4	Q64H	Neutral	0.01
MEN1	O00255-1.4	Q64I	Neutral	0.229
MEN1	O00255-1.4	Q64K	Neutral	0.065
MEN1	O00255-1.4	Q64L	Neutral	0.191
MEN1	O00255-1.4	Q64M	Neutral	0.089
MEN1	O00255-1.4	Q64N	Neutral	0.03
MEN1	O00255-1.4	Q64P	Neutral	0.114
MEN1	O00255-1.4	Q64R	Neutral	0.158
MEN1	O00255-1.4	Q64S	Neutral	0.113
MEN1	O00255-1.4	Q64T	Neutral	0.046
MEN1	O00255-1.4	Q64V	Neutral	0.091
MEN1	O00255-1.4	Q64W	Pathogenic	0.914
MEN1	O00255-1.4	Q64Y	Neutral	0.193
MEN1	O00255-1.4	P65A	Neutral	0.1
MEN1	O00255-1.4	P65C	Neutral	0.023
MEN1	O00255-1.4	P65D	Neutral	0.11
MEN1	O00255-1.4	P65E	Neutral	0.277
MEN1	O00255-1.4	P65F	Pathogenic	0.668
MEN1	O00255-1.4	P65G	Neutral	0.446
MEN1	O00255-1.4	P65H	Neutral	0.186
MEN1	O00255-1.4	P65I	Neutral	0.46
MEN1	O00255-1.4	P65K	Pathogenic	0.825
MEN1	O00255-1.4	P65L	Neutral	0.419
MEN1	O00255-1.4	P65M	Neutral	0.241
MEN1	O00255-1.4	P65N	Neutral	0.127
MEN1	O00255-1.4	P65Q	Neutral	0.22
MEN1	O00255-1.4	P65R	Pathogenic	0.931
MEN1	O00255-1.4	P65S	Neutral	0.111
MEN1	O00255-1.4	P65T	Neutral	0.026
MEN1	O00255-1.4	P65V	Neutral	0.07
MEN1	O00255-1.4	P65W	Pathogenic	0.972
MEN1	O00255-1.4	P65Y	Neutral	0.436
MEN1	O00255-1.4	S66A	Neutral	0.003
MEN1	O00255-1.4	S66C	Neutral	0.015
MEN1	O00255-1.4	S66D	Neutral	0.013
MEN1	O00255-1.4	S66E	Neutral	0.039
MEN1	O00255-1.4	S66F	Pathogenic	0.697
MEN1	O00255-1.4	S66G	Neutral	0.007
MEN1	O00255-1.4	S66H	Neutral	0.04
MEN1	O00255-1.4	S66I	Pathogenic	0.509
MEN1	O00255-1.4	S66K	Neutral	0.331
MEN1	O00255-1.4	S66L	Neutral	0.467
MEN1	O00255-1.4	S66M	Neutral	0.278
MEN1	O00255-1.4	S66N	Neutral	0.013
MEN1	O00255-1.4	S66P	Neutral	0.013
MEN1	O00255-1.4	S66Q	Neutral	0.029
MEN1	O00255-1.4	S66R	Pathogenic	0.587
MEN1	O00255-1.4	S66T	Neutral	0.007
MEN1	O00255-1.4	S66V	Neutral	0.088
MEN1	O00255-1.4	S66W	Pathogenic	0.977
MEN1	O00255-1.4	S66Y	Neutral	0.484
MEN1	O00255-1.4	P67A	Neutral	0.02
MEN1	O00255-1.4	P67C	Neutral	0.004
MEN1	O00255-1.4	P67D	Neutral	0.022
MEN1	O00255-1.4	P67E	Neutral	0.065
MEN1	O00255-1.4	P67F	Neutral	0.269
MEN1	O00255-1.4	P67G	Neutral	0.128
MEN1	O00255-1.4	P67H	Neutral	0.04
MEN1	O00255-1.4	P67I	Neutral	0.135
MEN1	O00255-1.4	P67K	Neutral	0.463
MEN1	O00255-1.4	P67L	Neutral	0.116
MEN1	O00255-1.4	P67M	Neutral	0.055
MEN1	O00255-1.4	P67N	Neutral	0.026
MEN1	O00255-1.4	P67Q	Neutral	0.049
MEN1	O00255-1.4	P67R	Pathogenic	0.712
MEN1	O00255-1.4	P67S	Neutral	0.022
MEN1	O00255-1.4	P67T	Neutral	0.005
MEN1	O00255-1.4	P67V	Neutral	0.014
MEN1	O00255-1.4	P67W	Pathogenic	0.863
MEN1	O00255-1.4	P67Y	Neutral	0.124
MEN1	O00255-1.4	A68C	Neutral	0.009
MEN1	O00255-1.4	A68D	Neutral	0.027
MEN1	O00255-1.4	A68E	Neutral	0.076
MEN1	O00255-1.4	A68F	Pathogenic	0.59
MEN1	O00255-1.4	A68G	Neutral	0.005
MEN1	O00255-1.4	A68H	Neutral	0.047
MEN1	O00255-1.4	A68I	Neutral	0.379
MEN1	O00255-1.4	A68K	Pathogenic	0.502
MEN1	O00255-1.4	A68L	Neutral	0.341
MEN1	O00255-1.4	A68M	Neutral	0.195
MEN1	O00255-1.4	A68N	Neutral	0.03
MEN1	O00255-1.4	A68P	Neutral	0.008
MEN1	O00255-1.4	A68Q	Neutral	0.057
MEN1	O00255-1.4	A68R	Pathogenic	0.732
MEN1	O00255-1.4	A68S	Neutral	0.002
MEN1	O00255-1.4	A68T	Neutral	0.005
MEN1	O00255-1.4	A68V	Neutral	0.051
MEN1	O00255-1.4	A68W	Pathogenic	0.963
MEN1	O00255-1.4	A68Y	Neutral	0.371
MEN1	O00255-1.4	P69A	Neutral	0.041
MEN1	O00255-1.4	P69C	Neutral	0.009
MEN1	O00255-1.4	P69D	Neutral	0.045
MEN1	O00255-1.4	P69E	Neutral	0.128
MEN1	O00255-1.4	P69F	Neutral	0.436
MEN1	O00255-1.4	P69G	Neutral	0.236
MEN1	O00255-1.4	P69H	Neutral	0.081
MEN1	O00255-1.4	P69I	Neutral	0.246
MEN1	O00255-1.4	P69K	Pathogenic	0.644
MEN1	O00255-1.4	P69L	Neutral	0.217
MEN1	O00255-1.4	P69M	Neutral	0.109
MEN1	O00255-1.4	P69N	Neutral	0.053
MEN1	O00255-1.4	P69Q	Neutral	0.098
MEN1	O00255-1.4	P69R	Pathogenic	0.839
MEN1	O00255-1.4	P69S	Neutral	0.046
MEN1	O00255-1.4	P69T	Neutral	0.01
MEN1	O00255-1.4	P69V	Neutral	0.028
MEN1	O00255-1.4	P69W	Pathogenic	0.93
MEN1	O00255-1.4	P69Y	Neutral	0.229
MEN1	O00255-1.4	D70A	Pathogenic	0.503
MEN1	O00255-1.4	D70C	Neutral	0.437
MEN1	O00255-1.4	D70E	Neutral	0.099
MEN1	O00255-1.4	D70F	Pathogenic	0.981
MEN1	O00255-1.4	D70G	Pathogenic	0.705
MEN1	O00255-1.4	D70H	Neutral	0.472
MEN1	O00255-1.4	D70I	Pathogenic	0.96
MEN1	O00255-1.4	D70K	Pathogenic	0.513
MEN1	O00255-1.4	D70L	Pathogenic	0.955
MEN1	O00255-1.4	D70M	Pathogenic	0.904
MEN1	O00255-1.4	D70N	Neutral	0.045
MEN1	O00255-1.4	D70P	Neutral	0.25
MEN1	O00255-1.4	D70Q	Neutral	0.261
MEN1	O00255-1.4	D70R	Pathogenic	0.752
MEN1	O00255-1.4	D70S	Neutral	0.247
MEN1	O00255-1.4	D70T	Neutral	0.145
MEN1	O00255-1.4	D70V	Pathogenic	0.69
MEN1	O00255-1.4	D70W	Pathogenic	0.999
MEN1	O00255-1.4	D70Y	Pathogenic	0.956
MEN1	O00255-1.4	P71A	Neutral	0.022
MEN1	O00255-1.4	P71C	Neutral	0.005
MEN1	O00255-1.4	P71D	Neutral	0.025
MEN1	O00255-1.4	P71E	Neutral	0.072
MEN1	O00255-1.4	P71F	Neutral	0.291
MEN1	O00255-1.4	P71G	Neutral	0.141
MEN1	O00255-1.4	P71H	Neutral	0.044
MEN1	O00255-1.4	P71I	Neutral	0.148
MEN1	O00255-1.4	P71K	Neutral	0.49
MEN1	O00255-1.4	P71L	Neutral	0.128
MEN1	O00255-1.4	P71M	Neutral	0.061
MEN1	O00255-1.4	P71N	Neutral	0.029
MEN1	O00255-1.4	P71Q	Neutral	0.054
MEN1	O00255-1.4	P71R	Pathogenic	0.734
MEN1	O00255-1.4	P71S	Neutral	0.025
MEN1	O00255-1.4	P71T	Neutral	0.006
MEN1	O00255-1.4	P71V	Neutral	0.015
MEN1	O00255-1.4	P71W	Pathogenic	0.875
MEN1	O00255-1.4	P71Y	Neutral	0.136
MEN1	O00255-1.4	P72A	Neutral	0.048
MEN1	O00255-1.4	P72C	Neutral	0.011
MEN1	O00255-1.4	P72D	Neutral	0.053
MEN1	O00255-1.4	P72E	Neutral	0.147
MEN1	O00255-1.4	P72F	Neutral	0.475
MEN1	O00255-1.4	P72G	Neutral	0.266
MEN1	O00255-1.4	P72H	Neutral	0.093
MEN1	O00255-1.4	P72I	Neutral	0.278
MEN1	O00255-1.4	P72K	Pathogenic	0.68
MEN1	O00255-1.4	P72L	Neutral	0.245
MEN1	O00255-1.4	P72M	Neutral	0.125
MEN1	O00255-1.4	P72N	Neutral	0.061
MEN1	O00255-1.4	P72Q	Neutral	0.113
MEN1	O00255-1.4	P72R	Pathogenic	0.859
MEN1	O00255-1.4	P72S	Neutral	0.053
MEN1	O00255-1.4	P72T	Neutral	0.012
MEN1	O00255-1.4	P72V	Neutral	0.033
MEN1	O00255-1.4	P72W	Pathogenic	0.939
MEN1	O00255-1.4	P72Y	Neutral	0.258
MEN1	O00255-1.4	G73A	Neutral	0.012
MEN1	O00255-1.4	G73C	Neutral	0.149
MEN1	O00255-1.4	G73D	Neutral	0.137
MEN1	O00255-1.4	G73E	Neutral	0.344
MEN1	O00255-1.4	G73F	Pathogenic	0.962
MEN1	O00255-1.4	G73H	Neutral	0.311
MEN1	O00255-1.4	G73I	Pathogenic	0.923
MEN1	O00255-1.4	G73K	Pathogenic	0.866
MEN1	O00255-1.4	G73L	Pathogenic	0.91
MEN1	O00255-1.4	G73M	Pathogenic	0.817
MEN1	O00255-1.4	G73N	Neutral	0.142
MEN1	O00255-1.4	G73P	Neutral	0.126
MEN1	O00255-1.4	G73Q	Neutral	0.278
MEN1	O00255-1.4	G73R	Pathogenic	0.946
MEN1	O00255-1.4	G73S	Neutral	0.012
MEN1	O00255-1.4	G73T	Neutral	0.079
MEN1	O00255-1.4	G73V	Pathogenic	0.513
MEN1	O00255-1.4	G73W	Pathogenic	0.998
MEN1	O00255-1.4	G73Y	Pathogenic	0.911
MEN1	O00255-1.4	G74A	Neutral	0.036
MEN1	O00255-1.4	G74C	Neutral	0.358
MEN1	O00255-1.4	G74D	Neutral	0.337
MEN1	O00255-1.4	G74E	Pathogenic	0.626
MEN1	O00255-1.4	G74F	Pathogenic	0.988
MEN1	O00255-1.4	G74H	Pathogenic	0.591
MEN1	O00255-1.4	G74I	Pathogenic	0.975
MEN1	O00255-1.4	G74K	Pathogenic	0.954
MEN1	O00255-1.4	G74L	Pathogenic	0.97
MEN1	O00255-1.4	G74M	Pathogenic	0.935
MEN1	O00255-1.4	G74N	Neutral	0.346
MEN1	O00255-1.4	G74P	Neutral	0.316
MEN1	O00255-1.4	G74Q	Pathogenic	0.552
MEN1	O00255-1.4	G74R	Pathogenic	0.982
MEN1	O00255-1.4	G74S	Neutral	0.037
MEN1	O00255-1.4	G74T	Neutral	0.214
MEN1	O00255-1.4	G74V	Pathogenic	0.771
MEN1	O00255-1.4	G74W	Pathogenic	0.999
MEN1	O00255-1.4	G74Y	Pathogenic	0.97
MEN1	O00255-1.4	L75A	Neutral	0.223
MEN1	O00255-1.4	L75C	Neutral	0.023
MEN1	O00255-1.4	L75D	Neutral	0.248
MEN1	O00255-1.4	L75E	Neutral	0.061
MEN1	O00255-1.4	L75F	Neutral	0.001
MEN1	O00255-1.4	L75G	Pathogenic	0.701
MEN1	O00255-1.4	L75H	Neutral	0.009
MEN1	O00255-1.4	L75I	Neutral	0.0
MEN1	O00255-1.4	L75K	Neutral	0.075
MEN1	O00255-1.4	L75M	Neutral	0.001
MEN1	O00255-1.4	L75N	Neutral	0.14
MEN1	O00255-1.4	L75P	Neutral	0.029
MEN1	O00255-1.4	L75Q	Neutral	0.021
MEN1	O00255-1.4	L75R	Neutral	0.179
MEN1	O00255-1.4	L75S	Neutral	0.254
MEN1	O00255-1.4	L75T	Neutral	0.043
MEN1	O00255-1.4	L75V	Neutral	0.003
MEN1	O00255-1.4	L75W	Neutral	0.02
MEN1	O00255-1.4	L75Y	Neutral	0.005
MEN1	O00255-1.4	T76A	Neutral	0.058
MEN1	O00255-1.4	T76C	Neutral	0.045
MEN1	O00255-1.4	T76D	Neutral	0.051
MEN1	O00255-1.4	T76E	Neutral	0.109
MEN1	O00255-1.4	T76F	Pathogenic	0.718
MEN1	O00255-1.4	T76G	Neutral	0.287
MEN1	O00255-1.4	T76H	Neutral	0.068
MEN1	O00255-1.4	T76I	Pathogenic	0.519
MEN1	O00255-1.4	T76K	Pathogenic	0.601
MEN1	O00255-1.4	T76L	Neutral	0.478
MEN1	O00255-1.4	T76M	Neutral	0.299
MEN1	O00255-1.4	T76N	Neutral	0.039
MEN1	O00255-1.4	T76P	Neutral	0.022
MEN1	O00255-1.4	T76Q	Neutral	0.083
MEN1	O00255-1.4	T76R	Pathogenic	0.803
MEN1	O00255-1.4	T76S	Neutral	0.052
MEN1	O00255-1.4	T76V	Neutral	0.087
MEN1	O00255-1.4	T76W	Pathogenic	0.978
MEN1	O00255-1.4	T76Y	Pathogenic	0.51
MEN1	O00255-1.4	Y77A	Pathogenic	0.874
MEN1	O00255-1.4	Y77C	Neutral	0.375
MEN1	O00255-1.4	Y77D	Pathogenic	0.875
MEN1	O00255-1.4	Y77E	Pathogenic	0.582
MEN1	O00255-1.4	Y77F	Neutral	0.041
MEN1	O00255-1.4	Y77G	Pathogenic	0.98
MEN1	O00255-1.4	Y77H	Neutral	0.138
MEN1	O00255-1.4	Y77I	Neutral	0.112
MEN1	O00255-1.4	Y77K	Neutral	0.261
MEN1	O00255-1.4	Y77L	Neutral	0.096
MEN1	O00255-1.4	Y77M	Neutral	0.047
MEN1	O00255-1.4	Y77N	Pathogenic	0.776
MEN1	O00255-1.4	Y77P	Neutral	0.404
MEN1	O00255-1.4	Y77Q	Neutral	0.314
MEN1	O00255-1.4	Y77R	Neutral	0.28
MEN1	O00255-1.4	Y77S	Pathogenic	0.885
MEN1	O00255-1.4	Y77T	Pathogenic	0.519
MEN1	O00255-1.4	Y77V	Neutral	0.167
MEN1	O00255-1.4	Y77W	Neutral	0.239
MEN1	O00255-1.4	F78A	Pathogenic	1.0
MEN1	O00255-1.4	F78C	Pathogenic	0.995
MEN1	O00255-1.4	F78D	Pathogenic	1.0
MEN1	O00255-1.4	F78E	Pathogenic	0.998
MEN1	O00255-1.4	F78G	Pathogenic	1.0
MEN1	O00255-1.4	F78H	Pathogenic	0.986
MEN1	O00255-1.4	F78I	Pathogenic	0.749
MEN1	O00255-1.4	F78K	Pathogenic	0.993
MEN1	O00255-1.4	F78L	Pathogenic	0.77
MEN1	O00255-1.4	F78M	Pathogenic	0.878
MEN1	O00255-1.4	F78N	Pathogenic	0.999
MEN1	O00255-1.4	F78P	Pathogenic	0.996
MEN1	O00255-1.4	F78Q	Pathogenic	0.995
MEN1	O00255-1.4	F78R	Pathogenic	0.997
MEN1	O00255-1.4	F78S	Pathogenic	1.0
MEN1	O00255-1.4	F78T	Pathogenic	0.998
MEN1	O00255-1.4	F78V	Pathogenic	0.97
MEN1	O00255-1.4	F78W	Pathogenic	0.954
MEN1	O00255-1.4	F78Y	Pathogenic	0.865
MEN1	O00255-1.4	P79A	Pathogenic	0.955
MEN1	O00255-1.4	P79C	Pathogenic	0.819
MEN1	O00255-1.4	P79D	Pathogenic	0.959
MEN1	O00255-1.4	P79E	Pathogenic	0.986
MEN1	O00255-1.4	P79F	Pathogenic	0.997
MEN1	O00255-1.4	P79G	Pathogenic	0.993
MEN1	O00255-1.4	P79H	Pathogenic	0.977
MEN1	O00255-1.4	P79I	Pathogenic	0.994
MEN1	O00255-1.4	P79K	Pathogenic	0.999
MEN1	O00255-1.4	P79L	Pathogenic	0.993
MEN1	O00255-1.4	P79M	Pathogenic	0.984
MEN1	O00255-1.4	P79N	Pathogenic	0.965
MEN1	O00255-1.4	P79Q	Pathogenic	0.982
MEN1	O00255-1.4	P79R	Pathogenic	1.0
MEN1	O00255-1.4	P79S	Pathogenic	0.959
MEN1	O00255-1.4	P79T	Pathogenic	0.837
MEN1	O00255-1.4	P79V	Pathogenic	0.934
MEN1	O00255-1.4	P79W	Pathogenic	1.0
MEN1	O00255-1.4	P79Y	Pathogenic	0.993
MEN1	O00255-1.4	V80A	Neutral	0.28
MEN1	O00255-1.4	V80C	Neutral	0.032
MEN1	O00255-1.4	V80D	Neutral	0.308
MEN1	O00255-1.4	V80E	Neutral	0.138
MEN1	O00255-1.4	V80F	Neutral	0.116
MEN1	O00255-1.4	V80G	Pathogenic	0.76
MEN1	O00255-1.4	V80H	Neutral	0.087
MEN1	O00255-1.4	V80I	Neutral	0.044
MEN1	O00255-1.4	V80K	Pathogenic	0.664
MEN1	O00255-1.4	V80L	Neutral	0.043
MEN1	O00255-1.4	V80M	Neutral	0.02
MEN1	O00255-1.4	V80N	Neutral	0.189
MEN1	O00255-1.4	V80P	Neutral	0.039
MEN1	O00255-1.4	V80Q	Neutral	0.106
MEN1	O00255-1.4	V80R	Pathogenic	0.85
MEN1	O00255-1.4	V80S	Neutral	0.329
MEN1	O00255-1.4	V80T	Neutral	0.057
MEN1	O00255-1.4	V80W	Pathogenic	0.717
MEN1	O00255-1.4	V80Y	Neutral	0.11
MEN1	O00255-1.4	A81C	Neutral	0.035
MEN1	O00255-1.4	A81D	Neutral	0.102
MEN1	O00255-1.4	A81E	Neutral	0.249
MEN1	O00255-1.4	A81F	Pathogenic	0.854
MEN1	O00255-1.4	A81G	Neutral	0.02
MEN1	O00255-1.4	A81H	Neutral	0.165
MEN1	O00255-1.4	A81I	Pathogenic	0.713
MEN1	O00255-1.4	A81K	Pathogenic	0.803
MEN1	O00255-1.4	A81L	Pathogenic	0.677
MEN1	O00255-1.4	A81M	Neutral	0.495
MEN1	O00255-1.4	A81N	Neutral	0.112
MEN1	O00255-1.4	A81P	Neutral	0.033
MEN1	O00255-1.4	A81Q	Neutral	0.196
MEN1	O00255-1.4	A81R	Pathogenic	0.917
MEN1	O00255-1.4	A81S	Neutral	0.007
MEN1	O00255-1.4	A81T	Neutral	0.022
MEN1	O00255-1.4	A81V	Neutral	0.179
MEN1	O00255-1.4	A81W	Pathogenic	0.991
MEN1	O00255-1.4	A81Y	Pathogenic	0.705
MEN1	O00255-1.4	D82A	Neutral	0.43
MEN1	O00255-1.4	D82C	Neutral	0.367
MEN1	O00255-1.4	D82E	Neutral	0.076
MEN1	O00255-1.4	D82F	Pathogenic	0.975
MEN1	O00255-1.4	D82G	Pathogenic	0.641
MEN1	O00255-1.4	D82H	Neutral	0.401
MEN1	O00255-1.4	D82I	Pathogenic	0.947
MEN1	O00255-1.4	D82K	Neutral	0.441
MEN1	O00255-1.4	D82L	Pathogenic	0.941
MEN1	O00255-1.4	D82M	Pathogenic	0.875
MEN1	O00255-1.4	D82N	Neutral	0.034
MEN1	O00255-1.4	D82P	Neutral	0.199
MEN1	O00255-1.4	D82Q	Neutral	0.209
MEN1	O00255-1.4	D82R	Pathogenic	0.693
MEN1	O00255-1.4	D82S	Neutral	0.196
MEN1	O00255-1.4	D82T	Neutral	0.112
MEN1	O00255-1.4	D82V	Pathogenic	0.624
MEN1	O00255-1.4	D82W	Pathogenic	0.999
MEN1	O00255-1.4	D82Y	Pathogenic	0.942
MEN1	O00255-1.4	L83A	Pathogenic	0.932
MEN1	O00255-1.4	L83C	Pathogenic	0.524
MEN1	O00255-1.4	L83D	Pathogenic	0.94
MEN1	O00255-1.4	L83E	Pathogenic	0.756
MEN1	O00255-1.4	L83F	Neutral	0.047
MEN1	O00255-1.4	L83G	Pathogenic	0.991
MEN1	O00255-1.4	L83H	Neutral	0.312
MEN1	O00255-1.4	L83I	Neutral	0.019
MEN1	O00255-1.4	L83K	Pathogenic	0.793
MEN1	O00255-1.4	L83M	Neutral	0.035
MEN1	O00255-1.4	L83N	Pathogenic	0.885
MEN1	O00255-1.4	L83P	Pathogenic	0.586
MEN1	O00255-1.4	L83Q	Pathogenic	0.504
MEN1	O00255-1.4	L83R	Pathogenic	0.912
MEN1	O00255-1.4	L83S	Pathogenic	0.942
MEN1	O00255-1.4	L83T	Pathogenic	0.68
MEN1	O00255-1.4	L83V	Neutral	0.139
MEN1	O00255-1.4	L83W	Neutral	0.49
MEN1	O00255-1.4	L83Y	Neutral	0.192
MEN1	O00255-1.4	S84A	Neutral	0.005
MEN1	O00255-1.4	S84C	Neutral	0.029
MEN1	O00255-1.4	S84D	Neutral	0.025
MEN1	O00255-1.4	S84E	Neutral	0.072
MEN1	O00255-1.4	S84F	Pathogenic	0.817
MEN1	O00255-1.4	S84G	Neutral	0.014
MEN1	O00255-1.4	S84H	Neutral	0.075
MEN1	O00255-1.4	S84I	Pathogenic	0.669
MEN1	O00255-1.4	S84K	Neutral	0.491
MEN1	O00255-1.4	S84L	Pathogenic	0.631
MEN1	O00255-1.4	S84M	Neutral	0.429
MEN1	O00255-1.4	S84N	Neutral	0.026
MEN1	O00255-1.4	S84P	Neutral	0.025
MEN1	O00255-1.4	S84Q	Neutral	0.055
MEN1	O00255-1.4	S84R	Pathogenic	0.735
MEN1	O00255-1.4	S84T	Neutral	0.013
MEN1	O00255-1.4	S84V	Neutral	0.159
MEN1	O00255-1.4	S84W	Pathogenic	0.988
MEN1	O00255-1.4	S84Y	Pathogenic	0.646
MEN1	O00255-1.4	I85A	Pathogenic	0.911
MEN1	O00255-1.4	I85C	Neutral	0.455
MEN1	O00255-1.4	I85D	Pathogenic	0.917
MEN1	O00255-1.4	I85E	Pathogenic	0.7
MEN1	O00255-1.4	I85F	Neutral	0.027
MEN1	O00255-1.4	I85G	Pathogenic	0.988
MEN1	O00255-1.4	I85H	Neutral	0.255
MEN1	O00255-1.4	I85K	Pathogenic	0.754
MEN1	O00255-1.4	I85L	Neutral	0.013
MEN1	O00255-1.4	I85M	Neutral	0.028
MEN1	O00255-1.4	I85N	Pathogenic	0.853
MEN1	O00255-1.4	I85P	Pathogenic	0.517
MEN1	O00255-1.4	I85Q	Neutral	0.45
MEN1	O00255-1.4	I85R	Pathogenic	0.892
MEN1	O00255-1.4	I85S	Pathogenic	0.924
MEN1	O00255-1.4	I85T	Pathogenic	0.616
MEN1	O00255-1.4	I85V	Neutral	0.098
MEN1	O00255-1.4	I85W	Neutral	0.356
MEN1	O00255-1.4	I85Y	Neutral	0.153
MEN1	O00255-1.4	I86A	Pathogenic	0.987
MEN1	O00255-1.4	I86C	Pathogenic	0.858
MEN1	O00255-1.4	I86D	Pathogenic	0.988
MEN1	O00255-1.4	I86E	Pathogenic	0.944
MEN1	O00255-1.4	I86F	Neutral	0.17
MEN1	O00255-1.4	I86G	Pathogenic	0.998
MEN1	O00255-1.4	I86H	Pathogenic	0.713
MEN1	O00255-1.4	I86K	Pathogenic	0.957
MEN1	O00255-1.4	I86L	Neutral	0.084
MEN1	O00255-1.4	I86M	Neutral	0.173
MEN1	O00255-1.4	I86N	Pathogenic	0.977
MEN1	O00255-1.4	I86P	Pathogenic	0.886
MEN1	O00255-1.4	I86Q	Pathogenic	0.856
MEN1	O00255-1.4	I86R	Pathogenic	0.984
MEN1	O00255-1.4	I86S	Pathogenic	0.989
MEN1	O00255-1.4	I86T	Pathogenic	0.921
MEN1	O00255-1.4	I86V	Neutral	0.44
MEN1	O00255-1.4	I86W	Pathogenic	0.8
MEN1	O00255-1.4	I86Y	Pathogenic	0.567
MEN1	O00255-1.4	A87C	Neutral	0.008
MEN1	O00255-1.4	A87D	Neutral	0.024
MEN1	O00255-1.4	A87E	Neutral	0.067
MEN1	O00255-1.4	A87F	Pathogenic	0.56
MEN1	O00255-1.4	A87G	Neutral	0.004
MEN1	O00255-1.4	A87H	Neutral	0.041
MEN1	O00255-1.4	A87I	Neutral	0.351
MEN1	O00255-1.4	A87K	Neutral	0.471
MEN1	O00255-1.4	A87L	Neutral	0.314
MEN1	O00255-1.4	A87M	Neutral	0.176
MEN1	O00255-1.4	A87N	Neutral	0.027
MEN1	O00255-1.4	A87P	Neutral	0.007
MEN1	O00255-1.4	A87Q	Neutral	0.051
MEN1	O00255-1.4	A87R	Pathogenic	0.706
MEN1	O00255-1.4	A87S	Neutral	0.002
MEN1	O00255-1.4	A87T	Neutral	0.005
MEN1	O00255-1.4	A87V	Neutral	0.045
MEN1	O00255-1.4	A87W	Pathogenic	0.959
MEN1	O00255-1.4	A87Y	Neutral	0.342
MEN1	O00255-1.4	A88C	Pathogenic	0.823
MEN1	O00255-1.4	A88D	Pathogenic	0.936
MEN1	O00255-1.4	A88E	Pathogenic	0.977
MEN1	O00255-1.4	A88F	Pathogenic	0.999
MEN1	O00255-1.4	A88G	Pathogenic	0.72
MEN1	O00255-1.4	A88H	Pathogenic	0.962
MEN1	O00255-1.4	A88I	Pathogenic	0.997
MEN1	O00255-1.4	A88K	Pathogenic	0.998
MEN1	O00255-1.4	A88L	Pathogenic	0.996
MEN1	O00255-1.4	A88M	Pathogenic	0.992
MEN1	O00255-1.4	A88N	Pathogenic	0.942
MEN1	O00255-1.4	A88P	Pathogenic	0.813
MEN1	O00255-1.4	A88Q	Pathogenic	0.969
MEN1	O00255-1.4	A88R	Pathogenic	0.999
MEN1	O00255-1.4	A88S	Neutral	0.493
MEN1	O00255-1.4	A88T	Pathogenic	0.741
MEN1	O00255-1.4	A88V	Pathogenic	0.966
MEN1	O00255-1.4	A88W	Pathogenic	1.0
MEN1	O00255-1.4	A88Y	Pathogenic	0.997
MEN1	O00255-1.4	L89A	Pathogenic	0.998
MEN1	O00255-1.4	L89C	Pathogenic	0.979
MEN1	O00255-1.4	L89D	Pathogenic	0.999
MEN1	O00255-1.4	L89E	Pathogenic	0.993
MEN1	O00255-1.4	L89F	Pathogenic	0.682
MEN1	O00255-1.4	L89G	Pathogenic	1.0
MEN1	O00255-1.4	L89H	Pathogenic	0.951
MEN1	O00255-1.4	L89I	Neutral	0.462
MEN1	O00255-1.4	L89K	Pathogenic	0.994
MEN1	O00255-1.4	L89M	Pathogenic	0.608
MEN1	O00255-1.4	L89N	Pathogenic	0.997
MEN1	O00255-1.4	L89P	Pathogenic	0.984
MEN1	O00255-1.4	L89Q	Pathogenic	0.978
MEN1	O00255-1.4	L89R	Pathogenic	0.998
MEN1	O00255-1.4	L89S	Pathogenic	0.999
MEN1	O00255-1.4	L89T	Pathogenic	0.989
MEN1	O00255-1.4	L89V	Pathogenic	0.875
MEN1	O00255-1.4	L89W	Pathogenic	0.976
MEN1	O00255-1.4	L89Y	Pathogenic	0.911
MEN1	O00255-1.4	Y90A	Pathogenic	0.999
MEN1	O00255-1.4	Y90C	Pathogenic	0.988
MEN1	O00255-1.4	Y90D	Pathogenic	0.999
MEN1	O00255-1.4	Y90E	Pathogenic	0.995
MEN1	O00255-1.4	Y90F	Pathogenic	0.848
MEN1	O00255-1.4	Y90G	Pathogenic	1.0
MEN1	O00255-1.4	Y90H	Pathogenic	0.955
MEN1	O00255-1.4	Y90I	Pathogenic	0.943
MEN1	O00255-1.4	Y90K	Pathogenic	0.979
MEN1	O00255-1.4	Y90L	Pathogenic	0.933
MEN1	O00255-1.4	Y90M	Pathogenic	0.867
MEN1	O00255-1.4	Y90N	Pathogenic	0.998
MEN1	O00255-1.4	Y90P	Pathogenic	0.989
MEN1	O00255-1.4	Y90Q	Pathogenic	0.984
MEN1	O00255-1.4	Y90R	Pathogenic	0.981
MEN1	O00255-1.4	Y90S	Pathogenic	0.999
MEN1	O00255-1.4	Y90T	Pathogenic	0.993
MEN1	O00255-1.4	Y90V	Pathogenic	0.964
MEN1	O00255-1.4	Y90W	Pathogenic	0.976
MEN1	O00255-1.4	A91C	Neutral	0.011
MEN1	O00255-1.4	A91D	Neutral	0.034
MEN1	O00255-1.4	A91E	Neutral	0.094
MEN1	O00255-1.4	A91F	Pathogenic	0.647
MEN1	O00255-1.4	A91G	Neutral	0.006
MEN1	O00255-1.4	A91H	Neutral	0.058
MEN1	O00255-1.4	A91I	Neutral	0.438
MEN1	O00255-1.4	A91K	Pathogenic	0.562
MEN1	O00255-1.4	A91L	Neutral	0.397
MEN1	O00255-1.4	A91M	Neutral	0.235
MEN1	O00255-1.4	A91N	Neutral	0.038
MEN1	O00255-1.4	A91P	Neutral	0.01
MEN1	O00255-1.4	A91Q	Neutral	0.071
MEN1	O00255-1.4	A91R	Pathogenic	0.776
MEN1	O00255-1.4	A91S	Neutral	0.002
MEN1	O00255-1.4	A91T	Neutral	0.007
MEN1	O00255-1.4	A91V	Neutral	0.064
MEN1	O00255-1.4	A91W	Pathogenic	0.971
MEN1	O00255-1.4	A91Y	Neutral	0.428
MEN1	O00255-1.4	R92A	Pathogenic	0.999
MEN1	O00255-1.4	R92C	Pathogenic	0.998
MEN1	O00255-1.4	R92D	Pathogenic	0.961
MEN1	O00255-1.4	R92E	Pathogenic	0.877
MEN1	O00255-1.4	R92F	Pathogenic	0.984
MEN1	O00255-1.4	R92G	Pathogenic	1.0
MEN1	O00255-1.4	R92H	Pathogenic	0.927
MEN1	O00255-1.4	R92I	Pathogenic	0.993
MEN1	O00255-1.4	R92K	Neutral	0.339
MEN1	O00255-1.4	R92L	Pathogenic	0.991
MEN1	O00255-1.4	R92M	Pathogenic	0.981
MEN1	O00255-1.4	R92N	Pathogenic	0.952
MEN1	O00255-1.4	R92P	Pathogenic	0.997
MEN1	O00255-1.4	R92Q	Pathogenic	0.901
MEN1	O00255-1.4	R92S	Pathogenic	0.997
MEN1	O00255-1.4	R92T	Pathogenic	0.991
MEN1	O00255-1.4	R92V	Pathogenic	0.996
MEN1	O00255-1.4	R92W	Pathogenic	0.994
MEN1	O00255-1.4	R92Y	Pathogenic	0.908
MEN1	O00255-1.4	F93A	Pathogenic	1.0
MEN1	O00255-1.4	F93C	Pathogenic	0.999
MEN1	O00255-1.4	F93D	Pathogenic	1.0
MEN1	O00255-1.4	F93E	Pathogenic	1.0
MEN1	O00255-1.4	F93G	Pathogenic	1.0
MEN1	O00255-1.4	F93H	Pathogenic	0.998
MEN1	O00255-1.4	F93I	Pathogenic	0.961
MEN1	O00255-1.4	F93K	Pathogenic	0.999
MEN1	O00255-1.4	F93L	Pathogenic	0.965
MEN1	O00255-1.4	F93M	Pathogenic	0.984
MEN1	O00255-1.4	F93N	Pathogenic	1.0
MEN1	O00255-1.4	F93P	Pathogenic	1.0
MEN1	O00255-1.4	F93Q	Pathogenic	0.999
MEN1	O00255-1.4	F93R	Pathogenic	1.0
MEN1	O00255-1.4	F93S	Pathogenic	1.0
MEN1	O00255-1.4	F93T	Pathogenic	1.0
MEN1	O00255-1.4	F93V	Pathogenic	0.996
MEN1	O00255-1.4	F93W	Pathogenic	0.994
MEN1	O00255-1.4	F93Y	Pathogenic	0.982
MEN1	O00255-1.4	T94A	Neutral	0.139
MEN1	O00255-1.4	T94C	Neutral	0.11
MEN1	O00255-1.4	T94D	Neutral	0.122
MEN1	O00255-1.4	T94E	Neutral	0.242
MEN1	O00255-1.4	T94F	Pathogenic	0.869
MEN1	O00255-1.4	T94G	Pathogenic	0.512
MEN1	O00255-1.4	T94H	Neutral	0.16
MEN1	O00255-1.4	T94I	Pathogenic	0.738
MEN1	O00255-1.4	T94K	Pathogenic	0.797
MEN1	O00255-1.4	T94L	Pathogenic	0.704
MEN1	O00255-1.4	T94M	Pathogenic	0.527
MEN1	O00255-1.4	T94N	Neutral	0.097
MEN1	O00255-1.4	T94P	Neutral	0.056
MEN1	O00255-1.4	T94Q	Neutral	0.19
MEN1	O00255-1.4	T94R	Pathogenic	0.914
MEN1	O00255-1.4	T94S	Neutral	0.126
MEN1	O00255-1.4	T94V	Neutral	0.199
MEN1	O00255-1.4	T94W	Pathogenic	0.991
MEN1	O00255-1.4	T94Y	Pathogenic	0.731
MEN1	O00255-1.4	A95C	Pathogenic	0.574
MEN1	O00255-1.4	A95D	Pathogenic	0.81
MEN1	O00255-1.4	A95E	Pathogenic	0.925
MEN1	O00255-1.4	A95F	Pathogenic	0.995
MEN1	O00255-1.4	A95G	Neutral	0.427
MEN1	O00255-1.4	A95H	Pathogenic	0.881
MEN1	O00255-1.4	A95I	Pathogenic	0.989
MEN1	O00255-1.4	A95K	Pathogenic	0.994
MEN1	O00255-1.4	A95L	Pathogenic	0.987
MEN1	O00255-1.4	A95M	Pathogenic	0.973
MEN1	O00255-1.4	A95N	Pathogenic	0.824
MEN1	O00255-1.4	A95P	Pathogenic	0.557
MEN1	O00255-1.4	A95Q	Pathogenic	0.901
MEN1	O00255-1.4	A95R	Pathogenic	0.998
MEN1	O00255-1.4	A95S	Neutral	0.22
MEN1	O00255-1.4	A95T	Neutral	0.453
MEN1	O00255-1.4	A95V	Pathogenic	0.891
MEN1	O00255-1.4	A95W	Pathogenic	1.0
MEN1	O00255-1.4	A95Y	Pathogenic	0.989
MEN1	O00255-1.4	Q96A	Pathogenic	0.867
MEN1	O00255-1.4	Q96C	Pathogenic	0.841
MEN1	O00255-1.4	Q96D	Pathogenic	0.513
MEN1	O00255-1.4	Q96E	Neutral	0.164
MEN1	O00255-1.4	Q96F	Pathogenic	0.921
MEN1	O00255-1.4	Q96G	Pathogenic	0.945
MEN1	O00255-1.4	Q96H	Neutral	0.156
MEN1	O00255-1.4	Q96I	Pathogenic	0.839
MEN1	O00255-1.4	Q96K	Pathogenic	0.55
MEN1	O00255-1.4	Q96L	Pathogenic	0.806
MEN1	O00255-1.4	Q96M	Pathogenic	0.633
MEN1	O00255-1.4	Q96N	Neutral	0.356
MEN1	O00255-1.4	Q96P	Pathogenic	0.694
MEN1	O00255-1.4	Q96R	Pathogenic	0.768
MEN1	O00255-1.4	Q96S	Pathogenic	0.691
MEN1	O00255-1.4	Q96T	Neutral	0.461
MEN1	O00255-1.4	Q96V	Pathogenic	0.638
MEN1	O00255-1.4	Q96W	Pathogenic	0.995
MEN1	O00255-1.4	Q96Y	Pathogenic	0.808
MEN1	O00255-1.4	I97A	Pathogenic	0.998
MEN1	O00255-1.4	I97C	Pathogenic	0.976
MEN1	O00255-1.4	I97D	Pathogenic	0.998
MEN1	O00255-1.4	I97E	Pathogenic	0.991
MEN1	O00255-1.4	I97F	Pathogenic	0.578
MEN1	O00255-1.4	I97G	Pathogenic	1.0
MEN1	O00255-1.4	I97H	Pathogenic	0.943
MEN1	O00255-1.4	I97K	Pathogenic	0.993
MEN1	O00255-1.4	I97L	Neutral	0.381
MEN1	O00255-1.4	I97M	Pathogenic	0.583
MEN1	O00255-1.4	I97N	Pathogenic	0.996
MEN1	O00255-1.4	I97P	Pathogenic	0.981
MEN1	O00255-1.4	I97Q	Pathogenic	0.975
MEN1	O00255-1.4	I97R	Pathogenic	0.998
MEN1	O00255-1.4	I97S	Pathogenic	0.998
MEN1	O00255-1.4	I97T	Pathogenic	0.987
MEN1	O00255-1.4	I97V	Pathogenic	0.84
MEN1	O00255-1.4	I97W	Pathogenic	0.964
MEN1	O00255-1.4	I97Y	Pathogenic	0.897
MEN1	O00255-1.4	R98A	Pathogenic	0.996
MEN1	O00255-1.4	R98C	Pathogenic	0.995
MEN1	O00255-1.4	R98D	Pathogenic	0.883
MEN1	O00255-1.4	R98E	Pathogenic	0.684
MEN1	O00255-1.4	R98F	Pathogenic	0.95
MEN1	O00255-1.4	R98G	Pathogenic	0.998
MEN1	O00255-1.4	R98H	Pathogenic	0.794
MEN1	O00255-1.4	R98I	Pathogenic	0.978
MEN1	O00255-1.4	R98K	Neutral	0.135
MEN1	O00255-1.4	R98L	Pathogenic	0.973
MEN1	O00255-1.4	R98M	Pathogenic	0.94
MEN1	O00255-1.4	R98N	Pathogenic	0.859
MEN1	O00255-1.4	R98P	Pathogenic	0.989
MEN1	O00255-1.4	R98Q	Pathogenic	0.734
MEN1	O00255-1.4	R98S	Pathogenic	0.989
MEN1	O00255-1.4	R98T	Pathogenic	0.97
MEN1	O00255-1.4	R98V	Pathogenic	0.986
MEN1	O00255-1.4	R98W	Pathogenic	0.979
MEN1	O00255-1.4	R98Y	Pathogenic	0.749
MEN1	O00255-1.4	G99A	Pathogenic	0.663
MEN1	O00255-1.4	G99C	Pathogenic	0.967
MEN1	O00255-1.4	G99D	Pathogenic	0.964
MEN1	O00255-1.4	G99E	Pathogenic	0.989
MEN1	O00255-1.4	G99F	Pathogenic	1.0
MEN1	O00255-1.4	G99H	Pathogenic	0.987
MEN1	O00255-1.4	G99I	Pathogenic	1.0
MEN1	O00255-1.4	G99K	Pathogenic	0.999
MEN1	O00255-1.4	G99L	Pathogenic	0.999
MEN1	O00255-1.4	G99M	Pathogenic	0.999
MEN1	O00255-1.4	G99N	Pathogenic	0.965
MEN1	O00255-1.4	G99P	Pathogenic	0.96
MEN1	O00255-1.4	G99Q	Pathogenic	0.985
MEN1	O00255-1.4	G99R	Pathogenic	1.0
MEN1	O00255-1.4	G99S	Pathogenic	0.665
MEN1	O00255-1.4	G99T	Pathogenic	0.934
MEN1	O00255-1.4	G99V	Pathogenic	0.994
MEN1	O00255-1.4	G99W	Pathogenic	1.0
MEN1	O00255-1.4	G99Y	Pathogenic	0.999
MEN1	O00255-1.4	A100C	Neutral	0.167
MEN1	O00255-1.4	A100D	Neutral	0.386
MEN1	O00255-1.4	A100E	Pathogenic	0.647
MEN1	O00255-1.4	A100F	Pathogenic	0.97
MEN1	O00255-1.4	A100G	Neutral	0.099
MEN1	O00255-1.4	A100H	Pathogenic	0.523
MEN1	O00255-1.4	A100I	Pathogenic	0.932
MEN1	O00255-1.4	A100K	Pathogenic	0.958
MEN1	O00255-1.4	A100L	Pathogenic	0.921
MEN1	O00255-1.4	A100M	Pathogenic	0.844
MEN1	O00255-1.4	A100N	Neutral	0.41
MEN1	O00255-1.4	A100P	Neutral	0.157
MEN1	O00255-1.4	A100Q	Pathogenic	0.575
MEN1	O00255-1.4	A100R	Pathogenic	0.984
MEN1	O00255-1.4	A100S	Neutral	0.04
MEN1	O00255-1.4	A100T	Neutral	0.109
MEN1	O00255-1.4	A100V	Pathogenic	0.547
MEN1	O00255-1.4	A100W	Pathogenic	0.998
MEN1	O00255-1.4	A100Y	Pathogenic	0.93
MEN1	O00255-1.4	V101A	Pathogenic	0.963
MEN1	O00255-1.4	V101C	Pathogenic	0.689
MEN1	O00255-1.4	V101D	Pathogenic	0.967
MEN1	O00255-1.4	V101E	Pathogenic	0.914
MEN1	O00255-1.4	V101F	Pathogenic	0.897
MEN1	O00255-1.4	V101G	Pathogenic	0.995
MEN1	O00255-1.4	V101H	Pathogenic	0.864
MEN1	O00255-1.4	V101I	Pathogenic	0.755
MEN1	O00255-1.4	V101K	Pathogenic	0.992
MEN1	O00255-1.4	V101L	Pathogenic	0.746
MEN1	O00255-1.4	V101M	Pathogenic	0.579
MEN1	O00255-1.4	V101N	Pathogenic	0.939
MEN1	O00255-1.4	V101P	Pathogenic	0.728
MEN1	O00255-1.4	V101Q	Pathogenic	0.887
MEN1	O00255-1.4	V101R	Pathogenic	0.997
MEN1	O00255-1.4	V101S	Pathogenic	0.97
MEN1	O00255-1.4	V101T	Pathogenic	0.8
MEN1	O00255-1.4	V101W	Pathogenic	0.994
MEN1	O00255-1.4	V101Y	Pathogenic	0.891
MEN1	O00255-1.4	D102A	Pathogenic	0.98
MEN1	O00255-1.4	D102C	Pathogenic	0.974
MEN1	O00255-1.4	D102E	Pathogenic	0.842
MEN1	O00255-1.4	D102F	Pathogenic	1.0
MEN1	O00255-1.4	D102G	Pathogenic	0.991
MEN1	O00255-1.4	D102H	Pathogenic	0.978
MEN1	O00255-1.4	D102I	Pathogenic	0.999
MEN1	O00255-1.4	D102K	Pathogenic	0.981
MEN1	O00255-1.4	D102L	Pathogenic	0.999
MEN1	O00255-1.4	D102M	Pathogenic	0.998
MEN1	O00255-1.4	D102N	Pathogenic	0.695
MEN1	O00255-1.4	D102P	Pathogenic	0.942
MEN1	O00255-1.4	D102Q	Pathogenic	0.945
MEN1	O00255-1.4	D102R	Pathogenic	0.993
MEN1	O00255-1.4	D102S	Pathogenic	0.941
MEN1	O00255-1.4	D102T	Pathogenic	0.892
MEN1	O00255-1.4	D102V	Pathogenic	0.991
MEN1	O00255-1.4	D102W	Pathogenic	1.0
MEN1	O00255-1.4	D102Y	Pathogenic	0.999
MEN1	O00255-1.4	L103A	Pathogenic	0.989
MEN1	O00255-1.4	L103C	Pathogenic	0.878
MEN1	O00255-1.4	L103D	Pathogenic	0.99
MEN1	O00255-1.4	L103E	Pathogenic	0.953
MEN1	O00255-1.4	L103F	Neutral	0.246
MEN1	O00255-1.4	L103G	Pathogenic	0.999
MEN1	O00255-1.4	L103H	Pathogenic	0.748
MEN1	O00255-1.4	L103I	Neutral	0.115
MEN1	O00255-1.4	L103K	Pathogenic	0.962
MEN1	O00255-1.4	L103M	Neutral	0.191
MEN1	O00255-1.4	L103N	Pathogenic	0.981
MEN1	O00255-1.4	L103P	Pathogenic	0.903
MEN1	O00255-1.4	L103Q	Pathogenic	0.87
MEN1	O00255-1.4	L103R	Pathogenic	0.985
MEN1	O00255-1.4	L103S	Pathogenic	0.991
MEN1	O00255-1.4	L103T	Pathogenic	0.933
MEN1	O00255-1.4	L103V	Pathogenic	0.515
MEN1	O00255-1.4	L103W	Pathogenic	0.863
MEN1	O00255-1.4	L103Y	Pathogenic	0.61
MEN1	O00255-1.4	S104A	Neutral	0.157
MEN1	O00255-1.4	S104C	Pathogenic	0.515
MEN1	O00255-1.4	S104D	Neutral	0.477
MEN1	O00255-1.4	S104E	Pathogenic	0.739
MEN1	O00255-1.4	S104F	Pathogenic	0.994
MEN1	O00255-1.4	S104G	Neutral	0.332
MEN1	O00255-1.4	S104H	Pathogenic	0.744
MEN1	O00255-1.4	S104I	Pathogenic	0.986
MEN1	O00255-1.4	S104K	Pathogenic	0.972
MEN1	O00255-1.4	S104L	Pathogenic	0.984
MEN1	O00255-1.4	S104M	Pathogenic	0.964
MEN1	O00255-1.4	S104N	Neutral	0.487
MEN1	O00255-1.4	S104P	Neutral	0.482
MEN1	O00255-1.4	S104Q	Pathogenic	0.676
MEN1	O00255-1.4	S104R	Pathogenic	0.99
MEN1	O00255-1.4	S104T	Neutral	0.328
MEN1	O00255-1.4	S104V	Pathogenic	0.872
MEN1	O00255-1.4	S104W	Pathogenic	1.0
MEN1	O00255-1.4	S104Y	Pathogenic	0.985
MEN1	O00255-1.4	L105A	Neutral	0.415
MEN1	O00255-1.4	L105C	Neutral	0.054
MEN1	O00255-1.4	L105D	Neutral	0.448
MEN1	O00255-1.4	L105E	Neutral	0.139
MEN1	O00255-1.4	L105F	Neutral	0.003
MEN1	O00255-1.4	L105G	Pathogenic	0.853
MEN1	O00255-1.4	L105H	Neutral	0.023
MEN1	O00255-1.4	L105I	Neutral	0.001
MEN1	O00255-1.4	L105K	Neutral	0.166
MEN1	O00255-1.4	L105M	Neutral	0.002
MEN1	O00255-1.4	L105N	Neutral	0.286
MEN1	O00255-1.4	L105P	Neutral	0.069
MEN1	O00255-1.4	L105Q	Neutral	0.05
MEN1	O00255-1.4	L105R	Neutral	0.35
MEN1	O00255-1.4	L105S	Neutral	0.457
MEN1	O00255-1.4	L105T	Neutral	0.1
MEN1	O00255-1.4	L105V	Neutral	0.008
MEN1	O00255-1.4	L105W	Neutral	0.048
MEN1	O00255-1.4	L105Y	Neutral	0.012
MEN1	O00255-1.4	Y106A	Pathogenic	0.997
MEN1	O00255-1.4	Y106C	Pathogenic	0.971
MEN1	O00255-1.4	Y106D	Pathogenic	0.997
MEN1	O00255-1.4	Y106E	Pathogenic	0.987
MEN1	O00255-1.4	Y106F	Pathogenic	0.705
MEN1	O00255-1.4	Y106G	Pathogenic	1.0
MEN1	O00255-1.4	Y106H	Pathogenic	0.9
MEN1	O00255-1.4	Y106I	Pathogenic	0.876
MEN1	O00255-1.4	Y106K	Pathogenic	0.952
MEN1	O00255-1.4	Y106L	Pathogenic	0.857
MEN1	O00255-1.4	Y106M	Pathogenic	0.737
MEN1	O00255-1.4	Y106N	Pathogenic	0.995
MEN1	O00255-1.4	Y106P	Pathogenic	0.974
MEN1	O00255-1.4	Y106Q	Pathogenic	0.963
MEN1	O00255-1.4	Y106R	Pathogenic	0.956
MEN1	O00255-1.4	Y106S	Pathogenic	0.998
MEN1	O00255-1.4	Y106T	Pathogenic	0.984
MEN1	O00255-1.4	Y106V	Pathogenic	0.919
MEN1	O00255-1.4	Y106W	Pathogenic	0.947
MEN1	O00255-1.4	P107A	Neutral	0.031
MEN1	O00255-1.4	P107C	Neutral	0.007
MEN1	O00255-1.4	P107D	Neutral	0.035
MEN1	O00255-1.4	P107E	Neutral	0.1
MEN1	O00255-1.4	P107F	Neutral	0.368
MEN1	O00255-1.4	P107G	Neutral	0.189
MEN1	O00255-1.4	P107H	Neutral	0.062
MEN1	O00255-1.4	P107I	Neutral	0.198
MEN1	O00255-1.4	P107K	Pathogenic	0.578
MEN1	O00255-1.4	P107L	Neutral	0.173
MEN1	O00255-1.4	P107M	Neutral	0.084
MEN1	O00255-1.4	P107N	Neutral	0.04
MEN1	O00255-1.4	P107Q	Neutral	0.076
MEN1	O00255-1.4	P107R	Pathogenic	0.797
MEN1	O00255-1.4	P107S	Neutral	0.035
MEN1	O00255-1.4	P107T	Neutral	0.008
MEN1	O00255-1.4	P107V	Neutral	0.021
MEN1	O00255-1.4	P107W	Pathogenic	0.909
MEN1	O00255-1.4	P107Y	Neutral	0.183
MEN1	O00255-1.4	R108A	Pathogenic	0.991
MEN1	O00255-1.4	R108C	Pathogenic	0.989
MEN1	O00255-1.4	R108D	Pathogenic	0.781
MEN1	O00255-1.4	R108E	Pathogenic	0.505
MEN1	O00255-1.4	R108F	Pathogenic	0.9
MEN1	O00255-1.4	R108G	Pathogenic	0.997
MEN1	O00255-1.4	R108H	Pathogenic	0.645
MEN1	O00255-1.4	R108I	Pathogenic	0.954
MEN1	O00255-1.4	R108K	Neutral	0.068
MEN1	O00255-1.4	R108L	Pathogenic	0.943
MEN1	O00255-1.4	R108M	Pathogenic	0.88
MEN1	O00255-1.4	R108N	Pathogenic	0.741
MEN1	O00255-1.4	R108P	Pathogenic	0.977
MEN1	O00255-1.4	R108Q	Pathogenic	0.565
MEN1	O00255-1.4	R108S	Pathogenic	0.977
MEN1	O00255-1.4	R108T	Pathogenic	0.938
MEN1	O00255-1.4	R108V	Pathogenic	0.971
MEN1	O00255-1.4	R108W	Pathogenic	0.957
MEN1	O00255-1.4	R108Y	Pathogenic	0.585
MEN1	O00255-1.4	E109A	Neutral	0.035
MEN1	O00255-1.4	E109C	Neutral	0.031
MEN1	O00255-1.4	E109D	Neutral	0.001
MEN1	O00255-1.4	E109F	Neutral	0.121
MEN1	O00255-1.4	E109G	Neutral	0.088
MEN1	O00255-1.4	E109H	Neutral	0.002
MEN1	O00255-1.4	E109I	Neutral	0.058
MEN1	O00255-1.4	E109K	Neutral	0.004
MEN1	O00255-1.4	E109L	Neutral	0.05
MEN1	O00255-1.4	E109M	Neutral	0.023
MEN1	O00255-1.4	E109N	Neutral	0.001
MEN1	O00255-1.4	E109P	Neutral	0.013
MEN1	O00255-1.4	E109Q	Neutral	0.001
MEN1	O00255-1.4	E109R	Neutral	0.011
MEN1	O00255-1.4	E109S	Neutral	0.012
MEN1	O00255-1.4	E109T	Neutral	0.005
MEN1	O00255-1.4	E109V	Neutral	0.01
MEN1	O00255-1.4	E109W	Pathogenic	0.702
MEN1	O00255-1.4	E109Y	Neutral	0.05
MEN1	O00255-1.4	G110A	Neutral	0.012
MEN1	O00255-1.4	G110C	Neutral	0.15
MEN1	O00255-1.4	G110D	Neutral	0.139
MEN1	O00255-1.4	G110E	Neutral	0.347
MEN1	O00255-1.4	G110F	Pathogenic	0.962
MEN1	O00255-1.4	G110H	Neutral	0.314
MEN1	O00255-1.4	G110I	Pathogenic	0.924
MEN1	O00255-1.4	G110K	Pathogenic	0.867
MEN1	O00255-1.4	G110L	Pathogenic	0.911
MEN1	O00255-1.4	G110M	Pathogenic	0.819
MEN1	O00255-1.4	G110N	Neutral	0.144
MEN1	O00255-1.4	G110P	Neutral	0.128
MEN1	O00255-1.4	G110Q	Neutral	0.281
MEN1	O00255-1.4	G110R	Pathogenic	0.947
MEN1	O00255-1.4	G110S	Neutral	0.012
MEN1	O00255-1.4	G110T	Neutral	0.08
MEN1	O00255-1.4	G110V	Pathogenic	0.517
MEN1	O00255-1.4	G110W	Pathogenic	0.998
MEN1	O00255-1.4	G110Y	Pathogenic	0.912
MEN1	O00255-1.4	G111A	Neutral	0.023
MEN1	O00255-1.4	G111C	Neutral	0.262
MEN1	O00255-1.4	G111D	Neutral	0.244
MEN1	O00255-1.4	G111E	Pathogenic	0.515
MEN1	O00255-1.4	G111F	Pathogenic	0.981
MEN1	O00255-1.4	G111H	Neutral	0.478
MEN1	O00255-1.4	G111I	Pathogenic	0.961
MEN1	O00255-1.4	G111K	Pathogenic	0.929
MEN1	O00255-1.4	G111L	Pathogenic	0.954
MEN1	O00255-1.4	G111M	Pathogenic	0.901
MEN1	O00255-1.4	G111N	Neutral	0.252
MEN1	O00255-1.4	G111P	Neutral	0.227
MEN1	O00255-1.4	G111Q	Neutral	0.439
MEN1	O00255-1.4	G111R	Pathogenic	0.973
MEN1	O00255-1.4	G111S	Neutral	0.024
MEN1	O00255-1.4	G111T	Neutral	0.148
MEN1	O00255-1.4	G111V	Pathogenic	0.682
MEN1	O00255-1.4	G111W	Pathogenic	0.999
MEN1	O00255-1.4	G111Y	Pathogenic	0.954
MEN1	O00255-1.4	V112A	Neutral	0.085
MEN1	O00255-1.4	V112C	Neutral	0.008
MEN1	O00255-1.4	V112D	Neutral	0.097
MEN1	O00255-1.4	V112E	Neutral	0.037
MEN1	O00255-1.4	V112F	Neutral	0.031
MEN1	O00255-1.4	V112G	Neutral	0.432
MEN1	O00255-1.4	V112H	Neutral	0.022
MEN1	O00255-1.4	V112I	Neutral	0.011
MEN1	O00255-1.4	V112K	Neutral	0.322
MEN1	O00255-1.4	V112L	Neutral	0.011
MEN1	O00255-1.4	V112M	Neutral	0.005
MEN1	O00255-1.4	V112N	Neutral	0.053
MEN1	O00255-1.4	V112P	Neutral	0.01
MEN1	O00255-1.4	V112Q	Neutral	0.028
MEN1	O00255-1.4	V112R	Pathogenic	0.577
MEN1	O00255-1.4	V112S	Neutral	0.105
MEN1	O00255-1.4	V112T	Neutral	0.014
MEN1	O00255-1.4	V112W	Neutral	0.379
MEN1	O00255-1.4	V112Y	Neutral	0.029
MEN1	O00255-1.4	S113A	Neutral	0.142
MEN1	O00255-1.4	S113C	Neutral	0.484
MEN1	O00255-1.4	S113D	Neutral	0.446
MEN1	O00255-1.4	S113E	Pathogenic	0.714
MEN1	O00255-1.4	S113F	Pathogenic	0.993
MEN1	O00255-1.4	S113G	Neutral	0.305
MEN1	O00255-1.4	S113H	Pathogenic	0.72
MEN1	O00255-1.4	S113I	Pathogenic	0.985
MEN1	O00255-1.4	S113K	Pathogenic	0.969
MEN1	O00255-1.4	S113L	Pathogenic	0.982
MEN1	O00255-1.4	S113M	Pathogenic	0.96
MEN1	O00255-1.4	S113N	Neutral	0.456
MEN1	O00255-1.4	S113P	Neutral	0.452
MEN1	O00255-1.4	S113Q	Pathogenic	0.648
MEN1	O00255-1.4	S113R	Pathogenic	0.989
MEN1	O00255-1.4	S113T	Neutral	0.302
MEN1	O00255-1.4	S113V	Pathogenic	0.858
MEN1	O00255-1.4	S113W	Pathogenic	1.0
MEN1	O00255-1.4	S113Y	Pathogenic	0.983
MEN1	O00255-1.4	S114A	Neutral	0.085
MEN1	O00255-1.4	S114C	Neutral	0.347
MEN1	O00255-1.4	S114D	Neutral	0.313
MEN1	O00255-1.4	S114E	Pathogenic	0.586
MEN1	O00255-1.4	S114F	Pathogenic	0.988
MEN1	O00255-1.4	S114G	Neutral	0.199
MEN1	O00255-1.4	S114H	Pathogenic	0.593
MEN1	O00255-1.4	S114I	Pathogenic	0.973
MEN1	O00255-1.4	S114K	Pathogenic	0.946
MEN1	O00255-1.4	S114L	Pathogenic	0.969
MEN1	O00255-1.4	S114M	Pathogenic	0.931
MEN1	O00255-1.4	S114N	Neutral	0.322
MEN1	O00255-1.4	S114P	Neutral	0.318
MEN1	O00255-1.4	S114Q	Pathogenic	0.51
MEN1	O00255-1.4	S114R	Pathogenic	0.98
MEN1	O00255-1.4	S114T	Neutral	0.196
MEN1	O00255-1.4	S114V	Pathogenic	0.773
MEN1	O00255-1.4	S114W	Pathogenic	0.999
MEN1	O00255-1.4	S114Y	Pathogenic	0.971
MEN1	O00255-1.4	R115A	Pathogenic	1.0
MEN1	O00255-1.4	R115C	Pathogenic	1.0
MEN1	O00255-1.4	R115D	Pathogenic	0.997
MEN1	O00255-1.4	R115E	Pathogenic	0.991
MEN1	O00255-1.4	R115F	Pathogenic	0.999
MEN1	O00255-1.4	R115G	Pathogenic	1.0
MEN1	O00255-1.4	R115H	Pathogenic	0.995
MEN1	O00255-1.4	R115I	Pathogenic	1.0
MEN1	O00255-1.4	R115K	Pathogenic	0.885
MEN1	O00255-1.4	R115L	Pathogenic	0.999
MEN1	O00255-1.4	R115M	Pathogenic	0.999
MEN1	O00255-1.4	R115N	Pathogenic	0.997
MEN1	O00255-1.4	R115P	Pathogenic	1.0
MEN1	O00255-1.4	R115Q	Pathogenic	0.993
MEN1	O00255-1.4	R115S	Pathogenic	1.0
MEN1	O00255-1.4	R115T	Pathogenic	0.999
MEN1	O00255-1.4	R115V	Pathogenic	1.0
MEN1	O00255-1.4	R115W	Pathogenic	1.0
MEN1	O00255-1.4	R115Y	Pathogenic	0.993
MEN1	O00255-1.4	E116A	Pathogenic	0.981
MEN1	O00255-1.4	E116C	Pathogenic	0.978
MEN1	O00255-1.4	E116D	Pathogenic	0.66
MEN1	O00255-1.4	E116F	Pathogenic	0.995
MEN1	O00255-1.4	E116G	Pathogenic	0.993
MEN1	O00255-1.4	E116H	Pathogenic	0.759
MEN1	O00255-1.4	E116I	Pathogenic	0.989
MEN1	O00255-1.4	E116K	Pathogenic	0.843
MEN1	O00255-1.4	E116L	Pathogenic	0.987
MEN1	O00255-1.4	E116M	Pathogenic	0.971
MEN1	O00255-1.4	E116N	Pathogenic	0.564
MEN1	O00255-1.4	E116P	Pathogenic	0.948
MEN1	O00255-1.4	E116Q	Pathogenic	0.539
MEN1	O00255-1.4	E116R	Pathogenic	0.939
MEN1	O00255-1.4	E116S	Pathogenic	0.947
MEN1	O00255-1.4	E116T	Pathogenic	0.873
MEN1	O00255-1.4	E116V	Pathogenic	0.934
MEN1	O00255-1.4	E116W	Pathogenic	1.0
MEN1	O00255-1.4	E116Y	Pathogenic	0.987
MEN1	O00255-1.4	L117A	Pathogenic	0.994
MEN1	O00255-1.4	L117C	Pathogenic	0.934
MEN1	O00255-1.4	L117D	Pathogenic	0.995
MEN1	O00255-1.4	L117E	Pathogenic	0.975
MEN1	O00255-1.4	L117F	Neutral	0.39
MEN1	O00255-1.4	L117G	Pathogenic	0.999
MEN1	O00255-1.4	L117H	Pathogenic	0.853
MEN1	O00255-1.4	L117I	Neutral	0.203
MEN1	O00255-1.4	L117K	Pathogenic	0.98
MEN1	O00255-1.4	L117M	Neutral	0.316
MEN1	O00255-1.4	L117N	Pathogenic	0.99
MEN1	O00255-1.4	L117P	Pathogenic	0.948
MEN1	O00255-1.4	L117Q	Pathogenic	0.929
MEN1	O00255-1.4	L117R	Pathogenic	0.993
MEN1	O00255-1.4	L117S	Pathogenic	0.995
MEN1	O00255-1.4	L117T	Pathogenic	0.965
MEN1	O00255-1.4	L117V	Pathogenic	0.675
MEN1	O00255-1.4	L117W	Pathogenic	0.925
MEN1	O00255-1.4	L117Y	Pathogenic	0.754
MEN1	O00255-1.4	V118A	Pathogenic	0.968
MEN1	O00255-1.4	V118C	Pathogenic	0.72
MEN1	O00255-1.4	V118D	Pathogenic	0.972
MEN1	O00255-1.4	V118E	Pathogenic	0.925
MEN1	O00255-1.4	V118F	Pathogenic	0.91
MEN1	O00255-1.4	V118G	Pathogenic	0.996
MEN1	O00255-1.4	V118H	Pathogenic	0.88
MEN1	O00255-1.4	V118I	Pathogenic	0.781
MEN1	O00255-1.4	V118K	Pathogenic	0.993
MEN1	O00255-1.4	V118L	Pathogenic	0.773
MEN1	O00255-1.4	V118M	Pathogenic	0.614
MEN1	O00255-1.4	V118N	Pathogenic	0.947
MEN1	O00255-1.4	V118P	Pathogenic	0.756
MEN1	O00255-1.4	V118Q	Pathogenic	0.901
MEN1	O00255-1.4	V118R	Pathogenic	0.998
MEN1	O00255-1.4	V118S	Pathogenic	0.974
MEN1	O00255-1.4	V118T	Pathogenic	0.823
MEN1	O00255-1.4	V118W	Pathogenic	0.995
MEN1	O00255-1.4	V118Y	Pathogenic	0.905
MEN1	O00255-1.4	K119A	Pathogenic	1.0
MEN1	O00255-1.4	K119C	Pathogenic	0.999
MEN1	O00255-1.4	K119D	Pathogenic	0.986
MEN1	O00255-1.4	K119E	Pathogenic	0.952
MEN1	O00255-1.4	K119F	Pathogenic	0.995
MEN1	O00255-1.4	K119G	Pathogenic	1.0
MEN1	O00255-1.4	K119H	Pathogenic	0.976
MEN1	O00255-1.4	K119I	Pathogenic	0.998
MEN1	O00255-1.4	K119L	Pathogenic	0.997
MEN1	O00255-1.4	K119M	Pathogenic	0.993
MEN1	O00255-1.4	K119N	Pathogenic	0.983
MEN1	O00255-1.4	K119P	Pathogenic	0.999
MEN1	O00255-1.4	K119Q	Pathogenic	0.964
MEN1	O00255-1.4	K119R	Pathogenic	0.805
MEN1	O00255-1.4	K119S	Pathogenic	0.999
MEN1	O00255-1.4	K119T	Pathogenic	0.997
MEN1	O00255-1.4	K119V	Pathogenic	0.998
MEN1	O00255-1.4	K119W	Pathogenic	1.0
MEN1	O00255-1.4	K119Y	Pathogenic	0.986
MEN1	O00255-1.4	K120A	Pathogenic	0.999
MEN1	O00255-1.4	K120C	Pathogenic	0.999
MEN1	O00255-1.4	K120D	Pathogenic	0.96
MEN1	O00255-1.4	K120E	Pathogenic	0.873
MEN1	O00255-1.4	K120F	Pathogenic	0.985
MEN1	O00255-1.4	K120G	Pathogenic	1.0
MEN1	O00255-1.4	K120H	Pathogenic	0.932
MEN1	O00255-1.4	K120I	Pathogenic	0.993
MEN1	O00255-1.4	K120L	Pathogenic	0.992
MEN1	O00255-1.4	K120M	Pathogenic	0.981
MEN1	O00255-1.4	K120N	Pathogenic	0.953
MEN1	O00255-1.4	K120P	Pathogenic	0.997
MEN1	O00255-1.4	K120Q	Pathogenic	0.903
MEN1	O00255-1.4	K120R	Pathogenic	0.586
MEN1	O00255-1.4	K120S	Pathogenic	0.996
MEN1	O00255-1.4	K120T	Pathogenic	0.991
MEN1	O00255-1.4	K120V	Pathogenic	0.996
MEN1	O00255-1.4	K120W	Pathogenic	0.999
MEN1	O00255-1.4	K120Y	Pathogenic	0.961
MEN1	O00255-1.4	V121A	Pathogenic	0.993
MEN1	O00255-1.4	V121C	Pathogenic	0.922
MEN1	O00255-1.4	V121D	Pathogenic	0.994
MEN1	O00255-1.4	V121E	Pathogenic	0.983
MEN1	O00255-1.4	V121F	Pathogenic	0.979
MEN1	O00255-1.4	V121G	Pathogenic	0.999
MEN1	O00255-1.4	V121H	Pathogenic	0.971
MEN1	O00255-1.4	V121I	Pathogenic	0.943
MEN1	O00255-1.4	V121K	Pathogenic	0.999
MEN1	O00255-1.4	V121L	Pathogenic	0.94
MEN1	O00255-1.4	V121M	Pathogenic	0.881
MEN1	O00255-1.4	V121N	Pathogenic	0.988
MEN1	O00255-1.4	V121P	Pathogenic	0.935
MEN1	O00255-1.4	V121Q	Pathogenic	0.977
MEN1	O00255-1.4	V121R	Pathogenic	1.0
MEN1	O00255-1.4	V121S	Pathogenic	0.994
MEN1	O00255-1.4	V121T	Pathogenic	0.956
MEN1	O00255-1.4	V121W	Pathogenic	0.999
MEN1	O00255-1.4	V121Y	Pathogenic	0.978
MEN1	O00255-1.4	S122A	Pathogenic	0.712
MEN1	O00255-1.4	S122C	Pathogenic	0.934
MEN1	O00255-1.4	S122D	Pathogenic	0.924
MEN1	O00255-1.4	S122E	Pathogenic	0.974
MEN1	O00255-1.4	S122F	Pathogenic	1.0
MEN1	O00255-1.4	S122G	Pathogenic	0.868
MEN1	O00255-1.4	S122H	Pathogenic	0.975
MEN1	O00255-1.4	S122I	Pathogenic	0.999
MEN1	O00255-1.4	S122K	Pathogenic	0.998
MEN1	O00255-1.4	S122L	Pathogenic	0.999
MEN1	O00255-1.4	S122M	Pathogenic	0.997
MEN1	O00255-1.4	S122N	Pathogenic	0.926
MEN1	O00255-1.4	S122P	Pathogenic	0.925
MEN1	O00255-1.4	S122Q	Pathogenic	0.965
MEN1	O00255-1.4	S122R	Pathogenic	0.999
MEN1	O00255-1.4	S122T	Pathogenic	0.866
MEN1	O00255-1.4	S122V	Pathogenic	0.989
MEN1	O00255-1.4	S122W	Pathogenic	1.0
MEN1	O00255-1.4	S122Y	Pathogenic	0.999
MEN1	O00255-1.4	D123A	Pathogenic	0.993
MEN1	O00255-1.4	D123C	Pathogenic	0.991
MEN1	O00255-1.4	D123E	Pathogenic	0.941
MEN1	O00255-1.4	D123F	Pathogenic	1.0
MEN1	O00255-1.4	D123G	Pathogenic	0.997
MEN1	O00255-1.4	D123H	Pathogenic	0.992
MEN1	O00255-1.4	D123I	Pathogenic	1.0
MEN1	O00255-1.4	D123K	Pathogenic	0.994
MEN1	O00255-1.4	D123L	Pathogenic	1.0
MEN1	O00255-1.4	D123M	Pathogenic	0.999
MEN1	O00255-1.4	D123N	Pathogenic	0.871
MEN1	O00255-1.4	D123P	Pathogenic	0.98
MEN1	O00255-1.4	D123Q	Pathogenic	0.981
MEN1	O00255-1.4	D123R	Pathogenic	0.998
MEN1	O00255-1.4	D123S	Pathogenic	0.979
MEN1	O00255-1.4	D123T	Pathogenic	0.961
MEN1	O00255-1.4	D123V	Pathogenic	0.997
MEN1	O00255-1.4	D123W	Pathogenic	1.0
MEN1	O00255-1.4	D123Y	Pathogenic	1.0
MEN1	O00255-1.4	V124A	Pathogenic	0.96
MEN1	O00255-1.4	V124C	Pathogenic	0.675
MEN1	O00255-1.4	V124D	Pathogenic	0.965
MEN1	O00255-1.4	V124E	Pathogenic	0.909
MEN1	O00255-1.4	V124F	Pathogenic	0.891
MEN1	O00255-1.4	V124G	Pathogenic	0.995
MEN1	O00255-1.4	V124H	Pathogenic	0.856
MEN1	O00255-1.4	V124I	Pathogenic	0.743
MEN1	O00255-1.4	V124K	Pathogenic	0.992
MEN1	O00255-1.4	V124L	Pathogenic	0.734
MEN1	O00255-1.4	V124M	Pathogenic	0.563
MEN1	O00255-1.4	V124N	Pathogenic	0.935
MEN1	O00255-1.4	V124P	Pathogenic	0.715
MEN1	O00255-1.4	V124Q	Pathogenic	0.88
MEN1	O00255-1.4	V124R	Pathogenic	0.997
MEN1	O00255-1.4	V124S	Pathogenic	0.968
MEN1	O00255-1.4	V124T	Pathogenic	0.79
MEN1	O00255-1.4	V124W	Pathogenic	0.994
MEN1	O00255-1.4	V124Y	Pathogenic	0.885
MEN1	O00255-1.4	I125A	Pathogenic	1.0
MEN1	O00255-1.4	I125C	Pathogenic	0.995
MEN1	O00255-1.4	I125D	Pathogenic	1.0
MEN1	O00255-1.4	I125E	Pathogenic	0.998
MEN1	O00255-1.4	I125F	Pathogenic	0.878
MEN1	O00255-1.4	I125G	Pathogenic	1.0
MEN1	O00255-1.4	I125H	Pathogenic	0.989
MEN1	O00255-1.4	I125K	Pathogenic	0.999
MEN1	O00255-1.4	I125L	Pathogenic	0.764
MEN1	O00255-1.4	I125M	Pathogenic	0.881
MEN1	O00255-1.4	I125N	Pathogenic	0.999
MEN1	O00255-1.4	I125P	Pathogenic	0.996
MEN1	O00255-1.4	I125Q	Pathogenic	0.995
MEN1	O00255-1.4	I125R	Pathogenic	1.0
MEN1	O00255-1.4	I125S	Pathogenic	1.0
MEN1	O00255-1.4	I125T	Pathogenic	0.998
MEN1	O00255-1.4	I125V	Pathogenic	0.965
MEN1	O00255-1.4	I125W	Pathogenic	0.993
MEN1	O00255-1.4	I125Y	Pathogenic	0.979
MEN1	O00255-1.4	W126A	Pathogenic	1.0
MEN1	O00255-1.4	W126C	Pathogenic	1.0
MEN1	O00255-1.4	W126D	Pathogenic	1.0
MEN1	O00255-1.4	W126E	Pathogenic	1.0
MEN1	O00255-1.4	W126F	Pathogenic	0.999
MEN1	O00255-1.4	W126G	Pathogenic	1.0
MEN1	O00255-1.4	W126H	Pathogenic	1.0
MEN1	O00255-1.4	W126I	Pathogenic	1.0
MEN1	O00255-1.4	W126K	Pathogenic	1.0
MEN1	O00255-1.4	W126L	Pathogenic	1.0
MEN1	O00255-1.4	W126M	Pathogenic	1.0
MEN1	O00255-1.4	W126N	Pathogenic	1.0
MEN1	O00255-1.4	W126P	Pathogenic	1.0
MEN1	O00255-1.4	W126Q	Pathogenic	1.0
MEN1	O00255-1.4	W126R	Pathogenic	1.0
MEN1	O00255-1.4	W126S	Pathogenic	1.0
MEN1	O00255-1.4	W126T	Pathogenic	1.0
MEN1	O00255-1.4	W126V	Pathogenic	1.0
MEN1	O00255-1.4	W126Y	Pathogenic	0.999
MEN1	O00255-1.4	N127A	Pathogenic	0.994
MEN1	O00255-1.4	N127C	Pathogenic	0.993
MEN1	O00255-1.4	N127D	Pathogenic	0.88
MEN1	O00255-1.4	N127E	Pathogenic	0.919
MEN1	O00255-1.4	N127F	Pathogenic	1.0
MEN1	O00255-1.4	N127G	Pathogenic	0.997
MEN1	O00255-1.4	N127H	Pathogenic	0.985
MEN1	O00255-1.4	N127I	Pathogenic	0.999
MEN1	O00255-1.4	N127K	Pathogenic	0.993
MEN1	O00255-1.4	N127L	Pathogenic	0.999
MEN1	O00255-1.4	N127M	Pathogenic	0.999
MEN1	O00255-1.4	N127P	Pathogenic	0.984
MEN1	O00255-1.4	N127Q	Pathogenic	0.967
MEN1	O00255-1.4	N127R	Pathogenic	0.997
MEN1	O00255-1.4	N127S	Pathogenic	0.982
MEN1	O00255-1.4	N127T	Pathogenic	0.953
MEN1	O00255-1.4	N127V	Pathogenic	0.995
MEN1	O00255-1.4	N127W	Pathogenic	1.0
MEN1	O00255-1.4	N127Y	Pathogenic	0.999
MEN1	O00255-1.4	S128A	Neutral	0.473
MEN1	O00255-1.4	S128C	Pathogenic	0.836
MEN1	O00255-1.4	S128D	Pathogenic	0.814
MEN1	O00255-1.4	S128E	Pathogenic	0.931
MEN1	O00255-1.4	S128F	Pathogenic	0.999
MEN1	O00255-1.4	S128G	Pathogenic	0.705
MEN1	O00255-1.4	S128H	Pathogenic	0.933
MEN1	O00255-1.4	S128I	Pathogenic	0.997
MEN1	O00255-1.4	S128K	Pathogenic	0.994
MEN1	O00255-1.4	S128L	Pathogenic	0.997
MEN1	O00255-1.4	S128M	Pathogenic	0.992
MEN1	O00255-1.4	S128N	Pathogenic	0.82
MEN1	O00255-1.4	S128P	Pathogenic	0.817
MEN1	O00255-1.4	S128Q	Pathogenic	0.909
MEN1	O00255-1.4	S128R	Pathogenic	0.998
MEN1	O00255-1.4	S128T	Pathogenic	0.701
MEN1	O00255-1.4	S128V	Pathogenic	0.97
MEN1	O00255-1.4	S128W	Pathogenic	1.0
MEN1	O00255-1.4	S128Y	Pathogenic	0.997
MEN1	O00255-1.4	L129A	Pathogenic	0.998
MEN1	O00255-1.4	L129C	Pathogenic	0.978
MEN1	O00255-1.4	L129D	Pathogenic	0.998
MEN1	O00255-1.4	L129E	Pathogenic	0.992
MEN1	O00255-1.4	L129F	Pathogenic	0.668
MEN1	O00255-1.4	L129G	Pathogenic	1.0
MEN1	O00255-1.4	L129H	Pathogenic	0.948
MEN1	O00255-1.4	L129I	Neutral	0.445
MEN1	O00255-1.4	L129K	Pathogenic	0.994
MEN1	O00255-1.4	L129M	Pathogenic	0.593
MEN1	O00255-1.4	L129N	Pathogenic	0.997
MEN1	O00255-1.4	L129P	Pathogenic	0.983
MEN1	O00255-1.4	L129Q	Pathogenic	0.976
MEN1	O00255-1.4	L129R	Pathogenic	0.998
MEN1	O00255-1.4	L129S	Pathogenic	0.998
MEN1	O00255-1.4	L129T	Pathogenic	0.988
MEN1	O00255-1.4	L129V	Pathogenic	0.867
MEN1	O00255-1.4	L129W	Pathogenic	0.975
MEN1	O00255-1.4	L129Y	Pathogenic	0.906
MEN1	O00255-1.4	S130A	Neutral	0.108
MEN1	O00255-1.4	S130C	Neutral	0.408
MEN1	O00255-1.4	S130D	Neutral	0.372
MEN1	O00255-1.4	S130E	Pathogenic	0.647
MEN1	O00255-1.4	S130F	Pathogenic	0.991
MEN1	O00255-1.4	S130G	Neutral	0.244
MEN1	O00255-1.4	S130H	Pathogenic	0.654
MEN1	O00255-1.4	S130I	Pathogenic	0.979
MEN1	O00255-1.4	S130K	Pathogenic	0.958
MEN1	O00255-1.4	S130L	Pathogenic	0.976
MEN1	O00255-1.4	S130M	Pathogenic	0.946
MEN1	O00255-1.4	S130N	Neutral	0.381
MEN1	O00255-1.4	S130P	Neutral	0.377
MEN1	O00255-1.4	S130Q	Pathogenic	0.575
MEN1	O00255-1.4	S130R	Pathogenic	0.985
MEN1	O00255-1.4	S130T	Neutral	0.241
MEN1	O00255-1.4	S130V	Pathogenic	0.815
MEN1	O00255-1.4	S130W	Pathogenic	0.999
MEN1	O00255-1.4	S130Y	Pathogenic	0.977
MEN1	O00255-1.4	R131A	Pathogenic	1.0
MEN1	O00255-1.4	R131C	Pathogenic	1.0
MEN1	O00255-1.4	R131D	Pathogenic	0.996
MEN1	O00255-1.4	R131E	Pathogenic	0.986
MEN1	O00255-1.4	R131F	Pathogenic	0.998
MEN1	O00255-1.4	R131G	Pathogenic	1.0
MEN1	O00255-1.4	R131H	Pathogenic	0.992
MEN1	O00255-1.4	R131I	Pathogenic	0.999
MEN1	O00255-1.4	R131K	Pathogenic	0.832
MEN1	O00255-1.4	R131L	Pathogenic	0.999
MEN1	O00255-1.4	R131M	Pathogenic	0.998
MEN1	O00255-1.4	R131N	Pathogenic	0.995
MEN1	O00255-1.4	R131P	Pathogenic	1.0
MEN1	O00255-1.4	R131Q	Pathogenic	0.989
MEN1	O00255-1.4	R131S	Pathogenic	1.0
MEN1	O00255-1.4	R131T	Pathogenic	0.999
MEN1	O00255-1.4	R131V	Pathogenic	1.0
MEN1	O00255-1.4	R131W	Pathogenic	0.999
MEN1	O00255-1.4	R131Y	Pathogenic	0.99
MEN1	O00255-1.4	S132A	Pathogenic	0.707
MEN1	O00255-1.4	S132C	Pathogenic	0.932
MEN1	O00255-1.4	S132D	Pathogenic	0.922
MEN1	O00255-1.4	S132E	Pathogenic	0.973
MEN1	O00255-1.4	S132F	Pathogenic	1.0
MEN1	O00255-1.4	S132G	Pathogenic	0.865
MEN1	O00255-1.4	S132H	Pathogenic	0.974
MEN1	O00255-1.4	S132I	Pathogenic	0.999
MEN1	O00255-1.4	S132K	Pathogenic	0.998
MEN1	O00255-1.4	S132L	Pathogenic	0.999
MEN1	O00255-1.4	S132M	Pathogenic	0.997
MEN1	O00255-1.4	S132N	Pathogenic	0.925
MEN1	O00255-1.4	S132P	Pathogenic	0.923
MEN1	O00255-1.4	S132Q	Pathogenic	0.964
MEN1	O00255-1.4	S132R	Pathogenic	0.999
MEN1	O00255-1.4	S132T	Pathogenic	0.863
MEN1	O00255-1.4	S132V	Pathogenic	0.989
MEN1	O00255-1.4	S132W	Pathogenic	1.0
MEN1	O00255-1.4	S132Y	Pathogenic	0.999
MEN1	O00255-1.4	Y133A	Pathogenic	1.0
MEN1	O00255-1.4	Y133C	Pathogenic	0.996
MEN1	O00255-1.4	Y133D	Pathogenic	1.0
MEN1	O00255-1.4	Y133E	Pathogenic	0.998
MEN1	O00255-1.4	Y133F	Pathogenic	0.94
MEN1	O00255-1.4	Y133G	Pathogenic	1.0
MEN1	O00255-1.4	Y133H	Pathogenic	0.983
MEN1	O00255-1.4	Y133I	Pathogenic	0.979
MEN1	O00255-1.4	Y133K	Pathogenic	0.992
MEN1	O00255-1.4	Y133L	Pathogenic	0.975
MEN1	O00255-1.4	Y133M	Pathogenic	0.948
MEN1	O00255-1.4	Y133N	Pathogenic	0.999
MEN1	O00255-1.4	Y133P	Pathogenic	0.996
MEN1	O00255-1.4	Y133Q	Pathogenic	0.994
MEN1	O00255-1.4	Y133R	Pathogenic	0.993
MEN1	O00255-1.4	Y133S	Pathogenic	1.0
MEN1	O00255-1.4	Y133T	Pathogenic	0.997
MEN1	O00255-1.4	Y133V	Pathogenic	0.987
MEN1	O00255-1.4	Y133W	Pathogenic	0.991
MEN1	O00255-1.4	F134A	Pathogenic	0.998
MEN1	O00255-1.4	F134C	Pathogenic	0.979
MEN1	O00255-1.4	F134D	Pathogenic	0.998
MEN1	O00255-1.4	F134E	Pathogenic	0.992
MEN1	O00255-1.4	F134G	Pathogenic	1.0
MEN1	O00255-1.4	F134H	Pathogenic	0.941
MEN1	O00255-1.4	F134I	Neutral	0.402
MEN1	O00255-1.4	F134K	Pathogenic	0.969
MEN1	O00255-1.4	F134L	Neutral	0.431
MEN1	O00255-1.4	F134M	Pathogenic	0.619
MEN1	O00255-1.4	F134N	Pathogenic	0.997
MEN1	O00255-1.4	F134P	Pathogenic	0.984
MEN1	O00255-1.4	F134Q	Pathogenic	0.977
MEN1	O00255-1.4	F134R	Pathogenic	0.988
MEN1	O00255-1.4	F134S	Pathogenic	0.998
MEN1	O00255-1.4	F134T	Pathogenic	0.989
MEN1	O00255-1.4	F134V	Pathogenic	0.879
MEN1	O00255-1.4	F134W	Pathogenic	0.823
MEN1	O00255-1.4	F134Y	Pathogenic	0.592
MEN1	O00255-1.4	K135A	Pathogenic	1.0
MEN1	O00255-1.4	K135C	Pathogenic	1.0
MEN1	O00255-1.4	K135D	Pathogenic	0.987
MEN1	O00255-1.4	K135E	Pathogenic	0.957
MEN1	O00255-1.4	K135F	Pathogenic	0.995
MEN1	O00255-1.4	K135G	Pathogenic	1.0
MEN1	O00255-1.4	K135H	Pathogenic	0.978
MEN1	O00255-1.4	K135I	Pathogenic	0.998
MEN1	O00255-1.4	K135L	Pathogenic	0.997
MEN1	O00255-1.4	K135M	Pathogenic	0.994
MEN1	O00255-1.4	K135N	Pathogenic	0.985
MEN1	O00255-1.4	K135P	Pathogenic	0.999
MEN1	O00255-1.4	K135Q	Pathogenic	0.968
MEN1	O00255-1.4	K135R	Pathogenic	0.822
MEN1	O00255-1.4	K135S	Pathogenic	0.999
MEN1	O00255-1.4	K135T	Pathogenic	0.997
MEN1	O00255-1.4	K135V	Pathogenic	0.999
MEN1	O00255-1.4	K135W	Pathogenic	1.0
MEN1	O00255-1.4	K135Y	Pathogenic	0.988
MEN1	O00255-1.4	D136A	Pathogenic	0.995
MEN1	O00255-1.4	D136C	Pathogenic	0.994
MEN1	O00255-1.4	D136E	Pathogenic	0.958
MEN1	O00255-1.4	D136F	Pathogenic	1.0
MEN1	O00255-1.4	D136G	Pathogenic	0.998
MEN1	O00255-1.4	D136H	Pathogenic	0.995
MEN1	O00255-1.4	D136I	Pathogenic	1.0
MEN1	O00255-1.4	D136K	Pathogenic	0.995
MEN1	O00255-1.4	D136L	Pathogenic	1.0
MEN1	O00255-1.4	D136M	Pathogenic	0.999
MEN1	O00255-1.4	D136N	Pathogenic	0.906
MEN1	O00255-1.4	D136P	Pathogenic	0.986
MEN1	O00255-1.4	D136Q	Pathogenic	0.987
MEN1	O00255-1.4	D136R	Pathogenic	0.998
MEN1	O00255-1.4	D136S	Pathogenic	0.985
MEN1	O00255-1.4	D136T	Pathogenic	0.972
MEN1	O00255-1.4	D136V	Pathogenic	0.998
MEN1	O00255-1.4	D136W	Pathogenic	1.0
MEN1	O00255-1.4	D136Y	Pathogenic	1.0
MEN1	O00255-1.4	R137A	Pathogenic	1.0
MEN1	O00255-1.4	R137C	Pathogenic	1.0
MEN1	O00255-1.4	R137D	Pathogenic	0.995
MEN1	O00255-1.4	R137E	Pathogenic	0.983
MEN1	O00255-1.4	R137F	Pathogenic	0.998
MEN1	O00255-1.4	R137G	Pathogenic	1.0
MEN1	O00255-1.4	R137H	Pathogenic	0.99
MEN1	O00255-1.4	R137I	Pathogenic	0.999
MEN1	O00255-1.4	R137K	Pathogenic	0.805
MEN1	O00255-1.4	R137L	Pathogenic	0.999
MEN1	O00255-1.4	R137M	Pathogenic	0.998
MEN1	O00255-1.4	R137N	Pathogenic	0.994
MEN1	O00255-1.4	R137P	Pathogenic	1.0
MEN1	O00255-1.4	R137Q	Pathogenic	0.987
MEN1	O00255-1.4	R137S	Pathogenic	1.0
MEN1	O00255-1.4	R137T	Pathogenic	0.999
MEN1	O00255-1.4	R137V	Pathogenic	0.999
MEN1	O00255-1.4	R137W	Pathogenic	0.999
MEN1	O00255-1.4	R137Y	Pathogenic	0.988
MEN1	O00255-1.4	A138C	Pathogenic	0.848
MEN1	O00255-1.4	A138D	Pathogenic	0.946
MEN1	O00255-1.4	A138E	Pathogenic	0.981
MEN1	O00255-1.4	A138F	Pathogenic	0.999
MEN1	O00255-1.4	A138G	Pathogenic	0.754
MEN1	O00255-1.4	A138H	Pathogenic	0.968
MEN1	O00255-1.4	A138I	Pathogenic	0.997
MEN1	O00255-1.4	A138K	Pathogenic	0.998
MEN1	O00255-1.4	A138L	Pathogenic	0.997
MEN1	O00255-1.4	A138M	Pathogenic	0.993
MEN1	O00255-1.4	A138N	Pathogenic	0.951
MEN1	O00255-1.4	A138P	Pathogenic	0.839
MEN1	O00255-1.4	A138Q	Pathogenic	0.974
MEN1	O00255-1.4	A138R	Pathogenic	0.999
MEN1	O00255-1.4	A138S	Pathogenic	0.538
MEN1	O00255-1.4	A138T	Pathogenic	0.774
MEN1	O00255-1.4	A138V	Pathogenic	0.971
MEN1	O00255-1.4	A138W	Pathogenic	1.0
MEN1	O00255-1.4	A138Y	Pathogenic	0.997
MEN1	O00255-1.4	H139A	Pathogenic	0.999
MEN1	O00255-1.4	H139C	Pathogenic	0.999
MEN1	O00255-1.4	H139D	Pathogenic	0.998
MEN1	O00255-1.4	H139E	Pathogenic	0.992
MEN1	O00255-1.4	H139F	Pathogenic	0.999
MEN1	O00255-1.4	H139G	Pathogenic	1.0
MEN1	O00255-1.4	H139I	Pathogenic	0.998
MEN1	O00255-1.4	H139K	Pathogenic	0.998
MEN1	O00255-1.4	H139L	Pathogenic	0.998
MEN1	O00255-1.4	H139M	Pathogenic	0.995
MEN1	O00255-1.4	H139N	Pathogenic	0.997
MEN1	O00255-1.4	H139P	Pathogenic	0.998
MEN1	O00255-1.4	H139Q	Pathogenic	0.978
MEN1	O00255-1.4	H139R	Pathogenic	0.999
MEN1	O00255-1.4	H139S	Pathogenic	0.999
MEN1	O00255-1.4	H139T	Pathogenic	0.994
MEN1	O00255-1.4	H139V	Pathogenic	0.997
MEN1	O00255-1.4	H139W	Pathogenic	1.0
MEN1	O00255-1.4	H139Y	Pathogenic	0.997
MEN1	O00255-1.4	I140A	Pathogenic	0.997
MEN1	O00255-1.4	I140C	Pathogenic	0.966
MEN1	O00255-1.4	I140D	Pathogenic	0.997
MEN1	O00255-1.4	I140E	Pathogenic	0.988
MEN1	O00255-1.4	I140F	Neutral	0.493
MEN1	O00255-1.4	I140G	Pathogenic	1.0
MEN1	O00255-1.4	I140H	Pathogenic	0.922
MEN1	O00255-1.4	I140K	Pathogenic	0.991
MEN1	O00255-1.4	I140L	Neutral	0.304
MEN1	O00255-1.4	I140M	Neutral	0.498
MEN1	O00255-1.4	I140N	Pathogenic	0.995
MEN1	O00255-1.4	I140P	Pathogenic	0.974
MEN1	O00255-1.4	I140Q	Pathogenic	0.966
MEN1	O00255-1.4	I140R	Pathogenic	0.997
MEN1	O00255-1.4	I140S	Pathogenic	0.998
MEN1	O00255-1.4	I140T	Pathogenic	0.982
MEN1	O00255-1.4	I140V	Pathogenic	0.788
MEN1	O00255-1.4	I140W	Pathogenic	0.95
MEN1	O00255-1.4	I140Y	Pathogenic	0.861
MEN1	O00255-1.4	Q141A	Pathogenic	0.997
MEN1	O00255-1.4	Q141C	Pathogenic	0.997
MEN1	O00255-1.4	Q141D	Pathogenic	0.983
MEN1	O00255-1.4	Q141E	Pathogenic	0.914
MEN1	O00255-1.4	Q141F	Pathogenic	0.998
MEN1	O00255-1.4	Q141G	Pathogenic	0.999
MEN1	O00255-1.4	Q141H	Pathogenic	0.909
MEN1	O00255-1.4	Q141I	Pathogenic	0.996
MEN1	O00255-1.4	Q141K	Pathogenic	0.985
MEN1	O00255-1.4	Q141L	Pathogenic	0.996
MEN1	O00255-1.4	Q141M	Pathogenic	0.989
MEN1	O00255-1.4	Q141N	Pathogenic	0.968
MEN1	O00255-1.4	Q141P	Pathogenic	0.992
MEN1	O00255-1.4	Q141R	Pathogenic	0.994
MEN1	O00255-1.4	Q141S	Pathogenic	0.992
MEN1	O00255-1.4	Q141T	Pathogenic	0.979
MEN1	O00255-1.4	Q141V	Pathogenic	0.99
MEN1	O00255-1.4	Q141W	Pathogenic	1.0
MEN1	O00255-1.4	Q141Y	Pathogenic	0.996
MEN1	O00255-1.4	S142A	Pathogenic	0.753
MEN1	O00255-1.4	S142C	Pathogenic	0.945
MEN1	O00255-1.4	S142D	Pathogenic	0.937
MEN1	O00255-1.4	S142E	Pathogenic	0.979
MEN1	O00255-1.4	S142F	Pathogenic	1.0
MEN1	O00255-1.4	S142G	Pathogenic	0.89
MEN1	O00255-1.4	S142H	Pathogenic	0.979
MEN1	O00255-1.4	S142I	Pathogenic	0.999
MEN1	O00255-1.4	S142K	Pathogenic	0.998
MEN1	O00255-1.4	S142L	Pathogenic	0.999
MEN1	O00255-1.4	S142M	Pathogenic	0.998
MEN1	O00255-1.4	S142N	Pathogenic	0.939
MEN1	O00255-1.4	S142P	Pathogenic	0.938
MEN1	O00255-1.4	S142Q	Pathogenic	0.971
MEN1	O00255-1.4	S142R	Pathogenic	0.999
MEN1	O00255-1.4	S142T	Pathogenic	0.888
MEN1	O00255-1.4	S142V	Pathogenic	0.991
MEN1	O00255-1.4	S142W	Pathogenic	1.0
MEN1	O00255-1.4	S142Y	Pathogenic	0.999
MEN1	O00255-1.4	L143A	Pathogenic	0.996
MEN1	O00255-1.4	L143C	Pathogenic	0.948
MEN1	O00255-1.4	L143D	Pathogenic	0.996
MEN1	O00255-1.4	L143E	Pathogenic	0.981
MEN1	O00255-1.4	L143F	Neutral	0.451
MEN1	O00255-1.4	L143G	Pathogenic	0.999
MEN1	O00255-1.4	L143H	Pathogenic	0.882
MEN1	O00255-1.4	L143I	Neutral	0.247
MEN1	O00255-1.4	L143K	Pathogenic	0.984
MEN1	O00255-1.4	L143M	Neutral	0.372
MEN1	O00255-1.4	L143N	Pathogenic	0.992
MEN1	O00255-1.4	L143P	Pathogenic	0.959
MEN1	O00255-1.4	L143Q	Pathogenic	0.944
MEN1	O00255-1.4	L143R	Pathogenic	0.994
MEN1	O00255-1.4	L143S	Pathogenic	0.996
MEN1	O00255-1.4	L143T	Pathogenic	0.972
MEN1	O00255-1.4	L143V	Pathogenic	0.727
MEN1	O00255-1.4	L143W	Pathogenic	0.941
MEN1	O00255-1.4	L143Y	Pathogenic	0.797
MEN1	O00255-1.4	F144A	Pathogenic	0.999
MEN1	O00255-1.4	F144C	Pathogenic	0.988
MEN1	O00255-1.4	F144D	Pathogenic	0.999
MEN1	O00255-1.4	F144E	Pathogenic	0.995
MEN1	O00255-1.4	F144G	Pathogenic	1.0
MEN1	O00255-1.4	F144H	Pathogenic	0.966
MEN1	O00255-1.4	F144I	Pathogenic	0.54
MEN1	O00255-1.4	F144K	Pathogenic	0.982
MEN1	O00255-1.4	F144L	Pathogenic	0.57
MEN1	O00255-1.4	F144M	Pathogenic	0.739
MEN1	O00255-1.4	F144N	Pathogenic	0.998
MEN1	O00255-1.4	F144P	Pathogenic	0.991
MEN1	O00255-1.4	F144Q	Pathogenic	0.987
MEN1	O00255-1.4	F144R	Pathogenic	0.993
MEN1	O00255-1.4	F144S	Pathogenic	0.999
MEN1	O00255-1.4	F144T	Pathogenic	0.994
MEN1	O00255-1.4	F144V	Pathogenic	0.927
MEN1	O00255-1.4	F144W	Pathogenic	0.891
MEN1	O00255-1.4	F144Y	Pathogenic	0.717
MEN1	O00255-1.4	S145A	Pathogenic	0.81
MEN1	O00255-1.4	S145C	Pathogenic	0.96
MEN1	O00255-1.4	S145D	Pathogenic	0.954
MEN1	O00255-1.4	S145E	Pathogenic	0.985
MEN1	O00255-1.4	S145F	Pathogenic	1.0
MEN1	O00255-1.4	S145G	Pathogenic	0.919
MEN1	O00255-1.4	S145H	Pathogenic	0.985
MEN1	O00255-1.4	S145I	Pathogenic	0.999
MEN1	O00255-1.4	S145K	Pathogenic	0.999
MEN1	O00255-1.4	S145L	Pathogenic	0.999
MEN1	O00255-1.4	S145M	Pathogenic	0.998
MEN1	O00255-1.4	S145N	Pathogenic	0.956
MEN1	O00255-1.4	S145P	Pathogenic	0.955
MEN1	O00255-1.4	S145Q	Pathogenic	0.979
MEN1	O00255-1.4	S145R	Pathogenic	1.0
MEN1	O00255-1.4	S145T	Pathogenic	0.918
MEN1	O00255-1.4	S145V	Pathogenic	0.994
MEN1	O00255-1.4	S145W	Pathogenic	1.0
MEN1	O00255-1.4	S145Y	Pathogenic	0.999
MEN1	O00255-1.4	F146A	Pathogenic	0.997
MEN1	O00255-1.4	F146C	Pathogenic	0.959
MEN1	O00255-1.4	F146D	Pathogenic	0.997
MEN1	O00255-1.4	F146E	Pathogenic	0.984
MEN1	O00255-1.4	F146G	Pathogenic	1.0
MEN1	O00255-1.4	F146H	Pathogenic	0.889
MEN1	O00255-1.4	F146I	Neutral	0.251
MEN1	O00255-1.4	F146K	Pathogenic	0.94
MEN1	O00255-1.4	F146L	Neutral	0.275
MEN1	O00255-1.4	F146M	Neutral	0.448
MEN1	O00255-1.4	F146N	Pathogenic	0.994
MEN1	O00255-1.4	F146P	Pathogenic	0.968
MEN1	O00255-1.4	F146Q	Pathogenic	0.956
MEN1	O00255-1.4	F146R	Pathogenic	0.977
MEN1	O00255-1.4	F146S	Pathogenic	0.997
MEN1	O00255-1.4	F146T	Pathogenic	0.978
MEN1	O00255-1.4	F146V	Pathogenic	0.785
MEN1	O00255-1.4	F146W	Pathogenic	0.699
MEN1	O00255-1.4	F146Y	Neutral	0.42
MEN1	O00255-1.4	I147A	Pathogenic	0.992
MEN1	O00255-1.4	I147C	Pathogenic	0.911
MEN1	O00255-1.4	I147D	Pathogenic	0.993
MEN1	O00255-1.4	I147E	Pathogenic	0.966
MEN1	O00255-1.4	I147F	Neutral	0.258
MEN1	O00255-1.4	I147G	Pathogenic	0.999
MEN1	O00255-1.4	I147H	Pathogenic	0.808
MEN1	O00255-1.4	I147K	Pathogenic	0.974
MEN1	O00255-1.4	I147L	Neutral	0.135
MEN1	O00255-1.4	I147M	Neutral	0.262
MEN1	O00255-1.4	I147N	Pathogenic	0.986
MEN1	O00255-1.4	I147P	Pathogenic	0.929
MEN1	O00255-1.4	I147Q	Pathogenic	0.91
MEN1	O00255-1.4	I147R	Pathogenic	0.99
MEN1	O00255-1.4	I147S	Pathogenic	0.993
MEN1	O00255-1.4	I147T	Pathogenic	0.952
MEN1	O00255-1.4	I147V	Pathogenic	0.572
MEN1	O00255-1.4	I147W	Pathogenic	0.872
MEN1	O00255-1.4	I147Y	Pathogenic	0.689
MEN1	O00255-1.4	T148A	Neutral	0.32
MEN1	O00255-1.4	T148C	Neutral	0.266
MEN1	O00255-1.4	T148D	Neutral	0.289
MEN1	O00255-1.4	T148E	Neutral	0.482
MEN1	O00255-1.4	T148F	Pathogenic	0.951
MEN1	O00255-1.4	T148G	Pathogenic	0.754
MEN1	O00255-1.4	T148H	Neutral	0.357
MEN1	O00255-1.4	T148I	Pathogenic	0.892
MEN1	O00255-1.4	T148K	Pathogenic	0.92
MEN1	O00255-1.4	T148L	Pathogenic	0.874
MEN1	O00255-1.4	T148M	Pathogenic	0.765
MEN1	O00255-1.4	T148N	Neutral	0.238
MEN1	O00255-1.4	T148P	Neutral	0.149
MEN1	O00255-1.4	T148Q	Neutral	0.407
MEN1	O00255-1.4	T148R	Pathogenic	0.969
MEN1	O00255-1.4	T148S	Neutral	0.296
MEN1	O00255-1.4	T148V	Neutral	0.42
MEN1	O00255-1.4	T148W	Pathogenic	0.997
MEN1	O00255-1.4	T148Y	Pathogenic	0.888
MEN1	O00255-1.4	G149A	Neutral	0.112
MEN1	O00255-1.4	G149C	Pathogenic	0.65
MEN1	O00255-1.4	G149D	Pathogenic	0.629
MEN1	O00255-1.4	G149E	Pathogenic	0.848
MEN1	O00255-1.4	G149F	Pathogenic	0.996
MEN1	O00255-1.4	G149H	Pathogenic	0.828
MEN1	O00255-1.4	G149I	Pathogenic	0.992
MEN1	O00255-1.4	G149K	Pathogenic	0.986
MEN1	O00255-1.4	G149L	Pathogenic	0.991
MEN1	O00255-1.4	G149M	Pathogenic	0.979
MEN1	O00255-1.4	G149N	Pathogenic	0.638
MEN1	O00255-1.4	G149P	Pathogenic	0.606
MEN1	O00255-1.4	G149Q	Pathogenic	0.804
MEN1	O00255-1.4	G149R	Pathogenic	0.995
MEN1	O00255-1.4	G149S	Neutral	0.112
MEN1	O00255-1.4	G149T	Neutral	0.476
MEN1	O00255-1.4	G149V	Pathogenic	0.918
MEN1	O00255-1.4	G149W	Pathogenic	1.0
MEN1	O00255-1.4	G149Y	Pathogenic	0.991
MEN1	O00255-1.4	W150A	Pathogenic	1.0
MEN1	O00255-1.4	W150C	Pathogenic	0.999
MEN1	O00255-1.4	W150D	Pathogenic	1.0
MEN1	O00255-1.4	W150E	Pathogenic	1.0
MEN1	O00255-1.4	W150F	Pathogenic	0.856
MEN1	O00255-1.4	W150G	Pathogenic	1.0
MEN1	O00255-1.4	W150H	Pathogenic	0.997
MEN1	O00255-1.4	W150I	Pathogenic	0.944
MEN1	O00255-1.4	W150K	Pathogenic	0.999
MEN1	O00255-1.4	W150L	Pathogenic	0.949
MEN1	O00255-1.4	W150M	Pathogenic	0.974
MEN1	O00255-1.4	W150N	Pathogenic	1.0
MEN1	O00255-1.4	W150P	Pathogenic	0.999
MEN1	O00255-1.4	W150Q	Pathogenic	0.999
MEN1	O00255-1.4	W150R	Pathogenic	0.996
MEN1	O00255-1.4	W150S	Pathogenic	1.0
MEN1	O00255-1.4	W150T	Pathogenic	0.999
MEN1	O00255-1.4	W150V	Pathogenic	0.994
MEN1	O00255-1.4	W150Y	Pathogenic	0.932
MEN1	O00255-1.4	S151A	Neutral	0.029
MEN1	O00255-1.4	S151C	Neutral	0.147
MEN1	O00255-1.4	S151D	Neutral	0.129
MEN1	O00255-1.4	S151E	Neutral	0.315
MEN1	O00255-1.4	S151F	Pathogenic	0.963
MEN1	O00255-1.4	S151G	Neutral	0.075
MEN1	O00255-1.4	S151H	Neutral	0.321
MEN1	O00255-1.4	S151I	Pathogenic	0.922
MEN1	O00255-1.4	S151K	Pathogenic	0.85
MEN1	O00255-1.4	S151L	Pathogenic	0.909
MEN1	O00255-1.4	S151M	Pathogenic	0.815
MEN1	O00255-1.4	S151N	Neutral	0.134
MEN1	O00255-1.4	S151P	Neutral	0.132
MEN1	O00255-1.4	S151Q	Neutral	0.253
MEN1	O00255-1.4	S151R	Pathogenic	0.942
MEN1	O00255-1.4	S151T	Neutral	0.074
MEN1	O00255-1.4	S151V	Pathogenic	0.526
MEN1	O00255-1.4	S151W	Pathogenic	0.998
MEN1	O00255-1.4	S151Y	Pathogenic	0.915
MEN1	O00255-1.4	P152A	Neutral	0.085
MEN1	O00255-1.4	P152C	Neutral	0.019
MEN1	O00255-1.4	P152D	Neutral	0.093
MEN1	O00255-1.4	P152E	Neutral	0.241
MEN1	O00255-1.4	P152F	Pathogenic	0.625
MEN1	O00255-1.4	P152G	Neutral	0.401
MEN1	O00255-1.4	P152H	Neutral	0.159
MEN1	O00255-1.4	P152I	Neutral	0.415
MEN1	O00255-1.4	P152K	Pathogenic	0.797
MEN1	O00255-1.4	P152L	Neutral	0.375
MEN1	O00255-1.4	P152M	Neutral	0.209
MEN1	O00255-1.4	P152N	Neutral	0.108
MEN1	O00255-1.4	P152Q	Neutral	0.19
MEN1	O00255-1.4	P152R	Pathogenic	0.918
MEN1	O00255-1.4	P152S	Neutral	0.094
MEN1	O00255-1.4	P152T	Neutral	0.022
MEN1	O00255-1.4	P152V	Neutral	0.059
MEN1	O00255-1.4	P152W	Pathogenic	0.966
MEN1	O00255-1.4	P152Y	Neutral	0.391
MEN1	O00255-1.4	V153A	Neutral	0.02
MEN1	O00255-1.4	V153C	Neutral	0.002
MEN1	O00255-1.4	V153D	Neutral	0.023
MEN1	O00255-1.4	V153E	Neutral	0.008
MEN1	O00255-1.4	V153F	Neutral	0.007
MEN1	O00255-1.4	V153G	Neutral	0.141
MEN1	O00255-1.4	V153H	Neutral	0.005
MEN1	O00255-1.4	V153I	Neutral	0.002
MEN1	O00255-1.4	V153K	Neutral	0.093
MEN1	O00255-1.4	V153L	Neutral	0.002
MEN1	O00255-1.4	V153M	Neutral	0.001
MEN1	O00255-1.4	V153N	Neutral	0.012
MEN1	O00255-1.4	V153P	Neutral	0.002
MEN1	O00255-1.4	V153Q	Neutral	0.006
MEN1	O00255-1.4	V153R	Neutral	0.228
MEN1	O00255-1.4	V153S	Neutral	0.025
MEN1	O00255-1.4	V153T	Neutral	0.003
MEN1	O00255-1.4	V153W	Neutral	0.116
MEN1	O00255-1.4	V153Y	Neutral	0.006
MEN1	O00255-1.4	G154A	Pathogenic	0.86
MEN1	O00255-1.4	G154C	Pathogenic	0.989
MEN1	O00255-1.4	G154D	Pathogenic	0.988
MEN1	O00255-1.4	G154E	Pathogenic	0.996
MEN1	O00255-1.4	G154F	Pathogenic	1.0
MEN1	O00255-1.4	G154H	Pathogenic	0.996
MEN1	O00255-1.4	G154I	Pathogenic	1.0
MEN1	O00255-1.4	G154K	Pathogenic	1.0
MEN1	O00255-1.4	G154L	Pathogenic	1.0
MEN1	O00255-1.4	G154M	Pathogenic	1.0
MEN1	O00255-1.4	G154N	Pathogenic	0.989
MEN1	O00255-1.4	G154P	Pathogenic	0.987
MEN1	O00255-1.4	G154Q	Pathogenic	0.995
MEN1	O00255-1.4	G154R	Pathogenic	1.0
MEN1	O00255-1.4	G154S	Pathogenic	0.861
MEN1	O00255-1.4	G154T	Pathogenic	0.978
MEN1	O00255-1.4	G154V	Pathogenic	0.998
MEN1	O00255-1.4	G154W	Pathogenic	1.0
MEN1	O00255-1.4	G154Y	Pathogenic	1.0
MEN1	O00255-1.4	T155A	Pathogenic	0.628
MEN1	O00255-1.4	T155C	Pathogenic	0.565
MEN1	O00255-1.4	T155D	Pathogenic	0.592
MEN1	O00255-1.4	T155E	Pathogenic	0.77
MEN1	O00255-1.4	T155F	Pathogenic	0.986
MEN1	O00255-1.4	T155G	Pathogenic	0.917
MEN1	O00255-1.4	T155H	Pathogenic	0.666
MEN1	O00255-1.4	T155I	Pathogenic	0.967
MEN1	O00255-1.4	T155K	Pathogenic	0.976
MEN1	O00255-1.4	T155L	Pathogenic	0.962
MEN1	O00255-1.4	T155M	Pathogenic	0.921
MEN1	O00255-1.4	T155N	Pathogenic	0.529
MEN1	O00255-1.4	T155P	Neutral	0.385
MEN1	O00255-1.4	T155Q	Pathogenic	0.711
MEN1	O00255-1.4	T155R	Pathogenic	0.991
MEN1	O00255-1.4	T155S	Pathogenic	0.601
MEN1	O00255-1.4	T155V	Pathogenic	0.722
MEN1	O00255-1.4	T155W	Pathogenic	0.999
MEN1	O00255-1.4	T155Y	Pathogenic	0.966
MEN1	O00255-1.4	K156A	Pathogenic	1.0
MEN1	O00255-1.4	K156C	Pathogenic	1.0
MEN1	O00255-1.4	K156D	Pathogenic	0.992
MEN1	O00255-1.4	K156E	Pathogenic	0.971
MEN1	O00255-1.4	K156F	Pathogenic	0.997
MEN1	O00255-1.4	K156G	Pathogenic	1.0
MEN1	O00255-1.4	K156H	Pathogenic	0.985
MEN1	O00255-1.4	K156I	Pathogenic	0.999
MEN1	O00255-1.4	K156L	Pathogenic	0.998
MEN1	O00255-1.4	K156M	Pathogenic	0.996
MEN1	O00255-1.4	K156N	Pathogenic	0.99
MEN1	O00255-1.4	K156P	Pathogenic	0.999
MEN1	O00255-1.4	K156Q	Pathogenic	0.979
MEN1	O00255-1.4	K156R	Pathogenic	0.875
MEN1	O00255-1.4	K156S	Pathogenic	0.999
MEN1	O00255-1.4	K156T	Pathogenic	0.998
MEN1	O00255-1.4	K156V	Pathogenic	0.999
MEN1	O00255-1.4	K156W	Pathogenic	1.0
MEN1	O00255-1.4	K156Y	Pathogenic	0.992
MEN1	O00255-1.4	L157A	Pathogenic	0.999
MEN1	O00255-1.4	L157C	Pathogenic	0.988
MEN1	O00255-1.4	L157D	Pathogenic	0.999
MEN1	O00255-1.4	L157E	Pathogenic	0.996
MEN1	O00255-1.4	L157F	Pathogenic	0.788
MEN1	O00255-1.4	L157G	Pathogenic	1.0
MEN1	O00255-1.4	L157H	Pathogenic	0.971
MEN1	O00255-1.4	L157I	Pathogenic	0.597
MEN1	O00255-1.4	L157K	Pathogenic	0.997
MEN1	O00255-1.4	L157M	Pathogenic	0.729
MEN1	O00255-1.4	L157N	Pathogenic	0.998
MEN1	O00255-1.4	L157P	Pathogenic	0.991
MEN1	O00255-1.4	L157Q	Pathogenic	0.987
MEN1	O00255-1.4	L157R	Pathogenic	0.999
MEN1	O00255-1.4	L157S	Pathogenic	0.999
MEN1	O00255-1.4	L157T	Pathogenic	0.994
MEN1	O00255-1.4	L157V	Pathogenic	0.923
MEN1	O00255-1.4	L157W	Pathogenic	0.986
MEN1	O00255-1.4	L157Y	Pathogenic	0.947
MEN1	O00255-1.4	D158A	Pathogenic	0.996
MEN1	O00255-1.4	D158C	Pathogenic	0.994
MEN1	O00255-1.4	D158E	Pathogenic	0.962
MEN1	O00255-1.4	D158F	Pathogenic	1.0
MEN1	O00255-1.4	D158G	Pathogenic	0.998
MEN1	O00255-1.4	D158H	Pathogenic	0.995
MEN1	O00255-1.4	D158I	Pathogenic	1.0
MEN1	O00255-1.4	D158K	Pathogenic	0.996
MEN1	O00255-1.4	D158L	Pathogenic	1.0
MEN1	O00255-1.4	D158M	Pathogenic	1.0
MEN1	O00255-1.4	D158N	Pathogenic	0.915
MEN1	O00255-1.4	D158P	Pathogenic	0.987
MEN1	O00255-1.4	D158Q	Pathogenic	0.988
MEN1	O00255-1.4	D158R	Pathogenic	0.999
MEN1	O00255-1.4	D158S	Pathogenic	0.987
MEN1	O00255-1.4	D158T	Pathogenic	0.975
MEN1	O00255-1.4	D158V	Pathogenic	0.998
MEN1	O00255-1.4	D158W	Pathogenic	1.0
MEN1	O00255-1.4	D158Y	Pathogenic	1.0
MEN1	O00255-1.4	S159A	Neutral	0.254
MEN1	O00255-1.4	S159C	Pathogenic	0.659
MEN1	O00255-1.4	S159D	Pathogenic	0.625
MEN1	O00255-1.4	S159E	Pathogenic	0.838
MEN1	O00255-1.4	S159F	Pathogenic	0.997
MEN1	O00255-1.4	S159G	Neutral	0.476
MEN1	O00255-1.4	S159H	Pathogenic	0.842
MEN1	O00255-1.4	S159I	Pathogenic	0.993
MEN1	O00255-1.4	S159K	Pathogenic	0.985
MEN1	O00255-1.4	S159L	Pathogenic	0.991
MEN1	O00255-1.4	S159M	Pathogenic	0.98
MEN1	O00255-1.4	S159N	Pathogenic	0.634
MEN1	O00255-1.4	S159P	Pathogenic	0.63
MEN1	O00255-1.4	S159Q	Pathogenic	0.792
MEN1	O00255-1.4	S159R	Pathogenic	0.995
MEN1	O00255-1.4	S159T	Neutral	0.471
MEN1	O00255-1.4	S159V	Pathogenic	0.926
MEN1	O00255-1.4	S159W	Pathogenic	1.0
MEN1	O00255-1.4	S159Y	Pathogenic	0.992
MEN1	O00255-1.4	S160A	Neutral	0.122
MEN1	O00255-1.4	S160C	Neutral	0.44
MEN1	O00255-1.4	S160D	Neutral	0.404
MEN1	O00255-1.4	S160E	Pathogenic	0.677
MEN1	O00255-1.4	S160F	Pathogenic	0.992
MEN1	O00255-1.4	S160G	Neutral	0.269
MEN1	O00255-1.4	S160H	Pathogenic	0.684
MEN1	O00255-1.4	S160I	Pathogenic	0.982
MEN1	O00255-1.4	S160K	Pathogenic	0.963
MEN1	O00255-1.4	S160L	Pathogenic	0.979
MEN1	O00255-1.4	S160M	Pathogenic	0.953
MEN1	O00255-1.4	S160N	Neutral	0.413
MEN1	O00255-1.4	S160P	Neutral	0.409
MEN1	O00255-1.4	S160Q	Pathogenic	0.607
MEN1	O00255-1.4	S160R	Pathogenic	0.987
MEN1	O00255-1.4	S160T	Neutral	0.266
MEN1	O00255-1.4	S160V	Pathogenic	0.835
MEN1	O00255-1.4	S160W	Pathogenic	1.0
MEN1	O00255-1.4	S160Y	Pathogenic	0.98
MEN1	O00255-1.4	G161A	Pathogenic	0.949
MEN1	O00255-1.4	G161C	Pathogenic	0.996
MEN1	O00255-1.4	G161D	Pathogenic	0.996
MEN1	O00255-1.4	G161E	Pathogenic	0.999
MEN1	O00255-1.4	G161F	Pathogenic	1.0
MEN1	O00255-1.4	G161H	Pathogenic	0.999
MEN1	O00255-1.4	G161I	Pathogenic	1.0
MEN1	O00255-1.4	G161K	Pathogenic	1.0
MEN1	O00255-1.4	G161L	Pathogenic	1.0
MEN1	O00255-1.4	G161M	Pathogenic	1.0
MEN1	O00255-1.4	G161N	Pathogenic	0.996
MEN1	O00255-1.4	G161P	Pathogenic	0.996
MEN1	O00255-1.4	G161Q	Pathogenic	0.998
MEN1	O00255-1.4	G161R	Pathogenic	1.0
MEN1	O00255-1.4	G161S	Pathogenic	0.95
MEN1	O00255-1.4	G161T	Pathogenic	0.993
MEN1	O00255-1.4	G161V	Pathogenic	0.999
MEN1	O00255-1.4	G161W	Pathogenic	1.0
MEN1	O00255-1.4	G161Y	Pathogenic	1.0
MEN1	O00255-1.4	V162A	Pathogenic	0.992
MEN1	O00255-1.4	V162C	Pathogenic	0.912
MEN1	O00255-1.4	V162D	Pathogenic	0.993
MEN1	O00255-1.4	V162E	Pathogenic	0.98
MEN1	O00255-1.4	V162F	Pathogenic	0.976
MEN1	O00255-1.4	V162G	Pathogenic	0.999
MEN1	O00255-1.4	V162H	Pathogenic	0.967
MEN1	O00255-1.4	V162I	Pathogenic	0.935
MEN1	O00255-1.4	V162K	Pathogenic	0.998
MEN1	O00255-1.4	V162L	Pathogenic	0.932
MEN1	O00255-1.4	V162M	Pathogenic	0.865
MEN1	O00255-1.4	V162N	Pathogenic	0.986
MEN1	O00255-1.4	V162P	Pathogenic	0.926
MEN1	O00255-1.4	V162Q	Pathogenic	0.973
MEN1	O00255-1.4	V162R	Pathogenic	0.999
MEN1	O00255-1.4	V162S	Pathogenic	0.993
MEN1	O00255-1.4	V162T	Pathogenic	0.949
MEN1	O00255-1.4	V162W	Pathogenic	0.999
MEN1	O00255-1.4	V162Y	Pathogenic	0.974
MEN1	O00255-1.4	A163C	Pathogenic	0.95
MEN1	O00255-1.4	A163D	Pathogenic	0.983
MEN1	O00255-1.4	A163E	Pathogenic	0.994
MEN1	O00255-1.4	A163F	Pathogenic	1.0
MEN1	O00255-1.4	A163G	Pathogenic	0.912
MEN1	O00255-1.4	A163H	Pathogenic	0.99
MEN1	O00255-1.4	A163I	Pathogenic	0.999
MEN1	O00255-1.4	A163K	Pathogenic	1.0
MEN1	O00255-1.4	A163L	Pathogenic	0.999
MEN1	O00255-1.4	A163M	Pathogenic	0.998
MEN1	O00255-1.4	A163N	Pathogenic	0.985
MEN1	O00255-1.4	A163P	Pathogenic	0.946
MEN1	O00255-1.4	A163Q	Pathogenic	0.992
MEN1	O00255-1.4	A163R	Pathogenic	1.0
MEN1	O00255-1.4	A163S	Pathogenic	0.798
MEN1	O00255-1.4	A163T	Pathogenic	0.921
MEN1	O00255-1.4	A163V	Pathogenic	0.991
MEN1	O00255-1.4	A163W	Pathogenic	1.0
MEN1	O00255-1.4	A163Y	Pathogenic	0.999
MEN1	O00255-1.4	F164A	Pathogenic	1.0
MEN1	O00255-1.4	F164C	Pathogenic	0.999
MEN1	O00255-1.4	F164D	Pathogenic	1.0
MEN1	O00255-1.4	F164E	Pathogenic	1.0
MEN1	O00255-1.4	F164G	Pathogenic	1.0
MEN1	O00255-1.4	F164H	Pathogenic	0.997
MEN1	O00255-1.4	F164I	Pathogenic	0.939
MEN1	O00255-1.4	F164K	Pathogenic	0.999
MEN1	O00255-1.4	F164L	Pathogenic	0.946
MEN1	O00255-1.4	F164M	Pathogenic	0.974
MEN1	O00255-1.4	F164N	Pathogenic	1.0
MEN1	O00255-1.4	F164P	Pathogenic	0.999
MEN1	O00255-1.4	F164Q	Pathogenic	0.999
MEN1	O00255-1.4	F164R	Pathogenic	0.999
MEN1	O00255-1.4	F164S	Pathogenic	1.0
MEN1	O00255-1.4	F164T	Pathogenic	1.0
MEN1	O00255-1.4	F164V	Pathogenic	0.994
MEN1	O00255-1.4	F164W	Pathogenic	0.991
MEN1	O00255-1.4	F164Y	Pathogenic	0.971
MEN1	O00255-1.4	A165C	Pathogenic	0.944
MEN1	O00255-1.4	A165D	Pathogenic	0.981
MEN1	O00255-1.4	A165E	Pathogenic	0.994
MEN1	O00255-1.4	A165F	Pathogenic	1.0
MEN1	O00255-1.4	A165G	Pathogenic	0.903
MEN1	O00255-1.4	A165H	Pathogenic	0.989
MEN1	O00255-1.4	A165I	Pathogenic	0.999
MEN1	O00255-1.4	A165K	Pathogenic	0.999
MEN1	O00255-1.4	A165L	Pathogenic	0.999
MEN1	O00255-1.4	A165M	Pathogenic	0.998
MEN1	O00255-1.4	A165N	Pathogenic	0.983
MEN1	O00255-1.4	A165P	Pathogenic	0.94
MEN1	O00255-1.4	A165Q	Pathogenic	0.991
MEN1	O00255-1.4	A165R	Pathogenic	1.0
MEN1	O00255-1.4	A165S	Pathogenic	0.778
MEN1	O00255-1.4	A165T	Pathogenic	0.912
MEN1	O00255-1.4	A165V	Pathogenic	0.99
MEN1	O00255-1.4	A165W	Pathogenic	1.0
MEN1	O00255-1.4	A165Y	Pathogenic	0.999
MEN1	O00255-1.4	V166A	Pathogenic	0.995
MEN1	O00255-1.4	V166C	Pathogenic	0.949
MEN1	O00255-1.4	V166D	Pathogenic	0.996
MEN1	O00255-1.4	V166E	Pathogenic	0.989
MEN1	O00255-1.4	V166F	Pathogenic	0.986
MEN1	O00255-1.4	V166G	Pathogenic	0.999
MEN1	O00255-1.4	V166H	Pathogenic	0.981
MEN1	O00255-1.4	V166I	Pathogenic	0.963
MEN1	O00255-1.4	V166K	Pathogenic	0.999
MEN1	O00255-1.4	V166L	Pathogenic	0.961
MEN1	O00255-1.4	V166M	Pathogenic	0.92
MEN1	O00255-1.4	V166N	Pathogenic	0.992
MEN1	O00255-1.4	V166P	Pathogenic	0.957
MEN1	O00255-1.4	V166Q	Pathogenic	0.985
MEN1	O00255-1.4	V166R	Pathogenic	1.0
MEN1	O00255-1.4	V166S	Pathogenic	0.996
MEN1	O00255-1.4	V166T	Pathogenic	0.971
MEN1	O00255-1.4	V166W	Pathogenic	0.999
MEN1	O00255-1.4	V166Y	Pathogenic	0.986
MEN1	O00255-1.4	V167A	Pathogenic	0.993
MEN1	O00255-1.4	V167C	Pathogenic	0.92
MEN1	O00255-1.4	V167D	Pathogenic	0.994
MEN1	O00255-1.4	V167E	Pathogenic	0.982
MEN1	O00255-1.4	V167F	Pathogenic	0.978
MEN1	O00255-1.4	V167G	Pathogenic	0.999
MEN1	O00255-1.4	V167H	Pathogenic	0.971
MEN1	O00255-1.4	V167I	Pathogenic	0.941
MEN1	O00255-1.4	V167K	Pathogenic	0.999
MEN1	O00255-1.4	V167L	Pathogenic	0.939
MEN1	O00255-1.4	V167M	Pathogenic	0.877
MEN1	O00255-1.4	V167N	Pathogenic	0.988
MEN1	O00255-1.4	V167P	Pathogenic	0.933
MEN1	O00255-1.4	V167Q	Pathogenic	0.976
MEN1	O00255-1.4	V167R	Pathogenic	0.999
MEN1	O00255-1.4	V167S	Pathogenic	0.994
MEN1	O00255-1.4	V167T	Pathogenic	0.954
MEN1	O00255-1.4	V167W	Pathogenic	0.999
MEN1	O00255-1.4	V167Y	Pathogenic	0.977
MEN1	O00255-1.4	G168A	Neutral	0.251
MEN1	O00255-1.4	G168C	Pathogenic	0.832
MEN1	O00255-1.4	G168D	Pathogenic	0.819
MEN1	O00255-1.4	G168E	Pathogenic	0.937
MEN1	O00255-1.4	G168F	Pathogenic	0.999
MEN1	O00255-1.4	G168H	Pathogenic	0.928
MEN1	O00255-1.4	G168I	Pathogenic	0.997
MEN1	O00255-1.4	G168K	Pathogenic	0.995
MEN1	O00255-1.4	G168L	Pathogenic	0.997
MEN1	O00255-1.4	G168M	Pathogenic	0.992
MEN1	O00255-1.4	G168N	Pathogenic	0.825
MEN1	O00255-1.4	G168P	Pathogenic	0.804
MEN1	O00255-1.4	G168Q	Pathogenic	0.917
MEN1	O00255-1.4	G168R	Pathogenic	0.998
MEN1	O00255-1.4	G168S	Neutral	0.253
MEN1	O00255-1.4	G168T	Pathogenic	0.708
MEN1	O00255-1.4	G168V	Pathogenic	0.968
MEN1	O00255-1.4	G168W	Pathogenic	1.0
MEN1	O00255-1.4	G168Y	Pathogenic	0.997
MEN1	O00255-1.4	A169C	Pathogenic	0.628
MEN1	O00255-1.4	A169D	Pathogenic	0.842
MEN1	O00255-1.4	A169E	Pathogenic	0.94
MEN1	O00255-1.4	A169F	Pathogenic	0.996
MEN1	O00255-1.4	A169G	Neutral	0.483
MEN1	O00255-1.4	A169H	Pathogenic	0.903
MEN1	O00255-1.4	A169I	Pathogenic	0.991
MEN1	O00255-1.4	A169K	Pathogenic	0.995
MEN1	O00255-1.4	A169L	Pathogenic	0.99
MEN1	O00255-1.4	A169M	Pathogenic	0.979
MEN1	O00255-1.4	A169N	Pathogenic	0.855
MEN1	O00255-1.4	A169P	Pathogenic	0.612
MEN1	O00255-1.4	A169Q	Pathogenic	0.92
MEN1	O00255-1.4	A169R	Pathogenic	0.998
MEN1	O00255-1.4	A169S	Neutral	0.261
MEN1	O00255-1.4	A169T	Pathogenic	0.509
MEN1	O00255-1.4	A169V	Pathogenic	0.911
MEN1	O00255-1.4	A169W	Pathogenic	1.0
MEN1	O00255-1.4	A169Y	Pathogenic	0.991
MEN1	O00255-1.4	C170A	Pathogenic	0.999
MEN1	O00255-1.4	C170D	Pathogenic	1.0
MEN1	O00255-1.4	C170E	Pathogenic	1.0
MEN1	O00255-1.4	C170F	Pathogenic	1.0
MEN1	O00255-1.4	C170G	Pathogenic	1.0
MEN1	O00255-1.4	C170H	Pathogenic	1.0
MEN1	O00255-1.4	C170I	Pathogenic	1.0
MEN1	O00255-1.4	C170K	Pathogenic	1.0
MEN1	O00255-1.4	C170L	Pathogenic	1.0
MEN1	O00255-1.4	C170M	Pathogenic	1.0
MEN1	O00255-1.4	C170N	Pathogenic	1.0
MEN1	O00255-1.4	C170P	Pathogenic	0.995
MEN1	O00255-1.4	C170Q	Pathogenic	1.0
MEN1	O00255-1.4	C170R	Pathogenic	1.0
MEN1	O00255-1.4	C170S	Pathogenic	0.999
MEN1	O00255-1.4	C170T	Pathogenic	0.998
MEN1	O00255-1.4	C170V	Pathogenic	0.998
MEN1	O00255-1.4	C170W	Pathogenic	1.0
MEN1	O00255-1.4	C170Y	Pathogenic	1.0
MEN1	O00255-1.4	Q171A	Pathogenic	0.998
MEN1	O00255-1.4	Q171C	Pathogenic	0.998
MEN1	O00255-1.4	Q171D	Pathogenic	0.99
MEN1	O00255-1.4	Q171E	Pathogenic	0.95
MEN1	O00255-1.4	Q171F	Pathogenic	0.999
MEN1	O00255-1.4	Q171G	Pathogenic	0.999
MEN1	O00255-1.4	Q171H	Pathogenic	0.947
MEN1	O00255-1.4	Q171I	Pathogenic	0.998
MEN1	O00255-1.4	Q171K	Pathogenic	0.992
MEN1	O00255-1.4	Q171L	Pathogenic	0.998
MEN1	O00255-1.4	Q171M	Pathogenic	0.994
MEN1	O00255-1.4	Q171N	Pathogenic	0.982
MEN1	O00255-1.4	Q171P	Pathogenic	0.995
MEN1	O00255-1.4	Q171R	Pathogenic	0.997
MEN1	O00255-1.4	Q171S	Pathogenic	0.995
MEN1	O00255-1.4	Q171T	Pathogenic	0.988
MEN1	O00255-1.4	Q171V	Pathogenic	0.994
MEN1	O00255-1.4	Q171W	Pathogenic	1.0
MEN1	O00255-1.4	Q171Y	Pathogenic	0.998
MEN1	O00255-1.4	A172C	Neutral	0.076
MEN1	O00255-1.4	A172D	Neutral	0.205
MEN1	O00255-1.4	A172E	Neutral	0.43
MEN1	O00255-1.4	A172F	Pathogenic	0.93
MEN1	O00255-1.4	A172G	Neutral	0.043
MEN1	O00255-1.4	A172H	Neutral	0.31
MEN1	O00255-1.4	A172I	Pathogenic	0.849
MEN1	O00255-1.4	A172K	Pathogenic	0.903
MEN1	O00255-1.4	A172L	Pathogenic	0.827
MEN1	O00255-1.4	A172M	Pathogenic	0.69
MEN1	O00255-1.4	A172N	Neutral	0.222
MEN1	O00255-1.4	A172P	Neutral	0.071
MEN1	O00255-1.4	A172Q	Neutral	0.357
MEN1	O00255-1.4	A172R	Pathogenic	0.962
MEN1	O00255-1.4	A172S	Neutral	0.017
MEN1	O00255-1.4	A172T	Neutral	0.048
MEN1	O00255-1.4	A172V	Neutral	0.331
MEN1	O00255-1.4	A172W	Pathogenic	0.996
MEN1	O00255-1.4	A172Y	Pathogenic	0.844
MEN1	O00255-1.4	L173A	Pathogenic	0.999
MEN1	O00255-1.4	L173C	Pathogenic	0.989
MEN1	O00255-1.4	L173D	Pathogenic	0.999
MEN1	O00255-1.4	L173E	Pathogenic	0.996
MEN1	O00255-1.4	L173F	Pathogenic	0.799
MEN1	O00255-1.4	L173G	Pathogenic	1.0
MEN1	O00255-1.4	L173H	Pathogenic	0.973
MEN1	O00255-1.4	L173I	Pathogenic	0.613
MEN1	O00255-1.4	L173K	Pathogenic	0.997
MEN1	O00255-1.4	L173M	Pathogenic	0.742
MEN1	O00255-1.4	L173N	Pathogenic	0.998
MEN1	O00255-1.4	L173P	Pathogenic	0.991
MEN1	O00255-1.4	L173Q	Pathogenic	0.988
MEN1	O00255-1.4	L173R	Pathogenic	0.999
MEN1	O00255-1.4	L173S	Pathogenic	0.999
MEN1	O00255-1.4	L173T	Pathogenic	0.994
MEN1	O00255-1.4	L173V	Pathogenic	0.928
MEN1	O00255-1.4	L173W	Pathogenic	0.987
MEN1	O00255-1.4	L173Y	Pathogenic	0.95
MEN1	O00255-1.4	G174A	Pathogenic	0.907
MEN1	O00255-1.4	G174C	Pathogenic	0.993
MEN1	O00255-1.4	G174D	Pathogenic	0.992
MEN1	O00255-1.4	G174E	Pathogenic	0.998
MEN1	O00255-1.4	G174F	Pathogenic	1.0
MEN1	O00255-1.4	G174H	Pathogenic	0.997
MEN1	O00255-1.4	G174I	Pathogenic	1.0
MEN1	O00255-1.4	G174K	Pathogenic	1.0
MEN1	O00255-1.4	G174L	Pathogenic	1.0
MEN1	O00255-1.4	G174M	Pathogenic	1.0
MEN1	O00255-1.4	G174N	Pathogenic	0.993
MEN1	O00255-1.4	G174P	Pathogenic	0.992
MEN1	O00255-1.4	G174Q	Pathogenic	0.997
MEN1	O00255-1.4	G174R	Pathogenic	1.0
MEN1	O00255-1.4	G174S	Pathogenic	0.908
MEN1	O00255-1.4	G174T	Pathogenic	0.986
MEN1	O00255-1.4	G174V	Pathogenic	0.999
MEN1	O00255-1.4	G174W	Pathogenic	1.0
MEN1	O00255-1.4	G174Y	Pathogenic	1.0
MEN1	O00255-1.4	L175A	Pathogenic	0.926
MEN1	O00255-1.4	L175C	Pathogenic	0.505
MEN1	O00255-1.4	L175D	Pathogenic	0.935
MEN1	O00255-1.4	L175E	Pathogenic	0.741
MEN1	O00255-1.4	L175F	Neutral	0.044
MEN1	O00255-1.4	L175G	Pathogenic	0.99
MEN1	O00255-1.4	L175H	Neutral	0.295
MEN1	O00255-1.4	L175I	Neutral	0.018
MEN1	O00255-1.4	L175K	Pathogenic	0.779
MEN1	O00255-1.4	L175M	Neutral	0.032
MEN1	O00255-1.4	L175N	Pathogenic	0.877
MEN1	O00255-1.4	L175P	Pathogenic	0.567
MEN1	O00255-1.4	L175Q	Neutral	0.485
MEN1	O00255-1.4	L175R	Pathogenic	0.905
MEN1	O00255-1.4	L175S	Pathogenic	0.937
MEN1	O00255-1.4	L175T	Pathogenic	0.663
MEN1	O00255-1.4	L175V	Neutral	0.13
MEN1	O00255-1.4	L175W	Neutral	0.47
MEN1	O00255-1.4	L175Y	Neutral	0.181
MEN1	O00255-1.4	R176A	Pathogenic	0.868
MEN1	O00255-1.4	R176C	Pathogenic	0.843
MEN1	O00255-1.4	R176D	Neutral	0.168
MEN1	O00255-1.4	R176E	Neutral	0.055
MEN1	O00255-1.4	R176F	Neutral	0.338
MEN1	O00255-1.4	R176G	Pathogenic	0.946
MEN1	O00255-1.4	R176H	Neutral	0.093
MEN1	O00255-1.4	R176I	Pathogenic	0.543
MEN1	O00255-1.4	R176K	Neutral	0.004
MEN1	O00255-1.4	R176L	Neutral	0.486
MEN1	O00255-1.4	R176M	Neutral	0.294
MEN1	O00255-1.4	R176N	Neutral	0.14
MEN1	O00255-1.4	R176P	Pathogenic	0.709
MEN1	O00255-1.4	R176Q	Neutral	0.069
MEN1	O00255-1.4	R176S	Pathogenic	0.706
MEN1	O00255-1.4	R176T	Neutral	0.464
MEN1	O00255-1.4	R176V	Pathogenic	0.655
MEN1	O00255-1.4	R176W	Pathogenic	0.556
MEN1	O00255-1.4	R176Y	Neutral	0.074
MEN1	O00255-1.4	D177A	Pathogenic	0.994
MEN1	O00255-1.4	D177C	Pathogenic	0.992
MEN1	O00255-1.4	D177E	Pathogenic	0.949
MEN1	O00255-1.4	D177F	Pathogenic	1.0
MEN1	O00255-1.4	D177G	Pathogenic	0.998
MEN1	O00255-1.4	D177H	Pathogenic	0.993
MEN1	O00255-1.4	D177I	Pathogenic	1.0
MEN1	O00255-1.4	D177K	Pathogenic	0.994
MEN1	O00255-1.4	D177L	Pathogenic	1.0
MEN1	O00255-1.4	D177M	Pathogenic	0.999
MEN1	O00255-1.4	D177N	Pathogenic	0.888
MEN1	O00255-1.4	D177P	Pathogenic	0.983
MEN1	O00255-1.4	D177Q	Pathogenic	0.984
MEN1	O00255-1.4	D177R	Pathogenic	0.998
MEN1	O00255-1.4	D177S	Pathogenic	0.982
MEN1	O00255-1.4	D177T	Pathogenic	0.966
MEN1	O00255-1.4	D177V	Pathogenic	0.997
MEN1	O00255-1.4	D177W	Pathogenic	1.0
MEN1	O00255-1.4	D177Y	Pathogenic	1.0
MEN1	O00255-1.4	V178A	Pathogenic	0.994
MEN1	O00255-1.4	V178C	Pathogenic	0.936
MEN1	O00255-1.4	V178D	Pathogenic	0.995
MEN1	O00255-1.4	V178E	Pathogenic	0.986
MEN1	O00255-1.4	V178F	Pathogenic	0.983
MEN1	O00255-1.4	V178G	Pathogenic	0.999
MEN1	O00255-1.4	V178H	Pathogenic	0.977
MEN1	O00255-1.4	V178I	Pathogenic	0.954
MEN1	O00255-1.4	V178K	Pathogenic	0.999
MEN1	O00255-1.4	V178L	Pathogenic	0.951
MEN1	O00255-1.4	V178M	Pathogenic	0.901
MEN1	O00255-1.4	V178N	Pathogenic	0.99
MEN1	O00255-1.4	V178P	Pathogenic	0.947
MEN1	O00255-1.4	V178Q	Pathogenic	0.981
MEN1	O00255-1.4	V178R	Pathogenic	1.0
MEN1	O00255-1.4	V178S	Pathogenic	0.995
MEN1	O00255-1.4	V178T	Pathogenic	0.964
MEN1	O00255-1.4	V178W	Pathogenic	0.999
MEN1	O00255-1.4	V178Y	Pathogenic	0.982
MEN1	O00255-1.4	H179A	Pathogenic	0.999
MEN1	O00255-1.4	H179C	Pathogenic	0.999
MEN1	O00255-1.4	H179D	Pathogenic	0.999
MEN1	O00255-1.4	H179E	Pathogenic	0.993
MEN1	O00255-1.4	H179F	Pathogenic	0.999
MEN1	O00255-1.4	H179G	Pathogenic	1.0
MEN1	O00255-1.4	H179I	Pathogenic	0.998
MEN1	O00255-1.4	H179K	Pathogenic	0.998
MEN1	O00255-1.4	H179L	Pathogenic	0.998
MEN1	O00255-1.4	H179M	Pathogenic	0.995
MEN1	O00255-1.4	H179N	Pathogenic	0.997
MEN1	O00255-1.4	H179P	Pathogenic	0.998
MEN1	O00255-1.4	H179Q	Pathogenic	0.979
MEN1	O00255-1.4	H179R	Pathogenic	0.999
MEN1	O00255-1.4	H179S	Pathogenic	0.999
MEN1	O00255-1.4	H179T	Pathogenic	0.994
MEN1	O00255-1.4	H179V	Pathogenic	0.997
MEN1	O00255-1.4	H179W	Pathogenic	1.0
MEN1	O00255-1.4	H179Y	Pathogenic	0.997
MEN1	O00255-1.4	L180A	Pathogenic	0.999
MEN1	O00255-1.4	L180C	Pathogenic	0.988
MEN1	O00255-1.4	L180D	Pathogenic	0.999
MEN1	O00255-1.4	L180E	Pathogenic	0.996
MEN1	O00255-1.4	L180F	Pathogenic	0.786
MEN1	O00255-1.4	L180G	Pathogenic	1.0
MEN1	O00255-1.4	L180H	Pathogenic	0.971
MEN1	O00255-1.4	L180I	Pathogenic	0.595
MEN1	O00255-1.4	L180K	Pathogenic	0.996
MEN1	O00255-1.4	L180M	Pathogenic	0.727
MEN1	O00255-1.4	L180N	Pathogenic	0.998
MEN1	O00255-1.4	L180P	Pathogenic	0.991
MEN1	O00255-1.4	L180Q	Pathogenic	0.987
MEN1	O00255-1.4	L180R	Pathogenic	0.999
MEN1	O00255-1.4	L180S	Pathogenic	0.999
MEN1	O00255-1.4	L180T	Pathogenic	0.994
MEN1	O00255-1.4	L180V	Pathogenic	0.923
MEN1	O00255-1.4	L180W	Pathogenic	0.986
MEN1	O00255-1.4	L180Y	Pathogenic	0.946
MEN1	O00255-1.4	A181C	Pathogenic	0.925
MEN1	O00255-1.4	A181D	Pathogenic	0.975
MEN1	O00255-1.4	A181E	Pathogenic	0.991
MEN1	O00255-1.4	A181F	Pathogenic	0.999
MEN1	O00255-1.4	A181G	Pathogenic	0.872
MEN1	O00255-1.4	A181H	Pathogenic	0.985
MEN1	O00255-1.4	A181I	Pathogenic	0.999
MEN1	O00255-1.4	A181K	Pathogenic	0.999
MEN1	O00255-1.4	A181L	Pathogenic	0.999
MEN1	O00255-1.4	A181M	Pathogenic	0.997
MEN1	O00255-1.4	A181N	Pathogenic	0.977
MEN1	O00255-1.4	A181P	Pathogenic	0.92
MEN1	O00255-1.4	A181Q	Pathogenic	0.988
MEN1	O00255-1.4	A181R	Pathogenic	1.0
MEN1	O00255-1.4	A181S	Pathogenic	0.72
MEN1	O00255-1.4	A181T	Pathogenic	0.883
MEN1	O00255-1.4	A181V	Pathogenic	0.987
MEN1	O00255-1.4	A181W	Pathogenic	1.0
MEN1	O00255-1.4	A181Y	Pathogenic	0.999
MEN1	O00255-1.4	L182A	Pathogenic	0.99
MEN1	O00255-1.4	L182C	Pathogenic	0.889
MEN1	O00255-1.4	L182D	Pathogenic	0.991
MEN1	O00255-1.4	L182E	Pathogenic	0.957
MEN1	O00255-1.4	L182F	Neutral	0.265
MEN1	O00255-1.4	L182G	Pathogenic	0.999
MEN1	O00255-1.4	L182H	Pathogenic	0.767
MEN1	O00255-1.4	L182I	Neutral	0.126
MEN1	O00255-1.4	L182K	Pathogenic	0.965
MEN1	O00255-1.4	L182M	Neutral	0.207
MEN1	O00255-1.4	L182N	Pathogenic	0.982
MEN1	O00255-1.4	L182P	Pathogenic	0.911
MEN1	O00255-1.4	L182Q	Pathogenic	0.881
MEN1	O00255-1.4	L182R	Pathogenic	0.987
MEN1	O00255-1.4	L182S	Pathogenic	0.992
MEN1	O00255-1.4	L182T	Pathogenic	0.939
MEN1	O00255-1.4	L182V	Pathogenic	0.54
MEN1	O00255-1.4	L182W	Pathogenic	0.875
MEN1	O00255-1.4	L182Y	Pathogenic	0.634
MEN1	O00255-1.4	S183A	Pathogenic	0.768
MEN1	O00255-1.4	S183C	Pathogenic	0.949
MEN1	O00255-1.4	S183D	Pathogenic	0.942
MEN1	O00255-1.4	S183E	Pathogenic	0.98
MEN1	O00255-1.4	S183F	Pathogenic	1.0
MEN1	O00255-1.4	S183G	Pathogenic	0.898
MEN1	O00255-1.4	S183H	Pathogenic	0.981
MEN1	O00255-1.4	S183I	Pathogenic	0.999
MEN1	O00255-1.4	S183K	Pathogenic	0.998
MEN1	O00255-1.4	S183L	Pathogenic	0.999
MEN1	O00255-1.4	S183M	Pathogenic	0.998
MEN1	O00255-1.4	S183N	Pathogenic	0.944
MEN1	O00255-1.4	S183P	Pathogenic	0.943
MEN1	O00255-1.4	S183Q	Pathogenic	0.974
MEN1	O00255-1.4	S183R	Pathogenic	0.999
MEN1	O00255-1.4	S183T	Pathogenic	0.896
MEN1	O00255-1.4	S183V	Pathogenic	0.992
MEN1	O00255-1.4	S183W	Pathogenic	1.0
MEN1	O00255-1.4	S183Y	Pathogenic	0.999
MEN1	O00255-1.4	E184A	Pathogenic	0.996
MEN1	O00255-1.4	E184C	Pathogenic	0.995
MEN1	O00255-1.4	E184D	Pathogenic	0.894
MEN1	O00255-1.4	E184F	Pathogenic	0.999
MEN1	O00255-1.4	E184G	Pathogenic	0.998
MEN1	O00255-1.4	E184H	Pathogenic	0.932
MEN1	O00255-1.4	E184I	Pathogenic	0.997
MEN1	O00255-1.4	E184K	Pathogenic	0.959
MEN1	O00255-1.4	E184L	Pathogenic	0.997
MEN1	O00255-1.4	E184M	Pathogenic	0.993
MEN1	O00255-1.4	E184N	Pathogenic	0.849
MEN1	O00255-1.4	E184P	Pathogenic	0.988
MEN1	O00255-1.4	E184Q	Pathogenic	0.836
MEN1	O00255-1.4	E184R	Pathogenic	0.985
MEN1	O00255-1.4	E184S	Pathogenic	0.987
MEN1	O00255-1.4	E184T	Pathogenic	0.968
MEN1	O00255-1.4	E184V	Pathogenic	0.984
MEN1	O00255-1.4	E184W	Pathogenic	1.0
MEN1	O00255-1.4	E184Y	Pathogenic	0.997
MEN1	O00255-1.4	D185A	Pathogenic	0.994
MEN1	O00255-1.4	D185C	Pathogenic	0.993
MEN1	O00255-1.4	D185E	Pathogenic	0.95
MEN1	O00255-1.4	D185F	Pathogenic	1.0
MEN1	O00255-1.4	D185G	Pathogenic	0.998
MEN1	O00255-1.4	D185H	Pathogenic	0.994
MEN1	O00255-1.4	D185I	Pathogenic	1.0
MEN1	O00255-1.4	D185K	Pathogenic	0.995
MEN1	O00255-1.4	D185L	Pathogenic	1.0
MEN1	O00255-1.4	D185M	Pathogenic	0.999
MEN1	O00255-1.4	D185N	Pathogenic	0.891
MEN1	O00255-1.4	D185P	Pathogenic	0.983
MEN1	O00255-1.4	D185Q	Pathogenic	0.984
MEN1	O00255-1.4	D185R	Pathogenic	0.998
MEN1	O00255-1.4	D185S	Pathogenic	0.983
MEN1	O00255-1.4	D185T	Pathogenic	0.967
MEN1	O00255-1.4	D185V	Pathogenic	0.997
MEN1	O00255-1.4	D185W	Pathogenic	1.0
MEN1	O00255-1.4	D185Y	Pathogenic	1.0
MEN1	O00255-1.4	H186A	Pathogenic	0.999
MEN1	O00255-1.4	H186C	Pathogenic	0.999
MEN1	O00255-1.4	H186D	Pathogenic	0.999
MEN1	O00255-1.4	H186E	Pathogenic	0.995
MEN1	O00255-1.4	H186F	Pathogenic	0.999
MEN1	O00255-1.4	H186G	Pathogenic	1.0
MEN1	O00255-1.4	H186I	Pathogenic	0.999
MEN1	O00255-1.4	H186K	Pathogenic	0.998
MEN1	O00255-1.4	H186L	Pathogenic	0.998
MEN1	O00255-1.4	H186M	Pathogenic	0.996
MEN1	O00255-1.4	H186N	Pathogenic	0.998
MEN1	O00255-1.4	H186P	Pathogenic	0.998
MEN1	O00255-1.4	H186Q	Pathogenic	0.985
MEN1	O00255-1.4	H186R	Pathogenic	0.999
MEN1	O00255-1.4	H186S	Pathogenic	0.999
MEN1	O00255-1.4	H186T	Pathogenic	0.996
MEN1	O00255-1.4	H186V	Pathogenic	0.998
MEN1	O00255-1.4	H186W	Pathogenic	1.0
MEN1	O00255-1.4	H186Y	Pathogenic	0.998
MEN1	O00255-1.4	A187C	Pathogenic	0.851
MEN1	O00255-1.4	A187D	Pathogenic	0.947
MEN1	O00255-1.4	A187E	Pathogenic	0.981
MEN1	O00255-1.4	A187F	Pathogenic	0.999
MEN1	O00255-1.4	A187G	Pathogenic	0.759
MEN1	O00255-1.4	A187H	Pathogenic	0.969
MEN1	O00255-1.4	A187I	Pathogenic	0.997
MEN1	O00255-1.4	A187K	Pathogenic	0.998
MEN1	O00255-1.4	A187L	Pathogenic	0.997
MEN1	O00255-1.4	A187M	Pathogenic	0.994
MEN1	O00255-1.4	A187N	Pathogenic	0.952
MEN1	O00255-1.4	A187P	Pathogenic	0.842
MEN1	O00255-1.4	A187Q	Pathogenic	0.975
MEN1	O00255-1.4	A187R	Pathogenic	0.999
MEN1	O00255-1.4	A187S	Pathogenic	0.543
MEN1	O00255-1.4	A187T	Pathogenic	0.778
MEN1	O00255-1.4	A187V	Pathogenic	0.972
MEN1	O00255-1.4	A187W	Pathogenic	1.0
MEN1	O00255-1.4	A187Y	Pathogenic	0.997
MEN1	O00255-1.4	W188A	Pathogenic	1.0
MEN1	O00255-1.4	W188C	Pathogenic	1.0
MEN1	O00255-1.4	W188D	Pathogenic	1.0
MEN1	O00255-1.4	W188E	Pathogenic	1.0
MEN1	O00255-1.4	W188F	Pathogenic	0.999
MEN1	O00255-1.4	W188G	Pathogenic	1.0
MEN1	O00255-1.4	W188H	Pathogenic	1.0
MEN1	O00255-1.4	W188I	Pathogenic	1.0
MEN1	O00255-1.4	W188K	Pathogenic	1.0
MEN1	O00255-1.4	W188L	Pathogenic	1.0
MEN1	O00255-1.4	W188M	Pathogenic	1.0
MEN1	O00255-1.4	W188N	Pathogenic	1.0
MEN1	O00255-1.4	W188P	Pathogenic	1.0
MEN1	O00255-1.4	W188Q	Pathogenic	1.0
MEN1	O00255-1.4	W188R	Pathogenic	1.0
MEN1	O00255-1.4	W188S	Pathogenic	1.0
MEN1	O00255-1.4	W188T	Pathogenic	1.0
MEN1	O00255-1.4	W188V	Pathogenic	1.0
MEN1	O00255-1.4	W188Y	Pathogenic	1.0
MEN1	O00255-1.4	V189A	Pathogenic	0.992
MEN1	O00255-1.4	V189C	Pathogenic	0.916
MEN1	O00255-1.4	V189D	Pathogenic	0.993
MEN1	O00255-1.4	V189E	Pathogenic	0.981
MEN1	O00255-1.4	V189F	Pathogenic	0.977
MEN1	O00255-1.4	V189G	Pathogenic	0.999
MEN1	O00255-1.4	V189H	Pathogenic	0.969
MEN1	O00255-1.4	V189I	Pathogenic	0.938
MEN1	O00255-1.4	V189K	Pathogenic	0.998
MEN1	O00255-1.4	V189L	Pathogenic	0.935
MEN1	O00255-1.4	V189M	Pathogenic	0.871
MEN1	O00255-1.4	V189N	Pathogenic	0.987
MEN1	O00255-1.4	V189P	Pathogenic	0.929
MEN1	O00255-1.4	V189Q	Pathogenic	0.975
MEN1	O00255-1.4	V189R	Pathogenic	0.999
MEN1	O00255-1.4	V189S	Pathogenic	0.994
MEN1	O00255-1.4	V189T	Pathogenic	0.952
MEN1	O00255-1.4	V189W	Pathogenic	0.999
MEN1	O00255-1.4	V189Y	Pathogenic	0.976
MEN1	O00255-1.4	V190A	Pathogenic	0.907
MEN1	O00255-1.4	V190C	Neutral	0.455
MEN1	O00255-1.4	V190D	Pathogenic	0.917
MEN1	O00255-1.4	V190E	Pathogenic	0.8
MEN1	O00255-1.4	V190F	Pathogenic	0.766
MEN1	O00255-1.4	V190G	Pathogenic	0.988
MEN1	O00255-1.4	V190H	Pathogenic	0.705
MEN1	O00255-1.4	V190I	Pathogenic	0.537
MEN1	O00255-1.4	V190K	Pathogenic	0.98
MEN1	O00255-1.4	V190L	Pathogenic	0.526
MEN1	O00255-1.4	V190M	Neutral	0.341
MEN1	O00255-1.4	V190N	Pathogenic	0.853
MEN1	O00255-1.4	V190P	Pathogenic	0.502
MEN1	O00255-1.4	V190Q	Pathogenic	0.747
MEN1	O00255-1.4	V190R	Pathogenic	0.993
MEN1	O00255-1.4	V190S	Pathogenic	0.924
MEN1	O00255-1.4	V190T	Pathogenic	0.602
MEN1	O00255-1.4	V190W	Pathogenic	0.984
MEN1	O00255-1.4	V190Y	Pathogenic	0.755
MEN1	O00255-1.4	F191A	Pathogenic	1.0
MEN1	O00255-1.4	F191C	Pathogenic	0.998
MEN1	O00255-1.4	F191D	Pathogenic	1.0
MEN1	O00255-1.4	F191E	Pathogenic	0.999
MEN1	O00255-1.4	F191G	Pathogenic	1.0
MEN1	O00255-1.4	F191H	Pathogenic	0.993
MEN1	O00255-1.4	F191I	Pathogenic	0.852
MEN1	O00255-1.4	F191K	Pathogenic	0.996
MEN1	O00255-1.4	F191L	Pathogenic	0.866
MEN1	O00255-1.4	F191M	Pathogenic	0.933
MEN1	O00255-1.4	F191N	Pathogenic	1.0
MEN1	O00255-1.4	F191P	Pathogenic	0.998
MEN1	O00255-1.4	F191Q	Pathogenic	0.997
MEN1	O00255-1.4	F191R	Pathogenic	0.999
MEN1	O00255-1.4	F191S	Pathogenic	1.0
MEN1	O00255-1.4	F191T	Pathogenic	0.999
MEN1	O00255-1.4	F191V	Pathogenic	0.984
MEN1	O00255-1.4	F191W	Pathogenic	0.975
MEN1	O00255-1.4	F191Y	Pathogenic	0.925
MEN1	O00255-1.4	G192A	Pathogenic	0.874
MEN1	O00255-1.4	G192C	Pathogenic	0.99
MEN1	O00255-1.4	G192D	Pathogenic	0.989
MEN1	O00255-1.4	G192E	Pathogenic	0.997
MEN1	O00255-1.4	G192F	Pathogenic	1.0
MEN1	O00255-1.4	G192H	Pathogenic	0.996
MEN1	O00255-1.4	G192I	Pathogenic	1.0
MEN1	O00255-1.4	G192K	Pathogenic	1.0
MEN1	O00255-1.4	G192L	Pathogenic	1.0
MEN1	O00255-1.4	G192M	Pathogenic	1.0
MEN1	O00255-1.4	G192N	Pathogenic	0.99
MEN1	O00255-1.4	G192P	Pathogenic	0.988
MEN1	O00255-1.4	G192Q	Pathogenic	0.996
MEN1	O00255-1.4	G192R	Pathogenic	1.0
MEN1	O00255-1.4	G192S	Pathogenic	0.875
MEN1	O00255-1.4	G192T	Pathogenic	0.98
MEN1	O00255-1.4	G192V	Pathogenic	0.998
MEN1	O00255-1.4	G192W	Pathogenic	1.0
MEN1	O00255-1.4	G192Y	Pathogenic	1.0
MEN1	O00255-1.4	P193A	Neutral	0.042
MEN1	O00255-1.4	P193C	Neutral	0.009
MEN1	O00255-1.4	P193D	Neutral	0.047
MEN1	O00255-1.4	P193E	Neutral	0.131
MEN1	O00255-1.4	P193F	Neutral	0.443
MEN1	O00255-1.4	P193G	Neutral	0.241
MEN1	O00255-1.4	P193H	Neutral	0.083
MEN1	O00255-1.4	P193I	Neutral	0.252
MEN1	O00255-1.4	P193K	Pathogenic	0.651
MEN1	O00255-1.4	P193L	Neutral	0.222
MEN1	O00255-1.4	P193M	Neutral	0.111
MEN1	O00255-1.4	P193N	Neutral	0.054
MEN1	O00255-1.4	P193Q	Neutral	0.1
MEN1	O00255-1.4	P193R	Pathogenic	0.843
MEN1	O00255-1.4	P193S	Neutral	0.047
MEN1	O00255-1.4	P193T	Neutral	0.011
MEN1	O00255-1.4	P193V	Neutral	0.029
MEN1	O00255-1.4	P193W	Pathogenic	0.932
MEN1	O00255-1.4	P193Y	Neutral	0.234
MEN1	O00255-1.4	N194A	Pathogenic	0.621
MEN1	O00255-1.4	N194C	Pathogenic	0.557
MEN1	O00255-1.4	N194D	Neutral	0.064
MEN1	O00255-1.4	N194E	Neutral	0.096
MEN1	O00255-1.4	N194F	Pathogenic	0.976
MEN1	O00255-1.4	N194G	Pathogenic	0.784
MEN1	O00255-1.4	N194H	Neutral	0.378
MEN1	O00255-1.4	N194I	Pathogenic	0.948
MEN1	O00255-1.4	N194K	Pathogenic	0.568
MEN1	O00255-1.4	N194L	Pathogenic	0.939
MEN1	O00255-1.4	N194M	Pathogenic	0.872
MEN1	O00255-1.4	N194P	Neutral	0.364
MEN1	O00255-1.4	N194Q	Neutral	0.213
MEN1	O00255-1.4	N194R	Pathogenic	0.781
MEN1	O00255-1.4	N194S	Neutral	0.333
MEN1	O00255-1.4	N194T	Neutral	0.161
MEN1	O00255-1.4	N194V	Pathogenic	0.63
MEN1	O00255-1.4	N194W	Pathogenic	0.999
MEN1	O00255-1.4	N194Y	Pathogenic	0.94
MEN1	O00255-1.4	G195A	Pathogenic	0.733
MEN1	O00255-1.4	G195C	Pathogenic	0.976
MEN1	O00255-1.4	G195D	Pathogenic	0.974
MEN1	O00255-1.4	G195E	Pathogenic	0.992
MEN1	O00255-1.4	G195F	Pathogenic	1.0
MEN1	O00255-1.4	G195H	Pathogenic	0.991
MEN1	O00255-1.4	G195I	Pathogenic	1.0
MEN1	O00255-1.4	G195K	Pathogenic	0.999
MEN1	O00255-1.4	G195L	Pathogenic	1.0
MEN1	O00255-1.4	G195M	Pathogenic	0.999
MEN1	O00255-1.4	G195N	Pathogenic	0.975
MEN1	O00255-1.4	G195P	Pathogenic	0.971
MEN1	O00255-1.4	G195Q	Pathogenic	0.989
MEN1	O00255-1.4	G195R	Pathogenic	1.0
MEN1	O00255-1.4	G195S	Pathogenic	0.735
MEN1	O00255-1.4	G195T	Pathogenic	0.952
MEN1	O00255-1.4	G195V	Pathogenic	0.996
MEN1	O00255-1.4	G195W	Pathogenic	1.0
MEN1	O00255-1.4	G195Y	Pathogenic	1.0
MEN1	O00255-1.4	E196A	Pathogenic	0.565
MEN1	O00255-1.4	E196C	Pathogenic	0.53
MEN1	O00255-1.4	E196D	Neutral	0.046
MEN1	O00255-1.4	E196F	Pathogenic	0.831
MEN1	O00255-1.4	E196G	Pathogenic	0.776
MEN1	O00255-1.4	E196H	Neutral	0.073
MEN1	O00255-1.4	E196I	Pathogenic	0.688
MEN1	O00255-1.4	E196K	Neutral	0.118
MEN1	O00255-1.4	E196L	Pathogenic	0.652
MEN1	O00255-1.4	E196M	Neutral	0.451
MEN1	O00255-1.4	E196N	Neutral	0.031
MEN1	O00255-1.4	E196P	Neutral	0.312
MEN1	O00255-1.4	E196Q	Neutral	0.028
MEN1	O00255-1.4	E196R	Neutral	0.277
MEN1	O00255-1.4	E196S	Neutral	0.309
MEN1	O00255-1.4	E196T	Neutral	0.147
MEN1	O00255-1.4	E196V	Neutral	0.261
MEN1	O00255-1.4	E196W	Pathogenic	0.988
MEN1	O00255-1.4	E196Y	Pathogenic	0.654
MEN1	O00255-1.4	Q197A	Pathogenic	0.693
MEN1	O00255-1.4	Q197C	Pathogenic	0.648
MEN1	O00255-1.4	Q197D	Neutral	0.269
MEN1	O00255-1.4	Q197E	Neutral	0.064
MEN1	O00255-1.4	Q197F	Pathogenic	0.802
MEN1	O00255-1.4	Q197G	Pathogenic	0.858
MEN1	O00255-1.4	Q197H	Neutral	0.061
MEN1	O00255-1.4	Q197I	Pathogenic	0.645
MEN1	O00255-1.4	Q197K	Neutral	0.299
MEN1	O00255-1.4	Q197L	Pathogenic	0.592
MEN1	O00255-1.4	Q197M	Neutral	0.375
MEN1	O00255-1.4	Q197N	Neutral	0.161
MEN1	O00255-1.4	Q197P	Neutral	0.441
MEN1	O00255-1.4	Q197R	Pathogenic	0.535
MEN1	O00255-1.4	Q197S	Neutral	0.437
MEN1	O00255-1.4	Q197T	Neutral	0.23
MEN1	O00255-1.4	Q197V	Neutral	0.38
MEN1	O00255-1.4	Q197W	Pathogenic	0.985
MEN1	O00255-1.4	Q197Y	Pathogenic	0.594
MEN1	O00255-1.4	T198A	Pathogenic	0.97
MEN1	O00255-1.4	T198C	Pathogenic	0.962
MEN1	O00255-1.4	T198D	Pathogenic	0.966
MEN1	O00255-1.4	T198E	Pathogenic	0.985
MEN1	O00255-1.4	T198F	Pathogenic	0.999
MEN1	O00255-1.4	T198G	Pathogenic	0.995
MEN1	O00255-1.4	T198H	Pathogenic	0.975
MEN1	O00255-1.4	T198I	Pathogenic	0.998
MEN1	O00255-1.4	T198K	Pathogenic	0.999
MEN1	O00255-1.4	T198L	Pathogenic	0.998
MEN1	O00255-1.4	T198M	Pathogenic	0.996
MEN1	O00255-1.4	T198N	Pathogenic	0.956
MEN1	O00255-1.4	T198P	Pathogenic	0.924
MEN1	O00255-1.4	T198Q	Pathogenic	0.979
MEN1	O00255-1.4	T198R	Pathogenic	1.0
MEN1	O00255-1.4	T198S	Pathogenic	0.967
MEN1	O00255-1.4	T198V	Pathogenic	0.98
MEN1	O00255-1.4	T198W	Pathogenic	1.0
MEN1	O00255-1.4	T198Y	Pathogenic	0.998
MEN1	O00255-1.4	A199C	Pathogenic	0.739
MEN1	O00255-1.4	A199D	Pathogenic	0.899
MEN1	O00255-1.4	A199E	Pathogenic	0.963
MEN1	O00255-1.4	A199F	Pathogenic	0.998
MEN1	O00255-1.4	A199G	Pathogenic	0.609
MEN1	O00255-1.4	A199H	Pathogenic	0.939
MEN1	O00255-1.4	A199I	Pathogenic	0.995
MEN1	O00255-1.4	A199K	Pathogenic	0.997
MEN1	O00255-1.4	A199L	Pathogenic	0.994
MEN1	O00255-1.4	A199M	Pathogenic	0.987
MEN1	O00255-1.4	A199N	Pathogenic	0.908
MEN1	O00255-1.4	A199P	Pathogenic	0.725
MEN1	O00255-1.4	A199Q	Pathogenic	0.95
MEN1	O00255-1.4	A199R	Pathogenic	0.999
MEN1	O00255-1.4	A199S	Neutral	0.371
MEN1	O00255-1.4	A199T	Pathogenic	0.634
MEN1	O00255-1.4	A199V	Pathogenic	0.945
MEN1	O00255-1.4	A199W	Pathogenic	1.0
MEN1	O00255-1.4	A199Y	Pathogenic	0.995
MEN1	O00255-1.4	E200A	Pathogenic	0.995
MEN1	O00255-1.4	E200C	Pathogenic	0.994
MEN1	O00255-1.4	E200D	Pathogenic	0.876
MEN1	O00255-1.4	E200F	Pathogenic	0.999
MEN1	O00255-1.4	E200G	Pathogenic	0.998
MEN1	O00255-1.4	E200H	Pathogenic	0.92
MEN1	O00255-1.4	E200I	Pathogenic	0.997
MEN1	O00255-1.4	E200K	Pathogenic	0.951
MEN1	O00255-1.4	E200L	Pathogenic	0.996
MEN1	O00255-1.4	E200M	Pathogenic	0.992
MEN1	O00255-1.4	E200N	Pathogenic	0.824
MEN1	O00255-1.4	E200P	Pathogenic	0.985
MEN1	O00255-1.4	E200Q	Pathogenic	0.81
MEN1	O00255-1.4	E200R	Pathogenic	0.982
MEN1	O00255-1.4	E200S	Pathogenic	0.985
MEN1	O00255-1.4	E200T	Pathogenic	0.962
MEN1	O00255-1.4	E200V	Pathogenic	0.981
MEN1	O00255-1.4	E200W	Pathogenic	1.0
MEN1	O00255-1.4	E200Y	Pathogenic	0.996
MEN1	O00255-1.4	V201A	Pathogenic	0.994
MEN1	O00255-1.4	V201C	Pathogenic	0.935
MEN1	O00255-1.4	V201D	Pathogenic	0.995
MEN1	O00255-1.4	V201E	Pathogenic	0.986
MEN1	O00255-1.4	V201F	Pathogenic	0.983
MEN1	O00255-1.4	V201G	Pathogenic	0.999
MEN1	O00255-1.4	V201H	Pathogenic	0.976
MEN1	O00255-1.4	V201I	Pathogenic	0.952
MEN1	O00255-1.4	V201K	Pathogenic	0.999
MEN1	O00255-1.4	V201L	Pathogenic	0.95
MEN1	O00255-1.4	V201M	Pathogenic	0.899
MEN1	O00255-1.4	V201N	Pathogenic	0.99
MEN1	O00255-1.4	V201P	Pathogenic	0.945
MEN1	O00255-1.4	V201Q	Pathogenic	0.981
MEN1	O00255-1.4	V201R	Pathogenic	1.0
MEN1	O00255-1.4	V201S	Pathogenic	0.995
MEN1	O00255-1.4	V201T	Pathogenic	0.963
MEN1	O00255-1.4	V201W	Pathogenic	0.999
MEN1	O00255-1.4	V201Y	Pathogenic	0.981
MEN1	O00255-1.4	T202A	Pathogenic	0.979
MEN1	O00255-1.4	T202C	Pathogenic	0.973
MEN1	O00255-1.4	T202D	Pathogenic	0.976
MEN1	O00255-1.4	T202E	Pathogenic	0.989
MEN1	O00255-1.4	T202F	Pathogenic	0.999
MEN1	O00255-1.4	T202G	Pathogenic	0.997
MEN1	O00255-1.4	T202H	Pathogenic	0.982
MEN1	O00255-1.4	T202I	Pathogenic	0.999
MEN1	O00255-1.4	T202K	Pathogenic	0.999
MEN1	O00255-1.4	T202L	Pathogenic	0.999
MEN1	O00255-1.4	T202M	Pathogenic	0.997
MEN1	O00255-1.4	T202N	Pathogenic	0.969
MEN1	O00255-1.4	T202P	Pathogenic	0.946
MEN1	O00255-1.4	T202Q	Pathogenic	0.986
MEN1	O00255-1.4	T202R	Pathogenic	1.0
MEN1	O00255-1.4	T202S	Pathogenic	0.977
MEN1	O00255-1.4	T202V	Pathogenic	0.986
MEN1	O00255-1.4	T202W	Pathogenic	1.0
MEN1	O00255-1.4	T202Y	Pathogenic	0.999
MEN1	O00255-1.4	W203A	Pathogenic	1.0
MEN1	O00255-1.4	W203C	Pathogenic	1.0
MEN1	O00255-1.4	W203D	Pathogenic	1.0
MEN1	O00255-1.4	W203E	Pathogenic	1.0
MEN1	O00255-1.4	W203F	Pathogenic	0.999
MEN1	O00255-1.4	W203G	Pathogenic	1.0
MEN1	O00255-1.4	W203H	Pathogenic	1.0
MEN1	O00255-1.4	W203I	Pathogenic	1.0
MEN1	O00255-1.4	W203K	Pathogenic	1.0
MEN1	O00255-1.4	W203L	Pathogenic	1.0
MEN1	O00255-1.4	W203M	Pathogenic	1.0
MEN1	O00255-1.4	W203N	Pathogenic	1.0
MEN1	O00255-1.4	W203P	Pathogenic	1.0
MEN1	O00255-1.4	W203Q	Pathogenic	1.0
MEN1	O00255-1.4	W203R	Pathogenic	1.0
MEN1	O00255-1.4	W203S	Pathogenic	1.0
MEN1	O00255-1.4	W203T	Pathogenic	1.0
MEN1	O00255-1.4	W203V	Pathogenic	1.0
MEN1	O00255-1.4	W203Y	Pathogenic	1.0
MEN1	O00255-1.4	H204A	Pathogenic	0.999
MEN1	O00255-1.4	H204C	Pathogenic	0.999
MEN1	O00255-1.4	H204D	Pathogenic	0.999
MEN1	O00255-1.4	H204E	Pathogenic	0.993
MEN1	O00255-1.4	H204F	Pathogenic	0.999
MEN1	O00255-1.4	H204G	Pathogenic	1.0
MEN1	O00255-1.4	H204I	Pathogenic	0.998
MEN1	O00255-1.4	H204K	Pathogenic	0.998
MEN1	O00255-1.4	H204L	Pathogenic	0.998
MEN1	O00255-1.4	H204M	Pathogenic	0.996
MEN1	O00255-1.4	H204N	Pathogenic	0.997
MEN1	O00255-1.4	H204P	Pathogenic	0.998
MEN1	O00255-1.4	H204Q	Pathogenic	0.982
MEN1	O00255-1.4	H204R	Pathogenic	0.999
MEN1	O00255-1.4	H204S	Pathogenic	0.999
MEN1	O00255-1.4	H204T	Pathogenic	0.995
MEN1	O00255-1.4	H204V	Pathogenic	0.998
MEN1	O00255-1.4	H204W	Pathogenic	1.0
MEN1	O00255-1.4	H204Y	Pathogenic	0.998
MEN1	O00255-1.4	G205A	Pathogenic	0.925
MEN1	O00255-1.4	G205C	Pathogenic	0.995
MEN1	O00255-1.4	G205D	Pathogenic	0.994
MEN1	O00255-1.4	G205E	Pathogenic	0.998
MEN1	O00255-1.4	G205F	Pathogenic	1.0
MEN1	O00255-1.4	G205H	Pathogenic	0.998
MEN1	O00255-1.4	G205I	Pathogenic	1.0
MEN1	O00255-1.4	G205K	Pathogenic	1.0
MEN1	O00255-1.4	G205L	Pathogenic	1.0
MEN1	O00255-1.4	G205M	Pathogenic	1.0
MEN1	O00255-1.4	G205N	Pathogenic	0.994
MEN1	O00255-1.4	G205P	Pathogenic	0.993
MEN1	O00255-1.4	G205Q	Pathogenic	0.998
MEN1	O00255-1.4	G205R	Pathogenic	1.0
MEN1	O00255-1.4	G205S	Pathogenic	0.926
MEN1	O00255-1.4	G205T	Pathogenic	0.989
MEN1	O00255-1.4	G205V	Pathogenic	0.999
MEN1	O00255-1.4	G205W	Pathogenic	1.0
MEN1	O00255-1.4	G205Y	Pathogenic	1.0
MEN1	O00255-1.4	K206A	Pathogenic	1.0
MEN1	O00255-1.4	K206C	Pathogenic	1.0
MEN1	O00255-1.4	K206D	Pathogenic	0.995
MEN1	O00255-1.4	K206E	Pathogenic	0.983
MEN1	O00255-1.4	K206F	Pathogenic	0.998
MEN1	O00255-1.4	K206G	Pathogenic	1.0
MEN1	O00255-1.4	K206H	Pathogenic	0.991
MEN1	O00255-1.4	K206I	Pathogenic	0.999
MEN1	O00255-1.4	K206L	Pathogenic	0.999
MEN1	O00255-1.4	K206M	Pathogenic	0.998
MEN1	O00255-1.4	K206N	Pathogenic	0.994
MEN1	O00255-1.4	K206P	Pathogenic	1.0
MEN1	O00255-1.4	K206Q	Pathogenic	0.987
MEN1	O00255-1.4	K206R	Pathogenic	0.923
MEN1	O00255-1.4	K206S	Pathogenic	1.0
MEN1	O00255-1.4	K206T	Pathogenic	0.999
MEN1	O00255-1.4	K206V	Pathogenic	0.999
MEN1	O00255-1.4	K206W	Pathogenic	1.0
MEN1	O00255-1.4	K206Y	Pathogenic	0.995
MEN1	O00255-1.4	G207A	Pathogenic	0.927
MEN1	O00255-1.4	G207C	Pathogenic	0.995
MEN1	O00255-1.4	G207D	Pathogenic	0.994
MEN1	O00255-1.4	G207E	Pathogenic	0.998
MEN1	O00255-1.4	G207F	Pathogenic	1.0
MEN1	O00255-1.4	G207H	Pathogenic	0.998
MEN1	O00255-1.4	G207I	Pathogenic	1.0
MEN1	O00255-1.4	G207K	Pathogenic	1.0
MEN1	O00255-1.4	G207L	Pathogenic	1.0
MEN1	O00255-1.4	G207M	Pathogenic	1.0
MEN1	O00255-1.4	G207N	Pathogenic	0.994
MEN1	O00255-1.4	G207P	Pathogenic	0.994
MEN1	O00255-1.4	G207Q	Pathogenic	0.998
MEN1	O00255-1.4	G207R	Pathogenic	1.0
MEN1	O00255-1.4	G207S	Pathogenic	0.928
MEN1	O00255-1.4	G207T	Pathogenic	0.989
MEN1	O00255-1.4	G207V	Pathogenic	0.999
MEN1	O00255-1.4	G207W	Pathogenic	1.0
MEN1	O00255-1.4	G207Y	Pathogenic	1.0
MEN1	O00255-1.4	N208A	Pathogenic	0.992
MEN1	O00255-1.4	N208C	Pathogenic	0.99
MEN1	O00255-1.4	N208D	Pathogenic	0.844
MEN1	O00255-1.4	N208E	Pathogenic	0.894
MEN1	O00255-1.4	N208F	Pathogenic	1.0
MEN1	O00255-1.4	N208G	Pathogenic	0.997
MEN1	O00255-1.4	N208H	Pathogenic	0.98
MEN1	O00255-1.4	N208I	Pathogenic	0.999
MEN1	O00255-1.4	N208K	Pathogenic	0.99
MEN1	O00255-1.4	N208L	Pathogenic	0.999
MEN1	O00255-1.4	N208M	Pathogenic	0.998
MEN1	O00255-1.4	N208P	Pathogenic	0.978
MEN1	O00255-1.4	N208Q	Pathogenic	0.955
MEN1	O00255-1.4	N208R	Pathogenic	0.996
MEN1	O00255-1.4	N208S	Pathogenic	0.975
MEN1	O00255-1.4	N208T	Pathogenic	0.938
MEN1	O00255-1.4	N208V	Pathogenic	0.993
MEN1	O00255-1.4	N208W	Pathogenic	1.0
MEN1	O00255-1.4	N208Y	Pathogenic	0.999
MEN1	O00255-1.4	E209A	Pathogenic	0.995
MEN1	O00255-1.4	E209C	Pathogenic	0.994
MEN1	O00255-1.4	E209D	Pathogenic	0.876
MEN1	O00255-1.4	E209F	Pathogenic	0.999
MEN1	O00255-1.4	E209G	Pathogenic	0.998
MEN1	O00255-1.4	E209H	Pathogenic	0.92
MEN1	O00255-1.4	E209I	Pathogenic	0.997
MEN1	O00255-1.4	E209K	Pathogenic	0.951
MEN1	O00255-1.4	E209L	Pathogenic	0.996
MEN1	O00255-1.4	E209M	Pathogenic	0.992
MEN1	O00255-1.4	E209N	Pathogenic	0.824
MEN1	O00255-1.4	E209P	Pathogenic	0.985
MEN1	O00255-1.4	E209Q	Pathogenic	0.81
MEN1	O00255-1.4	E209R	Pathogenic	0.982
MEN1	O00255-1.4	E209S	Pathogenic	0.985
MEN1	O00255-1.4	E209T	Pathogenic	0.962
MEN1	O00255-1.4	E209V	Pathogenic	0.981
MEN1	O00255-1.4	E209W	Pathogenic	1.0
MEN1	O00255-1.4	E209Y	Pathogenic	0.996
MEN1	O00255-1.4	D210A	Pathogenic	0.994
MEN1	O00255-1.4	D210C	Pathogenic	0.992
MEN1	O00255-1.4	D210E	Pathogenic	0.947
MEN1	O00255-1.4	D210F	Pathogenic	1.0
MEN1	O00255-1.4	D210G	Pathogenic	0.997
MEN1	O00255-1.4	D210H	Pathogenic	0.993
MEN1	O00255-1.4	D210I	Pathogenic	1.0
MEN1	O00255-1.4	D210K	Pathogenic	0.994
MEN1	O00255-1.4	D210L	Pathogenic	1.0
MEN1	O00255-1.4	D210M	Pathogenic	0.999
MEN1	O00255-1.4	D210N	Pathogenic	0.885
MEN1	O00255-1.4	D210P	Pathogenic	0.982
MEN1	O00255-1.4	D210Q	Pathogenic	0.983
MEN1	O00255-1.4	D210R	Pathogenic	0.998
MEN1	O00255-1.4	D210S	Pathogenic	0.982
MEN1	O00255-1.4	D210T	Pathogenic	0.965
MEN1	O00255-1.4	D210V	Pathogenic	0.997
MEN1	O00255-1.4	D210W	Pathogenic	1.0
MEN1	O00255-1.4	D210Y	Pathogenic	1.0
MEN1	O00255-1.4	R211A	Pathogenic	0.998
MEN1	O00255-1.4	R211C	Pathogenic	0.998
MEN1	O00255-1.4	R211D	Pathogenic	0.939
MEN1	O00255-1.4	R211E	Pathogenic	0.815
MEN1	O00255-1.4	R211F	Pathogenic	0.975
MEN1	O00255-1.4	R211G	Pathogenic	0.999
MEN1	O00255-1.4	R211H	Pathogenic	0.887
MEN1	O00255-1.4	R211I	Pathogenic	0.989
MEN1	O00255-1.4	R211K	Neutral	0.24
MEN1	O00255-1.4	R211L	Pathogenic	0.986
MEN1	O00255-1.4	R211M	Pathogenic	0.969
MEN1	O00255-1.4	R211N	Pathogenic	0.925
MEN1	O00255-1.4	R211P	Pathogenic	0.995
MEN1	O00255-1.4	R211Q	Pathogenic	0.849
MEN1	O00255-1.4	R211S	Pathogenic	0.995
MEN1	O00255-1.4	R211T	Pathogenic	0.985
MEN1	O00255-1.4	R211V	Pathogenic	0.993
MEN1	O00255-1.4	R211W	Pathogenic	0.99
MEN1	O00255-1.4	R211Y	Pathogenic	0.859
MEN1	O00255-1.4	R212A	Pathogenic	1.0
MEN1	O00255-1.4	R212C	Pathogenic	1.0
MEN1	O00255-1.4	R212D	Pathogenic	0.997
MEN1	O00255-1.4	R212E	Pathogenic	0.99
MEN1	O00255-1.4	R212F	Pathogenic	0.999
MEN1	O00255-1.4	R212G	Pathogenic	1.0
MEN1	O00255-1.4	R212H	Pathogenic	0.994
MEN1	O00255-1.4	R212I	Pathogenic	0.999
MEN1	O00255-1.4	R212K	Pathogenic	0.872
MEN1	O00255-1.4	R212L	Pathogenic	0.999
MEN1	O00255-1.4	R212M	Pathogenic	0.999
MEN1	O00255-1.4	R212N	Pathogenic	0.996
MEN1	O00255-1.4	R212P	Pathogenic	1.0
MEN1	O00255-1.4	R212Q	Pathogenic	0.992
MEN1	O00255-1.4	R212S	Pathogenic	1.0
MEN1	O00255-1.4	R212T	Pathogenic	0.999
MEN1	O00255-1.4	R212V	Pathogenic	1.0
MEN1	O00255-1.4	R212W	Pathogenic	1.0
MEN1	O00255-1.4	R212Y	Pathogenic	0.992
MEN1	O00255-1.4	G213A	Pathogenic	0.932
MEN1	O00255-1.4	G213C	Pathogenic	0.995
MEN1	O00255-1.4	G213D	Pathogenic	0.995
MEN1	O00255-1.4	G213E	Pathogenic	0.998
MEN1	O00255-1.4	G213F	Pathogenic	1.0
MEN1	O00255-1.4	G213H	Pathogenic	0.998
MEN1	O00255-1.4	G213I	Pathogenic	1.0
MEN1	O00255-1.4	G213K	Pathogenic	1.0
MEN1	O00255-1.4	G213L	Pathogenic	1.0
MEN1	O00255-1.4	G213M	Pathogenic	1.0
MEN1	O00255-1.4	G213N	Pathogenic	0.995
MEN1	O00255-1.4	G213P	Pathogenic	0.994
MEN1	O00255-1.4	G213Q	Pathogenic	0.998
MEN1	O00255-1.4	G213R	Pathogenic	1.0
MEN1	O00255-1.4	G213S	Pathogenic	0.933
MEN1	O00255-1.4	G213T	Pathogenic	0.99
MEN1	O00255-1.4	G213V	Pathogenic	0.999
MEN1	O00255-1.4	G213W	Pathogenic	1.0
MEN1	O00255-1.4	G213Y	Pathogenic	1.0
MEN1	O00255-1.4	Q214A	Pathogenic	0.995
MEN1	O00255-1.4	Q214C	Pathogenic	0.994
MEN1	O00255-1.4	Q214D	Pathogenic	0.97
MEN1	O00255-1.4	Q214E	Pathogenic	0.858
MEN1	O00255-1.4	Q214F	Pathogenic	0.997
MEN1	O00255-1.4	Q214G	Pathogenic	0.998
MEN1	O00255-1.4	Q214H	Pathogenic	0.85
MEN1	O00255-1.4	Q214I	Pathogenic	0.994
MEN1	O00255-1.4	Q214K	Pathogenic	0.974
MEN1	O00255-1.4	Q214L	Pathogenic	0.992
MEN1	O00255-1.4	Q214M	Pathogenic	0.981
MEN1	O00255-1.4	Q214N	Pathogenic	0.944
MEN1	O00255-1.4	Q214P	Pathogenic	0.986
MEN1	O00255-1.4	Q214R	Pathogenic	0.99
MEN1	O00255-1.4	Q214S	Pathogenic	0.986
MEN1	O00255-1.4	Q214T	Pathogenic	0.963
MEN1	O00255-1.4	Q214V	Pathogenic	0.982
MEN1	O00255-1.4	Q214W	Pathogenic	1.0
MEN1	O00255-1.4	Q214Y	Pathogenic	0.992
MEN1	O00255-1.4	T215A	Neutral	0.272
MEN1	O00255-1.4	T215C	Neutral	0.223
MEN1	O00255-1.4	T215D	Neutral	0.243
MEN1	O00255-1.4	T215E	Neutral	0.425
MEN1	O00255-1.4	T215F	Pathogenic	0.939
MEN1	O00255-1.4	T215G	Pathogenic	0.709
MEN1	O00255-1.4	T215H	Neutral	0.306
MEN1	O00255-1.4	T215I	Pathogenic	0.867
MEN1	O00255-1.4	T215K	Pathogenic	0.901
MEN1	O00255-1.4	T215L	Pathogenic	0.847
MEN1	O00255-1.4	T215M	Pathogenic	0.721
MEN1	O00255-1.4	T215N	Neutral	0.199
MEN1	O00255-1.4	T215P	Neutral	0.122
MEN1	O00255-1.4	T215Q	Neutral	0.353
MEN1	O00255-1.4	T215R	Pathogenic	0.961
MEN1	O00255-1.4	T215S	Neutral	0.25
MEN1	O00255-1.4	T215V	Neutral	0.365
MEN1	O00255-1.4	T215W	Pathogenic	0.996
MEN1	O00255-1.4	T215Y	Pathogenic	0.863
MEN1	O00255-1.4	V216A	Pathogenic	0.957
MEN1	O00255-1.4	V216C	Pathogenic	0.657
MEN1	O00255-1.4	V216D	Pathogenic	0.962
MEN1	O00255-1.4	V216E	Pathogenic	0.902
MEN1	O00255-1.4	V216F	Pathogenic	0.883
MEN1	O00255-1.4	V216G	Pathogenic	0.995
MEN1	O00255-1.4	V216H	Pathogenic	0.846
MEN1	O00255-1.4	V216I	Pathogenic	0.727
MEN1	O00255-1.4	V216K	Pathogenic	0.991
MEN1	O00255-1.4	V216L	Pathogenic	0.718
MEN1	O00255-1.4	V216M	Pathogenic	0.543
MEN1	O00255-1.4	V216N	Pathogenic	0.93
MEN1	O00255-1.4	V216P	Pathogenic	0.698
MEN1	O00255-1.4	V216Q	Pathogenic	0.871
MEN1	O00255-1.4	V216R	Pathogenic	0.997
MEN1	O00255-1.4	V216S	Pathogenic	0.966
MEN1	O00255-1.4	V216T	Pathogenic	0.776
MEN1	O00255-1.4	V216W	Pathogenic	0.993
MEN1	O00255-1.4	V216Y	Pathogenic	0.876
MEN1	O00255-1.4	N217A	Neutral	0.198
MEN1	O00255-1.4	N217C	Neutral	0.159
MEN1	O00255-1.4	N217D	Neutral	0.01
MEN1	O00255-1.4	N217E	Neutral	0.016
MEN1	O00255-1.4	N217F	Pathogenic	0.859
MEN1	O00255-1.4	N217G	Neutral	0.355
MEN1	O00255-1.4	N217H	Neutral	0.084
MEN1	O00255-1.4	N217I	Pathogenic	0.734
MEN1	O00255-1.4	N217K	Neutral	0.166
MEN1	O00255-1.4	N217L	Pathogenic	0.7
MEN1	O00255-1.4	N217M	Pathogenic	0.506
MEN1	O00255-1.4	N217P	Neutral	0.079
MEN1	O00255-1.4	N217Q	Neutral	0.039
MEN1	O00255-1.4	N217R	Neutral	0.349
MEN1	O00255-1.4	N217S	Neutral	0.07
MEN1	O00255-1.4	N217T	Neutral	0.028
MEN1	O00255-1.4	N217V	Neutral	0.205
MEN1	O00255-1.4	N217W	Pathogenic	0.991
MEN1	O00255-1.4	N217Y	Pathogenic	0.702
MEN1	O00255-1.4	A218C	Neutral	0.034
MEN1	O00255-1.4	A218D	Neutral	0.099
MEN1	O00255-1.4	A218E	Neutral	0.242
MEN1	O00255-1.4	A218F	Pathogenic	0.849
MEN1	O00255-1.4	A218G	Neutral	0.019
MEN1	O00255-1.4	A218H	Neutral	0.16
MEN1	O00255-1.4	A218I	Pathogenic	0.705
MEN1	O00255-1.4	A218K	Pathogenic	0.798
MEN1	O00255-1.4	A218L	Pathogenic	0.669
MEN1	O00255-1.4	A218M	Neutral	0.486
MEN1	O00255-1.4	A218N	Neutral	0.108
MEN1	O00255-1.4	A218P	Neutral	0.031
MEN1	O00255-1.4	A218Q	Neutral	0.191
MEN1	O00255-1.4	A218R	Pathogenic	0.914
MEN1	O00255-1.4	A218S	Neutral	0.007
MEN1	O00255-1.4	A218T	Neutral	0.021
MEN1	O00255-1.4	A218V	Neutral	0.174
MEN1	O00255-1.4	A218W	Pathogenic	0.99
MEN1	O00255-1.4	A218Y	Pathogenic	0.697
MEN1	O00255-1.4	G219A	Pathogenic	0.98
MEN1	O00255-1.4	G219C	Pathogenic	0.999
MEN1	O00255-1.4	G219D	Pathogenic	0.998
MEN1	O00255-1.4	G219E	Pathogenic	1.0
MEN1	O00255-1.4	G219F	Pathogenic	1.0
MEN1	O00255-1.4	G219H	Pathogenic	0.999
MEN1	O00255-1.4	G219I	Pathogenic	1.0
MEN1	O00255-1.4	G219K	Pathogenic	1.0
MEN1	O00255-1.4	G219L	Pathogenic	1.0
MEN1	O00255-1.4	G219M	Pathogenic	1.0
MEN1	O00255-1.4	G219N	Pathogenic	0.999
MEN1	O00255-1.4	G219P	Pathogenic	0.998
MEN1	O00255-1.4	G219Q	Pathogenic	0.999
MEN1	O00255-1.4	G219R	Pathogenic	1.0
MEN1	O00255-1.4	G219S	Pathogenic	0.98
MEN1	O00255-1.4	G219T	Pathogenic	0.997
MEN1	O00255-1.4	G219V	Pathogenic	1.0
MEN1	O00255-1.4	G219W	Pathogenic	1.0
MEN1	O00255-1.4	G219Y	Pathogenic	1.0
MEN1	O00255-1.4	V220A	Pathogenic	0.971
MEN1	O00255-1.4	V220C	Pathogenic	0.743
MEN1	O00255-1.4	V220D	Pathogenic	0.975
MEN1	O00255-1.4	V220E	Pathogenic	0.933
MEN1	O00255-1.4	V220F	Pathogenic	0.919
MEN1	O00255-1.4	V220G	Pathogenic	0.996
MEN1	O00255-1.4	V220H	Pathogenic	0.892
MEN1	O00255-1.4	V220I	Pathogenic	0.801
MEN1	O00255-1.4	V220K	Pathogenic	0.994
MEN1	O00255-1.4	V220L	Pathogenic	0.794
MEN1	O00255-1.4	V220M	Pathogenic	0.642
MEN1	O00255-1.4	V220N	Pathogenic	0.953
MEN1	O00255-1.4	V220P	Pathogenic	0.778
MEN1	O00255-1.4	V220Q	Pathogenic	0.911
MEN1	O00255-1.4	V220R	Pathogenic	0.998
MEN1	O00255-1.4	V220S	Pathogenic	0.977
MEN1	O00255-1.4	V220T	Pathogenic	0.84
MEN1	O00255-1.4	V220W	Pathogenic	0.995
MEN1	O00255-1.4	V220Y	Pathogenic	0.914
MEN1	O00255-1.4	A221C	Neutral	0.136
MEN1	O00255-1.4	A221D	Neutral	0.331
MEN1	O00255-1.4	A221E	Pathogenic	0.591
MEN1	O00255-1.4	A221F	Pathogenic	0.962
MEN1	O00255-1.4	A221G	Neutral	0.08
MEN1	O00255-1.4	A221H	Neutral	0.463
MEN1	O00255-1.4	A221I	Pathogenic	0.915
MEN1	O00255-1.4	A221K	Pathogenic	0.947
MEN1	O00255-1.4	A221L	Pathogenic	0.901
MEN1	O00255-1.4	A221M	Pathogenic	0.81
MEN1	O00255-1.4	A221N	Neutral	0.354
MEN1	O00255-1.4	A221P	Neutral	0.128
MEN1	O00255-1.4	A221Q	Pathogenic	0.516
MEN1	O00255-1.4	A221R	Pathogenic	0.98
MEN1	O00255-1.4	A221S	Neutral	0.032
MEN1	O00255-1.4	A221T	Neutral	0.088
MEN1	O00255-1.4	A221V	Neutral	0.487
MEN1	O00255-1.4	A221W	Pathogenic	0.998
MEN1	O00255-1.4	A221Y	Pathogenic	0.912
MEN1	O00255-1.4	E222A	Pathogenic	0.946
MEN1	O00255-1.4	E222C	Pathogenic	0.938
MEN1	O00255-1.4	E222D	Neutral	0.393
MEN1	O00255-1.4	E222F	Pathogenic	0.985
MEN1	O00255-1.4	E222G	Pathogenic	0.979
MEN1	O00255-1.4	E222H	Pathogenic	0.512
MEN1	O00255-1.4	E222I	Pathogenic	0.967
MEN1	O00255-1.4	E222K	Pathogenic	0.641
MEN1	O00255-1.4	E222L	Pathogenic	0.962
MEN1	O00255-1.4	E222M	Pathogenic	0.917
MEN1	O00255-1.4	E222N	Neutral	0.301
MEN1	O00255-1.4	E222P	Pathogenic	0.859
MEN1	O00255-1.4	E222Q	Neutral	0.28
MEN1	O00255-1.4	E222R	Pathogenic	0.837
MEN1	O00255-1.4	E222S	Pathogenic	0.857
MEN1	O00255-1.4	E222T	Pathogenic	0.697
MEN1	O00255-1.4	E222V	Pathogenic	0.826
MEN1	O00255-1.4	E222W	Pathogenic	0.999
MEN1	O00255-1.4	E222Y	Pathogenic	0.962
MEN1	O00255-1.4	R223A	Pathogenic	1.0
MEN1	O00255-1.4	R223C	Pathogenic	0.999
MEN1	O00255-1.4	R223D	Pathogenic	0.985
MEN1	O00255-1.4	R223E	Pathogenic	0.951
MEN1	O00255-1.4	R223F	Pathogenic	0.994
MEN1	O00255-1.4	R223G	Pathogenic	1.0
MEN1	O00255-1.4	R223H	Pathogenic	0.972
MEN1	O00255-1.4	R223I	Pathogenic	0.997
MEN1	O00255-1.4	R223K	Pathogenic	0.58
MEN1	O00255-1.4	R223L	Pathogenic	0.997
MEN1	O00255-1.4	R223M	Pathogenic	0.993
MEN1	O00255-1.4	R223N	Pathogenic	0.982
MEN1	O00255-1.4	R223P	Pathogenic	0.999
MEN1	O00255-1.4	R223Q	Pathogenic	0.961
MEN1	O00255-1.4	R223S	Pathogenic	0.999
MEN1	O00255-1.4	R223T	Pathogenic	0.997
MEN1	O00255-1.4	R223V	Pathogenic	0.998
MEN1	O00255-1.4	R223W	Pathogenic	0.998
MEN1	O00255-1.4	R223Y	Pathogenic	0.964
MEN1	O00255-1.4	S224A	Pathogenic	0.957
MEN1	O00255-1.4	S224C	Pathogenic	0.992
MEN1	O00255-1.4	S224D	Pathogenic	0.991
MEN1	O00255-1.4	S224E	Pathogenic	0.997
MEN1	O00255-1.4	S224F	Pathogenic	1.0
MEN1	O00255-1.4	S224G	Pathogenic	0.983
MEN1	O00255-1.4	S224H	Pathogenic	0.997
MEN1	O00255-1.4	S224I	Pathogenic	1.0
MEN1	O00255-1.4	S224K	Pathogenic	1.0
MEN1	O00255-1.4	S224L	Pathogenic	1.0
MEN1	O00255-1.4	S224M	Pathogenic	1.0
MEN1	O00255-1.4	S224N	Pathogenic	0.991
MEN1	O00255-1.4	S224P	Pathogenic	0.991
MEN1	O00255-1.4	S224Q	Pathogenic	0.996
MEN1	O00255-1.4	S224R	Pathogenic	1.0
MEN1	O00255-1.4	S224T	Pathogenic	0.983
MEN1	O00255-1.4	S224V	Pathogenic	0.999
MEN1	O00255-1.4	S224W	Pathogenic	1.0
MEN1	O00255-1.4	S224Y	Pathogenic	1.0
MEN1	O00255-1.4	W225A	Pathogenic	1.0
MEN1	O00255-1.4	W225C	Pathogenic	1.0
MEN1	O00255-1.4	W225D	Pathogenic	1.0
MEN1	O00255-1.4	W225E	Pathogenic	1.0
MEN1	O00255-1.4	W225F	Pathogenic	1.0
MEN1	O00255-1.4	W225G	Pathogenic	1.0
MEN1	O00255-1.4	W225H	Pathogenic	1.0
MEN1	O00255-1.4	W225I	Pathogenic	1.0
MEN1	O00255-1.4	W225K	Pathogenic	1.0
MEN1	O00255-1.4	W225L	Pathogenic	1.0
MEN1	O00255-1.4	W225M	Pathogenic	1.0
MEN1	O00255-1.4	W225N	Pathogenic	1.0
MEN1	O00255-1.4	W225P	Pathogenic	1.0
MEN1	O00255-1.4	W225Q	Pathogenic	1.0
MEN1	O00255-1.4	W225R	Pathogenic	1.0
MEN1	O00255-1.4	W225S	Pathogenic	1.0
MEN1	O00255-1.4	W225T	Pathogenic	1.0
MEN1	O00255-1.4	W225V	Pathogenic	1.0
MEN1	O00255-1.4	W225Y	Pathogenic	1.0
MEN1	O00255-1.4	L226A	Pathogenic	1.0
MEN1	O00255-1.4	L226C	Pathogenic	0.998
MEN1	O00255-1.4	L226D	Pathogenic	1.0
MEN1	O00255-1.4	L226E	Pathogenic	0.999
MEN1	O00255-1.4	L226F	Pathogenic	0.958
MEN1	O00255-1.4	L226G	Pathogenic	1.0
MEN1	O00255-1.4	L226H	Pathogenic	0.995
MEN1	O00255-1.4	L226I	Pathogenic	0.901
MEN1	O00255-1.4	L226K	Pathogenic	0.999
MEN1	O00255-1.4	L226M	Pathogenic	0.943
MEN1	O00255-1.4	L226N	Pathogenic	1.0
MEN1	O00255-1.4	L226P	Pathogenic	0.998
MEN1	O00255-1.4	L226Q	Pathogenic	0.998
MEN1	O00255-1.4	L226R	Pathogenic	1.0
MEN1	O00255-1.4	L226S	Pathogenic	1.0
MEN1	O00255-1.4	L226T	Pathogenic	0.999
MEN1	O00255-1.4	L226V	Pathogenic	0.987
MEN1	O00255-1.4	L226W	Pathogenic	0.998
MEN1	O00255-1.4	L226Y	Pathogenic	0.991
MEN1	O00255-1.4	Y227A	Pathogenic	1.0
MEN1	O00255-1.4	Y227C	Pathogenic	1.0
MEN1	O00255-1.4	Y227D	Pathogenic	1.0
MEN1	O00255-1.4	Y227E	Pathogenic	1.0
MEN1	O00255-1.4	Y227F	Pathogenic	0.998
MEN1	O00255-1.4	Y227G	Pathogenic	1.0
MEN1	O00255-1.4	Y227H	Pathogenic	0.999
MEN1	O00255-1.4	Y227I	Pathogenic	0.999
MEN1	O00255-1.4	Y227K	Pathogenic	1.0
MEN1	O00255-1.4	Y227L	Pathogenic	0.999
MEN1	O00255-1.4	Y227M	Pathogenic	0.998
MEN1	O00255-1.4	Y227N	Pathogenic	1.0
MEN1	O00255-1.4	Y227P	Pathogenic	1.0
MEN1	O00255-1.4	Y227Q	Pathogenic	1.0
MEN1	O00255-1.4	Y227R	Pathogenic	1.0
MEN1	O00255-1.4	Y227S	Pathogenic	1.0
MEN1	O00255-1.4	Y227T	Pathogenic	1.0
MEN1	O00255-1.4	Y227V	Pathogenic	1.0
MEN1	O00255-1.4	Y227W	Pathogenic	1.0
MEN1	O00255-1.4	L228A	Pathogenic	0.999
MEN1	O00255-1.4	L228C	Pathogenic	0.985
MEN1	O00255-1.4	L228D	Pathogenic	0.999
MEN1	O00255-1.4	L228E	Pathogenic	0.995
MEN1	O00255-1.4	L228F	Pathogenic	0.752
MEN1	O00255-1.4	L228G	Pathogenic	1.0
MEN1	O00255-1.4	L228H	Pathogenic	0.965
MEN1	O00255-1.4	L228I	Pathogenic	0.547
MEN1	O00255-1.4	L228K	Pathogenic	0.996
MEN1	O00255-1.4	L228M	Pathogenic	0.687
MEN1	O00255-1.4	L228N	Pathogenic	0.998
MEN1	O00255-1.4	L228P	Pathogenic	0.989
MEN1	O00255-1.4	L228Q	Pathogenic	0.984
MEN1	O00255-1.4	L228R	Pathogenic	0.998
MEN1	O00255-1.4	L228S	Pathogenic	0.999
MEN1	O00255-1.4	L228T	Pathogenic	0.992
MEN1	O00255-1.4	L228V	Pathogenic	0.908
MEN1	O00255-1.4	L228W	Pathogenic	0.983
MEN1	O00255-1.4	L228Y	Pathogenic	0.936
MEN1	O00255-1.4	K229A	Pathogenic	0.999
MEN1	O00255-1.4	K229C	Pathogenic	0.999
MEN1	O00255-1.4	K229D	Pathogenic	0.96
MEN1	O00255-1.4	K229E	Pathogenic	0.874
MEN1	O00255-1.4	K229F	Pathogenic	0.985
MEN1	O00255-1.4	K229G	Pathogenic	1.0
MEN1	O00255-1.4	K229H	Pathogenic	0.933
MEN1	O00255-1.4	K229I	Pathogenic	0.993
MEN1	O00255-1.4	K229L	Pathogenic	0.992
MEN1	O00255-1.4	K229M	Pathogenic	0.981
MEN1	O00255-1.4	K229N	Pathogenic	0.954
MEN1	O00255-1.4	K229P	Pathogenic	0.997
MEN1	O00255-1.4	K229Q	Pathogenic	0.904
MEN1	O00255-1.4	K229R	Pathogenic	0.588
MEN1	O00255-1.4	K229S	Pathogenic	0.997
MEN1	O00255-1.4	K229T	Pathogenic	0.991
MEN1	O00255-1.4	K229V	Pathogenic	0.996
MEN1	O00255-1.4	K229W	Pathogenic	0.999
MEN1	O00255-1.4	K229Y	Pathogenic	0.961
MEN1	O00255-1.4	G230A	Pathogenic	0.992
MEN1	O00255-1.4	G230C	Pathogenic	0.999
MEN1	O00255-1.4	G230D	Pathogenic	0.999
MEN1	O00255-1.4	G230E	Pathogenic	1.0
MEN1	O00255-1.4	G230F	Pathogenic	1.0
MEN1	O00255-1.4	G230H	Pathogenic	1.0
MEN1	O00255-1.4	G230I	Pathogenic	1.0
MEN1	O00255-1.4	G230K	Pathogenic	1.0
MEN1	O00255-1.4	G230L	Pathogenic	1.0
MEN1	O00255-1.4	G230M	Pathogenic	1.0
MEN1	O00255-1.4	G230N	Pathogenic	0.999
MEN1	O00255-1.4	G230P	Pathogenic	0.999
MEN1	O00255-1.4	G230Q	Pathogenic	1.0
MEN1	O00255-1.4	G230R	Pathogenic	1.0
MEN1	O00255-1.4	G230S	Pathogenic	0.992
MEN1	O00255-1.4	G230T	Pathogenic	0.999
MEN1	O00255-1.4	G230V	Pathogenic	1.0
MEN1	O00255-1.4	G230W	Pathogenic	1.0
MEN1	O00255-1.4	G230Y	Pathogenic	1.0
MEN1	O00255-1.4	S231A	Neutral	0.089
MEN1	O00255-1.4	S231C	Neutral	0.358
MEN1	O00255-1.4	S231D	Neutral	0.325
MEN1	O00255-1.4	S231E	Pathogenic	0.598
MEN1	O00255-1.4	S231F	Pathogenic	0.988
MEN1	O00255-1.4	S231G	Neutral	0.207
MEN1	O00255-1.4	S231H	Pathogenic	0.605
MEN1	O00255-1.4	S231I	Pathogenic	0.975
MEN1	O00255-1.4	S231K	Pathogenic	0.948
MEN1	O00255-1.4	S231L	Pathogenic	0.97
MEN1	O00255-1.4	S231M	Pathogenic	0.935
MEN1	O00255-1.4	S231N	Neutral	0.333
MEN1	O00255-1.4	S231P	Neutral	0.329
MEN1	O00255-1.4	S231Q	Pathogenic	0.523
MEN1	O00255-1.4	S231R	Pathogenic	0.981
MEN1	O00255-1.4	S231T	Neutral	0.205
MEN1	O00255-1.4	S231V	Pathogenic	0.782
MEN1	O00255-1.4	S231W	Pathogenic	0.999
MEN1	O00255-1.4	S231Y	Pathogenic	0.972
MEN1	O00255-1.4	Y232A	Pathogenic	0.999
MEN1	O00255-1.4	Y232C	Pathogenic	0.993
MEN1	O00255-1.4	Y232D	Pathogenic	0.999
MEN1	O00255-1.4	Y232E	Pathogenic	0.997
MEN1	O00255-1.4	Y232F	Pathogenic	0.904
MEN1	O00255-1.4	Y232G	Pathogenic	1.0
MEN1	O00255-1.4	Y232H	Pathogenic	0.973
MEN1	O00255-1.4	Y232I	Pathogenic	0.965
MEN1	O00255-1.4	Y232K	Pathogenic	0.987
MEN1	O00255-1.4	Y232L	Pathogenic	0.959
MEN1	O00255-1.4	Y232M	Pathogenic	0.917
MEN1	O00255-1.4	Y232N	Pathogenic	0.999
MEN1	O00255-1.4	Y232P	Pathogenic	0.993
MEN1	O00255-1.4	Y232Q	Pathogenic	0.99
MEN1	O00255-1.4	Y232R	Pathogenic	0.989
MEN1	O00255-1.4	Y232S	Pathogenic	0.999
MEN1	O00255-1.4	Y232T	Pathogenic	0.996
MEN1	O00255-1.4	Y232V	Pathogenic	0.978
MEN1	O00255-1.4	Y232W	Pathogenic	0.986
MEN1	O00255-1.4	M233A	Pathogenic	0.999
MEN1	O00255-1.4	M233C	Pathogenic	0.989
MEN1	O00255-1.4	M233D	Pathogenic	0.999
MEN1	O00255-1.4	M233E	Pathogenic	0.996
MEN1	O00255-1.4	M233F	Pathogenic	0.951
MEN1	O00255-1.4	M233G	Pathogenic	1.0
MEN1	O00255-1.4	M233H	Pathogenic	0.973
MEN1	O00255-1.4	M233I	Pathogenic	0.891
MEN1	O00255-1.4	M233K	Pathogenic	0.997
MEN1	O00255-1.4	M233L	Pathogenic	0.867
MEN1	O00255-1.4	M233N	Pathogenic	0.998
MEN1	O00255-1.4	M233P	Pathogenic	0.991
MEN1	O00255-1.4	M233Q	Pathogenic	0.987
MEN1	O00255-1.4	M233R	Pathogenic	0.999
MEN1	O00255-1.4	M233S	Pathogenic	0.999
MEN1	O00255-1.4	M233T	Pathogenic	0.994
MEN1	O00255-1.4	M233V	Pathogenic	0.932
MEN1	O00255-1.4	M233W	Pathogenic	0.997
MEN1	O00255-1.4	M233Y	Pathogenic	0.953
MEN1	O00255-1.4	R234A	Pathogenic	0.993
MEN1	O00255-1.4	R234C	Pathogenic	0.991
MEN1	O00255-1.4	R234D	Pathogenic	0.806
MEN1	O00255-1.4	R234E	Pathogenic	0.544
MEN1	O00255-1.4	R234F	Pathogenic	0.913
MEN1	O00255-1.4	R234G	Pathogenic	0.997
MEN1	O00255-1.4	R234H	Pathogenic	0.68
MEN1	O00255-1.4	R234I	Pathogenic	0.961
MEN1	O00255-1.4	R234K	Neutral	0.079
MEN1	O00255-1.4	R234L	Pathogenic	0.951
MEN1	O00255-1.4	R234M	Pathogenic	0.895
MEN1	O00255-1.4	R234N	Pathogenic	0.77
MEN1	O00255-1.4	R234P	Pathogenic	0.98
MEN1	O00255-1.4	R234Q	Pathogenic	0.603
MEN1	O00255-1.4	R234S	Pathogenic	0.98
MEN1	O00255-1.4	R234T	Pathogenic	0.947
MEN1	O00255-1.4	R234V	Pathogenic	0.975
MEN1	O00255-1.4	R234W	Pathogenic	0.963
MEN1	O00255-1.4	R234Y	Pathogenic	0.622
MEN1	O00255-1.4	C235A	Pathogenic	1.0
MEN1	O00255-1.4	C235D	Pathogenic	1.0
MEN1	O00255-1.4	C235E	Pathogenic	1.0
MEN1	O00255-1.4	C235F	Pathogenic	1.0
MEN1	O00255-1.4	C235G	Pathogenic	1.0
MEN1	O00255-1.4	C235H	Pathogenic	1.0
MEN1	O00255-1.4	C235I	Pathogenic	1.0
MEN1	O00255-1.4	C235K	Pathogenic	1.0
MEN1	O00255-1.4	C235L	Pathogenic	1.0
MEN1	O00255-1.4	C235M	Pathogenic	1.0
MEN1	O00255-1.4	C235N	Pathogenic	1.0
MEN1	O00255-1.4	C235P	Pathogenic	0.999
MEN1	O00255-1.4	C235Q	Pathogenic	1.0
MEN1	O00255-1.4	C235R	Pathogenic	1.0
MEN1	O00255-1.4	C235S	Pathogenic	1.0
MEN1	O00255-1.4	C235T	Pathogenic	1.0
MEN1	O00255-1.4	C235V	Pathogenic	1.0
MEN1	O00255-1.4	C235W	Pathogenic	1.0
MEN1	O00255-1.4	C235Y	Pathogenic	1.0
MEN1	O00255-1.4	D236A	Pathogenic	0.925
MEN1	O00255-1.4	D236C	Pathogenic	0.904
MEN1	O00255-1.4	D236E	Pathogenic	0.571
MEN1	O00255-1.4	D236F	Pathogenic	0.998
MEN1	O00255-1.4	D236G	Pathogenic	0.967
MEN1	O00255-1.4	D236H	Pathogenic	0.916
MEN1	O00255-1.4	D236I	Pathogenic	0.997
MEN1	O00255-1.4	D236K	Pathogenic	0.928
MEN1	O00255-1.4	D236L	Pathogenic	0.996
MEN1	O00255-1.4	D236M	Pathogenic	0.991
MEN1	O00255-1.4	D236N	Neutral	0.363
MEN1	O00255-1.4	D236P	Pathogenic	0.802
MEN1	O00255-1.4	D236Q	Pathogenic	0.811
MEN1	O00255-1.4	D236R	Pathogenic	0.974
MEN1	O00255-1.4	D236S	Pathogenic	0.799
MEN1	O00255-1.4	D236T	Pathogenic	0.673
MEN1	O00255-1.4	D236V	Pathogenic	0.964
MEN1	O00255-1.4	D236W	Pathogenic	1.0
MEN1	O00255-1.4	D236Y	Pathogenic	0.996
MEN1	O00255-1.4	R237A	Pathogenic	1.0
MEN1	O00255-1.4	R237C	Pathogenic	1.0
MEN1	O00255-1.4	R237D	Pathogenic	1.0
MEN1	O00255-1.4	R237E	Pathogenic	0.999
MEN1	O00255-1.4	R237F	Pathogenic	1.0
MEN1	O00255-1.4	R237G	Pathogenic	1.0
MEN1	O00255-1.4	R237H	Pathogenic	0.999
MEN1	O00255-1.4	R237I	Pathogenic	1.0
MEN1	O00255-1.4	R237K	Pathogenic	0.987
MEN1	O00255-1.4	R237L	Pathogenic	1.0
MEN1	O00255-1.4	R237M	Pathogenic	1.0
MEN1	O00255-1.4	R237N	Pathogenic	1.0
MEN1	O00255-1.4	R237P	Pathogenic	1.0
MEN1	O00255-1.4	R237Q	Pathogenic	0.999
MEN1	O00255-1.4	R237S	Pathogenic	1.0
MEN1	O00255-1.4	R237T	Pathogenic	1.0
MEN1	O00255-1.4	R237V	Pathogenic	1.0
MEN1	O00255-1.4	R237W	Pathogenic	1.0
MEN1	O00255-1.4	R237Y	Pathogenic	0.999
MEN1	O00255-1.4	K238A	Pathogenic	0.964
MEN1	O00255-1.4	K238C	Pathogenic	0.956
MEN1	O00255-1.4	K238D	Neutral	0.436
MEN1	O00255-1.4	K238E	Neutral	0.181
MEN1	O00255-1.4	K238F	Pathogenic	0.674
MEN1	O00255-1.4	K238G	Pathogenic	0.986
MEN1	O00255-1.4	K238H	Neutral	0.308
MEN1	O00255-1.4	K238I	Pathogenic	0.828
MEN1	O00255-1.4	K238L	Pathogenic	0.793
MEN1	O00255-1.4	K238M	Pathogenic	0.628
MEN1	O00255-1.4	K238N	Neutral	0.397
MEN1	O00255-1.4	K238P	Pathogenic	0.903
MEN1	O00255-1.4	K238Q	Neutral	0.231
MEN1	O00255-1.4	K238R	Neutral	0.044
MEN1	O00255-1.4	K238S	Pathogenic	0.902
MEN1	O00255-1.4	K238T	Pathogenic	0.779
MEN1	O00255-1.4	K238V	Pathogenic	0.879
MEN1	O00255-1.4	K238W	Pathogenic	0.973
MEN1	O00255-1.4	K238Y	Neutral	0.443
MEN1	O00255-1.4	M239A	Pathogenic	1.0
MEN1	O00255-1.4	M239C	Pathogenic	1.0
MEN1	O00255-1.4	M239D	Pathogenic	1.0
MEN1	O00255-1.4	M239E	Pathogenic	1.0
MEN1	O00255-1.4	M239F	Pathogenic	0.998
MEN1	O00255-1.4	M239G	Pathogenic	1.0
MEN1	O00255-1.4	M239H	Pathogenic	0.999
MEN1	O00255-1.4	M239I	Pathogenic	0.996
MEN1	O00255-1.4	M239K	Pathogenic	1.0
MEN1	O00255-1.4	M239L	Pathogenic	0.995
MEN1	O00255-1.4	M239N	Pathogenic	1.0
MEN1	O00255-1.4	M239P	Pathogenic	1.0
MEN1	O00255-1.4	M239Q	Pathogenic	1.0
MEN1	O00255-1.4	M239R	Pathogenic	1.0
MEN1	O00255-1.4	M239S	Pathogenic	1.0
MEN1	O00255-1.4	M239T	Pathogenic	1.0
MEN1	O00255-1.4	M239V	Pathogenic	0.998
MEN1	O00255-1.4	M239W	Pathogenic	1.0
MEN1	O00255-1.4	M239Y	Pathogenic	0.998
MEN1	O00255-1.4	E240A	Pathogenic	1.0
MEN1	O00255-1.4	E240C	Pathogenic	1.0
MEN1	O00255-1.4	E240D	Pathogenic	0.99
MEN1	O00255-1.4	E240F	Pathogenic	1.0
MEN1	O00255-1.4	E240G	Pathogenic	1.0
MEN1	O00255-1.4	E240H	Pathogenic	0.994
MEN1	O00255-1.4	E240I	Pathogenic	1.0
MEN1	O00255-1.4	E240K	Pathogenic	0.997
MEN1	O00255-1.4	E240L	Pathogenic	1.0
MEN1	O00255-1.4	E240M	Pathogenic	0.999
MEN1	O00255-1.4	E240N	Pathogenic	0.986
MEN1	O00255-1.4	E240P	Pathogenic	0.999
MEN1	O00255-1.4	E240Q	Pathogenic	0.984
MEN1	O00255-1.4	E240R	Pathogenic	0.999
MEN1	O00255-1.4	E240S	Pathogenic	0.999
MEN1	O00255-1.4	E240T	Pathogenic	0.997
MEN1	O00255-1.4	E240V	Pathogenic	0.999
MEN1	O00255-1.4	E240W	Pathogenic	1.0
MEN1	O00255-1.4	E240Y	Pathogenic	1.0
MEN1	O00255-1.4	V241A	Pathogenic	0.997
MEN1	O00255-1.4	V241C	Pathogenic	0.969
MEN1	O00255-1.4	V241D	Pathogenic	0.998
MEN1	O00255-1.4	V241E	Pathogenic	0.993
MEN1	O00255-1.4	V241F	Pathogenic	0.992
MEN1	O00255-1.4	V241G	Pathogenic	1.0
MEN1	O00255-1.4	V241H	Pathogenic	0.989
MEN1	O00255-1.4	V241I	Pathogenic	0.977
MEN1	O00255-1.4	V241K	Pathogenic	0.999
MEN1	O00255-1.4	V241L	Pathogenic	0.976
MEN1	O00255-1.4	V241M	Pathogenic	0.951
MEN1	O00255-1.4	V241N	Pathogenic	0.995
MEN1	O00255-1.4	V241P	Pathogenic	0.974
MEN1	O00255-1.4	V241Q	Pathogenic	0.991
MEN1	O00255-1.4	V241R	Pathogenic	1.0
MEN1	O00255-1.4	V241S	Pathogenic	0.998
MEN1	O00255-1.4	V241T	Pathogenic	0.983
MEN1	O00255-1.4	V241W	Pathogenic	1.0
MEN1	O00255-1.4	V241Y	Pathogenic	0.991
MEN1	O00255-1.4	A242C	Pathogenic	0.995
MEN1	O00255-1.4	A242D	Pathogenic	0.998
MEN1	O00255-1.4	A242E	Pathogenic	0.999
MEN1	O00255-1.4	A242F	Pathogenic	1.0
MEN1	O00255-1.4	A242G	Pathogenic	0.99
MEN1	O00255-1.4	A242H	Pathogenic	0.999
MEN1	O00255-1.4	A242I	Pathogenic	1.0
MEN1	O00255-1.4	A242K	Pathogenic	1.0
MEN1	O00255-1.4	A242L	Pathogenic	1.0
MEN1	O00255-1.4	A242M	Pathogenic	1.0
MEN1	O00255-1.4	A242N	Pathogenic	0.998
MEN1	O00255-1.4	A242P	Pathogenic	0.994
MEN1	O00255-1.4	A242Q	Pathogenic	0.999
MEN1	O00255-1.4	A242R	Pathogenic	1.0
MEN1	O00255-1.4	A242S	Pathogenic	0.975
MEN1	O00255-1.4	A242T	Pathogenic	0.991
MEN1	O00255-1.4	A242V	Pathogenic	0.999
MEN1	O00255-1.4	A242W	Pathogenic	1.0
MEN1	O00255-1.4	A242Y	Pathogenic	1.0
MEN1	O00255-1.4	F243A	Pathogenic	1.0
MEN1	O00255-1.4	F243C	Pathogenic	0.996
MEN1	O00255-1.4	F243D	Pathogenic	1.0
MEN1	O00255-1.4	F243E	Pathogenic	0.999
MEN1	O00255-1.4	F243G	Pathogenic	1.0
MEN1	O00255-1.4	F243H	Pathogenic	0.989
MEN1	O00255-1.4	F243I	Pathogenic	0.797
MEN1	O00255-1.4	F243K	Pathogenic	0.995
MEN1	O00255-1.4	F243L	Pathogenic	0.815
MEN1	O00255-1.4	F243M	Pathogenic	0.904
MEN1	O00255-1.4	F243N	Pathogenic	0.999
MEN1	O00255-1.4	F243P	Pathogenic	0.997
MEN1	O00255-1.4	F243Q	Pathogenic	0.996
MEN1	O00255-1.4	F243R	Pathogenic	0.998
MEN1	O00255-1.4	F243S	Pathogenic	1.0
MEN1	O00255-1.4	F243T	Pathogenic	0.998
MEN1	O00255-1.4	F243V	Pathogenic	0.977
MEN1	O00255-1.4	F243W	Pathogenic	0.964
MEN1	O00255-1.4	F243Y	Pathogenic	0.894
MEN1	O00255-1.4	M244A	Pathogenic	1.0
MEN1	O00255-1.4	M244C	Pathogenic	0.996
MEN1	O00255-1.4	M244D	Pathogenic	1.0
MEN1	O00255-1.4	M244E	Pathogenic	0.998
MEN1	O00255-1.4	M244F	Pathogenic	0.979
MEN1	O00255-1.4	M244G	Pathogenic	1.0
MEN1	O00255-1.4	M244H	Pathogenic	0.989
MEN1	O00255-1.4	M244I	Pathogenic	0.952
MEN1	O00255-1.4	M244K	Pathogenic	0.999
MEN1	O00255-1.4	M244L	Pathogenic	0.94
MEN1	O00255-1.4	M244N	Pathogenic	0.999
MEN1	O00255-1.4	M244P	Pathogenic	0.996
MEN1	O00255-1.4	M244Q	Pathogenic	0.995
MEN1	O00255-1.4	M244R	Pathogenic	0.999
MEN1	O00255-1.4	M244S	Pathogenic	1.0
MEN1	O00255-1.4	M244T	Pathogenic	0.998
MEN1	O00255-1.4	M244V	Pathogenic	0.971
MEN1	O00255-1.4	M244W	Pathogenic	0.999
MEN1	O00255-1.4	M244Y	Pathogenic	0.98
MEN1	O00255-1.4	V245A	Pathogenic	0.999
MEN1	O00255-1.4	V245C	Pathogenic	0.989
MEN1	O00255-1.4	V245D	Pathogenic	0.999
MEN1	O00255-1.4	V245E	Pathogenic	0.998
MEN1	O00255-1.4	V245F	Pathogenic	0.997
MEN1	O00255-1.4	V245G	Pathogenic	1.0
MEN1	O00255-1.4	V245H	Pathogenic	0.996
MEN1	O00255-1.4	V245I	Pathogenic	0.992
MEN1	O00255-1.4	V245K	Pathogenic	1.0
MEN1	O00255-1.4	V245L	Pathogenic	0.992
MEN1	O00255-1.4	V245M	Pathogenic	0.983
MEN1	O00255-1.4	V245N	Pathogenic	0.998
MEN1	O00255-1.4	V245P	Pathogenic	0.991
MEN1	O00255-1.4	V245Q	Pathogenic	0.997
MEN1	O00255-1.4	V245R	Pathogenic	1.0
MEN1	O00255-1.4	V245S	Pathogenic	0.999
MEN1	O00255-1.4	V245T	Pathogenic	0.994
MEN1	O00255-1.4	V245W	Pathogenic	1.0
MEN1	O00255-1.4	V245Y	Pathogenic	0.997
MEN1	O00255-1.4	C246A	Pathogenic	0.997
MEN1	O00255-1.4	C246D	Pathogenic	0.999
MEN1	O00255-1.4	C246E	Pathogenic	1.0
MEN1	O00255-1.4	C246F	Pathogenic	1.0
MEN1	O00255-1.4	C246G	Pathogenic	1.0
MEN1	O00255-1.4	C246H	Pathogenic	0.999
MEN1	O00255-1.4	C246I	Pathogenic	1.0
MEN1	O00255-1.4	C246K	Pathogenic	1.0
MEN1	O00255-1.4	C246L	Pathogenic	0.999
MEN1	O00255-1.4	C246M	Pathogenic	0.999
MEN1	O00255-1.4	C246N	Pathogenic	0.999
MEN1	O00255-1.4	C246P	Pathogenic	0.987
MEN1	O00255-1.4	C246Q	Pathogenic	1.0
MEN1	O00255-1.4	C246R	Pathogenic	1.0
MEN1	O00255-1.4	C246S	Pathogenic	0.998
MEN1	O00255-1.4	C246T	Pathogenic	0.995
MEN1	O00255-1.4	C246V	Pathogenic	0.995
MEN1	O00255-1.4	C246W	Pathogenic	1.0
MEN1	O00255-1.4	C246Y	Pathogenic	1.0
MEN1	O00255-1.4	A247C	Pathogenic	0.988
MEN1	O00255-1.4	A247D	Pathogenic	0.996
MEN1	O00255-1.4	A247E	Pathogenic	0.999
MEN1	O00255-1.4	A247F	Pathogenic	1.0
MEN1	O00255-1.4	A247G	Pathogenic	0.978
MEN1	O00255-1.4	A247H	Pathogenic	0.998
MEN1	O00255-1.4	A247I	Pathogenic	1.0
MEN1	O00255-1.4	A247K	Pathogenic	1.0
MEN1	O00255-1.4	A247L	Pathogenic	1.0
MEN1	O00255-1.4	A247M	Pathogenic	1.0
MEN1	O00255-1.4	A247N	Pathogenic	0.996
MEN1	O00255-1.4	A247P	Pathogenic	0.987
MEN1	O00255-1.4	A247Q	Pathogenic	0.998
MEN1	O00255-1.4	A247R	Pathogenic	1.0
MEN1	O00255-1.4	A247S	Pathogenic	0.943
MEN1	O00255-1.4	A247T	Pathogenic	0.98
MEN1	O00255-1.4	A247V	Pathogenic	0.998
MEN1	O00255-1.4	A247W	Pathogenic	1.0
MEN1	O00255-1.4	A247Y	Pathogenic	1.0
MEN1	O00255-1.4	I248A	Pathogenic	1.0
MEN1	O00255-1.4	I248C	Pathogenic	1.0
MEN1	O00255-1.4	I248D	Pathogenic	1.0
MEN1	O00255-1.4	I248E	Pathogenic	1.0
MEN1	O00255-1.4	I248F	Pathogenic	0.99
MEN1	O00255-1.4	I248G	Pathogenic	1.0
MEN1	O00255-1.4	I248H	Pathogenic	0.999
MEN1	O00255-1.4	I248K	Pathogenic	1.0
MEN1	O00255-1.4	I248L	Pathogenic	0.978
MEN1	O00255-1.4	I248M	Pathogenic	0.99
MEN1	O00255-1.4	I248N	Pathogenic	1.0
MEN1	O00255-1.4	I248P	Pathogenic	1.0
MEN1	O00255-1.4	I248Q	Pathogenic	1.0
MEN1	O00255-1.4	I248R	Pathogenic	1.0
MEN1	O00255-1.4	I248S	Pathogenic	1.0
MEN1	O00255-1.4	I248T	Pathogenic	1.0
MEN1	O00255-1.4	I248V	Pathogenic	0.997
MEN1	O00255-1.4	I248W	Pathogenic	0.999
MEN1	O00255-1.4	I248Y	Pathogenic	0.998
MEN1	O00255-1.4	N249A	Pathogenic	1.0
MEN1	O00255-1.4	N249C	Pathogenic	1.0
MEN1	O00255-1.4	N249D	Pathogenic	0.996
MEN1	O00255-1.4	N249E	Pathogenic	0.998
MEN1	O00255-1.4	N249F	Pathogenic	1.0
MEN1	O00255-1.4	N249G	Pathogenic	1.0
MEN1	O00255-1.4	N249H	Pathogenic	1.0
MEN1	O00255-1.4	N249I	Pathogenic	1.0
MEN1	O00255-1.4	N249K	Pathogenic	1.0
MEN1	O00255-1.4	N249L	Pathogenic	1.0
MEN1	O00255-1.4	N249M	Pathogenic	1.0
MEN1	O00255-1.4	N249P	Pathogenic	1.0
MEN1	O00255-1.4	N249Q	Pathogenic	0.999
MEN1	O00255-1.4	N249R	Pathogenic	1.0
MEN1	O00255-1.4	N249S	Pathogenic	0.999
MEN1	O00255-1.4	N249T	Pathogenic	0.999
MEN1	O00255-1.4	N249V	Pathogenic	1.0
MEN1	O00255-1.4	N249W	Pathogenic	1.0
MEN1	O00255-1.4	N249Y	Pathogenic	1.0
MEN1	O00255-1.4	P250A	Pathogenic	0.989
MEN1	O00255-1.4	P250C	Pathogenic	0.952
MEN1	O00255-1.4	P250D	Pathogenic	0.99
MEN1	O00255-1.4	P250E	Pathogenic	0.997
MEN1	O00255-1.4	P250F	Pathogenic	0.999
MEN1	O00255-1.4	P250G	Pathogenic	0.998
MEN1	O00255-1.4	P250H	Pathogenic	0.995
MEN1	O00255-1.4	P250I	Pathogenic	0.999
MEN1	O00255-1.4	P250K	Pathogenic	1.0
MEN1	O00255-1.4	P250L	Pathogenic	0.998
MEN1	O00255-1.4	P250M	Pathogenic	0.996
MEN1	O00255-1.4	P250N	Pathogenic	0.992
MEN1	O00255-1.4	P250Q	Pathogenic	0.996
MEN1	O00255-1.4	P250R	Pathogenic	1.0
MEN1	O00255-1.4	P250S	Pathogenic	0.99
MEN1	O00255-1.4	P250T	Pathogenic	0.957
MEN1	O00255-1.4	P250V	Pathogenic	0.984
MEN1	O00255-1.4	P250W	Pathogenic	1.0
MEN1	O00255-1.4	P250Y	Pathogenic	0.998
MEN1	O00255-1.4	S251A	Pathogenic	0.881
MEN1	O00255-1.4	S251C	Pathogenic	0.977
MEN1	O00255-1.4	S251D	Pathogenic	0.973
MEN1	O00255-1.4	S251E	Pathogenic	0.991
MEN1	O00255-1.4	S251F	Pathogenic	1.0
MEN1	O00255-1.4	S251G	Pathogenic	0.952
MEN1	O00255-1.4	S251H	Pathogenic	0.991
MEN1	O00255-1.4	S251I	Pathogenic	1.0
MEN1	O00255-1.4	S251K	Pathogenic	0.999
MEN1	O00255-1.4	S251L	Pathogenic	1.0
MEN1	O00255-1.4	S251M	Pathogenic	0.999
MEN1	O00255-1.4	S251N	Pathogenic	0.974
MEN1	O00255-1.4	S251P	Pathogenic	0.974
MEN1	O00255-1.4	S251Q	Pathogenic	0.988
MEN1	O00255-1.4	S251R	Pathogenic	1.0
MEN1	O00255-1.4	S251T	Pathogenic	0.951
MEN1	O00255-1.4	S251V	Pathogenic	0.996
MEN1	O00255-1.4	S251W	Pathogenic	1.0
MEN1	O00255-1.4	S251Y	Pathogenic	1.0
MEN1	O00255-1.4	I252A	Pathogenic	1.0
MEN1	O00255-1.4	I252C	Pathogenic	0.994
MEN1	O00255-1.4	I252D	Pathogenic	1.0
MEN1	O00255-1.4	I252E	Pathogenic	0.998
MEN1	O00255-1.4	I252F	Pathogenic	0.847
MEN1	O00255-1.4	I252G	Pathogenic	1.0
MEN1	O00255-1.4	I252H	Pathogenic	0.985
MEN1	O00255-1.4	I252K	Pathogenic	0.998
MEN1	O00255-1.4	I252L	Pathogenic	0.714
MEN1	O00255-1.4	I252M	Pathogenic	0.85
MEN1	O00255-1.4	I252N	Pathogenic	0.999
MEN1	O00255-1.4	I252P	Pathogenic	0.995
MEN1	O00255-1.4	I252Q	Pathogenic	0.994
MEN1	O00255-1.4	I252R	Pathogenic	0.999
MEN1	O00255-1.4	I252S	Pathogenic	1.0
MEN1	O00255-1.4	I252T	Pathogenic	0.997
MEN1	O00255-1.4	I252V	Pathogenic	0.955
MEN1	O00255-1.4	I252W	Pathogenic	0.991
MEN1	O00255-1.4	I252Y	Pathogenic	0.972
MEN1	O00255-1.4	D253A	Pathogenic	0.962
MEN1	O00255-1.4	D253C	Pathogenic	0.951
MEN1	O00255-1.4	D253E	Pathogenic	0.731
MEN1	O00255-1.4	D253F	Pathogenic	0.999
MEN1	O00255-1.4	D253G	Pathogenic	0.983
MEN1	O00255-1.4	D253H	Pathogenic	0.957
MEN1	O00255-1.4	D253I	Pathogenic	0.998
MEN1	O00255-1.4	D253K	Pathogenic	0.963
MEN1	O00255-1.4	D253L	Pathogenic	0.998
MEN1	O00255-1.4	D253M	Pathogenic	0.996
MEN1	O00255-1.4	D253N	Pathogenic	0.537
MEN1	O00255-1.4	D253P	Pathogenic	0.892
MEN1	O00255-1.4	D253Q	Pathogenic	0.898
MEN1	O00255-1.4	D253R	Pathogenic	0.987
MEN1	O00255-1.4	D253S	Pathogenic	0.89
MEN1	O00255-1.4	D253T	Pathogenic	0.808
MEN1	O00255-1.4	D253V	Pathogenic	0.982
MEN1	O00255-1.4	D253W	Pathogenic	1.0
MEN1	O00255-1.4	D253Y	Pathogenic	0.998
MEN1	O00255-1.4	L254A	Pathogenic	0.98
MEN1	O00255-1.4	L254C	Pathogenic	0.802
MEN1	O00255-1.4	L254D	Pathogenic	0.983
MEN1	O00255-1.4	L254E	Pathogenic	0.919
MEN1	O00255-1.4	L254F	Neutral	0.155
MEN1	O00255-1.4	L254G	Pathogenic	0.998
MEN1	O00255-1.4	L254H	Pathogenic	0.625
MEN1	O00255-1.4	L254I	Neutral	0.068
MEN1	O00255-1.4	L254K	Pathogenic	0.934
MEN1	O00255-1.4	L254M	Neutral	0.117
MEN1	O00255-1.4	L254N	Pathogenic	0.966
MEN1	O00255-1.4	L254P	Pathogenic	0.839
MEN1	O00255-1.4	L254Q	Pathogenic	0.789
MEN1	O00255-1.4	L254R	Pathogenic	0.974
MEN1	O00255-1.4	L254S	Pathogenic	0.983
MEN1	O00255-1.4	L254T	Pathogenic	0.886
MEN1	O00255-1.4	L254V	Neutral	0.373
MEN1	O00255-1.4	L254W	Pathogenic	0.779
MEN1	O00255-1.4	L254Y	Neutral	0.467
MEN1	O00255-1.4	H255A	Pathogenic	0.998
MEN1	O00255-1.4	H255C	Pathogenic	0.997
MEN1	O00255-1.4	H255D	Pathogenic	0.995
MEN1	O00255-1.4	H255E	Pathogenic	0.977
MEN1	O00255-1.4	H255F	Pathogenic	0.997
MEN1	O00255-1.4	H255G	Pathogenic	0.999
MEN1	O00255-1.4	H255I	Pathogenic	0.994
MEN1	O00255-1.4	H255K	Pathogenic	0.993
MEN1	O00255-1.4	H255L	Pathogenic	0.993
MEN1	O00255-1.4	H255M	Pathogenic	0.985
MEN1	O00255-1.4	H255N	Pathogenic	0.99
MEN1	O00255-1.4	H255P	Pathogenic	0.993
MEN1	O00255-1.4	H255Q	Pathogenic	0.936
MEN1	O00255-1.4	H255R	Pathogenic	0.997
MEN1	O00255-1.4	H255S	Pathogenic	0.996
MEN1	O00255-1.4	H255T	Pathogenic	0.982
MEN1	O00255-1.4	H255V	Pathogenic	0.991
MEN1	O00255-1.4	H255W	Pathogenic	1.0
MEN1	O00255-1.4	H255Y	Pathogenic	0.991
MEN1	O00255-1.4	T256A	Pathogenic	0.874
MEN1	O00255-1.4	T256C	Pathogenic	0.841
MEN1	O00255-1.4	T256D	Pathogenic	0.856
MEN1	O00255-1.4	T256E	Pathogenic	0.932
MEN1	O00255-1.4	T256F	Pathogenic	0.996
MEN1	O00255-1.4	T256G	Pathogenic	0.978
MEN1	O00255-1.4	T256H	Pathogenic	0.891
MEN1	O00255-1.4	T256I	Pathogenic	0.992
MEN1	O00255-1.4	T256K	Pathogenic	0.994
MEN1	O00255-1.4	T256L	Pathogenic	0.99
MEN1	O00255-1.4	T256M	Pathogenic	0.979
MEN1	O00255-1.4	T256N	Pathogenic	0.821
MEN1	O00255-1.4	T256P	Pathogenic	0.719
MEN1	O00255-1.4	T256Q	Pathogenic	0.91
MEN1	O00255-1.4	T256R	Pathogenic	0.998
MEN1	O00255-1.4	T256S	Pathogenic	0.86
MEN1	O00255-1.4	T256V	Pathogenic	0.914
MEN1	O00255-1.4	T256W	Pathogenic	1.0
MEN1	O00255-1.4	T256Y	Pathogenic	0.991
MEN1	O00255-1.4	D257A	Pathogenic	0.998
MEN1	O00255-1.4	D257C	Pathogenic	0.998
MEN1	O00255-1.4	D257E	Pathogenic	0.985
MEN1	O00255-1.4	D257F	Pathogenic	1.0
MEN1	O00255-1.4	D257G	Pathogenic	0.999
MEN1	O00255-1.4	D257H	Pathogenic	0.998
MEN1	O00255-1.4	D257I	Pathogenic	1.0
MEN1	O00255-1.4	D257K	Pathogenic	0.998
MEN1	O00255-1.4	D257L	Pathogenic	1.0
MEN1	O00255-1.4	D257M	Pathogenic	1.0
MEN1	O00255-1.4	D257N	Pathogenic	0.966
MEN1	O00255-1.4	D257P	Pathogenic	0.995
MEN1	O00255-1.4	D257Q	Pathogenic	0.995
MEN1	O00255-1.4	D257R	Pathogenic	0.999
MEN1	O00255-1.4	D257S	Pathogenic	0.995
MEN1	O00255-1.4	D257T	Pathogenic	0.99
MEN1	O00255-1.4	D257V	Pathogenic	0.999
MEN1	O00255-1.4	D257W	Pathogenic	1.0
MEN1	O00255-1.4	D257Y	Pathogenic	1.0
MEN1	O00255-1.4	S258A	Pathogenic	0.839
MEN1	O00255-1.4	S258C	Pathogenic	0.967
MEN1	O00255-1.4	S258D	Pathogenic	0.962
MEN1	O00255-1.4	S258E	Pathogenic	0.988
MEN1	O00255-1.4	S258F	Pathogenic	1.0
MEN1	O00255-1.4	S258G	Pathogenic	0.933
MEN1	O00255-1.4	S258H	Pathogenic	0.988
MEN1	O00255-1.4	S258I	Pathogenic	1.0
MEN1	O00255-1.4	S258K	Pathogenic	0.999
MEN1	O00255-1.4	S258L	Pathogenic	0.999
MEN1	O00255-1.4	S258M	Pathogenic	0.999
MEN1	O00255-1.4	S258N	Pathogenic	0.964
MEN1	O00255-1.4	S258P	Pathogenic	0.963
MEN1	O00255-1.4	S258Q	Pathogenic	0.983
MEN1	O00255-1.4	S258R	Pathogenic	1.0
MEN1	O00255-1.4	S258T	Pathogenic	0.932
MEN1	O00255-1.4	S258V	Pathogenic	0.995
MEN1	O00255-1.4	S258W	Pathogenic	1.0
MEN1	O00255-1.4	S258Y	Pathogenic	0.999
MEN1	O00255-1.4	L259A	Pathogenic	0.923
MEN1	O00255-1.4	L259C	Neutral	0.494
MEN1	O00255-1.4	L259D	Pathogenic	0.932
MEN1	O00255-1.4	L259E	Pathogenic	0.732
MEN1	O00255-1.4	L259F	Neutral	0.042
MEN1	O00255-1.4	L259G	Pathogenic	0.99
MEN1	O00255-1.4	L259H	Neutral	0.286
MEN1	O00255-1.4	L259I	Neutral	0.017
MEN1	O00255-1.4	L259K	Pathogenic	0.772
MEN1	O00255-1.4	L259M	Neutral	0.031
MEN1	O00255-1.4	L259N	Pathogenic	0.872
MEN1	O00255-1.4	L259P	Pathogenic	0.556
MEN1	O00255-1.4	L259Q	Neutral	0.474
MEN1	O00255-1.4	L259R	Pathogenic	0.901
MEN1	O00255-1.4	L259S	Pathogenic	0.935
MEN1	O00255-1.4	L259T	Pathogenic	0.653
MEN1	O00255-1.4	L259V	Neutral	0.125
MEN1	O00255-1.4	L259W	Neutral	0.459
MEN1	O00255-1.4	L259Y	Neutral	0.174
MEN1	O00255-1.4	E260A	Pathogenic	0.999
MEN1	O00255-1.4	E260C	Pathogenic	0.999
MEN1	O00255-1.4	E260D	Pathogenic	0.971
MEN1	O00255-1.4	E260F	Pathogenic	1.0
MEN1	O00255-1.4	E260G	Pathogenic	1.0
MEN1	O00255-1.4	E260H	Pathogenic	0.982
MEN1	O00255-1.4	E260I	Pathogenic	0.999
MEN1	O00255-1.4	E260K	Pathogenic	0.989
MEN1	O00255-1.4	E260L	Pathogenic	0.999
MEN1	O00255-1.4	E260M	Pathogenic	0.998
MEN1	O00255-1.4	E260N	Pathogenic	0.957
MEN1	O00255-1.4	E260P	Pathogenic	0.997
MEN1	O00255-1.4	E260Q	Pathogenic	0.953
MEN1	O00255-1.4	E260R	Pathogenic	0.996
MEN1	O00255-1.4	E260S	Pathogenic	0.997
MEN1	O00255-1.4	E260T	Pathogenic	0.992
MEN1	O00255-1.4	E260V	Pathogenic	0.996
MEN1	O00255-1.4	E260W	Pathogenic	1.0
MEN1	O00255-1.4	E260Y	Pathogenic	0.999
MEN1	O00255-1.4	L261A	Pathogenic	0.997
MEN1	O00255-1.4	L261C	Pathogenic	0.96
MEN1	O00255-1.4	L261D	Pathogenic	0.997
MEN1	O00255-1.4	L261E	Pathogenic	0.985
MEN1	O00255-1.4	L261F	Pathogenic	0.521
MEN1	O00255-1.4	L261G	Pathogenic	1.0
MEN1	O00255-1.4	L261H	Pathogenic	0.908
MEN1	O00255-1.4	L261I	Neutral	0.303
MEN1	O00255-1.4	L261K	Pathogenic	0.988
MEN1	O00255-1.4	L261M	Neutral	0.44
MEN1	O00255-1.4	L261N	Pathogenic	0.994
MEN1	O00255-1.4	L261P	Pathogenic	0.969
MEN1	O00255-1.4	L261Q	Pathogenic	0.957
MEN1	O00255-1.4	L261R	Pathogenic	0.996
MEN1	O00255-1.4	L261S	Pathogenic	0.997
MEN1	O00255-1.4	L261T	Pathogenic	0.979
MEN1	O00255-1.4	L261V	Pathogenic	0.779
MEN1	O00255-1.4	L261W	Pathogenic	0.955
MEN1	O00255-1.4	L261Y	Pathogenic	0.839
MEN1	O00255-1.4	L262A	Pathogenic	0.984
MEN1	O00255-1.4	L262C	Pathogenic	0.836
MEN1	O00255-1.4	L262D	Pathogenic	0.986
MEN1	O00255-1.4	L262E	Pathogenic	0.935
MEN1	O00255-1.4	L262F	Neutral	0.187
MEN1	O00255-1.4	L262G	Pathogenic	0.998
MEN1	O00255-1.4	L262H	Pathogenic	0.677
MEN1	O00255-1.4	L262I	Neutral	0.084
MEN1	O00255-1.4	L262K	Pathogenic	0.946
MEN1	O00255-1.4	L262M	Neutral	0.143
MEN1	O00255-1.4	L262N	Pathogenic	0.973
MEN1	O00255-1.4	L262P	Pathogenic	0.868
MEN1	O00255-1.4	L262Q	Pathogenic	0.825
MEN1	O00255-1.4	L262R	Pathogenic	0.98
MEN1	O00255-1.4	L262S	Pathogenic	0.987
MEN1	O00255-1.4	L262T	Pathogenic	0.908
MEN1	O00255-1.4	L262V	Neutral	0.428
MEN1	O00255-1.4	L262W	Pathogenic	0.816
MEN1	O00255-1.4	L262Y	Pathogenic	0.524
MEN1	O00255-1.4	Q263A	Pathogenic	0.96
MEN1	O00255-1.4	Q263C	Pathogenic	0.951
MEN1	O00255-1.4	Q263D	Pathogenic	0.794
MEN1	O00255-1.4	Q263E	Neutral	0.419
MEN1	O00255-1.4	Q263F	Pathogenic	0.977
MEN1	O00255-1.4	Q263G	Pathogenic	0.984
MEN1	O00255-1.4	Q263H	Neutral	0.404
MEN1	O00255-1.4	Q263I	Pathogenic	0.95
MEN1	O00255-1.4	Q263K	Pathogenic	0.817
MEN1	O00255-1.4	Q263L	Pathogenic	0.938
MEN1	O00255-1.4	Q263M	Pathogenic	0.863
MEN1	O00255-1.4	Q263N	Pathogenic	0.669
MEN1	O00255-1.4	Q263P	Pathogenic	0.893
MEN1	O00255-1.4	Q263R	Pathogenic	0.924
MEN1	O00255-1.4	Q263S	Pathogenic	0.891
MEN1	O00255-1.4	Q263T	Pathogenic	0.758
MEN1	O00255-1.4	Q263V	Pathogenic	0.866
MEN1	O00255-1.4	Q263W	Pathogenic	0.999
MEN1	O00255-1.4	Q263Y	Pathogenic	0.939
MEN1	O00255-1.4	L264A	Pathogenic	0.999
MEN1	O00255-1.4	L264C	Pathogenic	0.992
MEN1	O00255-1.4	L264D	Pathogenic	0.999
MEN1	O00255-1.4	L264E	Pathogenic	0.997
MEN1	O00255-1.4	L264F	Pathogenic	0.855
MEN1	O00255-1.4	L264G	Pathogenic	1.0
MEN1	O00255-1.4	L264H	Pathogenic	0.982
MEN1	O00255-1.4	L264I	Pathogenic	0.701
MEN1	O00255-1.4	L264K	Pathogenic	0.998
MEN1	O00255-1.4	L264M	Pathogenic	0.81
MEN1	O00255-1.4	L264N	Pathogenic	0.999
MEN1	O00255-1.4	L264P	Pathogenic	0.994
MEN1	O00255-1.4	L264Q	Pathogenic	0.992
MEN1	O00255-1.4	L264R	Pathogenic	0.999
MEN1	O00255-1.4	L264S	Pathogenic	0.999
MEN1	O00255-1.4	L264T	Pathogenic	0.996
MEN1	O00255-1.4	L264V	Pathogenic	0.95
MEN1	O00255-1.4	L264W	Pathogenic	0.991
MEN1	O00255-1.4	L264Y	Pathogenic	0.966
MEN1	O00255-1.4	Q265A	Pathogenic	1.0
MEN1	O00255-1.4	Q265C	Pathogenic	1.0
MEN1	O00255-1.4	Q265D	Pathogenic	0.998
MEN1	O00255-1.4	Q265E	Pathogenic	0.99
MEN1	O00255-1.4	Q265F	Pathogenic	1.0
MEN1	O00255-1.4	Q265G	Pathogenic	1.0
MEN1	O00255-1.4	Q265H	Pathogenic	0.989
MEN1	O00255-1.4	Q265I	Pathogenic	1.0
MEN1	O00255-1.4	Q265K	Pathogenic	0.998
MEN1	O00255-1.4	Q265L	Pathogenic	1.0
MEN1	O00255-1.4	Q265M	Pathogenic	0.999
MEN1	O00255-1.4	Q265N	Pathogenic	0.996
MEN1	O00255-1.4	Q265P	Pathogenic	0.999
MEN1	O00255-1.4	Q265R	Pathogenic	0.999
MEN1	O00255-1.4	Q265S	Pathogenic	0.999
MEN1	O00255-1.4	Q265T	Pathogenic	0.998
MEN1	O00255-1.4	Q265V	Pathogenic	0.999
MEN1	O00255-1.4	Q265W	Pathogenic	1.0
MEN1	O00255-1.4	Q265Y	Pathogenic	1.0
MEN1	O00255-1.4	Q266A	Pathogenic	1.0
MEN1	O00255-1.4	Q266C	Pathogenic	1.0
MEN1	O00255-1.4	Q266D	Pathogenic	0.998
MEN1	O00255-1.4	Q266E	Pathogenic	0.987
MEN1	O00255-1.4	Q266F	Pathogenic	1.0
MEN1	O00255-1.4	Q266G	Pathogenic	1.0
MEN1	O00255-1.4	Q266H	Pathogenic	0.986
MEN1	O00255-1.4	Q266I	Pathogenic	1.0
MEN1	O00255-1.4	Q266K	Pathogenic	0.998
MEN1	O00255-1.4	Q266L	Pathogenic	0.999
MEN1	O00255-1.4	Q266M	Pathogenic	0.998
MEN1	O00255-1.4	Q266N	Pathogenic	0.995
MEN1	O00255-1.4	Q266P	Pathogenic	0.999
MEN1	O00255-1.4	Q266R	Pathogenic	0.999
MEN1	O00255-1.4	Q266S	Pathogenic	0.999
MEN1	O00255-1.4	Q266T	Pathogenic	0.997
MEN1	O00255-1.4	Q266V	Pathogenic	0.999
MEN1	O00255-1.4	Q266W	Pathogenic	1.0
MEN1	O00255-1.4	Q266Y	Pathogenic	0.999
MEN1	O00255-1.4	K267A	Pathogenic	0.993
MEN1	O00255-1.4	K267C	Pathogenic	0.991
MEN1	O00255-1.4	K267D	Pathogenic	0.805
MEN1	O00255-1.4	K267E	Pathogenic	0.542
MEN1	O00255-1.4	K267F	Pathogenic	0.917
MEN1	O00255-1.4	K267G	Pathogenic	0.997
MEN1	O00255-1.4	K267H	Pathogenic	0.704
MEN1	O00255-1.4	K267I	Pathogenic	0.963
MEN1	O00255-1.4	K267L	Pathogenic	0.954
MEN1	O00255-1.4	K267M	Pathogenic	0.9
MEN1	O00255-1.4	K267N	Pathogenic	0.779
MEN1	O00255-1.4	K267P	Pathogenic	0.98
MEN1	O00255-1.4	K267Q	Pathogenic	0.616
MEN1	O00255-1.4	K267R	Neutral	0.196
MEN1	O00255-1.4	K267S	Pathogenic	0.98
MEN1	O00255-1.4	K267T	Pathogenic	0.949
MEN1	O00255-1.4	K267V	Pathogenic	0.975
MEN1	O00255-1.4	K267W	Pathogenic	0.995
MEN1	O00255-1.4	K267Y	Pathogenic	0.81
MEN1	O00255-1.4	L268A	Pathogenic	1.0
MEN1	O00255-1.4	L268C	Pathogenic	0.996
MEN1	O00255-1.4	L268D	Pathogenic	1.0
MEN1	O00255-1.4	L268E	Pathogenic	0.999
MEN1	O00255-1.4	L268F	Pathogenic	0.927
MEN1	O00255-1.4	L268G	Pathogenic	1.0
MEN1	O00255-1.4	L268H	Pathogenic	0.991
MEN1	O00255-1.4	L268I	Pathogenic	0.835
MEN1	O00255-1.4	L268K	Pathogenic	0.999
MEN1	O00255-1.4	L268M	Pathogenic	0.902
MEN1	O00255-1.4	L268N	Pathogenic	0.999
MEN1	O00255-1.4	L268P	Pathogenic	0.997
MEN1	O00255-1.4	L268Q	Pathogenic	0.996
MEN1	O00255-1.4	L268R	Pathogenic	1.0
MEN1	O00255-1.4	L268S	Pathogenic	1.0
MEN1	O00255-1.4	L268T	Pathogenic	0.998
MEN1	O00255-1.4	L268V	Pathogenic	0.976
MEN1	O00255-1.4	L268W	Pathogenic	0.996
MEN1	O00255-1.4	L268Y	Pathogenic	0.984
MEN1	O00255-1.4	L269A	Pathogenic	1.0
MEN1	O00255-1.4	L269C	Pathogenic	0.996
MEN1	O00255-1.4	L269D	Pathogenic	1.0
MEN1	O00255-1.4	L269E	Pathogenic	0.999
MEN1	O00255-1.4	L269F	Pathogenic	0.927
MEN1	O00255-1.4	L269G	Pathogenic	1.0
MEN1	O00255-1.4	L269H	Pathogenic	0.991
MEN1	O00255-1.4	L269I	Pathogenic	0.835
MEN1	O00255-1.4	L269K	Pathogenic	0.999
MEN1	O00255-1.4	L269M	Pathogenic	0.902
MEN1	O00255-1.4	L269N	Pathogenic	0.999
MEN1	O00255-1.4	L269P	Pathogenic	0.997
MEN1	O00255-1.4	L269Q	Pathogenic	0.996
MEN1	O00255-1.4	L269R	Pathogenic	1.0
MEN1	O00255-1.4	L269S	Pathogenic	1.0
MEN1	O00255-1.4	L269T	Pathogenic	0.998
MEN1	O00255-1.4	L269V	Pathogenic	0.976
MEN1	O00255-1.4	L269W	Pathogenic	0.996
MEN1	O00255-1.4	L269Y	Pathogenic	0.984
MEN1	O00255-1.4	W270A	Pathogenic	1.0
MEN1	O00255-1.4	W270C	Pathogenic	1.0
MEN1	O00255-1.4	W270D	Pathogenic	1.0
MEN1	O00255-1.4	W270E	Pathogenic	1.0
MEN1	O00255-1.4	W270F	Pathogenic	1.0
MEN1	O00255-1.4	W270G	Pathogenic	1.0
MEN1	O00255-1.4	W270H	Pathogenic	1.0
MEN1	O00255-1.4	W270I	Pathogenic	1.0
MEN1	O00255-1.4	W270K	Pathogenic	1.0
MEN1	O00255-1.4	W270L	Pathogenic	1.0
MEN1	O00255-1.4	W270M	Pathogenic	1.0
MEN1	O00255-1.4	W270N	Pathogenic	1.0
MEN1	O00255-1.4	W270P	Pathogenic	1.0
MEN1	O00255-1.4	W270Q	Pathogenic	1.0
MEN1	O00255-1.4	W270R	Pathogenic	1.0
MEN1	O00255-1.4	W270S	Pathogenic	1.0
MEN1	O00255-1.4	W270T	Pathogenic	1.0
MEN1	O00255-1.4	W270V	Pathogenic	1.0
MEN1	O00255-1.4	W270Y	Pathogenic	1.0
MEN1	O00255-1.4	L271A	Pathogenic	0.998
MEN1	O00255-1.4	L271C	Pathogenic	0.973
MEN1	O00255-1.4	L271D	Pathogenic	0.998
MEN1	O00255-1.4	L271E	Pathogenic	0.99
MEN1	O00255-1.4	L271F	Pathogenic	0.616
MEN1	O00255-1.4	L271G	Pathogenic	1.0
MEN1	O00255-1.4	L271H	Pathogenic	0.936
MEN1	O00255-1.4	L271I	Neutral	0.39
MEN1	O00255-1.4	L271K	Pathogenic	0.992
MEN1	O00255-1.4	L271M	Pathogenic	0.537
MEN1	O00255-1.4	L271N	Pathogenic	0.996
MEN1	O00255-1.4	L271P	Pathogenic	0.979
MEN1	O00255-1.4	L271Q	Pathogenic	0.97
MEN1	O00255-1.4	L271R	Pathogenic	0.997
MEN1	O00255-1.4	L271S	Pathogenic	0.998
MEN1	O00255-1.4	L271T	Pathogenic	0.986
MEN1	O00255-1.4	L271V	Pathogenic	0.839
MEN1	O00255-1.4	L271W	Pathogenic	0.969
MEN1	O00255-1.4	L271Y	Pathogenic	0.885
MEN1	O00255-1.4	L272A	Pathogenic	1.0
MEN1	O00255-1.4	L272C	Pathogenic	0.997
MEN1	O00255-1.4	L272D	Pathogenic	1.0
MEN1	O00255-1.4	L272E	Pathogenic	0.999
MEN1	O00255-1.4	L272F	Pathogenic	0.946
MEN1	O00255-1.4	L272G	Pathogenic	1.0
MEN1	O00255-1.4	L272H	Pathogenic	0.994
MEN1	O00255-1.4	L272I	Pathogenic	0.874
MEN1	O00255-1.4	L272K	Pathogenic	0.999
MEN1	O00255-1.4	L272M	Pathogenic	0.926
MEN1	O00255-1.4	L272N	Pathogenic	1.0
MEN1	O00255-1.4	L272P	Pathogenic	0.998
MEN1	O00255-1.4	L272Q	Pathogenic	0.997
MEN1	O00255-1.4	L272R	Pathogenic	1.0
MEN1	O00255-1.4	L272S	Pathogenic	1.0
MEN1	O00255-1.4	L272T	Pathogenic	0.999
MEN1	O00255-1.4	L272V	Pathogenic	0.983
MEN1	O00255-1.4	L272W	Pathogenic	0.997
MEN1	O00255-1.4	L272Y	Pathogenic	0.988
MEN1	O00255-1.4	Y273A	Pathogenic	1.0
MEN1	O00255-1.4	Y273C	Pathogenic	1.0
MEN1	O00255-1.4	Y273D	Pathogenic	1.0
MEN1	O00255-1.4	Y273E	Pathogenic	1.0
MEN1	O00255-1.4	Y273F	Pathogenic	0.996
MEN1	O00255-1.4	Y273G	Pathogenic	1.0
MEN1	O00255-1.4	Y273H	Pathogenic	0.999
MEN1	O00255-1.4	Y273I	Pathogenic	0.999
MEN1	O00255-1.4	Y273K	Pathogenic	0.999
MEN1	O00255-1.4	Y273L	Pathogenic	0.998
MEN1	O00255-1.4	Y273M	Pathogenic	0.996
MEN1	O00255-1.4	Y273N	Pathogenic	1.0
MEN1	O00255-1.4	Y273P	Pathogenic	1.0
MEN1	O00255-1.4	Y273Q	Pathogenic	1.0
MEN1	O00255-1.4	Y273R	Pathogenic	1.0
MEN1	O00255-1.4	Y273S	Pathogenic	1.0
MEN1	O00255-1.4	Y273T	Pathogenic	1.0
MEN1	O00255-1.4	Y273V	Pathogenic	0.999
MEN1	O00255-1.4	Y273W	Pathogenic	0.999
MEN1	O00255-1.4	D274A	Pathogenic	0.996
MEN1	O00255-1.4	D274C	Pathogenic	0.994
MEN1	O00255-1.4	D274E	Pathogenic	0.962
MEN1	O00255-1.4	D274F	Pathogenic	1.0
MEN1	O00255-1.4	D274G	Pathogenic	0.998
MEN1	O00255-1.4	D274H	Pathogenic	0.995
MEN1	O00255-1.4	D274I	Pathogenic	1.0
MEN1	O00255-1.4	D274K	Pathogenic	0.996
MEN1	O00255-1.4	D274L	Pathogenic	1.0
MEN1	O00255-1.4	D274M	Pathogenic	1.0
MEN1	O00255-1.4	D274N	Pathogenic	0.915
MEN1	O00255-1.4	D274P	Pathogenic	0.987
MEN1	O00255-1.4	D274Q	Pathogenic	0.988
MEN1	O00255-1.4	D274R	Pathogenic	0.999
MEN1	O00255-1.4	D274S	Pathogenic	0.987
MEN1	O00255-1.4	D274T	Pathogenic	0.975
MEN1	O00255-1.4	D274V	Pathogenic	0.998
MEN1	O00255-1.4	D274W	Pathogenic	1.0
MEN1	O00255-1.4	D274Y	Pathogenic	1.0
MEN1	O00255-1.4	L275A	Pathogenic	0.892
MEN1	O00255-1.4	L275C	Neutral	0.401
MEN1	O00255-1.4	L275D	Pathogenic	0.905
MEN1	O00255-1.4	L275E	Pathogenic	0.653
MEN1	O00255-1.4	L275F	Neutral	0.029
MEN1	O00255-1.4	L275G	Pathogenic	0.985
MEN1	O00255-1.4	L275H	Neutral	0.216
MEN1	O00255-1.4	L275I	Neutral	0.012
MEN1	O00255-1.4	L275K	Pathogenic	0.699
MEN1	O00255-1.4	L275M	Neutral	0.021
MEN1	O00255-1.4	L275N	Pathogenic	0.824
MEN1	O00255-1.4	L275P	Neutral	0.463
MEN1	O00255-1.4	L275Q	Neutral	0.382
MEN1	O00255-1.4	L275R	Pathogenic	0.863
MEN1	O00255-1.4	L275S	Pathogenic	0.908
MEN1	O00255-1.4	L275T	Pathogenic	0.563
MEN1	O00255-1.4	L275V	Neutral	0.089
MEN1	O00255-1.4	L275W	Neutral	0.369
MEN1	O00255-1.4	L275Y	Neutral	0.126
MEN1	O00255-1.4	G276A	Pathogenic	0.968
MEN1	O00255-1.4	G276C	Pathogenic	0.998
MEN1	O00255-1.4	G276D	Pathogenic	0.998
MEN1	O00255-1.4	G276E	Pathogenic	0.999
MEN1	O00255-1.4	G276F	Pathogenic	1.0
MEN1	O00255-1.4	G276H	Pathogenic	0.999
MEN1	O00255-1.4	G276I	Pathogenic	1.0
MEN1	O00255-1.4	G276K	Pathogenic	1.0
MEN1	O00255-1.4	G276L	Pathogenic	1.0
MEN1	O00255-1.4	G276M	Pathogenic	1.0
MEN1	O00255-1.4	G276N	Pathogenic	0.998
MEN1	O00255-1.4	G276P	Pathogenic	0.997
MEN1	O00255-1.4	G276Q	Pathogenic	0.999
MEN1	O00255-1.4	G276R	Pathogenic	1.0
MEN1	O00255-1.4	G276S	Pathogenic	0.969
MEN1	O00255-1.4	G276T	Pathogenic	0.996
MEN1	O00255-1.4	G276V	Pathogenic	1.0
MEN1	O00255-1.4	G276W	Pathogenic	1.0
MEN1	O00255-1.4	G276Y	Pathogenic	1.0
MEN1	O00255-1.4	H277A	Pathogenic	0.998
MEN1	O00255-1.4	H277C	Pathogenic	0.998
MEN1	O00255-1.4	H277D	Pathogenic	0.996
MEN1	O00255-1.4	H277E	Pathogenic	0.982
MEN1	O00255-1.4	H277F	Pathogenic	0.998
MEN1	O00255-1.4	H277G	Pathogenic	1.0
MEN1	O00255-1.4	H277I	Pathogenic	0.996
MEN1	O00255-1.4	H277K	Pathogenic	0.995
MEN1	O00255-1.4	H277L	Pathogenic	0.995
MEN1	O00255-1.4	H277M	Pathogenic	0.989
MEN1	O00255-1.4	H277N	Pathogenic	0.992
MEN1	O00255-1.4	H277P	Pathogenic	0.995
MEN1	O00255-1.4	H277Q	Pathogenic	0.951
MEN1	O00255-1.4	H277R	Pathogenic	0.998
MEN1	O00255-1.4	H277S	Pathogenic	0.997
MEN1	O00255-1.4	H277T	Pathogenic	0.987
MEN1	O00255-1.4	H277V	Pathogenic	0.993
MEN1	O00255-1.4	H277W	Pathogenic	1.0
MEN1	O00255-1.4	H277Y	Pathogenic	0.994
MEN1	O00255-1.4	L278A	Pathogenic	1.0
MEN1	O00255-1.4	L278C	Pathogenic	0.994
MEN1	O00255-1.4	L278D	Pathogenic	1.0
MEN1	O00255-1.4	L278E	Pathogenic	0.998
MEN1	O00255-1.4	L278F	Pathogenic	0.883
MEN1	O00255-1.4	L278G	Pathogenic	1.0
MEN1	O00255-1.4	L278H	Pathogenic	0.986
MEN1	O00255-1.4	L278I	Pathogenic	0.751
MEN1	O00255-1.4	L278K	Pathogenic	0.998
MEN1	O00255-1.4	L278M	Pathogenic	0.845
MEN1	O00255-1.4	L278N	Pathogenic	0.999
MEN1	O00255-1.4	L278P	Pathogenic	0.995
MEN1	O00255-1.4	L278Q	Pathogenic	0.994
MEN1	O00255-1.4	L278R	Pathogenic	0.999
MEN1	O00255-1.4	L278S	Pathogenic	1.0
MEN1	O00255-1.4	L278T	Pathogenic	0.997
MEN1	O00255-1.4	L278V	Pathogenic	0.961
MEN1	O00255-1.4	L278W	Pathogenic	0.993
MEN1	O00255-1.4	L278Y	Pathogenic	0.973
MEN1	O00255-1.4	E279A	Pathogenic	0.686
MEN1	O00255-1.4	E279C	Pathogenic	0.655
MEN1	O00255-1.4	E279D	Neutral	0.075
MEN1	O00255-1.4	E279F	Pathogenic	0.892
MEN1	O00255-1.4	E279G	Pathogenic	0.854
MEN1	O00255-1.4	E279H	Neutral	0.116
MEN1	O00255-1.4	E279I	Pathogenic	0.788
MEN1	O00255-1.4	E279K	Neutral	0.183
MEN1	O00255-1.4	E279L	Pathogenic	0.759
MEN1	O00255-1.4	E279M	Pathogenic	0.581
MEN1	O00255-1.4	E279N	Neutral	0.051
MEN1	O00255-1.4	E279P	Neutral	0.433
MEN1	O00255-1.4	E279Q	Neutral	0.047
MEN1	O00255-1.4	E279R	Neutral	0.392
MEN1	O00255-1.4	E279S	Neutral	0.43
MEN1	O00255-1.4	E279T	Neutral	0.224
MEN1	O00255-1.4	E279V	Neutral	0.373
MEN1	O00255-1.4	E279W	Pathogenic	0.993
MEN1	O00255-1.4	E279Y	Pathogenic	0.76
MEN1	O00255-1.4	R280A	Pathogenic	0.999
MEN1	O00255-1.4	R280C	Pathogenic	0.999
MEN1	O00255-1.4	R280D	Pathogenic	0.984
MEN1	O00255-1.4	R280E	Pathogenic	0.945
MEN1	O00255-1.4	R280F	Pathogenic	0.993
MEN1	O00255-1.4	R280G	Pathogenic	1.0
MEN1	O00255-1.4	R280H	Pathogenic	0.968
MEN1	O00255-1.4	R280I	Pathogenic	0.997
MEN1	O00255-1.4	R280K	Pathogenic	0.552
MEN1	O00255-1.4	R280L	Pathogenic	0.996
MEN1	O00255-1.4	R280M	Pathogenic	0.992
MEN1	O00255-1.4	R280N	Pathogenic	0.98
MEN1	O00255-1.4	R280P	Pathogenic	0.999
MEN1	O00255-1.4	R280Q	Pathogenic	0.956
MEN1	O00255-1.4	R280S	Pathogenic	0.999
MEN1	O00255-1.4	R280T	Pathogenic	0.996
MEN1	O00255-1.4	R280V	Pathogenic	0.998
MEN1	O00255-1.4	R280W	Pathogenic	0.997
MEN1	O00255-1.4	R280Y	Pathogenic	0.959
MEN1	O00255-1.4	Y281A	Pathogenic	1.0
MEN1	O00255-1.4	Y281C	Pathogenic	1.0
MEN1	O00255-1.4	Y281D	Pathogenic	1.0
MEN1	O00255-1.4	Y281E	Pathogenic	1.0
MEN1	O00255-1.4	Y281F	Pathogenic	0.998
MEN1	O00255-1.4	Y281G	Pathogenic	1.0
MEN1	O00255-1.4	Y281H	Pathogenic	1.0
MEN1	O00255-1.4	Y281I	Pathogenic	0.999
MEN1	O00255-1.4	Y281K	Pathogenic	1.0
MEN1	O00255-1.4	Y281L	Pathogenic	0.999
MEN1	O00255-1.4	Y281M	Pathogenic	0.998
MEN1	O00255-1.4	Y281N	Pathogenic	1.0
MEN1	O00255-1.4	Y281P	Pathogenic	1.0
MEN1	O00255-1.4	Y281Q	Pathogenic	1.0
MEN1	O00255-1.4	Y281R	Pathogenic	1.0
MEN1	O00255-1.4	Y281S	Pathogenic	1.0
MEN1	O00255-1.4	Y281T	Pathogenic	1.0
MEN1	O00255-1.4	Y281V	Pathogenic	1.0
MEN1	O00255-1.4	Y281W	Pathogenic	1.0
MEN1	O00255-1.4	P282A	Pathogenic	0.997
MEN1	O00255-1.4	P282C	Pathogenic	0.987
MEN1	O00255-1.4	P282D	Pathogenic	0.997
MEN1	O00255-1.4	P282E	Pathogenic	0.999
MEN1	O00255-1.4	P282F	Pathogenic	1.0
MEN1	O00255-1.4	P282G	Pathogenic	1.0
MEN1	O00255-1.4	P282H	Pathogenic	0.999
MEN1	O00255-1.4	P282I	Pathogenic	1.0
MEN1	O00255-1.4	P282K	Pathogenic	1.0
MEN1	O00255-1.4	P282L	Pathogenic	1.0
MEN1	O00255-1.4	P282M	Pathogenic	0.999
MEN1	O00255-1.4	P282N	Pathogenic	0.998
MEN1	O00255-1.4	P282Q	Pathogenic	0.999
MEN1	O00255-1.4	P282R	Pathogenic	1.0
MEN1	O00255-1.4	P282S	Pathogenic	0.997
MEN1	O00255-1.4	P282T	Pathogenic	0.989
MEN1	O00255-1.4	P282V	Pathogenic	0.996
MEN1	O00255-1.4	P282W	Pathogenic	1.0
MEN1	O00255-1.4	P282Y	Pathogenic	1.0
MEN1	O00255-1.4	M283A	Pathogenic	1.0
MEN1	O00255-1.4	M283C	Pathogenic	1.0
MEN1	O00255-1.4	M283D	Pathogenic	1.0
MEN1	O00255-1.4	M283E	Pathogenic	1.0
MEN1	O00255-1.4	M283F	Pathogenic	0.999
MEN1	O00255-1.4	M283G	Pathogenic	1.0
MEN1	O00255-1.4	M283H	Pathogenic	1.0
MEN1	O00255-1.4	M283I	Pathogenic	0.999
MEN1	O00255-1.4	M283K	Pathogenic	1.0
MEN1	O00255-1.4	M283L	Pathogenic	0.998
MEN1	O00255-1.4	M283N	Pathogenic	1.0
MEN1	O00255-1.4	M283P	Pathogenic	1.0
MEN1	O00255-1.4	M283Q	Pathogenic	1.0
MEN1	O00255-1.4	M283R	Pathogenic	1.0
MEN1	O00255-1.4	M283S	Pathogenic	1.0
MEN1	O00255-1.4	M283T	Pathogenic	1.0
MEN1	O00255-1.4	M283V	Pathogenic	0.999
MEN1	O00255-1.4	M283W	Pathogenic	1.0
MEN1	O00255-1.4	M283Y	Pathogenic	1.0
MEN1	O00255-1.4	A284C	Pathogenic	0.988
MEN1	O00255-1.4	A284D	Pathogenic	0.996
MEN1	O00255-1.4	A284E	Pathogenic	0.999
MEN1	O00255-1.4	A284F	Pathogenic	1.0
MEN1	O00255-1.4	A284G	Pathogenic	0.979
MEN1	O00255-1.4	A284H	Pathogenic	0.998
MEN1	O00255-1.4	A284I	Pathogenic	1.0
MEN1	O00255-1.4	A284K	Pathogenic	1.0
MEN1	O00255-1.4	A284L	Pathogenic	1.0
MEN1	O00255-1.4	A284M	Pathogenic	1.0
MEN1	O00255-1.4	A284N	Pathogenic	0.997
MEN1	O00255-1.4	A284P	Pathogenic	0.988
MEN1	O00255-1.4	A284Q	Pathogenic	0.998
MEN1	O00255-1.4	A284R	Pathogenic	1.0
MEN1	O00255-1.4	A284S	Pathogenic	0.947
MEN1	O00255-1.4	A284T	Pathogenic	0.981
MEN1	O00255-1.4	A284V	Pathogenic	0.998
MEN1	O00255-1.4	A284W	Pathogenic	1.0
MEN1	O00255-1.4	A284Y	Pathogenic	1.0
MEN1	O00255-1.4	L285A	Pathogenic	0.999
MEN1	O00255-1.4	L285C	Pathogenic	0.984
MEN1	O00255-1.4	L285D	Pathogenic	0.999
MEN1	O00255-1.4	L285E	Pathogenic	0.994
MEN1	O00255-1.4	L285F	Pathogenic	0.736
MEN1	O00255-1.4	L285G	Pathogenic	1.0
MEN1	O00255-1.4	L285H	Pathogenic	0.962
MEN1	O00255-1.4	L285I	Pathogenic	0.526
MEN1	O00255-1.4	L285K	Pathogenic	0.995
MEN1	O00255-1.4	L285M	Pathogenic	0.668
MEN1	O00255-1.4	L285N	Pathogenic	0.998
MEN1	O00255-1.4	L285P	Pathogenic	0.988
MEN1	O00255-1.4	L285Q	Pathogenic	0.983
MEN1	O00255-1.4	L285R	Pathogenic	0.998
MEN1	O00255-1.4	L285S	Pathogenic	0.999
MEN1	O00255-1.4	L285T	Pathogenic	0.992
MEN1	O00255-1.4	L285V	Pathogenic	0.9
MEN1	O00255-1.4	L285W	Pathogenic	0.982
MEN1	O00255-1.4	L285Y	Pathogenic	0.93
MEN1	O00255-1.4	G286A	Pathogenic	0.993
MEN1	O00255-1.4	G286C	Pathogenic	0.999
MEN1	O00255-1.4	G286D	Pathogenic	0.999
MEN1	O00255-1.4	G286E	Pathogenic	1.0
MEN1	O00255-1.4	G286F	Pathogenic	1.0
MEN1	O00255-1.4	G286H	Pathogenic	1.0
MEN1	O00255-1.4	G286I	Pathogenic	1.0
MEN1	O00255-1.4	G286K	Pathogenic	1.0
MEN1	O00255-1.4	G286L	Pathogenic	1.0
MEN1	O00255-1.4	G286M	Pathogenic	1.0
MEN1	O00255-1.4	G286N	Pathogenic	0.999
MEN1	O00255-1.4	G286P	Pathogenic	0.999
MEN1	O00255-1.4	G286Q	Pathogenic	1.0
MEN1	O00255-1.4	G286R	Pathogenic	1.0
MEN1	O00255-1.4	G286S	Pathogenic	0.993
MEN1	O00255-1.4	G286T	Pathogenic	0.999
MEN1	O00255-1.4	G286V	Pathogenic	1.0
MEN1	O00255-1.4	G286W	Pathogenic	1.0
MEN1	O00255-1.4	G286Y	Pathogenic	1.0
MEN1	O00255-1.4	N287A	Pathogenic	0.998
MEN1	O00255-1.4	N287C	Pathogenic	0.998
MEN1	O00255-1.4	N287D	Pathogenic	0.961
MEN1	O00255-1.4	N287E	Pathogenic	0.975
MEN1	O00255-1.4	N287F	Pathogenic	1.0
MEN1	O00255-1.4	N287G	Pathogenic	0.999
MEN1	O00255-1.4	N287H	Pathogenic	0.995
MEN1	O00255-1.4	N287I	Pathogenic	1.0
MEN1	O00255-1.4	N287K	Pathogenic	0.998
MEN1	O00255-1.4	N287L	Pathogenic	1.0
MEN1	O00255-1.4	N287M	Pathogenic	1.0
MEN1	O00255-1.4	N287P	Pathogenic	0.995
MEN1	O00255-1.4	N287Q	Pathogenic	0.99
MEN1	O00255-1.4	N287R	Pathogenic	0.999
MEN1	O00255-1.4	N287S	Pathogenic	0.995
MEN1	O00255-1.4	N287T	Pathogenic	0.986
MEN1	O00255-1.4	N287V	Pathogenic	0.998
MEN1	O00255-1.4	N287W	Pathogenic	1.0
MEN1	O00255-1.4	N287Y	Pathogenic	1.0
MEN1	O00255-1.4	L288A	Pathogenic	1.0
MEN1	O00255-1.4	L288C	Pathogenic	0.999
MEN1	O00255-1.4	L288D	Pathogenic	1.0
MEN1	O00255-1.4	L288E	Pathogenic	1.0
MEN1	O00255-1.4	L288F	Pathogenic	0.977
MEN1	O00255-1.4	L288G	Pathogenic	1.0
MEN1	O00255-1.4	L288H	Pathogenic	0.997
MEN1	O00255-1.4	L288I	Pathogenic	0.945
MEN1	O00255-1.4	L288K	Pathogenic	1.0
MEN1	O00255-1.4	L288M	Pathogenic	0.969
MEN1	O00255-1.4	L288N	Pathogenic	1.0
MEN1	O00255-1.4	L288P	Pathogenic	0.999
MEN1	O00255-1.4	L288Q	Pathogenic	0.999
MEN1	O00255-1.4	L288R	Pathogenic	1.0
MEN1	O00255-1.4	L288S	Pathogenic	1.0
MEN1	O00255-1.4	L288T	Pathogenic	0.999
MEN1	O00255-1.4	L288V	Pathogenic	0.993
MEN1	O00255-1.4	L288W	Pathogenic	0.999
MEN1	O00255-1.4	L288Y	Pathogenic	0.995
MEN1	O00255-1.4	A289C	Pathogenic	0.94
MEN1	O00255-1.4	A289D	Pathogenic	0.98
MEN1	O00255-1.4	A289E	Pathogenic	0.993
MEN1	O00255-1.4	A289F	Pathogenic	1.0
MEN1	O00255-1.4	A289G	Pathogenic	0.897
MEN1	O00255-1.4	A289H	Pathogenic	0.989
MEN1	O00255-1.4	A289I	Pathogenic	0.999
MEN1	O00255-1.4	A289K	Pathogenic	0.999
MEN1	O00255-1.4	A289L	Pathogenic	0.999
MEN1	O00255-1.4	A289M	Pathogenic	0.998
MEN1	O00255-1.4	A289N	Pathogenic	0.982
MEN1	O00255-1.4	A289P	Pathogenic	0.936
MEN1	O00255-1.4	A289Q	Pathogenic	0.991
MEN1	O00255-1.4	A289R	Pathogenic	1.0
MEN1	O00255-1.4	A289S	Pathogenic	0.767
MEN1	O00255-1.4	A289T	Pathogenic	0.906
MEN1	O00255-1.4	A289V	Pathogenic	0.99
MEN1	O00255-1.4	A289W	Pathogenic	1.0
MEN1	O00255-1.4	A289Y	Pathogenic	0.999
MEN1	O00255-1.4	D290A	Pathogenic	0.998
MEN1	O00255-1.4	D290C	Pathogenic	0.998
MEN1	O00255-1.4	D290E	Pathogenic	0.983
MEN1	O00255-1.4	D290F	Pathogenic	1.0
MEN1	O00255-1.4	D290G	Pathogenic	0.999
MEN1	O00255-1.4	D290H	Pathogenic	0.998
MEN1	O00255-1.4	D290I	Pathogenic	1.0
MEN1	O00255-1.4	D290K	Pathogenic	0.998
MEN1	O00255-1.4	D290L	Pathogenic	1.0
MEN1	O00255-1.4	D290M	Pathogenic	1.0
MEN1	O00255-1.4	D290N	Pathogenic	0.96
MEN1	O00255-1.4	D290P	Pathogenic	0.994
MEN1	O00255-1.4	D290Q	Pathogenic	0.995
MEN1	O00255-1.4	D290R	Pathogenic	0.999
MEN1	O00255-1.4	D290S	Pathogenic	0.994
MEN1	O00255-1.4	D290T	Pathogenic	0.989
MEN1	O00255-1.4	D290V	Pathogenic	0.999
MEN1	O00255-1.4	D290W	Pathogenic	1.0
MEN1	O00255-1.4	D290Y	Pathogenic	1.0
MEN1	O00255-1.4	L291A	Pathogenic	1.0
MEN1	O00255-1.4	L291C	Pathogenic	0.999
MEN1	O00255-1.4	L291D	Pathogenic	1.0
MEN1	O00255-1.4	L291E	Pathogenic	1.0
MEN1	O00255-1.4	L291F	Pathogenic	0.977
MEN1	O00255-1.4	L291G	Pathogenic	1.0
MEN1	O00255-1.4	L291H	Pathogenic	0.997
MEN1	O00255-1.4	L291I	Pathogenic	0.945
MEN1	O00255-1.4	L291K	Pathogenic	1.0
MEN1	O00255-1.4	L291M	Pathogenic	0.969
MEN1	O00255-1.4	L291N	Pathogenic	1.0
MEN1	O00255-1.4	L291P	Pathogenic	0.999
MEN1	O00255-1.4	L291Q	Pathogenic	0.999
MEN1	O00255-1.4	L291R	Pathogenic	1.0
MEN1	O00255-1.4	L291S	Pathogenic	1.0
MEN1	O00255-1.4	L291T	Pathogenic	0.999
MEN1	O00255-1.4	L291V	Pathogenic	0.993
MEN1	O00255-1.4	L291W	Pathogenic	0.999
MEN1	O00255-1.4	L291Y	Pathogenic	0.995
MEN1	O00255-1.4	E292A	Pathogenic	1.0
MEN1	O00255-1.4	E292C	Pathogenic	1.0
MEN1	O00255-1.4	E292D	Pathogenic	0.989
MEN1	O00255-1.4	E292F	Pathogenic	1.0
MEN1	O00255-1.4	E292G	Pathogenic	1.0
MEN1	O00255-1.4	E292H	Pathogenic	0.993
MEN1	O00255-1.4	E292I	Pathogenic	1.0
MEN1	O00255-1.4	E292K	Pathogenic	0.996
MEN1	O00255-1.4	E292L	Pathogenic	1.0
MEN1	O00255-1.4	E292M	Pathogenic	0.999
MEN1	O00255-1.4	E292N	Pathogenic	0.983
MEN1	O00255-1.4	E292P	Pathogenic	0.999
MEN1	O00255-1.4	E292Q	Pathogenic	0.982
MEN1	O00255-1.4	E292R	Pathogenic	0.999
MEN1	O00255-1.4	E292S	Pathogenic	0.999
MEN1	O00255-1.4	E292T	Pathogenic	0.997
MEN1	O00255-1.4	E292V	Pathogenic	0.998
MEN1	O00255-1.4	E292W	Pathogenic	1.0
MEN1	O00255-1.4	E292Y	Pathogenic	1.0
MEN1	O00255-1.4	E293A	Pathogenic	0.993
MEN1	O00255-1.4	E293C	Pathogenic	0.992
MEN1	O00255-1.4	E293D	Pathogenic	0.834
MEN1	O00255-1.4	E293F	Pathogenic	0.998
MEN1	O00255-1.4	E293G	Pathogenic	0.997
MEN1	O00255-1.4	E293H	Pathogenic	0.891
MEN1	O00255-1.4	E293I	Pathogenic	0.996
MEN1	O00255-1.4	E293K	Pathogenic	0.933
MEN1	O00255-1.4	E293L	Pathogenic	0.995
MEN1	O00255-1.4	E293M	Pathogenic	0.988
MEN1	O00255-1.4	E293N	Pathogenic	0.77
MEN1	O00255-1.4	E293P	Pathogenic	0.979
MEN1	O00255-1.4	E293Q	Pathogenic	0.752
MEN1	O00255-1.4	E293R	Pathogenic	0.976
MEN1	O00255-1.4	E293S	Pathogenic	0.979
MEN1	O00255-1.4	E293T	Pathogenic	0.947
MEN1	O00255-1.4	E293V	Pathogenic	0.974
MEN1	O00255-1.4	E293W	Pathogenic	1.0
MEN1	O00255-1.4	E293Y	Pathogenic	0.995
MEN1	O00255-1.4	L294A	Pathogenic	0.964
MEN1	O00255-1.4	L294C	Pathogenic	0.682
MEN1	O00255-1.4	L294D	Pathogenic	0.968
MEN1	O00255-1.4	L294E	Pathogenic	0.857
MEN1	O00255-1.4	L294F	Neutral	0.088
MEN1	O00255-1.4	L294G	Pathogenic	0.995
MEN1	O00255-1.4	L294H	Neutral	0.468
MEN1	O00255-1.4	L294I	Neutral	0.037
MEN1	O00255-1.4	L294K	Pathogenic	0.881
MEN1	O00255-1.4	L294M	Neutral	0.065
MEN1	O00255-1.4	L294N	Pathogenic	0.937
MEN1	O00255-1.4	L294P	Pathogenic	0.733
MEN1	O00255-1.4	L294Q	Pathogenic	0.664
MEN1	O00255-1.4	L294R	Pathogenic	0.953
MEN1	O00255-1.4	L294S	Pathogenic	0.969
MEN1	O00255-1.4	L294T	Pathogenic	0.805
MEN1	O00255-1.4	L294V	Neutral	0.239
MEN1	O00255-1.4	L294W	Pathogenic	0.651
MEN1	O00255-1.4	L294Y	Neutral	0.316
MEN1	O00255-1.4	E295A	Pathogenic	0.884
MEN1	O00255-1.4	E295C	Pathogenic	0.869
MEN1	O00255-1.4	E295D	Neutral	0.221
MEN1	O00255-1.4	E295F	Pathogenic	0.966
MEN1	O00255-1.4	E295G	Pathogenic	0.953
MEN1	O00255-1.4	E295H	Neutral	0.315
MEN1	O00255-1.4	E295I	Pathogenic	0.928
MEN1	O00255-1.4	E295K	Neutral	0.439
MEN1	O00255-1.4	E295L	Pathogenic	0.917
MEN1	O00255-1.4	E295M	Pathogenic	0.829
MEN1	O00255-1.4	E295N	Neutral	0.159
MEN1	O00255-1.4	E295P	Pathogenic	0.727
MEN1	O00255-1.4	E295Q	Neutral	0.146
MEN1	O00255-1.4	E295R	Pathogenic	0.692
MEN1	O00255-1.4	E295S	Pathogenic	0.724
MEN1	O00255-1.4	E295T	Pathogenic	0.502
MEN1	O00255-1.4	E295V	Pathogenic	0.675
MEN1	O00255-1.4	E295W	Pathogenic	0.998
MEN1	O00255-1.4	E295Y	Pathogenic	0.917
MEN1	O00255-1.4	P296A	Pathogenic	0.985
MEN1	O00255-1.4	P296C	Pathogenic	0.933
MEN1	O00255-1.4	P296D	Pathogenic	0.986
MEN1	O00255-1.4	P296E	Pathogenic	0.995
MEN1	O00255-1.4	P296F	Pathogenic	0.999
MEN1	O00255-1.4	P296G	Pathogenic	0.998
MEN1	O00255-1.4	P296H	Pathogenic	0.992
MEN1	O00255-1.4	P296I	Pathogenic	0.998
MEN1	O00255-1.4	P296K	Pathogenic	1.0
MEN1	O00255-1.4	P296L	Pathogenic	0.998
MEN1	O00255-1.4	P296M	Pathogenic	0.995
MEN1	O00255-1.4	P296N	Pathogenic	0.988
MEN1	O00255-1.4	P296Q	Pathogenic	0.994
MEN1	O00255-1.4	P296R	Pathogenic	1.0
MEN1	O00255-1.4	P296S	Pathogenic	0.986
MEN1	O00255-1.4	P296T	Pathogenic	0.94
MEN1	O00255-1.4	P296V	Pathogenic	0.977
MEN1	O00255-1.4	P296W	Pathogenic	1.0
MEN1	O00255-1.4	P296Y	Pathogenic	0.998
MEN1	O00255-1.4	T297A	Pathogenic	0.947
MEN1	O00255-1.4	T297C	Pathogenic	0.932
MEN1	O00255-1.4	T297D	Pathogenic	0.939
MEN1	O00255-1.4	T297E	Pathogenic	0.973
MEN1	O00255-1.4	T297F	Pathogenic	0.999
MEN1	O00255-1.4	T297G	Pathogenic	0.992
MEN1	O00255-1.4	T297H	Pathogenic	0.955
MEN1	O00255-1.4	T297I	Pathogenic	0.997
MEN1	O00255-1.4	T297K	Pathogenic	0.998
MEN1	O00255-1.4	T297L	Pathogenic	0.996
MEN1	O00255-1.4	T297M	Pathogenic	0.992
MEN1	O00255-1.4	T297N	Pathogenic	0.923
MEN1	O00255-1.4	T297P	Pathogenic	0.87
MEN1	O00255-1.4	T297Q	Pathogenic	0.963
MEN1	O00255-1.4	T297R	Pathogenic	0.999
MEN1	O00255-1.4	T297S	Pathogenic	0.941
MEN1	O00255-1.4	T297V	Pathogenic	0.965
MEN1	O00255-1.4	T297W	Pathogenic	1.0
MEN1	O00255-1.4	T297Y	Pathogenic	0.997
MEN1	O00255-1.4	P298A	Pathogenic	0.875
MEN1	O00255-1.4	P298C	Pathogenic	0.601
MEN1	O00255-1.4	P298D	Pathogenic	0.886
MEN1	O00255-1.4	P298E	Pathogenic	0.96
MEN1	O00255-1.4	P298F	Pathogenic	0.992
MEN1	O00255-1.4	P298G	Pathogenic	0.981
MEN1	O00255-1.4	P298H	Pathogenic	0.935
MEN1	O00255-1.4	P298I	Pathogenic	0.982
MEN1	O00255-1.4	P298K	Pathogenic	0.997
MEN1	O00255-1.4	P298L	Pathogenic	0.978
MEN1	O00255-1.4	P298M	Pathogenic	0.952
MEN1	O00255-1.4	P298N	Pathogenic	0.901
MEN1	O00255-1.4	P298Q	Pathogenic	0.947
MEN1	O00255-1.4	P298R	Pathogenic	0.999
MEN1	O00255-1.4	P298S	Pathogenic	0.887
MEN1	O00255-1.4	P298T	Pathogenic	0.631
MEN1	O00255-1.4	P298V	Pathogenic	0.825
MEN1	O00255-1.4	P298W	Pathogenic	1.0
MEN1	O00255-1.4	P298Y	Pathogenic	0.98
MEN1	O00255-1.4	G299A	Pathogenic	0.96
MEN1	O00255-1.4	G299C	Pathogenic	0.997
MEN1	O00255-1.4	G299D	Pathogenic	0.997
MEN1	O00255-1.4	G299E	Pathogenic	0.999
MEN1	O00255-1.4	G299F	Pathogenic	1.0
MEN1	O00255-1.4	G299H	Pathogenic	0.999
MEN1	O00255-1.4	G299I	Pathogenic	1.0
MEN1	O00255-1.4	G299K	Pathogenic	1.0
MEN1	O00255-1.4	G299L	Pathogenic	1.0
MEN1	O00255-1.4	G299M	Pathogenic	1.0
MEN1	O00255-1.4	G299N	Pathogenic	0.997
MEN1	O00255-1.4	G299P	Pathogenic	0.997
MEN1	O00255-1.4	G299Q	Pathogenic	0.999
MEN1	O00255-1.4	G299R	Pathogenic	1.0
MEN1	O00255-1.4	G299S	Pathogenic	0.96
MEN1	O00255-1.4	G299T	Pathogenic	0.994
MEN1	O00255-1.4	G299V	Pathogenic	1.0
MEN1	O00255-1.4	G299W	Pathogenic	1.0
MEN1	O00255-1.4	G299Y	Pathogenic	1.0
MEN1	O00255-1.4	R300A	Pathogenic	1.0
MEN1	O00255-1.4	R300C	Pathogenic	1.0
MEN1	O00255-1.4	R300D	Pathogenic	0.998
MEN1	O00255-1.4	R300E	Pathogenic	0.991
MEN1	O00255-1.4	R300F	Pathogenic	0.999
MEN1	O00255-1.4	R300G	Pathogenic	1.0
MEN1	O00255-1.4	R300H	Pathogenic	0.995
MEN1	O00255-1.4	R300I	Pathogenic	1.0
MEN1	O00255-1.4	R300K	Pathogenic	0.893
MEN1	O00255-1.4	R300L	Pathogenic	0.999
MEN1	O00255-1.4	R300M	Pathogenic	0.999
MEN1	O00255-1.4	R300N	Pathogenic	0.997
MEN1	O00255-1.4	R300P	Pathogenic	1.0
MEN1	O00255-1.4	R300Q	Pathogenic	0.993
MEN1	O00255-1.4	R300S	Pathogenic	1.0
MEN1	O00255-1.4	R300T	Pathogenic	0.999
MEN1	O00255-1.4	R300V	Pathogenic	1.0
MEN1	O00255-1.4	R300W	Pathogenic	1.0
MEN1	O00255-1.4	R300Y	Pathogenic	0.994
MEN1	O00255-1.4	P301A	Pathogenic	0.801
MEN1	O00255-1.4	P301C	Neutral	0.464
MEN1	O00255-1.4	P301D	Pathogenic	0.817
MEN1	O00255-1.4	P301E	Pathogenic	0.933
MEN1	O00255-1.4	P301F	Pathogenic	0.986
MEN1	O00255-1.4	P301G	Pathogenic	0.967
MEN1	O00255-1.4	P301H	Pathogenic	0.892
MEN1	O00255-1.4	P301I	Pathogenic	0.969
MEN1	O00255-1.4	P301K	Pathogenic	0.994
MEN1	O00255-1.4	P301L	Pathogenic	0.963
MEN1	O00255-1.4	P301M	Pathogenic	0.92
MEN1	O00255-1.4	P301N	Pathogenic	0.84
MEN1	O00255-1.4	P301Q	Pathogenic	0.911
MEN1	O00255-1.4	P301R	Pathogenic	0.998
MEN1	O00255-1.4	P301S	Pathogenic	0.818
MEN1	O00255-1.4	P301T	Neutral	0.495
MEN1	O00255-1.4	P301V	Pathogenic	0.731
MEN1	O00255-1.4	P301W	Pathogenic	0.999
MEN1	O00255-1.4	P301Y	Pathogenic	0.965
MEN1	O00255-1.4	D302A	Pathogenic	0.804
MEN1	O00255-1.4	D302C	Pathogenic	0.759
MEN1	O00255-1.4	D302E	Neutral	0.308
MEN1	O00255-1.4	D302F	Pathogenic	0.995
MEN1	O00255-1.4	D302G	Pathogenic	0.906
MEN1	O00255-1.4	D302H	Pathogenic	0.784
MEN1	O00255-1.4	D302I	Pathogenic	0.99
MEN1	O00255-1.4	D302K	Pathogenic	0.811
MEN1	O00255-1.4	D302L	Pathogenic	0.989
MEN1	O00255-1.4	D302M	Pathogenic	0.974
MEN1	O00255-1.4	D302N	Neutral	0.159
MEN1	O00255-1.4	D302P	Pathogenic	0.574
MEN1	O00255-1.4	D302Q	Pathogenic	0.589
MEN1	O00255-1.4	D302R	Pathogenic	0.925
MEN1	O00255-1.4	D302S	Pathogenic	0.57
MEN1	O00255-1.4	D302T	Neutral	0.407
MEN1	O00255-1.4	D302V	Pathogenic	0.9
MEN1	O00255-1.4	D302W	Pathogenic	1.0
MEN1	O00255-1.4	D302Y	Pathogenic	0.989
MEN1	O00255-1.4	P303A	Pathogenic	0.894
MEN1	O00255-1.4	P303C	Pathogenic	0.645
MEN1	O00255-1.4	P303D	Pathogenic	0.904
MEN1	O00255-1.4	P303E	Pathogenic	0.967
MEN1	O00255-1.4	P303F	Pathogenic	0.993
MEN1	O00255-1.4	P303G	Pathogenic	0.984
MEN1	O00255-1.4	P303H	Pathogenic	0.945
MEN1	O00255-1.4	P303I	Pathogenic	0.985
MEN1	O00255-1.4	P303K	Pathogenic	0.997
MEN1	O00255-1.4	P303L	Pathogenic	0.982
MEN1	O00255-1.4	P303M	Pathogenic	0.96
MEN1	O00255-1.4	P303N	Pathogenic	0.917
MEN1	O00255-1.4	P303Q	Pathogenic	0.955
MEN1	O00255-1.4	P303R	Pathogenic	0.999
MEN1	O00255-1.4	P303S	Pathogenic	0.904
MEN1	O00255-1.4	P303T	Pathogenic	0.673
MEN1	O00255-1.4	P303V	Pathogenic	0.851
MEN1	O00255-1.4	P303W	Pathogenic	1.0
MEN1	O00255-1.4	P303Y	Pathogenic	0.983
MEN1	O00255-1.4	L304A	Pathogenic	0.974
MEN1	O00255-1.4	L304C	Pathogenic	0.753
MEN1	O00255-1.4	L304D	Pathogenic	0.977
MEN1	O00255-1.4	L304E	Pathogenic	0.895
MEN1	O00255-1.4	L304F	Neutral	0.121
MEN1	O00255-1.4	L304G	Pathogenic	0.997
MEN1	O00255-1.4	L304H	Pathogenic	0.556
MEN1	O00255-1.4	L304I	Neutral	0.052
MEN1	O00255-1.4	L304K	Pathogenic	0.914
MEN1	O00255-1.4	L304M	Neutral	0.091
MEN1	O00255-1.4	L304N	Pathogenic	0.955
MEN1	O00255-1.4	L304P	Pathogenic	0.797
MEN1	O00255-1.4	L304Q	Pathogenic	0.738
MEN1	O00255-1.4	L304R	Pathogenic	0.966
MEN1	O00255-1.4	L304S	Pathogenic	0.978
MEN1	O00255-1.4	L304T	Pathogenic	0.855
MEN1	O00255-1.4	L304V	Neutral	0.309
MEN1	O00255-1.4	L304W	Pathogenic	0.727
MEN1	O00255-1.4	L304Y	Neutral	0.397
MEN1	O00255-1.4	T305A	Neutral	0.127
MEN1	O00255-1.4	T305C	Neutral	0.101
MEN1	O00255-1.4	T305D	Neutral	0.111
MEN1	O00255-1.4	T305E	Neutral	0.223
MEN1	O00255-1.4	T305F	Pathogenic	0.857
MEN1	O00255-1.4	T305G	Neutral	0.487
MEN1	O00255-1.4	T305H	Neutral	0.147
MEN1	O00255-1.4	T305I	Pathogenic	0.718
MEN1	O00255-1.4	T305K	Pathogenic	0.78
MEN1	O00255-1.4	T305L	Pathogenic	0.683
MEN1	O00255-1.4	T305M	Pathogenic	0.501
MEN1	O00255-1.4	T305N	Neutral	0.088
MEN1	O00255-1.4	T305P	Neutral	0.051
MEN1	O00255-1.4	T305Q	Neutral	0.175
MEN1	O00255-1.4	T305R	Pathogenic	0.906
MEN1	O00255-1.4	T305S	Neutral	0.115
MEN1	O00255-1.4	T305V	Neutral	0.183
MEN1	O00255-1.4	T305W	Pathogenic	0.99
MEN1	O00255-1.4	T305Y	Pathogenic	0.71
MEN1	O00255-1.4	L306A	Pathogenic	0.998
MEN1	O00255-1.4	L306C	Pathogenic	0.981
MEN1	O00255-1.4	L306D	Pathogenic	0.999
MEN1	O00255-1.4	L306E	Pathogenic	0.993
MEN1	O00255-1.4	L306F	Pathogenic	0.703
MEN1	O00255-1.4	L306G	Pathogenic	1.0
MEN1	O00255-1.4	L306H	Pathogenic	0.956
MEN1	O00255-1.4	L306I	Neutral	0.486
MEN1	O00255-1.4	L306K	Pathogenic	0.995
MEN1	O00255-1.4	L306M	Pathogenic	0.632
MEN1	O00255-1.4	L306N	Pathogenic	0.997
MEN1	O00255-1.4	L306P	Pathogenic	0.985
MEN1	O00255-1.4	L306Q	Pathogenic	0.98
MEN1	O00255-1.4	L306R	Pathogenic	0.998
MEN1	O00255-1.4	L306S	Pathogenic	0.999
MEN1	O00255-1.4	L306T	Pathogenic	0.99
MEN1	O00255-1.4	L306V	Pathogenic	0.885
MEN1	O00255-1.4	L306W	Pathogenic	0.979
MEN1	O00255-1.4	L306Y	Pathogenic	0.919
MEN1	O00255-1.4	Y307A	Pathogenic	0.999
MEN1	O00255-1.4	Y307C	Pathogenic	0.989
MEN1	O00255-1.4	Y307D	Pathogenic	0.999
MEN1	O00255-1.4	Y307E	Pathogenic	0.995
MEN1	O00255-1.4	Y307F	Pathogenic	0.868
MEN1	O00255-1.4	Y307G	Pathogenic	1.0
MEN1	O00255-1.4	Y307H	Pathogenic	0.961
MEN1	O00255-1.4	Y307I	Pathogenic	0.951
MEN1	O00255-1.4	Y307K	Pathogenic	0.982
MEN1	O00255-1.4	Y307L	Pathogenic	0.943
MEN1	O00255-1.4	Y307M	Pathogenic	0.885
MEN1	O00255-1.4	Y307N	Pathogenic	0.998
MEN1	O00255-1.4	Y307P	Pathogenic	0.991
MEN1	O00255-1.4	Y307Q	Pathogenic	0.986
MEN1	O00255-1.4	Y307R	Pathogenic	0.984
MEN1	O00255-1.4	Y307S	Pathogenic	0.999
MEN1	O00255-1.4	Y307T	Pathogenic	0.994
MEN1	O00255-1.4	Y307V	Pathogenic	0.969
MEN1	O00255-1.4	Y307W	Pathogenic	0.98
MEN1	O00255-1.4	H308A	Pathogenic	0.96
MEN1	O00255-1.4	H308C	Pathogenic	0.948
MEN1	O00255-1.4	H308D	Pathogenic	0.924
MEN1	O00255-1.4	H308E	Pathogenic	0.706
MEN1	O00255-1.4	H308F	Pathogenic	0.951
MEN1	O00255-1.4	H308G	Pathogenic	0.989
MEN1	O00255-1.4	H308I	Pathogenic	0.909
MEN1	O00255-1.4	H308K	Pathogenic	0.892
MEN1	O00255-1.4	H308L	Pathogenic	0.894
MEN1	O00255-1.4	H308M	Pathogenic	0.787
MEN1	O00255-1.4	H308N	Pathogenic	0.849
MEN1	O00255-1.4	H308P	Pathogenic	0.893
MEN1	O00255-1.4	H308Q	Neutral	0.457
MEN1	O00255-1.4	H308R	Pathogenic	0.954
MEN1	O00255-1.4	H308S	Pathogenic	0.934
MEN1	O00255-1.4	H308T	Pathogenic	0.759
MEN1	O00255-1.4	H308V	Pathogenic	0.866
MEN1	O00255-1.4	H308W	Pathogenic	0.997
MEN1	O00255-1.4	H308Y	Pathogenic	0.87
MEN1	O00255-1.4	K309A	Pathogenic	0.999
MEN1	O00255-1.4	K309C	Pathogenic	0.999
MEN1	O00255-1.4	K309D	Pathogenic	0.981
MEN1	O00255-1.4	K309E	Pathogenic	0.937
MEN1	O00255-1.4	K309F	Pathogenic	0.993
MEN1	O00255-1.4	K309G	Pathogenic	1.0
MEN1	O00255-1.4	K309H	Pathogenic	0.968
MEN1	O00255-1.4	K309I	Pathogenic	0.997
MEN1	O00255-1.4	K309L	Pathogenic	0.996
MEN1	O00255-1.4	K309M	Pathogenic	0.991
MEN1	O00255-1.4	K309N	Pathogenic	0.978
MEN1	O00255-1.4	K309P	Pathogenic	0.998
MEN1	O00255-1.4	K309Q	Pathogenic	0.953
MEN1	O00255-1.4	K309R	Pathogenic	0.754
MEN1	O00255-1.4	K309S	Pathogenic	0.998
MEN1	O00255-1.4	K309T	Pathogenic	0.996
MEN1	O00255-1.4	K309V	Pathogenic	0.998
MEN1	O00255-1.4	K309W	Pathogenic	1.0
MEN1	O00255-1.4	K309Y	Pathogenic	0.982
MEN1	O00255-1.4	G310A	Pathogenic	0.575
MEN1	O00255-1.4	G310C	Pathogenic	0.952
MEN1	O00255-1.4	G310D	Pathogenic	0.948
MEN1	O00255-1.4	G310E	Pathogenic	0.984
MEN1	O00255-1.4	G310F	Pathogenic	1.0
MEN1	O00255-1.4	G310H	Pathogenic	0.981
MEN1	O00255-1.4	G310I	Pathogenic	0.999
MEN1	O00255-1.4	G310K	Pathogenic	0.999
MEN1	O00255-1.4	G310L	Pathogenic	0.999
MEN1	O00255-1.4	G310M	Pathogenic	0.998
MEN1	O00255-1.4	G310N	Pathogenic	0.95
MEN1	O00255-1.4	G310P	Pathogenic	0.943
MEN1	O00255-1.4	G310Q	Pathogenic	0.978
MEN1	O00255-1.4	G310R	Pathogenic	1.0
MEN1	O00255-1.4	G310S	Pathogenic	0.577
MEN1	O00255-1.4	G310T	Pathogenic	0.907
MEN1	O00255-1.4	G310V	Pathogenic	0.992
MEN1	O00255-1.4	G310W	Pathogenic	1.0
MEN1	O00255-1.4	G310Y	Pathogenic	0.999
MEN1	O00255-1.4	I311A	Pathogenic	1.0
MEN1	O00255-1.4	I311C	Pathogenic	0.995
MEN1	O00255-1.4	I311D	Pathogenic	1.0
MEN1	O00255-1.4	I311E	Pathogenic	0.998
MEN1	O00255-1.4	I311F	Pathogenic	0.866
MEN1	O00255-1.4	I311G	Pathogenic	1.0
MEN1	O00255-1.4	I311H	Pathogenic	0.987
MEN1	O00255-1.4	I311K	Pathogenic	0.999
MEN1	O00255-1.4	I311L	Pathogenic	0.743
MEN1	O00255-1.4	I311M	Pathogenic	0.868
MEN1	O00255-1.4	I311N	Pathogenic	0.999
MEN1	O00255-1.4	I311P	Pathogenic	0.996
MEN1	O00255-1.4	I311Q	Pathogenic	0.995
MEN1	O00255-1.4	I311R	Pathogenic	0.999
MEN1	O00255-1.4	I311S	Pathogenic	1.0
MEN1	O00255-1.4	I311T	Pathogenic	0.997
MEN1	O00255-1.4	I311V	Pathogenic	0.961
MEN1	O00255-1.4	I311W	Pathogenic	0.992
MEN1	O00255-1.4	I311Y	Pathogenic	0.976
MEN1	O00255-1.4	A312C	Neutral	0.013
MEN1	O00255-1.4	A312D	Neutral	0.04
MEN1	O00255-1.4	A312E	Neutral	0.108
MEN1	O00255-1.4	A312F	Pathogenic	0.68
MEN1	O00255-1.4	A312G	Neutral	0.007
MEN1	O00255-1.4	A312H	Neutral	0.067
MEN1	O00255-1.4	A312I	Neutral	0.474
MEN1	O00255-1.4	A312K	Pathogenic	0.598
MEN1	O00255-1.4	A312L	Neutral	0.433
MEN1	O00255-1.4	A312M	Neutral	0.263
MEN1	O00255-1.4	A312N	Neutral	0.044
MEN1	O00255-1.4	A312P	Neutral	0.012
MEN1	O00255-1.4	A312Q	Neutral	0.082
MEN1	O00255-1.4	A312R	Pathogenic	0.801
MEN1	O00255-1.4	A312S	Neutral	0.003
MEN1	O00255-1.4	A312T	Neutral	0.008
MEN1	O00255-1.4	A312V	Neutral	0.074
MEN1	O00255-1.4	A312W	Pathogenic	0.975
MEN1	O00255-1.4	A312Y	Neutral	0.465
MEN1	O00255-1.4	S313A	Pathogenic	0.869
MEN1	O00255-1.4	S313C	Pathogenic	0.974
MEN1	O00255-1.4	S313D	Pathogenic	0.97
MEN1	O00255-1.4	S313E	Pathogenic	0.99
MEN1	O00255-1.4	S313F	Pathogenic	1.0
MEN1	O00255-1.4	S313G	Pathogenic	0.947
MEN1	O00255-1.4	S313H	Pathogenic	0.99
MEN1	O00255-1.4	S313I	Pathogenic	1.0
MEN1	O00255-1.4	S313K	Pathogenic	0.999
MEN1	O00255-1.4	S313L	Pathogenic	1.0
MEN1	O00255-1.4	S313M	Pathogenic	0.999
MEN1	O00255-1.4	S313N	Pathogenic	0.971
MEN1	O00255-1.4	S313P	Pathogenic	0.971
MEN1	O00255-1.4	S313Q	Pathogenic	0.987
MEN1	O00255-1.4	S313R	Pathogenic	1.0
MEN1	O00255-1.4	S313T	Pathogenic	0.946
MEN1	O00255-1.4	S313V	Pathogenic	0.996
MEN1	O00255-1.4	S313W	Pathogenic	1.0
MEN1	O00255-1.4	S313Y	Pathogenic	1.0
MEN1	O00255-1.4	A314C	Pathogenic	0.946
MEN1	O00255-1.4	A314D	Pathogenic	0.982
MEN1	O00255-1.4	A314E	Pathogenic	0.994
MEN1	O00255-1.4	A314F	Pathogenic	1.0
MEN1	O00255-1.4	A314G	Pathogenic	0.907
MEN1	O00255-1.4	A314H	Pathogenic	0.99
MEN1	O00255-1.4	A314I	Pathogenic	0.999
MEN1	O00255-1.4	A314K	Pathogenic	0.999
MEN1	O00255-1.4	A314L	Pathogenic	0.999
MEN1	O00255-1.4	A314M	Pathogenic	0.998
MEN1	O00255-1.4	A314N	Pathogenic	0.984
MEN1	O00255-1.4	A314P	Pathogenic	0.943
MEN1	O00255-1.4	A314Q	Pathogenic	0.992
MEN1	O00255-1.4	A314R	Pathogenic	1.0
MEN1	O00255-1.4	A314S	Pathogenic	0.786
MEN1	O00255-1.4	A314T	Pathogenic	0.915
MEN1	O00255-1.4	A314V	Pathogenic	0.991
MEN1	O00255-1.4	A314W	Pathogenic	1.0
MEN1	O00255-1.4	A314Y	Pathogenic	0.999
MEN1	O00255-1.4	K315A	Pathogenic	0.997
MEN1	O00255-1.4	K315C	Pathogenic	0.997
MEN1	O00255-1.4	K315D	Pathogenic	0.918
MEN1	O00255-1.4	K315E	Pathogenic	0.762
MEN1	O00255-1.4	K315F	Pathogenic	0.968
MEN1	O00255-1.4	K315G	Pathogenic	0.999
MEN1	O00255-1.4	K315H	Pathogenic	0.865
MEN1	O00255-1.4	K315I	Pathogenic	0.986
MEN1	O00255-1.4	K315L	Pathogenic	0.982
MEN1	O00255-1.4	K315M	Pathogenic	0.961
MEN1	O00255-1.4	K315N	Pathogenic	0.905
MEN1	O00255-1.4	K315P	Pathogenic	0.993
MEN1	O00255-1.4	K315Q	Pathogenic	0.813
MEN1	O00255-1.4	K315R	Neutral	0.398
MEN1	O00255-1.4	K315S	Pathogenic	0.993
MEN1	O00255-1.4	K315T	Pathogenic	0.981
MEN1	O00255-1.4	K315V	Pathogenic	0.991
MEN1	O00255-1.4	K315W	Pathogenic	0.998
MEN1	O00255-1.4	K315Y	Pathogenic	0.92
MEN1	O00255-1.4	T316A	Neutral	0.18
MEN1	O00255-1.4	T316C	Neutral	0.144
MEN1	O00255-1.4	T316D	Neutral	0.158
MEN1	O00255-1.4	T316E	Neutral	0.302
MEN1	O00255-1.4	T316F	Pathogenic	0.9
MEN1	O00255-1.4	T316G	Pathogenic	0.588
MEN1	O00255-1.4	T316H	Neutral	0.205
MEN1	O00255-1.4	T316I	Pathogenic	0.793
MEN1	O00255-1.4	T316K	Pathogenic	0.842
MEN1	O00255-1.4	T316L	Pathogenic	0.764
MEN1	O00255-1.4	T316M	Pathogenic	0.602
MEN1	O00255-1.4	T316N	Neutral	0.127
MEN1	O00255-1.4	T316P	Neutral	0.075
MEN1	O00255-1.4	T316Q	Neutral	0.242
MEN1	O00255-1.4	T316R	Pathogenic	0.935
MEN1	O00255-1.4	T316S	Neutral	0.163
MEN1	O00255-1.4	T316V	Neutral	0.252
MEN1	O00255-1.4	T316W	Pathogenic	0.994
MEN1	O00255-1.4	T316Y	Pathogenic	0.786
MEN1	O00255-1.4	Y317A	Pathogenic	0.999
MEN1	O00255-1.4	Y317C	Pathogenic	0.992
MEN1	O00255-1.4	Y317D	Pathogenic	0.999
MEN1	O00255-1.4	Y317E	Pathogenic	0.996
MEN1	O00255-1.4	Y317F	Pathogenic	0.892
MEN1	O00255-1.4	Y317G	Pathogenic	1.0
MEN1	O00255-1.4	Y317H	Pathogenic	0.969
MEN1	O00255-1.4	Y317I	Pathogenic	0.961
MEN1	O00255-1.4	Y317K	Pathogenic	0.986
MEN1	O00255-1.4	Y317L	Pathogenic	0.954
MEN1	O00255-1.4	Y317M	Pathogenic	0.906
MEN1	O00255-1.4	Y317N	Pathogenic	0.999
MEN1	O00255-1.4	Y317P	Pathogenic	0.992
MEN1	O00255-1.4	Y317Q	Pathogenic	0.989
MEN1	O00255-1.4	Y317R	Pathogenic	0.987
MEN1	O00255-1.4	Y317S	Pathogenic	0.999
MEN1	O00255-1.4	Y317T	Pathogenic	0.995
MEN1	O00255-1.4	Y317V	Pathogenic	0.975
MEN1	O00255-1.4	Y317W	Pathogenic	0.984
MEN1	O00255-1.4	Y318A	Pathogenic	1.0
MEN1	O00255-1.4	Y318C	Pathogenic	1.0
MEN1	O00255-1.4	Y318D	Pathogenic	1.0
MEN1	O00255-1.4	Y318E	Pathogenic	1.0
MEN1	O00255-1.4	Y318F	Pathogenic	0.996
MEN1	O00255-1.4	Y318G	Pathogenic	1.0
MEN1	O00255-1.4	Y318H	Pathogenic	0.999
MEN1	O00255-1.4	Y318I	Pathogenic	0.999
MEN1	O00255-1.4	Y318K	Pathogenic	1.0
MEN1	O00255-1.4	Y318L	Pathogenic	0.999
MEN1	O00255-1.4	Y318M	Pathogenic	0.997
MEN1	O00255-1.4	Y318N	Pathogenic	1.0
MEN1	O00255-1.4	Y318P	Pathogenic	1.0
MEN1	O00255-1.4	Y318Q	Pathogenic	1.0
MEN1	O00255-1.4	Y318R	Pathogenic	1.0
MEN1	O00255-1.4	Y318S	Pathogenic	1.0
MEN1	O00255-1.4	Y318T	Pathogenic	1.0
MEN1	O00255-1.4	Y318V	Pathogenic	0.999
MEN1	O00255-1.4	Y318W	Pathogenic	1.0
MEN1	O00255-1.4	R319A	Pathogenic	0.897
MEN1	O00255-1.4	R319C	Pathogenic	0.876
MEN1	O00255-1.4	R319D	Neutral	0.211
MEN1	O00255-1.4	R319E	Neutral	0.071
MEN1	O00255-1.4	R319F	Neutral	0.403
MEN1	O00255-1.4	R319G	Pathogenic	0.959
MEN1	O00255-1.4	R319H	Neutral	0.12
MEN1	O00255-1.4	R319I	Pathogenic	0.611
MEN1	O00255-1.4	R319K	Neutral	0.005
MEN1	O00255-1.4	R319L	Pathogenic	0.556
MEN1	O00255-1.4	R319M	Neutral	0.355
MEN1	O00255-1.4	R319N	Neutral	0.177
MEN1	O00255-1.4	R319P	Pathogenic	0.763
MEN1	O00255-1.4	R319Q	Neutral	0.089
MEN1	O00255-1.4	R319S	Pathogenic	0.76
MEN1	O00255-1.4	R319T	Pathogenic	0.534
MEN1	O00255-1.4	R319V	Pathogenic	0.715
MEN1	O00255-1.4	R319W	Pathogenic	0.624
MEN1	O00255-1.4	R319Y	Neutral	0.096
MEN1	O00255-1.4	D320A	Pathogenic	0.954
MEN1	O00255-1.4	D320C	Pathogenic	0.941
MEN1	O00255-1.4	D320E	Pathogenic	0.693
MEN1	O00255-1.4	D320F	Pathogenic	0.999
MEN1	O00255-1.4	D320G	Pathogenic	0.98
MEN1	O00255-1.4	D320H	Pathogenic	0.949
MEN1	O00255-1.4	D320I	Pathogenic	0.998
MEN1	O00255-1.4	D320K	Pathogenic	0.956
MEN1	O00255-1.4	D320L	Pathogenic	0.998
MEN1	O00255-1.4	D320M	Pathogenic	0.995
MEN1	O00255-1.4	D320N	Neutral	0.491
MEN1	O00255-1.4	D320P	Pathogenic	0.873
MEN1	O00255-1.4	D320Q	Pathogenic	0.88
MEN1	O00255-1.4	D320R	Pathogenic	0.984
MEN1	O00255-1.4	D320S	Pathogenic	0.871
MEN1	O00255-1.4	D320T	Pathogenic	0.778
MEN1	O00255-1.4	D320V	Pathogenic	0.979
MEN1	O00255-1.4	D320W	Pathogenic	1.0
MEN1	O00255-1.4	D320Y	Pathogenic	0.998
MEN1	O00255-1.4	E321A	Pathogenic	0.849
MEN1	O00255-1.4	E321C	Pathogenic	0.829
MEN1	O00255-1.4	E321D	Neutral	0.172
MEN1	O00255-1.4	E321F	Pathogenic	0.955
MEN1	O00255-1.4	E321G	Pathogenic	0.937
MEN1	O00255-1.4	E321H	Neutral	0.253
MEN1	O00255-1.4	E321I	Pathogenic	0.905
MEN1	O00255-1.4	E321K	Neutral	0.365
MEN1	O00255-1.4	E321L	Pathogenic	0.89
MEN1	O00255-1.4	E321M	Pathogenic	0.78
MEN1	O00255-1.4	E321N	Neutral	0.122
MEN1	O00255-1.4	E321P	Pathogenic	0.662
MEN1	O00255-1.4	E321Q	Neutral	0.112
MEN1	O00255-1.4	E321R	Pathogenic	0.623
MEN1	O00255-1.4	E321S	Pathogenic	0.659
MEN1	O00255-1.4	E321T	Neutral	0.426
MEN1	O00255-1.4	E321V	Pathogenic	0.604
MEN1	O00255-1.4	E321W	Pathogenic	0.997
MEN1	O00255-1.4	E321Y	Pathogenic	0.891
MEN1	O00255-1.4	H322A	Pathogenic	1.0
MEN1	O00255-1.4	H322C	Pathogenic	1.0
MEN1	O00255-1.4	H322D	Pathogenic	1.0
MEN1	O00255-1.4	H322E	Pathogenic	0.999
MEN1	O00255-1.4	H322F	Pathogenic	1.0
MEN1	O00255-1.4	H322G	Pathogenic	1.0
MEN1	O00255-1.4	H322I	Pathogenic	1.0
MEN1	O00255-1.4	H322K	Pathogenic	1.0
MEN1	O00255-1.4	H322L	Pathogenic	1.0
MEN1	O00255-1.4	H322M	Pathogenic	0.999
MEN1	O00255-1.4	H322N	Pathogenic	1.0
MEN1	O00255-1.4	H322P	Pathogenic	1.0
MEN1	O00255-1.4	H322Q	Pathogenic	0.997
MEN1	O00255-1.4	H322R	Pathogenic	1.0
MEN1	O00255-1.4	H322S	Pathogenic	1.0
MEN1	O00255-1.4	H322T	Pathogenic	0.999
MEN1	O00255-1.4	H322V	Pathogenic	1.0
MEN1	O00255-1.4	H322W	Pathogenic	1.0
MEN1	O00255-1.4	H322Y	Pathogenic	1.0
MEN1	O00255-1.4	I323A	Pathogenic	0.999
MEN1	O00255-1.4	I323C	Pathogenic	0.992
MEN1	O00255-1.4	I323D	Pathogenic	0.999
MEN1	O00255-1.4	I323E	Pathogenic	0.997
MEN1	O00255-1.4	I323F	Pathogenic	0.815
MEN1	O00255-1.4	I323G	Pathogenic	1.0
MEN1	O00255-1.4	I323H	Pathogenic	0.982
MEN1	O00255-1.4	I323K	Pathogenic	0.998
MEN1	O00255-1.4	I323L	Pathogenic	0.665
MEN1	O00255-1.4	I323M	Pathogenic	0.819
MEN1	O00255-1.4	I323N	Pathogenic	0.999
MEN1	O00255-1.4	I323P	Pathogenic	0.994
MEN1	O00255-1.4	I323Q	Pathogenic	0.992
MEN1	O00255-1.4	I323R	Pathogenic	0.999
MEN1	O00255-1.4	I323S	Pathogenic	0.999
MEN1	O00255-1.4	I323T	Pathogenic	0.996
MEN1	O00255-1.4	I323V	Pathogenic	0.944
MEN1	O00255-1.4	I323W	Pathogenic	0.989
MEN1	O00255-1.4	I323Y	Pathogenic	0.966
MEN1	O00255-1.4	Y324A	Pathogenic	1.0
MEN1	O00255-1.4	Y324C	Pathogenic	1.0
MEN1	O00255-1.4	Y324D	Pathogenic	1.0
MEN1	O00255-1.4	Y324E	Pathogenic	1.0
MEN1	O00255-1.4	Y324F	Pathogenic	0.998
MEN1	O00255-1.4	Y324G	Pathogenic	1.0
MEN1	O00255-1.4	Y324H	Pathogenic	0.999
MEN1	O00255-1.4	Y324I	Pathogenic	0.999
MEN1	O00255-1.4	Y324K	Pathogenic	1.0
MEN1	O00255-1.4	Y324L	Pathogenic	0.999
MEN1	O00255-1.4	Y324M	Pathogenic	0.998
MEN1	O00255-1.4	Y324N	Pathogenic	1.0
MEN1	O00255-1.4	Y324P	Pathogenic	1.0
MEN1	O00255-1.4	Y324Q	Pathogenic	1.0
MEN1	O00255-1.4	Y324R	Pathogenic	1.0
MEN1	O00255-1.4	Y324S	Pathogenic	1.0
MEN1	O00255-1.4	Y324T	Pathogenic	1.0
MEN1	O00255-1.4	Y324V	Pathogenic	1.0
MEN1	O00255-1.4	Y324W	Pathogenic	1.0
MEN1	O00255-1.4	P325A	Pathogenic	0.996
MEN1	O00255-1.4	P325C	Pathogenic	0.981
MEN1	O00255-1.4	P325D	Pathogenic	0.996
MEN1	O00255-1.4	P325E	Pathogenic	0.999
MEN1	O00255-1.4	P325F	Pathogenic	1.0
MEN1	O00255-1.4	P325G	Pathogenic	0.999
MEN1	O00255-1.4	P325H	Pathogenic	0.998
MEN1	O00255-1.4	P325I	Pathogenic	0.999
MEN1	O00255-1.4	P325K	Pathogenic	1.0
MEN1	O00255-1.4	P325L	Pathogenic	0.999
MEN1	O00255-1.4	P325M	Pathogenic	0.999
MEN1	O00255-1.4	P325N	Pathogenic	0.997
MEN1	O00255-1.4	P325Q	Pathogenic	0.998
MEN1	O00255-1.4	P325R	Pathogenic	1.0
MEN1	O00255-1.4	P325S	Pathogenic	0.996
MEN1	O00255-1.4	P325T	Pathogenic	0.983
MEN1	O00255-1.4	P325V	Pathogenic	0.994
MEN1	O00255-1.4	P325W	Pathogenic	1.0
MEN1	O00255-1.4	P325Y	Pathogenic	0.999
MEN1	O00255-1.4	Y326A	Pathogenic	1.0
MEN1	O00255-1.4	Y326C	Pathogenic	0.999
MEN1	O00255-1.4	Y326D	Pathogenic	1.0
MEN1	O00255-1.4	Y326E	Pathogenic	1.0
MEN1	O00255-1.4	Y326F	Pathogenic	0.991
MEN1	O00255-1.4	Y326G	Pathogenic	1.0
MEN1	O00255-1.4	Y326H	Pathogenic	0.998
MEN1	O00255-1.4	Y326I	Pathogenic	0.997
MEN1	O00255-1.4	Y326K	Pathogenic	0.999
MEN1	O00255-1.4	Y326L	Pathogenic	0.996
MEN1	O00255-1.4	Y326M	Pathogenic	0.992
MEN1	O00255-1.4	Y326N	Pathogenic	1.0
MEN1	O00255-1.4	Y326P	Pathogenic	0.999
MEN1	O00255-1.4	Y326Q	Pathogenic	0.999
MEN1	O00255-1.4	Y326R	Pathogenic	0.999
MEN1	O00255-1.4	Y326S	Pathogenic	1.0
MEN1	O00255-1.4	Y326T	Pathogenic	1.0
MEN1	O00255-1.4	Y326V	Pathogenic	0.998
MEN1	O00255-1.4	Y326W	Pathogenic	0.999
MEN1	O00255-1.4	M327A	Pathogenic	0.999
MEN1	O00255-1.4	M327C	Pathogenic	0.991
MEN1	O00255-1.4	M327D	Pathogenic	0.999
MEN1	O00255-1.4	M327E	Pathogenic	0.997
MEN1	O00255-1.4	M327F	Pathogenic	0.958
MEN1	O00255-1.4	M327G	Pathogenic	1.0
MEN1	O00255-1.4	M327H	Pathogenic	0.977
MEN1	O00255-1.4	M327I	Pathogenic	0.907
MEN1	O00255-1.4	M327K	Pathogenic	0.997
MEN1	O00255-1.4	M327L	Pathogenic	0.886
MEN1	O00255-1.4	M327N	Pathogenic	0.999
MEN1	O00255-1.4	M327P	Pathogenic	0.993
MEN1	O00255-1.4	M327Q	Pathogenic	0.989
MEN1	O00255-1.4	M327R	Pathogenic	0.999
MEN1	O00255-1.4	M327S	Pathogenic	0.999
MEN1	O00255-1.4	M327T	Pathogenic	0.995
MEN1	O00255-1.4	M327V	Pathogenic	0.942
MEN1	O00255-1.4	M327W	Pathogenic	0.998
MEN1	O00255-1.4	M327Y	Pathogenic	0.96
MEN1	O00255-1.4	Y328A	Pathogenic	1.0
MEN1	O00255-1.4	Y328C	Pathogenic	1.0
MEN1	O00255-1.4	Y328D	Pathogenic	1.0
MEN1	O00255-1.4	Y328E	Pathogenic	1.0
MEN1	O00255-1.4	Y328F	Pathogenic	0.996
MEN1	O00255-1.4	Y328G	Pathogenic	1.0
MEN1	O00255-1.4	Y328H	Pathogenic	0.999
MEN1	O00255-1.4	Y328I	Pathogenic	0.999
MEN1	O00255-1.4	Y328K	Pathogenic	1.0
MEN1	O00255-1.4	Y328L	Pathogenic	0.998
MEN1	O00255-1.4	Y328M	Pathogenic	0.997
MEN1	O00255-1.4	Y328N	Pathogenic	1.0
MEN1	O00255-1.4	Y328P	Pathogenic	1.0
MEN1	O00255-1.4	Y328Q	Pathogenic	1.0
MEN1	O00255-1.4	Y328R	Pathogenic	1.0
MEN1	O00255-1.4	Y328S	Pathogenic	1.0
MEN1	O00255-1.4	Y328T	Pathogenic	1.0
MEN1	O00255-1.4	Y328V	Pathogenic	0.999
MEN1	O00255-1.4	Y328W	Pathogenic	0.999
MEN1	O00255-1.4	L329A	Pathogenic	0.998
MEN1	O00255-1.4	L329C	Pathogenic	0.978
MEN1	O00255-1.4	L329D	Pathogenic	0.998
MEN1	O00255-1.4	L329E	Pathogenic	0.992
MEN1	O00255-1.4	L329F	Pathogenic	0.666
MEN1	O00255-1.4	L329G	Pathogenic	1.0
MEN1	O00255-1.4	L329H	Pathogenic	0.948
MEN1	O00255-1.4	L329I	Neutral	0.443
MEN1	O00255-1.4	L329K	Pathogenic	0.994
MEN1	O00255-1.4	L329M	Pathogenic	0.59
MEN1	O00255-1.4	L329N	Pathogenic	0.997
MEN1	O00255-1.4	L329P	Pathogenic	0.983
MEN1	O00255-1.4	L329Q	Pathogenic	0.976
MEN1	O00255-1.4	L329R	Pathogenic	0.998
MEN1	O00255-1.4	L329S	Pathogenic	0.998
MEN1	O00255-1.4	L329T	Pathogenic	0.988
MEN1	O00255-1.4	L329V	Pathogenic	0.866
MEN1	O00255-1.4	L329W	Pathogenic	0.975
MEN1	O00255-1.4	L329Y	Pathogenic	0.905
MEN1	O00255-1.4	A330C	Pathogenic	0.894
MEN1	O00255-1.4	A330D	Pathogenic	0.964
MEN1	O00255-1.4	A330E	Pathogenic	0.987
MEN1	O00255-1.4	A330F	Pathogenic	0.999
MEN1	O00255-1.4	A330G	Pathogenic	0.823
MEN1	O00255-1.4	A330H	Pathogenic	0.979
MEN1	O00255-1.4	A330I	Pathogenic	0.998
MEN1	O00255-1.4	A330K	Pathogenic	0.999
MEN1	O00255-1.4	A330L	Pathogenic	0.998
MEN1	O00255-1.4	A330M	Pathogenic	0.996
MEN1	O00255-1.4	A330N	Pathogenic	0.967
MEN1	O00255-1.4	A330P	Pathogenic	0.887
MEN1	O00255-1.4	A330Q	Pathogenic	0.983
MEN1	O00255-1.4	A330R	Pathogenic	1.0
MEN1	O00255-1.4	A330S	Pathogenic	0.638
MEN1	O00255-1.4	A330T	Pathogenic	0.838
MEN1	O00255-1.4	A330V	Pathogenic	0.981
MEN1	O00255-1.4	A330W	Pathogenic	1.0
MEN1	O00255-1.4	A330Y	Pathogenic	0.998
MEN1	O00255-1.4	G331A	Pathogenic	0.968
MEN1	O00255-1.4	G331C	Pathogenic	0.998
MEN1	O00255-1.4	G331D	Pathogenic	0.998
MEN1	O00255-1.4	G331E	Pathogenic	0.999
MEN1	O00255-1.4	G331F	Pathogenic	1.0
MEN1	O00255-1.4	G331H	Pathogenic	0.999
MEN1	O00255-1.4	G331I	Pathogenic	1.0
MEN1	O00255-1.4	G331K	Pathogenic	1.0
MEN1	O00255-1.4	G331L	Pathogenic	1.0
MEN1	O00255-1.4	G331M	Pathogenic	1.0
MEN1	O00255-1.4	G331N	Pathogenic	0.998
MEN1	O00255-1.4	G331P	Pathogenic	0.997
MEN1	O00255-1.4	G331Q	Pathogenic	0.999
MEN1	O00255-1.4	G331R	Pathogenic	1.0
MEN1	O00255-1.4	G331S	Pathogenic	0.968
MEN1	O00255-1.4	G331T	Pathogenic	0.995
MEN1	O00255-1.4	G331V	Pathogenic	1.0
MEN1	O00255-1.4	G331W	Pathogenic	1.0
MEN1	O00255-1.4	G331Y	Pathogenic	1.0
MEN1	O00255-1.4	Y332A	Pathogenic	1.0
MEN1	O00255-1.4	Y332C	Pathogenic	0.998
MEN1	O00255-1.4	Y332D	Pathogenic	1.0
MEN1	O00255-1.4	Y332E	Pathogenic	0.999
MEN1	O00255-1.4	Y332F	Pathogenic	0.972
MEN1	O00255-1.4	Y332G	Pathogenic	1.0
MEN1	O00255-1.4	Y332H	Pathogenic	0.992
MEN1	O00255-1.4	Y332I	Pathogenic	0.99
MEN1	O00255-1.4	Y332K	Pathogenic	0.997
MEN1	O00255-1.4	Y332L	Pathogenic	0.989
MEN1	O00255-1.4	Y332M	Pathogenic	0.976
MEN1	O00255-1.4	Y332N	Pathogenic	1.0
MEN1	O00255-1.4	Y332P	Pathogenic	0.998
MEN1	O00255-1.4	Y332Q	Pathogenic	0.997
MEN1	O00255-1.4	Y332R	Pathogenic	0.997
MEN1	O00255-1.4	Y332S	Pathogenic	1.0
MEN1	O00255-1.4	Y332T	Pathogenic	0.999
MEN1	O00255-1.4	Y332V	Pathogenic	0.994
MEN1	O00255-1.4	Y332W	Pathogenic	0.996
MEN1	O00255-1.4	H333A	Pathogenic	0.994
MEN1	O00255-1.4	H333C	Pathogenic	0.992
MEN1	O00255-1.4	H333D	Pathogenic	0.988
MEN1	O00255-1.4	H333E	Pathogenic	0.94
MEN1	O00255-1.4	H333F	Pathogenic	0.992
MEN1	O00255-1.4	H333G	Pathogenic	0.998
MEN1	O00255-1.4	H333I	Pathogenic	0.985
MEN1	O00255-1.4	H333K	Pathogenic	0.982
MEN1	O00255-1.4	H333L	Pathogenic	0.982
MEN1	O00255-1.4	H333M	Pathogenic	0.96
MEN1	O00255-1.4	H333N	Pathogenic	0.974
MEN1	O00255-1.4	H333P	Pathogenic	0.982
MEN1	O00255-1.4	H333Q	Pathogenic	0.846
MEN1	O00255-1.4	H333R	Pathogenic	0.993
MEN1	O00255-1.4	H333S	Pathogenic	0.989
MEN1	O00255-1.4	H333T	Pathogenic	0.954
MEN1	O00255-1.4	H333V	Pathogenic	0.977
MEN1	O00255-1.4	H333W	Pathogenic	1.0
MEN1	O00255-1.4	H333Y	Pathogenic	0.978
MEN1	O00255-1.4	C334A	Pathogenic	0.974
MEN1	O00255-1.4	C334D	Pathogenic	0.989
MEN1	O00255-1.4	C334E	Pathogenic	0.997
MEN1	O00255-1.4	C334F	Pathogenic	0.998
MEN1	O00255-1.4	C334G	Pathogenic	0.997
MEN1	O00255-1.4	C334H	Pathogenic	0.994
MEN1	O00255-1.4	C334I	Pathogenic	0.995
MEN1	O00255-1.4	C334K	Pathogenic	1.0
MEN1	O00255-1.4	C334L	Pathogenic	0.994
MEN1	O00255-1.4	C334M	Pathogenic	0.988
MEN1	O00255-1.4	C334N	Pathogenic	0.99
MEN1	O00255-1.4	C334P	Pathogenic	0.882
MEN1	O00255-1.4	C334Q	Pathogenic	0.995
MEN1	O00255-1.4	C334R	Pathogenic	1.0
MEN1	O00255-1.4	C334S	Pathogenic	0.978
MEN1	O00255-1.4	C334T	Pathogenic	0.946
MEN1	O00255-1.4	C334V	Pathogenic	0.951
MEN1	O00255-1.4	C334W	Pathogenic	1.0
MEN1	O00255-1.4	C334Y	Pathogenic	0.995
MEN1	O00255-1.4	R335A	Pathogenic	1.0
MEN1	O00255-1.4	R335C	Pathogenic	1.0
MEN1	O00255-1.4	R335D	Pathogenic	1.0
MEN1	O00255-1.4	R335E	Pathogenic	0.999
MEN1	O00255-1.4	R335F	Pathogenic	1.0
MEN1	O00255-1.4	R335G	Pathogenic	1.0
MEN1	O00255-1.4	R335H	Pathogenic	0.999
MEN1	O00255-1.4	R335I	Pathogenic	1.0
MEN1	O00255-1.4	R335K	Pathogenic	0.986
MEN1	O00255-1.4	R335L	Pathogenic	1.0
MEN1	O00255-1.4	R335M	Pathogenic	1.0
MEN1	O00255-1.4	R335N	Pathogenic	1.0
MEN1	O00255-1.4	R335P	Pathogenic	1.0
MEN1	O00255-1.4	R335Q	Pathogenic	0.999
MEN1	O00255-1.4	R335S	Pathogenic	1.0
MEN1	O00255-1.4	R335T	Pathogenic	1.0
MEN1	O00255-1.4	R335V	Pathogenic	1.0
MEN1	O00255-1.4	R335W	Pathogenic	1.0
MEN1	O00255-1.4	R335Y	Pathogenic	0.999
MEN1	O00255-1.4	N336A	Pathogenic	0.948
MEN1	O00255-1.4	N336C	Pathogenic	0.933
MEN1	O00255-1.4	N336D	Neutral	0.432
MEN1	O00255-1.4	N336E	Pathogenic	0.543
MEN1	O00255-1.4	N336F	Pathogenic	0.998
MEN1	O00255-1.4	N336G	Pathogenic	0.976
MEN1	O00255-1.4	N336H	Pathogenic	0.871
MEN1	O00255-1.4	N336I	Pathogenic	0.995
MEN1	O00255-1.4	N336K	Pathogenic	0.936
MEN1	O00255-1.4	N336L	Pathogenic	0.994
MEN1	O00255-1.4	N336M	Pathogenic	0.987
MEN1	O00255-1.4	N336P	Pathogenic	0.864
MEN1	O00255-1.4	N336Q	Pathogenic	0.751
MEN1	O00255-1.4	N336R	Pathogenic	0.975
MEN1	O00255-1.4	N336S	Pathogenic	0.847
MEN1	O00255-1.4	N336T	Pathogenic	0.68
MEN1	O00255-1.4	N336V	Pathogenic	0.95
MEN1	O00255-1.4	N336W	Pathogenic	1.0
MEN1	O00255-1.4	N336Y	Pathogenic	0.994
MEN1	O00255-1.4	R337A	Pathogenic	0.996
MEN1	O00255-1.4	R337C	Pathogenic	0.995
MEN1	O00255-1.4	R337D	Pathogenic	0.89
MEN1	O00255-1.4	R337E	Pathogenic	0.698
MEN1	O00255-1.4	R337F	Pathogenic	0.953
MEN1	O00255-1.4	R337G	Pathogenic	0.999
MEN1	O00255-1.4	R337H	Pathogenic	0.804
MEN1	O00255-1.4	R337I	Pathogenic	0.979
MEN1	O00255-1.4	R337K	Neutral	0.142
MEN1	O00255-1.4	R337L	Pathogenic	0.974
MEN1	O00255-1.4	R337M	Pathogenic	0.943
MEN1	O00255-1.4	R337N	Pathogenic	0.866
MEN1	O00255-1.4	R337P	Pathogenic	0.99
MEN1	O00255-1.4	R337Q	Pathogenic	0.747
MEN1	O00255-1.4	R337S	Pathogenic	0.99
MEN1	O00255-1.4	R337T	Pathogenic	0.972
MEN1	O00255-1.4	R337V	Pathogenic	0.987
MEN1	O00255-1.4	R337W	Pathogenic	0.98
MEN1	O00255-1.4	R337Y	Pathogenic	0.761
MEN1	O00255-1.4	N338A	Pathogenic	0.811
MEN1	O00255-1.4	N338C	Pathogenic	0.768
MEN1	O00255-1.4	N338D	Neutral	0.153
MEN1	O00255-1.4	N338E	Neutral	0.219
MEN1	O00255-1.4	N338F	Pathogenic	0.991
MEN1	O00255-1.4	N338G	Pathogenic	0.905
MEN1	O00255-1.4	N338H	Pathogenic	0.616
MEN1	O00255-1.4	N338I	Pathogenic	0.98
MEN1	O00255-1.4	N338K	Pathogenic	0.776
MEN1	O00255-1.4	N338L	Pathogenic	0.976
MEN1	O00255-1.4	N338M	Pathogenic	0.947
MEN1	O00255-1.4	N338P	Pathogenic	0.6
MEN1	O00255-1.4	N338Q	Neutral	0.416
MEN1	O00255-1.4	N338R	Pathogenic	0.903
MEN1	O00255-1.4	N338S	Pathogenic	0.568
MEN1	O00255-1.4	N338T	Neutral	0.335
MEN1	O00255-1.4	N338V	Pathogenic	0.818
MEN1	O00255-1.4	N338W	Pathogenic	0.999
MEN1	O00255-1.4	N338Y	Pathogenic	0.976
MEN1	O00255-1.4	V339A	Pathogenic	0.92
MEN1	O00255-1.4	V339C	Neutral	0.496
MEN1	O00255-1.4	V339D	Pathogenic	0.929
MEN1	O00255-1.4	V339E	Pathogenic	0.825
MEN1	O00255-1.4	V339F	Pathogenic	0.795
MEN1	O00255-1.4	V339G	Pathogenic	0.989
MEN1	O00255-1.4	V339H	Pathogenic	0.738
MEN1	O00255-1.4	V339I	Pathogenic	0.578
MEN1	O00255-1.4	V339K	Pathogenic	0.983
MEN1	O00255-1.4	V339L	Pathogenic	0.567
MEN1	O00255-1.4	V339M	Neutral	0.379
MEN1	O00255-1.4	V339N	Pathogenic	0.873
MEN1	O00255-1.4	V339P	Pathogenic	0.543
MEN1	O00255-1.4	V339Q	Pathogenic	0.777
MEN1	O00255-1.4	V339R	Pathogenic	0.994
MEN1	O00255-1.4	V339S	Pathogenic	0.935
MEN1	O00255-1.4	V339T	Pathogenic	0.641
MEN1	O00255-1.4	V339W	Pathogenic	0.987
MEN1	O00255-1.4	V339Y	Pathogenic	0.784
MEN1	O00255-1.4	R340A	Pathogenic	0.999
MEN1	O00255-1.4	R340C	Pathogenic	0.999
MEN1	O00255-1.4	R340D	Pathogenic	0.968
MEN1	O00255-1.4	R340E	Pathogenic	0.897
MEN1	O00255-1.4	R340F	Pathogenic	0.987
MEN1	O00255-1.4	R340G	Pathogenic	1.0
MEN1	O00255-1.4	R340H	Pathogenic	0.939
MEN1	O00255-1.4	R340I	Pathogenic	0.994
MEN1	O00255-1.4	R340K	Neutral	0.384
MEN1	O00255-1.4	R340L	Pathogenic	0.993
MEN1	O00255-1.4	R340M	Pathogenic	0.984
MEN1	O00255-1.4	R340N	Pathogenic	0.96
MEN1	O00255-1.4	R340P	Pathogenic	0.997
MEN1	O00255-1.4	R340Q	Pathogenic	0.917
MEN1	O00255-1.4	R340S	Pathogenic	0.997
MEN1	O00255-1.4	R340T	Pathogenic	0.992
MEN1	O00255-1.4	R340V	Pathogenic	0.996
MEN1	O00255-1.4	R340W	Pathogenic	0.995
MEN1	O00255-1.4	R340Y	Pathogenic	0.923
MEN1	O00255-1.4	E341A	Pathogenic	0.993
MEN1	O00255-1.4	E341C	Pathogenic	0.992
MEN1	O00255-1.4	E341D	Pathogenic	0.842
MEN1	O00255-1.4	E341F	Pathogenic	0.998
MEN1	O00255-1.4	E341G	Pathogenic	0.997
MEN1	O00255-1.4	E341H	Pathogenic	0.896
MEN1	O00255-1.4	E341I	Pathogenic	0.996
MEN1	O00255-1.4	E341K	Pathogenic	0.936
MEN1	O00255-1.4	E341L	Pathogenic	0.995
MEN1	O00255-1.4	E341M	Pathogenic	0.989
MEN1	O00255-1.4	E341N	Pathogenic	0.779
MEN1	O00255-1.4	E341P	Pathogenic	0.98
MEN1	O00255-1.4	E341Q	Pathogenic	0.762
MEN1	O00255-1.4	E341R	Pathogenic	0.977
MEN1	O00255-1.4	E341S	Pathogenic	0.98
MEN1	O00255-1.4	E341T	Pathogenic	0.95
MEN1	O00255-1.4	E341V	Pathogenic	0.975
MEN1	O00255-1.4	E341W	Pathogenic	1.0
MEN1	O00255-1.4	E341Y	Pathogenic	0.995
MEN1	O00255-1.4	A342C	Pathogenic	0.994
MEN1	O00255-1.4	A342D	Pathogenic	0.998
MEN1	O00255-1.4	A342E	Pathogenic	0.999
MEN1	O00255-1.4	A342F	Pathogenic	1.0
MEN1	O00255-1.4	A342G	Pathogenic	0.989
MEN1	O00255-1.4	A342H	Pathogenic	0.999
MEN1	O00255-1.4	A342I	Pathogenic	1.0
MEN1	O00255-1.4	A342K	Pathogenic	1.0
MEN1	O00255-1.4	A342L	Pathogenic	1.0
MEN1	O00255-1.4	A342M	Pathogenic	1.0
MEN1	O00255-1.4	A342N	Pathogenic	0.998
MEN1	O00255-1.4	A342P	Pathogenic	0.993
MEN1	O00255-1.4	A342Q	Pathogenic	0.999
MEN1	O00255-1.4	A342R	Pathogenic	1.0
MEN1	O00255-1.4	A342S	Pathogenic	0.97
MEN1	O00255-1.4	A342T	Pathogenic	0.99
MEN1	O00255-1.4	A342V	Pathogenic	0.999
MEN1	O00255-1.4	A342W	Pathogenic	1.0
MEN1	O00255-1.4	A342Y	Pathogenic	1.0
MEN1	O00255-1.4	L343A	Pathogenic	0.997
MEN1	O00255-1.4	L343C	Pathogenic	0.965
MEN1	O00255-1.4	L343D	Pathogenic	0.997
MEN1	O00255-1.4	L343E	Pathogenic	0.987
MEN1	O00255-1.4	L343F	Pathogenic	0.551
MEN1	O00255-1.4	L343G	Pathogenic	1.0
MEN1	O00255-1.4	L343H	Pathogenic	0.918
MEN1	O00255-1.4	L343I	Neutral	0.329
MEN1	O00255-1.4	L343K	Pathogenic	0.99
MEN1	O00255-1.4	L343M	Neutral	0.47
MEN1	O00255-1.4	L343N	Pathogenic	0.995
MEN1	O00255-1.4	L343P	Pathogenic	0.972
MEN1	O00255-1.4	L343Q	Pathogenic	0.962
MEN1	O00255-1.4	L343R	Pathogenic	0.996
MEN1	O00255-1.4	L343S	Pathogenic	0.997
MEN1	O00255-1.4	L343T	Pathogenic	0.981
MEN1	O00255-1.4	L343V	Pathogenic	0.8
MEN1	O00255-1.4	L343W	Pathogenic	0.96
MEN1	O00255-1.4	L343Y	Pathogenic	0.855
MEN1	O00255-1.4	Q344A	Neutral	0.499
MEN1	O00255-1.4	Q344C	Neutral	0.448
MEN1	O00255-1.4	Q344D	Neutral	0.139
MEN1	O00255-1.4	Q344E	Neutral	0.029
MEN1	O00255-1.4	Q344F	Pathogenic	0.641
MEN1	O00255-1.4	Q344G	Pathogenic	0.727
MEN1	O00255-1.4	Q344H	Neutral	0.028
MEN1	O00255-1.4	Q344I	Neutral	0.445
MEN1	O00255-1.4	Q344K	Neutral	0.158
MEN1	O00255-1.4	Q344L	Neutral	0.39
MEN1	O00255-1.4	Q344M	Neutral	0.209
MEN1	O00255-1.4	Q344N	Neutral	0.078
MEN1	O00255-1.4	Q344P	Neutral	0.258
MEN1	O00255-1.4	Q344R	Neutral	0.337
MEN1	O00255-1.4	Q344S	Neutral	0.255
MEN1	O00255-1.4	Q344T	Neutral	0.116
MEN1	O00255-1.4	Q344V	Neutral	0.213
MEN1	O00255-1.4	Q344W	Pathogenic	0.966
MEN1	O00255-1.4	Q344Y	Neutral	0.392
MEN1	O00255-1.4	A345C	Pathogenic	0.753
MEN1	O00255-1.4	A345D	Pathogenic	0.906
MEN1	O00255-1.4	A345E	Pathogenic	0.966
MEN1	O00255-1.4	A345F	Pathogenic	0.998
MEN1	O00255-1.4	A345G	Pathogenic	0.628
MEN1	O00255-1.4	A345H	Pathogenic	0.944
MEN1	O00255-1.4	A345I	Pathogenic	0.995
MEN1	O00255-1.4	A345K	Pathogenic	0.997
MEN1	O00255-1.4	A345L	Pathogenic	0.994
MEN1	O00255-1.4	A345M	Pathogenic	0.988
MEN1	O00255-1.4	A345N	Pathogenic	0.914
MEN1	O00255-1.4	A345P	Pathogenic	0.74
MEN1	O00255-1.4	A345Q	Pathogenic	0.954
MEN1	O00255-1.4	A345R	Pathogenic	0.999
MEN1	O00255-1.4	A345S	Neutral	0.39
MEN1	O00255-1.4	A345T	Pathogenic	0.652
MEN1	O00255-1.4	A345V	Pathogenic	0.949
MEN1	O00255-1.4	A345W	Pathogenic	1.0
MEN1	O00255-1.4	A345Y	Pathogenic	0.995
MEN1	O00255-1.4	W346A	Pathogenic	1.0
MEN1	O00255-1.4	W346C	Pathogenic	1.0
MEN1	O00255-1.4	W346D	Pathogenic	1.0
MEN1	O00255-1.4	W346E	Pathogenic	1.0
MEN1	O00255-1.4	W346F	Pathogenic	1.0
MEN1	O00255-1.4	W346G	Pathogenic	1.0
MEN1	O00255-1.4	W346H	Pathogenic	1.0
MEN1	O00255-1.4	W346I	Pathogenic	1.0
MEN1	O00255-1.4	W346K	Pathogenic	1.0
MEN1	O00255-1.4	W346L	Pathogenic	1.0
MEN1	O00255-1.4	W346M	Pathogenic	1.0
MEN1	O00255-1.4	W346N	Pathogenic	1.0
MEN1	O00255-1.4	W346P	Pathogenic	1.0
MEN1	O00255-1.4	W346Q	Pathogenic	1.0
MEN1	O00255-1.4	W346R	Pathogenic	1.0
MEN1	O00255-1.4	W346S	Pathogenic	1.0
MEN1	O00255-1.4	W346T	Pathogenic	1.0
MEN1	O00255-1.4	W346V	Pathogenic	1.0
MEN1	O00255-1.4	W346Y	Pathogenic	1.0
MEN1	O00255-1.4	A347C	Pathogenic	0.99
MEN1	O00255-1.4	A347D	Pathogenic	0.997
MEN1	O00255-1.4	A347E	Pathogenic	0.999
MEN1	O00255-1.4	A347F	Pathogenic	1.0
MEN1	O00255-1.4	A347G	Pathogenic	0.982
MEN1	O00255-1.4	A347H	Pathogenic	0.998
MEN1	O00255-1.4	A347I	Pathogenic	1.0
MEN1	O00255-1.4	A347K	Pathogenic	1.0
MEN1	O00255-1.4	A347L	Pathogenic	1.0
MEN1	O00255-1.4	A347M	Pathogenic	1.0
MEN1	O00255-1.4	A347N	Pathogenic	0.997
MEN1	O00255-1.4	A347P	Pathogenic	0.989
MEN1	O00255-1.4	A347Q	Pathogenic	0.998
MEN1	O00255-1.4	A347R	Pathogenic	1.0
MEN1	O00255-1.4	A347S	Pathogenic	0.953
MEN1	O00255-1.4	A347T	Pathogenic	0.983
MEN1	O00255-1.4	A347V	Pathogenic	0.998
MEN1	O00255-1.4	A347W	Pathogenic	1.0
MEN1	O00255-1.4	A347Y	Pathogenic	1.0
MEN1	O00255-1.4	D348A	Pathogenic	0.92
MEN1	O00255-1.4	D348C	Pathogenic	0.898
MEN1	O00255-1.4	D348E	Pathogenic	0.555
MEN1	O00255-1.4	D348F	Pathogenic	0.998
MEN1	O00255-1.4	D348G	Pathogenic	0.965
MEN1	O00255-1.4	D348H	Pathogenic	0.911
MEN1	O00255-1.4	D348I	Pathogenic	0.996
MEN1	O00255-1.4	D348K	Pathogenic	0.923
MEN1	O00255-1.4	D348L	Pathogenic	0.996
MEN1	O00255-1.4	D348M	Pathogenic	0.991
MEN1	O00255-1.4	D348N	Neutral	0.347
MEN1	O00255-1.4	D348P	Pathogenic	0.791
MEN1	O00255-1.4	D348Q	Pathogenic	0.801
MEN1	O00255-1.4	D348R	Pathogenic	0.972
MEN1	O00255-1.4	D348S	Pathogenic	0.789
MEN1	O00255-1.4	D348T	Pathogenic	0.659
MEN1	O00255-1.4	D348V	Pathogenic	0.962
MEN1	O00255-1.4	D348W	Pathogenic	1.0
MEN1	O00255-1.4	D348Y	Pathogenic	0.996
MEN1	O00255-1.4	T349A	Pathogenic	0.756
MEN1	O00255-1.4	T349C	Pathogenic	0.704
MEN1	O00255-1.4	T349D	Pathogenic	0.728
MEN1	O00255-1.4	T349E	Pathogenic	0.86
MEN1	O00255-1.4	T349F	Pathogenic	0.992
MEN1	O00255-1.4	T349G	Pathogenic	0.953
MEN1	O00255-1.4	T349H	Pathogenic	0.785
MEN1	O00255-1.4	T349I	Pathogenic	0.982
MEN1	O00255-1.4	T349K	Pathogenic	0.987
MEN1	O00255-1.4	T349L	Pathogenic	0.979
MEN1	O00255-1.4	T349M	Pathogenic	0.955
MEN1	O00255-1.4	T349N	Pathogenic	0.673
MEN1	O00255-1.4	T349P	Pathogenic	0.535
MEN1	O00255-1.4	T349Q	Pathogenic	0.819
MEN1	O00255-1.4	T349R	Pathogenic	0.995
MEN1	O00255-1.4	T349S	Pathogenic	0.734
MEN1	O00255-1.4	T349V	Pathogenic	0.827
MEN1	O00255-1.4	T349W	Pathogenic	1.0
MEN1	O00255-1.4	T349Y	Pathogenic	0.981
MEN1	O00255-1.4	A350C	Pathogenic	0.924
MEN1	O00255-1.4	A350D	Pathogenic	0.975
MEN1	O00255-1.4	A350E	Pathogenic	0.991
MEN1	O00255-1.4	A350F	Pathogenic	0.999
MEN1	O00255-1.4	A350G	Pathogenic	0.87
MEN1	O00255-1.4	A350H	Pathogenic	0.985
MEN1	O00255-1.4	A350I	Pathogenic	0.999
MEN1	O00255-1.4	A350K	Pathogenic	0.999
MEN1	O00255-1.4	A350L	Pathogenic	0.999
MEN1	O00255-1.4	A350M	Pathogenic	0.997
MEN1	O00255-1.4	A350N	Pathogenic	0.977
MEN1	O00255-1.4	A350P	Pathogenic	0.919
MEN1	O00255-1.4	A350Q	Pathogenic	0.988
MEN1	O00255-1.4	A350R	Pathogenic	1.0
MEN1	O00255-1.4	A350S	Pathogenic	0.718
MEN1	O00255-1.4	A350T	Pathogenic	0.882
MEN1	O00255-1.4	A350V	Pathogenic	0.987
MEN1	O00255-1.4	A350W	Pathogenic	1.0
MEN1	O00255-1.4	A350Y	Pathogenic	0.999
MEN1	O00255-1.4	T351A	Neutral	0.468
MEN1	O00255-1.4	T351C	Neutral	0.403
MEN1	O00255-1.4	T351D	Neutral	0.43
MEN1	O00255-1.4	T351E	Pathogenic	0.634
MEN1	O00255-1.4	T351F	Pathogenic	0.973
MEN1	O00255-1.4	T351G	Pathogenic	0.851
MEN1	O00255-1.4	T351H	Pathogenic	0.509
MEN1	O00255-1.4	T351I	Pathogenic	0.939
MEN1	O00255-1.4	T351K	Pathogenic	0.955
MEN1	O00255-1.4	T351L	Pathogenic	0.928
MEN1	O00255-1.4	T351M	Pathogenic	0.858
MEN1	O00255-1.4	T351N	Neutral	0.368
MEN1	O00255-1.4	T351P	Neutral	0.246
MEN1	O00255-1.4	T351Q	Pathogenic	0.561
MEN1	O00255-1.4	T351R	Pathogenic	0.983
MEN1	O00255-1.4	T351S	Neutral	0.439
MEN1	O00255-1.4	T351V	Pathogenic	0.574
MEN1	O00255-1.4	T351W	Pathogenic	0.998
MEN1	O00255-1.4	T351Y	Pathogenic	0.937
MEN1	O00255-1.4	V352A	Pathogenic	0.999
MEN1	O00255-1.4	V352C	Pathogenic	0.992
MEN1	O00255-1.4	V352D	Pathogenic	0.999
MEN1	O00255-1.4	V352E	Pathogenic	0.998
MEN1	O00255-1.4	V352F	Pathogenic	0.998
MEN1	O00255-1.4	V352G	Pathogenic	1.0
MEN1	O00255-1.4	V352H	Pathogenic	0.997
MEN1	O00255-1.4	V352I	Pathogenic	0.994
MEN1	O00255-1.4	V352K	Pathogenic	1.0
MEN1	O00255-1.4	V352L	Pathogenic	0.994
MEN1	O00255-1.4	V352M	Pathogenic	0.987
MEN1	O00255-1.4	V352N	Pathogenic	0.999
MEN1	O00255-1.4	V352P	Pathogenic	0.993
MEN1	O00255-1.4	V352Q	Pathogenic	0.998
MEN1	O00255-1.4	V352R	Pathogenic	1.0
MEN1	O00255-1.4	V352S	Pathogenic	0.999
MEN1	O00255-1.4	V352T	Pathogenic	0.995
MEN1	O00255-1.4	V352W	Pathogenic	1.0
MEN1	O00255-1.4	V352Y	Pathogenic	0.998
MEN1	O00255-1.4	I353A	Pathogenic	0.999
MEN1	O00255-1.4	I353C	Pathogenic	0.994
MEN1	O00255-1.4	I353D	Pathogenic	1.0
MEN1	O00255-1.4	I353E	Pathogenic	0.998
MEN1	O00255-1.4	I353F	Pathogenic	0.839
MEN1	O00255-1.4	I353G	Pathogenic	1.0
MEN1	O00255-1.4	I353H	Pathogenic	0.984
MEN1	O00255-1.4	I353K	Pathogenic	0.998
MEN1	O00255-1.4	I353L	Pathogenic	0.701
MEN1	O00255-1.4	I353M	Pathogenic	0.842
MEN1	O00255-1.4	I353N	Pathogenic	0.999
MEN1	O00255-1.4	I353P	Pathogenic	0.995
MEN1	O00255-1.4	I353Q	Pathogenic	0.993
MEN1	O00255-1.4	I353R	Pathogenic	0.999
MEN1	O00255-1.4	I353S	Pathogenic	1.0
MEN1	O00255-1.4	I353T	Pathogenic	0.997
MEN1	O00255-1.4	I353V	Pathogenic	0.952
MEN1	O00255-1.4	I353W	Pathogenic	0.99
MEN1	O00255-1.4	I353Y	Pathogenic	0.971
MEN1	O00255-1.4	Q354A	Pathogenic	0.984
MEN1	O00255-1.4	Q354C	Pathogenic	0.981
MEN1	O00255-1.4	Q354D	Pathogenic	0.911
MEN1	O00255-1.4	Q354E	Pathogenic	0.657
MEN1	O00255-1.4	Q354F	Pathogenic	0.991
MEN1	O00255-1.4	Q354G	Pathogenic	0.994
MEN1	O00255-1.4	Q354H	Pathogenic	0.643
MEN1	O00255-1.4	Q354I	Pathogenic	0.981
MEN1	O00255-1.4	Q354K	Pathogenic	0.923
MEN1	O00255-1.4	Q354L	Pathogenic	0.976
MEN1	O00255-1.4	Q354M	Pathogenic	0.944
MEN1	O00255-1.4	Q354N	Pathogenic	0.843
MEN1	O00255-1.4	Q354P	Pathogenic	0.957
MEN1	O00255-1.4	Q354R	Pathogenic	0.97
MEN1	O00255-1.4	Q354S	Pathogenic	0.956
MEN1	O00255-1.4	Q354T	Pathogenic	0.893
MEN1	O00255-1.4	Q354V	Pathogenic	0.945
MEN1	O00255-1.4	Q354W	Pathogenic	0.999
MEN1	O00255-1.4	Q354Y	Pathogenic	0.976
MEN1	O00255-1.4	D355A	Pathogenic	0.593
MEN1	O00255-1.4	D355C	Pathogenic	0.528
MEN1	O00255-1.4	D355E	Neutral	0.136
MEN1	O00255-1.4	D355F	Pathogenic	0.987
MEN1	O00255-1.4	D355G	Pathogenic	0.775
MEN1	O00255-1.4	D355H	Pathogenic	0.563
MEN1	O00255-1.4	D355I	Pathogenic	0.972
MEN1	O00255-1.4	D355K	Pathogenic	0.603
MEN1	O00255-1.4	D355L	Pathogenic	0.969
MEN1	O00255-1.4	D355M	Pathogenic	0.931
MEN1	O00255-1.4	D355N	Neutral	0.063
MEN1	O00255-1.4	D355P	Neutral	0.324
MEN1	O00255-1.4	D355Q	Neutral	0.337
MEN1	O00255-1.4	D355R	Pathogenic	0.814
MEN1	O00255-1.4	D355S	Neutral	0.321
MEN1	O00255-1.4	D355T	Neutral	0.196
MEN1	O00255-1.4	D355V	Pathogenic	0.762
MEN1	O00255-1.4	D355W	Pathogenic	0.999
MEN1	O00255-1.4	D355Y	Pathogenic	0.969
MEN1	O00255-1.4	Y356A	Pathogenic	1.0
MEN1	O00255-1.4	Y356C	Pathogenic	1.0
MEN1	O00255-1.4	Y356D	Pathogenic	1.0
MEN1	O00255-1.4	Y356E	Pathogenic	1.0
MEN1	O00255-1.4	Y356F	Pathogenic	0.995
MEN1	O00255-1.4	Y356G	Pathogenic	1.0
MEN1	O00255-1.4	Y356H	Pathogenic	0.999
MEN1	O00255-1.4	Y356I	Pathogenic	0.998
MEN1	O00255-1.4	Y356K	Pathogenic	0.999
MEN1	O00255-1.4	Y356L	Pathogenic	0.998
MEN1	O00255-1.4	Y356M	Pathogenic	0.996
MEN1	O00255-1.4	Y356N	Pathogenic	1.0
MEN1	O00255-1.4	Y356P	Pathogenic	1.0
MEN1	O00255-1.4	Y356Q	Pathogenic	1.0
MEN1	O00255-1.4	Y356R	Pathogenic	0.999
MEN1	O00255-1.4	Y356S	Pathogenic	1.0
MEN1	O00255-1.4	Y356T	Pathogenic	1.0
MEN1	O00255-1.4	Y356V	Pathogenic	0.999
MEN1	O00255-1.4	Y356W	Pathogenic	0.999
MEN1	O00255-1.4	N357A	Pathogenic	0.999
MEN1	O00255-1.4	N357C	Pathogenic	0.999
MEN1	O00255-1.4	N357D	Pathogenic	0.986
MEN1	O00255-1.4	N357E	Pathogenic	0.991
MEN1	O00255-1.4	N357F	Pathogenic	1.0
MEN1	O00255-1.4	N357G	Pathogenic	1.0
MEN1	O00255-1.4	N357H	Pathogenic	0.998
MEN1	O00255-1.4	N357I	Pathogenic	1.0
MEN1	O00255-1.4	N357K	Pathogenic	0.999
MEN1	O00255-1.4	N357L	Pathogenic	1.0
MEN1	O00255-1.4	N357M	Pathogenic	1.0
MEN1	O00255-1.4	N357P	Pathogenic	0.998
MEN1	O00255-1.4	N357Q	Pathogenic	0.996
MEN1	O00255-1.4	N357R	Pathogenic	1.0
MEN1	O00255-1.4	N357S	Pathogenic	0.998
MEN1	O00255-1.4	N357T	Pathogenic	0.995
MEN1	O00255-1.4	N357V	Pathogenic	0.999
MEN1	O00255-1.4	N357W	Pathogenic	1.0
MEN1	O00255-1.4	N357Y	Pathogenic	1.0
MEN1	O00255-1.4	Y358A	Pathogenic	1.0
MEN1	O00255-1.4	Y358C	Pathogenic	1.0
MEN1	O00255-1.4	Y358D	Pathogenic	1.0
MEN1	O00255-1.4	Y358E	Pathogenic	1.0
MEN1	O00255-1.4	Y358F	Pathogenic	0.998
MEN1	O00255-1.4	Y358G	Pathogenic	1.0
MEN1	O00255-1.4	Y358H	Pathogenic	0.999
MEN1	O00255-1.4	Y358I	Pathogenic	0.999
MEN1	O00255-1.4	Y358K	Pathogenic	1.0
MEN1	O00255-1.4	Y358L	Pathogenic	0.999
MEN1	O00255-1.4	Y358M	Pathogenic	0.998
MEN1	O00255-1.4	Y358N	Pathogenic	1.0
MEN1	O00255-1.4	Y358P	Pathogenic	1.0
MEN1	O00255-1.4	Y358Q	Pathogenic	1.0
MEN1	O00255-1.4	Y358R	Pathogenic	1.0
MEN1	O00255-1.4	Y358S	Pathogenic	1.0
MEN1	O00255-1.4	Y358T	Pathogenic	1.0
MEN1	O00255-1.4	Y358V	Pathogenic	1.0
MEN1	O00255-1.4	Y358W	Pathogenic	1.0
MEN1	O00255-1.4	C359A	Pathogenic	0.98
MEN1	O00255-1.4	C359D	Pathogenic	0.992
MEN1	O00255-1.4	C359E	Pathogenic	0.997
MEN1	O00255-1.4	C359F	Pathogenic	0.998
MEN1	O00255-1.4	C359G	Pathogenic	0.998
MEN1	O00255-1.4	C359H	Pathogenic	0.995
MEN1	O00255-1.4	C359I	Pathogenic	0.996
MEN1	O00255-1.4	C359K	Pathogenic	1.0
MEN1	O00255-1.4	C359L	Pathogenic	0.996
MEN1	O00255-1.4	C359M	Pathogenic	0.991
MEN1	O00255-1.4	C359N	Pathogenic	0.993
MEN1	O00255-1.4	C359P	Pathogenic	0.909
MEN1	O00255-1.4	C359Q	Pathogenic	0.996
MEN1	O00255-1.4	C359R	Pathogenic	1.0
MEN1	O00255-1.4	C359S	Pathogenic	0.983
MEN1	O00255-1.4	C359T	Pathogenic	0.959
MEN1	O00255-1.4	C359V	Pathogenic	0.963
MEN1	O00255-1.4	C359W	Pathogenic	1.0
MEN1	O00255-1.4	C359Y	Pathogenic	0.997
MEN1	O00255-1.4	R360A	Pathogenic	1.0
MEN1	O00255-1.4	R360C	Pathogenic	1.0
MEN1	O00255-1.4	R360D	Pathogenic	1.0
MEN1	O00255-1.4	R360E	Pathogenic	0.999
MEN1	O00255-1.4	R360F	Pathogenic	1.0
MEN1	O00255-1.4	R360G	Pathogenic	1.0
MEN1	O00255-1.4	R360H	Pathogenic	0.999
MEN1	O00255-1.4	R360I	Pathogenic	1.0
MEN1	O00255-1.4	R360K	Pathogenic	0.98
MEN1	O00255-1.4	R360L	Pathogenic	1.0
MEN1	O00255-1.4	R360M	Pathogenic	1.0
MEN1	O00255-1.4	R360N	Pathogenic	0.999
MEN1	O00255-1.4	R360P	Pathogenic	1.0
MEN1	O00255-1.4	R360Q	Pathogenic	0.999
MEN1	O00255-1.4	R360S	Pathogenic	1.0
MEN1	O00255-1.4	R360T	Pathogenic	1.0
MEN1	O00255-1.4	R360V	Pathogenic	1.0
MEN1	O00255-1.4	R360W	Pathogenic	1.0
MEN1	O00255-1.4	R360Y	Pathogenic	0.999
MEN1	O00255-1.4	E361A	Pathogenic	0.994
MEN1	O00255-1.4	E361C	Pathogenic	0.993
MEN1	O00255-1.4	E361D	Pathogenic	0.864
MEN1	O00255-1.4	E361F	Pathogenic	0.998
MEN1	O00255-1.4	E361G	Pathogenic	0.998
MEN1	O00255-1.4	E361H	Pathogenic	0.911
MEN1	O00255-1.4	E361I	Pathogenic	0.997
MEN1	O00255-1.4	E361K	Pathogenic	0.946
MEN1	O00255-1.4	E361L	Pathogenic	0.996
MEN1	O00255-1.4	E361M	Pathogenic	0.991
MEN1	O00255-1.4	E361N	Pathogenic	0.808
MEN1	O00255-1.4	E361P	Pathogenic	0.983
MEN1	O00255-1.4	E361Q	Pathogenic	0.792
MEN1	O00255-1.4	E361R	Pathogenic	0.98
MEN1	O00255-1.4	E361S	Pathogenic	0.983
MEN1	O00255-1.4	E361T	Pathogenic	0.957
MEN1	O00255-1.4	E361V	Pathogenic	0.979
MEN1	O00255-1.4	E361W	Pathogenic	1.0
MEN1	O00255-1.4	E361Y	Pathogenic	0.996
MEN1	O00255-1.4	D362A	Pathogenic	0.999
MEN1	O00255-1.4	D362C	Pathogenic	0.999
MEN1	O00255-1.4	D362E	Pathogenic	0.995
MEN1	O00255-1.4	D362F	Pathogenic	1.0
MEN1	O00255-1.4	D362G	Pathogenic	1.0
MEN1	O00255-1.4	D362H	Pathogenic	0.999
MEN1	O00255-1.4	D362I	Pathogenic	1.0
MEN1	O00255-1.4	D362K	Pathogenic	0.999
MEN1	O00255-1.4	D362L	Pathogenic	1.0
MEN1	O00255-1.4	D362M	Pathogenic	1.0
MEN1	O00255-1.4	D362N	Pathogenic	0.989
MEN1	O00255-1.4	D362P	Pathogenic	0.998
MEN1	O00255-1.4	D362Q	Pathogenic	0.998
MEN1	O00255-1.4	D362R	Pathogenic	1.0
MEN1	O00255-1.4	D362S	Pathogenic	0.998
MEN1	O00255-1.4	D362T	Pathogenic	0.997
MEN1	O00255-1.4	D362V	Pathogenic	1.0
MEN1	O00255-1.4	D362W	Pathogenic	1.0
MEN1	O00255-1.4	D362Y	Pathogenic	1.0
MEN1	O00255-1.4	E363A	Pathogenic	0.999
MEN1	O00255-1.4	E363C	Pathogenic	0.998
MEN1	O00255-1.4	E363D	Pathogenic	0.962
MEN1	O00255-1.4	E363F	Pathogenic	1.0
MEN1	O00255-1.4	E363G	Pathogenic	0.999
MEN1	O00255-1.4	E363H	Pathogenic	0.976
MEN1	O00255-1.4	E363I	Pathogenic	0.999
MEN1	O00255-1.4	E363K	Pathogenic	0.986
MEN1	O00255-1.4	E363L	Pathogenic	0.999
MEN1	O00255-1.4	E363M	Pathogenic	0.998
MEN1	O00255-1.4	E363N	Pathogenic	0.944
MEN1	O00255-1.4	E363P	Pathogenic	0.996
MEN1	O00255-1.4	E363Q	Pathogenic	0.938
MEN1	O00255-1.4	E363R	Pathogenic	0.995
MEN1	O00255-1.4	E363S	Pathogenic	0.996
MEN1	O00255-1.4	E363T	Pathogenic	0.989
MEN1	O00255-1.4	E363V	Pathogenic	0.995
MEN1	O00255-1.4	E363W	Pathogenic	1.0
MEN1	O00255-1.4	E363Y	Pathogenic	0.999
MEN1	O00255-1.4	E364A	Pathogenic	1.0
MEN1	O00255-1.4	E364C	Pathogenic	0.999
MEN1	O00255-1.4	E364D	Pathogenic	0.988
MEN1	O00255-1.4	E364F	Pathogenic	1.0
MEN1	O00255-1.4	E364G	Pathogenic	1.0
MEN1	O00255-1.4	E364H	Pathogenic	0.992
MEN1	O00255-1.4	E364I	Pathogenic	1.0
MEN1	O00255-1.4	E364K	Pathogenic	0.995
MEN1	O00255-1.4	E364L	Pathogenic	1.0
MEN1	O00255-1.4	E364M	Pathogenic	0.999
MEN1	O00255-1.4	E364N	Pathogenic	0.981
MEN1	O00255-1.4	E364P	Pathogenic	0.999
MEN1	O00255-1.4	E364Q	Pathogenic	0.98
MEN1	O00255-1.4	E364R	Pathogenic	0.998
MEN1	O00255-1.4	E364S	Pathogenic	0.999
MEN1	O00255-1.4	E364T	Pathogenic	0.996
MEN1	O00255-1.4	E364V	Pathogenic	0.998
MEN1	O00255-1.4	E364W	Pathogenic	1.0
MEN1	O00255-1.4	E364Y	Pathogenic	1.0
MEN1	O00255-1.4	I365A	Pathogenic	1.0
MEN1	O00255-1.4	I365C	Pathogenic	1.0
MEN1	O00255-1.4	I365D	Pathogenic	1.0
MEN1	O00255-1.4	I365E	Pathogenic	1.0
MEN1	O00255-1.4	I365F	Pathogenic	0.99
MEN1	O00255-1.4	I365G	Pathogenic	1.0
MEN1	O00255-1.4	I365H	Pathogenic	0.999
MEN1	O00255-1.4	I365K	Pathogenic	1.0
MEN1	O00255-1.4	I365L	Pathogenic	0.979
MEN1	O00255-1.4	I365M	Pathogenic	0.991
MEN1	O00255-1.4	I365N	Pathogenic	1.0
MEN1	O00255-1.4	I365P	Pathogenic	1.0
MEN1	O00255-1.4	I365Q	Pathogenic	1.0
MEN1	O00255-1.4	I365R	Pathogenic	1.0
MEN1	O00255-1.4	I365S	Pathogenic	1.0
MEN1	O00255-1.4	I365T	Pathogenic	1.0
MEN1	O00255-1.4	I365V	Pathogenic	0.997
MEN1	O00255-1.4	I365W	Pathogenic	1.0
MEN1	O00255-1.4	I365Y	Pathogenic	0.998
MEN1	O00255-1.4	Y366A	Pathogenic	1.0
MEN1	O00255-1.4	Y366C	Pathogenic	1.0
MEN1	O00255-1.4	Y366D	Pathogenic	1.0
MEN1	O00255-1.4	Y366E	Pathogenic	1.0
MEN1	O00255-1.4	Y366F	Pathogenic	0.998
MEN1	O00255-1.4	Y366G	Pathogenic	1.0
MEN1	O00255-1.4	Y366H	Pathogenic	1.0
MEN1	O00255-1.4	Y366I	Pathogenic	0.999
MEN1	O00255-1.4	Y366K	Pathogenic	1.0
MEN1	O00255-1.4	Y366L	Pathogenic	0.999
MEN1	O00255-1.4	Y366M	Pathogenic	0.998
MEN1	O00255-1.4	Y366N	Pathogenic	1.0
MEN1	O00255-1.4	Y366P	Pathogenic	1.0
MEN1	O00255-1.4	Y366Q	Pathogenic	1.0
MEN1	O00255-1.4	Y366R	Pathogenic	1.0
MEN1	O00255-1.4	Y366S	Pathogenic	1.0
MEN1	O00255-1.4	Y366T	Pathogenic	1.0
MEN1	O00255-1.4	Y366V	Pathogenic	1.0
MEN1	O00255-1.4	Y366W	Pathogenic	1.0
MEN1	O00255-1.4	K367A	Pathogenic	1.0
MEN1	O00255-1.4	K367C	Pathogenic	1.0
MEN1	O00255-1.4	K367D	Pathogenic	0.999
MEN1	O00255-1.4	K367E	Pathogenic	0.998
MEN1	O00255-1.4	K367F	Pathogenic	1.0
MEN1	O00255-1.4	K367G	Pathogenic	1.0
MEN1	O00255-1.4	K367H	Pathogenic	0.999
MEN1	O00255-1.4	K367I	Pathogenic	1.0
MEN1	O00255-1.4	K367L	Pathogenic	1.0
MEN1	O00255-1.4	K367M	Pathogenic	1.0
MEN1	O00255-1.4	K367N	Pathogenic	0.999
MEN1	O00255-1.4	K367P	Pathogenic	1.0
MEN1	O00255-1.4	K367Q	Pathogenic	0.999
MEN1	O00255-1.4	K367R	Pathogenic	0.99
MEN1	O00255-1.4	K367S	Pathogenic	1.0
MEN1	O00255-1.4	K367T	Pathogenic	1.0
MEN1	O00255-1.4	K367V	Pathogenic	1.0
MEN1	O00255-1.4	K367W	Pathogenic	1.0
MEN1	O00255-1.4	K367Y	Pathogenic	0.999
MEN1	O00255-1.4	E368A	Pathogenic	0.999
MEN1	O00255-1.4	E368C	Pathogenic	0.999
MEN1	O00255-1.4	E368D	Pathogenic	0.974
MEN1	O00255-1.4	E368F	Pathogenic	1.0
MEN1	O00255-1.4	E368G	Pathogenic	1.0
MEN1	O00255-1.4	E368H	Pathogenic	0.984
MEN1	O00255-1.4	E368I	Pathogenic	0.999
MEN1	O00255-1.4	E368K	Pathogenic	0.99
MEN1	O00255-1.4	E368L	Pathogenic	0.999
MEN1	O00255-1.4	E368M	Pathogenic	0.998
MEN1	O00255-1.4	E368N	Pathogenic	0.961
MEN1	O00255-1.4	E368P	Pathogenic	0.997
MEN1	O00255-1.4	E368Q	Pathogenic	0.957
MEN1	O00255-1.4	E368R	Pathogenic	0.997
MEN1	O00255-1.4	E368S	Pathogenic	0.997
MEN1	O00255-1.4	E368T	Pathogenic	0.992
MEN1	O00255-1.4	E368V	Pathogenic	0.996
MEN1	O00255-1.4	E368W	Pathogenic	1.0
MEN1	O00255-1.4	E368Y	Pathogenic	0.999
MEN1	O00255-1.4	F369A	Pathogenic	1.0
MEN1	O00255-1.4	F369C	Pathogenic	1.0
MEN1	O00255-1.4	F369D	Pathogenic	1.0
MEN1	O00255-1.4	F369E	Pathogenic	1.0
MEN1	O00255-1.4	F369G	Pathogenic	1.0
MEN1	O00255-1.4	F369H	Pathogenic	0.999
MEN1	O00255-1.4	F369I	Pathogenic	0.969
MEN1	O00255-1.4	F369K	Pathogenic	0.999
MEN1	O00255-1.4	F369L	Pathogenic	0.972
MEN1	O00255-1.4	F369M	Pathogenic	0.987
MEN1	O00255-1.4	F369N	Pathogenic	1.0
MEN1	O00255-1.4	F369P	Pathogenic	1.0
MEN1	O00255-1.4	F369Q	Pathogenic	1.0
MEN1	O00255-1.4	F369R	Pathogenic	1.0
MEN1	O00255-1.4	F369S	Pathogenic	1.0
MEN1	O00255-1.4	F369T	Pathogenic	1.0
MEN1	O00255-1.4	F369V	Pathogenic	0.997
MEN1	O00255-1.4	F369W	Pathogenic	0.995
MEN1	O00255-1.4	F369Y	Pathogenic	0.985
MEN1	O00255-1.4	F370A	Pathogenic	1.0
MEN1	O00255-1.4	F370C	Pathogenic	0.996
MEN1	O00255-1.4	F370D	Pathogenic	1.0
MEN1	O00255-1.4	F370E	Pathogenic	0.998
MEN1	O00255-1.4	F370G	Pathogenic	1.0
MEN1	O00255-1.4	F370H	Pathogenic	0.987
MEN1	O00255-1.4	F370I	Pathogenic	0.765
MEN1	O00255-1.4	F370K	Pathogenic	0.993
MEN1	O00255-1.4	F370L	Pathogenic	0.785
MEN1	O00255-1.4	F370M	Pathogenic	0.887
MEN1	O00255-1.4	F370N	Pathogenic	0.999
MEN1	O00255-1.4	F370P	Pathogenic	0.997
MEN1	O00255-1.4	F370Q	Pathogenic	0.995
MEN1	O00255-1.4	F370R	Pathogenic	0.998
MEN1	O00255-1.4	F370S	Pathogenic	1.0
MEN1	O00255-1.4	F370T	Pathogenic	0.998
MEN1	O00255-1.4	F370V	Pathogenic	0.972
MEN1	O00255-1.4	F370W	Pathogenic	0.957
MEN1	O00255-1.4	F370Y	Pathogenic	0.875
MEN1	O00255-1.4	E371A	Pathogenic	0.989
MEN1	O00255-1.4	E371C	Pathogenic	0.987
MEN1	O00255-1.4	E371D	Pathogenic	0.767
MEN1	O00255-1.4	E371F	Pathogenic	0.997
MEN1	O00255-1.4	E371G	Pathogenic	0.996
MEN1	O00255-1.4	E371H	Pathogenic	0.842
MEN1	O00255-1.4	E371I	Pathogenic	0.993
MEN1	O00255-1.4	E371K	Pathogenic	0.901
MEN1	O00255-1.4	E371L	Pathogenic	0.992
MEN1	O00255-1.4	E371M	Pathogenic	0.983
MEN1	O00255-1.4	E371N	Pathogenic	0.687
MEN1	O00255-1.4	E371P	Pathogenic	0.969
MEN1	O00255-1.4	E371Q	Pathogenic	0.665
MEN1	O00255-1.4	E371R	Pathogenic	0.963
MEN1	O00255-1.4	E371S	Pathogenic	0.968
MEN1	O00255-1.4	E371T	Pathogenic	0.921
MEN1	O00255-1.4	E371V	Pathogenic	0.96
MEN1	O00255-1.4	E371W	Pathogenic	1.0
MEN1	O00255-1.4	E371Y	Pathogenic	0.992
MEN1	O00255-1.4	V372A	Pathogenic	0.974
MEN1	O00255-1.4	V372C	Pathogenic	0.762
MEN1	O00255-1.4	V372D	Pathogenic	0.977
MEN1	O00255-1.4	V372E	Pathogenic	0.939
MEN1	O00255-1.4	V372F	Pathogenic	0.926
MEN1	O00255-1.4	V372G	Pathogenic	0.997
MEN1	O00255-1.4	V372H	Pathogenic	0.902
MEN1	O00255-1.4	V372I	Pathogenic	0.817
MEN1	O00255-1.4	V372K	Pathogenic	0.995
MEN1	O00255-1.4	V372L	Pathogenic	0.81
MEN1	O00255-1.4	V372M	Pathogenic	0.665
MEN1	O00255-1.4	V372N	Pathogenic	0.957
MEN1	O00255-1.4	V372P	Pathogenic	0.795
MEN1	O00255-1.4	V372Q	Pathogenic	0.919
MEN1	O00255-1.4	V372R	Pathogenic	0.998
MEN1	O00255-1.4	V372S	Pathogenic	0.979
MEN1	O00255-1.4	V372T	Pathogenic	0.853
MEN1	O00255-1.4	V372W	Pathogenic	0.996
MEN1	O00255-1.4	V372Y	Pathogenic	0.922
MEN1	O00255-1.4	A373C	Pathogenic	0.992
MEN1	O00255-1.4	A373D	Pathogenic	0.998
MEN1	O00255-1.4	A373E	Pathogenic	0.999
MEN1	O00255-1.4	A373F	Pathogenic	1.0
MEN1	O00255-1.4	A373G	Pathogenic	0.986
MEN1	O00255-1.4	A373H	Pathogenic	0.999
MEN1	O00255-1.4	A373I	Pathogenic	1.0
MEN1	O00255-1.4	A373K	Pathogenic	1.0
MEN1	O00255-1.4	A373L	Pathogenic	1.0
MEN1	O00255-1.4	A373M	Pathogenic	1.0
MEN1	O00255-1.4	A373N	Pathogenic	0.998
MEN1	O00255-1.4	A373P	Pathogenic	0.992
MEN1	O00255-1.4	A373Q	Pathogenic	0.999
MEN1	O00255-1.4	A373R	Pathogenic	1.0
MEN1	O00255-1.4	A373S	Pathogenic	0.964
MEN1	O00255-1.4	A373T	Pathogenic	0.988
MEN1	O00255-1.4	A373V	Pathogenic	0.999
MEN1	O00255-1.4	A373W	Pathogenic	1.0
MEN1	O00255-1.4	A373Y	Pathogenic	1.0
MEN1	O00255-1.4	N374A	Pathogenic	1.0
MEN1	O00255-1.4	N374C	Pathogenic	1.0
MEN1	O00255-1.4	N374D	Pathogenic	0.994
MEN1	O00255-1.4	N374E	Pathogenic	0.996
MEN1	O00255-1.4	N374F	Pathogenic	1.0
MEN1	O00255-1.4	N374G	Pathogenic	1.0
MEN1	O00255-1.4	N374H	Pathogenic	0.999
MEN1	O00255-1.4	N374I	Pathogenic	1.0
MEN1	O00255-1.4	N374K	Pathogenic	1.0
MEN1	O00255-1.4	N374L	Pathogenic	1.0
MEN1	O00255-1.4	N374M	Pathogenic	1.0
MEN1	O00255-1.4	N374P	Pathogenic	0.999
MEN1	O00255-1.4	N374Q	Pathogenic	0.999
MEN1	O00255-1.4	N374R	Pathogenic	1.0
MEN1	O00255-1.4	N374S	Pathogenic	0.999
MEN1	O00255-1.4	N374T	Pathogenic	0.998
MEN1	O00255-1.4	N374V	Pathogenic	1.0
MEN1	O00255-1.4	N374W	Pathogenic	1.0
MEN1	O00255-1.4	N374Y	Pathogenic	1.0
MEN1	O00255-1.4	D375A	Pathogenic	0.989
MEN1	O00255-1.4	D375C	Pathogenic	0.986
MEN1	O00255-1.4	D375E	Pathogenic	0.909
MEN1	O00255-1.4	D375F	Pathogenic	1.0
MEN1	O00255-1.4	D375G	Pathogenic	0.995
MEN1	O00255-1.4	D375H	Pathogenic	0.988
MEN1	O00255-1.4	D375I	Pathogenic	1.0
MEN1	O00255-1.4	D375K	Pathogenic	0.99
MEN1	O00255-1.4	D375L	Pathogenic	0.999
MEN1	O00255-1.4	D375M	Pathogenic	0.999
MEN1	O00255-1.4	D375N	Pathogenic	0.81
MEN1	O00255-1.4	D375P	Pathogenic	0.968
MEN1	O00255-1.4	D375Q	Pathogenic	0.97
MEN1	O00255-1.4	D375R	Pathogenic	0.996
MEN1	O00255-1.4	D375S	Pathogenic	0.968
MEN1	O00255-1.4	D375T	Pathogenic	0.939
MEN1	O00255-1.4	D375V	Pathogenic	0.995
MEN1	O00255-1.4	D375W	Pathogenic	1.0
MEN1	O00255-1.4	D375Y	Pathogenic	0.999
MEN1	O00255-1.4	V376A	Pathogenic	0.977
MEN1	O00255-1.4	V376C	Pathogenic	0.788
MEN1	O00255-1.4	V376D	Pathogenic	0.98
MEN1	O00255-1.4	V376E	Pathogenic	0.947
MEN1	O00255-1.4	V376F	Pathogenic	0.936
MEN1	O00255-1.4	V376G	Pathogenic	0.997
MEN1	O00255-1.4	V376H	Pathogenic	0.914
MEN1	O00255-1.4	V376I	Pathogenic	0.838
MEN1	O00255-1.4	V376K	Pathogenic	0.995
MEN1	O00255-1.4	V376L	Pathogenic	0.831
MEN1	O00255-1.4	V376M	Pathogenic	0.697
MEN1	O00255-1.4	V376N	Pathogenic	0.963
MEN1	O00255-1.4	V376P	Pathogenic	0.818
MEN1	O00255-1.4	V376Q	Pathogenic	0.929
MEN1	O00255-1.4	V376R	Pathogenic	0.998
MEN1	O00255-1.4	V376S	Pathogenic	0.982
MEN1	O00255-1.4	V376T	Pathogenic	0.87
MEN1	O00255-1.4	V376W	Pathogenic	0.996
MEN1	O00255-1.4	V376Y	Pathogenic	0.932
MEN1	O00255-1.4	I377A	Pathogenic	1.0
MEN1	O00255-1.4	I377C	Pathogenic	0.999
MEN1	O00255-1.4	I377D	Pathogenic	1.0
MEN1	O00255-1.4	I377E	Pathogenic	1.0
MEN1	O00255-1.4	I377F	Pathogenic	0.98
MEN1	O00255-1.4	I377G	Pathogenic	1.0
MEN1	O00255-1.4	I377H	Pathogenic	0.998
MEN1	O00255-1.4	I377K	Pathogenic	1.0
MEN1	O00255-1.4	I377L	Pathogenic	0.958
MEN1	O00255-1.4	I377M	Pathogenic	0.981
MEN1	O00255-1.4	I377N	Pathogenic	1.0
MEN1	O00255-1.4	I377P	Pathogenic	0.999
MEN1	O00255-1.4	I377Q	Pathogenic	0.999
MEN1	O00255-1.4	I377R	Pathogenic	1.0
MEN1	O00255-1.4	I377S	Pathogenic	1.0
MEN1	O00255-1.4	I377T	Pathogenic	1.0
MEN1	O00255-1.4	I377V	Pathogenic	0.995
MEN1	O00255-1.4	I377W	Pathogenic	0.999
MEN1	O00255-1.4	I377Y	Pathogenic	0.997
MEN1	O00255-1.4	P378A	Pathogenic	0.997
MEN1	O00255-1.4	P378C	Pathogenic	0.984
MEN1	O00255-1.4	P378D	Pathogenic	0.997
MEN1	O00255-1.4	P378E	Pathogenic	0.999
MEN1	O00255-1.4	P378F	Pathogenic	1.0
MEN1	O00255-1.4	P378G	Pathogenic	1.0
MEN1	O00255-1.4	P378H	Pathogenic	0.998
MEN1	O00255-1.4	P378I	Pathogenic	1.0
MEN1	O00255-1.4	P378K	Pathogenic	1.0
MEN1	O00255-1.4	P378L	Pathogenic	0.999
MEN1	O00255-1.4	P378M	Pathogenic	0.999
MEN1	O00255-1.4	P378N	Pathogenic	0.997
MEN1	O00255-1.4	P378Q	Pathogenic	0.999
MEN1	O00255-1.4	P378R	Pathogenic	1.0
MEN1	O00255-1.4	P378S	Pathogenic	0.997
MEN1	O00255-1.4	P378T	Pathogenic	0.986
MEN1	O00255-1.4	P378V	Pathogenic	0.995
MEN1	O00255-1.4	P378W	Pathogenic	1.0
MEN1	O00255-1.4	P378Y	Pathogenic	1.0
MEN1	O00255-1.4	N379A	Pathogenic	0.951
MEN1	O00255-1.4	N379C	Pathogenic	0.938
MEN1	O00255-1.4	N379D	Neutral	0.45
MEN1	O00255-1.4	N379E	Pathogenic	0.56
MEN1	O00255-1.4	N379F	Pathogenic	0.998
MEN1	O00255-1.4	N379G	Pathogenic	0.978
MEN1	O00255-1.4	N379H	Pathogenic	0.879
MEN1	O00255-1.4	N379I	Pathogenic	0.995
MEN1	O00255-1.4	N379K	Pathogenic	0.94
MEN1	O00255-1.4	N379L	Pathogenic	0.995
MEN1	O00255-1.4	N379M	Pathogenic	0.988
MEN1	O00255-1.4	N379P	Pathogenic	0.872
MEN1	O00255-1.4	N379Q	Pathogenic	0.764
MEN1	O00255-1.4	N379R	Pathogenic	0.977
MEN1	O00255-1.4	N379S	Pathogenic	0.856
MEN1	O00255-1.4	N379T	Pathogenic	0.696
MEN1	O00255-1.4	N379V	Pathogenic	0.953
MEN1	O00255-1.4	N379W	Pathogenic	1.0
MEN1	O00255-1.4	N379Y	Pathogenic	0.995
MEN1	O00255-1.4	L380A	Pathogenic	0.988
MEN1	O00255-1.4	L380C	Pathogenic	0.874
MEN1	O00255-1.4	L380D	Pathogenic	0.99
MEN1	O00255-1.4	L380E	Pathogenic	0.951
MEN1	O00255-1.4	L380F	Neutral	0.238
MEN1	O00255-1.4	L380G	Pathogenic	0.999
MEN1	O00255-1.4	L380H	Pathogenic	0.74
MEN1	O00255-1.4	L380I	Neutral	0.111
MEN1	O00255-1.4	L380K	Pathogenic	0.96
MEN1	O00255-1.4	L380M	Neutral	0.185
MEN1	O00255-1.4	L380N	Pathogenic	0.98
MEN1	O00255-1.4	L380P	Pathogenic	0.899
MEN1	O00255-1.4	L380Q	Pathogenic	0.865
MEN1	O00255-1.4	L380R	Pathogenic	0.985
MEN1	O00255-1.4	L380S	Pathogenic	0.99
MEN1	O00255-1.4	L380T	Pathogenic	0.93
MEN1	O00255-1.4	L380V	Pathogenic	0.504
MEN1	O00255-1.4	L380W	Pathogenic	0.858
MEN1	O00255-1.4	L380Y	Pathogenic	0.6
MEN1	O00255-1.4	L381A	Pathogenic	0.992
MEN1	O00255-1.4	L381C	Pathogenic	0.908
MEN1	O00255-1.4	L381D	Pathogenic	0.993
MEN1	O00255-1.4	L381E	Pathogenic	0.965
MEN1	O00255-1.4	L381F	Neutral	0.307
MEN1	O00255-1.4	L381G	Pathogenic	0.999
MEN1	O00255-1.4	L381H	Pathogenic	0.801
MEN1	O00255-1.4	L381I	Neutral	0.15
MEN1	O00255-1.4	L381K	Pathogenic	0.971
MEN1	O00255-1.4	L381M	Neutral	0.243
MEN1	O00255-1.4	L381N	Pathogenic	0.986
MEN1	O00255-1.4	L381P	Pathogenic	0.927
MEN1	O00255-1.4	L381Q	Pathogenic	0.901
MEN1	O00255-1.4	L381R	Pathogenic	0.989
MEN1	O00255-1.4	L381S	Pathogenic	0.993
MEN1	O00255-1.4	L381T	Pathogenic	0.95
MEN1	O00255-1.4	L381V	Pathogenic	0.59
MEN1	O00255-1.4	L381W	Pathogenic	0.895
MEN1	O00255-1.4	L381Y	Pathogenic	0.68
MEN1	O00255-1.4	K382A	Pathogenic	1.0
MEN1	O00255-1.4	K382C	Pathogenic	1.0
MEN1	O00255-1.4	K382D	Pathogenic	0.998
MEN1	O00255-1.4	K382E	Pathogenic	0.992
MEN1	O00255-1.4	K382F	Pathogenic	0.999
MEN1	O00255-1.4	K382G	Pathogenic	1.0
MEN1	O00255-1.4	K382H	Pathogenic	0.996
MEN1	O00255-1.4	K382I	Pathogenic	1.0
MEN1	O00255-1.4	K382L	Pathogenic	1.0
MEN1	O00255-1.4	K382M	Pathogenic	0.999
MEN1	O00255-1.4	K382N	Pathogenic	0.997
MEN1	O00255-1.4	K382P	Pathogenic	1.0
MEN1	O00255-1.4	K382Q	Pathogenic	0.994
MEN1	O00255-1.4	K382R	Pathogenic	0.962
MEN1	O00255-1.4	K382S	Pathogenic	1.0
MEN1	O00255-1.4	K382T	Pathogenic	0.999
MEN1	O00255-1.4	K382V	Pathogenic	1.0
MEN1	O00255-1.4	K382W	Pathogenic	1.0
MEN1	O00255-1.4	K382Y	Pathogenic	0.998
MEN1	O00255-1.4	E383A	Pathogenic	0.926
MEN1	O00255-1.4	E383C	Pathogenic	0.915
MEN1	O00255-1.4	E383D	Neutral	0.316
MEN1	O00255-1.4	E383F	Pathogenic	0.979
MEN1	O00255-1.4	E383G	Pathogenic	0.971
MEN1	O00255-1.4	E383H	Neutral	0.429
MEN1	O00255-1.4	E383I	Pathogenic	0.955
MEN1	O00255-1.4	E383K	Pathogenic	0.561
MEN1	O00255-1.4	E383L	Pathogenic	0.947
MEN1	O00255-1.4	E383M	Pathogenic	0.887
MEN1	O00255-1.4	E383N	Neutral	0.235
MEN1	O00255-1.4	E383P	Pathogenic	0.813
MEN1	O00255-1.4	E383Q	Neutral	0.218
MEN1	O00255-1.4	E383R	Pathogenic	0.786
MEN1	O00255-1.4	E383S	Pathogenic	0.811
MEN1	O00255-1.4	E383T	Pathogenic	0.622
MEN1	O00255-1.4	E383V	Pathogenic	0.772
MEN1	O00255-1.4	E383W	Pathogenic	0.999
MEN1	O00255-1.4	E383Y	Pathogenic	0.948
MEN1	O00255-1.4	A384C	Neutral	0.078
MEN1	O00255-1.4	A384D	Neutral	0.21
MEN1	O00255-1.4	A384E	Neutral	0.437
MEN1	O00255-1.4	A384F	Pathogenic	0.932
MEN1	O00255-1.4	A384G	Neutral	0.045
MEN1	O00255-1.4	A384H	Neutral	0.317
MEN1	O00255-1.4	A384I	Pathogenic	0.853
MEN1	O00255-1.4	A384K	Pathogenic	0.906
MEN1	O00255-1.4	A384L	Pathogenic	0.831
MEN1	O00255-1.4	A384M	Pathogenic	0.697
MEN1	O00255-1.4	A384N	Neutral	0.227
MEN1	O00255-1.4	A384P	Neutral	0.073
MEN1	O00255-1.4	A384Q	Neutral	0.364
MEN1	O00255-1.4	A384R	Pathogenic	0.963
MEN1	O00255-1.4	A384S	Neutral	0.017
MEN1	O00255-1.4	A384T	Neutral	0.049
MEN1	O00255-1.4	A384V	Neutral	0.338
MEN1	O00255-1.4	A384W	Pathogenic	0.996
MEN1	O00255-1.4	A384Y	Pathogenic	0.848
MEN1	O00255-1.4	A385C	Pathogenic	0.515
MEN1	O00255-1.4	A385D	Pathogenic	0.77
MEN1	O00255-1.4	A385E	Pathogenic	0.907
MEN1	O00255-1.4	A385F	Pathogenic	0.994
MEN1	O00255-1.4	A385G	Neutral	0.37
MEN1	O00255-1.4	A385H	Pathogenic	0.854
MEN1	O00255-1.4	A385I	Pathogenic	0.986
MEN1	O00255-1.4	A385K	Pathogenic	0.992
MEN1	O00255-1.4	A385L	Pathogenic	0.984
MEN1	O00255-1.4	A385M	Pathogenic	0.967
MEN1	O00255-1.4	A385N	Pathogenic	0.787
MEN1	O00255-1.4	A385P	Neutral	0.498
MEN1	O00255-1.4	A385Q	Pathogenic	0.878
MEN1	O00255-1.4	A385R	Pathogenic	0.997
MEN1	O00255-1.4	A385S	Neutral	0.182
MEN1	O00255-1.4	A385T	Neutral	0.395
MEN1	O00255-1.4	A385V	Pathogenic	0.865
MEN1	O00255-1.4	A385W	Pathogenic	1.0
MEN1	O00255-1.4	A385Y	Pathogenic	0.986
MEN1	O00255-1.4	S386A	Neutral	0.089
MEN1	O00255-1.4	S386C	Neutral	0.356
MEN1	O00255-1.4	S386D	Neutral	0.322
MEN1	O00255-1.4	S386E	Pathogenic	0.596
MEN1	O00255-1.4	S386F	Pathogenic	0.988
MEN1	O00255-1.4	S386G	Neutral	0.206
MEN1	O00255-1.4	S386H	Pathogenic	0.603
MEN1	O00255-1.4	S386I	Pathogenic	0.974
MEN1	O00255-1.4	S386K	Pathogenic	0.948
MEN1	O00255-1.4	S386L	Pathogenic	0.97
MEN1	O00255-1.4	S386M	Pathogenic	0.934
MEN1	O00255-1.4	S386N	Neutral	0.331
MEN1	O00255-1.4	S386P	Neutral	0.327
MEN1	O00255-1.4	S386Q	Pathogenic	0.521
MEN1	O00255-1.4	S386R	Pathogenic	0.981
MEN1	O00255-1.4	S386T	Neutral	0.203
MEN1	O00255-1.4	S386V	Pathogenic	0.78
MEN1	O00255-1.4	S386W	Pathogenic	0.999
MEN1	O00255-1.4	S386Y	Pathogenic	0.972
MEN1	O00255-1.4	L387A	Pathogenic	0.868
MEN1	O00255-1.4	L387C	Neutral	0.347
MEN1	O00255-1.4	L387D	Pathogenic	0.883
MEN1	O00255-1.4	L387E	Pathogenic	0.598
MEN1	O00255-1.4	L387F	Neutral	0.023
MEN1	O00255-1.4	L387G	Pathogenic	0.982
MEN1	O00255-1.4	L387H	Neutral	0.179
MEN1	O00255-1.4	L387I	Neutral	0.009
MEN1	O00255-1.4	L387K	Pathogenic	0.648
MEN1	O00255-1.4	L387M	Neutral	0.017
MEN1	O00255-1.4	L387N	Pathogenic	0.788
MEN1	O00255-1.4	L387P	Neutral	0.406
MEN1	O00255-1.4	L387Q	Neutral	0.329
MEN1	O00255-1.4	L387R	Pathogenic	0.833
MEN1	O00255-1.4	L387S	Pathogenic	0.886
MEN1	O00255-1.4	L387T	Pathogenic	0.506
MEN1	O00255-1.4	L387V	Neutral	0.072
MEN1	O00255-1.4	L387W	Neutral	0.316
MEN1	O00255-1.4	L387Y	Neutral	0.103
MEN1	O00255-1.4	L388A	Pathogenic	0.645
MEN1	O00255-1.4	L388C	Neutral	0.128
MEN1	O00255-1.4	L388D	Pathogenic	0.676
MEN1	O00255-1.4	L388E	Neutral	0.292
MEN1	O00255-1.4	L388F	Neutral	0.007
MEN1	O00255-1.4	L388G	Pathogenic	0.937
MEN1	O00255-1.4	L388H	Neutral	0.057
MEN1	O00255-1.4	L388I	Neutral	0.003
MEN1	O00255-1.4	L388K	Neutral	0.338
MEN1	O00255-1.4	L388M	Neutral	0.005
MEN1	O00255-1.4	L388N	Pathogenic	0.507
MEN1	O00255-1.4	L388P	Neutral	0.159
MEN1	O00255-1.4	L388Q	Neutral	0.12
MEN1	O00255-1.4	L388R	Pathogenic	0.58
MEN1	O00255-1.4	L388S	Pathogenic	0.683
MEN1	O00255-1.4	L388T	Neutral	0.221
MEN1	O00255-1.4	L388V	Neutral	0.021
MEN1	O00255-1.4	L388W	Neutral	0.114
MEN1	O00255-1.4	L388Y	Neutral	0.031
MEN1	O00255-1.4	E389A	Pathogenic	0.853
MEN1	O00255-1.4	E389C	Pathogenic	0.834
MEN1	O00255-1.4	E389D	Neutral	0.178
MEN1	O00255-1.4	E389F	Pathogenic	0.956
MEN1	O00255-1.4	E389G	Pathogenic	0.939
MEN1	O00255-1.4	E389H	Neutral	0.259
MEN1	O00255-1.4	E389I	Pathogenic	0.908
MEN1	O00255-1.4	E389K	Neutral	0.373
MEN1	O00255-1.4	E389L	Pathogenic	0.893
MEN1	O00255-1.4	E389M	Pathogenic	0.786
MEN1	O00255-1.4	E389N	Neutral	0.126
MEN1	O00255-1.4	E389P	Pathogenic	0.67
MEN1	O00255-1.4	E389Q	Neutral	0.115
MEN1	O00255-1.4	E389R	Pathogenic	0.631
MEN1	O00255-1.4	E389S	Pathogenic	0.667
MEN1	O00255-1.4	E389T	Neutral	0.434
MEN1	O00255-1.4	E389V	Pathogenic	0.613
MEN1	O00255-1.4	E389W	Pathogenic	0.997
MEN1	O00255-1.4	E389Y	Pathogenic	0.894
MEN1	O00255-1.4	A390C	Neutral	0.132
MEN1	O00255-1.4	A390D	Neutral	0.325
MEN1	O00255-1.4	A390E	Pathogenic	0.584
MEN1	O00255-1.4	A390F	Pathogenic	0.961
MEN1	O00255-1.4	A390G	Neutral	0.078
MEN1	O00255-1.4	A390H	Neutral	0.456
MEN1	O00255-1.4	A390I	Pathogenic	0.913
MEN1	O00255-1.4	A390K	Pathogenic	0.945
MEN1	O00255-1.4	A390L	Pathogenic	0.899
MEN1	O00255-1.4	A390M	Pathogenic	0.806
MEN1	O00255-1.4	A390N	Neutral	0.347
MEN1	O00255-1.4	A390P	Neutral	0.125
MEN1	O00255-1.4	A390Q	Pathogenic	0.508
MEN1	O00255-1.4	A390R	Pathogenic	0.979
MEN1	O00255-1.4	A390S	Neutral	0.031
MEN1	O00255-1.4	A390T	Neutral	0.086
MEN1	O00255-1.4	A390V	Neutral	0.48
MEN1	O00255-1.4	A390W	Pathogenic	0.998
MEN1	O00255-1.4	A390Y	Pathogenic	0.91
MEN1	O00255-1.4	G391A	Neutral	0.054
MEN1	O00255-1.4	G391C	Neutral	0.46
MEN1	O00255-1.4	G391D	Neutral	0.437
MEN1	O00255-1.4	G391E	Pathogenic	0.719
MEN1	O00255-1.4	G391F	Pathogenic	0.992
MEN1	O00255-1.4	G391H	Pathogenic	0.688
MEN1	O00255-1.4	G391I	Pathogenic	0.983
MEN1	O00255-1.4	G391K	Pathogenic	0.969
MEN1	O00255-1.4	G391L	Pathogenic	0.98
MEN1	O00255-1.4	G391M	Pathogenic	0.956
MEN1	O00255-1.4	G391N	Neutral	0.447
MEN1	O00255-1.4	G391P	Neutral	0.413
MEN1	O00255-1.4	G391Q	Pathogenic	0.653
MEN1	O00255-1.4	G391R	Pathogenic	0.988
MEN1	O00255-1.4	G391S	Neutral	0.055
MEN1	O00255-1.4	G391T	Neutral	0.294
MEN1	O00255-1.4	G391V	Pathogenic	0.837
MEN1	O00255-1.4	G391W	Pathogenic	0.999
MEN1	O00255-1.4	G391Y	Pathogenic	0.98
MEN1	O00255-1.4	E392A	Pathogenic	0.687
MEN1	O00255-1.4	E392C	Pathogenic	0.655
MEN1	O00255-1.4	E392D	Neutral	0.075
MEN1	O00255-1.4	E392F	Pathogenic	0.892
MEN1	O00255-1.4	E392G	Pathogenic	0.854
MEN1	O00255-1.4	E392H	Neutral	0.117
MEN1	O00255-1.4	E392I	Pathogenic	0.788
MEN1	O00255-1.4	E392K	Neutral	0.183
MEN1	O00255-1.4	E392L	Pathogenic	0.759
MEN1	O00255-1.4	E392M	Pathogenic	0.581
MEN1	O00255-1.4	E392N	Neutral	0.051
MEN1	O00255-1.4	E392P	Neutral	0.434
MEN1	O00255-1.4	E392Q	Neutral	0.047
MEN1	O00255-1.4	E392R	Neutral	0.392
MEN1	O00255-1.4	E392S	Neutral	0.43
MEN1	O00255-1.4	E392T	Neutral	0.224
MEN1	O00255-1.4	E392V	Neutral	0.373
MEN1	O00255-1.4	E392W	Pathogenic	0.993
MEN1	O00255-1.4	E392Y	Pathogenic	0.761
MEN1	O00255-1.4	E393A	Pathogenic	0.831
MEN1	O00255-1.4	E393C	Pathogenic	0.809
MEN1	O00255-1.4	E393D	Neutral	0.154
MEN1	O00255-1.4	E393F	Pathogenic	0.949
MEN1	O00255-1.4	E393G	Pathogenic	0.929
MEN1	O00255-1.4	E393H	Neutral	0.228
MEN1	O00255-1.4	E393I	Pathogenic	0.893
MEN1	O00255-1.4	E393K	Neutral	0.335
MEN1	O00255-1.4	E393L	Pathogenic	0.876
MEN1	O00255-1.4	E393M	Pathogenic	0.756
MEN1	O00255-1.4	E393N	Neutral	0.108
MEN1	O00255-1.4	E393P	Pathogenic	0.632
MEN1	O00255-1.4	E393Q	Neutral	0.099
MEN1	O00255-1.4	E393R	Pathogenic	0.591
MEN1	O00255-1.4	E393S	Pathogenic	0.628
MEN1	O00255-1.4	E393T	Neutral	0.393
MEN1	O00255-1.4	E393V	Pathogenic	0.571
MEN1	O00255-1.4	E393W	Pathogenic	0.997
MEN1	O00255-1.4	E393Y	Pathogenic	0.877
MEN1	O00255-1.4	R394A	Pathogenic	0.996
MEN1	O00255-1.4	R394C	Pathogenic	0.995
MEN1	O00255-1.4	R394D	Pathogenic	0.879
MEN1	O00255-1.4	R394E	Pathogenic	0.675
MEN1	O00255-1.4	R394F	Pathogenic	0.948
MEN1	O00255-1.4	R394G	Pathogenic	0.998
MEN1	O00255-1.4	R394H	Pathogenic	0.787
MEN1	O00255-1.4	R394I	Pathogenic	0.977
MEN1	O00255-1.4	R394K	Neutral	0.13
MEN1	O00255-1.4	R394L	Pathogenic	0.971
MEN1	O00255-1.4	R394M	Pathogenic	0.937
MEN1	O00255-1.4	R394N	Pathogenic	0.853
MEN1	O00255-1.4	R394P	Pathogenic	0.989
MEN1	O00255-1.4	R394Q	Pathogenic	0.726
MEN1	O00255-1.4	R394S	Pathogenic	0.989
MEN1	O00255-1.4	R394T	Pathogenic	0.969
MEN1	O00255-1.4	R394V	Pathogenic	0.985
MEN1	O00255-1.4	R394W	Pathogenic	0.978
MEN1	O00255-1.4	R394Y	Pathogenic	0.741
MEN1	O00255-1.4	P395A	Neutral	0.338
MEN1	O00255-1.4	P395C	Neutral	0.099
MEN1	O00255-1.4	P395D	Neutral	0.361
MEN1	O00255-1.4	P395E	Pathogenic	0.637
MEN1	O00255-1.4	P395F	Pathogenic	0.902
MEN1	O00255-1.4	P395G	Pathogenic	0.787
MEN1	O00255-1.4	P395H	Pathogenic	0.511
MEN1	O00255-1.4	P395I	Pathogenic	0.796
MEN1	O00255-1.4	P395K	Pathogenic	0.956
MEN1	O00255-1.4	P395L	Pathogenic	0.768
MEN1	O00255-1.4	P395M	Pathogenic	0.592
MEN1	O00255-1.4	P395N	Neutral	0.399
MEN1	O00255-1.4	P395Q	Pathogenic	0.564
MEN1	O00255-1.4	P395R	Pathogenic	0.984
MEN1	O00255-1.4	P395S	Neutral	0.363
MEN1	O00255-1.4	P395T	Neutral	0.111
MEN1	O00255-1.4	P395V	Neutral	0.256
MEN1	O00255-1.4	P395W	Pathogenic	0.994
MEN1	O00255-1.4	P395Y	Pathogenic	0.78
MEN1	O00255-1.4	G396A	Neutral	0.114
MEN1	O00255-1.4	G396C	Pathogenic	0.656
MEN1	O00255-1.4	G396D	Pathogenic	0.635
MEN1	O00255-1.4	G396E	Pathogenic	0.851
MEN1	O00255-1.4	G396F	Pathogenic	0.996
MEN1	O00255-1.4	G396H	Pathogenic	0.831
MEN1	O00255-1.4	G396I	Pathogenic	0.992
MEN1	O00255-1.4	G396K	Pathogenic	0.986
MEN1	O00255-1.4	G396L	Pathogenic	0.991
MEN1	O00255-1.4	G396M	Pathogenic	0.98
MEN1	O00255-1.4	G396N	Pathogenic	0.644
MEN1	O00255-1.4	G396P	Pathogenic	0.612
MEN1	O00255-1.4	G396Q	Pathogenic	0.808
MEN1	O00255-1.4	G396R	Pathogenic	0.995
MEN1	O00255-1.4	G396S	Neutral	0.115
MEN1	O00255-1.4	G396T	Neutral	0.482
MEN1	O00255-1.4	G396V	Pathogenic	0.92
MEN1	O00255-1.4	G396W	Pathogenic	1.0
MEN1	O00255-1.4	G396Y	Pathogenic	0.991
MEN1	O00255-1.4	E397A	Neutral	0.416
MEN1	O00255-1.4	E397C	Neutral	0.381
MEN1	O00255-1.4	E397D	Neutral	0.026
MEN1	O00255-1.4	E397F	Pathogenic	0.729
MEN1	O00255-1.4	E397G	Pathogenic	0.655
MEN1	O00255-1.4	E397H	Neutral	0.041
MEN1	O00255-1.4	E397I	Pathogenic	0.547
MEN1	O00255-1.4	E397K	Neutral	0.068
MEN1	O00255-1.4	E397L	Pathogenic	0.506
MEN1	O00255-1.4	E397M	Neutral	0.31
MEN1	O00255-1.4	E397N	Neutral	0.017
MEN1	O00255-1.4	E397P	Neutral	0.199
MEN1	O00255-1.4	E397Q	Neutral	0.016
MEN1	O00255-1.4	E397R	Neutral	0.173
MEN1	O00255-1.4	E397S	Neutral	0.197
MEN1	O00255-1.4	E397T	Neutral	0.086
MEN1	O00255-1.4	E397V	Neutral	0.162
MEN1	O00255-1.4	E397W	Pathogenic	0.979
MEN1	O00255-1.4	E397Y	Pathogenic	0.508
MEN1	O00255-1.4	Q398A	Neutral	0.418
MEN1	O00255-1.4	Q398C	Neutral	0.369
MEN1	O00255-1.4	Q398D	Neutral	0.104
MEN1	O00255-1.4	Q398E	Neutral	0.021
MEN1	O00255-1.4	Q398F	Pathogenic	0.562
MEN1	O00255-1.4	Q398G	Pathogenic	0.656
MEN1	O00255-1.4	Q398H	Neutral	0.02
MEN1	O00255-1.4	Q398I	Neutral	0.366
MEN1	O00255-1.4	Q398K	Neutral	0.119
MEN1	O00255-1.4	Q398L	Neutral	0.315
MEN1	O00255-1.4	Q398M	Neutral	0.16
MEN1	O00255-1.4	Q398N	Neutral	0.057
MEN1	O00255-1.4	Q398P	Neutral	0.2
MEN1	O00255-1.4	Q398R	Neutral	0.267
MEN1	O00255-1.4	Q398S	Neutral	0.198
MEN1	O00255-1.4	Q398T	Neutral	0.086
MEN1	O00255-1.4	Q398V	Neutral	0.163
MEN1	O00255-1.4	Q398W	Pathogenic	0.954
MEN1	O00255-1.4	Q398Y	Neutral	0.317
MEN1	O00255-1.4	S399A	Neutral	0.0
MEN1	O00255-1.4	S399C	Neutral	0.001
MEN1	O00255-1.4	S399D	Neutral	0.001
MEN1	O00255-1.4	S399E	Neutral	0.004
MEN1	O00255-1.4	S399F	Neutral	0.179
MEN1	O00255-1.4	S399G	Neutral	0.001
MEN1	O00255-1.4	S399H	Neutral	0.004
MEN1	O00255-1.4	S399I	Neutral	0.089
MEN1	O00255-1.4	S399K	Neutral	0.045
MEN1	O00255-1.4	S399L	Neutral	0.077
MEN1	O00255-1.4	S399M	Neutral	0.035
MEN1	O00255-1.4	S399N	Neutral	0.001
MEN1	O00255-1.4	S399P	Neutral	0.001
MEN1	O00255-1.4	S399Q	Neutral	0.003
MEN1	O00255-1.4	S399R	Neutral	0.119
MEN1	O00255-1.4	S399T	Neutral	0.001
MEN1	O00255-1.4	S399V	Neutral	0.009
MEN1	O00255-1.4	S399W	Pathogenic	0.799
MEN1	O00255-1.4	S399Y	Neutral	0.082
MEN1	O00255-1.4	Q400A	Pathogenic	0.503
MEN1	O00255-1.4	Q400C	Neutral	0.452
MEN1	O00255-1.4	Q400D	Neutral	0.141
MEN1	O00255-1.4	Q400E	Neutral	0.03
MEN1	O00255-1.4	Q400F	Pathogenic	0.644
MEN1	O00255-1.4	Q400G	Pathogenic	0.73
MEN1	O00255-1.4	Q400H	Neutral	0.028
MEN1	O00255-1.4	Q400I	Neutral	0.449
MEN1	O00255-1.4	Q400K	Neutral	0.16
MEN1	O00255-1.4	Q400L	Neutral	0.394
MEN1	O00255-1.4	Q400M	Neutral	0.212
MEN1	O00255-1.4	Q400N	Neutral	0.079
MEN1	O00255-1.4	Q400P	Neutral	0.261
MEN1	O00255-1.4	Q400R	Neutral	0.34
MEN1	O00255-1.4	Q400S	Neutral	0.258
MEN1	O00255-1.4	Q400T	Neutral	0.118
MEN1	O00255-1.4	Q400V	Neutral	0.216
MEN1	O00255-1.4	Q400W	Pathogenic	0.967
MEN1	O00255-1.4	Q400Y	Neutral	0.396
MEN1	O00255-1.4	G401A	Neutral	0.095
MEN1	O00255-1.4	G401C	Pathogenic	0.608
MEN1	O00255-1.4	G401D	Pathogenic	0.586
MEN1	O00255-1.4	G401E	Pathogenic	0.823
MEN1	O00255-1.4	G401F	Pathogenic	0.996
MEN1	O00255-1.4	G401H	Pathogenic	0.801
MEN1	O00255-1.4	G401I	Pathogenic	0.991
MEN1	O00255-1.4	G401K	Pathogenic	0.983
MEN1	O00255-1.4	G401L	Pathogenic	0.989
MEN1	O00255-1.4	G401M	Pathogenic	0.975
MEN1	O00255-1.4	G401N	Pathogenic	0.596
MEN1	O00255-1.4	G401P	Pathogenic	0.562
MEN1	O00255-1.4	G401Q	Pathogenic	0.775
MEN1	O00255-1.4	G401R	Pathogenic	0.994
MEN1	O00255-1.4	G401S	Neutral	0.096
MEN1	O00255-1.4	G401T	Neutral	0.432
MEN1	O00255-1.4	G401V	Pathogenic	0.904
MEN1	O00255-1.4	G401W	Pathogenic	1.0
MEN1	O00255-1.4	G401Y	Pathogenic	0.989
MEN1	O00255-1.4	T402A	Neutral	0.008
MEN1	O00255-1.4	T402C	Neutral	0.006
MEN1	O00255-1.4	T402D	Neutral	0.007
MEN1	O00255-1.4	T402E	Neutral	0.015
MEN1	O00255-1.4	T402F	Neutral	0.244
MEN1	O00255-1.4	T402G	Neutral	0.048
MEN1	O00255-1.4	T402H	Neutral	0.009
MEN1	O00255-1.4	T402I	Neutral	0.12
MEN1	O00255-1.4	T402K	Neutral	0.16
MEN1	O00255-1.4	T402L	Neutral	0.104
MEN1	O00255-1.4	T402M	Neutral	0.051
MEN1	O00255-1.4	T402N	Neutral	0.005
MEN1	O00255-1.4	T402P	Neutral	0.003
MEN1	O00255-1.4	T402Q	Neutral	0.011
MEN1	O00255-1.4	T402R	Neutral	0.34
MEN1	O00255-1.4	T402S	Neutral	0.007
MEN1	O00255-1.4	T402V	Neutral	0.012
MEN1	O00255-1.4	T402W	Pathogenic	0.847
MEN1	O00255-1.4	T402Y	Neutral	0.116
MEN1	O00255-1.4	Q403A	Neutral	0.442
MEN1	O00255-1.4	Q403C	Neutral	0.393
MEN1	O00255-1.4	Q403D	Neutral	0.114
MEN1	O00255-1.4	Q403E	Neutral	0.023
MEN1	O00255-1.4	Q403F	Pathogenic	0.586
MEN1	O00255-1.4	Q403G	Pathogenic	0.679
MEN1	O00255-1.4	Q403H	Neutral	0.022
MEN1	O00255-1.4	Q403I	Neutral	0.39
MEN1	O00255-1.4	Q403K	Neutral	0.13
MEN1	O00255-1.4	Q403L	Neutral	0.337
MEN1	O00255-1.4	Q403M	Neutral	0.174
MEN1	O00255-1.4	Q403N	Neutral	0.063
MEN1	O00255-1.4	Q403P	Neutral	0.217
MEN1	O00255-1.4	Q403R	Neutral	0.288
MEN1	O00255-1.4	Q403S	Neutral	0.214
MEN1	O00255-1.4	Q403T	Neutral	0.095
MEN1	O00255-1.4	Q403V	Neutral	0.177
MEN1	O00255-1.4	Q403W	Pathogenic	0.958
MEN1	O00255-1.4	Q403Y	Neutral	0.339
MEN1	O00255-1.4	S404A	Neutral	0.005
MEN1	O00255-1.4	S404C	Neutral	0.03
MEN1	O00255-1.4	S404D	Neutral	0.026
MEN1	O00255-1.4	S404E	Neutral	0.075
MEN1	O00255-1.4	S404F	Pathogenic	0.823
MEN1	O00255-1.4	S404G	Neutral	0.014
MEN1	O00255-1.4	S404H	Neutral	0.077
MEN1	O00255-1.4	S404I	Pathogenic	0.676
MEN1	O00255-1.4	S404K	Neutral	0.5
MEN1	O00255-1.4	S404L	Pathogenic	0.639
MEN1	O00255-1.4	S404M	Neutral	0.438
MEN1	O00255-1.4	S404N	Neutral	0.027
MEN1	O00255-1.4	S404P	Neutral	0.026
MEN1	O00255-1.4	S404Q	Neutral	0.056
MEN1	O00255-1.4	S404R	Pathogenic	0.742
MEN1	O00255-1.4	S404T	Neutral	0.014
MEN1	O00255-1.4	S404V	Neutral	0.163
MEN1	O00255-1.4	S404W	Pathogenic	0.988
MEN1	O00255-1.4	S404Y	Pathogenic	0.655
MEN1	O00255-1.4	Q405A	Neutral	0.474
MEN1	O00255-1.4	Q405C	Neutral	0.424
MEN1	O00255-1.4	Q405D	Neutral	0.128
MEN1	O00255-1.4	Q405E	Neutral	0.027
MEN1	O00255-1.4	Q405F	Pathogenic	0.617
MEN1	O00255-1.4	Q405G	Pathogenic	0.706
MEN1	O00255-1.4	Q405H	Neutral	0.025
MEN1	O00255-1.4	Q405I	Neutral	0.421
MEN1	O00255-1.4	Q405K	Neutral	0.145
MEN1	O00255-1.4	Q405L	Neutral	0.367
MEN1	O00255-1.4	Q405M	Neutral	0.193
MEN1	O00255-1.4	Q405N	Neutral	0.071
MEN1	O00255-1.4	Q405P	Neutral	0.24
MEN1	O00255-1.4	Q405R	Neutral	0.315
MEN1	O00255-1.4	Q405S	Neutral	0.237
MEN1	O00255-1.4	Q405T	Neutral	0.106
MEN1	O00255-1.4	Q405V	Neutral	0.197
MEN1	O00255-1.4	Q405W	Pathogenic	0.963
MEN1	O00255-1.4	Q405Y	Neutral	0.369
MEN1	O00255-1.4	G406A	Neutral	0.018
MEN1	O00255-1.4	G406C	Neutral	0.21
MEN1	O00255-1.4	G406D	Neutral	0.195
MEN1	O00255-1.4	G406E	Neutral	0.444
MEN1	O00255-1.4	G406F	Pathogenic	0.975
MEN1	O00255-1.4	G406H	Neutral	0.408
MEN1	O00255-1.4	G406I	Pathogenic	0.948
MEN1	O00255-1.4	G406K	Pathogenic	0.908
MEN1	O00255-1.4	G406L	Pathogenic	0.939
MEN1	O00255-1.4	G406M	Pathogenic	0.872
MEN1	O00255-1.4	G406N	Neutral	0.202
MEN1	O00255-1.4	G406P	Neutral	0.18
MEN1	O00255-1.4	G406Q	Neutral	0.371
MEN1	O00255-1.4	G406R	Pathogenic	0.964
MEN1	O00255-1.4	G406S	Neutral	0.018
MEN1	O00255-1.4	G406T	Neutral	0.115
MEN1	O00255-1.4	G406V	Pathogenic	0.617
MEN1	O00255-1.4	G406W	Pathogenic	0.998
MEN1	O00255-1.4	G406Y	Pathogenic	0.94
MEN1	O00255-1.4	S407A	Neutral	0.013
MEN1	O00255-1.4	S407C	Neutral	0.068
MEN1	O00255-1.4	S407D	Neutral	0.059
MEN1	O00255-1.4	S407E	Neutral	0.162
MEN1	O00255-1.4	S407F	Pathogenic	0.917
MEN1	O00255-1.4	S407G	Neutral	0.033
MEN1	O00255-1.4	S407H	Neutral	0.166
MEN1	O00255-1.4	S407I	Pathogenic	0.833
MEN1	O00255-1.4	S407K	Pathogenic	0.705
MEN1	O00255-1.4	S407L	Pathogenic	0.809
MEN1	O00255-1.4	S407M	Pathogenic	0.65
MEN1	O00255-1.4	S407N	Neutral	0.061
MEN1	O00255-1.4	S407P	Neutral	0.06
MEN1	O00255-1.4	S407Q	Neutral	0.125
MEN1	O00255-1.4	S407R	Pathogenic	0.873
MEN1	O00255-1.4	S407T	Neutral	0.032
MEN1	O00255-1.4	S407V	Neutral	0.318
MEN1	O00255-1.4	S407W	Pathogenic	0.995
MEN1	O00255-1.4	S407Y	Pathogenic	0.819
MEN1	O00255-1.4	A408C	Neutral	0.14
MEN1	O00255-1.4	A408D	Neutral	0.339
MEN1	O00255-1.4	A408E	Pathogenic	0.599
MEN1	O00255-1.4	A408F	Pathogenic	0.963
MEN1	O00255-1.4	A408G	Neutral	0.082
MEN1	O00255-1.4	A408H	Neutral	0.471
MEN1	O00255-1.4	A408I	Pathogenic	0.918
MEN1	O00255-1.4	A408K	Pathogenic	0.949
MEN1	O00255-1.4	A408L	Pathogenic	0.904
MEN1	O00255-1.4	A408M	Pathogenic	0.816
MEN1	O00255-1.4	A408N	Neutral	0.362
MEN1	O00255-1.4	A408P	Neutral	0.132
MEN1	O00255-1.4	A408Q	Pathogenic	0.524
MEN1	O00255-1.4	A408R	Pathogenic	0.98
MEN1	O00255-1.4	A408S	Neutral	0.033
MEN1	O00255-1.4	A408T	Neutral	0.091
MEN1	O00255-1.4	A408V	Neutral	0.496
MEN1	O00255-1.4	A408W	Pathogenic	0.998
MEN1	O00255-1.4	A408Y	Pathogenic	0.915
MEN1	O00255-1.4	L409A	Pathogenic	0.991
MEN1	O00255-1.4	L409C	Pathogenic	0.899
MEN1	O00255-1.4	L409D	Pathogenic	0.992
MEN1	O00255-1.4	L409E	Pathogenic	0.961
MEN1	O00255-1.4	L409F	Neutral	0.285
MEN1	O00255-1.4	L409G	Pathogenic	0.999
MEN1	O00255-1.4	L409H	Pathogenic	0.784
MEN1	O00255-1.4	L409I	Neutral	0.137
MEN1	O00255-1.4	L409K	Pathogenic	0.968
MEN1	O00255-1.4	L409M	Neutral	0.224
MEN1	O00255-1.4	L409N	Pathogenic	0.984
MEN1	O00255-1.4	L409P	Pathogenic	0.919
MEN1	O00255-1.4	L409Q	Pathogenic	0.891
MEN1	O00255-1.4	L409R	Pathogenic	0.988
MEN1	O00255-1.4	L409S	Pathogenic	0.992
MEN1	O00255-1.4	L409T	Pathogenic	0.945
MEN1	O00255-1.4	L409V	Pathogenic	0.565
MEN1	O00255-1.4	L409W	Pathogenic	0.885
MEN1	O00255-1.4	L409Y	Pathogenic	0.657
MEN1	O00255-1.4	Q410A	Pathogenic	0.804
MEN1	O00255-1.4	Q410C	Pathogenic	0.77
MEN1	O00255-1.4	Q410D	Neutral	0.4
MEN1	O00255-1.4	Q410E	Neutral	0.111
MEN1	O00255-1.4	Q410F	Pathogenic	0.88
MEN1	O00255-1.4	Q410G	Pathogenic	0.916
MEN1	O00255-1.4	Q410H	Neutral	0.105
MEN1	O00255-1.4	Q410I	Pathogenic	0.768
MEN1	O00255-1.4	Q410K	Neutral	0.436
MEN1	O00255-1.4	Q410L	Pathogenic	0.725
MEN1	O00255-1.4	Q410M	Pathogenic	0.522
MEN1	O00255-1.4	Q410N	Neutral	0.259
MEN1	O00255-1.4	Q410P	Pathogenic	0.589
MEN1	O00255-1.4	Q410R	Pathogenic	0.676
MEN1	O00255-1.4	Q410S	Pathogenic	0.586
MEN1	O00255-1.4	Q410T	Neutral	0.352
MEN1	O00255-1.4	Q410V	Pathogenic	0.527
MEN1	O00255-1.4	Q410W	Pathogenic	0.992
MEN1	O00255-1.4	Q410Y	Pathogenic	0.727
MEN1	O00255-1.4	D411A	Pathogenic	0.955
MEN1	O00255-1.4	D411C	Pathogenic	0.943
MEN1	O00255-1.4	D411E	Pathogenic	0.698
MEN1	O00255-1.4	D411F	Pathogenic	0.999
MEN1	O00255-1.4	D411G	Pathogenic	0.981
MEN1	O00255-1.4	D411H	Pathogenic	0.95
MEN1	O00255-1.4	D411I	Pathogenic	0.998
MEN1	O00255-1.4	D411K	Pathogenic	0.957
MEN1	O00255-1.4	D411L	Pathogenic	0.998
MEN1	O00255-1.4	D411M	Pathogenic	0.995
MEN1	O00255-1.4	D411N	Neutral	0.497
MEN1	O00255-1.4	D411P	Pathogenic	0.876
MEN1	O00255-1.4	D411Q	Pathogenic	0.882
MEN1	O00255-1.4	D411R	Pathogenic	0.985
MEN1	O00255-1.4	D411S	Pathogenic	0.874
MEN1	O00255-1.4	D411T	Pathogenic	0.782
MEN1	O00255-1.4	D411V	Pathogenic	0.979
MEN1	O00255-1.4	D411W	Pathogenic	1.0
MEN1	O00255-1.4	D411Y	Pathogenic	0.998
MEN1	O00255-1.4	P412A	Pathogenic	0.642
MEN1	O00255-1.4	P412C	Neutral	0.279
MEN1	O00255-1.4	P412D	Pathogenic	0.666
MEN1	O00255-1.4	P412E	Pathogenic	0.861
MEN1	O00255-1.4	P412F	Pathogenic	0.97
MEN1	O00255-1.4	P412G	Pathogenic	0.928
MEN1	O00255-1.4	P412H	Pathogenic	0.787
MEN1	O00255-1.4	P412I	Pathogenic	0.932
MEN1	O00255-1.4	P412K	Pathogenic	0.987
MEN1	O00255-1.4	P412L	Pathogenic	0.921
MEN1	O00255-1.4	P412M	Pathogenic	0.837
MEN1	O00255-1.4	P412N	Pathogenic	0.701
MEN1	O00255-1.4	P412Q	Pathogenic	0.82
MEN1	O00255-1.4	P412R	Pathogenic	0.995
MEN1	O00255-1.4	P412S	Pathogenic	0.667
MEN1	O00255-1.4	P412T	Neutral	0.305
MEN1	O00255-1.4	P412V	Pathogenic	0.547
MEN1	O00255-1.4	P412W	Pathogenic	0.998
MEN1	O00255-1.4	P412Y	Pathogenic	0.926
MEN1	O00255-1.4	E413A	Pathogenic	0.734
MEN1	O00255-1.4	E413C	Pathogenic	0.705
MEN1	O00255-1.4	E413D	Neutral	0.093
MEN1	O00255-1.4	E413F	Pathogenic	0.912
MEN1	O00255-1.4	E413G	Pathogenic	0.88
MEN1	O00255-1.4	E413H	Neutral	0.142
MEN1	O00255-1.4	E413I	Pathogenic	0.824
MEN1	O00255-1.4	E413K	Neutral	0.22
MEN1	O00255-1.4	E413L	Pathogenic	0.799
MEN1	O00255-1.4	E413M	Pathogenic	0.635
MEN1	O00255-1.4	E413N	Neutral	0.064
MEN1	O00255-1.4	E413P	Neutral	0.49
MEN1	O00255-1.4	E413Q	Neutral	0.058
MEN1	O00255-1.4	E413R	Neutral	0.448
MEN1	O00255-1.4	E413S	Neutral	0.487
MEN1	O00255-1.4	E413T	Neutral	0.267
MEN1	O00255-1.4	E413V	Neutral	0.428
MEN1	O00255-1.4	E413W	Pathogenic	0.994
MEN1	O00255-1.4	E413Y	Pathogenic	0.8
MEN1	O00255-1.4	C414A	Pathogenic	0.996
MEN1	O00255-1.4	C414D	Pathogenic	0.999
MEN1	O00255-1.4	C414E	Pathogenic	1.0
MEN1	O00255-1.4	C414F	Pathogenic	1.0
MEN1	O00255-1.4	C414G	Pathogenic	1.0
MEN1	O00255-1.4	C414H	Pathogenic	0.999
MEN1	O00255-1.4	C414I	Pathogenic	0.999
MEN1	O00255-1.4	C414K	Pathogenic	1.0
MEN1	O00255-1.4	C414L	Pathogenic	0.999
MEN1	O00255-1.4	C414M	Pathogenic	0.998
MEN1	O00255-1.4	C414N	Pathogenic	0.999
MEN1	O00255-1.4	C414P	Pathogenic	0.983
MEN1	O00255-1.4	C414Q	Pathogenic	0.999
MEN1	O00255-1.4	C414R	Pathogenic	1.0
MEN1	O00255-1.4	C414S	Pathogenic	0.997
MEN1	O00255-1.4	C414T	Pathogenic	0.993
MEN1	O00255-1.4	C414V	Pathogenic	0.993
MEN1	O00255-1.4	C414W	Pathogenic	1.0
MEN1	O00255-1.4	C414Y	Pathogenic	0.999
MEN1	O00255-1.4	F415A	Pathogenic	1.0
MEN1	O00255-1.4	F415C	Pathogenic	0.998
MEN1	O00255-1.4	F415D	Pathogenic	1.0
MEN1	O00255-1.4	F415E	Pathogenic	0.999
MEN1	O00255-1.4	F415G	Pathogenic	1.0
MEN1	O00255-1.4	F415H	Pathogenic	0.994
MEN1	O00255-1.4	F415I	Pathogenic	0.875
MEN1	O00255-1.4	F415K	Pathogenic	0.997
MEN1	O00255-1.4	F415L	Pathogenic	0.887
MEN1	O00255-1.4	F415M	Pathogenic	0.944
MEN1	O00255-1.4	F415N	Pathogenic	1.0
MEN1	O00255-1.4	F415P	Pathogenic	0.998
MEN1	O00255-1.4	F415Q	Pathogenic	0.998
MEN1	O00255-1.4	F415R	Pathogenic	0.999
MEN1	O00255-1.4	F415S	Pathogenic	1.0
MEN1	O00255-1.4	F415T	Pathogenic	0.999
MEN1	O00255-1.4	F415V	Pathogenic	0.987
MEN1	O00255-1.4	F415W	Pathogenic	0.98
MEN1	O00255-1.4	F415Y	Pathogenic	0.938
MEN1	O00255-1.4	A416C	Pathogenic	0.892
MEN1	O00255-1.4	A416D	Pathogenic	0.963
MEN1	O00255-1.4	A416E	Pathogenic	0.987
MEN1	O00255-1.4	A416F	Pathogenic	0.999
MEN1	O00255-1.4	A416G	Pathogenic	0.819
MEN1	O00255-1.4	A416H	Pathogenic	0.978
MEN1	O00255-1.4	A416I	Pathogenic	0.998
MEN1	O00255-1.4	A416K	Pathogenic	0.999
MEN1	O00255-1.4	A416L	Pathogenic	0.998
MEN1	O00255-1.4	A416M	Pathogenic	0.996
MEN1	O00255-1.4	A416N	Pathogenic	0.966
MEN1	O00255-1.4	A416P	Pathogenic	0.885
MEN1	O00255-1.4	A416Q	Pathogenic	0.982
MEN1	O00255-1.4	A416R	Pathogenic	1.0
MEN1	O00255-1.4	A416S	Pathogenic	0.632
MEN1	O00255-1.4	A416T	Pathogenic	0.835
MEN1	O00255-1.4	A416V	Pathogenic	0.98
MEN1	O00255-1.4	A416W	Pathogenic	1.0
MEN1	O00255-1.4	A416Y	Pathogenic	0.998
MEN1	O00255-1.4	H417A	Pathogenic	0.86
MEN1	O00255-1.4	H417C	Pathogenic	0.825
MEN1	O00255-1.4	H417D	Pathogenic	0.758
MEN1	O00255-1.4	H417E	Neutral	0.383
MEN1	O00255-1.4	H417F	Pathogenic	0.835
MEN1	O00255-1.4	H417G	Pathogenic	0.959
MEN1	O00255-1.4	H417I	Pathogenic	0.719
MEN1	O00255-1.4	H417K	Pathogenic	0.679
MEN1	O00255-1.4	H417L	Pathogenic	0.684
MEN1	O00255-1.4	H417M	Neutral	0.488
MEN1	O00255-1.4	H417N	Pathogenic	0.592
MEN1	O00255-1.4	H417P	Pathogenic	0.682
MEN1	O00255-1.4	H417Q	Neutral	0.178
MEN1	O00255-1.4	H417R	Pathogenic	0.844
MEN1	O00255-1.4	H417S	Pathogenic	0.785
MEN1	O00255-1.4	H417T	Neutral	0.448
MEN1	O00255-1.4	H417V	Pathogenic	0.625
MEN1	O00255-1.4	H417W	Pathogenic	0.989
MEN1	O00255-1.4	H417Y	Pathogenic	0.632
MEN1	O00255-1.4	L418A	Pathogenic	0.995
MEN1	O00255-1.4	L418C	Pathogenic	0.941
MEN1	O00255-1.4	L418D	Pathogenic	0.996
MEN1	O00255-1.4	L418E	Pathogenic	0.978
MEN1	O00255-1.4	L418F	Neutral	0.418
MEN1	O00255-1.4	L418G	Pathogenic	0.999
MEN1	O00255-1.4	L418H	Pathogenic	0.867
MEN1	O00255-1.4	L418I	Neutral	0.223
MEN1	O00255-1.4	L418K	Pathogenic	0.982
MEN1	O00255-1.4	L418M	Neutral	0.342
MEN1	O00255-1.4	L418N	Pathogenic	0.991
MEN1	O00255-1.4	L418P	Pathogenic	0.953
MEN1	O00255-1.4	L418Q	Pathogenic	0.936
MEN1	O00255-1.4	L418R	Pathogenic	0.993
MEN1	O00255-1.4	L418S	Pathogenic	0.996
MEN1	O00255-1.4	L418T	Pathogenic	0.968
MEN1	O00255-1.4	L418V	Pathogenic	0.7
MEN1	O00255-1.4	L418W	Pathogenic	0.933
MEN1	O00255-1.4	L418Y	Pathogenic	0.775
MEN1	O00255-1.4	L419A	Pathogenic	0.998
MEN1	O00255-1.4	L419C	Pathogenic	0.974
MEN1	O00255-1.4	L419D	Pathogenic	0.998
MEN1	O00255-1.4	L419E	Pathogenic	0.991
MEN1	O00255-1.4	L419F	Pathogenic	0.629
MEN1	O00255-1.4	L419G	Pathogenic	1.0
MEN1	O00255-1.4	L419H	Pathogenic	0.939
MEN1	O00255-1.4	L419I	Neutral	0.403
MEN1	O00255-1.4	L419K	Pathogenic	0.992
MEN1	O00255-1.4	L419M	Pathogenic	0.55
MEN1	O00255-1.4	L419N	Pathogenic	0.996
MEN1	O00255-1.4	L419P	Pathogenic	0.98
MEN1	O00255-1.4	L419Q	Pathogenic	0.972
MEN1	O00255-1.4	L419R	Pathogenic	0.997
MEN1	O00255-1.4	L419S	Pathogenic	0.998
MEN1	O00255-1.4	L419T	Pathogenic	0.986
MEN1	O00255-1.4	L419V	Pathogenic	0.846
MEN1	O00255-1.4	L419W	Pathogenic	0.97
MEN1	O00255-1.4	L419Y	Pathogenic	0.89
MEN1	O00255-1.4	R420A	Pathogenic	0.999
MEN1	O00255-1.4	R420C	Pathogenic	0.999
MEN1	O00255-1.4	R420D	Pathogenic	0.973
MEN1	O00255-1.4	R420E	Pathogenic	0.913
MEN1	O00255-1.4	R420F	Pathogenic	0.989
MEN1	O00255-1.4	R420G	Pathogenic	1.0
MEN1	O00255-1.4	R420H	Pathogenic	0.949
MEN1	O00255-1.4	R420I	Pathogenic	0.995
MEN1	O00255-1.4	R420K	Neutral	0.429
MEN1	O00255-1.4	R420L	Pathogenic	0.994
MEN1	O00255-1.4	R420M	Pathogenic	0.987
MEN1	O00255-1.4	R420N	Pathogenic	0.967
MEN1	O00255-1.4	R420P	Pathogenic	0.998
MEN1	O00255-1.4	R420Q	Pathogenic	0.93
MEN1	O00255-1.4	R420S	Pathogenic	0.998
MEN1	O00255-1.4	R420T	Pathogenic	0.994
MEN1	O00255-1.4	R420V	Pathogenic	0.997
MEN1	O00255-1.4	R420W	Pathogenic	0.996
MEN1	O00255-1.4	R420Y	Pathogenic	0.935
MEN1	O00255-1.4	F421A	Pathogenic	1.0
MEN1	O00255-1.4	F421C	Pathogenic	0.998
MEN1	O00255-1.4	F421D	Pathogenic	1.0
MEN1	O00255-1.4	F421E	Pathogenic	0.999
MEN1	O00255-1.4	F421G	Pathogenic	1.0
MEN1	O00255-1.4	F421H	Pathogenic	0.994
MEN1	O00255-1.4	F421I	Pathogenic	0.88
MEN1	O00255-1.4	F421K	Pathogenic	0.997
MEN1	O00255-1.4	F421L	Pathogenic	0.892
MEN1	O00255-1.4	F421M	Pathogenic	0.946
MEN1	O00255-1.4	F421N	Pathogenic	1.0
MEN1	O00255-1.4	F421P	Pathogenic	0.998
MEN1	O00255-1.4	F421Q	Pathogenic	0.998
MEN1	O00255-1.4	F421R	Pathogenic	0.999
MEN1	O00255-1.4	F421S	Pathogenic	1.0
MEN1	O00255-1.4	F421T	Pathogenic	0.999
MEN1	O00255-1.4	F421V	Pathogenic	0.988
MEN1	O00255-1.4	F421W	Pathogenic	0.981
MEN1	O00255-1.4	F421Y	Pathogenic	0.94
MEN1	O00255-1.4	Y422A	Pathogenic	1.0
MEN1	O00255-1.4	Y422C	Pathogenic	0.997
MEN1	O00255-1.4	Y422D	Pathogenic	1.0
MEN1	O00255-1.4	Y422E	Pathogenic	0.999
MEN1	O00255-1.4	Y422F	Pathogenic	0.962
MEN1	O00255-1.4	Y422G	Pathogenic	1.0
MEN1	O00255-1.4	Y422H	Pathogenic	0.99
MEN1	O00255-1.4	Y422I	Pathogenic	0.987
MEN1	O00255-1.4	Y422K	Pathogenic	0.995
MEN1	O00255-1.4	Y422L	Pathogenic	0.984
MEN1	O00255-1.4	Y422M	Pathogenic	0.967
MEN1	O00255-1.4	Y422N	Pathogenic	1.0
MEN1	O00255-1.4	Y422P	Pathogenic	0.998
MEN1	O00255-1.4	Y422Q	Pathogenic	0.996
MEN1	O00255-1.4	Y422R	Pathogenic	0.996
MEN1	O00255-1.4	Y422S	Pathogenic	1.0
MEN1	O00255-1.4	Y422T	Pathogenic	0.998
MEN1	O00255-1.4	Y422V	Pathogenic	0.992
MEN1	O00255-1.4	Y422W	Pathogenic	0.995
MEN1	O00255-1.4	D423A	Pathogenic	0.992
MEN1	O00255-1.4	D423C	Pathogenic	0.99
MEN1	O00255-1.4	D423E	Pathogenic	0.93
MEN1	O00255-1.4	D423F	Pathogenic	1.0
MEN1	O00255-1.4	D423G	Pathogenic	0.997
MEN1	O00255-1.4	D423H	Pathogenic	0.991
MEN1	O00255-1.4	D423I	Pathogenic	1.0
MEN1	O00255-1.4	D423K	Pathogenic	0.992
MEN1	O00255-1.4	D423L	Pathogenic	1.0
MEN1	O00255-1.4	D423M	Pathogenic	0.999
MEN1	O00255-1.4	D423N	Pathogenic	0.851
MEN1	O00255-1.4	D423P	Pathogenic	0.976
MEN1	O00255-1.4	D423Q	Pathogenic	0.977
MEN1	O00255-1.4	D423R	Pathogenic	0.997
MEN1	O00255-1.4	D423S	Pathogenic	0.976
MEN1	O00255-1.4	D423T	Pathogenic	0.954
MEN1	O00255-1.4	D423V	Pathogenic	0.996
MEN1	O00255-1.4	D423W	Pathogenic	1.0
MEN1	O00255-1.4	D423Y	Pathogenic	1.0
MEN1	O00255-1.4	G424A	Pathogenic	0.842
MEN1	O00255-1.4	G424C	Pathogenic	0.987
MEN1	O00255-1.4	G424D	Pathogenic	0.986
MEN1	O00255-1.4	G424E	Pathogenic	0.996
MEN1	O00255-1.4	G424F	Pathogenic	1.0
MEN1	O00255-1.4	G424H	Pathogenic	0.995
MEN1	O00255-1.4	G424I	Pathogenic	1.0
MEN1	O00255-1.4	G424K	Pathogenic	1.0
MEN1	O00255-1.4	G424L	Pathogenic	1.0
MEN1	O00255-1.4	G424M	Pathogenic	1.0
MEN1	O00255-1.4	G424N	Pathogenic	0.987
MEN1	O00255-1.4	G424P	Pathogenic	0.985
MEN1	O00255-1.4	G424Q	Pathogenic	0.994
MEN1	O00255-1.4	G424R	Pathogenic	1.0
MEN1	O00255-1.4	G424S	Pathogenic	0.843
MEN1	O00255-1.4	G424T	Pathogenic	0.975
MEN1	O00255-1.4	G424V	Pathogenic	0.998
MEN1	O00255-1.4	G424W	Pathogenic	1.0
MEN1	O00255-1.4	G424Y	Pathogenic	1.0
MEN1	O00255-1.4	I425A	Pathogenic	1.0
MEN1	O00255-1.4	I425C	Pathogenic	0.994
MEN1	O00255-1.4	I425D	Pathogenic	1.0
MEN1	O00255-1.4	I425E	Pathogenic	0.998
MEN1	O00255-1.4	I425F	Pathogenic	0.852
MEN1	O00255-1.4	I425G	Pathogenic	1.0
MEN1	O00255-1.4	I425H	Pathogenic	0.986
MEN1	O00255-1.4	I425K	Pathogenic	0.998
MEN1	O00255-1.4	I425L	Pathogenic	0.722
MEN1	O00255-1.4	I425M	Pathogenic	0.855
MEN1	O00255-1.4	I425N	Pathogenic	0.999
MEN1	O00255-1.4	I425P	Pathogenic	0.995
MEN1	O00255-1.4	I425Q	Pathogenic	0.994
MEN1	O00255-1.4	I425R	Pathogenic	0.999
MEN1	O00255-1.4	I425S	Pathogenic	1.0
MEN1	O00255-1.4	I425T	Pathogenic	0.997
MEN1	O00255-1.4	I425V	Pathogenic	0.957
MEN1	O00255-1.4	I425W	Pathogenic	0.991
MEN1	O00255-1.4	I425Y	Pathogenic	0.974
MEN1	O00255-1.4	C426A	Pathogenic	0.998
MEN1	O00255-1.4	C426D	Pathogenic	0.999
MEN1	O00255-1.4	C426E	Pathogenic	1.0
MEN1	O00255-1.4	C426F	Pathogenic	1.0
MEN1	O00255-1.4	C426G	Pathogenic	1.0
MEN1	O00255-1.4	C426H	Pathogenic	1.0
MEN1	O00255-1.4	C426I	Pathogenic	1.0
MEN1	O00255-1.4	C426K	Pathogenic	1.0
MEN1	O00255-1.4	C426L	Pathogenic	1.0
MEN1	O00255-1.4	C426M	Pathogenic	0.999
MEN1	O00255-1.4	C426N	Pathogenic	0.999
MEN1	O00255-1.4	C426P	Pathogenic	0.992
MEN1	O00255-1.4	C426Q	Pathogenic	1.0
MEN1	O00255-1.4	C426R	Pathogenic	1.0
MEN1	O00255-1.4	C426S	Pathogenic	0.999
MEN1	O00255-1.4	C426T	Pathogenic	0.997
MEN1	O00255-1.4	C426V	Pathogenic	0.997
MEN1	O00255-1.4	C426W	Pathogenic	1.0
MEN1	O00255-1.4	C426Y	Pathogenic	1.0
MEN1	O00255-1.4	K427A	Pathogenic	0.985
MEN1	O00255-1.4	K427C	Pathogenic	0.982
MEN1	O00255-1.4	K427D	Pathogenic	0.654
MEN1	O00255-1.4	K427E	Neutral	0.352
MEN1	O00255-1.4	K427F	Pathogenic	0.835
MEN1	O00255-1.4	K427G	Pathogenic	0.994
MEN1	O00255-1.4	K427H	Pathogenic	0.521
MEN1	O00255-1.4	K427I	Pathogenic	0.922
MEN1	O00255-1.4	K427L	Pathogenic	0.904
MEN1	O00255-1.4	K427M	Pathogenic	0.805
MEN1	O00255-1.4	K427N	Pathogenic	0.617
MEN1	O00255-1.4	K427P	Pathogenic	0.958
MEN1	O00255-1.4	K427Q	Neutral	0.424
MEN1	O00255-1.4	K427R	Neutral	0.101
MEN1	O00255-1.4	K427S	Pathogenic	0.957
MEN1	O00255-1.4	K427T	Pathogenic	0.896
MEN1	O00255-1.4	K427V	Pathogenic	0.947
MEN1	O00255-1.4	K427W	Pathogenic	0.989
MEN1	O00255-1.4	K427Y	Pathogenic	0.661
MEN1	O00255-1.4	W428A	Pathogenic	1.0
MEN1	O00255-1.4	W428C	Pathogenic	1.0
MEN1	O00255-1.4	W428D	Pathogenic	1.0
MEN1	O00255-1.4	W428E	Pathogenic	1.0
MEN1	O00255-1.4	W428F	Pathogenic	0.999
MEN1	O00255-1.4	W428G	Pathogenic	1.0
MEN1	O00255-1.4	W428H	Pathogenic	1.0
MEN1	O00255-1.4	W428I	Pathogenic	0.999
MEN1	O00255-1.4	W428K	Pathogenic	1.0
MEN1	O00255-1.4	W428L	Pathogenic	1.0
MEN1	O00255-1.4	W428M	Pathogenic	1.0
MEN1	O00255-1.4	W428N	Pathogenic	1.0
MEN1	O00255-1.4	W428P	Pathogenic	1.0
MEN1	O00255-1.4	W428Q	Pathogenic	1.0
MEN1	O00255-1.4	W428R	Pathogenic	1.0
MEN1	O00255-1.4	W428S	Pathogenic	1.0
MEN1	O00255-1.4	W428T	Pathogenic	1.0
MEN1	O00255-1.4	W428V	Pathogenic	1.0
MEN1	O00255-1.4	W428Y	Pathogenic	0.999
MEN1	O00255-1.4	E429A	Pathogenic	0.992
MEN1	O00255-1.4	E429C	Pathogenic	0.991
MEN1	O00255-1.4	E429D	Pathogenic	0.828
MEN1	O00255-1.4	E429F	Pathogenic	0.998
MEN1	O00255-1.4	E429G	Pathogenic	0.997
MEN1	O00255-1.4	E429H	Pathogenic	0.887
MEN1	O00255-1.4	E429I	Pathogenic	0.995
MEN1	O00255-1.4	E429K	Pathogenic	0.93
MEN1	O00255-1.4	E429L	Pathogenic	0.995
MEN1	O00255-1.4	E429M	Pathogenic	0.988
MEN1	O00255-1.4	E429N	Pathogenic	0.762
MEN1	O00255-1.4	E429P	Pathogenic	0.978
MEN1	O00255-1.4	E429Q	Pathogenic	0.744
MEN1	O00255-1.4	E429R	Pathogenic	0.974
MEN1	O00255-1.4	E429S	Pathogenic	0.978
MEN1	O00255-1.4	E429T	Pathogenic	0.945
MEN1	O00255-1.4	E429V	Pathogenic	0.972
MEN1	O00255-1.4	E429W	Pathogenic	1.0
MEN1	O00255-1.4	E429Y	Pathogenic	0.995
MEN1	O00255-1.4	E430A	Pathogenic	0.993
MEN1	O00255-1.4	E430C	Pathogenic	0.992
MEN1	O00255-1.4	E430D	Pathogenic	0.835
MEN1	O00255-1.4	E430F	Pathogenic	0.998
MEN1	O00255-1.4	E430G	Pathogenic	0.997
MEN1	O00255-1.4	E430H	Pathogenic	0.891
MEN1	O00255-1.4	E430I	Pathogenic	0.996
MEN1	O00255-1.4	E430K	Pathogenic	0.933
MEN1	O00255-1.4	E430L	Pathogenic	0.995
MEN1	O00255-1.4	E430M	Pathogenic	0.989
MEN1	O00255-1.4	E430N	Pathogenic	0.771
MEN1	O00255-1.4	E430P	Pathogenic	0.979
MEN1	O00255-1.4	E430Q	Pathogenic	0.753
MEN1	O00255-1.4	E430R	Pathogenic	0.976
MEN1	O00255-1.4	E430S	Pathogenic	0.979
MEN1	O00255-1.4	E430T	Pathogenic	0.947
MEN1	O00255-1.4	E430V	Pathogenic	0.974
MEN1	O00255-1.4	E430W	Pathogenic	1.0
MEN1	O00255-1.4	E430Y	Pathogenic	0.995
MEN1	O00255-1.4	G431A	Pathogenic	0.75
MEN1	O00255-1.4	G431C	Pathogenic	0.978
MEN1	O00255-1.4	G431D	Pathogenic	0.976
MEN1	O00255-1.4	G431E	Pathogenic	0.993
MEN1	O00255-1.4	G431F	Pathogenic	1.0
MEN1	O00255-1.4	G431H	Pathogenic	0.991
MEN1	O00255-1.4	G431I	Pathogenic	1.0
MEN1	O00255-1.4	G431K	Pathogenic	0.999
MEN1	O00255-1.4	G431L	Pathogenic	1.0
MEN1	O00255-1.4	G431M	Pathogenic	0.999
MEN1	O00255-1.4	G431N	Pathogenic	0.977
MEN1	O00255-1.4	G431P	Pathogenic	0.974
MEN1	O00255-1.4	G431Q	Pathogenic	0.99
MEN1	O00255-1.4	G431R	Pathogenic	1.0
MEN1	O00255-1.4	G431S	Pathogenic	0.752
MEN1	O00255-1.4	G431T	Pathogenic	0.956
MEN1	O00255-1.4	G431V	Pathogenic	0.996
MEN1	O00255-1.4	G431W	Pathogenic	1.0
MEN1	O00255-1.4	G431Y	Pathogenic	1.0
MEN1	O00255-1.4	S432A	Neutral	0.48
MEN1	O00255-1.4	S432C	Pathogenic	0.84
MEN1	O00255-1.4	S432D	Pathogenic	0.818
MEN1	O00255-1.4	S432E	Pathogenic	0.933
MEN1	O00255-1.4	S432F	Pathogenic	0.999
MEN1	O00255-1.4	S432G	Pathogenic	0.711
MEN1	O00255-1.4	S432H	Pathogenic	0.935
MEN1	O00255-1.4	S432I	Pathogenic	0.997
MEN1	O00255-1.4	S432K	Pathogenic	0.994
MEN1	O00255-1.4	S432L	Pathogenic	0.997
MEN1	O00255-1.4	S432M	Pathogenic	0.993
MEN1	O00255-1.4	S432N	Pathogenic	0.824
MEN1	O00255-1.4	S432P	Pathogenic	0.821
MEN1	O00255-1.4	S432Q	Pathogenic	0.911
MEN1	O00255-1.4	S432R	Pathogenic	0.998
MEN1	O00255-1.4	S432T	Pathogenic	0.707
MEN1	O00255-1.4	S432V	Pathogenic	0.971
MEN1	O00255-1.4	S432W	Pathogenic	1.0
MEN1	O00255-1.4	S432Y	Pathogenic	0.997
MEN1	O00255-1.4	P433A	Neutral	0.13
MEN1	O00255-1.4	P433C	Neutral	0.031
MEN1	O00255-1.4	P433D	Neutral	0.142
MEN1	O00255-1.4	P433E	Neutral	0.339
MEN1	O00255-1.4	P433F	Pathogenic	0.729
MEN1	O00255-1.4	P433G	Pathogenic	0.519
MEN1	O00255-1.4	P433H	Neutral	0.234
MEN1	O00255-1.4	P433I	Pathogenic	0.533
MEN1	O00255-1.4	P433K	Pathogenic	0.863
MEN1	O00255-1.4	P433L	Neutral	0.491
MEN1	O00255-1.4	P433M	Neutral	0.298
MEN1	O00255-1.4	P433N	Neutral	0.163
MEN1	O00255-1.4	P433Q	Neutral	0.274
MEN1	O00255-1.4	P433R	Pathogenic	0.948
MEN1	O00255-1.4	P433S	Neutral	0.143
MEN1	O00255-1.4	P433T	Neutral	0.035
MEN1	O00255-1.4	P433V	Neutral	0.091
MEN1	O00255-1.4	P433W	Pathogenic	0.979
MEN1	O00255-1.4	P433Y	Pathogenic	0.509
MEN1	O00255-1.4	T434A	Pathogenic	0.967
MEN1	O00255-1.4	T434C	Pathogenic	0.958
MEN1	O00255-1.4	T434D	Pathogenic	0.962
MEN1	O00255-1.4	T434E	Pathogenic	0.983
MEN1	O00255-1.4	T434F	Pathogenic	0.999
MEN1	O00255-1.4	T434G	Pathogenic	0.995
MEN1	O00255-1.4	T434H	Pathogenic	0.972
MEN1	O00255-1.4	T434I	Pathogenic	0.998
MEN1	O00255-1.4	T434K	Pathogenic	0.999
MEN1	O00255-1.4	T434L	Pathogenic	0.998
MEN1	O00255-1.4	T434M	Pathogenic	0.995
MEN1	O00255-1.4	T434N	Pathogenic	0.951
MEN1	O00255-1.4	T434P	Pathogenic	0.916
MEN1	O00255-1.4	T434Q	Pathogenic	0.977
MEN1	O00255-1.4	T434R	Pathogenic	0.999
MEN1	O00255-1.4	T434S	Pathogenic	0.963
MEN1	O00255-1.4	T434V	Pathogenic	0.978
MEN1	O00255-1.4	T434W	Pathogenic	1.0
MEN1	O00255-1.4	T434Y	Pathogenic	0.998
MEN1	O00255-1.4	P435A	Pathogenic	0.948
MEN1	O00255-1.4	P435C	Pathogenic	0.798
MEN1	O00255-1.4	P435D	Pathogenic	0.953
MEN1	O00255-1.4	P435E	Pathogenic	0.984
MEN1	O00255-1.4	P435F	Pathogenic	0.997
MEN1	O00255-1.4	P435G	Pathogenic	0.993
MEN1	O00255-1.4	P435H	Pathogenic	0.974
MEN1	O00255-1.4	P435I	Pathogenic	0.993
MEN1	O00255-1.4	P435K	Pathogenic	0.999
MEN1	O00255-1.4	P435L	Pathogenic	0.992
MEN1	O00255-1.4	P435M	Pathogenic	0.981
MEN1	O00255-1.4	P435N	Pathogenic	0.96
MEN1	O00255-1.4	P435Q	Pathogenic	0.979
MEN1	O00255-1.4	P435R	Pathogenic	1.0
MEN1	O00255-1.4	P435S	Pathogenic	0.953
MEN1	O00255-1.4	P435T	Pathogenic	0.817
MEN1	O00255-1.4	P435V	Pathogenic	0.925
MEN1	O00255-1.4	P435W	Pathogenic	1.0
MEN1	O00255-1.4	P435Y	Pathogenic	0.992
MEN1	O00255-1.4	V436A	Pathogenic	0.976
MEN1	O00255-1.4	V436C	Pathogenic	0.777
MEN1	O00255-1.4	V436D	Pathogenic	0.979
MEN1	O00255-1.4	V436E	Pathogenic	0.943
MEN1	O00255-1.4	V436F	Pathogenic	0.932
MEN1	O00255-1.4	V436G	Pathogenic	0.997
MEN1	O00255-1.4	V436H	Pathogenic	0.909
MEN1	O00255-1.4	V436I	Pathogenic	0.829
MEN1	O00255-1.4	V436K	Pathogenic	0.995
MEN1	O00255-1.4	V436L	Pathogenic	0.822
MEN1	O00255-1.4	V436M	Pathogenic	0.683
MEN1	O00255-1.4	V436N	Pathogenic	0.96
MEN1	O00255-1.4	V436P	Pathogenic	0.808
MEN1	O00255-1.4	V436Q	Pathogenic	0.925
MEN1	O00255-1.4	V436R	Pathogenic	0.998
MEN1	O00255-1.4	V436S	Pathogenic	0.981
MEN1	O00255-1.4	V436T	Pathogenic	0.863
MEN1	O00255-1.4	V436W	Pathogenic	0.996
MEN1	O00255-1.4	V436Y	Pathogenic	0.928
MEN1	O00255-1.4	L437A	Pathogenic	0.996
MEN1	O00255-1.4	L437C	Pathogenic	0.956
MEN1	O00255-1.4	L437D	Pathogenic	0.997
MEN1	O00255-1.4	L437E	Pathogenic	0.984
MEN1	O00255-1.4	L437F	Neutral	0.493
MEN1	O00255-1.4	L437G	Pathogenic	1.0
MEN1	O00255-1.4	L437H	Pathogenic	0.898
MEN1	O00255-1.4	L437I	Neutral	0.279
MEN1	O00255-1.4	L437K	Pathogenic	0.987
MEN1	O00255-1.4	L437M	Neutral	0.413
MEN1	O00255-1.4	L437N	Pathogenic	0.993
MEN1	O00255-1.4	L437P	Pathogenic	0.965
MEN1	O00255-1.4	L437Q	Pathogenic	0.952
MEN1	O00255-1.4	L437R	Pathogenic	0.995
MEN1	O00255-1.4	L437S	Pathogenic	0.997
MEN1	O00255-1.4	L437T	Pathogenic	0.976
MEN1	O00255-1.4	L437V	Pathogenic	0.76
MEN1	O00255-1.4	L437W	Pathogenic	0.949
MEN1	O00255-1.4	L437Y	Pathogenic	0.823
MEN1	O00255-1.4	H438A	Pathogenic	0.999
MEN1	O00255-1.4	H438C	Pathogenic	0.999
MEN1	O00255-1.4	H438D	Pathogenic	0.998
MEN1	O00255-1.4	H438E	Pathogenic	0.991
MEN1	O00255-1.4	H438F	Pathogenic	0.999
MEN1	O00255-1.4	H438G	Pathogenic	1.0
MEN1	O00255-1.4	H438I	Pathogenic	0.998
MEN1	O00255-1.4	H438K	Pathogenic	0.997
MEN1	O00255-1.4	H438L	Pathogenic	0.997
MEN1	O00255-1.4	H438M	Pathogenic	0.994
MEN1	O00255-1.4	H438N	Pathogenic	0.996
MEN1	O00255-1.4	H438P	Pathogenic	0.997
MEN1	O00255-1.4	H438Q	Pathogenic	0.974
MEN1	O00255-1.4	H438R	Pathogenic	0.999
MEN1	O00255-1.4	H438S	Pathogenic	0.998
MEN1	O00255-1.4	H438T	Pathogenic	0.993
MEN1	O00255-1.4	H438V	Pathogenic	0.997
MEN1	O00255-1.4	H438W	Pathogenic	1.0
MEN1	O00255-1.4	H438Y	Pathogenic	0.997
MEN1	O00255-1.4	V439A	Pathogenic	0.822
MEN1	O00255-1.4	V439C	Neutral	0.285
MEN1	O00255-1.4	V439D	Pathogenic	0.841
MEN1	O00255-1.4	V439E	Pathogenic	0.656
MEN1	O00255-1.4	V439F	Pathogenic	0.61
MEN1	O00255-1.4	V439G	Pathogenic	0.974
MEN1	O00255-1.4	V439H	Pathogenic	0.533
MEN1	O00255-1.4	V439I	Neutral	0.357
MEN1	O00255-1.4	V439K	Pathogenic	0.959
MEN1	O00255-1.4	V439L	Neutral	0.346
MEN1	O00255-1.4	V439M	Neutral	0.198
MEN1	O00255-1.4	V439N	Pathogenic	0.735
MEN1	O00255-1.4	V439P	Neutral	0.325
MEN1	O00255-1.4	V439Q	Pathogenic	0.585
MEN1	O00255-1.4	V439R	Pathogenic	0.985
MEN1	O00255-1.4	V439S	Pathogenic	0.854
MEN1	O00255-1.4	V439T	Neutral	0.419
MEN1	O00255-1.4	V439W	Pathogenic	0.968
MEN1	O00255-1.4	V439Y	Pathogenic	0.595
MEN1	O00255-1.4	G440A	Pathogenic	0.727
MEN1	O00255-1.4	G440C	Pathogenic	0.975
MEN1	O00255-1.4	G440D	Pathogenic	0.973
MEN1	O00255-1.4	G440E	Pathogenic	0.992
MEN1	O00255-1.4	G440F	Pathogenic	1.0
MEN1	O00255-1.4	G440H	Pathogenic	0.99
MEN1	O00255-1.4	G440I	Pathogenic	1.0
MEN1	O00255-1.4	G440K	Pathogenic	0.999
MEN1	O00255-1.4	G440L	Pathogenic	1.0
MEN1	O00255-1.4	G440M	Pathogenic	0.999
MEN1	O00255-1.4	G440N	Pathogenic	0.974
MEN1	O00255-1.4	G440P	Pathogenic	0.97
MEN1	O00255-1.4	G440Q	Pathogenic	0.989
MEN1	O00255-1.4	G440R	Pathogenic	1.0
MEN1	O00255-1.4	G440S	Pathogenic	0.728
MEN1	O00255-1.4	G440T	Pathogenic	0.951
MEN1	O00255-1.4	G440V	Pathogenic	0.996
MEN1	O00255-1.4	G440W	Pathogenic	1.0
MEN1	O00255-1.4	G440Y	Pathogenic	1.0
MEN1	O00255-1.4	W441A	Pathogenic	1.0
MEN1	O00255-1.4	W441C	Pathogenic	1.0
MEN1	O00255-1.4	W441D	Pathogenic	1.0
MEN1	O00255-1.4	W441E	Pathogenic	1.0
MEN1	O00255-1.4	W441F	Pathogenic	0.998
MEN1	O00255-1.4	W441G	Pathogenic	1.0
MEN1	O00255-1.4	W441H	Pathogenic	1.0
MEN1	O00255-1.4	W441I	Pathogenic	0.999
MEN1	O00255-1.4	W441K	Pathogenic	1.0
MEN1	O00255-1.4	W441L	Pathogenic	1.0
MEN1	O00255-1.4	W441M	Pathogenic	1.0
MEN1	O00255-1.4	W441N	Pathogenic	1.0
MEN1	O00255-1.4	W441P	Pathogenic	1.0
MEN1	O00255-1.4	W441Q	Pathogenic	1.0
MEN1	O00255-1.4	W441R	Pathogenic	1.0
MEN1	O00255-1.4	W441S	Pathogenic	1.0
MEN1	O00255-1.4	W441T	Pathogenic	1.0
MEN1	O00255-1.4	W441V	Pathogenic	1.0
MEN1	O00255-1.4	W441Y	Pathogenic	0.999
MEN1	O00255-1.4	A442C	Pathogenic	0.916
MEN1	O00255-1.4	A442D	Pathogenic	0.972
MEN1	O00255-1.4	A442E	Pathogenic	0.99
MEN1	O00255-1.4	A442F	Pathogenic	0.999
MEN1	O00255-1.4	A442G	Pathogenic	0.858
MEN1	O00255-1.4	A442H	Pathogenic	0.984
MEN1	O00255-1.4	A442I	Pathogenic	0.999
MEN1	O00255-1.4	A442K	Pathogenic	0.999
MEN1	O00255-1.4	A442L	Pathogenic	0.998
MEN1	O00255-1.4	A442M	Pathogenic	0.997
MEN1	O00255-1.4	A442N	Pathogenic	0.974
MEN1	O00255-1.4	A442P	Pathogenic	0.911
MEN1	O00255-1.4	A442Q	Pathogenic	0.987
MEN1	O00255-1.4	A442R	Pathogenic	1.0
MEN1	O00255-1.4	A442S	Pathogenic	0.696
MEN1	O00255-1.4	A442T	Pathogenic	0.87
MEN1	O00255-1.4	A442V	Pathogenic	0.985
MEN1	O00255-1.4	A442W	Pathogenic	1.0
MEN1	O00255-1.4	A442Y	Pathogenic	0.999
MEN1	O00255-1.4	T443A	Neutral	0.332
MEN1	O00255-1.4	T443C	Neutral	0.276
MEN1	O00255-1.4	T443D	Neutral	0.3
MEN1	O00255-1.4	T443E	Neutral	0.496
MEN1	O00255-1.4	T443F	Pathogenic	0.953
MEN1	O00255-1.4	T443G	Pathogenic	0.764
MEN1	O00255-1.4	T443H	Neutral	0.37
MEN1	O00255-1.4	T443I	Pathogenic	0.897
MEN1	O00255-1.4	T443K	Pathogenic	0.924
MEN1	O00255-1.4	T443L	Pathogenic	0.88
MEN1	O00255-1.4	T443M	Pathogenic	0.774
MEN1	O00255-1.4	T443N	Neutral	0.248
MEN1	O00255-1.4	T443P	Neutral	0.156
MEN1	O00255-1.4	T443Q	Neutral	0.42
MEN1	O00255-1.4	T443R	Pathogenic	0.97
MEN1	O00255-1.4	T443S	Neutral	0.307
MEN1	O00255-1.4	T443V	Neutral	0.433
MEN1	O00255-1.4	T443W	Pathogenic	0.997
MEN1	O00255-1.4	T443Y	Pathogenic	0.893
MEN1	O00255-1.4	F444A	Pathogenic	0.983
MEN1	O00255-1.4	F444C	Pathogenic	0.825
MEN1	O00255-1.4	F444D	Pathogenic	0.983
MEN1	O00255-1.4	F444E	Pathogenic	0.926
MEN1	O00255-1.4	F444G	Pathogenic	0.998
MEN1	O00255-1.4	F444H	Pathogenic	0.618
MEN1	O00255-1.4	F444I	Neutral	0.063
MEN1	O00255-1.4	F444K	Pathogenic	0.76
MEN1	O00255-1.4	F444L	Neutral	0.071
MEN1	O00255-1.4	F444M	Neutral	0.14
MEN1	O00255-1.4	F444N	Pathogenic	0.969
MEN1	O00255-1.4	F444P	Pathogenic	0.858
MEN1	O00255-1.4	F444Q	Pathogenic	0.813
MEN1	O00255-1.4	F444R	Pathogenic	0.895
MEN1	O00255-1.4	F444S	Pathogenic	0.985
MEN1	O00255-1.4	F444T	Pathogenic	0.901
MEN1	O00255-1.4	F444V	Neutral	0.423
MEN1	O00255-1.4	F444W	Neutral	0.319
MEN1	O00255-1.4	F444Y	Neutral	0.127
MEN1	O00255-1.4	L445A	Pathogenic	0.995
MEN1	O00255-1.4	L445C	Pathogenic	0.938
MEN1	O00255-1.4	L445D	Pathogenic	0.995
MEN1	O00255-1.4	L445E	Pathogenic	0.977
MEN1	O00255-1.4	L445F	Neutral	0.406
MEN1	O00255-1.4	L445G	Pathogenic	0.999
MEN1	O00255-1.4	L445H	Pathogenic	0.862
MEN1	O00255-1.4	L445I	Neutral	0.214
MEN1	O00255-1.4	L445K	Pathogenic	0.981
MEN1	O00255-1.4	L445M	Neutral	0.331
MEN1	O00255-1.4	L445N	Pathogenic	0.991
MEN1	O00255-1.4	L445P	Pathogenic	0.951
MEN1	O00255-1.4	L445Q	Pathogenic	0.933
MEN1	O00255-1.4	L445R	Pathogenic	0.993
MEN1	O00255-1.4	L445S	Pathogenic	0.996
MEN1	O00255-1.4	L445T	Pathogenic	0.967
MEN1	O00255-1.4	L445V	Pathogenic	0.69
MEN1	O00255-1.4	L445W	Pathogenic	0.93
MEN1	O00255-1.4	L445Y	Pathogenic	0.766
MEN1	O00255-1.4	V446A	Pathogenic	0.983
MEN1	O00255-1.4	V446C	Pathogenic	0.829
MEN1	O00255-1.4	V446D	Pathogenic	0.985
MEN1	O00255-1.4	V446E	Pathogenic	0.959
MEN1	O00255-1.4	V446F	Pathogenic	0.95
MEN1	O00255-1.4	V446G	Pathogenic	0.998
MEN1	O00255-1.4	V446H	Pathogenic	0.933
MEN1	O00255-1.4	V446I	Pathogenic	0.871
MEN1	O00255-1.4	V446K	Pathogenic	0.997
MEN1	O00255-1.4	V446L	Pathogenic	0.866
MEN1	O00255-1.4	V446M	Pathogenic	0.751
MEN1	O00255-1.4	V446N	Pathogenic	0.971
MEN1	O00255-1.4	V446P	Pathogenic	0.854
MEN1	O00255-1.4	V446Q	Pathogenic	0.945
MEN1	O00255-1.4	V446R	Pathogenic	0.999
MEN1	O00255-1.4	V446S	Pathogenic	0.986
MEN1	O00255-1.4	V446T	Pathogenic	0.898
MEN1	O00255-1.4	V446W	Pathogenic	0.997
MEN1	O00255-1.4	V446Y	Pathogenic	0.947
MEN1	O00255-1.4	Q447A	Pathogenic	0.747
MEN1	O00255-1.4	Q447C	Pathogenic	0.706
MEN1	O00255-1.4	Q447D	Neutral	0.324
MEN1	O00255-1.4	Q447E	Neutral	0.082
MEN1	O00255-1.4	Q447F	Pathogenic	0.84
MEN1	O00255-1.4	Q447G	Pathogenic	0.887
MEN1	O00255-1.4	Q447H	Neutral	0.078
MEN1	O00255-1.4	Q447I	Pathogenic	0.703
MEN1	O00255-1.4	Q447K	Neutral	0.357
MEN1	O00255-1.4	Q447L	Pathogenic	0.654
MEN1	O00255-1.4	Q447M	Neutral	0.439
MEN1	O00255-1.4	Q447N	Neutral	0.2
MEN1	O00255-1.4	Q447P	Pathogenic	0.507
MEN1	O00255-1.4	Q447R	Pathogenic	0.6
MEN1	O00255-1.4	Q447S	Pathogenic	0.503
MEN1	O00255-1.4	Q447T	Neutral	0.28
MEN1	O00255-1.4	Q447V	Neutral	0.445
MEN1	O00255-1.4	Q447W	Pathogenic	0.988
MEN1	O00255-1.4	Q447Y	Pathogenic	0.656
MEN1	O00255-1.4	S448A	Neutral	0.202
MEN1	O00255-1.4	S448C	Pathogenic	0.589
MEN1	O00255-1.4	S448D	Pathogenic	0.553
MEN1	O00255-1.4	S448E	Pathogenic	0.793
MEN1	O00255-1.4	S448F	Pathogenic	0.995
MEN1	O00255-1.4	S448G	Neutral	0.402
MEN1	O00255-1.4	S448H	Pathogenic	0.798
MEN1	O00255-1.4	S448I	Pathogenic	0.99
MEN1	O00255-1.4	S448K	Pathogenic	0.979
MEN1	O00255-1.4	S448L	Pathogenic	0.988
MEN1	O00255-1.4	S448M	Pathogenic	0.974
MEN1	O00255-1.4	S448N	Pathogenic	0.562
MEN1	O00255-1.4	S448P	Pathogenic	0.558
MEN1	O00255-1.4	S448Q	Pathogenic	0.738
MEN1	O00255-1.4	S448R	Pathogenic	0.993
MEN1	O00255-1.4	S448T	Neutral	0.398
MEN1	O00255-1.4	S448V	Pathogenic	0.902
MEN1	O00255-1.4	S448W	Pathogenic	1.0
MEN1	O00255-1.4	S448Y	Pathogenic	0.989
MEN1	O00255-1.4	L449A	Pathogenic	0.941
MEN1	O00255-1.4	L449C	Pathogenic	0.563
MEN1	O00255-1.4	L449D	Pathogenic	0.948
MEN1	O00255-1.4	L449E	Pathogenic	0.783
MEN1	O00255-1.4	L449F	Neutral	0.055
MEN1	O00255-1.4	L449G	Pathogenic	0.992
MEN1	O00255-1.4	L449H	Neutral	0.346
MEN1	O00255-1.4	L449I	Neutral	0.023
MEN1	O00255-1.4	L449K	Pathogenic	0.817
MEN1	O00255-1.4	L449M	Neutral	0.04
MEN1	O00255-1.4	L449N	Pathogenic	0.9
MEN1	O00255-1.4	L449P	Pathogenic	0.623
MEN1	O00255-1.4	L449Q	Pathogenic	0.543
MEN1	O00255-1.4	L449R	Pathogenic	0.923
MEN1	O00255-1.4	L449S	Pathogenic	0.95
MEN1	O00255-1.4	L449T	Pathogenic	0.713
MEN1	O00255-1.4	L449V	Neutral	0.159
MEN1	O00255-1.4	L449W	Pathogenic	0.529
MEN1	O00255-1.4	L449Y	Neutral	0.218
MEN1	O00255-1.4	G450A	Neutral	0.061
MEN1	O00255-1.4	G450C	Neutral	0.488
MEN1	O00255-1.4	G450D	Neutral	0.465
MEN1	O00255-1.4	G450E	Pathogenic	0.741
MEN1	O00255-1.4	G450F	Pathogenic	0.993
MEN1	O00255-1.4	G450H	Pathogenic	0.711
MEN1	O00255-1.4	G450I	Pathogenic	0.985
MEN1	O00255-1.4	G450K	Pathogenic	0.972
MEN1	O00255-1.4	G450L	Pathogenic	0.982
MEN1	O00255-1.4	G450M	Pathogenic	0.961
MEN1	O00255-1.4	G450N	Neutral	0.475
MEN1	O00255-1.4	G450P	Neutral	0.441
MEN1	O00255-1.4	G450Q	Pathogenic	0.678
MEN1	O00255-1.4	G450R	Pathogenic	0.99
MEN1	O00255-1.4	G450S	Neutral	0.061
MEN1	O00255-1.4	G450T	Neutral	0.318
MEN1	O00255-1.4	G450V	Pathogenic	0.852
MEN1	O00255-1.4	G450W	Pathogenic	1.0
MEN1	O00255-1.4	G450Y	Pathogenic	0.982
MEN1	O00255-1.4	R451A	Pathogenic	0.997
MEN1	O00255-1.4	R451C	Pathogenic	0.996
MEN1	O00255-1.4	R451D	Pathogenic	0.904
MEN1	O00255-1.4	R451E	Pathogenic	0.73
MEN1	O00255-1.4	R451F	Pathogenic	0.96
MEN1	O00255-1.4	R451G	Pathogenic	0.999
MEN1	O00255-1.4	R451H	Pathogenic	0.828
MEN1	O00255-1.4	R451I	Pathogenic	0.982
MEN1	O00255-1.4	R451K	Neutral	0.162
MEN1	O00255-1.4	R451L	Pathogenic	0.978
MEN1	O00255-1.4	R451M	Pathogenic	0.951
MEN1	O00255-1.4	R451N	Pathogenic	0.883
MEN1	O00255-1.4	R451P	Pathogenic	0.991
MEN1	O00255-1.4	R451Q	Pathogenic	0.775
MEN1	O00255-1.4	R451S	Pathogenic	0.991
MEN1	O00255-1.4	R451T	Pathogenic	0.976
MEN1	O00255-1.4	R451V	Pathogenic	0.989
MEN1	O00255-1.4	R451W	Pathogenic	0.983
MEN1	O00255-1.4	R451Y	Pathogenic	0.788
MEN1	O00255-1.4	F452A	Pathogenic	1.0
MEN1	O00255-1.4	F452C	Pathogenic	0.999
MEN1	O00255-1.4	F452D	Pathogenic	1.0
MEN1	O00255-1.4	F452E	Pathogenic	1.0
MEN1	O00255-1.4	F452G	Pathogenic	1.0
MEN1	O00255-1.4	F452H	Pathogenic	0.997
MEN1	O00255-1.4	F452I	Pathogenic	0.941
MEN1	O00255-1.4	F452K	Pathogenic	0.999
MEN1	O00255-1.4	F452L	Pathogenic	0.948
MEN1	O00255-1.4	F452M	Pathogenic	0.975
MEN1	O00255-1.4	F452N	Pathogenic	1.0
MEN1	O00255-1.4	F452P	Pathogenic	0.999
MEN1	O00255-1.4	F452Q	Pathogenic	0.999
MEN1	O00255-1.4	F452R	Pathogenic	1.0
MEN1	O00255-1.4	F452S	Pathogenic	1.0
MEN1	O00255-1.4	F452T	Pathogenic	1.0
MEN1	O00255-1.4	F452V	Pathogenic	0.994
MEN1	O00255-1.4	F452W	Pathogenic	0.991
MEN1	O00255-1.4	F452Y	Pathogenic	0.972
MEN1	O00255-1.4	E453A	Pathogenic	0.509
MEN1	O00255-1.4	E453C	Neutral	0.473
MEN1	O00255-1.4	E453D	Neutral	0.037
MEN1	O00255-1.4	E453F	Pathogenic	0.796
MEN1	O00255-1.4	E453G	Pathogenic	0.734
MEN1	O00255-1.4	E453H	Neutral	0.059
MEN1	O00255-1.4	E453I	Pathogenic	0.638
MEN1	O00255-1.4	E453K	Neutral	0.096
MEN1	O00255-1.4	E453L	Pathogenic	0.598
MEN1	O00255-1.4	E453M	Neutral	0.396
MEN1	O00255-1.4	E453N	Neutral	0.025
MEN1	O00255-1.4	E453P	Neutral	0.266
MEN1	O00255-1.4	E453Q	Neutral	0.023
MEN1	O00255-1.4	E453R	Neutral	0.234
MEN1	O00255-1.4	E453S	Neutral	0.263
MEN1	O00255-1.4	E453T	Neutral	0.12
MEN1	O00255-1.4	E453V	Neutral	0.22
MEN1	O00255-1.4	E453W	Pathogenic	0.985
MEN1	O00255-1.4	E453Y	Pathogenic	0.601
MEN1	O00255-1.4	G454A	Neutral	0.023
MEN1	O00255-1.4	G454C	Neutral	0.258
MEN1	O00255-1.4	G454D	Neutral	0.241
MEN1	O00255-1.4	G454E	Pathogenic	0.511
MEN1	O00255-1.4	G454F	Pathogenic	0.98
MEN1	O00255-1.4	G454H	Neutral	0.474
MEN1	O00255-1.4	G454I	Pathogenic	0.96
MEN1	O00255-1.4	G454K	Pathogenic	0.928
MEN1	O00255-1.4	G454L	Pathogenic	0.953
MEN1	O00255-1.4	G454M	Pathogenic	0.899
MEN1	O00255-1.4	G454N	Neutral	0.249
MEN1	O00255-1.4	G454P	Neutral	0.224
MEN1	O00255-1.4	G454Q	Neutral	0.435
MEN1	O00255-1.4	G454R	Pathogenic	0.972
MEN1	O00255-1.4	G454S	Neutral	0.023
MEN1	O00255-1.4	G454T	Neutral	0.146
MEN1	O00255-1.4	G454V	Pathogenic	0.678
MEN1	O00255-1.4	G454W	Pathogenic	0.999
MEN1	O00255-1.4	G454Y	Pathogenic	0.953
MEN1	O00255-1.4	Q455A	Pathogenic	0.62
MEN1	O00255-1.4	Q455C	Pathogenic	0.571
MEN1	O00255-1.4	Q455D	Neutral	0.209
MEN1	O00255-1.4	Q455E	Neutral	0.047
MEN1	O00255-1.4	Q455F	Pathogenic	0.744
MEN1	O00255-1.4	Q455G	Pathogenic	0.813
MEN1	O00255-1.4	Q455H	Neutral	0.044
MEN1	O00255-1.4	Q455I	Pathogenic	0.567
MEN1	O00255-1.4	Q455K	Neutral	0.235
MEN1	O00255-1.4	Q455L	Pathogenic	0.511
MEN1	O00255-1.4	Q455M	Neutral	0.302
MEN1	O00255-1.4	Q455N	Neutral	0.122
MEN1	O00255-1.4	Q455P	Neutral	0.363
MEN1	O00255-1.4	Q455R	Neutral	0.454
MEN1	O00255-1.4	Q455S	Neutral	0.359
MEN1	O00255-1.4	Q455T	Neutral	0.177
MEN1	O00255-1.4	Q455V	Neutral	0.307
MEN1	O00255-1.4	Q455W	Pathogenic	0.979
MEN1	O00255-1.4	Q455Y	Pathogenic	0.513
MEN1	O00255-1.4	V456A	Pathogenic	0.743
MEN1	O00255-1.4	V456C	Neutral	0.2
MEN1	O00255-1.4	V456D	Pathogenic	0.769
MEN1	O00255-1.4	V456E	Pathogenic	0.545
MEN1	O00255-1.4	V456F	Neutral	0.495
MEN1	O00255-1.4	V456G	Pathogenic	0.959
MEN1	O00255-1.4	V456H	Neutral	0.416
MEN1	O00255-1.4	V456I	Neutral	0.258
MEN1	O00255-1.4	V456K	Pathogenic	0.937
MEN1	O00255-1.4	V456L	Neutral	0.249
MEN1	O00255-1.4	V456M	Neutral	0.134
MEN1	O00255-1.4	V456N	Pathogenic	0.635
MEN1	O00255-1.4	V456P	Neutral	0.232
MEN1	O00255-1.4	V456Q	Neutral	0.469
MEN1	O00255-1.4	V456R	Pathogenic	0.977
MEN1	O00255-1.4	V456S	Pathogenic	0.785
MEN1	O00255-1.4	V456T	Neutral	0.311
MEN1	O00255-1.4	V456W	Pathogenic	0.95
MEN1	O00255-1.4	V456Y	Neutral	0.479
MEN1	O00255-1.4	R457A	Pathogenic	1.0
MEN1	O00255-1.4	R457C	Pathogenic	1.0
MEN1	O00255-1.4	R457D	Pathogenic	0.997
MEN1	O00255-1.4	R457E	Pathogenic	0.988
MEN1	O00255-1.4	R457F	Pathogenic	0.999
MEN1	O00255-1.4	R457G	Pathogenic	1.0
MEN1	O00255-1.4	R457H	Pathogenic	0.993
MEN1	O00255-1.4	R457I	Pathogenic	0.999
MEN1	O00255-1.4	R457K	Pathogenic	0.856
MEN1	O00255-1.4	R457L	Pathogenic	0.999
MEN1	O00255-1.4	R457M	Pathogenic	0.998
MEN1	O00255-1.4	R457N	Pathogenic	0.996
MEN1	O00255-1.4	R457P	Pathogenic	1.0
MEN1	O00255-1.4	R457Q	Pathogenic	0.991
MEN1	O00255-1.4	R457S	Pathogenic	1.0
MEN1	O00255-1.4	R457T	Pathogenic	0.999
MEN1	O00255-1.4	R457V	Pathogenic	1.0
MEN1	O00255-1.4	R457W	Pathogenic	0.999
MEN1	O00255-1.4	R457Y	Pathogenic	0.991
MEN1	O00255-1.4	Q458A	Neutral	0.447
MEN1	O00255-1.4	Q458C	Neutral	0.397
MEN1	O00255-1.4	Q458D	Neutral	0.116
MEN1	O00255-1.4	Q458E	Neutral	0.024
MEN1	O00255-1.4	Q458F	Pathogenic	0.591
MEN1	O00255-1.4	Q458G	Pathogenic	0.683
MEN1	O00255-1.4	Q458H	Neutral	0.023
MEN1	O00255-1.4	Q458I	Neutral	0.394
MEN1	O00255-1.4	Q458K	Neutral	0.132
MEN1	O00255-1.4	Q458L	Neutral	0.341
MEN1	O00255-1.4	Q458M	Neutral	0.177
MEN1	O00255-1.4	Q458N	Neutral	0.064
MEN1	O00255-1.4	Q458P	Neutral	0.22
MEN1	O00255-1.4	Q458R	Neutral	0.291
MEN1	O00255-1.4	Q458S	Neutral	0.217
MEN1	O00255-1.4	Q458T	Neutral	0.096
MEN1	O00255-1.4	Q458V	Neutral	0.18
MEN1	O00255-1.4	Q458W	Pathogenic	0.959
MEN1	O00255-1.4	Q458Y	Neutral	0.343
MEN1	O00255-1.4	K459A	Pathogenic	0.93
MEN1	O00255-1.4	K459C	Pathogenic	0.915
MEN1	O00255-1.4	K459D	Neutral	0.278
MEN1	O00255-1.4	K459E	Neutral	0.099
MEN1	O00255-1.4	K459F	Pathogenic	0.507
MEN1	O00255-1.4	K459G	Pathogenic	0.972
MEN1	O00255-1.4	K459H	Neutral	0.181
MEN1	O00255-1.4	K459I	Pathogenic	0.706
MEN1	O00255-1.4	K459L	Pathogenic	0.657
MEN1	O00255-1.4	K459M	Neutral	0.457
MEN1	O00255-1.4	K459N	Neutral	0.247
MEN1	O00255-1.4	K459P	Pathogenic	0.823
MEN1	O00255-1.4	K459Q	Neutral	0.13
MEN1	O00255-1.4	K459R	Neutral	0.022
MEN1	O00255-1.4	K459S	Pathogenic	0.82
MEN1	O00255-1.4	K459T	Pathogenic	0.637
MEN1	O00255-1.4	K459V	Pathogenic	0.783
MEN1	O00255-1.4	K459W	Pathogenic	0.946
MEN1	O00255-1.4	K459Y	Neutral	0.284
MEN1	O00255-1.4	V460A	Pathogenic	0.777
MEN1	O00255-1.4	V460C	Neutral	0.231
MEN1	O00255-1.4	V460D	Pathogenic	0.8
MEN1	O00255-1.4	V460E	Pathogenic	0.591
MEN1	O00255-1.4	V460F	Pathogenic	0.542
MEN1	O00255-1.4	V460G	Pathogenic	0.966
MEN1	O00255-1.4	V460H	Neutral	0.463
MEN1	O00255-1.4	V460I	Neutral	0.295
MEN1	O00255-1.4	V460K	Pathogenic	0.947
MEN1	O00255-1.4	V460L	Neutral	0.285
MEN1	O00255-1.4	V460M	Neutral	0.157
MEN1	O00255-1.4	V460N	Pathogenic	0.677
MEN1	O00255-1.4	V460P	Neutral	0.267
MEN1	O00255-1.4	V460Q	Pathogenic	0.515
MEN1	O00255-1.4	V460R	Pathogenic	0.981
MEN1	O00255-1.4	V460S	Pathogenic	0.815
MEN1	O00255-1.4	V460T	Neutral	0.353
MEN1	O00255-1.4	V460W	Pathogenic	0.958
MEN1	O00255-1.4	V460Y	Pathogenic	0.526
MEN1	O00255-1.4	R461A	Neutral	0.384
MEN1	O00255-1.4	R461C	Neutral	0.337
MEN1	O00255-1.4	R461D	Neutral	0.019
MEN1	O00255-1.4	R461E	Neutral	0.005
MEN1	O00255-1.4	R461F	Neutral	0.046
MEN1	O00255-1.4	R461G	Pathogenic	0.624
MEN1	O00255-1.4	R461H	Neutral	0.01
MEN1	O00255-1.4	R461I	Neutral	0.101
MEN1	O00255-1.4	R461K	Neutral	0.0
MEN1	O00255-1.4	R461L	Neutral	0.082
MEN1	O00255-1.4	R461M	Neutral	0.038
MEN1	O00255-1.4	R461N	Neutral	0.015
MEN1	O00255-1.4	R461P	Neutral	0.188
MEN1	O00255-1.4	R461Q	Neutral	0.007
MEN1	O00255-1.4	R461S	Neutral	0.185
MEN1	O00255-1.4	R461T	Neutral	0.076
MEN1	O00255-1.4	R461V	Neutral	0.152
MEN1	O00255-1.4	R461W	Neutral	0.106
MEN1	O00255-1.4	R461Y	Neutral	0.008
MEN1	O00255-1.4	I462A	Pathogenic	0.991
MEN1	O00255-1.4	I462C	Pathogenic	0.897
MEN1	O00255-1.4	I462D	Pathogenic	0.991
MEN1	O00255-1.4	I462E	Pathogenic	0.96
MEN1	O00255-1.4	I462F	Neutral	0.227
MEN1	O00255-1.4	I462G	Pathogenic	0.999
MEN1	O00255-1.4	I462H	Pathogenic	0.781
MEN1	O00255-1.4	I462K	Pathogenic	0.97
MEN1	O00255-1.4	I462L	Neutral	0.117
MEN1	O00255-1.4	I462M	Neutral	0.231
MEN1	O00255-1.4	I462N	Pathogenic	0.984
MEN1	O00255-1.4	I462P	Pathogenic	0.918
MEN1	O00255-1.4	I462Q	Pathogenic	0.895
MEN1	O00255-1.4	I462R	Pathogenic	0.989
MEN1	O00255-1.4	I462S	Pathogenic	0.992
MEN1	O00255-1.4	I462T	Pathogenic	0.943
MEN1	O00255-1.4	I462V	Pathogenic	0.53
MEN1	O00255-1.4	I462W	Pathogenic	0.852
MEN1	O00255-1.4	I462Y	Pathogenic	0.652
MEN1	O00255-1.4	V463A	Neutral	0.04
MEN1	O00255-1.4	V463C	Neutral	0.004
MEN1	O00255-1.4	V463D	Neutral	0.045
MEN1	O00255-1.4	V463E	Neutral	0.017
MEN1	O00255-1.4	V463F	Neutral	0.014
MEN1	O00255-1.4	V463G	Neutral	0.252
MEN1	O00255-1.4	V463H	Neutral	0.01
MEN1	O00255-1.4	V463I	Neutral	0.005
MEN1	O00255-1.4	V463K	Neutral	0.174
MEN1	O00255-1.4	V463L	Neutral	0.005
MEN1	O00255-1.4	V463M	Neutral	0.002
MEN1	O00255-1.4	V463N	Neutral	0.024
MEN1	O00255-1.4	V463P	Neutral	0.004
MEN1	O00255-1.4	V463Q	Neutral	0.012
MEN1	O00255-1.4	V463R	Neutral	0.377
MEN1	O00255-1.4	V463S	Neutral	0.05
MEN1	O00255-1.4	V463T	Neutral	0.006
MEN1	O00255-1.4	V463W	Neutral	0.213
MEN1	O00255-1.4	V463Y	Neutral	0.013
MEN1	O00255-1.4	S464A	Neutral	0.002
MEN1	O00255-1.4	S464C	Neutral	0.012
MEN1	O00255-1.4	S464D	Neutral	0.011
MEN1	O00255-1.4	S464E	Neutral	0.032
MEN1	O00255-1.4	S464F	Pathogenic	0.653
MEN1	O00255-1.4	S464G	Neutral	0.006
MEN1	O00255-1.4	S464H	Neutral	0.033
MEN1	O00255-1.4	S464I	Neutral	0.459
MEN1	O00255-1.4	S464K	Neutral	0.289
MEN1	O00255-1.4	S464L	Neutral	0.418
MEN1	O00255-1.4	S464M	Neutral	0.24
MEN1	O00255-1.4	S464N	Neutral	0.011
MEN1	O00255-1.4	S464P	Neutral	0.011
MEN1	O00255-1.4	S464Q	Neutral	0.024
MEN1	O00255-1.4	S464R	Pathogenic	0.538
MEN1	O00255-1.4	S464T	Neutral	0.006
MEN1	O00255-1.4	S464V	Neutral	0.073
MEN1	O00255-1.4	S464W	Pathogenic	0.972
MEN1	O00255-1.4	S464Y	Neutral	0.435
MEN1	O00255-1.4	R465A	Pathogenic	0.712
MEN1	O00255-1.4	R465C	Pathogenic	0.668
MEN1	O00255-1.4	R465D	Neutral	0.071
MEN1	O00255-1.4	R465E	Neutral	0.021
MEN1	O00255-1.4	R465F	Neutral	0.161
MEN1	O00255-1.4	R465G	Pathogenic	0.868
MEN1	O00255-1.4	R465H	Neutral	0.037
MEN1	O00255-1.4	R465I	Neutral	0.309
MEN1	O00255-1.4	R465K	Neutral	0.002
MEN1	O00255-1.4	R465L	Neutral	0.263
MEN1	O00255-1.4	R465M	Neutral	0.136
MEN1	O00255-1.4	R465N	Neutral	0.058
MEN1	O00255-1.4	R465P	Neutral	0.479
MEN1	O00255-1.4	R465Q	Neutral	0.027
MEN1	O00255-1.4	R465S	Neutral	0.475
MEN1	O00255-1.4	R465T	Neutral	0.246
MEN1	O00255-1.4	R465V	Neutral	0.416
MEN1	O00255-1.4	R465W	Neutral	0.32
MEN1	O00255-1.4	R465Y	Neutral	0.029
MEN1	O00255-1.4	E466A	Neutral	0.315
MEN1	O00255-1.4	E466C	Neutral	0.284
MEN1	O00255-1.4	E466D	Neutral	0.017
MEN1	O00255-1.4	E466F	Pathogenic	0.634
MEN1	O00255-1.4	E466G	Pathogenic	0.55
MEN1	O00255-1.4	E466H	Neutral	0.027
MEN1	O00255-1.4	E466I	Neutral	0.438
MEN1	O00255-1.4	E466K	Neutral	0.045
MEN1	O00255-1.4	E466L	Neutral	0.398
MEN1	O00255-1.4	E466M	Neutral	0.225
MEN1	O00255-1.4	E466N	Neutral	0.011
MEN1	O00255-1.4	E466P	Neutral	0.138
MEN1	O00255-1.4	E466Q	Neutral	0.01
MEN1	O00255-1.4	E466R	Neutral	0.119
MEN1	O00255-1.4	E466S	Neutral	0.136
MEN1	O00255-1.4	E466T	Neutral	0.057
MEN1	O00255-1.4	E466V	Neutral	0.111
MEN1	O00255-1.4	E466W	Pathogenic	0.967
MEN1	O00255-1.4	E466Y	Neutral	0.4
MEN1	O00255-1.4	A467C	Neutral	0.001
MEN1	O00255-1.4	A467D	Neutral	0.004
MEN1	O00255-1.4	A467E	Neutral	0.011
MEN1	O00255-1.4	A467F	Neutral	0.166
MEN1	O00255-1.4	A467G	Neutral	0.001
MEN1	O00255-1.4	A467H	Neutral	0.007
MEN1	O00255-1.4	A467I	Neutral	0.078
MEN1	O00255-1.4	A467K	Neutral	0.122
MEN1	O00255-1.4	A467L	Neutral	0.067
MEN1	O00255-1.4	A467M	Neutral	0.032
MEN1	O00255-1.4	A467N	Neutral	0.004
MEN1	O00255-1.4	A467P	Neutral	0.001
MEN1	O00255-1.4	A467Q	Neutral	0.008
MEN1	O00255-1.4	A467R	Neutral	0.273
MEN1	O00255-1.4	A467S	Neutral	0.0
MEN1	O00255-1.4	A467T	Neutral	0.001
MEN1	O00255-1.4	A467V	Neutral	0.007
MEN1	O00255-1.4	A467W	Pathogenic	0.783
MEN1	O00255-1.4	A467Y	Neutral	0.075
MEN1	O00255-1.4	E468A	Neutral	0.427
MEN1	O00255-1.4	E468C	Neutral	0.392
MEN1	O00255-1.4	E468D	Neutral	0.027
MEN1	O00255-1.4	E468F	Pathogenic	0.737
MEN1	O00255-1.4	E468G	Pathogenic	0.665
MEN1	O00255-1.4	E468H	Neutral	0.043
MEN1	O00255-1.4	E468I	Pathogenic	0.558
MEN1	O00255-1.4	E468K	Neutral	0.071
MEN1	O00255-1.4	E468L	Pathogenic	0.517
MEN1	O00255-1.4	E468M	Neutral	0.32
MEN1	O00255-1.4	E468N	Neutral	0.018
MEN1	O00255-1.4	E468P	Neutral	0.206
MEN1	O00255-1.4	E468Q	Neutral	0.016
MEN1	O00255-1.4	E468R	Neutral	0.179
MEN1	O00255-1.4	E468S	Neutral	0.204
MEN1	O00255-1.4	E468T	Neutral	0.089
MEN1	O00255-1.4	E468V	Neutral	0.168
MEN1	O00255-1.4	E468W	Pathogenic	0.98
MEN1	O00255-1.4	E468Y	Pathogenic	0.519
MEN1	O00255-1.4	A469C	Neutral	0.003
MEN1	O00255-1.4	A469D	Neutral	0.009
MEN1	O00255-1.4	A469E	Neutral	0.027
MEN1	O00255-1.4	A469F	Neutral	0.327
MEN1	O00255-1.4	A469G	Neutral	0.002
MEN1	O00255-1.4	A469H	Neutral	0.016
MEN1	O00255-1.4	A469I	Neutral	0.171
MEN1	O00255-1.4	A469K	Neutral	0.254
MEN1	O00255-1.4	A469L	Neutral	0.148
MEN1	O00255-1.4	A469M	Neutral	0.075
MEN1	O00255-1.4	A469N	Neutral	0.01
MEN1	O00255-1.4	A469P	Neutral	0.003
MEN1	O00255-1.4	A469Q	Neutral	0.02
MEN1	O00255-1.4	A469R	Neutral	0.479
MEN1	O00255-1.4	A469S	Neutral	0.001
MEN1	O00255-1.4	A469T	Neutral	0.002
MEN1	O00255-1.4	A469V	Neutral	0.018
MEN1	O00255-1.4	A469W	Pathogenic	0.898
MEN1	O00255-1.4	A469Y	Neutral	0.166
MEN1	O00255-1.4	A470C	Neutral	0.002
MEN1	O00255-1.4	A470D	Neutral	0.006
MEN1	O00255-1.4	A470E	Neutral	0.018
MEN1	O00255-1.4	A470F	Neutral	0.245
MEN1	O00255-1.4	A470G	Neutral	0.001
MEN1	O00255-1.4	A470H	Neutral	0.011
MEN1	O00255-1.4	A470I	Neutral	0.121
MEN1	O00255-1.4	A470K	Neutral	0.185
MEN1	O00255-1.4	A470L	Neutral	0.104
MEN1	O00255-1.4	A470M	Neutral	0.052
MEN1	O00255-1.4	A470N	Neutral	0.007
MEN1	O00255-1.4	A470P	Neutral	0.002
MEN1	O00255-1.4	A470Q	Neutral	0.013
MEN1	O00255-1.4	A470R	Neutral	0.381
MEN1	O00255-1.4	A470S	Neutral	0.0
MEN1	O00255-1.4	A470T	Neutral	0.001
MEN1	O00255-1.4	A470V	Neutral	0.012
MEN1	O00255-1.4	A470W	Pathogenic	0.855
MEN1	O00255-1.4	A470Y	Neutral	0.117
MEN1	O00255-1.4	E471A	Neutral	0.201
MEN1	O00255-1.4	E471C	Neutral	0.179
MEN1	O00255-1.4	E471D	Neutral	0.009
MEN1	O00255-1.4	E471F	Neutral	0.487
MEN1	O00255-1.4	E471G	Neutral	0.401
MEN1	O00255-1.4	E471H	Neutral	0.015
MEN1	O00255-1.4	E471I	Neutral	0.3
MEN1	O00255-1.4	E471K	Neutral	0.025
MEN1	O00255-1.4	E471L	Neutral	0.266
MEN1	O00255-1.4	E471M	Neutral	0.137
MEN1	O00255-1.4	E471N	Neutral	0.006
MEN1	O00255-1.4	E471P	Neutral	0.081
MEN1	O00255-1.4	E471Q	Neutral	0.006
MEN1	O00255-1.4	E471R	Neutral	0.069
MEN1	O00255-1.4	E471S	Neutral	0.08
MEN1	O00255-1.4	E471T	Neutral	0.032
MEN1	O00255-1.4	E471V	Neutral	0.064
MEN1	O00255-1.4	E471W	Pathogenic	0.942
MEN1	O00255-1.4	E471Y	Neutral	0.267
MEN1	O00255-1.4	A472C	Neutral	0.003
MEN1	O00255-1.4	A472D	Neutral	0.01
MEN1	O00255-1.4	A472E	Neutral	0.028
MEN1	O00255-1.4	A472F	Neutral	0.333
MEN1	O00255-1.4	A472G	Neutral	0.002
MEN1	O00255-1.4	A472H	Neutral	0.017
MEN1	O00255-1.4	A472I	Neutral	0.175
MEN1	O00255-1.4	A472K	Neutral	0.259
MEN1	O00255-1.4	A472L	Neutral	0.152
MEN1	O00255-1.4	A472M	Neutral	0.077
MEN1	O00255-1.4	A472N	Neutral	0.011
MEN1	O00255-1.4	A472P	Neutral	0.003
MEN1	O00255-1.4	A472Q	Neutral	0.02
MEN1	O00255-1.4	A472R	Neutral	0.486
MEN1	O00255-1.4	A472S	Neutral	0.001
MEN1	O00255-1.4	A472T	Neutral	0.002
MEN1	O00255-1.4	A472V	Neutral	0.018
MEN1	O00255-1.4	A472W	Pathogenic	0.901
MEN1	O00255-1.4	A472Y	Neutral	0.169
MEN1	O00255-1.4	E473A	Neutral	0.199
MEN1	O00255-1.4	E473C	Neutral	0.177
MEN1	O00255-1.4	E473D	Neutral	0.009
MEN1	O00255-1.4	E473F	Neutral	0.484
MEN1	O00255-1.4	E473G	Neutral	0.399
MEN1	O00255-1.4	E473H	Neutral	0.015
MEN1	O00255-1.4	E473I	Neutral	0.297
MEN1	O00255-1.4	E473K	Neutral	0.025
MEN1	O00255-1.4	E473L	Neutral	0.264
MEN1	O00255-1.4	E473M	Neutral	0.136
MEN1	O00255-1.4	E473N	Neutral	0.006
MEN1	O00255-1.4	E473P	Neutral	0.08
MEN1	O00255-1.4	E473Q	Neutral	0.006
MEN1	O00255-1.4	E473R	Neutral	0.068
MEN1	O00255-1.4	E473S	Neutral	0.079
MEN1	O00255-1.4	E473T	Neutral	0.032
MEN1	O00255-1.4	E473V	Neutral	0.063
MEN1	O00255-1.4	E473W	Pathogenic	0.941
MEN1	O00255-1.4	E473Y	Neutral	0.265
MEN1	O00255-1.4	E474A	Neutral	0.204
MEN1	O00255-1.4	E474C	Neutral	0.182
MEN1	O00255-1.4	E474D	Neutral	0.009
MEN1	O00255-1.4	E474F	Neutral	0.492
MEN1	O00255-1.4	E474G	Neutral	0.406
MEN1	O00255-1.4	E474H	Neutral	0.015
MEN1	O00255-1.4	E474I	Neutral	0.303
MEN1	O00255-1.4	E474K	Neutral	0.026
MEN1	O00255-1.4	E474L	Neutral	0.269
MEN1	O00255-1.4	E474M	Neutral	0.14
MEN1	O00255-1.4	E474N	Neutral	0.006
MEN1	O00255-1.4	E474P	Neutral	0.082
MEN1	O00255-1.4	E474Q	Neutral	0.006
MEN1	O00255-1.4	E474R	Neutral	0.07
MEN1	O00255-1.4	E474S	Neutral	0.081
MEN1	O00255-1.4	E474T	Neutral	0.033
MEN1	O00255-1.4	E474V	Neutral	0.065
MEN1	O00255-1.4	E474W	Pathogenic	0.943
MEN1	O00255-1.4	E474Y	Neutral	0.271
MEN1	O00255-1.4	P475A	Neutral	0.002
MEN1	O00255-1.4	P475C	Neutral	0.0
MEN1	O00255-1.4	P475D	Neutral	0.002
MEN1	O00255-1.4	P475E	Neutral	0.006
MEN1	O00255-1.4	P475F	Neutral	0.029
MEN1	O00255-1.4	P475G	Neutral	0.012
MEN1	O00255-1.4	P475H	Neutral	0.003
MEN1	O00255-1.4	P475I	Neutral	0.013
MEN1	O00255-1.4	P475K	Neutral	0.067
MEN1	O00255-1.4	P475L	Neutral	0.011
MEN1	O00255-1.4	P475M	Neutral	0.005
MEN1	O00255-1.4	P475N	Neutral	0.002
MEN1	O00255-1.4	P475Q	Neutral	0.004
MEN1	O00255-1.4	P475R	Neutral	0.17
MEN1	O00255-1.4	P475S	Neutral	0.002
MEN1	O00255-1.4	P475T	Neutral	0.0
MEN1	O00255-1.4	P475V	Neutral	0.001
MEN1	O00255-1.4	P475W	Neutral	0.342
MEN1	O00255-1.4	P475Y	Neutral	0.012
MEN1	O00255-1.4	W476A	Pathogenic	0.998
MEN1	O00255-1.4	W476C	Pathogenic	0.971
MEN1	O00255-1.4	W476D	Pathogenic	0.998
MEN1	O00255-1.4	W476E	Pathogenic	0.989
MEN1	O00255-1.4	W476F	Neutral	0.163
MEN1	O00255-1.4	W476G	Pathogenic	1.0
MEN1	O00255-1.4	W476H	Pathogenic	0.924
MEN1	O00255-1.4	W476I	Neutral	0.355
MEN1	O00255-1.4	W476K	Pathogenic	0.957
MEN1	O00255-1.4	W476L	Neutral	0.38
MEN1	O00255-1.4	W476M	Pathogenic	0.553
MEN1	O00255-1.4	W476N	Pathogenic	0.996
MEN1	O00255-1.4	W476P	Pathogenic	0.977
MEN1	O00255-1.4	W476Q	Pathogenic	0.967
MEN1	O00255-1.4	W476R	Pathogenic	0.897
MEN1	O00255-1.4	W476S	Pathogenic	0.998
MEN1	O00255-1.4	W476T	Pathogenic	0.985
MEN1	O00255-1.4	W476V	Pathogenic	0.855
MEN1	O00255-1.4	W476Y	Neutral	0.31
MEN1	O00255-1.4	G477A	Neutral	0.006
MEN1	O00255-1.4	G477C	Neutral	0.082
MEN1	O00255-1.4	G477D	Neutral	0.076
MEN1	O00255-1.4	G477E	Neutral	0.212
MEN1	O00255-1.4	G477F	Pathogenic	0.928
MEN1	O00255-1.4	G477H	Neutral	0.188
MEN1	O00255-1.4	G477I	Pathogenic	0.86
MEN1	O00255-1.4	G477K	Pathogenic	0.768
MEN1	O00255-1.4	G477L	Pathogenic	0.839
MEN1	O00255-1.4	G477M	Pathogenic	0.696
MEN1	O00255-1.4	G477N	Neutral	0.078
MEN1	O00255-1.4	G477P	Neutral	0.069
MEN1	O00255-1.4	G477Q	Neutral	0.165
MEN1	O00255-1.4	G477R	Pathogenic	0.9
MEN1	O00255-1.4	G477S	Neutral	0.006
MEN1	O00255-1.4	G477T	Neutral	0.042
MEN1	O00255-1.4	G477V	Neutral	0.351
MEN1	O00255-1.4	G477W	Pathogenic	0.995
MEN1	O00255-1.4	G477Y	Pathogenic	0.84
MEN1	O00255-1.4	E478A	Neutral	0.224
MEN1	O00255-1.4	E478C	Neutral	0.199
MEN1	O00255-1.4	E478D	Neutral	0.011
MEN1	O00255-1.4	E478F	Pathogenic	0.521
MEN1	O00255-1.4	E478G	Neutral	0.434
MEN1	O00255-1.4	E478H	Neutral	0.017
MEN1	O00255-1.4	E478I	Neutral	0.328
MEN1	O00255-1.4	E478K	Neutral	0.029
MEN1	O00255-1.4	E478L	Neutral	0.293
MEN1	O00255-1.4	E478M	Neutral	0.154
MEN1	O00255-1.4	E478N	Neutral	0.007
MEN1	O00255-1.4	E478P	Neutral	0.091
MEN1	O00255-1.4	E478Q	Neutral	0.006
MEN1	O00255-1.4	E478R	Neutral	0.078
MEN1	O00255-1.4	E478S	Neutral	0.09
MEN1	O00255-1.4	E478T	Neutral	0.037
MEN1	O00255-1.4	E478V	Neutral	0.073
MEN1	O00255-1.4	E478W	Pathogenic	0.949
MEN1	O00255-1.4	E478Y	Neutral	0.295
MEN1	O00255-1.4	E479A	Neutral	0.095
MEN1	O00255-1.4	E479C	Neutral	0.083
MEN1	O00255-1.4	E479D	Neutral	0.004
MEN1	O00255-1.4	E479F	Neutral	0.284
MEN1	O00255-1.4	E479G	Neutral	0.219
MEN1	O00255-1.4	E479H	Neutral	0.006
MEN1	O00255-1.4	E479I	Neutral	0.151
MEN1	O00255-1.4	E479K	Neutral	0.011
MEN1	O00255-1.4	E479L	Neutral	0.131
MEN1	O00255-1.4	E479M	Neutral	0.062
MEN1	O00255-1.4	E479N	Neutral	0.003
MEN1	O00255-1.4	E479P	Neutral	0.035
MEN1	O00255-1.4	E479Q	Neutral	0.002
MEN1	O00255-1.4	E479R	Neutral	0.03
MEN1	O00255-1.4	E479S	Neutral	0.035
MEN1	O00255-1.4	E479T	Neutral	0.014
MEN1	O00255-1.4	E479V	Neutral	0.028
MEN1	O00255-1.4	E479W	Pathogenic	0.872
MEN1	O00255-1.4	E479Y	Neutral	0.132
MEN1	O00255-1.4	A480C	Neutral	0.002
MEN1	O00255-1.4	A480D	Neutral	0.005
MEN1	O00255-1.4	A480E	Neutral	0.016
MEN1	O00255-1.4	A480F	Neutral	0.219
MEN1	O00255-1.4	A480G	Neutral	0.001
MEN1	O00255-1.4	A480H	Neutral	0.009
MEN1	O00255-1.4	A480I	Neutral	0.106
MEN1	O00255-1.4	A480K	Neutral	0.164
MEN1	O00255-1.4	A480L	Neutral	0.091
MEN1	O00255-1.4	A480M	Neutral	0.045
MEN1	O00255-1.4	A480N	Neutral	0.006
MEN1	O00255-1.4	A480P	Neutral	0.002
MEN1	O00255-1.4	A480Q	Neutral	0.012
MEN1	O00255-1.4	A480R	Neutral	0.347
MEN1	O00255-1.4	A480S	Neutral	0.0
MEN1	O00255-1.4	A480T	Neutral	0.001
MEN1	O00255-1.4	A480V	Neutral	0.01
MEN1	O00255-1.4	A480W	Pathogenic	0.836
MEN1	O00255-1.4	A480Y	Neutral	0.103
MEN1	O00255-1.4	R481A	Pathogenic	0.948
MEN1	O00255-1.4	R481C	Pathogenic	0.937
MEN1	O00255-1.4	R481D	Neutral	0.36
MEN1	O00255-1.4	R481E	Neutral	0.139
MEN1	O00255-1.4	R481F	Pathogenic	0.586
MEN1	O00255-1.4	R481G	Pathogenic	0.98
MEN1	O00255-1.4	R481H	Neutral	0.223
MEN1	O00255-1.4	R481I	Pathogenic	0.768
MEN1	O00255-1.4	R481K	Neutral	0.011
MEN1	O00255-1.4	R481L	Pathogenic	0.725
MEN1	O00255-1.4	R481M	Pathogenic	0.537
MEN1	O00255-1.4	R481N	Neutral	0.311
MEN1	O00255-1.4	R481P	Pathogenic	0.871
MEN1	O00255-1.4	R481Q	Neutral	0.171
MEN1	O00255-1.4	R481S	Pathogenic	0.87
MEN1	O00255-1.4	R481T	Pathogenic	0.707
MEN1	O00255-1.4	R481V	Pathogenic	0.841
MEN1	O00255-1.4	R481W	Pathogenic	0.777
MEN1	O00255-1.4	R481Y	Neutral	0.182
MEN1	O00255-1.4	E482A	Pathogenic	0.552
MEN1	O00255-1.4	E482C	Pathogenic	0.516
MEN1	O00255-1.4	E482D	Neutral	0.044
MEN1	O00255-1.4	E482F	Pathogenic	0.823
MEN1	O00255-1.4	E482G	Pathogenic	0.767
MEN1	O00255-1.4	E482H	Neutral	0.069
MEN1	O00255-1.4	E482I	Pathogenic	0.677
MEN1	O00255-1.4	E482K	Neutral	0.112
MEN1	O00255-1.4	E482L	Pathogenic	0.639
MEN1	O00255-1.4	E482M	Neutral	0.438
MEN1	O00255-1.4	E482N	Neutral	0.03
MEN1	O00255-1.4	E482P	Neutral	0.301
MEN1	O00255-1.4	E482Q	Neutral	0.027
MEN1	O00255-1.4	E482R	Neutral	0.266
MEN1	O00255-1.4	E482S	Neutral	0.298
MEN1	O00255-1.4	E482T	Neutral	0.14
MEN1	O00255-1.4	E482V	Neutral	0.251
MEN1	O00255-1.4	E482W	Pathogenic	0.988
MEN1	O00255-1.4	E482Y	Pathogenic	0.641
MEN1	O00255-1.4	G483A	Neutral	0.014
MEN1	O00255-1.4	G483C	Neutral	0.172
MEN1	O00255-1.4	G483D	Neutral	0.159
MEN1	O00255-1.4	G483E	Neutral	0.384
MEN1	O00255-1.4	G483F	Pathogenic	0.968
MEN1	O00255-1.4	G483H	Neutral	0.349
MEN1	O00255-1.4	G483I	Pathogenic	0.934
MEN1	O00255-1.4	G483K	Pathogenic	0.885
MEN1	O00255-1.4	G483L	Pathogenic	0.924
MEN1	O00255-1.4	G483M	Pathogenic	0.842
MEN1	O00255-1.4	G483N	Neutral	0.165
MEN1	O00255-1.4	G483P	Neutral	0.147
MEN1	O00255-1.4	G483Q	Neutral	0.315
MEN1	O00255-1.4	G483R	Pathogenic	0.954
MEN1	O00255-1.4	G483S	Neutral	0.014
MEN1	O00255-1.4	G483T	Neutral	0.092
MEN1	O00255-1.4	G483V	Pathogenic	0.556
MEN1	O00255-1.4	G483W	Pathogenic	0.998
MEN1	O00255-1.4	G483Y	Pathogenic	0.924
MEN1	O00255-1.4	R484A	Pathogenic	0.96
MEN1	O00255-1.4	R484C	Pathogenic	0.952
MEN1	O00255-1.4	R484D	Neutral	0.428
MEN1	O00255-1.4	R484E	Neutral	0.177
MEN1	O00255-1.4	R484F	Pathogenic	0.654
MEN1	O00255-1.4	R484G	Pathogenic	0.985
MEN1	O00255-1.4	R484H	Neutral	0.276
MEN1	O00255-1.4	R484I	Pathogenic	0.815
MEN1	O00255-1.4	R484K	Neutral	0.015
MEN1	O00255-1.4	R484L	Pathogenic	0.778
MEN1	O00255-1.4	R484M	Pathogenic	0.606
MEN1	O00255-1.4	R484N	Neutral	0.375
MEN1	O00255-1.4	R484P	Pathogenic	0.9
MEN1	O00255-1.4	R484Q	Neutral	0.215
MEN1	O00255-1.4	R484S	Pathogenic	0.899
MEN1	O00255-1.4	R484T	Pathogenic	0.762
MEN1	O00255-1.4	R484V	Pathogenic	0.875
MEN1	O00255-1.4	R484W	Pathogenic	0.823
MEN1	O00255-1.4	R484Y	Neutral	0.228
MEN1	O00255-1.4	R485A	Pathogenic	0.958
MEN1	O00255-1.4	R485C	Pathogenic	0.949
MEN1	O00255-1.4	R485D	Neutral	0.411
MEN1	O00255-1.4	R485E	Neutral	0.167
MEN1	O00255-1.4	R485F	Pathogenic	0.638
MEN1	O00255-1.4	R485G	Pathogenic	0.984
MEN1	O00255-1.4	R485H	Neutral	0.262
MEN1	O00255-1.4	R485I	Pathogenic	0.804
MEN1	O00255-1.4	R485K	Neutral	0.014
MEN1	O00255-1.4	R485L	Pathogenic	0.766
MEN1	O00255-1.4	R485M	Pathogenic	0.59
MEN1	O00255-1.4	R485N	Neutral	0.359
MEN1	O00255-1.4	R485P	Pathogenic	0.894
MEN1	O00255-1.4	R485Q	Neutral	0.203
MEN1	O00255-1.4	R485S	Pathogenic	0.892
MEN1	O00255-1.4	R485T	Pathogenic	0.75
MEN1	O00255-1.4	R485V	Pathogenic	0.867
MEN1	O00255-1.4	R485W	Pathogenic	0.812
MEN1	O00255-1.4	R485Y	Neutral	0.216
MEN1	O00255-1.4	R486A	Pathogenic	0.964
MEN1	O00255-1.4	R486C	Pathogenic	0.956
MEN1	O00255-1.4	R486D	Neutral	0.45
MEN1	O00255-1.4	R486E	Neutral	0.19
MEN1	O00255-1.4	R486F	Pathogenic	0.673
MEN1	O00255-1.4	R486G	Pathogenic	0.986
MEN1	O00255-1.4	R486H	Neutral	0.294
MEN1	O00255-1.4	R486I	Pathogenic	0.828
MEN1	O00255-1.4	R486K	Neutral	0.017
MEN1	O00255-1.4	R486L	Pathogenic	0.793
MEN1	O00255-1.4	R486M	Pathogenic	0.627
MEN1	O00255-1.4	R486N	Neutral	0.396
MEN1	O00255-1.4	R486P	Pathogenic	0.908
MEN1	O00255-1.4	R486Q	Neutral	0.23
MEN1	O00255-1.4	R486S	Pathogenic	0.907
MEN1	O00255-1.4	R486T	Pathogenic	0.778
MEN1	O00255-1.4	R486V	Pathogenic	0.885
MEN1	O00255-1.4	R486W	Pathogenic	0.835
MEN1	O00255-1.4	R486Y	Neutral	0.244
MEN1	O00255-1.4	G487A	Neutral	0.071
MEN1	O00255-1.4	G487C	Pathogenic	0.532
MEN1	O00255-1.4	G487D	Pathogenic	0.509
MEN1	O00255-1.4	G487E	Pathogenic	0.773
MEN1	O00255-1.4	G487F	Pathogenic	0.994
MEN1	O00255-1.4	G487H	Pathogenic	0.746
MEN1	O00255-1.4	G487I	Pathogenic	0.987
MEN1	O00255-1.4	G487K	Pathogenic	0.977
MEN1	O00255-1.4	G487L	Pathogenic	0.985
MEN1	O00255-1.4	G487M	Pathogenic	0.967
MEN1	O00255-1.4	G487N	Pathogenic	0.519
MEN1	O00255-1.4	G487P	Neutral	0.484
MEN1	O00255-1.4	G487Q	Pathogenic	0.715
MEN1	O00255-1.4	G487R	Pathogenic	0.991
MEN1	O00255-1.4	G487S	Neutral	0.072
MEN1	O00255-1.4	G487T	Neutral	0.357
MEN1	O00255-1.4	G487V	Pathogenic	0.873
MEN1	O00255-1.4	G487W	Pathogenic	1.0
MEN1	O00255-1.4	G487Y	Pathogenic	0.985
MEN1	O00255-1.4	P488A	Neutral	0.038
MEN1	O00255-1.4	P488C	Neutral	0.008
MEN1	O00255-1.4	P488D	Neutral	0.042
MEN1	O00255-1.4	P488E	Neutral	0.12
MEN1	O00255-1.4	P488F	Neutral	0.417
MEN1	O00255-1.4	P488G	Neutral	0.223
MEN1	O00255-1.4	P488H	Neutral	0.075
MEN1	O00255-1.4	P488I	Neutral	0.233
MEN1	O00255-1.4	P488K	Pathogenic	0.627
MEN1	O00255-1.4	P488L	Neutral	0.204
MEN1	O00255-1.4	P488M	Neutral	0.102
MEN1	O00255-1.4	P488N	Neutral	0.049
MEN1	O00255-1.4	P488Q	Neutral	0.091
MEN1	O00255-1.4	P488R	Pathogenic	0.828
MEN1	O00255-1.4	P488S	Neutral	0.042
MEN1	O00255-1.4	P488T	Neutral	0.01
MEN1	O00255-1.4	P488V	Neutral	0.026
MEN1	O00255-1.4	P488W	Pathogenic	0.925
MEN1	O00255-1.4	P488Y	Neutral	0.216
MEN1	O00255-1.4	R489A	Pathogenic	0.93
MEN1	O00255-1.4	R489C	Pathogenic	0.915
MEN1	O00255-1.4	R489D	Neutral	0.289
MEN1	O00255-1.4	R489E	Neutral	0.104
MEN1	O00255-1.4	R489F	Pathogenic	0.506
MEN1	O00255-1.4	R489G	Pathogenic	0.972
MEN1	O00255-1.4	R489H	Neutral	0.172
MEN1	O00255-1.4	R489I	Pathogenic	0.705
MEN1	O00255-1.4	R489K	Neutral	0.008
MEN1	O00255-1.4	R489L	Pathogenic	0.655
MEN1	O00255-1.4	R489M	Neutral	0.456
MEN1	O00255-1.4	R489N	Neutral	0.246
MEN1	O00255-1.4	R489P	Pathogenic	0.83
MEN1	O00255-1.4	R489Q	Neutral	0.129
MEN1	O00255-1.4	R489S	Pathogenic	0.828
MEN1	O00255-1.4	R489T	Pathogenic	0.635
MEN1	O00255-1.4	R489V	Pathogenic	0.792
MEN1	O00255-1.4	R489W	Pathogenic	0.716
MEN1	O00255-1.4	R489Y	Neutral	0.139
MEN1	O00255-1.4	R490A	Pathogenic	0.925
MEN1	O00255-1.4	R490C	Pathogenic	0.91
MEN1	O00255-1.4	R490D	Neutral	0.276
MEN1	O00255-1.4	R490E	Neutral	0.098
MEN1	O00255-1.4	R490F	Neutral	0.49
MEN1	O00255-1.4	R490G	Pathogenic	0.971
MEN1	O00255-1.4	R490H	Neutral	0.163
MEN1	O00255-1.4	R490I	Pathogenic	0.691
MEN1	O00255-1.4	R490K	Neutral	0.008
MEN1	O00255-1.4	R490L	Pathogenic	0.641
MEN1	O00255-1.4	R490M	Neutral	0.44
MEN1	O00255-1.4	R490N	Neutral	0.234
MEN1	O00255-1.4	R490P	Pathogenic	0.821
MEN1	O00255-1.4	R490Q	Neutral	0.122
MEN1	O00255-1.4	R490S	Pathogenic	0.819
MEN1	O00255-1.4	R490T	Pathogenic	0.62
MEN1	O00255-1.4	R490V	Pathogenic	0.781
MEN1	O00255-1.4	R490W	Pathogenic	0.702
MEN1	O00255-1.4	R490Y	Neutral	0.131
MEN1	O00255-1.4	E491A	Pathogenic	0.512
MEN1	O00255-1.4	E491C	Neutral	0.476
MEN1	O00255-1.4	E491D	Neutral	0.037
MEN1	O00255-1.4	E491F	Pathogenic	0.798
MEN1	O00255-1.4	E491G	Pathogenic	0.736
MEN1	O00255-1.4	E491H	Neutral	0.059
MEN1	O00255-1.4	E491I	Pathogenic	0.64
MEN1	O00255-1.4	E491K	Neutral	0.097
MEN1	O00255-1.4	E491L	Pathogenic	0.601
MEN1	O00255-1.4	E491M	Neutral	0.399
MEN1	O00255-1.4	E491N	Neutral	0.025
MEN1	O00255-1.4	E491P	Neutral	0.268
MEN1	O00255-1.4	E491Q	Neutral	0.023
MEN1	O00255-1.4	E491R	Neutral	0.236
MEN1	O00255-1.4	E491S	Neutral	0.265
MEN1	O00255-1.4	E491T	Neutral	0.122
MEN1	O00255-1.4	E491V	Neutral	0.222
MEN1	O00255-1.4	E491W	Pathogenic	0.985
MEN1	O00255-1.4	E491Y	Pathogenic	0.603
MEN1	O00255-1.4	S492A	Neutral	0.297
MEN1	O00255-1.4	S492C	Pathogenic	0.706
MEN1	O00255-1.4	S492D	Pathogenic	0.674
MEN1	O00255-1.4	S492E	Pathogenic	0.865
MEN1	O00255-1.4	S492F	Pathogenic	0.997
MEN1	O00255-1.4	S492G	Pathogenic	0.53
MEN1	O00255-1.4	S492H	Pathogenic	0.868
MEN1	O00255-1.4	S492I	Pathogenic	0.994
MEN1	O00255-1.4	S492K	Pathogenic	0.987
MEN1	O00255-1.4	S492L	Pathogenic	0.993
MEN1	O00255-1.4	S492M	Pathogenic	0.984
MEN1	O00255-1.4	S492N	Pathogenic	0.683
MEN1	O00255-1.4	S492P	Pathogenic	0.678
MEN1	O00255-1.4	S492Q	Pathogenic	0.825
MEN1	O00255-1.4	S492R	Pathogenic	0.996
MEN1	O00255-1.4	S492T	Pathogenic	0.525
MEN1	O00255-1.4	S492V	Pathogenic	0.939
MEN1	O00255-1.4	S492W	Pathogenic	1.0
MEN1	O00255-1.4	S492Y	Pathogenic	0.993
MEN1	O00255-1.4	K493A	Pathogenic	0.949
MEN1	O00255-1.4	K493C	Pathogenic	0.938
MEN1	O00255-1.4	K493D	Neutral	0.351
MEN1	O00255-1.4	K493E	Neutral	0.134
MEN1	O00255-1.4	K493F	Pathogenic	0.592
MEN1	O00255-1.4	K493G	Pathogenic	0.98
MEN1	O00255-1.4	K493H	Neutral	0.237
MEN1	O00255-1.4	K493I	Pathogenic	0.771
MEN1	O00255-1.4	K493L	Pathogenic	0.729
MEN1	O00255-1.4	K493M	Pathogenic	0.542
MEN1	O00255-1.4	K493N	Neutral	0.316
MEN1	O00255-1.4	K493P	Pathogenic	0.867
MEN1	O00255-1.4	K493Q	Neutral	0.174
MEN1	O00255-1.4	K493R	Neutral	0.031
MEN1	O00255-1.4	K493S	Pathogenic	0.865
MEN1	O00255-1.4	K493T	Pathogenic	0.711
MEN1	O00255-1.4	K493V	Pathogenic	0.835
MEN1	O00255-1.4	K493W	Pathogenic	0.961
MEN1	O00255-1.4	K493Y	Neutral	0.358
MEN1	O00255-1.4	P494A	Neutral	0.02
MEN1	O00255-1.4	P494C	Neutral	0.004
MEN1	O00255-1.4	P494D	Neutral	0.023
MEN1	O00255-1.4	P494E	Neutral	0.067
MEN1	O00255-1.4	P494F	Neutral	0.274
MEN1	O00255-1.4	P494G	Neutral	0.131
MEN1	O00255-1.4	P494H	Neutral	0.041
MEN1	O00255-1.4	P494I	Neutral	0.138
MEN1	O00255-1.4	P494K	Neutral	0.47
MEN1	O00255-1.4	P494L	Neutral	0.119
MEN1	O00255-1.4	P494M	Neutral	0.056
MEN1	O00255-1.4	P494N	Neutral	0.027
MEN1	O00255-1.4	P494Q	Neutral	0.05
MEN1	O00255-1.4	P494R	Pathogenic	0.718
MEN1	O00255-1.4	P494S	Neutral	0.023
MEN1	O00255-1.4	P494T	Neutral	0.005
MEN1	O00255-1.4	P494V	Neutral	0.014
MEN1	O00255-1.4	P494W	Pathogenic	0.866
MEN1	O00255-1.4	P494Y	Neutral	0.127
MEN1	O00255-1.4	E495A	Neutral	0.189
MEN1	O00255-1.4	E495C	Neutral	0.168
MEN1	O00255-1.4	E495D	Neutral	0.009
MEN1	O00255-1.4	E495F	Neutral	0.468
MEN1	O00255-1.4	E495G	Neutral	0.383
MEN1	O00255-1.4	E495H	Neutral	0.014
MEN1	O00255-1.4	E495I	Neutral	0.284
MEN1	O00255-1.4	E495K	Neutral	0.023
MEN1	O00255-1.4	E495L	Neutral	0.251
MEN1	O00255-1.4	E495M	Neutral	0.128
MEN1	O00255-1.4	E495N	Neutral	0.006
MEN1	O00255-1.4	E495P	Neutral	0.075
MEN1	O00255-1.4	E495Q	Neutral	0.005
MEN1	O00255-1.4	E495R	Neutral	0.064
MEN1	O00255-1.4	E495S	Neutral	0.074
MEN1	O00255-1.4	E495T	Neutral	0.03
MEN1	O00255-1.4	E495V	Neutral	0.06
MEN1	O00255-1.4	E495W	Pathogenic	0.938
MEN1	O00255-1.4	E495Y	Neutral	0.253
MEN1	O00255-1.4	E496A	Neutral	0.114
MEN1	O00255-1.4	E496C	Neutral	0.1
MEN1	O00255-1.4	E496D	Neutral	0.005
MEN1	O00255-1.4	E496F	Neutral	0.326
MEN1	O00255-1.4	E496G	Neutral	0.255
MEN1	O00255-1.4	E496H	Neutral	0.008
MEN1	O00255-1.4	E496I	Neutral	0.179
MEN1	O00255-1.4	E496K	Neutral	0.013
MEN1	O00255-1.4	E496L	Neutral	0.156
MEN1	O00255-1.4	E496M	Neutral	0.075
MEN1	O00255-1.4	E496N	Neutral	0.003
MEN1	O00255-1.4	E496P	Neutral	0.043
MEN1	O00255-1.4	E496Q	Neutral	0.003
MEN1	O00255-1.4	E496R	Neutral	0.036
MEN1	O00255-1.4	E496S	Neutral	0.042
MEN1	O00255-1.4	E496T	Neutral	0.017
MEN1	O00255-1.4	E496V	Neutral	0.034
MEN1	O00255-1.4	E496W	Pathogenic	0.892
MEN1	O00255-1.4	E496Y	Neutral	0.157
MEN1	O00255-1.4	P497A	Neutral	0.065
MEN1	O00255-1.4	P497C	Neutral	0.015
MEN1	O00255-1.4	P497D	Neutral	0.072
MEN1	O00255-1.4	P497E	Neutral	0.194
MEN1	O00255-1.4	P497F	Pathogenic	0.558
MEN1	O00255-1.4	P497G	Neutral	0.335
MEN1	O00255-1.4	P497H	Neutral	0.125
MEN1	O00255-1.4	P497I	Neutral	0.348
MEN1	O00255-1.4	P497K	Pathogenic	0.748
MEN1	O00255-1.4	P497L	Neutral	0.312
MEN1	O00255-1.4	P497M	Neutral	0.166
MEN1	O00255-1.4	P497N	Neutral	0.083
MEN1	O00255-1.4	P497Q	Neutral	0.15
MEN1	O00255-1.4	P497R	Pathogenic	0.895
MEN1	O00255-1.4	P497S	Neutral	0.072
MEN1	O00255-1.4	P497T	Neutral	0.017
MEN1	O00255-1.4	P497V	Neutral	0.045
MEN1	O00255-1.4	P497W	Pathogenic	0.956
MEN1	O00255-1.4	P497Y	Neutral	0.326
MEN1	O00255-1.4	P498A	Neutral	0.11
MEN1	O00255-1.4	P498C	Neutral	0.026
MEN1	O00255-1.4	P498D	Neutral	0.12
MEN1	O00255-1.4	P498E	Neutral	0.298
MEN1	O00255-1.4	P498F	Pathogenic	0.69
MEN1	O00255-1.4	P498G	Neutral	0.471
MEN1	O00255-1.4	P498H	Neutral	0.202
MEN1	O00255-1.4	P498I	Neutral	0.486
MEN1	O00255-1.4	P498K	Pathogenic	0.839
MEN1	O00255-1.4	P498L	Neutral	0.444
MEN1	O00255-1.4	P498M	Neutral	0.26
MEN1	O00255-1.4	P498N	Neutral	0.138
MEN1	O00255-1.4	P498Q	Neutral	0.238
MEN1	O00255-1.4	P498R	Pathogenic	0.938
MEN1	O00255-1.4	P498S	Neutral	0.121
MEN1	O00255-1.4	P498T	Neutral	0.029
MEN1	O00255-1.4	P498V	Neutral	0.077
MEN1	O00255-1.4	P498W	Pathogenic	0.974
MEN1	O00255-1.4	P498Y	Neutral	0.461
MEN1	O00255-1.4	P499A	Neutral	0.019
MEN1	O00255-1.4	P499C	Neutral	0.004
MEN1	O00255-1.4	P499D	Neutral	0.021
MEN1	O00255-1.4	P499E	Neutral	0.062
MEN1	O00255-1.4	P499F	Neutral	0.259
MEN1	O00255-1.4	P499G	Neutral	0.123
MEN1	O00255-1.4	P499H	Neutral	0.038
MEN1	O00255-1.4	P499I	Neutral	0.129
MEN1	O00255-1.4	P499K	Neutral	0.451
MEN1	O00255-1.4	P499L	Neutral	0.112
MEN1	O00255-1.4	P499M	Neutral	0.052
MEN1	O00255-1.4	P499N	Neutral	0.025
MEN1	O00255-1.4	P499Q	Neutral	0.047
MEN1	O00255-1.4	P499R	Pathogenic	0.702
MEN1	O00255-1.4	P499S	Neutral	0.021
MEN1	O00255-1.4	P499T	Neutral	0.005
MEN1	O00255-1.4	P499V	Neutral	0.013
MEN1	O00255-1.4	P499W	Pathogenic	0.857
MEN1	O00255-1.4	P499Y	Neutral	0.119
MEN1	O00255-1.4	P500A	Neutral	0.038
MEN1	O00255-1.4	P500C	Neutral	0.008
MEN1	O00255-1.4	P500D	Neutral	0.042
MEN1	O00255-1.4	P500E	Neutral	0.12
MEN1	O00255-1.4	P500F	Neutral	0.417
MEN1	O00255-1.4	P500G	Neutral	0.223
MEN1	O00255-1.4	P500H	Neutral	0.075
MEN1	O00255-1.4	P500I	Neutral	0.233
MEN1	O00255-1.4	P500K	Pathogenic	0.627
MEN1	O00255-1.4	P500L	Neutral	0.205
MEN1	O00255-1.4	P500M	Neutral	0.102
MEN1	O00255-1.4	P500N	Neutral	0.049
MEN1	O00255-1.4	P500Q	Neutral	0.091
MEN1	O00255-1.4	P500R	Pathogenic	0.829
MEN1	O00255-1.4	P500S	Neutral	0.042
MEN1	O00255-1.4	P500T	Neutral	0.01
MEN1	O00255-1.4	P500V	Neutral	0.026
MEN1	O00255-1.4	P500W	Pathogenic	0.925
MEN1	O00255-1.4	P500Y	Neutral	0.216
MEN1	O00255-1.4	K501A	Neutral	0.456
MEN1	O00255-1.4	K501C	Neutral	0.406
MEN1	O00255-1.4	K501D	Neutral	0.024
MEN1	O00255-1.4	K501E	Neutral	0.007
MEN1	O00255-1.4	K501F	Neutral	0.061
MEN1	O00255-1.4	K501G	Pathogenic	0.691
MEN1	O00255-1.4	K501H	Neutral	0.014
MEN1	O00255-1.4	K501I	Neutral	0.132
MEN1	O00255-1.4	K501L	Neutral	0.108
MEN1	O00255-1.4	K501M	Neutral	0.05
MEN1	O00255-1.4	K501N	Neutral	0.02
MEN1	O00255-1.4	K501P	Neutral	0.227
MEN1	O00255-1.4	K501Q	Neutral	0.009
MEN1	O00255-1.4	K501R	Neutral	0.001
MEN1	O00255-1.4	K501S	Neutral	0.224
MEN1	O00255-1.4	K501T	Neutral	0.1
MEN1	O00255-1.4	K501V	Neutral	0.186
MEN1	O00255-1.4	K501W	Pathogenic	0.527
MEN1	O00255-1.4	K501Y	Neutral	0.024
MEN1	O00255-1.4	K502A	Neutral	0.464
MEN1	O00255-1.4	K502C	Neutral	0.414
MEN1	O00255-1.4	K502D	Neutral	0.025
MEN1	O00255-1.4	K502E	Neutral	0.007
MEN1	O00255-1.4	K502F	Neutral	0.063
MEN1	O00255-1.4	K502G	Pathogenic	0.698
MEN1	O00255-1.4	K502H	Neutral	0.014
MEN1	O00255-1.4	K502I	Neutral	0.135
MEN1	O00255-1.4	K502L	Neutral	0.111
MEN1	O00255-1.4	K502M	Neutral	0.052
MEN1	O00255-1.4	K502N	Neutral	0.021
MEN1	O00255-1.4	K502P	Neutral	0.232
MEN1	O00255-1.4	K502Q	Neutral	0.01
MEN1	O00255-1.4	K502R	Neutral	0.001
MEN1	O00255-1.4	K502S	Neutral	0.23
MEN1	O00255-1.4	K502T	Neutral	0.103
MEN1	O00255-1.4	K502V	Neutral	0.191
MEN1	O00255-1.4	K502W	Pathogenic	0.535
MEN1	O00255-1.4	K502Y	Neutral	0.025
MEN1	O00255-1.4	P503A	Neutral	0.015
MEN1	O00255-1.4	P503C	Neutral	0.003
MEN1	O00255-1.4	P503D	Neutral	0.017
MEN1	O00255-1.4	P503E	Neutral	0.051
MEN1	O00255-1.4	P503F	Neutral	0.218
MEN1	O00255-1.4	P503G	Neutral	0.101
MEN1	O00255-1.4	P503H	Neutral	0.031
MEN1	O00255-1.4	P503I	Neutral	0.106
MEN1	O00255-1.4	P503K	Neutral	0.396
MEN1	O00255-1.4	P503L	Neutral	0.091
MEN1	O00255-1.4	P503M	Neutral	0.042
MEN1	O00255-1.4	P503N	Neutral	0.02
MEN1	O00255-1.4	P503Q	Neutral	0.038
MEN1	O00255-1.4	P503R	Pathogenic	0.653
MEN1	O00255-1.4	P503S	Neutral	0.017
MEN1	O00255-1.4	P503T	Neutral	0.004
MEN1	O00255-1.4	P503V	Neutral	0.01
MEN1	O00255-1.4	P503W	Pathogenic	0.827
MEN1	O00255-1.4	P503Y	Neutral	0.097
MEN1	O00255-1.4	A504C	Neutral	0.008
MEN1	O00255-1.4	A504D	Neutral	0.023
MEN1	O00255-1.4	A504E	Neutral	0.065
MEN1	O00255-1.4	A504F	Pathogenic	0.553
MEN1	O00255-1.4	A504G	Neutral	0.004
MEN1	O00255-1.4	A504H	Neutral	0.04
MEN1	O00255-1.4	A504I	Neutral	0.344
MEN1	O00255-1.4	A504K	Neutral	0.464
MEN1	O00255-1.4	A504L	Neutral	0.307
MEN1	O00255-1.4	A504M	Neutral	0.172
MEN1	O00255-1.4	A504N	Neutral	0.026
MEN1	O00255-1.4	A504P	Neutral	0.007
MEN1	O00255-1.4	A504Q	Neutral	0.049
MEN1	O00255-1.4	A504R	Pathogenic	0.7
MEN1	O00255-1.4	A504S	Neutral	0.002
MEN1	O00255-1.4	A504T	Neutral	0.005
MEN1	O00255-1.4	A504V	Neutral	0.044
MEN1	O00255-1.4	A504W	Pathogenic	0.957
MEN1	O00255-1.4	A504Y	Neutral	0.335
MEN1	O00255-1.4	L505A	Neutral	0.044
MEN1	O00255-1.4	L505C	Neutral	0.004
MEN1	O00255-1.4	L505D	Neutral	0.05
MEN1	O00255-1.4	L505E	Neutral	0.01
MEN1	O00255-1.4	L505F	Neutral	0.0
MEN1	O00255-1.4	L505G	Neutral	0.274
MEN1	O00255-1.4	L505H	Neutral	0.002
MEN1	O00255-1.4	L505I	Neutral	0.0
MEN1	O00255-1.4	L505K	Neutral	0.013
MEN1	O00255-1.4	L505M	Neutral	0.0
MEN1	O00255-1.4	L505N	Neutral	0.025
MEN1	O00255-1.4	L505P	Neutral	0.005
MEN1	O00255-1.4	L505Q	Neutral	0.003
MEN1	O00255-1.4	L505R	Neutral	0.034
MEN1	O00255-1.4	L505S	Neutral	0.052
MEN1	O00255-1.4	L505T	Neutral	0.007
MEN1	O00255-1.4	L505V	Neutral	0.001
MEN1	O00255-1.4	L505W	Neutral	0.003
MEN1	O00255-1.4	L505Y	Neutral	0.001
MEN1	O00255-1.4	D506A	Neutral	0.007
MEN1	O00255-1.4	D506C	Neutral	0.005
MEN1	O00255-1.4	D506E	Neutral	0.001
MEN1	O00255-1.4	D506F	Neutral	0.26
MEN1	O00255-1.4	D506G	Neutral	0.016
MEN1	O00255-1.4	D506H	Neutral	0.006
MEN1	O00255-1.4	D506I	Neutral	0.137
MEN1	O00255-1.4	D506K	Neutral	0.007
MEN1	O00255-1.4	D506L	Neutral	0.125
MEN1	O00255-1.4	D506M	Neutral	0.059
MEN1	O00255-1.4	D506N	Neutral	0.0
MEN1	O00255-1.4	D506P	Neutral	0.002
MEN1	O00255-1.4	D506Q	Neutral	0.002
MEN1	O00255-1.4	D506R	Neutral	0.02
MEN1	O00255-1.4	D506S	Neutral	0.002
MEN1	O00255-1.4	D506T	Neutral	0.001
MEN1	O00255-1.4	D506V	Neutral	0.015
MEN1	O00255-1.4	D506W	Pathogenic	0.865
MEN1	O00255-1.4	D506Y	Neutral	0.126
MEN1	O00255-1.4	K507A	Neutral	0.396
MEN1	O00255-1.4	K507C	Neutral	0.348
MEN1	O00255-1.4	K507D	Neutral	0.019
MEN1	O00255-1.4	K507E	Neutral	0.005
MEN1	O00255-1.4	K507F	Neutral	0.048
MEN1	O00255-1.4	K507G	Pathogenic	0.636
MEN1	O00255-1.4	K507H	Neutral	0.011
MEN1	O00255-1.4	K507I	Neutral	0.106
MEN1	O00255-1.4	K507L	Neutral	0.086
MEN1	O00255-1.4	K507M	Neutral	0.04
MEN1	O00255-1.4	K507N	Neutral	0.016
MEN1	O00255-1.4	K507P	Neutral	0.186
MEN1	O00255-1.4	K507Q	Neutral	0.007
MEN1	O00255-1.4	K507R	Neutral	0.001
MEN1	O00255-1.4	K507S	Neutral	0.184
MEN1	O00255-1.4	K507T	Neutral	0.08
MEN1	O00255-1.4	K507V	Neutral	0.151
MEN1	O00255-1.4	K507W	Neutral	0.466
MEN1	O00255-1.4	K507Y	Neutral	0.019
MEN1	O00255-1.4	G508A	Neutral	0.005
MEN1	O00255-1.4	G508C	Neutral	0.066
MEN1	O00255-1.4	G508D	Neutral	0.06
MEN1	O00255-1.4	G508E	Neutral	0.174
MEN1	O00255-1.4	G508F	Pathogenic	0.91
MEN1	O00255-1.4	G508H	Neutral	0.154
MEN1	O00255-1.4	G508I	Pathogenic	0.829
MEN1	O00255-1.4	G508K	Pathogenic	0.723
MEN1	O00255-1.4	G508L	Pathogenic	0.804
MEN1	O00255-1.4	G508M	Pathogenic	0.643
MEN1	O00255-1.4	G508N	Neutral	0.063
MEN1	O00255-1.4	G508P	Neutral	0.055
MEN1	O00255-1.4	G508Q	Neutral	0.135
MEN1	O00255-1.4	G508R	Pathogenic	0.876
MEN1	O00255-1.4	G508S	Neutral	0.005
MEN1	O00255-1.4	G508T	Neutral	0.033
MEN1	O00255-1.4	G508V	Neutral	0.298
MEN1	O00255-1.4	G508W	Pathogenic	0.994
MEN1	O00255-1.4	G508Y	Pathogenic	0.805
MEN1	O00255-1.4	L509A	Neutral	0.004
MEN1	O00255-1.4	L509C	Neutral	0.0
MEN1	O00255-1.4	L509D	Neutral	0.004
MEN1	O00255-1.4	L509E	Neutral	0.001
MEN1	O00255-1.4	L509F	Neutral	0.0
MEN1	O00255-1.4	L509G	Neutral	0.029
MEN1	O00255-1.4	L509H	Neutral	0.0
MEN1	O00255-1.4	L509I	Neutral	0.0
MEN1	O00255-1.4	L509K	Neutral	0.001
MEN1	O00255-1.4	L509M	Neutral	0.0
MEN1	O00255-1.4	L509N	Neutral	0.002
MEN1	O00255-1.4	L509P	Neutral	0.0
MEN1	O00255-1.4	L509Q	Neutral	0.0
MEN1	O00255-1.4	L509R	Neutral	0.003
MEN1	O00255-1.4	L509S	Neutral	0.004
MEN1	O00255-1.4	L509T	Neutral	0.001
MEN1	O00255-1.4	L509V	Neutral	0.0
MEN1	O00255-1.4	L509W	Neutral	0.0
MEN1	O00255-1.4	L509Y	Neutral	0.0
MEN1	O00255-1.4	G510A	Neutral	0.006
MEN1	O00255-1.4	G510C	Neutral	0.088
MEN1	O00255-1.4	G510D	Neutral	0.081
MEN1	O00255-1.4	G510E	Neutral	0.225
MEN1	O00255-1.4	G510F	Pathogenic	0.933
MEN1	O00255-1.4	G510H	Neutral	0.2
MEN1	O00255-1.4	G510I	Pathogenic	0.869
MEN1	O00255-1.4	G510K	Pathogenic	0.781
MEN1	O00255-1.4	G510L	Pathogenic	0.849
MEN1	O00255-1.4	G510M	Pathogenic	0.712
MEN1	O00255-1.4	G510N	Neutral	0.084
MEN1	O00255-1.4	G510P	Neutral	0.074
MEN1	O00255-1.4	G510Q	Neutral	0.176
MEN1	O00255-1.4	G510R	Pathogenic	0.906
MEN1	O00255-1.4	G510S	Neutral	0.007
MEN1	O00255-1.4	G510T	Neutral	0.045
MEN1	O00255-1.4	G510V	Neutral	0.369
MEN1	O00255-1.4	G510W	Pathogenic	0.996
MEN1	O00255-1.4	G510Y	Pathogenic	0.85
MEN1	O00255-1.4	T511A	Neutral	0.0
MEN1	O00255-1.4	T511C	Neutral	0.0
MEN1	O00255-1.4	T511D	Neutral	0.0
MEN1	O00255-1.4	T511E	Neutral	0.0
MEN1	O00255-1.4	T511F	Neutral	0.001
MEN1	O00255-1.4	T511G	Neutral	0.0
MEN1	O00255-1.4	T511H	Neutral	0.0
MEN1	O00255-1.4	T511I	Neutral	0.0
MEN1	O00255-1.4	T511K	Neutral	0.0
MEN1	O00255-1.4	T511L	Neutral	0.0
MEN1	O00255-1.4	T511M	Neutral	0.0
MEN1	O00255-1.4	T511N	Neutral	0.0
MEN1	O00255-1.4	T511P	Neutral	0.0
MEN1	O00255-1.4	T511Q	Neutral	0.0
MEN1	O00255-1.4	T511R	Neutral	0.001
MEN1	O00255-1.4	T511S	Neutral	0.0
MEN1	O00255-1.4	T511V	Neutral	0.0
MEN1	O00255-1.4	T511W	Neutral	0.013
MEN1	O00255-1.4	T511Y	Neutral	0.0
MEN1	O00255-1.4	G512A	Neutral	0.034
MEN1	O00255-1.4	G512C	Neutral	0.343
MEN1	O00255-1.4	G512D	Neutral	0.323
MEN1	O00255-1.4	G512E	Pathogenic	0.611
MEN1	O00255-1.4	G512F	Pathogenic	0.987
MEN1	O00255-1.4	G512H	Pathogenic	0.575
MEN1	O00255-1.4	G512I	Pathogenic	0.973
MEN1	O00255-1.4	G512K	Pathogenic	0.951
MEN1	O00255-1.4	G512L	Pathogenic	0.968
MEN1	O00255-1.4	G512M	Pathogenic	0.93
MEN1	O00255-1.4	G512N	Neutral	0.332
MEN1	O00255-1.4	G512P	Neutral	0.302
MEN1	O00255-1.4	G512Q	Pathogenic	0.536
MEN1	O00255-1.4	G512R	Pathogenic	0.981
MEN1	O00255-1.4	G512S	Neutral	0.034
MEN1	O00255-1.4	G512T	Neutral	0.204
MEN1	O00255-1.4	G512V	Pathogenic	0.76
MEN1	O00255-1.4	G512W	Pathogenic	0.999
MEN1	O00255-1.4	G512Y	Pathogenic	0.968
MEN1	O00255-1.4	Q513A	Neutral	0.086
MEN1	O00255-1.4	Q513C	Neutral	0.071
MEN1	O00255-1.4	Q513D	Neutral	0.015
MEN1	O00255-1.4	Q513E	Neutral	0.003
MEN1	O00255-1.4	Q513F	Neutral	0.144
MEN1	O00255-1.4	Q513G	Neutral	0.2
MEN1	O00255-1.4	Q513H	Neutral	0.003
MEN1	O00255-1.4	Q513I	Neutral	0.07
MEN1	O00255-1.4	Q513K	Neutral	0.017
MEN1	O00255-1.4	Q513L	Neutral	0.057
MEN1	O00255-1.4	Q513M	Neutral	0.024
MEN1	O00255-1.4	Q513N	Neutral	0.008
MEN1	O00255-1.4	Q513P	Neutral	0.032
MEN1	O00255-1.4	Q513R	Neutral	0.046
MEN1	O00255-1.4	Q513S	Neutral	0.031
MEN1	O00255-1.4	Q513T	Neutral	0.012
MEN1	O00255-1.4	Q513V	Neutral	0.025
MEN1	O00255-1.4	Q513W	Pathogenic	0.73
MEN1	O00255-1.4	Q513Y	Neutral	0.057
MEN1	O00255-1.4	G514A	Neutral	0.002
MEN1	O00255-1.4	G514C	Neutral	0.028
MEN1	O00255-1.4	G514D	Neutral	0.026
MEN1	O00255-1.4	G514E	Neutral	0.08
MEN1	O00255-1.4	G514F	Pathogenic	0.806
MEN1	O00255-1.4	G514H	Neutral	0.069
MEN1	O00255-1.4	G514I	Pathogenic	0.665
MEN1	O00255-1.4	G514K	Pathogenic	0.516
MEN1	O00255-1.4	G514L	Pathogenic	0.627
MEN1	O00255-1.4	G514M	Neutral	0.425
MEN1	O00255-1.4	G514N	Neutral	0.027
MEN1	O00255-1.4	G514P	Neutral	0.023
MEN1	O00255-1.4	G514Q	Neutral	0.06
MEN1	O00255-1.4	G514R	Pathogenic	0.743
MEN1	O00255-1.4	G514S	Neutral	0.002
MEN1	O00255-1.4	G514T	Neutral	0.014
MEN1	O00255-1.4	G514V	Neutral	0.148
MEN1	O00255-1.4	G514W	Pathogenic	0.985
MEN1	O00255-1.4	G514Y	Pathogenic	0.629
MEN1	O00255-1.4	A515C	Neutral	0.001
MEN1	O00255-1.4	A515D	Neutral	0.003
MEN1	O00255-1.4	A515E	Neutral	0.007
MEN1	O00255-1.4	A515F	Neutral	0.117
MEN1	O00255-1.4	A515G	Neutral	0.0
MEN1	O00255-1.4	A515H	Neutral	0.004
MEN1	O00255-1.4	A515I	Neutral	0.053
MEN1	O00255-1.4	A515K	Neutral	0.085
MEN1	O00255-1.4	A515L	Neutral	0.045
MEN1	O00255-1.4	A515M	Neutral	0.022
MEN1	O00255-1.4	A515N	Neutral	0.003
MEN1	O00255-1.4	A515P	Neutral	0.001
MEN1	O00255-1.4	A515Q	Neutral	0.006
MEN1	O00255-1.4	A515R	Neutral	0.2
MEN1	O00255-1.4	A515S	Neutral	0.0
MEN1	O00255-1.4	A515T	Neutral	0.001
MEN1	O00255-1.4	A515V	Neutral	0.005
MEN1	O00255-1.4	A515W	Pathogenic	0.707
MEN1	O00255-1.4	A515Y	Neutral	0.051
MEN1	O00255-1.4	V516A	Neutral	0.004
MEN1	O00255-1.4	V516C	Neutral	0.0
MEN1	O00255-1.4	V516D	Neutral	0.004
MEN1	O00255-1.4	V516E	Neutral	0.001
MEN1	O00255-1.4	V516F	Neutral	0.001
MEN1	O00255-1.4	V516G	Neutral	0.029
MEN1	O00255-1.4	V516H	Neutral	0.001
MEN1	O00255-1.4	V516I	Neutral	0.0
MEN1	O00255-1.4	V516K	Neutral	0.018
MEN1	O00255-1.4	V516L	Neutral	0.0
MEN1	O00255-1.4	V516M	Neutral	0.0
MEN1	O00255-1.4	V516N	Neutral	0.002
MEN1	O00255-1.4	V516P	Neutral	0.0
MEN1	O00255-1.4	V516Q	Neutral	0.001
MEN1	O00255-1.4	V516R	Neutral	0.05
MEN1	O00255-1.4	V516S	Neutral	0.005
MEN1	O00255-1.4	V516T	Neutral	0.001
MEN1	O00255-1.4	V516W	Neutral	0.023
MEN1	O00255-1.4	V516Y	Neutral	0.001
MEN1	O00255-1.4	S517A	Neutral	0.0
MEN1	O00255-1.4	S517C	Neutral	0.001
MEN1	O00255-1.4	S517D	Neutral	0.001
MEN1	O00255-1.4	S517E	Neutral	0.004
MEN1	O00255-1.4	S517F	Neutral	0.171
MEN1	O00255-1.4	S517G	Neutral	0.001
MEN1	O00255-1.4	S517H	Neutral	0.004
MEN1	O00255-1.4	S517I	Neutral	0.085
MEN1	O00255-1.4	S517K	Neutral	0.043
MEN1	O00255-1.4	S517L	Neutral	0.073
MEN1	O00255-1.4	S517M	Neutral	0.034
MEN1	O00255-1.4	S517N	Neutral	0.001
MEN1	O00255-1.4	S517P	Neutral	0.001
MEN1	O00255-1.4	S517Q	Neutral	0.003
MEN1	O00255-1.4	S517R	Neutral	0.113
MEN1	O00255-1.4	S517T	Neutral	0.001
MEN1	O00255-1.4	S517V	Neutral	0.009
MEN1	O00255-1.4	S517W	Pathogenic	0.79
MEN1	O00255-1.4	S517Y	Neutral	0.078
MEN1	O00255-1.4	G518A	Neutral	0.089
MEN1	O00255-1.4	G518C	Pathogenic	0.592
MEN1	O00255-1.4	G518D	Pathogenic	0.569
MEN1	O00255-1.4	G518E	Pathogenic	0.813
MEN1	O00255-1.4	G518F	Pathogenic	0.995
MEN1	O00255-1.4	G518H	Pathogenic	0.789
MEN1	O00255-1.4	G518I	Pathogenic	0.99
MEN1	O00255-1.4	G518K	Pathogenic	0.982
MEN1	O00255-1.4	G518L	Pathogenic	0.988
MEN1	O00255-1.4	G518M	Pathogenic	0.974
MEN1	O00255-1.4	G518N	Pathogenic	0.579
MEN1	O00255-1.4	G518P	Pathogenic	0.545
MEN1	O00255-1.4	G518Q	Pathogenic	0.762
MEN1	O00255-1.4	G518R	Pathogenic	0.993
MEN1	O00255-1.4	G518S	Neutral	0.09
MEN1	O00255-1.4	G518T	Neutral	0.415
MEN1	O00255-1.4	G518V	Pathogenic	0.898
MEN1	O00255-1.4	G518W	Pathogenic	1.0
MEN1	O00255-1.4	G518Y	Pathogenic	0.988
MEN1	O00255-1.4	P519A	Neutral	0.042
MEN1	O00255-1.4	P519C	Neutral	0.009
MEN1	O00255-1.4	P519D	Neutral	0.046
MEN1	O00255-1.4	P519E	Neutral	0.13
MEN1	O00255-1.4	P519F	Neutral	0.441
MEN1	O00255-1.4	P519G	Neutral	0.24
MEN1	O00255-1.4	P519H	Neutral	0.082
MEN1	O00255-1.4	P519I	Neutral	0.25
MEN1	O00255-1.4	P519K	Pathogenic	0.649
MEN1	O00255-1.4	P519L	Neutral	0.22
MEN1	O00255-1.4	P519M	Neutral	0.111
MEN1	O00255-1.4	P519N	Neutral	0.054
MEN1	O00255-1.4	P519Q	Neutral	0.1
MEN1	O00255-1.4	P519R	Pathogenic	0.842
MEN1	O00255-1.4	P519S	Neutral	0.046
MEN1	O00255-1.4	P519T	Neutral	0.011
MEN1	O00255-1.4	P519V	Neutral	0.029
MEN1	O00255-1.4	P519W	Pathogenic	0.931
MEN1	O00255-1.4	P519Y	Neutral	0.233
MEN1	O00255-1.4	P520A	Neutral	0.015
MEN1	O00255-1.4	P520C	Neutral	0.003
MEN1	O00255-1.4	P520D	Neutral	0.017
MEN1	O00255-1.4	P520E	Neutral	0.05
MEN1	O00255-1.4	P520F	Neutral	0.216
MEN1	O00255-1.4	P520G	Neutral	0.099
MEN1	O00255-1.4	P520H	Neutral	0.03
MEN1	O00255-1.4	P520I	Neutral	0.104
MEN1	O00255-1.4	P520K	Neutral	0.392
MEN1	O00255-1.4	P520L	Neutral	0.09
MEN1	O00255-1.4	P520M	Neutral	0.042
MEN1	O00255-1.4	P520N	Neutral	0.019
MEN1	O00255-1.4	P520Q	Neutral	0.037
MEN1	O00255-1.4	P520R	Pathogenic	0.65
MEN1	O00255-1.4	P520S	Neutral	0.017
MEN1	O00255-1.4	P520T	Neutral	0.004
MEN1	O00255-1.4	P520V	Neutral	0.01
MEN1	O00255-1.4	P520W	Pathogenic	0.825
MEN1	O00255-1.4	P520Y	Neutral	0.096
MEN1	O00255-1.4	R521A	Pathogenic	0.81
MEN1	O00255-1.4	R521C	Pathogenic	0.776
MEN1	O00255-1.4	R521D	Neutral	0.116
MEN1	O00255-1.4	R521E	Neutral	0.036
MEN1	O00255-1.4	R521F	Neutral	0.248
MEN1	O00255-1.4	R521G	Pathogenic	0.919
MEN1	O00255-1.4	R521H	Neutral	0.063
MEN1	O00255-1.4	R521I	Neutral	0.435
MEN1	O00255-1.4	R521K	Neutral	0.003
MEN1	O00255-1.4	R521L	Neutral	0.38
MEN1	O00255-1.4	R521M	Neutral	0.212
MEN1	O00255-1.4	R521N	Neutral	0.095
MEN1	O00255-1.4	R521P	Pathogenic	0.612
MEN1	O00255-1.4	R521Q	Neutral	0.046
MEN1	O00255-1.4	R521S	Pathogenic	0.609
MEN1	O00255-1.4	R521T	Neutral	0.36
MEN1	O00255-1.4	R521V	Pathogenic	0.551
MEN1	O00255-1.4	R521W	Neutral	0.448
MEN1	O00255-1.4	R521Y	Neutral	0.049
MEN1	O00255-1.4	K522A	Neutral	0.342
MEN1	O00255-1.4	K522C	Neutral	0.298
MEN1	O00255-1.4	K522D	Neutral	0.015
MEN1	O00255-1.4	K522E	Neutral	0.004
MEN1	O00255-1.4	K522F	Neutral	0.039
MEN1	O00255-1.4	K522G	Pathogenic	0.581
MEN1	O00255-1.4	K522H	Neutral	0.009
MEN1	O00255-1.4	K522I	Neutral	0.086
MEN1	O00255-1.4	K522L	Neutral	0.07
MEN1	O00255-1.4	K522M	Neutral	0.032
MEN1	O00255-1.4	K522N	Neutral	0.013
MEN1	O00255-1.4	K522P	Neutral	0.154
MEN1	O00255-1.4	K522Q	Neutral	0.006
MEN1	O00255-1.4	K522R	Neutral	0.001
MEN1	O00255-1.4	K522S	Neutral	0.152
MEN1	O00255-1.4	K522T	Neutral	0.064
MEN1	O00255-1.4	K522V	Neutral	0.124
MEN1	O00255-1.4	K522W	Neutral	0.409
MEN1	O00255-1.4	K522Y	Neutral	0.015
MEN1	O00255-1.4	P523A	Neutral	0.006
MEN1	O00255-1.4	P523C	Neutral	0.001
MEN1	O00255-1.4	P523D	Neutral	0.006
MEN1	O00255-1.4	P523E	Neutral	0.019
MEN1	O00255-1.4	P523F	Neutral	0.092
MEN1	O00255-1.4	P523G	Neutral	0.039
MEN1	O00255-1.4	P523H	Neutral	0.011
MEN1	O00255-1.4	P523I	Neutral	0.041
MEN1	O00255-1.4	P523K	Neutral	0.192
MEN1	O00255-1.4	P523L	Neutral	0.035
MEN1	O00255-1.4	P523M	Neutral	0.016
MEN1	O00255-1.4	P523N	Neutral	0.007
MEN1	O00255-1.4	P523Q	Neutral	0.014
MEN1	O00255-1.4	P523R	Neutral	0.405
MEN1	O00255-1.4	P523S	Neutral	0.006
MEN1	O00255-1.4	P523T	Neutral	0.001
MEN1	O00255-1.4	P523V	Neutral	0.004
MEN1	O00255-1.4	P523W	Pathogenic	0.634
MEN1	O00255-1.4	P523Y	Neutral	0.037
MEN1	O00255-1.4	P524A	Neutral	0.004
MEN1	O00255-1.4	P524C	Neutral	0.001
MEN1	O00255-1.4	P524D	Neutral	0.004
MEN1	O00255-1.4	P524E	Neutral	0.013
MEN1	O00255-1.4	P524F	Neutral	0.067
MEN1	O00255-1.4	P524G	Neutral	0.028
MEN1	O00255-1.4	P524H	Neutral	0.008
MEN1	O00255-1.4	P524I	Neutral	0.029
MEN1	O00255-1.4	P524K	Neutral	0.144
MEN1	O00255-1.4	P524L	Neutral	0.025
MEN1	O00255-1.4	P524M	Neutral	0.011
MEN1	O00255-1.4	P524N	Neutral	0.005
MEN1	O00255-1.4	P524Q	Neutral	0.01
MEN1	O00255-1.4	P524R	Neutral	0.326
MEN1	O00255-1.4	P524S	Neutral	0.004
MEN1	O00255-1.4	P524T	Neutral	0.001
MEN1	O00255-1.4	P524V	Neutral	0.003
MEN1	O00255-1.4	P524W	Pathogenic	0.551
MEN1	O00255-1.4	P524Y	Neutral	0.027
MEN1	O00255-1.4	G525A	Neutral	0.008
MEN1	O00255-1.4	G525C	Neutral	0.11
MEN1	O00255-1.4	G525D	Neutral	0.101
MEN1	O00255-1.4	G525E	Neutral	0.27
MEN1	O00255-1.4	G525F	Pathogenic	0.947
MEN1	O00255-1.4	G525H	Neutral	0.242
MEN1	O00255-1.4	G525I	Pathogenic	0.894
MEN1	O00255-1.4	G525K	Pathogenic	0.82
MEN1	O00255-1.4	G525L	Pathogenic	0.878
MEN1	O00255-1.4	G525M	Pathogenic	0.759
MEN1	O00255-1.4	G525N	Neutral	0.105
MEN1	O00255-1.4	G525P	Neutral	0.093
MEN1	O00255-1.4	G525Q	Neutral	0.214
MEN1	O00255-1.4	G525R	Pathogenic	0.925
MEN1	O00255-1.4	G525S	Neutral	0.008
MEN1	O00255-1.4	G525T	Neutral	0.057
MEN1	O00255-1.4	G525V	Neutral	0.427
MEN1	O00255-1.4	G525W	Pathogenic	0.997
MEN1	O00255-1.4	G525Y	Pathogenic	0.879
MEN1	O00255-1.4	T526A	Neutral	0.002
MEN1	O00255-1.4	T526C	Neutral	0.002
MEN1	O00255-1.4	T526D	Neutral	0.002
MEN1	O00255-1.4	T526E	Neutral	0.005
MEN1	O00255-1.4	T526F	Neutral	0.092
MEN1	O00255-1.4	T526G	Neutral	0.016
MEN1	O00255-1.4	T526H	Neutral	0.003
MEN1	O00255-1.4	T526I	Neutral	0.041
MEN1	O00255-1.4	T526K	Neutral	0.057
MEN1	O00255-1.4	T526L	Neutral	0.035
MEN1	O00255-1.4	T526M	Neutral	0.017
MEN1	O00255-1.4	T526N	Neutral	0.002
MEN1	O00255-1.4	T526P	Neutral	0.001
MEN1	O00255-1.4	T526Q	Neutral	0.004
MEN1	O00255-1.4	T526R	Neutral	0.14
MEN1	O00255-1.4	T526S	Neutral	0.002
MEN1	O00255-1.4	T526V	Neutral	0.004
MEN1	O00255-1.4	T526W	Pathogenic	0.635
MEN1	O00255-1.4	T526Y	Neutral	0.04
MEN1	O00255-1.4	V527A	Neutral	0.032
MEN1	O00255-1.4	V527C	Neutral	0.003
MEN1	O00255-1.4	V527D	Neutral	0.036
MEN1	O00255-1.4	V527E	Neutral	0.013
MEN1	O00255-1.4	V527F	Neutral	0.011
MEN1	O00255-1.4	V527G	Neutral	0.211
MEN1	O00255-1.4	V527H	Neutral	0.008
MEN1	O00255-1.4	V527I	Neutral	0.004
MEN1	O00255-1.4	V527K	Neutral	0.143
MEN1	O00255-1.4	V527L	Neutral	0.004
MEN1	O00255-1.4	V527M	Neutral	0.002
MEN1	O00255-1.4	V527N	Neutral	0.019
MEN1	O00255-1.4	V527P	Neutral	0.003
MEN1	O00255-1.4	V527Q	Neutral	0.01
MEN1	O00255-1.4	V527R	Neutral	0.324
MEN1	O00255-1.4	V527S	Neutral	0.04
MEN1	O00255-1.4	V527T	Neutral	0.005
MEN1	O00255-1.4	V527W	Neutral	0.176
MEN1	O00255-1.4	V527Y	Neutral	0.01
MEN1	O00255-1.4	A528C	Neutral	0.0
MEN1	O00255-1.4	A528D	Neutral	0.0
MEN1	O00255-1.4	A528E	Neutral	0.0
MEN1	O00255-1.4	A528F	Neutral	0.005
MEN1	O00255-1.4	A528G	Neutral	0.0
MEN1	O00255-1.4	A528H	Neutral	0.0
MEN1	O00255-1.4	A528I	Neutral	0.002
MEN1	O00255-1.4	A528K	Neutral	0.004
MEN1	O00255-1.4	A528L	Neutral	0.002
MEN1	O00255-1.4	A528M	Neutral	0.001
MEN1	O00255-1.4	A528N	Neutral	0.0
MEN1	O00255-1.4	A528P	Neutral	0.0
MEN1	O00255-1.4	A528Q	Neutral	0.0
MEN1	O00255-1.4	A528R	Neutral	0.01
MEN1	O00255-1.4	A528S	Neutral	0.0
MEN1	O00255-1.4	A528T	Neutral	0.0
MEN1	O00255-1.4	A528V	Neutral	0.0
MEN1	O00255-1.4	A528W	Neutral	0.087
MEN1	O00255-1.4	A528Y	Neutral	0.002
MEN1	O00255-1.4	G529A	Neutral	0.014
MEN1	O00255-1.4	G529C	Neutral	0.175
MEN1	O00255-1.4	G529D	Neutral	0.162
MEN1	O00255-1.4	G529E	Neutral	0.389
MEN1	O00255-1.4	G529F	Pathogenic	0.968
MEN1	O00255-1.4	G529H	Neutral	0.355
MEN1	O00255-1.4	G529I	Pathogenic	0.936
MEN1	O00255-1.4	G529K	Pathogenic	0.887
MEN1	O00255-1.4	G529L	Pathogenic	0.925
MEN1	O00255-1.4	G529M	Pathogenic	0.845
MEN1	O00255-1.4	G529N	Neutral	0.168
MEN1	O00255-1.4	G529P	Neutral	0.15
MEN1	O00255-1.4	G529Q	Neutral	0.32
MEN1	O00255-1.4	G529R	Pathogenic	0.955
MEN1	O00255-1.4	G529S	Neutral	0.014
MEN1	O00255-1.4	G529T	Neutral	0.094
MEN1	O00255-1.4	G529V	Pathogenic	0.562
MEN1	O00255-1.4	G529W	Pathogenic	0.998
MEN1	O00255-1.4	G529Y	Pathogenic	0.926
MEN1	O00255-1.4	T530A	Neutral	0.004
MEN1	O00255-1.4	T530C	Neutral	0.003
MEN1	O00255-1.4	T530D	Neutral	0.003
MEN1	O00255-1.4	T530E	Neutral	0.008
MEN1	O00255-1.4	T530F	Neutral	0.14
MEN1	O00255-1.4	T530G	Neutral	0.025
MEN1	O00255-1.4	T530H	Neutral	0.005
MEN1	O00255-1.4	T530I	Neutral	0.064
MEN1	O00255-1.4	T530K	Neutral	0.088
MEN1	O00255-1.4	T530L	Neutral	0.055
MEN1	O00255-1.4	T530M	Neutral	0.027
MEN1	O00255-1.4	T530N	Neutral	0.003
MEN1	O00255-1.4	T530P	Neutral	0.001
MEN1	O00255-1.4	T530Q	Neutral	0.006
MEN1	O00255-1.4	T530R	Neutral	0.207
MEN1	O00255-1.4	T530S	Neutral	0.004
MEN1	O00255-1.4	T530V	Neutral	0.006
MEN1	O00255-1.4	T530W	Pathogenic	0.736
MEN1	O00255-1.4	T530Y	Neutral	0.062
MEN1	O00255-1.4	A531C	Neutral	0.0
MEN1	O00255-1.4	A531D	Neutral	0.001
MEN1	O00255-1.4	A531E	Neutral	0.003
MEN1	O00255-1.4	A531F	Neutral	0.058
MEN1	O00255-1.4	A531G	Neutral	0.0
MEN1	O00255-1.4	A531H	Neutral	0.002
MEN1	O00255-1.4	A531I	Neutral	0.025
MEN1	O00255-1.4	A531K	Neutral	0.041
MEN1	O00255-1.4	A531L	Neutral	0.022
MEN1	O00255-1.4	A531M	Neutral	0.01
MEN1	O00255-1.4	A531N	Neutral	0.001
MEN1	O00255-1.4	A531P	Neutral	0.0
MEN1	O00255-1.4	A531Q	Neutral	0.003
MEN1	O00255-1.4	A531R	Neutral	0.104
MEN1	O00255-1.4	A531S	Neutral	0.0
MEN1	O00255-1.4	A531T	Neutral	0.0
MEN1	O00255-1.4	A531V	Neutral	0.002
MEN1	O00255-1.4	A531W	Pathogenic	0.528
MEN1	O00255-1.4	A531Y	Neutral	0.025
MEN1	O00255-1.4	R532A	Pathogenic	0.743
MEN1	O00255-1.4	R532C	Pathogenic	0.701
MEN1	O00255-1.4	R532D	Neutral	0.082
MEN1	O00255-1.4	R532E	Neutral	0.025
MEN1	O00255-1.4	R532F	Neutral	0.183
MEN1	O00255-1.4	R532G	Pathogenic	0.885
MEN1	O00255-1.4	R532H	Neutral	0.043
MEN1	O00255-1.4	R532I	Neutral	0.343
MEN1	O00255-1.4	R532K	Neutral	0.002
MEN1	O00255-1.4	R532L	Neutral	0.293
MEN1	O00255-1.4	R532M	Neutral	0.154
MEN1	O00255-1.4	R532N	Neutral	0.067
MEN1	O00255-1.4	R532P	Pathogenic	0.517
MEN1	O00255-1.4	R532Q	Neutral	0.031
MEN1	O00255-1.4	R532S	Pathogenic	0.513
MEN1	O00255-1.4	R532T	Neutral	0.276
MEN1	O00255-1.4	R532V	Neutral	0.454
MEN1	O00255-1.4	R532W	Neutral	0.355
MEN1	O00255-1.4	R532Y	Neutral	0.034
MEN1	O00255-1.4	G533A	Neutral	0.004
MEN1	O00255-1.4	G533C	Neutral	0.052
MEN1	O00255-1.4	G533D	Neutral	0.048
MEN1	O00255-1.4	G533E	Neutral	0.142
MEN1	O00255-1.4	G533F	Pathogenic	0.888
MEN1	O00255-1.4	G533H	Neutral	0.125
MEN1	O00255-1.4	G533I	Pathogenic	0.791
MEN1	O00255-1.4	G533K	Pathogenic	0.671
MEN1	O00255-1.4	G533L	Pathogenic	0.762
MEN1	O00255-1.4	G533M	Pathogenic	0.585
MEN1	O00255-1.4	G533N	Neutral	0.05
MEN1	O00255-1.4	G533P	Neutral	0.044
MEN1	O00255-1.4	G533Q	Neutral	0.109
MEN1	O00255-1.4	G533R	Pathogenic	0.847
MEN1	O00255-1.4	G533S	Neutral	0.004
MEN1	O00255-1.4	G533T	Neutral	0.026
MEN1	O00255-1.4	G533V	Neutral	0.25
MEN1	O00255-1.4	G533W	Pathogenic	0.992
MEN1	O00255-1.4	G533Y	Pathogenic	0.764
MEN1	O00255-1.4	P534A	Neutral	0.023
MEN1	O00255-1.4	P534C	Neutral	0.005
MEN1	O00255-1.4	P534D	Neutral	0.026
MEN1	O00255-1.4	P534E	Neutral	0.075
MEN1	O00255-1.4	P534F	Neutral	0.299
MEN1	O00255-1.4	P534G	Neutral	0.146
MEN1	O00255-1.4	P534H	Neutral	0.046
MEN1	O00255-1.4	P534I	Neutral	0.153
MEN1	O00255-1.4	P534K	Pathogenic	0.5
MEN1	O00255-1.4	P534L	Neutral	0.133
MEN1	O00255-1.4	P534M	Neutral	0.063
MEN1	O00255-1.4	P534N	Neutral	0.03
MEN1	O00255-1.4	P534Q	Neutral	0.056
MEN1	O00255-1.4	P534R	Pathogenic	0.742
MEN1	O00255-1.4	P534S	Neutral	0.026
MEN1	O00255-1.4	P534T	Neutral	0.006
MEN1	O00255-1.4	P534V	Neutral	0.016
MEN1	O00255-1.4	P534W	Pathogenic	0.88
MEN1	O00255-1.4	P534Y	Neutral	0.141
MEN1	O00255-1.4	E535A	Neutral	0.082
MEN1	O00255-1.4	E535C	Neutral	0.071
MEN1	O00255-1.4	E535D	Neutral	0.003
MEN1	O00255-1.4	E535F	Neutral	0.251
MEN1	O00255-1.4	E535G	Neutral	0.192
MEN1	O00255-1.4	E535H	Neutral	0.005
MEN1	O00255-1.4	E535I	Neutral	0.131
MEN1	O00255-1.4	E535K	Neutral	0.009
MEN1	O00255-1.4	E535L	Neutral	0.113
MEN1	O00255-1.4	E535M	Neutral	0.053
MEN1	O00255-1.4	E535N	Neutral	0.002
MEN1	O00255-1.4	E535P	Neutral	0.03
MEN1	O00255-1.4	E535Q	Neutral	0.002
MEN1	O00255-1.4	E535R	Neutral	0.025
MEN1	O00255-1.4	E535S	Neutral	0.03
MEN1	O00255-1.4	E535T	Neutral	0.012
MEN1	O00255-1.4	E535V	Neutral	0.024
MEN1	O00255-1.4	E535W	Pathogenic	0.852
MEN1	O00255-1.4	E535Y	Neutral	0.114
MEN1	O00255-1.4	G536A	Neutral	0.001
MEN1	O00255-1.4	G536C	Neutral	0.009
MEN1	O00255-1.4	G536D	Neutral	0.008
MEN1	O00255-1.4	G536E	Neutral	0.027
MEN1	O00255-1.4	G536F	Pathogenic	0.572
MEN1	O00255-1.4	G536H	Neutral	0.023
MEN1	O00255-1.4	G536I	Neutral	0.39
MEN1	O00255-1.4	G536K	Neutral	0.256
MEN1	O00255-1.4	G536L	Neutral	0.351
MEN1	O00255-1.4	G536M	Neutral	0.192
MEN1	O00255-1.4	G536N	Neutral	0.009
MEN1	O00255-1.4	G536P	Neutral	0.008
MEN1	O00255-1.4	G536Q	Neutral	0.02
MEN1	O00255-1.4	G536R	Neutral	0.482
MEN1	O00255-1.4	G536S	Neutral	0.001
MEN1	O00255-1.4	G536T	Neutral	0.005
MEN1	O00255-1.4	G536V	Neutral	0.053
MEN1	O00255-1.4	G536W	Pathogenic	0.956
MEN1	O00255-1.4	G536Y	Neutral	0.353
MEN1	O00255-1.4	G537A	Neutral	0.001
MEN1	O00255-1.4	G537C	Neutral	0.013
MEN1	O00255-1.4	G537D	Neutral	0.011
MEN1	O00255-1.4	G537E	Neutral	0.037
MEN1	O00255-1.4	G537F	Pathogenic	0.646
MEN1	O00255-1.4	G537H	Neutral	0.032
MEN1	O00255-1.4	G537I	Neutral	0.466
MEN1	O00255-1.4	G537K	Neutral	0.319
MEN1	O00255-1.4	G537L	Neutral	0.425
MEN1	O00255-1.4	G537M	Neutral	0.245
MEN1	O00255-1.4	G537N	Neutral	0.012
MEN1	O00255-1.4	G537P	Neutral	0.01
MEN1	O00255-1.4	G537Q	Neutral	0.027
MEN1	O00255-1.4	G537R	Pathogenic	0.559
MEN1	O00255-1.4	G537S	Neutral	0.001
MEN1	O00255-1.4	G537T	Neutral	0.006
MEN1	O00255-1.4	G537V	Neutral	0.071
MEN1	O00255-1.4	G537W	Pathogenic	0.967
MEN1	O00255-1.4	G537Y	Neutral	0.427
MEN1	O00255-1.4	S538A	Neutral	0.001
MEN1	O00255-1.4	S538C	Neutral	0.006
MEN1	O00255-1.4	S538D	Neutral	0.005
MEN1	O00255-1.4	S538E	Neutral	0.015
MEN1	O00255-1.4	S538F	Neutral	0.466
MEN1	O00255-1.4	S538G	Neutral	0.003
MEN1	O00255-1.4	S538H	Neutral	0.015
MEN1	O00255-1.4	S538I	Neutral	0.282
MEN1	O00255-1.4	S538K	Neutral	0.158
MEN1	O00255-1.4	S538L	Neutral	0.25
MEN1	O00255-1.4	S538M	Neutral	0.128
MEN1	O00255-1.4	S538N	Neutral	0.005
MEN1	O00255-1.4	S538P	Neutral	0.005
MEN1	O00255-1.4	S538Q	Neutral	0.011
MEN1	O00255-1.4	S538R	Neutral	0.35
MEN1	O00255-1.4	S538T	Neutral	0.003
MEN1	O00255-1.4	S538V	Neutral	0.035
MEN1	O00255-1.4	S538W	Pathogenic	0.941
MEN1	O00255-1.4	S538Y	Neutral	0.263
MEN1	O00255-1.4	T539A	Neutral	0.001
MEN1	O00255-1.4	T539C	Neutral	0.0
MEN1	O00255-1.4	T539D	Neutral	0.001
MEN1	O00255-1.4	T539E	Neutral	0.001
MEN1	O00255-1.4	T539F	Neutral	0.024
MEN1	O00255-1.4	T539G	Neutral	0.004
MEN1	O00255-1.4	T539H	Neutral	0.001
MEN1	O00255-1.4	T539I	Neutral	0.01
MEN1	O00255-1.4	T539K	Neutral	0.014
MEN1	O00255-1.4	T539L	Neutral	0.009
MEN1	O00255-1.4	T539M	Neutral	0.004
MEN1	O00255-1.4	T539N	Neutral	0.0
MEN1	O00255-1.4	T539P	Neutral	0.0
MEN1	O00255-1.4	T539Q	Neutral	0.001
MEN1	O00255-1.4	T539R	Neutral	0.038
MEN1	O00255-1.4	T539S	Neutral	0.001
MEN1	O00255-1.4	T539V	Neutral	0.001
MEN1	O00255-1.4	T539W	Neutral	0.294
MEN1	O00255-1.4	T539Y	Neutral	0.01
MEN1	O00255-1.4	A540C	Neutral	0.005
MEN1	O00255-1.4	A540D	Neutral	0.016
MEN1	O00255-1.4	A540E	Neutral	0.046
MEN1	O00255-1.4	A540F	Neutral	0.461
MEN1	O00255-1.4	A540G	Neutral	0.003
MEN1	O00255-1.4	A540H	Neutral	0.028
MEN1	O00255-1.4	A540I	Neutral	0.266
MEN1	O00255-1.4	A540K	Neutral	0.375
MEN1	O00255-1.4	A540L	Neutral	0.235
MEN1	O00255-1.4	A540M	Neutral	0.126
MEN1	O00255-1.4	A540N	Neutral	0.018
MEN1	O00255-1.4	A540P	Neutral	0.005
MEN1	O00255-1.4	A540Q	Neutral	0.035
MEN1	O00255-1.4	A540R	Pathogenic	0.618
MEN1	O00255-1.4	A540S	Neutral	0.001
MEN1	O00255-1.4	A540T	Neutral	0.003
MEN1	O00255-1.4	A540V	Neutral	0.031
MEN1	O00255-1.4	A540W	Pathogenic	0.94
MEN1	O00255-1.4	A540Y	Neutral	0.259
MEN1	O00255-1.4	Q541A	Neutral	0.013
MEN1	O00255-1.4	Q541C	Neutral	0.01
MEN1	O00255-1.4	Q541D	Neutral	0.002
MEN1	O00255-1.4	Q541E	Neutral	0.0
MEN1	O00255-1.4	Q541F	Neutral	0.022
MEN1	O00255-1.4	Q541G	Neutral	0.033
MEN1	O00255-1.4	Q541H	Neutral	0.0
MEN1	O00255-1.4	Q541I	Neutral	0.01
MEN1	O00255-1.4	Q541K	Neutral	0.002
MEN1	O00255-1.4	Q541L	Neutral	0.008
MEN1	O00255-1.4	Q541M	Neutral	0.003
MEN1	O00255-1.4	Q541N	Neutral	0.001
MEN1	O00255-1.4	Q541P	Neutral	0.004
MEN1	O00255-1.4	Q541R	Neutral	0.006
MEN1	O00255-1.4	Q541S	Neutral	0.004
MEN1	O00255-1.4	Q541T	Neutral	0.002
MEN1	O00255-1.4	Q541V	Neutral	0.003
MEN1	O00255-1.4	Q541W	Neutral	0.269
MEN1	O00255-1.4	Q541Y	Neutral	0.008
MEN1	O00255-1.4	V542A	Neutral	0.005
MEN1	O00255-1.4	V542C	Neutral	0.0
MEN1	O00255-1.4	V542D	Neutral	0.005
MEN1	O00255-1.4	V542E	Neutral	0.002
MEN1	O00255-1.4	V542F	Neutral	0.002
MEN1	O00255-1.4	V542G	Neutral	0.037
MEN1	O00255-1.4	V542H	Neutral	0.001
MEN1	O00255-1.4	V542I	Neutral	0.001
MEN1	O00255-1.4	V542K	Neutral	0.024
MEN1	O00255-1.4	V542L	Neutral	0.001
MEN1	O00255-1.4	V542M	Neutral	0.0
MEN1	O00255-1.4	V542N	Neutral	0.003
MEN1	O00255-1.4	V542P	Neutral	0.0
MEN1	O00255-1.4	V542Q	Neutral	0.001
MEN1	O00255-1.4	V542R	Neutral	0.065
MEN1	O00255-1.4	V542S	Neutral	0.006
MEN1	O00255-1.4	V542T	Neutral	0.001
MEN1	O00255-1.4	V542W	Neutral	0.03
MEN1	O00255-1.4	V542Y	Neutral	0.002
MEN1	O00255-1.4	P543A	Neutral	0.015
MEN1	O00255-1.4	P543C	Neutral	0.003
MEN1	O00255-1.4	P543D	Neutral	0.017
MEN1	O00255-1.4	P543E	Neutral	0.05
MEN1	O00255-1.4	P543F	Neutral	0.215
MEN1	O00255-1.4	P543G	Neutral	0.099
MEN1	O00255-1.4	P543H	Neutral	0.03
MEN1	O00255-1.4	P543I	Neutral	0.104
MEN1	O00255-1.4	P543K	Neutral	0.391
MEN1	O00255-1.4	P543L	Neutral	0.089
MEN1	O00255-1.4	P543M	Neutral	0.041
MEN1	O00255-1.4	P543N	Neutral	0.019
MEN1	O00255-1.4	P543Q	Neutral	0.037
MEN1	O00255-1.4	P543R	Pathogenic	0.649
MEN1	O00255-1.4	P543S	Neutral	0.017
MEN1	O00255-1.4	P543T	Neutral	0.004
MEN1	O00255-1.4	P543V	Neutral	0.01
MEN1	O00255-1.4	P543W	Pathogenic	0.824
MEN1	O00255-1.4	P543Y	Neutral	0.095
MEN1	O00255-1.4	A544C	Neutral	0.001
MEN1	O00255-1.4	A544D	Neutral	0.003
MEN1	O00255-1.4	A544E	Neutral	0.008
MEN1	O00255-1.4	A544F	Neutral	0.131
MEN1	O00255-1.4	A544G	Neutral	0.001
MEN1	O00255-1.4	A544H	Neutral	0.005
MEN1	O00255-1.4	A544I	Neutral	0.06
MEN1	O00255-1.4	A544K	Neutral	0.096
MEN1	O00255-1.4	A544L	Neutral	0.051
MEN1	O00255-1.4	A544M	Neutral	0.025
MEN1	O00255-1.4	A544N	Neutral	0.003
MEN1	O00255-1.4	A544P	Neutral	0.001
MEN1	O00255-1.4	A544Q	Neutral	0.006
MEN1	O00255-1.4	A544R	Neutral	0.222
MEN1	O00255-1.4	A544S	Neutral	0.0
MEN1	O00255-1.4	A544T	Neutral	0.001
MEN1	O00255-1.4	A544V	Neutral	0.006
MEN1	O00255-1.4	A544W	Pathogenic	0.733
MEN1	O00255-1.4	A544Y	Neutral	0.058
MEN1	O00255-1.4	P545A	Neutral	0.009
MEN1	O00255-1.4	P545C	Neutral	0.002
MEN1	O00255-1.4	P545D	Neutral	0.01
MEN1	O00255-1.4	P545E	Neutral	0.032
MEN1	O00255-1.4	P545F	Neutral	0.146
MEN1	O00255-1.4	P545G	Neutral	0.064
MEN1	O00255-1.4	P545H	Neutral	0.019
MEN1	O00255-1.4	P545I	Neutral	0.068
MEN1	O00255-1.4	P545K	Neutral	0.287
MEN1	O00255-1.4	P545L	Neutral	0.058
MEN1	O00255-1.4	P545M	Neutral	0.026
MEN1	O00255-1.4	P545N	Neutral	0.012
MEN1	O00255-1.4	P545Q	Neutral	0.024
MEN1	O00255-1.4	P545R	Pathogenic	0.536
MEN1	O00255-1.4	P545S	Neutral	0.01
MEN1	O00255-1.4	P545T	Neutral	0.002
MEN1	O00255-1.4	P545V	Neutral	0.006
MEN1	O00255-1.4	P545W	Pathogenic	0.746
MEN1	O00255-1.4	P545Y	Neutral	0.062
MEN1	O00255-1.4	T546A	Neutral	0.0
MEN1	O00255-1.4	T546C	Neutral	0.0
MEN1	O00255-1.4	T546D	Neutral	0.0
MEN1	O00255-1.4	T546E	Neutral	0.0
MEN1	O00255-1.4	T546F	Neutral	0.0
MEN1	O00255-1.4	T546G	Neutral	0.0
MEN1	O00255-1.4	T546H	Neutral	0.0
MEN1	O00255-1.4	T546I	Neutral	0.0
MEN1	O00255-1.4	T546K	Neutral	0.0
MEN1	O00255-1.4	T546L	Neutral	0.0
MEN1	O00255-1.4	T546M	Neutral	0.0
MEN1	O00255-1.4	T546N	Neutral	0.0
MEN1	O00255-1.4	T546P	Neutral	0.0
MEN1	O00255-1.4	T546Q	Neutral	0.0
MEN1	O00255-1.4	T546R	Neutral	0.0
MEN1	O00255-1.4	T546S	Neutral	0.0
MEN1	O00255-1.4	T546V	Neutral	0.0
MEN1	O00255-1.4	T546W	Neutral	0.005
MEN1	O00255-1.4	T546Y	Neutral	0.0
MEN1	O00255-1.4	A547C	Neutral	0.003
MEN1	O00255-1.4	A547D	Neutral	0.008
MEN1	O00255-1.4	A547E	Neutral	0.023
MEN1	O00255-1.4	A547F	Neutral	0.295
MEN1	O00255-1.4	A547G	Neutral	0.001
MEN1	O00255-1.4	A547H	Neutral	0.014
MEN1	O00255-1.4	A547I	Neutral	0.151
MEN1	O00255-1.4	A547K	Neutral	0.226
MEN1	O00255-1.4	A547L	Neutral	0.131
MEN1	O00255-1.4	A547M	Neutral	0.066
MEN1	O00255-1.4	A547N	Neutral	0.009
MEN1	O00255-1.4	A547P	Neutral	0.002
MEN1	O00255-1.4	A547Q	Neutral	0.017
MEN1	O00255-1.4	A547R	Neutral	0.442
MEN1	O00255-1.4	A547S	Neutral	0.001
MEN1	O00255-1.4	A547T	Neutral	0.002
MEN1	O00255-1.4	A547V	Neutral	0.015
MEN1	O00255-1.4	A547W	Pathogenic	0.884
MEN1	O00255-1.4	A547Y	Neutral	0.146
MEN1	O00255-1.4	S548A	Neutral	0.001
MEN1	O00255-1.4	S548C	Neutral	0.007
MEN1	O00255-1.4	S548D	Neutral	0.006
MEN1	O00255-1.4	S548E	Neutral	0.018
MEN1	O00255-1.4	S548F	Pathogenic	0.519
MEN1	O00255-1.4	S548G	Neutral	0.003
MEN1	O00255-1.4	S548H	Neutral	0.019
MEN1	O00255-1.4	S548I	Neutral	0.327
MEN1	O00255-1.4	S548K	Neutral	0.189
MEN1	O00255-1.4	S548L	Neutral	0.292
MEN1	O00255-1.4	S548M	Neutral	0.153
MEN1	O00255-1.4	S548N	Neutral	0.006
MEN1	O00255-1.4	S548P	Neutral	0.006
MEN1	O00255-1.4	S548Q	Neutral	0.014
MEN1	O00255-1.4	S548R	Neutral	0.4
MEN1	O00255-1.4	S548T	Neutral	0.003
MEN1	O00255-1.4	S548V	Neutral	0.043
MEN1	O00255-1.4	S548W	Pathogenic	0.952
MEN1	O00255-1.4	S548Y	Neutral	0.306
MEN1	O00255-1.4	P549A	Neutral	0.015
MEN1	O00255-1.4	P549C	Neutral	0.003
MEN1	O00255-1.4	P549D	Neutral	0.016
MEN1	O00255-1.4	P549E	Neutral	0.049
MEN1	O00255-1.4	P549F	Neutral	0.212
MEN1	O00255-1.4	P549G	Neutral	0.097
MEN1	O00255-1.4	P549H	Neutral	0.03
MEN1	O00255-1.4	P549I	Neutral	0.102
MEN1	O00255-1.4	P549K	Neutral	0.387
MEN1	O00255-1.4	P549L	Neutral	0.088
MEN1	O00255-1.4	P549M	Neutral	0.041
MEN1	O00255-1.4	P549N	Neutral	0.019
MEN1	O00255-1.4	P549Q	Neutral	0.036
MEN1	O00255-1.4	P549R	Pathogenic	0.644
MEN1	O00255-1.4	P549S	Neutral	0.016
MEN1	O00255-1.4	P549T	Neutral	0.004
MEN1	O00255-1.4	P549V	Neutral	0.01
MEN1	O00255-1.4	P549W	Pathogenic	0.821
MEN1	O00255-1.4	P549Y	Neutral	0.094
MEN1	O00255-1.4	P550A	Neutral	0.008
MEN1	O00255-1.4	P550C	Neutral	0.002
MEN1	O00255-1.4	P550D	Neutral	0.009
MEN1	O00255-1.4	P550E	Neutral	0.028
MEN1	O00255-1.4	P550F	Neutral	0.13
MEN1	O00255-1.4	P550G	Neutral	0.056
MEN1	O00255-1.4	P550H	Neutral	0.017
MEN1	O00255-1.4	P550I	Neutral	0.059
MEN1	O00255-1.4	P550K	Neutral	0.259
MEN1	O00255-1.4	P550L	Neutral	0.051
MEN1	O00255-1.4	P550M	Neutral	0.023
MEN1	O00255-1.4	P550N	Neutral	0.011
MEN1	O00255-1.4	P550Q	Neutral	0.021
MEN1	O00255-1.4	P550R	Pathogenic	0.501
MEN1	O00255-1.4	P550S	Neutral	0.009
MEN1	O00255-1.4	P550T	Neutral	0.002
MEN1	O00255-1.4	P550V	Neutral	0.006
MEN1	O00255-1.4	P550W	Pathogenic	0.719
MEN1	O00255-1.4	P550Y	Neutral	0.054
MEN1	O00255-1.4	P551A	Neutral	0.026
MEN1	O00255-1.4	P551C	Neutral	0.006
MEN1	O00255-1.4	P551D	Neutral	0.029
MEN1	O00255-1.4	P551E	Neutral	0.084
MEN1	O00255-1.4	P551F	Neutral	0.324
MEN1	O00255-1.4	P551G	Neutral	0.161
MEN1	O00255-1.4	P551H	Neutral	0.052
MEN1	O00255-1.4	P551I	Neutral	0.169
MEN1	O00255-1.4	P551K	Pathogenic	0.53
MEN1	O00255-1.4	P551L	Neutral	0.147
MEN1	O00255-1.4	P551M	Neutral	0.07
MEN1	O00255-1.4	P551N	Neutral	0.033
MEN1	O00255-1.4	P551Q	Neutral	0.063
MEN1	O00255-1.4	P551R	Pathogenic	0.764
MEN1	O00255-1.4	P551S	Neutral	0.029
MEN1	O00255-1.4	P551T	Neutral	0.006
MEN1	O00255-1.4	P551V	Neutral	0.018
MEN1	O00255-1.4	P551W	Pathogenic	0.891
MEN1	O00255-1.4	P551Y	Neutral	0.156
MEN1	O00255-1.4	E552A	Neutral	0.097
MEN1	O00255-1.4	E552C	Neutral	0.085
MEN1	O00255-1.4	E552D	Neutral	0.004
MEN1	O00255-1.4	E552F	Neutral	0.289
MEN1	O00255-1.4	E552G	Neutral	0.223
MEN1	O00255-1.4	E552H	Neutral	0.006
MEN1	O00255-1.4	E552I	Neutral	0.155
MEN1	O00255-1.4	E552K	Neutral	0.011
MEN1	O00255-1.4	E552L	Neutral	0.134
MEN1	O00255-1.4	E552M	Neutral	0.064
MEN1	O00255-1.4	E552N	Neutral	0.003
MEN1	O00255-1.4	E552P	Neutral	0.036
MEN1	O00255-1.4	E552Q	Neutral	0.002
MEN1	O00255-1.4	E552R	Neutral	0.031
MEN1	O00255-1.4	E552S	Neutral	0.036
MEN1	O00255-1.4	E552T	Neutral	0.014
MEN1	O00255-1.4	E552V	Neutral	0.028
MEN1	O00255-1.4	E552W	Pathogenic	0.874
MEN1	O00255-1.4	E552Y	Neutral	0.135
MEN1	O00255-1.4	G553A	Neutral	0.018
MEN1	O00255-1.4	G553C	Neutral	0.216
MEN1	O00255-1.4	G553D	Neutral	0.201
MEN1	O00255-1.4	G553E	Neutral	0.453
MEN1	O00255-1.4	G553F	Pathogenic	0.975
MEN1	O00255-1.4	G553H	Neutral	0.417
MEN1	O00255-1.4	G553I	Pathogenic	0.95
MEN1	O00255-1.4	G553K	Pathogenic	0.911
MEN1	O00255-1.4	G553L	Pathogenic	0.941
MEN1	O00255-1.4	G553M	Pathogenic	0.876
MEN1	O00255-1.4	G553N	Neutral	0.208
MEN1	O00255-1.4	G553P	Neutral	0.186
MEN1	O00255-1.4	G553Q	Neutral	0.379
MEN1	O00255-1.4	G553R	Pathogenic	0.965
MEN1	O00255-1.4	G553S	Neutral	0.018
MEN1	O00255-1.4	G553T	Neutral	0.119
MEN1	O00255-1.4	G553V	Pathogenic	0.625
MEN1	O00255-1.4	G553W	Pathogenic	0.998
MEN1	O00255-1.4	G553Y	Pathogenic	0.942
MEN1	O00255-1.4	P554A	Neutral	0.406
MEN1	O00255-1.4	P554C	Neutral	0.128
MEN1	O00255-1.4	P554D	Neutral	0.431
MEN1	O00255-1.4	P554E	Pathogenic	0.701
MEN1	O00255-1.4	P554F	Pathogenic	0.925
MEN1	O00255-1.4	P554G	Pathogenic	0.832
MEN1	O00255-1.4	P554H	Pathogenic	0.584
MEN1	O00255-1.4	P554I	Pathogenic	0.84
MEN1	O00255-1.4	P554K	Pathogenic	0.967
MEN1	O00255-1.4	P554L	Pathogenic	0.816
MEN1	O00255-1.4	P554M	Pathogenic	0.661
MEN1	O00255-1.4	P554N	Neutral	0.471
MEN1	O00255-1.4	P554Q	Pathogenic	0.634
MEN1	O00255-1.4	P554R	Pathogenic	0.988
MEN1	O00255-1.4	P554S	Neutral	0.433
MEN1	O00255-1.4	P554T	Neutral	0.143
MEN1	O00255-1.4	P554V	Neutral	0.315
MEN1	O00255-1.4	P554W	Pathogenic	0.995
MEN1	O00255-1.4	P554Y	Pathogenic	0.826
MEN1	O00255-1.4	V555A	Neutral	0.136
MEN1	O00255-1.4	V555C	Neutral	0.013
MEN1	O00255-1.4	V555D	Neutral	0.152
MEN1	O00255-1.4	V555E	Neutral	0.061
MEN1	O00255-1.4	V555F	Neutral	0.05
MEN1	O00255-1.4	V555G	Pathogenic	0.561
MEN1	O00255-1.4	V555H	Neutral	0.037
MEN1	O00255-1.4	V555I	Neutral	0.018
MEN1	O00255-1.4	V555K	Neutral	0.444
MEN1	O00255-1.4	V555L	Neutral	0.018
MEN1	O00255-1.4	V555M	Neutral	0.008
MEN1	O00255-1.4	V555N	Neutral	0.086
MEN1	O00255-1.4	V555P	Neutral	0.016
MEN1	O00255-1.4	V555Q	Neutral	0.046
MEN1	O00255-1.4	V555R	Pathogenic	0.696
MEN1	O00255-1.4	V555S	Neutral	0.165
MEN1	O00255-1.4	V555T	Neutral	0.024
MEN1	O00255-1.4	V555W	Pathogenic	0.506
MEN1	O00255-1.4	V555Y	Neutral	0.047
MEN1	O00255-1.4	L556A	Pathogenic	0.586
MEN1	O00255-1.4	L556C	Neutral	0.103
MEN1	O00255-1.4	L556D	Pathogenic	0.618
MEN1	O00255-1.4	L556E	Neutral	0.243
MEN1	O00255-1.4	L556F	Neutral	0.005
MEN1	O00255-1.4	L556G	Pathogenic	0.92
MEN1	O00255-1.4	L556H	Neutral	0.045
MEN1	O00255-1.4	L556I	Neutral	0.002
MEN1	O00255-1.4	L556K	Neutral	0.284
MEN1	O00255-1.4	L556M	Neutral	0.004
MEN1	O00255-1.4	L556N	Neutral	0.444
MEN1	O00255-1.4	L556P	Neutral	0.128
MEN1	O00255-1.4	L556Q	Neutral	0.096
MEN1	O00255-1.4	L556R	Pathogenic	0.518
MEN1	O00255-1.4	L556S	Pathogenic	0.627
MEN1	O00255-1.4	L556T	Neutral	0.181
MEN1	O00255-1.4	L556V	Neutral	0.017
MEN1	O00255-1.4	L556W	Neutral	0.091
MEN1	O00255-1.4	L556Y	Neutral	0.024
MEN1	O00255-1.4	T557A	Neutral	0.043
MEN1	O00255-1.4	T557C	Neutral	0.034
MEN1	O00255-1.4	T557D	Neutral	0.037
MEN1	O00255-1.4	T557E	Neutral	0.082
MEN1	O00255-1.4	T557F	Pathogenic	0.651
MEN1	O00255-1.4	T557G	Neutral	0.227
MEN1	O00255-1.4	T557H	Neutral	0.051
MEN1	O00255-1.4	T557I	Neutral	0.441
MEN1	O00255-1.4	T557K	Pathogenic	0.524
MEN1	O00255-1.4	T557L	Neutral	0.401
MEN1	O00255-1.4	T557M	Neutral	0.238
MEN1	O00255-1.4	T557N	Neutral	0.029
MEN1	O00255-1.4	T557P	Neutral	0.017
MEN1	O00255-1.4	T557Q	Neutral	0.062
MEN1	O00255-1.4	T557R	Pathogenic	0.749
MEN1	O00255-1.4	T557S	Neutral	0.039
MEN1	O00255-1.4	T557V	Neutral	0.065
MEN1	O00255-1.4	T557W	Pathogenic	0.97
MEN1	O00255-1.4	T557Y	Neutral	0.432
MEN1	O00255-1.4	F558A	Pathogenic	0.995
MEN1	O00255-1.4	F558C	Pathogenic	0.936
MEN1	O00255-1.4	F558D	Pathogenic	0.995
MEN1	O00255-1.4	F558E	Pathogenic	0.975
MEN1	O00255-1.4	F558G	Pathogenic	0.999
MEN1	O00255-1.4	F558H	Pathogenic	0.834
MEN1	O00255-1.4	F558I	Neutral	0.174
MEN1	O00255-1.4	F558K	Pathogenic	0.908
MEN1	O00255-1.4	F558L	Neutral	0.192
MEN1	O00255-1.4	F558M	Neutral	0.337
MEN1	O00255-1.4	F558N	Pathogenic	0.99
MEN1	O00255-1.4	F558P	Pathogenic	0.95
MEN1	O00255-1.4	F558Q	Pathogenic	0.931
MEN1	O00255-1.4	F558R	Pathogenic	0.964
MEN1	O00255-1.4	F558S	Pathogenic	0.995
MEN1	O00255-1.4	F558T	Pathogenic	0.966
MEN1	O00255-1.4	F558V	Pathogenic	0.696
MEN1	O00255-1.4	F558W	Pathogenic	0.594
MEN1	O00255-1.4	F558Y	Neutral	0.312
MEN1	O00255-1.4	Q559A	Neutral	0.322
MEN1	O00255-1.4	Q559C	Neutral	0.279
MEN1	O00255-1.4	Q559D	Neutral	0.072
MEN1	O00255-1.4	Q559E	Neutral	0.014
MEN1	O00255-1.4	Q559F	Neutral	0.459
MEN1	O00255-1.4	Q559G	Pathogenic	0.559
MEN1	O00255-1.4	Q559H	Neutral	0.013
MEN1	O00255-1.4	Q559I	Neutral	0.277
MEN1	O00255-1.4	Q559K	Neutral	0.082
MEN1	O00255-1.4	Q559L	Neutral	0.234
MEN1	O00255-1.4	Q559M	Neutral	0.112
MEN1	O00255-1.4	Q559N	Neutral	0.039
MEN1	O00255-1.4	Q559P	Neutral	0.142
MEN1	O00255-1.4	Q559R	Neutral	0.195
MEN1	O00255-1.4	Q559S	Neutral	0.141
MEN1	O00255-1.4	Q559T	Neutral	0.059
MEN1	O00255-1.4	Q559V	Neutral	0.114
MEN1	O00255-1.4	Q559W	Pathogenic	0.932
MEN1	O00255-1.4	Q559Y	Neutral	0.235
MEN1	O00255-1.4	S560A	Pathogenic	0.545
MEN1	O00255-1.4	S560C	Pathogenic	0.872
MEN1	O00255-1.4	S560D	Pathogenic	0.854
MEN1	O00255-1.4	S560E	Pathogenic	0.948
MEN1	O00255-1.4	S560F	Pathogenic	0.999
MEN1	O00255-1.4	S560G	Pathogenic	0.761
MEN1	O00255-1.4	S560H	Pathogenic	0.949
MEN1	O00255-1.4	S560I	Pathogenic	0.998
MEN1	O00255-1.4	S560K	Pathogenic	0.996
MEN1	O00255-1.4	S560L	Pathogenic	0.997
MEN1	O00255-1.4	S560M	Pathogenic	0.994
MEN1	O00255-1.4	S560N	Pathogenic	0.859
MEN1	O00255-1.4	S560P	Pathogenic	0.857
MEN1	O00255-1.4	S560Q	Pathogenic	0.93
MEN1	O00255-1.4	S560R	Pathogenic	0.998
MEN1	O00255-1.4	S560T	Pathogenic	0.758
MEN1	O00255-1.4	S560V	Pathogenic	0.978
MEN1	O00255-1.4	S560W	Pathogenic	1.0
MEN1	O00255-1.4	S560Y	Pathogenic	0.998
MEN1	O00255-1.4	E561A	Neutral	0.452
MEN1	O00255-1.4	E561C	Neutral	0.416
MEN1	O00255-1.4	E561D	Neutral	0.03
MEN1	O00255-1.4	E561F	Pathogenic	0.756
MEN1	O00255-1.4	E561G	Pathogenic	0.687
MEN1	O00255-1.4	E561H	Neutral	0.047
MEN1	O00255-1.4	E561I	Pathogenic	0.583
MEN1	O00255-1.4	E561K	Neutral	0.078
MEN1	O00255-1.4	E561L	Pathogenic	0.542
MEN1	O00255-1.4	E561M	Neutral	0.342
MEN1	O00255-1.4	E561N	Neutral	0.02
MEN1	O00255-1.4	E561P	Neutral	0.223
MEN1	O00255-1.4	E561Q	Neutral	0.018
MEN1	O00255-1.4	E561R	Neutral	0.195
MEN1	O00255-1.4	E561S	Neutral	0.221
MEN1	O00255-1.4	E561T	Neutral	0.098
MEN1	O00255-1.4	E561V	Neutral	0.183
MEN1	O00255-1.4	E561W	Pathogenic	0.982
MEN1	O00255-1.4	E561Y	Pathogenic	0.544
MEN1	O00255-1.4	K562A	Pathogenic	0.999
MEN1	O00255-1.4	K562C	Pathogenic	0.999
MEN1	O00255-1.4	K562D	Pathogenic	0.977
MEN1	O00255-1.4	K562E	Pathogenic	0.924
MEN1	O00255-1.4	K562F	Pathogenic	0.991
MEN1	O00255-1.4	K562G	Pathogenic	1.0
MEN1	O00255-1.4	K562H	Pathogenic	0.961
MEN1	O00255-1.4	K562I	Pathogenic	0.996
MEN1	O00255-1.4	K562L	Pathogenic	0.995
MEN1	O00255-1.4	K562M	Pathogenic	0.989
MEN1	O00255-1.4	K562N	Pathogenic	0.973
MEN1	O00255-1.4	K562P	Pathogenic	0.998
MEN1	O00255-1.4	K562Q	Pathogenic	0.943
MEN1	O00255-1.4	K562R	Pathogenic	0.716
MEN1	O00255-1.4	K562S	Pathogenic	0.998
MEN1	O00255-1.4	K562T	Pathogenic	0.995
MEN1	O00255-1.4	K562V	Pathogenic	0.998
MEN1	O00255-1.4	K562W	Pathogenic	0.999
MEN1	O00255-1.4	K562Y	Pathogenic	0.978
MEN1	O00255-1.4	M563A	Pathogenic	1.0
MEN1	O00255-1.4	M563C	Pathogenic	0.996
MEN1	O00255-1.4	M563D	Pathogenic	1.0
MEN1	O00255-1.4	M563E	Pathogenic	0.998
MEN1	O00255-1.4	M563F	Pathogenic	0.98
MEN1	O00255-1.4	M563G	Pathogenic	1.0
MEN1	O00255-1.4	M563H	Pathogenic	0.989
MEN1	O00255-1.4	M563I	Pathogenic	0.955
MEN1	O00255-1.4	M563K	Pathogenic	0.999
MEN1	O00255-1.4	M563L	Pathogenic	0.944
MEN1	O00255-1.4	M563N	Pathogenic	0.999
MEN1	O00255-1.4	M563P	Pathogenic	0.997
MEN1	O00255-1.4	M563Q	Pathogenic	0.995
MEN1	O00255-1.4	M563R	Pathogenic	1.0
MEN1	O00255-1.4	M563S	Pathogenic	1.0
MEN1	O00255-1.4	M563T	Pathogenic	0.998
MEN1	O00255-1.4	M563V	Pathogenic	0.972
MEN1	O00255-1.4	M563W	Pathogenic	0.999
MEN1	O00255-1.4	M563Y	Pathogenic	0.981
MEN1	O00255-1.4	K564A	Pathogenic	0.993
MEN1	O00255-1.4	K564C	Pathogenic	0.992
MEN1	O00255-1.4	K564D	Pathogenic	0.81
MEN1	O00255-1.4	K564E	Pathogenic	0.55
MEN1	O00255-1.4	K564F	Pathogenic	0.92
MEN1	O00255-1.4	K564G	Pathogenic	0.997
MEN1	O00255-1.4	K564H	Pathogenic	0.71
MEN1	O00255-1.4	K564I	Pathogenic	0.964
MEN1	O00255-1.4	K564L	Pathogenic	0.955
MEN1	O00255-1.4	K564M	Pathogenic	0.903
MEN1	O00255-1.4	K564N	Pathogenic	0.784
MEN1	O00255-1.4	K564P	Pathogenic	0.981
MEN1	O00255-1.4	K564Q	Pathogenic	0.624
MEN1	O00255-1.4	K564R	Neutral	0.201
MEN1	O00255-1.4	K564S	Pathogenic	0.981
MEN1	O00255-1.4	K564T	Pathogenic	0.951
MEN1	O00255-1.4	K564V	Pathogenic	0.976
MEN1	O00255-1.4	K564W	Pathogenic	0.995
MEN1	O00255-1.4	K564Y	Pathogenic	0.815
MEN1	O00255-1.4	G565A	Neutral	0.402
MEN1	O00255-1.4	G565C	Pathogenic	0.909
MEN1	O00255-1.4	G565D	Pathogenic	0.901
MEN1	O00255-1.4	G565E	Pathogenic	0.968
MEN1	O00255-1.4	G565F	Pathogenic	0.999
MEN1	O00255-1.4	G565H	Pathogenic	0.963
MEN1	O00255-1.4	G565I	Pathogenic	0.999
MEN1	O00255-1.4	G565K	Pathogenic	0.997
MEN1	O00255-1.4	G565L	Pathogenic	0.998
MEN1	O00255-1.4	G565M	Pathogenic	0.996
MEN1	O00255-1.4	G565N	Pathogenic	0.904
MEN1	O00255-1.4	G565P	Pathogenic	0.892
MEN1	O00255-1.4	G565Q	Pathogenic	0.956
MEN1	O00255-1.4	G565R	Pathogenic	0.999
MEN1	O00255-1.4	G565S	Neutral	0.404
MEN1	O00255-1.4	G565T	Pathogenic	0.829
MEN1	O00255-1.4	G565V	Pathogenic	0.984
MEN1	O00255-1.4	G565W	Pathogenic	1.0
MEN1	O00255-1.4	G565Y	Pathogenic	0.998
MEN1	O00255-1.4	M566A	Pathogenic	0.997
MEN1	O00255-1.4	M566C	Pathogenic	0.966
MEN1	O00255-1.4	M566D	Pathogenic	0.997
MEN1	O00255-1.4	M566E	Pathogenic	0.987
MEN1	O00255-1.4	M566F	Pathogenic	0.853
MEN1	O00255-1.4	M566G	Pathogenic	1.0
MEN1	O00255-1.4	M566H	Pathogenic	0.916
MEN1	O00255-1.4	M566I	Pathogenic	0.711
MEN1	O00255-1.4	M566K	Pathogenic	0.989
MEN1	O00255-1.4	M566L	Pathogenic	0.662
MEN1	O00255-1.4	M566N	Pathogenic	0.995
MEN1	O00255-1.4	M566P	Pathogenic	0.971
MEN1	O00255-1.4	M566Q	Pathogenic	0.958
MEN1	O00255-1.4	M566R	Pathogenic	0.996
MEN1	O00255-1.4	M566S	Pathogenic	0.997
MEN1	O00255-1.4	M566T	Pathogenic	0.982
MEN1	O00255-1.4	M566V	Pathogenic	0.804
MEN1	O00255-1.4	M566W	Pathogenic	0.991
MEN1	O00255-1.4	M566Y	Pathogenic	0.858
MEN1	O00255-1.4	K567A	Pathogenic	0.998
MEN1	O00255-1.4	K567C	Pathogenic	0.997
MEN1	O00255-1.4	K567D	Pathogenic	0.93
MEN1	O00255-1.4	K567E	Pathogenic	0.791
MEN1	O00255-1.4	K567F	Pathogenic	0.973
MEN1	O00255-1.4	K567G	Pathogenic	0.999
MEN1	O00255-1.4	K567H	Pathogenic	0.884
MEN1	O00255-1.4	K567I	Pathogenic	0.988
MEN1	O00255-1.4	K567L	Pathogenic	0.985
MEN1	O00255-1.4	K567M	Pathogenic	0.967
MEN1	O00255-1.4	K567N	Pathogenic	0.919
MEN1	O00255-1.4	K567P	Pathogenic	0.994
MEN1	O00255-1.4	K567Q	Pathogenic	0.837
MEN1	O00255-1.4	K567R	Neutral	0.439
MEN1	O00255-1.4	K567S	Pathogenic	0.994
MEN1	O00255-1.4	K567T	Pathogenic	0.984
MEN1	O00255-1.4	K567V	Pathogenic	0.992
MEN1	O00255-1.4	K567W	Pathogenic	0.998
MEN1	O00255-1.4	K567Y	Pathogenic	0.932
MEN1	O00255-1.4	E568A	Pathogenic	0.572
MEN1	O00255-1.4	E568C	Pathogenic	0.536
MEN1	O00255-1.4	E568D	Neutral	0.047
MEN1	O00255-1.4	E568F	Pathogenic	0.834
MEN1	O00255-1.4	E568G	Pathogenic	0.781
MEN1	O00255-1.4	E568H	Neutral	0.074
MEN1	O00255-1.4	E568I	Pathogenic	0.694
MEN1	O00255-1.4	E568K	Neutral	0.12
MEN1	O00255-1.4	E568L	Pathogenic	0.658
MEN1	O00255-1.4	E568M	Neutral	0.458
MEN1	O00255-1.4	E568N	Neutral	0.032
MEN1	O00255-1.4	E568P	Neutral	0.318
MEN1	O00255-1.4	E568Q	Neutral	0.029
MEN1	O00255-1.4	E568R	Neutral	0.282
MEN1	O00255-1.4	E568S	Neutral	0.315
MEN1	O00255-1.4	E568T	Neutral	0.15
MEN1	O00255-1.4	E568V	Neutral	0.266
MEN1	O00255-1.4	E568W	Pathogenic	0.989
MEN1	O00255-1.4	E568Y	Pathogenic	0.66
MEN1	O00255-1.4	L569A	Pathogenic	0.996
MEN1	O00255-1.4	L569C	Pathogenic	0.95
MEN1	O00255-1.4	L569D	Pathogenic	0.996
MEN1	O00255-1.4	L569E	Pathogenic	0.982
MEN1	O00255-1.4	L569F	Neutral	0.464
MEN1	O00255-1.4	L569G	Pathogenic	0.999
MEN1	O00255-1.4	L569H	Pathogenic	0.887
MEN1	O00255-1.4	L569I	Neutral	0.257
MEN1	O00255-1.4	L569K	Pathogenic	0.985
MEN1	O00255-1.4	L569M	Neutral	0.385
MEN1	O00255-1.4	L569N	Pathogenic	0.993
MEN1	O00255-1.4	L569P	Pathogenic	0.961
MEN1	O00255-1.4	L569Q	Pathogenic	0.946
MEN1	O00255-1.4	L569R	Pathogenic	0.994
MEN1	O00255-1.4	L569S	Pathogenic	0.996
MEN1	O00255-1.4	L569T	Pathogenic	0.974
MEN1	O00255-1.4	L569V	Pathogenic	0.738
MEN1	O00255-1.4	L569W	Pathogenic	0.943
MEN1	O00255-1.4	L569Y	Pathogenic	0.805
MEN1	O00255-1.4	L570A	Pathogenic	0.991
MEN1	O00255-1.4	L570C	Pathogenic	0.9
MEN1	O00255-1.4	L570D	Pathogenic	0.992
MEN1	O00255-1.4	L570E	Pathogenic	0.962
MEN1	O00255-1.4	L570F	Neutral	0.289
MEN1	O00255-1.4	L570G	Pathogenic	0.999
MEN1	O00255-1.4	L570H	Pathogenic	0.787
MEN1	O00255-1.4	L570I	Neutral	0.14
MEN1	O00255-1.4	L570K	Pathogenic	0.969
MEN1	O00255-1.4	L570M	Neutral	0.227
MEN1	O00255-1.4	L570N	Pathogenic	0.984
MEN1	O00255-1.4	L570P	Pathogenic	0.92
MEN1	O00255-1.4	L570Q	Pathogenic	0.893
MEN1	O00255-1.4	L570R	Pathogenic	0.988
MEN1	O00255-1.4	L570S	Pathogenic	0.992
MEN1	O00255-1.4	L570T	Pathogenic	0.945
MEN1	O00255-1.4	L570V	Pathogenic	0.569
MEN1	O00255-1.4	L570W	Pathogenic	0.887
MEN1	O00255-1.4	L570Y	Pathogenic	0.661
MEN1	O00255-1.4	V571A	Neutral	0.109
MEN1	O00255-1.4	V571C	Neutral	0.01
MEN1	O00255-1.4	V571D	Neutral	0.123
MEN1	O00255-1.4	V571E	Neutral	0.048
MEN1	O00255-1.4	V571F	Neutral	0.04
MEN1	O00255-1.4	V571G	Pathogenic	0.5
MEN1	O00255-1.4	V571H	Neutral	0.029
MEN1	O00255-1.4	V571I	Neutral	0.014
MEN1	O00255-1.4	V571K	Neutral	0.385
MEN1	O00255-1.4	V571L	Neutral	0.014
MEN1	O00255-1.4	V571M	Neutral	0.007
MEN1	O00255-1.4	V571N	Neutral	0.069
MEN1	O00255-1.4	V571P	Neutral	0.013
MEN1	O00255-1.4	V571Q	Neutral	0.036
MEN1	O00255-1.4	V571R	Pathogenic	0.642
MEN1	O00255-1.4	V571S	Neutral	0.134
MEN1	O00255-1.4	V571T	Neutral	0.019
MEN1	O00255-1.4	V571W	Neutral	0.445
MEN1	O00255-1.4	V571Y	Neutral	0.038
MEN1	O00255-1.4	A572C	Neutral	0.259
MEN1	O00255-1.4	A572D	Pathogenic	0.524
MEN1	O00255-1.4	A572E	Pathogenic	0.762
MEN1	O00255-1.4	A572F	Pathogenic	0.983
MEN1	O00255-1.4	A572G	Neutral	0.161
MEN1	O00255-1.4	A572H	Pathogenic	0.657
MEN1	O00255-1.4	A572I	Pathogenic	0.96
MEN1	O00255-1.4	A572K	Pathogenic	0.975
MEN1	O00255-1.4	A572L	Pathogenic	0.953
MEN1	O00255-1.4	A572M	Pathogenic	0.905
MEN1	O00255-1.4	A572N	Pathogenic	0.549
MEN1	O00255-1.4	A572P	Neutral	0.246
MEN1	O00255-1.4	A572Q	Pathogenic	0.703
MEN1	O00255-1.4	A572R	Pathogenic	0.991
MEN1	O00255-1.4	A572S	Neutral	0.068
MEN1	O00255-1.4	A572T	Neutral	0.176
MEN1	O00255-1.4	A572V	Pathogenic	0.679
MEN1	O00255-1.4	A572W	Pathogenic	0.999
MEN1	O00255-1.4	A572Y	Pathogenic	0.959
MEN1	O00255-1.4	T573A	Neutral	0.025
MEN1	O00255-1.4	T573C	Neutral	0.019
MEN1	O00255-1.4	T573D	Neutral	0.021
MEN1	O00255-1.4	T573E	Neutral	0.047
MEN1	O00255-1.4	T573F	Pathogenic	0.509
MEN1	O00255-1.4	T573G	Neutral	0.141
MEN1	O00255-1.4	T573H	Neutral	0.029
MEN1	O00255-1.4	T573I	Neutral	0.305
MEN1	O00255-1.4	T573K	Neutral	0.38
MEN1	O00255-1.4	T573L	Neutral	0.271
MEN1	O00255-1.4	T573M	Neutral	0.148
MEN1	O00255-1.4	T573N	Neutral	0.016
MEN1	O00255-1.4	T573P	Neutral	0.009
MEN1	O00255-1.4	T573Q	Neutral	0.035
MEN1	O00255-1.4	T573R	Pathogenic	0.624
MEN1	O00255-1.4	T573S	Neutral	0.022
MEN1	O00255-1.4	T573V	Neutral	0.037
MEN1	O00255-1.4	T573W	Pathogenic	0.947
MEN1	O00255-1.4	T573Y	Neutral	0.297
MEN1	O00255-1.4	K574A	Pathogenic	0.999
MEN1	O00255-1.4	K574C	Pathogenic	0.998
MEN1	O00255-1.4	K574D	Pathogenic	0.957
MEN1	O00255-1.4	K574E	Pathogenic	0.866
MEN1	O00255-1.4	K574F	Pathogenic	0.984
MEN1	O00255-1.4	K574G	Pathogenic	1.0
MEN1	O00255-1.4	K574H	Pathogenic	0.928
MEN1	O00255-1.4	K574I	Pathogenic	0.993
MEN1	O00255-1.4	K574L	Pathogenic	0.991
MEN1	O00255-1.4	K574M	Pathogenic	0.98
MEN1	O00255-1.4	K574N	Pathogenic	0.95
MEN1	O00255-1.4	K574P	Pathogenic	0.996
MEN1	O00255-1.4	K574Q	Pathogenic	0.897
MEN1	O00255-1.4	K574R	Pathogenic	0.571
MEN1	O00255-1.4	K574S	Pathogenic	0.996
MEN1	O00255-1.4	K574T	Pathogenic	0.99
MEN1	O00255-1.4	K574V	Pathogenic	0.995
MEN1	O00255-1.4	K574W	Pathogenic	0.999
MEN1	O00255-1.4	K574Y	Pathogenic	0.959
MEN1	O00255-1.4	I575A	Pathogenic	0.936
MEN1	O00255-1.4	I575C	Pathogenic	0.543
MEN1	O00255-1.4	I575D	Pathogenic	0.941
MEN1	O00255-1.4	I575E	Pathogenic	0.769
MEN1	O00255-1.4	I575F	Neutral	0.039
MEN1	O00255-1.4	I575G	Pathogenic	0.992
MEN1	O00255-1.4	I575H	Neutral	0.328
MEN1	O00255-1.4	I575K	Pathogenic	0.814
MEN1	O00255-1.4	I575L	Neutral	0.018
MEN1	O00255-1.4	I575M	Neutral	0.04
MEN1	O00255-1.4	I575N	Pathogenic	0.892
MEN1	O00255-1.4	I575P	Pathogenic	0.604
MEN1	O00255-1.4	I575Q	Pathogenic	0.538
MEN1	O00255-1.4	I575R	Pathogenic	0.922
MEN1	O00255-1.4	I575S	Pathogenic	0.946
MEN1	O00255-1.4	I575T	Pathogenic	0.696
MEN1	O00255-1.4	I575V	Neutral	0.134
MEN1	O00255-1.4	I575W	Neutral	0.441
MEN1	O00255-1.4	I575Y	Neutral	0.204
MEN1	O00255-1.4	N576A	Pathogenic	0.99
MEN1	O00255-1.4	N576C	Pathogenic	0.987
MEN1	O00255-1.4	N576D	Pathogenic	0.808
MEN1	O00255-1.4	N576E	Pathogenic	0.867
MEN1	O00255-1.4	N576F	Pathogenic	1.0
MEN1	O00255-1.4	N576G	Pathogenic	0.996
MEN1	O00255-1.4	N576H	Pathogenic	0.974
MEN1	O00255-1.4	N576I	Pathogenic	0.999
MEN1	O00255-1.4	N576K	Pathogenic	0.988
MEN1	O00255-1.4	N576L	Pathogenic	0.999
MEN1	O00255-1.4	N576M	Pathogenic	0.998
MEN1	O00255-1.4	N576P	Pathogenic	0.972
MEN1	O00255-1.4	N576Q	Pathogenic	0.943
MEN1	O00255-1.4	N576R	Pathogenic	0.995
MEN1	O00255-1.4	N576S	Pathogenic	0.968
MEN1	O00255-1.4	N576T	Pathogenic	0.922
MEN1	O00255-1.4	N576V	Pathogenic	0.991
MEN1	O00255-1.4	N576W	Pathogenic	1.0
MEN1	O00255-1.4	N576Y	Pathogenic	0.999
MEN1	O00255-1.4	S577A	Neutral	0.05
MEN1	O00255-1.4	S577C	Neutral	0.231
MEN1	O00255-1.4	S577D	Neutral	0.205
MEN1	O00255-1.4	S577E	Neutral	0.444
MEN1	O00255-1.4	S577F	Pathogenic	0.979
MEN1	O00255-1.4	S577G	Neutral	0.123
MEN1	O00255-1.4	S577H	Neutral	0.452
MEN1	O00255-1.4	S577I	Pathogenic	0.954
MEN1	O00255-1.4	S577K	Pathogenic	0.908
MEN1	O00255-1.4	S577L	Pathogenic	0.946
MEN1	O00255-1.4	S577M	Pathogenic	0.885
MEN1	O00255-1.4	S577N	Neutral	0.212
MEN1	O00255-1.4	S577P	Neutral	0.208
MEN1	O00255-1.4	S577Q	Neutral	0.371
MEN1	O00255-1.4	S577R	Pathogenic	0.966
MEN1	O00255-1.4	S577T	Neutral	0.121
MEN1	O00255-1.4	S577V	Pathogenic	0.658
MEN1	O00255-1.4	S577W	Pathogenic	0.999
MEN1	O00255-1.4	S577Y	Pathogenic	0.949
MEN1	O00255-1.4	S578A	Neutral	0.064
MEN1	O00255-1.4	S578C	Neutral	0.279
MEN1	O00255-1.4	S578D	Neutral	0.249
MEN1	O00255-1.4	S578E	Pathogenic	0.507
MEN1	O00255-1.4	S578F	Pathogenic	0.983
MEN1	O00255-1.4	S578G	Neutral	0.153
MEN1	O00255-1.4	S578H	Pathogenic	0.515
MEN1	O00255-1.4	S578I	Pathogenic	0.964
MEN1	O00255-1.4	S578K	Pathogenic	0.927
MEN1	O00255-1.4	S578L	Pathogenic	0.957
MEN1	O00255-1.4	S578M	Pathogenic	0.908
MEN1	O00255-1.4	S578N	Neutral	0.257
MEN1	O00255-1.4	S578P	Neutral	0.253
MEN1	O00255-1.4	S578Q	Neutral	0.431
MEN1	O00255-1.4	S578R	Pathogenic	0.973
MEN1	O00255-1.4	S578T	Neutral	0.151
MEN1	O00255-1.4	S578V	Pathogenic	0.713
MEN1	O00255-1.4	S578W	Pathogenic	0.999
MEN1	O00255-1.4	S578Y	Pathogenic	0.96
MEN1	O00255-1.4	A579C	Pathogenic	0.775
MEN1	O00255-1.4	A579D	Pathogenic	0.915
MEN1	O00255-1.4	A579E	Pathogenic	0.969
MEN1	O00255-1.4	A579F	Pathogenic	0.998
MEN1	O00255-1.4	A579G	Pathogenic	0.655
MEN1	O00255-1.4	A579H	Pathogenic	0.95
MEN1	O00255-1.4	A579I	Pathogenic	0.996
MEN1	O00255-1.4	A579K	Pathogenic	0.997
MEN1	O00255-1.4	A579L	Pathogenic	0.995
MEN1	O00255-1.4	A579M	Pathogenic	0.989
MEN1	O00255-1.4	A579N	Pathogenic	0.923
MEN1	O00255-1.4	A579P	Pathogenic	0.762
MEN1	O00255-1.4	A579Q	Pathogenic	0.959
MEN1	O00255-1.4	A579R	Pathogenic	0.999
MEN1	O00255-1.4	A579S	Neutral	0.418
MEN1	O00255-1.4	A579T	Pathogenic	0.678
MEN1	O00255-1.4	A579V	Pathogenic	0.954
MEN1	O00255-1.4	A579W	Pathogenic	1.0
MEN1	O00255-1.4	A579Y	Pathogenic	0.996
MEN1	O00255-1.4	I580A	Pathogenic	0.999
MEN1	O00255-1.4	I580C	Pathogenic	0.991
MEN1	O00255-1.4	I580D	Pathogenic	0.999
MEN1	O00255-1.4	I580E	Pathogenic	0.997
MEN1	O00255-1.4	I580F	Pathogenic	0.795
MEN1	O00255-1.4	I580G	Pathogenic	1.0
MEN1	O00255-1.4	I580H	Pathogenic	0.979
MEN1	O00255-1.4	I580K	Pathogenic	0.998
MEN1	O00255-1.4	I580L	Pathogenic	0.635
MEN1	O00255-1.4	I580M	Pathogenic	0.798
MEN1	O00255-1.4	I580N	Pathogenic	0.999
MEN1	O00255-1.4	I580P	Pathogenic	0.993
MEN1	O00255-1.4	I580Q	Pathogenic	0.991
MEN1	O00255-1.4	I580R	Pathogenic	0.999
MEN1	O00255-1.4	I580S	Pathogenic	0.999
MEN1	O00255-1.4	I580T	Pathogenic	0.995
MEN1	O00255-1.4	I580V	Pathogenic	0.937
MEN1	O00255-1.4	I580W	Pathogenic	0.987
MEN1	O00255-1.4	I580Y	Pathogenic	0.961
MEN1	O00255-1.4	K581A	Pathogenic	0.983
MEN1	O00255-1.4	K581C	Pathogenic	0.98
MEN1	O00255-1.4	K581D	Pathogenic	0.632
MEN1	O00255-1.4	K581E	Neutral	0.33
MEN1	O00255-1.4	K581F	Pathogenic	0.822
MEN1	O00255-1.4	K581G	Pathogenic	0.994
MEN1	O00255-1.4	K581H	Neutral	0.497
MEN1	O00255-1.4	K581I	Pathogenic	0.915
MEN1	O00255-1.4	K581L	Pathogenic	0.895
MEN1	O00255-1.4	K581M	Pathogenic	0.79
MEN1	O00255-1.4	K581N	Pathogenic	0.594
MEN1	O00255-1.4	K581P	Pathogenic	0.954
MEN1	O00255-1.4	K581Q	Neutral	0.4
MEN1	O00255-1.4	K581R	Neutral	0.092
MEN1	O00255-1.4	K581S	Pathogenic	0.953
MEN1	O00255-1.4	K581T	Pathogenic	0.887
MEN1	O00255-1.4	K581V	Pathogenic	0.942
MEN1	O00255-1.4	K581W	Pathogenic	0.987
MEN1	O00255-1.4	K581Y	Pathogenic	0.639
MEN1	O00255-1.4	L582A	Pathogenic	0.997
MEN1	O00255-1.4	L582C	Pathogenic	0.959
MEN1	O00255-1.4	L582D	Pathogenic	0.997
MEN1	O00255-1.4	L582E	Pathogenic	0.985
MEN1	O00255-1.4	L582F	Pathogenic	0.516
MEN1	O00255-1.4	L582G	Pathogenic	1.0
MEN1	O00255-1.4	L582H	Pathogenic	0.907
MEN1	O00255-1.4	L582I	Neutral	0.299
MEN1	O00255-1.4	L582K	Pathogenic	0.988
MEN1	O00255-1.4	L582M	Neutral	0.436
MEN1	O00255-1.4	L582N	Pathogenic	0.994
MEN1	O00255-1.4	L582P	Pathogenic	0.968
MEN1	O00255-1.4	L582Q	Pathogenic	0.956
MEN1	O00255-1.4	L582R	Pathogenic	0.996
MEN1	O00255-1.4	L582S	Pathogenic	0.997
MEN1	O00255-1.4	L582T	Pathogenic	0.979
MEN1	O00255-1.4	L582V	Pathogenic	0.776
MEN1	O00255-1.4	L582W	Pathogenic	0.954
MEN1	O00255-1.4	L582Y	Pathogenic	0.836
MEN1	O00255-1.4	Q583A	Pathogenic	0.985
MEN1	O00255-1.4	Q583C	Pathogenic	0.982
MEN1	O00255-1.4	Q583D	Pathogenic	0.916
MEN1	O00255-1.4	Q583E	Pathogenic	0.67
MEN1	O00255-1.4	Q583F	Pathogenic	0.992
MEN1	O00255-1.4	Q583G	Pathogenic	0.994
MEN1	O00255-1.4	Q583H	Pathogenic	0.657
MEN1	O00255-1.4	Q583I	Pathogenic	0.982
MEN1	O00255-1.4	Q583K	Pathogenic	0.927
MEN1	O00255-1.4	Q583L	Pathogenic	0.977
MEN1	O00255-1.4	Q583M	Pathogenic	0.947
MEN1	O00255-1.4	Q583N	Pathogenic	0.851
MEN1	O00255-1.4	Q583P	Pathogenic	0.959
MEN1	O00255-1.4	Q583R	Pathogenic	0.972
MEN1	O00255-1.4	Q583S	Pathogenic	0.958
MEN1	O00255-1.4	Q583T	Pathogenic	0.898
MEN1	O00255-1.4	Q583V	Pathogenic	0.948
MEN1	O00255-1.4	Q583W	Pathogenic	0.999
MEN1	O00255-1.4	Q583Y	Pathogenic	0.977
MEN1	O00255-1.4	L584A	Pathogenic	0.986
MEN1	O00255-1.4	L584C	Pathogenic	0.852
MEN1	O00255-1.4	L584D	Pathogenic	0.988
MEN1	O00255-1.4	L584E	Pathogenic	0.942
MEN1	O00255-1.4	L584F	Neutral	0.206
MEN1	O00255-1.4	L584G	Pathogenic	0.998
MEN1	O00255-1.4	L584H	Pathogenic	0.703
MEN1	O00255-1.4	L584I	Neutral	0.094
MEN1	O00255-1.4	L584K	Pathogenic	0.952
MEN1	O00255-1.4	L584M	Neutral	0.158
MEN1	O00255-1.4	L584N	Pathogenic	0.976
MEN1	O00255-1.4	L584P	Pathogenic	0.881
MEN1	O00255-1.4	L584Q	Pathogenic	0.842
MEN1	O00255-1.4	L584R	Pathogenic	0.982
MEN1	O00255-1.4	L584S	Pathogenic	0.988
MEN1	O00255-1.4	L584T	Pathogenic	0.917
MEN1	O00255-1.4	L584V	Neutral	0.458
MEN1	O00255-1.4	L584W	Pathogenic	0.834
MEN1	O00255-1.4	L584Y	Pathogenic	0.555
MEN1	O00255-1.4	T585A	Pathogenic	0.938
MEN1	O00255-1.4	T585C	Pathogenic	0.92
MEN1	O00255-1.4	T585D	Pathogenic	0.928
MEN1	O00255-1.4	T585E	Pathogenic	0.967
MEN1	O00255-1.4	T585F	Pathogenic	0.998
MEN1	O00255-1.4	T585G	Pathogenic	0.99
MEN1	O00255-1.4	T585H	Pathogenic	0.947
MEN1	O00255-1.4	T585I	Pathogenic	0.996
MEN1	O00255-1.4	T585K	Pathogenic	0.997
MEN1	O00255-1.4	T585L	Pathogenic	0.996
MEN1	O00255-1.4	T585M	Pathogenic	0.99
MEN1	O00255-1.4	T585N	Pathogenic	0.909
MEN1	O00255-1.4	T585P	Pathogenic	0.848
MEN1	O00255-1.4	T585Q	Pathogenic	0.956
MEN1	O00255-1.4	T585R	Pathogenic	0.999
MEN1	O00255-1.4	T585S	Pathogenic	0.931
MEN1	O00255-1.4	T585V	Pathogenic	0.959
MEN1	O00255-1.4	T585W	Pathogenic	1.0
MEN1	O00255-1.4	T585Y	Pathogenic	0.996
MEN1	O00255-1.4	A586C	Pathogenic	0.821
MEN1	O00255-1.4	A586D	Pathogenic	0.935
MEN1	O00255-1.4	A586E	Pathogenic	0.977
MEN1	O00255-1.4	A586F	Pathogenic	0.999
MEN1	O00255-1.4	A586G	Pathogenic	0.716
MEN1	O00255-1.4	A586H	Pathogenic	0.962
MEN1	O00255-1.4	A586I	Pathogenic	0.997
MEN1	O00255-1.4	A586K	Pathogenic	0.998
MEN1	O00255-1.4	A586L	Pathogenic	0.996
MEN1	O00255-1.4	A586M	Pathogenic	0.992
MEN1	O00255-1.4	A586N	Pathogenic	0.941
MEN1	O00255-1.4	A586P	Pathogenic	0.81
MEN1	O00255-1.4	A586Q	Pathogenic	0.969
MEN1	O00255-1.4	A586R	Pathogenic	0.999
MEN1	O00255-1.4	A586S	Neutral	0.488
MEN1	O00255-1.4	A586T	Pathogenic	0.737
MEN1	O00255-1.4	A586V	Pathogenic	0.965
MEN1	O00255-1.4	A586W	Pathogenic	1.0
MEN1	O00255-1.4	A586Y	Pathogenic	0.997
MEN1	O00255-1.4	Q587A	Pathogenic	0.988
MEN1	O00255-1.4	Q587C	Pathogenic	0.985
MEN1	O00255-1.4	Q587D	Pathogenic	0.93
MEN1	O00255-1.4	Q587E	Pathogenic	0.714
MEN1	O00255-1.4	Q587F	Pathogenic	0.993
MEN1	O00255-1.4	Q587G	Pathogenic	0.995
MEN1	O00255-1.4	Q587H	Pathogenic	0.701
MEN1	O00255-1.4	Q587I	Pathogenic	0.985
MEN1	O00255-1.4	Q587K	Pathogenic	0.939
MEN1	O00255-1.4	Q587L	Pathogenic	0.981
MEN1	O00255-1.4	Q587M	Pathogenic	0.956
MEN1	O00255-1.4	Q587N	Pathogenic	0.875
MEN1	O00255-1.4	Q587P	Pathogenic	0.966
MEN1	O00255-1.4	Q587R	Pathogenic	0.977
MEN1	O00255-1.4	Q587S	Pathogenic	0.966
MEN1	O00255-1.4	Q587T	Pathogenic	0.916
MEN1	O00255-1.4	Q587V	Pathogenic	0.957
MEN1	O00255-1.4	Q587W	Pathogenic	1.0
MEN1	O00255-1.4	Q587Y	Pathogenic	0.982
MEN1	O00255-1.4	S588A	Pathogenic	0.516
MEN1	O00255-1.4	S588C	Pathogenic	0.858
MEN1	O00255-1.4	S588D	Pathogenic	0.839
MEN1	O00255-1.4	S588E	Pathogenic	0.942
MEN1	O00255-1.4	S588F	Pathogenic	0.999
MEN1	O00255-1.4	S588G	Pathogenic	0.74
MEN1	O00255-1.4	S588H	Pathogenic	0.943
MEN1	O00255-1.4	S588I	Pathogenic	0.998
MEN1	O00255-1.4	S588K	Pathogenic	0.995
MEN1	O00255-1.4	S588L	Pathogenic	0.997
MEN1	O00255-1.4	S588M	Pathogenic	0.994
MEN1	O00255-1.4	S588N	Pathogenic	0.844
MEN1	O00255-1.4	S588P	Pathogenic	0.842
MEN1	O00255-1.4	S588Q	Pathogenic	0.923
MEN1	O00255-1.4	S588R	Pathogenic	0.998
MEN1	O00255-1.4	S588T	Pathogenic	0.736
MEN1	O00255-1.4	S588V	Pathogenic	0.975
MEN1	O00255-1.4	S588W	Pathogenic	1.0
MEN1	O00255-1.4	S588Y	Pathogenic	0.997
MEN1	O00255-1.4	Q589A	Pathogenic	0.985
MEN1	O00255-1.4	Q589C	Pathogenic	0.981
MEN1	O00255-1.4	Q589D	Pathogenic	0.914
MEN1	O00255-1.4	Q589E	Pathogenic	0.664
MEN1	O00255-1.4	Q589F	Pathogenic	0.991
MEN1	O00255-1.4	Q589G	Pathogenic	0.994
MEN1	O00255-1.4	Q589H	Pathogenic	0.65
MEN1	O00255-1.4	Q589I	Pathogenic	0.981
MEN1	O00255-1.4	Q589K	Pathogenic	0.925
MEN1	O00255-1.4	Q589L	Pathogenic	0.977
MEN1	O00255-1.4	Q589M	Pathogenic	0.945
MEN1	O00255-1.4	Q589N	Pathogenic	0.847
MEN1	O00255-1.4	Q589P	Pathogenic	0.958
MEN1	O00255-1.4	Q589R	Pathogenic	0.971
MEN1	O00255-1.4	Q589S	Pathogenic	0.957
MEN1	O00255-1.4	Q589T	Pathogenic	0.896
MEN1	O00255-1.4	Q589V	Pathogenic	0.946
MEN1	O00255-1.4	Q589W	Pathogenic	0.999
MEN1	O00255-1.4	Q589Y	Pathogenic	0.977
MEN1	O00255-1.4	V590A	Pathogenic	0.931
MEN1	O00255-1.4	V590C	Pathogenic	0.536
MEN1	O00255-1.4	V590D	Pathogenic	0.939
MEN1	O00255-1.4	V590E	Pathogenic	0.847
MEN1	O00255-1.4	V590F	Pathogenic	0.82
MEN1	O00255-1.4	V590G	Pathogenic	0.991
MEN1	O00255-1.4	V590H	Pathogenic	0.768
MEN1	O00255-1.4	V590I	Pathogenic	0.616
MEN1	O00255-1.4	V590K	Pathogenic	0.986
MEN1	O00255-1.4	V590L	Pathogenic	0.606
MEN1	O00255-1.4	V590M	Neutral	0.418
MEN1	O00255-1.4	V590N	Pathogenic	0.89
MEN1	O00255-1.4	V590P	Pathogenic	0.583
MEN1	O00255-1.4	V590Q	Pathogenic	0.803
MEN1	O00255-1.4	V590R	Pathogenic	0.995
MEN1	O00255-1.4	V590S	Pathogenic	0.944
MEN1	O00255-1.4	V590T	Pathogenic	0.677
MEN1	O00255-1.4	V590W	Pathogenic	0.989
MEN1	O00255-1.4	V590Y	Pathogenic	0.81
MEN1	O00255-1.4	Q591A	Pathogenic	0.962
MEN1	O00255-1.4	Q591C	Pathogenic	0.954
MEN1	O00255-1.4	Q591D	Pathogenic	0.806
MEN1	O00255-1.4	Q591E	Neutral	0.436
MEN1	O00255-1.4	Q591F	Pathogenic	0.979
MEN1	O00255-1.4	Q591G	Pathogenic	0.986
MEN1	O00255-1.4	Q591H	Neutral	0.421
MEN1	O00255-1.4	Q591I	Pathogenic	0.954
MEN1	O00255-1.4	Q591K	Pathogenic	0.828
MEN1	O00255-1.4	Q591L	Pathogenic	0.942
MEN1	O00255-1.4	Q591M	Pathogenic	0.872
MEN1	O00255-1.4	Q591N	Pathogenic	0.685
MEN1	O00255-1.4	Q591P	Pathogenic	0.899
MEN1	O00255-1.4	Q591R	Pathogenic	0.929
MEN1	O00255-1.4	Q591S	Pathogenic	0.898
MEN1	O00255-1.4	Q591T	Pathogenic	0.771
MEN1	O00255-1.4	Q591V	Pathogenic	0.874
MEN1	O00255-1.4	Q591W	Pathogenic	0.999
MEN1	O00255-1.4	Q591Y	Pathogenic	0.943
MEN1	O00255-1.4	M592A	Pathogenic	0.955
MEN1	O00255-1.4	M592C	Pathogenic	0.631
MEN1	O00255-1.4	M592D	Pathogenic	0.958
MEN1	O00255-1.4	M592E	Pathogenic	0.819
MEN1	O00255-1.4	M592F	Neutral	0.261
MEN1	O00255-1.4	M592G	Pathogenic	0.994
MEN1	O00255-1.4	M592H	Neutral	0.398
MEN1	O00255-1.4	M592I	Neutral	0.13
MEN1	O00255-1.4	M592K	Pathogenic	0.848
MEN1	O00255-1.4	M592L	Neutral	0.107
MEN1	O00255-1.4	M592N	Pathogenic	0.918
MEN1	O00255-1.4	M592P	Pathogenic	0.674
MEN1	O00255-1.4	M592Q	Pathogenic	0.583
MEN1	O00255-1.4	M592R	Pathogenic	0.938
MEN1	O00255-1.4	M592S	Pathogenic	0.959
MEN1	O00255-1.4	M592T	Pathogenic	0.767
MEN1	O00255-1.4	M592V	Neutral	0.201
MEN1	O00255-1.4	M592W	Pathogenic	0.865
MEN1	O00255-1.4	M592Y	Neutral	0.27
MEN1	O00255-1.4	K593A	Pathogenic	0.94
MEN1	O00255-1.4	K593C	Pathogenic	0.927
MEN1	O00255-1.4	K593D	Neutral	0.313
MEN1	O00255-1.4	K593E	Neutral	0.115
MEN1	O00255-1.4	K593F	Pathogenic	0.549
MEN1	O00255-1.4	K593G	Pathogenic	0.977
MEN1	O00255-1.4	K593H	Neutral	0.207
MEN1	O00255-1.4	K593I	Pathogenic	0.739
MEN1	O00255-1.4	K593L	Pathogenic	0.693
MEN1	O00255-1.4	K593M	Neutral	0.499
MEN1	O00255-1.4	K593N	Neutral	0.279
MEN1	O00255-1.4	K593P	Pathogenic	0.846
MEN1	O00255-1.4	K593Q	Neutral	0.15
MEN1	O00255-1.4	K593R	Neutral	0.026
MEN1	O00255-1.4	K593S	Pathogenic	0.844
MEN1	O00255-1.4	K593T	Pathogenic	0.674
MEN1	O00255-1.4	K593V	Pathogenic	0.81
MEN1	O00255-1.4	K593W	Pathogenic	0.954
MEN1	O00255-1.4	K593Y	Neutral	0.319
MEN1	O00255-1.4	K594A	Pathogenic	0.943
MEN1	O00255-1.4	K594C	Pathogenic	0.931
MEN1	O00255-1.4	K594D	Neutral	0.324
MEN1	O00255-1.4	K594E	Neutral	0.12
MEN1	O00255-1.4	K594F	Pathogenic	0.561
MEN1	O00255-1.4	K594G	Pathogenic	0.978
MEN1	O00255-1.4	K594H	Neutral	0.216
MEN1	O00255-1.4	K594I	Pathogenic	0.749
MEN1	O00255-1.4	K594L	Pathogenic	0.704
MEN1	O00255-1.4	K594M	Pathogenic	0.511
MEN1	O00255-1.4	K594N	Neutral	0.29
MEN1	O00255-1.4	K594P	Pathogenic	0.852
MEN1	O00255-1.4	K594Q	Neutral	0.157
MEN1	O00255-1.4	K594R	Neutral	0.027
MEN1	O00255-1.4	K594S	Pathogenic	0.85
MEN1	O00255-1.4	K594T	Pathogenic	0.685
MEN1	O00255-1.4	K594V	Pathogenic	0.818
MEN1	O00255-1.4	K594W	Pathogenic	0.956
MEN1	O00255-1.4	K594Y	Neutral	0.33
MEN1	O00255-1.4	Q595A	Neutral	0.371
MEN1	O00255-1.4	Q595C	Neutral	0.325
MEN1	O00255-1.4	Q595D	Neutral	0.088
MEN1	O00255-1.4	Q595E	Neutral	0.018
MEN1	O00255-1.4	Q595F	Pathogenic	0.513
MEN1	O00255-1.4	Q595G	Pathogenic	0.611
MEN1	O00255-1.4	Q595H	Neutral	0.017
MEN1	O00255-1.4	Q595I	Neutral	0.322
MEN1	O00255-1.4	Q595K	Neutral	0.1
MEN1	O00255-1.4	Q595L	Neutral	0.275
MEN1	O00255-1.4	Q595M	Neutral	0.136
MEN1	O00255-1.4	Q595N	Neutral	0.048
MEN1	O00255-1.4	Q595P	Neutral	0.171
MEN1	O00255-1.4	Q595R	Neutral	0.231
MEN1	O00255-1.4	Q595S	Neutral	0.169
MEN1	O00255-1.4	Q595T	Neutral	0.072
MEN1	O00255-1.4	Q595V	Neutral	0.138
MEN1	O00255-1.4	Q595W	Pathogenic	0.944
MEN1	O00255-1.4	Q595Y	Neutral	0.276
MEN1	O00255-1.4	K596A	Pathogenic	0.983
MEN1	O00255-1.4	K596C	Pathogenic	0.979
MEN1	O00255-1.4	K596D	Pathogenic	0.624
MEN1	O00255-1.4	K596E	Neutral	0.322
MEN1	O00255-1.4	K596F	Pathogenic	0.816
MEN1	O00255-1.4	K596G	Pathogenic	0.993
MEN1	O00255-1.4	K596H	Neutral	0.489
MEN1	O00255-1.4	K596I	Pathogenic	0.912
MEN1	O00255-1.4	K596L	Pathogenic	0.892
MEN1	O00255-1.4	K596M	Pathogenic	0.784
MEN1	O00255-1.4	K596N	Pathogenic	0.586
MEN1	O00255-1.4	K596P	Pathogenic	0.952
MEN1	O00255-1.4	K596Q	Neutral	0.392
MEN1	O00255-1.4	K596R	Neutral	0.089
MEN1	O00255-1.4	K596S	Pathogenic	0.952
MEN1	O00255-1.4	K596T	Pathogenic	0.883
MEN1	O00255-1.4	K596V	Pathogenic	0.94
MEN1	O00255-1.4	K596W	Pathogenic	0.987
MEN1	O00255-1.4	K596Y	Pathogenic	0.631
MEN1	O00255-1.4	V597A	Neutral	0.032
MEN1	O00255-1.4	V597C	Neutral	0.003
MEN1	O00255-1.4	V597D	Neutral	0.036
MEN1	O00255-1.4	V597E	Neutral	0.013
MEN1	O00255-1.4	V597F	Neutral	0.011
MEN1	O00255-1.4	V597G	Neutral	0.211
MEN1	O00255-1.4	V597H	Neutral	0.008
MEN1	O00255-1.4	V597I	Neutral	0.004
MEN1	O00255-1.4	V597K	Neutral	0.143
MEN1	O00255-1.4	V597L	Neutral	0.004
MEN1	O00255-1.4	V597M	Neutral	0.002
MEN1	O00255-1.4	V597N	Neutral	0.019
MEN1	O00255-1.4	V597P	Neutral	0.003
MEN1	O00255-1.4	V597Q	Neutral	0.01
MEN1	O00255-1.4	V597R	Neutral	0.325
MEN1	O00255-1.4	V597S	Neutral	0.04
MEN1	O00255-1.4	V597T	Neutral	0.005
MEN1	O00255-1.4	V597W	Neutral	0.177
MEN1	O00255-1.4	V597Y	Neutral	0.01
MEN1	O00255-1.4	S598A	Neutral	0.004
MEN1	O00255-1.4	S598C	Neutral	0.021
MEN1	O00255-1.4	S598D	Neutral	0.018
MEN1	O00255-1.4	S598E	Neutral	0.054
MEN1	O00255-1.4	S598F	Pathogenic	0.765
MEN1	O00255-1.4	S598G	Neutral	0.01
MEN1	O00255-1.4	S598H	Neutral	0.055
MEN1	O00255-1.4	S598I	Pathogenic	0.595
MEN1	O00255-1.4	S598K	Neutral	0.413
MEN1	O00255-1.4	S598L	Pathogenic	0.554
MEN1	O00255-1.4	S598M	Neutral	0.354
MEN1	O00255-1.4	S598N	Neutral	0.019
MEN1	O00255-1.4	S598P	Neutral	0.018
MEN1	O00255-1.4	S598Q	Neutral	0.04
MEN1	O00255-1.4	S598R	Pathogenic	0.669
MEN1	O00255-1.4	S598T	Neutral	0.01
MEN1	O00255-1.4	S598V	Neutral	0.121
MEN1	O00255-1.4	S598W	Pathogenic	0.983
MEN1	O00255-1.4	S598Y	Pathogenic	0.571
MEN1	O00255-1.4	T599A	Neutral	0.069
MEN1	O00255-1.4	T599C	Neutral	0.054
MEN1	O00255-1.4	T599D	Neutral	0.06
MEN1	O00255-1.4	T599E	Neutral	0.128
MEN1	O00255-1.4	T599F	Pathogenic	0.754
MEN1	O00255-1.4	T599G	Neutral	0.326
MEN1	O00255-1.4	T599H	Neutral	0.081
MEN1	O00255-1.4	T599I	Pathogenic	0.565
MEN1	O00255-1.4	T599K	Pathogenic	0.644
MEN1	O00255-1.4	T599L	Pathogenic	0.524
MEN1	O00255-1.4	T599M	Neutral	0.339
MEN1	O00255-1.4	T599N	Neutral	0.047
MEN1	O00255-1.4	T599P	Neutral	0.027
MEN1	O00255-1.4	T599Q	Neutral	0.098
MEN1	O00255-1.4	T599R	Pathogenic	0.831
MEN1	O00255-1.4	T599S	Neutral	0.062
MEN1	O00255-1.4	T599V	Neutral	0.102
MEN1	O00255-1.4	T599W	Pathogenic	0.981
MEN1	O00255-1.4	T599Y	Pathogenic	0.556
MEN1	O00255-1.4	P600A	Neutral	0.035
MEN1	O00255-1.4	P600C	Neutral	0.008
MEN1	O00255-1.4	P600D	Neutral	0.039
MEN1	O00255-1.4	P600E	Neutral	0.111
MEN1	O00255-1.4	P600F	Neutral	0.395
MEN1	O00255-1.4	P600G	Neutral	0.208
MEN1	O00255-1.4	P600H	Neutral	0.069
MEN1	O00255-1.4	P600I	Neutral	0.217
MEN1	O00255-1.4	P600K	Pathogenic	0.606
MEN1	O00255-1.4	P600L	Neutral	0.19
MEN1	O00255-1.4	P600M	Neutral	0.094
MEN1	O00255-1.4	P600N	Neutral	0.045
MEN1	O00255-1.4	P600Q	Neutral	0.084
MEN1	O00255-1.4	P600R	Pathogenic	0.815
MEN1	O00255-1.4	P600S	Neutral	0.039
MEN1	O00255-1.4	P600T	Neutral	0.009
MEN1	O00255-1.4	P600V	Neutral	0.024
MEN1	O00255-1.4	P600W	Pathogenic	0.918
MEN1	O00255-1.4	P600Y	Neutral	0.201
MEN1	O00255-1.4	S601A	Neutral	0.0
MEN1	O00255-1.4	S601C	Neutral	0.002
MEN1	O00255-1.4	S601D	Neutral	0.002
MEN1	O00255-1.4	S601E	Neutral	0.006
MEN1	O00255-1.4	S601F	Neutral	0.255
MEN1	O00255-1.4	S601G	Neutral	0.001
MEN1	O00255-1.4	S601H	Neutral	0.006
MEN1	O00255-1.4	S601I	Neutral	0.133
MEN1	O00255-1.4	S601K	Neutral	0.069
MEN1	O00255-1.4	S601L	Neutral	0.115
MEN1	O00255-1.4	S601M	Neutral	0.054
MEN1	O00255-1.4	S601N	Neutral	0.002
MEN1	O00255-1.4	S601P	Neutral	0.002
MEN1	O00255-1.4	S601Q	Neutral	0.004
MEN1	O00255-1.4	S601R	Neutral	0.174
MEN1	O00255-1.4	S601T	Neutral	0.001
MEN1	O00255-1.4	S601V	Neutral	0.014
MEN1	O00255-1.4	S601W	Pathogenic	0.861
MEN1	O00255-1.4	S601Y	Neutral	0.122
MEN1	O00255-1.4	D602A	Neutral	0.44
MEN1	O00255-1.4	D602C	Neutral	0.376
MEN1	O00255-1.4	D602E	Neutral	0.078
MEN1	O00255-1.4	D602F	Pathogenic	0.976
MEN1	O00255-1.4	D602G	Pathogenic	0.65
MEN1	O00255-1.4	D602H	Neutral	0.41
MEN1	O00255-1.4	D602I	Pathogenic	0.949
MEN1	O00255-1.4	D602K	Neutral	0.45
MEN1	O00255-1.4	D602L	Pathogenic	0.943
MEN1	O00255-1.4	D602M	Pathogenic	0.88
MEN1	O00255-1.4	D602N	Neutral	0.035
MEN1	O00255-1.4	D602P	Neutral	0.205
MEN1	O00255-1.4	D602Q	Neutral	0.215
MEN1	O00255-1.4	D602R	Pathogenic	0.702
MEN1	O00255-1.4	D602S	Neutral	0.203
MEN1	O00255-1.4	D602T	Neutral	0.116
MEN1	O00255-1.4	D602V	Pathogenic	0.633
MEN1	O00255-1.4	D602W	Pathogenic	0.999
MEN1	O00255-1.4	D602Y	Pathogenic	0.944
MEN1	O00255-1.4	Y603A	Pathogenic	0.842
MEN1	O00255-1.4	Y603C	Neutral	0.317
MEN1	O00255-1.4	Y603D	Pathogenic	0.844
MEN1	O00255-1.4	Y603E	Pathogenic	0.517
MEN1	O00255-1.4	Y603F	Neutral	0.032
MEN1	O00255-1.4	Y603G	Pathogenic	0.975
MEN1	O00255-1.4	Y603H	Neutral	0.11
MEN1	O00255-1.4	Y603I	Neutral	0.088
MEN1	O00255-1.4	Y603K	Neutral	0.214
MEN1	O00255-1.4	Y603L	Neutral	0.076
MEN1	O00255-1.4	Y603M	Neutral	0.037
MEN1	O00255-1.4	Y603N	Pathogenic	0.727
MEN1	O00255-1.4	Y603P	Neutral	0.343
MEN1	O00255-1.4	Y603Q	Neutral	0.261
MEN1	O00255-1.4	Y603R	Neutral	0.231
MEN1	O00255-1.4	Y603S	Pathogenic	0.856
MEN1	O00255-1.4	Y603T	Neutral	0.454
MEN1	O00255-1.4	Y603V	Neutral	0.134
MEN1	O00255-1.4	Y603W	Neutral	0.195
MEN1	O00255-1.4	T604A	Neutral	0.007
MEN1	O00255-1.4	T604C	Neutral	0.006
MEN1	O00255-1.4	T604D	Neutral	0.006
MEN1	O00255-1.4	T604E	Neutral	0.014
MEN1	O00255-1.4	T604F	Neutral	0.231
MEN1	O00255-1.4	T604G	Neutral	0.045
MEN1	O00255-1.4	T604H	Neutral	0.009
MEN1	O00255-1.4	T604I	Neutral	0.113
MEN1	O00255-1.4	T604K	Neutral	0.151
MEN1	O00255-1.4	T604L	Neutral	0.097
MEN1	O00255-1.4	T604M	Neutral	0.048
MEN1	O00255-1.4	T604N	Neutral	0.005
MEN1	O00255-1.4	T604P	Neutral	0.003
MEN1	O00255-1.4	T604Q	Neutral	0.011
MEN1	O00255-1.4	T604R	Neutral	0.324
MEN1	O00255-1.4	T604S	Neutral	0.006
MEN1	O00255-1.4	T604V	Neutral	0.011
MEN1	O00255-1.4	T604W	Pathogenic	0.837
MEN1	O00255-1.4	T604Y	Neutral	0.109
MEN1	O00255-1.4	L605A	Neutral	0.068
MEN1	O00255-1.4	L605C	Neutral	0.006
MEN1	O00255-1.4	L605D	Neutral	0.077
MEN1	O00255-1.4	L605E	Neutral	0.016
MEN1	O00255-1.4	L605F	Neutral	0.0
MEN1	O00255-1.4	L605G	Neutral	0.373
MEN1	O00255-1.4	L605H	Neutral	0.002
MEN1	O00255-1.4	L605I	Neutral	0.0
MEN1	O00255-1.4	L605K	Neutral	0.02
MEN1	O00255-1.4	L605M	Neutral	0.0
MEN1	O00255-1.4	L605N	Neutral	0.04
MEN1	O00255-1.4	L605P	Neutral	0.008
MEN1	O00255-1.4	L605Q	Neutral	0.005
MEN1	O00255-1.4	L605R	Neutral	0.052
MEN1	O00255-1.4	L605S	Neutral	0.08
MEN1	O00255-1.4	L605T	Neutral	0.011
MEN1	O00255-1.4	L605V	Neutral	0.001
MEN1	O00255-1.4	L605W	Neutral	0.005
MEN1	O00255-1.4	L605Y	Neutral	0.001
MEN1	O00255-1.4	S606A	Neutral	0.001
MEN1	O00255-1.4	S606C	Neutral	0.005
MEN1	O00255-1.4	S606D	Neutral	0.004
MEN1	O00255-1.4	S606E	Neutral	0.013
MEN1	O00255-1.4	S606F	Neutral	0.426
MEN1	O00255-1.4	S606G	Neutral	0.002
MEN1	O00255-1.4	S606H	Neutral	0.013
MEN1	O00255-1.4	S606I	Neutral	0.25
MEN1	O00255-1.4	S606K	Neutral	0.138
MEN1	O00255-1.4	S606L	Neutral	0.22
MEN1	O00255-1.4	S606M	Neutral	0.111
MEN1	O00255-1.4	S606N	Neutral	0.004
MEN1	O00255-1.4	S606P	Neutral	0.004
MEN1	O00255-1.4	S606Q	Neutral	0.009
MEN1	O00255-1.4	S606R	Neutral	0.314
MEN1	O00255-1.4	S606T	Neutral	0.002
MEN1	O00255-1.4	S606V	Neutral	0.03
MEN1	O00255-1.4	S606W	Pathogenic	0.931
MEN1	O00255-1.4	S606Y	Neutral	0.232
MEN1	O00255-1.4	F607A	Pathogenic	0.966
MEN1	O00255-1.4	F607C	Pathogenic	0.698
MEN1	O00255-1.4	F607D	Pathogenic	0.967
MEN1	O00255-1.4	F607E	Pathogenic	0.859
MEN1	O00255-1.4	F607G	Pathogenic	0.995
MEN1	O00255-1.4	F607H	Neutral	0.442
MEN1	O00255-1.4	F607I	Neutral	0.032
MEN1	O00255-1.4	F607K	Pathogenic	0.608
MEN1	O00255-1.4	F607L	Neutral	0.036
MEN1	O00255-1.4	F607M	Neutral	0.074
MEN1	O00255-1.4	F607N	Pathogenic	0.938
MEN1	O00255-1.4	F607P	Pathogenic	0.748
MEN1	O00255-1.4	F607Q	Pathogenic	0.681
MEN1	O00255-1.4	F607R	Pathogenic	0.807
MEN1	O00255-1.4	F607S	Pathogenic	0.97
MEN1	O00255-1.4	F607T	Pathogenic	0.816
MEN1	O00255-1.4	F607V	Neutral	0.265
MEN1	O00255-1.4	F607W	Neutral	0.187
MEN1	O00255-1.4	F607Y	Neutral	0.067
MEN1	O00255-1.4	L608A	Neutral	0.078
MEN1	O00255-1.4	L608C	Neutral	0.007
MEN1	O00255-1.4	L608D	Neutral	0.088
MEN1	O00255-1.4	L608E	Neutral	0.019
MEN1	O00255-1.4	L608F	Neutral	0.0
MEN1	O00255-1.4	L608G	Neutral	0.408
MEN1	O00255-1.4	L608H	Neutral	0.003
MEN1	O00255-1.4	L608I	Neutral	0.0
MEN1	O00255-1.4	L608K	Neutral	0.023
MEN1	O00255-1.4	L608M	Neutral	0.0
MEN1	O00255-1.4	L608N	Neutral	0.045
MEN1	O00255-1.4	L608P	Neutral	0.009
MEN1	O00255-1.4	L608Q	Neutral	0.006
MEN1	O00255-1.4	L608R	Neutral	0.06
MEN1	O00255-1.4	L608S	Neutral	0.091
MEN1	O00255-1.4	L608T	Neutral	0.013
MEN1	O00255-1.4	L608V	Neutral	0.001
MEN1	O00255-1.4	L608W	Neutral	0.006
MEN1	O00255-1.4	L608Y	Neutral	0.001
MEN1	O00255-1.4	K609A	Pathogenic	0.886
MEN1	O00255-1.4	K609C	Pathogenic	0.863
MEN1	O00255-1.4	K609D	Neutral	0.183
MEN1	O00255-1.4	K609E	Neutral	0.06
MEN1	O00255-1.4	K609F	Neutral	0.376
MEN1	O00255-1.4	K609G	Pathogenic	0.954
MEN1	O00255-1.4	K609H	Neutral	0.114
MEN1	O00255-1.4	K609I	Pathogenic	0.583
MEN1	O00255-1.4	K609L	Pathogenic	0.527
MEN1	O00255-1.4	K609M	Neutral	0.329
MEN1	O00255-1.4	K609N	Neutral	0.161
MEN1	O00255-1.4	K609P	Pathogenic	0.73
MEN1	O00255-1.4	K609Q	Neutral	0.08
MEN1	O00255-1.4	K609R	Neutral	0.013
MEN1	O00255-1.4	K609S	Pathogenic	0.727
MEN1	O00255-1.4	K609T	Pathogenic	0.506
MEN1	O00255-1.4	K609V	Pathogenic	0.678
MEN1	O00255-1.4	K609W	Pathogenic	0.911
MEN1	O00255-1.4	K609Y	Neutral	0.188
MEN1	O00255-1.4	R610A	Pathogenic	0.997
MEN1	O00255-1.4	R610C	Pathogenic	0.997
MEN1	O00255-1.4	R610D	Pathogenic	0.917
MEN1	O00255-1.4	R610E	Pathogenic	0.76
MEN1	O00255-1.4	R610F	Pathogenic	0.965
MEN1	O00255-1.4	R610G	Pathogenic	0.999
MEN1	O00255-1.4	R610H	Pathogenic	0.849
MEN1	O00255-1.4	R610I	Pathogenic	0.985
MEN1	O00255-1.4	R610K	Neutral	0.185
MEN1	O00255-1.4	R610L	Pathogenic	0.981
MEN1	O00255-1.4	R610M	Pathogenic	0.958
MEN1	O00255-1.4	R610N	Pathogenic	0.899
MEN1	O00255-1.4	R610P	Pathogenic	0.993
MEN1	O00255-1.4	R610Q	Pathogenic	0.802
MEN1	O00255-1.4	R610S	Pathogenic	0.992
MEN1	O00255-1.4	R610T	Pathogenic	0.979
MEN1	O00255-1.4	R610V	Pathogenic	0.99
MEN1	O00255-1.4	R610W	Pathogenic	0.986
MEN1	O00255-1.4	R610Y	Pathogenic	0.814
MEN1	O00255-1.4	Q611A	Neutral	0.069
MEN1	O00255-1.4	Q611C	Neutral	0.057
MEN1	O00255-1.4	Q611D	Neutral	0.012
MEN1	O00255-1.4	Q611E	Neutral	0.002
MEN1	O00255-1.4	Q611F	Neutral	0.117
MEN1	O00255-1.4	Q611G	Neutral	0.164
MEN1	O00255-1.4	Q611H	Neutral	0.002
MEN1	O00255-1.4	Q611I	Neutral	0.056
MEN1	O00255-1.4	Q611K	Neutral	0.014
MEN1	O00255-1.4	Q611L	Neutral	0.045
MEN1	O00255-1.4	Q611M	Neutral	0.019
MEN1	O00255-1.4	Q611N	Neutral	0.006
MEN1	O00255-1.4	Q611P	Neutral	0.025
MEN1	O00255-1.4	Q611R	Neutral	0.036
MEN1	O00255-1.4	Q611S	Neutral	0.025
MEN1	O00255-1.4	Q611T	Neutral	0.01
MEN1	O00255-1.4	Q611V	Neutral	0.02
MEN1	O00255-1.4	Q611W	Pathogenic	0.68
MEN1	O00255-1.4	Q611Y	Neutral	0.046
MEN1	O00255-1.4	R612A	Pathogenic	0.989
MEN1	O00255-1.4	R612C	Pathogenic	0.987
MEN1	O00255-1.4	R612D	Pathogenic	0.737
MEN1	O00255-1.4	R612E	Neutral	0.445
MEN1	O00255-1.4	R612F	Pathogenic	0.876
MEN1	O00255-1.4	R612G	Pathogenic	0.996
MEN1	O00255-1.4	R612H	Pathogenic	0.587
MEN1	O00255-1.4	R612I	Pathogenic	0.943
MEN1	O00255-1.4	R612K	Neutral	0.054
MEN1	O00255-1.4	R612L	Pathogenic	0.929
MEN1	O00255-1.4	R612M	Pathogenic	0.852
MEN1	O00255-1.4	R612N	Pathogenic	0.692
MEN1	O00255-1.4	R612P	Pathogenic	0.971
MEN1	O00255-1.4	R612Q	Pathogenic	0.505
MEN1	O00255-1.4	R612S	Pathogenic	0.971
MEN1	O00255-1.4	R612T	Pathogenic	0.923
MEN1	O00255-1.4	R612V	Pathogenic	0.963
MEN1	O00255-1.4	R612W	Pathogenic	0.945
MEN1	O00255-1.4	R612Y	Pathogenic	0.525
MEN1	O00255-1.4	K613A	Pathogenic	0.906
MEN1	O00255-1.4	K613C	Pathogenic	0.887
MEN1	O00255-1.4	K613D	Neutral	0.219
MEN1	O00255-1.4	K613E	Neutral	0.074
MEN1	O00255-1.4	K613F	Neutral	0.429
MEN1	O00255-1.4	K613G	Pathogenic	0.963
MEN1	O00255-1.4	K613H	Neutral	0.139
MEN1	O00255-1.4	K613I	Pathogenic	0.636
MEN1	O00255-1.4	K613L	Pathogenic	0.582
MEN1	O00255-1.4	K613M	Neutral	0.38
MEN1	O00255-1.4	K613N	Neutral	0.193
MEN1	O00255-1.4	K613P	Pathogenic	0.772
MEN1	O00255-1.4	K613Q	Neutral	0.098
MEN1	O00255-1.4	K613R	Neutral	0.016
MEN1	O00255-1.4	K613S	Pathogenic	0.769
MEN1	O00255-1.4	K613T	Pathogenic	0.561
MEN1	O00255-1.4	K613V	Pathogenic	0.724
MEN1	O00255-1.4	K613W	Pathogenic	0.928
MEN1	O00255-1.4	K613Y	Neutral	0.224
MEN1	O00255-1.4	G614A	Neutral	0.017
MEN1	O00255-1.4	G614C	Neutral	0.206
MEN1	O00255-1.4	G614D	Neutral	0.192
MEN1	O00255-1.4	G614E	Neutral	0.438
MEN1	O00255-1.4	G614F	Pathogenic	0.974
MEN1	O00255-1.4	G614H	Neutral	0.402
MEN1	O00255-1.4	G614I	Pathogenic	0.947
MEN1	O00255-1.4	G614K	Pathogenic	0.906
MEN1	O00255-1.4	G614L	Pathogenic	0.938
MEN1	O00255-1.4	G614M	Pathogenic	0.869
MEN1	O00255-1.4	G614N	Neutral	0.198
MEN1	O00255-1.4	G614P	Neutral	0.177
MEN1	O00255-1.4	G614Q	Neutral	0.365
MEN1	O00255-1.4	G614R	Pathogenic	0.963
MEN1	O00255-1.4	G614S	Neutral	0.017
MEN1	O00255-1.4	G614T	Neutral	0.113
MEN1	O00255-1.4	G614V	Pathogenic	0.611
MEN1	O00255-1.4	G614W	Pathogenic	0.998
MEN1	O00255-1.4	G614Y	Pathogenic	0.938
MEN1	O00255-1.4	L615A	Pathogenic	0.833
MEN1	O00255-1.4	L615C	Neutral	0.288
MEN1	O00255-1.4	L615D	Pathogenic	0.851
MEN1	O00255-1.4	L615E	Pathogenic	0.532
MEN1	O00255-1.4	L615F	Neutral	0.018
MEN1	O00255-1.4	L615G	Pathogenic	0.976
MEN1	O00255-1.4	L615H	Neutral	0.143
MEN1	O00255-1.4	L615I	Neutral	0.007
MEN1	O00255-1.4	L615K	Pathogenic	0.584
MEN1	O00255-1.4	L615M	Neutral	0.013
MEN1	O00255-1.4	L615N	Pathogenic	0.739
MEN1	O00255-1.4	L615P	Neutral	0.342
MEN1	O00255-1.4	L615Q	Neutral	0.272
MEN1	O00255-1.4	L615R	Pathogenic	0.791
MEN1	O00255-1.4	L615S	Pathogenic	0.856
MEN1	O00255-1.4	L615T	Neutral	0.438
MEN1	O00255-1.4	L615V	Neutral	0.056
MEN1	O00255-1.4	L615W	Neutral	0.261
MEN1	O00255-1.4	L615Y	Neutral	0.08
NPC1	O15118-1.2	M1A	Neutral	0.104
NPC1	O15118-1.2	M1C	Neutral	0.115
NPC1	O15118-1.2	M1D	Neutral	0.132
NPC1	O15118-1.2	M1E	Neutral	0.088
NPC1	O15118-1.2	M1F	Neutral	0.063
NPC1	O15118-1.2	M1G	Neutral	0.203
NPC1	O15118-1.2	M1H	Neutral	0.106
NPC1	O15118-1.2	M1I	Neutral	0.041
NPC1	O15118-1.2	M1K	Neutral	0.054
NPC1	O15118-1.2	M1L	Neutral	0.029
NPC1	O15118-1.2	M1N	Neutral	0.096
NPC1	O15118-1.2	M1P	Neutral	0.146
NPC1	O15118-1.2	M1Q	Neutral	0.047
NPC1	O15118-1.2	M1R	Neutral	0.058
NPC1	O15118-1.2	M1S	Neutral	0.091
NPC1	O15118-1.2	M1T	Neutral	0.089
NPC1	O15118-1.2	M1V	Neutral	0.055
NPC1	O15118-1.2	M1W	Neutral	0.092
NPC1	O15118-1.2	M1Y	Neutral	0.102
NPC1	O15118-1.2	T2A	Neutral	0.02
NPC1	O15118-1.2	T2C	Neutral	0.021
NPC1	O15118-1.2	T2D	Neutral	0.019
NPC1	O15118-1.2	T2E	Neutral	0.021
NPC1	O15118-1.2	T2F	Neutral	0.029
NPC1	O15118-1.2	T2G	Neutral	0.045
NPC1	O15118-1.2	T2H	Neutral	0.041
NPC1	O15118-1.2	T2I	Neutral	0.019
NPC1	O15118-1.2	T2K	Neutral	0.022
NPC1	O15118-1.2	T2L	Neutral	0.019
NPC1	O15118-1.2	T2M	Neutral	0.022
NPC1	O15118-1.2	T2N	Neutral	0.013
NPC1	O15118-1.2	T2P	Neutral	0.022
NPC1	O15118-1.2	T2Q	Neutral	0.025
NPC1	O15118-1.2	T2R	Neutral	0.024
NPC1	O15118-1.2	T2S	Neutral	0.012
NPC1	O15118-1.2	T2V	Neutral	0.014
NPC1	O15118-1.2	T2W	Neutral	0.03
NPC1	O15118-1.2	T2Y	Neutral	0.039
NPC1	O15118-1.2	A3C	Neutral	0.019
NPC1	O15118-1.2	A3D	Neutral	0.036
NPC1	O15118-1.2	A3E	Neutral	0.029
NPC1	O15118-1.2	A3F	Neutral	0.041
NPC1	O15118-1.2	A3G	Neutral	0.021
NPC1	O15118-1.2	A3H	Neutral	0.057
NPC1	O15118-1.2	A3I	Neutral	0.027
NPC1	O15118-1.2	A3K	Neutral	0.03
NPC1	O15118-1.2	A3L	Neutral	0.027
NPC1	O15118-1.2	A3M	Neutral	0.032
NPC1	O15118-1.2	A3N	Neutral	0.039
NPC1	O15118-1.2	A3P	Neutral	0.031
NPC1	O15118-1.2	A3Q	Neutral	0.034
NPC1	O15118-1.2	A3R	Neutral	0.032
NPC1	O15118-1.2	A3S	Neutral	0.013
NPC1	O15118-1.2	A3T	Neutral	0.024
NPC1	O15118-1.2	A3V	Neutral	0.02
NPC1	O15118-1.2	A3W	Neutral	0.06
NPC1	O15118-1.2	A3Y	Neutral	0.055
NPC1	O15118-1.2	R4A	Neutral	0.142
NPC1	O15118-1.2	R4C	Neutral	0.203
NPC1	O15118-1.2	R4D	Neutral	0.232
NPC1	O15118-1.2	R4E	Neutral	0.107
NPC1	O15118-1.2	R4F	Neutral	0.127
NPC1	O15118-1.2	R4G	Neutral	0.232
NPC1	O15118-1.2	R4H	Neutral	0.081
NPC1	O15118-1.2	R4I	Neutral	0.134
NPC1	O15118-1.2	R4K	Neutral	0.05
NPC1	O15118-1.2	R4L	Neutral	0.098
NPC1	O15118-1.2	R4M	Neutral	0.079
NPC1	O15118-1.2	R4N	Neutral	0.113
NPC1	O15118-1.2	R4P	Neutral	0.156
NPC1	O15118-1.2	R4Q	Neutral	0.064
NPC1	O15118-1.2	R4S	Neutral	0.152
NPC1	O15118-1.2	R4T	Neutral	0.126
NPC1	O15118-1.2	R4V	Neutral	0.174
NPC1	O15118-1.2	R4W	Neutral	0.112
NPC1	O15118-1.2	R4Y	Neutral	0.111
NPC1	O15118-1.2	G5A	Neutral	0.108
NPC1	O15118-1.2	G5C	Neutral	0.257
NPC1	O15118-1.2	G5D	Neutral	0.151
NPC1	O15118-1.2	G5E	Neutral	0.233
NPC1	O15118-1.2	G5F	Neutral	0.263
NPC1	O15118-1.2	G5H	Neutral	0.275
NPC1	O15118-1.2	G5I	Neutral	0.328
NPC1	O15118-1.2	G5K	Neutral	0.24
NPC1	O15118-1.2	G5L	Neutral	0.336
NPC1	O15118-1.2	G5M	Neutral	0.286
NPC1	O15118-1.2	G5N	Neutral	0.116
NPC1	O15118-1.2	G5P	Neutral	0.209
NPC1	O15118-1.2	G5Q	Neutral	0.264
NPC1	O15118-1.2	G5R	Neutral	0.254
NPC1	O15118-1.2	G5S	Neutral	0.121
NPC1	O15118-1.2	G5T	Neutral	0.238
NPC1	O15118-1.2	G5V	Neutral	0.264
NPC1	O15118-1.2	G5W	Neutral	0.198
NPC1	O15118-1.2	G5Y	Neutral	0.327
NPC1	O15118-1.2	L6A	Neutral	0.076
NPC1	O15118-1.2	L6C	Neutral	0.084
NPC1	O15118-1.2	L6D	Neutral	0.136
NPC1	O15118-1.2	L6E	Neutral	0.091
NPC1	O15118-1.2	L6F	Neutral	0.061
NPC1	O15118-1.2	L6G	Neutral	0.209
NPC1	O15118-1.2	L6H	Neutral	0.11
NPC1	O15118-1.2	L6I	Neutral	0.027
NPC1	O15118-1.2	L6K	Neutral	0.056
NPC1	O15118-1.2	L6M	Neutral	0.024
NPC1	O15118-1.2	L6N	Neutral	0.099
NPC1	O15118-1.2	L6P	Neutral	0.151
NPC1	O15118-1.2	L6Q	Neutral	0.071
NPC1	O15118-1.2	L6R	Neutral	0.06
NPC1	O15118-1.2	L6S	Neutral	0.094
NPC1	O15118-1.2	L6T	Neutral	0.065
NPC1	O15118-1.2	L6V	Neutral	0.039
NPC1	O15118-1.2	L6W	Neutral	0.125
NPC1	O15118-1.2	L6Y	Neutral	0.074
NPC1	O15118-1.2	A7C	Neutral	0.056
NPC1	O15118-1.2	A7D	Neutral	0.104
NPC1	O15118-1.2	A7E	Neutral	0.084
NPC1	O15118-1.2	A7F	Neutral	0.117
NPC1	O15118-1.2	A7G	Neutral	0.063
NPC1	O15118-1.2	A7H	Neutral	0.156
NPC1	O15118-1.2	A7I	Neutral	0.078
NPC1	O15118-1.2	A7K	Neutral	0.088
NPC1	O15118-1.2	A7L	Neutral	0.08
NPC1	O15118-1.2	A7M	Neutral	0.092
NPC1	O15118-1.2	A7N	Neutral	0.113
NPC1	O15118-1.2	A7P	Neutral	0.089
NPC1	O15118-1.2	A7Q	Neutral	0.099
NPC1	O15118-1.2	A7R	Neutral	0.094
NPC1	O15118-1.2	A7S	Neutral	0.04
NPC1	O15118-1.2	A7T	Neutral	0.071
NPC1	O15118-1.2	A7V	Neutral	0.058
NPC1	O15118-1.2	A7W	Neutral	0.166
NPC1	O15118-1.2	A7Y	Neutral	0.154
NPC1	O15118-1.2	L8A	Neutral	0.115
NPC1	O15118-1.2	L8C	Neutral	0.126
NPC1	O15118-1.2	L8D	Neutral	0.2
NPC1	O15118-1.2	L8E	Neutral	0.137
NPC1	O15118-1.2	L8F	Neutral	0.093
NPC1	O15118-1.2	L8G	Neutral	0.295
NPC1	O15118-1.2	L8H	Neutral	0.163
NPC1	O15118-1.2	L8I	Neutral	0.042
NPC1	O15118-1.2	L8K	Neutral	0.086
NPC1	O15118-1.2	L8M	Neutral	0.038
NPC1	O15118-1.2	L8N	Neutral	0.148
NPC1	O15118-1.2	L8P	Neutral	0.219
NPC1	O15118-1.2	L8Q	Neutral	0.108
NPC1	O15118-1.2	L8R	Neutral	0.092
NPC1	O15118-1.2	L8S	Neutral	0.141
NPC1	O15118-1.2	L8T	Neutral	0.098
NPC1	O15118-1.2	L8V	Neutral	0.061
NPC1	O15118-1.2	L8W	Neutral	0.185
NPC1	O15118-1.2	L8Y	Neutral	0.112
NPC1	O15118-1.2	G9A	Neutral	0.111
NPC1	O15118-1.2	G9C	Neutral	0.262
NPC1	O15118-1.2	G9D	Neutral	0.154
NPC1	O15118-1.2	G9E	Neutral	0.237
NPC1	O15118-1.2	G9F	Neutral	0.267
NPC1	O15118-1.2	G9H	Neutral	0.28
NPC1	O15118-1.2	G9I	Neutral	0.333
NPC1	O15118-1.2	G9K	Neutral	0.245
NPC1	O15118-1.2	G9L	Neutral	0.341
NPC1	O15118-1.2	G9M	Neutral	0.291
NPC1	O15118-1.2	G9N	Neutral	0.119
NPC1	O15118-1.2	G9P	Neutral	0.212
NPC1	O15118-1.2	G9Q	Neutral	0.269
NPC1	O15118-1.2	G9R	Neutral	0.258
NPC1	O15118-1.2	G9S	Neutral	0.124
NPC1	O15118-1.2	G9T	Neutral	0.243
NPC1	O15118-1.2	G9V	Neutral	0.269
NPC1	O15118-1.2	G9W	Neutral	0.201
NPC1	O15118-1.2	G9Y	Neutral	0.333
NPC1	O15118-1.2	L10A	Neutral	0.378
NPC1	O15118-1.2	L10C	Neutral	0.404
NPC1	O15118-1.2	L10D	Pathogenic	0.539
NPC1	O15118-1.2	L10E	Neutral	0.427
NPC1	O15118-1.2	L10F	Neutral	0.326
NPC1	O15118-1.2	L10G	Pathogenic	0.662
NPC1	O15118-1.2	L10H	Neutral	0.477
NPC1	O15118-1.2	L10I	Neutral	0.172
NPC1	O15118-1.2	L10K	Neutral	0.305
NPC1	O15118-1.2	L10M	Neutral	0.155
NPC1	O15118-1.2	L10N	Neutral	0.449
NPC1	O15118-1.2	L10P	Pathogenic	0.567
NPC1	O15118-1.2	L10Q	Neutral	0.361
NPC1	O15118-1.2	L10R	Neutral	0.321
NPC1	O15118-1.2	L10S	Neutral	0.435
NPC1	O15118-1.2	L10T	Neutral	0.338
NPC1	O15118-1.2	L10V	Neutral	0.232
NPC1	O15118-1.2	L10W	Pathogenic	0.515
NPC1	O15118-1.2	L10Y	Neutral	0.372
NPC1	O15118-1.2	L11A	Neutral	0.441
NPC1	O15118-1.2	L11C	Neutral	0.468
NPC1	O15118-1.2	L11D	Pathogenic	0.603
NPC1	O15118-1.2	L11E	Neutral	0.492
NPC1	O15118-1.2	L11F	Neutral	0.386
NPC1	O15118-1.2	L11G	Pathogenic	0.718
NPC1	O15118-1.2	L11H	Pathogenic	0.542
NPC1	O15118-1.2	L11I	Neutral	0.213
NPC1	O15118-1.2	L11K	Neutral	0.364
NPC1	O15118-1.2	L11M	Neutral	0.193
NPC1	O15118-1.2	L11N	Pathogenic	0.515
NPC1	O15118-1.2	L11P	Pathogenic	0.63
NPC1	O15118-1.2	L11Q	Neutral	0.423
NPC1	O15118-1.2	L11R	Neutral	0.381
NPC1	O15118-1.2	L11S	Neutral	0.5
NPC1	O15118-1.2	L11T	Neutral	0.399
NPC1	O15118-1.2	L11V	Neutral	0.282
NPC1	O15118-1.2	L11W	Pathogenic	0.58
NPC1	O15118-1.2	L11Y	Neutral	0.435
NPC1	O15118-1.2	L12A	Neutral	0.111
NPC1	O15118-1.2	L12C	Neutral	0.123
NPC1	O15118-1.2	L12D	Neutral	0.194
NPC1	O15118-1.2	L12E	Neutral	0.133
NPC1	O15118-1.2	L12F	Neutral	0.091
NPC1	O15118-1.2	L12G	Neutral	0.288
NPC1	O15118-1.2	L12H	Neutral	0.158
NPC1	O15118-1.2	L12I	Neutral	0.041
NPC1	O15118-1.2	L12K	Neutral	0.083
NPC1	O15118-1.2	L12M	Neutral	0.037
NPC1	O15118-1.2	L12N	Neutral	0.144
NPC1	O15118-1.2	L12P	Neutral	0.213
NPC1	O15118-1.2	L12Q	Neutral	0.104
NPC1	O15118-1.2	L12R	Neutral	0.089
NPC1	O15118-1.2	L12S	Neutral	0.137
NPC1	O15118-1.2	L12T	Neutral	0.095
NPC1	O15118-1.2	L12V	Neutral	0.059
NPC1	O15118-1.2	L12W	Neutral	0.18
NPC1	O15118-1.2	L12Y	Neutral	0.109
NPC1	O15118-1.2	L13A	Neutral	0.095
NPC1	O15118-1.2	L13C	Neutral	0.105
NPC1	O15118-1.2	L13D	Neutral	0.168
NPC1	O15118-1.2	L13E	Neutral	0.114
NPC1	O15118-1.2	L13F	Neutral	0.077
NPC1	O15118-1.2	L13G	Neutral	0.253
NPC1	O15118-1.2	L13H	Neutral	0.136
NPC1	O15118-1.2	L13I	Neutral	0.035
NPC1	O15118-1.2	L13K	Neutral	0.071
NPC1	O15118-1.2	L13M	Neutral	0.031
NPC1	O15118-1.2	L13N	Neutral	0.124
NPC1	O15118-1.2	L13P	Neutral	0.185
NPC1	O15118-1.2	L13Q	Neutral	0.089
NPC1	O15118-1.2	L13R	Neutral	0.076
NPC1	O15118-1.2	L13S	Neutral	0.117
NPC1	O15118-1.2	L13T	Neutral	0.081
NPC1	O15118-1.2	L13V	Neutral	0.05
NPC1	O15118-1.2	L13W	Neutral	0.155
NPC1	O15118-1.2	L13Y	Neutral	0.093
NPC1	O15118-1.2	L14A	Neutral	0.152
NPC1	O15118-1.2	L14C	Neutral	0.167
NPC1	O15118-1.2	L14D	Neutral	0.257
NPC1	O15118-1.2	L14E	Neutral	0.181
NPC1	O15118-1.2	L14F	Neutral	0.125
NPC1	O15118-1.2	L14G	Neutral	0.367
NPC1	O15118-1.2	L14H	Neutral	0.212
NPC1	O15118-1.2	L14I	Neutral	0.058
NPC1	O15118-1.2	L14K	Neutral	0.115
NPC1	O15118-1.2	L14M	Neutral	0.052
NPC1	O15118-1.2	L14N	Neutral	0.194
NPC1	O15118-1.2	L14P	Neutral	0.279
NPC1	O15118-1.2	L14Q	Neutral	0.143
NPC1	O15118-1.2	L14R	Neutral	0.123
NPC1	O15118-1.2	L14S	Neutral	0.185
NPC1	O15118-1.2	L14T	Neutral	0.131
NPC1	O15118-1.2	L14V	Neutral	0.082
NPC1	O15118-1.2	L14W	Neutral	0.239
NPC1	O15118-1.2	L14Y	Neutral	0.149
NPC1	O15118-1.2	L15A	Neutral	0.07
NPC1	O15118-1.2	L15C	Neutral	0.078
NPC1	O15118-1.2	L15D	Neutral	0.127
NPC1	O15118-1.2	L15E	Neutral	0.085
NPC1	O15118-1.2	L15F	Neutral	0.057
NPC1	O15118-1.2	L15G	Neutral	0.196
NPC1	O15118-1.2	L15H	Neutral	0.102
NPC1	O15118-1.2	L15I	Neutral	0.025
NPC1	O15118-1.2	L15K	Neutral	0.052
NPC1	O15118-1.2	L15M	Neutral	0.022
NPC1	O15118-1.2	L15N	Neutral	0.092
NPC1	O15118-1.2	L15P	Neutral	0.14
NPC1	O15118-1.2	L15Q	Neutral	0.066
NPC1	O15118-1.2	L15R	Neutral	0.056
NPC1	O15118-1.2	L15S	Neutral	0.087
NPC1	O15118-1.2	L15T	Neutral	0.06
NPC1	O15118-1.2	L15V	Neutral	0.036
NPC1	O15118-1.2	L15W	Neutral	0.116
NPC1	O15118-1.2	L15Y	Neutral	0.069
NPC1	O15118-1.2	C16A	Neutral	0.051
NPC1	O15118-1.2	C16D	Neutral	0.098
NPC1	O15118-1.2	C16E	Neutral	0.158
NPC1	O15118-1.2	C16F	Neutral	0.117
NPC1	O15118-1.2	C16G	Neutral	0.147
NPC1	O15118-1.2	C16H	Neutral	0.148
NPC1	O15118-1.2	C16I	Neutral	0.078
NPC1	O15118-1.2	C16K	Neutral	0.117
NPC1	O15118-1.2	C16L	Neutral	0.08
NPC1	O15118-1.2	C16M	Neutral	0.092
NPC1	O15118-1.2	C16N	Neutral	0.106
NPC1	O15118-1.2	C16P	Neutral	0.151
NPC1	O15118-1.2	C16Q	Neutral	0.131
NPC1	O15118-1.2	C16R	Neutral	0.125
NPC1	O15118-1.2	C16S	Neutral	0.063
NPC1	O15118-1.2	C16T	Neutral	0.067
NPC1	O15118-1.2	C16V	Neutral	0.083
NPC1	O15118-1.2	C16W	Neutral	0.119
NPC1	O15118-1.2	C16Y	Neutral	0.152
NPC1	O15118-1.2	P17A	Neutral	0.088
NPC1	O15118-1.2	P17C	Neutral	0.164
NPC1	O15118-1.2	P17D	Neutral	0.056
NPC1	O15118-1.2	P17E	Neutral	0.065
NPC1	O15118-1.2	P17F	Neutral	0.221
NPC1	O15118-1.2	P17G	Neutral	0.126
NPC1	O15118-1.2	P17H	Neutral	0.122
NPC1	O15118-1.2	P17I	Neutral	0.152
NPC1	O15118-1.2	P17K	Neutral	0.067
NPC1	O15118-1.2	P17L	Neutral	0.157
NPC1	O15118-1.2	P17M	Neutral	0.128
NPC1	O15118-1.2	P17N	Neutral	0.087
NPC1	O15118-1.2	P17Q	Neutral	0.076
NPC1	O15118-1.2	P17R	Neutral	0.102
NPC1	O15118-1.2	P17S	Neutral	0.077
NPC1	O15118-1.2	P17T	Neutral	0.078
NPC1	O15118-1.2	P17V	Neutral	0.117
NPC1	O15118-1.2	P17W	Neutral	0.223
NPC1	O15118-1.2	P17Y	Neutral	0.208
NPC1	O15118-1.2	A18C	Neutral	0.106
NPC1	O15118-1.2	A18D	Neutral	0.187
NPC1	O15118-1.2	A18E	Neutral	0.154
NPC1	O15118-1.2	A18F	Neutral	0.208
NPC1	O15118-1.2	A18G	Neutral	0.118
NPC1	O15118-1.2	A18H	Neutral	0.268
NPC1	O15118-1.2	A18I	Neutral	0.143
NPC1	O15118-1.2	A18K	Neutral	0.16
NPC1	O15118-1.2	A18L	Neutral	0.147
NPC1	O15118-1.2	A18M	Neutral	0.168
NPC1	O15118-1.2	A18N	Neutral	0.201
NPC1	O15118-1.2	A18P	Neutral	0.163
NPC1	O15118-1.2	A18Q	Neutral	0.178
NPC1	O15118-1.2	A18R	Neutral	0.17
NPC1	O15118-1.2	A18S	Neutral	0.076
NPC1	O15118-1.2	A18T	Neutral	0.132
NPC1	O15118-1.2	A18V	Neutral	0.109
NPC1	O15118-1.2	A18W	Neutral	0.282
NPC1	O15118-1.2	A18Y	Neutral	0.264
NPC1	O15118-1.2	Q19A	Neutral	0.173
NPC1	O15118-1.2	Q19C	Neutral	0.244
NPC1	O15118-1.2	Q19D	Neutral	0.109
NPC1	O15118-1.2	Q19E	Neutral	0.05
NPC1	O15118-1.2	Q19F	Neutral	0.192
NPC1	O15118-1.2	Q19G	Neutral	0.277
NPC1	O15118-1.2	Q19H	Neutral	0.104
NPC1	O15118-1.2	Q19I	Neutral	0.181
NPC1	O15118-1.2	Q19K	Neutral	0.071
NPC1	O15118-1.2	Q19L	Neutral	0.134
NPC1	O15118-1.2	Q19M	Neutral	0.077
NPC1	O15118-1.2	Q19N	Neutral	0.112
NPC1	O15118-1.2	Q19P	Neutral	0.137
NPC1	O15118-1.2	Q19R	Neutral	0.076
NPC1	O15118-1.2	Q19S	Neutral	0.134
NPC1	O15118-1.2	Q19T	Neutral	0.154
NPC1	O15118-1.2	Q19V	Neutral	0.153
NPC1	O15118-1.2	Q19W	Neutral	0.141
NPC1	O15118-1.2	Q19Y	Neutral	0.13
NPC1	O15118-1.2	V20A	Neutral	0.146
NPC1	O15118-1.2	V20C	Neutral	0.219
NPC1	O15118-1.2	V20D	Neutral	0.248
NPC1	O15118-1.2	V20E	Neutral	0.18
NPC1	O15118-1.2	V20F	Neutral	0.211
NPC1	O15118-1.2	V20G	Neutral	0.355
NPC1	O15118-1.2	V20H	Neutral	0.306
NPC1	O15118-1.2	V20I	Neutral	0.051
NPC1	O15118-1.2	V20K	Neutral	0.186
NPC1	O15118-1.2	V20L	Neutral	0.107
NPC1	O15118-1.2	V20M	Neutral	0.122
NPC1	O15118-1.2	V20N	Neutral	0.252
NPC1	O15118-1.2	V20P	Neutral	0.27
NPC1	O15118-1.2	V20Q	Neutral	0.207
NPC1	O15118-1.2	V20R	Neutral	0.266
NPC1	O15118-1.2	V20S	Neutral	0.241
NPC1	O15118-1.2	V20T	Neutral	0.126
NPC1	O15118-1.2	V20W	Neutral	0.371
NPC1	O15118-1.2	V20Y	Neutral	0.236
NPC1	O15118-1.2	F21A	Neutral	0.089
NPC1	O15118-1.2	F21C	Neutral	0.098
NPC1	O15118-1.2	F21D	Neutral	0.08
NPC1	O15118-1.2	F21E	Neutral	0.075
NPC1	O15118-1.2	F21G	Neutral	0.127
NPC1	O15118-1.2	F21H	Neutral	0.044
NPC1	O15118-1.2	F21I	Neutral	0.049
NPC1	O15118-1.2	F21K	Neutral	0.058
NPC1	O15118-1.2	F21L	Neutral	0.048
NPC1	O15118-1.2	F21M	Neutral	0.042
NPC1	O15118-1.2	F21N	Neutral	0.082
NPC1	O15118-1.2	F21P	Neutral	0.174
NPC1	O15118-1.2	F21Q	Neutral	0.083
NPC1	O15118-1.2	F21R	Neutral	0.062
NPC1	O15118-1.2	F21S	Neutral	0.077
NPC1	O15118-1.2	F21T	Neutral	0.076
NPC1	O15118-1.2	F21V	Neutral	0.067
NPC1	O15118-1.2	F21W	Neutral	0.033
NPC1	O15118-1.2	F21Y	Neutral	0.012
NPC1	O15118-1.2	S22A	Neutral	0.034
NPC1	O15118-1.2	S22C	Neutral	0.06
NPC1	O15118-1.2	S22D	Neutral	0.047
NPC1	O15118-1.2	S22E	Neutral	0.054
NPC1	O15118-1.2	S22F	Neutral	0.088
NPC1	O15118-1.2	S22G	Neutral	0.061
NPC1	O15118-1.2	S22H	Neutral	0.093
NPC1	O15118-1.2	S22I	Neutral	0.083
NPC1	O15118-1.2	S22K	Neutral	0.056
NPC1	O15118-1.2	S22L	Neutral	0.085
NPC1	O15118-1.2	S22M	Neutral	0.069
NPC1	O15118-1.2	S22N	Neutral	0.035
NPC1	O15118-1.2	S22P	Neutral	0.067
NPC1	O15118-1.2	S22Q	Neutral	0.064
NPC1	O15118-1.2	S22R	Neutral	0.086
NPC1	O15118-1.2	S22T	Neutral	0.038
NPC1	O15118-1.2	S22V	Neutral	0.089
NPC1	O15118-1.2	S22W	Neutral	0.126
NPC1	O15118-1.2	S22Y	Neutral	0.117
NPC1	O15118-1.2	Q23A	Neutral	0.422
NPC1	O15118-1.2	Q23C	Pathogenic	0.529
NPC1	O15118-1.2	Q23D	Neutral	0.299
NPC1	O15118-1.2	Q23E	Neutral	0.156
NPC1	O15118-1.2	Q23F	Neutral	0.452
NPC1	O15118-1.2	Q23G	Pathogenic	0.571
NPC1	O15118-1.2	Q23H	Neutral	0.288
NPC1	O15118-1.2	Q23I	Neutral	0.434
NPC1	O15118-1.2	Q23K	Neutral	0.21
NPC1	O15118-1.2	Q23L	Neutral	0.351
NPC1	O15118-1.2	Q23M	Neutral	0.226
NPC1	O15118-1.2	Q23N	Neutral	0.304
NPC1	O15118-1.2	Q23P	Neutral	0.356
NPC1	O15118-1.2	Q23R	Neutral	0.222
NPC1	O15118-1.2	Q23S	Neutral	0.349
NPC1	O15118-1.2	Q23T	Neutral	0.388
NPC1	O15118-1.2	Q23V	Neutral	0.386
NPC1	O15118-1.2	Q23W	Neutral	0.363
NPC1	O15118-1.2	Q23Y	Neutral	0.342
NPC1	O15118-1.2	S24A	Neutral	0.089
NPC1	O15118-1.2	S24C	Neutral	0.15
NPC1	O15118-1.2	S24D	Neutral	0.119
NPC1	O15118-1.2	S24E	Neutral	0.136
NPC1	O15118-1.2	S24F	Neutral	0.21
NPC1	O15118-1.2	S24G	Neutral	0.151
NPC1	O15118-1.2	S24H	Neutral	0.221
NPC1	O15118-1.2	S24I	Neutral	0.199
NPC1	O15118-1.2	S24K	Neutral	0.141
NPC1	O15118-1.2	S24L	Neutral	0.204
NPC1	O15118-1.2	S24M	Neutral	0.169
NPC1	O15118-1.2	S24N	Neutral	0.091
NPC1	O15118-1.2	S24P	Neutral	0.164
NPC1	O15118-1.2	S24Q	Neutral	0.158
NPC1	O15118-1.2	S24R	Neutral	0.207
NPC1	O15118-1.2	S24T	Neutral	0.098
NPC1	O15118-1.2	S24V	Neutral	0.212
NPC1	O15118-1.2	S24W	Neutral	0.285
NPC1	O15118-1.2	S24Y	Neutral	0.267
NPC1	O15118-1.2	C25A	Pathogenic	0.726
NPC1	O15118-1.2	C25D	Pathogenic	0.844
NPC1	O15118-1.2	C25E	Pathogenic	0.903
NPC1	O15118-1.2	C25F	Pathogenic	0.868
NPC1	O15118-1.2	C25G	Pathogenic	0.895
NPC1	O15118-1.2	C25H	Pathogenic	0.896
NPC1	O15118-1.2	C25I	Pathogenic	0.807
NPC1	O15118-1.2	C25K	Pathogenic	0.868
NPC1	O15118-1.2	C25L	Pathogenic	0.812
NPC1	O15118-1.2	C25M	Pathogenic	0.835
NPC1	O15118-1.2	C25N	Pathogenic	0.855
NPC1	O15118-1.2	C25P	Pathogenic	0.898
NPC1	O15118-1.2	C25Q	Pathogenic	0.882
NPC1	O15118-1.2	C25R	Pathogenic	0.876
NPC1	O15118-1.2	C25S	Pathogenic	0.771
NPC1	O15118-1.2	C25T	Pathogenic	0.781
NPC1	O15118-1.2	C25V	Pathogenic	0.819
NPC1	O15118-1.2	C25W	Pathogenic	0.87
NPC1	O15118-1.2	C25Y	Pathogenic	0.899
NPC1	O15118-1.2	V26A	Pathogenic	0.509
NPC1	O15118-1.2	V26C	Pathogenic	0.63
NPC1	O15118-1.2	V26D	Pathogenic	0.666
NPC1	O15118-1.2	V26E	Pathogenic	0.571
NPC1	O15118-1.2	V26F	Pathogenic	0.619
NPC1	O15118-1.2	V26G	Pathogenic	0.77
NPC1	O15118-1.2	V26H	Pathogenic	0.728
NPC1	O15118-1.2	V26I	Neutral	0.244
NPC1	O15118-1.2	V26K	Pathogenic	0.581
NPC1	O15118-1.2	V26L	Neutral	0.42
NPC1	O15118-1.2	V26M	Neutral	0.458
NPC1	O15118-1.2	V26N	Pathogenic	0.672
NPC1	O15118-1.2	V26P	Pathogenic	0.691
NPC1	O15118-1.2	V26Q	Pathogenic	0.612
NPC1	O15118-1.2	V26R	Pathogenic	0.687
NPC1	O15118-1.2	V26S	Pathogenic	0.658
NPC1	O15118-1.2	V26T	Neutral	0.465
NPC1	O15118-1.2	V26W	Pathogenic	0.781
NPC1	O15118-1.2	V26Y	Pathogenic	0.652
NPC1	O15118-1.2	W27A	Pathogenic	0.96
NPC1	O15118-1.2	W27C	Pathogenic	0.947
NPC1	O15118-1.2	W27D	Pathogenic	0.955
NPC1	O15118-1.2	W27E	Pathogenic	0.931
NPC1	O15118-1.2	W27F	Pathogenic	0.846
NPC1	O15118-1.2	W27G	Pathogenic	0.942
NPC1	O15118-1.2	W27H	Pathogenic	0.918
NPC1	O15118-1.2	W27I	Pathogenic	0.965
NPC1	O15118-1.2	W27K	Pathogenic	0.911
NPC1	O15118-1.2	W27L	Pathogenic	0.948
NPC1	O15118-1.2	W27M	Pathogenic	0.913
NPC1	O15118-1.2	W27N	Pathogenic	0.956
NPC1	O15118-1.2	W27P	Pathogenic	0.972
NPC1	O15118-1.2	W27Q	Pathogenic	0.91
NPC1	O15118-1.2	W27R	Pathogenic	0.904
NPC1	O15118-1.2	W27S	Pathogenic	0.953
NPC1	O15118-1.2	W27T	Pathogenic	0.931
NPC1	O15118-1.2	W27V	Pathogenic	0.962
NPC1	O15118-1.2	W27Y	Pathogenic	0.732
NPC1	O15118-1.2	Y28A	Pathogenic	0.956
NPC1	O15118-1.2	Y28C	Pathogenic	0.96
NPC1	O15118-1.2	Y28D	Pathogenic	0.951
NPC1	O15118-1.2	Y28E	Pathogenic	0.925
NPC1	O15118-1.2	Y28F	Pathogenic	0.666
NPC1	O15118-1.2	Y28G	Pathogenic	0.97
NPC1	O15118-1.2	Y28H	Pathogenic	0.764
NPC1	O15118-1.2	Y28I	Pathogenic	0.908
NPC1	O15118-1.2	Y28K	Pathogenic	0.904
NPC1	O15118-1.2	Y28L	Pathogenic	0.911
NPC1	O15118-1.2	Y28M	Pathogenic	0.923
NPC1	O15118-1.2	Y28N	Pathogenic	0.931
NPC1	O15118-1.2	Y28P	Pathogenic	0.97
NPC1	O15118-1.2	Y28Q	Pathogenic	0.904
NPC1	O15118-1.2	Y28R	Pathogenic	0.904
NPC1	O15118-1.2	Y28S	Pathogenic	0.95
NPC1	O15118-1.2	Y28T	Pathogenic	0.948
NPC1	O15118-1.2	Y28V	Pathogenic	0.931
NPC1	O15118-1.2	Y28W	Pathogenic	0.734
NPC1	O15118-1.2	G29A	Pathogenic	0.8
NPC1	O15118-1.2	G29C	Pathogenic	0.919
NPC1	O15118-1.2	G29D	Pathogenic	0.854
NPC1	O15118-1.2	G29E	Pathogenic	0.909
NPC1	O15118-1.2	G29F	Pathogenic	0.922
NPC1	O15118-1.2	G29H	Pathogenic	0.926
NPC1	O15118-1.2	G29I	Pathogenic	0.941
NPC1	O15118-1.2	G29K	Pathogenic	0.912
NPC1	O15118-1.2	G29L	Pathogenic	0.943
NPC1	O15118-1.2	G29M	Pathogenic	0.93
NPC1	O15118-1.2	G29N	Pathogenic	0.812
NPC1	O15118-1.2	G29P	Pathogenic	0.897
NPC1	O15118-1.2	G29Q	Pathogenic	0.922
NPC1	O15118-1.2	G29R	Pathogenic	0.918
NPC1	O15118-1.2	G29S	Pathogenic	0.819
NPC1	O15118-1.2	G29T	Pathogenic	0.912
NPC1	O15118-1.2	G29V	Pathogenic	0.922
NPC1	O15118-1.2	G29W	Pathogenic	0.89
NPC1	O15118-1.2	G29Y	Pathogenic	0.941
NPC1	O15118-1.2	E30A	Pathogenic	0.779
NPC1	O15118-1.2	E30C	Pathogenic	0.889
NPC1	O15118-1.2	E30D	Pathogenic	0.557
NPC1	O15118-1.2	E30F	Pathogenic	0.809
NPC1	O15118-1.2	E30G	Pathogenic	0.866
NPC1	O15118-1.2	E30H	Pathogenic	0.676
NPC1	O15118-1.2	E30I	Pathogenic	0.798
NPC1	O15118-1.2	E30K	Pathogenic	0.643
NPC1	O15118-1.2	E30L	Pathogenic	0.803
NPC1	O15118-1.2	E30M	Pathogenic	0.764
NPC1	O15118-1.2	E30N	Pathogenic	0.731
NPC1	O15118-1.2	E30P	Pathogenic	0.728
NPC1	O15118-1.2	E30Q	Pathogenic	0.514
NPC1	O15118-1.2	E30R	Pathogenic	0.741
NPC1	O15118-1.2	E30S	Pathogenic	0.722
NPC1	O15118-1.2	E30T	Pathogenic	0.754
NPC1	O15118-1.2	E30V	Pathogenic	0.753
NPC1	O15118-1.2	E30W	Pathogenic	0.812
NPC1	O15118-1.2	E30Y	Pathogenic	0.797
NPC1	O15118-1.2	C31A	Pathogenic	0.731
NPC1	O15118-1.2	C31D	Pathogenic	0.847
NPC1	O15118-1.2	C31E	Pathogenic	0.905
NPC1	O15118-1.2	C31F	Pathogenic	0.871
NPC1	O15118-1.2	C31G	Pathogenic	0.897
NPC1	O15118-1.2	C31H	Pathogenic	0.898
NPC1	O15118-1.2	C31I	Pathogenic	0.81
NPC1	O15118-1.2	C31K	Pathogenic	0.871
NPC1	O15118-1.2	C31L	Pathogenic	0.815
NPC1	O15118-1.2	C31M	Pathogenic	0.838
NPC1	O15118-1.2	C31N	Pathogenic	0.858
NPC1	O15118-1.2	C31P	Pathogenic	0.9
NPC1	O15118-1.2	C31Q	Pathogenic	0.884
NPC1	O15118-1.2	C31R	Pathogenic	0.879
NPC1	O15118-1.2	C31S	Pathogenic	0.774
NPC1	O15118-1.2	C31T	Pathogenic	0.785
NPC1	O15118-1.2	C31V	Pathogenic	0.822
NPC1	O15118-1.2	C31W	Pathogenic	0.873
NPC1	O15118-1.2	C31Y	Pathogenic	0.901
NPC1	O15118-1.2	G32A	Neutral	0.381
NPC1	O15118-1.2	G32C	Pathogenic	0.637
NPC1	O15118-1.2	G32D	Neutral	0.473
NPC1	O15118-1.2	G32E	Pathogenic	0.606
NPC1	O15118-1.2	G32F	Pathogenic	0.644
NPC1	O15118-1.2	G32H	Pathogenic	0.658
NPC1	O15118-1.2	G32I	Pathogenic	0.712
NPC1	O15118-1.2	G32K	Pathogenic	0.616
NPC1	O15118-1.2	G32L	Pathogenic	0.719
NPC1	O15118-1.2	G32M	Pathogenic	0.67
NPC1	O15118-1.2	G32N	Neutral	0.4
NPC1	O15118-1.2	G32P	Pathogenic	0.572
NPC1	O15118-1.2	G32Q	Pathogenic	0.646
NPC1	O15118-1.2	G32R	Pathogenic	0.633
NPC1	O15118-1.2	G32S	Neutral	0.411
NPC1	O15118-1.2	G32T	Pathogenic	0.613
NPC1	O15118-1.2	G32V	Pathogenic	0.646
NPC1	O15118-1.2	G32W	Pathogenic	0.555
NPC1	O15118-1.2	G32Y	Pathogenic	0.712
NPC1	O15118-1.2	I33A	Neutral	0.18
NPC1	O15118-1.2	I33C	Neutral	0.197
NPC1	O15118-1.2	I33D	Neutral	0.223
NPC1	O15118-1.2	I33E	Neutral	0.212
NPC1	O15118-1.2	I33F	Neutral	0.156
NPC1	O15118-1.2	I33G	Neutral	0.414
NPC1	O15118-1.2	I33H	Neutral	0.248
NPC1	O15118-1.2	I33K	Neutral	0.189
NPC1	O15118-1.2	I33L	Neutral	0.072
NPC1	O15118-1.2	I33M	Neutral	0.089
NPC1	O15118-1.2	I33N	Neutral	0.228
NPC1	O15118-1.2	I33P	Neutral	0.321
NPC1	O15118-1.2	I33Q	Neutral	0.231
NPC1	O15118-1.2	I33R	Neutral	0.201
NPC1	O15118-1.2	I33S	Neutral	0.217
NPC1	O15118-1.2	I33T	Neutral	0.156
NPC1	O15118-1.2	I33V	Neutral	0.048
NPC1	O15118-1.2	I33W	Neutral	0.376
NPC1	O15118-1.2	I33Y	Neutral	0.176
NPC1	O15118-1.2	A34C	Neutral	0.282
NPC1	O15118-1.2	A34D	Neutral	0.434
NPC1	O15118-1.2	A34E	Neutral	0.378
NPC1	O15118-1.2	A34F	Neutral	0.466
NPC1	O15118-1.2	A34G	Neutral	0.307
NPC1	O15118-1.2	A34H	Pathogenic	0.549
NPC1	O15118-1.2	A34I	Neutral	0.356
NPC1	O15118-1.2	A34K	Neutral	0.387
NPC1	O15118-1.2	A34L	Neutral	0.364
NPC1	O15118-1.2	A34M	Neutral	0.401
NPC1	O15118-1.2	A34N	Neutral	0.455
NPC1	O15118-1.2	A34P	Neutral	0.392
NPC1	O15118-1.2	A34Q	Neutral	0.418
NPC1	O15118-1.2	A34R	Neutral	0.405
NPC1	O15118-1.2	A34S	Neutral	0.216
NPC1	O15118-1.2	A34T	Neutral	0.335
NPC1	O15118-1.2	A34V	Neutral	0.289
NPC1	O15118-1.2	A34W	Pathogenic	0.566
NPC1	O15118-1.2	A34Y	Pathogenic	0.544
NPC1	O15118-1.2	Y35A	Neutral	0.212
NPC1	O15118-1.2	Y35C	Neutral	0.229
NPC1	O15118-1.2	Y35D	Neutral	0.193
NPC1	O15118-1.2	Y35E	Neutral	0.133
NPC1	O15118-1.2	Y35F	Neutral	0.024
NPC1	O15118-1.2	Y35G	Neutral	0.287
NPC1	O15118-1.2	Y35H	Neutral	0.038
NPC1	O15118-1.2	Y35I	Neutral	0.109
NPC1	O15118-1.2	Y35K	Neutral	0.104
NPC1	O15118-1.2	Y35L	Neutral	0.112
NPC1	O15118-1.2	Y35M	Neutral	0.129
NPC1	O15118-1.2	Y35N	Neutral	0.143
NPC1	O15118-1.2	Y35P	Neutral	0.284
NPC1	O15118-1.2	Y35Q	Neutral	0.104
NPC1	O15118-1.2	Y35R	Neutral	0.104
NPC1	O15118-1.2	Y35S	Neutral	0.188
NPC1	O15118-1.2	Y35T	Neutral	0.185
NPC1	O15118-1.2	Y35V	Neutral	0.143
NPC1	O15118-1.2	Y35W	Neutral	0.033
NPC1	O15118-1.2	G36A	Neutral	0.272
NPC1	O15118-1.2	G36C	Pathogenic	0.515
NPC1	O15118-1.2	G36D	Neutral	0.352
NPC1	O15118-1.2	G36E	Neutral	0.482
NPC1	O15118-1.2	G36F	Pathogenic	0.523
NPC1	O15118-1.2	G36H	Pathogenic	0.538
NPC1	O15118-1.2	G36I	Pathogenic	0.6
NPC1	O15118-1.2	G36K	Neutral	0.492
NPC1	O15118-1.2	G36L	Pathogenic	0.608
NPC1	O15118-1.2	G36M	Pathogenic	0.552
NPC1	O15118-1.2	G36N	Neutral	0.287
NPC1	O15118-1.2	G36P	Neutral	0.447
NPC1	O15118-1.2	G36Q	Pathogenic	0.525
NPC1	O15118-1.2	G36R	Pathogenic	0.511
NPC1	O15118-1.2	G36S	Neutral	0.297
NPC1	O15118-1.2	G36T	Neutral	0.49
NPC1	O15118-1.2	G36V	Pathogenic	0.525
NPC1	O15118-1.2	G36W	Neutral	0.431
NPC1	O15118-1.2	G36Y	Pathogenic	0.599
NPC1	O15118-1.2	D37A	Neutral	0.337
NPC1	O15118-1.2	D37C	Neutral	0.348
NPC1	O15118-1.2	D37E	Neutral	0.126
NPC1	O15118-1.2	D37F	Neutral	0.34
NPC1	O15118-1.2	D37G	Neutral	0.301
NPC1	O15118-1.2	D37H	Neutral	0.272
NPC1	O15118-1.2	D37I	Neutral	0.325
NPC1	O15118-1.2	D37K	Neutral	0.342
NPC1	O15118-1.2	D37L	Neutral	0.422
NPC1	O15118-1.2	D37M	Neutral	0.368
NPC1	O15118-1.2	D37N	Neutral	0.162
NPC1	O15118-1.2	D37P	Neutral	0.208
NPC1	O15118-1.2	D37Q	Neutral	0.218
NPC1	O15118-1.2	D37R	Neutral	0.451
NPC1	O15118-1.2	D37S	Neutral	0.203
NPC1	O15118-1.2	D37T	Neutral	0.235
NPC1	O15118-1.2	D37V	Neutral	0.342
NPC1	O15118-1.2	D37W	Neutral	0.435
NPC1	O15118-1.2	D37Y	Neutral	0.413
NPC1	O15118-1.2	K38A	Pathogenic	0.619
NPC1	O15118-1.2	K38C	Pathogenic	0.715
NPC1	O15118-1.2	K38D	Pathogenic	0.668
NPC1	O15118-1.2	K38E	Neutral	0.444
NPC1	O15118-1.2	K38F	Pathogenic	0.588
NPC1	O15118-1.2	K38G	Pathogenic	0.748
NPC1	O15118-1.2	K38H	Pathogenic	0.559
NPC1	O15118-1.2	K38I	Pathogenic	0.603
NPC1	O15118-1.2	K38L	Pathogenic	0.516
NPC1	O15118-1.2	K38M	Neutral	0.459
NPC1	O15118-1.2	K38N	Pathogenic	0.557
NPC1	O15118-1.2	K38P	Pathogenic	0.553
NPC1	O15118-1.2	K38Q	Neutral	0.403
NPC1	O15118-1.2	K38R	Neutral	0.36
NPC1	O15118-1.2	K38S	Pathogenic	0.545
NPC1	O15118-1.2	K38T	Pathogenic	0.586
NPC1	O15118-1.2	K38V	Pathogenic	0.584
NPC1	O15118-1.2	K38W	Pathogenic	0.592
NPC1	O15118-1.2	K38Y	Pathogenic	0.57
NPC1	O15118-1.2	R39A	Neutral	0.326
NPC1	O15118-1.2	R39C	Neutral	0.428
NPC1	O15118-1.2	R39D	Neutral	0.469
NPC1	O15118-1.2	R39E	Neutral	0.259
NPC1	O15118-1.2	R39F	Neutral	0.298
NPC1	O15118-1.2	R39G	Neutral	0.47
NPC1	O15118-1.2	R39H	Neutral	0.204
NPC1	O15118-1.2	R39I	Neutral	0.311
NPC1	O15118-1.2	R39K	Neutral	0.135
NPC1	O15118-1.2	R39L	Neutral	0.241
NPC1	O15118-1.2	R39M	Neutral	0.202
NPC1	O15118-1.2	R39N	Neutral	0.272
NPC1	O15118-1.2	R39P	Neutral	0.351
NPC1	O15118-1.2	R39Q	Neutral	0.167
NPC1	O15118-1.2	R39S	Neutral	0.344
NPC1	O15118-1.2	R39T	Neutral	0.296
NPC1	O15118-1.2	R39V	Neutral	0.381
NPC1	O15118-1.2	R39W	Neutral	0.269
NPC1	O15118-1.2	R39Y	Neutral	0.268
NPC1	O15118-1.2	Y40A	Pathogenic	0.678
NPC1	O15118-1.2	Y40C	Pathogenic	0.698
NPC1	O15118-1.2	Y40D	Pathogenic	0.651
NPC1	O15118-1.2	Y40E	Pathogenic	0.543
NPC1	O15118-1.2	Y40F	Neutral	0.16
NPC1	O15118-1.2	Y40G	Pathogenic	0.758
NPC1	O15118-1.2	Y40H	Neutral	0.237
NPC1	O15118-1.2	Y40I	Neutral	0.487
NPC1	O15118-1.2	Y40K	Neutral	0.475
NPC1	O15118-1.2	Y40L	Neutral	0.496
NPC1	O15118-1.2	Y40M	Pathogenic	0.535
NPC1	O15118-1.2	Y40N	Pathogenic	0.566
NPC1	O15118-1.2	Y40P	Pathogenic	0.755
NPC1	O15118-1.2	Y40Q	Neutral	0.474
NPC1	O15118-1.2	Y40R	Neutral	0.475
NPC1	O15118-1.2	Y40S	Pathogenic	0.644
NPC1	O15118-1.2	Y40T	Pathogenic	0.638
NPC1	O15118-1.2	Y40V	Pathogenic	0.564
NPC1	O15118-1.2	Y40W	Neutral	0.21
NPC1	O15118-1.2	N41A	Pathogenic	0.672
NPC1	O15118-1.2	N41C	Pathogenic	0.682
NPC1	O15118-1.2	N41D	Neutral	0.416
NPC1	O15118-1.2	N41E	Pathogenic	0.535
NPC1	O15118-1.2	N41F	Pathogenic	0.662
NPC1	O15118-1.2	N41G	Pathogenic	0.541
NPC1	O15118-1.2	N41H	Neutral	0.396
NPC1	O15118-1.2	N41I	Pathogenic	0.646
NPC1	O15118-1.2	N41K	Pathogenic	0.545
NPC1	O15118-1.2	N41L	Pathogenic	0.654
NPC1	O15118-1.2	N41M	Pathogenic	0.6
NPC1	O15118-1.2	N41P	Pathogenic	0.609
NPC1	O15118-1.2	N41Q	Pathogenic	0.514
NPC1	O15118-1.2	N41R	Pathogenic	0.563
NPC1	O15118-1.2	N41S	Neutral	0.411
NPC1	O15118-1.2	N41T	Neutral	0.452
NPC1	O15118-1.2	N41V	Pathogenic	0.664
NPC1	O15118-1.2	N41W	Pathogenic	0.745
NPC1	O15118-1.2	N41Y	Pathogenic	0.645
NPC1	O15118-1.2	C42A	Pathogenic	0.694
NPC1	O15118-1.2	C42D	Pathogenic	0.823
NPC1	O15118-1.2	C42E	Pathogenic	0.888
NPC1	O15118-1.2	C42F	Pathogenic	0.849
NPC1	O15118-1.2	C42G	Pathogenic	0.88
NPC1	O15118-1.2	C42H	Pathogenic	0.88
NPC1	O15118-1.2	C42I	Pathogenic	0.781
NPC1	O15118-1.2	C42K	Pathogenic	0.849
NPC1	O15118-1.2	C42L	Pathogenic	0.787
NPC1	O15118-1.2	C42M	Pathogenic	0.812
NPC1	O15118-1.2	C42N	Pathogenic	0.835
NPC1	O15118-1.2	C42P	Pathogenic	0.883
NPC1	O15118-1.2	C42Q	Pathogenic	0.865
NPC1	O15118-1.2	C42R	Pathogenic	0.858
NPC1	O15118-1.2	C42S	Pathogenic	0.742
NPC1	O15118-1.2	C42T	Pathogenic	0.753
NPC1	O15118-1.2	C42V	Pathogenic	0.794
NPC1	O15118-1.2	C42W	Pathogenic	0.851
NPC1	O15118-1.2	C42Y	Pathogenic	0.883
NPC1	O15118-1.2	E43A	Neutral	0.121
NPC1	O15118-1.2	E43C	Neutral	0.238
NPC1	O15118-1.2	E43D	Neutral	0.047
NPC1	O15118-1.2	E43F	Neutral	0.142
NPC1	O15118-1.2	E43G	Neutral	0.201
NPC1	O15118-1.2	E43H	Neutral	0.075
NPC1	O15118-1.2	E43I	Neutral	0.133
NPC1	O15118-1.2	E43K	Neutral	0.066
NPC1	O15118-1.2	E43L	Neutral	0.137
NPC1	O15118-1.2	E43M	Neutral	0.112
NPC1	O15118-1.2	E43N	Neutral	0.096
NPC1	O15118-1.2	E43P	Neutral	0.095
NPC1	O15118-1.2	E43Q	Neutral	0.04
NPC1	O15118-1.2	E43R	Neutral	0.1
NPC1	O15118-1.2	E43S	Neutral	0.092
NPC1	O15118-1.2	E43T	Neutral	0.107
NPC1	O15118-1.2	E43V	Neutral	0.106
NPC1	O15118-1.2	E43W	Neutral	0.144
NPC1	O15118-1.2	E43Y	Neutral	0.133
NPC1	O15118-1.2	Y44A	Pathogenic	0.946
NPC1	O15118-1.2	Y44C	Pathogenic	0.951
NPC1	O15118-1.2	Y44D	Pathogenic	0.94
NPC1	O15118-1.2	Y44E	Pathogenic	0.909
NPC1	O15118-1.2	Y44F	Pathogenic	0.615
NPC1	O15118-1.2	Y44G	Pathogenic	0.963
NPC1	O15118-1.2	Y44H	Pathogenic	0.722
NPC1	O15118-1.2	Y44I	Pathogenic	0.888
NPC1	O15118-1.2	Y44K	Pathogenic	0.883
NPC1	O15118-1.2	Y44L	Pathogenic	0.891
NPC1	O15118-1.2	Y44M	Pathogenic	0.906
NPC1	O15118-1.2	Y44N	Pathogenic	0.916
NPC1	O15118-1.2	Y44P	Pathogenic	0.963
NPC1	O15118-1.2	Y44Q	Pathogenic	0.883
NPC1	O15118-1.2	Y44R	Pathogenic	0.883
NPC1	O15118-1.2	Y44S	Pathogenic	0.938
NPC1	O15118-1.2	Y44T	Pathogenic	0.937
NPC1	O15118-1.2	Y44V	Pathogenic	0.915
NPC1	O15118-1.2	Y44W	Pathogenic	0.689
NPC1	O15118-1.2	S45A	Neutral	0.146
NPC1	O15118-1.2	S45C	Neutral	0.236
NPC1	O15118-1.2	S45D	Neutral	0.192
NPC1	O15118-1.2	S45E	Neutral	0.217
NPC1	O15118-1.2	S45F	Neutral	0.318
NPC1	O15118-1.2	S45G	Neutral	0.238
NPC1	O15118-1.2	S45H	Neutral	0.332
NPC1	O15118-1.2	S45I	Neutral	0.303
NPC1	O15118-1.2	S45K	Neutral	0.224
NPC1	O15118-1.2	S45L	Neutral	0.31
NPC1	O15118-1.2	S45M	Neutral	0.263
NPC1	O15118-1.2	S45N	Neutral	0.15
NPC1	O15118-1.2	S45P	Neutral	0.257
NPC1	O15118-1.2	S45Q	Neutral	0.247
NPC1	O15118-1.2	S45R	Neutral	0.313
NPC1	O15118-1.2	S45T	Neutral	0.159
NPC1	O15118-1.2	S45V	Neutral	0.32
NPC1	O15118-1.2	S45W	Neutral	0.411
NPC1	O15118-1.2	S45Y	Neutral	0.389
NPC1	O15118-1.2	G46A	Pathogenic	0.792
NPC1	O15118-1.2	G46C	Pathogenic	0.916
NPC1	O15118-1.2	G46D	Pathogenic	0.848
NPC1	O15118-1.2	G46E	Pathogenic	0.905
NPC1	O15118-1.2	G46F	Pathogenic	0.918
NPC1	O15118-1.2	G46H	Pathogenic	0.923
NPC1	O15118-1.2	G46I	Pathogenic	0.939
NPC1	O15118-1.2	G46K	Pathogenic	0.908
NPC1	O15118-1.2	G46L	Pathogenic	0.941
NPC1	O15118-1.2	G46M	Pathogenic	0.926
NPC1	O15118-1.2	G46N	Pathogenic	0.805
NPC1	O15118-1.2	G46P	Pathogenic	0.892
NPC1	O15118-1.2	G46Q	Pathogenic	0.919
NPC1	O15118-1.2	G46R	Pathogenic	0.914
NPC1	O15118-1.2	G46S	Pathogenic	0.812
NPC1	O15118-1.2	G46T	Pathogenic	0.908
NPC1	O15118-1.2	G46V	Pathogenic	0.919
NPC1	O15118-1.2	G46W	Pathogenic	0.885
NPC1	O15118-1.2	G46Y	Pathogenic	0.939
NPC1	O15118-1.2	P47A	Pathogenic	0.673
NPC1	O15118-1.2	P47C	Pathogenic	0.806
NPC1	O15118-1.2	P47D	Pathogenic	0.557
NPC1	O15118-1.2	P47E	Pathogenic	0.595
NPC1	O15118-1.2	P47F	Pathogenic	0.857
NPC1	O15118-1.2	P47G	Pathogenic	0.754
NPC1	O15118-1.2	P47H	Pathogenic	0.746
NPC1	O15118-1.2	P47I	Pathogenic	0.792
NPC1	O15118-1.2	P47K	Pathogenic	0.604
NPC1	O15118-1.2	P47L	Pathogenic	0.797
NPC1	O15118-1.2	P47M	Pathogenic	0.758
NPC1	O15118-1.2	P47N	Pathogenic	0.669
NPC1	O15118-1.2	P47Q	Pathogenic	0.635
NPC1	O15118-1.2	P47R	Pathogenic	0.708
NPC1	O15118-1.2	P47S	Pathogenic	0.639
NPC1	O15118-1.2	P47T	Pathogenic	0.642
NPC1	O15118-1.2	P47V	Pathogenic	0.737
NPC1	O15118-1.2	P47W	Pathogenic	0.859
NPC1	O15118-1.2	P47Y	Pathogenic	0.848
NPC1	O15118-1.2	P48A	Pathogenic	0.795
NPC1	O15118-1.2	P48C	Pathogenic	0.887
NPC1	O15118-1.2	P48D	Pathogenic	0.704
NPC1	O15118-1.2	P48E	Pathogenic	0.734
NPC1	O15118-1.2	P48F	Pathogenic	0.919
NPC1	O15118-1.2	P48G	Pathogenic	0.852
NPC1	O15118-1.2	P48H	Pathogenic	0.847
NPC1	O15118-1.2	P48I	Pathogenic	0.878
NPC1	O15118-1.2	P48K	Pathogenic	0.742
NPC1	O15118-1.2	P48L	Pathogenic	0.881
NPC1	O15118-1.2	P48M	Pathogenic	0.855
NPC1	O15118-1.2	P48N	Pathogenic	0.792
NPC1	O15118-1.2	P48Q	Pathogenic	0.766
NPC1	O15118-1.2	P48R	Pathogenic	0.82
NPC1	O15118-1.2	P48S	Pathogenic	0.769
NPC1	O15118-1.2	P48T	Pathogenic	0.772
NPC1	O15118-1.2	P48V	Pathogenic	0.841
NPC1	O15118-1.2	P48W	Pathogenic	0.92
NPC1	O15118-1.2	P48Y	Pathogenic	0.913
NPC1	O15118-1.2	K49A	Pathogenic	0.634
NPC1	O15118-1.2	K49C	Pathogenic	0.727
NPC1	O15118-1.2	K49D	Pathogenic	0.682
NPC1	O15118-1.2	K49E	Neutral	0.459
NPC1	O15118-1.2	K49F	Pathogenic	0.603
NPC1	O15118-1.2	K49G	Pathogenic	0.76
NPC1	O15118-1.2	K49H	Pathogenic	0.574
NPC1	O15118-1.2	K49I	Pathogenic	0.617
NPC1	O15118-1.2	K49L	Pathogenic	0.532
NPC1	O15118-1.2	K49M	Neutral	0.474
NPC1	O15118-1.2	K49N	Pathogenic	0.572
NPC1	O15118-1.2	K49P	Pathogenic	0.568
NPC1	O15118-1.2	K49Q	Neutral	0.418
NPC1	O15118-1.2	K49R	Neutral	0.374
NPC1	O15118-1.2	K49S	Pathogenic	0.56
NPC1	O15118-1.2	K49T	Pathogenic	0.601
NPC1	O15118-1.2	K49V	Pathogenic	0.599
NPC1	O15118-1.2	K49W	Pathogenic	0.607
NPC1	O15118-1.2	K49Y	Pathogenic	0.585
NPC1	O15118-1.2	P50A	Pathogenic	0.516
NPC1	O15118-1.2	P50C	Pathogenic	0.683
NPC1	O15118-1.2	P50D	Neutral	0.395
NPC1	O15118-1.2	P50E	Neutral	0.432
NPC1	O15118-1.2	P50F	Pathogenic	0.757
NPC1	O15118-1.2	P50G	Pathogenic	0.613
NPC1	O15118-1.2	P50H	Pathogenic	0.604
NPC1	O15118-1.2	P50I	Pathogenic	0.663
NPC1	O15118-1.2	P50K	Neutral	0.441
NPC1	O15118-1.2	P50L	Pathogenic	0.671
NPC1	O15118-1.2	P50M	Pathogenic	0.618
NPC1	O15118-1.2	P50N	Pathogenic	0.511
NPC1	O15118-1.2	P50Q	Neutral	0.473
NPC1	O15118-1.2	P50R	Pathogenic	0.556
NPC1	O15118-1.2	P50S	Neutral	0.478
NPC1	O15118-1.2	P50T	Neutral	0.481
NPC1	O15118-1.2	P50V	Pathogenic	0.592
NPC1	O15118-1.2	P50W	Pathogenic	0.76
NPC1	O15118-1.2	P50Y	Pathogenic	0.743
NPC1	O15118-1.2	L51A	Pathogenic	0.772
NPC1	O15118-1.2	L51C	Pathogenic	0.791
NPC1	O15118-1.2	L51D	Pathogenic	0.867
NPC1	O15118-1.2	L51E	Pathogenic	0.806
NPC1	O15118-1.2	L51F	Pathogenic	0.729
NPC1	O15118-1.2	L51G	Pathogenic	0.916
NPC1	O15118-1.2	L51H	Pathogenic	0.835
NPC1	O15118-1.2	L51I	Pathogenic	0.536
NPC1	O15118-1.2	L51K	Pathogenic	0.71
NPC1	O15118-1.2	L51M	Pathogenic	0.506
NPC1	O15118-1.2	L51N	Pathogenic	0.82
NPC1	O15118-1.2	L51P	Pathogenic	0.88
NPC1	O15118-1.2	L51Q	Pathogenic	0.759
NPC1	O15118-1.2	L51R	Pathogenic	0.725
NPC1	O15118-1.2	L51S	Pathogenic	0.811
NPC1	O15118-1.2	L51T	Pathogenic	0.74
NPC1	O15118-1.2	L51V	Pathogenic	0.627
NPC1	O15118-1.2	L51W	Pathogenic	0.855
NPC1	O15118-1.2	L51Y	Pathogenic	0.768
NPC1	O15118-1.2	P52A	Neutral	0.422
NPC1	O15118-1.2	P52C	Pathogenic	0.597
NPC1	O15118-1.2	P52D	Neutral	0.309
NPC1	O15118-1.2	P52E	Neutral	0.343
NPC1	O15118-1.2	P52F	Pathogenic	0.681
NPC1	O15118-1.2	P52G	Pathogenic	0.521
NPC1	O15118-1.2	P52H	Pathogenic	0.511
NPC1	O15118-1.2	P52I	Pathogenic	0.575
NPC1	O15118-1.2	P52K	Neutral	0.352
NPC1	O15118-1.2	P52L	Pathogenic	0.583
NPC1	O15118-1.2	P52M	Pathogenic	0.526
NPC1	O15118-1.2	P52N	Neutral	0.418
NPC1	O15118-1.2	P52Q	Neutral	0.382
NPC1	O15118-1.2	P52R	Neutral	0.462
NPC1	O15118-1.2	P52S	Neutral	0.386
NPC1	O15118-1.2	P52T	Neutral	0.389
NPC1	O15118-1.2	P52V	Neutral	0.499
NPC1	O15118-1.2	P52W	Pathogenic	0.684
NPC1	O15118-1.2	P52Y	Pathogenic	0.665
NPC1	O15118-1.2	K53A	Neutral	0.2
NPC1	O15118-1.2	K53C	Neutral	0.278
NPC1	O15118-1.2	K53D	Neutral	0.236
NPC1	O15118-1.2	K53E	Neutral	0.109
NPC1	O15118-1.2	K53F	Neutral	0.179
NPC1	O15118-1.2	K53G	Neutral	0.313
NPC1	O15118-1.2	K53H	Neutral	0.163
NPC1	O15118-1.2	K53I	Neutral	0.189
NPC1	O15118-1.2	K53L	Neutral	0.141
NPC1	O15118-1.2	K53M	Neutral	0.115
NPC1	O15118-1.2	K53N	Neutral	0.161
NPC1	O15118-1.2	K53P	Neutral	0.159
NPC1	O15118-1.2	K53Q	Neutral	0.094
NPC1	O15118-1.2	K53R	Neutral	0.079
NPC1	O15118-1.2	K53S	Neutral	0.155
NPC1	O15118-1.2	K53T	Neutral	0.178
NPC1	O15118-1.2	K53V	Neutral	0.177
NPC1	O15118-1.2	K53W	Neutral	0.182
NPC1	O15118-1.2	K53Y	Neutral	0.169
NPC1	O15118-1.2	D54A	Pathogenic	0.52
NPC1	O15118-1.2	D54C	Pathogenic	0.532
NPC1	O15118-1.2	D54E	Neutral	0.234
NPC1	O15118-1.2	D54F	Pathogenic	0.524
NPC1	O15118-1.2	D54G	Neutral	0.478
NPC1	O15118-1.2	D54H	Neutral	0.443
NPC1	O15118-1.2	D54I	Pathogenic	0.506
NPC1	O15118-1.2	D54K	Pathogenic	0.525
NPC1	O15118-1.2	D54L	Pathogenic	0.609
NPC1	O15118-1.2	D54M	Pathogenic	0.553
NPC1	O15118-1.2	D54N	Neutral	0.291
NPC1	O15118-1.2	D54P	Neutral	0.359
NPC1	O15118-1.2	D54Q	Neutral	0.373
NPC1	O15118-1.2	D54R	Pathogenic	0.637
NPC1	O15118-1.2	D54S	Neutral	0.352
NPC1	O15118-1.2	D54T	Neutral	0.396
NPC1	O15118-1.2	D54V	Pathogenic	0.526
NPC1	O15118-1.2	D54W	Pathogenic	0.622
NPC1	O15118-1.2	D54Y	Pathogenic	0.6
NPC1	O15118-1.2	G55A	Pathogenic	0.76
NPC1	O15118-1.2	G55C	Pathogenic	0.9
NPC1	O15118-1.2	G55D	Pathogenic	0.822
NPC1	O15118-1.2	G55E	Pathogenic	0.888
NPC1	O15118-1.2	G55F	Pathogenic	0.903
NPC1	O15118-1.2	G55H	Pathogenic	0.908
NPC1	O15118-1.2	G55I	Pathogenic	0.927
NPC1	O15118-1.2	G55K	Pathogenic	0.892
NPC1	O15118-1.2	G55L	Pathogenic	0.929
NPC1	O15118-1.2	G55M	Pathogenic	0.913
NPC1	O15118-1.2	G55N	Pathogenic	0.774
NPC1	O15118-1.2	G55P	Pathogenic	0.873
NPC1	O15118-1.2	G55Q	Pathogenic	0.904
NPC1	O15118-1.2	G55R	Pathogenic	0.899
NPC1	O15118-1.2	G55S	Pathogenic	0.782
NPC1	O15118-1.2	G55T	Pathogenic	0.891
NPC1	O15118-1.2	G55V	Pathogenic	0.904
NPC1	O15118-1.2	G55W	Pathogenic	0.865
NPC1	O15118-1.2	G55Y	Pathogenic	0.927
NPC1	O15118-1.2	Y56A	Pathogenic	0.571
NPC1	O15118-1.2	Y56C	Pathogenic	0.594
NPC1	O15118-1.2	Y56D	Pathogenic	0.542
NPC1	O15118-1.2	Y56E	Neutral	0.43
NPC1	O15118-1.2	Y56F	Neutral	0.108
NPC1	O15118-1.2	Y56G	Pathogenic	0.665
NPC1	O15118-1.2	Y56H	Neutral	0.165
NPC1	O15118-1.2	Y56I	Neutral	0.375
NPC1	O15118-1.2	Y56K	Neutral	0.364
NPC1	O15118-1.2	Y56L	Neutral	0.383
NPC1	O15118-1.2	Y56M	Neutral	0.421
NPC1	O15118-1.2	Y56N	Neutral	0.452
NPC1	O15118-1.2	Y56P	Pathogenic	0.661
NPC1	O15118-1.2	Y56Q	Neutral	0.363
NPC1	O15118-1.2	Y56R	Neutral	0.364
NPC1	O15118-1.2	Y56S	Pathogenic	0.534
NPC1	O15118-1.2	Y56T	Pathogenic	0.528
NPC1	O15118-1.2	Y56V	Neutral	0.45
NPC1	O15118-1.2	Y56W	Neutral	0.144
NPC1	O15118-1.2	D57A	Neutral	0.452
NPC1	O15118-1.2	D57C	Neutral	0.463
NPC1	O15118-1.2	D57E	Neutral	0.189
NPC1	O15118-1.2	D57F	Neutral	0.455
NPC1	O15118-1.2	D57G	Neutral	0.41
NPC1	O15118-1.2	D57H	Neutral	0.377
NPC1	O15118-1.2	D57I	Neutral	0.438
NPC1	O15118-1.2	D57K	Neutral	0.457
NPC1	O15118-1.2	D57L	Pathogenic	0.542
NPC1	O15118-1.2	D57M	Neutral	0.485
NPC1	O15118-1.2	D57N	Neutral	0.238
NPC1	O15118-1.2	D57P	Neutral	0.298
NPC1	O15118-1.2	D57Q	Neutral	0.311
NPC1	O15118-1.2	D57R	Pathogenic	0.571
NPC1	O15118-1.2	D57S	Neutral	0.292
NPC1	O15118-1.2	D57T	Neutral	0.333
NPC1	O15118-1.2	D57V	Neutral	0.457
NPC1	O15118-1.2	D57W	Pathogenic	0.555
NPC1	O15118-1.2	D57Y	Pathogenic	0.533
NPC1	O15118-1.2	L58A	Neutral	0.496
NPC1	O15118-1.2	L58C	Pathogenic	0.523
NPC1	O15118-1.2	L58D	Pathogenic	0.654
NPC1	O15118-1.2	L58E	Pathogenic	0.547
NPC1	O15118-1.2	L58F	Neutral	0.439
NPC1	O15118-1.2	L58G	Pathogenic	0.76
NPC1	O15118-1.2	L58H	Pathogenic	0.596
NPC1	O15118-1.2	L58I	Neutral	0.252
NPC1	O15118-1.2	L58K	Neutral	0.416
NPC1	O15118-1.2	L58M	Neutral	0.23
NPC1	O15118-1.2	L58N	Pathogenic	0.569
NPC1	O15118-1.2	L58P	Pathogenic	0.68
NPC1	O15118-1.2	L58Q	Neutral	0.478
NPC1	O15118-1.2	L58R	Neutral	0.434
NPC1	O15118-1.2	L58S	Pathogenic	0.555
NPC1	O15118-1.2	L58T	Neutral	0.453
NPC1	O15118-1.2	L58V	Neutral	0.328
NPC1	O15118-1.2	L58W	Pathogenic	0.632
NPC1	O15118-1.2	L58Y	Neutral	0.49
NPC1	O15118-1.2	V59A	Neutral	0.435
NPC1	O15118-1.2	V59C	Pathogenic	0.558
NPC1	O15118-1.2	V59D	Pathogenic	0.597
NPC1	O15118-1.2	V59E	Neutral	0.497
NPC1	O15118-1.2	V59F	Pathogenic	0.547
NPC1	O15118-1.2	V59G	Pathogenic	0.713
NPC1	O15118-1.2	V59H	Pathogenic	0.665
NPC1	O15118-1.2	V59I	Neutral	0.194
NPC1	O15118-1.2	V59K	Pathogenic	0.508
NPC1	O15118-1.2	V59L	Neutral	0.349
NPC1	O15118-1.2	V59M	Neutral	0.386
NPC1	O15118-1.2	V59N	Pathogenic	0.603
NPC1	O15118-1.2	V59P	Pathogenic	0.624
NPC1	O15118-1.2	V59Q	Pathogenic	0.54
NPC1	O15118-1.2	V59R	Pathogenic	0.62
NPC1	O15118-1.2	V59S	Pathogenic	0.589
NPC1	O15118-1.2	V59T	Neutral	0.393
NPC1	O15118-1.2	V59W	Pathogenic	0.726
NPC1	O15118-1.2	V59Y	Pathogenic	0.581
NPC1	O15118-1.2	Q60A	Neutral	0.41
NPC1	O15118-1.2	Q60C	Pathogenic	0.517
NPC1	O15118-1.2	Q60D	Neutral	0.289
NPC1	O15118-1.2	Q60E	Neutral	0.149
NPC1	O15118-1.2	Q60F	Neutral	0.44
NPC1	O15118-1.2	Q60G	Pathogenic	0.559
NPC1	O15118-1.2	Q60H	Neutral	0.279
NPC1	O15118-1.2	Q60I	Neutral	0.422
NPC1	O15118-1.2	Q60K	Neutral	0.202
NPC1	O15118-1.2	Q60L	Neutral	0.34
NPC1	O15118-1.2	Q60M	Neutral	0.217
NPC1	O15118-1.2	Q60N	Neutral	0.294
NPC1	O15118-1.2	Q60P	Neutral	0.345
NPC1	O15118-1.2	Q60R	Neutral	0.214
NPC1	O15118-1.2	Q60S	Neutral	0.338
NPC1	O15118-1.2	Q60T	Neutral	0.376
NPC1	O15118-1.2	Q60V	Neutral	0.375
NPC1	O15118-1.2	Q60W	Neutral	0.352
NPC1	O15118-1.2	Q60Y	Neutral	0.331
NPC1	O15118-1.2	E61A	Pathogenic	0.561
NPC1	O15118-1.2	E61C	Pathogenic	0.743
NPC1	O15118-1.2	E61D	Neutral	0.313
NPC1	O15118-1.2	E61F	Pathogenic	0.605
NPC1	O15118-1.2	E61G	Pathogenic	0.7
NPC1	O15118-1.2	E61H	Neutral	0.43
NPC1	O15118-1.2	E61I	Pathogenic	0.588
NPC1	O15118-1.2	E61K	Neutral	0.395
NPC1	O15118-1.2	E61L	Pathogenic	0.597
NPC1	O15118-1.2	E61M	Pathogenic	0.54
NPC1	O15118-1.2	E61N	Neutral	0.497
NPC1	O15118-1.2	E61P	Neutral	0.493
NPC1	O15118-1.2	E61Q	Neutral	0.277
NPC1	O15118-1.2	E61R	Pathogenic	0.509
NPC1	O15118-1.2	E61S	Neutral	0.485
NPC1	O15118-1.2	E61T	Pathogenic	0.526
NPC1	O15118-1.2	E61V	Pathogenic	0.525
NPC1	O15118-1.2	E61W	Pathogenic	0.609
NPC1	O15118-1.2	E61Y	Pathogenic	0.588
NPC1	O15118-1.2	L62A	Neutral	0.384
NPC1	O15118-1.2	L62C	Neutral	0.41
NPC1	O15118-1.2	L62D	Pathogenic	0.546
NPC1	O15118-1.2	L62E	Neutral	0.433
NPC1	O15118-1.2	L62F	Neutral	0.331
NPC1	O15118-1.2	L62G	Pathogenic	0.668
NPC1	O15118-1.2	L62H	Neutral	0.483
NPC1	O15118-1.2	L62I	Neutral	0.176
NPC1	O15118-1.2	L62K	Neutral	0.311
NPC1	O15118-1.2	L62M	Neutral	0.159
NPC1	O15118-1.2	L62N	Neutral	0.456
NPC1	O15118-1.2	L62P	Pathogenic	0.574
NPC1	O15118-1.2	L62Q	Neutral	0.367
NPC1	O15118-1.2	L62R	Neutral	0.327
NPC1	O15118-1.2	L62S	Neutral	0.441
NPC1	O15118-1.2	L62T	Neutral	0.344
NPC1	O15118-1.2	L62V	Neutral	0.237
NPC1	O15118-1.2	L62W	Pathogenic	0.521
NPC1	O15118-1.2	L62Y	Neutral	0.378
NPC1	O15118-1.2	C63A	Pathogenic	0.705
NPC1	O15118-1.2	C63D	Pathogenic	0.83
NPC1	O15118-1.2	C63E	Pathogenic	0.893
NPC1	O15118-1.2	C63F	Pathogenic	0.856
NPC1	O15118-1.2	C63G	Pathogenic	0.885
NPC1	O15118-1.2	C63H	Pathogenic	0.886
NPC1	O15118-1.2	C63I	Pathogenic	0.79
NPC1	O15118-1.2	C63K	Pathogenic	0.855
NPC1	O15118-1.2	C63L	Pathogenic	0.795
NPC1	O15118-1.2	C63M	Pathogenic	0.819
NPC1	O15118-1.2	C63N	Pathogenic	0.842
NPC1	O15118-1.2	C63P	Pathogenic	0.888
NPC1	O15118-1.2	C63Q	Pathogenic	0.871
NPC1	O15118-1.2	C63R	Pathogenic	0.864
NPC1	O15118-1.2	C63S	Pathogenic	0.751
NPC1	O15118-1.2	C63T	Pathogenic	0.763
NPC1	O15118-1.2	C63V	Pathogenic	0.803
NPC1	O15118-1.2	C63W	Pathogenic	0.858
NPC1	O15118-1.2	C63Y	Pathogenic	0.889
NPC1	O15118-1.2	P64A	Pathogenic	0.908
NPC1	O15118-1.2	P64C	Pathogenic	0.952
NPC1	O15118-1.2	P64D	Pathogenic	0.858
NPC1	O15118-1.2	P64E	Pathogenic	0.876
NPC1	O15118-1.2	P64F	Pathogenic	0.967
NPC1	O15118-1.2	P64G	Pathogenic	0.936
NPC1	O15118-1.2	P64H	Pathogenic	0.934
NPC1	O15118-1.2	P64I	Pathogenic	0.948
NPC1	O15118-1.2	P64K	Pathogenic	0.88
NPC1	O15118-1.2	P64L	Pathogenic	0.95
NPC1	O15118-1.2	P64M	Pathogenic	0.938
NPC1	O15118-1.2	P64N	Pathogenic	0.907
NPC1	O15118-1.2	P64Q	Pathogenic	0.893
NPC1	O15118-1.2	P64R	Pathogenic	0.921
NPC1	O15118-1.2	P64S	Pathogenic	0.895
NPC1	O15118-1.2	P64T	Pathogenic	0.896
NPC1	O15118-1.2	P64V	Pathogenic	0.931
NPC1	O15118-1.2	P64W	Pathogenic	0.967
NPC1	O15118-1.2	P64Y	Pathogenic	0.964
NPC1	O15118-1.2	G65A	Neutral	0.312
NPC1	O15118-1.2	G65C	Pathogenic	0.564
NPC1	O15118-1.2	G65D	Neutral	0.398
NPC1	O15118-1.2	G65E	Pathogenic	0.531
NPC1	O15118-1.2	G65F	Pathogenic	0.571
NPC1	O15118-1.2	G65H	Pathogenic	0.586
NPC1	O15118-1.2	G65I	Pathogenic	0.645
NPC1	O15118-1.2	G65K	Pathogenic	0.541
NPC1	O15118-1.2	G65L	Pathogenic	0.653
NPC1	O15118-1.2	G65M	Pathogenic	0.599
NPC1	O15118-1.2	G65N	Neutral	0.329
NPC1	O15118-1.2	G65P	Neutral	0.496
NPC1	O15118-1.2	G65Q	Pathogenic	0.573
NPC1	O15118-1.2	G65R	Pathogenic	0.559
NPC1	O15118-1.2	G65S	Neutral	0.339
NPC1	O15118-1.2	G65T	Pathogenic	0.538
NPC1	O15118-1.2	G65V	Pathogenic	0.573
NPC1	O15118-1.2	G65W	Neutral	0.479
NPC1	O15118-1.2	G65Y	Pathogenic	0.645
NPC1	O15118-1.2	F66A	Pathogenic	0.59
NPC1	O15118-1.2	F66C	Pathogenic	0.616
NPC1	O15118-1.2	F66D	Pathogenic	0.561
NPC1	O15118-1.2	F66E	Pathogenic	0.545
NPC1	O15118-1.2	F66G	Pathogenic	0.682
NPC1	O15118-1.2	F66H	Neutral	0.404
NPC1	O15118-1.2	F66I	Neutral	0.434
NPC1	O15118-1.2	F66K	Neutral	0.477
NPC1	O15118-1.2	F66L	Neutral	0.428
NPC1	O15118-1.2	F66M	Neutral	0.39
NPC1	O15118-1.2	F66N	Pathogenic	0.568
NPC1	O15118-1.2	F66P	Pathogenic	0.756
NPC1	O15118-1.2	F66Q	Pathogenic	0.572
NPC1	O15118-1.2	F66R	Neutral	0.495
NPC1	O15118-1.2	F66S	Pathogenic	0.553
NPC1	O15118-1.2	F66T	Pathogenic	0.547
NPC1	O15118-1.2	F66V	Pathogenic	0.513
NPC1	O15118-1.2	F66W	Neutral	0.333
NPC1	O15118-1.2	F66Y	Neutral	0.151
NPC1	O15118-1.2	F67A	Neutral	0.361
NPC1	O15118-1.2	F67C	Neutral	0.387
NPC1	O15118-1.2	F67D	Neutral	0.335
NPC1	O15118-1.2	F67E	Neutral	0.32
NPC1	O15118-1.2	F67G	Neutral	0.457
NPC1	O15118-1.2	F67H	Neutral	0.211
NPC1	O15118-1.2	F67I	Neutral	0.232
NPC1	O15118-1.2	F67K	Neutral	0.264
NPC1	O15118-1.2	F67L	Neutral	0.228
NPC1	O15118-1.2	F67M	Neutral	0.201
NPC1	O15118-1.2	F67N	Neutral	0.341
NPC1	O15118-1.2	F67P	Pathogenic	0.55
NPC1	O15118-1.2	F67Q	Neutral	0.345
NPC1	O15118-1.2	F67R	Neutral	0.278
NPC1	O15118-1.2	F67S	Neutral	0.327
NPC1	O15118-1.2	F67T	Neutral	0.322
NPC1	O15118-1.2	F67V	Neutral	0.293
NPC1	O15118-1.2	F67W	Neutral	0.164
NPC1	O15118-1.2	F67Y	Neutral	0.066
NPC1	O15118-1.2	F68A	Neutral	0.384
NPC1	O15118-1.2	F68C	Neutral	0.41
NPC1	O15118-1.2	F68D	Neutral	0.356
NPC1	O15118-1.2	F68E	Neutral	0.341
NPC1	O15118-1.2	F68G	Neutral	0.481
NPC1	O15118-1.2	F68H	Neutral	0.227
NPC1	O15118-1.2	F68I	Neutral	0.249
NPC1	O15118-1.2	F68K	Neutral	0.283
NPC1	O15118-1.2	F68L	Neutral	0.245
NPC1	O15118-1.2	F68M	Neutral	0.217
NPC1	O15118-1.2	F68N	Neutral	0.362
NPC1	O15118-1.2	F68P	Pathogenic	0.573
NPC1	O15118-1.2	F68Q	Neutral	0.366
NPC1	O15118-1.2	F68R	Neutral	0.298
NPC1	O15118-1.2	F68S	Neutral	0.349
NPC1	O15118-1.2	F68T	Neutral	0.343
NPC1	O15118-1.2	F68V	Neutral	0.313
NPC1	O15118-1.2	F68W	Neutral	0.177
NPC1	O15118-1.2	F68Y	Neutral	0.072
NPC1	O15118-1.2	G69A	Neutral	0.46
NPC1	O15118-1.2	G69C	Pathogenic	0.709
NPC1	O15118-1.2	G69D	Pathogenic	0.555
NPC1	O15118-1.2	G69E	Pathogenic	0.681
NPC1	O15118-1.2	G69F	Pathogenic	0.715
NPC1	O15118-1.2	G69H	Pathogenic	0.727
NPC1	O15118-1.2	G69I	Pathogenic	0.774
NPC1	O15118-1.2	G69K	Pathogenic	0.69
NPC1	O15118-1.2	G69L	Pathogenic	0.78
NPC1	O15118-1.2	G69M	Pathogenic	0.738
NPC1	O15118-1.2	G69N	Neutral	0.48
NPC1	O15118-1.2	G69P	Pathogenic	0.649
NPC1	O15118-1.2	G69Q	Pathogenic	0.716
NPC1	O15118-1.2	G69R	Pathogenic	0.705
NPC1	O15118-1.2	G69S	Neutral	0.492
NPC1	O15118-1.2	G69T	Pathogenic	0.687
NPC1	O15118-1.2	G69V	Pathogenic	0.716
NPC1	O15118-1.2	G69W	Pathogenic	0.634
NPC1	O15118-1.2	G69Y	Pathogenic	0.774
NPC1	O15118-1.2	N70A	Neutral	0.283
NPC1	O15118-1.2	N70C	Neutral	0.292
NPC1	O15118-1.2	N70D	Neutral	0.121
NPC1	O15118-1.2	N70E	Neutral	0.181
NPC1	O15118-1.2	N70F	Neutral	0.274
NPC1	O15118-1.2	N70G	Neutral	0.185
NPC1	O15118-1.2	N70H	Neutral	0.112
NPC1	O15118-1.2	N70I	Neutral	0.26
NPC1	O15118-1.2	N70K	Neutral	0.187
NPC1	O15118-1.2	N70L	Neutral	0.266
NPC1	O15118-1.2	N70M	Neutral	0.224
NPC1	O15118-1.2	N70P	Neutral	0.23
NPC1	O15118-1.2	N70Q	Neutral	0.169
NPC1	O15118-1.2	N70R	Neutral	0.199
NPC1	O15118-1.2	N70S	Neutral	0.118
NPC1	O15118-1.2	N70T	Neutral	0.137
NPC1	O15118-1.2	N70V	Neutral	0.275
NPC1	O15118-1.2	N70W	Neutral	0.36
NPC1	O15118-1.2	N70Y	Neutral	0.259
NPC1	O15118-1.2	V71A	Neutral	0.196
NPC1	O15118-1.2	V71C	Neutral	0.285
NPC1	O15118-1.2	V71D	Neutral	0.319
NPC1	O15118-1.2	V71E	Neutral	0.238
NPC1	O15118-1.2	V71F	Neutral	0.276
NPC1	O15118-1.2	V71G	Neutral	0.44
NPC1	O15118-1.2	V71H	Neutral	0.386
NPC1	O15118-1.2	V71I	Neutral	0.071
NPC1	O15118-1.2	V71K	Neutral	0.246
NPC1	O15118-1.2	V71L	Neutral	0.145
NPC1	O15118-1.2	V71M	Neutral	0.166
NPC1	O15118-1.2	V71N	Neutral	0.324
NPC1	O15118-1.2	V71P	Neutral	0.344
NPC1	O15118-1.2	V71Q	Neutral	0.27
NPC1	O15118-1.2	V71R	Neutral	0.34
NPC1	O15118-1.2	V71S	Neutral	0.312
NPC1	O15118-1.2	V71T	Neutral	0.17
NPC1	O15118-1.2	V71W	Neutral	0.456
NPC1	O15118-1.2	V71Y	Neutral	0.305
NPC1	O15118-1.2	S72A	Neutral	0.174
NPC1	O15118-1.2	S72C	Neutral	0.275
NPC1	O15118-1.2	S72D	Neutral	0.226
NPC1	O15118-1.2	S72E	Neutral	0.254
NPC1	O15118-1.2	S72F	Neutral	0.365
NPC1	O15118-1.2	S72G	Neutral	0.278
NPC1	O15118-1.2	S72H	Neutral	0.379
NPC1	O15118-1.2	S72I	Neutral	0.348
NPC1	O15118-1.2	S72K	Neutral	0.262
NPC1	O15118-1.2	S72L	Neutral	0.356
NPC1	O15118-1.2	S72M	Neutral	0.305
NPC1	O15118-1.2	S72N	Neutral	0.178
NPC1	O15118-1.2	S72P	Neutral	0.298
NPC1	O15118-1.2	S72Q	Neutral	0.287
NPC1	O15118-1.2	S72R	Neutral	0.36
NPC1	O15118-1.2	S72T	Neutral	0.189
NPC1	O15118-1.2	S72V	Neutral	0.367
NPC1	O15118-1.2	S72W	Neutral	0.462
NPC1	O15118-1.2	S72Y	Neutral	0.44
NPC1	O15118-1.2	L73A	Neutral	0.416
NPC1	O15118-1.2	L73C	Neutral	0.443
NPC1	O15118-1.2	L73D	Pathogenic	0.578
NPC1	O15118-1.2	L73E	Neutral	0.466
NPC1	O15118-1.2	L73F	Neutral	0.361
NPC1	O15118-1.2	L73G	Pathogenic	0.697
NPC1	O15118-1.2	L73H	Pathogenic	0.516
NPC1	O15118-1.2	L73I	Neutral	0.196
NPC1	O15118-1.2	L73K	Neutral	0.34
NPC1	O15118-1.2	L73M	Neutral	0.177
NPC1	O15118-1.2	L73N	Neutral	0.489
NPC1	O15118-1.2	L73P	Pathogenic	0.606
NPC1	O15118-1.2	L73Q	Neutral	0.398
NPC1	O15118-1.2	L73R	Neutral	0.357
NPC1	O15118-1.2	L73S	Neutral	0.474
NPC1	O15118-1.2	L73T	Neutral	0.374
NPC1	O15118-1.2	L73V	Neutral	0.261
NPC1	O15118-1.2	L73W	Pathogenic	0.554
NPC1	O15118-1.2	L73Y	Neutral	0.41
NPC1	O15118-1.2	C74A	Pathogenic	0.773
NPC1	O15118-1.2	C74D	Pathogenic	0.874
NPC1	O15118-1.2	C74E	Pathogenic	0.923
NPC1	O15118-1.2	C74F	Pathogenic	0.894
NPC1	O15118-1.2	C74G	Pathogenic	0.917
NPC1	O15118-1.2	C74H	Pathogenic	0.917
NPC1	O15118-1.2	C74I	Pathogenic	0.843
NPC1	O15118-1.2	C74K	Pathogenic	0.894
NPC1	O15118-1.2	C74L	Pathogenic	0.847
NPC1	O15118-1.2	C74M	Pathogenic	0.866
NPC1	O15118-1.2	C74N	Pathogenic	0.884
NPC1	O15118-1.2	C74P	Pathogenic	0.919
NPC1	O15118-1.2	C74Q	Pathogenic	0.906
NPC1	O15118-1.2	C74R	Pathogenic	0.901
NPC1	O15118-1.2	C74S	Pathogenic	0.812
NPC1	O15118-1.2	C74T	Pathogenic	0.821
NPC1	O15118-1.2	C74V	Pathogenic	0.853
NPC1	O15118-1.2	C74W	Pathogenic	0.896
NPC1	O15118-1.2	C74Y	Pathogenic	0.919
NPC1	O15118-1.2	C75A	Pathogenic	0.754
NPC1	O15118-1.2	C75D	Pathogenic	0.862
NPC1	O15118-1.2	C75E	Pathogenic	0.915
NPC1	O15118-1.2	C75F	Pathogenic	0.884
NPC1	O15118-1.2	C75G	Pathogenic	0.908
NPC1	O15118-1.2	C75H	Pathogenic	0.909
NPC1	O15118-1.2	C75I	Pathogenic	0.828
NPC1	O15118-1.2	C75K	Pathogenic	0.884
NPC1	O15118-1.2	C75L	Pathogenic	0.833
NPC1	O15118-1.2	C75M	Pathogenic	0.854
NPC1	O15118-1.2	C75N	Pathogenic	0.872
NPC1	O15118-1.2	C75P	Pathogenic	0.911
NPC1	O15118-1.2	C75Q	Pathogenic	0.896
NPC1	O15118-1.2	C75R	Pathogenic	0.891
NPC1	O15118-1.2	C75S	Pathogenic	0.795
NPC1	O15118-1.2	C75T	Pathogenic	0.805
NPC1	O15118-1.2	C75V	Pathogenic	0.839
NPC1	O15118-1.2	C75W	Pathogenic	0.886
NPC1	O15118-1.2	C75Y	Pathogenic	0.911
NPC1	O15118-1.2	D76A	Pathogenic	0.851
NPC1	O15118-1.2	D76C	Pathogenic	0.856
NPC1	O15118-1.2	D76E	Pathogenic	0.616
NPC1	O15118-1.2	D76F	Pathogenic	0.852
NPC1	O15118-1.2	D76G	Pathogenic	0.828
NPC1	O15118-1.2	D76H	Pathogenic	0.807
NPC1	O15118-1.2	D76I	Pathogenic	0.843
NPC1	O15118-1.2	D76K	Pathogenic	0.853
NPC1	O15118-1.2	D76L	Pathogenic	0.891
NPC1	O15118-1.2	D76M	Pathogenic	0.867
NPC1	O15118-1.2	D76N	Pathogenic	0.683
NPC1	O15118-1.2	D76P	Pathogenic	0.746
NPC1	O15118-1.2	D76Q	Pathogenic	0.757
NPC1	O15118-1.2	D76R	Pathogenic	0.902
NPC1	O15118-1.2	D76S	Pathogenic	0.74
NPC1	O15118-1.2	D76T	Pathogenic	0.775
NPC1	O15118-1.2	D76V	Pathogenic	0.854
NPC1	O15118-1.2	D76W	Pathogenic	0.896
NPC1	O15118-1.2	D76Y	Pathogenic	0.888
NPC1	O15118-1.2	V77A	Neutral	0.232
NPC1	O15118-1.2	V77C	Neutral	0.331
NPC1	O15118-1.2	V77D	Neutral	0.367
NPC1	O15118-1.2	V77E	Neutral	0.279
NPC1	O15118-1.2	V77F	Neutral	0.321
NPC1	O15118-1.2	V77G	Neutral	0.493
NPC1	O15118-1.2	V77H	Neutral	0.438
NPC1	O15118-1.2	V77I	Neutral	0.086
NPC1	O15118-1.2	V77K	Neutral	0.288
NPC1	O15118-1.2	V77L	Neutral	0.174
NPC1	O15118-1.2	V77M	Neutral	0.197
NPC1	O15118-1.2	V77N	Neutral	0.373
NPC1	O15118-1.2	V77P	Neutral	0.394
NPC1	O15118-1.2	V77Q	Neutral	0.315
NPC1	O15118-1.2	V77R	Neutral	0.39
NPC1	O15118-1.2	V77S	Neutral	0.359
NPC1	O15118-1.2	V77T	Neutral	0.202
NPC1	O15118-1.2	V77W	Pathogenic	0.51
NPC1	O15118-1.2	V77Y	Neutral	0.352
NPC1	O15118-1.2	R78A	Neutral	0.158
NPC1	O15118-1.2	R78C	Neutral	0.224
NPC1	O15118-1.2	R78D	Neutral	0.254
NPC1	O15118-1.2	R78E	Neutral	0.119
NPC1	O15118-1.2	R78F	Neutral	0.141
NPC1	O15118-1.2	R78G	Neutral	0.255
NPC1	O15118-1.2	R78H	Neutral	0.09
NPC1	O15118-1.2	R78I	Neutral	0.149
NPC1	O15118-1.2	R78K	Neutral	0.057
NPC1	O15118-1.2	R78L	Neutral	0.11
NPC1	O15118-1.2	R78M	Neutral	0.089
NPC1	O15118-1.2	R78N	Neutral	0.126
NPC1	O15118-1.2	R78P	Neutral	0.173
NPC1	O15118-1.2	R78Q	Neutral	0.072
NPC1	O15118-1.2	R78S	Neutral	0.169
NPC1	O15118-1.2	R78T	Neutral	0.14
NPC1	O15118-1.2	R78V	Neutral	0.192
NPC1	O15118-1.2	R78W	Neutral	0.125
NPC1	O15118-1.2	R78Y	Neutral	0.124
NPC1	O15118-1.2	Q79A	Pathogenic	0.86
NPC1	O15118-1.2	Q79C	Pathogenic	0.905
NPC1	O15118-1.2	Q79D	Pathogenic	0.782
NPC1	O15118-1.2	Q79E	Pathogenic	0.609
NPC1	O15118-1.2	Q79F	Pathogenic	0.874
NPC1	O15118-1.2	Q79G	Pathogenic	0.918
NPC1	O15118-1.2	Q79H	Pathogenic	0.774
NPC1	O15118-1.2	Q79I	Pathogenic	0.866
NPC1	O15118-1.2	Q79K	Pathogenic	0.692
NPC1	O15118-1.2	Q79L	Pathogenic	0.82
NPC1	O15118-1.2	Q79M	Pathogenic	0.711
NPC1	O15118-1.2	Q79N	Pathogenic	0.787
NPC1	O15118-1.2	Q79P	Pathogenic	0.824
NPC1	O15118-1.2	Q79R	Pathogenic	0.707
NPC1	O15118-1.2	Q79S	Pathogenic	0.819
NPC1	O15118-1.2	Q79T	Pathogenic	0.842
NPC1	O15118-1.2	Q79V	Pathogenic	0.842
NPC1	O15118-1.2	Q79W	Pathogenic	0.828
NPC1	O15118-1.2	Q79Y	Pathogenic	0.814
NPC1	O15118-1.2	L80A	Pathogenic	0.798
NPC1	O15118-1.2	L80C	Pathogenic	0.815
NPC1	O15118-1.2	L80D	Pathogenic	0.884
NPC1	O15118-1.2	L80E	Pathogenic	0.829
NPC1	O15118-1.2	L80F	Pathogenic	0.758
NPC1	O15118-1.2	L80G	Pathogenic	0.927
NPC1	O15118-1.2	L80H	Pathogenic	0.855
NPC1	O15118-1.2	L80I	Pathogenic	0.574
NPC1	O15118-1.2	L80K	Pathogenic	0.741
NPC1	O15118-1.2	L80M	Pathogenic	0.544
NPC1	O15118-1.2	L80N	Pathogenic	0.841
NPC1	O15118-1.2	L80P	Pathogenic	0.895
NPC1	O15118-1.2	L80Q	Pathogenic	0.786
NPC1	O15118-1.2	L80R	Pathogenic	0.754
NPC1	O15118-1.2	L80S	Pathogenic	0.833
NPC1	O15118-1.2	L80T	Pathogenic	0.768
NPC1	O15118-1.2	L80V	Pathogenic	0.662
NPC1	O15118-1.2	L80W	Pathogenic	0.873
NPC1	O15118-1.2	L80Y	Pathogenic	0.794
NPC1	O15118-1.2	Q81A	Neutral	0.283
NPC1	O15118-1.2	Q81C	Neutral	0.378
NPC1	O15118-1.2	Q81D	Neutral	0.187
NPC1	O15118-1.2	Q81E	Neutral	0.091
NPC1	O15118-1.2	Q81F	Neutral	0.308
NPC1	O15118-1.2	Q81G	Neutral	0.419
NPC1	O15118-1.2	Q81H	Neutral	0.18
NPC1	O15118-1.2	Q81I	Neutral	0.293
NPC1	O15118-1.2	Q81K	Neutral	0.126
NPC1	O15118-1.2	Q81L	Neutral	0.226
NPC1	O15118-1.2	Q81M	Neutral	0.136
NPC1	O15118-1.2	Q81N	Neutral	0.191
NPC1	O15118-1.2	Q81P	Neutral	0.23
NPC1	O15118-1.2	Q81R	Neutral	0.134
NPC1	O15118-1.2	Q81S	Neutral	0.225
NPC1	O15118-1.2	Q81T	Neutral	0.255
NPC1	O15118-1.2	Q81V	Neutral	0.254
NPC1	O15118-1.2	Q81W	Neutral	0.235
NPC1	O15118-1.2	Q81Y	Neutral	0.219
NPC1	O15118-1.2	T82A	Pathogenic	0.662
NPC1	O15118-1.2	T82C	Pathogenic	0.672
NPC1	O15118-1.2	T82D	Pathogenic	0.643
NPC1	O15118-1.2	T82E	Pathogenic	0.672
NPC1	O15118-1.2	T82F	Pathogenic	0.74
NPC1	O15118-1.2	T82G	Pathogenic	0.816
NPC1	O15118-1.2	T82H	Pathogenic	0.804
NPC1	O15118-1.2	T82I	Pathogenic	0.643
NPC1	O15118-1.2	T82K	Pathogenic	0.68
NPC1	O15118-1.2	T82L	Pathogenic	0.651
NPC1	O15118-1.2	T82M	Pathogenic	0.686
NPC1	O15118-1.2	T82N	Pathogenic	0.565
NPC1	O15118-1.2	T82P	Pathogenic	0.686
NPC1	O15118-1.2	T82Q	Pathogenic	0.708
NPC1	O15118-1.2	T82R	Pathogenic	0.696
NPC1	O15118-1.2	T82S	Pathogenic	0.542
NPC1	O15118-1.2	T82V	Pathogenic	0.57
NPC1	O15118-1.2	T82W	Pathogenic	0.743
NPC1	O15118-1.2	T82Y	Pathogenic	0.795
NPC1	O15118-1.2	L83A	Pathogenic	0.806
NPC1	O15118-1.2	L83C	Pathogenic	0.823
NPC1	O15118-1.2	L83D	Pathogenic	0.889
NPC1	O15118-1.2	L83E	Pathogenic	0.836
NPC1	O15118-1.2	L83F	Pathogenic	0.768
NPC1	O15118-1.2	L83G	Pathogenic	0.931
NPC1	O15118-1.2	L83H	Pathogenic	0.862
NPC1	O15118-1.2	L83I	Pathogenic	0.587
NPC1	O15118-1.2	L83K	Pathogenic	0.751
NPC1	O15118-1.2	L83M	Pathogenic	0.558
NPC1	O15118-1.2	L83N	Pathogenic	0.848
NPC1	O15118-1.2	L83P	Pathogenic	0.9
NPC1	O15118-1.2	L83Q	Pathogenic	0.795
NPC1	O15118-1.2	L83R	Pathogenic	0.764
NPC1	O15118-1.2	L83S	Pathogenic	0.841
NPC1	O15118-1.2	L83T	Pathogenic	0.778
NPC1	O15118-1.2	L83V	Pathogenic	0.674
NPC1	O15118-1.2	L83W	Pathogenic	0.879
NPC1	O15118-1.2	L83Y	Pathogenic	0.802
NPC1	O15118-1.2	K84A	Neutral	0.48
NPC1	O15118-1.2	K84C	Pathogenic	0.588
NPC1	O15118-1.2	K84D	Pathogenic	0.533
NPC1	O15118-1.2	K84E	Neutral	0.312
NPC1	O15118-1.2	K84F	Neutral	0.448
NPC1	O15118-1.2	K84G	Pathogenic	0.628
NPC1	O15118-1.2	K84H	Neutral	0.419
NPC1	O15118-1.2	K84I	Neutral	0.463
NPC1	O15118-1.2	K84L	Neutral	0.377
NPC1	O15118-1.2	K84M	Neutral	0.325
NPC1	O15118-1.2	K84N	Neutral	0.416
NPC1	O15118-1.2	K84P	Neutral	0.412
NPC1	O15118-1.2	K84Q	Neutral	0.277
NPC1	O15118-1.2	K84R	Neutral	0.242
NPC1	O15118-1.2	K84S	Neutral	0.405
NPC1	O15118-1.2	K84T	Neutral	0.445
NPC1	O15118-1.2	K84V	Neutral	0.444
NPC1	O15118-1.2	K84W	Neutral	0.451
NPC1	O15118-1.2	K84Y	Neutral	0.429
NPC1	O15118-1.2	D85A	Neutral	0.167
NPC1	O15118-1.2	D85C	Neutral	0.173
NPC1	O15118-1.2	D85E	Neutral	0.054
NPC1	O15118-1.2	D85F	Neutral	0.169
NPC1	O15118-1.2	D85G	Neutral	0.145
NPC1	O15118-1.2	D85H	Neutral	0.128
NPC1	O15118-1.2	D85I	Neutral	0.159
NPC1	O15118-1.2	D85K	Neutral	0.17
NPC1	O15118-1.2	D85L	Neutral	0.224
NPC1	O15118-1.2	D85M	Neutral	0.186
NPC1	O15118-1.2	D85N	Neutral	0.071
NPC1	O15118-1.2	D85P	Neutral	0.094
NPC1	O15118-1.2	D85Q	Neutral	0.099
NPC1	O15118-1.2	D85R	Neutral	0.245
NPC1	O15118-1.2	D85S	Neutral	0.091
NPC1	O15118-1.2	D85T	Neutral	0.108
NPC1	O15118-1.2	D85V	Neutral	0.17
NPC1	O15118-1.2	D85W	Neutral	0.233
NPC1	O15118-1.2	D85Y	Neutral	0.217
NPC1	O15118-1.2	N86A	Pathogenic	0.812
NPC1	O15118-1.2	N86C	Pathogenic	0.819
NPC1	O15118-1.2	N86D	Pathogenic	0.601
NPC1	O15118-1.2	N86E	Pathogenic	0.708
NPC1	O15118-1.2	N86F	Pathogenic	0.805
NPC1	O15118-1.2	N86G	Pathogenic	0.713
NPC1	O15118-1.2	N86H	Pathogenic	0.58
NPC1	O15118-1.2	N86I	Pathogenic	0.794
NPC1	O15118-1.2	N86K	Pathogenic	0.716
NPC1	O15118-1.2	N86L	Pathogenic	0.799
NPC1	O15118-1.2	N86M	Pathogenic	0.76
NPC1	O15118-1.2	N86P	Pathogenic	0.767
NPC1	O15118-1.2	N86Q	Pathogenic	0.69
NPC1	O15118-1.2	N86R	Pathogenic	0.731
NPC1	O15118-1.2	N86S	Pathogenic	0.595
NPC1	O15118-1.2	N86T	Pathogenic	0.635
NPC1	O15118-1.2	N86V	Pathogenic	0.806
NPC1	O15118-1.2	N86W	Pathogenic	0.861
NPC1	O15118-1.2	N86Y	Pathogenic	0.793
NPC1	O15118-1.2	L87A	Pathogenic	0.503
NPC1	O15118-1.2	L87C	Pathogenic	0.53
NPC1	O15118-1.2	L87D	Pathogenic	0.661
NPC1	O15118-1.2	L87E	Pathogenic	0.554
NPC1	O15118-1.2	L87F	Neutral	0.446
NPC1	O15118-1.2	L87G	Pathogenic	0.765
NPC1	O15118-1.2	L87H	Pathogenic	0.603
NPC1	O15118-1.2	L87I	Neutral	0.257
NPC1	O15118-1.2	L87K	Neutral	0.423
NPC1	O15118-1.2	L87M	Neutral	0.235
NPC1	O15118-1.2	L87N	Pathogenic	0.576
NPC1	O15118-1.2	L87P	Pathogenic	0.686
NPC1	O15118-1.2	L87Q	Neutral	0.485
NPC1	O15118-1.2	L87R	Neutral	0.441
NPC1	O15118-1.2	L87S	Pathogenic	0.562
NPC1	O15118-1.2	L87T	Neutral	0.46
NPC1	O15118-1.2	L87V	Neutral	0.335
NPC1	O15118-1.2	L87W	Pathogenic	0.639
NPC1	O15118-1.2	L87Y	Neutral	0.497
NPC1	O15118-1.2	Q88A	Neutral	0.499
NPC1	O15118-1.2	Q88C	Pathogenic	0.605
NPC1	O15118-1.2	Q88D	Neutral	0.368
NPC1	O15118-1.2	Q88E	Neutral	0.201
NPC1	O15118-1.2	Q88F	Pathogenic	0.529
NPC1	O15118-1.2	Q88G	Pathogenic	0.645
NPC1	O15118-1.2	Q88H	Neutral	0.356
NPC1	O15118-1.2	Q88I	Pathogenic	0.512
NPC1	O15118-1.2	Q88K	Neutral	0.266
NPC1	O15118-1.2	Q88L	Neutral	0.424
NPC1	O15118-1.2	Q88M	Neutral	0.285
NPC1	O15118-1.2	Q88N	Neutral	0.374
NPC1	O15118-1.2	Q88P	Neutral	0.43
NPC1	O15118-1.2	Q88R	Neutral	0.281
NPC1	O15118-1.2	Q88S	Neutral	0.423
NPC1	O15118-1.2	Q88T	Neutral	0.464
NPC1	O15118-1.2	Q88V	Neutral	0.462
NPC1	O15118-1.2	Q88W	Neutral	0.437
NPC1	O15118-1.2	Q88Y	Neutral	0.415
NPC1	O15118-1.2	L89A	Pathogenic	0.689
NPC1	O15118-1.2	L89C	Pathogenic	0.712
NPC1	O15118-1.2	L89D	Pathogenic	0.81
NPC1	O15118-1.2	L89E	Pathogenic	0.73
NPC1	O15118-1.2	L89F	Pathogenic	0.637
NPC1	O15118-1.2	L89G	Pathogenic	0.877
NPC1	O15118-1.2	L89H	Pathogenic	0.768
NPC1	O15118-1.2	L89I	Neutral	0.431
NPC1	O15118-1.2	L89K	Pathogenic	0.615
NPC1	O15118-1.2	L89M	Neutral	0.401
NPC1	O15118-1.2	L89N	Pathogenic	0.748
NPC1	O15118-1.2	L89P	Pathogenic	0.827
NPC1	O15118-1.2	L89Q	Pathogenic	0.673
NPC1	O15118-1.2	L89R	Pathogenic	0.633
NPC1	O15118-1.2	L89S	Pathogenic	0.737
NPC1	O15118-1.2	L89T	Pathogenic	0.65
NPC1	O15118-1.2	L89V	Pathogenic	0.524
NPC1	O15118-1.2	L89W	Pathogenic	0.794
NPC1	O15118-1.2	L89Y	Pathogenic	0.683
NPC1	O15118-1.2	P90A	Pathogenic	0.686
NPC1	O15118-1.2	P90C	Pathogenic	0.815
NPC1	O15118-1.2	P90D	Pathogenic	0.572
NPC1	O15118-1.2	P90E	Pathogenic	0.609
NPC1	O15118-1.2	P90F	Pathogenic	0.864
NPC1	O15118-1.2	P90G	Pathogenic	0.765
NPC1	O15118-1.2	P90H	Pathogenic	0.757
NPC1	O15118-1.2	P90I	Pathogenic	0.801
NPC1	O15118-1.2	P90K	Pathogenic	0.618
NPC1	O15118-1.2	P90L	Pathogenic	0.807
NPC1	O15118-1.2	P90M	Pathogenic	0.768
NPC1	O15118-1.2	P90N	Pathogenic	0.681
NPC1	O15118-1.2	P90Q	Pathogenic	0.648
NPC1	O15118-1.2	P90R	Pathogenic	0.719
NPC1	O15118-1.2	P90S	Pathogenic	0.652
NPC1	O15118-1.2	P90T	Pathogenic	0.655
NPC1	O15118-1.2	P90V	Pathogenic	0.748
NPC1	O15118-1.2	P90W	Pathogenic	0.866
NPC1	O15118-1.2	P90Y	Pathogenic	0.855
NPC1	O15118-1.2	L91A	Neutral	0.287
NPC1	O15118-1.2	L91C	Neutral	0.31
NPC1	O15118-1.2	L91D	Neutral	0.437
NPC1	O15118-1.2	L91E	Neutral	0.331
NPC1	O15118-1.2	L91F	Neutral	0.243
NPC1	O15118-1.2	L91G	Pathogenic	0.565
NPC1	O15118-1.2	L91H	Neutral	0.377
NPC1	O15118-1.2	L91I	Neutral	0.121
NPC1	O15118-1.2	L91K	Neutral	0.226
NPC1	O15118-1.2	L91M	Neutral	0.109
NPC1	O15118-1.2	L91N	Neutral	0.351
NPC1	O15118-1.2	L91P	Neutral	0.465
NPC1	O15118-1.2	L91Q	Neutral	0.272
NPC1	O15118-1.2	L91R	Neutral	0.239
NPC1	O15118-1.2	L91S	Neutral	0.338
NPC1	O15118-1.2	L91T	Neutral	0.253
NPC1	O15118-1.2	L91V	Neutral	0.167
NPC1	O15118-1.2	L91W	Neutral	0.413
NPC1	O15118-1.2	L91Y	Neutral	0.282
NPC1	O15118-1.2	Q92A	Pathogenic	0.69
NPC1	O15118-1.2	Q92C	Pathogenic	0.774
NPC1	O15118-1.2	Q92D	Pathogenic	0.565
NPC1	O15118-1.2	Q92E	Neutral	0.36
NPC1	O15118-1.2	Q92F	Pathogenic	0.716
NPC1	O15118-1.2	Q92G	Pathogenic	0.803
NPC1	O15118-1.2	Q92H	Pathogenic	0.553
NPC1	O15118-1.2	Q92I	Pathogenic	0.701
NPC1	O15118-1.2	Q92K	Neutral	0.448
NPC1	O15118-1.2	Q92L	Pathogenic	0.622
NPC1	O15118-1.2	Q92M	Neutral	0.471
NPC1	O15118-1.2	Q92N	Pathogenic	0.572
NPC1	O15118-1.2	Q92P	Pathogenic	0.628
NPC1	O15118-1.2	Q92R	Neutral	0.466
NPC1	O15118-1.2	Q92S	Pathogenic	0.621
NPC1	O15118-1.2	Q92T	Pathogenic	0.659
NPC1	O15118-1.2	Q92V	Pathogenic	0.658
NPC1	O15118-1.2	Q92W	Pathogenic	0.635
NPC1	O15118-1.2	Q92Y	Pathogenic	0.614
NPC1	O15118-1.2	F93A	Pathogenic	0.733
NPC1	O15118-1.2	F93C	Pathogenic	0.754
NPC1	O15118-1.2	F93D	Pathogenic	0.71
NPC1	O15118-1.2	F93E	Pathogenic	0.696
NPC1	O15118-1.2	F93G	Pathogenic	0.804
NPC1	O15118-1.2	F93H	Pathogenic	0.564
NPC1	O15118-1.2	F93I	Pathogenic	0.594
NPC1	O15118-1.2	F93K	Pathogenic	0.635
NPC1	O15118-1.2	F93L	Pathogenic	0.588
NPC1	O15118-1.2	F93M	Pathogenic	0.55
NPC1	O15118-1.2	F93N	Pathogenic	0.715
NPC1	O15118-1.2	F93P	Pathogenic	0.856
NPC1	O15118-1.2	F93Q	Pathogenic	0.719
NPC1	O15118-1.2	F93R	Pathogenic	0.652
NPC1	O15118-1.2	F93S	Pathogenic	0.703
NPC1	O15118-1.2	F93T	Pathogenic	0.698
NPC1	O15118-1.2	F93V	Pathogenic	0.668
NPC1	O15118-1.2	F93W	Neutral	0.488
NPC1	O15118-1.2	F93Y	Neutral	0.254
NPC1	O15118-1.2	L94A	Pathogenic	0.807
NPC1	O15118-1.2	L94C	Pathogenic	0.824
NPC1	O15118-1.2	L94D	Pathogenic	0.889
NPC1	O15118-1.2	L94E	Pathogenic	0.837
NPC1	O15118-1.2	L94F	Pathogenic	0.769
NPC1	O15118-1.2	L94G	Pathogenic	0.931
NPC1	O15118-1.2	L94H	Pathogenic	0.862
NPC1	O15118-1.2	L94I	Pathogenic	0.588
NPC1	O15118-1.2	L94K	Pathogenic	0.752
NPC1	O15118-1.2	L94M	Pathogenic	0.559
NPC1	O15118-1.2	L94N	Pathogenic	0.849
NPC1	O15118-1.2	L94P	Pathogenic	0.9
NPC1	O15118-1.2	L94Q	Pathogenic	0.795
NPC1	O15118-1.2	L94R	Pathogenic	0.765
NPC1	O15118-1.2	L94S	Pathogenic	0.841
NPC1	O15118-1.2	L94T	Pathogenic	0.778
NPC1	O15118-1.2	L94V	Pathogenic	0.675
NPC1	O15118-1.2	L94W	Pathogenic	0.88
NPC1	O15118-1.2	L94Y	Pathogenic	0.803
NPC1	O15118-1.2	S95A	Neutral	0.282
NPC1	O15118-1.2	S95C	Neutral	0.415
NPC1	O15118-1.2	S95D	Neutral	0.354
NPC1	O15118-1.2	S95E	Neutral	0.389
NPC1	O15118-1.2	S95F	Pathogenic	0.518
NPC1	O15118-1.2	S95G	Neutral	0.418
NPC1	O15118-1.2	S95H	Pathogenic	0.533
NPC1	O15118-1.2	S95I	Pathogenic	0.5
NPC1	O15118-1.2	S95K	Neutral	0.399
NPC1	O15118-1.2	S95L	Pathogenic	0.509
NPC1	O15118-1.2	S95M	Neutral	0.451
NPC1	O15118-1.2	S95N	Neutral	0.289
NPC1	O15118-1.2	S95P	Neutral	0.443
NPC1	O15118-1.2	S95Q	Neutral	0.43
NPC1	O15118-1.2	S95R	Pathogenic	0.512
NPC1	O15118-1.2	S95T	Neutral	0.304
NPC1	O15118-1.2	S95V	Pathogenic	0.52
NPC1	O15118-1.2	S95W	Pathogenic	0.616
NPC1	O15118-1.2	S95Y	Pathogenic	0.595
NPC1	O15118-1.2	R96A	Pathogenic	0.959
NPC1	O15118-1.2	R96C	Pathogenic	0.973
NPC1	O15118-1.2	R96D	Pathogenic	0.977
NPC1	O15118-1.2	R96E	Pathogenic	0.945
NPC1	O15118-1.2	R96F	Pathogenic	0.954
NPC1	O15118-1.2	R96G	Pathogenic	0.977
NPC1	O15118-1.2	R96H	Pathogenic	0.926
NPC1	O15118-1.2	R96I	Pathogenic	0.957
NPC1	O15118-1.2	R96K	Pathogenic	0.884
NPC1	O15118-1.2	R96L	Pathogenic	0.94
NPC1	O15118-1.2	R96M	Pathogenic	0.925
NPC1	O15118-1.2	R96N	Pathogenic	0.948
NPC1	O15118-1.2	R96P	Pathogenic	0.964
NPC1	O15118-1.2	R96Q	Pathogenic	0.908
NPC1	O15118-1.2	R96S	Pathogenic	0.962
NPC1	O15118-1.2	R96T	Pathogenic	0.954
NPC1	O15118-1.2	R96V	Pathogenic	0.968
NPC1	O15118-1.2	R96W	Pathogenic	0.947
NPC1	O15118-1.2	R96Y	Pathogenic	0.947
NPC1	O15118-1.2	C97A	Pathogenic	0.795
NPC1	O15118-1.2	C97D	Pathogenic	0.888
NPC1	O15118-1.2	C97E	Pathogenic	0.931
NPC1	O15118-1.2	C97F	Pathogenic	0.906
NPC1	O15118-1.2	C97G	Pathogenic	0.926
NPC1	O15118-1.2	C97H	Pathogenic	0.927
NPC1	O15118-1.2	C97I	Pathogenic	0.859
NPC1	O15118-1.2	C97K	Pathogenic	0.906
NPC1	O15118-1.2	C97L	Pathogenic	0.863
NPC1	O15118-1.2	C97M	Pathogenic	0.881
NPC1	O15118-1.2	C97N	Pathogenic	0.896
NPC1	O15118-1.2	C97P	Pathogenic	0.928
NPC1	O15118-1.2	C97Q	Pathogenic	0.916
NPC1	O15118-1.2	C97R	Pathogenic	0.912
NPC1	O15118-1.2	C97S	Pathogenic	0.831
NPC1	O15118-1.2	C97T	Pathogenic	0.839
NPC1	O15118-1.2	C97V	Pathogenic	0.869
NPC1	O15118-1.2	C97W	Pathogenic	0.907
NPC1	O15118-1.2	C97Y	Pathogenic	0.928
NPC1	O15118-1.2	P98A	Pathogenic	0.955
NPC1	O15118-1.2	P98C	Pathogenic	0.977
NPC1	O15118-1.2	P98D	Pathogenic	0.929
NPC1	O15118-1.2	P98E	Pathogenic	0.938
NPC1	O15118-1.2	P98F	Pathogenic	0.984
NPC1	O15118-1.2	P98G	Pathogenic	0.969
NPC1	O15118-1.2	P98H	Pathogenic	0.968
NPC1	O15118-1.2	P98I	Pathogenic	0.975
NPC1	O15118-1.2	P98K	Pathogenic	0.94
NPC1	O15118-1.2	P98L	Pathogenic	0.976
NPC1	O15118-1.2	P98M	Pathogenic	0.97
NPC1	O15118-1.2	P98N	Pathogenic	0.954
NPC1	O15118-1.2	P98Q	Pathogenic	0.947
NPC1	O15118-1.2	P98R	Pathogenic	0.961
NPC1	O15118-1.2	P98S	Pathogenic	0.948
NPC1	O15118-1.2	P98T	Pathogenic	0.949
NPC1	O15118-1.2	P98V	Pathogenic	0.967
NPC1	O15118-1.2	P98W	Pathogenic	0.984
NPC1	O15118-1.2	P98Y	Pathogenic	0.983
NPC1	O15118-1.2	S99A	Pathogenic	0.763
NPC1	O15118-1.2	S99C	Pathogenic	0.853
NPC1	O15118-1.2	S99D	Pathogenic	0.817
NPC1	O15118-1.2	S99E	Pathogenic	0.839
NPC1	O15118-1.2	S99F	Pathogenic	0.898
NPC1	O15118-1.2	S99G	Pathogenic	0.855
NPC1	O15118-1.2	S99H	Pathogenic	0.903
NPC1	O15118-1.2	S99I	Pathogenic	0.891
NPC1	O15118-1.2	S99K	Pathogenic	0.844
NPC1	O15118-1.2	S99L	Pathogenic	0.894
NPC1	O15118-1.2	S99M	Pathogenic	0.87
NPC1	O15118-1.2	S99N	Pathogenic	0.768
NPC1	O15118-1.2	S99P	Pathogenic	0.866
NPC1	O15118-1.2	S99Q	Pathogenic	0.86
NPC1	O15118-1.2	S99R	Pathogenic	0.896
NPC1	O15118-1.2	S99T	Pathogenic	0.781
NPC1	O15118-1.2	S99V	Pathogenic	0.898
NPC1	O15118-1.2	S99W	Pathogenic	0.929
NPC1	O15118-1.2	S99Y	Pathogenic	0.923
NPC1	O15118-1.2	C100A	Pathogenic	0.795
NPC1	O15118-1.2	C100D	Pathogenic	0.888
NPC1	O15118-1.2	C100E	Pathogenic	0.931
NPC1	O15118-1.2	C100F	Pathogenic	0.906
NPC1	O15118-1.2	C100G	Pathogenic	0.926
NPC1	O15118-1.2	C100H	Pathogenic	0.927
NPC1	O15118-1.2	C100I	Pathogenic	0.859
NPC1	O15118-1.2	C100K	Pathogenic	0.906
NPC1	O15118-1.2	C100L	Pathogenic	0.863
NPC1	O15118-1.2	C100M	Pathogenic	0.881
NPC1	O15118-1.2	C100N	Pathogenic	0.896
NPC1	O15118-1.2	C100P	Pathogenic	0.928
NPC1	O15118-1.2	C100Q	Pathogenic	0.916
NPC1	O15118-1.2	C100R	Pathogenic	0.912
NPC1	O15118-1.2	C100S	Pathogenic	0.831
NPC1	O15118-1.2	C100T	Pathogenic	0.839
NPC1	O15118-1.2	C100V	Pathogenic	0.869
NPC1	O15118-1.2	C100W	Pathogenic	0.907
NPC1	O15118-1.2	C100Y	Pathogenic	0.928
NPC1	O15118-1.2	F101A	Pathogenic	0.622
NPC1	O15118-1.2	F101C	Pathogenic	0.648
NPC1	O15118-1.2	F101D	Pathogenic	0.594
NPC1	O15118-1.2	F101E	Pathogenic	0.579
NPC1	O15118-1.2	F101G	Pathogenic	0.711
NPC1	O15118-1.2	F101H	Neutral	0.437
NPC1	O15118-1.2	F101I	Neutral	0.468
NPC1	O15118-1.2	F101K	Pathogenic	0.511
NPC1	O15118-1.2	F101L	Neutral	0.462
NPC1	O15118-1.2	F101M	Neutral	0.423
NPC1	O15118-1.2	F101N	Pathogenic	0.601
NPC1	O15118-1.2	F101P	Pathogenic	0.78
NPC1	O15118-1.2	F101Q	Pathogenic	0.605
NPC1	O15118-1.2	F101R	Pathogenic	0.529
NPC1	O15118-1.2	F101S	Pathogenic	0.586
NPC1	O15118-1.2	F101T	Pathogenic	0.581
NPC1	O15118-1.2	F101V	Pathogenic	0.546
NPC1	O15118-1.2	F101W	Neutral	0.363
NPC1	O15118-1.2	F101Y	Neutral	0.17
NPC1	O15118-1.2	Y102A	Neutral	0.453
NPC1	O15118-1.2	Y102C	Neutral	0.476
NPC1	O15118-1.2	Y102D	Neutral	0.424
NPC1	O15118-1.2	Y102E	Neutral	0.319
NPC1	O15118-1.2	Y102F	Neutral	0.07
NPC1	O15118-1.2	Y102G	Pathogenic	0.552
NPC1	O15118-1.2	Y102H	Neutral	0.109
NPC1	O15118-1.2	Y102I	Neutral	0.272
NPC1	O15118-1.2	Y102K	Neutral	0.262
NPC1	O15118-1.2	Y102L	Neutral	0.279
NPC1	O15118-1.2	Y102M	Neutral	0.311
NPC1	O15118-1.2	Y102N	Neutral	0.339
NPC1	O15118-1.2	Y102P	Pathogenic	0.548
NPC1	O15118-1.2	Y102Q	Neutral	0.262
NPC1	O15118-1.2	Y102R	Neutral	0.263
NPC1	O15118-1.2	Y102S	Neutral	0.416
NPC1	O15118-1.2	Y102T	Neutral	0.41
NPC1	O15118-1.2	Y102V	Neutral	0.337
NPC1	O15118-1.2	Y102W	Neutral	0.094
NPC1	O15118-1.2	N103A	Pathogenic	0.967
NPC1	O15118-1.2	N103C	Pathogenic	0.968
NPC1	O15118-1.2	N103D	Pathogenic	0.91
NPC1	O15118-1.2	N103E	Pathogenic	0.942
NPC1	O15118-1.2	N103F	Pathogenic	0.965
NPC1	O15118-1.2	N103G	Pathogenic	0.943
NPC1	O15118-1.2	N103H	Pathogenic	0.903
NPC1	O15118-1.2	N103I	Pathogenic	0.963
NPC1	O15118-1.2	N103K	Pathogenic	0.944
NPC1	O15118-1.2	N103L	Pathogenic	0.964
NPC1	O15118-1.2	N103M	Pathogenic	0.955
NPC1	O15118-1.2	N103P	Pathogenic	0.957
NPC1	O15118-1.2	N103Q	Pathogenic	0.937
NPC1	O15118-1.2	N103R	Pathogenic	0.948
NPC1	O15118-1.2	N103S	Pathogenic	0.908
NPC1	O15118-1.2	N103T	Pathogenic	0.921
NPC1	O15118-1.2	N103V	Pathogenic	0.965
NPC1	O15118-1.2	N103W	Pathogenic	0.976
NPC1	O15118-1.2	N103Y	Pathogenic	0.963
NPC1	O15118-1.2	L104A	Pathogenic	0.8
NPC1	O15118-1.2	L104C	Pathogenic	0.817
NPC1	O15118-1.2	L104D	Pathogenic	0.885
NPC1	O15118-1.2	L104E	Pathogenic	0.831
NPC1	O15118-1.2	L104F	Pathogenic	0.761
NPC1	O15118-1.2	L104G	Pathogenic	0.928
NPC1	O15118-1.2	L104H	Pathogenic	0.857
NPC1	O15118-1.2	L104I	Pathogenic	0.578
NPC1	O15118-1.2	L104K	Pathogenic	0.744
NPC1	O15118-1.2	L104M	Pathogenic	0.548
NPC1	O15118-1.2	L104N	Pathogenic	0.843
NPC1	O15118-1.2	L104P	Pathogenic	0.896
NPC1	O15118-1.2	L104Q	Pathogenic	0.788
NPC1	O15118-1.2	L104R	Pathogenic	0.757
NPC1	O15118-1.2	L104S	Pathogenic	0.835
NPC1	O15118-1.2	L104T	Pathogenic	0.771
NPC1	O15118-1.2	L104V	Pathogenic	0.666
NPC1	O15118-1.2	L104W	Pathogenic	0.875
NPC1	O15118-1.2	L104Y	Pathogenic	0.796
NPC1	O15118-1.2	L105A	Neutral	0.205
NPC1	O15118-1.2	L105C	Neutral	0.223
NPC1	O15118-1.2	L105D	Neutral	0.331
NPC1	O15118-1.2	L105E	Neutral	0.24
NPC1	O15118-1.2	L105F	Neutral	0.17
NPC1	O15118-1.2	L105G	Neutral	0.453
NPC1	O15118-1.2	L105H	Neutral	0.278
NPC1	O15118-1.2	L105I	Neutral	0.081
NPC1	O15118-1.2	L105K	Neutral	0.157
NPC1	O15118-1.2	L105M	Neutral	0.072
NPC1	O15118-1.2	L105N	Neutral	0.257
NPC1	O15118-1.2	L105P	Neutral	0.357
NPC1	O15118-1.2	L105Q	Neutral	0.193
NPC1	O15118-1.2	L105R	Neutral	0.167
NPC1	O15118-1.2	L105S	Neutral	0.246
NPC1	O15118-1.2	L105T	Neutral	0.178
NPC1	O15118-1.2	L105V	Neutral	0.113
NPC1	O15118-1.2	L105W	Neutral	0.31
NPC1	O15118-1.2	L105Y	Neutral	0.201
NPC1	O15118-1.2	N106A	Neutral	0.495
NPC1	O15118-1.2	N106C	Pathogenic	0.507
NPC1	O15118-1.2	N106D	Neutral	0.254
NPC1	O15118-1.2	N106E	Neutral	0.355
NPC1	O15118-1.2	N106F	Neutral	0.484
NPC1	O15118-1.2	N106G	Neutral	0.36
NPC1	O15118-1.2	N106H	Neutral	0.238
NPC1	O15118-1.2	N106I	Neutral	0.466
NPC1	O15118-1.2	N106K	Neutral	0.364
NPC1	O15118-1.2	N106L	Neutral	0.474
NPC1	O15118-1.2	N106M	Neutral	0.417
NPC1	O15118-1.2	N106P	Neutral	0.427
NPC1	O15118-1.2	N106Q	Neutral	0.336
NPC1	O15118-1.2	N106R	Neutral	0.381
NPC1	O15118-1.2	N106S	Neutral	0.25
NPC1	O15118-1.2	N106T	Neutral	0.283
NPC1	O15118-1.2	N106V	Neutral	0.486
NPC1	O15118-1.2	N106W	Pathogenic	0.583
NPC1	O15118-1.2	N106Y	Neutral	0.465
NPC1	O15118-1.2	L107A	Pathogenic	0.568
NPC1	O15118-1.2	L107C	Pathogenic	0.595
NPC1	O15118-1.2	L107D	Pathogenic	0.717
NPC1	O15118-1.2	L107E	Pathogenic	0.617
NPC1	O15118-1.2	L107F	Pathogenic	0.511
NPC1	O15118-1.2	L107G	Pathogenic	0.809
NPC1	O15118-1.2	L107H	Pathogenic	0.663
NPC1	O15118-1.2	L107I	Neutral	0.31
NPC1	O15118-1.2	L107K	Neutral	0.488
NPC1	O15118-1.2	L107M	Neutral	0.285
NPC1	O15118-1.2	L107N	Pathogenic	0.638
NPC1	O15118-1.2	L107P	Pathogenic	0.739
NPC1	O15118-1.2	L107Q	Pathogenic	0.55
NPC1	O15118-1.2	L107R	Pathogenic	0.506
NPC1	O15118-1.2	L107S	Pathogenic	0.625
NPC1	O15118-1.2	L107T	Pathogenic	0.525
NPC1	O15118-1.2	L107V	Neutral	0.395
NPC1	O15118-1.2	L107W	Pathogenic	0.697
NPC1	O15118-1.2	L107Y	Pathogenic	0.562
NPC1	O15118-1.2	F108A	Neutral	0.375
NPC1	O15118-1.2	F108C	Neutral	0.401
NPC1	O15118-1.2	F108D	Neutral	0.348
NPC1	O15118-1.2	F108E	Neutral	0.334
NPC1	O15118-1.2	F108G	Neutral	0.472
NPC1	O15118-1.2	F108H	Neutral	0.221
NPC1	O15118-1.2	F108I	Neutral	0.243
NPC1	O15118-1.2	F108K	Neutral	0.276
NPC1	O15118-1.2	F108L	Neutral	0.238
NPC1	O15118-1.2	F108M	Neutral	0.211
NPC1	O15118-1.2	F108N	Neutral	0.354
NPC1	O15118-1.2	F108P	Pathogenic	0.565
NPC1	O15118-1.2	F108Q	Neutral	0.358
NPC1	O15118-1.2	F108R	Neutral	0.291
NPC1	O15118-1.2	F108S	Neutral	0.341
NPC1	O15118-1.2	F108T	Neutral	0.335
NPC1	O15118-1.2	F108V	Neutral	0.305
NPC1	O15118-1.2	F108W	Neutral	0.172
NPC1	O15118-1.2	F108Y	Neutral	0.069
NPC1	O15118-1.2	C109A	Pathogenic	0.816
NPC1	O15118-1.2	C109D	Pathogenic	0.9
NPC1	O15118-1.2	C109E	Pathogenic	0.939
NPC1	O15118-1.2	C109F	Pathogenic	0.917
NPC1	O15118-1.2	C109G	Pathogenic	0.935
NPC1	O15118-1.2	C109H	Pathogenic	0.935
NPC1	O15118-1.2	C109I	Pathogenic	0.874
NPC1	O15118-1.2	C109K	Pathogenic	0.916
NPC1	O15118-1.2	C109L	Pathogenic	0.878
NPC1	O15118-1.2	C109M	Pathogenic	0.894
NPC1	O15118-1.2	C109N	Pathogenic	0.908
NPC1	O15118-1.2	C109P	Pathogenic	0.937
NPC1	O15118-1.2	C109Q	Pathogenic	0.926
NPC1	O15118-1.2	C109R	Pathogenic	0.922
NPC1	O15118-1.2	C109S	Pathogenic	0.849
NPC1	O15118-1.2	C109T	Pathogenic	0.856
NPC1	O15118-1.2	C109V	Pathogenic	0.883
NPC1	O15118-1.2	C109W	Pathogenic	0.918
NPC1	O15118-1.2	C109Y	Pathogenic	0.937
NPC1	O15118-1.2	E110A	Pathogenic	0.625
NPC1	O15118-1.2	E110C	Pathogenic	0.791
NPC1	O15118-1.2	E110D	Neutral	0.373
NPC1	O15118-1.2	E110F	Pathogenic	0.667
NPC1	O15118-1.2	E110G	Pathogenic	0.753
NPC1	O15118-1.2	E110H	Neutral	0.496
NPC1	O15118-1.2	E110I	Pathogenic	0.651
NPC1	O15118-1.2	E110K	Neutral	0.46
NPC1	O15118-1.2	E110L	Pathogenic	0.658
NPC1	O15118-1.2	E110M	Pathogenic	0.605
NPC1	O15118-1.2	E110N	Pathogenic	0.563
NPC1	O15118-1.2	E110P	Pathogenic	0.559
NPC1	O15118-1.2	E110Q	Neutral	0.333
NPC1	O15118-1.2	E110R	Pathogenic	0.574
NPC1	O15118-1.2	E110S	Pathogenic	0.551
NPC1	O15118-1.2	E110T	Pathogenic	0.592
NPC1	O15118-1.2	E110V	Pathogenic	0.59
NPC1	O15118-1.2	E110W	Pathogenic	0.67
NPC1	O15118-1.2	E110Y	Pathogenic	0.65
NPC1	O15118-1.2	L111A	Neutral	0.443
NPC1	O15118-1.2	L111C	Neutral	0.471
NPC1	O15118-1.2	L111D	Pathogenic	0.605
NPC1	O15118-1.2	L111E	Neutral	0.494
NPC1	O15118-1.2	L111F	Neutral	0.388
NPC1	O15118-1.2	L111G	Pathogenic	0.72
NPC1	O15118-1.2	L111H	Pathogenic	0.544
NPC1	O15118-1.2	L111I	Neutral	0.214
NPC1	O15118-1.2	L111K	Neutral	0.366
NPC1	O15118-1.2	L111M	Neutral	0.194
NPC1	O15118-1.2	L111N	Pathogenic	0.517
NPC1	O15118-1.2	L111P	Pathogenic	0.632
NPC1	O15118-1.2	L111Q	Neutral	0.425
NPC1	O15118-1.2	L111R	Neutral	0.383
NPC1	O15118-1.2	L111S	Pathogenic	0.502
NPC1	O15118-1.2	L111T	Neutral	0.401
NPC1	O15118-1.2	L111V	Neutral	0.284
NPC1	O15118-1.2	L111W	Pathogenic	0.582
NPC1	O15118-1.2	L111Y	Neutral	0.437
NPC1	O15118-1.2	T112A	Pathogenic	0.907
NPC1	O15118-1.2	T112C	Pathogenic	0.911
NPC1	O15118-1.2	T112D	Pathogenic	0.9
NPC1	O15118-1.2	T112E	Pathogenic	0.911
NPC1	O15118-1.2	T112F	Pathogenic	0.934
NPC1	O15118-1.2	T112G	Pathogenic	0.957
NPC1	O15118-1.2	T112H	Pathogenic	0.953
NPC1	O15118-1.2	T112I	Pathogenic	0.9
NPC1	O15118-1.2	T112K	Pathogenic	0.914
NPC1	O15118-1.2	T112L	Pathogenic	0.903
NPC1	O15118-1.2	T112M	Pathogenic	0.916
NPC1	O15118-1.2	T112N	Pathogenic	0.866
NPC1	O15118-1.2	T112P	Pathogenic	0.916
NPC1	O15118-1.2	T112Q	Pathogenic	0.923
NPC1	O15118-1.2	T112R	Pathogenic	0.919
NPC1	O15118-1.2	T112S	Pathogenic	0.855
NPC1	O15118-1.2	T112V	Pathogenic	0.869
NPC1	O15118-1.2	T112W	Pathogenic	0.935
NPC1	O15118-1.2	T112Y	Pathogenic	0.951
NPC1	O15118-1.2	C113A	Pathogenic	0.816
NPC1	O15118-1.2	C113D	Pathogenic	0.9
NPC1	O15118-1.2	C113E	Pathogenic	0.939
NPC1	O15118-1.2	C113F	Pathogenic	0.917
NPC1	O15118-1.2	C113G	Pathogenic	0.935
NPC1	O15118-1.2	C113H	Pathogenic	0.935
NPC1	O15118-1.2	C113I	Pathogenic	0.874
NPC1	O15118-1.2	C113K	Pathogenic	0.916
NPC1	O15118-1.2	C113L	Pathogenic	0.878
NPC1	O15118-1.2	C113M	Pathogenic	0.894
NPC1	O15118-1.2	C113N	Pathogenic	0.908
NPC1	O15118-1.2	C113P	Pathogenic	0.937
NPC1	O15118-1.2	C113Q	Pathogenic	0.926
NPC1	O15118-1.2	C113R	Pathogenic	0.922
NPC1	O15118-1.2	C113S	Pathogenic	0.849
NPC1	O15118-1.2	C113T	Pathogenic	0.856
NPC1	O15118-1.2	C113V	Pathogenic	0.883
NPC1	O15118-1.2	C113W	Pathogenic	0.918
NPC1	O15118-1.2	C113Y	Pathogenic	0.937
NPC1	O15118-1.2	S114A	Pathogenic	0.772
NPC1	O15118-1.2	S114C	Pathogenic	0.86
NPC1	O15118-1.2	S114D	Pathogenic	0.825
NPC1	O15118-1.2	S114E	Pathogenic	0.846
NPC1	O15118-1.2	S114F	Pathogenic	0.903
NPC1	O15118-1.2	S114G	Pathogenic	0.861
NPC1	O15118-1.2	S114H	Pathogenic	0.908
NPC1	O15118-1.2	S114I	Pathogenic	0.896
NPC1	O15118-1.2	S114K	Pathogenic	0.851
NPC1	O15118-1.2	S114L	Pathogenic	0.899
NPC1	O15118-1.2	S114M	Pathogenic	0.876
NPC1	O15118-1.2	S114N	Pathogenic	0.778
NPC1	O15118-1.2	S114P	Pathogenic	0.873
NPC1	O15118-1.2	S114Q	Pathogenic	0.867
NPC1	O15118-1.2	S114R	Pathogenic	0.901
NPC1	O15118-1.2	S114T	Pathogenic	0.79
NPC1	O15118-1.2	S114V	Pathogenic	0.903
NPC1	O15118-1.2	S114W	Pathogenic	0.933
NPC1	O15118-1.2	S114Y	Pathogenic	0.927
NPC1	O15118-1.2	P115A	Pathogenic	0.819
NPC1	O15118-1.2	P115C	Pathogenic	0.901
NPC1	O15118-1.2	P115D	Pathogenic	0.734
NPC1	O15118-1.2	P115E	Pathogenic	0.763
NPC1	O15118-1.2	P115F	Pathogenic	0.929
NPC1	O15118-1.2	P115G	Pathogenic	0.87
NPC1	O15118-1.2	P115H	Pathogenic	0.866
NPC1	O15118-1.2	P115I	Pathogenic	0.893
NPC1	O15118-1.2	P115K	Pathogenic	0.77
NPC1	O15118-1.2	P115L	Pathogenic	0.896
NPC1	O15118-1.2	P115M	Pathogenic	0.873
NPC1	O15118-1.2	P115N	Pathogenic	0.816
NPC1	O15118-1.2	P115Q	Pathogenic	0.792
NPC1	O15118-1.2	P115R	Pathogenic	0.841
NPC1	O15118-1.2	P115S	Pathogenic	0.795
NPC1	O15118-1.2	P115T	Pathogenic	0.797
NPC1	O15118-1.2	P115V	Pathogenic	0.86
NPC1	O15118-1.2	P115W	Pathogenic	0.93
NPC1	O15118-1.2	P115Y	Pathogenic	0.924
NPC1	O15118-1.2	R116A	Neutral	0.316
NPC1	O15118-1.2	R116C	Neutral	0.416
NPC1	O15118-1.2	R116D	Neutral	0.456
NPC1	O15118-1.2	R116E	Neutral	0.25
NPC1	O15118-1.2	R116F	Neutral	0.288
NPC1	O15118-1.2	R116G	Neutral	0.458
NPC1	O15118-1.2	R116H	Neutral	0.196
NPC1	O15118-1.2	R116I	Neutral	0.301
NPC1	O15118-1.2	R116K	Neutral	0.129
NPC1	O15118-1.2	R116L	Neutral	0.232
NPC1	O15118-1.2	R116M	Neutral	0.194
NPC1	O15118-1.2	R116N	Neutral	0.263
NPC1	O15118-1.2	R116P	Neutral	0.34
NPC1	O15118-1.2	R116Q	Neutral	0.161
NPC1	O15118-1.2	R116S	Neutral	0.333
NPC1	O15118-1.2	R116T	Neutral	0.286
NPC1	O15118-1.2	R116V	Neutral	0.37
NPC1	O15118-1.2	R116W	Neutral	0.26
NPC1	O15118-1.2	R116Y	Neutral	0.259
NPC1	O15118-1.2	Q117A	Pathogenic	0.953
NPC1	O15118-1.2	Q117C	Pathogenic	0.969
NPC1	O15118-1.2	Q117D	Pathogenic	0.922
NPC1	O15118-1.2	Q117E	Pathogenic	0.836
NPC1	O15118-1.2	Q117F	Pathogenic	0.958
NPC1	O15118-1.2	Q117G	Pathogenic	0.974
NPC1	O15118-1.2	Q117H	Pathogenic	0.918
NPC1	O15118-1.2	Q117I	Pathogenic	0.955
NPC1	O15118-1.2	Q117K	Pathogenic	0.88
NPC1	O15118-1.2	Q117L	Pathogenic	0.937
NPC1	O15118-1.2	Q117M	Pathogenic	0.889
NPC1	O15118-1.2	Q117N	Pathogenic	0.923
NPC1	O15118-1.2	Q117P	Pathogenic	0.939
NPC1	O15118-1.2	Q117R	Pathogenic	0.888
NPC1	O15118-1.2	Q117S	Pathogenic	0.937
NPC1	O15118-1.2	Q117T	Pathogenic	0.946
NPC1	O15118-1.2	Q117V	Pathogenic	0.946
NPC1	O15118-1.2	Q117W	Pathogenic	0.94
NPC1	O15118-1.2	Q117Y	Pathogenic	0.935
NPC1	O15118-1.2	S118A	Pathogenic	0.74
NPC1	O15118-1.2	S118C	Pathogenic	0.837
NPC1	O15118-1.2	S118D	Pathogenic	0.799
NPC1	O15118-1.2	S118E	Pathogenic	0.822
NPC1	O15118-1.2	S118F	Pathogenic	0.886
NPC1	O15118-1.2	S118G	Pathogenic	0.839
NPC1	O15118-1.2	S118H	Pathogenic	0.892
NPC1	O15118-1.2	S118I	Pathogenic	0.879
NPC1	O15118-1.2	S118K	Pathogenic	0.828
NPC1	O15118-1.2	S118L	Pathogenic	0.882
NPC1	O15118-1.2	S118M	Pathogenic	0.856
NPC1	O15118-1.2	S118N	Pathogenic	0.746
NPC1	O15118-1.2	S118P	Pathogenic	0.852
NPC1	O15118-1.2	S118Q	Pathogenic	0.845
NPC1	O15118-1.2	S118R	Pathogenic	0.884
NPC1	O15118-1.2	S118T	Pathogenic	0.76
NPC1	O15118-1.2	S118V	Pathogenic	0.887
NPC1	O15118-1.2	S118W	Pathogenic	0.921
NPC1	O15118-1.2	S118Y	Pathogenic	0.914
NPC1	O15118-1.2	Q119A	Neutral	0.321
NPC1	O15118-1.2	Q119C	Neutral	0.422
NPC1	O15118-1.2	Q119D	Neutral	0.216
NPC1	O15118-1.2	Q119E	Neutral	0.107
NPC1	O15118-1.2	Q119F	Neutral	0.348
NPC1	O15118-1.2	Q119G	Neutral	0.464
NPC1	O15118-1.2	Q119H	Neutral	0.208
NPC1	O15118-1.2	Q119I	Neutral	0.332
NPC1	O15118-1.2	Q119K	Neutral	0.147
NPC1	O15118-1.2	Q119L	Neutral	0.259
NPC1	O15118-1.2	Q119M	Neutral	0.159
NPC1	O15118-1.2	Q119N	Neutral	0.221
NPC1	O15118-1.2	Q119P	Neutral	0.264
NPC1	O15118-1.2	Q119R	Neutral	0.157
NPC1	O15118-1.2	Q119S	Neutral	0.258
NPC1	O15118-1.2	Q119T	Neutral	0.291
NPC1	O15118-1.2	Q119V	Neutral	0.29
NPC1	O15118-1.2	Q119W	Neutral	0.27
NPC1	O15118-1.2	Q119Y	Neutral	0.252
NPC1	O15118-1.2	F120A	Pathogenic	0.933
NPC1	O15118-1.2	F120C	Pathogenic	0.939
NPC1	O15118-1.2	F120D	Pathogenic	0.925
NPC1	O15118-1.2	F120E	Pathogenic	0.92
NPC1	O15118-1.2	F120G	Pathogenic	0.954
NPC1	O15118-1.2	F120H	Pathogenic	0.867
NPC1	O15118-1.2	F120I	Pathogenic	0.881
NPC1	O15118-1.2	F120K	Pathogenic	0.898
NPC1	O15118-1.2	F120L	Pathogenic	0.878
NPC1	O15118-1.2	F120M	Pathogenic	0.86
NPC1	O15118-1.2	F120N	Pathogenic	0.927
NPC1	O15118-1.2	F120P	Pathogenic	0.968
NPC1	O15118-1.2	F120Q	Pathogenic	0.928
NPC1	O15118-1.2	F120R	Pathogenic	0.904
NPC1	O15118-1.2	F120S	Pathogenic	0.922
NPC1	O15118-1.2	F120T	Pathogenic	0.921
NPC1	O15118-1.2	F120V	Pathogenic	0.91
NPC1	O15118-1.2	F120W	Pathogenic	0.827
NPC1	O15118-1.2	F120Y	Pathogenic	0.632
NPC1	O15118-1.2	L121A	Neutral	0.496
NPC1	O15118-1.2	L121C	Pathogenic	0.524
NPC1	O15118-1.2	L121D	Pathogenic	0.655
NPC1	O15118-1.2	L121E	Pathogenic	0.547
NPC1	O15118-1.2	L121F	Neutral	0.439
NPC1	O15118-1.2	L121G	Pathogenic	0.761
NPC1	O15118-1.2	L121H	Pathogenic	0.596
NPC1	O15118-1.2	L121I	Neutral	0.252
NPC1	O15118-1.2	L121K	Neutral	0.416
NPC1	O15118-1.2	L121M	Neutral	0.23
NPC1	O15118-1.2	L121N	Pathogenic	0.569
NPC1	O15118-1.2	L121P	Pathogenic	0.68
NPC1	O15118-1.2	L121Q	Neutral	0.478
NPC1	O15118-1.2	L121R	Neutral	0.434
NPC1	O15118-1.2	L121S	Pathogenic	0.555
NPC1	O15118-1.2	L121T	Neutral	0.453
NPC1	O15118-1.2	L121V	Neutral	0.329
NPC1	O15118-1.2	L121W	Pathogenic	0.632
NPC1	O15118-1.2	L121Y	Neutral	0.49
NPC1	O15118-1.2	N122A	Neutral	0.404
NPC1	O15118-1.2	N122C	Neutral	0.415
NPC1	O15118-1.2	N122D	Neutral	0.191
NPC1	O15118-1.2	N122E	Neutral	0.275
NPC1	O15118-1.2	N122F	Neutral	0.393
NPC1	O15118-1.2	N122G	Neutral	0.28
NPC1	O15118-1.2	N122H	Neutral	0.178
NPC1	O15118-1.2	N122I	Neutral	0.376
NPC1	O15118-1.2	N122K	Neutral	0.284
NPC1	O15118-1.2	N122L	Neutral	0.384
NPC1	O15118-1.2	N122M	Neutral	0.331
NPC1	O15118-1.2	N122P	Neutral	0.34
NPC1	O15118-1.2	N122Q	Neutral	0.259
NPC1	O15118-1.2	N122R	Neutral	0.299
NPC1	O15118-1.2	N122S	Neutral	0.187
NPC1	O15118-1.2	N122T	Neutral	0.214
NPC1	O15118-1.2	N122V	Neutral	0.395
NPC1	O15118-1.2	N122W	Neutral	0.492
NPC1	O15118-1.2	N122Y	Neutral	0.375
NPC1	O15118-1.2	V123A	Pathogenic	0.583
NPC1	O15118-1.2	V123C	Pathogenic	0.696
NPC1	O15118-1.2	V123D	Pathogenic	0.729
NPC1	O15118-1.2	V123E	Pathogenic	0.642
NPC1	O15118-1.2	V123F	Pathogenic	0.686
NPC1	O15118-1.2	V123G	Pathogenic	0.818
NPC1	O15118-1.2	V123H	Pathogenic	0.783
NPC1	O15118-1.2	V123I	Neutral	0.303
NPC1	O15118-1.2	V123K	Pathogenic	0.651
NPC1	O15118-1.2	V123L	Neutral	0.493
NPC1	O15118-1.2	V123M	Pathogenic	0.532
NPC1	O15118-1.2	V123N	Pathogenic	0.734
NPC1	O15118-1.2	V123P	Pathogenic	0.751
NPC1	O15118-1.2	V123Q	Pathogenic	0.68
NPC1	O15118-1.2	V123R	Pathogenic	0.747
NPC1	O15118-1.2	V123S	Pathogenic	0.722
NPC1	O15118-1.2	V123T	Pathogenic	0.54
NPC1	O15118-1.2	V123W	Pathogenic	0.828
NPC1	O15118-1.2	V123Y	Pathogenic	0.716
NPC1	O15118-1.2	T124A	Pathogenic	0.739
NPC1	O15118-1.2	T124C	Pathogenic	0.748
NPC1	O15118-1.2	T124D	Pathogenic	0.723
NPC1	O15118-1.2	T124E	Pathogenic	0.748
NPC1	O15118-1.2	T124F	Pathogenic	0.805
NPC1	O15118-1.2	T124G	Pathogenic	0.865
NPC1	O15118-1.2	T124H	Pathogenic	0.856
NPC1	O15118-1.2	T124I	Pathogenic	0.723
NPC1	O15118-1.2	T124K	Pathogenic	0.755
NPC1	O15118-1.2	T124L	Pathogenic	0.73
NPC1	O15118-1.2	T124M	Pathogenic	0.76
NPC1	O15118-1.2	T124N	Pathogenic	0.653
NPC1	O15118-1.2	T124P	Pathogenic	0.76
NPC1	O15118-1.2	T124Q	Pathogenic	0.778
NPC1	O15118-1.2	T124R	Pathogenic	0.769
NPC1	O15118-1.2	T124S	Pathogenic	0.631
NPC1	O15118-1.2	T124V	Pathogenic	0.658
NPC1	O15118-1.2	T124W	Pathogenic	0.807
NPC1	O15118-1.2	T124Y	Pathogenic	0.849
NPC1	O15118-1.2	A125C	Neutral	0.15
NPC1	O15118-1.2	A125D	Neutral	0.256
NPC1	O15118-1.2	A125E	Neutral	0.214
NPC1	O15118-1.2	A125F	Neutral	0.282
NPC1	O15118-1.2	A125G	Neutral	0.166
NPC1	O15118-1.2	A125H	Neutral	0.353
NPC1	O15118-1.2	A125I	Neutral	0.199
NPC1	O15118-1.2	A125K	Neutral	0.221
NPC1	O15118-1.2	A125L	Neutral	0.204
NPC1	O15118-1.2	A125M	Neutral	0.231
NPC1	O15118-1.2	A125N	Neutral	0.273
NPC1	O15118-1.2	A125P	Neutral	0.225
NPC1	O15118-1.2	A125Q	Neutral	0.244
NPC1	O15118-1.2	A125R	Neutral	0.234
NPC1	O15118-1.2	A125S	Neutral	0.11
NPC1	O15118-1.2	A125T	Neutral	0.185
NPC1	O15118-1.2	A125V	Neutral	0.155
NPC1	O15118-1.2	A125W	Neutral	0.37
NPC1	O15118-1.2	A125Y	Neutral	0.349
NPC1	O15118-1.2	T126A	Pathogenic	0.517
NPC1	O15118-1.2	T126C	Pathogenic	0.528
NPC1	O15118-1.2	T126D	Neutral	0.496
NPC1	O15118-1.2	T126E	Pathogenic	0.528
NPC1	O15118-1.2	T126F	Pathogenic	0.609
NPC1	O15118-1.2	T126G	Pathogenic	0.708
NPC1	O15118-1.2	T126H	Pathogenic	0.692
NPC1	O15118-1.2	T126I	Neutral	0.497
NPC1	O15118-1.2	T126K	Pathogenic	0.538
NPC1	O15118-1.2	T126L	Pathogenic	0.505
NPC1	O15118-1.2	T126M	Pathogenic	0.544
NPC1	O15118-1.2	T126N	Neutral	0.416
NPC1	O15118-1.2	T126P	Pathogenic	0.544
NPC1	O15118-1.2	T126Q	Pathogenic	0.57
NPC1	O15118-1.2	T126R	Pathogenic	0.556
NPC1	O15118-1.2	T126S	Neutral	0.393
NPC1	O15118-1.2	T126V	Neutral	0.421
NPC1	O15118-1.2	T126W	Pathogenic	0.613
NPC1	O15118-1.2	T126Y	Pathogenic	0.68
NPC1	O15118-1.2	E127A	Neutral	0.184
NPC1	O15118-1.2	E127C	Neutral	0.338
NPC1	O15118-1.2	E127D	Neutral	0.074
NPC1	O15118-1.2	E127F	Neutral	0.213
NPC1	O15118-1.2	E127G	Neutral	0.291
NPC1	O15118-1.2	E127H	Neutral	0.117
NPC1	O15118-1.2	E127I	Neutral	0.201
NPC1	O15118-1.2	E127K	Neutral	0.103
NPC1	O15118-1.2	E127L	Neutral	0.207
NPC1	O15118-1.2	E127M	Neutral	0.171
NPC1	O15118-1.2	E127N	Neutral	0.148
NPC1	O15118-1.2	E127P	Neutral	0.146
NPC1	O15118-1.2	E127Q	Neutral	0.063
NPC1	O15118-1.2	E127R	Neutral	0.154
NPC1	O15118-1.2	E127S	Neutral	0.142
NPC1	O15118-1.2	E127T	Neutral	0.164
NPC1	O15118-1.2	E127V	Neutral	0.163
NPC1	O15118-1.2	E127W	Neutral	0.215
NPC1	O15118-1.2	E127Y	Neutral	0.201
NPC1	O15118-1.2	D128A	Neutral	0.268
NPC1	O15118-1.2	D128C	Neutral	0.277
NPC1	O15118-1.2	D128E	Neutral	0.094
NPC1	O15118-1.2	D128F	Neutral	0.271
NPC1	O15118-1.2	D128G	Neutral	0.236
NPC1	O15118-1.2	D128H	Neutral	0.212
NPC1	O15118-1.2	D128I	Neutral	0.257
NPC1	O15118-1.2	D128K	Neutral	0.272
NPC1	O15118-1.2	D128L	Neutral	0.345
NPC1	O15118-1.2	D128M	Neutral	0.295
NPC1	O15118-1.2	D128N	Neutral	0.122
NPC1	O15118-1.2	D128P	Neutral	0.159
NPC1	O15118-1.2	D128Q	Neutral	0.167
NPC1	O15118-1.2	D128R	Neutral	0.371
NPC1	O15118-1.2	D128S	Neutral	0.155
NPC1	O15118-1.2	D128T	Neutral	0.181
NPC1	O15118-1.2	D128V	Neutral	0.272
NPC1	O15118-1.2	D128W	Neutral	0.357
NPC1	O15118-1.2	D128Y	Neutral	0.336
NPC1	O15118-1.2	Y129A	Pathogenic	0.737
NPC1	O15118-1.2	Y129C	Pathogenic	0.755
NPC1	O15118-1.2	Y129D	Pathogenic	0.714
NPC1	O15118-1.2	Y129E	Pathogenic	0.613
NPC1	O15118-1.2	Y129F	Neutral	0.203
NPC1	O15118-1.2	Y129G	Pathogenic	0.807
NPC1	O15118-1.2	Y129H	Neutral	0.293
NPC1	O15118-1.2	Y129I	Pathogenic	0.559
NPC1	O15118-1.2	Y129K	Pathogenic	0.547
NPC1	O15118-1.2	Y129L	Pathogenic	0.567
NPC1	O15118-1.2	Y129M	Pathogenic	0.605
NPC1	O15118-1.2	Y129N	Pathogenic	0.635
NPC1	O15118-1.2	Y129P	Pathogenic	0.804
NPC1	O15118-1.2	Y129Q	Pathogenic	0.546
NPC1	O15118-1.2	Y129R	Pathogenic	0.547
NPC1	O15118-1.2	Y129S	Pathogenic	0.707
NPC1	O15118-1.2	Y129T	Pathogenic	0.702
NPC1	O15118-1.2	Y129V	Pathogenic	0.633
NPC1	O15118-1.2	Y129W	Neutral	0.261
NPC1	O15118-1.2	V130A	Neutral	0.222
NPC1	O15118-1.2	V130C	Neutral	0.319
NPC1	O15118-1.2	V130D	Neutral	0.355
NPC1	O15118-1.2	V130E	Neutral	0.269
NPC1	O15118-1.2	V130F	Neutral	0.309
NPC1	O15118-1.2	V130G	Neutral	0.479
NPC1	O15118-1.2	V130H	Neutral	0.424
NPC1	O15118-1.2	V130I	Neutral	0.082
NPC1	O15118-1.2	V130K	Neutral	0.277
NPC1	O15118-1.2	V130L	Neutral	0.166
NPC1	O15118-1.2	V130M	Neutral	0.189
NPC1	O15118-1.2	V130N	Neutral	0.36
NPC1	O15118-1.2	V130P	Neutral	0.381
NPC1	O15118-1.2	V130Q	Neutral	0.303
NPC1	O15118-1.2	V130R	Neutral	0.377
NPC1	O15118-1.2	V130S	Neutral	0.347
NPC1	O15118-1.2	V130T	Neutral	0.193
NPC1	O15118-1.2	V130W	Neutral	0.496
NPC1	O15118-1.2	V130Y	Neutral	0.34
NPC1	O15118-1.2	D131A	Pathogenic	0.564
NPC1	O15118-1.2	D131C	Pathogenic	0.576
NPC1	O15118-1.2	D131E	Neutral	0.268
NPC1	O15118-1.2	D131F	Pathogenic	0.568
NPC1	O15118-1.2	D131G	Pathogenic	0.522
NPC1	O15118-1.2	D131H	Neutral	0.487
NPC1	O15118-1.2	D131I	Pathogenic	0.55
NPC1	O15118-1.2	D131K	Pathogenic	0.569
NPC1	O15118-1.2	D131L	Pathogenic	0.65
NPC1	O15118-1.2	D131M	Pathogenic	0.597
NPC1	O15118-1.2	D131N	Neutral	0.329
NPC1	O15118-1.2	D131P	Neutral	0.4
NPC1	O15118-1.2	D131Q	Neutral	0.415
NPC1	O15118-1.2	D131R	Pathogenic	0.677
NPC1	O15118-1.2	D131S	Neutral	0.393
NPC1	O15118-1.2	D131T	Neutral	0.439
NPC1	O15118-1.2	D131V	Pathogenic	0.57
NPC1	O15118-1.2	D131W	Pathogenic	0.662
NPC1	O15118-1.2	D131Y	Pathogenic	0.642
NPC1	O15118-1.2	P132A	Pathogenic	0.72
NPC1	O15118-1.2	P132C	Pathogenic	0.839
NPC1	O15118-1.2	P132D	Pathogenic	0.611
NPC1	O15118-1.2	P132E	Pathogenic	0.647
NPC1	O15118-1.2	P132F	Pathogenic	0.882
NPC1	O15118-1.2	P132G	Pathogenic	0.793
NPC1	O15118-1.2	P132H	Pathogenic	0.786
NPC1	O15118-1.2	P132I	Pathogenic	0.826
NPC1	O15118-1.2	P132K	Pathogenic	0.656
NPC1	O15118-1.2	P132L	Pathogenic	0.831
NPC1	O15118-1.2	P132M	Pathogenic	0.796
NPC1	O15118-1.2	P132N	Pathogenic	0.716
NPC1	O15118-1.2	P132Q	Pathogenic	0.684
NPC1	O15118-1.2	P132R	Pathogenic	0.751
NPC1	O15118-1.2	P132S	Pathogenic	0.688
NPC1	O15118-1.2	P132T	Pathogenic	0.691
NPC1	O15118-1.2	P132V	Pathogenic	0.778
NPC1	O15118-1.2	P132W	Pathogenic	0.884
NPC1	O15118-1.2	P132Y	Pathogenic	0.874
NPC1	O15118-1.2	V133A	Neutral	0.198
NPC1	O15118-1.2	V133C	Neutral	0.289
NPC1	O15118-1.2	V133D	Neutral	0.323
NPC1	O15118-1.2	V133E	Neutral	0.241
NPC1	O15118-1.2	V133F	Neutral	0.28
NPC1	O15118-1.2	V133G	Neutral	0.444
NPC1	O15118-1.2	V133H	Neutral	0.39
NPC1	O15118-1.2	V133I	Neutral	0.072
NPC1	O15118-1.2	V133K	Neutral	0.249
NPC1	O15118-1.2	V133L	Neutral	0.147
NPC1	O15118-1.2	V133M	Neutral	0.168
NPC1	O15118-1.2	V133N	Neutral	0.328
NPC1	O15118-1.2	V133P	Neutral	0.348
NPC1	O15118-1.2	V133Q	Neutral	0.274
NPC1	O15118-1.2	V133R	Neutral	0.344
NPC1	O15118-1.2	V133S	Neutral	0.315
NPC1	O15118-1.2	V133T	Neutral	0.172
NPC1	O15118-1.2	V133W	Neutral	0.46
NPC1	O15118-1.2	V133Y	Neutral	0.309
NPC1	O15118-1.2	T134A	Neutral	0.216
NPC1	O15118-1.2	T134C	Neutral	0.224
NPC1	O15118-1.2	T134D	Neutral	0.202
NPC1	O15118-1.2	T134E	Neutral	0.223
NPC1	O15118-1.2	T134F	Neutral	0.286
NPC1	O15118-1.2	T134G	Neutral	0.384
NPC1	O15118-1.2	T134H	Neutral	0.366
NPC1	O15118-1.2	T134I	Neutral	0.202
NPC1	O15118-1.2	T134K	Neutral	0.231
NPC1	O15118-1.2	T134L	Neutral	0.208
NPC1	O15118-1.2	T134M	Neutral	0.235
NPC1	O15118-1.2	T134N	Neutral	0.155
NPC1	O15118-1.2	T134P	Neutral	0.235
NPC1	O15118-1.2	T134Q	Neutral	0.254
NPC1	O15118-1.2	T134R	Neutral	0.244
NPC1	O15118-1.2	T134S	Neutral	0.143
NPC1	O15118-1.2	T134V	Neutral	0.157
NPC1	O15118-1.2	T134W	Neutral	0.289
NPC1	O15118-1.2	T134Y	Neutral	0.354
NPC1	O15118-1.2	N135A	Neutral	0.105
NPC1	O15118-1.2	N135C	Neutral	0.109
NPC1	O15118-1.2	N135D	Neutral	0.039
NPC1	O15118-1.2	N135E	Neutral	0.062
NPC1	O15118-1.2	N135F	Neutral	0.101
NPC1	O15118-1.2	N135G	Neutral	0.063
NPC1	O15118-1.2	N135H	Neutral	0.036
NPC1	O15118-1.2	N135I	Neutral	0.094
NPC1	O15118-1.2	N135K	Neutral	0.064
NPC1	O15118-1.2	N135L	Neutral	0.097
NPC1	O15118-1.2	N135M	Neutral	0.079
NPC1	O15118-1.2	N135P	Neutral	0.082
NPC1	O15118-1.2	N135Q	Neutral	0.057
NPC1	O15118-1.2	N135R	Neutral	0.069
NPC1	O15118-1.2	N135S	Neutral	0.038
NPC1	O15118-1.2	N135T	Neutral	0.045
NPC1	O15118-1.2	N135V	Neutral	0.101
NPC1	O15118-1.2	N135W	Neutral	0.143
NPC1	O15118-1.2	N135Y	Neutral	0.094
NPC1	O15118-1.2	Q136A	Neutral	0.343
NPC1	O15118-1.2	Q136C	Neutral	0.446
NPC1	O15118-1.2	Q136D	Neutral	0.233
NPC1	O15118-1.2	Q136E	Neutral	0.116
NPC1	O15118-1.2	Q136F	Neutral	0.371
NPC1	O15118-1.2	Q136G	Neutral	0.488
NPC1	O15118-1.2	Q136H	Neutral	0.225
NPC1	O15118-1.2	Q136I	Neutral	0.354
NPC1	O15118-1.2	Q136K	Neutral	0.16
NPC1	O15118-1.2	Q136L	Neutral	0.278
NPC1	O15118-1.2	Q136M	Neutral	0.173
NPC1	O15118-1.2	Q136N	Neutral	0.238
NPC1	O15118-1.2	Q136P	Neutral	0.284
NPC1	O15118-1.2	Q136R	Neutral	0.17
NPC1	O15118-1.2	Q136S	Neutral	0.277
NPC1	O15118-1.2	Q136T	Neutral	0.312
NPC1	O15118-1.2	Q136V	Neutral	0.311
NPC1	O15118-1.2	Q136W	Neutral	0.289
NPC1	O15118-1.2	Q136Y	Neutral	0.271
NPC1	O15118-1.2	T137A	Neutral	0.248
NPC1	O15118-1.2	T137C	Neutral	0.257
NPC1	O15118-1.2	T137D	Neutral	0.233
NPC1	O15118-1.2	T137E	Neutral	0.256
NPC1	O15118-1.2	T137F	Neutral	0.324
NPC1	O15118-1.2	T137G	Neutral	0.428
NPC1	O15118-1.2	T137H	Neutral	0.409
NPC1	O15118-1.2	T137I	Neutral	0.233
NPC1	O15118-1.2	T137K	Neutral	0.264
NPC1	O15118-1.2	T137L	Neutral	0.239
NPC1	O15118-1.2	T137M	Neutral	0.269
NPC1	O15118-1.2	T137N	Neutral	0.18
NPC1	O15118-1.2	T137P	Neutral	0.269
NPC1	O15118-1.2	T137Q	Neutral	0.29
NPC1	O15118-1.2	T137R	Neutral	0.279
NPC1	O15118-1.2	T137S	Neutral	0.166
NPC1	O15118-1.2	T137V	Neutral	0.183
NPC1	O15118-1.2	T137W	Neutral	0.328
NPC1	O15118-1.2	T137Y	Neutral	0.396
NPC1	O15118-1.2	K138A	Neutral	0.478
NPC1	O15118-1.2	K138C	Pathogenic	0.585
NPC1	O15118-1.2	K138D	Pathogenic	0.531
NPC1	O15118-1.2	K138E	Neutral	0.31
NPC1	O15118-1.2	K138F	Neutral	0.445
NPC1	O15118-1.2	K138G	Pathogenic	0.626
NPC1	O15118-1.2	K138H	Neutral	0.416
NPC1	O15118-1.2	K138I	Neutral	0.461
NPC1	O15118-1.2	K138L	Neutral	0.375
NPC1	O15118-1.2	K138M	Neutral	0.323
NPC1	O15118-1.2	K138N	Neutral	0.414
NPC1	O15118-1.2	K138P	Neutral	0.41
NPC1	O15118-1.2	K138Q	Neutral	0.275
NPC1	O15118-1.2	K138R	Neutral	0.24
NPC1	O15118-1.2	K138S	Neutral	0.402
NPC1	O15118-1.2	K138T	Neutral	0.443
NPC1	O15118-1.2	K138V	Neutral	0.442
NPC1	O15118-1.2	K138W	Neutral	0.449
NPC1	O15118-1.2	K138Y	Neutral	0.427
NPC1	O15118-1.2	T139A	Neutral	0.287
NPC1	O15118-1.2	T139C	Neutral	0.297
NPC1	O15118-1.2	T139D	Neutral	0.27
NPC1	O15118-1.2	T139E	Neutral	0.296
NPC1	O15118-1.2	T139F	Neutral	0.369
NPC1	O15118-1.2	T139G	Neutral	0.477
NPC1	O15118-1.2	T139H	Neutral	0.458
NPC1	O15118-1.2	T139I	Neutral	0.271
NPC1	O15118-1.2	T139K	Neutral	0.305
NPC1	O15118-1.2	T139L	Neutral	0.277
NPC1	O15118-1.2	T139M	Neutral	0.31
NPC1	O15118-1.2	T139N	Neutral	0.211
NPC1	O15118-1.2	T139P	Neutral	0.31
NPC1	O15118-1.2	T139Q	Neutral	0.333
NPC1	O15118-1.2	T139R	Neutral	0.32
NPC1	O15118-1.2	T139S	Neutral	0.196
NPC1	O15118-1.2	T139V	Neutral	0.215
NPC1	O15118-1.2	T139W	Neutral	0.373
NPC1	O15118-1.2	T139Y	Neutral	0.445
NPC1	O15118-1.2	N140A	Neutral	0.409
NPC1	O15118-1.2	N140C	Neutral	0.42
NPC1	O15118-1.2	N140D	Neutral	0.194
NPC1	O15118-1.2	N140E	Neutral	0.279
NPC1	O15118-1.2	N140F	Neutral	0.398
NPC1	O15118-1.2	N140G	Neutral	0.284
NPC1	O15118-1.2	N140H	Neutral	0.181
NPC1	O15118-1.2	N140I	Neutral	0.381
NPC1	O15118-1.2	N140K	Neutral	0.287
NPC1	O15118-1.2	N140L	Neutral	0.389
NPC1	O15118-1.2	N140M	Neutral	0.336
NPC1	O15118-1.2	N140P	Neutral	0.344
NPC1	O15118-1.2	N140Q	Neutral	0.263
NPC1	O15118-1.2	N140R	Neutral	0.303
NPC1	O15118-1.2	N140S	Neutral	0.19
NPC1	O15118-1.2	N140T	Neutral	0.217
NPC1	O15118-1.2	N140V	Neutral	0.4
NPC1	O15118-1.2	N140W	Neutral	0.497
NPC1	O15118-1.2	N140Y	Neutral	0.38
NPC1	O15118-1.2	V141A	Pathogenic	0.743
NPC1	O15118-1.2	V141C	Pathogenic	0.826
NPC1	O15118-1.2	V141D	Pathogenic	0.848
NPC1	O15118-1.2	V141E	Pathogenic	0.788
NPC1	O15118-1.2	V141F	Pathogenic	0.82
NPC1	O15118-1.2	V141G	Pathogenic	0.903
NPC1	O15118-1.2	V141H	Pathogenic	0.882
NPC1	O15118-1.2	V141I	Neutral	0.475
NPC1	O15118-1.2	V141K	Pathogenic	0.795
NPC1	O15118-1.2	V141L	Pathogenic	0.669
NPC1	O15118-1.2	V141M	Pathogenic	0.703
NPC1	O15118-1.2	V141N	Pathogenic	0.851
NPC1	O15118-1.2	V141P	Pathogenic	0.862
NPC1	O15118-1.2	V141Q	Pathogenic	0.815
NPC1	O15118-1.2	V141R	Pathogenic	0.86
NPC1	O15118-1.2	V141S	Pathogenic	0.843
NPC1	O15118-1.2	V141T	Pathogenic	0.709
NPC1	O15118-1.2	V141W	Pathogenic	0.909
NPC1	O15118-1.2	V141Y	Pathogenic	0.839
NPC1	O15118-1.2	K142A	Neutral	0.258
NPC1	O15118-1.2	K142C	Neutral	0.348
NPC1	O15118-1.2	K142D	Neutral	0.3
NPC1	O15118-1.2	K142E	Neutral	0.146
NPC1	O15118-1.2	K142F	Neutral	0.233
NPC1	O15118-1.2	K142G	Neutral	0.388
NPC1	O15118-1.2	K142H	Neutral	0.213
NPC1	O15118-1.2	K142I	Neutral	0.244
NPC1	O15118-1.2	K142L	Neutral	0.185
NPC1	O15118-1.2	K142M	Neutral	0.153
NPC1	O15118-1.2	K142N	Neutral	0.211
NPC1	O15118-1.2	K142P	Neutral	0.208
NPC1	O15118-1.2	K142Q	Neutral	0.126
NPC1	O15118-1.2	K142R	Neutral	0.107
NPC1	O15118-1.2	K142S	Neutral	0.203
NPC1	O15118-1.2	K142T	Neutral	0.232
NPC1	O15118-1.2	K142V	Neutral	0.231
NPC1	O15118-1.2	K142W	Neutral	0.236
NPC1	O15118-1.2	K142Y	Neutral	0.22
NPC1	O15118-1.2	E143A	Pathogenic	0.663
NPC1	O15118-1.2	E143C	Pathogenic	0.817
NPC1	O15118-1.2	E143D	Neutral	0.412
NPC1	O15118-1.2	E143F	Pathogenic	0.702
NPC1	O15118-1.2	E143G	Pathogenic	0.782
NPC1	O15118-1.2	E143H	Pathogenic	0.537
NPC1	O15118-1.2	E143I	Pathogenic	0.687
NPC1	O15118-1.2	E143K	Pathogenic	0.501
NPC1	O15118-1.2	E143L	Pathogenic	0.695
NPC1	O15118-1.2	E143M	Pathogenic	0.644
NPC1	O15118-1.2	E143N	Pathogenic	0.603
NPC1	O15118-1.2	E143P	Pathogenic	0.599
NPC1	O15118-1.2	E143Q	Neutral	0.371
NPC1	O15118-1.2	E143R	Pathogenic	0.614
NPC1	O15118-1.2	E143S	Pathogenic	0.591
NPC1	O15118-1.2	E143T	Pathogenic	0.631
NPC1	O15118-1.2	E143V	Pathogenic	0.629
NPC1	O15118-1.2	E143W	Pathogenic	0.706
NPC1	O15118-1.2	E143Y	Pathogenic	0.687
NPC1	O15118-1.2	L144A	Pathogenic	0.591
NPC1	O15118-1.2	L144C	Pathogenic	0.617
NPC1	O15118-1.2	L144D	Pathogenic	0.736
NPC1	O15118-1.2	L144E	Pathogenic	0.639
NPC1	O15118-1.2	L144F	Pathogenic	0.535
NPC1	O15118-1.2	L144G	Pathogenic	0.823
NPC1	O15118-1.2	L144H	Pathogenic	0.684
NPC1	O15118-1.2	L144I	Neutral	0.331
NPC1	O15118-1.2	L144K	Pathogenic	0.511
NPC1	O15118-1.2	L144M	Neutral	0.304
NPC1	O15118-1.2	L144N	Pathogenic	0.66
NPC1	O15118-1.2	L144P	Pathogenic	0.757
NPC1	O15118-1.2	L144Q	Pathogenic	0.573
NPC1	O15118-1.2	L144R	Pathogenic	0.53
NPC1	O15118-1.2	L144S	Pathogenic	0.647
NPC1	O15118-1.2	L144T	Pathogenic	0.549
NPC1	O15118-1.2	L144V	Neutral	0.418
NPC1	O15118-1.2	L144W	Pathogenic	0.716
NPC1	O15118-1.2	L144Y	Pathogenic	0.585
NPC1	O15118-1.2	Q145A	Pathogenic	0.612
NPC1	O15118-1.2	Q145C	Pathogenic	0.708
NPC1	O15118-1.2	Q145D	Neutral	0.479
NPC1	O15118-1.2	Q145E	Neutral	0.285
NPC1	O15118-1.2	Q145F	Pathogenic	0.64
NPC1	O15118-1.2	Q145G	Pathogenic	0.742
NPC1	O15118-1.2	Q145H	Neutral	0.467
NPC1	O15118-1.2	Q145I	Pathogenic	0.624
NPC1	O15118-1.2	Q145K	Neutral	0.365
NPC1	O15118-1.2	Q145L	Pathogenic	0.538
NPC1	O15118-1.2	Q145M	Neutral	0.386
NPC1	O15118-1.2	Q145N	Neutral	0.485
NPC1	O15118-1.2	Q145P	Pathogenic	0.545
NPC1	O15118-1.2	Q145R	Neutral	0.382
NPC1	O15118-1.2	Q145S	Pathogenic	0.537
NPC1	O15118-1.2	Q145T	Pathogenic	0.578
NPC1	O15118-1.2	Q145V	Pathogenic	0.576
NPC1	O15118-1.2	Q145W	Pathogenic	0.551
NPC1	O15118-1.2	Q145Y	Pathogenic	0.529
NPC1	O15118-1.2	Y146A	Pathogenic	0.853
NPC1	O15118-1.2	Y146C	Pathogenic	0.865
NPC1	O15118-1.2	Y146D	Pathogenic	0.838
NPC1	O15118-1.2	Y146E	Pathogenic	0.767
NPC1	O15118-1.2	Y146F	Neutral	0.346
NPC1	O15118-1.2	Y146G	Pathogenic	0.897
NPC1	O15118-1.2	Y146H	Neutral	0.463
NPC1	O15118-1.2	Y146I	Pathogenic	0.725
NPC1	O15118-1.2	Y146K	Pathogenic	0.715
NPC1	O15118-1.2	Y146L	Pathogenic	0.732
NPC1	O15118-1.2	Y146M	Pathogenic	0.761
NPC1	O15118-1.2	Y146N	Pathogenic	0.783
NPC1	O15118-1.2	Y146P	Pathogenic	0.895
NPC1	O15118-1.2	Y146Q	Pathogenic	0.714
NPC1	O15118-1.2	Y146R	Pathogenic	0.715
NPC1	O15118-1.2	Y146S	Pathogenic	0.834
NPC1	O15118-1.2	Y146T	Pathogenic	0.83
NPC1	O15118-1.2	Y146V	Pathogenic	0.782
NPC1	O15118-1.2	Y146W	Neutral	0.424
NPC1	O15118-1.2	Y147A	Pathogenic	0.826
NPC1	O15118-1.2	Y147C	Pathogenic	0.839
NPC1	O15118-1.2	Y147D	Pathogenic	0.808
NPC1	O15118-1.2	Y147E	Pathogenic	0.729
NPC1	O15118-1.2	Y147F	Neutral	0.301
NPC1	O15118-1.2	Y147G	Pathogenic	0.876
NPC1	O15118-1.2	Y147H	Neutral	0.413
NPC1	O15118-1.2	Y147I	Pathogenic	0.682
NPC1	O15118-1.2	Y147K	Pathogenic	0.671
NPC1	O15118-1.2	Y147L	Pathogenic	0.689
NPC1	O15118-1.2	Y147M	Pathogenic	0.722
NPC1	O15118-1.2	Y147N	Pathogenic	0.746
NPC1	O15118-1.2	Y147P	Pathogenic	0.874
NPC1	O15118-1.2	Y147Q	Pathogenic	0.671
NPC1	O15118-1.2	Y147R	Pathogenic	0.672
NPC1	O15118-1.2	Y147S	Pathogenic	0.803
NPC1	O15118-1.2	Y147T	Pathogenic	0.799
NPC1	O15118-1.2	Y147V	Pathogenic	0.745
NPC1	O15118-1.2	Y147W	Neutral	0.375
NPC1	O15118-1.2	V148A	Neutral	0.478
NPC1	O15118-1.2	V148C	Pathogenic	0.601
NPC1	O15118-1.2	V148D	Pathogenic	0.638
NPC1	O15118-1.2	V148E	Pathogenic	0.541
NPC1	O15118-1.2	V148F	Pathogenic	0.59
NPC1	O15118-1.2	V148G	Pathogenic	0.747
NPC1	O15118-1.2	V148H	Pathogenic	0.703
NPC1	O15118-1.2	V148I	Neutral	0.222
NPC1	O15118-1.2	V148K	Pathogenic	0.551
NPC1	O15118-1.2	V148L	Neutral	0.39
NPC1	O15118-1.2	V148M	Neutral	0.428
NPC1	O15118-1.2	V148N	Pathogenic	0.644
NPC1	O15118-1.2	V148P	Pathogenic	0.664
NPC1	O15118-1.2	V148Q	Pathogenic	0.583
NPC1	O15118-1.2	V148R	Pathogenic	0.66
NPC1	O15118-1.2	V148S	Pathogenic	0.63
NPC1	O15118-1.2	V148T	Neutral	0.435
NPC1	O15118-1.2	V148W	Pathogenic	0.76
NPC1	O15118-1.2	V148Y	Pathogenic	0.623
NPC1	O15118-1.2	G149A	Neutral	0.481
NPC1	O15118-1.2	G149C	Pathogenic	0.725
NPC1	O15118-1.2	G149D	Pathogenic	0.574
NPC1	O15118-1.2	G149E	Pathogenic	0.698
NPC1	O15118-1.2	G149F	Pathogenic	0.731
NPC1	O15118-1.2	G149H	Pathogenic	0.743
NPC1	O15118-1.2	G149I	Pathogenic	0.788
NPC1	O15118-1.2	G149K	Pathogenic	0.707
NPC1	O15118-1.2	G149L	Pathogenic	0.794
NPC1	O15118-1.2	G149M	Pathogenic	0.754
NPC1	O15118-1.2	G149N	Pathogenic	0.5
NPC1	O15118-1.2	G149P	Pathogenic	0.667
NPC1	O15118-1.2	G149Q	Pathogenic	0.733
NPC1	O15118-1.2	G149R	Pathogenic	0.722
NPC1	O15118-1.2	G149S	Pathogenic	0.512
NPC1	O15118-1.2	G149T	Pathogenic	0.704
NPC1	O15118-1.2	G149V	Pathogenic	0.733
NPC1	O15118-1.2	G149W	Pathogenic	0.652
NPC1	O15118-1.2	G149Y	Pathogenic	0.788
NPC1	O15118-1.2	Q150A	Neutral	0.298
NPC1	O15118-1.2	Q150C	Neutral	0.396
NPC1	O15118-1.2	Q150D	Neutral	0.199
NPC1	O15118-1.2	Q150E	Neutral	0.097
NPC1	O15118-1.2	Q150F	Neutral	0.325
NPC1	O15118-1.2	Q150G	Neutral	0.437
NPC1	O15118-1.2	Q150H	Neutral	0.191
NPC1	O15118-1.2	Q150I	Neutral	0.309
NPC1	O15118-1.2	Q150K	Neutral	0.134
NPC1	O15118-1.2	Q150L	Neutral	0.239
NPC1	O15118-1.2	Q150M	Neutral	0.145
NPC1	O15118-1.2	Q150N	Neutral	0.203
NPC1	O15118-1.2	Q150P	Neutral	0.244
NPC1	O15118-1.2	Q150R	Neutral	0.143
NPC1	O15118-1.2	Q150S	Neutral	0.238
NPC1	O15118-1.2	Q150T	Neutral	0.27
NPC1	O15118-1.2	Q150V	Neutral	0.269
NPC1	O15118-1.2	Q150W	Neutral	0.249
NPC1	O15118-1.2	Q150Y	Neutral	0.233
NPC1	O15118-1.2	S151A	Neutral	0.115
NPC1	O15118-1.2	S151C	Neutral	0.191
NPC1	O15118-1.2	S151D	Neutral	0.154
NPC1	O15118-1.2	S151E	Neutral	0.175
NPC1	O15118-1.2	S151F	Neutral	0.263
NPC1	O15118-1.2	S151G	Neutral	0.193
NPC1	O15118-1.2	S151H	Neutral	0.275
NPC1	O15118-1.2	S151I	Neutral	0.249
NPC1	O15118-1.2	S151K	Neutral	0.18
NPC1	O15118-1.2	S151L	Neutral	0.256
NPC1	O15118-1.2	S151M	Neutral	0.214
NPC1	O15118-1.2	S151N	Neutral	0.119
NPC1	O15118-1.2	S151P	Neutral	0.208
NPC1	O15118-1.2	S151Q	Neutral	0.2
NPC1	O15118-1.2	S151R	Neutral	0.258
NPC1	O15118-1.2	S151T	Neutral	0.126
NPC1	O15118-1.2	S151V	Neutral	0.264
NPC1	O15118-1.2	S151W	Neutral	0.348
NPC1	O15118-1.2	S151Y	Neutral	0.327
NPC1	O15118-1.2	F152A	Pathogenic	0.871
NPC1	O15118-1.2	F152C	Pathogenic	0.883
NPC1	O15118-1.2	F152D	Pathogenic	0.858
NPC1	O15118-1.2	F152E	Pathogenic	0.849
NPC1	O15118-1.2	F152G	Pathogenic	0.91
NPC1	O15118-1.2	F152H	Pathogenic	0.761
NPC1	O15118-1.2	F152I	Pathogenic	0.783
NPC1	O15118-1.2	F152K	Pathogenic	0.811
NPC1	O15118-1.2	F152L	Pathogenic	0.779
NPC1	O15118-1.2	F152M	Pathogenic	0.751
NPC1	O15118-1.2	F152N	Pathogenic	0.861
NPC1	O15118-1.2	F152P	Pathogenic	0.936
NPC1	O15118-1.2	F152Q	Pathogenic	0.863
NPC1	O15118-1.2	F152R	Pathogenic	0.822
NPC1	O15118-1.2	F152S	Pathogenic	0.853
NPC1	O15118-1.2	F152T	Pathogenic	0.85
NPC1	O15118-1.2	F152V	Pathogenic	0.832
NPC1	O15118-1.2	F152W	Pathogenic	0.701
NPC1	O15118-1.2	F152Y	Neutral	0.456
NPC1	O15118-1.2	A153C	Neutral	0.482
NPC1	O15118-1.2	A153D	Pathogenic	0.645
NPC1	O15118-1.2	A153E	Pathogenic	0.59
NPC1	O15118-1.2	A153F	Pathogenic	0.675
NPC1	O15118-1.2	A153G	Pathogenic	0.513
NPC1	O15118-1.2	A153H	Pathogenic	0.743
NPC1	O15118-1.2	A153I	Pathogenic	0.567
NPC1	O15118-1.2	A153K	Pathogenic	0.6
NPC1	O15118-1.2	A153L	Pathogenic	0.576
NPC1	O15118-1.2	A153M	Pathogenic	0.613
NPC1	O15118-1.2	A153N	Pathogenic	0.664
NPC1	O15118-1.2	A153P	Pathogenic	0.605
NPC1	O15118-1.2	A153Q	Pathogenic	0.63
NPC1	O15118-1.2	A153R	Pathogenic	0.617
NPC1	O15118-1.2	A153S	Neutral	0.395
NPC1	O15118-1.2	A153T	Pathogenic	0.544
NPC1	O15118-1.2	A153V	Neutral	0.491
NPC1	O15118-1.2	A153W	Pathogenic	0.756
NPC1	O15118-1.2	A153Y	Pathogenic	0.739
NPC1	O15118-1.2	N154A	Pathogenic	0.682
NPC1	O15118-1.2	N154C	Pathogenic	0.692
NPC1	O15118-1.2	N154D	Neutral	0.427
NPC1	O15118-1.2	N154E	Pathogenic	0.546
NPC1	O15118-1.2	N154F	Pathogenic	0.672
NPC1	O15118-1.2	N154G	Pathogenic	0.552
NPC1	O15118-1.2	N154H	Neutral	0.406
NPC1	O15118-1.2	N154I	Pathogenic	0.656
NPC1	O15118-1.2	N154K	Pathogenic	0.556
NPC1	O15118-1.2	N154L	Pathogenic	0.663
NPC1	O15118-1.2	N154M	Pathogenic	0.61
NPC1	O15118-1.2	N154P	Pathogenic	0.619
NPC1	O15118-1.2	N154Q	Pathogenic	0.525
NPC1	O15118-1.2	N154R	Pathogenic	0.574
NPC1	O15118-1.2	N154S	Neutral	0.421
NPC1	O15118-1.2	N154T	Neutral	0.462
NPC1	O15118-1.2	N154V	Pathogenic	0.674
NPC1	O15118-1.2	N154W	Pathogenic	0.754
NPC1	O15118-1.2	N154Y	Pathogenic	0.655
NPC1	O15118-1.2	A155C	Neutral	0.416
NPC1	O15118-1.2	A155D	Pathogenic	0.581
NPC1	O15118-1.2	A155E	Pathogenic	0.523
NPC1	O15118-1.2	A155F	Pathogenic	0.613
NPC1	O15118-1.2	A155G	Neutral	0.445
NPC1	O15118-1.2	A155H	Pathogenic	0.688
NPC1	O15118-1.2	A155I	Pathogenic	0.5
NPC1	O15118-1.2	A155K	Pathogenic	0.533
NPC1	O15118-1.2	A155L	Pathogenic	0.509
NPC1	O15118-1.2	A155M	Pathogenic	0.548
NPC1	O15118-1.2	A155N	Pathogenic	0.602
NPC1	O15118-1.2	A155P	Pathogenic	0.539
NPC1	O15118-1.2	A155Q	Pathogenic	0.565
NPC1	O15118-1.2	A155R	Pathogenic	0.552
NPC1	O15118-1.2	A155S	Neutral	0.333
NPC1	O15118-1.2	A155T	Neutral	0.477
NPC1	O15118-1.2	A155V	Neutral	0.425
NPC1	O15118-1.2	A155W	Pathogenic	0.703
NPC1	O15118-1.2	A155Y	Pathogenic	0.684
NPC1	O15118-1.2	M156A	Pathogenic	0.714
NPC1	O15118-1.2	M156C	Pathogenic	0.736
NPC1	O15118-1.2	M156D	Pathogenic	0.766
NPC1	O15118-1.2	M156E	Pathogenic	0.675
NPC1	O15118-1.2	M156F	Pathogenic	0.592
NPC1	O15118-1.2	M156G	Pathogenic	0.846
NPC1	O15118-1.2	M156H	Pathogenic	0.718
NPC1	O15118-1.2	M156I	Neutral	0.479
NPC1	O15118-1.2	M156K	Pathogenic	0.551
NPC1	O15118-1.2	M156L	Neutral	0.393
NPC1	O15118-1.2	M156N	Pathogenic	0.695
NPC1	O15118-1.2	M156P	Pathogenic	0.786
NPC1	O15118-1.2	M156Q	Pathogenic	0.518
NPC1	O15118-1.2	M156R	Pathogenic	0.57
NPC1	O15118-1.2	M156S	Pathogenic	0.682
NPC1	O15118-1.2	M156T	Pathogenic	0.677
NPC1	O15118-1.2	M156V	Pathogenic	0.554
NPC1	O15118-1.2	M156W	Pathogenic	0.685
NPC1	O15118-1.2	M156Y	Pathogenic	0.709
NPC1	O15118-1.2	Y157A	Pathogenic	0.918
NPC1	O15118-1.2	Y157C	Pathogenic	0.925
NPC1	O15118-1.2	Y157D	Pathogenic	0.909
NPC1	O15118-1.2	Y157E	Pathogenic	0.864
NPC1	O15118-1.2	Y157F	Pathogenic	0.505
NPC1	O15118-1.2	Y157G	Pathogenic	0.944
NPC1	O15118-1.2	Y157H	Pathogenic	0.624
NPC1	O15118-1.2	Y157I	Pathogenic	0.835
NPC1	O15118-1.2	Y157K	Pathogenic	0.829
NPC1	O15118-1.2	Y157L	Pathogenic	0.84
NPC1	O15118-1.2	Y157M	Pathogenic	0.86
NPC1	O15118-1.2	Y157N	Pathogenic	0.874
NPC1	O15118-1.2	Y157P	Pathogenic	0.943
NPC1	O15118-1.2	Y157Q	Pathogenic	0.828
NPC1	O15118-1.2	Y157R	Pathogenic	0.829
NPC1	O15118-1.2	Y157S	Pathogenic	0.906
NPC1	O15118-1.2	Y157T	Pathogenic	0.904
NPC1	O15118-1.2	Y157V	Pathogenic	0.874
NPC1	O15118-1.2	Y157W	Pathogenic	0.586
NPC1	O15118-1.2	N158A	Neutral	0.433
NPC1	O15118-1.2	N158C	Neutral	0.445
NPC1	O15118-1.2	N158D	Neutral	0.21
NPC1	O15118-1.2	N158E	Neutral	0.3
NPC1	O15118-1.2	N158F	Neutral	0.422
NPC1	O15118-1.2	N158G	Neutral	0.305
NPC1	O15118-1.2	N158H	Neutral	0.196
NPC1	O15118-1.2	N158I	Neutral	0.405
NPC1	O15118-1.2	N158K	Neutral	0.309
NPC1	O15118-1.2	N158L	Neutral	0.413
NPC1	O15118-1.2	N158M	Neutral	0.359
NPC1	O15118-1.2	N158P	Neutral	0.367
NPC1	O15118-1.2	N158Q	Neutral	0.283
NPC1	O15118-1.2	N158R	Neutral	0.325
NPC1	O15118-1.2	N158S	Neutral	0.206
NPC1	O15118-1.2	N158T	Neutral	0.235
NPC1	O15118-1.2	N158V	Neutral	0.424
NPC1	O15118-1.2	N158W	Pathogenic	0.522
NPC1	O15118-1.2	N158Y	Neutral	0.404
NPC1	O15118-1.2	A159C	Pathogenic	0.762
NPC1	O15118-1.2	A159D	Pathogenic	0.862
NPC1	O15118-1.2	A159E	Pathogenic	0.832
NPC1	O15118-1.2	A159F	Pathogenic	0.877
NPC1	O15118-1.2	A159G	Pathogenic	0.783
NPC1	O15118-1.2	A159H	Pathogenic	0.908
NPC1	O15118-1.2	A159I	Pathogenic	0.819
NPC1	O15118-1.2	A159K	Pathogenic	0.837
NPC1	O15118-1.2	A159L	Pathogenic	0.824
NPC1	O15118-1.2	A159M	Pathogenic	0.845
NPC1	O15118-1.2	A159N	Pathogenic	0.872
NPC1	O15118-1.2	A159P	Pathogenic	0.84
NPC1	O15118-1.2	A159Q	Pathogenic	0.854
NPC1	O15118-1.2	A159R	Pathogenic	0.847
NPC1	O15118-1.2	A159S	Pathogenic	0.692
NPC1	O15118-1.2	A159T	Pathogenic	0.804
NPC1	O15118-1.2	A159V	Pathogenic	0.769
NPC1	O15118-1.2	A159W	Pathogenic	0.914
NPC1	O15118-1.2	A159Y	Pathogenic	0.907
NPC1	O15118-1.2	C160A	Pathogenic	0.817
NPC1	O15118-1.2	C160D	Pathogenic	0.901
NPC1	O15118-1.2	C160E	Pathogenic	0.94
NPC1	O15118-1.2	C160F	Pathogenic	0.917
NPC1	O15118-1.2	C160G	Pathogenic	0.935
NPC1	O15118-1.2	C160H	Pathogenic	0.936
NPC1	O15118-1.2	C160I	Pathogenic	0.875
NPC1	O15118-1.2	C160K	Pathogenic	0.917
NPC1	O15118-1.2	C160L	Pathogenic	0.879
NPC1	O15118-1.2	C160M	Pathogenic	0.895
NPC1	O15118-1.2	C160N	Pathogenic	0.909
NPC1	O15118-1.2	C160P	Pathogenic	0.937
NPC1	O15118-1.2	C160Q	Pathogenic	0.927
NPC1	O15118-1.2	C160R	Pathogenic	0.923
NPC1	O15118-1.2	C160S	Pathogenic	0.85
NPC1	O15118-1.2	C160T	Pathogenic	0.857
NPC1	O15118-1.2	C160V	Pathogenic	0.884
NPC1	O15118-1.2	C160W	Pathogenic	0.919
NPC1	O15118-1.2	C160Y	Pathogenic	0.937
NPC1	O15118-1.2	R161A	Pathogenic	0.507
NPC1	O15118-1.2	R161C	Pathogenic	0.613
NPC1	O15118-1.2	R161D	Pathogenic	0.652
NPC1	O15118-1.2	R161E	Neutral	0.426
NPC1	O15118-1.2	R161F	Neutral	0.474
NPC1	O15118-1.2	R161G	Pathogenic	0.653
NPC1	O15118-1.2	R161H	Neutral	0.353
NPC1	O15118-1.2	R161I	Neutral	0.489
NPC1	O15118-1.2	R161K	Neutral	0.248
NPC1	O15118-1.2	R161L	Neutral	0.403
NPC1	O15118-1.2	R161M	Neutral	0.349
NPC1	O15118-1.2	R161N	Neutral	0.442
NPC1	O15118-1.2	R161P	Pathogenic	0.534
NPC1	O15118-1.2	R161Q	Neutral	0.299
NPC1	O15118-1.2	R161S	Pathogenic	0.527
NPC1	O15118-1.2	R161T	Neutral	0.472
NPC1	O15118-1.2	R161V	Pathogenic	0.567
NPC1	O15118-1.2	R161W	Neutral	0.439
NPC1	O15118-1.2	R161Y	Neutral	0.438
NPC1	O15118-1.2	D162A	Pathogenic	0.535
NPC1	O15118-1.2	D162C	Pathogenic	0.546
NPC1	O15118-1.2	D162E	Neutral	0.245
NPC1	O15118-1.2	D162F	Pathogenic	0.538
NPC1	O15118-1.2	D162G	Neutral	0.493
NPC1	O15118-1.2	D162H	Neutral	0.458
NPC1	O15118-1.2	D162I	Pathogenic	0.521
NPC1	O15118-1.2	D162K	Pathogenic	0.54
NPC1	O15118-1.2	D162L	Pathogenic	0.623
NPC1	O15118-1.2	D162M	Pathogenic	0.568
NPC1	O15118-1.2	D162N	Neutral	0.303
NPC1	O15118-1.2	D162P	Neutral	0.372
NPC1	O15118-1.2	D162Q	Neutral	0.386
NPC1	O15118-1.2	D162R	Pathogenic	0.65
NPC1	O15118-1.2	D162S	Neutral	0.365
NPC1	O15118-1.2	D162T	Neutral	0.41
NPC1	O15118-1.2	D162V	Pathogenic	0.54
NPC1	O15118-1.2	D162W	Pathogenic	0.635
NPC1	O15118-1.2	D162Y	Pathogenic	0.614
NPC1	O15118-1.2	V163A	Pathogenic	0.918
NPC1	O15118-1.2	V163C	Pathogenic	0.948
NPC1	O15118-1.2	V163D	Pathogenic	0.956
NPC1	O15118-1.2	V163E	Pathogenic	0.935
NPC1	O15118-1.2	V163F	Pathogenic	0.946
NPC1	O15118-1.2	V163G	Pathogenic	0.973
NPC1	O15118-1.2	V163H	Pathogenic	0.967
NPC1	O15118-1.2	V163I	Pathogenic	0.778
NPC1	O15118-1.2	V163K	Pathogenic	0.938
NPC1	O15118-1.2	V163L	Pathogenic	0.887
NPC1	O15118-1.2	V163M	Pathogenic	0.901
NPC1	O15118-1.2	V163N	Pathogenic	0.957
NPC1	O15118-1.2	V163P	Pathogenic	0.96
NPC1	O15118-1.2	V163Q	Pathogenic	0.945
NPC1	O15118-1.2	V163R	Pathogenic	0.96
NPC1	O15118-1.2	V163S	Pathogenic	0.954
NPC1	O15118-1.2	V163T	Pathogenic	0.904
NPC1	O15118-1.2	V163W	Pathogenic	0.975
NPC1	O15118-1.2	V163Y	Pathogenic	0.953
NPC1	O15118-1.2	E164A	Neutral	0.425
NPC1	O15118-1.2	E164C	Pathogenic	0.626
NPC1	O15118-1.2	E164D	Neutral	0.208
NPC1	O15118-1.2	E164F	Neutral	0.47
NPC1	O15118-1.2	E164G	Pathogenic	0.575
NPC1	O15118-1.2	E164H	Neutral	0.304
NPC1	O15118-1.2	E164I	Neutral	0.452
NPC1	O15118-1.2	E164K	Neutral	0.274
NPC1	O15118-1.2	E164L	Neutral	0.461
NPC1	O15118-1.2	E164M	Neutral	0.405
NPC1	O15118-1.2	E164N	Neutral	0.363
NPC1	O15118-1.2	E164P	Neutral	0.36
NPC1	O15118-1.2	E164Q	Neutral	0.181
NPC1	O15118-1.2	E164R	Neutral	0.374
NPC1	O15118-1.2	E164S	Neutral	0.352
NPC1	O15118-1.2	E164T	Neutral	0.391
NPC1	O15118-1.2	E164V	Neutral	0.39
NPC1	O15118-1.2	E164W	Neutral	0.474
NPC1	O15118-1.2	E164Y	Neutral	0.452
NPC1	O15118-1.2	A165C	Neutral	0.312
NPC1	O15118-1.2	A165D	Neutral	0.469
NPC1	O15118-1.2	A165E	Neutral	0.412
NPC1	O15118-1.2	A165F	Pathogenic	0.502
NPC1	O15118-1.2	A165G	Neutral	0.339
NPC1	O15118-1.2	A165H	Pathogenic	0.584
NPC1	O15118-1.2	A165I	Neutral	0.39
NPC1	O15118-1.2	A165K	Neutral	0.422
NPC1	O15118-1.2	A165L	Neutral	0.398
NPC1	O15118-1.2	A165M	Neutral	0.436
NPC1	O15118-1.2	A165N	Neutral	0.491
NPC1	O15118-1.2	A165P	Neutral	0.427
NPC1	O15118-1.2	A165Q	Neutral	0.453
NPC1	O15118-1.2	A165R	Neutral	0.44
NPC1	O15118-1.2	A165S	Neutral	0.241
NPC1	O15118-1.2	A165T	Neutral	0.368
NPC1	O15118-1.2	A165V	Neutral	0.32
NPC1	O15118-1.2	A165W	Pathogenic	0.601
NPC1	O15118-1.2	A165Y	Pathogenic	0.579
NPC1	O15118-1.2	P166A	Pathogenic	0.95
NPC1	O15118-1.2	P166C	Pathogenic	0.975
NPC1	O15118-1.2	P166D	Pathogenic	0.921
NPC1	O15118-1.2	P166E	Pathogenic	0.932
NPC1	O15118-1.2	P166F	Pathogenic	0.982
NPC1	O15118-1.2	P166G	Pathogenic	0.966
NPC1	O15118-1.2	P166H	Pathogenic	0.965
NPC1	O15118-1.2	P166I	Pathogenic	0.972
NPC1	O15118-1.2	P166K	Pathogenic	0.934
NPC1	O15118-1.2	P166L	Pathogenic	0.973
NPC1	O15118-1.2	P166M	Pathogenic	0.967
NPC1	O15118-1.2	P166N	Pathogenic	0.949
NPC1	O15118-1.2	P166Q	Pathogenic	0.942
NPC1	O15118-1.2	P166R	Pathogenic	0.957
NPC1	O15118-1.2	P166S	Pathogenic	0.943
NPC1	O15118-1.2	P166T	Pathogenic	0.943
NPC1	O15118-1.2	P166V	Pathogenic	0.963
NPC1	O15118-1.2	P166W	Pathogenic	0.983
NPC1	O15118-1.2	P166Y	Pathogenic	0.981
NPC1	O15118-1.2	S167A	Pathogenic	0.643
NPC1	O15118-1.2	S167C	Pathogenic	0.765
NPC1	O15118-1.2	S167D	Pathogenic	0.715
NPC1	O15118-1.2	S167E	Pathogenic	0.745
NPC1	O15118-1.2	S167F	Pathogenic	0.831
NPC1	O15118-1.2	S167G	Pathogenic	0.767
NPC1	O15118-1.2	S167H	Pathogenic	0.84
NPC1	O15118-1.2	S167I	Pathogenic	0.821
NPC1	O15118-1.2	S167K	Pathogenic	0.753
NPC1	O15118-1.2	S167L	Pathogenic	0.826
NPC1	O15118-1.2	S167M	Pathogenic	0.79
NPC1	O15118-1.2	S167N	Pathogenic	0.65
NPC1	O15118-1.2	S167P	Pathogenic	0.785
NPC1	O15118-1.2	S167Q	Pathogenic	0.776
NPC1	O15118-1.2	S167R	Pathogenic	0.828
NPC1	O15118-1.2	S167T	Pathogenic	0.666
NPC1	O15118-1.2	S167V	Pathogenic	0.832
NPC1	O15118-1.2	S167W	Pathogenic	0.88
NPC1	O15118-1.2	S167Y	Pathogenic	0.871
NPC1	O15118-1.2	S168A	Neutral	0.469
NPC1	O15118-1.2	S168C	Pathogenic	0.614
NPC1	O15118-1.2	S168D	Pathogenic	0.551
NPC1	O15118-1.2	S168E	Pathogenic	0.589
NPC1	O15118-1.2	S168F	Pathogenic	0.707
NPC1	O15118-1.2	S168G	Pathogenic	0.618
NPC1	O15118-1.2	S168H	Pathogenic	0.72
NPC1	O15118-1.2	S168I	Pathogenic	0.692
NPC1	O15118-1.2	S168K	Pathogenic	0.598
NPC1	O15118-1.2	S168L	Pathogenic	0.699
NPC1	O15118-1.2	S168M	Pathogenic	0.649
NPC1	O15118-1.2	S168N	Neutral	0.477
NPC1	O15118-1.2	S168P	Pathogenic	0.641
NPC1	O15118-1.2	S168Q	Pathogenic	0.629
NPC1	O15118-1.2	S168R	Pathogenic	0.702
NPC1	O15118-1.2	S168T	Neutral	0.494
NPC1	O15118-1.2	S168V	Pathogenic	0.709
NPC1	O15118-1.2	S168W	Pathogenic	0.783
NPC1	O15118-1.2	S168Y	Pathogenic	0.767
NPC1	O15118-1.2	N169A	Pathogenic	0.865
NPC1	O15118-1.2	N169C	Pathogenic	0.871
NPC1	O15118-1.2	N169D	Pathogenic	0.691
NPC1	O15118-1.2	N169E	Pathogenic	0.783
NPC1	O15118-1.2	N169F	Pathogenic	0.86
NPC1	O15118-1.2	N169G	Pathogenic	0.787
NPC1	O15118-1.2	N169H	Pathogenic	0.672
NPC1	O15118-1.2	N169I	Pathogenic	0.851
NPC1	O15118-1.2	N169K	Pathogenic	0.79
NPC1	O15118-1.2	N169L	Pathogenic	0.855
NPC1	O15118-1.2	N169M	Pathogenic	0.825
NPC1	O15118-1.2	N169P	Pathogenic	0.83
NPC1	O15118-1.2	N169Q	Pathogenic	0.768
NPC1	O15118-1.2	N169R	Pathogenic	0.802
NPC1	O15118-1.2	N169S	Pathogenic	0.686
NPC1	O15118-1.2	N169T	Pathogenic	0.721
NPC1	O15118-1.2	N169V	Pathogenic	0.861
NPC1	O15118-1.2	N169W	Pathogenic	0.902
NPC1	O15118-1.2	N169Y	Pathogenic	0.851
NPC1	O15118-1.2	D170A	Neutral	0.283
NPC1	O15118-1.2	D170C	Neutral	0.293
NPC1	O15118-1.2	D170E	Neutral	0.1
NPC1	O15118-1.2	D170F	Neutral	0.286
NPC1	O15118-1.2	D170G	Neutral	0.25
NPC1	O15118-1.2	D170H	Neutral	0.225
NPC1	O15118-1.2	D170I	Neutral	0.272
NPC1	O15118-1.2	D170K	Neutral	0.287
NPC1	O15118-1.2	D170L	Neutral	0.362
NPC1	O15118-1.2	D170M	Neutral	0.311
NPC1	O15118-1.2	D170N	Neutral	0.13
NPC1	O15118-1.2	D170P	Neutral	0.169
NPC1	O15118-1.2	D170Q	Neutral	0.178
NPC1	O15118-1.2	D170R	Neutral	0.39
NPC1	O15118-1.2	D170S	Neutral	0.165
NPC1	O15118-1.2	D170T	Neutral	0.193
NPC1	O15118-1.2	D170V	Neutral	0.288
NPC1	O15118-1.2	D170W	Neutral	0.375
NPC1	O15118-1.2	D170Y	Neutral	0.354
NPC1	O15118-1.2	K171A	Pathogenic	0.671
NPC1	O15118-1.2	K171C	Pathogenic	0.759
NPC1	O15118-1.2	K171D	Pathogenic	0.716
NPC1	O15118-1.2	K171E	Pathogenic	0.5
NPC1	O15118-1.2	K171F	Pathogenic	0.641
NPC1	O15118-1.2	K171G	Pathogenic	0.788
NPC1	O15118-1.2	K171H	Pathogenic	0.613
NPC1	O15118-1.2	K171I	Pathogenic	0.655
NPC1	O15118-1.2	K171L	Pathogenic	0.572
NPC1	O15118-1.2	K171M	Pathogenic	0.515
NPC1	O15118-1.2	K171N	Pathogenic	0.611
NPC1	O15118-1.2	K171P	Pathogenic	0.607
NPC1	O15118-1.2	K171Q	Neutral	0.458
NPC1	O15118-1.2	K171R	Neutral	0.413
NPC1	O15118-1.2	K171S	Pathogenic	0.6
NPC1	O15118-1.2	K171T	Pathogenic	0.639
NPC1	O15118-1.2	K171V	Pathogenic	0.638
NPC1	O15118-1.2	K171W	Pathogenic	0.645
NPC1	O15118-1.2	K171Y	Pathogenic	0.624
NPC1	O15118-1.2	A172C	Pathogenic	0.854
NPC1	O15118-1.2	A172D	Pathogenic	0.919
NPC1	O15118-1.2	A172E	Pathogenic	0.9
NPC1	O15118-1.2	A172F	Pathogenic	0.928
NPC1	O15118-1.2	A172G	Pathogenic	0.868
NPC1	O15118-1.2	A172H	Pathogenic	0.948
NPC1	O15118-1.2	A172I	Pathogenic	0.891
NPC1	O15118-1.2	A172K	Pathogenic	0.904
NPC1	O15118-1.2	A172L	Pathogenic	0.895
NPC1	O15118-1.2	A172M	Pathogenic	0.908
NPC1	O15118-1.2	A172N	Pathogenic	0.925
NPC1	O15118-1.2	A172P	Pathogenic	0.906
NPC1	O15118-1.2	A172Q	Pathogenic	0.914
NPC1	O15118-1.2	A172R	Pathogenic	0.91
NPC1	O15118-1.2	A172S	Pathogenic	0.803
NPC1	O15118-1.2	A172T	Pathogenic	0.882
NPC1	O15118-1.2	A172V	Pathogenic	0.858
NPC1	O15118-1.2	A172W	Pathogenic	0.951
NPC1	O15118-1.2	A172Y	Pathogenic	0.947
NPC1	O15118-1.2	L173A	Pathogenic	0.735
NPC1	O15118-1.2	L173C	Pathogenic	0.755
NPC1	O15118-1.2	L173D	Pathogenic	0.842
NPC1	O15118-1.2	L173E	Pathogenic	0.772
NPC1	O15118-1.2	L173F	Pathogenic	0.687
NPC1	O15118-1.2	L173G	Pathogenic	0.899
NPC1	O15118-1.2	L173H	Pathogenic	0.806
NPC1	O15118-1.2	L173I	Neutral	0.486
NPC1	O15118-1.2	L173K	Pathogenic	0.667
NPC1	O15118-1.2	L173M	Neutral	0.456
NPC1	O15118-1.2	L173N	Pathogenic	0.788
NPC1	O15118-1.2	L173P	Pathogenic	0.857
NPC1	O15118-1.2	L173Q	Pathogenic	0.72
NPC1	O15118-1.2	L173R	Pathogenic	0.683
NPC1	O15118-1.2	L173S	Pathogenic	0.778
NPC1	O15118-1.2	L173T	Pathogenic	0.699
NPC1	O15118-1.2	L173V	Pathogenic	0.579
NPC1	O15118-1.2	L173W	Pathogenic	0.829
NPC1	O15118-1.2	L173Y	Pathogenic	0.73
NPC1	O15118-1.2	G174A	Neutral	0.427
NPC1	O15118-1.2	G174C	Pathogenic	0.68
NPC1	O15118-1.2	G174D	Pathogenic	0.521
NPC1	O15118-1.2	G174E	Pathogenic	0.651
NPC1	O15118-1.2	G174F	Pathogenic	0.686
NPC1	O15118-1.2	G174H	Pathogenic	0.7
NPC1	O15118-1.2	G174I	Pathogenic	0.75
NPC1	O15118-1.2	G174K	Pathogenic	0.66
NPC1	O15118-1.2	G174L	Pathogenic	0.756
NPC1	O15118-1.2	G174M	Pathogenic	0.711
NPC1	O15118-1.2	G174N	Neutral	0.446
NPC1	O15118-1.2	G174P	Pathogenic	0.618
NPC1	O15118-1.2	G174Q	Pathogenic	0.688
NPC1	O15118-1.2	G174R	Pathogenic	0.676
NPC1	O15118-1.2	G174S	Neutral	0.458
NPC1	O15118-1.2	G174T	Pathogenic	0.658
NPC1	O15118-1.2	G174V	Pathogenic	0.688
NPC1	O15118-1.2	G174W	Pathogenic	0.602
NPC1	O15118-1.2	G174Y	Pathogenic	0.749
NPC1	O15118-1.2	L175A	Neutral	0.405
NPC1	O15118-1.2	L175C	Neutral	0.432
NPC1	O15118-1.2	L175D	Pathogenic	0.567
NPC1	O15118-1.2	L175E	Neutral	0.455
NPC1	O15118-1.2	L175F	Neutral	0.351
NPC1	O15118-1.2	L175G	Pathogenic	0.687
NPC1	O15118-1.2	L175H	Pathogenic	0.505
NPC1	O15118-1.2	L175I	Neutral	0.189
NPC1	O15118-1.2	L175K	Neutral	0.33
NPC1	O15118-1.2	L175M	Neutral	0.171
NPC1	O15118-1.2	L175N	Neutral	0.478
NPC1	O15118-1.2	L175P	Pathogenic	0.595
NPC1	O15118-1.2	L175Q	Neutral	0.388
NPC1	O15118-1.2	L175R	Neutral	0.347
NPC1	O15118-1.2	L175S	Neutral	0.463
NPC1	O15118-1.2	L175T	Neutral	0.364
NPC1	O15118-1.2	L175V	Neutral	0.253
NPC1	O15118-1.2	L175W	Pathogenic	0.543
NPC1	O15118-1.2	L175Y	Neutral	0.399
NPC1	O15118-1.2	L176A	Neutral	0.399
NPC1	O15118-1.2	L176C	Neutral	0.425
NPC1	O15118-1.2	L176D	Pathogenic	0.56
NPC1	O15118-1.2	L176E	Neutral	0.448
NPC1	O15118-1.2	L176F	Neutral	0.345
NPC1	O15118-1.2	L176G	Pathogenic	0.681
NPC1	O15118-1.2	L176H	Neutral	0.498
NPC1	O15118-1.2	L176I	Neutral	0.185
NPC1	O15118-1.2	L176K	Neutral	0.324
NPC1	O15118-1.2	L176M	Neutral	0.167
NPC1	O15118-1.2	L176N	Neutral	0.471
NPC1	O15118-1.2	L176P	Pathogenic	0.588
NPC1	O15118-1.2	L176Q	Neutral	0.381
NPC1	O15118-1.2	L176R	Neutral	0.34
NPC1	O15118-1.2	L176S	Neutral	0.456
NPC1	O15118-1.2	L176T	Neutral	0.358
NPC1	O15118-1.2	L176V	Neutral	0.248
NPC1	O15118-1.2	L176W	Pathogenic	0.536
NPC1	O15118-1.2	L176Y	Neutral	0.393
NPC1	O15118-1.2	C177A	Pathogenic	0.815
NPC1	O15118-1.2	C177D	Pathogenic	0.9
NPC1	O15118-1.2	C177E	Pathogenic	0.939
NPC1	O15118-1.2	C177F	Pathogenic	0.916
NPC1	O15118-1.2	C177G	Pathogenic	0.934
NPC1	O15118-1.2	C177H	Pathogenic	0.935
NPC1	O15118-1.2	C177I	Pathogenic	0.874
NPC1	O15118-1.2	C177K	Pathogenic	0.916
NPC1	O15118-1.2	C177L	Pathogenic	0.878
NPC1	O15118-1.2	C177M	Pathogenic	0.893
NPC1	O15118-1.2	C177N	Pathogenic	0.908
NPC1	O15118-1.2	C177P	Pathogenic	0.936
NPC1	O15118-1.2	C177Q	Pathogenic	0.926
NPC1	O15118-1.2	C177R	Pathogenic	0.922
NPC1	O15118-1.2	C177S	Pathogenic	0.848
NPC1	O15118-1.2	C177T	Pathogenic	0.856
NPC1	O15118-1.2	C177V	Pathogenic	0.882
NPC1	O15118-1.2	C177W	Pathogenic	0.918
NPC1	O15118-1.2	C177Y	Pathogenic	0.936
NPC1	O15118-1.2	G178A	Pathogenic	0.769
NPC1	O15118-1.2	G178C	Pathogenic	0.905
NPC1	O15118-1.2	G178D	Pathogenic	0.829
NPC1	O15118-1.2	G178E	Pathogenic	0.893
NPC1	O15118-1.2	G178F	Pathogenic	0.907
NPC1	O15118-1.2	G178H	Pathogenic	0.912
NPC1	O15118-1.2	G178I	Pathogenic	0.93
NPC1	O15118-1.2	G178K	Pathogenic	0.896
NPC1	O15118-1.2	G178L	Pathogenic	0.932
NPC1	O15118-1.2	G178M	Pathogenic	0.917
NPC1	O15118-1.2	G178N	Pathogenic	0.782
NPC1	O15118-1.2	G178P	Pathogenic	0.878
NPC1	O15118-1.2	G178Q	Pathogenic	0.908
NPC1	O15118-1.2	G178R	Pathogenic	0.903
NPC1	O15118-1.2	G178S	Pathogenic	0.79
NPC1	O15118-1.2	G178T	Pathogenic	0.895
NPC1	O15118-1.2	G178V	Pathogenic	0.908
NPC1	O15118-1.2	G178W	Pathogenic	0.871
NPC1	O15118-1.2	G178Y	Pathogenic	0.93
NPC1	O15118-1.2	K179A	Neutral	0.103
NPC1	O15118-1.2	K179C	Neutral	0.15
NPC1	O15118-1.2	K179D	Neutral	0.125
NPC1	O15118-1.2	K179E	Neutral	0.053
NPC1	O15118-1.2	K179F	Neutral	0.092
NPC1	O15118-1.2	K179G	Neutral	0.174
NPC1	O15118-1.2	K179H	Neutral	0.082
NPC1	O15118-1.2	K179I	Neutral	0.097
NPC1	O15118-1.2	K179L	Neutral	0.07
NPC1	O15118-1.2	K179M	Neutral	0.057
NPC1	O15118-1.2	K179N	Neutral	0.081
NPC1	O15118-1.2	K179P	Neutral	0.08
NPC1	O15118-1.2	K179Q	Neutral	0.045
NPC1	O15118-1.2	K179R	Neutral	0.038
NPC1	O15118-1.2	K179S	Neutral	0.078
NPC1	O15118-1.2	K179T	Neutral	0.091
NPC1	O15118-1.2	K179V	Neutral	0.09
NPC1	O15118-1.2	K179W	Neutral	0.093
NPC1	O15118-1.2	K179Y	Neutral	0.086
NPC1	O15118-1.2	D180A	Neutral	0.191
NPC1	O15118-1.2	D180C	Neutral	0.198
NPC1	O15118-1.2	D180E	Neutral	0.062
NPC1	O15118-1.2	D180F	Neutral	0.193
NPC1	O15118-1.2	D180G	Neutral	0.166
NPC1	O15118-1.2	D180H	Neutral	0.147
NPC1	O15118-1.2	D180I	Neutral	0.182
NPC1	O15118-1.2	D180K	Neutral	0.194
NPC1	O15118-1.2	D180L	Neutral	0.253
NPC1	O15118-1.2	D180M	Neutral	0.212
NPC1	O15118-1.2	D180N	Neutral	0.082
NPC1	O15118-1.2	D180P	Neutral	0.108
NPC1	O15118-1.2	D180Q	Neutral	0.114
NPC1	O15118-1.2	D180R	Neutral	0.276
NPC1	O15118-1.2	D180S	Neutral	0.105
NPC1	O15118-1.2	D180T	Neutral	0.125
NPC1	O15118-1.2	D180V	Neutral	0.194
NPC1	O15118-1.2	D180W	Neutral	0.263
NPC1	O15118-1.2	D180Y	Neutral	0.246
NPC1	O15118-1.2	A181C	Neutral	0.151
NPC1	O15118-1.2	A181D	Neutral	0.257
NPC1	O15118-1.2	A181E	Neutral	0.215
NPC1	O15118-1.2	A181F	Neutral	0.283
NPC1	O15118-1.2	A181G	Neutral	0.167
NPC1	O15118-1.2	A181H	Neutral	0.355
NPC1	O15118-1.2	A181I	Neutral	0.2
NPC1	O15118-1.2	A181K	Neutral	0.222
NPC1	O15118-1.2	A181L	Neutral	0.205
NPC1	O15118-1.2	A181M	Neutral	0.232
NPC1	O15118-1.2	A181N	Neutral	0.274
NPC1	O15118-1.2	A181P	Neutral	0.226
NPC1	O15118-1.2	A181Q	Neutral	0.245
NPC1	O15118-1.2	A181R	Neutral	0.235
NPC1	O15118-1.2	A181S	Neutral	0.111
NPC1	O15118-1.2	A181T	Neutral	0.185
NPC1	O15118-1.2	A181V	Neutral	0.155
NPC1	O15118-1.2	A181W	Neutral	0.371
NPC1	O15118-1.2	A181Y	Neutral	0.35
NPC1	O15118-1.2	D182A	Neutral	0.112
NPC1	O15118-1.2	D182C	Neutral	0.116
NPC1	O15118-1.2	D182E	Neutral	0.034
NPC1	O15118-1.2	D182F	Neutral	0.113
NPC1	O15118-1.2	D182G	Neutral	0.096
NPC1	O15118-1.2	D182H	Neutral	0.084
NPC1	O15118-1.2	D182I	Neutral	0.106
NPC1	O15118-1.2	D182K	Neutral	0.114
NPC1	O15118-1.2	D182L	Neutral	0.153
NPC1	O15118-1.2	D182M	Neutral	0.125
NPC1	O15118-1.2	D182N	Neutral	0.045
NPC1	O15118-1.2	D182P	Neutral	0.061
NPC1	O15118-1.2	D182Q	Neutral	0.064
NPC1	O15118-1.2	D182R	Neutral	0.169
NPC1	O15118-1.2	D182S	Neutral	0.059
NPC1	O15118-1.2	D182T	Neutral	0.071
NPC1	O15118-1.2	D182V	Neutral	0.114
NPC1	O15118-1.2	D182W	Neutral	0.16
NPC1	O15118-1.2	D182Y	Neutral	0.148
NPC1	O15118-1.2	A183C	Neutral	0.069
NPC1	O15118-1.2	A183D	Neutral	0.125
NPC1	O15118-1.2	A183E	Neutral	0.102
NPC1	O15118-1.2	A183F	Neutral	0.141
NPC1	O15118-1.2	A183G	Neutral	0.077
NPC1	O15118-1.2	A183H	Neutral	0.186
NPC1	O15118-1.2	A183I	Neutral	0.094
NPC1	O15118-1.2	A183K	Neutral	0.106
NPC1	O15118-1.2	A183L	Neutral	0.097
NPC1	O15118-1.2	A183M	Neutral	0.111
NPC1	O15118-1.2	A183N	Neutral	0.135
NPC1	O15118-1.2	A183P	Neutral	0.108
NPC1	O15118-1.2	A183Q	Neutral	0.119
NPC1	O15118-1.2	A183R	Neutral	0.113
NPC1	O15118-1.2	A183S	Neutral	0.049
NPC1	O15118-1.2	A183T	Neutral	0.086
NPC1	O15118-1.2	A183V	Neutral	0.071
NPC1	O15118-1.2	A183W	Neutral	0.197
NPC1	O15118-1.2	A183Y	Neutral	0.183
NPC1	O15118-1.2	C184A	Pathogenic	0.814
NPC1	O15118-1.2	C184D	Pathogenic	0.899
NPC1	O15118-1.2	C184E	Pathogenic	0.939
NPC1	O15118-1.2	C184F	Pathogenic	0.915
NPC1	O15118-1.2	C184G	Pathogenic	0.934
NPC1	O15118-1.2	C184H	Pathogenic	0.934
NPC1	O15118-1.2	C184I	Pathogenic	0.873
NPC1	O15118-1.2	C184K	Pathogenic	0.915
NPC1	O15118-1.2	C184L	Pathogenic	0.876
NPC1	O15118-1.2	C184M	Pathogenic	0.892
NPC1	O15118-1.2	C184N	Pathogenic	0.907
NPC1	O15118-1.2	C184P	Pathogenic	0.936
NPC1	O15118-1.2	C184Q	Pathogenic	0.925
NPC1	O15118-1.2	C184R	Pathogenic	0.921
NPC1	O15118-1.2	C184S	Pathogenic	0.847
NPC1	O15118-1.2	C184T	Pathogenic	0.854
NPC1	O15118-1.2	C184V	Pathogenic	0.881
NPC1	O15118-1.2	C184W	Pathogenic	0.917
NPC1	O15118-1.2	C184Y	Pathogenic	0.936
NPC1	O15118-1.2	N185A	Neutral	0.44
NPC1	O15118-1.2	N185C	Neutral	0.452
NPC1	O15118-1.2	N185D	Neutral	0.215
NPC1	O15118-1.2	N185E	Neutral	0.306
NPC1	O15118-1.2	N185F	Neutral	0.429
NPC1	O15118-1.2	N185G	Neutral	0.311
NPC1	O15118-1.2	N185H	Neutral	0.201
NPC1	O15118-1.2	N185I	Neutral	0.411
NPC1	O15118-1.2	N185K	Neutral	0.315
NPC1	O15118-1.2	N185L	Neutral	0.42
NPC1	O15118-1.2	N185M	Neutral	0.365
NPC1	O15118-1.2	N185P	Neutral	0.374
NPC1	O15118-1.2	N185Q	Neutral	0.288
NPC1	O15118-1.2	N185R	Neutral	0.331
NPC1	O15118-1.2	N185S	Neutral	0.211
NPC1	O15118-1.2	N185T	Neutral	0.24
NPC1	O15118-1.2	N185V	Neutral	0.431
NPC1	O15118-1.2	N185W	Pathogenic	0.529
NPC1	O15118-1.2	N185Y	Neutral	0.411
NPC1	O15118-1.2	A186C	Neutral	0.328
NPC1	O15118-1.2	A186D	Neutral	0.487
NPC1	O15118-1.2	A186E	Neutral	0.43
NPC1	O15118-1.2	A186F	Pathogenic	0.52
NPC1	O15118-1.2	A186G	Neutral	0.355
NPC1	O15118-1.2	A186H	Pathogenic	0.602
NPC1	O15118-1.2	A186I	Neutral	0.407
NPC1	O15118-1.2	A186K	Neutral	0.439
NPC1	O15118-1.2	A186L	Neutral	0.415
NPC1	O15118-1.2	A186M	Neutral	0.454
NPC1	O15118-1.2	A186N	Pathogenic	0.509
NPC1	O15118-1.2	A186P	Neutral	0.445
NPC1	O15118-1.2	A186Q	Neutral	0.471
NPC1	O15118-1.2	A186R	Neutral	0.458
NPC1	O15118-1.2	A186S	Neutral	0.255
NPC1	O15118-1.2	A186T	Neutral	0.385
NPC1	O15118-1.2	A186V	Neutral	0.336
NPC1	O15118-1.2	A186W	Pathogenic	0.618
NPC1	O15118-1.2	A186Y	Pathogenic	0.597
NPC1	O15118-1.2	T187A	Neutral	0.134
NPC1	O15118-1.2	T187C	Neutral	0.14
NPC1	O15118-1.2	T187D	Neutral	0.125
NPC1	O15118-1.2	T187E	Neutral	0.139
NPC1	O15118-1.2	T187F	Neutral	0.184
NPC1	O15118-1.2	T187G	Neutral	0.26
NPC1	O15118-1.2	T187H	Neutral	0.245
NPC1	O15118-1.2	T187I	Neutral	0.125
NPC1	O15118-1.2	T187K	Neutral	0.144
NPC1	O15118-1.2	T187L	Neutral	0.129
NPC1	O15118-1.2	T187M	Neutral	0.147
NPC1	O15118-1.2	T187N	Neutral	0.093
NPC1	O15118-1.2	T187P	Neutral	0.147
NPC1	O15118-1.2	T187Q	Neutral	0.161
NPC1	O15118-1.2	T187R	Neutral	0.154
NPC1	O15118-1.2	T187S	Neutral	0.086
NPC1	O15118-1.2	T187V	Neutral	0.095
NPC1	O15118-1.2	T187W	Neutral	0.187
NPC1	O15118-1.2	T187Y	Neutral	0.236
NPC1	O15118-1.2	N188A	Neutral	0.308
NPC1	O15118-1.2	N188C	Neutral	0.318
NPC1	O15118-1.2	N188D	Neutral	0.134
NPC1	O15118-1.2	N188E	Neutral	0.199
NPC1	O15118-1.2	N188F	Neutral	0.298
NPC1	O15118-1.2	N188G	Neutral	0.203
NPC1	O15118-1.2	N188H	Neutral	0.124
NPC1	O15118-1.2	N188I	Neutral	0.283
NPC1	O15118-1.2	N188K	Neutral	0.206
NPC1	O15118-1.2	N188L	Neutral	0.29
NPC1	O15118-1.2	N188M	Neutral	0.245
NPC1	O15118-1.2	N188P	Neutral	0.252
NPC1	O15118-1.2	N188Q	Neutral	0.186
NPC1	O15118-1.2	N188R	Neutral	0.218
NPC1	O15118-1.2	N188S	Neutral	0.131
NPC1	O15118-1.2	N188T	Neutral	0.151
NPC1	O15118-1.2	N188V	Neutral	0.3
NPC1	O15118-1.2	N188W	Neutral	0.388
NPC1	O15118-1.2	N188Y	Neutral	0.283
NPC1	O15118-1.2	W189A	Pathogenic	0.927
NPC1	O15118-1.2	W189C	Pathogenic	0.906
NPC1	O15118-1.2	W189D	Pathogenic	0.918
NPC1	O15118-1.2	W189E	Pathogenic	0.878
NPC1	O15118-1.2	W189F	Pathogenic	0.746
NPC1	O15118-1.2	W189G	Pathogenic	0.897
NPC1	O15118-1.2	W189H	Pathogenic	0.856
NPC1	O15118-1.2	W189I	Pathogenic	0.936
NPC1	O15118-1.2	W189K	Pathogenic	0.845
NPC1	O15118-1.2	W189L	Pathogenic	0.906
NPC1	O15118-1.2	W189M	Pathogenic	0.849
NPC1	O15118-1.2	W189N	Pathogenic	0.92
NPC1	O15118-1.2	W189P	Pathogenic	0.949
NPC1	O15118-1.2	W189Q	Pathogenic	0.845
NPC1	O15118-1.2	W189R	Pathogenic	0.834
NPC1	O15118-1.2	W189S	Pathogenic	0.916
NPC1	O15118-1.2	W189T	Pathogenic	0.878
NPC1	O15118-1.2	W189V	Pathogenic	0.932
NPC1	O15118-1.2	W189Y	Pathogenic	0.593
NPC1	O15118-1.2	I190A	Neutral	0.319
NPC1	O15118-1.2	I190C	Neutral	0.343
NPC1	O15118-1.2	I190D	Neutral	0.38
NPC1	O15118-1.2	I190E	Neutral	0.365
NPC1	O15118-1.2	I190F	Neutral	0.283
NPC1	O15118-1.2	I190G	Pathogenic	0.602
NPC1	O15118-1.2	I190H	Neutral	0.413
NPC1	O15118-1.2	I190K	Neutral	0.333
NPC1	O15118-1.2	I190L	Neutral	0.142
NPC1	O15118-1.2	I190M	Neutral	0.173
NPC1	O15118-1.2	I190N	Neutral	0.386
NPC1	O15118-1.2	I190P	Pathogenic	0.503
NPC1	O15118-1.2	I190Q	Neutral	0.391
NPC1	O15118-1.2	I190R	Neutral	0.35
NPC1	O15118-1.2	I190S	Neutral	0.372
NPC1	O15118-1.2	I190T	Neutral	0.283
NPC1	O15118-1.2	I190V	Neutral	0.097
NPC1	O15118-1.2	I190W	Pathogenic	0.563
NPC1	O15118-1.2	I190Y	Neutral	0.314
NPC1	O15118-1.2	E191A	Neutral	0.122
NPC1	O15118-1.2	E191C	Neutral	0.239
NPC1	O15118-1.2	E191D	Neutral	0.047
NPC1	O15118-1.2	E191F	Neutral	0.143
NPC1	O15118-1.2	E191G	Neutral	0.202
NPC1	O15118-1.2	E191H	Neutral	0.076
NPC1	O15118-1.2	E191I	Neutral	0.134
NPC1	O15118-1.2	E191K	Neutral	0.066
NPC1	O15118-1.2	E191L	Neutral	0.138
NPC1	O15118-1.2	E191M	Neutral	0.113
NPC1	O15118-1.2	E191N	Neutral	0.097
NPC1	O15118-1.2	E191P	Neutral	0.095
NPC1	O15118-1.2	E191Q	Neutral	0.04
NPC1	O15118-1.2	E191R	Neutral	0.101
NPC1	O15118-1.2	E191S	Neutral	0.092
NPC1	O15118-1.2	E191T	Neutral	0.107
NPC1	O15118-1.2	E191V	Neutral	0.107
NPC1	O15118-1.2	E191W	Neutral	0.144
NPC1	O15118-1.2	E191Y	Neutral	0.134
NPC1	O15118-1.2	Y192A	Pathogenic	0.775
NPC1	O15118-1.2	Y192C	Pathogenic	0.792
NPC1	O15118-1.2	Y192D	Pathogenic	0.754
NPC1	O15118-1.2	Y192E	Pathogenic	0.662
NPC1	O15118-1.2	Y192F	Neutral	0.239
NPC1	O15118-1.2	Y192G	Pathogenic	0.837
NPC1	O15118-1.2	Y192H	Neutral	0.338
NPC1	O15118-1.2	Y192I	Pathogenic	0.61
NPC1	O15118-1.2	Y192K	Pathogenic	0.598
NPC1	O15118-1.2	Y192L	Pathogenic	0.618
NPC1	O15118-1.2	Y192M	Pathogenic	0.654
NPC1	O15118-1.2	Y192N	Pathogenic	0.682
NPC1	O15118-1.2	Y192P	Pathogenic	0.835
NPC1	O15118-1.2	Y192Q	Pathogenic	0.597
NPC1	O15118-1.2	Y192R	Pathogenic	0.598
NPC1	O15118-1.2	Y192S	Pathogenic	0.748
NPC1	O15118-1.2	Y192T	Pathogenic	0.744
NPC1	O15118-1.2	Y192V	Pathogenic	0.68
NPC1	O15118-1.2	Y192W	Neutral	0.304
NPC1	O15118-1.2	M193A	Pathogenic	0.789
NPC1	O15118-1.2	M193C	Pathogenic	0.806
NPC1	O15118-1.2	M193D	Pathogenic	0.83
NPC1	O15118-1.2	M193E	Pathogenic	0.757
NPC1	O15118-1.2	M193F	Pathogenic	0.685
NPC1	O15118-1.2	M193G	Pathogenic	0.891
NPC1	O15118-1.2	M193H	Pathogenic	0.792
NPC1	O15118-1.2	M193I	Pathogenic	0.579
NPC1	O15118-1.2	M193K	Pathogenic	0.647
NPC1	O15118-1.2	M193L	Neutral	0.491
NPC1	O15118-1.2	M193N	Pathogenic	0.773
NPC1	O15118-1.2	M193P	Pathogenic	0.846
NPC1	O15118-1.2	M193Q	Pathogenic	0.616
NPC1	O15118-1.2	M193R	Pathogenic	0.664
NPC1	O15118-1.2	M193S	Pathogenic	0.762
NPC1	O15118-1.2	M193T	Pathogenic	0.758
NPC1	O15118-1.2	M193V	Pathogenic	0.65
NPC1	O15118-1.2	M193W	Pathogenic	0.764
NPC1	O15118-1.2	M193Y	Pathogenic	0.784
NPC1	O15118-1.2	F194A	Pathogenic	0.541
NPC1	O15118-1.2	F194C	Pathogenic	0.568
NPC1	O15118-1.2	F194D	Pathogenic	0.512
NPC1	O15118-1.2	F194E	Neutral	0.495
NPC1	O15118-1.2	F194G	Pathogenic	0.637
NPC1	O15118-1.2	F194H	Neutral	0.357
NPC1	O15118-1.2	F194I	Neutral	0.386
NPC1	O15118-1.2	F194K	Neutral	0.427
NPC1	O15118-1.2	F194L	Neutral	0.38
NPC1	O15118-1.2	F194M	Neutral	0.344
NPC1	O15118-1.2	F194N	Pathogenic	0.518
NPC1	O15118-1.2	F194P	Pathogenic	0.718
NPC1	O15118-1.2	F194Q	Pathogenic	0.523
NPC1	O15118-1.2	F194R	Neutral	0.446
NPC1	O15118-1.2	F194S	Pathogenic	0.503
NPC1	O15118-1.2	F194T	Neutral	0.498
NPC1	O15118-1.2	F194V	Neutral	0.463
NPC1	O15118-1.2	F194W	Neutral	0.29
NPC1	O15118-1.2	F194Y	Neutral	0.128
NPC1	O15118-1.2	N195A	Neutral	0.3
NPC1	O15118-1.2	N195C	Neutral	0.31
NPC1	O15118-1.2	N195D	Neutral	0.13
NPC1	O15118-1.2	N195E	Neutral	0.194
NPC1	O15118-1.2	N195F	Neutral	0.291
NPC1	O15118-1.2	N195G	Neutral	0.198
NPC1	O15118-1.2	N195H	Neutral	0.121
NPC1	O15118-1.2	N195I	Neutral	0.276
NPC1	O15118-1.2	N195K	Neutral	0.2
NPC1	O15118-1.2	N195L	Neutral	0.283
NPC1	O15118-1.2	N195M	Neutral	0.239
NPC1	O15118-1.2	N195P	Neutral	0.246
NPC1	O15118-1.2	N195Q	Neutral	0.181
NPC1	O15118-1.2	N195R	Neutral	0.213
NPC1	O15118-1.2	N195S	Neutral	0.127
NPC1	O15118-1.2	N195T	Neutral	0.147
NPC1	O15118-1.2	N195V	Neutral	0.293
NPC1	O15118-1.2	N195W	Neutral	0.38
NPC1	O15118-1.2	N195Y	Neutral	0.276
NPC1	O15118-1.2	K196A	Neutral	0.162
NPC1	O15118-1.2	K196C	Neutral	0.229
NPC1	O15118-1.2	K196D	Neutral	0.193
NPC1	O15118-1.2	K196E	Neutral	0.087
NPC1	O15118-1.2	K196F	Neutral	0.145
NPC1	O15118-1.2	K196G	Neutral	0.261
NPC1	O15118-1.2	K196H	Neutral	0.131
NPC1	O15118-1.2	K196I	Neutral	0.153
NPC1	O15118-1.2	K196L	Neutral	0.112
NPC1	O15118-1.2	K196M	Neutral	0.091
NPC1	O15118-1.2	K196N	Neutral	0.13
NPC1	O15118-1.2	K196P	Neutral	0.128
NPC1	O15118-1.2	K196Q	Neutral	0.074
NPC1	O15118-1.2	K196R	Neutral	0.063
NPC1	O15118-1.2	K196S	Neutral	0.124
NPC1	O15118-1.2	K196T	Neutral	0.144
NPC1	O15118-1.2	K196V	Neutral	0.143
NPC1	O15118-1.2	K196W	Neutral	0.147
NPC1	O15118-1.2	K196Y	Neutral	0.136
NPC1	O15118-1.2	D197A	Neutral	0.192
NPC1	O15118-1.2	D197C	Neutral	0.2
NPC1	O15118-1.2	D197E	Neutral	0.063
NPC1	O15118-1.2	D197F	Neutral	0.194
NPC1	O15118-1.2	D197G	Neutral	0.167
NPC1	O15118-1.2	D197H	Neutral	0.149
NPC1	O15118-1.2	D197I	Neutral	0.184
NPC1	O15118-1.2	D197K	Neutral	0.195
NPC1	O15118-1.2	D197L	Neutral	0.255
NPC1	O15118-1.2	D197M	Neutral	0.214
NPC1	O15118-1.2	D197N	Neutral	0.083
NPC1	O15118-1.2	D197P	Neutral	0.109
NPC1	O15118-1.2	D197Q	Neutral	0.115
NPC1	O15118-1.2	D197R	Neutral	0.278
NPC1	O15118-1.2	D197S	Neutral	0.106
NPC1	O15118-1.2	D197T	Neutral	0.126
NPC1	O15118-1.2	D197V	Neutral	0.196
NPC1	O15118-1.2	D197W	Neutral	0.265
NPC1	O15118-1.2	D197Y	Neutral	0.248
NPC1	O15118-1.2	N198A	Pathogenic	0.692
NPC1	O15118-1.2	N198C	Pathogenic	0.702
NPC1	O15118-1.2	N198D	Neutral	0.438
NPC1	O15118-1.2	N198E	Pathogenic	0.557
NPC1	O15118-1.2	N198F	Pathogenic	0.682
NPC1	O15118-1.2	N198G	Pathogenic	0.563
NPC1	O15118-1.2	N198H	Neutral	0.417
NPC1	O15118-1.2	N198I	Pathogenic	0.666
NPC1	O15118-1.2	N198K	Pathogenic	0.567
NPC1	O15118-1.2	N198L	Pathogenic	0.674
NPC1	O15118-1.2	N198M	Pathogenic	0.621
NPC1	O15118-1.2	N198P	Pathogenic	0.63
NPC1	O15118-1.2	N198Q	Pathogenic	0.536
NPC1	O15118-1.2	N198R	Pathogenic	0.585
NPC1	O15118-1.2	N198S	Neutral	0.433
NPC1	O15118-1.2	N198T	Neutral	0.474
NPC1	O15118-1.2	N198V	Pathogenic	0.684
NPC1	O15118-1.2	N198W	Pathogenic	0.762
NPC1	O15118-1.2	N198Y	Pathogenic	0.665
NPC1	O15118-1.2	G199A	Neutral	0.3
NPC1	O15118-1.2	G199C	Pathogenic	0.55
NPC1	O15118-1.2	G199D	Neutral	0.385
NPC1	O15118-1.2	G199E	Pathogenic	0.518
NPC1	O15118-1.2	G199F	Pathogenic	0.557
NPC1	O15118-1.2	G199H	Pathogenic	0.573
NPC1	O15118-1.2	G199I	Pathogenic	0.633
NPC1	O15118-1.2	G199K	Pathogenic	0.528
NPC1	O15118-1.2	G199L	Pathogenic	0.641
NPC1	O15118-1.2	G199M	Pathogenic	0.586
NPC1	O15118-1.2	G199N	Neutral	0.317
NPC1	O15118-1.2	G199P	Neutral	0.482
NPC1	O15118-1.2	G199Q	Pathogenic	0.56
NPC1	O15118-1.2	G199R	Pathogenic	0.546
NPC1	O15118-1.2	G199S	Neutral	0.328
NPC1	O15118-1.2	G199T	Pathogenic	0.525
NPC1	O15118-1.2	G199V	Pathogenic	0.56
NPC1	O15118-1.2	G199W	Neutral	0.465
NPC1	O15118-1.2	G199Y	Pathogenic	0.632
NPC1	O15118-1.2	Q200A	Neutral	0.305
NPC1	O15118-1.2	Q200C	Neutral	0.404
NPC1	O15118-1.2	Q200D	Neutral	0.204
NPC1	O15118-1.2	Q200E	Neutral	0.1
NPC1	O15118-1.2	Q200F	Neutral	0.332
NPC1	O15118-1.2	Q200G	Neutral	0.445
NPC1	O15118-1.2	Q200H	Neutral	0.196
NPC1	O15118-1.2	Q200I	Neutral	0.316
NPC1	O15118-1.2	Q200K	Neutral	0.138
NPC1	O15118-1.2	Q200L	Neutral	0.245
NPC1	O15118-1.2	Q200M	Neutral	0.149
NPC1	O15118-1.2	Q200N	Neutral	0.208
NPC1	O15118-1.2	Q200P	Neutral	0.25
NPC1	O15118-1.2	Q200R	Neutral	0.147
NPC1	O15118-1.2	Q200S	Neutral	0.244
NPC1	O15118-1.2	Q200T	Neutral	0.276
NPC1	O15118-1.2	Q200V	Neutral	0.275
NPC1	O15118-1.2	Q200W	Neutral	0.255
NPC1	O15118-1.2	Q200Y	Neutral	0.239
NPC1	O15118-1.2	A201C	Neutral	0.204
NPC1	O15118-1.2	A201D	Neutral	0.333
NPC1	O15118-1.2	A201E	Neutral	0.283
NPC1	O15118-1.2	A201F	Neutral	0.363
NPC1	O15118-1.2	A201G	Neutral	0.224
NPC1	O15118-1.2	A201H	Neutral	0.442
NPC1	O15118-1.2	A201I	Neutral	0.265
NPC1	O15118-1.2	A201K	Neutral	0.292
NPC1	O15118-1.2	A201L	Neutral	0.272
NPC1	O15118-1.2	A201M	Neutral	0.304
NPC1	O15118-1.2	A201N	Neutral	0.352
NPC1	O15118-1.2	A201P	Neutral	0.296
NPC1	O15118-1.2	A201Q	Neutral	0.319
NPC1	O15118-1.2	A201R	Neutral	0.307
NPC1	O15118-1.2	A201S	Neutral	0.152
NPC1	O15118-1.2	A201T	Neutral	0.247
NPC1	O15118-1.2	A201V	Neutral	0.21
NPC1	O15118-1.2	A201W	Neutral	0.46
NPC1	O15118-1.2	A201Y	Neutral	0.438
NPC1	O15118-1.2	P202A	Pathogenic	0.848
NPC1	O15118-1.2	P202C	Pathogenic	0.919
NPC1	O15118-1.2	P202D	Pathogenic	0.774
NPC1	O15118-1.2	P202E	Pathogenic	0.799
NPC1	O15118-1.2	P202F	Pathogenic	0.942
NPC1	O15118-1.2	P202G	Pathogenic	0.893
NPC1	O15118-1.2	P202H	Pathogenic	0.889
NPC1	O15118-1.2	P202I	Pathogenic	0.912
NPC1	O15118-1.2	P202K	Pathogenic	0.806
NPC1	O15118-1.2	P202L	Pathogenic	0.914
NPC1	O15118-1.2	P202M	Pathogenic	0.895
NPC1	O15118-1.2	P202N	Pathogenic	0.846
NPC1	O15118-1.2	P202Q	Pathogenic	0.825
NPC1	O15118-1.2	P202R	Pathogenic	0.868
NPC1	O15118-1.2	P202S	Pathogenic	0.828
NPC1	O15118-1.2	P202T	Pathogenic	0.829
NPC1	O15118-1.2	P202V	Pathogenic	0.884
NPC1	O15118-1.2	P202W	Pathogenic	0.943
NPC1	O15118-1.2	P202Y	Pathogenic	0.938
NPC1	O15118-1.2	F203A	Pathogenic	0.85
NPC1	O15118-1.2	F203C	Pathogenic	0.863
NPC1	O15118-1.2	F203D	Pathogenic	0.834
NPC1	O15118-1.2	F203E	Pathogenic	0.825
NPC1	O15118-1.2	F203G	Pathogenic	0.894
NPC1	O15118-1.2	F203H	Pathogenic	0.728
NPC1	O15118-1.2	F203I	Pathogenic	0.751
NPC1	O15118-1.2	F203K	Pathogenic	0.782
NPC1	O15118-1.2	F203L	Pathogenic	0.747
NPC1	O15118-1.2	F203M	Pathogenic	0.716
NPC1	O15118-1.2	F203N	Pathogenic	0.838
NPC1	O15118-1.2	F203P	Pathogenic	0.924
NPC1	O15118-1.2	F203Q	Pathogenic	0.84
NPC1	O15118-1.2	F203R	Pathogenic	0.794
NPC1	O15118-1.2	F203S	Pathogenic	0.83
NPC1	O15118-1.2	F203T	Pathogenic	0.826
NPC1	O15118-1.2	F203V	Pathogenic	0.806
NPC1	O15118-1.2	F203W	Pathogenic	0.662
NPC1	O15118-1.2	F203Y	Neutral	0.413
NPC1	O15118-1.2	T204A	Neutral	0.09
NPC1	O15118-1.2	T204C	Neutral	0.094
NPC1	O15118-1.2	T204D	Neutral	0.083
NPC1	O15118-1.2	T204E	Neutral	0.094
NPC1	O15118-1.2	T204F	Neutral	0.126
NPC1	O15118-1.2	T204G	Neutral	0.183
NPC1	O15118-1.2	T204H	Neutral	0.172
NPC1	O15118-1.2	T204I	Neutral	0.083
NPC1	O15118-1.2	T204K	Neutral	0.097
NPC1	O15118-1.2	T204L	Neutral	0.086
NPC1	O15118-1.2	T204M	Neutral	0.099
NPC1	O15118-1.2	T204N	Neutral	0.062
NPC1	O15118-1.2	T204P	Neutral	0.099
NPC1	O15118-1.2	T204Q	Neutral	0.109
NPC1	O15118-1.2	T204R	Neutral	0.104
NPC1	O15118-1.2	T204S	Neutral	0.056
NPC1	O15118-1.2	T204V	Neutral	0.063
NPC1	O15118-1.2	T204W	Neutral	0.127
NPC1	O15118-1.2	T204Y	Neutral	0.164
NPC1	O15118-1.2	I205A	Pathogenic	0.683
NPC1	O15118-1.2	I205C	Pathogenic	0.706
NPC1	O15118-1.2	I205D	Pathogenic	0.738
NPC1	O15118-1.2	I205E	Pathogenic	0.725
NPC1	O15118-1.2	I205F	Pathogenic	0.645
NPC1	O15118-1.2	I205G	Pathogenic	0.874
NPC1	O15118-1.2	I205H	Pathogenic	0.764
NPC1	O15118-1.2	I205K	Pathogenic	0.696
NPC1	O15118-1.2	I205L	Neutral	0.432
NPC1	O15118-1.2	I205M	Neutral	0.49
NPC1	O15118-1.2	I205N	Pathogenic	0.743
NPC1	O15118-1.2	I205P	Pathogenic	0.823
NPC1	O15118-1.2	I205Q	Pathogenic	0.746
NPC1	O15118-1.2	I205R	Pathogenic	0.712
NPC1	O15118-1.2	I205S	Pathogenic	0.732
NPC1	O15118-1.2	I205T	Pathogenic	0.644
NPC1	O15118-1.2	I205V	Neutral	0.331
NPC1	O15118-1.2	I205W	Pathogenic	0.856
NPC1	O15118-1.2	I205Y	Pathogenic	0.678
NPC1	O15118-1.2	T206A	Neutral	0.409
NPC1	O15118-1.2	T206C	Neutral	0.42
NPC1	O15118-1.2	T206D	Neutral	0.389
NPC1	O15118-1.2	T206E	Neutral	0.42
NPC1	O15118-1.2	T206F	Pathogenic	0.502
NPC1	O15118-1.2	T206G	Pathogenic	0.611
NPC1	O15118-1.2	T206H	Pathogenic	0.592
NPC1	O15118-1.2	T206I	Neutral	0.39
NPC1	O15118-1.2	T206K	Neutral	0.43
NPC1	O15118-1.2	T206L	Neutral	0.398
NPC1	O15118-1.2	T206M	Neutral	0.436
NPC1	O15118-1.2	T206N	Neutral	0.315
NPC1	O15118-1.2	T206P	Neutral	0.436
NPC1	O15118-1.2	T206Q	Neutral	0.462
NPC1	O15118-1.2	T206R	Neutral	0.448
NPC1	O15118-1.2	T206S	Neutral	0.295
NPC1	O15118-1.2	T206V	Neutral	0.32
NPC1	O15118-1.2	T206W	Pathogenic	0.506
NPC1	O15118-1.2	T206Y	Pathogenic	0.579
NPC1	O15118-1.2	P207A	Pathogenic	0.642
NPC1	O15118-1.2	P207C	Pathogenic	0.784
NPC1	O15118-1.2	P207D	Pathogenic	0.523
NPC1	O15118-1.2	P207E	Pathogenic	0.561
NPC1	O15118-1.2	P207F	Pathogenic	0.839
NPC1	O15118-1.2	P207G	Pathogenic	0.727
NPC1	O15118-1.2	P207H	Pathogenic	0.719
NPC1	O15118-1.2	P207I	Pathogenic	0.768
NPC1	O15118-1.2	P207K	Pathogenic	0.571
NPC1	O15118-1.2	P207L	Pathogenic	0.774
NPC1	O15118-1.2	P207M	Pathogenic	0.731
NPC1	O15118-1.2	P207N	Pathogenic	0.637
NPC1	O15118-1.2	P207Q	Pathogenic	0.602
NPC1	O15118-1.2	P207R	Pathogenic	0.678
NPC1	O15118-1.2	P207S	Pathogenic	0.606
NPC1	O15118-1.2	P207T	Pathogenic	0.609
NPC1	O15118-1.2	P207V	Pathogenic	0.709
NPC1	O15118-1.2	P207W	Pathogenic	0.842
NPC1	O15118-1.2	P207Y	Pathogenic	0.829
NPC1	O15118-1.2	V208A	Neutral	0.259
NPC1	O15118-1.2	V208C	Neutral	0.364
NPC1	O15118-1.2	V208D	Neutral	0.401
NPC1	O15118-1.2	V208E	Neutral	0.31
NPC1	O15118-1.2	V208F	Neutral	0.353
NPC1	O15118-1.2	V208G	Pathogenic	0.529
NPC1	O15118-1.2	V208H	Neutral	0.474
NPC1	O15118-1.2	V208I	Neutral	0.098
NPC1	O15118-1.2	V208K	Neutral	0.318
NPC1	O15118-1.2	V208L	Neutral	0.196
NPC1	O15118-1.2	V208M	Neutral	0.222
NPC1	O15118-1.2	V208N	Neutral	0.408
NPC1	O15118-1.2	V208P	Neutral	0.429
NPC1	O15118-1.2	V208Q	Neutral	0.347
NPC1	O15118-1.2	V208R	Neutral	0.425
NPC1	O15118-1.2	V208S	Neutral	0.394
NPC1	O15118-1.2	V208T	Neutral	0.227
NPC1	O15118-1.2	V208W	Pathogenic	0.546
NPC1	O15118-1.2	V208Y	Neutral	0.386
NPC1	O15118-1.2	F209A	Neutral	0.491
NPC1	O15118-1.2	F209C	Pathogenic	0.519
NPC1	O15118-1.2	F209D	Neutral	0.462
NPC1	O15118-1.2	F209E	Neutral	0.446
NPC1	O15118-1.2	F209G	Pathogenic	0.59
NPC1	O15118-1.2	F209H	Neutral	0.313
NPC1	O15118-1.2	F209I	Neutral	0.34
NPC1	O15118-1.2	F209K	Neutral	0.38
NPC1	O15118-1.2	F209L	Neutral	0.334
NPC1	O15118-1.2	F209M	Neutral	0.301
NPC1	O15118-1.2	F209N	Neutral	0.468
NPC1	O15118-1.2	F209P	Pathogenic	0.676
NPC1	O15118-1.2	F209Q	Neutral	0.473
NPC1	O15118-1.2	F209R	Neutral	0.397
NPC1	O15118-1.2	F209S	Neutral	0.454
NPC1	O15118-1.2	F209T	Neutral	0.448
NPC1	O15118-1.2	F209V	Neutral	0.414
NPC1	O15118-1.2	F209W	Neutral	0.251
NPC1	O15118-1.2	F209Y	Neutral	0.107
NPC1	O15118-1.2	S210A	Neutral	0.27
NPC1	O15118-1.2	S210C	Neutral	0.4
NPC1	O15118-1.2	S210D	Neutral	0.34
NPC1	O15118-1.2	S210E	Neutral	0.375
NPC1	O15118-1.2	S210F	Pathogenic	0.503
NPC1	O15118-1.2	S210G	Neutral	0.404
NPC1	O15118-1.2	S210H	Pathogenic	0.518
NPC1	O15118-1.2	S210I	Neutral	0.485
NPC1	O15118-1.2	S210K	Neutral	0.384
NPC1	O15118-1.2	S210L	Neutral	0.493
NPC1	O15118-1.2	S210M	Neutral	0.436
NPC1	O15118-1.2	S210N	Neutral	0.276
NPC1	O15118-1.2	S210P	Neutral	0.428
NPC1	O15118-1.2	S210Q	Neutral	0.415
NPC1	O15118-1.2	S210R	Neutral	0.497
NPC1	O15118-1.2	S210T	Neutral	0.291
NPC1	O15118-1.2	S210V	Pathogenic	0.505
NPC1	O15118-1.2	S210W	Pathogenic	0.602
NPC1	O15118-1.2	S210Y	Pathogenic	0.58
NPC1	O15118-1.2	D211A	Pathogenic	0.781
NPC1	O15118-1.2	D211C	Pathogenic	0.789
NPC1	O15118-1.2	D211E	Pathogenic	0.502
NPC1	O15118-1.2	D211F	Pathogenic	0.784
NPC1	O15118-1.2	D211G	Pathogenic	0.751
NPC1	O15118-1.2	D211H	Pathogenic	0.724
NPC1	O15118-1.2	D211I	Pathogenic	0.771
NPC1	O15118-1.2	D211K	Pathogenic	0.785
NPC1	O15118-1.2	D211L	Pathogenic	0.837
NPC1	O15118-1.2	D211M	Pathogenic	0.803
NPC1	O15118-1.2	D211N	Pathogenic	0.575
NPC1	O15118-1.2	D211P	Pathogenic	0.648
NPC1	O15118-1.2	D211Q	Pathogenic	0.661
NPC1	O15118-1.2	D211R	Pathogenic	0.852
NPC1	O15118-1.2	D211S	Pathogenic	0.641
NPC1	O15118-1.2	D211T	Pathogenic	0.684
NPC1	O15118-1.2	D211V	Pathogenic	0.785
NPC1	O15118-1.2	D211W	Pathogenic	0.844
NPC1	O15118-1.2	D211Y	Pathogenic	0.832
NPC1	O15118-1.2	F212A	Neutral	0.149
NPC1	O15118-1.2	F212C	Neutral	0.164
NPC1	O15118-1.2	F212D	Neutral	0.135
NPC1	O15118-1.2	F212E	Neutral	0.128
NPC1	O15118-1.2	F212G	Neutral	0.207
NPC1	O15118-1.2	F212H	Neutral	0.076
NPC1	O15118-1.2	F212I	Neutral	0.086
NPC1	O15118-1.2	F212K	Neutral	0.1
NPC1	O15118-1.2	F212L	Neutral	0.084
NPC1	O15118-1.2	F212M	Neutral	0.073
NPC1	O15118-1.2	F212N	Neutral	0.138
NPC1	O15118-1.2	F212P	Neutral	0.275
NPC1	O15118-1.2	F212Q	Neutral	0.14
NPC1	O15118-1.2	F212R	Neutral	0.107
NPC1	O15118-1.2	F212S	Neutral	0.131
NPC1	O15118-1.2	F212T	Neutral	0.129
NPC1	O15118-1.2	F212V	Neutral	0.114
NPC1	O15118-1.2	F212W	Neutral	0.057
NPC1	O15118-1.2	F212Y	Neutral	0.021
NPC1	O15118-1.2	P213A	Pathogenic	0.676
NPC1	O15118-1.2	P213C	Pathogenic	0.808
NPC1	O15118-1.2	P213D	Pathogenic	0.56
NPC1	O15118-1.2	P213E	Pathogenic	0.598
NPC1	O15118-1.2	P213F	Pathogenic	0.859
NPC1	O15118-1.2	P213G	Pathogenic	0.756
NPC1	O15118-1.2	P213H	Pathogenic	0.749
NPC1	O15118-1.2	P213I	Pathogenic	0.794
NPC1	O15118-1.2	P213K	Pathogenic	0.607
NPC1	O15118-1.2	P213L	Pathogenic	0.799
NPC1	O15118-1.2	P213M	Pathogenic	0.76
NPC1	O15118-1.2	P213N	Pathogenic	0.671
NPC1	O15118-1.2	P213Q	Pathogenic	0.638
NPC1	O15118-1.2	P213R	Pathogenic	0.71
NPC1	O15118-1.2	P213S	Pathogenic	0.642
NPC1	O15118-1.2	P213T	Pathogenic	0.645
NPC1	O15118-1.2	P213V	Pathogenic	0.739
NPC1	O15118-1.2	P213W	Pathogenic	0.861
NPC1	O15118-1.2	P213Y	Pathogenic	0.85
NPC1	O15118-1.2	V214A	Neutral	0.194
NPC1	O15118-1.2	V214C	Neutral	0.283
NPC1	O15118-1.2	V214D	Neutral	0.316
NPC1	O15118-1.2	V214E	Neutral	0.236
NPC1	O15118-1.2	V214F	Neutral	0.274
NPC1	O15118-1.2	V214G	Neutral	0.436
NPC1	O15118-1.2	V214H	Neutral	0.383
NPC1	O15118-1.2	V214I	Neutral	0.07
NPC1	O15118-1.2	V214K	Neutral	0.243
NPC1	O15118-1.2	V214L	Neutral	0.144
NPC1	O15118-1.2	V214M	Neutral	0.164
NPC1	O15118-1.2	V214N	Neutral	0.322
NPC1	O15118-1.2	V214P	Neutral	0.341
NPC1	O15118-1.2	V214Q	Neutral	0.268
NPC1	O15118-1.2	V214R	Neutral	0.337
NPC1	O15118-1.2	V214S	Neutral	0.309
NPC1	O15118-1.2	V214T	Neutral	0.168
NPC1	O15118-1.2	V214W	Neutral	0.453
NPC1	O15118-1.2	V214Y	Neutral	0.302
NPC1	O15118-1.2	H215A	Pathogenic	0.525
NPC1	O15118-1.2	H215C	Pathogenic	0.537
NPC1	O15118-1.2	H215D	Neutral	0.338
NPC1	O15118-1.2	H215E	Neutral	0.246
NPC1	O15118-1.2	H215F	Neutral	0.272
NPC1	O15118-1.2	H215G	Pathogenic	0.557
NPC1	O15118-1.2	H215I	Neutral	0.43
NPC1	O15118-1.2	H215K	Neutral	0.309
NPC1	O15118-1.2	H215L	Neutral	0.438
NPC1	O15118-1.2	H215M	Neutral	0.383
NPC1	O15118-1.2	H215N	Neutral	0.195
NPC1	O15118-1.2	H215P	Neutral	0.456
NPC1	O15118-1.2	H215Q	Neutral	0.266
NPC1	O15118-1.2	H215R	Neutral	0.247
NPC1	O15118-1.2	H215S	Neutral	0.421
NPC1	O15118-1.2	H215T	Neutral	0.49
NPC1	O15118-1.2	H215V	Neutral	0.489
NPC1	O15118-1.2	H215W	Neutral	0.359
NPC1	O15118-1.2	H215Y	Neutral	0.138
NPC1	O15118-1.2	G216A	Pathogenic	0.668
NPC1	O15118-1.2	G216C	Pathogenic	0.852
NPC1	O15118-1.2	G216D	Pathogenic	0.746
NPC1	O15118-1.2	G216E	Pathogenic	0.834
NPC1	O15118-1.2	G216F	Pathogenic	0.855
NPC1	O15118-1.2	G216H	Pathogenic	0.863
NPC1	O15118-1.2	G216I	Pathogenic	0.89
NPC1	O15118-1.2	G216K	Pathogenic	0.84
NPC1	O15118-1.2	G216L	Pathogenic	0.893
NPC1	O15118-1.2	G216M	Pathogenic	0.869
NPC1	O15118-1.2	G216N	Pathogenic	0.685
NPC1	O15118-1.2	G216P	Pathogenic	0.814
NPC1	O15118-1.2	G216Q	Pathogenic	0.856
NPC1	O15118-1.2	G216R	Pathogenic	0.85
NPC1	O15118-1.2	G216S	Pathogenic	0.696
NPC1	O15118-1.2	G216T	Pathogenic	0.838
NPC1	O15118-1.2	G216V	Pathogenic	0.856
NPC1	O15118-1.2	G216W	Pathogenic	0.803
NPC1	O15118-1.2	G216Y	Pathogenic	0.89
NPC1	O15118-1.2	M217A	Pathogenic	0.635
NPC1	O15118-1.2	M217C	Pathogenic	0.659
NPC1	O15118-1.2	M217D	Pathogenic	0.694
NPC1	O15118-1.2	M217E	Pathogenic	0.591
NPC1	O15118-1.2	M217F	Pathogenic	0.502
NPC1	O15118-1.2	M217G	Pathogenic	0.792
NPC1	O15118-1.2	M217H	Pathogenic	0.639
NPC1	O15118-1.2	M217I	Neutral	0.39
NPC1	O15118-1.2	M217K	Neutral	0.461
NPC1	O15118-1.2	M217L	Neutral	0.31
NPC1	O15118-1.2	M217N	Pathogenic	0.613
NPC1	O15118-1.2	M217P	Pathogenic	0.718
NPC1	O15118-1.2	M217Q	Neutral	0.427
NPC1	O15118-1.2	M217R	Neutral	0.479
NPC1	O15118-1.2	M217S	Pathogenic	0.599
NPC1	O15118-1.2	M217T	Pathogenic	0.593
NPC1	O15118-1.2	M217V	Neutral	0.463
NPC1	O15118-1.2	M217W	Pathogenic	0.601
NPC1	O15118-1.2	M217Y	Pathogenic	0.629
NPC1	O15118-1.2	E218A	Neutral	0.209
NPC1	O15118-1.2	E218C	Neutral	0.374
NPC1	O15118-1.2	E218D	Neutral	0.086
NPC1	O15118-1.2	E218F	Neutral	0.241
NPC1	O15118-1.2	E218G	Neutral	0.326
NPC1	O15118-1.2	E218H	Neutral	0.135
NPC1	O15118-1.2	E218I	Neutral	0.228
NPC1	O15118-1.2	E218K	Neutral	0.119
NPC1	O15118-1.2	E218L	Neutral	0.234
NPC1	O15118-1.2	E218M	Neutral	0.195
NPC1	O15118-1.2	E218N	Neutral	0.169
NPC1	O15118-1.2	E218P	Neutral	0.167
NPC1	O15118-1.2	E218Q	Neutral	0.073
NPC1	O15118-1.2	E218R	Neutral	0.176
NPC1	O15118-1.2	E218S	Neutral	0.163
NPC1	O15118-1.2	E218T	Neutral	0.187
NPC1	O15118-1.2	E218V	Neutral	0.186
NPC1	O15118-1.2	E218W	Neutral	0.244
NPC1	O15118-1.2	E218Y	Neutral	0.227
NPC1	O15118-1.2	P219A	Pathogenic	0.935
NPC1	O15118-1.2	P219C	Pathogenic	0.967
NPC1	O15118-1.2	P219D	Pathogenic	0.897
NPC1	O15118-1.2	P219E	Pathogenic	0.911
NPC1	O15118-1.2	P219F	Pathogenic	0.977
NPC1	O15118-1.2	P219G	Pathogenic	0.955
NPC1	O15118-1.2	P219H	Pathogenic	0.953
NPC1	O15118-1.2	P219I	Pathogenic	0.964
NPC1	O15118-1.2	P219K	Pathogenic	0.914
NPC1	O15118-1.2	P219L	Pathogenic	0.965
NPC1	O15118-1.2	P219M	Pathogenic	0.956
NPC1	O15118-1.2	P219N	Pathogenic	0.933
NPC1	O15118-1.2	P219Q	Pathogenic	0.923
NPC1	O15118-1.2	P219R	Pathogenic	0.944
NPC1	O15118-1.2	P219S	Pathogenic	0.925
NPC1	O15118-1.2	P219T	Pathogenic	0.926
NPC1	O15118-1.2	P219V	Pathogenic	0.951
NPC1	O15118-1.2	P219W	Pathogenic	0.977
NPC1	O15118-1.2	P219Y	Pathogenic	0.975
NPC1	O15118-1.2	M220A	Pathogenic	0.755
NPC1	O15118-1.2	M220C	Pathogenic	0.774
NPC1	O15118-1.2	M220D	Pathogenic	0.801
NPC1	O15118-1.2	M220E	Pathogenic	0.719
NPC1	O15118-1.2	M220F	Pathogenic	0.641
NPC1	O15118-1.2	M220G	Pathogenic	0.871
NPC1	O15118-1.2	M220H	Pathogenic	0.758
NPC1	O15118-1.2	M220I	Pathogenic	0.531
NPC1	O15118-1.2	M220K	Pathogenic	0.602
NPC1	O15118-1.2	M220L	Neutral	0.443
NPC1	O15118-1.2	M220N	Pathogenic	0.737
NPC1	O15118-1.2	M220P	Pathogenic	0.819
NPC1	O15118-1.2	M220Q	Pathogenic	0.569
NPC1	O15118-1.2	M220R	Pathogenic	0.62
NPC1	O15118-1.2	M220S	Pathogenic	0.726
NPC1	O15118-1.2	M220T	Pathogenic	0.721
NPC1	O15118-1.2	M220V	Pathogenic	0.604
NPC1	O15118-1.2	M220W	Pathogenic	0.728
NPC1	O15118-1.2	M220Y	Pathogenic	0.75
NPC1	O15118-1.2	N221A	Pathogenic	0.816
NPC1	O15118-1.2	N221C	Pathogenic	0.823
NPC1	O15118-1.2	N221D	Pathogenic	0.606
NPC1	O15118-1.2	N221E	Pathogenic	0.713
NPC1	O15118-1.2	N221F	Pathogenic	0.809
NPC1	O15118-1.2	N221G	Pathogenic	0.718
NPC1	O15118-1.2	N221H	Pathogenic	0.586
NPC1	O15118-1.2	N221I	Pathogenic	0.798
NPC1	O15118-1.2	N221K	Pathogenic	0.721
NPC1	O15118-1.2	N221L	Pathogenic	0.803
NPC1	O15118-1.2	N221M	Pathogenic	0.764
NPC1	O15118-1.2	N221P	Pathogenic	0.771
NPC1	O15118-1.2	N221Q	Pathogenic	0.695
NPC1	O15118-1.2	N221R	Pathogenic	0.736
NPC1	O15118-1.2	N221S	Pathogenic	0.601
NPC1	O15118-1.2	N221T	Pathogenic	0.64
NPC1	O15118-1.2	N221V	Pathogenic	0.81
NPC1	O15118-1.2	N221W	Pathogenic	0.863
NPC1	O15118-1.2	N221Y	Pathogenic	0.797
NPC1	O15118-1.2	N222A	Neutral	0.178
NPC1	O15118-1.2	N222C	Neutral	0.185
NPC1	O15118-1.2	N222D	Neutral	0.07
NPC1	O15118-1.2	N222E	Neutral	0.109
NPC1	O15118-1.2	N222F	Neutral	0.172
NPC1	O15118-1.2	N222G	Neutral	0.111
NPC1	O15118-1.2	N222H	Neutral	0.065
NPC1	O15118-1.2	N222I	Neutral	0.162
NPC1	O15118-1.2	N222K	Neutral	0.113
NPC1	O15118-1.2	N222L	Neutral	0.167
NPC1	O15118-1.2	N222M	Neutral	0.137
NPC1	O15118-1.2	N222P	Neutral	0.142
NPC1	O15118-1.2	N222Q	Neutral	0.101
NPC1	O15118-1.2	N222R	Neutral	0.12
NPC1	O15118-1.2	N222S	Neutral	0.069
NPC1	O15118-1.2	N222T	Neutral	0.08
NPC1	O15118-1.2	N222V	Neutral	0.173
NPC1	O15118-1.2	N222W	Neutral	0.237
NPC1	O15118-1.2	N222Y	Neutral	0.162
NPC1	O15118-1.2	A223C	Neutral	0.201
NPC1	O15118-1.2	A223D	Neutral	0.329
NPC1	O15118-1.2	A223E	Neutral	0.279
NPC1	O15118-1.2	A223F	Neutral	0.358
NPC1	O15118-1.2	A223G	Neutral	0.221
NPC1	O15118-1.2	A223H	Neutral	0.438
NPC1	O15118-1.2	A223I	Neutral	0.261
NPC1	O15118-1.2	A223K	Neutral	0.288
NPC1	O15118-1.2	A223L	Neutral	0.268
NPC1	O15118-1.2	A223M	Neutral	0.3
NPC1	O15118-1.2	A223N	Neutral	0.348
NPC1	O15118-1.2	A223P	Neutral	0.292
NPC1	O15118-1.2	A223Q	Neutral	0.315
NPC1	O15118-1.2	A223R	Neutral	0.303
NPC1	O15118-1.2	A223S	Neutral	0.15
NPC1	O15118-1.2	A223T	Neutral	0.244
NPC1	O15118-1.2	A223V	Neutral	0.207
NPC1	O15118-1.2	A223W	Neutral	0.455
NPC1	O15118-1.2	A223Y	Neutral	0.433
NPC1	O15118-1.2	T224A	Pathogenic	0.634
NPC1	O15118-1.2	T224C	Pathogenic	0.645
NPC1	O15118-1.2	T224D	Pathogenic	0.614
NPC1	O15118-1.2	T224E	Pathogenic	0.644
NPC1	O15118-1.2	T224F	Pathogenic	0.716
NPC1	O15118-1.2	T224G	Pathogenic	0.797
NPC1	O15118-1.2	T224H	Pathogenic	0.784
NPC1	O15118-1.2	T224I	Pathogenic	0.615
NPC1	O15118-1.2	T224K	Pathogenic	0.653
NPC1	O15118-1.2	T224L	Pathogenic	0.623
NPC1	O15118-1.2	T224M	Pathogenic	0.659
NPC1	O15118-1.2	T224N	Pathogenic	0.535
NPC1	O15118-1.2	T224P	Pathogenic	0.659
NPC1	O15118-1.2	T224Q	Pathogenic	0.682
NPC1	O15118-1.2	T224R	Pathogenic	0.67
NPC1	O15118-1.2	T224S	Pathogenic	0.511
NPC1	O15118-1.2	T224V	Pathogenic	0.54
NPC1	O15118-1.2	T224W	Pathogenic	0.719
NPC1	O15118-1.2	T224Y	Pathogenic	0.775
NPC1	O15118-1.2	K225A	Neutral	0.411
NPC1	O15118-1.2	K225C	Pathogenic	0.519
NPC1	O15118-1.2	K225D	Neutral	0.464
NPC1	O15118-1.2	K225E	Neutral	0.255
NPC1	O15118-1.2	K225F	Neutral	0.38
NPC1	O15118-1.2	K225G	Pathogenic	0.561
NPC1	O15118-1.2	K225H	Neutral	0.352
NPC1	O15118-1.2	K225I	Neutral	0.394
NPC1	O15118-1.2	K225L	Neutral	0.314
NPC1	O15118-1.2	K225M	Neutral	0.267
NPC1	O15118-1.2	K225N	Neutral	0.35
NPC1	O15118-1.2	K225P	Neutral	0.347
NPC1	O15118-1.2	K225Q	Neutral	0.225
NPC1	O15118-1.2	K225R	Neutral	0.194
NPC1	O15118-1.2	K225S	Neutral	0.339
NPC1	O15118-1.2	K225T	Neutral	0.378
NPC1	O15118-1.2	K225V	Neutral	0.376
NPC1	O15118-1.2	K225W	Neutral	0.384
NPC1	O15118-1.2	K225Y	Neutral	0.363
NPC1	O15118-1.2	G226A	Neutral	0.474
NPC1	O15118-1.2	G226C	Pathogenic	0.72
NPC1	O15118-1.2	G226D	Pathogenic	0.568
NPC1	O15118-1.2	G226E	Pathogenic	0.692
NPC1	O15118-1.2	G226F	Pathogenic	0.726
NPC1	O15118-1.2	G226H	Pathogenic	0.738
NPC1	O15118-1.2	G226I	Pathogenic	0.784
NPC1	O15118-1.2	G226K	Pathogenic	0.701
NPC1	O15118-1.2	G226L	Pathogenic	0.789
NPC1	O15118-1.2	G226M	Pathogenic	0.748
NPC1	O15118-1.2	G226N	Neutral	0.493
NPC1	O15118-1.2	G226P	Pathogenic	0.661
NPC1	O15118-1.2	G226Q	Pathogenic	0.727
NPC1	O15118-1.2	G226R	Pathogenic	0.716
NPC1	O15118-1.2	G226S	Pathogenic	0.505
NPC1	O15118-1.2	G226T	Pathogenic	0.699
NPC1	O15118-1.2	G226V	Pathogenic	0.727
NPC1	O15118-1.2	G226W	Pathogenic	0.646
NPC1	O15118-1.2	G226Y	Pathogenic	0.783
NPC1	O15118-1.2	C227A	Pathogenic	0.836
NPC1	O15118-1.2	C227D	Pathogenic	0.912
NPC1	O15118-1.2	C227E	Pathogenic	0.947
NPC1	O15118-1.2	C227F	Pathogenic	0.927
NPC1	O15118-1.2	C227G	Pathogenic	0.943
NPC1	O15118-1.2	C227H	Pathogenic	0.943
NPC1	O15118-1.2	C227I	Pathogenic	0.889
NPC1	O15118-1.2	C227K	Pathogenic	0.927
NPC1	O15118-1.2	C227L	Pathogenic	0.892
NPC1	O15118-1.2	C227M	Pathogenic	0.907
NPC1	O15118-1.2	C227N	Pathogenic	0.919
NPC1	O15118-1.2	C227P	Pathogenic	0.944
NPC1	O15118-1.2	C227Q	Pathogenic	0.935
NPC1	O15118-1.2	C227R	Pathogenic	0.932
NPC1	O15118-1.2	C227S	Pathogenic	0.866
NPC1	O15118-1.2	C227T	Pathogenic	0.873
NPC1	O15118-1.2	C227V	Pathogenic	0.897
NPC1	O15118-1.2	C227W	Pathogenic	0.928
NPC1	O15118-1.2	C227Y	Pathogenic	0.945
NPC1	O15118-1.2	D228A	Pathogenic	0.599
NPC1	O15118-1.2	D228C	Pathogenic	0.61
NPC1	O15118-1.2	D228E	Neutral	0.297
NPC1	O15118-1.2	D228F	Pathogenic	0.603
NPC1	O15118-1.2	D228G	Pathogenic	0.558
NPC1	O15118-1.2	D228H	Pathogenic	0.523
NPC1	O15118-1.2	D228I	Pathogenic	0.585
NPC1	O15118-1.2	D228K	Pathogenic	0.604
NPC1	O15118-1.2	D228L	Pathogenic	0.682
NPC1	O15118-1.2	D228M	Pathogenic	0.631
NPC1	O15118-1.2	D228N	Neutral	0.362
NPC1	O15118-1.2	D228P	Neutral	0.435
NPC1	O15118-1.2	D228Q	Neutral	0.45
NPC1	O15118-1.2	D228R	Pathogenic	0.707
NPC1	O15118-1.2	D228S	Neutral	0.428
NPC1	O15118-1.2	D228T	Neutral	0.475
NPC1	O15118-1.2	D228V	Pathogenic	0.605
NPC1	O15118-1.2	D228W	Pathogenic	0.694
NPC1	O15118-1.2	D228Y	Pathogenic	0.674
NPC1	O15118-1.2	E229A	Pathogenic	0.788
NPC1	O15118-1.2	E229C	Pathogenic	0.894
NPC1	O15118-1.2	E229D	Pathogenic	0.57
NPC1	O15118-1.2	E229F	Pathogenic	0.817
NPC1	O15118-1.2	E229G	Pathogenic	0.872
NPC1	O15118-1.2	E229H	Pathogenic	0.687
NPC1	O15118-1.2	E229I	Pathogenic	0.806
NPC1	O15118-1.2	E229K	Pathogenic	0.656
NPC1	O15118-1.2	E229L	Pathogenic	0.812
NPC1	O15118-1.2	E229M	Pathogenic	0.774
NPC1	O15118-1.2	E229N	Pathogenic	0.742
NPC1	O15118-1.2	E229P	Pathogenic	0.739
NPC1	O15118-1.2	E229Q	Pathogenic	0.527
NPC1	O15118-1.2	E229R	Pathogenic	0.751
NPC1	O15118-1.2	E229S	Pathogenic	0.733
NPC1	O15118-1.2	E229T	Pathogenic	0.764
NPC1	O15118-1.2	E229V	Pathogenic	0.763
NPC1	O15118-1.2	E229W	Pathogenic	0.82
NPC1	O15118-1.2	E229Y	Pathogenic	0.806
NPC1	O15118-1.2	S230A	Neutral	0.278
NPC1	O15118-1.2	S230C	Neutral	0.409
NPC1	O15118-1.2	S230D	Neutral	0.348
NPC1	O15118-1.2	S230E	Neutral	0.383
NPC1	O15118-1.2	S230F	Pathogenic	0.512
NPC1	O15118-1.2	S230G	Neutral	0.412
NPC1	O15118-1.2	S230H	Pathogenic	0.527
NPC1	O15118-1.2	S230I	Neutral	0.494
NPC1	O15118-1.2	S230K	Neutral	0.393
NPC1	O15118-1.2	S230L	Pathogenic	0.502
NPC1	O15118-1.2	S230M	Neutral	0.445
NPC1	O15118-1.2	S230N	Neutral	0.284
NPC1	O15118-1.2	S230P	Neutral	0.437
NPC1	O15118-1.2	S230Q	Neutral	0.424
NPC1	O15118-1.2	S230R	Pathogenic	0.506
NPC1	O15118-1.2	S230T	Neutral	0.298
NPC1	O15118-1.2	S230V	Pathogenic	0.514
NPC1	O15118-1.2	S230W	Pathogenic	0.61
NPC1	O15118-1.2	S230Y	Pathogenic	0.589
NPC1	O15118-1.2	V231A	Neutral	0.233
NPC1	O15118-1.2	V231C	Neutral	0.332
NPC1	O15118-1.2	V231D	Neutral	0.368
NPC1	O15118-1.2	V231E	Neutral	0.281
NPC1	O15118-1.2	V231F	Neutral	0.322
NPC1	O15118-1.2	V231G	Neutral	0.494
NPC1	O15118-1.2	V231H	Neutral	0.439
NPC1	O15118-1.2	V231I	Neutral	0.086
NPC1	O15118-1.2	V231K	Neutral	0.289
NPC1	O15118-1.2	V231L	Neutral	0.175
NPC1	O15118-1.2	V231M	Neutral	0.198
NPC1	O15118-1.2	V231N	Neutral	0.374
NPC1	O15118-1.2	V231P	Neutral	0.396
NPC1	O15118-1.2	V231Q	Neutral	0.316
NPC1	O15118-1.2	V231R	Neutral	0.391
NPC1	O15118-1.2	V231S	Neutral	0.361
NPC1	O15118-1.2	V231T	Neutral	0.203
NPC1	O15118-1.2	V231W	Pathogenic	0.511
NPC1	O15118-1.2	V231Y	Neutral	0.354
NPC1	O15118-1.2	D232A	Pathogenic	0.533
NPC1	O15118-1.2	D232C	Pathogenic	0.545
NPC1	O15118-1.2	D232E	Neutral	0.244
NPC1	O15118-1.2	D232F	Pathogenic	0.537
NPC1	O15118-1.2	D232G	Neutral	0.491
NPC1	O15118-1.2	D232H	Neutral	0.456
NPC1	O15118-1.2	D232I	Pathogenic	0.519
NPC1	O15118-1.2	D232K	Pathogenic	0.538
NPC1	O15118-1.2	D232L	Pathogenic	0.621
NPC1	O15118-1.2	D232M	Pathogenic	0.566
NPC1	O15118-1.2	D232N	Neutral	0.302
NPC1	O15118-1.2	D232P	Neutral	0.371
NPC1	O15118-1.2	D232Q	Neutral	0.385
NPC1	O15118-1.2	D232R	Pathogenic	0.649
NPC1	O15118-1.2	D232S	Neutral	0.363
NPC1	O15118-1.2	D232T	Neutral	0.409
NPC1	O15118-1.2	D232V	Pathogenic	0.539
NPC1	O15118-1.2	D232W	Pathogenic	0.634
NPC1	O15118-1.2	D232Y	Pathogenic	0.613
NPC1	O15118-1.2	E233A	Neutral	0.323
NPC1	O15118-1.2	E233C	Pathogenic	0.519
NPC1	O15118-1.2	E233D	Neutral	0.145
NPC1	O15118-1.2	E233F	Neutral	0.364
NPC1	O15118-1.2	E233G	Neutral	0.465
NPC1	O15118-1.2	E233H	Neutral	0.219
NPC1	O15118-1.2	E233I	Neutral	0.347
NPC1	O15118-1.2	E233K	Neutral	0.196
NPC1	O15118-1.2	E233L	Neutral	0.355
NPC1	O15118-1.2	E233M	Neutral	0.304
NPC1	O15118-1.2	E233N	Neutral	0.269
NPC1	O15118-1.2	E233P	Neutral	0.265
NPC1	O15118-1.2	E233Q	Neutral	0.125
NPC1	O15118-1.2	E233R	Neutral	0.278
NPC1	O15118-1.2	E233S	Neutral	0.259
NPC1	O15118-1.2	E233T	Neutral	0.293
NPC1	O15118-1.2	E233V	Neutral	0.291
NPC1	O15118-1.2	E233W	Neutral	0.367
NPC1	O15118-1.2	E233Y	Neutral	0.347
NPC1	O15118-1.2	V234A	Neutral	0.164
NPC1	O15118-1.2	V234C	Neutral	0.243
NPC1	O15118-1.2	V234D	Neutral	0.273
NPC1	O15118-1.2	V234E	Neutral	0.201
NPC1	O15118-1.2	V234F	Neutral	0.235
NPC1	O15118-1.2	V234G	Neutral	0.387
NPC1	O15118-1.2	V234H	Neutral	0.335
NPC1	O15118-1.2	V234I	Neutral	0.057
NPC1	O15118-1.2	V234K	Neutral	0.208
NPC1	O15118-1.2	V234L	Neutral	0.12
NPC1	O15118-1.2	V234M	Neutral	0.138
NPC1	O15118-1.2	V234N	Neutral	0.278
NPC1	O15118-1.2	V234P	Neutral	0.297
NPC1	O15118-1.2	V234Q	Neutral	0.229
NPC1	O15118-1.2	V234R	Neutral	0.293
NPC1	O15118-1.2	V234S	Neutral	0.267
NPC1	O15118-1.2	V234T	Neutral	0.141
NPC1	O15118-1.2	V234W	Neutral	0.403
NPC1	O15118-1.2	V234Y	Neutral	0.261
NPC1	O15118-1.2	T235A	Pathogenic	0.542
NPC1	O15118-1.2	T235C	Pathogenic	0.554
NPC1	O15118-1.2	T235D	Pathogenic	0.521
NPC1	O15118-1.2	T235E	Pathogenic	0.553
NPC1	O15118-1.2	T235F	Pathogenic	0.633
NPC1	O15118-1.2	T235G	Pathogenic	0.728
NPC1	O15118-1.2	T235H	Pathogenic	0.713
NPC1	O15118-1.2	T235I	Pathogenic	0.522
NPC1	O15118-1.2	T235K	Pathogenic	0.563
NPC1	O15118-1.2	T235L	Pathogenic	0.53
NPC1	O15118-1.2	T235M	Pathogenic	0.569
NPC1	O15118-1.2	T235N	Neutral	0.441
NPC1	O15118-1.2	T235P	Pathogenic	0.569
NPC1	O15118-1.2	T235Q	Pathogenic	0.594
NPC1	O15118-1.2	T235R	Pathogenic	0.581
NPC1	O15118-1.2	T235S	Neutral	0.417
NPC1	O15118-1.2	T235V	Neutral	0.446
NPC1	O15118-1.2	T235W	Pathogenic	0.637
NPC1	O15118-1.2	T235Y	Pathogenic	0.702
NPC1	O15118-1.2	A236C	Neutral	0.177
NPC1	O15118-1.2	A236D	Neutral	0.295
NPC1	O15118-1.2	A236E	Neutral	0.249
NPC1	O15118-1.2	A236F	Neutral	0.323
NPC1	O15118-1.2	A236G	Neutral	0.195
NPC1	O15118-1.2	A236H	Neutral	0.399
NPC1	O15118-1.2	A236I	Neutral	0.232
NPC1	O15118-1.2	A236K	Neutral	0.256
NPC1	O15118-1.2	A236L	Neutral	0.238
NPC1	O15118-1.2	A236M	Neutral	0.268
NPC1	O15118-1.2	A236N	Neutral	0.313
NPC1	O15118-1.2	A236P	Neutral	0.261
NPC1	O15118-1.2	A236Q	Neutral	0.282
NPC1	O15118-1.2	A236R	Neutral	0.271
NPC1	O15118-1.2	A236S	Neutral	0.131
NPC1	O15118-1.2	A236T	Neutral	0.216
NPC1	O15118-1.2	A236V	Neutral	0.182
NPC1	O15118-1.2	A236W	Neutral	0.416
NPC1	O15118-1.2	A236Y	Neutral	0.395
NPC1	O15118-1.2	P237A	Pathogenic	0.731
NPC1	O15118-1.2	P237C	Pathogenic	0.846
NPC1	O15118-1.2	P237D	Pathogenic	0.625
NPC1	O15118-1.2	P237E	Pathogenic	0.66
NPC1	O15118-1.2	P237F	Pathogenic	0.888
NPC1	O15118-1.2	P237G	Pathogenic	0.802
NPC1	O15118-1.2	P237H	Pathogenic	0.796
NPC1	O15118-1.2	P237I	Pathogenic	0.834
NPC1	O15118-1.2	P237K	Pathogenic	0.669
NPC1	O15118-1.2	P237L	Pathogenic	0.839
NPC1	O15118-1.2	P237M	Pathogenic	0.805
NPC1	O15118-1.2	P237N	Pathogenic	0.728
NPC1	O15118-1.2	P237Q	Pathogenic	0.697
NPC1	O15118-1.2	P237R	Pathogenic	0.762
NPC1	O15118-1.2	P237S	Pathogenic	0.701
NPC1	O15118-1.2	P237T	Pathogenic	0.703
NPC1	O15118-1.2	P237V	Pathogenic	0.787
NPC1	O15118-1.2	P237W	Pathogenic	0.89
NPC1	O15118-1.2	P237Y	Pathogenic	0.881
NPC1	O15118-1.2	C238A	Pathogenic	0.836
NPC1	O15118-1.2	C238D	Pathogenic	0.912
NPC1	O15118-1.2	C238E	Pathogenic	0.947
NPC1	O15118-1.2	C238F	Pathogenic	0.927
NPC1	O15118-1.2	C238G	Pathogenic	0.943
NPC1	O15118-1.2	C238H	Pathogenic	0.943
NPC1	O15118-1.2	C238I	Pathogenic	0.889
NPC1	O15118-1.2	C238K	Pathogenic	0.927
NPC1	O15118-1.2	C238L	Pathogenic	0.892
NPC1	O15118-1.2	C238M	Pathogenic	0.907
NPC1	O15118-1.2	C238N	Pathogenic	0.919
NPC1	O15118-1.2	C238P	Pathogenic	0.944
NPC1	O15118-1.2	C238Q	Pathogenic	0.935
NPC1	O15118-1.2	C238R	Pathogenic	0.932
NPC1	O15118-1.2	C238S	Pathogenic	0.866
NPC1	O15118-1.2	C238T	Pathogenic	0.873
NPC1	O15118-1.2	C238V	Pathogenic	0.897
NPC1	O15118-1.2	C238W	Pathogenic	0.928
NPC1	O15118-1.2	C238Y	Pathogenic	0.945
NPC1	O15118-1.2	S239A	Pathogenic	0.865
NPC1	O15118-1.2	S239C	Pathogenic	0.92
NPC1	O15118-1.2	S239D	Pathogenic	0.899
NPC1	O15118-1.2	S239E	Pathogenic	0.912
NPC1	O15118-1.2	S239F	Pathogenic	0.946
NPC1	O15118-1.2	S239G	Pathogenic	0.921
NPC1	O15118-1.2	S239H	Pathogenic	0.949
NPC1	O15118-1.2	S239I	Pathogenic	0.942
NPC1	O15118-1.2	S239K	Pathogenic	0.915
NPC1	O15118-1.2	S239L	Pathogenic	0.944
NPC1	O15118-1.2	S239M	Pathogenic	0.93
NPC1	O15118-1.2	S239N	Pathogenic	0.868
NPC1	O15118-1.2	S239P	Pathogenic	0.928
NPC1	O15118-1.2	S239Q	Pathogenic	0.924
NPC1	O15118-1.2	S239R	Pathogenic	0.945
NPC1	O15118-1.2	S239T	Pathogenic	0.876
NPC1	O15118-1.2	S239V	Pathogenic	0.946
NPC1	O15118-1.2	S239W	Pathogenic	0.963
NPC1	O15118-1.2	S239Y	Pathogenic	0.96
NPC1	O15118-1.2	C240A	Pathogenic	0.836
NPC1	O15118-1.2	C240D	Pathogenic	0.912
NPC1	O15118-1.2	C240E	Pathogenic	0.947
NPC1	O15118-1.2	C240F	Pathogenic	0.927
NPC1	O15118-1.2	C240G	Pathogenic	0.943
NPC1	O15118-1.2	C240H	Pathogenic	0.943
NPC1	O15118-1.2	C240I	Pathogenic	0.889
NPC1	O15118-1.2	C240K	Pathogenic	0.927
NPC1	O15118-1.2	C240L	Pathogenic	0.892
NPC1	O15118-1.2	C240M	Pathogenic	0.907
NPC1	O15118-1.2	C240N	Pathogenic	0.919
NPC1	O15118-1.2	C240P	Pathogenic	0.944
NPC1	O15118-1.2	C240Q	Pathogenic	0.935
NPC1	O15118-1.2	C240R	Pathogenic	0.932
NPC1	O15118-1.2	C240S	Pathogenic	0.866
NPC1	O15118-1.2	C240T	Pathogenic	0.873
NPC1	O15118-1.2	C240V	Pathogenic	0.897
NPC1	O15118-1.2	C240W	Pathogenic	0.928
NPC1	O15118-1.2	C240Y	Pathogenic	0.945
NPC1	O15118-1.2	Q241A	Pathogenic	0.777
NPC1	O15118-1.2	Q241C	Pathogenic	0.843
NPC1	O15118-1.2	Q241D	Pathogenic	0.67
NPC1	O15118-1.2	Q241E	Neutral	0.468
NPC1	O15118-1.2	Q241F	Pathogenic	0.798
NPC1	O15118-1.2	Q241G	Pathogenic	0.864
NPC1	O15118-1.2	Q241H	Pathogenic	0.66
NPC1	O15118-1.2	Q241I	Pathogenic	0.786
NPC1	O15118-1.2	Q241K	Pathogenic	0.56
NPC1	O15118-1.2	Q241L	Pathogenic	0.721
NPC1	O15118-1.2	Q241M	Pathogenic	0.582
NPC1	O15118-1.2	Q241N	Pathogenic	0.676
NPC1	O15118-1.2	Q241P	Pathogenic	0.726
NPC1	O15118-1.2	Q241R	Pathogenic	0.578
NPC1	O15118-1.2	Q241S	Pathogenic	0.719
NPC1	O15118-1.2	Q241T	Pathogenic	0.752
NPC1	O15118-1.2	Q241V	Pathogenic	0.751
NPC1	O15118-1.2	Q241W	Pathogenic	0.731
NPC1	O15118-1.2	Q241Y	Pathogenic	0.713
NPC1	O15118-1.2	D242A	Pathogenic	0.968
NPC1	O15118-1.2	D242C	Pathogenic	0.969
NPC1	O15118-1.2	D242E	Pathogenic	0.894
NPC1	O15118-1.2	D242F	Pathogenic	0.968
NPC1	O15118-1.2	D242G	Pathogenic	0.962
NPC1	O15118-1.2	D242H	Pathogenic	0.956
NPC1	O15118-1.2	D242I	Pathogenic	0.966
NPC1	O15118-1.2	D242K	Pathogenic	0.968
NPC1	O15118-1.2	D242L	Pathogenic	0.977
NPC1	O15118-1.2	D242M	Pathogenic	0.972
NPC1	O15118-1.2	D242N	Pathogenic	0.919
NPC1	O15118-1.2	D242P	Pathogenic	0.939
NPC1	O15118-1.2	D242Q	Pathogenic	0.942
NPC1	O15118-1.2	D242R	Pathogenic	0.98
NPC1	O15118-1.2	D242S	Pathogenic	0.937
NPC1	O15118-1.2	D242T	Pathogenic	0.948
NPC1	O15118-1.2	D242V	Pathogenic	0.968
NPC1	O15118-1.2	D242W	Pathogenic	0.978
NPC1	O15118-1.2	D242Y	Pathogenic	0.976
NPC1	O15118-1.2	C243A	Pathogenic	0.833
NPC1	O15118-1.2	C243D	Pathogenic	0.911
NPC1	O15118-1.2	C243E	Pathogenic	0.946
NPC1	O15118-1.2	C243F	Pathogenic	0.925
NPC1	O15118-1.2	C243G	Pathogenic	0.942
NPC1	O15118-1.2	C243H	Pathogenic	0.942
NPC1	O15118-1.2	C243I	Pathogenic	0.887
NPC1	O15118-1.2	C243K	Pathogenic	0.925
NPC1	O15118-1.2	C243L	Pathogenic	0.89
NPC1	O15118-1.2	C243M	Pathogenic	0.905
NPC1	O15118-1.2	C243N	Pathogenic	0.918
NPC1	O15118-1.2	C243P	Pathogenic	0.943
NPC1	O15118-1.2	C243Q	Pathogenic	0.934
NPC1	O15118-1.2	C243R	Pathogenic	0.93
NPC1	O15118-1.2	C243S	Pathogenic	0.863
NPC1	O15118-1.2	C243T	Pathogenic	0.87
NPC1	O15118-1.2	C243V	Pathogenic	0.895
NPC1	O15118-1.2	C243W	Pathogenic	0.926
NPC1	O15118-1.2	C243Y	Pathogenic	0.943
NPC1	O15118-1.2	S244A	Neutral	0.229
NPC1	O15118-1.2	S244C	Neutral	0.348
NPC1	O15118-1.2	S244D	Neutral	0.292
NPC1	O15118-1.2	S244E	Neutral	0.324
NPC1	O15118-1.2	S244F	Neutral	0.447
NPC1	O15118-1.2	S244G	Neutral	0.351
NPC1	O15118-1.2	S244H	Neutral	0.463
NPC1	O15118-1.2	S244I	Neutral	0.43
NPC1	O15118-1.2	S244K	Neutral	0.333
NPC1	O15118-1.2	S244L	Neutral	0.438
NPC1	O15118-1.2	S244M	Neutral	0.382
NPC1	O15118-1.2	S244N	Neutral	0.234
NPC1	O15118-1.2	S244P	Neutral	0.374
NPC1	O15118-1.2	S244Q	Neutral	0.362
NPC1	O15118-1.2	S244R	Neutral	0.442
NPC1	O15118-1.2	S244T	Neutral	0.247
NPC1	O15118-1.2	S244V	Neutral	0.449
NPC1	O15118-1.2	S244W	Pathogenic	0.547
NPC1	O15118-1.2	S244Y	Pathogenic	0.525
NPC1	O15118-1.2	I245A	Neutral	0.196
NPC1	O15118-1.2	I245C	Neutral	0.213
NPC1	O15118-1.2	I245D	Neutral	0.241
NPC1	O15118-1.2	I245E	Neutral	0.23
NPC1	O15118-1.2	I245F	Neutral	0.17
NPC1	O15118-1.2	I245G	Neutral	0.439
NPC1	O15118-1.2	I245H	Neutral	0.267
NPC1	O15118-1.2	I245K	Neutral	0.206
NPC1	O15118-1.2	I245L	Neutral	0.079
NPC1	O15118-1.2	I245M	Neutral	0.098
NPC1	O15118-1.2	I245N	Neutral	0.246
NPC1	O15118-1.2	I245P	Neutral	0.344
NPC1	O15118-1.2	I245Q	Neutral	0.249
NPC1	O15118-1.2	I245R	Neutral	0.218
NPC1	O15118-1.2	I245S	Neutral	0.235
NPC1	O15118-1.2	I245T	Neutral	0.17
NPC1	O15118-1.2	I245V	Neutral	0.053
NPC1	O15118-1.2	I245W	Neutral	0.401
NPC1	O15118-1.2	I245Y	Neutral	0.192
NPC1	O15118-1.2	V246A	Pathogenic	0.554
NPC1	O15118-1.2	V246C	Pathogenic	0.671
NPC1	O15118-1.2	V246D	Pathogenic	0.705
NPC1	O15118-1.2	V246E	Pathogenic	0.615
NPC1	O15118-1.2	V246F	Pathogenic	0.661
NPC1	O15118-1.2	V246G	Pathogenic	0.8
NPC1	O15118-1.2	V246H	Pathogenic	0.762
NPC1	O15118-1.2	V246I	Neutral	0.279
NPC1	O15118-1.2	V246K	Pathogenic	0.625
NPC1	O15118-1.2	V246L	Neutral	0.464
NPC1	O15118-1.2	V246M	Pathogenic	0.503
NPC1	O15118-1.2	V246N	Pathogenic	0.71
NPC1	O15118-1.2	V246P	Pathogenic	0.728
NPC1	O15118-1.2	V246Q	Pathogenic	0.654
NPC1	O15118-1.2	V246R	Pathogenic	0.725
NPC1	O15118-1.2	V246S	Pathogenic	0.698
NPC1	O15118-1.2	V246T	Pathogenic	0.511
NPC1	O15118-1.2	V246W	Pathogenic	0.811
NPC1	O15118-1.2	V246Y	Pathogenic	0.692
NPC1	O15118-1.2	C247A	Pathogenic	0.836
NPC1	O15118-1.2	C247D	Pathogenic	0.912
NPC1	O15118-1.2	C247E	Pathogenic	0.947
NPC1	O15118-1.2	C247F	Pathogenic	0.927
NPC1	O15118-1.2	C247G	Pathogenic	0.943
NPC1	O15118-1.2	C247H	Pathogenic	0.943
NPC1	O15118-1.2	C247I	Pathogenic	0.889
NPC1	O15118-1.2	C247K	Pathogenic	0.927
NPC1	O15118-1.2	C247L	Pathogenic	0.892
NPC1	O15118-1.2	C247M	Pathogenic	0.907
NPC1	O15118-1.2	C247N	Pathogenic	0.919
NPC1	O15118-1.2	C247P	Pathogenic	0.944
NPC1	O15118-1.2	C247Q	Pathogenic	0.935
NPC1	O15118-1.2	C247R	Pathogenic	0.932
NPC1	O15118-1.2	C247S	Pathogenic	0.866
NPC1	O15118-1.2	C247T	Pathogenic	0.873
NPC1	O15118-1.2	C247V	Pathogenic	0.897
NPC1	O15118-1.2	C247W	Pathogenic	0.928
NPC1	O15118-1.2	C247Y	Pathogenic	0.945
NPC1	O15118-1.2	G248A	Pathogenic	0.65
NPC1	O15118-1.2	G248C	Pathogenic	0.841
NPC1	O15118-1.2	G248D	Pathogenic	0.73
NPC1	O15118-1.2	G248E	Pathogenic	0.823
NPC1	O15118-1.2	G248F	Pathogenic	0.845
NPC1	O15118-1.2	G248H	Pathogenic	0.853
NPC1	O15118-1.2	G248I	Pathogenic	0.882
NPC1	O15118-1.2	G248K	Pathogenic	0.828
NPC1	O15118-1.2	G248L	Pathogenic	0.885
NPC1	O15118-1.2	G248M	Pathogenic	0.86
NPC1	O15118-1.2	G248N	Pathogenic	0.667
NPC1	O15118-1.2	G248P	Pathogenic	0.801
NPC1	O15118-1.2	G248Q	Pathogenic	0.846
NPC1	O15118-1.2	G248R	Pathogenic	0.839
NPC1	O15118-1.2	G248S	Pathogenic	0.678
NPC1	O15118-1.2	G248T	Pathogenic	0.827
NPC1	O15118-1.2	G248V	Pathogenic	0.846
NPC1	O15118-1.2	G248W	Pathogenic	0.79
NPC1	O15118-1.2	G248Y	Pathogenic	0.881
NPC1	O15118-1.2	P249A	Pathogenic	0.894
NPC1	O15118-1.2	P249C	Pathogenic	0.945
NPC1	O15118-1.2	P249D	Pathogenic	0.838
NPC1	O15118-1.2	P249E	Pathogenic	0.858
NPC1	O15118-1.2	P249F	Pathogenic	0.961
NPC1	O15118-1.2	P249G	Pathogenic	0.927
NPC1	O15118-1.2	P249H	Pathogenic	0.924
NPC1	O15118-1.2	P249I	Pathogenic	0.94
NPC1	O15118-1.2	P249K	Pathogenic	0.863
NPC1	O15118-1.2	P249L	Pathogenic	0.942
NPC1	O15118-1.2	P249M	Pathogenic	0.928
NPC1	O15118-1.2	P249N	Pathogenic	0.893
NPC1	O15118-1.2	P249Q	Pathogenic	0.877
NPC1	O15118-1.2	P249R	Pathogenic	0.909
NPC1	O15118-1.2	P249S	Pathogenic	0.879
NPC1	O15118-1.2	P249T	Pathogenic	0.881
NPC1	O15118-1.2	P249V	Pathogenic	0.92
NPC1	O15118-1.2	P249W	Pathogenic	0.962
NPC1	O15118-1.2	P249Y	Pathogenic	0.958
NPC1	O15118-1.2	K250A	Neutral	0.451
NPC1	O15118-1.2	K250C	Pathogenic	0.559
NPC1	O15118-1.2	K250D	Pathogenic	0.504
NPC1	O15118-1.2	K250E	Neutral	0.288
NPC1	O15118-1.2	K250F	Neutral	0.419
NPC1	O15118-1.2	K250G	Pathogenic	0.601
NPC1	O15118-1.2	K250H	Neutral	0.391
NPC1	O15118-1.2	K250I	Neutral	0.434
NPC1	O15118-1.2	K250L	Neutral	0.35
NPC1	O15118-1.2	K250M	Neutral	0.3
NPC1	O15118-1.2	K250N	Neutral	0.388
NPC1	O15118-1.2	K250P	Neutral	0.384
NPC1	O15118-1.2	K250Q	Neutral	0.254
NPC1	O15118-1.2	K250R	Neutral	0.221
NPC1	O15118-1.2	K250S	Neutral	0.377
NPC1	O15118-1.2	K250T	Neutral	0.417
NPC1	O15118-1.2	K250V	Neutral	0.415
NPC1	O15118-1.2	K250W	Neutral	0.423
NPC1	O15118-1.2	K250Y	Neutral	0.401
NPC1	O15118-1.2	P251A	Pathogenic	0.947
NPC1	O15118-1.2	P251C	Pathogenic	0.973
NPC1	O15118-1.2	P251D	Pathogenic	0.916
NPC1	O15118-1.2	P251E	Pathogenic	0.927
NPC1	O15118-1.2	P251F	Pathogenic	0.981
NPC1	O15118-1.2	P251G	Pathogenic	0.964
NPC1	O15118-1.2	P251H	Pathogenic	0.962
NPC1	O15118-1.2	P251I	Pathogenic	0.97
NPC1	O15118-1.2	P251K	Pathogenic	0.929
NPC1	O15118-1.2	P251L	Pathogenic	0.971
NPC1	O15118-1.2	P251M	Pathogenic	0.964
NPC1	O15118-1.2	P251N	Pathogenic	0.946
NPC1	O15118-1.2	P251Q	Pathogenic	0.937
NPC1	O15118-1.2	P251R	Pathogenic	0.954
NPC1	O15118-1.2	P251S	Pathogenic	0.938
NPC1	O15118-1.2	P251T	Pathogenic	0.939
NPC1	O15118-1.2	P251V	Pathogenic	0.96
NPC1	O15118-1.2	P251W	Pathogenic	0.981
NPC1	O15118-1.2	P251Y	Pathogenic	0.98
NPC1	O15118-1.2	Q252A	Neutral	0.453
NPC1	O15118-1.2	Q252C	Pathogenic	0.561
NPC1	O15118-1.2	Q252D	Neutral	0.326
NPC1	O15118-1.2	Q252E	Neutral	0.173
NPC1	O15118-1.2	Q252F	Neutral	0.483
NPC1	O15118-1.2	Q252G	Pathogenic	0.602
NPC1	O15118-1.2	Q252H	Neutral	0.315
NPC1	O15118-1.2	Q252I	Neutral	0.466
NPC1	O15118-1.2	Q252K	Neutral	0.232
NPC1	O15118-1.2	Q252L	Neutral	0.38
NPC1	O15118-1.2	Q252M	Neutral	0.249
NPC1	O15118-1.2	Q252N	Neutral	0.332
NPC1	O15118-1.2	Q252P	Neutral	0.386
NPC1	O15118-1.2	Q252R	Neutral	0.245
NPC1	O15118-1.2	Q252S	Neutral	0.378
NPC1	O15118-1.2	Q252T	Neutral	0.418
NPC1	O15118-1.2	Q252V	Neutral	0.417
NPC1	O15118-1.2	Q252W	Neutral	0.393
NPC1	O15118-1.2	Q252Y	Neutral	0.371
NPC1	O15118-1.2	P253A	Pathogenic	0.927
NPC1	O15118-1.2	P253C	Pathogenic	0.962
NPC1	O15118-1.2	P253D	Pathogenic	0.885
NPC1	O15118-1.2	P253E	Pathogenic	0.9
NPC1	O15118-1.2	P253F	Pathogenic	0.974
NPC1	O15118-1.2	P253G	Pathogenic	0.949
NPC1	O15118-1.2	P253H	Pathogenic	0.947
NPC1	O15118-1.2	P253I	Pathogenic	0.959
NPC1	O15118-1.2	P253K	Pathogenic	0.903
NPC1	O15118-1.2	P253L	Pathogenic	0.96
NPC1	O15118-1.2	P253M	Pathogenic	0.95
NPC1	O15118-1.2	P253N	Pathogenic	0.925
NPC1	O15118-1.2	P253Q	Pathogenic	0.914
NPC1	O15118-1.2	P253R	Pathogenic	0.937
NPC1	O15118-1.2	P253S	Pathogenic	0.916
NPC1	O15118-1.2	P253T	Pathogenic	0.917
NPC1	O15118-1.2	P253V	Pathogenic	0.945
NPC1	O15118-1.2	P253W	Pathogenic	0.974
NPC1	O15118-1.2	P253Y	Pathogenic	0.972
NPC1	O15118-1.2	P254A	Pathogenic	0.83
NPC1	O15118-1.2	P254C	Pathogenic	0.908
NPC1	O15118-1.2	P254D	Pathogenic	0.749
NPC1	O15118-1.2	P254E	Pathogenic	0.777
NPC1	O15118-1.2	P254F	Pathogenic	0.934
NPC1	O15118-1.2	P254G	Pathogenic	0.879
NPC1	O15118-1.2	P254H	Pathogenic	0.875
NPC1	O15118-1.2	P254I	Pathogenic	0.9
NPC1	O15118-1.2	P254K	Pathogenic	0.784
NPC1	O15118-1.2	P254L	Pathogenic	0.903
NPC1	O15118-1.2	P254M	Pathogenic	0.881
NPC1	O15118-1.2	P254N	Pathogenic	0.827
NPC1	O15118-1.2	P254Q	Pathogenic	0.805
NPC1	O15118-1.2	P254R	Pathogenic	0.851
NPC1	O15118-1.2	P254S	Pathogenic	0.808
NPC1	O15118-1.2	P254T	Pathogenic	0.81
NPC1	O15118-1.2	P254V	Pathogenic	0.869
NPC1	O15118-1.2	P254W	Pathogenic	0.935
NPC1	O15118-1.2	P254Y	Pathogenic	0.93
NPC1	O15118-1.2	P255A	Pathogenic	0.838
NPC1	O15118-1.2	P255C	Pathogenic	0.913
NPC1	O15118-1.2	P255D	Pathogenic	0.76
NPC1	O15118-1.2	P255E	Pathogenic	0.787
NPC1	O15118-1.2	P255F	Pathogenic	0.938
NPC1	O15118-1.2	P255G	Pathogenic	0.885
NPC1	O15118-1.2	P255H	Pathogenic	0.881
NPC1	O15118-1.2	P255I	Pathogenic	0.905
NPC1	O15118-1.2	P255K	Pathogenic	0.793
NPC1	O15118-1.2	P255L	Pathogenic	0.908
NPC1	O15118-1.2	P255M	Pathogenic	0.887
NPC1	O15118-1.2	P255N	Pathogenic	0.835
NPC1	O15118-1.2	P255Q	Pathogenic	0.814
NPC1	O15118-1.2	P255R	Pathogenic	0.859
NPC1	O15118-1.2	P255S	Pathogenic	0.816
NPC1	O15118-1.2	P255T	Pathogenic	0.818
NPC1	O15118-1.2	P255V	Pathogenic	0.876
NPC1	O15118-1.2	P255W	Pathogenic	0.939
NPC1	O15118-1.2	P255Y	Pathogenic	0.933
NPC1	O15118-1.2	P256A	Pathogenic	0.65
NPC1	O15118-1.2	P256C	Pathogenic	0.79
NPC1	O15118-1.2	P256D	Pathogenic	0.532
NPC1	O15118-1.2	P256E	Pathogenic	0.569
NPC1	O15118-1.2	P256F	Pathogenic	0.844
NPC1	O15118-1.2	P256G	Pathogenic	0.734
NPC1	O15118-1.2	P256H	Pathogenic	0.726
NPC1	O15118-1.2	P256I	Pathogenic	0.774
NPC1	O15118-1.2	P256K	Pathogenic	0.579
NPC1	O15118-1.2	P256L	Pathogenic	0.78
NPC1	O15118-1.2	P256M	Pathogenic	0.738
NPC1	O15118-1.2	P256N	Pathogenic	0.645
NPC1	O15118-1.2	P256Q	Pathogenic	0.61
NPC1	O15118-1.2	P256R	Pathogenic	0.686
NPC1	O15118-1.2	P256S	Pathogenic	0.615
NPC1	O15118-1.2	P256T	Pathogenic	0.618
NPC1	O15118-1.2	P256V	Pathogenic	0.716
NPC1	O15118-1.2	P256W	Pathogenic	0.846
NPC1	O15118-1.2	P256Y	Pathogenic	0.834
NPC1	O15118-1.2	P257A	Pathogenic	0.859
NPC1	O15118-1.2	P257C	Pathogenic	0.925
NPC1	O15118-1.2	P257D	Pathogenic	0.789
NPC1	O15118-1.2	P257E	Pathogenic	0.813
NPC1	O15118-1.2	P257F	Pathogenic	0.947
NPC1	O15118-1.2	P257G	Pathogenic	0.901
NPC1	O15118-1.2	P257H	Pathogenic	0.897
NPC1	O15118-1.2	P257I	Pathogenic	0.919
NPC1	O15118-1.2	P257K	Pathogenic	0.819
NPC1	O15118-1.2	P257L	Pathogenic	0.921
NPC1	O15118-1.2	P257M	Pathogenic	0.903
NPC1	O15118-1.2	P257N	Pathogenic	0.857
NPC1	O15118-1.2	P257Q	Pathogenic	0.838
NPC1	O15118-1.2	P257R	Pathogenic	0.878
NPC1	O15118-1.2	P257S	Pathogenic	0.84
NPC1	O15118-1.2	P257T	Pathogenic	0.842
NPC1	O15118-1.2	P257V	Pathogenic	0.893
NPC1	O15118-1.2	P257W	Pathogenic	0.948
NPC1	O15118-1.2	P257Y	Pathogenic	0.943
NPC1	O15118-1.2	A258C	Neutral	0.117
NPC1	O15118-1.2	A258D	Neutral	0.206
NPC1	O15118-1.2	A258E	Neutral	0.17
NPC1	O15118-1.2	A258F	Neutral	0.228
NPC1	O15118-1.2	A258G	Neutral	0.131
NPC1	O15118-1.2	A258H	Neutral	0.292
NPC1	O15118-1.2	A258I	Neutral	0.158
NPC1	O15118-1.2	A258K	Neutral	0.176
NPC1	O15118-1.2	A258L	Neutral	0.162
NPC1	O15118-1.2	A258M	Neutral	0.185
NPC1	O15118-1.2	A258N	Neutral	0.22
NPC1	O15118-1.2	A258P	Neutral	0.179
NPC1	O15118-1.2	A258Q	Neutral	0.196
NPC1	O15118-1.2	A258R	Neutral	0.187
NPC1	O15118-1.2	A258S	Neutral	0.085
NPC1	O15118-1.2	A258T	Neutral	0.146
NPC1	O15118-1.2	A258V	Neutral	0.121
NPC1	O15118-1.2	A258W	Neutral	0.307
NPC1	O15118-1.2	A258Y	Neutral	0.288
NPC1	O15118-1.2	P259A	Pathogenic	0.893
NPC1	O15118-1.2	P259C	Pathogenic	0.944
NPC1	O15118-1.2	P259D	Pathogenic	0.836
NPC1	O15118-1.2	P259E	Pathogenic	0.856
NPC1	O15118-1.2	P259F	Pathogenic	0.961
NPC1	O15118-1.2	P259G	Pathogenic	0.926
NPC1	O15118-1.2	P259H	Pathogenic	0.923
NPC1	O15118-1.2	P259I	Pathogenic	0.939
NPC1	O15118-1.2	P259K	Pathogenic	0.861
NPC1	O15118-1.2	P259L	Pathogenic	0.941
NPC1	O15118-1.2	P259M	Pathogenic	0.927
NPC1	O15118-1.2	P259N	Pathogenic	0.891
NPC1	O15118-1.2	P259Q	Pathogenic	0.876
NPC1	O15118-1.2	P259R	Pathogenic	0.907
NPC1	O15118-1.2	P259S	Pathogenic	0.878
NPC1	O15118-1.2	P259T	Pathogenic	0.879
NPC1	O15118-1.2	P259V	Pathogenic	0.919
NPC1	O15118-1.2	P259W	Pathogenic	0.961
NPC1	O15118-1.2	P259Y	Pathogenic	0.958
NPC1	O15118-1.2	W260A	Pathogenic	0.909
NPC1	O15118-1.2	W260C	Pathogenic	0.883
NPC1	O15118-1.2	W260D	Pathogenic	0.899
NPC1	O15118-1.2	W260E	Pathogenic	0.85
NPC1	O15118-1.2	W260F	Pathogenic	0.698
NPC1	O15118-1.2	W260G	Pathogenic	0.873
NPC1	O15118-1.2	W260H	Pathogenic	0.825
NPC1	O15118-1.2	W260I	Pathogenic	0.921
NPC1	O15118-1.2	W260K	Pathogenic	0.811
NPC1	O15118-1.2	W260L	Pathogenic	0.884
NPC1	O15118-1.2	W260M	Pathogenic	0.816
NPC1	O15118-1.2	W260N	Pathogenic	0.901
NPC1	O15118-1.2	W260P	Pathogenic	0.936
NPC1	O15118-1.2	W260Q	Pathogenic	0.811
NPC1	O15118-1.2	W260R	Pathogenic	0.798
NPC1	O15118-1.2	W260S	Pathogenic	0.896
NPC1	O15118-1.2	W260T	Pathogenic	0.851
NPC1	O15118-1.2	W260V	Pathogenic	0.915
NPC1	O15118-1.2	W260Y	Pathogenic	0.535
NPC1	O15118-1.2	T261A	Neutral	0.268
NPC1	O15118-1.2	T261C	Neutral	0.277
NPC1	O15118-1.2	T261D	Neutral	0.252
NPC1	O15118-1.2	T261E	Neutral	0.276
NPC1	O15118-1.2	T261F	Neutral	0.347
NPC1	O15118-1.2	T261G	Neutral	0.453
NPC1	O15118-1.2	T261H	Neutral	0.434
NPC1	O15118-1.2	T261I	Neutral	0.252
NPC1	O15118-1.2	T261K	Neutral	0.285
NPC1	O15118-1.2	T261L	Neutral	0.258
NPC1	O15118-1.2	T261M	Neutral	0.289
NPC1	O15118-1.2	T261N	Neutral	0.196
NPC1	O15118-1.2	T261P	Neutral	0.29
NPC1	O15118-1.2	T261Q	Neutral	0.312
NPC1	O15118-1.2	T261R	Neutral	0.3
NPC1	O15118-1.2	T261S	Neutral	0.181
NPC1	O15118-1.2	T261V	Neutral	0.199
NPC1	O15118-1.2	T261W	Neutral	0.351
NPC1	O15118-1.2	T261Y	Neutral	0.421
NPC1	O15118-1.2	I262A	Pathogenic	0.837
NPC1	O15118-1.2	I262C	Pathogenic	0.851
NPC1	O15118-1.2	I262D	Pathogenic	0.87
NPC1	O15118-1.2	I262E	Pathogenic	0.863
NPC1	O15118-1.2	I262F	Pathogenic	0.812
NPC1	O15118-1.2	I262G	Pathogenic	0.943
NPC1	O15118-1.2	I262H	Pathogenic	0.885
NPC1	O15118-1.2	I262K	Pathogenic	0.845
NPC1	O15118-1.2	I262L	Pathogenic	0.645
NPC1	O15118-1.2	I262M	Pathogenic	0.696
NPC1	O15118-1.2	I262N	Pathogenic	0.873
NPC1	O15118-1.2	I262P	Pathogenic	0.917
NPC1	O15118-1.2	I262Q	Pathogenic	0.875
NPC1	O15118-1.2	I262R	Pathogenic	0.855
NPC1	O15118-1.2	I262S	Pathogenic	0.867
NPC1	O15118-1.2	I262T	Pathogenic	0.812
NPC1	O15118-1.2	I262V	Pathogenic	0.541
NPC1	O15118-1.2	I262W	Pathogenic	0.934
NPC1	O15118-1.2	I262Y	Pathogenic	0.834
NPC1	O15118-1.2	L263A	Neutral	0.352
NPC1	O15118-1.2	L263C	Neutral	0.378
NPC1	O15118-1.2	L263D	Pathogenic	0.511
NPC1	O15118-1.2	L263E	Neutral	0.4
NPC1	O15118-1.2	L263F	Neutral	0.302
NPC1	O15118-1.2	L263G	Pathogenic	0.637
NPC1	O15118-1.2	L263H	Neutral	0.449
NPC1	O15118-1.2	L263I	Neutral	0.157
NPC1	O15118-1.2	L263K	Neutral	0.282
NPC1	O15118-1.2	L263M	Neutral	0.141
NPC1	O15118-1.2	L263N	Neutral	0.422
NPC1	O15118-1.2	L263P	Pathogenic	0.54
NPC1	O15118-1.2	L263Q	Neutral	0.336
NPC1	O15118-1.2	L263R	Neutral	0.298
NPC1	O15118-1.2	L263S	Neutral	0.408
NPC1	O15118-1.2	L263T	Neutral	0.314
NPC1	O15118-1.2	L263V	Neutral	0.213
NPC1	O15118-1.2	L263W	Neutral	0.487
NPC1	O15118-1.2	L263Y	Neutral	0.347
NPC1	O15118-1.2	G264A	Pathogenic	0.859
NPC1	O15118-1.2	G264C	Pathogenic	0.946
NPC1	O15118-1.2	G264D	Pathogenic	0.899
NPC1	O15118-1.2	G264E	Pathogenic	0.938
NPC1	O15118-1.2	G264F	Pathogenic	0.947
NPC1	O15118-1.2	G264H	Pathogenic	0.95
NPC1	O15118-1.2	G264I	Pathogenic	0.961
NPC1	O15118-1.2	G264K	Pathogenic	0.941
NPC1	O15118-1.2	G264L	Pathogenic	0.962
NPC1	O15118-1.2	G264M	Pathogenic	0.953
NPC1	O15118-1.2	G264N	Pathogenic	0.868
NPC1	O15118-1.2	G264P	Pathogenic	0.93
NPC1	O15118-1.2	G264Q	Pathogenic	0.948
NPC1	O15118-1.2	G264R	Pathogenic	0.945
NPC1	O15118-1.2	G264S	Pathogenic	0.874
NPC1	O15118-1.2	G264T	Pathogenic	0.94
NPC1	O15118-1.2	G264V	Pathogenic	0.948
NPC1	O15118-1.2	G264W	Pathogenic	0.925
NPC1	O15118-1.2	G264Y	Pathogenic	0.961
NPC1	O15118-1.2	L265A	Neutral	0.498
NPC1	O15118-1.2	L265C	Pathogenic	0.525
NPC1	O15118-1.2	L265D	Pathogenic	0.656
NPC1	O15118-1.2	L265E	Pathogenic	0.549
NPC1	O15118-1.2	L265F	Neutral	0.441
NPC1	O15118-1.2	L265G	Pathogenic	0.762
NPC1	O15118-1.2	L265H	Pathogenic	0.598
NPC1	O15118-1.2	L265I	Neutral	0.253
NPC1	O15118-1.2	L265K	Neutral	0.418
NPC1	O15118-1.2	L265M	Neutral	0.231
NPC1	O15118-1.2	L265N	Pathogenic	0.571
NPC1	O15118-1.2	L265P	Pathogenic	0.682
NPC1	O15118-1.2	L265Q	Neutral	0.48
NPC1	O15118-1.2	L265R	Neutral	0.436
NPC1	O15118-1.2	L265S	Pathogenic	0.557
NPC1	O15118-1.2	L265T	Neutral	0.455
NPC1	O15118-1.2	L265V	Neutral	0.33
NPC1	O15118-1.2	L265W	Pathogenic	0.634
NPC1	O15118-1.2	L265Y	Neutral	0.492
NPC1	O15118-1.2	D266A	Pathogenic	0.89
NPC1	O15118-1.2	D266C	Pathogenic	0.895
NPC1	O15118-1.2	D266E	Pathogenic	0.696
NPC1	O15118-1.2	D266F	Pathogenic	0.892
NPC1	O15118-1.2	D266G	Pathogenic	0.873
NPC1	O15118-1.2	D266H	Pathogenic	0.856
NPC1	O15118-1.2	D266I	Pathogenic	0.885
NPC1	O15118-1.2	D266K	Pathogenic	0.892
NPC1	O15118-1.2	D266L	Pathogenic	0.921
NPC1	O15118-1.2	D266M	Pathogenic	0.903
NPC1	O15118-1.2	D266N	Pathogenic	0.755
NPC1	O15118-1.2	D266P	Pathogenic	0.807
NPC1	O15118-1.2	D266Q	Pathogenic	0.816
NPC1	O15118-1.2	D266R	Pathogenic	0.929
NPC1	O15118-1.2	D266S	Pathogenic	0.802
NPC1	O15118-1.2	D266T	Pathogenic	0.831
NPC1	O15118-1.2	D266V	Pathogenic	0.893
NPC1	O15118-1.2	D266W	Pathogenic	0.925
NPC1	O15118-1.2	D266Y	Pathogenic	0.918
NPC1	O15118-1.2	A267C	Pathogenic	0.581
NPC1	O15118-1.2	A267D	Pathogenic	0.73
NPC1	O15118-1.2	A267E	Pathogenic	0.682
NPC1	O15118-1.2	A267F	Pathogenic	0.755
NPC1	O15118-1.2	A267G	Pathogenic	0.611
NPC1	O15118-1.2	A267H	Pathogenic	0.811
NPC1	O15118-1.2	A267I	Pathogenic	0.662
NPC1	O15118-1.2	A267K	Pathogenic	0.691
NPC1	O15118-1.2	A267L	Pathogenic	0.669
NPC1	O15118-1.2	A267M	Pathogenic	0.703
NPC1	O15118-1.2	A267N	Pathogenic	0.747
NPC1	O15118-1.2	A267P	Pathogenic	0.695
NPC1	O15118-1.2	A267Q	Pathogenic	0.717
NPC1	O15118-1.2	A267R	Pathogenic	0.706
NPC1	O15118-1.2	A267S	Neutral	0.493
NPC1	O15118-1.2	A267T	Pathogenic	0.64
NPC1	O15118-1.2	A267V	Pathogenic	0.59
NPC1	O15118-1.2	A267W	Pathogenic	0.822
NPC1	O15118-1.2	A267Y	Pathogenic	0.808
NPC1	O15118-1.2	M268A	Pathogenic	0.591
NPC1	O15118-1.2	M268C	Pathogenic	0.617
NPC1	O15118-1.2	M268D	Pathogenic	0.654
NPC1	O15118-1.2	M268E	Pathogenic	0.546
NPC1	O15118-1.2	M268F	Neutral	0.457
NPC1	O15118-1.2	M268G	Pathogenic	0.76
NPC1	O15118-1.2	M268H	Pathogenic	0.596
NPC1	O15118-1.2	M268I	Neutral	0.347
NPC1	O15118-1.2	M268K	Neutral	0.416
NPC1	O15118-1.2	M268L	Neutral	0.272
NPC1	O15118-1.2	M268N	Pathogenic	0.569
NPC1	O15118-1.2	M268P	Pathogenic	0.68
NPC1	O15118-1.2	M268Q	Neutral	0.383
NPC1	O15118-1.2	M268R	Neutral	0.434
NPC1	O15118-1.2	M268S	Pathogenic	0.554
NPC1	O15118-1.2	M268T	Pathogenic	0.548
NPC1	O15118-1.2	M268V	Neutral	0.418
NPC1	O15118-1.2	M268W	Pathogenic	0.557
NPC1	O15118-1.2	M268Y	Pathogenic	0.585
NPC1	O15118-1.2	Y269A	Pathogenic	0.536
NPC1	O15118-1.2	Y269C	Pathogenic	0.56
NPC1	O15118-1.2	Y269D	Pathogenic	0.507
NPC1	O15118-1.2	Y269E	Neutral	0.396
NPC1	O15118-1.2	Y269F	Neutral	0.095
NPC1	O15118-1.2	Y269G	Pathogenic	0.633
NPC1	O15118-1.2	Y269H	Neutral	0.146
NPC1	O15118-1.2	Y269I	Neutral	0.343
NPC1	O15118-1.2	Y269K	Neutral	0.332
NPC1	O15118-1.2	Y269L	Neutral	0.351
NPC1	O15118-1.2	Y269M	Neutral	0.387
NPC1	O15118-1.2	Y269N	Neutral	0.418
NPC1	O15118-1.2	Y269P	Pathogenic	0.629
NPC1	O15118-1.2	Y269Q	Neutral	0.332
NPC1	O15118-1.2	Y269R	Neutral	0.333
NPC1	O15118-1.2	Y269S	Neutral	0.499
NPC1	O15118-1.2	Y269T	Neutral	0.493
NPC1	O15118-1.2	Y269V	Neutral	0.416
NPC1	O15118-1.2	Y269W	Neutral	0.127
NPC1	O15118-1.2	V270A	Neutral	0.36
NPC1	O15118-1.2	V270C	Neutral	0.48
NPC1	O15118-1.2	V270D	Pathogenic	0.519
NPC1	O15118-1.2	V270E	Neutral	0.419
NPC1	O15118-1.2	V270F	Neutral	0.468
NPC1	O15118-1.2	V270G	Pathogenic	0.644
NPC1	O15118-1.2	V270H	Pathogenic	0.592
NPC1	O15118-1.2	V270I	Neutral	0.149
NPC1	O15118-1.2	V270K	Neutral	0.429
NPC1	O15118-1.2	V270L	Neutral	0.282
NPC1	O15118-1.2	V270M	Neutral	0.314
NPC1	O15118-1.2	V270N	Pathogenic	0.526
NPC1	O15118-1.2	V270P	Pathogenic	0.548
NPC1	O15118-1.2	V270Q	Neutral	0.461
NPC1	O15118-1.2	V270R	Pathogenic	0.544
NPC1	O15118-1.2	V270S	Pathogenic	0.511
NPC1	O15118-1.2	V270T	Neutral	0.321
NPC1	O15118-1.2	V270W	Pathogenic	0.659
NPC1	O15118-1.2	V270Y	Pathogenic	0.503
NPC1	O15118-1.2	I271A	Neutral	0.387
NPC1	O15118-1.2	I271C	Neutral	0.413
NPC1	O15118-1.2	I271D	Neutral	0.452
NPC1	O15118-1.2	I271E	Neutral	0.436
NPC1	O15118-1.2	I271F	Neutral	0.347
NPC1	O15118-1.2	I271G	Pathogenic	0.671
NPC1	O15118-1.2	I271H	Neutral	0.486
NPC1	O15118-1.2	I271K	Neutral	0.402
NPC1	O15118-1.2	I271L	Neutral	0.183
NPC1	O15118-1.2	I271M	Neutral	0.22
NPC1	O15118-1.2	I271N	Neutral	0.459
NPC1	O15118-1.2	I271P	Pathogenic	0.577
NPC1	O15118-1.2	I271Q	Neutral	0.463
NPC1	O15118-1.2	I271R	Neutral	0.42
NPC1	O15118-1.2	I271S	Neutral	0.444
NPC1	O15118-1.2	I271T	Neutral	0.347
NPC1	O15118-1.2	I271V	Neutral	0.127
NPC1	O15118-1.2	I271W	Pathogenic	0.635
NPC1	O15118-1.2	I271Y	Neutral	0.381
NPC1	O15118-1.2	M272A	Pathogenic	0.705
NPC1	O15118-1.2	M272C	Pathogenic	0.727
NPC1	O15118-1.2	M272D	Pathogenic	0.757
NPC1	O15118-1.2	M272E	Pathogenic	0.665
NPC1	O15118-1.2	M272F	Pathogenic	0.581
NPC1	O15118-1.2	M272G	Pathogenic	0.839
NPC1	O15118-1.2	M272H	Pathogenic	0.709
NPC1	O15118-1.2	M272I	Neutral	0.468
NPC1	O15118-1.2	M272K	Pathogenic	0.54
NPC1	O15118-1.2	M272L	Neutral	0.382
NPC1	O15118-1.2	M272N	Pathogenic	0.685
NPC1	O15118-1.2	M272P	Pathogenic	0.778
NPC1	O15118-1.2	M272Q	Pathogenic	0.506
NPC1	O15118-1.2	M272R	Pathogenic	0.558
NPC1	O15118-1.2	M272S	Pathogenic	0.672
NPC1	O15118-1.2	M272T	Pathogenic	0.667
NPC1	O15118-1.2	M272V	Pathogenic	0.543
NPC1	O15118-1.2	M272W	Pathogenic	0.675
NPC1	O15118-1.2	M272Y	Pathogenic	0.7
NPC1	O15118-1.2	W273A	Neutral	0.447
NPC1	O15118-1.2	W273C	Neutral	0.38
NPC1	O15118-1.2	W273D	Neutral	0.419
NPC1	O15118-1.2	W273E	Neutral	0.314
NPC1	O15118-1.2	W273F	Neutral	0.158
NPC1	O15118-1.2	W273G	Neutral	0.358
NPC1	O15118-1.2	W273H	Neutral	0.276
NPC1	O15118-1.2	W273I	Neutral	0.485
NPC1	O15118-1.2	W273K	Neutral	0.259
NPC1	O15118-1.2	W273L	Neutral	0.383
NPC1	O15118-1.2	W273M	Neutral	0.265
NPC1	O15118-1.2	W273N	Neutral	0.425
NPC1	O15118-1.2	W273P	Pathogenic	0.543
NPC1	O15118-1.2	W273Q	Neutral	0.258
NPC1	O15118-1.2	W273R	Neutral	0.243
NPC1	O15118-1.2	W273S	Neutral	0.411
NPC1	O15118-1.2	W273T	Neutral	0.316
NPC1	O15118-1.2	W273V	Neutral	0.465
NPC1	O15118-1.2	W273Y	Neutral	0.085
NPC1	O15118-1.2	I274A	Neutral	0.153
NPC1	O15118-1.2	I274C	Neutral	0.168
NPC1	O15118-1.2	I274D	Neutral	0.191
NPC1	O15118-1.2	I274E	Neutral	0.181
NPC1	O15118-1.2	I274F	Neutral	0.132
NPC1	O15118-1.2	I274G	Neutral	0.368
NPC1	O15118-1.2	I274H	Neutral	0.213
NPC1	O15118-1.2	I274K	Neutral	0.161
NPC1	O15118-1.2	I274L	Neutral	0.06
NPC1	O15118-1.2	I274M	Neutral	0.074
NPC1	O15118-1.2	I274N	Neutral	0.195
NPC1	O15118-1.2	I274P	Neutral	0.281
NPC1	O15118-1.2	I274Q	Neutral	0.198
NPC1	O15118-1.2	I274R	Neutral	0.172
NPC1	O15118-1.2	I274S	Neutral	0.186
NPC1	O15118-1.2	I274T	Neutral	0.132
NPC1	O15118-1.2	I274V	Neutral	0.04
NPC1	O15118-1.2	I274W	Neutral	0.332
NPC1	O15118-1.2	I274Y	Neutral	0.15
NPC1	O15118-1.2	T275A	Neutral	0.151
NPC1	O15118-1.2	T275C	Neutral	0.157
NPC1	O15118-1.2	T275D	Neutral	0.141
NPC1	O15118-1.2	T275E	Neutral	0.157
NPC1	O15118-1.2	T275F	Neutral	0.206
NPC1	O15118-1.2	T275G	Neutral	0.288
NPC1	O15118-1.2	T275H	Neutral	0.272
NPC1	O15118-1.2	T275I	Neutral	0.141
NPC1	O15118-1.2	T275K	Neutral	0.163
NPC1	O15118-1.2	T275L	Neutral	0.145
NPC1	O15118-1.2	T275M	Neutral	0.166
NPC1	O15118-1.2	T275N	Neutral	0.106
NPC1	O15118-1.2	T275P	Neutral	0.166
NPC1	O15118-1.2	T275Q	Neutral	0.181
NPC1	O15118-1.2	T275R	Neutral	0.173
NPC1	O15118-1.2	T275S	Neutral	0.097
NPC1	O15118-1.2	T275V	Neutral	0.108
NPC1	O15118-1.2	T275W	Neutral	0.209
NPC1	O15118-1.2	T275Y	Neutral	0.262
NPC1	O15118-1.2	Y276A	Pathogenic	0.657
NPC1	O15118-1.2	Y276C	Pathogenic	0.678
NPC1	O15118-1.2	Y276D	Pathogenic	0.63
NPC1	O15118-1.2	Y276E	Pathogenic	0.521
NPC1	O15118-1.2	Y276F	Neutral	0.148
NPC1	O15118-1.2	Y276G	Pathogenic	0.741
NPC1	O15118-1.2	Y276H	Neutral	0.221
NPC1	O15118-1.2	Y276I	Neutral	0.464
NPC1	O15118-1.2	Y276K	Neutral	0.452
NPC1	O15118-1.2	Y276L	Neutral	0.473
NPC1	O15118-1.2	Y276M	Pathogenic	0.512
NPC1	O15118-1.2	Y276N	Pathogenic	0.543
NPC1	O15118-1.2	Y276P	Pathogenic	0.738
NPC1	O15118-1.2	Y276Q	Neutral	0.451
NPC1	O15118-1.2	Y276R	Neutral	0.452
NPC1	O15118-1.2	Y276S	Pathogenic	0.622
NPC1	O15118-1.2	Y276T	Pathogenic	0.617
NPC1	O15118-1.2	Y276V	Pathogenic	0.542
NPC1	O15118-1.2	Y276W	Neutral	0.195
NPC1	O15118-1.2	M277A	Neutral	0.177
NPC1	O15118-1.2	M277C	Neutral	0.194
NPC1	O15118-1.2	M277D	Neutral	0.22
NPC1	O15118-1.2	M277E	Neutral	0.152
NPC1	O15118-1.2	M277F	Neutral	0.111
NPC1	O15118-1.2	M277G	Neutral	0.321
NPC1	O15118-1.2	M277H	Neutral	0.18
NPC1	O15118-1.2	M277I	Neutral	0.073
NPC1	O15118-1.2	M277K	Neutral	0.096
NPC1	O15118-1.2	M277L	Neutral	0.053
NPC1	O15118-1.2	M277N	Neutral	0.164
NPC1	O15118-1.2	M277P	Neutral	0.24
NPC1	O15118-1.2	M277Q	Neutral	0.085
NPC1	O15118-1.2	M277R	Neutral	0.102
NPC1	O15118-1.2	M277S	Neutral	0.156
NPC1	O15118-1.2	M277T	Neutral	0.153
NPC1	O15118-1.2	M277V	Neutral	0.097
NPC1	O15118-1.2	M277W	Neutral	0.158
NPC1	O15118-1.2	M277Y	Neutral	0.174
NPC1	O15118-1.2	A278C	Neutral	0.117
NPC1	O15118-1.2	A278D	Neutral	0.205
NPC1	O15118-1.2	A278E	Neutral	0.169
NPC1	O15118-1.2	A278F	Neutral	0.227
NPC1	O15118-1.2	A278G	Neutral	0.13
NPC1	O15118-1.2	A278H	Neutral	0.29
NPC1	O15118-1.2	A278I	Neutral	0.157
NPC1	O15118-1.2	A278K	Neutral	0.175
NPC1	O15118-1.2	A278L	Neutral	0.161
NPC1	O15118-1.2	A278M	Neutral	0.184
NPC1	O15118-1.2	A278N	Neutral	0.219
NPC1	O15118-1.2	A278P	Neutral	0.178
NPC1	O15118-1.2	A278Q	Neutral	0.195
NPC1	O15118-1.2	A278R	Neutral	0.186
NPC1	O15118-1.2	A278S	Neutral	0.085
NPC1	O15118-1.2	A278T	Neutral	0.145
NPC1	O15118-1.2	A278V	Neutral	0.121
NPC1	O15118-1.2	A278W	Neutral	0.305
NPC1	O15118-1.2	A278Y	Neutral	0.286
NPC1	O15118-1.2	F279A	Pathogenic	0.535
NPC1	O15118-1.2	F279C	Pathogenic	0.562
NPC1	O15118-1.2	F279D	Pathogenic	0.506
NPC1	O15118-1.2	F279E	Neutral	0.489
NPC1	O15118-1.2	F279G	Pathogenic	0.631
NPC1	O15118-1.2	F279H	Neutral	0.351
NPC1	O15118-1.2	F279I	Neutral	0.38
NPC1	O15118-1.2	F279K	Neutral	0.421
NPC1	O15118-1.2	F279L	Neutral	0.374
NPC1	O15118-1.2	F279M	Neutral	0.339
NPC1	O15118-1.2	F279N	Pathogenic	0.512
NPC1	O15118-1.2	F279P	Pathogenic	0.713
NPC1	O15118-1.2	F279Q	Pathogenic	0.517
NPC1	O15118-1.2	F279R	Neutral	0.44
NPC1	O15118-1.2	F279S	Neutral	0.497
NPC1	O15118-1.2	F279T	Neutral	0.491
NPC1	O15118-1.2	F279V	Neutral	0.457
NPC1	O15118-1.2	F279W	Neutral	0.285
NPC1	O15118-1.2	F279Y	Neutral	0.125
NPC1	O15118-1.2	L280A	Neutral	0.196
NPC1	O15118-1.2	L280C	Neutral	0.214
NPC1	O15118-1.2	L280D	Neutral	0.319
NPC1	O15118-1.2	L280E	Neutral	0.23
NPC1	O15118-1.2	L280F	Neutral	0.162
NPC1	O15118-1.2	L280G	Neutral	0.44
NPC1	O15118-1.2	L280H	Neutral	0.267
NPC1	O15118-1.2	L280I	Neutral	0.077
NPC1	O15118-1.2	L280K	Neutral	0.15
NPC1	O15118-1.2	L280M	Neutral	0.069
NPC1	O15118-1.2	L280N	Neutral	0.246
NPC1	O15118-1.2	L280P	Neutral	0.344
NPC1	O15118-1.2	L280Q	Neutral	0.184
NPC1	O15118-1.2	L280R	Neutral	0.159
NPC1	O15118-1.2	L280S	Neutral	0.236
NPC1	O15118-1.2	L280T	Neutral	0.17
NPC1	O15118-1.2	L280V	Neutral	0.108
NPC1	O15118-1.2	L280W	Neutral	0.298
NPC1	O15118-1.2	L280Y	Neutral	0.192
NPC1	O15118-1.2	L281A	Neutral	0.132
NPC1	O15118-1.2	L281C	Neutral	0.145
NPC1	O15118-1.2	L281D	Neutral	0.226
NPC1	O15118-1.2	L281E	Neutral	0.157
NPC1	O15118-1.2	L281F	Neutral	0.108
NPC1	O15118-1.2	L281G	Neutral	0.329
NPC1	O15118-1.2	L281H	Neutral	0.185
NPC1	O15118-1.2	L281I	Neutral	0.049
NPC1	O15118-1.2	L281K	Neutral	0.099
NPC1	O15118-1.2	L281M	Neutral	0.044
NPC1	O15118-1.2	L281N	Neutral	0.169
NPC1	O15118-1.2	L281P	Neutral	0.247
NPC1	O15118-1.2	L281Q	Neutral	0.124
NPC1	O15118-1.2	L281R	Neutral	0.106
NPC1	O15118-1.2	L281S	Neutral	0.161
NPC1	O15118-1.2	L281T	Neutral	0.113
NPC1	O15118-1.2	L281V	Neutral	0.07
NPC1	O15118-1.2	L281W	Neutral	0.21
NPC1	O15118-1.2	L281Y	Neutral	0.129
NPC1	O15118-1.2	V282A	Neutral	0.117
NPC1	O15118-1.2	V282C	Neutral	0.179
NPC1	O15118-1.2	V282D	Neutral	0.204
NPC1	O15118-1.2	V282E	Neutral	0.146
NPC1	O15118-1.2	V282F	Neutral	0.172
NPC1	O15118-1.2	V282G	Neutral	0.3
NPC1	O15118-1.2	V282H	Neutral	0.255
NPC1	O15118-1.2	V282I	Neutral	0.04
NPC1	O15118-1.2	V282K	Neutral	0.151
NPC1	O15118-1.2	V282L	Neutral	0.085
NPC1	O15118-1.2	V282M	Neutral	0.098
NPC1	O15118-1.2	V282N	Neutral	0.208
NPC1	O15118-1.2	V282P	Neutral	0.223
NPC1	O15118-1.2	V282Q	Neutral	0.168
NPC1	O15118-1.2	V282R	Neutral	0.22
NPC1	O15118-1.2	V282S	Neutral	0.198
NPC1	O15118-1.2	V282T	Neutral	0.1
NPC1	O15118-1.2	V282W	Neutral	0.314
NPC1	O15118-1.2	V282Y	Neutral	0.193
NPC1	O15118-1.2	F283A	Pathogenic	0.771
NPC1	O15118-1.2	F283C	Pathogenic	0.789
NPC1	O15118-1.2	F283D	Pathogenic	0.749
NPC1	O15118-1.2	F283E	Pathogenic	0.737
NPC1	O15118-1.2	F283G	Pathogenic	0.833
NPC1	O15118-1.2	F283H	Pathogenic	0.613
NPC1	O15118-1.2	F283I	Pathogenic	0.642
NPC1	O15118-1.2	F283K	Pathogenic	0.68
NPC1	O15118-1.2	F283L	Pathogenic	0.636
NPC1	O15118-1.2	F283M	Pathogenic	0.599
NPC1	O15118-1.2	F283N	Pathogenic	0.754
NPC1	O15118-1.2	F283P	Pathogenic	0.879
NPC1	O15118-1.2	F283Q	Pathogenic	0.757
NPC1	O15118-1.2	F283R	Pathogenic	0.696
NPC1	O15118-1.2	F283S	Pathogenic	0.743
NPC1	O15118-1.2	F283T	Pathogenic	0.738
NPC1	O15118-1.2	F283V	Pathogenic	0.711
NPC1	O15118-1.2	F283W	Pathogenic	0.538
NPC1	O15118-1.2	F283Y	Neutral	0.294
NPC1	O15118-1.2	F284A	Neutral	0.283
NPC1	O15118-1.2	F284C	Neutral	0.306
NPC1	O15118-1.2	F284D	Neutral	0.26
NPC1	O15118-1.2	F284E	Neutral	0.248
NPC1	O15118-1.2	F284G	Neutral	0.371
NPC1	O15118-1.2	F284H	Neutral	0.157
NPC1	O15118-1.2	F284I	Neutral	0.174
NPC1	O15118-1.2	F284K	Neutral	0.2
NPC1	O15118-1.2	F284L	Neutral	0.171
NPC1	O15118-1.2	F284M	Neutral	0.15
NPC1	O15118-1.2	F284N	Neutral	0.265
NPC1	O15118-1.2	F284P	Neutral	0.46
NPC1	O15118-1.2	F284Q	Neutral	0.269
NPC1	O15118-1.2	F284R	Neutral	0.212
NPC1	O15118-1.2	F284S	Neutral	0.254
NPC1	O15118-1.2	F284T	Neutral	0.249
NPC1	O15118-1.2	F284V	Neutral	0.224
NPC1	O15118-1.2	F284W	Neutral	0.12
NPC1	O15118-1.2	F284Y	Neutral	0.047
NPC1	O15118-1.2	G285A	Neutral	0.121
NPC1	O15118-1.2	G285C	Neutral	0.281
NPC1	O15118-1.2	G285D	Neutral	0.167
NPC1	O15118-1.2	G285E	Neutral	0.255
NPC1	O15118-1.2	G285F	Neutral	0.287
NPC1	O15118-1.2	G285H	Neutral	0.3
NPC1	O15118-1.2	G285I	Neutral	0.355
NPC1	O15118-1.2	G285K	Neutral	0.263
NPC1	O15118-1.2	G285L	Neutral	0.363
NPC1	O15118-1.2	G285M	Neutral	0.312
NPC1	O15118-1.2	G285N	Neutral	0.129
NPC1	O15118-1.2	G285P	Neutral	0.229
NPC1	O15118-1.2	G285Q	Neutral	0.289
NPC1	O15118-1.2	G285R	Neutral	0.278
NPC1	O15118-1.2	G285S	Neutral	0.135
NPC1	O15118-1.2	G285T	Neutral	0.261
NPC1	O15118-1.2	G285V	Neutral	0.289
NPC1	O15118-1.2	G285W	Neutral	0.218
NPC1	O15118-1.2	G285Y	Neutral	0.355
NPC1	O15118-1.2	A286C	Neutral	0.042
NPC1	O15118-1.2	A286D	Neutral	0.079
NPC1	O15118-1.2	A286E	Neutral	0.064
NPC1	O15118-1.2	A286F	Neutral	0.089
NPC1	O15118-1.2	A286G	Neutral	0.047
NPC1	O15118-1.2	A286H	Neutral	0.12
NPC1	O15118-1.2	A286I	Neutral	0.058
NPC1	O15118-1.2	A286K	Neutral	0.066
NPC1	O15118-1.2	A286L	Neutral	0.06
NPC1	O15118-1.2	A286M	Neutral	0.07
NPC1	O15118-1.2	A286N	Neutral	0.086
NPC1	O15118-1.2	A286P	Neutral	0.067
NPC1	O15118-1.2	A286Q	Neutral	0.074
NPC1	O15118-1.2	A286R	Neutral	0.071
NPC1	O15118-1.2	A286S	Neutral	0.03
NPC1	O15118-1.2	A286T	Neutral	0.053
NPC1	O15118-1.2	A286V	Neutral	0.044
NPC1	O15118-1.2	A286W	Neutral	0.128
NPC1	O15118-1.2	A286Y	Neutral	0.118
NPC1	O15118-1.2	F287A	Neutral	0.125
NPC1	O15118-1.2	F287C	Neutral	0.138
NPC1	O15118-1.2	F287D	Neutral	0.113
NPC1	O15118-1.2	F287E	Neutral	0.106
NPC1	O15118-1.2	F287G	Neutral	0.176
NPC1	O15118-1.2	F287H	Neutral	0.063
NPC1	O15118-1.2	F287I	Neutral	0.071
NPC1	O15118-1.2	F287K	Neutral	0.083
NPC1	O15118-1.2	F287L	Neutral	0.069
NPC1	O15118-1.2	F287M	Neutral	0.06
NPC1	O15118-1.2	F287N	Neutral	0.115
NPC1	O15118-1.2	F287P	Neutral	0.236
NPC1	O15118-1.2	F287Q	Neutral	0.117
NPC1	O15118-1.2	F287R	Neutral	0.089
NPC1	O15118-1.2	F287S	Neutral	0.11
NPC1	O15118-1.2	F287T	Neutral	0.107
NPC1	O15118-1.2	F287V	Neutral	0.095
NPC1	O15118-1.2	F287W	Neutral	0.047
NPC1	O15118-1.2	F287Y	Neutral	0.017
NPC1	O15118-1.2	F288A	Neutral	0.208
NPC1	O15118-1.2	F288C	Neutral	0.227
NPC1	O15118-1.2	F288D	Neutral	0.189
NPC1	O15118-1.2	F288E	Neutral	0.179
NPC1	O15118-1.2	F288G	Neutral	0.281
NPC1	O15118-1.2	F288H	Neutral	0.11
NPC1	O15118-1.2	F288I	Neutral	0.123
NPC1	O15118-1.2	F288K	Neutral	0.143
NPC1	O15118-1.2	F288L	Neutral	0.12
NPC1	O15118-1.2	F288M	Neutral	0.105
NPC1	O15118-1.2	F288N	Neutral	0.193
NPC1	O15118-1.2	F288P	Neutral	0.362
NPC1	O15118-1.2	F288Q	Neutral	0.196
NPC1	O15118-1.2	F288R	Neutral	0.152
NPC1	O15118-1.2	F288S	Neutral	0.184
NPC1	O15118-1.2	F288T	Neutral	0.181
NPC1	O15118-1.2	F288V	Neutral	0.161
NPC1	O15118-1.2	F288W	Neutral	0.083
NPC1	O15118-1.2	F288Y	Neutral	0.032
NPC1	O15118-1.2	A289C	Neutral	0.051
NPC1	O15118-1.2	A289D	Neutral	0.095
NPC1	O15118-1.2	A289E	Neutral	0.077
NPC1	O15118-1.2	A289F	Neutral	0.107
NPC1	O15118-1.2	A289G	Neutral	0.057
NPC1	O15118-1.2	A289H	Neutral	0.143
NPC1	O15118-1.2	A289I	Neutral	0.07
NPC1	O15118-1.2	A289K	Neutral	0.079
NPC1	O15118-1.2	A289L	Neutral	0.073
NPC1	O15118-1.2	A289M	Neutral	0.084
NPC1	O15118-1.2	A289N	Neutral	0.102
NPC1	O15118-1.2	A289P	Neutral	0.081
NPC1	O15118-1.2	A289Q	Neutral	0.089
NPC1	O15118-1.2	A289R	Neutral	0.085
NPC1	O15118-1.2	A289S	Neutral	0.036
NPC1	O15118-1.2	A289T	Neutral	0.064
NPC1	O15118-1.2	A289V	Neutral	0.053
NPC1	O15118-1.2	A289W	Neutral	0.151
NPC1	O15118-1.2	A289Y	Neutral	0.14
NPC1	O15118-1.2	V290A	Neutral	0.072
NPC1	O15118-1.2	V290C	Neutral	0.113
NPC1	O15118-1.2	V290D	Neutral	0.13
NPC1	O15118-1.2	V290E	Neutral	0.091
NPC1	O15118-1.2	V290F	Neutral	0.108
NPC1	O15118-1.2	V290G	Neutral	0.2
NPC1	O15118-1.2	V290H	Neutral	0.167
NPC1	O15118-1.2	V290I	Neutral	0.024
NPC1	O15118-1.2	V290K	Neutral	0.094
NPC1	O15118-1.2	V290L	Neutral	0.051
NPC1	O15118-1.2	V290M	Neutral	0.06
NPC1	O15118-1.2	V290N	Neutral	0.133
NPC1	O15118-1.2	V290P	Neutral	0.143
NPC1	O15118-1.2	V290Q	Neutral	0.106
NPC1	O15118-1.2	V290R	Neutral	0.141
NPC1	O15118-1.2	V290S	Neutral	0.126
NPC1	O15118-1.2	V290T	Neutral	0.061
NPC1	O15118-1.2	V290W	Neutral	0.211
NPC1	O15118-1.2	V290Y	Neutral	0.123
NPC1	O15118-1.2	W291A	Pathogenic	0.771
NPC1	O15118-1.2	W291C	Pathogenic	0.719
NPC1	O15118-1.2	W291D	Pathogenic	0.75
NPC1	O15118-1.2	W291E	Pathogenic	0.656
NPC1	O15118-1.2	W291F	Neutral	0.438
NPC1	O15118-1.2	W291G	Pathogenic	0.699
NPC1	O15118-1.2	W291H	Pathogenic	0.613
NPC1	O15118-1.2	W291I	Pathogenic	0.797
NPC1	O15118-1.2	W291K	Pathogenic	0.592
NPC1	O15118-1.2	W291L	Pathogenic	0.72
NPC1	O15118-1.2	W291M	Pathogenic	0.6
NPC1	O15118-1.2	W291N	Pathogenic	0.754
NPC1	O15118-1.2	W291P	Pathogenic	0.832
NPC1	O15118-1.2	W291Q	Pathogenic	0.591
NPC1	O15118-1.2	W291R	Pathogenic	0.571
NPC1	O15118-1.2	W291S	Pathogenic	0.743
NPC1	O15118-1.2	W291T	Pathogenic	0.658
NPC1	O15118-1.2	W291V	Pathogenic	0.784
NPC1	O15118-1.2	W291Y	Neutral	0.28
NPC1	O15118-1.2	C292A	Pathogenic	0.643
NPC1	O15118-1.2	C292D	Pathogenic	0.786
NPC1	O15118-1.2	C292E	Pathogenic	0.863
NPC1	O15118-1.2	C292F	Pathogenic	0.817
NPC1	O15118-1.2	C292G	Pathogenic	0.853
NPC1	O15118-1.2	C292H	Pathogenic	0.854
NPC1	O15118-1.2	C292I	Pathogenic	0.739
NPC1	O15118-1.2	C292K	Pathogenic	0.817
NPC1	O15118-1.2	C292L	Pathogenic	0.746
NPC1	O15118-1.2	C292M	Pathogenic	0.774
NPC1	O15118-1.2	C292N	Pathogenic	0.801
NPC1	O15118-1.2	C292P	Pathogenic	0.857
NPC1	O15118-1.2	C292Q	Pathogenic	0.836
NPC1	O15118-1.2	C292R	Pathogenic	0.828
NPC1	O15118-1.2	C292S	Pathogenic	0.695
NPC1	O15118-1.2	C292T	Pathogenic	0.708
NPC1	O15118-1.2	C292V	Pathogenic	0.754
NPC1	O15118-1.2	C292W	Pathogenic	0.82
NPC1	O15118-1.2	C292Y	Pathogenic	0.858
NPC1	O15118-1.2	Y293A	Pathogenic	0.507
NPC1	O15118-1.2	Y293C	Pathogenic	0.53
NPC1	O15118-1.2	Y293D	Neutral	0.477
NPC1	O15118-1.2	Y293E	Neutral	0.368
NPC1	O15118-1.2	Y293F	Neutral	0.085
NPC1	O15118-1.2	Y293G	Pathogenic	0.605
NPC1	O15118-1.2	Y293H	Neutral	0.132
NPC1	O15118-1.2	Y293I	Neutral	0.317
NPC1	O15118-1.2	Y293K	Neutral	0.307
NPC1	O15118-1.2	Y293L	Neutral	0.325
NPC1	O15118-1.2	Y293M	Neutral	0.36
NPC1	O15118-1.2	Y293N	Neutral	0.389
NPC1	O15118-1.2	Y293P	Pathogenic	0.601
NPC1	O15118-1.2	Y293Q	Neutral	0.306
NPC1	O15118-1.2	Y293R	Neutral	0.307
NPC1	O15118-1.2	Y293S	Neutral	0.469
NPC1	O15118-1.2	Y293T	Neutral	0.463
NPC1	O15118-1.2	Y293V	Neutral	0.388
NPC1	O15118-1.2	Y293W	Neutral	0.115
NPC1	O15118-1.2	R294A	Pathogenic	0.531
NPC1	O15118-1.2	R294C	Pathogenic	0.635
NPC1	O15118-1.2	R294D	Pathogenic	0.673
NPC1	O15118-1.2	R294E	Neutral	0.449
NPC1	O15118-1.2	R294F	Neutral	0.498
NPC1	O15118-1.2	R294G	Pathogenic	0.674
NPC1	O15118-1.2	R294H	Neutral	0.374
NPC1	O15118-1.2	R294I	Pathogenic	0.513
NPC1	O15118-1.2	R294K	Neutral	0.266
NPC1	O15118-1.2	R294L	Neutral	0.426
NPC1	O15118-1.2	R294M	Neutral	0.371
NPC1	O15118-1.2	R294N	Neutral	0.466
NPC1	O15118-1.2	R294P	Pathogenic	0.558
NPC1	O15118-1.2	R294Q	Neutral	0.319
NPC1	O15118-1.2	R294S	Pathogenic	0.55
NPC1	O15118-1.2	R294T	Neutral	0.496
NPC1	O15118-1.2	R294V	Pathogenic	0.59
NPC1	O15118-1.2	R294W	Neutral	0.462
NPC1	O15118-1.2	R294Y	Neutral	0.461
NPC1	O15118-1.2	K295A	Neutral	0.383
NPC1	O15118-1.2	K295C	Neutral	0.489
NPC1	O15118-1.2	K295D	Neutral	0.434
NPC1	O15118-1.2	K295E	Neutral	0.233
NPC1	O15118-1.2	K295F	Neutral	0.352
NPC1	O15118-1.2	K295G	Pathogenic	0.531
NPC1	O15118-1.2	K295H	Neutral	0.326
NPC1	O15118-1.2	K295I	Neutral	0.366
NPC1	O15118-1.2	K295L	Neutral	0.289
NPC1	O15118-1.2	K295M	Neutral	0.244
NPC1	O15118-1.2	K295N	Neutral	0.324
NPC1	O15118-1.2	K295P	Neutral	0.32
NPC1	O15118-1.2	K295Q	Neutral	0.205
NPC1	O15118-1.2	K295R	Neutral	0.176
NPC1	O15118-1.2	K295S	Neutral	0.313
NPC1	O15118-1.2	K295T	Neutral	0.35
NPC1	O15118-1.2	K295V	Neutral	0.349
NPC1	O15118-1.2	K295W	Neutral	0.356
NPC1	O15118-1.2	K295Y	Neutral	0.335
NPC1	O15118-1.2	R296A	Pathogenic	0.688
NPC1	O15118-1.2	R296C	Pathogenic	0.772
NPC1	O15118-1.2	R296D	Pathogenic	0.8
NPC1	O15118-1.2	R296E	Pathogenic	0.614
NPC1	O15118-1.2	R296F	Pathogenic	0.659
NPC1	O15118-1.2	R296G	Pathogenic	0.801
NPC1	O15118-1.2	R296H	Pathogenic	0.538
NPC1	O15118-1.2	R296I	Pathogenic	0.672
NPC1	O15118-1.2	R296K	Neutral	0.414
NPC1	O15118-1.2	R296L	Pathogenic	0.591
NPC1	O15118-1.2	R296M	Pathogenic	0.534
NPC1	O15118-1.2	R296N	Pathogenic	0.629
NPC1	O15118-1.2	R296P	Pathogenic	0.711
NPC1	O15118-1.2	R296Q	Neutral	0.477
NPC1	O15118-1.2	R296S	Pathogenic	0.704
NPC1	O15118-1.2	R296T	Pathogenic	0.657
NPC1	O15118-1.2	R296V	Pathogenic	0.737
NPC1	O15118-1.2	R296W	Pathogenic	0.626
NPC1	O15118-1.2	R296Y	Pathogenic	0.625
NPC1	O15118-1.2	Y297A	Neutral	0.349
NPC1	O15118-1.2	Y297C	Neutral	0.371
NPC1	O15118-1.2	Y297D	Neutral	0.323
NPC1	O15118-1.2	Y297E	Neutral	0.233
NPC1	O15118-1.2	Y297F	Neutral	0.046
NPC1	O15118-1.2	Y297G	Neutral	0.444
NPC1	O15118-1.2	Y297H	Neutral	0.074
NPC1	O15118-1.2	Y297I	Neutral	0.195
NPC1	O15118-1.2	Y297K	Neutral	0.188
NPC1	O15118-1.2	Y297L	Neutral	0.201
NPC1	O15118-1.2	Y297M	Neutral	0.227
NPC1	O15118-1.2	Y297N	Neutral	0.25
NPC1	O15118-1.2	Y297P	Neutral	0.44
NPC1	O15118-1.2	Y297Q	Neutral	0.187
NPC1	O15118-1.2	Y297R	Neutral	0.188
NPC1	O15118-1.2	Y297S	Neutral	0.316
NPC1	O15118-1.2	Y297T	Neutral	0.311
NPC1	O15118-1.2	Y297V	Neutral	0.249
NPC1	O15118-1.2	Y297W	Neutral	0.063
NPC1	O15118-1.2	F298A	Neutral	0.474
NPC1	O15118-1.2	F298C	Pathogenic	0.501
NPC1	O15118-1.2	F298D	Neutral	0.444
NPC1	O15118-1.2	F298E	Neutral	0.428
NPC1	O15118-1.2	F298G	Pathogenic	0.573
NPC1	O15118-1.2	F298H	Neutral	0.298
NPC1	O15118-1.2	F298I	Neutral	0.324
NPC1	O15118-1.2	F298K	Neutral	0.363
NPC1	O15118-1.2	F298L	Neutral	0.319
NPC1	O15118-1.2	F298M	Neutral	0.286
NPC1	O15118-1.2	F298N	Neutral	0.451
NPC1	O15118-1.2	F298P	Pathogenic	0.66
NPC1	O15118-1.2	F298Q	Neutral	0.455
NPC1	O15118-1.2	F298R	Neutral	0.38
NPC1	O15118-1.2	F298S	Neutral	0.436
NPC1	O15118-1.2	F298T	Neutral	0.43
NPC1	O15118-1.2	F298V	Neutral	0.397
NPC1	O15118-1.2	F298W	Neutral	0.238
NPC1	O15118-1.2	F298Y	Neutral	0.1
NPC1	O15118-1.2	V299A	Neutral	0.414
NPC1	O15118-1.2	V299C	Pathogenic	0.536
NPC1	O15118-1.2	V299D	Pathogenic	0.576
NPC1	O15118-1.2	V299E	Neutral	0.476
NPC1	O15118-1.2	V299F	Pathogenic	0.525
NPC1	O15118-1.2	V299G	Pathogenic	0.694
NPC1	O15118-1.2	V299H	Pathogenic	0.645
NPC1	O15118-1.2	V299I	Neutral	0.18
NPC1	O15118-1.2	V299K	Neutral	0.486
NPC1	O15118-1.2	V299L	Neutral	0.33
NPC1	O15118-1.2	V299M	Neutral	0.365
NPC1	O15118-1.2	V299N	Pathogenic	0.582
NPC1	O15118-1.2	V299P	Pathogenic	0.603
NPC1	O15118-1.2	V299Q	Pathogenic	0.518
NPC1	O15118-1.2	V299R	Pathogenic	0.599
NPC1	O15118-1.2	V299S	Pathogenic	0.567
NPC1	O15118-1.2	V299T	Neutral	0.372
NPC1	O15118-1.2	V299W	Pathogenic	0.708
NPC1	O15118-1.2	V299Y	Pathogenic	0.56
NPC1	O15118-1.2	S300A	Neutral	0.308
NPC1	O15118-1.2	S300C	Neutral	0.445
NPC1	O15118-1.2	S300D	Neutral	0.382
NPC1	O15118-1.2	S300E	Neutral	0.419
NPC1	O15118-1.2	S300F	Pathogenic	0.548
NPC1	O15118-1.2	S300G	Neutral	0.448
NPC1	O15118-1.2	S300H	Pathogenic	0.564
NPC1	O15118-1.2	S300I	Pathogenic	0.531
NPC1	O15118-1.2	S300K	Neutral	0.429
NPC1	O15118-1.2	S300L	Pathogenic	0.539
NPC1	O15118-1.2	S300M	Neutral	0.482
NPC1	O15118-1.2	S300N	Neutral	0.314
NPC1	O15118-1.2	S300P	Neutral	0.473
NPC1	O15118-1.2	S300Q	Neutral	0.46
NPC1	O15118-1.2	S300R	Pathogenic	0.543
NPC1	O15118-1.2	S300T	Neutral	0.33
NPC1	O15118-1.2	S300V	Pathogenic	0.551
NPC1	O15118-1.2	S300W	Pathogenic	0.645
NPC1	O15118-1.2	S300Y	Pathogenic	0.624
NPC1	O15118-1.2	E301A	Pathogenic	0.579
NPC1	O15118-1.2	E301C	Pathogenic	0.757
NPC1	O15118-1.2	E301D	Neutral	0.329
NPC1	O15118-1.2	E301F	Pathogenic	0.623
NPC1	O15118-1.2	E301G	Pathogenic	0.716
NPC1	O15118-1.2	E301H	Neutral	0.448
NPC1	O15118-1.2	E301I	Pathogenic	0.606
NPC1	O15118-1.2	E301K	Neutral	0.413
NPC1	O15118-1.2	E301L	Pathogenic	0.614
NPC1	O15118-1.2	E301M	Pathogenic	0.558
NPC1	O15118-1.2	E301N	Pathogenic	0.515
NPC1	O15118-1.2	E301P	Pathogenic	0.511
NPC1	O15118-1.2	E301Q	Neutral	0.292
NPC1	O15118-1.2	E301R	Pathogenic	0.527
NPC1	O15118-1.2	E301S	Pathogenic	0.503
NPC1	O15118-1.2	E301T	Pathogenic	0.545
NPC1	O15118-1.2	E301V	Pathogenic	0.543
NPC1	O15118-1.2	E301W	Pathogenic	0.627
NPC1	O15118-1.2	E301Y	Pathogenic	0.605
NPC1	O15118-1.2	Y302A	Neutral	0.49
NPC1	O15118-1.2	Y302C	Pathogenic	0.514
NPC1	O15118-1.2	Y302D	Neutral	0.461
NPC1	O15118-1.2	Y302E	Neutral	0.353
NPC1	O15118-1.2	Y302F	Neutral	0.08
NPC1	O15118-1.2	Y302G	Pathogenic	0.589
NPC1	O15118-1.2	Y302H	Neutral	0.125
NPC1	O15118-1.2	Y302I	Neutral	0.303
NPC1	O15118-1.2	Y302K	Neutral	0.293
NPC1	O15118-1.2	Y302L	Neutral	0.31
NPC1	O15118-1.2	Y302M	Neutral	0.344
NPC1	O15118-1.2	Y302N	Neutral	0.374
NPC1	O15118-1.2	Y302P	Pathogenic	0.585
NPC1	O15118-1.2	Y302Q	Neutral	0.292
NPC1	O15118-1.2	Y302R	Neutral	0.293
NPC1	O15118-1.2	Y302S	Neutral	0.453
NPC1	O15118-1.2	Y302T	Neutral	0.447
NPC1	O15118-1.2	Y302V	Neutral	0.372
NPC1	O15118-1.2	Y302W	Neutral	0.108
NPC1	O15118-1.2	T303A	Neutral	0.256
NPC1	O15118-1.2	T303C	Neutral	0.265
NPC1	O15118-1.2	T303D	Neutral	0.241
NPC1	O15118-1.2	T303E	Neutral	0.265
NPC1	O15118-1.2	T303F	Neutral	0.334
NPC1	O15118-1.2	T303G	Neutral	0.439
NPC1	O15118-1.2	T303H	Neutral	0.42
NPC1	O15118-1.2	T303I	Neutral	0.241
NPC1	O15118-1.2	T303K	Neutral	0.273
NPC1	O15118-1.2	T303L	Neutral	0.247
NPC1	O15118-1.2	T303M	Neutral	0.278
NPC1	O15118-1.2	T303N	Neutral	0.187
NPC1	O15118-1.2	T303P	Neutral	0.278
NPC1	O15118-1.2	T303Q	Neutral	0.299
NPC1	O15118-1.2	T303R	Neutral	0.288
NPC1	O15118-1.2	T303S	Neutral	0.173
NPC1	O15118-1.2	T303V	Neutral	0.19
NPC1	O15118-1.2	T303W	Neutral	0.338
NPC1	O15118-1.2	T303Y	Neutral	0.407
NPC1	O15118-1.2	P304A	Pathogenic	0.78
NPC1	O15118-1.2	P304C	Pathogenic	0.878
NPC1	O15118-1.2	P304D	Pathogenic	0.685
NPC1	O15118-1.2	P304E	Pathogenic	0.717
NPC1	O15118-1.2	P304F	Pathogenic	0.912
NPC1	O15118-1.2	P304G	Pathogenic	0.841
NPC1	O15118-1.2	P304H	Pathogenic	0.835
NPC1	O15118-1.2	P304I	Pathogenic	0.868
NPC1	O15118-1.2	P304K	Pathogenic	0.725
NPC1	O15118-1.2	P304L	Pathogenic	0.872
NPC1	O15118-1.2	P304M	Pathogenic	0.844
NPC1	O15118-1.2	P304N	Pathogenic	0.777
NPC1	O15118-1.2	P304Q	Pathogenic	0.75
NPC1	O15118-1.2	P304R	Pathogenic	0.807
NPC1	O15118-1.2	P304S	Pathogenic	0.753
NPC1	O15118-1.2	P304T	Pathogenic	0.756
NPC1	O15118-1.2	P304V	Pathogenic	0.829
NPC1	O15118-1.2	P304W	Pathogenic	0.913
NPC1	O15118-1.2	P304Y	Pathogenic	0.906
NPC1	O15118-1.2	I305A	Pathogenic	0.549
NPC1	O15118-1.2	I305C	Pathogenic	0.576
NPC1	O15118-1.2	I305D	Pathogenic	0.614
NPC1	O15118-1.2	I305E	Pathogenic	0.599
NPC1	O15118-1.2	I305F	Pathogenic	0.506
NPC1	O15118-1.2	I305G	Pathogenic	0.797
NPC1	O15118-1.2	I305H	Pathogenic	0.646
NPC1	O15118-1.2	I305K	Pathogenic	0.564
NPC1	O15118-1.2	I305L	Neutral	0.301
NPC1	O15118-1.2	I305M	Neutral	0.352
NPC1	O15118-1.2	I305N	Pathogenic	0.62
NPC1	O15118-1.2	I305P	Pathogenic	0.724
NPC1	O15118-1.2	I305Q	Pathogenic	0.625
NPC1	O15118-1.2	I305R	Pathogenic	0.583
NPC1	O15118-1.2	I305S	Pathogenic	0.606
NPC1	O15118-1.2	I305T	Pathogenic	0.506
NPC1	O15118-1.2	I305V	Neutral	0.219
NPC1	O15118-1.2	I305W	Pathogenic	0.77
NPC1	O15118-1.2	I305Y	Pathogenic	0.543
NPC1	O15118-1.2	D306A	Pathogenic	0.604
NPC1	O15118-1.2	D306C	Pathogenic	0.615
NPC1	O15118-1.2	D306E	Neutral	0.301
NPC1	O15118-1.2	D306F	Pathogenic	0.608
NPC1	O15118-1.2	D306G	Pathogenic	0.563
NPC1	O15118-1.2	D306H	Pathogenic	0.529
NPC1	O15118-1.2	D306I	Pathogenic	0.591
NPC1	O15118-1.2	D306K	Pathogenic	0.609
NPC1	O15118-1.2	D306L	Pathogenic	0.687
NPC1	O15118-1.2	D306M	Pathogenic	0.636
NPC1	O15118-1.2	D306N	Neutral	0.367
NPC1	O15118-1.2	D306P	Neutral	0.441
NPC1	O15118-1.2	D306Q	Neutral	0.455
NPC1	O15118-1.2	D306R	Pathogenic	0.712
NPC1	O15118-1.2	D306S	Neutral	0.433
NPC1	O15118-1.2	D306T	Neutral	0.48
NPC1	O15118-1.2	D306V	Pathogenic	0.61
NPC1	O15118-1.2	D306W	Pathogenic	0.698
NPC1	O15118-1.2	D306Y	Pathogenic	0.679
NPC1	O15118-1.2	S307A	Neutral	0.246
NPC1	O15118-1.2	S307C	Neutral	0.371
NPC1	O15118-1.2	S307D	Neutral	0.312
NPC1	O15118-1.2	S307E	Neutral	0.346
NPC1	O15118-1.2	S307F	Neutral	0.471
NPC1	O15118-1.2	S307G	Neutral	0.374
NPC1	O15118-1.2	S307H	Neutral	0.487
NPC1	O15118-1.2	S307I	Neutral	0.453
NPC1	O15118-1.2	S307K	Neutral	0.355
NPC1	O15118-1.2	S307L	Neutral	0.462
NPC1	O15118-1.2	S307M	Neutral	0.405
NPC1	O15118-1.2	S307N	Neutral	0.252
NPC1	O15118-1.2	S307P	Neutral	0.397
NPC1	O15118-1.2	S307Q	Neutral	0.385
NPC1	O15118-1.2	S307R	Neutral	0.466
NPC1	O15118-1.2	S307T	Neutral	0.265
NPC1	O15118-1.2	S307V	Neutral	0.473
NPC1	O15118-1.2	S307W	Pathogenic	0.571
NPC1	O15118-1.2	S307Y	Pathogenic	0.549
NPC1	O15118-1.2	N308A	Pathogenic	0.52
NPC1	O15118-1.2	N308C	Pathogenic	0.531
NPC1	O15118-1.2	N308D	Neutral	0.273
NPC1	O15118-1.2	N308E	Neutral	0.378
NPC1	O15118-1.2	N308F	Pathogenic	0.508
NPC1	O15118-1.2	N308G	Neutral	0.383
NPC1	O15118-1.2	N308H	Neutral	0.257
NPC1	O15118-1.2	N308I	Neutral	0.49
NPC1	O15118-1.2	N308K	Neutral	0.387
NPC1	O15118-1.2	N308L	Neutral	0.499
NPC1	O15118-1.2	N308M	Neutral	0.442
NPC1	O15118-1.2	N308P	Neutral	0.451
NPC1	O15118-1.2	N308Q	Neutral	0.358
NPC1	O15118-1.2	N308R	Neutral	0.405
NPC1	O15118-1.2	N308S	Neutral	0.269
NPC1	O15118-1.2	N308T	Neutral	0.303
NPC1	O15118-1.2	N308V	Pathogenic	0.51
NPC1	O15118-1.2	N308W	Pathogenic	0.607
NPC1	O15118-1.2	N308Y	Neutral	0.49
NPC1	O15118-1.2	I309A	Neutral	0.202
NPC1	O15118-1.2	I309C	Neutral	0.221
NPC1	O15118-1.2	I309D	Neutral	0.249
NPC1	O15118-1.2	I309E	Neutral	0.237
NPC1	O15118-1.2	I309F	Neutral	0.176
NPC1	O15118-1.2	I309G	Neutral	0.45
NPC1	O15118-1.2	I309H	Neutral	0.276
NPC1	O15118-1.2	I309K	Neutral	0.213
NPC1	O15118-1.2	I309L	Neutral	0.082
NPC1	O15118-1.2	I309M	Neutral	0.102
NPC1	O15118-1.2	I309N	Neutral	0.254
NPC1	O15118-1.2	I309P	Neutral	0.354
NPC1	O15118-1.2	I309Q	Neutral	0.257
NPC1	O15118-1.2	I309R	Neutral	0.225
NPC1	O15118-1.2	I309S	Neutral	0.243
NPC1	O15118-1.2	I309T	Neutral	0.176
NPC1	O15118-1.2	I309V	Neutral	0.055
NPC1	O15118-1.2	I309W	Neutral	0.411
NPC1	O15118-1.2	I309Y	Neutral	0.198
NPC1	O15118-1.2	A310C	Neutral	0.209
NPC1	O15118-1.2	A310D	Neutral	0.341
NPC1	O15118-1.2	A310E	Neutral	0.29
NPC1	O15118-1.2	A310F	Neutral	0.371
NPC1	O15118-1.2	A310G	Neutral	0.23
NPC1	O15118-1.2	A310H	Neutral	0.451
NPC1	O15118-1.2	A310I	Neutral	0.272
NPC1	O15118-1.2	A310K	Neutral	0.299
NPC1	O15118-1.2	A310L	Neutral	0.278
NPC1	O15118-1.2	A310M	Neutral	0.311
NPC1	O15118-1.2	A310N	Neutral	0.36
NPC1	O15118-1.2	A310P	Neutral	0.303
NPC1	O15118-1.2	A310Q	Neutral	0.326
NPC1	O15118-1.2	A310R	Neutral	0.314
NPC1	O15118-1.2	A310S	Neutral	0.157
NPC1	O15118-1.2	A310T	Neutral	0.254
NPC1	O15118-1.2	A310V	Neutral	0.216
NPC1	O15118-1.2	A310W	Neutral	0.468
NPC1	O15118-1.2	A310Y	Neutral	0.446
NPC1	O15118-1.2	F311A	Neutral	0.368
NPC1	O15118-1.2	F311C	Neutral	0.394
NPC1	O15118-1.2	F311D	Neutral	0.341
NPC1	O15118-1.2	F311E	Neutral	0.327
NPC1	O15118-1.2	F311G	Neutral	0.465
NPC1	O15118-1.2	F311H	Neutral	0.215
NPC1	O15118-1.2	F311I	Neutral	0.237
NPC1	O15118-1.2	F311K	Neutral	0.269
NPC1	O15118-1.2	F311L	Neutral	0.233
NPC1	O15118-1.2	F311M	Neutral	0.206
NPC1	O15118-1.2	F311N	Neutral	0.347
NPC1	O15118-1.2	F311P	Pathogenic	0.557
NPC1	O15118-1.2	F311Q	Neutral	0.351
NPC1	O15118-1.2	F311R	Neutral	0.284
NPC1	O15118-1.2	F311S	Neutral	0.334
NPC1	O15118-1.2	F311T	Neutral	0.329
NPC1	O15118-1.2	F311V	Neutral	0.299
NPC1	O15118-1.2	F311W	Neutral	0.168
NPC1	O15118-1.2	F311Y	Neutral	0.067
NPC1	O15118-1.2	S312A	Neutral	0.268
NPC1	O15118-1.2	S312C	Neutral	0.397
NPC1	O15118-1.2	S312D	Neutral	0.337
NPC1	O15118-1.2	S312E	Neutral	0.372
NPC1	O15118-1.2	S312F	Neutral	0.5
NPC1	O15118-1.2	S312G	Neutral	0.401
NPC1	O15118-1.2	S312H	Pathogenic	0.515
NPC1	O15118-1.2	S312I	Neutral	0.482
NPC1	O15118-1.2	S312K	Neutral	0.381
NPC1	O15118-1.2	S312L	Neutral	0.49
NPC1	O15118-1.2	S312M	Neutral	0.433
NPC1	O15118-1.2	S312N	Neutral	0.274
NPC1	O15118-1.2	S312P	Neutral	0.425
NPC1	O15118-1.2	S312Q	Neutral	0.412
NPC1	O15118-1.2	S312R	Neutral	0.494
NPC1	O15118-1.2	S312T	Neutral	0.288
NPC1	O15118-1.2	S312V	Pathogenic	0.502
NPC1	O15118-1.2	S312W	Pathogenic	0.599
NPC1	O15118-1.2	S312Y	Pathogenic	0.577
NPC1	O15118-1.2	V313A	Neutral	0.18
NPC1	O15118-1.2	V313C	Neutral	0.264
NPC1	O15118-1.2	V313D	Neutral	0.296
NPC1	O15118-1.2	V313E	Neutral	0.22
NPC1	O15118-1.2	V313F	Neutral	0.255
NPC1	O15118-1.2	V313G	Neutral	0.414
NPC1	O15118-1.2	V313H	Neutral	0.361
NPC1	O15118-1.2	V313I	Neutral	0.064
NPC1	O15118-1.2	V313K	Neutral	0.227
NPC1	O15118-1.2	V313L	Neutral	0.133
NPC1	O15118-1.2	V313M	Neutral	0.152
NPC1	O15118-1.2	V313N	Neutral	0.302
NPC1	O15118-1.2	V313P	Neutral	0.321
NPC1	O15118-1.2	V313Q	Neutral	0.25
NPC1	O15118-1.2	V313R	Neutral	0.317
NPC1	O15118-1.2	V313S	Neutral	0.289
NPC1	O15118-1.2	V313T	Neutral	0.155
NPC1	O15118-1.2	V313W	Neutral	0.43
NPC1	O15118-1.2	V313Y	Neutral	0.283
NPC1	O15118-1.2	N314A	Pathogenic	0.547
NPC1	O15118-1.2	N314C	Pathogenic	0.558
NPC1	O15118-1.2	N314D	Neutral	0.295
NPC1	O15118-1.2	N314E	Neutral	0.403
NPC1	O15118-1.2	N314F	Pathogenic	0.535
NPC1	O15118-1.2	N314G	Neutral	0.409
NPC1	O15118-1.2	N314H	Neutral	0.278
NPC1	O15118-1.2	N314I	Pathogenic	0.517
NPC1	O15118-1.2	N314K	Neutral	0.413
NPC1	O15118-1.2	N314L	Pathogenic	0.526
NPC1	O15118-1.2	N314M	Neutral	0.469
NPC1	O15118-1.2	N314P	Neutral	0.478
NPC1	O15118-1.2	N314Q	Neutral	0.383
NPC1	O15118-1.2	N314R	Neutral	0.431
NPC1	O15118-1.2	N314S	Neutral	0.291
NPC1	O15118-1.2	N314T	Neutral	0.326
NPC1	O15118-1.2	N314V	Pathogenic	0.537
NPC1	O15118-1.2	N314W	Pathogenic	0.633
NPC1	O15118-1.2	N314Y	Pathogenic	0.517
NPC1	O15118-1.2	A315C	Neutral	0.088
NPC1	O15118-1.2	A315D	Neutral	0.158
NPC1	O15118-1.2	A315E	Neutral	0.129
NPC1	O15118-1.2	A315F	Neutral	0.176
NPC1	O15118-1.2	A315G	Neutral	0.098
NPC1	O15118-1.2	A315H	Neutral	0.229
NPC1	O15118-1.2	A315I	Neutral	0.119
NPC1	O15118-1.2	A315K	Neutral	0.134
NPC1	O15118-1.2	A315L	Neutral	0.123
NPC1	O15118-1.2	A315M	Neutral	0.141
NPC1	O15118-1.2	A315N	Neutral	0.17
NPC1	O15118-1.2	A315P	Neutral	0.136
NPC1	O15118-1.2	A315Q	Neutral	0.149
NPC1	O15118-1.2	A315R	Neutral	0.143
NPC1	O15118-1.2	A315S	Neutral	0.063
NPC1	O15118-1.2	A315T	Neutral	0.11
NPC1	O15118-1.2	A315V	Neutral	0.091
NPC1	O15118-1.2	A315W	Neutral	0.242
NPC1	O15118-1.2	A315Y	Neutral	0.226
NPC1	O15118-1.2	S316A	Neutral	0.067
NPC1	O15118-1.2	S316C	Neutral	0.114
NPC1	O15118-1.2	S316D	Neutral	0.091
NPC1	O15118-1.2	S316E	Neutral	0.104
NPC1	O15118-1.2	S316F	Neutral	0.164
NPC1	O15118-1.2	S316G	Neutral	0.116
NPC1	O15118-1.2	S316H	Neutral	0.172
NPC1	O15118-1.2	S316I	Neutral	0.154
NPC1	O15118-1.2	S316K	Neutral	0.108
NPC1	O15118-1.2	S316L	Neutral	0.159
NPC1	O15118-1.2	S316M	Neutral	0.13
NPC1	O15118-1.2	S316N	Neutral	0.069
NPC1	O15118-1.2	S316P	Neutral	0.126
NPC1	O15118-1.2	S316Q	Neutral	0.121
NPC1	O15118-1.2	S316R	Neutral	0.161
NPC1	O15118-1.2	S316T	Neutral	0.074
NPC1	O15118-1.2	S316V	Neutral	0.165
NPC1	O15118-1.2	S316W	Neutral	0.226
NPC1	O15118-1.2	S316Y	Neutral	0.211
NPC1	O15118-1.2	D317A	Pathogenic	0.586
NPC1	O15118-1.2	D317C	Pathogenic	0.598
NPC1	O15118-1.2	D317E	Neutral	0.286
NPC1	O15118-1.2	D317F	Pathogenic	0.59
NPC1	O15118-1.2	D317G	Pathogenic	0.545
NPC1	O15118-1.2	D317H	Pathogenic	0.51
NPC1	O15118-1.2	D317I	Pathogenic	0.572
NPC1	O15118-1.2	D317K	Pathogenic	0.591
NPC1	O15118-1.2	D317L	Pathogenic	0.671
NPC1	O15118-1.2	D317M	Pathogenic	0.618
NPC1	O15118-1.2	D317N	Neutral	0.349
NPC1	O15118-1.2	D317P	Neutral	0.422
NPC1	O15118-1.2	D317Q	Neutral	0.437
NPC1	O15118-1.2	D317R	Pathogenic	0.696
NPC1	O15118-1.2	D317S	Neutral	0.415
NPC1	O15118-1.2	D317T	Neutral	0.462
NPC1	O15118-1.2	D317V	Pathogenic	0.592
NPC1	O15118-1.2	D317W	Pathogenic	0.682
NPC1	O15118-1.2	D317Y	Pathogenic	0.663
NPC1	O15118-1.2	K318A	Neutral	0.303
NPC1	O15118-1.2	K318C	Neutral	0.401
NPC1	O15118-1.2	K318D	Neutral	0.35
NPC1	O15118-1.2	K318E	Neutral	0.176
NPC1	O15118-1.2	K318F	Neutral	0.276
NPC1	O15118-1.2	K318G	Neutral	0.443
NPC1	O15118-1.2	K318H	Neutral	0.253
NPC1	O15118-1.2	K318I	Neutral	0.288
NPC1	O15118-1.2	K318L	Neutral	0.222
NPC1	O15118-1.2	K318M	Neutral	0.185
NPC1	O15118-1.2	K318N	Neutral	0.251
NPC1	O15118-1.2	K318P	Neutral	0.248
NPC1	O15118-1.2	K318Q	Neutral	0.153
NPC1	O15118-1.2	K318R	Neutral	0.131
NPC1	O15118-1.2	K318S	Neutral	0.242
NPC1	O15118-1.2	K318T	Neutral	0.274
NPC1	O15118-1.2	K318V	Neutral	0.273
NPC1	O15118-1.2	K318W	Neutral	0.279
NPC1	O15118-1.2	K318Y	Neutral	0.261
NPC1	O15118-1.2	G319A	Neutral	0.491
NPC1	O15118-1.2	G319C	Pathogenic	0.734
NPC1	O15118-1.2	G319D	Pathogenic	0.585
NPC1	O15118-1.2	G319E	Pathogenic	0.707
NPC1	O15118-1.2	G319F	Pathogenic	0.739
NPC1	O15118-1.2	G319H	Pathogenic	0.751
NPC1	O15118-1.2	G319I	Pathogenic	0.795
NPC1	O15118-1.2	G319K	Pathogenic	0.715
NPC1	O15118-1.2	G319L	Pathogenic	0.801
NPC1	O15118-1.2	G319M	Pathogenic	0.761
NPC1	O15118-1.2	G319N	Pathogenic	0.511
NPC1	O15118-1.2	G319P	Pathogenic	0.677
NPC1	O15118-1.2	G319Q	Pathogenic	0.741
NPC1	O15118-1.2	G319R	Pathogenic	0.73
NPC1	O15118-1.2	G319S	Pathogenic	0.523
NPC1	O15118-1.2	G319T	Pathogenic	0.713
NPC1	O15118-1.2	G319V	Pathogenic	0.741
NPC1	O15118-1.2	G319W	Pathogenic	0.662
NPC1	O15118-1.2	G319Y	Pathogenic	0.795
NPC1	O15118-1.2	E320A	Neutral	0.336
NPC1	O15118-1.2	E320C	Pathogenic	0.534
NPC1	O15118-1.2	E320D	Neutral	0.153
NPC1	O15118-1.2	E320F	Neutral	0.378
NPC1	O15118-1.2	E320G	Neutral	0.48
NPC1	O15118-1.2	E320H	Neutral	0.23
NPC1	O15118-1.2	E320I	Neutral	0.361
NPC1	O15118-1.2	E320K	Neutral	0.205
NPC1	O15118-1.2	E320L	Neutral	0.369
NPC1	O15118-1.2	E320M	Neutral	0.317
NPC1	O15118-1.2	E320N	Neutral	0.281
NPC1	O15118-1.2	E320P	Neutral	0.277
NPC1	O15118-1.2	E320Q	Neutral	0.131
NPC1	O15118-1.2	E320R	Neutral	0.29
NPC1	O15118-1.2	E320S	Neutral	0.271
NPC1	O15118-1.2	E320T	Neutral	0.305
NPC1	O15118-1.2	E320V	Neutral	0.304
NPC1	O15118-1.2	E320W	Neutral	0.381
NPC1	O15118-1.2	E320Y	Neutral	0.36
NPC1	O15118-1.2	A321C	Neutral	0.198
NPC1	O15118-1.2	A321D	Neutral	0.325
NPC1	O15118-1.2	A321E	Neutral	0.276
NPC1	O15118-1.2	A321F	Neutral	0.354
NPC1	O15118-1.2	A321G	Neutral	0.218
NPC1	O15118-1.2	A321H	Neutral	0.433
NPC1	O15118-1.2	A321I	Neutral	0.258
NPC1	O15118-1.2	A321K	Neutral	0.284
NPC1	O15118-1.2	A321L	Neutral	0.264
NPC1	O15118-1.2	A321M	Neutral	0.296
NPC1	O15118-1.2	A321N	Neutral	0.344
NPC1	O15118-1.2	A321P	Neutral	0.288
NPC1	O15118-1.2	A321Q	Neutral	0.311
NPC1	O15118-1.2	A321R	Neutral	0.299
NPC1	O15118-1.2	A321S	Neutral	0.147
NPC1	O15118-1.2	A321T	Neutral	0.24
NPC1	O15118-1.2	A321V	Neutral	0.204
NPC1	O15118-1.2	A321W	Neutral	0.45
NPC1	O15118-1.2	A321Y	Neutral	0.428
NPC1	O15118-1.2	S322A	Neutral	0.242
NPC1	O15118-1.2	S322C	Neutral	0.366
NPC1	O15118-1.2	S322D	Neutral	0.308
NPC1	O15118-1.2	S322E	Neutral	0.341
NPC1	O15118-1.2	S322F	Neutral	0.466
NPC1	O15118-1.2	S322G	Neutral	0.369
NPC1	O15118-1.2	S322H	Neutral	0.481
NPC1	O15118-1.2	S322I	Neutral	0.448
NPC1	O15118-1.2	S322K	Neutral	0.35
NPC1	O15118-1.2	S322L	Neutral	0.457
NPC1	O15118-1.2	S322M	Neutral	0.4
NPC1	O15118-1.2	S322N	Neutral	0.248
NPC1	O15118-1.2	S322P	Neutral	0.392
NPC1	O15118-1.2	S322Q	Neutral	0.38
NPC1	O15118-1.2	S322R	Neutral	0.46
NPC1	O15118-1.2	S322T	Neutral	0.261
NPC1	O15118-1.2	S322V	Neutral	0.468
NPC1	O15118-1.2	S322W	Pathogenic	0.566
NPC1	O15118-1.2	S322Y	Pathogenic	0.544
NPC1	O15118-1.2	C323A	Pathogenic	0.509
NPC1	O15118-1.2	C323D	Pathogenic	0.679
NPC1	O15118-1.2	C323E	Pathogenic	0.784
NPC1	O15118-1.2	C323F	Pathogenic	0.72
NPC1	O15118-1.2	C323G	Pathogenic	0.769
NPC1	O15118-1.2	C323H	Pathogenic	0.771
NPC1	O15118-1.2	C323I	Pathogenic	0.619
NPC1	O15118-1.2	C323K	Pathogenic	0.719
NPC1	O15118-1.2	C323L	Pathogenic	0.627
NPC1	O15118-1.2	C323M	Pathogenic	0.663
NPC1	O15118-1.2	C323N	Pathogenic	0.697
NPC1	O15118-1.2	C323P	Pathogenic	0.775
NPC1	O15118-1.2	C323Q	Pathogenic	0.745
NPC1	O15118-1.2	C323R	Pathogenic	0.734
NPC1	O15118-1.2	C323S	Pathogenic	0.567
NPC1	O15118-1.2	C323T	Pathogenic	0.582
NPC1	O15118-1.2	C323V	Pathogenic	0.638
NPC1	O15118-1.2	C323W	Pathogenic	0.723
NPC1	O15118-1.2	C323Y	Pathogenic	0.776
NPC1	O15118-1.2	C324A	Neutral	0.222
NPC1	O15118-1.2	C324D	Neutral	0.369
NPC1	O15118-1.2	C324E	Pathogenic	0.5
NPC1	O15118-1.2	C324F	Neutral	0.415
NPC1	O15118-1.2	C324G	Neutral	0.48
NPC1	O15118-1.2	C324H	Neutral	0.481
NPC1	O15118-1.2	C324I	Neutral	0.31
NPC1	O15118-1.2	C324K	Neutral	0.415
NPC1	O15118-1.2	C324L	Neutral	0.317
NPC1	O15118-1.2	C324M	Neutral	0.352
NPC1	O15118-1.2	C324N	Neutral	0.389
NPC1	O15118-1.2	C324P	Neutral	0.488
NPC1	O15118-1.2	C324Q	Neutral	0.446
NPC1	O15118-1.2	C324R	Neutral	0.433
NPC1	O15118-1.2	C324S	Neutral	0.266
NPC1	O15118-1.2	C324T	Neutral	0.278
NPC1	O15118-1.2	C324V	Neutral	0.327
NPC1	O15118-1.2	C324W	Neutral	0.419
NPC1	O15118-1.2	C324Y	Neutral	0.489
NPC1	O15118-1.2	D325A	Pathogenic	0.764
NPC1	O15118-1.2	D325C	Pathogenic	0.772
NPC1	O15118-1.2	D325E	Neutral	0.477
NPC1	O15118-1.2	D325F	Pathogenic	0.766
NPC1	O15118-1.2	D325G	Pathogenic	0.732
NPC1	O15118-1.2	D325H	Pathogenic	0.703
NPC1	O15118-1.2	D325I	Pathogenic	0.753
NPC1	O15118-1.2	D325K	Pathogenic	0.767
NPC1	O15118-1.2	D325L	Pathogenic	0.823
NPC1	O15118-1.2	D325M	Pathogenic	0.787
NPC1	O15118-1.2	D325N	Pathogenic	0.55
NPC1	O15118-1.2	D325P	Pathogenic	0.625
NPC1	O15118-1.2	D325Q	Pathogenic	0.639
NPC1	O15118-1.2	D325R	Pathogenic	0.839
NPC1	O15118-1.2	D325S	Pathogenic	0.618
NPC1	O15118-1.2	D325T	Pathogenic	0.662
NPC1	O15118-1.2	D325V	Pathogenic	0.768
NPC1	O15118-1.2	D325W	Pathogenic	0.83
NPC1	O15118-1.2	D325Y	Pathogenic	0.817
NPC1	O15118-1.2	P326A	Neutral	0.362
NPC1	O15118-1.2	P326C	Pathogenic	0.535
NPC1	O15118-1.2	P326D	Neutral	0.258
NPC1	O15118-1.2	P326E	Neutral	0.288
NPC1	O15118-1.2	P326F	Pathogenic	0.624
NPC1	O15118-1.2	P326G	Neutral	0.458
NPC1	O15118-1.2	P326H	Neutral	0.448
NPC1	O15118-1.2	P326I	Pathogenic	0.512
NPC1	O15118-1.2	P326K	Neutral	0.297
NPC1	O15118-1.2	P326L	Pathogenic	0.521
NPC1	O15118-1.2	P326M	Neutral	0.463
NPC1	O15118-1.2	P326N	Neutral	0.358
NPC1	O15118-1.2	P326Q	Neutral	0.324
NPC1	O15118-1.2	P326R	Neutral	0.4
NPC1	O15118-1.2	P326S	Neutral	0.328
NPC1	O15118-1.2	P326T	Neutral	0.331
NPC1	O15118-1.2	P326V	Neutral	0.436
NPC1	O15118-1.2	P326W	Pathogenic	0.628
NPC1	O15118-1.2	P326Y	Pathogenic	0.606
NPC1	O15118-1.2	V327A	Neutral	0.218
NPC1	O15118-1.2	V327C	Neutral	0.314
NPC1	O15118-1.2	V327D	Neutral	0.349
NPC1	O15118-1.2	V327E	Neutral	0.264
NPC1	O15118-1.2	V327F	Neutral	0.304
NPC1	O15118-1.2	V327G	Neutral	0.473
NPC1	O15118-1.2	V327H	Neutral	0.419
NPC1	O15118-1.2	V327I	Neutral	0.08
NPC1	O15118-1.2	V327K	Neutral	0.272
NPC1	O15118-1.2	V327L	Neutral	0.163
NPC1	O15118-1.2	V327M	Neutral	0.185
NPC1	O15118-1.2	V327N	Neutral	0.355
NPC1	O15118-1.2	V327P	Neutral	0.376
NPC1	O15118-1.2	V327Q	Neutral	0.298
NPC1	O15118-1.2	V327R	Neutral	0.372
NPC1	O15118-1.2	V327S	Neutral	0.342
NPC1	O15118-1.2	V327T	Neutral	0.19
NPC1	O15118-1.2	V327W	Neutral	0.49
NPC1	O15118-1.2	V327Y	Neutral	0.335
NPC1	O15118-1.2	S328A	Pathogenic	0.581
NPC1	O15118-1.2	S328C	Pathogenic	0.714
NPC1	O15118-1.2	S328D	Pathogenic	0.659
NPC1	O15118-1.2	S328E	Pathogenic	0.692
NPC1	O15118-1.2	S328F	Pathogenic	0.791
NPC1	O15118-1.2	S328G	Pathogenic	0.717
NPC1	O15118-1.2	S328H	Pathogenic	0.801
NPC1	O15118-1.2	S328I	Pathogenic	0.779
NPC1	O15118-1.2	S328K	Pathogenic	0.701
NPC1	O15118-1.2	S328L	Pathogenic	0.785
NPC1	O15118-1.2	S328M	Pathogenic	0.744
NPC1	O15118-1.2	S328N	Pathogenic	0.588
NPC1	O15118-1.2	S328P	Pathogenic	0.737
NPC1	O15118-1.2	S328Q	Pathogenic	0.727
NPC1	O15118-1.2	S328R	Pathogenic	0.787
NPC1	O15118-1.2	S328T	Pathogenic	0.606
NPC1	O15118-1.2	S328V	Pathogenic	0.792
NPC1	O15118-1.2	S328W	Pathogenic	0.85
NPC1	O15118-1.2	S328Y	Pathogenic	0.838
NPC1	O15118-1.2	A329C	Neutral	0.417
NPC1	O15118-1.2	A329D	Pathogenic	0.582
NPC1	O15118-1.2	A329E	Pathogenic	0.525
NPC1	O15118-1.2	A329F	Pathogenic	0.614
NPC1	O15118-1.2	A329G	Neutral	0.447
NPC1	O15118-1.2	A329H	Pathogenic	0.689
NPC1	O15118-1.2	A329I	Pathogenic	0.502
NPC1	O15118-1.2	A329K	Pathogenic	0.535
NPC1	O15118-1.2	A329L	Pathogenic	0.51
NPC1	O15118-1.2	A329M	Pathogenic	0.549
NPC1	O15118-1.2	A329N	Pathogenic	0.603
NPC1	O15118-1.2	A329P	Pathogenic	0.54
NPC1	O15118-1.2	A329Q	Pathogenic	0.567
NPC1	O15118-1.2	A329R	Pathogenic	0.553
NPC1	O15118-1.2	A329S	Neutral	0.334
NPC1	O15118-1.2	A329T	Neutral	0.478
NPC1	O15118-1.2	A329V	Neutral	0.426
NPC1	O15118-1.2	A329W	Pathogenic	0.704
NPC1	O15118-1.2	A329Y	Pathogenic	0.685
NPC1	O15118-1.2	A330C	Neutral	0.162
NPC1	O15118-1.2	A330D	Neutral	0.274
NPC1	O15118-1.2	A330E	Neutral	0.231
NPC1	O15118-1.2	A330F	Neutral	0.302
NPC1	O15118-1.2	A330G	Neutral	0.18
NPC1	O15118-1.2	A330H	Neutral	0.375
NPC1	O15118-1.2	A330I	Neutral	0.215
NPC1	O15118-1.2	A330K	Neutral	0.238
NPC1	O15118-1.2	A330L	Neutral	0.22
NPC1	O15118-1.2	A330M	Neutral	0.248
NPC1	O15118-1.2	A330N	Neutral	0.292
NPC1	O15118-1.2	A330P	Neutral	0.242
NPC1	O15118-1.2	A330Q	Neutral	0.262
NPC1	O15118-1.2	A330R	Neutral	0.251
NPC1	O15118-1.2	A330S	Neutral	0.12
NPC1	O15118-1.2	A330T	Neutral	0.199
NPC1	O15118-1.2	A330V	Neutral	0.168
NPC1	O15118-1.2	A330W	Neutral	0.392
NPC1	O15118-1.2	A330Y	Neutral	0.371
NPC1	O15118-1.2	F331A	Pathogenic	0.612
NPC1	O15118-1.2	F331C	Pathogenic	0.638
NPC1	O15118-1.2	F331D	Pathogenic	0.584
NPC1	O15118-1.2	F331E	Pathogenic	0.568
NPC1	O15118-1.2	F331G	Pathogenic	0.702
NPC1	O15118-1.2	F331H	Neutral	0.427
NPC1	O15118-1.2	F331I	Neutral	0.457
NPC1	O15118-1.2	F331K	Pathogenic	0.5
NPC1	O15118-1.2	F331L	Neutral	0.451
NPC1	O15118-1.2	F331M	Neutral	0.413
NPC1	O15118-1.2	F331N	Pathogenic	0.59
NPC1	O15118-1.2	F331P	Pathogenic	0.773
NPC1	O15118-1.2	F331Q	Pathogenic	0.595
NPC1	O15118-1.2	F331R	Pathogenic	0.518
NPC1	O15118-1.2	F331S	Pathogenic	0.576
NPC1	O15118-1.2	F331T	Pathogenic	0.57
NPC1	O15118-1.2	F331V	Pathogenic	0.536
NPC1	O15118-1.2	F331W	Neutral	0.353
NPC1	O15118-1.2	F331Y	Neutral	0.164
NPC1	O15118-1.2	E332A	Pathogenic	0.839
NPC1	O15118-1.2	E332C	Pathogenic	0.922
NPC1	O15118-1.2	E332D	Pathogenic	0.65
NPC1	O15118-1.2	E332F	Pathogenic	0.862
NPC1	O15118-1.2	E332G	Pathogenic	0.905
NPC1	O15118-1.2	E332H	Pathogenic	0.755
NPC1	O15118-1.2	E332I	Pathogenic	0.854
NPC1	O15118-1.2	E332K	Pathogenic	0.727
NPC1	O15118-1.2	E332L	Pathogenic	0.858
NPC1	O15118-1.2	E332M	Pathogenic	0.828
NPC1	O15118-1.2	E332N	Pathogenic	0.801
NPC1	O15118-1.2	E332P	Pathogenic	0.799
NPC1	O15118-1.2	E332Q	Pathogenic	0.61
NPC1	O15118-1.2	E332R	Pathogenic	0.809
NPC1	O15118-1.2	E332S	Pathogenic	0.793
NPC1	O15118-1.2	E332T	Pathogenic	0.819
NPC1	O15118-1.2	E332V	Pathogenic	0.819
NPC1	O15118-1.2	E332W	Pathogenic	0.864
NPC1	O15118-1.2	E332Y	Pathogenic	0.853
NPC1	O15118-1.2	G333A	Neutral	0.146
NPC1	O15118-1.2	G333C	Neutral	0.329
NPC1	O15118-1.2	G333D	Neutral	0.2
NPC1	O15118-1.2	G333E	Neutral	0.3
NPC1	O15118-1.2	G333F	Neutral	0.335
NPC1	O15118-1.2	G333H	Neutral	0.349
NPC1	O15118-1.2	G333I	Neutral	0.408
NPC1	O15118-1.2	G333K	Neutral	0.309
NPC1	O15118-1.2	G333L	Neutral	0.416
NPC1	O15118-1.2	G333M	Neutral	0.362
NPC1	O15118-1.2	G333N	Neutral	0.156
NPC1	O15118-1.2	G333P	Neutral	0.271
NPC1	O15118-1.2	G333Q	Neutral	0.337
NPC1	O15118-1.2	G333R	Neutral	0.325
NPC1	O15118-1.2	G333S	Neutral	0.163
NPC1	O15118-1.2	G333T	Neutral	0.306
NPC1	O15118-1.2	G333V	Neutral	0.337
NPC1	O15118-1.2	G333W	Neutral	0.258
NPC1	O15118-1.2	G333Y	Neutral	0.407
NPC1	O15118-1.2	C334A	Neutral	0.163
NPC1	O15118-1.2	C334D	Neutral	0.285
NPC1	O15118-1.2	C334E	Neutral	0.406
NPC1	O15118-1.2	C334F	Neutral	0.326
NPC1	O15118-1.2	C334G	Neutral	0.386
NPC1	O15118-1.2	C334H	Neutral	0.387
NPC1	O15118-1.2	C334I	Neutral	0.234
NPC1	O15118-1.2	C334K	Neutral	0.326
NPC1	O15118-1.2	C334L	Neutral	0.241
NPC1	O15118-1.2	C334M	Neutral	0.27
NPC1	O15118-1.2	C334N	Neutral	0.303
NPC1	O15118-1.2	C334P	Neutral	0.394
NPC1	O15118-1.2	C334Q	Neutral	0.355
NPC1	O15118-1.2	C334R	Neutral	0.342
NPC1	O15118-1.2	C334S	Neutral	0.198
NPC1	O15118-1.2	C334T	Neutral	0.208
NPC1	O15118-1.2	C334V	Neutral	0.249
NPC1	O15118-1.2	C334W	Neutral	0.329
NPC1	O15118-1.2	C334Y	Neutral	0.394
NPC1	O15118-1.2	L335A	Pathogenic	0.913
NPC1	O15118-1.2	L335C	Pathogenic	0.922
NPC1	O15118-1.2	L335D	Pathogenic	0.953
NPC1	O15118-1.2	L335E	Pathogenic	0.928
NPC1	O15118-1.2	L335F	Pathogenic	0.893
NPC1	O15118-1.2	L335G	Pathogenic	0.971
NPC1	O15118-1.2	L335H	Pathogenic	0.941
NPC1	O15118-1.2	L335I	Pathogenic	0.783
NPC1	O15118-1.2	L335K	Pathogenic	0.884
NPC1	O15118-1.2	L335M	Pathogenic	0.762
NPC1	O15118-1.2	L335N	Pathogenic	0.934
NPC1	O15118-1.2	L335P	Pathogenic	0.958
NPC1	O15118-1.2	L335Q	Pathogenic	0.907
NPC1	O15118-1.2	L335R	Pathogenic	0.892
NPC1	O15118-1.2	L335S	Pathogenic	0.93
NPC1	O15118-1.2	L335T	Pathogenic	0.899
NPC1	O15118-1.2	L335V	Pathogenic	0.84
NPC1	O15118-1.2	L335W	Pathogenic	0.949
NPC1	O15118-1.2	L335Y	Pathogenic	0.911
NPC1	O15118-1.2	R336A	Neutral	0.49
NPC1	O15118-1.2	R336C	Pathogenic	0.597
NPC1	O15118-1.2	R336D	Pathogenic	0.636
NPC1	O15118-1.2	R336E	Neutral	0.41
NPC1	O15118-1.2	R336F	Neutral	0.457
NPC1	O15118-1.2	R336G	Pathogenic	0.637
NPC1	O15118-1.2	R336H	Neutral	0.337
NPC1	O15118-1.2	R336I	Neutral	0.473
NPC1	O15118-1.2	R336K	Neutral	0.236
NPC1	O15118-1.2	R336L	Neutral	0.387
NPC1	O15118-1.2	R336M	Neutral	0.334
NPC1	O15118-1.2	R336N	Neutral	0.426
NPC1	O15118-1.2	R336P	Pathogenic	0.518
NPC1	O15118-1.2	R336Q	Neutral	0.285
NPC1	O15118-1.2	R336S	Pathogenic	0.51
NPC1	O15118-1.2	R336T	Neutral	0.455
NPC1	O15118-1.2	R336V	Pathogenic	0.55
NPC1	O15118-1.2	R336W	Neutral	0.422
NPC1	O15118-1.2	R336Y	Neutral	0.421
NPC1	O15118-1.2	R337A	Neutral	0.224
NPC1	O15118-1.2	R337C	Neutral	0.308
NPC1	O15118-1.2	R337D	Neutral	0.344
NPC1	O15118-1.2	R337E	Neutral	0.172
NPC1	O15118-1.2	R337F	Neutral	0.202
NPC1	O15118-1.2	R337G	Neutral	0.345
NPC1	O15118-1.2	R337H	Neutral	0.132
NPC1	O15118-1.2	R337I	Neutral	0.212
NPC1	O15118-1.2	R337K	Neutral	0.085
NPC1	O15118-1.2	R337L	Neutral	0.159
NPC1	O15118-1.2	R337M	Neutral	0.131
NPC1	O15118-1.2	R337N	Neutral	0.182
NPC1	O15118-1.2	R337P	Neutral	0.243
NPC1	O15118-1.2	R337Q	Neutral	0.107
NPC1	O15118-1.2	R337S	Neutral	0.238
NPC1	O15118-1.2	R337T	Neutral	0.2
NPC1	O15118-1.2	R337V	Neutral	0.268
NPC1	O15118-1.2	R337W	Neutral	0.18
NPC1	O15118-1.2	R337Y	Neutral	0.179
NPC1	O15118-1.2	L338A	Neutral	0.251
NPC1	O15118-1.2	L338C	Neutral	0.272
NPC1	O15118-1.2	L338D	Neutral	0.392
NPC1	O15118-1.2	L338E	Neutral	0.291
NPC1	O15118-1.2	L338F	Neutral	0.21
NPC1	O15118-1.2	L338G	Pathogenic	0.519
NPC1	O15118-1.2	L338H	Neutral	0.334
NPC1	O15118-1.2	L338I	Neutral	0.103
NPC1	O15118-1.2	L338K	Neutral	0.195
NPC1	O15118-1.2	L338M	Neutral	0.092
NPC1	O15118-1.2	L338N	Neutral	0.31
NPC1	O15118-1.2	L338P	Neutral	0.419
NPC1	O15118-1.2	L338Q	Neutral	0.237
NPC1	O15118-1.2	L338R	Neutral	0.207
NPC1	O15118-1.2	L338S	Neutral	0.297
NPC1	O15118-1.2	L338T	Neutral	0.219
NPC1	O15118-1.2	L338V	Neutral	0.143
NPC1	O15118-1.2	L338W	Neutral	0.369
NPC1	O15118-1.2	L338Y	Neutral	0.246
NPC1	O15118-1.2	F339A	Pathogenic	0.966
NPC1	O15118-1.2	F339C	Pathogenic	0.969
NPC1	O15118-1.2	F339D	Pathogenic	0.962
NPC1	O15118-1.2	F339E	Pathogenic	0.96
NPC1	O15118-1.2	F339G	Pathogenic	0.977
NPC1	O15118-1.2	F339H	Pathogenic	0.931
NPC1	O15118-1.2	F339I	Pathogenic	0.938
NPC1	O15118-1.2	F339K	Pathogenic	0.947
NPC1	O15118-1.2	F339L	Pathogenic	0.937
NPC1	O15118-1.2	F339M	Pathogenic	0.927
NPC1	O15118-1.2	F339N	Pathogenic	0.963
NPC1	O15118-1.2	F339P	Pathogenic	0.984
NPC1	O15118-1.2	F339Q	Pathogenic	0.964
NPC1	O15118-1.2	F339R	Pathogenic	0.951
NPC1	O15118-1.2	F339S	Pathogenic	0.961
NPC1	O15118-1.2	F339T	Pathogenic	0.96
NPC1	O15118-1.2	F339V	Pathogenic	0.954
NPC1	O15118-1.2	F339W	Pathogenic	0.908
NPC1	O15118-1.2	F339Y	Pathogenic	0.779
NPC1	O15118-1.2	T340A	Neutral	0.381
NPC1	O15118-1.2	T340C	Neutral	0.393
NPC1	O15118-1.2	T340D	Neutral	0.362
NPC1	O15118-1.2	T340E	Neutral	0.392
NPC1	O15118-1.2	T340F	Neutral	0.473
NPC1	O15118-1.2	T340G	Pathogenic	0.583
NPC1	O15118-1.2	T340H	Pathogenic	0.564
NPC1	O15118-1.2	T340I	Neutral	0.363
NPC1	O15118-1.2	T340K	Neutral	0.402
NPC1	O15118-1.2	T340L	Neutral	0.37
NPC1	O15118-1.2	T340M	Neutral	0.408
NPC1	O15118-1.2	T340N	Neutral	0.291
NPC1	O15118-1.2	T340P	Neutral	0.408
NPC1	O15118-1.2	T340Q	Neutral	0.433
NPC1	O15118-1.2	T340R	Neutral	0.42
NPC1	O15118-1.2	T340S	Neutral	0.272
NPC1	O15118-1.2	T340V	Neutral	0.295
NPC1	O15118-1.2	T340W	Neutral	0.477
NPC1	O15118-1.2	T340Y	Pathogenic	0.551
NPC1	O15118-1.2	R341A	Neutral	0.311
NPC1	O15118-1.2	R341C	Neutral	0.41
NPC1	O15118-1.2	R341D	Neutral	0.45
NPC1	O15118-1.2	R341E	Neutral	0.245
NPC1	O15118-1.2	R341F	Neutral	0.283
NPC1	O15118-1.2	R341G	Neutral	0.452
NPC1	O15118-1.2	R341H	Neutral	0.193
NPC1	O15118-1.2	R341I	Neutral	0.296
NPC1	O15118-1.2	R341K	Neutral	0.126
NPC1	O15118-1.2	R341L	Neutral	0.228
NPC1	O15118-1.2	R341M	Neutral	0.19
NPC1	O15118-1.2	R341N	Neutral	0.258
NPC1	O15118-1.2	R341P	Neutral	0.335
NPC1	O15118-1.2	R341Q	Neutral	0.157
NPC1	O15118-1.2	R341S	Neutral	0.328
NPC1	O15118-1.2	R341T	Neutral	0.281
NPC1	O15118-1.2	R341V	Neutral	0.364
NPC1	O15118-1.2	R341W	Neutral	0.255
NPC1	O15118-1.2	R341Y	Neutral	0.254
NPC1	O15118-1.2	W342A	Pathogenic	0.985
NPC1	O15118-1.2	W342C	Pathogenic	0.98
NPC1	O15118-1.2	W342D	Pathogenic	0.983
NPC1	O15118-1.2	W342E	Pathogenic	0.973
NPC1	O15118-1.2	W342F	Pathogenic	0.937
NPC1	O15118-1.2	W342G	Pathogenic	0.978
NPC1	O15118-1.2	W342H	Pathogenic	0.968
NPC1	O15118-1.2	W342I	Pathogenic	0.987
NPC1	O15118-1.2	W342K	Pathogenic	0.965
NPC1	O15118-1.2	W342L	Pathogenic	0.98
NPC1	O15118-1.2	W342M	Pathogenic	0.966
NPC1	O15118-1.2	W342N	Pathogenic	0.983
NPC1	O15118-1.2	W342P	Pathogenic	0.99
NPC1	O15118-1.2	W342Q	Pathogenic	0.965
NPC1	O15118-1.2	W342R	Pathogenic	0.962
NPC1	O15118-1.2	W342S	Pathogenic	0.982
NPC1	O15118-1.2	W342T	Pathogenic	0.974
NPC1	O15118-1.2	W342V	Pathogenic	0.986
NPC1	O15118-1.2	W342Y	Pathogenic	0.881
NPC1	O15118-1.2	G343A	Pathogenic	0.95
NPC1	O15118-1.2	G343C	Pathogenic	0.982
NPC1	O15118-1.2	G343D	Pathogenic	0.965
NPC1	O15118-1.2	G343E	Pathogenic	0.979
NPC1	O15118-1.2	G343F	Pathogenic	0.982
NPC1	O15118-1.2	G343H	Pathogenic	0.983
NPC1	O15118-1.2	G343I	Pathogenic	0.987
NPC1	O15118-1.2	G343K	Pathogenic	0.98
NPC1	O15118-1.2	G343L	Pathogenic	0.987
NPC1	O15118-1.2	G343M	Pathogenic	0.984
NPC1	O15118-1.2	G343N	Pathogenic	0.953
NPC1	O15118-1.2	G343P	Pathogenic	0.976
NPC1	O15118-1.2	G343Q	Pathogenic	0.982
NPC1	O15118-1.2	G343R	Pathogenic	0.981
NPC1	O15118-1.2	G343S	Pathogenic	0.955
NPC1	O15118-1.2	G343T	Pathogenic	0.98
NPC1	O15118-1.2	G343V	Pathogenic	0.982
NPC1	O15118-1.2	G343W	Pathogenic	0.975
NPC1	O15118-1.2	G343Y	Pathogenic	0.987
NPC1	O15118-1.2	S344A	Neutral	0.176
NPC1	O15118-1.2	S344C	Neutral	0.277
NPC1	O15118-1.2	S344D	Neutral	0.228
NPC1	O15118-1.2	S344E	Neutral	0.256
NPC1	O15118-1.2	S344F	Neutral	0.368
NPC1	O15118-1.2	S344G	Neutral	0.28
NPC1	O15118-1.2	S344H	Neutral	0.382
NPC1	O15118-1.2	S344I	Neutral	0.351
NPC1	O15118-1.2	S344K	Neutral	0.264
NPC1	O15118-1.2	S344L	Neutral	0.359
NPC1	O15118-1.2	S344M	Neutral	0.308
NPC1	O15118-1.2	S344N	Neutral	0.18
NPC1	O15118-1.2	S344P	Neutral	0.3
NPC1	O15118-1.2	S344Q	Neutral	0.29
NPC1	O15118-1.2	S344R	Neutral	0.362
NPC1	O15118-1.2	S344T	Neutral	0.191
NPC1	O15118-1.2	S344V	Neutral	0.37
NPC1	O15118-1.2	S344W	Neutral	0.465
NPC1	O15118-1.2	S344Y	Neutral	0.442
NPC1	O15118-1.2	F345A	Pathogenic	0.636
NPC1	O15118-1.2	F345C	Pathogenic	0.661
NPC1	O15118-1.2	F345D	Pathogenic	0.608
NPC1	O15118-1.2	F345E	Pathogenic	0.592
NPC1	O15118-1.2	F345G	Pathogenic	0.722
NPC1	O15118-1.2	F345H	Neutral	0.451
NPC1	O15118-1.2	F345I	Neutral	0.482
NPC1	O15118-1.2	F345K	Pathogenic	0.525
NPC1	O15118-1.2	F345L	Neutral	0.476
NPC1	O15118-1.2	F345M	Neutral	0.437
NPC1	O15118-1.2	F345N	Pathogenic	0.614
NPC1	O15118-1.2	F345P	Pathogenic	0.79
NPC1	O15118-1.2	F345Q	Pathogenic	0.618
NPC1	O15118-1.2	F345R	Pathogenic	0.543
NPC1	O15118-1.2	F345S	Pathogenic	0.6
NPC1	O15118-1.2	F345T	Pathogenic	0.594
NPC1	O15118-1.2	F345V	Pathogenic	0.56
NPC1	O15118-1.2	F345W	Neutral	0.377
NPC1	O15118-1.2	F345Y	Neutral	0.178
NPC1	O15118-1.2	C346A	Pathogenic	0.864
NPC1	O15118-1.2	C346D	Pathogenic	0.929
NPC1	O15118-1.2	C346E	Pathogenic	0.957
NPC1	O15118-1.2	C346F	Pathogenic	0.941
NPC1	O15118-1.2	C346G	Pathogenic	0.954
NPC1	O15118-1.2	C346H	Pathogenic	0.954
NPC1	O15118-1.2	C346I	Pathogenic	0.909
NPC1	O15118-1.2	C346K	Pathogenic	0.94
NPC1	O15118-1.2	C346L	Pathogenic	0.912
NPC1	O15118-1.2	C346M	Pathogenic	0.924
NPC1	O15118-1.2	C346N	Pathogenic	0.934
NPC1	O15118-1.2	C346P	Pathogenic	0.955
NPC1	O15118-1.2	C346Q	Pathogenic	0.947
NPC1	O15118-1.2	C346R	Pathogenic	0.944
NPC1	O15118-1.2	C346S	Pathogenic	0.89
NPC1	O15118-1.2	C346T	Pathogenic	0.896
NPC1	O15118-1.2	C346V	Pathogenic	0.916
NPC1	O15118-1.2	C346W	Pathogenic	0.941
NPC1	O15118-1.2	C346Y	Pathogenic	0.955
NPC1	O15118-1.2	V347A	Pathogenic	0.648
NPC1	O15118-1.2	V347C	Pathogenic	0.751
NPC1	O15118-1.2	V347D	Pathogenic	0.779
NPC1	O15118-1.2	V347E	Pathogenic	0.703
NPC1	O15118-1.2	V347F	Pathogenic	0.742
NPC1	O15118-1.2	V347G	Pathogenic	0.855
NPC1	O15118-1.2	V347H	Pathogenic	0.826
NPC1	O15118-1.2	V347I	Neutral	0.364
NPC1	O15118-1.2	V347K	Pathogenic	0.711
NPC1	O15118-1.2	V347L	Pathogenic	0.562
NPC1	O15118-1.2	V347M	Pathogenic	0.6
NPC1	O15118-1.2	V347N	Pathogenic	0.784
NPC1	O15118-1.2	V347P	Pathogenic	0.799
NPC1	O15118-1.2	V347Q	Pathogenic	0.737
NPC1	O15118-1.2	V347R	Pathogenic	0.796
NPC1	O15118-1.2	V347S	Pathogenic	0.774
NPC1	O15118-1.2	V347T	Pathogenic	0.607
NPC1	O15118-1.2	V347W	Pathogenic	0.864
NPC1	O15118-1.2	V347Y	Pathogenic	0.768
NPC1	O15118-1.2	R348A	Pathogenic	0.664
NPC1	O15118-1.2	R348C	Pathogenic	0.753
NPC1	O15118-1.2	R348D	Pathogenic	0.783
NPC1	O15118-1.2	R348E	Pathogenic	0.588
NPC1	O15118-1.2	R348F	Pathogenic	0.634
NPC1	O15118-1.2	R348G	Pathogenic	0.783
NPC1	O15118-1.2	R348H	Pathogenic	0.512
NPC1	O15118-1.2	R348I	Pathogenic	0.649
NPC1	O15118-1.2	R348K	Neutral	0.388
NPC1	O15118-1.2	R348L	Pathogenic	0.565
NPC1	O15118-1.2	R348M	Pathogenic	0.508
NPC1	O15118-1.2	R348N	Pathogenic	0.604
NPC1	O15118-1.2	R348P	Pathogenic	0.689
NPC1	O15118-1.2	R348Q	Neutral	0.451
NPC1	O15118-1.2	R348S	Pathogenic	0.682
NPC1	O15118-1.2	R348T	Pathogenic	0.632
NPC1	O15118-1.2	R348V	Pathogenic	0.716
NPC1	O15118-1.2	R348W	Pathogenic	0.601
NPC1	O15118-1.2	R348Y	Pathogenic	0.6
NPC1	O15118-1.2	N349A	Pathogenic	0.64
NPC1	O15118-1.2	N349C	Pathogenic	0.65
NPC1	O15118-1.2	N349D	Neutral	0.381
NPC1	O15118-1.2	N349E	Neutral	0.499
NPC1	O15118-1.2	N349F	Pathogenic	0.629
NPC1	O15118-1.2	N349G	Pathogenic	0.505
NPC1	O15118-1.2	N349H	Neutral	0.362
NPC1	O15118-1.2	N349I	Pathogenic	0.612
NPC1	O15118-1.2	N349K	Pathogenic	0.509
NPC1	O15118-1.2	N349L	Pathogenic	0.62
NPC1	O15118-1.2	N349M	Pathogenic	0.565
NPC1	O15118-1.2	N349P	Pathogenic	0.574
NPC1	O15118-1.2	N349Q	Neutral	0.478
NPC1	O15118-1.2	N349R	Pathogenic	0.527
NPC1	O15118-1.2	N349S	Neutral	0.376
NPC1	O15118-1.2	N349T	Neutral	0.416
NPC1	O15118-1.2	N349V	Pathogenic	0.631
NPC1	O15118-1.2	N349W	Pathogenic	0.717
NPC1	O15118-1.2	N349Y	Pathogenic	0.611
NPC1	O15118-1.2	P350A	Pathogenic	0.962
NPC1	O15118-1.2	P350C	Pathogenic	0.981
NPC1	O15118-1.2	P350D	Pathogenic	0.939
NPC1	O15118-1.2	P350E	Pathogenic	0.947
NPC1	O15118-1.2	P350F	Pathogenic	0.987
NPC1	O15118-1.2	P350G	Pathogenic	0.974
NPC1	O15118-1.2	P350H	Pathogenic	0.973
NPC1	O15118-1.2	P350I	Pathogenic	0.979
NPC1	O15118-1.2	P350K	Pathogenic	0.949
NPC1	O15118-1.2	P350L	Pathogenic	0.98
NPC1	O15118-1.2	P350M	Pathogenic	0.975
NPC1	O15118-1.2	P350N	Pathogenic	0.961
NPC1	O15118-1.2	P350Q	Pathogenic	0.955
NPC1	O15118-1.2	P350R	Pathogenic	0.967
NPC1	O15118-1.2	P350S	Pathogenic	0.956
NPC1	O15118-1.2	P350T	Pathogenic	0.957
NPC1	O15118-1.2	P350V	Pathogenic	0.972
NPC1	O15118-1.2	P350W	Pathogenic	0.987
NPC1	O15118-1.2	P350Y	Pathogenic	0.986
NPC1	O15118-1.2	G351A	Neutral	0.05
NPC1	O15118-1.2	G351C	Neutral	0.13
NPC1	O15118-1.2	G351D	Neutral	0.071
NPC1	O15118-1.2	G351E	Neutral	0.116
NPC1	O15118-1.2	G351F	Neutral	0.133
NPC1	O15118-1.2	G351H	Neutral	0.14
NPC1	O15118-1.2	G351I	Neutral	0.174
NPC1	O15118-1.2	G351K	Neutral	0.12
NPC1	O15118-1.2	G351L	Neutral	0.179
NPC1	O15118-1.2	G351M	Neutral	0.147
NPC1	O15118-1.2	G351N	Neutral	0.054
NPC1	O15118-1.2	G351P	Neutral	0.102
NPC1	O15118-1.2	G351Q	Neutral	0.134
NPC1	O15118-1.2	G351R	Neutral	0.128
NPC1	O15118-1.2	G351S	Neutral	0.056
NPC1	O15118-1.2	G351T	Neutral	0.119
NPC1	O15118-1.2	G351V	Neutral	0.134
NPC1	O15118-1.2	G351W	Neutral	0.096
NPC1	O15118-1.2	G351Y	Neutral	0.173
NPC1	O15118-1.2	C352A	Neutral	0.038
NPC1	O15118-1.2	C352D	Neutral	0.075
NPC1	O15118-1.2	C352E	Neutral	0.122
NPC1	O15118-1.2	C352F	Neutral	0.09
NPC1	O15118-1.2	C352G	Neutral	0.114
NPC1	O15118-1.2	C352H	Neutral	0.114
NPC1	O15118-1.2	C352I	Neutral	0.059
NPC1	O15118-1.2	C352K	Neutral	0.09
NPC1	O15118-1.2	C352L	Neutral	0.061
NPC1	O15118-1.2	C352M	Neutral	0.07
NPC1	O15118-1.2	C352N	Neutral	0.081
NPC1	O15118-1.2	C352P	Neutral	0.117
NPC1	O15118-1.2	C352Q	Neutral	0.101
NPC1	O15118-1.2	C352R	Neutral	0.096
NPC1	O15118-1.2	C352S	Neutral	0.048
NPC1	O15118-1.2	C352T	Neutral	0.051
NPC1	O15118-1.2	C352V	Neutral	0.063
NPC1	O15118-1.2	C352W	Neutral	0.091
NPC1	O15118-1.2	C352Y	Neutral	0.117
NPC1	O15118-1.2	V353A	Neutral	0.461
NPC1	O15118-1.2	V353C	Pathogenic	0.584
NPC1	O15118-1.2	V353D	Pathogenic	0.622
NPC1	O15118-1.2	V353E	Pathogenic	0.523
NPC1	O15118-1.2	V353F	Pathogenic	0.572
NPC1	O15118-1.2	V353G	Pathogenic	0.733
NPC1	O15118-1.2	V353H	Pathogenic	0.688
NPC1	O15118-1.2	V353I	Neutral	0.21
NPC1	O15118-1.2	V353K	Pathogenic	0.533
NPC1	O15118-1.2	V353L	Neutral	0.374
NPC1	O15118-1.2	V353M	Neutral	0.411
NPC1	O15118-1.2	V353N	Pathogenic	0.628
NPC1	O15118-1.2	V353P	Pathogenic	0.648
NPC1	O15118-1.2	V353Q	Pathogenic	0.565
NPC1	O15118-1.2	V353R	Pathogenic	0.644
NPC1	O15118-1.2	V353S	Pathogenic	0.614
NPC1	O15118-1.2	V353T	Neutral	0.418
NPC1	O15118-1.2	V353W	Pathogenic	0.746
NPC1	O15118-1.2	V353Y	Pathogenic	0.607
NPC1	O15118-1.2	I354A	Neutral	0.383
NPC1	O15118-1.2	I354C	Neutral	0.409
NPC1	O15118-1.2	I354D	Neutral	0.448
NPC1	O15118-1.2	I354E	Neutral	0.432
NPC1	O15118-1.2	I354F	Neutral	0.343
NPC1	O15118-1.2	I354G	Pathogenic	0.667
NPC1	O15118-1.2	I354H	Neutral	0.482
NPC1	O15118-1.2	I354K	Neutral	0.398
NPC1	O15118-1.2	I354L	Neutral	0.18
NPC1	O15118-1.2	I354M	Neutral	0.216
NPC1	O15118-1.2	I354N	Neutral	0.454
NPC1	O15118-1.2	I354P	Pathogenic	0.572
NPC1	O15118-1.2	I354Q	Neutral	0.459
NPC1	O15118-1.2	I354R	Neutral	0.415
NPC1	O15118-1.2	I354S	Neutral	0.44
NPC1	O15118-1.2	I354T	Neutral	0.343
NPC1	O15118-1.2	I354V	Neutral	0.125
NPC1	O15118-1.2	I354W	Pathogenic	0.63
NPC1	O15118-1.2	I354Y	Neutral	0.377
NPC1	O15118-1.2	F355A	Neutral	0.335
NPC1	O15118-1.2	F355C	Neutral	0.36
NPC1	O15118-1.2	F355D	Neutral	0.31
NPC1	O15118-1.2	F355E	Neutral	0.296
NPC1	O15118-1.2	F355G	Neutral	0.429
NPC1	O15118-1.2	F355H	Neutral	0.192
NPC1	O15118-1.2	F355I	Neutral	0.212
NPC1	O15118-1.2	F355K	Neutral	0.242
NPC1	O15118-1.2	F355L	Neutral	0.208
NPC1	O15118-1.2	F355M	Neutral	0.183
NPC1	O15118-1.2	F355N	Neutral	0.315
NPC1	O15118-1.2	F355P	Pathogenic	0.521
NPC1	O15118-1.2	F355Q	Neutral	0.319
NPC1	O15118-1.2	F355R	Neutral	0.256
NPC1	O15118-1.2	F355S	Neutral	0.303
NPC1	O15118-1.2	F355T	Neutral	0.298
NPC1	O15118-1.2	F355V	Neutral	0.269
NPC1	O15118-1.2	F355W	Neutral	0.149
NPC1	O15118-1.2	F355Y	Neutral	0.059
NPC1	O15118-1.2	F356A	Neutral	0.18
NPC1	O15118-1.2	F356C	Neutral	0.196
NPC1	O15118-1.2	F356D	Neutral	0.163
NPC1	O15118-1.2	F356E	Neutral	0.154
NPC1	O15118-1.2	F356G	Neutral	0.246
NPC1	O15118-1.2	F356H	Neutral	0.094
NPC1	O15118-1.2	F356I	Neutral	0.105
NPC1	O15118-1.2	F356K	Neutral	0.122
NPC1	O15118-1.2	F356L	Neutral	0.102
NPC1	O15118-1.2	F356M	Neutral	0.089
NPC1	O15118-1.2	F356N	Neutral	0.167
NPC1	O15118-1.2	F356P	Neutral	0.321
NPC1	O15118-1.2	F356Q	Neutral	0.169
NPC1	O15118-1.2	F356R	Neutral	0.13
NPC1	O15118-1.2	F356S	Neutral	0.159
NPC1	O15118-1.2	F356T	Neutral	0.156
NPC1	O15118-1.2	F356V	Neutral	0.138
NPC1	O15118-1.2	F356W	Neutral	0.071
NPC1	O15118-1.2	F356Y	Neutral	0.026
NPC1	O15118-1.2	S357A	Neutral	0.218
NPC1	O15118-1.2	S357C	Neutral	0.335
NPC1	O15118-1.2	S357D	Neutral	0.279
NPC1	O15118-1.2	S357E	Neutral	0.311
NPC1	O15118-1.2	S357F	Neutral	0.432
NPC1	O15118-1.2	S357G	Neutral	0.338
NPC1	O15118-1.2	S357H	Neutral	0.448
NPC1	O15118-1.2	S357I	Neutral	0.415
NPC1	O15118-1.2	S357K	Neutral	0.32
NPC1	O15118-1.2	S357L	Neutral	0.423
NPC1	O15118-1.2	S357M	Neutral	0.368
NPC1	O15118-1.2	S357N	Neutral	0.223
NPC1	O15118-1.2	S357P	Neutral	0.36
NPC1	O15118-1.2	S357Q	Neutral	0.349
NPC1	O15118-1.2	S357R	Neutral	0.427
NPC1	O15118-1.2	S357T	Neutral	0.236
NPC1	O15118-1.2	S357V	Neutral	0.434
NPC1	O15118-1.2	S357W	Pathogenic	0.532
NPC1	O15118-1.2	S357Y	Pathogenic	0.51
NPC1	O15118-1.2	L358A	Neutral	0.161
NPC1	O15118-1.2	L358C	Neutral	0.177
NPC1	O15118-1.2	L358D	Neutral	0.27
NPC1	O15118-1.2	L358E	Neutral	0.191
NPC1	O15118-1.2	L358F	Neutral	0.133
NPC1	O15118-1.2	L358G	Neutral	0.383
NPC1	O15118-1.2	L358H	Neutral	0.224
NPC1	O15118-1.2	L358I	Neutral	0.062
NPC1	O15118-1.2	L358K	Neutral	0.122
NPC1	O15118-1.2	L358M	Neutral	0.055
NPC1	O15118-1.2	L358N	Neutral	0.205
NPC1	O15118-1.2	L358P	Neutral	0.293
NPC1	O15118-1.2	L358Q	Neutral	0.152
NPC1	O15118-1.2	L358R	Neutral	0.13
NPC1	O15118-1.2	L358S	Neutral	0.196
NPC1	O15118-1.2	L358T	Neutral	0.139
NPC1	O15118-1.2	L358V	Neutral	0.087
NPC1	O15118-1.2	L358W	Neutral	0.252
NPC1	O15118-1.2	L358Y	Neutral	0.158
NPC1	O15118-1.2	V359A	Neutral	0.115
NPC1	O15118-1.2	V359C	Neutral	0.175
NPC1	O15118-1.2	V359D	Neutral	0.199
NPC1	O15118-1.2	V359E	Neutral	0.143
NPC1	O15118-1.2	V359F	Neutral	0.169
NPC1	O15118-1.2	V359G	Neutral	0.294
NPC1	O15118-1.2	V359H	Neutral	0.25
NPC1	O15118-1.2	V359I	Neutral	0.039
NPC1	O15118-1.2	V359K	Neutral	0.148
NPC1	O15118-1.2	V359L	Neutral	0.083
NPC1	O15118-1.2	V359M	Neutral	0.096
NPC1	O15118-1.2	V359N	Neutral	0.204
NPC1	O15118-1.2	V359P	Neutral	0.218
NPC1	O15118-1.2	V359Q	Neutral	0.165
NPC1	O15118-1.2	V359R	Neutral	0.215
NPC1	O15118-1.2	V359S	Neutral	0.194
NPC1	O15118-1.2	V359T	Neutral	0.098
NPC1	O15118-1.2	V359W	Neutral	0.308
NPC1	O15118-1.2	V359Y	Neutral	0.189
NPC1	O15118-1.2	F360A	Neutral	0.379
NPC1	O15118-1.2	F360C	Neutral	0.405
NPC1	O15118-1.2	F360D	Neutral	0.352
NPC1	O15118-1.2	F360E	Neutral	0.337
NPC1	O15118-1.2	F360G	Neutral	0.476
NPC1	O15118-1.2	F360H	Neutral	0.223
NPC1	O15118-1.2	F360I	Neutral	0.246
NPC1	O15118-1.2	F360K	Neutral	0.279
NPC1	O15118-1.2	F360L	Neutral	0.241
NPC1	O15118-1.2	F360M	Neutral	0.214
NPC1	O15118-1.2	F360N	Neutral	0.358
NPC1	O15118-1.2	F360P	Pathogenic	0.569
NPC1	O15118-1.2	F360Q	Neutral	0.362
NPC1	O15118-1.2	F360R	Neutral	0.294
NPC1	O15118-1.2	F360S	Neutral	0.344
NPC1	O15118-1.2	F360T	Neutral	0.339
NPC1	O15118-1.2	F360V	Neutral	0.309
NPC1	O15118-1.2	F360W	Neutral	0.175
NPC1	O15118-1.2	F360Y	Neutral	0.07
NPC1	O15118-1.2	I361A	Neutral	0.363
NPC1	O15118-1.2	I361C	Neutral	0.388
NPC1	O15118-1.2	I361D	Neutral	0.427
NPC1	O15118-1.2	I361E	Neutral	0.411
NPC1	O15118-1.2	I361F	Neutral	0.324
NPC1	O15118-1.2	I361G	Pathogenic	0.647
NPC1	O15118-1.2	I361H	Neutral	0.46
NPC1	O15118-1.2	I361K	Neutral	0.377
NPC1	O15118-1.2	I361L	Neutral	0.168
NPC1	O15118-1.2	I361M	Neutral	0.202
NPC1	O15118-1.2	I361N	Neutral	0.433
NPC1	O15118-1.2	I361P	Pathogenic	0.551
NPC1	O15118-1.2	I361Q	Neutral	0.437
NPC1	O15118-1.2	I361R	Neutral	0.395
NPC1	O15118-1.2	I361S	Neutral	0.419
NPC1	O15118-1.2	I361T	Neutral	0.324
NPC1	O15118-1.2	I361V	Neutral	0.116
NPC1	O15118-1.2	I361W	Pathogenic	0.61
NPC1	O15118-1.2	I361Y	Neutral	0.357
NPC1	O15118-1.2	T362A	Neutral	0.093
NPC1	O15118-1.2	T362C	Neutral	0.097
NPC1	O15118-1.2	T362D	Neutral	0.086
NPC1	O15118-1.2	T362E	Neutral	0.097
NPC1	O15118-1.2	T362F	Neutral	0.13
NPC1	O15118-1.2	T362G	Neutral	0.189
NPC1	O15118-1.2	T362H	Neutral	0.177
NPC1	O15118-1.2	T362I	Neutral	0.087
NPC1	O15118-1.2	T362K	Neutral	0.101
NPC1	O15118-1.2	T362L	Neutral	0.089
NPC1	O15118-1.2	T362M	Neutral	0.103
NPC1	O15118-1.2	T362N	Neutral	0.064
NPC1	O15118-1.2	T362P	Neutral	0.103
NPC1	O15118-1.2	T362Q	Neutral	0.113
NPC1	O15118-1.2	T362R	Neutral	0.108
NPC1	O15118-1.2	T362S	Neutral	0.059
NPC1	O15118-1.2	T362V	Neutral	0.065
NPC1	O15118-1.2	T362W	Neutral	0.132
NPC1	O15118-1.2	T362Y	Neutral	0.17
NPC1	O15118-1.2	A363C	Neutral	0.088
NPC1	O15118-1.2	A363D	Neutral	0.158
NPC1	O15118-1.2	A363E	Neutral	0.13
NPC1	O15118-1.2	A363F	Neutral	0.177
NPC1	O15118-1.2	A363G	Neutral	0.098
NPC1	O15118-1.2	A363H	Neutral	0.23
NPC1	O15118-1.2	A363I	Neutral	0.12
NPC1	O15118-1.2	A363K	Neutral	0.134
NPC1	O15118-1.2	A363L	Neutral	0.123
NPC1	O15118-1.2	A363M	Neutral	0.141
NPC1	O15118-1.2	A363N	Neutral	0.17
NPC1	O15118-1.2	A363P	Neutral	0.137
NPC1	O15118-1.2	A363Q	Neutral	0.15
NPC1	O15118-1.2	A363R	Neutral	0.143
NPC1	O15118-1.2	A363S	Neutral	0.063
NPC1	O15118-1.2	A363T	Neutral	0.11
NPC1	O15118-1.2	A363V	Neutral	0.091
NPC1	O15118-1.2	A363W	Neutral	0.243
NPC1	O15118-1.2	A363Y	Neutral	0.227
NPC1	O15118-1.2	C364A	Neutral	0.281
NPC1	O15118-1.2	C364D	Neutral	0.444
NPC1	O15118-1.2	C364E	Pathogenic	0.578
NPC1	O15118-1.2	C364F	Neutral	0.493
NPC1	O15118-1.2	C364G	Pathogenic	0.558
NPC1	O15118-1.2	C364H	Pathogenic	0.56
NPC1	O15118-1.2	C364I	Neutral	0.381
NPC1	O15118-1.2	C364K	Neutral	0.493
NPC1	O15118-1.2	C364L	Neutral	0.389
NPC1	O15118-1.2	C364M	Neutral	0.427
NPC1	O15118-1.2	C364N	Neutral	0.466
NPC1	O15118-1.2	C364P	Pathogenic	0.566
NPC1	O15118-1.2	C364Q	Pathogenic	0.525
NPC1	O15118-1.2	C364R	Pathogenic	0.511
NPC1	O15118-1.2	C364S	Neutral	0.331
NPC1	O15118-1.2	C364T	Neutral	0.345
NPC1	O15118-1.2	C364V	Neutral	0.4
NPC1	O15118-1.2	C364W	Neutral	0.497
NPC1	O15118-1.2	C364Y	Pathogenic	0.567
NPC1	O15118-1.2	S365A	Neutral	0.122
NPC1	O15118-1.2	S365C	Neutral	0.201
NPC1	O15118-1.2	S365D	Neutral	0.162
NPC1	O15118-1.2	S365E	Neutral	0.184
NPC1	O15118-1.2	S365F	Neutral	0.276
NPC1	O15118-1.2	S365G	Neutral	0.203
NPC1	O15118-1.2	S365H	Neutral	0.288
NPC1	O15118-1.2	S365I	Neutral	0.262
NPC1	O15118-1.2	S365K	Neutral	0.19
NPC1	O15118-1.2	S365L	Neutral	0.268
NPC1	O15118-1.2	S365M	Neutral	0.226
NPC1	O15118-1.2	S365N	Neutral	0.126
NPC1	O15118-1.2	S365P	Neutral	0.219
NPC1	O15118-1.2	S365Q	Neutral	0.211
NPC1	O15118-1.2	S365R	Neutral	0.271
NPC1	O15118-1.2	S365T	Neutral	0.134
NPC1	O15118-1.2	S365V	Neutral	0.277
NPC1	O15118-1.2	S365W	Neutral	0.362
NPC1	O15118-1.2	S365Y	Neutral	0.342
NPC1	O15118-1.2	S366A	Neutral	0.053
NPC1	O15118-1.2	S366C	Neutral	0.092
NPC1	O15118-1.2	S366D	Neutral	0.073
NPC1	O15118-1.2	S366E	Neutral	0.084
NPC1	O15118-1.2	S366F	Neutral	0.133
NPC1	O15118-1.2	S366G	Neutral	0.093
NPC1	O15118-1.2	S366H	Neutral	0.141
NPC1	O15118-1.2	S366I	Neutral	0.125
NPC1	O15118-1.2	S366K	Neutral	0.087
NPC1	O15118-1.2	S366L	Neutral	0.129
NPC1	O15118-1.2	S366M	Neutral	0.105
NPC1	O15118-1.2	S366N	Neutral	0.055
NPC1	O15118-1.2	S366P	Neutral	0.102
NPC1	O15118-1.2	S366Q	Neutral	0.098
NPC1	O15118-1.2	S366R	Neutral	0.131
NPC1	O15118-1.2	S366T	Neutral	0.059
NPC1	O15118-1.2	S366V	Neutral	0.134
NPC1	O15118-1.2	S366W	Neutral	0.187
NPC1	O15118-1.2	S366Y	Neutral	0.174
NPC1	O15118-1.2	G367A	Pathogenic	0.821
NPC1	O15118-1.2	G367C	Pathogenic	0.929
NPC1	O15118-1.2	G367D	Pathogenic	0.87
NPC1	O15118-1.2	G367E	Pathogenic	0.92
NPC1	O15118-1.2	G367F	Pathogenic	0.931
NPC1	O15118-1.2	G367H	Pathogenic	0.935
NPC1	O15118-1.2	G367I	Pathogenic	0.949
NPC1	O15118-1.2	G367K	Pathogenic	0.923
NPC1	O15118-1.2	G367L	Pathogenic	0.95
NPC1	O15118-1.2	G367M	Pathogenic	0.938
NPC1	O15118-1.2	G367N	Pathogenic	0.833
NPC1	O15118-1.2	G367P	Pathogenic	0.909
NPC1	O15118-1.2	G367Q	Pathogenic	0.932
NPC1	O15118-1.2	G367R	Pathogenic	0.928
NPC1	O15118-1.2	G367S	Pathogenic	0.839
NPC1	O15118-1.2	G367T	Pathogenic	0.922
NPC1	O15118-1.2	G367V	Pathogenic	0.932
NPC1	O15118-1.2	G367W	Pathogenic	0.903
NPC1	O15118-1.2	G367Y	Pathogenic	0.949
NPC1	O15118-1.2	L368A	Neutral	0.262
NPC1	O15118-1.2	L368C	Neutral	0.284
NPC1	O15118-1.2	L368D	Neutral	0.406
NPC1	O15118-1.2	L368E	Neutral	0.303
NPC1	O15118-1.2	L368F	Neutral	0.22
NPC1	O15118-1.2	L368G	Pathogenic	0.534
NPC1	O15118-1.2	L368H	Neutral	0.347
NPC1	O15118-1.2	L368I	Neutral	0.108
NPC1	O15118-1.2	L368K	Neutral	0.204
NPC1	O15118-1.2	L368M	Neutral	0.097
NPC1	O15118-1.2	L368N	Neutral	0.323
NPC1	O15118-1.2	L368P	Neutral	0.434
NPC1	O15118-1.2	L368Q	Neutral	0.248
NPC1	O15118-1.2	L368R	Neutral	0.217
NPC1	O15118-1.2	L368S	Neutral	0.31
NPC1	O15118-1.2	L368T	Neutral	0.23
NPC1	O15118-1.2	L368V	Neutral	0.15
NPC1	O15118-1.2	L368W	Neutral	0.383
NPC1	O15118-1.2	L368Y	Neutral	0.257
NPC1	O15118-1.2	V369A	Neutral	0.084
NPC1	O15118-1.2	V369C	Neutral	0.13
NPC1	O15118-1.2	V369D	Neutral	0.149
NPC1	O15118-1.2	V369E	Neutral	0.105
NPC1	O15118-1.2	V369F	Neutral	0.125
NPC1	O15118-1.2	V369G	Neutral	0.227
NPC1	O15118-1.2	V369H	Neutral	0.191
NPC1	O15118-1.2	V369I	Neutral	0.028
NPC1	O15118-1.2	V369K	Neutral	0.109
NPC1	O15118-1.2	V369L	Neutral	0.06
NPC1	O15118-1.2	V369M	Neutral	0.069
NPC1	O15118-1.2	V369N	Neutral	0.153
NPC1	O15118-1.2	V369P	Neutral	0.164
NPC1	O15118-1.2	V369Q	Neutral	0.122
NPC1	O15118-1.2	V369R	Neutral	0.162
NPC1	O15118-1.2	V369S	Neutral	0.145
NPC1	O15118-1.2	V369T	Neutral	0.071
NPC1	O15118-1.2	V369W	Neutral	0.239
NPC1	O15118-1.2	V369Y	Neutral	0.141
NPC1	O15118-1.2	F370A	Neutral	0.377
NPC1	O15118-1.2	F370C	Neutral	0.403
NPC1	O15118-1.2	F370D	Neutral	0.35
NPC1	O15118-1.2	F370E	Neutral	0.335
NPC1	O15118-1.2	F370G	Neutral	0.474
NPC1	O15118-1.2	F370H	Neutral	0.222
NPC1	O15118-1.2	F370I	Neutral	0.244
NPC1	O15118-1.2	F370K	Neutral	0.277
NPC1	O15118-1.2	F370L	Neutral	0.239
NPC1	O15118-1.2	F370M	Neutral	0.212
NPC1	O15118-1.2	F370N	Neutral	0.355
NPC1	O15118-1.2	F370P	Pathogenic	0.566
NPC1	O15118-1.2	F370Q	Neutral	0.359
NPC1	O15118-1.2	F370R	Neutral	0.292
NPC1	O15118-1.2	F370S	Neutral	0.342
NPC1	O15118-1.2	F370T	Neutral	0.337
NPC1	O15118-1.2	F370V	Neutral	0.306
NPC1	O15118-1.2	F370W	Neutral	0.173
NPC1	O15118-1.2	F370Y	Neutral	0.07
NPC1	O15118-1.2	V371A	Neutral	0.101
NPC1	O15118-1.2	V371C	Neutral	0.156
NPC1	O15118-1.2	V371D	Neutral	0.178
NPC1	O15118-1.2	V371E	Neutral	0.127
NPC1	O15118-1.2	V371F	Neutral	0.15
NPC1	O15118-1.2	V371G	Neutral	0.267
NPC1	O15118-1.2	V371H	Neutral	0.226
NPC1	O15118-1.2	V371I	Neutral	0.034
NPC1	O15118-1.2	V371K	Neutral	0.131
NPC1	O15118-1.2	V371L	Neutral	0.073
NPC1	O15118-1.2	V371M	Neutral	0.084
NPC1	O15118-1.2	V371N	Neutral	0.182
NPC1	O15118-1.2	V371P	Neutral	0.196
NPC1	O15118-1.2	V371Q	Neutral	0.147
NPC1	O15118-1.2	V371R	Neutral	0.193
NPC1	O15118-1.2	V371S	Neutral	0.174
NPC1	O15118-1.2	V371T	Neutral	0.087
NPC1	O15118-1.2	V371W	Neutral	0.28
NPC1	O15118-1.2	V371Y	Neutral	0.169
NPC1	O15118-1.2	R372A	Neutral	0.404
NPC1	O15118-1.2	R372C	Pathogenic	0.511
NPC1	O15118-1.2	R372D	Pathogenic	0.553
NPC1	O15118-1.2	R372E	Neutral	0.329
NPC1	O15118-1.2	R372F	Neutral	0.373
NPC1	O15118-1.2	R372G	Pathogenic	0.554
NPC1	O15118-1.2	R372H	Neutral	0.264
NPC1	O15118-1.2	R372I	Neutral	0.388
NPC1	O15118-1.2	R372K	Neutral	0.179
NPC1	O15118-1.2	R372L	Neutral	0.308
NPC1	O15118-1.2	R372M	Neutral	0.261
NPC1	O15118-1.2	R372N	Neutral	0.344
NPC1	O15118-1.2	R372P	Neutral	0.431
NPC1	O15118-1.2	R372Q	Neutral	0.22
NPC1	O15118-1.2	R372S	Neutral	0.423
NPC1	O15118-1.2	R372T	Neutral	0.371
NPC1	O15118-1.2	R372V	Neutral	0.463
NPC1	O15118-1.2	R372W	Neutral	0.341
NPC1	O15118-1.2	R372Y	Neutral	0.339
NPC1	O15118-1.2	V373A	Pathogenic	0.516
NPC1	O15118-1.2	V373C	Pathogenic	0.636
NPC1	O15118-1.2	V373D	Pathogenic	0.672
NPC1	O15118-1.2	V373E	Pathogenic	0.578
NPC1	O15118-1.2	V373F	Pathogenic	0.626
NPC1	O15118-1.2	V373G	Pathogenic	0.775
NPC1	O15118-1.2	V373H	Pathogenic	0.734
NPC1	O15118-1.2	V373I	Neutral	0.25
NPC1	O15118-1.2	V373K	Pathogenic	0.588
NPC1	O15118-1.2	V373L	Neutral	0.427
NPC1	O15118-1.2	V373M	Neutral	0.465
NPC1	O15118-1.2	V373N	Pathogenic	0.678
NPC1	O15118-1.2	V373P	Pathogenic	0.697
NPC1	O15118-1.2	V373Q	Pathogenic	0.619
NPC1	O15118-1.2	V373R	Pathogenic	0.693
NPC1	O15118-1.2	V373S	Pathogenic	0.665
NPC1	O15118-1.2	V373T	Neutral	0.473
NPC1	O15118-1.2	V373W	Pathogenic	0.786
NPC1	O15118-1.2	V373Y	Pathogenic	0.658
NPC1	O15118-1.2	T374A	Pathogenic	0.914
NPC1	O15118-1.2	T374C	Pathogenic	0.918
NPC1	O15118-1.2	T374D	Pathogenic	0.907
NPC1	O15118-1.2	T374E	Pathogenic	0.918
NPC1	O15118-1.2	T374F	Pathogenic	0.939
NPC1	O15118-1.2	T374G	Pathogenic	0.96
NPC1	O15118-1.2	T374H	Pathogenic	0.957
NPC1	O15118-1.2	T374I	Pathogenic	0.908
NPC1	O15118-1.2	T374K	Pathogenic	0.921
NPC1	O15118-1.2	T374L	Pathogenic	0.91
NPC1	O15118-1.2	T374M	Pathogenic	0.922
NPC1	O15118-1.2	T374N	Pathogenic	0.876
NPC1	O15118-1.2	T374P	Pathogenic	0.922
NPC1	O15118-1.2	T374Q	Pathogenic	0.93
NPC1	O15118-1.2	T374R	Pathogenic	0.926
NPC1	O15118-1.2	T374S	Pathogenic	0.866
NPC1	O15118-1.2	T374V	Pathogenic	0.878
NPC1	O15118-1.2	T374W	Pathogenic	0.94
NPC1	O15118-1.2	T374Y	Pathogenic	0.955
NPC1	O15118-1.2	T375A	Pathogenic	0.923
NPC1	O15118-1.2	T375C	Pathogenic	0.926
NPC1	O15118-1.2	T375D	Pathogenic	0.917
NPC1	O15118-1.2	T375E	Pathogenic	0.926
NPC1	O15118-1.2	T375F	Pathogenic	0.946
NPC1	O15118-1.2	T375G	Pathogenic	0.964
NPC1	O15118-1.2	T375H	Pathogenic	0.962
NPC1	O15118-1.2	T375I	Pathogenic	0.917
NPC1	O15118-1.2	T375K	Pathogenic	0.929
NPC1	O15118-1.2	T375L	Pathogenic	0.919
NPC1	O15118-1.2	T375M	Pathogenic	0.93
NPC1	O15118-1.2	T375N	Pathogenic	0.888
NPC1	O15118-1.2	T375P	Pathogenic	0.93
NPC1	O15118-1.2	T375Q	Pathogenic	0.937
NPC1	O15118-1.2	T375R	Pathogenic	0.933
NPC1	O15118-1.2	T375S	Pathogenic	0.879
NPC1	O15118-1.2	T375V	Pathogenic	0.89
NPC1	O15118-1.2	T375W	Pathogenic	0.947
NPC1	O15118-1.2	T375Y	Pathogenic	0.96
NPC1	O15118-1.2	N376A	Pathogenic	0.878
NPC1	O15118-1.2	N376C	Pathogenic	0.883
NPC1	O15118-1.2	N376D	Pathogenic	0.714
NPC1	O15118-1.2	N376E	Pathogenic	0.801
NPC1	O15118-1.2	N376F	Pathogenic	0.873
NPC1	O15118-1.2	N376G	Pathogenic	0.805
NPC1	O15118-1.2	N376H	Pathogenic	0.696
NPC1	O15118-1.2	N376I	Pathogenic	0.865
NPC1	O15118-1.2	N376K	Pathogenic	0.807
NPC1	O15118-1.2	N376L	Pathogenic	0.869
NPC1	O15118-1.2	N376M	Pathogenic	0.84
NPC1	O15118-1.2	N376P	Pathogenic	0.845
NPC1	O15118-1.2	N376Q	Pathogenic	0.787
NPC1	O15118-1.2	N376R	Pathogenic	0.819
NPC1	O15118-1.2	N376S	Pathogenic	0.709
NPC1	O15118-1.2	N376T	Pathogenic	0.743
NPC1	O15118-1.2	N376V	Pathogenic	0.874
NPC1	O15118-1.2	N376W	Pathogenic	0.911
NPC1	O15118-1.2	N376Y	Pathogenic	0.864
NPC1	O15118-1.2	P377A	Pathogenic	0.967
NPC1	O15118-1.2	P377C	Pathogenic	0.983
NPC1	O15118-1.2	P377D	Pathogenic	0.947
NPC1	O15118-1.2	P377E	Pathogenic	0.954
NPC1	O15118-1.2	P377F	Pathogenic	0.988
NPC1	O15118-1.2	P377G	Pathogenic	0.977
NPC1	O15118-1.2	P377H	Pathogenic	0.976
NPC1	O15118-1.2	P377I	Pathogenic	0.982
NPC1	O15118-1.2	P377K	Pathogenic	0.956
NPC1	O15118-1.2	P377L	Pathogenic	0.982
NPC1	O15118-1.2	P377M	Pathogenic	0.978
NPC1	O15118-1.2	P377N	Pathogenic	0.966
NPC1	O15118-1.2	P377Q	Pathogenic	0.961
NPC1	O15118-1.2	P377R	Pathogenic	0.972
NPC1	O15118-1.2	P377S	Pathogenic	0.962
NPC1	O15118-1.2	P377T	Pathogenic	0.962
NPC1	O15118-1.2	P377V	Pathogenic	0.975
NPC1	O15118-1.2	P377W	Pathogenic	0.989
NPC1	O15118-1.2	P377Y	Pathogenic	0.987
NPC1	O15118-1.2	V378A	Pathogenic	0.888
NPC1	O15118-1.2	V378C	Pathogenic	0.929
NPC1	O15118-1.2	V378D	Pathogenic	0.939
NPC1	O15118-1.2	V378E	Pathogenic	0.911
NPC1	O15118-1.2	V378F	Pathogenic	0.926
NPC1	O15118-1.2	V378G	Pathogenic	0.962
NPC1	O15118-1.2	V378H	Pathogenic	0.954
NPC1	O15118-1.2	V378I	Pathogenic	0.713
NPC1	O15118-1.2	V378K	Pathogenic	0.914
NPC1	O15118-1.2	V378L	Pathogenic	0.847
NPC1	O15118-1.2	V378M	Pathogenic	0.866
NPC1	O15118-1.2	V378N	Pathogenic	0.94
NPC1	O15118-1.2	V378P	Pathogenic	0.945
NPC1	O15118-1.2	V378Q	Pathogenic	0.924
NPC1	O15118-1.2	V378R	Pathogenic	0.944
NPC1	O15118-1.2	V378S	Pathogenic	0.937
NPC1	O15118-1.2	V378T	Pathogenic	0.87
NPC1	O15118-1.2	V378W	Pathogenic	0.965
NPC1	O15118-1.2	V378Y	Pathogenic	0.935
NPC1	O15118-1.2	D379A	Pathogenic	0.744
NPC1	O15118-1.2	D379C	Pathogenic	0.753
NPC1	O15118-1.2	D379E	Neutral	0.451
NPC1	O15118-1.2	D379F	Pathogenic	0.747
NPC1	O15118-1.2	D379G	Pathogenic	0.711
NPC1	O15118-1.2	D379H	Pathogenic	0.681
NPC1	O15118-1.2	D379I	Pathogenic	0.733
NPC1	O15118-1.2	D379K	Pathogenic	0.748
NPC1	O15118-1.2	D379L	Pathogenic	0.807
NPC1	O15118-1.2	D379M	Pathogenic	0.769
NPC1	O15118-1.2	D379N	Pathogenic	0.525
NPC1	O15118-1.2	D379P	Pathogenic	0.6
NPC1	O15118-1.2	D379Q	Pathogenic	0.614
NPC1	O15118-1.2	D379R	Pathogenic	0.825
NPC1	O15118-1.2	D379S	Pathogenic	0.593
NPC1	O15118-1.2	D379T	Pathogenic	0.638
NPC1	O15118-1.2	D379V	Pathogenic	0.749
NPC1	O15118-1.2	D379W	Pathogenic	0.815
NPC1	O15118-1.2	D379Y	Pathogenic	0.801
NPC1	O15118-1.2	L380A	Pathogenic	0.945
NPC1	O15118-1.2	L380C	Pathogenic	0.951
NPC1	O15118-1.2	L380D	Pathogenic	0.971
NPC1	O15118-1.2	L380E	Pathogenic	0.955
NPC1	O15118-1.2	L380F	Pathogenic	0.932
NPC1	O15118-1.2	L380G	Pathogenic	0.982
NPC1	O15118-1.2	L380H	Pathogenic	0.963
NPC1	O15118-1.2	L380I	Pathogenic	0.855
NPC1	O15118-1.2	L380K	Pathogenic	0.926
NPC1	O15118-1.2	L380M	Pathogenic	0.84
NPC1	O15118-1.2	L380N	Pathogenic	0.959
NPC1	O15118-1.2	L380P	Pathogenic	0.974
NPC1	O15118-1.2	L380Q	Pathogenic	0.941
NPC1	O15118-1.2	L380R	Pathogenic	0.931
NPC1	O15118-1.2	L380S	Pathogenic	0.956
NPC1	O15118-1.2	L380T	Pathogenic	0.936
NPC1	O15118-1.2	L380V	Pathogenic	0.896
NPC1	O15118-1.2	L380W	Pathogenic	0.968
NPC1	O15118-1.2	L380Y	Pathogenic	0.944
NPC1	O15118-1.2	W381A	Pathogenic	0.991
NPC1	O15118-1.2	W381C	Pathogenic	0.988
NPC1	O15118-1.2	W381D	Pathogenic	0.99
NPC1	O15118-1.2	W381E	Pathogenic	0.984
NPC1	O15118-1.2	W381F	Pathogenic	0.961
NPC1	O15118-1.2	W381G	Pathogenic	0.986
NPC1	O15118-1.2	W381H	Pathogenic	0.98
NPC1	O15118-1.2	W381I	Pathogenic	0.992
NPC1	O15118-1.2	W381K	Pathogenic	0.979
NPC1	O15118-1.2	W381L	Pathogenic	0.988
NPC1	O15118-1.2	W381M	Pathogenic	0.979
NPC1	O15118-1.2	W381N	Pathogenic	0.99
NPC1	O15118-1.2	W381P	Pathogenic	0.994
NPC1	O15118-1.2	W381Q	Pathogenic	0.979
NPC1	O15118-1.2	W381R	Pathogenic	0.977
NPC1	O15118-1.2	W381S	Pathogenic	0.989
NPC1	O15118-1.2	W381T	Pathogenic	0.984
NPC1	O15118-1.2	W381V	Pathogenic	0.991
NPC1	O15118-1.2	W381Y	Pathogenic	0.924
NPC1	O15118-1.2	S382A	Pathogenic	0.695
NPC1	O15118-1.2	S382C	Pathogenic	0.804
NPC1	O15118-1.2	S382D	Pathogenic	0.76
NPC1	O15118-1.2	S382E	Pathogenic	0.787
NPC1	O15118-1.2	S382F	Pathogenic	0.862
NPC1	O15118-1.2	S382G	Pathogenic	0.807
NPC1	O15118-1.2	S382H	Pathogenic	0.869
NPC1	O15118-1.2	S382I	Pathogenic	0.853
NPC1	O15118-1.2	S382K	Pathogenic	0.794
NPC1	O15118-1.2	S382L	Pathogenic	0.857
NPC1	O15118-1.2	S382M	Pathogenic	0.827
NPC1	O15118-1.2	S382N	Pathogenic	0.701
NPC1	O15118-1.2	S382P	Pathogenic	0.821
NPC1	O15118-1.2	S382Q	Pathogenic	0.814
NPC1	O15118-1.2	S382R	Pathogenic	0.859
NPC1	O15118-1.2	S382T	Pathogenic	0.716
NPC1	O15118-1.2	S382V	Pathogenic	0.863
NPC1	O15118-1.2	S382W	Pathogenic	0.903
NPC1	O15118-1.2	S382Y	Pathogenic	0.895
NPC1	O15118-1.2	A383C	Pathogenic	0.658
NPC1	O15118-1.2	A383D	Pathogenic	0.789
NPC1	O15118-1.2	A383E	Pathogenic	0.748
NPC1	O15118-1.2	A383F	Pathogenic	0.81
NPC1	O15118-1.2	A383G	Pathogenic	0.684
NPC1	O15118-1.2	A383H	Pathogenic	0.856
NPC1	O15118-1.2	A383I	Pathogenic	0.73
NPC1	O15118-1.2	A383K	Pathogenic	0.755
NPC1	O15118-1.2	A383L	Pathogenic	0.737
NPC1	O15118-1.2	A383M	Pathogenic	0.766
NPC1	O15118-1.2	A383N	Pathogenic	0.803
NPC1	O15118-1.2	A383P	Pathogenic	0.76
NPC1	O15118-1.2	A383Q	Pathogenic	0.778
NPC1	O15118-1.2	A383R	Pathogenic	0.769
NPC1	O15118-1.2	A383S	Pathogenic	0.574
NPC1	O15118-1.2	A383T	Pathogenic	0.711
NPC1	O15118-1.2	A383V	Pathogenic	0.666
NPC1	O15118-1.2	A383W	Pathogenic	0.865
NPC1	O15118-1.2	A383Y	Pathogenic	0.854
NPC1	O15118-1.2	P384A	Pathogenic	0.937
NPC1	O15118-1.2	P384C	Pathogenic	0.968
NPC1	O15118-1.2	P384D	Pathogenic	0.9
NPC1	O15118-1.2	P384E	Pathogenic	0.913
NPC1	O15118-1.2	P384F	Pathogenic	0.977
NPC1	O15118-1.2	P384G	Pathogenic	0.957
NPC1	O15118-1.2	P384H	Pathogenic	0.955
NPC1	O15118-1.2	P384I	Pathogenic	0.965
NPC1	O15118-1.2	P384K	Pathogenic	0.916
NPC1	O15118-1.2	P384L	Pathogenic	0.966
NPC1	O15118-1.2	P384M	Pathogenic	0.957
NPC1	O15118-1.2	P384N	Pathogenic	0.935
NPC1	O15118-1.2	P384Q	Pathogenic	0.926
NPC1	O15118-1.2	P384R	Pathogenic	0.946
NPC1	O15118-1.2	P384S	Pathogenic	0.927
NPC1	O15118-1.2	P384T	Pathogenic	0.928
NPC1	O15118-1.2	P384V	Pathogenic	0.953
NPC1	O15118-1.2	P384W	Pathogenic	0.978
NPC1	O15118-1.2	P384Y	Pathogenic	0.976
NPC1	O15118-1.2	S385A	Neutral	0.109
NPC1	O15118-1.2	S385C	Neutral	0.181
NPC1	O15118-1.2	S385D	Neutral	0.145
NPC1	O15118-1.2	S385E	Neutral	0.165
NPC1	O15118-1.2	S385F	Neutral	0.25
NPC1	O15118-1.2	S385G	Neutral	0.183
NPC1	O15118-1.2	S385H	Neutral	0.262
NPC1	O15118-1.2	S385I	Neutral	0.237
NPC1	O15118-1.2	S385K	Neutral	0.171
NPC1	O15118-1.2	S385L	Neutral	0.243
NPC1	O15118-1.2	S385M	Neutral	0.204
NPC1	O15118-1.2	S385N	Neutral	0.112
NPC1	O15118-1.2	S385P	Neutral	0.198
NPC1	O15118-1.2	S385Q	Neutral	0.19
NPC1	O15118-1.2	S385R	Neutral	0.246
NPC1	O15118-1.2	S385T	Neutral	0.119
NPC1	O15118-1.2	S385V	Neutral	0.252
NPC1	O15118-1.2	S385W	Neutral	0.333
NPC1	O15118-1.2	S385Y	Neutral	0.313
NPC1	O15118-1.2	S386A	Pathogenic	0.904
NPC1	O15118-1.2	S386C	Pathogenic	0.944
NPC1	O15118-1.2	S386D	Pathogenic	0.929
NPC1	O15118-1.2	S386E	Pathogenic	0.939
NPC1	O15118-1.2	S386F	Pathogenic	0.963
NPC1	O15118-1.2	S386G	Pathogenic	0.945
NPC1	O15118-1.2	S386H	Pathogenic	0.965
NPC1	O15118-1.2	S386I	Pathogenic	0.96
NPC1	O15118-1.2	S386K	Pathogenic	0.941
NPC1	O15118-1.2	S386L	Pathogenic	0.961
NPC1	O15118-1.2	S386M	Pathogenic	0.952
NPC1	O15118-1.2	S386N	Pathogenic	0.907
NPC1	O15118-1.2	S386P	Pathogenic	0.95
NPC1	O15118-1.2	S386Q	Pathogenic	0.948
NPC1	O15118-1.2	S386R	Pathogenic	0.962
NPC1	O15118-1.2	S386T	Pathogenic	0.913
NPC1	O15118-1.2	S386V	Pathogenic	0.963
NPC1	O15118-1.2	S386W	Pathogenic	0.975
NPC1	O15118-1.2	S386Y	Pathogenic	0.972
NPC1	O15118-1.2	Q387A	Pathogenic	0.84
NPC1	O15118-1.2	Q387C	Pathogenic	0.89
NPC1	O15118-1.2	Q387D	Pathogenic	0.754
NPC1	O15118-1.2	Q387E	Pathogenic	0.57
NPC1	O15118-1.2	Q387F	Pathogenic	0.856
NPC1	O15118-1.2	Q387G	Pathogenic	0.906
NPC1	O15118-1.2	Q387H	Pathogenic	0.745
NPC1	O15118-1.2	Q387I	Pathogenic	0.847
NPC1	O15118-1.2	Q387K	Pathogenic	0.657
NPC1	O15118-1.2	Q387L	Pathogenic	0.795
NPC1	O15118-1.2	Q387M	Pathogenic	0.677
NPC1	O15118-1.2	Q387N	Pathogenic	0.759
NPC1	O15118-1.2	Q387P	Pathogenic	0.799
NPC1	O15118-1.2	Q387R	Pathogenic	0.673
NPC1	O15118-1.2	Q387S	Pathogenic	0.794
NPC1	O15118-1.2	Q387T	Pathogenic	0.82
NPC1	O15118-1.2	Q387V	Pathogenic	0.819
NPC1	O15118-1.2	Q387W	Pathogenic	0.804
NPC1	O15118-1.2	Q387Y	Pathogenic	0.789
NPC1	O15118-1.2	A388C	Pathogenic	0.794
NPC1	O15118-1.2	A388D	Pathogenic	0.883
NPC1	O15118-1.2	A388E	Pathogenic	0.856
NPC1	O15118-1.2	A388F	Pathogenic	0.896
NPC1	O15118-1.2	A388G	Pathogenic	0.813
NPC1	O15118-1.2	A388H	Pathogenic	0.923
NPC1	O15118-1.2	A388I	Pathogenic	0.844
NPC1	O15118-1.2	A388K	Pathogenic	0.861
NPC1	O15118-1.2	A388L	Pathogenic	0.849
NPC1	O15118-1.2	A388M	Pathogenic	0.868
NPC1	O15118-1.2	A388N	Pathogenic	0.891
NPC1	O15118-1.2	A388P	Pathogenic	0.864
NPC1	O15118-1.2	A388Q	Pathogenic	0.876
NPC1	O15118-1.2	A388R	Pathogenic	0.87
NPC1	O15118-1.2	A388S	Pathogenic	0.73
NPC1	O15118-1.2	A388T	Pathogenic	0.832
NPC1	O15118-1.2	A388V	Pathogenic	0.8
NPC1	O15118-1.2	A388W	Pathogenic	0.928
NPC1	O15118-1.2	A388Y	Pathogenic	0.921
NPC1	O15118-1.2	R389A	Pathogenic	0.959
NPC1	O15118-1.2	R389C	Pathogenic	0.973
NPC1	O15118-1.2	R389D	Pathogenic	0.977
NPC1	O15118-1.2	R389E	Pathogenic	0.944
NPC1	O15118-1.2	R389F	Pathogenic	0.953
NPC1	O15118-1.2	R389G	Pathogenic	0.977
NPC1	O15118-1.2	R389H	Pathogenic	0.925
NPC1	O15118-1.2	R389I	Pathogenic	0.956
NPC1	O15118-1.2	R389K	Pathogenic	0.881
NPC1	O15118-1.2	R389L	Pathogenic	0.938
NPC1	O15118-1.2	R389M	Pathogenic	0.924
NPC1	O15118-1.2	R389N	Pathogenic	0.947
NPC1	O15118-1.2	R389P	Pathogenic	0.963
NPC1	O15118-1.2	R389Q	Pathogenic	0.906
NPC1	O15118-1.2	R389S	Pathogenic	0.962
NPC1	O15118-1.2	R389T	Pathogenic	0.953
NPC1	O15118-1.2	R389V	Pathogenic	0.967
NPC1	O15118-1.2	R389W	Pathogenic	0.946
NPC1	O15118-1.2	R389Y	Pathogenic	0.946
NPC1	O15118-1.2	L390A	Neutral	0.292
NPC1	O15118-1.2	L390C	Neutral	0.315
NPC1	O15118-1.2	L390D	Neutral	0.442
NPC1	O15118-1.2	L390E	Neutral	0.336
NPC1	O15118-1.2	L390F	Neutral	0.247
NPC1	O15118-1.2	L390G	Pathogenic	0.571
NPC1	O15118-1.2	L390H	Neutral	0.382
NPC1	O15118-1.2	L390I	Neutral	0.124
NPC1	O15118-1.2	L390K	Neutral	0.23
NPC1	O15118-1.2	L390M	Neutral	0.111
NPC1	O15118-1.2	L390N	Neutral	0.356
NPC1	O15118-1.2	L390P	Neutral	0.471
NPC1	O15118-1.2	L390Q	Neutral	0.277
NPC1	O15118-1.2	L390R	Neutral	0.243
NPC1	O15118-1.2	L390S	Neutral	0.343
NPC1	O15118-1.2	L390T	Neutral	0.257
NPC1	O15118-1.2	L390V	Neutral	0.17
NPC1	O15118-1.2	L390W	Neutral	0.419
NPC1	O15118-1.2	L390Y	Neutral	0.287
NPC1	O15118-1.2	E391A	Pathogenic	0.944
NPC1	O15118-1.2	E391C	Pathogenic	0.975
NPC1	O15118-1.2	E391D	Pathogenic	0.858
NPC1	O15118-1.2	E391F	Pathogenic	0.953
NPC1	O15118-1.2	E391G	Pathogenic	0.969
NPC1	O15118-1.2	E391H	Pathogenic	0.909
NPC1	O15118-1.2	E391I	Pathogenic	0.95
NPC1	O15118-1.2	E391K	Pathogenic	0.897
NPC1	O15118-1.2	E391L	Pathogenic	0.952
NPC1	O15118-1.2	E391M	Pathogenic	0.94
NPC1	O15118-1.2	E391N	Pathogenic	0.929
NPC1	O15118-1.2	E391P	Pathogenic	0.928
NPC1	O15118-1.2	E391Q	Pathogenic	0.836
NPC1	O15118-1.2	E391R	Pathogenic	0.932
NPC1	O15118-1.2	E391S	Pathogenic	0.926
NPC1	O15118-1.2	E391T	Pathogenic	0.937
NPC1	O15118-1.2	E391V	Pathogenic	0.936
NPC1	O15118-1.2	E391W	Pathogenic	0.954
NPC1	O15118-1.2	E391Y	Pathogenic	0.95
NPC1	O15118-1.2	K392A	Pathogenic	0.921
NPC1	O15118-1.2	K392C	Pathogenic	0.947
NPC1	O15118-1.2	K392D	Pathogenic	0.935
NPC1	O15118-1.2	K392E	Pathogenic	0.851
NPC1	O15118-1.2	K392F	Pathogenic	0.911
NPC1	O15118-1.2	K392G	Pathogenic	0.955
NPC1	O15118-1.2	K392H	Pathogenic	0.901
NPC1	O15118-1.2	K392I	Pathogenic	0.916
NPC1	O15118-1.2	K392L	Pathogenic	0.884
NPC1	O15118-1.2	K392M	Pathogenic	0.859
NPC1	O15118-1.2	K392N	Pathogenic	0.9
NPC1	O15118-1.2	K392P	Pathogenic	0.899
NPC1	O15118-1.2	K392Q	Pathogenic	0.829
NPC1	O15118-1.2	K392R	Pathogenic	0.801
NPC1	O15118-1.2	K392S	Pathogenic	0.896
NPC1	O15118-1.2	K392T	Pathogenic	0.91
NPC1	O15118-1.2	K392V	Pathogenic	0.91
NPC1	O15118-1.2	K392W	Pathogenic	0.912
NPC1	O15118-1.2	K392Y	Pathogenic	0.905
NPC1	O15118-1.2	E393A	Pathogenic	0.77
NPC1	O15118-1.2	E393C	Pathogenic	0.884
NPC1	O15118-1.2	E393D	Pathogenic	0.544
NPC1	O15118-1.2	E393F	Pathogenic	0.801
NPC1	O15118-1.2	E393G	Pathogenic	0.86
NPC1	O15118-1.2	E393H	Pathogenic	0.664
NPC1	O15118-1.2	E393I	Pathogenic	0.789
NPC1	O15118-1.2	E393K	Pathogenic	0.631
NPC1	O15118-1.2	E393L	Pathogenic	0.795
NPC1	O15118-1.2	E393M	Pathogenic	0.755
NPC1	O15118-1.2	E393N	Pathogenic	0.721
NPC1	O15118-1.2	E393P	Pathogenic	0.718
NPC1	O15118-1.2	E393Q	Pathogenic	0.501
NPC1	O15118-1.2	E393R	Pathogenic	0.731
NPC1	O15118-1.2	E393S	Pathogenic	0.711
NPC1	O15118-1.2	E393T	Pathogenic	0.744
NPC1	O15118-1.2	E393V	Pathogenic	0.743
NPC1	O15118-1.2	E393W	Pathogenic	0.803
NPC1	O15118-1.2	E393Y	Pathogenic	0.789
NPC1	O15118-1.2	Y394A	Pathogenic	0.938
NPC1	O15118-1.2	Y394C	Pathogenic	0.943
NPC1	O15118-1.2	Y394D	Pathogenic	0.931
NPC1	O15118-1.2	Y394E	Pathogenic	0.895
NPC1	O15118-1.2	Y394F	Pathogenic	0.578
NPC1	O15118-1.2	Y394G	Pathogenic	0.957
NPC1	O15118-1.2	Y394H	Pathogenic	0.691
NPC1	O15118-1.2	Y394I	Pathogenic	0.872
NPC1	O15118-1.2	Y394K	Pathogenic	0.866
NPC1	O15118-1.2	Y394L	Pathogenic	0.876
NPC1	O15118-1.2	Y394M	Pathogenic	0.892
NPC1	O15118-1.2	Y394N	Pathogenic	0.903
NPC1	O15118-1.2	Y394P	Pathogenic	0.957
NPC1	O15118-1.2	Y394Q	Pathogenic	0.866
NPC1	O15118-1.2	Y394R	Pathogenic	0.867
NPC1	O15118-1.2	Y394S	Pathogenic	0.928
NPC1	O15118-1.2	Y394T	Pathogenic	0.927
NPC1	O15118-1.2	Y394V	Pathogenic	0.903
NPC1	O15118-1.2	Y394W	Pathogenic	0.655
NPC1	O15118-1.2	F395A	Pathogenic	0.93
NPC1	O15118-1.2	F395C	Pathogenic	0.937
NPC1	O15118-1.2	F395D	Pathogenic	0.922
NPC1	O15118-1.2	F395E	Pathogenic	0.917
NPC1	O15118-1.2	F395G	Pathogenic	0.952
NPC1	O15118-1.2	F395H	Pathogenic	0.863
NPC1	O15118-1.2	F395I	Pathogenic	0.877
NPC1	O15118-1.2	F395K	Pathogenic	0.894
NPC1	O15118-1.2	F395L	Pathogenic	0.874
NPC1	O15118-1.2	F395M	Pathogenic	0.856
NPC1	O15118-1.2	F395N	Pathogenic	0.924
NPC1	O15118-1.2	F395P	Pathogenic	0.966
NPC1	O15118-1.2	F395Q	Pathogenic	0.925
NPC1	O15118-1.2	F395R	Pathogenic	0.901
NPC1	O15118-1.2	F395S	Pathogenic	0.92
NPC1	O15118-1.2	F395T	Pathogenic	0.918
NPC1	O15118-1.2	F395V	Pathogenic	0.907
NPC1	O15118-1.2	F395W	Pathogenic	0.822
NPC1	O15118-1.2	F395Y	Pathogenic	0.623
NPC1	O15118-1.2	D396A	Pathogenic	0.968
NPC1	O15118-1.2	D396C	Pathogenic	0.969
NPC1	O15118-1.2	D396E	Pathogenic	0.895
NPC1	O15118-1.2	D396F	Pathogenic	0.968
NPC1	O15118-1.2	D396G	Pathogenic	0.962
NPC1	O15118-1.2	D396H	Pathogenic	0.957
NPC1	O15118-1.2	D396I	Pathogenic	0.966
NPC1	O15118-1.2	D396K	Pathogenic	0.969
NPC1	O15118-1.2	D396L	Pathogenic	0.978
NPC1	O15118-1.2	D396M	Pathogenic	0.972
NPC1	O15118-1.2	D396N	Pathogenic	0.92
NPC1	O15118-1.2	D396P	Pathogenic	0.94
NPC1	O15118-1.2	D396Q	Pathogenic	0.943
NPC1	O15118-1.2	D396R	Pathogenic	0.98
NPC1	O15118-1.2	D396S	Pathogenic	0.938
NPC1	O15118-1.2	D396T	Pathogenic	0.948
NPC1	O15118-1.2	D396V	Pathogenic	0.969
NPC1	O15118-1.2	D396W	Pathogenic	0.979
NPC1	O15118-1.2	D396Y	Pathogenic	0.977
NPC1	O15118-1.2	Q397A	Neutral	0.441
NPC1	O15118-1.2	Q397C	Pathogenic	0.549
NPC1	O15118-1.2	Q397D	Neutral	0.315
NPC1	O15118-1.2	Q397E	Neutral	0.166
NPC1	O15118-1.2	Q397F	Neutral	0.471
NPC1	O15118-1.2	Q397G	Pathogenic	0.591
NPC1	O15118-1.2	Q397H	Neutral	0.305
NPC1	O15118-1.2	Q397I	Neutral	0.454
NPC1	O15118-1.2	Q397K	Neutral	0.223
NPC1	O15118-1.2	Q397L	Neutral	0.369
NPC1	O15118-1.2	Q397M	Neutral	0.24
NPC1	O15118-1.2	Q397N	Neutral	0.321
NPC1	O15118-1.2	Q397P	Neutral	0.375
NPC1	O15118-1.2	Q397R	Neutral	0.236
NPC1	O15118-1.2	Q397S	Neutral	0.367
NPC1	O15118-1.2	Q397T	Neutral	0.407
NPC1	O15118-1.2	Q397V	Neutral	0.405
NPC1	O15118-1.2	Q397W	Neutral	0.381
NPC1	O15118-1.2	Q397Y	Neutral	0.36
NPC1	O15118-1.2	H398A	Pathogenic	0.928
NPC1	O15118-1.2	H398C	Pathogenic	0.931
NPC1	O15118-1.2	H398D	Pathogenic	0.856
NPC1	O15118-1.2	H398E	Pathogenic	0.792
NPC1	O15118-1.2	H398F	Pathogenic	0.814
NPC1	O15118-1.2	H398G	Pathogenic	0.936
NPC1	O15118-1.2	H398I	Pathogenic	0.898
NPC1	O15118-1.2	H398K	Pathogenic	0.839
NPC1	O15118-1.2	H398L	Pathogenic	0.901
NPC1	O15118-1.2	H398M	Pathogenic	0.878
NPC1	O15118-1.2	H398N	Pathogenic	0.739
NPC1	O15118-1.2	H398P	Pathogenic	0.907
NPC1	O15118-1.2	H398Q	Pathogenic	0.809
NPC1	O15118-1.2	H398R	Pathogenic	0.792
NPC1	O15118-1.2	H398S	Pathogenic	0.895
NPC1	O15118-1.2	H398T	Pathogenic	0.918
NPC1	O15118-1.2	H398V	Pathogenic	0.918
NPC1	O15118-1.2	H398W	Pathogenic	0.867
NPC1	O15118-1.2	H398Y	Pathogenic	0.652
NPC1	O15118-1.2	F399A	Pathogenic	0.972
NPC1	O15118-1.2	F399C	Pathogenic	0.974
NPC1	O15118-1.2	F399D	Pathogenic	0.968
NPC1	O15118-1.2	F399E	Pathogenic	0.966
NPC1	O15118-1.2	F399G	Pathogenic	0.981
NPC1	O15118-1.2	F399H	Pathogenic	0.942
NPC1	O15118-1.2	F399I	Pathogenic	0.948
NPC1	O15118-1.2	F399K	Pathogenic	0.956
NPC1	O15118-1.2	F399L	Pathogenic	0.947
NPC1	O15118-1.2	F399M	Pathogenic	0.938
NPC1	O15118-1.2	F399N	Pathogenic	0.969
NPC1	O15118-1.2	F399P	Pathogenic	0.987
NPC1	O15118-1.2	F399Q	Pathogenic	0.969
NPC1	O15118-1.2	F399R	Pathogenic	0.959
NPC1	O15118-1.2	F399S	Pathogenic	0.967
NPC1	O15118-1.2	F399T	Pathogenic	0.966
NPC1	O15118-1.2	F399V	Pathogenic	0.962
NPC1	O15118-1.2	F399W	Pathogenic	0.922
NPC1	O15118-1.2	F399Y	Pathogenic	0.809
NPC1	O15118-1.2	G400A	Pathogenic	0.537
NPC1	O15118-1.2	G400C	Pathogenic	0.768
NPC1	O15118-1.2	G400D	Pathogenic	0.628
NPC1	O15118-1.2	G400E	Pathogenic	0.743
NPC1	O15118-1.2	G400F	Pathogenic	0.773
NPC1	O15118-1.2	G400H	Pathogenic	0.783
NPC1	O15118-1.2	G400I	Pathogenic	0.823
NPC1	O15118-1.2	G400K	Pathogenic	0.751
NPC1	O15118-1.2	G400L	Pathogenic	0.828
NPC1	O15118-1.2	G400M	Pathogenic	0.793
NPC1	O15118-1.2	G400N	Pathogenic	0.556
NPC1	O15118-1.2	G400P	Pathogenic	0.715
NPC1	O15118-1.2	G400Q	Pathogenic	0.774
NPC1	O15118-1.2	G400R	Pathogenic	0.765
NPC1	O15118-1.2	G400S	Pathogenic	0.568
NPC1	O15118-1.2	G400T	Pathogenic	0.749
NPC1	O15118-1.2	G400V	Pathogenic	0.774
NPC1	O15118-1.2	G400W	Pathogenic	0.701
NPC1	O15118-1.2	G400Y	Pathogenic	0.823
NPC1	O15118-1.2	P401A	Pathogenic	0.966
NPC1	O15118-1.2	P401C	Pathogenic	0.983
NPC1	O15118-1.2	P401D	Pathogenic	0.945
NPC1	O15118-1.2	P401E	Pathogenic	0.953
NPC1	O15118-1.2	P401F	Pathogenic	0.988
NPC1	O15118-1.2	P401G	Pathogenic	0.977
NPC1	O15118-1.2	P401H	Pathogenic	0.976
NPC1	O15118-1.2	P401I	Pathogenic	0.981
NPC1	O15118-1.2	P401K	Pathogenic	0.954
NPC1	O15118-1.2	P401L	Pathogenic	0.982
NPC1	O15118-1.2	P401M	Pathogenic	0.977
NPC1	O15118-1.2	P401N	Pathogenic	0.965
NPC1	O15118-1.2	P401Q	Pathogenic	0.96
NPC1	O15118-1.2	P401R	Pathogenic	0.971
NPC1	O15118-1.2	P401S	Pathogenic	0.96
NPC1	O15118-1.2	P401T	Pathogenic	0.961
NPC1	O15118-1.2	P401V	Pathogenic	0.975
NPC1	O15118-1.2	P401W	Pathogenic	0.988
NPC1	O15118-1.2	P401Y	Pathogenic	0.987
NPC1	O15118-1.2	F402A	Pathogenic	0.972
NPC1	O15118-1.2	F402C	Pathogenic	0.974
NPC1	O15118-1.2	F402D	Pathogenic	0.968
NPC1	O15118-1.2	F402E	Pathogenic	0.966
NPC1	O15118-1.2	F402G	Pathogenic	0.981
NPC1	O15118-1.2	F402H	Pathogenic	0.942
NPC1	O15118-1.2	F402I	Pathogenic	0.948
NPC1	O15118-1.2	F402K	Pathogenic	0.956
NPC1	O15118-1.2	F402L	Pathogenic	0.947
NPC1	O15118-1.2	F402M	Pathogenic	0.938
NPC1	O15118-1.2	F402N	Pathogenic	0.969
NPC1	O15118-1.2	F402P	Pathogenic	0.987
NPC1	O15118-1.2	F402Q	Pathogenic	0.969
NPC1	O15118-1.2	F402R	Pathogenic	0.959
NPC1	O15118-1.2	F402S	Pathogenic	0.967
NPC1	O15118-1.2	F402T	Pathogenic	0.966
NPC1	O15118-1.2	F402V	Pathogenic	0.962
NPC1	O15118-1.2	F402W	Pathogenic	0.922
NPC1	O15118-1.2	F402Y	Pathogenic	0.809
NPC1	O15118-1.2	F403A	Pathogenic	0.872
NPC1	O15118-1.2	F403C	Pathogenic	0.884
NPC1	O15118-1.2	F403D	Pathogenic	0.859
NPC1	O15118-1.2	F403E	Pathogenic	0.851
NPC1	O15118-1.2	F403G	Pathogenic	0.911
NPC1	O15118-1.2	F403H	Pathogenic	0.763
NPC1	O15118-1.2	F403I	Pathogenic	0.785
NPC1	O15118-1.2	F403K	Pathogenic	0.812
NPC1	O15118-1.2	F403L	Pathogenic	0.781
NPC1	O15118-1.2	F403M	Pathogenic	0.753
NPC1	O15118-1.2	F403N	Pathogenic	0.862
NPC1	O15118-1.2	F403P	Pathogenic	0.937
NPC1	O15118-1.2	F403Q	Pathogenic	0.864
NPC1	O15118-1.2	F403R	Pathogenic	0.823
NPC1	O15118-1.2	F403S	Pathogenic	0.855
NPC1	O15118-1.2	F403T	Pathogenic	0.852
NPC1	O15118-1.2	F403V	Pathogenic	0.833
NPC1	O15118-1.2	F403W	Pathogenic	0.703
NPC1	O15118-1.2	F403Y	Neutral	0.459
NPC1	O15118-1.2	R404A	Pathogenic	0.972
NPC1	O15118-1.2	R404C	Pathogenic	0.981
NPC1	O15118-1.2	R404D	Pathogenic	0.984
NPC1	O15118-1.2	R404E	Pathogenic	0.961
NPC1	O15118-1.2	R404F	Pathogenic	0.968
NPC1	O15118-1.2	R404G	Pathogenic	0.984
NPC1	O15118-1.2	R404H	Pathogenic	0.948
NPC1	O15118-1.2	R404I	Pathogenic	0.97
NPC1	O15118-1.2	R404K	Pathogenic	0.917
NPC1	O15118-1.2	R404L	Pathogenic	0.958
NPC1	O15118-1.2	R404M	Pathogenic	0.947
NPC1	O15118-1.2	R404N	Pathogenic	0.964
NPC1	O15118-1.2	R404P	Pathogenic	0.975
NPC1	O15118-1.2	R404Q	Pathogenic	0.935
NPC1	O15118-1.2	R404S	Pathogenic	0.974
NPC1	O15118-1.2	R404T	Pathogenic	0.968
NPC1	O15118-1.2	R404V	Pathogenic	0.978
NPC1	O15118-1.2	R404W	Pathogenic	0.963
NPC1	O15118-1.2	R404Y	Pathogenic	0.963
NPC1	O15118-1.2	T405A	Pathogenic	0.774
NPC1	O15118-1.2	T405C	Pathogenic	0.782
NPC1	O15118-1.2	T405D	Pathogenic	0.759
NPC1	O15118-1.2	T405E	Pathogenic	0.781
NPC1	O15118-1.2	T405F	Pathogenic	0.833
NPC1	O15118-1.2	T405G	Pathogenic	0.886
NPC1	O15118-1.2	T405H	Pathogenic	0.878
NPC1	O15118-1.2	T405I	Pathogenic	0.759
NPC1	O15118-1.2	T405K	Pathogenic	0.788
NPC1	O15118-1.2	T405L	Pathogenic	0.765
NPC1	O15118-1.2	T405M	Pathogenic	0.792
NPC1	O15118-1.2	T405N	Pathogenic	0.695
NPC1	O15118-1.2	T405P	Pathogenic	0.792
NPC1	O15118-1.2	T405Q	Pathogenic	0.809
NPC1	O15118-1.2	T405R	Pathogenic	0.8
NPC1	O15118-1.2	T405S	Pathogenic	0.674
NPC1	O15118-1.2	T405V	Pathogenic	0.699
NPC1	O15118-1.2	T405W	Pathogenic	0.835
NPC1	O15118-1.2	T405Y	Pathogenic	0.872
NPC1	O15118-1.2	E406A	Pathogenic	0.901
NPC1	O15118-1.2	E406C	Pathogenic	0.954
NPC1	O15118-1.2	E406D	Pathogenic	0.764
NPC1	O15118-1.2	E406F	Pathogenic	0.916
NPC1	O15118-1.2	E406G	Pathogenic	0.943
NPC1	O15118-1.2	E406H	Pathogenic	0.843
NPC1	O15118-1.2	E406I	Pathogenic	0.91
NPC1	O15118-1.2	E406K	Pathogenic	0.823
NPC1	O15118-1.2	E406L	Pathogenic	0.913
NPC1	O15118-1.2	E406M	Pathogenic	0.893
NPC1	O15118-1.2	E406N	Pathogenic	0.875
NPC1	O15118-1.2	E406P	Pathogenic	0.873
NPC1	O15118-1.2	E406Q	Pathogenic	0.731
NPC1	O15118-1.2	E406R	Pathogenic	0.88
NPC1	O15118-1.2	E406S	Pathogenic	0.87
NPC1	O15118-1.2	E406T	Pathogenic	0.888
NPC1	O15118-1.2	E406V	Pathogenic	0.887
NPC1	O15118-1.2	E406W	Pathogenic	0.917
NPC1	O15118-1.2	E406Y	Pathogenic	0.91
NPC1	O15118-1.2	Q407A	Pathogenic	0.972
NPC1	O15118-1.2	Q407C	Pathogenic	0.982
NPC1	O15118-1.2	Q407D	Pathogenic	0.953
NPC1	O15118-1.2	Q407E	Pathogenic	0.897
NPC1	O15118-1.2	Q407F	Pathogenic	0.975
NPC1	O15118-1.2	Q407G	Pathogenic	0.984
NPC1	O15118-1.2	Q407H	Pathogenic	0.95
NPC1	O15118-1.2	Q407I	Pathogenic	0.973
NPC1	O15118-1.2	Q407K	Pathogenic	0.926
NPC1	O15118-1.2	Q407L	Pathogenic	0.962
NPC1	O15118-1.2	Q407M	Pathogenic	0.932
NPC1	O15118-1.2	Q407N	Pathogenic	0.954
NPC1	O15118-1.2	Q407P	Pathogenic	0.963
NPC1	O15118-1.2	Q407R	Pathogenic	0.931
NPC1	O15118-1.2	Q407S	Pathogenic	0.962
NPC1	O15118-1.2	Q407T	Pathogenic	0.968
NPC1	O15118-1.2	Q407V	Pathogenic	0.968
NPC1	O15118-1.2	Q407W	Pathogenic	0.964
NPC1	O15118-1.2	Q407Y	Pathogenic	0.961
NPC1	O15118-1.2	L408A	Pathogenic	0.74
NPC1	O15118-1.2	L408C	Pathogenic	0.761
NPC1	O15118-1.2	L408D	Pathogenic	0.846
NPC1	O15118-1.2	L408E	Pathogenic	0.778
NPC1	O15118-1.2	L408F	Pathogenic	0.694
NPC1	O15118-1.2	L408G	Pathogenic	0.902
NPC1	O15118-1.2	L408H	Pathogenic	0.81
NPC1	O15118-1.2	L408I	Neutral	0.494
NPC1	O15118-1.2	L408K	Pathogenic	0.674
NPC1	O15118-1.2	L408M	Neutral	0.463
NPC1	O15118-1.2	L408N	Pathogenic	0.793
NPC1	O15118-1.2	L408P	Pathogenic	0.86
NPC1	O15118-1.2	L408Q	Pathogenic	0.726
NPC1	O15118-1.2	L408R	Pathogenic	0.69
NPC1	O15118-1.2	L408S	Pathogenic	0.783
NPC1	O15118-1.2	L408T	Pathogenic	0.706
NPC1	O15118-1.2	L408V	Pathogenic	0.586
NPC1	O15118-1.2	L408W	Pathogenic	0.833
NPC1	O15118-1.2	L408Y	Pathogenic	0.736
NPC1	O15118-1.2	I409A	Pathogenic	0.95
NPC1	O15118-1.2	I409C	Pathogenic	0.955
NPC1	O15118-1.2	I409D	Pathogenic	0.961
NPC1	O15118-1.2	I409E	Pathogenic	0.959
NPC1	O15118-1.2	I409F	Pathogenic	0.941
NPC1	O15118-1.2	I409G	Pathogenic	0.984
NPC1	O15118-1.2	I409H	Pathogenic	0.966
NPC1	O15118-1.2	I409K	Pathogenic	0.953
NPC1	O15118-1.2	I409L	Pathogenic	0.87
NPC1	O15118-1.2	I409M	Pathogenic	0.894
NPC1	O15118-1.2	I409N	Pathogenic	0.962
NPC1	O15118-1.2	I409P	Pathogenic	0.976
NPC1	O15118-1.2	I409Q	Pathogenic	0.963
NPC1	O15118-1.2	I409R	Pathogenic	0.956
NPC1	O15118-1.2	I409S	Pathogenic	0.96
NPC1	O15118-1.2	I409T	Pathogenic	0.941
NPC1	O15118-1.2	I409V	Pathogenic	0.813
NPC1	O15118-1.2	I409W	Pathogenic	0.981
NPC1	O15118-1.2	I409Y	Pathogenic	0.949
NPC1	O15118-1.2	I410A	Pathogenic	0.91
NPC1	O15118-1.2	I410C	Pathogenic	0.918
NPC1	O15118-1.2	I410D	Pathogenic	0.93
NPC1	O15118-1.2	I410E	Pathogenic	0.925
NPC1	O15118-1.2	I410F	Pathogenic	0.895
NPC1	O15118-1.2	I410G	Pathogenic	0.97
NPC1	O15118-1.2	I410H	Pathogenic	0.938
NPC1	O15118-1.2	I410K	Pathogenic	0.915
NPC1	O15118-1.2	I410L	Pathogenic	0.781
NPC1	O15118-1.2	I410M	Pathogenic	0.818
NPC1	O15118-1.2	I410N	Pathogenic	0.931
NPC1	O15118-1.2	I410P	Pathogenic	0.956
NPC1	O15118-1.2	I410Q	Pathogenic	0.932
NPC1	O15118-1.2	I410R	Pathogenic	0.92
NPC1	O15118-1.2	I410S	Pathogenic	0.927
NPC1	O15118-1.2	I410T	Pathogenic	0.895
NPC1	O15118-1.2	I410V	Pathogenic	0.699
NPC1	O15118-1.2	I410W	Pathogenic	0.965
NPC1	O15118-1.2	I410Y	Pathogenic	0.908
NPC1	O15118-1.2	R411A	Neutral	0.483
NPC1	O15118-1.2	R411C	Pathogenic	0.59
NPC1	O15118-1.2	R411D	Pathogenic	0.63
NPC1	O15118-1.2	R411E	Neutral	0.403
NPC1	O15118-1.2	R411F	Neutral	0.45
NPC1	O15118-1.2	R411G	Pathogenic	0.631
NPC1	O15118-1.2	R411H	Neutral	0.331
NPC1	O15118-1.2	R411I	Neutral	0.466
NPC1	O15118-1.2	R411K	Neutral	0.231
NPC1	O15118-1.2	R411L	Neutral	0.38
NPC1	O15118-1.2	R411M	Neutral	0.328
NPC1	O15118-1.2	R411N	Neutral	0.419
NPC1	O15118-1.2	R411P	Pathogenic	0.511
NPC1	O15118-1.2	R411Q	Neutral	0.279
NPC1	O15118-1.2	R411S	Pathogenic	0.503
NPC1	O15118-1.2	R411T	Neutral	0.448
NPC1	O15118-1.2	R411V	Pathogenic	0.543
NPC1	O15118-1.2	R411W	Neutral	0.416
NPC1	O15118-1.2	R411Y	Neutral	0.414
NPC1	O15118-1.2	A412C	Pathogenic	0.67
NPC1	O15118-1.2	A412D	Pathogenic	0.799
NPC1	O15118-1.2	A412E	Pathogenic	0.759
NPC1	O15118-1.2	A412F	Pathogenic	0.819
NPC1	O15118-1.2	A412G	Pathogenic	0.697
NPC1	O15118-1.2	A412H	Pathogenic	0.863
NPC1	O15118-1.2	A412I	Pathogenic	0.741
NPC1	O15118-1.2	A412K	Pathogenic	0.766
NPC1	O15118-1.2	A412L	Pathogenic	0.748
NPC1	O15118-1.2	A412M	Pathogenic	0.776
NPC1	O15118-1.2	A412N	Pathogenic	0.812
NPC1	O15118-1.2	A412P	Pathogenic	0.77
NPC1	O15118-1.2	A412Q	Pathogenic	0.788
NPC1	O15118-1.2	A412R	Pathogenic	0.779
NPC1	O15118-1.2	A412S	Pathogenic	0.588
NPC1	O15118-1.2	A412T	Pathogenic	0.723
NPC1	O15118-1.2	A412V	Pathogenic	0.679
NPC1	O15118-1.2	A412W	Pathogenic	0.871
NPC1	O15118-1.2	A412Y	Pathogenic	0.861
NPC1	O15118-1.2	P413A	Pathogenic	0.601
NPC1	O15118-1.2	P413C	Pathogenic	0.753
NPC1	O15118-1.2	P413D	Neutral	0.48
NPC1	O15118-1.2	P413E	Pathogenic	0.518
NPC1	O15118-1.2	P413F	Pathogenic	0.815
NPC1	O15118-1.2	P413G	Pathogenic	0.692
NPC1	O15118-1.2	P413H	Pathogenic	0.683
NPC1	O15118-1.2	P413I	Pathogenic	0.736
NPC1	O15118-1.2	P413K	Pathogenic	0.528
NPC1	O15118-1.2	P413L	Pathogenic	0.742
NPC1	O15118-1.2	P413M	Pathogenic	0.696
NPC1	O15118-1.2	P413N	Pathogenic	0.596
NPC1	O15118-1.2	P413Q	Pathogenic	0.56
NPC1	O15118-1.2	P413R	Pathogenic	0.639
NPC1	O15118-1.2	P413S	Pathogenic	0.564
NPC1	O15118-1.2	P413T	Pathogenic	0.568
NPC1	O15118-1.2	P413V	Pathogenic	0.672
NPC1	O15118-1.2	P413W	Pathogenic	0.817
NPC1	O15118-1.2	P413Y	Pathogenic	0.803
NPC1	O15118-1.2	L414A	Neutral	0.145
NPC1	O15118-1.2	L414C	Neutral	0.16
NPC1	O15118-1.2	L414D	Neutral	0.247
NPC1	O15118-1.2	L414E	Neutral	0.173
NPC1	O15118-1.2	L414F	Neutral	0.119
NPC1	O15118-1.2	L414G	Neutral	0.354
NPC1	O15118-1.2	L414H	Neutral	0.203
NPC1	O15118-1.2	L414I	Neutral	0.055
NPC1	O15118-1.2	L414K	Neutral	0.11
NPC1	O15118-1.2	L414M	Neutral	0.049
NPC1	O15118-1.2	L414N	Neutral	0.186
NPC1	O15118-1.2	L414P	Neutral	0.269
NPC1	O15118-1.2	L414Q	Neutral	0.137
NPC1	O15118-1.2	L414R	Neutral	0.117
NPC1	O15118-1.2	L414S	Neutral	0.177
NPC1	O15118-1.2	L414T	Neutral	0.125
NPC1	O15118-1.2	L414V	Neutral	0.078
NPC1	O15118-1.2	L414W	Neutral	0.229
NPC1	O15118-1.2	L414Y	Neutral	0.142
NPC1	O15118-1.2	T415A	Neutral	0.228
NPC1	O15118-1.2	T415C	Neutral	0.236
NPC1	O15118-1.2	T415D	Neutral	0.214
NPC1	O15118-1.2	T415E	Neutral	0.236
NPC1	O15118-1.2	T415F	Neutral	0.301
NPC1	O15118-1.2	T415G	Neutral	0.401
NPC1	O15118-1.2	T415H	Neutral	0.383
NPC1	O15118-1.2	T415I	Neutral	0.214
NPC1	O15118-1.2	T415K	Neutral	0.244
NPC1	O15118-1.2	T415L	Neutral	0.22
NPC1	O15118-1.2	T415M	Neutral	0.248
NPC1	O15118-1.2	T415N	Neutral	0.164
NPC1	O15118-1.2	T415P	Neutral	0.248
NPC1	O15118-1.2	T415Q	Neutral	0.268
NPC1	O15118-1.2	T415R	Neutral	0.257
NPC1	O15118-1.2	T415S	Neutral	0.152
NPC1	O15118-1.2	T415V	Neutral	0.167
NPC1	O15118-1.2	T415W	Neutral	0.304
NPC1	O15118-1.2	T415Y	Neutral	0.37
NPC1	O15118-1.2	D416A	Neutral	0.195
NPC1	O15118-1.2	D416C	Neutral	0.202
NPC1	O15118-1.2	D416E	Neutral	0.064
NPC1	O15118-1.2	D416F	Neutral	0.197
NPC1	O15118-1.2	D416G	Neutral	0.17
NPC1	O15118-1.2	D416H	Neutral	0.151
NPC1	O15118-1.2	D416I	Neutral	0.186
NPC1	O15118-1.2	D416K	Neutral	0.198
NPC1	O15118-1.2	D416L	Neutral	0.258
NPC1	O15118-1.2	D416M	Neutral	0.217
NPC1	O15118-1.2	D416N	Neutral	0.084
NPC1	O15118-1.2	D416P	Neutral	0.111
NPC1	O15118-1.2	D416Q	Neutral	0.117
NPC1	O15118-1.2	D416R	Neutral	0.281
NPC1	O15118-1.2	D416S	Neutral	0.108
NPC1	O15118-1.2	D416T	Neutral	0.128
NPC1	O15118-1.2	D416V	Neutral	0.198
NPC1	O15118-1.2	D416W	Neutral	0.268
NPC1	O15118-1.2	D416Y	Neutral	0.251
NPC1	O15118-1.2	K417A	Neutral	0.131
NPC1	O15118-1.2	K417C	Neutral	0.188
NPC1	O15118-1.2	K417D	Neutral	0.157
NPC1	O15118-1.2	K417E	Neutral	0.069
NPC1	O15118-1.2	K417F	Neutral	0.117
NPC1	O15118-1.2	K417G	Neutral	0.216
NPC1	O15118-1.2	K417H	Neutral	0.105
NPC1	O15118-1.2	K417I	Neutral	0.123
NPC1	O15118-1.2	K417L	Neutral	0.09
NPC1	O15118-1.2	K417M	Neutral	0.073
NPC1	O15118-1.2	K417N	Neutral	0.104
NPC1	O15118-1.2	K417P	Neutral	0.103
NPC1	O15118-1.2	K417Q	Neutral	0.059
NPC1	O15118-1.2	K417R	Neutral	0.049
NPC1	O15118-1.2	K417S	Neutral	0.1
NPC1	O15118-1.2	K417T	Neutral	0.116
NPC1	O15118-1.2	K417V	Neutral	0.115
NPC1	O15118-1.2	K417W	Neutral	0.118
NPC1	O15118-1.2	K417Y	Neutral	0.109
NPC1	O15118-1.2	H418A	Pathogenic	0.626
NPC1	O15118-1.2	H418C	Pathogenic	0.637
NPC1	O15118-1.2	H418D	Neutral	0.436
NPC1	O15118-1.2	H418E	Neutral	0.33
NPC1	O15118-1.2	H418F	Neutral	0.362
NPC1	O15118-1.2	H418G	Pathogenic	0.656
NPC1	O15118-1.2	H418I	Pathogenic	0.533
NPC1	O15118-1.2	H418K	Neutral	0.404
NPC1	O15118-1.2	H418L	Pathogenic	0.541
NPC1	O15118-1.2	H418M	Neutral	0.484
NPC1	O15118-1.2	H418N	Neutral	0.268
NPC1	O15118-1.2	H418P	Pathogenic	0.56
NPC1	O15118-1.2	H418Q	Neutral	0.355
NPC1	O15118-1.2	H418R	Neutral	0.331
NPC1	O15118-1.2	H418S	Pathogenic	0.524
NPC1	O15118-1.2	H418T	Pathogenic	0.593
NPC1	O15118-1.2	H418V	Pathogenic	0.591
NPC1	O15118-1.2	H418W	Neutral	0.458
NPC1	O15118-1.2	H418Y	Neutral	0.196
NPC1	O15118-1.2	I419A	Neutral	0.341
NPC1	O15118-1.2	I419C	Neutral	0.366
NPC1	O15118-1.2	I419D	Neutral	0.404
NPC1	O15118-1.2	I419E	Neutral	0.388
NPC1	O15118-1.2	I419F	Neutral	0.304
NPC1	O15118-1.2	I419G	Pathogenic	0.625
NPC1	O15118-1.2	I419H	Neutral	0.437
NPC1	O15118-1.2	I419K	Neutral	0.355
NPC1	O15118-1.2	I419L	Neutral	0.155
NPC1	O15118-1.2	I419M	Neutral	0.187
NPC1	O15118-1.2	I419N	Neutral	0.41
NPC1	O15118-1.2	I419P	Pathogenic	0.528
NPC1	O15118-1.2	I419Q	Neutral	0.414
NPC1	O15118-1.2	I419R	Neutral	0.372
NPC1	O15118-1.2	I419S	Neutral	0.396
NPC1	O15118-1.2	I419T	Neutral	0.303
NPC1	O15118-1.2	I419V	Neutral	0.106
NPC1	O15118-1.2	I419W	Pathogenic	0.587
NPC1	O15118-1.2	I419Y	Neutral	0.335
NPC1	O15118-1.2	Y420A	Pathogenic	0.81
NPC1	O15118-1.2	Y420C	Pathogenic	0.825
NPC1	O15118-1.2	Y420D	Pathogenic	0.792
NPC1	O15118-1.2	Y420E	Pathogenic	0.708
NPC1	O15118-1.2	Y420F	Neutral	0.28
NPC1	O15118-1.2	Y420G	Pathogenic	0.864
NPC1	O15118-1.2	Y420H	Neutral	0.388
NPC1	O15118-1.2	Y420I	Pathogenic	0.659
NPC1	O15118-1.2	Y420K	Pathogenic	0.648
NPC1	O15118-1.2	Y420L	Pathogenic	0.667
NPC1	O15118-1.2	Y420M	Pathogenic	0.7
NPC1	O15118-1.2	Y420N	Pathogenic	0.726
NPC1	O15118-1.2	Y420P	Pathogenic	0.863
NPC1	O15118-1.2	Y420Q	Pathogenic	0.647
NPC1	O15118-1.2	Y420R	Pathogenic	0.648
NPC1	O15118-1.2	Y420S	Pathogenic	0.786
NPC1	O15118-1.2	Y420T	Pathogenic	0.782
NPC1	O15118-1.2	Y420V	Pathogenic	0.725
NPC1	O15118-1.2	Y420W	Neutral	0.351
NPC1	O15118-1.2	Q421A	Neutral	0.277
NPC1	O15118-1.2	Q421C	Neutral	0.371
NPC1	O15118-1.2	Q421D	Neutral	0.183
NPC1	O15118-1.2	Q421E	Neutral	0.088
NPC1	O15118-1.2	Q421F	Neutral	0.302
NPC1	O15118-1.2	Q421G	Neutral	0.412
NPC1	O15118-1.2	Q421H	Neutral	0.176
NPC1	O15118-1.2	Q421I	Neutral	0.287
NPC1	O15118-1.2	Q421K	Neutral	0.123
NPC1	O15118-1.2	Q421L	Neutral	0.221
NPC1	O15118-1.2	Q421M	Neutral	0.133
NPC1	O15118-1.2	Q421N	Neutral	0.187
NPC1	O15118-1.2	Q421P	Neutral	0.225
NPC1	O15118-1.2	Q421R	Neutral	0.131
NPC1	O15118-1.2	Q421S	Neutral	0.22
NPC1	O15118-1.2	Q421T	Neutral	0.25
NPC1	O15118-1.2	Q421V	Neutral	0.249
NPC1	O15118-1.2	Q421W	Neutral	0.23
NPC1	O15118-1.2	Q421Y	Neutral	0.215
NPC1	O15118-1.2	P422A	Pathogenic	0.69
NPC1	O15118-1.2	P422C	Pathogenic	0.819
NPC1	O15118-1.2	P422D	Pathogenic	0.577
NPC1	O15118-1.2	P422E	Pathogenic	0.614
NPC1	O15118-1.2	P422F	Pathogenic	0.867
NPC1	O15118-1.2	P422G	Pathogenic	0.769
NPC1	O15118-1.2	P422H	Pathogenic	0.761
NPC1	O15118-1.2	P422I	Pathogenic	0.805
NPC1	O15118-1.2	P422K	Pathogenic	0.623
NPC1	O15118-1.2	P422L	Pathogenic	0.81
NPC1	O15118-1.2	P422M	Pathogenic	0.772
NPC1	O15118-1.2	P422N	Pathogenic	0.686
NPC1	O15118-1.2	P422Q	Pathogenic	0.653
NPC1	O15118-1.2	P422R	Pathogenic	0.724
NPC1	O15118-1.2	P422S	Pathogenic	0.657
NPC1	O15118-1.2	P422T	Pathogenic	0.66
NPC1	O15118-1.2	P422V	Pathogenic	0.752
NPC1	O15118-1.2	P422W	Pathogenic	0.869
NPC1	O15118-1.2	P422Y	Pathogenic	0.858
NPC1	O15118-1.2	Y423A	Pathogenic	0.752
NPC1	O15118-1.2	Y423C	Pathogenic	0.769
NPC1	O15118-1.2	Y423D	Pathogenic	0.73
NPC1	O15118-1.2	Y423E	Pathogenic	0.632
NPC1	O15118-1.2	Y423F	Neutral	0.216
NPC1	O15118-1.2	Y423G	Pathogenic	0.819
NPC1	O15118-1.2	Y423H	Neutral	0.31
NPC1	O15118-1.2	Y423I	Pathogenic	0.579
NPC1	O15118-1.2	Y423K	Pathogenic	0.567
NPC1	O15118-1.2	Y423L	Pathogenic	0.587
NPC1	O15118-1.2	Y423M	Pathogenic	0.624
NPC1	O15118-1.2	Y423N	Pathogenic	0.653
NPC1	O15118-1.2	Y423P	Pathogenic	0.817
NPC1	O15118-1.2	Y423Q	Pathogenic	0.566
NPC1	O15118-1.2	Y423R	Pathogenic	0.567
NPC1	O15118-1.2	Y423S	Pathogenic	0.723
NPC1	O15118-1.2	Y423T	Pathogenic	0.718
NPC1	O15118-1.2	Y423V	Pathogenic	0.652
NPC1	O15118-1.2	Y423W	Neutral	0.277
NPC1	O15118-1.2	P424A	Pathogenic	0.587
NPC1	O15118-1.2	P424C	Pathogenic	0.742
NPC1	O15118-1.2	P424D	Neutral	0.466
NPC1	O15118-1.2	P424E	Pathogenic	0.504
NPC1	O15118-1.2	P424F	Pathogenic	0.806
NPC1	O15118-1.2	P424G	Pathogenic	0.68
NPC1	O15118-1.2	P424H	Pathogenic	0.671
NPC1	O15118-1.2	P424I	Pathogenic	0.725
NPC1	O15118-1.2	P424K	Pathogenic	0.514
NPC1	O15118-1.2	P424L	Pathogenic	0.731
NPC1	O15118-1.2	P424M	Pathogenic	0.684
NPC1	O15118-1.2	P424N	Pathogenic	0.583
NPC1	O15118-1.2	P424Q	Pathogenic	0.546
NPC1	O15118-1.2	P424R	Pathogenic	0.626
NPC1	O15118-1.2	P424S	Pathogenic	0.55
NPC1	O15118-1.2	P424T	Pathogenic	0.554
NPC1	O15118-1.2	P424V	Pathogenic	0.66
NPC1	O15118-1.2	P424W	Pathogenic	0.808
NPC1	O15118-1.2	P424Y	Pathogenic	0.794
NPC1	O15118-1.2	S425A	Neutral	0.213
NPC1	O15118-1.2	S425C	Neutral	0.328
NPC1	O15118-1.2	S425D	Neutral	0.273
NPC1	O15118-1.2	S425E	Neutral	0.305
NPC1	O15118-1.2	S425F	Neutral	0.425
NPC1	O15118-1.2	S425G	Neutral	0.331
NPC1	O15118-1.2	S425H	Neutral	0.44
NPC1	O15118-1.2	S425I	Neutral	0.407
NPC1	O15118-1.2	S425K	Neutral	0.313
NPC1	O15118-1.2	S425L	Neutral	0.416
NPC1	O15118-1.2	S425M	Neutral	0.361
NPC1	O15118-1.2	S425N	Neutral	0.218
NPC1	O15118-1.2	S425P	Neutral	0.353
NPC1	O15118-1.2	S425Q	Neutral	0.341
NPC1	O15118-1.2	S425R	Neutral	0.419
NPC1	O15118-1.2	S425T	Neutral	0.23
NPC1	O15118-1.2	S425V	Neutral	0.427
NPC1	O15118-1.2	S425W	Pathogenic	0.524
NPC1	O15118-1.2	S425Y	Pathogenic	0.502
NPC1	O15118-1.2	G426A	Pathogenic	0.853
NPC1	O15118-1.2	G426C	Pathogenic	0.943
NPC1	O15118-1.2	G426D	Pathogenic	0.894
NPC1	O15118-1.2	G426E	Pathogenic	0.936
NPC1	O15118-1.2	G426F	Pathogenic	0.945
NPC1	O15118-1.2	G426H	Pathogenic	0.948
NPC1	O15118-1.2	G426I	Pathogenic	0.959
NPC1	O15118-1.2	G426K	Pathogenic	0.938
NPC1	O15118-1.2	G426L	Pathogenic	0.96
NPC1	O15118-1.2	G426M	Pathogenic	0.95
NPC1	O15118-1.2	G426N	Pathogenic	0.863
NPC1	O15118-1.2	G426P	Pathogenic	0.926
NPC1	O15118-1.2	G426Q	Pathogenic	0.945
NPC1	O15118-1.2	G426R	Pathogenic	0.942
NPC1	O15118-1.2	G426S	Pathogenic	0.868
NPC1	O15118-1.2	G426T	Pathogenic	0.937
NPC1	O15118-1.2	G426V	Pathogenic	0.945
NPC1	O15118-1.2	G426W	Pathogenic	0.922
NPC1	O15118-1.2	G426Y	Pathogenic	0.959
NPC1	O15118-1.2	A427C	Neutral	0.14
NPC1	O15118-1.2	A427D	Neutral	0.241
NPC1	O15118-1.2	A427E	Neutral	0.201
NPC1	O15118-1.2	A427F	Neutral	0.266
NPC1	O15118-1.2	A427G	Neutral	0.155
NPC1	O15118-1.2	A427H	Neutral	0.335
NPC1	O15118-1.2	A427I	Neutral	0.186
NPC1	O15118-1.2	A427K	Neutral	0.207
NPC1	O15118-1.2	A427L	Neutral	0.192
NPC1	O15118-1.2	A427M	Neutral	0.217
NPC1	O15118-1.2	A427N	Neutral	0.257
NPC1	O15118-1.2	A427P	Neutral	0.211
NPC1	O15118-1.2	A427Q	Neutral	0.229
NPC1	O15118-1.2	A427R	Neutral	0.22
NPC1	O15118-1.2	A427S	Neutral	0.102
NPC1	O15118-1.2	A427T	Neutral	0.173
NPC1	O15118-1.2	A427V	Neutral	0.144
NPC1	O15118-1.2	A427W	Neutral	0.351
NPC1	O15118-1.2	A427Y	Neutral	0.331
NPC1	O15118-1.2	D428A	Pathogenic	0.633
NPC1	O15118-1.2	D428C	Pathogenic	0.643
NPC1	O15118-1.2	D428E	Neutral	0.327
NPC1	O15118-1.2	D428F	Pathogenic	0.636
NPC1	O15118-1.2	D428G	Pathogenic	0.593
NPC1	O15118-1.2	D428H	Pathogenic	0.558
NPC1	O15118-1.2	D428I	Pathogenic	0.619
NPC1	O15118-1.2	D428K	Pathogenic	0.637
NPC1	O15118-1.2	D428L	Pathogenic	0.712
NPC1	O15118-1.2	D428M	Pathogenic	0.663
NPC1	O15118-1.2	D428N	Neutral	0.395
NPC1	O15118-1.2	D428P	Neutral	0.471
NPC1	O15118-1.2	D428Q	Neutral	0.485
NPC1	O15118-1.2	D428R	Pathogenic	0.736
NPC1	O15118-1.2	D428S	Neutral	0.463
NPC1	O15118-1.2	D428T	Pathogenic	0.51
NPC1	O15118-1.2	D428V	Pathogenic	0.638
NPC1	O15118-1.2	D428W	Pathogenic	0.723
NPC1	O15118-1.2	D428Y	Pathogenic	0.705
NPC1	O15118-1.2	V429A	Neutral	0.427
NPC1	O15118-1.2	V429C	Pathogenic	0.55
NPC1	O15118-1.2	V429D	Pathogenic	0.589
NPC1	O15118-1.2	V429E	Neutral	0.489
NPC1	O15118-1.2	V429F	Pathogenic	0.539
NPC1	O15118-1.2	V429G	Pathogenic	0.706
NPC1	O15118-1.2	V429H	Pathogenic	0.658
NPC1	O15118-1.2	V429I	Neutral	0.188
NPC1	O15118-1.2	V429K	Neutral	0.499
NPC1	O15118-1.2	V429L	Neutral	0.342
NPC1	O15118-1.2	V429M	Neutral	0.378
NPC1	O15118-1.2	V429N	Pathogenic	0.595
NPC1	O15118-1.2	V429P	Pathogenic	0.616
NPC1	O15118-1.2	V429Q	Pathogenic	0.531
NPC1	O15118-1.2	V429R	Pathogenic	0.612
NPC1	O15118-1.2	V429S	Pathogenic	0.581
NPC1	O15118-1.2	V429T	Neutral	0.385
NPC1	O15118-1.2	V429W	Pathogenic	0.72
NPC1	O15118-1.2	V429Y	Pathogenic	0.573
NPC1	O15118-1.2	P430A	Neutral	0.458
NPC1	O15118-1.2	P430C	Pathogenic	0.631
NPC1	O15118-1.2	P430D	Neutral	0.341
NPC1	O15118-1.2	P430E	Neutral	0.376
NPC1	O15118-1.2	P430F	Pathogenic	0.711
NPC1	O15118-1.2	P430G	Pathogenic	0.557
NPC1	O15118-1.2	P430H	Pathogenic	0.547
NPC1	O15118-1.2	P430I	Pathogenic	0.609
NPC1	O15118-1.2	P430K	Neutral	0.385
NPC1	O15118-1.2	P430L	Pathogenic	0.618
NPC1	O15118-1.2	P430M	Pathogenic	0.562
NPC1	O15118-1.2	P430N	Neutral	0.453
NPC1	O15118-1.2	P430Q	Neutral	0.416
NPC1	O15118-1.2	P430R	Neutral	0.498
NPC1	O15118-1.2	P430S	Neutral	0.421
NPC1	O15118-1.2	P430T	Neutral	0.424
NPC1	O15118-1.2	P430V	Pathogenic	0.535
NPC1	O15118-1.2	P430W	Pathogenic	0.715
NPC1	O15118-1.2	P430Y	Pathogenic	0.696
NPC1	O15118-1.2	F431A	Pathogenic	0.952
NPC1	O15118-1.2	F431C	Pathogenic	0.957
NPC1	O15118-1.2	F431D	Pathogenic	0.947
NPC1	O15118-1.2	F431E	Pathogenic	0.943
NPC1	O15118-1.2	F431G	Pathogenic	0.967
NPC1	O15118-1.2	F431H	Pathogenic	0.904
NPC1	O15118-1.2	F431I	Pathogenic	0.914
NPC1	O15118-1.2	F431K	Pathogenic	0.927
NPC1	O15118-1.2	F431L	Pathogenic	0.912
NPC1	O15118-1.2	F431M	Pathogenic	0.899
NPC1	O15118-1.2	F431N	Pathogenic	0.948
NPC1	O15118-1.2	F431P	Pathogenic	0.977
NPC1	O15118-1.2	F431Q	Pathogenic	0.949
NPC1	O15118-1.2	F431R	Pathogenic	0.931
NPC1	O15118-1.2	F431S	Pathogenic	0.945
NPC1	O15118-1.2	F431T	Pathogenic	0.944
NPC1	O15118-1.2	F431V	Pathogenic	0.936
NPC1	O15118-1.2	F431W	Pathogenic	0.873
NPC1	O15118-1.2	F431Y	Pathogenic	0.712
NPC1	O15118-1.2	G432A	Pathogenic	0.875
NPC1	O15118-1.2	G432C	Pathogenic	0.952
NPC1	O15118-1.2	G432D	Pathogenic	0.911
NPC1	O15118-1.2	G432E	Pathogenic	0.946
NPC1	O15118-1.2	G432F	Pathogenic	0.953
NPC1	O15118-1.2	G432H	Pathogenic	0.956
NPC1	O15118-1.2	G432I	Pathogenic	0.966
NPC1	O15118-1.2	G432K	Pathogenic	0.948
NPC1	O15118-1.2	G432L	Pathogenic	0.967
NPC1	O15118-1.2	G432M	Pathogenic	0.958
NPC1	O15118-1.2	G432N	Pathogenic	0.883
NPC1	O15118-1.2	G432P	Pathogenic	0.938
NPC1	O15118-1.2	G432Q	Pathogenic	0.954
NPC1	O15118-1.2	G432R	Pathogenic	0.951
NPC1	O15118-1.2	G432S	Pathogenic	0.888
NPC1	O15118-1.2	G432T	Pathogenic	0.947
NPC1	O15118-1.2	G432V	Pathogenic	0.954
NPC1	O15118-1.2	G432W	Pathogenic	0.934
NPC1	O15118-1.2	G432Y	Pathogenic	0.966
NPC1	O15118-1.2	P433A	Pathogenic	0.88
NPC1	O15118-1.2	P433C	Pathogenic	0.937
NPC1	O15118-1.2	P433D	Pathogenic	0.818
NPC1	O15118-1.2	P433E	Pathogenic	0.84
NPC1	O15118-1.2	P433F	Pathogenic	0.956
NPC1	O15118-1.2	P433G	Pathogenic	0.916
NPC1	O15118-1.2	P433H	Pathogenic	0.913
NPC1	O15118-1.2	P433I	Pathogenic	0.932
NPC1	O15118-1.2	P433K	Pathogenic	0.845
NPC1	O15118-1.2	P433L	Pathogenic	0.934
NPC1	O15118-1.2	P433M	Pathogenic	0.918
NPC1	O15118-1.2	P433N	Pathogenic	0.878
NPC1	O15118-1.2	P433Q	Pathogenic	0.861
NPC1	O15118-1.2	P433R	Pathogenic	0.896
NPC1	O15118-1.2	P433S	Pathogenic	0.864
NPC1	O15118-1.2	P433T	Pathogenic	0.865
NPC1	O15118-1.2	P433V	Pathogenic	0.909
NPC1	O15118-1.2	P433W	Pathogenic	0.956
NPC1	O15118-1.2	P433Y	Pathogenic	0.952
NPC1	O15118-1.2	P434A	Pathogenic	0.666
NPC1	O15118-1.2	P434C	Pathogenic	0.802
NPC1	O15118-1.2	P434D	Pathogenic	0.55
NPC1	O15118-1.2	P434E	Pathogenic	0.588
NPC1	O15118-1.2	P434F	Pathogenic	0.854
NPC1	O15118-1.2	P434G	Pathogenic	0.749
NPC1	O15118-1.2	P434H	Pathogenic	0.741
NPC1	O15118-1.2	P434I	Pathogenic	0.787
NPC1	O15118-1.2	P434K	Pathogenic	0.597
NPC1	O15118-1.2	P434L	Pathogenic	0.793
NPC1	O15118-1.2	P434M	Pathogenic	0.752
NPC1	O15118-1.2	P434N	Pathogenic	0.662
NPC1	O15118-1.2	P434Q	Pathogenic	0.628
NPC1	O15118-1.2	P434R	Pathogenic	0.701
NPC1	O15118-1.2	P434S	Pathogenic	0.632
NPC1	O15118-1.2	P434T	Pathogenic	0.635
NPC1	O15118-1.2	P434V	Pathogenic	0.731
NPC1	O15118-1.2	P434W	Pathogenic	0.856
NPC1	O15118-1.2	P434Y	Pathogenic	0.844
NPC1	O15118-1.2	L435A	Pathogenic	0.745
NPC1	O15118-1.2	L435C	Pathogenic	0.765
NPC1	O15118-1.2	L435D	Pathogenic	0.849
NPC1	O15118-1.2	L435E	Pathogenic	0.782
NPC1	O15118-1.2	L435F	Pathogenic	0.699
NPC1	O15118-1.2	L435G	Pathogenic	0.904
NPC1	O15118-1.2	L435H	Pathogenic	0.814
NPC1	O15118-1.2	L435I	Neutral	0.5
NPC1	O15118-1.2	L435K	Pathogenic	0.679
NPC1	O15118-1.2	L435M	Neutral	0.469
NPC1	O15118-1.2	L435N	Pathogenic	0.797
NPC1	O15118-1.2	L435P	Pathogenic	0.863
NPC1	O15118-1.2	L435Q	Pathogenic	0.731
NPC1	O15118-1.2	L435R	Pathogenic	0.695
NPC1	O15118-1.2	L435S	Pathogenic	0.787
NPC1	O15118-1.2	L435T	Pathogenic	0.711
NPC1	O15118-1.2	L435V	Pathogenic	0.592
NPC1	O15118-1.2	L435W	Pathogenic	0.836
NPC1	O15118-1.2	L435Y	Pathogenic	0.74
NPC1	O15118-1.2	D436A	Neutral	0.402
NPC1	O15118-1.2	D436C	Neutral	0.413
NPC1	O15118-1.2	D436E	Neutral	0.16
NPC1	O15118-1.2	D436F	Neutral	0.406
NPC1	O15118-1.2	D436G	Neutral	0.362
NPC1	O15118-1.2	D436H	Neutral	0.331
NPC1	O15118-1.2	D436I	Neutral	0.389
NPC1	O15118-1.2	D436K	Neutral	0.407
NPC1	O15118-1.2	D436L	Neutral	0.492
NPC1	O15118-1.2	D436M	Neutral	0.435
NPC1	O15118-1.2	D436N	Neutral	0.203
NPC1	O15118-1.2	D436P	Neutral	0.258
NPC1	O15118-1.2	D436Q	Neutral	0.269
NPC1	O15118-1.2	D436R	Pathogenic	0.521
NPC1	O15118-1.2	D436S	Neutral	0.252
NPC1	O15118-1.2	D436T	Neutral	0.289
NPC1	O15118-1.2	D436V	Neutral	0.408
NPC1	O15118-1.2	D436W	Pathogenic	0.505
NPC1	O15118-1.2	D436Y	Neutral	0.482
NPC1	O15118-1.2	I437A	Neutral	0.287
NPC1	O15118-1.2	I437C	Neutral	0.31
NPC1	O15118-1.2	I437D	Neutral	0.345
NPC1	O15118-1.2	I437E	Neutral	0.331
NPC1	O15118-1.2	I437F	Neutral	0.254
NPC1	O15118-1.2	I437G	Pathogenic	0.565
NPC1	O15118-1.2	I437H	Neutral	0.377
NPC1	O15118-1.2	I437K	Neutral	0.3
NPC1	O15118-1.2	I437L	Neutral	0.125
NPC1	O15118-1.2	I437M	Neutral	0.152
NPC1	O15118-1.2	I437N	Neutral	0.351
NPC1	O15118-1.2	I437P	Neutral	0.465
NPC1	O15118-1.2	I437Q	Neutral	0.355
NPC1	O15118-1.2	I437R	Neutral	0.316
NPC1	O15118-1.2	I437S	Neutral	0.338
NPC1	O15118-1.2	I437T	Neutral	0.253
NPC1	O15118-1.2	I437V	Neutral	0.085
NPC1	O15118-1.2	I437W	Pathogenic	0.526
NPC1	O15118-1.2	I437Y	Neutral	0.282
NPC1	O15118-1.2	Q438A	Neutral	0.32
NPC1	O15118-1.2	Q438C	Neutral	0.421
NPC1	O15118-1.2	Q438D	Neutral	0.216
NPC1	O15118-1.2	Q438E	Neutral	0.106
NPC1	O15118-1.2	Q438F	Neutral	0.348
NPC1	O15118-1.2	Q438G	Neutral	0.463
NPC1	O15118-1.2	Q438H	Neutral	0.208
NPC1	O15118-1.2	Q438I	Neutral	0.332
NPC1	O15118-1.2	Q438K	Neutral	0.147
NPC1	O15118-1.2	Q438L	Neutral	0.259
NPC1	O15118-1.2	Q438M	Neutral	0.159
NPC1	O15118-1.2	Q438N	Neutral	0.22
NPC1	O15118-1.2	Q438P	Neutral	0.264
NPC1	O15118-1.2	Q438R	Neutral	0.156
NPC1	O15118-1.2	Q438S	Neutral	0.257
NPC1	O15118-1.2	Q438T	Neutral	0.291
NPC1	O15118-1.2	Q438V	Neutral	0.289
NPC1	O15118-1.2	Q438W	Neutral	0.269
NPC1	O15118-1.2	Q438Y	Neutral	0.252
NPC1	O15118-1.2	I439A	Pathogenic	0.669
NPC1	O15118-1.2	I439C	Pathogenic	0.693
NPC1	O15118-1.2	I439D	Pathogenic	0.726
NPC1	O15118-1.2	I439E	Pathogenic	0.713
NPC1	O15118-1.2	I439F	Pathogenic	0.63
NPC1	O15118-1.2	I439G	Pathogenic	0.867
NPC1	O15118-1.2	I439H	Pathogenic	0.752
NPC1	O15118-1.2	I439K	Pathogenic	0.683
NPC1	O15118-1.2	I439L	Neutral	0.417
NPC1	O15118-1.2	I439M	Neutral	0.474
NPC1	O15118-1.2	I439N	Pathogenic	0.731
NPC1	O15118-1.2	I439P	Pathogenic	0.814
NPC1	O15118-1.2	I439Q	Pathogenic	0.734
NPC1	O15118-1.2	I439R	Pathogenic	0.699
NPC1	O15118-1.2	I439S	Pathogenic	0.719
NPC1	O15118-1.2	I439T	Pathogenic	0.63
NPC1	O15118-1.2	I439V	Neutral	0.317
NPC1	O15118-1.2	I439W	Pathogenic	0.848
NPC1	O15118-1.2	I439Y	Pathogenic	0.664
NPC1	O15118-1.2	L440A	Pathogenic	0.911
NPC1	O15118-1.2	L440C	Pathogenic	0.919
NPC1	O15118-1.2	L440D	Pathogenic	0.951
NPC1	O15118-1.2	L440E	Pathogenic	0.926
NPC1	O15118-1.2	L440F	Pathogenic	0.89
NPC1	O15118-1.2	L440G	Pathogenic	0.97
NPC1	O15118-1.2	L440H	Pathogenic	0.938
NPC1	O15118-1.2	L440I	Pathogenic	0.777
NPC1	O15118-1.2	L440K	Pathogenic	0.88
NPC1	O15118-1.2	L440M	Pathogenic	0.755
NPC1	O15118-1.2	L440N	Pathogenic	0.932
NPC1	O15118-1.2	L440P	Pathogenic	0.956
NPC1	O15118-1.2	L440Q	Pathogenic	0.904
NPC1	O15118-1.2	L440R	Pathogenic	0.888
NPC1	O15118-1.2	L440S	Pathogenic	0.928
NPC1	O15118-1.2	L440T	Pathogenic	0.895
NPC1	O15118-1.2	L440V	Pathogenic	0.835
NPC1	O15118-1.2	L440W	Pathogenic	0.947
NPC1	O15118-1.2	L440Y	Pathogenic	0.908
NPC1	O15118-1.2	H441A	Pathogenic	0.773
NPC1	O15118-1.2	H441C	Pathogenic	0.781
NPC1	O15118-1.2	H441D	Pathogenic	0.612
NPC1	O15118-1.2	H441E	Pathogenic	0.501
NPC1	O15118-1.2	H441F	Pathogenic	0.536
NPC1	O15118-1.2	H441G	Pathogenic	0.795
NPC1	O15118-1.2	H441I	Pathogenic	0.699
NPC1	O15118-1.2	H441K	Pathogenic	0.58
NPC1	O15118-1.2	H441L	Pathogenic	0.706
NPC1	O15118-1.2	H441M	Pathogenic	0.657
NPC1	O15118-1.2	H441N	Neutral	0.428
NPC1	O15118-1.2	H441P	Pathogenic	0.721
NPC1	O15118-1.2	H441Q	Pathogenic	0.528
NPC1	O15118-1.2	H441R	Pathogenic	0.502
NPC1	O15118-1.2	H441S	Pathogenic	0.692
NPC1	O15118-1.2	H441T	Pathogenic	0.748
NPC1	O15118-1.2	H441V	Pathogenic	0.747
NPC1	O15118-1.2	H441W	Pathogenic	0.633
NPC1	O15118-1.2	H441Y	Neutral	0.331
NPC1	O15118-1.2	Q442A	Pathogenic	0.762
NPC1	O15118-1.2	Q442C	Pathogenic	0.831
NPC1	O15118-1.2	Q442D	Pathogenic	0.651
NPC1	O15118-1.2	Q442E	Neutral	0.447
NPC1	O15118-1.2	Q442F	Pathogenic	0.783
NPC1	O15118-1.2	Q442G	Pathogenic	0.854
NPC1	O15118-1.2	Q442H	Pathogenic	0.64
NPC1	O15118-1.2	Q442I	Pathogenic	0.771
NPC1	O15118-1.2	Q442K	Pathogenic	0.538
NPC1	O15118-1.2	Q442L	Pathogenic	0.703
NPC1	O15118-1.2	Q442M	Pathogenic	0.561
NPC1	O15118-1.2	Q442N	Pathogenic	0.657
NPC1	O15118-1.2	Q442P	Pathogenic	0.708
NPC1	O15118-1.2	Q442R	Pathogenic	0.557
NPC1	O15118-1.2	Q442S	Pathogenic	0.702
NPC1	O15118-1.2	Q442T	Pathogenic	0.736
NPC1	O15118-1.2	Q442V	Pathogenic	0.734
NPC1	O15118-1.2	Q442W	Pathogenic	0.714
NPC1	O15118-1.2	Q442Y	Pathogenic	0.695
NPC1	O15118-1.2	V443A	Pathogenic	0.747
NPC1	O15118-1.2	V443C	Pathogenic	0.829
NPC1	O15118-1.2	V443D	Pathogenic	0.85
NPC1	O15118-1.2	V443E	Pathogenic	0.791
NPC1	O15118-1.2	V443F	Pathogenic	0.822
NPC1	O15118-1.2	V443G	Pathogenic	0.905
NPC1	O15118-1.2	V443H	Pathogenic	0.884
NPC1	O15118-1.2	V443I	Neutral	0.479
NPC1	O15118-1.2	V443K	Pathogenic	0.798
NPC1	O15118-1.2	V443L	Pathogenic	0.673
NPC1	O15118-1.2	V443M	Pathogenic	0.707
NPC1	O15118-1.2	V443N	Pathogenic	0.853
NPC1	O15118-1.2	V443P	Pathogenic	0.864
NPC1	O15118-1.2	V443Q	Pathogenic	0.818
NPC1	O15118-1.2	V443R	Pathogenic	0.862
NPC1	O15118-1.2	V443S	Pathogenic	0.846
NPC1	O15118-1.2	V443T	Pathogenic	0.713
NPC1	O15118-1.2	V443W	Pathogenic	0.91
NPC1	O15118-1.2	V443Y	Pathogenic	0.842
NPC1	O15118-1.2	L444A	Pathogenic	0.846
NPC1	O15118-1.2	L444C	Pathogenic	0.86
NPC1	O15118-1.2	L444D	Pathogenic	0.914
NPC1	O15118-1.2	L444E	Pathogenic	0.871
NPC1	O15118-1.2	L444F	Pathogenic	0.814
NPC1	O15118-1.2	L444G	Pathogenic	0.947
NPC1	O15118-1.2	L444H	Pathogenic	0.892
NPC1	O15118-1.2	L444I	Pathogenic	0.653
NPC1	O15118-1.2	L444K	Pathogenic	0.799
NPC1	O15118-1.2	L444M	Pathogenic	0.625
NPC1	O15118-1.2	L444N	Pathogenic	0.881
NPC1	O15118-1.2	L444P	Pathogenic	0.922
NPC1	O15118-1.2	L444Q	Pathogenic	0.836
NPC1	O15118-1.2	L444R	Pathogenic	0.811
NPC1	O15118-1.2	L444S	Pathogenic	0.874
NPC1	O15118-1.2	L444T	Pathogenic	0.822
NPC1	O15118-1.2	L444V	Pathogenic	0.732
NPC1	O15118-1.2	L444W	Pathogenic	0.906
NPC1	O15118-1.2	L444Y	Pathogenic	0.843
NPC1	O15118-1.2	D445A	Pathogenic	0.705
NPC1	O15118-1.2	D445C	Pathogenic	0.715
NPC1	O15118-1.2	D445E	Neutral	0.403
NPC1	O15118-1.2	D445F	Pathogenic	0.708
NPC1	O15118-1.2	D445G	Pathogenic	0.669
NPC1	O15118-1.2	D445H	Pathogenic	0.637
NPC1	O15118-1.2	D445I	Pathogenic	0.693
NPC1	O15118-1.2	D445K	Pathogenic	0.709
NPC1	O15118-1.2	D445L	Pathogenic	0.775
NPC1	O15118-1.2	D445M	Pathogenic	0.732
NPC1	O15118-1.2	D445N	Neutral	0.475
NPC1	O15118-1.2	D445P	Pathogenic	0.552
NPC1	O15118-1.2	D445Q	Pathogenic	0.567
NPC1	O15118-1.2	D445R	Pathogenic	0.794
NPC1	O15118-1.2	D445S	Pathogenic	0.545
NPC1	O15118-1.2	D445T	Pathogenic	0.592
NPC1	O15118-1.2	D445V	Pathogenic	0.71
NPC1	O15118-1.2	D445W	Pathogenic	0.784
NPC1	O15118-1.2	D445Y	Pathogenic	0.768
NPC1	O15118-1.2	L446A	Pathogenic	0.944
NPC1	O15118-1.2	L446C	Pathogenic	0.95
NPC1	O15118-1.2	L446D	Pathogenic	0.97
NPC1	O15118-1.2	L446E	Pathogenic	0.954
NPC1	O15118-1.2	L446F	Pathogenic	0.931
NPC1	O15118-1.2	L446G	Pathogenic	0.982
NPC1	O15118-1.2	L446H	Pathogenic	0.962
NPC1	O15118-1.2	L446I	Pathogenic	0.853
NPC1	O15118-1.2	L446K	Pathogenic	0.925
NPC1	O15118-1.2	L446M	Pathogenic	0.837
NPC1	O15118-1.2	L446N	Pathogenic	0.958
NPC1	O15118-1.2	L446P	Pathogenic	0.973
NPC1	O15118-1.2	L446Q	Pathogenic	0.94
NPC1	O15118-1.2	L446R	Pathogenic	0.93
NPC1	O15118-1.2	L446S	Pathogenic	0.955
NPC1	O15118-1.2	L446T	Pathogenic	0.934
NPC1	O15118-1.2	L446V	Pathogenic	0.894
NPC1	O15118-1.2	L446W	Pathogenic	0.967
NPC1	O15118-1.2	L446Y	Pathogenic	0.943
NPC1	O15118-1.2	Q447A	Pathogenic	0.969
NPC1	O15118-1.2	Q447C	Pathogenic	0.98
NPC1	O15118-1.2	Q447D	Pathogenic	0.948
NPC1	O15118-1.2	Q447E	Pathogenic	0.887
NPC1	O15118-1.2	Q447F	Pathogenic	0.972
NPC1	O15118-1.2	Q447G	Pathogenic	0.983
NPC1	O15118-1.2	Q447H	Pathogenic	0.945
NPC1	O15118-1.2	Q447I	Pathogenic	0.97
NPC1	O15118-1.2	Q447K	Pathogenic	0.919
NPC1	O15118-1.2	Q447L	Pathogenic	0.958
NPC1	O15118-1.2	Q447M	Pathogenic	0.926
NPC1	O15118-1.2	Q447N	Pathogenic	0.949
NPC1	O15118-1.2	Q447P	Pathogenic	0.959
NPC1	O15118-1.2	Q447R	Pathogenic	0.924
NPC1	O15118-1.2	Q447S	Pathogenic	0.958
NPC1	O15118-1.2	Q447T	Pathogenic	0.964
NPC1	O15118-1.2	Q447V	Pathogenic	0.964
NPC1	O15118-1.2	Q447W	Pathogenic	0.96
NPC1	O15118-1.2	Q447Y	Pathogenic	0.957
NPC1	O15118-1.2	I448A	Neutral	0.217
NPC1	O15118-1.2	I448C	Neutral	0.236
NPC1	O15118-1.2	I448D	Neutral	0.265
NPC1	O15118-1.2	I448E	Neutral	0.253
NPC1	O15118-1.2	I448F	Neutral	0.189
NPC1	O15118-1.2	I448G	Neutral	0.471
NPC1	O15118-1.2	I448H	Neutral	0.293
NPC1	O15118-1.2	I448K	Neutral	0.227
NPC1	O15118-1.2	I448L	Neutral	0.089
NPC1	O15118-1.2	I448M	Neutral	0.11
NPC1	O15118-1.2	I448N	Neutral	0.271
NPC1	O15118-1.2	I448P	Neutral	0.374
NPC1	O15118-1.2	I448Q	Neutral	0.274
NPC1	O15118-1.2	I448R	Neutral	0.24
NPC1	O15118-1.2	I448S	Neutral	0.259
NPC1	O15118-1.2	I448T	Neutral	0.188
NPC1	O15118-1.2	I448V	Neutral	0.06
NPC1	O15118-1.2	I448W	Neutral	0.432
NPC1	O15118-1.2	I448Y	Neutral	0.212
NPC1	O15118-1.2	A449C	Neutral	0.265
NPC1	O15118-1.2	A449D	Neutral	0.413
NPC1	O15118-1.2	A449E	Neutral	0.358
NPC1	O15118-1.2	A449F	Neutral	0.445
NPC1	O15118-1.2	A449G	Neutral	0.29
NPC1	O15118-1.2	A449H	Pathogenic	0.528
NPC1	O15118-1.2	A449I	Neutral	0.337
NPC1	O15118-1.2	A449K	Neutral	0.367
NPC1	O15118-1.2	A449L	Neutral	0.345
NPC1	O15118-1.2	A449M	Neutral	0.381
NPC1	O15118-1.2	A449N	Neutral	0.434
NPC1	O15118-1.2	A449P	Neutral	0.372
NPC1	O15118-1.2	A449Q	Neutral	0.398
NPC1	O15118-1.2	A449R	Neutral	0.385
NPC1	O15118-1.2	A449S	Neutral	0.202
NPC1	O15118-1.2	A449T	Neutral	0.317
NPC1	O15118-1.2	A449V	Neutral	0.272
NPC1	O15118-1.2	A449W	Pathogenic	0.545
NPC1	O15118-1.2	A449Y	Pathogenic	0.523
NPC1	O15118-1.2	I450A	Pathogenic	0.895
NPC1	O15118-1.2	I450C	Pathogenic	0.905
NPC1	O15118-1.2	I450D	Pathogenic	0.918
NPC1	O15118-1.2	I450E	Pathogenic	0.913
NPC1	O15118-1.2	I450F	Pathogenic	0.878
NPC1	O15118-1.2	I450G	Pathogenic	0.965
NPC1	O15118-1.2	I450H	Pathogenic	0.928
NPC1	O15118-1.2	I450K	Pathogenic	0.901
NPC1	O15118-1.2	I450L	Pathogenic	0.752
NPC1	O15118-1.2	I450M	Pathogenic	0.792
NPC1	O15118-1.2	I450N	Pathogenic	0.92
NPC1	O15118-1.2	I450P	Pathogenic	0.949
NPC1	O15118-1.2	I450Q	Pathogenic	0.921
NPC1	O15118-1.2	I450R	Pathogenic	0.907
NPC1	O15118-1.2	I450S	Pathogenic	0.915
NPC1	O15118-1.2	I450T	Pathogenic	0.878
NPC1	O15118-1.2	I450V	Pathogenic	0.663
NPC1	O15118-1.2	I450W	Pathogenic	0.959
NPC1	O15118-1.2	I450Y	Pathogenic	0.893
NPC1	O15118-1.2	E451A	Pathogenic	0.538
NPC1	O15118-1.2	E451C	Pathogenic	0.726
NPC1	O15118-1.2	E451D	Neutral	0.293
NPC1	O15118-1.2	E451F	Pathogenic	0.583
NPC1	O15118-1.2	E451G	Pathogenic	0.681
NPC1	O15118-1.2	E451H	Neutral	0.408
NPC1	O15118-1.2	E451I	Pathogenic	0.566
NPC1	O15118-1.2	E451K	Neutral	0.373
NPC1	O15118-1.2	E451L	Pathogenic	0.574
NPC1	O15118-1.2	E451M	Pathogenic	0.517
NPC1	O15118-1.2	E451N	Neutral	0.474
NPC1	O15118-1.2	E451P	Neutral	0.47
NPC1	O15118-1.2	E451Q	Neutral	0.259
NPC1	O15118-1.2	E451R	Neutral	0.486
NPC1	O15118-1.2	E451S	Neutral	0.462
NPC1	O15118-1.2	E451T	Pathogenic	0.503
NPC1	O15118-1.2	E451V	Pathogenic	0.502
NPC1	O15118-1.2	E451W	Pathogenic	0.587
NPC1	O15118-1.2	E451Y	Pathogenic	0.565
NPC1	O15118-1.2	N452A	Neutral	0.196
NPC1	O15118-1.2	N452C	Neutral	0.204
NPC1	O15118-1.2	N452D	Neutral	0.078
NPC1	O15118-1.2	N452E	Neutral	0.12
NPC1	O15118-1.2	N452F	Neutral	0.189
NPC1	O15118-1.2	N452G	Neutral	0.123
NPC1	O15118-1.2	N452H	Neutral	0.072
NPC1	O15118-1.2	N452I	Neutral	0.178
NPC1	O15118-1.2	N452K	Neutral	0.125
NPC1	O15118-1.2	N452L	Neutral	0.183
NPC1	O15118-1.2	N452M	Neutral	0.151
NPC1	O15118-1.2	N452P	Neutral	0.156
NPC1	O15118-1.2	N452Q	Neutral	0.112
NPC1	O15118-1.2	N452R	Neutral	0.133
NPC1	O15118-1.2	N452S	Neutral	0.077
NPC1	O15118-1.2	N452T	Neutral	0.089
NPC1	O15118-1.2	N452V	Neutral	0.19
NPC1	O15118-1.2	N452W	Neutral	0.258
NPC1	O15118-1.2	N452Y	Neutral	0.178
NPC1	O15118-1.2	I453A	Pathogenic	0.811
NPC1	O15118-1.2	I453C	Pathogenic	0.827
NPC1	O15118-1.2	I453D	Pathogenic	0.849
NPC1	O15118-1.2	I453E	Pathogenic	0.84
NPC1	O15118-1.2	I453F	Pathogenic	0.783
NPC1	O15118-1.2	I453G	Pathogenic	0.933
NPC1	O15118-1.2	I453H	Pathogenic	0.866
NPC1	O15118-1.2	I453K	Pathogenic	0.821
NPC1	O15118-1.2	I453L	Pathogenic	0.603
NPC1	O15118-1.2	I453M	Pathogenic	0.657
NPC1	O15118-1.2	I453N	Pathogenic	0.852
NPC1	O15118-1.2	I453P	Pathogenic	0.903
NPC1	O15118-1.2	I453Q	Pathogenic	0.854
NPC1	O15118-1.2	I453R	Pathogenic	0.831
NPC1	O15118-1.2	I453S	Pathogenic	0.845
NPC1	O15118-1.2	I453T	Pathogenic	0.783
NPC1	O15118-1.2	I453V	Neutral	0.497
NPC1	O15118-1.2	I453W	Pathogenic	0.922
NPC1	O15118-1.2	I453Y	Pathogenic	0.807
NPC1	O15118-1.2	T454A	Neutral	0.368
NPC1	O15118-1.2	T454C	Neutral	0.379
NPC1	O15118-1.2	T454D	Neutral	0.349
NPC1	O15118-1.2	T454E	Neutral	0.379
NPC1	O15118-1.2	T454F	Neutral	0.459
NPC1	O15118-1.2	T454G	Pathogenic	0.569
NPC1	O15118-1.2	T454H	Pathogenic	0.55
NPC1	O15118-1.2	T454I	Neutral	0.35
NPC1	O15118-1.2	T454K	Neutral	0.389
NPC1	O15118-1.2	T454L	Neutral	0.358
NPC1	O15118-1.2	T454M	Neutral	0.394
NPC1	O15118-1.2	T454N	Neutral	0.28
NPC1	O15118-1.2	T454P	Neutral	0.394
NPC1	O15118-1.2	T454Q	Neutral	0.42
NPC1	O15118-1.2	T454R	Neutral	0.406
NPC1	O15118-1.2	T454S	Neutral	0.261
NPC1	O15118-1.2	T454V	Neutral	0.284
NPC1	O15118-1.2	T454W	Neutral	0.463
NPC1	O15118-1.2	T454Y	Pathogenic	0.537
NPC1	O15118-1.2	A455C	Neutral	0.483
NPC1	O15118-1.2	A455D	Pathogenic	0.646
NPC1	O15118-1.2	A455E	Pathogenic	0.591
NPC1	O15118-1.2	A455F	Pathogenic	0.676
NPC1	O15118-1.2	A455G	Pathogenic	0.514
NPC1	O15118-1.2	A455H	Pathogenic	0.744
NPC1	O15118-1.2	A455I	Pathogenic	0.569
NPC1	O15118-1.2	A455K	Pathogenic	0.601
NPC1	O15118-1.2	A455L	Pathogenic	0.577
NPC1	O15118-1.2	A455M	Pathogenic	0.615
NPC1	O15118-1.2	A455N	Pathogenic	0.665
NPC1	O15118-1.2	A455P	Pathogenic	0.606
NPC1	O15118-1.2	A455Q	Pathogenic	0.631
NPC1	O15118-1.2	A455R	Pathogenic	0.618
NPC1	O15118-1.2	A455S	Neutral	0.396
NPC1	O15118-1.2	A455T	Pathogenic	0.546
NPC1	O15118-1.2	A455V	Neutral	0.493
NPC1	O15118-1.2	A455W	Pathogenic	0.757
NPC1	O15118-1.2	A455Y	Pathogenic	0.74
NPC1	O15118-1.2	S456A	Neutral	0.118
NPC1	O15118-1.2	S456C	Neutral	0.195
NPC1	O15118-1.2	S456D	Neutral	0.157
NPC1	O15118-1.2	S456E	Neutral	0.178
NPC1	O15118-1.2	S456F	Neutral	0.268
NPC1	O15118-1.2	S456G	Neutral	0.197
NPC1	O15118-1.2	S456H	Neutral	0.28
NPC1	O15118-1.2	S456I	Neutral	0.254
NPC1	O15118-1.2	S456K	Neutral	0.184
NPC1	O15118-1.2	S456L	Neutral	0.261
NPC1	O15118-1.2	S456M	Neutral	0.219
NPC1	O15118-1.2	S456N	Neutral	0.121
NPC1	O15118-1.2	S456P	Neutral	0.213
NPC1	O15118-1.2	S456Q	Neutral	0.205
NPC1	O15118-1.2	S456R	Neutral	0.264
NPC1	O15118-1.2	S456T	Neutral	0.129
NPC1	O15118-1.2	S456V	Neutral	0.27
NPC1	O15118-1.2	S456W	Neutral	0.353
NPC1	O15118-1.2	S456Y	Neutral	0.333
NPC1	O15118-1.2	Y457A	Pathogenic	0.591
NPC1	O15118-1.2	Y457C	Pathogenic	0.613
NPC1	O15118-1.2	Y457D	Pathogenic	0.562
NPC1	O15118-1.2	Y457E	Neutral	0.45
NPC1	O15118-1.2	Y457F	Neutral	0.116
NPC1	O15118-1.2	Y457G	Pathogenic	0.682
NPC1	O15118-1.2	Y457H	Neutral	0.176
NPC1	O15118-1.2	Y457I	Neutral	0.395
NPC1	O15118-1.2	Y457K	Neutral	0.383
NPC1	O15118-1.2	Y457L	Neutral	0.403
NPC1	O15118-1.2	Y457M	Neutral	0.441
NPC1	O15118-1.2	Y457N	Neutral	0.472
NPC1	O15118-1.2	Y457P	Pathogenic	0.679
NPC1	O15118-1.2	Y457Q	Neutral	0.382
NPC1	O15118-1.2	Y457R	Neutral	0.383
NPC1	O15118-1.2	Y457S	Pathogenic	0.554
NPC1	O15118-1.2	Y457T	Pathogenic	0.548
NPC1	O15118-1.2	Y457V	Neutral	0.471
NPC1	O15118-1.2	Y457W	Neutral	0.154
NPC1	O15118-1.2	D458A	Neutral	0.336
NPC1	O15118-1.2	D458C	Neutral	0.346
NPC1	O15118-1.2	D458E	Neutral	0.125
NPC1	O15118-1.2	D458F	Neutral	0.339
NPC1	O15118-1.2	D458G	Neutral	0.299
NPC1	O15118-1.2	D458H	Neutral	0.27
NPC1	O15118-1.2	D458I	Neutral	0.323
NPC1	O15118-1.2	D458K	Neutral	0.34
NPC1	O15118-1.2	D458L	Neutral	0.421
NPC1	O15118-1.2	D458M	Neutral	0.366
NPC1	O15118-1.2	D458N	Neutral	0.161
NPC1	O15118-1.2	D458P	Neutral	0.207
NPC1	O15118-1.2	D458Q	Neutral	0.217
NPC1	O15118-1.2	D458R	Neutral	0.449
NPC1	O15118-1.2	D458S	Neutral	0.202
NPC1	O15118-1.2	D458T	Neutral	0.234
NPC1	O15118-1.2	D458V	Neutral	0.341
NPC1	O15118-1.2	D458W	Neutral	0.434
NPC1	O15118-1.2	D458Y	Neutral	0.412
NPC1	O15118-1.2	N459A	Pathogenic	0.519
NPC1	O15118-1.2	N459C	Pathogenic	0.531
NPC1	O15118-1.2	N459D	Neutral	0.273
NPC1	O15118-1.2	N459E	Neutral	0.377
NPC1	O15118-1.2	N459F	Pathogenic	0.507
NPC1	O15118-1.2	N459G	Neutral	0.383
NPC1	O15118-1.2	N459H	Neutral	0.256
NPC1	O15118-1.2	N459I	Neutral	0.49
NPC1	O15118-1.2	N459K	Neutral	0.386
NPC1	O15118-1.2	N459L	Neutral	0.498
NPC1	O15118-1.2	N459M	Neutral	0.441
NPC1	O15118-1.2	N459P	Neutral	0.45
NPC1	O15118-1.2	N459Q	Neutral	0.357
NPC1	O15118-1.2	N459R	Neutral	0.404
NPC1	O15118-1.2	N459S	Neutral	0.268
NPC1	O15118-1.2	N459T	Neutral	0.302
NPC1	O15118-1.2	N459V	Pathogenic	0.51
NPC1	O15118-1.2	N459W	Pathogenic	0.606
NPC1	O15118-1.2	N459Y	Neutral	0.489
NPC1	O15118-1.2	E460A	Neutral	0.485
NPC1	O15118-1.2	E460C	Pathogenic	0.681
NPC1	O15118-1.2	E460D	Neutral	0.252
NPC1	O15118-1.2	E460F	Pathogenic	0.531
NPC1	O15118-1.2	E460G	Pathogenic	0.633
NPC1	O15118-1.2	E460H	Neutral	0.358
NPC1	O15118-1.2	E460I	Pathogenic	0.513
NPC1	O15118-1.2	E460K	Neutral	0.325
NPC1	O15118-1.2	E460L	Pathogenic	0.522
NPC1	O15118-1.2	E460M	Neutral	0.464
NPC1	O15118-1.2	E460N	Neutral	0.421
NPC1	O15118-1.2	E460P	Neutral	0.417
NPC1	O15118-1.2	E460Q	Neutral	0.22
NPC1	O15118-1.2	E460R	Neutral	0.433
NPC1	O15118-1.2	E460S	Neutral	0.41
NPC1	O15118-1.2	E460T	Neutral	0.451
NPC1	O15118-1.2	E460V	Neutral	0.449
NPC1	O15118-1.2	E460W	Pathogenic	0.535
NPC1	O15118-1.2	E460Y	Pathogenic	0.513
NPC1	O15118-1.2	T461A	Pathogenic	0.554
NPC1	O15118-1.2	T461C	Pathogenic	0.565
NPC1	O15118-1.2	T461D	Pathogenic	0.533
NPC1	O15118-1.2	T461E	Pathogenic	0.565
NPC1	O15118-1.2	T461F	Pathogenic	0.644
NPC1	O15118-1.2	T461G	Pathogenic	0.738
NPC1	O15118-1.2	T461H	Pathogenic	0.723
NPC1	O15118-1.2	T461I	Pathogenic	0.534
NPC1	O15118-1.2	T461K	Pathogenic	0.575
NPC1	O15118-1.2	T461L	Pathogenic	0.542
NPC1	O15118-1.2	T461M	Pathogenic	0.581
NPC1	O15118-1.2	T461N	Neutral	0.453
NPC1	O15118-1.2	T461P	Pathogenic	0.581
NPC1	O15118-1.2	T461Q	Pathogenic	0.606
NPC1	O15118-1.2	T461R	Pathogenic	0.593
NPC1	O15118-1.2	T461S	Neutral	0.429
NPC1	O15118-1.2	T461V	Neutral	0.458
NPC1	O15118-1.2	T461W	Pathogenic	0.648
NPC1	O15118-1.2	T461Y	Pathogenic	0.712
NPC1	O15118-1.2	V462A	Pathogenic	0.514
NPC1	O15118-1.2	V462C	Pathogenic	0.635
NPC1	O15118-1.2	V462D	Pathogenic	0.671
NPC1	O15118-1.2	V462E	Pathogenic	0.576
NPC1	O15118-1.2	V462F	Pathogenic	0.624
NPC1	O15118-1.2	V462G	Pathogenic	0.773
NPC1	O15118-1.2	V462H	Pathogenic	0.732
NPC1	O15118-1.2	V462I	Neutral	0.248
NPC1	O15118-1.2	V462K	Pathogenic	0.586
NPC1	O15118-1.2	V462L	Neutral	0.425
NPC1	O15118-1.2	V462M	Neutral	0.463
NPC1	O15118-1.2	V462N	Pathogenic	0.676
NPC1	O15118-1.2	V462P	Pathogenic	0.695
NPC1	O15118-1.2	V462Q	Pathogenic	0.617
NPC1	O15118-1.2	V462R	Pathogenic	0.692
NPC1	O15118-1.2	V462S	Pathogenic	0.663
NPC1	O15118-1.2	V462T	Neutral	0.471
NPC1	O15118-1.2	V462W	Pathogenic	0.785
NPC1	O15118-1.2	V462Y	Pathogenic	0.656
NPC1	O15118-1.2	T463A	Pathogenic	0.606
NPC1	O15118-1.2	T463C	Pathogenic	0.617
NPC1	O15118-1.2	T463D	Pathogenic	0.586
NPC1	O15118-1.2	T463E	Pathogenic	0.616
NPC1	O15118-1.2	T463F	Pathogenic	0.691
NPC1	O15118-1.2	T463G	Pathogenic	0.777
NPC1	O15118-1.2	T463H	Pathogenic	0.763
NPC1	O15118-1.2	T463I	Pathogenic	0.586
NPC1	O15118-1.2	T463K	Pathogenic	0.626
NPC1	O15118-1.2	T463L	Pathogenic	0.594
NPC1	O15118-1.2	T463M	Pathogenic	0.631
NPC1	O15118-1.2	T463N	Pathogenic	0.505
NPC1	O15118-1.2	T463P	Pathogenic	0.632
NPC1	O15118-1.2	T463Q	Pathogenic	0.655
NPC1	O15118-1.2	T463R	Pathogenic	0.643
NPC1	O15118-1.2	T463S	Neutral	0.482
NPC1	O15118-1.2	T463V	Pathogenic	0.511
NPC1	O15118-1.2	T463W	Pathogenic	0.694
NPC1	O15118-1.2	T463Y	Pathogenic	0.753
NPC1	O15118-1.2	L464A	Pathogenic	0.937
NPC1	O15118-1.2	L464C	Pathogenic	0.943
NPC1	O15118-1.2	L464D	Pathogenic	0.966
NPC1	O15118-1.2	L464E	Pathogenic	0.948
NPC1	O15118-1.2	L464F	Pathogenic	0.922
NPC1	O15118-1.2	L464G	Pathogenic	0.98
NPC1	O15118-1.2	L464H	Pathogenic	0.957
NPC1	O15118-1.2	L464I	Pathogenic	0.836
NPC1	O15118-1.2	L464K	Pathogenic	0.915
NPC1	O15118-1.2	L464M	Pathogenic	0.819
NPC1	O15118-1.2	L464N	Pathogenic	0.952
NPC1	O15118-1.2	L464P	Pathogenic	0.97
NPC1	O15118-1.2	L464Q	Pathogenic	0.933
NPC1	O15118-1.2	L464R	Pathogenic	0.921
NPC1	O15118-1.2	L464S	Pathogenic	0.95
NPC1	O15118-1.2	L464T	Pathogenic	0.926
NPC1	O15118-1.2	L464V	Pathogenic	0.881
NPC1	O15118-1.2	L464W	Pathogenic	0.963
NPC1	O15118-1.2	L464Y	Pathogenic	0.936
NPC1	O15118-1.2	Q465A	Neutral	0.439
NPC1	O15118-1.2	Q465C	Pathogenic	0.547
NPC1	O15118-1.2	Q465D	Neutral	0.314
NPC1	O15118-1.2	Q465E	Neutral	0.165
NPC1	O15118-1.2	Q465F	Neutral	0.47
NPC1	O15118-1.2	Q465G	Pathogenic	0.589
NPC1	O15118-1.2	Q465H	Neutral	0.303
NPC1	O15118-1.2	Q465I	Neutral	0.452
NPC1	O15118-1.2	Q465K	Neutral	0.222
NPC1	O15118-1.2	Q465L	Neutral	0.367
NPC1	O15118-1.2	Q465M	Neutral	0.239
NPC1	O15118-1.2	Q465N	Neutral	0.319
NPC1	O15118-1.2	Q465P	Neutral	0.373
NPC1	O15118-1.2	Q465R	Neutral	0.235
NPC1	O15118-1.2	Q465S	Neutral	0.366
NPC1	O15118-1.2	Q465T	Neutral	0.405
NPC1	O15118-1.2	Q465V	Neutral	0.404
NPC1	O15118-1.2	Q465W	Neutral	0.38
NPC1	O15118-1.2	Q465Y	Neutral	0.359
NPC1	O15118-1.2	D466A	Pathogenic	0.927
NPC1	O15118-1.2	D466C	Pathogenic	0.93
NPC1	O15118-1.2	D466E	Pathogenic	0.781
NPC1	O15118-1.2	D466F	Pathogenic	0.928
NPC1	O15118-1.2	D466G	Pathogenic	0.915
NPC1	O15118-1.2	D466H	Pathogenic	0.903
NPC1	O15118-1.2	D466I	Pathogenic	0.923
NPC1	O15118-1.2	D466K	Pathogenic	0.928
NPC1	O15118-1.2	D466L	Pathogenic	0.948
NPC1	O15118-1.2	D466M	Pathogenic	0.935
NPC1	O15118-1.2	D466N	Pathogenic	0.828
NPC1	O15118-1.2	D466P	Pathogenic	0.867
NPC1	O15118-1.2	D466Q	Pathogenic	0.874
NPC1	O15118-1.2	D466R	Pathogenic	0.953
NPC1	O15118-1.2	D466S	Pathogenic	0.864
NPC1	O15118-1.2	D466T	Pathogenic	0.885
NPC1	O15118-1.2	D466V	Pathogenic	0.928
NPC1	O15118-1.2	D466W	Pathogenic	0.951
NPC1	O15118-1.2	D466Y	Pathogenic	0.946
NPC1	O15118-1.2	I467A	Pathogenic	0.919
NPC1	O15118-1.2	I467C	Pathogenic	0.926
NPC1	O15118-1.2	I467D	Pathogenic	0.937
NPC1	O15118-1.2	I467E	Pathogenic	0.933
NPC1	O15118-1.2	I467F	Pathogenic	0.905
NPC1	O15118-1.2	I467G	Pathogenic	0.973
NPC1	O15118-1.2	I467H	Pathogenic	0.944
NPC1	O15118-1.2	I467K	Pathogenic	0.923
NPC1	O15118-1.2	I467L	Pathogenic	0.8
NPC1	O15118-1.2	I467M	Pathogenic	0.834
NPC1	O15118-1.2	I467N	Pathogenic	0.938
NPC1	O15118-1.2	I467P	Pathogenic	0.961
NPC1	O15118-1.2	I467Q	Pathogenic	0.939
NPC1	O15118-1.2	I467R	Pathogenic	0.928
NPC1	O15118-1.2	I467S	Pathogenic	0.935
NPC1	O15118-1.2	I467T	Pathogenic	0.905
NPC1	O15118-1.2	I467V	Pathogenic	0.722
NPC1	O15118-1.2	I467W	Pathogenic	0.969
NPC1	O15118-1.2	I467Y	Pathogenic	0.917
NPC1	O15118-1.2	C468A	Pathogenic	0.955
NPC1	O15118-1.2	C468D	Pathogenic	0.978
NPC1	O15118-1.2	C468E	Pathogenic	0.987
NPC1	O15118-1.2	C468F	Pathogenic	0.982
NPC1	O15118-1.2	C468G	Pathogenic	0.986
NPC1	O15118-1.2	C468H	Pathogenic	0.986
NPC1	O15118-1.2	C468I	Pathogenic	0.971
NPC1	O15118-1.2	C468K	Pathogenic	0.981
NPC1	O15118-1.2	C468L	Pathogenic	0.972
NPC1	O15118-1.2	C468M	Pathogenic	0.976
NPC1	O15118-1.2	C468N	Pathogenic	0.979
NPC1	O15118-1.2	C468P	Pathogenic	0.986
NPC1	O15118-1.2	C468Q	Pathogenic	0.984
NPC1	O15118-1.2	C468R	Pathogenic	0.983
NPC1	O15118-1.2	C468S	Pathogenic	0.964
NPC1	O15118-1.2	C468T	Pathogenic	0.966
NPC1	O15118-1.2	C468V	Pathogenic	0.973
NPC1	O15118-1.2	C468W	Pathogenic	0.982
NPC1	O15118-1.2	C468Y	Pathogenic	0.986
NPC1	O15118-1.2	L469A	Pathogenic	0.561
NPC1	O15118-1.2	L469C	Pathogenic	0.588
NPC1	O15118-1.2	L469D	Pathogenic	0.711
NPC1	O15118-1.2	L469E	Pathogenic	0.61
NPC1	O15118-1.2	L469F	Pathogenic	0.504
NPC1	O15118-1.2	L469G	Pathogenic	0.805
NPC1	O15118-1.2	L469H	Pathogenic	0.657
NPC1	O15118-1.2	L469I	Neutral	0.304
NPC1	O15118-1.2	L469K	Neutral	0.48
NPC1	O15118-1.2	L469M	Neutral	0.279
NPC1	O15118-1.2	L469N	Pathogenic	0.632
NPC1	O15118-1.2	L469P	Pathogenic	0.734
NPC1	O15118-1.2	L469Q	Pathogenic	0.543
NPC1	O15118-1.2	L469R	Neutral	0.499
NPC1	O15118-1.2	L469S	Pathogenic	0.618
NPC1	O15118-1.2	L469T	Pathogenic	0.518
NPC1	O15118-1.2	L469V	Neutral	0.388
NPC1	O15118-1.2	L469W	Pathogenic	0.691
NPC1	O15118-1.2	L469Y	Pathogenic	0.555
NPC1	O15118-1.2	A470C	Pathogenic	0.786
NPC1	O15118-1.2	A470D	Pathogenic	0.877
NPC1	O15118-1.2	A470E	Pathogenic	0.85
NPC1	O15118-1.2	A470F	Pathogenic	0.891
NPC1	O15118-1.2	A470G	Pathogenic	0.805
NPC1	O15118-1.2	A470H	Pathogenic	0.919
NPC1	O15118-1.2	A470I	Pathogenic	0.838
NPC1	O15118-1.2	A470K	Pathogenic	0.855
NPC1	O15118-1.2	A470L	Pathogenic	0.842
NPC1	O15118-1.2	A470M	Pathogenic	0.862
NPC1	O15118-1.2	A470N	Pathogenic	0.886
NPC1	O15118-1.2	A470P	Pathogenic	0.858
NPC1	O15118-1.2	A470Q	Pathogenic	0.87
NPC1	O15118-1.2	A470R	Pathogenic	0.864
NPC1	O15118-1.2	A470S	Pathogenic	0.72
NPC1	O15118-1.2	A470T	Pathogenic	0.825
NPC1	O15118-1.2	A470V	Pathogenic	0.792
NPC1	O15118-1.2	A470W	Pathogenic	0.924
NPC1	O15118-1.2	A470Y	Pathogenic	0.918
NPC1	O15118-1.2	P471A	Pathogenic	0.968
NPC1	O15118-1.2	P471C	Pathogenic	0.984
NPC1	O15118-1.2	P471D	Pathogenic	0.949
NPC1	O15118-1.2	P471E	Pathogenic	0.956
NPC1	O15118-1.2	P471F	Pathogenic	0.989
NPC1	O15118-1.2	P471G	Pathogenic	0.978
NPC1	O15118-1.2	P471H	Pathogenic	0.977
NPC1	O15118-1.2	P471I	Pathogenic	0.982
NPC1	O15118-1.2	P471K	Pathogenic	0.957
NPC1	O15118-1.2	P471L	Pathogenic	0.983
NPC1	O15118-1.2	P471M	Pathogenic	0.979
NPC1	O15118-1.2	P471N	Pathogenic	0.967
NPC1	O15118-1.2	P471Q	Pathogenic	0.962
NPC1	O15118-1.2	P471R	Pathogenic	0.973
NPC1	O15118-1.2	P471S	Pathogenic	0.963
NPC1	O15118-1.2	P471T	Pathogenic	0.964
NPC1	O15118-1.2	P471V	Pathogenic	0.976
NPC1	O15118-1.2	P471W	Pathogenic	0.989
NPC1	O15118-1.2	P471Y	Pathogenic	0.988
NPC1	O15118-1.2	L472A	Pathogenic	0.932
NPC1	O15118-1.2	L472C	Pathogenic	0.939
NPC1	O15118-1.2	L472D	Pathogenic	0.964
NPC1	O15118-1.2	L472E	Pathogenic	0.944
NPC1	O15118-1.2	L472F	Pathogenic	0.916
NPC1	O15118-1.2	L472G	Pathogenic	0.978
NPC1	O15118-1.2	L472H	Pathogenic	0.954
NPC1	O15118-1.2	L472I	Pathogenic	0.825
NPC1	O15118-1.2	L472K	Pathogenic	0.909
NPC1	O15118-1.2	L472M	Pathogenic	0.806
NPC1	O15118-1.2	L472N	Pathogenic	0.949
NPC1	O15118-1.2	L472P	Pathogenic	0.967
NPC1	O15118-1.2	L472Q	Pathogenic	0.927
NPC1	O15118-1.2	L472R	Pathogenic	0.915
NPC1	O15118-1.2	L472S	Pathogenic	0.946
NPC1	O15118-1.2	L472T	Pathogenic	0.92
NPC1	O15118-1.2	L472V	Pathogenic	0.872
NPC1	O15118-1.2	L472W	Pathogenic	0.96
NPC1	O15118-1.2	L472Y	Pathogenic	0.931
NPC1	O15118-1.2	S473A	Neutral	0.285
NPC1	O15118-1.2	S473C	Neutral	0.418
NPC1	O15118-1.2	S473D	Neutral	0.356
NPC1	O15118-1.2	S473E	Neutral	0.392
NPC1	O15118-1.2	S473F	Pathogenic	0.521
NPC1	O15118-1.2	S473G	Neutral	0.421
NPC1	O15118-1.2	S473H	Pathogenic	0.536
NPC1	O15118-1.2	S473I	Pathogenic	0.503
NPC1	O15118-1.2	S473K	Neutral	0.402
NPC1	O15118-1.2	S473L	Pathogenic	0.511
NPC1	O15118-1.2	S473M	Neutral	0.454
NPC1	O15118-1.2	S473N	Neutral	0.291
NPC1	O15118-1.2	S473P	Neutral	0.445
NPC1	O15118-1.2	S473Q	Neutral	0.433
NPC1	O15118-1.2	S473R	Pathogenic	0.515
NPC1	O15118-1.2	S473T	Neutral	0.306
NPC1	O15118-1.2	S473V	Pathogenic	0.523
NPC1	O15118-1.2	S473W	Pathogenic	0.619
NPC1	O15118-1.2	S473Y	Pathogenic	0.597
NPC1	O15118-1.2	P474A	Pathogenic	0.894
NPC1	O15118-1.2	P474C	Pathogenic	0.945
NPC1	O15118-1.2	P474D	Pathogenic	0.838
NPC1	O15118-1.2	P474E	Pathogenic	0.858
NPC1	O15118-1.2	P474F	Pathogenic	0.961
NPC1	O15118-1.2	P474G	Pathogenic	0.927
NPC1	O15118-1.2	P474H	Pathogenic	0.924
NPC1	O15118-1.2	P474I	Pathogenic	0.94
NPC1	O15118-1.2	P474K	Pathogenic	0.863
NPC1	O15118-1.2	P474L	Pathogenic	0.942
NPC1	O15118-1.2	P474M	Pathogenic	0.928
NPC1	O15118-1.2	P474N	Pathogenic	0.893
NPC1	O15118-1.2	P474Q	Pathogenic	0.877
NPC1	O15118-1.2	P474R	Pathogenic	0.909
NPC1	O15118-1.2	P474S	Pathogenic	0.879
NPC1	O15118-1.2	P474T	Pathogenic	0.881
NPC1	O15118-1.2	P474V	Pathogenic	0.92
NPC1	O15118-1.2	P474W	Pathogenic	0.962
NPC1	O15118-1.2	P474Y	Pathogenic	0.958
NPC1	O15118-1.2	Y475A	Pathogenic	0.686
NPC1	O15118-1.2	Y475C	Pathogenic	0.706
NPC1	O15118-1.2	Y475D	Pathogenic	0.66
NPC1	O15118-1.2	Y475E	Pathogenic	0.553
NPC1	O15118-1.2	Y475F	Neutral	0.166
NPC1	O15118-1.2	Y475G	Pathogenic	0.765
NPC1	O15118-1.2	Y475H	Neutral	0.244
NPC1	O15118-1.2	Y475I	Neutral	0.497
NPC1	O15118-1.2	Y475K	Neutral	0.485
NPC1	O15118-1.2	Y475L	Pathogenic	0.505
NPC1	O15118-1.2	Y475M	Pathogenic	0.544
NPC1	O15118-1.2	Y475N	Pathogenic	0.575
NPC1	O15118-1.2	Y475P	Pathogenic	0.762
NPC1	O15118-1.2	Y475Q	Neutral	0.484
NPC1	O15118-1.2	Y475R	Neutral	0.485
NPC1	O15118-1.2	Y475S	Pathogenic	0.653
NPC1	O15118-1.2	Y475T	Pathogenic	0.647
NPC1	O15118-1.2	Y475V	Pathogenic	0.574
NPC1	O15118-1.2	Y475W	Neutral	0.216
NPC1	O15118-1.2	N476A	Pathogenic	0.8
NPC1	O15118-1.2	N476C	Pathogenic	0.807
NPC1	O15118-1.2	N476D	Pathogenic	0.581
NPC1	O15118-1.2	N476E	Pathogenic	0.691
NPC1	O15118-1.2	N476F	Pathogenic	0.792
NPC1	O15118-1.2	N476G	Pathogenic	0.696
NPC1	O15118-1.2	N476H	Pathogenic	0.56
NPC1	O15118-1.2	N476I	Pathogenic	0.78
NPC1	O15118-1.2	N476K	Pathogenic	0.7
NPC1	O15118-1.2	N476L	Pathogenic	0.786
NPC1	O15118-1.2	N476M	Pathogenic	0.745
NPC1	O15118-1.2	N476P	Pathogenic	0.752
NPC1	O15118-1.2	N476Q	Pathogenic	0.673
NPC1	O15118-1.2	N476R	Pathogenic	0.715
NPC1	O15118-1.2	N476S	Pathogenic	0.576
NPC1	O15118-1.2	N476T	Pathogenic	0.616
NPC1	O15118-1.2	N476V	Pathogenic	0.794
NPC1	O15118-1.2	N476W	Pathogenic	0.851
NPC1	O15118-1.2	N476Y	Pathogenic	0.78
NPC1	O15118-1.2	T477A	Neutral	0.198
NPC1	O15118-1.2	T477C	Neutral	0.206
NPC1	O15118-1.2	T477D	Neutral	0.185
NPC1	O15118-1.2	T477E	Neutral	0.205
NPC1	O15118-1.2	T477F	Neutral	0.265
NPC1	O15118-1.2	T477G	Neutral	0.359
NPC1	O15118-1.2	T477H	Neutral	0.341
NPC1	O15118-1.2	T477I	Neutral	0.186
NPC1	O15118-1.2	T477K	Neutral	0.212
NPC1	O15118-1.2	T477L	Neutral	0.191
NPC1	O15118-1.2	T477M	Neutral	0.216
NPC1	O15118-1.2	T477N	Neutral	0.141
NPC1	O15118-1.2	T477P	Neutral	0.216
NPC1	O15118-1.2	T477Q	Neutral	0.234
NPC1	O15118-1.2	T477R	Neutral	0.225
NPC1	O15118-1.2	T477S	Neutral	0.13
NPC1	O15118-1.2	T477V	Neutral	0.144
NPC1	O15118-1.2	T477W	Neutral	0.268
NPC1	O15118-1.2	T477Y	Neutral	0.33
NPC1	O15118-1.2	N478A	Neutral	0.386
NPC1	O15118-1.2	N478C	Neutral	0.397
NPC1	O15118-1.2	N478D	Neutral	0.179
NPC1	O15118-1.2	N478E	Neutral	0.26
NPC1	O15118-1.2	N478F	Neutral	0.375
NPC1	O15118-1.2	N478G	Neutral	0.265
NPC1	O15118-1.2	N478H	Neutral	0.167
NPC1	O15118-1.2	N478I	Neutral	0.358
NPC1	O15118-1.2	N478K	Neutral	0.268
NPC1	O15118-1.2	N478L	Neutral	0.366
NPC1	O15118-1.2	N478M	Neutral	0.315
NPC1	O15118-1.2	N478P	Neutral	0.323
NPC1	O15118-1.2	N478Q	Neutral	0.244
NPC1	O15118-1.2	N478R	Neutral	0.283
NPC1	O15118-1.2	N478S	Neutral	0.176
NPC1	O15118-1.2	N478T	Neutral	0.201
NPC1	O15118-1.2	N478V	Neutral	0.377
NPC1	O15118-1.2	N478W	Neutral	0.473
NPC1	O15118-1.2	N478Y	Neutral	0.358
NPC1	O15118-1.2	C479A	Pathogenic	0.955
NPC1	O15118-1.2	C479D	Pathogenic	0.978
NPC1	O15118-1.2	C479E	Pathogenic	0.987
NPC1	O15118-1.2	C479F	Pathogenic	0.982
NPC1	O15118-1.2	C479G	Pathogenic	0.986
NPC1	O15118-1.2	C479H	Pathogenic	0.986
NPC1	O15118-1.2	C479I	Pathogenic	0.971
NPC1	O15118-1.2	C479K	Pathogenic	0.981
NPC1	O15118-1.2	C479L	Pathogenic	0.972
NPC1	O15118-1.2	C479M	Pathogenic	0.976
NPC1	O15118-1.2	C479N	Pathogenic	0.979
NPC1	O15118-1.2	C479P	Pathogenic	0.986
NPC1	O15118-1.2	C479Q	Pathogenic	0.984
NPC1	O15118-1.2	C479R	Pathogenic	0.983
NPC1	O15118-1.2	C479S	Pathogenic	0.964
NPC1	O15118-1.2	C479T	Pathogenic	0.966
NPC1	O15118-1.2	C479V	Pathogenic	0.973
NPC1	O15118-1.2	C479W	Pathogenic	0.982
NPC1	O15118-1.2	C479Y	Pathogenic	0.986
NPC1	O15118-1.2	T480A	Pathogenic	0.702
NPC1	O15118-1.2	T480C	Pathogenic	0.712
NPC1	O15118-1.2	T480D	Pathogenic	0.684
NPC1	O15118-1.2	T480E	Pathogenic	0.711
NPC1	O15118-1.2	T480F	Pathogenic	0.774
NPC1	O15118-1.2	T480G	Pathogenic	0.842
NPC1	O15118-1.2	T480H	Pathogenic	0.832
NPC1	O15118-1.2	T480I	Pathogenic	0.685
NPC1	O15118-1.2	T480K	Pathogenic	0.72
NPC1	O15118-1.2	T480L	Pathogenic	0.692
NPC1	O15118-1.2	T480M	Pathogenic	0.724
NPC1	O15118-1.2	T480N	Pathogenic	0.611
NPC1	O15118-1.2	T480P	Pathogenic	0.725
NPC1	O15118-1.2	T480Q	Pathogenic	0.745
NPC1	O15118-1.2	T480R	Pathogenic	0.734
NPC1	O15118-1.2	T480S	Pathogenic	0.588
NPC1	O15118-1.2	T480V	Pathogenic	0.616
NPC1	O15118-1.2	T480W	Pathogenic	0.777
NPC1	O15118-1.2	T480Y	Pathogenic	0.824
NPC1	O15118-1.2	I481A	Pathogenic	0.873
NPC1	O15118-1.2	I481C	Pathogenic	0.885
NPC1	O15118-1.2	I481D	Pathogenic	0.9
NPC1	O15118-1.2	I481E	Pathogenic	0.894
NPC1	O15118-1.2	I481F	Pathogenic	0.853
NPC1	O15118-1.2	I481G	Pathogenic	0.957
NPC1	O15118-1.2	I481H	Pathogenic	0.912
NPC1	O15118-1.2	I481K	Pathogenic	0.88
NPC1	O15118-1.2	I481L	Pathogenic	0.709
NPC1	O15118-1.2	I481M	Pathogenic	0.754
NPC1	O15118-1.2	I481N	Pathogenic	0.902
NPC1	O15118-1.2	I481P	Pathogenic	0.937
NPC1	O15118-1.2	I481Q	Pathogenic	0.904
NPC1	O15118-1.2	I481R	Pathogenic	0.888
NPC1	O15118-1.2	I481S	Pathogenic	0.897
NPC1	O15118-1.2	I481T	Pathogenic	0.853
NPC1	O15118-1.2	I481V	Pathogenic	0.613
NPC1	O15118-1.2	I481W	Pathogenic	0.95
NPC1	O15118-1.2	I481Y	Pathogenic	0.87
NPC1	O15118-1.2	L482A	Neutral	0.494
NPC1	O15118-1.2	L482C	Pathogenic	0.522
NPC1	O15118-1.2	L482D	Pathogenic	0.653
NPC1	O15118-1.2	L482E	Pathogenic	0.545
NPC1	O15118-1.2	L482F	Neutral	0.437
NPC1	O15118-1.2	L482G	Pathogenic	0.759
NPC1	O15118-1.2	L482H	Pathogenic	0.594
NPC1	O15118-1.2	L482I	Neutral	0.251
NPC1	O15118-1.2	L482K	Neutral	0.414
NPC1	O15118-1.2	L482M	Neutral	0.228
NPC1	O15118-1.2	L482N	Pathogenic	0.568
NPC1	O15118-1.2	L482P	Pathogenic	0.678
NPC1	O15118-1.2	L482Q	Neutral	0.476
NPC1	O15118-1.2	L482R	Neutral	0.432
NPC1	O15118-1.2	L482S	Pathogenic	0.553
NPC1	O15118-1.2	L482T	Neutral	0.451
NPC1	O15118-1.2	L482V	Neutral	0.327
NPC1	O15118-1.2	L482W	Pathogenic	0.631
NPC1	O15118-1.2	L482Y	Neutral	0.488
NPC1	O15118-1.2	S483A	Pathogenic	0.914
NPC1	O15118-1.2	S483C	Pathogenic	0.95
NPC1	O15118-1.2	S483D	Pathogenic	0.936
NPC1	O15118-1.2	S483E	Pathogenic	0.945
NPC1	O15118-1.2	S483F	Pathogenic	0.966
NPC1	O15118-1.2	S483G	Pathogenic	0.951
NPC1	O15118-1.2	S483H	Pathogenic	0.968
NPC1	O15118-1.2	S483I	Pathogenic	0.964
NPC1	O15118-1.2	S483K	Pathogenic	0.947
NPC1	O15118-1.2	S483L	Pathogenic	0.965
NPC1	O15118-1.2	S483M	Pathogenic	0.957
NPC1	O15118-1.2	S483N	Pathogenic	0.916
NPC1	O15118-1.2	S483P	Pathogenic	0.955
NPC1	O15118-1.2	S483Q	Pathogenic	0.953
NPC1	O15118-1.2	S483R	Pathogenic	0.966
NPC1	O15118-1.2	S483T	Pathogenic	0.921
NPC1	O15118-1.2	S483V	Pathogenic	0.967
NPC1	O15118-1.2	S483W	Pathogenic	0.977
NPC1	O15118-1.2	S483Y	Pathogenic	0.975
NPC1	O15118-1.2	V484A	Pathogenic	0.685
NPC1	O15118-1.2	V484C	Pathogenic	0.781
NPC1	O15118-1.2	V484D	Pathogenic	0.807
NPC1	O15118-1.2	V484E	Pathogenic	0.737
NPC1	O15118-1.2	V484F	Pathogenic	0.773
NPC1	O15118-1.2	V484G	Pathogenic	0.875
NPC1	O15118-1.2	V484H	Pathogenic	0.849
NPC1	O15118-1.2	V484I	Neutral	0.404
NPC1	O15118-1.2	V484K	Pathogenic	0.745
NPC1	O15118-1.2	V484L	Pathogenic	0.603
NPC1	O15118-1.2	V484M	Pathogenic	0.64
NPC1	O15118-1.2	V484N	Pathogenic	0.811
NPC1	O15118-1.2	V484P	Pathogenic	0.824
NPC1	O15118-1.2	V484Q	Pathogenic	0.768
NPC1	O15118-1.2	V484R	Pathogenic	0.822
NPC1	O15118-1.2	V484S	Pathogenic	0.802
NPC1	O15118-1.2	V484T	Pathogenic	0.646
NPC1	O15118-1.2	V484W	Pathogenic	0.882
NPC1	O15118-1.2	V484Y	Pathogenic	0.797
NPC1	O15118-1.2	L485A	Pathogenic	0.693
NPC1	O15118-1.2	L485C	Pathogenic	0.715
NPC1	O15118-1.2	L485D	Pathogenic	0.813
NPC1	O15118-1.2	L485E	Pathogenic	0.734
NPC1	O15118-1.2	L485F	Pathogenic	0.642
NPC1	O15118-1.2	L485G	Pathogenic	0.879
NPC1	O15118-1.2	L485H	Pathogenic	0.772
NPC1	O15118-1.2	L485I	Neutral	0.435
NPC1	O15118-1.2	L485K	Pathogenic	0.62
NPC1	O15118-1.2	L485M	Neutral	0.406
NPC1	O15118-1.2	L485N	Pathogenic	0.752
NPC1	O15118-1.2	L485P	Pathogenic	0.829
NPC1	O15118-1.2	L485Q	Pathogenic	0.677
NPC1	O15118-1.2	L485R	Pathogenic	0.637
NPC1	O15118-1.2	L485S	Pathogenic	0.74
NPC1	O15118-1.2	L485T	Pathogenic	0.654
NPC1	O15118-1.2	L485V	Pathogenic	0.528
NPC1	O15118-1.2	L485W	Pathogenic	0.797
NPC1	O15118-1.2	L485Y	Pathogenic	0.687
NPC1	O15118-1.2	N486A	Pathogenic	0.841
NPC1	O15118-1.2	N486C	Pathogenic	0.847
NPC1	O15118-1.2	N486D	Pathogenic	0.647
NPC1	O15118-1.2	N486E	Pathogenic	0.747
NPC1	O15118-1.2	N486F	Pathogenic	0.834
NPC1	O15118-1.2	N486G	Pathogenic	0.752
NPC1	O15118-1.2	N486H	Pathogenic	0.628
NPC1	O15118-1.2	N486I	Pathogenic	0.824
NPC1	O15118-1.2	N486K	Pathogenic	0.755
NPC1	O15118-1.2	N486L	Pathogenic	0.829
NPC1	O15118-1.2	N486M	Pathogenic	0.794
NPC1	O15118-1.2	N486P	Pathogenic	0.8
NPC1	O15118-1.2	N486Q	Pathogenic	0.731
NPC1	O15118-1.2	N486R	Pathogenic	0.768
NPC1	O15118-1.2	N486S	Pathogenic	0.642
NPC1	O15118-1.2	N486T	Pathogenic	0.68
NPC1	O15118-1.2	N486V	Pathogenic	0.836
NPC1	O15118-1.2	N486W	Pathogenic	0.883
NPC1	O15118-1.2	N486Y	Pathogenic	0.824
NPC1	O15118-1.2	Y487A	Pathogenic	0.978
NPC1	O15118-1.2	Y487C	Pathogenic	0.98
NPC1	O15118-1.2	Y487D	Pathogenic	0.975
NPC1	O15118-1.2	Y487E	Pathogenic	0.961
NPC1	O15118-1.2	Y487F	Pathogenic	0.799
NPC1	O15118-1.2	Y487G	Pathogenic	0.985
NPC1	O15118-1.2	Y487H	Pathogenic	0.867
NPC1	O15118-1.2	Y487I	Pathogenic	0.952
NPC1	O15118-1.2	Y487K	Pathogenic	0.95
NPC1	O15118-1.2	Y487L	Pathogenic	0.954
NPC1	O15118-1.2	Y487M	Pathogenic	0.96
NPC1	O15118-1.2	Y487N	Pathogenic	0.965
NPC1	O15118-1.2	Y487P	Pathogenic	0.985
NPC1	O15118-1.2	Y487Q	Pathogenic	0.95
NPC1	O15118-1.2	Y487R	Pathogenic	0.95
NPC1	O15118-1.2	Y487S	Pathogenic	0.974
NPC1	O15118-1.2	Y487T	Pathogenic	0.974
NPC1	O15118-1.2	Y487V	Pathogenic	0.964
NPC1	O15118-1.2	Y487W	Pathogenic	0.847
NPC1	O15118-1.2	F488A	Pathogenic	0.898
NPC1	O15118-1.2	F488C	Pathogenic	0.907
NPC1	O15118-1.2	F488D	Pathogenic	0.886
NPC1	O15118-1.2	F488E	Pathogenic	0.88
NPC1	O15118-1.2	F488G	Pathogenic	0.929
NPC1	O15118-1.2	F488H	Pathogenic	0.805
NPC1	O15118-1.2	F488I	Pathogenic	0.824
NPC1	O15118-1.2	F488K	Pathogenic	0.847
NPC1	O15118-1.2	F488L	Pathogenic	0.82
NPC1	O15118-1.2	F488M	Pathogenic	0.796
NPC1	O15118-1.2	F488N	Pathogenic	0.889
NPC1	O15118-1.2	F488P	Pathogenic	0.95
NPC1	O15118-1.2	F488Q	Pathogenic	0.891
NPC1	O15118-1.2	F488R	Pathogenic	0.857
NPC1	O15118-1.2	F488S	Pathogenic	0.883
NPC1	O15118-1.2	F488T	Pathogenic	0.88
NPC1	O15118-1.2	F488V	Pathogenic	0.865
NPC1	O15118-1.2	F488W	Pathogenic	0.752
NPC1	O15118-1.2	F488Y	Pathogenic	0.521
NPC1	O15118-1.2	Q489A	Pathogenic	0.954
NPC1	O15118-1.2	Q489C	Pathogenic	0.97
NPC1	O15118-1.2	Q489D	Pathogenic	0.924
NPC1	O15118-1.2	Q489E	Pathogenic	0.841
NPC1	O15118-1.2	Q489F	Pathogenic	0.959
NPC1	O15118-1.2	Q489G	Pathogenic	0.974
NPC1	O15118-1.2	Q489H	Pathogenic	0.921
NPC1	O15118-1.2	Q489I	Pathogenic	0.956
NPC1	O15118-1.2	Q489K	Pathogenic	0.884
NPC1	O15118-1.2	Q489L	Pathogenic	0.939
NPC1	O15118-1.2	Q489M	Pathogenic	0.893
NPC1	O15118-1.2	Q489N	Pathogenic	0.926
NPC1	O15118-1.2	Q489P	Pathogenic	0.941
NPC1	O15118-1.2	Q489R	Pathogenic	0.891
NPC1	O15118-1.2	Q489S	Pathogenic	0.939
NPC1	O15118-1.2	Q489T	Pathogenic	0.948
NPC1	O15118-1.2	Q489V	Pathogenic	0.947
NPC1	O15118-1.2	Q489W	Pathogenic	0.942
NPC1	O15118-1.2	Q489Y	Pathogenic	0.937
NPC1	O15118-1.2	N490A	Pathogenic	0.908
NPC1	O15118-1.2	N490C	Pathogenic	0.911
NPC1	O15118-1.2	N490D	Pathogenic	0.773
NPC1	O15118-1.2	N490E	Pathogenic	0.846
NPC1	O15118-1.2	N490F	Pathogenic	0.904
NPC1	O15118-1.2	N490G	Pathogenic	0.849
NPC1	O15118-1.2	N490H	Pathogenic	0.758
NPC1	O15118-1.2	N490I	Pathogenic	0.897
NPC1	O15118-1.2	N490K	Pathogenic	0.851
NPC1	O15118-1.2	N490L	Pathogenic	0.9
NPC1	O15118-1.2	N490M	Pathogenic	0.878
NPC1	O15118-1.2	N490P	Pathogenic	0.882
NPC1	O15118-1.2	N490Q	Pathogenic	0.835
NPC1	O15118-1.2	N490R	Pathogenic	0.861
NPC1	O15118-1.2	N490S	Pathogenic	0.769
NPC1	O15118-1.2	N490T	Pathogenic	0.798
NPC1	O15118-1.2	N490V	Pathogenic	0.904
NPC1	O15118-1.2	N490W	Pathogenic	0.933
NPC1	O15118-1.2	N490Y	Pathogenic	0.897
NPC1	O15118-1.2	S491A	Pathogenic	0.62
NPC1	O15118-1.2	S491C	Pathogenic	0.746
NPC1	O15118-1.2	S491D	Pathogenic	0.694
NPC1	O15118-1.2	S491E	Pathogenic	0.725
NPC1	O15118-1.2	S491F	Pathogenic	0.816
NPC1	O15118-1.2	S491G	Pathogenic	0.749
NPC1	O15118-1.2	S491H	Pathogenic	0.825
NPC1	O15118-1.2	S491I	Pathogenic	0.805
NPC1	O15118-1.2	S491K	Pathogenic	0.733
NPC1	O15118-1.2	S491L	Pathogenic	0.811
NPC1	O15118-1.2	S491M	Pathogenic	0.773
NPC1	O15118-1.2	S491N	Pathogenic	0.627
NPC1	O15118-1.2	S491P	Pathogenic	0.767
NPC1	O15118-1.2	S491Q	Pathogenic	0.757
NPC1	O15118-1.2	S491R	Pathogenic	0.813
NPC1	O15118-1.2	S491T	Pathogenic	0.643
NPC1	O15118-1.2	S491V	Pathogenic	0.818
NPC1	O15118-1.2	S491W	Pathogenic	0.869
NPC1	O15118-1.2	S491Y	Pathogenic	0.859
NPC1	O15118-1.2	H492A	Pathogenic	0.732
NPC1	O15118-1.2	H492C	Pathogenic	0.741
NPC1	O15118-1.2	H492D	Pathogenic	0.558
NPC1	O15118-1.2	H492E	Neutral	0.446
NPC1	O15118-1.2	H492F	Neutral	0.48
NPC1	O15118-1.2	H492G	Pathogenic	0.757
NPC1	O15118-1.2	H492I	Pathogenic	0.65
NPC1	O15118-1.2	H492K	Pathogenic	0.525
NPC1	O15118-1.2	H492L	Pathogenic	0.658
NPC1	O15118-1.2	H492M	Pathogenic	0.605
NPC1	O15118-1.2	H492N	Neutral	0.374
NPC1	O15118-1.2	H492P	Pathogenic	0.675
NPC1	O15118-1.2	H492Q	Neutral	0.473
NPC1	O15118-1.2	H492R	Neutral	0.447
NPC1	O15118-1.2	H492S	Pathogenic	0.642
NPC1	O15118-1.2	H492T	Pathogenic	0.704
NPC1	O15118-1.2	H492V	Pathogenic	0.702
NPC1	O15118-1.2	H492W	Pathogenic	0.58
NPC1	O15118-1.2	H492Y	Neutral	0.284
NPC1	O15118-1.2	S493A	Neutral	0.241
NPC1	O15118-1.2	S493C	Neutral	0.364
NPC1	O15118-1.2	S493D	Neutral	0.306
NPC1	O15118-1.2	S493E	Neutral	0.34
NPC1	O15118-1.2	S493F	Neutral	0.464
NPC1	O15118-1.2	S493G	Neutral	0.367
NPC1	O15118-1.2	S493H	Neutral	0.48
NPC1	O15118-1.2	S493I	Neutral	0.447
NPC1	O15118-1.2	S493K	Neutral	0.349
NPC1	O15118-1.2	S493L	Neutral	0.455
NPC1	O15118-1.2	S493M	Neutral	0.399
NPC1	O15118-1.2	S493N	Neutral	0.247
NPC1	O15118-1.2	S493P	Neutral	0.391
NPC1	O15118-1.2	S493Q	Neutral	0.379
NPC1	O15118-1.2	S493R	Neutral	0.459
NPC1	O15118-1.2	S493T	Neutral	0.26
NPC1	O15118-1.2	S493V	Neutral	0.466
NPC1	O15118-1.2	S493W	Pathogenic	0.564
NPC1	O15118-1.2	S493Y	Pathogenic	0.542
NPC1	O15118-1.2	V494A	Neutral	0.186
NPC1	O15118-1.2	V494C	Neutral	0.273
NPC1	O15118-1.2	V494D	Neutral	0.306
NPC1	O15118-1.2	V494E	Neutral	0.228
NPC1	O15118-1.2	V494F	Neutral	0.264
NPC1	O15118-1.2	V494G	Neutral	0.425
NPC1	O15118-1.2	V494H	Neutral	0.372
NPC1	O15118-1.2	V494I	Neutral	0.067
NPC1	O15118-1.2	V494K	Neutral	0.235
NPC1	O15118-1.2	V494L	Neutral	0.138
NPC1	O15118-1.2	V494M	Neutral	0.158
NPC1	O15118-1.2	V494N	Neutral	0.311
NPC1	O15118-1.2	V494P	Neutral	0.331
NPC1	O15118-1.2	V494Q	Neutral	0.259
NPC1	O15118-1.2	V494R	Neutral	0.327
NPC1	O15118-1.2	V494S	Neutral	0.299
NPC1	O15118-1.2	V494T	Neutral	0.161
NPC1	O15118-1.2	V494W	Neutral	0.441
NPC1	O15118-1.2	V494Y	Neutral	0.293
NPC1	O15118-1.2	L495A	Pathogenic	0.807
NPC1	O15118-1.2	L495C	Pathogenic	0.824
NPC1	O15118-1.2	L495D	Pathogenic	0.89
NPC1	O15118-1.2	L495E	Pathogenic	0.837
NPC1	O15118-1.2	L495F	Pathogenic	0.769
NPC1	O15118-1.2	L495G	Pathogenic	0.931
NPC1	O15118-1.2	L495H	Pathogenic	0.863
NPC1	O15118-1.2	L495I	Pathogenic	0.589
NPC1	O15118-1.2	L495K	Pathogenic	0.752
NPC1	O15118-1.2	L495M	Pathogenic	0.559
NPC1	O15118-1.2	L495N	Pathogenic	0.849
NPC1	O15118-1.2	L495P	Pathogenic	0.9
NPC1	O15118-1.2	L495Q	Pathogenic	0.796
NPC1	O15118-1.2	L495R	Pathogenic	0.765
NPC1	O15118-1.2	L495S	Pathogenic	0.841
NPC1	O15118-1.2	L495T	Pathogenic	0.779
NPC1	O15118-1.2	L495V	Pathogenic	0.676
NPC1	O15118-1.2	L495W	Pathogenic	0.88
NPC1	O15118-1.2	L495Y	Pathogenic	0.803
NPC1	O15118-1.2	D496A	Pathogenic	0.86
NPC1	O15118-1.2	D496C	Pathogenic	0.866
NPC1	O15118-1.2	D496E	Pathogenic	0.635
NPC1	O15118-1.2	D496F	Pathogenic	0.862
NPC1	O15118-1.2	D496G	Pathogenic	0.839
NPC1	O15118-1.2	D496H	Pathogenic	0.819
NPC1	O15118-1.2	D496I	Pathogenic	0.853
NPC1	O15118-1.2	D496K	Pathogenic	0.863
NPC1	O15118-1.2	D496L	Pathogenic	0.898
NPC1	O15118-1.2	D496M	Pathogenic	0.876
NPC1	O15118-1.2	D496N	Pathogenic	0.7
NPC1	O15118-1.2	D496P	Pathogenic	0.761
NPC1	O15118-1.2	D496Q	Pathogenic	0.771
NPC1	O15118-1.2	D496R	Pathogenic	0.909
NPC1	O15118-1.2	D496S	Pathogenic	0.755
NPC1	O15118-1.2	D496T	Pathogenic	0.788
NPC1	O15118-1.2	D496V	Pathogenic	0.863
NPC1	O15118-1.2	D496W	Pathogenic	0.903
NPC1	O15118-1.2	D496Y	Pathogenic	0.895
NPC1	O15118-1.2	H497A	Pathogenic	0.621
NPC1	O15118-1.2	H497C	Pathogenic	0.632
NPC1	O15118-1.2	H497D	Neutral	0.431
NPC1	O15118-1.2	H497E	Neutral	0.326
NPC1	O15118-1.2	H497F	Neutral	0.357
NPC1	O15118-1.2	H497G	Pathogenic	0.651
NPC1	O15118-1.2	H497I	Pathogenic	0.528
NPC1	O15118-1.2	H497K	Neutral	0.399
NPC1	O15118-1.2	H497L	Pathogenic	0.536
NPC1	O15118-1.2	H497M	Neutral	0.479
NPC1	O15118-1.2	H497N	Neutral	0.264
NPC1	O15118-1.2	H497P	Pathogenic	0.555
NPC1	O15118-1.2	H497Q	Neutral	0.35
NPC1	O15118-1.2	H497R	Neutral	0.327
NPC1	O15118-1.2	H497S	Pathogenic	0.519
NPC1	O15118-1.2	H497T	Pathogenic	0.588
NPC1	O15118-1.2	H497V	Pathogenic	0.586
NPC1	O15118-1.2	H497W	Neutral	0.453
NPC1	O15118-1.2	H497Y	Neutral	0.192
NPC1	O15118-1.2	K498A	Neutral	0.15
NPC1	O15118-1.2	K498C	Neutral	0.213
NPC1	O15118-1.2	K498D	Neutral	0.179
NPC1	O15118-1.2	K498E	Neutral	0.08
NPC1	O15118-1.2	K498F	Neutral	0.134
NPC1	O15118-1.2	K498G	Neutral	0.243
NPC1	O15118-1.2	K498H	Neutral	0.121
NPC1	O15118-1.2	K498I	Neutral	0.141
NPC1	O15118-1.2	K498L	Neutral	0.103
NPC1	O15118-1.2	K498M	Neutral	0.084
NPC1	O15118-1.2	K498N	Neutral	0.12
NPC1	O15118-1.2	K498P	Neutral	0.118
NPC1	O15118-1.2	K498Q	Neutral	0.068
NPC1	O15118-1.2	K498R	Neutral	0.057
NPC1	O15118-1.2	K498S	Neutral	0.115
NPC1	O15118-1.2	K498T	Neutral	0.133
NPC1	O15118-1.2	K498V	Neutral	0.132
NPC1	O15118-1.2	K498W	Neutral	0.135
NPC1	O15118-1.2	K498Y	Neutral	0.125
NPC1	O15118-1.2	K499A	Neutral	0.128
NPC1	O15118-1.2	K499C	Neutral	0.184
NPC1	O15118-1.2	K499D	Neutral	0.153
NPC1	O15118-1.2	K499E	Neutral	0.067
NPC1	O15118-1.2	K499F	Neutral	0.114
NPC1	O15118-1.2	K499G	Neutral	0.211
NPC1	O15118-1.2	K499H	Neutral	0.102
NPC1	O15118-1.2	K499I	Neutral	0.12
NPC1	O15118-1.2	K499L	Neutral	0.087
NPC1	O15118-1.2	K499M	Neutral	0.071
NPC1	O15118-1.2	K499N	Neutral	0.101
NPC1	O15118-1.2	K499P	Neutral	0.1
NPC1	O15118-1.2	K499Q	Neutral	0.057
NPC1	O15118-1.2	K499R	Neutral	0.048
NPC1	O15118-1.2	K499S	Neutral	0.097
NPC1	O15118-1.2	K499T	Neutral	0.113
NPC1	O15118-1.2	K499V	Neutral	0.112
NPC1	O15118-1.2	K499W	Neutral	0.115
NPC1	O15118-1.2	K499Y	Neutral	0.106
NPC1	O15118-1.2	G500A	Neutral	0.39
NPC1	O15118-1.2	G500C	Pathogenic	0.646
NPC1	O15118-1.2	G500D	Neutral	0.482
NPC1	O15118-1.2	G500E	Pathogenic	0.615
NPC1	O15118-1.2	G500F	Pathogenic	0.652
NPC1	O15118-1.2	G500H	Pathogenic	0.666
NPC1	O15118-1.2	G500I	Pathogenic	0.72
NPC1	O15118-1.2	G500K	Pathogenic	0.624
NPC1	O15118-1.2	G500L	Pathogenic	0.726
NPC1	O15118-1.2	G500M	Pathogenic	0.678
NPC1	O15118-1.2	G500N	Neutral	0.408
NPC1	O15118-1.2	G500P	Pathogenic	0.581
NPC1	O15118-1.2	G500Q	Pathogenic	0.654
NPC1	O15118-1.2	G500R	Pathogenic	0.641
NPC1	O15118-1.2	G500S	Neutral	0.42
NPC1	O15118-1.2	G500T	Pathogenic	0.622
NPC1	O15118-1.2	G500V	Pathogenic	0.654
NPC1	O15118-1.2	G500W	Pathogenic	0.564
NPC1	O15118-1.2	G500Y	Pathogenic	0.719
NPC1	O15118-1.2	D501A	Pathogenic	0.704
NPC1	O15118-1.2	D501C	Pathogenic	0.714
NPC1	O15118-1.2	D501E	Neutral	0.402
NPC1	O15118-1.2	D501F	Pathogenic	0.707
NPC1	O15118-1.2	D501G	Pathogenic	0.668
NPC1	O15118-1.2	D501H	Pathogenic	0.636
NPC1	O15118-1.2	D501I	Pathogenic	0.692
NPC1	O15118-1.2	D501K	Pathogenic	0.708
NPC1	O15118-1.2	D501L	Pathogenic	0.774
NPC1	O15118-1.2	D501M	Pathogenic	0.731
NPC1	O15118-1.2	D501N	Neutral	0.474
NPC1	O15118-1.2	D501P	Pathogenic	0.551
NPC1	O15118-1.2	D501Q	Pathogenic	0.566
NPC1	O15118-1.2	D501R	Pathogenic	0.793
NPC1	O15118-1.2	D501S	Pathogenic	0.543
NPC1	O15118-1.2	D501T	Pathogenic	0.59
NPC1	O15118-1.2	D501V	Pathogenic	0.709
NPC1	O15118-1.2	D501W	Pathogenic	0.783
NPC1	O15118-1.2	D501Y	Pathogenic	0.767
NPC1	O15118-1.2	D502A	Neutral	0.415
NPC1	O15118-1.2	D502C	Neutral	0.427
NPC1	O15118-1.2	D502E	Neutral	0.167
NPC1	O15118-1.2	D502F	Neutral	0.419
NPC1	O15118-1.2	D502G	Neutral	0.375
NPC1	O15118-1.2	D502H	Neutral	0.343
NPC1	O15118-1.2	D502I	Neutral	0.402
NPC1	O15118-1.2	D502K	Neutral	0.42
NPC1	O15118-1.2	D502L	Pathogenic	0.505
NPC1	O15118-1.2	D502M	Neutral	0.448
NPC1	O15118-1.2	D502N	Neutral	0.212
NPC1	O15118-1.2	D502P	Neutral	0.268
NPC1	O15118-1.2	D502Q	Neutral	0.28
NPC1	O15118-1.2	D502R	Pathogenic	0.534
NPC1	O15118-1.2	D502S	Neutral	0.262
NPC1	O15118-1.2	D502T	Neutral	0.301
NPC1	O15118-1.2	D502V	Neutral	0.421
NPC1	O15118-1.2	D502W	Pathogenic	0.519
NPC1	O15118-1.2	D502Y	Neutral	0.496
NPC1	O15118-1.2	F503A	Pathogenic	0.759
NPC1	O15118-1.2	F503C	Pathogenic	0.779
NPC1	O15118-1.2	F503D	Pathogenic	0.737
NPC1	O15118-1.2	F503E	Pathogenic	0.724
NPC1	O15118-1.2	F503G	Pathogenic	0.824
NPC1	O15118-1.2	F503H	Pathogenic	0.597
NPC1	O15118-1.2	F503I	Pathogenic	0.627
NPC1	O15118-1.2	F503K	Pathogenic	0.666
NPC1	O15118-1.2	F503L	Pathogenic	0.621
NPC1	O15118-1.2	F503M	Pathogenic	0.584
NPC1	O15118-1.2	F503N	Pathogenic	0.742
NPC1	O15118-1.2	F503P	Pathogenic	0.872
NPC1	O15118-1.2	F503Q	Pathogenic	0.745
NPC1	O15118-1.2	F503R	Pathogenic	0.682
NPC1	O15118-1.2	F503S	Pathogenic	0.73
NPC1	O15118-1.2	F503T	Pathogenic	0.726
NPC1	O15118-1.2	F503V	Pathogenic	0.697
NPC1	O15118-1.2	F503W	Pathogenic	0.522
NPC1	O15118-1.2	F503Y	Neutral	0.281
NPC1	O15118-1.2	F504A	Pathogenic	0.546
NPC1	O15118-1.2	F504C	Pathogenic	0.573
NPC1	O15118-1.2	F504D	Pathogenic	0.517
NPC1	O15118-1.2	F504E	Pathogenic	0.501
NPC1	O15118-1.2	F504G	Pathogenic	0.642
NPC1	O15118-1.2	F504H	Neutral	0.362
NPC1	O15118-1.2	F504I	Neutral	0.391
NPC1	O15118-1.2	F504K	Neutral	0.433
NPC1	O15118-1.2	F504L	Neutral	0.385
NPC1	O15118-1.2	F504M	Neutral	0.349
NPC1	O15118-1.2	F504N	Pathogenic	0.524
NPC1	O15118-1.2	F504P	Pathogenic	0.722
NPC1	O15118-1.2	F504Q	Pathogenic	0.528
NPC1	O15118-1.2	F504R	Neutral	0.451
NPC1	O15118-1.2	F504S	Pathogenic	0.509
NPC1	O15118-1.2	F504T	Pathogenic	0.503
NPC1	O15118-1.2	F504V	Neutral	0.468
NPC1	O15118-1.2	F504W	Neutral	0.294
NPC1	O15118-1.2	F504Y	Neutral	0.13
NPC1	O15118-1.2	V505A	Neutral	0.443
NPC1	O15118-1.2	V505C	Pathogenic	0.566
NPC1	O15118-1.2	V505D	Pathogenic	0.604
NPC1	O15118-1.2	V505E	Pathogenic	0.505
NPC1	O15118-1.2	V505F	Pathogenic	0.555
NPC1	O15118-1.2	V505G	Pathogenic	0.719
NPC1	O15118-1.2	V505H	Pathogenic	0.672
NPC1	O15118-1.2	V505I	Neutral	0.199
NPC1	O15118-1.2	V505K	Pathogenic	0.516
NPC1	O15118-1.2	V505L	Neutral	0.357
NPC1	O15118-1.2	V505M	Neutral	0.393
NPC1	O15118-1.2	V505N	Pathogenic	0.611
NPC1	O15118-1.2	V505P	Pathogenic	0.632
NPC1	O15118-1.2	V505Q	Pathogenic	0.548
NPC1	O15118-1.2	V505R	Pathogenic	0.628
NPC1	O15118-1.2	V505S	Pathogenic	0.596
NPC1	O15118-1.2	V505T	Neutral	0.4
NPC1	O15118-1.2	V505W	Pathogenic	0.732
NPC1	O15118-1.2	V505Y	Pathogenic	0.589
NPC1	O15118-1.2	Y506A	Pathogenic	0.614
NPC1	O15118-1.2	Y506C	Pathogenic	0.636
NPC1	O15118-1.2	Y506D	Pathogenic	0.586
NPC1	O15118-1.2	Y506E	Neutral	0.474
NPC1	O15118-1.2	Y506F	Neutral	0.126
NPC1	O15118-1.2	Y506G	Pathogenic	0.703
NPC1	O15118-1.2	Y506H	Neutral	0.191
NPC1	O15118-1.2	Y506I	Neutral	0.418
NPC1	O15118-1.2	Y506K	Neutral	0.406
NPC1	O15118-1.2	Y506L	Neutral	0.426
NPC1	O15118-1.2	Y506M	Neutral	0.465
NPC1	O15118-1.2	Y506N	Neutral	0.497
NPC1	O15118-1.2	Y506P	Pathogenic	0.7
NPC1	O15118-1.2	Y506Q	Neutral	0.406
NPC1	O15118-1.2	Y506R	Neutral	0.407
NPC1	O15118-1.2	Y506S	Pathogenic	0.578
NPC1	O15118-1.2	Y506T	Pathogenic	0.572
NPC1	O15118-1.2	Y506V	Neutral	0.495
NPC1	O15118-1.2	Y506W	Neutral	0.167
NPC1	O15118-1.2	A507C	Neutral	0.466
NPC1	O15118-1.2	A507D	Pathogenic	0.629
NPC1	O15118-1.2	A507E	Pathogenic	0.574
NPC1	O15118-1.2	A507F	Pathogenic	0.66
NPC1	O15118-1.2	A507G	Neutral	0.496
NPC1	O15118-1.2	A507H	Pathogenic	0.73
NPC1	O15118-1.2	A507I	Pathogenic	0.551
NPC1	O15118-1.2	A507K	Pathogenic	0.583
NPC1	O15118-1.2	A507L	Pathogenic	0.559
NPC1	O15118-1.2	A507M	Pathogenic	0.597
NPC1	O15118-1.2	A507N	Pathogenic	0.649
NPC1	O15118-1.2	A507P	Pathogenic	0.589
NPC1	O15118-1.2	A507Q	Pathogenic	0.614
NPC1	O15118-1.2	A507R	Pathogenic	0.601
NPC1	O15118-1.2	A507S	Neutral	0.379
NPC1	O15118-1.2	A507T	Pathogenic	0.528
NPC1	O15118-1.2	A507V	Neutral	0.475
NPC1	O15118-1.2	A507W	Pathogenic	0.743
NPC1	O15118-1.2	A507Y	Pathogenic	0.726
NPC1	O15118-1.2	D508A	Pathogenic	0.818
NPC1	O15118-1.2	D508C	Pathogenic	0.825
NPC1	O15118-1.2	D508E	Pathogenic	0.559
NPC1	O15118-1.2	D508F	Pathogenic	0.82
NPC1	O15118-1.2	D508G	Pathogenic	0.791
NPC1	O15118-1.2	D508H	Pathogenic	0.767
NPC1	O15118-1.2	D508I	Pathogenic	0.809
NPC1	O15118-1.2	D508K	Pathogenic	0.821
NPC1	O15118-1.2	D508L	Pathogenic	0.866
NPC1	O15118-1.2	D508M	Pathogenic	0.837
NPC1	O15118-1.2	D508N	Pathogenic	0.63
NPC1	O15118-1.2	D508P	Pathogenic	0.699
NPC1	O15118-1.2	D508Q	Pathogenic	0.711
NPC1	O15118-1.2	D508R	Pathogenic	0.879
NPC1	O15118-1.2	D508S	Pathogenic	0.692
NPC1	O15118-1.2	D508T	Pathogenic	0.731
NPC1	O15118-1.2	D508V	Pathogenic	0.821
NPC1	O15118-1.2	D508W	Pathogenic	0.872
NPC1	O15118-1.2	D508Y	Pathogenic	0.862
NPC1	O15118-1.2	Y509A	Pathogenic	0.959
NPC1	O15118-1.2	Y509C	Pathogenic	0.963
NPC1	O15118-1.2	Y509D	Pathogenic	0.955
NPC1	O15118-1.2	Y509E	Pathogenic	0.93
NPC1	O15118-1.2	Y509F	Pathogenic	0.682
NPC1	O15118-1.2	Y509G	Pathogenic	0.972
NPC1	O15118-1.2	Y509H	Pathogenic	0.777
NPC1	O15118-1.2	Y509I	Pathogenic	0.914
NPC1	O15118-1.2	Y509K	Pathogenic	0.91
NPC1	O15118-1.2	Y509L	Pathogenic	0.917
NPC1	O15118-1.2	Y509M	Pathogenic	0.928
NPC1	O15118-1.2	Y509N	Pathogenic	0.936
NPC1	O15118-1.2	Y509P	Pathogenic	0.972
NPC1	O15118-1.2	Y509Q	Pathogenic	0.91
NPC1	O15118-1.2	Y509R	Pathogenic	0.91
NPC1	O15118-1.2	Y509S	Pathogenic	0.953
NPC1	O15118-1.2	Y509T	Pathogenic	0.952
NPC1	O15118-1.2	Y509V	Pathogenic	0.936
NPC1	O15118-1.2	Y509W	Pathogenic	0.749
NPC1	O15118-1.2	H510A	Pathogenic	0.912
NPC1	O15118-1.2	H510C	Pathogenic	0.915
NPC1	O15118-1.2	H510D	Pathogenic	0.826
NPC1	O15118-1.2	H510E	Pathogenic	0.752
NPC1	O15118-1.2	H510F	Pathogenic	0.777
NPC1	O15118-1.2	H510G	Pathogenic	0.921
NPC1	O15118-1.2	H510I	Pathogenic	0.875
NPC1	O15118-1.2	H510K	Pathogenic	0.806
NPC1	O15118-1.2	H510L	Pathogenic	0.879
NPC1	O15118-1.2	H510M	Pathogenic	0.852
NPC1	O15118-1.2	H510N	Pathogenic	0.693
NPC1	O15118-1.2	H510P	Pathogenic	0.887
NPC1	O15118-1.2	H510Q	Pathogenic	0.772
NPC1	O15118-1.2	H510R	Pathogenic	0.753
NPC1	O15118-1.2	H510S	Pathogenic	0.871
NPC1	O15118-1.2	H510T	Pathogenic	0.9
NPC1	O15118-1.2	H510V	Pathogenic	0.899
NPC1	O15118-1.2	H510W	Pathogenic	0.839
NPC1	O15118-1.2	H510Y	Pathogenic	0.599
NPC1	O15118-1.2	T511A	Pathogenic	0.739
NPC1	O15118-1.2	T511C	Pathogenic	0.748
NPC1	O15118-1.2	T511D	Pathogenic	0.723
NPC1	O15118-1.2	T511E	Pathogenic	0.748
NPC1	O15118-1.2	T511F	Pathogenic	0.805
NPC1	O15118-1.2	T511G	Pathogenic	0.865
NPC1	O15118-1.2	T511H	Pathogenic	0.856
NPC1	O15118-1.2	T511I	Pathogenic	0.724
NPC1	O15118-1.2	T511K	Pathogenic	0.756
NPC1	O15118-1.2	T511L	Pathogenic	0.73
NPC1	O15118-1.2	T511M	Pathogenic	0.76
NPC1	O15118-1.2	T511N	Pathogenic	0.654
NPC1	O15118-1.2	T511P	Pathogenic	0.76
NPC1	O15118-1.2	T511Q	Pathogenic	0.779
NPC1	O15118-1.2	T511R	Pathogenic	0.769
NPC1	O15118-1.2	T511S	Pathogenic	0.632
NPC1	O15118-1.2	T511V	Pathogenic	0.658
NPC1	O15118-1.2	T511W	Pathogenic	0.808
NPC1	O15118-1.2	T511Y	Pathogenic	0.85
NPC1	O15118-1.2	H512A	Pathogenic	0.956
NPC1	O15118-1.2	H512C	Pathogenic	0.958
NPC1	O15118-1.2	H512D	Pathogenic	0.909
NPC1	O15118-1.2	H512E	Pathogenic	0.865
NPC1	O15118-1.2	H512F	Pathogenic	0.88
NPC1	O15118-1.2	H512G	Pathogenic	0.961
NPC1	O15118-1.2	H512I	Pathogenic	0.937
NPC1	O15118-1.2	H512K	Pathogenic	0.898
NPC1	O15118-1.2	H512L	Pathogenic	0.939
NPC1	O15118-1.2	H512M	Pathogenic	0.924
NPC1	O15118-1.2	H512N	Pathogenic	0.827
NPC1	O15118-1.2	H512P	Pathogenic	0.943
NPC1	O15118-1.2	H512Q	Pathogenic	0.877
NPC1	O15118-1.2	H512R	Pathogenic	0.865
NPC1	O15118-1.2	H512S	Pathogenic	0.935
NPC1	O15118-1.2	H512T	Pathogenic	0.95
NPC1	O15118-1.2	H512V	Pathogenic	0.949
NPC1	O15118-1.2	H512W	Pathogenic	0.917
NPC1	O15118-1.2	H512Y	Pathogenic	0.759
NPC1	O15118-1.2	F513A	Pathogenic	0.844
NPC1	O15118-1.2	F513C	Pathogenic	0.858
NPC1	O15118-1.2	F513D	Pathogenic	0.828
NPC1	O15118-1.2	F513E	Pathogenic	0.818
NPC1	O15118-1.2	F513G	Pathogenic	0.889
NPC1	O15118-1.2	F513H	Pathogenic	0.718
NPC1	O15118-1.2	F513I	Pathogenic	0.742
NPC1	O15118-1.2	F513K	Pathogenic	0.774
NPC1	O15118-1.2	F513L	Pathogenic	0.738
NPC1	O15118-1.2	F513M	Pathogenic	0.706
NPC1	O15118-1.2	F513N	Pathogenic	0.831
NPC1	O15118-1.2	F513P	Pathogenic	0.921
NPC1	O15118-1.2	F513Q	Pathogenic	0.834
NPC1	O15118-1.2	F513R	Pathogenic	0.786
NPC1	O15118-1.2	F513S	Pathogenic	0.823
NPC1	O15118-1.2	F513T	Pathogenic	0.819
NPC1	O15118-1.2	F513V	Pathogenic	0.798
NPC1	O15118-1.2	F513W	Pathogenic	0.652
NPC1	O15118-1.2	F513Y	Neutral	0.401
NPC1	O15118-1.2	L514A	Neutral	0.44
NPC1	O15118-1.2	L514C	Neutral	0.467
NPC1	O15118-1.2	L514D	Pathogenic	0.602
NPC1	O15118-1.2	L514E	Neutral	0.491
NPC1	O15118-1.2	L514F	Neutral	0.384
NPC1	O15118-1.2	L514G	Pathogenic	0.717
NPC1	O15118-1.2	L514H	Pathogenic	0.541
NPC1	O15118-1.2	L514I	Neutral	0.212
NPC1	O15118-1.2	L514K	Neutral	0.363
NPC1	O15118-1.2	L514M	Neutral	0.192
NPC1	O15118-1.2	L514N	Pathogenic	0.513
NPC1	O15118-1.2	L514P	Pathogenic	0.629
NPC1	O15118-1.2	L514Q	Neutral	0.422
NPC1	O15118-1.2	L514R	Neutral	0.38
NPC1	O15118-1.2	L514S	Neutral	0.499
NPC1	O15118-1.2	L514T	Neutral	0.398
NPC1	O15118-1.2	L514V	Neutral	0.281
NPC1	O15118-1.2	L514W	Pathogenic	0.578
NPC1	O15118-1.2	L514Y	Neutral	0.434
NPC1	O15118-1.2	Y515A	Pathogenic	0.751
NPC1	O15118-1.2	Y515C	Pathogenic	0.769
NPC1	O15118-1.2	Y515D	Pathogenic	0.729
NPC1	O15118-1.2	Y515E	Pathogenic	0.631
NPC1	O15118-1.2	Y515F	Neutral	0.215
NPC1	O15118-1.2	Y515G	Pathogenic	0.818
NPC1	O15118-1.2	Y515H	Neutral	0.309
NPC1	O15118-1.2	Y515I	Pathogenic	0.577
NPC1	O15118-1.2	Y515K	Pathogenic	0.566
NPC1	O15118-1.2	Y515L	Pathogenic	0.586
NPC1	O15118-1.2	Y515M	Pathogenic	0.623
NPC1	O15118-1.2	Y515N	Pathogenic	0.652
NPC1	O15118-1.2	Y515P	Pathogenic	0.816
NPC1	O15118-1.2	Y515Q	Pathogenic	0.565
NPC1	O15118-1.2	Y515R	Pathogenic	0.566
NPC1	O15118-1.2	Y515S	Pathogenic	0.722
NPC1	O15118-1.2	Y515T	Pathogenic	0.717
NPC1	O15118-1.2	Y515V	Pathogenic	0.651
NPC1	O15118-1.2	Y515W	Neutral	0.276
NPC1	O15118-1.2	C516A	Pathogenic	0.953
NPC1	O15118-1.2	C516D	Pathogenic	0.976
NPC1	O15118-1.2	C516E	Pathogenic	0.986
NPC1	O15118-1.2	C516F	Pathogenic	0.98
NPC1	O15118-1.2	C516G	Pathogenic	0.985
NPC1	O15118-1.2	C516H	Pathogenic	0.985
NPC1	O15118-1.2	C516I	Pathogenic	0.969
NPC1	O15118-1.2	C516K	Pathogenic	0.98
NPC1	O15118-1.2	C516L	Pathogenic	0.97
NPC1	O15118-1.2	C516M	Pathogenic	0.975
NPC1	O15118-1.2	C516N	Pathogenic	0.978
NPC1	O15118-1.2	C516P	Pathogenic	0.985
NPC1	O15118-1.2	C516Q	Pathogenic	0.983
NPC1	O15118-1.2	C516R	Pathogenic	0.982
NPC1	O15118-1.2	C516S	Pathogenic	0.962
NPC1	O15118-1.2	C516T	Pathogenic	0.964
NPC1	O15118-1.2	C516V	Pathogenic	0.972
NPC1	O15118-1.2	C516W	Pathogenic	0.981
NPC1	O15118-1.2	C516Y	Pathogenic	0.985
NPC1	O15118-1.2	V517A	Neutral	0.388
NPC1	O15118-1.2	V517C	Pathogenic	0.51
NPC1	O15118-1.2	V517D	Pathogenic	0.55
NPC1	O15118-1.2	V517E	Neutral	0.45
NPC1	O15118-1.2	V517F	Neutral	0.499
NPC1	O15118-1.2	V517G	Pathogenic	0.672
NPC1	O15118-1.2	V517H	Pathogenic	0.621
NPC1	O15118-1.2	V517I	Neutral	0.165
NPC1	O15118-1.2	V517K	Neutral	0.46
NPC1	O15118-1.2	V517L	Neutral	0.307
NPC1	O15118-1.2	V517M	Neutral	0.341
NPC1	O15118-1.2	V517N	Pathogenic	0.556
NPC1	O15118-1.2	V517P	Pathogenic	0.578
NPC1	O15118-1.2	V517Q	Neutral	0.492
NPC1	O15118-1.2	V517R	Pathogenic	0.574
NPC1	O15118-1.2	V517S	Pathogenic	0.542
NPC1	O15118-1.2	V517T	Neutral	0.348
NPC1	O15118-1.2	V517W	Pathogenic	0.686
NPC1	O15118-1.2	V517Y	Pathogenic	0.534
NPC1	O15118-1.2	R518A	Pathogenic	0.531
NPC1	O15118-1.2	R518C	Pathogenic	0.635
NPC1	O15118-1.2	R518D	Pathogenic	0.673
NPC1	O15118-1.2	R518E	Neutral	0.449
NPC1	O15118-1.2	R518F	Neutral	0.498
NPC1	O15118-1.2	R518G	Pathogenic	0.674
NPC1	O15118-1.2	R518H	Neutral	0.374
NPC1	O15118-1.2	R518I	Pathogenic	0.513
NPC1	O15118-1.2	R518K	Neutral	0.266
NPC1	O15118-1.2	R518L	Neutral	0.426
NPC1	O15118-1.2	R518M	Neutral	0.371
NPC1	O15118-1.2	R518N	Neutral	0.466
NPC1	O15118-1.2	R518P	Pathogenic	0.558
NPC1	O15118-1.2	R518Q	Neutral	0.319
NPC1	O15118-1.2	R518S	Pathogenic	0.55
NPC1	O15118-1.2	R518T	Neutral	0.496
NPC1	O15118-1.2	R518V	Pathogenic	0.59
NPC1	O15118-1.2	R518W	Neutral	0.462
NPC1	O15118-1.2	R518Y	Neutral	0.461
NPC1	O15118-1.2	A519C	Pathogenic	0.539
NPC1	O15118-1.2	A519D	Pathogenic	0.695
NPC1	O15118-1.2	A519E	Pathogenic	0.644
NPC1	O15118-1.2	A519F	Pathogenic	0.723
NPC1	O15118-1.2	A519G	Pathogenic	0.569
NPC1	O15118-1.2	A519H	Pathogenic	0.784
NPC1	O15118-1.2	A519I	Pathogenic	0.623
NPC1	O15118-1.2	A519K	Pathogenic	0.653
NPC1	O15118-1.2	A519L	Pathogenic	0.631
NPC1	O15118-1.2	A519M	Pathogenic	0.666
NPC1	O15118-1.2	A519N	Pathogenic	0.713
NPC1	O15118-1.2	A519P	Pathogenic	0.658
NPC1	O15118-1.2	A519Q	Pathogenic	0.682
NPC1	O15118-1.2	A519R	Pathogenic	0.67
NPC1	O15118-1.2	A519S	Neutral	0.451
NPC1	O15118-1.2	A519T	Pathogenic	0.6
NPC1	O15118-1.2	A519V	Pathogenic	0.549
NPC1	O15118-1.2	A519W	Pathogenic	0.796
NPC1	O15118-1.2	A519Y	Pathogenic	0.781
NPC1	O15118-1.2	P520A	Pathogenic	0.905
NPC1	O15118-1.2	P520C	Pathogenic	0.951
NPC1	O15118-1.2	P520D	Pathogenic	0.854
NPC1	O15118-1.2	P520E	Pathogenic	0.872
NPC1	O15118-1.2	P520F	Pathogenic	0.965
NPC1	O15118-1.2	P520G	Pathogenic	0.934
NPC1	O15118-1.2	P520H	Pathogenic	0.932
NPC1	O15118-1.2	P520I	Pathogenic	0.946
NPC1	O15118-1.2	P520K	Pathogenic	0.877
NPC1	O15118-1.2	P520L	Pathogenic	0.948
NPC1	O15118-1.2	P520M	Pathogenic	0.936
NPC1	O15118-1.2	P520N	Pathogenic	0.904
NPC1	O15118-1.2	P520Q	Pathogenic	0.89
NPC1	O15118-1.2	P520R	Pathogenic	0.918
NPC1	O15118-1.2	P520S	Pathogenic	0.892
NPC1	O15118-1.2	P520T	Pathogenic	0.893
NPC1	O15118-1.2	P520V	Pathogenic	0.929
NPC1	O15118-1.2	P520W	Pathogenic	0.966
NPC1	O15118-1.2	P520Y	Pathogenic	0.963
NPC1	O15118-1.2	A521C	Neutral	0.464
NPC1	O15118-1.2	A521D	Pathogenic	0.628
NPC1	O15118-1.2	A521E	Pathogenic	0.573
NPC1	O15118-1.2	A521F	Pathogenic	0.659
NPC1	O15118-1.2	A521G	Neutral	0.495
NPC1	O15118-1.2	A521H	Pathogenic	0.729
NPC1	O15118-1.2	A521I	Pathogenic	0.55
NPC1	O15118-1.2	A521K	Pathogenic	0.582
NPC1	O15118-1.2	A521L	Pathogenic	0.558
NPC1	O15118-1.2	A521M	Pathogenic	0.596
NPC1	O15118-1.2	A521N	Pathogenic	0.648
NPC1	O15118-1.2	A521P	Pathogenic	0.588
NPC1	O15118-1.2	A521Q	Pathogenic	0.613
NPC1	O15118-1.2	A521R	Pathogenic	0.6
NPC1	O15118-1.2	A521S	Neutral	0.378
NPC1	O15118-1.2	A521T	Pathogenic	0.527
NPC1	O15118-1.2	A521V	Neutral	0.474
NPC1	O15118-1.2	A521W	Pathogenic	0.743
NPC1	O15118-1.2	A521Y	Pathogenic	0.725
NPC1	O15118-1.2	S522A	Pathogenic	0.623
NPC1	O15118-1.2	S522C	Pathogenic	0.749
NPC1	O15118-1.2	S522D	Pathogenic	0.696
NPC1	O15118-1.2	S522E	Pathogenic	0.728
NPC1	O15118-1.2	S522F	Pathogenic	0.818
NPC1	O15118-1.2	S522G	Pathogenic	0.751
NPC1	O15118-1.2	S522H	Pathogenic	0.827
NPC1	O15118-1.2	S522I	Pathogenic	0.808
NPC1	O15118-1.2	S522K	Pathogenic	0.736
NPC1	O15118-1.2	S522L	Pathogenic	0.813
NPC1	O15118-1.2	S522M	Pathogenic	0.775
NPC1	O15118-1.2	S522N	Pathogenic	0.63
NPC1	O15118-1.2	S522P	Pathogenic	0.769
NPC1	O15118-1.2	S522Q	Pathogenic	0.76
NPC1	O15118-1.2	S522R	Pathogenic	0.815
NPC1	O15118-1.2	S522T	Pathogenic	0.646
NPC1	O15118-1.2	S522V	Pathogenic	0.82
NPC1	O15118-1.2	S522W	Pathogenic	0.871
NPC1	O15118-1.2	S522Y	Pathogenic	0.86
NPC1	O15118-1.2	L523A	Pathogenic	0.51
NPC1	O15118-1.2	L523C	Pathogenic	0.538
NPC1	O15118-1.2	L523D	Pathogenic	0.667
NPC1	O15118-1.2	L523E	Pathogenic	0.561
NPC1	O15118-1.2	L523F	Neutral	0.453
NPC1	O15118-1.2	L523G	Pathogenic	0.771
NPC1	O15118-1.2	L523H	Pathogenic	0.61
NPC1	O15118-1.2	L523I	Neutral	0.263
NPC1	O15118-1.2	L523K	Neutral	0.43
NPC1	O15118-1.2	L523M	Neutral	0.24
NPC1	O15118-1.2	L523N	Pathogenic	0.583
NPC1	O15118-1.2	L523P	Pathogenic	0.692
NPC1	O15118-1.2	L523Q	Neutral	0.492
NPC1	O15118-1.2	L523R	Neutral	0.448
NPC1	O15118-1.2	L523S	Pathogenic	0.569
NPC1	O15118-1.2	L523T	Neutral	0.467
NPC1	O15118-1.2	L523V	Neutral	0.341
NPC1	O15118-1.2	L523W	Pathogenic	0.645
NPC1	O15118-1.2	L523Y	Pathogenic	0.504
NPC1	O15118-1.2	N524A	Neutral	0.291
NPC1	O15118-1.2	N524C	Neutral	0.301
NPC1	O15118-1.2	N524D	Neutral	0.125
NPC1	O15118-1.2	N524E	Neutral	0.187
NPC1	O15118-1.2	N524F	Neutral	0.282
NPC1	O15118-1.2	N524G	Neutral	0.191
NPC1	O15118-1.2	N524H	Neutral	0.116
NPC1	O15118-1.2	N524I	Neutral	0.267
NPC1	O15118-1.2	N524K	Neutral	0.193
NPC1	O15118-1.2	N524L	Neutral	0.274
NPC1	O15118-1.2	N524M	Neutral	0.231
NPC1	O15118-1.2	N524P	Neutral	0.238
NPC1	O15118-1.2	N524Q	Neutral	0.175
NPC1	O15118-1.2	N524R	Neutral	0.205
NPC1	O15118-1.2	N524S	Neutral	0.122
NPC1	O15118-1.2	N524T	Neutral	0.142
NPC1	O15118-1.2	N524V	Neutral	0.283
NPC1	O15118-1.2	N524W	Neutral	0.369
NPC1	O15118-1.2	N524Y	Neutral	0.267
NPC1	O15118-1.2	D525A	Pathogenic	0.878
NPC1	O15118-1.2	D525C	Pathogenic	0.883
NPC1	O15118-1.2	D525E	Pathogenic	0.67
NPC1	O15118-1.2	D525F	Pathogenic	0.88
NPC1	O15118-1.2	D525G	Pathogenic	0.859
NPC1	O15118-1.2	D525H	Pathogenic	0.841
NPC1	O15118-1.2	D525I	Pathogenic	0.872
NPC1	O15118-1.2	D525K	Pathogenic	0.88
NPC1	O15118-1.2	D525L	Pathogenic	0.912
NPC1	O15118-1.2	D525M	Pathogenic	0.892
NPC1	O15118-1.2	D525N	Pathogenic	0.732
NPC1	O15118-1.2	D525P	Pathogenic	0.788
NPC1	O15118-1.2	D525Q	Pathogenic	0.798
NPC1	O15118-1.2	D525R	Pathogenic	0.921
NPC1	O15118-1.2	D525S	Pathogenic	0.782
NPC1	O15118-1.2	D525T	Pathogenic	0.813
NPC1	O15118-1.2	D525V	Pathogenic	0.88
NPC1	O15118-1.2	D525W	Pathogenic	0.916
NPC1	O15118-1.2	D525Y	Pathogenic	0.909
NPC1	O15118-1.2	T526A	Pathogenic	0.567
NPC1	O15118-1.2	T526C	Pathogenic	0.578
NPC1	O15118-1.2	T526D	Pathogenic	0.546
NPC1	O15118-1.2	T526E	Pathogenic	0.578
NPC1	O15118-1.2	T526F	Pathogenic	0.656
NPC1	O15118-1.2	T526G	Pathogenic	0.748
NPC1	O15118-1.2	T526H	Pathogenic	0.733
NPC1	O15118-1.2	T526I	Pathogenic	0.547
NPC1	O15118-1.2	T526K	Pathogenic	0.588
NPC1	O15118-1.2	T526L	Pathogenic	0.555
NPC1	O15118-1.2	T526M	Pathogenic	0.593
NPC1	O15118-1.2	T526N	Neutral	0.466
NPC1	O15118-1.2	T526P	Pathogenic	0.594
NPC1	O15118-1.2	T526Q	Pathogenic	0.619
NPC1	O15118-1.2	T526R	Pathogenic	0.605
NPC1	O15118-1.2	T526S	Neutral	0.442
NPC1	O15118-1.2	T526V	Neutral	0.471
NPC1	O15118-1.2	T526W	Pathogenic	0.66
NPC1	O15118-1.2	T526Y	Pathogenic	0.723
NPC1	O15118-1.2	S527A	Neutral	0.371
NPC1	O15118-1.2	S527C	Pathogenic	0.515
NPC1	O15118-1.2	S527D	Neutral	0.45
NPC1	O15118-1.2	S527E	Neutral	0.489
NPC1	O15118-1.2	S527F	Pathogenic	0.617
NPC1	O15118-1.2	S527G	Pathogenic	0.519
NPC1	O15118-1.2	S527H	Pathogenic	0.631
NPC1	O15118-1.2	S527I	Pathogenic	0.6
NPC1	O15118-1.2	S527K	Neutral	0.499
NPC1	O15118-1.2	S527L	Pathogenic	0.608
NPC1	O15118-1.2	S527M	Pathogenic	0.552
NPC1	O15118-1.2	S527N	Neutral	0.378
NPC1	O15118-1.2	S527P	Pathogenic	0.543
NPC1	O15118-1.2	S527Q	Pathogenic	0.531
NPC1	O15118-1.2	S527R	Pathogenic	0.612
NPC1	O15118-1.2	S527T	Neutral	0.395
NPC1	O15118-1.2	S527V	Pathogenic	0.619
NPC1	O15118-1.2	S527W	Pathogenic	0.706
NPC1	O15118-1.2	S527Y	Pathogenic	0.687
NPC1	O15118-1.2	L528A	Neutral	0.236
NPC1	O15118-1.2	L528C	Neutral	0.256
NPC1	O15118-1.2	L528D	Neutral	0.373
NPC1	O15118-1.2	L528E	Neutral	0.275
NPC1	O15118-1.2	L528F	Neutral	0.197
NPC1	O15118-1.2	L528G	Neutral	0.499
NPC1	O15118-1.2	L528H	Neutral	0.316
NPC1	O15118-1.2	L528I	Neutral	0.095
NPC1	O15118-1.2	L528K	Neutral	0.183
NPC1	O15118-1.2	L528M	Neutral	0.085
NPC1	O15118-1.2	L528N	Neutral	0.293
NPC1	O15118-1.2	L528P	Neutral	0.4
NPC1	O15118-1.2	L528Q	Neutral	0.223
NPC1	O15118-1.2	L528R	Neutral	0.194
NPC1	O15118-1.2	L528S	Neutral	0.281
NPC1	O15118-1.2	L528T	Neutral	0.206
NPC1	O15118-1.2	L528V	Neutral	0.133
NPC1	O15118-1.2	L528W	Neutral	0.35
NPC1	O15118-1.2	L528Y	Neutral	0.231
NPC1	O15118-1.2	L529A	Pathogenic	0.714
NPC1	O15118-1.2	L529C	Pathogenic	0.736
NPC1	O15118-1.2	L529D	Pathogenic	0.828
NPC1	O15118-1.2	L529E	Pathogenic	0.754
NPC1	O15118-1.2	L529F	Pathogenic	0.665
NPC1	O15118-1.2	L529G	Pathogenic	0.89
NPC1	O15118-1.2	L529H	Pathogenic	0.789
NPC1	O15118-1.2	L529I	Neutral	0.461
NPC1	O15118-1.2	L529K	Pathogenic	0.644
NPC1	O15118-1.2	L529M	Neutral	0.431
NPC1	O15118-1.2	L529N	Pathogenic	0.77
NPC1	O15118-1.2	L529P	Pathogenic	0.844
NPC1	O15118-1.2	L529Q	Pathogenic	0.699
NPC1	O15118-1.2	L529R	Pathogenic	0.661
NPC1	O15118-1.2	L529S	Pathogenic	0.76
NPC1	O15118-1.2	L529T	Pathogenic	0.678
NPC1	O15118-1.2	L529V	Pathogenic	0.554
NPC1	O15118-1.2	L529W	Pathogenic	0.814
NPC1	O15118-1.2	L529Y	Pathogenic	0.709
NPC1	O15118-1.2	H530A	Pathogenic	0.778
NPC1	O15118-1.2	H530C	Pathogenic	0.786
NPC1	O15118-1.2	H530D	Pathogenic	0.618
NPC1	O15118-1.2	H530E	Pathogenic	0.507
NPC1	O15118-1.2	H530F	Pathogenic	0.542
NPC1	O15118-1.2	H530G	Pathogenic	0.799
NPC1	O15118-1.2	H530I	Pathogenic	0.705
NPC1	O15118-1.2	H530K	Pathogenic	0.586
NPC1	O15118-1.2	H530L	Pathogenic	0.712
NPC1	O15118-1.2	H530M	Pathogenic	0.662
NPC1	O15118-1.2	H530N	Neutral	0.434
NPC1	O15118-1.2	H530P	Pathogenic	0.727
NPC1	O15118-1.2	H530Q	Pathogenic	0.535
NPC1	O15118-1.2	H530R	Pathogenic	0.509
NPC1	O15118-1.2	H530S	Pathogenic	0.697
NPC1	O15118-1.2	H530T	Pathogenic	0.753
NPC1	O15118-1.2	H530V	Pathogenic	0.752
NPC1	O15118-1.2	H530W	Pathogenic	0.639
NPC1	O15118-1.2	H530Y	Neutral	0.337
NPC1	O15118-1.2	D531A	Neutral	0.44
NPC1	O15118-1.2	D531C	Neutral	0.451
NPC1	O15118-1.2	D531E	Neutral	0.181
NPC1	O15118-1.2	D531F	Neutral	0.444
NPC1	O15118-1.2	D531G	Neutral	0.399
NPC1	O15118-1.2	D531H	Neutral	0.366
NPC1	O15118-1.2	D531I	Neutral	0.426
NPC1	O15118-1.2	D531K	Neutral	0.445
NPC1	O15118-1.2	D531L	Pathogenic	0.53
NPC1	O15118-1.2	D531M	Neutral	0.473
NPC1	O15118-1.2	D531N	Neutral	0.229
NPC1	O15118-1.2	D531P	Neutral	0.288
NPC1	O15118-1.2	D531Q	Neutral	0.301
NPC1	O15118-1.2	D531R	Pathogenic	0.559
NPC1	O15118-1.2	D531S	Neutral	0.282
NPC1	O15118-1.2	D531T	Neutral	0.322
NPC1	O15118-1.2	D531V	Neutral	0.446
NPC1	O15118-1.2	D531W	Pathogenic	0.544
NPC1	O15118-1.2	D531Y	Pathogenic	0.521
NPC1	O15118-1.2	P532A	Pathogenic	0.77
NPC1	O15118-1.2	P532C	Pathogenic	0.871
NPC1	O15118-1.2	P532D	Pathogenic	0.672
NPC1	O15118-1.2	P532E	Pathogenic	0.705
NPC1	O15118-1.2	P532F	Pathogenic	0.907
NPC1	O15118-1.2	P532G	Pathogenic	0.833
NPC1	O15118-1.2	P532H	Pathogenic	0.827
NPC1	O15118-1.2	P532I	Pathogenic	0.861
NPC1	O15118-1.2	P532K	Pathogenic	0.713
NPC1	O15118-1.2	P532L	Pathogenic	0.865
NPC1	O15118-1.2	P532M	Pathogenic	0.836
NPC1	O15118-1.2	P532N	Pathogenic	0.766
NPC1	O15118-1.2	P532Q	Pathogenic	0.738
NPC1	O15118-1.2	P532R	Pathogenic	0.797
NPC1	O15118-1.2	P532S	Pathogenic	0.742
NPC1	O15118-1.2	P532T	Pathogenic	0.745
NPC1	O15118-1.2	P532V	Pathogenic	0.82
NPC1	O15118-1.2	P532W	Pathogenic	0.908
NPC1	O15118-1.2	P532Y	Pathogenic	0.901
NPC1	O15118-1.2	C533A	Pathogenic	0.946
NPC1	O15118-1.2	C533D	Pathogenic	0.973
NPC1	O15118-1.2	C533E	Pathogenic	0.984
NPC1	O15118-1.2	C533F	Pathogenic	0.978
NPC1	O15118-1.2	C533G	Pathogenic	0.983
NPC1	O15118-1.2	C533H	Pathogenic	0.983
NPC1	O15118-1.2	C533I	Pathogenic	0.965
NPC1	O15118-1.2	C533K	Pathogenic	0.978
NPC1	O15118-1.2	C533L	Pathogenic	0.966
NPC1	O15118-1.2	C533M	Pathogenic	0.971
NPC1	O15118-1.2	C533N	Pathogenic	0.975
NPC1	O15118-1.2	C533P	Pathogenic	0.983
NPC1	O15118-1.2	C533Q	Pathogenic	0.98
NPC1	O15118-1.2	C533R	Pathogenic	0.979
NPC1	O15118-1.2	C533S	Pathogenic	0.957
NPC1	O15118-1.2	C533T	Pathogenic	0.96
NPC1	O15118-1.2	C533V	Pathogenic	0.968
NPC1	O15118-1.2	C533W	Pathogenic	0.978
NPC1	O15118-1.2	C533Y	Pathogenic	0.983
NPC1	O15118-1.2	L534A	Pathogenic	0.858
NPC1	O15118-1.2	L534C	Pathogenic	0.871
NPC1	O15118-1.2	L534D	Pathogenic	0.921
NPC1	O15118-1.2	L534E	Pathogenic	0.881
NPC1	O15118-1.2	L534F	Pathogenic	0.827
NPC1	O15118-1.2	L534G	Pathogenic	0.951
NPC1	O15118-1.2	L534H	Pathogenic	0.9
NPC1	O15118-1.2	L534I	Pathogenic	0.673
NPC1	O15118-1.2	L534K	Pathogenic	0.814
NPC1	O15118-1.2	L534M	Pathogenic	0.646
NPC1	O15118-1.2	L534N	Pathogenic	0.89
NPC1	O15118-1.2	L534P	Pathogenic	0.929
NPC1	O15118-1.2	L534Q	Pathogenic	0.849
NPC1	O15118-1.2	L534R	Pathogenic	0.825
NPC1	O15118-1.2	L534S	Pathogenic	0.884
NPC1	O15118-1.2	L534T	Pathogenic	0.835
NPC1	O15118-1.2	L534V	Pathogenic	0.75
NPC1	O15118-1.2	L534W	Pathogenic	0.913
NPC1	O15118-1.2	L534Y	Pathogenic	0.855
NPC1	O15118-1.2	G535A	Pathogenic	0.757
NPC1	O15118-1.2	G535C	Pathogenic	0.899
NPC1	O15118-1.2	G535D	Pathogenic	0.819
NPC1	O15118-1.2	G535E	Pathogenic	0.886
NPC1	O15118-1.2	G535F	Pathogenic	0.901
NPC1	O15118-1.2	G535H	Pathogenic	0.907
NPC1	O15118-1.2	G535I	Pathogenic	0.926
NPC1	O15118-1.2	G535K	Pathogenic	0.89
NPC1	O15118-1.2	G535L	Pathogenic	0.928
NPC1	O15118-1.2	G535M	Pathogenic	0.911
NPC1	O15118-1.2	G535N	Pathogenic	0.771
NPC1	O15118-1.2	G535P	Pathogenic	0.871
NPC1	O15118-1.2	G535Q	Pathogenic	0.902
NPC1	O15118-1.2	G535R	Pathogenic	0.897
NPC1	O15118-1.2	G535S	Pathogenic	0.779
NPC1	O15118-1.2	G535T	Pathogenic	0.889
NPC1	O15118-1.2	G535V	Pathogenic	0.902
NPC1	O15118-1.2	G535W	Pathogenic	0.863
NPC1	O15118-1.2	G535Y	Pathogenic	0.926
NPC1	O15118-1.2	T536A	Pathogenic	0.525
NPC1	O15118-1.2	T536C	Pathogenic	0.537
NPC1	O15118-1.2	T536D	Pathogenic	0.504
NPC1	O15118-1.2	T536E	Pathogenic	0.536
NPC1	O15118-1.2	T536F	Pathogenic	0.617
NPC1	O15118-1.2	T536G	Pathogenic	0.715
NPC1	O15118-1.2	T536H	Pathogenic	0.699
NPC1	O15118-1.2	T536I	Pathogenic	0.505
NPC1	O15118-1.2	T536K	Pathogenic	0.546
NPC1	O15118-1.2	T536L	Pathogenic	0.513
NPC1	O15118-1.2	T536M	Pathogenic	0.552
NPC1	O15118-1.2	T536N	Neutral	0.424
NPC1	O15118-1.2	T536P	Pathogenic	0.552
NPC1	O15118-1.2	T536Q	Pathogenic	0.578
NPC1	O15118-1.2	T536R	Pathogenic	0.565
NPC1	O15118-1.2	T536S	Neutral	0.401
NPC1	O15118-1.2	T536V	Neutral	0.429
NPC1	O15118-1.2	T536W	Pathogenic	0.621
NPC1	O15118-1.2	T536Y	Pathogenic	0.687
NPC1	O15118-1.2	F537A	Pathogenic	0.842
NPC1	O15118-1.2	F537C	Pathogenic	0.856
NPC1	O15118-1.2	F537D	Pathogenic	0.826
NPC1	O15118-1.2	F537E	Pathogenic	0.816
NPC1	O15118-1.2	F537G	Pathogenic	0.888
NPC1	O15118-1.2	F537H	Pathogenic	0.715
NPC1	O15118-1.2	F537I	Pathogenic	0.74
NPC1	O15118-1.2	F537K	Pathogenic	0.772
NPC1	O15118-1.2	F537L	Pathogenic	0.735
NPC1	O15118-1.2	F537M	Pathogenic	0.704
NPC1	O15118-1.2	F537N	Pathogenic	0.83
NPC1	O15118-1.2	F537P	Pathogenic	0.92
NPC1	O15118-1.2	F537Q	Pathogenic	0.832
NPC1	O15118-1.2	F537R	Pathogenic	0.784
NPC1	O15118-1.2	F537S	Pathogenic	0.821
NPC1	O15118-1.2	F537T	Pathogenic	0.818
NPC1	O15118-1.2	F537V	Pathogenic	0.796
NPC1	O15118-1.2	F537W	Pathogenic	0.649
NPC1	O15118-1.2	F537Y	Neutral	0.398
NPC1	O15118-1.2	G538A	Pathogenic	0.94
NPC1	O15118-1.2	G538C	Pathogenic	0.978
NPC1	O15118-1.2	G538D	Pathogenic	0.958
NPC1	O15118-1.2	G538E	Pathogenic	0.975
NPC1	O15118-1.2	G538F	Pathogenic	0.979
NPC1	O15118-1.2	G538H	Pathogenic	0.98
NPC1	O15118-1.2	G538I	Pathogenic	0.984
NPC1	O15118-1.2	G538K	Pathogenic	0.976
NPC1	O15118-1.2	G538L	Pathogenic	0.985
NPC1	O15118-1.2	G538M	Pathogenic	0.981
NPC1	O15118-1.2	G538N	Pathogenic	0.944
NPC1	O15118-1.2	G538P	Pathogenic	0.971
NPC1	O15118-1.2	G538Q	Pathogenic	0.979
NPC1	O15118-1.2	G538R	Pathogenic	0.978
NPC1	O15118-1.2	G538S	Pathogenic	0.947
NPC1	O15118-1.2	G538T	Pathogenic	0.976
NPC1	O15118-1.2	G538V	Pathogenic	0.979
NPC1	O15118-1.2	G538W	Pathogenic	0.97
NPC1	O15118-1.2	G538Y	Pathogenic	0.984
NPC1	O15118-1.2	G539A	Pathogenic	0.863
NPC1	O15118-1.2	G539C	Pathogenic	0.947
NPC1	O15118-1.2	G539D	Pathogenic	0.902
NPC1	O15118-1.2	G539E	Pathogenic	0.94
NPC1	O15118-1.2	G539F	Pathogenic	0.949
NPC1	O15118-1.2	G539H	Pathogenic	0.952
NPC1	O15118-1.2	G539I	Pathogenic	0.962
NPC1	O15118-1.2	G539K	Pathogenic	0.942
NPC1	O15118-1.2	G539L	Pathogenic	0.963
NPC1	O15118-1.2	G539M	Pathogenic	0.954
NPC1	O15118-1.2	G539N	Pathogenic	0.872
NPC1	O15118-1.2	G539P	Pathogenic	0.932
NPC1	O15118-1.2	G539Q	Pathogenic	0.949
NPC1	O15118-1.2	G539R	Pathogenic	0.946
NPC1	O15118-1.2	G539S	Pathogenic	0.877
NPC1	O15118-1.2	G539T	Pathogenic	0.942
NPC1	O15118-1.2	G539V	Pathogenic	0.949
NPC1	O15118-1.2	G539W	Pathogenic	0.927
NPC1	O15118-1.2	G539Y	Pathogenic	0.962
NPC1	O15118-1.2	P540A	Pathogenic	0.959
NPC1	O15118-1.2	P540C	Pathogenic	0.979
NPC1	O15118-1.2	P540D	Pathogenic	0.935
NPC1	O15118-1.2	P540E	Pathogenic	0.944
NPC1	O15118-1.2	P540F	Pathogenic	0.986
NPC1	O15118-1.2	P540G	Pathogenic	0.972
NPC1	O15118-1.2	P540H	Pathogenic	0.971
NPC1	O15118-1.2	P540I	Pathogenic	0.977
NPC1	O15118-1.2	P540K	Pathogenic	0.946
NPC1	O15118-1.2	P540L	Pathogenic	0.978
NPC1	O15118-1.2	P540M	Pathogenic	0.973
NPC1	O15118-1.2	P540N	Pathogenic	0.958
NPC1	O15118-1.2	P540Q	Pathogenic	0.952
NPC1	O15118-1.2	P540R	Pathogenic	0.965
NPC1	O15118-1.2	P540S	Pathogenic	0.953
NPC1	O15118-1.2	P540T	Pathogenic	0.953
NPC1	O15118-1.2	P540V	Pathogenic	0.97
NPC1	O15118-1.2	P540W	Pathogenic	0.986
NPC1	O15118-1.2	P540Y	Pathogenic	0.985
NPC1	O15118-1.2	V541A	Pathogenic	0.769
NPC1	O15118-1.2	V541C	Pathogenic	0.845
NPC1	O15118-1.2	V541D	Pathogenic	0.865
NPC1	O15118-1.2	V541E	Pathogenic	0.811
NPC1	O15118-1.2	V541F	Pathogenic	0.839
NPC1	O15118-1.2	V541G	Pathogenic	0.915
NPC1	O15118-1.2	V541H	Pathogenic	0.896
NPC1	O15118-1.2	V541I	Pathogenic	0.509
NPC1	O15118-1.2	V541K	Pathogenic	0.817
NPC1	O15118-1.2	V541L	Pathogenic	0.699
NPC1	O15118-1.2	V541M	Pathogenic	0.731
NPC1	O15118-1.2	V541N	Pathogenic	0.868
NPC1	O15118-1.2	V541P	Pathogenic	0.878
NPC1	O15118-1.2	V541Q	Pathogenic	0.835
NPC1	O15118-1.2	V541R	Pathogenic	0.876
NPC1	O15118-1.2	V541S	Pathogenic	0.861
NPC1	O15118-1.2	V541T	Pathogenic	0.737
NPC1	O15118-1.2	V541W	Pathogenic	0.92
NPC1	O15118-1.2	V541Y	Pathogenic	0.857
NPC1	O15118-1.2	F542A	Pathogenic	0.766
NPC1	O15118-1.2	F542C	Pathogenic	0.785
NPC1	O15118-1.2	F542D	Pathogenic	0.744
NPC1	O15118-1.2	F542E	Pathogenic	0.731
NPC1	O15118-1.2	F542G	Pathogenic	0.83
NPC1	O15118-1.2	F542H	Pathogenic	0.606
NPC1	O15118-1.2	F542I	Pathogenic	0.635
NPC1	O15118-1.2	F542K	Pathogenic	0.674
NPC1	O15118-1.2	F542L	Pathogenic	0.63
NPC1	O15118-1.2	F542M	Pathogenic	0.593
NPC1	O15118-1.2	F542N	Pathogenic	0.749
NPC1	O15118-1.2	F542P	Pathogenic	0.876
NPC1	O15118-1.2	F542Q	Pathogenic	0.752
NPC1	O15118-1.2	F542R	Pathogenic	0.69
NPC1	O15118-1.2	F542S	Pathogenic	0.738
NPC1	O15118-1.2	F542T	Pathogenic	0.733
NPC1	O15118-1.2	F542V	Pathogenic	0.705
NPC1	O15118-1.2	F542W	Pathogenic	0.531
NPC1	O15118-1.2	F542Y	Neutral	0.288
NPC1	O15118-1.2	P543A	Pathogenic	0.961
NPC1	O15118-1.2	P543C	Pathogenic	0.98
NPC1	O15118-1.2	P543D	Pathogenic	0.938
NPC1	O15118-1.2	P543E	Pathogenic	0.946
NPC1	O15118-1.2	P543F	Pathogenic	0.986
NPC1	O15118-1.2	P543G	Pathogenic	0.973
NPC1	O15118-1.2	P543H	Pathogenic	0.972
NPC1	O15118-1.2	P543I	Pathogenic	0.978
NPC1	O15118-1.2	P543K	Pathogenic	0.948
NPC1	O15118-1.2	P543L	Pathogenic	0.979
NPC1	O15118-1.2	P543M	Pathogenic	0.974
NPC1	O15118-1.2	P543N	Pathogenic	0.96
NPC1	O15118-1.2	P543Q	Pathogenic	0.954
NPC1	O15118-1.2	P543R	Pathogenic	0.967
NPC1	O15118-1.2	P543S	Pathogenic	0.955
NPC1	O15118-1.2	P543T	Pathogenic	0.955
NPC1	O15118-1.2	P543V	Pathogenic	0.971
NPC1	O15118-1.2	P543W	Pathogenic	0.986
NPC1	O15118-1.2	P543Y	Pathogenic	0.985
NPC1	O15118-1.2	W544A	Pathogenic	0.892
NPC1	O15118-1.2	W544C	Pathogenic	0.862
NPC1	O15118-1.2	W544D	Pathogenic	0.88
NPC1	O15118-1.2	W544E	Pathogenic	0.823
NPC1	O15118-1.2	W544F	Pathogenic	0.656
NPC1	O15118-1.2	W544G	Pathogenic	0.85
NPC1	O15118-1.2	W544H	Pathogenic	0.795
NPC1	O15118-1.2	W544I	Pathogenic	0.905
NPC1	O15118-1.2	W544K	Pathogenic	0.78
NPC1	O15118-1.2	W544L	Pathogenic	0.863
NPC1	O15118-1.2	W544M	Pathogenic	0.785
NPC1	O15118-1.2	W544N	Pathogenic	0.882
NPC1	O15118-1.2	W544P	Pathogenic	0.923
NPC1	O15118-1.2	W544Q	Pathogenic	0.779
NPC1	O15118-1.2	W544R	Pathogenic	0.765
NPC1	O15118-1.2	W544S	Pathogenic	0.876
NPC1	O15118-1.2	W544T	Pathogenic	0.824
NPC1	O15118-1.2	W544V	Pathogenic	0.898
NPC1	O15118-1.2	W544Y	Neutral	0.487
NPC1	O15118-1.2	L545A	Pathogenic	0.653
NPC1	O15118-1.2	L545C	Pathogenic	0.678
NPC1	O15118-1.2	L545D	Pathogenic	0.784
NPC1	O15118-1.2	L545E	Pathogenic	0.698
NPC1	O15118-1.2	L545F	Pathogenic	0.6
NPC1	O15118-1.2	L545G	Pathogenic	0.859
NPC1	O15118-1.2	L545H	Pathogenic	0.739
NPC1	O15118-1.2	L545I	Neutral	0.392
NPC1	O15118-1.2	L545K	Pathogenic	0.577
NPC1	O15118-1.2	L545M	Neutral	0.363
NPC1	O15118-1.2	L545N	Pathogenic	0.717
NPC1	O15118-1.2	L545P	Pathogenic	0.803
NPC1	O15118-1.2	L545Q	Pathogenic	0.637
NPC1	O15118-1.2	L545R	Pathogenic	0.595
NPC1	O15118-1.2	L545S	Pathogenic	0.705
NPC1	O15118-1.2	L545T	Pathogenic	0.613
NPC1	O15118-1.2	L545V	Neutral	0.484
NPC1	O15118-1.2	L545W	Pathogenic	0.767
NPC1	O15118-1.2	L545Y	Pathogenic	0.648
NPC1	O15118-1.2	V546A	Pathogenic	0.636
NPC1	O15118-1.2	V546C	Pathogenic	0.741
NPC1	O15118-1.2	V546D	Pathogenic	0.771
NPC1	O15118-1.2	V546E	Pathogenic	0.692
NPC1	O15118-1.2	V546F	Pathogenic	0.733
NPC1	O15118-1.2	V546G	Pathogenic	0.849
NPC1	O15118-1.2	V546H	Pathogenic	0.818
NPC1	O15118-1.2	V546I	Neutral	0.353
NPC1	O15118-1.2	V546K	Pathogenic	0.701
NPC1	O15118-1.2	V546L	Pathogenic	0.55
NPC1	O15118-1.2	V546M	Pathogenic	0.588
NPC1	O15118-1.2	V546N	Pathogenic	0.775
NPC1	O15118-1.2	V546P	Pathogenic	0.79
NPC1	O15118-1.2	V546Q	Pathogenic	0.727
NPC1	O15118-1.2	V546R	Pathogenic	0.787
NPC1	O15118-1.2	V546S	Pathogenic	0.765
NPC1	O15118-1.2	V546T	Pathogenic	0.595
NPC1	O15118-1.2	V546W	Pathogenic	0.858
NPC1	O15118-1.2	V546Y	Pathogenic	0.759
NPC1	O15118-1.2	L547A	Pathogenic	0.796
NPC1	O15118-1.2	L547C	Pathogenic	0.813
NPC1	O15118-1.2	L547D	Pathogenic	0.882
NPC1	O15118-1.2	L547E	Pathogenic	0.827
NPC1	O15118-1.2	L547F	Pathogenic	0.756
NPC1	O15118-1.2	L547G	Pathogenic	0.926
NPC1	O15118-1.2	L547H	Pathogenic	0.854
NPC1	O15118-1.2	L547I	Pathogenic	0.572
NPC1	O15118-1.2	L547K	Pathogenic	0.738
NPC1	O15118-1.2	L547M	Pathogenic	0.542
NPC1	O15118-1.2	L547N	Pathogenic	0.84
NPC1	O15118-1.2	L547P	Pathogenic	0.894
NPC1	O15118-1.2	L547Q	Pathogenic	0.784
NPC1	O15118-1.2	L547R	Pathogenic	0.752
NPC1	O15118-1.2	L547S	Pathogenic	0.832
NPC1	O15118-1.2	L547T	Pathogenic	0.766
NPC1	O15118-1.2	L547V	Pathogenic	0.66
NPC1	O15118-1.2	L547W	Pathogenic	0.872
NPC1	O15118-1.2	L547Y	Pathogenic	0.792
NPC1	O15118-1.2	G548A	Pathogenic	0.944
NPC1	O15118-1.2	G548C	Pathogenic	0.98
NPC1	O15118-1.2	G548D	Pathogenic	0.961
NPC1	O15118-1.2	G548E	Pathogenic	0.977
NPC1	O15118-1.2	G548F	Pathogenic	0.98
NPC1	O15118-1.2	G548H	Pathogenic	0.981
NPC1	O15118-1.2	G548I	Pathogenic	0.985
NPC1	O15118-1.2	G548K	Pathogenic	0.978
NPC1	O15118-1.2	G548L	Pathogenic	0.986
NPC1	O15118-1.2	G548M	Pathogenic	0.982
NPC1	O15118-1.2	G548N	Pathogenic	0.948
NPC1	O15118-1.2	G548P	Pathogenic	0.973
NPC1	O15118-1.2	G548Q	Pathogenic	0.98
NPC1	O15118-1.2	G548R	Pathogenic	0.979
NPC1	O15118-1.2	G548S	Pathogenic	0.95
NPC1	O15118-1.2	G548T	Pathogenic	0.977
NPC1	O15118-1.2	G548V	Pathogenic	0.98
NPC1	O15118-1.2	G548W	Pathogenic	0.972
NPC1	O15118-1.2	G548Y	Pathogenic	0.985
NPC1	O15118-1.2	G549A	Pathogenic	0.929
NPC1	O15118-1.2	G549C	Pathogenic	0.974
NPC1	O15118-1.2	G549D	Pathogenic	0.95
NPC1	O15118-1.2	G549E	Pathogenic	0.97
NPC1	O15118-1.2	G549F	Pathogenic	0.974
NPC1	O15118-1.2	G549H	Pathogenic	0.976
NPC1	O15118-1.2	G549I	Pathogenic	0.981
NPC1	O15118-1.2	G549K	Pathogenic	0.971
NPC1	O15118-1.2	G549L	Pathogenic	0.982
NPC1	O15118-1.2	G549M	Pathogenic	0.977
NPC1	O15118-1.2	G549N	Pathogenic	0.934
NPC1	O15118-1.2	G549P	Pathogenic	0.966
NPC1	O15118-1.2	G549Q	Pathogenic	0.975
NPC1	O15118-1.2	G549R	Pathogenic	0.973
NPC1	O15118-1.2	G549S	Pathogenic	0.937
NPC1	O15118-1.2	G549T	Pathogenic	0.971
NPC1	O15118-1.2	G549V	Pathogenic	0.975
NPC1	O15118-1.2	G549W	Pathogenic	0.963
NPC1	O15118-1.2	G549Y	Pathogenic	0.981
NPC1	O15118-1.2	Y550A	Pathogenic	0.92
NPC1	O15118-1.2	Y550C	Pathogenic	0.927
NPC1	O15118-1.2	Y550D	Pathogenic	0.911
NPC1	O15118-1.2	Y550E	Pathogenic	0.867
NPC1	O15118-1.2	Y550F	Pathogenic	0.512
NPC1	O15118-1.2	Y550G	Pathogenic	0.945
NPC1	O15118-1.2	Y550H	Pathogenic	0.631
NPC1	O15118-1.2	Y550I	Pathogenic	0.839
NPC1	O15118-1.2	Y550K	Pathogenic	0.833
NPC1	O15118-1.2	Y550L	Pathogenic	0.844
NPC1	O15118-1.2	Y550M	Pathogenic	0.863
NPC1	O15118-1.2	Y550N	Pathogenic	0.878
NPC1	O15118-1.2	Y550P	Pathogenic	0.944
NPC1	O15118-1.2	Y550Q	Pathogenic	0.832
NPC1	O15118-1.2	Y550R	Pathogenic	0.833
NPC1	O15118-1.2	Y550S	Pathogenic	0.909
NPC1	O15118-1.2	Y550T	Pathogenic	0.907
NPC1	O15118-1.2	Y550V	Pathogenic	0.877
NPC1	O15118-1.2	Y550W	Pathogenic	0.593
NPC1	O15118-1.2	D551A	Pathogenic	0.513
NPC1	O15118-1.2	D551C	Pathogenic	0.525
NPC1	O15118-1.2	D551E	Neutral	0.229
NPC1	O15118-1.2	D551F	Pathogenic	0.517
NPC1	O15118-1.2	D551G	Neutral	0.471
NPC1	O15118-1.2	D551H	Neutral	0.436
NPC1	O15118-1.2	D551I	Neutral	0.499
NPC1	O15118-1.2	D551K	Pathogenic	0.518
NPC1	O15118-1.2	D551L	Pathogenic	0.603
NPC1	O15118-1.2	D551M	Pathogenic	0.546
NPC1	O15118-1.2	D551N	Neutral	0.286
NPC1	O15118-1.2	D551P	Neutral	0.352
NPC1	O15118-1.2	D551Q	Neutral	0.366
NPC1	O15118-1.2	D551R	Pathogenic	0.63
NPC1	O15118-1.2	D551S	Neutral	0.345
NPC1	O15118-1.2	D551T	Neutral	0.39
NPC1	O15118-1.2	D551V	Pathogenic	0.519
NPC1	O15118-1.2	D551W	Pathogenic	0.615
NPC1	O15118-1.2	D551Y	Pathogenic	0.594
NPC1	O15118-1.2	D552A	Pathogenic	0.561
NPC1	O15118-1.2	D552C	Pathogenic	0.573
NPC1	O15118-1.2	D552E	Neutral	0.265
NPC1	O15118-1.2	D552F	Pathogenic	0.565
NPC1	O15118-1.2	D552G	Pathogenic	0.519
NPC1	O15118-1.2	D552H	Neutral	0.484
NPC1	O15118-1.2	D552I	Pathogenic	0.547
NPC1	O15118-1.2	D552K	Pathogenic	0.566
NPC1	O15118-1.2	D552L	Pathogenic	0.648
NPC1	O15118-1.2	D552M	Pathogenic	0.594
NPC1	O15118-1.2	D552N	Neutral	0.326
NPC1	O15118-1.2	D552P	Neutral	0.398
NPC1	O15118-1.2	D552Q	Neutral	0.412
NPC1	O15118-1.2	D552R	Pathogenic	0.674
NPC1	O15118-1.2	D552S	Neutral	0.39
NPC1	O15118-1.2	D552T	Neutral	0.436
NPC1	O15118-1.2	D552V	Pathogenic	0.567
NPC1	O15118-1.2	D552W	Pathogenic	0.66
NPC1	O15118-1.2	D552Y	Pathogenic	0.639
NPC1	O15118-1.2	Q553A	Neutral	0.355
NPC1	O15118-1.2	Q553C	Neutral	0.459
NPC1	O15118-1.2	Q553D	Neutral	0.243
NPC1	O15118-1.2	Q553E	Neutral	0.122
NPC1	O15118-1.2	Q553F	Neutral	0.384
NPC1	O15118-1.2	Q553G	Pathogenic	0.502
NPC1	O15118-1.2	Q553H	Neutral	0.234
NPC1	O15118-1.2	Q553I	Neutral	0.367
NPC1	O15118-1.2	Q553K	Neutral	0.167
NPC1	O15118-1.2	Q553L	Neutral	0.29
NPC1	O15118-1.2	Q553M	Neutral	0.181
NPC1	O15118-1.2	Q553N	Neutral	0.248
NPC1	O15118-1.2	Q553P	Neutral	0.295
NPC1	O15118-1.2	Q553R	Neutral	0.178
NPC1	O15118-1.2	Q553S	Neutral	0.288
NPC1	O15118-1.2	Q553T	Neutral	0.324
NPC1	O15118-1.2	Q553V	Neutral	0.322
NPC1	O15118-1.2	Q553W	Neutral	0.301
NPC1	O15118-1.2	Q553Y	Neutral	0.282
NPC1	O15118-1.2	N554A	Pathogenic	0.589
NPC1	O15118-1.2	N554C	Pathogenic	0.601
NPC1	O15118-1.2	N554D	Neutral	0.333
NPC1	O15118-1.2	N554E	Neutral	0.446
NPC1	O15118-1.2	N554F	Pathogenic	0.578
NPC1	O15118-1.2	N554G	Neutral	0.452
NPC1	O15118-1.2	N554H	Neutral	0.314
NPC1	O15118-1.2	N554I	Pathogenic	0.561
NPC1	O15118-1.2	N554K	Neutral	0.456
NPC1	O15118-1.2	N554L	Pathogenic	0.569
NPC1	O15118-1.2	N554M	Pathogenic	0.512
NPC1	O15118-1.2	N554P	Pathogenic	0.521
NPC1	O15118-1.2	N554Q	Neutral	0.425
NPC1	O15118-1.2	N554R	Neutral	0.474
NPC1	O15118-1.2	N554S	Neutral	0.328
NPC1	O15118-1.2	N554T	Neutral	0.366
NPC1	O15118-1.2	N554V	Pathogenic	0.58
NPC1	O15118-1.2	N554W	Pathogenic	0.672
NPC1	O15118-1.2	N554Y	Pathogenic	0.56
NPC1	O15118-1.2	Y555A	Pathogenic	0.968
NPC1	O15118-1.2	Y555C	Pathogenic	0.971
NPC1	O15118-1.2	Y555D	Pathogenic	0.964
NPC1	O15118-1.2	Y555E	Pathogenic	0.944
NPC1	O15118-1.2	Y555F	Pathogenic	0.732
NPC1	O15118-1.2	Y555G	Pathogenic	0.978
NPC1	O15118-1.2	Y555H	Pathogenic	0.816
NPC1	O15118-1.2	Y555I	Pathogenic	0.931
NPC1	O15118-1.2	Y555K	Pathogenic	0.928
NPC1	O15118-1.2	Y555L	Pathogenic	0.934
NPC1	O15118-1.2	Y555M	Pathogenic	0.943
NPC1	O15118-1.2	Y555N	Pathogenic	0.949
NPC1	O15118-1.2	Y555P	Pathogenic	0.978
NPC1	O15118-1.2	Y555Q	Pathogenic	0.928
NPC1	O15118-1.2	Y555R	Pathogenic	0.928
NPC1	O15118-1.2	Y555S	Pathogenic	0.963
NPC1	O15118-1.2	Y555T	Pathogenic	0.962
NPC1	O15118-1.2	Y555V	Pathogenic	0.949
NPC1	O15118-1.2	Y555W	Pathogenic	0.791
NPC1	O15118-1.2	N556A	Pathogenic	0.564
NPC1	O15118-1.2	N556C	Pathogenic	0.575
NPC1	O15118-1.2	N556D	Neutral	0.31
NPC1	O15118-1.2	N556E	Neutral	0.42
NPC1	O15118-1.2	N556F	Pathogenic	0.552
NPC1	O15118-1.2	N556G	Neutral	0.426
NPC1	O15118-1.2	N556H	Neutral	0.292
NPC1	O15118-1.2	N556I	Pathogenic	0.535
NPC1	O15118-1.2	N556K	Neutral	0.43
NPC1	O15118-1.2	N556L	Pathogenic	0.543
NPC1	O15118-1.2	N556M	Neutral	0.486
NPC1	O15118-1.2	N556P	Neutral	0.495
NPC1	O15118-1.2	N556Q	Neutral	0.4
NPC1	O15118-1.2	N556R	Neutral	0.448
NPC1	O15118-1.2	N556S	Neutral	0.305
NPC1	O15118-1.2	N556T	Neutral	0.342
NPC1	O15118-1.2	N556V	Pathogenic	0.554
NPC1	O15118-1.2	N556W	Pathogenic	0.648
NPC1	O15118-1.2	N556Y	Pathogenic	0.534
NPC1	O15118-1.2	N557A	Pathogenic	0.703
NPC1	O15118-1.2	N557C	Pathogenic	0.713
NPC1	O15118-1.2	N557D	Neutral	0.452
NPC1	O15118-1.2	N557E	Pathogenic	0.571
NPC1	O15118-1.2	N557F	Pathogenic	0.694
NPC1	O15118-1.2	N557G	Pathogenic	0.577
NPC1	O15118-1.2	N557H	Neutral	0.431
NPC1	O15118-1.2	N557I	Pathogenic	0.678
NPC1	O15118-1.2	N557K	Pathogenic	0.581
NPC1	O15118-1.2	N557L	Pathogenic	0.686
NPC1	O15118-1.2	N557M	Pathogenic	0.634
NPC1	O15118-1.2	N557P	Pathogenic	0.643
NPC1	O15118-1.2	N557Q	Pathogenic	0.55
NPC1	O15118-1.2	N557R	Pathogenic	0.599
NPC1	O15118-1.2	N557S	Neutral	0.446
NPC1	O15118-1.2	N557T	Neutral	0.488
NPC1	O15118-1.2	N557V	Pathogenic	0.696
NPC1	O15118-1.2	N557W	Pathogenic	0.772
NPC1	O15118-1.2	N557Y	Pathogenic	0.678
NPC1	O15118-1.2	A558C	Pathogenic	0.919
NPC1	O15118-1.2	A558D	Pathogenic	0.957
NPC1	O15118-1.2	A558E	Pathogenic	0.946
NPC1	O15118-1.2	A558F	Pathogenic	0.962
NPC1	O15118-1.2	A558G	Pathogenic	0.927
NPC1	O15118-1.2	A558H	Pathogenic	0.972
NPC1	O15118-1.2	A558I	Pathogenic	0.941
NPC1	O15118-1.2	A558K	Pathogenic	0.948
NPC1	O15118-1.2	A558L	Pathogenic	0.943
NPC1	O15118-1.2	A558M	Pathogenic	0.951
NPC1	O15118-1.2	A558N	Pathogenic	0.96
NPC1	O15118-1.2	A558P	Pathogenic	0.949
NPC1	O15118-1.2	A558Q	Pathogenic	0.954
NPC1	O15118-1.2	A558R	Pathogenic	0.951
NPC1	O15118-1.2	A558S	Pathogenic	0.888
NPC1	O15118-1.2	A558T	Pathogenic	0.936
NPC1	O15118-1.2	A558V	Pathogenic	0.922
NPC1	O15118-1.2	A558W	Pathogenic	0.974
NPC1	O15118-1.2	A558Y	Pathogenic	0.972
NPC1	O15118-1.2	T559A	Pathogenic	0.786
NPC1	O15118-1.2	T559C	Pathogenic	0.794
NPC1	O15118-1.2	T559D	Pathogenic	0.772
NPC1	O15118-1.2	T559E	Pathogenic	0.794
NPC1	O15118-1.2	T559F	Pathogenic	0.843
NPC1	O15118-1.2	T559G	Pathogenic	0.893
NPC1	O15118-1.2	T559H	Pathogenic	0.885
NPC1	O15118-1.2	T559I	Pathogenic	0.772
NPC1	O15118-1.2	T559K	Pathogenic	0.8
NPC1	O15118-1.2	T559L	Pathogenic	0.778
NPC1	O15118-1.2	T559M	Pathogenic	0.804
NPC1	O15118-1.2	T559N	Pathogenic	0.71
NPC1	O15118-1.2	T559P	Pathogenic	0.804
NPC1	O15118-1.2	T559Q	Pathogenic	0.82
NPC1	O15118-1.2	T559R	Pathogenic	0.812
NPC1	O15118-1.2	T559S	Pathogenic	0.69
NPC1	O15118-1.2	T559V	Pathogenic	0.714
NPC1	O15118-1.2	T559W	Pathogenic	0.845
NPC1	O15118-1.2	T559Y	Pathogenic	0.88
NPC1	O15118-1.2	A560C	Pathogenic	0.915
NPC1	O15118-1.2	A560D	Pathogenic	0.955
NPC1	O15118-1.2	A560E	Pathogenic	0.944
NPC1	O15118-1.2	A560F	Pathogenic	0.96
NPC1	O15118-1.2	A560G	Pathogenic	0.924
NPC1	O15118-1.2	A560H	Pathogenic	0.971
NPC1	O15118-1.2	A560I	Pathogenic	0.939
NPC1	O15118-1.2	A560K	Pathogenic	0.946
NPC1	O15118-1.2	A560L	Pathogenic	0.94
NPC1	O15118-1.2	A560M	Pathogenic	0.949
NPC1	O15118-1.2	A560N	Pathogenic	0.958
NPC1	O15118-1.2	A560P	Pathogenic	0.947
NPC1	O15118-1.2	A560Q	Pathogenic	0.952
NPC1	O15118-1.2	A560R	Pathogenic	0.949
NPC1	O15118-1.2	A560S	Pathogenic	0.884
NPC1	O15118-1.2	A560T	Pathogenic	0.933
NPC1	O15118-1.2	A560V	Pathogenic	0.918
NPC1	O15118-1.2	A560W	Pathogenic	0.973
NPC1	O15118-1.2	A560Y	Pathogenic	0.971
NPC1	O15118-1.2	L561A	Pathogenic	0.693
NPC1	O15118-1.2	L561C	Pathogenic	0.716
NPC1	O15118-1.2	L561D	Pathogenic	0.813
NPC1	O15118-1.2	L561E	Pathogenic	0.734
NPC1	O15118-1.2	L561F	Pathogenic	0.642
NPC1	O15118-1.2	L561G	Pathogenic	0.879
NPC1	O15118-1.2	L561H	Pathogenic	0.772
NPC1	O15118-1.2	L561I	Neutral	0.435
NPC1	O15118-1.2	L561K	Pathogenic	0.62
NPC1	O15118-1.2	L561M	Neutral	0.406
NPC1	O15118-1.2	L561N	Pathogenic	0.752
NPC1	O15118-1.2	L561P	Pathogenic	0.83
NPC1	O15118-1.2	L561Q	Pathogenic	0.677
NPC1	O15118-1.2	L561R	Pathogenic	0.637
NPC1	O15118-1.2	L561S	Pathogenic	0.741
NPC1	O15118-1.2	L561T	Pathogenic	0.655
NPC1	O15118-1.2	L561V	Pathogenic	0.529
NPC1	O15118-1.2	L561W	Pathogenic	0.798
NPC1	O15118-1.2	L561Y	Pathogenic	0.688
NPC1	O15118-1.2	V562A	Pathogenic	0.754
NPC1	O15118-1.2	V562C	Pathogenic	0.834
NPC1	O15118-1.2	V562D	Pathogenic	0.855
NPC1	O15118-1.2	V562E	Pathogenic	0.798
NPC1	O15118-1.2	V562F	Pathogenic	0.828
NPC1	O15118-1.2	V562G	Pathogenic	0.908
NPC1	O15118-1.2	V562H	Pathogenic	0.888
NPC1	O15118-1.2	V562I	Neutral	0.489
NPC1	O15118-1.2	V562K	Pathogenic	0.804
NPC1	O15118-1.2	V562L	Pathogenic	0.681
NPC1	O15118-1.2	V562M	Pathogenic	0.714
NPC1	O15118-1.2	V562N	Pathogenic	0.858
NPC1	O15118-1.2	V562P	Pathogenic	0.869
NPC1	O15118-1.2	V562Q	Pathogenic	0.824
NPC1	O15118-1.2	V562R	Pathogenic	0.867
NPC1	O15118-1.2	V562S	Pathogenic	0.851
NPC1	O15118-1.2	V562T	Pathogenic	0.72
NPC1	O15118-1.2	V562W	Pathogenic	0.913
NPC1	O15118-1.2	V562Y	Pathogenic	0.847
NPC1	O15118-1.2	I563A	Pathogenic	0.749
NPC1	O15118-1.2	I563C	Pathogenic	0.769
NPC1	O15118-1.2	I563D	Pathogenic	0.796
NPC1	O15118-1.2	I563E	Pathogenic	0.785
NPC1	O15118-1.2	I563F	Pathogenic	0.715
NPC1	O15118-1.2	I563G	Pathogenic	0.906
NPC1	O15118-1.2	I563H	Pathogenic	0.817
NPC1	O15118-1.2	I563K	Pathogenic	0.76
NPC1	O15118-1.2	I563L	Pathogenic	0.513
NPC1	O15118-1.2	I563M	Pathogenic	0.57
NPC1	O15118-1.2	I563N	Pathogenic	0.8
NPC1	O15118-1.2	I563P	Pathogenic	0.865
NPC1	O15118-1.2	I563Q	Pathogenic	0.803
NPC1	O15118-1.2	I563R	Pathogenic	0.773
NPC1	O15118-1.2	I563S	Pathogenic	0.79
NPC1	O15118-1.2	I563T	Pathogenic	0.715
NPC1	O15118-1.2	I563V	Neutral	0.406
NPC1	O15118-1.2	I563W	Pathogenic	0.891
NPC1	O15118-1.2	I563Y	Pathogenic	0.744
NPC1	O15118-1.2	T564A	Pathogenic	0.942
NPC1	O15118-1.2	T564C	Pathogenic	0.945
NPC1	O15118-1.2	T564D	Pathogenic	0.938
NPC1	O15118-1.2	T564E	Pathogenic	0.945
NPC1	O15118-1.2	T564F	Pathogenic	0.96
NPC1	O15118-1.2	T564G	Pathogenic	0.974
NPC1	O15118-1.2	T564H	Pathogenic	0.972
NPC1	O15118-1.2	T564I	Pathogenic	0.938
NPC1	O15118-1.2	T564K	Pathogenic	0.947
NPC1	O15118-1.2	T564L	Pathogenic	0.94
NPC1	O15118-1.2	T564M	Pathogenic	0.948
NPC1	O15118-1.2	T564N	Pathogenic	0.916
NPC1	O15118-1.2	T564P	Pathogenic	0.948
NPC1	O15118-1.2	T564Q	Pathogenic	0.953
NPC1	O15118-1.2	T564R	Pathogenic	0.95
NPC1	O15118-1.2	T564S	Pathogenic	0.908
NPC1	O15118-1.2	T564V	Pathogenic	0.917
NPC1	O15118-1.2	T564W	Pathogenic	0.96
NPC1	O15118-1.2	T564Y	Pathogenic	0.97
NPC1	O15118-1.2	F565A	Pathogenic	0.91
NPC1	O15118-1.2	F565C	Pathogenic	0.919
NPC1	O15118-1.2	F565D	Pathogenic	0.9
NPC1	O15118-1.2	F565E	Pathogenic	0.894
NPC1	O15118-1.2	F565G	Pathogenic	0.938
NPC1	O15118-1.2	F565H	Pathogenic	0.827
NPC1	O15118-1.2	F565I	Pathogenic	0.844
NPC1	O15118-1.2	F565K	Pathogenic	0.865
NPC1	O15118-1.2	F565L	Pathogenic	0.84
NPC1	O15118-1.2	F565M	Pathogenic	0.818
NPC1	O15118-1.2	F565N	Pathogenic	0.902
NPC1	O15118-1.2	F565P	Pathogenic	0.956
NPC1	O15118-1.2	F565Q	Pathogenic	0.904
NPC1	O15118-1.2	F565R	Pathogenic	0.873
NPC1	O15118-1.2	F565S	Pathogenic	0.897
NPC1	O15118-1.2	F565T	Pathogenic	0.895
NPC1	O15118-1.2	F565V	Pathogenic	0.881
NPC1	O15118-1.2	F565W	Pathogenic	0.778
NPC1	O15118-1.2	F565Y	Pathogenic	0.557
NPC1	O15118-1.2	P566A	Pathogenic	0.666
NPC1	O15118-1.2	P566C	Pathogenic	0.802
NPC1	O15118-1.2	P566D	Pathogenic	0.55
NPC1	O15118-1.2	P566E	Pathogenic	0.587
NPC1	O15118-1.2	P566F	Pathogenic	0.853
NPC1	O15118-1.2	P566G	Pathogenic	0.748
NPC1	O15118-1.2	P566H	Pathogenic	0.74
NPC1	O15118-1.2	P566I	Pathogenic	0.787
NPC1	O15118-1.2	P566K	Pathogenic	0.597
NPC1	O15118-1.2	P566L	Pathogenic	0.792
NPC1	O15118-1.2	P566M	Pathogenic	0.752
NPC1	O15118-1.2	P566N	Pathogenic	0.662
NPC1	O15118-1.2	P566Q	Pathogenic	0.627
NPC1	O15118-1.2	P566R	Pathogenic	0.701
NPC1	O15118-1.2	P566S	Pathogenic	0.632
NPC1	O15118-1.2	P566T	Pathogenic	0.635
NPC1	O15118-1.2	P566V	Pathogenic	0.731
NPC1	O15118-1.2	P566W	Pathogenic	0.855
NPC1	O15118-1.2	P566Y	Pathogenic	0.844
NPC1	O15118-1.2	V567A	Pathogenic	0.814
NPC1	O15118-1.2	V567C	Pathogenic	0.878
NPC1	O15118-1.2	V567D	Pathogenic	0.894
NPC1	O15118-1.2	V567E	Pathogenic	0.849
NPC1	O15118-1.2	V567F	Pathogenic	0.873
NPC1	O15118-1.2	V567G	Pathogenic	0.934
NPC1	O15118-1.2	V567H	Pathogenic	0.919
NPC1	O15118-1.2	V567I	Pathogenic	0.577
NPC1	O15118-1.2	V567K	Pathogenic	0.854
NPC1	O15118-1.2	V567L	Pathogenic	0.753
NPC1	O15118-1.2	V567M	Pathogenic	0.781
NPC1	O15118-1.2	V567N	Pathogenic	0.896
NPC1	O15118-1.2	V567P	Pathogenic	0.904
NPC1	O15118-1.2	V567Q	Pathogenic	0.87
NPC1	O15118-1.2	V567R	Pathogenic	0.903
NPC1	O15118-1.2	V567S	Pathogenic	0.891
NPC1	O15118-1.2	V567T	Pathogenic	0.786
NPC1	O15118-1.2	V567W	Pathogenic	0.938
NPC1	O15118-1.2	V567Y	Pathogenic	0.888
NPC1	O15118-1.2	N568A	Pathogenic	0.781
NPC1	O15118-1.2	N568C	Pathogenic	0.788
NPC1	O15118-1.2	N568D	Pathogenic	0.553
NPC1	O15118-1.2	N568E	Pathogenic	0.666
NPC1	O15118-1.2	N568F	Pathogenic	0.773
NPC1	O15118-1.2	N568G	Pathogenic	0.671
NPC1	O15118-1.2	N568H	Pathogenic	0.532
NPC1	O15118-1.2	N568I	Pathogenic	0.76
NPC1	O15118-1.2	N568K	Pathogenic	0.675
NPC1	O15118-1.2	N568L	Pathogenic	0.766
NPC1	O15118-1.2	N568M	Pathogenic	0.722
NPC1	O15118-1.2	N568P	Pathogenic	0.73
NPC1	O15118-1.2	N568Q	Pathogenic	0.647
NPC1	O15118-1.2	N568R	Pathogenic	0.691
NPC1	O15118-1.2	N568S	Pathogenic	0.547
NPC1	O15118-1.2	N568T	Pathogenic	0.588
NPC1	O15118-1.2	N568V	Pathogenic	0.774
NPC1	O15118-1.2	N568W	Pathogenic	0.835
NPC1	O15118-1.2	N568Y	Pathogenic	0.759
NPC1	O15118-1.2	N569A	Pathogenic	0.972
NPC1	O15118-1.2	N569C	Pathogenic	0.973
NPC1	O15118-1.2	N569D	Pathogenic	0.924
NPC1	O15118-1.2	N569E	Pathogenic	0.952
NPC1	O15118-1.2	N569F	Pathogenic	0.971
NPC1	O15118-1.2	N569G	Pathogenic	0.953
NPC1	O15118-1.2	N569H	Pathogenic	0.918
NPC1	O15118-1.2	N569I	Pathogenic	0.969
NPC1	O15118-1.2	N569K	Pathogenic	0.953
NPC1	O15118-1.2	N569L	Pathogenic	0.97
NPC1	O15118-1.2	N569M	Pathogenic	0.962
NPC1	O15118-1.2	N569P	Pathogenic	0.964
NPC1	O15118-1.2	N569Q	Pathogenic	0.948
NPC1	O15118-1.2	N569R	Pathogenic	0.957
NPC1	O15118-1.2	N569S	Pathogenic	0.923
NPC1	O15118-1.2	N569T	Pathogenic	0.934
NPC1	O15118-1.2	N569V	Pathogenic	0.971
NPC1	O15118-1.2	N569W	Pathogenic	0.98
NPC1	O15118-1.2	N569Y	Pathogenic	0.969
NPC1	O15118-1.2	Y570A	Pathogenic	0.924
NPC1	O15118-1.2	Y570C	Pathogenic	0.93
NPC1	O15118-1.2	Y570D	Pathogenic	0.915
NPC1	O15118-1.2	Y570E	Pathogenic	0.873
NPC1	O15118-1.2	Y570F	Pathogenic	0.524
NPC1	O15118-1.2	Y570G	Pathogenic	0.947
NPC1	O15118-1.2	Y570H	Pathogenic	0.642
NPC1	O15118-1.2	Y570I	Pathogenic	0.846
NPC1	O15118-1.2	Y570K	Pathogenic	0.839
NPC1	O15118-1.2	Y570L	Pathogenic	0.85
NPC1	O15118-1.2	Y570M	Pathogenic	0.869
NPC1	O15118-1.2	Y570N	Pathogenic	0.883
NPC1	O15118-1.2	Y570P	Pathogenic	0.947
NPC1	O15118-1.2	Y570Q	Pathogenic	0.839
NPC1	O15118-1.2	Y570R	Pathogenic	0.839
NPC1	O15118-1.2	Y570S	Pathogenic	0.912
NPC1	O15118-1.2	Y570T	Pathogenic	0.911
NPC1	O15118-1.2	Y570V	Pathogenic	0.882
NPC1	O15118-1.2	Y570W	Pathogenic	0.605
NPC1	O15118-1.2	Y571A	Pathogenic	0.661
NPC1	O15118-1.2	Y571C	Pathogenic	0.682
NPC1	O15118-1.2	Y571D	Pathogenic	0.634
NPC1	O15118-1.2	Y571E	Pathogenic	0.525
NPC1	O15118-1.2	Y571F	Neutral	0.151
NPC1	O15118-1.2	Y571G	Pathogenic	0.744
NPC1	O15118-1.2	Y571H	Neutral	0.224
NPC1	O15118-1.2	Y571I	Neutral	0.469
NPC1	O15118-1.2	Y571K	Neutral	0.457
NPC1	O15118-1.2	Y571L	Neutral	0.477
NPC1	O15118-1.2	Y571M	Pathogenic	0.516
NPC1	O15118-1.2	Y571N	Pathogenic	0.548
NPC1	O15118-1.2	Y571P	Pathogenic	0.741
NPC1	O15118-1.2	Y571Q	Neutral	0.456
NPC1	O15118-1.2	Y571R	Neutral	0.457
NPC1	O15118-1.2	Y571S	Pathogenic	0.627
NPC1	O15118-1.2	Y571T	Pathogenic	0.621
NPC1	O15118-1.2	Y571V	Pathogenic	0.546
NPC1	O15118-1.2	Y571W	Neutral	0.198
NPC1	O15118-1.2	N572A	Pathogenic	0.867
NPC1	O15118-1.2	N572C	Pathogenic	0.872
NPC1	O15118-1.2	N572D	Pathogenic	0.694
NPC1	O15118-1.2	N572E	Pathogenic	0.785
NPC1	O15118-1.2	N572F	Pathogenic	0.862
NPC1	O15118-1.2	N572G	Pathogenic	0.79
NPC1	O15118-1.2	N572H	Pathogenic	0.676
NPC1	O15118-1.2	N572I	Pathogenic	0.853
NPC1	O15118-1.2	N572K	Pathogenic	0.792
NPC1	O15118-1.2	N572L	Pathogenic	0.857
NPC1	O15118-1.2	N572M	Pathogenic	0.827
NPC1	O15118-1.2	N572P	Pathogenic	0.832
NPC1	O15118-1.2	N572Q	Pathogenic	0.771
NPC1	O15118-1.2	N572R	Pathogenic	0.804
NPC1	O15118-1.2	N572S	Pathogenic	0.689
NPC1	O15118-1.2	N572T	Pathogenic	0.724
NPC1	O15118-1.2	N572V	Pathogenic	0.863
NPC1	O15118-1.2	N572W	Pathogenic	0.903
NPC1	O15118-1.2	N572Y	Pathogenic	0.853
NPC1	O15118-1.2	D573A	Pathogenic	0.664
NPC1	O15118-1.2	D573C	Pathogenic	0.674
NPC1	O15118-1.2	D573E	Neutral	0.358
NPC1	O15118-1.2	D573F	Pathogenic	0.667
NPC1	O15118-1.2	D573G	Pathogenic	0.625
NPC1	O15118-1.2	D573H	Pathogenic	0.592
NPC1	O15118-1.2	D573I	Pathogenic	0.651
NPC1	O15118-1.2	D573K	Pathogenic	0.668
NPC1	O15118-1.2	D573L	Pathogenic	0.74
NPC1	O15118-1.2	D573M	Pathogenic	0.693
NPC1	O15118-1.2	D573N	Neutral	0.428
NPC1	O15118-1.2	D573P	Pathogenic	0.505
NPC1	O15118-1.2	D573Q	Pathogenic	0.52
NPC1	O15118-1.2	D573R	Pathogenic	0.761
NPC1	O15118-1.2	D573S	Neutral	0.497
NPC1	O15118-1.2	D573T	Pathogenic	0.545
NPC1	O15118-1.2	D573V	Pathogenic	0.669
NPC1	O15118-1.2	D573W	Pathogenic	0.75
NPC1	O15118-1.2	D573Y	Pathogenic	0.732
NPC1	O15118-1.2	T574A	Neutral	0.47
NPC1	O15118-1.2	T574C	Neutral	0.482
NPC1	O15118-1.2	T574D	Neutral	0.449
NPC1	O15118-1.2	T574E	Neutral	0.481
NPC1	O15118-1.2	T574F	Pathogenic	0.564
NPC1	O15118-1.2	T574G	Pathogenic	0.668
NPC1	O15118-1.2	T574H	Pathogenic	0.65
NPC1	O15118-1.2	T574I	Neutral	0.45
NPC1	O15118-1.2	T574K	Neutral	0.491
NPC1	O15118-1.2	T574L	Neutral	0.458
NPC1	O15118-1.2	T574M	Neutral	0.497
NPC1	O15118-1.2	T574N	Neutral	0.371
NPC1	O15118-1.2	T574P	Neutral	0.497
NPC1	O15118-1.2	T574Q	Pathogenic	0.523
NPC1	O15118-1.2	T574R	Pathogenic	0.51
NPC1	O15118-1.2	T574S	Neutral	0.349
NPC1	O15118-1.2	T574V	Neutral	0.376
NPC1	O15118-1.2	T574W	Pathogenic	0.567
NPC1	O15118-1.2	T574Y	Pathogenic	0.638
NPC1	O15118-1.2	E575A	Neutral	0.211
NPC1	O15118-1.2	E575C	Neutral	0.378
NPC1	O15118-1.2	E575D	Neutral	0.087
NPC1	O15118-1.2	E575F	Neutral	0.244
NPC1	O15118-1.2	E575G	Neutral	0.329
NPC1	O15118-1.2	E575H	Neutral	0.137
NPC1	O15118-1.2	E575I	Neutral	0.231
NPC1	O15118-1.2	E575K	Neutral	0.121
NPC1	O15118-1.2	E575L	Neutral	0.237
NPC1	O15118-1.2	E575M	Neutral	0.198
NPC1	O15118-1.2	E575N	Neutral	0.171
NPC1	O15118-1.2	E575P	Neutral	0.169
NPC1	O15118-1.2	E575Q	Neutral	0.074
NPC1	O15118-1.2	E575R	Neutral	0.178
NPC1	O15118-1.2	E575S	Neutral	0.165
NPC1	O15118-1.2	E575T	Neutral	0.189
NPC1	O15118-1.2	E575V	Neutral	0.188
NPC1	O15118-1.2	E575W	Neutral	0.246
NPC1	O15118-1.2	E575Y	Neutral	0.23
NPC1	O15118-1.2	K576A	Pathogenic	0.789
NPC1	O15118-1.2	K576C	Pathogenic	0.852
NPC1	O15118-1.2	K576D	Pathogenic	0.822
NPC1	O15118-1.2	K576E	Pathogenic	0.647
NPC1	O15118-1.2	K576F	Pathogenic	0.766
NPC1	O15118-1.2	K576G	Pathogenic	0.872
NPC1	O15118-1.2	K576H	Pathogenic	0.744
NPC1	O15118-1.2	K576I	Pathogenic	0.777
NPC1	O15118-1.2	K576L	Pathogenic	0.71
NPC1	O15118-1.2	K576M	Pathogenic	0.661
NPC1	O15118-1.2	K576N	Pathogenic	0.742
NPC1	O15118-1.2	K576P	Pathogenic	0.739
NPC1	O15118-1.2	K576Q	Pathogenic	0.608
NPC1	O15118-1.2	K576R	Pathogenic	0.563
NPC1	O15118-1.2	K576S	Pathogenic	0.733
NPC1	O15118-1.2	K576T	Pathogenic	0.764
NPC1	O15118-1.2	K576V	Pathogenic	0.763
NPC1	O15118-1.2	K576W	Pathogenic	0.769
NPC1	O15118-1.2	K576Y	Pathogenic	0.752
NPC1	O15118-1.2	L577A	Pathogenic	0.722
NPC1	O15118-1.2	L577C	Pathogenic	0.743
NPC1	O15118-1.2	L577D	Pathogenic	0.833
NPC1	O15118-1.2	L577E	Pathogenic	0.761
NPC1	O15118-1.2	L577F	Pathogenic	0.673
NPC1	O15118-1.2	L577G	Pathogenic	0.893
NPC1	O15118-1.2	L577H	Pathogenic	0.795
NPC1	O15118-1.2	L577I	Neutral	0.47
NPC1	O15118-1.2	L577K	Pathogenic	0.652
NPC1	O15118-1.2	L577M	Neutral	0.44
NPC1	O15118-1.2	L577N	Pathogenic	0.777
NPC1	O15118-1.2	L577P	Pathogenic	0.848
NPC1	O15118-1.2	L577Q	Pathogenic	0.707
NPC1	O15118-1.2	L577R	Pathogenic	0.669
NPC1	O15118-1.2	L577S	Pathogenic	0.766
NPC1	O15118-1.2	L577T	Pathogenic	0.685
NPC1	O15118-1.2	L577V	Pathogenic	0.563
NPC1	O15118-1.2	L577W	Pathogenic	0.819
NPC1	O15118-1.2	L577Y	Pathogenic	0.717
NPC1	O15118-1.2	Q578A	Neutral	0.209
NPC1	O15118-1.2	Q578C	Neutral	0.29
NPC1	O15118-1.2	Q578D	Neutral	0.134
NPC1	O15118-1.2	Q578E	Neutral	0.063
NPC1	O15118-1.2	Q578F	Neutral	0.23
NPC1	O15118-1.2	Q578G	Neutral	0.326
NPC1	O15118-1.2	Q578H	Neutral	0.128
NPC1	O15118-1.2	Q578I	Neutral	0.218
NPC1	O15118-1.2	Q578K	Neutral	0.088
NPC1	O15118-1.2	Q578L	Neutral	0.164
NPC1	O15118-1.2	Q578M	Neutral	0.096
NPC1	O15118-1.2	Q578N	Neutral	0.137
NPC1	O15118-1.2	Q578P	Neutral	0.167
NPC1	O15118-1.2	Q578R	Neutral	0.094
NPC1	O15118-1.2	Q578S	Neutral	0.163
NPC1	O15118-1.2	Q578T	Neutral	0.187
NPC1	O15118-1.2	Q578V	Neutral	0.186
NPC1	O15118-1.2	Q578W	Neutral	0.171
NPC1	O15118-1.2	Q578Y	Neutral	0.159
NPC1	O15118-1.2	R579A	Neutral	0.492
NPC1	O15118-1.2	R579C	Pathogenic	0.598
NPC1	O15118-1.2	R579D	Pathogenic	0.638
NPC1	O15118-1.2	R579E	Neutral	0.411
NPC1	O15118-1.2	R579F	Neutral	0.459
NPC1	O15118-1.2	R579G	Pathogenic	0.639
NPC1	O15118-1.2	R579H	Neutral	0.339
NPC1	O15118-1.2	R579I	Neutral	0.474
NPC1	O15118-1.2	R579K	Neutral	0.237
NPC1	O15118-1.2	R579L	Neutral	0.388
NPC1	O15118-1.2	R579M	Neutral	0.335
NPC1	O15118-1.2	R579N	Neutral	0.427
NPC1	O15118-1.2	R579P	Pathogenic	0.519
NPC1	O15118-1.2	R579Q	Neutral	0.286
NPC1	O15118-1.2	R579S	Pathogenic	0.511
NPC1	O15118-1.2	R579T	Neutral	0.457
NPC1	O15118-1.2	R579V	Pathogenic	0.551
NPC1	O15118-1.2	R579W	Neutral	0.424
NPC1	O15118-1.2	R579Y	Neutral	0.423
NPC1	O15118-1.2	A580C	Pathogenic	0.871
NPC1	O15118-1.2	A580D	Pathogenic	0.93
NPC1	O15118-1.2	A580E	Pathogenic	0.913
NPC1	O15118-1.2	A580F	Pathogenic	0.938
NPC1	O15118-1.2	A580G	Pathogenic	0.884
NPC1	O15118-1.2	A580H	Pathogenic	0.954
NPC1	O15118-1.2	A580I	Pathogenic	0.905
NPC1	O15118-1.2	A580K	Pathogenic	0.916
NPC1	O15118-1.2	A580L	Pathogenic	0.908
NPC1	O15118-1.2	A580M	Pathogenic	0.92
NPC1	O15118-1.2	A580N	Pathogenic	0.935
NPC1	O15118-1.2	A580P	Pathogenic	0.918
NPC1	O15118-1.2	A580Q	Pathogenic	0.925
NPC1	O15118-1.2	A580R	Pathogenic	0.921
NPC1	O15118-1.2	A580S	Pathogenic	0.826
NPC1	O15118-1.2	A580T	Pathogenic	0.897
NPC1	O15118-1.2	A580V	Pathogenic	0.875
NPC1	O15118-1.2	A580W	Pathogenic	0.957
NPC1	O15118-1.2	A580Y	Pathogenic	0.954
NPC1	O15118-1.2	Q581A	Neutral	0.48
NPC1	O15118-1.2	Q581C	Pathogenic	0.587
NPC1	O15118-1.2	Q581D	Neutral	0.35
NPC1	O15118-1.2	Q581E	Neutral	0.189
NPC1	O15118-1.2	Q581F	Pathogenic	0.51
NPC1	O15118-1.2	Q581G	Pathogenic	0.628
NPC1	O15118-1.2	Q581H	Neutral	0.339
NPC1	O15118-1.2	Q581I	Neutral	0.492
NPC1	O15118-1.2	Q581K	Neutral	0.252
NPC1	O15118-1.2	Q581L	Neutral	0.406
NPC1	O15118-1.2	Q581M	Neutral	0.269
NPC1	O15118-1.2	Q581N	Neutral	0.356
NPC1	O15118-1.2	Q581P	Neutral	0.412
NPC1	O15118-1.2	Q581R	Neutral	0.266
NPC1	O15118-1.2	Q581S	Neutral	0.404
NPC1	O15118-1.2	Q581T	Neutral	0.445
NPC1	O15118-1.2	Q581V	Neutral	0.443
NPC1	O15118-1.2	Q581W	Neutral	0.418
NPC1	O15118-1.2	Q581Y	Neutral	0.397
NPC1	O15118-1.2	A582C	Pathogenic	0.5
NPC1	O15118-1.2	A582D	Pathogenic	0.661
NPC1	O15118-1.2	A582E	Pathogenic	0.607
NPC1	O15118-1.2	A582F	Pathogenic	0.69
NPC1	O15118-1.2	A582G	Pathogenic	0.531
NPC1	O15118-1.2	A582H	Pathogenic	0.756
NPC1	O15118-1.2	A582I	Pathogenic	0.585
NPC1	O15118-1.2	A582K	Pathogenic	0.617
NPC1	O15118-1.2	A582L	Pathogenic	0.593
NPC1	O15118-1.2	A582M	Pathogenic	0.63
NPC1	O15118-1.2	A582N	Pathogenic	0.68
NPC1	O15118-1.2	A582P	Pathogenic	0.622
NPC1	O15118-1.2	A582Q	Pathogenic	0.647
NPC1	O15118-1.2	A582R	Pathogenic	0.634
NPC1	O15118-1.2	A582S	Neutral	0.413
NPC1	O15118-1.2	A582T	Pathogenic	0.562
NPC1	O15118-1.2	A582V	Pathogenic	0.51
NPC1	O15118-1.2	A582W	Pathogenic	0.769
NPC1	O15118-1.2	A582Y	Pathogenic	0.753
NPC1	O15118-1.2	W583A	Pathogenic	0.99
NPC1	O15118-1.2	W583C	Pathogenic	0.987
NPC1	O15118-1.2	W583D	Pathogenic	0.989
NPC1	O15118-1.2	W583E	Pathogenic	0.983
NPC1	O15118-1.2	W583F	Pathogenic	0.959
NPC1	O15118-1.2	W583G	Pathogenic	0.986
NPC1	O15118-1.2	W583H	Pathogenic	0.979
NPC1	O15118-1.2	W583I	Pathogenic	0.992
NPC1	O15118-1.2	W583K	Pathogenic	0.977
NPC1	O15118-1.2	W583L	Pathogenic	0.987
NPC1	O15118-1.2	W583M	Pathogenic	0.978
NPC1	O15118-1.2	W583N	Pathogenic	0.989
NPC1	O15118-1.2	W583P	Pathogenic	0.993
NPC1	O15118-1.2	W583Q	Pathogenic	0.977
NPC1	O15118-1.2	W583R	Pathogenic	0.976
NPC1	O15118-1.2	W583S	Pathogenic	0.989
NPC1	O15118-1.2	W583T	Pathogenic	0.983
NPC1	O15118-1.2	W583V	Pathogenic	0.991
NPC1	O15118-1.2	W583Y	Pathogenic	0.921
NPC1	O15118-1.2	E584A	Pathogenic	0.966
NPC1	O15118-1.2	E584C	Pathogenic	0.985
NPC1	O15118-1.2	E584D	Pathogenic	0.909
NPC1	O15118-1.2	E584F	Pathogenic	0.971
NPC1	O15118-1.2	E584G	Pathogenic	0.981
NPC1	O15118-1.2	E584H	Pathogenic	0.943
NPC1	O15118-1.2	E584I	Pathogenic	0.969
NPC1	O15118-1.2	E584K	Pathogenic	0.935
NPC1	O15118-1.2	E584L	Pathogenic	0.97
NPC1	O15118-1.2	E584M	Pathogenic	0.963
NPC1	O15118-1.2	E584N	Pathogenic	0.956
NPC1	O15118-1.2	E584P	Pathogenic	0.955
NPC1	O15118-1.2	E584Q	Pathogenic	0.894
NPC1	O15118-1.2	E584R	Pathogenic	0.958
NPC1	O15118-1.2	E584S	Pathogenic	0.954
NPC1	O15118-1.2	E584T	Pathogenic	0.961
NPC1	O15118-1.2	E584V	Pathogenic	0.96
NPC1	O15118-1.2	E584W	Pathogenic	0.972
NPC1	O15118-1.2	E584Y	Pathogenic	0.969
NPC1	O15118-1.2	K585A	Pathogenic	0.655
NPC1	O15118-1.2	K585C	Pathogenic	0.745
NPC1	O15118-1.2	K585D	Pathogenic	0.702
NPC1	O15118-1.2	K585E	Neutral	0.483
NPC1	O15118-1.2	K585F	Pathogenic	0.625
NPC1	O15118-1.2	K585G	Pathogenic	0.776
NPC1	O15118-1.2	K585H	Pathogenic	0.597
NPC1	O15118-1.2	K585I	Pathogenic	0.639
NPC1	O15118-1.2	K585L	Pathogenic	0.555
NPC1	O15118-1.2	K585M	Neutral	0.498
NPC1	O15118-1.2	K585N	Pathogenic	0.595
NPC1	O15118-1.2	K585P	Pathogenic	0.591
NPC1	O15118-1.2	K585Q	Neutral	0.441
NPC1	O15118-1.2	K585R	Neutral	0.396
NPC1	O15118-1.2	K585S	Pathogenic	0.583
NPC1	O15118-1.2	K585T	Pathogenic	0.623
NPC1	O15118-1.2	K585V	Pathogenic	0.621
NPC1	O15118-1.2	K585W	Pathogenic	0.629
NPC1	O15118-1.2	K585Y	Pathogenic	0.607
NPC1	O15118-1.2	E586A	Pathogenic	0.56
NPC1	O15118-1.2	E586C	Pathogenic	0.743
NPC1	O15118-1.2	E586D	Neutral	0.312
NPC1	O15118-1.2	E586F	Pathogenic	0.605
NPC1	O15118-1.2	E586G	Pathogenic	0.7
NPC1	O15118-1.2	E586H	Neutral	0.429
NPC1	O15118-1.2	E586I	Pathogenic	0.587
NPC1	O15118-1.2	E586K	Neutral	0.394
NPC1	O15118-1.2	E586L	Pathogenic	0.596
NPC1	O15118-1.2	E586M	Pathogenic	0.539
NPC1	O15118-1.2	E586N	Neutral	0.496
NPC1	O15118-1.2	E586P	Neutral	0.492
NPC1	O15118-1.2	E586Q	Neutral	0.276
NPC1	O15118-1.2	E586R	Pathogenic	0.508
NPC1	O15118-1.2	E586S	Neutral	0.484
NPC1	O15118-1.2	E586T	Pathogenic	0.525
NPC1	O15118-1.2	E586V	Pathogenic	0.524
NPC1	O15118-1.2	E586W	Pathogenic	0.608
NPC1	O15118-1.2	E586Y	Pathogenic	0.587
NPC1	O15118-1.2	F587A	Pathogenic	0.921
NPC1	O15118-1.2	F587C	Pathogenic	0.929
NPC1	O15118-1.2	F587D	Pathogenic	0.912
NPC1	O15118-1.2	F587E	Pathogenic	0.907
NPC1	O15118-1.2	F587G	Pathogenic	0.946
NPC1	O15118-1.2	F587H	Pathogenic	0.846
NPC1	O15118-1.2	F587I	Pathogenic	0.861
NPC1	O15118-1.2	F587K	Pathogenic	0.881
NPC1	O15118-1.2	F587L	Pathogenic	0.858
NPC1	O15118-1.2	F587M	Pathogenic	0.838
NPC1	O15118-1.2	F587N	Pathogenic	0.914
NPC1	O15118-1.2	F587P	Pathogenic	0.962
NPC1	O15118-1.2	F587Q	Pathogenic	0.915
NPC1	O15118-1.2	F587R	Pathogenic	0.888
NPC1	O15118-1.2	F587S	Pathogenic	0.909
NPC1	O15118-1.2	F587T	Pathogenic	0.907
NPC1	O15118-1.2	F587V	Pathogenic	0.895
NPC1	O15118-1.2	F587W	Pathogenic	0.801
NPC1	O15118-1.2	F587Y	Pathogenic	0.591
NPC1	O15118-1.2	I588A	Pathogenic	0.787
NPC1	O15118-1.2	I588C	Pathogenic	0.805
NPC1	O15118-1.2	I588D	Pathogenic	0.828
NPC1	O15118-1.2	I588E	Pathogenic	0.819
NPC1	O15118-1.2	I588F	Pathogenic	0.757
NPC1	O15118-1.2	I588G	Pathogenic	0.922
NPC1	O15118-1.2	I588H	Pathogenic	0.847
NPC1	O15118-1.2	I588K	Pathogenic	0.797
NPC1	O15118-1.2	I588L	Pathogenic	0.566
NPC1	O15118-1.2	I588M	Pathogenic	0.622
NPC1	O15118-1.2	I588N	Pathogenic	0.832
NPC1	O15118-1.2	I588P	Pathogenic	0.889
NPC1	O15118-1.2	I588Q	Pathogenic	0.835
NPC1	O15118-1.2	I588R	Pathogenic	0.809
NPC1	O15118-1.2	I588S	Pathogenic	0.824
NPC1	O15118-1.2	I588T	Pathogenic	0.756
NPC1	O15118-1.2	I588V	Neutral	0.459
NPC1	O15118-1.2	I588W	Pathogenic	0.91
NPC1	O15118-1.2	I588Y	Pathogenic	0.783
NPC1	O15118-1.2	N589A	Neutral	0.459
NPC1	O15118-1.2	N589C	Neutral	0.471
NPC1	O15118-1.2	N589D	Neutral	0.228
NPC1	O15118-1.2	N589E	Neutral	0.323
NPC1	O15118-1.2	N589F	Neutral	0.448
NPC1	O15118-1.2	N589G	Neutral	0.328
NPC1	O15118-1.2	N589H	Neutral	0.213
NPC1	O15118-1.2	N589I	Neutral	0.43
NPC1	O15118-1.2	N589K	Neutral	0.332
NPC1	O15118-1.2	N589L	Neutral	0.439
NPC1	O15118-1.2	N589M	Neutral	0.383
NPC1	O15118-1.2	N589P	Neutral	0.392
NPC1	O15118-1.2	N589Q	Neutral	0.305
NPC1	O15118-1.2	N589R	Neutral	0.348
NPC1	O15118-1.2	N589S	Neutral	0.224
NPC1	O15118-1.2	N589T	Neutral	0.255
NPC1	O15118-1.2	N589V	Neutral	0.45
NPC1	O15118-1.2	N589W	Pathogenic	0.548
NPC1	O15118-1.2	N589Y	Neutral	0.43
NPC1	O15118-1.2	F590A	Pathogenic	0.845
NPC1	O15118-1.2	F590C	Pathogenic	0.858
NPC1	O15118-1.2	F590D	Pathogenic	0.829
NPC1	O15118-1.2	F590E	Pathogenic	0.819
NPC1	O15118-1.2	F590G	Pathogenic	0.89
NPC1	O15118-1.2	F590H	Pathogenic	0.719
NPC1	O15118-1.2	F590I	Pathogenic	0.744
NPC1	O15118-1.2	F590K	Pathogenic	0.775
NPC1	O15118-1.2	F590L	Pathogenic	0.739
NPC1	O15118-1.2	F590M	Pathogenic	0.708
NPC1	O15118-1.2	F590N	Pathogenic	0.832
NPC1	O15118-1.2	F590P	Pathogenic	0.921
NPC1	O15118-1.2	F590Q	Pathogenic	0.835
NPC1	O15118-1.2	F590R	Pathogenic	0.788
NPC1	O15118-1.2	F590S	Pathogenic	0.824
NPC1	O15118-1.2	F590T	Pathogenic	0.82
NPC1	O15118-1.2	F590V	Pathogenic	0.799
NPC1	O15118-1.2	F590W	Pathogenic	0.653
NPC1	O15118-1.2	F590Y	Neutral	0.403
NPC1	O15118-1.2	V591A	Pathogenic	0.559
NPC1	O15118-1.2	V591C	Pathogenic	0.675
NPC1	O15118-1.2	V591D	Pathogenic	0.709
NPC1	O15118-1.2	V591E	Pathogenic	0.619
NPC1	O15118-1.2	V591F	Pathogenic	0.665
NPC1	O15118-1.2	V591G	Pathogenic	0.803
NPC1	O15118-1.2	V591H	Pathogenic	0.766
NPC1	O15118-1.2	V591I	Neutral	0.283
NPC1	O15118-1.2	V591K	Pathogenic	0.629
NPC1	O15118-1.2	V591L	Neutral	0.469
NPC1	O15118-1.2	V591M	Pathogenic	0.508
NPC1	O15118-1.2	V591N	Pathogenic	0.714
NPC1	O15118-1.2	V591P	Pathogenic	0.732
NPC1	O15118-1.2	V591Q	Pathogenic	0.658
NPC1	O15118-1.2	V591R	Pathogenic	0.728
NPC1	O15118-1.2	V591S	Pathogenic	0.702
NPC1	O15118-1.2	V591T	Pathogenic	0.515
NPC1	O15118-1.2	V591W	Pathogenic	0.813
NPC1	O15118-1.2	V591Y	Pathogenic	0.695
NPC1	O15118-1.2	K592A	Pathogenic	0.793
NPC1	O15118-1.2	K592C	Pathogenic	0.855
NPC1	O15118-1.2	K592D	Pathogenic	0.826
NPC1	O15118-1.2	K592E	Pathogenic	0.653
NPC1	O15118-1.2	K592F	Pathogenic	0.771
NPC1	O15118-1.2	K592G	Pathogenic	0.875
NPC1	O15118-1.2	K592H	Pathogenic	0.749
NPC1	O15118-1.2	K592I	Pathogenic	0.781
NPC1	O15118-1.2	K592L	Pathogenic	0.715
NPC1	O15118-1.2	K592M	Pathogenic	0.666
NPC1	O15118-1.2	K592N	Pathogenic	0.747
NPC1	O15118-1.2	K592P	Pathogenic	0.744
NPC1	O15118-1.2	K592Q	Pathogenic	0.614
NPC1	O15118-1.2	K592R	Pathogenic	0.57
NPC1	O15118-1.2	K592S	Pathogenic	0.738
NPC1	O15118-1.2	K592T	Pathogenic	0.769
NPC1	O15118-1.2	K592V	Pathogenic	0.768
NPC1	O15118-1.2	K592W	Pathogenic	0.773
NPC1	O15118-1.2	K592Y	Pathogenic	0.757
NPC1	O15118-1.2	N593A	Pathogenic	0.819
NPC1	O15118-1.2	N593C	Pathogenic	0.826
NPC1	O15118-1.2	N593D	Pathogenic	0.611
NPC1	O15118-1.2	N593E	Pathogenic	0.717
NPC1	O15118-1.2	N593F	Pathogenic	0.812
NPC1	O15118-1.2	N593G	Pathogenic	0.722
NPC1	O15118-1.2	N593H	Pathogenic	0.591
NPC1	O15118-1.2	N593I	Pathogenic	0.801
NPC1	O15118-1.2	N593K	Pathogenic	0.725
NPC1	O15118-1.2	N593L	Pathogenic	0.806
NPC1	O15118-1.2	N593M	Pathogenic	0.768
NPC1	O15118-1.2	N593P	Pathogenic	0.774
NPC1	O15118-1.2	N593Q	Pathogenic	0.7
NPC1	O15118-1.2	N593R	Pathogenic	0.739
NPC1	O15118-1.2	N593S	Pathogenic	0.606
NPC1	O15118-1.2	N593T	Pathogenic	0.645
NPC1	O15118-1.2	N593V	Pathogenic	0.813
NPC1	O15118-1.2	N593W	Pathogenic	0.866
NPC1	O15118-1.2	N593Y	Pathogenic	0.8
NPC1	O15118-1.2	Y594A	Pathogenic	0.922
NPC1	O15118-1.2	Y594C	Pathogenic	0.928
NPC1	O15118-1.2	Y594D	Pathogenic	0.913
NPC1	O15118-1.2	Y594E	Pathogenic	0.869
NPC1	O15118-1.2	Y594F	Pathogenic	0.516
NPC1	O15118-1.2	Y594G	Pathogenic	0.946
NPC1	O15118-1.2	Y594H	Pathogenic	0.635
NPC1	O15118-1.2	Y594I	Pathogenic	0.841
NPC1	O15118-1.2	Y594K	Pathogenic	0.835
NPC1	O15118-1.2	Y594L	Pathogenic	0.846
NPC1	O15118-1.2	Y594M	Pathogenic	0.865
NPC1	O15118-1.2	Y594N	Pathogenic	0.879
NPC1	O15118-1.2	Y594P	Pathogenic	0.945
NPC1	O15118-1.2	Y594Q	Pathogenic	0.834
NPC1	O15118-1.2	Y594R	Pathogenic	0.835
NPC1	O15118-1.2	Y594S	Pathogenic	0.91
NPC1	O15118-1.2	Y594T	Pathogenic	0.908
NPC1	O15118-1.2	Y594V	Pathogenic	0.879
NPC1	O15118-1.2	Y594W	Pathogenic	0.597
NPC1	O15118-1.2	K595A	Neutral	0.36
NPC1	O15118-1.2	K595C	Neutral	0.464
NPC1	O15118-1.2	K595D	Neutral	0.41
NPC1	O15118-1.2	K595E	Neutral	0.216
NPC1	O15118-1.2	K595F	Neutral	0.33
NPC1	O15118-1.2	K595G	Pathogenic	0.507
NPC1	O15118-1.2	K595H	Neutral	0.305
NPC1	O15118-1.2	K595I	Neutral	0.344
NPC1	O15118-1.2	K595L	Neutral	0.269
NPC1	O15118-1.2	K595M	Neutral	0.227
NPC1	O15118-1.2	K595N	Neutral	0.303
NPC1	O15118-1.2	K595P	Neutral	0.299
NPC1	O15118-1.2	K595Q	Neutral	0.189
NPC1	O15118-1.2	K595R	Neutral	0.163
NPC1	O15118-1.2	K595S	Neutral	0.293
NPC1	O15118-1.2	K595T	Neutral	0.328
NPC1	O15118-1.2	K595V	Neutral	0.327
NPC1	O15118-1.2	K595W	Neutral	0.334
NPC1	O15118-1.2	K595Y	Neutral	0.314
NPC1	O15118-1.2	N596A	Pathogenic	0.706
NPC1	O15118-1.2	N596C	Pathogenic	0.715
NPC1	O15118-1.2	N596D	Neutral	0.455
NPC1	O15118-1.2	N596E	Pathogenic	0.574
NPC1	O15118-1.2	N596F	Pathogenic	0.696
NPC1	O15118-1.2	N596G	Pathogenic	0.579
NPC1	O15118-1.2	N596H	Neutral	0.434
NPC1	O15118-1.2	N596I	Pathogenic	0.681
NPC1	O15118-1.2	N596K	Pathogenic	0.583
NPC1	O15118-1.2	N596L	Pathogenic	0.688
NPC1	O15118-1.2	N596M	Pathogenic	0.637
NPC1	O15118-1.2	N596P	Pathogenic	0.646
NPC1	O15118-1.2	N596Q	Pathogenic	0.553
NPC1	O15118-1.2	N596R	Pathogenic	0.601
NPC1	O15118-1.2	N596S	Neutral	0.449
NPC1	O15118-1.2	N596T	Neutral	0.491
NPC1	O15118-1.2	N596V	Pathogenic	0.698
NPC1	O15118-1.2	N596W	Pathogenic	0.774
NPC1	O15118-1.2	N596Y	Pathogenic	0.68
NPC1	O15118-1.2	P597A	Pathogenic	0.787
NPC1	O15118-1.2	P597C	Pathogenic	0.882
NPC1	O15118-1.2	P597D	Pathogenic	0.694
NPC1	O15118-1.2	P597E	Pathogenic	0.725
NPC1	O15118-1.2	P597F	Pathogenic	0.915
NPC1	O15118-1.2	P597G	Pathogenic	0.847
NPC1	O15118-1.2	P597H	Pathogenic	0.841
NPC1	O15118-1.2	P597I	Pathogenic	0.872
NPC1	O15118-1.2	P597K	Pathogenic	0.733
NPC1	O15118-1.2	P597L	Pathogenic	0.876
NPC1	O15118-1.2	P597M	Pathogenic	0.849
NPC1	O15118-1.2	P597N	Pathogenic	0.784
NPC1	O15118-1.2	P597Q	Pathogenic	0.758
NPC1	O15118-1.2	P597R	Pathogenic	0.813
NPC1	O15118-1.2	P597S	Pathogenic	0.761
NPC1	O15118-1.2	P597T	Pathogenic	0.763
NPC1	O15118-1.2	P597V	Pathogenic	0.834
NPC1	O15118-1.2	P597W	Pathogenic	0.917
NPC1	O15118-1.2	P597Y	Pathogenic	0.909
NPC1	O15118-1.2	N598A	Pathogenic	0.791
NPC1	O15118-1.2	N598C	Pathogenic	0.799
NPC1	O15118-1.2	N598D	Pathogenic	0.569
NPC1	O15118-1.2	N598E	Pathogenic	0.68
NPC1	O15118-1.2	N598F	Pathogenic	0.784
NPC1	O15118-1.2	N598G	Pathogenic	0.685
NPC1	O15118-1.2	N598H	Pathogenic	0.548
NPC1	O15118-1.2	N598I	Pathogenic	0.771
NPC1	O15118-1.2	N598K	Pathogenic	0.689
NPC1	O15118-1.2	N598L	Pathogenic	0.777
NPC1	O15118-1.2	N598M	Pathogenic	0.735
NPC1	O15118-1.2	N598P	Pathogenic	0.742
NPC1	O15118-1.2	N598Q	Pathogenic	0.661
NPC1	O15118-1.2	N598R	Pathogenic	0.704
NPC1	O15118-1.2	N598S	Pathogenic	0.563
NPC1	O15118-1.2	N598T	Pathogenic	0.604
NPC1	O15118-1.2	N598V	Pathogenic	0.785
NPC1	O15118-1.2	N598W	Pathogenic	0.844
NPC1	O15118-1.2	N598Y	Pathogenic	0.771
NPC1	O15118-1.2	L599A	Pathogenic	0.675
NPC1	O15118-1.2	L599C	Pathogenic	0.698
NPC1	O15118-1.2	L599D	Pathogenic	0.8
NPC1	O15118-1.2	L599E	Pathogenic	0.718
NPC1	O15118-1.2	L599F	Pathogenic	0.623
NPC1	O15118-1.2	L599G	Pathogenic	0.87
NPC1	O15118-1.2	L599H	Pathogenic	0.757
NPC1	O15118-1.2	L599I	Neutral	0.415
NPC1	O15118-1.2	L599K	Pathogenic	0.6
NPC1	O15118-1.2	L599M	Neutral	0.386
NPC1	O15118-1.2	L599N	Pathogenic	0.736
NPC1	O15118-1.2	L599P	Pathogenic	0.818
NPC1	O15118-1.2	L599Q	Pathogenic	0.659
NPC1	O15118-1.2	L599R	Pathogenic	0.618
NPC1	O15118-1.2	L599S	Pathogenic	0.724
NPC1	O15118-1.2	L599T	Pathogenic	0.636
NPC1	O15118-1.2	L599V	Pathogenic	0.508
NPC1	O15118-1.2	L599W	Pathogenic	0.784
NPC1	O15118-1.2	L599Y	Pathogenic	0.669
NPC1	O15118-1.2	T600A	Pathogenic	0.664
NPC1	O15118-1.2	T600C	Pathogenic	0.674
NPC1	O15118-1.2	T600D	Pathogenic	0.645
NPC1	O15118-1.2	T600E	Pathogenic	0.674
NPC1	O15118-1.2	T600F	Pathogenic	0.742
NPC1	O15118-1.2	T600G	Pathogenic	0.818
NPC1	O15118-1.2	T600H	Pathogenic	0.806
NPC1	O15118-1.2	T600I	Pathogenic	0.646
NPC1	O15118-1.2	T600K	Pathogenic	0.683
NPC1	O15118-1.2	T600L	Pathogenic	0.654
NPC1	O15118-1.2	T600M	Pathogenic	0.688
NPC1	O15118-1.2	T600N	Pathogenic	0.568
NPC1	O15118-1.2	T600P	Pathogenic	0.688
NPC1	O15118-1.2	T600Q	Pathogenic	0.71
NPC1	O15118-1.2	T600R	Pathogenic	0.699
NPC1	O15118-1.2	T600S	Pathogenic	0.545
NPC1	O15118-1.2	T600V	Pathogenic	0.573
NPC1	O15118-1.2	T600W	Pathogenic	0.745
NPC1	O15118-1.2	T600Y	Pathogenic	0.797
NPC1	O15118-1.2	I601A	Pathogenic	0.828
NPC1	O15118-1.2	I601C	Pathogenic	0.843
NPC1	O15118-1.2	I601D	Pathogenic	0.863
NPC1	O15118-1.2	I601E	Pathogenic	0.855
NPC1	O15118-1.2	I601F	Pathogenic	0.802
NPC1	O15118-1.2	I601G	Pathogenic	0.94
NPC1	O15118-1.2	I601H	Pathogenic	0.878
NPC1	O15118-1.2	I601K	Pathogenic	0.837
NPC1	O15118-1.2	I601L	Pathogenic	0.63
NPC1	O15118-1.2	I601M	Pathogenic	0.682
NPC1	O15118-1.2	I601N	Pathogenic	0.866
NPC1	O15118-1.2	I601P	Pathogenic	0.912
NPC1	O15118-1.2	I601Q	Pathogenic	0.868
NPC1	O15118-1.2	I601R	Pathogenic	0.847
NPC1	O15118-1.2	I601S	Pathogenic	0.859
NPC1	O15118-1.2	I601T	Pathogenic	0.802
NPC1	O15118-1.2	I601V	Pathogenic	0.526
NPC1	O15118-1.2	I601W	Pathogenic	0.93
NPC1	O15118-1.2	I601Y	Pathogenic	0.825
NPC1	O15118-1.2	S602A	Pathogenic	0.638
NPC1	O15118-1.2	S602C	Pathogenic	0.761
NPC1	O15118-1.2	S602D	Pathogenic	0.711
NPC1	O15118-1.2	S602E	Pathogenic	0.741
NPC1	O15118-1.2	S602F	Pathogenic	0.828
NPC1	O15118-1.2	S602G	Pathogenic	0.763
NPC1	O15118-1.2	S602H	Pathogenic	0.837
NPC1	O15118-1.2	S602I	Pathogenic	0.818
NPC1	O15118-1.2	S602K	Pathogenic	0.749
NPC1	O15118-1.2	S602L	Pathogenic	0.823
NPC1	O15118-1.2	S602M	Pathogenic	0.787
NPC1	O15118-1.2	S602N	Pathogenic	0.645
NPC1	O15118-1.2	S602P	Pathogenic	0.781
NPC1	O15118-1.2	S602Q	Pathogenic	0.772
NPC1	O15118-1.2	S602R	Pathogenic	0.825
NPC1	O15118-1.2	S602T	Pathogenic	0.662
NPC1	O15118-1.2	S602V	Pathogenic	0.829
NPC1	O15118-1.2	S602W	Pathogenic	0.878
NPC1	O15118-1.2	S602Y	Pathogenic	0.868
NPC1	O15118-1.2	F603A	Pathogenic	0.939
NPC1	O15118-1.2	F603C	Pathogenic	0.945
NPC1	O15118-1.2	F603D	Pathogenic	0.932
NPC1	O15118-1.2	F603E	Pathogenic	0.927
NPC1	O15118-1.2	F603G	Pathogenic	0.958
NPC1	O15118-1.2	F603H	Pathogenic	0.878
NPC1	O15118-1.2	F603I	Pathogenic	0.891
NPC1	O15118-1.2	F603K	Pathogenic	0.906
NPC1	O15118-1.2	F603L	Pathogenic	0.888
NPC1	O15118-1.2	F603M	Pathogenic	0.872
NPC1	O15118-1.2	F603N	Pathogenic	0.933
NPC1	O15118-1.2	F603P	Pathogenic	0.971
NPC1	O15118-1.2	F603Q	Pathogenic	0.934
NPC1	O15118-1.2	F603R	Pathogenic	0.913
NPC1	O15118-1.2	F603S	Pathogenic	0.929
NPC1	O15118-1.2	F603T	Pathogenic	0.928
NPC1	O15118-1.2	F603V	Pathogenic	0.918
NPC1	O15118-1.2	F603W	Pathogenic	0.841
NPC1	O15118-1.2	F603Y	Pathogenic	0.655
NPC1	O15118-1.2	T604A	Pathogenic	0.506
NPC1	O15118-1.2	T604C	Pathogenic	0.518
NPC1	O15118-1.2	T604D	Neutral	0.485
NPC1	O15118-1.2	T604E	Pathogenic	0.517
NPC1	O15118-1.2	T604F	Pathogenic	0.599
NPC1	O15118-1.2	T604G	Pathogenic	0.699
NPC1	O15118-1.2	T604H	Pathogenic	0.683
NPC1	O15118-1.2	T604I	Neutral	0.486
NPC1	O15118-1.2	T604K	Pathogenic	0.527
NPC1	O15118-1.2	T604L	Neutral	0.494
NPC1	O15118-1.2	T604M	Pathogenic	0.533
NPC1	O15118-1.2	T604N	Neutral	0.405
NPC1	O15118-1.2	T604P	Pathogenic	0.534
NPC1	O15118-1.2	T604Q	Pathogenic	0.559
NPC1	O15118-1.2	T604R	Pathogenic	0.546
NPC1	O15118-1.2	T604S	Neutral	0.383
NPC1	O15118-1.2	T604V	Neutral	0.41
NPC1	O15118-1.2	T604W	Pathogenic	0.603
NPC1	O15118-1.2	T604Y	Pathogenic	0.671
NPC1	O15118-1.2	A605C	Pathogenic	0.708
NPC1	O15118-1.2	A605D	Pathogenic	0.825
NPC1	O15118-1.2	A605E	Pathogenic	0.789
NPC1	O15118-1.2	A605F	Pathogenic	0.844
NPC1	O15118-1.2	A605G	Pathogenic	0.733
NPC1	O15118-1.2	A605H	Pathogenic	0.883
NPC1	O15118-1.2	A605I	Pathogenic	0.774
NPC1	O15118-1.2	A605K	Pathogenic	0.796
NPC1	O15118-1.2	A605L	Pathogenic	0.78
NPC1	O15118-1.2	A605M	Pathogenic	0.805
NPC1	O15118-1.2	A605N	Pathogenic	0.838
NPC1	O15118-1.2	A605P	Pathogenic	0.8
NPC1	O15118-1.2	A605Q	Pathogenic	0.816
NPC1	O15118-1.2	A605R	Pathogenic	0.808
NPC1	O15118-1.2	A605S	Pathogenic	0.63
NPC1	O15118-1.2	A605T	Pathogenic	0.757
NPC1	O15118-1.2	A605V	Pathogenic	0.716
NPC1	O15118-1.2	A605W	Pathogenic	0.89
NPC1	O15118-1.2	A605Y	Pathogenic	0.881
NPC1	O15118-1.2	E606A	Pathogenic	0.958
NPC1	O15118-1.2	E606C	Pathogenic	0.981
NPC1	O15118-1.2	E606D	Pathogenic	0.891
NPC1	O15118-1.2	E606F	Pathogenic	0.965
NPC1	O15118-1.2	E606G	Pathogenic	0.977
NPC1	O15118-1.2	E606H	Pathogenic	0.931
NPC1	O15118-1.2	E606I	Pathogenic	0.962
NPC1	O15118-1.2	E606K	Pathogenic	0.921
NPC1	O15118-1.2	E606L	Pathogenic	0.964
NPC1	O15118-1.2	E606M	Pathogenic	0.955
NPC1	O15118-1.2	E606N	Pathogenic	0.946
NPC1	O15118-1.2	E606P	Pathogenic	0.946
NPC1	O15118-1.2	E606Q	Pathogenic	0.873
NPC1	O15118-1.2	E606R	Pathogenic	0.949
NPC1	O15118-1.2	E606S	Pathogenic	0.944
NPC1	O15118-1.2	E606T	Pathogenic	0.952
NPC1	O15118-1.2	E606V	Pathogenic	0.952
NPC1	O15118-1.2	E606W	Pathogenic	0.965
NPC1	O15118-1.2	E606Y	Pathogenic	0.962
NPC1	O15118-1.2	R607A	Pathogenic	0.959
NPC1	O15118-1.2	R607C	Pathogenic	0.973
NPC1	O15118-1.2	R607D	Pathogenic	0.977
NPC1	O15118-1.2	R607E	Pathogenic	0.944
NPC1	O15118-1.2	R607F	Pathogenic	0.954
NPC1	O15118-1.2	R607G	Pathogenic	0.977
NPC1	O15118-1.2	R607H	Pathogenic	0.926
NPC1	O15118-1.2	R607I	Pathogenic	0.956
NPC1	O15118-1.2	R607K	Pathogenic	0.883
NPC1	O15118-1.2	R607L	Pathogenic	0.939
NPC1	O15118-1.2	R607M	Pathogenic	0.924
NPC1	O15118-1.2	R607N	Pathogenic	0.948
NPC1	O15118-1.2	R607P	Pathogenic	0.963
NPC1	O15118-1.2	R607Q	Pathogenic	0.907
NPC1	O15118-1.2	R607S	Pathogenic	0.962
NPC1	O15118-1.2	R607T	Pathogenic	0.953
NPC1	O15118-1.2	R607V	Pathogenic	0.968
NPC1	O15118-1.2	R607W	Pathogenic	0.947
NPC1	O15118-1.2	R607Y	Pathogenic	0.947
NPC1	O15118-1.2	S608A	Pathogenic	0.899
NPC1	O15118-1.2	S608C	Pathogenic	0.941
NPC1	O15118-1.2	S608D	Pathogenic	0.925
NPC1	O15118-1.2	S608E	Pathogenic	0.935
NPC1	O15118-1.2	S608F	Pathogenic	0.96
NPC1	O15118-1.2	S608G	Pathogenic	0.942
NPC1	O15118-1.2	S608H	Pathogenic	0.963
NPC1	O15118-1.2	S608I	Pathogenic	0.958
NPC1	O15118-1.2	S608K	Pathogenic	0.937
NPC1	O15118-1.2	S608L	Pathogenic	0.959
NPC1	O15118-1.2	S608M	Pathogenic	0.949
NPC1	O15118-1.2	S608N	Pathogenic	0.902
NPC1	O15118-1.2	S608P	Pathogenic	0.947
NPC1	O15118-1.2	S608Q	Pathogenic	0.945
NPC1	O15118-1.2	S608R	Pathogenic	0.96
NPC1	O15118-1.2	S608T	Pathogenic	0.908
NPC1	O15118-1.2	S608V	Pathogenic	0.961
NPC1	O15118-1.2	S608W	Pathogenic	0.973
NPC1	O15118-1.2	S608Y	Pathogenic	0.971
NPC1	O15118-1.2	I609A	Pathogenic	0.903
NPC1	O15118-1.2	I609C	Pathogenic	0.912
NPC1	O15118-1.2	I609D	Pathogenic	0.924
NPC1	O15118-1.2	I609E	Pathogenic	0.919
NPC1	O15118-1.2	I609F	Pathogenic	0.886
NPC1	O15118-1.2	I609G	Pathogenic	0.968
NPC1	O15118-1.2	I609H	Pathogenic	0.933
NPC1	O15118-1.2	I609K	Pathogenic	0.908
NPC1	O15118-1.2	I609L	Pathogenic	0.766
NPC1	O15118-1.2	I609M	Pathogenic	0.805
NPC1	O15118-1.2	I609N	Pathogenic	0.926
NPC1	O15118-1.2	I609P	Pathogenic	0.952
NPC1	O15118-1.2	I609Q	Pathogenic	0.927
NPC1	O15118-1.2	I609R	Pathogenic	0.914
NPC1	O15118-1.2	I609S	Pathogenic	0.921
NPC1	O15118-1.2	I609T	Pathogenic	0.886
NPC1	O15118-1.2	I609V	Pathogenic	0.68
NPC1	O15118-1.2	I609W	Pathogenic	0.962
NPC1	O15118-1.2	I609Y	Pathogenic	0.9
NPC1	O15118-1.2	E610A	Pathogenic	0.932
NPC1	O15118-1.2	E610C	Pathogenic	0.969
NPC1	O15118-1.2	E610D	Pathogenic	0.831
NPC1	O15118-1.2	E610F	Pathogenic	0.943
NPC1	O15118-1.2	E610G	Pathogenic	0.962
NPC1	O15118-1.2	E610H	Pathogenic	0.89
NPC1	O15118-1.2	E610I	Pathogenic	0.939
NPC1	O15118-1.2	E610K	Pathogenic	0.875
NPC1	O15118-1.2	E610L	Pathogenic	0.941
NPC1	O15118-1.2	E610M	Pathogenic	0.927
NPC1	O15118-1.2	E610N	Pathogenic	0.914
NPC1	O15118-1.2	E610P	Pathogenic	0.913
NPC1	O15118-1.2	E610Q	Pathogenic	0.805
NPC1	O15118-1.2	E610R	Pathogenic	0.918
NPC1	O15118-1.2	E610S	Pathogenic	0.91
NPC1	O15118-1.2	E610T	Pathogenic	0.923
NPC1	O15118-1.2	E610V	Pathogenic	0.922
NPC1	O15118-1.2	E610W	Pathogenic	0.944
NPC1	O15118-1.2	E610Y	Pathogenic	0.939
NPC1	O15118-1.2	D611A	Pathogenic	0.966
NPC1	O15118-1.2	D611C	Pathogenic	0.968
NPC1	O15118-1.2	D611E	Pathogenic	0.89
NPC1	O15118-1.2	D611F	Pathogenic	0.967
NPC1	O15118-1.2	D611G	Pathogenic	0.96
NPC1	O15118-1.2	D611H	Pathogenic	0.955
NPC1	O15118-1.2	D611I	Pathogenic	0.964
NPC1	O15118-1.2	D611K	Pathogenic	0.967
NPC1	O15118-1.2	D611L	Pathogenic	0.976
NPC1	O15118-1.2	D611M	Pathogenic	0.97
NPC1	O15118-1.2	D611N	Pathogenic	0.916
NPC1	O15118-1.2	D611P	Pathogenic	0.937
NPC1	O15118-1.2	D611Q	Pathogenic	0.94
NPC1	O15118-1.2	D611R	Pathogenic	0.979
NPC1	O15118-1.2	D611S	Pathogenic	0.935
NPC1	O15118-1.2	D611T	Pathogenic	0.945
NPC1	O15118-1.2	D611V	Pathogenic	0.967
NPC1	O15118-1.2	D611W	Pathogenic	0.977
NPC1	O15118-1.2	D611Y	Pathogenic	0.975
NPC1	O15118-1.2	E612A	Pathogenic	0.965
NPC1	O15118-1.2	E612C	Pathogenic	0.984
NPC1	O15118-1.2	E612D	Pathogenic	0.908
NPC1	O15118-1.2	E612F	Pathogenic	0.971
NPC1	O15118-1.2	E612G	Pathogenic	0.981
NPC1	O15118-1.2	E612H	Pathogenic	0.942
NPC1	O15118-1.2	E612I	Pathogenic	0.969
NPC1	O15118-1.2	E612K	Pathogenic	0.934
NPC1	O15118-1.2	E612L	Pathogenic	0.97
NPC1	O15118-1.2	E612M	Pathogenic	0.962
NPC1	O15118-1.2	E612N	Pathogenic	0.955
NPC1	O15118-1.2	E612P	Pathogenic	0.955
NPC1	O15118-1.2	E612Q	Pathogenic	0.892
NPC1	O15118-1.2	E612R	Pathogenic	0.957
NPC1	O15118-1.2	E612S	Pathogenic	0.953
NPC1	O15118-1.2	E612T	Pathogenic	0.96
NPC1	O15118-1.2	E612V	Pathogenic	0.96
NPC1	O15118-1.2	E612W	Pathogenic	0.971
NPC1	O15118-1.2	E612Y	Pathogenic	0.969
NPC1	O15118-1.2	L613A	Pathogenic	0.809
NPC1	O15118-1.2	L613C	Pathogenic	0.825
NPC1	O15118-1.2	L613D	Pathogenic	0.89
NPC1	O15118-1.2	L613E	Pathogenic	0.838
NPC1	O15118-1.2	L613F	Pathogenic	0.77
NPC1	O15118-1.2	L613G	Pathogenic	0.932
NPC1	O15118-1.2	L613H	Pathogenic	0.864
NPC1	O15118-1.2	L613I	Pathogenic	0.591
NPC1	O15118-1.2	L613K	Pathogenic	0.753
NPC1	O15118-1.2	L613M	Pathogenic	0.561
NPC1	O15118-1.2	L613N	Pathogenic	0.85
NPC1	O15118-1.2	L613P	Pathogenic	0.901
NPC1	O15118-1.2	L613Q	Pathogenic	0.797
NPC1	O15118-1.2	L613R	Pathogenic	0.767
NPC1	O15118-1.2	L613S	Pathogenic	0.842
NPC1	O15118-1.2	L613T	Pathogenic	0.78
NPC1	O15118-1.2	L613V	Pathogenic	0.677
NPC1	O15118-1.2	L613W	Pathogenic	0.881
NPC1	O15118-1.2	L613Y	Pathogenic	0.805
NPC1	O15118-1.2	N614A	Pathogenic	0.823
NPC1	O15118-1.2	N614C	Pathogenic	0.83
NPC1	O15118-1.2	N614D	Pathogenic	0.618
NPC1	O15118-1.2	N614E	Pathogenic	0.723
NPC1	O15118-1.2	N614F	Pathogenic	0.816
NPC1	O15118-1.2	N614G	Pathogenic	0.728
NPC1	O15118-1.2	N614H	Pathogenic	0.597
NPC1	O15118-1.2	N614I	Pathogenic	0.805
NPC1	O15118-1.2	N614K	Pathogenic	0.731
NPC1	O15118-1.2	N614L	Pathogenic	0.81
NPC1	O15118-1.2	N614M	Pathogenic	0.773
NPC1	O15118-1.2	N614P	Pathogenic	0.779
NPC1	O15118-1.2	N614Q	Pathogenic	0.705
NPC1	O15118-1.2	N614R	Pathogenic	0.745
NPC1	O15118-1.2	N614S	Pathogenic	0.612
NPC1	O15118-1.2	N614T	Pathogenic	0.651
NPC1	O15118-1.2	N614V	Pathogenic	0.817
NPC1	O15118-1.2	N614W	Pathogenic	0.869
NPC1	O15118-1.2	N614Y	Pathogenic	0.805
NPC1	O15118-1.2	R615A	Pathogenic	0.968
NPC1	O15118-1.2	R615C	Pathogenic	0.979
NPC1	O15118-1.2	R615D	Pathogenic	0.982
NPC1	O15118-1.2	R615E	Pathogenic	0.956
NPC1	O15118-1.2	R615F	Pathogenic	0.963
NPC1	O15118-1.2	R615G	Pathogenic	0.982
NPC1	O15118-1.2	R615H	Pathogenic	0.941
NPC1	O15118-1.2	R615I	Pathogenic	0.966
NPC1	O15118-1.2	R615K	Pathogenic	0.906
NPC1	O15118-1.2	R615L	Pathogenic	0.952
NPC1	O15118-1.2	R615M	Pathogenic	0.94
NPC1	O15118-1.2	R615N	Pathogenic	0.959
NPC1	O15118-1.2	R615P	Pathogenic	0.971
NPC1	O15118-1.2	R615Q	Pathogenic	0.926
NPC1	O15118-1.2	R615S	Pathogenic	0.97
NPC1	O15118-1.2	R615T	Pathogenic	0.963
NPC1	O15118-1.2	R615V	Pathogenic	0.974
NPC1	O15118-1.2	R615W	Pathogenic	0.958
NPC1	O15118-1.2	R615Y	Pathogenic	0.958
NPC1	O15118-1.2	E616A	Pathogenic	0.908
NPC1	O15118-1.2	E616C	Pathogenic	0.957
NPC1	O15118-1.2	E616D	Pathogenic	0.778
NPC1	O15118-1.2	E616F	Pathogenic	0.922
NPC1	O15118-1.2	E616G	Pathogenic	0.947
NPC1	O15118-1.2	E616H	Pathogenic	0.853
NPC1	O15118-1.2	E616I	Pathogenic	0.917
NPC1	O15118-1.2	E616K	Pathogenic	0.834
NPC1	O15118-1.2	E616L	Pathogenic	0.919
NPC1	O15118-1.2	E616M	Pathogenic	0.901
NPC1	O15118-1.2	E616N	Pathogenic	0.884
NPC1	O15118-1.2	E616P	Pathogenic	0.882
NPC1	O15118-1.2	E616Q	Pathogenic	0.747
NPC1	O15118-1.2	E616R	Pathogenic	0.889
NPC1	O15118-1.2	E616S	Pathogenic	0.879
NPC1	O15118-1.2	E616T	Pathogenic	0.895
NPC1	O15118-1.2	E616V	Pathogenic	0.895
NPC1	O15118-1.2	E616W	Pathogenic	0.923
NPC1	O15118-1.2	E616Y	Pathogenic	0.917
NPC1	O15118-1.2	S617A	Pathogenic	0.862
NPC1	O15118-1.2	S617C	Pathogenic	0.918
NPC1	O15118-1.2	S617D	Pathogenic	0.897
NPC1	O15118-1.2	S617E	Pathogenic	0.91
NPC1	O15118-1.2	S617F	Pathogenic	0.945
NPC1	O15118-1.2	S617G	Pathogenic	0.919
NPC1	O15118-1.2	S617H	Pathogenic	0.948
NPC1	O15118-1.2	S617I	Pathogenic	0.941
NPC1	O15118-1.2	S617K	Pathogenic	0.913
NPC1	O15118-1.2	S617L	Pathogenic	0.943
NPC1	O15118-1.2	S617M	Pathogenic	0.929
NPC1	O15118-1.2	S617N	Pathogenic	0.865
NPC1	O15118-1.2	S617P	Pathogenic	0.926
NPC1	O15118-1.2	S617Q	Pathogenic	0.923
NPC1	O15118-1.2	S617R	Pathogenic	0.943
NPC1	O15118-1.2	S617T	Pathogenic	0.874
NPC1	O15118-1.2	S617V	Pathogenic	0.945
NPC1	O15118-1.2	S617W	Pathogenic	0.962
NPC1	O15118-1.2	S617Y	Pathogenic	0.959
NPC1	O15118-1.2	D618A	Neutral	0.219
NPC1	O15118-1.2	D618C	Neutral	0.227
NPC1	O15118-1.2	D618E	Neutral	0.073
NPC1	O15118-1.2	D618F	Neutral	0.222
NPC1	O15118-1.2	D618G	Neutral	0.192
NPC1	O15118-1.2	D618H	Neutral	0.171
NPC1	O15118-1.2	D618I	Neutral	0.209
NPC1	O15118-1.2	D618K	Neutral	0.223
NPC1	O15118-1.2	D618L	Neutral	0.287
NPC1	O15118-1.2	D618M	Neutral	0.243
NPC1	O15118-1.2	D618N	Neutral	0.096
NPC1	O15118-1.2	D618P	Neutral	0.126
NPC1	O15118-1.2	D618Q	Neutral	0.133
NPC1	O15118-1.2	D618R	Neutral	0.312
NPC1	O15118-1.2	D618S	Neutral	0.123
NPC1	O15118-1.2	D618T	Neutral	0.145
NPC1	O15118-1.2	D618V	Neutral	0.223
NPC1	O15118-1.2	D618W	Neutral	0.298
NPC1	O15118-1.2	D618Y	Neutral	0.28
NPC1	O15118-1.2	S619A	Pathogenic	0.632
NPC1	O15118-1.2	S619C	Pathogenic	0.756
NPC1	O15118-1.2	S619D	Pathogenic	0.705
NPC1	O15118-1.2	S619E	Pathogenic	0.736
NPC1	O15118-1.2	S619F	Pathogenic	0.824
NPC1	O15118-1.2	S619G	Pathogenic	0.759
NPC1	O15118-1.2	S619H	Pathogenic	0.833
NPC1	O15118-1.2	S619I	Pathogenic	0.814
NPC1	O15118-1.2	S619K	Pathogenic	0.743
NPC1	O15118-1.2	S619L	Pathogenic	0.819
NPC1	O15118-1.2	S619M	Pathogenic	0.782
NPC1	O15118-1.2	S619N	Pathogenic	0.639
NPC1	O15118-1.2	S619P	Pathogenic	0.776
NPC1	O15118-1.2	S619Q	Pathogenic	0.767
NPC1	O15118-1.2	S619R	Pathogenic	0.821
NPC1	O15118-1.2	S619T	Pathogenic	0.656
NPC1	O15118-1.2	S619V	Pathogenic	0.826
NPC1	O15118-1.2	S619W	Pathogenic	0.875
NPC1	O15118-1.2	S619Y	Pathogenic	0.865
NPC1	O15118-1.2	D620A	Pathogenic	0.97
NPC1	O15118-1.2	D620C	Pathogenic	0.971
NPC1	O15118-1.2	D620E	Pathogenic	0.901
NPC1	O15118-1.2	D620F	Pathogenic	0.971
NPC1	O15118-1.2	D620G	Pathogenic	0.965
NPC1	O15118-1.2	D620H	Pathogenic	0.96
NPC1	O15118-1.2	D620I	Pathogenic	0.968
NPC1	O15118-1.2	D620K	Pathogenic	0.971
NPC1	O15118-1.2	D620L	Pathogenic	0.979
NPC1	O15118-1.2	D620M	Pathogenic	0.974
NPC1	O15118-1.2	D620N	Pathogenic	0.925
NPC1	O15118-1.2	D620P	Pathogenic	0.944
NPC1	O15118-1.2	D620Q	Pathogenic	0.947
NPC1	O15118-1.2	D620R	Pathogenic	0.981
NPC1	O15118-1.2	D620S	Pathogenic	0.942
NPC1	O15118-1.2	D620T	Pathogenic	0.952
NPC1	O15118-1.2	D620V	Pathogenic	0.971
NPC1	O15118-1.2	D620W	Pathogenic	0.98
NPC1	O15118-1.2	D620Y	Pathogenic	0.978
NPC1	O15118-1.2	V621A	Neutral	0.327
NPC1	O15118-1.2	V621C	Neutral	0.443
NPC1	O15118-1.2	V621D	Neutral	0.483
NPC1	O15118-1.2	V621E	Neutral	0.384
NPC1	O15118-1.2	V621F	Neutral	0.432
NPC1	O15118-1.2	V621G	Pathogenic	0.61
NPC1	O15118-1.2	V621H	Pathogenic	0.556
NPC1	O15118-1.2	V621I	Neutral	0.131
NPC1	O15118-1.2	V621K	Neutral	0.394
NPC1	O15118-1.2	V621L	Neutral	0.253
NPC1	O15118-1.2	V621M	Neutral	0.284
NPC1	O15118-1.2	V621N	Neutral	0.489
NPC1	O15118-1.2	V621P	Pathogenic	0.511
NPC1	O15118-1.2	V621Q	Neutral	0.425
NPC1	O15118-1.2	V621R	Pathogenic	0.507
NPC1	O15118-1.2	V621S	Neutral	0.474
NPC1	O15118-1.2	V621T	Neutral	0.289
NPC1	O15118-1.2	V621W	Pathogenic	0.626
NPC1	O15118-1.2	V621Y	Neutral	0.467
NPC1	O15118-1.2	F622A	Neutral	0.075
NPC1	O15118-1.2	F622C	Neutral	0.083
NPC1	O15118-1.2	F622D	Neutral	0.067
NPC1	O15118-1.2	F622E	Neutral	0.063
NPC1	O15118-1.2	F622G	Neutral	0.108
NPC1	O15118-1.2	F622H	Neutral	0.037
NPC1	O15118-1.2	F622I	Neutral	0.041
NPC1	O15118-1.2	F622K	Neutral	0.049
NPC1	O15118-1.2	F622L	Neutral	0.04
NPC1	O15118-1.2	F622M	Neutral	0.035
NPC1	O15118-1.2	F622N	Neutral	0.069
NPC1	O15118-1.2	F622P	Neutral	0.149
NPC1	O15118-1.2	F622Q	Neutral	0.07
NPC1	O15118-1.2	F622R	Neutral	0.052
NPC1	O15118-1.2	F622S	Neutral	0.065
NPC1	O15118-1.2	F622T	Neutral	0.064
NPC1	O15118-1.2	F622V	Neutral	0.056
NPC1	O15118-1.2	F622W	Neutral	0.027
NPC1	O15118-1.2	F622Y	Neutral	0.01
NPC1	O15118-1.2	T623A	Pathogenic	0.717
NPC1	O15118-1.2	T623C	Pathogenic	0.726
NPC1	O15118-1.2	T623D	Pathogenic	0.699
NPC1	O15118-1.2	T623E	Pathogenic	0.726
NPC1	O15118-1.2	T623F	Pathogenic	0.787
NPC1	O15118-1.2	T623G	Pathogenic	0.851
NPC1	O15118-1.2	T623H	Pathogenic	0.841
NPC1	O15118-1.2	T623I	Pathogenic	0.7
NPC1	O15118-1.2	T623K	Pathogenic	0.734
NPC1	O15118-1.2	T623L	Pathogenic	0.707
NPC1	O15118-1.2	T623M	Pathogenic	0.738
NPC1	O15118-1.2	T623N	Pathogenic	0.627
NPC1	O15118-1.2	T623P	Pathogenic	0.738
NPC1	O15118-1.2	T623Q	Pathogenic	0.758
NPC1	O15118-1.2	T623R	Pathogenic	0.748
NPC1	O15118-1.2	T623S	Pathogenic	0.605
NPC1	O15118-1.2	T623V	Pathogenic	0.632
NPC1	O15118-1.2	T623W	Pathogenic	0.789
NPC1	O15118-1.2	T623Y	Pathogenic	0.834
NPC1	O15118-1.2	V624A	Neutral	0.356
NPC1	O15118-1.2	V624C	Neutral	0.476
NPC1	O15118-1.2	V624D	Pathogenic	0.515
NPC1	O15118-1.2	V624E	Neutral	0.416
NPC1	O15118-1.2	V624F	Neutral	0.464
NPC1	O15118-1.2	V624G	Pathogenic	0.64
NPC1	O15118-1.2	V624H	Pathogenic	0.588
NPC1	O15118-1.2	V624I	Neutral	0.147
NPC1	O15118-1.2	V624K	Neutral	0.425
NPC1	O15118-1.2	V624L	Neutral	0.278
NPC1	O15118-1.2	V624M	Neutral	0.311
NPC1	O15118-1.2	V624N	Pathogenic	0.522
NPC1	O15118-1.2	V624P	Pathogenic	0.544
NPC1	O15118-1.2	V624Q	Neutral	0.457
NPC1	O15118-1.2	V624R	Pathogenic	0.54
NPC1	O15118-1.2	V624S	Pathogenic	0.507
NPC1	O15118-1.2	V624T	Neutral	0.317
NPC1	O15118-1.2	V624W	Pathogenic	0.656
NPC1	O15118-1.2	V624Y	Neutral	0.499
NPC1	O15118-1.2	V625A	Neutral	0.168
NPC1	O15118-1.2	V625C	Neutral	0.248
NPC1	O15118-1.2	V625D	Neutral	0.279
NPC1	O15118-1.2	V625E	Neutral	0.206
NPC1	O15118-1.2	V625F	Neutral	0.24
NPC1	O15118-1.2	V625G	Neutral	0.393
NPC1	O15118-1.2	V625H	Neutral	0.342
NPC1	O15118-1.2	V625I	Neutral	0.059
NPC1	O15118-1.2	V625K	Neutral	0.212
NPC1	O15118-1.2	V625L	Neutral	0.123
NPC1	O15118-1.2	V625M	Neutral	0.141
NPC1	O15118-1.2	V625N	Neutral	0.284
NPC1	O15118-1.2	V625P	Neutral	0.303
NPC1	O15118-1.2	V625Q	Neutral	0.235
NPC1	O15118-1.2	V625R	Neutral	0.299
NPC1	O15118-1.2	V625S	Neutral	0.273
NPC1	O15118-1.2	V625T	Neutral	0.145
NPC1	O15118-1.2	V625W	Neutral	0.41
NPC1	O15118-1.2	V625Y	Neutral	0.267
NPC1	O15118-1.2	I626A	Neutral	0.44
NPC1	O15118-1.2	I626C	Neutral	0.468
NPC1	O15118-1.2	I626D	Pathogenic	0.507
NPC1	O15118-1.2	I626E	Neutral	0.491
NPC1	O15118-1.2	I626F	Neutral	0.399
NPC1	O15118-1.2	I626G	Pathogenic	0.717
NPC1	O15118-1.2	I626H	Pathogenic	0.541
NPC1	O15118-1.2	I626K	Neutral	0.456
NPC1	O15118-1.2	I626L	Neutral	0.218
NPC1	O15118-1.2	I626M	Neutral	0.259
NPC1	O15118-1.2	I626N	Pathogenic	0.514
NPC1	O15118-1.2	I626P	Pathogenic	0.629
NPC1	O15118-1.2	I626Q	Pathogenic	0.518
NPC1	O15118-1.2	I626R	Neutral	0.474
NPC1	O15118-1.2	I626S	Neutral	0.499
NPC1	O15118-1.2	I626T	Neutral	0.398
NPC1	O15118-1.2	I626V	Neutral	0.153
NPC1	O15118-1.2	I626W	Pathogenic	0.684
NPC1	O15118-1.2	I626Y	Neutral	0.434
NPC1	O15118-1.2	S627A	Pathogenic	0.706
NPC1	O15118-1.2	S627C	Pathogenic	0.813
NPC1	O15118-1.2	S627D	Pathogenic	0.77
NPC1	O15118-1.2	S627E	Pathogenic	0.796
NPC1	O15118-1.2	S627F	Pathogenic	0.868
NPC1	O15118-1.2	S627G	Pathogenic	0.815
NPC1	O15118-1.2	S627H	Pathogenic	0.875
NPC1	O15118-1.2	S627I	Pathogenic	0.859
NPC1	O15118-1.2	S627K	Pathogenic	0.802
NPC1	O15118-1.2	S627L	Pathogenic	0.863
NPC1	O15118-1.2	S627M	Pathogenic	0.834
NPC1	O15118-1.2	S627N	Pathogenic	0.712
NPC1	O15118-1.2	S627P	Pathogenic	0.829
NPC1	O15118-1.2	S627Q	Pathogenic	0.822
NPC1	O15118-1.2	S627R	Pathogenic	0.865
NPC1	O15118-1.2	S627T	Pathogenic	0.727
NPC1	O15118-1.2	S627V	Pathogenic	0.869
NPC1	O15118-1.2	S627W	Pathogenic	0.907
NPC1	O15118-1.2	S627Y	Pathogenic	0.9
NPC1	O15118-1.2	Y628A	Pathogenic	0.939
NPC1	O15118-1.2	Y628C	Pathogenic	0.944
NPC1	O15118-1.2	Y628D	Pathogenic	0.931
NPC1	O15118-1.2	Y628E	Pathogenic	0.896
NPC1	O15118-1.2	Y628F	Pathogenic	0.581
NPC1	O15118-1.2	Y628G	Pathogenic	0.958
NPC1	O15118-1.2	Y628H	Pathogenic	0.694
NPC1	O15118-1.2	Y628I	Pathogenic	0.874
NPC1	O15118-1.2	Y628K	Pathogenic	0.868
NPC1	O15118-1.2	Y628L	Pathogenic	0.877
NPC1	O15118-1.2	Y628M	Pathogenic	0.893
NPC1	O15118-1.2	Y628N	Pathogenic	0.905
NPC1	O15118-1.2	Y628P	Pathogenic	0.957
NPC1	O15118-1.2	Y628Q	Pathogenic	0.868
NPC1	O15118-1.2	Y628R	Pathogenic	0.868
NPC1	O15118-1.2	Y628S	Pathogenic	0.929
NPC1	O15118-1.2	Y628T	Pathogenic	0.928
NPC1	O15118-1.2	Y628V	Pathogenic	0.904
NPC1	O15118-1.2	Y628W	Pathogenic	0.659
NPC1	O15118-1.2	A629C	Neutral	0.077
NPC1	O15118-1.2	A629D	Neutral	0.139
NPC1	O15118-1.2	A629E	Neutral	0.114
NPC1	O15118-1.2	A629F	Neutral	0.156
NPC1	O15118-1.2	A629G	Neutral	0.086
NPC1	O15118-1.2	A629H	Neutral	0.205
NPC1	O15118-1.2	A629I	Neutral	0.105
NPC1	O15118-1.2	A629K	Neutral	0.118
NPC1	O15118-1.2	A629L	Neutral	0.108
NPC1	O15118-1.2	A629M	Neutral	0.124
NPC1	O15118-1.2	A629N	Neutral	0.15
NPC1	O15118-1.2	A629P	Neutral	0.12
NPC1	O15118-1.2	A629Q	Neutral	0.132
NPC1	O15118-1.2	A629R	Neutral	0.126
NPC1	O15118-1.2	A629S	Neutral	0.055
NPC1	O15118-1.2	A629T	Neutral	0.096
NPC1	O15118-1.2	A629V	Neutral	0.079
NPC1	O15118-1.2	A629W	Neutral	0.216
NPC1	O15118-1.2	A629Y	Neutral	0.202
NPC1	O15118-1.2	I630A	Neutral	0.477
NPC1	O15118-1.2	I630C	Pathogenic	0.504
NPC1	O15118-1.2	I630D	Pathogenic	0.544
NPC1	O15118-1.2	I630E	Pathogenic	0.528
NPC1	O15118-1.2	I630F	Neutral	0.434
NPC1	O15118-1.2	I630G	Pathogenic	0.746
NPC1	O15118-1.2	I630H	Pathogenic	0.577
NPC1	O15118-1.2	I630K	Neutral	0.492
NPC1	O15118-1.2	I630L	Neutral	0.244
NPC1	O15118-1.2	I630M	Neutral	0.289
NPC1	O15118-1.2	I630N	Pathogenic	0.55
NPC1	O15118-1.2	I630P	Pathogenic	0.663
NPC1	O15118-1.2	I630Q	Pathogenic	0.555
NPC1	O15118-1.2	I630R	Pathogenic	0.511
NPC1	O15118-1.2	I630S	Pathogenic	0.536
NPC1	O15118-1.2	I630T	Neutral	0.434
NPC1	O15118-1.2	I630V	Neutral	0.173
NPC1	O15118-1.2	I630W	Pathogenic	0.715
NPC1	O15118-1.2	I630Y	Neutral	0.471
NPC1	O15118-1.2	M631A	Pathogenic	0.852
NPC1	O15118-1.2	M631C	Pathogenic	0.866
NPC1	O15118-1.2	M631D	Pathogenic	0.883
NPC1	O15118-1.2	M631E	Pathogenic	0.828
NPC1	O15118-1.2	M631F	Pathogenic	0.77
NPC1	O15118-1.2	M631G	Pathogenic	0.927
NPC1	O15118-1.2	M631H	Pathogenic	0.855
NPC1	O15118-1.2	M631I	Pathogenic	0.68
NPC1	O15118-1.2	M631K	Pathogenic	0.739
NPC1	O15118-1.2	M631L	Pathogenic	0.599
NPC1	O15118-1.2	M631N	Pathogenic	0.84
NPC1	O15118-1.2	M631P	Pathogenic	0.894
NPC1	O15118-1.2	M631Q	Pathogenic	0.712
NPC1	O15118-1.2	M631R	Pathogenic	0.753
NPC1	O15118-1.2	M631S	Pathogenic	0.832
NPC1	O15118-1.2	M631T	Pathogenic	0.829
NPC1	O15118-1.2	M631V	Pathogenic	0.741
NPC1	O15118-1.2	M631W	Pathogenic	0.834
NPC1	O15118-1.2	M631Y	Pathogenic	0.849
NPC1	O15118-1.2	F632A	Pathogenic	0.894
NPC1	O15118-1.2	F632C	Pathogenic	0.904
NPC1	O15118-1.2	F632D	Pathogenic	0.882
NPC1	O15118-1.2	F632E	Pathogenic	0.875
NPC1	O15118-1.2	F632G	Pathogenic	0.926
NPC1	O15118-1.2	F632H	Pathogenic	0.799
NPC1	O15118-1.2	F632I	Pathogenic	0.818
NPC1	O15118-1.2	F632K	Pathogenic	0.842
NPC1	O15118-1.2	F632L	Pathogenic	0.814
NPC1	O15118-1.2	F632M	Pathogenic	0.79
NPC1	O15118-1.2	F632N	Pathogenic	0.885
NPC1	O15118-1.2	F632P	Pathogenic	0.948
NPC1	O15118-1.2	F632Q	Pathogenic	0.887
NPC1	O15118-1.2	F632R	Pathogenic	0.852
NPC1	O15118-1.2	F632S	Pathogenic	0.879
NPC1	O15118-1.2	F632T	Pathogenic	0.876
NPC1	O15118-1.2	F632V	Pathogenic	0.86
NPC1	O15118-1.2	F632W	Pathogenic	0.745
NPC1	O15118-1.2	F632Y	Pathogenic	0.511
NPC1	O15118-1.2	L633A	Neutral	0.141
NPC1	O15118-1.2	L633C	Neutral	0.155
NPC1	O15118-1.2	L633D	Neutral	0.24
NPC1	O15118-1.2	L633E	Neutral	0.168
NPC1	O15118-1.2	L633F	Neutral	0.116
NPC1	O15118-1.2	L633G	Neutral	0.346
NPC1	O15118-1.2	L633H	Neutral	0.198
NPC1	O15118-1.2	L633I	Neutral	0.053
NPC1	O15118-1.2	L633K	Neutral	0.106
NPC1	O15118-1.2	L633M	Neutral	0.047
NPC1	O15118-1.2	L633N	Neutral	0.181
NPC1	O15118-1.2	L633P	Neutral	0.262
NPC1	O15118-1.2	L633Q	Neutral	0.133
NPC1	O15118-1.2	L633R	Neutral	0.114
NPC1	O15118-1.2	L633S	Neutral	0.172
NPC1	O15118-1.2	L633T	Neutral	0.121
NPC1	O15118-1.2	L633V	Neutral	0.076
NPC1	O15118-1.2	L633W	Neutral	0.223
NPC1	O15118-1.2	L633Y	Neutral	0.138
NPC1	O15118-1.2	Y634A	Pathogenic	0.935
NPC1	O15118-1.2	Y634C	Pathogenic	0.94
NPC1	O15118-1.2	Y634D	Pathogenic	0.927
NPC1	O15118-1.2	Y634E	Pathogenic	0.891
NPC1	O15118-1.2	Y634F	Pathogenic	0.566
NPC1	O15118-1.2	Y634G	Pathogenic	0.955
NPC1	O15118-1.2	Y634H	Pathogenic	0.68
NPC1	O15118-1.2	Y634I	Pathogenic	0.867
NPC1	O15118-1.2	Y634K	Pathogenic	0.861
NPC1	O15118-1.2	Y634L	Pathogenic	0.87
NPC1	O15118-1.2	Y634M	Pathogenic	0.887
NPC1	O15118-1.2	Y634N	Pathogenic	0.899
NPC1	O15118-1.2	Y634P	Pathogenic	0.955
NPC1	O15118-1.2	Y634Q	Pathogenic	0.86
NPC1	O15118-1.2	Y634R	Pathogenic	0.861
NPC1	O15118-1.2	Y634S	Pathogenic	0.925
NPC1	O15118-1.2	Y634T	Pathogenic	0.923
NPC1	O15118-1.2	Y634V	Pathogenic	0.898
NPC1	O15118-1.2	Y634W	Pathogenic	0.644
NPC1	O15118-1.2	I635A	Pathogenic	0.757
NPC1	O15118-1.2	I635C	Pathogenic	0.777
NPC1	O15118-1.2	I635D	Pathogenic	0.803
NPC1	O15118-1.2	I635E	Pathogenic	0.793
NPC1	O15118-1.2	I635F	Pathogenic	0.724
NPC1	O15118-1.2	I635G	Pathogenic	0.91
NPC1	O15118-1.2	I635H	Pathogenic	0.824
NPC1	O15118-1.2	I635K	Pathogenic	0.769
NPC1	O15118-1.2	I635L	Pathogenic	0.525
NPC1	O15118-1.2	I635M	Pathogenic	0.582
NPC1	O15118-1.2	I635N	Pathogenic	0.807
NPC1	O15118-1.2	I635P	Pathogenic	0.871
NPC1	O15118-1.2	I635Q	Pathogenic	0.81
NPC1	O15118-1.2	I635R	Pathogenic	0.781
NPC1	O15118-1.2	I635S	Pathogenic	0.798
NPC1	O15118-1.2	I635T	Pathogenic	0.724
NPC1	O15118-1.2	I635V	Neutral	0.418
NPC1	O15118-1.2	I635W	Pathogenic	0.896
NPC1	O15118-1.2	I635Y	Pathogenic	0.753
NPC1	O15118-1.2	S636A	Neutral	0.284
NPC1	O15118-1.2	S636C	Neutral	0.417
NPC1	O15118-1.2	S636D	Neutral	0.355
NPC1	O15118-1.2	S636E	Neutral	0.391
NPC1	O15118-1.2	S636F	Pathogenic	0.52
NPC1	O15118-1.2	S636G	Neutral	0.42
NPC1	O15118-1.2	S636H	Pathogenic	0.535
NPC1	O15118-1.2	S636I	Pathogenic	0.502
NPC1	O15118-1.2	S636K	Neutral	0.401
NPC1	O15118-1.2	S636L	Pathogenic	0.51
NPC1	O15118-1.2	S636M	Neutral	0.453
NPC1	O15118-1.2	S636N	Neutral	0.29
NPC1	O15118-1.2	S636P	Neutral	0.444
NPC1	O15118-1.2	S636Q	Neutral	0.432
NPC1	O15118-1.2	S636R	Pathogenic	0.514
NPC1	O15118-1.2	S636T	Neutral	0.305
NPC1	O15118-1.2	S636V	Pathogenic	0.522
NPC1	O15118-1.2	S636W	Pathogenic	0.618
NPC1	O15118-1.2	S636Y	Pathogenic	0.596
NPC1	O15118-1.2	L637A	Neutral	0.254
NPC1	O15118-1.2	L637C	Neutral	0.275
NPC1	O15118-1.2	L637D	Neutral	0.396
NPC1	O15118-1.2	L637E	Neutral	0.294
NPC1	O15118-1.2	L637F	Neutral	0.213
NPC1	O15118-1.2	L637G	Pathogenic	0.523
NPC1	O15118-1.2	L637H	Neutral	0.338
NPC1	O15118-1.2	L637I	Neutral	0.104
NPC1	O15118-1.2	L637K	Neutral	0.198
NPC1	O15118-1.2	L637M	Neutral	0.093
NPC1	O15118-1.2	L637N	Neutral	0.314
NPC1	O15118-1.2	L637P	Neutral	0.423
NPC1	O15118-1.2	L637Q	Neutral	0.24
NPC1	O15118-1.2	L637R	Neutral	0.21
NPC1	O15118-1.2	L637S	Neutral	0.301
NPC1	O15118-1.2	L637T	Neutral	0.222
NPC1	O15118-1.2	L637V	Neutral	0.145
NPC1	O15118-1.2	L637W	Neutral	0.373
NPC1	O15118-1.2	L637Y	Neutral	0.249
NPC1	O15118-1.2	A638C	Neutral	0.484
NPC1	O15118-1.2	A638D	Pathogenic	0.646
NPC1	O15118-1.2	A638E	Pathogenic	0.591
NPC1	O15118-1.2	A638F	Pathogenic	0.676
NPC1	O15118-1.2	A638G	Pathogenic	0.514
NPC1	O15118-1.2	A638H	Pathogenic	0.744
NPC1	O15118-1.2	A638I	Pathogenic	0.569
NPC1	O15118-1.2	A638K	Pathogenic	0.601
NPC1	O15118-1.2	A638L	Pathogenic	0.577
NPC1	O15118-1.2	A638M	Pathogenic	0.615
NPC1	O15118-1.2	A638N	Pathogenic	0.666
NPC1	O15118-1.2	A638P	Pathogenic	0.606
NPC1	O15118-1.2	A638Q	Pathogenic	0.631
NPC1	O15118-1.2	A638R	Pathogenic	0.619
NPC1	O15118-1.2	A638S	Neutral	0.396
NPC1	O15118-1.2	A638T	Pathogenic	0.546
NPC1	O15118-1.2	A638V	Neutral	0.493
NPC1	O15118-1.2	A638W	Pathogenic	0.757
NPC1	O15118-1.2	A638Y	Pathogenic	0.74
NPC1	O15118-1.2	L639A	Pathogenic	0.831
NPC1	O15118-1.2	L639C	Pathogenic	0.846
NPC1	O15118-1.2	L639D	Pathogenic	0.904
NPC1	O15118-1.2	L639E	Pathogenic	0.857
NPC1	O15118-1.2	L639F	Pathogenic	0.796
NPC1	O15118-1.2	L639G	Pathogenic	0.941
NPC1	O15118-1.2	L639H	Pathogenic	0.88
NPC1	O15118-1.2	L639I	Pathogenic	0.627
NPC1	O15118-1.2	L639K	Pathogenic	0.78
NPC1	O15118-1.2	L639M	Pathogenic	0.598
NPC1	O15118-1.2	L639N	Pathogenic	0.868
NPC1	O15118-1.2	L639P	Pathogenic	0.914
NPC1	O15118-1.2	L639Q	Pathogenic	0.82
NPC1	O15118-1.2	L639R	Pathogenic	0.793
NPC1	O15118-1.2	L639S	Pathogenic	0.861
NPC1	O15118-1.2	L639T	Pathogenic	0.805
NPC1	O15118-1.2	L639V	Pathogenic	0.709
NPC1	O15118-1.2	L639W	Pathogenic	0.895
NPC1	O15118-1.2	L639Y	Pathogenic	0.827
NPC1	O15118-1.2	G640A	Pathogenic	0.813
NPC1	O15118-1.2	G640C	Pathogenic	0.925
NPC1	O15118-1.2	G640D	Pathogenic	0.864
NPC1	O15118-1.2	G640E	Pathogenic	0.916
NPC1	O15118-1.2	G640F	Pathogenic	0.927
NPC1	O15118-1.2	G640H	Pathogenic	0.931
NPC1	O15118-1.2	G640I	Pathogenic	0.946
NPC1	O15118-1.2	G640K	Pathogenic	0.919
NPC1	O15118-1.2	G640L	Pathogenic	0.948
NPC1	O15118-1.2	G640M	Pathogenic	0.935
NPC1	O15118-1.2	G640N	Pathogenic	0.824
NPC1	O15118-1.2	G640P	Pathogenic	0.904
NPC1	O15118-1.2	G640Q	Pathogenic	0.928
NPC1	O15118-1.2	G640R	Pathogenic	0.924
NPC1	O15118-1.2	G640S	Pathogenic	0.831
NPC1	O15118-1.2	G640T	Pathogenic	0.918
NPC1	O15118-1.2	G640V	Pathogenic	0.928
NPC1	O15118-1.2	G640W	Pathogenic	0.898
NPC1	O15118-1.2	G640Y	Pathogenic	0.946
NPC1	O15118-1.2	H641A	Pathogenic	0.651
NPC1	O15118-1.2	H641C	Pathogenic	0.662
NPC1	O15118-1.2	H641D	Neutral	0.463
NPC1	O15118-1.2	H641E	Neutral	0.355
NPC1	O15118-1.2	H641F	Neutral	0.387
NPC1	O15118-1.2	H641G	Pathogenic	0.68
NPC1	O15118-1.2	H641I	Pathogenic	0.56
NPC1	O15118-1.2	H641K	Neutral	0.43
NPC1	O15118-1.2	H641L	Pathogenic	0.568
NPC1	O15118-1.2	H641M	Pathogenic	0.511
NPC1	O15118-1.2	H641N	Neutral	0.29
NPC1	O15118-1.2	H641P	Pathogenic	0.586
NPC1	O15118-1.2	H641Q	Neutral	0.38
NPC1	O15118-1.2	H641R	Neutral	0.356
NPC1	O15118-1.2	H641S	Pathogenic	0.551
NPC1	O15118-1.2	H641T	Pathogenic	0.619
NPC1	O15118-1.2	H641V	Pathogenic	0.617
NPC1	O15118-1.2	H641W	Neutral	0.486
NPC1	O15118-1.2	H641Y	Neutral	0.213
NPC1	O15118-1.2	M642A	Neutral	0.454
NPC1	O15118-1.2	M642C	Neutral	0.481
NPC1	O15118-1.2	M642D	Pathogenic	0.521
NPC1	O15118-1.2	M642E	Neutral	0.409
NPC1	O15118-1.2	M642F	Neutral	0.326
NPC1	O15118-1.2	M642G	Pathogenic	0.645
NPC1	O15118-1.2	M642H	Neutral	0.458
NPC1	O15118-1.2	M642I	Neutral	0.234
NPC1	O15118-1.2	M642K	Neutral	0.29
NPC1	O15118-1.2	M642L	Neutral	0.177
NPC1	O15118-1.2	M642N	Neutral	0.431
NPC1	O15118-1.2	M642P	Pathogenic	0.549
NPC1	O15118-1.2	M642Q	Neutral	0.263
NPC1	O15118-1.2	M642R	Neutral	0.305
NPC1	O15118-1.2	M642S	Neutral	0.417
NPC1	O15118-1.2	M642T	Neutral	0.411
NPC1	O15118-1.2	M642V	Neutral	0.292
NPC1	O15118-1.2	M642W	Neutral	0.419
NPC1	O15118-1.2	M642Y	Neutral	0.447
NPC1	O15118-1.2	K643A	Neutral	0.351
NPC1	O15118-1.2	K643C	Neutral	0.454
NPC1	O15118-1.2	K643D	Neutral	0.4
NPC1	O15118-1.2	K643E	Neutral	0.209
NPC1	O15118-1.2	K643F	Neutral	0.321
NPC1	O15118-1.2	K643G	Neutral	0.497
NPC1	O15118-1.2	K643H	Neutral	0.296
NPC1	O15118-1.2	K643I	Neutral	0.335
NPC1	O15118-1.2	K643L	Neutral	0.261
NPC1	O15118-1.2	K643M	Neutral	0.22
NPC1	O15118-1.2	K643N	Neutral	0.294
NPC1	O15118-1.2	K643P	Neutral	0.291
NPC1	O15118-1.2	K643Q	Neutral	0.183
NPC1	O15118-1.2	K643R	Neutral	0.157
NPC1	O15118-1.2	K643S	Neutral	0.284
NPC1	O15118-1.2	K643T	Neutral	0.319
NPC1	O15118-1.2	K643V	Neutral	0.318
NPC1	O15118-1.2	K643W	Neutral	0.325
NPC1	O15118-1.2	K643Y	Neutral	0.305
NPC1	O15118-1.2	S644A	Neutral	0.495
NPC1	O15118-1.2	S644C	Pathogenic	0.638
NPC1	O15118-1.2	S644D	Pathogenic	0.576
NPC1	O15118-1.2	S644E	Pathogenic	0.613
NPC1	O15118-1.2	S644F	Pathogenic	0.728
NPC1	O15118-1.2	S644G	Pathogenic	0.641
NPC1	O15118-1.2	S644H	Pathogenic	0.74
NPC1	O15118-1.2	S644I	Pathogenic	0.713
NPC1	O15118-1.2	S644K	Pathogenic	0.623
NPC1	O15118-1.2	S644L	Pathogenic	0.72
NPC1	O15118-1.2	S644M	Pathogenic	0.671
NPC1	O15118-1.2	S644N	Pathogenic	0.502
NPC1	O15118-1.2	S644P	Pathogenic	0.664
NPC1	O15118-1.2	S644Q	Pathogenic	0.652
NPC1	O15118-1.2	S644R	Pathogenic	0.723
NPC1	O15118-1.2	S644T	Pathogenic	0.52
NPC1	O15118-1.2	S644V	Pathogenic	0.729
NPC1	O15118-1.2	S644W	Pathogenic	0.8
NPC1	O15118-1.2	S644Y	Pathogenic	0.785
NPC1	O15118-1.2	C645A	Pathogenic	0.688
NPC1	O15118-1.2	C645D	Pathogenic	0.818
NPC1	O15118-1.2	C645E	Pathogenic	0.885
NPC1	O15118-1.2	C645F	Pathogenic	0.845
NPC1	O15118-1.2	C645G	Pathogenic	0.876
NPC1	O15118-1.2	C645H	Pathogenic	0.877
NPC1	O15118-1.2	C645I	Pathogenic	0.776
NPC1	O15118-1.2	C645K	Pathogenic	0.845
NPC1	O15118-1.2	C645L	Pathogenic	0.782
NPC1	O15118-1.2	C645M	Pathogenic	0.807
NPC1	O15118-1.2	C645N	Pathogenic	0.831
NPC1	O15118-1.2	C645P	Pathogenic	0.88
NPC1	O15118-1.2	C645Q	Pathogenic	0.861
NPC1	O15118-1.2	C645R	Pathogenic	0.854
NPC1	O15118-1.2	C645S	Pathogenic	0.736
NPC1	O15118-1.2	C645T	Pathogenic	0.747
NPC1	O15118-1.2	C645V	Pathogenic	0.789
NPC1	O15118-1.2	C645W	Pathogenic	0.847
NPC1	O15118-1.2	C645Y	Pathogenic	0.88
NPC1	O15118-1.2	R646A	Neutral	0.339
NPC1	O15118-1.2	R646C	Neutral	0.442
NPC1	O15118-1.2	R646D	Neutral	0.483
NPC1	O15118-1.2	R646E	Neutral	0.271
NPC1	O15118-1.2	R646F	Neutral	0.311
NPC1	O15118-1.2	R646G	Neutral	0.484
NPC1	O15118-1.2	R646H	Neutral	0.214
NPC1	O15118-1.2	R646I	Neutral	0.324
NPC1	O15118-1.2	R646K	Neutral	0.141
NPC1	O15118-1.2	R646L	Neutral	0.252
NPC1	O15118-1.2	R646M	Neutral	0.211
NPC1	O15118-1.2	R646N	Neutral	0.284
NPC1	O15118-1.2	R646P	Neutral	0.365
NPC1	O15118-1.2	R646Q	Neutral	0.176
NPC1	O15118-1.2	R646S	Neutral	0.357
NPC1	O15118-1.2	R646T	Neutral	0.309
NPC1	O15118-1.2	R646V	Neutral	0.395
NPC1	O15118-1.2	R646W	Neutral	0.281
NPC1	O15118-1.2	R646Y	Neutral	0.28
NPC1	O15118-1.2	R647A	Pathogenic	0.909
NPC1	O15118-1.2	R647C	Pathogenic	0.939
NPC1	O15118-1.2	R647D	Pathogenic	0.948
NPC1	O15118-1.2	R647E	Pathogenic	0.878
NPC1	O15118-1.2	R647F	Pathogenic	0.897
NPC1	O15118-1.2	R647G	Pathogenic	0.948
NPC1	O15118-1.2	R647H	Pathogenic	0.84
NPC1	O15118-1.2	R647I	Pathogenic	0.903
NPC1	O15118-1.2	R647K	Pathogenic	0.761
NPC1	O15118-1.2	R647L	Pathogenic	0.867
NPC1	O15118-1.2	R647M	Pathogenic	0.838
NPC1	O15118-1.2	R647N	Pathogenic	0.885
NPC1	O15118-1.2	R647P	Pathogenic	0.917
NPC1	O15118-1.2	R647Q	Pathogenic	0.805
NPC1	O15118-1.2	R647S	Pathogenic	0.915
NPC1	O15118-1.2	R647T	Pathogenic	0.896
NPC1	O15118-1.2	R647V	Pathogenic	0.927
NPC1	O15118-1.2	R647W	Pathogenic	0.883
NPC1	O15118-1.2	R647Y	Pathogenic	0.883
NPC1	O15118-1.2	L648A	Pathogenic	0.531
NPC1	O15118-1.2	L648C	Pathogenic	0.558
NPC1	O15118-1.2	L648D	Pathogenic	0.685
NPC1	O15118-1.2	L648E	Pathogenic	0.581
NPC1	O15118-1.2	L648F	Neutral	0.473
NPC1	O15118-1.2	L648G	Pathogenic	0.785
NPC1	O15118-1.2	L648H	Pathogenic	0.629
NPC1	O15118-1.2	L648I	Neutral	0.279
NPC1	O15118-1.2	L648K	Neutral	0.45
NPC1	O15118-1.2	L648M	Neutral	0.255
NPC1	O15118-1.2	L648N	Pathogenic	0.603
NPC1	O15118-1.2	L648P	Pathogenic	0.71
NPC1	O15118-1.2	L648Q	Pathogenic	0.513
NPC1	O15118-1.2	L648R	Neutral	0.469
NPC1	O15118-1.2	L648S	Pathogenic	0.589
NPC1	O15118-1.2	L648T	Neutral	0.487
NPC1	O15118-1.2	L648V	Neutral	0.36
NPC1	O15118-1.2	L648W	Pathogenic	0.664
NPC1	O15118-1.2	L648Y	Pathogenic	0.525
NPC1	O15118-1.2	L649A	Pathogenic	0.844
NPC1	O15118-1.2	L649C	Pathogenic	0.858
NPC1	O15118-1.2	L649D	Pathogenic	0.912
NPC1	O15118-1.2	L649E	Pathogenic	0.869
NPC1	O15118-1.2	L649F	Pathogenic	0.811
NPC1	O15118-1.2	L649G	Pathogenic	0.946
NPC1	O15118-1.2	L649H	Pathogenic	0.89
NPC1	O15118-1.2	L649I	Pathogenic	0.649
NPC1	O15118-1.2	L649K	Pathogenic	0.796
NPC1	O15118-1.2	L649M	Pathogenic	0.621
NPC1	O15118-1.2	L649N	Pathogenic	0.879
NPC1	O15118-1.2	L649P	Pathogenic	0.921
NPC1	O15118-1.2	L649Q	Pathogenic	0.834
NPC1	O15118-1.2	L649R	Pathogenic	0.808
NPC1	O15118-1.2	L649S	Pathogenic	0.872
NPC1	O15118-1.2	L649T	Pathogenic	0.82
NPC1	O15118-1.2	L649V	Pathogenic	0.729
NPC1	O15118-1.2	L649W	Pathogenic	0.904
NPC1	O15118-1.2	L649Y	Pathogenic	0.841
NPC1	O15118-1.2	V650A	Pathogenic	0.705
NPC1	O15118-1.2	V650C	Pathogenic	0.797
NPC1	O15118-1.2	V650D	Pathogenic	0.821
NPC1	O15118-1.2	V650E	Pathogenic	0.754
NPC1	O15118-1.2	V650F	Pathogenic	0.789
NPC1	O15118-1.2	V650G	Pathogenic	0.885
NPC1	O15118-1.2	V650H	Pathogenic	0.86
NPC1	O15118-1.2	V650I	Neutral	0.427
NPC1	O15118-1.2	V650K	Pathogenic	0.762
NPC1	O15118-1.2	V650L	Pathogenic	0.625
NPC1	O15118-1.2	V650M	Pathogenic	0.661
NPC1	O15118-1.2	V650N	Pathogenic	0.825
NPC1	O15118-1.2	V650P	Pathogenic	0.837
NPC1	O15118-1.2	V650Q	Pathogenic	0.784
NPC1	O15118-1.2	V650R	Pathogenic	0.835
NPC1	O15118-1.2	V650S	Pathogenic	0.816
NPC1	O15118-1.2	V650T	Pathogenic	0.667
NPC1	O15118-1.2	V650W	Pathogenic	0.892
NPC1	O15118-1.2	V650Y	Pathogenic	0.812
NPC1	O15118-1.2	D651A	Pathogenic	0.957
NPC1	O15118-1.2	D651C	Pathogenic	0.959
NPC1	O15118-1.2	D651E	Pathogenic	0.863
NPC1	O15118-1.2	D651F	Pathogenic	0.958
NPC1	O15118-1.2	D651G	Pathogenic	0.95
NPC1	O15118-1.2	D651H	Pathogenic	0.942
NPC1	O15118-1.2	D651I	Pathogenic	0.955
NPC1	O15118-1.2	D651K	Pathogenic	0.958
NPC1	O15118-1.2	D651L	Pathogenic	0.97
NPC1	O15118-1.2	D651M	Pathogenic	0.962
NPC1	O15118-1.2	D651N	Pathogenic	0.894
NPC1	O15118-1.2	D651P	Pathogenic	0.92
NPC1	O15118-1.2	D651Q	Pathogenic	0.924
NPC1	O15118-1.2	D651R	Pathogenic	0.973
NPC1	O15118-1.2	D651S	Pathogenic	0.918
NPC1	O15118-1.2	D651T	Pathogenic	0.931
NPC1	O15118-1.2	D651V	Pathogenic	0.958
NPC1	O15118-1.2	D651W	Pathogenic	0.971
NPC1	O15118-1.2	D651Y	Pathogenic	0.969
NPC1	O15118-1.2	S652A	Pathogenic	0.866
NPC1	O15118-1.2	S652C	Pathogenic	0.921
NPC1	O15118-1.2	S652D	Pathogenic	0.9
NPC1	O15118-1.2	S652E	Pathogenic	0.913
NPC1	O15118-1.2	S652F	Pathogenic	0.946
NPC1	O15118-1.2	S652G	Pathogenic	0.922
NPC1	O15118-1.2	S652H	Pathogenic	0.949
NPC1	O15118-1.2	S652I	Pathogenic	0.943
NPC1	O15118-1.2	S652K	Pathogenic	0.916
NPC1	O15118-1.2	S652L	Pathogenic	0.944
NPC1	O15118-1.2	S652M	Pathogenic	0.931
NPC1	O15118-1.2	S652N	Pathogenic	0.869
NPC1	O15118-1.2	S652P	Pathogenic	0.929
NPC1	O15118-1.2	S652Q	Pathogenic	0.925
NPC1	O15118-1.2	S652R	Pathogenic	0.945
NPC1	O15118-1.2	S652T	Pathogenic	0.877
NPC1	O15118-1.2	S652V	Pathogenic	0.947
NPC1	O15118-1.2	S652W	Pathogenic	0.963
NPC1	O15118-1.2	S652Y	Pathogenic	0.96
NPC1	O15118-1.2	K653A	Pathogenic	0.955
NPC1	O15118-1.2	K653C	Pathogenic	0.97
NPC1	O15118-1.2	K653D	Pathogenic	0.963
NPC1	O15118-1.2	K653E	Pathogenic	0.912
NPC1	O15118-1.2	K653F	Pathogenic	0.949
NPC1	O15118-1.2	K653G	Pathogenic	0.975
NPC1	O15118-1.2	K653H	Pathogenic	0.943
NPC1	O15118-1.2	K653I	Pathogenic	0.952
NPC1	O15118-1.2	K653L	Pathogenic	0.933
NPC1	O15118-1.2	K653M	Pathogenic	0.917
NPC1	O15118-1.2	K653N	Pathogenic	0.942
NPC1	O15118-1.2	K653P	Pathogenic	0.941
NPC1	O15118-1.2	K653Q	Pathogenic	0.898
NPC1	O15118-1.2	K653R	Pathogenic	0.88
NPC1	O15118-1.2	K653S	Pathogenic	0.94
NPC1	O15118-1.2	K653T	Pathogenic	0.948
NPC1	O15118-1.2	K653V	Pathogenic	0.948
NPC1	O15118-1.2	K653W	Pathogenic	0.95
NPC1	O15118-1.2	K653Y	Pathogenic	0.945
NPC1	O15118-1.2	V654A	Pathogenic	0.54
NPC1	O15118-1.2	V654C	Pathogenic	0.659
NPC1	O15118-1.2	V654D	Pathogenic	0.693
NPC1	O15118-1.2	V654E	Pathogenic	0.602
NPC1	O15118-1.2	V654F	Pathogenic	0.648
NPC1	O15118-1.2	V654G	Pathogenic	0.791
NPC1	O15118-1.2	V654H	Pathogenic	0.752
NPC1	O15118-1.2	V654I	Neutral	0.268
NPC1	O15118-1.2	V654K	Pathogenic	0.611
NPC1	O15118-1.2	V654L	Neutral	0.451
NPC1	O15118-1.2	V654M	Neutral	0.49
NPC1	O15118-1.2	V654N	Pathogenic	0.699
NPC1	O15118-1.2	V654P	Pathogenic	0.717
NPC1	O15118-1.2	V654Q	Pathogenic	0.642
NPC1	O15118-1.2	V654R	Pathogenic	0.714
NPC1	O15118-1.2	V654S	Pathogenic	0.686
NPC1	O15118-1.2	V654T	Neutral	0.497
NPC1	O15118-1.2	V654W	Pathogenic	0.802
NPC1	O15118-1.2	V654Y	Pathogenic	0.68
NPC1	O15118-1.2	S655A	Neutral	0.191
NPC1	O15118-1.2	S655C	Neutral	0.298
NPC1	O15118-1.2	S655D	Neutral	0.247
NPC1	O15118-1.2	S655E	Neutral	0.276
NPC1	O15118-1.2	S655F	Neutral	0.391
NPC1	O15118-1.2	S655G	Neutral	0.301
NPC1	O15118-1.2	S655H	Neutral	0.406
NPC1	O15118-1.2	S655I	Neutral	0.374
NPC1	O15118-1.2	S655K	Neutral	0.284
NPC1	O15118-1.2	S655L	Neutral	0.382
NPC1	O15118-1.2	S655M	Neutral	0.33
NPC1	O15118-1.2	S655N	Neutral	0.195
NPC1	O15118-1.2	S655P	Neutral	0.322
NPC1	O15118-1.2	S655Q	Neutral	0.311
NPC1	O15118-1.2	S655R	Neutral	0.386
NPC1	O15118-1.2	S655T	Neutral	0.207
NPC1	O15118-1.2	S655V	Neutral	0.393
NPC1	O15118-1.2	S655W	Neutral	0.49
NPC1	O15118-1.2	S655Y	Neutral	0.468
NPC1	O15118-1.2	L656A	Pathogenic	0.734
NPC1	O15118-1.2	L656C	Pathogenic	0.755
NPC1	O15118-1.2	L656D	Pathogenic	0.841
NPC1	O15118-1.2	L656E	Pathogenic	0.772
NPC1	O15118-1.2	L656F	Pathogenic	0.686
NPC1	O15118-1.2	L656G	Pathogenic	0.899
NPC1	O15118-1.2	L656H	Pathogenic	0.805
NPC1	O15118-1.2	L656I	Neutral	0.485
NPC1	O15118-1.2	L656K	Pathogenic	0.666
NPC1	O15118-1.2	L656M	Neutral	0.455
NPC1	O15118-1.2	L656N	Pathogenic	0.787
NPC1	O15118-1.2	L656P	Pathogenic	0.856
NPC1	O15118-1.2	L656Q	Pathogenic	0.719
NPC1	O15118-1.2	L656R	Pathogenic	0.682
NPC1	O15118-1.2	L656S	Pathogenic	0.777
NPC1	O15118-1.2	L656T	Pathogenic	0.698
NPC1	O15118-1.2	L656V	Pathogenic	0.578
NPC1	O15118-1.2	L656W	Pathogenic	0.828
NPC1	O15118-1.2	L656Y	Pathogenic	0.729
NPC1	O15118-1.2	G657A	Pathogenic	0.821
NPC1	O15118-1.2	G657C	Pathogenic	0.929
NPC1	O15118-1.2	G657D	Pathogenic	0.87
NPC1	O15118-1.2	G657E	Pathogenic	0.92
NPC1	O15118-1.2	G657F	Pathogenic	0.931
NPC1	O15118-1.2	G657H	Pathogenic	0.935
NPC1	O15118-1.2	G657I	Pathogenic	0.948
NPC1	O15118-1.2	G657K	Pathogenic	0.922
NPC1	O15118-1.2	G657L	Pathogenic	0.95
NPC1	O15118-1.2	G657M	Pathogenic	0.938
NPC1	O15118-1.2	G657N	Pathogenic	0.832
NPC1	O15118-1.2	G657P	Pathogenic	0.908
NPC1	O15118-1.2	G657Q	Pathogenic	0.931
NPC1	O15118-1.2	G657R	Pathogenic	0.928
NPC1	O15118-1.2	G657S	Pathogenic	0.838
NPC1	O15118-1.2	G657T	Pathogenic	0.922
NPC1	O15118-1.2	G657V	Pathogenic	0.931
NPC1	O15118-1.2	G657W	Pathogenic	0.903
NPC1	O15118-1.2	G657Y	Pathogenic	0.948
NPC1	O15118-1.2	I658A	Neutral	0.39
NPC1	O15118-1.2	I658C	Neutral	0.417
NPC1	O15118-1.2	I658D	Neutral	0.456
NPC1	O15118-1.2	I658E	Neutral	0.44
NPC1	O15118-1.2	I658F	Neutral	0.35
NPC1	O15118-1.2	I658G	Pathogenic	0.674
NPC1	O15118-1.2	I658H	Neutral	0.49
NPC1	O15118-1.2	I658K	Neutral	0.405
NPC1	O15118-1.2	I658L	Neutral	0.185
NPC1	O15118-1.2	I658M	Neutral	0.222
NPC1	O15118-1.2	I658N	Neutral	0.462
NPC1	O15118-1.2	I658P	Pathogenic	0.58
NPC1	O15118-1.2	I658Q	Neutral	0.467
NPC1	O15118-1.2	I658R	Neutral	0.423
NPC1	O15118-1.2	I658S	Neutral	0.447
NPC1	O15118-1.2	I658T	Neutral	0.35
NPC1	O15118-1.2	I658V	Neutral	0.128
NPC1	O15118-1.2	I658W	Pathogenic	0.638
NPC1	O15118-1.2	I658Y	Neutral	0.384
NPC1	O15118-1.2	A659C	Neutral	0.256
NPC1	O15118-1.2	A659D	Neutral	0.402
NPC1	O15118-1.2	A659E	Neutral	0.347
NPC1	O15118-1.2	A659F	Neutral	0.434
NPC1	O15118-1.2	A659G	Neutral	0.28
NPC1	O15118-1.2	A659H	Pathogenic	0.516
NPC1	O15118-1.2	A659I	Neutral	0.327
NPC1	O15118-1.2	A659K	Neutral	0.357
NPC1	O15118-1.2	A659L	Neutral	0.334
NPC1	O15118-1.2	A659M	Neutral	0.37
NPC1	O15118-1.2	A659N	Neutral	0.423
NPC1	O15118-1.2	A659P	Neutral	0.362
NPC1	O15118-1.2	A659Q	Neutral	0.387
NPC1	O15118-1.2	A659R	Neutral	0.374
NPC1	O15118-1.2	A659S	Neutral	0.195
NPC1	O15118-1.2	A659T	Neutral	0.307
NPC1	O15118-1.2	A659V	Neutral	0.263
NPC1	O15118-1.2	A659W	Pathogenic	0.534
NPC1	O15118-1.2	A659Y	Pathogenic	0.512
NPC1	O15118-1.2	G660A	Pathogenic	0.828
NPC1	O15118-1.2	G660C	Pathogenic	0.932
NPC1	O15118-1.2	G660D	Pathogenic	0.875
NPC1	O15118-1.2	G660E	Pathogenic	0.923
NPC1	O15118-1.2	G660F	Pathogenic	0.934
NPC1	O15118-1.2	G660H	Pathogenic	0.937
NPC1	O15118-1.2	G660I	Pathogenic	0.951
NPC1	O15118-1.2	G660K	Pathogenic	0.926
NPC1	O15118-1.2	G660L	Pathogenic	0.952
NPC1	O15118-1.2	G660M	Pathogenic	0.941
NPC1	O15118-1.2	G660N	Pathogenic	0.838
NPC1	O15118-1.2	G660P	Pathogenic	0.912
NPC1	O15118-1.2	G660Q	Pathogenic	0.934
NPC1	O15118-1.2	G660R	Pathogenic	0.931
NPC1	O15118-1.2	G660S	Pathogenic	0.845
NPC1	O15118-1.2	G660T	Pathogenic	0.925
NPC1	O15118-1.2	G660V	Pathogenic	0.934
NPC1	O15118-1.2	G660W	Pathogenic	0.907
NPC1	O15118-1.2	G660Y	Pathogenic	0.951
NPC1	O15118-1.2	I661A	Pathogenic	0.578
NPC1	O15118-1.2	I661C	Pathogenic	0.605
NPC1	O15118-1.2	I661D	Pathogenic	0.642
NPC1	O15118-1.2	I661E	Pathogenic	0.627
NPC1	O15118-1.2	I661F	Pathogenic	0.536
NPC1	O15118-1.2	I661G	Pathogenic	0.816
NPC1	O15118-1.2	I661H	Pathogenic	0.673
NPC1	O15118-1.2	I661K	Pathogenic	0.594
NPC1	O15118-1.2	I661L	Neutral	0.327
NPC1	O15118-1.2	I661M	Neutral	0.379
NPC1	O15118-1.2	I661N	Pathogenic	0.648
NPC1	O15118-1.2	I661P	Pathogenic	0.748
NPC1	O15118-1.2	I661Q	Pathogenic	0.652
NPC1	O15118-1.2	I661R	Pathogenic	0.611
NPC1	O15118-1.2	I661S	Pathogenic	0.635
NPC1	O15118-1.2	I661T	Pathogenic	0.535
NPC1	O15118-1.2	I661V	Neutral	0.24
NPC1	O15118-1.2	I661W	Pathogenic	0.79
NPC1	O15118-1.2	I661Y	Pathogenic	0.572
NPC1	O15118-1.2	L662A	Neutral	0.433
NPC1	O15118-1.2	L662C	Neutral	0.46
NPC1	O15118-1.2	L662D	Pathogenic	0.595
NPC1	O15118-1.2	L662E	Neutral	0.483
NPC1	O15118-1.2	L662F	Neutral	0.377
NPC1	O15118-1.2	L662G	Pathogenic	0.711
NPC1	O15118-1.2	L662H	Pathogenic	0.533
NPC1	O15118-1.2	L662I	Neutral	0.207
NPC1	O15118-1.2	L662K	Neutral	0.356
NPC1	O15118-1.2	L662M	Neutral	0.188
NPC1	O15118-1.2	L662N	Pathogenic	0.506
NPC1	O15118-1.2	L662P	Pathogenic	0.622
NPC1	O15118-1.2	L662Q	Neutral	0.415
NPC1	O15118-1.2	L662R	Neutral	0.373
NPC1	O15118-1.2	L662S	Neutral	0.491
NPC1	O15118-1.2	L662T	Neutral	0.391
NPC1	O15118-1.2	L662V	Neutral	0.275
NPC1	O15118-1.2	L662W	Pathogenic	0.571
NPC1	O15118-1.2	L662Y	Neutral	0.427
NPC1	O15118-1.2	I663A	Pathogenic	0.634
NPC1	O15118-1.2	I663C	Pathogenic	0.658
NPC1	O15118-1.2	I663D	Pathogenic	0.693
NPC1	O15118-1.2	I663E	Pathogenic	0.679
NPC1	O15118-1.2	I663F	Pathogenic	0.593
NPC1	O15118-1.2	I663G	Pathogenic	0.848
NPC1	O15118-1.2	I663H	Pathogenic	0.722
NPC1	O15118-1.2	I663K	Pathogenic	0.648
NPC1	O15118-1.2	I663L	Neutral	0.379
NPC1	O15118-1.2	I663M	Neutral	0.435
NPC1	O15118-1.2	I663N	Pathogenic	0.699
NPC1	O15118-1.2	I663P	Pathogenic	0.789
NPC1	O15118-1.2	I663Q	Pathogenic	0.702
NPC1	O15118-1.2	I663R	Pathogenic	0.664
NPC1	O15118-1.2	I663S	Pathogenic	0.686
NPC1	O15118-1.2	I663T	Pathogenic	0.592
NPC1	O15118-1.2	I663V	Neutral	0.284
NPC1	O15118-1.2	I663W	Pathogenic	0.826
NPC1	O15118-1.2	I663Y	Pathogenic	0.628
NPC1	O15118-1.2	V664A	Pathogenic	0.772
NPC1	O15118-1.2	V664C	Pathogenic	0.848
NPC1	O15118-1.2	V664D	Pathogenic	0.867
NPC1	O15118-1.2	V664E	Pathogenic	0.813
NPC1	O15118-1.2	V664F	Pathogenic	0.842
NPC1	O15118-1.2	V664G	Pathogenic	0.916
NPC1	O15118-1.2	V664H	Pathogenic	0.897
NPC1	O15118-1.2	V664I	Pathogenic	0.514
NPC1	O15118-1.2	V664K	Pathogenic	0.819
NPC1	O15118-1.2	V664L	Pathogenic	0.703
NPC1	O15118-1.2	V664M	Pathogenic	0.734
NPC1	O15118-1.2	V664N	Pathogenic	0.87
NPC1	O15118-1.2	V664P	Pathogenic	0.88
NPC1	O15118-1.2	V664Q	Pathogenic	0.838
NPC1	O15118-1.2	V664R	Pathogenic	0.878
NPC1	O15118-1.2	V664S	Pathogenic	0.863
NPC1	O15118-1.2	V664T	Pathogenic	0.74
NPC1	O15118-1.2	V664W	Pathogenic	0.921
NPC1	O15118-1.2	V664Y	Pathogenic	0.859
NPC1	O15118-1.2	L665A	Pathogenic	0.702
NPC1	O15118-1.2	L665C	Pathogenic	0.724
NPC1	O15118-1.2	L665D	Pathogenic	0.819
NPC1	O15118-1.2	L665E	Pathogenic	0.743
NPC1	O15118-1.2	L665F	Pathogenic	0.652
NPC1	O15118-1.2	L665G	Pathogenic	0.884
NPC1	O15118-1.2	L665H	Pathogenic	0.779
NPC1	O15118-1.2	L665I	Neutral	0.446
NPC1	O15118-1.2	L665K	Pathogenic	0.63
NPC1	O15118-1.2	L665M	Neutral	0.416
NPC1	O15118-1.2	L665N	Pathogenic	0.76
NPC1	O15118-1.2	L665P	Pathogenic	0.836
NPC1	O15118-1.2	L665Q	Pathogenic	0.686
NPC1	O15118-1.2	L665R	Pathogenic	0.647
NPC1	O15118-1.2	L665S	Pathogenic	0.749
NPC1	O15118-1.2	L665T	Pathogenic	0.664
NPC1	O15118-1.2	L665V	Pathogenic	0.539
NPC1	O15118-1.2	L665W	Pathogenic	0.805
NPC1	O15118-1.2	L665Y	Pathogenic	0.697
NPC1	O15118-1.2	S666A	Neutral	0.125
NPC1	O15118-1.2	S666C	Neutral	0.206
NPC1	O15118-1.2	S666D	Neutral	0.166
NPC1	O15118-1.2	S666E	Neutral	0.189
NPC1	O15118-1.2	S666F	Neutral	0.281
NPC1	O15118-1.2	S666G	Neutral	0.208
NPC1	O15118-1.2	S666H	Neutral	0.294
NPC1	O15118-1.2	S666I	Neutral	0.267
NPC1	O15118-1.2	S666K	Neutral	0.195
NPC1	O15118-1.2	S666L	Neutral	0.274
NPC1	O15118-1.2	S666M	Neutral	0.231
NPC1	O15118-1.2	S666N	Neutral	0.129
NPC1	O15118-1.2	S666P	Neutral	0.224
NPC1	O15118-1.2	S666Q	Neutral	0.216
NPC1	O15118-1.2	S666R	Neutral	0.277
NPC1	O15118-1.2	S666T	Neutral	0.137
NPC1	O15118-1.2	S666V	Neutral	0.283
NPC1	O15118-1.2	S666W	Neutral	0.369
NPC1	O15118-1.2	S666Y	Neutral	0.348
NPC1	O15118-1.2	S667A	Pathogenic	0.673
NPC1	O15118-1.2	S667C	Pathogenic	0.788
NPC1	O15118-1.2	S667D	Pathogenic	0.741
NPC1	O15118-1.2	S667E	Pathogenic	0.769
NPC1	O15118-1.2	S667F	Pathogenic	0.849
NPC1	O15118-1.2	S667G	Pathogenic	0.79
NPC1	O15118-1.2	S667H	Pathogenic	0.857
NPC1	O15118-1.2	S667I	Pathogenic	0.839
NPC1	O15118-1.2	S667K	Pathogenic	0.776
NPC1	O15118-1.2	S667L	Pathogenic	0.844
NPC1	O15118-1.2	S667M	Pathogenic	0.811
NPC1	O15118-1.2	S667N	Pathogenic	0.679
NPC1	O15118-1.2	S667P	Pathogenic	0.806
NPC1	O15118-1.2	S667Q	Pathogenic	0.798
NPC1	O15118-1.2	S667R	Pathogenic	0.846
NPC1	O15118-1.2	S667T	Pathogenic	0.695
NPC1	O15118-1.2	S667V	Pathogenic	0.85
NPC1	O15118-1.2	S667W	Pathogenic	0.893
NPC1	O15118-1.2	S667Y	Pathogenic	0.885
NPC1	O15118-1.2	V668A	Pathogenic	0.777
NPC1	O15118-1.2	V668C	Pathogenic	0.851
NPC1	O15118-1.2	V668D	Pathogenic	0.87
NPC1	O15118-1.2	V668E	Pathogenic	0.818
NPC1	O15118-1.2	V668F	Pathogenic	0.845
NPC1	O15118-1.2	V668G	Pathogenic	0.918
NPC1	O15118-1.2	V668H	Pathogenic	0.9
NPC1	O15118-1.2	V668I	Pathogenic	0.521
NPC1	O15118-1.2	V668K	Pathogenic	0.824
NPC1	O15118-1.2	V668L	Pathogenic	0.709
NPC1	O15118-1.2	V668M	Pathogenic	0.74
NPC1	O15118-1.2	V668N	Pathogenic	0.873
NPC1	O15118-1.2	V668P	Pathogenic	0.883
NPC1	O15118-1.2	V668Q	Pathogenic	0.841
NPC1	O15118-1.2	V668R	Pathogenic	0.881
NPC1	O15118-1.2	V668S	Pathogenic	0.866
NPC1	O15118-1.2	V668T	Pathogenic	0.745
NPC1	O15118-1.2	V668W	Pathogenic	0.923
NPC1	O15118-1.2	V668Y	Pathogenic	0.863
NPC1	O15118-1.2	A669C	Neutral	0.143
NPC1	O15118-1.2	A669D	Neutral	0.246
NPC1	O15118-1.2	A669E	Neutral	0.205
NPC1	O15118-1.2	A669F	Neutral	0.271
NPC1	O15118-1.2	A669G	Neutral	0.159
NPC1	O15118-1.2	A669H	Neutral	0.341
NPC1	O15118-1.2	A669I	Neutral	0.191
NPC1	O15118-1.2	A669K	Neutral	0.212
NPC1	O15118-1.2	A669L	Neutral	0.196
NPC1	O15118-1.2	A669M	Neutral	0.222
NPC1	O15118-1.2	A669N	Neutral	0.262
NPC1	O15118-1.2	A669P	Neutral	0.216
NPC1	O15118-1.2	A669Q	Neutral	0.234
NPC1	O15118-1.2	A669R	Neutral	0.225
NPC1	O15118-1.2	A669S	Neutral	0.105
NPC1	O15118-1.2	A669T	Neutral	0.177
NPC1	O15118-1.2	A669V	Neutral	0.148
NPC1	O15118-1.2	A669W	Neutral	0.357
NPC1	O15118-1.2	A669Y	Neutral	0.337
NPC1	O15118-1.2	C670A	Neutral	0.369
NPC1	O15118-1.2	C670D	Pathogenic	0.544
NPC1	O15118-1.2	C670E	Pathogenic	0.672
NPC1	O15118-1.2	C670F	Pathogenic	0.592
NPC1	O15118-1.2	C670G	Pathogenic	0.653
NPC1	O15118-1.2	C670H	Pathogenic	0.655
NPC1	O15118-1.2	C670I	Neutral	0.479
NPC1	O15118-1.2	C670K	Pathogenic	0.591
NPC1	O15118-1.2	C670L	Neutral	0.487
NPC1	O15118-1.2	C670M	Pathogenic	0.526
NPC1	O15118-1.2	C670N	Pathogenic	0.565
NPC1	O15118-1.2	C670P	Pathogenic	0.66
NPC1	O15118-1.2	C670Q	Pathogenic	0.622
NPC1	O15118-1.2	C670R	Pathogenic	0.609
NPC1	O15118-1.2	C670S	Neutral	0.425
NPC1	O15118-1.2	C670T	Neutral	0.44
NPC1	O15118-1.2	C670V	Neutral	0.499
NPC1	O15118-1.2	C670W	Pathogenic	0.596
NPC1	O15118-1.2	C670Y	Pathogenic	0.661
NPC1	O15118-1.2	S671A	Pathogenic	0.672
NPC1	O15118-1.2	S671C	Pathogenic	0.787
NPC1	O15118-1.2	S671D	Pathogenic	0.74
NPC1	O15118-1.2	S671E	Pathogenic	0.768
NPC1	O15118-1.2	S671F	Pathogenic	0.848
NPC1	O15118-1.2	S671G	Pathogenic	0.789
NPC1	O15118-1.2	S671H	Pathogenic	0.856
NPC1	O15118-1.2	S671I	Pathogenic	0.839
NPC1	O15118-1.2	S671K	Pathogenic	0.776
NPC1	O15118-1.2	S671L	Pathogenic	0.844
NPC1	O15118-1.2	S671M	Pathogenic	0.811
NPC1	O15118-1.2	S671N	Pathogenic	0.679
NPC1	O15118-1.2	S671P	Pathogenic	0.805
NPC1	O15118-1.2	S671Q	Pathogenic	0.797
NPC1	O15118-1.2	S671R	Pathogenic	0.846
NPC1	O15118-1.2	S671T	Pathogenic	0.694
NPC1	O15118-1.2	S671V	Pathogenic	0.849
NPC1	O15118-1.2	S671W	Pathogenic	0.893
NPC1	O15118-1.2	S671Y	Pathogenic	0.884
NPC1	O15118-1.2	L672A	Neutral	0.278
NPC1	O15118-1.2	L672C	Neutral	0.301
NPC1	O15118-1.2	L672D	Neutral	0.426
NPC1	O15118-1.2	L672E	Neutral	0.321
NPC1	O15118-1.2	L672F	Neutral	0.234
NPC1	O15118-1.2	L672G	Pathogenic	0.554
NPC1	O15118-1.2	L672H	Neutral	0.366
NPC1	O15118-1.2	L672I	Neutral	0.116
NPC1	O15118-1.2	L672K	Neutral	0.218
NPC1	O15118-1.2	L672M	Neutral	0.104
NPC1	O15118-1.2	L672N	Neutral	0.341
NPC1	O15118-1.2	L672P	Neutral	0.454
NPC1	O15118-1.2	L672Q	Neutral	0.264
NPC1	O15118-1.2	L672R	Neutral	0.231
NPC1	O15118-1.2	L672S	Neutral	0.328
NPC1	O15118-1.2	L672T	Neutral	0.245
NPC1	O15118-1.2	L672V	Neutral	0.161
NPC1	O15118-1.2	L672W	Neutral	0.402
NPC1	O15118-1.2	L672Y	Neutral	0.273
NPC1	O15118-1.2	G673A	Pathogenic	0.828
NPC1	O15118-1.2	G673C	Pathogenic	0.932
NPC1	O15118-1.2	G673D	Pathogenic	0.875
NPC1	O15118-1.2	G673E	Pathogenic	0.923
NPC1	O15118-1.2	G673F	Pathogenic	0.934
NPC1	O15118-1.2	G673H	Pathogenic	0.937
NPC1	O15118-1.2	G673I	Pathogenic	0.951
NPC1	O15118-1.2	G673K	Pathogenic	0.926
NPC1	O15118-1.2	G673L	Pathogenic	0.952
NPC1	O15118-1.2	G673M	Pathogenic	0.941
NPC1	O15118-1.2	G673N	Pathogenic	0.838
NPC1	O15118-1.2	G673P	Pathogenic	0.912
NPC1	O15118-1.2	G673Q	Pathogenic	0.934
NPC1	O15118-1.2	G673R	Pathogenic	0.931
NPC1	O15118-1.2	G673S	Pathogenic	0.845
NPC1	O15118-1.2	G673T	Pathogenic	0.925
NPC1	O15118-1.2	G673V	Pathogenic	0.934
NPC1	O15118-1.2	G673W	Pathogenic	0.907
NPC1	O15118-1.2	G673Y	Pathogenic	0.951
NPC1	O15118-1.2	V674A	Neutral	0.127
NPC1	O15118-1.2	V674C	Neutral	0.192
NPC1	O15118-1.2	V674D	Neutral	0.218
NPC1	O15118-1.2	V674E	Neutral	0.157
NPC1	O15118-1.2	V674F	Neutral	0.185
NPC1	O15118-1.2	V674G	Neutral	0.319
NPC1	O15118-1.2	V674H	Neutral	0.272
NPC1	O15118-1.2	V674I	Neutral	0.043
NPC1	O15118-1.2	V674K	Neutral	0.163
NPC1	O15118-1.2	V674L	Neutral	0.092
NPC1	O15118-1.2	V674M	Neutral	0.106
NPC1	O15118-1.2	V674N	Neutral	0.223
NPC1	O15118-1.2	V674P	Neutral	0.238
NPC1	O15118-1.2	V674Q	Neutral	0.181
NPC1	O15118-1.2	V674R	Neutral	0.235
NPC1	O15118-1.2	V674S	Neutral	0.213
NPC1	O15118-1.2	V674T	Neutral	0.109
NPC1	O15118-1.2	V674W	Neutral	0.333
NPC1	O15118-1.2	V674Y	Neutral	0.208
NPC1	O15118-1.2	F675A	Pathogenic	0.744
NPC1	O15118-1.2	F675C	Pathogenic	0.765
NPC1	O15118-1.2	F675D	Pathogenic	0.721
NPC1	O15118-1.2	F675E	Pathogenic	0.708
NPC1	O15118-1.2	F675G	Pathogenic	0.813
NPC1	O15118-1.2	F675H	Pathogenic	0.578
NPC1	O15118-1.2	F675I	Pathogenic	0.608
NPC1	O15118-1.2	F675K	Pathogenic	0.648
NPC1	O15118-1.2	F675L	Pathogenic	0.602
NPC1	O15118-1.2	F675M	Pathogenic	0.564
NPC1	O15118-1.2	F675N	Pathogenic	0.727
NPC1	O15118-1.2	F675P	Pathogenic	0.863
NPC1	O15118-1.2	F675Q	Pathogenic	0.73
NPC1	O15118-1.2	F675R	Pathogenic	0.665
NPC1	O15118-1.2	F675S	Pathogenic	0.715
NPC1	O15118-1.2	F675T	Pathogenic	0.71
NPC1	O15118-1.2	F675V	Pathogenic	0.68
NPC1	O15118-1.2	F675W	Pathogenic	0.502
NPC1	O15118-1.2	F675Y	Neutral	0.265
NPC1	O15118-1.2	S676A	Pathogenic	0.665
NPC1	O15118-1.2	S676C	Pathogenic	0.781
NPC1	O15118-1.2	S676D	Pathogenic	0.734
NPC1	O15118-1.2	S676E	Pathogenic	0.762
NPC1	O15118-1.2	S676F	Pathogenic	0.844
NPC1	O15118-1.2	S676G	Pathogenic	0.784
NPC1	O15118-1.2	S676H	Pathogenic	0.852
NPC1	O15118-1.2	S676I	Pathogenic	0.834
NPC1	O15118-1.2	S676K	Pathogenic	0.77
NPC1	O15118-1.2	S676L	Pathogenic	0.839
NPC1	O15118-1.2	S676M	Pathogenic	0.805
NPC1	O15118-1.2	S676N	Pathogenic	0.671
NPC1	O15118-1.2	S676P	Pathogenic	0.8
NPC1	O15118-1.2	S676Q	Pathogenic	0.792
NPC1	O15118-1.2	S676R	Pathogenic	0.841
NPC1	O15118-1.2	S676T	Pathogenic	0.687
NPC1	O15118-1.2	S676V	Pathogenic	0.845
NPC1	O15118-1.2	S676W	Pathogenic	0.89
NPC1	O15118-1.2	S676Y	Pathogenic	0.881
NPC1	O15118-1.2	Y677A	Pathogenic	0.932
NPC1	O15118-1.2	Y677C	Pathogenic	0.938
NPC1	O15118-1.2	Y677D	Pathogenic	0.924
NPC1	O15118-1.2	Y677E	Pathogenic	0.886
NPC1	O15118-1.2	Y677F	Pathogenic	0.555
NPC1	O15118-1.2	Y677G	Pathogenic	0.953
NPC1	O15118-1.2	Y677H	Pathogenic	0.671
NPC1	O15118-1.2	Y677I	Pathogenic	0.861
NPC1	O15118-1.2	Y677K	Pathogenic	0.856
NPC1	O15118-1.2	Y677L	Pathogenic	0.866
NPC1	O15118-1.2	Y677M	Pathogenic	0.883
NPC1	O15118-1.2	Y677N	Pathogenic	0.895
NPC1	O15118-1.2	Y677P	Pathogenic	0.953
NPC1	O15118-1.2	Y677Q	Pathogenic	0.855
NPC1	O15118-1.2	Y677R	Pathogenic	0.856
NPC1	O15118-1.2	Y677S	Pathogenic	0.922
NPC1	O15118-1.2	Y677T	Pathogenic	0.92
NPC1	O15118-1.2	Y677V	Pathogenic	0.895
NPC1	O15118-1.2	Y677W	Pathogenic	0.635
NPC1	O15118-1.2	I678A	Neutral	0.173
NPC1	O15118-1.2	I678C	Neutral	0.189
NPC1	O15118-1.2	I678D	Neutral	0.214
NPC1	O15118-1.2	I678E	Neutral	0.204
NPC1	O15118-1.2	I678F	Neutral	0.149
NPC1	O15118-1.2	I678G	Neutral	0.402
NPC1	O15118-1.2	I678H	Neutral	0.238
NPC1	O15118-1.2	I678K	Neutral	0.182
NPC1	O15118-1.2	I678L	Neutral	0.069
NPC1	O15118-1.2	I678M	Neutral	0.085
NPC1	O15118-1.2	I678N	Neutral	0.219
NPC1	O15118-1.2	I678P	Neutral	0.31
NPC1	O15118-1.2	I678Q	Neutral	0.222
NPC1	O15118-1.2	I678R	Neutral	0.193
NPC1	O15118-1.2	I678S	Neutral	0.209
NPC1	O15118-1.2	I678T	Neutral	0.149
NPC1	O15118-1.2	I678V	Neutral	0.046
NPC1	O15118-1.2	I678W	Neutral	0.365
NPC1	O15118-1.2	I678Y	Neutral	0.169
NPC1	O15118-1.2	G679A	Pathogenic	0.757
NPC1	O15118-1.2	G679C	Pathogenic	0.899
NPC1	O15118-1.2	G679D	Pathogenic	0.819
NPC1	O15118-1.2	G679E	Pathogenic	0.886
NPC1	O15118-1.2	G679F	Pathogenic	0.901
NPC1	O15118-1.2	G679H	Pathogenic	0.907
NPC1	O15118-1.2	G679I	Pathogenic	0.926
NPC1	O15118-1.2	G679K	Pathogenic	0.89
NPC1	O15118-1.2	G679L	Pathogenic	0.928
NPC1	O15118-1.2	G679M	Pathogenic	0.911
NPC1	O15118-1.2	G679N	Pathogenic	0.771
NPC1	O15118-1.2	G679P	Pathogenic	0.871
NPC1	O15118-1.2	G679Q	Pathogenic	0.902
NPC1	O15118-1.2	G679R	Pathogenic	0.897
NPC1	O15118-1.2	G679S	Pathogenic	0.779
NPC1	O15118-1.2	G679T	Pathogenic	0.889
NPC1	O15118-1.2	G679V	Pathogenic	0.902
NPC1	O15118-1.2	G679W	Pathogenic	0.863
NPC1	O15118-1.2	G679Y	Pathogenic	0.926
NPC1	O15118-1.2	L680A	Neutral	0.163
NPC1	O15118-1.2	L680C	Neutral	0.179
NPC1	O15118-1.2	L680D	Neutral	0.273
NPC1	O15118-1.2	L680E	Neutral	0.193
NPC1	O15118-1.2	L680F	Neutral	0.134
NPC1	O15118-1.2	L680G	Neutral	0.386
NPC1	O15118-1.2	L680H	Neutral	0.226
NPC1	O15118-1.2	L680I	Neutral	0.063
NPC1	O15118-1.2	L680K	Neutral	0.124
NPC1	O15118-1.2	L680M	Neutral	0.056
NPC1	O15118-1.2	L680N	Neutral	0.208
NPC1	O15118-1.2	L680P	Neutral	0.296
NPC1	O15118-1.2	L680Q	Neutral	0.154
NPC1	O15118-1.2	L680R	Neutral	0.132
NPC1	O15118-1.2	L680S	Neutral	0.198
NPC1	O15118-1.2	L680T	Neutral	0.141
NPC1	O15118-1.2	L680V	Neutral	0.088
NPC1	O15118-1.2	L680W	Neutral	0.254
NPC1	O15118-1.2	L680Y	Neutral	0.16
NPC1	O15118-1.2	P681A	Pathogenic	0.822
NPC1	O15118-1.2	P681C	Pathogenic	0.903
NPC1	O15118-1.2	P681D	Pathogenic	0.739
NPC1	O15118-1.2	P681E	Pathogenic	0.767
NPC1	O15118-1.2	P681F	Pathogenic	0.931
NPC1	O15118-1.2	P681G	Pathogenic	0.873
NPC1	O15118-1.2	P681H	Pathogenic	0.868
NPC1	O15118-1.2	P681I	Pathogenic	0.895
NPC1	O15118-1.2	P681K	Pathogenic	0.774
NPC1	O15118-1.2	P681L	Pathogenic	0.898
NPC1	O15118-1.2	P681M	Pathogenic	0.875
NPC1	O15118-1.2	P681N	Pathogenic	0.819
NPC1	O15118-1.2	P681Q	Pathogenic	0.796
NPC1	O15118-1.2	P681R	Pathogenic	0.844
NPC1	O15118-1.2	P681S	Pathogenic	0.799
NPC1	O15118-1.2	P681T	Pathogenic	0.801
NPC1	O15118-1.2	P681V	Pathogenic	0.863
NPC1	O15118-1.2	P681W	Pathogenic	0.932
NPC1	O15118-1.2	P681Y	Pathogenic	0.926
NPC1	O15118-1.2	L682A	Neutral	0.284
NPC1	O15118-1.2	L682C	Neutral	0.307
NPC1	O15118-1.2	L682D	Neutral	0.433
NPC1	O15118-1.2	L682E	Neutral	0.327
NPC1	O15118-1.2	L682F	Neutral	0.239
NPC1	O15118-1.2	L682G	Pathogenic	0.561
NPC1	O15118-1.2	L682H	Neutral	0.373
NPC1	O15118-1.2	L682I	Neutral	0.119
NPC1	O15118-1.2	L682K	Neutral	0.223
NPC1	O15118-1.2	L682M	Neutral	0.107
NPC1	O15118-1.2	L682N	Neutral	0.347
NPC1	O15118-1.2	L682P	Neutral	0.461
NPC1	O15118-1.2	L682Q	Neutral	0.269
NPC1	O15118-1.2	L682R	Neutral	0.236
NPC1	O15118-1.2	L682S	Neutral	0.334
NPC1	O15118-1.2	L682T	Neutral	0.25
NPC1	O15118-1.2	L682V	Neutral	0.165
NPC1	O15118-1.2	L682W	Neutral	0.409
NPC1	O15118-1.2	L682Y	Neutral	0.279
NPC1	O15118-1.2	T683A	Pathogenic	0.792
NPC1	O15118-1.2	T683C	Pathogenic	0.799
NPC1	O15118-1.2	T683D	Pathogenic	0.778
NPC1	O15118-1.2	T683E	Pathogenic	0.799
NPC1	O15118-1.2	T683F	Pathogenic	0.847
NPC1	O15118-1.2	T683G	Pathogenic	0.896
NPC1	O15118-1.2	T683H	Pathogenic	0.889
NPC1	O15118-1.2	T683I	Pathogenic	0.778
NPC1	O15118-1.2	T683K	Pathogenic	0.805
NPC1	O15118-1.2	T683L	Pathogenic	0.784
NPC1	O15118-1.2	T683M	Pathogenic	0.809
NPC1	O15118-1.2	T683N	Pathogenic	0.717
NPC1	O15118-1.2	T683P	Pathogenic	0.809
NPC1	O15118-1.2	T683Q	Pathogenic	0.825
NPC1	O15118-1.2	T683R	Pathogenic	0.817
NPC1	O15118-1.2	T683S	Pathogenic	0.697
NPC1	O15118-1.2	T683V	Pathogenic	0.721
NPC1	O15118-1.2	T683W	Pathogenic	0.849
NPC1	O15118-1.2	T683Y	Pathogenic	0.883
NPC1	O15118-1.2	L684A	Pathogenic	0.816
NPC1	O15118-1.2	L684C	Pathogenic	0.832
NPC1	O15118-1.2	L684D	Pathogenic	0.895
NPC1	O15118-1.2	L684E	Pathogenic	0.845
NPC1	O15118-1.2	L684F	Pathogenic	0.779
NPC1	O15118-1.2	L684G	Pathogenic	0.935
NPC1	O15118-1.2	L684H	Pathogenic	0.869
NPC1	O15118-1.2	L684I	Pathogenic	0.603
NPC1	O15118-1.2	L684K	Pathogenic	0.762
NPC1	O15118-1.2	L684M	Pathogenic	0.573
NPC1	O15118-1.2	L684N	Pathogenic	0.856
NPC1	O15118-1.2	L684P	Pathogenic	0.905
NPC1	O15118-1.2	L684Q	Pathogenic	0.805
NPC1	O15118-1.2	L684R	Pathogenic	0.776
NPC1	O15118-1.2	L684S	Pathogenic	0.849
NPC1	O15118-1.2	L684T	Pathogenic	0.788
NPC1	O15118-1.2	L684V	Pathogenic	0.688
NPC1	O15118-1.2	L684W	Pathogenic	0.886
NPC1	O15118-1.2	L684Y	Pathogenic	0.812
NPC1	O15118-1.2	I685A	Pathogenic	0.808
NPC1	O15118-1.2	I685C	Pathogenic	0.824
NPC1	O15118-1.2	I685D	Pathogenic	0.846
NPC1	O15118-1.2	I685E	Pathogenic	0.837
NPC1	O15118-1.2	I685F	Pathogenic	0.78
NPC1	O15118-1.2	I685G	Pathogenic	0.931
NPC1	O15118-1.2	I685H	Pathogenic	0.863
NPC1	O15118-1.2	I685K	Pathogenic	0.817
NPC1	O15118-1.2	I685L	Pathogenic	0.598
NPC1	O15118-1.2	I685M	Pathogenic	0.652
NPC1	O15118-1.2	I685N	Pathogenic	0.849
NPC1	O15118-1.2	I685P	Pathogenic	0.901
NPC1	O15118-1.2	I685Q	Pathogenic	0.852
NPC1	O15118-1.2	I685R	Pathogenic	0.828
NPC1	O15118-1.2	I685S	Pathogenic	0.842
NPC1	O15118-1.2	I685T	Pathogenic	0.779
NPC1	O15118-1.2	I685V	Neutral	0.491
NPC1	O15118-1.2	I685W	Pathogenic	0.92
NPC1	O15118-1.2	I685Y	Pathogenic	0.804
NPC1	O15118-1.2	V686A	Neutral	0.454
NPC1	O15118-1.2	V686C	Pathogenic	0.577
NPC1	O15118-1.2	V686D	Pathogenic	0.615
NPC1	O15118-1.2	V686E	Pathogenic	0.516
NPC1	O15118-1.2	V686F	Pathogenic	0.565
NPC1	O15118-1.2	V686G	Pathogenic	0.728
NPC1	O15118-1.2	V686H	Pathogenic	0.682
NPC1	O15118-1.2	V686I	Neutral	0.206
NPC1	O15118-1.2	V686K	Pathogenic	0.526
NPC1	O15118-1.2	V686L	Neutral	0.367
NPC1	O15118-1.2	V686M	Neutral	0.404
NPC1	O15118-1.2	V686N	Pathogenic	0.621
NPC1	O15118-1.2	V686P	Pathogenic	0.642
NPC1	O15118-1.2	V686Q	Pathogenic	0.558
NPC1	O15118-1.2	V686R	Pathogenic	0.638
NPC1	O15118-1.2	V686S	Pathogenic	0.607
NPC1	O15118-1.2	V686T	Neutral	0.411
NPC1	O15118-1.2	V686W	Pathogenic	0.741
NPC1	O15118-1.2	V686Y	Pathogenic	0.6
NPC1	O15118-1.2	I687A	Pathogenic	0.568
NPC1	O15118-1.2	I687C	Pathogenic	0.595
NPC1	O15118-1.2	I687D	Pathogenic	0.632
NPC1	O15118-1.2	I687E	Pathogenic	0.617
NPC1	O15118-1.2	I687F	Pathogenic	0.526
NPC1	O15118-1.2	I687G	Pathogenic	0.809
NPC1	O15118-1.2	I687H	Pathogenic	0.663
NPC1	O15118-1.2	I687K	Pathogenic	0.583
NPC1	O15118-1.2	I687L	Neutral	0.318
NPC1	O15118-1.2	I687M	Neutral	0.369
NPC1	O15118-1.2	I687N	Pathogenic	0.638
NPC1	O15118-1.2	I687P	Pathogenic	0.739
NPC1	O15118-1.2	I687Q	Pathogenic	0.642
NPC1	O15118-1.2	I687R	Pathogenic	0.601
NPC1	O15118-1.2	I687S	Pathogenic	0.625
NPC1	O15118-1.2	I687T	Pathogenic	0.525
NPC1	O15118-1.2	I687V	Neutral	0.232
NPC1	O15118-1.2	I687W	Pathogenic	0.783
NPC1	O15118-1.2	I687Y	Pathogenic	0.562
NPC1	O15118-1.2	E688A	Pathogenic	0.818
NPC1	O15118-1.2	E688C	Pathogenic	0.911
NPC1	O15118-1.2	E688D	Pathogenic	0.616
NPC1	O15118-1.2	E688F	Pathogenic	0.844
NPC1	O15118-1.2	E688G	Pathogenic	0.892
NPC1	O15118-1.2	E688H	Pathogenic	0.727
NPC1	O15118-1.2	E688I	Pathogenic	0.834
NPC1	O15118-1.2	E688K	Pathogenic	0.697
NPC1	O15118-1.2	E688L	Pathogenic	0.839
NPC1	O15118-1.2	E688M	Pathogenic	0.806
NPC1	O15118-1.2	E688N	Pathogenic	0.777
NPC1	O15118-1.2	E688P	Pathogenic	0.774
NPC1	O15118-1.2	E688Q	Pathogenic	0.574
NPC1	O15118-1.2	E688R	Pathogenic	0.785
NPC1	O15118-1.2	E688S	Pathogenic	0.768
NPC1	O15118-1.2	E688T	Pathogenic	0.797
NPC1	O15118-1.2	E688V	Pathogenic	0.796
NPC1	O15118-1.2	E688W	Pathogenic	0.846
NPC1	O15118-1.2	E688Y	Pathogenic	0.834
NPC1	O15118-1.2	V689A	Pathogenic	0.802
NPC1	O15118-1.2	V689C	Pathogenic	0.869
NPC1	O15118-1.2	V689D	Pathogenic	0.886
NPC1	O15118-1.2	V689E	Pathogenic	0.839
NPC1	O15118-1.2	V689F	Pathogenic	0.864
NPC1	O15118-1.2	V689G	Pathogenic	0.929
NPC1	O15118-1.2	V689H	Pathogenic	0.913
NPC1	O15118-1.2	V689I	Pathogenic	0.558
NPC1	O15118-1.2	V689K	Pathogenic	0.844
NPC1	O15118-1.2	V689L	Pathogenic	0.738
NPC1	O15118-1.2	V689M	Pathogenic	0.767
NPC1	O15118-1.2	V689N	Pathogenic	0.889
NPC1	O15118-1.2	V689P	Pathogenic	0.897
NPC1	O15118-1.2	V689Q	Pathogenic	0.86
NPC1	O15118-1.2	V689R	Pathogenic	0.896
NPC1	O15118-1.2	V689S	Pathogenic	0.883
NPC1	O15118-1.2	V689T	Pathogenic	0.773
NPC1	O15118-1.2	V689W	Pathogenic	0.933
NPC1	O15118-1.2	V689Y	Pathogenic	0.879
NPC1	O15118-1.2	I690A	Pathogenic	0.663
NPC1	O15118-1.2	I690C	Pathogenic	0.687
NPC1	O15118-1.2	I690D	Pathogenic	0.72
NPC1	O15118-1.2	I690E	Pathogenic	0.707
NPC1	O15118-1.2	I690F	Pathogenic	0.624
NPC1	O15118-1.2	I690G	Pathogenic	0.864
NPC1	O15118-1.2	I690H	Pathogenic	0.747
NPC1	O15118-1.2	I690K	Pathogenic	0.677
NPC1	O15118-1.2	I690L	Neutral	0.411
NPC1	O15118-1.2	I690M	Neutral	0.467
NPC1	O15118-1.2	I690N	Pathogenic	0.726
NPC1	O15118-1.2	I690P	Pathogenic	0.81
NPC1	O15118-1.2	I690Q	Pathogenic	0.729
NPC1	O15118-1.2	I690R	Pathogenic	0.693
NPC1	O15118-1.2	I690S	Pathogenic	0.714
NPC1	O15118-1.2	I690T	Pathogenic	0.623
NPC1	O15118-1.2	I690V	Neutral	0.312
NPC1	O15118-1.2	I690W	Pathogenic	0.844
NPC1	O15118-1.2	I690Y	Pathogenic	0.658
NPC1	O15118-1.2	P691A	Pathogenic	0.885
NPC1	O15118-1.2	P691C	Pathogenic	0.94
NPC1	O15118-1.2	P691D	Pathogenic	0.825
NPC1	O15118-1.2	P691E	Pathogenic	0.846
NPC1	O15118-1.2	P691F	Pathogenic	0.957
NPC1	O15118-1.2	P691G	Pathogenic	0.92
NPC1	O15118-1.2	P691H	Pathogenic	0.917
NPC1	O15118-1.2	P691I	Pathogenic	0.934
NPC1	O15118-1.2	P691K	Pathogenic	0.851
NPC1	O15118-1.2	P691L	Pathogenic	0.936
NPC1	O15118-1.2	P691M	Pathogenic	0.921
NPC1	O15118-1.2	P691N	Pathogenic	0.883
NPC1	O15118-1.2	P691Q	Pathogenic	0.867
NPC1	O15118-1.2	P691R	Pathogenic	0.901
NPC1	O15118-1.2	P691S	Pathogenic	0.869
NPC1	O15118-1.2	P691T	Pathogenic	0.87
NPC1	O15118-1.2	P691V	Pathogenic	0.913
NPC1	O15118-1.2	P691W	Pathogenic	0.958
NPC1	O15118-1.2	P691Y	Pathogenic	0.954
NPC1	O15118-1.2	F692A	Pathogenic	0.903
NPC1	O15118-1.2	F692C	Pathogenic	0.912
NPC1	O15118-1.2	F692D	Pathogenic	0.892
NPC1	O15118-1.2	F692E	Pathogenic	0.886
NPC1	O15118-1.2	F692G	Pathogenic	0.933
NPC1	O15118-1.2	F692H	Pathogenic	0.814
NPC1	O15118-1.2	F692I	Pathogenic	0.832
NPC1	O15118-1.2	F692K	Pathogenic	0.855
NPC1	O15118-1.2	F692L	Pathogenic	0.829
NPC1	O15118-1.2	F692M	Pathogenic	0.806
NPC1	O15118-1.2	F692N	Pathogenic	0.895
NPC1	O15118-1.2	F692P	Pathogenic	0.953
NPC1	O15118-1.2	F692Q	Pathogenic	0.896
NPC1	O15118-1.2	F692R	Pathogenic	0.864
NPC1	O15118-1.2	F692S	Pathogenic	0.889
NPC1	O15118-1.2	F692T	Pathogenic	0.887
NPC1	O15118-1.2	F692V	Pathogenic	0.872
NPC1	O15118-1.2	F692W	Pathogenic	0.763
NPC1	O15118-1.2	F692Y	Pathogenic	0.536
NPC1	O15118-1.2	L693A	Pathogenic	0.837
NPC1	O15118-1.2	L693C	Pathogenic	0.852
NPC1	O15118-1.2	L693D	Pathogenic	0.908
NPC1	O15118-1.2	L693E	Pathogenic	0.863
NPC1	O15118-1.2	L693F	Pathogenic	0.803
NPC1	O15118-1.2	L693G	Pathogenic	0.943
NPC1	O15118-1.2	L693H	Pathogenic	0.885
NPC1	O15118-1.2	L693I	Pathogenic	0.638
NPC1	O15118-1.2	L693K	Pathogenic	0.788
NPC1	O15118-1.2	L693M	Pathogenic	0.609
NPC1	O15118-1.2	L693N	Pathogenic	0.874
NPC1	O15118-1.2	L693P	Pathogenic	0.917
NPC1	O15118-1.2	L693Q	Pathogenic	0.827
NPC1	O15118-1.2	L693R	Pathogenic	0.8
NPC1	O15118-1.2	L693S	Pathogenic	0.867
NPC1	O15118-1.2	L693T	Pathogenic	0.812
NPC1	O15118-1.2	L693V	Pathogenic	0.719
NPC1	O15118-1.2	L693W	Pathogenic	0.9
NPC1	O15118-1.2	L693Y	Pathogenic	0.834
NPC1	O15118-1.2	V694A	Pathogenic	0.699
NPC1	O15118-1.2	V694C	Pathogenic	0.792
NPC1	O15118-1.2	V694D	Pathogenic	0.817
NPC1	O15118-1.2	V694E	Pathogenic	0.749
NPC1	O15118-1.2	V694F	Pathogenic	0.785
NPC1	O15118-1.2	V694G	Pathogenic	0.882
NPC1	O15118-1.2	V694H	Pathogenic	0.857
NPC1	O15118-1.2	V694I	Neutral	0.42
NPC1	O15118-1.2	V694K	Pathogenic	0.757
NPC1	O15118-1.2	V694L	Pathogenic	0.619
NPC1	O15118-1.2	V694M	Pathogenic	0.655
NPC1	O15118-1.2	V694N	Pathogenic	0.821
NPC1	O15118-1.2	V694P	Pathogenic	0.834
NPC1	O15118-1.2	V694Q	Pathogenic	0.78
NPC1	O15118-1.2	V694R	Pathogenic	0.831
NPC1	O15118-1.2	V694S	Pathogenic	0.812
NPC1	O15118-1.2	V694T	Pathogenic	0.661
NPC1	O15118-1.2	V694W	Pathogenic	0.889
NPC1	O15118-1.2	V694Y	Pathogenic	0.808
NPC1	O15118-1.2	L695A	Pathogenic	0.837
NPC1	O15118-1.2	L695C	Pathogenic	0.852
NPC1	O15118-1.2	L695D	Pathogenic	0.908
NPC1	O15118-1.2	L695E	Pathogenic	0.863
NPC1	O15118-1.2	L695F	Pathogenic	0.803
NPC1	O15118-1.2	L695G	Pathogenic	0.943
NPC1	O15118-1.2	L695H	Pathogenic	0.885
NPC1	O15118-1.2	L695I	Pathogenic	0.638
NPC1	O15118-1.2	L695K	Pathogenic	0.788
NPC1	O15118-1.2	L695M	Pathogenic	0.609
NPC1	O15118-1.2	L695N	Pathogenic	0.874
NPC1	O15118-1.2	L695P	Pathogenic	0.917
NPC1	O15118-1.2	L695Q	Pathogenic	0.827
NPC1	O15118-1.2	L695R	Pathogenic	0.8
NPC1	O15118-1.2	L695S	Pathogenic	0.867
NPC1	O15118-1.2	L695T	Pathogenic	0.812
NPC1	O15118-1.2	L695V	Pathogenic	0.719
NPC1	O15118-1.2	L695W	Pathogenic	0.9
NPC1	O15118-1.2	L695Y	Pathogenic	0.834
NPC1	O15118-1.2	A696C	Pathogenic	0.809
NPC1	O15118-1.2	A696D	Pathogenic	0.892
NPC1	O15118-1.2	A696E	Pathogenic	0.867
NPC1	O15118-1.2	A696F	Pathogenic	0.904
NPC1	O15118-1.2	A696G	Pathogenic	0.827
NPC1	O15118-1.2	A696H	Pathogenic	0.929
NPC1	O15118-1.2	A696I	Pathogenic	0.856
NPC1	O15118-1.2	A696K	Pathogenic	0.872
NPC1	O15118-1.2	A696L	Pathogenic	0.861
NPC1	O15118-1.2	A696M	Pathogenic	0.878
NPC1	O15118-1.2	A696N	Pathogenic	0.9
NPC1	O15118-1.2	A696P	Pathogenic	0.874
NPC1	O15118-1.2	A696Q	Pathogenic	0.886
NPC1	O15118-1.2	A696R	Pathogenic	0.88
NPC1	O15118-1.2	A696S	Pathogenic	0.748
NPC1	O15118-1.2	A696T	Pathogenic	0.845
NPC1	O15118-1.2	A696V	Pathogenic	0.815
NPC1	O15118-1.2	A696W	Pathogenic	0.934
NPC1	O15118-1.2	A696Y	Pathogenic	0.928
NPC1	O15118-1.2	V697A	Pathogenic	0.688
NPC1	O15118-1.2	V697C	Pathogenic	0.783
NPC1	O15118-1.2	V697D	Pathogenic	0.809
NPC1	O15118-1.2	V697E	Pathogenic	0.739
NPC1	O15118-1.2	V697F	Pathogenic	0.775
NPC1	O15118-1.2	V697G	Pathogenic	0.876
NPC1	O15118-1.2	V697H	Pathogenic	0.85
NPC1	O15118-1.2	V697I	Neutral	0.407
NPC1	O15118-1.2	V697K	Pathogenic	0.747
NPC1	O15118-1.2	V697L	Pathogenic	0.606
NPC1	O15118-1.2	V697M	Pathogenic	0.642
NPC1	O15118-1.2	V697N	Pathogenic	0.813
NPC1	O15118-1.2	V697P	Pathogenic	0.826
NPC1	O15118-1.2	V697Q	Pathogenic	0.77
NPC1	O15118-1.2	V697R	Pathogenic	0.823
NPC1	O15118-1.2	V697S	Pathogenic	0.804
NPC1	O15118-1.2	V697T	Pathogenic	0.649
NPC1	O15118-1.2	V697W	Pathogenic	0.883
NPC1	O15118-1.2	V697Y	Pathogenic	0.799
NPC1	O15118-1.2	G698A	Pathogenic	0.828
NPC1	O15118-1.2	G698C	Pathogenic	0.932
NPC1	O15118-1.2	G698D	Pathogenic	0.875
NPC1	O15118-1.2	G698E	Pathogenic	0.923
NPC1	O15118-1.2	G698F	Pathogenic	0.934
NPC1	O15118-1.2	G698H	Pathogenic	0.937
NPC1	O15118-1.2	G698I	Pathogenic	0.951
NPC1	O15118-1.2	G698K	Pathogenic	0.926
NPC1	O15118-1.2	G698L	Pathogenic	0.952
NPC1	O15118-1.2	G698M	Pathogenic	0.941
NPC1	O15118-1.2	G698N	Pathogenic	0.838
NPC1	O15118-1.2	G698P	Pathogenic	0.912
NPC1	O15118-1.2	G698Q	Pathogenic	0.934
NPC1	O15118-1.2	G698R	Pathogenic	0.931
NPC1	O15118-1.2	G698S	Pathogenic	0.845
NPC1	O15118-1.2	G698T	Pathogenic	0.925
NPC1	O15118-1.2	G698V	Pathogenic	0.934
NPC1	O15118-1.2	G698W	Pathogenic	0.907
NPC1	O15118-1.2	G698Y	Pathogenic	0.951
NPC1	O15118-1.2	V699A	Pathogenic	0.901
NPC1	O15118-1.2	V699C	Pathogenic	0.937
NPC1	O15118-1.2	V699D	Pathogenic	0.946
NPC1	O15118-1.2	V699E	Pathogenic	0.922
NPC1	O15118-1.2	V699F	Pathogenic	0.935
NPC1	O15118-1.2	V699G	Pathogenic	0.967
NPC1	O15118-1.2	V699H	Pathogenic	0.959
NPC1	O15118-1.2	V699I	Pathogenic	0.74
NPC1	O15118-1.2	V699K	Pathogenic	0.924
NPC1	O15118-1.2	V699L	Pathogenic	0.864
NPC1	O15118-1.2	V699M	Pathogenic	0.882
NPC1	O15118-1.2	V699N	Pathogenic	0.947
NPC1	O15118-1.2	V699P	Pathogenic	0.952
NPC1	O15118-1.2	V699Q	Pathogenic	0.933
NPC1	O15118-1.2	V699R	Pathogenic	0.951
NPC1	O15118-1.2	V699S	Pathogenic	0.944
NPC1	O15118-1.2	V699T	Pathogenic	0.885
NPC1	O15118-1.2	V699W	Pathogenic	0.969
NPC1	O15118-1.2	V699Y	Pathogenic	0.943
NPC1	O15118-1.2	D700A	Pathogenic	0.973
NPC1	O15118-1.2	D700C	Pathogenic	0.974
NPC1	O15118-1.2	D700E	Pathogenic	0.911
NPC1	O15118-1.2	D700F	Pathogenic	0.973
NPC1	O15118-1.2	D700G	Pathogenic	0.968
NPC1	O15118-1.2	D700H	Pathogenic	0.964
NPC1	O15118-1.2	D700I	Pathogenic	0.972
NPC1	O15118-1.2	D700K	Pathogenic	0.974
NPC1	O15118-1.2	D700L	Pathogenic	0.981
NPC1	O15118-1.2	D700M	Pathogenic	0.976
NPC1	O15118-1.2	D700N	Pathogenic	0.932
NPC1	O15118-1.2	D700P	Pathogenic	0.949
NPC1	O15118-1.2	D700Q	Pathogenic	0.952
NPC1	O15118-1.2	D700R	Pathogenic	0.983
NPC1	O15118-1.2	D700S	Pathogenic	0.948
NPC1	O15118-1.2	D700T	Pathogenic	0.956
NPC1	O15118-1.2	D700V	Pathogenic	0.974
NPC1	O15118-1.2	D700W	Pathogenic	0.982
NPC1	O15118-1.2	D700Y	Pathogenic	0.98
NPC1	O15118-1.2	N701A	Pathogenic	0.97
NPC1	O15118-1.2	N701C	Pathogenic	0.972
NPC1	O15118-1.2	N701D	Pathogenic	0.919
NPC1	O15118-1.2	N701E	Pathogenic	0.948
NPC1	O15118-1.2	N701F	Pathogenic	0.969
NPC1	O15118-1.2	N701G	Pathogenic	0.949
NPC1	O15118-1.2	N701H	Pathogenic	0.913
NPC1	O15118-1.2	N701I	Pathogenic	0.967
NPC1	O15118-1.2	N701K	Pathogenic	0.95
NPC1	O15118-1.2	N701L	Pathogenic	0.968
NPC1	O15118-1.2	N701M	Pathogenic	0.96
NPC1	O15118-1.2	N701P	Pathogenic	0.961
NPC1	O15118-1.2	N701Q	Pathogenic	0.944
NPC1	O15118-1.2	N701R	Pathogenic	0.954
NPC1	O15118-1.2	N701S	Pathogenic	0.917
NPC1	O15118-1.2	N701T	Pathogenic	0.929
NPC1	O15118-1.2	N701V	Pathogenic	0.969
NPC1	O15118-1.2	N701W	Pathogenic	0.979
NPC1	O15118-1.2	N701Y	Pathogenic	0.967
NPC1	O15118-1.2	I702A	Pathogenic	0.926
NPC1	O15118-1.2	I702C	Pathogenic	0.933
NPC1	O15118-1.2	I702D	Pathogenic	0.942
NPC1	O15118-1.2	I702E	Pathogenic	0.938
NPC1	O15118-1.2	I702F	Pathogenic	0.913
NPC1	O15118-1.2	I702G	Pathogenic	0.976
NPC1	O15118-1.2	I702H	Pathogenic	0.949
NPC1	O15118-1.2	I702K	Pathogenic	0.93
NPC1	O15118-1.2	I702L	Pathogenic	0.815
NPC1	O15118-1.2	I702M	Pathogenic	0.847
NPC1	O15118-1.2	I702N	Pathogenic	0.943
NPC1	O15118-1.2	I702P	Pathogenic	0.964
NPC1	O15118-1.2	I702Q	Pathogenic	0.944
NPC1	O15118-1.2	I702R	Pathogenic	0.934
NPC1	O15118-1.2	I702S	Pathogenic	0.94
NPC1	O15118-1.2	I702T	Pathogenic	0.913
NPC1	O15118-1.2	I702V	Pathogenic	0.741
NPC1	O15118-1.2	I702W	Pathogenic	0.972
NPC1	O15118-1.2	I702Y	Pathogenic	0.924
NPC1	O15118-1.2	F703A	Pathogenic	0.972
NPC1	O15118-1.2	F703C	Pathogenic	0.975
NPC1	O15118-1.2	F703D	Pathogenic	0.968
NPC1	O15118-1.2	F703E	Pathogenic	0.966
NPC1	O15118-1.2	F703G	Pathogenic	0.981
NPC1	O15118-1.2	F703H	Pathogenic	0.942
NPC1	O15118-1.2	F703I	Pathogenic	0.948
NPC1	O15118-1.2	F703K	Pathogenic	0.956
NPC1	O15118-1.2	F703L	Pathogenic	0.947
NPC1	O15118-1.2	F703M	Pathogenic	0.939
NPC1	O15118-1.2	F703N	Pathogenic	0.969
NPC1	O15118-1.2	F703P	Pathogenic	0.987
NPC1	O15118-1.2	F703Q	Pathogenic	0.97
NPC1	O15118-1.2	F703R	Pathogenic	0.959
NPC1	O15118-1.2	F703S	Pathogenic	0.967
NPC1	O15118-1.2	F703T	Pathogenic	0.967
NPC1	O15118-1.2	F703V	Pathogenic	0.962
NPC1	O15118-1.2	F703W	Pathogenic	0.922
NPC1	O15118-1.2	F703Y	Pathogenic	0.81
NPC1	O15118-1.2	I704A	Pathogenic	0.959
NPC1	O15118-1.2	I704C	Pathogenic	0.963
NPC1	O15118-1.2	I704D	Pathogenic	0.969
NPC1	O15118-1.2	I704E	Pathogenic	0.967
NPC1	O15118-1.2	I704F	Pathogenic	0.952
NPC1	O15118-1.2	I704G	Pathogenic	0.987
NPC1	O15118-1.2	I704H	Pathogenic	0.972
NPC1	O15118-1.2	I704K	Pathogenic	0.962
NPC1	O15118-1.2	I704L	Pathogenic	0.893
NPC1	O15118-1.2	I704M	Pathogenic	0.913
NPC1	O15118-1.2	I704N	Pathogenic	0.969
NPC1	O15118-1.2	I704P	Pathogenic	0.981
NPC1	O15118-1.2	I704Q	Pathogenic	0.97
NPC1	O15118-1.2	I704R	Pathogenic	0.964
NPC1	O15118-1.2	I704S	Pathogenic	0.968
NPC1	O15118-1.2	I704T	Pathogenic	0.952
NPC1	O15118-1.2	I704V	Pathogenic	0.844
NPC1	O15118-1.2	I704W	Pathogenic	0.985
NPC1	O15118-1.2	I704Y	Pathogenic	0.958
NPC1	O15118-1.2	L705A	Pathogenic	0.742
NPC1	O15118-1.2	L705C	Pathogenic	0.763
NPC1	O15118-1.2	L705D	Pathogenic	0.847
NPC1	O15118-1.2	L705E	Pathogenic	0.779
NPC1	O15118-1.2	L705F	Pathogenic	0.696
NPC1	O15118-1.2	L705G	Pathogenic	0.903
NPC1	O15118-1.2	L705H	Pathogenic	0.812
NPC1	O15118-1.2	L705I	Neutral	0.496
NPC1	O15118-1.2	L705K	Pathogenic	0.676
NPC1	O15118-1.2	L705M	Neutral	0.466
NPC1	O15118-1.2	L705N	Pathogenic	0.794
NPC1	O15118-1.2	L705P	Pathogenic	0.861
NPC1	O15118-1.2	L705Q	Pathogenic	0.728
NPC1	O15118-1.2	L705R	Pathogenic	0.692
NPC1	O15118-1.2	L705S	Pathogenic	0.785
NPC1	O15118-1.2	L705T	Pathogenic	0.708
NPC1	O15118-1.2	L705V	Pathogenic	0.589
NPC1	O15118-1.2	L705W	Pathogenic	0.834
NPC1	O15118-1.2	L705Y	Pathogenic	0.737
NPC1	O15118-1.2	V706A	Pathogenic	0.934
NPC1	O15118-1.2	V706C	Pathogenic	0.959
NPC1	O15118-1.2	V706D	Pathogenic	0.965
NPC1	O15118-1.2	V706E	Pathogenic	0.948
NPC1	O15118-1.2	V706F	Pathogenic	0.957
NPC1	O15118-1.2	V706G	Pathogenic	0.979
NPC1	O15118-1.2	V706H	Pathogenic	0.973
NPC1	O15118-1.2	V706I	Pathogenic	0.816
NPC1	O15118-1.2	V706K	Pathogenic	0.95
NPC1	O15118-1.2	V706L	Pathogenic	0.908
NPC1	O15118-1.2	V706M	Pathogenic	0.92
NPC1	O15118-1.2	V706N	Pathogenic	0.966
NPC1	O15118-1.2	V706P	Pathogenic	0.968
NPC1	O15118-1.2	V706Q	Pathogenic	0.956
NPC1	O15118-1.2	V706R	Pathogenic	0.968
NPC1	O15118-1.2	V706S	Pathogenic	0.963
NPC1	O15118-1.2	V706T	Pathogenic	0.923
NPC1	O15118-1.2	V706W	Pathogenic	0.98
NPC1	O15118-1.2	V706Y	Pathogenic	0.962
NPC1	O15118-1.2	Q707A	Pathogenic	0.958
NPC1	O15118-1.2	Q707C	Pathogenic	0.972
NPC1	O15118-1.2	Q707D	Pathogenic	0.929
NPC1	O15118-1.2	Q707E	Pathogenic	0.851
NPC1	O15118-1.2	Q707F	Pathogenic	0.962
NPC1	O15118-1.2	Q707G	Pathogenic	0.976
NPC1	O15118-1.2	Q707H	Pathogenic	0.926
NPC1	O15118-1.2	Q707I	Pathogenic	0.96
NPC1	O15118-1.2	Q707K	Pathogenic	0.891
NPC1	O15118-1.2	Q707L	Pathogenic	0.943
NPC1	O15118-1.2	Q707M	Pathogenic	0.9
NPC1	O15118-1.2	Q707N	Pathogenic	0.931
NPC1	O15118-1.2	Q707P	Pathogenic	0.945
NPC1	O15118-1.2	Q707R	Pathogenic	0.898
NPC1	O15118-1.2	Q707S	Pathogenic	0.943
NPC1	O15118-1.2	Q707T	Pathogenic	0.951
NPC1	O15118-1.2	Q707V	Pathogenic	0.951
NPC1	O15118-1.2	Q707W	Pathogenic	0.946
NPC1	O15118-1.2	Q707Y	Pathogenic	0.941
NPC1	O15118-1.2	A708C	Neutral	0.492
NPC1	O15118-1.2	A708D	Pathogenic	0.654
NPC1	O15118-1.2	A708E	Pathogenic	0.599
NPC1	O15118-1.2	A708F	Pathogenic	0.683
NPC1	O15118-1.2	A708G	Pathogenic	0.522
NPC1	O15118-1.2	A708H	Pathogenic	0.75
NPC1	O15118-1.2	A708I	Pathogenic	0.577
NPC1	O15118-1.2	A708K	Pathogenic	0.609
NPC1	O15118-1.2	A708L	Pathogenic	0.585
NPC1	O15118-1.2	A708M	Pathogenic	0.622
NPC1	O15118-1.2	A708N	Pathogenic	0.673
NPC1	O15118-1.2	A708P	Pathogenic	0.614
NPC1	O15118-1.2	A708Q	Pathogenic	0.639
NPC1	O15118-1.2	A708R	Pathogenic	0.626
NPC1	O15118-1.2	A708S	Neutral	0.404
NPC1	O15118-1.2	A708T	Pathogenic	0.554
NPC1	O15118-1.2	A708V	Pathogenic	0.501
NPC1	O15118-1.2	A708W	Pathogenic	0.763
NPC1	O15118-1.2	A708Y	Pathogenic	0.746
NPC1	O15118-1.2	Y709A	Pathogenic	0.83
NPC1	O15118-1.2	Y709C	Pathogenic	0.843
NPC1	O15118-1.2	Y709D	Pathogenic	0.812
NPC1	O15118-1.2	Y709E	Pathogenic	0.734
NPC1	O15118-1.2	Y709F	Neutral	0.307
NPC1	O15118-1.2	Y709G	Pathogenic	0.879
NPC1	O15118-1.2	Y709H	Neutral	0.419
NPC1	O15118-1.2	Y709I	Pathogenic	0.688
NPC1	O15118-1.2	Y709K	Pathogenic	0.677
NPC1	O15118-1.2	Y709L	Pathogenic	0.695
NPC1	O15118-1.2	Y709M	Pathogenic	0.727
NPC1	O15118-1.2	Y709N	Pathogenic	0.751
NPC1	O15118-1.2	Y709P	Pathogenic	0.877
NPC1	O15118-1.2	Y709Q	Pathogenic	0.676
NPC1	O15118-1.2	Y709R	Pathogenic	0.677
NPC1	O15118-1.2	Y709S	Pathogenic	0.807
NPC1	O15118-1.2	Y709T	Pathogenic	0.803
NPC1	O15118-1.2	Y709V	Pathogenic	0.75
NPC1	O15118-1.2	Y709W	Neutral	0.381
NPC1	O15118-1.2	Q710A	Pathogenic	0.971
NPC1	O15118-1.2	Q710C	Pathogenic	0.981
NPC1	O15118-1.2	Q710D	Pathogenic	0.951
NPC1	O15118-1.2	Q710E	Pathogenic	0.893
NPC1	O15118-1.2	Q710F	Pathogenic	0.974
NPC1	O15118-1.2	Q710G	Pathogenic	0.984
NPC1	O15118-1.2	Q710H	Pathogenic	0.948
NPC1	O15118-1.2	Q710I	Pathogenic	0.972
NPC1	O15118-1.2	Q710K	Pathogenic	0.923
NPC1	O15118-1.2	Q710L	Pathogenic	0.961
NPC1	O15118-1.2	Q710M	Pathogenic	0.929
NPC1	O15118-1.2	Q710N	Pathogenic	0.952
NPC1	O15118-1.2	Q710P	Pathogenic	0.962
NPC1	O15118-1.2	Q710R	Pathogenic	0.928
NPC1	O15118-1.2	Q710S	Pathogenic	0.96
NPC1	O15118-1.2	Q710T	Pathogenic	0.966
NPC1	O15118-1.2	Q710V	Pathogenic	0.966
NPC1	O15118-1.2	Q710W	Pathogenic	0.963
NPC1	O15118-1.2	Q710Y	Pathogenic	0.959
NPC1	O15118-1.2	R711A	Pathogenic	0.962
NPC1	O15118-1.2	R711C	Pathogenic	0.975
NPC1	O15118-1.2	R711D	Pathogenic	0.979
NPC1	O15118-1.2	R711E	Pathogenic	0.948
NPC1	O15118-1.2	R711F	Pathogenic	0.956
NPC1	O15118-1.2	R711G	Pathogenic	0.979
NPC1	O15118-1.2	R711H	Pathogenic	0.93
NPC1	O15118-1.2	R711I	Pathogenic	0.959
NPC1	O15118-1.2	R711K	Pathogenic	0.889
NPC1	O15118-1.2	R711L	Pathogenic	0.943
NPC1	O15118-1.2	R711M	Pathogenic	0.929
NPC1	O15118-1.2	R711N	Pathogenic	0.951
NPC1	O15118-1.2	R711P	Pathogenic	0.965
NPC1	O15118-1.2	R711Q	Pathogenic	0.912
NPC1	O15118-1.2	R711S	Pathogenic	0.964
NPC1	O15118-1.2	R711T	Pathogenic	0.956
NPC1	O15118-1.2	R711V	Pathogenic	0.97
NPC1	O15118-1.2	R711W	Pathogenic	0.95
NPC1	O15118-1.2	R711Y	Pathogenic	0.95
NPC1	O15118-1.2	D712A	Pathogenic	0.769
NPC1	O15118-1.2	D712C	Pathogenic	0.777
NPC1	O15118-1.2	D712E	Neutral	0.484
NPC1	O15118-1.2	D712F	Pathogenic	0.772
NPC1	O15118-1.2	D712G	Pathogenic	0.738
NPC1	O15118-1.2	D712H	Pathogenic	0.71
NPC1	O15118-1.2	D712I	Pathogenic	0.759
NPC1	O15118-1.2	D712K	Pathogenic	0.773
NPC1	O15118-1.2	D712L	Pathogenic	0.827
NPC1	O15118-1.2	D712M	Pathogenic	0.792
NPC1	O15118-1.2	D712N	Pathogenic	0.558
NPC1	O15118-1.2	D712P	Pathogenic	0.632
NPC1	O15118-1.2	D712Q	Pathogenic	0.646
NPC1	O15118-1.2	D712R	Pathogenic	0.843
NPC1	O15118-1.2	D712S	Pathogenic	0.625
NPC1	O15118-1.2	D712T	Pathogenic	0.668
NPC1	O15118-1.2	D712V	Pathogenic	0.773
NPC1	O15118-1.2	D712W	Pathogenic	0.835
NPC1	O15118-1.2	D712Y	Pathogenic	0.822
NPC1	O15118-1.2	E713A	Neutral	0.416
NPC1	O15118-1.2	E713C	Pathogenic	0.618
NPC1	O15118-1.2	E713D	Neutral	0.203
NPC1	O15118-1.2	E713F	Neutral	0.461
NPC1	O15118-1.2	E713G	Pathogenic	0.566
NPC1	O15118-1.2	E713H	Neutral	0.296
NPC1	O15118-1.2	E713I	Neutral	0.444
NPC1	O15118-1.2	E713K	Neutral	0.267
NPC1	O15118-1.2	E713L	Neutral	0.452
NPC1	O15118-1.2	E713M	Neutral	0.396
NPC1	O15118-1.2	E713N	Neutral	0.355
NPC1	O15118-1.2	E713P	Neutral	0.351
NPC1	O15118-1.2	E713Q	Neutral	0.176
NPC1	O15118-1.2	E713R	Neutral	0.366
NPC1	O15118-1.2	E713S	Neutral	0.344
NPC1	O15118-1.2	E713T	Neutral	0.383
NPC1	O15118-1.2	E713V	Neutral	0.381
NPC1	O15118-1.2	E713W	Neutral	0.465
NPC1	O15118-1.2	E713Y	Neutral	0.443
NPC1	O15118-1.2	R714A	Pathogenic	0.889
NPC1	O15118-1.2	R714C	Pathogenic	0.925
NPC1	O15118-1.2	R714D	Pathogenic	0.936
NPC1	O15118-1.2	R714E	Pathogenic	0.853
NPC1	O15118-1.2	R714F	Pathogenic	0.876
NPC1	O15118-1.2	R714G	Pathogenic	0.936
NPC1	O15118-1.2	R714H	Pathogenic	0.81
NPC1	O15118-1.2	R714I	Pathogenic	0.882
NPC1	O15118-1.2	R714K	Pathogenic	0.72
NPC1	O15118-1.2	R714L	Pathogenic	0.841
NPC1	O15118-1.2	R714M	Pathogenic	0.807
NPC1	O15118-1.2	R714N	Pathogenic	0.861
NPC1	O15118-1.2	R714P	Pathogenic	0.9
NPC1	O15118-1.2	R714Q	Pathogenic	0.769
NPC1	O15118-1.2	R714S	Pathogenic	0.897
NPC1	O15118-1.2	R714T	Pathogenic	0.875
NPC1	O15118-1.2	R714V	Pathogenic	0.911
NPC1	O15118-1.2	R714W	Pathogenic	0.859
NPC1	O15118-1.2	R714Y	Pathogenic	0.859
NPC1	O15118-1.2	L715A	Neutral	0.328
NPC1	O15118-1.2	L715C	Neutral	0.353
NPC1	O15118-1.2	L715D	Neutral	0.485
NPC1	O15118-1.2	L715E	Neutral	0.375
NPC1	O15118-1.2	L715F	Neutral	0.28
NPC1	O15118-1.2	L715G	Pathogenic	0.612
NPC1	O15118-1.2	L715H	Neutral	0.423
NPC1	O15118-1.2	L715I	Neutral	0.143
NPC1	O15118-1.2	L715K	Neutral	0.261
NPC1	O15118-1.2	L715M	Neutral	0.129
NPC1	O15118-1.2	L715N	Neutral	0.396
NPC1	O15118-1.2	L715P	Pathogenic	0.513
NPC1	O15118-1.2	L715Q	Neutral	0.312
NPC1	O15118-1.2	L715R	Neutral	0.276
NPC1	O15118-1.2	L715S	Neutral	0.382
NPC1	O15118-1.2	L715T	Neutral	0.291
NPC1	O15118-1.2	L715V	Neutral	0.196
NPC1	O15118-1.2	L715W	Neutral	0.461
NPC1	O15118-1.2	L715Y	Neutral	0.323
NPC1	O15118-1.2	Q716A	Pathogenic	0.577
NPC1	O15118-1.2	Q716C	Pathogenic	0.678
NPC1	O15118-1.2	Q716D	Neutral	0.444
NPC1	O15118-1.2	Q716E	Neutral	0.257
NPC1	O15118-1.2	Q716F	Pathogenic	0.607
NPC1	O15118-1.2	Q716G	Pathogenic	0.714
NPC1	O15118-1.2	Q716H	Neutral	0.432
NPC1	O15118-1.2	Q716I	Pathogenic	0.59
NPC1	O15118-1.2	Q716K	Neutral	0.332
NPC1	O15118-1.2	Q716L	Pathogenic	0.503
NPC1	O15118-1.2	Q716M	Neutral	0.353
NPC1	O15118-1.2	Q716N	Neutral	0.45
NPC1	O15118-1.2	Q716P	Pathogenic	0.509
NPC1	O15118-1.2	Q716R	Neutral	0.349
NPC1	O15118-1.2	Q716S	Pathogenic	0.501
NPC1	O15118-1.2	Q716T	Pathogenic	0.543
NPC1	O15118-1.2	Q716V	Pathogenic	0.541
NPC1	O15118-1.2	Q716W	Pathogenic	0.516
NPC1	O15118-1.2	Q716Y	Neutral	0.494
NPC1	O15118-1.2	G717A	Neutral	0.297
NPC1	O15118-1.2	G717C	Pathogenic	0.547
NPC1	O15118-1.2	G717D	Neutral	0.381
NPC1	O15118-1.2	G717E	Pathogenic	0.514
NPC1	O15118-1.2	G717F	Pathogenic	0.554
NPC1	O15118-1.2	G717H	Pathogenic	0.569
NPC1	O15118-1.2	G717I	Pathogenic	0.629
NPC1	O15118-1.2	G717K	Pathogenic	0.524
NPC1	O15118-1.2	G717L	Pathogenic	0.637
NPC1	O15118-1.2	G717M	Pathogenic	0.583
NPC1	O15118-1.2	G717N	Neutral	0.314
NPC1	O15118-1.2	G717P	Neutral	0.478
NPC1	O15118-1.2	G717Q	Pathogenic	0.556
NPC1	O15118-1.2	G717R	Pathogenic	0.542
NPC1	O15118-1.2	G717S	Neutral	0.324
NPC1	O15118-1.2	G717T	Pathogenic	0.521
NPC1	O15118-1.2	G717V	Pathogenic	0.556
NPC1	O15118-1.2	G717W	Neutral	0.461
NPC1	O15118-1.2	G717Y	Pathogenic	0.629
NPC1	O15118-1.2	E718A	Pathogenic	0.951
NPC1	O15118-1.2	E718C	Pathogenic	0.978
NPC1	O15118-1.2	E718D	Pathogenic	0.873
NPC1	O15118-1.2	E718F	Pathogenic	0.959
NPC1	O15118-1.2	E718G	Pathogenic	0.972
NPC1	O15118-1.2	E718H	Pathogenic	0.919
NPC1	O15118-1.2	E718I	Pathogenic	0.956
NPC1	O15118-1.2	E718K	Pathogenic	0.908
NPC1	O15118-1.2	E718L	Pathogenic	0.957
NPC1	O15118-1.2	E718M	Pathogenic	0.947
NPC1	O15118-1.2	E718N	Pathogenic	0.937
NPC1	O15118-1.2	E718P	Pathogenic	0.936
NPC1	O15118-1.2	E718Q	Pathogenic	0.852
NPC1	O15118-1.2	E718R	Pathogenic	0.94
NPC1	O15118-1.2	E718S	Pathogenic	0.934
NPC1	O15118-1.2	E718T	Pathogenic	0.944
NPC1	O15118-1.2	E718V	Pathogenic	0.943
NPC1	O15118-1.2	E718W	Pathogenic	0.959
NPC1	O15118-1.2	E718Y	Pathogenic	0.956
NPC1	O15118-1.2	T719A	Pathogenic	0.601
NPC1	O15118-1.2	T719C	Pathogenic	0.612
NPC1	O15118-1.2	T719D	Pathogenic	0.58
NPC1	O15118-1.2	T719E	Pathogenic	0.611
NPC1	O15118-1.2	T719F	Pathogenic	0.687
NPC1	O15118-1.2	T719G	Pathogenic	0.773
NPC1	O15118-1.2	T719H	Pathogenic	0.759
NPC1	O15118-1.2	T719I	Pathogenic	0.581
NPC1	O15118-1.2	T719K	Pathogenic	0.621
NPC1	O15118-1.2	T719L	Pathogenic	0.589
NPC1	O15118-1.2	T719M	Pathogenic	0.626
NPC1	O15118-1.2	T719N	Pathogenic	0.5
NPC1	O15118-1.2	T719P	Pathogenic	0.627
NPC1	O15118-1.2	T719Q	Pathogenic	0.651
NPC1	O15118-1.2	T719R	Pathogenic	0.638
NPC1	O15118-1.2	T719S	Neutral	0.476
NPC1	O15118-1.2	T719V	Pathogenic	0.505
NPC1	O15118-1.2	T719W	Pathogenic	0.69
NPC1	O15118-1.2	T719Y	Pathogenic	0.75
NPC1	O15118-1.2	L720A	Neutral	0.427
NPC1	O15118-1.2	L720C	Neutral	0.454
NPC1	O15118-1.2	L720D	Pathogenic	0.589
NPC1	O15118-1.2	L720E	Neutral	0.477
NPC1	O15118-1.2	L720F	Neutral	0.372
NPC1	O15118-1.2	L720G	Pathogenic	0.706
NPC1	O15118-1.2	L720H	Pathogenic	0.528
NPC1	O15118-1.2	L720I	Neutral	0.203
NPC1	O15118-1.2	L720K	Neutral	0.35
NPC1	O15118-1.2	L720M	Neutral	0.184
NPC1	O15118-1.2	L720N	Pathogenic	0.5
NPC1	O15118-1.2	L720P	Pathogenic	0.617
NPC1	O15118-1.2	L720Q	Neutral	0.409
NPC1	O15118-1.2	L720R	Neutral	0.367
NPC1	O15118-1.2	L720S	Neutral	0.485
NPC1	O15118-1.2	L720T	Neutral	0.385
NPC1	O15118-1.2	L720V	Neutral	0.27
NPC1	O15118-1.2	L720W	Pathogenic	0.566
NPC1	O15118-1.2	L720Y	Neutral	0.421
NPC1	O15118-1.2	D721A	Pathogenic	0.545
NPC1	O15118-1.2	D721C	Pathogenic	0.557
NPC1	O15118-1.2	D721E	Neutral	0.253
NPC1	O15118-1.2	D721F	Pathogenic	0.549
NPC1	O15118-1.2	D721G	Pathogenic	0.503
NPC1	O15118-1.2	D721H	Neutral	0.468
NPC1	O15118-1.2	D721I	Pathogenic	0.531
NPC1	O15118-1.2	D721K	Pathogenic	0.55
NPC1	O15118-1.2	D721L	Pathogenic	0.633
NPC1	O15118-1.2	D721M	Pathogenic	0.578
NPC1	O15118-1.2	D721N	Neutral	0.313
NPC1	O15118-1.2	D721P	Neutral	0.382
NPC1	O15118-1.2	D721Q	Neutral	0.396
NPC1	O15118-1.2	D721R	Pathogenic	0.66
NPC1	O15118-1.2	D721S	Neutral	0.375
NPC1	O15118-1.2	D721T	Neutral	0.421
NPC1	O15118-1.2	D721V	Pathogenic	0.551
NPC1	O15118-1.2	D721W	Pathogenic	0.645
NPC1	O15118-1.2	D721Y	Pathogenic	0.624
NPC1	O15118-1.2	Q722A	Pathogenic	0.564
NPC1	O15118-1.2	Q722C	Pathogenic	0.666
NPC1	O15118-1.2	Q722D	Neutral	0.43
NPC1	O15118-1.2	Q722E	Neutral	0.247
NPC1	O15118-1.2	Q722F	Pathogenic	0.594
NPC1	O15118-1.2	Q722G	Pathogenic	0.703
NPC1	O15118-1.2	Q722H	Neutral	0.418
NPC1	O15118-1.2	Q722I	Pathogenic	0.576
NPC1	O15118-1.2	Q722K	Neutral	0.32
NPC1	O15118-1.2	Q722L	Neutral	0.489
NPC1	O15118-1.2	Q722M	Neutral	0.341
NPC1	O15118-1.2	Q722N	Neutral	0.437
NPC1	O15118-1.2	Q722P	Neutral	0.496
NPC1	O15118-1.2	Q722R	Neutral	0.337
NPC1	O15118-1.2	Q722S	Neutral	0.488
NPC1	O15118-1.2	Q722T	Pathogenic	0.529
NPC1	O15118-1.2	Q722V	Pathogenic	0.528
NPC1	O15118-1.2	Q722W	Pathogenic	0.502
NPC1	O15118-1.2	Q722Y	Neutral	0.48
NPC1	O15118-1.2	Q723A	Pathogenic	0.801
NPC1	O15118-1.2	Q723C	Pathogenic	0.862
NPC1	O15118-1.2	Q723D	Pathogenic	0.702
NPC1	O15118-1.2	Q723E	Pathogenic	0.505
NPC1	O15118-1.2	Q723F	Pathogenic	0.82
NPC1	O15118-1.2	Q723G	Pathogenic	0.881
NPC1	O15118-1.2	Q723H	Pathogenic	0.692
NPC1	O15118-1.2	Q723I	Pathogenic	0.809
NPC1	O15118-1.2	Q723K	Pathogenic	0.595
NPC1	O15118-1.2	Q723L	Pathogenic	0.749
NPC1	O15118-1.2	Q723M	Pathogenic	0.617
NPC1	O15118-1.2	Q723N	Pathogenic	0.707
NPC1	O15118-1.2	Q723P	Pathogenic	0.754
NPC1	O15118-1.2	Q723R	Pathogenic	0.613
NPC1	O15118-1.2	Q723S	Pathogenic	0.748
NPC1	O15118-1.2	Q723T	Pathogenic	0.778
NPC1	O15118-1.2	Q723V	Pathogenic	0.777
NPC1	O15118-1.2	Q723W	Pathogenic	0.759
NPC1	O15118-1.2	Q723Y	Pathogenic	0.742
NPC1	O15118-1.2	L724A	Pathogenic	0.596
NPC1	O15118-1.2	L724C	Pathogenic	0.622
NPC1	O15118-1.2	L724D	Pathogenic	0.739
NPC1	O15118-1.2	L724E	Pathogenic	0.644
NPC1	O15118-1.2	L724F	Pathogenic	0.54
NPC1	O15118-1.2	L724G	Pathogenic	0.826
NPC1	O15118-1.2	L724H	Pathogenic	0.689
NPC1	O15118-1.2	L724I	Neutral	0.335
NPC1	O15118-1.2	L724K	Pathogenic	0.516
NPC1	O15118-1.2	L724M	Neutral	0.309
NPC1	O15118-1.2	L724N	Pathogenic	0.664
NPC1	O15118-1.2	L724P	Pathogenic	0.761
NPC1	O15118-1.2	L724Q	Pathogenic	0.578
NPC1	O15118-1.2	L724R	Pathogenic	0.535
NPC1	O15118-1.2	L724S	Pathogenic	0.651
NPC1	O15118-1.2	L724T	Pathogenic	0.554
NPC1	O15118-1.2	L724V	Neutral	0.423
NPC1	O15118-1.2	L724W	Pathogenic	0.72
NPC1	O15118-1.2	L724Y	Pathogenic	0.59
NPC1	O15118-1.2	G725A	Pathogenic	0.868
NPC1	O15118-1.2	G725C	Pathogenic	0.949
NPC1	O15118-1.2	G725D	Pathogenic	0.905
NPC1	O15118-1.2	G725E	Pathogenic	0.943
NPC1	O15118-1.2	G725F	Pathogenic	0.951
NPC1	O15118-1.2	G725H	Pathogenic	0.953
NPC1	O15118-1.2	G725I	Pathogenic	0.963
NPC1	O15118-1.2	G725K	Pathogenic	0.945
NPC1	O15118-1.2	G725L	Pathogenic	0.965
NPC1	O15118-1.2	G725M	Pathogenic	0.956
NPC1	O15118-1.2	G725N	Pathogenic	0.876
NPC1	O15118-1.2	G725P	Pathogenic	0.934
NPC1	O15118-1.2	G725Q	Pathogenic	0.951
NPC1	O15118-1.2	G725R	Pathogenic	0.948
NPC1	O15118-1.2	G725S	Pathogenic	0.882
NPC1	O15118-1.2	G725T	Pathogenic	0.944
NPC1	O15118-1.2	G725V	Pathogenic	0.951
NPC1	O15118-1.2	G725W	Pathogenic	0.93
NPC1	O15118-1.2	G725Y	Pathogenic	0.963
NPC1	O15118-1.2	R726A	Pathogenic	0.953
NPC1	O15118-1.2	R726C	Pathogenic	0.969
NPC1	O15118-1.2	R726D	Pathogenic	0.974
NPC1	O15118-1.2	R726E	Pathogenic	0.936
NPC1	O15118-1.2	R726F	Pathogenic	0.947
NPC1	O15118-1.2	R726G	Pathogenic	0.974
NPC1	O15118-1.2	R726H	Pathogenic	0.915
NPC1	O15118-1.2	R726I	Pathogenic	0.95
NPC1	O15118-1.2	R726K	Pathogenic	0.866
NPC1	O15118-1.2	R726L	Pathogenic	0.93
NPC1	O15118-1.2	R726M	Pathogenic	0.913
NPC1	O15118-1.2	R726N	Pathogenic	0.94
NPC1	O15118-1.2	R726P	Pathogenic	0.958
NPC1	O15118-1.2	R726Q	Pathogenic	0.893
NPC1	O15118-1.2	R726S	Pathogenic	0.956
NPC1	O15118-1.2	R726T	Pathogenic	0.946
NPC1	O15118-1.2	R726V	Pathogenic	0.963
NPC1	O15118-1.2	R726W	Pathogenic	0.939
NPC1	O15118-1.2	R726Y	Pathogenic	0.939
NPC1	O15118-1.2	V727A	Pathogenic	0.565
NPC1	O15118-1.2	V727C	Pathogenic	0.681
NPC1	O15118-1.2	V727D	Pathogenic	0.714
NPC1	O15118-1.2	V727E	Pathogenic	0.626
NPC1	O15118-1.2	V727F	Pathogenic	0.671
NPC1	O15118-1.2	V727G	Pathogenic	0.807
NPC1	O15118-1.2	V727H	Pathogenic	0.77
NPC1	O15118-1.2	V727I	Neutral	0.289
NPC1	O15118-1.2	V727K	Pathogenic	0.635
NPC1	O15118-1.2	V727L	Neutral	0.476
NPC1	O15118-1.2	V727M	Pathogenic	0.515
NPC1	O15118-1.2	V727N	Pathogenic	0.72
NPC1	O15118-1.2	V727P	Pathogenic	0.737
NPC1	O15118-1.2	V727Q	Pathogenic	0.664
NPC1	O15118-1.2	V727R	Pathogenic	0.734
NPC1	O15118-1.2	V727S	Pathogenic	0.708
NPC1	O15118-1.2	V727T	Pathogenic	0.522
NPC1	O15118-1.2	V727W	Pathogenic	0.818
NPC1	O15118-1.2	V727Y	Pathogenic	0.701
NPC1	O15118-1.2	L728A	Pathogenic	0.851
NPC1	O15118-1.2	L728C	Pathogenic	0.864
NPC1	O15118-1.2	L728D	Pathogenic	0.916
NPC1	O15118-1.2	L728E	Pathogenic	0.875
NPC1	O15118-1.2	L728F	Pathogenic	0.819
NPC1	O15118-1.2	L728G	Pathogenic	0.948
NPC1	O15118-1.2	L728H	Pathogenic	0.895
NPC1	O15118-1.2	L728I	Pathogenic	0.661
NPC1	O15118-1.2	L728K	Pathogenic	0.805
NPC1	O15118-1.2	L728M	Pathogenic	0.633
NPC1	O15118-1.2	L728N	Pathogenic	0.884
NPC1	O15118-1.2	L728P	Pathogenic	0.925
NPC1	O15118-1.2	L728Q	Pathogenic	0.841
NPC1	O15118-1.2	L728R	Pathogenic	0.816
NPC1	O15118-1.2	L728S	Pathogenic	0.878
NPC1	O15118-1.2	L728T	Pathogenic	0.827
NPC1	O15118-1.2	L728V	Pathogenic	0.739
NPC1	O15118-1.2	L728W	Pathogenic	0.909
NPC1	O15118-1.2	L728Y	Pathogenic	0.848
NPC1	O15118-1.2	G729A	Pathogenic	0.902
NPC1	O15118-1.2	G729C	Pathogenic	0.963
NPC1	O15118-1.2	G729D	Pathogenic	0.931
NPC1	O15118-1.2	G729E	Pathogenic	0.959
NPC1	O15118-1.2	G729F	Pathogenic	0.964
NPC1	O15118-1.2	G729H	Pathogenic	0.967
NPC1	O15118-1.2	G729I	Pathogenic	0.974
NPC1	O15118-1.2	G729K	Pathogenic	0.96
NPC1	O15118-1.2	G729L	Pathogenic	0.975
NPC1	O15118-1.2	G729M	Pathogenic	0.968
NPC1	O15118-1.2	G729N	Pathogenic	0.909
NPC1	O15118-1.2	G729P	Pathogenic	0.953
NPC1	O15118-1.2	G729Q	Pathogenic	0.965
NPC1	O15118-1.2	G729R	Pathogenic	0.963
NPC1	O15118-1.2	G729S	Pathogenic	0.913
NPC1	O15118-1.2	G729T	Pathogenic	0.96
NPC1	O15118-1.2	G729V	Pathogenic	0.965
NPC1	O15118-1.2	G729W	Pathogenic	0.949
NPC1	O15118-1.2	G729Y	Pathogenic	0.974
NPC1	O15118-1.2	E730A	Neutral	0.368
NPC1	O15118-1.2	E730C	Pathogenic	0.569
NPC1	O15118-1.2	E730D	Neutral	0.172
NPC1	O15118-1.2	E730F	Neutral	0.411
NPC1	O15118-1.2	E730G	Pathogenic	0.516
NPC1	O15118-1.2	E730H	Neutral	0.256
NPC1	O15118-1.2	E730I	Neutral	0.394
NPC1	O15118-1.2	E730K	Neutral	0.229
NPC1	O15118-1.2	E730L	Neutral	0.402
NPC1	O15118-1.2	E730M	Neutral	0.349
NPC1	O15118-1.2	E730N	Neutral	0.31
NPC1	O15118-1.2	E730P	Neutral	0.307
NPC1	O15118-1.2	E730Q	Neutral	0.148
NPC1	O15118-1.2	E730R	Neutral	0.32
NPC1	O15118-1.2	E730S	Neutral	0.3
NPC1	O15118-1.2	E730T	Neutral	0.336
NPC1	O15118-1.2	E730V	Neutral	0.335
NPC1	O15118-1.2	E730W	Neutral	0.415
NPC1	O15118-1.2	E730Y	Neutral	0.394
NPC1	O15118-1.2	V731A	Pathogenic	0.868
NPC1	O15118-1.2	V731C	Pathogenic	0.915
NPC1	O15118-1.2	V731D	Pathogenic	0.927
NPC1	O15118-1.2	V731E	Pathogenic	0.894
NPC1	O15118-1.2	V731F	Pathogenic	0.912
NPC1	O15118-1.2	V731G	Pathogenic	0.955
NPC1	O15118-1.2	V731H	Pathogenic	0.944
NPC1	O15118-1.2	V731I	Pathogenic	0.672
NPC1	O15118-1.2	V731K	Pathogenic	0.898
NPC1	O15118-1.2	V731L	Pathogenic	0.821
NPC1	O15118-1.2	V731M	Pathogenic	0.843
NPC1	O15118-1.2	V731N	Pathogenic	0.928
NPC1	O15118-1.2	V731P	Pathogenic	0.934
NPC1	O15118-1.2	V731Q	Pathogenic	0.909
NPC1	O15118-1.2	V731R	Pathogenic	0.933
NPC1	O15118-1.2	V731S	Pathogenic	0.924
NPC1	O15118-1.2	V731T	Pathogenic	0.847
NPC1	O15118-1.2	V731W	Pathogenic	0.958
NPC1	O15118-1.2	V731Y	Pathogenic	0.922
NPC1	O15118-1.2	A732C	Pathogenic	0.736
NPC1	O15118-1.2	A732D	Pathogenic	0.845
NPC1	O15118-1.2	A732E	Pathogenic	0.812
NPC1	O15118-1.2	A732F	Pathogenic	0.861
NPC1	O15118-1.2	A732G	Pathogenic	0.759
NPC1	O15118-1.2	A732H	Pathogenic	0.896
NPC1	O15118-1.2	A732I	Pathogenic	0.797
NPC1	O15118-1.2	A732K	Pathogenic	0.818
NPC1	O15118-1.2	A732L	Pathogenic	0.803
NPC1	O15118-1.2	A732M	Pathogenic	0.826
NPC1	O15118-1.2	A732N	Pathogenic	0.856
NPC1	O15118-1.2	A732P	Pathogenic	0.821
NPC1	O15118-1.2	A732Q	Pathogenic	0.836
NPC1	O15118-1.2	A732R	Pathogenic	0.828
NPC1	O15118-1.2	A732S	Pathogenic	0.662
NPC1	O15118-1.2	A732T	Pathogenic	0.782
NPC1	O15118-1.2	A732V	Pathogenic	0.743
NPC1	O15118-1.2	A732W	Pathogenic	0.903
NPC1	O15118-1.2	A732Y	Pathogenic	0.894
NPC1	O15118-1.2	P733A	Pathogenic	0.956
NPC1	O15118-1.2	P733C	Pathogenic	0.978
NPC1	O15118-1.2	P733D	Pathogenic	0.93
NPC1	O15118-1.2	P733E	Pathogenic	0.939
NPC1	O15118-1.2	P733F	Pathogenic	0.984
NPC1	O15118-1.2	P733G	Pathogenic	0.97
NPC1	O15118-1.2	P733H	Pathogenic	0.969
NPC1	O15118-1.2	P733I	Pathogenic	0.976
NPC1	O15118-1.2	P733K	Pathogenic	0.941
NPC1	O15118-1.2	P733L	Pathogenic	0.976
NPC1	O15118-1.2	P733M	Pathogenic	0.97
NPC1	O15118-1.2	P733N	Pathogenic	0.955
NPC1	O15118-1.2	P733Q	Pathogenic	0.948
NPC1	O15118-1.2	P733R	Pathogenic	0.962
NPC1	O15118-1.2	P733S	Pathogenic	0.949
NPC1	O15118-1.2	P733T	Pathogenic	0.949
NPC1	O15118-1.2	P733V	Pathogenic	0.967
NPC1	O15118-1.2	P733W	Pathogenic	0.985
NPC1	O15118-1.2	P733Y	Pathogenic	0.983
NPC1	O15118-1.2	S734A	Pathogenic	0.838
NPC1	O15118-1.2	S734C	Pathogenic	0.903
NPC1	O15118-1.2	S734D	Pathogenic	0.878
NPC1	O15118-1.2	S734E	Pathogenic	0.893
NPC1	O15118-1.2	S734F	Pathogenic	0.934
NPC1	O15118-1.2	S734G	Pathogenic	0.904
NPC1	O15118-1.2	S734H	Pathogenic	0.938
NPC1	O15118-1.2	S734I	Pathogenic	0.929
NPC1	O15118-1.2	S734K	Pathogenic	0.897
NPC1	O15118-1.2	S734L	Pathogenic	0.932
NPC1	O15118-1.2	S734M	Pathogenic	0.915
NPC1	O15118-1.2	S734N	Pathogenic	0.842
NPC1	O15118-1.2	S734P	Pathogenic	0.913
NPC1	O15118-1.2	S734Q	Pathogenic	0.909
NPC1	O15118-1.2	S734R	Pathogenic	0.933
NPC1	O15118-1.2	S734T	Pathogenic	0.852
NPC1	O15118-1.2	S734V	Pathogenic	0.934
NPC1	O15118-1.2	S734W	Pathogenic	0.955
NPC1	O15118-1.2	S734Y	Pathogenic	0.951
NPC1	O15118-1.2	M735A	Pathogenic	0.764
NPC1	O15118-1.2	M735C	Pathogenic	0.783
NPC1	O15118-1.2	M735D	Pathogenic	0.809
NPC1	O15118-1.2	M735E	Pathogenic	0.73
NPC1	O15118-1.2	M735F	Pathogenic	0.653
NPC1	O15118-1.2	M735G	Pathogenic	0.877
NPC1	O15118-1.2	M735H	Pathogenic	0.768
NPC1	O15118-1.2	M735I	Pathogenic	0.544
NPC1	O15118-1.2	M735K	Pathogenic	0.615
NPC1	O15118-1.2	M735L	Neutral	0.456
NPC1	O15118-1.2	M735N	Pathogenic	0.747
NPC1	O15118-1.2	M735P	Pathogenic	0.826
NPC1	O15118-1.2	M735Q	Pathogenic	0.582
NPC1	O15118-1.2	M735R	Pathogenic	0.632
NPC1	O15118-1.2	M735S	Pathogenic	0.736
NPC1	O15118-1.2	M735T	Pathogenic	0.732
NPC1	O15118-1.2	M735V	Pathogenic	0.617
NPC1	O15118-1.2	M735W	Pathogenic	0.738
NPC1	O15118-1.2	M735Y	Pathogenic	0.76
NPC1	O15118-1.2	F736A	Pathogenic	0.563
NPC1	O15118-1.2	F736C	Pathogenic	0.59
NPC1	O15118-1.2	F736D	Pathogenic	0.534
NPC1	O15118-1.2	F736E	Pathogenic	0.518
NPC1	O15118-1.2	F736G	Pathogenic	0.658
NPC1	O15118-1.2	F736H	Neutral	0.378
NPC1	O15118-1.2	F736I	Neutral	0.408
NPC1	O15118-1.2	F736K	Neutral	0.45
NPC1	O15118-1.2	F736L	Neutral	0.402
NPC1	O15118-1.2	F736M	Neutral	0.365
NPC1	O15118-1.2	F736N	Pathogenic	0.541
NPC1	O15118-1.2	F736P	Pathogenic	0.736
NPC1	O15118-1.2	F736Q	Pathogenic	0.545
NPC1	O15118-1.2	F736R	Neutral	0.468
NPC1	O15118-1.2	F736S	Pathogenic	0.526
NPC1	O15118-1.2	F736T	Pathogenic	0.52
NPC1	O15118-1.2	F736V	Neutral	0.485
NPC1	O15118-1.2	F736W	Neutral	0.309
NPC1	O15118-1.2	F736Y	Neutral	0.138
NPC1	O15118-1.2	L737A	Pathogenic	0.713
NPC1	O15118-1.2	L737C	Pathogenic	0.735
NPC1	O15118-1.2	L737D	Pathogenic	0.827
NPC1	O15118-1.2	L737E	Pathogenic	0.753
NPC1	O15118-1.2	L737F	Pathogenic	0.664
NPC1	O15118-1.2	L737G	Pathogenic	0.889
NPC1	O15118-1.2	L737H	Pathogenic	0.788
NPC1	O15118-1.2	L737I	Neutral	0.459
NPC1	O15118-1.2	L737K	Pathogenic	0.643
NPC1	O15118-1.2	L737M	Neutral	0.429
NPC1	O15118-1.2	L737N	Pathogenic	0.769
NPC1	O15118-1.2	L737P	Pathogenic	0.843
NPC1	O15118-1.2	L737Q	Pathogenic	0.698
NPC1	O15118-1.2	L737R	Pathogenic	0.659
NPC1	O15118-1.2	L737S	Pathogenic	0.759
NPC1	O15118-1.2	L737T	Pathogenic	0.676
NPC1	O15118-1.2	L737V	Pathogenic	0.553
NPC1	O15118-1.2	L737W	Pathogenic	0.813
NPC1	O15118-1.2	L737Y	Pathogenic	0.708
NPC1	O15118-1.2	S738A	Neutral	0.216
NPC1	O15118-1.2	S738C	Neutral	0.332
NPC1	O15118-1.2	S738D	Neutral	0.277
NPC1	O15118-1.2	S738E	Neutral	0.309
NPC1	O15118-1.2	S738F	Neutral	0.43
NPC1	O15118-1.2	S738G	Neutral	0.335
NPC1	O15118-1.2	S738H	Neutral	0.445
NPC1	O15118-1.2	S738I	Neutral	0.412
NPC1	O15118-1.2	S738K	Neutral	0.318
NPC1	O15118-1.2	S738L	Neutral	0.421
NPC1	O15118-1.2	S738M	Neutral	0.366
NPC1	O15118-1.2	S738N	Neutral	0.221
NPC1	O15118-1.2	S738P	Neutral	0.358
NPC1	O15118-1.2	S738Q	Neutral	0.346
NPC1	O15118-1.2	S738R	Neutral	0.424
NPC1	O15118-1.2	S738T	Neutral	0.234
NPC1	O15118-1.2	S738V	Neutral	0.432
NPC1	O15118-1.2	S738W	Pathogenic	0.53
NPC1	O15118-1.2	S738Y	Pathogenic	0.507
NPC1	O15118-1.2	S739A	Pathogenic	0.612
NPC1	O15118-1.2	S739C	Pathogenic	0.74
NPC1	O15118-1.2	S739D	Pathogenic	0.687
NPC1	O15118-1.2	S739E	Pathogenic	0.719
NPC1	O15118-1.2	S739F	Pathogenic	0.811
NPC1	O15118-1.2	S739G	Pathogenic	0.742
NPC1	O15118-1.2	S739H	Pathogenic	0.821
NPC1	O15118-1.2	S739I	Pathogenic	0.8
NPC1	O15118-1.2	S739K	Pathogenic	0.727
NPC1	O15118-1.2	S739L	Pathogenic	0.806
NPC1	O15118-1.2	S739M	Pathogenic	0.767
NPC1	O15118-1.2	S739N	Pathogenic	0.619
NPC1	O15118-1.2	S739P	Pathogenic	0.761
NPC1	O15118-1.2	S739Q	Pathogenic	0.752
NPC1	O15118-1.2	S739R	Pathogenic	0.808
NPC1	O15118-1.2	S739T	Pathogenic	0.636
NPC1	O15118-1.2	S739V	Pathogenic	0.813
NPC1	O15118-1.2	S739W	Pathogenic	0.865
NPC1	O15118-1.2	S739Y	Pathogenic	0.855
NPC1	O15118-1.2	F740A	Neutral	0.345
NPC1	O15118-1.2	F740C	Neutral	0.37
NPC1	O15118-1.2	F740D	Neutral	0.319
NPC1	O15118-1.2	F740E	Neutral	0.305
NPC1	O15118-1.2	F740G	Neutral	0.439
NPC1	O15118-1.2	F740H	Neutral	0.199
NPC1	O15118-1.2	F740I	Neutral	0.219
NPC1	O15118-1.2	F740K	Neutral	0.25
NPC1	O15118-1.2	F740L	Neutral	0.215
NPC1	O15118-1.2	F740M	Neutral	0.19
NPC1	O15118-1.2	F740N	Neutral	0.324
NPC1	O15118-1.2	F740P	Pathogenic	0.532
NPC1	O15118-1.2	F740Q	Neutral	0.328
NPC1	O15118-1.2	F740R	Neutral	0.264
NPC1	O15118-1.2	F740S	Neutral	0.312
NPC1	O15118-1.2	F740T	Neutral	0.307
NPC1	O15118-1.2	F740V	Neutral	0.278
NPC1	O15118-1.2	F740W	Neutral	0.154
NPC1	O15118-1.2	F740Y	Neutral	0.061
NPC1	O15118-1.2	S741A	Neutral	0.48
NPC1	O15118-1.2	S741C	Pathogenic	0.625
NPC1	O15118-1.2	S741D	Pathogenic	0.562
NPC1	O15118-1.2	S741E	Pathogenic	0.599
NPC1	O15118-1.2	S741F	Pathogenic	0.716
NPC1	O15118-1.2	S741G	Pathogenic	0.628
NPC1	O15118-1.2	S741H	Pathogenic	0.728
NPC1	O15118-1.2	S741I	Pathogenic	0.701
NPC1	O15118-1.2	S741K	Pathogenic	0.609
NPC1	O15118-1.2	S741L	Pathogenic	0.708
NPC1	O15118-1.2	S741M	Pathogenic	0.659
NPC1	O15118-1.2	S741N	Neutral	0.488
NPC1	O15118-1.2	S741P	Pathogenic	0.651
NPC1	O15118-1.2	S741Q	Pathogenic	0.639
NPC1	O15118-1.2	S741R	Pathogenic	0.712
NPC1	O15118-1.2	S741T	Pathogenic	0.506
NPC1	O15118-1.2	S741V	Pathogenic	0.718
NPC1	O15118-1.2	S741W	Pathogenic	0.79
NPC1	O15118-1.2	S741Y	Pathogenic	0.775
NPC1	O15118-1.2	E742A	Pathogenic	0.844
NPC1	O15118-1.2	E742C	Pathogenic	0.925
NPC1	O15118-1.2	E742D	Pathogenic	0.659
NPC1	O15118-1.2	E742F	Pathogenic	0.867
NPC1	O15118-1.2	E742G	Pathogenic	0.908
NPC1	O15118-1.2	E742H	Pathogenic	0.762
NPC1	O15118-1.2	E742I	Pathogenic	0.858
NPC1	O15118-1.2	E742K	Pathogenic	0.735
NPC1	O15118-1.2	E742L	Pathogenic	0.863
NPC1	O15118-1.2	E742M	Pathogenic	0.833
NPC1	O15118-1.2	E742N	Pathogenic	0.807
NPC1	O15118-1.2	E742P	Pathogenic	0.805
NPC1	O15118-1.2	E742Q	Pathogenic	0.619
NPC1	O15118-1.2	E742R	Pathogenic	0.815
NPC1	O15118-1.2	E742S	Pathogenic	0.8
NPC1	O15118-1.2	E742T	Pathogenic	0.825
NPC1	O15118-1.2	E742V	Pathogenic	0.824
NPC1	O15118-1.2	E742W	Pathogenic	0.869
NPC1	O15118-1.2	E742Y	Pathogenic	0.858
NPC1	O15118-1.2	T743A	Neutral	0.349
NPC1	O15118-1.2	T743C	Neutral	0.36
NPC1	O15118-1.2	T743D	Neutral	0.33
NPC1	O15118-1.2	T743E	Neutral	0.359
NPC1	O15118-1.2	T743F	Neutral	0.438
NPC1	O15118-1.2	T743G	Pathogenic	0.549
NPC1	O15118-1.2	T743H	Pathogenic	0.529
NPC1	O15118-1.2	T743I	Neutral	0.331
NPC1	O15118-1.2	T743K	Neutral	0.369
NPC1	O15118-1.2	T743L	Neutral	0.338
NPC1	O15118-1.2	T743M	Neutral	0.374
NPC1	O15118-1.2	T743N	Neutral	0.263
NPC1	O15118-1.2	T743P	Neutral	0.374
NPC1	O15118-1.2	T743Q	Neutral	0.399
NPC1	O15118-1.2	T743R	Neutral	0.386
NPC1	O15118-1.2	T743S	Neutral	0.245
NPC1	O15118-1.2	T743V	Neutral	0.267
NPC1	O15118-1.2	T743W	Neutral	0.442
NPC1	O15118-1.2	T743Y	Pathogenic	0.516
NPC1	O15118-1.2	V744A	Neutral	0.153
NPC1	O15118-1.2	V744C	Neutral	0.229
NPC1	O15118-1.2	V744D	Neutral	0.258
NPC1	O15118-1.2	V744E	Neutral	0.189
NPC1	O15118-1.2	V744F	Neutral	0.221
NPC1	O15118-1.2	V744G	Neutral	0.368
NPC1	O15118-1.2	V744H	Neutral	0.318
NPC1	O15118-1.2	V744I	Neutral	0.053
NPC1	O15118-1.2	V744K	Neutral	0.195
NPC1	O15118-1.2	V744L	Neutral	0.112
NPC1	O15118-1.2	V744M	Neutral	0.128
NPC1	O15118-1.2	V744N	Neutral	0.263
NPC1	O15118-1.2	V744P	Neutral	0.28
NPC1	O15118-1.2	V744Q	Neutral	0.216
NPC1	O15118-1.2	V744R	Neutral	0.277
NPC1	O15118-1.2	V744S	Neutral	0.252
NPC1	O15118-1.2	V744T	Neutral	0.132
NPC1	O15118-1.2	V744W	Neutral	0.384
NPC1	O15118-1.2	V744Y	Neutral	0.246
NPC1	O15118-1.2	A745C	Neutral	0.366
NPC1	O15118-1.2	A745D	Pathogenic	0.53
NPC1	O15118-1.2	A745E	Neutral	0.472
NPC1	O15118-1.2	A745F	Pathogenic	0.563
NPC1	O15118-1.2	A745G	Neutral	0.395
NPC1	O15118-1.2	A745H	Pathogenic	0.642
NPC1	O15118-1.2	A745I	Neutral	0.449
NPC1	O15118-1.2	A745K	Neutral	0.482
NPC1	O15118-1.2	A745L	Neutral	0.457
NPC1	O15118-1.2	A745M	Neutral	0.496
NPC1	O15118-1.2	A745N	Pathogenic	0.552
NPC1	O15118-1.2	A745P	Neutral	0.488
NPC1	O15118-1.2	A745Q	Pathogenic	0.514
NPC1	O15118-1.2	A745R	Pathogenic	0.5
NPC1	O15118-1.2	A745S	Neutral	0.289
NPC1	O15118-1.2	A745T	Neutral	0.426
NPC1	O15118-1.2	A745V	Neutral	0.375
NPC1	O15118-1.2	A745W	Pathogenic	0.658
NPC1	O15118-1.2	A745Y	Pathogenic	0.637
NPC1	O15118-1.2	F746A	Pathogenic	0.866
NPC1	O15118-1.2	F746C	Pathogenic	0.878
NPC1	O15118-1.2	F746D	Pathogenic	0.851
NPC1	O15118-1.2	F746E	Pathogenic	0.843
NPC1	O15118-1.2	F746G	Pathogenic	0.906
NPC1	O15118-1.2	F746H	Pathogenic	0.752
NPC1	O15118-1.2	F746I	Pathogenic	0.774
NPC1	O15118-1.2	F746K	Pathogenic	0.803
NPC1	O15118-1.2	F746L	Pathogenic	0.77
NPC1	O15118-1.2	F746M	Pathogenic	0.741
NPC1	O15118-1.2	F746N	Pathogenic	0.855
NPC1	O15118-1.2	F746P	Pathogenic	0.933
NPC1	O15118-1.2	F746Q	Pathogenic	0.857
NPC1	O15118-1.2	F746R	Pathogenic	0.815
NPC1	O15118-1.2	F746S	Pathogenic	0.847
NPC1	O15118-1.2	F746T	Pathogenic	0.844
NPC1	O15118-1.2	F746V	Pathogenic	0.825
NPC1	O15118-1.2	F746W	Pathogenic	0.69
NPC1	O15118-1.2	F746Y	Neutral	0.444
NPC1	O15118-1.2	F747A	Pathogenic	0.763
NPC1	O15118-1.2	F747C	Pathogenic	0.782
NPC1	O15118-1.2	F747D	Pathogenic	0.741
NPC1	O15118-1.2	F747E	Pathogenic	0.728
NPC1	O15118-1.2	F747G	Pathogenic	0.827
NPC1	O15118-1.2	F747H	Pathogenic	0.602
NPC1	O15118-1.2	F747I	Pathogenic	0.632
NPC1	O15118-1.2	F747K	Pathogenic	0.671
NPC1	O15118-1.2	F747L	Pathogenic	0.626
NPC1	O15118-1.2	F747M	Pathogenic	0.589
NPC1	O15118-1.2	F747N	Pathogenic	0.746
NPC1	O15118-1.2	F747P	Pathogenic	0.874
NPC1	O15118-1.2	F747Q	Pathogenic	0.749
NPC1	O15118-1.2	F747R	Pathogenic	0.687
NPC1	O15118-1.2	F747S	Pathogenic	0.734
NPC1	O15118-1.2	F747T	Pathogenic	0.73
NPC1	O15118-1.2	F747V	Pathogenic	0.701
NPC1	O15118-1.2	F747W	Pathogenic	0.527
NPC1	O15118-1.2	F747Y	Neutral	0.285
NPC1	O15118-1.2	L748A	Pathogenic	0.692
NPC1	O15118-1.2	L748C	Pathogenic	0.714
NPC1	O15118-1.2	L748D	Pathogenic	0.812
NPC1	O15118-1.2	L748E	Pathogenic	0.733
NPC1	O15118-1.2	L748F	Pathogenic	0.64
NPC1	O15118-1.2	L748G	Pathogenic	0.878
NPC1	O15118-1.2	L748H	Pathogenic	0.771
NPC1	O15118-1.2	L748I	Neutral	0.434
NPC1	O15118-1.2	L748K	Pathogenic	0.619
NPC1	O15118-1.2	L748M	Neutral	0.404
NPC1	O15118-1.2	L748N	Pathogenic	0.751
NPC1	O15118-1.2	L748P	Pathogenic	0.829
NPC1	O15118-1.2	L748Q	Pathogenic	0.676
NPC1	O15118-1.2	L748R	Pathogenic	0.636
NPC1	O15118-1.2	L748S	Pathogenic	0.739
NPC1	O15118-1.2	L748T	Pathogenic	0.653
NPC1	O15118-1.2	L748V	Pathogenic	0.527
NPC1	O15118-1.2	L748W	Pathogenic	0.797
NPC1	O15118-1.2	L748Y	Pathogenic	0.686
NPC1	O15118-1.2	G749A	Pathogenic	0.811
NPC1	O15118-1.2	G749C	Pathogenic	0.925
NPC1	O15118-1.2	G749D	Pathogenic	0.862
NPC1	O15118-1.2	G749E	Pathogenic	0.915
NPC1	O15118-1.2	G749F	Pathogenic	0.927
NPC1	O15118-1.2	G749H	Pathogenic	0.931
NPC1	O15118-1.2	G749I	Pathogenic	0.945
NPC1	O15118-1.2	G749K	Pathogenic	0.918
NPC1	O15118-1.2	G749L	Pathogenic	0.947
NPC1	O15118-1.2	G749M	Pathogenic	0.934
NPC1	O15118-1.2	G749N	Pathogenic	0.823
NPC1	O15118-1.2	G749P	Pathogenic	0.903
NPC1	O15118-1.2	G749Q	Pathogenic	0.927
NPC1	O15118-1.2	G749R	Pathogenic	0.923
NPC1	O15118-1.2	G749S	Pathogenic	0.83
NPC1	O15118-1.2	G749T	Pathogenic	0.917
NPC1	O15118-1.2	G749V	Pathogenic	0.927
NPC1	O15118-1.2	G749W	Pathogenic	0.897
NPC1	O15118-1.2	G749Y	Pathogenic	0.945
NPC1	O15118-1.2	A750C	Neutral	0.223
NPC1	O15118-1.2	A750D	Neutral	0.359
NPC1	O15118-1.2	A750E	Neutral	0.307
NPC1	O15118-1.2	A750F	Neutral	0.389
NPC1	O15118-1.2	A750G	Neutral	0.245
NPC1	O15118-1.2	A750H	Neutral	0.47
NPC1	O15118-1.2	A750I	Neutral	0.288
NPC1	O15118-1.2	A750K	Neutral	0.316
NPC1	O15118-1.2	A750L	Neutral	0.295
NPC1	O15118-1.2	A750M	Neutral	0.328
NPC1	O15118-1.2	A750N	Neutral	0.379
NPC1	O15118-1.2	A750P	Neutral	0.32
NPC1	O15118-1.2	A750Q	Neutral	0.344
NPC1	O15118-1.2	A750R	Neutral	0.332
NPC1	O15118-1.2	A750S	Neutral	0.167
NPC1	O15118-1.2	A750T	Neutral	0.269
NPC1	O15118-1.2	A750V	Neutral	0.229
NPC1	O15118-1.2	A750W	Neutral	0.488
NPC1	O15118-1.2	A750Y	Neutral	0.466
NPC1	O15118-1.2	L751A	Pathogenic	0.696
NPC1	O15118-1.2	L751C	Pathogenic	0.718
NPC1	O15118-1.2	L751D	Pathogenic	0.815
NPC1	O15118-1.2	L751E	Pathogenic	0.737
NPC1	O15118-1.2	L751F	Pathogenic	0.645
NPC1	O15118-1.2	L751G	Pathogenic	0.88
NPC1	O15118-1.2	L751H	Pathogenic	0.774
NPC1	O15118-1.2	L751I	Neutral	0.439
NPC1	O15118-1.2	L751K	Pathogenic	0.623
NPC1	O15118-1.2	L751M	Neutral	0.409
NPC1	O15118-1.2	L751N	Pathogenic	0.754
NPC1	O15118-1.2	L751P	Pathogenic	0.831
NPC1	O15118-1.2	L751Q	Pathogenic	0.68
NPC1	O15118-1.2	L751R	Pathogenic	0.64
NPC1	O15118-1.2	L751S	Pathogenic	0.743
NPC1	O15118-1.2	L751T	Pathogenic	0.657
NPC1	O15118-1.2	L751V	Pathogenic	0.532
NPC1	O15118-1.2	L751W	Pathogenic	0.8
NPC1	O15118-1.2	L751Y	Pathogenic	0.69
NPC1	O15118-1.2	S752A	Pathogenic	0.572
NPC1	O15118-1.2	S752C	Pathogenic	0.707
NPC1	O15118-1.2	S752D	Pathogenic	0.65
NPC1	O15118-1.2	S752E	Pathogenic	0.684
NPC1	O15118-1.2	S752F	Pathogenic	0.785
NPC1	O15118-1.2	S752G	Pathogenic	0.71
NPC1	O15118-1.2	S752H	Pathogenic	0.795
NPC1	O15118-1.2	S752I	Pathogenic	0.773
NPC1	O15118-1.2	S752K	Pathogenic	0.693
NPC1	O15118-1.2	S752L	Pathogenic	0.779
NPC1	O15118-1.2	S752M	Pathogenic	0.737
NPC1	O15118-1.2	S752N	Pathogenic	0.58
NPC1	O15118-1.2	S752P	Pathogenic	0.73
NPC1	O15118-1.2	S752Q	Pathogenic	0.72
NPC1	O15118-1.2	S752R	Pathogenic	0.781
NPC1	O15118-1.2	S752T	Pathogenic	0.597
NPC1	O15118-1.2	S752V	Pathogenic	0.787
NPC1	O15118-1.2	S752W	Pathogenic	0.845
NPC1	O15118-1.2	S752Y	Pathogenic	0.833
NPC1	O15118-1.2	V753A	Neutral	0.043
NPC1	O15118-1.2	V753C	Neutral	0.069
NPC1	O15118-1.2	V753D	Neutral	0.08
NPC1	O15118-1.2	V753E	Neutral	0.055
NPC1	O15118-1.2	V753F	Neutral	0.066
NPC1	O15118-1.2	V753G	Neutral	0.127
NPC1	O15118-1.2	V753H	Neutral	0.104
NPC1	O15118-1.2	V753I	Neutral	0.014
NPC1	O15118-1.2	V753K	Neutral	0.057
NPC1	O15118-1.2	V753L	Neutral	0.03
NPC1	O15118-1.2	V753M	Neutral	0.035
NPC1	O15118-1.2	V753N	Neutral	0.082
NPC1	O15118-1.2	V753P	Neutral	0.089
NPC1	O15118-1.2	V753Q	Neutral	0.064
NPC1	O15118-1.2	V753R	Neutral	0.087
NPC1	O15118-1.2	V753S	Neutral	0.077
NPC1	O15118-1.2	V753T	Neutral	0.036
NPC1	O15118-1.2	V753W	Neutral	0.134
NPC1	O15118-1.2	V753Y	Neutral	0.075
NPC1	O15118-1.2	M754A	Pathogenic	0.888
NPC1	O15118-1.2	M754C	Pathogenic	0.899
NPC1	O15118-1.2	M754D	Pathogenic	0.912
NPC1	O15118-1.2	M754E	Pathogenic	0.869
NPC1	O15118-1.2	M754F	Pathogenic	0.822
NPC1	O15118-1.2	M754G	Pathogenic	0.946
NPC1	O15118-1.2	M754H	Pathogenic	0.89
NPC1	O15118-1.2	M754I	Pathogenic	0.745
NPC1	O15118-1.2	M754K	Pathogenic	0.796
NPC1	O15118-1.2	M754L	Pathogenic	0.673
NPC1	O15118-1.2	M754N	Pathogenic	0.879
NPC1	O15118-1.2	M754P	Pathogenic	0.921
NPC1	O15118-1.2	M754Q	Pathogenic	0.773
NPC1	O15118-1.2	M754R	Pathogenic	0.808
NPC1	O15118-1.2	M754S	Pathogenic	0.872
NPC1	O15118-1.2	M754T	Pathogenic	0.87
NPC1	O15118-1.2	M754V	Pathogenic	0.798
NPC1	O15118-1.2	M754W	Pathogenic	0.873
NPC1	O15118-1.2	M754Y	Pathogenic	0.886
NPC1	O15118-1.2	P755A	Pathogenic	0.863
NPC1	O15118-1.2	P755C	Pathogenic	0.927
NPC1	O15118-1.2	P755D	Pathogenic	0.794
NPC1	O15118-1.2	P755E	Pathogenic	0.818
NPC1	O15118-1.2	P755F	Pathogenic	0.948
NPC1	O15118-1.2	P755G	Pathogenic	0.904
NPC1	O15118-1.2	P755H	Pathogenic	0.9
NPC1	O15118-1.2	P755I	Pathogenic	0.921
NPC1	O15118-1.2	P755K	Pathogenic	0.824
NPC1	O15118-1.2	P755L	Pathogenic	0.923
NPC1	O15118-1.2	P755M	Pathogenic	0.906
NPC1	O15118-1.2	P755N	Pathogenic	0.861
NPC1	O15118-1.2	P755Q	Pathogenic	0.842
NPC1	O15118-1.2	P755R	Pathogenic	0.881
NPC1	O15118-1.2	P755S	Pathogenic	0.844
NPC1	O15118-1.2	P755T	Pathogenic	0.846
NPC1	O15118-1.2	P755V	Pathogenic	0.896
NPC1	O15118-1.2	P755W	Pathogenic	0.949
NPC1	O15118-1.2	P755Y	Pathogenic	0.945
NPC1	O15118-1.2	A756C	Pathogenic	0.929
NPC1	O15118-1.2	A756D	Pathogenic	0.963
NPC1	O15118-1.2	A756E	Pathogenic	0.953
NPC1	O15118-1.2	A756F	Pathogenic	0.967
NPC1	O15118-1.2	A756G	Pathogenic	0.937
NPC1	O15118-1.2	A756H	Pathogenic	0.976
NPC1	O15118-1.2	A756I	Pathogenic	0.949
NPC1	O15118-1.2	A756K	Pathogenic	0.955
NPC1	O15118-1.2	A756L	Pathogenic	0.95
NPC1	O15118-1.2	A756M	Pathogenic	0.957
NPC1	O15118-1.2	A756N	Pathogenic	0.966
NPC1	O15118-1.2	A756P	Pathogenic	0.956
NPC1	O15118-1.2	A756Q	Pathogenic	0.96
NPC1	O15118-1.2	A756R	Pathogenic	0.958
NPC1	O15118-1.2	A756S	Pathogenic	0.902
NPC1	O15118-1.2	A756T	Pathogenic	0.944
NPC1	O15118-1.2	A756V	Pathogenic	0.932
NPC1	O15118-1.2	A756W	Pathogenic	0.978
NPC1	O15118-1.2	A756Y	Pathogenic	0.976
NPC1	O15118-1.2	V757A	Pathogenic	0.921
NPC1	O15118-1.2	V757C	Pathogenic	0.951
NPC1	O15118-1.2	V757D	Pathogenic	0.958
NPC1	O15118-1.2	V757E	Pathogenic	0.938
NPC1	O15118-1.2	V757F	Pathogenic	0.948
NPC1	O15118-1.2	V757G	Pathogenic	0.974
NPC1	O15118-1.2	V757H	Pathogenic	0.968
NPC1	O15118-1.2	V757I	Pathogenic	0.785
NPC1	O15118-1.2	V757K	Pathogenic	0.94
NPC1	O15118-1.2	V757L	Pathogenic	0.891
NPC1	O15118-1.2	V757M	Pathogenic	0.905
NPC1	O15118-1.2	V757N	Pathogenic	0.959
NPC1	O15118-1.2	V757P	Pathogenic	0.962
NPC1	O15118-1.2	V757Q	Pathogenic	0.947
NPC1	O15118-1.2	V757R	Pathogenic	0.961
NPC1	O15118-1.2	V757S	Pathogenic	0.956
NPC1	O15118-1.2	V757T	Pathogenic	0.908
NPC1	O15118-1.2	V757W	Pathogenic	0.976
NPC1	O15118-1.2	V757Y	Pathogenic	0.955
NPC1	O15118-1.2	H758A	Pathogenic	0.858
NPC1	O15118-1.2	H758C	Pathogenic	0.863
NPC1	O15118-1.2	H758D	Pathogenic	0.735
NPC1	O15118-1.2	H758E	Pathogenic	0.639
NPC1	O15118-1.2	H758F	Pathogenic	0.671
NPC1	O15118-1.2	H758G	Pathogenic	0.873
NPC1	O15118-1.2	H758I	Pathogenic	0.804
NPC1	O15118-1.2	H758K	Pathogenic	0.709
NPC1	O15118-1.2	H758L	Pathogenic	0.809
NPC1	O15118-1.2	H758M	Pathogenic	0.771
NPC1	O15118-1.2	H758N	Pathogenic	0.569
NPC1	O15118-1.2	H758P	Pathogenic	0.82
NPC1	O15118-1.2	H758Q	Pathogenic	0.664
NPC1	O15118-1.2	H758R	Pathogenic	0.64
NPC1	O15118-1.2	H758S	Pathogenic	0.798
NPC1	O15118-1.2	H758T	Pathogenic	0.839
NPC1	O15118-1.2	H758V	Pathogenic	0.839
NPC1	O15118-1.2	H758W	Pathogenic	0.753
NPC1	O15118-1.2	H758Y	Neutral	0.466
NPC1	O15118-1.2	T759A	Pathogenic	0.685
NPC1	O15118-1.2	T759C	Pathogenic	0.695
NPC1	O15118-1.2	T759D	Pathogenic	0.667
NPC1	O15118-1.2	T759E	Pathogenic	0.695
NPC1	O15118-1.2	T759F	Pathogenic	0.76
NPC1	O15118-1.2	T759G	Pathogenic	0.831
NPC1	O15118-1.2	T759H	Pathogenic	0.82
NPC1	O15118-1.2	T759I	Pathogenic	0.667
NPC1	O15118-1.2	T759K	Pathogenic	0.703
NPC1	O15118-1.2	T759L	Pathogenic	0.675
NPC1	O15118-1.2	T759M	Pathogenic	0.708
NPC1	O15118-1.2	T759N	Pathogenic	0.591
NPC1	O15118-1.2	T759P	Pathogenic	0.708
NPC1	O15118-1.2	T759Q	Pathogenic	0.729
NPC1	O15118-1.2	T759R	Pathogenic	0.718
NPC1	O15118-1.2	T759S	Pathogenic	0.568
NPC1	O15118-1.2	T759V	Pathogenic	0.596
NPC1	O15118-1.2	T759W	Pathogenic	0.763
NPC1	O15118-1.2	T759Y	Pathogenic	0.812
NPC1	O15118-1.2	F760A	Pathogenic	0.882
NPC1	O15118-1.2	F760C	Pathogenic	0.893
NPC1	O15118-1.2	F760D	Pathogenic	0.869
NPC1	O15118-1.2	F760E	Pathogenic	0.861
NPC1	O15118-1.2	F760G	Pathogenic	0.917
NPC1	O15118-1.2	F760H	Pathogenic	0.779
NPC1	O15118-1.2	F760I	Pathogenic	0.799
NPC1	O15118-1.2	F760K	Pathogenic	0.825
NPC1	O15118-1.2	F760L	Pathogenic	0.795
NPC1	O15118-1.2	F760M	Pathogenic	0.769
NPC1	O15118-1.2	F760N	Pathogenic	0.872
NPC1	O15118-1.2	F760P	Pathogenic	0.942
NPC1	O15118-1.2	F760Q	Pathogenic	0.874
NPC1	O15118-1.2	F760R	Pathogenic	0.836
NPC1	O15118-1.2	F760S	Pathogenic	0.865
NPC1	O15118-1.2	F760T	Pathogenic	0.862
NPC1	O15118-1.2	F760V	Pathogenic	0.845
NPC1	O15118-1.2	F760W	Pathogenic	0.721
NPC1	O15118-1.2	F760Y	Neutral	0.481
NPC1	O15118-1.2	S761A	Neutral	0.362
NPC1	O15118-1.2	S761C	Pathogenic	0.505
NPC1	O15118-1.2	S761D	Neutral	0.441
NPC1	O15118-1.2	S761E	Neutral	0.478
NPC1	O15118-1.2	S761F	Pathogenic	0.607
NPC1	O15118-1.2	S761G	Pathogenic	0.509
NPC1	O15118-1.2	S761H	Pathogenic	0.622
NPC1	O15118-1.2	S761I	Pathogenic	0.59
NPC1	O15118-1.2	S761K	Neutral	0.489
NPC1	O15118-1.2	S761L	Pathogenic	0.598
NPC1	O15118-1.2	S761M	Pathogenic	0.542
NPC1	O15118-1.2	S761N	Neutral	0.369
NPC1	O15118-1.2	S761P	Pathogenic	0.533
NPC1	O15118-1.2	S761Q	Pathogenic	0.521
NPC1	O15118-1.2	S761R	Pathogenic	0.602
NPC1	O15118-1.2	S761T	Neutral	0.385
NPC1	O15118-1.2	S761V	Pathogenic	0.609
NPC1	O15118-1.2	S761W	Pathogenic	0.698
NPC1	O15118-1.2	S761Y	Pathogenic	0.679
NPC1	O15118-1.2	L762A	Pathogenic	0.709
NPC1	O15118-1.2	L762C	Pathogenic	0.731
NPC1	O15118-1.2	L762D	Pathogenic	0.824
NPC1	O15118-1.2	L762E	Pathogenic	0.749
NPC1	O15118-1.2	L762F	Pathogenic	0.659
NPC1	O15118-1.2	L762G	Pathogenic	0.887
NPC1	O15118-1.2	L762H	Pathogenic	0.785
NPC1	O15118-1.2	L762I	Neutral	0.454
NPC1	O15118-1.2	L762K	Pathogenic	0.638
NPC1	O15118-1.2	L762M	Neutral	0.424
NPC1	O15118-1.2	L762N	Pathogenic	0.766
NPC1	O15118-1.2	L762P	Pathogenic	0.84
NPC1	O15118-1.2	L762Q	Pathogenic	0.693
NPC1	O15118-1.2	L762R	Pathogenic	0.655
NPC1	O15118-1.2	L762S	Pathogenic	0.755
NPC1	O15118-1.2	L762T	Pathogenic	0.671
NPC1	O15118-1.2	L762V	Pathogenic	0.547
NPC1	O15118-1.2	L762W	Pathogenic	0.809
NPC1	O15118-1.2	L762Y	Pathogenic	0.703
NPC1	O15118-1.2	F763A	Pathogenic	0.552
NPC1	O15118-1.2	F763C	Pathogenic	0.579
NPC1	O15118-1.2	F763D	Pathogenic	0.523
NPC1	O15118-1.2	F763E	Pathogenic	0.507
NPC1	O15118-1.2	F763G	Pathogenic	0.648
NPC1	O15118-1.2	F763H	Neutral	0.368
NPC1	O15118-1.2	F763I	Neutral	0.397
NPC1	O15118-1.2	F763K	Neutral	0.439
NPC1	O15118-1.2	F763L	Neutral	0.391
NPC1	O15118-1.2	F763M	Neutral	0.355
NPC1	O15118-1.2	F763N	Pathogenic	0.53
NPC1	O15118-1.2	F763P	Pathogenic	0.727
NPC1	O15118-1.2	F763Q	Pathogenic	0.534
NPC1	O15118-1.2	F763R	Neutral	0.457
NPC1	O15118-1.2	F763S	Pathogenic	0.515
NPC1	O15118-1.2	F763T	Pathogenic	0.509
NPC1	O15118-1.2	F763V	Neutral	0.474
NPC1	O15118-1.2	F763W	Neutral	0.299
NPC1	O15118-1.2	F763Y	Neutral	0.133
NPC1	O15118-1.2	A764C	Pathogenic	0.759
NPC1	O15118-1.2	A764D	Pathogenic	0.86
NPC1	O15118-1.2	A764E	Pathogenic	0.829
NPC1	O15118-1.2	A764F	Pathogenic	0.875
NPC1	O15118-1.2	A764G	Pathogenic	0.78
NPC1	O15118-1.2	A764H	Pathogenic	0.907
NPC1	O15118-1.2	A764I	Pathogenic	0.816
NPC1	O15118-1.2	A764K	Pathogenic	0.835
NPC1	O15118-1.2	A764L	Pathogenic	0.821
NPC1	O15118-1.2	A764M	Pathogenic	0.843
NPC1	O15118-1.2	A764N	Pathogenic	0.87
NPC1	O15118-1.2	A764P	Pathogenic	0.838
NPC1	O15118-1.2	A764Q	Pathogenic	0.852
NPC1	O15118-1.2	A764R	Pathogenic	0.845
NPC1	O15118-1.2	A764S	Pathogenic	0.688
NPC1	O15118-1.2	A764T	Pathogenic	0.801
NPC1	O15118-1.2	A764V	Pathogenic	0.765
NPC1	O15118-1.2	A764W	Pathogenic	0.913
NPC1	O15118-1.2	A764Y	Pathogenic	0.905
NPC1	O15118-1.2	G765A	Pathogenic	0.574
NPC1	O15118-1.2	G765C	Pathogenic	0.793
NPC1	O15118-1.2	G765D	Pathogenic	0.662
NPC1	O15118-1.2	G765E	Pathogenic	0.771
NPC1	O15118-1.2	G765F	Pathogenic	0.798
NPC1	O15118-1.2	G765H	Pathogenic	0.808
NPC1	O15118-1.2	G765I	Pathogenic	0.844
NPC1	O15118-1.2	G765K	Pathogenic	0.778
NPC1	O15118-1.2	G765L	Pathogenic	0.848
NPC1	O15118-1.2	G765M	Pathogenic	0.816
NPC1	O15118-1.2	G765N	Pathogenic	0.592
NPC1	O15118-1.2	G765P	Pathogenic	0.745
NPC1	O15118-1.2	G765Q	Pathogenic	0.799
NPC1	O15118-1.2	G765R	Pathogenic	0.79
NPC1	O15118-1.2	G765S	Pathogenic	0.604
NPC1	O15118-1.2	G765T	Pathogenic	0.776
NPC1	O15118-1.2	G765V	Pathogenic	0.799
NPC1	O15118-1.2	G765W	Pathogenic	0.732
NPC1	O15118-1.2	G765Y	Pathogenic	0.843
NPC1	O15118-1.2	L766A	Neutral	0.259
NPC1	O15118-1.2	L766C	Neutral	0.28
NPC1	O15118-1.2	L766D	Neutral	0.402
NPC1	O15118-1.2	L766E	Neutral	0.3
NPC1	O15118-1.2	L766F	Neutral	0.217
NPC1	O15118-1.2	L766G	Pathogenic	0.529
NPC1	O15118-1.2	L766H	Neutral	0.344
NPC1	O15118-1.2	L766I	Neutral	0.107
NPC1	O15118-1.2	L766K	Neutral	0.202
NPC1	O15118-1.2	L766M	Neutral	0.096
NPC1	O15118-1.2	L766N	Neutral	0.319
NPC1	O15118-1.2	L766P	Neutral	0.43
NPC1	O15118-1.2	L766Q	Neutral	0.245
NPC1	O15118-1.2	L766R	Neutral	0.214
NPC1	O15118-1.2	L766S	Neutral	0.306
NPC1	O15118-1.2	L766T	Neutral	0.227
NPC1	O15118-1.2	L766V	Neutral	0.148
NPC1	O15118-1.2	L766W	Neutral	0.379
NPC1	O15118-1.2	L766Y	Neutral	0.254
NPC1	O15118-1.2	A767C	Pathogenic	0.76
NPC1	O15118-1.2	A767D	Pathogenic	0.86
NPC1	O15118-1.2	A767E	Pathogenic	0.83
NPC1	O15118-1.2	A767F	Pathogenic	0.876
NPC1	O15118-1.2	A767G	Pathogenic	0.781
NPC1	O15118-1.2	A767H	Pathogenic	0.907
NPC1	O15118-1.2	A767I	Pathogenic	0.817
NPC1	O15118-1.2	A767K	Pathogenic	0.836
NPC1	O15118-1.2	A767L	Pathogenic	0.822
NPC1	O15118-1.2	A767M	Pathogenic	0.843
NPC1	O15118-1.2	A767N	Pathogenic	0.871
NPC1	O15118-1.2	A767P	Pathogenic	0.839
NPC1	O15118-1.2	A767Q	Pathogenic	0.853
NPC1	O15118-1.2	A767R	Pathogenic	0.846
NPC1	O15118-1.2	A767S	Pathogenic	0.689
NPC1	O15118-1.2	A767T	Pathogenic	0.802
NPC1	O15118-1.2	A767V	Pathogenic	0.766
NPC1	O15118-1.2	A767W	Pathogenic	0.913
NPC1	O15118-1.2	A767Y	Pathogenic	0.906
NPC1	O15118-1.2	V768A	Neutral	0.348
NPC1	O15118-1.2	V768C	Neutral	0.467
NPC1	O15118-1.2	V768D	Pathogenic	0.506
NPC1	O15118-1.2	V768E	Neutral	0.407
NPC1	O15118-1.2	V768F	Neutral	0.455
NPC1	O15118-1.2	V768G	Pathogenic	0.632
NPC1	O15118-1.2	V768H	Pathogenic	0.579
NPC1	O15118-1.2	V768I	Neutral	0.143
NPC1	O15118-1.2	V768K	Neutral	0.417
NPC1	O15118-1.2	V768L	Neutral	0.271
NPC1	O15118-1.2	V768M	Neutral	0.303
NPC1	O15118-1.2	V768N	Pathogenic	0.513
NPC1	O15118-1.2	V768P	Pathogenic	0.535
NPC1	O15118-1.2	V768Q	Neutral	0.448
NPC1	O15118-1.2	V768R	Pathogenic	0.531
NPC1	O15118-1.2	V768S	Neutral	0.498
NPC1	O15118-1.2	V768T	Neutral	0.31
NPC1	O15118-1.2	V768W	Pathogenic	0.648
NPC1	O15118-1.2	V768Y	Neutral	0.491
NPC1	O15118-1.2	F769A	Pathogenic	0.508
NPC1	O15118-1.2	F769C	Pathogenic	0.535
NPC1	O15118-1.2	F769D	Neutral	0.479
NPC1	O15118-1.2	F769E	Neutral	0.463
NPC1	O15118-1.2	F769G	Pathogenic	0.606
NPC1	O15118-1.2	F769H	Neutral	0.327
NPC1	O15118-1.2	F769I	Neutral	0.355
NPC1	O15118-1.2	F769K	Neutral	0.396
NPC1	O15118-1.2	F769L	Neutral	0.35
NPC1	O15118-1.2	F769M	Neutral	0.315
NPC1	O15118-1.2	F769N	Neutral	0.485
NPC1	O15118-1.2	F769P	Pathogenic	0.69
NPC1	O15118-1.2	F769Q	Neutral	0.49
NPC1	O15118-1.2	F769R	Neutral	0.413
NPC1	O15118-1.2	F769S	Neutral	0.471
NPC1	O15118-1.2	F769T	Neutral	0.465
NPC1	O15118-1.2	F769V	Neutral	0.43
NPC1	O15118-1.2	F769W	Neutral	0.263
NPC1	O15118-1.2	F769Y	Neutral	0.114
NPC1	O15118-1.2	I770A	Neutral	0.271
NPC1	O15118-1.2	I770C	Neutral	0.293
NPC1	O15118-1.2	I770D	Neutral	0.327
NPC1	O15118-1.2	I770E	Neutral	0.313
NPC1	O15118-1.2	I770F	Neutral	0.238
NPC1	O15118-1.2	I770G	Pathogenic	0.545
NPC1	O15118-1.2	I770H	Neutral	0.358
NPC1	O15118-1.2	I770K	Neutral	0.283
NPC1	O15118-1.2	I770L	Neutral	0.116
NPC1	O15118-1.2	I770M	Neutral	0.142
NPC1	O15118-1.2	I770N	Neutral	0.333
NPC1	O15118-1.2	I770P	Neutral	0.445
NPC1	O15118-1.2	I770Q	Neutral	0.337
NPC1	O15118-1.2	I770R	Neutral	0.298
NPC1	O15118-1.2	I770S	Neutral	0.32
NPC1	O15118-1.2	I770T	Neutral	0.238
NPC1	O15118-1.2	I770V	Neutral	0.079
NPC1	O15118-1.2	I770W	Pathogenic	0.505
NPC1	O15118-1.2	I770Y	Neutral	0.266
NPC1	O15118-1.2	D771A	Pathogenic	0.826
NPC1	O15118-1.2	D771C	Pathogenic	0.833
NPC1	O15118-1.2	D771E	Pathogenic	0.573
NPC1	O15118-1.2	D771F	Pathogenic	0.829
NPC1	O15118-1.2	D771G	Pathogenic	0.801
NPC1	O15118-1.2	D771H	Pathogenic	0.778
NPC1	O15118-1.2	D771I	Pathogenic	0.818
NPC1	O15118-1.2	D771K	Pathogenic	0.829
NPC1	O15118-1.2	D771L	Pathogenic	0.873
NPC1	O15118-1.2	D771M	Pathogenic	0.845
NPC1	O15118-1.2	D771N	Pathogenic	0.643
NPC1	O15118-1.2	D771P	Pathogenic	0.711
NPC1	O15118-1.2	D771Q	Pathogenic	0.723
NPC1	O15118-1.2	D771R	Pathogenic	0.885
NPC1	O15118-1.2	D771S	Pathogenic	0.704
NPC1	O15118-1.2	D771T	Pathogenic	0.742
NPC1	O15118-1.2	D771V	Pathogenic	0.83
NPC1	O15118-1.2	D771W	Pathogenic	0.878
NPC1	O15118-1.2	D771Y	Pathogenic	0.868
NPC1	O15118-1.2	F772A	Pathogenic	0.888
NPC1	O15118-1.2	F772C	Pathogenic	0.898
NPC1	O15118-1.2	F772D	Pathogenic	0.875
NPC1	O15118-1.2	F772E	Pathogenic	0.868
NPC1	O15118-1.2	F772G	Pathogenic	0.922
NPC1	O15118-1.2	F772H	Pathogenic	0.788
NPC1	O15118-1.2	F772I	Pathogenic	0.808
NPC1	O15118-1.2	F772K	Pathogenic	0.834
NPC1	O15118-1.2	F772L	Pathogenic	0.804
NPC1	O15118-1.2	F772M	Pathogenic	0.779
NPC1	O15118-1.2	F772N	Pathogenic	0.878
NPC1	O15118-1.2	F772P	Pathogenic	0.945
NPC1	O15118-1.2	F772Q	Pathogenic	0.88
NPC1	O15118-1.2	F772R	Pathogenic	0.844
NPC1	O15118-1.2	F772S	Pathogenic	0.872
NPC1	O15118-1.2	F772T	Pathogenic	0.869
NPC1	O15118-1.2	F772V	Pathogenic	0.852
NPC1	O15118-1.2	F772W	Pathogenic	0.732
NPC1	O15118-1.2	F772Y	Neutral	0.495
NPC1	O15118-1.2	L773A	Neutral	0.36
NPC1	O15118-1.2	L773C	Neutral	0.385
NPC1	O15118-1.2	L773D	Pathogenic	0.52
NPC1	O15118-1.2	L773E	Neutral	0.408
NPC1	O15118-1.2	L773F	Neutral	0.309
NPC1	O15118-1.2	L773G	Pathogenic	0.644
NPC1	O15118-1.2	L773H	Neutral	0.457
NPC1	O15118-1.2	L773I	Neutral	0.161
NPC1	O15118-1.2	L773K	Neutral	0.289
NPC1	O15118-1.2	L773M	Neutral	0.145
NPC1	O15118-1.2	L773N	Neutral	0.43
NPC1	O15118-1.2	L773P	Pathogenic	0.548
NPC1	O15118-1.2	L773Q	Neutral	0.343
NPC1	O15118-1.2	L773R	Neutral	0.305
NPC1	O15118-1.2	L773S	Neutral	0.416
NPC1	O15118-1.2	L773T	Neutral	0.321
NPC1	O15118-1.2	L773V	Neutral	0.218
NPC1	O15118-1.2	L773W	Neutral	0.495
NPC1	O15118-1.2	L773Y	Neutral	0.354
NPC1	O15118-1.2	L774A	Pathogenic	0.729
NPC1	O15118-1.2	L774C	Pathogenic	0.75
NPC1	O15118-1.2	L774D	Pathogenic	0.838
NPC1	O15118-1.2	L774E	Pathogenic	0.767
NPC1	O15118-1.2	L774F	Pathogenic	0.681
NPC1	O15118-1.2	L774G	Pathogenic	0.896
NPC1	O15118-1.2	L774H	Pathogenic	0.801
NPC1	O15118-1.2	L774I	Neutral	0.479
NPC1	O15118-1.2	L774K	Pathogenic	0.66
NPC1	O15118-1.2	L774M	Neutral	0.448
NPC1	O15118-1.2	L774N	Pathogenic	0.783
NPC1	O15118-1.2	L774P	Pathogenic	0.853
NPC1	O15118-1.2	L774Q	Pathogenic	0.714
NPC1	O15118-1.2	L774R	Pathogenic	0.677
NPC1	O15118-1.2	L774S	Pathogenic	0.773
NPC1	O15118-1.2	L774T	Pathogenic	0.693
NPC1	O15118-1.2	L774V	Pathogenic	0.572
NPC1	O15118-1.2	L774W	Pathogenic	0.824
NPC1	O15118-1.2	L774Y	Pathogenic	0.724
NPC1	O15118-1.2	Q775A	Pathogenic	0.873
NPC1	O15118-1.2	Q775C	Pathogenic	0.913
NPC1	O15118-1.2	Q775D	Pathogenic	0.8
NPC1	O15118-1.2	Q775E	Pathogenic	0.634
NPC1	O15118-1.2	Q775F	Pathogenic	0.885
NPC1	O15118-1.2	Q775G	Pathogenic	0.926
NPC1	O15118-1.2	Q775H	Pathogenic	0.792
NPC1	O15118-1.2	Q775I	Pathogenic	0.878
NPC1	O15118-1.2	Q775K	Pathogenic	0.714
NPC1	O15118-1.2	Q775L	Pathogenic	0.835
NPC1	O15118-1.2	Q775M	Pathogenic	0.732
NPC1	O15118-1.2	Q775N	Pathogenic	0.804
NPC1	O15118-1.2	Q775P	Pathogenic	0.839
NPC1	O15118-1.2	Q775R	Pathogenic	0.729
NPC1	O15118-1.2	Q775S	Pathogenic	0.834
NPC1	O15118-1.2	Q775T	Pathogenic	0.856
NPC1	O15118-1.2	Q775V	Pathogenic	0.855
NPC1	O15118-1.2	Q775W	Pathogenic	0.842
NPC1	O15118-1.2	Q775Y	Pathogenic	0.83
NPC1	O15118-1.2	I776A	Neutral	0.48
NPC1	O15118-1.2	I776C	Pathogenic	0.507
NPC1	O15118-1.2	I776D	Pathogenic	0.547
NPC1	O15118-1.2	I776E	Pathogenic	0.531
NPC1	O15118-1.2	I776F	Neutral	0.438
NPC1	O15118-1.2	I776G	Pathogenic	0.749
NPC1	O15118-1.2	I776H	Pathogenic	0.581
NPC1	O15118-1.2	I776K	Neutral	0.496
NPC1	O15118-1.2	I776L	Neutral	0.246
NPC1	O15118-1.2	I776M	Neutral	0.291
NPC1	O15118-1.2	I776N	Pathogenic	0.553
NPC1	O15118-1.2	I776P	Pathogenic	0.666
NPC1	O15118-1.2	I776Q	Pathogenic	0.558
NPC1	O15118-1.2	I776R	Pathogenic	0.514
NPC1	O15118-1.2	I776S	Pathogenic	0.539
NPC1	O15118-1.2	I776T	Neutral	0.437
NPC1	O15118-1.2	I776V	Neutral	0.175
NPC1	O15118-1.2	I776W	Pathogenic	0.717
NPC1	O15118-1.2	I776Y	Neutral	0.474
NPC1	O15118-1.2	T777A	Pathogenic	0.682
NPC1	O15118-1.2	T777C	Pathogenic	0.692
NPC1	O15118-1.2	T777D	Pathogenic	0.663
NPC1	O15118-1.2	T777E	Pathogenic	0.691
NPC1	O15118-1.2	T777F	Pathogenic	0.757
NPC1	O15118-1.2	T777G	Pathogenic	0.829
NPC1	O15118-1.2	T777H	Pathogenic	0.818
NPC1	O15118-1.2	T777I	Pathogenic	0.664
NPC1	O15118-1.2	T777K	Pathogenic	0.7
NPC1	O15118-1.2	T777L	Pathogenic	0.672
NPC1	O15118-1.2	T777M	Pathogenic	0.705
NPC1	O15118-1.2	T777N	Pathogenic	0.588
NPC1	O15118-1.2	T777P	Pathogenic	0.705
NPC1	O15118-1.2	T777Q	Pathogenic	0.726
NPC1	O15118-1.2	T777R	Pathogenic	0.715
NPC1	O15118-1.2	T777S	Pathogenic	0.564
NPC1	O15118-1.2	T777V	Pathogenic	0.593
NPC1	O15118-1.2	T777W	Pathogenic	0.76
NPC1	O15118-1.2	T777Y	Pathogenic	0.81
NPC1	O15118-1.2	C778A	Pathogenic	0.617
NPC1	O15118-1.2	C778D	Pathogenic	0.767
NPC1	O15118-1.2	C778E	Pathogenic	0.849
NPC1	O15118-1.2	C778F	Pathogenic	0.8
NPC1	O15118-1.2	C778G	Pathogenic	0.838
NPC1	O15118-1.2	C778H	Pathogenic	0.839
NPC1	O15118-1.2	C778I	Pathogenic	0.717
NPC1	O15118-1.2	C778K	Pathogenic	0.8
NPC1	O15118-1.2	C778L	Pathogenic	0.724
NPC1	O15118-1.2	C778M	Pathogenic	0.754
NPC1	O15118-1.2	C778N	Pathogenic	0.782
NPC1	O15118-1.2	C778P	Pathogenic	0.843
NPC1	O15118-1.2	C778Q	Pathogenic	0.82
NPC1	O15118-1.2	C778R	Pathogenic	0.811
NPC1	O15118-1.2	C778S	Pathogenic	0.671
NPC1	O15118-1.2	C778T	Pathogenic	0.684
NPC1	O15118-1.2	C778V	Pathogenic	0.733
NPC1	O15118-1.2	C778W	Pathogenic	0.802
NPC1	O15118-1.2	C778Y	Pathogenic	0.843
NPC1	O15118-1.2	F779A	Pathogenic	0.883
NPC1	O15118-1.2	F779C	Pathogenic	0.893
NPC1	O15118-1.2	F779D	Pathogenic	0.87
NPC1	O15118-1.2	F779E	Pathogenic	0.862
NPC1	O15118-1.2	F779G	Pathogenic	0.918
NPC1	O15118-1.2	F779H	Pathogenic	0.78
NPC1	O15118-1.2	F779I	Pathogenic	0.8
NPC1	O15118-1.2	F779K	Pathogenic	0.826
NPC1	O15118-1.2	F779L	Pathogenic	0.796
NPC1	O15118-1.2	F779M	Pathogenic	0.77
NPC1	O15118-1.2	F779N	Pathogenic	0.873
NPC1	O15118-1.2	F779P	Pathogenic	0.942
NPC1	O15118-1.2	F779Q	Pathogenic	0.875
NPC1	O15118-1.2	F779R	Pathogenic	0.837
NPC1	O15118-1.2	F779S	Pathogenic	0.866
NPC1	O15118-1.2	F779T	Pathogenic	0.863
NPC1	O15118-1.2	F779V	Pathogenic	0.846
NPC1	O15118-1.2	F779W	Pathogenic	0.722
NPC1	O15118-1.2	F779Y	Neutral	0.482
NPC1	O15118-1.2	V780A	Pathogenic	0.581
NPC1	O15118-1.2	V780C	Pathogenic	0.695
NPC1	O15118-1.2	V780D	Pathogenic	0.728
NPC1	O15118-1.2	V780E	Pathogenic	0.641
NPC1	O15118-1.2	V780F	Pathogenic	0.685
NPC1	O15118-1.2	V780G	Pathogenic	0.817
NPC1	O15118-1.2	V780H	Pathogenic	0.782
NPC1	O15118-1.2	V780I	Neutral	0.302
NPC1	O15118-1.2	V780K	Pathogenic	0.65
NPC1	O15118-1.2	V780L	Neutral	0.492
NPC1	O15118-1.2	V780M	Pathogenic	0.531
NPC1	O15118-1.2	V780N	Pathogenic	0.733
NPC1	O15118-1.2	V780P	Pathogenic	0.75
NPC1	O15118-1.2	V780Q	Pathogenic	0.679
NPC1	O15118-1.2	V780R	Pathogenic	0.746
NPC1	O15118-1.2	V780S	Pathogenic	0.721
NPC1	O15118-1.2	V780T	Pathogenic	0.538
NPC1	O15118-1.2	V780W	Pathogenic	0.827
NPC1	O15118-1.2	V780Y	Pathogenic	0.715
NPC1	O15118-1.2	S781A	Pathogenic	0.718
NPC1	O15118-1.2	S781C	Pathogenic	0.821
NPC1	O15118-1.2	S781D	Pathogenic	0.78
NPC1	O15118-1.2	S781E	Pathogenic	0.805
NPC1	O15118-1.2	S781F	Pathogenic	0.874
NPC1	O15118-1.2	S781G	Pathogenic	0.823
NPC1	O15118-1.2	S781H	Pathogenic	0.881
NPC1	O15118-1.2	S781I	Pathogenic	0.866
NPC1	O15118-1.2	S781K	Pathogenic	0.811
NPC1	O15118-1.2	S781L	Pathogenic	0.87
NPC1	O15118-1.2	S781M	Pathogenic	0.842
NPC1	O15118-1.2	S781N	Pathogenic	0.724
NPC1	O15118-1.2	S781P	Pathogenic	0.837
NPC1	O15118-1.2	S781Q	Pathogenic	0.83
NPC1	O15118-1.2	S781R	Pathogenic	0.872
NPC1	O15118-1.2	S781T	Pathogenic	0.738
NPC1	O15118-1.2	S781V	Pathogenic	0.875
NPC1	O15118-1.2	S781W	Pathogenic	0.912
NPC1	O15118-1.2	S781Y	Pathogenic	0.905
NPC1	O15118-1.2	L782A	Pathogenic	0.881
NPC1	O15118-1.2	L782C	Pathogenic	0.892
NPC1	O15118-1.2	L782D	Pathogenic	0.935
NPC1	O15118-1.2	L782E	Pathogenic	0.901
NPC1	O15118-1.2	L782F	Pathogenic	0.855
NPC1	O15118-1.2	L782G	Pathogenic	0.96
NPC1	O15118-1.2	L782H	Pathogenic	0.918
NPC1	O15118-1.2	L782I	Pathogenic	0.718
NPC1	O15118-1.2	L782K	Pathogenic	0.843
NPC1	O15118-1.2	L782M	Pathogenic	0.692
NPC1	O15118-1.2	L782N	Pathogenic	0.909
NPC1	O15118-1.2	L782P	Pathogenic	0.941
NPC1	O15118-1.2	L782Q	Pathogenic	0.873
NPC1	O15118-1.2	L782R	Pathogenic	0.853
NPC1	O15118-1.2	L782S	Pathogenic	0.904
NPC1	O15118-1.2	L782T	Pathogenic	0.862
NPC1	O15118-1.2	L782V	Pathogenic	0.787
NPC1	O15118-1.2	L782W	Pathogenic	0.928
NPC1	O15118-1.2	L782Y	Pathogenic	0.879
NPC1	O15118-1.2	L783A	Pathogenic	0.842
NPC1	O15118-1.2	L783C	Pathogenic	0.856
NPC1	O15118-1.2	L783D	Pathogenic	0.911
NPC1	O15118-1.2	L783E	Pathogenic	0.868
NPC1	O15118-1.2	L783F	Pathogenic	0.809
NPC1	O15118-1.2	L783G	Pathogenic	0.945
NPC1	O15118-1.2	L783H	Pathogenic	0.889
NPC1	O15118-1.2	L783I	Pathogenic	0.646
NPC1	O15118-1.2	L783K	Pathogenic	0.795
NPC1	O15118-1.2	L783M	Pathogenic	0.618
NPC1	O15118-1.2	L783N	Pathogenic	0.878
NPC1	O15118-1.2	L783P	Pathogenic	0.92
NPC1	O15118-1.2	L783Q	Pathogenic	0.832
NPC1	O15118-1.2	L783R	Pathogenic	0.806
NPC1	O15118-1.2	L783S	Pathogenic	0.871
NPC1	O15118-1.2	L783T	Pathogenic	0.818
NPC1	O15118-1.2	L783V	Pathogenic	0.726
NPC1	O15118-1.2	L783W	Pathogenic	0.903
NPC1	O15118-1.2	L783Y	Pathogenic	0.839
NPC1	O15118-1.2	G784A	Neutral	0.465
NPC1	O15118-1.2	G784C	Pathogenic	0.713
NPC1	O15118-1.2	G784D	Pathogenic	0.559
NPC1	O15118-1.2	G784E	Pathogenic	0.685
NPC1	O15118-1.2	G784F	Pathogenic	0.719
NPC1	O15118-1.2	G784H	Pathogenic	0.731
NPC1	O15118-1.2	G784I	Pathogenic	0.778
NPC1	O15118-1.2	G784K	Pathogenic	0.694
NPC1	O15118-1.2	G784L	Pathogenic	0.784
NPC1	O15118-1.2	G784M	Pathogenic	0.742
NPC1	O15118-1.2	G784N	Neutral	0.485
NPC1	O15118-1.2	G784P	Pathogenic	0.654
NPC1	O15118-1.2	G784Q	Pathogenic	0.72
NPC1	O15118-1.2	G784R	Pathogenic	0.709
NPC1	O15118-1.2	G784S	Neutral	0.497
NPC1	O15118-1.2	G784T	Pathogenic	0.692
NPC1	O15118-1.2	G784V	Pathogenic	0.72
NPC1	O15118-1.2	G784W	Pathogenic	0.638
NPC1	O15118-1.2	G784Y	Pathogenic	0.777
NPC1	O15118-1.2	L785A	Pathogenic	0.921
NPC1	O15118-1.2	L785C	Pathogenic	0.928
NPC1	O15118-1.2	L785D	Pathogenic	0.957
NPC1	O15118-1.2	L785E	Pathogenic	0.934
NPC1	O15118-1.2	L785F	Pathogenic	0.902
NPC1	O15118-1.2	L785G	Pathogenic	0.974
NPC1	O15118-1.2	L785H	Pathogenic	0.946
NPC1	O15118-1.2	L785I	Pathogenic	0.799
NPC1	O15118-1.2	L785K	Pathogenic	0.894
NPC1	O15118-1.2	L785M	Pathogenic	0.778
NPC1	O15118-1.2	L785N	Pathogenic	0.94
NPC1	O15118-1.2	L785P	Pathogenic	0.962
NPC1	O15118-1.2	L785Q	Pathogenic	0.915
NPC1	O15118-1.2	L785R	Pathogenic	0.9
NPC1	O15118-1.2	L785S	Pathogenic	0.936
NPC1	O15118-1.2	L785T	Pathogenic	0.907
NPC1	O15118-1.2	L785V	Pathogenic	0.852
NPC1	O15118-1.2	L785W	Pathogenic	0.953
NPC1	O15118-1.2	L785Y	Pathogenic	0.919
NPC1	O15118-1.2	D786A	Pathogenic	0.968
NPC1	O15118-1.2	D786C	Pathogenic	0.97
NPC1	O15118-1.2	D786E	Pathogenic	0.896
NPC1	O15118-1.2	D786F	Pathogenic	0.969
NPC1	O15118-1.2	D786G	Pathogenic	0.963
NPC1	O15118-1.2	D786H	Pathogenic	0.957
NPC1	O15118-1.2	D786I	Pathogenic	0.967
NPC1	O15118-1.2	D786K	Pathogenic	0.969
NPC1	O15118-1.2	D786L	Pathogenic	0.978
NPC1	O15118-1.2	D786M	Pathogenic	0.972
NPC1	O15118-1.2	D786N	Pathogenic	0.921
NPC1	O15118-1.2	D786P	Pathogenic	0.94
NPC1	O15118-1.2	D786Q	Pathogenic	0.944
NPC1	O15118-1.2	D786R	Pathogenic	0.98
NPC1	O15118-1.2	D786S	Pathogenic	0.939
NPC1	O15118-1.2	D786T	Pathogenic	0.949
NPC1	O15118-1.2	D786V	Pathogenic	0.969
NPC1	O15118-1.2	D786W	Pathogenic	0.979
NPC1	O15118-1.2	D786Y	Pathogenic	0.977
NPC1	O15118-1.2	I787A	Neutral	0.453
NPC1	O15118-1.2	I787C	Neutral	0.48
NPC1	O15118-1.2	I787D	Pathogenic	0.52
NPC1	O15118-1.2	I787E	Pathogenic	0.504
NPC1	O15118-1.2	I787F	Neutral	0.411
NPC1	O15118-1.2	I787G	Pathogenic	0.727
NPC1	O15118-1.2	I787H	Pathogenic	0.554
NPC1	O15118-1.2	I787K	Neutral	0.468
NPC1	O15118-1.2	I787L	Neutral	0.227
NPC1	O15118-1.2	I787M	Neutral	0.269
NPC1	O15118-1.2	I787N	Pathogenic	0.526
NPC1	O15118-1.2	I787P	Pathogenic	0.641
NPC1	O15118-1.2	I787Q	Pathogenic	0.531
NPC1	O15118-1.2	I787R	Neutral	0.487
NPC1	O15118-1.2	I787S	Pathogenic	0.512
NPC1	O15118-1.2	I787T	Neutral	0.41
NPC1	O15118-1.2	I787V	Neutral	0.16
NPC1	O15118-1.2	I787W	Pathogenic	0.695
NPC1	O15118-1.2	I787Y	Neutral	0.447
NPC1	O15118-1.2	K788A	Pathogenic	0.621
NPC1	O15118-1.2	K788C	Pathogenic	0.716
NPC1	O15118-1.2	K788D	Pathogenic	0.669
NPC1	O15118-1.2	K788E	Neutral	0.445
NPC1	O15118-1.2	K788F	Pathogenic	0.589
NPC1	O15118-1.2	K788G	Pathogenic	0.749
NPC1	O15118-1.2	K788H	Pathogenic	0.56
NPC1	O15118-1.2	K788I	Pathogenic	0.604
NPC1	O15118-1.2	K788L	Pathogenic	0.517
NPC1	O15118-1.2	K788M	Neutral	0.46
NPC1	O15118-1.2	K788N	Pathogenic	0.558
NPC1	O15118-1.2	K788P	Pathogenic	0.554
NPC1	O15118-1.2	K788Q	Neutral	0.404
NPC1	O15118-1.2	K788R	Neutral	0.361
NPC1	O15118-1.2	K788S	Pathogenic	0.546
NPC1	O15118-1.2	K788T	Pathogenic	0.587
NPC1	O15118-1.2	K788V	Pathogenic	0.586
NPC1	O15118-1.2	K788W	Pathogenic	0.593
NPC1	O15118-1.2	K788Y	Pathogenic	0.571
NPC1	O15118-1.2	R789A	Pathogenic	0.968
NPC1	O15118-1.2	R789C	Pathogenic	0.979
NPC1	O15118-1.2	R789D	Pathogenic	0.982
NPC1	O15118-1.2	R789E	Pathogenic	0.956
NPC1	O15118-1.2	R789F	Pathogenic	0.964
NPC1	O15118-1.2	R789G	Pathogenic	0.982
NPC1	O15118-1.2	R789H	Pathogenic	0.941
NPC1	O15118-1.2	R789I	Pathogenic	0.966
NPC1	O15118-1.2	R789K	Pathogenic	0.906
NPC1	O15118-1.2	R789L	Pathogenic	0.952
NPC1	O15118-1.2	R789M	Pathogenic	0.94
NPC1	O15118-1.2	R789N	Pathogenic	0.959
NPC1	O15118-1.2	R789P	Pathogenic	0.971
NPC1	O15118-1.2	R789Q	Pathogenic	0.926
NPC1	O15118-1.2	R789S	Pathogenic	0.97
NPC1	O15118-1.2	R789T	Pathogenic	0.963
NPC1	O15118-1.2	R789V	Pathogenic	0.975
NPC1	O15118-1.2	R789W	Pathogenic	0.958
NPC1	O15118-1.2	R789Y	Pathogenic	0.958
NPC1	O15118-1.2	Q790A	Pathogenic	0.919
NPC1	O15118-1.2	Q790C	Pathogenic	0.946
NPC1	O15118-1.2	Q790D	Pathogenic	0.869
NPC1	O15118-1.2	Q790E	Pathogenic	0.742
NPC1	O15118-1.2	Q790F	Pathogenic	0.928
NPC1	O15118-1.2	Q790G	Pathogenic	0.954
NPC1	O15118-1.2	Q790H	Pathogenic	0.864
NPC1	O15118-1.2	Q790I	Pathogenic	0.923
NPC1	O15118-1.2	Q790K	Pathogenic	0.806
NPC1	O15118-1.2	Q790L	Pathogenic	0.894
NPC1	O15118-1.2	Q790M	Pathogenic	0.82
NPC1	O15118-1.2	Q790N	Pathogenic	0.872
NPC1	O15118-1.2	Q790P	Pathogenic	0.896
NPC1	O15118-1.2	Q790R	Pathogenic	0.817
NPC1	O15118-1.2	Q790S	Pathogenic	0.893
NPC1	O15118-1.2	Q790T	Pathogenic	0.908
NPC1	O15118-1.2	Q790V	Pathogenic	0.908
NPC1	O15118-1.2	Q790W	Pathogenic	0.899
NPC1	O15118-1.2	Q790Y	Pathogenic	0.89
NPC1	O15118-1.2	E791A	Pathogenic	0.693
NPC1	O15118-1.2	E791C	Pathogenic	0.837
NPC1	O15118-1.2	E791D	Neutral	0.446
NPC1	O15118-1.2	E791F	Pathogenic	0.73
NPC1	O15118-1.2	E791G	Pathogenic	0.805
NPC1	O15118-1.2	E791H	Pathogenic	0.571
NPC1	O15118-1.2	E791I	Pathogenic	0.716
NPC1	O15118-1.2	E791K	Pathogenic	0.536
NPC1	O15118-1.2	E791L	Pathogenic	0.723
NPC1	O15118-1.2	E791M	Pathogenic	0.675
NPC1	O15118-1.2	E791N	Pathogenic	0.635
NPC1	O15118-1.2	E791P	Pathogenic	0.631
NPC1	O15118-1.2	E791Q	Neutral	0.403
NPC1	O15118-1.2	E791R	Pathogenic	0.646
NPC1	O15118-1.2	E791S	Pathogenic	0.624
NPC1	O15118-1.2	E791T	Pathogenic	0.662
NPC1	O15118-1.2	E791V	Pathogenic	0.661
NPC1	O15118-1.2	E791W	Pathogenic	0.734
NPC1	O15118-1.2	E791Y	Pathogenic	0.716
NPC1	O15118-1.2	K792A	Neutral	0.283
NPC1	O15118-1.2	K792C	Neutral	0.379
NPC1	O15118-1.2	K792D	Neutral	0.329
NPC1	O15118-1.2	K792E	Neutral	0.163
NPC1	O15118-1.2	K792F	Neutral	0.257
NPC1	O15118-1.2	K792G	Neutral	0.42
NPC1	O15118-1.2	K792H	Neutral	0.235
NPC1	O15118-1.2	K792I	Neutral	0.269
NPC1	O15118-1.2	K792L	Neutral	0.206
NPC1	O15118-1.2	K792M	Neutral	0.171
NPC1	O15118-1.2	K792N	Neutral	0.234
NPC1	O15118-1.2	K792P	Neutral	0.231
NPC1	O15118-1.2	K792Q	Neutral	0.141
NPC1	O15118-1.2	K792R	Neutral	0.12
NPC1	O15118-1.2	K792S	Neutral	0.225
NPC1	O15118-1.2	K792T	Neutral	0.256
NPC1	O15118-1.2	K792V	Neutral	0.255
NPC1	O15118-1.2	K792W	Neutral	0.26
NPC1	O15118-1.2	K792Y	Neutral	0.243
NPC1	O15118-1.2	N793A	Pathogenic	0.915
NPC1	O15118-1.2	N793C	Pathogenic	0.919
NPC1	O15118-1.2	N793D	Pathogenic	0.789
NPC1	O15118-1.2	N793E	Pathogenic	0.858
NPC1	O15118-1.2	N793F	Pathogenic	0.911
NPC1	O15118-1.2	N793G	Pathogenic	0.861
NPC1	O15118-1.2	N793H	Pathogenic	0.775
NPC1	O15118-1.2	N793I	Pathogenic	0.906
NPC1	O15118-1.2	N793K	Pathogenic	0.863
NPC1	O15118-1.2	N793L	Pathogenic	0.908
NPC1	O15118-1.2	N793M	Pathogenic	0.887
NPC1	O15118-1.2	N793P	Pathogenic	0.891
NPC1	O15118-1.2	N793Q	Pathogenic	0.847
NPC1	O15118-1.2	N793R	Pathogenic	0.871
NPC1	O15118-1.2	N793S	Pathogenic	0.786
NPC1	O15118-1.2	N793T	Pathogenic	0.812
NPC1	O15118-1.2	N793V	Pathogenic	0.912
NPC1	O15118-1.2	N793W	Pathogenic	0.939
NPC1	O15118-1.2	N793Y	Pathogenic	0.905
NPC1	O15118-1.2	R794A	Pathogenic	0.906
NPC1	O15118-1.2	R794C	Pathogenic	0.937
NPC1	O15118-1.2	R794D	Pathogenic	0.946
NPC1	O15118-1.2	R794E	Pathogenic	0.874
NPC1	O15118-1.2	R794F	Pathogenic	0.894
NPC1	O15118-1.2	R794G	Pathogenic	0.946
NPC1	O15118-1.2	R794H	Pathogenic	0.836
NPC1	O15118-1.2	R794I	Pathogenic	0.9
NPC1	O15118-1.2	R794K	Pathogenic	0.756
NPC1	O15118-1.2	R794L	Pathogenic	0.863
NPC1	O15118-1.2	R794M	Pathogenic	0.834
NPC1	O15118-1.2	R794N	Pathogenic	0.882
NPC1	O15118-1.2	R794P	Pathogenic	0.915
NPC1	O15118-1.2	R794Q	Pathogenic	0.8
NPC1	O15118-1.2	R794S	Pathogenic	0.912
NPC1	O15118-1.2	R794T	Pathogenic	0.893
NPC1	O15118-1.2	R794V	Pathogenic	0.925
NPC1	O15118-1.2	R794W	Pathogenic	0.88
NPC1	O15118-1.2	R794Y	Pathogenic	0.879
NPC1	O15118-1.2	L795A	Pathogenic	0.597
NPC1	O15118-1.2	L795C	Pathogenic	0.623
NPC1	O15118-1.2	L795D	Pathogenic	0.741
NPC1	O15118-1.2	L795E	Pathogenic	0.645
NPC1	O15118-1.2	L795F	Pathogenic	0.541
NPC1	O15118-1.2	L795G	Pathogenic	0.827
NPC1	O15118-1.2	L795H	Pathogenic	0.69
NPC1	O15118-1.2	L795I	Neutral	0.337
NPC1	O15118-1.2	L795K	Pathogenic	0.518
NPC1	O15118-1.2	L795M	Neutral	0.31
NPC1	O15118-1.2	L795N	Pathogenic	0.666
NPC1	O15118-1.2	L795P	Pathogenic	0.762
NPC1	O15118-1.2	L795Q	Pathogenic	0.579
NPC1	O15118-1.2	L795R	Pathogenic	0.536
NPC1	O15118-1.2	L795S	Pathogenic	0.652
NPC1	O15118-1.2	L795T	Pathogenic	0.555
NPC1	O15118-1.2	L795V	Neutral	0.424
NPC1	O15118-1.2	L795W	Pathogenic	0.721
NPC1	O15118-1.2	L795Y	Pathogenic	0.591
NPC1	O15118-1.2	D796A	Pathogenic	0.946
NPC1	O15118-1.2	D796C	Pathogenic	0.949
NPC1	O15118-1.2	D796E	Pathogenic	0.833
NPC1	O15118-1.2	D796F	Pathogenic	0.947
NPC1	O15118-1.2	D796G	Pathogenic	0.937
NPC1	O15118-1.2	D796H	Pathogenic	0.928
NPC1	O15118-1.2	D796I	Pathogenic	0.943
NPC1	O15118-1.2	D796K	Pathogenic	0.947
NPC1	O15118-1.2	D796L	Pathogenic	0.962
NPC1	O15118-1.2	D796M	Pathogenic	0.953
NPC1	O15118-1.2	D796N	Pathogenic	0.87
NPC1	O15118-1.2	D796P	Pathogenic	0.901
NPC1	O15118-1.2	D796Q	Pathogenic	0.906
NPC1	O15118-1.2	D796R	Pathogenic	0.966
NPC1	O15118-1.2	D796S	Pathogenic	0.898
NPC1	O15118-1.2	D796T	Pathogenic	0.915
NPC1	O15118-1.2	D796V	Pathogenic	0.948
NPC1	O15118-1.2	D796W	Pathogenic	0.964
NPC1	O15118-1.2	D796Y	Pathogenic	0.961
NPC1	O15118-1.2	I797A	Pathogenic	0.662
NPC1	O15118-1.2	I797C	Pathogenic	0.686
NPC1	O15118-1.2	I797D	Pathogenic	0.719
NPC1	O15118-1.2	I797E	Pathogenic	0.706
NPC1	O15118-1.2	I797F	Pathogenic	0.623
NPC1	O15118-1.2	I797G	Pathogenic	0.863
NPC1	O15118-1.2	I797H	Pathogenic	0.746
NPC1	O15118-1.2	I797K	Pathogenic	0.676
NPC1	O15118-1.2	I797L	Neutral	0.409
NPC1	O15118-1.2	I797M	Neutral	0.466
NPC1	O15118-1.2	I797N	Pathogenic	0.725
NPC1	O15118-1.2	I797P	Pathogenic	0.809
NPC1	O15118-1.2	I797Q	Pathogenic	0.728
NPC1	O15118-1.2	I797R	Pathogenic	0.692
NPC1	O15118-1.2	I797S	Pathogenic	0.713
NPC1	O15118-1.2	I797T	Pathogenic	0.622
NPC1	O15118-1.2	I797V	Neutral	0.31
NPC1	O15118-1.2	I797W	Pathogenic	0.843
NPC1	O15118-1.2	I797Y	Pathogenic	0.657
NPC1	O15118-1.2	F798A	Pathogenic	0.516
NPC1	O15118-1.2	F798C	Pathogenic	0.543
NPC1	O15118-1.2	F798D	Neutral	0.487
NPC1	O15118-1.2	F798E	Neutral	0.47
NPC1	O15118-1.2	F798G	Pathogenic	0.614
NPC1	O15118-1.2	F798H	Neutral	0.334
NPC1	O15118-1.2	F798I	Neutral	0.362
NPC1	O15118-1.2	F798K	Neutral	0.403
NPC1	O15118-1.2	F798L	Neutral	0.357
NPC1	O15118-1.2	F798M	Neutral	0.322
NPC1	O15118-1.2	F798N	Neutral	0.493
NPC1	O15118-1.2	F798P	Pathogenic	0.697
NPC1	O15118-1.2	F798Q	Neutral	0.498
NPC1	O15118-1.2	F798R	Neutral	0.421
NPC1	O15118-1.2	F798S	Neutral	0.478
NPC1	O15118-1.2	F798T	Neutral	0.472
NPC1	O15118-1.2	F798V	Neutral	0.438
NPC1	O15118-1.2	F798W	Neutral	0.27
NPC1	O15118-1.2	F798Y	Neutral	0.117
NPC1	O15118-1.2	C799A	Pathogenic	0.943
NPC1	O15118-1.2	C799D	Pathogenic	0.971
NPC1	O15118-1.2	C799E	Pathogenic	0.983
NPC1	O15118-1.2	C799F	Pathogenic	0.976
NPC1	O15118-1.2	C799G	Pathogenic	0.982
NPC1	O15118-1.2	C799H	Pathogenic	0.982
NPC1	O15118-1.2	C799I	Pathogenic	0.963
NPC1	O15118-1.2	C799K	Pathogenic	0.976
NPC1	O15118-1.2	C799L	Pathogenic	0.964
NPC1	O15118-1.2	C799M	Pathogenic	0.969
NPC1	O15118-1.2	C799N	Pathogenic	0.974
NPC1	O15118-1.2	C799P	Pathogenic	0.982
NPC1	O15118-1.2	C799Q	Pathogenic	0.979
NPC1	O15118-1.2	C799R	Pathogenic	0.978
NPC1	O15118-1.2	C799S	Pathogenic	0.955
NPC1	O15118-1.2	C799T	Pathogenic	0.957
NPC1	O15118-1.2	C799V	Pathogenic	0.966
NPC1	O15118-1.2	C799W	Pathogenic	0.977
NPC1	O15118-1.2	C799Y	Pathogenic	0.982
NPC1	O15118-1.2	C800A	Pathogenic	0.835
NPC1	O15118-1.2	C800D	Pathogenic	0.912
NPC1	O15118-1.2	C800E	Pathogenic	0.947
NPC1	O15118-1.2	C800F	Pathogenic	0.926
NPC1	O15118-1.2	C800G	Pathogenic	0.942
NPC1	O15118-1.2	C800H	Pathogenic	0.943
NPC1	O15118-1.2	C800I	Pathogenic	0.889
NPC1	O15118-1.2	C800K	Pathogenic	0.926
NPC1	O15118-1.2	C800L	Pathogenic	0.892
NPC1	O15118-1.2	C800M	Pathogenic	0.906
NPC1	O15118-1.2	C800N	Pathogenic	0.919
NPC1	O15118-1.2	C800P	Pathogenic	0.944
NPC1	O15118-1.2	C800Q	Pathogenic	0.935
NPC1	O15118-1.2	C800R	Pathogenic	0.931
NPC1	O15118-1.2	C800S	Pathogenic	0.865
NPC1	O15118-1.2	C800T	Pathogenic	0.872
NPC1	O15118-1.2	C800V	Pathogenic	0.896
NPC1	O15118-1.2	C800W	Pathogenic	0.928
NPC1	O15118-1.2	C800Y	Pathogenic	0.944
NPC1	O15118-1.2	V801A	Neutral	0.475
NPC1	O15118-1.2	V801C	Pathogenic	0.598
NPC1	O15118-1.2	V801D	Pathogenic	0.635
NPC1	O15118-1.2	V801E	Pathogenic	0.538
NPC1	O15118-1.2	V801F	Pathogenic	0.587
NPC1	O15118-1.2	V801G	Pathogenic	0.745
NPC1	O15118-1.2	V801H	Pathogenic	0.7
NPC1	O15118-1.2	V801I	Neutral	0.22
NPC1	O15118-1.2	V801K	Pathogenic	0.548
NPC1	O15118-1.2	V801L	Neutral	0.388
NPC1	O15118-1.2	V801M	Neutral	0.425
NPC1	O15118-1.2	V801N	Pathogenic	0.641
NPC1	O15118-1.2	V801P	Pathogenic	0.662
NPC1	O15118-1.2	V801Q	Pathogenic	0.58
NPC1	O15118-1.2	V801R	Pathogenic	0.658
NPC1	O15118-1.2	V801S	Pathogenic	0.628
NPC1	O15118-1.2	V801T	Neutral	0.432
NPC1	O15118-1.2	V801W	Pathogenic	0.757
NPC1	O15118-1.2	V801Y	Pathogenic	0.621
NPC1	O15118-1.2	R802A	Neutral	0.454
NPC1	O15118-1.2	R802C	Pathogenic	0.561
NPC1	O15118-1.2	R802D	Pathogenic	0.602
NPC1	O15118-1.2	R802E	Neutral	0.375
NPC1	O15118-1.2	R802F	Neutral	0.421
NPC1	O15118-1.2	R802G	Pathogenic	0.603
NPC1	O15118-1.2	R802H	Neutral	0.305
NPC1	O15118-1.2	R802I	Neutral	0.436
NPC1	O15118-1.2	R802K	Neutral	0.21
NPC1	O15118-1.2	R802L	Neutral	0.353
NPC1	O15118-1.2	R802M	Neutral	0.302
NPC1	O15118-1.2	R802N	Neutral	0.391
NPC1	O15118-1.2	R802P	Neutral	0.481
NPC1	O15118-1.2	R802Q	Neutral	0.256
NPC1	O15118-1.2	R802S	Neutral	0.473
NPC1	O15118-1.2	R802T	Neutral	0.419
NPC1	O15118-1.2	R802V	Pathogenic	0.513
NPC1	O15118-1.2	R802W	Neutral	0.387
NPC1	O15118-1.2	R802Y	Neutral	0.386
NPC1	O15118-1.2	G803A	Neutral	0.338
NPC1	O15118-1.2	G803C	Pathogenic	0.593
NPC1	O15118-1.2	G803D	Neutral	0.427
NPC1	O15118-1.2	G803E	Pathogenic	0.561
NPC1	O15118-1.2	G803F	Pathogenic	0.6
NPC1	O15118-1.2	G803H	Pathogenic	0.615
NPC1	O15118-1.2	G803I	Pathogenic	0.672
NPC1	O15118-1.2	G803K	Pathogenic	0.571
NPC1	O15118-1.2	G803L	Pathogenic	0.68
NPC1	O15118-1.2	G803M	Pathogenic	0.628
NPC1	O15118-1.2	G803N	Neutral	0.356
NPC1	O15118-1.2	G803P	Pathogenic	0.526
NPC1	O15118-1.2	G803Q	Pathogenic	0.602
NPC1	O15118-1.2	G803R	Pathogenic	0.589
NPC1	O15118-1.2	G803S	Neutral	0.367
NPC1	O15118-1.2	G803T	Pathogenic	0.568
NPC1	O15118-1.2	G803V	Pathogenic	0.602
NPC1	O15118-1.2	G803W	Pathogenic	0.509
NPC1	O15118-1.2	G803Y	Pathogenic	0.672
NPC1	O15118-1.2	A804C	Neutral	0.146
NPC1	O15118-1.2	A804D	Neutral	0.251
NPC1	O15118-1.2	A804E	Neutral	0.209
NPC1	O15118-1.2	A804F	Neutral	0.276
NPC1	O15118-1.2	A804G	Neutral	0.162
NPC1	O15118-1.2	A804H	Neutral	0.347
NPC1	O15118-1.2	A804I	Neutral	0.195
NPC1	O15118-1.2	A804K	Neutral	0.216
NPC1	O15118-1.2	A804L	Neutral	0.2
NPC1	O15118-1.2	A804M	Neutral	0.226
NPC1	O15118-1.2	A804N	Neutral	0.267
NPC1	O15118-1.2	A804P	Neutral	0.22
NPC1	O15118-1.2	A804Q	Neutral	0.239
NPC1	O15118-1.2	A804R	Neutral	0.229
NPC1	O15118-1.2	A804S	Neutral	0.107
NPC1	O15118-1.2	A804T	Neutral	0.18
NPC1	O15118-1.2	A804V	Neutral	0.151
NPC1	O15118-1.2	A804W	Neutral	0.363
NPC1	O15118-1.2	A804Y	Neutral	0.343
NPC1	O15118-1.2	E805A	Neutral	0.367
NPC1	O15118-1.2	E805C	Pathogenic	0.568
NPC1	O15118-1.2	E805D	Neutral	0.171
NPC1	O15118-1.2	E805F	Neutral	0.41
NPC1	O15118-1.2	E805G	Pathogenic	0.514
NPC1	O15118-1.2	E805H	Neutral	0.255
NPC1	O15118-1.2	E805I	Neutral	0.393
NPC1	O15118-1.2	E805K	Neutral	0.229
NPC1	O15118-1.2	E805L	Neutral	0.401
NPC1	O15118-1.2	E805M	Neutral	0.347
NPC1	O15118-1.2	E805N	Neutral	0.309
NPC1	O15118-1.2	E805P	Neutral	0.305
NPC1	O15118-1.2	E805Q	Neutral	0.148
NPC1	O15118-1.2	E805R	Neutral	0.319
NPC1	O15118-1.2	E805S	Neutral	0.299
NPC1	O15118-1.2	E805T	Neutral	0.335
NPC1	O15118-1.2	E805V	Neutral	0.334
NPC1	O15118-1.2	E805W	Neutral	0.414
NPC1	O15118-1.2	E805Y	Neutral	0.392
NPC1	O15118-1.2	D806A	Neutral	0.345
NPC1	O15118-1.2	D806C	Neutral	0.356
NPC1	O15118-1.2	D806E	Neutral	0.129
NPC1	O15118-1.2	D806F	Neutral	0.348
NPC1	O15118-1.2	D806G	Neutral	0.308
NPC1	O15118-1.2	D806H	Neutral	0.279
NPC1	O15118-1.2	D806I	Neutral	0.332
NPC1	O15118-1.2	D806K	Neutral	0.35
NPC1	O15118-1.2	D806L	Neutral	0.431
NPC1	O15118-1.2	D806M	Neutral	0.376
NPC1	O15118-1.2	D806N	Neutral	0.166
NPC1	O15118-1.2	D806P	Neutral	0.214
NPC1	O15118-1.2	D806Q	Neutral	0.224
NPC1	O15118-1.2	D806R	Neutral	0.46
NPC1	O15118-1.2	D806S	Neutral	0.209
NPC1	O15118-1.2	D806T	Neutral	0.242
NPC1	O15118-1.2	D806V	Neutral	0.35
NPC1	O15118-1.2	D806W	Neutral	0.444
NPC1	O15118-1.2	D806Y	Neutral	0.422
NPC1	O15118-1.2	G807A	Neutral	0.152
NPC1	O15118-1.2	G807C	Neutral	0.338
NPC1	O15118-1.2	G807D	Neutral	0.207
NPC1	O15118-1.2	G807E	Neutral	0.309
NPC1	O15118-1.2	G807F	Neutral	0.344
NPC1	O15118-1.2	G807H	Neutral	0.358
NPC1	O15118-1.2	G807I	Neutral	0.418
NPC1	O15118-1.2	G807K	Neutral	0.318
NPC1	O15118-1.2	G807L	Neutral	0.427
NPC1	O15118-1.2	G807M	Neutral	0.372
NPC1	O15118-1.2	G807N	Neutral	0.162
NPC1	O15118-1.2	G807P	Neutral	0.28
NPC1	O15118-1.2	G807Q	Neutral	0.346
NPC1	O15118-1.2	G807R	Neutral	0.334
NPC1	O15118-1.2	G807S	Neutral	0.169
NPC1	O15118-1.2	G807T	Neutral	0.315
NPC1	O15118-1.2	G807V	Neutral	0.346
NPC1	O15118-1.2	G807W	Neutral	0.266
NPC1	O15118-1.2	G807Y	Neutral	0.418
NPC1	O15118-1.2	T808A	Neutral	0.088
NPC1	O15118-1.2	T808C	Neutral	0.091
NPC1	O15118-1.2	T808D	Neutral	0.081
NPC1	O15118-1.2	T808E	Neutral	0.091
NPC1	O15118-1.2	T808F	Neutral	0.123
NPC1	O15118-1.2	T808G	Neutral	0.179
NPC1	O15118-1.2	T808H	Neutral	0.168
NPC1	O15118-1.2	T808I	Neutral	0.081
NPC1	O15118-1.2	T808K	Neutral	0.095
NPC1	O15118-1.2	T808L	Neutral	0.084
NPC1	O15118-1.2	T808M	Neutral	0.097
NPC1	O15118-1.2	T808N	Neutral	0.06
NPC1	O15118-1.2	T808P	Neutral	0.097
NPC1	O15118-1.2	T808Q	Neutral	0.106
NPC1	O15118-1.2	T808R	Neutral	0.101
NPC1	O15118-1.2	T808S	Neutral	0.055
NPC1	O15118-1.2	T808V	Neutral	0.061
NPC1	O15118-1.2	T808W	Neutral	0.124
NPC1	O15118-1.2	T808Y	Neutral	0.16
NPC1	O15118-1.2	S809A	Neutral	0.09
NPC1	O15118-1.2	S809C	Neutral	0.151
NPC1	O15118-1.2	S809D	Neutral	0.121
NPC1	O15118-1.2	S809E	Neutral	0.138
NPC1	O15118-1.2	S809F	Neutral	0.212
NPC1	O15118-1.2	S809G	Neutral	0.153
NPC1	O15118-1.2	S809H	Neutral	0.223
NPC1	O15118-1.2	S809I	Neutral	0.201
NPC1	O15118-1.2	S809K	Neutral	0.143
NPC1	O15118-1.2	S809L	Neutral	0.206
NPC1	O15118-1.2	S809M	Neutral	0.171
NPC1	O15118-1.2	S809N	Neutral	0.092
NPC1	O15118-1.2	S809P	Neutral	0.166
NPC1	O15118-1.2	S809Q	Neutral	0.159
NPC1	O15118-1.2	S809R	Neutral	0.209
NPC1	O15118-1.2	S809T	Neutral	0.099
NPC1	O15118-1.2	S809V	Neutral	0.214
NPC1	O15118-1.2	S809W	Neutral	0.287
NPC1	O15118-1.2	S809Y	Neutral	0.269
NPC1	O15118-1.2	V810A	Neutral	0.17
NPC1	O15118-1.2	V810C	Neutral	0.252
NPC1	O15118-1.2	V810D	Neutral	0.283
NPC1	O15118-1.2	V810E	Neutral	0.209
NPC1	O15118-1.2	V810F	Neutral	0.243
NPC1	O15118-1.2	V810G	Neutral	0.398
NPC1	O15118-1.2	V810H	Neutral	0.346
NPC1	O15118-1.2	V810I	Neutral	0.06
NPC1	O15118-1.2	V810K	Neutral	0.215
NPC1	O15118-1.2	V810L	Neutral	0.125
NPC1	O15118-1.2	V810M	Neutral	0.143
NPC1	O15118-1.2	V810N	Neutral	0.288
NPC1	O15118-1.2	V810P	Neutral	0.307
NPC1	O15118-1.2	V810Q	Neutral	0.238
NPC1	O15118-1.2	V810R	Neutral	0.303
NPC1	O15118-1.2	V810S	Neutral	0.276
NPC1	O15118-1.2	V810T	Neutral	0.147
NPC1	O15118-1.2	V810W	Neutral	0.414
NPC1	O15118-1.2	V810Y	Neutral	0.27
NPC1	O15118-1.2	Q811A	Neutral	0.342
NPC1	O15118-1.2	Q811C	Neutral	0.444
NPC1	O15118-1.2	Q811D	Neutral	0.232
NPC1	O15118-1.2	Q811E	Neutral	0.116
NPC1	O15118-1.2	Q811F	Neutral	0.37
NPC1	O15118-1.2	Q811G	Neutral	0.487
NPC1	O15118-1.2	Q811H	Neutral	0.224
NPC1	O15118-1.2	Q811I	Neutral	0.353
NPC1	O15118-1.2	Q811K	Neutral	0.159
NPC1	O15118-1.2	Q811L	Neutral	0.277
NPC1	O15118-1.2	Q811M	Neutral	0.172
NPC1	O15118-1.2	Q811N	Neutral	0.237
NPC1	O15118-1.2	Q811P	Neutral	0.283
NPC1	O15118-1.2	Q811R	Neutral	0.169
NPC1	O15118-1.2	Q811S	Neutral	0.276
NPC1	O15118-1.2	Q811T	Neutral	0.311
NPC1	O15118-1.2	Q811V	Neutral	0.31
NPC1	O15118-1.2	Q811W	Neutral	0.288
NPC1	O15118-1.2	Q811Y	Neutral	0.27
NPC1	O15118-1.2	A812C	Neutral	0.115
NPC1	O15118-1.2	A812D	Neutral	0.202
NPC1	O15118-1.2	A812E	Neutral	0.167
NPC1	O15118-1.2	A812F	Neutral	0.224
NPC1	O15118-1.2	A812G	Neutral	0.128
NPC1	O15118-1.2	A812H	Neutral	0.287
NPC1	O15118-1.2	A812I	Neutral	0.155
NPC1	O15118-1.2	A812K	Neutral	0.173
NPC1	O15118-1.2	A812L	Neutral	0.159
NPC1	O15118-1.2	A812M	Neutral	0.181
NPC1	O15118-1.2	A812N	Neutral	0.216
NPC1	O15118-1.2	A812P	Neutral	0.176
NPC1	O15118-1.2	A812Q	Neutral	0.192
NPC1	O15118-1.2	A812R	Neutral	0.184
NPC1	O15118-1.2	A812S	Neutral	0.083
NPC1	O15118-1.2	A812T	Neutral	0.143
NPC1	O15118-1.2	A812V	Neutral	0.119
NPC1	O15118-1.2	A812W	Neutral	0.302
NPC1	O15118-1.2	A812Y	Neutral	0.283
NPC1	O15118-1.2	S813A	Neutral	0.188
NPC1	O15118-1.2	S813C	Neutral	0.295
NPC1	O15118-1.2	S813D	Neutral	0.244
NPC1	O15118-1.2	S813E	Neutral	0.273
NPC1	O15118-1.2	S813F	Neutral	0.388
NPC1	O15118-1.2	S813G	Neutral	0.298
NPC1	O15118-1.2	S813H	Neutral	0.402
NPC1	O15118-1.2	S813I	Neutral	0.371
NPC1	O15118-1.2	S813K	Neutral	0.281
NPC1	O15118-1.2	S813L	Neutral	0.379
NPC1	O15118-1.2	S813M	Neutral	0.326
NPC1	O15118-1.2	S813N	Neutral	0.193
NPC1	O15118-1.2	S813P	Neutral	0.319
NPC1	O15118-1.2	S813Q	Neutral	0.308
NPC1	O15118-1.2	S813R	Neutral	0.382
NPC1	O15118-1.2	S813T	Neutral	0.204
NPC1	O15118-1.2	S813V	Neutral	0.39
NPC1	O15118-1.2	S813W	Neutral	0.486
NPC1	O15118-1.2	S813Y	Neutral	0.464
NPC1	O15118-1.2	E814A	Pathogenic	0.635
NPC1	O15118-1.2	E814C	Pathogenic	0.798
NPC1	O15118-1.2	E814D	Neutral	0.382
NPC1	O15118-1.2	E814F	Pathogenic	0.676
NPC1	O15118-1.2	E814G	Pathogenic	0.761
NPC1	O15118-1.2	E814H	Pathogenic	0.506
NPC1	O15118-1.2	E814I	Pathogenic	0.66
NPC1	O15118-1.2	E814K	Neutral	0.47
NPC1	O15118-1.2	E814L	Pathogenic	0.668
NPC1	O15118-1.2	E814M	Pathogenic	0.615
NPC1	O15118-1.2	E814N	Pathogenic	0.573
NPC1	O15118-1.2	E814P	Pathogenic	0.569
NPC1	O15118-1.2	E814Q	Neutral	0.342
NPC1	O15118-1.2	E814R	Pathogenic	0.585
NPC1	O15118-1.2	E814S	Pathogenic	0.561
NPC1	O15118-1.2	E814T	Pathogenic	0.602
NPC1	O15118-1.2	E814V	Pathogenic	0.6
NPC1	O15118-1.2	E814W	Pathogenic	0.679
NPC1	O15118-1.2	E814Y	Pathogenic	0.66
NPC1	O15118-1.2	S815A	Pathogenic	0.569
NPC1	O15118-1.2	S815C	Pathogenic	0.704
NPC1	O15118-1.2	S815D	Pathogenic	0.647
NPC1	O15118-1.2	S815E	Pathogenic	0.681
NPC1	O15118-1.2	S815F	Pathogenic	0.783
NPC1	O15118-1.2	S815G	Pathogenic	0.707
NPC1	O15118-1.2	S815H	Pathogenic	0.793
NPC1	O15118-1.2	S815I	Pathogenic	0.77
NPC1	O15118-1.2	S815K	Pathogenic	0.69
NPC1	O15118-1.2	S815L	Pathogenic	0.776
NPC1	O15118-1.2	S815M	Pathogenic	0.734
NPC1	O15118-1.2	S815N	Pathogenic	0.576
NPC1	O15118-1.2	S815P	Pathogenic	0.727
NPC1	O15118-1.2	S815Q	Pathogenic	0.717
NPC1	O15118-1.2	S815R	Pathogenic	0.779
NPC1	O15118-1.2	S815T	Pathogenic	0.593
NPC1	O15118-1.2	S815V	Pathogenic	0.784
NPC1	O15118-1.2	S815W	Pathogenic	0.843
NPC1	O15118-1.2	S815Y	Pathogenic	0.831
NPC1	O15118-1.2	C816A	Neutral	0.215
NPC1	O15118-1.2	C816D	Neutral	0.359
NPC1	O15118-1.2	C816E	Neutral	0.489
NPC1	O15118-1.2	C816F	Neutral	0.405
NPC1	O15118-1.2	C816G	Neutral	0.469
NPC1	O15118-1.2	C816H	Neutral	0.47
NPC1	O15118-1.2	C816I	Neutral	0.301
NPC1	O15118-1.2	C816K	Neutral	0.404
NPC1	O15118-1.2	C816L	Neutral	0.308
NPC1	O15118-1.2	C816M	Neutral	0.342
NPC1	O15118-1.2	C816N	Neutral	0.379
NPC1	O15118-1.2	C816P	Neutral	0.477
NPC1	O15118-1.2	C816Q	Neutral	0.435
NPC1	O15118-1.2	C816R	Neutral	0.422
NPC1	O15118-1.2	C816S	Neutral	0.257
NPC1	O15118-1.2	C816T	Neutral	0.269
NPC1	O15118-1.2	C816V	Neutral	0.318
NPC1	O15118-1.2	C816W	Neutral	0.408
NPC1	O15118-1.2	C816Y	Neutral	0.478
NPC1	O15118-1.2	L817A	Pathogenic	0.925
NPC1	O15118-1.2	L817C	Pathogenic	0.933
NPC1	O15118-1.2	L817D	Pathogenic	0.96
NPC1	O15118-1.2	L817E	Pathogenic	0.938
NPC1	O15118-1.2	L817F	Pathogenic	0.908
NPC1	O15118-1.2	L817G	Pathogenic	0.976
NPC1	O15118-1.2	L817H	Pathogenic	0.949
NPC1	O15118-1.2	L817I	Pathogenic	0.809
NPC1	O15118-1.2	L817K	Pathogenic	0.9
NPC1	O15118-1.2	L817M	Pathogenic	0.79
NPC1	O15118-1.2	L817N	Pathogenic	0.943
NPC1	O15118-1.2	L817P	Pathogenic	0.964
NPC1	O15118-1.2	L817Q	Pathogenic	0.92
NPC1	O15118-1.2	L817R	Pathogenic	0.906
NPC1	O15118-1.2	L817S	Pathogenic	0.94
NPC1	O15118-1.2	L817T	Pathogenic	0.913
NPC1	O15118-1.2	L817V	Pathogenic	0.861
NPC1	O15118-1.2	L817W	Pathogenic	0.956
NPC1	O15118-1.2	L817Y	Pathogenic	0.924
NPC1	O15118-1.2	F818A	Pathogenic	0.757
NPC1	O15118-1.2	F818C	Pathogenic	0.777
NPC1	O15118-1.2	F818D	Pathogenic	0.735
NPC1	O15118-1.2	F818E	Pathogenic	0.722
NPC1	O15118-1.2	F818G	Pathogenic	0.823
NPC1	O15118-1.2	F818H	Pathogenic	0.595
NPC1	O15118-1.2	F818I	Pathogenic	0.624
NPC1	O15118-1.2	F818K	Pathogenic	0.664
NPC1	O15118-1.2	F818L	Pathogenic	0.618
NPC1	O15118-1.2	F818M	Pathogenic	0.581
NPC1	O15118-1.2	F818N	Pathogenic	0.74
NPC1	O15118-1.2	F818P	Pathogenic	0.871
NPC1	O15118-1.2	F818Q	Pathogenic	0.743
NPC1	O15118-1.2	F818R	Pathogenic	0.68
NPC1	O15118-1.2	F818S	Pathogenic	0.728
NPC1	O15118-1.2	F818T	Pathogenic	0.724
NPC1	O15118-1.2	F818V	Pathogenic	0.695
NPC1	O15118-1.2	F818W	Pathogenic	0.519
NPC1	O15118-1.2	F818Y	Neutral	0.279
NPC1	O15118-1.2	R819A	Neutral	0.396
NPC1	O15118-1.2	R819C	Pathogenic	0.503
NPC1	O15118-1.2	R819D	Pathogenic	0.544
NPC1	O15118-1.2	R819E	Neutral	0.322
NPC1	O15118-1.2	R819F	Neutral	0.365
NPC1	O15118-1.2	R819G	Pathogenic	0.546
NPC1	O15118-1.2	R819H	Neutral	0.258
NPC1	O15118-1.2	R819I	Neutral	0.38
NPC1	O15118-1.2	R819K	Neutral	0.174
NPC1	O15118-1.2	R819L	Neutral	0.301
NPC1	O15118-1.2	R819M	Neutral	0.255
NPC1	O15118-1.2	R819N	Neutral	0.336
NPC1	O15118-1.2	R819P	Neutral	0.423
NPC1	O15118-1.2	R819Q	Neutral	0.214
NPC1	O15118-1.2	R819S	Neutral	0.415
NPC1	O15118-1.2	R819T	Neutral	0.363
NPC1	O15118-1.2	R819V	Neutral	0.455
NPC1	O15118-1.2	R819W	Neutral	0.333
NPC1	O15118-1.2	R819Y	Neutral	0.332
NPC1	O15118-1.2	F820A	Pathogenic	0.802
NPC1	O15118-1.2	F820C	Pathogenic	0.819
NPC1	O15118-1.2	F820D	Pathogenic	0.783
NPC1	O15118-1.2	F820E	Pathogenic	0.771
NPC1	O15118-1.2	F820G	Pathogenic	0.858
NPC1	O15118-1.2	F820H	Pathogenic	0.656
NPC1	O15118-1.2	F820I	Pathogenic	0.684
NPC1	O15118-1.2	F820K	Pathogenic	0.72
NPC1	O15118-1.2	F820L	Pathogenic	0.678
NPC1	O15118-1.2	F820M	Pathogenic	0.643
NPC1	O15118-1.2	F820N	Pathogenic	0.787
NPC1	O15118-1.2	F820P	Pathogenic	0.897
NPC1	O15118-1.2	F820Q	Pathogenic	0.79
NPC1	O15118-1.2	F820R	Pathogenic	0.734
NPC1	O15118-1.2	F820S	Pathogenic	0.777
NPC1	O15118-1.2	F820T	Pathogenic	0.773
NPC1	O15118-1.2	F820V	Pathogenic	0.748
NPC1	O15118-1.2	F820W	Pathogenic	0.584
NPC1	O15118-1.2	F820Y	Neutral	0.334
NPC1	O15118-1.2	F821A	Pathogenic	0.859
NPC1	O15118-1.2	F821C	Pathogenic	0.872
NPC1	O15118-1.2	F821D	Pathogenic	0.845
NPC1	O15118-1.2	F821E	Pathogenic	0.836
NPC1	O15118-1.2	F821G	Pathogenic	0.901
NPC1	O15118-1.2	F821H	Pathogenic	0.742
NPC1	O15118-1.2	F821I	Pathogenic	0.765
NPC1	O15118-1.2	F821K	Pathogenic	0.795
NPC1	O15118-1.2	F821L	Pathogenic	0.761
NPC1	O15118-1.2	F821M	Pathogenic	0.731
NPC1	O15118-1.2	F821N	Pathogenic	0.848
NPC1	O15118-1.2	F821P	Pathogenic	0.93
NPC1	O15118-1.2	F821Q	Pathogenic	0.85
NPC1	O15118-1.2	F821R	Pathogenic	0.807
NPC1	O15118-1.2	F821S	Pathogenic	0.84
NPC1	O15118-1.2	F821T	Pathogenic	0.837
NPC1	O15118-1.2	F821V	Pathogenic	0.817
NPC1	O15118-1.2	F821W	Pathogenic	0.679
NPC1	O15118-1.2	F821Y	Neutral	0.431
NPC1	O15118-1.2	K822A	Pathogenic	0.838
NPC1	O15118-1.2	K822C	Pathogenic	0.888
NPC1	O15118-1.2	K822D	Pathogenic	0.865
NPC1	O15118-1.2	K822E	Pathogenic	0.717
NPC1	O15118-1.2	K822F	Pathogenic	0.819
NPC1	O15118-1.2	K822G	Pathogenic	0.904
NPC1	O15118-1.2	K822H	Pathogenic	0.801
NPC1	O15118-1.2	K822I	Pathogenic	0.828
NPC1	O15118-1.2	K822L	Pathogenic	0.772
NPC1	O15118-1.2	K822M	Pathogenic	0.729
NPC1	O15118-1.2	K822N	Pathogenic	0.799
NPC1	O15118-1.2	K822P	Pathogenic	0.797
NPC1	O15118-1.2	K822Q	Pathogenic	0.682
NPC1	O15118-1.2	K822R	Pathogenic	0.641
NPC1	O15118-1.2	K822S	Pathogenic	0.792
NPC1	O15118-1.2	K822T	Pathogenic	0.818
NPC1	O15118-1.2	K822V	Pathogenic	0.817
NPC1	O15118-1.2	K822W	Pathogenic	0.821
NPC1	O15118-1.2	K822Y	Pathogenic	0.808
NPC1	O15118-1.2	N823A	Pathogenic	0.515
NPC1	O15118-1.2	N823C	Pathogenic	0.526
NPC1	O15118-1.2	N823D	Neutral	0.269
NPC1	O15118-1.2	N823E	Neutral	0.373
NPC1	O15118-1.2	N823F	Pathogenic	0.503
NPC1	O15118-1.2	N823G	Neutral	0.379
NPC1	O15118-1.2	N823H	Neutral	0.253
NPC1	O15118-1.2	N823I	Neutral	0.485
NPC1	O15118-1.2	N823K	Neutral	0.382
NPC1	O15118-1.2	N823L	Neutral	0.494
NPC1	O15118-1.2	N823M	Neutral	0.437
NPC1	O15118-1.2	N823P	Neutral	0.446
NPC1	O15118-1.2	N823Q	Neutral	0.354
NPC1	O15118-1.2	N823R	Neutral	0.4
NPC1	O15118-1.2	N823S	Neutral	0.265
NPC1	O15118-1.2	N823T	Neutral	0.299
NPC1	O15118-1.2	N823V	Pathogenic	0.505
NPC1	O15118-1.2	N823W	Pathogenic	0.602
NPC1	O15118-1.2	N823Y	Neutral	0.485
NPC1	O15118-1.2	S824A	Neutral	0.113
NPC1	O15118-1.2	S824C	Neutral	0.187
NPC1	O15118-1.2	S824D	Neutral	0.15
NPC1	O15118-1.2	S824E	Neutral	0.171
NPC1	O15118-1.2	S824F	Neutral	0.258
NPC1	O15118-1.2	S824G	Neutral	0.189
NPC1	O15118-1.2	S824H	Neutral	0.27
NPC1	O15118-1.2	S824I	Neutral	0.244
NPC1	O15118-1.2	S824K	Neutral	0.177
NPC1	O15118-1.2	S824L	Neutral	0.251
NPC1	O15118-1.2	S824M	Neutral	0.21
NPC1	O15118-1.2	S824N	Neutral	0.116
NPC1	O15118-1.2	S824P	Neutral	0.204
NPC1	O15118-1.2	S824Q	Neutral	0.196
NPC1	O15118-1.2	S824R	Neutral	0.253
NPC1	O15118-1.2	S824T	Neutral	0.123
NPC1	O15118-1.2	S824V	Neutral	0.259
NPC1	O15118-1.2	S824W	Neutral	0.342
NPC1	O15118-1.2	S824Y	Neutral	0.322
NPC1	O15118-1.2	Y825A	Pathogenic	0.954
NPC1	O15118-1.2	Y825C	Pathogenic	0.958
NPC1	O15118-1.2	Y825D	Pathogenic	0.949
NPC1	O15118-1.2	Y825E	Pathogenic	0.922
NPC1	O15118-1.2	Y825F	Pathogenic	0.655
NPC1	O15118-1.2	Y825G	Pathogenic	0.969
NPC1	O15118-1.2	Y825H	Pathogenic	0.756
NPC1	O15118-1.2	Y825I	Pathogenic	0.904
NPC1	O15118-1.2	Y825K	Pathogenic	0.9
NPC1	O15118-1.2	Y825L	Pathogenic	0.907
NPC1	O15118-1.2	Y825M	Pathogenic	0.92
NPC1	O15118-1.2	Y825N	Pathogenic	0.928
NPC1	O15118-1.2	Y825P	Pathogenic	0.968
NPC1	O15118-1.2	Y825Q	Pathogenic	0.9
NPC1	O15118-1.2	Y825R	Pathogenic	0.9
NPC1	O15118-1.2	Y825S	Pathogenic	0.947
NPC1	O15118-1.2	Y825T	Pathogenic	0.946
NPC1	O15118-1.2	Y825V	Pathogenic	0.928
NPC1	O15118-1.2	Y825W	Pathogenic	0.725
NPC1	O15118-1.2	S826A	Neutral	0.388
NPC1	O15118-1.2	S826C	Pathogenic	0.533
NPC1	O15118-1.2	S826D	Neutral	0.468
NPC1	O15118-1.2	S826E	Pathogenic	0.506
NPC1	O15118-1.2	S826F	Pathogenic	0.633
NPC1	O15118-1.2	S826G	Pathogenic	0.536
NPC1	O15118-1.2	S826H	Pathogenic	0.648
NPC1	O15118-1.2	S826I	Pathogenic	0.617
NPC1	O15118-1.2	S826K	Pathogenic	0.516
NPC1	O15118-1.2	S826L	Pathogenic	0.625
NPC1	O15118-1.2	S826M	Pathogenic	0.569
NPC1	O15118-1.2	S826N	Neutral	0.395
NPC1	O15118-1.2	S826P	Pathogenic	0.561
NPC1	O15118-1.2	S826Q	Pathogenic	0.548
NPC1	O15118-1.2	S826R	Pathogenic	0.628
NPC1	O15118-1.2	S826T	Neutral	0.412
NPC1	O15118-1.2	S826V	Pathogenic	0.635
NPC1	O15118-1.2	S826W	Pathogenic	0.721
NPC1	O15118-1.2	S826Y	Pathogenic	0.702
NPC1	O15118-1.2	P827A	Pathogenic	0.948
NPC1	O15118-1.2	P827C	Pathogenic	0.973
NPC1	O15118-1.2	P827D	Pathogenic	0.917
NPC1	O15118-1.2	P827E	Pathogenic	0.928
NPC1	O15118-1.2	P827F	Pathogenic	0.981
NPC1	O15118-1.2	P827G	Pathogenic	0.964
NPC1	O15118-1.2	P827H	Pathogenic	0.963
NPC1	O15118-1.2	P827I	Pathogenic	0.971
NPC1	O15118-1.2	P827K	Pathogenic	0.931
NPC1	O15118-1.2	P827L	Pathogenic	0.972
NPC1	O15118-1.2	P827M	Pathogenic	0.965
NPC1	O15118-1.2	P827N	Pathogenic	0.947
NPC1	O15118-1.2	P827Q	Pathogenic	0.939
NPC1	O15118-1.2	P827R	Pathogenic	0.955
NPC1	O15118-1.2	P827S	Pathogenic	0.94
NPC1	O15118-1.2	P827T	Pathogenic	0.94
NPC1	O15118-1.2	P827V	Pathogenic	0.961
NPC1	O15118-1.2	P827W	Pathogenic	0.982
NPC1	O15118-1.2	P827Y	Pathogenic	0.98
NPC1	O15118-1.2	L828A	Neutral	0.39
NPC1	O15118-1.2	L828C	Neutral	0.416
NPC1	O15118-1.2	L828D	Pathogenic	0.551
NPC1	O15118-1.2	L828E	Neutral	0.439
NPC1	O15118-1.2	L828F	Neutral	0.336
NPC1	O15118-1.2	L828G	Pathogenic	0.673
NPC1	O15118-1.2	L828H	Neutral	0.489
NPC1	O15118-1.2	L828I	Neutral	0.179
NPC1	O15118-1.2	L828K	Neutral	0.316
NPC1	O15118-1.2	L828M	Neutral	0.162
NPC1	O15118-1.2	L828N	Neutral	0.461
NPC1	O15118-1.2	L828P	Pathogenic	0.579
NPC1	O15118-1.2	L828Q	Neutral	0.372
NPC1	O15118-1.2	L828R	Neutral	0.332
NPC1	O15118-1.2	L828S	Neutral	0.447
NPC1	O15118-1.2	L828T	Neutral	0.349
NPC1	O15118-1.2	L828V	Neutral	0.241
NPC1	O15118-1.2	L828W	Pathogenic	0.527
NPC1	O15118-1.2	L828Y	Neutral	0.384
NPC1	O15118-1.2	L829A	Pathogenic	0.827
NPC1	O15118-1.2	L829C	Pathogenic	0.842
NPC1	O15118-1.2	L829D	Pathogenic	0.902
NPC1	O15118-1.2	L829E	Pathogenic	0.854
NPC1	O15118-1.2	L829F	Pathogenic	0.792
NPC1	O15118-1.2	L829G	Pathogenic	0.939
NPC1	O15118-1.2	L829H	Pathogenic	0.878
NPC1	O15118-1.2	L829I	Pathogenic	0.621
NPC1	O15118-1.2	L829K	Pathogenic	0.776
NPC1	O15118-1.2	L829M	Pathogenic	0.592
NPC1	O15118-1.2	L829N	Pathogenic	0.865
NPC1	O15118-1.2	L829P	Pathogenic	0.912
NPC1	O15118-1.2	L829Q	Pathogenic	0.816
NPC1	O15118-1.2	L829R	Pathogenic	0.788
NPC1	O15118-1.2	L829S	Pathogenic	0.858
NPC1	O15118-1.2	L829T	Pathogenic	0.801
NPC1	O15118-1.2	L829V	Pathogenic	0.704
NPC1	O15118-1.2	L829W	Pathogenic	0.893
NPC1	O15118-1.2	L829Y	Pathogenic	0.824
NPC1	O15118-1.2	L830A	Pathogenic	0.829
NPC1	O15118-1.2	L830C	Pathogenic	0.844
NPC1	O15118-1.2	L830D	Pathogenic	0.903
NPC1	O15118-1.2	L830E	Pathogenic	0.856
NPC1	O15118-1.2	L830F	Pathogenic	0.794
NPC1	O15118-1.2	L830G	Pathogenic	0.94
NPC1	O15118-1.2	L830H	Pathogenic	0.879
NPC1	O15118-1.2	L830I	Pathogenic	0.624
NPC1	O15118-1.2	L830K	Pathogenic	0.778
NPC1	O15118-1.2	L830M	Pathogenic	0.595
NPC1	O15118-1.2	L830N	Pathogenic	0.867
NPC1	O15118-1.2	L830P	Pathogenic	0.913
NPC1	O15118-1.2	L830Q	Pathogenic	0.819
NPC1	O15118-1.2	L830R	Pathogenic	0.791
NPC1	O15118-1.2	L830S	Pathogenic	0.86
NPC1	O15118-1.2	L830T	Pathogenic	0.803
NPC1	O15118-1.2	L830V	Pathogenic	0.707
NPC1	O15118-1.2	L830W	Pathogenic	0.895
NPC1	O15118-1.2	L830Y	Pathogenic	0.826
NPC1	O15118-1.2	K831A	Pathogenic	0.688
NPC1	O15118-1.2	K831C	Pathogenic	0.772
NPC1	O15118-1.2	K831D	Pathogenic	0.732
NPC1	O15118-1.2	K831E	Pathogenic	0.52
NPC1	O15118-1.2	K831F	Pathogenic	0.659
NPC1	O15118-1.2	K831G	Pathogenic	0.801
NPC1	O15118-1.2	K831H	Pathogenic	0.632
NPC1	O15118-1.2	K831I	Pathogenic	0.672
NPC1	O15118-1.2	K831L	Pathogenic	0.591
NPC1	O15118-1.2	K831M	Pathogenic	0.534
NPC1	O15118-1.2	K831N	Pathogenic	0.63
NPC1	O15118-1.2	K831P	Pathogenic	0.626
NPC1	O15118-1.2	K831Q	Neutral	0.477
NPC1	O15118-1.2	K831R	Neutral	0.432
NPC1	O15118-1.2	K831S	Pathogenic	0.618
NPC1	O15118-1.2	K831T	Pathogenic	0.657
NPC1	O15118-1.2	K831V	Pathogenic	0.656
NPC1	O15118-1.2	K831W	Pathogenic	0.662
NPC1	O15118-1.2	K831Y	Pathogenic	0.642
NPC1	O15118-1.2	D832A	Pathogenic	0.534
NPC1	O15118-1.2	D832C	Pathogenic	0.546
NPC1	O15118-1.2	D832E	Neutral	0.244
NPC1	O15118-1.2	D832F	Pathogenic	0.538
NPC1	O15118-1.2	D832G	Neutral	0.492
NPC1	O15118-1.2	D832H	Neutral	0.457
NPC1	O15118-1.2	D832I	Pathogenic	0.52
NPC1	O15118-1.2	D832K	Pathogenic	0.539
NPC1	O15118-1.2	D832L	Pathogenic	0.622
NPC1	O15118-1.2	D832M	Pathogenic	0.567
NPC1	O15118-1.2	D832N	Neutral	0.303
NPC1	O15118-1.2	D832P	Neutral	0.372
NPC1	O15118-1.2	D832Q	Neutral	0.386
NPC1	O15118-1.2	D832R	Pathogenic	0.649
NPC1	O15118-1.2	D832S	Neutral	0.364
NPC1	O15118-1.2	D832T	Neutral	0.41
NPC1	O15118-1.2	D832V	Pathogenic	0.54
NPC1	O15118-1.2	D832W	Pathogenic	0.635
NPC1	O15118-1.2	D832Y	Pathogenic	0.614
NPC1	O15118-1.2	W833A	Pathogenic	0.527
NPC1	O15118-1.2	W833C	Neutral	0.458
NPC1	O15118-1.2	W833D	Neutral	0.498
NPC1	O15118-1.2	W833E	Neutral	0.387
NPC1	O15118-1.2	W833F	Neutral	0.205
NPC1	O15118-1.2	W833G	Neutral	0.434
NPC1	O15118-1.2	W833H	Neutral	0.344
NPC1	O15118-1.2	W833I	Pathogenic	0.565
NPC1	O15118-1.2	W833K	Neutral	0.324
NPC1	O15118-1.2	W833L	Neutral	0.46
NPC1	O15118-1.2	W833M	Neutral	0.332
NPC1	O15118-1.2	W833N	Pathogenic	0.504
NPC1	O15118-1.2	W833P	Pathogenic	0.621
NPC1	O15118-1.2	W833Q	Neutral	0.324
NPC1	O15118-1.2	W833R	Neutral	0.306
NPC1	O15118-1.2	W833S	Neutral	0.49
NPC1	O15118-1.2	W833T	Neutral	0.389
NPC1	O15118-1.2	W833V	Pathogenic	0.545
NPC1	O15118-1.2	W833Y	Neutral	0.114
NPC1	O15118-1.2	M834A	Neutral	0.333
NPC1	O15118-1.2	M834C	Neutral	0.358
NPC1	O15118-1.2	M834D	Neutral	0.396
NPC1	O15118-1.2	M834E	Neutral	0.294
NPC1	O15118-1.2	M834F	Neutral	0.225
NPC1	O15118-1.2	M834G	Pathogenic	0.523
NPC1	O15118-1.2	M834H	Neutral	0.338
NPC1	O15118-1.2	M834I	Neutral	0.156
NPC1	O15118-1.2	M834K	Neutral	0.198
NPC1	O15118-1.2	M834L	Neutral	0.115
NPC1	O15118-1.2	M834N	Neutral	0.313
NPC1	O15118-1.2	M834P	Neutral	0.423
NPC1	O15118-1.2	M834Q	Neutral	0.177
NPC1	O15118-1.2	M834R	Neutral	0.209
NPC1	O15118-1.2	M834S	Neutral	0.301
NPC1	O15118-1.2	M834T	Neutral	0.296
NPC1	O15118-1.2	M834V	Neutral	0.199
NPC1	O15118-1.2	M834W	Neutral	0.303
NPC1	O15118-1.2	M834Y	Neutral	0.328
NPC1	O15118-1.2	R835A	Pathogenic	0.87
NPC1	O15118-1.2	R835C	Pathogenic	0.912
NPC1	O15118-1.2	R835D	Pathogenic	0.924
NPC1	O15118-1.2	R835E	Pathogenic	0.829
NPC1	O15118-1.2	R835F	Pathogenic	0.855
NPC1	O15118-1.2	R835G	Pathogenic	0.925
NPC1	O15118-1.2	R835H	Pathogenic	0.78
NPC1	O15118-1.2	R835I	Pathogenic	0.862
NPC1	O15118-1.2	R835K	Pathogenic	0.683
NPC1	O15118-1.2	R835L	Pathogenic	0.815
NPC1	O15118-1.2	R835M	Pathogenic	0.778
NPC1	O15118-1.2	R835N	Pathogenic	0.838
NPC1	O15118-1.2	R835P	Pathogenic	0.882
NPC1	O15118-1.2	R835Q	Pathogenic	0.735
NPC1	O15118-1.2	R835S	Pathogenic	0.879
NPC1	O15118-1.2	R835T	Pathogenic	0.854
NPC1	O15118-1.2	R835V	Pathogenic	0.895
NPC1	O15118-1.2	R835W	Pathogenic	0.836
NPC1	O15118-1.2	R835Y	Pathogenic	0.835
NPC1	O15118-1.2	P836A	Neutral	0.368
NPC1	O15118-1.2	P836C	Pathogenic	0.541
NPC1	O15118-1.2	P836D	Neutral	0.262
NPC1	O15118-1.2	P836E	Neutral	0.293
NPC1	O15118-1.2	P836F	Pathogenic	0.629
NPC1	O15118-1.2	P836G	Neutral	0.464
NPC1	O15118-1.2	P836H	Neutral	0.454
NPC1	O15118-1.2	P836I	Pathogenic	0.518
NPC1	O15118-1.2	P836K	Neutral	0.301
NPC1	O15118-1.2	P836L	Pathogenic	0.526
NPC1	O15118-1.2	P836M	Neutral	0.469
NPC1	O15118-1.2	P836N	Neutral	0.363
NPC1	O15118-1.2	P836Q	Neutral	0.329
NPC1	O15118-1.2	P836R	Neutral	0.406
NPC1	O15118-1.2	P836S	Neutral	0.333
NPC1	O15118-1.2	P836T	Neutral	0.336
NPC1	O15118-1.2	P836V	Neutral	0.442
NPC1	O15118-1.2	P836W	Pathogenic	0.633
NPC1	O15118-1.2	P836Y	Pathogenic	0.612
NPC1	O15118-1.2	I837A	Neutral	0.16
NPC1	O15118-1.2	I837C	Neutral	0.175
NPC1	O15118-1.2	I837D	Neutral	0.199
NPC1	O15118-1.2	I837E	Neutral	0.189
NPC1	O15118-1.2	I837F	Neutral	0.138
NPC1	O15118-1.2	I837G	Neutral	0.38
NPC1	O15118-1.2	I837H	Neutral	0.222
NPC1	O15118-1.2	I837K	Neutral	0.168
NPC1	O15118-1.2	I837L	Neutral	0.063
NPC1	O15118-1.2	I837M	Neutral	0.078
NPC1	O15118-1.2	I837N	Neutral	0.203
NPC1	O15118-1.2	I837P	Neutral	0.291
NPC1	O15118-1.2	I837Q	Neutral	0.206
NPC1	O15118-1.2	I837R	Neutral	0.179
NPC1	O15118-1.2	I837S	Neutral	0.194
NPC1	O15118-1.2	I837T	Neutral	0.138
NPC1	O15118-1.2	I837V	Neutral	0.042
NPC1	O15118-1.2	I837W	Neutral	0.343
NPC1	O15118-1.2	I837Y	Neutral	0.156
NPC1	O15118-1.2	V838A	Pathogenic	0.586
NPC1	O15118-1.2	V838C	Pathogenic	0.699
NPC1	O15118-1.2	V838D	Pathogenic	0.731
NPC1	O15118-1.2	V838E	Pathogenic	0.645
NPC1	O15118-1.2	V838F	Pathogenic	0.689
NPC1	O15118-1.2	V838G	Pathogenic	0.82
NPC1	O15118-1.2	V838H	Pathogenic	0.785
NPC1	O15118-1.2	V838I	Neutral	0.306
NPC1	O15118-1.2	V838K	Pathogenic	0.654
NPC1	O15118-1.2	V838L	Neutral	0.497
NPC1	O15118-1.2	V838M	Pathogenic	0.536
NPC1	O15118-1.2	V838N	Pathogenic	0.736
NPC1	O15118-1.2	V838P	Pathogenic	0.753
NPC1	O15118-1.2	V838Q	Pathogenic	0.683
NPC1	O15118-1.2	V838R	Pathogenic	0.75
NPC1	O15118-1.2	V838S	Pathogenic	0.725
NPC1	O15118-1.2	V838T	Pathogenic	0.543
NPC1	O15118-1.2	V838W	Pathogenic	0.83
NPC1	O15118-1.2	V838Y	Pathogenic	0.718
NPC1	O15118-1.2	I839A	Neutral	0.294
NPC1	O15118-1.2	I839C	Neutral	0.317
NPC1	O15118-1.2	I839D	Neutral	0.353
NPC1	O15118-1.2	I839E	Neutral	0.338
NPC1	O15118-1.2	I839F	Neutral	0.26
NPC1	O15118-1.2	I839G	Pathogenic	0.573
NPC1	O15118-1.2	I839H	Neutral	0.384
NPC1	O15118-1.2	I839K	Neutral	0.307
NPC1	O15118-1.2	I839L	Neutral	0.128
NPC1	O15118-1.2	I839M	Neutral	0.156
NPC1	O15118-1.2	I839N	Neutral	0.358
NPC1	O15118-1.2	I839P	Neutral	0.473
NPC1	O15118-1.2	I839Q	Neutral	0.363
NPC1	O15118-1.2	I839R	Neutral	0.323
NPC1	O15118-1.2	I839S	Neutral	0.345
NPC1	O15118-1.2	I839T	Neutral	0.259
NPC1	O15118-1.2	I839V	Neutral	0.087
NPC1	O15118-1.2	I839W	Pathogenic	0.534
NPC1	O15118-1.2	I839Y	Neutral	0.289
NPC1	O15118-1.2	A840C	Neutral	0.133
NPC1	O15118-1.2	A840D	Neutral	0.23
NPC1	O15118-1.2	A840E	Neutral	0.191
NPC1	O15118-1.2	A840F	Neutral	0.254
NPC1	O15118-1.2	A840G	Neutral	0.147
NPC1	O15118-1.2	A840H	Neutral	0.322
NPC1	O15118-1.2	A840I	Neutral	0.177
NPC1	O15118-1.2	A840K	Neutral	0.197
NPC1	O15118-1.2	A840L	Neutral	0.182
NPC1	O15118-1.2	A840M	Neutral	0.207
NPC1	O15118-1.2	A840N	Neutral	0.245
NPC1	O15118-1.2	A840P	Neutral	0.201
NPC1	O15118-1.2	A840Q	Neutral	0.219
NPC1	O15118-1.2	A840R	Neutral	0.209
NPC1	O15118-1.2	A840S	Neutral	0.097
NPC1	O15118-1.2	A840T	Neutral	0.164
NPC1	O15118-1.2	A840V	Neutral	0.137
NPC1	O15118-1.2	A840W	Neutral	0.337
NPC1	O15118-1.2	A840Y	Neutral	0.317
NPC1	O15118-1.2	I841A	Neutral	0.201
NPC1	O15118-1.2	I841C	Neutral	0.219
NPC1	O15118-1.2	I841D	Neutral	0.247
NPC1	O15118-1.2	I841E	Neutral	0.235
NPC1	O15118-1.2	I841F	Neutral	0.175
NPC1	O15118-1.2	I841G	Neutral	0.447
NPC1	O15118-1.2	I841H	Neutral	0.273
NPC1	O15118-1.2	I841K	Neutral	0.211
NPC1	O15118-1.2	I841L	Neutral	0.082
NPC1	O15118-1.2	I841M	Neutral	0.101
NPC1	O15118-1.2	I841N	Neutral	0.252
NPC1	O15118-1.2	I841P	Neutral	0.351
NPC1	O15118-1.2	I841Q	Neutral	0.255
NPC1	O15118-1.2	I841R	Neutral	0.223
NPC1	O15118-1.2	I841S	Neutral	0.241
NPC1	O15118-1.2	I841T	Neutral	0.174
NPC1	O15118-1.2	I841V	Neutral	0.055
NPC1	O15118-1.2	I841W	Neutral	0.408
NPC1	O15118-1.2	I841Y	Neutral	0.197
NPC1	O15118-1.2	F842A	Pathogenic	0.874
NPC1	O15118-1.2	F842C	Pathogenic	0.886
NPC1	O15118-1.2	F842D	Pathogenic	0.861
NPC1	O15118-1.2	F842E	Pathogenic	0.853
NPC1	O15118-1.2	F842G	Pathogenic	0.912
NPC1	O15118-1.2	F842H	Pathogenic	0.766
NPC1	O15118-1.2	F842I	Pathogenic	0.788
NPC1	O15118-1.2	F842K	Pathogenic	0.815
NPC1	O15118-1.2	F842L	Pathogenic	0.784
NPC1	O15118-1.2	F842M	Pathogenic	0.756
NPC1	O15118-1.2	F842N	Pathogenic	0.864
NPC1	O15118-1.2	F842P	Pathogenic	0.938
NPC1	O15118-1.2	F842Q	Pathogenic	0.866
NPC1	O15118-1.2	F842R	Pathogenic	0.826
NPC1	O15118-1.2	F842S	Pathogenic	0.857
NPC1	O15118-1.2	F842T	Pathogenic	0.854
NPC1	O15118-1.2	F842V	Pathogenic	0.836
NPC1	O15118-1.2	F842W	Pathogenic	0.707
NPC1	O15118-1.2	F842Y	Neutral	0.463
NPC1	O15118-1.2	V843A	Neutral	0.233
NPC1	O15118-1.2	V843C	Neutral	0.333
NPC1	O15118-1.2	V843D	Neutral	0.369
NPC1	O15118-1.2	V843E	Neutral	0.281
NPC1	O15118-1.2	V843F	Neutral	0.323
NPC1	O15118-1.2	V843G	Neutral	0.495
NPC1	O15118-1.2	V843H	Neutral	0.44
NPC1	O15118-1.2	V843I	Neutral	0.087
NPC1	O15118-1.2	V843K	Neutral	0.289
NPC1	O15118-1.2	V843L	Neutral	0.175
NPC1	O15118-1.2	V843M	Neutral	0.199
NPC1	O15118-1.2	V843N	Neutral	0.375
NPC1	O15118-1.2	V843P	Neutral	0.396
NPC1	O15118-1.2	V843Q	Neutral	0.316
NPC1	O15118-1.2	V843R	Neutral	0.392
NPC1	O15118-1.2	V843S	Neutral	0.361
NPC1	O15118-1.2	V843T	Neutral	0.203
NPC1	O15118-1.2	V843W	Pathogenic	0.512
NPC1	O15118-1.2	V843Y	Neutral	0.354
NPC1	O15118-1.2	G844A	Neutral	0.494
NPC1	O15118-1.2	G844C	Pathogenic	0.736
NPC1	O15118-1.2	G844D	Pathogenic	0.588
NPC1	O15118-1.2	G844E	Pathogenic	0.709
NPC1	O15118-1.2	G844F	Pathogenic	0.741
NPC1	O15118-1.2	G844H	Pathogenic	0.753
NPC1	O15118-1.2	G844I	Pathogenic	0.797
NPC1	O15118-1.2	G844K	Pathogenic	0.718
NPC1	O15118-1.2	G844L	Pathogenic	0.802
NPC1	O15118-1.2	G844M	Pathogenic	0.764
NPC1	O15118-1.2	G844N	Pathogenic	0.514
NPC1	O15118-1.2	G844P	Pathogenic	0.679
NPC1	O15118-1.2	G844Q	Pathogenic	0.743
NPC1	O15118-1.2	G844R	Pathogenic	0.732
NPC1	O15118-1.2	G844S	Pathogenic	0.526
NPC1	O15118-1.2	G844T	Pathogenic	0.716
NPC1	O15118-1.2	G844V	Pathogenic	0.743
NPC1	O15118-1.2	G844W	Pathogenic	0.665
NPC1	O15118-1.2	G844Y	Pathogenic	0.797
NPC1	O15118-1.2	V845A	Neutral	0.096
NPC1	O15118-1.2	V845C	Neutral	0.149
NPC1	O15118-1.2	V845D	Neutral	0.17
NPC1	O15118-1.2	V845E	Neutral	0.12
NPC1	O15118-1.2	V845F	Neutral	0.143
NPC1	O15118-1.2	V845G	Neutral	0.255
NPC1	O15118-1.2	V845H	Neutral	0.215
NPC1	O15118-1.2	V845I	Neutral	0.032
NPC1	O15118-1.2	V845K	Neutral	0.125
NPC1	O15118-1.2	V845L	Neutral	0.069
NPC1	O15118-1.2	V845M	Neutral	0.08
NPC1	O15118-1.2	V845N	Neutral	0.173
NPC1	O15118-1.2	V845P	Neutral	0.187
NPC1	O15118-1.2	V845Q	Neutral	0.139
NPC1	O15118-1.2	V845R	Neutral	0.184
NPC1	O15118-1.2	V845S	Neutral	0.165
NPC1	O15118-1.2	V845T	Neutral	0.082
NPC1	O15118-1.2	V845W	Neutral	0.268
NPC1	O15118-1.2	V845Y	Neutral	0.161
NPC1	O15118-1.2	L846A	Neutral	0.395
NPC1	O15118-1.2	L846C	Neutral	0.421
NPC1	O15118-1.2	L846D	Pathogenic	0.557
NPC1	O15118-1.2	L846E	Neutral	0.444
NPC1	O15118-1.2	L846F	Neutral	0.341
NPC1	O15118-1.2	L846G	Pathogenic	0.678
NPC1	O15118-1.2	L846H	Neutral	0.495
NPC1	O15118-1.2	L846I	Neutral	0.182
NPC1	O15118-1.2	L846K	Neutral	0.321
NPC1	O15118-1.2	L846M	Neutral	0.165
NPC1	O15118-1.2	L846N	Neutral	0.467
NPC1	O15118-1.2	L846P	Pathogenic	0.585
NPC1	O15118-1.2	L846Q	Neutral	0.377
NPC1	O15118-1.2	L846R	Neutral	0.337
NPC1	O15118-1.2	L846S	Neutral	0.452
NPC1	O15118-1.2	L846T	Neutral	0.354
NPC1	O15118-1.2	L846V	Neutral	0.245
NPC1	O15118-1.2	L846W	Pathogenic	0.533
NPC1	O15118-1.2	L846Y	Neutral	0.389
NPC1	O15118-1.2	S847A	Neutral	0.235
NPC1	O15118-1.2	S847C	Neutral	0.357
NPC1	O15118-1.2	S847D	Neutral	0.299
NPC1	O15118-1.2	S847E	Neutral	0.332
NPC1	O15118-1.2	S847F	Neutral	0.456
NPC1	O15118-1.2	S847G	Neutral	0.36
NPC1	O15118-1.2	S847H	Neutral	0.471
NPC1	O15118-1.2	S847I	Neutral	0.438
NPC1	O15118-1.2	S847K	Neutral	0.341
NPC1	O15118-1.2	S847L	Neutral	0.447
NPC1	O15118-1.2	S847M	Neutral	0.391
NPC1	O15118-1.2	S847N	Neutral	0.24
NPC1	O15118-1.2	S847P	Neutral	0.383
NPC1	O15118-1.2	S847Q	Neutral	0.371
NPC1	O15118-1.2	S847R	Neutral	0.451
NPC1	O15118-1.2	S847T	Neutral	0.254
NPC1	O15118-1.2	S847V	Neutral	0.458
NPC1	O15118-1.2	S847W	Pathogenic	0.556
NPC1	O15118-1.2	S847Y	Pathogenic	0.534
NPC1	O15118-1.2	F848A	Neutral	0.339
NPC1	O15118-1.2	F848C	Neutral	0.364
NPC1	O15118-1.2	F848D	Neutral	0.313
NPC1	O15118-1.2	F848E	Neutral	0.299
NPC1	O15118-1.2	F848G	Neutral	0.433
NPC1	O15118-1.2	F848H	Neutral	0.195
NPC1	O15118-1.2	F848I	Neutral	0.215
NPC1	O15118-1.2	F848K	Neutral	0.245
NPC1	O15118-1.2	F848L	Neutral	0.211
NPC1	O15118-1.2	F848M	Neutral	0.186
NPC1	O15118-1.2	F848N	Neutral	0.319
NPC1	O15118-1.2	F848P	Pathogenic	0.525
NPC1	O15118-1.2	F848Q	Neutral	0.323
NPC1	O15118-1.2	F848R	Neutral	0.259
NPC1	O15118-1.2	F848S	Neutral	0.306
NPC1	O15118-1.2	F848T	Neutral	0.301
NPC1	O15118-1.2	F848V	Neutral	0.273
NPC1	O15118-1.2	F848W	Neutral	0.151
NPC1	O15118-1.2	F848Y	Neutral	0.06
NPC1	O15118-1.2	S849A	Pathogenic	0.507
NPC1	O15118-1.2	S849C	Pathogenic	0.65
NPC1	O15118-1.2	S849D	Pathogenic	0.588
NPC1	O15118-1.2	S849E	Pathogenic	0.625
NPC1	O15118-1.2	S849F	Pathogenic	0.737
NPC1	O15118-1.2	S849G	Pathogenic	0.653
NPC1	O15118-1.2	S849H	Pathogenic	0.749
NPC1	O15118-1.2	S849I	Pathogenic	0.723
NPC1	O15118-1.2	S849K	Pathogenic	0.634
NPC1	O15118-1.2	S849L	Pathogenic	0.73
NPC1	O15118-1.2	S849M	Pathogenic	0.682
NPC1	O15118-1.2	S849N	Pathogenic	0.514
NPC1	O15118-1.2	S849P	Pathogenic	0.675
NPC1	O15118-1.2	S849Q	Pathogenic	0.664
NPC1	O15118-1.2	S849R	Pathogenic	0.733
NPC1	O15118-1.2	S849T	Pathogenic	0.532
NPC1	O15118-1.2	S849V	Pathogenic	0.739
NPC1	O15118-1.2	S849W	Pathogenic	0.807
NPC1	O15118-1.2	S849Y	Pathogenic	0.793
NPC1	O15118-1.2	I850A	Neutral	0.255
NPC1	O15118-1.2	I850C	Neutral	0.276
NPC1	O15118-1.2	I850D	Neutral	0.309
NPC1	O15118-1.2	I850E	Neutral	0.295
NPC1	O15118-1.2	I850F	Neutral	0.223
NPC1	O15118-1.2	I850G	Pathogenic	0.524
NPC1	O15118-1.2	I850H	Neutral	0.339
NPC1	O15118-1.2	I850K	Neutral	0.267
NPC1	O15118-1.2	I850L	Neutral	0.108
NPC1	O15118-1.2	I850M	Neutral	0.132
NPC1	O15118-1.2	I850N	Neutral	0.314
NPC1	O15118-1.2	I850P	Neutral	0.424
NPC1	O15118-1.2	I850Q	Neutral	0.318
NPC1	O15118-1.2	I850R	Neutral	0.281
NPC1	O15118-1.2	I850S	Neutral	0.302
NPC1	O15118-1.2	I850T	Neutral	0.223
NPC1	O15118-1.2	I850V	Neutral	0.073
NPC1	O15118-1.2	I850W	Neutral	0.484
NPC1	O15118-1.2	I850Y	Neutral	0.25
NPC1	O15118-1.2	A851C	Neutral	0.496
NPC1	O15118-1.2	A851D	Pathogenic	0.657
NPC1	O15118-1.2	A851E	Pathogenic	0.603
NPC1	O15118-1.2	A851F	Pathogenic	0.686
NPC1	O15118-1.2	A851G	Pathogenic	0.526
NPC1	O15118-1.2	A851H	Pathogenic	0.753
NPC1	O15118-1.2	A851I	Pathogenic	0.581
NPC1	O15118-1.2	A851K	Pathogenic	0.613
NPC1	O15118-1.2	A851L	Pathogenic	0.589
NPC1	O15118-1.2	A851M	Pathogenic	0.626
NPC1	O15118-1.2	A851N	Pathogenic	0.676
NPC1	O15118-1.2	A851P	Pathogenic	0.618
NPC1	O15118-1.2	A851Q	Pathogenic	0.643
NPC1	O15118-1.2	A851R	Pathogenic	0.63
NPC1	O15118-1.2	A851S	Neutral	0.408
NPC1	O15118-1.2	A851T	Pathogenic	0.558
NPC1	O15118-1.2	A851V	Pathogenic	0.505
NPC1	O15118-1.2	A851W	Pathogenic	0.766
NPC1	O15118-1.2	A851Y	Pathogenic	0.749
NPC1	O15118-1.2	V852A	Neutral	0.264
NPC1	O15118-1.2	V852C	Neutral	0.37
NPC1	O15118-1.2	V852D	Neutral	0.408
NPC1	O15118-1.2	V852E	Neutral	0.316
NPC1	O15118-1.2	V852F	Neutral	0.36
NPC1	O15118-1.2	V852G	Pathogenic	0.536
NPC1	O15118-1.2	V852H	Neutral	0.481
NPC1	O15118-1.2	V852I	Neutral	0.101
NPC1	O15118-1.2	V852K	Neutral	0.324
NPC1	O15118-1.2	V852L	Neutral	0.2
NPC1	O15118-1.2	V852M	Neutral	0.226
NPC1	O15118-1.2	V852N	Neutral	0.415
NPC1	O15118-1.2	V852P	Neutral	0.436
NPC1	O15118-1.2	V852Q	Neutral	0.353
NPC1	O15118-1.2	V852R	Neutral	0.432
NPC1	O15118-1.2	V852S	Neutral	0.4
NPC1	O15118-1.2	V852T	Neutral	0.232
NPC1	O15118-1.2	V852W	Pathogenic	0.553
NPC1	O15118-1.2	V852Y	Neutral	0.393
NPC1	O15118-1.2	L853A	Neutral	0.107
NPC1	O15118-1.2	L853C	Neutral	0.118
NPC1	O15118-1.2	L853D	Neutral	0.187
NPC1	O15118-1.2	L853E	Neutral	0.128
NPC1	O15118-1.2	L853F	Neutral	0.087
NPC1	O15118-1.2	L853G	Neutral	0.278
NPC1	O15118-1.2	L853H	Neutral	0.152
NPC1	O15118-1.2	L853I	Neutral	0.039
NPC1	O15118-1.2	L853K	Neutral	0.08
NPC1	O15118-1.2	L853M	Neutral	0.035
NPC1	O15118-1.2	L853N	Neutral	0.138
NPC1	O15118-1.2	L853P	Neutral	0.205
NPC1	O15118-1.2	L853Q	Neutral	0.1
NPC1	O15118-1.2	L853R	Neutral	0.085
NPC1	O15118-1.2	L853S	Neutral	0.131
NPC1	O15118-1.2	L853T	Neutral	0.091
NPC1	O15118-1.2	L853V	Neutral	0.056
NPC1	O15118-1.2	L853W	Neutral	0.173
NPC1	O15118-1.2	L853Y	Neutral	0.104
NPC1	O15118-1.2	N854A	Neutral	0.495
NPC1	O15118-1.2	N854C	Pathogenic	0.506
NPC1	O15118-1.2	N854D	Neutral	0.254
NPC1	O15118-1.2	N854E	Neutral	0.354
NPC1	O15118-1.2	N854F	Neutral	0.483
NPC1	O15118-1.2	N854G	Neutral	0.36
NPC1	O15118-1.2	N854H	Neutral	0.238
NPC1	O15118-1.2	N854I	Neutral	0.465
NPC1	O15118-1.2	N854K	Neutral	0.364
NPC1	O15118-1.2	N854L	Neutral	0.474
NPC1	O15118-1.2	N854M	Neutral	0.417
NPC1	O15118-1.2	N854P	Neutral	0.426
NPC1	O15118-1.2	N854Q	Neutral	0.335
NPC1	O15118-1.2	N854R	Neutral	0.381
NPC1	O15118-1.2	N854S	Neutral	0.25
NPC1	O15118-1.2	N854T	Neutral	0.282
NPC1	O15118-1.2	N854V	Neutral	0.485
NPC1	O15118-1.2	N854W	Pathogenic	0.583
NPC1	O15118-1.2	N854Y	Neutral	0.465
NPC1	O15118-1.2	K855A	Pathogenic	0.57
NPC1	O15118-1.2	K855C	Pathogenic	0.671
NPC1	O15118-1.2	K855D	Pathogenic	0.621
NPC1	O15118-1.2	K855E	Neutral	0.394
NPC1	O15118-1.2	K855F	Pathogenic	0.537
NPC1	O15118-1.2	K855G	Pathogenic	0.708
NPC1	O15118-1.2	K855H	Pathogenic	0.508
NPC1	O15118-1.2	K855I	Pathogenic	0.553
NPC1	O15118-1.2	K855L	Neutral	0.465
NPC1	O15118-1.2	K855M	Neutral	0.409
NPC1	O15118-1.2	K855N	Pathogenic	0.506
NPC1	O15118-1.2	K855P	Pathogenic	0.502
NPC1	O15118-1.2	K855Q	Neutral	0.355
NPC1	O15118-1.2	K855R	Neutral	0.314
NPC1	O15118-1.2	K855S	Neutral	0.494
NPC1	O15118-1.2	K855T	Pathogenic	0.535
NPC1	O15118-1.2	K855V	Pathogenic	0.534
NPC1	O15118-1.2	K855W	Pathogenic	0.541
NPC1	O15118-1.2	K855Y	Pathogenic	0.519
NPC1	O15118-1.2	V856A	Pathogenic	0.691
NPC1	O15118-1.2	V856C	Pathogenic	0.786
NPC1	O15118-1.2	V856D	Pathogenic	0.812
NPC1	O15118-1.2	V856E	Pathogenic	0.742
NPC1	O15118-1.2	V856F	Pathogenic	0.778
NPC1	O15118-1.2	V856G	Pathogenic	0.878
NPC1	O15118-1.2	V856H	Pathogenic	0.852
NPC1	O15118-1.2	V856I	Neutral	0.411
NPC1	O15118-1.2	V856K	Pathogenic	0.75
NPC1	O15118-1.2	V856L	Pathogenic	0.61
NPC1	O15118-1.2	V856M	Pathogenic	0.646
NPC1	O15118-1.2	V856N	Pathogenic	0.815
NPC1	O15118-1.2	V856P	Pathogenic	0.829
NPC1	O15118-1.2	V856Q	Pathogenic	0.773
NPC1	O15118-1.2	V856R	Pathogenic	0.826
NPC1	O15118-1.2	V856S	Pathogenic	0.806
NPC1	O15118-1.2	V856T	Pathogenic	0.653
NPC1	O15118-1.2	V856W	Pathogenic	0.885
NPC1	O15118-1.2	V856Y	Pathogenic	0.802
NPC1	O15118-1.2	D857A	Pathogenic	0.567
NPC1	O15118-1.2	D857C	Pathogenic	0.579
NPC1	O15118-1.2	D857E	Neutral	0.27
NPC1	O15118-1.2	D857F	Pathogenic	0.571
NPC1	O15118-1.2	D857G	Pathogenic	0.526
NPC1	O15118-1.2	D857H	Neutral	0.491
NPC1	O15118-1.2	D857I	Pathogenic	0.553
NPC1	O15118-1.2	D857K	Pathogenic	0.572
NPC1	O15118-1.2	D857L	Pathogenic	0.654
NPC1	O15118-1.2	D857M	Pathogenic	0.6
NPC1	O15118-1.2	D857N	Neutral	0.332
NPC1	O15118-1.2	D857P	Neutral	0.404
NPC1	O15118-1.2	D857Q	Neutral	0.418
NPC1	O15118-1.2	D857R	Pathogenic	0.679
NPC1	O15118-1.2	D857S	Neutral	0.396
NPC1	O15118-1.2	D857T	Neutral	0.443
NPC1	O15118-1.2	D857V	Pathogenic	0.573
NPC1	O15118-1.2	D857W	Pathogenic	0.665
NPC1	O15118-1.2	D857Y	Pathogenic	0.645
NPC1	O15118-1.2	I858A	Pathogenic	0.851
NPC1	O15118-1.2	I858C	Pathogenic	0.865
NPC1	O15118-1.2	I858D	Pathogenic	0.882
NPC1	O15118-1.2	I858E	Pathogenic	0.875
NPC1	O15118-1.2	I858F	Pathogenic	0.828
NPC1	O15118-1.2	I858G	Pathogenic	0.949
NPC1	O15118-1.2	I858H	Pathogenic	0.896
NPC1	O15118-1.2	I858K	Pathogenic	0.859
NPC1	O15118-1.2	I858L	Pathogenic	0.669
NPC1	O15118-1.2	I858M	Pathogenic	0.718
NPC1	O15118-1.2	I858N	Pathogenic	0.885
NPC1	O15118-1.2	I858P	Pathogenic	0.925
NPC1	O15118-1.2	I858Q	Pathogenic	0.887
NPC1	O15118-1.2	I858R	Pathogenic	0.868
NPC1	O15118-1.2	I858S	Pathogenic	0.879
NPC1	O15118-1.2	I858T	Pathogenic	0.828
NPC1	O15118-1.2	I858V	Pathogenic	0.568
NPC1	O15118-1.2	I858W	Pathogenic	0.94
NPC1	O15118-1.2	I858Y	Pathogenic	0.848
NPC1	O15118-1.2	G859A	Pathogenic	0.937
NPC1	O15118-1.2	G859C	Pathogenic	0.977
NPC1	O15118-1.2	G859D	Pathogenic	0.956
NPC1	O15118-1.2	G859E	Pathogenic	0.974
NPC1	O15118-1.2	G859F	Pathogenic	0.978
NPC1	O15118-1.2	G859H	Pathogenic	0.979
NPC1	O15118-1.2	G859I	Pathogenic	0.984
NPC1	O15118-1.2	G859K	Pathogenic	0.975
NPC1	O15118-1.2	G859L	Pathogenic	0.984
NPC1	O15118-1.2	G859M	Pathogenic	0.98
NPC1	O15118-1.2	G859N	Pathogenic	0.941
NPC1	O15118-1.2	G859P	Pathogenic	0.97
NPC1	O15118-1.2	G859Q	Pathogenic	0.978
NPC1	O15118-1.2	G859R	Pathogenic	0.977
NPC1	O15118-1.2	G859S	Pathogenic	0.944
NPC1	O15118-1.2	G859T	Pathogenic	0.975
NPC1	O15118-1.2	G859V	Pathogenic	0.978
NPC1	O15118-1.2	G859W	Pathogenic	0.968
NPC1	O15118-1.2	G859Y	Pathogenic	0.983
NPC1	O15118-1.2	L860A	Pathogenic	0.941
NPC1	O15118-1.2	L860C	Pathogenic	0.947
NPC1	O15118-1.2	L860D	Pathogenic	0.968
NPC1	O15118-1.2	L860E	Pathogenic	0.951
NPC1	O15118-1.2	L860F	Pathogenic	0.927
NPC1	O15118-1.2	L860G	Pathogenic	0.981
NPC1	O15118-1.2	L860H	Pathogenic	0.96
NPC1	O15118-1.2	L860I	Pathogenic	0.845
NPC1	O15118-1.2	L860K	Pathogenic	0.92
NPC1	O15118-1.2	L860M	Pathogenic	0.828
NPC1	O15118-1.2	L860N	Pathogenic	0.955
NPC1	O15118-1.2	L860P	Pathogenic	0.972
NPC1	O15118-1.2	L860Q	Pathogenic	0.937
NPC1	O15118-1.2	L860R	Pathogenic	0.925
NPC1	O15118-1.2	L860S	Pathogenic	0.953
NPC1	O15118-1.2	L860T	Pathogenic	0.93
NPC1	O15118-1.2	L860V	Pathogenic	0.888
NPC1	O15118-1.2	L860W	Pathogenic	0.965
NPC1	O15118-1.2	L860Y	Pathogenic	0.94
NPC1	O15118-1.2	D861A	Pathogenic	0.949
NPC1	O15118-1.2	D861C	Pathogenic	0.951
NPC1	O15118-1.2	D861E	Pathogenic	0.84
NPC1	O15118-1.2	D861F	Pathogenic	0.95
NPC1	O15118-1.2	D861G	Pathogenic	0.94
NPC1	O15118-1.2	D861H	Pathogenic	0.932
NPC1	O15118-1.2	D861I	Pathogenic	0.946
NPC1	O15118-1.2	D861K	Pathogenic	0.95
NPC1	O15118-1.2	D861L	Pathogenic	0.964
NPC1	O15118-1.2	D861M	Pathogenic	0.955
NPC1	O15118-1.2	D861N	Pathogenic	0.876
NPC1	O15118-1.2	D861P	Pathogenic	0.906
NPC1	O15118-1.2	D861Q	Pathogenic	0.911
NPC1	O15118-1.2	D861R	Pathogenic	0.968
NPC1	O15118-1.2	D861S	Pathogenic	0.903
NPC1	O15118-1.2	D861T	Pathogenic	0.918
NPC1	O15118-1.2	D861V	Pathogenic	0.95
NPC1	O15118-1.2	D861W	Pathogenic	0.966
NPC1	O15118-1.2	D861Y	Pathogenic	0.963
NPC1	O15118-1.2	Q862A	Pathogenic	0.959
NPC1	O15118-1.2	Q862C	Pathogenic	0.973
NPC1	O15118-1.2	Q862D	Pathogenic	0.931
NPC1	O15118-1.2	Q862E	Pathogenic	0.854
NPC1	O15118-1.2	Q862F	Pathogenic	0.963
NPC1	O15118-1.2	Q862G	Pathogenic	0.977
NPC1	O15118-1.2	Q862H	Pathogenic	0.928
NPC1	O15118-1.2	Q862I	Pathogenic	0.961
NPC1	O15118-1.2	Q862K	Pathogenic	0.894
NPC1	O15118-1.2	Q862L	Pathogenic	0.945
NPC1	O15118-1.2	Q862M	Pathogenic	0.903
NPC1	O15118-1.2	Q862N	Pathogenic	0.933
NPC1	O15118-1.2	Q862P	Pathogenic	0.946
NPC1	O15118-1.2	Q862R	Pathogenic	0.901
NPC1	O15118-1.2	Q862S	Pathogenic	0.945
NPC1	O15118-1.2	Q862T	Pathogenic	0.953
NPC1	O15118-1.2	Q862V	Pathogenic	0.952
NPC1	O15118-1.2	Q862W	Pathogenic	0.948
NPC1	O15118-1.2	Q862Y	Pathogenic	0.943
NPC1	O15118-1.2	S863A	Neutral	0.287
NPC1	O15118-1.2	S863C	Neutral	0.421
NPC1	O15118-1.2	S863D	Neutral	0.359
NPC1	O15118-1.2	S863E	Neutral	0.395
NPC1	O15118-1.2	S863F	Pathogenic	0.524
NPC1	O15118-1.2	S863G	Neutral	0.424
NPC1	O15118-1.2	S863H	Pathogenic	0.539
NPC1	O15118-1.2	S863I	Pathogenic	0.506
NPC1	O15118-1.2	S863K	Neutral	0.405
NPC1	O15118-1.2	S863L	Pathogenic	0.514
NPC1	O15118-1.2	S863M	Neutral	0.457
NPC1	O15118-1.2	S863N	Neutral	0.293
NPC1	O15118-1.2	S863P	Neutral	0.448
NPC1	O15118-1.2	S863Q	Neutral	0.436
NPC1	O15118-1.2	S863R	Pathogenic	0.518
NPC1	O15118-1.2	S863T	Neutral	0.309
NPC1	O15118-1.2	S863V	Pathogenic	0.526
NPC1	O15118-1.2	S863W	Pathogenic	0.622
NPC1	O15118-1.2	S863Y	Pathogenic	0.6
NPC1	O15118-1.2	L864A	Pathogenic	0.91
NPC1	O15118-1.2	L864C	Pathogenic	0.919
NPC1	O15118-1.2	L864D	Pathogenic	0.951
NPC1	O15118-1.2	L864E	Pathogenic	0.925
NPC1	O15118-1.2	L864F	Pathogenic	0.889
NPC1	O15118-1.2	L864G	Pathogenic	0.97
NPC1	O15118-1.2	L864H	Pathogenic	0.938
NPC1	O15118-1.2	L864I	Pathogenic	0.776
NPC1	O15118-1.2	L864K	Pathogenic	0.88
NPC1	O15118-1.2	L864M	Pathogenic	0.754
NPC1	O15118-1.2	L864N	Pathogenic	0.931
NPC1	O15118-1.2	L864P	Pathogenic	0.956
NPC1	O15118-1.2	L864Q	Pathogenic	0.904
NPC1	O15118-1.2	L864R	Pathogenic	0.887
NPC1	O15118-1.2	L864S	Pathogenic	0.927
NPC1	O15118-1.2	L864T	Pathogenic	0.895
NPC1	O15118-1.2	L864V	Pathogenic	0.834
NPC1	O15118-1.2	L864W	Pathogenic	0.946
NPC1	O15118-1.2	L864Y	Pathogenic	0.908
NPC1	O15118-1.2	S865A	Pathogenic	0.782
NPC1	O15118-1.2	S865C	Pathogenic	0.866
NPC1	O15118-1.2	S865D	Pathogenic	0.833
NPC1	O15118-1.2	S865E	Pathogenic	0.853
NPC1	O15118-1.2	S865F	Pathogenic	0.907
NPC1	O15118-1.2	S865G	Pathogenic	0.868
NPC1	O15118-1.2	S865H	Pathogenic	0.912
NPC1	O15118-1.2	S865I	Pathogenic	0.901
NPC1	O15118-1.2	S865K	Pathogenic	0.858
NPC1	O15118-1.2	S865L	Pathogenic	0.904
NPC1	O15118-1.2	S865M	Pathogenic	0.882
NPC1	O15118-1.2	S865N	Pathogenic	0.787
NPC1	O15118-1.2	S865P	Pathogenic	0.879
NPC1	O15118-1.2	S865Q	Pathogenic	0.873
NPC1	O15118-1.2	S865R	Pathogenic	0.906
NPC1	O15118-1.2	S865T	Pathogenic	0.799
NPC1	O15118-1.2	S865V	Pathogenic	0.908
NPC1	O15118-1.2	S865W	Pathogenic	0.936
NPC1	O15118-1.2	S865Y	Pathogenic	0.93
NPC1	O15118-1.2	M866A	Pathogenic	0.947
NPC1	O15118-1.2	M866C	Pathogenic	0.953
NPC1	O15118-1.2	M866D	Pathogenic	0.959
NPC1	O15118-1.2	M866E	Pathogenic	0.938
NPC1	O15118-1.2	M866F	Pathogenic	0.913
NPC1	O15118-1.2	M866G	Pathogenic	0.975
NPC1	O15118-1.2	M866H	Pathogenic	0.948
NPC1	O15118-1.2	M866I	Pathogenic	0.869
NPC1	O15118-1.2	M866K	Pathogenic	0.899
NPC1	O15118-1.2	M866L	Pathogenic	0.824
NPC1	O15118-1.2	M866N	Pathogenic	0.943
NPC1	O15118-1.2	M866P	Pathogenic	0.964
NPC1	O15118-1.2	M866Q	Pathogenic	0.886
NPC1	O15118-1.2	M866R	Pathogenic	0.905
NPC1	O15118-1.2	M866S	Pathogenic	0.939
NPC1	O15118-1.2	M866T	Pathogenic	0.938
NPC1	O15118-1.2	M866V	Pathogenic	0.9
NPC1	O15118-1.2	M866W	Pathogenic	0.94
NPC1	O15118-1.2	M866Y	Pathogenic	0.946
NPC1	O15118-1.2	P867A	Pathogenic	0.953
NPC1	O15118-1.2	P867C	Pathogenic	0.976
NPC1	O15118-1.2	P867D	Pathogenic	0.925
NPC1	O15118-1.2	P867E	Pathogenic	0.935
NPC1	O15118-1.2	P867F	Pathogenic	0.983
NPC1	O15118-1.2	P867G	Pathogenic	0.968
NPC1	O15118-1.2	P867H	Pathogenic	0.967
NPC1	O15118-1.2	P867I	Pathogenic	0.974
NPC1	O15118-1.2	P867K	Pathogenic	0.938
NPC1	O15118-1.2	P867L	Pathogenic	0.975
NPC1	O15118-1.2	P867M	Pathogenic	0.969
NPC1	O15118-1.2	P867N	Pathogenic	0.952
NPC1	O15118-1.2	P867Q	Pathogenic	0.945
NPC1	O15118-1.2	P867R	Pathogenic	0.96
NPC1	O15118-1.2	P867S	Pathogenic	0.946
NPC1	O15118-1.2	P867T	Pathogenic	0.946
NPC1	O15118-1.2	P867V	Pathogenic	0.965
NPC1	O15118-1.2	P867W	Pathogenic	0.984
NPC1	O15118-1.2	P867Y	Pathogenic	0.982
NPC1	O15118-1.2	D868A	Pathogenic	0.588
NPC1	O15118-1.2	D868C	Pathogenic	0.6
NPC1	O15118-1.2	D868E	Neutral	0.287
NPC1	O15118-1.2	D868F	Pathogenic	0.592
NPC1	O15118-1.2	D868G	Pathogenic	0.547
NPC1	O15118-1.2	D868H	Pathogenic	0.512
NPC1	O15118-1.2	D868I	Pathogenic	0.575
NPC1	O15118-1.2	D868K	Pathogenic	0.593
NPC1	O15118-1.2	D868L	Pathogenic	0.673
NPC1	O15118-1.2	D868M	Pathogenic	0.62
NPC1	O15118-1.2	D868N	Neutral	0.351
NPC1	O15118-1.2	D868P	Neutral	0.425
NPC1	O15118-1.2	D868Q	Neutral	0.439
NPC1	O15118-1.2	D868R	Pathogenic	0.698
NPC1	O15118-1.2	D868S	Neutral	0.417
NPC1	O15118-1.2	D868T	Neutral	0.464
NPC1	O15118-1.2	D868V	Pathogenic	0.594
NPC1	O15118-1.2	D868W	Pathogenic	0.684
NPC1	O15118-1.2	D868Y	Pathogenic	0.665
NPC1	O15118-1.2	D869A	Pathogenic	0.958
NPC1	O15118-1.2	D869C	Pathogenic	0.96
NPC1	O15118-1.2	D869E	Pathogenic	0.865
NPC1	O15118-1.2	D869F	Pathogenic	0.959
NPC1	O15118-1.2	D869G	Pathogenic	0.951
NPC1	O15118-1.2	D869H	Pathogenic	0.944
NPC1	O15118-1.2	D869I	Pathogenic	0.956
NPC1	O15118-1.2	D869K	Pathogenic	0.959
NPC1	O15118-1.2	D869L	Pathogenic	0.97
NPC1	O15118-1.2	D869M	Pathogenic	0.963
NPC1	O15118-1.2	D869N	Pathogenic	0.896
NPC1	O15118-1.2	D869P	Pathogenic	0.922
NPC1	O15118-1.2	D869Q	Pathogenic	0.926
NPC1	O15118-1.2	D869R	Pathogenic	0.974
NPC1	O15118-1.2	D869S	Pathogenic	0.919
NPC1	O15118-1.2	D869T	Pathogenic	0.932
NPC1	O15118-1.2	D869V	Pathogenic	0.959
NPC1	O15118-1.2	D869W	Pathogenic	0.972
NPC1	O15118-1.2	D869Y	Pathogenic	0.969
NPC1	O15118-1.2	S870A	Pathogenic	0.904
NPC1	O15118-1.2	S870C	Pathogenic	0.944
NPC1	O15118-1.2	S870D	Pathogenic	0.929
NPC1	O15118-1.2	S870E	Pathogenic	0.939
NPC1	O15118-1.2	S870F	Pathogenic	0.963
NPC1	O15118-1.2	S870G	Pathogenic	0.945
NPC1	O15118-1.2	S870H	Pathogenic	0.965
NPC1	O15118-1.2	S870I	Pathogenic	0.96
NPC1	O15118-1.2	S870K	Pathogenic	0.941
NPC1	O15118-1.2	S870L	Pathogenic	0.961
NPC1	O15118-1.2	S870M	Pathogenic	0.952
NPC1	O15118-1.2	S870N	Pathogenic	0.907
NPC1	O15118-1.2	S870P	Pathogenic	0.95
NPC1	O15118-1.2	S870Q	Pathogenic	0.948
NPC1	O15118-1.2	S870R	Pathogenic	0.962
NPC1	O15118-1.2	S870T	Pathogenic	0.913
NPC1	O15118-1.2	S870V	Pathogenic	0.963
NPC1	O15118-1.2	S870W	Pathogenic	0.975
NPC1	O15118-1.2	S870Y	Pathogenic	0.972
NPC1	O15118-1.2	Y871A	Pathogenic	0.945
NPC1	O15118-1.2	Y871C	Pathogenic	0.949
NPC1	O15118-1.2	Y871D	Pathogenic	0.938
NPC1	O15118-1.2	Y871E	Pathogenic	0.906
NPC1	O15118-1.2	Y871F	Pathogenic	0.608
NPC1	O15118-1.2	Y871G	Pathogenic	0.962
NPC1	O15118-1.2	Y871H	Pathogenic	0.717
NPC1	O15118-1.2	Y871I	Pathogenic	0.885
NPC1	O15118-1.2	Y871K	Pathogenic	0.88
NPC1	O15118-1.2	Y871L	Pathogenic	0.889
NPC1	O15118-1.2	Y871M	Pathogenic	0.903
NPC1	O15118-1.2	Y871N	Pathogenic	0.914
NPC1	O15118-1.2	Y871P	Pathogenic	0.962
NPC1	O15118-1.2	Y871Q	Pathogenic	0.88
NPC1	O15118-1.2	Y871R	Pathogenic	0.881
NPC1	O15118-1.2	Y871S	Pathogenic	0.936
NPC1	O15118-1.2	Y871T	Pathogenic	0.935
NPC1	O15118-1.2	Y871V	Pathogenic	0.913
NPC1	O15118-1.2	Y871W	Pathogenic	0.683
NPC1	O15118-1.2	M872A	Pathogenic	0.799
NPC1	O15118-1.2	M872C	Pathogenic	0.816
NPC1	O15118-1.2	M872D	Pathogenic	0.839
NPC1	O15118-1.2	M872E	Pathogenic	0.768
NPC1	O15118-1.2	M872F	Pathogenic	0.698
NPC1	O15118-1.2	M872G	Pathogenic	0.897
NPC1	O15118-1.2	M872H	Pathogenic	0.802
NPC1	O15118-1.2	M872I	Pathogenic	0.594
NPC1	O15118-1.2	M872K	Pathogenic	0.662
NPC1	O15118-1.2	M872L	Pathogenic	0.507
NPC1	O15118-1.2	M872N	Pathogenic	0.784
NPC1	O15118-1.2	M872P	Pathogenic	0.854
NPC1	O15118-1.2	M872Q	Pathogenic	0.631
NPC1	O15118-1.2	M872R	Pathogenic	0.678
NPC1	O15118-1.2	M872S	Pathogenic	0.774
NPC1	O15118-1.2	M872T	Pathogenic	0.77
NPC1	O15118-1.2	M872V	Pathogenic	0.664
NPC1	O15118-1.2	M872W	Pathogenic	0.776
NPC1	O15118-1.2	M872Y	Pathogenic	0.795
NPC1	O15118-1.2	V873A	Neutral	0.348
NPC1	O15118-1.2	V873C	Neutral	0.467
NPC1	O15118-1.2	V873D	Pathogenic	0.506
NPC1	O15118-1.2	V873E	Neutral	0.407
NPC1	O15118-1.2	V873F	Neutral	0.455
NPC1	O15118-1.2	V873G	Pathogenic	0.632
NPC1	O15118-1.2	V873H	Pathogenic	0.579
NPC1	O15118-1.2	V873I	Neutral	0.143
NPC1	O15118-1.2	V873K	Neutral	0.417
NPC1	O15118-1.2	V873L	Neutral	0.271
NPC1	O15118-1.2	V873M	Neutral	0.303
NPC1	O15118-1.2	V873N	Pathogenic	0.513
NPC1	O15118-1.2	V873P	Pathogenic	0.535
NPC1	O15118-1.2	V873Q	Neutral	0.448
NPC1	O15118-1.2	V873R	Pathogenic	0.531
NPC1	O15118-1.2	V873S	Neutral	0.498
NPC1	O15118-1.2	V873T	Neutral	0.309
NPC1	O15118-1.2	V873W	Pathogenic	0.648
NPC1	O15118-1.2	V873Y	Neutral	0.491
NPC1	O15118-1.2	D874A	Pathogenic	0.613
NPC1	O15118-1.2	D874C	Pathogenic	0.624
NPC1	O15118-1.2	D874E	Neutral	0.309
NPC1	O15118-1.2	D874F	Pathogenic	0.617
NPC1	O15118-1.2	D874G	Pathogenic	0.573
NPC1	O15118-1.2	D874H	Pathogenic	0.538
NPC1	O15118-1.2	D874I	Pathogenic	0.6
NPC1	O15118-1.2	D874K	Pathogenic	0.618
NPC1	O15118-1.2	D874L	Pathogenic	0.695
NPC1	O15118-1.2	D874M	Pathogenic	0.644
NPC1	O15118-1.2	D874N	Neutral	0.376
NPC1	O15118-1.2	D874P	Neutral	0.45
NPC1	O15118-1.2	D874Q	Neutral	0.465
NPC1	O15118-1.2	D874R	Pathogenic	0.719
NPC1	O15118-1.2	D874S	Neutral	0.442
NPC1	O15118-1.2	D874T	Neutral	0.49
NPC1	O15118-1.2	D874V	Pathogenic	0.619
NPC1	O15118-1.2	D874W	Pathogenic	0.706
NPC1	O15118-1.2	D874Y	Pathogenic	0.687
NPC1	O15118-1.2	Y875A	Pathogenic	0.97
NPC1	O15118-1.2	Y875C	Pathogenic	0.973
NPC1	O15118-1.2	Y875D	Pathogenic	0.966
NPC1	O15118-1.2	Y875E	Pathogenic	0.948
NPC1	O15118-1.2	Y875F	Pathogenic	0.745
NPC1	O15118-1.2	Y875G	Pathogenic	0.98
NPC1	O15118-1.2	Y875H	Pathogenic	0.827
NPC1	O15118-1.2	Y875I	Pathogenic	0.936
NPC1	O15118-1.2	Y875K	Pathogenic	0.933
NPC1	O15118-1.2	Y875L	Pathogenic	0.938
NPC1	O15118-1.2	Y875M	Pathogenic	0.946
NPC1	O15118-1.2	Y875N	Pathogenic	0.952
NPC1	O15118-1.2	Y875P	Pathogenic	0.979
NPC1	O15118-1.2	Y875Q	Pathogenic	0.933
NPC1	O15118-1.2	Y875R	Pathogenic	0.933
NPC1	O15118-1.2	Y875S	Pathogenic	0.965
NPC1	O15118-1.2	Y875T	Pathogenic	0.964
NPC1	O15118-1.2	Y875V	Pathogenic	0.952
NPC1	O15118-1.2	Y875W	Pathogenic	0.803
NPC1	O15118-1.2	F876A	Pathogenic	0.965
NPC1	O15118-1.2	F876C	Pathogenic	0.968
NPC1	O15118-1.2	F876D	Pathogenic	0.96
NPC1	O15118-1.2	F876E	Pathogenic	0.958
NPC1	O15118-1.2	F876G	Pathogenic	0.976
NPC1	O15118-1.2	F876H	Pathogenic	0.928
NPC1	O15118-1.2	F876I	Pathogenic	0.935
NPC1	O15118-1.2	F876K	Pathogenic	0.945
NPC1	O15118-1.2	F876L	Pathogenic	0.934
NPC1	O15118-1.2	F876M	Pathogenic	0.924
NPC1	O15118-1.2	F876N	Pathogenic	0.961
NPC1	O15118-1.2	F876P	Pathogenic	0.983
NPC1	O15118-1.2	F876Q	Pathogenic	0.962
NPC1	O15118-1.2	F876R	Pathogenic	0.949
NPC1	O15118-1.2	F876S	Pathogenic	0.959
NPC1	O15118-1.2	F876T	Pathogenic	0.958
NPC1	O15118-1.2	F876V	Pathogenic	0.952
NPC1	O15118-1.2	F876W	Pathogenic	0.904
NPC1	O15118-1.2	F876Y	Pathogenic	0.771
NPC1	O15118-1.2	K877A	Neutral	0.422
NPC1	O15118-1.2	K877C	Pathogenic	0.529
NPC1	O15118-1.2	K877D	Neutral	0.474
NPC1	O15118-1.2	K877E	Neutral	0.264
NPC1	O15118-1.2	K877F	Neutral	0.39
NPC1	O15118-1.2	K877G	Pathogenic	0.571
NPC1	O15118-1.2	K877H	Neutral	0.362
NPC1	O15118-1.2	K877I	Neutral	0.405
NPC1	O15118-1.2	K877L	Neutral	0.323
NPC1	O15118-1.2	K877M	Neutral	0.275
NPC1	O15118-1.2	K877N	Neutral	0.36
NPC1	O15118-1.2	K877P	Neutral	0.356
NPC1	O15118-1.2	K877Q	Neutral	0.232
NPC1	O15118-1.2	K877R	Neutral	0.201
NPC1	O15118-1.2	K877S	Neutral	0.349
NPC1	O15118-1.2	K877T	Neutral	0.388
NPC1	O15118-1.2	K877V	Neutral	0.386
NPC1	O15118-1.2	K877W	Neutral	0.394
NPC1	O15118-1.2	K877Y	Neutral	0.372
NPC1	O15118-1.2	S878A	Neutral	0.158
NPC1	O15118-1.2	S878C	Neutral	0.253
NPC1	O15118-1.2	S878D	Neutral	0.207
NPC1	O15118-1.2	S878E	Neutral	0.233
NPC1	O15118-1.2	S878F	Neutral	0.339
NPC1	O15118-1.2	S878G	Neutral	0.256
NPC1	O15118-1.2	S878H	Neutral	0.353
NPC1	O15118-1.2	S878I	Neutral	0.323
NPC1	O15118-1.2	S878K	Neutral	0.241
NPC1	O15118-1.2	S878L	Neutral	0.331
NPC1	O15118-1.2	S878M	Neutral	0.282
NPC1	O15118-1.2	S878N	Neutral	0.162
NPC1	O15118-1.2	S878P	Neutral	0.275
NPC1	O15118-1.2	S878Q	Neutral	0.265
NPC1	O15118-1.2	S878R	Neutral	0.334
NPC1	O15118-1.2	S878T	Neutral	0.172
NPC1	O15118-1.2	S878V	Neutral	0.341
NPC1	O15118-1.2	S878W	Neutral	0.434
NPC1	O15118-1.2	S878Y	Neutral	0.412
NPC1	O15118-1.2	I879A	Pathogenic	0.645
NPC1	O15118-1.2	I879C	Pathogenic	0.67
NPC1	O15118-1.2	I879D	Pathogenic	0.704
NPC1	O15118-1.2	I879E	Pathogenic	0.69
NPC1	O15118-1.2	I879F	Pathogenic	0.605
NPC1	O15118-1.2	I879G	Pathogenic	0.854
NPC1	O15118-1.2	I879H	Pathogenic	0.732
NPC1	O15118-1.2	I879K	Pathogenic	0.659
NPC1	O15118-1.2	I879L	Neutral	0.391
NPC1	O15118-1.2	I879M	Neutral	0.447
NPC1	O15118-1.2	I879N	Pathogenic	0.709
NPC1	O15118-1.2	I879P	Pathogenic	0.797
NPC1	O15118-1.2	I879Q	Pathogenic	0.713
NPC1	O15118-1.2	I879R	Pathogenic	0.676
NPC1	O15118-1.2	I879S	Pathogenic	0.697
NPC1	O15118-1.2	I879T	Pathogenic	0.604
NPC1	O15118-1.2	I879V	Neutral	0.295
NPC1	O15118-1.2	I879W	Pathogenic	0.833
NPC1	O15118-1.2	I879Y	Pathogenic	0.639
NPC1	O15118-1.2	S880A	Neutral	0.211
NPC1	O15118-1.2	S880C	Neutral	0.326
NPC1	O15118-1.2	S880D	Neutral	0.271
NPC1	O15118-1.2	S880E	Neutral	0.303
NPC1	O15118-1.2	S880F	Neutral	0.422
NPC1	O15118-1.2	S880G	Neutral	0.329
NPC1	O15118-1.2	S880H	Neutral	0.438
NPC1	O15118-1.2	S880I	Neutral	0.405
NPC1	O15118-1.2	S880K	Neutral	0.311
NPC1	O15118-1.2	S880L	Neutral	0.413
NPC1	O15118-1.2	S880M	Neutral	0.359
NPC1	O15118-1.2	S880N	Neutral	0.216
NPC1	O15118-1.2	S880P	Neutral	0.351
NPC1	O15118-1.2	S880Q	Neutral	0.339
NPC1	O15118-1.2	S880R	Neutral	0.417
NPC1	O15118-1.2	S880T	Neutral	0.229
NPC1	O15118-1.2	S880V	Neutral	0.425
NPC1	O15118-1.2	S880W	Pathogenic	0.522
NPC1	O15118-1.2	S880Y	Neutral	0.5
NPC1	O15118-1.2	Q881A	Neutral	0.377
NPC1	O15118-1.2	Q881C	Neutral	0.482
NPC1	O15118-1.2	Q881D	Neutral	0.261
NPC1	O15118-1.2	Q881E	Neutral	0.133
NPC1	O15118-1.2	Q881F	Neutral	0.406
NPC1	O15118-1.2	Q881G	Pathogenic	0.525
NPC1	O15118-1.2	Q881H	Neutral	0.252
NPC1	O15118-1.2	Q881I	Neutral	0.389
NPC1	O15118-1.2	Q881K	Neutral	0.181
NPC1	O15118-1.2	Q881L	Neutral	0.309
NPC1	O15118-1.2	Q881M	Neutral	0.195
NPC1	O15118-1.2	Q881N	Neutral	0.266
NPC1	O15118-1.2	Q881P	Neutral	0.315
NPC1	O15118-1.2	Q881R	Neutral	0.192
NPC1	O15118-1.2	Q881S	Neutral	0.308
NPC1	O15118-1.2	Q881T	Neutral	0.344
NPC1	O15118-1.2	Q881V	Neutral	0.343
NPC1	O15118-1.2	Q881W	Neutral	0.321
NPC1	O15118-1.2	Q881Y	Neutral	0.301
NPC1	O15118-1.2	Y882A	Pathogenic	0.953
NPC1	O15118-1.2	Y882C	Pathogenic	0.957
NPC1	O15118-1.2	Y882D	Pathogenic	0.947
NPC1	O15118-1.2	Y882E	Pathogenic	0.92
NPC1	O15118-1.2	Y882F	Pathogenic	0.647
NPC1	O15118-1.2	Y882G	Pathogenic	0.968
NPC1	O15118-1.2	Y882H	Pathogenic	0.749
NPC1	O15118-1.2	Y882I	Pathogenic	0.901
NPC1	O15118-1.2	Y882K	Pathogenic	0.897
NPC1	O15118-1.2	Y882L	Pathogenic	0.904
NPC1	O15118-1.2	Y882M	Pathogenic	0.917
NPC1	O15118-1.2	Y882N	Pathogenic	0.926
NPC1	O15118-1.2	Y882P	Pathogenic	0.967
NPC1	O15118-1.2	Y882Q	Pathogenic	0.897
NPC1	O15118-1.2	Y882R	Pathogenic	0.897
NPC1	O15118-1.2	Y882S	Pathogenic	0.946
NPC1	O15118-1.2	Y882T	Pathogenic	0.944
NPC1	O15118-1.2	Y882V	Pathogenic	0.926
NPC1	O15118-1.2	Y882W	Pathogenic	0.718
NPC1	O15118-1.2	L883A	Pathogenic	0.901
NPC1	O15118-1.2	L883C	Pathogenic	0.91
NPC1	O15118-1.2	L883D	Pathogenic	0.946
NPC1	O15118-1.2	L883E	Pathogenic	0.918
NPC1	O15118-1.2	L883F	Pathogenic	0.878
NPC1	O15118-1.2	L883G	Pathogenic	0.967
NPC1	O15118-1.2	L883H	Pathogenic	0.932
NPC1	O15118-1.2	L883I	Pathogenic	0.756
NPC1	O15118-1.2	L883K	Pathogenic	0.868
NPC1	O15118-1.2	L883M	Pathogenic	0.733
NPC1	O15118-1.2	L883N	Pathogenic	0.924
NPC1	O15118-1.2	L883P	Pathogenic	0.951
NPC1	O15118-1.2	L883Q	Pathogenic	0.894
NPC1	O15118-1.2	L883R	Pathogenic	0.876
NPC1	O15118-1.2	L883S	Pathogenic	0.92
NPC1	O15118-1.2	L883T	Pathogenic	0.884
NPC1	O15118-1.2	L883V	Pathogenic	0.819
NPC1	O15118-1.2	L883W	Pathogenic	0.941
NPC1	O15118-1.2	L883Y	Pathogenic	0.898
NPC1	O15118-1.2	H884A	Pathogenic	0.849
NPC1	O15118-1.2	H884C	Pathogenic	0.855
NPC1	O15118-1.2	H884D	Pathogenic	0.722
NPC1	O15118-1.2	H884E	Pathogenic	0.624
NPC1	O15118-1.2	H884F	Pathogenic	0.656
NPC1	O15118-1.2	H884G	Pathogenic	0.865
NPC1	O15118-1.2	H884I	Pathogenic	0.793
NPC1	O15118-1.2	H884K	Pathogenic	0.695
NPC1	O15118-1.2	H884L	Pathogenic	0.799
NPC1	O15118-1.2	H884M	Pathogenic	0.759
NPC1	O15118-1.2	H884N	Pathogenic	0.552
NPC1	O15118-1.2	H884P	Pathogenic	0.81
NPC1	O15118-1.2	H884Q	Pathogenic	0.649
NPC1	O15118-1.2	H884R	Pathogenic	0.625
NPC1	O15118-1.2	H884S	Pathogenic	0.787
NPC1	O15118-1.2	H884T	Pathogenic	0.83
NPC1	O15118-1.2	H884V	Pathogenic	0.83
NPC1	O15118-1.2	H884W	Pathogenic	0.74
NPC1	O15118-1.2	H884Y	Neutral	0.45
NPC1	O15118-1.2	A885C	Neutral	0.448
NPC1	O15118-1.2	A885D	Pathogenic	0.613
NPC1	O15118-1.2	A885E	Pathogenic	0.557
NPC1	O15118-1.2	A885F	Pathogenic	0.644
NPC1	O15118-1.2	A885G	Neutral	0.479
NPC1	O15118-1.2	A885H	Pathogenic	0.716
NPC1	O15118-1.2	A885I	Pathogenic	0.534
NPC1	O15118-1.2	A885K	Pathogenic	0.567
NPC1	O15118-1.2	A885L	Pathogenic	0.542
NPC1	O15118-1.2	A885M	Pathogenic	0.581
NPC1	O15118-1.2	A885N	Pathogenic	0.633
NPC1	O15118-1.2	A885P	Pathogenic	0.572
NPC1	O15118-1.2	A885Q	Pathogenic	0.598
NPC1	O15118-1.2	A885R	Pathogenic	0.585
NPC1	O15118-1.2	A885S	Neutral	0.363
NPC1	O15118-1.2	A885T	Pathogenic	0.511
NPC1	O15118-1.2	A885V	Neutral	0.458
NPC1	O15118-1.2	A885W	Pathogenic	0.73
NPC1	O15118-1.2	A885Y	Pathogenic	0.712
NPC1	O15118-1.2	G886A	Pathogenic	0.944
NPC1	O15118-1.2	G886C	Pathogenic	0.98
NPC1	O15118-1.2	G886D	Pathogenic	0.961
NPC1	O15118-1.2	G886E	Pathogenic	0.977
NPC1	O15118-1.2	G886F	Pathogenic	0.98
NPC1	O15118-1.2	G886H	Pathogenic	0.981
NPC1	O15118-1.2	G886I	Pathogenic	0.985
NPC1	O15118-1.2	G886K	Pathogenic	0.978
NPC1	O15118-1.2	G886L	Pathogenic	0.986
NPC1	O15118-1.2	G886M	Pathogenic	0.982
NPC1	O15118-1.2	G886N	Pathogenic	0.948
NPC1	O15118-1.2	G886P	Pathogenic	0.973
NPC1	O15118-1.2	G886Q	Pathogenic	0.98
NPC1	O15118-1.2	G886R	Pathogenic	0.979
NPC1	O15118-1.2	G886S	Pathogenic	0.95
NPC1	O15118-1.2	G886T	Pathogenic	0.977
NPC1	O15118-1.2	G886V	Pathogenic	0.98
NPC1	O15118-1.2	G886W	Pathogenic	0.972
NPC1	O15118-1.2	G886Y	Pathogenic	0.985
NPC1	O15118-1.2	P887A	Pathogenic	0.847
NPC1	O15118-1.2	P887C	Pathogenic	0.918
NPC1	O15118-1.2	P887D	Pathogenic	0.773
NPC1	O15118-1.2	P887E	Pathogenic	0.798
NPC1	O15118-1.2	P887F	Pathogenic	0.942
NPC1	O15118-1.2	P887G	Pathogenic	0.892
NPC1	O15118-1.2	P887H	Pathogenic	0.888
NPC1	O15118-1.2	P887I	Pathogenic	0.911
NPC1	O15118-1.2	P887K	Pathogenic	0.805
NPC1	O15118-1.2	P887L	Pathogenic	0.914
NPC1	O15118-1.2	P887M	Pathogenic	0.894
NPC1	O15118-1.2	P887N	Pathogenic	0.845
NPC1	O15118-1.2	P887Q	Pathogenic	0.824
NPC1	O15118-1.2	P887R	Pathogenic	0.867
NPC1	O15118-1.2	P887S	Pathogenic	0.827
NPC1	O15118-1.2	P887T	Pathogenic	0.829
NPC1	O15118-1.2	P887V	Pathogenic	0.883
NPC1	O15118-1.2	P887W	Pathogenic	0.943
NPC1	O15118-1.2	P887Y	Pathogenic	0.938
NPC1	O15118-1.2	P888A	Pathogenic	0.964
NPC1	O15118-1.2	P888C	Pathogenic	0.982
NPC1	O15118-1.2	P888D	Pathogenic	0.943
NPC1	O15118-1.2	P888E	Pathogenic	0.951
NPC1	O15118-1.2	P888F	Pathogenic	0.988
NPC1	O15118-1.2	P888G	Pathogenic	0.976
NPC1	O15118-1.2	P888H	Pathogenic	0.975
NPC1	O15118-1.2	P888I	Pathogenic	0.98
NPC1	O15118-1.2	P888K	Pathogenic	0.953
NPC1	O15118-1.2	P888L	Pathogenic	0.981
NPC1	O15118-1.2	P888M	Pathogenic	0.976
NPC1	O15118-1.2	P888N	Pathogenic	0.964
NPC1	O15118-1.2	P888Q	Pathogenic	0.958
NPC1	O15118-1.2	P888R	Pathogenic	0.97
NPC1	O15118-1.2	P888S	Pathogenic	0.959
NPC1	O15118-1.2	P888T	Pathogenic	0.959
NPC1	O15118-1.2	P888V	Pathogenic	0.974
NPC1	O15118-1.2	P888W	Pathogenic	0.988
NPC1	O15118-1.2	P888Y	Pathogenic	0.987
NPC1	O15118-1.2	V889A	Pathogenic	0.804
NPC1	O15118-1.2	V889C	Pathogenic	0.871
NPC1	O15118-1.2	V889D	Pathogenic	0.887
NPC1	O15118-1.2	V889E	Pathogenic	0.841
NPC1	O15118-1.2	V889F	Pathogenic	0.865
NPC1	O15118-1.2	V889G	Pathogenic	0.93
NPC1	O15118-1.2	V889H	Pathogenic	0.914
NPC1	O15118-1.2	V889I	Pathogenic	0.561
NPC1	O15118-1.2	V889K	Pathogenic	0.846
NPC1	O15118-1.2	V889L	Pathogenic	0.741
NPC1	O15118-1.2	V889M	Pathogenic	0.77
NPC1	O15118-1.2	V889N	Pathogenic	0.89
NPC1	O15118-1.2	V889P	Pathogenic	0.898
NPC1	O15118-1.2	V889Q	Pathogenic	0.862
NPC1	O15118-1.2	V889R	Pathogenic	0.897
NPC1	O15118-1.2	V889S	Pathogenic	0.884
NPC1	O15118-1.2	V889T	Pathogenic	0.775
NPC1	O15118-1.2	V889W	Pathogenic	0.934
NPC1	O15118-1.2	V889Y	Pathogenic	0.881
NPC1	O15118-1.2	Y890A	Pathogenic	0.982
NPC1	O15118-1.2	Y890C	Pathogenic	0.983
NPC1	O15118-1.2	Y890D	Pathogenic	0.979
NPC1	O15118-1.2	Y890E	Pathogenic	0.968
NPC1	O15118-1.2	Y890F	Pathogenic	0.83
NPC1	O15118-1.2	Y890G	Pathogenic	0.988
NPC1	O15118-1.2	Y890H	Pathogenic	0.888
NPC1	O15118-1.2	Y890I	Pathogenic	0.96
NPC1	O15118-1.2	Y890K	Pathogenic	0.959
NPC1	O15118-1.2	Y890L	Pathogenic	0.962
NPC1	O15118-1.2	Y890M	Pathogenic	0.967
NPC1	O15118-1.2	Y890N	Pathogenic	0.971
NPC1	O15118-1.2	Y890P	Pathogenic	0.987
NPC1	O15118-1.2	Y890Q	Pathogenic	0.958
NPC1	O15118-1.2	Y890R	Pathogenic	0.959
NPC1	O15118-1.2	Y890S	Pathogenic	0.979
NPC1	O15118-1.2	Y890T	Pathogenic	0.978
NPC1	O15118-1.2	Y890V	Pathogenic	0.971
NPC1	O15118-1.2	Y890W	Pathogenic	0.871
NPC1	O15118-1.2	F891A	Pathogenic	0.97
NPC1	O15118-1.2	F891C	Pathogenic	0.973
NPC1	O15118-1.2	F891D	Pathogenic	0.967
NPC1	O15118-1.2	F891E	Pathogenic	0.965
NPC1	O15118-1.2	F891G	Pathogenic	0.98
NPC1	O15118-1.2	F891H	Pathogenic	0.939
NPC1	O15118-1.2	F891I	Pathogenic	0.946
NPC1	O15118-1.2	F891K	Pathogenic	0.954
NPC1	O15118-1.2	F891L	Pathogenic	0.945
NPC1	O15118-1.2	F891M	Pathogenic	0.936
NPC1	O15118-1.2	F891N	Pathogenic	0.968
NPC1	O15118-1.2	F891P	Pathogenic	0.986
NPC1	O15118-1.2	F891Q	Pathogenic	0.968
NPC1	O15118-1.2	F891R	Pathogenic	0.957
NPC1	O15118-1.2	F891S	Pathogenic	0.966
NPC1	O15118-1.2	F891T	Pathogenic	0.965
NPC1	O15118-1.2	F891V	Pathogenic	0.96
NPC1	O15118-1.2	F891W	Pathogenic	0.919
NPC1	O15118-1.2	F891Y	Pathogenic	0.802
NPC1	O15118-1.2	V892A	Pathogenic	0.934
NPC1	O15118-1.2	V892C	Pathogenic	0.959
NPC1	O15118-1.2	V892D	Pathogenic	0.965
NPC1	O15118-1.2	V892E	Pathogenic	0.948
NPC1	O15118-1.2	V892F	Pathogenic	0.957
NPC1	O15118-1.2	V892G	Pathogenic	0.979
NPC1	O15118-1.2	V892H	Pathogenic	0.973
NPC1	O15118-1.2	V892I	Pathogenic	0.816
NPC1	O15118-1.2	V892K	Pathogenic	0.95
NPC1	O15118-1.2	V892L	Pathogenic	0.908
NPC1	O15118-1.2	V892M	Pathogenic	0.921
NPC1	O15118-1.2	V892N	Pathogenic	0.966
NPC1	O15118-1.2	V892P	Pathogenic	0.968
NPC1	O15118-1.2	V892Q	Pathogenic	0.956
NPC1	O15118-1.2	V892R	Pathogenic	0.968
NPC1	O15118-1.2	V892S	Pathogenic	0.964
NPC1	O15118-1.2	V892T	Pathogenic	0.923
NPC1	O15118-1.2	V892W	Pathogenic	0.98
NPC1	O15118-1.2	V892Y	Pathogenic	0.962
NPC1	O15118-1.2	L893A	Pathogenic	0.691
NPC1	O15118-1.2	L893C	Pathogenic	0.714
NPC1	O15118-1.2	L893D	Pathogenic	0.811
NPC1	O15118-1.2	L893E	Pathogenic	0.733
NPC1	O15118-1.2	L893F	Pathogenic	0.64
NPC1	O15118-1.2	L893G	Pathogenic	0.878
NPC1	O15118-1.2	L893H	Pathogenic	0.77
NPC1	O15118-1.2	L893I	Neutral	0.433
NPC1	O15118-1.2	L893K	Pathogenic	0.618
NPC1	O15118-1.2	L893M	Neutral	0.404
NPC1	O15118-1.2	L893N	Pathogenic	0.75
NPC1	O15118-1.2	L893P	Pathogenic	0.828
NPC1	O15118-1.2	L893Q	Pathogenic	0.675
NPC1	O15118-1.2	L893R	Pathogenic	0.635
NPC1	O15118-1.2	L893S	Pathogenic	0.739
NPC1	O15118-1.2	L893T	Pathogenic	0.653
NPC1	O15118-1.2	L893V	Pathogenic	0.526
NPC1	O15118-1.2	L893W	Pathogenic	0.796
NPC1	O15118-1.2	L893Y	Pathogenic	0.686
NPC1	O15118-1.2	E894A	Pathogenic	0.685
NPC1	O15118-1.2	E894C	Pathogenic	0.831
NPC1	O15118-1.2	E894D	Neutral	0.437
NPC1	O15118-1.2	E894F	Pathogenic	0.723
NPC1	O15118-1.2	E894G	Pathogenic	0.799
NPC1	O15118-1.2	E894H	Pathogenic	0.562
NPC1	O15118-1.2	E894I	Pathogenic	0.709
NPC1	O15118-1.2	E894K	Pathogenic	0.526
NPC1	O15118-1.2	E894L	Pathogenic	0.716
NPC1	O15118-1.2	E894M	Pathogenic	0.667
NPC1	O15118-1.2	E894N	Pathogenic	0.627
NPC1	O15118-1.2	E894P	Pathogenic	0.623
NPC1	O15118-1.2	E894Q	Neutral	0.394
NPC1	O15118-1.2	E894R	Pathogenic	0.638
NPC1	O15118-1.2	E894S	Pathogenic	0.615
NPC1	O15118-1.2	E894T	Pathogenic	0.654
NPC1	O15118-1.2	E894V	Pathogenic	0.653
NPC1	O15118-1.2	E894W	Pathogenic	0.726
NPC1	O15118-1.2	E894Y	Pathogenic	0.708
NPC1	O15118-1.2	E895A	Pathogenic	0.592
NPC1	O15118-1.2	E895C	Pathogenic	0.767
NPC1	O15118-1.2	E895D	Neutral	0.341
NPC1	O15118-1.2	E895F	Pathogenic	0.635
NPC1	O15118-1.2	E895G	Pathogenic	0.726
NPC1	O15118-1.2	E895H	Neutral	0.461
NPC1	O15118-1.2	E895I	Pathogenic	0.618
NPC1	O15118-1.2	E895K	Neutral	0.426
NPC1	O15118-1.2	E895L	Pathogenic	0.626
NPC1	O15118-1.2	E895M	Pathogenic	0.571
NPC1	O15118-1.2	E895N	Pathogenic	0.528
NPC1	O15118-1.2	E895P	Pathogenic	0.524
NPC1	O15118-1.2	E895Q	Neutral	0.303
NPC1	O15118-1.2	E895R	Pathogenic	0.54
NPC1	O15118-1.2	E895S	Pathogenic	0.516
NPC1	O15118-1.2	E895T	Pathogenic	0.558
NPC1	O15118-1.2	E895V	Pathogenic	0.556
NPC1	O15118-1.2	E895W	Pathogenic	0.639
NPC1	O15118-1.2	E895Y	Pathogenic	0.618
NPC1	O15118-1.2	G896A	Pathogenic	0.858
NPC1	O15118-1.2	G896C	Pathogenic	0.945
NPC1	O15118-1.2	G896D	Pathogenic	0.898
NPC1	O15118-1.2	G896E	Pathogenic	0.938
NPC1	O15118-1.2	G896F	Pathogenic	0.946
NPC1	O15118-1.2	G896H	Pathogenic	0.95
NPC1	O15118-1.2	G896I	Pathogenic	0.96
NPC1	O15118-1.2	G896K	Pathogenic	0.94
NPC1	O15118-1.2	G896L	Pathogenic	0.962
NPC1	O15118-1.2	G896M	Pathogenic	0.952
NPC1	O15118-1.2	G896N	Pathogenic	0.867
NPC1	O15118-1.2	G896P	Pathogenic	0.929
NPC1	O15118-1.2	G896Q	Pathogenic	0.947
NPC1	O15118-1.2	G896R	Pathogenic	0.944
NPC1	O15118-1.2	G896S	Pathogenic	0.872
NPC1	O15118-1.2	G896T	Pathogenic	0.939
NPC1	O15118-1.2	G896V	Pathogenic	0.947
NPC1	O15118-1.2	G896W	Pathogenic	0.924
NPC1	O15118-1.2	G896Y	Pathogenic	0.96
NPC1	O15118-1.2	H897A	Pathogenic	0.823
NPC1	O15118-1.2	H897C	Pathogenic	0.829
NPC1	O15118-1.2	H897D	Pathogenic	0.682
NPC1	O15118-1.2	H897E	Pathogenic	0.577
NPC1	O15118-1.2	H897F	Pathogenic	0.611
NPC1	O15118-1.2	H897G	Pathogenic	0.841
NPC1	O15118-1.2	H897I	Pathogenic	0.76
NPC1	O15118-1.2	H897K	Pathogenic	0.652
NPC1	O15118-1.2	H897L	Pathogenic	0.766
NPC1	O15118-1.2	H897M	Pathogenic	0.722
NPC1	O15118-1.2	H897N	Pathogenic	0.504
NPC1	O15118-1.2	H897P	Pathogenic	0.779
NPC1	O15118-1.2	H897Q	Pathogenic	0.604
NPC1	O15118-1.2	H897R	Pathogenic	0.579
NPC1	O15118-1.2	H897S	Pathogenic	0.753
NPC1	O15118-1.2	H897T	Pathogenic	0.801
NPC1	O15118-1.2	H897V	Pathogenic	0.8
NPC1	O15118-1.2	H897W	Pathogenic	0.701
NPC1	O15118-1.2	H897Y	Neutral	0.403
NPC1	O15118-1.2	D898A	Pathogenic	0.834
NPC1	O15118-1.2	D898C	Pathogenic	0.841
NPC1	O15118-1.2	D898E	Pathogenic	0.587
NPC1	O15118-1.2	D898F	Pathogenic	0.836
NPC1	O15118-1.2	D898G	Pathogenic	0.81
NPC1	O15118-1.2	D898H	Pathogenic	0.787
NPC1	O15118-1.2	D898I	Pathogenic	0.826
NPC1	O15118-1.2	D898K	Pathogenic	0.837
NPC1	O15118-1.2	D898L	Pathogenic	0.879
NPC1	O15118-1.2	D898M	Pathogenic	0.852
NPC1	O15118-1.2	D898N	Pathogenic	0.656
NPC1	O15118-1.2	D898P	Pathogenic	0.722
NPC1	O15118-1.2	D898Q	Pathogenic	0.734
NPC1	O15118-1.2	D898R	Pathogenic	0.891
NPC1	O15118-1.2	D898S	Pathogenic	0.716
NPC1	O15118-1.2	D898T	Pathogenic	0.753
NPC1	O15118-1.2	D898V	Pathogenic	0.838
NPC1	O15118-1.2	D898W	Pathogenic	0.884
NPC1	O15118-1.2	D898Y	Pathogenic	0.875
NPC1	O15118-1.2	Y899A	Pathogenic	0.948
NPC1	O15118-1.2	Y899C	Pathogenic	0.952
NPC1	O15118-1.2	Y899D	Pathogenic	0.942
NPC1	O15118-1.2	Y899E	Pathogenic	0.912
NPC1	O15118-1.2	Y899F	Pathogenic	0.623
NPC1	O15118-1.2	Y899G	Pathogenic	0.964
NPC1	O15118-1.2	Y899H	Pathogenic	0.729
NPC1	O15118-1.2	Y899I	Pathogenic	0.892
NPC1	O15118-1.2	Y899K	Pathogenic	0.887
NPC1	O15118-1.2	Y899L	Pathogenic	0.895
NPC1	O15118-1.2	Y899M	Pathogenic	0.909
NPC1	O15118-1.2	Y899N	Pathogenic	0.919
NPC1	O15118-1.2	Y899P	Pathogenic	0.964
NPC1	O15118-1.2	Y899Q	Pathogenic	0.887
NPC1	O15118-1.2	Y899R	Pathogenic	0.887
NPC1	O15118-1.2	Y899S	Pathogenic	0.94
NPC1	O15118-1.2	Y899T	Pathogenic	0.939
NPC1	O15118-1.2	Y899V	Pathogenic	0.918
NPC1	O15118-1.2	Y899W	Pathogenic	0.697
NPC1	O15118-1.2	T900A	Pathogenic	0.652
NPC1	O15118-1.2	T900C	Pathogenic	0.662
NPC1	O15118-1.2	T900D	Pathogenic	0.632
NPC1	O15118-1.2	T900E	Pathogenic	0.662
NPC1	O15118-1.2	T900F	Pathogenic	0.732
NPC1	O15118-1.2	T900G	Pathogenic	0.809
NPC1	O15118-1.2	T900H	Pathogenic	0.797
NPC1	O15118-1.2	T900I	Pathogenic	0.633
NPC1	O15118-1.2	T900K	Pathogenic	0.671
NPC1	O15118-1.2	T900L	Pathogenic	0.641
NPC1	O15118-1.2	T900M	Pathogenic	0.676
NPC1	O15118-1.2	T900N	Pathogenic	0.555
NPC1	O15118-1.2	T900P	Pathogenic	0.676
NPC1	O15118-1.2	T900Q	Pathogenic	0.699
NPC1	O15118-1.2	T900R	Pathogenic	0.687
NPC1	O15118-1.2	T900S	Pathogenic	0.531
NPC1	O15118-1.2	T900V	Pathogenic	0.56
NPC1	O15118-1.2	T900W	Pathogenic	0.735
NPC1	O15118-1.2	T900Y	Pathogenic	0.788
NPC1	O15118-1.2	S901A	Neutral	0.271
NPC1	O15118-1.2	S901C	Neutral	0.401
NPC1	O15118-1.2	S901D	Neutral	0.34
NPC1	O15118-1.2	S901E	Neutral	0.375
NPC1	O15118-1.2	S901F	Pathogenic	0.503
NPC1	O15118-1.2	S901G	Neutral	0.404
NPC1	O15118-1.2	S901H	Pathogenic	0.519
NPC1	O15118-1.2	S901I	Neutral	0.485
NPC1	O15118-1.2	S901K	Neutral	0.385
NPC1	O15118-1.2	S901L	Neutral	0.494
NPC1	O15118-1.2	S901M	Neutral	0.437
NPC1	O15118-1.2	S901N	Neutral	0.276
NPC1	O15118-1.2	S901P	Neutral	0.428
NPC1	O15118-1.2	S901Q	Neutral	0.416
NPC1	O15118-1.2	S901R	Neutral	0.498
NPC1	O15118-1.2	S901T	Neutral	0.291
NPC1	O15118-1.2	S901V	Pathogenic	0.505
NPC1	O15118-1.2	S901W	Pathogenic	0.602
NPC1	O15118-1.2	S901Y	Pathogenic	0.58
NPC1	O15118-1.2	S902A	Neutral	0.039
NPC1	O15118-1.2	S902C	Neutral	0.069
NPC1	O15118-1.2	S902D	Neutral	0.054
NPC1	O15118-1.2	S902E	Neutral	0.062
NPC1	O15118-1.2	S902F	Neutral	0.101
NPC1	O15118-1.2	S902G	Neutral	0.07
NPC1	O15118-1.2	S902H	Neutral	0.106
NPC1	O15118-1.2	S902I	Neutral	0.094
NPC1	O15118-1.2	S902K	Neutral	0.065
NPC1	O15118-1.2	S902L	Neutral	0.097
NPC1	O15118-1.2	S902M	Neutral	0.079
NPC1	O15118-1.2	S902N	Neutral	0.041
NPC1	O15118-1.2	S902P	Neutral	0.076
NPC1	O15118-1.2	S902Q	Neutral	0.073
NPC1	O15118-1.2	S902R	Neutral	0.099
NPC1	O15118-1.2	S902T	Neutral	0.043
NPC1	O15118-1.2	S902V	Neutral	0.101
NPC1	O15118-1.2	S902W	Neutral	0.143
NPC1	O15118-1.2	S902Y	Neutral	0.133
NPC1	O15118-1.2	K903A	Neutral	0.231
NPC1	O15118-1.2	K903C	Neutral	0.317
NPC1	O15118-1.2	K903D	Neutral	0.272
NPC1	O15118-1.2	K903E	Neutral	0.129
NPC1	O15118-1.2	K903F	Neutral	0.209
NPC1	O15118-1.2	K903G	Neutral	0.355
NPC1	O15118-1.2	K903H	Neutral	0.19
NPC1	O15118-1.2	K903I	Neutral	0.219
NPC1	O15118-1.2	K903L	Neutral	0.165
NPC1	O15118-1.2	K903M	Neutral	0.136
NPC1	O15118-1.2	K903N	Neutral	0.189
NPC1	O15118-1.2	K903P	Neutral	0.186
NPC1	O15118-1.2	K903Q	Neutral	0.111
NPC1	O15118-1.2	K903R	Neutral	0.094
NPC1	O15118-1.2	K903S	Neutral	0.181
NPC1	O15118-1.2	K903T	Neutral	0.207
NPC1	O15118-1.2	K903V	Neutral	0.207
NPC1	O15118-1.2	K903W	Neutral	0.211
NPC1	O15118-1.2	K903Y	Neutral	0.197
NPC1	O15118-1.2	G904A	Neutral	0.483
NPC1	O15118-1.2	G904C	Pathogenic	0.727
NPC1	O15118-1.2	G904D	Pathogenic	0.577
NPC1	O15118-1.2	G904E	Pathogenic	0.7
NPC1	O15118-1.2	G904F	Pathogenic	0.733
NPC1	O15118-1.2	G904H	Pathogenic	0.745
NPC1	O15118-1.2	G904I	Pathogenic	0.79
NPC1	O15118-1.2	G904K	Pathogenic	0.708
NPC1	O15118-1.2	G904L	Pathogenic	0.795
NPC1	O15118-1.2	G904M	Pathogenic	0.755
NPC1	O15118-1.2	G904N	Pathogenic	0.502
NPC1	O15118-1.2	G904P	Pathogenic	0.669
NPC1	O15118-1.2	G904Q	Pathogenic	0.734
NPC1	O15118-1.2	G904R	Pathogenic	0.723
NPC1	O15118-1.2	G904S	Pathogenic	0.514
NPC1	O15118-1.2	G904T	Pathogenic	0.706
NPC1	O15118-1.2	G904V	Pathogenic	0.734
NPC1	O15118-1.2	G904W	Pathogenic	0.654
NPC1	O15118-1.2	G904Y	Pathogenic	0.789
NPC1	O15118-1.2	Q905A	Pathogenic	0.93
NPC1	O15118-1.2	Q905C	Pathogenic	0.954
NPC1	O15118-1.2	Q905D	Pathogenic	0.886
NPC1	O15118-1.2	Q905E	Pathogenic	0.772
NPC1	O15118-1.2	Q905F	Pathogenic	0.938
NPC1	O15118-1.2	Q905G	Pathogenic	0.961
NPC1	O15118-1.2	Q905H	Pathogenic	0.881
NPC1	O15118-1.2	Q905I	Pathogenic	0.934
NPC1	O15118-1.2	Q905K	Pathogenic	0.83
NPC1	O15118-1.2	Q905L	Pathogenic	0.908
NPC1	O15118-1.2	Q905M	Pathogenic	0.842
NPC1	O15118-1.2	Q905N	Pathogenic	0.889
NPC1	O15118-1.2	Q905P	Pathogenic	0.91
NPC1	O15118-1.2	Q905R	Pathogenic	0.84
NPC1	O15118-1.2	Q905S	Pathogenic	0.908
NPC1	O15118-1.2	Q905T	Pathogenic	0.921
NPC1	O15118-1.2	Q905V	Pathogenic	0.92
NPC1	O15118-1.2	Q905W	Pathogenic	0.913
NPC1	O15118-1.2	Q905Y	Pathogenic	0.905
NPC1	O15118-1.2	N906A	Pathogenic	0.925
NPC1	O15118-1.2	N906C	Pathogenic	0.928
NPC1	O15118-1.2	N906D	Pathogenic	0.811
NPC1	O15118-1.2	N906E	Pathogenic	0.873
NPC1	O15118-1.2	N906F	Pathogenic	0.922
NPC1	O15118-1.2	N906G	Pathogenic	0.876
NPC1	O15118-1.2	N906H	Pathogenic	0.797
NPC1	O15118-1.2	N906I	Pathogenic	0.916
NPC1	O15118-1.2	N906K	Pathogenic	0.878
NPC1	O15118-1.2	N906L	Pathogenic	0.919
NPC1	O15118-1.2	N906M	Pathogenic	0.9
NPC1	O15118-1.2	N906P	Pathogenic	0.903
NPC1	O15118-1.2	N906Q	Pathogenic	0.864
NPC1	O15118-1.2	N906R	Pathogenic	0.886
NPC1	O15118-1.2	N906S	Pathogenic	0.807
NPC1	O15118-1.2	N906T	Pathogenic	0.832
NPC1	O15118-1.2	N906V	Pathogenic	0.922
NPC1	O15118-1.2	N906W	Pathogenic	0.946
NPC1	O15118-1.2	N906Y	Pathogenic	0.916
NPC1	O15118-1.2	M907A	Pathogenic	0.509
NPC1	O15118-1.2	M907C	Pathogenic	0.536
NPC1	O15118-1.2	M907D	Pathogenic	0.576
NPC1	O15118-1.2	M907E	Neutral	0.464
NPC1	O15118-1.2	M907F	Neutral	0.376
NPC1	O15118-1.2	M907G	Pathogenic	0.694
NPC1	O15118-1.2	M907H	Pathogenic	0.514
NPC1	O15118-1.2	M907I	Neutral	0.276
NPC1	O15118-1.2	M907K	Neutral	0.338
NPC1	O15118-1.2	M907L	Neutral	0.212
NPC1	O15118-1.2	M907N	Neutral	0.486
NPC1	O15118-1.2	M907P	Pathogenic	0.603
NPC1	O15118-1.2	M907Q	Neutral	0.308
NPC1	O15118-1.2	M907R	Neutral	0.354
NPC1	O15118-1.2	M907S	Neutral	0.471
NPC1	O15118-1.2	M907T	Neutral	0.466
NPC1	O15118-1.2	M907V	Neutral	0.34
NPC1	O15118-1.2	M907W	Neutral	0.474
NPC1	O15118-1.2	M907Y	Pathogenic	0.503
NPC1	O15118-1.2	V908A	Pathogenic	0.748
NPC1	O15118-1.2	V908C	Pathogenic	0.829
NPC1	O15118-1.2	V908D	Pathogenic	0.851
NPC1	O15118-1.2	V908E	Pathogenic	0.792
NPC1	O15118-1.2	V908F	Pathogenic	0.823
NPC1	O15118-1.2	V908G	Pathogenic	0.905
NPC1	O15118-1.2	V908H	Pathogenic	0.884
NPC1	O15118-1.2	V908I	Neutral	0.48
NPC1	O15118-1.2	V908K	Pathogenic	0.799
NPC1	O15118-1.2	V908L	Pathogenic	0.674
NPC1	O15118-1.2	V908M	Pathogenic	0.707
NPC1	O15118-1.2	V908N	Pathogenic	0.854
NPC1	O15118-1.2	V908P	Pathogenic	0.865
NPC1	O15118-1.2	V908Q	Pathogenic	0.819
NPC1	O15118-1.2	V908R	Pathogenic	0.863
NPC1	O15118-1.2	V908S	Pathogenic	0.846
NPC1	O15118-1.2	V908T	Pathogenic	0.713
NPC1	O15118-1.2	V908W	Pathogenic	0.911
NPC1	O15118-1.2	V908Y	Pathogenic	0.842
NPC1	O15118-1.2	C909A	Pathogenic	0.95
NPC1	O15118-1.2	C909D	Pathogenic	0.975
NPC1	O15118-1.2	C909E	Pathogenic	0.985
NPC1	O15118-1.2	C909F	Pathogenic	0.979
NPC1	O15118-1.2	C909G	Pathogenic	0.984
NPC1	O15118-1.2	C909H	Pathogenic	0.984
NPC1	O15118-1.2	C909I	Pathogenic	0.968
NPC1	O15118-1.2	C909K	Pathogenic	0.979
NPC1	O15118-1.2	C909L	Pathogenic	0.969
NPC1	O15118-1.2	C909M	Pathogenic	0.973
NPC1	O15118-1.2	C909N	Pathogenic	0.977
NPC1	O15118-1.2	C909P	Pathogenic	0.985
NPC1	O15118-1.2	C909Q	Pathogenic	0.982
NPC1	O15118-1.2	C909R	Pathogenic	0.981
NPC1	O15118-1.2	C909S	Pathogenic	0.96
NPC1	O15118-1.2	C909T	Pathogenic	0.963
NPC1	O15118-1.2	C909V	Pathogenic	0.97
NPC1	O15118-1.2	C909W	Pathogenic	0.98
NPC1	O15118-1.2	C909Y	Pathogenic	0.985
NPC1	O15118-1.2	G910A	Pathogenic	0.842
NPC1	O15118-1.2	G910C	Pathogenic	0.938
NPC1	O15118-1.2	G910D	Pathogenic	0.886
NPC1	O15118-1.2	G910E	Pathogenic	0.93
NPC1	O15118-1.2	G910F	Pathogenic	0.94
NPC1	O15118-1.2	G910H	Pathogenic	0.943
NPC1	O15118-1.2	G910I	Pathogenic	0.955
NPC1	O15118-1.2	G910K	Pathogenic	0.933
NPC1	O15118-1.2	G910L	Pathogenic	0.957
NPC1	O15118-1.2	G910M	Pathogenic	0.946
NPC1	O15118-1.2	G910N	Pathogenic	0.852
NPC1	O15118-1.2	G910P	Pathogenic	0.92
NPC1	O15118-1.2	G910Q	Pathogenic	0.94
NPC1	O15118-1.2	G910R	Pathogenic	0.937
NPC1	O15118-1.2	G910S	Pathogenic	0.858
NPC1	O15118-1.2	G910T	Pathogenic	0.932
NPC1	O15118-1.2	G910V	Pathogenic	0.94
NPC1	O15118-1.2	G910W	Pathogenic	0.915
NPC1	O15118-1.2	G910Y	Pathogenic	0.955
NPC1	O15118-1.2	G911A	Pathogenic	0.857
NPC1	O15118-1.2	G911C	Pathogenic	0.945
NPC1	O15118-1.2	G911D	Pathogenic	0.898
NPC1	O15118-1.2	G911E	Pathogenic	0.938
NPC1	O15118-1.2	G911F	Pathogenic	0.946
NPC1	O15118-1.2	G911H	Pathogenic	0.949
NPC1	O15118-1.2	G911I	Pathogenic	0.96
NPC1	O15118-1.2	G911K	Pathogenic	0.94
NPC1	O15118-1.2	G911L	Pathogenic	0.962
NPC1	O15118-1.2	G911M	Pathogenic	0.952
NPC1	O15118-1.2	G911N	Pathogenic	0.867
NPC1	O15118-1.2	G911P	Pathogenic	0.929
NPC1	O15118-1.2	G911Q	Pathogenic	0.947
NPC1	O15118-1.2	G911R	Pathogenic	0.944
NPC1	O15118-1.2	G911S	Pathogenic	0.872
NPC1	O15118-1.2	G911T	Pathogenic	0.939
NPC1	O15118-1.2	G911V	Pathogenic	0.947
NPC1	O15118-1.2	G911W	Pathogenic	0.924
NPC1	O15118-1.2	G911Y	Pathogenic	0.96
NPC1	O15118-1.2	M912A	Neutral	0.346
NPC1	O15118-1.2	M912C	Neutral	0.371
NPC1	O15118-1.2	M912D	Neutral	0.409
NPC1	O15118-1.2	M912E	Neutral	0.306
NPC1	O15118-1.2	M912F	Neutral	0.235
NPC1	O15118-1.2	M912G	Pathogenic	0.537
NPC1	O15118-1.2	M912H	Neutral	0.351
NPC1	O15118-1.2	M912I	Neutral	0.163
NPC1	O15118-1.2	M912K	Neutral	0.207
NPC1	O15118-1.2	M912L	Neutral	0.121
NPC1	O15118-1.2	M912N	Neutral	0.326
NPC1	O15118-1.2	M912P	Neutral	0.437
NPC1	O15118-1.2	M912Q	Neutral	0.185
NPC1	O15118-1.2	M912R	Neutral	0.219
NPC1	O15118-1.2	M912S	Neutral	0.313
NPC1	O15118-1.2	M912T	Neutral	0.308
NPC1	O15118-1.2	M912V	Neutral	0.208
NPC1	O15118-1.2	M912W	Neutral	0.315
NPC1	O15118-1.2	M912Y	Neutral	0.341
NPC1	O15118-1.2	G913A	Pathogenic	0.774
NPC1	O15118-1.2	G913C	Pathogenic	0.907
NPC1	O15118-1.2	G913D	Pathogenic	0.833
NPC1	O15118-1.2	G913E	Pathogenic	0.896
NPC1	O15118-1.2	G913F	Pathogenic	0.91
NPC1	O15118-1.2	G913H	Pathogenic	0.915
NPC1	O15118-1.2	G913I	Pathogenic	0.932
NPC1	O15118-1.2	G913K	Pathogenic	0.899
NPC1	O15118-1.2	G913L	Pathogenic	0.935
NPC1	O15118-1.2	G913M	Pathogenic	0.919
NPC1	O15118-1.2	G913N	Pathogenic	0.788
NPC1	O15118-1.2	G913P	Pathogenic	0.882
NPC1	O15118-1.2	G913Q	Pathogenic	0.91
NPC1	O15118-1.2	G913R	Pathogenic	0.906
NPC1	O15118-1.2	G913S	Pathogenic	0.796
NPC1	O15118-1.2	G913T	Pathogenic	0.898
NPC1	O15118-1.2	G913V	Pathogenic	0.91
NPC1	O15118-1.2	G913W	Pathogenic	0.874
NPC1	O15118-1.2	G913Y	Pathogenic	0.932
NPC1	O15118-1.2	C914A	Pathogenic	0.95
NPC1	O15118-1.2	C914D	Pathogenic	0.975
NPC1	O15118-1.2	C914E	Pathogenic	0.985
NPC1	O15118-1.2	C914F	Pathogenic	0.979
NPC1	O15118-1.2	C914G	Pathogenic	0.984
NPC1	O15118-1.2	C914H	Pathogenic	0.984
NPC1	O15118-1.2	C914I	Pathogenic	0.968
NPC1	O15118-1.2	C914K	Pathogenic	0.979
NPC1	O15118-1.2	C914L	Pathogenic	0.969
NPC1	O15118-1.2	C914M	Pathogenic	0.973
NPC1	O15118-1.2	C914N	Pathogenic	0.977
NPC1	O15118-1.2	C914P	Pathogenic	0.985
NPC1	O15118-1.2	C914Q	Pathogenic	0.982
NPC1	O15118-1.2	C914R	Pathogenic	0.981
NPC1	O15118-1.2	C914S	Pathogenic	0.96
NPC1	O15118-1.2	C914T	Pathogenic	0.963
NPC1	O15118-1.2	C914V	Pathogenic	0.97
NPC1	O15118-1.2	C914W	Pathogenic	0.98
NPC1	O15118-1.2	C914Y	Pathogenic	0.985
NPC1	O15118-1.2	N915A	Pathogenic	0.828
NPC1	O15118-1.2	N915C	Pathogenic	0.834
NPC1	O15118-1.2	N915D	Pathogenic	0.625
NPC1	O15118-1.2	N915E	Pathogenic	0.729
NPC1	O15118-1.2	N915F	Pathogenic	0.821
NPC1	O15118-1.2	N915G	Pathogenic	0.734
NPC1	O15118-1.2	N915H	Pathogenic	0.605
NPC1	O15118-1.2	N915I	Pathogenic	0.81
NPC1	O15118-1.2	N915K	Pathogenic	0.737
NPC1	O15118-1.2	N915L	Pathogenic	0.815
NPC1	O15118-1.2	N915M	Pathogenic	0.778
NPC1	O15118-1.2	N915P	Pathogenic	0.785
NPC1	O15118-1.2	N915Q	Pathogenic	0.712
NPC1	O15118-1.2	N915R	Pathogenic	0.751
NPC1	O15118-1.2	N915S	Pathogenic	0.62
NPC1	O15118-1.2	N915T	Pathogenic	0.659
NPC1	O15118-1.2	N915V	Pathogenic	0.822
NPC1	O15118-1.2	N915W	Pathogenic	0.873
NPC1	O15118-1.2	N915Y	Pathogenic	0.81
NPC1	O15118-1.2	N916A	Pathogenic	0.548
NPC1	O15118-1.2	N916C	Pathogenic	0.56
NPC1	O15118-1.2	N916D	Neutral	0.297
NPC1	O15118-1.2	N916E	Neutral	0.405
NPC1	O15118-1.2	N916F	Pathogenic	0.537
NPC1	O15118-1.2	N916G	Neutral	0.411
NPC1	O15118-1.2	N916H	Neutral	0.279
NPC1	O15118-1.2	N916I	Pathogenic	0.519
NPC1	O15118-1.2	N916K	Neutral	0.415
NPC1	O15118-1.2	N916L	Pathogenic	0.527
NPC1	O15118-1.2	N916M	Neutral	0.47
NPC1	O15118-1.2	N916P	Neutral	0.479
NPC1	O15118-1.2	N916Q	Neutral	0.385
NPC1	O15118-1.2	N916R	Neutral	0.433
NPC1	O15118-1.2	N916S	Neutral	0.292
NPC1	O15118-1.2	N916T	Neutral	0.328
NPC1	O15118-1.2	N916V	Pathogenic	0.539
NPC1	O15118-1.2	N916W	Pathogenic	0.634
NPC1	O15118-1.2	N916Y	Pathogenic	0.518
NPC1	O15118-1.2	D917A	Pathogenic	0.821
NPC1	O15118-1.2	D917C	Pathogenic	0.828
NPC1	O15118-1.2	D917E	Pathogenic	0.565
NPC1	O15118-1.2	D917F	Pathogenic	0.824
NPC1	O15118-1.2	D917G	Pathogenic	0.795
NPC1	O15118-1.2	D917H	Pathogenic	0.772
NPC1	O15118-1.2	D917I	Pathogenic	0.813
NPC1	O15118-1.2	D917K	Pathogenic	0.824
NPC1	O15118-1.2	D917L	Pathogenic	0.869
NPC1	O15118-1.2	D917M	Pathogenic	0.84
NPC1	O15118-1.2	D917N	Pathogenic	0.635
NPC1	O15118-1.2	D917P	Pathogenic	0.704
NPC1	O15118-1.2	D917Q	Pathogenic	0.716
NPC1	O15118-1.2	D917R	Pathogenic	0.881
NPC1	O15118-1.2	D917S	Pathogenic	0.697
NPC1	O15118-1.2	D917T	Pathogenic	0.736
NPC1	O15118-1.2	D917V	Pathogenic	0.825
NPC1	O15118-1.2	D917W	Pathogenic	0.875
NPC1	O15118-1.2	D917Y	Pathogenic	0.864
NPC1	O15118-1.2	S918A	Pathogenic	0.904
NPC1	O15118-1.2	S918C	Pathogenic	0.944
NPC1	O15118-1.2	S918D	Pathogenic	0.929
NPC1	O15118-1.2	S918E	Pathogenic	0.939
NPC1	O15118-1.2	S918F	Pathogenic	0.963
NPC1	O15118-1.2	S918G	Pathogenic	0.945
NPC1	O15118-1.2	S918H	Pathogenic	0.965
NPC1	O15118-1.2	S918I	Pathogenic	0.96
NPC1	O15118-1.2	S918K	Pathogenic	0.941
NPC1	O15118-1.2	S918L	Pathogenic	0.961
NPC1	O15118-1.2	S918M	Pathogenic	0.952
NPC1	O15118-1.2	S918N	Pathogenic	0.907
NPC1	O15118-1.2	S918P	Pathogenic	0.95
NPC1	O15118-1.2	S918Q	Pathogenic	0.948
NPC1	O15118-1.2	S918R	Pathogenic	0.962
NPC1	O15118-1.2	S918T	Pathogenic	0.913
NPC1	O15118-1.2	S918V	Pathogenic	0.963
NPC1	O15118-1.2	S918W	Pathogenic	0.975
NPC1	O15118-1.2	S918Y	Pathogenic	0.972
NPC1	O15118-1.2	L919A	Pathogenic	0.858
NPC1	O15118-1.2	L919C	Pathogenic	0.871
NPC1	O15118-1.2	L919D	Pathogenic	0.921
NPC1	O15118-1.2	L919E	Pathogenic	0.881
NPC1	O15118-1.2	L919F	Pathogenic	0.828
NPC1	O15118-1.2	L919G	Pathogenic	0.951
NPC1	O15118-1.2	L919H	Pathogenic	0.901
NPC1	O15118-1.2	L919I	Pathogenic	0.674
NPC1	O15118-1.2	L919K	Pathogenic	0.814
NPC1	O15118-1.2	L919M	Pathogenic	0.646
NPC1	O15118-1.2	L919N	Pathogenic	0.89
NPC1	O15118-1.2	L919P	Pathogenic	0.929
NPC1	O15118-1.2	L919Q	Pathogenic	0.849
NPC1	O15118-1.2	L919R	Pathogenic	0.825
NPC1	O15118-1.2	L919S	Pathogenic	0.884
NPC1	O15118-1.2	L919T	Pathogenic	0.835
NPC1	O15118-1.2	L919V	Pathogenic	0.75
NPC1	O15118-1.2	L919W	Pathogenic	0.913
NPC1	O15118-1.2	L919Y	Pathogenic	0.855
NPC1	O15118-1.2	V920A	Neutral	0.415
NPC1	O15118-1.2	V920C	Pathogenic	0.538
NPC1	O15118-1.2	V920D	Pathogenic	0.578
NPC1	O15118-1.2	V920E	Neutral	0.478
NPC1	O15118-1.2	V920F	Pathogenic	0.527
NPC1	O15118-1.2	V920G	Pathogenic	0.696
NPC1	O15118-1.2	V920H	Pathogenic	0.647
NPC1	O15118-1.2	V920I	Neutral	0.181
NPC1	O15118-1.2	V920K	Neutral	0.488
NPC1	O15118-1.2	V920L	Neutral	0.332
NPC1	O15118-1.2	V920M	Neutral	0.367
NPC1	O15118-1.2	V920N	Pathogenic	0.584
NPC1	O15118-1.2	V920P	Pathogenic	0.605
NPC1	O15118-1.2	V920Q	Pathogenic	0.52
NPC1	O15118-1.2	V920R	Pathogenic	0.601
NPC1	O15118-1.2	V920S	Pathogenic	0.569
NPC1	O15118-1.2	V920T	Neutral	0.374
NPC1	O15118-1.2	V920W	Pathogenic	0.71
NPC1	O15118-1.2	V920Y	Pathogenic	0.562
NPC1	O15118-1.2	Q921A	Pathogenic	0.768
NPC1	O15118-1.2	Q921C	Pathogenic	0.836
NPC1	O15118-1.2	Q921D	Pathogenic	0.658
NPC1	O15118-1.2	Q921E	Neutral	0.455
NPC1	O15118-1.2	Q921F	Pathogenic	0.789
NPC1	O15118-1.2	Q921G	Pathogenic	0.858
NPC1	O15118-1.2	Q921H	Pathogenic	0.647
NPC1	O15118-1.2	Q921I	Pathogenic	0.776
NPC1	O15118-1.2	Q921K	Pathogenic	0.546
NPC1	O15118-1.2	Q921L	Pathogenic	0.71
NPC1	O15118-1.2	Q921M	Pathogenic	0.569
NPC1	O15118-1.2	Q921N	Pathogenic	0.664
NPC1	O15118-1.2	Q921P	Pathogenic	0.715
NPC1	O15118-1.2	Q921R	Pathogenic	0.564
NPC1	O15118-1.2	Q921S	Pathogenic	0.708
NPC1	O15118-1.2	Q921T	Pathogenic	0.742
NPC1	O15118-1.2	Q921V	Pathogenic	0.74
NPC1	O15118-1.2	Q921W	Pathogenic	0.72
NPC1	O15118-1.2	Q921Y	Pathogenic	0.702
NPC1	O15118-1.2	Q922A	Pathogenic	0.952
NPC1	O15118-1.2	Q922C	Pathogenic	0.968
NPC1	O15118-1.2	Q922D	Pathogenic	0.92
NPC1	O15118-1.2	Q922E	Pathogenic	0.833
NPC1	O15118-1.2	Q922F	Pathogenic	0.957
NPC1	O15118-1.2	Q922G	Pathogenic	0.973
NPC1	O15118-1.2	Q922H	Pathogenic	0.917
NPC1	O15118-1.2	Q922I	Pathogenic	0.954
NPC1	O15118-1.2	Q922K	Pathogenic	0.878
NPC1	O15118-1.2	Q922L	Pathogenic	0.936
NPC1	O15118-1.2	Q922M	Pathogenic	0.888
NPC1	O15118-1.2	Q922N	Pathogenic	0.922
NPC1	O15118-1.2	Q922P	Pathogenic	0.938
NPC1	O15118-1.2	Q922R	Pathogenic	0.886
NPC1	O15118-1.2	Q922S	Pathogenic	0.936
NPC1	O15118-1.2	Q922T	Pathogenic	0.945
NPC1	O15118-1.2	Q922V	Pathogenic	0.945
NPC1	O15118-1.2	Q922W	Pathogenic	0.939
NPC1	O15118-1.2	Q922Y	Pathogenic	0.934
NPC1	O15118-1.2	I923A	Pathogenic	0.794
NPC1	O15118-1.2	I923C	Pathogenic	0.811
NPC1	O15118-1.2	I923D	Pathogenic	0.834
NPC1	O15118-1.2	I923E	Pathogenic	0.825
NPC1	O15118-1.2	I923F	Pathogenic	0.764
NPC1	O15118-1.2	I923G	Pathogenic	0.925
NPC1	O15118-1.2	I923H	Pathogenic	0.852
NPC1	O15118-1.2	I923K	Pathogenic	0.804
NPC1	O15118-1.2	I923L	Pathogenic	0.576
NPC1	O15118-1.2	I923M	Pathogenic	0.631
NPC1	O15118-1.2	I923N	Pathogenic	0.838
NPC1	O15118-1.2	I923P	Pathogenic	0.892
NPC1	O15118-1.2	I923Q	Pathogenic	0.84
NPC1	O15118-1.2	I923R	Pathogenic	0.815
NPC1	O15118-1.2	I923S	Pathogenic	0.829
NPC1	O15118-1.2	I923T	Pathogenic	0.764
NPC1	O15118-1.2	I923V	Neutral	0.469
NPC1	O15118-1.2	I923W	Pathogenic	0.914
NPC1	O15118-1.2	I923Y	Pathogenic	0.789
NPC1	O15118-1.2	F924A	Pathogenic	0.72
NPC1	O15118-1.2	F924C	Pathogenic	0.742
NPC1	O15118-1.2	F924D	Pathogenic	0.696
NPC1	O15118-1.2	F924E	Pathogenic	0.682
NPC1	O15118-1.2	F924G	Pathogenic	0.793
NPC1	O15118-1.2	F924H	Pathogenic	0.548
NPC1	O15118-1.2	F924I	Pathogenic	0.579
NPC1	O15118-1.2	F924K	Pathogenic	0.62
NPC1	O15118-1.2	F924L	Pathogenic	0.573
NPC1	O15118-1.2	F924M	Pathogenic	0.534
NPC1	O15118-1.2	F924N	Pathogenic	0.701
NPC1	O15118-1.2	F924P	Pathogenic	0.847
NPC1	O15118-1.2	F924Q	Pathogenic	0.705
NPC1	O15118-1.2	F924R	Pathogenic	0.637
NPC1	O15118-1.2	F924S	Pathogenic	0.689
NPC1	O15118-1.2	F924T	Pathogenic	0.684
NPC1	O15118-1.2	F924V	Pathogenic	0.653
NPC1	O15118-1.2	F924W	Neutral	0.471
NPC1	O15118-1.2	F924Y	Neutral	0.242
NPC1	O15118-1.2	N925A	Neutral	0.222
NPC1	O15118-1.2	N925C	Neutral	0.23
NPC1	O15118-1.2	N925D	Neutral	0.09
NPC1	O15118-1.2	N925E	Neutral	0.138
NPC1	O15118-1.2	N925F	Neutral	0.214
NPC1	O15118-1.2	N925G	Neutral	0.141
NPC1	O15118-1.2	N925H	Neutral	0.083
NPC1	O15118-1.2	N925I	Neutral	0.202
NPC1	O15118-1.2	N925K	Neutral	0.143
NPC1	O15118-1.2	N925L	Neutral	0.208
NPC1	O15118-1.2	N925M	Neutral	0.172
NPC1	O15118-1.2	N925P	Neutral	0.178
NPC1	O15118-1.2	N925Q	Neutral	0.128
NPC1	O15118-1.2	N925R	Neutral	0.152
NPC1	O15118-1.2	N925S	Neutral	0.088
NPC1	O15118-1.2	N925T	Neutral	0.103
NPC1	O15118-1.2	N925V	Neutral	0.215
NPC1	O15118-1.2	N925W	Neutral	0.289
NPC1	O15118-1.2	N925Y	Neutral	0.202
NPC1	O15118-1.2	A926C	Pathogenic	0.904
NPC1	O15118-1.2	A926D	Pathogenic	0.948
NPC1	O15118-1.2	A926E	Pathogenic	0.935
NPC1	O15118-1.2	A926F	Pathogenic	0.954
NPC1	O15118-1.2	A926G	Pathogenic	0.914
NPC1	O15118-1.2	A926H	Pathogenic	0.967
NPC1	O15118-1.2	A926I	Pathogenic	0.93
NPC1	O15118-1.2	A926K	Pathogenic	0.938
NPC1	O15118-1.2	A926L	Pathogenic	0.932
NPC1	O15118-1.2	A926M	Pathogenic	0.941
NPC1	O15118-1.2	A926N	Pathogenic	0.952
NPC1	O15118-1.2	A926P	Pathogenic	0.939
NPC1	O15118-1.2	A926Q	Pathogenic	0.945
NPC1	O15118-1.2	A926R	Pathogenic	0.942
NPC1	O15118-1.2	A926S	Pathogenic	0.868
NPC1	O15118-1.2	A926T	Pathogenic	0.923
NPC1	O15118-1.2	A926V	Pathogenic	0.907
NPC1	O15118-1.2	A926W	Pathogenic	0.969
NPC1	O15118-1.2	A926Y	Pathogenic	0.966
NPC1	O15118-1.2	A927C	Pathogenic	0.674
NPC1	O15118-1.2	A927D	Pathogenic	0.802
NPC1	O15118-1.2	A927E	Pathogenic	0.762
NPC1	O15118-1.2	A927F	Pathogenic	0.822
NPC1	O15118-1.2	A927G	Pathogenic	0.701
NPC1	O15118-1.2	A927H	Pathogenic	0.865
NPC1	O15118-1.2	A927I	Pathogenic	0.745
NPC1	O15118-1.2	A927K	Pathogenic	0.769
NPC1	O15118-1.2	A927L	Pathogenic	0.751
NPC1	O15118-1.2	A927M	Pathogenic	0.779
NPC1	O15118-1.2	A927N	Pathogenic	0.815
NPC1	O15118-1.2	A927P	Pathogenic	0.773
NPC1	O15118-1.2	A927Q	Pathogenic	0.791
NPC1	O15118-1.2	A927R	Pathogenic	0.782
NPC1	O15118-1.2	A927S	Pathogenic	0.592
NPC1	O15118-1.2	A927T	Pathogenic	0.727
NPC1	O15118-1.2	A927V	Pathogenic	0.683
NPC1	O15118-1.2	A927W	Pathogenic	0.873
NPC1	O15118-1.2	A927Y	Pathogenic	0.863
NPC1	O15118-1.2	Q928A	Neutral	0.463
NPC1	O15118-1.2	Q928C	Pathogenic	0.571
NPC1	O15118-1.2	Q928D	Neutral	0.335
NPC1	O15118-1.2	Q928E	Neutral	0.179
NPC1	O15118-1.2	Q928F	Neutral	0.494
NPC1	O15118-1.2	Q928G	Pathogenic	0.612
NPC1	O15118-1.2	Q928H	Neutral	0.324
NPC1	O15118-1.2	Q928I	Neutral	0.476
NPC1	O15118-1.2	Q928K	Neutral	0.239
NPC1	O15118-1.2	Q928L	Neutral	0.39
NPC1	O15118-1.2	Q928M	Neutral	0.256
NPC1	O15118-1.2	Q928N	Neutral	0.341
NPC1	O15118-1.2	Q928P	Neutral	0.396
NPC1	O15118-1.2	Q928R	Neutral	0.253
NPC1	O15118-1.2	Q928S	Neutral	0.388
NPC1	O15118-1.2	Q928T	Neutral	0.429
NPC1	O15118-1.2	Q928V	Neutral	0.427
NPC1	O15118-1.2	Q928W	Neutral	0.402
NPC1	O15118-1.2	Q928Y	Neutral	0.381
NPC1	O15118-1.2	L929A	Neutral	0.183
NPC1	O15118-1.2	L929C	Neutral	0.2
NPC1	O15118-1.2	L929D	Neutral	0.301
NPC1	O15118-1.2	L929E	Neutral	0.215
NPC1	O15118-1.2	L929F	Neutral	0.151
NPC1	O15118-1.2	L929G	Neutral	0.419
NPC1	O15118-1.2	L929H	Neutral	0.251
NPC1	O15118-1.2	L929I	Neutral	0.071
NPC1	O15118-1.2	L929K	Neutral	0.139
NPC1	O15118-1.2	L929M	Neutral	0.063
NPC1	O15118-1.2	L929N	Neutral	0.231
NPC1	O15118-1.2	L929P	Neutral	0.325
NPC1	O15118-1.2	L929Q	Neutral	0.172
NPC1	O15118-1.2	L929R	Neutral	0.148
NPC1	O15118-1.2	L929S	Neutral	0.22
NPC1	O15118-1.2	L929T	Neutral	0.158
NPC1	O15118-1.2	L929V	Neutral	0.1
NPC1	O15118-1.2	L929W	Neutral	0.281
NPC1	O15118-1.2	L929Y	Neutral	0.179
NPC1	O15118-1.2	D930A	Pathogenic	0.506
NPC1	O15118-1.2	D930C	Pathogenic	0.518
NPC1	O15118-1.2	D930E	Neutral	0.224
NPC1	O15118-1.2	D930F	Pathogenic	0.51
NPC1	O15118-1.2	D930G	Neutral	0.464
NPC1	O15118-1.2	D930H	Neutral	0.43
NPC1	O15118-1.2	D930I	Neutral	0.492
NPC1	O15118-1.2	D930K	Pathogenic	0.511
NPC1	O15118-1.2	D930L	Pathogenic	0.596
NPC1	O15118-1.2	D930M	Pathogenic	0.54
NPC1	O15118-1.2	D930N	Neutral	0.28
NPC1	O15118-1.2	D930P	Neutral	0.346
NPC1	O15118-1.2	D930Q	Neutral	0.36
NPC1	O15118-1.2	D930R	Pathogenic	0.624
NPC1	O15118-1.2	D930S	Neutral	0.339
NPC1	O15118-1.2	D930T	Neutral	0.383
NPC1	O15118-1.2	D930V	Pathogenic	0.512
NPC1	O15118-1.2	D930W	Pathogenic	0.609
NPC1	O15118-1.2	D930Y	Pathogenic	0.587
NPC1	O15118-1.2	N931A	Pathogenic	0.69
NPC1	O15118-1.2	N931C	Pathogenic	0.7
NPC1	O15118-1.2	N931D	Neutral	0.437
NPC1	O15118-1.2	N931E	Pathogenic	0.556
NPC1	O15118-1.2	N931F	Pathogenic	0.68
NPC1	O15118-1.2	N931G	Pathogenic	0.562
NPC1	O15118-1.2	N931H	Neutral	0.416
NPC1	O15118-1.2	N931I	Pathogenic	0.665
NPC1	O15118-1.2	N931K	Pathogenic	0.565
NPC1	O15118-1.2	N931L	Pathogenic	0.672
NPC1	O15118-1.2	N931M	Pathogenic	0.62
NPC1	O15118-1.2	N931P	Pathogenic	0.629
NPC1	O15118-1.2	N931Q	Pathogenic	0.535
NPC1	O15118-1.2	N931R	Pathogenic	0.584
NPC1	O15118-1.2	N931S	Neutral	0.431
NPC1	O15118-1.2	N931T	Neutral	0.472
NPC1	O15118-1.2	N931V	Pathogenic	0.682
NPC1	O15118-1.2	N931W	Pathogenic	0.761
NPC1	O15118-1.2	N931Y	Pathogenic	0.664
NPC1	O15118-1.2	Y932A	Pathogenic	0.722
NPC1	O15118-1.2	Y932C	Pathogenic	0.741
NPC1	O15118-1.2	Y932D	Pathogenic	0.698
NPC1	O15118-1.2	Y932E	Pathogenic	0.596
NPC1	O15118-1.2	Y932F	Neutral	0.191
NPC1	O15118-1.2	Y932G	Pathogenic	0.795
NPC1	O15118-1.2	Y932H	Neutral	0.278
NPC1	O15118-1.2	Y932I	Pathogenic	0.54
NPC1	O15118-1.2	Y932K	Pathogenic	0.528
NPC1	O15118-1.2	Y932L	Pathogenic	0.549
NPC1	O15118-1.2	Y932M	Pathogenic	0.587
NPC1	O15118-1.2	Y932N	Pathogenic	0.617
NPC1	O15118-1.2	Y932P	Pathogenic	0.792
NPC1	O15118-1.2	Y932Q	Pathogenic	0.528
NPC1	O15118-1.2	Y932R	Pathogenic	0.529
NPC1	O15118-1.2	Y932S	Pathogenic	0.691
NPC1	O15118-1.2	Y932T	Pathogenic	0.686
NPC1	O15118-1.2	Y932V	Pathogenic	0.616
NPC1	O15118-1.2	Y932W	Neutral	0.247
NPC1	O15118-1.2	T933A	Pathogenic	0.854
NPC1	O15118-1.2	T933C	Pathogenic	0.859
NPC1	O15118-1.2	T933D	Pathogenic	0.843
NPC1	O15118-1.2	T933E	Pathogenic	0.859
NPC1	O15118-1.2	T933F	Pathogenic	0.895
NPC1	O15118-1.2	T933G	Pathogenic	0.93
NPC1	O15118-1.2	T933H	Pathogenic	0.924
NPC1	O15118-1.2	T933I	Pathogenic	0.843
NPC1	O15118-1.2	T933K	Pathogenic	0.864
NPC1	O15118-1.2	T933L	Pathogenic	0.848
NPC1	O15118-1.2	T933M	Pathogenic	0.867
NPC1	O15118-1.2	T933N	Pathogenic	0.795
NPC1	O15118-1.2	T933P	Pathogenic	0.867
NPC1	O15118-1.2	T933Q	Pathogenic	0.878
NPC1	O15118-1.2	T933R	Pathogenic	0.872
NPC1	O15118-1.2	T933S	Pathogenic	0.779
NPC1	O15118-1.2	T933V	Pathogenic	0.798
NPC1	O15118-1.2	T933W	Pathogenic	0.896
NPC1	O15118-1.2	T933Y	Pathogenic	0.921
NPC1	O15118-1.2	R934A	Pathogenic	0.671
NPC1	O15118-1.2	R934C	Pathogenic	0.759
NPC1	O15118-1.2	R934D	Pathogenic	0.788
NPC1	O15118-1.2	R934E	Pathogenic	0.595
NPC1	O15118-1.2	R934F	Pathogenic	0.641
NPC1	O15118-1.2	R934G	Pathogenic	0.788
NPC1	O15118-1.2	R934H	Pathogenic	0.519
NPC1	O15118-1.2	R934I	Pathogenic	0.655
NPC1	O15118-1.2	R934K	Neutral	0.395
NPC1	O15118-1.2	R934L	Pathogenic	0.572
NPC1	O15118-1.2	R934M	Pathogenic	0.515
NPC1	O15118-1.2	R934N	Pathogenic	0.611
NPC1	O15118-1.2	R934P	Pathogenic	0.695
NPC1	O15118-1.2	R934Q	Neutral	0.458
NPC1	O15118-1.2	R934S	Pathogenic	0.688
NPC1	O15118-1.2	R934T	Pathogenic	0.639
NPC1	O15118-1.2	R934V	Pathogenic	0.721
NPC1	O15118-1.2	R934W	Pathogenic	0.608
NPC1	O15118-1.2	R934Y	Pathogenic	0.607
NPC1	O15118-1.2	I935A	Pathogenic	0.901
NPC1	O15118-1.2	I935C	Pathogenic	0.91
NPC1	O15118-1.2	I935D	Pathogenic	0.922
NPC1	O15118-1.2	I935E	Pathogenic	0.917
NPC1	O15118-1.2	I935F	Pathogenic	0.884
NPC1	O15118-1.2	I935G	Pathogenic	0.967
NPC1	O15118-1.2	I935H	Pathogenic	0.931
NPC1	O15118-1.2	I935K	Pathogenic	0.906
NPC1	O15118-1.2	I935L	Pathogenic	0.762
NPC1	O15118-1.2	I935M	Pathogenic	0.801
NPC1	O15118-1.2	I935N	Pathogenic	0.924
NPC1	O15118-1.2	I935P	Pathogenic	0.951
NPC1	O15118-1.2	I935Q	Pathogenic	0.925
NPC1	O15118-1.2	I935R	Pathogenic	0.912
NPC1	O15118-1.2	I935S	Pathogenic	0.92
NPC1	O15118-1.2	I935T	Pathogenic	0.884
NPC1	O15118-1.2	I935V	Pathogenic	0.676
NPC1	O15118-1.2	I935W	Pathogenic	0.961
NPC1	O15118-1.2	I935Y	Pathogenic	0.898
NPC1	O15118-1.2	G936A	Pathogenic	0.753
NPC1	O15118-1.2	G936C	Pathogenic	0.897
NPC1	O15118-1.2	G936D	Pathogenic	0.817
NPC1	O15118-1.2	G936E	Pathogenic	0.884
NPC1	O15118-1.2	G936F	Pathogenic	0.9
NPC1	O15118-1.2	G936H	Pathogenic	0.905
NPC1	O15118-1.2	G936I	Pathogenic	0.925
NPC1	O15118-1.2	G936K	Pathogenic	0.888
NPC1	O15118-1.2	G936L	Pathogenic	0.927
NPC1	O15118-1.2	G936M	Pathogenic	0.91
NPC1	O15118-1.2	G936N	Pathogenic	0.768
NPC1	O15118-1.2	G936P	Pathogenic	0.869
NPC1	O15118-1.2	G936Q	Pathogenic	0.9
NPC1	O15118-1.2	G936R	Pathogenic	0.895
NPC1	O15118-1.2	G936S	Pathogenic	0.776
NPC1	O15118-1.2	G936T	Pathogenic	0.887
NPC1	O15118-1.2	G936V	Pathogenic	0.9
NPC1	O15118-1.2	G936W	Pathogenic	0.861
NPC1	O15118-1.2	G936Y	Pathogenic	0.924
NPC1	O15118-1.2	F937A	Neutral	0.286
NPC1	O15118-1.2	F937C	Neutral	0.309
NPC1	O15118-1.2	F937D	Neutral	0.263
NPC1	O15118-1.2	F937E	Neutral	0.251
NPC1	O15118-1.2	F937G	Neutral	0.374
NPC1	O15118-1.2	F937H	Neutral	0.159
NPC1	O15118-1.2	F937I	Neutral	0.176
NPC1	O15118-1.2	F937K	Neutral	0.203
NPC1	O15118-1.2	F937L	Neutral	0.173
NPC1	O15118-1.2	F937M	Neutral	0.152
NPC1	O15118-1.2	F937N	Neutral	0.268
NPC1	O15118-1.2	F937P	Neutral	0.464
NPC1	O15118-1.2	F937Q	Neutral	0.272
NPC1	O15118-1.2	F937R	Neutral	0.215
NPC1	O15118-1.2	F937S	Neutral	0.257
NPC1	O15118-1.2	F937T	Neutral	0.252
NPC1	O15118-1.2	F937V	Neutral	0.227
NPC1	O15118-1.2	F937W	Neutral	0.122
NPC1	O15118-1.2	F937Y	Neutral	0.047
NPC1	O15118-1.2	A938C	Pathogenic	0.58
NPC1	O15118-1.2	A938D	Pathogenic	0.729
NPC1	O15118-1.2	A938E	Pathogenic	0.68
NPC1	O15118-1.2	A938F	Pathogenic	0.754
NPC1	O15118-1.2	A938G	Pathogenic	0.609
NPC1	O15118-1.2	A938H	Pathogenic	0.81
NPC1	O15118-1.2	A938I	Pathogenic	0.66
NPC1	O15118-1.2	A938K	Pathogenic	0.689
NPC1	O15118-1.2	A938L	Pathogenic	0.668
NPC1	O15118-1.2	A938M	Pathogenic	0.701
NPC1	O15118-1.2	A938N	Pathogenic	0.746
NPC1	O15118-1.2	A938P	Pathogenic	0.694
NPC1	O15118-1.2	A938Q	Pathogenic	0.716
NPC1	O15118-1.2	A938R	Pathogenic	0.705
NPC1	O15118-1.2	A938S	Neutral	0.492
NPC1	O15118-1.2	A938T	Pathogenic	0.639
NPC1	O15118-1.2	A938V	Pathogenic	0.589
NPC1	O15118-1.2	A938W	Pathogenic	0.821
NPC1	O15118-1.2	A938Y	Pathogenic	0.807
NPC1	O15118-1.2	P939A	Pathogenic	0.768
NPC1	O15118-1.2	P939C	Pathogenic	0.87
NPC1	O15118-1.2	P939D	Pathogenic	0.669
NPC1	O15118-1.2	P939E	Pathogenic	0.702
NPC1	O15118-1.2	P939F	Pathogenic	0.906
NPC1	O15118-1.2	P939G	Pathogenic	0.831
NPC1	O15118-1.2	P939H	Pathogenic	0.825
NPC1	O15118-1.2	P939I	Pathogenic	0.859
NPC1	O15118-1.2	P939K	Pathogenic	0.71
NPC1	O15118-1.2	P939L	Pathogenic	0.863
NPC1	O15118-1.2	P939M	Pathogenic	0.834
NPC1	O15118-1.2	P939N	Pathogenic	0.764
NPC1	O15118-1.2	P939Q	Pathogenic	0.736
NPC1	O15118-1.2	P939R	Pathogenic	0.795
NPC1	O15118-1.2	P939S	Pathogenic	0.74
NPC1	O15118-1.2	P939T	Pathogenic	0.742
NPC1	O15118-1.2	P939V	Pathogenic	0.818
NPC1	O15118-1.2	P939W	Pathogenic	0.907
NPC1	O15118-1.2	P939Y	Pathogenic	0.9
NPC1	O15118-1.2	S940A	Pathogenic	0.738
NPC1	O15118-1.2	S940C	Pathogenic	0.835
NPC1	O15118-1.2	S940D	Pathogenic	0.796
NPC1	O15118-1.2	S940E	Pathogenic	0.82
NPC1	O15118-1.2	S940F	Pathogenic	0.885
NPC1	O15118-1.2	S940G	Pathogenic	0.837
NPC1	O15118-1.2	S940H	Pathogenic	0.891
NPC1	O15118-1.2	S940I	Pathogenic	0.877
NPC1	O15118-1.2	S940K	Pathogenic	0.826
NPC1	O15118-1.2	S940L	Pathogenic	0.881
NPC1	O15118-1.2	S940M	Pathogenic	0.855
NPC1	O15118-1.2	S940N	Pathogenic	0.743
NPC1	O15118-1.2	S940P	Pathogenic	0.85
NPC1	O15118-1.2	S940Q	Pathogenic	0.844
NPC1	O15118-1.2	S940R	Pathogenic	0.882
NPC1	O15118-1.2	S940T	Pathogenic	0.757
NPC1	O15118-1.2	S940V	Pathogenic	0.886
NPC1	O15118-1.2	S940W	Pathogenic	0.92
NPC1	O15118-1.2	S940Y	Pathogenic	0.913
NPC1	O15118-1.2	S941A	Pathogenic	0.886
NPC1	O15118-1.2	S941C	Pathogenic	0.933
NPC1	O15118-1.2	S941D	Pathogenic	0.915
NPC1	O15118-1.2	S941E	Pathogenic	0.926
NPC1	O15118-1.2	S941F	Pathogenic	0.955
NPC1	O15118-1.2	S941G	Pathogenic	0.934
NPC1	O15118-1.2	S941H	Pathogenic	0.957
NPC1	O15118-1.2	S941I	Pathogenic	0.952
NPC1	O15118-1.2	S941K	Pathogenic	0.929
NPC1	O15118-1.2	S941L	Pathogenic	0.953
NPC1	O15118-1.2	S941M	Pathogenic	0.942
NPC1	O15118-1.2	S941N	Pathogenic	0.889
NPC1	O15118-1.2	S941P	Pathogenic	0.94
NPC1	O15118-1.2	S941Q	Pathogenic	0.937
NPC1	O15118-1.2	S941R	Pathogenic	0.954
NPC1	O15118-1.2	S941T	Pathogenic	0.896
NPC1	O15118-1.2	S941V	Pathogenic	0.955
NPC1	O15118-1.2	S941W	Pathogenic	0.969
NPC1	O15118-1.2	S941Y	Pathogenic	0.967
NPC1	O15118-1.2	W942A	Pathogenic	0.991
NPC1	O15118-1.2	W942C	Pathogenic	0.988
NPC1	O15118-1.2	W942D	Pathogenic	0.99
NPC1	O15118-1.2	W942E	Pathogenic	0.984
NPC1	O15118-1.2	W942F	Pathogenic	0.962
NPC1	O15118-1.2	W942G	Pathogenic	0.987
NPC1	O15118-1.2	W942H	Pathogenic	0.981
NPC1	O15118-1.2	W942I	Pathogenic	0.992
NPC1	O15118-1.2	W942K	Pathogenic	0.979
NPC1	O15118-1.2	W942L	Pathogenic	0.988
NPC1	O15118-1.2	W942M	Pathogenic	0.98
NPC1	O15118-1.2	W942N	Pathogenic	0.99
NPC1	O15118-1.2	W942P	Pathogenic	0.994
NPC1	O15118-1.2	W942Q	Pathogenic	0.979
NPC1	O15118-1.2	W942R	Pathogenic	0.978
NPC1	O15118-1.2	W942S	Pathogenic	0.99
NPC1	O15118-1.2	W942T	Pathogenic	0.984
NPC1	O15118-1.2	W942V	Pathogenic	0.992
NPC1	O15118-1.2	W942Y	Pathogenic	0.927
NPC1	O15118-1.2	I943A	Pathogenic	0.715
NPC1	O15118-1.2	I943C	Pathogenic	0.736
NPC1	O15118-1.2	I943D	Pathogenic	0.766
NPC1	O15118-1.2	I943E	Pathogenic	0.754
NPC1	O15118-1.2	I943F	Pathogenic	0.678
NPC1	O15118-1.2	I943G	Pathogenic	0.89
NPC1	O15118-1.2	I943H	Pathogenic	0.79
NPC1	O15118-1.2	I943K	Pathogenic	0.727
NPC1	O15118-1.2	I943L	Neutral	0.47
NPC1	O15118-1.2	I943M	Pathogenic	0.527
NPC1	O15118-1.2	I943N	Pathogenic	0.771
NPC1	O15118-1.2	I943P	Pathogenic	0.844
NPC1	O15118-1.2	I943Q	Pathogenic	0.774
NPC1	O15118-1.2	I943R	Pathogenic	0.742
NPC1	O15118-1.2	I943S	Pathogenic	0.76
NPC1	O15118-1.2	I943T	Pathogenic	0.678
NPC1	O15118-1.2	I943V	Neutral	0.365
NPC1	O15118-1.2	I943W	Pathogenic	0.873
NPC1	O15118-1.2	I943Y	Pathogenic	0.71
NPC1	O15118-1.2	D944A	Pathogenic	0.971
NPC1	O15118-1.2	D944C	Pathogenic	0.972
NPC1	O15118-1.2	D944E	Pathogenic	0.904
NPC1	O15118-1.2	D944F	Pathogenic	0.971
NPC1	O15118-1.2	D944G	Pathogenic	0.966
NPC1	O15118-1.2	D944H	Pathogenic	0.961
NPC1	O15118-1.2	D944I	Pathogenic	0.969
NPC1	O15118-1.2	D944K	Pathogenic	0.971
NPC1	O15118-1.2	D944L	Pathogenic	0.98
NPC1	O15118-1.2	D944M	Pathogenic	0.974
NPC1	O15118-1.2	D944N	Pathogenic	0.927
NPC1	O15118-1.2	D944P	Pathogenic	0.945
NPC1	O15118-1.2	D944Q	Pathogenic	0.948
NPC1	O15118-1.2	D944R	Pathogenic	0.982
NPC1	O15118-1.2	D944S	Pathogenic	0.943
NPC1	O15118-1.2	D944T	Pathogenic	0.953
NPC1	O15118-1.2	D944V	Pathogenic	0.972
NPC1	O15118-1.2	D944W	Pathogenic	0.981
NPC1	O15118-1.2	D944Y	Pathogenic	0.979
NPC1	O15118-1.2	D945A	Pathogenic	0.968
NPC1	O15118-1.2	D945C	Pathogenic	0.969
NPC1	O15118-1.2	D945E	Pathogenic	0.895
NPC1	O15118-1.2	D945F	Pathogenic	0.968
NPC1	O15118-1.2	D945G	Pathogenic	0.962
NPC1	O15118-1.2	D945H	Pathogenic	0.957
NPC1	O15118-1.2	D945I	Pathogenic	0.966
NPC1	O15118-1.2	D945K	Pathogenic	0.969
NPC1	O15118-1.2	D945L	Pathogenic	0.977
NPC1	O15118-1.2	D945M	Pathogenic	0.972
NPC1	O15118-1.2	D945N	Pathogenic	0.92
NPC1	O15118-1.2	D945P	Pathogenic	0.94
NPC1	O15118-1.2	D945Q	Pathogenic	0.943
NPC1	O15118-1.2	D945R	Pathogenic	0.98
NPC1	O15118-1.2	D945S	Pathogenic	0.938
NPC1	O15118-1.2	D945T	Pathogenic	0.948
NPC1	O15118-1.2	D945V	Pathogenic	0.969
NPC1	O15118-1.2	D945W	Pathogenic	0.979
NPC1	O15118-1.2	D945Y	Pathogenic	0.977
NPC1	O15118-1.2	Y946A	Pathogenic	0.966
NPC1	O15118-1.2	Y946C	Pathogenic	0.969
NPC1	O15118-1.2	Y946D	Pathogenic	0.962
NPC1	O15118-1.2	Y946E	Pathogenic	0.942
NPC1	O15118-1.2	Y946F	Pathogenic	0.721
NPC1	O15118-1.2	Y946G	Pathogenic	0.977
NPC1	O15118-1.2	Y946H	Pathogenic	0.808
NPC1	O15118-1.2	Y946I	Pathogenic	0.928
NPC1	O15118-1.2	Y946K	Pathogenic	0.925
NPC1	O15118-1.2	Y946L	Pathogenic	0.93
NPC1	O15118-1.2	Y946M	Pathogenic	0.94
NPC1	O15118-1.2	Y946N	Pathogenic	0.946
NPC1	O15118-1.2	Y946P	Pathogenic	0.977
NPC1	O15118-1.2	Y946Q	Pathogenic	0.924
NPC1	O15118-1.2	Y946R	Pathogenic	0.925
NPC1	O15118-1.2	Y946S	Pathogenic	0.961
NPC1	O15118-1.2	Y946T	Pathogenic	0.96
NPC1	O15118-1.2	Y946V	Pathogenic	0.946
NPC1	O15118-1.2	Y946W	Pathogenic	0.782
NPC1	O15118-1.2	F947A	Pathogenic	0.82
NPC1	O15118-1.2	F947C	Pathogenic	0.836
NPC1	O15118-1.2	F947D	Pathogenic	0.802
NPC1	O15118-1.2	F947E	Pathogenic	0.792
NPC1	O15118-1.2	F947G	Pathogenic	0.872
NPC1	O15118-1.2	F947H	Pathogenic	0.682
NPC1	O15118-1.2	F947I	Pathogenic	0.708
NPC1	O15118-1.2	F947K	Pathogenic	0.743
NPC1	O15118-1.2	F947L	Pathogenic	0.703
NPC1	O15118-1.2	F947M	Pathogenic	0.67
NPC1	O15118-1.2	F947N	Pathogenic	0.806
NPC1	O15118-1.2	F947P	Pathogenic	0.908
NPC1	O15118-1.2	F947Q	Pathogenic	0.809
NPC1	O15118-1.2	F947R	Pathogenic	0.757
NPC1	O15118-1.2	F947S	Pathogenic	0.797
NPC1	O15118-1.2	F947T	Pathogenic	0.793
NPC1	O15118-1.2	F947V	Pathogenic	0.769
NPC1	O15118-1.2	F947W	Pathogenic	0.612
NPC1	O15118-1.2	F947Y	Neutral	0.361
NPC1	O15118-1.2	D948A	Pathogenic	0.946
NPC1	O15118-1.2	D948C	Pathogenic	0.948
NPC1	O15118-1.2	D948E	Pathogenic	0.832
NPC1	O15118-1.2	D948F	Pathogenic	0.947
NPC1	O15118-1.2	D948G	Pathogenic	0.937
NPC1	O15118-1.2	D948H	Pathogenic	0.928
NPC1	O15118-1.2	D948I	Pathogenic	0.943
NPC1	O15118-1.2	D948K	Pathogenic	0.947
NPC1	O15118-1.2	D948L	Pathogenic	0.962
NPC1	O15118-1.2	D948M	Pathogenic	0.952
NPC1	O15118-1.2	D948N	Pathogenic	0.869
NPC1	O15118-1.2	D948P	Pathogenic	0.9
NPC1	O15118-1.2	D948Q	Pathogenic	0.906
NPC1	O15118-1.2	D948R	Pathogenic	0.966
NPC1	O15118-1.2	D948S	Pathogenic	0.898
NPC1	O15118-1.2	D948T	Pathogenic	0.914
NPC1	O15118-1.2	D948V	Pathogenic	0.947
NPC1	O15118-1.2	D948W	Pathogenic	0.964
NPC1	O15118-1.2	D948Y	Pathogenic	0.96
NPC1	O15118-1.2	W949A	Pathogenic	0.991
NPC1	O15118-1.2	W949C	Pathogenic	0.988
NPC1	O15118-1.2	W949D	Pathogenic	0.99
NPC1	O15118-1.2	W949E	Pathogenic	0.984
NPC1	O15118-1.2	W949F	Pathogenic	0.962
NPC1	O15118-1.2	W949G	Pathogenic	0.987
NPC1	O15118-1.2	W949H	Pathogenic	0.981
NPC1	O15118-1.2	W949I	Pathogenic	0.992
NPC1	O15118-1.2	W949K	Pathogenic	0.979
NPC1	O15118-1.2	W949L	Pathogenic	0.988
NPC1	O15118-1.2	W949M	Pathogenic	0.98
NPC1	O15118-1.2	W949N	Pathogenic	0.99
NPC1	O15118-1.2	W949P	Pathogenic	0.994
NPC1	O15118-1.2	W949Q	Pathogenic	0.979
NPC1	O15118-1.2	W949R	Pathogenic	0.978
NPC1	O15118-1.2	W949S	Pathogenic	0.99
NPC1	O15118-1.2	W949T	Pathogenic	0.984
NPC1	O15118-1.2	W949V	Pathogenic	0.992
NPC1	O15118-1.2	W949Y	Pathogenic	0.927
NPC1	O15118-1.2	V950A	Neutral	0.328
NPC1	O15118-1.2	V950C	Neutral	0.445
NPC1	O15118-1.2	V950D	Neutral	0.484
NPC1	O15118-1.2	V950E	Neutral	0.386
NPC1	O15118-1.2	V950F	Neutral	0.434
NPC1	O15118-1.2	V950G	Pathogenic	0.611
NPC1	O15118-1.2	V950H	Pathogenic	0.558
NPC1	O15118-1.2	V950I	Neutral	0.132
NPC1	O15118-1.2	V950K	Neutral	0.395
NPC1	O15118-1.2	V950L	Neutral	0.254
NPC1	O15118-1.2	V950M	Neutral	0.285
NPC1	O15118-1.2	V950N	Neutral	0.491
NPC1	O15118-1.2	V950P	Pathogenic	0.513
NPC1	O15118-1.2	V950Q	Neutral	0.427
NPC1	O15118-1.2	V950R	Pathogenic	0.509
NPC1	O15118-1.2	V950S	Neutral	0.476
NPC1	O15118-1.2	V950T	Neutral	0.291
NPC1	O15118-1.2	V950W	Pathogenic	0.627
NPC1	O15118-1.2	V950Y	Neutral	0.469
NPC1	O15118-1.2	K951A	Pathogenic	0.501
NPC1	O15118-1.2	K951C	Pathogenic	0.607
NPC1	O15118-1.2	K951D	Pathogenic	0.554
NPC1	O15118-1.2	K951E	Neutral	0.33
NPC1	O15118-1.2	K951F	Neutral	0.468
NPC1	O15118-1.2	K951G	Pathogenic	0.647
NPC1	O15118-1.2	K951H	Neutral	0.439
NPC1	O15118-1.2	K951I	Neutral	0.483
NPC1	O15118-1.2	K951L	Neutral	0.397
NPC1	O15118-1.2	K951M	Neutral	0.343
NPC1	O15118-1.2	K951N	Neutral	0.437
NPC1	O15118-1.2	K951P	Neutral	0.432
NPC1	O15118-1.2	K951Q	Neutral	0.294
NPC1	O15118-1.2	K951R	Neutral	0.257
NPC1	O15118-1.2	K951S	Neutral	0.425
NPC1	O15118-1.2	K951T	Neutral	0.466
NPC1	O15118-1.2	K951V	Neutral	0.464
NPC1	O15118-1.2	K951W	Neutral	0.472
NPC1	O15118-1.2	K951Y	Neutral	0.45
NPC1	O15118-1.2	P952A	Pathogenic	0.734
NPC1	O15118-1.2	P952C	Pathogenic	0.848
NPC1	O15118-1.2	P952D	Pathogenic	0.628
NPC1	O15118-1.2	P952E	Pathogenic	0.663
NPC1	O15118-1.2	P952F	Pathogenic	0.89
NPC1	O15118-1.2	P952G	Pathogenic	0.804
NPC1	O15118-1.2	P952H	Pathogenic	0.798
NPC1	O15118-1.2	P952I	Pathogenic	0.836
NPC1	O15118-1.2	P952K	Pathogenic	0.672
NPC1	O15118-1.2	P952L	Pathogenic	0.841
NPC1	O15118-1.2	P952M	Pathogenic	0.807
NPC1	O15118-1.2	P952N	Pathogenic	0.73
NPC1	O15118-1.2	P952Q	Pathogenic	0.7
NPC1	O15118-1.2	P952R	Pathogenic	0.764
NPC1	O15118-1.2	P952S	Pathogenic	0.704
NPC1	O15118-1.2	P952T	Pathogenic	0.706
NPC1	O15118-1.2	P952V	Pathogenic	0.79
NPC1	O15118-1.2	P952W	Pathogenic	0.891
NPC1	O15118-1.2	P952Y	Pathogenic	0.882
NPC1	O15118-1.2	Q953A	Pathogenic	0.588
NPC1	O15118-1.2	Q953C	Pathogenic	0.688
NPC1	O15118-1.2	Q953D	Neutral	0.455
NPC1	O15118-1.2	Q953E	Neutral	0.265
NPC1	O15118-1.2	Q953F	Pathogenic	0.617
NPC1	O15118-1.2	Q953G	Pathogenic	0.723
NPC1	O15118-1.2	Q953H	Neutral	0.442
NPC1	O15118-1.2	Q953I	Pathogenic	0.6
NPC1	O15118-1.2	Q953K	Neutral	0.342
NPC1	O15118-1.2	Q953L	Pathogenic	0.514
NPC1	O15118-1.2	Q953M	Neutral	0.363
NPC1	O15118-1.2	Q953N	Neutral	0.461
NPC1	O15118-1.2	Q953P	Pathogenic	0.52
NPC1	O15118-1.2	Q953R	Neutral	0.359
NPC1	O15118-1.2	Q953S	Pathogenic	0.512
NPC1	O15118-1.2	Q953T	Pathogenic	0.554
NPC1	O15118-1.2	Q953V	Pathogenic	0.552
NPC1	O15118-1.2	Q953W	Pathogenic	0.527
NPC1	O15118-1.2	Q953Y	Pathogenic	0.505
NPC1	O15118-1.2	S954A	Pathogenic	0.563
NPC1	O15118-1.2	S954C	Pathogenic	0.699
NPC1	O15118-1.2	S954D	Pathogenic	0.642
NPC1	O15118-1.2	S954E	Pathogenic	0.676
NPC1	O15118-1.2	S954F	Pathogenic	0.779
NPC1	O15118-1.2	S954G	Pathogenic	0.702
NPC1	O15118-1.2	S954H	Pathogenic	0.789
NPC1	O15118-1.2	S954I	Pathogenic	0.766
NPC1	O15118-1.2	S954K	Pathogenic	0.685
NPC1	O15118-1.2	S954L	Pathogenic	0.772
NPC1	O15118-1.2	S954M	Pathogenic	0.729
NPC1	O15118-1.2	S954N	Pathogenic	0.57
NPC1	O15118-1.2	S954P	Pathogenic	0.722
NPC1	O15118-1.2	S954Q	Pathogenic	0.712
NPC1	O15118-1.2	S954R	Pathogenic	0.775
NPC1	O15118-1.2	S954T	Pathogenic	0.588
NPC1	O15118-1.2	S954V	Pathogenic	0.78
NPC1	O15118-1.2	S954W	Pathogenic	0.84
NPC1	O15118-1.2	S954Y	Pathogenic	0.828
NPC1	O15118-1.2	S955A	Neutral	0.311
NPC1	O15118-1.2	S955C	Neutral	0.449
NPC1	O15118-1.2	S955D	Neutral	0.386
NPC1	O15118-1.2	S955E	Neutral	0.423
NPC1	O15118-1.2	S955F	Pathogenic	0.552
NPC1	O15118-1.2	S955G	Neutral	0.452
NPC1	O15118-1.2	S955H	Pathogenic	0.568
NPC1	O15118-1.2	S955I	Pathogenic	0.535
NPC1	O15118-1.2	S955K	Neutral	0.432
NPC1	O15118-1.2	S955L	Pathogenic	0.543
NPC1	O15118-1.2	S955M	Neutral	0.486
NPC1	O15118-1.2	S955N	Neutral	0.318
NPC1	O15118-1.2	S955P	Neutral	0.477
NPC1	O15118-1.2	S955Q	Neutral	0.464
NPC1	O15118-1.2	S955R	Pathogenic	0.547
NPC1	O15118-1.2	S955T	Neutral	0.334
NPC1	O15118-1.2	S955V	Pathogenic	0.554
NPC1	O15118-1.2	S955W	Pathogenic	0.648
NPC1	O15118-1.2	S955Y	Pathogenic	0.628
NPC1	O15118-1.2	C956A	Pathogenic	0.955
NPC1	O15118-1.2	C956D	Pathogenic	0.977
NPC1	O15118-1.2	C956E	Pathogenic	0.987
NPC1	O15118-1.2	C956F	Pathogenic	0.981
NPC1	O15118-1.2	C956G	Pathogenic	0.985
NPC1	O15118-1.2	C956H	Pathogenic	0.986
NPC1	O15118-1.2	C956I	Pathogenic	0.971
NPC1	O15118-1.2	C956K	Pathogenic	0.981
NPC1	O15118-1.2	C956L	Pathogenic	0.972
NPC1	O15118-1.2	C956M	Pathogenic	0.976
NPC1	O15118-1.2	C956N	Pathogenic	0.979
NPC1	O15118-1.2	C956P	Pathogenic	0.986
NPC1	O15118-1.2	C956Q	Pathogenic	0.983
NPC1	O15118-1.2	C956R	Pathogenic	0.982
NPC1	O15118-1.2	C956S	Pathogenic	0.964
NPC1	O15118-1.2	C956T	Pathogenic	0.966
NPC1	O15118-1.2	C956V	Pathogenic	0.973
NPC1	O15118-1.2	C956W	Pathogenic	0.981
NPC1	O15118-1.2	C956Y	Pathogenic	0.986
NPC1	O15118-1.2	C957A	Pathogenic	0.955
NPC1	O15118-1.2	C957D	Pathogenic	0.978
NPC1	O15118-1.2	C957E	Pathogenic	0.987
NPC1	O15118-1.2	C957F	Pathogenic	0.982
NPC1	O15118-1.2	C957G	Pathogenic	0.986
NPC1	O15118-1.2	C957H	Pathogenic	0.986
NPC1	O15118-1.2	C957I	Pathogenic	0.971
NPC1	O15118-1.2	C957K	Pathogenic	0.981
NPC1	O15118-1.2	C957L	Pathogenic	0.972
NPC1	O15118-1.2	C957M	Pathogenic	0.976
NPC1	O15118-1.2	C957N	Pathogenic	0.979
NPC1	O15118-1.2	C957P	Pathogenic	0.986
NPC1	O15118-1.2	C957Q	Pathogenic	0.984
NPC1	O15118-1.2	C957R	Pathogenic	0.983
NPC1	O15118-1.2	C957S	Pathogenic	0.964
NPC1	O15118-1.2	C957T	Pathogenic	0.966
NPC1	O15118-1.2	C957V	Pathogenic	0.973
NPC1	O15118-1.2	C957W	Pathogenic	0.982
NPC1	O15118-1.2	C957Y	Pathogenic	0.986
NPC1	O15118-1.2	R958A	Pathogenic	0.882
NPC1	O15118-1.2	R958C	Pathogenic	0.92
NPC1	O15118-1.2	R958D	Pathogenic	0.932
NPC1	O15118-1.2	R958E	Pathogenic	0.844
NPC1	O15118-1.2	R958F	Pathogenic	0.868
NPC1	O15118-1.2	R958G	Pathogenic	0.932
NPC1	O15118-1.2	R958H	Pathogenic	0.799
NPC1	O15118-1.2	R958I	Pathogenic	0.875
NPC1	O15118-1.2	R958K	Pathogenic	0.706
NPC1	O15118-1.2	R958L	Pathogenic	0.831
NPC1	O15118-1.2	R958M	Pathogenic	0.796
NPC1	O15118-1.2	R958N	Pathogenic	0.853
NPC1	O15118-1.2	R958P	Pathogenic	0.893
NPC1	O15118-1.2	R958Q	Pathogenic	0.757
NPC1	O15118-1.2	R958S	Pathogenic	0.89
NPC1	O15118-1.2	R958T	Pathogenic	0.867
NPC1	O15118-1.2	R958V	Pathogenic	0.905
NPC1	O15118-1.2	R958W	Pathogenic	0.851
NPC1	O15118-1.2	R958Y	Pathogenic	0.85
NPC1	O15118-1.2	V959A	Neutral	0.289
NPC1	O15118-1.2	V959C	Neutral	0.4
NPC1	O15118-1.2	V959D	Neutral	0.439
NPC1	O15118-1.2	V959E	Neutral	0.344
NPC1	O15118-1.2	V959F	Neutral	0.39
NPC1	O15118-1.2	V959G	Pathogenic	0.567
NPC1	O15118-1.2	V959H	Pathogenic	0.512
NPC1	O15118-1.2	V959I	Neutral	0.113
NPC1	O15118-1.2	V959K	Neutral	0.353
NPC1	O15118-1.2	V959L	Neutral	0.221
NPC1	O15118-1.2	V959M	Neutral	0.249
NPC1	O15118-1.2	V959N	Neutral	0.445
NPC1	O15118-1.2	V959P	Neutral	0.468
NPC1	O15118-1.2	V959Q	Neutral	0.383
NPC1	O15118-1.2	V959R	Neutral	0.463
NPC1	O15118-1.2	V959S	Neutral	0.431
NPC1	O15118-1.2	V959T	Neutral	0.255
NPC1	O15118-1.2	V959W	Pathogenic	0.584
NPC1	O15118-1.2	V959Y	Neutral	0.424
NPC1	O15118-1.2	D960A	Neutral	0.383
NPC1	O15118-1.2	D960C	Neutral	0.394
NPC1	O15118-1.2	D960E	Neutral	0.149
NPC1	O15118-1.2	D960F	Neutral	0.386
NPC1	O15118-1.2	D960G	Neutral	0.344
NPC1	O15118-1.2	D960H	Neutral	0.313
NPC1	O15118-1.2	D960I	Neutral	0.369
NPC1	O15118-1.2	D960K	Neutral	0.387
NPC1	O15118-1.2	D960L	Neutral	0.471
NPC1	O15118-1.2	D960M	Neutral	0.415
NPC1	O15118-1.2	D960N	Neutral	0.19
NPC1	O15118-1.2	D960P	Neutral	0.242
NPC1	O15118-1.2	D960Q	Neutral	0.253
NPC1	O15118-1.2	D960R	Pathogenic	0.5
NPC1	O15118-1.2	D960S	Neutral	0.236
NPC1	O15118-1.2	D960T	Neutral	0.273
NPC1	O15118-1.2	D960V	Neutral	0.388
NPC1	O15118-1.2	D960W	Neutral	0.484
NPC1	O15118-1.2	D960Y	Neutral	0.462
NPC1	O15118-1.2	N961A	Neutral	0.235
NPC1	O15118-1.2	N961C	Neutral	0.243
NPC1	O15118-1.2	N961D	Neutral	0.096
NPC1	O15118-1.2	N961E	Neutral	0.147
NPC1	O15118-1.2	N961F	Neutral	0.227
NPC1	O15118-1.2	N961G	Neutral	0.15
NPC1	O15118-1.2	N961H	Neutral	0.089
NPC1	O15118-1.2	N961I	Neutral	0.215
NPC1	O15118-1.2	N961K	Neutral	0.152
NPC1	O15118-1.2	N961L	Neutral	0.22
NPC1	O15118-1.2	N961M	Neutral	0.183
NPC1	O15118-1.2	N961P	Neutral	0.189
NPC1	O15118-1.2	N961Q	Neutral	0.137
NPC1	O15118-1.2	N961R	Neutral	0.162
NPC1	O15118-1.2	N961S	Neutral	0.095
NPC1	O15118-1.2	N961T	Neutral	0.11
NPC1	O15118-1.2	N961V	Neutral	0.228
NPC1	O15118-1.2	N961W	Neutral	0.305
NPC1	O15118-1.2	N961Y	Neutral	0.214
NPC1	O15118-1.2	I962A	Neutral	0.104
NPC1	O15118-1.2	I962C	Neutral	0.114
NPC1	O15118-1.2	I962D	Neutral	0.132
NPC1	O15118-1.2	I962E	Neutral	0.124
NPC1	O15118-1.2	I962F	Neutral	0.089
NPC1	O15118-1.2	I962G	Neutral	0.272
NPC1	O15118-1.2	I962H	Neutral	0.148
NPC1	O15118-1.2	I962K	Neutral	0.11
NPC1	O15118-1.2	I962L	Neutral	0.039
NPC1	O15118-1.2	I962M	Neutral	0.049
NPC1	O15118-1.2	I962N	Neutral	0.135
NPC1	O15118-1.2	I962P	Neutral	0.2
NPC1	O15118-1.2	I962Q	Neutral	0.137
NPC1	O15118-1.2	I962R	Neutral	0.117
NPC1	O15118-1.2	I962S	Neutral	0.128
NPC1	O15118-1.2	I962T	Neutral	0.089
NPC1	O15118-1.2	I962V	Neutral	0.026
NPC1	O15118-1.2	I962W	Neutral	0.242
NPC1	O15118-1.2	I962Y	Neutral	0.102
NPC1	O15118-1.2	T963A	Pathogenic	0.59
NPC1	O15118-1.2	T963C	Pathogenic	0.602
NPC1	O15118-1.2	T963D	Pathogenic	0.57
NPC1	O15118-1.2	T963E	Pathogenic	0.601
NPC1	O15118-1.2	T963F	Pathogenic	0.677
NPC1	O15118-1.2	T963G	Pathogenic	0.766
NPC1	O15118-1.2	T963H	Pathogenic	0.751
NPC1	O15118-1.2	T963I	Pathogenic	0.571
NPC1	O15118-1.2	T963K	Pathogenic	0.611
NPC1	O15118-1.2	T963L	Pathogenic	0.579
NPC1	O15118-1.2	T963M	Pathogenic	0.616
NPC1	O15118-1.2	T963N	Neutral	0.489
NPC1	O15118-1.2	T963P	Pathogenic	0.617
NPC1	O15118-1.2	T963Q	Pathogenic	0.641
NPC1	O15118-1.2	T963R	Pathogenic	0.628
NPC1	O15118-1.2	T963S	Neutral	0.466
NPC1	O15118-1.2	T963V	Neutral	0.495
NPC1	O15118-1.2	T963W	Pathogenic	0.681
NPC1	O15118-1.2	T963Y	Pathogenic	0.741
NPC1	O15118-1.2	D964A	Pathogenic	0.508
NPC1	O15118-1.2	D964C	Pathogenic	0.52
NPC1	O15118-1.2	D964E	Neutral	0.226
NPC1	O15118-1.2	D964F	Pathogenic	0.512
NPC1	O15118-1.2	D964G	Neutral	0.466
NPC1	O15118-1.2	D964H	Neutral	0.431
NPC1	O15118-1.2	D964I	Neutral	0.494
NPC1	O15118-1.2	D964K	Pathogenic	0.513
NPC1	O15118-1.2	D964L	Pathogenic	0.598
NPC1	O15118-1.2	D964M	Pathogenic	0.541
NPC1	O15118-1.2	D964N	Neutral	0.281
NPC1	O15118-1.2	D964P	Neutral	0.348
NPC1	O15118-1.2	D964Q	Neutral	0.361
NPC1	O15118-1.2	D964R	Pathogenic	0.625
NPC1	O15118-1.2	D964S	Neutral	0.341
NPC1	O15118-1.2	D964T	Neutral	0.385
NPC1	O15118-1.2	D964V	Pathogenic	0.514
NPC1	O15118-1.2	D964W	Pathogenic	0.61
NPC1	O15118-1.2	D964Y	Pathogenic	0.589
NPC1	O15118-1.2	Q965A	Neutral	0.377
NPC1	O15118-1.2	Q965C	Neutral	0.483
NPC1	O15118-1.2	Q965D	Neutral	0.261
NPC1	O15118-1.2	Q965E	Neutral	0.133
NPC1	O15118-1.2	Q965F	Neutral	0.406
NPC1	O15118-1.2	Q965G	Pathogenic	0.525
NPC1	O15118-1.2	Q965H	Neutral	0.252
NPC1	O15118-1.2	Q965I	Neutral	0.389
NPC1	O15118-1.2	Q965K	Neutral	0.181
NPC1	O15118-1.2	Q965L	Neutral	0.31
NPC1	O15118-1.2	Q965M	Neutral	0.195
NPC1	O15118-1.2	Q965N	Neutral	0.266
NPC1	O15118-1.2	Q965P	Neutral	0.315
NPC1	O15118-1.2	Q965R	Neutral	0.192
NPC1	O15118-1.2	Q965S	Neutral	0.308
NPC1	O15118-1.2	Q965T	Neutral	0.345
NPC1	O15118-1.2	Q965V	Neutral	0.344
NPC1	O15118-1.2	Q965W	Neutral	0.321
NPC1	O15118-1.2	Q965Y	Neutral	0.302
NPC1	O15118-1.2	F966A	Pathogenic	0.966
NPC1	O15118-1.2	F966C	Pathogenic	0.969
NPC1	O15118-1.2	F966D	Pathogenic	0.962
NPC1	O15118-1.2	F966E	Pathogenic	0.959
NPC1	O15118-1.2	F966G	Pathogenic	0.977
NPC1	O15118-1.2	F966H	Pathogenic	0.93
NPC1	O15118-1.2	F966I	Pathogenic	0.938
NPC1	O15118-1.2	F966K	Pathogenic	0.947
NPC1	O15118-1.2	F966L	Pathogenic	0.936
NPC1	O15118-1.2	F966M	Pathogenic	0.926
NPC1	O15118-1.2	F966N	Pathogenic	0.963
NPC1	O15118-1.2	F966P	Pathogenic	0.984
NPC1	O15118-1.2	F966Q	Pathogenic	0.963
NPC1	O15118-1.2	F966R	Pathogenic	0.951
NPC1	O15118-1.2	F966S	Pathogenic	0.961
NPC1	O15118-1.2	F966T	Pathogenic	0.96
NPC1	O15118-1.2	F966V	Pathogenic	0.954
NPC1	O15118-1.2	F966W	Pathogenic	0.907
NPC1	O15118-1.2	F966Y	Pathogenic	0.778
NPC1	O15118-1.2	C967A	Pathogenic	0.946
NPC1	O15118-1.2	C967D	Pathogenic	0.973
NPC1	O15118-1.2	C967E	Pathogenic	0.984
NPC1	O15118-1.2	C967F	Pathogenic	0.977
NPC1	O15118-1.2	C967G	Pathogenic	0.983
NPC1	O15118-1.2	C967H	Pathogenic	0.983
NPC1	O15118-1.2	C967I	Pathogenic	0.965
NPC1	O15118-1.2	C967K	Pathogenic	0.977
NPC1	O15118-1.2	C967L	Pathogenic	0.966
NPC1	O15118-1.2	C967M	Pathogenic	0.971
NPC1	O15118-1.2	C967N	Pathogenic	0.975
NPC1	O15118-1.2	C967P	Pathogenic	0.983
NPC1	O15118-1.2	C967Q	Pathogenic	0.98
NPC1	O15118-1.2	C967R	Pathogenic	0.979
NPC1	O15118-1.2	C967S	Pathogenic	0.957
NPC1	O15118-1.2	C967T	Pathogenic	0.959
NPC1	O15118-1.2	C967V	Pathogenic	0.967
NPC1	O15118-1.2	C967W	Pathogenic	0.978
NPC1	O15118-1.2	C967Y	Pathogenic	0.983
NPC1	O15118-1.2	N968A	Pathogenic	0.523
NPC1	O15118-1.2	N968C	Pathogenic	0.534
NPC1	O15118-1.2	N968D	Neutral	0.276
NPC1	O15118-1.2	N968E	Neutral	0.38
NPC1	O15118-1.2	N968F	Pathogenic	0.511
NPC1	O15118-1.2	N968G	Neutral	0.386
NPC1	O15118-1.2	N968H	Neutral	0.259
NPC1	O15118-1.2	N968I	Neutral	0.493
NPC1	O15118-1.2	N968K	Neutral	0.39
NPC1	O15118-1.2	N968L	Pathogenic	0.502
NPC1	O15118-1.2	N968M	Neutral	0.444
NPC1	O15118-1.2	N968P	Neutral	0.454
NPC1	O15118-1.2	N968Q	Neutral	0.361
NPC1	O15118-1.2	N968R	Neutral	0.408
NPC1	O15118-1.2	N968S	Neutral	0.271
NPC1	O15118-1.2	N968T	Neutral	0.305
NPC1	O15118-1.2	N968V	Pathogenic	0.513
NPC1	O15118-1.2	N968W	Pathogenic	0.61
NPC1	O15118-1.2	N968Y	Neutral	0.493
NPC1	O15118-1.2	A969C	Pathogenic	0.657
NPC1	O15118-1.2	A969D	Pathogenic	0.789
NPC1	O15118-1.2	A969E	Pathogenic	0.748
NPC1	O15118-1.2	A969F	Pathogenic	0.81
NPC1	O15118-1.2	A969G	Pathogenic	0.684
NPC1	O15118-1.2	A969H	Pathogenic	0.856
NPC1	O15118-1.2	A969I	Pathogenic	0.73
NPC1	O15118-1.2	A969K	Pathogenic	0.755
NPC1	O15118-1.2	A969L	Pathogenic	0.737
NPC1	O15118-1.2	A969M	Pathogenic	0.766
NPC1	O15118-1.2	A969N	Pathogenic	0.803
NPC1	O15118-1.2	A969P	Pathogenic	0.759
NPC1	O15118-1.2	A969Q	Pathogenic	0.778
NPC1	O15118-1.2	A969R	Pathogenic	0.769
NPC1	O15118-1.2	A969S	Pathogenic	0.574
NPC1	O15118-1.2	A969T	Pathogenic	0.711
NPC1	O15118-1.2	A969V	Pathogenic	0.666
NPC1	O15118-1.2	A969W	Pathogenic	0.864
NPC1	O15118-1.2	A969Y	Pathogenic	0.854
NPC1	O15118-1.2	S970A	Neutral	0.339
NPC1	O15118-1.2	S970C	Neutral	0.48
NPC1	O15118-1.2	S970D	Neutral	0.416
NPC1	O15118-1.2	S970E	Neutral	0.453
NPC1	O15118-1.2	S970F	Pathogenic	0.583
NPC1	O15118-1.2	S970G	Neutral	0.483
NPC1	O15118-1.2	S970H	Pathogenic	0.598
NPC1	O15118-1.2	S970I	Pathogenic	0.565
NPC1	O15118-1.2	S970K	Neutral	0.463
NPC1	O15118-1.2	S970L	Pathogenic	0.574
NPC1	O15118-1.2	S970M	Pathogenic	0.517
NPC1	O15118-1.2	S970N	Neutral	0.345
NPC1	O15118-1.2	S970P	Pathogenic	0.508
NPC1	O15118-1.2	S970Q	Neutral	0.495
NPC1	O15118-1.2	S970R	Pathogenic	0.577
NPC1	O15118-1.2	S970T	Neutral	0.362
NPC1	O15118-1.2	S970V	Pathogenic	0.585
NPC1	O15118-1.2	S970W	Pathogenic	0.676
NPC1	O15118-1.2	S970Y	Pathogenic	0.656
NPC1	O15118-1.2	V971A	Neutral	0.449
NPC1	O15118-1.2	V971C	Pathogenic	0.572
NPC1	O15118-1.2	V971D	Pathogenic	0.61
NPC1	O15118-1.2	V971E	Pathogenic	0.512
NPC1	O15118-1.2	V971F	Pathogenic	0.561
NPC1	O15118-1.2	V971G	Pathogenic	0.724
NPC1	O15118-1.2	V971H	Pathogenic	0.677
NPC1	O15118-1.2	V971I	Neutral	0.203
NPC1	O15118-1.2	V971K	Pathogenic	0.522
NPC1	O15118-1.2	V971L	Neutral	0.362
NPC1	O15118-1.2	V971M	Neutral	0.399
NPC1	O15118-1.2	V971N	Pathogenic	0.616
NPC1	O15118-1.2	V971P	Pathogenic	0.637
NPC1	O15118-1.2	V971Q	Pathogenic	0.554
NPC1	O15118-1.2	V971R	Pathogenic	0.633
NPC1	O15118-1.2	V971S	Pathogenic	0.602
NPC1	O15118-1.2	V971T	Neutral	0.406
NPC1	O15118-1.2	V971W	Pathogenic	0.737
NPC1	O15118-1.2	V971Y	Pathogenic	0.595
NPC1	O15118-1.2	V972A	Neutral	0.234
NPC1	O15118-1.2	V972C	Neutral	0.333
NPC1	O15118-1.2	V972D	Neutral	0.37
NPC1	O15118-1.2	V972E	Neutral	0.282
NPC1	O15118-1.2	V972F	Neutral	0.323
NPC1	O15118-1.2	V972G	Neutral	0.495
NPC1	O15118-1.2	V972H	Neutral	0.44
NPC1	O15118-1.2	V972I	Neutral	0.087
NPC1	O15118-1.2	V972K	Neutral	0.29
NPC1	O15118-1.2	V972L	Neutral	0.175
NPC1	O15118-1.2	V972M	Neutral	0.199
NPC1	O15118-1.2	V972N	Neutral	0.376
NPC1	O15118-1.2	V972P	Neutral	0.397
NPC1	O15118-1.2	V972Q	Neutral	0.317
NPC1	O15118-1.2	V972R	Neutral	0.393
NPC1	O15118-1.2	V972S	Neutral	0.362
NPC1	O15118-1.2	V972T	Neutral	0.204
NPC1	O15118-1.2	V972W	Pathogenic	0.512
NPC1	O15118-1.2	V972Y	Neutral	0.355
NPC1	O15118-1.2	D973A	Pathogenic	0.521
NPC1	O15118-1.2	D973C	Pathogenic	0.532
NPC1	O15118-1.2	D973E	Neutral	0.235
NPC1	O15118-1.2	D973F	Pathogenic	0.524
NPC1	O15118-1.2	D973G	Neutral	0.479
NPC1	O15118-1.2	D973H	Neutral	0.444
NPC1	O15118-1.2	D973I	Pathogenic	0.507
NPC1	O15118-1.2	D973K	Pathogenic	0.526
NPC1	O15118-1.2	D973L	Pathogenic	0.61
NPC1	O15118-1.2	D973M	Pathogenic	0.554
NPC1	O15118-1.2	D973N	Neutral	0.292
NPC1	O15118-1.2	D973P	Neutral	0.359
NPC1	O15118-1.2	D973Q	Neutral	0.373
NPC1	O15118-1.2	D973R	Pathogenic	0.637
NPC1	O15118-1.2	D973S	Neutral	0.352
NPC1	O15118-1.2	D973T	Neutral	0.397
NPC1	O15118-1.2	D973V	Pathogenic	0.527
NPC1	O15118-1.2	D973W	Pathogenic	0.622
NPC1	O15118-1.2	D973Y	Pathogenic	0.601
NPC1	O15118-1.2	P974A	Neutral	0.402
NPC1	O15118-1.2	P974C	Pathogenic	0.576
NPC1	O15118-1.2	P974D	Neutral	0.291
NPC1	O15118-1.2	P974E	Neutral	0.324
NPC1	O15118-1.2	P974F	Pathogenic	0.662
NPC1	O15118-1.2	P974G	Pathogenic	0.5
NPC1	O15118-1.2	P974H	Neutral	0.49
NPC1	O15118-1.2	P974I	Pathogenic	0.554
NPC1	O15118-1.2	P974K	Neutral	0.333
NPC1	O15118-1.2	P974L	Pathogenic	0.562
NPC1	O15118-1.2	P974M	Pathogenic	0.505
NPC1	O15118-1.2	P974N	Neutral	0.397
NPC1	O15118-1.2	P974Q	Neutral	0.362
NPC1	O15118-1.2	P974R	Neutral	0.441
NPC1	O15118-1.2	P974S	Neutral	0.366
NPC1	O15118-1.2	P974T	Neutral	0.369
NPC1	O15118-1.2	P974V	Neutral	0.478
NPC1	O15118-1.2	P974W	Pathogenic	0.666
NPC1	O15118-1.2	P974Y	Pathogenic	0.646
NPC1	O15118-1.2	A975C	Neutral	0.138
NPC1	O15118-1.2	A975D	Neutral	0.237
NPC1	O15118-1.2	A975E	Neutral	0.198
NPC1	O15118-1.2	A975F	Neutral	0.262
NPC1	O15118-1.2	A975G	Neutral	0.153
NPC1	O15118-1.2	A975H	Neutral	0.331
NPC1	O15118-1.2	A975I	Neutral	0.183
NPC1	O15118-1.2	A975K	Neutral	0.204
NPC1	O15118-1.2	A975L	Neutral	0.189
NPC1	O15118-1.2	A975M	Neutral	0.214
NPC1	O15118-1.2	A975N	Neutral	0.253
NPC1	O15118-1.2	A975P	Neutral	0.208
NPC1	O15118-1.2	A975Q	Neutral	0.226
NPC1	O15118-1.2	A975R	Neutral	0.216
NPC1	O15118-1.2	A975S	Neutral	0.101
NPC1	O15118-1.2	A975T	Neutral	0.17
NPC1	O15118-1.2	A975V	Neutral	0.142
NPC1	O15118-1.2	A975W	Neutral	0.347
NPC1	O15118-1.2	A975Y	Neutral	0.326
NPC1	O15118-1.2	C976A	Pathogenic	0.955
NPC1	O15118-1.2	C976D	Pathogenic	0.978
NPC1	O15118-1.2	C976E	Pathogenic	0.987
NPC1	O15118-1.2	C976F	Pathogenic	0.982
NPC1	O15118-1.2	C976G	Pathogenic	0.986
NPC1	O15118-1.2	C976H	Pathogenic	0.986
NPC1	O15118-1.2	C976I	Pathogenic	0.971
NPC1	O15118-1.2	C976K	Pathogenic	0.981
NPC1	O15118-1.2	C976L	Pathogenic	0.972
NPC1	O15118-1.2	C976M	Pathogenic	0.976
NPC1	O15118-1.2	C976N	Pathogenic	0.979
NPC1	O15118-1.2	C976P	Pathogenic	0.986
NPC1	O15118-1.2	C976Q	Pathogenic	0.984
NPC1	O15118-1.2	C976R	Pathogenic	0.983
NPC1	O15118-1.2	C976S	Pathogenic	0.964
NPC1	O15118-1.2	C976T	Pathogenic	0.966
NPC1	O15118-1.2	C976V	Pathogenic	0.973
NPC1	O15118-1.2	C976W	Pathogenic	0.982
NPC1	O15118-1.2	C976Y	Pathogenic	0.986
NPC1	O15118-1.2	V977A	Neutral	0.126
NPC1	O15118-1.2	V977C	Neutral	0.191
NPC1	O15118-1.2	V977D	Neutral	0.217
NPC1	O15118-1.2	V977E	Neutral	0.156
NPC1	O15118-1.2	V977F	Neutral	0.184
NPC1	O15118-1.2	V977G	Neutral	0.317
NPC1	O15118-1.2	V977H	Neutral	0.271
NPC1	O15118-1.2	V977I	Neutral	0.043
NPC1	O15118-1.2	V977K	Neutral	0.162
NPC1	O15118-1.2	V977L	Neutral	0.091
NPC1	O15118-1.2	V977M	Neutral	0.105
NPC1	O15118-1.2	V977N	Neutral	0.221
NPC1	O15118-1.2	V977P	Neutral	0.237
NPC1	O15118-1.2	V977Q	Neutral	0.18
NPC1	O15118-1.2	V977R	Neutral	0.234
NPC1	O15118-1.2	V977S	Neutral	0.211
NPC1	O15118-1.2	V977T	Neutral	0.108
NPC1	O15118-1.2	V977W	Neutral	0.332
NPC1	O15118-1.2	V977Y	Neutral	0.206
NPC1	O15118-1.2	R978A	Neutral	0.409
NPC1	O15118-1.2	R978C	Pathogenic	0.516
NPC1	O15118-1.2	R978D	Pathogenic	0.558
NPC1	O15118-1.2	R978E	Neutral	0.333
NPC1	O15118-1.2	R978F	Neutral	0.378
NPC1	O15118-1.2	R978G	Pathogenic	0.559
NPC1	O15118-1.2	R978H	Neutral	0.268
NPC1	O15118-1.2	R978I	Neutral	0.392
NPC1	O15118-1.2	R978K	Neutral	0.182
NPC1	O15118-1.2	R978L	Neutral	0.312
NPC1	O15118-1.2	R978M	Neutral	0.265
NPC1	O15118-1.2	R978N	Neutral	0.348
NPC1	O15118-1.2	R978P	Neutral	0.436
NPC1	O15118-1.2	R978Q	Neutral	0.223
NPC1	O15118-1.2	R978S	Neutral	0.428
NPC1	O15118-1.2	R978T	Neutral	0.376
NPC1	O15118-1.2	R978V	Neutral	0.468
NPC1	O15118-1.2	R978W	Neutral	0.345
NPC1	O15118-1.2	R978Y	Neutral	0.344
NPC1	O15118-1.2	C979A	Pathogenic	0.955
NPC1	O15118-1.2	C979D	Pathogenic	0.978
NPC1	O15118-1.2	C979E	Pathogenic	0.987
NPC1	O15118-1.2	C979F	Pathogenic	0.982
NPC1	O15118-1.2	C979G	Pathogenic	0.986
NPC1	O15118-1.2	C979H	Pathogenic	0.986
NPC1	O15118-1.2	C979I	Pathogenic	0.971
NPC1	O15118-1.2	C979K	Pathogenic	0.981
NPC1	O15118-1.2	C979L	Pathogenic	0.972
NPC1	O15118-1.2	C979M	Pathogenic	0.976
NPC1	O15118-1.2	C979N	Pathogenic	0.979
NPC1	O15118-1.2	C979P	Pathogenic	0.986
NPC1	O15118-1.2	C979Q	Pathogenic	0.984
NPC1	O15118-1.2	C979R	Pathogenic	0.983
NPC1	O15118-1.2	C979S	Pathogenic	0.964
NPC1	O15118-1.2	C979T	Pathogenic	0.966
NPC1	O15118-1.2	C979V	Pathogenic	0.973
NPC1	O15118-1.2	C979W	Pathogenic	0.982
NPC1	O15118-1.2	C979Y	Pathogenic	0.986
NPC1	O15118-1.2	R980A	Pathogenic	0.57
NPC1	O15118-1.2	R980C	Pathogenic	0.672
NPC1	O15118-1.2	R980D	Pathogenic	0.707
NPC1	O15118-1.2	R980E	Neutral	0.489
NPC1	O15118-1.2	R980F	Pathogenic	0.538
NPC1	O15118-1.2	R980G	Pathogenic	0.708
NPC1	O15118-1.2	R980H	Neutral	0.413
NPC1	O15118-1.2	R980I	Pathogenic	0.553
NPC1	O15118-1.2	R980K	Neutral	0.298
NPC1	O15118-1.2	R980L	Neutral	0.465
NPC1	O15118-1.2	R980M	Neutral	0.409
NPC1	O15118-1.2	R980N	Pathogenic	0.506
NPC1	O15118-1.2	R980P	Pathogenic	0.597
NPC1	O15118-1.2	R980Q	Neutral	0.355
NPC1	O15118-1.2	R980S	Pathogenic	0.589
NPC1	O15118-1.2	R980T	Pathogenic	0.536
NPC1	O15118-1.2	R980V	Pathogenic	0.628
NPC1	O15118-1.2	R980W	Pathogenic	0.502
NPC1	O15118-1.2	R980Y	Pathogenic	0.501
NPC1	O15118-1.2	P981A	Pathogenic	0.537
NPC1	O15118-1.2	P981C	Pathogenic	0.701
NPC1	O15118-1.2	P981D	Neutral	0.415
NPC1	O15118-1.2	P981E	Neutral	0.452
NPC1	O15118-1.2	P981F	Pathogenic	0.772
NPC1	O15118-1.2	P981G	Pathogenic	0.633
NPC1	O15118-1.2	P981H	Pathogenic	0.624
NPC1	O15118-1.2	P981I	Pathogenic	0.682
NPC1	O15118-1.2	P981K	Neutral	0.462
NPC1	O15118-1.2	P981L	Pathogenic	0.689
NPC1	O15118-1.2	P981M	Pathogenic	0.638
NPC1	O15118-1.2	P981N	Pathogenic	0.532
NPC1	O15118-1.2	P981Q	Neutral	0.495
NPC1	O15118-1.2	P981R	Pathogenic	0.577
NPC1	O15118-1.2	P981S	Neutral	0.499
NPC1	O15118-1.2	P981T	Pathogenic	0.502
NPC1	O15118-1.2	P981V	Pathogenic	0.612
NPC1	O15118-1.2	P981W	Pathogenic	0.775
NPC1	O15118-1.2	P981Y	Pathogenic	0.759
NPC1	O15118-1.2	L982A	Neutral	0.234
NPC1	O15118-1.2	L982C	Neutral	0.255
NPC1	O15118-1.2	L982D	Neutral	0.371
NPC1	O15118-1.2	L982E	Neutral	0.273
NPC1	O15118-1.2	L982F	Neutral	0.196
NPC1	O15118-1.2	L982G	Neutral	0.497
NPC1	O15118-1.2	L982H	Neutral	0.315
NPC1	O15118-1.2	L982I	Neutral	0.095
NPC1	O15118-1.2	L982K	Neutral	0.181
NPC1	O15118-1.2	L982M	Neutral	0.085
NPC1	O15118-1.2	L982N	Neutral	0.291
NPC1	O15118-1.2	L982P	Neutral	0.398
NPC1	O15118-1.2	L982Q	Neutral	0.221
NPC1	O15118-1.2	L982R	Neutral	0.193
NPC1	O15118-1.2	L982S	Neutral	0.279
NPC1	O15118-1.2	L982T	Neutral	0.205
NPC1	O15118-1.2	L982V	Neutral	0.132
NPC1	O15118-1.2	L982W	Neutral	0.348
NPC1	O15118-1.2	L982Y	Neutral	0.23
NPC1	O15118-1.2	T983A	Neutral	0.348
NPC1	O15118-1.2	T983C	Neutral	0.358
NPC1	O15118-1.2	T983D	Neutral	0.329
NPC1	O15118-1.2	T983E	Neutral	0.358
NPC1	O15118-1.2	T983F	Neutral	0.437
NPC1	O15118-1.2	T983G	Pathogenic	0.547
NPC1	O15118-1.2	T983H	Pathogenic	0.528
NPC1	O15118-1.2	T983I	Neutral	0.329
NPC1	O15118-1.2	T983K	Neutral	0.367
NPC1	O15118-1.2	T983L	Neutral	0.337
NPC1	O15118-1.2	T983M	Neutral	0.373
NPC1	O15118-1.2	T983N	Neutral	0.262
NPC1	O15118-1.2	T983P	Neutral	0.373
NPC1	O15118-1.2	T983Q	Neutral	0.398
NPC1	O15118-1.2	T983R	Neutral	0.385
NPC1	O15118-1.2	T983S	Neutral	0.244
NPC1	O15118-1.2	T983V	Neutral	0.266
NPC1	O15118-1.2	T983W	Neutral	0.441
NPC1	O15118-1.2	T983Y	Pathogenic	0.515
NPC1	O15118-1.2	P984A	Neutral	0.296
NPC1	O15118-1.2	P984C	Neutral	0.46
NPC1	O15118-1.2	P984D	Neutral	0.205
NPC1	O15118-1.2	P984E	Neutral	0.231
NPC1	O15118-1.2	P984F	Pathogenic	0.551
NPC1	O15118-1.2	P984G	Neutral	0.385
NPC1	O15118-1.2	P984H	Neutral	0.375
NPC1	O15118-1.2	P984I	Neutral	0.437
NPC1	O15118-1.2	P984K	Neutral	0.238
NPC1	O15118-1.2	P984L	Neutral	0.446
NPC1	O15118-1.2	P984M	Neutral	0.39
NPC1	O15118-1.2	P984N	Neutral	0.292
NPC1	O15118-1.2	P984Q	Neutral	0.262
NPC1	O15118-1.2	P984R	Neutral	0.331
NPC1	O15118-1.2	P984S	Neutral	0.265
NPC1	O15118-1.2	P984T	Neutral	0.268
NPC1	O15118-1.2	P984V	Neutral	0.364
NPC1	O15118-1.2	P984W	Pathogenic	0.555
NPC1	O15118-1.2	P984Y	Pathogenic	0.533
NPC1	O15118-1.2	E985A	Neutral	0.475
NPC1	O15118-1.2	E985C	Pathogenic	0.672
NPC1	O15118-1.2	E985D	Neutral	0.244
NPC1	O15118-1.2	E985F	Pathogenic	0.52
NPC1	O15118-1.2	E985G	Pathogenic	0.623
NPC1	O15118-1.2	E985H	Neutral	0.348
NPC1	O15118-1.2	E985I	Pathogenic	0.502
NPC1	O15118-1.2	E985K	Neutral	0.316
NPC1	O15118-1.2	E985L	Pathogenic	0.511
NPC1	O15118-1.2	E985M	Neutral	0.454
NPC1	O15118-1.2	E985N	Neutral	0.411
NPC1	O15118-1.2	E985P	Neutral	0.407
NPC1	O15118-1.2	E985Q	Neutral	0.213
NPC1	O15118-1.2	E985R	Neutral	0.422
NPC1	O15118-1.2	E985S	Neutral	0.399
NPC1	O15118-1.2	E985T	Neutral	0.44
NPC1	O15118-1.2	E985V	Neutral	0.438
NPC1	O15118-1.2	E985W	Pathogenic	0.524
NPC1	O15118-1.2	E985Y	Pathogenic	0.502
NPC1	O15118-1.2	G986A	Neutral	0.485
NPC1	O15118-1.2	G986C	Pathogenic	0.728
NPC1	O15118-1.2	G986D	Pathogenic	0.578
NPC1	O15118-1.2	G986E	Pathogenic	0.702
NPC1	O15118-1.2	G986F	Pathogenic	0.734
NPC1	O15118-1.2	G986H	Pathogenic	0.746
NPC1	O15118-1.2	G986I	Pathogenic	0.791
NPC1	O15118-1.2	G986K	Pathogenic	0.71
NPC1	O15118-1.2	G986L	Pathogenic	0.796
NPC1	O15118-1.2	G986M	Pathogenic	0.757
NPC1	O15118-1.2	G986N	Pathogenic	0.504
NPC1	O15118-1.2	G986P	Pathogenic	0.671
NPC1	O15118-1.2	G986Q	Pathogenic	0.736
NPC1	O15118-1.2	G986R	Pathogenic	0.725
NPC1	O15118-1.2	G986S	Pathogenic	0.516
NPC1	O15118-1.2	G986T	Pathogenic	0.708
NPC1	O15118-1.2	G986V	Pathogenic	0.736
NPC1	O15118-1.2	G986W	Pathogenic	0.656
NPC1	O15118-1.2	G986Y	Pathogenic	0.79
NPC1	O15118-1.2	K987A	Pathogenic	0.544
NPC1	O15118-1.2	K987C	Pathogenic	0.648
NPC1	O15118-1.2	K987D	Pathogenic	0.597
NPC1	O15118-1.2	K987E	Neutral	0.37
NPC1	O15118-1.2	K987F	Pathogenic	0.512
NPC1	O15118-1.2	K987G	Pathogenic	0.686
NPC1	O15118-1.2	K987H	Neutral	0.482
NPC1	O15118-1.2	K987I	Pathogenic	0.527
NPC1	O15118-1.2	K987L	Neutral	0.439
NPC1	O15118-1.2	K987M	Neutral	0.384
NPC1	O15118-1.2	K987N	Neutral	0.48
NPC1	O15118-1.2	K987P	Neutral	0.476
NPC1	O15118-1.2	K987Q	Neutral	0.331
NPC1	O15118-1.2	K987R	Neutral	0.292
NPC1	O15118-1.2	K987S	Neutral	0.468
NPC1	O15118-1.2	K987T	Pathogenic	0.509
NPC1	O15118-1.2	K987V	Pathogenic	0.508
NPC1	O15118-1.2	K987W	Pathogenic	0.516
NPC1	O15118-1.2	K987Y	Neutral	0.493
NPC1	O15118-1.2	Q988A	Neutral	0.445
NPC1	O15118-1.2	Q988C	Pathogenic	0.553
NPC1	O15118-1.2	Q988D	Neutral	0.319
NPC1	O15118-1.2	Q988E	Neutral	0.168
NPC1	O15118-1.2	Q988F	Neutral	0.475
NPC1	O15118-1.2	Q988G	Pathogenic	0.594
NPC1	O15118-1.2	Q988H	Neutral	0.308
NPC1	O15118-1.2	Q988I	Neutral	0.457
NPC1	O15118-1.2	Q988K	Neutral	0.226
NPC1	O15118-1.2	Q988L	Neutral	0.372
NPC1	O15118-1.2	Q988M	Neutral	0.243
NPC1	O15118-1.2	Q988N	Neutral	0.324
NPC1	O15118-1.2	Q988P	Neutral	0.378
NPC1	O15118-1.2	Q988R	Neutral	0.239
NPC1	O15118-1.2	Q988S	Neutral	0.371
NPC1	O15118-1.2	Q988T	Neutral	0.411
NPC1	O15118-1.2	Q988V	Neutral	0.409
NPC1	O15118-1.2	Q988W	Neutral	0.385
NPC1	O15118-1.2	Q988Y	Neutral	0.364
NPC1	O15118-1.2	R989A	Pathogenic	0.966
NPC1	O15118-1.2	R989C	Pathogenic	0.978
NPC1	O15118-1.2	R989D	Pathogenic	0.981
NPC1	O15118-1.2	R989E	Pathogenic	0.953
NPC1	O15118-1.2	R989F	Pathogenic	0.961
NPC1	O15118-1.2	R989G	Pathogenic	0.981
NPC1	O15118-1.2	R989H	Pathogenic	0.937
NPC1	O15118-1.2	R989I	Pathogenic	0.963
NPC1	O15118-1.2	R989K	Pathogenic	0.901
NPC1	O15118-1.2	R989L	Pathogenic	0.949
NPC1	O15118-1.2	R989M	Pathogenic	0.936
NPC1	O15118-1.2	R989N	Pathogenic	0.956
NPC1	O15118-1.2	R989P	Pathogenic	0.969
NPC1	O15118-1.2	R989Q	Pathogenic	0.921
NPC1	O15118-1.2	R989S	Pathogenic	0.968
NPC1	O15118-1.2	R989T	Pathogenic	0.961
NPC1	O15118-1.2	R989V	Pathogenic	0.973
NPC1	O15118-1.2	R989W	Pathogenic	0.956
NPC1	O15118-1.2	R989Y	Pathogenic	0.955
NPC1	O15118-1.2	P990A	Pathogenic	0.962
NPC1	O15118-1.2	P990C	Pathogenic	0.981
NPC1	O15118-1.2	P990D	Pathogenic	0.939
NPC1	O15118-1.2	P990E	Pathogenic	0.947
NPC1	O15118-1.2	P990F	Pathogenic	0.987
NPC1	O15118-1.2	P990G	Pathogenic	0.974
NPC1	O15118-1.2	P990H	Pathogenic	0.973
NPC1	O15118-1.2	P990I	Pathogenic	0.979
NPC1	O15118-1.2	P990K	Pathogenic	0.949
NPC1	O15118-1.2	P990L	Pathogenic	0.98
NPC1	O15118-1.2	P990M	Pathogenic	0.975
NPC1	O15118-1.2	P990N	Pathogenic	0.961
NPC1	O15118-1.2	P990Q	Pathogenic	0.955
NPC1	O15118-1.2	P990R	Pathogenic	0.967
NPC1	O15118-1.2	P990S	Pathogenic	0.956
NPC1	O15118-1.2	P990T	Pathogenic	0.957
NPC1	O15118-1.2	P990V	Pathogenic	0.972
NPC1	O15118-1.2	P990W	Pathogenic	0.987
NPC1	O15118-1.2	P990Y	Pathogenic	0.986
NPC1	O15118-1.2	Q991A	Neutral	0.408
NPC1	O15118-1.2	Q991C	Pathogenic	0.515
NPC1	O15118-1.2	Q991D	Neutral	0.287
NPC1	O15118-1.2	Q991E	Neutral	0.149
NPC1	O15118-1.2	Q991F	Neutral	0.438
NPC1	O15118-1.2	Q991G	Pathogenic	0.558
NPC1	O15118-1.2	Q991H	Neutral	0.277
NPC1	O15118-1.2	Q991I	Neutral	0.421
NPC1	O15118-1.2	Q991K	Neutral	0.201
NPC1	O15118-1.2	Q991L	Neutral	0.338
NPC1	O15118-1.2	Q991M	Neutral	0.216
NPC1	O15118-1.2	Q991N	Neutral	0.292
NPC1	O15118-1.2	Q991P	Neutral	0.344
NPC1	O15118-1.2	Q991R	Neutral	0.213
NPC1	O15118-1.2	Q991S	Neutral	0.337
NPC1	O15118-1.2	Q991T	Neutral	0.375
NPC1	O15118-1.2	Q991V	Neutral	0.373
NPC1	O15118-1.2	Q991W	Neutral	0.35
NPC1	O15118-1.2	Q991Y	Neutral	0.33
NPC1	O15118-1.2	G992A	Neutral	0.407
NPC1	O15118-1.2	G992C	Pathogenic	0.662
NPC1	O15118-1.2	G992D	Pathogenic	0.5
NPC1	O15118-1.2	G992E	Pathogenic	0.632
NPC1	O15118-1.2	G992F	Pathogenic	0.668
NPC1	O15118-1.2	G992H	Pathogenic	0.682
NPC1	O15118-1.2	G992I	Pathogenic	0.734
NPC1	O15118-1.2	G992K	Pathogenic	0.641
NPC1	O15118-1.2	G992L	Pathogenic	0.74
NPC1	O15118-1.2	G992M	Pathogenic	0.694
NPC1	O15118-1.2	G992N	Neutral	0.426
NPC1	O15118-1.2	G992P	Pathogenic	0.598
NPC1	O15118-1.2	G992Q	Pathogenic	0.67
NPC1	O15118-1.2	G992R	Pathogenic	0.658
NPC1	O15118-1.2	G992S	Neutral	0.438
NPC1	O15118-1.2	G992T	Pathogenic	0.639
NPC1	O15118-1.2	G992V	Pathogenic	0.67
NPC1	O15118-1.2	G992W	Pathogenic	0.582
NPC1	O15118-1.2	G992Y	Pathogenic	0.733
NPC1	O15118-1.2	G993A	Neutral	0.094
NPC1	O15118-1.2	G993C	Neutral	0.229
NPC1	O15118-1.2	G993D	Neutral	0.132
NPC1	O15118-1.2	G993E	Neutral	0.207
NPC1	O15118-1.2	G993F	Neutral	0.234
NPC1	O15118-1.2	G993H	Neutral	0.245
NPC1	O15118-1.2	G993I	Neutral	0.295
NPC1	O15118-1.2	G993K	Neutral	0.213
NPC1	O15118-1.2	G993L	Neutral	0.302
NPC1	O15118-1.2	G993M	Neutral	0.256
NPC1	O15118-1.2	G993N	Neutral	0.101
NPC1	O15118-1.2	G993P	Neutral	0.184
NPC1	O15118-1.2	G993Q	Neutral	0.236
NPC1	O15118-1.2	G993R	Neutral	0.226
NPC1	O15118-1.2	G993S	Neutral	0.106
NPC1	O15118-1.2	G993T	Neutral	0.212
NPC1	O15118-1.2	G993V	Neutral	0.236
NPC1	O15118-1.2	G993W	Neutral	0.174
NPC1	O15118-1.2	G993Y	Neutral	0.295
NPC1	O15118-1.2	D994A	Pathogenic	0.757
NPC1	O15118-1.2	D994C	Pathogenic	0.765
NPC1	O15118-1.2	D994E	Neutral	0.467
NPC1	O15118-1.2	D994F	Pathogenic	0.759
NPC1	O15118-1.2	D994G	Pathogenic	0.724
NPC1	O15118-1.2	D994H	Pathogenic	0.695
NPC1	O15118-1.2	D994I	Pathogenic	0.746
NPC1	O15118-1.2	D994K	Pathogenic	0.76
NPC1	O15118-1.2	D994L	Pathogenic	0.817
NPC1	O15118-1.2	D994M	Pathogenic	0.78
NPC1	O15118-1.2	D994N	Pathogenic	0.541
NPC1	O15118-1.2	D994P	Pathogenic	0.616
NPC1	O15118-1.2	D994Q	Pathogenic	0.63
NPC1	O15118-1.2	D994R	Pathogenic	0.834
NPC1	O15118-1.2	D994S	Pathogenic	0.608
NPC1	O15118-1.2	D994T	Pathogenic	0.653
NPC1	O15118-1.2	D994V	Pathogenic	0.761
NPC1	O15118-1.2	D994W	Pathogenic	0.825
NPC1	O15118-1.2	D994Y	Pathogenic	0.812
NPC1	O15118-1.2	F995A	Pathogenic	0.967
NPC1	O15118-1.2	F995C	Pathogenic	0.97
NPC1	O15118-1.2	F995D	Pathogenic	0.963
NPC1	O15118-1.2	F995E	Pathogenic	0.961
NPC1	O15118-1.2	F995G	Pathogenic	0.978
NPC1	O15118-1.2	F995H	Pathogenic	0.932
NPC1	O15118-1.2	F995I	Pathogenic	0.94
NPC1	O15118-1.2	F995K	Pathogenic	0.949
NPC1	O15118-1.2	F995L	Pathogenic	0.938
NPC1	O15118-1.2	F995M	Pathogenic	0.929
NPC1	O15118-1.2	F995N	Pathogenic	0.964
NPC1	O15118-1.2	F995P	Pathogenic	0.984
NPC1	O15118-1.2	F995Q	Pathogenic	0.965
NPC1	O15118-1.2	F995R	Pathogenic	0.952
NPC1	O15118-1.2	F995S	Pathogenic	0.962
NPC1	O15118-1.2	F995T	Pathogenic	0.961
NPC1	O15118-1.2	F995V	Pathogenic	0.955
NPC1	O15118-1.2	F995W	Pathogenic	0.91
NPC1	O15118-1.2	F995Y	Pathogenic	0.784
NPC1	O15118-1.2	M996A	Neutral	0.488
NPC1	O15118-1.2	M996C	Pathogenic	0.515
NPC1	O15118-1.2	M996D	Pathogenic	0.555
NPC1	O15118-1.2	M996E	Neutral	0.442
NPC1	O15118-1.2	M996F	Neutral	0.356
NPC1	O15118-1.2	M996G	Pathogenic	0.676
NPC1	O15118-1.2	M996H	Neutral	0.492
NPC1	O15118-1.2	M996I	Neutral	0.26
NPC1	O15118-1.2	M996K	Neutral	0.319
NPC1	O15118-1.2	M996L	Neutral	0.198
NPC1	O15118-1.2	M996N	Neutral	0.465
NPC1	O15118-1.2	M996P	Pathogenic	0.583
NPC1	O15118-1.2	M996Q	Neutral	0.29
NPC1	O15118-1.2	M996R	Neutral	0.335
NPC1	O15118-1.2	M996S	Neutral	0.45
NPC1	O15118-1.2	M996T	Neutral	0.444
NPC1	O15118-1.2	M996V	Neutral	0.321
NPC1	O15118-1.2	M996W	Neutral	0.453
NPC1	O15118-1.2	M996Y	Neutral	0.482
NPC1	O15118-1.2	R997A	Pathogenic	0.545
NPC1	O15118-1.2	R997C	Pathogenic	0.649
NPC1	O15118-1.2	R997D	Pathogenic	0.686
NPC1	O15118-1.2	R997E	Neutral	0.464
NPC1	O15118-1.2	R997F	Pathogenic	0.512
NPC1	O15118-1.2	R997G	Pathogenic	0.687
NPC1	O15118-1.2	R997H	Neutral	0.388
NPC1	O15118-1.2	R997I	Pathogenic	0.528
NPC1	O15118-1.2	R997K	Neutral	0.278
NPC1	O15118-1.2	R997L	Neutral	0.44
NPC1	O15118-1.2	R997M	Neutral	0.385
NPC1	O15118-1.2	R997N	Neutral	0.481
NPC1	O15118-1.2	R997P	Pathogenic	0.572
NPC1	O15118-1.2	R997Q	Neutral	0.332
NPC1	O15118-1.2	R997S	Pathogenic	0.565
NPC1	O15118-1.2	R997T	Pathogenic	0.51
NPC1	O15118-1.2	R997V	Pathogenic	0.604
NPC1	O15118-1.2	R997W	Neutral	0.477
NPC1	O15118-1.2	R997Y	Neutral	0.476
NPC1	O15118-1.2	F998A	Pathogenic	0.86
NPC1	O15118-1.2	F998C	Pathogenic	0.873
NPC1	O15118-1.2	F998D	Pathogenic	0.845
NPC1	O15118-1.2	F998E	Pathogenic	0.837
NPC1	O15118-1.2	F998G	Pathogenic	0.901
NPC1	O15118-1.2	F998H	Pathogenic	0.743
NPC1	O15118-1.2	F998I	Pathogenic	0.766
NPC1	O15118-1.2	F998K	Pathogenic	0.796
NPC1	O15118-1.2	F998L	Pathogenic	0.762
NPC1	O15118-1.2	F998M	Pathogenic	0.732
NPC1	O15118-1.2	F998N	Pathogenic	0.849
NPC1	O15118-1.2	F998P	Pathogenic	0.93
NPC1	O15118-1.2	F998Q	Pathogenic	0.851
NPC1	O15118-1.2	F998R	Pathogenic	0.807
NPC1	O15118-1.2	F998S	Pathogenic	0.841
NPC1	O15118-1.2	F998T	Pathogenic	0.838
NPC1	O15118-1.2	F998V	Pathogenic	0.818
NPC1	O15118-1.2	F998W	Pathogenic	0.68
NPC1	O15118-1.2	F998Y	Neutral	0.432
NPC1	O15118-1.2	L999A	Pathogenic	0.863
NPC1	O15118-1.2	L999C	Pathogenic	0.876
NPC1	O15118-1.2	L999D	Pathogenic	0.924
NPC1	O15118-1.2	L999E	Pathogenic	0.886
NPC1	O15118-1.2	L999F	Pathogenic	0.834
NPC1	O15118-1.2	L999G	Pathogenic	0.953
NPC1	O15118-1.2	L999H	Pathogenic	0.905
NPC1	O15118-1.2	L999I	Pathogenic	0.684
NPC1	O15118-1.2	L999K	Pathogenic	0.821
NPC1	O15118-1.2	L999M	Pathogenic	0.657
NPC1	O15118-1.2	L999N	Pathogenic	0.895
NPC1	O15118-1.2	L999P	Pathogenic	0.932
NPC1	O15118-1.2	L999Q	Pathogenic	0.854
NPC1	O15118-1.2	L999R	Pathogenic	0.831
NPC1	O15118-1.2	L999S	Pathogenic	0.889
NPC1	O15118-1.2	L999T	Pathogenic	0.842
NPC1	O15118-1.2	L999V	Pathogenic	0.759
NPC1	O15118-1.2	L999W	Pathogenic	0.917
NPC1	O15118-1.2	L999Y	Pathogenic	0.86
NPC1	O15118-1.2	P1000A	Pathogenic	0.838
NPC1	O15118-1.2	P1000C	Pathogenic	0.913
NPC1	O15118-1.2	P1000D	Pathogenic	0.76
NPC1	O15118-1.2	P1000E	Pathogenic	0.786
NPC1	O15118-1.2	P1000F	Pathogenic	0.938
NPC1	O15118-1.2	P1000G	Pathogenic	0.885
NPC1	O15118-1.2	P1000H	Pathogenic	0.881
NPC1	O15118-1.2	P1000I	Pathogenic	0.905
NPC1	O15118-1.2	P1000K	Pathogenic	0.793
NPC1	O15118-1.2	P1000L	Pathogenic	0.908
NPC1	O15118-1.2	P1000M	Pathogenic	0.887
NPC1	O15118-1.2	P1000N	Pathogenic	0.835
NPC1	O15118-1.2	P1000Q	Pathogenic	0.813
NPC1	O15118-1.2	P1000R	Pathogenic	0.859
NPC1	O15118-1.2	P1000S	Pathogenic	0.816
NPC1	O15118-1.2	P1000T	Pathogenic	0.818
NPC1	O15118-1.2	P1000V	Pathogenic	0.875
NPC1	O15118-1.2	P1000W	Pathogenic	0.939
NPC1	O15118-1.2	P1000Y	Pathogenic	0.933
NPC1	O15118-1.2	M1001A	Pathogenic	0.666
NPC1	O15118-1.2	M1001C	Pathogenic	0.69
NPC1	O15118-1.2	M1001D	Pathogenic	0.723
NPC1	O15118-1.2	M1001E	Pathogenic	0.625
NPC1	O15118-1.2	M1001F	Pathogenic	0.537
NPC1	O15118-1.2	M1001G	Pathogenic	0.814
NPC1	O15118-1.2	M1001H	Pathogenic	0.671
NPC1	O15118-1.2	M1001I	Neutral	0.424
NPC1	O15118-1.2	M1001K	Neutral	0.496
NPC1	O15118-1.2	M1001L	Neutral	0.341
NPC1	O15118-1.2	M1001N	Pathogenic	0.646
NPC1	O15118-1.2	M1001P	Pathogenic	0.746
NPC1	O15118-1.2	M1001Q	Neutral	0.462
NPC1	O15118-1.2	M1001R	Pathogenic	0.514
NPC1	O15118-1.2	M1001S	Pathogenic	0.632
NPC1	O15118-1.2	M1001T	Pathogenic	0.627
NPC1	O15118-1.2	M1001V	Neutral	0.498
NPC1	O15118-1.2	M1001W	Pathogenic	0.634
NPC1	O15118-1.2	M1001Y	Pathogenic	0.661
NPC1	O15118-1.2	F1002A	Pathogenic	0.953
NPC1	O15118-1.2	F1002C	Pathogenic	0.958
NPC1	O15118-1.2	F1002D	Pathogenic	0.948
NPC1	O15118-1.2	F1002E	Pathogenic	0.944
NPC1	O15118-1.2	F1002G	Pathogenic	0.968
NPC1	O15118-1.2	F1002H	Pathogenic	0.906
NPC1	O15118-1.2	F1002I	Pathogenic	0.916
NPC1	O15118-1.2	F1002K	Pathogenic	0.928
NPC1	O15118-1.2	F1002L	Pathogenic	0.914
NPC1	O15118-1.2	F1002M	Pathogenic	0.901
NPC1	O15118-1.2	F1002N	Pathogenic	0.949
NPC1	O15118-1.2	F1002P	Pathogenic	0.978
NPC1	O15118-1.2	F1002Q	Pathogenic	0.95
NPC1	O15118-1.2	F1002R	Pathogenic	0.933
NPC1	O15118-1.2	F1002S	Pathogenic	0.946
NPC1	O15118-1.2	F1002T	Pathogenic	0.945
NPC1	O15118-1.2	F1002V	Pathogenic	0.937
NPC1	O15118-1.2	F1002W	Pathogenic	0.876
NPC1	O15118-1.2	F1002Y	Pathogenic	0.717
NPC1	O15118-1.2	L1003A	Pathogenic	0.948
NPC1	O15118-1.2	L1003C	Pathogenic	0.953
NPC1	O15118-1.2	L1003D	Pathogenic	0.972
NPC1	O15118-1.2	L1003E	Pathogenic	0.957
NPC1	O15118-1.2	L1003F	Pathogenic	0.935
NPC1	O15118-1.2	L1003G	Pathogenic	0.983
NPC1	O15118-1.2	L1003H	Pathogenic	0.964
NPC1	O15118-1.2	L1003I	Pathogenic	0.861
NPC1	O15118-1.2	L1003K	Pathogenic	0.929
NPC1	O15118-1.2	L1003M	Pathogenic	0.846
NPC1	O15118-1.2	L1003N	Pathogenic	0.96
NPC1	O15118-1.2	L1003P	Pathogenic	0.975
NPC1	O15118-1.2	L1003Q	Pathogenic	0.944
NPC1	O15118-1.2	L1003R	Pathogenic	0.934
NPC1	O15118-1.2	L1003S	Pathogenic	0.958
NPC1	O15118-1.2	L1003T	Pathogenic	0.938
NPC1	O15118-1.2	L1003V	Pathogenic	0.9
NPC1	O15118-1.2	L1003W	Pathogenic	0.969
NPC1	O15118-1.2	L1003Y	Pathogenic	0.946
NPC1	O15118-1.2	S1004A	Neutral	0.194
NPC1	O15118-1.2	S1004C	Neutral	0.303
NPC1	O15118-1.2	S1004D	Neutral	0.251
NPC1	O15118-1.2	S1004E	Neutral	0.28
NPC1	O15118-1.2	S1004F	Neutral	0.396
NPC1	O15118-1.2	S1004G	Neutral	0.306
NPC1	O15118-1.2	S1004H	Neutral	0.411
NPC1	O15118-1.2	S1004I	Neutral	0.38
NPC1	O15118-1.2	S1004K	Neutral	0.289
NPC1	O15118-1.2	S1004L	Neutral	0.388
NPC1	O15118-1.2	S1004M	Neutral	0.335
NPC1	O15118-1.2	S1004N	Neutral	0.199
NPC1	O15118-1.2	S1004P	Neutral	0.327
NPC1	O15118-1.2	S1004Q	Neutral	0.316
NPC1	O15118-1.2	S1004R	Neutral	0.391
NPC1	O15118-1.2	S1004T	Neutral	0.21
NPC1	O15118-1.2	S1004V	Neutral	0.399
NPC1	O15118-1.2	S1004W	Neutral	0.495
NPC1	O15118-1.2	S1004Y	Neutral	0.473
NPC1	O15118-1.2	D1005A	Pathogenic	0.952
NPC1	O15118-1.2	D1005C	Pathogenic	0.954
NPC1	O15118-1.2	D1005E	Pathogenic	0.848
NPC1	O15118-1.2	D1005F	Pathogenic	0.953
NPC1	O15118-1.2	D1005G	Pathogenic	0.944
NPC1	O15118-1.2	D1005H	Pathogenic	0.936
NPC1	O15118-1.2	D1005I	Pathogenic	0.949
NPC1	O15118-1.2	D1005K	Pathogenic	0.953
NPC1	O15118-1.2	D1005L	Pathogenic	0.966
NPC1	O15118-1.2	D1005M	Pathogenic	0.958
NPC1	O15118-1.2	D1005N	Pathogenic	0.882
NPC1	O15118-1.2	D1005P	Pathogenic	0.911
NPC1	O15118-1.2	D1005Q	Pathogenic	0.916
NPC1	O15118-1.2	D1005R	Pathogenic	0.97
NPC1	O15118-1.2	D1005S	Pathogenic	0.908
NPC1	O15118-1.2	D1005T	Pathogenic	0.923
NPC1	O15118-1.2	D1005V	Pathogenic	0.953
NPC1	O15118-1.2	D1005W	Pathogenic	0.968
NPC1	O15118-1.2	D1005Y	Pathogenic	0.965
NPC1	O15118-1.2	N1006A	Pathogenic	0.92
NPC1	O15118-1.2	N1006C	Pathogenic	0.924
NPC1	O15118-1.2	N1006D	Pathogenic	0.8
NPC1	O15118-1.2	N1006E	Pathogenic	0.866
NPC1	O15118-1.2	N1006F	Pathogenic	0.917
NPC1	O15118-1.2	N1006G	Pathogenic	0.869
NPC1	O15118-1.2	N1006H	Pathogenic	0.787
NPC1	O15118-1.2	N1006I	Pathogenic	0.911
NPC1	O15118-1.2	N1006K	Pathogenic	0.871
NPC1	O15118-1.2	N1006L	Pathogenic	0.914
NPC1	O15118-1.2	N1006M	Pathogenic	0.894
NPC1	O15118-1.2	N1006P	Pathogenic	0.898
NPC1	O15118-1.2	N1006Q	Pathogenic	0.856
NPC1	O15118-1.2	N1006R	Pathogenic	0.879
NPC1	O15118-1.2	N1006S	Pathogenic	0.797
NPC1	O15118-1.2	N1006T	Pathogenic	0.823
NPC1	O15118-1.2	N1006V	Pathogenic	0.917
NPC1	O15118-1.2	N1006W	Pathogenic	0.943
NPC1	O15118-1.2	N1006Y	Pathogenic	0.911
NPC1	O15118-1.2	P1007A	Pathogenic	0.964
NPC1	O15118-1.2	P1007C	Pathogenic	0.982
NPC1	O15118-1.2	P1007D	Pathogenic	0.943
NPC1	O15118-1.2	P1007E	Pathogenic	0.951
NPC1	O15118-1.2	P1007F	Pathogenic	0.988
NPC1	O15118-1.2	P1007G	Pathogenic	0.976
NPC1	O15118-1.2	P1007H	Pathogenic	0.975
NPC1	O15118-1.2	P1007I	Pathogenic	0.98
NPC1	O15118-1.2	P1007K	Pathogenic	0.953
NPC1	O15118-1.2	P1007L	Pathogenic	0.981
NPC1	O15118-1.2	P1007M	Pathogenic	0.976
NPC1	O15118-1.2	P1007N	Pathogenic	0.964
NPC1	O15118-1.2	P1007Q	Pathogenic	0.958
NPC1	O15118-1.2	P1007R	Pathogenic	0.97
NPC1	O15118-1.2	P1007S	Pathogenic	0.959
NPC1	O15118-1.2	P1007T	Pathogenic	0.959
NPC1	O15118-1.2	P1007V	Pathogenic	0.974
NPC1	O15118-1.2	P1007W	Pathogenic	0.988
NPC1	O15118-1.2	P1007Y	Pathogenic	0.987
NPC1	O15118-1.2	N1008A	Pathogenic	0.689
NPC1	O15118-1.2	N1008C	Pathogenic	0.699
NPC1	O15118-1.2	N1008D	Neutral	0.435
NPC1	O15118-1.2	N1008E	Pathogenic	0.554
NPC1	O15118-1.2	N1008F	Pathogenic	0.679
NPC1	O15118-1.2	N1008G	Pathogenic	0.56
NPC1	O15118-1.2	N1008H	Neutral	0.415
NPC1	O15118-1.2	N1008I	Pathogenic	0.663
NPC1	O15118-1.2	N1008K	Pathogenic	0.564
NPC1	O15118-1.2	N1008L	Pathogenic	0.671
NPC1	O15118-1.2	N1008M	Pathogenic	0.618
NPC1	O15118-1.2	N1008P	Pathogenic	0.627
NPC1	O15118-1.2	N1008Q	Pathogenic	0.533
NPC1	O15118-1.2	N1008R	Pathogenic	0.582
NPC1	O15118-1.2	N1008S	Neutral	0.43
NPC1	O15118-1.2	N1008T	Neutral	0.471
NPC1	O15118-1.2	N1008V	Pathogenic	0.681
NPC1	O15118-1.2	N1008W	Pathogenic	0.76
NPC1	O15118-1.2	N1008Y	Pathogenic	0.663
NPC1	O15118-1.2	P1009A	Neutral	0.337
NPC1	O15118-1.2	P1009C	Pathogenic	0.507
NPC1	O15118-1.2	P1009D	Neutral	0.237
NPC1	O15118-1.2	P1009E	Neutral	0.266
NPC1	O15118-1.2	P1009F	Pathogenic	0.597
NPC1	O15118-1.2	P1009G	Neutral	0.431
NPC1	O15118-1.2	P1009H	Neutral	0.421
NPC1	O15118-1.2	P1009I	Neutral	0.484
NPC1	O15118-1.2	P1009K	Neutral	0.274
NPC1	O15118-1.2	P1009L	Neutral	0.493
NPC1	O15118-1.2	P1009M	Neutral	0.436
NPC1	O15118-1.2	P1009N	Neutral	0.333
NPC1	O15118-1.2	P1009Q	Neutral	0.3
NPC1	O15118-1.2	P1009R	Neutral	0.374
NPC1	O15118-1.2	P1009S	Neutral	0.304
NPC1	O15118-1.2	P1009T	Neutral	0.307
NPC1	O15118-1.2	P1009V	Neutral	0.409
NPC1	O15118-1.2	P1009W	Pathogenic	0.601
NPC1	O15118-1.2	P1009Y	Pathogenic	0.579
NPC1	O15118-1.2	K1010A	Pathogenic	0.552
NPC1	O15118-1.2	K1010C	Pathogenic	0.655
NPC1	O15118-1.2	K1010D	Pathogenic	0.604
NPC1	O15118-1.2	K1010E	Neutral	0.377
NPC1	O15118-1.2	K1010F	Pathogenic	0.52
NPC1	O15118-1.2	K1010G	Pathogenic	0.693
NPC1	O15118-1.2	K1010H	Neutral	0.49
NPC1	O15118-1.2	K1010I	Pathogenic	0.535
NPC1	O15118-1.2	K1010L	Neutral	0.447
NPC1	O15118-1.2	K1010M	Neutral	0.391
NPC1	O15118-1.2	K1010N	Neutral	0.488
NPC1	O15118-1.2	K1010P	Neutral	0.484
NPC1	O15118-1.2	K1010Q	Neutral	0.338
NPC1	O15118-1.2	K1010R	Neutral	0.299
NPC1	O15118-1.2	K1010S	Neutral	0.476
NPC1	O15118-1.2	K1010T	Pathogenic	0.518
NPC1	O15118-1.2	K1010V	Pathogenic	0.516
NPC1	O15118-1.2	K1010W	Pathogenic	0.524
NPC1	O15118-1.2	K1010Y	Pathogenic	0.501
NPC1	O15118-1.2	C1011A	Pathogenic	0.95
NPC1	O15118-1.2	C1011D	Pathogenic	0.975
NPC1	O15118-1.2	C1011E	Pathogenic	0.985
NPC1	O15118-1.2	C1011F	Pathogenic	0.979
NPC1	O15118-1.2	C1011G	Pathogenic	0.984
NPC1	O15118-1.2	C1011H	Pathogenic	0.984
NPC1	O15118-1.2	C1011I	Pathogenic	0.968
NPC1	O15118-1.2	C1011K	Pathogenic	0.979
NPC1	O15118-1.2	C1011L	Pathogenic	0.969
NPC1	O15118-1.2	C1011M	Pathogenic	0.973
NPC1	O15118-1.2	C1011N	Pathogenic	0.977
NPC1	O15118-1.2	C1011P	Pathogenic	0.985
NPC1	O15118-1.2	C1011Q	Pathogenic	0.982
NPC1	O15118-1.2	C1011R	Pathogenic	0.981
NPC1	O15118-1.2	C1011S	Pathogenic	0.96
NPC1	O15118-1.2	C1011T	Pathogenic	0.963
NPC1	O15118-1.2	C1011V	Pathogenic	0.97
NPC1	O15118-1.2	C1011W	Pathogenic	0.98
NPC1	O15118-1.2	C1011Y	Pathogenic	0.985
NPC1	O15118-1.2	G1012A	Pathogenic	0.575
NPC1	O15118-1.2	G1012C	Pathogenic	0.794
NPC1	O15118-1.2	G1012D	Pathogenic	0.664
NPC1	O15118-1.2	G1012E	Pathogenic	0.772
NPC1	O15118-1.2	G1012F	Pathogenic	0.799
NPC1	O15118-1.2	G1012H	Pathogenic	0.809
NPC1	O15118-1.2	G1012I	Pathogenic	0.845
NPC1	O15118-1.2	G1012K	Pathogenic	0.779
NPC1	O15118-1.2	G1012L	Pathogenic	0.849
NPC1	O15118-1.2	G1012M	Pathogenic	0.817
NPC1	O15118-1.2	G1012N	Pathogenic	0.594
NPC1	O15118-1.2	G1012P	Pathogenic	0.746
NPC1	O15118-1.2	G1012Q	Pathogenic	0.8
NPC1	O15118-1.2	G1012R	Pathogenic	0.791
NPC1	O15118-1.2	G1012S	Pathogenic	0.606
NPC1	O15118-1.2	G1012T	Pathogenic	0.777
NPC1	O15118-1.2	G1012V	Pathogenic	0.8
NPC1	O15118-1.2	G1012W	Pathogenic	0.733
NPC1	O15118-1.2	G1012Y	Pathogenic	0.844
NPC1	O15118-1.2	K1013A	Pathogenic	0.962
NPC1	O15118-1.2	K1013C	Pathogenic	0.975
NPC1	O15118-1.2	K1013D	Pathogenic	0.969
NPC1	O15118-1.2	K1013E	Pathogenic	0.925
NPC1	O15118-1.2	K1013F	Pathogenic	0.957
NPC1	O15118-1.2	K1013G	Pathogenic	0.979
NPC1	O15118-1.2	K1013H	Pathogenic	0.952
NPC1	O15118-1.2	K1013I	Pathogenic	0.959
NPC1	O15118-1.2	K1013L	Pathogenic	0.943
NPC1	O15118-1.2	K1013M	Pathogenic	0.929
NPC1	O15118-1.2	K1013N	Pathogenic	0.951
NPC1	O15118-1.2	K1013P	Pathogenic	0.95
NPC1	O15118-1.2	K1013Q	Pathogenic	0.913
NPC1	O15118-1.2	K1013R	Pathogenic	0.897
NPC1	O15118-1.2	K1013S	Pathogenic	0.949
NPC1	O15118-1.2	K1013T	Pathogenic	0.956
NPC1	O15118-1.2	K1013V	Pathogenic	0.956
NPC1	O15118-1.2	K1013W	Pathogenic	0.957
NPC1	O15118-1.2	K1013Y	Pathogenic	0.954
NPC1	O15118-1.2	G1014A	Pathogenic	0.859
NPC1	O15118-1.2	G1014C	Pathogenic	0.946
NPC1	O15118-1.2	G1014D	Pathogenic	0.899
NPC1	O15118-1.2	G1014E	Pathogenic	0.938
NPC1	O15118-1.2	G1014F	Pathogenic	0.947
NPC1	O15118-1.2	G1014H	Pathogenic	0.95
NPC1	O15118-1.2	G1014I	Pathogenic	0.961
NPC1	O15118-1.2	G1014K	Pathogenic	0.941
NPC1	O15118-1.2	G1014L	Pathogenic	0.962
NPC1	O15118-1.2	G1014M	Pathogenic	0.953
NPC1	O15118-1.2	G1014N	Pathogenic	0.868
NPC1	O15118-1.2	G1014P	Pathogenic	0.93
NPC1	O15118-1.2	G1014Q	Pathogenic	0.948
NPC1	O15118-1.2	G1014R	Pathogenic	0.945
NPC1	O15118-1.2	G1014S	Pathogenic	0.874
NPC1	O15118-1.2	G1014T	Pathogenic	0.94
NPC1	O15118-1.2	G1014V	Pathogenic	0.948
NPC1	O15118-1.2	G1014W	Pathogenic	0.925
NPC1	O15118-1.2	G1014Y	Pathogenic	0.961
NPC1	O15118-1.2	G1015A	Pathogenic	0.944
NPC1	O15118-1.2	G1015C	Pathogenic	0.979
NPC1	O15118-1.2	G1015D	Pathogenic	0.961
NPC1	O15118-1.2	G1015E	Pathogenic	0.977
NPC1	O15118-1.2	G1015F	Pathogenic	0.98
NPC1	O15118-1.2	G1015H	Pathogenic	0.981
NPC1	O15118-1.2	G1015I	Pathogenic	0.985
NPC1	O15118-1.2	G1015K	Pathogenic	0.978
NPC1	O15118-1.2	G1015L	Pathogenic	0.986
NPC1	O15118-1.2	G1015M	Pathogenic	0.982
NPC1	O15118-1.2	G1015N	Pathogenic	0.948
NPC1	O15118-1.2	G1015P	Pathogenic	0.973
NPC1	O15118-1.2	G1015Q	Pathogenic	0.98
NPC1	O15118-1.2	G1015R	Pathogenic	0.979
NPC1	O15118-1.2	G1015S	Pathogenic	0.95
NPC1	O15118-1.2	G1015T	Pathogenic	0.977
NPC1	O15118-1.2	G1015V	Pathogenic	0.98
NPC1	O15118-1.2	G1015W	Pathogenic	0.971
NPC1	O15118-1.2	G1015Y	Pathogenic	0.985
NPC1	O15118-1.2	H1016A	Pathogenic	0.975
NPC1	O15118-1.2	H1016C	Pathogenic	0.976
NPC1	O15118-1.2	H1016D	Pathogenic	0.947
NPC1	O15118-1.2	H1016E	Pathogenic	0.919
NPC1	O15118-1.2	H1016F	Pathogenic	0.929
NPC1	O15118-1.2	H1016G	Pathogenic	0.978
NPC1	O15118-1.2	H1016I	Pathogenic	0.963
NPC1	O15118-1.2	H1016K	Pathogenic	0.94
NPC1	O15118-1.2	H1016L	Pathogenic	0.965
NPC1	O15118-1.2	H1016M	Pathogenic	0.956
NPC1	O15118-1.2	H1016N	Pathogenic	0.894
NPC1	O15118-1.2	H1016P	Pathogenic	0.967
NPC1	O15118-1.2	H1016Q	Pathogenic	0.927
NPC1	O15118-1.2	H1016R	Pathogenic	0.92
NPC1	O15118-1.2	H1016S	Pathogenic	0.962
NPC1	O15118-1.2	H1016T	Pathogenic	0.971
NPC1	O15118-1.2	H1016V	Pathogenic	0.971
NPC1	O15118-1.2	H1016W	Pathogenic	0.951
NPC1	O15118-1.2	H1016Y	Pathogenic	0.849
NPC1	O15118-1.2	A1017C	Pathogenic	0.895
NPC1	O15118-1.2	A1017D	Pathogenic	0.943
NPC1	O15118-1.2	A1017E	Pathogenic	0.929
NPC1	O15118-1.2	A1017F	Pathogenic	0.95
NPC1	O15118-1.2	A1017G	Pathogenic	0.906
NPC1	O15118-1.2	A1017H	Pathogenic	0.963
NPC1	O15118-1.2	A1017I	Pathogenic	0.923
NPC1	O15118-1.2	A1017K	Pathogenic	0.932
NPC1	O15118-1.2	A1017L	Pathogenic	0.925
NPC1	O15118-1.2	A1017M	Pathogenic	0.935
NPC1	O15118-1.2	A1017N	Pathogenic	0.948
NPC1	O15118-1.2	A1017P	Pathogenic	0.933
NPC1	O15118-1.2	A1017Q	Pathogenic	0.94
NPC1	O15118-1.2	A1017R	Pathogenic	0.936
NPC1	O15118-1.2	A1017S	Pathogenic	0.856
NPC1	O15118-1.2	A1017T	Pathogenic	0.916
NPC1	O15118-1.2	A1017V	Pathogenic	0.898
NPC1	O15118-1.2	A1017W	Pathogenic	0.966
NPC1	O15118-1.2	A1017Y	Pathogenic	0.963
NPC1	O15118-1.2	A1018C	Pathogenic	0.919
NPC1	O15118-1.2	A1018D	Pathogenic	0.957
NPC1	O15118-1.2	A1018E	Pathogenic	0.946
NPC1	O15118-1.2	A1018F	Pathogenic	0.962
NPC1	O15118-1.2	A1018G	Pathogenic	0.928
NPC1	O15118-1.2	A1018H	Pathogenic	0.972
NPC1	O15118-1.2	A1018I	Pathogenic	0.941
NPC1	O15118-1.2	A1018K	Pathogenic	0.948
NPC1	O15118-1.2	A1018L	Pathogenic	0.943
NPC1	O15118-1.2	A1018M	Pathogenic	0.951
NPC1	O15118-1.2	A1018N	Pathogenic	0.96
NPC1	O15118-1.2	A1018P	Pathogenic	0.949
NPC1	O15118-1.2	A1018Q	Pathogenic	0.954
NPC1	O15118-1.2	A1018R	Pathogenic	0.952
NPC1	O15118-1.2	A1018S	Pathogenic	0.889
NPC1	O15118-1.2	A1018T	Pathogenic	0.936
NPC1	O15118-1.2	A1018V	Pathogenic	0.922
NPC1	O15118-1.2	A1018W	Pathogenic	0.974
NPC1	O15118-1.2	A1018Y	Pathogenic	0.972
NPC1	O15118-1.2	Y1019A	Pathogenic	0.978
NPC1	O15118-1.2	Y1019C	Pathogenic	0.98
NPC1	O15118-1.2	Y1019D	Pathogenic	0.976
NPC1	O15118-1.2	Y1019E	Pathogenic	0.962
NPC1	O15118-1.2	Y1019F	Pathogenic	0.804
NPC1	O15118-1.2	Y1019G	Pathogenic	0.985
NPC1	O15118-1.2	Y1019H	Pathogenic	0.87
NPC1	O15118-1.2	Y1019I	Pathogenic	0.953
NPC1	O15118-1.2	Y1019K	Pathogenic	0.951
NPC1	O15118-1.2	Y1019L	Pathogenic	0.955
NPC1	O15118-1.2	Y1019M	Pathogenic	0.961
NPC1	O15118-1.2	Y1019N	Pathogenic	0.966
NPC1	O15118-1.2	Y1019P	Pathogenic	0.985
NPC1	O15118-1.2	Y1019Q	Pathogenic	0.951
NPC1	O15118-1.2	Y1019R	Pathogenic	0.951
NPC1	O15118-1.2	Y1019S	Pathogenic	0.975
NPC1	O15118-1.2	Y1019T	Pathogenic	0.974
NPC1	O15118-1.2	Y1019V	Pathogenic	0.965
NPC1	O15118-1.2	Y1019W	Pathogenic	0.851
NPC1	O15118-1.2	S1020A	Neutral	0.332
NPC1	O15118-1.2	S1020C	Neutral	0.473
NPC1	O15118-1.2	S1020D	Neutral	0.409
NPC1	O15118-1.2	S1020E	Neutral	0.446
NPC1	O15118-1.2	S1020F	Pathogenic	0.576
NPC1	O15118-1.2	S1020G	Neutral	0.476
NPC1	O15118-1.2	S1020H	Pathogenic	0.591
NPC1	O15118-1.2	S1020I	Pathogenic	0.558
NPC1	O15118-1.2	S1020K	Neutral	0.456
NPC1	O15118-1.2	S1020L	Pathogenic	0.567
NPC1	O15118-1.2	S1020M	Pathogenic	0.51
NPC1	O15118-1.2	S1020N	Neutral	0.339
NPC1	O15118-1.2	S1020P	Pathogenic	0.501
NPC1	O15118-1.2	S1020Q	Neutral	0.488
NPC1	O15118-1.2	S1020R	Pathogenic	0.571
NPC1	O15118-1.2	S1020T	Neutral	0.355
NPC1	O15118-1.2	S1020V	Pathogenic	0.578
NPC1	O15118-1.2	S1020W	Pathogenic	0.67
NPC1	O15118-1.2	S1020Y	Pathogenic	0.65
NPC1	O15118-1.2	S1021A	Neutral	0.259
NPC1	O15118-1.2	S1021C	Neutral	0.387
NPC1	O15118-1.2	S1021D	Neutral	0.327
NPC1	O15118-1.2	S1021E	Neutral	0.362
NPC1	O15118-1.2	S1021F	Neutral	0.489
NPC1	O15118-1.2	S1021G	Neutral	0.39
NPC1	O15118-1.2	S1021H	Pathogenic	0.504
NPC1	O15118-1.2	S1021I	Neutral	0.471
NPC1	O15118-1.2	S1021K	Neutral	0.371
NPC1	O15118-1.2	S1021L	Neutral	0.479
NPC1	O15118-1.2	S1021M	Neutral	0.423
NPC1	O15118-1.2	S1021N	Neutral	0.265
NPC1	O15118-1.2	S1021P	Neutral	0.414
NPC1	O15118-1.2	S1021Q	Neutral	0.402
NPC1	O15118-1.2	S1021R	Neutral	0.483
NPC1	O15118-1.2	S1021T	Neutral	0.279
NPC1	O15118-1.2	S1021V	Neutral	0.491
NPC1	O15118-1.2	S1021W	Pathogenic	0.588
NPC1	O15118-1.2	S1021Y	Pathogenic	0.566
NPC1	O15118-1.2	A1022C	Pathogenic	0.773
NPC1	O15118-1.2	A1022D	Pathogenic	0.869
NPC1	O15118-1.2	A1022E	Pathogenic	0.84
NPC1	O15118-1.2	A1022F	Pathogenic	0.883
NPC1	O15118-1.2	A1022G	Pathogenic	0.794
NPC1	O15118-1.2	A1022H	Pathogenic	0.913
NPC1	O15118-1.2	A1022I	Pathogenic	0.827
NPC1	O15118-1.2	A1022K	Pathogenic	0.846
NPC1	O15118-1.2	A1022L	Pathogenic	0.832
NPC1	O15118-1.2	A1022M	Pathogenic	0.853
NPC1	O15118-1.2	A1022N	Pathogenic	0.879
NPC1	O15118-1.2	A1022P	Pathogenic	0.848
NPC1	O15118-1.2	A1022Q	Pathogenic	0.862
NPC1	O15118-1.2	A1022R	Pathogenic	0.855
NPC1	O15118-1.2	A1022S	Pathogenic	0.705
NPC1	O15118-1.2	A1022T	Pathogenic	0.814
NPC1	O15118-1.2	A1022V	Pathogenic	0.779
NPC1	O15118-1.2	A1022W	Pathogenic	0.919
NPC1	O15118-1.2	A1022Y	Pathogenic	0.912
NPC1	O15118-1.2	V1023A	Pathogenic	0.881
NPC1	O15118-1.2	V1023C	Pathogenic	0.924
NPC1	O15118-1.2	V1023D	Pathogenic	0.934
NPC1	O15118-1.2	V1023E	Pathogenic	0.905
NPC1	O15118-1.2	V1023F	Pathogenic	0.921
NPC1	O15118-1.2	V1023G	Pathogenic	0.96
NPC1	O15118-1.2	V1023H	Pathogenic	0.95
NPC1	O15118-1.2	V1023I	Pathogenic	0.698
NPC1	O15118-1.2	V1023K	Pathogenic	0.908
NPC1	O15118-1.2	V1023L	Pathogenic	0.838
NPC1	O15118-1.2	V1023M	Pathogenic	0.858
NPC1	O15118-1.2	V1023N	Pathogenic	0.936
NPC1	O15118-1.2	V1023P	Pathogenic	0.941
NPC1	O15118-1.2	V1023Q	Pathogenic	0.918
NPC1	O15118-1.2	V1023R	Pathogenic	0.94
NPC1	O15118-1.2	V1023S	Pathogenic	0.932
NPC1	O15118-1.2	V1023T	Pathogenic	0.861
NPC1	O15118-1.2	V1023W	Pathogenic	0.962
NPC1	O15118-1.2	V1023Y	Pathogenic	0.93
NPC1	O15118-1.2	N1024A	Pathogenic	0.614
NPC1	O15118-1.2	N1024C	Pathogenic	0.625
NPC1	O15118-1.2	N1024D	Neutral	0.356
NPC1	O15118-1.2	N1024E	Neutral	0.472
NPC1	O15118-1.2	N1024F	Pathogenic	0.603
NPC1	O15118-1.2	N1024G	Neutral	0.478
NPC1	O15118-1.2	N1024H	Neutral	0.337
NPC1	O15118-1.2	N1024I	Pathogenic	0.586
NPC1	O15118-1.2	N1024K	Neutral	0.482
NPC1	O15118-1.2	N1024L	Pathogenic	0.594
NPC1	O15118-1.2	N1024M	Pathogenic	0.538
NPC1	O15118-1.2	N1024P	Pathogenic	0.547
NPC1	O15118-1.2	N1024Q	Neutral	0.451
NPC1	O15118-1.2	N1024R	Pathogenic	0.5
NPC1	O15118-1.2	N1024S	Neutral	0.351
NPC1	O15118-1.2	N1024T	Neutral	0.39
NPC1	O15118-1.2	N1024V	Pathogenic	0.605
NPC1	O15118-1.2	N1024W	Pathogenic	0.694
NPC1	O15118-1.2	N1024Y	Pathogenic	0.585
NPC1	O15118-1.2	I1025A	Neutral	0.338
NPC1	O15118-1.2	I1025C	Neutral	0.363
NPC1	O15118-1.2	I1025D	Neutral	0.4
NPC1	O15118-1.2	I1025E	Neutral	0.385
NPC1	O15118-1.2	I1025F	Neutral	0.301
NPC1	O15118-1.2	I1025G	Pathogenic	0.622
NPC1	O15118-1.2	I1025H	Neutral	0.433
NPC1	O15118-1.2	I1025K	Neutral	0.352
NPC1	O15118-1.2	I1025L	Neutral	0.153
NPC1	O15118-1.2	I1025M	Neutral	0.185
NPC1	O15118-1.2	I1025N	Neutral	0.407
NPC1	O15118-1.2	I1025P	Pathogenic	0.524
NPC1	O15118-1.2	I1025Q	Neutral	0.411
NPC1	O15118-1.2	I1025R	Neutral	0.369
NPC1	O15118-1.2	I1025S	Neutral	0.392
NPC1	O15118-1.2	I1025T	Neutral	0.3
NPC1	O15118-1.2	I1025V	Neutral	0.105
NPC1	O15118-1.2	I1025W	Pathogenic	0.584
NPC1	O15118-1.2	I1025Y	Neutral	0.332
NPC1	O15118-1.2	L1026A	Pathogenic	0.612
NPC1	O15118-1.2	L1026C	Pathogenic	0.638
NPC1	O15118-1.2	L1026D	Pathogenic	0.752
NPC1	O15118-1.2	L1026E	Pathogenic	0.659
NPC1	O15118-1.2	L1026F	Pathogenic	0.556
NPC1	O15118-1.2	L1026G	Pathogenic	0.836
NPC1	O15118-1.2	L1026H	Pathogenic	0.703
NPC1	O15118-1.2	L1026I	Neutral	0.35
NPC1	O15118-1.2	L1026K	Pathogenic	0.533
NPC1	O15118-1.2	L1026M	Neutral	0.323
NPC1	O15118-1.2	L1026N	Pathogenic	0.679
NPC1	O15118-1.2	L1026P	Pathogenic	0.773
NPC1	O15118-1.2	L1026Q	Pathogenic	0.594
NPC1	O15118-1.2	L1026R	Pathogenic	0.551
NPC1	O15118-1.2	L1026S	Pathogenic	0.666
NPC1	O15118-1.2	L1026T	Pathogenic	0.57
NPC1	O15118-1.2	L1026V	Neutral	0.44
NPC1	O15118-1.2	L1026W	Pathogenic	0.734
NPC1	O15118-1.2	L1026Y	Pathogenic	0.606
NPC1	O15118-1.2	L1027A	Neutral	0.21
NPC1	O15118-1.2	L1027C	Neutral	0.229
NPC1	O15118-1.2	L1027D	Neutral	0.338
NPC1	O15118-1.2	L1027E	Neutral	0.246
NPC1	O15118-1.2	L1027F	Neutral	0.174
NPC1	O15118-1.2	L1027G	Neutral	0.461
NPC1	O15118-1.2	L1027H	Neutral	0.285
NPC1	O15118-1.2	L1027I	Neutral	0.083
NPC1	O15118-1.2	L1027K	Neutral	0.161
NPC1	O15118-1.2	L1027M	Neutral	0.074
NPC1	O15118-1.2	L1027N	Neutral	0.263
NPC1	O15118-1.2	L1027P	Neutral	0.364
NPC1	O15118-1.2	L1027Q	Neutral	0.198
NPC1	O15118-1.2	L1027R	Neutral	0.171
NPC1	O15118-1.2	L1027S	Neutral	0.252
NPC1	O15118-1.2	L1027T	Neutral	0.182
NPC1	O15118-1.2	L1027V	Neutral	0.117
NPC1	O15118-1.2	L1027W	Neutral	0.317
NPC1	O15118-1.2	L1027Y	Neutral	0.206
NPC1	O15118-1.2	G1028A	Neutral	0.161
NPC1	O15118-1.2	G1028C	Neutral	0.354
NPC1	O15118-1.2	G1028D	Neutral	0.219
NPC1	O15118-1.2	G1028E	Neutral	0.324
NPC1	O15118-1.2	G1028F	Neutral	0.361
NPC1	O15118-1.2	G1028H	Neutral	0.375
NPC1	O15118-1.2	G1028I	Neutral	0.436
NPC1	O15118-1.2	G1028K	Neutral	0.333
NPC1	O15118-1.2	G1028L	Neutral	0.444
NPC1	O15118-1.2	G1028M	Neutral	0.388
NPC1	O15118-1.2	G1028N	Neutral	0.172
NPC1	O15118-1.2	G1028P	Neutral	0.294
NPC1	O15118-1.2	G1028Q	Neutral	0.363
NPC1	O15118-1.2	G1028R	Neutral	0.35
NPC1	O15118-1.2	G1028S	Neutral	0.179
NPC1	O15118-1.2	G1028T	Neutral	0.331
NPC1	O15118-1.2	G1028V	Neutral	0.363
NPC1	O15118-1.2	G1028W	Neutral	0.28
NPC1	O15118-1.2	G1028Y	Neutral	0.435
NPC1	O15118-1.2	H1029A	Pathogenic	0.618
NPC1	O15118-1.2	H1029C	Pathogenic	0.629
NPC1	O15118-1.2	H1029D	Neutral	0.428
NPC1	O15118-1.2	H1029E	Neutral	0.323
NPC1	O15118-1.2	H1029F	Neutral	0.354
NPC1	O15118-1.2	H1029G	Pathogenic	0.648
NPC1	O15118-1.2	H1029I	Pathogenic	0.525
NPC1	O15118-1.2	H1029K	Neutral	0.396
NPC1	O15118-1.2	H1029L	Pathogenic	0.533
NPC1	O15118-1.2	H1029M	Neutral	0.476
NPC1	O15118-1.2	H1029N	Neutral	0.262
NPC1	O15118-1.2	H1029P	Pathogenic	0.551
NPC1	O15118-1.2	H1029Q	Neutral	0.347
NPC1	O15118-1.2	H1029R	Neutral	0.324
NPC1	O15118-1.2	H1029S	Pathogenic	0.516
NPC1	O15118-1.2	H1029T	Pathogenic	0.585
NPC1	O15118-1.2	H1029V	Pathogenic	0.583
NPC1	O15118-1.2	H1029W	Neutral	0.45
NPC1	O15118-1.2	H1029Y	Neutral	0.19
NPC1	O15118-1.2	G1030A	Neutral	0.083
NPC1	O15118-1.2	G1030C	Neutral	0.206
NPC1	O15118-1.2	G1030D	Neutral	0.117
NPC1	O15118-1.2	G1030E	Neutral	0.185
NPC1	O15118-1.2	G1030F	Neutral	0.211
NPC1	O15118-1.2	G1030H	Neutral	0.221
NPC1	O15118-1.2	G1030I	Neutral	0.268
NPC1	O15118-1.2	G1030K	Neutral	0.192
NPC1	O15118-1.2	G1030L	Neutral	0.275
NPC1	O15118-1.2	G1030M	Neutral	0.231
NPC1	O15118-1.2	G1030N	Neutral	0.09
NPC1	O15118-1.2	G1030P	Neutral	0.165
NPC1	O15118-1.2	G1030Q	Neutral	0.212
NPC1	O15118-1.2	G1030R	Neutral	0.203
NPC1	O15118-1.2	G1030S	Neutral	0.094
NPC1	O15118-1.2	G1030T	Neutral	0.19
NPC1	O15118-1.2	G1030V	Neutral	0.212
NPC1	O15118-1.2	G1030W	Neutral	0.156
NPC1	O15118-1.2	G1030Y	Neutral	0.267
NPC1	O15118-1.2	T1031A	Neutral	0.414
NPC1	O15118-1.2	T1031C	Neutral	0.426
NPC1	O15118-1.2	T1031D	Neutral	0.394
NPC1	O15118-1.2	T1031E	Neutral	0.425
NPC1	O15118-1.2	T1031F	Pathogenic	0.508
NPC1	O15118-1.2	T1031G	Pathogenic	0.616
NPC1	O15118-1.2	T1031H	Pathogenic	0.598
NPC1	O15118-1.2	T1031I	Neutral	0.395
NPC1	O15118-1.2	T1031K	Neutral	0.435
NPC1	O15118-1.2	T1031L	Neutral	0.403
NPC1	O15118-1.2	T1031M	Neutral	0.441
NPC1	O15118-1.2	T1031N	Neutral	0.32
NPC1	O15118-1.2	T1031P	Neutral	0.441
NPC1	O15118-1.2	T1031Q	Neutral	0.467
NPC1	O15118-1.2	T1031R	Neutral	0.453
NPC1	O15118-1.2	T1031S	Neutral	0.3
NPC1	O15118-1.2	T1031V	Neutral	0.325
NPC1	O15118-1.2	T1031W	Pathogenic	0.512
NPC1	O15118-1.2	T1031Y	Pathogenic	0.585
NPC1	O15118-1.2	R1032A	Neutral	0.11
NPC1	O15118-1.2	R1032C	Neutral	0.16
NPC1	O15118-1.2	R1032D	Neutral	0.184
NPC1	O15118-1.2	R1032E	Neutral	0.082
NPC1	O15118-1.2	R1032F	Neutral	0.098
NPC1	O15118-1.2	R1032G	Neutral	0.184
NPC1	O15118-1.2	R1032H	Neutral	0.061
NPC1	O15118-1.2	R1032I	Neutral	0.103
NPC1	O15118-1.2	R1032K	Neutral	0.038
NPC1	O15118-1.2	R1032L	Neutral	0.075
NPC1	O15118-1.2	R1032M	Neutral	0.061
NPC1	O15118-1.2	R1032N	Neutral	0.087
NPC1	O15118-1.2	R1032P	Neutral	0.121
NPC1	O15118-1.2	R1032Q	Neutral	0.049
NPC1	O15118-1.2	R1032S	Neutral	0.118
NPC1	O15118-1.2	R1032T	Neutral	0.097
NPC1	O15118-1.2	R1032V	Neutral	0.136
NPC1	O15118-1.2	R1032W	Neutral	0.086
NPC1	O15118-1.2	R1032Y	Neutral	0.086
NPC1	O15118-1.2	V1033A	Pathogenic	0.746
NPC1	O15118-1.2	V1033C	Pathogenic	0.828
NPC1	O15118-1.2	V1033D	Pathogenic	0.849
NPC1	O15118-1.2	V1033E	Pathogenic	0.79
NPC1	O15118-1.2	V1033F	Pathogenic	0.821
NPC1	O15118-1.2	V1033G	Pathogenic	0.904
NPC1	O15118-1.2	V1033H	Pathogenic	0.883
NPC1	O15118-1.2	V1033I	Neutral	0.478
NPC1	O15118-1.2	V1033K	Pathogenic	0.797
NPC1	O15118-1.2	V1033L	Pathogenic	0.672
NPC1	O15118-1.2	V1033M	Pathogenic	0.705
NPC1	O15118-1.2	V1033N	Pathogenic	0.853
NPC1	O15118-1.2	V1033P	Pathogenic	0.863
NPC1	O15118-1.2	V1033Q	Pathogenic	0.817
NPC1	O15118-1.2	V1033R	Pathogenic	0.861
NPC1	O15118-1.2	V1033S	Pathogenic	0.845
NPC1	O15118-1.2	V1033T	Pathogenic	0.711
NPC1	O15118-1.2	V1033W	Pathogenic	0.91
NPC1	O15118-1.2	V1033Y	Pathogenic	0.841
NPC1	O15118-1.2	G1034A	Pathogenic	0.726
NPC1	O15118-1.2	G1034C	Pathogenic	0.883
NPC1	O15118-1.2	G1034D	Pathogenic	0.795
NPC1	O15118-1.2	G1034E	Pathogenic	0.869
NPC1	O15118-1.2	G1034F	Pathogenic	0.886
NPC1	O15118-1.2	G1034H	Pathogenic	0.892
NPC1	O15118-1.2	G1034I	Pathogenic	0.914
NPC1	O15118-1.2	G1034K	Pathogenic	0.874
NPC1	O15118-1.2	G1034L	Pathogenic	0.917
NPC1	O15118-1.2	G1034M	Pathogenic	0.898
NPC1	O15118-1.2	G1034N	Pathogenic	0.742
NPC1	O15118-1.2	G1034P	Pathogenic	0.852
NPC1	O15118-1.2	G1034Q	Pathogenic	0.887
NPC1	O15118-1.2	G1034R	Pathogenic	0.881
NPC1	O15118-1.2	G1034S	Pathogenic	0.751
NPC1	O15118-1.2	G1034T	Pathogenic	0.872
NPC1	O15118-1.2	G1034V	Pathogenic	0.887
NPC1	O15118-1.2	G1034W	Pathogenic	0.843
NPC1	O15118-1.2	G1034Y	Pathogenic	0.914
NPC1	O15118-1.2	A1035C	Pathogenic	0.893
NPC1	O15118-1.2	A1035D	Pathogenic	0.942
NPC1	O15118-1.2	A1035E	Pathogenic	0.928
NPC1	O15118-1.2	A1035F	Pathogenic	0.949
NPC1	O15118-1.2	A1035G	Pathogenic	0.904
NPC1	O15118-1.2	A1035H	Pathogenic	0.963
NPC1	O15118-1.2	A1035I	Pathogenic	0.921
NPC1	O15118-1.2	A1035K	Pathogenic	0.93
NPC1	O15118-1.2	A1035L	Pathogenic	0.924
NPC1	O15118-1.2	A1035M	Pathogenic	0.934
NPC1	O15118-1.2	A1035N	Pathogenic	0.946
NPC1	O15118-1.2	A1035P	Pathogenic	0.932
NPC1	O15118-1.2	A1035Q	Pathogenic	0.938
NPC1	O15118-1.2	A1035R	Pathogenic	0.935
NPC1	O15118-1.2	A1035S	Pathogenic	0.854
NPC1	O15118-1.2	A1035T	Pathogenic	0.914
NPC1	O15118-1.2	A1035V	Pathogenic	0.896
NPC1	O15118-1.2	A1035W	Pathogenic	0.965
NPC1	O15118-1.2	A1035Y	Pathogenic	0.962
NPC1	O15118-1.2	T1036A	Pathogenic	0.826
NPC1	O15118-1.2	T1036C	Pathogenic	0.833
NPC1	O15118-1.2	T1036D	Pathogenic	0.814
NPC1	O15118-1.2	T1036E	Pathogenic	0.832
NPC1	O15118-1.2	T1036F	Pathogenic	0.874
NPC1	O15118-1.2	T1036G	Pathogenic	0.915
NPC1	O15118-1.2	T1036H	Pathogenic	0.909
NPC1	O15118-1.2	T1036I	Pathogenic	0.814
NPC1	O15118-1.2	T1036K	Pathogenic	0.838
NPC1	O15118-1.2	T1036L	Pathogenic	0.819
NPC1	O15118-1.2	T1036M	Pathogenic	0.841
NPC1	O15118-1.2	T1036N	Pathogenic	0.76
NPC1	O15118-1.2	T1036P	Pathogenic	0.841
NPC1	O15118-1.2	T1036Q	Pathogenic	0.855
NPC1	O15118-1.2	T1036R	Pathogenic	0.848
NPC1	O15118-1.2	T1036S	Pathogenic	0.742
NPC1	O15118-1.2	T1036V	Pathogenic	0.763
NPC1	O15118-1.2	T1036W	Pathogenic	0.875
NPC1	O15118-1.2	T1036Y	Pathogenic	0.904
NPC1	O15118-1.2	Y1037A	Pathogenic	0.933
NPC1	O15118-1.2	Y1037C	Pathogenic	0.939
NPC1	O15118-1.2	Y1037D	Pathogenic	0.925
NPC1	O15118-1.2	Y1037E	Pathogenic	0.887
NPC1	O15118-1.2	Y1037F	Pathogenic	0.558
NPC1	O15118-1.2	Y1037G	Pathogenic	0.954
NPC1	O15118-1.2	Y1037H	Pathogenic	0.673
NPC1	O15118-1.2	Y1037I	Pathogenic	0.863
NPC1	O15118-1.2	Y1037K	Pathogenic	0.857
NPC1	O15118-1.2	Y1037L	Pathogenic	0.867
NPC1	O15118-1.2	Y1037M	Pathogenic	0.884
NPC1	O15118-1.2	Y1037N	Pathogenic	0.896
NPC1	O15118-1.2	Y1037P	Pathogenic	0.953
NPC1	O15118-1.2	Y1037Q	Pathogenic	0.857
NPC1	O15118-1.2	Y1037R	Pathogenic	0.857
NPC1	O15118-1.2	Y1037S	Pathogenic	0.923
NPC1	O15118-1.2	Y1037T	Pathogenic	0.921
NPC1	O15118-1.2	Y1037V	Pathogenic	0.896
NPC1	O15118-1.2	Y1037W	Pathogenic	0.637
NPC1	O15118-1.2	F1038A	Pathogenic	0.971
NPC1	O15118-1.2	F1038C	Pathogenic	0.974
NPC1	O15118-1.2	F1038D	Pathogenic	0.968
NPC1	O15118-1.2	F1038E	Pathogenic	0.965
NPC1	O15118-1.2	F1038G	Pathogenic	0.98
NPC1	O15118-1.2	F1038H	Pathogenic	0.94
NPC1	O15118-1.2	F1038I	Pathogenic	0.947
NPC1	O15118-1.2	F1038K	Pathogenic	0.955
NPC1	O15118-1.2	F1038L	Pathogenic	0.946
NPC1	O15118-1.2	F1038M	Pathogenic	0.937
NPC1	O15118-1.2	F1038N	Pathogenic	0.968
NPC1	O15118-1.2	F1038P	Pathogenic	0.986
NPC1	O15118-1.2	F1038Q	Pathogenic	0.969
NPC1	O15118-1.2	F1038R	Pathogenic	0.958
NPC1	O15118-1.2	F1038S	Pathogenic	0.966
NPC1	O15118-1.2	F1038T	Pathogenic	0.966
NPC1	O15118-1.2	F1038V	Pathogenic	0.961
NPC1	O15118-1.2	F1038W	Pathogenic	0.921
NPC1	O15118-1.2	F1038Y	Pathogenic	0.806
NPC1	O15118-1.2	M1039A	Pathogenic	0.969
NPC1	O15118-1.2	M1039C	Pathogenic	0.972
NPC1	O15118-1.2	M1039D	Pathogenic	0.976
NPC1	O15118-1.2	M1039E	Pathogenic	0.963
NPC1	O15118-1.2	M1039F	Pathogenic	0.948
NPC1	O15118-1.2	M1039G	Pathogenic	0.986
NPC1	O15118-1.2	M1039H	Pathogenic	0.97
NPC1	O15118-1.2	M1039I	Pathogenic	0.92
NPC1	O15118-1.2	M1039K	Pathogenic	0.939
NPC1	O15118-1.2	M1039L	Pathogenic	0.89
NPC1	O15118-1.2	M1039N	Pathogenic	0.966
NPC1	O15118-1.2	M1039P	Pathogenic	0.979
NPC1	O15118-1.2	M1039Q	Pathogenic	0.931
NPC1	O15118-1.2	M1039R	Pathogenic	0.943
NPC1	O15118-1.2	M1039S	Pathogenic	0.964
NPC1	O15118-1.2	M1039T	Pathogenic	0.963
NPC1	O15118-1.2	M1039V	Pathogenic	0.94
NPC1	O15118-1.2	M1039W	Pathogenic	0.965
NPC1	O15118-1.2	M1039Y	Pathogenic	0.968
NPC1	O15118-1.2	T1040A	Pathogenic	0.787
NPC1	O15118-1.2	T1040C	Pathogenic	0.795
NPC1	O15118-1.2	T1040D	Pathogenic	0.773
NPC1	O15118-1.2	T1040E	Pathogenic	0.795
NPC1	O15118-1.2	T1040F	Pathogenic	0.843
NPC1	O15118-1.2	T1040G	Pathogenic	0.893
NPC1	O15118-1.2	T1040H	Pathogenic	0.886
NPC1	O15118-1.2	T1040I	Pathogenic	0.773
NPC1	O15118-1.2	T1040K	Pathogenic	0.801
NPC1	O15118-1.2	T1040L	Pathogenic	0.779
NPC1	O15118-1.2	T1040M	Pathogenic	0.805
NPC1	O15118-1.2	T1040N	Pathogenic	0.711
NPC1	O15118-1.2	T1040P	Pathogenic	0.805
NPC1	O15118-1.2	T1040Q	Pathogenic	0.821
NPC1	O15118-1.2	T1040R	Pathogenic	0.813
NPC1	O15118-1.2	T1040S	Pathogenic	0.691
NPC1	O15118-1.2	T1040V	Pathogenic	0.715
NPC1	O15118-1.2	T1040W	Pathogenic	0.845
NPC1	O15118-1.2	T1040Y	Pathogenic	0.88
NPC1	O15118-1.2	Y1041A	Pathogenic	0.971
NPC1	O15118-1.2	Y1041C	Pathogenic	0.974
NPC1	O15118-1.2	Y1041D	Pathogenic	0.968
NPC1	O15118-1.2	Y1041E	Pathogenic	0.95
NPC1	O15118-1.2	Y1041F	Pathogenic	0.753
NPC1	O15118-1.2	Y1041G	Pathogenic	0.98
NPC1	O15118-1.2	Y1041H	Pathogenic	0.832
NPC1	O15118-1.2	Y1041I	Pathogenic	0.938
NPC1	O15118-1.2	Y1041K	Pathogenic	0.935
NPC1	O15118-1.2	Y1041L	Pathogenic	0.94
NPC1	O15118-1.2	Y1041M	Pathogenic	0.948
NPC1	O15118-1.2	Y1041N	Pathogenic	0.954
NPC1	O15118-1.2	Y1041P	Pathogenic	0.98
NPC1	O15118-1.2	Y1041Q	Pathogenic	0.935
NPC1	O15118-1.2	Y1041R	Pathogenic	0.935
NPC1	O15118-1.2	Y1041S	Pathogenic	0.967
NPC1	O15118-1.2	Y1041T	Pathogenic	0.966
NPC1	O15118-1.2	Y1041V	Pathogenic	0.954
NPC1	O15118-1.2	Y1041W	Pathogenic	0.809
NPC1	O15118-1.2	H1042A	Pathogenic	0.989
NPC1	O15118-1.2	H1042C	Pathogenic	0.989
NPC1	O15118-1.2	H1042D	Pathogenic	0.976
NPC1	O15118-1.2	H1042E	Pathogenic	0.963
NPC1	O15118-1.2	H1042F	Pathogenic	0.967
NPC1	O15118-1.2	H1042G	Pathogenic	0.99
NPC1	O15118-1.2	H1042I	Pathogenic	0.983
NPC1	O15118-1.2	H1042K	Pathogenic	0.972
NPC1	O15118-1.2	H1042L	Pathogenic	0.984
NPC1	O15118-1.2	H1042M	Pathogenic	0.98
NPC1	O15118-1.2	H1042N	Pathogenic	0.95
NPC1	O15118-1.2	H1042P	Pathogenic	0.985
NPC1	O15118-1.2	H1042Q	Pathogenic	0.966
NPC1	O15118-1.2	H1042R	Pathogenic	0.963
NPC1	O15118-1.2	H1042S	Pathogenic	0.983
NPC1	O15118-1.2	H1042T	Pathogenic	0.987
NPC1	O15118-1.2	H1042V	Pathogenic	0.987
NPC1	O15118-1.2	H1042W	Pathogenic	0.978
NPC1	O15118-1.2	H1042Y	Pathogenic	0.927
NPC1	O15118-1.2	T1043A	Pathogenic	0.903
NPC1	O15118-1.2	T1043C	Pathogenic	0.907
NPC1	O15118-1.2	T1043D	Pathogenic	0.895
NPC1	O15118-1.2	T1043E	Pathogenic	0.907
NPC1	O15118-1.2	T1043F	Pathogenic	0.931
NPC1	O15118-1.2	T1043G	Pathogenic	0.955
NPC1	O15118-1.2	T1043H	Pathogenic	0.951
NPC1	O15118-1.2	T1043I	Pathogenic	0.895
NPC1	O15118-1.2	T1043K	Pathogenic	0.91
NPC1	O15118-1.2	T1043L	Pathogenic	0.898
NPC1	O15118-1.2	T1043M	Pathogenic	0.912
NPC1	O15118-1.2	T1043N	Pathogenic	0.861
NPC1	O15118-1.2	T1043P	Pathogenic	0.912
NPC1	O15118-1.2	T1043Q	Pathogenic	0.92
NPC1	O15118-1.2	T1043R	Pathogenic	0.916
NPC1	O15118-1.2	T1043S	Pathogenic	0.849
NPC1	O15118-1.2	T1043V	Pathogenic	0.863
NPC1	O15118-1.2	T1043W	Pathogenic	0.932
NPC1	O15118-1.2	T1043Y	Pathogenic	0.949
NPC1	O15118-1.2	V1044A	Pathogenic	0.608
NPC1	O15118-1.2	V1044C	Pathogenic	0.718
NPC1	O15118-1.2	V1044D	Pathogenic	0.749
NPC1	O15118-1.2	V1044E	Pathogenic	0.666
NPC1	O15118-1.2	V1044F	Pathogenic	0.708
NPC1	O15118-1.2	V1044G	Pathogenic	0.833
NPC1	O15118-1.2	V1044H	Pathogenic	0.8
NPC1	O15118-1.2	V1044I	Neutral	0.326
NPC1	O15118-1.2	V1044K	Pathogenic	0.675
NPC1	O15118-1.2	V1044L	Pathogenic	0.52
NPC1	O15118-1.2	V1044M	Pathogenic	0.558
NPC1	O15118-1.2	V1044N	Pathogenic	0.754
NPC1	O15118-1.2	V1044P	Pathogenic	0.77
NPC1	O15118-1.2	V1044Q	Pathogenic	0.703
NPC1	O15118-1.2	V1044R	Pathogenic	0.767
NPC1	O15118-1.2	V1044S	Pathogenic	0.743
NPC1	O15118-1.2	V1044T	Pathogenic	0.566
NPC1	O15118-1.2	V1044W	Pathogenic	0.842
NPC1	O15118-1.2	V1044Y	Pathogenic	0.737
NPC1	O15118-1.2	L1045A	Pathogenic	0.897
NPC1	O15118-1.2	L1045C	Pathogenic	0.906
NPC1	O15118-1.2	L1045D	Pathogenic	0.943
NPC1	O15118-1.2	L1045E	Pathogenic	0.914
NPC1	O15118-1.2	L1045F	Pathogenic	0.873
NPC1	O15118-1.2	L1045G	Pathogenic	0.965
NPC1	O15118-1.2	L1045H	Pathogenic	0.929
NPC1	O15118-1.2	L1045I	Pathogenic	0.748
NPC1	O15118-1.2	L1045K	Pathogenic	0.862
NPC1	O15118-1.2	L1045M	Pathogenic	0.724
NPC1	O15118-1.2	L1045N	Pathogenic	0.921
NPC1	O15118-1.2	L1045P	Pathogenic	0.949
NPC1	O15118-1.2	L1045Q	Pathogenic	0.89
NPC1	O15118-1.2	L1045R	Pathogenic	0.871
NPC1	O15118-1.2	L1045S	Pathogenic	0.916
NPC1	O15118-1.2	L1045T	Pathogenic	0.879
NPC1	O15118-1.2	L1045V	Pathogenic	0.812
NPC1	O15118-1.2	L1045W	Pathogenic	0.938
NPC1	O15118-1.2	L1045Y	Pathogenic	0.894
NPC1	O15118-1.2	Q1046A	Pathogenic	0.699
NPC1	O15118-1.2	Q1046C	Pathogenic	0.781
NPC1	O15118-1.2	Q1046D	Pathogenic	0.575
NPC1	O15118-1.2	Q1046E	Neutral	0.37
NPC1	O15118-1.2	Q1046F	Pathogenic	0.724
NPC1	O15118-1.2	Q1046G	Pathogenic	0.809
NPC1	O15118-1.2	Q1046H	Pathogenic	0.563
NPC1	O15118-1.2	Q1046I	Pathogenic	0.709
NPC1	O15118-1.2	Q1046K	Neutral	0.458
NPC1	O15118-1.2	Q1046L	Pathogenic	0.632
NPC1	O15118-1.2	Q1046M	Neutral	0.481
NPC1	O15118-1.2	Q1046N	Pathogenic	0.581
NPC1	O15118-1.2	Q1046P	Pathogenic	0.638
NPC1	O15118-1.2	Q1046R	Neutral	0.476
NPC1	O15118-1.2	Q1046S	Pathogenic	0.63
NPC1	O15118-1.2	Q1046T	Pathogenic	0.668
NPC1	O15118-1.2	Q1046V	Pathogenic	0.667
NPC1	O15118-1.2	Q1046W	Pathogenic	0.644
NPC1	O15118-1.2	Q1046Y	Pathogenic	0.623
NPC1	O15118-1.2	T1047A	Pathogenic	0.719
NPC1	O15118-1.2	T1047C	Pathogenic	0.729
NPC1	O15118-1.2	T1047D	Pathogenic	0.702
NPC1	O15118-1.2	T1047E	Pathogenic	0.728
NPC1	O15118-1.2	T1047F	Pathogenic	0.789
NPC1	O15118-1.2	T1047G	Pathogenic	0.853
NPC1	O15118-1.2	T1047H	Pathogenic	0.843
NPC1	O15118-1.2	T1047I	Pathogenic	0.703
NPC1	O15118-1.2	T1047K	Pathogenic	0.736
NPC1	O15118-1.2	T1047L	Pathogenic	0.71
NPC1	O15118-1.2	T1047M	Pathogenic	0.741
NPC1	O15118-1.2	T1047N	Pathogenic	0.63
NPC1	O15118-1.2	T1047P	Pathogenic	0.741
NPC1	O15118-1.2	T1047Q	Pathogenic	0.76
NPC1	O15118-1.2	T1047R	Pathogenic	0.75
NPC1	O15118-1.2	T1047S	Pathogenic	0.608
NPC1	O15118-1.2	T1047V	Pathogenic	0.635
NPC1	O15118-1.2	T1047W	Pathogenic	0.791
NPC1	O15118-1.2	T1047Y	Pathogenic	0.836
NPC1	O15118-1.2	S1048A	Pathogenic	0.907
NPC1	O15118-1.2	S1048C	Pathogenic	0.946
NPC1	O15118-1.2	S1048D	Pathogenic	0.931
NPC1	O15118-1.2	S1048E	Pathogenic	0.94
NPC1	O15118-1.2	S1048F	Pathogenic	0.964
NPC1	O15118-1.2	S1048G	Pathogenic	0.947
NPC1	O15118-1.2	S1048H	Pathogenic	0.966
NPC1	O15118-1.2	S1048I	Pathogenic	0.961
NPC1	O15118-1.2	S1048K	Pathogenic	0.943
NPC1	O15118-1.2	S1048L	Pathogenic	0.962
NPC1	O15118-1.2	S1048M	Pathogenic	0.953
NPC1	O15118-1.2	S1048N	Pathogenic	0.909
NPC1	O15118-1.2	S1048P	Pathogenic	0.952
NPC1	O15118-1.2	S1048Q	Pathogenic	0.949
NPC1	O15118-1.2	S1048R	Pathogenic	0.963
NPC1	O15118-1.2	S1048T	Pathogenic	0.915
NPC1	O15118-1.2	S1048V	Pathogenic	0.964
NPC1	O15118-1.2	S1048W	Pathogenic	0.975
NPC1	O15118-1.2	S1048Y	Pathogenic	0.973
NPC1	O15118-1.2	A1049C	Neutral	0.292
NPC1	O15118-1.2	A1049D	Neutral	0.446
NPC1	O15118-1.2	A1049E	Neutral	0.389
NPC1	O15118-1.2	A1049F	Neutral	0.479
NPC1	O15118-1.2	A1049G	Neutral	0.318
NPC1	O15118-1.2	A1049H	Pathogenic	0.561
NPC1	O15118-1.2	A1049I	Neutral	0.368
NPC1	O15118-1.2	A1049K	Neutral	0.399
NPC1	O15118-1.2	A1049L	Neutral	0.376
NPC1	O15118-1.2	A1049M	Neutral	0.413
NPC1	O15118-1.2	A1049N	Neutral	0.468
NPC1	O15118-1.2	A1049P	Neutral	0.405
NPC1	O15118-1.2	A1049Q	Neutral	0.43
NPC1	O15118-1.2	A1049R	Neutral	0.417
NPC1	O15118-1.2	A1049S	Neutral	0.225
NPC1	O15118-1.2	A1049T	Neutral	0.346
NPC1	O15118-1.2	A1049V	Neutral	0.3
NPC1	O15118-1.2	A1049W	Pathogenic	0.579
NPC1	O15118-1.2	A1049Y	Pathogenic	0.557
NPC1	O15118-1.2	D1050A	Pathogenic	0.95
NPC1	O15118-1.2	D1050C	Pathogenic	0.952
NPC1	O15118-1.2	D1050E	Pathogenic	0.843
NPC1	O15118-1.2	D1050F	Pathogenic	0.951
NPC1	O15118-1.2	D1050G	Pathogenic	0.942
NPC1	O15118-1.2	D1050H	Pathogenic	0.933
NPC1	O15118-1.2	D1050I	Pathogenic	0.947
NPC1	O15118-1.2	D1050K	Pathogenic	0.951
NPC1	O15118-1.2	D1050L	Pathogenic	0.965
NPC1	O15118-1.2	D1050M	Pathogenic	0.956
NPC1	O15118-1.2	D1050N	Pathogenic	0.878
NPC1	O15118-1.2	D1050P	Pathogenic	0.908
NPC1	O15118-1.2	D1050Q	Pathogenic	0.913
NPC1	O15118-1.2	D1050R	Pathogenic	0.969
NPC1	O15118-1.2	D1050S	Pathogenic	0.905
NPC1	O15118-1.2	D1050T	Pathogenic	0.92
NPC1	O15118-1.2	D1050V	Pathogenic	0.951
NPC1	O15118-1.2	D1050W	Pathogenic	0.967
NPC1	O15118-1.2	D1050Y	Pathogenic	0.964
NPC1	O15118-1.2	F1051A	Pathogenic	0.895
NPC1	O15118-1.2	F1051C	Pathogenic	0.905
NPC1	O15118-1.2	F1051D	Pathogenic	0.884
NPC1	O15118-1.2	F1051E	Pathogenic	0.877
NPC1	O15118-1.2	F1051G	Pathogenic	0.927
NPC1	O15118-1.2	F1051H	Pathogenic	0.801
NPC1	O15118-1.2	F1051I	Pathogenic	0.82
NPC1	O15118-1.2	F1051K	Pathogenic	0.844
NPC1	O15118-1.2	F1051L	Pathogenic	0.817
NPC1	O15118-1.2	F1051M	Pathogenic	0.792
NPC1	O15118-1.2	F1051N	Pathogenic	0.886
NPC1	O15118-1.2	F1051P	Pathogenic	0.949
NPC1	O15118-1.2	F1051Q	Pathogenic	0.888
NPC1	O15118-1.2	F1051R	Pathogenic	0.854
NPC1	O15118-1.2	F1051S	Pathogenic	0.88
NPC1	O15118-1.2	F1051T	Pathogenic	0.878
NPC1	O15118-1.2	F1051V	Pathogenic	0.862
NPC1	O15118-1.2	F1051W	Pathogenic	0.748
NPC1	O15118-1.2	F1051Y	Pathogenic	0.515
NPC1	O15118-1.2	I1052A	Pathogenic	0.683
NPC1	O15118-1.2	I1052C	Pathogenic	0.706
NPC1	O15118-1.2	I1052D	Pathogenic	0.738
NPC1	O15118-1.2	I1052E	Pathogenic	0.725
NPC1	O15118-1.2	I1052F	Pathogenic	0.645
NPC1	O15118-1.2	I1052G	Pathogenic	0.874
NPC1	O15118-1.2	I1052H	Pathogenic	0.764
NPC1	O15118-1.2	I1052K	Pathogenic	0.696
NPC1	O15118-1.2	I1052L	Neutral	0.432
NPC1	O15118-1.2	I1052M	Neutral	0.49
NPC1	O15118-1.2	I1052N	Pathogenic	0.743
NPC1	O15118-1.2	I1052P	Pathogenic	0.823
NPC1	O15118-1.2	I1052Q	Pathogenic	0.746
NPC1	O15118-1.2	I1052R	Pathogenic	0.712
NPC1	O15118-1.2	I1052S	Pathogenic	0.732
NPC1	O15118-1.2	I1052T	Pathogenic	0.644
NPC1	O15118-1.2	I1052V	Neutral	0.331
NPC1	O15118-1.2	I1052W	Pathogenic	0.856
NPC1	O15118-1.2	I1052Y	Pathogenic	0.678
NPC1	O15118-1.2	D1053A	Neutral	0.491
NPC1	O15118-1.2	D1053C	Pathogenic	0.502
NPC1	O15118-1.2	D1053E	Neutral	0.214
NPC1	O15118-1.2	D1053F	Neutral	0.494
NPC1	O15118-1.2	D1053G	Neutral	0.449
NPC1	O15118-1.2	D1053H	Neutral	0.414
NPC1	O15118-1.2	D1053I	Neutral	0.476
NPC1	O15118-1.2	D1053K	Neutral	0.496
NPC1	O15118-1.2	D1053L	Pathogenic	0.581
NPC1	O15118-1.2	D1053M	Pathogenic	0.524
NPC1	O15118-1.2	D1053N	Neutral	0.267
NPC1	O15118-1.2	D1053P	Neutral	0.332
NPC1	O15118-1.2	D1053Q	Neutral	0.345
NPC1	O15118-1.2	D1053R	Pathogenic	0.609
NPC1	O15118-1.2	D1053S	Neutral	0.325
NPC1	O15118-1.2	D1053T	Neutral	0.368
NPC1	O15118-1.2	D1053V	Neutral	0.496
NPC1	O15118-1.2	D1053W	Pathogenic	0.594
NPC1	O15118-1.2	D1053Y	Pathogenic	0.572
NPC1	O15118-1.2	A1054C	Pathogenic	0.782
NPC1	O15118-1.2	A1054D	Pathogenic	0.875
NPC1	O15118-1.2	A1054E	Pathogenic	0.847
NPC1	O15118-1.2	A1054F	Pathogenic	0.889
NPC1	O15118-1.2	A1054G	Pathogenic	0.802
NPC1	O15118-1.2	A1054H	Pathogenic	0.917
NPC1	O15118-1.2	A1054I	Pathogenic	0.835
NPC1	O15118-1.2	A1054K	Pathogenic	0.852
NPC1	O15118-1.2	A1054L	Pathogenic	0.839
NPC1	O15118-1.2	A1054M	Pathogenic	0.859
NPC1	O15118-1.2	A1054N	Pathogenic	0.884
NPC1	O15118-1.2	A1054P	Pathogenic	0.855
NPC1	O15118-1.2	A1054Q	Pathogenic	0.868
NPC1	O15118-1.2	A1054R	Pathogenic	0.861
NPC1	O15118-1.2	A1054S	Pathogenic	0.716
NPC1	O15118-1.2	A1054T	Pathogenic	0.822
NPC1	O15118-1.2	A1054V	Pathogenic	0.788
NPC1	O15118-1.2	A1054W	Pathogenic	0.923
NPC1	O15118-1.2	A1054Y	Pathogenic	0.916
NPC1	O15118-1.2	L1055A	Pathogenic	0.765
NPC1	O15118-1.2	L1055C	Pathogenic	0.784
NPC1	O15118-1.2	L1055D	Pathogenic	0.863
NPC1	O15118-1.2	L1055E	Pathogenic	0.8
NPC1	O15118-1.2	L1055F	Pathogenic	0.722
NPC1	O15118-1.2	L1055G	Pathogenic	0.913
NPC1	O15118-1.2	L1055H	Pathogenic	0.83
NPC1	O15118-1.2	L1055I	Pathogenic	0.527
NPC1	O15118-1.2	L1055K	Pathogenic	0.702
NPC1	O15118-1.2	L1055M	Neutral	0.497
NPC1	O15118-1.2	L1055N	Pathogenic	0.814
NPC1	O15118-1.2	L1055P	Pathogenic	0.876
NPC1	O15118-1.2	L1055Q	Pathogenic	0.752
NPC1	O15118-1.2	L1055R	Pathogenic	0.718
NPC1	O15118-1.2	L1055S	Pathogenic	0.805
NPC1	O15118-1.2	L1055T	Pathogenic	0.733
NPC1	O15118-1.2	L1055V	Pathogenic	0.619
NPC1	O15118-1.2	L1055W	Pathogenic	0.851
NPC1	O15118-1.2	L1055Y	Pathogenic	0.761
NPC1	O15118-1.2	K1056A	Pathogenic	0.668
NPC1	O15118-1.2	K1056C	Pathogenic	0.756
NPC1	O15118-1.2	K1056D	Pathogenic	0.713
NPC1	O15118-1.2	K1056E	Neutral	0.497
NPC1	O15118-1.2	K1056F	Pathogenic	0.638
NPC1	O15118-1.2	K1056G	Pathogenic	0.786
NPC1	O15118-1.2	K1056H	Pathogenic	0.61
NPC1	O15118-1.2	K1056I	Pathogenic	0.652
NPC1	O15118-1.2	K1056L	Pathogenic	0.569
NPC1	O15118-1.2	K1056M	Pathogenic	0.512
NPC1	O15118-1.2	K1056N	Pathogenic	0.608
NPC1	O15118-1.2	K1056P	Pathogenic	0.604
NPC1	O15118-1.2	K1056Q	Neutral	0.455
NPC1	O15118-1.2	K1056R	Neutral	0.41
NPC1	O15118-1.2	K1056S	Pathogenic	0.597
NPC1	O15118-1.2	K1056T	Pathogenic	0.636
NPC1	O15118-1.2	K1056V	Pathogenic	0.635
NPC1	O15118-1.2	K1056W	Pathogenic	0.642
NPC1	O15118-1.2	K1056Y	Pathogenic	0.621
NPC1	O15118-1.2	K1057A	Neutral	0.466
NPC1	O15118-1.2	K1057C	Pathogenic	0.574
NPC1	O15118-1.2	K1057D	Pathogenic	0.519
NPC1	O15118-1.2	K1057E	Neutral	0.3
NPC1	O15118-1.2	K1057F	Neutral	0.434
NPC1	O15118-1.2	K1057G	Pathogenic	0.615
NPC1	O15118-1.2	K1057H	Neutral	0.405
NPC1	O15118-1.2	K1057I	Neutral	0.449
NPC1	O15118-1.2	K1057L	Neutral	0.364
NPC1	O15118-1.2	K1057M	Neutral	0.313
NPC1	O15118-1.2	K1057N	Neutral	0.403
NPC1	O15118-1.2	K1057P	Neutral	0.399
NPC1	O15118-1.2	K1057Q	Neutral	0.266
NPC1	O15118-1.2	K1057R	Neutral	0.232
NPC1	O15118-1.2	K1057S	Neutral	0.391
NPC1	O15118-1.2	K1057T	Neutral	0.432
NPC1	O15118-1.2	K1057V	Neutral	0.43
NPC1	O15118-1.2	K1057W	Neutral	0.438
NPC1	O15118-1.2	K1057Y	Neutral	0.415
NPC1	O15118-1.2	A1058C	Pathogenic	0.912
NPC1	O15118-1.2	A1058D	Pathogenic	0.953
NPC1	O15118-1.2	A1058E	Pathogenic	0.941
NPC1	O15118-1.2	A1058F	Pathogenic	0.958
NPC1	O15118-1.2	A1058G	Pathogenic	0.921
NPC1	O15118-1.2	A1058H	Pathogenic	0.97
NPC1	O15118-1.2	A1058I	Pathogenic	0.936
NPC1	O15118-1.2	A1058K	Pathogenic	0.943
NPC1	O15118-1.2	A1058L	Pathogenic	0.938
NPC1	O15118-1.2	A1058M	Pathogenic	0.946
NPC1	O15118-1.2	A1058N	Pathogenic	0.957
NPC1	O15118-1.2	A1058P	Pathogenic	0.945
NPC1	O15118-1.2	A1058Q	Pathogenic	0.95
NPC1	O15118-1.2	A1058R	Pathogenic	0.947
NPC1	O15118-1.2	A1058S	Pathogenic	0.879
NPC1	O15118-1.2	A1058T	Pathogenic	0.93
NPC1	O15118-1.2	A1058V	Pathogenic	0.915
NPC1	O15118-1.2	A1058W	Pathogenic	0.972
NPC1	O15118-1.2	A1058Y	Pathogenic	0.969
NPC1	O15118-1.2	R1059A	Pathogenic	0.934
NPC1	O15118-1.2	R1059C	Pathogenic	0.956
NPC1	O15118-1.2	R1059D	Pathogenic	0.963
NPC1	O15118-1.2	R1059E	Pathogenic	0.911
NPC1	O15118-1.2	R1059F	Pathogenic	0.926
NPC1	O15118-1.2	R1059G	Pathogenic	0.963
NPC1	O15118-1.2	R1059H	Pathogenic	0.883
NPC1	O15118-1.2	R1059I	Pathogenic	0.93
NPC1	O15118-1.2	R1059K	Pathogenic	0.82
NPC1	O15118-1.2	R1059L	Pathogenic	0.903
NPC1	O15118-1.2	R1059M	Pathogenic	0.881
NPC1	O15118-1.2	R1059N	Pathogenic	0.916
NPC1	O15118-1.2	R1059P	Pathogenic	0.941
NPC1	O15118-1.2	R1059Q	Pathogenic	0.855
NPC1	O15118-1.2	R1059S	Pathogenic	0.939
NPC1	O15118-1.2	R1059T	Pathogenic	0.925
NPC1	O15118-1.2	R1059V	Pathogenic	0.947
NPC1	O15118-1.2	R1059W	Pathogenic	0.915
NPC1	O15118-1.2	R1059Y	Pathogenic	0.915
NPC1	O15118-1.2	L1060A	Neutral	0.155
NPC1	O15118-1.2	L1060C	Neutral	0.17
NPC1	O15118-1.2	L1060D	Neutral	0.261
NPC1	O15118-1.2	L1060E	Neutral	0.183
NPC1	O15118-1.2	L1060F	Neutral	0.127
NPC1	O15118-1.2	L1060G	Neutral	0.371
NPC1	O15118-1.2	L1060H	Neutral	0.215
NPC1	O15118-1.2	L1060I	Neutral	0.059
NPC1	O15118-1.2	L1060K	Neutral	0.117
NPC1	O15118-1.2	L1060M	Neutral	0.053
NPC1	O15118-1.2	L1060N	Neutral	0.197
NPC1	O15118-1.2	L1060P	Neutral	0.283
NPC1	O15118-1.2	L1060Q	Neutral	0.145
NPC1	O15118-1.2	L1060R	Neutral	0.125
NPC1	O15118-1.2	L1060S	Neutral	0.188
NPC1	O15118-1.2	L1060T	Neutral	0.133
NPC1	O15118-1.2	L1060V	Neutral	0.083
NPC1	O15118-1.2	L1060W	Neutral	0.242
NPC1	O15118-1.2	L1060Y	Neutral	0.152
NPC1	O15118-1.2	I1061A	Pathogenic	0.775
NPC1	O15118-1.2	I1061C	Pathogenic	0.793
NPC1	O15118-1.2	I1061D	Pathogenic	0.818
NPC1	O15118-1.2	I1061E	Pathogenic	0.808
NPC1	O15118-1.2	I1061F	Pathogenic	0.743
NPC1	O15118-1.2	I1061G	Pathogenic	0.917
NPC1	O15118-1.2	I1061H	Pathogenic	0.837
NPC1	O15118-1.2	I1061K	Pathogenic	0.785
NPC1	O15118-1.2	I1061L	Pathogenic	0.549
NPC1	O15118-1.2	I1061M	Pathogenic	0.605
NPC1	O15118-1.2	I1061N	Pathogenic	0.822
NPC1	O15118-1.2	I1061P	Pathogenic	0.881
NPC1	O15118-1.2	I1061Q	Pathogenic	0.824
NPC1	O15118-1.2	I1061R	Pathogenic	0.797
NPC1	O15118-1.2	I1061S	Pathogenic	0.813
NPC1	O15118-1.2	I1061T	Pathogenic	0.743
NPC1	O15118-1.2	I1061V	Neutral	0.441
NPC1	O15118-1.2	I1061W	Pathogenic	0.904
NPC1	O15118-1.2	I1061Y	Pathogenic	0.77
NPC1	O15118-1.2	A1062C	Pathogenic	0.827
NPC1	O15118-1.2	A1062D	Pathogenic	0.903
NPC1	O15118-1.2	A1062E	Pathogenic	0.881
NPC1	O15118-1.2	A1062F	Pathogenic	0.914
NPC1	O15118-1.2	A1062G	Pathogenic	0.844
NPC1	O15118-1.2	A1062H	Pathogenic	0.937
NPC1	O15118-1.2	A1062I	Pathogenic	0.871
NPC1	O15118-1.2	A1062K	Pathogenic	0.885
NPC1	O15118-1.2	A1062L	Pathogenic	0.875
NPC1	O15118-1.2	A1062M	Pathogenic	0.891
NPC1	O15118-1.2	A1062N	Pathogenic	0.91
NPC1	O15118-1.2	A1062P	Pathogenic	0.887
NPC1	O15118-1.2	A1062Q	Pathogenic	0.897
NPC1	O15118-1.2	A1062R	Pathogenic	0.892
NPC1	O15118-1.2	A1062S	Pathogenic	0.77
NPC1	O15118-1.2	A1062T	Pathogenic	0.86
NPC1	O15118-1.2	A1062V	Pathogenic	0.832
NPC1	O15118-1.2	A1062W	Pathogenic	0.941
NPC1	O15118-1.2	A1062Y	Pathogenic	0.936
NPC1	O15118-1.2	S1063A	Neutral	0.168
NPC1	O15118-1.2	S1063C	Neutral	0.267
NPC1	O15118-1.2	S1063D	Neutral	0.219
NPC1	O15118-1.2	S1063E	Neutral	0.246
NPC1	O15118-1.2	S1063F	Neutral	0.355
NPC1	O15118-1.2	S1063G	Neutral	0.269
NPC1	O15118-1.2	S1063H	Neutral	0.369
NPC1	O15118-1.2	S1063I	Neutral	0.339
NPC1	O15118-1.2	S1063K	Neutral	0.254
NPC1	O15118-1.2	S1063L	Neutral	0.347
NPC1	O15118-1.2	S1063M	Neutral	0.296
NPC1	O15118-1.2	S1063N	Neutral	0.172
NPC1	O15118-1.2	S1063P	Neutral	0.289
NPC1	O15118-1.2	S1063Q	Neutral	0.279
NPC1	O15118-1.2	S1063R	Neutral	0.35
NPC1	O15118-1.2	S1063T	Neutral	0.183
NPC1	O15118-1.2	S1063V	Neutral	0.357
NPC1	O15118-1.2	S1063W	Neutral	0.451
NPC1	O15118-1.2	S1063Y	Neutral	0.429
NPC1	O15118-1.2	N1064A	Pathogenic	0.784
NPC1	O15118-1.2	N1064C	Pathogenic	0.792
NPC1	O15118-1.2	N1064D	Pathogenic	0.558
NPC1	O15118-1.2	N1064E	Pathogenic	0.67
NPC1	O15118-1.2	N1064F	Pathogenic	0.776
NPC1	O15118-1.2	N1064G	Pathogenic	0.676
NPC1	O15118-1.2	N1064H	Pathogenic	0.537
NPC1	O15118-1.2	N1064I	Pathogenic	0.763
NPC1	O15118-1.2	N1064K	Pathogenic	0.679
NPC1	O15118-1.2	N1064L	Pathogenic	0.77
NPC1	O15118-1.2	N1064M	Pathogenic	0.726
NPC1	O15118-1.2	N1064P	Pathogenic	0.734
NPC1	O15118-1.2	N1064Q	Pathogenic	0.652
NPC1	O15118-1.2	N1064R	Pathogenic	0.695
NPC1	O15118-1.2	N1064S	Pathogenic	0.552
NPC1	O15118-1.2	N1064T	Pathogenic	0.593
NPC1	O15118-1.2	N1064V	Pathogenic	0.778
NPC1	O15118-1.2	N1064W	Pathogenic	0.838
NPC1	O15118-1.2	N1064Y	Pathogenic	0.763
NPC1	O15118-1.2	V1065A	Pathogenic	0.705
NPC1	O15118-1.2	V1065C	Pathogenic	0.797
NPC1	O15118-1.2	V1065D	Pathogenic	0.821
NPC1	O15118-1.2	V1065E	Pathogenic	0.754
NPC1	O15118-1.2	V1065F	Pathogenic	0.789
NPC1	O15118-1.2	V1065G	Pathogenic	0.885
NPC1	O15118-1.2	V1065H	Pathogenic	0.86
NPC1	O15118-1.2	V1065I	Neutral	0.427
NPC1	O15118-1.2	V1065K	Pathogenic	0.762
NPC1	O15118-1.2	V1065L	Pathogenic	0.625
NPC1	O15118-1.2	V1065M	Pathogenic	0.661
NPC1	O15118-1.2	V1065N	Pathogenic	0.825
NPC1	O15118-1.2	V1065P	Pathogenic	0.837
NPC1	O15118-1.2	V1065Q	Pathogenic	0.784
NPC1	O15118-1.2	V1065R	Pathogenic	0.835
NPC1	O15118-1.2	V1065S	Pathogenic	0.816
NPC1	O15118-1.2	V1065T	Pathogenic	0.667
NPC1	O15118-1.2	V1065W	Pathogenic	0.892
NPC1	O15118-1.2	V1065Y	Pathogenic	0.812
NPC1	O15118-1.2	T1066A	Pathogenic	0.904
NPC1	O15118-1.2	T1066C	Pathogenic	0.908
NPC1	O15118-1.2	T1066D	Pathogenic	0.897
NPC1	O15118-1.2	T1066E	Pathogenic	0.908
NPC1	O15118-1.2	T1066F	Pathogenic	0.932
NPC1	O15118-1.2	T1066G	Pathogenic	0.955
NPC1	O15118-1.2	T1066H	Pathogenic	0.952
NPC1	O15118-1.2	T1066I	Pathogenic	0.897
NPC1	O15118-1.2	T1066K	Pathogenic	0.912
NPC1	O15118-1.2	T1066L	Pathogenic	0.9
NPC1	O15118-1.2	T1066M	Pathogenic	0.913
NPC1	O15118-1.2	T1066N	Pathogenic	0.863
NPC1	O15118-1.2	T1066P	Pathogenic	0.914
NPC1	O15118-1.2	T1066Q	Pathogenic	0.921
NPC1	O15118-1.2	T1066R	Pathogenic	0.917
NPC1	O15118-1.2	T1066S	Pathogenic	0.851
NPC1	O15118-1.2	T1066V	Pathogenic	0.865
NPC1	O15118-1.2	T1066W	Pathogenic	0.933
NPC1	O15118-1.2	T1066Y	Pathogenic	0.95
NPC1	O15118-1.2	E1067A	Neutral	0.238
NPC1	O15118-1.2	E1067C	Neutral	0.414
NPC1	O15118-1.2	E1067D	Neutral	0.1
NPC1	O15118-1.2	E1067F	Neutral	0.272
NPC1	O15118-1.2	E1067G	Neutral	0.363
NPC1	O15118-1.2	E1067H	Neutral	0.155
NPC1	O15118-1.2	E1067I	Neutral	0.258
NPC1	O15118-1.2	E1067K	Neutral	0.137
NPC1	O15118-1.2	E1067L	Neutral	0.265
NPC1	O15118-1.2	E1067M	Neutral	0.223
NPC1	O15118-1.2	E1067N	Neutral	0.194
NPC1	O15118-1.2	E1067P	Neutral	0.191
NPC1	O15118-1.2	E1067Q	Neutral	0.085
NPC1	O15118-1.2	E1067R	Neutral	0.201
NPC1	O15118-1.2	E1067S	Neutral	0.186
NPC1	O15118-1.2	E1067T	Neutral	0.213
NPC1	O15118-1.2	E1067V	Neutral	0.212
NPC1	O15118-1.2	E1067W	Neutral	0.275
NPC1	O15118-1.2	E1067Y	Neutral	0.258
NPC1	O15118-1.2	T1068A	Neutral	0.483
NPC1	O15118-1.2	T1068C	Neutral	0.494
NPC1	O15118-1.2	T1068D	Neutral	0.462
NPC1	O15118-1.2	T1068E	Neutral	0.494
NPC1	O15118-1.2	T1068F	Pathogenic	0.576
NPC1	O15118-1.2	T1068G	Pathogenic	0.679
NPC1	O15118-1.2	T1068H	Pathogenic	0.662
NPC1	O15118-1.2	T1068I	Neutral	0.462
NPC1	O15118-1.2	T1068K	Pathogenic	0.504
NPC1	O15118-1.2	T1068L	Neutral	0.471
NPC1	O15118-1.2	T1068M	Pathogenic	0.51
NPC1	O15118-1.2	T1068N	Neutral	0.383
NPC1	O15118-1.2	T1068P	Pathogenic	0.51
NPC1	O15118-1.2	T1068Q	Pathogenic	0.536
NPC1	O15118-1.2	T1068R	Pathogenic	0.522
NPC1	O15118-1.2	T1068S	Neutral	0.361
NPC1	O15118-1.2	T1068V	Neutral	0.388
NPC1	O15118-1.2	T1068W	Pathogenic	0.58
NPC1	O15118-1.2	T1068Y	Pathogenic	0.65
NPC1	O15118-1.2	M1069A	Pathogenic	0.749
NPC1	O15118-1.2	M1069C	Pathogenic	0.769
NPC1	O15118-1.2	M1069D	Pathogenic	0.796
NPC1	O15118-1.2	M1069E	Pathogenic	0.713
NPC1	O15118-1.2	M1069F	Pathogenic	0.634
NPC1	O15118-1.2	M1069G	Pathogenic	0.867
NPC1	O15118-1.2	M1069H	Pathogenic	0.752
NPC1	O15118-1.2	M1069I	Pathogenic	0.523
NPC1	O15118-1.2	M1069K	Pathogenic	0.595
NPC1	O15118-1.2	M1069L	Neutral	0.436
NPC1	O15118-1.2	M1069N	Pathogenic	0.731
NPC1	O15118-1.2	M1069P	Pathogenic	0.814
NPC1	O15118-1.2	M1069Q	Pathogenic	0.562
NPC1	O15118-1.2	M1069R	Pathogenic	0.612
NPC1	O15118-1.2	M1069S	Pathogenic	0.72
NPC1	O15118-1.2	M1069T	Pathogenic	0.715
NPC1	O15118-1.2	M1069V	Pathogenic	0.597
NPC1	O15118-1.2	M1069W	Pathogenic	0.722
NPC1	O15118-1.2	M1069Y	Pathogenic	0.744
NPC1	O15118-1.2	G1070A	Neutral	0.344
NPC1	O15118-1.2	G1070C	Pathogenic	0.599
NPC1	O15118-1.2	G1070D	Neutral	0.433
NPC1	O15118-1.2	G1070E	Pathogenic	0.567
NPC1	O15118-1.2	G1070F	Pathogenic	0.606
NPC1	O15118-1.2	G1070H	Pathogenic	0.62
NPC1	O15118-1.2	G1070I	Pathogenic	0.678
NPC1	O15118-1.2	G1070K	Pathogenic	0.577
NPC1	O15118-1.2	G1070L	Pathogenic	0.685
NPC1	O15118-1.2	G1070M	Pathogenic	0.634
NPC1	O15118-1.2	G1070N	Neutral	0.361
NPC1	O15118-1.2	G1070P	Pathogenic	0.532
NPC1	O15118-1.2	G1070Q	Pathogenic	0.608
NPC1	O15118-1.2	G1070R	Pathogenic	0.595
NPC1	O15118-1.2	G1070S	Neutral	0.373
NPC1	O15118-1.2	G1070T	Pathogenic	0.574
NPC1	O15118-1.2	G1070V	Pathogenic	0.608
NPC1	O15118-1.2	G1070W	Pathogenic	0.515
NPC1	O15118-1.2	G1070Y	Pathogenic	0.677
NPC1	O15118-1.2	I1071A	Neutral	0.199
NPC1	O15118-1.2	I1071C	Neutral	0.217
NPC1	O15118-1.2	I1071D	Neutral	0.246
NPC1	O15118-1.2	I1071E	Neutral	0.234
NPC1	O15118-1.2	I1071F	Neutral	0.173
NPC1	O15118-1.2	I1071G	Neutral	0.445
NPC1	O15118-1.2	I1071H	Neutral	0.272
NPC1	O15118-1.2	I1071K	Neutral	0.209
NPC1	O15118-1.2	I1071L	Neutral	0.081
NPC1	O15118-1.2	I1071M	Neutral	0.1
NPC1	O15118-1.2	I1071N	Neutral	0.25
NPC1	O15118-1.2	I1071P	Neutral	0.349
NPC1	O15118-1.2	I1071Q	Neutral	0.254
NPC1	O15118-1.2	I1071R	Neutral	0.222
NPC1	O15118-1.2	I1071S	Neutral	0.24
NPC1	O15118-1.2	I1071T	Neutral	0.173
NPC1	O15118-1.2	I1071V	Neutral	0.054
NPC1	O15118-1.2	I1071W	Neutral	0.406
NPC1	O15118-1.2	I1071Y	Neutral	0.195
NPC1	O15118-1.2	N1072A	Neutral	0.045
NPC1	O15118-1.2	N1072C	Neutral	0.048
NPC1	O15118-1.2	N1072D	Neutral	0.016
NPC1	O15118-1.2	N1072E	Neutral	0.026
NPC1	O15118-1.2	N1072F	Neutral	0.044
NPC1	O15118-1.2	N1072G	Neutral	0.027
NPC1	O15118-1.2	N1072H	Neutral	0.015
NPC1	O15118-1.2	N1072I	Neutral	0.041
NPC1	O15118-1.2	N1072K	Neutral	0.027
NPC1	O15118-1.2	N1072L	Neutral	0.042
NPC1	O15118-1.2	N1072M	Neutral	0.034
NPC1	O15118-1.2	N1072P	Neutral	0.035
NPC1	O15118-1.2	N1072Q	Neutral	0.024
NPC1	O15118-1.2	N1072R	Neutral	0.029
NPC1	O15118-1.2	N1072S	Neutral	0.016
NPC1	O15118-1.2	N1072T	Neutral	0.019
NPC1	O15118-1.2	N1072V	Neutral	0.044
NPC1	O15118-1.2	N1072W	Neutral	0.064
NPC1	O15118-1.2	N1072Y	Neutral	0.041
NPC1	O15118-1.2	G1073A	Neutral	0.27
NPC1	O15118-1.2	G1073C	Pathogenic	0.513
NPC1	O15118-1.2	G1073D	Neutral	0.35
NPC1	O15118-1.2	G1073E	Neutral	0.48
NPC1	O15118-1.2	G1073F	Pathogenic	0.52
NPC1	O15118-1.2	G1073H	Pathogenic	0.536
NPC1	O15118-1.2	G1073I	Pathogenic	0.598
NPC1	O15118-1.2	G1073K	Neutral	0.49
NPC1	O15118-1.2	G1073L	Pathogenic	0.606
NPC1	O15118-1.2	G1073M	Pathogenic	0.55
NPC1	O15118-1.2	G1073N	Neutral	0.285
NPC1	O15118-1.2	G1073P	Neutral	0.445
NPC1	O15118-1.2	G1073Q	Pathogenic	0.522
NPC1	O15118-1.2	G1073R	Pathogenic	0.509
NPC1	O15118-1.2	G1073S	Neutral	0.295
NPC1	O15118-1.2	G1073T	Neutral	0.488
NPC1	O15118-1.2	G1073V	Pathogenic	0.522
NPC1	O15118-1.2	G1073W	Neutral	0.428
NPC1	O15118-1.2	G1073Y	Pathogenic	0.597
NPC1	O15118-1.2	S1074A	Neutral	0.118
NPC1	O15118-1.2	S1074C	Neutral	0.195
NPC1	O15118-1.2	S1074D	Neutral	0.157
NPC1	O15118-1.2	S1074E	Neutral	0.178
NPC1	O15118-1.2	S1074F	Neutral	0.268
NPC1	O15118-1.2	S1074G	Neutral	0.197
NPC1	O15118-1.2	S1074H	Neutral	0.28
NPC1	O15118-1.2	S1074I	Neutral	0.254
NPC1	O15118-1.2	S1074K	Neutral	0.184
NPC1	O15118-1.2	S1074L	Neutral	0.26
NPC1	O15118-1.2	S1074M	Neutral	0.219
NPC1	O15118-1.2	S1074N	Neutral	0.121
NPC1	O15118-1.2	S1074P	Neutral	0.213
NPC1	O15118-1.2	S1074Q	Neutral	0.204
NPC1	O15118-1.2	S1074R	Neutral	0.263
NPC1	O15118-1.2	S1074T	Neutral	0.129
NPC1	O15118-1.2	S1074V	Neutral	0.269
NPC1	O15118-1.2	S1074W	Neutral	0.353
NPC1	O15118-1.2	S1074Y	Neutral	0.333
NPC1	O15118-1.2	A1075C	Neutral	0.072
NPC1	O15118-1.2	A1075D	Neutral	0.132
NPC1	O15118-1.2	A1075E	Neutral	0.108
NPC1	O15118-1.2	A1075F	Neutral	0.148
NPC1	O15118-1.2	A1075G	Neutral	0.081
NPC1	O15118-1.2	A1075H	Neutral	0.195
NPC1	O15118-1.2	A1075I	Neutral	0.099
NPC1	O15118-1.2	A1075K	Neutral	0.112
NPC1	O15118-1.2	A1075L	Neutral	0.102
NPC1	O15118-1.2	A1075M	Neutral	0.117
NPC1	O15118-1.2	A1075N	Neutral	0.142
NPC1	O15118-1.2	A1075P	Neutral	0.114
NPC1	O15118-1.2	A1075Q	Neutral	0.125
NPC1	O15118-1.2	A1075R	Neutral	0.119
NPC1	O15118-1.2	A1075S	Neutral	0.052
NPC1	O15118-1.2	A1075T	Neutral	0.091
NPC1	O15118-1.2	A1075V	Neutral	0.075
NPC1	O15118-1.2	A1075W	Neutral	0.206
NPC1	O15118-1.2	A1075Y	Neutral	0.192
NPC1	O15118-1.2	Y1076A	Pathogenic	0.559
NPC1	O15118-1.2	Y1076C	Pathogenic	0.582
NPC1	O15118-1.2	Y1076D	Pathogenic	0.53
NPC1	O15118-1.2	Y1076E	Neutral	0.418
NPC1	O15118-1.2	Y1076F	Neutral	0.103
NPC1	O15118-1.2	Y1076G	Pathogenic	0.654
NPC1	O15118-1.2	Y1076H	Neutral	0.158
NPC1	O15118-1.2	Y1076I	Neutral	0.365
NPC1	O15118-1.2	Y1076K	Neutral	0.353
NPC1	O15118-1.2	Y1076L	Neutral	0.372
NPC1	O15118-1.2	Y1076M	Neutral	0.41
NPC1	O15118-1.2	Y1076N	Neutral	0.44
NPC1	O15118-1.2	Y1076P	Pathogenic	0.651
NPC1	O15118-1.2	Y1076Q	Neutral	0.353
NPC1	O15118-1.2	Y1076R	Neutral	0.354
NPC1	O15118-1.2	Y1076S	Pathogenic	0.522
NPC1	O15118-1.2	Y1076T	Pathogenic	0.516
NPC1	O15118-1.2	Y1076V	Neutral	0.439
NPC1	O15118-1.2	Y1076W	Neutral	0.138
NPC1	O15118-1.2	R1077A	Pathogenic	0.645
NPC1	O15118-1.2	R1077C	Pathogenic	0.737
NPC1	O15118-1.2	R1077D	Pathogenic	0.768
NPC1	O15118-1.2	R1077E	Pathogenic	0.567
NPC1	O15118-1.2	R1077F	Pathogenic	0.614
NPC1	O15118-1.2	R1077G	Pathogenic	0.768
NPC1	O15118-1.2	R1077H	Neutral	0.49
NPC1	O15118-1.2	R1077I	Pathogenic	0.629
NPC1	O15118-1.2	R1077K	Neutral	0.368
NPC1	O15118-1.2	R1077L	Pathogenic	0.544
NPC1	O15118-1.2	R1077M	Neutral	0.486
NPC1	O15118-1.2	R1077N	Pathogenic	0.584
NPC1	O15118-1.2	R1077P	Pathogenic	0.67
NPC1	O15118-1.2	R1077Q	Neutral	0.429
NPC1	O15118-1.2	R1077S	Pathogenic	0.663
NPC1	O15118-1.2	R1077T	Pathogenic	0.612
NPC1	O15118-1.2	R1077V	Pathogenic	0.698
NPC1	O15118-1.2	R1077W	Pathogenic	0.58
NPC1	O15118-1.2	R1077Y	Pathogenic	0.579
NPC1	O15118-1.2	V1078A	Pathogenic	0.925
NPC1	O15118-1.2	V1078C	Pathogenic	0.953
NPC1	O15118-1.2	V1078D	Pathogenic	0.959
NPC1	O15118-1.2	V1078E	Pathogenic	0.941
NPC1	O15118-1.2	V1078F	Pathogenic	0.951
NPC1	O15118-1.2	V1078G	Pathogenic	0.975
NPC1	O15118-1.2	V1078H	Pathogenic	0.969
NPC1	O15118-1.2	V1078I	Pathogenic	0.793
NPC1	O15118-1.2	V1078K	Pathogenic	0.943
NPC1	O15118-1.2	V1078L	Pathogenic	0.896
NPC1	O15118-1.2	V1078M	Pathogenic	0.909
NPC1	O15118-1.2	V1078N	Pathogenic	0.96
NPC1	O15118-1.2	V1078P	Pathogenic	0.964
NPC1	O15118-1.2	V1078Q	Pathogenic	0.949
NPC1	O15118-1.2	V1078R	Pathogenic	0.963
NPC1	O15118-1.2	V1078S	Pathogenic	0.958
NPC1	O15118-1.2	V1078T	Pathogenic	0.912
NPC1	O15118-1.2	V1078W	Pathogenic	0.977
NPC1	O15118-1.2	V1078Y	Pathogenic	0.957
NPC1	O15118-1.2	F1079A	Pathogenic	0.97
NPC1	O15118-1.2	F1079C	Pathogenic	0.973
NPC1	O15118-1.2	F1079D	Pathogenic	0.967
NPC1	O15118-1.2	F1079E	Pathogenic	0.965
NPC1	O15118-1.2	F1079G	Pathogenic	0.98
NPC1	O15118-1.2	F1079H	Pathogenic	0.939
NPC1	O15118-1.2	F1079I	Pathogenic	0.946
NPC1	O15118-1.2	F1079K	Pathogenic	0.954
NPC1	O15118-1.2	F1079L	Pathogenic	0.944
NPC1	O15118-1.2	F1079M	Pathogenic	0.936
NPC1	O15118-1.2	F1079N	Pathogenic	0.967
NPC1	O15118-1.2	F1079P	Pathogenic	0.986
NPC1	O15118-1.2	F1079Q	Pathogenic	0.968
NPC1	O15118-1.2	F1079R	Pathogenic	0.957
NPC1	O15118-1.2	F1079S	Pathogenic	0.966
NPC1	O15118-1.2	F1079T	Pathogenic	0.965
NPC1	O15118-1.2	F1079V	Pathogenic	0.96
NPC1	O15118-1.2	F1079W	Pathogenic	0.919
NPC1	O15118-1.2	F1079Y	Pathogenic	0.802
NPC1	O15118-1.2	P1080A	Pathogenic	0.945
NPC1	O15118-1.2	P1080C	Pathogenic	0.972
NPC1	O15118-1.2	P1080D	Pathogenic	0.914
NPC1	O15118-1.2	P1080E	Pathogenic	0.925
NPC1	O15118-1.2	P1080F	Pathogenic	0.981
NPC1	O15118-1.2	P1080G	Pathogenic	0.963
NPC1	O15118-1.2	P1080H	Pathogenic	0.961
NPC1	O15118-1.2	P1080I	Pathogenic	0.97
NPC1	O15118-1.2	P1080K	Pathogenic	0.928
NPC1	O15118-1.2	P1080L	Pathogenic	0.971
NPC1	O15118-1.2	P1080M	Pathogenic	0.963
NPC1	O15118-1.2	P1080N	Pathogenic	0.944
NPC1	O15118-1.2	P1080Q	Pathogenic	0.936
NPC1	O15118-1.2	P1080R	Pathogenic	0.953
NPC1	O15118-1.2	P1080S	Pathogenic	0.937
NPC1	O15118-1.2	P1080T	Pathogenic	0.938
NPC1	O15118-1.2	P1080V	Pathogenic	0.959
NPC1	O15118-1.2	P1080W	Pathogenic	0.981
NPC1	O15118-1.2	P1080Y	Pathogenic	0.979
NPC1	O15118-1.2	Y1081A	Pathogenic	0.982
NPC1	O15118-1.2	Y1081C	Pathogenic	0.983
NPC1	O15118-1.2	Y1081D	Pathogenic	0.979
NPC1	O15118-1.2	Y1081E	Pathogenic	0.968
NPC1	O15118-1.2	Y1081F	Pathogenic	0.829
NPC1	O15118-1.2	Y1081G	Pathogenic	0.988
NPC1	O15118-1.2	Y1081H	Pathogenic	0.888
NPC1	O15118-1.2	Y1081I	Pathogenic	0.96
NPC1	O15118-1.2	Y1081K	Pathogenic	0.958
NPC1	O15118-1.2	Y1081L	Pathogenic	0.962
NPC1	O15118-1.2	Y1081M	Pathogenic	0.967
NPC1	O15118-1.2	Y1081N	Pathogenic	0.971
NPC1	O15118-1.2	Y1081P	Pathogenic	0.987
NPC1	O15118-1.2	Y1081Q	Pathogenic	0.958
NPC1	O15118-1.2	Y1081R	Pathogenic	0.958
NPC1	O15118-1.2	Y1081S	Pathogenic	0.979
NPC1	O15118-1.2	Y1081T	Pathogenic	0.978
NPC1	O15118-1.2	Y1081V	Pathogenic	0.971
NPC1	O15118-1.2	Y1081W	Pathogenic	0.871
NPC1	O15118-1.2	S1082A	Pathogenic	0.849
NPC1	O15118-1.2	S1082C	Pathogenic	0.91
NPC1	O15118-1.2	S1082D	Pathogenic	0.887
NPC1	O15118-1.2	S1082E	Pathogenic	0.901
NPC1	O15118-1.2	S1082F	Pathogenic	0.939
NPC1	O15118-1.2	S1082G	Pathogenic	0.911
NPC1	O15118-1.2	S1082H	Pathogenic	0.942
NPC1	O15118-1.2	S1082I	Pathogenic	0.935
NPC1	O15118-1.2	S1082K	Pathogenic	0.905
NPC1	O15118-1.2	S1082L	Pathogenic	0.937
NPC1	O15118-1.2	S1082M	Pathogenic	0.922
NPC1	O15118-1.2	S1082N	Pathogenic	0.853
NPC1	O15118-1.2	S1082P	Pathogenic	0.919
NPC1	O15118-1.2	S1082Q	Pathogenic	0.915
NPC1	O15118-1.2	S1082R	Pathogenic	0.938
NPC1	O15118-1.2	S1082T	Pathogenic	0.862
NPC1	O15118-1.2	S1082V	Pathogenic	0.939
NPC1	O15118-1.2	S1082W	Pathogenic	0.958
NPC1	O15118-1.2	S1082Y	Pathogenic	0.954
NPC1	O15118-1.2	V1083A	Pathogenic	0.766
NPC1	O15118-1.2	V1083C	Pathogenic	0.843
NPC1	O15118-1.2	V1083D	Pathogenic	0.863
NPC1	O15118-1.2	V1083E	Pathogenic	0.808
NPC1	O15118-1.2	V1083F	Pathogenic	0.837
NPC1	O15118-1.2	V1083G	Pathogenic	0.913
NPC1	O15118-1.2	V1083H	Pathogenic	0.894
NPC1	O15118-1.2	V1083I	Pathogenic	0.505
NPC1	O15118-1.2	V1083K	Pathogenic	0.814
NPC1	O15118-1.2	V1083L	Pathogenic	0.695
NPC1	O15118-1.2	V1083M	Pathogenic	0.727
NPC1	O15118-1.2	V1083N	Pathogenic	0.866
NPC1	O15118-1.2	V1083P	Pathogenic	0.876
NPC1	O15118-1.2	V1083Q	Pathogenic	0.833
NPC1	O15118-1.2	V1083R	Pathogenic	0.874
NPC1	O15118-1.2	V1083S	Pathogenic	0.859
NPC1	O15118-1.2	V1083T	Pathogenic	0.733
NPC1	O15118-1.2	V1083W	Pathogenic	0.919
NPC1	O15118-1.2	V1083Y	Pathogenic	0.855
NPC1	O15118-1.2	F1084A	Pathogenic	0.943
NPC1	O15118-1.2	F1084C	Pathogenic	0.948
NPC1	O15118-1.2	F1084D	Pathogenic	0.936
NPC1	O15118-1.2	F1084E	Pathogenic	0.932
NPC1	O15118-1.2	F1084G	Pathogenic	0.961
NPC1	O15118-1.2	F1084H	Pathogenic	0.886
NPC1	O15118-1.2	F1084I	Pathogenic	0.898
NPC1	O15118-1.2	F1084K	Pathogenic	0.913
NPC1	O15118-1.2	F1084L	Pathogenic	0.896
NPC1	O15118-1.2	F1084M	Pathogenic	0.88
NPC1	O15118-1.2	F1084N	Pathogenic	0.938
NPC1	O15118-1.2	F1084P	Pathogenic	0.973
NPC1	O15118-1.2	F1084Q	Pathogenic	0.939
NPC1	O15118-1.2	F1084R	Pathogenic	0.918
NPC1	O15118-1.2	F1084S	Pathogenic	0.934
NPC1	O15118-1.2	F1084T	Pathogenic	0.933
NPC1	O15118-1.2	F1084V	Pathogenic	0.923
NPC1	O15118-1.2	F1084W	Pathogenic	0.851
NPC1	O15118-1.2	F1084Y	Pathogenic	0.672
NPC1	O15118-1.2	Y1085A	Pathogenic	0.976
NPC1	O15118-1.2	Y1085C	Pathogenic	0.979
NPC1	O15118-1.2	Y1085D	Pathogenic	0.974
NPC1	O15118-1.2	Y1085E	Pathogenic	0.959
NPC1	O15118-1.2	Y1085F	Pathogenic	0.79
NPC1	O15118-1.2	Y1085G	Pathogenic	0.984
NPC1	O15118-1.2	Y1085H	Pathogenic	0.86
NPC1	O15118-1.2	Y1085I	Pathogenic	0.949
NPC1	O15118-1.2	Y1085K	Pathogenic	0.947
NPC1	O15118-1.2	Y1085L	Pathogenic	0.951
NPC1	O15118-1.2	Y1085M	Pathogenic	0.958
NPC1	O15118-1.2	Y1085N	Pathogenic	0.963
NPC1	O15118-1.2	Y1085P	Pathogenic	0.984
NPC1	O15118-1.2	Y1085Q	Pathogenic	0.947
NPC1	O15118-1.2	Y1085R	Pathogenic	0.947
NPC1	O15118-1.2	Y1085S	Pathogenic	0.973
NPC1	O15118-1.2	Y1085T	Pathogenic	0.972
NPC1	O15118-1.2	Y1085V	Pathogenic	0.962
NPC1	O15118-1.2	Y1085W	Pathogenic	0.84
NPC1	O15118-1.2	V1086A	Pathogenic	0.92
NPC1	O15118-1.2	V1086C	Pathogenic	0.95
NPC1	O15118-1.2	V1086D	Pathogenic	0.957
NPC1	O15118-1.2	V1086E	Pathogenic	0.937
NPC1	O15118-1.2	V1086F	Pathogenic	0.948
NPC1	O15118-1.2	V1086G	Pathogenic	0.974
NPC1	O15118-1.2	V1086H	Pathogenic	0.967
NPC1	O15118-1.2	V1086I	Pathogenic	0.782
NPC1	O15118-1.2	V1086K	Pathogenic	0.939
NPC1	O15118-1.2	V1086L	Pathogenic	0.889
NPC1	O15118-1.2	V1086M	Pathogenic	0.904
NPC1	O15118-1.2	V1086N	Pathogenic	0.958
NPC1	O15118-1.2	V1086P	Pathogenic	0.961
NPC1	O15118-1.2	V1086Q	Pathogenic	0.946
NPC1	O15118-1.2	V1086R	Pathogenic	0.961
NPC1	O15118-1.2	V1086S	Pathogenic	0.955
NPC1	O15118-1.2	V1086T	Pathogenic	0.906
NPC1	O15118-1.2	V1086W	Pathogenic	0.975
NPC1	O15118-1.2	V1086Y	Pathogenic	0.954
NPC1	O15118-1.2	F1087A	Pathogenic	0.955
NPC1	O15118-1.2	F1087C	Pathogenic	0.96
NPC1	O15118-1.2	F1087D	Pathogenic	0.95
NPC1	O15118-1.2	F1087E	Pathogenic	0.947
NPC1	O15118-1.2	F1087G	Pathogenic	0.969
NPC1	O15118-1.2	F1087H	Pathogenic	0.909
NPC1	O15118-1.2	F1087I	Pathogenic	0.919
NPC1	O15118-1.2	F1087K	Pathogenic	0.931
NPC1	O15118-1.2	F1087L	Pathogenic	0.917
NPC1	O15118-1.2	F1087M	Pathogenic	0.905
NPC1	O15118-1.2	F1087N	Pathogenic	0.951
NPC1	O15118-1.2	F1087P	Pathogenic	0.979
NPC1	O15118-1.2	F1087Q	Pathogenic	0.952
NPC1	O15118-1.2	F1087R	Pathogenic	0.936
NPC1	O15118-1.2	F1087S	Pathogenic	0.948
NPC1	O15118-1.2	F1087T	Pathogenic	0.947
NPC1	O15118-1.2	F1087V	Pathogenic	0.94
NPC1	O15118-1.2	F1087W	Pathogenic	0.881
NPC1	O15118-1.2	F1087Y	Pathogenic	0.725
NPC1	O15118-1.2	Y1088A	Pathogenic	0.981
NPC1	O15118-1.2	Y1088C	Pathogenic	0.982
NPC1	O15118-1.2	Y1088D	Pathogenic	0.978
NPC1	O15118-1.2	Y1088E	Pathogenic	0.966
NPC1	O15118-1.2	Y1088F	Pathogenic	0.821
NPC1	O15118-1.2	Y1088G	Pathogenic	0.987
NPC1	O15118-1.2	Y1088H	Pathogenic	0.882
NPC1	O15118-1.2	Y1088I	Pathogenic	0.958
NPC1	O15118-1.2	Y1088K	Pathogenic	0.956
NPC1	O15118-1.2	Y1088L	Pathogenic	0.959
NPC1	O15118-1.2	Y1088M	Pathogenic	0.965
NPC1	O15118-1.2	Y1088N	Pathogenic	0.969
NPC1	O15118-1.2	Y1088P	Pathogenic	0.987
NPC1	O15118-1.2	Y1088Q	Pathogenic	0.956
NPC1	O15118-1.2	Y1088R	Pathogenic	0.956
NPC1	O15118-1.2	Y1088S	Pathogenic	0.978
NPC1	O15118-1.2	Y1088T	Pathogenic	0.977
NPC1	O15118-1.2	Y1088V	Pathogenic	0.969
NPC1	O15118-1.2	Y1088W	Pathogenic	0.865
NPC1	O15118-1.2	E1089A	Pathogenic	0.963
NPC1	O15118-1.2	E1089C	Pathogenic	0.983
NPC1	O15118-1.2	E1089D	Pathogenic	0.903
NPC1	O15118-1.2	E1089F	Pathogenic	0.969
NPC1	O15118-1.2	E1089G	Pathogenic	0.979
NPC1	O15118-1.2	E1089H	Pathogenic	0.939
NPC1	O15118-1.2	E1089I	Pathogenic	0.967
NPC1	O15118-1.2	E1089K	Pathogenic	0.93
NPC1	O15118-1.2	E1089L	Pathogenic	0.968
NPC1	O15118-1.2	E1089M	Pathogenic	0.96
NPC1	O15118-1.2	E1089N	Pathogenic	0.953
NPC1	O15118-1.2	E1089P	Pathogenic	0.952
NPC1	O15118-1.2	E1089Q	Pathogenic	0.886
NPC1	O15118-1.2	E1089R	Pathogenic	0.955
NPC1	O15118-1.2	E1089S	Pathogenic	0.95
NPC1	O15118-1.2	E1089T	Pathogenic	0.958
NPC1	O15118-1.2	E1089V	Pathogenic	0.957
NPC1	O15118-1.2	E1089W	Pathogenic	0.969
NPC1	O15118-1.2	E1089Y	Pathogenic	0.967
NPC1	O15118-1.2	Q1090A	Pathogenic	0.971
NPC1	O15118-1.2	Q1090C	Pathogenic	0.981
NPC1	O15118-1.2	Q1090D	Pathogenic	0.951
NPC1	O15118-1.2	Q1090E	Pathogenic	0.893
NPC1	O15118-1.2	Q1090F	Pathogenic	0.974
NPC1	O15118-1.2	Q1090G	Pathogenic	0.984
NPC1	O15118-1.2	Q1090H	Pathogenic	0.948
NPC1	O15118-1.2	Q1090I	Pathogenic	0.972
NPC1	O15118-1.2	Q1090K	Pathogenic	0.923
NPC1	O15118-1.2	Q1090L	Pathogenic	0.961
NPC1	O15118-1.2	Q1090M	Pathogenic	0.93
NPC1	O15118-1.2	Q1090N	Pathogenic	0.952
NPC1	O15118-1.2	Q1090P	Pathogenic	0.962
NPC1	O15118-1.2	Q1090R	Pathogenic	0.928
NPC1	O15118-1.2	Q1090S	Pathogenic	0.96
NPC1	O15118-1.2	Q1090T	Pathogenic	0.966
NPC1	O15118-1.2	Q1090V	Pathogenic	0.966
NPC1	O15118-1.2	Q1090W	Pathogenic	0.963
NPC1	O15118-1.2	Q1090Y	Pathogenic	0.959
NPC1	O15118-1.2	Y1091A	Pathogenic	0.981
NPC1	O15118-1.2	Y1091C	Pathogenic	0.982
NPC1	O15118-1.2	Y1091D	Pathogenic	0.978
NPC1	O15118-1.2	Y1091E	Pathogenic	0.966
NPC1	O15118-1.2	Y1091F	Pathogenic	0.821
NPC1	O15118-1.2	Y1091G	Pathogenic	0.987
NPC1	O15118-1.2	Y1091H	Pathogenic	0.882
NPC1	O15118-1.2	Y1091I	Pathogenic	0.958
NPC1	O15118-1.2	Y1091K	Pathogenic	0.956
NPC1	O15118-1.2	Y1091L	Pathogenic	0.959
NPC1	O15118-1.2	Y1091M	Pathogenic	0.965
NPC1	O15118-1.2	Y1091N	Pathogenic	0.969
NPC1	O15118-1.2	Y1091P	Pathogenic	0.987
NPC1	O15118-1.2	Y1091Q	Pathogenic	0.956
NPC1	O15118-1.2	Y1091R	Pathogenic	0.956
NPC1	O15118-1.2	Y1091S	Pathogenic	0.978
NPC1	O15118-1.2	Y1091T	Pathogenic	0.977
NPC1	O15118-1.2	Y1091V	Pathogenic	0.969
NPC1	O15118-1.2	Y1091W	Pathogenic	0.865
NPC1	O15118-1.2	L1092A	Pathogenic	0.929
NPC1	O15118-1.2	L1092C	Pathogenic	0.936
NPC1	O15118-1.2	L1092D	Pathogenic	0.962
NPC1	O15118-1.2	L1092E	Pathogenic	0.942
NPC1	O15118-1.2	L1092F	Pathogenic	0.913
NPC1	O15118-1.2	L1092G	Pathogenic	0.977
NPC1	O15118-1.2	L1092H	Pathogenic	0.952
NPC1	O15118-1.2	L1092I	Pathogenic	0.818
NPC1	O15118-1.2	L1092K	Pathogenic	0.905
NPC1	O15118-1.2	L1092M	Pathogenic	0.799
NPC1	O15118-1.2	L1092N	Pathogenic	0.946
NPC1	O15118-1.2	L1092P	Pathogenic	0.966
NPC1	O15118-1.2	L1092Q	Pathogenic	0.924
NPC1	O15118-1.2	L1092R	Pathogenic	0.911
NPC1	O15118-1.2	L1092S	Pathogenic	0.943
NPC1	O15118-1.2	L1092T	Pathogenic	0.917
NPC1	O15118-1.2	L1092V	Pathogenic	0.867
NPC1	O15118-1.2	L1092W	Pathogenic	0.958
NPC1	O15118-1.2	L1092Y	Pathogenic	0.928
NPC1	O15118-1.2	T1093A	Pathogenic	0.932
NPC1	O15118-1.2	T1093C	Pathogenic	0.935
NPC1	O15118-1.2	T1093D	Pathogenic	0.926
NPC1	O15118-1.2	T1093E	Pathogenic	0.935
NPC1	O15118-1.2	T1093F	Pathogenic	0.952
NPC1	O15118-1.2	T1093G	Pathogenic	0.969
NPC1	O15118-1.2	T1093H	Pathogenic	0.966
NPC1	O15118-1.2	T1093I	Pathogenic	0.927
NPC1	O15118-1.2	T1093K	Pathogenic	0.937
NPC1	O15118-1.2	T1093L	Pathogenic	0.929
NPC1	O15118-1.2	T1093M	Pathogenic	0.939
NPC1	O15118-1.2	T1093N	Pathogenic	0.901
NPC1	O15118-1.2	T1093P	Pathogenic	0.939
NPC1	O15118-1.2	T1093Q	Pathogenic	0.944
NPC1	O15118-1.2	T1093R	Pathogenic	0.941
NPC1	O15118-1.2	T1093S	Pathogenic	0.892
NPC1	O15118-1.2	T1093V	Pathogenic	0.903
NPC1	O15118-1.2	T1093W	Pathogenic	0.953
NPC1	O15118-1.2	T1093Y	Pathogenic	0.965
NPC1	O15118-1.2	I1094A	Pathogenic	0.751
NPC1	O15118-1.2	I1094C	Pathogenic	0.771
NPC1	O15118-1.2	I1094D	Pathogenic	0.798
NPC1	O15118-1.2	I1094E	Pathogenic	0.787
NPC1	O15118-1.2	I1094F	Pathogenic	0.717
NPC1	O15118-1.2	I1094G	Pathogenic	0.907
NPC1	O15118-1.2	I1094H	Pathogenic	0.819
NPC1	O15118-1.2	I1094K	Pathogenic	0.762
NPC1	O15118-1.2	I1094L	Pathogenic	0.516
NPC1	O15118-1.2	I1094M	Pathogenic	0.573
NPC1	O15118-1.2	I1094N	Pathogenic	0.802
NPC1	O15118-1.2	I1094P	Pathogenic	0.867
NPC1	O15118-1.2	I1094Q	Pathogenic	0.805
NPC1	O15118-1.2	I1094R	Pathogenic	0.775
NPC1	O15118-1.2	I1094S	Pathogenic	0.792
NPC1	O15118-1.2	I1094T	Pathogenic	0.717
NPC1	O15118-1.2	I1094V	Neutral	0.409
NPC1	O15118-1.2	I1094W	Pathogenic	0.892
NPC1	O15118-1.2	I1094Y	Pathogenic	0.746
NPC1	O15118-1.2	I1095A	Neutral	0.435
NPC1	O15118-1.2	I1095C	Neutral	0.462
NPC1	O15118-1.2	I1095D	Pathogenic	0.502
NPC1	O15118-1.2	I1095E	Neutral	0.486
NPC1	O15118-1.2	I1095F	Neutral	0.394
NPC1	O15118-1.2	I1095G	Pathogenic	0.713
NPC1	O15118-1.2	I1095H	Pathogenic	0.536
NPC1	O15118-1.2	I1095K	Neutral	0.451
NPC1	O15118-1.2	I1095L	Neutral	0.214
NPC1	O15118-1.2	I1095M	Neutral	0.255
NPC1	O15118-1.2	I1095N	Pathogenic	0.508
NPC1	O15118-1.2	I1095P	Pathogenic	0.624
NPC1	O15118-1.2	I1095Q	Pathogenic	0.513
NPC1	O15118-1.2	I1095R	Neutral	0.469
NPC1	O15118-1.2	I1095S	Neutral	0.494
NPC1	O15118-1.2	I1095T	Neutral	0.393
NPC1	O15118-1.2	I1095V	Neutral	0.15
NPC1	O15118-1.2	I1095W	Pathogenic	0.679
NPC1	O15118-1.2	I1095Y	Neutral	0.429
NPC1	O15118-1.2	D1096A	Neutral	0.253
NPC1	O15118-1.2	D1096C	Neutral	0.262
NPC1	O15118-1.2	D1096E	Neutral	0.087
NPC1	O15118-1.2	D1096F	Neutral	0.255
NPC1	O15118-1.2	D1096G	Neutral	0.222
NPC1	O15118-1.2	D1096H	Neutral	0.199
NPC1	O15118-1.2	D1096I	Neutral	0.242
NPC1	O15118-1.2	D1096K	Neutral	0.257
NPC1	O15118-1.2	D1096L	Neutral	0.327
NPC1	O15118-1.2	D1096M	Neutral	0.279
NPC1	O15118-1.2	D1096N	Neutral	0.114
NPC1	O15118-1.2	D1096P	Neutral	0.149
NPC1	O15118-1.2	D1096Q	Neutral	0.156
NPC1	O15118-1.2	D1096R	Neutral	0.353
NPC1	O15118-1.2	D1096S	Neutral	0.145
NPC1	O15118-1.2	D1096T	Neutral	0.17
NPC1	O15118-1.2	D1096V	Neutral	0.257
NPC1	O15118-1.2	D1096W	Neutral	0.339
NPC1	O15118-1.2	D1096Y	Neutral	0.319
NPC1	O15118-1.2	D1097A	Pathogenic	0.94
NPC1	O15118-1.2	D1097C	Pathogenic	0.942
NPC1	O15118-1.2	D1097E	Pathogenic	0.815
NPC1	O15118-1.2	D1097F	Pathogenic	0.94
NPC1	O15118-1.2	D1097G	Pathogenic	0.929
NPC1	O15118-1.2	D1097H	Pathogenic	0.92
NPC1	O15118-1.2	D1097I	Pathogenic	0.936
NPC1	O15118-1.2	D1097K	Pathogenic	0.941
NPC1	O15118-1.2	D1097L	Pathogenic	0.957
NPC1	O15118-1.2	D1097M	Pathogenic	0.947
NPC1	O15118-1.2	D1097N	Pathogenic	0.855
NPC1	O15118-1.2	D1097P	Pathogenic	0.889
NPC1	O15118-1.2	D1097Q	Pathogenic	0.895
NPC1	O15118-1.2	D1097R	Pathogenic	0.962
NPC1	O15118-1.2	D1097S	Pathogenic	0.886
NPC1	O15118-1.2	D1097T	Pathogenic	0.904
NPC1	O15118-1.2	D1097V	Pathogenic	0.941
NPC1	O15118-1.2	D1097W	Pathogenic	0.959
NPC1	O15118-1.2	D1097Y	Pathogenic	0.956
NPC1	O15118-1.2	T1098A	Pathogenic	0.754
NPC1	O15118-1.2	T1098C	Pathogenic	0.763
NPC1	O15118-1.2	T1098D	Pathogenic	0.738
NPC1	O15118-1.2	T1098E	Pathogenic	0.762
NPC1	O15118-1.2	T1098F	Pathogenic	0.817
NPC1	O15118-1.2	T1098G	Pathogenic	0.874
NPC1	O15118-1.2	T1098H	Pathogenic	0.866
NPC1	O15118-1.2	T1098I	Pathogenic	0.739
NPC1	O15118-1.2	T1098K	Pathogenic	0.77
NPC1	O15118-1.2	T1098L	Pathogenic	0.745
NPC1	O15118-1.2	T1098M	Pathogenic	0.774
NPC1	O15118-1.2	T1098N	Pathogenic	0.671
NPC1	O15118-1.2	T1098P	Pathogenic	0.774
NPC1	O15118-1.2	T1098Q	Pathogenic	0.792
NPC1	O15118-1.2	T1098R	Pathogenic	0.783
NPC1	O15118-1.2	T1098S	Pathogenic	0.65
NPC1	O15118-1.2	T1098V	Pathogenic	0.676
NPC1	O15118-1.2	T1098W	Pathogenic	0.82
NPC1	O15118-1.2	T1098Y	Pathogenic	0.859
NPC1	O15118-1.2	I1099A	Neutral	0.189
NPC1	O15118-1.2	I1099C	Neutral	0.207
NPC1	O15118-1.2	I1099D	Neutral	0.234
NPC1	O15118-1.2	I1099E	Neutral	0.223
NPC1	O15118-1.2	I1099F	Neutral	0.164
NPC1	O15118-1.2	I1099G	Neutral	0.43
NPC1	O15118-1.2	I1099H	Neutral	0.259
NPC1	O15118-1.2	I1099K	Neutral	0.199
NPC1	O15118-1.2	I1099L	Neutral	0.076
NPC1	O15118-1.2	I1099M	Neutral	0.094
NPC1	O15118-1.2	I1099N	Neutral	0.239
NPC1	O15118-1.2	I1099P	Neutral	0.335
NPC1	O15118-1.2	I1099Q	Neutral	0.242
NPC1	O15118-1.2	I1099R	Neutral	0.211
NPC1	O15118-1.2	I1099S	Neutral	0.228
NPC1	O15118-1.2	I1099T	Neutral	0.164
NPC1	O15118-1.2	I1099V	Neutral	0.051
NPC1	O15118-1.2	I1099W	Neutral	0.391
NPC1	O15118-1.2	I1099Y	Neutral	0.186
NPC1	O15118-1.2	F1100A	Neutral	0.311
NPC1	O15118-1.2	F1100C	Neutral	0.335
NPC1	O15118-1.2	F1100D	Neutral	0.287
NPC1	O15118-1.2	F1100E	Neutral	0.273
NPC1	O15118-1.2	F1100G	Neutral	0.402
NPC1	O15118-1.2	F1100H	Neutral	0.175
NPC1	O15118-1.2	F1100I	Neutral	0.194
NPC1	O15118-1.2	F1100K	Neutral	0.222
NPC1	O15118-1.2	F1100L	Neutral	0.19
NPC1	O15118-1.2	F1100M	Neutral	0.167
NPC1	O15118-1.2	F1100N	Neutral	0.292
NPC1	O15118-1.2	F1100P	Neutral	0.494
NPC1	O15118-1.2	F1100Q	Neutral	0.296
NPC1	O15118-1.2	F1100R	Neutral	0.235
NPC1	O15118-1.2	F1100S	Neutral	0.28
NPC1	O15118-1.2	F1100T	Neutral	0.275
NPC1	O15118-1.2	F1100V	Neutral	0.248
NPC1	O15118-1.2	F1100W	Neutral	0.135
NPC1	O15118-1.2	F1100Y	Neutral	0.053
NPC1	O15118-1.2	N1101A	Pathogenic	0.558
NPC1	O15118-1.2	N1101C	Pathogenic	0.57
NPC1	O15118-1.2	N1101D	Neutral	0.305
NPC1	O15118-1.2	N1101E	Neutral	0.415
NPC1	O15118-1.2	N1101F	Pathogenic	0.547
NPC1	O15118-1.2	N1101G	Neutral	0.421
NPC1	O15118-1.2	N1101H	Neutral	0.288
NPC1	O15118-1.2	N1101I	Pathogenic	0.529
NPC1	O15118-1.2	N1101K	Neutral	0.425
NPC1	O15118-1.2	N1101L	Pathogenic	0.538
NPC1	O15118-1.2	N1101M	Neutral	0.48
NPC1	O15118-1.2	N1101P	Neutral	0.49
NPC1	O15118-1.2	N1101Q	Neutral	0.394
NPC1	O15118-1.2	N1101R	Neutral	0.443
NPC1	O15118-1.2	N1101S	Neutral	0.3
NPC1	O15118-1.2	N1101T	Neutral	0.337
NPC1	O15118-1.2	N1101V	Pathogenic	0.549
NPC1	O15118-1.2	N1101W	Pathogenic	0.643
NPC1	O15118-1.2	N1101Y	Pathogenic	0.528
NPC1	O15118-1.2	L1102A	Neutral	0.447
NPC1	O15118-1.2	L1102C	Neutral	0.474
NPC1	O15118-1.2	L1102D	Pathogenic	0.608
NPC1	O15118-1.2	L1102E	Neutral	0.498
NPC1	O15118-1.2	L1102F	Neutral	0.391
NPC1	O15118-1.2	L1102G	Pathogenic	0.723
NPC1	O15118-1.2	L1102H	Pathogenic	0.548
NPC1	O15118-1.2	L1102I	Neutral	0.216
NPC1	O15118-1.2	L1102K	Neutral	0.369
NPC1	O15118-1.2	L1102M	Neutral	0.196
NPC1	O15118-1.2	L1102N	Pathogenic	0.52
NPC1	O15118-1.2	L1102P	Pathogenic	0.635
NPC1	O15118-1.2	L1102Q	Neutral	0.429
NPC1	O15118-1.2	L1102R	Neutral	0.386
NPC1	O15118-1.2	L1102S	Pathogenic	0.505
NPC1	O15118-1.2	L1102T	Neutral	0.404
NPC1	O15118-1.2	L1102V	Neutral	0.286
NPC1	O15118-1.2	L1102W	Pathogenic	0.585
NPC1	O15118-1.2	L1102Y	Neutral	0.441
NPC1	O15118-1.2	G1103A	Neutral	0.19
NPC1	O15118-1.2	G1103C	Neutral	0.4
NPC1	O15118-1.2	G1103D	Neutral	0.254
NPC1	O15118-1.2	G1103E	Neutral	0.369
NPC1	O15118-1.2	G1103F	Neutral	0.407
NPC1	O15118-1.2	G1103H	Neutral	0.422
NPC1	O15118-1.2	G1103I	Neutral	0.485
NPC1	O15118-1.2	G1103K	Neutral	0.378
NPC1	O15118-1.2	G1103L	Neutral	0.493
NPC1	O15118-1.2	G1103M	Neutral	0.436
NPC1	O15118-1.2	G1103N	Neutral	0.202
NPC1	O15118-1.2	G1103P	Neutral	0.337
NPC1	O15118-1.2	G1103Q	Neutral	0.409
NPC1	O15118-1.2	G1103R	Neutral	0.396
NPC1	O15118-1.2	G1103S	Neutral	0.21
NPC1	O15118-1.2	G1103T	Neutral	0.376
NPC1	O15118-1.2	G1103V	Neutral	0.409
NPC1	O15118-1.2	G1103W	Neutral	0.322
NPC1	O15118-1.2	G1103Y	Neutral	0.484
NPC1	O15118-1.2	V1104A	Neutral	0.196
NPC1	O15118-1.2	V1104C	Neutral	0.285
NPC1	O15118-1.2	V1104D	Neutral	0.319
NPC1	O15118-1.2	V1104E	Neutral	0.238
NPC1	O15118-1.2	V1104F	Neutral	0.276
NPC1	O15118-1.2	V1104G	Neutral	0.44
NPC1	O15118-1.2	V1104H	Neutral	0.386
NPC1	O15118-1.2	V1104I	Neutral	0.071
NPC1	O15118-1.2	V1104K	Neutral	0.246
NPC1	O15118-1.2	V1104L	Neutral	0.145
NPC1	O15118-1.2	V1104M	Neutral	0.166
NPC1	O15118-1.2	V1104N	Neutral	0.325
NPC1	O15118-1.2	V1104P	Neutral	0.344
NPC1	O15118-1.2	V1104Q	Neutral	0.27
NPC1	O15118-1.2	V1104R	Neutral	0.34
NPC1	O15118-1.2	V1104S	Neutral	0.312
NPC1	O15118-1.2	V1104T	Neutral	0.17
NPC1	O15118-1.2	V1104W	Neutral	0.456
NPC1	O15118-1.2	V1104Y	Neutral	0.305
NPC1	O15118-1.2	S1105A	Neutral	0.469
NPC1	O15118-1.2	S1105C	Pathogenic	0.614
NPC1	O15118-1.2	S1105D	Pathogenic	0.551
NPC1	O15118-1.2	S1105E	Pathogenic	0.588
NPC1	O15118-1.2	S1105F	Pathogenic	0.707
NPC1	O15118-1.2	S1105G	Pathogenic	0.617
NPC1	O15118-1.2	S1105H	Pathogenic	0.719
NPC1	O15118-1.2	S1105I	Pathogenic	0.692
NPC1	O15118-1.2	S1105K	Pathogenic	0.598
NPC1	O15118-1.2	S1105L	Pathogenic	0.699
NPC1	O15118-1.2	S1105M	Pathogenic	0.648
NPC1	O15118-1.2	S1105N	Neutral	0.476
NPC1	O15118-1.2	S1105P	Pathogenic	0.64
NPC1	O15118-1.2	S1105Q	Pathogenic	0.629
NPC1	O15118-1.2	S1105R	Pathogenic	0.702
NPC1	O15118-1.2	S1105T	Neutral	0.494
NPC1	O15118-1.2	S1105V	Pathogenic	0.708
NPC1	O15118-1.2	S1105W	Pathogenic	0.783
NPC1	O15118-1.2	S1105Y	Pathogenic	0.767
NPC1	O15118-1.2	L1106A	Neutral	0.495
NPC1	O15118-1.2	L1106C	Pathogenic	0.522
NPC1	O15118-1.2	L1106D	Pathogenic	0.654
NPC1	O15118-1.2	L1106E	Pathogenic	0.546
NPC1	O15118-1.2	L1106F	Neutral	0.438
NPC1	O15118-1.2	L1106G	Pathogenic	0.76
NPC1	O15118-1.2	L1106H	Pathogenic	0.595
NPC1	O15118-1.2	L1106I	Neutral	0.251
NPC1	O15118-1.2	L1106K	Neutral	0.415
NPC1	O15118-1.2	L1106M	Neutral	0.229
NPC1	O15118-1.2	L1106N	Pathogenic	0.568
NPC1	O15118-1.2	L1106P	Pathogenic	0.679
NPC1	O15118-1.2	L1106Q	Neutral	0.477
NPC1	O15118-1.2	L1106R	Neutral	0.433
NPC1	O15118-1.2	L1106S	Pathogenic	0.554
NPC1	O15118-1.2	L1106T	Neutral	0.452
NPC1	O15118-1.2	L1106V	Neutral	0.328
NPC1	O15118-1.2	L1106W	Pathogenic	0.631
NPC1	O15118-1.2	L1106Y	Neutral	0.489
NPC1	O15118-1.2	G1107A	Neutral	0.174
NPC1	O15118-1.2	G1107C	Neutral	0.375
NPC1	O15118-1.2	G1107D	Neutral	0.234
NPC1	O15118-1.2	G1107E	Neutral	0.344
NPC1	O15118-1.2	G1107F	Neutral	0.381
NPC1	O15118-1.2	G1107H	Neutral	0.396
NPC1	O15118-1.2	G1107I	Neutral	0.458
NPC1	O15118-1.2	G1107K	Neutral	0.353
NPC1	O15118-1.2	G1107L	Neutral	0.466
NPC1	O15118-1.2	G1107M	Neutral	0.41
NPC1	O15118-1.2	G1107N	Neutral	0.185
NPC1	O15118-1.2	G1107P	Neutral	0.313
NPC1	O15118-1.2	G1107Q	Neutral	0.383
NPC1	O15118-1.2	G1107R	Neutral	0.37
NPC1	O15118-1.2	G1107S	Neutral	0.192
NPC1	O15118-1.2	G1107T	Neutral	0.351
NPC1	O15118-1.2	G1107V	Neutral	0.383
NPC1	O15118-1.2	G1107W	Neutral	0.299
NPC1	O15118-1.2	G1107Y	Neutral	0.457
NPC1	O15118-1.2	A1108C	Neutral	0.348
NPC1	O15118-1.2	A1108D	Pathogenic	0.51
NPC1	O15118-1.2	A1108E	Neutral	0.452
NPC1	O15118-1.2	A1108F	Pathogenic	0.543
NPC1	O15118-1.2	A1108G	Neutral	0.376
NPC1	O15118-1.2	A1108H	Pathogenic	0.623
NPC1	O15118-1.2	A1108I	Neutral	0.43
NPC1	O15118-1.2	A1108K	Neutral	0.462
NPC1	O15118-1.2	A1108L	Neutral	0.438
NPC1	O15118-1.2	A1108M	Neutral	0.477
NPC1	O15118-1.2	A1108N	Pathogenic	0.532
NPC1	O15118-1.2	A1108P	Neutral	0.468
NPC1	O15118-1.2	A1108Q	Neutral	0.494
NPC1	O15118-1.2	A1108R	Neutral	0.481
NPC1	O15118-1.2	A1108S	Neutral	0.273
NPC1	O15118-1.2	A1108T	Neutral	0.407
NPC1	O15118-1.2	A1108V	Neutral	0.357
NPC1	O15118-1.2	A1108W	Pathogenic	0.64
NPC1	O15118-1.2	A1108Y	Pathogenic	0.619
NPC1	O15118-1.2	I1109A	Pathogenic	0.627
NPC1	O15118-1.2	I1109C	Pathogenic	0.652
NPC1	O15118-1.2	I1109D	Pathogenic	0.687
NPC1	O15118-1.2	I1109E	Pathogenic	0.673
NPC1	O15118-1.2	I1109F	Pathogenic	0.586
NPC1	O15118-1.2	I1109G	Pathogenic	0.844
NPC1	O15118-1.2	I1109H	Pathogenic	0.716
NPC1	O15118-1.2	I1109K	Pathogenic	0.641
NPC1	O15118-1.2	I1109L	Neutral	0.373
NPC1	O15118-1.2	I1109M	Neutral	0.428
NPC1	O15118-1.2	I1109N	Pathogenic	0.693
NPC1	O15118-1.2	I1109P	Pathogenic	0.784
NPC1	O15118-1.2	I1109Q	Pathogenic	0.697
NPC1	O15118-1.2	I1109R	Pathogenic	0.658
NPC1	O15118-1.2	I1109S	Pathogenic	0.68
NPC1	O15118-1.2	I1109T	Pathogenic	0.585
NPC1	O15118-1.2	I1109V	Neutral	0.279
NPC1	O15118-1.2	I1109W	Pathogenic	0.822
NPC1	O15118-1.2	I1109Y	Pathogenic	0.621
NPC1	O15118-1.2	F1110A	Pathogenic	0.873
NPC1	O15118-1.2	F1110C	Pathogenic	0.885
NPC1	O15118-1.2	F1110D	Pathogenic	0.859
NPC1	O15118-1.2	F1110E	Pathogenic	0.851
NPC1	O15118-1.2	F1110G	Pathogenic	0.911
NPC1	O15118-1.2	F1110H	Pathogenic	0.764
NPC1	O15118-1.2	F1110I	Pathogenic	0.786
NPC1	O15118-1.2	F1110K	Pathogenic	0.813
NPC1	O15118-1.2	F1110L	Pathogenic	0.781
NPC1	O15118-1.2	F1110M	Pathogenic	0.754
NPC1	O15118-1.2	F1110N	Pathogenic	0.862
NPC1	O15118-1.2	F1110P	Pathogenic	0.937
NPC1	O15118-1.2	F1110Q	Pathogenic	0.865
NPC1	O15118-1.2	F1110R	Pathogenic	0.824
NPC1	O15118-1.2	F1110S	Pathogenic	0.855
NPC1	O15118-1.2	F1110T	Pathogenic	0.852
NPC1	O15118-1.2	F1110V	Pathogenic	0.834
NPC1	O15118-1.2	F1110W	Pathogenic	0.704
NPC1	O15118-1.2	F1110Y	Neutral	0.46
NPC1	O15118-1.2	L1111A	Neutral	0.208
NPC1	O15118-1.2	L1111C	Neutral	0.226
NPC1	O15118-1.2	L1111D	Neutral	0.335
NPC1	O15118-1.2	L1111E	Neutral	0.243
NPC1	O15118-1.2	L1111F	Neutral	0.172
NPC1	O15118-1.2	L1111G	Neutral	0.458
NPC1	O15118-1.2	L1111H	Neutral	0.282
NPC1	O15118-1.2	L1111I	Neutral	0.082
NPC1	O15118-1.2	L1111K	Neutral	0.159
NPC1	O15118-1.2	L1111M	Neutral	0.073
NPC1	O15118-1.2	L1111N	Neutral	0.26
NPC1	O15118-1.2	L1111P	Neutral	0.361
NPC1	O15118-1.2	L1111Q	Neutral	0.196
NPC1	O15118-1.2	L1111R	Neutral	0.169
NPC1	O15118-1.2	L1111S	Neutral	0.249
NPC1	O15118-1.2	L1111T	Neutral	0.18
NPC1	O15118-1.2	L1111V	Neutral	0.115
NPC1	O15118-1.2	L1111W	Neutral	0.314
NPC1	O15118-1.2	L1111Y	Neutral	0.204
NPC1	O15118-1.2	V1112A	Pathogenic	0.641
NPC1	O15118-1.2	V1112C	Pathogenic	0.746
NPC1	O15118-1.2	V1112D	Pathogenic	0.775
NPC1	O15118-1.2	V1112E	Pathogenic	0.697
NPC1	O15118-1.2	V1112F	Pathogenic	0.737
NPC1	O15118-1.2	V1112G	Pathogenic	0.852
NPC1	O15118-1.2	V1112H	Pathogenic	0.822
NPC1	O15118-1.2	V1112I	Neutral	0.358
NPC1	O15118-1.2	V1112K	Pathogenic	0.705
NPC1	O15118-1.2	V1112L	Pathogenic	0.555
NPC1	O15118-1.2	V1112M	Pathogenic	0.593
NPC1	O15118-1.2	V1112N	Pathogenic	0.779
NPC1	O15118-1.2	V1112P	Pathogenic	0.794
NPC1	O15118-1.2	V1112Q	Pathogenic	0.731
NPC1	O15118-1.2	V1112R	Pathogenic	0.791
NPC1	O15118-1.2	V1112S	Pathogenic	0.769
NPC1	O15118-1.2	V1112T	Pathogenic	0.6
NPC1	O15118-1.2	V1112W	Pathogenic	0.86
NPC1	O15118-1.2	V1112Y	Pathogenic	0.763
NPC1	O15118-1.2	T1113A	Neutral	0.434
NPC1	O15118-1.2	T1113C	Neutral	0.446
NPC1	O15118-1.2	T1113D	Neutral	0.414
NPC1	O15118-1.2	T1113E	Neutral	0.445
NPC1	O15118-1.2	T1113F	Pathogenic	0.528
NPC1	O15118-1.2	T1113G	Pathogenic	0.635
NPC1	O15118-1.2	T1113H	Pathogenic	0.617
NPC1	O15118-1.2	T1113I	Neutral	0.414
NPC1	O15118-1.2	T1113K	Neutral	0.455
NPC1	O15118-1.2	T1113L	Neutral	0.423
NPC1	O15118-1.2	T1113M	Neutral	0.461
NPC1	O15118-1.2	T1113N	Neutral	0.338
NPC1	O15118-1.2	T1113P	Neutral	0.461
NPC1	O15118-1.2	T1113Q	Neutral	0.487
NPC1	O15118-1.2	T1113R	Neutral	0.474
NPC1	O15118-1.2	T1113S	Neutral	0.317
NPC1	O15118-1.2	T1113V	Neutral	0.343
NPC1	O15118-1.2	T1113W	Pathogenic	0.532
NPC1	O15118-1.2	T1113Y	Pathogenic	0.604
NPC1	O15118-1.2	M1114A	Neutral	0.154
NPC1	O15118-1.2	M1114C	Neutral	0.169
NPC1	O15118-1.2	M1114D	Neutral	0.192
NPC1	O15118-1.2	M1114E	Neutral	0.132
NPC1	O15118-1.2	M1114F	Neutral	0.096
NPC1	O15118-1.2	M1114G	Neutral	0.285
NPC1	O15118-1.2	M1114H	Neutral	0.157
NPC1	O15118-1.2	M1114I	Neutral	0.063
NPC1	O15118-1.2	M1114K	Neutral	0.082
NPC1	O15118-1.2	M1114L	Neutral	0.045
NPC1	O15118-1.2	M1114N	Neutral	0.143
NPC1	O15118-1.2	M1114P	Neutral	0.211
NPC1	O15118-1.2	M1114Q	Neutral	0.073
NPC1	O15118-1.2	M1114R	Neutral	0.088
NPC1	O15118-1.2	M1114S	Neutral	0.136
NPC1	O15118-1.2	M1114T	Neutral	0.133
NPC1	O15118-1.2	M1114V	Neutral	0.083
NPC1	O15118-1.2	M1114W	Neutral	0.137
NPC1	O15118-1.2	M1114Y	Neutral	0.151
NPC1	O15118-1.2	V1115A	Neutral	0.215
NPC1	O15118-1.2	V1115C	Neutral	0.309
NPC1	O15118-1.2	V1115D	Neutral	0.344
NPC1	O15118-1.2	V1115E	Neutral	0.26
NPC1	O15118-1.2	V1115F	Neutral	0.3
NPC1	O15118-1.2	V1115G	Neutral	0.468
NPC1	O15118-1.2	V1115H	Neutral	0.413
NPC1	O15118-1.2	V1115I	Neutral	0.079
NPC1	O15118-1.2	V1115K	Neutral	0.268
NPC1	O15118-1.2	V1115L	Neutral	0.16
NPC1	O15118-1.2	V1115M	Neutral	0.182
NPC1	O15118-1.2	V1115N	Neutral	0.35
NPC1	O15118-1.2	V1115P	Neutral	0.371
NPC1	O15118-1.2	V1115Q	Neutral	0.294
NPC1	O15118-1.2	V1115R	Neutral	0.367
NPC1	O15118-1.2	V1115S	Neutral	0.337
NPC1	O15118-1.2	V1115T	Neutral	0.187
NPC1	O15118-1.2	V1115W	Neutral	0.485
NPC1	O15118-1.2	V1115Y	Neutral	0.33
NPC1	O15118-1.2	L1116A	Pathogenic	0.708
NPC1	O15118-1.2	L1116C	Pathogenic	0.73
NPC1	O15118-1.2	L1116D	Pathogenic	0.824
NPC1	O15118-1.2	L1116E	Pathogenic	0.748
NPC1	O15118-1.2	L1116F	Pathogenic	0.658
NPC1	O15118-1.2	L1116G	Pathogenic	0.887
NPC1	O15118-1.2	L1116H	Pathogenic	0.784
NPC1	O15118-1.2	L1116I	Neutral	0.453
NPC1	O15118-1.2	L1116K	Pathogenic	0.637
NPC1	O15118-1.2	L1116M	Neutral	0.423
NPC1	O15118-1.2	L1116N	Pathogenic	0.765
NPC1	O15118-1.2	L1116P	Pathogenic	0.84
NPC1	O15118-1.2	L1116Q	Pathogenic	0.693
NPC1	O15118-1.2	L1116R	Pathogenic	0.654
NPC1	O15118-1.2	L1116S	Pathogenic	0.754
NPC1	O15118-1.2	L1116T	Pathogenic	0.671
NPC1	O15118-1.2	L1116V	Pathogenic	0.547
NPC1	O15118-1.2	L1116W	Pathogenic	0.809
NPC1	O15118-1.2	L1116Y	Pathogenic	0.703
NPC1	O15118-1.2	L1117A	Pathogenic	0.557
NPC1	O15118-1.2	L1117C	Pathogenic	0.584
NPC1	O15118-1.2	L1117D	Pathogenic	0.707
NPC1	O15118-1.2	L1117E	Pathogenic	0.606
NPC1	O15118-1.2	L1117F	Neutral	0.499
NPC1	O15118-1.2	L1117G	Pathogenic	0.802
NPC1	O15118-1.2	L1117H	Pathogenic	0.653
NPC1	O15118-1.2	L1117I	Neutral	0.3
NPC1	O15118-1.2	L1117K	Neutral	0.476
NPC1	O15118-1.2	L1117M	Neutral	0.275
NPC1	O15118-1.2	L1117N	Pathogenic	0.628
NPC1	O15118-1.2	L1117P	Pathogenic	0.73
NPC1	O15118-1.2	L1117Q	Pathogenic	0.538
NPC1	O15118-1.2	L1117R	Neutral	0.495
NPC1	O15118-1.2	L1117S	Pathogenic	0.614
NPC1	O15118-1.2	L1117T	Pathogenic	0.513
NPC1	O15118-1.2	L1117V	Neutral	0.384
NPC1	O15118-1.2	L1117W	Pathogenic	0.687
NPC1	O15118-1.2	L1117Y	Pathogenic	0.551
NPC1	O15118-1.2	G1118A	Pathogenic	0.78
NPC1	O15118-1.2	G1118C	Pathogenic	0.91
NPC1	O15118-1.2	G1118D	Pathogenic	0.838
NPC1	O15118-1.2	G1118E	Pathogenic	0.899
NPC1	O15118-1.2	G1118F	Pathogenic	0.912
NPC1	O15118-1.2	G1118H	Pathogenic	0.917
NPC1	O15118-1.2	G1118I	Pathogenic	0.934
NPC1	O15118-1.2	G1118K	Pathogenic	0.902
NPC1	O15118-1.2	G1118L	Pathogenic	0.937
NPC1	O15118-1.2	G1118M	Pathogenic	0.921
NPC1	O15118-1.2	G1118N	Pathogenic	0.793
NPC1	O15118-1.2	G1118P	Pathogenic	0.885
NPC1	O15118-1.2	G1118Q	Pathogenic	0.913
NPC1	O15118-1.2	G1118R	Pathogenic	0.909
NPC1	O15118-1.2	G1118S	Pathogenic	0.801
NPC1	O15118-1.2	G1118T	Pathogenic	0.901
NPC1	O15118-1.2	G1118V	Pathogenic	0.913
NPC1	O15118-1.2	G1118W	Pathogenic	0.878
NPC1	O15118-1.2	G1118Y	Pathogenic	0.934
NPC1	O15118-1.2	C1119A	Neutral	0.233
NPC1	O15118-1.2	C1119D	Neutral	0.382
NPC1	O15118-1.2	C1119E	Pathogenic	0.515
NPC1	O15118-1.2	C1119F	Neutral	0.429
NPC1	O15118-1.2	C1119G	Neutral	0.494
NPC1	O15118-1.2	C1119H	Neutral	0.496
NPC1	O15118-1.2	C1119I	Neutral	0.323
NPC1	O15118-1.2	C1119K	Neutral	0.429
NPC1	O15118-1.2	C1119L	Neutral	0.33
NPC1	O15118-1.2	C1119M	Neutral	0.366
NPC1	O15118-1.2	C1119N	Neutral	0.403
NPC1	O15118-1.2	C1119P	Pathogenic	0.502
NPC1	O15118-1.2	C1119Q	Neutral	0.461
NPC1	O15118-1.2	C1119R	Neutral	0.447
NPC1	O15118-1.2	C1119S	Neutral	0.277
NPC1	O15118-1.2	C1119T	Neutral	0.29
NPC1	O15118-1.2	C1119V	Neutral	0.34
NPC1	O15118-1.2	C1119W	Neutral	0.433
NPC1	O15118-1.2	C1119Y	Pathogenic	0.503
NPC1	O15118-1.2	E1120A	Pathogenic	0.809
NPC1	O15118-1.2	E1120C	Pathogenic	0.906
NPC1	O15118-1.2	E1120D	Pathogenic	0.602
NPC1	O15118-1.2	E1120F	Pathogenic	0.836
NPC1	O15118-1.2	E1120G	Pathogenic	0.886
NPC1	O15118-1.2	E1120H	Pathogenic	0.715
NPC1	O15118-1.2	E1120I	Pathogenic	0.826
NPC1	O15118-1.2	E1120K	Pathogenic	0.685
NPC1	O15118-1.2	E1120L	Pathogenic	0.831
NPC1	O15118-1.2	E1120M	Pathogenic	0.796
NPC1	O15118-1.2	E1120N	Pathogenic	0.766
NPC1	O15118-1.2	E1120P	Pathogenic	0.763
NPC1	O15118-1.2	E1120Q	Pathogenic	0.56
NPC1	O15118-1.2	E1120R	Pathogenic	0.775
NPC1	O15118-1.2	E1120S	Pathogenic	0.757
NPC1	O15118-1.2	E1120T	Pathogenic	0.787
NPC1	O15118-1.2	E1120V	Pathogenic	0.786
NPC1	O15118-1.2	E1120W	Pathogenic	0.838
NPC1	O15118-1.2	E1120Y	Pathogenic	0.826
NPC1	O15118-1.2	L1121A	Pathogenic	0.554
NPC1	O15118-1.2	L1121C	Pathogenic	0.581
NPC1	O15118-1.2	L1121D	Pathogenic	0.705
NPC1	O15118-1.2	L1121E	Pathogenic	0.603
NPC1	O15118-1.2	L1121F	Neutral	0.496
NPC1	O15118-1.2	L1121G	Pathogenic	0.8
NPC1	O15118-1.2	L1121H	Pathogenic	0.65
NPC1	O15118-1.2	L1121I	Neutral	0.298
NPC1	O15118-1.2	L1121K	Neutral	0.473
NPC1	O15118-1.2	L1121M	Neutral	0.273
NPC1	O15118-1.2	L1121N	Pathogenic	0.625
NPC1	O15118-1.2	L1121P	Pathogenic	0.728
NPC1	O15118-1.2	L1121Q	Pathogenic	0.535
NPC1	O15118-1.2	L1121R	Neutral	0.492
NPC1	O15118-1.2	L1121S	Pathogenic	0.611
NPC1	O15118-1.2	L1121T	Pathogenic	0.51
NPC1	O15118-1.2	L1121V	Neutral	0.381
NPC1	O15118-1.2	L1121W	Pathogenic	0.684
NPC1	O15118-1.2	L1121Y	Pathogenic	0.548
NPC1	O15118-1.2	W1122A	Pathogenic	0.765
NPC1	O15118-1.2	W1122C	Pathogenic	0.712
NPC1	O15118-1.2	W1122D	Pathogenic	0.743
NPC1	O15118-1.2	W1122E	Pathogenic	0.648
NPC1	O15118-1.2	W1122F	Neutral	0.43
NPC1	O15118-1.2	W1122G	Pathogenic	0.691
NPC1	O15118-1.2	W1122H	Pathogenic	0.605
NPC1	O15118-1.2	W1122I	Pathogenic	0.791
NPC1	O15118-1.2	W1122K	Pathogenic	0.584
NPC1	O15118-1.2	W1122L	Pathogenic	0.714
NPC1	O15118-1.2	W1122M	Pathogenic	0.592
NPC1	O15118-1.2	W1122N	Pathogenic	0.748
NPC1	O15118-1.2	W1122P	Pathogenic	0.827
NPC1	O15118-1.2	W1122Q	Pathogenic	0.583
NPC1	O15118-1.2	W1122R	Pathogenic	0.563
NPC1	O15118-1.2	W1122S	Pathogenic	0.737
NPC1	O15118-1.2	W1122T	Pathogenic	0.65
NPC1	O15118-1.2	W1122V	Pathogenic	0.778
NPC1	O15118-1.2	W1122Y	Neutral	0.273
NPC1	O15118-1.2	S1123A	Pathogenic	0.662
NPC1	O15118-1.2	S1123C	Pathogenic	0.779
NPC1	O15118-1.2	S1123D	Pathogenic	0.731
NPC1	O15118-1.2	S1123E	Pathogenic	0.76
NPC1	O15118-1.2	S1123F	Pathogenic	0.842
NPC1	O15118-1.2	S1123G	Pathogenic	0.781
NPC1	O15118-1.2	S1123H	Pathogenic	0.85
NPC1	O15118-1.2	S1123I	Pathogenic	0.832
NPC1	O15118-1.2	S1123K	Pathogenic	0.767
NPC1	O15118-1.2	S1123L	Pathogenic	0.837
NPC1	O15118-1.2	S1123M	Pathogenic	0.803
NPC1	O15118-1.2	S1123N	Pathogenic	0.668
NPC1	O15118-1.2	S1123P	Pathogenic	0.798
NPC1	O15118-1.2	S1123Q	Pathogenic	0.789
NPC1	O15118-1.2	S1123R	Pathogenic	0.839
NPC1	O15118-1.2	S1123T	Pathogenic	0.684
NPC1	O15118-1.2	S1123V	Pathogenic	0.843
NPC1	O15118-1.2	S1123W	Pathogenic	0.889
NPC1	O15118-1.2	S1123Y	Pathogenic	0.879
NPC1	O15118-1.2	A1124C	Pathogenic	0.692
NPC1	O15118-1.2	A1124D	Pathogenic	0.814
NPC1	O15118-1.2	A1124E	Pathogenic	0.776
NPC1	O15118-1.2	A1124F	Pathogenic	0.833
NPC1	O15118-1.2	A1124G	Pathogenic	0.717
NPC1	O15118-1.2	A1124H	Pathogenic	0.874
NPC1	O15118-1.2	A1124I	Pathogenic	0.76
NPC1	O15118-1.2	A1124K	Pathogenic	0.783
NPC1	O15118-1.2	A1124L	Pathogenic	0.766
NPC1	O15118-1.2	A1124M	Pathogenic	0.793
NPC1	O15118-1.2	A1124N	Pathogenic	0.827
NPC1	O15118-1.2	A1124P	Pathogenic	0.787
NPC1	O15118-1.2	A1124Q	Pathogenic	0.804
NPC1	O15118-1.2	A1124R	Pathogenic	0.795
NPC1	O15118-1.2	A1124S	Pathogenic	0.612
NPC1	O15118-1.2	A1124T	Pathogenic	0.742
NPC1	O15118-1.2	A1124V	Pathogenic	0.7
NPC1	O15118-1.2	A1124W	Pathogenic	0.882
NPC1	O15118-1.2	A1124Y	Pathogenic	0.872
NPC1	O15118-1.2	V1125A	Neutral	0.161
NPC1	O15118-1.2	V1125C	Neutral	0.239
NPC1	O15118-1.2	V1125D	Neutral	0.269
NPC1	O15118-1.2	V1125E	Neutral	0.198
NPC1	O15118-1.2	V1125F	Neutral	0.231
NPC1	O15118-1.2	V1125G	Neutral	0.382
NPC1	O15118-1.2	V1125H	Neutral	0.331
NPC1	O15118-1.2	V1125I	Neutral	0.056
NPC1	O15118-1.2	V1125K	Neutral	0.204
NPC1	O15118-1.2	V1125L	Neutral	0.118
NPC1	O15118-1.2	V1125M	Neutral	0.135
NPC1	O15118-1.2	V1125N	Neutral	0.274
NPC1	O15118-1.2	V1125P	Neutral	0.292
NPC1	O15118-1.2	V1125Q	Neutral	0.226
NPC1	O15118-1.2	V1125R	Neutral	0.289
NPC1	O15118-1.2	V1125S	Neutral	0.263
NPC1	O15118-1.2	V1125T	Neutral	0.139
NPC1	O15118-1.2	V1125W	Neutral	0.398
NPC1	O15118-1.2	V1125Y	Neutral	0.257
NPC1	O15118-1.2	I1126A	Neutral	0.245
NPC1	O15118-1.2	I1126C	Neutral	0.266
NPC1	O15118-1.2	I1126D	Neutral	0.298
NPC1	O15118-1.2	I1126E	Neutral	0.285
NPC1	O15118-1.2	I1126F	Neutral	0.215
NPC1	O15118-1.2	I1126G	Pathogenic	0.511
NPC1	O15118-1.2	I1126H	Neutral	0.328
NPC1	O15118-1.2	I1126K	Neutral	0.257
NPC1	O15118-1.2	I1126L	Neutral	0.103
NPC1	O15118-1.2	I1126M	Neutral	0.126
NPC1	O15118-1.2	I1126N	Neutral	0.304
NPC1	O15118-1.2	I1126P	Neutral	0.412
NPC1	O15118-1.2	I1126Q	Neutral	0.307
NPC1	O15118-1.2	I1126R	Neutral	0.271
NPC1	O15118-1.2	I1126S	Neutral	0.291
NPC1	O15118-1.2	I1126T	Neutral	0.214
NPC1	O15118-1.2	I1126V	Neutral	0.069
NPC1	O15118-1.2	I1126W	Neutral	0.472
NPC1	O15118-1.2	I1126Y	Neutral	0.241
NPC1	O15118-1.2	M1127A	Neutral	0.373
NPC1	O15118-1.2	M1127C	Neutral	0.399
NPC1	O15118-1.2	M1127D	Neutral	0.437
NPC1	O15118-1.2	M1127E	Neutral	0.331
NPC1	O15118-1.2	M1127F	Neutral	0.257
NPC1	O15118-1.2	M1127G	Pathogenic	0.566
NPC1	O15118-1.2	M1127H	Neutral	0.377
NPC1	O15118-1.2	M1127I	Neutral	0.18
NPC1	O15118-1.2	M1127K	Neutral	0.226
NPC1	O15118-1.2	M1127L	Neutral	0.133
NPC1	O15118-1.2	M1127N	Neutral	0.352
NPC1	O15118-1.2	M1127P	Neutral	0.466
NPC1	O15118-1.2	M1127Q	Neutral	0.203
NPC1	O15118-1.2	M1127R	Neutral	0.239
NPC1	O15118-1.2	M1127S	Neutral	0.338
NPC1	O15118-1.2	M1127T	Neutral	0.333
NPC1	O15118-1.2	M1127V	Neutral	0.228
NPC1	O15118-1.2	M1127W	Neutral	0.341
NPC1	O15118-1.2	M1127Y	Neutral	0.367
NPC1	O15118-1.2	C1128A	Neutral	0.114
NPC1	O15118-1.2	C1128D	Neutral	0.209
NPC1	O15118-1.2	C1128E	Neutral	0.311
NPC1	O15118-1.2	C1128F	Neutral	0.243
NPC1	O15118-1.2	C1128G	Neutral	0.294
NPC1	O15118-1.2	C1128H	Neutral	0.295
NPC1	O15118-1.2	C1128I	Neutral	0.169
NPC1	O15118-1.2	C1128K	Neutral	0.242
NPC1	O15118-1.2	C1128L	Neutral	0.174
NPC1	O15118-1.2	C1128M	Neutral	0.197
NPC1	O15118-1.2	C1128N	Neutral	0.223
NPC1	O15118-1.2	C1128P	Neutral	0.301
NPC1	O15118-1.2	C1128Q	Neutral	0.267
NPC1	O15118-1.2	C1128R	Neutral	0.256
NPC1	O15118-1.2	C1128S	Neutral	0.14
NPC1	O15118-1.2	C1128T	Neutral	0.148
NPC1	O15118-1.2	C1128V	Neutral	0.18
NPC1	O15118-1.2	C1128W	Neutral	0.246
NPC1	O15118-1.2	C1128Y	Neutral	0.301
NPC1	O15118-1.2	A1129C	Neutral	0.07
NPC1	O15118-1.2	A1129D	Neutral	0.127
NPC1	O15118-1.2	A1129E	Neutral	0.104
NPC1	O15118-1.2	A1129F	Neutral	0.143
NPC1	O15118-1.2	A1129G	Neutral	0.078
NPC1	O15118-1.2	A1129H	Neutral	0.188
NPC1	O15118-1.2	A1129I	Neutral	0.095
NPC1	O15118-1.2	A1129K	Neutral	0.107
NPC1	O15118-1.2	A1129L	Neutral	0.098
NPC1	O15118-1.2	A1129M	Neutral	0.113
NPC1	O15118-1.2	A1129N	Neutral	0.137
NPC1	O15118-1.2	A1129P	Neutral	0.11
NPC1	O15118-1.2	A1129Q	Neutral	0.12
NPC1	O15118-1.2	A1129R	Neutral	0.115
NPC1	O15118-1.2	A1129S	Neutral	0.05
NPC1	O15118-1.2	A1129T	Neutral	0.088
NPC1	O15118-1.2	A1129V	Neutral	0.072
NPC1	O15118-1.2	A1129W	Neutral	0.199
NPC1	O15118-1.2	A1129Y	Neutral	0.185
NPC1	O15118-1.2	T1130A	Pathogenic	0.815
NPC1	O15118-1.2	T1130C	Pathogenic	0.822
NPC1	O15118-1.2	T1130D	Pathogenic	0.802
NPC1	O15118-1.2	T1130E	Pathogenic	0.821
NPC1	O15118-1.2	T1130F	Pathogenic	0.865
NPC1	O15118-1.2	T1130G	Pathogenic	0.909
NPC1	O15118-1.2	T1130H	Pathogenic	0.902
NPC1	O15118-1.2	T1130I	Pathogenic	0.802
NPC1	O15118-1.2	T1130K	Pathogenic	0.827
NPC1	O15118-1.2	T1130L	Pathogenic	0.808
NPC1	O15118-1.2	T1130M	Pathogenic	0.831
NPC1	O15118-1.2	T1130N	Pathogenic	0.745
NPC1	O15118-1.2	T1130P	Pathogenic	0.831
NPC1	O15118-1.2	T1130Q	Pathogenic	0.845
NPC1	O15118-1.2	T1130R	Pathogenic	0.838
NPC1	O15118-1.2	T1130S	Pathogenic	0.727
NPC1	O15118-1.2	T1130V	Pathogenic	0.749
NPC1	O15118-1.2	T1130W	Pathogenic	0.867
NPC1	O15118-1.2	T1130Y	Pathogenic	0.897
NPC1	O15118-1.2	I1131A	Pathogenic	0.792
NPC1	O15118-1.2	I1131C	Pathogenic	0.809
NPC1	O15118-1.2	I1131D	Pathogenic	0.833
NPC1	O15118-1.2	I1131E	Pathogenic	0.823
NPC1	O15118-1.2	I1131F	Pathogenic	0.762
NPC1	O15118-1.2	I1131G	Pathogenic	0.925
NPC1	O15118-1.2	I1131H	Pathogenic	0.851
NPC1	O15118-1.2	I1131K	Pathogenic	0.802
NPC1	O15118-1.2	I1131L	Pathogenic	0.574
NPC1	O15118-1.2	I1131M	Pathogenic	0.629
NPC1	O15118-1.2	I1131N	Pathogenic	0.836
NPC1	O15118-1.2	I1131P	Pathogenic	0.891
NPC1	O15118-1.2	I1131Q	Pathogenic	0.839
NPC1	O15118-1.2	I1131R	Pathogenic	0.813
NPC1	O15118-1.2	I1131S	Pathogenic	0.828
NPC1	O15118-1.2	I1131T	Pathogenic	0.762
NPC1	O15118-1.2	I1131V	Neutral	0.466
NPC1	O15118-1.2	I1131W	Pathogenic	0.913
NPC1	O15118-1.2	I1131Y	Pathogenic	0.788
NPC1	O15118-1.2	A1132C	Neutral	0.141
NPC1	O15118-1.2	A1132D	Neutral	0.242
NPC1	O15118-1.2	A1132E	Neutral	0.202
NPC1	O15118-1.2	A1132F	Neutral	0.267
NPC1	O15118-1.2	A1132G	Neutral	0.156
NPC1	O15118-1.2	A1132H	Neutral	0.336
NPC1	O15118-1.2	A1132I	Neutral	0.187
NPC1	O15118-1.2	A1132K	Neutral	0.208
NPC1	O15118-1.2	A1132L	Neutral	0.193
NPC1	O15118-1.2	A1132M	Neutral	0.218
NPC1	O15118-1.2	A1132N	Neutral	0.258
NPC1	O15118-1.2	A1132P	Neutral	0.212
NPC1	O15118-1.2	A1132Q	Neutral	0.23
NPC1	O15118-1.2	A1132R	Neutral	0.221
NPC1	O15118-1.2	A1132S	Neutral	0.103
NPC1	O15118-1.2	A1132T	Neutral	0.174
NPC1	O15118-1.2	A1132V	Neutral	0.145
NPC1	O15118-1.2	A1132W	Neutral	0.352
NPC1	O15118-1.2	A1132Y	Neutral	0.332
NPC1	O15118-1.2	M1133A	Pathogenic	0.828
NPC1	O15118-1.2	M1133C	Pathogenic	0.843
NPC1	O15118-1.2	M1133D	Pathogenic	0.863
NPC1	O15118-1.2	M1133E	Pathogenic	0.801
NPC1	O15118-1.2	M1133F	Pathogenic	0.737
NPC1	O15118-1.2	M1133G	Pathogenic	0.914
NPC1	O15118-1.2	M1133H	Pathogenic	0.831
NPC1	O15118-1.2	M1133I	Pathogenic	0.64
NPC1	O15118-1.2	M1133K	Pathogenic	0.704
NPC1	O15118-1.2	M1133L	Pathogenic	0.556
NPC1	O15118-1.2	M1133N	Pathogenic	0.815
NPC1	O15118-1.2	M1133P	Pathogenic	0.876
NPC1	O15118-1.2	M1133Q	Pathogenic	0.675
NPC1	O15118-1.2	M1133R	Pathogenic	0.719
NPC1	O15118-1.2	M1133S	Pathogenic	0.806
NPC1	O15118-1.2	M1133T	Pathogenic	0.802
NPC1	O15118-1.2	M1133V	Pathogenic	0.706
NPC1	O15118-1.2	M1133W	Pathogenic	0.808
NPC1	O15118-1.2	M1133Y	Pathogenic	0.825
NPC1	O15118-1.2	V1134A	Neutral	0.439
NPC1	O15118-1.2	V1134C	Pathogenic	0.563
NPC1	O15118-1.2	V1134D	Pathogenic	0.601
NPC1	O15118-1.2	V1134E	Pathogenic	0.502
NPC1	O15118-1.2	V1134F	Pathogenic	0.551
NPC1	O15118-1.2	V1134G	Pathogenic	0.716
NPC1	O15118-1.2	V1134H	Pathogenic	0.669
NPC1	O15118-1.2	V1134I	Neutral	0.196
NPC1	O15118-1.2	V1134K	Pathogenic	0.512
NPC1	O15118-1.2	V1134L	Neutral	0.354
NPC1	O15118-1.2	V1134M	Neutral	0.39
NPC1	O15118-1.2	V1134N	Pathogenic	0.607
NPC1	O15118-1.2	V1134P	Pathogenic	0.628
NPC1	O15118-1.2	V1134Q	Pathogenic	0.544
NPC1	O15118-1.2	V1134R	Pathogenic	0.624
NPC1	O15118-1.2	V1134S	Pathogenic	0.593
NPC1	O15118-1.2	V1134T	Neutral	0.397
NPC1	O15118-1.2	V1134W	Pathogenic	0.73
NPC1	O15118-1.2	V1134Y	Pathogenic	0.586
NPC1	O15118-1.2	L1135A	Neutral	0.282
NPC1	O15118-1.2	L1135C	Neutral	0.305
NPC1	O15118-1.2	L1135D	Neutral	0.431
NPC1	O15118-1.2	L1135E	Neutral	0.325
NPC1	O15118-1.2	L1135F	Neutral	0.238
NPC1	O15118-1.2	L1135G	Pathogenic	0.559
NPC1	O15118-1.2	L1135H	Neutral	0.371
NPC1	O15118-1.2	L1135I	Neutral	0.119
NPC1	O15118-1.2	L1135K	Neutral	0.221
NPC1	O15118-1.2	L1135M	Neutral	0.106
NPC1	O15118-1.2	L1135N	Neutral	0.345
NPC1	O15118-1.2	L1135P	Neutral	0.459
NPC1	O15118-1.2	L1135Q	Neutral	0.268
NPC1	O15118-1.2	L1135R	Neutral	0.234
NPC1	O15118-1.2	L1135S	Neutral	0.332
NPC1	O15118-1.2	L1135T	Neutral	0.248
NPC1	O15118-1.2	L1135V	Neutral	0.163
NPC1	O15118-1.2	L1135W	Neutral	0.407
NPC1	O15118-1.2	L1135Y	Neutral	0.277
NPC1	O15118-1.2	V1136A	Neutral	0.266
NPC1	O15118-1.2	V1136C	Neutral	0.373
NPC1	O15118-1.2	V1136D	Neutral	0.411
NPC1	O15118-1.2	V1136E	Neutral	0.318
NPC1	O15118-1.2	V1136F	Neutral	0.363
NPC1	O15118-1.2	V1136G	Pathogenic	0.539
NPC1	O15118-1.2	V1136H	Neutral	0.483
NPC1	O15118-1.2	V1136I	Neutral	0.102
NPC1	O15118-1.2	V1136K	Neutral	0.327
NPC1	O15118-1.2	V1136L	Neutral	0.202
NPC1	O15118-1.2	V1136M	Neutral	0.228
NPC1	O15118-1.2	V1136N	Neutral	0.417
NPC1	O15118-1.2	V1136P	Neutral	0.439
NPC1	O15118-1.2	V1136Q	Neutral	0.356
NPC1	O15118-1.2	V1136R	Neutral	0.435
NPC1	O15118-1.2	V1136S	Neutral	0.403
NPC1	O15118-1.2	V1136T	Neutral	0.234
NPC1	O15118-1.2	V1136W	Pathogenic	0.556
NPC1	O15118-1.2	V1136Y	Neutral	0.396
NPC1	O15118-1.2	N1137A	Pathogenic	0.698
NPC1	O15118-1.2	N1137C	Pathogenic	0.708
NPC1	O15118-1.2	N1137D	Neutral	0.445
NPC1	O15118-1.2	N1137E	Pathogenic	0.564
NPC1	O15118-1.2	N1137F	Pathogenic	0.688
NPC1	O15118-1.2	N1137G	Pathogenic	0.57
NPC1	O15118-1.2	N1137H	Neutral	0.425
NPC1	O15118-1.2	N1137I	Pathogenic	0.673
NPC1	O15118-1.2	N1137K	Pathogenic	0.574
NPC1	O15118-1.2	N1137L	Pathogenic	0.68
NPC1	O15118-1.2	N1137M	Pathogenic	0.628
NPC1	O15118-1.2	N1137P	Pathogenic	0.637
NPC1	O15118-1.2	N1137Q	Pathogenic	0.543
NPC1	O15118-1.2	N1137R	Pathogenic	0.592
NPC1	O15118-1.2	N1137S	Neutral	0.44
NPC1	O15118-1.2	N1137T	Neutral	0.481
NPC1	O15118-1.2	N1137V	Pathogenic	0.69
NPC1	O15118-1.2	N1137W	Pathogenic	0.767
NPC1	O15118-1.2	N1137Y	Pathogenic	0.672
NPC1	O15118-1.2	M1138A	Neutral	0.478
NPC1	O15118-1.2	M1138C	Pathogenic	0.505
NPC1	O15118-1.2	M1138D	Pathogenic	0.545
NPC1	O15118-1.2	M1138E	Neutral	0.433
NPC1	O15118-1.2	M1138F	Neutral	0.347
NPC1	O15118-1.2	M1138G	Pathogenic	0.667
NPC1	O15118-1.2	M1138H	Neutral	0.483
NPC1	O15118-1.2	M1138I	Neutral	0.252
NPC1	O15118-1.2	M1138K	Neutral	0.311
NPC1	O15118-1.2	M1138L	Neutral	0.192
NPC1	O15118-1.2	M1138N	Neutral	0.455
NPC1	O15118-1.2	M1138P	Pathogenic	0.573
NPC1	O15118-1.2	M1138Q	Neutral	0.282
NPC1	O15118-1.2	M1138R	Neutral	0.327
NPC1	O15118-1.2	M1138S	Neutral	0.441
NPC1	O15118-1.2	M1138T	Neutral	0.435
NPC1	O15118-1.2	M1138V	Neutral	0.313
NPC1	O15118-1.2	M1138W	Neutral	0.443
NPC1	O15118-1.2	M1138Y	Neutral	0.472
NPC1	O15118-1.2	F1139A	Neutral	0.328
NPC1	O15118-1.2	F1139C	Neutral	0.352
NPC1	O15118-1.2	F1139D	Neutral	0.303
NPC1	O15118-1.2	F1139E	Neutral	0.289
NPC1	O15118-1.2	F1139G	Neutral	0.421
NPC1	O15118-1.2	F1139H	Neutral	0.187
NPC1	O15118-1.2	F1139I	Neutral	0.206
NPC1	O15118-1.2	F1139K	Neutral	0.236
NPC1	O15118-1.2	F1139L	Neutral	0.202
NPC1	O15118-1.2	F1139M	Neutral	0.178
NPC1	O15118-1.2	F1139N	Neutral	0.308
NPC1	O15118-1.2	F1139P	Pathogenic	0.513
NPC1	O15118-1.2	F1139Q	Neutral	0.312
NPC1	O15118-1.2	F1139R	Neutral	0.25
NPC1	O15118-1.2	F1139S	Neutral	0.296
NPC1	O15118-1.2	F1139T	Neutral	0.291
NPC1	O15118-1.2	F1139V	Neutral	0.263
NPC1	O15118-1.2	F1139W	Neutral	0.144
NPC1	O15118-1.2	F1139Y	Neutral	0.057
NPC1	O15118-1.2	G1140A	Pathogenic	0.781
NPC1	O15118-1.2	G1140C	Pathogenic	0.911
NPC1	O15118-1.2	G1140D	Pathogenic	0.839
NPC1	O15118-1.2	G1140E	Pathogenic	0.899
NPC1	O15118-1.2	G1140F	Pathogenic	0.913
NPC1	O15118-1.2	G1140H	Pathogenic	0.918
NPC1	O15118-1.2	G1140I	Pathogenic	0.935
NPC1	O15118-1.2	G1140K	Pathogenic	0.903
NPC1	O15118-1.2	G1140L	Pathogenic	0.937
NPC1	O15118-1.2	G1140M	Pathogenic	0.922
NPC1	O15118-1.2	G1140N	Pathogenic	0.794
NPC1	O15118-1.2	G1140P	Pathogenic	0.886
NPC1	O15118-1.2	G1140Q	Pathogenic	0.914
NPC1	O15118-1.2	G1140R	Pathogenic	0.909
NPC1	O15118-1.2	G1140S	Pathogenic	0.802
NPC1	O15118-1.2	G1140T	Pathogenic	0.902
NPC1	O15118-1.2	G1140V	Pathogenic	0.914
NPC1	O15118-1.2	G1140W	Pathogenic	0.879
NPC1	O15118-1.2	G1140Y	Pathogenic	0.935
NPC1	O15118-1.2	V1141A	Neutral	0.199
NPC1	O15118-1.2	V1141C	Neutral	0.29
NPC1	O15118-1.2	V1141D	Neutral	0.323
NPC1	O15118-1.2	V1141E	Neutral	0.242
NPC1	O15118-1.2	V1141F	Neutral	0.28
NPC1	O15118-1.2	V1141G	Neutral	0.445
NPC1	O15118-1.2	V1141H	Neutral	0.391
NPC1	O15118-1.2	V1141I	Neutral	0.072
NPC1	O15118-1.2	V1141K	Neutral	0.25
NPC1	O15118-1.2	V1141L	Neutral	0.148
NPC1	O15118-1.2	V1141M	Neutral	0.169
NPC1	O15118-1.2	V1141N	Neutral	0.329
NPC1	O15118-1.2	V1141P	Neutral	0.349
NPC1	O15118-1.2	V1141Q	Neutral	0.275
NPC1	O15118-1.2	V1141R	Neutral	0.345
NPC1	O15118-1.2	V1141S	Neutral	0.316
NPC1	O15118-1.2	V1141T	Neutral	0.173
NPC1	O15118-1.2	V1141W	Neutral	0.461
NPC1	O15118-1.2	V1141Y	Neutral	0.31
NPC1	O15118-1.2	M1142A	Pathogenic	0.897
NPC1	O15118-1.2	M1142C	Pathogenic	0.906
NPC1	O15118-1.2	M1142D	Pathogenic	0.919
NPC1	O15118-1.2	M1142E	Pathogenic	0.879
NPC1	O15118-1.2	M1142F	Pathogenic	0.835
NPC1	O15118-1.2	M1142G	Pathogenic	0.95
NPC1	O15118-1.2	M1142H	Pathogenic	0.898
NPC1	O15118-1.2	M1142I	Pathogenic	0.762
NPC1	O15118-1.2	M1142K	Pathogenic	0.81
NPC1	O15118-1.2	M1142L	Pathogenic	0.692
NPC1	O15118-1.2	M1142N	Pathogenic	0.888
NPC1	O15118-1.2	M1142P	Pathogenic	0.927
NPC1	O15118-1.2	M1142Q	Pathogenic	0.789
NPC1	O15118-1.2	M1142R	Pathogenic	0.821
NPC1	O15118-1.2	M1142S	Pathogenic	0.882
NPC1	O15118-1.2	M1142T	Pathogenic	0.879
NPC1	O15118-1.2	M1142V	Pathogenic	0.812
NPC1	O15118-1.2	M1142W	Pathogenic	0.883
NPC1	O15118-1.2	M1142Y	Pathogenic	0.894
NPC1	O15118-1.2	W1143A	Pathogenic	0.753
NPC1	O15118-1.2	W1143C	Pathogenic	0.699
NPC1	O15118-1.2	W1143D	Pathogenic	0.731
NPC1	O15118-1.2	W1143E	Pathogenic	0.634
NPC1	O15118-1.2	W1143F	Neutral	0.414
NPC1	O15118-1.2	W1143G	Pathogenic	0.678
NPC1	O15118-1.2	W1143H	Pathogenic	0.59
NPC1	O15118-1.2	W1143I	Pathogenic	0.781
NPC1	O15118-1.2	W1143K	Pathogenic	0.568
NPC1	O15118-1.2	W1143L	Pathogenic	0.7
NPC1	O15118-1.2	W1143M	Pathogenic	0.576
NPC1	O15118-1.2	W1143N	Pathogenic	0.736
NPC1	O15118-1.2	W1143P	Pathogenic	0.818
NPC1	O15118-1.2	W1143Q	Pathogenic	0.567
NPC1	O15118-1.2	W1143R	Pathogenic	0.548
NPC1	O15118-1.2	W1143S	Pathogenic	0.724
NPC1	O15118-1.2	W1143T	Pathogenic	0.636
NPC1	O15118-1.2	W1143V	Pathogenic	0.767
NPC1	O15118-1.2	W1143Y	Neutral	0.261
NPC1	O15118-1.2	L1144A	Neutral	0.366
NPC1	O15118-1.2	L1144C	Neutral	0.392
NPC1	O15118-1.2	L1144D	Pathogenic	0.526
NPC1	O15118-1.2	L1144E	Neutral	0.414
NPC1	O15118-1.2	L1144F	Neutral	0.314
NPC1	O15118-1.2	L1144G	Pathogenic	0.65
NPC1	O15118-1.2	L1144H	Neutral	0.464
NPC1	O15118-1.2	L1144I	Neutral	0.165
NPC1	O15118-1.2	L1144K	Neutral	0.295
NPC1	O15118-1.2	L1144M	Neutral	0.149
NPC1	O15118-1.2	L1144N	Neutral	0.437
NPC1	O15118-1.2	L1144P	Pathogenic	0.555
NPC1	O15118-1.2	L1144Q	Neutral	0.349
NPC1	O15118-1.2	L1144R	Neutral	0.31
NPC1	O15118-1.2	L1144S	Neutral	0.422
NPC1	O15118-1.2	L1144T	Neutral	0.327
NPC1	O15118-1.2	L1144V	Neutral	0.223
NPC1	O15118-1.2	L1144W	Pathogenic	0.502
NPC1	O15118-1.2	L1144Y	Neutral	0.36
NPC1	O15118-1.2	W1145A	Pathogenic	0.96
NPC1	O15118-1.2	W1145C	Pathogenic	0.947
NPC1	O15118-1.2	W1145D	Pathogenic	0.955
NPC1	O15118-1.2	W1145E	Pathogenic	0.931
NPC1	O15118-1.2	W1145F	Pathogenic	0.846
NPC1	O15118-1.2	W1145G	Pathogenic	0.942
NPC1	O15118-1.2	W1145H	Pathogenic	0.918
NPC1	O15118-1.2	W1145I	Pathogenic	0.965
NPC1	O15118-1.2	W1145K	Pathogenic	0.911
NPC1	O15118-1.2	W1145L	Pathogenic	0.948
NPC1	O15118-1.2	W1145M	Pathogenic	0.914
NPC1	O15118-1.2	W1145N	Pathogenic	0.956
NPC1	O15118-1.2	W1145P	Pathogenic	0.972
NPC1	O15118-1.2	W1145Q	Pathogenic	0.911
NPC1	O15118-1.2	W1145R	Pathogenic	0.904
NPC1	O15118-1.2	W1145S	Pathogenic	0.953
NPC1	O15118-1.2	W1145T	Pathogenic	0.931
NPC1	O15118-1.2	W1145V	Pathogenic	0.962
NPC1	O15118-1.2	W1145Y	Pathogenic	0.733
NPC1	O15118-1.2	G1146A	Neutral	0.473
NPC1	O15118-1.2	G1146C	Pathogenic	0.719
NPC1	O15118-1.2	G1146D	Pathogenic	0.567
NPC1	O15118-1.2	G1146E	Pathogenic	0.691
NPC1	O15118-1.2	G1146F	Pathogenic	0.725
NPC1	O15118-1.2	G1146H	Pathogenic	0.737
NPC1	O15118-1.2	G1146I	Pathogenic	0.783
NPC1	O15118-1.2	G1146K	Pathogenic	0.7
NPC1	O15118-1.2	G1146L	Pathogenic	0.788
NPC1	O15118-1.2	G1146M	Pathogenic	0.748
NPC1	O15118-1.2	G1146N	Neutral	0.492
NPC1	O15118-1.2	G1146P	Pathogenic	0.66
NPC1	O15118-1.2	G1146Q	Pathogenic	0.726
NPC1	O15118-1.2	G1146R	Pathogenic	0.715
NPC1	O15118-1.2	G1146S	Pathogenic	0.504
NPC1	O15118-1.2	G1146T	Pathogenic	0.698
NPC1	O15118-1.2	G1146V	Pathogenic	0.726
NPC1	O15118-1.2	G1146W	Pathogenic	0.645
NPC1	O15118-1.2	G1146Y	Pathogenic	0.782
NPC1	O15118-1.2	I1147A	Pathogenic	0.805
NPC1	O15118-1.2	I1147C	Pathogenic	0.822
NPC1	O15118-1.2	I1147D	Pathogenic	0.844
NPC1	O15118-1.2	I1147E	Pathogenic	0.835
NPC1	O15118-1.2	I1147F	Pathogenic	0.777
NPC1	O15118-1.2	I1147G	Pathogenic	0.93
NPC1	O15118-1.2	I1147H	Pathogenic	0.861
NPC1	O15118-1.2	I1147K	Pathogenic	0.815
NPC1	O15118-1.2	I1147L	Pathogenic	0.594
NPC1	O15118-1.2	I1147M	Pathogenic	0.648
NPC1	O15118-1.2	I1147N	Pathogenic	0.847
NPC1	O15118-1.2	I1147P	Pathogenic	0.899
NPC1	O15118-1.2	I1147Q	Pathogenic	0.85
NPC1	O15118-1.2	I1147R	Pathogenic	0.826
NPC1	O15118-1.2	I1147S	Pathogenic	0.84
NPC1	O15118-1.2	I1147T	Pathogenic	0.776
NPC1	O15118-1.2	I1147V	Neutral	0.487
NPC1	O15118-1.2	I1147W	Pathogenic	0.919
NPC1	O15118-1.2	I1147Y	Pathogenic	0.801
NPC1	O15118-1.2	S1148A	Neutral	0.153
NPC1	O15118-1.2	S1148C	Neutral	0.246
NPC1	O15118-1.2	S1148D	Neutral	0.201
NPC1	O15118-1.2	S1148E	Neutral	0.226
NPC1	O15118-1.2	S1148F	Neutral	0.33
NPC1	O15118-1.2	S1148G	Neutral	0.248
NPC1	O15118-1.2	S1148H	Neutral	0.344
NPC1	O15118-1.2	S1148I	Neutral	0.314
NPC1	O15118-1.2	S1148K	Neutral	0.233
NPC1	O15118-1.2	S1148L	Neutral	0.322
NPC1	O15118-1.2	S1148M	Neutral	0.274
NPC1	O15118-1.2	S1148N	Neutral	0.157
NPC1	O15118-1.2	S1148P	Neutral	0.267
NPC1	O15118-1.2	S1148Q	Neutral	0.257
NPC1	O15118-1.2	S1148R	Neutral	0.325
NPC1	O15118-1.2	S1148T	Neutral	0.167
NPC1	O15118-1.2	S1148V	Neutral	0.332
NPC1	O15118-1.2	S1148W	Neutral	0.424
NPC1	O15118-1.2	S1148Y	Neutral	0.402
NPC1	O15118-1.2	L1149A	Pathogenic	0.674
NPC1	O15118-1.2	L1149C	Pathogenic	0.698
NPC1	O15118-1.2	L1149D	Pathogenic	0.799
NPC1	O15118-1.2	L1149E	Pathogenic	0.717
NPC1	O15118-1.2	L1149F	Pathogenic	0.622
NPC1	O15118-1.2	L1149G	Pathogenic	0.869
NPC1	O15118-1.2	L1149H	Pathogenic	0.756
NPC1	O15118-1.2	L1149I	Neutral	0.414
NPC1	O15118-1.2	L1149K	Pathogenic	0.599
NPC1	O15118-1.2	L1149M	Neutral	0.385
NPC1	O15118-1.2	L1149N	Pathogenic	0.735
NPC1	O15118-1.2	L1149P	Pathogenic	0.817
NPC1	O15118-1.2	L1149Q	Pathogenic	0.658
NPC1	O15118-1.2	L1149R	Pathogenic	0.617
NPC1	O15118-1.2	L1149S	Pathogenic	0.723
NPC1	O15118-1.2	L1149T	Pathogenic	0.635
NPC1	O15118-1.2	L1149V	Pathogenic	0.507
NPC1	O15118-1.2	L1149W	Pathogenic	0.783
NPC1	O15118-1.2	L1149Y	Pathogenic	0.668
NPC1	O15118-1.2	N1150A	Pathogenic	0.896
NPC1	O15118-1.2	N1150C	Pathogenic	0.9
NPC1	O15118-1.2	N1150D	Pathogenic	0.749
NPC1	O15118-1.2	N1150E	Pathogenic	0.828
NPC1	O15118-1.2	N1150F	Pathogenic	0.891
NPC1	O15118-1.2	N1150G	Pathogenic	0.831
NPC1	O15118-1.2	N1150H	Pathogenic	0.732
NPC1	O15118-1.2	N1150I	Pathogenic	0.884
NPC1	O15118-1.2	N1150K	Pathogenic	0.833
NPC1	O15118-1.2	N1150L	Pathogenic	0.887
NPC1	O15118-1.2	N1150M	Pathogenic	0.862
NPC1	O15118-1.2	N1150P	Pathogenic	0.867
NPC1	O15118-1.2	N1150Q	Pathogenic	0.815
NPC1	O15118-1.2	N1150R	Pathogenic	0.843
NPC1	O15118-1.2	N1150S	Pathogenic	0.744
NPC1	O15118-1.2	N1150T	Pathogenic	0.775
NPC1	O15118-1.2	N1150V	Pathogenic	0.892
NPC1	O15118-1.2	N1150W	Pathogenic	0.924
NPC1	O15118-1.2	N1150Y	Pathogenic	0.884
NPC1	O15118-1.2	A1151C	Pathogenic	0.785
NPC1	O15118-1.2	A1151D	Pathogenic	0.877
NPC1	O15118-1.2	A1151E	Pathogenic	0.85
NPC1	O15118-1.2	A1151F	Pathogenic	0.891
NPC1	O15118-1.2	A1151G	Pathogenic	0.805
NPC1	O15118-1.2	A1151H	Pathogenic	0.919
NPC1	O15118-1.2	A1151I	Pathogenic	0.838
NPC1	O15118-1.2	A1151K	Pathogenic	0.855
NPC1	O15118-1.2	A1151L	Pathogenic	0.842
NPC1	O15118-1.2	A1151M	Pathogenic	0.862
NPC1	O15118-1.2	A1151N	Pathogenic	0.886
NPC1	O15118-1.2	A1151P	Pathogenic	0.858
NPC1	O15118-1.2	A1151Q	Pathogenic	0.87
NPC1	O15118-1.2	A1151R	Pathogenic	0.864
NPC1	O15118-1.2	A1151S	Pathogenic	0.72
NPC1	O15118-1.2	A1151T	Pathogenic	0.824
NPC1	O15118-1.2	A1151V	Pathogenic	0.792
NPC1	O15118-1.2	A1151W	Pathogenic	0.924
NPC1	O15118-1.2	A1151Y	Pathogenic	0.918
NPC1	O15118-1.2	V1152A	Pathogenic	0.633
NPC1	O15118-1.2	V1152C	Pathogenic	0.738
NPC1	O15118-1.2	V1152D	Pathogenic	0.768
NPC1	O15118-1.2	V1152E	Pathogenic	0.689
NPC1	O15118-1.2	V1152F	Pathogenic	0.73
NPC1	O15118-1.2	V1152G	Pathogenic	0.847
NPC1	O15118-1.2	V1152H	Pathogenic	0.816
NPC1	O15118-1.2	V1152I	Neutral	0.349
NPC1	O15118-1.2	V1152K	Pathogenic	0.697
NPC1	O15118-1.2	V1152L	Pathogenic	0.546
NPC1	O15118-1.2	V1152M	Pathogenic	0.584
NPC1	O15118-1.2	V1152N	Pathogenic	0.773
NPC1	O15118-1.2	V1152P	Pathogenic	0.788
NPC1	O15118-1.2	V1152Q	Pathogenic	0.724
NPC1	O15118-1.2	V1152R	Pathogenic	0.785
NPC1	O15118-1.2	V1152S	Pathogenic	0.762
NPC1	O15118-1.2	V1152T	Pathogenic	0.591
NPC1	O15118-1.2	V1152W	Pathogenic	0.856
NPC1	O15118-1.2	V1152Y	Pathogenic	0.757
NPC1	O15118-1.2	S1153A	Pathogenic	0.617
NPC1	O15118-1.2	S1153C	Pathogenic	0.744
NPC1	O15118-1.2	S1153D	Pathogenic	0.692
NPC1	O15118-1.2	S1153E	Pathogenic	0.723
NPC1	O15118-1.2	S1153F	Pathogenic	0.815
NPC1	O15118-1.2	S1153G	Pathogenic	0.747
NPC1	O15118-1.2	S1153H	Pathogenic	0.824
NPC1	O15118-1.2	S1153I	Pathogenic	0.804
NPC1	O15118-1.2	S1153K	Pathogenic	0.731
NPC1	O15118-1.2	S1153L	Pathogenic	0.809
NPC1	O15118-1.2	S1153M	Pathogenic	0.771
NPC1	O15118-1.2	S1153N	Pathogenic	0.624
NPC1	O15118-1.2	S1153P	Pathogenic	0.765
NPC1	O15118-1.2	S1153Q	Pathogenic	0.756
NPC1	O15118-1.2	S1153R	Pathogenic	0.812
NPC1	O15118-1.2	S1153T	Pathogenic	0.641
NPC1	O15118-1.2	S1153V	Pathogenic	0.816
NPC1	O15118-1.2	S1153W	Pathogenic	0.868
NPC1	O15118-1.2	S1153Y	Pathogenic	0.857
NPC1	O15118-1.2	L1154A	Pathogenic	0.773
NPC1	O15118-1.2	L1154C	Pathogenic	0.791
NPC1	O15118-1.2	L1154D	Pathogenic	0.867
NPC1	O15118-1.2	L1154E	Pathogenic	0.807
NPC1	O15118-1.2	L1154F	Pathogenic	0.73
NPC1	O15118-1.2	L1154G	Pathogenic	0.916
NPC1	O15118-1.2	L1154H	Pathogenic	0.836
NPC1	O15118-1.2	L1154I	Pathogenic	0.538
NPC1	O15118-1.2	L1154K	Pathogenic	0.711
NPC1	O15118-1.2	L1154M	Pathogenic	0.507
NPC1	O15118-1.2	L1154N	Pathogenic	0.82
NPC1	O15118-1.2	L1154P	Pathogenic	0.88
NPC1	O15118-1.2	L1154Q	Pathogenic	0.76
NPC1	O15118-1.2	L1154R	Pathogenic	0.726
NPC1	O15118-1.2	L1154S	Pathogenic	0.811
NPC1	O15118-1.2	L1154T	Pathogenic	0.741
NPC1	O15118-1.2	L1154V	Pathogenic	0.628
NPC1	O15118-1.2	L1154W	Pathogenic	0.856
NPC1	O15118-1.2	L1154Y	Pathogenic	0.768
NPC1	O15118-1.2	V1155A	Pathogenic	0.688
NPC1	O15118-1.2	V1155C	Pathogenic	0.783
NPC1	O15118-1.2	V1155D	Pathogenic	0.809
NPC1	O15118-1.2	V1155E	Pathogenic	0.739
NPC1	O15118-1.2	V1155F	Pathogenic	0.775
NPC1	O15118-1.2	V1155G	Pathogenic	0.876
NPC1	O15118-1.2	V1155H	Pathogenic	0.85
NPC1	O15118-1.2	V1155I	Neutral	0.407
NPC1	O15118-1.2	V1155K	Pathogenic	0.747
NPC1	O15118-1.2	V1155L	Pathogenic	0.606
NPC1	O15118-1.2	V1155M	Pathogenic	0.642
NPC1	O15118-1.2	V1155N	Pathogenic	0.813
NPC1	O15118-1.2	V1155P	Pathogenic	0.826
NPC1	O15118-1.2	V1155Q	Pathogenic	0.77
NPC1	O15118-1.2	V1155R	Pathogenic	0.824
NPC1	O15118-1.2	V1155S	Pathogenic	0.804
NPC1	O15118-1.2	V1155T	Pathogenic	0.649
NPC1	O15118-1.2	V1155W	Pathogenic	0.884
NPC1	O15118-1.2	V1155Y	Pathogenic	0.799
NPC1	O15118-1.2	N1156A	Pathogenic	0.896
NPC1	O15118-1.2	N1156C	Pathogenic	0.9
NPC1	O15118-1.2	N1156D	Pathogenic	0.749
NPC1	O15118-1.2	N1156E	Pathogenic	0.828
NPC1	O15118-1.2	N1156F	Pathogenic	0.891
NPC1	O15118-1.2	N1156G	Pathogenic	0.831
NPC1	O15118-1.2	N1156H	Pathogenic	0.732
NPC1	O15118-1.2	N1156I	Pathogenic	0.884
NPC1	O15118-1.2	N1156K	Pathogenic	0.833
NPC1	O15118-1.2	N1156L	Pathogenic	0.887
NPC1	O15118-1.2	N1156M	Pathogenic	0.862
NPC1	O15118-1.2	N1156P	Pathogenic	0.867
NPC1	O15118-1.2	N1156Q	Pathogenic	0.815
NPC1	O15118-1.2	N1156R	Pathogenic	0.843
NPC1	O15118-1.2	N1156S	Pathogenic	0.744
NPC1	O15118-1.2	N1156T	Pathogenic	0.775
NPC1	O15118-1.2	N1156V	Pathogenic	0.892
NPC1	O15118-1.2	N1156W	Pathogenic	0.924
NPC1	O15118-1.2	N1156Y	Pathogenic	0.884
NPC1	O15118-1.2	L1157A	Pathogenic	0.808
NPC1	O15118-1.2	L1157C	Pathogenic	0.825
NPC1	O15118-1.2	L1157D	Pathogenic	0.89
NPC1	O15118-1.2	L1157E	Pathogenic	0.838
NPC1	O15118-1.2	L1157F	Pathogenic	0.77
NPC1	O15118-1.2	L1157G	Pathogenic	0.931
NPC1	O15118-1.2	L1157H	Pathogenic	0.863
NPC1	O15118-1.2	L1157I	Pathogenic	0.59
NPC1	O15118-1.2	L1157K	Pathogenic	0.753
NPC1	O15118-1.2	L1157M	Pathogenic	0.56
NPC1	O15118-1.2	L1157N	Pathogenic	0.85
NPC1	O15118-1.2	L1157P	Pathogenic	0.901
NPC1	O15118-1.2	L1157Q	Pathogenic	0.796
NPC1	O15118-1.2	L1157R	Pathogenic	0.766
NPC1	O15118-1.2	L1157S	Pathogenic	0.842
NPC1	O15118-1.2	L1157T	Pathogenic	0.78
NPC1	O15118-1.2	L1157V	Pathogenic	0.677
NPC1	O15118-1.2	L1157W	Pathogenic	0.88
NPC1	O15118-1.2	L1157Y	Pathogenic	0.804
NPC1	O15118-1.2	V1158A	Pathogenic	0.748
NPC1	O15118-1.2	V1158C	Pathogenic	0.829
NPC1	O15118-1.2	V1158D	Pathogenic	0.851
NPC1	O15118-1.2	V1158E	Pathogenic	0.792
NPC1	O15118-1.2	V1158F	Pathogenic	0.823
NPC1	O15118-1.2	V1158G	Pathogenic	0.905
NPC1	O15118-1.2	V1158H	Pathogenic	0.884
NPC1	O15118-1.2	V1158I	Neutral	0.48
NPC1	O15118-1.2	V1158K	Pathogenic	0.799
NPC1	O15118-1.2	V1158L	Pathogenic	0.674
NPC1	O15118-1.2	V1158M	Pathogenic	0.707
NPC1	O15118-1.2	V1158N	Pathogenic	0.854
NPC1	O15118-1.2	V1158P	Pathogenic	0.865
NPC1	O15118-1.2	V1158Q	Pathogenic	0.819
NPC1	O15118-1.2	V1158R	Pathogenic	0.863
NPC1	O15118-1.2	V1158S	Pathogenic	0.846
NPC1	O15118-1.2	V1158T	Pathogenic	0.713
NPC1	O15118-1.2	V1158W	Pathogenic	0.911
NPC1	O15118-1.2	V1158Y	Pathogenic	0.843
NPC1	O15118-1.2	M1159A	Pathogenic	0.828
NPC1	O15118-1.2	M1159C	Pathogenic	0.843
NPC1	O15118-1.2	M1159D	Pathogenic	0.863
NPC1	O15118-1.2	M1159E	Pathogenic	0.8
NPC1	O15118-1.2	M1159F	Pathogenic	0.736
NPC1	O15118-1.2	M1159G	Pathogenic	0.913
NPC1	O15118-1.2	M1159H	Pathogenic	0.83
NPC1	O15118-1.2	M1159I	Pathogenic	0.638
NPC1	O15118-1.2	M1159K	Pathogenic	0.702
NPC1	O15118-1.2	M1159L	Pathogenic	0.554
NPC1	O15118-1.2	M1159N	Pathogenic	0.814
NPC1	O15118-1.2	M1159P	Pathogenic	0.876
NPC1	O15118-1.2	M1159Q	Pathogenic	0.673
NPC1	O15118-1.2	M1159R	Pathogenic	0.718
NPC1	O15118-1.2	M1159S	Pathogenic	0.805
NPC1	O15118-1.2	M1159T	Pathogenic	0.801
NPC1	O15118-1.2	M1159V	Pathogenic	0.704
NPC1	O15118-1.2	M1159W	Pathogenic	0.807
NPC1	O15118-1.2	M1159Y	Pathogenic	0.824
NPC1	O15118-1.2	S1160A	Neutral	0.241
NPC1	O15118-1.2	S1160C	Neutral	0.365
NPC1	O15118-1.2	S1160D	Neutral	0.307
NPC1	O15118-1.2	S1160E	Neutral	0.34
NPC1	O15118-1.2	S1160F	Neutral	0.465
NPC1	O15118-1.2	S1160G	Neutral	0.368
NPC1	O15118-1.2	S1160H	Neutral	0.48
NPC1	O15118-1.2	S1160I	Neutral	0.447
NPC1	O15118-1.2	S1160K	Neutral	0.349
NPC1	O15118-1.2	S1160L	Neutral	0.456
NPC1	O15118-1.2	S1160M	Neutral	0.399
NPC1	O15118-1.2	S1160N	Neutral	0.247
NPC1	O15118-1.2	S1160P	Neutral	0.391
NPC1	O15118-1.2	S1160Q	Neutral	0.379
NPC1	O15118-1.2	S1160R	Neutral	0.459
NPC1	O15118-1.2	S1160T	Neutral	0.261
NPC1	O15118-1.2	S1160V	Neutral	0.467
NPC1	O15118-1.2	S1160W	Pathogenic	0.565
NPC1	O15118-1.2	S1160Y	Pathogenic	0.543
NPC1	O15118-1.2	C1161A	Neutral	0.317
NPC1	O15118-1.2	C1161D	Neutral	0.486
NPC1	O15118-1.2	C1161E	Pathogenic	0.619
NPC1	O15118-1.2	C1161F	Pathogenic	0.535
NPC1	O15118-1.2	C1161G	Pathogenic	0.599
NPC1	O15118-1.2	C1161H	Pathogenic	0.601
NPC1	O15118-1.2	C1161I	Neutral	0.421
NPC1	O15118-1.2	C1161K	Pathogenic	0.534
NPC1	O15118-1.2	C1161L	Neutral	0.43
NPC1	O15118-1.2	C1161M	Neutral	0.468
NPC1	O15118-1.2	C1161N	Pathogenic	0.508
NPC1	O15118-1.2	C1161P	Pathogenic	0.607
NPC1	O15118-1.2	C1161Q	Pathogenic	0.566
NPC1	O15118-1.2	C1161R	Pathogenic	0.553
NPC1	O15118-1.2	C1161S	Neutral	0.369
NPC1	O15118-1.2	C1161T	Neutral	0.384
NPC1	O15118-1.2	C1161V	Neutral	0.441
NPC1	O15118-1.2	C1161W	Pathogenic	0.539
NPC1	O15118-1.2	C1161Y	Pathogenic	0.607
NPC1	O15118-1.2	G1162A	Pathogenic	0.754
NPC1	O15118-1.2	G1162C	Pathogenic	0.897
NPC1	O15118-1.2	G1162D	Pathogenic	0.817
NPC1	O15118-1.2	G1162E	Pathogenic	0.885
NPC1	O15118-1.2	G1162F	Pathogenic	0.9
NPC1	O15118-1.2	G1162H	Pathogenic	0.905
NPC1	O15118-1.2	G1162I	Pathogenic	0.925
NPC1	O15118-1.2	G1162K	Pathogenic	0.889
NPC1	O15118-1.2	G1162L	Pathogenic	0.927
NPC1	O15118-1.2	G1162M	Pathogenic	0.91
NPC1	O15118-1.2	G1162N	Pathogenic	0.768
NPC1	O15118-1.2	G1162P	Pathogenic	0.869
NPC1	O15118-1.2	G1162Q	Pathogenic	0.901
NPC1	O15118-1.2	G1162R	Pathogenic	0.896
NPC1	O15118-1.2	G1162S	Pathogenic	0.777
NPC1	O15118-1.2	G1162T	Pathogenic	0.888
NPC1	O15118-1.2	G1162V	Pathogenic	0.901
NPC1	O15118-1.2	G1162W	Pathogenic	0.861
NPC1	O15118-1.2	G1162Y	Pathogenic	0.925
NPC1	O15118-1.2	I1163A	Pathogenic	0.763
NPC1	O15118-1.2	I1163C	Pathogenic	0.782
NPC1	O15118-1.2	I1163D	Pathogenic	0.808
NPC1	O15118-1.2	I1163E	Pathogenic	0.797
NPC1	O15118-1.2	I1163F	Pathogenic	0.73
NPC1	O15118-1.2	I1163G	Pathogenic	0.912
NPC1	O15118-1.2	I1163H	Pathogenic	0.828
NPC1	O15118-1.2	I1163K	Pathogenic	0.774
NPC1	O15118-1.2	I1163L	Pathogenic	0.532
NPC1	O15118-1.2	I1163M	Pathogenic	0.588
NPC1	O15118-1.2	I1163N	Pathogenic	0.812
NPC1	O15118-1.2	I1163P	Pathogenic	0.874
NPC1	O15118-1.2	I1163Q	Pathogenic	0.814
NPC1	O15118-1.2	I1163R	Pathogenic	0.786
NPC1	O15118-1.2	I1163S	Pathogenic	0.802
NPC1	O15118-1.2	I1163T	Pathogenic	0.73
NPC1	O15118-1.2	I1163V	Neutral	0.425
NPC1	O15118-1.2	I1163W	Pathogenic	0.898
NPC1	O15118-1.2	I1163Y	Pathogenic	0.758
NPC1	O15118-1.2	S1164A	Neutral	0.335
NPC1	O15118-1.2	S1164C	Neutral	0.477
NPC1	O15118-1.2	S1164D	Neutral	0.412
NPC1	O15118-1.2	S1164E	Neutral	0.45
NPC1	O15118-1.2	S1164F	Pathogenic	0.579
NPC1	O15118-1.2	S1164G	Neutral	0.48
NPC1	O15118-1.2	S1164H	Pathogenic	0.594
NPC1	O15118-1.2	S1164I	Pathogenic	0.562
NPC1	O15118-1.2	S1164K	Neutral	0.46
NPC1	O15118-1.2	S1164L	Pathogenic	0.57
NPC1	O15118-1.2	S1164M	Pathogenic	0.513
NPC1	O15118-1.2	S1164N	Neutral	0.342
NPC1	O15118-1.2	S1164P	Pathogenic	0.504
NPC1	O15118-1.2	S1164Q	Neutral	0.492
NPC1	O15118-1.2	S1164R	Pathogenic	0.574
NPC1	O15118-1.2	S1164T	Neutral	0.358
NPC1	O15118-1.2	S1164V	Pathogenic	0.581
NPC1	O15118-1.2	S1164W	Pathogenic	0.673
NPC1	O15118-1.2	S1164Y	Pathogenic	0.653
NPC1	O15118-1.2	V1165A	Pathogenic	0.703
NPC1	O15118-1.2	V1165C	Pathogenic	0.795
NPC1	O15118-1.2	V1165D	Pathogenic	0.82
NPC1	O15118-1.2	V1165E	Pathogenic	0.753
NPC1	O15118-1.2	V1165F	Pathogenic	0.788
NPC1	O15118-1.2	V1165G	Pathogenic	0.884
NPC1	O15118-1.2	V1165H	Pathogenic	0.859
NPC1	O15118-1.2	V1165I	Neutral	0.424
NPC1	O15118-1.2	V1165K	Pathogenic	0.76
NPC1	O15118-1.2	V1165L	Pathogenic	0.623
NPC1	O15118-1.2	V1165M	Pathogenic	0.659
NPC1	O15118-1.2	V1165N	Pathogenic	0.824
NPC1	O15118-1.2	V1165P	Pathogenic	0.836
NPC1	O15118-1.2	V1165Q	Pathogenic	0.783
NPC1	O15118-1.2	V1165R	Pathogenic	0.834
NPC1	O15118-1.2	V1165S	Pathogenic	0.815
NPC1	O15118-1.2	V1165T	Pathogenic	0.665
NPC1	O15118-1.2	V1165W	Pathogenic	0.891
NPC1	O15118-1.2	V1165Y	Pathogenic	0.81
NPC1	O15118-1.2	E1166A	Pathogenic	0.834
NPC1	O15118-1.2	E1166C	Pathogenic	0.919
NPC1	O15118-1.2	E1166D	Pathogenic	0.641
NPC1	O15118-1.2	E1166F	Pathogenic	0.858
NPC1	O15118-1.2	E1166G	Pathogenic	0.902
NPC1	O15118-1.2	E1166H	Pathogenic	0.748
NPC1	O15118-1.2	E1166I	Pathogenic	0.849
NPC1	O15118-1.2	E1166K	Pathogenic	0.72
NPC1	O15118-1.2	E1166L	Pathogenic	0.853
NPC1	O15118-1.2	E1166M	Pathogenic	0.822
NPC1	O15118-1.2	E1166N	Pathogenic	0.795
NPC1	O15118-1.2	E1166P	Pathogenic	0.792
NPC1	O15118-1.2	E1166Q	Pathogenic	0.6
NPC1	O15118-1.2	E1166R	Pathogenic	0.802
NPC1	O15118-1.2	E1166S	Pathogenic	0.787
NPC1	O15118-1.2	E1166T	Pathogenic	0.814
NPC1	O15118-1.2	E1166V	Pathogenic	0.813
NPC1	O15118-1.2	E1166W	Pathogenic	0.86
NPC1	O15118-1.2	E1166Y	Pathogenic	0.848
NPC1	O15118-1.2	F1167A	Pathogenic	0.856
NPC1	O15118-1.2	F1167C	Pathogenic	0.869
NPC1	O15118-1.2	F1167D	Pathogenic	0.841
NPC1	O15118-1.2	F1167E	Pathogenic	0.832
NPC1	O15118-1.2	F1167G	Pathogenic	0.899
NPC1	O15118-1.2	F1167H	Pathogenic	0.737
NPC1	O15118-1.2	F1167I	Pathogenic	0.761
NPC1	O15118-1.2	F1167K	Pathogenic	0.791
NPC1	O15118-1.2	F1167L	Pathogenic	0.756
NPC1	O15118-1.2	F1167M	Pathogenic	0.726
NPC1	O15118-1.2	F1167N	Pathogenic	0.845
NPC1	O15118-1.2	F1167P	Pathogenic	0.928
NPC1	O15118-1.2	F1167Q	Pathogenic	0.847
NPC1	O15118-1.2	F1167R	Pathogenic	0.802
NPC1	O15118-1.2	F1167S	Pathogenic	0.837
NPC1	O15118-1.2	F1167T	Pathogenic	0.833
NPC1	O15118-1.2	F1167V	Pathogenic	0.813
NPC1	O15118-1.2	F1167W	Pathogenic	0.673
NPC1	O15118-1.2	F1167Y	Neutral	0.425
NPC1	O15118-1.2	C1168A	Pathogenic	0.879
NPC1	O15118-1.2	C1168D	Pathogenic	0.937
NPC1	O15118-1.2	C1168E	Pathogenic	0.962
NPC1	O15118-1.2	C1168F	Pathogenic	0.948
NPC1	O15118-1.2	C1168G	Pathogenic	0.959
NPC1	O15118-1.2	C1168H	Pathogenic	0.959
NPC1	O15118-1.2	C1168I	Pathogenic	0.92
NPC1	O15118-1.2	C1168K	Pathogenic	0.947
NPC1	O15118-1.2	C1168L	Pathogenic	0.922
NPC1	O15118-1.2	C1168M	Pathogenic	0.933
NPC1	O15118-1.2	C1168N	Pathogenic	0.942
NPC1	O15118-1.2	C1168P	Pathogenic	0.96
NPC1	O15118-1.2	C1168Q	Pathogenic	0.954
NPC1	O15118-1.2	C1168R	Pathogenic	0.951
NPC1	O15118-1.2	C1168S	Pathogenic	0.902
NPC1	O15118-1.2	C1168T	Pathogenic	0.907
NPC1	O15118-1.2	C1168V	Pathogenic	0.925
NPC1	O15118-1.2	C1168W	Pathogenic	0.948
NPC1	O15118-1.2	C1168Y	Pathogenic	0.96
NPC1	O15118-1.2	S1169A	Pathogenic	0.815
NPC1	O15118-1.2	S1169C	Pathogenic	0.888
NPC1	O15118-1.2	S1169D	Pathogenic	0.859
NPC1	O15118-1.2	S1169E	Pathogenic	0.877
NPC1	O15118-1.2	S1169F	Pathogenic	0.923
NPC1	O15118-1.2	S1169G	Pathogenic	0.889
NPC1	O15118-1.2	S1169H	Pathogenic	0.927
NPC1	O15118-1.2	S1169I	Pathogenic	0.918
NPC1	O15118-1.2	S1169K	Pathogenic	0.881
NPC1	O15118-1.2	S1169L	Pathogenic	0.92
NPC1	O15118-1.2	S1169M	Pathogenic	0.902
NPC1	O15118-1.2	S1169N	Pathogenic	0.819
NPC1	O15118-1.2	S1169P	Pathogenic	0.899
NPC1	O15118-1.2	S1169Q	Pathogenic	0.894
NPC1	O15118-1.2	S1169R	Pathogenic	0.921
NPC1	O15118-1.2	S1169T	Pathogenic	0.829
NPC1	O15118-1.2	S1169V	Pathogenic	0.924
NPC1	O15118-1.2	S1169W	Pathogenic	0.947
NPC1	O15118-1.2	S1169Y	Pathogenic	0.942
NPC1	O15118-1.2	H1170A	Pathogenic	0.982
NPC1	O15118-1.2	H1170C	Pathogenic	0.983
NPC1	O15118-1.2	H1170D	Pathogenic	0.963
NPC1	O15118-1.2	H1170E	Pathogenic	0.943
NPC1	O15118-1.2	H1170F	Pathogenic	0.95
NPC1	O15118-1.2	H1170G	Pathogenic	0.985
NPC1	O15118-1.2	H1170I	Pathogenic	0.974
NPC1	O15118-1.2	H1170K	Pathogenic	0.958
NPC1	O15118-1.2	H1170L	Pathogenic	0.975
NPC1	O15118-1.2	H1170M	Pathogenic	0.969
NPC1	O15118-1.2	H1170N	Pathogenic	0.924
NPC1	O15118-1.2	H1170P	Pathogenic	0.977
NPC1	O15118-1.2	H1170Q	Pathogenic	0.948
NPC1	O15118-1.2	H1170R	Pathogenic	0.943
NPC1	O15118-1.2	H1170S	Pathogenic	0.973
NPC1	O15118-1.2	H1170T	Pathogenic	0.98
NPC1	O15118-1.2	H1170V	Pathogenic	0.98
NPC1	O15118-1.2	H1170W	Pathogenic	0.966
NPC1	O15118-1.2	H1170Y	Pathogenic	0.89
NPC1	O15118-1.2	I1171A	Pathogenic	0.585
NPC1	O15118-1.2	I1171C	Pathogenic	0.611
NPC1	O15118-1.2	I1171D	Pathogenic	0.649
NPC1	O15118-1.2	I1171E	Pathogenic	0.634
NPC1	O15118-1.2	I1171F	Pathogenic	0.543
NPC1	O15118-1.2	I1171G	Pathogenic	0.82
NPC1	O15118-1.2	I1171H	Pathogenic	0.679
NPC1	O15118-1.2	I1171K	Pathogenic	0.6
NPC1	O15118-1.2	I1171L	Neutral	0.333
NPC1	O15118-1.2	I1171M	Neutral	0.386
NPC1	O15118-1.2	I1171N	Pathogenic	0.654
NPC1	O15118-1.2	I1171P	Pathogenic	0.753
NPC1	O15118-1.2	I1171Q	Pathogenic	0.658
NPC1	O15118-1.2	I1171R	Pathogenic	0.618
NPC1	O15118-1.2	I1171S	Pathogenic	0.641
NPC1	O15118-1.2	I1171T	Pathogenic	0.542
NPC1	O15118-1.2	I1171V	Neutral	0.245
NPC1	O15118-1.2	I1171W	Pathogenic	0.795
NPC1	O15118-1.2	I1171Y	Pathogenic	0.579
NPC1	O15118-1.2	T1172A	Pathogenic	0.681
NPC1	O15118-1.2	T1172C	Pathogenic	0.692
NPC1	O15118-1.2	T1172D	Pathogenic	0.663
NPC1	O15118-1.2	T1172E	Pathogenic	0.691
NPC1	O15118-1.2	T1172F	Pathogenic	0.757
NPC1	O15118-1.2	T1172G	Pathogenic	0.829
NPC1	O15118-1.2	T1172H	Pathogenic	0.818
NPC1	O15118-1.2	T1172I	Pathogenic	0.664
NPC1	O15118-1.2	T1172K	Pathogenic	0.7
NPC1	O15118-1.2	T1172L	Pathogenic	0.671
NPC1	O15118-1.2	T1172M	Pathogenic	0.705
NPC1	O15118-1.2	T1172N	Pathogenic	0.587
NPC1	O15118-1.2	T1172P	Pathogenic	0.705
NPC1	O15118-1.2	T1172Q	Pathogenic	0.726
NPC1	O15118-1.2	T1172R	Pathogenic	0.715
NPC1	O15118-1.2	T1172S	Pathogenic	0.564
NPC1	O15118-1.2	T1172V	Pathogenic	0.592
NPC1	O15118-1.2	T1172W	Pathogenic	0.76
NPC1	O15118-1.2	T1172Y	Pathogenic	0.81
NPC1	O15118-1.2	R1173A	Pathogenic	0.882
NPC1	O15118-1.2	R1173C	Pathogenic	0.92
NPC1	O15118-1.2	R1173D	Pathogenic	0.932
NPC1	O15118-1.2	R1173E	Pathogenic	0.844
NPC1	O15118-1.2	R1173F	Pathogenic	0.868
NPC1	O15118-1.2	R1173G	Pathogenic	0.932
NPC1	O15118-1.2	R1173H	Pathogenic	0.799
NPC1	O15118-1.2	R1173I	Pathogenic	0.875
NPC1	O15118-1.2	R1173K	Pathogenic	0.706
NPC1	O15118-1.2	R1173L	Pathogenic	0.831
NPC1	O15118-1.2	R1173M	Pathogenic	0.796
NPC1	O15118-1.2	R1173N	Pathogenic	0.853
NPC1	O15118-1.2	R1173P	Pathogenic	0.893
NPC1	O15118-1.2	R1173Q	Pathogenic	0.756
NPC1	O15118-1.2	R1173S	Pathogenic	0.89
NPC1	O15118-1.2	R1173T	Pathogenic	0.867
NPC1	O15118-1.2	R1173V	Pathogenic	0.905
NPC1	O15118-1.2	R1173W	Pathogenic	0.851
NPC1	O15118-1.2	R1173Y	Pathogenic	0.85
NPC1	O15118-1.2	A1174C	Pathogenic	0.687
NPC1	O15118-1.2	A1174D	Pathogenic	0.811
NPC1	O15118-1.2	A1174E	Pathogenic	0.772
NPC1	O15118-1.2	A1174F	Pathogenic	0.83
NPC1	O15118-1.2	A1174G	Pathogenic	0.713
NPC1	O15118-1.2	A1174H	Pathogenic	0.872
NPC1	O15118-1.2	A1174I	Pathogenic	0.756
NPC1	O15118-1.2	A1174K	Pathogenic	0.78
NPC1	O15118-1.2	A1174L	Pathogenic	0.762
NPC1	O15118-1.2	A1174M	Pathogenic	0.789
NPC1	O15118-1.2	A1174N	Pathogenic	0.824
NPC1	O15118-1.2	A1174P	Pathogenic	0.783
NPC1	O15118-1.2	A1174Q	Pathogenic	0.801
NPC1	O15118-1.2	A1174R	Pathogenic	0.792
NPC1	O15118-1.2	A1174S	Pathogenic	0.607
NPC1	O15118-1.2	A1174T	Pathogenic	0.738
NPC1	O15118-1.2	A1174V	Pathogenic	0.695
NPC1	O15118-1.2	A1174W	Pathogenic	0.88
NPC1	O15118-1.2	A1174Y	Pathogenic	0.87
NPC1	O15118-1.2	F1175A	Pathogenic	0.947
NPC1	O15118-1.2	F1175C	Pathogenic	0.952
NPC1	O15118-1.2	F1175D	Pathogenic	0.94
NPC1	O15118-1.2	F1175E	Pathogenic	0.937
NPC1	O15118-1.2	F1175G	Pathogenic	0.964
NPC1	O15118-1.2	F1175H	Pathogenic	0.893
NPC1	O15118-1.2	F1175I	Pathogenic	0.904
NPC1	O15118-1.2	F1175K	Pathogenic	0.918
NPC1	O15118-1.2	F1175L	Pathogenic	0.902
NPC1	O15118-1.2	F1175M	Pathogenic	0.888
NPC1	O15118-1.2	F1175N	Pathogenic	0.942
NPC1	O15118-1.2	F1175P	Pathogenic	0.975
NPC1	O15118-1.2	F1175Q	Pathogenic	0.943
NPC1	O15118-1.2	F1175R	Pathogenic	0.924
NPC1	O15118-1.2	F1175S	Pathogenic	0.938
NPC1	O15118-1.2	F1175T	Pathogenic	0.937
NPC1	O15118-1.2	F1175V	Pathogenic	0.928
NPC1	O15118-1.2	F1175W	Pathogenic	0.86
NPC1	O15118-1.2	F1175Y	Pathogenic	0.687
NPC1	O15118-1.2	T1176A	Pathogenic	0.558
NPC1	O15118-1.2	T1176C	Pathogenic	0.57
NPC1	O15118-1.2	T1176D	Pathogenic	0.538
NPC1	O15118-1.2	T1176E	Pathogenic	0.569
NPC1	O15118-1.2	T1176F	Pathogenic	0.648
NPC1	O15118-1.2	T1176G	Pathogenic	0.741
NPC1	O15118-1.2	T1176H	Pathogenic	0.726
NPC1	O15118-1.2	T1176I	Pathogenic	0.538
NPC1	O15118-1.2	T1176K	Pathogenic	0.579
NPC1	O15118-1.2	T1176L	Pathogenic	0.547
NPC1	O15118-1.2	T1176M	Pathogenic	0.585
NPC1	O15118-1.2	T1176N	Neutral	0.457
NPC1	O15118-1.2	T1176P	Pathogenic	0.585
NPC1	O15118-1.2	T1176Q	Pathogenic	0.61
NPC1	O15118-1.2	T1176R	Pathogenic	0.597
NPC1	O15118-1.2	T1176S	Neutral	0.433
NPC1	O15118-1.2	T1176V	Neutral	0.462
NPC1	O15118-1.2	T1176W	Pathogenic	0.652
NPC1	O15118-1.2	T1176Y	Pathogenic	0.715
NPC1	O15118-1.2	V1177A	Neutral	0.413
NPC1	O15118-1.2	V1177C	Pathogenic	0.536
NPC1	O15118-1.2	V1177D	Pathogenic	0.575
NPC1	O15118-1.2	V1177E	Neutral	0.475
NPC1	O15118-1.2	V1177F	Pathogenic	0.524
NPC1	O15118-1.2	V1177G	Pathogenic	0.694
NPC1	O15118-1.2	V1177H	Pathogenic	0.645
NPC1	O15118-1.2	V1177I	Neutral	0.18
NPC1	O15118-1.2	V1177K	Neutral	0.485
NPC1	O15118-1.2	V1177L	Neutral	0.329
NPC1	O15118-1.2	V1177M	Neutral	0.365
NPC1	O15118-1.2	V1177N	Pathogenic	0.581
NPC1	O15118-1.2	V1177P	Pathogenic	0.603
NPC1	O15118-1.2	V1177Q	Pathogenic	0.517
NPC1	O15118-1.2	V1177R	Pathogenic	0.598
NPC1	O15118-1.2	V1177S	Pathogenic	0.567
NPC1	O15118-1.2	V1177T	Neutral	0.371
NPC1	O15118-1.2	V1177W	Pathogenic	0.708
NPC1	O15118-1.2	V1177Y	Pathogenic	0.559
NPC1	O15118-1.2	S1178A	Pathogenic	0.815
NPC1	O15118-1.2	S1178C	Pathogenic	0.888
NPC1	O15118-1.2	S1178D	Pathogenic	0.859
NPC1	O15118-1.2	S1178E	Pathogenic	0.877
NPC1	O15118-1.2	S1178F	Pathogenic	0.923
NPC1	O15118-1.2	S1178G	Pathogenic	0.889
NPC1	O15118-1.2	S1178H	Pathogenic	0.927
NPC1	O15118-1.2	S1178I	Pathogenic	0.918
NPC1	O15118-1.2	S1178K	Pathogenic	0.881
NPC1	O15118-1.2	S1178L	Pathogenic	0.92
NPC1	O15118-1.2	S1178M	Pathogenic	0.902
NPC1	O15118-1.2	S1178N	Pathogenic	0.819
NPC1	O15118-1.2	S1178P	Pathogenic	0.899
NPC1	O15118-1.2	S1178Q	Pathogenic	0.894
NPC1	O15118-1.2	S1178R	Pathogenic	0.922
NPC1	O15118-1.2	S1178T	Pathogenic	0.83
NPC1	O15118-1.2	S1178V	Pathogenic	0.924
NPC1	O15118-1.2	S1178W	Pathogenic	0.947
NPC1	O15118-1.2	S1178Y	Pathogenic	0.943
NPC1	O15118-1.2	M1179A	Neutral	0.278
NPC1	O15118-1.2	M1179C	Neutral	0.3
NPC1	O15118-1.2	M1179D	Neutral	0.335
NPC1	O15118-1.2	M1179E	Neutral	0.243
NPC1	O15118-1.2	M1179F	Neutral	0.183
NPC1	O15118-1.2	M1179G	Neutral	0.457
NPC1	O15118-1.2	M1179H	Neutral	0.282
NPC1	O15118-1.2	M1179I	Neutral	0.124
NPC1	O15118-1.2	M1179K	Neutral	0.159
NPC1	O15118-1.2	M1179L	Neutral	0.091
NPC1	O15118-1.2	M1179N	Neutral	0.26
NPC1	O15118-1.2	M1179P	Neutral	0.361
NPC1	O15118-1.2	M1179Q	Neutral	0.142
NPC1	O15118-1.2	M1179R	Neutral	0.169
NPC1	O15118-1.2	M1179S	Neutral	0.249
NPC1	O15118-1.2	M1179T	Neutral	0.244
NPC1	O15118-1.2	M1179V	Neutral	0.161
NPC1	O15118-1.2	M1179W	Neutral	0.251
NPC1	O15118-1.2	M1179Y	Neutral	0.273
NPC1	O15118-1.2	K1180A	Pathogenic	0.595
NPC1	O15118-1.2	K1180C	Pathogenic	0.693
NPC1	O15118-1.2	K1180D	Pathogenic	0.645
NPC1	O15118-1.2	K1180E	Neutral	0.419
NPC1	O15118-1.2	K1180F	Pathogenic	0.562
NPC1	O15118-1.2	K1180G	Pathogenic	0.728
NPC1	O15118-1.2	K1180H	Pathogenic	0.533
NPC1	O15118-1.2	K1180I	Pathogenic	0.577
NPC1	O15118-1.2	K1180L	Neutral	0.49
NPC1	O15118-1.2	K1180M	Neutral	0.433
NPC1	O15118-1.2	K1180N	Pathogenic	0.531
NPC1	O15118-1.2	K1180P	Pathogenic	0.527
NPC1	O15118-1.2	K1180Q	Neutral	0.378
NPC1	O15118-1.2	K1180R	Neutral	0.336
NPC1	O15118-1.2	K1180S	Pathogenic	0.519
NPC1	O15118-1.2	K1180T	Pathogenic	0.56
NPC1	O15118-1.2	K1180V	Pathogenic	0.559
NPC1	O15118-1.2	K1180W	Pathogenic	0.566
NPC1	O15118-1.2	K1180Y	Pathogenic	0.544
NPC1	O15118-1.2	G1181A	Neutral	0.158
NPC1	O15118-1.2	G1181C	Neutral	0.348
NPC1	O15118-1.2	G1181D	Neutral	0.215
NPC1	O15118-1.2	G1181E	Neutral	0.319
NPC1	O15118-1.2	G1181F	Neutral	0.355
NPC1	O15118-1.2	G1181H	Neutral	0.369
NPC1	O15118-1.2	G1181I	Neutral	0.429
NPC1	O15118-1.2	G1181K	Neutral	0.328
NPC1	O15118-1.2	G1181L	Neutral	0.438
NPC1	O15118-1.2	G1181M	Neutral	0.382
NPC1	O15118-1.2	G1181N	Neutral	0.168
NPC1	O15118-1.2	G1181P	Neutral	0.289
NPC1	O15118-1.2	G1181Q	Neutral	0.357
NPC1	O15118-1.2	G1181R	Neutral	0.344
NPC1	O15118-1.2	G1181S	Neutral	0.175
NPC1	O15118-1.2	G1181T	Neutral	0.325
NPC1	O15118-1.2	G1181V	Neutral	0.357
NPC1	O15118-1.2	G1181W	Neutral	0.275
NPC1	O15118-1.2	G1181Y	Neutral	0.429
NPC1	O15118-1.2	S1182A	Neutral	0.446
NPC1	O15118-1.2	S1182C	Pathogenic	0.592
NPC1	O15118-1.2	S1182D	Pathogenic	0.528
NPC1	O15118-1.2	S1182E	Pathogenic	0.566
NPC1	O15118-1.2	S1182F	Pathogenic	0.687
NPC1	O15118-1.2	S1182G	Pathogenic	0.595
NPC1	O15118-1.2	S1182H	Pathogenic	0.7
NPC1	O15118-1.2	S1182I	Pathogenic	0.671
NPC1	O15118-1.2	S1182K	Pathogenic	0.575
NPC1	O15118-1.2	S1182L	Pathogenic	0.679
NPC1	O15118-1.2	S1182M	Pathogenic	0.627
NPC1	O15118-1.2	S1182N	Neutral	0.453
NPC1	O15118-1.2	S1182P	Pathogenic	0.619
NPC1	O15118-1.2	S1182Q	Pathogenic	0.607
NPC1	O15118-1.2	S1182R	Pathogenic	0.682
NPC1	O15118-1.2	S1182T	Neutral	0.471
NPC1	O15118-1.2	S1182V	Pathogenic	0.689
NPC1	O15118-1.2	S1182W	Pathogenic	0.766
NPC1	O15118-1.2	S1182Y	Pathogenic	0.75
NPC1	O15118-1.2	R1183A	Pathogenic	0.925
NPC1	O15118-1.2	R1183C	Pathogenic	0.95
NPC1	O15118-1.2	R1183D	Pathogenic	0.957
NPC1	O15118-1.2	R1183E	Pathogenic	0.899
NPC1	O15118-1.2	R1183F	Pathogenic	0.915
NPC1	O15118-1.2	R1183G	Pathogenic	0.957
NPC1	O15118-1.2	R1183H	Pathogenic	0.867
NPC1	O15118-1.2	R1183I	Pathogenic	0.92
NPC1	O15118-1.2	R1183K	Pathogenic	0.798
NPC1	O15118-1.2	R1183L	Pathogenic	0.89
NPC1	O15118-1.2	R1183M	Pathogenic	0.865
NPC1	O15118-1.2	R1183N	Pathogenic	0.905
NPC1	O15118-1.2	R1183P	Pathogenic	0.932
NPC1	O15118-1.2	R1183Q	Pathogenic	0.836
NPC1	O15118-1.2	R1183S	Pathogenic	0.93
NPC1	O15118-1.2	R1183T	Pathogenic	0.914
NPC1	O15118-1.2	R1183V	Pathogenic	0.94
NPC1	O15118-1.2	R1183W	Pathogenic	0.903
NPC1	O15118-1.2	R1183Y	Pathogenic	0.903
NPC1	O15118-1.2	V1184A	Pathogenic	0.54
NPC1	O15118-1.2	V1184C	Pathogenic	0.658
NPC1	O15118-1.2	V1184D	Pathogenic	0.693
NPC1	O15118-1.2	V1184E	Pathogenic	0.602
NPC1	O15118-1.2	V1184F	Pathogenic	0.648
NPC1	O15118-1.2	V1184G	Pathogenic	0.791
NPC1	O15118-1.2	V1184H	Pathogenic	0.752
NPC1	O15118-1.2	V1184I	Neutral	0.268
NPC1	O15118-1.2	V1184K	Pathogenic	0.611
NPC1	O15118-1.2	V1184L	Neutral	0.451
NPC1	O15118-1.2	V1184M	Neutral	0.49
NPC1	O15118-1.2	V1184N	Pathogenic	0.699
NPC1	O15118-1.2	V1184P	Pathogenic	0.717
NPC1	O15118-1.2	V1184Q	Pathogenic	0.642
NPC1	O15118-1.2	V1184R	Pathogenic	0.714
NPC1	O15118-1.2	V1184S	Pathogenic	0.686
NPC1	O15118-1.2	V1184T	Neutral	0.497
NPC1	O15118-1.2	V1184W	Pathogenic	0.802
NPC1	O15118-1.2	V1184Y	Pathogenic	0.68
NPC1	O15118-1.2	E1185A	Neutral	0.486
NPC1	O15118-1.2	E1185C	Pathogenic	0.682
NPC1	O15118-1.2	E1185D	Neutral	0.252
NPC1	O15118-1.2	E1185F	Pathogenic	0.532
NPC1	O15118-1.2	E1185G	Pathogenic	0.634
NPC1	O15118-1.2	E1185H	Neutral	0.359
NPC1	O15118-1.2	E1185I	Pathogenic	0.514
NPC1	O15118-1.2	E1185K	Neutral	0.326
NPC1	O15118-1.2	E1185L	Pathogenic	0.523
NPC1	O15118-1.2	E1185M	Neutral	0.465
NPC1	O15118-1.2	E1185N	Neutral	0.422
NPC1	O15118-1.2	E1185P	Neutral	0.418
NPC1	O15118-1.2	E1185Q	Neutral	0.221
NPC1	O15118-1.2	E1185R	Neutral	0.434
NPC1	O15118-1.2	E1185S	Neutral	0.41
NPC1	O15118-1.2	E1185T	Neutral	0.452
NPC1	O15118-1.2	E1185V	Neutral	0.45
NPC1	O15118-1.2	E1185W	Pathogenic	0.536
NPC1	O15118-1.2	E1185Y	Pathogenic	0.514
NPC1	O15118-1.2	R1186A	Pathogenic	0.953
NPC1	O15118-1.2	R1186C	Pathogenic	0.969
NPC1	O15118-1.2	R1186D	Pathogenic	0.974
NPC1	O15118-1.2	R1186E	Pathogenic	0.937
NPC1	O15118-1.2	R1186F	Pathogenic	0.947
NPC1	O15118-1.2	R1186G	Pathogenic	0.974
NPC1	O15118-1.2	R1186H	Pathogenic	0.916
NPC1	O15118-1.2	R1186I	Pathogenic	0.95
NPC1	O15118-1.2	R1186K	Pathogenic	0.868
NPC1	O15118-1.2	R1186L	Pathogenic	0.931
NPC1	O15118-1.2	R1186M	Pathogenic	0.914
NPC1	O15118-1.2	R1186N	Pathogenic	0.94
NPC1	O15118-1.2	R1186P	Pathogenic	0.958
NPC1	O15118-1.2	R1186Q	Pathogenic	0.895
NPC1	O15118-1.2	R1186S	Pathogenic	0.957
NPC1	O15118-1.2	R1186T	Pathogenic	0.947
NPC1	O15118-1.2	R1186V	Pathogenic	0.963
NPC1	O15118-1.2	R1186W	Pathogenic	0.94
NPC1	O15118-1.2	R1186Y	Pathogenic	0.939
NPC1	O15118-1.2	A1187C	Pathogenic	0.761
NPC1	O15118-1.2	A1187D	Pathogenic	0.862
NPC1	O15118-1.2	A1187E	Pathogenic	0.831
NPC1	O15118-1.2	A1187F	Pathogenic	0.877
NPC1	O15118-1.2	A1187G	Pathogenic	0.783
NPC1	O15118-1.2	A1187H	Pathogenic	0.908
NPC1	O15118-1.2	A1187I	Pathogenic	0.818
NPC1	O15118-1.2	A1187K	Pathogenic	0.837
NPC1	O15118-1.2	A1187L	Pathogenic	0.823
NPC1	O15118-1.2	A1187M	Pathogenic	0.845
NPC1	O15118-1.2	A1187N	Pathogenic	0.872
NPC1	O15118-1.2	A1187P	Pathogenic	0.84
NPC1	O15118-1.2	A1187Q	Pathogenic	0.854
NPC1	O15118-1.2	A1187R	Pathogenic	0.847
NPC1	O15118-1.2	A1187S	Pathogenic	0.691
NPC1	O15118-1.2	A1187T	Pathogenic	0.804
NPC1	O15118-1.2	A1187V	Pathogenic	0.768
NPC1	O15118-1.2	A1187W	Pathogenic	0.914
NPC1	O15118-1.2	A1187Y	Pathogenic	0.907
NPC1	O15118-1.2	E1188A	Pathogenic	0.613
NPC1	O15118-1.2	E1188C	Pathogenic	0.782
NPC1	O15118-1.2	E1188D	Neutral	0.361
NPC1	O15118-1.2	E1188F	Pathogenic	0.656
NPC1	O15118-1.2	E1188G	Pathogenic	0.744
NPC1	O15118-1.2	E1188H	Neutral	0.484
NPC1	O15118-1.2	E1188I	Pathogenic	0.639
NPC1	O15118-1.2	E1188K	Neutral	0.448
NPC1	O15118-1.2	E1188L	Pathogenic	0.647
NPC1	O15118-1.2	E1188M	Pathogenic	0.593
NPC1	O15118-1.2	E1188N	Pathogenic	0.551
NPC1	O15118-1.2	E1188P	Pathogenic	0.546
NPC1	O15118-1.2	E1188Q	Neutral	0.322
NPC1	O15118-1.2	E1188R	Pathogenic	0.562
NPC1	O15118-1.2	E1188S	Pathogenic	0.538
NPC1	O15118-1.2	E1188T	Pathogenic	0.58
NPC1	O15118-1.2	E1188V	Pathogenic	0.578
NPC1	O15118-1.2	E1188W	Pathogenic	0.659
NPC1	O15118-1.2	E1188Y	Pathogenic	0.639
NPC1	O15118-1.2	E1189A	Pathogenic	0.758
NPC1	O15118-1.2	E1189C	Pathogenic	0.877
NPC1	O15118-1.2	E1189D	Pathogenic	0.528
NPC1	O15118-1.2	E1189F	Pathogenic	0.79
NPC1	O15118-1.2	E1189G	Pathogenic	0.851
NPC1	O15118-1.2	E1189H	Pathogenic	0.649
NPC1	O15118-1.2	E1189I	Pathogenic	0.778
NPC1	O15118-1.2	E1189K	Pathogenic	0.616
NPC1	O15118-1.2	E1189L	Pathogenic	0.784
NPC1	O15118-1.2	E1189M	Pathogenic	0.742
NPC1	O15118-1.2	E1189N	Pathogenic	0.708
NPC1	O15118-1.2	E1189P	Pathogenic	0.704
NPC1	O15118-1.2	E1189Q	Neutral	0.484
NPC1	O15118-1.2	E1189R	Pathogenic	0.717
NPC1	O15118-1.2	E1189S	Pathogenic	0.698
NPC1	O15118-1.2	E1189T	Pathogenic	0.732
NPC1	O15118-1.2	E1189V	Pathogenic	0.73
NPC1	O15118-1.2	E1189W	Pathogenic	0.793
NPC1	O15118-1.2	E1189Y	Pathogenic	0.778
NPC1	O15118-1.2	A1190C	Pathogenic	0.793
NPC1	O15118-1.2	A1190D	Pathogenic	0.882
NPC1	O15118-1.2	A1190E	Pathogenic	0.856
NPC1	O15118-1.2	A1190F	Pathogenic	0.895
NPC1	O15118-1.2	A1190G	Pathogenic	0.813
NPC1	O15118-1.2	A1190H	Pathogenic	0.922
NPC1	O15118-1.2	A1190I	Pathogenic	0.844
NPC1	O15118-1.2	A1190K	Pathogenic	0.861
NPC1	O15118-1.2	A1190L	Pathogenic	0.848
NPC1	O15118-1.2	A1190M	Pathogenic	0.867
NPC1	O15118-1.2	A1190N	Pathogenic	0.891
NPC1	O15118-1.2	A1190P	Pathogenic	0.863
NPC1	O15118-1.2	A1190Q	Pathogenic	0.875
NPC1	O15118-1.2	A1190R	Pathogenic	0.869
NPC1	O15118-1.2	A1190S	Pathogenic	0.729
NPC1	O15118-1.2	A1190T	Pathogenic	0.831
NPC1	O15118-1.2	A1190V	Pathogenic	0.799
NPC1	O15118-1.2	A1190W	Pathogenic	0.927
NPC1	O15118-1.2	A1190Y	Pathogenic	0.921
NPC1	O15118-1.2	L1191A	Pathogenic	0.843
NPC1	O15118-1.2	L1191C	Pathogenic	0.857
NPC1	O15118-1.2	L1191D	Pathogenic	0.911
NPC1	O15118-1.2	L1191E	Pathogenic	0.868
NPC1	O15118-1.2	L1191F	Pathogenic	0.81
NPC1	O15118-1.2	L1191G	Pathogenic	0.945
NPC1	O15118-1.2	L1191H	Pathogenic	0.889
NPC1	O15118-1.2	L1191I	Pathogenic	0.647
NPC1	O15118-1.2	L1191K	Pathogenic	0.795
NPC1	O15118-1.2	L1191M	Pathogenic	0.618
NPC1	O15118-1.2	L1191N	Pathogenic	0.878
NPC1	O15118-1.2	L1191P	Pathogenic	0.92
NPC1	O15118-1.2	L1191Q	Pathogenic	0.833
NPC1	O15118-1.2	L1191R	Pathogenic	0.807
NPC1	O15118-1.2	L1191S	Pathogenic	0.871
NPC1	O15118-1.2	L1191T	Pathogenic	0.818
NPC1	O15118-1.2	L1191V	Pathogenic	0.727
NPC1	O15118-1.2	L1191W	Pathogenic	0.903
NPC1	O15118-1.2	L1191Y	Pathogenic	0.839
NPC1	O15118-1.2	A1192C	Neutral	0.357
NPC1	O15118-1.2	A1192D	Pathogenic	0.52
NPC1	O15118-1.2	A1192E	Neutral	0.462
NPC1	O15118-1.2	A1192F	Pathogenic	0.553
NPC1	O15118-1.2	A1192G	Neutral	0.385
NPC1	O15118-1.2	A1192H	Pathogenic	0.632
NPC1	O15118-1.2	A1192I	Neutral	0.439
NPC1	O15118-1.2	A1192K	Neutral	0.472
NPC1	O15118-1.2	A1192L	Neutral	0.447
NPC1	O15118-1.2	A1192M	Neutral	0.486
NPC1	O15118-1.2	A1192N	Pathogenic	0.541
NPC1	O15118-1.2	A1192P	Neutral	0.477
NPC1	O15118-1.2	A1192Q	Pathogenic	0.504
NPC1	O15118-1.2	A1192R	Neutral	0.49
NPC1	O15118-1.2	A1192S	Neutral	0.28
NPC1	O15118-1.2	A1192T	Neutral	0.416
NPC1	O15118-1.2	A1192V	Neutral	0.366
NPC1	O15118-1.2	A1192W	Pathogenic	0.649
NPC1	O15118-1.2	A1192Y	Pathogenic	0.628
NPC1	O15118-1.2	H1193A	Pathogenic	0.738
NPC1	O15118-1.2	H1193C	Pathogenic	0.747
NPC1	O15118-1.2	H1193D	Pathogenic	0.565
NPC1	O15118-1.2	H1193E	Neutral	0.453
NPC1	O15118-1.2	H1193F	Neutral	0.488
NPC1	O15118-1.2	H1193G	Pathogenic	0.762
NPC1	O15118-1.2	H1193I	Pathogenic	0.657
NPC1	O15118-1.2	H1193K	Pathogenic	0.532
NPC1	O15118-1.2	H1193L	Pathogenic	0.665
NPC1	O15118-1.2	H1193M	Pathogenic	0.612
NPC1	O15118-1.2	H1193N	Neutral	0.382
NPC1	O15118-1.2	H1193P	Pathogenic	0.681
NPC1	O15118-1.2	H1193Q	Neutral	0.48
NPC1	O15118-1.2	H1193R	Neutral	0.454
NPC1	O15118-1.2	H1193S	Pathogenic	0.649
NPC1	O15118-1.2	H1193T	Pathogenic	0.71
NPC1	O15118-1.2	H1193V	Pathogenic	0.709
NPC1	O15118-1.2	H1193W	Pathogenic	0.587
NPC1	O15118-1.2	H1193Y	Neutral	0.29
NPC1	O15118-1.2	M1194A	Pathogenic	0.953
NPC1	O15118-1.2	M1194C	Pathogenic	0.958
NPC1	O15118-1.2	M1194D	Pathogenic	0.964
NPC1	O15118-1.2	M1194E	Pathogenic	0.945
NPC1	O15118-1.2	M1194F	Pathogenic	0.923
NPC1	O15118-1.2	M1194G	Pathogenic	0.978
NPC1	O15118-1.2	M1194H	Pathogenic	0.954
NPC1	O15118-1.2	M1194I	Pathogenic	0.883
NPC1	O15118-1.2	M1194K	Pathogenic	0.91
NPC1	O15118-1.2	M1194L	Pathogenic	0.841
NPC1	O15118-1.2	M1194N	Pathogenic	0.949
NPC1	O15118-1.2	M1194P	Pathogenic	0.968
NPC1	O15118-1.2	M1194Q	Pathogenic	0.898
NPC1	O15118-1.2	M1194R	Pathogenic	0.916
NPC1	O15118-1.2	M1194S	Pathogenic	0.946
NPC1	O15118-1.2	M1194T	Pathogenic	0.945
NPC1	O15118-1.2	M1194V	Pathogenic	0.911
NPC1	O15118-1.2	M1194W	Pathogenic	0.947
NPC1	O15118-1.2	M1194Y	Pathogenic	0.952
NPC1	O15118-1.2	G1195A	Pathogenic	0.929
NPC1	O15118-1.2	G1195C	Pathogenic	0.974
NPC1	O15118-1.2	G1195D	Pathogenic	0.95
NPC1	O15118-1.2	G1195E	Pathogenic	0.97
NPC1	O15118-1.2	G1195F	Pathogenic	0.974
NPC1	O15118-1.2	G1195H	Pathogenic	0.976
NPC1	O15118-1.2	G1195I	Pathogenic	0.981
NPC1	O15118-1.2	G1195K	Pathogenic	0.971
NPC1	O15118-1.2	G1195L	Pathogenic	0.982
NPC1	O15118-1.2	G1195M	Pathogenic	0.977
NPC1	O15118-1.2	G1195N	Pathogenic	0.934
NPC1	O15118-1.2	G1195P	Pathogenic	0.966
NPC1	O15118-1.2	G1195Q	Pathogenic	0.975
NPC1	O15118-1.2	G1195R	Pathogenic	0.973
NPC1	O15118-1.2	G1195S	Pathogenic	0.936
NPC1	O15118-1.2	G1195T	Pathogenic	0.971
NPC1	O15118-1.2	G1195V	Pathogenic	0.975
NPC1	O15118-1.2	G1195W	Pathogenic	0.963
NPC1	O15118-1.2	G1195Y	Pathogenic	0.981
NPC1	O15118-1.2	S1196A	Pathogenic	0.623
NPC1	O15118-1.2	S1196C	Pathogenic	0.748
NPC1	O15118-1.2	S1196D	Pathogenic	0.696
NPC1	O15118-1.2	S1196E	Pathogenic	0.728
NPC1	O15118-1.2	S1196F	Pathogenic	0.818
NPC1	O15118-1.2	S1196G	Pathogenic	0.751
NPC1	O15118-1.2	S1196H	Pathogenic	0.827
NPC1	O15118-1.2	S1196I	Pathogenic	0.807
NPC1	O15118-1.2	S1196K	Pathogenic	0.736
NPC1	O15118-1.2	S1196L	Pathogenic	0.813
NPC1	O15118-1.2	S1196M	Pathogenic	0.775
NPC1	O15118-1.2	S1196N	Pathogenic	0.63
NPC1	O15118-1.2	S1196P	Pathogenic	0.769
NPC1	O15118-1.2	S1196Q	Pathogenic	0.76
NPC1	O15118-1.2	S1196R	Pathogenic	0.815
NPC1	O15118-1.2	S1196T	Pathogenic	0.646
NPC1	O15118-1.2	S1196V	Pathogenic	0.82
NPC1	O15118-1.2	S1196W	Pathogenic	0.871
NPC1	O15118-1.2	S1196Y	Pathogenic	0.86
NPC1	O15118-1.2	S1197A	Neutral	0.496
NPC1	O15118-1.2	S1197C	Pathogenic	0.64
NPC1	O15118-1.2	S1197D	Pathogenic	0.578
NPC1	O15118-1.2	S1197E	Pathogenic	0.615
NPC1	O15118-1.2	S1197F	Pathogenic	0.729
NPC1	O15118-1.2	S1197G	Pathogenic	0.643
NPC1	O15118-1.2	S1197H	Pathogenic	0.741
NPC1	O15118-1.2	S1197I	Pathogenic	0.715
NPC1	O15118-1.2	S1197K	Pathogenic	0.624
NPC1	O15118-1.2	S1197L	Pathogenic	0.722
NPC1	O15118-1.2	S1197M	Pathogenic	0.673
NPC1	O15118-1.2	S1197N	Pathogenic	0.504
NPC1	O15118-1.2	S1197P	Pathogenic	0.665
NPC1	O15118-1.2	S1197Q	Pathogenic	0.654
NPC1	O15118-1.2	S1197R	Pathogenic	0.725
NPC1	O15118-1.2	S1197T	Pathogenic	0.522
NPC1	O15118-1.2	S1197V	Pathogenic	0.731
NPC1	O15118-1.2	S1197W	Pathogenic	0.801
NPC1	O15118-1.2	S1197Y	Pathogenic	0.786
NPC1	O15118-1.2	V1198A	Pathogenic	0.542
NPC1	O15118-1.2	V1198C	Pathogenic	0.66
NPC1	O15118-1.2	V1198D	Pathogenic	0.694
NPC1	O15118-1.2	V1198E	Pathogenic	0.603
NPC1	O15118-1.2	V1198F	Pathogenic	0.649
NPC1	O15118-1.2	V1198G	Pathogenic	0.792
NPC1	O15118-1.2	V1198H	Pathogenic	0.753
NPC1	O15118-1.2	V1198I	Neutral	0.269
NPC1	O15118-1.2	V1198K	Pathogenic	0.613
NPC1	O15118-1.2	V1198L	Neutral	0.452
NPC1	O15118-1.2	V1198M	Neutral	0.491
NPC1	O15118-1.2	V1198N	Pathogenic	0.7
NPC1	O15118-1.2	V1198P	Pathogenic	0.718
NPC1	O15118-1.2	V1198Q	Pathogenic	0.643
NPC1	O15118-1.2	V1198R	Pathogenic	0.715
NPC1	O15118-1.2	V1198S	Pathogenic	0.687
NPC1	O15118-1.2	V1198T	Neutral	0.498
NPC1	O15118-1.2	V1198W	Pathogenic	0.803
NPC1	O15118-1.2	V1198Y	Pathogenic	0.681
NPC1	O15118-1.2	F1199A	Pathogenic	0.713
NPC1	O15118-1.2	F1199C	Pathogenic	0.734
NPC1	O15118-1.2	F1199D	Pathogenic	0.688
NPC1	O15118-1.2	F1199E	Pathogenic	0.674
NPC1	O15118-1.2	F1199G	Pathogenic	0.787
NPC1	O15118-1.2	F1199H	Pathogenic	0.539
NPC1	O15118-1.2	F1199I	Pathogenic	0.569
NPC1	O15118-1.2	F1199K	Pathogenic	0.611
NPC1	O15118-1.2	F1199L	Pathogenic	0.563
NPC1	O15118-1.2	F1199M	Pathogenic	0.525
NPC1	O15118-1.2	F1199N	Pathogenic	0.694
NPC1	O15118-1.2	F1199P	Pathogenic	0.843
NPC1	O15118-1.2	F1199Q	Pathogenic	0.697
NPC1	O15118-1.2	F1199R	Pathogenic	0.628
NPC1	O15118-1.2	F1199S	Pathogenic	0.681
NPC1	O15118-1.2	F1199T	Pathogenic	0.676
NPC1	O15118-1.2	F1199V	Pathogenic	0.644
NPC1	O15118-1.2	F1199W	Neutral	0.462
NPC1	O15118-1.2	F1199Y	Neutral	0.235
NPC1	O15118-1.2	S1200A	Pathogenic	0.549
NPC1	O15118-1.2	S1200C	Pathogenic	0.687
NPC1	O15118-1.2	S1200D	Pathogenic	0.628
NPC1	O15118-1.2	S1200E	Pathogenic	0.663
NPC1	O15118-1.2	S1200F	Pathogenic	0.768
NPC1	O15118-1.2	S1200G	Pathogenic	0.69
NPC1	O15118-1.2	S1200H	Pathogenic	0.779
NPC1	O15118-1.2	S1200I	Pathogenic	0.755
NPC1	O15118-1.2	S1200K	Pathogenic	0.672
NPC1	O15118-1.2	S1200L	Pathogenic	0.762
NPC1	O15118-1.2	S1200M	Pathogenic	0.718
NPC1	O15118-1.2	S1200N	Pathogenic	0.556
NPC1	O15118-1.2	S1200P	Pathogenic	0.71
NPC1	O15118-1.2	S1200Q	Pathogenic	0.7
NPC1	O15118-1.2	S1200R	Pathogenic	0.764
NPC1	O15118-1.2	S1200T	Pathogenic	0.574
NPC1	O15118-1.2	S1200V	Pathogenic	0.77
NPC1	O15118-1.2	S1200W	Pathogenic	0.832
NPC1	O15118-1.2	S1200Y	Pathogenic	0.819
NPC1	O15118-1.2	G1201A	Pathogenic	0.781
NPC1	O15118-1.2	G1201C	Pathogenic	0.91
NPC1	O15118-1.2	G1201D	Pathogenic	0.839
NPC1	O15118-1.2	G1201E	Pathogenic	0.899
NPC1	O15118-1.2	G1201F	Pathogenic	0.913
NPC1	O15118-1.2	G1201H	Pathogenic	0.918
NPC1	O15118-1.2	G1201I	Pathogenic	0.935
NPC1	O15118-1.2	G1201K	Pathogenic	0.903
NPC1	O15118-1.2	G1201L	Pathogenic	0.937
NPC1	O15118-1.2	G1201M	Pathogenic	0.922
NPC1	O15118-1.2	G1201N	Pathogenic	0.794
NPC1	O15118-1.2	G1201P	Pathogenic	0.885
NPC1	O15118-1.2	G1201Q	Pathogenic	0.913
NPC1	O15118-1.2	G1201R	Pathogenic	0.909
NPC1	O15118-1.2	G1201S	Pathogenic	0.802
NPC1	O15118-1.2	G1201T	Pathogenic	0.902
NPC1	O15118-1.2	G1201V	Pathogenic	0.913
NPC1	O15118-1.2	G1201W	Pathogenic	0.878
NPC1	O15118-1.2	G1201Y	Pathogenic	0.935
NPC1	O15118-1.2	I1202A	Pathogenic	0.711
NPC1	O15118-1.2	I1202C	Pathogenic	0.733
NPC1	O15118-1.2	I1202D	Pathogenic	0.763
NPC1	O15118-1.2	I1202E	Pathogenic	0.751
NPC1	O15118-1.2	I1202F	Pathogenic	0.675
NPC1	O15118-1.2	I1202G	Pathogenic	0.888
NPC1	O15118-1.2	I1202H	Pathogenic	0.787
NPC1	O15118-1.2	I1202K	Pathogenic	0.724
NPC1	O15118-1.2	I1202L	Neutral	0.466
NPC1	O15118-1.2	I1202M	Pathogenic	0.523
NPC1	O15118-1.2	I1202N	Pathogenic	0.768
NPC1	O15118-1.2	I1202P	Pathogenic	0.842
NPC1	O15118-1.2	I1202Q	Pathogenic	0.771
NPC1	O15118-1.2	I1202R	Pathogenic	0.738
NPC1	O15118-1.2	I1202S	Pathogenic	0.757
NPC1	O15118-1.2	I1202T	Pathogenic	0.674
NPC1	O15118-1.2	I1202V	Neutral	0.362
NPC1	O15118-1.2	I1202W	Pathogenic	0.871
NPC1	O15118-1.2	I1202Y	Pathogenic	0.706
NPC1	O15118-1.2	T1203A	Pathogenic	0.714
NPC1	O15118-1.2	T1203C	Pathogenic	0.723
NPC1	O15118-1.2	T1203D	Pathogenic	0.696
NPC1	O15118-1.2	T1203E	Pathogenic	0.723
NPC1	O15118-1.2	T1203F	Pathogenic	0.784
NPC1	O15118-1.2	T1203G	Pathogenic	0.85
NPC1	O15118-1.2	T1203H	Pathogenic	0.84
NPC1	O15118-1.2	T1203I	Pathogenic	0.697
NPC1	O15118-1.2	T1203K	Pathogenic	0.731
NPC1	O15118-1.2	T1203L	Pathogenic	0.704
NPC1	O15118-1.2	T1203M	Pathogenic	0.736
NPC1	O15118-1.2	T1203N	Pathogenic	0.624
NPC1	O15118-1.2	T1203P	Pathogenic	0.736
NPC1	O15118-1.2	T1203Q	Pathogenic	0.756
NPC1	O15118-1.2	T1203R	Pathogenic	0.745
NPC1	O15118-1.2	T1203S	Pathogenic	0.601
NPC1	O15118-1.2	T1203V	Pathogenic	0.629
NPC1	O15118-1.2	T1203W	Pathogenic	0.787
NPC1	O15118-1.2	T1203Y	Pathogenic	0.832
NPC1	O15118-1.2	L1204A	Pathogenic	0.698
NPC1	O15118-1.2	L1204C	Pathogenic	0.72
NPC1	O15118-1.2	L1204D	Pathogenic	0.816
NPC1	O15118-1.2	L1204E	Pathogenic	0.739
NPC1	O15118-1.2	L1204F	Pathogenic	0.647
NPC1	O15118-1.2	L1204G	Pathogenic	0.881
NPC1	O15118-1.2	L1204H	Pathogenic	0.776
NPC1	O15118-1.2	L1204I	Neutral	0.441
NPC1	O15118-1.2	L1204K	Pathogenic	0.625
NPC1	O15118-1.2	L1204M	Neutral	0.411
NPC1	O15118-1.2	L1204N	Pathogenic	0.756
NPC1	O15118-1.2	L1204P	Pathogenic	0.833
NPC1	O15118-1.2	L1204Q	Pathogenic	0.682
NPC1	O15118-1.2	L1204R	Pathogenic	0.642
NPC1	O15118-1.2	L1204S	Pathogenic	0.745
NPC1	O15118-1.2	L1204T	Pathogenic	0.66
NPC1	O15118-1.2	L1204V	Pathogenic	0.534
NPC1	O15118-1.2	L1204W	Pathogenic	0.801
NPC1	O15118-1.2	L1204Y	Pathogenic	0.692
NPC1	O15118-1.2	T1205A	Pathogenic	0.812
NPC1	O15118-1.2	T1205C	Pathogenic	0.819
NPC1	O15118-1.2	T1205D	Pathogenic	0.799
NPC1	O15118-1.2	T1205E	Pathogenic	0.819
NPC1	O15118-1.2	T1205F	Pathogenic	0.863
NPC1	O15118-1.2	T1205G	Pathogenic	0.907
NPC1	O15118-1.2	T1205H	Pathogenic	0.901
NPC1	O15118-1.2	T1205I	Pathogenic	0.799
NPC1	O15118-1.2	T1205K	Pathogenic	0.825
NPC1	O15118-1.2	T1205L	Pathogenic	0.805
NPC1	O15118-1.2	T1205M	Pathogenic	0.828
NPC1	O15118-1.2	T1205N	Pathogenic	0.742
NPC1	O15118-1.2	T1205P	Pathogenic	0.828
NPC1	O15118-1.2	T1205Q	Pathogenic	0.843
NPC1	O15118-1.2	T1205R	Pathogenic	0.835
NPC1	O15118-1.2	T1205S	Pathogenic	0.723
NPC1	O15118-1.2	T1205V	Pathogenic	0.746
NPC1	O15118-1.2	T1205W	Pathogenic	0.865
NPC1	O15118-1.2	T1205Y	Pathogenic	0.896
NPC1	O15118-1.2	K1206A	Pathogenic	0.787
NPC1	O15118-1.2	K1206C	Pathogenic	0.85
NPC1	O15118-1.2	K1206D	Pathogenic	0.82
NPC1	O15118-1.2	K1206E	Pathogenic	0.644
NPC1	O15118-1.2	K1206F	Pathogenic	0.764
NPC1	O15118-1.2	K1206G	Pathogenic	0.871
NPC1	O15118-1.2	K1206H	Pathogenic	0.742
NPC1	O15118-1.2	K1206I	Pathogenic	0.775
NPC1	O15118-1.2	K1206L	Pathogenic	0.708
NPC1	O15118-1.2	K1206M	Pathogenic	0.658
NPC1	O15118-1.2	K1206N	Pathogenic	0.74
NPC1	O15118-1.2	K1206P	Pathogenic	0.737
NPC1	O15118-1.2	K1206Q	Pathogenic	0.605
NPC1	O15118-1.2	K1206R	Pathogenic	0.56
NPC1	O15118-1.2	K1206S	Pathogenic	0.731
NPC1	O15118-1.2	K1206T	Pathogenic	0.762
NPC1	O15118-1.2	K1206V	Pathogenic	0.761
NPC1	O15118-1.2	K1206W	Pathogenic	0.767
NPC1	O15118-1.2	K1206Y	Pathogenic	0.75
NPC1	O15118-1.2	F1207A	Pathogenic	0.759
NPC1	O15118-1.2	F1207C	Pathogenic	0.778
NPC1	O15118-1.2	F1207D	Pathogenic	0.737
NPC1	O15118-1.2	F1207E	Pathogenic	0.724
NPC1	O15118-1.2	F1207G	Pathogenic	0.824
NPC1	O15118-1.2	F1207H	Pathogenic	0.597
NPC1	O15118-1.2	F1207I	Pathogenic	0.626
NPC1	O15118-1.2	F1207K	Pathogenic	0.666
NPC1	O15118-1.2	F1207L	Pathogenic	0.621
NPC1	O15118-1.2	F1207M	Pathogenic	0.583
NPC1	O15118-1.2	F1207N	Pathogenic	0.742
NPC1	O15118-1.2	F1207P	Pathogenic	0.872
NPC1	O15118-1.2	F1207Q	Pathogenic	0.745
NPC1	O15118-1.2	F1207R	Pathogenic	0.682
NPC1	O15118-1.2	F1207S	Pathogenic	0.73
NPC1	O15118-1.2	F1207T	Pathogenic	0.725
NPC1	O15118-1.2	F1207V	Pathogenic	0.697
NPC1	O15118-1.2	F1207W	Pathogenic	0.521
NPC1	O15118-1.2	F1207Y	Neutral	0.281
NPC1	O15118-1.2	G1208A	Neutral	0.477
NPC1	O15118-1.2	G1208C	Pathogenic	0.723
NPC1	O15118-1.2	G1208D	Pathogenic	0.571
NPC1	O15118-1.2	G1208E	Pathogenic	0.695
NPC1	O15118-1.2	G1208F	Pathogenic	0.728
NPC1	O15118-1.2	G1208H	Pathogenic	0.74
NPC1	O15118-1.2	G1208I	Pathogenic	0.786
NPC1	O15118-1.2	G1208K	Pathogenic	0.704
NPC1	O15118-1.2	G1208L	Pathogenic	0.791
NPC1	O15118-1.2	G1208M	Pathogenic	0.751
NPC1	O15118-1.2	G1208N	Neutral	0.497
NPC1	O15118-1.2	G1208P	Pathogenic	0.664
NPC1	O15118-1.2	G1208Q	Pathogenic	0.73
NPC1	O15118-1.2	G1208R	Pathogenic	0.719
NPC1	O15118-1.2	G1208S	Pathogenic	0.509
NPC1	O15118-1.2	G1208T	Pathogenic	0.702
NPC1	O15118-1.2	G1208V	Pathogenic	0.73
NPC1	O15118-1.2	G1208W	Pathogenic	0.649
NPC1	O15118-1.2	G1208Y	Pathogenic	0.785
NPC1	O15118-1.2	G1209A	Pathogenic	0.781
NPC1	O15118-1.2	G1209C	Pathogenic	0.91
NPC1	O15118-1.2	G1209D	Pathogenic	0.839
NPC1	O15118-1.2	G1209E	Pathogenic	0.899
NPC1	O15118-1.2	G1209F	Pathogenic	0.913
NPC1	O15118-1.2	G1209H	Pathogenic	0.918
NPC1	O15118-1.2	G1209I	Pathogenic	0.935
NPC1	O15118-1.2	G1209K	Pathogenic	0.903
NPC1	O15118-1.2	G1209L	Pathogenic	0.937
NPC1	O15118-1.2	G1209M	Pathogenic	0.922
NPC1	O15118-1.2	G1209N	Pathogenic	0.794
NPC1	O15118-1.2	G1209P	Pathogenic	0.885
NPC1	O15118-1.2	G1209Q	Pathogenic	0.913
NPC1	O15118-1.2	G1209R	Pathogenic	0.909
NPC1	O15118-1.2	G1209S	Pathogenic	0.802
NPC1	O15118-1.2	G1209T	Pathogenic	0.902
NPC1	O15118-1.2	G1209V	Pathogenic	0.913
NPC1	O15118-1.2	G1209W	Pathogenic	0.878
NPC1	O15118-1.2	G1209Y	Pathogenic	0.935
NPC1	O15118-1.2	I1210A	Pathogenic	0.77
NPC1	O15118-1.2	I1210C	Pathogenic	0.789
NPC1	O15118-1.2	I1210D	Pathogenic	0.814
NPC1	O15118-1.2	I1210E	Pathogenic	0.804
NPC1	O15118-1.2	I1210F	Pathogenic	0.738
NPC1	O15118-1.2	I1210G	Pathogenic	0.915
NPC1	O15118-1.2	I1210H	Pathogenic	0.834
NPC1	O15118-1.2	I1210K	Pathogenic	0.781
NPC1	O15118-1.2	I1210L	Pathogenic	0.543
NPC1	O15118-1.2	I1210M	Pathogenic	0.599
NPC1	O15118-1.2	I1210N	Pathogenic	0.818
NPC1	O15118-1.2	I1210P	Pathogenic	0.879
NPC1	O15118-1.2	I1210Q	Pathogenic	0.821
NPC1	O15118-1.2	I1210R	Pathogenic	0.793
NPC1	O15118-1.2	I1210S	Pathogenic	0.809
NPC1	O15118-1.2	I1210T	Pathogenic	0.738
NPC1	O15118-1.2	I1210V	Neutral	0.435
NPC1	O15118-1.2	I1210W	Pathogenic	0.902
NPC1	O15118-1.2	I1210Y	Pathogenic	0.766
NPC1	O15118-1.2	V1211A	Neutral	0.192
NPC1	O15118-1.2	V1211C	Neutral	0.281
NPC1	O15118-1.2	V1211D	Neutral	0.314
NPC1	O15118-1.2	V1211E	Neutral	0.234
NPC1	O15118-1.2	V1211F	Neutral	0.271
NPC1	O15118-1.2	V1211G	Neutral	0.434
NPC1	O15118-1.2	V1211H	Neutral	0.38
NPC1	O15118-1.2	V1211I	Neutral	0.069
NPC1	O15118-1.2	V1211K	Neutral	0.241
NPC1	O15118-1.2	V1211L	Neutral	0.142
NPC1	O15118-1.2	V1211M	Neutral	0.162
NPC1	O15118-1.2	V1211N	Neutral	0.319
NPC1	O15118-1.2	V1211P	Neutral	0.339
NPC1	O15118-1.2	V1211Q	Neutral	0.266
NPC1	O15118-1.2	V1211R	Neutral	0.335
NPC1	O15118-1.2	V1211S	Neutral	0.307
NPC1	O15118-1.2	V1211T	Neutral	0.166
NPC1	O15118-1.2	V1211W	Neutral	0.45
NPC1	O15118-1.2	V1211Y	Neutral	0.3
NPC1	O15118-1.2	V1212A	Pathogenic	0.565
NPC1	O15118-1.2	V1212C	Pathogenic	0.681
NPC1	O15118-1.2	V1212D	Pathogenic	0.714
NPC1	O15118-1.2	V1212E	Pathogenic	0.626
NPC1	O15118-1.2	V1212F	Pathogenic	0.671
NPC1	O15118-1.2	V1212G	Pathogenic	0.807
NPC1	O15118-1.2	V1212H	Pathogenic	0.77
NPC1	O15118-1.2	V1212I	Neutral	0.288
NPC1	O15118-1.2	V1212K	Pathogenic	0.635
NPC1	O15118-1.2	V1212L	Neutral	0.476
NPC1	O15118-1.2	V1212M	Pathogenic	0.515
NPC1	O15118-1.2	V1212N	Pathogenic	0.72
NPC1	O15118-1.2	V1212P	Pathogenic	0.737
NPC1	O15118-1.2	V1212Q	Pathogenic	0.664
NPC1	O15118-1.2	V1212R	Pathogenic	0.734
NPC1	O15118-1.2	V1212S	Pathogenic	0.707
NPC1	O15118-1.2	V1212T	Pathogenic	0.522
NPC1	O15118-1.2	V1212W	Pathogenic	0.817
NPC1	O15118-1.2	V1212Y	Pathogenic	0.701
NPC1	O15118-1.2	L1213A	Pathogenic	0.793
NPC1	O15118-1.2	L1213C	Pathogenic	0.81
NPC1	O15118-1.2	L1213D	Pathogenic	0.88
NPC1	O15118-1.2	L1213E	Pathogenic	0.824
NPC1	O15118-1.2	L1213F	Pathogenic	0.752
NPC1	O15118-1.2	L1213G	Pathogenic	0.925
NPC1	O15118-1.2	L1213H	Pathogenic	0.851
NPC1	O15118-1.2	L1213I	Pathogenic	0.567
NPC1	O15118-1.2	L1213K	Pathogenic	0.735
NPC1	O15118-1.2	L1213M	Pathogenic	0.537
NPC1	O15118-1.2	L1213N	Pathogenic	0.837
NPC1	O15118-1.2	L1213P	Pathogenic	0.892
NPC1	O15118-1.2	L1213Q	Pathogenic	0.78
NPC1	O15118-1.2	L1213R	Pathogenic	0.749
NPC1	O15118-1.2	L1213S	Pathogenic	0.829
NPC1	O15118-1.2	L1213T	Pathogenic	0.763
NPC1	O15118-1.2	L1213V	Pathogenic	0.655
NPC1	O15118-1.2	L1213W	Pathogenic	0.87
NPC1	O15118-1.2	L1213Y	Pathogenic	0.789
NPC1	O15118-1.2	A1214C	Neutral	0.462
NPC1	O15118-1.2	A1214D	Pathogenic	0.626
NPC1	O15118-1.2	A1214E	Pathogenic	0.57
NPC1	O15118-1.2	A1214F	Pathogenic	0.657
NPC1	O15118-1.2	A1214G	Neutral	0.493
NPC1	O15118-1.2	A1214H	Pathogenic	0.727
NPC1	O15118-1.2	A1214I	Pathogenic	0.548
NPC1	O15118-1.2	A1214K	Pathogenic	0.58
NPC1	O15118-1.2	A1214L	Pathogenic	0.556
NPC1	O15118-1.2	A1214M	Pathogenic	0.594
NPC1	O15118-1.2	A1214N	Pathogenic	0.646
NPC1	O15118-1.2	A1214P	Pathogenic	0.586
NPC1	O15118-1.2	A1214Q	Pathogenic	0.611
NPC1	O15118-1.2	A1214R	Pathogenic	0.598
NPC1	O15118-1.2	A1214S	Neutral	0.376
NPC1	O15118-1.2	A1214T	Pathogenic	0.524
NPC1	O15118-1.2	A1214V	Neutral	0.471
NPC1	O15118-1.2	A1214W	Pathogenic	0.741
NPC1	O15118-1.2	A1214Y	Pathogenic	0.723
NPC1	O15118-1.2	F1215A	Pathogenic	0.814
NPC1	O15118-1.2	F1215C	Pathogenic	0.83
NPC1	O15118-1.2	F1215D	Pathogenic	0.795
NPC1	O15118-1.2	F1215E	Pathogenic	0.784
NPC1	O15118-1.2	F1215G	Pathogenic	0.867
NPC1	O15118-1.2	F1215H	Pathogenic	0.673
NPC1	O15118-1.2	F1215I	Pathogenic	0.7
NPC1	O15118-1.2	F1215K	Pathogenic	0.734
NPC1	O15118-1.2	F1215L	Pathogenic	0.694
NPC1	O15118-1.2	F1215M	Pathogenic	0.66
NPC1	O15118-1.2	F1215N	Pathogenic	0.799
NPC1	O15118-1.2	F1215P	Pathogenic	0.904
NPC1	O15118-1.2	F1215Q	Pathogenic	0.802
NPC1	O15118-1.2	F1215R	Pathogenic	0.749
NPC1	O15118-1.2	F1215S	Pathogenic	0.79
NPC1	O15118-1.2	F1215T	Pathogenic	0.786
NPC1	O15118-1.2	F1215V	Pathogenic	0.761
NPC1	O15118-1.2	F1215W	Pathogenic	0.602
NPC1	O15118-1.2	F1215Y	Neutral	0.351
NPC1	O15118-1.2	A1216C	Neutral	0.47
NPC1	O15118-1.2	A1216D	Pathogenic	0.633
NPC1	O15118-1.2	A1216E	Pathogenic	0.578
NPC1	O15118-1.2	A1216F	Pathogenic	0.663
NPC1	O15118-1.2	A1216G	Pathogenic	0.5
NPC1	O15118-1.2	A1216H	Pathogenic	0.733
NPC1	O15118-1.2	A1216I	Pathogenic	0.555
NPC1	O15118-1.2	A1216K	Pathogenic	0.588
NPC1	O15118-1.2	A1216L	Pathogenic	0.564
NPC1	O15118-1.2	A1216M	Pathogenic	0.601
NPC1	O15118-1.2	A1216N	Pathogenic	0.653
NPC1	O15118-1.2	A1216P	Pathogenic	0.593
NPC1	O15118-1.2	A1216Q	Pathogenic	0.618
NPC1	O15118-1.2	A1216R	Pathogenic	0.605
NPC1	O15118-1.2	A1216S	Neutral	0.383
NPC1	O15118-1.2	A1216T	Pathogenic	0.532
NPC1	O15118-1.2	A1216V	Neutral	0.479
NPC1	O15118-1.2	A1216W	Pathogenic	0.747
NPC1	O15118-1.2	A1216Y	Pathogenic	0.729
NPC1	O15118-1.2	K1217A	Pathogenic	0.926
NPC1	O15118-1.2	K1217C	Pathogenic	0.951
NPC1	O15118-1.2	K1217D	Pathogenic	0.939
NPC1	O15118-1.2	K1217E	Pathogenic	0.86
NPC1	O15118-1.2	K1217F	Pathogenic	0.917
NPC1	O15118-1.2	K1217G	Pathogenic	0.958
NPC1	O15118-1.2	K1217H	Pathogenic	0.907
NPC1	O15118-1.2	K1217I	Pathogenic	0.921
NPC1	O15118-1.2	K1217L	Pathogenic	0.892
NPC1	O15118-1.2	K1217M	Pathogenic	0.867
NPC1	O15118-1.2	K1217N	Pathogenic	0.906
NPC1	O15118-1.2	K1217P	Pathogenic	0.905
NPC1	O15118-1.2	K1217Q	Pathogenic	0.839
NPC1	O15118-1.2	K1217R	Pathogenic	0.812
NPC1	O15118-1.2	K1217S	Pathogenic	0.902
NPC1	O15118-1.2	K1217T	Pathogenic	0.916
NPC1	O15118-1.2	K1217V	Pathogenic	0.915
NPC1	O15118-1.2	K1217W	Pathogenic	0.918
NPC1	O15118-1.2	K1217Y	Pathogenic	0.911
NPC1	O15118-1.2	S1218A	Pathogenic	0.834
NPC1	O15118-1.2	S1218C	Pathogenic	0.901
NPC1	O15118-1.2	S1218D	Pathogenic	0.875
NPC1	O15118-1.2	S1218E	Pathogenic	0.891
NPC1	O15118-1.2	S1218F	Pathogenic	0.932
NPC1	O15118-1.2	S1218G	Pathogenic	0.902
NPC1	O15118-1.2	S1218H	Pathogenic	0.936
NPC1	O15118-1.2	S1218I	Pathogenic	0.927
NPC1	O15118-1.2	S1218K	Pathogenic	0.894
NPC1	O15118-1.2	S1218L	Pathogenic	0.93
NPC1	O15118-1.2	S1218M	Pathogenic	0.913
NPC1	O15118-1.2	S1218N	Pathogenic	0.838
NPC1	O15118-1.2	S1218P	Pathogenic	0.91
NPC1	O15118-1.2	S1218Q	Pathogenic	0.906
NPC1	O15118-1.2	S1218R	Pathogenic	0.931
NPC1	O15118-1.2	S1218T	Pathogenic	0.848
NPC1	O15118-1.2	S1218V	Pathogenic	0.933
NPC1	O15118-1.2	S1218W	Pathogenic	0.953
NPC1	O15118-1.2	S1218Y	Pathogenic	0.949
NPC1	O15118-1.2	Q1219A	Pathogenic	0.948
NPC1	O15118-1.2	Q1219C	Pathogenic	0.966
NPC1	O15118-1.2	Q1219D	Pathogenic	0.914
NPC1	O15118-1.2	Q1219E	Pathogenic	0.822
NPC1	O15118-1.2	Q1219F	Pathogenic	0.954
NPC1	O15118-1.2	Q1219G	Pathogenic	0.971
NPC1	O15118-1.2	Q1219H	Pathogenic	0.91
NPC1	O15118-1.2	Q1219I	Pathogenic	0.951
NPC1	O15118-1.2	Q1219K	Pathogenic	0.869
NPC1	O15118-1.2	Q1219L	Pathogenic	0.931
NPC1	O15118-1.2	Q1219M	Pathogenic	0.88
NPC1	O15118-1.2	Q1219N	Pathogenic	0.916
NPC1	O15118-1.2	Q1219P	Pathogenic	0.933
NPC1	O15118-1.2	Q1219R	Pathogenic	0.877
NPC1	O15118-1.2	Q1219S	Pathogenic	0.931
NPC1	O15118-1.2	Q1219T	Pathogenic	0.941
NPC1	O15118-1.2	Q1219V	Pathogenic	0.94
NPC1	O15118-1.2	Q1219W	Pathogenic	0.934
NPC1	O15118-1.2	Q1219Y	Pathogenic	0.929
NPC1	O15118-1.2	I1220A	Pathogenic	0.882
NPC1	O15118-1.2	I1220C	Pathogenic	0.893
NPC1	O15118-1.2	I1220D	Pathogenic	0.907
NPC1	O15118-1.2	I1220E	Pathogenic	0.901
NPC1	O15118-1.2	I1220F	Pathogenic	0.863
NPC1	O15118-1.2	I1220G	Pathogenic	0.96
NPC1	O15118-1.2	I1220H	Pathogenic	0.918
NPC1	O15118-1.2	I1220K	Pathogenic	0.888
NPC1	O15118-1.2	I1220L	Pathogenic	0.725
NPC1	O15118-1.2	I1220M	Pathogenic	0.769
NPC1	O15118-1.2	I1220N	Pathogenic	0.909
NPC1	O15118-1.2	I1220P	Pathogenic	0.942
NPC1	O15118-1.2	I1220Q	Pathogenic	0.911
NPC1	O15118-1.2	I1220R	Pathogenic	0.895
NPC1	O15118-1.2	I1220S	Pathogenic	0.904
NPC1	O15118-1.2	I1220T	Pathogenic	0.862
NPC1	O15118-1.2	I1220V	Pathogenic	0.632
NPC1	O15118-1.2	I1220W	Pathogenic	0.954
NPC1	O15118-1.2	I1220Y	Pathogenic	0.879
NPC1	O15118-1.2	F1221A	Pathogenic	0.943
NPC1	O15118-1.2	F1221C	Pathogenic	0.949
NPC1	O15118-1.2	F1221D	Pathogenic	0.937
NPC1	O15118-1.2	F1221E	Pathogenic	0.933
NPC1	O15118-1.2	F1221G	Pathogenic	0.961
NPC1	O15118-1.2	F1221H	Pathogenic	0.887
NPC1	O15118-1.2	F1221I	Pathogenic	0.898
NPC1	O15118-1.2	F1221K	Pathogenic	0.913
NPC1	O15118-1.2	F1221L	Pathogenic	0.896
NPC1	O15118-1.2	F1221M	Pathogenic	0.881
NPC1	O15118-1.2	F1221N	Pathogenic	0.938
NPC1	O15118-1.2	F1221P	Pathogenic	0.973
NPC1	O15118-1.2	F1221Q	Pathogenic	0.939
NPC1	O15118-1.2	F1221R	Pathogenic	0.919
NPC1	O15118-1.2	F1221S	Pathogenic	0.935
NPC1	O15118-1.2	F1221T	Pathogenic	0.933
NPC1	O15118-1.2	F1221V	Pathogenic	0.924
NPC1	O15118-1.2	F1221W	Pathogenic	0.852
NPC1	O15118-1.2	F1221Y	Pathogenic	0.673
NPC1	O15118-1.2	Q1222A	Pathogenic	0.82
NPC1	O15118-1.2	Q1222C	Pathogenic	0.875
NPC1	O15118-1.2	Q1222D	Pathogenic	0.726
NPC1	O15118-1.2	Q1222E	Pathogenic	0.534
NPC1	O15118-1.2	Q1222F	Pathogenic	0.837
NPC1	O15118-1.2	Q1222G	Pathogenic	0.892
NPC1	O15118-1.2	Q1222H	Pathogenic	0.716
NPC1	O15118-1.2	Q1222I	Pathogenic	0.827
NPC1	O15118-1.2	Q1222K	Pathogenic	0.623
NPC1	O15118-1.2	Q1222L	Pathogenic	0.771
NPC1	O15118-1.2	Q1222M	Pathogenic	0.645
NPC1	O15118-1.2	Q1222N	Pathogenic	0.731
NPC1	O15118-1.2	Q1222P	Pathogenic	0.775
NPC1	O15118-1.2	Q1222R	Pathogenic	0.64
NPC1	O15118-1.2	Q1222S	Pathogenic	0.769
NPC1	O15118-1.2	Q1222T	Pathogenic	0.798
NPC1	O15118-1.2	Q1222V	Pathogenic	0.797
NPC1	O15118-1.2	Q1222W	Pathogenic	0.78
NPC1	O15118-1.2	Q1222Y	Pathogenic	0.764
NPC1	O15118-1.2	I1223A	Pathogenic	0.739
NPC1	O15118-1.2	I1223C	Pathogenic	0.759
NPC1	O15118-1.2	I1223D	Pathogenic	0.787
NPC1	O15118-1.2	I1223E	Pathogenic	0.776
NPC1	O15118-1.2	I1223F	Pathogenic	0.704
NPC1	O15118-1.2	I1223G	Pathogenic	0.901
NPC1	O15118-1.2	I1223H	Pathogenic	0.809
NPC1	O15118-1.2	I1223K	Pathogenic	0.751
NPC1	O15118-1.2	I1223L	Pathogenic	0.5
NPC1	O15118-1.2	I1223M	Pathogenic	0.557
NPC1	O15118-1.2	I1223N	Pathogenic	0.791
NPC1	O15118-1.2	I1223P	Pathogenic	0.859
NPC1	O15118-1.2	I1223Q	Pathogenic	0.794
NPC1	O15118-1.2	I1223R	Pathogenic	0.764
NPC1	O15118-1.2	I1223S	Pathogenic	0.782
NPC1	O15118-1.2	I1223T	Pathogenic	0.704
NPC1	O15118-1.2	I1223V	Neutral	0.394
NPC1	O15118-1.2	I1223W	Pathogenic	0.886
NPC1	O15118-1.2	I1223Y	Pathogenic	0.734
NPC1	O15118-1.2	F1224A	Pathogenic	0.956
NPC1	O15118-1.2	F1224C	Pathogenic	0.96
NPC1	O15118-1.2	F1224D	Pathogenic	0.951
NPC1	O15118-1.2	F1224E	Pathogenic	0.948
NPC1	O15118-1.2	F1224G	Pathogenic	0.97
NPC1	O15118-1.2	F1224H	Pathogenic	0.911
NPC1	O15118-1.2	F1224I	Pathogenic	0.921
NPC1	O15118-1.2	F1224K	Pathogenic	0.932
NPC1	O15118-1.2	F1224L	Pathogenic	0.919
NPC1	O15118-1.2	F1224M	Pathogenic	0.906
NPC1	O15118-1.2	F1224N	Pathogenic	0.952
NPC1	O15118-1.2	F1224P	Pathogenic	0.979
NPC1	O15118-1.2	F1224Q	Pathogenic	0.953
NPC1	O15118-1.2	F1224R	Pathogenic	0.937
NPC1	O15118-1.2	F1224S	Pathogenic	0.949
NPC1	O15118-1.2	F1224T	Pathogenic	0.948
NPC1	O15118-1.2	F1224V	Pathogenic	0.941
NPC1	O15118-1.2	F1224W	Pathogenic	0.883
NPC1	O15118-1.2	F1224Y	Pathogenic	0.729
NPC1	O15118-1.2	Y1225A	Pathogenic	0.96
NPC1	O15118-1.2	Y1225C	Pathogenic	0.964
NPC1	O15118-1.2	Y1225D	Pathogenic	0.955
NPC1	O15118-1.2	Y1225E	Pathogenic	0.932
NPC1	O15118-1.2	Y1225F	Pathogenic	0.686
NPC1	O15118-1.2	Y1225G	Pathogenic	0.973
NPC1	O15118-1.2	Y1225H	Pathogenic	0.781
NPC1	O15118-1.2	Y1225I	Pathogenic	0.916
NPC1	O15118-1.2	Y1225K	Pathogenic	0.912
NPC1	O15118-1.2	Y1225L	Pathogenic	0.919
NPC1	O15118-1.2	Y1225M	Pathogenic	0.929
NPC1	O15118-1.2	Y1225N	Pathogenic	0.937
NPC1	O15118-1.2	Y1225P	Pathogenic	0.972
NPC1	O15118-1.2	Y1225Q	Pathogenic	0.912
NPC1	O15118-1.2	Y1225R	Pathogenic	0.912
NPC1	O15118-1.2	Y1225S	Pathogenic	0.954
NPC1	O15118-1.2	Y1225T	Pathogenic	0.953
NPC1	O15118-1.2	Y1225V	Pathogenic	0.937
NPC1	O15118-1.2	Y1225W	Pathogenic	0.753
NPC1	O15118-1.2	F1226A	Pathogenic	0.963
NPC1	O15118-1.2	F1226C	Pathogenic	0.967
NPC1	O15118-1.2	F1226D	Pathogenic	0.959
NPC1	O15118-1.2	F1226E	Pathogenic	0.956
NPC1	O15118-1.2	F1226G	Pathogenic	0.975
NPC1	O15118-1.2	F1226H	Pathogenic	0.925
NPC1	O15118-1.2	F1226I	Pathogenic	0.933
NPC1	O15118-1.2	F1226K	Pathogenic	0.943
NPC1	O15118-1.2	F1226L	Pathogenic	0.932
NPC1	O15118-1.2	F1226M	Pathogenic	0.921
NPC1	O15118-1.2	F1226N	Pathogenic	0.96
NPC1	O15118-1.2	F1226P	Pathogenic	0.983
NPC1	O15118-1.2	F1226Q	Pathogenic	0.961
NPC1	O15118-1.2	F1226R	Pathogenic	0.947
NPC1	O15118-1.2	F1226S	Pathogenic	0.958
NPC1	O15118-1.2	F1226T	Pathogenic	0.957
NPC1	O15118-1.2	F1226V	Pathogenic	0.95
NPC1	O15118-1.2	F1226W	Pathogenic	0.901
NPC1	O15118-1.2	F1226Y	Pathogenic	0.765
NPC1	O15118-1.2	R1227A	Pathogenic	0.957
NPC1	O15118-1.2	R1227C	Pathogenic	0.972
NPC1	O15118-1.2	R1227D	Pathogenic	0.976
NPC1	O15118-1.2	R1227E	Pathogenic	0.942
NPC1	O15118-1.2	R1227F	Pathogenic	0.952
NPC1	O15118-1.2	R1227G	Pathogenic	0.976
NPC1	O15118-1.2	R1227H	Pathogenic	0.922
NPC1	O15118-1.2	R1227I	Pathogenic	0.954
NPC1	O15118-1.2	R1227K	Pathogenic	0.878
NPC1	O15118-1.2	R1227L	Pathogenic	0.936
NPC1	O15118-1.2	R1227M	Pathogenic	0.921
NPC1	O15118-1.2	R1227N	Pathogenic	0.945
NPC1	O15118-1.2	R1227P	Pathogenic	0.962
NPC1	O15118-1.2	R1227Q	Pathogenic	0.903
NPC1	O15118-1.2	R1227S	Pathogenic	0.96
NPC1	O15118-1.2	R1227T	Pathogenic	0.951
NPC1	O15118-1.2	R1227V	Pathogenic	0.966
NPC1	O15118-1.2	R1227W	Pathogenic	0.945
NPC1	O15118-1.2	R1227Y	Pathogenic	0.944
NPC1	O15118-1.2	M1228A	Pathogenic	0.811
NPC1	O15118-1.2	M1228C	Pathogenic	0.827
NPC1	O15118-1.2	M1228D	Pathogenic	0.849
NPC1	O15118-1.2	M1228E	Pathogenic	0.781
NPC1	O15118-1.2	M1228F	Pathogenic	0.714
NPC1	O15118-1.2	M1228G	Pathogenic	0.904
NPC1	O15118-1.2	M1228H	Pathogenic	0.814
NPC1	O15118-1.2	M1228I	Pathogenic	0.612
NPC1	O15118-1.2	M1228K	Pathogenic	0.678
NPC1	O15118-1.2	M1228L	Pathogenic	0.526
NPC1	O15118-1.2	M1228N	Pathogenic	0.796
NPC1	O15118-1.2	M1228P	Pathogenic	0.863
NPC1	O15118-1.2	M1228Q	Pathogenic	0.648
NPC1	O15118-1.2	M1228R	Pathogenic	0.694
NPC1	O15118-1.2	M1228S	Pathogenic	0.787
NPC1	O15118-1.2	M1228T	Pathogenic	0.783
NPC1	O15118-1.2	M1228V	Pathogenic	0.68
NPC1	O15118-1.2	M1228W	Pathogenic	0.788
NPC1	O15118-1.2	M1228Y	Pathogenic	0.807
NPC1	O15118-1.2	Y1229A	Pathogenic	0.833
NPC1	O15118-1.2	Y1229C	Pathogenic	0.846
NPC1	O15118-1.2	Y1229D	Pathogenic	0.816
NPC1	O15118-1.2	Y1229E	Pathogenic	0.739
NPC1	O15118-1.2	Y1229F	Neutral	0.312
NPC1	O15118-1.2	Y1229G	Pathogenic	0.881
NPC1	O15118-1.2	Y1229H	Neutral	0.425
NPC1	O15118-1.2	Y1229I	Pathogenic	0.693
NPC1	O15118-1.2	Y1229K	Pathogenic	0.682
NPC1	O15118-1.2	Y1229L	Pathogenic	0.7
NPC1	O15118-1.2	Y1229M	Pathogenic	0.732
NPC1	O15118-1.2	Y1229N	Pathogenic	0.756
NPC1	O15118-1.2	Y1229P	Pathogenic	0.88
NPC1	O15118-1.2	Y1229Q	Pathogenic	0.682
NPC1	O15118-1.2	Y1229R	Pathogenic	0.683
NPC1	O15118-1.2	Y1229S	Pathogenic	0.811
NPC1	O15118-1.2	Y1229T	Pathogenic	0.807
NPC1	O15118-1.2	Y1229V	Pathogenic	0.755
NPC1	O15118-1.2	Y1229W	Neutral	0.386
NPC1	O15118-1.2	L1230A	Pathogenic	0.674
NPC1	O15118-1.2	L1230C	Pathogenic	0.697
NPC1	O15118-1.2	L1230D	Pathogenic	0.799
NPC1	O15118-1.2	L1230E	Pathogenic	0.717
NPC1	O15118-1.2	L1230F	Pathogenic	0.621
NPC1	O15118-1.2	L1230G	Pathogenic	0.869
NPC1	O15118-1.2	L1230H	Pathogenic	0.756
NPC1	O15118-1.2	L1230I	Neutral	0.414
NPC1	O15118-1.2	L1230K	Pathogenic	0.599
NPC1	O15118-1.2	L1230M	Neutral	0.385
NPC1	O15118-1.2	L1230N	Pathogenic	0.735
NPC1	O15118-1.2	L1230P	Pathogenic	0.817
NPC1	O15118-1.2	L1230Q	Pathogenic	0.657
NPC1	O15118-1.2	L1230R	Pathogenic	0.617
NPC1	O15118-1.2	L1230S	Pathogenic	0.723
NPC1	O15118-1.2	L1230T	Pathogenic	0.634
NPC1	O15118-1.2	L1230V	Pathogenic	0.506
NPC1	O15118-1.2	L1230W	Pathogenic	0.783
NPC1	O15118-1.2	L1230Y	Pathogenic	0.668
NPC1	O15118-1.2	A1231C	Neutral	0.173
NPC1	O15118-1.2	A1231D	Neutral	0.29
NPC1	O15118-1.2	A1231E	Neutral	0.244
NPC1	O15118-1.2	A1231F	Neutral	0.318
NPC1	O15118-1.2	A1231G	Neutral	0.191
NPC1	O15118-1.2	A1231H	Neutral	0.393
NPC1	O15118-1.2	A1231I	Neutral	0.228
NPC1	O15118-1.2	A1231K	Neutral	0.252
NPC1	O15118-1.2	A1231L	Neutral	0.234
NPC1	O15118-1.2	A1231M	Neutral	0.263
NPC1	O15118-1.2	A1231N	Neutral	0.308
NPC1	O15118-1.2	A1231P	Neutral	0.256
NPC1	O15118-1.2	A1231Q	Neutral	0.277
NPC1	O15118-1.2	A1231R	Neutral	0.266
NPC1	O15118-1.2	A1231S	Neutral	0.128
NPC1	O15118-1.2	A1231T	Neutral	0.212
NPC1	O15118-1.2	A1231V	Neutral	0.178
NPC1	O15118-1.2	A1231W	Neutral	0.41
NPC1	O15118-1.2	A1231Y	Neutral	0.389
NPC1	O15118-1.2	M1232A	Pathogenic	0.545
NPC1	O15118-1.2	M1232C	Pathogenic	0.572
NPC1	O15118-1.2	M1232D	Pathogenic	0.611
NPC1	O15118-1.2	M1232E	Neutral	0.5
NPC1	O15118-1.2	M1232F	Neutral	0.411
NPC1	O15118-1.2	M1232G	Pathogenic	0.724
NPC1	O15118-1.2	M1232H	Pathogenic	0.55
NPC1	O15118-1.2	M1232I	Neutral	0.306
NPC1	O15118-1.2	M1232K	Neutral	0.371
NPC1	O15118-1.2	M1232L	Neutral	0.237
NPC1	O15118-1.2	M1232N	Pathogenic	0.522
NPC1	O15118-1.2	M1232P	Pathogenic	0.638
NPC1	O15118-1.2	M1232Q	Neutral	0.34
NPC1	O15118-1.2	M1232R	Neutral	0.388
NPC1	O15118-1.2	M1232S	Pathogenic	0.508
NPC1	O15118-1.2	M1232T	Pathogenic	0.502
NPC1	O15118-1.2	M1232V	Neutral	0.373
NPC1	O15118-1.2	M1232W	Pathogenic	0.51
NPC1	O15118-1.2	M1232Y	Pathogenic	0.539
NPC1	O15118-1.2	V1233A	Pathogenic	0.596
NPC1	O15118-1.2	V1233C	Pathogenic	0.708
NPC1	O15118-1.2	V1233D	Pathogenic	0.74
NPC1	O15118-1.2	V1233E	Pathogenic	0.655
NPC1	O15118-1.2	V1233F	Pathogenic	0.698
NPC1	O15118-1.2	V1233G	Pathogenic	0.826
NPC1	O15118-1.2	V1233H	Pathogenic	0.792
NPC1	O15118-1.2	V1233I	Neutral	0.315
NPC1	O15118-1.2	V1233K	Pathogenic	0.664
NPC1	O15118-1.2	V1233L	Pathogenic	0.508
NPC1	O15118-1.2	V1233M	Pathogenic	0.546
NPC1	O15118-1.2	V1233N	Pathogenic	0.744
NPC1	O15118-1.2	V1233P	Pathogenic	0.761
NPC1	O15118-1.2	V1233Q	Pathogenic	0.692
NPC1	O15118-1.2	V1233R	Pathogenic	0.758
NPC1	O15118-1.2	V1233S	Pathogenic	0.733
NPC1	O15118-1.2	V1233T	Pathogenic	0.554
NPC1	O15118-1.2	V1233W	Pathogenic	0.836
NPC1	O15118-1.2	V1233Y	Pathogenic	0.727
NPC1	O15118-1.2	L1234A	Pathogenic	0.55
NPC1	O15118-1.2	L1234C	Pathogenic	0.577
NPC1	O15118-1.2	L1234D	Pathogenic	0.702
NPC1	O15118-1.2	L1234E	Pathogenic	0.6
NPC1	O15118-1.2	L1234F	Neutral	0.493
NPC1	O15118-1.2	L1234G	Pathogenic	0.798
NPC1	O15118-1.2	L1234H	Pathogenic	0.647
NPC1	O15118-1.2	L1234I	Neutral	0.295
NPC1	O15118-1.2	L1234K	Neutral	0.469
NPC1	O15118-1.2	L1234M	Neutral	0.27
NPC1	O15118-1.2	L1234N	Pathogenic	0.621
NPC1	O15118-1.2	L1234P	Pathogenic	0.725
NPC1	O15118-1.2	L1234Q	Pathogenic	0.532
NPC1	O15118-1.2	L1234R	Neutral	0.488
NPC1	O15118-1.2	L1234S	Pathogenic	0.607
NPC1	O15118-1.2	L1234T	Pathogenic	0.507
NPC1	O15118-1.2	L1234V	Neutral	0.378
NPC1	O15118-1.2	L1234W	Pathogenic	0.681
NPC1	O15118-1.2	L1234Y	Pathogenic	0.544
NPC1	O15118-1.2	L1235A	Neutral	0.3
NPC1	O15118-1.2	L1235C	Neutral	0.324
NPC1	O15118-1.2	L1235D	Neutral	0.452
NPC1	O15118-1.2	L1235E	Neutral	0.345
NPC1	O15118-1.2	L1235F	Neutral	0.254
NPC1	O15118-1.2	L1235G	Pathogenic	0.58
NPC1	O15118-1.2	L1235H	Neutral	0.391
NPC1	O15118-1.2	L1235I	Neutral	0.128
NPC1	O15118-1.2	L1235K	Neutral	0.237
NPC1	O15118-1.2	L1235M	Neutral	0.115
NPC1	O15118-1.2	L1235N	Neutral	0.365
NPC1	O15118-1.2	L1235P	Neutral	0.481
NPC1	O15118-1.2	L1235Q	Neutral	0.285
NPC1	O15118-1.2	L1235R	Neutral	0.25
NPC1	O15118-1.2	L1235S	Neutral	0.352
NPC1	O15118-1.2	L1235T	Neutral	0.265
NPC1	O15118-1.2	L1235V	Neutral	0.176
NPC1	O15118-1.2	L1235W	Neutral	0.428
NPC1	O15118-1.2	L1235Y	Neutral	0.295
NPC1	O15118-1.2	G1236A	Pathogenic	0.783
NPC1	O15118-1.2	G1236C	Pathogenic	0.911
NPC1	O15118-1.2	G1236D	Pathogenic	0.84
NPC1	O15118-1.2	G1236E	Pathogenic	0.9
NPC1	O15118-1.2	G1236F	Pathogenic	0.914
NPC1	O15118-1.2	G1236H	Pathogenic	0.918
NPC1	O15118-1.2	G1236I	Pathogenic	0.935
NPC1	O15118-1.2	G1236K	Pathogenic	0.904
NPC1	O15118-1.2	G1236L	Pathogenic	0.937
NPC1	O15118-1.2	G1236M	Pathogenic	0.922
NPC1	O15118-1.2	G1236N	Pathogenic	0.796
NPC1	O15118-1.2	G1236P	Pathogenic	0.886
NPC1	O15118-1.2	G1236Q	Pathogenic	0.914
NPC1	O15118-1.2	G1236R	Pathogenic	0.91
NPC1	O15118-1.2	G1236S	Pathogenic	0.803
NPC1	O15118-1.2	G1236T	Pathogenic	0.903
NPC1	O15118-1.2	G1236V	Pathogenic	0.914
NPC1	O15118-1.2	G1236W	Pathogenic	0.879
NPC1	O15118-1.2	G1236Y	Pathogenic	0.935
NPC1	O15118-1.2	A1237C	Pathogenic	0.523
NPC1	O15118-1.2	A1237D	Pathogenic	0.682
NPC1	O15118-1.2	A1237E	Pathogenic	0.629
NPC1	O15118-1.2	A1237F	Pathogenic	0.71
NPC1	O15118-1.2	A1237G	Pathogenic	0.554
NPC1	O15118-1.2	A1237H	Pathogenic	0.773
NPC1	O15118-1.2	A1237I	Pathogenic	0.607
NPC1	O15118-1.2	A1237K	Pathogenic	0.639
NPC1	O15118-1.2	A1237L	Pathogenic	0.616
NPC1	O15118-1.2	A1237M	Pathogenic	0.652
NPC1	O15118-1.2	A1237N	Pathogenic	0.7
NPC1	O15118-1.2	A1237P	Pathogenic	0.644
NPC1	O15118-1.2	A1237Q	Pathogenic	0.668
NPC1	O15118-1.2	A1237R	Pathogenic	0.655
NPC1	O15118-1.2	A1237S	Neutral	0.435
NPC1	O15118-1.2	A1237T	Pathogenic	0.585
NPC1	O15118-1.2	A1237V	Pathogenic	0.533
NPC1	O15118-1.2	A1237W	Pathogenic	0.785
NPC1	O15118-1.2	A1237Y	Pathogenic	0.77
NPC1	O15118-1.2	T1238A	Neutral	0.247
NPC1	O15118-1.2	T1238C	Neutral	0.256
NPC1	O15118-1.2	T1238D	Neutral	0.232
NPC1	O15118-1.2	T1238E	Neutral	0.256
NPC1	O15118-1.2	T1238F	Neutral	0.324
NPC1	O15118-1.2	T1238G	Neutral	0.427
NPC1	O15118-1.2	T1238H	Neutral	0.408
NPC1	O15118-1.2	T1238I	Neutral	0.233
NPC1	O15118-1.2	T1238K	Neutral	0.264
NPC1	O15118-1.2	T1238L	Neutral	0.239
NPC1	O15118-1.2	T1238M	Neutral	0.268
NPC1	O15118-1.2	T1238N	Neutral	0.18
NPC1	O15118-1.2	T1238P	Neutral	0.269
NPC1	O15118-1.2	T1238Q	Neutral	0.289
NPC1	O15118-1.2	T1238R	Neutral	0.278
NPC1	O15118-1.2	T1238S	Neutral	0.166
NPC1	O15118-1.2	T1238V	Neutral	0.183
NPC1	O15118-1.2	T1238W	Neutral	0.327
NPC1	O15118-1.2	T1238Y	Neutral	0.395
NPC1	O15118-1.2	H1239A	Pathogenic	0.933
NPC1	O15118-1.2	H1239C	Pathogenic	0.936
NPC1	O15118-1.2	H1239D	Pathogenic	0.866
NPC1	O15118-1.2	H1239E	Pathogenic	0.805
NPC1	O15118-1.2	H1239F	Pathogenic	0.826
NPC1	O15118-1.2	H1239G	Pathogenic	0.941
NPC1	O15118-1.2	H1239I	Pathogenic	0.905
NPC1	O15118-1.2	H1239K	Pathogenic	0.85
NPC1	O15118-1.2	H1239L	Pathogenic	0.908
NPC1	O15118-1.2	H1239M	Pathogenic	0.887
NPC1	O15118-1.2	H1239N	Pathogenic	0.754
NPC1	O15118-1.2	H1239P	Pathogenic	0.914
NPC1	O15118-1.2	H1239Q	Pathogenic	0.821
NPC1	O15118-1.2	H1239R	Pathogenic	0.806
NPC1	O15118-1.2	H1239S	Pathogenic	0.902
NPC1	O15118-1.2	H1239T	Pathogenic	0.924
NPC1	O15118-1.2	H1239V	Pathogenic	0.924
NPC1	O15118-1.2	H1239W	Pathogenic	0.876
NPC1	O15118-1.2	H1239Y	Pathogenic	0.67
NPC1	O15118-1.2	G1240A	Pathogenic	0.761
NPC1	O15118-1.2	G1240C	Pathogenic	0.901
NPC1	O15118-1.2	G1240D	Pathogenic	0.823
NPC1	O15118-1.2	G1240E	Pathogenic	0.888
NPC1	O15118-1.2	G1240F	Pathogenic	0.903
NPC1	O15118-1.2	G1240H	Pathogenic	0.909
NPC1	O15118-1.2	G1240I	Pathogenic	0.927
NPC1	O15118-1.2	G1240K	Pathogenic	0.892
NPC1	O15118-1.2	G1240L	Pathogenic	0.93
NPC1	O15118-1.2	G1240M	Pathogenic	0.913
NPC1	O15118-1.2	G1240N	Pathogenic	0.775
NPC1	O15118-1.2	G1240P	Pathogenic	0.873
NPC1	O15118-1.2	G1240Q	Pathogenic	0.904
NPC1	O15118-1.2	G1240R	Pathogenic	0.899
NPC1	O15118-1.2	G1240S	Pathogenic	0.783
NPC1	O15118-1.2	G1240T	Pathogenic	0.891
NPC1	O15118-1.2	G1240V	Pathogenic	0.904
NPC1	O15118-1.2	G1240W	Pathogenic	0.866
NPC1	O15118-1.2	G1240Y	Pathogenic	0.927
NPC1	O15118-1.2	L1241A	Pathogenic	0.736
NPC1	O15118-1.2	L1241C	Pathogenic	0.757
NPC1	O15118-1.2	L1241D	Pathogenic	0.843
NPC1	O15118-1.2	L1241E	Pathogenic	0.774
NPC1	O15118-1.2	L1241F	Pathogenic	0.689
NPC1	O15118-1.2	L1241G	Pathogenic	0.9
NPC1	O15118-1.2	L1241H	Pathogenic	0.807
NPC1	O15118-1.2	L1241I	Neutral	0.488
NPC1	O15118-1.2	L1241K	Pathogenic	0.669
NPC1	O15118-1.2	L1241M	Neutral	0.458
NPC1	O15118-1.2	L1241N	Pathogenic	0.789
NPC1	O15118-1.2	L1241P	Pathogenic	0.858
NPC1	O15118-1.2	L1241Q	Pathogenic	0.722
NPC1	O15118-1.2	L1241R	Pathogenic	0.685
NPC1	O15118-1.2	L1241S	Pathogenic	0.779
NPC1	O15118-1.2	L1241T	Pathogenic	0.701
NPC1	O15118-1.2	L1241V	Pathogenic	0.581
NPC1	O15118-1.2	L1241W	Pathogenic	0.83
NPC1	O15118-1.2	L1241Y	Pathogenic	0.731
NPC1	O15118-1.2	I1242A	Pathogenic	0.573
NPC1	O15118-1.2	I1242C	Pathogenic	0.599
NPC1	O15118-1.2	I1242D	Pathogenic	0.637
NPC1	O15118-1.2	I1242E	Pathogenic	0.622
NPC1	O15118-1.2	I1242F	Pathogenic	0.53
NPC1	O15118-1.2	I1242G	Pathogenic	0.812
NPC1	O15118-1.2	I1242H	Pathogenic	0.668
NPC1	O15118-1.2	I1242K	Pathogenic	0.588
NPC1	O15118-1.2	I1242L	Neutral	0.322
NPC1	O15118-1.2	I1242M	Neutral	0.374
NPC1	O15118-1.2	I1242N	Pathogenic	0.643
NPC1	O15118-1.2	I1242P	Pathogenic	0.743
NPC1	O15118-1.2	I1242Q	Pathogenic	0.647
NPC1	O15118-1.2	I1242R	Pathogenic	0.606
NPC1	O15118-1.2	I1242S	Pathogenic	0.629
NPC1	O15118-1.2	I1242T	Pathogenic	0.53
NPC1	O15118-1.2	I1242V	Neutral	0.235
NPC1	O15118-1.2	I1242W	Pathogenic	0.787
NPC1	O15118-1.2	I1242Y	Pathogenic	0.567
NPC1	O15118-1.2	F1243A	Pathogenic	0.833
NPC1	O15118-1.2	F1243C	Pathogenic	0.847
NPC1	O15118-1.2	F1243D	Pathogenic	0.816
NPC1	O15118-1.2	F1243E	Pathogenic	0.806
NPC1	O15118-1.2	F1243G	Pathogenic	0.881
NPC1	O15118-1.2	F1243H	Pathogenic	0.701
NPC1	O15118-1.2	F1243I	Pathogenic	0.726
NPC1	O15118-1.2	F1243K	Pathogenic	0.759
NPC1	O15118-1.2	F1243L	Pathogenic	0.722
NPC1	O15118-1.2	F1243M	Pathogenic	0.689
NPC1	O15118-1.2	F1243N	Pathogenic	0.82
NPC1	O15118-1.2	F1243P	Pathogenic	0.915
NPC1	O15118-1.2	F1243Q	Pathogenic	0.822
NPC1	O15118-1.2	F1243R	Pathogenic	0.773
NPC1	O15118-1.2	F1243S	Pathogenic	0.811
NPC1	O15118-1.2	F1243T	Pathogenic	0.807
NPC1	O15118-1.2	F1243V	Pathogenic	0.784
NPC1	O15118-1.2	F1243W	Pathogenic	0.633
NPC1	O15118-1.2	F1243Y	Neutral	0.382
NPC1	O15118-1.2	L1244A	Pathogenic	0.75
NPC1	O15118-1.2	L1244C	Pathogenic	0.77
NPC1	O15118-1.2	L1244D	Pathogenic	0.852
NPC1	O15118-1.2	L1244E	Pathogenic	0.786
NPC1	O15118-1.2	L1244F	Pathogenic	0.704
NPC1	O15118-1.2	L1244G	Pathogenic	0.906
NPC1	O15118-1.2	L1244H	Pathogenic	0.818
NPC1	O15118-1.2	L1244I	Pathogenic	0.506
NPC1	O15118-1.2	L1244K	Pathogenic	0.684
NPC1	O15118-1.2	L1244M	Neutral	0.475
NPC1	O15118-1.2	L1244N	Pathogenic	0.801
NPC1	O15118-1.2	L1244P	Pathogenic	0.866
NPC1	O15118-1.2	L1244Q	Pathogenic	0.736
NPC1	O15118-1.2	L1244R	Pathogenic	0.7
NPC1	O15118-1.2	L1244S	Pathogenic	0.791
NPC1	O15118-1.2	L1244T	Pathogenic	0.716
NPC1	O15118-1.2	L1244V	Pathogenic	0.598
NPC1	O15118-1.2	L1244W	Pathogenic	0.839
NPC1	O15118-1.2	L1244Y	Pathogenic	0.745
NPC1	O15118-1.2	P1245A	Pathogenic	0.847
NPC1	O15118-1.2	P1245C	Pathogenic	0.918
NPC1	O15118-1.2	P1245D	Pathogenic	0.772
NPC1	O15118-1.2	P1245E	Pathogenic	0.798
NPC1	O15118-1.2	P1245F	Pathogenic	0.942
NPC1	O15118-1.2	P1245G	Pathogenic	0.892
NPC1	O15118-1.2	P1245H	Pathogenic	0.888
NPC1	O15118-1.2	P1245I	Pathogenic	0.911
NPC1	O15118-1.2	P1245K	Pathogenic	0.804
NPC1	O15118-1.2	P1245L	Pathogenic	0.914
NPC1	O15118-1.2	P1245M	Pathogenic	0.894
NPC1	O15118-1.2	P1245N	Pathogenic	0.844
NPC1	O15118-1.2	P1245Q	Pathogenic	0.823
NPC1	O15118-1.2	P1245R	Pathogenic	0.867
NPC1	O15118-1.2	P1245S	Pathogenic	0.826
NPC1	O15118-1.2	P1245T	Pathogenic	0.828
NPC1	O15118-1.2	P1245V	Pathogenic	0.883
NPC1	O15118-1.2	P1245W	Pathogenic	0.942
NPC1	O15118-1.2	P1245Y	Pathogenic	0.937
NPC1	O15118-1.2	V1246A	Pathogenic	0.686
NPC1	O15118-1.2	V1246C	Pathogenic	0.782
NPC1	O15118-1.2	V1246D	Pathogenic	0.808
NPC1	O15118-1.2	V1246E	Pathogenic	0.738
NPC1	O15118-1.2	V1246F	Pathogenic	0.774
NPC1	O15118-1.2	V1246G	Pathogenic	0.876
NPC1	O15118-1.2	V1246H	Pathogenic	0.85
NPC1	O15118-1.2	V1246I	Neutral	0.406
NPC1	O15118-1.2	V1246K	Pathogenic	0.746
NPC1	O15118-1.2	V1246L	Pathogenic	0.605
NPC1	O15118-1.2	V1246M	Pathogenic	0.641
NPC1	O15118-1.2	V1246N	Pathogenic	0.812
NPC1	O15118-1.2	V1246P	Pathogenic	0.825
NPC1	O15118-1.2	V1246Q	Pathogenic	0.769
NPC1	O15118-1.2	V1246R	Pathogenic	0.823
NPC1	O15118-1.2	V1246S	Pathogenic	0.803
NPC1	O15118-1.2	V1246T	Pathogenic	0.648
NPC1	O15118-1.2	V1246W	Pathogenic	0.883
NPC1	O15118-1.2	V1246Y	Pathogenic	0.798
NPC1	O15118-1.2	L1247A	Pathogenic	0.656
NPC1	O15118-1.2	L1247C	Pathogenic	0.68
NPC1	O15118-1.2	L1247D	Pathogenic	0.786
NPC1	O15118-1.2	L1247E	Pathogenic	0.7
NPC1	O15118-1.2	L1247F	Pathogenic	0.602
NPC1	O15118-1.2	L1247G	Pathogenic	0.86
NPC1	O15118-1.2	L1247H	Pathogenic	0.741
NPC1	O15118-1.2	L1247I	Neutral	0.394
NPC1	O15118-1.2	L1247K	Pathogenic	0.579
NPC1	O15118-1.2	L1247M	Neutral	0.366
NPC1	O15118-1.2	L1247N	Pathogenic	0.719
NPC1	O15118-1.2	L1247P	Pathogenic	0.804
NPC1	O15118-1.2	L1247Q	Pathogenic	0.639
NPC1	O15118-1.2	L1247R	Pathogenic	0.597
NPC1	O15118-1.2	L1247S	Pathogenic	0.707
NPC1	O15118-1.2	L1247T	Pathogenic	0.615
NPC1	O15118-1.2	L1247V	Neutral	0.486
NPC1	O15118-1.2	L1247W	Pathogenic	0.769
NPC1	O15118-1.2	L1247Y	Pathogenic	0.65
NPC1	O15118-1.2	L1248A	Pathogenic	0.772
NPC1	O15118-1.2	L1248C	Pathogenic	0.791
NPC1	O15118-1.2	L1248D	Pathogenic	0.867
NPC1	O15118-1.2	L1248E	Pathogenic	0.806
NPC1	O15118-1.2	L1248F	Pathogenic	0.729
NPC1	O15118-1.2	L1248G	Pathogenic	0.916
NPC1	O15118-1.2	L1248H	Pathogenic	0.836
NPC1	O15118-1.2	L1248I	Pathogenic	0.537
NPC1	O15118-1.2	L1248K	Pathogenic	0.711
NPC1	O15118-1.2	L1248M	Pathogenic	0.507
NPC1	O15118-1.2	L1248N	Pathogenic	0.82
NPC1	O15118-1.2	L1248P	Pathogenic	0.88
NPC1	O15118-1.2	L1248Q	Pathogenic	0.759
NPC1	O15118-1.2	L1248R	Pathogenic	0.725
NPC1	O15118-1.2	L1248S	Pathogenic	0.811
NPC1	O15118-1.2	L1248T	Pathogenic	0.74
NPC1	O15118-1.2	L1248V	Pathogenic	0.628
NPC1	O15118-1.2	L1248W	Pathogenic	0.856
NPC1	O15118-1.2	L1248Y	Pathogenic	0.768
NPC1	O15118-1.2	S1249A	Pathogenic	0.843
NPC1	O15118-1.2	S1249C	Pathogenic	0.907
NPC1	O15118-1.2	S1249D	Pathogenic	0.882
NPC1	O15118-1.2	S1249E	Pathogenic	0.897
NPC1	O15118-1.2	S1249F	Pathogenic	0.936
NPC1	O15118-1.2	S1249G	Pathogenic	0.908
NPC1	O15118-1.2	S1249H	Pathogenic	0.94
NPC1	O15118-1.2	S1249I	Pathogenic	0.932
NPC1	O15118-1.2	S1249K	Pathogenic	0.901
NPC1	O15118-1.2	S1249L	Pathogenic	0.934
NPC1	O15118-1.2	S1249M	Pathogenic	0.918
NPC1	O15118-1.2	S1249N	Pathogenic	0.847
NPC1	O15118-1.2	S1249P	Pathogenic	0.916
NPC1	O15118-1.2	S1249Q	Pathogenic	0.912
NPC1	O15118-1.2	S1249R	Pathogenic	0.935
NPC1	O15118-1.2	S1249T	Pathogenic	0.856
NPC1	O15118-1.2	S1249V	Pathogenic	0.937
NPC1	O15118-1.2	S1249W	Pathogenic	0.956
NPC1	O15118-1.2	S1249Y	Pathogenic	0.953
NPC1	O15118-1.2	Y1250A	Pathogenic	0.96
NPC1	O15118-1.2	Y1250C	Pathogenic	0.963
NPC1	O15118-1.2	Y1250D	Pathogenic	0.955
NPC1	O15118-1.2	Y1250E	Pathogenic	0.931
NPC1	O15118-1.2	Y1250F	Pathogenic	0.684
NPC1	O15118-1.2	Y1250G	Pathogenic	0.973
NPC1	O15118-1.2	Y1250H	Pathogenic	0.779
NPC1	O15118-1.2	Y1250I	Pathogenic	0.915
NPC1	O15118-1.2	Y1250K	Pathogenic	0.911
NPC1	O15118-1.2	Y1250L	Pathogenic	0.918
NPC1	O15118-1.2	Y1250M	Pathogenic	0.929
NPC1	O15118-1.2	Y1250N	Pathogenic	0.937
NPC1	O15118-1.2	Y1250P	Pathogenic	0.972
NPC1	O15118-1.2	Y1250Q	Pathogenic	0.911
NPC1	O15118-1.2	Y1250R	Pathogenic	0.911
NPC1	O15118-1.2	Y1250S	Pathogenic	0.954
NPC1	O15118-1.2	Y1250T	Pathogenic	0.952
NPC1	O15118-1.2	Y1250V	Pathogenic	0.936
NPC1	O15118-1.2	Y1250W	Pathogenic	0.751
NPC1	O15118-1.2	I1251A	Pathogenic	0.754
NPC1	O15118-1.2	I1251C	Pathogenic	0.773
NPC1	O15118-1.2	I1251D	Pathogenic	0.8
NPC1	O15118-1.2	I1251E	Pathogenic	0.789
NPC1	O15118-1.2	I1251F	Pathogenic	0.72
NPC1	O15118-1.2	I1251G	Pathogenic	0.908
NPC1	O15118-1.2	I1251H	Pathogenic	0.821
NPC1	O15118-1.2	I1251K	Pathogenic	0.765
NPC1	O15118-1.2	I1251L	Pathogenic	0.52
NPC1	O15118-1.2	I1251M	Pathogenic	0.577
NPC1	O15118-1.2	I1251N	Pathogenic	0.804
NPC1	O15118-1.2	I1251P	Pathogenic	0.868
NPC1	O15118-1.2	I1251Q	Pathogenic	0.807
NPC1	O15118-1.2	I1251R	Pathogenic	0.778
NPC1	O15118-1.2	I1251S	Pathogenic	0.795
NPC1	O15118-1.2	I1251T	Pathogenic	0.72
NPC1	O15118-1.2	I1251V	Neutral	0.413
NPC1	O15118-1.2	I1251W	Pathogenic	0.894
NPC1	O15118-1.2	I1251Y	Pathogenic	0.749
NPC1	O15118-1.2	G1252A	Pathogenic	0.914
NPC1	O15118-1.2	G1252C	Pathogenic	0.968
NPC1	O15118-1.2	G1252D	Pathogenic	0.939
NPC1	O15118-1.2	G1252E	Pathogenic	0.964
NPC1	O15118-1.2	G1252F	Pathogenic	0.969
NPC1	O15118-1.2	G1252H	Pathogenic	0.971
NPC1	O15118-1.2	G1252I	Pathogenic	0.977
NPC1	O15118-1.2	G1252K	Pathogenic	0.965
NPC1	O15118-1.2	G1252L	Pathogenic	0.978
NPC1	O15118-1.2	G1252M	Pathogenic	0.972
NPC1	O15118-1.2	G1252N	Pathogenic	0.92
NPC1	O15118-1.2	G1252P	Pathogenic	0.958
NPC1	O15118-1.2	G1252Q	Pathogenic	0.969
NPC1	O15118-1.2	G1252R	Pathogenic	0.967
NPC1	O15118-1.2	G1252S	Pathogenic	0.923
NPC1	O15118-1.2	G1252T	Pathogenic	0.965
NPC1	O15118-1.2	G1252V	Pathogenic	0.969
NPC1	O15118-1.2	G1252W	Pathogenic	0.956
NPC1	O15118-1.2	G1252Y	Pathogenic	0.977
NPC1	O15118-1.2	P1253A	Pathogenic	0.719
NPC1	O15118-1.2	P1253C	Pathogenic	0.838
NPC1	O15118-1.2	P1253D	Pathogenic	0.611
NPC1	O15118-1.2	P1253E	Pathogenic	0.646
NPC1	O15118-1.2	P1253F	Pathogenic	0.882
NPC1	O15118-1.2	P1253G	Pathogenic	0.792
NPC1	O15118-1.2	P1253H	Pathogenic	0.786
NPC1	O15118-1.2	P1253I	Pathogenic	0.826
NPC1	O15118-1.2	P1253K	Pathogenic	0.655
NPC1	O15118-1.2	P1253L	Pathogenic	0.831
NPC1	O15118-1.2	P1253M	Pathogenic	0.796
NPC1	O15118-1.2	P1253N	Pathogenic	0.715
NPC1	O15118-1.2	P1253Q	Pathogenic	0.684
NPC1	O15118-1.2	P1253R	Pathogenic	0.751
NPC1	O15118-1.2	P1253S	Pathogenic	0.688
NPC1	O15118-1.2	P1253T	Pathogenic	0.691
NPC1	O15118-1.2	P1253V	Pathogenic	0.777
NPC1	O15118-1.2	P1253W	Pathogenic	0.884
NPC1	O15118-1.2	P1253Y	Pathogenic	0.874
NPC1	O15118-1.2	S1254A	Neutral	0.179
NPC1	O15118-1.2	S1254C	Neutral	0.282
NPC1	O15118-1.2	S1254D	Neutral	0.233
NPC1	O15118-1.2	S1254E	Neutral	0.261
NPC1	O15118-1.2	S1254F	Neutral	0.373
NPC1	O15118-1.2	S1254G	Neutral	0.285
NPC1	O15118-1.2	S1254H	Neutral	0.388
NPC1	O15118-1.2	S1254I	Neutral	0.357
NPC1	O15118-1.2	S1254K	Neutral	0.269
NPC1	O15118-1.2	S1254L	Neutral	0.364
NPC1	O15118-1.2	S1254M	Neutral	0.313
NPC1	O15118-1.2	S1254N	Neutral	0.183
NPC1	O15118-1.2	S1254P	Neutral	0.306
NPC1	O15118-1.2	S1254Q	Neutral	0.295
NPC1	O15118-1.2	S1254R	Neutral	0.368
NPC1	O15118-1.2	S1254T	Neutral	0.195
NPC1	O15118-1.2	S1254V	Neutral	0.375
NPC1	O15118-1.2	S1254W	Neutral	0.471
NPC1	O15118-1.2	S1254Y	Neutral	0.448
NPC1	O15118-1.2	V1255A	Neutral	0.208
NPC1	O15118-1.2	V1255C	Neutral	0.302
NPC1	O15118-1.2	V1255D	Neutral	0.336
NPC1	O15118-1.2	V1255E	Neutral	0.253
NPC1	O15118-1.2	V1255F	Neutral	0.292
NPC1	O15118-1.2	V1255G	Neutral	0.459
NPC1	O15118-1.2	V1255H	Neutral	0.405
NPC1	O15118-1.2	V1255I	Neutral	0.076
NPC1	O15118-1.2	V1255K	Neutral	0.261
NPC1	O15118-1.2	V1255L	Neutral	0.155
NPC1	O15118-1.2	V1255M	Neutral	0.177
NPC1	O15118-1.2	V1255N	Neutral	0.342
NPC1	O15118-1.2	V1255P	Neutral	0.362
NPC1	O15118-1.2	V1255Q	Neutral	0.286
NPC1	O15118-1.2	V1255R	Neutral	0.358
NPC1	O15118-1.2	V1255S	Neutral	0.329
NPC1	O15118-1.2	V1255T	Neutral	0.181
NPC1	O15118-1.2	V1255W	Neutral	0.476
NPC1	O15118-1.2	V1255Y	Neutral	0.322
NPC1	O15118-1.2	N1256A	Pathogenic	0.809
NPC1	O15118-1.2	N1256C	Pathogenic	0.816
NPC1	O15118-1.2	N1256D	Pathogenic	0.596
NPC1	O15118-1.2	N1256E	Pathogenic	0.704
NPC1	O15118-1.2	N1256F	Pathogenic	0.802
NPC1	O15118-1.2	N1256G	Pathogenic	0.709
NPC1	O15118-1.2	N1256H	Pathogenic	0.575
NPC1	O15118-1.2	N1256I	Pathogenic	0.79
NPC1	O15118-1.2	N1256K	Pathogenic	0.712
NPC1	O15118-1.2	N1256L	Pathogenic	0.796
NPC1	O15118-1.2	N1256M	Pathogenic	0.756
NPC1	O15118-1.2	N1256P	Pathogenic	0.763
NPC1	O15118-1.2	N1256Q	Pathogenic	0.686
NPC1	O15118-1.2	N1256R	Pathogenic	0.727
NPC1	O15118-1.2	N1256S	Pathogenic	0.59
NPC1	O15118-1.2	N1256T	Pathogenic	0.63
NPC1	O15118-1.2	N1256V	Pathogenic	0.803
NPC1	O15118-1.2	N1256W	Pathogenic	0.858
NPC1	O15118-1.2	N1256Y	Pathogenic	0.79
NPC1	O15118-1.2	K1257A	Pathogenic	0.771
NPC1	O15118-1.2	K1257C	Pathogenic	0.839
NPC1	O15118-1.2	K1257D	Pathogenic	0.807
NPC1	O15118-1.2	K1257E	Pathogenic	0.623
NPC1	O15118-1.2	K1257F	Pathogenic	0.747
NPC1	O15118-1.2	K1257G	Pathogenic	0.86
NPC1	O15118-1.2	K1257H	Pathogenic	0.724
NPC1	O15118-1.2	K1257I	Pathogenic	0.759
NPC1	O15118-1.2	K1257L	Pathogenic	0.689
NPC1	O15118-1.2	K1257M	Pathogenic	0.637
NPC1	O15118-1.2	K1257N	Pathogenic	0.722
NPC1	O15118-1.2	K1257P	Pathogenic	0.719
NPC1	O15118-1.2	K1257Q	Pathogenic	0.583
NPC1	O15118-1.2	K1257R	Pathogenic	0.538
NPC1	O15118-1.2	K1257S	Pathogenic	0.713
NPC1	O15118-1.2	K1257T	Pathogenic	0.746
NPC1	O15118-1.2	K1257V	Pathogenic	0.744
NPC1	O15118-1.2	K1257W	Pathogenic	0.75
NPC1	O15118-1.2	K1257Y	Pathogenic	0.733
NPC1	O15118-1.2	A1258C	Neutral	0.401
NPC1	O15118-1.2	A1258D	Pathogenic	0.566
NPC1	O15118-1.2	A1258E	Pathogenic	0.508
NPC1	O15118-1.2	A1258F	Pathogenic	0.598
NPC1	O15118-1.2	A1258G	Neutral	0.43
NPC1	O15118-1.2	A1258H	Pathogenic	0.674
NPC1	O15118-1.2	A1258I	Neutral	0.485
NPC1	O15118-1.2	A1258K	Pathogenic	0.518
NPC1	O15118-1.2	A1258L	Neutral	0.494
NPC1	O15118-1.2	A1258M	Pathogenic	0.533
NPC1	O15118-1.2	A1258N	Pathogenic	0.587
NPC1	O15118-1.2	A1258P	Pathogenic	0.524
NPC1	O15118-1.2	A1258Q	Pathogenic	0.55
NPC1	O15118-1.2	A1258R	Pathogenic	0.537
NPC1	O15118-1.2	A1258S	Neutral	0.319
NPC1	O15118-1.2	A1258T	Neutral	0.462
NPC1	O15118-1.2	A1258V	Neutral	0.41
NPC1	O15118-1.2	A1258W	Pathogenic	0.69
NPC1	O15118-1.2	A1258Y	Pathogenic	0.67
NPC1	O15118-1.2	K1259A	Pathogenic	0.683
NPC1	O15118-1.2	K1259C	Pathogenic	0.768
NPC1	O15118-1.2	K1259D	Pathogenic	0.727
NPC1	O15118-1.2	K1259E	Pathogenic	0.514
NPC1	O15118-1.2	K1259F	Pathogenic	0.654
NPC1	O15118-1.2	K1259G	Pathogenic	0.797
NPC1	O15118-1.2	K1259H	Pathogenic	0.626
NPC1	O15118-1.2	K1259I	Pathogenic	0.667
NPC1	O15118-1.2	K1259L	Pathogenic	0.585
NPC1	O15118-1.2	K1259M	Pathogenic	0.529
NPC1	O15118-1.2	K1259N	Pathogenic	0.624
NPC1	O15118-1.2	K1259P	Pathogenic	0.62
NPC1	O15118-1.2	K1259Q	Neutral	0.471
NPC1	O15118-1.2	K1259R	Neutral	0.426
NPC1	O15118-1.2	K1259S	Pathogenic	0.613
NPC1	O15118-1.2	K1259T	Pathogenic	0.652
NPC1	O15118-1.2	K1259V	Pathogenic	0.65
NPC1	O15118-1.2	K1259W	Pathogenic	0.657
NPC1	O15118-1.2	K1259Y	Pathogenic	0.637
NPC1	O15118-1.2	S1260A	Neutral	0.079
NPC1	O15118-1.2	S1260C	Neutral	0.134
NPC1	O15118-1.2	S1260D	Neutral	0.107
NPC1	O15118-1.2	S1260E	Neutral	0.122
NPC1	O15118-1.2	S1260F	Neutral	0.19
NPC1	O15118-1.2	S1260G	Neutral	0.136
NPC1	O15118-1.2	S1260H	Neutral	0.2
NPC1	O15118-1.2	S1260I	Neutral	0.18
NPC1	O15118-1.2	S1260K	Neutral	0.127
NPC1	O15118-1.2	S1260L	Neutral	0.185
NPC1	O15118-1.2	S1260M	Neutral	0.152
NPC1	O15118-1.2	S1260N	Neutral	0.081
NPC1	O15118-1.2	S1260P	Neutral	0.148
NPC1	O15118-1.2	S1260Q	Neutral	0.142
NPC1	O15118-1.2	S1260R	Neutral	0.187
NPC1	O15118-1.2	S1260T	Neutral	0.087
NPC1	O15118-1.2	S1260V	Neutral	0.192
NPC1	O15118-1.2	S1260W	Neutral	0.26
NPC1	O15118-1.2	S1260Y	Neutral	0.243
NPC1	O15118-1.2	C1261A	Neutral	0.093
NPC1	O15118-1.2	C1261D	Neutral	0.173
NPC1	O15118-1.2	C1261E	Neutral	0.264
NPC1	O15118-1.2	C1261F	Neutral	0.203
NPC1	O15118-1.2	C1261G	Neutral	0.248
NPC1	O15118-1.2	C1261H	Neutral	0.249
NPC1	O15118-1.2	C1261I	Neutral	0.139
NPC1	O15118-1.2	C1261K	Neutral	0.202
NPC1	O15118-1.2	C1261L	Neutral	0.143
NPC1	O15118-1.2	C1261M	Neutral	0.163
NPC1	O15118-1.2	C1261N	Neutral	0.186
NPC1	O15118-1.2	C1261P	Neutral	0.254
NPC1	O15118-1.2	C1261Q	Neutral	0.224
NPC1	O15118-1.2	C1261R	Neutral	0.215
NPC1	O15118-1.2	C1261S	Neutral	0.115
NPC1	O15118-1.2	C1261T	Neutral	0.121
NPC1	O15118-1.2	C1261V	Neutral	0.148
NPC1	O15118-1.2	C1261W	Neutral	0.205
NPC1	O15118-1.2	C1261Y	Neutral	0.255
NPC1	O15118-1.2	A1262C	Neutral	0.193
NPC1	O15118-1.2	A1262D	Neutral	0.318
NPC1	O15118-1.2	A1262E	Neutral	0.27
NPC1	O15118-1.2	A1262F	Neutral	0.347
NPC1	O15118-1.2	A1262G	Neutral	0.213
NPC1	O15118-1.2	A1262H	Neutral	0.426
NPC1	O15118-1.2	A1262I	Neutral	0.252
NPC1	O15118-1.2	A1262K	Neutral	0.278
NPC1	O15118-1.2	A1262L	Neutral	0.259
NPC1	O15118-1.2	A1262M	Neutral	0.29
NPC1	O15118-1.2	A1262N	Neutral	0.337
NPC1	O15118-1.2	A1262P	Neutral	0.282
NPC1	O15118-1.2	A1262Q	Neutral	0.304
NPC1	O15118-1.2	A1262R	Neutral	0.293
NPC1	O15118-1.2	A1262S	Neutral	0.144
NPC1	O15118-1.2	A1262T	Neutral	0.235
NPC1	O15118-1.2	A1262V	Neutral	0.199
NPC1	O15118-1.2	A1262W	Neutral	0.443
NPC1	O15118-1.2	A1262Y	Neutral	0.421
NPC1	O15118-1.2	T1263A	Neutral	0.123
NPC1	O15118-1.2	T1263C	Neutral	0.128
NPC1	O15118-1.2	T1263D	Neutral	0.114
NPC1	O15118-1.2	T1263E	Neutral	0.128
NPC1	O15118-1.2	T1263F	Neutral	0.17
NPC1	O15118-1.2	T1263G	Neutral	0.242
NPC1	O15118-1.2	T1263H	Neutral	0.228
NPC1	O15118-1.2	T1263I	Neutral	0.115
NPC1	O15118-1.2	T1263K	Neutral	0.133
NPC1	O15118-1.2	T1263L	Neutral	0.118
NPC1	O15118-1.2	T1263M	Neutral	0.136
NPC1	O15118-1.2	T1263N	Neutral	0.086
NPC1	O15118-1.2	T1263P	Neutral	0.136
NPC1	O15118-1.2	T1263Q	Neutral	0.148
NPC1	O15118-1.2	T1263R	Neutral	0.141
NPC1	O15118-1.2	T1263S	Neutral	0.078
NPC1	O15118-1.2	T1263V	Neutral	0.087
NPC1	O15118-1.2	T1263W	Neutral	0.172
NPC1	O15118-1.2	T1263Y	Neutral	0.219
NPC1	O15118-1.2	E1264A	Neutral	0.212
NPC1	O15118-1.2	E1264C	Neutral	0.379
NPC1	O15118-1.2	E1264D	Neutral	0.088
NPC1	O15118-1.2	E1264F	Neutral	0.244
NPC1	O15118-1.2	E1264G	Neutral	0.33
NPC1	O15118-1.2	E1264H	Neutral	0.137
NPC1	O15118-1.2	E1264I	Neutral	0.231
NPC1	O15118-1.2	E1264K	Neutral	0.121
NPC1	O15118-1.2	E1264L	Neutral	0.237
NPC1	O15118-1.2	E1264M	Neutral	0.198
NPC1	O15118-1.2	E1264N	Neutral	0.172
NPC1	O15118-1.2	E1264P	Neutral	0.17
NPC1	O15118-1.2	E1264Q	Neutral	0.075
NPC1	O15118-1.2	E1264R	Neutral	0.179
NPC1	O15118-1.2	E1264S	Neutral	0.165
NPC1	O15118-1.2	E1264T	Neutral	0.19
NPC1	O15118-1.2	E1264V	Neutral	0.189
NPC1	O15118-1.2	E1264W	Neutral	0.247
NPC1	O15118-1.2	E1264Y	Neutral	0.231
NPC1	O15118-1.2	E1265A	Neutral	0.309
NPC1	O15118-1.2	E1265C	Pathogenic	0.504
NPC1	O15118-1.2	E1265D	Neutral	0.138
NPC1	O15118-1.2	E1265F	Neutral	0.35
NPC1	O15118-1.2	E1265G	Neutral	0.45
NPC1	O15118-1.2	E1265H	Neutral	0.209
NPC1	O15118-1.2	E1265I	Neutral	0.334
NPC1	O15118-1.2	E1265K	Neutral	0.186
NPC1	O15118-1.2	E1265L	Neutral	0.341
NPC1	O15118-1.2	E1265M	Neutral	0.292
NPC1	O15118-1.2	E1265N	Neutral	0.257
NPC1	O15118-1.2	E1265P	Neutral	0.254
NPC1	O15118-1.2	E1265Q	Neutral	0.118
NPC1	O15118-1.2	E1265R	Neutral	0.266
NPC1	O15118-1.2	E1265S	Neutral	0.248
NPC1	O15118-1.2	E1265T	Neutral	0.28
NPC1	O15118-1.2	E1265V	Neutral	0.279
NPC1	O15118-1.2	E1265W	Neutral	0.353
NPC1	O15118-1.2	E1265Y	Neutral	0.333
NPC1	O15118-1.2	R1266A	Pathogenic	0.545
NPC1	O15118-1.2	R1266C	Pathogenic	0.649
NPC1	O15118-1.2	R1266D	Pathogenic	0.686
NPC1	O15118-1.2	R1266E	Neutral	0.464
NPC1	O15118-1.2	R1266F	Pathogenic	0.513
NPC1	O15118-1.2	R1266G	Pathogenic	0.687
NPC1	O15118-1.2	R1266H	Neutral	0.389
NPC1	O15118-1.2	R1266I	Pathogenic	0.528
NPC1	O15118-1.2	R1266K	Neutral	0.278
NPC1	O15118-1.2	R1266L	Neutral	0.44
NPC1	O15118-1.2	R1266M	Neutral	0.385
NPC1	O15118-1.2	R1266N	Neutral	0.481
NPC1	O15118-1.2	R1266P	Pathogenic	0.573
NPC1	O15118-1.2	R1266Q	Neutral	0.332
NPC1	O15118-1.2	R1266S	Pathogenic	0.565
NPC1	O15118-1.2	R1266T	Pathogenic	0.511
NPC1	O15118-1.2	R1266V	Pathogenic	0.604
NPC1	O15118-1.2	R1266W	Neutral	0.477
NPC1	O15118-1.2	R1266Y	Neutral	0.476
NPC1	O15118-1.2	Y1267A	Neutral	0.291
NPC1	O15118-1.2	Y1267C	Neutral	0.311
NPC1	O15118-1.2	Y1267D	Neutral	0.267
NPC1	O15118-1.2	Y1267E	Neutral	0.189
NPC1	O15118-1.2	Y1267F	Neutral	0.036
NPC1	O15118-1.2	Y1267G	Neutral	0.38
NPC1	O15118-1.2	Y1267H	Neutral	0.057
NPC1	O15118-1.2	Y1267I	Neutral	0.157
NPC1	O15118-1.2	Y1267K	Neutral	0.15
NPC1	O15118-1.2	Y1267L	Neutral	0.161
NPC1	O15118-1.2	Y1267M	Neutral	0.183
NPC1	O15118-1.2	Y1267N	Neutral	0.203
NPC1	O15118-1.2	Y1267P	Neutral	0.376
NPC1	O15118-1.2	Y1267Q	Neutral	0.15
NPC1	O15118-1.2	Y1267R	Neutral	0.15
NPC1	O15118-1.2	Y1267S	Neutral	0.261
NPC1	O15118-1.2	Y1267T	Neutral	0.257
NPC1	O15118-1.2	Y1267V	Neutral	0.202
NPC1	O15118-1.2	Y1267W	Neutral	0.049
NPC1	O15118-1.2	K1268A	Neutral	0.277
NPC1	O15118-1.2	K1268C	Neutral	0.371
NPC1	O15118-1.2	K1268D	Neutral	0.321
NPC1	O15118-1.2	K1268E	Neutral	0.158
NPC1	O15118-1.2	K1268F	Neutral	0.251
NPC1	O15118-1.2	K1268G	Neutral	0.412
NPC1	O15118-1.2	K1268H	Neutral	0.23
NPC1	O15118-1.2	K1268I	Neutral	0.263
NPC1	O15118-1.2	K1268L	Neutral	0.201
NPC1	O15118-1.2	K1268M	Neutral	0.166
NPC1	O15118-1.2	K1268N	Neutral	0.228
NPC1	O15118-1.2	K1268P	Neutral	0.225
NPC1	O15118-1.2	K1268Q	Neutral	0.137
NPC1	O15118-1.2	K1268R	Neutral	0.117
NPC1	O15118-1.2	K1268S	Neutral	0.22
NPC1	O15118-1.2	K1268T	Neutral	0.25
NPC1	O15118-1.2	K1268V	Neutral	0.249
NPC1	O15118-1.2	K1268W	Neutral	0.254
NPC1	O15118-1.2	K1268Y	Neutral	0.238
NPC1	O15118-1.2	G1269A	Pathogenic	0.53
NPC1	O15118-1.2	G1269C	Pathogenic	0.763
NPC1	O15118-1.2	G1269D	Pathogenic	0.622
NPC1	O15118-1.2	G1269E	Pathogenic	0.738
NPC1	O15118-1.2	G1269F	Pathogenic	0.768
NPC1	O15118-1.2	G1269H	Pathogenic	0.779
NPC1	O15118-1.2	G1269I	Pathogenic	0.819
NPC1	O15118-1.2	G1269K	Pathogenic	0.746
NPC1	O15118-1.2	G1269L	Pathogenic	0.824
NPC1	O15118-1.2	G1269M	Pathogenic	0.788
NPC1	O15118-1.2	G1269N	Pathogenic	0.549
NPC1	O15118-1.2	G1269P	Pathogenic	0.71
NPC1	O15118-1.2	G1269Q	Pathogenic	0.769
NPC1	O15118-1.2	G1269R	Pathogenic	0.759
NPC1	O15118-1.2	G1269S	Pathogenic	0.561
NPC1	O15118-1.2	G1269T	Pathogenic	0.744
NPC1	O15118-1.2	G1269V	Pathogenic	0.769
NPC1	O15118-1.2	G1269W	Pathogenic	0.696
NPC1	O15118-1.2	G1269Y	Pathogenic	0.819
NPC1	O15118-1.2	T1270A	Neutral	0.32
NPC1	O15118-1.2	T1270C	Neutral	0.33
NPC1	O15118-1.2	T1270D	Neutral	0.302
NPC1	O15118-1.2	T1270E	Neutral	0.33
NPC1	O15118-1.2	T1270F	Neutral	0.406
NPC1	O15118-1.2	T1270G	Pathogenic	0.516
NPC1	O15118-1.2	T1270H	Neutral	0.497
NPC1	O15118-1.2	T1270I	Neutral	0.302
NPC1	O15118-1.2	T1270K	Neutral	0.339
NPC1	O15118-1.2	T1270L	Neutral	0.31
NPC1	O15118-1.2	T1270M	Neutral	0.344
NPC1	O15118-1.2	T1270N	Neutral	0.238
NPC1	O15118-1.2	T1270P	Neutral	0.344
NPC1	O15118-1.2	T1270Q	Neutral	0.368
NPC1	O15118-1.2	T1270R	Neutral	0.355
NPC1	O15118-1.2	T1270S	Neutral	0.221
NPC1	O15118-1.2	T1270V	Neutral	0.242
NPC1	O15118-1.2	T1270W	Neutral	0.41
NPC1	O15118-1.2	T1270Y	Neutral	0.483
NPC1	O15118-1.2	E1271A	Neutral	0.449
NPC1	O15118-1.2	E1271C	Pathogenic	0.649
NPC1	O15118-1.2	E1271D	Neutral	0.225
NPC1	O15118-1.2	E1271F	Neutral	0.494
NPC1	O15118-1.2	E1271G	Pathogenic	0.598
NPC1	O15118-1.2	E1271H	Neutral	0.325
NPC1	O15118-1.2	E1271I	Neutral	0.476
NPC1	O15118-1.2	E1271K	Neutral	0.294
NPC1	O15118-1.2	E1271L	Neutral	0.485
NPC1	O15118-1.2	E1271M	Neutral	0.428
NPC1	O15118-1.2	E1271N	Neutral	0.386
NPC1	O15118-1.2	E1271P	Neutral	0.382
NPC1	O15118-1.2	E1271Q	Neutral	0.196
NPC1	O15118-1.2	E1271R	Neutral	0.397
NPC1	O15118-1.2	E1271S	Neutral	0.374
NPC1	O15118-1.2	E1271T	Neutral	0.414
NPC1	O15118-1.2	E1271V	Neutral	0.413
NPC1	O15118-1.2	E1271W	Neutral	0.498
NPC1	O15118-1.2	E1271Y	Neutral	0.476
NPC1	O15118-1.2	R1272A	Neutral	0.451
NPC1	O15118-1.2	R1272C	Pathogenic	0.558
NPC1	O15118-1.2	R1272D	Pathogenic	0.599
NPC1	O15118-1.2	R1272E	Neutral	0.372
NPC1	O15118-1.2	R1272F	Neutral	0.418
NPC1	O15118-1.2	R1272G	Pathogenic	0.6
NPC1	O15118-1.2	R1272H	Neutral	0.303
NPC1	O15118-1.2	R1272I	Neutral	0.433
NPC1	O15118-1.2	R1272K	Neutral	0.208
NPC1	O15118-1.2	R1272L	Neutral	0.35
NPC1	O15118-1.2	R1272M	Neutral	0.299
NPC1	O15118-1.2	R1272N	Neutral	0.388
NPC1	O15118-1.2	R1272P	Neutral	0.478
NPC1	O15118-1.2	R1272Q	Neutral	0.254
NPC1	O15118-1.2	R1272S	Neutral	0.47
NPC1	O15118-1.2	R1272T	Neutral	0.416
NPC1	O15118-1.2	R1272V	Pathogenic	0.51
NPC1	O15118-1.2	R1272W	Neutral	0.384
NPC1	O15118-1.2	R1272Y	Neutral	0.383
NPC1	O15118-1.2	E1273A	Neutral	0.42
NPC1	O15118-1.2	E1273C	Pathogenic	0.622
NPC1	O15118-1.2	E1273D	Neutral	0.205
NPC1	O15118-1.2	E1273F	Neutral	0.465
NPC1	O15118-1.2	E1273G	Pathogenic	0.57
NPC1	O15118-1.2	E1273H	Neutral	0.3
NPC1	O15118-1.2	E1273I	Neutral	0.448
NPC1	O15118-1.2	E1273K	Neutral	0.27
NPC1	O15118-1.2	E1273L	Neutral	0.456
NPC1	O15118-1.2	E1273M	Neutral	0.4
NPC1	O15118-1.2	E1273N	Neutral	0.359
NPC1	O15118-1.2	E1273P	Neutral	0.355
NPC1	O15118-1.2	E1273Q	Neutral	0.178
NPC1	O15118-1.2	E1273R	Neutral	0.37
NPC1	O15118-1.2	E1273S	Neutral	0.348
NPC1	O15118-1.2	E1273T	Neutral	0.387
NPC1	O15118-1.2	E1273V	Neutral	0.385
NPC1	O15118-1.2	E1273W	Neutral	0.469
NPC1	O15118-1.2	E1273Y	Neutral	0.447
NPC1	O15118-1.2	R1274A	Neutral	0.346
NPC1	O15118-1.2	R1274C	Neutral	0.45
NPC1	O15118-1.2	R1274D	Neutral	0.491
NPC1	O15118-1.2	R1274E	Neutral	0.277
NPC1	O15118-1.2	R1274F	Neutral	0.317
NPC1	O15118-1.2	R1274G	Neutral	0.492
NPC1	O15118-1.2	R1274H	Neutral	0.219
NPC1	O15118-1.2	R1274I	Neutral	0.331
NPC1	O15118-1.2	R1274K	Neutral	0.145
NPC1	O15118-1.2	R1274L	Neutral	0.258
NPC1	O15118-1.2	R1274M	Neutral	0.216
NPC1	O15118-1.2	R1274N	Neutral	0.29
NPC1	O15118-1.2	R1274P	Neutral	0.372
NPC1	O15118-1.2	R1274Q	Neutral	0.18
NPC1	O15118-1.2	R1274S	Neutral	0.364
NPC1	O15118-1.2	R1274T	Neutral	0.315
NPC1	O15118-1.2	R1274V	Neutral	0.403
NPC1	O15118-1.2	R1274W	Neutral	0.287
NPC1	O15118-1.2	R1274Y	Neutral	0.286
NPC1	O15118-1.2	L1275A	Neutral	0.135
NPC1	O15118-1.2	L1275C	Neutral	0.149
NPC1	O15118-1.2	L1275D	Neutral	0.231
NPC1	O15118-1.2	L1275E	Neutral	0.161
NPC1	O15118-1.2	L1275F	Neutral	0.111
NPC1	O15118-1.2	L1275G	Neutral	0.335
NPC1	O15118-1.2	L1275H	Neutral	0.19
NPC1	O15118-1.2	L1275I	Neutral	0.051
NPC1	O15118-1.2	L1275K	Neutral	0.102
NPC1	O15118-1.2	L1275M	Neutral	0.045
NPC1	O15118-1.2	L1275N	Neutral	0.174
NPC1	O15118-1.2	L1275P	Neutral	0.252
NPC1	O15118-1.2	L1275Q	Neutral	0.127
NPC1	O15118-1.2	L1275R	Neutral	0.109
NPC1	O15118-1.2	L1275S	Neutral	0.165
NPC1	O15118-1.2	L1275T	Neutral	0.116
NPC1	O15118-1.2	L1275V	Neutral	0.072
NPC1	O15118-1.2	L1275W	Neutral	0.215
NPC1	O15118-1.2	L1275Y	Neutral	0.132
NPC1	O15118-1.2	L1276A	Neutral	0.118
NPC1	O15118-1.2	L1276C	Neutral	0.13
NPC1	O15118-1.2	L1276D	Neutral	0.204
NPC1	O15118-1.2	L1276E	Neutral	0.14
NPC1	O15118-1.2	L1276F	Neutral	0.096
NPC1	O15118-1.2	L1276G	Neutral	0.301
NPC1	O15118-1.2	L1276H	Neutral	0.167
NPC1	O15118-1.2	L1276I	Neutral	0.044
NPC1	O15118-1.2	L1276K	Neutral	0.088
NPC1	O15118-1.2	L1276M	Neutral	0.039
NPC1	O15118-1.2	L1276N	Neutral	0.152
NPC1	O15118-1.2	L1276P	Neutral	0.223
NPC1	O15118-1.2	L1276Q	Neutral	0.11
NPC1	O15118-1.2	L1276R	Neutral	0.094
NPC1	O15118-1.2	L1276S	Neutral	0.144
NPC1	O15118-1.2	L1276T	Neutral	0.101
NPC1	O15118-1.2	L1276V	Neutral	0.062
NPC1	O15118-1.2	L1276W	Neutral	0.189
NPC1	O15118-1.2	L1276Y	Neutral	0.115
NPC1	O15118-1.2	N1277A	Neutral	0.09
NPC1	O15118-1.2	N1277C	Neutral	0.094
NPC1	O15118-1.2	N1277D	Neutral	0.033
NPC1	O15118-1.2	N1277E	Neutral	0.053
NPC1	O15118-1.2	N1277F	Neutral	0.087
NPC1	O15118-1.2	N1277G	Neutral	0.054
NPC1	O15118-1.2	N1277H	Neutral	0.031
NPC1	O15118-1.2	N1277I	Neutral	0.081
NPC1	O15118-1.2	N1277K	Neutral	0.055
NPC1	O15118-1.2	N1277L	Neutral	0.084
NPC1	O15118-1.2	N1277M	Neutral	0.068
NPC1	O15118-1.2	N1277P	Neutral	0.07
NPC1	O15118-1.2	N1277Q	Neutral	0.049
NPC1	O15118-1.2	N1277R	Neutral	0.059
NPC1	O15118-1.2	N1277S	Neutral	0.033
NPC1	O15118-1.2	N1277T	Neutral	0.038
NPC1	O15118-1.2	N1277V	Neutral	0.087
NPC1	O15118-1.2	N1277W	Neutral	0.124
NPC1	O15118-1.2	N1277Y	Neutral	0.081
NPC1	O15118-1.2	F1278A	Neutral	0.132
NPC1	O15118-1.2	F1278C	Neutral	0.145
NPC1	O15118-1.2	F1278D	Neutral	0.119
NPC1	O15118-1.2	F1278E	Neutral	0.112
NPC1	O15118-1.2	F1278G	Neutral	0.184
NPC1	O15118-1.2	F1278H	Neutral	0.067
NPC1	O15118-1.2	F1278I	Neutral	0.075
NPC1	O15118-1.2	F1278K	Neutral	0.088
NPC1	O15118-1.2	F1278L	Neutral	0.073
NPC1	O15118-1.2	F1278M	Neutral	0.063
NPC1	O15118-1.2	F1278N	Neutral	0.121
NPC1	O15118-1.2	F1278P	Neutral	0.246
NPC1	O15118-1.2	F1278Q	Neutral	0.123
NPC1	O15118-1.2	F1278R	Neutral	0.094
NPC1	O15118-1.2	F1278S	Neutral	0.115
NPC1	O15118-1.2	F1278T	Neutral	0.113
NPC1	O15118-1.2	F1278V	Neutral	0.1
NPC1	O15118-1.2	F1278W	Neutral	0.05
NPC1	O15118-1.2	F1278Y	Neutral	0.018
RS1	O15537-1.2	M1A	Neutral	0.007
RS1	O15537-1.2	M1C	Neutral	0.019
RS1	O15537-1.2	M1D	Neutral	0.023
RS1	O15537-1.2	M1E	Neutral	0.004
RS1	O15537-1.2	M1F	Neutral	0.001
RS1	O15537-1.2	M1G	Neutral	0.169
RS1	O15537-1.2	M1H	Neutral	0.014
RS1	O15537-1.2	M1I	Neutral	0.0
RS1	O15537-1.2	M1K	Neutral	0.0
RS1	O15537-1.2	M1L	Neutral	0.0
RS1	O15537-1.2	M1N	Neutral	0.005
RS1	O15537-1.2	M1P	Neutral	0.064
RS1	O15537-1.2	M1Q	Neutral	0.0
RS1	O15537-1.2	M1R	Neutral	0.0
RS1	O15537-1.2	M1S	Neutral	0.003
RS1	O15537-1.2	M1T	Neutral	0.004
RS1	O15537-1.2	M1V	Neutral	0.001
RS1	O15537-1.2	M1W	Neutral	0.004
RS1	O15537-1.2	M1Y	Neutral	0.013
RS1	O15537-1.2	S2A	Neutral	0.0
RS1	O15537-1.2	S2C	Neutral	0.0
RS1	O15537-1.2	S2D	Neutral	0.0
RS1	O15537-1.2	S2E	Neutral	0.0
RS1	O15537-1.2	S2F	Neutral	0.001
RS1	O15537-1.2	S2G	Neutral	0.0
RS1	O15537-1.2	S2H	Neutral	0.002
RS1	O15537-1.2	S2I	Neutral	0.0
RS1	O15537-1.2	S2K	Neutral	0.0
RS1	O15537-1.2	S2L	Neutral	0.001
RS1	O15537-1.2	S2M	Neutral	0.0
RS1	O15537-1.2	S2N	Neutral	0.0
RS1	O15537-1.2	S2P	Neutral	0.0
RS1	O15537-1.2	S2Q	Neutral	0.0
RS1	O15537-1.2	S2R	Neutral	0.001
RS1	O15537-1.2	S2T	Neutral	0.0
RS1	O15537-1.2	S2V	Neutral	0.001
RS1	O15537-1.2	S2W	Neutral	0.002
RS1	O15537-1.2	S2Y	Neutral	0.003
RS1	O15537-1.2	R3A	Neutral	0.0
RS1	O15537-1.2	R3C	Neutral	0.003
RS1	O15537-1.2	R3D	Neutral	0.013
RS1	O15537-1.2	R3E	Neutral	0.0
RS1	O15537-1.2	R3F	Neutral	0.0
RS1	O15537-1.2	R3G	Neutral	0.006
RS1	O15537-1.2	R3H	Neutral	0.0
RS1	O15537-1.2	R3I	Neutral	0.0
RS1	O15537-1.2	R3K	Neutral	0.0
RS1	O15537-1.2	R3L	Neutral	0.0
RS1	O15537-1.2	R3M	Neutral	0.0
RS1	O15537-1.2	R3N	Neutral	0.0
RS1	O15537-1.2	R3P	Neutral	0.001
RS1	O15537-1.2	R3Q	Neutral	0.0
RS1	O15537-1.2	R3S	Neutral	0.001
RS1	O15537-1.2	R3T	Neutral	0.0
RS1	O15537-1.2	R3V	Neutral	0.001
RS1	O15537-1.2	R3W	Neutral	0.0
RS1	O15537-1.2	R3Y	Neutral	0.0
RS1	O15537-1.2	K4A	Neutral	0.001
RS1	O15537-1.2	K4C	Neutral	0.005
RS1	O15537-1.2	K4D	Neutral	0.004
RS1	O15537-1.2	K4E	Neutral	0.0
RS1	O15537-1.2	K4F	Neutral	0.0
RS1	O15537-1.2	K4G	Neutral	0.01
RS1	O15537-1.2	K4H	Neutral	0.0
RS1	O15537-1.2	K4I	Neutral	0.001
RS1	O15537-1.2	K4L	Neutral	0.0
RS1	O15537-1.2	K4M	Neutral	0.0
RS1	O15537-1.2	K4N	Neutral	0.0
RS1	O15537-1.2	K4P	Neutral	0.0
RS1	O15537-1.2	K4Q	Neutral	0.0
RS1	O15537-1.2	K4R	Neutral	0.0
RS1	O15537-1.2	K4S	Neutral	0.0
RS1	O15537-1.2	K4T	Neutral	0.0
RS1	O15537-1.2	K4V	Neutral	0.0
RS1	O15537-1.2	K4W	Neutral	0.0
RS1	O15537-1.2	K4Y	Neutral	0.0
RS1	O15537-1.2	I5A	Neutral	0.0
RS1	O15537-1.2	I5C	Neutral	0.0
RS1	O15537-1.2	I5D	Neutral	0.0
RS1	O15537-1.2	I5E	Neutral	0.0
RS1	O15537-1.2	I5F	Neutral	0.0
RS1	O15537-1.2	I5G	Neutral	0.015
RS1	O15537-1.2	I5H	Neutral	0.001
RS1	O15537-1.2	I5K	Neutral	0.0
RS1	O15537-1.2	I5L	Neutral	0.0
RS1	O15537-1.2	I5M	Neutral	0.0
RS1	O15537-1.2	I5N	Neutral	0.0
RS1	O15537-1.2	I5P	Neutral	0.005
RS1	O15537-1.2	I5Q	Neutral	0.001
RS1	O15537-1.2	I5R	Neutral	0.0
RS1	O15537-1.2	I5S	Neutral	0.0
RS1	O15537-1.2	I5T	Neutral	0.0
RS1	O15537-1.2	I5V	Neutral	0.0
RS1	O15537-1.2	I5W	Neutral	0.019
RS1	O15537-1.2	I5Y	Neutral	0.0
RS1	O15537-1.2	E6A	Neutral	0.001
RS1	O15537-1.2	E6C	Neutral	0.042
RS1	O15537-1.2	E6D	Neutral	0.0
RS1	O15537-1.2	E6F	Neutral	0.001
RS1	O15537-1.2	E6G	Neutral	0.013
RS1	O15537-1.2	E6H	Neutral	0.0
RS1	O15537-1.2	E6I	Neutral	0.001
RS1	O15537-1.2	E6K	Neutral	0.0
RS1	O15537-1.2	E6L	Neutral	0.001
RS1	O15537-1.2	E6M	Neutral	0.001
RS1	O15537-1.2	E6N	Neutral	0.0
RS1	O15537-1.2	E6P	Neutral	0.0
RS1	O15537-1.2	E6Q	Neutral	0.0
RS1	O15537-1.2	E6R	Neutral	0.0
RS1	O15537-1.2	E6S	Neutral	0.0
RS1	O15537-1.2	E6T	Neutral	0.001
RS1	O15537-1.2	E6V	Neutral	0.0
RS1	O15537-1.2	E6W	Neutral	0.001
RS1	O15537-1.2	E6Y	Neutral	0.001
RS1	O15537-1.2	G7A	Neutral	0.002
RS1	O15537-1.2	G7C	Neutral	0.169
RS1	O15537-1.2	G7D	Neutral	0.008
RS1	O15537-1.2	G7E	Neutral	0.081
RS1	O15537-1.2	G7F	Neutral	0.08
RS1	O15537-1.2	G7H	Neutral	0.215
RS1	O15537-1.2	G7I	Neutral	0.316
RS1	O15537-1.2	G7K	Neutral	0.062
RS1	O15537-1.2	G7L	Neutral	0.361
RS1	O15537-1.2	G7M	Neutral	0.181
RS1	O15537-1.2	G7N	Neutral	0.002
RS1	O15537-1.2	G7P	Neutral	0.053
RS1	O15537-1.2	G7Q	Neutral	0.178
RS1	O15537-1.2	G7R	Neutral	0.072
RS1	O15537-1.2	G7S	Neutral	0.004
RS1	O15537-1.2	G7T	Neutral	0.128
RS1	O15537-1.2	G7V	Neutral	0.146
RS1	O15537-1.2	G7W	Neutral	0.008
RS1	O15537-1.2	G7Y	Neutral	0.328
RS1	O15537-1.2	F8A	Neutral	0.02
RS1	O15537-1.2	F8C	Neutral	0.055
RS1	O15537-1.2	F8D	Neutral	0.011
RS1	O15537-1.2	F8E	Neutral	0.011
RS1	O15537-1.2	F8G	Neutral	0.088
RS1	O15537-1.2	F8H	Neutral	0.001
RS1	O15537-1.2	F8I	Neutral	0.004
RS1	O15537-1.2	F8K	Neutral	0.004
RS1	O15537-1.2	F8L	Neutral	0.003
RS1	O15537-1.2	F8M	Neutral	0.001
RS1	O15537-1.2	F8N	Neutral	0.014
RS1	O15537-1.2	F8P	Pathogenic	0.574
RS1	O15537-1.2	F8Q	Neutral	0.022
RS1	O15537-1.2	F8R	Neutral	0.004
RS1	O15537-1.2	F8S	Neutral	0.009
RS1	O15537-1.2	F8T	Neutral	0.012
RS1	O15537-1.2	F8V	Neutral	0.011
RS1	O15537-1.2	F8W	Neutral	0.0
RS1	O15537-1.2	F8Y	Neutral	0.0
RS1	O15537-1.2	L9A	Neutral	0.111
RS1	O15537-1.2	L9C	Neutral	0.26
RS1	O15537-1.2	L9D	Pathogenic	0.733
RS1	O15537-1.2	L9E	Neutral	0.297
RS1	O15537-1.2	L9F	Neutral	0.111
RS1	O15537-1.2	L9G	Pathogenic	0.96
RS1	O15537-1.2	L9H	Pathogenic	0.626
RS1	O15537-1.2	L9I	Neutral	0.002
RS1	O15537-1.2	L9K	Neutral	0.03
RS1	O15537-1.2	L9M	Neutral	0.001
RS1	O15537-1.2	L9N	Neutral	0.356
RS1	O15537-1.2	L9P	Pathogenic	0.89
RS1	O15537-1.2	L9Q	Neutral	0.122
RS1	O15537-1.2	L9R	Neutral	0.035
RS1	O15537-1.2	L9S	Neutral	0.27
RS1	O15537-1.2	L9T	Neutral	0.07
RS1	O15537-1.2	L9V	Neutral	0.01
RS1	O15537-1.2	L9W	Pathogenic	0.761
RS1	O15537-1.2	L9Y	Neutral	0.196
RS1	O15537-1.2	L10A	Neutral	0.041
RS1	O15537-1.2	L10C	Neutral	0.108
RS1	O15537-1.2	L10D	Neutral	0.487
RS1	O15537-1.2	L10E	Neutral	0.127
RS1	O15537-1.2	L10F	Neutral	0.041
RS1	O15537-1.2	L10G	Pathogenic	0.892
RS1	O15537-1.2	L10H	Neutral	0.366
RS1	O15537-1.2	L10I	Neutral	0.001
RS1	O15537-1.2	L10K	Neutral	0.011
RS1	O15537-1.2	L10M	Neutral	0.0
RS1	O15537-1.2	L10N	Neutral	0.16
RS1	O15537-1.2	L10P	Pathogenic	0.737
RS1	O15537-1.2	L10Q	Neutral	0.046
RS1	O15537-1.2	L10R	Neutral	0.012
RS1	O15537-1.2	L10S	Neutral	0.113
RS1	O15537-1.2	L10T	Neutral	0.025
RS1	O15537-1.2	L10V	Neutral	0.003
RS1	O15537-1.2	L10W	Pathogenic	0.524
RS1	O15537-1.2	L10Y	Neutral	0.078
RS1	O15537-1.2	L11A	Neutral	0.112
RS1	O15537-1.2	L11C	Neutral	0.263
RS1	O15537-1.2	L11D	Pathogenic	0.737
RS1	O15537-1.2	L11E	Neutral	0.301
RS1	O15537-1.2	L11F	Neutral	0.113
RS1	O15537-1.2	L11G	Pathogenic	0.961
RS1	O15537-1.2	L11H	Pathogenic	0.63
RS1	O15537-1.2	L11I	Neutral	0.003
RS1	O15537-1.2	L11K	Neutral	0.031
RS1	O15537-1.2	L11M	Neutral	0.001
RS1	O15537-1.2	L11N	Neutral	0.36
RS1	O15537-1.2	L11P	Pathogenic	0.892
RS1	O15537-1.2	L11Q	Neutral	0.124
RS1	O15537-1.2	L11R	Neutral	0.036
RS1	O15537-1.2	L11S	Neutral	0.274
RS1	O15537-1.2	L11T	Neutral	0.072
RS1	O15537-1.2	L11V	Neutral	0.01
RS1	O15537-1.2	L11W	Pathogenic	0.765
RS1	O15537-1.2	L11Y	Neutral	0.199
RS1	O15537-1.2	L12A	Neutral	0.422
RS1	O15537-1.2	L12C	Pathogenic	0.673
RS1	O15537-1.2	L12D	Pathogenic	0.942
RS1	O15537-1.2	L12E	Pathogenic	0.713
RS1	O15537-1.2	L12F	Neutral	0.424
RS1	O15537-1.2	L12G	Pathogenic	0.993
RS1	O15537-1.2	L12H	Pathogenic	0.908
RS1	O15537-1.2	L12I	Neutral	0.014
RS1	O15537-1.2	L12K	Neutral	0.154
RS1	O15537-1.2	L12M	Neutral	0.007
RS1	O15537-1.2	L12N	Pathogenic	0.764
RS1	O15537-1.2	L12P	Pathogenic	0.979
RS1	O15537-1.2	L12Q	Neutral	0.448
RS1	O15537-1.2	L12R	Neutral	0.177
RS1	O15537-1.2	L12S	Pathogenic	0.685
RS1	O15537-1.2	L12T	Neutral	0.308
RS1	O15537-1.2	L12V	Neutral	0.056
RS1	O15537-1.2	L12W	Pathogenic	0.949
RS1	O15537-1.2	L12Y	Pathogenic	0.589
RS1	O15537-1.2	L13A	Neutral	0.335
RS1	O15537-1.2	L13C	Pathogenic	0.587
RS1	O15537-1.2	L13D	Pathogenic	0.918
RS1	O15537-1.2	L13E	Pathogenic	0.631
RS1	O15537-1.2	L13F	Neutral	0.336
RS1	O15537-1.2	L13G	Pathogenic	0.99
RS1	O15537-1.2	L13H	Pathogenic	0.871
RS1	O15537-1.2	L13I	Neutral	0.01
RS1	O15537-1.2	L13K	Neutral	0.111
RS1	O15537-1.2	L13M	Neutral	0.005
RS1	O15537-1.2	L13N	Pathogenic	0.691
RS1	O15537-1.2	L13P	Pathogenic	0.97
RS1	O15537-1.2	L13Q	Neutral	0.359
RS1	O15537-1.2	L13R	Neutral	0.129
RS1	O15537-1.2	L13S	Pathogenic	0.6
RS1	O15537-1.2	L13T	Neutral	0.234
RS1	O15537-1.2	L13V	Neutral	0.039
RS1	O15537-1.2	L13W	Pathogenic	0.928
RS1	O15537-1.2	L13Y	Neutral	0.497
RS1	O15537-1.2	F14A	Neutral	0.017
RS1	O15537-1.2	F14C	Neutral	0.046
RS1	O15537-1.2	F14D	Neutral	0.009
RS1	O15537-1.2	F14E	Neutral	0.009
RS1	O15537-1.2	F14G	Neutral	0.074
RS1	O15537-1.2	F14H	Neutral	0.001
RS1	O15537-1.2	F14I	Neutral	0.003
RS1	O15537-1.2	F14K	Neutral	0.003
RS1	O15537-1.2	F14L	Neutral	0.003
RS1	O15537-1.2	F14M	Neutral	0.001
RS1	O15537-1.2	F14N	Neutral	0.012
RS1	O15537-1.2	F14P	Pathogenic	0.528
RS1	O15537-1.2	F14Q	Neutral	0.019
RS1	O15537-1.2	F14R	Neutral	0.004
RS1	O15537-1.2	F14S	Neutral	0.008
RS1	O15537-1.2	F14T	Neutral	0.01
RS1	O15537-1.2	F14V	Neutral	0.009
RS1	O15537-1.2	F14W	Neutral	0.0
RS1	O15537-1.2	F14Y	Neutral	0.0
RS1	O15537-1.2	G15A	Neutral	0.002
RS1	O15537-1.2	G15C	Neutral	0.184
RS1	O15537-1.2	G15D	Neutral	0.009
RS1	O15537-1.2	G15E	Neutral	0.089
RS1	O15537-1.2	G15F	Neutral	0.089
RS1	O15537-1.2	G15H	Neutral	0.233
RS1	O15537-1.2	G15I	Neutral	0.339
RS1	O15537-1.2	G15K	Neutral	0.068
RS1	O15537-1.2	G15L	Neutral	0.386
RS1	O15537-1.2	G15M	Neutral	0.198
RS1	O15537-1.2	G15N	Neutral	0.002
RS1	O15537-1.2	G15P	Neutral	0.059
RS1	O15537-1.2	G15Q	Neutral	0.194
RS1	O15537-1.2	G15R	Neutral	0.079
RS1	O15537-1.2	G15S	Neutral	0.004
RS1	O15537-1.2	G15T	Neutral	0.14
RS1	O15537-1.2	G15V	Neutral	0.16
RS1	O15537-1.2	G15W	Neutral	0.009
RS1	O15537-1.2	G15Y	Neutral	0.352
RS1	O15537-1.2	Y16A	Neutral	0.002
RS1	O15537-1.2	Y16C	Neutral	0.004
RS1	O15537-1.2	Y16D	Neutral	0.001
RS1	O15537-1.2	Y16E	Neutral	0.0
RS1	O15537-1.2	Y16F	Neutral	0.0
RS1	O15537-1.2	Y16G	Neutral	0.008
RS1	O15537-1.2	Y16H	Neutral	0.0
RS1	O15537-1.2	Y16I	Neutral	0.0
RS1	O15537-1.2	Y16K	Neutral	0.0
RS1	O15537-1.2	Y16L	Neutral	0.0
RS1	O15537-1.2	Y16M	Neutral	0.0
RS1	O15537-1.2	Y16N	Neutral	0.0
RS1	O15537-1.2	Y16P	Neutral	0.016
RS1	O15537-1.2	Y16Q	Neutral	0.0
RS1	O15537-1.2	Y16R	Neutral	0.0
RS1	O15537-1.2	Y16S	Neutral	0.001
RS1	O15537-1.2	Y16T	Neutral	0.001
RS1	O15537-1.2	Y16V	Neutral	0.0
RS1	O15537-1.2	Y16W	Neutral	0.0
RS1	O15537-1.2	E17A	Pathogenic	1.0
RS1	O15537-1.2	E17C	Pathogenic	1.0
RS1	O15537-1.2	E17D	Pathogenic	0.996
RS1	O15537-1.2	E17F	Pathogenic	1.0
RS1	O15537-1.2	E17G	Pathogenic	1.0
RS1	O15537-1.2	E17H	Pathogenic	1.0
RS1	O15537-1.2	E17I	Pathogenic	1.0
RS1	O15537-1.2	E17K	Pathogenic	0.999
RS1	O15537-1.2	E17L	Pathogenic	1.0
RS1	O15537-1.2	E17M	Pathogenic	1.0
RS1	O15537-1.2	E17N	Pathogenic	1.0
RS1	O15537-1.2	E17P	Pathogenic	1.0
RS1	O15537-1.2	E17Q	Pathogenic	0.991
RS1	O15537-1.2	E17R	Pathogenic	1.0
RS1	O15537-1.2	E17S	Pathogenic	1.0
RS1	O15537-1.2	E17T	Pathogenic	1.0
RS1	O15537-1.2	E17V	Pathogenic	1.0
RS1	O15537-1.2	E17W	Pathogenic	1.0
RS1	O15537-1.2	E17Y	Pathogenic	1.0
RS1	O15537-1.2	A18C	Neutral	0.092
RS1	O15537-1.2	A18D	Pathogenic	0.673
RS1	O15537-1.2	A18E	Neutral	0.353
RS1	O15537-1.2	A18F	Pathogenic	0.645
RS1	O15537-1.2	A18G	Neutral	0.173
RS1	O15537-1.2	A18H	Pathogenic	0.948
RS1	O15537-1.2	A18I	Neutral	0.188
RS1	O15537-1.2	A18K	Neutral	0.288
RS1	O15537-1.2	A18L	Neutral	0.221
RS1	O15537-1.2	A18M	Neutral	0.417
RS1	O15537-1.2	A18N	Pathogenic	0.756
RS1	O15537-1.2	A18P	Pathogenic	0.539
RS1	O15537-1.2	A18Q	Pathogenic	0.573
RS1	O15537-1.2	A18R	Neutral	0.324
RS1	O15537-1.2	A18S	Neutral	0.024
RS1	O15537-1.2	A18T	Neutral	0.279
RS1	O15537-1.2	A18V	Neutral	0.079
RS1	O15537-1.2	A18W	Pathogenic	0.878
RS1	O15537-1.2	A18Y	Pathogenic	0.91
RS1	O15537-1.2	T19A	Neutral	0.02
RS1	O15537-1.2	T19C	Neutral	0.025
RS1	O15537-1.2	T19D	Neutral	0.013
RS1	O15537-1.2	T19E	Neutral	0.021
RS1	O15537-1.2	T19F	Neutral	0.054
RS1	O15537-1.2	T19G	Neutral	0.426
RS1	O15537-1.2	T19H	Neutral	0.415
RS1	O15537-1.2	T19I	Neutral	0.007
RS1	O15537-1.2	T19K	Neutral	0.015
RS1	O15537-1.2	T19L	Neutral	0.009
RS1	O15537-1.2	T19M	Neutral	0.022
RS1	O15537-1.2	T19N	Neutral	0.003
RS1	O15537-1.2	T19P	Neutral	0.039
RS1	O15537-1.2	T19Q	Neutral	0.049
RS1	O15537-1.2	T19R	Neutral	0.018
RS1	O15537-1.2	T19S	Neutral	0.002
RS1	O15537-1.2	T19V	Neutral	0.003
RS1	O15537-1.2	T19W	Neutral	0.034
RS1	O15537-1.2	T19Y	Neutral	0.244
RS1	O15537-1.2	L20A	Pathogenic	0.864
RS1	O15537-1.2	L20C	Pathogenic	0.947
RS1	O15537-1.2	L20D	Pathogenic	0.993
RS1	O15537-1.2	L20E	Pathogenic	0.956
RS1	O15537-1.2	L20F	Pathogenic	0.865
RS1	O15537-1.2	L20G	Pathogenic	0.999
RS1	O15537-1.2	L20H	Pathogenic	0.988
RS1	O15537-1.2	L20I	Neutral	0.113
RS1	O15537-1.2	L20K	Pathogenic	0.613
RS1	O15537-1.2	L20M	Neutral	0.058
RS1	O15537-1.2	L20N	Pathogenic	0.966
RS1	O15537-1.2	L20P	Pathogenic	0.998
RS1	O15537-1.2	L20Q	Pathogenic	0.876
RS1	O15537-1.2	L20R	Pathogenic	0.652
RS1	O15537-1.2	L20S	Pathogenic	0.95
RS1	O15537-1.2	L20T	Pathogenic	0.795
RS1	O15537-1.2	L20V	Neutral	0.341
RS1	O15537-1.2	L20W	Pathogenic	0.994
RS1	O15537-1.2	L20Y	Pathogenic	0.926
RS1	O15537-1.2	G21A	Neutral	0.119
RS1	O15537-1.2	G21C	Pathogenic	0.927
RS1	O15537-1.2	G21D	Neutral	0.335
RS1	O15537-1.2	G21E	Pathogenic	0.847
RS1	O15537-1.2	G21F	Pathogenic	0.845
RS1	O15537-1.2	G21H	Pathogenic	0.945
RS1	O15537-1.2	G21I	Pathogenic	0.967
RS1	O15537-1.2	G21K	Pathogenic	0.804
RS1	O15537-1.2	G21L	Pathogenic	0.973
RS1	O15537-1.2	G21M	Pathogenic	0.933
RS1	O15537-1.2	G21N	Neutral	0.105
RS1	O15537-1.2	G21P	Pathogenic	0.779
RS1	O15537-1.2	G21Q	Pathogenic	0.931
RS1	O15537-1.2	G21R	Pathogenic	0.829
RS1	O15537-1.2	G21S	Neutral	0.201
RS1	O15537-1.2	G21T	Pathogenic	0.902
RS1	O15537-1.2	G21V	Pathogenic	0.914
RS1	O15537-1.2	G21W	Neutral	0.344
RS1	O15537-1.2	G21Y	Pathogenic	0.968
RS1	O15537-1.2	L22A	Neutral	0.394
RS1	O15537-1.2	L22C	Pathogenic	0.647
RS1	O15537-1.2	L22D	Pathogenic	0.935
RS1	O15537-1.2	L22E	Pathogenic	0.688
RS1	O15537-1.2	L22F	Neutral	0.395
RS1	O15537-1.2	L22G	Pathogenic	0.992
RS1	O15537-1.2	L22H	Pathogenic	0.897
RS1	O15537-1.2	L22I	Neutral	0.013
RS1	O15537-1.2	L22K	Neutral	0.139
RS1	O15537-1.2	L22M	Neutral	0.006
RS1	O15537-1.2	L22N	Pathogenic	0.743
RS1	O15537-1.2	L22P	Pathogenic	0.977
RS1	O15537-1.2	L22Q	Neutral	0.42
RS1	O15537-1.2	L22R	Neutral	0.161
RS1	O15537-1.2	L22S	Pathogenic	0.659
RS1	O15537-1.2	L22T	Neutral	0.283
RS1	O15537-1.2	L22V	Neutral	0.05
RS1	O15537-1.2	L22W	Pathogenic	0.943
RS1	O15537-1.2	L22Y	Pathogenic	0.561
RS1	O15537-1.2	S23A	Neutral	0.014
RS1	O15537-1.2	S23C	Neutral	0.15
RS1	O15537-1.2	S23D	Neutral	0.049
RS1	O15537-1.2	S23E	Neutral	0.081
RS1	O15537-1.2	S23F	Neutral	0.328
RS1	O15537-1.2	S23G	Neutral	0.185
RS1	O15537-1.2	S23H	Pathogenic	0.604
RS1	O15537-1.2	S23I	Neutral	0.286
RS1	O15537-1.2	S23K	Neutral	0.062
RS1	O15537-1.2	S23L	Neutral	0.329
RS1	O15537-1.2	S23M	Neutral	0.161
RS1	O15537-1.2	S23N	Neutral	0.012
RS1	O15537-1.2	S23P	Neutral	0.239
RS1	O15537-1.2	S23Q	Neutral	0.178
RS1	O15537-1.2	S23R	Neutral	0.333
RS1	O15537-1.2	S23T	Neutral	0.019
RS1	O15537-1.2	S23V	Neutral	0.487
RS1	O15537-1.2	S23W	Pathogenic	0.659
RS1	O15537-1.2	S23Y	Pathogenic	0.731
RS1	O15537-1.2	S24A	Neutral	0.0
RS1	O15537-1.2	S24C	Neutral	0.002
RS1	O15537-1.2	S24D	Neutral	0.001
RS1	O15537-1.2	S24E	Neutral	0.001
RS1	O15537-1.2	S24F	Neutral	0.007
RS1	O15537-1.2	S24G	Neutral	0.003
RS1	O15537-1.2	S24H	Neutral	0.02
RS1	O15537-1.2	S24I	Neutral	0.005
RS1	O15537-1.2	S24K	Neutral	0.001
RS1	O15537-1.2	S24L	Neutral	0.007
RS1	O15537-1.2	S24M	Neutral	0.003
RS1	O15537-1.2	S24N	Neutral	0.0
RS1	O15537-1.2	S24P	Neutral	0.004
RS1	O15537-1.2	S24Q	Neutral	0.003
RS1	O15537-1.2	S24R	Neutral	0.007
RS1	O15537-1.2	S24T	Neutral	0.0
RS1	O15537-1.2	S24V	Neutral	0.013
RS1	O15537-1.2	S24W	Neutral	0.026
RS1	O15537-1.2	S24Y	Neutral	0.036
RS1	O15537-1.2	T25A	Neutral	0.002
RS1	O15537-1.2	T25C	Neutral	0.003
RS1	O15537-1.2	T25D	Neutral	0.001
RS1	O15537-1.2	T25E	Neutral	0.002
RS1	O15537-1.2	T25F	Neutral	0.006
RS1	O15537-1.2	T25G	Neutral	0.076
RS1	O15537-1.2	T25H	Neutral	0.073
RS1	O15537-1.2	T25I	Neutral	0.001
RS1	O15537-1.2	T25K	Neutral	0.002
RS1	O15537-1.2	T25L	Neutral	0.001
RS1	O15537-1.2	T25M	Neutral	0.003
RS1	O15537-1.2	T25N	Neutral	0.0
RS1	O15537-1.2	T25P	Neutral	0.004
RS1	O15537-1.2	T25Q	Neutral	0.006
RS1	O15537-1.2	T25R	Neutral	0.002
RS1	O15537-1.2	T25S	Neutral	0.0
RS1	O15537-1.2	T25V	Neutral	0.0
RS1	O15537-1.2	T25W	Neutral	0.004
RS1	O15537-1.2	T25Y	Neutral	0.034
RS1	O15537-1.2	E26A	Neutral	0.0
RS1	O15537-1.2	E26C	Neutral	0.008
RS1	O15537-1.2	E26D	Neutral	0.0
RS1	O15537-1.2	E26F	Neutral	0.0
RS1	O15537-1.2	E26G	Neutral	0.002
RS1	O15537-1.2	E26H	Neutral	0.0
RS1	O15537-1.2	E26I	Neutral	0.0
RS1	O15537-1.2	E26K	Neutral	0.0
RS1	O15537-1.2	E26L	Neutral	0.0
RS1	O15537-1.2	E26M	Neutral	0.0
RS1	O15537-1.2	E26N	Neutral	0.0
RS1	O15537-1.2	E26P	Neutral	0.0
RS1	O15537-1.2	E26Q	Neutral	0.0
RS1	O15537-1.2	E26R	Neutral	0.0
RS1	O15537-1.2	E26S	Neutral	0.0
RS1	O15537-1.2	E26T	Neutral	0.0
RS1	O15537-1.2	E26V	Neutral	0.0
RS1	O15537-1.2	E26W	Neutral	0.0
RS1	O15537-1.2	E26Y	Neutral	0.0
RS1	O15537-1.2	D27A	Neutral	0.026
RS1	O15537-1.2	D27C	Neutral	0.033
RS1	O15537-1.2	D27E	Neutral	0.0
RS1	O15537-1.2	D27F	Neutral	0.013
RS1	O15537-1.2	D27G	Neutral	0.01
RS1	O15537-1.2	D27H	Neutral	0.006
RS1	O15537-1.2	D27I	Neutral	0.01
RS1	O15537-1.2	D27K	Neutral	0.03
RS1	O15537-1.2	D27L	Neutral	0.076
RS1	O15537-1.2	D27M	Neutral	0.031
RS1	O15537-1.2	D27N	Neutral	0.0
RS1	O15537-1.2	D27P	Neutral	0.001
RS1	O15537-1.2	D27Q	Neutral	0.002
RS1	O15537-1.2	D27R	Neutral	0.189
RS1	O15537-1.2	D27S	Neutral	0.001
RS1	O15537-1.2	D27T	Neutral	0.003
RS1	O15537-1.2	D27V	Neutral	0.024
RS1	O15537-1.2	D27W	Neutral	0.048
RS1	O15537-1.2	D27Y	Neutral	0.066
RS1	O15537-1.2	E28A	Neutral	0.003
RS1	O15537-1.2	E28C	Neutral	0.132
RS1	O15537-1.2	E28D	Neutral	0.0
RS1	O15537-1.2	E28F	Neutral	0.005
RS1	O15537-1.2	E28G	Neutral	0.043
RS1	O15537-1.2	E28H	Neutral	0.0
RS1	O15537-1.2	E28I	Neutral	0.004
RS1	O15537-1.2	E28K	Neutral	0.0
RS1	O15537-1.2	E28L	Neutral	0.005
RS1	O15537-1.2	E28M	Neutral	0.002
RS1	O15537-1.2	E28N	Neutral	0.002
RS1	O15537-1.2	E28P	Neutral	0.001
RS1	O15537-1.2	E28Q	Neutral	0.0
RS1	O15537-1.2	E28R	Neutral	0.001
RS1	O15537-1.2	E28S	Neutral	0.001
RS1	O15537-1.2	E28T	Neutral	0.002
RS1	O15537-1.2	E28V	Neutral	0.002
RS1	O15537-1.2	E28W	Neutral	0.003
RS1	O15537-1.2	E28Y	Neutral	0.004
RS1	O15537-1.2	G29A	Neutral	0.0
RS1	O15537-1.2	G29C	Neutral	0.0
RS1	O15537-1.2	G29D	Neutral	0.0
RS1	O15537-1.2	G29E	Neutral	0.0
RS1	O15537-1.2	G29F	Neutral	0.0
RS1	O15537-1.2	G29H	Neutral	0.001
RS1	O15537-1.2	G29I	Neutral	0.001
RS1	O15537-1.2	G29K	Neutral	0.0
RS1	O15537-1.2	G29L	Neutral	0.001
RS1	O15537-1.2	G29M	Neutral	0.0
RS1	O15537-1.2	G29N	Neutral	0.0
RS1	O15537-1.2	G29P	Neutral	0.0
RS1	O15537-1.2	G29Q	Neutral	0.0
RS1	O15537-1.2	G29R	Neutral	0.0
RS1	O15537-1.2	G29S	Neutral	0.0
RS1	O15537-1.2	G29T	Neutral	0.0
RS1	O15537-1.2	G29V	Neutral	0.0
RS1	O15537-1.2	G29W	Neutral	0.0
RS1	O15537-1.2	G29Y	Neutral	0.001
RS1	O15537-1.2	E30A	Neutral	0.0
RS1	O15537-1.2	E30C	Neutral	0.002
RS1	O15537-1.2	E30D	Neutral	0.0
RS1	O15537-1.2	E30F	Neutral	0.0
RS1	O15537-1.2	E30G	Neutral	0.001
RS1	O15537-1.2	E30H	Neutral	0.0
RS1	O15537-1.2	E30I	Neutral	0.0
RS1	O15537-1.2	E30K	Neutral	0.0
RS1	O15537-1.2	E30L	Neutral	0.0
RS1	O15537-1.2	E30M	Neutral	0.0
RS1	O15537-1.2	E30N	Neutral	0.0
RS1	O15537-1.2	E30P	Neutral	0.0
RS1	O15537-1.2	E30Q	Neutral	0.0
RS1	O15537-1.2	E30R	Neutral	0.0
RS1	O15537-1.2	E30S	Neutral	0.0
RS1	O15537-1.2	E30T	Neutral	0.0
RS1	O15537-1.2	E30V	Neutral	0.0
RS1	O15537-1.2	E30W	Neutral	0.0
RS1	O15537-1.2	E30Y	Neutral	0.0
RS1	O15537-1.2	D31A	Neutral	0.021
RS1	O15537-1.2	D31C	Neutral	0.027
RS1	O15537-1.2	D31E	Neutral	0.0
RS1	O15537-1.2	D31F	Neutral	0.01
RS1	O15537-1.2	D31G	Neutral	0.008
RS1	O15537-1.2	D31H	Neutral	0.005
RS1	O15537-1.2	D31I	Neutral	0.008
RS1	O15537-1.2	D31K	Neutral	0.024
RS1	O15537-1.2	D31L	Neutral	0.063
RS1	O15537-1.2	D31M	Neutral	0.026
RS1	O15537-1.2	D31N	Neutral	0.0
RS1	O15537-1.2	D31P	Neutral	0.001
RS1	O15537-1.2	D31Q	Neutral	0.001
RS1	O15537-1.2	D31R	Neutral	0.16
RS1	O15537-1.2	D31S	Neutral	0.001
RS1	O15537-1.2	D31T	Neutral	0.003
RS1	O15537-1.2	D31V	Neutral	0.02
RS1	O15537-1.2	D31W	Neutral	0.039
RS1	O15537-1.2	D31Y	Neutral	0.055
RS1	O15537-1.2	P32A	Neutral	0.0
RS1	O15537-1.2	P32C	Neutral	0.001
RS1	O15537-1.2	P32D	Neutral	0.0
RS1	O15537-1.2	P32E	Neutral	0.0
RS1	O15537-1.2	P32F	Neutral	0.002
RS1	O15537-1.2	P32G	Neutral	0.0
RS1	O15537-1.2	P32H	Neutral	0.0
RS1	O15537-1.2	P32I	Neutral	0.0
RS1	O15537-1.2	P32K	Neutral	0.0
RS1	O15537-1.2	P32L	Neutral	0.0
RS1	O15537-1.2	P32M	Neutral	0.0
RS1	O15537-1.2	P32N	Neutral	0.0
RS1	O15537-1.2	P32Q	Neutral	0.0
RS1	O15537-1.2	P32R	Neutral	0.0
RS1	O15537-1.2	P32S	Neutral	0.0
RS1	O15537-1.2	P32T	Neutral	0.0
RS1	O15537-1.2	P32V	Neutral	0.0
RS1	O15537-1.2	P32W	Neutral	0.001
RS1	O15537-1.2	P32Y	Neutral	0.002
RS1	O15537-1.2	W33A	Pathogenic	0.999
RS1	O15537-1.2	W33C	Pathogenic	0.998
RS1	O15537-1.2	W33D	Pathogenic	0.998
RS1	O15537-1.2	W33E	Pathogenic	0.987
RS1	O15537-1.2	W33F	Pathogenic	0.78
RS1	O15537-1.2	W33G	Pathogenic	0.991
RS1	O15537-1.2	W33H	Pathogenic	0.979
RS1	O15537-1.2	W33I	Pathogenic	1.0
RS1	O15537-1.2	W33K	Pathogenic	0.963
RS1	O15537-1.2	W33L	Pathogenic	0.999
RS1	O15537-1.2	W33M	Pathogenic	0.983
RS1	O15537-1.2	W33N	Pathogenic	0.998
RS1	O15537-1.2	W33P	Pathogenic	1.0
RS1	O15537-1.2	W33Q	Pathogenic	0.961
RS1	O15537-1.2	W33R	Pathogenic	0.953
RS1	O15537-1.2	W33S	Pathogenic	0.998
RS1	O15537-1.2	W33T	Pathogenic	0.989
RS1	O15537-1.2	W33V	Pathogenic	1.0
RS1	O15537-1.2	W33Y	Neutral	0.09
RS1	O15537-1.2	Y34A	Neutral	0.0
RS1	O15537-1.2	Y34C	Neutral	0.001
RS1	O15537-1.2	Y34D	Neutral	0.0
RS1	O15537-1.2	Y34E	Neutral	0.0
RS1	O15537-1.2	Y34F	Neutral	0.0
RS1	O15537-1.2	Y34G	Neutral	0.002
RS1	O15537-1.2	Y34H	Neutral	0.0
RS1	O15537-1.2	Y34I	Neutral	0.0
RS1	O15537-1.2	Y34K	Neutral	0.0
RS1	O15537-1.2	Y34L	Neutral	0.0
RS1	O15537-1.2	Y34M	Neutral	0.0
RS1	O15537-1.2	Y34N	Neutral	0.0
RS1	O15537-1.2	Y34P	Neutral	0.004
RS1	O15537-1.2	Y34Q	Neutral	0.0
RS1	O15537-1.2	Y34R	Neutral	0.0
RS1	O15537-1.2	Y34S	Neutral	0.0
RS1	O15537-1.2	Y34T	Neutral	0.0
RS1	O15537-1.2	Y34V	Neutral	0.0
RS1	O15537-1.2	Y34W	Neutral	0.0
RS1	O15537-1.2	Q35A	Neutral	0.0
RS1	O15537-1.2	Q35C	Neutral	0.001
RS1	O15537-1.2	Q35D	Neutral	0.0
RS1	O15537-1.2	Q35E	Neutral	0.0
RS1	O15537-1.2	Q35F	Neutral	0.0
RS1	O15537-1.2	Q35G	Neutral	0.001
RS1	O15537-1.2	Q35H	Neutral	0.0
RS1	O15537-1.2	Q35I	Neutral	0.0
RS1	O15537-1.2	Q35K	Neutral	0.0
RS1	O15537-1.2	Q35L	Neutral	0.0
RS1	O15537-1.2	Q35M	Neutral	0.0
RS1	O15537-1.2	Q35N	Neutral	0.0
RS1	O15537-1.2	Q35P	Neutral	0.0
RS1	O15537-1.2	Q35R	Neutral	0.0
RS1	O15537-1.2	Q35S	Neutral	0.0
RS1	O15537-1.2	Q35T	Neutral	0.0
RS1	O15537-1.2	Q35V	Neutral	0.0
RS1	O15537-1.2	Q35W	Neutral	0.0
RS1	O15537-1.2	Q35Y	Neutral	0.0
RS1	O15537-1.2	K36A	Pathogenic	0.896
RS1	O15537-1.2	K36C	Pathogenic	0.986
RS1	O15537-1.2	K36D	Pathogenic	0.98
RS1	O15537-1.2	K36E	Neutral	0.415
RS1	O15537-1.2	K36F	Pathogenic	0.873
RS1	O15537-1.2	K36G	Pathogenic	0.993
RS1	O15537-1.2	K36H	Pathogenic	0.849
RS1	O15537-1.2	K36I	Pathogenic	0.888
RS1	O15537-1.2	K36L	Pathogenic	0.601
RS1	O15537-1.2	K36M	Neutral	0.371
RS1	O15537-1.2	K36N	Pathogenic	0.838
RS1	O15537-1.2	K36P	Pathogenic	0.731
RS1	O15537-1.2	K36Q	Neutral	0.224
RS1	O15537-1.2	K36R	Neutral	0.149
RS1	O15537-1.2	K36S	Pathogenic	0.707
RS1	O15537-1.2	K36T	Pathogenic	0.866
RS1	O15537-1.2	K36V	Pathogenic	0.839
RS1	O15537-1.2	K36W	Pathogenic	0.81
RS1	O15537-1.2	K36Y	Pathogenic	0.857
RS1	O15537-1.2	A37C	Neutral	0.03
RS1	O15537-1.2	A37D	Neutral	0.385
RS1	O15537-1.2	A37E	Neutral	0.143
RS1	O15537-1.2	A37F	Neutral	0.356
RS1	O15537-1.2	A37G	Neutral	0.06
RS1	O15537-1.2	A37H	Pathogenic	0.848
RS1	O15537-1.2	A37I	Neutral	0.066
RS1	O15537-1.2	A37K	Neutral	0.11
RS1	O15537-1.2	A37L	Neutral	0.08
RS1	O15537-1.2	A37M	Neutral	0.179
RS1	O15537-1.2	A37N	Neutral	0.485
RS1	O15537-1.2	A37P	Neutral	0.263
RS1	O15537-1.2	A37Q	Neutral	0.29
RS1	O15537-1.2	A37R	Neutral	0.128
RS1	O15537-1.2	A37S	Neutral	0.008
RS1	O15537-1.2	A37T	Neutral	0.105
RS1	O15537-1.2	A37V	Neutral	0.025
RS1	O15537-1.2	A37W	Pathogenic	0.687
RS1	O15537-1.2	A37Y	Pathogenic	0.756
RS1	O15537-1.2	C38A	Pathogenic	0.832
RS1	O15537-1.2	C38D	Pathogenic	0.992
RS1	O15537-1.2	C38E	Pathogenic	0.999
RS1	O15537-1.2	C38F	Pathogenic	0.996
RS1	O15537-1.2	C38G	Pathogenic	0.999
RS1	O15537-1.2	C38H	Pathogenic	0.999
RS1	O15537-1.2	C38I	Pathogenic	0.969
RS1	O15537-1.2	C38K	Pathogenic	0.994
RS1	O15537-1.2	C38L	Pathogenic	0.975
RS1	O15537-1.2	C38M	Pathogenic	0.99
RS1	O15537-1.2	C38N	Pathogenic	0.995
RS1	O15537-1.2	C38P	Pathogenic	1.0
RS1	O15537-1.2	C38Q	Pathogenic	0.998
RS1	O15537-1.2	C38R	Pathogenic	0.995
RS1	O15537-1.2	C38S	Pathogenic	0.936
RS1	O15537-1.2	C38T	Pathogenic	0.96
RS1	O15537-1.2	C38V	Pathogenic	0.987
RS1	O15537-1.2	C38W	Pathogenic	0.994
RS1	O15537-1.2	C38Y	Pathogenic	0.999
RS1	O15537-1.2	K39A	Neutral	0.125
RS1	O15537-1.2	K39C	Pathogenic	0.539
RS1	O15537-1.2	K39D	Neutral	0.452
RS1	O15537-1.2	K39E	Neutral	0.012
RS1	O15537-1.2	K39F	Neutral	0.102
RS1	O15537-1.2	K39G	Pathogenic	0.691
RS1	O15537-1.2	K39H	Neutral	0.085
RS1	O15537-1.2	K39I	Neutral	0.115
RS1	O15537-1.2	K39L	Neutral	0.024
RS1	O15537-1.2	K39M	Neutral	0.01
RS1	O15537-1.2	K39N	Neutral	0.079
RS1	O15537-1.2	K39P	Neutral	0.043
RS1	O15537-1.2	K39Q	Neutral	0.005
RS1	O15537-1.2	K39R	Neutral	0.003
RS1	O15537-1.2	K39S	Neutral	0.038
RS1	O15537-1.2	K39T	Neutral	0.096
RS1	O15537-1.2	K39V	Neutral	0.079
RS1	O15537-1.2	K39W	Neutral	0.065
RS1	O15537-1.2	K39Y	Neutral	0.09
RS1	O15537-1.2	C40A	Pathogenic	1.0
RS1	O15537-1.2	C40D	Pathogenic	1.0
RS1	O15537-1.2	C40E	Pathogenic	1.0
RS1	O15537-1.2	C40F	Pathogenic	1.0
RS1	O15537-1.2	C40G	Pathogenic	1.0
RS1	O15537-1.2	C40H	Pathogenic	1.0
RS1	O15537-1.2	C40I	Pathogenic	1.0
RS1	O15537-1.2	C40K	Pathogenic	1.0
RS1	O15537-1.2	C40L	Pathogenic	1.0
RS1	O15537-1.2	C40M	Pathogenic	1.0
RS1	O15537-1.2	C40N	Pathogenic	1.0
RS1	O15537-1.2	C40P	Pathogenic	1.0
RS1	O15537-1.2	C40Q	Pathogenic	1.0
RS1	O15537-1.2	C40R	Pathogenic	1.0
RS1	O15537-1.2	C40S	Pathogenic	1.0
RS1	O15537-1.2	C40T	Pathogenic	1.0
RS1	O15537-1.2	C40V	Pathogenic	1.0
RS1	O15537-1.2	C40W	Pathogenic	1.0
RS1	O15537-1.2	C40Y	Pathogenic	1.0
RS1	O15537-1.2	D41A	Pathogenic	0.761
RS1	O15537-1.2	D41C	Pathogenic	0.802
RS1	O15537-1.2	D41E	Neutral	0.011
RS1	O15537-1.2	D41F	Pathogenic	0.6
RS1	O15537-1.2	D41G	Pathogenic	0.547
RS1	O15537-1.2	D41H	Neutral	0.422
RS1	O15537-1.2	D41I	Pathogenic	0.552
RS1	O15537-1.2	D41K	Pathogenic	0.784
RS1	O15537-1.2	D41L	Pathogenic	0.907
RS1	O15537-1.2	D41M	Pathogenic	0.792
RS1	O15537-1.2	D41N	Neutral	0.051
RS1	O15537-1.2	D41P	Neutral	0.134
RS1	O15537-1.2	D41Q	Neutral	0.176
RS1	O15537-1.2	D41R	Pathogenic	0.965
RS1	O15537-1.2	D41S	Neutral	0.121
RS1	O15537-1.2	D41T	Neutral	0.281
RS1	O15537-1.2	D41V	Pathogenic	0.746
RS1	O15537-1.2	D41W	Pathogenic	0.856
RS1	O15537-1.2	D41Y	Pathogenic	0.894
RS1	O15537-1.2	C42A	Pathogenic	0.912
RS1	O15537-1.2	C42D	Pathogenic	0.996
RS1	O15537-1.2	C42E	Pathogenic	1.0
RS1	O15537-1.2	C42F	Pathogenic	0.998
RS1	O15537-1.2	C42G	Pathogenic	0.999
RS1	O15537-1.2	C42H	Pathogenic	1.0
RS1	O15537-1.2	C42I	Pathogenic	0.985
RS1	O15537-1.2	C42K	Pathogenic	0.997
RS1	O15537-1.2	C42L	Pathogenic	0.988
RS1	O15537-1.2	C42M	Pathogenic	0.995
RS1	O15537-1.2	C42N	Pathogenic	0.998
RS1	O15537-1.2	C42P	Pathogenic	1.0
RS1	O15537-1.2	C42Q	Pathogenic	0.999
RS1	O15537-1.2	C42R	Pathogenic	0.997
RS1	O15537-1.2	C42S	Pathogenic	0.968
RS1	O15537-1.2	C42T	Pathogenic	0.98
RS1	O15537-1.2	C42V	Pathogenic	0.994
RS1	O15537-1.2	C42W	Pathogenic	0.997
RS1	O15537-1.2	C42Y	Pathogenic	1.0
RS1	O15537-1.2	Q43A	Neutral	0.039
RS1	O15537-1.2	Q43C	Neutral	0.249
RS1	O15537-1.2	Q43D	Neutral	0.004
RS1	O15537-1.2	Q43E	Neutral	0.0
RS1	O15537-1.2	Q43F	Neutral	0.057
RS1	O15537-1.2	Q43G	Neutral	0.388
RS1	O15537-1.2	Q43H	Neutral	0.005
RS1	O15537-1.2	Q43I	Neutral	0.048
RS1	O15537-1.2	Q43K	Neutral	0.0
RS1	O15537-1.2	Q43L	Neutral	0.009
RS1	O15537-1.2	Q43M	Neutral	0.001
RS1	O15537-1.2	Q43N	Neutral	0.005
RS1	O15537-1.2	Q43P	Neutral	0.013
RS1	O15537-1.2	Q43R	Neutral	0.0
RS1	O15537-1.2	Q43S	Neutral	0.011
RS1	O15537-1.2	Q43T	Neutral	0.029
RS1	O15537-1.2	Q43V	Neutral	0.024
RS1	O15537-1.2	Q43W	Neutral	0.006
RS1	O15537-1.2	Q43Y	Neutral	0.008
RS1	O15537-1.2	G44A	Neutral	0.005
RS1	O15537-1.2	G44C	Neutral	0.308
RS1	O15537-1.2	G44D	Neutral	0.017
RS1	O15537-1.2	G44E	Neutral	0.162
RS1	O15537-1.2	G44F	Neutral	0.161
RS1	O15537-1.2	G44H	Neutral	0.376
RS1	O15537-1.2	G44I	Pathogenic	0.504
RS1	O15537-1.2	G44K	Neutral	0.126
RS1	O15537-1.2	G44L	Pathogenic	0.554
RS1	O15537-1.2	G44M	Neutral	0.327
RS1	O15537-1.2	G44N	Neutral	0.004
RS1	O15537-1.2	G44P	Neutral	0.11
RS1	O15537-1.2	G44Q	Neutral	0.322
RS1	O15537-1.2	G44R	Neutral	0.146
RS1	O15537-1.2	G44S	Neutral	0.009
RS1	O15537-1.2	G44T	Neutral	0.243
RS1	O15537-1.2	G44V	Neutral	0.273
RS1	O15537-1.2	G44W	Neutral	0.018
RS1	O15537-1.2	G44Y	Pathogenic	0.518
RS1	O15537-1.2	G45A	Neutral	0.0
RS1	O15537-1.2	G45C	Neutral	0.005
RS1	O15537-1.2	G45D	Neutral	0.0
RS1	O15537-1.2	G45E	Neutral	0.002
RS1	O15537-1.2	G45F	Neutral	0.002
RS1	O15537-1.2	G45H	Neutral	0.007
RS1	O15537-1.2	G45I	Neutral	0.012
RS1	O15537-1.2	G45K	Neutral	0.002
RS1	O15537-1.2	G45L	Neutral	0.015
RS1	O15537-1.2	G45M	Neutral	0.006
RS1	O15537-1.2	G45N	Neutral	0.0
RS1	O15537-1.2	G45P	Neutral	0.001
RS1	O15537-1.2	G45Q	Neutral	0.006
RS1	O15537-1.2	G45R	Neutral	0.002
RS1	O15537-1.2	G45S	Neutral	0.0
RS1	O15537-1.2	G45T	Neutral	0.004
RS1	O15537-1.2	G45V	Neutral	0.005
RS1	O15537-1.2	G45W	Neutral	0.0
RS1	O15537-1.2	G45Y	Neutral	0.013
RS1	O15537-1.2	P46A	Neutral	0.001
RS1	O15537-1.2	P46C	Neutral	0.022
RS1	O15537-1.2	P46D	Neutral	0.0
RS1	O15537-1.2	P46E	Neutral	0.0
RS1	O15537-1.2	P46F	Neutral	0.053
RS1	O15537-1.2	P46G	Neutral	0.003
RS1	O15537-1.2	P46H	Neutral	0.003
RS1	O15537-1.2	P46I	Neutral	0.007
RS1	O15537-1.2	P46K	Neutral	0.0
RS1	O15537-1.2	P46L	Neutral	0.009
RS1	O15537-1.2	P46M	Neutral	0.003
RS1	O15537-1.2	P46N	Neutral	0.0
RS1	O15537-1.2	P46Q	Neutral	0.0
RS1	O15537-1.2	P46R	Neutral	0.0
RS1	O15537-1.2	P46S	Neutral	0.0
RS1	O15537-1.2	P46T	Neutral	0.0
RS1	O15537-1.2	P46V	Neutral	0.003
RS1	O15537-1.2	P46W	Neutral	0.033
RS1	O15537-1.2	P46Y	Neutral	0.046
RS1	O15537-1.2	N47A	Neutral	0.05
RS1	O15537-1.2	N47C	Neutral	0.063
RS1	O15537-1.2	N47D	Neutral	0.001
RS1	O15537-1.2	N47E	Neutral	0.006
RS1	O15537-1.2	N47F	Neutral	0.021
RS1	O15537-1.2	N47G	Neutral	0.003
RS1	O15537-1.2	N47H	Neutral	0.0
RS1	O15537-1.2	N47I	Neutral	0.017
RS1	O15537-1.2	N47K	Neutral	0.004
RS1	O15537-1.2	N47L	Neutral	0.021
RS1	O15537-1.2	N47M	Neutral	0.008
RS1	O15537-1.2	N47P	Neutral	0.016
RS1	O15537-1.2	N47Q	Neutral	0.003
RS1	O15537-1.2	N47R	Neutral	0.005
RS1	O15537-1.2	N47S	Neutral	0.0
RS1	O15537-1.2	N47T	Neutral	0.001
RS1	O15537-1.2	N47V	Neutral	0.04
RS1	O15537-1.2	N47W	Neutral	0.078
RS1	O15537-1.2	N47Y	Neutral	0.018
RS1	O15537-1.2	A48C	Neutral	0.0
RS1	O15537-1.2	A48D	Neutral	0.005
RS1	O15537-1.2	A48E	Neutral	0.001
RS1	O15537-1.2	A48F	Neutral	0.004
RS1	O15537-1.2	A48G	Neutral	0.001
RS1	O15537-1.2	A48H	Neutral	0.043
RS1	O15537-1.2	A48I	Neutral	0.001
RS1	O15537-1.2	A48K	Neutral	0.001
RS1	O15537-1.2	A48L	Neutral	0.001
RS1	O15537-1.2	A48M	Neutral	0.002
RS1	O15537-1.2	A48N	Neutral	0.008
RS1	O15537-1.2	A48P	Neutral	0.003
RS1	O15537-1.2	A48Q	Neutral	0.003
RS1	O15537-1.2	A48R	Neutral	0.001
RS1	O15537-1.2	A48S	Neutral	0.0
RS1	O15537-1.2	A48T	Neutral	0.001
RS1	O15537-1.2	A48V	Neutral	0.0
RS1	O15537-1.2	A48W	Neutral	0.017
RS1	O15537-1.2	A48Y	Neutral	0.024
RS1	O15537-1.2	L49A	Neutral	0.0
RS1	O15537-1.2	L49C	Neutral	0.0
RS1	O15537-1.2	L49D	Neutral	0.001
RS1	O15537-1.2	L49E	Neutral	0.0
RS1	O15537-1.2	L49F	Neutral	0.0
RS1	O15537-1.2	L49G	Neutral	0.005
RS1	O15537-1.2	L49H	Neutral	0.0
RS1	O15537-1.2	L49I	Neutral	0.0
RS1	O15537-1.2	L49K	Neutral	0.0
RS1	O15537-1.2	L49M	Neutral	0.0
RS1	O15537-1.2	L49N	Neutral	0.0
RS1	O15537-1.2	L49P	Neutral	0.002
RS1	O15537-1.2	L49Q	Neutral	0.0
RS1	O15537-1.2	L49R	Neutral	0.0
RS1	O15537-1.2	L49S	Neutral	0.0
RS1	O15537-1.2	L49T	Neutral	0.0
RS1	O15537-1.2	L49V	Neutral	0.0
RS1	O15537-1.2	L49W	Neutral	0.001
RS1	O15537-1.2	L49Y	Neutral	0.0
RS1	O15537-1.2	W50A	Neutral	0.012
RS1	O15537-1.2	W50C	Neutral	0.006
RS1	O15537-1.2	W50D	Neutral	0.007
RS1	O15537-1.2	W50E	Neutral	0.001
RS1	O15537-1.2	W50F	Neutral	0.0
RS1	O15537-1.2	W50G	Neutral	0.001
RS1	O15537-1.2	W50H	Neutral	0.001
RS1	O15537-1.2	W50I	Neutral	0.092
RS1	O15537-1.2	W50K	Neutral	0.0
RS1	O15537-1.2	W50L	Neutral	0.013
RS1	O15537-1.2	W50M	Neutral	0.001
RS1	O15537-1.2	W50N	Neutral	0.009
RS1	O15537-1.2	W50P	Neutral	0.114
RS1	O15537-1.2	W50Q	Neutral	0.0
RS1	O15537-1.2	W50R	Neutral	0.0
RS1	O15537-1.2	W50S	Neutral	0.006
RS1	O15537-1.2	W50T	Neutral	0.001
RS1	O15537-1.2	W50V	Neutral	0.041
RS1	O15537-1.2	W50Y	Neutral	0.0
RS1	O15537-1.2	S51A	Neutral	0.004
RS1	O15537-1.2	S51C	Neutral	0.05
RS1	O15537-1.2	S51D	Neutral	0.015
RS1	O15537-1.2	S51E	Neutral	0.026
RS1	O15537-1.2	S51F	Neutral	0.128
RS1	O15537-1.2	S51G	Neutral	0.064
RS1	O15537-1.2	S51H	Neutral	0.315
RS1	O15537-1.2	S51I	Neutral	0.108
RS1	O15537-1.2	S51K	Neutral	0.019
RS1	O15537-1.2	S51L	Neutral	0.129
RS1	O15537-1.2	S51M	Neutral	0.055
RS1	O15537-1.2	S51N	Neutral	0.004
RS1	O15537-1.2	S51P	Neutral	0.087
RS1	O15537-1.2	S51Q	Neutral	0.061
RS1	O15537-1.2	S51R	Neutral	0.131
RS1	O15537-1.2	S51T	Neutral	0.006
RS1	O15537-1.2	S51V	Neutral	0.223
RS1	O15537-1.2	S51W	Neutral	0.369
RS1	O15537-1.2	S51Y	Neutral	0.451
RS1	O15537-1.2	A52C	Neutral	0.0
RS1	O15537-1.2	A52D	Neutral	0.001
RS1	O15537-1.2	A52E	Neutral	0.0
RS1	O15537-1.2	A52F	Neutral	0.0
RS1	O15537-1.2	A52G	Neutral	0.0
RS1	O15537-1.2	A52H	Neutral	0.004
RS1	O15537-1.2	A52I	Neutral	0.0
RS1	O15537-1.2	A52K	Neutral	0.0
RS1	O15537-1.2	A52L	Neutral	0.0
RS1	O15537-1.2	A52M	Neutral	0.0
RS1	O15537-1.2	A52N	Neutral	0.001
RS1	O15537-1.2	A52P	Neutral	0.0
RS1	O15537-1.2	A52Q	Neutral	0.0
RS1	O15537-1.2	A52R	Neutral	0.0
RS1	O15537-1.2	A52S	Neutral	0.0
RS1	O15537-1.2	A52T	Neutral	0.0
RS1	O15537-1.2	A52V	Neutral	0.0
RS1	O15537-1.2	A52W	Neutral	0.002
RS1	O15537-1.2	A52Y	Neutral	0.002
RS1	O15537-1.2	G53A	Neutral	0.0
RS1	O15537-1.2	G53C	Neutral	0.003
RS1	O15537-1.2	G53D	Neutral	0.0
RS1	O15537-1.2	G53E	Neutral	0.001
RS1	O15537-1.2	G53F	Neutral	0.001
RS1	O15537-1.2	G53H	Neutral	0.004
RS1	O15537-1.2	G53I	Neutral	0.007
RS1	O15537-1.2	G53K	Neutral	0.001
RS1	O15537-1.2	G53L	Neutral	0.009
RS1	O15537-1.2	G53M	Neutral	0.004
RS1	O15537-1.2	G53N	Neutral	0.0
RS1	O15537-1.2	G53P	Neutral	0.001
RS1	O15537-1.2	G53Q	Neutral	0.004
RS1	O15537-1.2	G53R	Neutral	0.001
RS1	O15537-1.2	G53S	Neutral	0.0
RS1	O15537-1.2	G53T	Neutral	0.002
RS1	O15537-1.2	G53V	Neutral	0.003
RS1	O15537-1.2	G53W	Neutral	0.0
RS1	O15537-1.2	G53Y	Neutral	0.008
RS1	O15537-1.2	A54C	Neutral	0.0
RS1	O15537-1.2	A54D	Neutral	0.001
RS1	O15537-1.2	A54E	Neutral	0.0
RS1	O15537-1.2	A54F	Neutral	0.001
RS1	O15537-1.2	A54G	Neutral	0.0
RS1	O15537-1.2	A54H	Neutral	0.01
RS1	O15537-1.2	A54I	Neutral	0.0
RS1	O15537-1.2	A54K	Neutral	0.0
RS1	O15537-1.2	A54L	Neutral	0.0
RS1	O15537-1.2	A54M	Neutral	0.0
RS1	O15537-1.2	A54N	Neutral	0.002
RS1	O15537-1.2	A54P	Neutral	0.001
RS1	O15537-1.2	A54Q	Neutral	0.001
RS1	O15537-1.2	A54R	Neutral	0.0
RS1	O15537-1.2	A54S	Neutral	0.0
RS1	O15537-1.2	A54T	Neutral	0.0
RS1	O15537-1.2	A54V	Neutral	0.0
RS1	O15537-1.2	A54W	Neutral	0.004
RS1	O15537-1.2	A54Y	Neutral	0.006
RS1	O15537-1.2	T55A	Neutral	0.0
RS1	O15537-1.2	T55C	Neutral	0.0
RS1	O15537-1.2	T55D	Neutral	0.0
RS1	O15537-1.2	T55E	Neutral	0.0
RS1	O15537-1.2	T55F	Neutral	0.0
RS1	O15537-1.2	T55G	Neutral	0.0
RS1	O15537-1.2	T55H	Neutral	0.0
RS1	O15537-1.2	T55I	Neutral	0.0
RS1	O15537-1.2	T55K	Neutral	0.0
RS1	O15537-1.2	T55L	Neutral	0.0
RS1	O15537-1.2	T55M	Neutral	0.0
RS1	O15537-1.2	T55N	Neutral	0.0
RS1	O15537-1.2	T55P	Neutral	0.0
RS1	O15537-1.2	T55Q	Neutral	0.0
RS1	O15537-1.2	T55R	Neutral	0.0
RS1	O15537-1.2	T55S	Neutral	0.0
RS1	O15537-1.2	T55V	Neutral	0.0
RS1	O15537-1.2	T55W	Neutral	0.0
RS1	O15537-1.2	T55Y	Neutral	0.0
RS1	O15537-1.2	S56A	Neutral	0.0
RS1	O15537-1.2	S56C	Neutral	0.0
RS1	O15537-1.2	S56D	Neutral	0.0
RS1	O15537-1.2	S56E	Neutral	0.0
RS1	O15537-1.2	S56F	Neutral	0.001
RS1	O15537-1.2	S56G	Neutral	0.001
RS1	O15537-1.2	S56H	Neutral	0.004
RS1	O15537-1.2	S56I	Neutral	0.001
RS1	O15537-1.2	S56K	Neutral	0.0
RS1	O15537-1.2	S56L	Neutral	0.001
RS1	O15537-1.2	S56M	Neutral	0.0
RS1	O15537-1.2	S56N	Neutral	0.0
RS1	O15537-1.2	S56P	Neutral	0.001
RS1	O15537-1.2	S56Q	Neutral	0.001
RS1	O15537-1.2	S56R	Neutral	0.001
RS1	O15537-1.2	S56T	Neutral	0.0
RS1	O15537-1.2	S56V	Neutral	0.002
RS1	O15537-1.2	S56W	Neutral	0.005
RS1	O15537-1.2	S56Y	Neutral	0.007
RS1	O15537-1.2	L57A	Neutral	0.327
RS1	O15537-1.2	L57C	Pathogenic	0.578
RS1	O15537-1.2	L57D	Pathogenic	0.915
RS1	O15537-1.2	L57E	Pathogenic	0.623
RS1	O15537-1.2	L57F	Neutral	0.329
RS1	O15537-1.2	L57G	Pathogenic	0.989
RS1	O15537-1.2	L57H	Pathogenic	0.867
RS1	O15537-1.2	L57I	Neutral	0.01
RS1	O15537-1.2	L57K	Neutral	0.108
RS1	O15537-1.2	L57M	Neutral	0.005
RS1	O15537-1.2	L57N	Pathogenic	0.684
RS1	O15537-1.2	L57P	Pathogenic	0.969
RS1	O15537-1.2	L57Q	Neutral	0.351
RS1	O15537-1.2	L57R	Neutral	0.125
RS1	O15537-1.2	L57S	Pathogenic	0.591
RS1	O15537-1.2	L57T	Neutral	0.228
RS1	O15537-1.2	L57V	Neutral	0.038
RS1	O15537-1.2	L57W	Pathogenic	0.926
RS1	O15537-1.2	L57Y	Neutral	0.488
RS1	O15537-1.2	D58A	Neutral	0.014
RS1	O15537-1.2	D58C	Neutral	0.018
RS1	O15537-1.2	D58E	Neutral	0.0
RS1	O15537-1.2	D58F	Neutral	0.007
RS1	O15537-1.2	D58G	Neutral	0.005
RS1	O15537-1.2	D58H	Neutral	0.003
RS1	O15537-1.2	D58I	Neutral	0.005
RS1	O15537-1.2	D58K	Neutral	0.016
RS1	O15537-1.2	D58L	Neutral	0.041
RS1	O15537-1.2	D58M	Neutral	0.017
RS1	O15537-1.2	D58N	Neutral	0.0
RS1	O15537-1.2	D58P	Neutral	0.001
RS1	O15537-1.2	D58Q	Neutral	0.001
RS1	O15537-1.2	D58R	Neutral	0.109
RS1	O15537-1.2	D58S	Neutral	0.001
RS1	O15537-1.2	D58T	Neutral	0.002
RS1	O15537-1.2	D58V	Neutral	0.013
RS1	O15537-1.2	D58W	Neutral	0.026
RS1	O15537-1.2	D58Y	Neutral	0.036
RS1	O15537-1.2	C59A	Pathogenic	1.0
RS1	O15537-1.2	C59D	Pathogenic	1.0
RS1	O15537-1.2	C59E	Pathogenic	1.0
RS1	O15537-1.2	C59F	Pathogenic	1.0
RS1	O15537-1.2	C59G	Pathogenic	1.0
RS1	O15537-1.2	C59H	Pathogenic	1.0
RS1	O15537-1.2	C59I	Pathogenic	1.0
RS1	O15537-1.2	C59K	Pathogenic	1.0
RS1	O15537-1.2	C59L	Pathogenic	1.0
RS1	O15537-1.2	C59M	Pathogenic	1.0
RS1	O15537-1.2	C59N	Pathogenic	1.0
RS1	O15537-1.2	C59P	Pathogenic	1.0
RS1	O15537-1.2	C59Q	Pathogenic	1.0
RS1	O15537-1.2	C59R	Pathogenic	1.0
RS1	O15537-1.2	C59S	Pathogenic	1.0
RS1	O15537-1.2	C59T	Pathogenic	1.0
RS1	O15537-1.2	C59V	Pathogenic	1.0
RS1	O15537-1.2	C59W	Pathogenic	1.0
RS1	O15537-1.2	C59Y	Pathogenic	1.0
RS1	O15537-1.2	I60A	Neutral	0.211
RS1	O15537-1.2	I60C	Neutral	0.429
RS1	O15537-1.2	I60D	Neutral	0.479
RS1	O15537-1.2	I60E	Neutral	0.475
RS1	O15537-1.2	I60F	Neutral	0.275
RS1	O15537-1.2	I60G	Pathogenic	0.981
RS1	O15537-1.2	I60H	Pathogenic	0.782
RS1	O15537-1.2	I60K	Neutral	0.299
RS1	O15537-1.2	I60L	Neutral	0.007
RS1	O15537-1.2	I60M	Neutral	0.016
RS1	O15537-1.2	I60N	Pathogenic	0.542
RS1	O15537-1.2	I60P	Pathogenic	0.946
RS1	O15537-1.2	I60Q	Pathogenic	0.656
RS1	O15537-1.2	I60R	Neutral	0.335
RS1	O15537-1.2	I60S	Neutral	0.443
RS1	O15537-1.2	I60T	Neutral	0.14
RS1	O15537-1.2	I60V	Neutral	0.001
RS1	O15537-1.2	I60W	Pathogenic	0.985
RS1	O15537-1.2	I60Y	Neutral	0.344
RS1	O15537-1.2	P61A	Pathogenic	0.998
RS1	O15537-1.2	P61C	Pathogenic	1.0
RS1	O15537-1.2	P61D	Pathogenic	0.978
RS1	O15537-1.2	P61E	Pathogenic	0.987
RS1	O15537-1.2	P61F	Pathogenic	1.0
RS1	O15537-1.2	P61G	Pathogenic	1.0
RS1	O15537-1.2	P61H	Pathogenic	1.0
RS1	O15537-1.2	P61I	Pathogenic	1.0
RS1	O15537-1.2	P61K	Pathogenic	0.983
RS1	O15537-1.2	P61L	Pathogenic	1.0
RS1	O15537-1.2	P61M	Pathogenic	1.0
RS1	O15537-1.2	P61N	Pathogenic	0.998
RS1	O15537-1.2	P61Q	Pathogenic	0.995
RS1	O15537-1.2	P61R	Pathogenic	0.998
RS1	O15537-1.2	P61S	Pathogenic	0.996
RS1	O15537-1.2	P61T	Pathogenic	0.997
RS1	O15537-1.2	P61V	Pathogenic	1.0
RS1	O15537-1.2	P61W	Pathogenic	1.0
RS1	O15537-1.2	P61Y	Pathogenic	1.0
RS1	O15537-1.2	E62A	Pathogenic	0.994
RS1	O15537-1.2	E62C	Pathogenic	1.0
RS1	O15537-1.2	E62D	Pathogenic	0.7
RS1	O15537-1.2	E62F	Pathogenic	0.997
RS1	O15537-1.2	E62G	Pathogenic	1.0
RS1	O15537-1.2	E62H	Pathogenic	0.96
RS1	O15537-1.2	E62I	Pathogenic	0.996
RS1	O15537-1.2	E62K	Pathogenic	0.916
RS1	O15537-1.2	E62L	Pathogenic	0.997
RS1	O15537-1.2	E62M	Pathogenic	0.992
RS1	O15537-1.2	E62N	Pathogenic	0.991
RS1	O15537-1.2	E62P	Pathogenic	0.983
RS1	O15537-1.2	E62Q	Pathogenic	0.521
RS1	O15537-1.2	E62R	Pathogenic	0.988
RS1	O15537-1.2	E62S	Pathogenic	0.98
RS1	O15537-1.2	E62T	Pathogenic	0.993
RS1	O15537-1.2	E62V	Pathogenic	0.991
RS1	O15537-1.2	E62W	Pathogenic	0.995
RS1	O15537-1.2	E62Y	Pathogenic	0.996
RS1	O15537-1.2	C63A	Pathogenic	1.0
RS1	O15537-1.2	C63D	Pathogenic	1.0
RS1	O15537-1.2	C63E	Pathogenic	1.0
RS1	O15537-1.2	C63F	Pathogenic	1.0
RS1	O15537-1.2	C63G	Pathogenic	1.0
RS1	O15537-1.2	C63H	Pathogenic	1.0
RS1	O15537-1.2	C63I	Pathogenic	1.0
RS1	O15537-1.2	C63K	Pathogenic	1.0
RS1	O15537-1.2	C63L	Pathogenic	1.0
RS1	O15537-1.2	C63M	Pathogenic	1.0
RS1	O15537-1.2	C63N	Pathogenic	1.0
RS1	O15537-1.2	C63P	Pathogenic	1.0
RS1	O15537-1.2	C63Q	Pathogenic	1.0
RS1	O15537-1.2	C63R	Pathogenic	1.0
RS1	O15537-1.2	C63S	Pathogenic	1.0
RS1	O15537-1.2	C63T	Pathogenic	1.0
RS1	O15537-1.2	C63V	Pathogenic	1.0
RS1	O15537-1.2	C63W	Pathogenic	1.0
RS1	O15537-1.2	C63Y	Pathogenic	1.0
RS1	O15537-1.2	P64A	Pathogenic	0.998
RS1	O15537-1.2	P64C	Pathogenic	1.0
RS1	O15537-1.2	P64D	Pathogenic	0.982
RS1	O15537-1.2	P64E	Pathogenic	0.989
RS1	O15537-1.2	P64F	Pathogenic	1.0
RS1	O15537-1.2	P64G	Pathogenic	1.0
RS1	O15537-1.2	P64H	Pathogenic	1.0
RS1	O15537-1.2	P64I	Pathogenic	1.0
RS1	O15537-1.2	P64K	Pathogenic	0.986
RS1	O15537-1.2	P64L	Pathogenic	1.0
RS1	O15537-1.2	P64M	Pathogenic	1.0
RS1	O15537-1.2	P64N	Pathogenic	0.998
RS1	O15537-1.2	P64Q	Pathogenic	0.996
RS1	O15537-1.2	P64R	Pathogenic	0.998
RS1	O15537-1.2	P64S	Pathogenic	0.997
RS1	O15537-1.2	P64T	Pathogenic	0.998
RS1	O15537-1.2	P64V	Pathogenic	1.0
RS1	O15537-1.2	P64W	Pathogenic	1.0
RS1	O15537-1.2	P64Y	Pathogenic	1.0
RS1	O15537-1.2	Y65A	Pathogenic	1.0
RS1	O15537-1.2	Y65C	Pathogenic	1.0
RS1	O15537-1.2	Y65D	Pathogenic	1.0
RS1	O15537-1.2	Y65E	Pathogenic	0.997
RS1	O15537-1.2	Y65F	Neutral	0.084
RS1	O15537-1.2	Y65G	Pathogenic	1.0
RS1	O15537-1.2	Y65H	Neutral	0.434
RS1	O15537-1.2	Y65I	Pathogenic	0.995
RS1	O15537-1.2	Y65K	Pathogenic	0.991
RS1	O15537-1.2	Y65L	Pathogenic	0.996
RS1	O15537-1.2	Y65M	Pathogenic	0.998
RS1	O15537-1.2	Y65N	Pathogenic	0.998
RS1	O15537-1.2	Y65P	Pathogenic	1.0
RS1	O15537-1.2	Y65Q	Pathogenic	0.991
RS1	O15537-1.2	Y65R	Pathogenic	0.991
RS1	O15537-1.2	Y65S	Pathogenic	0.999
RS1	O15537-1.2	Y65T	Pathogenic	1.0
RS1	O15537-1.2	Y65V	Pathogenic	0.999
RS1	O15537-1.2	Y65W	Neutral	0.233
RS1	O15537-1.2	H66A	Pathogenic	1.0
RS1	O15537-1.2	H66C	Pathogenic	1.0
RS1	O15537-1.2	H66D	Pathogenic	0.988
RS1	O15537-1.2	H66E	Pathogenic	0.927
RS1	O15537-1.2	H66F	Pathogenic	0.941
RS1	O15537-1.2	H66G	Pathogenic	1.0
RS1	O15537-1.2	H66I	Pathogenic	0.998
RS1	O15537-1.2	H66K	Pathogenic	0.979
RS1	O15537-1.2	H66L	Pathogenic	0.999
RS1	O15537-1.2	H66M	Pathogenic	0.996
RS1	O15537-1.2	H66N	Pathogenic	0.72
RS1	O15537-1.2	H66P	Pathogenic	0.999
RS1	O15537-1.2	H66Q	Pathogenic	0.964
RS1	O15537-1.2	H66R	Pathogenic	0.894
RS1	O15537-1.2	H66S	Pathogenic	0.998
RS1	O15537-1.2	H66T	Pathogenic	1.0
RS1	O15537-1.2	H66V	Pathogenic	0.999
RS1	O15537-1.2	H66W	Pathogenic	0.985
RS1	O15537-1.2	H66Y	Neutral	0.251
RS1	O15537-1.2	K67A	Neutral	0.105
RS1	O15537-1.2	K67C	Neutral	0.49
RS1	O15537-1.2	K67D	Neutral	0.403
RS1	O15537-1.2	K67E	Neutral	0.009
RS1	O15537-1.2	K67F	Neutral	0.085
RS1	O15537-1.2	K67G	Pathogenic	0.648
RS1	O15537-1.2	K67H	Neutral	0.071
RS1	O15537-1.2	K67I	Neutral	0.097
RS1	O15537-1.2	K67L	Neutral	0.02
RS1	O15537-1.2	K67M	Neutral	0.008
RS1	O15537-1.2	K67N	Neutral	0.065
RS1	O15537-1.2	K67P	Neutral	0.035
RS1	O15537-1.2	K67Q	Neutral	0.004
RS1	O15537-1.2	K67R	Neutral	0.002
RS1	O15537-1.2	K67S	Neutral	0.032
RS1	O15537-1.2	K67T	Neutral	0.08
RS1	O15537-1.2	K67V	Neutral	0.066
RS1	O15537-1.2	K67W	Neutral	0.054
RS1	O15537-1.2	K67Y	Neutral	0.075
RS1	O15537-1.2	P68A	Pathogenic	0.941
RS1	O15537-1.2	P68C	Pathogenic	0.998
RS1	O15537-1.2	P68D	Pathogenic	0.577
RS1	O15537-1.2	P68E	Pathogenic	0.699
RS1	O15537-1.2	P68F	Pathogenic	0.999
RS1	O15537-1.2	P68G	Pathogenic	0.987
RS1	O15537-1.2	P68H	Pathogenic	0.987
RS1	O15537-1.2	P68I	Pathogenic	0.995
RS1	O15537-1.2	P68K	Pathogenic	0.633
RS1	O15537-1.2	P68L	Pathogenic	0.996
RS1	O15537-1.2	P68M	Pathogenic	0.99
RS1	O15537-1.2	P68N	Pathogenic	0.93
RS1	O15537-1.2	P68Q	Pathogenic	0.851
RS1	O15537-1.2	P68R	Pathogenic	0.929
RS1	O15537-1.2	P68S	Pathogenic	0.88
RS1	O15537-1.2	P68T	Pathogenic	0.914
RS1	O15537-1.2	P68V	Pathogenic	0.987
RS1	O15537-1.2	P68W	Pathogenic	0.999
RS1	O15537-1.2	P68Y	Pathogenic	0.999
RS1	O15537-1.2	L69A	Pathogenic	0.987
RS1	O15537-1.2	L69C	Pathogenic	0.996
RS1	O15537-1.2	L69D	Pathogenic	0.999
RS1	O15537-1.2	L69E	Pathogenic	0.996
RS1	O15537-1.2	L69F	Pathogenic	0.988
RS1	O15537-1.2	L69G	Pathogenic	1.0
RS1	O15537-1.2	L69H	Pathogenic	0.999
RS1	O15537-1.2	L69I	Pathogenic	0.612
RS1	O15537-1.2	L69K	Pathogenic	0.951
RS1	O15537-1.2	L69M	Neutral	0.434
RS1	O15537-1.2	L69N	Pathogenic	0.997
RS1	O15537-1.2	L69P	Pathogenic	1.0
RS1	O15537-1.2	L69Q	Pathogenic	0.989
RS1	O15537-1.2	L69R	Pathogenic	0.959
RS1	O15537-1.2	L69S	Pathogenic	0.996
RS1	O15537-1.2	L69T	Pathogenic	0.98
RS1	O15537-1.2	L69V	Pathogenic	0.864
RS1	O15537-1.2	L69W	Pathogenic	1.0
RS1	O15537-1.2	L69Y	Pathogenic	0.994
RS1	O15537-1.2	G70A	Pathogenic	0.992
RS1	O15537-1.2	G70C	Pathogenic	1.0
RS1	O15537-1.2	G70D	Pathogenic	0.998
RS1	O15537-1.2	G70E	Pathogenic	1.0
RS1	O15537-1.2	G70F	Pathogenic	1.0
RS1	O15537-1.2	G70H	Pathogenic	1.0
RS1	O15537-1.2	G70I	Pathogenic	1.0
RS1	O15537-1.2	G70K	Pathogenic	1.0
RS1	O15537-1.2	G70L	Pathogenic	1.0
RS1	O15537-1.2	G70M	Pathogenic	1.0
RS1	O15537-1.2	G70N	Pathogenic	0.991
RS1	O15537-1.2	G70P	Pathogenic	1.0
RS1	O15537-1.2	G70Q	Pathogenic	1.0
RS1	O15537-1.2	G70R	Pathogenic	1.0
RS1	O15537-1.2	G70S	Pathogenic	0.996
RS1	O15537-1.2	G70T	Pathogenic	1.0
RS1	O15537-1.2	G70V	Pathogenic	1.0
RS1	O15537-1.2	G70W	Pathogenic	0.998
RS1	O15537-1.2	G70Y	Pathogenic	1.0
RS1	O15537-1.2	F71A	Pathogenic	0.998
RS1	O15537-1.2	F71C	Pathogenic	0.999
RS1	O15537-1.2	F71D	Pathogenic	0.996
RS1	O15537-1.2	F71E	Pathogenic	0.996
RS1	O15537-1.2	F71G	Pathogenic	1.0
RS1	O15537-1.2	F71H	Pathogenic	0.962
RS1	O15537-1.2	F71I	Pathogenic	0.989
RS1	O15537-1.2	F71K	Pathogenic	0.989
RS1	O15537-1.2	F71L	Pathogenic	0.988
RS1	O15537-1.2	F71M	Pathogenic	0.969
RS1	O15537-1.2	F71N	Pathogenic	0.997
RS1	O15537-1.2	F71P	Pathogenic	1.0
RS1	O15537-1.2	F71Q	Pathogenic	0.998
RS1	O15537-1.2	F71R	Pathogenic	0.991
RS1	O15537-1.2	F71S	Pathogenic	0.996
RS1	O15537-1.2	F71T	Pathogenic	0.997
RS1	O15537-1.2	F71V	Pathogenic	0.996
RS1	O15537-1.2	F71W	Pathogenic	0.884
RS1	O15537-1.2	F71Y	Neutral	0.06
RS1	O15537-1.2	E72A	Pathogenic	0.996
RS1	O15537-1.2	E72C	Pathogenic	1.0
RS1	O15537-1.2	E72D	Pathogenic	0.774
RS1	O15537-1.2	E72F	Pathogenic	0.998
RS1	O15537-1.2	E72G	Pathogenic	1.0
RS1	O15537-1.2	E72H	Pathogenic	0.972
RS1	O15537-1.2	E72I	Pathogenic	0.997
RS1	O15537-1.2	E72K	Pathogenic	0.942
RS1	O15537-1.2	E72L	Pathogenic	0.998
RS1	O15537-1.2	E72M	Pathogenic	0.995
RS1	O15537-1.2	E72N	Pathogenic	0.994
RS1	O15537-1.2	E72P	Pathogenic	0.988
RS1	O15537-1.2	E72Q	Pathogenic	0.615
RS1	O15537-1.2	E72R	Pathogenic	0.992
RS1	O15537-1.2	E72S	Pathogenic	0.987
RS1	O15537-1.2	E72T	Pathogenic	0.995
RS1	O15537-1.2	E72V	Pathogenic	0.994
RS1	O15537-1.2	E72W	Pathogenic	0.997
RS1	O15537-1.2	E72Y	Pathogenic	0.998
RS1	O15537-1.2	S73A	Neutral	0.14
RS1	O15537-1.2	S73C	Pathogenic	0.664
RS1	O15537-1.2	S73D	Neutral	0.368
RS1	O15537-1.2	S73E	Neutral	0.498
RS1	O15537-1.2	S73F	Pathogenic	0.846
RS1	O15537-1.2	S73G	Pathogenic	0.718
RS1	O15537-1.2	S73H	Pathogenic	0.945
RS1	O15537-1.2	S73I	Pathogenic	0.818
RS1	O15537-1.2	S73K	Neutral	0.425
RS1	O15537-1.2	S73L	Pathogenic	0.846
RS1	O15537-1.2	S73M	Pathogenic	0.683
RS1	O15537-1.2	S73N	Neutral	0.12
RS1	O15537-1.2	S73P	Pathogenic	0.779
RS1	O15537-1.2	S73Q	Pathogenic	0.709
RS1	O15537-1.2	S73R	Pathogenic	0.849
RS1	O15537-1.2	S73T	Neutral	0.182
RS1	O15537-1.2	S73V	Pathogenic	0.915
RS1	O15537-1.2	S73W	Pathogenic	0.956
RS1	O15537-1.2	S73Y	Pathogenic	0.968
RS1	O15537-1.2	G74A	Pathogenic	0.901
RS1	O15537-1.2	G74C	Pathogenic	0.999
RS1	O15537-1.2	G74D	Pathogenic	0.971
RS1	O15537-1.2	G74E	Pathogenic	0.997
RS1	O15537-1.2	G74F	Pathogenic	0.997
RS1	O15537-1.2	G74H	Pathogenic	0.999
RS1	O15537-1.2	G74I	Pathogenic	0.999
RS1	O15537-1.2	G74K	Pathogenic	0.996
RS1	O15537-1.2	G74L	Pathogenic	1.0
RS1	O15537-1.2	G74M	Pathogenic	0.999
RS1	O15537-1.2	G74N	Pathogenic	0.888
RS1	O15537-1.2	G74P	Pathogenic	0.996
RS1	O15537-1.2	G74Q	Pathogenic	0.999
RS1	O15537-1.2	G74R	Pathogenic	0.997
RS1	O15537-1.2	G74S	Pathogenic	0.944
RS1	O15537-1.2	G74T	Pathogenic	0.998
RS1	O15537-1.2	G74V	Pathogenic	0.999
RS1	O15537-1.2	G74W	Pathogenic	0.972
RS1	O15537-1.2	G74Y	Pathogenic	1.0
RS1	O15537-1.2	E75A	Neutral	0.011
RS1	O15537-1.2	E75C	Neutral	0.379
RS1	O15537-1.2	E75D	Neutral	0.0
RS1	O15537-1.2	E75F	Neutral	0.02
RS1	O15537-1.2	E75G	Neutral	0.154
RS1	O15537-1.2	E75H	Neutral	0.002
RS1	O15537-1.2	E75I	Neutral	0.016
RS1	O15537-1.2	E75K	Neutral	0.001
RS1	O15537-1.2	E75L	Neutral	0.02
RS1	O15537-1.2	E75M	Neutral	0.008
RS1	O15537-1.2	E75N	Neutral	0.007
RS1	O15537-1.2	E75P	Neutral	0.004
RS1	O15537-1.2	E75Q	Neutral	0.0
RS1	O15537-1.2	E75R	Neutral	0.005
RS1	O15537-1.2	E75S	Neutral	0.003
RS1	O15537-1.2	E75T	Neutral	0.009
RS1	O15537-1.2	E75V	Neutral	0.007
RS1	O15537-1.2	E75W	Neutral	0.012
RS1	O15537-1.2	E75Y	Neutral	0.017
RS1	O15537-1.2	V76A	Pathogenic	0.669
RS1	O15537-1.2	V76C	Pathogenic	0.973
RS1	O15537-1.2	V76D	Pathogenic	0.978
RS1	O15537-1.2	V76E	Pathogenic	0.886
RS1	O15537-1.2	V76F	Pathogenic	0.957
RS1	O15537-1.2	V76G	Pathogenic	0.997
RS1	O15537-1.2	V76H	Pathogenic	0.996
RS1	O15537-1.2	V76I	Neutral	0.011
RS1	O15537-1.2	V76K	Pathogenic	0.852
RS1	O15537-1.2	V76L	Neutral	0.352
RS1	O15537-1.2	V76M	Pathogenic	0.578
RS1	O15537-1.2	V76N	Pathogenic	0.983
RS1	O15537-1.2	V76P	Pathogenic	0.992
RS1	O15537-1.2	V76Q	Pathogenic	0.95
RS1	O15537-1.2	V76R	Pathogenic	0.978
RS1	O15537-1.2	V76S	Pathogenic	0.975
RS1	O15537-1.2	V76T	Pathogenic	0.552
RS1	O15537-1.2	V76W	Pathogenic	0.998
RS1	O15537-1.2	V76Y	Pathogenic	0.979
RS1	O15537-1.2	T77A	Neutral	0.068
RS1	O15537-1.2	T77C	Neutral	0.085
RS1	O15537-1.2	T77D	Neutral	0.046
RS1	O15537-1.2	T77E	Neutral	0.071
RS1	O15537-1.2	T77F	Neutral	0.173
RS1	O15537-1.2	T77G	Pathogenic	0.729
RS1	O15537-1.2	T77H	Pathogenic	0.72
RS1	O15537-1.2	T77I	Neutral	0.026
RS1	O15537-1.2	T77K	Neutral	0.054
RS1	O15537-1.2	T77L	Neutral	0.032
RS1	O15537-1.2	T77M	Neutral	0.076
RS1	O15537-1.2	T77N	Neutral	0.01
RS1	O15537-1.2	T77P	Neutral	0.128
RS1	O15537-1.2	T77Q	Neutral	0.158
RS1	O15537-1.2	T77R	Neutral	0.063
RS1	O15537-1.2	T77S	Neutral	0.006
RS1	O15537-1.2	T77V	Neutral	0.01
RS1	O15537-1.2	T77W	Neutral	0.114
RS1	O15537-1.2	T77Y	Pathogenic	0.538
RS1	O15537-1.2	P78A	Neutral	0.088
RS1	O15537-1.2	P78C	Pathogenic	0.8
RS1	O15537-1.2	P78D	Neutral	0.008
RS1	O15537-1.2	P78E	Neutral	0.014
RS1	O15537-1.2	P78F	Pathogenic	0.908
RS1	O15537-1.2	P78G	Neutral	0.312
RS1	O15537-1.2	P78H	Neutral	0.322
RS1	O15537-1.2	P78I	Pathogenic	0.557
RS1	O15537-1.2	P78K	Neutral	0.01
RS1	O15537-1.2	P78L	Pathogenic	0.606
RS1	O15537-1.2	P78M	Neutral	0.376
RS1	O15537-1.2	P78N	Neutral	0.074
RS1	O15537-1.2	P78Q	Neutral	0.034
RS1	O15537-1.2	P78R	Neutral	0.074
RS1	O15537-1.2	P78S	Neutral	0.043
RS1	O15537-1.2	P78T	Neutral	0.061
RS1	O15537-1.2	P78V	Neutral	0.317
RS1	O15537-1.2	P78W	Pathogenic	0.858
RS1	O15537-1.2	P78Y	Pathogenic	0.895
RS1	O15537-1.2	D79A	Pathogenic	0.991
RS1	O15537-1.2	D79C	Pathogenic	0.993
RS1	O15537-1.2	D79E	Neutral	0.282
RS1	O15537-1.2	D79F	Pathogenic	0.982
RS1	O15537-1.2	D79G	Pathogenic	0.978
RS1	O15537-1.2	D79H	Pathogenic	0.963
RS1	O15537-1.2	D79I	Pathogenic	0.978
RS1	O15537-1.2	D79K	Pathogenic	0.992
RS1	O15537-1.2	D79L	Pathogenic	0.997
RS1	O15537-1.2	D79M	Pathogenic	0.993
RS1	O15537-1.2	D79N	Pathogenic	0.658
RS1	O15537-1.2	D79P	Pathogenic	0.848
RS1	O15537-1.2	D79Q	Pathogenic	0.885
RS1	O15537-1.2	D79R	Pathogenic	0.999
RS1	O15537-1.2	D79S	Pathogenic	0.833
RS1	O15537-1.2	D79T	Pathogenic	0.934
RS1	O15537-1.2	D79V	Pathogenic	0.991
RS1	O15537-1.2	D79W	Pathogenic	0.995
RS1	O15537-1.2	D79Y	Pathogenic	0.997
RS1	O15537-1.2	Q80A	Pathogenic	0.998
RS1	O15537-1.2	Q80C	Pathogenic	1.0
RS1	O15537-1.2	Q80D	Pathogenic	0.985
RS1	O15537-1.2	Q80E	Pathogenic	0.608
RS1	O15537-1.2	Q80F	Pathogenic	0.999
RS1	O15537-1.2	Q80G	Pathogenic	1.0
RS1	O15537-1.2	Q80H	Pathogenic	0.986
RS1	O15537-1.2	Q80I	Pathogenic	0.999
RS1	O15537-1.2	Q80K	Pathogenic	0.864
RS1	O15537-1.2	Q80L	Pathogenic	0.993
RS1	O15537-1.2	Q80M	Pathogenic	0.9
RS1	O15537-1.2	Q80N	Pathogenic	0.988
RS1	O15537-1.2	Q80P	Pathogenic	0.995
RS1	O15537-1.2	Q80R	Pathogenic	0.883
RS1	O15537-1.2	Q80S	Pathogenic	0.994
RS1	O15537-1.2	Q80T	Pathogenic	0.998
RS1	O15537-1.2	Q80V	Pathogenic	0.997
RS1	O15537-1.2	Q80W	Pathogenic	0.989
RS1	O15537-1.2	Q80Y	Pathogenic	0.992
RS1	O15537-1.2	I81A	Pathogenic	0.927
RS1	O15537-1.2	I81C	Pathogenic	0.973
RS1	O15537-1.2	I81D	Pathogenic	0.978
RS1	O15537-1.2	I81E	Pathogenic	0.977
RS1	O15537-1.2	I81F	Pathogenic	0.948
RS1	O15537-1.2	I81G	Pathogenic	1.0
RS1	O15537-1.2	I81H	Pathogenic	0.994
RS1	O15537-1.2	I81K	Pathogenic	0.953
RS1	O15537-1.2	I81L	Neutral	0.237
RS1	O15537-1.2	I81M	Neutral	0.443
RS1	O15537-1.2	I81N	Pathogenic	0.983
RS1	O15537-1.2	I81P	Pathogenic	0.999
RS1	O15537-1.2	I81Q	Pathogenic	0.989
RS1	O15537-1.2	I81R	Pathogenic	0.96
RS1	O15537-1.2	I81S	Pathogenic	0.974
RS1	O15537-1.2	I81T	Pathogenic	0.885
RS1	O15537-1.2	I81V	Neutral	0.024
RS1	O15537-1.2	I81W	Pathogenic	1.0
RS1	O15537-1.2	I81Y	Pathogenic	0.961
RS1	O15537-1.2	T82A	Neutral	0.114
RS1	O15537-1.2	T82C	Neutral	0.142
RS1	O15537-1.2	T82D	Neutral	0.078
RS1	O15537-1.2	T82E	Neutral	0.12
RS1	O15537-1.2	T82F	Neutral	0.27
RS1	O15537-1.2	T82G	Pathogenic	0.826
RS1	O15537-1.2	T82H	Pathogenic	0.82
RS1	O15537-1.2	T82I	Neutral	0.045
RS1	O15537-1.2	T82K	Neutral	0.092
RS1	O15537-1.2	T82L	Neutral	0.055
RS1	O15537-1.2	T82M	Neutral	0.127
RS1	O15537-1.2	T82N	Neutral	0.018
RS1	O15537-1.2	T82P	Neutral	0.207
RS1	O15537-1.2	T82Q	Neutral	0.25
RS1	O15537-1.2	T82R	Neutral	0.107
RS1	O15537-1.2	T82S	Neutral	0.011
RS1	O15537-1.2	T82V	Neutral	0.017
RS1	O15537-1.2	T82W	Neutral	0.186
RS1	O15537-1.2	T82Y	Pathogenic	0.674
RS1	O15537-1.2	C83A	Pathogenic	0.977
RS1	O15537-1.2	C83D	Pathogenic	0.999
RS1	O15537-1.2	C83E	Pathogenic	1.0
RS1	O15537-1.2	C83F	Pathogenic	1.0
RS1	O15537-1.2	C83G	Pathogenic	1.0
RS1	O15537-1.2	C83H	Pathogenic	1.0
RS1	O15537-1.2	C83I	Pathogenic	0.996
RS1	O15537-1.2	C83K	Pathogenic	0.999
RS1	O15537-1.2	C83L	Pathogenic	0.997
RS1	O15537-1.2	C83M	Pathogenic	0.999
RS1	O15537-1.2	C83N	Pathogenic	0.999
RS1	O15537-1.2	C83P	Pathogenic	1.0
RS1	O15537-1.2	C83Q	Pathogenic	1.0
RS1	O15537-1.2	C83R	Pathogenic	0.999
RS1	O15537-1.2	C83S	Pathogenic	0.992
RS1	O15537-1.2	C83T	Pathogenic	0.995
RS1	O15537-1.2	C83V	Pathogenic	0.998
RS1	O15537-1.2	C83W	Pathogenic	0.999
RS1	O15537-1.2	C83Y	Pathogenic	1.0
RS1	O15537-1.2	S84A	Pathogenic	0.953
RS1	O15537-1.2	S84C	Pathogenic	0.996
RS1	O15537-1.2	S84D	Pathogenic	0.986
RS1	O15537-1.2	S84E	Pathogenic	0.992
RS1	O15537-1.2	S84F	Pathogenic	0.999
RS1	O15537-1.2	S84G	Pathogenic	0.997
RS1	O15537-1.2	S84H	Pathogenic	1.0
RS1	O15537-1.2	S84I	Pathogenic	0.998
RS1	O15537-1.2	S84K	Pathogenic	0.989
RS1	O15537-1.2	S84L	Pathogenic	0.999
RS1	O15537-1.2	S84M	Pathogenic	0.996
RS1	O15537-1.2	S84N	Pathogenic	0.944
RS1	O15537-1.2	S84P	Pathogenic	0.998
RS1	O15537-1.2	S84Q	Pathogenic	0.997
RS1	O15537-1.2	S84R	Pathogenic	0.999
RS1	O15537-1.2	S84T	Pathogenic	0.965
RS1	O15537-1.2	S84V	Pathogenic	0.999
RS1	O15537-1.2	S84W	Pathogenic	1.0
RS1	O15537-1.2	S84Y	Pathogenic	1.0
RS1	O15537-1.2	N85A	Pathogenic	0.998
RS1	O15537-1.2	N85C	Pathogenic	0.998
RS1	O15537-1.2	N85D	Pathogenic	0.821
RS1	O15537-1.2	N85E	Pathogenic	0.977
RS1	O15537-1.2	N85F	Pathogenic	0.994
RS1	O15537-1.2	N85G	Pathogenic	0.96
RS1	O15537-1.2	N85H	Pathogenic	0.662
RS1	O15537-1.2	N85I	Pathogenic	0.993
RS1	O15537-1.2	N85K	Pathogenic	0.97
RS1	O15537-1.2	N85L	Pathogenic	0.994
RS1	O15537-1.2	N85M	Pathogenic	0.985
RS1	O15537-1.2	N85P	Pathogenic	0.992
RS1	O15537-1.2	N85Q	Pathogenic	0.96
RS1	O15537-1.2	N85R	Pathogenic	0.974
RS1	O15537-1.2	N85S	Pathogenic	0.735
RS1	O15537-1.2	N85T	Pathogenic	0.881
RS1	O15537-1.2	N85V	Pathogenic	0.997
RS1	O15537-1.2	N85W	Pathogenic	0.998
RS1	O15537-1.2	N85Y	Pathogenic	0.993
RS1	O15537-1.2	P86A	Neutral	0.011
RS1	O15537-1.2	P86C	Neutral	0.308
RS1	O15537-1.2	P86D	Neutral	0.001
RS1	O15537-1.2	P86E	Neutral	0.002
RS1	O15537-1.2	P86F	Pathogenic	0.522
RS1	O15537-1.2	P86G	Neutral	0.048
RS1	O15537-1.2	P86H	Neutral	0.05
RS1	O15537-1.2	P86I	Neutral	0.123
RS1	O15537-1.2	P86K	Neutral	0.001
RS1	O15537-1.2	P86L	Neutral	0.146
RS1	O15537-1.2	P86M	Neutral	0.063
RS1	O15537-1.2	P86N	Neutral	0.009
RS1	O15537-1.2	P86Q	Neutral	0.004
RS1	O15537-1.2	P86R	Neutral	0.009
RS1	O15537-1.2	P86S	Neutral	0.005
RS1	O15537-1.2	P86T	Neutral	0.007
RS1	O15537-1.2	P86V	Neutral	0.049
RS1	O15537-1.2	P86W	Neutral	0.403
RS1	O15537-1.2	P86Y	Neutral	0.488
RS1	O15537-1.2	E87A	Pathogenic	0.684
RS1	O15537-1.2	E87C	Pathogenic	0.991
RS1	O15537-1.2	E87D	Neutral	0.027
RS1	O15537-1.2	E87F	Pathogenic	0.792
RS1	O15537-1.2	E87G	Pathogenic	0.971
RS1	O15537-1.2	E87H	Neutral	0.224
RS1	O15537-1.2	E87I	Pathogenic	0.758
RS1	O15537-1.2	E87K	Neutral	0.117
RS1	O15537-1.2	E87L	Pathogenic	0.793
RS1	O15537-1.2	E87M	Pathogenic	0.6
RS1	O15537-1.2	E87N	Pathogenic	0.565
RS1	O15537-1.2	E87P	Neutral	0.405
RS1	O15537-1.2	E87Q	Neutral	0.013
RS1	O15537-1.2	E87R	Pathogenic	0.502
RS1	O15537-1.2	E87S	Neutral	0.377
RS1	O15537-1.2	E87T	Pathogenic	0.618
RS1	O15537-1.2	E87V	Pathogenic	0.567
RS1	O15537-1.2	E87W	Pathogenic	0.702
RS1	O15537-1.2	E87Y	Pathogenic	0.768
RS1	O15537-1.2	Q88A	Pathogenic	0.998
RS1	O15537-1.2	Q88C	Pathogenic	1.0
RS1	O15537-1.2	Q88D	Pathogenic	0.981
RS1	O15537-1.2	Q88E	Pathogenic	0.552
RS1	O15537-1.2	Q88F	Pathogenic	0.999
RS1	O15537-1.2	Q88G	Pathogenic	1.0
RS1	O15537-1.2	Q88H	Pathogenic	0.983
RS1	O15537-1.2	Q88I	Pathogenic	0.998
RS1	O15537-1.2	Q88K	Pathogenic	0.835
RS1	O15537-1.2	Q88L	Pathogenic	0.992
RS1	O15537-1.2	Q88M	Pathogenic	0.878
RS1	O15537-1.2	Q88N	Pathogenic	0.985
RS1	O15537-1.2	Q88P	Pathogenic	0.994
RS1	O15537-1.2	Q88R	Pathogenic	0.857
RS1	O15537-1.2	Q88S	Pathogenic	0.993
RS1	O15537-1.2	Q88T	Pathogenic	0.997
RS1	O15537-1.2	Q88V	Pathogenic	0.997
RS1	O15537-1.2	Q88W	Pathogenic	0.986
RS1	O15537-1.2	Q88Y	Pathogenic	0.99
RS1	O15537-1.2	Y89A	Pathogenic	1.0
RS1	O15537-1.2	Y89C	Pathogenic	1.0
RS1	O15537-1.2	Y89D	Pathogenic	1.0
RS1	O15537-1.2	Y89E	Pathogenic	0.999
RS1	O15537-1.2	Y89F	Neutral	0.239
RS1	O15537-1.2	Y89G	Pathogenic	1.0
RS1	O15537-1.2	Y89H	Pathogenic	0.723
RS1	O15537-1.2	Y89I	Pathogenic	0.998
RS1	O15537-1.2	Y89K	Pathogenic	0.997
RS1	O15537-1.2	Y89L	Pathogenic	0.999
RS1	O15537-1.2	Y89M	Pathogenic	0.999
RS1	O15537-1.2	Y89N	Pathogenic	0.999
RS1	O15537-1.2	Y89P	Pathogenic	1.0
RS1	O15537-1.2	Y89Q	Pathogenic	0.997
RS1	O15537-1.2	Y89R	Pathogenic	0.997
RS1	O15537-1.2	Y89S	Pathogenic	1.0
RS1	O15537-1.2	Y89T	Pathogenic	1.0
RS1	O15537-1.2	Y89V	Pathogenic	1.0
RS1	O15537-1.2	Y89W	Pathogenic	0.509
RS1	O15537-1.2	V90A	Neutral	0.007
RS1	O15537-1.2	V90C	Neutral	0.12
RS1	O15537-1.2	V90D	Neutral	0.143
RS1	O15537-1.2	V90E	Neutral	0.028
RS1	O15537-1.2	V90F	Neutral	0.077
RS1	O15537-1.2	V90G	Pathogenic	0.593
RS1	O15537-1.2	V90H	Neutral	0.492
RS1	O15537-1.2	V90I	Neutral	0.0
RS1	O15537-1.2	V90K	Neutral	0.021
RS1	O15537-1.2	V90L	Neutral	0.002
RS1	O15537-1.2	V90M	Neutral	0.005
RS1	O15537-1.2	V90N	Neutral	0.177
RS1	O15537-1.2	V90P	Neutral	0.33
RS1	O15537-1.2	V90Q	Neutral	0.066
RS1	O15537-1.2	V90R	Neutral	0.14
RS1	O15537-1.2	V90S	Neutral	0.126
RS1	O15537-1.2	V90T	Neutral	0.005
RS1	O15537-1.2	V90W	Pathogenic	0.68
RS1	O15537-1.2	V90Y	Neutral	0.145
RS1	O15537-1.2	G91A	Pathogenic	0.986
RS1	O15537-1.2	G91C	Pathogenic	1.0
RS1	O15537-1.2	G91D	Pathogenic	0.996
RS1	O15537-1.2	G91E	Pathogenic	1.0
RS1	O15537-1.2	G91F	Pathogenic	1.0
RS1	O15537-1.2	G91H	Pathogenic	1.0
RS1	O15537-1.2	G91I	Pathogenic	1.0
RS1	O15537-1.2	G91K	Pathogenic	1.0
RS1	O15537-1.2	G91L	Pathogenic	1.0
RS1	O15537-1.2	G91M	Pathogenic	1.0
RS1	O15537-1.2	G91N	Pathogenic	0.984
RS1	O15537-1.2	G91P	Pathogenic	0.999
RS1	O15537-1.2	G91Q	Pathogenic	1.0
RS1	O15537-1.2	G91R	Pathogenic	1.0
RS1	O15537-1.2	G91S	Pathogenic	0.992
RS1	O15537-1.2	G91T	Pathogenic	1.0
RS1	O15537-1.2	G91V	Pathogenic	1.0
RS1	O15537-1.2	G91W	Pathogenic	0.996
RS1	O15537-1.2	G91Y	Pathogenic	1.0
RS1	O15537-1.2	W92A	Pathogenic	1.0
RS1	O15537-1.2	W92C	Pathogenic	1.0
RS1	O15537-1.2	W92D	Pathogenic	1.0
RS1	O15537-1.2	W92E	Pathogenic	0.999
RS1	O15537-1.2	W92F	Pathogenic	0.978
RS1	O15537-1.2	W92G	Pathogenic	0.999
RS1	O15537-1.2	W92H	Pathogenic	0.998
RS1	O15537-1.2	W92I	Pathogenic	1.0
RS1	O15537-1.2	W92K	Pathogenic	0.997
RS1	O15537-1.2	W92L	Pathogenic	1.0
RS1	O15537-1.2	W92M	Pathogenic	0.999
RS1	O15537-1.2	W92N	Pathogenic	1.0
RS1	O15537-1.2	W92P	Pathogenic	1.0
RS1	O15537-1.2	W92Q	Pathogenic	0.997
RS1	O15537-1.2	W92R	Pathogenic	0.996
RS1	O15537-1.2	W92S	Pathogenic	1.0
RS1	O15537-1.2	W92T	Pathogenic	0.999
RS1	O15537-1.2	W92V	Pathogenic	1.0
RS1	O15537-1.2	W92Y	Pathogenic	0.554
RS1	O15537-1.2	Y93A	Pathogenic	0.997
RS1	O15537-1.2	Y93C	Pathogenic	0.999
RS1	O15537-1.2	Y93D	Pathogenic	0.994
RS1	O15537-1.2	Y93E	Pathogenic	0.959
RS1	O15537-1.2	Y93F	Neutral	0.006
RS1	O15537-1.2	Y93G	Pathogenic	0.999
RS1	O15537-1.2	Y93H	Neutral	0.052
RS1	O15537-1.2	Y93I	Pathogenic	0.928
RS1	O15537-1.2	Y93K	Pathogenic	0.888
RS1	O15537-1.2	Y93L	Pathogenic	0.94
RS1	O15537-1.2	Y93M	Pathogenic	0.975
RS1	O15537-1.2	Y93N	Pathogenic	0.968
RS1	O15537-1.2	Y93P	Pathogenic	1.0
RS1	O15537-1.2	Y93Q	Pathogenic	0.885
RS1	O15537-1.2	Y93R	Pathogenic	0.886
RS1	O15537-1.2	Y93S	Pathogenic	0.992
RS1	O15537-1.2	Y93T	Pathogenic	0.994
RS1	O15537-1.2	Y93V	Pathogenic	0.982
RS1	O15537-1.2	Y93W	Neutral	0.021
RS1	O15537-1.2	S94A	Neutral	0.457
RS1	O15537-1.2	S94C	Pathogenic	0.911
RS1	O15537-1.2	S94D	Pathogenic	0.751
RS1	O15537-1.2	S94E	Pathogenic	0.837
RS1	O15537-1.2	S94F	Pathogenic	0.966
RS1	O15537-1.2	S94G	Pathogenic	0.93
RS1	O15537-1.2	S94H	Pathogenic	0.989
RS1	O15537-1.2	S94I	Pathogenic	0.959
RS1	O15537-1.2	S94K	Pathogenic	0.793
RS1	O15537-1.2	S94L	Pathogenic	0.966
RS1	O15537-1.2	S94M	Pathogenic	0.918
RS1	O15537-1.2	S94N	Neutral	0.414
RS1	O15537-1.2	S94P	Pathogenic	0.948
RS1	O15537-1.2	S94Q	Pathogenic	0.927
RS1	O15537-1.2	S94R	Pathogenic	0.967
RS1	O15537-1.2	S94T	Pathogenic	0.535
RS1	O15537-1.2	S94V	Pathogenic	0.982
RS1	O15537-1.2	S94W	Pathogenic	0.991
RS1	O15537-1.2	S94Y	Pathogenic	0.994
RS1	O15537-1.2	S95A	Pathogenic	0.974
RS1	O15537-1.2	S95C	Pathogenic	0.998
RS1	O15537-1.2	S95D	Pathogenic	0.993
RS1	O15537-1.2	S95E	Pathogenic	0.996
RS1	O15537-1.2	S95F	Pathogenic	0.999
RS1	O15537-1.2	S95G	Pathogenic	0.998
RS1	O15537-1.2	S95H	Pathogenic	1.0
RS1	O15537-1.2	S95I	Pathogenic	0.999
RS1	O15537-1.2	S95K	Pathogenic	0.994
RS1	O15537-1.2	S95L	Pathogenic	0.999
RS1	O15537-1.2	S95M	Pathogenic	0.998
RS1	O15537-1.2	S95N	Pathogenic	0.97
RS1	O15537-1.2	S95P	Pathogenic	0.999
RS1	O15537-1.2	S95Q	Pathogenic	0.998
RS1	O15537-1.2	S95R	Pathogenic	0.999
RS1	O15537-1.2	S95T	Pathogenic	0.981
RS1	O15537-1.2	S95V	Pathogenic	1.0
RS1	O15537-1.2	S95W	Pathogenic	1.0
RS1	O15537-1.2	S95Y	Pathogenic	1.0
RS1	O15537-1.2	W96A	Pathogenic	1.0
RS1	O15537-1.2	W96C	Pathogenic	1.0
RS1	O15537-1.2	W96D	Pathogenic	1.0
RS1	O15537-1.2	W96E	Pathogenic	0.999
RS1	O15537-1.2	W96F	Pathogenic	0.978
RS1	O15537-1.2	W96G	Pathogenic	0.999
RS1	O15537-1.2	W96H	Pathogenic	0.998
RS1	O15537-1.2	W96I	Pathogenic	1.0
RS1	O15537-1.2	W96K	Pathogenic	0.997
RS1	O15537-1.2	W96L	Pathogenic	1.0
RS1	O15537-1.2	W96M	Pathogenic	0.999
RS1	O15537-1.2	W96N	Pathogenic	1.0
RS1	O15537-1.2	W96P	Pathogenic	1.0
RS1	O15537-1.2	W96Q	Pathogenic	0.997
RS1	O15537-1.2	W96R	Pathogenic	0.996
RS1	O15537-1.2	W96S	Pathogenic	1.0
RS1	O15537-1.2	W96T	Pathogenic	0.999
RS1	O15537-1.2	W96V	Pathogenic	1.0
RS1	O15537-1.2	W96Y	Pathogenic	0.554
RS1	O15537-1.2	T97A	Neutral	0.073
RS1	O15537-1.2	T97C	Neutral	0.091
RS1	O15537-1.2	T97D	Neutral	0.049
RS1	O15537-1.2	T97E	Neutral	0.076
RS1	O15537-1.2	T97F	Neutral	0.183
RS1	O15537-1.2	T97G	Pathogenic	0.743
RS1	O15537-1.2	T97H	Pathogenic	0.735
RS1	O15537-1.2	T97I	Neutral	0.028
RS1	O15537-1.2	T97K	Neutral	0.058
RS1	O15537-1.2	T97L	Neutral	0.034
RS1	O15537-1.2	T97M	Neutral	0.081
RS1	O15537-1.2	T97N	Neutral	0.011
RS1	O15537-1.2	T97P	Neutral	0.137
RS1	O15537-1.2	T97Q	Neutral	0.168
RS1	O15537-1.2	T97R	Neutral	0.068
RS1	O15537-1.2	T97S	Neutral	0.007
RS1	O15537-1.2	T97V	Neutral	0.01
RS1	O15537-1.2	T97W	Neutral	0.122
RS1	O15537-1.2	T97Y	Pathogenic	0.557
RS1	O15537-1.2	A98C	Neutral	0.222
RS1	O15537-1.2	A98D	Pathogenic	0.852
RS1	O15537-1.2	A98E	Pathogenic	0.604
RS1	O15537-1.2	A98F	Pathogenic	0.836
RS1	O15537-1.2	A98G	Neutral	0.37
RS1	O15537-1.2	A98H	Pathogenic	0.981
RS1	O15537-1.2	A98I	Neutral	0.394
RS1	O15537-1.2	A98K	Pathogenic	0.532
RS1	O15537-1.2	A98L	Neutral	0.443
RS1	O15537-1.2	A98M	Pathogenic	0.667
RS1	O15537-1.2	A98N	Pathogenic	0.897
RS1	O15537-1.2	A98P	Pathogenic	0.766
RS1	O15537-1.2	A98Q	Pathogenic	0.789
RS1	O15537-1.2	A98R	Pathogenic	0.573
RS1	O15537-1.2	A98S	Neutral	0.065
RS1	O15537-1.2	A98T	Pathogenic	0.52
RS1	O15537-1.2	A98V	Neutral	0.194
RS1	O15537-1.2	A98W	Pathogenic	0.953
RS1	O15537-1.2	A98Y	Pathogenic	0.966
RS1	O15537-1.2	N99A	Pathogenic	0.575
RS1	O15537-1.2	N99C	Pathogenic	0.634
RS1	O15537-1.2	N99D	Neutral	0.015
RS1	O15537-1.2	N99E	Neutral	0.125
RS1	O15537-1.2	N99F	Neutral	0.355
RS1	O15537-1.2	N99G	Neutral	0.074
RS1	O15537-1.2	N99H	Neutral	0.006
RS1	O15537-1.2	N99I	Neutral	0.311
RS1	O15537-1.2	N99K	Neutral	0.096
RS1	O15537-1.2	N99L	Neutral	0.356
RS1	O15537-1.2	N99M	Neutral	0.178
RS1	O15537-1.2	N99P	Neutral	0.298
RS1	O15537-1.2	N99Q	Neutral	0.073
RS1	O15537-1.2	N99R	Neutral	0.112
RS1	O15537-1.2	N99S	Neutral	0.009
RS1	O15537-1.2	N99T	Neutral	0.024
RS1	O15537-1.2	N99V	Pathogenic	0.518
RS1	O15537-1.2	N99W	Pathogenic	0.686
RS1	O15537-1.2	N99Y	Neutral	0.323
RS1	O15537-1.2	K100A	Pathogenic	0.993
RS1	O15537-1.2	K100C	Pathogenic	0.999
RS1	O15537-1.2	K100D	Pathogenic	0.999
RS1	O15537-1.2	K100E	Pathogenic	0.924
RS1	O15537-1.2	K100F	Pathogenic	0.992
RS1	O15537-1.2	K100G	Pathogenic	1.0
RS1	O15537-1.2	K100H	Pathogenic	0.99
RS1	O15537-1.2	K100I	Pathogenic	0.993
RS1	O15537-1.2	K100L	Pathogenic	0.963
RS1	O15537-1.2	K100M	Pathogenic	0.91
RS1	O15537-1.2	K100N	Pathogenic	0.989
RS1	O15537-1.2	K100P	Pathogenic	0.979
RS1	O15537-1.2	K100Q	Pathogenic	0.833
RS1	O15537-1.2	K100R	Pathogenic	0.752
RS1	O15537-1.2	K100S	Pathogenic	0.977
RS1	O15537-1.2	K100T	Pathogenic	0.991
RS1	O15537-1.2	K100V	Pathogenic	0.989
RS1	O15537-1.2	K100W	Pathogenic	0.987
RS1	O15537-1.2	K100Y	Pathogenic	0.99
RS1	O15537-1.2	A101C	Pathogenic	0.995
RS1	O15537-1.2	A101D	Pathogenic	1.0
RS1	O15537-1.2	A101E	Pathogenic	0.999
RS1	O15537-1.2	A101F	Pathogenic	1.0
RS1	O15537-1.2	A101G	Pathogenic	0.997
RS1	O15537-1.2	A101H	Pathogenic	1.0
RS1	O15537-1.2	A101I	Pathogenic	0.998
RS1	O15537-1.2	A101K	Pathogenic	0.999
RS1	O15537-1.2	A101L	Pathogenic	0.998
RS1	O15537-1.2	A101M	Pathogenic	0.999
RS1	O15537-1.2	A101N	Pathogenic	1.0
RS1	O15537-1.2	A101P	Pathogenic	1.0
RS1	O15537-1.2	A101Q	Pathogenic	1.0
RS1	O15537-1.2	A101R	Pathogenic	0.999
RS1	O15537-1.2	A101S	Pathogenic	0.979
RS1	O15537-1.2	A101T	Pathogenic	0.999
RS1	O15537-1.2	A101V	Pathogenic	0.994
RS1	O15537-1.2	A101W	Pathogenic	1.0
RS1	O15537-1.2	A101Y	Pathogenic	1.0
RS1	O15537-1.2	R102A	Pathogenic	0.998
RS1	O15537-1.2	R102C	Pathogenic	1.0
RS1	O15537-1.2	R102D	Pathogenic	1.0
RS1	O15537-1.2	R102E	Pathogenic	0.996
RS1	O15537-1.2	R102F	Pathogenic	0.998
RS1	O15537-1.2	R102G	Pathogenic	1.0
RS1	O15537-1.2	R102H	Pathogenic	0.982
RS1	O15537-1.2	R102I	Pathogenic	0.998
RS1	O15537-1.2	R102K	Pathogenic	0.902
RS1	O15537-1.2	R102L	Pathogenic	0.989
RS1	O15537-1.2	R102M	Pathogenic	0.973
RS1	O15537-1.2	R102N	Pathogenic	0.997
RS1	O15537-1.2	R102P	Pathogenic	0.999
RS1	O15537-1.2	R102Q	Pathogenic	0.947
RS1	O15537-1.2	R102S	Pathogenic	0.999
RS1	O15537-1.2	R102T	Pathogenic	0.998
RS1	O15537-1.2	R102V	Pathogenic	1.0
RS1	O15537-1.2	R102W	Pathogenic	0.994
RS1	O15537-1.2	R102Y	Pathogenic	0.997
RS1	O15537-1.2	L103A	Pathogenic	0.997
RS1	O15537-1.2	L103C	Pathogenic	0.999
RS1	O15537-1.2	L103D	Pathogenic	1.0
RS1	O15537-1.2	L103E	Pathogenic	0.999
RS1	O15537-1.2	L103F	Pathogenic	0.997
RS1	O15537-1.2	L103G	Pathogenic	1.0
RS1	O15537-1.2	L103H	Pathogenic	1.0
RS1	O15537-1.2	L103I	Pathogenic	0.869
RS1	O15537-1.2	L103K	Pathogenic	0.988
RS1	O15537-1.2	L103M	Pathogenic	0.764
RS1	O15537-1.2	L103N	Pathogenic	0.999
RS1	O15537-1.2	L103P	Pathogenic	1.0
RS1	O15537-1.2	L103Q	Pathogenic	0.997
RS1	O15537-1.2	L103R	Pathogenic	0.99
RS1	O15537-1.2	L103S	Pathogenic	0.999
RS1	O15537-1.2	L103T	Pathogenic	0.995
RS1	O15537-1.2	L103V	Pathogenic	0.964
RS1	O15537-1.2	L103W	Pathogenic	1.0
RS1	O15537-1.2	L103Y	Pathogenic	0.998
RS1	O15537-1.2	N104A	Pathogenic	1.0
RS1	O15537-1.2	N104C	Pathogenic	1.0
RS1	O15537-1.2	N104D	Pathogenic	0.962
RS1	O15537-1.2	N104E	Pathogenic	0.996
RS1	O15537-1.2	N104F	Pathogenic	0.999
RS1	O15537-1.2	N104G	Pathogenic	0.992
RS1	O15537-1.2	N104H	Pathogenic	0.914
RS1	O15537-1.2	N104I	Pathogenic	0.999
RS1	O15537-1.2	N104K	Pathogenic	0.994
RS1	O15537-1.2	N104L	Pathogenic	0.999
RS1	O15537-1.2	N104M	Pathogenic	0.997
RS1	O15537-1.2	N104P	Pathogenic	0.999
RS1	O15537-1.2	N104Q	Pathogenic	0.992
RS1	O15537-1.2	N104R	Pathogenic	0.995
RS1	O15537-1.2	N104S	Pathogenic	0.938
RS1	O15537-1.2	N104T	Pathogenic	0.976
RS1	O15537-1.2	N104V	Pathogenic	0.999
RS1	O15537-1.2	N104W	Pathogenic	1.0
RS1	O15537-1.2	N104Y	Pathogenic	0.999
RS1	O15537-1.2	S105A	Neutral	0.002
RS1	O15537-1.2	S105C	Neutral	0.02
RS1	O15537-1.2	S105D	Neutral	0.006
RS1	O15537-1.2	S105E	Neutral	0.01
RS1	O15537-1.2	S105F	Neutral	0.054
RS1	O15537-1.2	S105G	Neutral	0.026
RS1	O15537-1.2	S105H	Neutral	0.152
RS1	O15537-1.2	S105I	Neutral	0.045
RS1	O15537-1.2	S105K	Neutral	0.008
RS1	O15537-1.2	S105L	Neutral	0.054
RS1	O15537-1.2	S105M	Neutral	0.022
RS1	O15537-1.2	S105N	Neutral	0.001
RS1	O15537-1.2	S105P	Neutral	0.036
RS1	O15537-1.2	S105Q	Neutral	0.025
RS1	O15537-1.2	S105R	Neutral	0.055
RS1	O15537-1.2	S105T	Neutral	0.002
RS1	O15537-1.2	S105V	Neutral	0.1
RS1	O15537-1.2	S105W	Neutral	0.185
RS1	O15537-1.2	S105Y	Neutral	0.242
RS1	O15537-1.2	Q106A	Pathogenic	0.999
RS1	O15537-1.2	Q106C	Pathogenic	1.0
RS1	O15537-1.2	Q106D	Pathogenic	0.994
RS1	O15537-1.2	Q106E	Pathogenic	0.795
RS1	O15537-1.2	Q106F	Pathogenic	1.0
RS1	O15537-1.2	Q106G	Pathogenic	1.0
RS1	O15537-1.2	Q106H	Pathogenic	0.994
RS1	O15537-1.2	Q106I	Pathogenic	0.999
RS1	O15537-1.2	Q106K	Pathogenic	0.941
RS1	O15537-1.2	Q106L	Pathogenic	0.997
RS1	O15537-1.2	Q106M	Pathogenic	0.958
RS1	O15537-1.2	Q106N	Pathogenic	0.995
RS1	O15537-1.2	Q106P	Pathogenic	0.998
RS1	O15537-1.2	Q106R	Pathogenic	0.95
RS1	O15537-1.2	Q106S	Pathogenic	0.998
RS1	O15537-1.2	Q106T	Pathogenic	0.999
RS1	O15537-1.2	Q106V	Pathogenic	0.999
RS1	O15537-1.2	Q106W	Pathogenic	0.996
RS1	O15537-1.2	Q106Y	Pathogenic	0.997
RS1	O15537-1.2	G107A	Pathogenic	0.997
RS1	O15537-1.2	G107C	Pathogenic	1.0
RS1	O15537-1.2	G107D	Pathogenic	0.999
RS1	O15537-1.2	G107E	Pathogenic	1.0
RS1	O15537-1.2	G107F	Pathogenic	1.0
RS1	O15537-1.2	G107H	Pathogenic	1.0
RS1	O15537-1.2	G107I	Pathogenic	1.0
RS1	O15537-1.2	G107K	Pathogenic	1.0
RS1	O15537-1.2	G107L	Pathogenic	1.0
RS1	O15537-1.2	G107M	Pathogenic	1.0
RS1	O15537-1.2	G107N	Pathogenic	0.997
RS1	O15537-1.2	G107P	Pathogenic	1.0
RS1	O15537-1.2	G107Q	Pathogenic	1.0
RS1	O15537-1.2	G107R	Pathogenic	1.0
RS1	O15537-1.2	G107S	Pathogenic	0.999
RS1	O15537-1.2	G107T	Pathogenic	1.0
RS1	O15537-1.2	G107V	Pathogenic	1.0
RS1	O15537-1.2	G107W	Pathogenic	0.999
RS1	O15537-1.2	G107Y	Pathogenic	1.0
RS1	O15537-1.2	F108A	Pathogenic	0.998
RS1	O15537-1.2	F108C	Pathogenic	0.999
RS1	O15537-1.2	F108D	Pathogenic	0.997
RS1	O15537-1.2	F108E	Pathogenic	0.997
RS1	O15537-1.2	F108G	Pathogenic	1.0
RS1	O15537-1.2	F108H	Pathogenic	0.967
RS1	O15537-1.2	F108I	Pathogenic	0.991
RS1	O15537-1.2	F108K	Pathogenic	0.991
RS1	O15537-1.2	F108L	Pathogenic	0.989
RS1	O15537-1.2	F108M	Pathogenic	0.973
RS1	O15537-1.2	F108N	Pathogenic	0.998
RS1	O15537-1.2	F108P	Pathogenic	1.0
RS1	O15537-1.2	F108Q	Pathogenic	0.998
RS1	O15537-1.2	F108R	Pathogenic	0.992
RS1	O15537-1.2	F108S	Pathogenic	0.996
RS1	O15537-1.2	F108T	Pathogenic	0.997
RS1	O15537-1.2	F108V	Pathogenic	0.997
RS1	O15537-1.2	F108W	Pathogenic	0.899
RS1	O15537-1.2	F108Y	Neutral	0.07
RS1	O15537-1.2	G109A	Pathogenic	0.997
RS1	O15537-1.2	G109C	Pathogenic	1.0
RS1	O15537-1.2	G109D	Pathogenic	0.999
RS1	O15537-1.2	G109E	Pathogenic	1.0
RS1	O15537-1.2	G109F	Pathogenic	1.0
RS1	O15537-1.2	G109H	Pathogenic	1.0
RS1	O15537-1.2	G109I	Pathogenic	1.0
RS1	O15537-1.2	G109K	Pathogenic	1.0
RS1	O15537-1.2	G109L	Pathogenic	1.0
RS1	O15537-1.2	G109M	Pathogenic	1.0
RS1	O15537-1.2	G109N	Pathogenic	0.997
RS1	O15537-1.2	G109P	Pathogenic	1.0
RS1	O15537-1.2	G109Q	Pathogenic	1.0
RS1	O15537-1.2	G109R	Pathogenic	1.0
RS1	O15537-1.2	G109S	Pathogenic	0.999
RS1	O15537-1.2	G109T	Pathogenic	1.0
RS1	O15537-1.2	G109V	Pathogenic	1.0
RS1	O15537-1.2	G109W	Pathogenic	0.999
RS1	O15537-1.2	G109Y	Pathogenic	1.0
RS1	O15537-1.2	C110A	Pathogenic	1.0
RS1	O15537-1.2	C110D	Pathogenic	1.0
RS1	O15537-1.2	C110E	Pathogenic	1.0
RS1	O15537-1.2	C110F	Pathogenic	1.0
RS1	O15537-1.2	C110G	Pathogenic	1.0
RS1	O15537-1.2	C110H	Pathogenic	1.0
RS1	O15537-1.2	C110I	Pathogenic	1.0
RS1	O15537-1.2	C110K	Pathogenic	1.0
RS1	O15537-1.2	C110L	Pathogenic	1.0
RS1	O15537-1.2	C110M	Pathogenic	1.0
RS1	O15537-1.2	C110N	Pathogenic	1.0
RS1	O15537-1.2	C110P	Pathogenic	1.0
RS1	O15537-1.2	C110Q	Pathogenic	1.0
RS1	O15537-1.2	C110R	Pathogenic	1.0
RS1	O15537-1.2	C110S	Pathogenic	1.0
RS1	O15537-1.2	C110T	Pathogenic	1.0
RS1	O15537-1.2	C110V	Pathogenic	1.0
RS1	O15537-1.2	C110W	Pathogenic	1.0
RS1	O15537-1.2	C110Y	Pathogenic	1.0
RS1	O15537-1.2	A111C	Pathogenic	0.977
RS1	O15537-1.2	A111D	Pathogenic	0.999
RS1	O15537-1.2	A111E	Pathogenic	0.996
RS1	O15537-1.2	A111F	Pathogenic	0.999
RS1	O15537-1.2	A111G	Pathogenic	0.989
RS1	O15537-1.2	A111H	Pathogenic	1.0
RS1	O15537-1.2	A111I	Pathogenic	0.99
RS1	O15537-1.2	A111K	Pathogenic	0.994
RS1	O15537-1.2	A111L	Pathogenic	0.992
RS1	O15537-1.2	A111M	Pathogenic	0.997
RS1	O15537-1.2	A111N	Pathogenic	0.999
RS1	O15537-1.2	A111P	Pathogenic	0.998
RS1	O15537-1.2	A111Q	Pathogenic	0.998
RS1	O15537-1.2	A111R	Pathogenic	0.995
RS1	O15537-1.2	A111S	Pathogenic	0.913
RS1	O15537-1.2	A111T	Pathogenic	0.994
RS1	O15537-1.2	A111V	Pathogenic	0.973
RS1	O15537-1.2	A111W	Pathogenic	1.0
RS1	O15537-1.2	A111Y	Pathogenic	1.0
RS1	O15537-1.2	W112A	Pathogenic	1.0
RS1	O15537-1.2	W112C	Pathogenic	0.999
RS1	O15537-1.2	W112D	Pathogenic	0.999
RS1	O15537-1.2	W112E	Pathogenic	0.994
RS1	O15537-1.2	W112F	Pathogenic	0.893
RS1	O15537-1.2	W112G	Pathogenic	0.996
RS1	O15537-1.2	W112H	Pathogenic	0.991
RS1	O15537-1.2	W112I	Pathogenic	1.0
RS1	O15537-1.2	W112K	Pathogenic	0.984
RS1	O15537-1.2	W112L	Pathogenic	1.0
RS1	O15537-1.2	W112M	Pathogenic	0.993
RS1	O15537-1.2	W112N	Pathogenic	0.999
RS1	O15537-1.2	W112P	Pathogenic	1.0
RS1	O15537-1.2	W112Q	Pathogenic	0.983
RS1	O15537-1.2	W112R	Pathogenic	0.98
RS1	O15537-1.2	W112S	Pathogenic	0.999
RS1	O15537-1.2	W112T	Pathogenic	0.995
RS1	O15537-1.2	W112V	Pathogenic	1.0
RS1	O15537-1.2	W112Y	Neutral	0.188
RS1	O15537-1.2	L113A	Pathogenic	0.998
RS1	O15537-1.2	L113C	Pathogenic	0.999
RS1	O15537-1.2	L113D	Pathogenic	1.0
RS1	O15537-1.2	L113E	Pathogenic	0.999
RS1	O15537-1.2	L113F	Pathogenic	0.998
RS1	O15537-1.2	L113G	Pathogenic	1.0
RS1	O15537-1.2	L113H	Pathogenic	1.0
RS1	O15537-1.2	L113I	Pathogenic	0.915
RS1	O15537-1.2	L113K	Pathogenic	0.993
RS1	O15537-1.2	L113M	Pathogenic	0.84
RS1	O15537-1.2	L113N	Pathogenic	1.0
RS1	O15537-1.2	L113P	Pathogenic	1.0
RS1	O15537-1.2	L113Q	Pathogenic	0.998
RS1	O15537-1.2	L113R	Pathogenic	0.994
RS1	O15537-1.2	L113S	Pathogenic	0.999
RS1	O15537-1.2	L113T	Pathogenic	0.997
RS1	O15537-1.2	L113V	Pathogenic	0.978
RS1	O15537-1.2	L113W	Pathogenic	1.0
RS1	O15537-1.2	L113Y	Pathogenic	0.999
RS1	O15537-1.2	S114A	Pathogenic	0.865
RS1	O15537-1.2	S114C	Pathogenic	0.987
RS1	O15537-1.2	S114D	Pathogenic	0.958
RS1	O15537-1.2	S114E	Pathogenic	0.975
RS1	O15537-1.2	S114F	Pathogenic	0.995
RS1	O15537-1.2	S114G	Pathogenic	0.99
RS1	O15537-1.2	S114H	Pathogenic	0.999
RS1	O15537-1.2	S114I	Pathogenic	0.994
RS1	O15537-1.2	S114K	Pathogenic	0.967
RS1	O15537-1.2	S114L	Pathogenic	0.995
RS1	O15537-1.2	S114M	Pathogenic	0.988
RS1	O15537-1.2	S114N	Pathogenic	0.843
RS1	O15537-1.2	S114P	Pathogenic	0.993
RS1	O15537-1.2	S114Q	Pathogenic	0.99
RS1	O15537-1.2	S114R	Pathogenic	0.996
RS1	O15537-1.2	S114T	Pathogenic	0.898
RS1	O15537-1.2	S114V	Pathogenic	0.998
RS1	O15537-1.2	S114W	Pathogenic	0.999
RS1	O15537-1.2	S114Y	Pathogenic	0.999
RS1	O15537-1.2	K115A	Pathogenic	0.985
RS1	O15537-1.2	K115C	Pathogenic	0.998
RS1	O15537-1.2	K115D	Pathogenic	0.997
RS1	O15537-1.2	K115E	Pathogenic	0.843
RS1	O15537-1.2	K115F	Pathogenic	0.981
RS1	O15537-1.2	K115G	Pathogenic	0.999
RS1	O15537-1.2	K115H	Pathogenic	0.977
RS1	O15537-1.2	K115I	Pathogenic	0.984
RS1	O15537-1.2	K115L	Pathogenic	0.919
RS1	O15537-1.2	K115M	Pathogenic	0.817
RS1	O15537-1.2	K115N	Pathogenic	0.975
RS1	O15537-1.2	K115P	Pathogenic	0.953
RS1	O15537-1.2	K115Q	Pathogenic	0.686
RS1	O15537-1.2	K115R	Pathogenic	0.57
RS1	O15537-1.2	K115S	Pathogenic	0.948
RS1	O15537-1.2	K115T	Pathogenic	0.98
RS1	O15537-1.2	K115V	Pathogenic	0.975
RS1	O15537-1.2	K115W	Pathogenic	0.97
RS1	O15537-1.2	K115Y	Pathogenic	0.978
RS1	O15537-1.2	F116A	Pathogenic	0.531
RS1	O15537-1.2	F116C	Pathogenic	0.762
RS1	O15537-1.2	F116D	Neutral	0.378
RS1	O15537-1.2	F116E	Neutral	0.374
RS1	O15537-1.2	F116G	Pathogenic	0.842
RS1	O15537-1.2	F116H	Neutral	0.054
RS1	O15537-1.2	F116I	Neutral	0.171
RS1	O15537-1.2	F116K	Neutral	0.168
RS1	O15537-1.2	F116L	Neutral	0.151
RS1	O15537-1.2	F116M	Neutral	0.066
RS1	O15537-1.2	F116N	Neutral	0.439
RS1	O15537-1.2	F116P	Pathogenic	0.987
RS1	O15537-1.2	F116Q	Pathogenic	0.558
RS1	O15537-1.2	F116R	Neutral	0.193
RS1	O15537-1.2	F116S	Neutral	0.344
RS1	O15537-1.2	F116T	Neutral	0.408
RS1	O15537-1.2	F116V	Neutral	0.372
RS1	O15537-1.2	F116W	Neutral	0.017
RS1	O15537-1.2	F116Y	Neutral	0.0
RS1	O15537-1.2	Q117A	Pathogenic	0.929
RS1	O15537-1.2	Q117C	Pathogenic	0.991
RS1	O15537-1.2	Q117D	Pathogenic	0.576
RS1	O15537-1.2	Q117E	Neutral	0.031
RS1	O15537-1.2	Q117F	Pathogenic	0.952
RS1	O15537-1.2	Q117G	Pathogenic	0.995
RS1	O15537-1.2	Q117H	Pathogenic	0.6
RS1	O15537-1.2	Q117I	Pathogenic	0.942
RS1	O15537-1.2	Q117K	Neutral	0.117
RS1	O15537-1.2	Q117L	Pathogenic	0.757
RS1	O15537-1.2	Q117M	Neutral	0.159
RS1	O15537-1.2	Q117N	Pathogenic	0.637
RS1	O15537-1.2	Q117P	Pathogenic	0.805
RS1	O15537-1.2	Q117R	Neutral	0.136
RS1	O15537-1.2	Q117S	Pathogenic	0.786
RS1	O15537-1.2	Q117T	Pathogenic	0.907
RS1	O15537-1.2	Q117V	Pathogenic	0.888
RS1	O15537-1.2	Q117W	Pathogenic	0.656
RS1	O15537-1.2	Q117Y	Pathogenic	0.729
RS1	O15537-1.2	D118A	Pathogenic	0.999
RS1	O15537-1.2	D118C	Pathogenic	0.999
RS1	O15537-1.2	D118E	Pathogenic	0.83
RS1	O15537-1.2	D118F	Pathogenic	0.999
RS1	O15537-1.2	D118G	Pathogenic	0.998
RS1	O15537-1.2	D118H	Pathogenic	0.997
RS1	O15537-1.2	D118I	Pathogenic	0.998
RS1	O15537-1.2	D118K	Pathogenic	0.999
RS1	O15537-1.2	D118L	Pathogenic	1.0
RS1	O15537-1.2	D118M	Pathogenic	0.999
RS1	O15537-1.2	D118N	Pathogenic	0.96
RS1	O15537-1.2	D118P	Pathogenic	0.986
RS1	O15537-1.2	D118Q	Pathogenic	0.99
RS1	O15537-1.2	D118R	Pathogenic	1.0
RS1	O15537-1.2	D118S	Pathogenic	0.984
RS1	O15537-1.2	D118T	Pathogenic	0.994
RS1	O15537-1.2	D118V	Pathogenic	0.999
RS1	O15537-1.2	D118W	Pathogenic	1.0
RS1	O15537-1.2	D118Y	Pathogenic	1.0
RS1	O15537-1.2	S119A	Neutral	0.0
RS1	O15537-1.2	S119C	Neutral	0.003
RS1	O15537-1.2	S119D	Neutral	0.001
RS1	O15537-1.2	S119E	Neutral	0.001
RS1	O15537-1.2	S119F	Neutral	0.007
RS1	O15537-1.2	S119G	Neutral	0.003
RS1	O15537-1.2	S119H	Neutral	0.023
RS1	O15537-1.2	S119I	Neutral	0.006
RS1	O15537-1.2	S119K	Neutral	0.001
RS1	O15537-1.2	S119L	Neutral	0.007
RS1	O15537-1.2	S119M	Neutral	0.003
RS1	O15537-1.2	S119N	Neutral	0.0
RS1	O15537-1.2	S119P	Neutral	0.005
RS1	O15537-1.2	S119Q	Neutral	0.003
RS1	O15537-1.2	S119R	Neutral	0.008
RS1	O15537-1.2	S119T	Neutral	0.0
RS1	O15537-1.2	S119V	Neutral	0.014
RS1	O15537-1.2	S119W	Neutral	0.028
RS1	O15537-1.2	S119Y	Neutral	0.04
RS1	O15537-1.2	S120A	Neutral	0.0
RS1	O15537-1.2	S120C	Neutral	0.0
RS1	O15537-1.2	S120D	Neutral	0.0
RS1	O15537-1.2	S120E	Neutral	0.0
RS1	O15537-1.2	S120F	Neutral	0.0
RS1	O15537-1.2	S120G	Neutral	0.0
RS1	O15537-1.2	S120H	Neutral	0.001
RS1	O15537-1.2	S120I	Neutral	0.0
RS1	O15537-1.2	S120K	Neutral	0.0
RS1	O15537-1.2	S120L	Neutral	0.0
RS1	O15537-1.2	S120M	Neutral	0.0
RS1	O15537-1.2	S120N	Neutral	0.0
RS1	O15537-1.2	S120P	Neutral	0.0
RS1	O15537-1.2	S120Q	Neutral	0.0
RS1	O15537-1.2	S120R	Neutral	0.0
RS1	O15537-1.2	S120T	Neutral	0.0
RS1	O15537-1.2	S120V	Neutral	0.0
RS1	O15537-1.2	S120W	Neutral	0.001
RS1	O15537-1.2	S120Y	Neutral	0.001
RS1	O15537-1.2	Q121A	Pathogenic	0.999
RS1	O15537-1.2	Q121C	Pathogenic	1.0
RS1	O15537-1.2	Q121D	Pathogenic	0.994
RS1	O15537-1.2	Q121E	Pathogenic	0.81
RS1	O15537-1.2	Q121F	Pathogenic	1.0
RS1	O15537-1.2	Q121G	Pathogenic	1.0
RS1	O15537-1.2	Q121H	Pathogenic	0.995
RS1	O15537-1.2	Q121I	Pathogenic	1.0
RS1	O15537-1.2	Q121K	Pathogenic	0.946
RS1	O15537-1.2	Q121L	Pathogenic	0.998
RS1	O15537-1.2	Q121M	Pathogenic	0.961
RS1	O15537-1.2	Q121N	Pathogenic	0.996
RS1	O15537-1.2	Q121P	Pathogenic	0.998
RS1	O15537-1.2	Q121R	Pathogenic	0.954
RS1	O15537-1.2	Q121S	Pathogenic	0.998
RS1	O15537-1.2	Q121T	Pathogenic	0.999
RS1	O15537-1.2	Q121V	Pathogenic	0.999
RS1	O15537-1.2	Q121W	Pathogenic	0.996
RS1	O15537-1.2	Q121Y	Pathogenic	0.997
RS1	O15537-1.2	W122A	Pathogenic	1.0
RS1	O15537-1.2	W122C	Pathogenic	0.999
RS1	O15537-1.2	W122D	Pathogenic	1.0
RS1	O15537-1.2	W122E	Pathogenic	0.997
RS1	O15537-1.2	W122F	Pathogenic	0.942
RS1	O15537-1.2	W122G	Pathogenic	0.998
RS1	O15537-1.2	W122H	Pathogenic	0.995
RS1	O15537-1.2	W122I	Pathogenic	1.0
RS1	O15537-1.2	W122K	Pathogenic	0.992
RS1	O15537-1.2	W122L	Pathogenic	1.0
RS1	O15537-1.2	W122M	Pathogenic	0.996
RS1	O15537-1.2	W122N	Pathogenic	1.0
RS1	O15537-1.2	W122P	Pathogenic	1.0
RS1	O15537-1.2	W122Q	Pathogenic	0.991
RS1	O15537-1.2	W122R	Pathogenic	0.989
RS1	O15537-1.2	W122S	Pathogenic	0.999
RS1	O15537-1.2	W122T	Pathogenic	0.997
RS1	O15537-1.2	W122V	Pathogenic	1.0
RS1	O15537-1.2	W122Y	Neutral	0.31
RS1	O15537-1.2	L123A	Neutral	0.45
RS1	O15537-1.2	L123C	Pathogenic	0.698
RS1	O15537-1.2	L123D	Pathogenic	0.948
RS1	O15537-1.2	L123E	Pathogenic	0.735
RS1	O15537-1.2	L123F	Neutral	0.451
RS1	O15537-1.2	L123G	Pathogenic	0.994
RS1	O15537-1.2	L123H	Pathogenic	0.917
RS1	O15537-1.2	L123I	Neutral	0.016
RS1	O15537-1.2	L123K	Neutral	0.169
RS1	O15537-1.2	L123M	Neutral	0.008
RS1	O15537-1.2	L123N	Pathogenic	0.784
RS1	O15537-1.2	L123P	Pathogenic	0.982
RS1	O15537-1.2	L123Q	Neutral	0.476
RS1	O15537-1.2	L123R	Neutral	0.194
RS1	O15537-1.2	L123S	Pathogenic	0.709
RS1	O15537-1.2	L123T	Neutral	0.332
RS1	O15537-1.2	L123V	Neutral	0.062
RS1	O15537-1.2	L123W	Pathogenic	0.954
RS1	O15537-1.2	L123Y	Pathogenic	0.616
RS1	O15537-1.2	Q124A	Pathogenic	0.998
RS1	O15537-1.2	Q124C	Pathogenic	1.0
RS1	O15537-1.2	Q124D	Pathogenic	0.976
RS1	O15537-1.2	Q124E	Neutral	0.497
RS1	O15537-1.2	Q124F	Pathogenic	0.998
RS1	O15537-1.2	Q124G	Pathogenic	1.0
RS1	O15537-1.2	Q124H	Pathogenic	0.979
RS1	O15537-1.2	Q124I	Pathogenic	0.998
RS1	O15537-1.2	Q124K	Pathogenic	0.802
RS1	O15537-1.2	Q124L	Pathogenic	0.99
RS1	O15537-1.2	Q124M	Pathogenic	0.852
RS1	O15537-1.2	Q124N	Pathogenic	0.982
RS1	O15537-1.2	Q124P	Pathogenic	0.992
RS1	O15537-1.2	Q124R	Pathogenic	0.828
RS1	O15537-1.2	Q124S	Pathogenic	0.991
RS1	O15537-1.2	Q124T	Pathogenic	0.997
RS1	O15537-1.2	Q124V	Pathogenic	0.996
RS1	O15537-1.2	Q124W	Pathogenic	0.983
RS1	O15537-1.2	Q124Y	Pathogenic	0.988
RS1	O15537-1.2	I125A	Pathogenic	0.956
RS1	O15537-1.2	I125C	Pathogenic	0.984
RS1	O15537-1.2	I125D	Pathogenic	0.987
RS1	O15537-1.2	I125E	Pathogenic	0.987
RS1	O15537-1.2	I125F	Pathogenic	0.969
RS1	O15537-1.2	I125G	Pathogenic	1.0
RS1	O15537-1.2	I125H	Pathogenic	0.997
RS1	O15537-1.2	I125K	Pathogenic	0.972
RS1	O15537-1.2	I125L	Neutral	0.349
RS1	O15537-1.2	I125M	Pathogenic	0.578
RS1	O15537-1.2	I125N	Pathogenic	0.99
RS1	O15537-1.2	I125P	Pathogenic	0.999
RS1	O15537-1.2	I125Q	Pathogenic	0.994
RS1	O15537-1.2	I125R	Pathogenic	0.976
RS1	O15537-1.2	I125S	Pathogenic	0.985
RS1	O15537-1.2	I125T	Pathogenic	0.93
RS1	O15537-1.2	I125V	Neutral	0.041
RS1	O15537-1.2	I125W	Pathogenic	1.0
RS1	O15537-1.2	I125Y	Pathogenic	0.977
RS1	O15537-1.2	D126A	Pathogenic	0.999
RS1	O15537-1.2	D126C	Pathogenic	0.999
RS1	O15537-1.2	D126E	Pathogenic	0.753
RS1	O15537-1.2	D126F	Pathogenic	0.998
RS1	O15537-1.2	D126G	Pathogenic	0.997
RS1	O15537-1.2	D126H	Pathogenic	0.995
RS1	O15537-1.2	D126I	Pathogenic	0.997
RS1	O15537-1.2	D126K	Pathogenic	0.999
RS1	O15537-1.2	D126L	Pathogenic	1.0
RS1	O15537-1.2	D126M	Pathogenic	0.999
RS1	O15537-1.2	D126N	Pathogenic	0.937
RS1	O15537-1.2	D126P	Pathogenic	0.977
RS1	O15537-1.2	D126Q	Pathogenic	0.984
RS1	O15537-1.2	D126R	Pathogenic	1.0
RS1	O15537-1.2	D126S	Pathogenic	0.975
RS1	O15537-1.2	D126T	Pathogenic	0.991
RS1	O15537-1.2	D126V	Pathogenic	0.999
RS1	O15537-1.2	D126W	Pathogenic	0.999
RS1	O15537-1.2	D126Y	Pathogenic	1.0
RS1	O15537-1.2	L127A	Pathogenic	0.982
RS1	O15537-1.2	L127C	Pathogenic	0.994
RS1	O15537-1.2	L127D	Pathogenic	0.999
RS1	O15537-1.2	L127E	Pathogenic	0.995
RS1	O15537-1.2	L127F	Pathogenic	0.982
RS1	O15537-1.2	L127G	Pathogenic	1.0
RS1	O15537-1.2	L127H	Pathogenic	0.999
RS1	O15537-1.2	L127I	Pathogenic	0.523
RS1	O15537-1.2	L127K	Pathogenic	0.931
RS1	O15537-1.2	L127M	Neutral	0.347
RS1	O15537-1.2	L127N	Pathogenic	0.996
RS1	O15537-1.2	L127P	Pathogenic	1.0
RS1	O15537-1.2	L127Q	Pathogenic	0.984
RS1	O15537-1.2	L127R	Pathogenic	0.941
RS1	O15537-1.2	L127S	Pathogenic	0.994
RS1	O15537-1.2	L127T	Pathogenic	0.971
RS1	O15537-1.2	L127V	Pathogenic	0.816
RS1	O15537-1.2	L127W	Pathogenic	0.999
RS1	O15537-1.2	L127Y	Pathogenic	0.991
RS1	O15537-1.2	K128A	Pathogenic	0.687
RS1	O15537-1.2	K128C	Pathogenic	0.947
RS1	O15537-1.2	K128D	Pathogenic	0.927
RS1	O15537-1.2	K128E	Neutral	0.153
RS1	O15537-1.2	K128F	Pathogenic	0.637
RS1	O15537-1.2	K128G	Pathogenic	0.972
RS1	O15537-1.2	K128H	Pathogenic	0.588
RS1	O15537-1.2	K128I	Pathogenic	0.668
RS1	O15537-1.2	K128L	Neutral	0.277
RS1	O15537-1.2	K128M	Neutral	0.13
RS1	O15537-1.2	K128N	Pathogenic	0.568
RS1	O15537-1.2	K128P	Neutral	0.408
RS1	O15537-1.2	K128Q	Neutral	0.068
RS1	O15537-1.2	K128R	Neutral	0.043
RS1	O15537-1.2	K128S	Neutral	0.38
RS1	O15537-1.2	K128T	Pathogenic	0.621
RS1	O15537-1.2	K128V	Pathogenic	0.57
RS1	O15537-1.2	K128W	Pathogenic	0.519
RS1	O15537-1.2	K128Y	Pathogenic	0.604
RS1	O15537-1.2	E129A	Pathogenic	0.951
RS1	O15537-1.2	E129C	Pathogenic	0.999
RS1	O15537-1.2	E129D	Neutral	0.201
RS1	O15537-1.2	E129F	Pathogenic	0.972
RS1	O15537-1.2	E129G	Pathogenic	0.997
RS1	O15537-1.2	E129H	Pathogenic	0.721
RS1	O15537-1.2	E129I	Pathogenic	0.966
RS1	O15537-1.2	E129K	Pathogenic	0.542
RS1	O15537-1.2	E129L	Pathogenic	0.972
RS1	O15537-1.2	E129M	Pathogenic	0.931
RS1	O15537-1.2	E129N	Pathogenic	0.921
RS1	O15537-1.2	E129P	Pathogenic	0.859
RS1	O15537-1.2	E129Q	Neutral	0.105
RS1	O15537-1.2	E129R	Pathogenic	0.9
RS1	O15537-1.2	E129S	Pathogenic	0.844
RS1	O15537-1.2	E129T	Pathogenic	0.935
RS1	O15537-1.2	E129V	Pathogenic	0.921
RS1	O15537-1.2	E129W	Pathogenic	0.955
RS1	O15537-1.2	E129Y	Pathogenic	0.967
RS1	O15537-1.2	I130A	Neutral	0.018
RS1	O15537-1.2	I130C	Neutral	0.05
RS1	O15537-1.2	I130D	Neutral	0.061
RS1	O15537-1.2	I130E	Neutral	0.06
RS1	O15537-1.2	I130F	Neutral	0.026
RS1	O15537-1.2	I130G	Pathogenic	0.784
RS1	O15537-1.2	I130H	Neutral	0.202
RS1	O15537-1.2	I130K	Neutral	0.029
RS1	O15537-1.2	I130L	Neutral	0.0
RS1	O15537-1.2	I130M	Neutral	0.001
RS1	O15537-1.2	I130N	Neutral	0.077
RS1	O15537-1.2	I130P	Pathogenic	0.551
RS1	O15537-1.2	I130Q	Neutral	0.119
RS1	O15537-1.2	I130R	Neutral	0.034
RS1	O15537-1.2	I130S	Neutral	0.053
RS1	O15537-1.2	I130T	Neutral	0.011
RS1	O15537-1.2	I130V	Neutral	0.0
RS1	O15537-1.2	I130W	Pathogenic	0.822
RS1	O15537-1.2	I130Y	Neutral	0.036
RS1	O15537-1.2	K131A	Neutral	0.013
RS1	O15537-1.2	K131C	Neutral	0.1
RS1	O15537-1.2	K131D	Neutral	0.073
RS1	O15537-1.2	K131E	Neutral	0.001
RS1	O15537-1.2	K131F	Neutral	0.011
RS1	O15537-1.2	K131G	Neutral	0.176
RS1	O15537-1.2	K131H	Neutral	0.009
RS1	O15537-1.2	K131I	Neutral	0.012
RS1	O15537-1.2	K131L	Neutral	0.002
RS1	O15537-1.2	K131M	Neutral	0.001
RS1	O15537-1.2	K131N	Neutral	0.008
RS1	O15537-1.2	K131P	Neutral	0.004
RS1	O15537-1.2	K131Q	Neutral	0.0
RS1	O15537-1.2	K131R	Neutral	0.0
RS1	O15537-1.2	K131S	Neutral	0.004
RS1	O15537-1.2	K131T	Neutral	0.01
RS1	O15537-1.2	K131V	Neutral	0.008
RS1	O15537-1.2	K131W	Neutral	0.007
RS1	O15537-1.2	K131Y	Neutral	0.009
RS1	O15537-1.2	V132A	Pathogenic	0.6
RS1	O15537-1.2	V132C	Pathogenic	0.965
RS1	O15537-1.2	V132D	Pathogenic	0.971
RS1	O15537-1.2	V132E	Pathogenic	0.852
RS1	O15537-1.2	V132F	Pathogenic	0.943
RS1	O15537-1.2	V132G	Pathogenic	0.997
RS1	O15537-1.2	V132H	Pathogenic	0.995
RS1	O15537-1.2	V132I	Neutral	0.008
RS1	O15537-1.2	V132K	Pathogenic	0.811
RS1	O15537-1.2	V132L	Neutral	0.288
RS1	O15537-1.2	V132M	Pathogenic	0.504
RS1	O15537-1.2	V132N	Pathogenic	0.977
RS1	O15537-1.2	V132P	Pathogenic	0.99
RS1	O15537-1.2	V132Q	Pathogenic	0.934
RS1	O15537-1.2	V132R	Pathogenic	0.97
RS1	O15537-1.2	V132S	Pathogenic	0.966
RS1	O15537-1.2	V132T	Neutral	0.478
RS1	O15537-1.2	V132W	Pathogenic	0.998
RS1	O15537-1.2	V132Y	Pathogenic	0.971
RS1	O15537-1.2	I133A	Neutral	0.093
RS1	O15537-1.2	I133C	Neutral	0.225
RS1	O15537-1.2	I133D	Neutral	0.262
RS1	O15537-1.2	I133E	Neutral	0.259
RS1	O15537-1.2	I133F	Neutral	0.128
RS1	O15537-1.2	I133G	Pathogenic	0.952
RS1	O15537-1.2	I133H	Pathogenic	0.581
RS1	O15537-1.2	I133K	Neutral	0.141
RS1	O15537-1.2	I133L	Neutral	0.003
RS1	O15537-1.2	I133M	Neutral	0.006
RS1	O15537-1.2	I133N	Neutral	0.314
RS1	O15537-1.2	I133P	Pathogenic	0.871
RS1	O15537-1.2	I133Q	Neutral	0.425
RS1	O15537-1.2	I133R	Neutral	0.163
RS1	O15537-1.2	I133S	Neutral	0.235
RS1	O15537-1.2	I133T	Neutral	0.059
RS1	O15537-1.2	I133V	Neutral	0.0
RS1	O15537-1.2	I133W	Pathogenic	0.962
RS1	O15537-1.2	I133Y	Neutral	0.168
RS1	O15537-1.2	S134A	Pathogenic	0.927
RS1	O15537-1.2	S134C	Pathogenic	0.994
RS1	O15537-1.2	S134D	Pathogenic	0.978
RS1	O15537-1.2	S134E	Pathogenic	0.987
RS1	O15537-1.2	S134F	Pathogenic	0.998
RS1	O15537-1.2	S134G	Pathogenic	0.995
RS1	O15537-1.2	S134H	Pathogenic	0.999
RS1	O15537-1.2	S134I	Pathogenic	0.997
RS1	O15537-1.2	S134K	Pathogenic	0.983
RS1	O15537-1.2	S134L	Pathogenic	0.998
RS1	O15537-1.2	S134M	Pathogenic	0.994
RS1	O15537-1.2	S134N	Pathogenic	0.914
RS1	O15537-1.2	S134P	Pathogenic	0.996
RS1	O15537-1.2	S134Q	Pathogenic	0.995
RS1	O15537-1.2	S134R	Pathogenic	0.998
RS1	O15537-1.2	S134T	Pathogenic	0.945
RS1	O15537-1.2	S134V	Pathogenic	0.999
RS1	O15537-1.2	S134W	Pathogenic	0.999
RS1	O15537-1.2	S134Y	Pathogenic	1.0
RS1	O15537-1.2	G135A	Pathogenic	0.982
RS1	O15537-1.2	G135C	Pathogenic	1.0
RS1	O15537-1.2	G135D	Pathogenic	0.995
RS1	O15537-1.2	G135E	Pathogenic	1.0
RS1	O15537-1.2	G135F	Pathogenic	1.0
RS1	O15537-1.2	G135H	Pathogenic	1.0
RS1	O15537-1.2	G135I	Pathogenic	1.0
RS1	O15537-1.2	G135K	Pathogenic	0.999
RS1	O15537-1.2	G135L	Pathogenic	1.0
RS1	O15537-1.2	G135M	Pathogenic	1.0
RS1	O15537-1.2	G135N	Pathogenic	0.979
RS1	O15537-1.2	G135P	Pathogenic	0.999
RS1	O15537-1.2	G135Q	Pathogenic	1.0
RS1	O15537-1.2	G135R	Pathogenic	0.999
RS1	O15537-1.2	G135S	Pathogenic	0.99
RS1	O15537-1.2	G135T	Pathogenic	1.0
RS1	O15537-1.2	G135V	Pathogenic	1.0
RS1	O15537-1.2	G135W	Pathogenic	0.995
RS1	O15537-1.2	G135Y	Pathogenic	1.0
RS1	O15537-1.2	I136A	Pathogenic	0.84
RS1	O15537-1.2	I136C	Pathogenic	0.937
RS1	O15537-1.2	I136D	Pathogenic	0.947
RS1	O15537-1.2	I136E	Pathogenic	0.947
RS1	O15537-1.2	I136F	Pathogenic	0.882
RS1	O15537-1.2	I136G	Pathogenic	0.999
RS1	O15537-1.2	I136H	Pathogenic	0.986
RS1	O15537-1.2	I136K	Pathogenic	0.893
RS1	O15537-1.2	I136L	Neutral	0.114
RS1	O15537-1.2	I136M	Neutral	0.247
RS1	O15537-1.2	I136N	Pathogenic	0.959
RS1	O15537-1.2	I136P	Pathogenic	0.997
RS1	O15537-1.2	I136Q	Pathogenic	0.974
RS1	O15537-1.2	I136R	Pathogenic	0.908
RS1	O15537-1.2	I136S	Pathogenic	0.94
RS1	O15537-1.2	I136T	Pathogenic	0.761
RS1	O15537-1.2	I136V	Neutral	0.01
RS1	O15537-1.2	I136W	Pathogenic	0.999
RS1	O15537-1.2	I136Y	Pathogenic	0.911
RS1	O15537-1.2	L137A	Pathogenic	0.565
RS1	O15537-1.2	L137C	Pathogenic	0.785
RS1	O15537-1.2	L137D	Pathogenic	0.966
RS1	O15537-1.2	L137E	Pathogenic	0.815
RS1	O15537-1.2	L137F	Pathogenic	0.566
RS1	O15537-1.2	L137G	Pathogenic	0.996
RS1	O15537-1.2	L137H	Pathogenic	0.946
RS1	O15537-1.2	L137I	Neutral	0.025
RS1	O15537-1.2	L137K	Neutral	0.244
RS1	O15537-1.2	L137M	Neutral	0.012
RS1	O15537-1.2	L137N	Pathogenic	0.852
RS1	O15537-1.2	L137P	Pathogenic	0.988
RS1	O15537-1.2	L137Q	Pathogenic	0.591
RS1	O15537-1.2	L137R	Neutral	0.276
RS1	O15537-1.2	L137S	Pathogenic	0.794
RS1	O15537-1.2	L137T	Neutral	0.441
RS1	O15537-1.2	L137V	Neutral	0.095
RS1	O15537-1.2	L137W	Pathogenic	0.971
RS1	O15537-1.2	L137Y	Pathogenic	0.718
RS1	O15537-1.2	T138A	Pathogenic	0.766
RS1	O15537-1.2	T138C	Pathogenic	0.807
RS1	O15537-1.2	T138D	Pathogenic	0.682
RS1	O15537-1.2	T138E	Pathogenic	0.775
RS1	O15537-1.2	T138F	Pathogenic	0.904
RS1	O15537-1.2	T138G	Pathogenic	0.992
RS1	O15537-1.2	T138H	Pathogenic	0.991
RS1	O15537-1.2	T138I	Pathogenic	0.545
RS1	O15537-1.2	T138K	Pathogenic	0.719
RS1	O15537-1.2	T138L	Pathogenic	0.595
RS1	O15537-1.2	T138M	Pathogenic	0.787
RS1	O15537-1.2	T138N	Neutral	0.321
RS1	O15537-1.2	T138P	Pathogenic	0.869
RS1	O15537-1.2	T138Q	Pathogenic	0.894
RS1	O15537-1.2	T138R	Pathogenic	0.752
RS1	O15537-1.2	T138S	Neutral	0.224
RS1	O15537-1.2	T138V	Neutral	0.307
RS1	O15537-1.2	T138W	Pathogenic	0.853
RS1	O15537-1.2	T138Y	Pathogenic	0.981
RS1	O15537-1.2	Q139A	Pathogenic	0.996
RS1	O15537-1.2	Q139C	Pathogenic	1.0
RS1	O15537-1.2	Q139D	Pathogenic	0.966
RS1	O15537-1.2	Q139E	Neutral	0.406
RS1	O15537-1.2	Q139F	Pathogenic	0.998
RS1	O15537-1.2	Q139G	Pathogenic	1.0
RS1	O15537-1.2	Q139H	Pathogenic	0.969
RS1	O15537-1.2	Q139I	Pathogenic	0.997
RS1	O15537-1.2	Q139K	Pathogenic	0.738
RS1	O15537-1.2	Q139L	Pathogenic	0.985
RS1	O15537-1.2	Q139M	Pathogenic	0.8
RS1	O15537-1.2	Q139N	Pathogenic	0.974
RS1	O15537-1.2	Q139P	Pathogenic	0.989
RS1	O15537-1.2	Q139R	Pathogenic	0.769
RS1	O15537-1.2	Q139S	Pathogenic	0.987
RS1	O15537-1.2	Q139T	Pathogenic	0.995
RS1	O15537-1.2	Q139V	Pathogenic	0.994
RS1	O15537-1.2	Q139W	Pathogenic	0.976
RS1	O15537-1.2	Q139Y	Pathogenic	0.983
RS1	O15537-1.2	G140A	Pathogenic	0.982
RS1	O15537-1.2	G140C	Pathogenic	1.0
RS1	O15537-1.2	G140D	Pathogenic	0.995
RS1	O15537-1.2	G140E	Pathogenic	1.0
RS1	O15537-1.2	G140F	Pathogenic	1.0
RS1	O15537-1.2	G140H	Pathogenic	1.0
RS1	O15537-1.2	G140I	Pathogenic	1.0
RS1	O15537-1.2	G140K	Pathogenic	0.999
RS1	O15537-1.2	G140L	Pathogenic	1.0
RS1	O15537-1.2	G140M	Pathogenic	1.0
RS1	O15537-1.2	G140N	Pathogenic	0.979
RS1	O15537-1.2	G140P	Pathogenic	0.999
RS1	O15537-1.2	G140Q	Pathogenic	1.0
RS1	O15537-1.2	G140R	Pathogenic	0.999
RS1	O15537-1.2	G140S	Pathogenic	0.99
RS1	O15537-1.2	G140T	Pathogenic	1.0
RS1	O15537-1.2	G140V	Pathogenic	1.0
RS1	O15537-1.2	G140W	Pathogenic	0.995
RS1	O15537-1.2	G140Y	Pathogenic	1.0
RS1	O15537-1.2	R141A	Pathogenic	0.996
RS1	O15537-1.2	R141C	Pathogenic	1.0
RS1	O15537-1.2	R141D	Pathogenic	1.0
RS1	O15537-1.2	R141E	Pathogenic	0.993
RS1	O15537-1.2	R141F	Pathogenic	0.995
RS1	O15537-1.2	R141G	Pathogenic	1.0
RS1	O15537-1.2	R141H	Pathogenic	0.964
RS1	O15537-1.2	R141I	Pathogenic	0.996
RS1	O15537-1.2	R141K	Pathogenic	0.822
RS1	O15537-1.2	R141L	Pathogenic	0.979
RS1	O15537-1.2	R141M	Pathogenic	0.948
RS1	O15537-1.2	R141N	Pathogenic	0.994
RS1	O15537-1.2	R141P	Pathogenic	0.998
RS1	O15537-1.2	R141Q	Pathogenic	0.9
RS1	O15537-1.2	R141S	Pathogenic	0.998
RS1	O15537-1.2	R141T	Pathogenic	0.995
RS1	O15537-1.2	R141V	Pathogenic	0.999
RS1	O15537-1.2	R141W	Pathogenic	0.989
RS1	O15537-1.2	R141Y	Pathogenic	0.994
RS1	O15537-1.2	C142A	Pathogenic	1.0
RS1	O15537-1.2	C142D	Pathogenic	1.0
RS1	O15537-1.2	C142E	Pathogenic	1.0
RS1	O15537-1.2	C142F	Pathogenic	1.0
RS1	O15537-1.2	C142G	Pathogenic	1.0
RS1	O15537-1.2	C142H	Pathogenic	1.0
RS1	O15537-1.2	C142I	Pathogenic	1.0
RS1	O15537-1.2	C142K	Pathogenic	1.0
RS1	O15537-1.2	C142L	Pathogenic	1.0
RS1	O15537-1.2	C142M	Pathogenic	1.0
RS1	O15537-1.2	C142N	Pathogenic	1.0
RS1	O15537-1.2	C142P	Pathogenic	1.0
RS1	O15537-1.2	C142Q	Pathogenic	1.0
RS1	O15537-1.2	C142R	Pathogenic	1.0
RS1	O15537-1.2	C142S	Pathogenic	1.0
RS1	O15537-1.2	C142T	Pathogenic	1.0
RS1	O15537-1.2	C142V	Pathogenic	1.0
RS1	O15537-1.2	C142W	Pathogenic	1.0
RS1	O15537-1.2	C142Y	Pathogenic	1.0
RS1	O15537-1.2	D143A	Pathogenic	0.997
RS1	O15537-1.2	D143C	Pathogenic	0.998
RS1	O15537-1.2	D143E	Pathogenic	0.576
RS1	O15537-1.2	D143F	Pathogenic	0.995
RS1	O15537-1.2	D143G	Pathogenic	0.993
RS1	O15537-1.2	D143H	Pathogenic	0.989
RS1	O15537-1.2	D143I	Pathogenic	0.994
RS1	O15537-1.2	D143K	Pathogenic	0.998
RS1	O15537-1.2	D143L	Pathogenic	0.999
RS1	O15537-1.2	D143M	Pathogenic	0.998
RS1	O15537-1.2	D143N	Pathogenic	0.869
RS1	O15537-1.2	D143P	Pathogenic	0.951
RS1	O15537-1.2	D143Q	Pathogenic	0.964
RS1	O15537-1.2	D143R	Pathogenic	1.0
RS1	O15537-1.2	D143S	Pathogenic	0.945
RS1	O15537-1.2	D143T	Pathogenic	0.98
RS1	O15537-1.2	D143V	Pathogenic	0.997
RS1	O15537-1.2	D143W	Pathogenic	0.999
RS1	O15537-1.2	D143Y	Pathogenic	0.999
RS1	O15537-1.2	I144A	Neutral	0.012
RS1	O15537-1.2	I144C	Neutral	0.034
RS1	O15537-1.2	I144D	Neutral	0.041
RS1	O15537-1.2	I144E	Neutral	0.041
RS1	O15537-1.2	I144F	Neutral	0.018
RS1	O15537-1.2	I144G	Pathogenic	0.708
RS1	O15537-1.2	I144H	Neutral	0.145
RS1	O15537-1.2	I144K	Neutral	0.02
RS1	O15537-1.2	I144L	Neutral	0.0
RS1	O15537-1.2	I144M	Neutral	0.001
RS1	O15537-1.2	I144N	Neutral	0.053
RS1	O15537-1.2	I144P	Neutral	0.451
RS1	O15537-1.2	I144Q	Neutral	0.083
RS1	O15537-1.2	I144R	Neutral	0.023
RS1	O15537-1.2	I144S	Neutral	0.036
RS1	O15537-1.2	I144T	Neutral	0.008
RS1	O15537-1.2	I144V	Neutral	0.0
RS1	O15537-1.2	I144W	Pathogenic	0.756
RS1	O15537-1.2	I144Y	Neutral	0.024
RS1	O15537-1.2	D145A	Pathogenic	0.996
RS1	O15537-1.2	D145C	Pathogenic	0.997
RS1	O15537-1.2	D145E	Neutral	0.472
RS1	O15537-1.2	D145F	Pathogenic	0.992
RS1	O15537-1.2	D145G	Pathogenic	0.99
RS1	O15537-1.2	D145H	Pathogenic	0.984
RS1	O15537-1.2	D145I	Pathogenic	0.99
RS1	O15537-1.2	D145K	Pathogenic	0.997
RS1	O15537-1.2	D145L	Pathogenic	0.999
RS1	O15537-1.2	D145M	Pathogenic	0.997
RS1	O15537-1.2	D145N	Pathogenic	0.815
RS1	O15537-1.2	D145P	Pathogenic	0.927
RS1	O15537-1.2	D145Q	Pathogenic	0.946
RS1	O15537-1.2	D145R	Pathogenic	1.0
RS1	O15537-1.2	D145S	Pathogenic	0.919
RS1	O15537-1.2	D145T	Pathogenic	0.97
RS1	O15537-1.2	D145V	Pathogenic	0.996
RS1	O15537-1.2	D145W	Pathogenic	0.998
RS1	O15537-1.2	D145Y	Pathogenic	0.999
RS1	O15537-1.2	E146A	Pathogenic	0.997
RS1	O15537-1.2	E146C	Pathogenic	1.0
RS1	O15537-1.2	E146D	Pathogenic	0.806
RS1	O15537-1.2	E146F	Pathogenic	0.998
RS1	O15537-1.2	E146G	Pathogenic	1.0
RS1	O15537-1.2	E146H	Pathogenic	0.977
RS1	O15537-1.2	E146I	Pathogenic	0.998
RS1	O15537-1.2	E146K	Pathogenic	0.951
RS1	O15537-1.2	E146L	Pathogenic	0.998
RS1	O15537-1.2	E146M	Pathogenic	0.996
RS1	O15537-1.2	E146N	Pathogenic	0.995
RS1	O15537-1.2	E146P	Pathogenic	0.99
RS1	O15537-1.2	E146Q	Pathogenic	0.66
RS1	O15537-1.2	E146R	Pathogenic	0.993
RS1	O15537-1.2	E146S	Pathogenic	0.989
RS1	O15537-1.2	E146T	Pathogenic	0.996
RS1	O15537-1.2	E146V	Pathogenic	0.995
RS1	O15537-1.2	E146W	Pathogenic	0.997
RS1	O15537-1.2	E146Y	Pathogenic	0.998
RS1	O15537-1.2	W147A	Pathogenic	1.0
RS1	O15537-1.2	W147C	Pathogenic	0.999
RS1	O15537-1.2	W147D	Pathogenic	0.999
RS1	O15537-1.2	W147E	Pathogenic	0.996
RS1	O15537-1.2	W147F	Pathogenic	0.925
RS1	O15537-1.2	W147G	Pathogenic	0.997
RS1	O15537-1.2	W147H	Pathogenic	0.994
RS1	O15537-1.2	W147I	Pathogenic	1.0
RS1	O15537-1.2	W147K	Pathogenic	0.989
RS1	O15537-1.2	W147L	Pathogenic	1.0
RS1	O15537-1.2	W147M	Pathogenic	0.995
RS1	O15537-1.2	W147N	Pathogenic	1.0
RS1	O15537-1.2	W147P	Pathogenic	1.0
RS1	O15537-1.2	W147Q	Pathogenic	0.989
RS1	O15537-1.2	W147R	Pathogenic	0.986
RS1	O15537-1.2	W147S	Pathogenic	0.999
RS1	O15537-1.2	W147T	Pathogenic	0.997
RS1	O15537-1.2	W147V	Pathogenic	1.0
RS1	O15537-1.2	W147Y	Neutral	0.256
RS1	O15537-1.2	M148A	Neutral	0.054
RS1	O15537-1.2	M148C	Neutral	0.14
RS1	O15537-1.2	M148D	Neutral	0.165
RS1	O15537-1.2	M148E	Neutral	0.029
RS1	O15537-1.2	M148F	Neutral	0.009
RS1	O15537-1.2	M148G	Pathogenic	0.634
RS1	O15537-1.2	M148H	Neutral	0.107
RS1	O15537-1.2	M148I	Neutral	0.001
RS1	O15537-1.2	M148K	Neutral	0.002
RS1	O15537-1.2	M148L	Neutral	0.0
RS1	O15537-1.2	M148N	Neutral	0.038
RS1	O15537-1.2	M148P	Neutral	0.369
RS1	O15537-1.2	M148Q	Neutral	0.002
RS1	O15537-1.2	M148R	Neutral	0.003
RS1	O15537-1.2	M148S	Neutral	0.026
RS1	O15537-1.2	M148T	Neutral	0.034
RS1	O15537-1.2	M148V	Neutral	0.005
RS1	O15537-1.2	M148W	Neutral	0.035
RS1	O15537-1.2	M148Y	Neutral	0.101
RS1	O15537-1.2	T149A	Pathogenic	0.992
RS1	O15537-1.2	T149C	Pathogenic	0.994
RS1	O15537-1.2	T149D	Pathogenic	0.988
RS1	O15537-1.2	T149E	Pathogenic	0.993
RS1	O15537-1.2	T149F	Pathogenic	0.997
RS1	O15537-1.2	T149G	Pathogenic	1.0
RS1	O15537-1.2	T149H	Pathogenic	1.0
RS1	O15537-1.2	T149I	Pathogenic	0.979
RS1	O15537-1.2	T149K	Pathogenic	0.99
RS1	O15537-1.2	T149L	Pathogenic	0.983
RS1	O15537-1.2	T149M	Pathogenic	0.993
RS1	O15537-1.2	T149N	Pathogenic	0.948
RS1	O15537-1.2	T149P	Pathogenic	0.996
RS1	O15537-1.2	T149Q	Pathogenic	0.997
RS1	O15537-1.2	T149R	Pathogenic	0.992
RS1	O15537-1.2	T149S	Pathogenic	0.918
RS1	O15537-1.2	T149V	Pathogenic	0.945
RS1	O15537-1.2	T149W	Pathogenic	0.996
RS1	O15537-1.2	T149Y	Pathogenic	1.0
RS1	O15537-1.2	K150A	Pathogenic	0.992
RS1	O15537-1.2	K150C	Pathogenic	0.999
RS1	O15537-1.2	K150D	Pathogenic	0.999
RS1	O15537-1.2	K150E	Pathogenic	0.911
RS1	O15537-1.2	K150F	Pathogenic	0.99
RS1	O15537-1.2	K150G	Pathogenic	0.999
RS1	O15537-1.2	K150H	Pathogenic	0.988
RS1	O15537-1.2	K150I	Pathogenic	0.991
RS1	O15537-1.2	K150L	Pathogenic	0.956
RS1	O15537-1.2	K150M	Pathogenic	0.895
RS1	O15537-1.2	K150N	Pathogenic	0.987
RS1	O15537-1.2	K150P	Pathogenic	0.975
RS1	O15537-1.2	K150Q	Pathogenic	0.807
RS1	O15537-1.2	K150R	Pathogenic	0.718
RS1	O15537-1.2	K150S	Pathogenic	0.972
RS1	O15537-1.2	K150T	Pathogenic	0.989
RS1	O15537-1.2	K150V	Pathogenic	0.987
RS1	O15537-1.2	K150W	Pathogenic	0.984
RS1	O15537-1.2	K150Y	Pathogenic	0.989
RS1	O15537-1.2	Y151A	Pathogenic	1.0
RS1	O15537-1.2	Y151C	Pathogenic	1.0
RS1	O15537-1.2	Y151D	Pathogenic	1.0
RS1	O15537-1.2	Y151E	Pathogenic	0.998
RS1	O15537-1.2	Y151F	Neutral	0.128
RS1	O15537-1.2	Y151G	Pathogenic	1.0
RS1	O15537-1.2	Y151H	Pathogenic	0.549
RS1	O15537-1.2	Y151I	Pathogenic	0.997
RS1	O15537-1.2	Y151K	Pathogenic	0.994
RS1	O15537-1.2	Y151L	Pathogenic	0.997
RS1	O15537-1.2	Y151M	Pathogenic	0.999
RS1	O15537-1.2	Y151N	Pathogenic	0.999
RS1	O15537-1.2	Y151P	Pathogenic	1.0
RS1	O15537-1.2	Y151Q	Pathogenic	0.994
RS1	O15537-1.2	Y151R	Pathogenic	0.994
RS1	O15537-1.2	Y151S	Pathogenic	1.0
RS1	O15537-1.2	Y151T	Pathogenic	1.0
RS1	O15537-1.2	Y151V	Pathogenic	0.999
RS1	O15537-1.2	Y151W	Neutral	0.326
RS1	O15537-1.2	S152A	Pathogenic	0.981
RS1	O15537-1.2	S152C	Pathogenic	0.998
RS1	O15537-1.2	S152D	Pathogenic	0.995
RS1	O15537-1.2	S152E	Pathogenic	0.997
RS1	O15537-1.2	S152F	Pathogenic	0.999
RS1	O15537-1.2	S152G	Pathogenic	0.999
RS1	O15537-1.2	S152H	Pathogenic	1.0
RS1	O15537-1.2	S152I	Pathogenic	0.999
RS1	O15537-1.2	S152K	Pathogenic	0.996
RS1	O15537-1.2	S152L	Pathogenic	0.999
RS1	O15537-1.2	S152M	Pathogenic	0.999
RS1	O15537-1.2	S152N	Pathogenic	0.978
RS1	O15537-1.2	S152P	Pathogenic	0.999
RS1	O15537-1.2	S152Q	Pathogenic	0.999
RS1	O15537-1.2	S152R	Pathogenic	0.999
RS1	O15537-1.2	S152T	Pathogenic	0.986
RS1	O15537-1.2	S152V	Pathogenic	1.0
RS1	O15537-1.2	S152W	Pathogenic	1.0
RS1	O15537-1.2	S152Y	Pathogenic	1.0
RS1	O15537-1.2	V153A	Neutral	0.014
RS1	O15537-1.2	V153C	Neutral	0.202
RS1	O15537-1.2	V153D	Neutral	0.236
RS1	O15537-1.2	V153E	Neutral	0.051
RS1	O15537-1.2	V153F	Neutral	0.134
RS1	O15537-1.2	V153G	Pathogenic	0.73
RS1	O15537-1.2	V153H	Pathogenic	0.643
RS1	O15537-1.2	V153I	Neutral	0.0
RS1	O15537-1.2	V153K	Neutral	0.038
RS1	O15537-1.2	V153L	Neutral	0.004
RS1	O15537-1.2	V153M	Neutral	0.009
RS1	O15537-1.2	V153N	Neutral	0.285
RS1	O15537-1.2	V153P	Neutral	0.477
RS1	O15537-1.2	V153Q	Neutral	0.116
RS1	O15537-1.2	V153R	Neutral	0.232
RS1	O15537-1.2	V153S	Neutral	0.211
RS1	O15537-1.2	V153T	Neutral	0.008
RS1	O15537-1.2	V153W	Pathogenic	0.798
RS1	O15537-1.2	V153Y	Neutral	0.239
RS1	O15537-1.2	Q154A	Pathogenic	0.998
RS1	O15537-1.2	Q154C	Pathogenic	1.0
RS1	O15537-1.2	Q154D	Pathogenic	0.981
RS1	O15537-1.2	Q154E	Pathogenic	0.555
RS1	O15537-1.2	Q154F	Pathogenic	0.999
RS1	O15537-1.2	Q154G	Pathogenic	1.0
RS1	O15537-1.2	Q154H	Pathogenic	0.983
RS1	O15537-1.2	Q154I	Pathogenic	0.998
RS1	O15537-1.2	Q154K	Pathogenic	0.837
RS1	O15537-1.2	Q154L	Pathogenic	0.992
RS1	O15537-1.2	Q154M	Pathogenic	0.879
RS1	O15537-1.2	Q154N	Pathogenic	0.985
RS1	O15537-1.2	Q154P	Pathogenic	0.994
RS1	O15537-1.2	Q154R	Pathogenic	0.858
RS1	O15537-1.2	Q154S	Pathogenic	0.993
RS1	O15537-1.2	Q154T	Pathogenic	0.997
RS1	O15537-1.2	Q154V	Pathogenic	0.997
RS1	O15537-1.2	Q154W	Pathogenic	0.987
RS1	O15537-1.2	Q154Y	Pathogenic	0.99
RS1	O15537-1.2	Y155A	Pathogenic	1.0
RS1	O15537-1.2	Y155C	Pathogenic	1.0
RS1	O15537-1.2	Y155D	Pathogenic	1.0
RS1	O15537-1.2	Y155E	Pathogenic	0.997
RS1	O15537-1.2	Y155F	Neutral	0.085
RS1	O15537-1.2	Y155G	Pathogenic	1.0
RS1	O15537-1.2	Y155H	Neutral	0.437
RS1	O15537-1.2	Y155I	Pathogenic	0.995
RS1	O15537-1.2	Y155K	Pathogenic	0.991
RS1	O15537-1.2	Y155L	Pathogenic	0.996
RS1	O15537-1.2	Y155M	Pathogenic	0.998
RS1	O15537-1.2	Y155N	Pathogenic	0.998
RS1	O15537-1.2	Y155P	Pathogenic	1.0
RS1	O15537-1.2	Y155Q	Pathogenic	0.991
RS1	O15537-1.2	Y155R	Pathogenic	0.991
RS1	O15537-1.2	Y155S	Pathogenic	0.999
RS1	O15537-1.2	Y155T	Pathogenic	1.0
RS1	O15537-1.2	Y155V	Pathogenic	0.999
RS1	O15537-1.2	Y155W	Neutral	0.235
RS1	O15537-1.2	R156A	Pathogenic	0.992
RS1	O15537-1.2	R156C	Pathogenic	0.999
RS1	O15537-1.2	R156D	Pathogenic	1.0
RS1	O15537-1.2	R156E	Pathogenic	0.985
RS1	O15537-1.2	R156F	Pathogenic	0.99
RS1	O15537-1.2	R156G	Pathogenic	0.999
RS1	O15537-1.2	R156H	Pathogenic	0.928
RS1	O15537-1.2	R156I	Pathogenic	0.991
RS1	O15537-1.2	R156K	Pathogenic	0.686
RS1	O15537-1.2	R156L	Pathogenic	0.957
RS1	O15537-1.2	R156M	Pathogenic	0.897
RS1	O15537-1.2	R156N	Pathogenic	0.987
RS1	O15537-1.2	R156P	Pathogenic	0.996
RS1	O15537-1.2	R156Q	Pathogenic	0.81
RS1	O15537-1.2	R156S	Pathogenic	0.996
RS1	O15537-1.2	R156T	Pathogenic	0.99
RS1	O15537-1.2	R156V	Pathogenic	0.998
RS1	O15537-1.2	R156W	Pathogenic	0.977
RS1	O15537-1.2	R156Y	Pathogenic	0.987
RS1	O15537-1.2	T157A	Neutral	0.389
RS1	O15537-1.2	T157C	Neutral	0.449
RS1	O15537-1.2	T157D	Neutral	0.294
RS1	O15537-1.2	T157E	Neutral	0.401
RS1	O15537-1.2	T157F	Pathogenic	0.646
RS1	O15537-1.2	T157G	Pathogenic	0.959
RS1	O15537-1.2	T157H	Pathogenic	0.957
RS1	O15537-1.2	T157I	Neutral	0.189
RS1	O15537-1.2	T157K	Neutral	0.332
RS1	O15537-1.2	T157L	Neutral	0.222
RS1	O15537-1.2	T157M	Neutral	0.418
RS1	O15537-1.2	T157N	Neutral	0.084
RS1	O15537-1.2	T157P	Pathogenic	0.563
RS1	O15537-1.2	T157Q	Pathogenic	0.622
RS1	O15537-1.2	T157R	Neutral	0.37
RS1	O15537-1.2	T157S	Neutral	0.053
RS1	O15537-1.2	T157V	Neutral	0.079
RS1	O15537-1.2	T157W	Pathogenic	0.529
RS1	O15537-1.2	T157Y	Pathogenic	0.911
RS1	O15537-1.2	D158A	Neutral	0.206
RS1	O15537-1.2	D158C	Neutral	0.248
RS1	O15537-1.2	D158E	Neutral	0.001
RS1	O15537-1.2	D158F	Neutral	0.109
RS1	O15537-1.2	D158G	Neutral	0.09
RS1	O15537-1.2	D158H	Neutral	0.056
RS1	O15537-1.2	D158I	Neutral	0.091
RS1	O15537-1.2	D158K	Neutral	0.228
RS1	O15537-1.2	D158L	Neutral	0.442
RS1	O15537-1.2	D158M	Neutral	0.237
RS1	O15537-1.2	D158N	Neutral	0.004
RS1	O15537-1.2	D158P	Neutral	0.012
RS1	O15537-1.2	D158Q	Neutral	0.017
RS1	O15537-1.2	D158R	Pathogenic	0.692
RS1	O15537-1.2	D158S	Neutral	0.011
RS1	O15537-1.2	D158T	Neutral	0.031
RS1	O15537-1.2	D158V	Neutral	0.193
RS1	O15537-1.2	D158W	Neutral	0.327
RS1	O15537-1.2	D158Y	Neutral	0.406
RS1	O15537-1.2	E159A	Pathogenic	0.989
RS1	O15537-1.2	E159C	Pathogenic	1.0
RS1	O15537-1.2	E159D	Pathogenic	0.541
RS1	O15537-1.2	E159F	Pathogenic	0.994
RS1	O15537-1.2	E159G	Pathogenic	0.999
RS1	O15537-1.2	E159H	Pathogenic	0.924
RS1	O15537-1.2	E159I	Pathogenic	0.992
RS1	O15537-1.2	E159K	Pathogenic	0.847
RS1	O15537-1.2	E159L	Pathogenic	0.994
RS1	O15537-1.2	E159M	Pathogenic	0.984
RS1	O15537-1.2	E159N	Pathogenic	0.982
RS1	O15537-1.2	E159P	Pathogenic	0.966
RS1	O15537-1.2	E159Q	Neutral	0.355
RS1	O15537-1.2	E159R	Pathogenic	0.977
RS1	O15537-1.2	E159S	Pathogenic	0.962
RS1	O15537-1.2	E159T	Pathogenic	0.985
RS1	O15537-1.2	E159V	Pathogenic	0.982
RS1	O15537-1.2	E159W	Pathogenic	0.99
RS1	O15537-1.2	E159Y	Pathogenic	0.993
RS1	O15537-1.2	R160A	Neutral	0.0
RS1	O15537-1.2	R160C	Neutral	0.002
RS1	O15537-1.2	R160D	Neutral	0.01
RS1	O15537-1.2	R160E	Neutral	0.0
RS1	O15537-1.2	R160F	Neutral	0.0
RS1	O15537-1.2	R160G	Neutral	0.004
RS1	O15537-1.2	R160H	Neutral	0.0
RS1	O15537-1.2	R160I	Neutral	0.0
RS1	O15537-1.2	R160K	Neutral	0.0
RS1	O15537-1.2	R160L	Neutral	0.0
RS1	O15537-1.2	R160M	Neutral	0.0
RS1	O15537-1.2	R160N	Neutral	0.0
RS1	O15537-1.2	R160P	Neutral	0.001
RS1	O15537-1.2	R160Q	Neutral	0.0
RS1	O15537-1.2	R160S	Neutral	0.0
RS1	O15537-1.2	R160T	Neutral	0.0
RS1	O15537-1.2	R160V	Neutral	0.001
RS1	O15537-1.2	R160W	Neutral	0.0
RS1	O15537-1.2	R160Y	Neutral	0.0
RS1	O15537-1.2	L161A	Pathogenic	0.997
RS1	O15537-1.2	L161C	Pathogenic	0.999
RS1	O15537-1.2	L161D	Pathogenic	1.0
RS1	O15537-1.2	L161E	Pathogenic	0.999
RS1	O15537-1.2	L161F	Pathogenic	0.997
RS1	O15537-1.2	L161G	Pathogenic	1.0
RS1	O15537-1.2	L161H	Pathogenic	1.0
RS1	O15537-1.2	L161I	Pathogenic	0.879
RS1	O15537-1.2	L161K	Pathogenic	0.989
RS1	O15537-1.2	L161M	Pathogenic	0.779
RS1	O15537-1.2	L161N	Pathogenic	0.999
RS1	O15537-1.2	L161P	Pathogenic	1.0
RS1	O15537-1.2	L161Q	Pathogenic	0.998
RS1	O15537-1.2	L161R	Pathogenic	0.991
RS1	O15537-1.2	L161S	Pathogenic	0.999
RS1	O15537-1.2	L161T	Pathogenic	0.995
RS1	O15537-1.2	L161V	Pathogenic	0.967
RS1	O15537-1.2	L161W	Pathogenic	1.0
RS1	O15537-1.2	L161Y	Pathogenic	0.999
RS1	O15537-1.2	N162A	Pathogenic	1.0
RS1	O15537-1.2	N162C	Pathogenic	1.0
RS1	O15537-1.2	N162D	Pathogenic	0.962
RS1	O15537-1.2	N162E	Pathogenic	0.996
RS1	O15537-1.2	N162F	Pathogenic	0.999
RS1	O15537-1.2	N162G	Pathogenic	0.992
RS1	O15537-1.2	N162H	Pathogenic	0.914
RS1	O15537-1.2	N162I	Pathogenic	0.999
RS1	O15537-1.2	N162K	Pathogenic	0.994
RS1	O15537-1.2	N162L	Pathogenic	0.999
RS1	O15537-1.2	N162M	Pathogenic	0.997
RS1	O15537-1.2	N162P	Pathogenic	0.999
RS1	O15537-1.2	N162Q	Pathogenic	0.992
RS1	O15537-1.2	N162R	Pathogenic	0.995
RS1	O15537-1.2	N162S	Pathogenic	0.938
RS1	O15537-1.2	N162T	Pathogenic	0.976
RS1	O15537-1.2	N162V	Pathogenic	0.999
RS1	O15537-1.2	N162W	Pathogenic	1.0
RS1	O15537-1.2	N162Y	Pathogenic	0.999
RS1	O15537-1.2	W163A	Pathogenic	1.0
RS1	O15537-1.2	W163C	Pathogenic	0.999
RS1	O15537-1.2	W163D	Pathogenic	1.0
RS1	O15537-1.2	W163E	Pathogenic	0.997
RS1	O15537-1.2	W163F	Pathogenic	0.942
RS1	O15537-1.2	W163G	Pathogenic	0.998
RS1	O15537-1.2	W163H	Pathogenic	0.995
RS1	O15537-1.2	W163I	Pathogenic	1.0
RS1	O15537-1.2	W163K	Pathogenic	0.992
RS1	O15537-1.2	W163L	Pathogenic	1.0
RS1	O15537-1.2	W163M	Pathogenic	0.996
RS1	O15537-1.2	W163N	Pathogenic	1.0
RS1	O15537-1.2	W163P	Pathogenic	1.0
RS1	O15537-1.2	W163Q	Pathogenic	0.991
RS1	O15537-1.2	W163R	Pathogenic	0.989
RS1	O15537-1.2	W163S	Pathogenic	0.999
RS1	O15537-1.2	W163T	Pathogenic	0.997
RS1	O15537-1.2	W163V	Pathogenic	1.0
RS1	O15537-1.2	W163Y	Neutral	0.31
RS1	O15537-1.2	I164A	Neutral	0.279
RS1	O15537-1.2	I164C	Pathogenic	0.522
RS1	O15537-1.2	I164D	Pathogenic	0.571
RS1	O15537-1.2	I164E	Pathogenic	0.567
RS1	O15537-1.2	I164F	Neutral	0.355
RS1	O15537-1.2	I164G	Pathogenic	0.987
RS1	O15537-1.2	I164H	Pathogenic	0.839
RS1	O15537-1.2	I164K	Neutral	0.382
RS1	O15537-1.2	I164L	Neutral	0.009
RS1	O15537-1.2	I164M	Neutral	0.024
RS1	O15537-1.2	I164N	Pathogenic	0.632
RS1	O15537-1.2	I164P	Pathogenic	0.962
RS1	O15537-1.2	I164Q	Pathogenic	0.734
RS1	O15537-1.2	I164R	Neutral	0.422
RS1	O15537-1.2	I164S	Pathogenic	0.535
RS1	O15537-1.2	I164T	Neutral	0.19
RS1	O15537-1.2	I164V	Neutral	0.001
RS1	O15537-1.2	I164W	Pathogenic	0.99
RS1	O15537-1.2	I164Y	Neutral	0.432
RS1	O15537-1.2	Y165A	Pathogenic	1.0
RS1	O15537-1.2	Y165C	Pathogenic	1.0
RS1	O15537-1.2	Y165D	Pathogenic	1.0
RS1	O15537-1.2	Y165E	Pathogenic	0.998
RS1	O15537-1.2	Y165F	Neutral	0.108
RS1	O15537-1.2	Y165G	Pathogenic	1.0
RS1	O15537-1.2	Y165H	Pathogenic	0.501
RS1	O15537-1.2	Y165I	Pathogenic	0.996
RS1	O15537-1.2	Y165K	Pathogenic	0.993
RS1	O15537-1.2	Y165L	Pathogenic	0.997
RS1	O15537-1.2	Y165M	Pathogenic	0.999
RS1	O15537-1.2	Y165N	Pathogenic	0.998
RS1	O15537-1.2	Y165P	Pathogenic	1.0
RS1	O15537-1.2	Y165Q	Pathogenic	0.993
RS1	O15537-1.2	Y165R	Pathogenic	0.993
RS1	O15537-1.2	Y165S	Pathogenic	1.0
RS1	O15537-1.2	Y165T	Pathogenic	1.0
RS1	O15537-1.2	Y165V	Pathogenic	0.999
RS1	O15537-1.2	Y165W	Neutral	0.285
RS1	O15537-1.2	Y166A	Pathogenic	1.0
RS1	O15537-1.2	Y166C	Pathogenic	1.0
RS1	O15537-1.2	Y166D	Pathogenic	1.0
RS1	O15537-1.2	Y166E	Pathogenic	0.999
RS1	O15537-1.2	Y166F	Neutral	0.288
RS1	O15537-1.2	Y166G	Pathogenic	1.0
RS1	O15537-1.2	Y166H	Pathogenic	0.771
RS1	O15537-1.2	Y166I	Pathogenic	0.999
RS1	O15537-1.2	Y166K	Pathogenic	0.998
RS1	O15537-1.2	Y166L	Pathogenic	0.999
RS1	O15537-1.2	Y166M	Pathogenic	1.0
RS1	O15537-1.2	Y166N	Pathogenic	0.999
RS1	O15537-1.2	Y166P	Pathogenic	1.0
RS1	O15537-1.2	Y166Q	Pathogenic	0.998
RS1	O15537-1.2	Y166R	Pathogenic	0.998
RS1	O15537-1.2	Y166S	Pathogenic	1.0
RS1	O15537-1.2	Y166T	Pathogenic	1.0
RS1	O15537-1.2	Y166V	Pathogenic	1.0
RS1	O15537-1.2	Y166W	Pathogenic	0.572
RS1	O15537-1.2	K167A	Pathogenic	0.999
RS1	O15537-1.2	K167C	Pathogenic	1.0
RS1	O15537-1.2	K167D	Pathogenic	1.0
RS1	O15537-1.2	K167E	Pathogenic	0.984
RS1	O15537-1.2	K167F	Pathogenic	0.998
RS1	O15537-1.2	K167G	Pathogenic	1.0
RS1	O15537-1.2	K167H	Pathogenic	0.998
RS1	O15537-1.2	K167I	Pathogenic	0.999
RS1	O15537-1.2	K167L	Pathogenic	0.992
RS1	O15537-1.2	K167M	Pathogenic	0.981
RS1	O15537-1.2	K167N	Pathogenic	0.998
RS1	O15537-1.2	K167P	Pathogenic	0.996
RS1	O15537-1.2	K167Q	Pathogenic	0.961
RS1	O15537-1.2	K167R	Pathogenic	0.938
RS1	O15537-1.2	K167S	Pathogenic	0.995
RS1	O15537-1.2	K167T	Pathogenic	0.998
RS1	O15537-1.2	K167V	Pathogenic	0.998
RS1	O15537-1.2	K167W	Pathogenic	0.997
RS1	O15537-1.2	K167Y	Pathogenic	0.998
RS1	O15537-1.2	D168A	Pathogenic	0.999
RS1	O15537-1.2	D168C	Pathogenic	0.999
RS1	O15537-1.2	D168E	Pathogenic	0.83
RS1	O15537-1.2	D168F	Pathogenic	0.999
RS1	O15537-1.2	D168G	Pathogenic	0.998
RS1	O15537-1.2	D168H	Pathogenic	0.997
RS1	O15537-1.2	D168I	Pathogenic	0.998
RS1	O15537-1.2	D168K	Pathogenic	0.999
RS1	O15537-1.2	D168L	Pathogenic	1.0
RS1	O15537-1.2	D168M	Pathogenic	0.999
RS1	O15537-1.2	D168N	Pathogenic	0.96
RS1	O15537-1.2	D168P	Pathogenic	0.986
RS1	O15537-1.2	D168Q	Pathogenic	0.99
RS1	O15537-1.2	D168R	Pathogenic	1.0
RS1	O15537-1.2	D168S	Pathogenic	0.984
RS1	O15537-1.2	D168T	Pathogenic	0.994
RS1	O15537-1.2	D168V	Pathogenic	0.999
RS1	O15537-1.2	D168W	Pathogenic	1.0
RS1	O15537-1.2	D168Y	Pathogenic	1.0
RS1	O15537-1.2	Q169A	Pathogenic	0.999
RS1	O15537-1.2	Q169C	Pathogenic	1.0
RS1	O15537-1.2	Q169D	Pathogenic	0.987
RS1	O15537-1.2	Q169E	Pathogenic	0.653
RS1	O15537-1.2	Q169F	Pathogenic	0.999
RS1	O15537-1.2	Q169G	Pathogenic	1.0
RS1	O15537-1.2	Q169H	Pathogenic	0.989
RS1	O15537-1.2	Q169I	Pathogenic	0.999
RS1	O15537-1.2	Q169K	Pathogenic	0.885
RS1	O15537-1.2	Q169L	Pathogenic	0.994
RS1	O15537-1.2	Q169M	Pathogenic	0.917
RS1	O15537-1.2	Q169N	Pathogenic	0.99
RS1	O15537-1.2	Q169P	Pathogenic	0.996
RS1	O15537-1.2	Q169R	Pathogenic	0.901
RS1	O15537-1.2	Q169S	Pathogenic	0.995
RS1	O15537-1.2	Q169T	Pathogenic	0.998
RS1	O15537-1.2	Q169V	Pathogenic	0.998
RS1	O15537-1.2	Q169W	Pathogenic	0.991
RS1	O15537-1.2	Q169Y	Pathogenic	0.994
RS1	O15537-1.2	T170A	Pathogenic	0.996
RS1	O15537-1.2	T170C	Pathogenic	0.997
RS1	O15537-1.2	T170D	Pathogenic	0.993
RS1	O15537-1.2	T170E	Pathogenic	0.996
RS1	O15537-1.2	T170F	Pathogenic	0.998
RS1	O15537-1.2	T170G	Pathogenic	1.0
RS1	O15537-1.2	T170H	Pathogenic	1.0
RS1	O15537-1.2	T170I	Pathogenic	0.988
RS1	O15537-1.2	T170K	Pathogenic	0.994
RS1	O15537-1.2	T170L	Pathogenic	0.99
RS1	O15537-1.2	T170M	Pathogenic	0.996
RS1	O15537-1.2	T170N	Pathogenic	0.97
RS1	O15537-1.2	T170P	Pathogenic	0.998
RS1	O15537-1.2	T170Q	Pathogenic	0.998
RS1	O15537-1.2	T170R	Pathogenic	0.995
RS1	O15537-1.2	T170S	Pathogenic	0.952
RS1	O15537-1.2	T170V	Pathogenic	0.968
RS1	O15537-1.2	T170W	Pathogenic	0.998
RS1	O15537-1.2	T170Y	Pathogenic	1.0
RS1	O15537-1.2	G171A	Pathogenic	0.998
RS1	O15537-1.2	G171C	Pathogenic	1.0
RS1	O15537-1.2	G171D	Pathogenic	0.999
RS1	O15537-1.2	G171E	Pathogenic	1.0
RS1	O15537-1.2	G171F	Pathogenic	1.0
RS1	O15537-1.2	G171H	Pathogenic	1.0
RS1	O15537-1.2	G171I	Pathogenic	1.0
RS1	O15537-1.2	G171K	Pathogenic	1.0
RS1	O15537-1.2	G171L	Pathogenic	1.0
RS1	O15537-1.2	G171M	Pathogenic	1.0
RS1	O15537-1.2	G171N	Pathogenic	0.998
RS1	O15537-1.2	G171P	Pathogenic	1.0
RS1	O15537-1.2	G171Q	Pathogenic	1.0
RS1	O15537-1.2	G171R	Pathogenic	1.0
RS1	O15537-1.2	G171S	Pathogenic	0.999
RS1	O15537-1.2	G171T	Pathogenic	1.0
RS1	O15537-1.2	G171V	Pathogenic	1.0
RS1	O15537-1.2	G171W	Pathogenic	1.0
RS1	O15537-1.2	G171Y	Pathogenic	1.0
RS1	O15537-1.2	N172A	Pathogenic	1.0
RS1	O15537-1.2	N172C	Pathogenic	1.0
RS1	O15537-1.2	N172D	Pathogenic	0.985
RS1	O15537-1.2	N172E	Pathogenic	0.998
RS1	O15537-1.2	N172F	Pathogenic	1.0
RS1	O15537-1.2	N172G	Pathogenic	0.997
RS1	O15537-1.2	N172H	Pathogenic	0.965
RS1	O15537-1.2	N172I	Pathogenic	0.999
RS1	O15537-1.2	N172K	Pathogenic	0.998
RS1	O15537-1.2	N172L	Pathogenic	1.0
RS1	O15537-1.2	N172M	Pathogenic	0.999
RS1	O15537-1.2	N172P	Pathogenic	0.999
RS1	O15537-1.2	N172Q	Pathogenic	0.997
RS1	O15537-1.2	N172R	Pathogenic	0.998
RS1	O15537-1.2	N172S	Pathogenic	0.975
RS1	O15537-1.2	N172T	Pathogenic	0.991
RS1	O15537-1.2	N172V	Pathogenic	1.0
RS1	O15537-1.2	N172W	Pathogenic	1.0
RS1	O15537-1.2	N172Y	Pathogenic	1.0
RS1	O15537-1.2	N173A	Pathogenic	1.0
RS1	O15537-1.2	N173C	Pathogenic	1.0
RS1	O15537-1.2	N173D	Pathogenic	0.985
RS1	O15537-1.2	N173E	Pathogenic	0.998
RS1	O15537-1.2	N173F	Pathogenic	1.0
RS1	O15537-1.2	N173G	Pathogenic	0.997
RS1	O15537-1.2	N173H	Pathogenic	0.965
RS1	O15537-1.2	N173I	Pathogenic	0.999
RS1	O15537-1.2	N173K	Pathogenic	0.998
RS1	O15537-1.2	N173L	Pathogenic	1.0
RS1	O15537-1.2	N173M	Pathogenic	0.999
RS1	O15537-1.2	N173P	Pathogenic	0.999
RS1	O15537-1.2	N173Q	Pathogenic	0.997
RS1	O15537-1.2	N173R	Pathogenic	0.998
RS1	O15537-1.2	N173S	Pathogenic	0.975
RS1	O15537-1.2	N173T	Pathogenic	0.991
RS1	O15537-1.2	N173V	Pathogenic	1.0
RS1	O15537-1.2	N173W	Pathogenic	1.0
RS1	O15537-1.2	N173Y	Pathogenic	1.0
RS1	O15537-1.2	R174A	Pathogenic	0.997
RS1	O15537-1.2	R174C	Pathogenic	1.0
RS1	O15537-1.2	R174D	Pathogenic	1.0
RS1	O15537-1.2	R174E	Pathogenic	0.995
RS1	O15537-1.2	R174F	Pathogenic	0.996
RS1	O15537-1.2	R174G	Pathogenic	1.0
RS1	O15537-1.2	R174H	Pathogenic	0.973
RS1	O15537-1.2	R174I	Pathogenic	0.997
RS1	O15537-1.2	R174K	Pathogenic	0.858
RS1	O15537-1.2	R174L	Pathogenic	0.984
RS1	O15537-1.2	R174M	Pathogenic	0.96
RS1	O15537-1.2	R174N	Pathogenic	0.995
RS1	O15537-1.2	R174P	Pathogenic	0.999
RS1	O15537-1.2	R174Q	Pathogenic	0.921
RS1	O15537-1.2	R174S	Pathogenic	0.998
RS1	O15537-1.2	R174T	Pathogenic	0.996
RS1	O15537-1.2	R174V	Pathogenic	0.999
RS1	O15537-1.2	R174W	Pathogenic	0.991
RS1	O15537-1.2	R174Y	Pathogenic	0.995
RS1	O15537-1.2	V175A	Pathogenic	0.82
RS1	O15537-1.2	V175C	Pathogenic	0.988
RS1	O15537-1.2	V175D	Pathogenic	0.99
RS1	O15537-1.2	V175E	Pathogenic	0.946
RS1	O15537-1.2	V175F	Pathogenic	0.981
RS1	O15537-1.2	V175G	Pathogenic	0.999
RS1	O15537-1.2	V175H	Pathogenic	0.998
RS1	O15537-1.2	V175I	Neutral	0.024
RS1	O15537-1.2	V175K	Pathogenic	0.929
RS1	O15537-1.2	V175L	Pathogenic	0.551
RS1	O15537-1.2	V175M	Pathogenic	0.755
RS1	O15537-1.2	V175N	Pathogenic	0.992
RS1	O15537-1.2	V175P	Pathogenic	0.997
RS1	O15537-1.2	V175Q	Pathogenic	0.977
RS1	O15537-1.2	V175R	Pathogenic	0.99
RS1	O15537-1.2	V175S	Pathogenic	0.989
RS1	O15537-1.2	V175T	Pathogenic	0.735
RS1	O15537-1.2	V175W	Pathogenic	0.999
RS1	O15537-1.2	V175Y	Pathogenic	0.99
RS1	O15537-1.2	F176A	Pathogenic	0.997
RS1	O15537-1.2	F176C	Pathogenic	0.999
RS1	O15537-1.2	F176D	Pathogenic	0.995
RS1	O15537-1.2	F176E	Pathogenic	0.995
RS1	O15537-1.2	F176G	Pathogenic	0.999
RS1	O15537-1.2	F176H	Pathogenic	0.947
RS1	O15537-1.2	F176I	Pathogenic	0.985
RS1	O15537-1.2	F176K	Pathogenic	0.984
RS1	O15537-1.2	F176L	Pathogenic	0.982
RS1	O15537-1.2	F176M	Pathogenic	0.957
RS1	O15537-1.2	F176N	Pathogenic	0.996
RS1	O15537-1.2	F176P	Pathogenic	1.0
RS1	O15537-1.2	F176Q	Pathogenic	0.997
RS1	O15537-1.2	F176R	Pathogenic	0.987
RS1	O15537-1.2	F176S	Pathogenic	0.994
RS1	O15537-1.2	F176T	Pathogenic	0.995
RS1	O15537-1.2	F176V	Pathogenic	0.995
RS1	O15537-1.2	F176W	Pathogenic	0.844
RS1	O15537-1.2	F176Y	Neutral	0.043
RS1	O15537-1.2	Y177A	Pathogenic	1.0
RS1	O15537-1.2	Y177C	Pathogenic	1.0
RS1	O15537-1.2	Y177D	Pathogenic	0.999
RS1	O15537-1.2	Y177E	Pathogenic	0.995
RS1	O15537-1.2	Y177F	Neutral	0.055
RS1	O15537-1.2	Y177G	Pathogenic	1.0
RS1	O15537-1.2	Y177H	Neutral	0.327
RS1	O15537-1.2	Y177I	Pathogenic	0.991
RS1	O15537-1.2	Y177K	Pathogenic	0.986
RS1	O15537-1.2	Y177L	Pathogenic	0.993
RS1	O15537-1.2	Y177M	Pathogenic	0.997
RS1	O15537-1.2	Y177N	Pathogenic	0.996
RS1	O15537-1.2	Y177P	Pathogenic	1.0
RS1	O15537-1.2	Y177Q	Pathogenic	0.986
RS1	O15537-1.2	Y177R	Pathogenic	0.986
RS1	O15537-1.2	Y177S	Pathogenic	0.999
RS1	O15537-1.2	Y177T	Pathogenic	0.999
RS1	O15537-1.2	Y177V	Pathogenic	0.998
RS1	O15537-1.2	Y177W	Neutral	0.161
RS1	O15537-1.2	G178A	Pathogenic	0.988
RS1	O15537-1.2	G178C	Pathogenic	1.0
RS1	O15537-1.2	G178D	Pathogenic	0.997
RS1	O15537-1.2	G178E	Pathogenic	1.0
RS1	O15537-1.2	G178F	Pathogenic	1.0
RS1	O15537-1.2	G178H	Pathogenic	1.0
RS1	O15537-1.2	G178I	Pathogenic	1.0
RS1	O15537-1.2	G178K	Pathogenic	1.0
RS1	O15537-1.2	G178L	Pathogenic	1.0
RS1	O15537-1.2	G178M	Pathogenic	1.0
RS1	O15537-1.2	G178N	Pathogenic	0.987
RS1	O15537-1.2	G178P	Pathogenic	1.0
RS1	O15537-1.2	G178Q	Pathogenic	1.0
RS1	O15537-1.2	G178R	Pathogenic	1.0
RS1	O15537-1.2	G178S	Pathogenic	0.994
RS1	O15537-1.2	G178T	Pathogenic	1.0
RS1	O15537-1.2	G178V	Pathogenic	1.0
RS1	O15537-1.2	G178W	Pathogenic	0.997
RS1	O15537-1.2	G178Y	Pathogenic	1.0
RS1	O15537-1.2	N179A	Pathogenic	0.999
RS1	O15537-1.2	N179C	Pathogenic	0.999
RS1	O15537-1.2	N179D	Pathogenic	0.897
RS1	O15537-1.2	N179E	Pathogenic	0.988
RS1	O15537-1.2	N179F	Pathogenic	0.997
RS1	O15537-1.2	N179G	Pathogenic	0.979
RS1	O15537-1.2	N179H	Pathogenic	0.789
RS1	O15537-1.2	N179I	Pathogenic	0.996
RS1	O15537-1.2	N179K	Pathogenic	0.984
RS1	O15537-1.2	N179L	Pathogenic	0.997
RS1	O15537-1.2	N179M	Pathogenic	0.992
RS1	O15537-1.2	N179P	Pathogenic	0.996
RS1	O15537-1.2	N179Q	Pathogenic	0.978
RS1	O15537-1.2	N179R	Pathogenic	0.986
RS1	O15537-1.2	N179S	Pathogenic	0.841
RS1	O15537-1.2	N179T	Pathogenic	0.934
RS1	O15537-1.2	N179V	Pathogenic	0.998
RS1	O15537-1.2	N179W	Pathogenic	0.999
RS1	O15537-1.2	N179Y	Pathogenic	0.996
RS1	O15537-1.2	S180A	Pathogenic	0.718
RS1	O15537-1.2	S180C	Pathogenic	0.969
RS1	O15537-1.2	S180D	Pathogenic	0.901
RS1	O15537-1.2	S180E	Pathogenic	0.94
RS1	O15537-1.2	S180F	Pathogenic	0.988
RS1	O15537-1.2	S180G	Pathogenic	0.976
RS1	O15537-1.2	S180H	Pathogenic	0.996
RS1	O15537-1.2	S180I	Pathogenic	0.986
RS1	O15537-1.2	S180K	Pathogenic	0.92
RS1	O15537-1.2	S180L	Pathogenic	0.989
RS1	O15537-1.2	S180M	Pathogenic	0.971
RS1	O15537-1.2	S180N	Pathogenic	0.681
RS1	O15537-1.2	S180P	Pathogenic	0.982
RS1	O15537-1.2	S180Q	Pathogenic	0.974
RS1	O15537-1.2	S180R	Pathogenic	0.989
RS1	O15537-1.2	S180T	Pathogenic	0.777
RS1	O15537-1.2	S180V	Pathogenic	0.994
RS1	O15537-1.2	S180W	Pathogenic	0.997
RS1	O15537-1.2	S180Y	Pathogenic	0.998
RS1	O15537-1.2	D181A	Pathogenic	0.998
RS1	O15537-1.2	D181C	Pathogenic	0.999
RS1	O15537-1.2	D181E	Pathogenic	0.66
RS1	O15537-1.2	D181F	Pathogenic	0.996
RS1	O15537-1.2	D181G	Pathogenic	0.995
RS1	O15537-1.2	D181H	Pathogenic	0.992
RS1	O15537-1.2	D181I	Pathogenic	0.995
RS1	O15537-1.2	D181K	Pathogenic	0.998
RS1	O15537-1.2	D181L	Pathogenic	0.999
RS1	O15537-1.2	D181M	Pathogenic	0.999
RS1	O15537-1.2	D181N	Pathogenic	0.905
RS1	O15537-1.2	D181P	Pathogenic	0.965
RS1	O15537-1.2	D181Q	Pathogenic	0.974
RS1	O15537-1.2	D181R	Pathogenic	1.0
RS1	O15537-1.2	D181S	Pathogenic	0.961
RS1	O15537-1.2	D181T	Pathogenic	0.986
RS1	O15537-1.2	D181V	Pathogenic	0.998
RS1	O15537-1.2	D181W	Pathogenic	0.999
RS1	O15537-1.2	D181Y	Pathogenic	0.999
RS1	O15537-1.2	R182A	Pathogenic	0.965
RS1	O15537-1.2	R182C	Pathogenic	0.996
RS1	O15537-1.2	R182D	Pathogenic	0.999
RS1	O15537-1.2	R182E	Pathogenic	0.936
RS1	O15537-1.2	R182F	Pathogenic	0.957
RS1	O15537-1.2	R182G	Pathogenic	0.998
RS1	O15537-1.2	R182H	Pathogenic	0.737
RS1	O15537-1.2	R182I	Pathogenic	0.962
RS1	O15537-1.2	R182K	Neutral	0.322
RS1	O15537-1.2	R182L	Pathogenic	0.828
RS1	O15537-1.2	R182M	Pathogenic	0.654
RS1	O15537-1.2	R182N	Pathogenic	0.943
RS1	O15537-1.2	R182P	Pathogenic	0.982
RS1	O15537-1.2	R182Q	Neutral	0.481
RS1	O15537-1.2	R182S	Pathogenic	0.98
RS1	O15537-1.2	R182T	Pathogenic	0.954
RS1	O15537-1.2	R182V	Pathogenic	0.991
RS1	O15537-1.2	R182W	Pathogenic	0.902
RS1	O15537-1.2	R182Y	Pathogenic	0.941
RS1	O15537-1.2	T183A	Neutral	0.249
RS1	O15537-1.2	T183C	Neutral	0.297
RS1	O15537-1.2	T183D	Neutral	0.178
RS1	O15537-1.2	T183E	Neutral	0.258
RS1	O15537-1.2	T183F	Neutral	0.486
RS1	O15537-1.2	T183G	Pathogenic	0.924
RS1	O15537-1.2	T183H	Pathogenic	0.921
RS1	O15537-1.2	T183I	Neutral	0.108
RS1	O15537-1.2	T183K	Neutral	0.206
RS1	O15537-1.2	T183L	Neutral	0.129
RS1	O15537-1.2	T183M	Neutral	0.272
RS1	O15537-1.2	T183N	Neutral	0.046
RS1	O15537-1.2	T183P	Neutral	0.401
RS1	O15537-1.2	T183Q	Neutral	0.461
RS1	O15537-1.2	T183R	Neutral	0.234
RS1	O15537-1.2	T183S	Neutral	0.028
RS1	O15537-1.2	T183V	Neutral	0.043
RS1	O15537-1.2	T183W	Neutral	0.369
RS1	O15537-1.2	T183Y	Pathogenic	0.841
RS1	O15537-1.2	S184A	Pathogenic	0.781
RS1	O15537-1.2	S184C	Pathogenic	0.978
RS1	O15537-1.2	S184D	Pathogenic	0.928
RS1	O15537-1.2	S184E	Pathogenic	0.956
RS1	O15537-1.2	S184F	Pathogenic	0.992
RS1	O15537-1.2	S184G	Pathogenic	0.982
RS1	O15537-1.2	S184H	Pathogenic	0.997
RS1	O15537-1.2	S184I	Pathogenic	0.99
RS1	O15537-1.2	S184K	Pathogenic	0.942
RS1	O15537-1.2	S184L	Pathogenic	0.992
RS1	O15537-1.2	S184M	Pathogenic	0.979
RS1	O15537-1.2	S184N	Pathogenic	0.75
RS1	O15537-1.2	S184P	Pathogenic	0.987
RS1	O15537-1.2	S184Q	Pathogenic	0.982
RS1	O15537-1.2	S184R	Pathogenic	0.992
RS1	O15537-1.2	S184T	Pathogenic	0.83
RS1	O15537-1.2	S184V	Pathogenic	0.996
RS1	O15537-1.2	S184W	Pathogenic	0.998
RS1	O15537-1.2	S184Y	Pathogenic	0.999
RS1	O15537-1.2	T185A	Neutral	0.091
RS1	O15537-1.2	T185C	Neutral	0.113
RS1	O15537-1.2	T185D	Neutral	0.061
RS1	O15537-1.2	T185E	Neutral	0.095
RS1	O15537-1.2	T185F	Neutral	0.222
RS1	O15537-1.2	T185G	Pathogenic	0.786
RS1	O15537-1.2	T185H	Pathogenic	0.779
RS1	O15537-1.2	T185I	Neutral	0.035
RS1	O15537-1.2	T185K	Neutral	0.072
RS1	O15537-1.2	T185L	Neutral	0.043
RS1	O15537-1.2	T185M	Neutral	0.101
RS1	O15537-1.2	T185N	Neutral	0.014
RS1	O15537-1.2	T185P	Neutral	0.168
RS1	O15537-1.2	T185Q	Neutral	0.205
RS1	O15537-1.2	T185R	Neutral	0.085
RS1	O15537-1.2	T185S	Neutral	0.009
RS1	O15537-1.2	T185V	Neutral	0.013
RS1	O15537-1.2	T185W	Neutral	0.15
RS1	O15537-1.2	T185Y	Pathogenic	0.615
RS1	O15537-1.2	V186A	Pathogenic	0.968
RS1	O15537-1.2	V186C	Pathogenic	0.998
RS1	O15537-1.2	V186D	Pathogenic	0.998
RS1	O15537-1.2	V186E	Pathogenic	0.991
RS1	O15537-1.2	V186F	Pathogenic	0.997
RS1	O15537-1.2	V186G	Pathogenic	1.0
RS1	O15537-1.2	V186H	Pathogenic	1.0
RS1	O15537-1.2	V186I	Neutral	0.137
RS1	O15537-1.2	V186K	Pathogenic	0.988
RS1	O15537-1.2	V186L	Pathogenic	0.89
RS1	O15537-1.2	V186M	Pathogenic	0.953
RS1	O15537-1.2	V186N	Pathogenic	0.999
RS1	O15537-1.2	V186P	Pathogenic	0.999
RS1	O15537-1.2	V186Q	Pathogenic	0.996
RS1	O15537-1.2	V186R	Pathogenic	0.998
RS1	O15537-1.2	V186S	Pathogenic	0.998
RS1	O15537-1.2	V186T	Pathogenic	0.948
RS1	O15537-1.2	V186W	Pathogenic	1.0
RS1	O15537-1.2	V186Y	Pathogenic	0.999
RS1	O15537-1.2	Q187A	Pathogenic	0.999
RS1	O15537-1.2	Q187C	Pathogenic	1.0
RS1	O15537-1.2	Q187D	Pathogenic	0.991
RS1	O15537-1.2	Q187E	Pathogenic	0.735
RS1	O15537-1.2	Q187F	Pathogenic	0.999
RS1	O15537-1.2	Q187G	Pathogenic	1.0
RS1	O15537-1.2	Q187H	Pathogenic	0.992
RS1	O15537-1.2	Q187I	Pathogenic	0.999
RS1	O15537-1.2	Q187K	Pathogenic	0.919
RS1	O15537-1.2	Q187L	Pathogenic	0.996
RS1	O15537-1.2	Q187M	Pathogenic	0.942
RS1	O15537-1.2	Q187N	Pathogenic	0.993
RS1	O15537-1.2	Q187P	Pathogenic	0.997
RS1	O15537-1.2	Q187R	Pathogenic	0.931
RS1	O15537-1.2	Q187S	Pathogenic	0.997
RS1	O15537-1.2	Q187T	Pathogenic	0.999
RS1	O15537-1.2	Q187V	Pathogenic	0.999
RS1	O15537-1.2	Q187W	Pathogenic	0.994
RS1	O15537-1.2	Q187Y	Pathogenic	0.996
RS1	O15537-1.2	N188A	Pathogenic	0.997
RS1	O15537-1.2	N188C	Pathogenic	0.997
RS1	O15537-1.2	N188D	Pathogenic	0.773
RS1	O15537-1.2	N188E	Pathogenic	0.97
RS1	O15537-1.2	N188F	Pathogenic	0.992
RS1	O15537-1.2	N188G	Pathogenic	0.947
RS1	O15537-1.2	N188H	Pathogenic	0.593
RS1	O15537-1.2	N188I	Pathogenic	0.99
RS1	O15537-1.2	N188K	Pathogenic	0.96
RS1	O15537-1.2	N188L	Pathogenic	0.992
RS1	O15537-1.2	N188M	Pathogenic	0.98
RS1	O15537-1.2	N188P	Pathogenic	0.99
RS1	O15537-1.2	N188Q	Pathogenic	0.946
RS1	O15537-1.2	N188R	Pathogenic	0.966
RS1	O15537-1.2	N188S	Pathogenic	0.673
RS1	O15537-1.2	N188T	Pathogenic	0.846
RS1	O15537-1.2	N188V	Pathogenic	0.996
RS1	O15537-1.2	N188W	Pathogenic	0.998
RS1	O15537-1.2	N188Y	Pathogenic	0.991
RS1	O15537-1.2	L189A	Pathogenic	0.968
RS1	O15537-1.2	L189C	Pathogenic	0.989
RS1	O15537-1.2	L189D	Pathogenic	0.999
RS1	O15537-1.2	L189E	Pathogenic	0.991
RS1	O15537-1.2	L189F	Pathogenic	0.969
RS1	O15537-1.2	L189G	Pathogenic	1.0
RS1	O15537-1.2	L189H	Pathogenic	0.998
RS1	O15537-1.2	L189I	Neutral	0.381
RS1	O15537-1.2	L189K	Pathogenic	0.884
RS1	O15537-1.2	L189M	Neutral	0.23
RS1	O15537-1.2	L189N	Pathogenic	0.993
RS1	O15537-1.2	L189P	Pathogenic	1.0
RS1	O15537-1.2	L189Q	Pathogenic	0.972
RS1	O15537-1.2	L189R	Pathogenic	0.9
RS1	O15537-1.2	L189S	Pathogenic	0.989
RS1	O15537-1.2	L189T	Pathogenic	0.949
RS1	O15537-1.2	L189V	Pathogenic	0.714
RS1	O15537-1.2	L189W	Pathogenic	0.999
RS1	O15537-1.2	L189Y	Pathogenic	0.984
RS1	O15537-1.2	L190A	Pathogenic	0.995
RS1	O15537-1.2	L190C	Pathogenic	0.998
RS1	O15537-1.2	L190D	Pathogenic	1.0
RS1	O15537-1.2	L190E	Pathogenic	0.999
RS1	O15537-1.2	L190F	Pathogenic	0.995
RS1	O15537-1.2	L190G	Pathogenic	1.0
RS1	O15537-1.2	L190H	Pathogenic	1.0
RS1	O15537-1.2	L190I	Pathogenic	0.802
RS1	O15537-1.2	L190K	Pathogenic	0.981
RS1	O15537-1.2	L190M	Pathogenic	0.664
RS1	O15537-1.2	L190N	Pathogenic	0.999
RS1	O15537-1.2	L190P	Pathogenic	1.0
RS1	O15537-1.2	L190Q	Pathogenic	0.996
RS1	O15537-1.2	L190R	Pathogenic	0.984
RS1	O15537-1.2	L190S	Pathogenic	0.998
RS1	O15537-1.2	L190T	Pathogenic	0.992
RS1	O15537-1.2	L190V	Pathogenic	0.943
RS1	O15537-1.2	L190W	Pathogenic	1.0
RS1	O15537-1.2	L190Y	Pathogenic	0.997
RS1	O15537-1.2	R191A	Pathogenic	0.996
RS1	O15537-1.2	R191C	Pathogenic	0.999
RS1	O15537-1.2	R191D	Pathogenic	1.0
RS1	O15537-1.2	R191E	Pathogenic	0.992
RS1	O15537-1.2	R191F	Pathogenic	0.995
RS1	O15537-1.2	R191G	Pathogenic	1.0
RS1	O15537-1.2	R191H	Pathogenic	0.958
RS1	O15537-1.2	R191I	Pathogenic	0.995
RS1	O15537-1.2	R191K	Pathogenic	0.797
RS1	O15537-1.2	R191L	Pathogenic	0.975
RS1	O15537-1.2	R191M	Pathogenic	0.94
RS1	O15537-1.2	R191N	Pathogenic	0.993
RS1	O15537-1.2	R191P	Pathogenic	0.998
RS1	O15537-1.2	R191Q	Pathogenic	0.884
RS1	O15537-1.2	R191S	Pathogenic	0.998
RS1	O15537-1.2	R191T	Pathogenic	0.994
RS1	O15537-1.2	R191V	Pathogenic	0.999
RS1	O15537-1.2	R191W	Pathogenic	0.987
RS1	O15537-1.2	R191Y	Pathogenic	0.992
RS1	O15537-1.2	P192A	Pathogenic	0.999
RS1	O15537-1.2	P192C	Pathogenic	1.0
RS1	O15537-1.2	P192D	Pathogenic	0.987
RS1	O15537-1.2	P192E	Pathogenic	0.992
RS1	O15537-1.2	P192F	Pathogenic	1.0
RS1	O15537-1.2	P192G	Pathogenic	1.0
RS1	O15537-1.2	P192H	Pathogenic	1.0
RS1	O15537-1.2	P192I	Pathogenic	1.0
RS1	O15537-1.2	P192K	Pathogenic	0.989
RS1	O15537-1.2	P192L	Pathogenic	1.0
RS1	O15537-1.2	P192M	Pathogenic	1.0
RS1	O15537-1.2	P192N	Pathogenic	0.999
RS1	O15537-1.2	P192Q	Pathogenic	0.997
RS1	O15537-1.2	P192R	Pathogenic	0.999
RS1	O15537-1.2	P192S	Pathogenic	0.998
RS1	O15537-1.2	P192T	Pathogenic	0.998
RS1	O15537-1.2	P192V	Pathogenic	1.0
RS1	O15537-1.2	P192W	Pathogenic	1.0
RS1	O15537-1.2	P192Y	Pathogenic	1.0
RS1	O15537-1.2	P193A	Pathogenic	0.997
RS1	O15537-1.2	P193C	Pathogenic	1.0
RS1	O15537-1.2	P193D	Pathogenic	0.972
RS1	O15537-1.2	P193E	Pathogenic	0.983
RS1	O15537-1.2	P193F	Pathogenic	1.0
RS1	O15537-1.2	P193G	Pathogenic	0.999
RS1	O15537-1.2	P193H	Pathogenic	0.999
RS1	O15537-1.2	P193I	Pathogenic	1.0
RS1	O15537-1.2	P193K	Pathogenic	0.977
RS1	O15537-1.2	P193L	Pathogenic	1.0
RS1	O15537-1.2	P193M	Pathogenic	1.0
RS1	O15537-1.2	P193N	Pathogenic	0.997
RS1	O15537-1.2	P193Q	Pathogenic	0.993
RS1	O15537-1.2	P193R	Pathogenic	0.997
RS1	O15537-1.2	P193S	Pathogenic	0.995
RS1	O15537-1.2	P193T	Pathogenic	0.996
RS1	O15537-1.2	P193V	Pathogenic	0.999
RS1	O15537-1.2	P193W	Pathogenic	1.0
RS1	O15537-1.2	P193Y	Pathogenic	1.0
RS1	O15537-1.2	I194A	Pathogenic	0.989
RS1	O15537-1.2	I194C	Pathogenic	0.996
RS1	O15537-1.2	I194D	Pathogenic	0.997
RS1	O15537-1.2	I194E	Pathogenic	0.997
RS1	O15537-1.2	I194F	Pathogenic	0.992
RS1	O15537-1.2	I194G	Pathogenic	1.0
RS1	O15537-1.2	I194H	Pathogenic	0.999
RS1	O15537-1.2	I194K	Pathogenic	0.993
RS1	O15537-1.2	I194L	Pathogenic	0.685
RS1	O15537-1.2	I194M	Pathogenic	0.847
RS1	O15537-1.2	I194N	Pathogenic	0.997
RS1	O15537-1.2	I194P	Pathogenic	1.0
RS1	O15537-1.2	I194Q	Pathogenic	0.998
RS1	O15537-1.2	I194R	Pathogenic	0.994
RS1	O15537-1.2	I194S	Pathogenic	0.996
RS1	O15537-1.2	I194T	Pathogenic	0.982
RS1	O15537-1.2	I194V	Neutral	0.148
RS1	O15537-1.2	I194W	Pathogenic	1.0
RS1	O15537-1.2	I194Y	Pathogenic	0.994
RS1	O15537-1.2	I195A	Neutral	0.198
RS1	O15537-1.2	I195C	Neutral	0.41
RS1	O15537-1.2	I195D	Neutral	0.459
RS1	O15537-1.2	I195E	Neutral	0.455
RS1	O15537-1.2	I195F	Neutral	0.26
RS1	O15537-1.2	I195G	Pathogenic	0.979
RS1	O15537-1.2	I195H	Pathogenic	0.768
RS1	O15537-1.2	I195K	Neutral	0.282
RS1	O15537-1.2	I195L	Neutral	0.006
RS1	O15537-1.2	I195M	Neutral	0.015
RS1	O15537-1.2	I195N	Pathogenic	0.522
RS1	O15537-1.2	I195P	Pathogenic	0.941
RS1	O15537-1.2	I195Q	Pathogenic	0.638
RS1	O15537-1.2	I195R	Neutral	0.318
RS1	O15537-1.2	I195S	Neutral	0.423
RS1	O15537-1.2	I195T	Neutral	0.13
RS1	O15537-1.2	I195V	Neutral	0.0
RS1	O15537-1.2	I195W	Pathogenic	0.984
RS1	O15537-1.2	I195Y	Neutral	0.326
RS1	O15537-1.2	S196A	Neutral	0.023
RS1	O15537-1.2	S196C	Neutral	0.221
RS1	O15537-1.2	S196D	Neutral	0.077
RS1	O15537-1.2	S196E	Neutral	0.125
RS1	O15537-1.2	S196F	Neutral	0.44
RS1	O15537-1.2	S196G	Neutral	0.268
RS1	O15537-1.2	S196H	Pathogenic	0.711
RS1	O15537-1.2	S196I	Neutral	0.392
RS1	O15537-1.2	S196K	Neutral	0.096
RS1	O15537-1.2	S196L	Neutral	0.441
RS1	O15537-1.2	S196M	Neutral	0.237
RS1	O15537-1.2	S196N	Neutral	0.019
RS1	O15537-1.2	S196P	Neutral	0.336
RS1	O15537-1.2	S196Q	Neutral	0.259
RS1	O15537-1.2	S196R	Neutral	0.446
RS1	O15537-1.2	S196T	Neutral	0.031
RS1	O15537-1.2	S196V	Pathogenic	0.605
RS1	O15537-1.2	S196W	Pathogenic	0.757
RS1	O15537-1.2	S196Y	Pathogenic	0.814
RS1	O15537-1.2	R197A	Pathogenic	0.986
RS1	O15537-1.2	R197C	Pathogenic	0.998
RS1	O15537-1.2	R197D	Pathogenic	1.0
RS1	O15537-1.2	R197E	Pathogenic	0.974
RS1	O15537-1.2	R197F	Pathogenic	0.983
RS1	O15537-1.2	R197G	Pathogenic	0.999
RS1	O15537-1.2	R197H	Pathogenic	0.877
RS1	O15537-1.2	R197I	Pathogenic	0.985
RS1	O15537-1.2	R197K	Pathogenic	0.548
RS1	O15537-1.2	R197L	Pathogenic	0.925
RS1	O15537-1.2	R197M	Pathogenic	0.828
RS1	O15537-1.2	R197N	Pathogenic	0.977
RS1	O15537-1.2	R197P	Pathogenic	0.993
RS1	O15537-1.2	R197Q	Pathogenic	0.703
RS1	O15537-1.2	R197S	Pathogenic	0.992
RS1	O15537-1.2	R197T	Pathogenic	0.981
RS1	O15537-1.2	R197V	Pathogenic	0.996
RS1	O15537-1.2	R197W	Pathogenic	0.959
RS1	O15537-1.2	R197Y	Pathogenic	0.976
RS1	O15537-1.2	F198A	Neutral	0.268
RS1	O15537-1.2	F198C	Pathogenic	0.508
RS1	O15537-1.2	F198D	Neutral	0.164
RS1	O15537-1.2	F198E	Neutral	0.162
RS1	O15537-1.2	F198G	Pathogenic	0.631
RS1	O15537-1.2	F198H	Neutral	0.018
RS1	O15537-1.2	F198I	Neutral	0.062
RS1	O15537-1.2	F198K	Neutral	0.061
RS1	O15537-1.2	F198L	Neutral	0.054
RS1	O15537-1.2	F198M	Neutral	0.022
RS1	O15537-1.2	F198N	Neutral	0.202
RS1	O15537-1.2	F198P	Pathogenic	0.96
RS1	O15537-1.2	F198Q	Neutral	0.289
RS1	O15537-1.2	F198R	Neutral	0.071
RS1	O15537-1.2	F198S	Neutral	0.145
RS1	O15537-1.2	F198T	Neutral	0.182
RS1	O15537-1.2	F198V	Neutral	0.16
RS1	O15537-1.2	F198W	Neutral	0.006
RS1	O15537-1.2	F198Y	Neutral	0.0
RS1	O15537-1.2	I199A	Pathogenic	0.962
RS1	O15537-1.2	I199C	Pathogenic	0.986
RS1	O15537-1.2	I199D	Pathogenic	0.989
RS1	O15537-1.2	I199E	Pathogenic	0.988
RS1	O15537-1.2	I199F	Pathogenic	0.973
RS1	O15537-1.2	I199G	Pathogenic	1.0
RS1	O15537-1.2	I199H	Pathogenic	0.997
RS1	O15537-1.2	I199K	Pathogenic	0.976
RS1	O15537-1.2	I199L	Neutral	0.382
RS1	O15537-1.2	I199M	Pathogenic	0.612
RS1	O15537-1.2	I199N	Pathogenic	0.991
RS1	O15537-1.2	I199P	Pathogenic	0.999
RS1	O15537-1.2	I199Q	Pathogenic	0.995
RS1	O15537-1.2	I199R	Pathogenic	0.98
RS1	O15537-1.2	I199S	Pathogenic	0.987
RS1	O15537-1.2	I199T	Pathogenic	0.939
RS1	O15537-1.2	I199V	Neutral	0.047
RS1	O15537-1.2	I199W	Pathogenic	1.0
RS1	O15537-1.2	I199Y	Pathogenic	0.98
RS1	O15537-1.2	R200A	Pathogenic	0.988
RS1	O15537-1.2	R200C	Pathogenic	0.999
RS1	O15537-1.2	R200D	Pathogenic	1.0
RS1	O15537-1.2	R200E	Pathogenic	0.978
RS1	O15537-1.2	R200F	Pathogenic	0.985
RS1	O15537-1.2	R200G	Pathogenic	0.999
RS1	O15537-1.2	R200H	Pathogenic	0.895
RS1	O15537-1.2	R200I	Pathogenic	0.987
RS1	O15537-1.2	R200K	Pathogenic	0.592
RS1	O15537-1.2	R200L	Pathogenic	0.936
RS1	O15537-1.2	R200M	Pathogenic	0.852
RS1	O15537-1.2	R200N	Pathogenic	0.981
RS1	O15537-1.2	R200P	Pathogenic	0.994
RS1	O15537-1.2	R200Q	Pathogenic	0.738
RS1	O15537-1.2	R200S	Pathogenic	0.993
RS1	O15537-1.2	R200T	Pathogenic	0.984
RS1	O15537-1.2	R200V	Pathogenic	0.997
RS1	O15537-1.2	R200W	Pathogenic	0.965
RS1	O15537-1.2	R200Y	Pathogenic	0.98
RS1	O15537-1.2	L201A	Pathogenic	0.645
RS1	O15537-1.2	L201C	Pathogenic	0.837
RS1	O15537-1.2	L201D	Pathogenic	0.976
RS1	O15537-1.2	L201E	Pathogenic	0.86
RS1	O15537-1.2	L201F	Pathogenic	0.647
RS1	O15537-1.2	L201G	Pathogenic	0.997
RS1	O15537-1.2	L201H	Pathogenic	0.961
RS1	O15537-1.2	L201I	Neutral	0.035
RS1	O15537-1.2	L201K	Neutral	0.311
RS1	O15537-1.2	L201M	Neutral	0.017
RS1	O15537-1.2	L201N	Pathogenic	0.89
RS1	O15537-1.2	L201P	Pathogenic	0.992
RS1	O15537-1.2	L201Q	Pathogenic	0.669
RS1	O15537-1.2	L201R	Neutral	0.348
RS1	O15537-1.2	L201S	Pathogenic	0.844
RS1	O15537-1.2	L201T	Pathogenic	0.525
RS1	O15537-1.2	L201V	Neutral	0.129
RS1	O15537-1.2	L201W	Pathogenic	0.979
RS1	O15537-1.2	L201Y	Pathogenic	0.781
RS1	O15537-1.2	I202A	Neutral	0.027
RS1	O15537-1.2	I202C	Neutral	0.073
RS1	O15537-1.2	I202D	Neutral	0.088
RS1	O15537-1.2	I202E	Neutral	0.087
RS1	O15537-1.2	I202F	Neutral	0.038
RS1	O15537-1.2	I202G	Pathogenic	0.844
RS1	O15537-1.2	I202H	Neutral	0.273
RS1	O15537-1.2	I202K	Neutral	0.043
RS1	O15537-1.2	I202L	Neutral	0.001
RS1	O15537-1.2	I202M	Neutral	0.002
RS1	O15537-1.2	I202N	Neutral	0.11
RS1	O15537-1.2	I202P	Pathogenic	0.646
RS1	O15537-1.2	I202Q	Neutral	0.166
RS1	O15537-1.2	I202R	Neutral	0.05
RS1	O15537-1.2	I202S	Neutral	0.077
RS1	O15537-1.2	I202T	Neutral	0.017
RS1	O15537-1.2	I202V	Neutral	0.0
RS1	O15537-1.2	I202W	Pathogenic	0.873
RS1	O15537-1.2	I202Y	Neutral	0.052
RS1	O15537-1.2	P203A	Pathogenic	0.997
RS1	O15537-1.2	P203C	Pathogenic	1.0
RS1	O15537-1.2	P203D	Pathogenic	0.967
RS1	O15537-1.2	P203E	Pathogenic	0.98
RS1	O15537-1.2	P203F	Pathogenic	1.0
RS1	O15537-1.2	P203G	Pathogenic	0.999
RS1	O15537-1.2	P203H	Pathogenic	0.999
RS1	O15537-1.2	P203I	Pathogenic	1.0
RS1	O15537-1.2	P203K	Pathogenic	0.974
RS1	O15537-1.2	P203L	Pathogenic	1.0
RS1	O15537-1.2	P203M	Pathogenic	1.0
RS1	O15537-1.2	P203N	Pathogenic	0.996
RS1	O15537-1.2	P203Q	Pathogenic	0.992
RS1	O15537-1.2	P203R	Pathogenic	0.996
RS1	O15537-1.2	P203S	Pathogenic	0.994
RS1	O15537-1.2	P203T	Pathogenic	0.996
RS1	O15537-1.2	P203V	Pathogenic	0.999
RS1	O15537-1.2	P203W	Pathogenic	1.0
RS1	O15537-1.2	P203Y	Pathogenic	1.0
RS1	O15537-1.2	L204A	Pathogenic	0.99
RS1	O15537-1.2	L204C	Pathogenic	0.996
RS1	O15537-1.2	L204D	Pathogenic	1.0
RS1	O15537-1.2	L204E	Pathogenic	0.997
RS1	O15537-1.2	L204F	Pathogenic	0.99
RS1	O15537-1.2	L204G	Pathogenic	1.0
RS1	O15537-1.2	L204H	Pathogenic	0.999
RS1	O15537-1.2	L204I	Pathogenic	0.654
RS1	O15537-1.2	L204K	Pathogenic	0.959
RS1	O15537-1.2	L204M	Neutral	0.479
RS1	O15537-1.2	L204N	Pathogenic	0.998
RS1	O15537-1.2	L204P	Pathogenic	1.0
RS1	O15537-1.2	L204Q	Pathogenic	0.991
RS1	O15537-1.2	L204R	Pathogenic	0.965
RS1	O15537-1.2	L204S	Pathogenic	0.996
RS1	O15537-1.2	L204T	Pathogenic	0.983
RS1	O15537-1.2	L204V	Pathogenic	0.885
RS1	O15537-1.2	L204W	Pathogenic	1.0
RS1	O15537-1.2	L204Y	Pathogenic	0.995
RS1	O15537-1.2	G205A	Pathogenic	0.985
RS1	O15537-1.2	G205C	Pathogenic	1.0
RS1	O15537-1.2	G205D	Pathogenic	0.996
RS1	O15537-1.2	G205E	Pathogenic	1.0
RS1	O15537-1.2	G205F	Pathogenic	1.0
RS1	O15537-1.2	G205H	Pathogenic	1.0
RS1	O15537-1.2	G205I	Pathogenic	1.0
RS1	O15537-1.2	G205K	Pathogenic	1.0
RS1	O15537-1.2	G205L	Pathogenic	1.0
RS1	O15537-1.2	G205M	Pathogenic	1.0
RS1	O15537-1.2	G205N	Pathogenic	0.983
RS1	O15537-1.2	G205P	Pathogenic	0.999
RS1	O15537-1.2	G205Q	Pathogenic	1.0
RS1	O15537-1.2	G205R	Pathogenic	1.0
RS1	O15537-1.2	G205S	Pathogenic	0.992
RS1	O15537-1.2	G205T	Pathogenic	1.0
RS1	O15537-1.2	G205V	Pathogenic	1.0
RS1	O15537-1.2	G205W	Pathogenic	0.996
RS1	O15537-1.2	G205Y	Pathogenic	1.0
RS1	O15537-1.2	W206A	Pathogenic	0.998
RS1	O15537-1.2	W206C	Pathogenic	0.996
RS1	O15537-1.2	W206D	Pathogenic	0.997
RS1	O15537-1.2	W206E	Pathogenic	0.98
RS1	O15537-1.2	W206F	Pathogenic	0.694
RS1	O15537-1.2	W206G	Pathogenic	0.985
RS1	O15537-1.2	W206H	Pathogenic	0.968
RS1	O15537-1.2	W206I	Pathogenic	1.0
RS1	O15537-1.2	W206K	Pathogenic	0.943
RS1	O15537-1.2	W206L	Pathogenic	0.998
RS1	O15537-1.2	W206M	Pathogenic	0.974
RS1	O15537-1.2	W206N	Pathogenic	0.998
RS1	O15537-1.2	W206P	Pathogenic	1.0
RS1	O15537-1.2	W206Q	Pathogenic	0.941
RS1	O15537-1.2	W206R	Pathogenic	0.929
RS1	O15537-1.2	W206S	Pathogenic	0.996
RS1	O15537-1.2	W206T	Pathogenic	0.982
RS1	O15537-1.2	W206V	Pathogenic	0.999
RS1	O15537-1.2	W206Y	Neutral	0.059
RS1	O15537-1.2	H207A	Pathogenic	1.0
RS1	O15537-1.2	H207C	Pathogenic	1.0
RS1	O15537-1.2	H207D	Pathogenic	0.988
RS1	O15537-1.2	H207E	Pathogenic	0.929
RS1	O15537-1.2	H207F	Pathogenic	0.944
RS1	O15537-1.2	H207G	Pathogenic	1.0
RS1	O15537-1.2	H207I	Pathogenic	0.998
RS1	O15537-1.2	H207K	Pathogenic	0.98
RS1	O15537-1.2	H207L	Pathogenic	0.999
RS1	O15537-1.2	H207M	Pathogenic	0.996
RS1	O15537-1.2	H207N	Pathogenic	0.728
RS1	O15537-1.2	H207P	Pathogenic	0.999
RS1	O15537-1.2	H207Q	Pathogenic	0.965
RS1	O15537-1.2	H207R	Pathogenic	0.898
RS1	O15537-1.2	H207S	Pathogenic	0.998
RS1	O15537-1.2	H207T	Pathogenic	1.0
RS1	O15537-1.2	H207V	Pathogenic	1.0
RS1	O15537-1.2	H207W	Pathogenic	0.985
RS1	O15537-1.2	H207Y	Neutral	0.259
RS1	O15537-1.2	V208A	Neutral	0.037
RS1	O15537-1.2	V208C	Neutral	0.41
RS1	O15537-1.2	V208D	Neutral	0.459
RS1	O15537-1.2	V208E	Neutral	0.128
RS1	O15537-1.2	V208F	Neutral	0.298
RS1	O15537-1.2	V208G	Pathogenic	0.881
RS1	O15537-1.2	V208H	Pathogenic	0.831
RS1	O15537-1.2	V208I	Neutral	0.0
RS1	O15537-1.2	V208K	Neutral	0.098
RS1	O15537-1.2	V208L	Neutral	0.01
RS1	O15537-1.2	V208M	Neutral	0.025
RS1	O15537-1.2	V208N	Pathogenic	0.523
RS1	O15537-1.2	V208P	Pathogenic	0.715
RS1	O15537-1.2	V208Q	Neutral	0.265
RS1	O15537-1.2	V208R	Neutral	0.454
RS1	O15537-1.2	V208S	Neutral	0.423
RS1	O15537-1.2	V208T	Neutral	0.023
RS1	O15537-1.2	V208W	Pathogenic	0.915
RS1	O15537-1.2	V208Y	Neutral	0.463
RS1	O15537-1.2	R209A	Pathogenic	0.991
RS1	O15537-1.2	R209C	Pathogenic	0.999
RS1	O15537-1.2	R209D	Pathogenic	1.0
RS1	O15537-1.2	R209E	Pathogenic	0.982
RS1	O15537-1.2	R209F	Pathogenic	0.988
RS1	O15537-1.2	R209G	Pathogenic	0.999
RS1	O15537-1.2	R209H	Pathogenic	0.915
RS1	O15537-1.2	R209I	Pathogenic	0.99
RS1	O15537-1.2	R209K	Pathogenic	0.646
RS1	O15537-1.2	R209L	Pathogenic	0.949
RS1	O15537-1.2	R209M	Pathogenic	0.879
RS1	O15537-1.2	R209N	Pathogenic	0.984
RS1	O15537-1.2	R209P	Pathogenic	0.995
RS1	O15537-1.2	R209Q	Pathogenic	0.78
RS1	O15537-1.2	R209S	Pathogenic	0.995
RS1	O15537-1.2	R209T	Pathogenic	0.988
RS1	O15537-1.2	R209V	Pathogenic	0.998
RS1	O15537-1.2	R209W	Pathogenic	0.972
RS1	O15537-1.2	R209Y	Pathogenic	0.984
RS1	O15537-1.2	I210A	Pathogenic	0.777
RS1	O15537-1.2	I210C	Pathogenic	0.908
RS1	O15537-1.2	I210D	Pathogenic	0.923
RS1	O15537-1.2	I210E	Pathogenic	0.922
RS1	O15537-1.2	I210F	Pathogenic	0.833
RS1	O15537-1.2	I210G	Pathogenic	0.999
RS1	O15537-1.2	I210H	Pathogenic	0.979
RS1	O15537-1.2	I210K	Pathogenic	0.848
RS1	O15537-1.2	I210L	Neutral	0.079
RS1	O15537-1.2	I210M	Neutral	0.179
RS1	O15537-1.2	I210N	Pathogenic	0.94
RS1	O15537-1.2	I210P	Pathogenic	0.996
RS1	O15537-1.2	I210Q	Pathogenic	0.962
RS1	O15537-1.2	I210R	Pathogenic	0.869
RS1	O15537-1.2	I210S	Pathogenic	0.912
RS1	O15537-1.2	I210T	Pathogenic	0.68
RS1	O15537-1.2	I210V	Neutral	0.007
RS1	O15537-1.2	I210W	Pathogenic	0.999
RS1	O15537-1.2	I210Y	Pathogenic	0.873
RS1	O15537-1.2	A211C	Pathogenic	0.954
RS1	O15537-1.2	A211D	Pathogenic	0.998
RS1	O15537-1.2	A211E	Pathogenic	0.991
RS1	O15537-1.2	A211F	Pathogenic	0.997
RS1	O15537-1.2	A211G	Pathogenic	0.977
RS1	O15537-1.2	A211H	Pathogenic	1.0
RS1	O15537-1.2	A211I	Pathogenic	0.979
RS1	O15537-1.2	A211K	Pathogenic	0.988
RS1	O15537-1.2	A211L	Pathogenic	0.983
RS1	O15537-1.2	A211M	Pathogenic	0.993
RS1	O15537-1.2	A211N	Pathogenic	0.998
RS1	O15537-1.2	A211P	Pathogenic	0.996
RS1	O15537-1.2	A211Q	Pathogenic	0.996
RS1	O15537-1.2	A211R	Pathogenic	0.99
RS1	O15537-1.2	A211S	Pathogenic	0.835
RS1	O15537-1.2	A211T	Pathogenic	0.987
RS1	O15537-1.2	A211V	Pathogenic	0.946
RS1	O15537-1.2	A211W	Pathogenic	0.999
RS1	O15537-1.2	A211Y	Pathogenic	1.0
RS1	O15537-1.2	I212A	Neutral	0.009
RS1	O15537-1.2	I212C	Neutral	0.025
RS1	O15537-1.2	I212D	Neutral	0.03
RS1	O15537-1.2	I212E	Neutral	0.03
RS1	O15537-1.2	I212F	Neutral	0.013
RS1	O15537-1.2	I212G	Pathogenic	0.636
RS1	O15537-1.2	I212H	Neutral	0.108
RS1	O15537-1.2	I212K	Neutral	0.014
RS1	O15537-1.2	I212L	Neutral	0.0
RS1	O15537-1.2	I212M	Neutral	0.001
RS1	O15537-1.2	I212N	Neutral	0.039
RS1	O15537-1.2	I212P	Neutral	0.371
RS1	O15537-1.2	I212Q	Neutral	0.061
RS1	O15537-1.2	I212R	Neutral	0.017
RS1	O15537-1.2	I212S	Neutral	0.026
RS1	O15537-1.2	I212T	Neutral	0.005
RS1	O15537-1.2	I212V	Neutral	0.0
RS1	O15537-1.2	I212W	Pathogenic	0.691
RS1	O15537-1.2	I212Y	Neutral	0.017
RS1	O15537-1.2	R213A	Pathogenic	0.994
RS1	O15537-1.2	R213C	Pathogenic	0.999
RS1	O15537-1.2	R213D	Pathogenic	1.0
RS1	O15537-1.2	R213E	Pathogenic	0.988
RS1	O15537-1.2	R213F	Pathogenic	0.992
RS1	O15537-1.2	R213G	Pathogenic	1.0
RS1	O15537-1.2	R213H	Pathogenic	0.94
RS1	O15537-1.2	R213I	Pathogenic	0.993
RS1	O15537-1.2	R213K	Pathogenic	0.727
RS1	O15537-1.2	R213L	Pathogenic	0.964
RS1	O15537-1.2	R213M	Pathogenic	0.914
RS1	O15537-1.2	R213N	Pathogenic	0.989
RS1	O15537-1.2	R213P	Pathogenic	0.997
RS1	O15537-1.2	R213Q	Pathogenic	0.838
RS1	O15537-1.2	R213S	Pathogenic	0.996
RS1	O15537-1.2	R213T	Pathogenic	0.991
RS1	O15537-1.2	R213V	Pathogenic	0.998
RS1	O15537-1.2	R213W	Pathogenic	0.981
RS1	O15537-1.2	R213Y	Pathogenic	0.989
RS1	O15537-1.2	M214A	Pathogenic	0.557
RS1	O15537-1.2	M214C	Pathogenic	0.781
RS1	O15537-1.2	M214D	Pathogenic	0.813
RS1	O15537-1.2	M214E	Neutral	0.399
RS1	O15537-1.2	M214F	Neutral	0.167
RS1	O15537-1.2	M214G	Pathogenic	0.974
RS1	O15537-1.2	M214H	Pathogenic	0.726
RS1	O15537-1.2	M214I	Neutral	0.025
RS1	O15537-1.2	M214K	Neutral	0.046
RS1	O15537-1.2	M214L	Neutral	0.005
RS1	O15537-1.2	M214N	Neutral	0.466
RS1	O15537-1.2	M214P	Pathogenic	0.928
RS1	O15537-1.2	M214Q	Neutral	0.033
RS1	O15537-1.2	M214R	Neutral	0.054
RS1	O15537-1.2	M214S	Neutral	0.368
RS1	O15537-1.2	M214T	Neutral	0.434
RS1	O15537-1.2	M214V	Neutral	0.093
RS1	O15537-1.2	M214W	Neutral	0.443
RS1	O15537-1.2	M214Y	Pathogenic	0.713
RS1	O15537-1.2	E215A	Pathogenic	0.995
RS1	O15537-1.2	E215C	Pathogenic	1.0
RS1	O15537-1.2	E215D	Pathogenic	0.706
RS1	O15537-1.2	E215F	Pathogenic	0.997
RS1	O15537-1.2	E215G	Pathogenic	1.0
RS1	O15537-1.2	E215H	Pathogenic	0.961
RS1	O15537-1.2	E215I	Pathogenic	0.996
RS1	O15537-1.2	E215K	Pathogenic	0.919
RS1	O15537-1.2	E215L	Pathogenic	0.997
RS1	O15537-1.2	E215M	Pathogenic	0.992
RS1	O15537-1.2	E215N	Pathogenic	0.991
RS1	O15537-1.2	E215P	Pathogenic	0.983
RS1	O15537-1.2	E215Q	Pathogenic	0.529
RS1	O15537-1.2	E215R	Pathogenic	0.989
RS1	O15537-1.2	E215S	Pathogenic	0.981
RS1	O15537-1.2	E215T	Pathogenic	0.993
RS1	O15537-1.2	E215V	Pathogenic	0.991
RS1	O15537-1.2	E215W	Pathogenic	0.995
RS1	O15537-1.2	E215Y	Pathogenic	0.996
RS1	O15537-1.2	L216A	Pathogenic	0.991
RS1	O15537-1.2	L216C	Pathogenic	0.997
RS1	O15537-1.2	L216D	Pathogenic	1.0
RS1	O15537-1.2	L216E	Pathogenic	0.997
RS1	O15537-1.2	L216F	Pathogenic	0.991
RS1	O15537-1.2	L216G	Pathogenic	1.0
RS1	O15537-1.2	L216H	Pathogenic	0.999
RS1	O15537-1.2	L216I	Pathogenic	0.682
RS1	O15537-1.2	L216K	Pathogenic	0.964
RS1	O15537-1.2	L216M	Pathogenic	0.511
RS1	O15537-1.2	L216N	Pathogenic	0.998
RS1	O15537-1.2	L216P	Pathogenic	1.0
RS1	O15537-1.2	L216Q	Pathogenic	0.992
RS1	O15537-1.2	L216R	Pathogenic	0.969
RS1	O15537-1.2	L216S	Pathogenic	0.997
RS1	O15537-1.2	L216T	Pathogenic	0.985
RS1	O15537-1.2	L216V	Pathogenic	0.897
RS1	O15537-1.2	L216W	Pathogenic	1.0
RS1	O15537-1.2	L216Y	Pathogenic	0.995
RS1	O15537-1.2	L217A	Pathogenic	0.99
RS1	O15537-1.2	L217C	Pathogenic	0.996
RS1	O15537-1.2	L217D	Pathogenic	1.0
RS1	O15537-1.2	L217E	Pathogenic	0.997
RS1	O15537-1.2	L217F	Pathogenic	0.99
RS1	O15537-1.2	L217G	Pathogenic	1.0
RS1	O15537-1.2	L217H	Pathogenic	0.999
RS1	O15537-1.2	L217I	Pathogenic	0.654
RS1	O15537-1.2	L217K	Pathogenic	0.959
RS1	O15537-1.2	L217M	Neutral	0.479
RS1	O15537-1.2	L217N	Pathogenic	0.998
RS1	O15537-1.2	L217P	Pathogenic	1.0
RS1	O15537-1.2	L217Q	Pathogenic	0.991
RS1	O15537-1.2	L217R	Pathogenic	0.965
RS1	O15537-1.2	L217S	Pathogenic	0.996
RS1	O15537-1.2	L217T	Pathogenic	0.983
RS1	O15537-1.2	L217V	Pathogenic	0.885
RS1	O15537-1.2	L217W	Pathogenic	1.0
RS1	O15537-1.2	L217Y	Pathogenic	0.995
RS1	O15537-1.2	E218A	Neutral	0.017
RS1	O15537-1.2	E218C	Neutral	0.481
RS1	O15537-1.2	E218D	Neutral	0.0
RS1	O15537-1.2	E218F	Neutral	0.03
RS1	O15537-1.2	E218G	Neutral	0.216
RS1	O15537-1.2	E218H	Neutral	0.002
RS1	O15537-1.2	E218I	Neutral	0.025
RS1	O15537-1.2	E218K	Neutral	0.001
RS1	O15537-1.2	E218L	Neutral	0.03
RS1	O15537-1.2	E218M	Neutral	0.012
RS1	O15537-1.2	E218N	Neutral	0.01
RS1	O15537-1.2	E218P	Neutral	0.005
RS1	O15537-1.2	E218Q	Neutral	0.0
RS1	O15537-1.2	E218R	Neutral	0.008
RS1	O15537-1.2	E218S	Neutral	0.005
RS1	O15537-1.2	E218T	Neutral	0.013
RS1	O15537-1.2	E218V	Neutral	0.01
RS1	O15537-1.2	E218W	Neutral	0.019
RS1	O15537-1.2	E218Y	Neutral	0.026
RS1	O15537-1.2	C219A	Pathogenic	1.0
RS1	O15537-1.2	C219D	Pathogenic	1.0
RS1	O15537-1.2	C219E	Pathogenic	1.0
RS1	O15537-1.2	C219F	Pathogenic	1.0
RS1	O15537-1.2	C219G	Pathogenic	1.0
RS1	O15537-1.2	C219H	Pathogenic	1.0
RS1	O15537-1.2	C219I	Pathogenic	1.0
RS1	O15537-1.2	C219K	Pathogenic	1.0
RS1	O15537-1.2	C219L	Pathogenic	1.0
RS1	O15537-1.2	C219M	Pathogenic	1.0
RS1	O15537-1.2	C219N	Pathogenic	1.0
RS1	O15537-1.2	C219P	Pathogenic	1.0
RS1	O15537-1.2	C219Q	Pathogenic	1.0
RS1	O15537-1.2	C219R	Pathogenic	1.0
RS1	O15537-1.2	C219S	Pathogenic	1.0
RS1	O15537-1.2	C219T	Pathogenic	1.0
RS1	O15537-1.2	C219V	Pathogenic	1.0
RS1	O15537-1.2	C219W	Pathogenic	1.0
RS1	O15537-1.2	C219Y	Pathogenic	1.0
RS1	O15537-1.2	V220A	Neutral	0.0
RS1	O15537-1.2	V220C	Neutral	0.006
RS1	O15537-1.2	V220D	Neutral	0.007
RS1	O15537-1.2	V220E	Neutral	0.001
RS1	O15537-1.2	V220F	Neutral	0.004
RS1	O15537-1.2	V220G	Neutral	0.059
RS1	O15537-1.2	V220H	Neutral	0.04
RS1	O15537-1.2	V220I	Neutral	0.0
RS1	O15537-1.2	V220K	Neutral	0.001
RS1	O15537-1.2	V220L	Neutral	0.0
RS1	O15537-1.2	V220M	Neutral	0.0
RS1	O15537-1.2	V220N	Neutral	0.009
RS1	O15537-1.2	V220P	Neutral	0.021
RS1	O15537-1.2	V220Q	Neutral	0.003
RS1	O15537-1.2	V220R	Neutral	0.007
RS1	O15537-1.2	V220S	Neutral	0.006
RS1	O15537-1.2	V220T	Neutral	0.0
RS1	O15537-1.2	V220W	Neutral	0.084
RS1	O15537-1.2	V220Y	Neutral	0.007
RS1	O15537-1.2	S221A	Neutral	0.0
RS1	O15537-1.2	S221C	Neutral	0.004
RS1	O15537-1.2	S221D	Neutral	0.001
RS1	O15537-1.2	S221E	Neutral	0.002
RS1	O15537-1.2	S221F	Neutral	0.012
RS1	O15537-1.2	S221G	Neutral	0.006
RS1	O15537-1.2	S221H	Neutral	0.036
RS1	O15537-1.2	S221I	Neutral	0.01
RS1	O15537-1.2	S221K	Neutral	0.002
RS1	O15537-1.2	S221L	Neutral	0.012
RS1	O15537-1.2	S221M	Neutral	0.005
RS1	O15537-1.2	S221N	Neutral	0.0
RS1	O15537-1.2	S221P	Neutral	0.008
RS1	O15537-1.2	S221Q	Neutral	0.005
RS1	O15537-1.2	S221R	Neutral	0.012
RS1	O15537-1.2	S221T	Neutral	0.0
RS1	O15537-1.2	S221V	Neutral	0.023
RS1	O15537-1.2	S221W	Neutral	0.045
RS1	O15537-1.2	S221Y	Neutral	0.062
RS1	O15537-1.2	K222A	Pathogenic	0.985
RS1	O15537-1.2	K222C	Pathogenic	0.998
RS1	O15537-1.2	K222D	Pathogenic	0.997
RS1	O15537-1.2	K222E	Pathogenic	0.845
RS1	O15537-1.2	K222F	Pathogenic	0.981
RS1	O15537-1.2	K222G	Pathogenic	0.999
RS1	O15537-1.2	K222H	Pathogenic	0.977
RS1	O15537-1.2	K222I	Pathogenic	0.984
RS1	O15537-1.2	K222L	Pathogenic	0.921
RS1	O15537-1.2	K222M	Pathogenic	0.819
RS1	O15537-1.2	K222N	Pathogenic	0.975
RS1	O15537-1.2	K222P	Pathogenic	0.954
RS1	O15537-1.2	K222Q	Pathogenic	0.689
RS1	O15537-1.2	K222R	Pathogenic	0.575
RS1	O15537-1.2	K222S	Pathogenic	0.949
RS1	O15537-1.2	K222T	Pathogenic	0.98
RS1	O15537-1.2	K222V	Pathogenic	0.976
RS1	O15537-1.2	K222W	Pathogenic	0.97
RS1	O15537-1.2	K222Y	Pathogenic	0.979
RS1	O15537-1.2	C223A	Pathogenic	1.0
RS1	O15537-1.2	C223D	Pathogenic	1.0
RS1	O15537-1.2	C223E	Pathogenic	1.0
RS1	O15537-1.2	C223F	Pathogenic	1.0
RS1	O15537-1.2	C223G	Pathogenic	1.0
RS1	O15537-1.2	C223H	Pathogenic	1.0
RS1	O15537-1.2	C223I	Pathogenic	1.0
RS1	O15537-1.2	C223K	Pathogenic	1.0
RS1	O15537-1.2	C223L	Pathogenic	1.0
RS1	O15537-1.2	C223M	Pathogenic	1.0
RS1	O15537-1.2	C223N	Pathogenic	1.0
RS1	O15537-1.2	C223P	Pathogenic	1.0
RS1	O15537-1.2	C223Q	Pathogenic	1.0
RS1	O15537-1.2	C223R	Pathogenic	1.0
RS1	O15537-1.2	C223S	Pathogenic	1.0
RS1	O15537-1.2	C223T	Pathogenic	1.0
RS1	O15537-1.2	C223V	Pathogenic	1.0
RS1	O15537-1.2	C223W	Pathogenic	1.0
RS1	O15537-1.2	C223Y	Pathogenic	1.0
RS1	O15537-1.2	A224C	Neutral	0.0
RS1	O15537-1.2	A224D	Neutral	0.0
RS1	O15537-1.2	A224E	Neutral	0.0
RS1	O15537-1.2	A224F	Neutral	0.0
RS1	O15537-1.2	A224G	Neutral	0.0
RS1	O15537-1.2	A224H	Neutral	0.0
RS1	O15537-1.2	A224I	Neutral	0.0
RS1	O15537-1.2	A224K	Neutral	0.0
RS1	O15537-1.2	A224L	Neutral	0.0
RS1	O15537-1.2	A224M	Neutral	0.0
RS1	O15537-1.2	A224N	Neutral	0.0
RS1	O15537-1.2	A224P	Neutral	0.0
RS1	O15537-1.2	A224Q	Neutral	0.0
RS1	O15537-1.2	A224R	Neutral	0.0
RS1	O15537-1.2	A224S	Neutral	0.0
RS1	O15537-1.2	A224T	Neutral	0.0
RS1	O15537-1.2	A224V	Neutral	0.0
RS1	O15537-1.2	A224W	Neutral	0.0
RS1	O15537-1.2	A224Y	Neutral	0.0
SLC26A4	O43511-1.1	M1A	Pathogenic	0.851
SLC26A4	O43511-1.1	M1C	Pathogenic	0.946
SLC26A4	O43511-1.1	M1D	Pathogenic	0.978
SLC26A4	O43511-1.1	M1E	Pathogenic	0.981
SLC26A4	O43511-1.1	M1F	Pathogenic	0.963
SLC26A4	O43511-1.1	M1G	Pathogenic	0.897
SLC26A4	O43511-1.1	M1H	Pathogenic	0.991
SLC26A4	O43511-1.1	M1I	Pathogenic	0.955
SLC26A4	O43511-1.1	M1K	Pathogenic	0.965
SLC26A4	O43511-1.1	M1L	Pathogenic	0.917
SLC26A4	O43511-1.1	M1N	Pathogenic	0.968
SLC26A4	O43511-1.1	M1P	Pathogenic	0.974
SLC26A4	O43511-1.1	M1Q	Pathogenic	0.951
SLC26A4	O43511-1.1	M1R	Pathogenic	0.938
SLC26A4	O43511-1.1	M1S	Pathogenic	0.868
SLC26A4	O43511-1.1	M1T	Pathogenic	0.948
SLC26A4	O43511-1.1	M1V	Pathogenic	0.918
SLC26A4	O43511-1.1	M1W	Pathogenic	0.925
SLC26A4	O43511-1.1	M1Y	Pathogenic	0.978
SLC26A4	O43511-1.1	A2C	Neutral	0.01
SLC26A4	O43511-1.1	A2D	Neutral	0.028
SLC26A4	O43511-1.1	A2E	Neutral	0.007
SLC26A4	O43511-1.1	A2F	Neutral	0.003
SLC26A4	O43511-1.1	A2G	Neutral	0.012
SLC26A4	O43511-1.1	A2H	Neutral	0.012
SLC26A4	O43511-1.1	A2I	Neutral	0.003
SLC26A4	O43511-1.1	A2K	Neutral	0.002
SLC26A4	O43511-1.1	A2L	Neutral	0.003
SLC26A4	O43511-1.1	A2M	Neutral	0.003
SLC26A4	O43511-1.1	A2N	Neutral	0.024
SLC26A4	O43511-1.1	A2P	Neutral	0.019
SLC26A4	O43511-1.1	A2Q	Neutral	0.006
SLC26A4	O43511-1.1	A2R	Neutral	0.001
SLC26A4	O43511-1.1	A2S	Neutral	0.011
SLC26A4	O43511-1.1	A2T	Neutral	0.01
SLC26A4	O43511-1.1	A2V	Neutral	0.004
SLC26A4	O43511-1.1	A2W	Neutral	0.002
SLC26A4	O43511-1.1	A2Y	Neutral	0.004
SLC26A4	O43511-1.1	A3C	Neutral	0.074
SLC26A4	O43511-1.1	A3D	Neutral	0.181
SLC26A4	O43511-1.1	A3E	Neutral	0.049
SLC26A4	O43511-1.1	A3F	Neutral	0.025
SLC26A4	O43511-1.1	A3G	Neutral	0.085
SLC26A4	O43511-1.1	A3H	Neutral	0.085
SLC26A4	O43511-1.1	A3I	Neutral	0.021
SLC26A4	O43511-1.1	A3K	Neutral	0.014
SLC26A4	O43511-1.1	A3L	Neutral	0.022
SLC26A4	O43511-1.1	A3M	Neutral	0.026
SLC26A4	O43511-1.1	A3N	Neutral	0.159
SLC26A4	O43511-1.1	A3P	Neutral	0.13
SLC26A4	O43511-1.1	A3Q	Neutral	0.046
SLC26A4	O43511-1.1	A3R	Neutral	0.008
SLC26A4	O43511-1.1	A3S	Neutral	0.076
SLC26A4	O43511-1.1	A3T	Neutral	0.069
SLC26A4	O43511-1.1	A3V	Neutral	0.03
SLC26A4	O43511-1.1	A3W	Neutral	0.012
SLC26A4	O43511-1.1	A3Y	Neutral	0.027
SLC26A4	O43511-1.1	P4A	Pathogenic	0.703
SLC26A4	O43511-1.1	P4C	Pathogenic	0.96
SLC26A4	O43511-1.1	P4D	Pathogenic	0.809
SLC26A4	O43511-1.1	P4E	Pathogenic	0.664
SLC26A4	O43511-1.1	P4F	Pathogenic	0.847
SLC26A4	O43511-1.1	P4G	Pathogenic	0.642
SLC26A4	O43511-1.1	P4H	Pathogenic	0.78
SLC26A4	O43511-1.1	P4I	Pathogenic	0.818
SLC26A4	O43511-1.1	P4K	Neutral	0.348
SLC26A4	O43511-1.1	P4L	Pathogenic	0.824
SLC26A4	O43511-1.1	P4M	Pathogenic	0.736
SLC26A4	O43511-1.1	P4N	Pathogenic	0.878
SLC26A4	O43511-1.1	P4Q	Pathogenic	0.649
SLC26A4	O43511-1.1	P4R	Neutral	0.372
SLC26A4	O43511-1.1	P4S	Pathogenic	0.731
SLC26A4	O43511-1.1	P4T	Pathogenic	0.851
SLC26A4	O43511-1.1	P4V	Pathogenic	0.869
SLC26A4	O43511-1.1	P4W	Pathogenic	0.566
SLC26A4	O43511-1.1	P4Y	Pathogenic	0.743
SLC26A4	O43511-1.1	G5A	Neutral	0.063
SLC26A4	O43511-1.1	G5C	Neutral	0.152
SLC26A4	O43511-1.1	G5D	Neutral	0.037
SLC26A4	O43511-1.1	G5E	Neutral	0.035
SLC26A4	O43511-1.1	G5F	Neutral	0.014
SLC26A4	O43511-1.1	G5H	Neutral	0.028
SLC26A4	O43511-1.1	G5I	Neutral	0.045
SLC26A4	O43511-1.1	G5K	Neutral	0.01
SLC26A4	O43511-1.1	G5L	Neutral	0.047
SLC26A4	O43511-1.1	G5M	Neutral	0.028
SLC26A4	O43511-1.1	G5N	Neutral	0.016
SLC26A4	O43511-1.1	G5P	Neutral	0.076
SLC26A4	O43511-1.1	G5Q	Neutral	0.033
SLC26A4	O43511-1.1	G5R	Neutral	0.005
SLC26A4	O43511-1.1	G5S	Neutral	0.054
SLC26A4	O43511-1.1	G5T	Neutral	0.079
SLC26A4	O43511-1.1	G5V	Neutral	0.065
SLC26A4	O43511-1.1	G5W	Neutral	0.002
SLC26A4	O43511-1.1	G5Y	Neutral	0.015
SLC26A4	O43511-1.1	G6A	Neutral	0.277
SLC26A4	O43511-1.1	G6C	Pathogenic	0.505
SLC26A4	O43511-1.1	G6D	Neutral	0.179
SLC26A4	O43511-1.1	G6E	Neutral	0.17
SLC26A4	O43511-1.1	G6F	Neutral	0.076
SLC26A4	O43511-1.1	G6H	Neutral	0.142
SLC26A4	O43511-1.1	G6I	Neutral	0.211
SLC26A4	O43511-1.1	G6K	Neutral	0.052
SLC26A4	O43511-1.1	G6L	Neutral	0.218
SLC26A4	O43511-1.1	G6M	Neutral	0.143
SLC26A4	O43511-1.1	G6N	Neutral	0.085
SLC26A4	O43511-1.1	G6P	Neutral	0.319
SLC26A4	O43511-1.1	G6Q	Neutral	0.161
SLC26A4	O43511-1.1	G6R	Neutral	0.03
SLC26A4	O43511-1.1	G6S	Neutral	0.245
SLC26A4	O43511-1.1	G6T	Neutral	0.328
SLC26A4	O43511-1.1	G6V	Neutral	0.283
SLC26A4	O43511-1.1	G6W	Neutral	0.01
SLC26A4	O43511-1.1	G6Y	Neutral	0.079
SLC26A4	O43511-1.1	R7A	Neutral	0.013
SLC26A4	O43511-1.1	R7C	Neutral	0.086
SLC26A4	O43511-1.1	R7D	Neutral	0.104
SLC26A4	O43511-1.1	R7E	Neutral	0.058
SLC26A4	O43511-1.1	R7F	Neutral	0.387
SLC26A4	O43511-1.1	R7G	Neutral	0.012
SLC26A4	O43511-1.1	R7H	Neutral	0.064
SLC26A4	O43511-1.1	R7I	Neutral	0.277
SLC26A4	O43511-1.1	R7K	Neutral	0.053
SLC26A4	O43511-1.1	R7L	Neutral	0.165
SLC26A4	O43511-1.1	R7M	Neutral	0.106
SLC26A4	O43511-1.1	R7N	Neutral	0.033
SLC26A4	O43511-1.1	R7P	Neutral	0.059
SLC26A4	O43511-1.1	R7Q	Neutral	0.032
SLC26A4	O43511-1.1	R7S	Neutral	0.019
SLC26A4	O43511-1.1	R7T	Neutral	0.041
SLC26A4	O43511-1.1	R7V	Neutral	0.169
SLC26A4	O43511-1.1	R7W	Neutral	0.326
SLC26A4	O43511-1.1	R7Y	Neutral	0.362
SLC26A4	O43511-1.1	S8A	Neutral	0.011
SLC26A4	O43511-1.1	S8C	Neutral	0.025
SLC26A4	O43511-1.1	S8D	Neutral	0.011
SLC26A4	O43511-1.1	S8E	Neutral	0.005
SLC26A4	O43511-1.1	S8F	Neutral	0.004
SLC26A4	O43511-1.1	S8G	Neutral	0.011
SLC26A4	O43511-1.1	S8H	Neutral	0.008
SLC26A4	O43511-1.1	S8I	Neutral	0.007
SLC26A4	O43511-1.1	S8K	Neutral	0.001
SLC26A4	O43511-1.1	S8L	Neutral	0.007
SLC26A4	O43511-1.1	S8M	Neutral	0.004
SLC26A4	O43511-1.1	S8N	Neutral	0.005
SLC26A4	O43511-1.1	S8P	Neutral	0.023
SLC26A4	O43511-1.1	S8Q	Neutral	0.005
SLC26A4	O43511-1.1	S8R	Neutral	0.002
SLC26A4	O43511-1.1	S8T	Neutral	0.006
SLC26A4	O43511-1.1	S8V	Neutral	0.02
SLC26A4	O43511-1.1	S8W	Neutral	0.002
SLC26A4	O43511-1.1	S8Y	Neutral	0.004
SLC26A4	O43511-1.1	E9A	Neutral	0.446
SLC26A4	O43511-1.1	E9C	Pathogenic	0.922
SLC26A4	O43511-1.1	E9D	Neutral	0.287
SLC26A4	O43511-1.1	E9F	Pathogenic	0.791
SLC26A4	O43511-1.1	E9G	Neutral	0.436
SLC26A4	O43511-1.1	E9H	Pathogenic	0.656
SLC26A4	O43511-1.1	E9I	Pathogenic	0.861
SLC26A4	O43511-1.1	E9K	Neutral	0.341
SLC26A4	O43511-1.1	E9L	Pathogenic	0.866
SLC26A4	O43511-1.1	E9M	Pathogenic	0.793
SLC26A4	O43511-1.1	E9N	Pathogenic	0.678
SLC26A4	O43511-1.1	E9P	Pathogenic	0.66
SLC26A4	O43511-1.1	E9Q	Neutral	0.393
SLC26A4	O43511-1.1	E9R	Neutral	0.365
SLC26A4	O43511-1.1	E9S	Neutral	0.375
SLC26A4	O43511-1.1	E9T	Pathogenic	0.727
SLC26A4	O43511-1.1	E9V	Pathogenic	0.864
SLC26A4	O43511-1.1	E9W	Neutral	0.472
SLC26A4	O43511-1.1	E9Y	Pathogenic	0.664
SLC26A4	O43511-1.1	P10A	Pathogenic	0.672
SLC26A4	O43511-1.1	P10C	Pathogenic	0.954
SLC26A4	O43511-1.1	P10D	Pathogenic	0.785
SLC26A4	O43511-1.1	P10E	Pathogenic	0.631
SLC26A4	O43511-1.1	P10F	Pathogenic	0.827
SLC26A4	O43511-1.1	P10G	Pathogenic	0.608
SLC26A4	O43511-1.1	P10H	Pathogenic	0.755
SLC26A4	O43511-1.1	P10I	Pathogenic	0.795
SLC26A4	O43511-1.1	P10K	Neutral	0.316
SLC26A4	O43511-1.1	P10L	Pathogenic	0.802
SLC26A4	O43511-1.1	P10M	Pathogenic	0.707
SLC26A4	O43511-1.1	P10N	Pathogenic	0.862
SLC26A4	O43511-1.1	P10Q	Pathogenic	0.616
SLC26A4	O43511-1.1	P10R	Neutral	0.339
SLC26A4	O43511-1.1	P10S	Pathogenic	0.702
SLC26A4	O43511-1.1	P10T	Pathogenic	0.832
SLC26A4	O43511-1.1	P10V	Pathogenic	0.851
SLC26A4	O43511-1.1	P10W	Pathogenic	0.531
SLC26A4	O43511-1.1	P10Y	Pathogenic	0.714
SLC26A4	O43511-1.1	P11A	Pathogenic	0.567
SLC26A4	O43511-1.1	P11C	Pathogenic	0.929
SLC26A4	O43511-1.1	P11D	Pathogenic	0.7
SLC26A4	O43511-1.1	P11E	Pathogenic	0.521
SLC26A4	O43511-1.1	P11F	Pathogenic	0.753
SLC26A4	O43511-1.1	P11G	Neutral	0.497
SLC26A4	O43511-1.1	P11H	Pathogenic	0.662
SLC26A4	O43511-1.1	P11I	Pathogenic	0.712
SLC26A4	O43511-1.1	P11K	Neutral	0.227
SLC26A4	O43511-1.1	P11L	Pathogenic	0.72
SLC26A4	O43511-1.1	P11M	Pathogenic	0.606
SLC26A4	O43511-1.1	P11N	Pathogenic	0.799
SLC26A4	O43511-1.1	P11Q	Pathogenic	0.505
SLC26A4	O43511-1.1	P11R	Neutral	0.246
SLC26A4	O43511-1.1	P11S	Pathogenic	0.6
SLC26A4	O43511-1.1	P11T	Pathogenic	0.76
SLC26A4	O43511-1.1	P11V	Pathogenic	0.785
SLC26A4	O43511-1.1	P11W	Neutral	0.419
SLC26A4	O43511-1.1	P11Y	Pathogenic	0.614
SLC26A4	O43511-1.1	Q12A	Neutral	0.189
SLC26A4	O43511-1.1	Q12C	Pathogenic	0.631
SLC26A4	O43511-1.1	Q12D	Neutral	0.253
SLC26A4	O43511-1.1	Q12E	Neutral	0.166
SLC26A4	O43511-1.1	Q12F	Pathogenic	0.632
SLC26A4	O43511-1.1	Q12G	Neutral	0.183
SLC26A4	O43511-1.1	Q12H	Neutral	0.464
SLC26A4	O43511-1.1	Q12I	Pathogenic	0.737
SLC26A4	O43511-1.1	Q12K	Neutral	0.145
SLC26A4	O43511-1.1	Q12L	Pathogenic	0.592
SLC26A4	O43511-1.1	Q12M	Neutral	0.301
SLC26A4	O43511-1.1	Q12N	Neutral	0.312
SLC26A4	O43511-1.1	Q12P	Neutral	0.36
SLC26A4	O43511-1.1	Q12R	Neutral	0.086
SLC26A4	O43511-1.1	Q12S	Neutral	0.148
SLC26A4	O43511-1.1	Q12T	Neutral	0.434
SLC26A4	O43511-1.1	Q12V	Pathogenic	0.647
SLC26A4	O43511-1.1	Q12W	Neutral	0.168
SLC26A4	O43511-1.1	Q12Y	Neutral	0.309
SLC26A4	O43511-1.1	L13A	Neutral	0.054
SLC26A4	O43511-1.1	L13C	Neutral	0.148
SLC26A4	O43511-1.1	L13D	Neutral	0.473
SLC26A4	O43511-1.1	L13E	Pathogenic	0.515
SLC26A4	O43511-1.1	L13F	Neutral	0.272
SLC26A4	O43511-1.1	L13G	Neutral	0.148
SLC26A4	O43511-1.1	L13H	Pathogenic	0.682
SLC26A4	O43511-1.1	L13I	Neutral	0.131
SLC26A4	O43511-1.1	L13K	Neutral	0.356
SLC26A4	O43511-1.1	L13M	Neutral	0.116
SLC26A4	O43511-1.1	L13N	Neutral	0.374
SLC26A4	O43511-1.1	L13P	Neutral	0.431
SLC26A4	O43511-1.1	L13Q	Neutral	0.437
SLC26A4	O43511-1.1	L13R	Neutral	0.234
SLC26A4	O43511-1.1	L13S	Neutral	0.116
SLC26A4	O43511-1.1	L13T	Neutral	0.153
SLC26A4	O43511-1.1	L13V	Neutral	0.1
SLC26A4	O43511-1.1	L13W	Neutral	0.263
SLC26A4	O43511-1.1	L13Y	Neutral	0.308
SLC26A4	O43511-1.1	P14A	Neutral	0.34
SLC26A4	O43511-1.1	P14C	Pathogenic	0.838
SLC26A4	O43511-1.1	P14D	Neutral	0.478
SLC26A4	O43511-1.1	P14E	Neutral	0.3
SLC26A4	O43511-1.1	P14F	Pathogenic	0.545
SLC26A4	O43511-1.1	P14G	Neutral	0.28
SLC26A4	O43511-1.1	P14H	Neutral	0.435
SLC26A4	O43511-1.1	P14I	Neutral	0.494
SLC26A4	O43511-1.1	P14K	Neutral	0.104
SLC26A4	O43511-1.1	P14L	Pathogenic	0.504
SLC26A4	O43511-1.1	P14M	Neutral	0.377
SLC26A4	O43511-1.1	P14N	Pathogenic	0.611
SLC26A4	O43511-1.1	P14Q	Neutral	0.286
SLC26A4	O43511-1.1	P14R	Neutral	0.114
SLC26A4	O43511-1.1	P14S	Neutral	0.371
SLC26A4	O43511-1.1	P14T	Pathogenic	0.555
SLC26A4	O43511-1.1	P14V	Pathogenic	0.589
SLC26A4	O43511-1.1	P14W	Neutral	0.221
SLC26A4	O43511-1.1	P14Y	Neutral	0.385
SLC26A4	O43511-1.1	E15A	Neutral	0.154
SLC26A4	O43511-1.1	E15C	Pathogenic	0.728
SLC26A4	O43511-1.1	E15D	Neutral	0.083
SLC26A4	O43511-1.1	E15F	Neutral	0.46
SLC26A4	O43511-1.1	E15G	Neutral	0.148
SLC26A4	O43511-1.1	E15H	Neutral	0.3
SLC26A4	O43511-1.1	E15I	Pathogenic	0.582
SLC26A4	O43511-1.1	E15K	Neutral	0.104
SLC26A4	O43511-1.1	E15L	Pathogenic	0.591
SLC26A4	O43511-1.1	E15M	Neutral	0.463
SLC26A4	O43511-1.1	E15N	Neutral	0.322
SLC26A4	O43511-1.1	E15P	Neutral	0.304
SLC26A4	O43511-1.1	E15Q	Neutral	0.127
SLC26A4	O43511-1.1	E15R	Neutral	0.114
SLC26A4	O43511-1.1	E15S	Neutral	0.119
SLC26A4	O43511-1.1	E15T	Neutral	0.374
SLC26A4	O43511-1.1	E15V	Pathogenic	0.588
SLC26A4	O43511-1.1	E15W	Neutral	0.168
SLC26A4	O43511-1.1	E15Y	Neutral	0.308
SLC26A4	O43511-1.1	Y16A	Neutral	0.117
SLC26A4	O43511-1.1	Y16C	Neutral	0.285
SLC26A4	O43511-1.1	Y16D	Neutral	0.342
SLC26A4	O43511-1.1	Y16E	Neutral	0.381
SLC26A4	O43511-1.1	Y16F	Neutral	0.076
SLC26A4	O43511-1.1	Y16G	Neutral	0.091
SLC26A4	O43511-1.1	Y16H	Neutral	0.071
SLC26A4	O43511-1.1	Y16I	Neutral	0.446
SLC26A4	O43511-1.1	Y16K	Pathogenic	0.634
SLC26A4	O43511-1.1	Y16L	Neutral	0.456
SLC26A4	O43511-1.1	Y16M	Pathogenic	0.501
SLC26A4	O43511-1.1	Y16N	Neutral	0.257
SLC26A4	O43511-1.1	Y16P	Neutral	0.469
SLC26A4	O43511-1.1	Y16Q	Neutral	0.311
SLC26A4	O43511-1.1	Y16R	Pathogenic	0.623
SLC26A4	O43511-1.1	Y16S	Neutral	0.132
SLC26A4	O43511-1.1	Y16T	Neutral	0.296
SLC26A4	O43511-1.1	Y16V	Neutral	0.3
SLC26A4	O43511-1.1	Y16W	Neutral	0.063
SLC26A4	O43511-1.1	S17A	Neutral	0.115
SLC26A4	O43511-1.1	S17C	Neutral	0.228
SLC26A4	O43511-1.1	S17D	Neutral	0.116
SLC26A4	O43511-1.1	S17E	Neutral	0.058
SLC26A4	O43511-1.1	S17F	Neutral	0.045
SLC26A4	O43511-1.1	S17G	Neutral	0.111
SLC26A4	O43511-1.1	S17H	Neutral	0.088
SLC26A4	O43511-1.1	S17I	Neutral	0.072
SLC26A4	O43511-1.1	S17K	Neutral	0.016
SLC26A4	O43511-1.1	S17L	Neutral	0.075
SLC26A4	O43511-1.1	S17M	Neutral	0.046
SLC26A4	O43511-1.1	S17N	Neutral	0.053
SLC26A4	O43511-1.1	S17P	Neutral	0.215
SLC26A4	O43511-1.1	S17Q	Neutral	0.054
SLC26A4	O43511-1.1	S17R	Neutral	0.018
SLC26A4	O43511-1.1	S17T	Neutral	0.066
SLC26A4	O43511-1.1	S17V	Neutral	0.187
SLC26A4	O43511-1.1	S17W	Neutral	0.022
SLC26A4	O43511-1.1	S17Y	Neutral	0.048
SLC26A4	O43511-1.1	C18A	Pathogenic	0.63
SLC26A4	O43511-1.1	C18D	Pathogenic	0.945
SLC26A4	O43511-1.1	C18E	Pathogenic	0.942
SLC26A4	O43511-1.1	C18F	Pathogenic	0.628
SLC26A4	O43511-1.1	C18G	Pathogenic	0.839
SLC26A4	O43511-1.1	C18H	Pathogenic	0.878
SLC26A4	O43511-1.1	C18I	Pathogenic	0.579
SLC26A4	O43511-1.1	C18K	Pathogenic	0.684
SLC26A4	O43511-1.1	C18L	Pathogenic	0.588
SLC26A4	O43511-1.1	C18M	Pathogenic	0.631
SLC26A4	O43511-1.1	C18N	Pathogenic	0.936
SLC26A4	O43511-1.1	C18P	Pathogenic	0.97
SLC26A4	O43511-1.1	C18Q	Pathogenic	0.883
SLC26A4	O43511-1.1	C18R	Pathogenic	0.545
SLC26A4	O43511-1.1	C18S	Pathogenic	0.797
SLC26A4	O43511-1.1	C18T	Pathogenic	0.852
SLC26A4	O43511-1.1	C18V	Pathogenic	0.802
SLC26A4	O43511-1.1	C18W	Neutral	0.285
SLC26A4	O43511-1.1	C18Y	Pathogenic	0.635
SLC26A4	O43511-1.1	S19A	Neutral	0.103
SLC26A4	O43511-1.1	S19C	Neutral	0.207
SLC26A4	O43511-1.1	S19D	Neutral	0.103
SLC26A4	O43511-1.1	S19E	Neutral	0.051
SLC26A4	O43511-1.1	S19F	Neutral	0.04
SLC26A4	O43511-1.1	S19G	Neutral	0.099
SLC26A4	O43511-1.1	S19H	Neutral	0.079
SLC26A4	O43511-1.1	S19I	Neutral	0.064
SLC26A4	O43511-1.1	S19K	Neutral	0.014
SLC26A4	O43511-1.1	S19L	Neutral	0.067
SLC26A4	O43511-1.1	S19M	Neutral	0.041
SLC26A4	O43511-1.1	S19N	Neutral	0.047
SLC26A4	O43511-1.1	S19P	Neutral	0.194
SLC26A4	O43511-1.1	S19Q	Neutral	0.048
SLC26A4	O43511-1.1	S19R	Neutral	0.016
SLC26A4	O43511-1.1	S19T	Neutral	0.059
SLC26A4	O43511-1.1	S19V	Neutral	0.168
SLC26A4	O43511-1.1	S19W	Neutral	0.02
SLC26A4	O43511-1.1	S19Y	Neutral	0.042
SLC26A4	O43511-1.1	Y20A	Pathogenic	0.901
SLC26A4	O43511-1.1	Y20C	Pathogenic	0.965
SLC26A4	O43511-1.1	Y20D	Pathogenic	0.973
SLC26A4	O43511-1.1	Y20E	Pathogenic	0.977
SLC26A4	O43511-1.1	Y20F	Pathogenic	0.849
SLC26A4	O43511-1.1	Y20G	Pathogenic	0.874
SLC26A4	O43511-1.1	Y20H	Pathogenic	0.84
SLC26A4	O43511-1.1	Y20I	Pathogenic	0.982
SLC26A4	O43511-1.1	Y20K	Pathogenic	0.992
SLC26A4	O43511-1.1	Y20L	Pathogenic	0.983
SLC26A4	O43511-1.1	Y20M	Pathogenic	0.986
SLC26A4	O43511-1.1	Y20N	Pathogenic	0.96
SLC26A4	O43511-1.1	Y20P	Pathogenic	0.984
SLC26A4	O43511-1.1	Y20Q	Pathogenic	0.969
SLC26A4	O43511-1.1	Y20R	Pathogenic	0.991
SLC26A4	O43511-1.1	Y20S	Pathogenic	0.913
SLC26A4	O43511-1.1	Y20T	Pathogenic	0.967
SLC26A4	O43511-1.1	Y20V	Pathogenic	0.967
SLC26A4	O43511-1.1	Y20W	Pathogenic	0.821
SLC26A4	O43511-1.1	M21A	Neutral	0.0
SLC26A4	O43511-1.1	M21C	Neutral	0.001
SLC26A4	O43511-1.1	M21D	Neutral	0.003
SLC26A4	O43511-1.1	M21E	Neutral	0.004
SLC26A4	O43511-1.1	M21F	Neutral	0.002
SLC26A4	O43511-1.1	M21G	Neutral	0.001
SLC26A4	O43511-1.1	M21H	Neutral	0.008
SLC26A4	O43511-1.1	M21I	Neutral	0.002
SLC26A4	O43511-1.1	M21K	Neutral	0.002
SLC26A4	O43511-1.1	M21L	Neutral	0.001
SLC26A4	O43511-1.1	M21N	Neutral	0.002
SLC26A4	O43511-1.1	M21P	Neutral	0.003
SLC26A4	O43511-1.1	M21Q	Neutral	0.001
SLC26A4	O43511-1.1	M21R	Neutral	0.001
SLC26A4	O43511-1.1	M21S	Neutral	0.0
SLC26A4	O43511-1.1	M21T	Neutral	0.001
SLC26A4	O43511-1.1	M21V	Neutral	0.001
SLC26A4	O43511-1.1	M21W	Neutral	0.001
SLC26A4	O43511-1.1	M21Y	Neutral	0.003
SLC26A4	O43511-1.1	V22A	Neutral	0.452
SLC26A4	O43511-1.1	V22C	Pathogenic	0.835
SLC26A4	O43511-1.1	V22D	Pathogenic	0.929
SLC26A4	O43511-1.1	V22E	Pathogenic	0.915
SLC26A4	O43511-1.1	V22F	Pathogenic	0.73
SLC26A4	O43511-1.1	V22G	Pathogenic	0.716
SLC26A4	O43511-1.1	V22H	Pathogenic	0.951
SLC26A4	O43511-1.1	V22I	Neutral	0.214
SLC26A4	O43511-1.1	V22K	Pathogenic	0.744
SLC26A4	O43511-1.1	V22L	Pathogenic	0.533
SLC26A4	O43511-1.1	V22M	Pathogenic	0.578
SLC26A4	O43511-1.1	V22N	Pathogenic	0.946
SLC26A4	O43511-1.1	V22P	Pathogenic	0.917
SLC26A4	O43511-1.1	V22Q	Pathogenic	0.91
SLC26A4	O43511-1.1	V22R	Pathogenic	0.763
SLC26A4	O43511-1.1	V22S	Pathogenic	0.793
SLC26A4	O43511-1.1	V22T	Pathogenic	0.723
SLC26A4	O43511-1.1	V22W	Pathogenic	0.721
SLC26A4	O43511-1.1	V22Y	Pathogenic	0.7
SLC26A4	O43511-1.1	S23A	Neutral	0.08
SLC26A4	O43511-1.1	S23C	Neutral	0.166
SLC26A4	O43511-1.1	S23D	Neutral	0.081
SLC26A4	O43511-1.1	S23E	Neutral	0.04
SLC26A4	O43511-1.1	S23F	Neutral	0.031
SLC26A4	O43511-1.1	S23G	Neutral	0.077
SLC26A4	O43511-1.1	S23H	Neutral	0.061
SLC26A4	O43511-1.1	S23I	Neutral	0.05
SLC26A4	O43511-1.1	S23K	Neutral	0.011
SLC26A4	O43511-1.1	S23L	Neutral	0.052
SLC26A4	O43511-1.1	S23M	Neutral	0.031
SLC26A4	O43511-1.1	S23N	Neutral	0.036
SLC26A4	O43511-1.1	S23P	Neutral	0.155
SLC26A4	O43511-1.1	S23Q	Neutral	0.037
SLC26A4	O43511-1.1	S23R	Neutral	0.012
SLC26A4	O43511-1.1	S23T	Neutral	0.045
SLC26A4	O43511-1.1	S23V	Neutral	0.134
SLC26A4	O43511-1.1	S23W	Neutral	0.015
SLC26A4	O43511-1.1	S23Y	Neutral	0.033
SLC26A4	O43511-1.1	R24A	Pathogenic	0.776
SLC26A4	O43511-1.1	R24C	Pathogenic	0.962
SLC26A4	O43511-1.1	R24D	Pathogenic	0.969
SLC26A4	O43511-1.1	R24E	Pathogenic	0.943
SLC26A4	O43511-1.1	R24F	Pathogenic	0.994
SLC26A4	O43511-1.1	R24G	Pathogenic	0.769
SLC26A4	O43511-1.1	R24H	Pathogenic	0.949
SLC26A4	O43511-1.1	R24I	Pathogenic	0.99
SLC26A4	O43511-1.1	R24K	Pathogenic	0.938
SLC26A4	O43511-1.1	R24L	Pathogenic	0.982
SLC26A4	O43511-1.1	R24M	Pathogenic	0.97
SLC26A4	O43511-1.1	R24N	Pathogenic	0.901
SLC26A4	O43511-1.1	R24P	Pathogenic	0.944
SLC26A4	O43511-1.1	R24Q	Pathogenic	0.898
SLC26A4	O43511-1.1	R24S	Pathogenic	0.839
SLC26A4	O43511-1.1	R24T	Pathogenic	0.92
SLC26A4	O43511-1.1	R24V	Pathogenic	0.982
SLC26A4	O43511-1.1	R24W	Pathogenic	0.992
SLC26A4	O43511-1.1	R24Y	Pathogenic	0.994
SLC26A4	O43511-1.1	P25A	Pathogenic	0.976
SLC26A4	O43511-1.1	P25C	Pathogenic	0.998
SLC26A4	O43511-1.1	P25D	Pathogenic	0.986
SLC26A4	O43511-1.1	P25E	Pathogenic	0.971
SLC26A4	O43511-1.1	P25F	Pathogenic	0.99
SLC26A4	O43511-1.1	P25G	Pathogenic	0.969
SLC26A4	O43511-1.1	P25H	Pathogenic	0.984
SLC26A4	O43511-1.1	P25I	Pathogenic	0.987
SLC26A4	O43511-1.1	P25K	Pathogenic	0.902
SLC26A4	O43511-1.1	P25L	Pathogenic	0.988
SLC26A4	O43511-1.1	P25M	Pathogenic	0.98
SLC26A4	O43511-1.1	P25N	Pathogenic	0.992
SLC26A4	O43511-1.1	P25Q	Pathogenic	0.97
SLC26A4	O43511-1.1	P25R	Pathogenic	0.911
SLC26A4	O43511-1.1	P25S	Pathogenic	0.979
SLC26A4	O43511-1.1	P25T	Pathogenic	0.99
SLC26A4	O43511-1.1	P25V	Pathogenic	0.991
SLC26A4	O43511-1.1	P25W	Pathogenic	0.957
SLC26A4	O43511-1.1	P25Y	Pathogenic	0.98
SLC26A4	O43511-1.1	V26A	Neutral	0.248
SLC26A4	O43511-1.1	V26C	Pathogenic	0.67
SLC26A4	O43511-1.1	V26D	Pathogenic	0.839
SLC26A4	O43511-1.1	V26E	Pathogenic	0.811
SLC26A4	O43511-1.1	V26F	Pathogenic	0.52
SLC26A4	O43511-1.1	V26G	Pathogenic	0.502
SLC26A4	O43511-1.1	V26H	Pathogenic	0.886
SLC26A4	O43511-1.1	V26I	Neutral	0.098
SLC26A4	O43511-1.1	V26K	Pathogenic	0.537
SLC26A4	O43511-1.1	V26L	Neutral	0.314
SLC26A4	O43511-1.1	V26M	Neutral	0.354
SLC26A4	O43511-1.1	V26N	Pathogenic	0.875
SLC26A4	O43511-1.1	V26P	Pathogenic	0.815
SLC26A4	O43511-1.1	V26Q	Pathogenic	0.801
SLC26A4	O43511-1.1	V26R	Pathogenic	0.563
SLC26A4	O43511-1.1	V26S	Pathogenic	0.605
SLC26A4	O43511-1.1	V26T	Pathogenic	0.512
SLC26A4	O43511-1.1	V26W	Pathogenic	0.509
SLC26A4	O43511-1.1	V26Y	Neutral	0.483
SLC26A4	O43511-1.1	Y27A	Pathogenic	0.93
SLC26A4	O43511-1.1	Y27C	Pathogenic	0.976
SLC26A4	O43511-1.1	Y27D	Pathogenic	0.981
SLC26A4	O43511-1.1	Y27E	Pathogenic	0.984
SLC26A4	O43511-1.1	Y27F	Pathogenic	0.891
SLC26A4	O43511-1.1	Y27G	Pathogenic	0.91
SLC26A4	O43511-1.1	Y27H	Pathogenic	0.885
SLC26A4	O43511-1.1	Y27I	Pathogenic	0.988
SLC26A4	O43511-1.1	Y27K	Pathogenic	0.994
SLC26A4	O43511-1.1	Y27L	Pathogenic	0.988
SLC26A4	O43511-1.1	Y27M	Pathogenic	0.99
SLC26A4	O43511-1.1	Y27N	Pathogenic	0.972
SLC26A4	O43511-1.1	Y27P	Pathogenic	0.989
SLC26A4	O43511-1.1	Y27Q	Pathogenic	0.978
SLC26A4	O43511-1.1	Y27R	Pathogenic	0.994
SLC26A4	O43511-1.1	Y27S	Pathogenic	0.939
SLC26A4	O43511-1.1	Y27T	Pathogenic	0.977
SLC26A4	O43511-1.1	Y27V	Pathogenic	0.977
SLC26A4	O43511-1.1	Y27W	Pathogenic	0.87
SLC26A4	O43511-1.1	S28A	Pathogenic	0.696
SLC26A4	O43511-1.1	S28C	Pathogenic	0.839
SLC26A4	O43511-1.1	S28D	Pathogenic	0.697
SLC26A4	O43511-1.1	S28E	Pathogenic	0.518
SLC26A4	O43511-1.1	S28F	Neutral	0.456
SLC26A4	O43511-1.1	S28G	Pathogenic	0.687
SLC26A4	O43511-1.1	S28H	Pathogenic	0.63
SLC26A4	O43511-1.1	S28I	Pathogenic	0.578
SLC26A4	O43511-1.1	S28K	Neutral	0.225
SLC26A4	O43511-1.1	S28L	Pathogenic	0.587
SLC26A4	O43511-1.1	S28M	Neutral	0.459
SLC26A4	O43511-1.1	S28N	Neutral	0.494
SLC26A4	O43511-1.1	S28P	Pathogenic	0.828
SLC26A4	O43511-1.1	S28Q	Pathogenic	0.502
SLC26A4	O43511-1.1	S28R	Neutral	0.244
SLC26A4	O43511-1.1	S28T	Pathogenic	0.554
SLC26A4	O43511-1.1	S28V	Pathogenic	0.802
SLC26A4	O43511-1.1	S28W	Neutral	0.285
SLC26A4	O43511-1.1	S28Y	Neutral	0.468
SLC26A4	O43511-1.1	E29A	Neutral	0.4
SLC26A4	O43511-1.1	E29C	Pathogenic	0.907
SLC26A4	O43511-1.1	E29D	Neutral	0.249
SLC26A4	O43511-1.1	E29F	Pathogenic	0.758
SLC26A4	O43511-1.1	E29G	Neutral	0.39
SLC26A4	O43511-1.1	E29H	Pathogenic	0.611
SLC26A4	O43511-1.1	E29I	Pathogenic	0.836
SLC26A4	O43511-1.1	E29K	Neutral	0.299
SLC26A4	O43511-1.1	E29L	Pathogenic	0.842
SLC26A4	O43511-1.1	E29M	Pathogenic	0.76
SLC26A4	O43511-1.1	E29N	Pathogenic	0.635
SLC26A4	O43511-1.1	E29P	Pathogenic	0.616
SLC26A4	O43511-1.1	E29Q	Neutral	0.348
SLC26A4	O43511-1.1	E29R	Neutral	0.322
SLC26A4	O43511-1.1	E29S	Neutral	0.332
SLC26A4	O43511-1.1	E29T	Pathogenic	0.687
SLC26A4	O43511-1.1	E29V	Pathogenic	0.84
SLC26A4	O43511-1.1	E29W	Neutral	0.425
SLC26A4	O43511-1.1	E29Y	Pathogenic	0.62
SLC26A4	O43511-1.1	L30A	Neutral	0.003
SLC26A4	O43511-1.1	L30C	Neutral	0.009
SLC26A4	O43511-1.1	L30D	Neutral	0.046
SLC26A4	O43511-1.1	L30E	Neutral	0.054
SLC26A4	O43511-1.1	L30F	Neutral	0.02
SLC26A4	O43511-1.1	L30G	Neutral	0.009
SLC26A4	O43511-1.1	L30H	Neutral	0.104
SLC26A4	O43511-1.1	L30I	Neutral	0.008
SLC26A4	O43511-1.1	L30K	Neutral	0.029
SLC26A4	O43511-1.1	L30M	Neutral	0.007
SLC26A4	O43511-1.1	L30N	Neutral	0.031
SLC26A4	O43511-1.1	L30P	Neutral	0.039
SLC26A4	O43511-1.1	L30Q	Neutral	0.04
SLC26A4	O43511-1.1	L30R	Neutral	0.016
SLC26A4	O43511-1.1	L30S	Neutral	0.007
SLC26A4	O43511-1.1	L30T	Neutral	0.01
SLC26A4	O43511-1.1	L30V	Neutral	0.006
SLC26A4	O43511-1.1	L30W	Neutral	0.019
SLC26A4	O43511-1.1	L30Y	Neutral	0.023
SLC26A4	O43511-1.1	A31C	Neutral	0.199
SLC26A4	O43511-1.1	A31D	Neutral	0.406
SLC26A4	O43511-1.1	A31E	Neutral	0.137
SLC26A4	O43511-1.1	A31F	Neutral	0.074
SLC26A4	O43511-1.1	A31G	Neutral	0.222
SLC26A4	O43511-1.1	A31H	Neutral	0.222
SLC26A4	O43511-1.1	A31I	Neutral	0.061
SLC26A4	O43511-1.1	A31K	Neutral	0.041
SLC26A4	O43511-1.1	A31L	Neutral	0.064
SLC26A4	O43511-1.1	A31M	Neutral	0.075
SLC26A4	O43511-1.1	A31N	Neutral	0.368
SLC26A4	O43511-1.1	A31P	Neutral	0.315
SLC26A4	O43511-1.1	A31Q	Neutral	0.13
SLC26A4	O43511-1.1	A31R	Neutral	0.023
SLC26A4	O43511-1.1	A31S	Neutral	0.201
SLC26A4	O43511-1.1	A31T	Neutral	0.187
SLC26A4	O43511-1.1	A31V	Neutral	0.088
SLC26A4	O43511-1.1	A31W	Neutral	0.037
SLC26A4	O43511-1.1	A31Y	Neutral	0.078
SLC26A4	O43511-1.1	F32A	Pathogenic	0.644
SLC26A4	O43511-1.1	F32C	Pathogenic	0.847
SLC26A4	O43511-1.1	F32D	Pathogenic	0.877
SLC26A4	O43511-1.1	F32E	Pathogenic	0.944
SLC26A4	O43511-1.1	F32G	Pathogenic	0.578
SLC26A4	O43511-1.1	F32H	Pathogenic	0.894
SLC26A4	O43511-1.1	F32I	Pathogenic	0.912
SLC26A4	O43511-1.1	F32K	Pathogenic	0.979
SLC26A4	O43511-1.1	F32L	Pathogenic	0.91
SLC26A4	O43511-1.1	F32M	Pathogenic	0.894
SLC26A4	O43511-1.1	F32N	Pathogenic	0.905
SLC26A4	O43511-1.1	F32P	Pathogenic	0.96
SLC26A4	O43511-1.1	F32Q	Pathogenic	0.961
SLC26A4	O43511-1.1	F32R	Pathogenic	0.963
SLC26A4	O43511-1.1	F32S	Pathogenic	0.675
SLC26A4	O43511-1.1	F32T	Pathogenic	0.852
SLC26A4	O43511-1.1	F32V	Pathogenic	0.877
SLC26A4	O43511-1.1	F32W	Pathogenic	0.668
SLC26A4	O43511-1.1	F32Y	Pathogenic	0.539
SLC26A4	O43511-1.1	Q33A	Neutral	0.093
SLC26A4	O43511-1.1	Q33C	Neutral	0.43
SLC26A4	O43511-1.1	Q33D	Neutral	0.13
SLC26A4	O43511-1.1	Q33E	Neutral	0.081
SLC26A4	O43511-1.1	Q33F	Neutral	0.431
SLC26A4	O43511-1.1	Q33G	Neutral	0.09
SLC26A4	O43511-1.1	Q33H	Neutral	0.276
SLC26A4	O43511-1.1	Q33I	Pathogenic	0.554
SLC26A4	O43511-1.1	Q33K	Neutral	0.07
SLC26A4	O43511-1.1	Q33L	Neutral	0.391
SLC26A4	O43511-1.1	Q33M	Neutral	0.16
SLC26A4	O43511-1.1	Q33N	Neutral	0.167
SLC26A4	O43511-1.1	Q33P	Neutral	0.199
SLC26A4	O43511-1.1	Q33R	Neutral	0.04
SLC26A4	O43511-1.1	Q33S	Neutral	0.071
SLC26A4	O43511-1.1	Q33T	Neutral	0.253
SLC26A4	O43511-1.1	Q33V	Neutral	0.447
SLC26A4	O43511-1.1	Q33W	Neutral	0.082
SLC26A4	O43511-1.1	Q33Y	Neutral	0.165
SLC26A4	O43511-1.1	Q34A	Neutral	0.284
SLC26A4	O43511-1.1	Q34C	Pathogenic	0.745
SLC26A4	O43511-1.1	Q34D	Neutral	0.367
SLC26A4	O43511-1.1	Q34E	Neutral	0.254
SLC26A4	O43511-1.1	Q34F	Pathogenic	0.746
SLC26A4	O43511-1.1	Q34G	Neutral	0.276
SLC26A4	O43511-1.1	Q34H	Pathogenic	0.596
SLC26A4	O43511-1.1	Q34I	Pathogenic	0.827
SLC26A4	O43511-1.1	Q34K	Neutral	0.225
SLC26A4	O43511-1.1	Q34L	Pathogenic	0.713
SLC26A4	O43511-1.1	Q34M	Neutral	0.424
SLC26A4	O43511-1.1	Q34N	Neutral	0.437
SLC26A4	O43511-1.1	Q34P	Neutral	0.489
SLC26A4	O43511-1.1	Q34R	Neutral	0.138
SLC26A4	O43511-1.1	Q34S	Neutral	0.228
SLC26A4	O43511-1.1	Q34T	Pathogenic	0.567
SLC26A4	O43511-1.1	Q34V	Pathogenic	0.758
SLC26A4	O43511-1.1	Q34W	Neutral	0.256
SLC26A4	O43511-1.1	Q34Y	Neutral	0.432
SLC26A4	O43511-1.1	Q35A	Neutral	0.128
SLC26A4	O43511-1.1	Q35C	Pathogenic	0.519
SLC26A4	O43511-1.1	Q35D	Neutral	0.176
SLC26A4	O43511-1.1	Q35E	Neutral	0.112
SLC26A4	O43511-1.1	Q35F	Pathogenic	0.52
SLC26A4	O43511-1.1	Q35G	Neutral	0.124
SLC26A4	O43511-1.1	Q35H	Neutral	0.353
SLC26A4	O43511-1.1	Q35I	Pathogenic	0.639
SLC26A4	O43511-1.1	Q35K	Neutral	0.097
SLC26A4	O43511-1.1	Q35L	Neutral	0.478
SLC26A4	O43511-1.1	Q35M	Neutral	0.214
SLC26A4	O43511-1.1	Q35N	Neutral	0.223
SLC26A4	O43511-1.1	Q35P	Neutral	0.262
SLC26A4	O43511-1.1	Q35R	Neutral	0.056
SLC26A4	O43511-1.1	Q35S	Neutral	0.099
SLC26A4	O43511-1.1	Q35T	Neutral	0.326
SLC26A4	O43511-1.1	Q35V	Pathogenic	0.536
SLC26A4	O43511-1.1	Q35W	Neutral	0.113
SLC26A4	O43511-1.1	Q35Y	Neutral	0.22
SLC26A4	O43511-1.1	H36A	Pathogenic	0.915
SLC26A4	O43511-1.1	H36C	Pathogenic	0.975
SLC26A4	O43511-1.1	H36D	Pathogenic	0.923
SLC26A4	O43511-1.1	H36E	Pathogenic	0.934
SLC26A4	O43511-1.1	H36F	Pathogenic	0.934
SLC26A4	O43511-1.1	H36G	Pathogenic	0.823
SLC26A4	O43511-1.1	H36I	Pathogenic	0.989
SLC26A4	O43511-1.1	H36K	Pathogenic	0.945
SLC26A4	O43511-1.1	H36L	Pathogenic	0.99
SLC26A4	O43511-1.1	H36M	Pathogenic	0.983
SLC26A4	O43511-1.1	H36N	Pathogenic	0.799
SLC26A4	O43511-1.1	H36P	Pathogenic	0.963
SLC26A4	O43511-1.1	H36Q	Pathogenic	0.954
SLC26A4	O43511-1.1	H36R	Pathogenic	0.826
SLC26A4	O43511-1.1	H36S	Pathogenic	0.876
SLC26A4	O43511-1.1	H36T	Pathogenic	0.973
SLC26A4	O43511-1.1	H36V	Pathogenic	0.988
SLC26A4	O43511-1.1	H36W	Pathogenic	0.87
SLC26A4	O43511-1.1	H36Y	Pathogenic	0.645
SLC26A4	O43511-1.1	E37A	Neutral	0.333
SLC26A4	O43511-1.1	E37C	Pathogenic	0.88
SLC26A4	O43511-1.1	E37D	Neutral	0.199
SLC26A4	O43511-1.1	E37F	Pathogenic	0.701
SLC26A4	O43511-1.1	E37G	Neutral	0.324
SLC26A4	O43511-1.1	E37H	Pathogenic	0.541
SLC26A4	O43511-1.1	E37I	Pathogenic	0.793
SLC26A4	O43511-1.1	E37K	Neutral	0.243
SLC26A4	O43511-1.1	E37L	Pathogenic	0.799
SLC26A4	O43511-1.1	E37M	Pathogenic	0.704
SLC26A4	O43511-1.1	E37N	Pathogenic	0.567
SLC26A4	O43511-1.1	E37P	Pathogenic	0.546
SLC26A4	O43511-1.1	E37Q	Neutral	0.286
SLC26A4	O43511-1.1	E37R	Neutral	0.263
SLC26A4	O43511-1.1	E37S	Neutral	0.271
SLC26A4	O43511-1.1	E37T	Pathogenic	0.622
SLC26A4	O43511-1.1	E37V	Pathogenic	0.797
SLC26A4	O43511-1.1	E37W	Neutral	0.357
SLC26A4	O43511-1.1	E37Y	Pathogenic	0.551
SLC26A4	O43511-1.1	R38A	Neutral	0.044
SLC26A4	O43511-1.1	R38C	Neutral	0.252
SLC26A4	O43511-1.1	R38D	Neutral	0.292
SLC26A4	O43511-1.1	R38E	Neutral	0.18
SLC26A4	O43511-1.1	R38F	Pathogenic	0.693
SLC26A4	O43511-1.1	R38G	Neutral	0.042
SLC26A4	O43511-1.1	R38H	Neutral	0.197
SLC26A4	O43511-1.1	R38I	Pathogenic	0.577
SLC26A4	O43511-1.1	R38K	Neutral	0.168
SLC26A4	O43511-1.1	R38L	Neutral	0.414
SLC26A4	O43511-1.1	R38M	Neutral	0.297
SLC26A4	O43511-1.1	R38N	Neutral	0.107
SLC26A4	O43511-1.1	R38P	Neutral	0.182
SLC26A4	O43511-1.1	R38Q	Neutral	0.104
SLC26A4	O43511-1.1	R38S	Neutral	0.064
SLC26A4	O43511-1.1	R38T	Neutral	0.132
SLC26A4	O43511-1.1	R38V	Neutral	0.421
SLC26A4	O43511-1.1	R38W	Pathogenic	0.633
SLC26A4	O43511-1.1	R38Y	Pathogenic	0.67
SLC26A4	O43511-1.1	R39A	Neutral	0.026
SLC26A4	O43511-1.1	R39C	Neutral	0.162
SLC26A4	O43511-1.1	R39D	Neutral	0.192
SLC26A4	O43511-1.1	R39E	Neutral	0.112
SLC26A4	O43511-1.1	R39F	Pathogenic	0.564
SLC26A4	O43511-1.1	R39G	Neutral	0.025
SLC26A4	O43511-1.1	R39H	Neutral	0.123
SLC26A4	O43511-1.1	R39I	Neutral	0.439
SLC26A4	O43511-1.1	R39K	Neutral	0.103
SLC26A4	O43511-1.1	R39L	Neutral	0.289
SLC26A4	O43511-1.1	R39M	Neutral	0.195
SLC26A4	O43511-1.1	R39N	Neutral	0.065
SLC26A4	O43511-1.1	R39P	Neutral	0.113
SLC26A4	O43511-1.1	R39Q	Neutral	0.063
SLC26A4	O43511-1.1	R39S	Neutral	0.038
SLC26A4	O43511-1.1	R39T	Neutral	0.08
SLC26A4	O43511-1.1	R39V	Neutral	0.294
SLC26A4	O43511-1.1	R39W	Neutral	0.497
SLC26A4	O43511-1.1	R39Y	Pathogenic	0.537
SLC26A4	O43511-1.1	L40A	Neutral	0.001
SLC26A4	O43511-1.1	L40C	Neutral	0.004
SLC26A4	O43511-1.1	L40D	Neutral	0.022
SLC26A4	O43511-1.1	L40E	Neutral	0.026
SLC26A4	O43511-1.1	L40F	Neutral	0.009
SLC26A4	O43511-1.1	L40G	Neutral	0.004
SLC26A4	O43511-1.1	L40H	Neutral	0.051
SLC26A4	O43511-1.1	L40I	Neutral	0.004
SLC26A4	O43511-1.1	L40K	Neutral	0.014
SLC26A4	O43511-1.1	L40M	Neutral	0.003
SLC26A4	O43511-1.1	L40N	Neutral	0.015
SLC26A4	O43511-1.1	L40P	Neutral	0.019
SLC26A4	O43511-1.1	L40Q	Neutral	0.019
SLC26A4	O43511-1.1	L40R	Neutral	0.008
SLC26A4	O43511-1.1	L40S	Neutral	0.003
SLC26A4	O43511-1.1	L40T	Neutral	0.005
SLC26A4	O43511-1.1	L40V	Neutral	0.003
SLC26A4	O43511-1.1	L40W	Neutral	0.009
SLC26A4	O43511-1.1	L40Y	Neutral	0.011
SLC26A4	O43511-1.1	Q41A	Neutral	0.159
SLC26A4	O43511-1.1	Q41C	Pathogenic	0.581
SLC26A4	O43511-1.1	Q41D	Neutral	0.216
SLC26A4	O43511-1.1	Q41E	Neutral	0.139
SLC26A4	O43511-1.1	Q41F	Pathogenic	0.582
SLC26A4	O43511-1.1	Q41G	Neutral	0.153
SLC26A4	O43511-1.1	Q41H	Neutral	0.412
SLC26A4	O43511-1.1	Q41I	Pathogenic	0.694
SLC26A4	O43511-1.1	Q41K	Neutral	0.121
SLC26A4	O43511-1.1	Q41L	Pathogenic	0.541
SLC26A4	O43511-1.1	Q41M	Neutral	0.259
SLC26A4	O43511-1.1	Q41N	Neutral	0.269
SLC26A4	O43511-1.1	Q41P	Neutral	0.313
SLC26A4	O43511-1.1	Q41R	Neutral	0.071
SLC26A4	O43511-1.1	Q41S	Neutral	0.123
SLC26A4	O43511-1.1	Q41T	Neutral	0.384
SLC26A4	O43511-1.1	Q41V	Pathogenic	0.597
SLC26A4	O43511-1.1	Q41W	Neutral	0.141
SLC26A4	O43511-1.1	Q41Y	Neutral	0.266
SLC26A4	O43511-1.1	E42A	Neutral	0.023
SLC26A4	O43511-1.1	E42C	Neutral	0.255
SLC26A4	O43511-1.1	E42D	Neutral	0.011
SLC26A4	O43511-1.1	E42F	Neutral	0.099
SLC26A4	O43511-1.1	E42G	Neutral	0.022
SLC26A4	O43511-1.1	E42H	Neutral	0.052
SLC26A4	O43511-1.1	E42I	Neutral	0.152
SLC26A4	O43511-1.1	E42K	Neutral	0.015
SLC26A4	O43511-1.1	E42L	Neutral	0.157
SLC26A4	O43511-1.1	E42M	Neutral	0.1
SLC26A4	O43511-1.1	E42N	Neutral	0.057
SLC26A4	O43511-1.1	E42P	Neutral	0.053
SLC26A4	O43511-1.1	E42Q	Neutral	0.018
SLC26A4	O43511-1.1	E42R	Neutral	0.016
SLC26A4	O43511-1.1	E42S	Neutral	0.017
SLC26A4	O43511-1.1	E42T	Neutral	0.071
SLC26A4	O43511-1.1	E42V	Neutral	0.155
SLC26A4	O43511-1.1	E42W	Neutral	0.025
SLC26A4	O43511-1.1	E42Y	Neutral	0.054
SLC26A4	O43511-1.1	R43A	Neutral	0.046
SLC26A4	O43511-1.1	R43C	Neutral	0.261
SLC26A4	O43511-1.1	R43D	Neutral	0.302
SLC26A4	O43511-1.1	R43E	Neutral	0.187
SLC26A4	O43511-1.1	R43F	Pathogenic	0.702
SLC26A4	O43511-1.1	R43G	Neutral	0.044
SLC26A4	O43511-1.1	R43H	Neutral	0.204
SLC26A4	O43511-1.1	R43I	Pathogenic	0.588
SLC26A4	O43511-1.1	R43K	Neutral	0.174
SLC26A4	O43511-1.1	R43L	Neutral	0.425
SLC26A4	O43511-1.1	R43M	Neutral	0.306
SLC26A4	O43511-1.1	R43N	Neutral	0.112
SLC26A4	O43511-1.1	R43P	Neutral	0.189
SLC26A4	O43511-1.1	R43Q	Neutral	0.109
SLC26A4	O43511-1.1	R43S	Neutral	0.067
SLC26A4	O43511-1.1	R43T	Neutral	0.137
SLC26A4	O43511-1.1	R43V	Neutral	0.432
SLC26A4	O43511-1.1	R43W	Pathogenic	0.644
SLC26A4	O43511-1.1	R43Y	Pathogenic	0.68
SLC26A4	O43511-1.1	K44A	Neutral	0.224
SLC26A4	O43511-1.1	K44C	Pathogenic	0.679
SLC26A4	O43511-1.1	K44D	Pathogenic	0.563
SLC26A4	O43511-1.1	K44E	Neutral	0.406
SLC26A4	O43511-1.1	K44F	Pathogenic	0.934
SLC26A4	O43511-1.1	K44G	Neutral	0.217
SLC26A4	O43511-1.1	K44H	Pathogenic	0.755
SLC26A4	O43511-1.1	K44I	Pathogenic	0.895
SLC26A4	O43511-1.1	K44L	Pathogenic	0.816
SLC26A4	O43511-1.1	K44M	Pathogenic	0.726
SLC26A4	O43511-1.1	K44N	Neutral	0.43
SLC26A4	O43511-1.1	K44P	Neutral	0.41
SLC26A4	O43511-1.1	K44Q	Neutral	0.422
SLC26A4	O43511-1.1	K44R	Neutral	0.411
SLC26A4	O43511-1.1	K44S	Neutral	0.177
SLC26A4	O43511-1.1	K44T	Neutral	0.487
SLC26A4	O43511-1.1	K44V	Pathogenic	0.694
SLC26A4	O43511-1.1	K44W	Pathogenic	0.77
SLC26A4	O43511-1.1	K44Y	Pathogenic	0.881
SLC26A4	O43511-1.1	T45A	Pathogenic	0.876
SLC26A4	O43511-1.1	T45C	Pathogenic	0.963
SLC26A4	O43511-1.1	T45D	Pathogenic	0.966
SLC26A4	O43511-1.1	T45E	Pathogenic	0.942
SLC26A4	O43511-1.1	T45F	Pathogenic	0.887
SLC26A4	O43511-1.1	T45G	Pathogenic	0.918
SLC26A4	O43511-1.1	T45H	Pathogenic	0.967
SLC26A4	O43511-1.1	T45I	Pathogenic	0.864
SLC26A4	O43511-1.1	T45K	Pathogenic	0.813
SLC26A4	O43511-1.1	T45L	Pathogenic	0.869
SLC26A4	O43511-1.1	T45M	Pathogenic	0.888
SLC26A4	O43511-1.1	T45N	Pathogenic	0.936
SLC26A4	O43511-1.1	T45P	Pathogenic	0.972
SLC26A4	O43511-1.1	T45Q	Pathogenic	0.938
SLC26A4	O43511-1.1	T45R	Pathogenic	0.706
SLC26A4	O43511-1.1	T45S	Pathogenic	0.808
SLC26A4	O43511-1.1	T45V	Pathogenic	0.903
SLC26A4	O43511-1.1	T45W	Pathogenic	0.649
SLC26A4	O43511-1.1	T45Y	Pathogenic	0.891
SLC26A4	O43511-1.1	L46A	Neutral	0.032
SLC26A4	O43511-1.1	L46C	Neutral	0.092
SLC26A4	O43511-1.1	L46D	Neutral	0.345
SLC26A4	O43511-1.1	L46E	Neutral	0.383
SLC26A4	O43511-1.1	L46F	Neutral	0.179
SLC26A4	O43511-1.1	L46G	Neutral	0.092
SLC26A4	O43511-1.1	L46H	Pathogenic	0.557
SLC26A4	O43511-1.1	L46I	Neutral	0.081
SLC26A4	O43511-1.1	L46K	Neutral	0.245
SLC26A4	O43511-1.1	L46M	Neutral	0.071
SLC26A4	O43511-1.1	L46N	Neutral	0.26
SLC26A4	O43511-1.1	L46P	Neutral	0.308
SLC26A4	O43511-1.1	L46Q	Neutral	0.313
SLC26A4	O43511-1.1	L46R	Neutral	0.152
SLC26A4	O43511-1.1	L46S	Neutral	0.071
SLC26A4	O43511-1.1	L46T	Neutral	0.096
SLC26A4	O43511-1.1	L46V	Neutral	0.061
SLC26A4	O43511-1.1	L46W	Neutral	0.173
SLC26A4	O43511-1.1	L46Y	Neutral	0.207
SLC26A4	O43511-1.1	R47A	Neutral	0.07
SLC26A4	O43511-1.1	R47C	Neutral	0.357
SLC26A4	O43511-1.1	R47D	Neutral	0.405
SLC26A4	O43511-1.1	R47E	Neutral	0.265
SLC26A4	O43511-1.1	R47F	Pathogenic	0.788
SLC26A4	O43511-1.1	R47G	Neutral	0.068
SLC26A4	O43511-1.1	R47H	Neutral	0.287
SLC26A4	O43511-1.1	R47I	Pathogenic	0.692
SLC26A4	O43511-1.1	R47K	Neutral	0.249
SLC26A4	O43511-1.1	R47L	Pathogenic	0.538
SLC26A4	O43511-1.1	R47M	Neutral	0.41
SLC26A4	O43511-1.1	R47N	Neutral	0.165
SLC26A4	O43511-1.1	R47P	Neutral	0.268
SLC26A4	O43511-1.1	R47Q	Neutral	0.161
SLC26A4	O43511-1.1	R47S	Neutral	0.102
SLC26A4	O43511-1.1	R47T	Neutral	0.2
SLC26A4	O43511-1.1	R47V	Pathogenic	0.544
SLC26A4	O43511-1.1	R47W	Pathogenic	0.739
SLC26A4	O43511-1.1	R47Y	Pathogenic	0.769
SLC26A4	O43511-1.1	E48A	Neutral	0.158
SLC26A4	O43511-1.1	E48C	Pathogenic	0.734
SLC26A4	O43511-1.1	E48D	Neutral	0.086
SLC26A4	O43511-1.1	E48F	Neutral	0.468
SLC26A4	O43511-1.1	E48G	Neutral	0.153
SLC26A4	O43511-1.1	E48H	Neutral	0.307
SLC26A4	O43511-1.1	E48I	Pathogenic	0.59
SLC26A4	O43511-1.1	E48K	Neutral	0.107
SLC26A4	O43511-1.1	E48L	Pathogenic	0.6
SLC26A4	O43511-1.1	E48M	Neutral	0.472
SLC26A4	O43511-1.1	E48N	Neutral	0.329
SLC26A4	O43511-1.1	E48P	Neutral	0.311
SLC26A4	O43511-1.1	E48Q	Neutral	0.131
SLC26A4	O43511-1.1	E48R	Neutral	0.118
SLC26A4	O43511-1.1	E48S	Neutral	0.123
SLC26A4	O43511-1.1	E48T	Neutral	0.382
SLC26A4	O43511-1.1	E48V	Pathogenic	0.596
SLC26A4	O43511-1.1	E48W	Neutral	0.172
SLC26A4	O43511-1.1	E48Y	Neutral	0.315
SLC26A4	O43511-1.1	S49A	Neutral	0.054
SLC26A4	O43511-1.1	S49C	Neutral	0.115
SLC26A4	O43511-1.1	S49D	Neutral	0.055
SLC26A4	O43511-1.1	S49E	Neutral	0.026
SLC26A4	O43511-1.1	S49F	Neutral	0.021
SLC26A4	O43511-1.1	S49G	Neutral	0.052
SLC26A4	O43511-1.1	S49H	Neutral	0.041
SLC26A4	O43511-1.1	S49I	Neutral	0.033
SLC26A4	O43511-1.1	S49K	Neutral	0.007
SLC26A4	O43511-1.1	S49L	Neutral	0.034
SLC26A4	O43511-1.1	S49M	Neutral	0.021
SLC26A4	O43511-1.1	S49N	Neutral	0.024
SLC26A4	O43511-1.1	S49P	Neutral	0.108
SLC26A4	O43511-1.1	S49Q	Neutral	0.025
SLC26A4	O43511-1.1	S49R	Neutral	0.008
SLC26A4	O43511-1.1	S49T	Neutral	0.03
SLC26A4	O43511-1.1	S49V	Neutral	0.092
SLC26A4	O43511-1.1	S49W	Neutral	0.01
SLC26A4	O43511-1.1	S49Y	Neutral	0.022
SLC26A4	O43511-1.1	L50A	Neutral	0.278
SLC26A4	O43511-1.1	L50C	Pathogenic	0.54
SLC26A4	O43511-1.1	L50D	Pathogenic	0.859
SLC26A4	O43511-1.1	L50E	Pathogenic	0.878
SLC26A4	O43511-1.1	L50F	Pathogenic	0.716
SLC26A4	O43511-1.1	L50G	Pathogenic	0.54
SLC26A4	O43511-1.1	L50H	Pathogenic	0.935
SLC26A4	O43511-1.1	L50I	Pathogenic	0.505
SLC26A4	O43511-1.1	L50K	Pathogenic	0.789
SLC26A4	O43511-1.1	L50M	Neutral	0.47
SLC26A4	O43511-1.1	L50N	Pathogenic	0.802
SLC26A4	O43511-1.1	L50P	Pathogenic	0.837
SLC26A4	O43511-1.1	L50Q	Pathogenic	0.84
SLC26A4	O43511-1.1	L50R	Pathogenic	0.674
SLC26A4	O43511-1.1	L50S	Neutral	0.47
SLC26A4	O43511-1.1	L50T	Pathogenic	0.549
SLC26A4	O43511-1.1	L50V	Neutral	0.429
SLC26A4	O43511-1.1	L50W	Pathogenic	0.707
SLC26A4	O43511-1.1	L50Y	Pathogenic	0.751
SLC26A4	O43511-1.1	A51C	Neutral	0.098
SLC26A4	O43511-1.1	A51D	Neutral	0.231
SLC26A4	O43511-1.1	A51E	Neutral	0.065
SLC26A4	O43511-1.1	A51F	Neutral	0.034
SLC26A4	O43511-1.1	A51G	Neutral	0.112
SLC26A4	O43511-1.1	A51H	Neutral	0.112
SLC26A4	O43511-1.1	A51I	Neutral	0.028
SLC26A4	O43511-1.1	A51K	Neutral	0.019
SLC26A4	O43511-1.1	A51L	Neutral	0.029
SLC26A4	O43511-1.1	A51M	Neutral	0.035
SLC26A4	O43511-1.1	A51N	Neutral	0.204
SLC26A4	O43511-1.1	A51P	Neutral	0.168
SLC26A4	O43511-1.1	A51Q	Neutral	0.061
SLC26A4	O43511-1.1	A51R	Neutral	0.01
SLC26A4	O43511-1.1	A51S	Neutral	0.1
SLC26A4	O43511-1.1	A51T	Neutral	0.092
SLC26A4	O43511-1.1	A51V	Neutral	0.041
SLC26A4	O43511-1.1	A51W	Neutral	0.017
SLC26A4	O43511-1.1	A51Y	Neutral	0.036
SLC26A4	O43511-1.1	K52A	Neutral	0.002
SLC26A4	O43511-1.1	K52C	Neutral	0.011
SLC26A4	O43511-1.1	K52D	Neutral	0.007
SLC26A4	O43511-1.1	K52E	Neutral	0.004
SLC26A4	O43511-1.1	K52F	Neutral	0.071
SLC26A4	O43511-1.1	K52G	Neutral	0.001
SLC26A4	O43511-1.1	K52H	Neutral	0.016
SLC26A4	O43511-1.1	K52I	Neutral	0.044
SLC26A4	O43511-1.1	K52L	Neutral	0.023
SLC26A4	O43511-1.1	K52M	Neutral	0.014
SLC26A4	O43511-1.1	K52N	Neutral	0.004
SLC26A4	O43511-1.1	K52P	Neutral	0.004
SLC26A4	O43511-1.1	K52Q	Neutral	0.004
SLC26A4	O43511-1.1	K52R	Neutral	0.004
SLC26A4	O43511-1.1	K52S	Neutral	0.001
SLC26A4	O43511-1.1	K52T	Neutral	0.005
SLC26A4	O43511-1.1	K52V	Neutral	0.012
SLC26A4	O43511-1.1	K52W	Neutral	0.018
SLC26A4	O43511-1.1	K52Y	Neutral	0.038
SLC26A4	O43511-1.1	C53A	Neutral	0.305
SLC26A4	O43511-1.1	C53D	Pathogenic	0.816
SLC26A4	O43511-1.1	C53E	Pathogenic	0.806
SLC26A4	O43511-1.1	C53F	Neutral	0.303
SLC26A4	O43511-1.1	C53G	Pathogenic	0.573
SLC26A4	O43511-1.1	C53H	Pathogenic	0.649
SLC26A4	O43511-1.1	C53I	Neutral	0.261
SLC26A4	O43511-1.1	C53K	Neutral	0.358
SLC26A4	O43511-1.1	C53L	Neutral	0.269
SLC26A4	O43511-1.1	C53M	Neutral	0.306
SLC26A4	O43511-1.1	C53N	Pathogenic	0.79
SLC26A4	O43511-1.1	C53P	Pathogenic	0.891
SLC26A4	O43511-1.1	C53Q	Pathogenic	0.659
SLC26A4	O43511-1.1	C53R	Neutral	0.236
SLC26A4	O43511-1.1	C53S	Pathogenic	0.503
SLC26A4	O43511-1.1	C53T	Pathogenic	0.598
SLC26A4	O43511-1.1	C53V	Pathogenic	0.511
SLC26A4	O43511-1.1	C53W	Neutral	0.093
SLC26A4	O43511-1.1	C53Y	Neutral	0.31
SLC26A4	O43511-1.1	C54A	Pathogenic	0.969
SLC26A4	O43511-1.1	C54D	Pathogenic	0.997
SLC26A4	O43511-1.1	C54E	Pathogenic	0.997
SLC26A4	O43511-1.1	C54F	Pathogenic	0.969
SLC26A4	O43511-1.1	C54G	Pathogenic	0.99
SLC26A4	O43511-1.1	C54H	Pathogenic	0.992
SLC26A4	O43511-1.1	C54I	Pathogenic	0.962
SLC26A4	O43511-1.1	C54K	Pathogenic	0.975
SLC26A4	O43511-1.1	C54L	Pathogenic	0.963
SLC26A4	O43511-1.1	C54M	Pathogenic	0.969
SLC26A4	O43511-1.1	C54N	Pathogenic	0.996
SLC26A4	O43511-1.1	C54P	Pathogenic	0.998
SLC26A4	O43511-1.1	C54Q	Pathogenic	0.993
SLC26A4	O43511-1.1	C54R	Pathogenic	0.956
SLC26A4	O43511-1.1	C54S	Pathogenic	0.986
SLC26A4	O43511-1.1	C54T	Pathogenic	0.991
SLC26A4	O43511-1.1	C54V	Pathogenic	0.987
SLC26A4	O43511-1.1	C54W	Pathogenic	0.88
SLC26A4	O43511-1.1	C54Y	Pathogenic	0.97
SLC26A4	O43511-1.1	S55A	Neutral	0.428
SLC26A4	O43511-1.1	S55C	Pathogenic	0.629
SLC26A4	O43511-1.1	S55D	Neutral	0.429
SLC26A4	O43511-1.1	S55E	Neutral	0.26
SLC26A4	O43511-1.1	S55F	Neutral	0.215
SLC26A4	O43511-1.1	S55G	Neutral	0.417
SLC26A4	O43511-1.1	S55H	Neutral	0.357
SLC26A4	O43511-1.1	S55I	Neutral	0.309
SLC26A4	O43511-1.1	S55K	Neutral	0.087
SLC26A4	O43511-1.1	S55L	Neutral	0.317
SLC26A4	O43511-1.1	S55M	Neutral	0.217
SLC26A4	O43511-1.1	S55N	Neutral	0.242
SLC26A4	O43511-1.1	S55P	Pathogenic	0.61
SLC26A4	O43511-1.1	S55Q	Neutral	0.248
SLC26A4	O43511-1.1	S55R	Neutral	0.095
SLC26A4	O43511-1.1	S55T	Neutral	0.288
SLC26A4	O43511-1.1	S55V	Pathogenic	0.569
SLC26A4	O43511-1.1	S55W	Neutral	0.115
SLC26A4	O43511-1.1	S55Y	Neutral	0.223
SLC26A4	O43511-1.1	C56A	Pathogenic	1.0
SLC26A4	O43511-1.1	C56D	Pathogenic	1.0
SLC26A4	O43511-1.1	C56E	Pathogenic	1.0
SLC26A4	O43511-1.1	C56F	Pathogenic	1.0
SLC26A4	O43511-1.1	C56G	Pathogenic	1.0
SLC26A4	O43511-1.1	C56H	Pathogenic	1.0
SLC26A4	O43511-1.1	C56I	Pathogenic	1.0
SLC26A4	O43511-1.1	C56K	Pathogenic	1.0
SLC26A4	O43511-1.1	C56L	Pathogenic	1.0
SLC26A4	O43511-1.1	C56M	Pathogenic	1.0
SLC26A4	O43511-1.1	C56N	Pathogenic	1.0
SLC26A4	O43511-1.1	C56P	Pathogenic	1.0
SLC26A4	O43511-1.1	C56Q	Pathogenic	1.0
SLC26A4	O43511-1.1	C56R	Pathogenic	1.0
SLC26A4	O43511-1.1	C56S	Pathogenic	1.0
SLC26A4	O43511-1.1	C56T	Pathogenic	1.0
SLC26A4	O43511-1.1	C56V	Pathogenic	1.0
SLC26A4	O43511-1.1	C56W	Pathogenic	0.999
SLC26A4	O43511-1.1	C56Y	Pathogenic	1.0
SLC26A4	O43511-1.1	S57A	Pathogenic	0.958
SLC26A4	O43511-1.1	S57C	Pathogenic	0.981
SLC26A4	O43511-1.1	S57D	Pathogenic	0.959
SLC26A4	O43511-1.1	S57E	Pathogenic	0.915
SLC26A4	O43511-1.1	S57F	Pathogenic	0.894
SLC26A4	O43511-1.1	S57G	Pathogenic	0.957
SLC26A4	O43511-1.1	S57H	Pathogenic	0.945
SLC26A4	O43511-1.1	S57I	Pathogenic	0.932
SLC26A4	O43511-1.1	S57K	Pathogenic	0.745
SLC26A4	O43511-1.1	S57L	Pathogenic	0.935
SLC26A4	O43511-1.1	S57M	Pathogenic	0.895
SLC26A4	O43511-1.1	S57N	Pathogenic	0.907
SLC26A4	O43511-1.1	S57P	Pathogenic	0.98
SLC26A4	O43511-1.1	S57Q	Pathogenic	0.91
SLC26A4	O43511-1.1	S57R	Pathogenic	0.764
SLC26A4	O43511-1.1	S57T	Pathogenic	0.926
SLC26A4	O43511-1.1	S57V	Pathogenic	0.976
SLC26A4	O43511-1.1	S57W	Pathogenic	0.8
SLC26A4	O43511-1.1	S57Y	Pathogenic	0.898
SLC26A4	O43511-1.1	R58A	Neutral	0.076
SLC26A4	O43511-1.1	R58C	Neutral	0.377
SLC26A4	O43511-1.1	R58D	Neutral	0.426
SLC26A4	O43511-1.1	R58E	Neutral	0.282
SLC26A4	O43511-1.1	R58F	Pathogenic	0.802
SLC26A4	O43511-1.1	R58G	Neutral	0.073
SLC26A4	O43511-1.1	R58H	Neutral	0.305
SLC26A4	O43511-1.1	R58I	Pathogenic	0.71
SLC26A4	O43511-1.1	R58K	Neutral	0.265
SLC26A4	O43511-1.1	R58L	Pathogenic	0.559
SLC26A4	O43511-1.1	R58M	Neutral	0.431
SLC26A4	O43511-1.1	R58N	Neutral	0.178
SLC26A4	O43511-1.1	R58P	Neutral	0.286
SLC26A4	O43511-1.1	R58Q	Neutral	0.173
SLC26A4	O43511-1.1	R58S	Neutral	0.11
SLC26A4	O43511-1.1	R58T	Neutral	0.214
SLC26A4	O43511-1.1	R58V	Pathogenic	0.566
SLC26A4	O43511-1.1	R58W	Pathogenic	0.756
SLC26A4	O43511-1.1	R58Y	Pathogenic	0.784
SLC26A4	O43511-1.1	K59A	Neutral	0.445
SLC26A4	O43511-1.1	K59C	Pathogenic	0.855
SLC26A4	O43511-1.1	K59D	Pathogenic	0.782
SLC26A4	O43511-1.1	K59E	Pathogenic	0.656
SLC26A4	O43511-1.1	K59F	Pathogenic	0.975
SLC26A4	O43511-1.1	K59G	Neutral	0.435
SLC26A4	O43511-1.1	K59H	Pathogenic	0.896
SLC26A4	O43511-1.1	K59I	Pathogenic	0.96
SLC26A4	O43511-1.1	K59L	Pathogenic	0.925
SLC26A4	O43511-1.1	K59M	Pathogenic	0.881
SLC26A4	O43511-1.1	K59N	Pathogenic	0.678
SLC26A4	O43511-1.1	K59P	Pathogenic	0.659
SLC26A4	O43511-1.1	K59Q	Pathogenic	0.67
SLC26A4	O43511-1.1	K59R	Pathogenic	0.66
SLC26A4	O43511-1.1	K59S	Neutral	0.374
SLC26A4	O43511-1.1	K59T	Pathogenic	0.726
SLC26A4	O43511-1.1	K59V	Pathogenic	0.863
SLC26A4	O43511-1.1	K59W	Pathogenic	0.903
SLC26A4	O43511-1.1	K59Y	Pathogenic	0.954
SLC26A4	O43511-1.1	R60A	Pathogenic	0.677
SLC26A4	O43511-1.1	R60C	Pathogenic	0.939
SLC26A4	O43511-1.1	R60D	Pathogenic	0.95
SLC26A4	O43511-1.1	R60E	Pathogenic	0.909
SLC26A4	O43511-1.1	R60F	Pathogenic	0.99
SLC26A4	O43511-1.1	R60G	Pathogenic	0.668
SLC26A4	O43511-1.1	R60H	Pathogenic	0.918
SLC26A4	O43511-1.1	R60I	Pathogenic	0.984
SLC26A4	O43511-1.1	R60K	Pathogenic	0.902
SLC26A4	O43511-1.1	R60L	Pathogenic	0.97
SLC26A4	O43511-1.1	R60M	Pathogenic	0.951
SLC26A4	O43511-1.1	R60N	Pathogenic	0.846
SLC26A4	O43511-1.1	R60P	Pathogenic	0.91
SLC26A4	O43511-1.1	R60Q	Pathogenic	0.842
SLC26A4	O43511-1.1	R60S	Pathogenic	0.759
SLC26A4	O43511-1.1	R60T	Pathogenic	0.874
SLC26A4	O43511-1.1	R60V	Pathogenic	0.971
SLC26A4	O43511-1.1	R60W	Pathogenic	0.987
SLC26A4	O43511-1.1	R60Y	Pathogenic	0.989
SLC26A4	O43511-1.1	A61C	Pathogenic	0.724
SLC26A4	O43511-1.1	A61D	Pathogenic	0.879
SLC26A4	O43511-1.1	A61E	Pathogenic	0.627
SLC26A4	O43511-1.1	A61F	Neutral	0.459
SLC26A4	O43511-1.1	A61G	Pathogenic	0.751
SLC26A4	O43511-1.1	A61H	Pathogenic	0.752
SLC26A4	O43511-1.1	A61I	Neutral	0.409
SLC26A4	O43511-1.1	A61K	Neutral	0.312
SLC26A4	O43511-1.1	A61L	Neutral	0.418
SLC26A4	O43511-1.1	A61M	Neutral	0.463
SLC26A4	O43511-1.1	A61N	Pathogenic	0.86
SLC26A4	O43511-1.1	A61P	Pathogenic	0.83
SLC26A4	O43511-1.1	A61Q	Pathogenic	0.612
SLC26A4	O43511-1.1	A61R	Neutral	0.201
SLC26A4	O43511-1.1	A61S	Pathogenic	0.727
SLC26A4	O43511-1.1	A61T	Pathogenic	0.709
SLC26A4	O43511-1.1	A61V	Pathogenic	0.504
SLC26A4	O43511-1.1	A61W	Neutral	0.288
SLC26A4	O43511-1.1	A61Y	Neutral	0.472
SLC26A4	O43511-1.1	F62A	Neutral	0.098
SLC26A4	O43511-1.1	F62C	Neutral	0.25
SLC26A4	O43511-1.1	F62D	Neutral	0.3
SLC26A4	O43511-1.1	F62E	Pathogenic	0.504
SLC26A4	O43511-1.1	F62G	Neutral	0.076
SLC26A4	O43511-1.1	F62H	Neutral	0.337
SLC26A4	O43511-1.1	F62I	Neutral	0.384
SLC26A4	O43511-1.1	F62K	Pathogenic	0.741
SLC26A4	O43511-1.1	F62L	Neutral	0.378
SLC26A4	O43511-1.1	F62M	Neutral	0.336
SLC26A4	O43511-1.1	F62N	Neutral	0.364
SLC26A4	O43511-1.1	F62P	Pathogenic	0.593
SLC26A4	O43511-1.1	F62Q	Pathogenic	0.599
SLC26A4	O43511-1.1	F62R	Pathogenic	0.613
SLC26A4	O43511-1.1	F62S	Neutral	0.111
SLC26A4	O43511-1.1	F62T	Neutral	0.257
SLC26A4	O43511-1.1	F62V	Neutral	0.3
SLC26A4	O43511-1.1	F62W	Neutral	0.108
SLC26A4	O43511-1.1	F62Y	Neutral	0.066
SLC26A4	O43511-1.1	G63A	Neutral	0.05
SLC26A4	O43511-1.1	G63C	Neutral	0.121
SLC26A4	O43511-1.1	G63D	Neutral	0.029
SLC26A4	O43511-1.1	G63E	Neutral	0.027
SLC26A4	O43511-1.1	G63F	Neutral	0.011
SLC26A4	O43511-1.1	G63H	Neutral	0.022
SLC26A4	O43511-1.1	G63I	Neutral	0.035
SLC26A4	O43511-1.1	G63K	Neutral	0.007
SLC26A4	O43511-1.1	G63L	Neutral	0.036
SLC26A4	O43511-1.1	G63M	Neutral	0.022
SLC26A4	O43511-1.1	G63N	Neutral	0.012
SLC26A4	O43511-1.1	G63P	Neutral	0.06
SLC26A4	O43511-1.1	G63Q	Neutral	0.025
SLC26A4	O43511-1.1	G63R	Neutral	0.004
SLC26A4	O43511-1.1	G63S	Neutral	0.042
SLC26A4	O43511-1.1	G63T	Neutral	0.062
SLC26A4	O43511-1.1	G63V	Neutral	0.051
SLC26A4	O43511-1.1	G63W	Neutral	0.001
SLC26A4	O43511-1.1	G63Y	Neutral	0.012
SLC26A4	O43511-1.1	V64A	Neutral	0.023
SLC26A4	O43511-1.1	V64C	Neutral	0.125
SLC26A4	O43511-1.1	V64D	Neutral	0.269
SLC26A4	O43511-1.1	V64E	Neutral	0.233
SLC26A4	O43511-1.1	V64F	Neutral	0.071
SLC26A4	O43511-1.1	V64G	Neutral	0.066
SLC26A4	O43511-1.1	V64H	Neutral	0.353
SLC26A4	O43511-1.1	V64I	Neutral	0.008
SLC26A4	O43511-1.1	V64K	Neutral	0.076
SLC26A4	O43511-1.1	V64L	Neutral	0.031
SLC26A4	O43511-1.1	V64M	Neutral	0.037
SLC26A4	O43511-1.1	V64N	Neutral	0.33
SLC26A4	O43511-1.1	V64P	Neutral	0.237
SLC26A4	O43511-1.1	V64Q	Neutral	0.221
SLC26A4	O43511-1.1	V64R	Neutral	0.083
SLC26A4	O43511-1.1	V64S	Neutral	0.097
SLC26A4	O43511-1.1	V64T	Neutral	0.069
SLC26A4	O43511-1.1	V64W	Neutral	0.068
SLC26A4	O43511-1.1	V64Y	Neutral	0.062
SLC26A4	O43511-1.1	L65A	Neutral	0.037
SLC26A4	O43511-1.1	L65C	Neutral	0.105
SLC26A4	O43511-1.1	L65D	Neutral	0.378
SLC26A4	O43511-1.1	L65E	Neutral	0.418
SLC26A4	O43511-1.1	L65F	Neutral	0.201
SLC26A4	O43511-1.1	L65G	Neutral	0.105
SLC26A4	O43511-1.1	L65H	Pathogenic	0.592
SLC26A4	O43511-1.1	L65I	Neutral	0.093
SLC26A4	O43511-1.1	L65K	Neutral	0.272
SLC26A4	O43511-1.1	L65M	Neutral	0.081
SLC26A4	O43511-1.1	L65N	Neutral	0.288
SLC26A4	O43511-1.1	L65P	Neutral	0.339
SLC26A4	O43511-1.1	L65Q	Neutral	0.345
SLC26A4	O43511-1.1	L65R	Neutral	0.171
SLC26A4	O43511-1.1	L65S	Neutral	0.081
SLC26A4	O43511-1.1	L65T	Neutral	0.109
SLC26A4	O43511-1.1	L65V	Neutral	0.07
SLC26A4	O43511-1.1	L65W	Neutral	0.194
SLC26A4	O43511-1.1	L65Y	Neutral	0.231
SLC26A4	O43511-1.1	K66A	Neutral	0.156
SLC26A4	O43511-1.1	K66C	Pathogenic	0.575
SLC26A4	O43511-1.1	K66D	Neutral	0.452
SLC26A4	O43511-1.1	K66E	Neutral	0.305
SLC26A4	O43511-1.1	K66F	Pathogenic	0.901
SLC26A4	O43511-1.1	K66G	Neutral	0.15
SLC26A4	O43511-1.1	K66H	Pathogenic	0.664
SLC26A4	O43511-1.1	K66I	Pathogenic	0.846
SLC26A4	O43511-1.1	K66L	Pathogenic	0.739
SLC26A4	O43511-1.1	K66M	Pathogenic	0.629
SLC26A4	O43511-1.1	K66N	Neutral	0.326
SLC26A4	O43511-1.1	K66P	Neutral	0.308
SLC26A4	O43511-1.1	K66Q	Neutral	0.319
SLC26A4	O43511-1.1	K66R	Neutral	0.309
SLC26A4	O43511-1.1	K66S	Neutral	0.121
SLC26A4	O43511-1.1	K66T	Neutral	0.378
SLC26A4	O43511-1.1	K66V	Pathogenic	0.592
SLC26A4	O43511-1.1	K66W	Pathogenic	0.682
SLC26A4	O43511-1.1	K66Y	Pathogenic	0.826
SLC26A4	O43511-1.1	T67A	Neutral	0.276
SLC26A4	O43511-1.1	T67C	Pathogenic	0.583
SLC26A4	O43511-1.1	T67D	Pathogenic	0.609
SLC26A4	O43511-1.1	T67E	Neutral	0.466
SLC26A4	O43511-1.1	T67F	Neutral	0.297
SLC26A4	O43511-1.1	T67G	Neutral	0.377
SLC26A4	O43511-1.1	T67H	Pathogenic	0.611
SLC26A4	O43511-1.1	T67I	Neutral	0.256
SLC26A4	O43511-1.1	T67K	Neutral	0.19
SLC26A4	O43511-1.1	T67L	Neutral	0.264
SLC26A4	O43511-1.1	T67M	Neutral	0.3
SLC26A4	O43511-1.1	T67N	Neutral	0.442
SLC26A4	O43511-1.1	T67P	Pathogenic	0.649
SLC26A4	O43511-1.1	T67Q	Neutral	0.45
SLC26A4	O43511-1.1	T67R	Neutral	0.115
SLC26A4	O43511-1.1	T67S	Neutral	0.185
SLC26A4	O43511-1.1	T67V	Neutral	0.336
SLC26A4	O43511-1.1	T67W	Neutral	0.091
SLC26A4	O43511-1.1	T67Y	Neutral	0.308
SLC26A4	O43511-1.1	L68A	Pathogenic	0.53
SLC26A4	O43511-1.1	L68C	Pathogenic	0.775
SLC26A4	O43511-1.1	L68D	Pathogenic	0.947
SLC26A4	O43511-1.1	L68E	Pathogenic	0.955
SLC26A4	O43511-1.1	L68F	Pathogenic	0.881
SLC26A4	O43511-1.1	L68G	Pathogenic	0.775
SLC26A4	O43511-1.1	L68H	Pathogenic	0.977
SLC26A4	O43511-1.1	L68I	Pathogenic	0.75
SLC26A4	O43511-1.1	L68K	Pathogenic	0.916
SLC26A4	O43511-1.1	L68M	Pathogenic	0.722
SLC26A4	O43511-1.1	L68N	Pathogenic	0.922
SLC26A4	O43511-1.1	L68P	Pathogenic	0.938
SLC26A4	O43511-1.1	L68Q	Pathogenic	0.939
SLC26A4	O43511-1.1	L68R	Pathogenic	0.858
SLC26A4	O43511-1.1	L68S	Pathogenic	0.722
SLC26A4	O43511-1.1	L68T	Pathogenic	0.781
SLC26A4	O43511-1.1	L68V	Pathogenic	0.688
SLC26A4	O43511-1.1	L68W	Pathogenic	0.876
SLC26A4	O43511-1.1	L68Y	Pathogenic	0.898
SLC26A4	O43511-1.1	V69A	Neutral	0.004
SLC26A4	O43511-1.1	V69C	Neutral	0.025
SLC26A4	O43511-1.1	V69D	Neutral	0.061
SLC26A4	O43511-1.1	V69E	Neutral	0.051
SLC26A4	O43511-1.1	V69F	Neutral	0.013
SLC26A4	O43511-1.1	V69G	Neutral	0.012
SLC26A4	O43511-1.1	V69H	Neutral	0.088
SLC26A4	O43511-1.1	V69I	Neutral	0.001
SLC26A4	O43511-1.1	V69K	Neutral	0.014
SLC26A4	O43511-1.1	V69L	Neutral	0.006
SLC26A4	O43511-1.1	V69M	Neutral	0.007
SLC26A4	O43511-1.1	V69N	Neutral	0.081
SLC26A4	O43511-1.1	V69P	Neutral	0.052
SLC26A4	O43511-1.1	V69Q	Neutral	0.048
SLC26A4	O43511-1.1	V69R	Neutral	0.016
SLC26A4	O43511-1.1	V69S	Neutral	0.019
SLC26A4	O43511-1.1	V69T	Neutral	0.013
SLC26A4	O43511-1.1	V69W	Neutral	0.013
SLC26A4	O43511-1.1	V69Y	Neutral	0.012
SLC26A4	O43511-1.1	P70A	Pathogenic	0.998
SLC26A4	O43511-1.1	P70C	Pathogenic	1.0
SLC26A4	O43511-1.1	P70D	Pathogenic	0.999
SLC26A4	O43511-1.1	P70E	Pathogenic	0.998
SLC26A4	O43511-1.1	P70F	Pathogenic	0.999
SLC26A4	O43511-1.1	P70G	Pathogenic	0.998
SLC26A4	O43511-1.1	P70H	Pathogenic	0.999
SLC26A4	O43511-1.1	P70I	Pathogenic	0.999
SLC26A4	O43511-1.1	P70K	Pathogenic	0.992
SLC26A4	O43511-1.1	P70L	Pathogenic	0.999
SLC26A4	O43511-1.1	P70M	Pathogenic	0.998
SLC26A4	O43511-1.1	P70N	Pathogenic	0.999
SLC26A4	O43511-1.1	P70Q	Pathogenic	0.998
SLC26A4	O43511-1.1	P70R	Pathogenic	0.993
SLC26A4	O43511-1.1	P70S	Pathogenic	0.998
SLC26A4	O43511-1.1	P70T	Pathogenic	0.999
SLC26A4	O43511-1.1	P70V	Pathogenic	0.999
SLC26A4	O43511-1.1	P70W	Pathogenic	0.997
SLC26A4	O43511-1.1	P70Y	Pathogenic	0.998
SLC26A4	O43511-1.1	I71A	Pathogenic	0.707
SLC26A4	O43511-1.1	I71C	Pathogenic	0.88
SLC26A4	O43511-1.1	I71D	Pathogenic	0.95
SLC26A4	O43511-1.1	I71E	Pathogenic	0.978
SLC26A4	O43511-1.1	I71F	Pathogenic	0.944
SLC26A4	O43511-1.1	I71G	Pathogenic	0.88
SLC26A4	O43511-1.1	I71H	Pathogenic	0.989
SLC26A4	O43511-1.1	I71K	Pathogenic	0.979
SLC26A4	O43511-1.1	I71L	Pathogenic	0.869
SLC26A4	O43511-1.1	I71M	Pathogenic	0.918
SLC26A4	O43511-1.1	I71N	Pathogenic	0.962
SLC26A4	O43511-1.1	I71P	Pathogenic	0.97
SLC26A4	O43511-1.1	I71Q	Pathogenic	0.985
SLC26A4	O43511-1.1	I71R	Pathogenic	0.963
SLC26A4	O43511-1.1	I71S	Pathogenic	0.847
SLC26A4	O43511-1.1	I71T	Pathogenic	0.884
SLC26A4	O43511-1.1	I71V	Pathogenic	0.538
SLC26A4	O43511-1.1	I71W	Pathogenic	0.97
SLC26A4	O43511-1.1	I71Y	Pathogenic	0.95
SLC26A4	O43511-1.1	L72A	Neutral	0.108
SLC26A4	O43511-1.1	L72C	Neutral	0.271
SLC26A4	O43511-1.1	L72D	Pathogenic	0.657
SLC26A4	O43511-1.1	L72E	Pathogenic	0.694
SLC26A4	O43511-1.1	L72F	Neutral	0.443
SLC26A4	O43511-1.1	L72G	Neutral	0.27
SLC26A4	O43511-1.1	L72H	Pathogenic	0.821
SLC26A4	O43511-1.1	L72I	Neutral	0.244
SLC26A4	O43511-1.1	L72K	Pathogenic	0.541
SLC26A4	O43511-1.1	L72M	Neutral	0.219
SLC26A4	O43511-1.1	L72N	Pathogenic	0.561
SLC26A4	O43511-1.1	L72P	Pathogenic	0.618
SLC26A4	O43511-1.1	L72Q	Pathogenic	0.624
SLC26A4	O43511-1.1	L72R	Neutral	0.395
SLC26A4	O43511-1.1	L72S	Neutral	0.219
SLC26A4	O43511-1.1	L72T	Neutral	0.278
SLC26A4	O43511-1.1	L72V	Neutral	0.192
SLC26A4	O43511-1.1	L72W	Neutral	0.432
SLC26A4	O43511-1.1	L72Y	Neutral	0.487
SLC26A4	O43511-1.1	E73A	Neutral	0.116
SLC26A4	O43511-1.1	E73C	Pathogenic	0.659
SLC26A4	O43511-1.1	E73D	Neutral	0.061
SLC26A4	O43511-1.1	E73F	Neutral	0.382
SLC26A4	O43511-1.1	E73G	Neutral	0.112
SLC26A4	O43511-1.1	E73H	Neutral	0.237
SLC26A4	O43511-1.1	E73I	Pathogenic	0.502
SLC26A4	O43511-1.1	E73K	Neutral	0.078
SLC26A4	O43511-1.1	E73L	Pathogenic	0.512
SLC26A4	O43511-1.1	E73M	Neutral	0.385
SLC26A4	O43511-1.1	E73N	Neutral	0.256
SLC26A4	O43511-1.1	E73P	Neutral	0.241
SLC26A4	O43511-1.1	E73Q	Neutral	0.095
SLC26A4	O43511-1.1	E73R	Neutral	0.086
SLC26A4	O43511-1.1	E73S	Neutral	0.089
SLC26A4	O43511-1.1	E73T	Neutral	0.302
SLC26A4	O43511-1.1	E73V	Pathogenic	0.508
SLC26A4	O43511-1.1	E73W	Neutral	0.127
SLC26A4	O43511-1.1	E73Y	Neutral	0.244
SLC26A4	O43511-1.1	W74A	Pathogenic	0.999
SLC26A4	O43511-1.1	W74C	Pathogenic	0.999
SLC26A4	O43511-1.1	W74D	Pathogenic	1.0
SLC26A4	O43511-1.1	W74E	Pathogenic	1.0
SLC26A4	O43511-1.1	W74F	Pathogenic	1.0
SLC26A4	O43511-1.1	W74G	Pathogenic	0.995
SLC26A4	O43511-1.1	W74H	Pathogenic	1.0
SLC26A4	O43511-1.1	W74I	Pathogenic	1.0
SLC26A4	O43511-1.1	W74K	Pathogenic	1.0
SLC26A4	O43511-1.1	W74L	Pathogenic	1.0
SLC26A4	O43511-1.1	W74M	Pathogenic	1.0
SLC26A4	O43511-1.1	W74N	Pathogenic	1.0
SLC26A4	O43511-1.1	W74P	Pathogenic	1.0
SLC26A4	O43511-1.1	W74Q	Pathogenic	1.0
SLC26A4	O43511-1.1	W74R	Pathogenic	1.0
SLC26A4	O43511-1.1	W74S	Pathogenic	0.999
SLC26A4	O43511-1.1	W74T	Pathogenic	0.999
SLC26A4	O43511-1.1	W74V	Pathogenic	1.0
SLC26A4	O43511-1.1	W74Y	Pathogenic	0.999
SLC26A4	O43511-1.1	L75A	Pathogenic	0.825
SLC26A4	O43511-1.1	L75C	Pathogenic	0.935
SLC26A4	O43511-1.1	L75D	Pathogenic	0.987
SLC26A4	O43511-1.1	L75E	Pathogenic	0.989
SLC26A4	O43511-1.1	L75F	Pathogenic	0.969
SLC26A4	O43511-1.1	L75G	Pathogenic	0.935
SLC26A4	O43511-1.1	L75H	Pathogenic	0.994
SLC26A4	O43511-1.1	L75I	Pathogenic	0.926
SLC26A4	O43511-1.1	L75K	Pathogenic	0.979
SLC26A4	O43511-1.1	L75M	Pathogenic	0.916
SLC26A4	O43511-1.1	L75N	Pathogenic	0.98
SLC26A4	O43511-1.1	L75P	Pathogenic	0.984
SLC26A4	O43511-1.1	L75Q	Pathogenic	0.985
SLC26A4	O43511-1.1	L75R	Pathogenic	0.962
SLC26A4	O43511-1.1	L75S	Pathogenic	0.916
SLC26A4	O43511-1.1	L75T	Pathogenic	0.937
SLC26A4	O43511-1.1	L75V	Pathogenic	0.902
SLC26A4	O43511-1.1	L75W	Pathogenic	0.967
SLC26A4	O43511-1.1	L75Y	Pathogenic	0.974
SLC26A4	O43511-1.1	P76A	Pathogenic	0.992
SLC26A4	O43511-1.1	P76C	Pathogenic	0.999
SLC26A4	O43511-1.1	P76D	Pathogenic	0.996
SLC26A4	O43511-1.1	P76E	Pathogenic	0.991
SLC26A4	O43511-1.1	P76F	Pathogenic	0.997
SLC26A4	O43511-1.1	P76G	Pathogenic	0.99
SLC26A4	O43511-1.1	P76H	Pathogenic	0.995
SLC26A4	O43511-1.1	P76I	Pathogenic	0.996
SLC26A4	O43511-1.1	P76K	Pathogenic	0.967
SLC26A4	O43511-1.1	P76L	Pathogenic	0.996
SLC26A4	O43511-1.1	P76M	Pathogenic	0.994
SLC26A4	O43511-1.1	P76N	Pathogenic	0.997
SLC26A4	O43511-1.1	P76Q	Pathogenic	0.99
SLC26A4	O43511-1.1	P76R	Pathogenic	0.97
SLC26A4	O43511-1.1	P76S	Pathogenic	0.993
SLC26A4	O43511-1.1	P76T	Pathogenic	0.997
SLC26A4	O43511-1.1	P76V	Pathogenic	0.997
SLC26A4	O43511-1.1	P76W	Pathogenic	0.986
SLC26A4	O43511-1.1	P76Y	Pathogenic	0.994
SLC26A4	O43511-1.1	K77A	Neutral	0.025
SLC26A4	O43511-1.1	K77C	Neutral	0.16
SLC26A4	O43511-1.1	K77D	Neutral	0.104
SLC26A4	O43511-1.1	K77E	Neutral	0.058
SLC26A4	O43511-1.1	K77F	Pathogenic	0.561
SLC26A4	O43511-1.1	K77G	Neutral	0.024
SLC26A4	O43511-1.1	K77H	Neutral	0.218
SLC26A4	O43511-1.1	K77I	Neutral	0.436
SLC26A4	O43511-1.1	K77L	Neutral	0.286
SLC26A4	O43511-1.1	K77M	Neutral	0.193
SLC26A4	O43511-1.1	K77N	Neutral	0.064
SLC26A4	O43511-1.1	K77P	Neutral	0.059
SLC26A4	O43511-1.1	K77Q	Neutral	0.062
SLC26A4	O43511-1.1	K77R	Neutral	0.059
SLC26A4	O43511-1.1	K77S	Neutral	0.019
SLC26A4	O43511-1.1	K77T	Neutral	0.079
SLC26A4	O43511-1.1	K77V	Neutral	0.17
SLC26A4	O43511-1.1	K77W	Neutral	0.232
SLC26A4	O43511-1.1	K77Y	Neutral	0.4
SLC26A4	O43511-1.1	Y78A	Pathogenic	0.994
SLC26A4	O43511-1.1	Y78C	Pathogenic	0.998
SLC26A4	O43511-1.1	Y78D	Pathogenic	0.999
SLC26A4	O43511-1.1	Y78E	Pathogenic	0.999
SLC26A4	O43511-1.1	Y78F	Pathogenic	0.991
SLC26A4	O43511-1.1	Y78G	Pathogenic	0.992
SLC26A4	O43511-1.1	Y78H	Pathogenic	0.99
SLC26A4	O43511-1.1	Y78I	Pathogenic	0.999
SLC26A4	O43511-1.1	Y78K	Pathogenic	1.0
SLC26A4	O43511-1.1	Y78L	Pathogenic	0.999
SLC26A4	O43511-1.1	Y78M	Pathogenic	0.999
SLC26A4	O43511-1.1	Y78N	Pathogenic	0.998
SLC26A4	O43511-1.1	Y78P	Pathogenic	0.999
SLC26A4	O43511-1.1	Y78Q	Pathogenic	0.998
SLC26A4	O43511-1.1	Y78R	Pathogenic	1.0
SLC26A4	O43511-1.1	Y78S	Pathogenic	0.995
SLC26A4	O43511-1.1	Y78T	Pathogenic	0.998
SLC26A4	O43511-1.1	Y78V	Pathogenic	0.998
SLC26A4	O43511-1.1	Y78W	Pathogenic	0.989
SLC26A4	O43511-1.1	R79A	Pathogenic	0.748
SLC26A4	O43511-1.1	R79C	Pathogenic	0.956
SLC26A4	O43511-1.1	R79D	Pathogenic	0.964
SLC26A4	O43511-1.1	R79E	Pathogenic	0.934
SLC26A4	O43511-1.1	R79F	Pathogenic	0.993
SLC26A4	O43511-1.1	R79G	Pathogenic	0.74
SLC26A4	O43511-1.1	R79H	Pathogenic	0.941
SLC26A4	O43511-1.1	R79I	Pathogenic	0.989
SLC26A4	O43511-1.1	R79K	Pathogenic	0.929
SLC26A4	O43511-1.1	R79L	Pathogenic	0.979
SLC26A4	O43511-1.1	R79M	Pathogenic	0.965
SLC26A4	O43511-1.1	R79N	Pathogenic	0.886
SLC26A4	O43511-1.1	R79P	Pathogenic	0.935
SLC26A4	O43511-1.1	R79Q	Pathogenic	0.883
SLC26A4	O43511-1.1	R79S	Pathogenic	0.816
SLC26A4	O43511-1.1	R79T	Pathogenic	0.907
SLC26A4	O43511-1.1	R79V	Pathogenic	0.979
SLC26A4	O43511-1.1	R79W	Pathogenic	0.991
SLC26A4	O43511-1.1	R79Y	Pathogenic	0.992
SLC26A4	O43511-1.1	V80A	Neutral	0.068
SLC26A4	O43511-1.1	V80C	Neutral	0.309
SLC26A4	O43511-1.1	V80D	Pathogenic	0.536
SLC26A4	O43511-1.1	V80E	Neutral	0.487
SLC26A4	O43511-1.1	V80F	Neutral	0.193
SLC26A4	O43511-1.1	V80G	Neutral	0.182
SLC26A4	O43511-1.1	V80H	Pathogenic	0.631
SLC26A4	O43511-1.1	V80I	Neutral	0.023
SLC26A4	O43511-1.1	V80K	Neutral	0.204
SLC26A4	O43511-1.1	V80L	Neutral	0.092
SLC26A4	O43511-1.1	V80M	Neutral	0.108
SLC26A4	O43511-1.1	V80N	Pathogenic	0.607
SLC26A4	O43511-1.1	V80P	Neutral	0.493
SLC26A4	O43511-1.1	V80Q	Neutral	0.471
SLC26A4	O43511-1.1	V80R	Neutral	0.221
SLC26A4	O43511-1.1	V80S	Neutral	0.253
SLC26A4	O43511-1.1	V80T	Neutral	0.188
SLC26A4	O43511-1.1	V80W	Neutral	0.186
SLC26A4	O43511-1.1	V80Y	Neutral	0.171
SLC26A4	O43511-1.1	K81A	Pathogenic	0.859
SLC26A4	O43511-1.1	K81C	Pathogenic	0.978
SLC26A4	O43511-1.1	K81D	Pathogenic	0.965
SLC26A4	O43511-1.1	K81E	Pathogenic	0.935
SLC26A4	O43511-1.1	K81F	Pathogenic	0.997
SLC26A4	O43511-1.1	K81G	Pathogenic	0.854
SLC26A4	O43511-1.1	K81H	Pathogenic	0.985
SLC26A4	O43511-1.1	K81I	Pathogenic	0.994
SLC26A4	O43511-1.1	K81L	Pathogenic	0.989
SLC26A4	O43511-1.1	K81M	Pathogenic	0.982
SLC26A4	O43511-1.1	K81N	Pathogenic	0.941
SLC26A4	O43511-1.1	K81P	Pathogenic	0.936
SLC26A4	O43511-1.1	K81Q	Pathogenic	0.939
SLC26A4	O43511-1.1	K81R	Pathogenic	0.936
SLC26A4	O43511-1.1	K81S	Pathogenic	0.819
SLC26A4	O43511-1.1	K81T	Pathogenic	0.952
SLC26A4	O43511-1.1	K81V	Pathogenic	0.98
SLC26A4	O43511-1.1	K81W	Pathogenic	0.986
SLC26A4	O43511-1.1	K81Y	Pathogenic	0.994
SLC26A4	O43511-1.1	E82A	Pathogenic	0.977
SLC26A4	O43511-1.1	E82C	Pathogenic	0.998
SLC26A4	O43511-1.1	E82D	Pathogenic	0.955
SLC26A4	O43511-1.1	E82F	Pathogenic	0.995
SLC26A4	O43511-1.1	E82G	Pathogenic	0.976
SLC26A4	O43511-1.1	E82H	Pathogenic	0.99
SLC26A4	O43511-1.1	E82I	Pathogenic	0.997
SLC26A4	O43511-1.1	E82K	Pathogenic	0.965
SLC26A4	O43511-1.1	E82L	Pathogenic	0.997
SLC26A4	O43511-1.1	E82M	Pathogenic	0.995
SLC26A4	O43511-1.1	E82N	Pathogenic	0.991
SLC26A4	O43511-1.1	E82P	Pathogenic	0.99
SLC26A4	O43511-1.1	E82Q	Pathogenic	0.971
SLC26A4	O43511-1.1	E82R	Pathogenic	0.968
SLC26A4	O43511-1.1	E82S	Pathogenic	0.969
SLC26A4	O43511-1.1	E82T	Pathogenic	0.993
SLC26A4	O43511-1.1	E82V	Pathogenic	0.997
SLC26A4	O43511-1.1	E82W	Pathogenic	0.979
SLC26A4	O43511-1.1	E82Y	Pathogenic	0.99
SLC26A4	O43511-1.1	W83A	Pathogenic	0.997
SLC26A4	O43511-1.1	W83C	Pathogenic	0.998
SLC26A4	O43511-1.1	W83D	Pathogenic	0.999
SLC26A4	O43511-1.1	W83E	Pathogenic	0.999
SLC26A4	O43511-1.1	W83F	Pathogenic	0.999
SLC26A4	O43511-1.1	W83G	Pathogenic	0.987
SLC26A4	O43511-1.1	W83H	Pathogenic	0.999
SLC26A4	O43511-1.1	W83I	Pathogenic	1.0
SLC26A4	O43511-1.1	W83K	Pathogenic	1.0
SLC26A4	O43511-1.1	W83L	Pathogenic	1.0
SLC26A4	O43511-1.1	W83M	Pathogenic	0.999
SLC26A4	O43511-1.1	W83N	Pathogenic	1.0
SLC26A4	O43511-1.1	W83P	Pathogenic	1.0
SLC26A4	O43511-1.1	W83Q	Pathogenic	0.999
SLC26A4	O43511-1.1	W83R	Pathogenic	1.0
SLC26A4	O43511-1.1	W83S	Pathogenic	0.998
SLC26A4	O43511-1.1	W83T	Pathogenic	0.998
SLC26A4	O43511-1.1	W83V	Pathogenic	1.0
SLC26A4	O43511-1.1	W83Y	Pathogenic	0.998
SLC26A4	O43511-1.1	L84A	Pathogenic	0.64
SLC26A4	O43511-1.1	L84C	Pathogenic	0.844
SLC26A4	O43511-1.1	L84D	Pathogenic	0.966
SLC26A4	O43511-1.1	L84E	Pathogenic	0.971
SLC26A4	O43511-1.1	L84F	Pathogenic	0.921
SLC26A4	O43511-1.1	L84G	Pathogenic	0.844
SLC26A4	O43511-1.1	L84H	Pathogenic	0.985
SLC26A4	O43511-1.1	L84I	Pathogenic	0.825
SLC26A4	O43511-1.1	L84K	Pathogenic	0.945
SLC26A4	O43511-1.1	L84M	Pathogenic	0.804
SLC26A4	O43511-1.1	L84N	Pathogenic	0.949
SLC26A4	O43511-1.1	L84P	Pathogenic	0.959
SLC26A4	O43511-1.1	L84Q	Pathogenic	0.96
SLC26A4	O43511-1.1	L84R	Pathogenic	0.905
SLC26A4	O43511-1.1	L84S	Pathogenic	0.804
SLC26A4	O43511-1.1	L84T	Pathogenic	0.849
SLC26A4	O43511-1.1	L84V	Pathogenic	0.776
SLC26A4	O43511-1.1	L84W	Pathogenic	0.917
SLC26A4	O43511-1.1	L84Y	Pathogenic	0.933
SLC26A4	O43511-1.1	L85A	Pathogenic	0.739
SLC26A4	O43511-1.1	L85C	Pathogenic	0.897
SLC26A4	O43511-1.1	L85D	Pathogenic	0.978
SLC26A4	O43511-1.1	L85E	Pathogenic	0.981
SLC26A4	O43511-1.1	L85F	Pathogenic	0.949
SLC26A4	O43511-1.1	L85G	Pathogenic	0.896
SLC26A4	O43511-1.1	L85H	Pathogenic	0.991
SLC26A4	O43511-1.1	L85I	Pathogenic	0.883
SLC26A4	O43511-1.1	L85K	Pathogenic	0.965
SLC26A4	O43511-1.1	L85M	Pathogenic	0.867
SLC26A4	O43511-1.1	L85N	Pathogenic	0.968
SLC26A4	O43511-1.1	L85P	Pathogenic	0.974
SLC26A4	O43511-1.1	L85Q	Pathogenic	0.975
SLC26A4	O43511-1.1	L85R	Pathogenic	0.938
SLC26A4	O43511-1.1	L85S	Pathogenic	0.867
SLC26A4	O43511-1.1	L85T	Pathogenic	0.9
SLC26A4	O43511-1.1	L85V	Pathogenic	0.847
SLC26A4	O43511-1.1	L85W	Pathogenic	0.947
SLC26A4	O43511-1.1	L85Y	Pathogenic	0.957
SLC26A4	O43511-1.1	S86A	Pathogenic	0.948
SLC26A4	O43511-1.1	S86C	Pathogenic	0.977
SLC26A4	O43511-1.1	S86D	Pathogenic	0.949
SLC26A4	O43511-1.1	S86E	Pathogenic	0.896
SLC26A4	O43511-1.1	S86F	Pathogenic	0.87
SLC26A4	O43511-1.1	S86G	Pathogenic	0.946
SLC26A4	O43511-1.1	S86H	Pathogenic	0.932
SLC26A4	O43511-1.1	S86I	Pathogenic	0.916
SLC26A4	O43511-1.1	S86K	Pathogenic	0.699
SLC26A4	O43511-1.1	S86L	Pathogenic	0.919
SLC26A4	O43511-1.1	S86M	Pathogenic	0.872
SLC26A4	O43511-1.1	S86N	Pathogenic	0.887
SLC26A4	O43511-1.1	S86P	Pathogenic	0.975
SLC26A4	O43511-1.1	S86Q	Pathogenic	0.89
SLC26A4	O43511-1.1	S86R	Pathogenic	0.721
SLC26A4	O43511-1.1	S86T	Pathogenic	0.909
SLC26A4	O43511-1.1	S86V	Pathogenic	0.97
SLC26A4	O43511-1.1	S86W	Pathogenic	0.761
SLC26A4	O43511-1.1	S86Y	Pathogenic	0.876
SLC26A4	O43511-1.1	D87A	Pathogenic	0.998
SLC26A4	O43511-1.1	D87C	Pathogenic	1.0
SLC26A4	O43511-1.1	D87E	Pathogenic	0.986
SLC26A4	O43511-1.1	D87F	Pathogenic	0.997
SLC26A4	O43511-1.1	D87G	Pathogenic	0.993
SLC26A4	O43511-1.1	D87H	Pathogenic	0.997
SLC26A4	O43511-1.1	D87I	Pathogenic	0.998
SLC26A4	O43511-1.1	D87K	Pathogenic	0.994
SLC26A4	O43511-1.1	D87L	Pathogenic	0.999
SLC26A4	O43511-1.1	D87M	Pathogenic	0.998
SLC26A4	O43511-1.1	D87N	Pathogenic	0.996
SLC26A4	O43511-1.1	D87P	Pathogenic	0.999
SLC26A4	O43511-1.1	D87Q	Pathogenic	0.995
SLC26A4	O43511-1.1	D87R	Pathogenic	0.995
SLC26A4	O43511-1.1	D87S	Pathogenic	0.996
SLC26A4	O43511-1.1	D87T	Pathogenic	0.999
SLC26A4	O43511-1.1	D87V	Pathogenic	0.999
SLC26A4	O43511-1.1	D87W	Pathogenic	0.993
SLC26A4	O43511-1.1	D87Y	Pathogenic	0.997
SLC26A4	O43511-1.1	V88A	Neutral	0.027
SLC26A4	O43511-1.1	V88C	Neutral	0.148
SLC26A4	O43511-1.1	V88D	Neutral	0.309
SLC26A4	O43511-1.1	V88E	Neutral	0.269
SLC26A4	O43511-1.1	V88F	Neutral	0.085
SLC26A4	O43511-1.1	V88G	Neutral	0.079
SLC26A4	O43511-1.1	V88H	Neutral	0.398
SLC26A4	O43511-1.1	V88I	Neutral	0.009
SLC26A4	O43511-1.1	V88K	Neutral	0.09
SLC26A4	O43511-1.1	V88L	Neutral	0.038
SLC26A4	O43511-1.1	V88M	Neutral	0.045
SLC26A4	O43511-1.1	V88N	Neutral	0.374
SLC26A4	O43511-1.1	V88P	Neutral	0.274
SLC26A4	O43511-1.1	V88Q	Neutral	0.256
SLC26A4	O43511-1.1	V88R	Neutral	0.099
SLC26A4	O43511-1.1	V88S	Neutral	0.116
SLC26A4	O43511-1.1	V88T	Neutral	0.082
SLC26A4	O43511-1.1	V88W	Neutral	0.081
SLC26A4	O43511-1.1	V88Y	Neutral	0.074
SLC26A4	O43511-1.1	I89A	Neutral	0.359
SLC26A4	O43511-1.1	I89C	Pathogenic	0.631
SLC26A4	O43511-1.1	I89D	Pathogenic	0.815
SLC26A4	O43511-1.1	I89E	Pathogenic	0.913
SLC26A4	O43511-1.1	I89F	Pathogenic	0.797
SLC26A4	O43511-1.1	I89G	Pathogenic	0.631
SLC26A4	O43511-1.1	I89H	Pathogenic	0.955
SLC26A4	O43511-1.1	I89K	Pathogenic	0.916
SLC26A4	O43511-1.1	I89L	Pathogenic	0.608
SLC26A4	O43511-1.1	I89M	Pathogenic	0.722
SLC26A4	O43511-1.1	I89N	Pathogenic	0.855
SLC26A4	O43511-1.1	I89P	Pathogenic	0.882
SLC26A4	O43511-1.1	I89Q	Pathogenic	0.939
SLC26A4	O43511-1.1	I89R	Pathogenic	0.858
SLC26A4	O43511-1.1	I89S	Pathogenic	0.564
SLC26A4	O43511-1.1	I89T	Pathogenic	0.64
SLC26A4	O43511-1.1	I89V	Neutral	0.213
SLC26A4	O43511-1.1	I89W	Pathogenic	0.884
SLC26A4	O43511-1.1	I89Y	Pathogenic	0.814
SLC26A4	O43511-1.1	S90A	Pathogenic	0.987
SLC26A4	O43511-1.1	S90C	Pathogenic	0.994
SLC26A4	O43511-1.1	S90D	Pathogenic	0.987
SLC26A4	O43511-1.1	S90E	Pathogenic	0.972
SLC26A4	O43511-1.1	S90F	Pathogenic	0.965
SLC26A4	O43511-1.1	S90G	Pathogenic	0.986
SLC26A4	O43511-1.1	S90H	Pathogenic	0.982
SLC26A4	O43511-1.1	S90I	Pathogenic	0.978
SLC26A4	O43511-1.1	S90K	Pathogenic	0.904
SLC26A4	O43511-1.1	S90L	Pathogenic	0.979
SLC26A4	O43511-1.1	S90M	Pathogenic	0.965
SLC26A4	O43511-1.1	S90N	Pathogenic	0.969
SLC26A4	O43511-1.1	S90P	Pathogenic	0.994
SLC26A4	O43511-1.1	S90Q	Pathogenic	0.97
SLC26A4	O43511-1.1	S90R	Pathogenic	0.913
SLC26A4	O43511-1.1	S90T	Pathogenic	0.976
SLC26A4	O43511-1.1	S90V	Pathogenic	0.992
SLC26A4	O43511-1.1	S90W	Pathogenic	0.928
SLC26A4	O43511-1.1	S90Y	Pathogenic	0.966
SLC26A4	O43511-1.1	G91A	Pathogenic	0.992
SLC26A4	O43511-1.1	G91C	Pathogenic	0.997
SLC26A4	O43511-1.1	G91D	Pathogenic	0.986
SLC26A4	O43511-1.1	G91E	Pathogenic	0.985
SLC26A4	O43511-1.1	G91F	Pathogenic	0.962
SLC26A4	O43511-1.1	G91H	Pathogenic	0.981
SLC26A4	O43511-1.1	G91I	Pathogenic	0.988
SLC26A4	O43511-1.1	G91K	Pathogenic	0.945
SLC26A4	O43511-1.1	G91L	Pathogenic	0.989
SLC26A4	O43511-1.1	G91M	Pathogenic	0.981
SLC26A4	O43511-1.1	G91N	Pathogenic	0.967
SLC26A4	O43511-1.1	G91P	Pathogenic	0.993
SLC26A4	O43511-1.1	G91Q	Pathogenic	0.984
SLC26A4	O43511-1.1	G91R	Pathogenic	0.905
SLC26A4	O43511-1.1	G91S	Pathogenic	0.99
SLC26A4	O43511-1.1	G91T	Pathogenic	0.994
SLC26A4	O43511-1.1	G91V	Pathogenic	0.992
SLC26A4	O43511-1.1	G91W	Pathogenic	0.751
SLC26A4	O43511-1.1	G91Y	Pathogenic	0.964
SLC26A4	O43511-1.1	V92A	Neutral	0.275
SLC26A4	O43511-1.1	V92C	Pathogenic	0.7
SLC26A4	O43511-1.1	V92D	Pathogenic	0.857
SLC26A4	O43511-1.1	V92E	Pathogenic	0.832
SLC26A4	O43511-1.1	V92F	Pathogenic	0.555
SLC26A4	O43511-1.1	V92G	Pathogenic	0.537
SLC26A4	O43511-1.1	V92H	Pathogenic	0.899
SLC26A4	O43511-1.1	V92I	Neutral	0.111
SLC26A4	O43511-1.1	V92K	Pathogenic	0.571
SLC26A4	O43511-1.1	V92L	Neutral	0.344
SLC26A4	O43511-1.1	V92M	Neutral	0.386
SLC26A4	O43511-1.1	V92N	Pathogenic	0.889
SLC26A4	O43511-1.1	V92P	Pathogenic	0.835
SLC26A4	O43511-1.1	V92Q	Pathogenic	0.822
SLC26A4	O43511-1.1	V92R	Pathogenic	0.597
SLC26A4	O43511-1.1	V92S	Pathogenic	0.638
SLC26A4	O43511-1.1	V92T	Pathogenic	0.546
SLC26A4	O43511-1.1	V92W	Pathogenic	0.543
SLC26A4	O43511-1.1	V92Y	Pathogenic	0.518
SLC26A4	O43511-1.1	S93A	Pathogenic	0.951
SLC26A4	O43511-1.1	S93C	Pathogenic	0.978
SLC26A4	O43511-1.1	S93D	Pathogenic	0.951
SLC26A4	O43511-1.1	S93E	Pathogenic	0.901
SLC26A4	O43511-1.1	S93F	Pathogenic	0.876
SLC26A4	O43511-1.1	S93G	Pathogenic	0.949
SLC26A4	O43511-1.1	S93H	Pathogenic	0.935
SLC26A4	O43511-1.1	S93I	Pathogenic	0.921
SLC26A4	O43511-1.1	S93K	Pathogenic	0.711
SLC26A4	O43511-1.1	S93L	Pathogenic	0.923
SLC26A4	O43511-1.1	S93M	Pathogenic	0.878
SLC26A4	O43511-1.1	S93N	Pathogenic	0.892
SLC26A4	O43511-1.1	S93P	Pathogenic	0.976
SLC26A4	O43511-1.1	S93Q	Pathogenic	0.895
SLC26A4	O43511-1.1	S93R	Pathogenic	0.732
SLC26A4	O43511-1.1	S93T	Pathogenic	0.913
SLC26A4	O43511-1.1	S93V	Pathogenic	0.972
SLC26A4	O43511-1.1	S93W	Pathogenic	0.771
SLC26A4	O43511-1.1	S93Y	Pathogenic	0.882
SLC26A4	O43511-1.1	T94A	Pathogenic	0.994
SLC26A4	O43511-1.1	T94C	Pathogenic	0.998
SLC26A4	O43511-1.1	T94D	Pathogenic	0.998
SLC26A4	O43511-1.1	T94E	Pathogenic	0.997
SLC26A4	O43511-1.1	T94F	Pathogenic	0.994
SLC26A4	O43511-1.1	T94G	Pathogenic	0.996
SLC26A4	O43511-1.1	T94H	Pathogenic	0.998
SLC26A4	O43511-1.1	T94I	Pathogenic	0.993
SLC26A4	O43511-1.1	T94K	Pathogenic	0.99
SLC26A4	O43511-1.1	T94L	Pathogenic	0.993
SLC26A4	O43511-1.1	T94M	Pathogenic	0.994
SLC26A4	O43511-1.1	T94N	Pathogenic	0.997
SLC26A4	O43511-1.1	T94P	Pathogenic	0.999
SLC26A4	O43511-1.1	T94Q	Pathogenic	0.997
SLC26A4	O43511-1.1	T94R	Pathogenic	0.982
SLC26A4	O43511-1.1	T94S	Pathogenic	0.99
SLC26A4	O43511-1.1	T94V	Pathogenic	0.995
SLC26A4	O43511-1.1	T94W	Pathogenic	0.977
SLC26A4	O43511-1.1	T94Y	Pathogenic	0.995
SLC26A4	O43511-1.1	G95A	Pathogenic	0.991
SLC26A4	O43511-1.1	G95C	Pathogenic	0.997
SLC26A4	O43511-1.1	G95D	Pathogenic	0.985
SLC26A4	O43511-1.1	G95E	Pathogenic	0.984
SLC26A4	O43511-1.1	G95F	Pathogenic	0.96
SLC26A4	O43511-1.1	G95H	Pathogenic	0.98
SLC26A4	O43511-1.1	G95I	Pathogenic	0.988
SLC26A4	O43511-1.1	G95K	Pathogenic	0.942
SLC26A4	O43511-1.1	G95L	Pathogenic	0.988
SLC26A4	O43511-1.1	G95M	Pathogenic	0.98
SLC26A4	O43511-1.1	G95N	Pathogenic	0.965
SLC26A4	O43511-1.1	G95P	Pathogenic	0.993
SLC26A4	O43511-1.1	G95Q	Pathogenic	0.983
SLC26A4	O43511-1.1	G95R	Pathogenic	0.901
SLC26A4	O43511-1.1	G95S	Pathogenic	0.99
SLC26A4	O43511-1.1	G95T	Pathogenic	0.993
SLC26A4	O43511-1.1	G95V	Pathogenic	0.992
SLC26A4	O43511-1.1	G95W	Pathogenic	0.74
SLC26A4	O43511-1.1	G95Y	Pathogenic	0.962
SLC26A4	O43511-1.1	L96A	Pathogenic	0.671
SLC26A4	O43511-1.1	L96C	Pathogenic	0.862
SLC26A4	O43511-1.1	L96D	Pathogenic	0.97
SLC26A4	O43511-1.1	L96E	Pathogenic	0.974
SLC26A4	O43511-1.1	L96F	Pathogenic	0.93
SLC26A4	O43511-1.1	L96G	Pathogenic	0.861
SLC26A4	O43511-1.1	L96H	Pathogenic	0.987
SLC26A4	O43511-1.1	L96I	Pathogenic	0.844
SLC26A4	O43511-1.1	L96K	Pathogenic	0.952
SLC26A4	O43511-1.1	L96M	Pathogenic	0.824
SLC26A4	O43511-1.1	L96N	Pathogenic	0.955
SLC26A4	O43511-1.1	L96P	Pathogenic	0.965
SLC26A4	O43511-1.1	L96Q	Pathogenic	0.965
SLC26A4	O43511-1.1	L96R	Pathogenic	0.916
SLC26A4	O43511-1.1	L96S	Pathogenic	0.824
SLC26A4	O43511-1.1	L96T	Pathogenic	0.866
SLC26A4	O43511-1.1	L96V	Pathogenic	0.799
SLC26A4	O43511-1.1	L96W	Pathogenic	0.927
SLC26A4	O43511-1.1	L96Y	Pathogenic	0.941
SLC26A4	O43511-1.1	V97A	Pathogenic	0.889
SLC26A4	O43511-1.1	V97C	Pathogenic	0.98
SLC26A4	O43511-1.1	V97D	Pathogenic	0.992
SLC26A4	O43511-1.1	V97E	Pathogenic	0.99
SLC26A4	O43511-1.1	V97F	Pathogenic	0.963
SLC26A4	O43511-1.1	V97G	Pathogenic	0.961
SLC26A4	O43511-1.1	V97H	Pathogenic	0.995
SLC26A4	O43511-1.1	V97I	Pathogenic	0.725
SLC26A4	O43511-1.1	V97K	Pathogenic	0.966
SLC26A4	O43511-1.1	V97L	Pathogenic	0.917
SLC26A4	O43511-1.1	V97M	Pathogenic	0.93
SLC26A4	O43511-1.1	V97N	Pathogenic	0.994
SLC26A4	O43511-1.1	V97P	Pathogenic	0.991
SLC26A4	O43511-1.1	V97Q	Pathogenic	0.99
SLC26A4	O43511-1.1	V97R	Pathogenic	0.969
SLC26A4	O43511-1.1	V97S	Pathogenic	0.974
SLC26A4	O43511-1.1	V97T	Pathogenic	0.962
SLC26A4	O43511-1.1	V97W	Pathogenic	0.962
SLC26A4	O43511-1.1	V97Y	Pathogenic	0.958
SLC26A4	O43511-1.1	A98C	Pathogenic	0.622
SLC26A4	O43511-1.1	A98D	Pathogenic	0.819
SLC26A4	O43511-1.1	A98E	Pathogenic	0.513
SLC26A4	O43511-1.1	A98F	Neutral	0.348
SLC26A4	O43511-1.1	A98G	Pathogenic	0.655
SLC26A4	O43511-1.1	A98H	Pathogenic	0.655
SLC26A4	O43511-1.1	A98I	Neutral	0.302
SLC26A4	O43511-1.1	A98K	Neutral	0.222
SLC26A4	O43511-1.1	A98L	Neutral	0.311
SLC26A4	O43511-1.1	A98M	Neutral	0.351
SLC26A4	O43511-1.1	A98N	Pathogenic	0.794
SLC26A4	O43511-1.1	A98P	Pathogenic	0.753
SLC26A4	O43511-1.1	A98Q	Neutral	0.497
SLC26A4	O43511-1.1	A98R	Neutral	0.136
SLC26A4	O43511-1.1	A98S	Pathogenic	0.626
SLC26A4	O43511-1.1	A98T	Pathogenic	0.604
SLC26A4	O43511-1.1	A98V	Neutral	0.389
SLC26A4	O43511-1.1	A98W	Neutral	0.202
SLC26A4	O43511-1.1	A98Y	Neutral	0.359
SLC26A4	O43511-1.1	T99A	Pathogenic	0.621
SLC26A4	O43511-1.1	T99C	Pathogenic	0.857
SLC26A4	O43511-1.1	T99D	Pathogenic	0.87
SLC26A4	O43511-1.1	T99E	Pathogenic	0.789
SLC26A4	O43511-1.1	T99F	Pathogenic	0.645
SLC26A4	O43511-1.1	T99G	Pathogenic	0.721
SLC26A4	O43511-1.1	T99H	Pathogenic	0.871
SLC26A4	O43511-1.1	T99I	Pathogenic	0.596
SLC26A4	O43511-1.1	T99K	Pathogenic	0.502
SLC26A4	O43511-1.1	T99L	Pathogenic	0.606
SLC26A4	O43511-1.1	T99M	Pathogenic	0.648
SLC26A4	O43511-1.1	T99N	Pathogenic	0.772
SLC26A4	O43511-1.1	T99P	Pathogenic	0.888
SLC26A4	O43511-1.1	T99Q	Pathogenic	0.778
SLC26A4	O43511-1.1	T99R	Neutral	0.358
SLC26A4	O43511-1.1	T99S	Neutral	0.493
SLC26A4	O43511-1.1	T99V	Pathogenic	0.685
SLC26A4	O43511-1.1	T99W	Neutral	0.3
SLC26A4	O43511-1.1	T99Y	Pathogenic	0.656
SLC26A4	O43511-1.1	L100A	Pathogenic	0.819
SLC26A4	O43511-1.1	L100C	Pathogenic	0.933
SLC26A4	O43511-1.1	L100D	Pathogenic	0.986
SLC26A4	O43511-1.1	L100E	Pathogenic	0.988
SLC26A4	O43511-1.1	L100F	Pathogenic	0.967
SLC26A4	O43511-1.1	L100G	Pathogenic	0.933
SLC26A4	O43511-1.1	L100H	Pathogenic	0.994
SLC26A4	O43511-1.1	L100I	Pathogenic	0.923
SLC26A4	O43511-1.1	L100K	Pathogenic	0.978
SLC26A4	O43511-1.1	L100M	Pathogenic	0.913
SLC26A4	O43511-1.1	L100N	Pathogenic	0.979
SLC26A4	O43511-1.1	L100P	Pathogenic	0.984
SLC26A4	O43511-1.1	L100Q	Pathogenic	0.984
SLC26A4	O43511-1.1	L100R	Pathogenic	0.961
SLC26A4	O43511-1.1	L100S	Pathogenic	0.913
SLC26A4	O43511-1.1	L100T	Pathogenic	0.935
SLC26A4	O43511-1.1	L100V	Pathogenic	0.899
SLC26A4	O43511-1.1	L100W	Pathogenic	0.966
SLC26A4	O43511-1.1	L100Y	Pathogenic	0.973
SLC26A4	O43511-1.1	Q101A	Pathogenic	0.995
SLC26A4	O43511-1.1	Q101C	Pathogenic	0.999
SLC26A4	O43511-1.1	Q101D	Pathogenic	0.997
SLC26A4	O43511-1.1	Q101E	Pathogenic	0.994
SLC26A4	O43511-1.1	Q101F	Pathogenic	0.999
SLC26A4	O43511-1.1	Q101G	Pathogenic	0.995
SLC26A4	O43511-1.1	Q101H	Pathogenic	0.999
SLC26A4	O43511-1.1	Q101I	Pathogenic	1.0
SLC26A4	O43511-1.1	Q101K	Pathogenic	0.993
SLC26A4	O43511-1.1	Q101L	Pathogenic	0.999
SLC26A4	O43511-1.1	Q101M	Pathogenic	0.997
SLC26A4	O43511-1.1	Q101N	Pathogenic	0.997
SLC26A4	O43511-1.1	Q101P	Pathogenic	0.998
SLC26A4	O43511-1.1	Q101R	Pathogenic	0.988
SLC26A4	O43511-1.1	Q101S	Pathogenic	0.993
SLC26A4	O43511-1.1	Q101T	Pathogenic	0.998
SLC26A4	O43511-1.1	Q101V	Pathogenic	0.999
SLC26A4	O43511-1.1	Q101W	Pathogenic	0.994
SLC26A4	O43511-1.1	Q101Y	Pathogenic	0.997
SLC26A4	O43511-1.1	G102A	Pathogenic	0.993
SLC26A4	O43511-1.1	G102C	Pathogenic	0.997
SLC26A4	O43511-1.1	G102D	Pathogenic	0.988
SLC26A4	O43511-1.1	G102E	Pathogenic	0.987
SLC26A4	O43511-1.1	G102F	Pathogenic	0.968
SLC26A4	O43511-1.1	G102H	Pathogenic	0.984
SLC26A4	O43511-1.1	G102I	Pathogenic	0.99
SLC26A4	O43511-1.1	G102K	Pathogenic	0.953
SLC26A4	O43511-1.1	G102L	Pathogenic	0.99
SLC26A4	O43511-1.1	G102M	Pathogenic	0.984
SLC26A4	O43511-1.1	G102N	Pathogenic	0.971
SLC26A4	O43511-1.1	G102P	Pathogenic	0.994
SLC26A4	O43511-1.1	G102Q	Pathogenic	0.986
SLC26A4	O43511-1.1	G102R	Pathogenic	0.918
SLC26A4	O43511-1.1	G102S	Pathogenic	0.992
SLC26A4	O43511-1.1	G102T	Pathogenic	0.994
SLC26A4	O43511-1.1	G102V	Pathogenic	0.993
SLC26A4	O43511-1.1	G102W	Pathogenic	0.778
SLC26A4	O43511-1.1	G102Y	Pathogenic	0.969
SLC26A4	O43511-1.1	M103A	Pathogenic	0.833
SLC26A4	O43511-1.1	M103C	Pathogenic	0.938
SLC26A4	O43511-1.1	M103D	Pathogenic	0.975
SLC26A4	O43511-1.1	M103E	Pathogenic	0.979
SLC26A4	O43511-1.1	M103F	Pathogenic	0.958
SLC26A4	O43511-1.1	M103G	Pathogenic	0.883
SLC26A4	O43511-1.1	M103H	Pathogenic	0.989
SLC26A4	O43511-1.1	M103I	Pathogenic	0.949
SLC26A4	O43511-1.1	M103K	Pathogenic	0.96
SLC26A4	O43511-1.1	M103L	Pathogenic	0.906
SLC26A4	O43511-1.1	M103N	Pathogenic	0.963
SLC26A4	O43511-1.1	M103P	Pathogenic	0.971
SLC26A4	O43511-1.1	M103Q	Pathogenic	0.944
SLC26A4	O43511-1.1	M103R	Pathogenic	0.93
SLC26A4	O43511-1.1	M103S	Pathogenic	0.851
SLC26A4	O43511-1.1	M103T	Pathogenic	0.94
SLC26A4	O43511-1.1	M103V	Pathogenic	0.907
SLC26A4	O43511-1.1	M103W	Pathogenic	0.915
SLC26A4	O43511-1.1	M103Y	Pathogenic	0.975
SLC26A4	O43511-1.1	A104C	Pathogenic	0.984
SLC26A4	O43511-1.1	A104D	Pathogenic	0.994
SLC26A4	O43511-1.1	A104E	Pathogenic	0.975
SLC26A4	O43511-1.1	A104F	Pathogenic	0.952
SLC26A4	O43511-1.1	A104G	Pathogenic	0.986
SLC26A4	O43511-1.1	A104H	Pathogenic	0.986
SLC26A4	O43511-1.1	A104I	Pathogenic	0.941
SLC26A4	O43511-1.1	A104K	Pathogenic	0.913
SLC26A4	O43511-1.1	A104L	Pathogenic	0.943
SLC26A4	O43511-1.1	A104M	Pathogenic	0.952
SLC26A4	O43511-1.1	A104N	Pathogenic	0.993
SLC26A4	O43511-1.1	A104P	Pathogenic	0.991
SLC26A4	O43511-1.1	A104Q	Pathogenic	0.973
SLC26A4	O43511-1.1	A104R	Pathogenic	0.853
SLC26A4	O43511-1.1	A104S	Pathogenic	0.984
SLC26A4	O43511-1.1	A104T	Pathogenic	0.983
SLC26A4	O43511-1.1	A104V	Pathogenic	0.959
SLC26A4	O43511-1.1	A104W	Pathogenic	0.903
SLC26A4	O43511-1.1	A104Y	Pathogenic	0.954
SLC26A4	O43511-1.1	Y105A	Pathogenic	0.859
SLC26A4	O43511-1.1	Y105C	Pathogenic	0.948
SLC26A4	O43511-1.1	Y105D	Pathogenic	0.96
SLC26A4	O43511-1.1	Y105E	Pathogenic	0.966
SLC26A4	O43511-1.1	Y105F	Pathogenic	0.789
SLC26A4	O43511-1.1	Y105G	Pathogenic	0.822
SLC26A4	O43511-1.1	Y105H	Pathogenic	0.777
SLC26A4	O43511-1.1	Y105I	Pathogenic	0.974
SLC26A4	O43511-1.1	Y105K	Pathogenic	0.988
SLC26A4	O43511-1.1	Y105L	Pathogenic	0.975
SLC26A4	O43511-1.1	Y105M	Pathogenic	0.979
SLC26A4	O43511-1.1	Y105N	Pathogenic	0.941
SLC26A4	O43511-1.1	Y105P	Pathogenic	0.976
SLC26A4	O43511-1.1	Y105Q	Pathogenic	0.954
SLC26A4	O43511-1.1	Y105R	Pathogenic	0.987
SLC26A4	O43511-1.1	Y105S	Pathogenic	0.875
SLC26A4	O43511-1.1	Y105T	Pathogenic	0.951
SLC26A4	O43511-1.1	Y105V	Pathogenic	0.952
SLC26A4	O43511-1.1	Y105W	Pathogenic	0.754
SLC26A4	O43511-1.1	A106C	Pathogenic	0.96
SLC26A4	O43511-1.1	A106D	Pathogenic	0.985
SLC26A4	O43511-1.1	A106E	Pathogenic	0.939
SLC26A4	O43511-1.1	A106F	Pathogenic	0.886
SLC26A4	O43511-1.1	A106G	Pathogenic	0.965
SLC26A4	O43511-1.1	A106H	Pathogenic	0.965
SLC26A4	O43511-1.1	A106I	Pathogenic	0.864
SLC26A4	O43511-1.1	A106K	Pathogenic	0.806
SLC26A4	O43511-1.1	A106L	Pathogenic	0.868
SLC26A4	O43511-1.1	A106M	Pathogenic	0.888
SLC26A4	O43511-1.1	A106N	Pathogenic	0.983
SLC26A4	O43511-1.1	A106P	Pathogenic	0.978
SLC26A4	O43511-1.1	A106Q	Pathogenic	0.935
SLC26A4	O43511-1.1	A106R	Pathogenic	0.697
SLC26A4	O43511-1.1	A106S	Pathogenic	0.961
SLC26A4	O43511-1.1	A106T	Pathogenic	0.957
SLC26A4	O43511-1.1	A106V	Pathogenic	0.903
SLC26A4	O43511-1.1	A106W	Pathogenic	0.787
SLC26A4	O43511-1.1	A106Y	Pathogenic	0.891
SLC26A4	O43511-1.1	L107A	Pathogenic	0.894
SLC26A4	O43511-1.1	L107C	Pathogenic	0.963
SLC26A4	O43511-1.1	L107D	Pathogenic	0.993
SLC26A4	O43511-1.1	L107E	Pathogenic	0.994
SLC26A4	O43511-1.1	L107F	Pathogenic	0.982
SLC26A4	O43511-1.1	L107G	Pathogenic	0.963
SLC26A4	O43511-1.1	L107H	Pathogenic	0.997
SLC26A4	O43511-1.1	L107I	Pathogenic	0.957
SLC26A4	O43511-1.1	L107K	Pathogenic	0.988
SLC26A4	O43511-1.1	L107M	Pathogenic	0.951
SLC26A4	O43511-1.1	L107N	Pathogenic	0.989
SLC26A4	O43511-1.1	L107P	Pathogenic	0.991
SLC26A4	O43511-1.1	L107Q	Pathogenic	0.991
SLC26A4	O43511-1.1	L107R	Pathogenic	0.978
SLC26A4	O43511-1.1	L107S	Pathogenic	0.951
SLC26A4	O43511-1.1	L107T	Pathogenic	0.964
SLC26A4	O43511-1.1	L107V	Pathogenic	0.943
SLC26A4	O43511-1.1	L107W	Pathogenic	0.981
SLC26A4	O43511-1.1	L107Y	Pathogenic	0.985
SLC26A4	O43511-1.1	L108A	Pathogenic	0.894
SLC26A4	O43511-1.1	L108C	Pathogenic	0.963
SLC26A4	O43511-1.1	L108D	Pathogenic	0.993
SLC26A4	O43511-1.1	L108E	Pathogenic	0.994
SLC26A4	O43511-1.1	L108F	Pathogenic	0.982
SLC26A4	O43511-1.1	L108G	Pathogenic	0.963
SLC26A4	O43511-1.1	L108H	Pathogenic	0.997
SLC26A4	O43511-1.1	L108I	Pathogenic	0.957
SLC26A4	O43511-1.1	L108K	Pathogenic	0.988
SLC26A4	O43511-1.1	L108M	Pathogenic	0.951
SLC26A4	O43511-1.1	L108N	Pathogenic	0.989
SLC26A4	O43511-1.1	L108P	Pathogenic	0.991
SLC26A4	O43511-1.1	L108Q	Pathogenic	0.991
SLC26A4	O43511-1.1	L108R	Pathogenic	0.978
SLC26A4	O43511-1.1	L108S	Pathogenic	0.951
SLC26A4	O43511-1.1	L108T	Pathogenic	0.964
SLC26A4	O43511-1.1	L108V	Pathogenic	0.943
SLC26A4	O43511-1.1	L108W	Pathogenic	0.981
SLC26A4	O43511-1.1	L108Y	Pathogenic	0.985
SLC26A4	O43511-1.1	A109C	Pathogenic	0.707
SLC26A4	O43511-1.1	A109D	Pathogenic	0.869
SLC26A4	O43511-1.1	A109E	Pathogenic	0.607
SLC26A4	O43511-1.1	A109F	Neutral	0.439
SLC26A4	O43511-1.1	A109G	Pathogenic	0.736
SLC26A4	O43511-1.1	A109H	Pathogenic	0.736
SLC26A4	O43511-1.1	A109I	Neutral	0.389
SLC26A4	O43511-1.1	A109K	Neutral	0.295
SLC26A4	O43511-1.1	A109L	Neutral	0.398
SLC26A4	O43511-1.1	A109M	Neutral	0.442
SLC26A4	O43511-1.1	A109N	Pathogenic	0.85
SLC26A4	O43511-1.1	A109P	Pathogenic	0.818
SLC26A4	O43511-1.1	A109Q	Pathogenic	0.592
SLC26A4	O43511-1.1	A109R	Neutral	0.188
SLC26A4	O43511-1.1	A109S	Pathogenic	0.711
SLC26A4	O43511-1.1	A109T	Pathogenic	0.691
SLC26A4	O43511-1.1	A109V	Neutral	0.483
SLC26A4	O43511-1.1	A109W	Neutral	0.271
SLC26A4	O43511-1.1	A109Y	Neutral	0.451
SLC26A4	O43511-1.1	A110C	Neutral	0.281
SLC26A4	O43511-1.1	A110D	Pathogenic	0.518
SLC26A4	O43511-1.1	A110E	Neutral	0.2
SLC26A4	O43511-1.1	A110F	Neutral	0.112
SLC26A4	O43511-1.1	A110G	Neutral	0.31
SLC26A4	O43511-1.1	A110H	Neutral	0.311
SLC26A4	O43511-1.1	A110I	Neutral	0.093
SLC26A4	O43511-1.1	A110K	Neutral	0.063
SLC26A4	O43511-1.1	A110L	Neutral	0.097
SLC26A4	O43511-1.1	A110M	Neutral	0.114
SLC26A4	O43511-1.1	A110N	Neutral	0.478
SLC26A4	O43511-1.1	A110P	Neutral	0.42
SLC26A4	O43511-1.1	A110Q	Neutral	0.19
SLC26A4	O43511-1.1	A110R	Neutral	0.036
SLC26A4	O43511-1.1	A110S	Neutral	0.284
SLC26A4	O43511-1.1	A110T	Neutral	0.266
SLC26A4	O43511-1.1	A110V	Neutral	0.131
SLC26A4	O43511-1.1	A110W	Neutral	0.057
SLC26A4	O43511-1.1	A110Y	Neutral	0.117
SLC26A4	O43511-1.1	V111A	Neutral	0.492
SLC26A4	O43511-1.1	V111C	Pathogenic	0.856
SLC26A4	O43511-1.1	V111D	Pathogenic	0.939
SLC26A4	O43511-1.1	V111E	Pathogenic	0.926
SLC26A4	O43511-1.1	V111F	Pathogenic	0.761
SLC26A4	O43511-1.1	V111G	Pathogenic	0.747
SLC26A4	O43511-1.1	V111H	Pathogenic	0.958
SLC26A4	O43511-1.1	V111I	Neutral	0.242
SLC26A4	O43511-1.1	V111K	Pathogenic	0.773
SLC26A4	O43511-1.1	V111L	Pathogenic	0.572
SLC26A4	O43511-1.1	V111M	Pathogenic	0.616
SLC26A4	O43511-1.1	V111N	Pathogenic	0.953
SLC26A4	O43511-1.1	V111P	Pathogenic	0.928
SLC26A4	O43511-1.1	V111Q	Pathogenic	0.922
SLC26A4	O43511-1.1	V111R	Pathogenic	0.791
SLC26A4	O43511-1.1	V111S	Pathogenic	0.818
SLC26A4	O43511-1.1	V111T	Pathogenic	0.754
SLC26A4	O43511-1.1	V111W	Pathogenic	0.752
SLC26A4	O43511-1.1	V111Y	Pathogenic	0.732
SLC26A4	O43511-1.1	P112A	Pathogenic	0.995
SLC26A4	O43511-1.1	P112C	Pathogenic	1.0
SLC26A4	O43511-1.1	P112D	Pathogenic	0.997
SLC26A4	O43511-1.1	P112E	Pathogenic	0.994
SLC26A4	O43511-1.1	P112F	Pathogenic	0.998
SLC26A4	O43511-1.1	P112G	Pathogenic	0.994
SLC26A4	O43511-1.1	P112H	Pathogenic	0.997
SLC26A4	O43511-1.1	P112I	Pathogenic	0.997
SLC26A4	O43511-1.1	P112K	Pathogenic	0.979
SLC26A4	O43511-1.1	P112L	Pathogenic	0.998
SLC26A4	O43511-1.1	P112M	Pathogenic	0.996
SLC26A4	O43511-1.1	P112N	Pathogenic	0.998
SLC26A4	O43511-1.1	P112Q	Pathogenic	0.994
SLC26A4	O43511-1.1	P112R	Pathogenic	0.981
SLC26A4	O43511-1.1	P112S	Pathogenic	0.996
SLC26A4	O43511-1.1	P112T	Pathogenic	0.998
SLC26A4	O43511-1.1	P112V	Pathogenic	0.998
SLC26A4	O43511-1.1	P112W	Pathogenic	0.991
SLC26A4	O43511-1.1	P112Y	Pathogenic	0.996
SLC26A4	O43511-1.1	V113A	Neutral	0.124
SLC26A4	O43511-1.1	V113C	Neutral	0.466
SLC26A4	O43511-1.1	V113D	Pathogenic	0.692
SLC26A4	O43511-1.1	V113E	Pathogenic	0.649
SLC26A4	O43511-1.1	V113F	Neutral	0.318
SLC26A4	O43511-1.1	V113G	Neutral	0.303
SLC26A4	O43511-1.1	V113H	Pathogenic	0.769
SLC26A4	O43511-1.1	V113I	Neutral	0.045
SLC26A4	O43511-1.1	V113K	Neutral	0.333
SLC26A4	O43511-1.1	V113L	Neutral	0.164
SLC26A4	O43511-1.1	V113M	Neutral	0.191
SLC26A4	O43511-1.1	V113N	Pathogenic	0.75
SLC26A4	O43511-1.1	V113P	Pathogenic	0.655
SLC26A4	O43511-1.1	V113Q	Pathogenic	0.634
SLC26A4	O43511-1.1	V113R	Neutral	0.357
SLC26A4	O43511-1.1	V113S	Neutral	0.397
SLC26A4	O43511-1.1	V113T	Neutral	0.311
SLC26A4	O43511-1.1	V113W	Neutral	0.308
SLC26A4	O43511-1.1	V113Y	Neutral	0.287
SLC26A4	O43511-1.1	G114A	Neutral	0.325
SLC26A4	O43511-1.1	G114C	Pathogenic	0.561
SLC26A4	O43511-1.1	G114D	Neutral	0.215
SLC26A4	O43511-1.1	G114E	Neutral	0.204
SLC26A4	O43511-1.1	G114F	Neutral	0.093
SLC26A4	O43511-1.1	G114H	Neutral	0.172
SLC26A4	O43511-1.1	G114I	Neutral	0.252
SLC26A4	O43511-1.1	G114K	Neutral	0.065
SLC26A4	O43511-1.1	G114L	Neutral	0.259
SLC26A4	O43511-1.1	G114M	Neutral	0.173
SLC26A4	O43511-1.1	G114N	Neutral	0.104
SLC26A4	O43511-1.1	G114P	Neutral	0.37
SLC26A4	O43511-1.1	G114Q	Neutral	0.194
SLC26A4	O43511-1.1	G114R	Neutral	0.037
SLC26A4	O43511-1.1	G114S	Neutral	0.29
SLC26A4	O43511-1.1	G114T	Neutral	0.38
SLC26A4	O43511-1.1	G114V	Neutral	0.331
SLC26A4	O43511-1.1	G114W	Neutral	0.012
SLC26A4	O43511-1.1	G114Y	Neutral	0.097
SLC26A4	O43511-1.1	Y115A	Pathogenic	0.976
SLC26A4	O43511-1.1	Y115C	Pathogenic	0.992
SLC26A4	O43511-1.1	Y115D	Pathogenic	0.994
SLC26A4	O43511-1.1	Y115E	Pathogenic	0.995
SLC26A4	O43511-1.1	Y115F	Pathogenic	0.962
SLC26A4	O43511-1.1	Y115G	Pathogenic	0.969
SLC26A4	O43511-1.1	Y115H	Pathogenic	0.959
SLC26A4	O43511-1.1	Y115I	Pathogenic	0.996
SLC26A4	O43511-1.1	Y115K	Pathogenic	0.998
SLC26A4	O43511-1.1	Y115L	Pathogenic	0.996
SLC26A4	O43511-1.1	Y115M	Pathogenic	0.997
SLC26A4	O43511-1.1	Y115N	Pathogenic	0.991
SLC26A4	O43511-1.1	Y115P	Pathogenic	0.996
SLC26A4	O43511-1.1	Y115Q	Pathogenic	0.993
SLC26A4	O43511-1.1	Y115R	Pathogenic	0.998
SLC26A4	O43511-1.1	Y115S	Pathogenic	0.979
SLC26A4	O43511-1.1	Y115T	Pathogenic	0.992
SLC26A4	O43511-1.1	Y115V	Pathogenic	0.993
SLC26A4	O43511-1.1	Y115W	Pathogenic	0.954
SLC26A4	O43511-1.1	G116A	Pathogenic	0.989
SLC26A4	O43511-1.1	G116C	Pathogenic	0.996
SLC26A4	O43511-1.1	G116D	Pathogenic	0.982
SLC26A4	O43511-1.1	G116E	Pathogenic	0.98
SLC26A4	O43511-1.1	G116F	Pathogenic	0.952
SLC26A4	O43511-1.1	G116H	Pathogenic	0.976
SLC26A4	O43511-1.1	G116I	Pathogenic	0.985
SLC26A4	O43511-1.1	G116K	Pathogenic	0.931
SLC26A4	O43511-1.1	G116L	Pathogenic	0.985
SLC26A4	O43511-1.1	G116M	Pathogenic	0.976
SLC26A4	O43511-1.1	G116N	Pathogenic	0.957
SLC26A4	O43511-1.1	G116P	Pathogenic	0.991
SLC26A4	O43511-1.1	G116Q	Pathogenic	0.979
SLC26A4	O43511-1.1	G116R	Pathogenic	0.881
SLC26A4	O43511-1.1	G116S	Pathogenic	0.987
SLC26A4	O43511-1.1	G116T	Pathogenic	0.992
SLC26A4	O43511-1.1	G116V	Pathogenic	0.99
SLC26A4	O43511-1.1	G116W	Pathogenic	0.7
SLC26A4	O43511-1.1	G116Y	Pathogenic	0.954
SLC26A4	O43511-1.1	L117A	Pathogenic	0.894
SLC26A4	O43511-1.1	L117C	Pathogenic	0.963
SLC26A4	O43511-1.1	L117D	Pathogenic	0.993
SLC26A4	O43511-1.1	L117E	Pathogenic	0.994
SLC26A4	O43511-1.1	L117F	Pathogenic	0.982
SLC26A4	O43511-1.1	L117G	Pathogenic	0.963
SLC26A4	O43511-1.1	L117H	Pathogenic	0.997
SLC26A4	O43511-1.1	L117I	Pathogenic	0.957
SLC26A4	O43511-1.1	L117K	Pathogenic	0.988
SLC26A4	O43511-1.1	L117M	Pathogenic	0.951
SLC26A4	O43511-1.1	L117N	Pathogenic	0.989
SLC26A4	O43511-1.1	L117P	Pathogenic	0.991
SLC26A4	O43511-1.1	L117Q	Pathogenic	0.991
SLC26A4	O43511-1.1	L117R	Pathogenic	0.978
SLC26A4	O43511-1.1	L117S	Pathogenic	0.951
SLC26A4	O43511-1.1	L117T	Pathogenic	0.964
SLC26A4	O43511-1.1	L117V	Pathogenic	0.943
SLC26A4	O43511-1.1	L117W	Pathogenic	0.981
SLC26A4	O43511-1.1	L117Y	Pathogenic	0.985
SLC26A4	O43511-1.1	Y118A	Pathogenic	0.983
SLC26A4	O43511-1.1	Y118C	Pathogenic	0.994
SLC26A4	O43511-1.1	Y118D	Pathogenic	0.996
SLC26A4	O43511-1.1	Y118E	Pathogenic	0.996
SLC26A4	O43511-1.1	Y118F	Pathogenic	0.972
SLC26A4	O43511-1.1	Y118G	Pathogenic	0.978
SLC26A4	O43511-1.1	Y118H	Pathogenic	0.971
SLC26A4	O43511-1.1	Y118I	Pathogenic	0.997
SLC26A4	O43511-1.1	Y118K	Pathogenic	0.999
SLC26A4	O43511-1.1	Y118L	Pathogenic	0.997
SLC26A4	O43511-1.1	Y118M	Pathogenic	0.998
SLC26A4	O43511-1.1	Y118N	Pathogenic	0.993
SLC26A4	O43511-1.1	Y118P	Pathogenic	0.997
SLC26A4	O43511-1.1	Y118Q	Pathogenic	0.995
SLC26A4	O43511-1.1	Y118R	Pathogenic	0.999
SLC26A4	O43511-1.1	Y118S	Pathogenic	0.985
SLC26A4	O43511-1.1	Y118T	Pathogenic	0.995
SLC26A4	O43511-1.1	Y118V	Pathogenic	0.995
SLC26A4	O43511-1.1	Y118W	Pathogenic	0.966
SLC26A4	O43511-1.1	S119A	Pathogenic	0.731
SLC26A4	O43511-1.1	S119C	Pathogenic	0.86
SLC26A4	O43511-1.1	S119D	Pathogenic	0.732
SLC26A4	O43511-1.1	S119E	Pathogenic	0.561
SLC26A4	O43511-1.1	S119F	Neutral	0.498
SLC26A4	O43511-1.1	S119G	Pathogenic	0.723
SLC26A4	O43511-1.1	S119H	Pathogenic	0.669
SLC26A4	O43511-1.1	S119I	Pathogenic	0.619
SLC26A4	O43511-1.1	S119K	Neutral	0.256
SLC26A4	O43511-1.1	S119L	Pathogenic	0.628
SLC26A4	O43511-1.1	S119M	Pathogenic	0.502
SLC26A4	O43511-1.1	S119N	Pathogenic	0.537
SLC26A4	O43511-1.1	S119P	Pathogenic	0.851
SLC26A4	O43511-1.1	S119Q	Pathogenic	0.545
SLC26A4	O43511-1.1	S119R	Neutral	0.277
SLC26A4	O43511-1.1	S119T	Pathogenic	0.596
SLC26A4	O43511-1.1	S119V	Pathogenic	0.827
SLC26A4	O43511-1.1	S119W	Neutral	0.321
SLC26A4	O43511-1.1	S119Y	Pathogenic	0.51
SLC26A4	O43511-1.1	A120C	Pathogenic	0.942
SLC26A4	O43511-1.1	A120D	Pathogenic	0.978
SLC26A4	O43511-1.1	A120E	Pathogenic	0.912
SLC26A4	O43511-1.1	A120F	Pathogenic	0.84
SLC26A4	O43511-1.1	A120G	Pathogenic	0.949
SLC26A4	O43511-1.1	A120H	Pathogenic	0.949
SLC26A4	O43511-1.1	A120I	Pathogenic	0.811
SLC26A4	O43511-1.1	A120K	Pathogenic	0.738
SLC26A4	O43511-1.1	A120L	Pathogenic	0.817
SLC26A4	O43511-1.1	A120M	Pathogenic	0.842
SLC26A4	O43511-1.1	A120N	Pathogenic	0.974
SLC26A4	O43511-1.1	A120P	Pathogenic	0.968
SLC26A4	O43511-1.1	A120Q	Pathogenic	0.907
SLC26A4	O43511-1.1	A120R	Pathogenic	0.609
SLC26A4	O43511-1.1	A120S	Pathogenic	0.943
SLC26A4	O43511-1.1	A120T	Pathogenic	0.938
SLC26A4	O43511-1.1	A120V	Pathogenic	0.863
SLC26A4	O43511-1.1	A120W	Pathogenic	0.714
SLC26A4	O43511-1.1	A120Y	Pathogenic	0.847
SLC26A4	O43511-1.1	F121A	Pathogenic	0.967
SLC26A4	O43511-1.1	F121C	Pathogenic	0.989
SLC26A4	O43511-1.1	F121D	Pathogenic	0.991
SLC26A4	O43511-1.1	F121E	Pathogenic	0.996
SLC26A4	O43511-1.1	F121G	Pathogenic	0.957
SLC26A4	O43511-1.1	F121H	Pathogenic	0.993
SLC26A4	O43511-1.1	F121I	Pathogenic	0.994
SLC26A4	O43511-1.1	F121K	Pathogenic	0.999
SLC26A4	O43511-1.1	F121L	Pathogenic	0.994
SLC26A4	O43511-1.1	F121M	Pathogenic	0.993
SLC26A4	O43511-1.1	F121N	Pathogenic	0.994
SLC26A4	O43511-1.1	F121P	Pathogenic	0.997
SLC26A4	O43511-1.1	F121Q	Pathogenic	0.998
SLC26A4	O43511-1.1	F121R	Pathogenic	0.998
SLC26A4	O43511-1.1	F121S	Pathogenic	0.971
SLC26A4	O43511-1.1	F121T	Pathogenic	0.989
SLC26A4	O43511-1.1	F121V	Pathogenic	0.991
SLC26A4	O43511-1.1	F121W	Pathogenic	0.97
SLC26A4	O43511-1.1	F121Y	Pathogenic	0.95
SLC26A4	O43511-1.1	F122A	Pathogenic	0.918
SLC26A4	O43511-1.1	F122C	Pathogenic	0.972
SLC26A4	O43511-1.1	F122D	Pathogenic	0.978
SLC26A4	O43511-1.1	F122E	Pathogenic	0.991
SLC26A4	O43511-1.1	F122G	Pathogenic	0.895
SLC26A4	O43511-1.1	F122H	Pathogenic	0.981
SLC26A4	O43511-1.1	F122I	Pathogenic	0.985
SLC26A4	O43511-1.1	F122K	Pathogenic	0.997
SLC26A4	O43511-1.1	F122L	Pathogenic	0.984
SLC26A4	O43511-1.1	F122M	Pathogenic	0.981
SLC26A4	O43511-1.1	F122N	Pathogenic	0.983
SLC26A4	O43511-1.1	F122P	Pathogenic	0.993
SLC26A4	O43511-1.1	F122Q	Pathogenic	0.994
SLC26A4	O43511-1.1	F122R	Pathogenic	0.994
SLC26A4	O43511-1.1	F122S	Pathogenic	0.928
SLC26A4	O43511-1.1	F122T	Pathogenic	0.973
SLC26A4	O43511-1.1	F122V	Pathogenic	0.978
SLC26A4	O43511-1.1	F122W	Pathogenic	0.926
SLC26A4	O43511-1.1	F122Y	Pathogenic	0.879
SLC26A4	O43511-1.1	P123A	Pathogenic	0.996
SLC26A4	O43511-1.1	P123C	Pathogenic	1.0
SLC26A4	O43511-1.1	P123D	Pathogenic	0.998
SLC26A4	O43511-1.1	P123E	Pathogenic	0.996
SLC26A4	O43511-1.1	P123F	Pathogenic	0.998
SLC26A4	O43511-1.1	P123G	Pathogenic	0.995
SLC26A4	O43511-1.1	P123H	Pathogenic	0.998
SLC26A4	O43511-1.1	P123I	Pathogenic	0.998
SLC26A4	O43511-1.1	P123K	Pathogenic	0.984
SLC26A4	O43511-1.1	P123L	Pathogenic	0.998
SLC26A4	O43511-1.1	P123M	Pathogenic	0.997
SLC26A4	O43511-1.1	P123N	Pathogenic	0.999
SLC26A4	O43511-1.1	P123Q	Pathogenic	0.995
SLC26A4	O43511-1.1	P123R	Pathogenic	0.985
SLC26A4	O43511-1.1	P123S	Pathogenic	0.997
SLC26A4	O43511-1.1	P123T	Pathogenic	0.998
SLC26A4	O43511-1.1	P123V	Pathogenic	0.999
SLC26A4	O43511-1.1	P123W	Pathogenic	0.993
SLC26A4	O43511-1.1	P123Y	Pathogenic	0.997
SLC26A4	O43511-1.1	I124A	Neutral	0.142
SLC26A4	O43511-1.1	I124C	Neutral	0.336
SLC26A4	O43511-1.1	I124D	Pathogenic	0.566
SLC26A4	O43511-1.1	I124E	Pathogenic	0.756
SLC26A4	O43511-1.1	I124F	Pathogenic	0.538
SLC26A4	O43511-1.1	I124G	Neutral	0.336
SLC26A4	O43511-1.1	I124H	Pathogenic	0.862
SLC26A4	O43511-1.1	I124K	Pathogenic	0.764
SLC26A4	O43511-1.1	I124L	Neutral	0.314
SLC26A4	O43511-1.1	I124M	Neutral	0.434
SLC26A4	O43511-1.1	I124N	Pathogenic	0.636
SLC26A4	O43511-1.1	I124P	Pathogenic	0.689
SLC26A4	O43511-1.1	I124Q	Pathogenic	0.82
SLC26A4	O43511-1.1	I124R	Pathogenic	0.641
SLC26A4	O43511-1.1	I124S	Neutral	0.276
SLC26A4	O43511-1.1	I124T	Neutral	0.344
SLC26A4	O43511-1.1	I124V	Neutral	0.074
SLC26A4	O43511-1.1	I124W	Pathogenic	0.693
SLC26A4	O43511-1.1	I124Y	Pathogenic	0.564
SLC26A4	O43511-1.1	L125A	Neutral	0.248
SLC26A4	O43511-1.1	L125C	Pathogenic	0.503
SLC26A4	O43511-1.1	L125D	Pathogenic	0.839
SLC26A4	O43511-1.1	L125E	Pathogenic	0.861
SLC26A4	O43511-1.1	L125F	Pathogenic	0.685
SLC26A4	O43511-1.1	L125G	Pathogenic	0.502
SLC26A4	O43511-1.1	L125H	Pathogenic	0.926
SLC26A4	O43511-1.1	L125I	Neutral	0.468
SLC26A4	O43511-1.1	L125K	Pathogenic	0.763
SLC26A4	O43511-1.1	L125M	Neutral	0.433
SLC26A4	O43511-1.1	L125N	Pathogenic	0.777
SLC26A4	O43511-1.1	L125P	Pathogenic	0.815
SLC26A4	O43511-1.1	L125Q	Pathogenic	0.819
SLC26A4	O43511-1.1	L125R	Pathogenic	0.64
SLC26A4	O43511-1.1	L125S	Neutral	0.433
SLC26A4	O43511-1.1	L125T	Pathogenic	0.512
SLC26A4	O43511-1.1	L125V	Neutral	0.393
SLC26A4	O43511-1.1	L125W	Pathogenic	0.674
SLC26A4	O43511-1.1	L125Y	Pathogenic	0.721
SLC26A4	O43511-1.1	T126A	Neutral	0.486
SLC26A4	O43511-1.1	T126C	Pathogenic	0.775
SLC26A4	O43511-1.1	T126D	Pathogenic	0.794
SLC26A4	O43511-1.1	T126E	Pathogenic	0.683
SLC26A4	O43511-1.1	T126F	Pathogenic	0.511
SLC26A4	O43511-1.1	T126G	Pathogenic	0.599
SLC26A4	O43511-1.1	T126H	Pathogenic	0.795
SLC26A4	O43511-1.1	T126I	Neutral	0.46
SLC26A4	O43511-1.1	T126K	Neutral	0.368
SLC26A4	O43511-1.1	T126L	Neutral	0.47
SLC26A4	O43511-1.1	T126M	Pathogenic	0.515
SLC26A4	O43511-1.1	T126N	Pathogenic	0.662
SLC26A4	O43511-1.1	T126P	Pathogenic	0.821
SLC26A4	O43511-1.1	T126Q	Pathogenic	0.669
SLC26A4	O43511-1.1	T126R	Neutral	0.243
SLC26A4	O43511-1.1	T126S	Neutral	0.36
SLC26A4	O43511-1.1	T126V	Pathogenic	0.556
SLC26A4	O43511-1.1	T126W	Neutral	0.198
SLC26A4	O43511-1.1	T126Y	Pathogenic	0.524
SLC26A4	O43511-1.1	Y127A	Pathogenic	0.992
SLC26A4	O43511-1.1	Y127C	Pathogenic	0.997
SLC26A4	O43511-1.1	Y127D	Pathogenic	0.998
SLC26A4	O43511-1.1	Y127E	Pathogenic	0.998
SLC26A4	O43511-1.1	Y127F	Pathogenic	0.987
SLC26A4	O43511-1.1	Y127G	Pathogenic	0.99
SLC26A4	O43511-1.1	Y127H	Pathogenic	0.986
SLC26A4	O43511-1.1	Y127I	Pathogenic	0.999
SLC26A4	O43511-1.1	Y127K	Pathogenic	0.999
SLC26A4	O43511-1.1	Y127L	Pathogenic	0.999
SLC26A4	O43511-1.1	Y127M	Pathogenic	0.999
SLC26A4	O43511-1.1	Y127N	Pathogenic	0.997
SLC26A4	O43511-1.1	Y127P	Pathogenic	0.999
SLC26A4	O43511-1.1	Y127Q	Pathogenic	0.998
SLC26A4	O43511-1.1	Y127R	Pathogenic	0.999
SLC26A4	O43511-1.1	Y127S	Pathogenic	0.993
SLC26A4	O43511-1.1	Y127T	Pathogenic	0.997
SLC26A4	O43511-1.1	Y127V	Pathogenic	0.998
SLC26A4	O43511-1.1	Y127W	Pathogenic	0.984
SLC26A4	O43511-1.1	F128A	Pathogenic	0.885
SLC26A4	O43511-1.1	F128C	Pathogenic	0.959
SLC26A4	O43511-1.1	F128D	Pathogenic	0.968
SLC26A4	O43511-1.1	F128E	Pathogenic	0.986
SLC26A4	O43511-1.1	F128G	Pathogenic	0.854
SLC26A4	O43511-1.1	F128H	Pathogenic	0.973
SLC26A4	O43511-1.1	F128I	Pathogenic	0.978
SLC26A4	O43511-1.1	F128K	Pathogenic	0.995
SLC26A4	O43511-1.1	F128L	Pathogenic	0.977
SLC26A4	O43511-1.1	F128M	Pathogenic	0.973
SLC26A4	O43511-1.1	F128N	Pathogenic	0.976
SLC26A4	O43511-1.1	F128P	Pathogenic	0.99
SLC26A4	O43511-1.1	F128Q	Pathogenic	0.991
SLC26A4	O43511-1.1	F128R	Pathogenic	0.991
SLC26A4	O43511-1.1	F128S	Pathogenic	0.898
SLC26A4	O43511-1.1	F128T	Pathogenic	0.961
SLC26A4	O43511-1.1	F128V	Pathogenic	0.968
SLC26A4	O43511-1.1	F128W	Pathogenic	0.895
SLC26A4	O43511-1.1	F128Y	Pathogenic	0.832
SLC26A4	O43511-1.1	I129A	Neutral	0.145
SLC26A4	O43511-1.1	I129C	Neutral	0.342
SLC26A4	O43511-1.1	I129D	Pathogenic	0.572
SLC26A4	O43511-1.1	I129E	Pathogenic	0.76
SLC26A4	O43511-1.1	I129F	Pathogenic	0.544
SLC26A4	O43511-1.1	I129G	Neutral	0.341
SLC26A4	O43511-1.1	I129H	Pathogenic	0.865
SLC26A4	O43511-1.1	I129K	Pathogenic	0.768
SLC26A4	O43511-1.1	I129L	Neutral	0.319
SLC26A4	O43511-1.1	I129M	Neutral	0.44
SLC26A4	O43511-1.1	I129N	Pathogenic	0.641
SLC26A4	O43511-1.1	I129P	Pathogenic	0.694
SLC26A4	O43511-1.1	I129Q	Pathogenic	0.823
SLC26A4	O43511-1.1	I129R	Pathogenic	0.647
SLC26A4	O43511-1.1	I129S	Neutral	0.281
SLC26A4	O43511-1.1	I129T	Neutral	0.35
SLC26A4	O43511-1.1	I129V	Neutral	0.076
SLC26A4	O43511-1.1	I129W	Pathogenic	0.698
SLC26A4	O43511-1.1	I129Y	Pathogenic	0.57
SLC26A4	O43511-1.1	F130A	Pathogenic	0.668
SLC26A4	O43511-1.1	F130C	Pathogenic	0.86
SLC26A4	O43511-1.1	F130D	Pathogenic	0.887
SLC26A4	O43511-1.1	F130E	Pathogenic	0.949
SLC26A4	O43511-1.1	F130G	Pathogenic	0.604
SLC26A4	O43511-1.1	F130H	Pathogenic	0.903
SLC26A4	O43511-1.1	F130I	Pathogenic	0.92
SLC26A4	O43511-1.1	F130K	Pathogenic	0.981
SLC26A4	O43511-1.1	F130L	Pathogenic	0.918
SLC26A4	O43511-1.1	F130M	Pathogenic	0.903
SLC26A4	O43511-1.1	F130N	Pathogenic	0.913
SLC26A4	O43511-1.1	F130P	Pathogenic	0.964
SLC26A4	O43511-1.1	F130Q	Pathogenic	0.965
SLC26A4	O43511-1.1	F130R	Pathogenic	0.967
SLC26A4	O43511-1.1	F130S	Pathogenic	0.698
SLC26A4	O43511-1.1	F130T	Pathogenic	0.864
SLC26A4	O43511-1.1	F130V	Pathogenic	0.888
SLC26A4	O43511-1.1	F130W	Pathogenic	0.691
SLC26A4	O43511-1.1	F130Y	Pathogenic	0.565
SLC26A4	O43511-1.1	G131A	Pathogenic	0.992
SLC26A4	O43511-1.1	G131C	Pathogenic	0.997
SLC26A4	O43511-1.1	G131D	Pathogenic	0.987
SLC26A4	O43511-1.1	G131E	Pathogenic	0.986
SLC26A4	O43511-1.1	G131F	Pathogenic	0.965
SLC26A4	O43511-1.1	G131H	Pathogenic	0.982
SLC26A4	O43511-1.1	G131I	Pathogenic	0.989
SLC26A4	O43511-1.1	G131K	Pathogenic	0.949
SLC26A4	O43511-1.1	G131L	Pathogenic	0.99
SLC26A4	O43511-1.1	G131M	Pathogenic	0.983
SLC26A4	O43511-1.1	G131N	Pathogenic	0.969
SLC26A4	O43511-1.1	G131P	Pathogenic	0.994
SLC26A4	O43511-1.1	G131Q	Pathogenic	0.985
SLC26A4	O43511-1.1	G131R	Pathogenic	0.912
SLC26A4	O43511-1.1	G131S	Pathogenic	0.991
SLC26A4	O43511-1.1	G131T	Pathogenic	0.994
SLC26A4	O43511-1.1	G131V	Pathogenic	0.993
SLC26A4	O43511-1.1	G131W	Pathogenic	0.765
SLC26A4	O43511-1.1	G131Y	Pathogenic	0.967
SLC26A4	O43511-1.1	T132A	Pathogenic	0.994
SLC26A4	O43511-1.1	T132C	Pathogenic	0.998
SLC26A4	O43511-1.1	T132D	Pathogenic	0.999
SLC26A4	O43511-1.1	T132E	Pathogenic	0.997
SLC26A4	O43511-1.1	T132F	Pathogenic	0.995
SLC26A4	O43511-1.1	T132G	Pathogenic	0.996
SLC26A4	O43511-1.1	T132H	Pathogenic	0.999
SLC26A4	O43511-1.1	T132I	Pathogenic	0.993
SLC26A4	O43511-1.1	T132K	Pathogenic	0.99
SLC26A4	O43511-1.1	T132L	Pathogenic	0.994
SLC26A4	O43511-1.1	T132M	Pathogenic	0.995
SLC26A4	O43511-1.1	T132N	Pathogenic	0.997
SLC26A4	O43511-1.1	T132P	Pathogenic	0.999
SLC26A4	O43511-1.1	T132Q	Pathogenic	0.997
SLC26A4	O43511-1.1	T132R	Pathogenic	0.983
SLC26A4	O43511-1.1	T132S	Pathogenic	0.99
SLC26A4	O43511-1.1	T132V	Pathogenic	0.995
SLC26A4	O43511-1.1	T132W	Pathogenic	0.977
SLC26A4	O43511-1.1	T132Y	Pathogenic	0.995
SLC26A4	O43511-1.1	S133A	Pathogenic	0.989
SLC26A4	O43511-1.1	S133C	Pathogenic	0.995
SLC26A4	O43511-1.1	S133D	Pathogenic	0.989
SLC26A4	O43511-1.1	S133E	Pathogenic	0.977
SLC26A4	O43511-1.1	S133F	Pathogenic	0.971
SLC26A4	O43511-1.1	S133G	Pathogenic	0.989
SLC26A4	O43511-1.1	S133H	Pathogenic	0.985
SLC26A4	O43511-1.1	S133I	Pathogenic	0.982
SLC26A4	O43511-1.1	S133K	Pathogenic	0.92
SLC26A4	O43511-1.1	S133L	Pathogenic	0.983
SLC26A4	O43511-1.1	S133M	Pathogenic	0.971
SLC26A4	O43511-1.1	S133N	Pathogenic	0.975
SLC26A4	O43511-1.1	S133P	Pathogenic	0.995
SLC26A4	O43511-1.1	S133Q	Pathogenic	0.976
SLC26A4	O43511-1.1	S133R	Pathogenic	0.927
SLC26A4	O43511-1.1	S133T	Pathogenic	0.98
SLC26A4	O43511-1.1	S133V	Pathogenic	0.994
SLC26A4	O43511-1.1	S133W	Pathogenic	0.94
SLC26A4	O43511-1.1	S133Y	Pathogenic	0.972
SLC26A4	O43511-1.1	R134A	Pathogenic	0.831
SLC26A4	O43511-1.1	R134C	Pathogenic	0.973
SLC26A4	O43511-1.1	R134D	Pathogenic	0.978
SLC26A4	O43511-1.1	R134E	Pathogenic	0.959
SLC26A4	O43511-1.1	R134F	Pathogenic	0.996
SLC26A4	O43511-1.1	R134G	Pathogenic	0.825
SLC26A4	O43511-1.1	R134H	Pathogenic	0.963
SLC26A4	O43511-1.1	R134I	Pathogenic	0.993
SLC26A4	O43511-1.1	R134K	Pathogenic	0.956
SLC26A4	O43511-1.1	R134L	Pathogenic	0.987
SLC26A4	O43511-1.1	R134M	Pathogenic	0.978
SLC26A4	O43511-1.1	R134N	Pathogenic	0.928
SLC26A4	O43511-1.1	R134P	Pathogenic	0.96
SLC26A4	O43511-1.1	R134Q	Pathogenic	0.926
SLC26A4	O43511-1.1	R134S	Pathogenic	0.881
SLC26A4	O43511-1.1	R134T	Pathogenic	0.942
SLC26A4	O43511-1.1	R134V	Pathogenic	0.987
SLC26A4	O43511-1.1	R134W	Pathogenic	0.995
SLC26A4	O43511-1.1	R134Y	Pathogenic	0.995
SLC26A4	O43511-1.1	H135A	Pathogenic	1.0
SLC26A4	O43511-1.1	H135C	Pathogenic	1.0
SLC26A4	O43511-1.1	H135D	Pathogenic	1.0
SLC26A4	O43511-1.1	H135E	Pathogenic	1.0
SLC26A4	O43511-1.1	H135F	Pathogenic	1.0
SLC26A4	O43511-1.1	H135G	Pathogenic	0.999
SLC26A4	O43511-1.1	H135I	Pathogenic	1.0
SLC26A4	O43511-1.1	H135K	Pathogenic	1.0
SLC26A4	O43511-1.1	H135L	Pathogenic	1.0
SLC26A4	O43511-1.1	H135M	Pathogenic	1.0
SLC26A4	O43511-1.1	H135N	Pathogenic	0.999
SLC26A4	O43511-1.1	H135P	Pathogenic	1.0
SLC26A4	O43511-1.1	H135Q	Pathogenic	1.0
SLC26A4	O43511-1.1	H135R	Pathogenic	0.999
SLC26A4	O43511-1.1	H135S	Pathogenic	0.999
SLC26A4	O43511-1.1	H135T	Pathogenic	1.0
SLC26A4	O43511-1.1	H135V	Pathogenic	1.0
SLC26A4	O43511-1.1	H135W	Pathogenic	0.999
SLC26A4	O43511-1.1	H135Y	Pathogenic	0.997
SLC26A4	O43511-1.1	I136A	Pathogenic	0.859
SLC26A4	O43511-1.1	I136C	Pathogenic	0.949
SLC26A4	O43511-1.1	I136D	Pathogenic	0.98
SLC26A4	O43511-1.1	I136E	Pathogenic	0.991
SLC26A4	O43511-1.1	I136F	Pathogenic	0.977
SLC26A4	O43511-1.1	I136G	Pathogenic	0.949
SLC26A4	O43511-1.1	I136H	Pathogenic	0.996
SLC26A4	O43511-1.1	I136K	Pathogenic	0.992
SLC26A4	O43511-1.1	I136L	Pathogenic	0.944
SLC26A4	O43511-1.1	I136M	Pathogenic	0.966
SLC26A4	O43511-1.1	I136N	Pathogenic	0.985
SLC26A4	O43511-1.1	I136P	Pathogenic	0.988
SLC26A4	O43511-1.1	I136Q	Pathogenic	0.994
SLC26A4	O43511-1.1	I136R	Pathogenic	0.985
SLC26A4	O43511-1.1	I136S	Pathogenic	0.934
SLC26A4	O43511-1.1	I136T	Pathogenic	0.951
SLC26A4	O43511-1.1	I136V	Pathogenic	0.748
SLC26A4	O43511-1.1	I136W	Pathogenic	0.988
SLC26A4	O43511-1.1	I136Y	Pathogenic	0.98
SLC26A4	O43511-1.1	S137A	Pathogenic	0.979
SLC26A4	O43511-1.1	S137C	Pathogenic	0.99
SLC26A4	O43511-1.1	S137D	Pathogenic	0.979
SLC26A4	O43511-1.1	S137E	Pathogenic	0.955
SLC26A4	O43511-1.1	S137F	Pathogenic	0.943
SLC26A4	O43511-1.1	S137G	Pathogenic	0.978
SLC26A4	O43511-1.1	S137H	Pathogenic	0.971
SLC26A4	O43511-1.1	S137I	Pathogenic	0.965
SLC26A4	O43511-1.1	S137K	Pathogenic	0.853
SLC26A4	O43511-1.1	S137L	Pathogenic	0.966
SLC26A4	O43511-1.1	S137M	Pathogenic	0.944
SLC26A4	O43511-1.1	S137N	Pathogenic	0.951
SLC26A4	O43511-1.1	S137P	Pathogenic	0.99
SLC26A4	O43511-1.1	S137Q	Pathogenic	0.953
SLC26A4	O43511-1.1	S137R	Pathogenic	0.865
SLC26A4	O43511-1.1	S137T	Pathogenic	0.961
SLC26A4	O43511-1.1	S137V	Pathogenic	0.988
SLC26A4	O43511-1.1	S137W	Pathogenic	0.888
SLC26A4	O43511-1.1	S137Y	Pathogenic	0.946
SLC26A4	O43511-1.1	V138A	Pathogenic	0.746
SLC26A4	O43511-1.1	V138C	Pathogenic	0.948
SLC26A4	O43511-1.1	V138D	Pathogenic	0.979
SLC26A4	O43511-1.1	V138E	Pathogenic	0.975
SLC26A4	O43511-1.1	V138F	Pathogenic	0.906
SLC26A4	O43511-1.1	V138G	Pathogenic	0.9
SLC26A4	O43511-1.1	V138H	Pathogenic	0.986
SLC26A4	O43511-1.1	V138I	Neutral	0.492
SLC26A4	O43511-1.1	V138K	Pathogenic	0.912
SLC26A4	O43511-1.1	V138L	Pathogenic	0.803
SLC26A4	O43511-1.1	V138M	Pathogenic	0.83
SLC26A4	O43511-1.1	V138N	Pathogenic	0.984
SLC26A4	O43511-1.1	V138P	Pathogenic	0.975
SLC26A4	O43511-1.1	V138Q	Pathogenic	0.973
SLC26A4	O43511-1.1	V138R	Pathogenic	0.92
SLC26A4	O43511-1.1	V138S	Pathogenic	0.932
SLC26A4	O43511-1.1	V138T	Pathogenic	0.903
SLC26A4	O43511-1.1	V138W	Pathogenic	0.902
SLC26A4	O43511-1.1	V138Y	Pathogenic	0.893
SLC26A4	O43511-1.1	G139A	Pathogenic	0.989
SLC26A4	O43511-1.1	G139C	Pathogenic	0.996
SLC26A4	O43511-1.1	G139D	Pathogenic	0.982
SLC26A4	O43511-1.1	G139E	Pathogenic	0.98
SLC26A4	O43511-1.1	G139F	Pathogenic	0.952
SLC26A4	O43511-1.1	G139H	Pathogenic	0.976
SLC26A4	O43511-1.1	G139I	Pathogenic	0.985
SLC26A4	O43511-1.1	G139K	Pathogenic	0.931
SLC26A4	O43511-1.1	G139L	Pathogenic	0.985
SLC26A4	O43511-1.1	G139M	Pathogenic	0.976
SLC26A4	O43511-1.1	G139N	Pathogenic	0.957
SLC26A4	O43511-1.1	G139P	Pathogenic	0.991
SLC26A4	O43511-1.1	G139Q	Pathogenic	0.979
SLC26A4	O43511-1.1	G139R	Pathogenic	0.881
SLC26A4	O43511-1.1	G139S	Pathogenic	0.987
SLC26A4	O43511-1.1	G139T	Pathogenic	0.992
SLC26A4	O43511-1.1	G139V	Pathogenic	0.99
SLC26A4	O43511-1.1	G139W	Pathogenic	0.7
SLC26A4	O43511-1.1	G139Y	Pathogenic	0.954
SLC26A4	O43511-1.1	P140A	Pathogenic	0.992
SLC26A4	O43511-1.1	P140C	Pathogenic	0.999
SLC26A4	O43511-1.1	P140D	Pathogenic	0.996
SLC26A4	O43511-1.1	P140E	Pathogenic	0.991
SLC26A4	O43511-1.1	P140F	Pathogenic	0.997
SLC26A4	O43511-1.1	P140G	Pathogenic	0.99
SLC26A4	O43511-1.1	P140H	Pathogenic	0.995
SLC26A4	O43511-1.1	P140I	Pathogenic	0.996
SLC26A4	O43511-1.1	P140K	Pathogenic	0.967
SLC26A4	O43511-1.1	P140L	Pathogenic	0.996
SLC26A4	O43511-1.1	P140M	Pathogenic	0.994
SLC26A4	O43511-1.1	P140N	Pathogenic	0.997
SLC26A4	O43511-1.1	P140Q	Pathogenic	0.99
SLC26A4	O43511-1.1	P140R	Pathogenic	0.97
SLC26A4	O43511-1.1	P140S	Pathogenic	0.993
SLC26A4	O43511-1.1	P140T	Pathogenic	0.997
SLC26A4	O43511-1.1	P140V	Pathogenic	0.997
SLC26A4	O43511-1.1	P140W	Pathogenic	0.986
SLC26A4	O43511-1.1	P140Y	Pathogenic	0.994
SLC26A4	O43511-1.1	F141A	Pathogenic	0.978
SLC26A4	O43511-1.1	F141C	Pathogenic	0.993
SLC26A4	O43511-1.1	F141D	Pathogenic	0.994
SLC26A4	O43511-1.1	F141E	Pathogenic	0.998
SLC26A4	O43511-1.1	F141G	Pathogenic	0.971
SLC26A4	O43511-1.1	F141H	Pathogenic	0.995
SLC26A4	O43511-1.1	F141I	Pathogenic	0.996
SLC26A4	O43511-1.1	F141K	Pathogenic	0.999
SLC26A4	O43511-1.1	F141L	Pathogenic	0.996
SLC26A4	O43511-1.1	F141M	Pathogenic	0.995
SLC26A4	O43511-1.1	F141N	Pathogenic	0.996
SLC26A4	O43511-1.1	F141P	Pathogenic	0.998
SLC26A4	O43511-1.1	F141Q	Pathogenic	0.998
SLC26A4	O43511-1.1	F141R	Pathogenic	0.998
SLC26A4	O43511-1.1	F141S	Pathogenic	0.981
SLC26A4	O43511-1.1	F141T	Pathogenic	0.993
SLC26A4	O43511-1.1	F141V	Pathogenic	0.994
SLC26A4	O43511-1.1	F141W	Pathogenic	0.98
SLC26A4	O43511-1.1	F141Y	Pathogenic	0.966
SLC26A4	O43511-1.1	P142A	Pathogenic	0.995
SLC26A4	O43511-1.1	P142C	Pathogenic	0.999
SLC26A4	O43511-1.1	P142D	Pathogenic	0.997
SLC26A4	O43511-1.1	P142E	Pathogenic	0.994
SLC26A4	O43511-1.1	P142F	Pathogenic	0.998
SLC26A4	O43511-1.1	P142G	Pathogenic	0.993
SLC26A4	O43511-1.1	P142H	Pathogenic	0.996
SLC26A4	O43511-1.1	P142I	Pathogenic	0.997
SLC26A4	O43511-1.1	P142K	Pathogenic	0.977
SLC26A4	O43511-1.1	P142L	Pathogenic	0.997
SLC26A4	O43511-1.1	P142M	Pathogenic	0.995
SLC26A4	O43511-1.1	P142N	Pathogenic	0.998
SLC26A4	O43511-1.1	P142Q	Pathogenic	0.993
SLC26A4	O43511-1.1	P142R	Pathogenic	0.979
SLC26A4	O43511-1.1	P142S	Pathogenic	0.995
SLC26A4	O43511-1.1	P142T	Pathogenic	0.998
SLC26A4	O43511-1.1	P142V	Pathogenic	0.998
SLC26A4	O43511-1.1	P142W	Pathogenic	0.99
SLC26A4	O43511-1.1	P142Y	Pathogenic	0.996
SLC26A4	O43511-1.1	V143A	Pathogenic	0.924
SLC26A4	O43511-1.1	V143C	Pathogenic	0.987
SLC26A4	O43511-1.1	V143D	Pathogenic	0.995
SLC26A4	O43511-1.1	V143E	Pathogenic	0.994
SLC26A4	O43511-1.1	V143F	Pathogenic	0.976
SLC26A4	O43511-1.1	V143G	Pathogenic	0.974
SLC26A4	O43511-1.1	V143H	Pathogenic	0.996
SLC26A4	O43511-1.1	V143I	Pathogenic	0.8
SLC26A4	O43511-1.1	V143K	Pathogenic	0.977
SLC26A4	O43511-1.1	V143L	Pathogenic	0.944
SLC26A4	O43511-1.1	V143M	Pathogenic	0.953
SLC26A4	O43511-1.1	V143N	Pathogenic	0.996
SLC26A4	O43511-1.1	V143P	Pathogenic	0.994
SLC26A4	O43511-1.1	V143Q	Pathogenic	0.993
SLC26A4	O43511-1.1	V143R	Pathogenic	0.979
SLC26A4	O43511-1.1	V143S	Pathogenic	0.983
SLC26A4	O43511-1.1	V143T	Pathogenic	0.975
SLC26A4	O43511-1.1	V143W	Pathogenic	0.974
SLC26A4	O43511-1.1	V143Y	Pathogenic	0.972
SLC26A4	O43511-1.1	V144A	Neutral	0.246
SLC26A4	O43511-1.1	V144C	Pathogenic	0.668
SLC26A4	O43511-1.1	V144D	Pathogenic	0.838
SLC26A4	O43511-1.1	V144E	Pathogenic	0.81
SLC26A4	O43511-1.1	V144F	Pathogenic	0.518
SLC26A4	O43511-1.1	V144G	Neutral	0.5
SLC26A4	O43511-1.1	V144H	Pathogenic	0.884
SLC26A4	O43511-1.1	V144I	Neutral	0.097
SLC26A4	O43511-1.1	V144K	Pathogenic	0.534
SLC26A4	O43511-1.1	V144L	Neutral	0.311
SLC26A4	O43511-1.1	V144M	Neutral	0.351
SLC26A4	O43511-1.1	V144N	Pathogenic	0.874
SLC26A4	O43511-1.1	V144P	Pathogenic	0.814
SLC26A4	O43511-1.1	V144Q	Pathogenic	0.799
SLC26A4	O43511-1.1	V144R	Pathogenic	0.56
SLC26A4	O43511-1.1	V144S	Pathogenic	0.602
SLC26A4	O43511-1.1	V144T	Pathogenic	0.509
SLC26A4	O43511-1.1	V144W	Pathogenic	0.506
SLC26A4	O43511-1.1	V144Y	Neutral	0.48
SLC26A4	O43511-1.1	S145A	Pathogenic	0.979
SLC26A4	O43511-1.1	S145C	Pathogenic	0.991
SLC26A4	O43511-1.1	S145D	Pathogenic	0.979
SLC26A4	O43511-1.1	S145E	Pathogenic	0.956
SLC26A4	O43511-1.1	S145F	Pathogenic	0.944
SLC26A4	O43511-1.1	S145G	Pathogenic	0.978
SLC26A4	O43511-1.1	S145H	Pathogenic	0.972
SLC26A4	O43511-1.1	S145I	Pathogenic	0.965
SLC26A4	O43511-1.1	S145K	Pathogenic	0.855
SLC26A4	O43511-1.1	S145L	Pathogenic	0.967
SLC26A4	O43511-1.1	S145M	Pathogenic	0.945
SLC26A4	O43511-1.1	S145N	Pathogenic	0.952
SLC26A4	O43511-1.1	S145P	Pathogenic	0.99
SLC26A4	O43511-1.1	S145Q	Pathogenic	0.953
SLC26A4	O43511-1.1	S145R	Pathogenic	0.867
SLC26A4	O43511-1.1	S145T	Pathogenic	0.962
SLC26A4	O43511-1.1	S145V	Pathogenic	0.988
SLC26A4	O43511-1.1	S145W	Pathogenic	0.89
SLC26A4	O43511-1.1	S145Y	Pathogenic	0.947
SLC26A4	O43511-1.1	L146A	Neutral	0.475
SLC26A4	O43511-1.1	L146C	Pathogenic	0.735
SLC26A4	O43511-1.1	L146D	Pathogenic	0.935
SLC26A4	O43511-1.1	L146E	Pathogenic	0.944
SLC26A4	O43511-1.1	L146F	Pathogenic	0.856
SLC26A4	O43511-1.1	L146G	Pathogenic	0.735
SLC26A4	O43511-1.1	L146H	Pathogenic	0.972
SLC26A4	O43511-1.1	L146I	Pathogenic	0.707
SLC26A4	O43511-1.1	L146K	Pathogenic	0.898
SLC26A4	O43511-1.1	L146M	Pathogenic	0.676
SLC26A4	O43511-1.1	L146N	Pathogenic	0.905
SLC26A4	O43511-1.1	L146P	Pathogenic	0.924
SLC26A4	O43511-1.1	L146Q	Pathogenic	0.925
SLC26A4	O43511-1.1	L146R	Pathogenic	0.83
SLC26A4	O43511-1.1	L146S	Pathogenic	0.676
SLC26A4	O43511-1.1	L146T	Pathogenic	0.742
SLC26A4	O43511-1.1	L146V	Pathogenic	0.639
SLC26A4	O43511-1.1	L146W	Pathogenic	0.85
SLC26A4	O43511-1.1	L146Y	Pathogenic	0.876
SLC26A4	O43511-1.1	M147A	Pathogenic	0.997
SLC26A4	O43511-1.1	M147C	Pathogenic	0.999
SLC26A4	O43511-1.1	M147D	Pathogenic	1.0
SLC26A4	O43511-1.1	M147E	Pathogenic	1.0
SLC26A4	O43511-1.1	M147F	Pathogenic	0.999
SLC26A4	O43511-1.1	M147G	Pathogenic	0.998
SLC26A4	O43511-1.1	M147H	Pathogenic	1.0
SLC26A4	O43511-1.1	M147I	Pathogenic	0.999
SLC26A4	O43511-1.1	M147K	Pathogenic	0.999
SLC26A4	O43511-1.1	M147L	Pathogenic	0.998
SLC26A4	O43511-1.1	M147N	Pathogenic	0.999
SLC26A4	O43511-1.1	M147P	Pathogenic	1.0
SLC26A4	O43511-1.1	M147Q	Pathogenic	0.999
SLC26A4	O43511-1.1	M147R	Pathogenic	0.999
SLC26A4	O43511-1.1	M147S	Pathogenic	0.997
SLC26A4	O43511-1.1	M147T	Pathogenic	0.999
SLC26A4	O43511-1.1	M147V	Pathogenic	0.998
SLC26A4	O43511-1.1	M147W	Pathogenic	0.999
SLC26A4	O43511-1.1	M147Y	Pathogenic	1.0
SLC26A4	O43511-1.1	V148A	Pathogenic	0.9
SLC26A4	O43511-1.1	V148C	Pathogenic	0.982
SLC26A4	O43511-1.1	V148D	Pathogenic	0.993
SLC26A4	O43511-1.1	V148E	Pathogenic	0.992
SLC26A4	O43511-1.1	V148F	Pathogenic	0.967
SLC26A4	O43511-1.1	V148G	Pathogenic	0.965
SLC26A4	O43511-1.1	V148H	Pathogenic	0.995
SLC26A4	O43511-1.1	V148I	Pathogenic	0.748
SLC26A4	O43511-1.1	V148K	Pathogenic	0.969
SLC26A4	O43511-1.1	V148L	Pathogenic	0.926
SLC26A4	O43511-1.1	V148M	Pathogenic	0.937
SLC26A4	O43511-1.1	V148N	Pathogenic	0.995
SLC26A4	O43511-1.1	V148P	Pathogenic	0.992
SLC26A4	O43511-1.1	V148Q	Pathogenic	0.991
SLC26A4	O43511-1.1	V148R	Pathogenic	0.972
SLC26A4	O43511-1.1	V148S	Pathogenic	0.977
SLC26A4	O43511-1.1	V148T	Pathogenic	0.966
SLC26A4	O43511-1.1	V148W	Pathogenic	0.966
SLC26A4	O43511-1.1	V148Y	Pathogenic	0.962
SLC26A4	O43511-1.1	G149A	Pathogenic	0.992
SLC26A4	O43511-1.1	G149C	Pathogenic	0.997
SLC26A4	O43511-1.1	G149D	Pathogenic	0.986
SLC26A4	O43511-1.1	G149E	Pathogenic	0.985
SLC26A4	O43511-1.1	G149F	Pathogenic	0.963
SLC26A4	O43511-1.1	G149H	Pathogenic	0.981
SLC26A4	O43511-1.1	G149I	Pathogenic	0.988
SLC26A4	O43511-1.1	G149K	Pathogenic	0.946
SLC26A4	O43511-1.1	G149L	Pathogenic	0.989
SLC26A4	O43511-1.1	G149M	Pathogenic	0.981
SLC26A4	O43511-1.1	G149N	Pathogenic	0.967
SLC26A4	O43511-1.1	G149P	Pathogenic	0.993
SLC26A4	O43511-1.1	G149Q	Pathogenic	0.984
SLC26A4	O43511-1.1	G149R	Pathogenic	0.906
SLC26A4	O43511-1.1	G149S	Pathogenic	0.99
SLC26A4	O43511-1.1	G149T	Pathogenic	0.994
SLC26A4	O43511-1.1	G149V	Pathogenic	0.992
SLC26A4	O43511-1.1	G149W	Pathogenic	0.752
SLC26A4	O43511-1.1	G149Y	Pathogenic	0.964
SLC26A4	O43511-1.1	S150A	Neutral	0.472
SLC26A4	O43511-1.1	S150C	Pathogenic	0.67
SLC26A4	O43511-1.1	S150D	Neutral	0.474
SLC26A4	O43511-1.1	S150E	Neutral	0.296
SLC26A4	O43511-1.1	S150F	Neutral	0.247
SLC26A4	O43511-1.1	S150G	Neutral	0.462
SLC26A4	O43511-1.1	S150H	Neutral	0.399
SLC26A4	O43511-1.1	S150I	Neutral	0.349
SLC26A4	O43511-1.1	S150K	Neutral	0.102
SLC26A4	O43511-1.1	S150L	Neutral	0.358
SLC26A4	O43511-1.1	S150M	Neutral	0.249
SLC26A4	O43511-1.1	S150N	Neutral	0.276
SLC26A4	O43511-1.1	S150P	Pathogenic	0.652
SLC26A4	O43511-1.1	S150Q	Neutral	0.283
SLC26A4	O43511-1.1	S150R	Neutral	0.112
SLC26A4	O43511-1.1	S150T	Neutral	0.327
SLC26A4	O43511-1.1	S150V	Pathogenic	0.613
SLC26A4	O43511-1.1	S150W	Neutral	0.135
SLC26A4	O43511-1.1	S150Y	Neutral	0.256
SLC26A4	O43511-1.1	V151A	Pathogenic	0.634
SLC26A4	O43511-1.1	V151C	Pathogenic	0.914
SLC26A4	O43511-1.1	V151D	Pathogenic	0.965
SLC26A4	O43511-1.1	V151E	Pathogenic	0.958
SLC26A4	O43511-1.1	V151F	Pathogenic	0.851
SLC26A4	O43511-1.1	V151G	Pathogenic	0.841
SLC26A4	O43511-1.1	V151H	Pathogenic	0.976
SLC26A4	O43511-1.1	V151I	Neutral	0.363
SLC26A4	O43511-1.1	V151K	Pathogenic	0.859
SLC26A4	O43511-1.1	V151L	Pathogenic	0.706
SLC26A4	O43511-1.1	V151M	Pathogenic	0.742
SLC26A4	O43511-1.1	V151N	Pathogenic	0.973
SLC26A4	O43511-1.1	V151P	Pathogenic	0.959
SLC26A4	O43511-1.1	V151Q	Pathogenic	0.955
SLC26A4	O43511-1.1	V151R	Pathogenic	0.871
SLC26A4	O43511-1.1	V151S	Pathogenic	0.889
SLC26A4	O43511-1.1	V151T	Pathogenic	0.846
SLC26A4	O43511-1.1	V151W	Pathogenic	0.845
SLC26A4	O43511-1.1	V151Y	Pathogenic	0.831
SLC26A4	O43511-1.1	V152A	Pathogenic	0.874
SLC26A4	O43511-1.1	V152C	Pathogenic	0.977
SLC26A4	O43511-1.1	V152D	Pathogenic	0.991
SLC26A4	O43511-1.1	V152E	Pathogenic	0.989
SLC26A4	O43511-1.1	V152F	Pathogenic	0.958
SLC26A4	O43511-1.1	V152G	Pathogenic	0.955
SLC26A4	O43511-1.1	V152H	Pathogenic	0.994
SLC26A4	O43511-1.1	V152I	Pathogenic	0.695
SLC26A4	O43511-1.1	V152K	Pathogenic	0.961
SLC26A4	O43511-1.1	V152L	Pathogenic	0.905
SLC26A4	O43511-1.1	V152M	Pathogenic	0.92
SLC26A4	O43511-1.1	V152N	Pathogenic	0.993
SLC26A4	O43511-1.1	V152P	Pathogenic	0.989
SLC26A4	O43511-1.1	V152Q	Pathogenic	0.988
SLC26A4	O43511-1.1	V152R	Pathogenic	0.964
SLC26A4	O43511-1.1	V152S	Pathogenic	0.97
SLC26A4	O43511-1.1	V152T	Pathogenic	0.956
SLC26A4	O43511-1.1	V152W	Pathogenic	0.956
SLC26A4	O43511-1.1	V152Y	Pathogenic	0.951
SLC26A4	O43511-1.1	L153A	Neutral	0.061
SLC26A4	O43511-1.1	L153C	Neutral	0.166
SLC26A4	O43511-1.1	L153D	Pathogenic	0.508
SLC26A4	O43511-1.1	L153E	Pathogenic	0.549
SLC26A4	O43511-1.1	L153F	Neutral	0.3
SLC26A4	O43511-1.1	L153G	Neutral	0.166
SLC26A4	O43511-1.1	L153H	Pathogenic	0.711
SLC26A4	O43511-1.1	L153I	Neutral	0.148
SLC26A4	O43511-1.1	L153K	Neutral	0.388
SLC26A4	O43511-1.1	L153M	Neutral	0.131
SLC26A4	O43511-1.1	L153N	Neutral	0.407
SLC26A4	O43511-1.1	L153P	Neutral	0.466
SLC26A4	O43511-1.1	L153Q	Neutral	0.472
SLC26A4	O43511-1.1	L153R	Neutral	0.26
SLC26A4	O43511-1.1	L153S	Neutral	0.131
SLC26A4	O43511-1.1	L153T	Neutral	0.172
SLC26A4	O43511-1.1	L153V	Neutral	0.113
SLC26A4	O43511-1.1	L153W	Neutral	0.29
SLC26A4	O43511-1.1	L153Y	Neutral	0.338
SLC26A4	O43511-1.1	S154A	Neutral	0.453
SLC26A4	O43511-1.1	S154C	Pathogenic	0.653
SLC26A4	O43511-1.1	S154D	Neutral	0.455
SLC26A4	O43511-1.1	S154E	Neutral	0.28
SLC26A4	O43511-1.1	S154F	Neutral	0.233
SLC26A4	O43511-1.1	S154G	Neutral	0.443
SLC26A4	O43511-1.1	S154H	Neutral	0.381
SLC26A4	O43511-1.1	S154I	Neutral	0.331
SLC26A4	O43511-1.1	S154K	Neutral	0.095
SLC26A4	O43511-1.1	S154L	Neutral	0.34
SLC26A4	O43511-1.1	S154M	Neutral	0.235
SLC26A4	O43511-1.1	S154N	Neutral	0.261
SLC26A4	O43511-1.1	S154P	Pathogenic	0.635
SLC26A4	O43511-1.1	S154Q	Neutral	0.267
SLC26A4	O43511-1.1	S154R	Neutral	0.105
SLC26A4	O43511-1.1	S154T	Neutral	0.31
SLC26A4	O43511-1.1	S154V	Pathogenic	0.594
SLC26A4	O43511-1.1	S154W	Neutral	0.126
SLC26A4	O43511-1.1	S154Y	Neutral	0.241
SLC26A4	O43511-1.1	M155A	Pathogenic	0.685
SLC26A4	O43511-1.1	M155C	Pathogenic	0.869
SLC26A4	O43511-1.1	M155D	Pathogenic	0.945
SLC26A4	O43511-1.1	M155E	Pathogenic	0.953
SLC26A4	O43511-1.1	M155F	Pathogenic	0.908
SLC26A4	O43511-1.1	M155G	Pathogenic	0.767
SLC26A4	O43511-1.1	M155H	Pathogenic	0.976
SLC26A4	O43511-1.1	M155I	Pathogenic	0.89
SLC26A4	O43511-1.1	M155K	Pathogenic	0.913
SLC26A4	O43511-1.1	M155L	Pathogenic	0.807
SLC26A4	O43511-1.1	M155N	Pathogenic	0.919
SLC26A4	O43511-1.1	M155P	Pathogenic	0.935
SLC26A4	O43511-1.1	M155Q	Pathogenic	0.88
SLC26A4	O43511-1.1	M155R	Pathogenic	0.853
SLC26A4	O43511-1.1	M155S	Pathogenic	0.714
SLC26A4	O43511-1.1	M155T	Pathogenic	0.873
SLC26A4	O43511-1.1	M155V	Pathogenic	0.809
SLC26A4	O43511-1.1	M155W	Pathogenic	0.825
SLC26A4	O43511-1.1	M155Y	Pathogenic	0.944
SLC26A4	O43511-1.1	A156C	Pathogenic	0.587
SLC26A4	O43511-1.1	A156D	Pathogenic	0.797
SLC26A4	O43511-1.1	A156E	Neutral	0.477
SLC26A4	O43511-1.1	A156F	Neutral	0.316
SLC26A4	O43511-1.1	A156G	Pathogenic	0.621
SLC26A4	O43511-1.1	A156H	Pathogenic	0.622
SLC26A4	O43511-1.1	A156I	Neutral	0.273
SLC26A4	O43511-1.1	A156K	Neutral	0.198
SLC26A4	O43511-1.1	A156L	Neutral	0.281
SLC26A4	O43511-1.1	A156M	Neutral	0.319
SLC26A4	O43511-1.1	A156N	Pathogenic	0.77
SLC26A4	O43511-1.1	A156P	Pathogenic	0.726
SLC26A4	O43511-1.1	A156Q	Neutral	0.461
SLC26A4	O43511-1.1	A156R	Neutral	0.12
SLC26A4	O43511-1.1	A156S	Pathogenic	0.591
SLC26A4	O43511-1.1	A156T	Pathogenic	0.569
SLC26A4	O43511-1.1	A156V	Neutral	0.356
SLC26A4	O43511-1.1	A156W	Neutral	0.18
SLC26A4	O43511-1.1	A156Y	Neutral	0.326
SLC26A4	O43511-1.1	P157A	Pathogenic	0.993
SLC26A4	O43511-1.1	P157C	Pathogenic	0.999
SLC26A4	O43511-1.1	P157D	Pathogenic	0.996
SLC26A4	O43511-1.1	P157E	Pathogenic	0.992
SLC26A4	O43511-1.1	P157F	Pathogenic	0.997
SLC26A4	O43511-1.1	P157G	Pathogenic	0.991
SLC26A4	O43511-1.1	P157H	Pathogenic	0.996
SLC26A4	O43511-1.1	P157I	Pathogenic	0.996
SLC26A4	O43511-1.1	P157K	Pathogenic	0.971
SLC26A4	O43511-1.1	P157L	Pathogenic	0.997
SLC26A4	O43511-1.1	P157M	Pathogenic	0.994
SLC26A4	O43511-1.1	P157N	Pathogenic	0.998
SLC26A4	O43511-1.1	P157Q	Pathogenic	0.991
SLC26A4	O43511-1.1	P157R	Pathogenic	0.974
SLC26A4	O43511-1.1	P157S	Pathogenic	0.994
SLC26A4	O43511-1.1	P157T	Pathogenic	0.997
SLC26A4	O43511-1.1	P157V	Pathogenic	0.998
SLC26A4	O43511-1.1	P157W	Pathogenic	0.988
SLC26A4	O43511-1.1	P157Y	Pathogenic	0.995
SLC26A4	O43511-1.1	D158A	Pathogenic	0.989
SLC26A4	O43511-1.1	D158C	Pathogenic	0.997
SLC26A4	O43511-1.1	D158E	Pathogenic	0.911
SLC26A4	O43511-1.1	D158F	Pathogenic	0.976
SLC26A4	O43511-1.1	D158G	Pathogenic	0.955
SLC26A4	O43511-1.1	D158H	Pathogenic	0.976
SLC26A4	O43511-1.1	D158I	Pathogenic	0.985
SLC26A4	O43511-1.1	D158K	Pathogenic	0.961
SLC26A4	O43511-1.1	D158L	Pathogenic	0.993
SLC26A4	O43511-1.1	D158M	Pathogenic	0.988
SLC26A4	O43511-1.1	D158N	Pathogenic	0.973
SLC26A4	O43511-1.1	D158P	Pathogenic	0.991
SLC26A4	O43511-1.1	D158Q	Pathogenic	0.966
SLC26A4	O43511-1.1	D158R	Pathogenic	0.965
SLC26A4	O43511-1.1	D158S	Pathogenic	0.971
SLC26A4	O43511-1.1	D158T	Pathogenic	0.992
SLC26A4	O43511-1.1	D158V	Pathogenic	0.995
SLC26A4	O43511-1.1	D158W	Pathogenic	0.951
SLC26A4	O43511-1.1	D158Y	Pathogenic	0.977
SLC26A4	O43511-1.1	E159A	Neutral	0.346
SLC26A4	O43511-1.1	E159C	Pathogenic	0.886
SLC26A4	O43511-1.1	E159D	Neutral	0.208
SLC26A4	O43511-1.1	E159F	Pathogenic	0.713
SLC26A4	O43511-1.1	E159G	Neutral	0.336
SLC26A4	O43511-1.1	E159H	Pathogenic	0.555
SLC26A4	O43511-1.1	E159I	Pathogenic	0.802
SLC26A4	O43511-1.1	E159K	Neutral	0.253
SLC26A4	O43511-1.1	E159L	Pathogenic	0.808
SLC26A4	O43511-1.1	E159M	Pathogenic	0.715
SLC26A4	O43511-1.1	E159N	Pathogenic	0.58
SLC26A4	O43511-1.1	E159P	Pathogenic	0.56
SLC26A4	O43511-1.1	E159Q	Neutral	0.298
SLC26A4	O43511-1.1	E159R	Neutral	0.273
SLC26A4	O43511-1.1	E159S	Neutral	0.282
SLC26A4	O43511-1.1	E159T	Pathogenic	0.635
SLC26A4	O43511-1.1	E159V	Pathogenic	0.806
SLC26A4	O43511-1.1	E159W	Neutral	0.37
SLC26A4	O43511-1.1	E159Y	Pathogenic	0.564
SLC26A4	O43511-1.1	H160A	Neutral	0.479
SLC26A4	O43511-1.1	H160C	Pathogenic	0.77
SLC26A4	O43511-1.1	H160D	Pathogenic	0.505
SLC26A4	O43511-1.1	H160E	Pathogenic	0.547
SLC26A4	O43511-1.1	H160F	Pathogenic	0.545
SLC26A4	O43511-1.1	H160G	Neutral	0.284
SLC26A4	O43511-1.1	H160I	Pathogenic	0.888
SLC26A4	O43511-1.1	H160K	Pathogenic	0.596
SLC26A4	O43511-1.1	H160L	Pathogenic	0.892
SLC26A4	O43511-1.1	H160M	Pathogenic	0.831
SLC26A4	O43511-1.1	H160N	Neutral	0.253
SLC26A4	O43511-1.1	H160P	Pathogenic	0.689
SLC26A4	O43511-1.1	H160Q	Pathogenic	0.64
SLC26A4	O43511-1.1	H160R	Neutral	0.289
SLC26A4	O43511-1.1	H160S	Neutral	0.375
SLC26A4	O43511-1.1	H160T	Pathogenic	0.752
SLC26A4	O43511-1.1	H160V	Pathogenic	0.878
SLC26A4	O43511-1.1	H160W	Neutral	0.363
SLC26A4	O43511-1.1	H160Y	Neutral	0.134
SLC26A4	O43511-1.1	F161A	Neutral	0.178
SLC26A4	O43511-1.1	F161C	Neutral	0.399
SLC26A4	O43511-1.1	F161D	Neutral	0.46
SLC26A4	O43511-1.1	F161E	Pathogenic	0.669
SLC26A4	O43511-1.1	F161G	Neutral	0.141
SLC26A4	O43511-1.1	F161H	Pathogenic	0.502
SLC26A4	O43511-1.1	F161I	Pathogenic	0.554
SLC26A4	O43511-1.1	F161K	Pathogenic	0.851
SLC26A4	O43511-1.1	F161L	Pathogenic	0.547
SLC26A4	O43511-1.1	F161M	Pathogenic	0.502
SLC26A4	O43511-1.1	F161N	Pathogenic	0.532
SLC26A4	O43511-1.1	F161P	Pathogenic	0.744
SLC26A4	O43511-1.1	F161Q	Pathogenic	0.748
SLC26A4	O43511-1.1	F161R	Pathogenic	0.759
SLC26A4	O43511-1.1	F161S	Neutral	0.2
SLC26A4	O43511-1.1	F161T	Neutral	0.408
SLC26A4	O43511-1.1	F161V	Neutral	0.46
SLC26A4	O43511-1.1	F161W	Neutral	0.194
SLC26A4	O43511-1.1	F161Y	Neutral	0.123
SLC26A4	O43511-1.1	L162A	Neutral	0.017
SLC26A4	O43511-1.1	L162C	Neutral	0.049
SLC26A4	O43511-1.1	L162D	Neutral	0.212
SLC26A4	O43511-1.1	L162E	Neutral	0.241
SLC26A4	O43511-1.1	L162F	Neutral	0.1
SLC26A4	O43511-1.1	L162G	Neutral	0.049
SLC26A4	O43511-1.1	L162H	Neutral	0.39
SLC26A4	O43511-1.1	L162I	Neutral	0.043
SLC26A4	O43511-1.1	L162K	Neutral	0.142
SLC26A4	O43511-1.1	L162M	Neutral	0.038
SLC26A4	O43511-1.1	L162N	Neutral	0.152
SLC26A4	O43511-1.1	L162P	Neutral	0.185
SLC26A4	O43511-1.1	L162Q	Neutral	0.188
SLC26A4	O43511-1.1	L162R	Neutral	0.084
SLC26A4	O43511-1.1	L162S	Neutral	0.038
SLC26A4	O43511-1.1	L162T	Neutral	0.051
SLC26A4	O43511-1.1	L162V	Neutral	0.032
SLC26A4	O43511-1.1	L162W	Neutral	0.096
SLC26A4	O43511-1.1	L162Y	Neutral	0.117
SLC26A4	O43511-1.1	V163A	Neutral	0.002
SLC26A4	O43511-1.1	V163C	Neutral	0.012
SLC26A4	O43511-1.1	V163D	Neutral	0.031
SLC26A4	O43511-1.1	V163E	Neutral	0.026
SLC26A4	O43511-1.1	V163F	Neutral	0.007
SLC26A4	O43511-1.1	V163G	Neutral	0.006
SLC26A4	O43511-1.1	V163H	Neutral	0.046
SLC26A4	O43511-1.1	V163I	Neutral	0.001
SLC26A4	O43511-1.1	V163K	Neutral	0.007
SLC26A4	O43511-1.1	V163L	Neutral	0.003
SLC26A4	O43511-1.1	V163M	Neutral	0.003
SLC26A4	O43511-1.1	V163N	Neutral	0.041
SLC26A4	O43511-1.1	V163P	Neutral	0.027
SLC26A4	O43511-1.1	V163Q	Neutral	0.024
SLC26A4	O43511-1.1	V163R	Neutral	0.008
SLC26A4	O43511-1.1	V163S	Neutral	0.009
SLC26A4	O43511-1.1	V163T	Neutral	0.006
SLC26A4	O43511-1.1	V163W	Neutral	0.006
SLC26A4	O43511-1.1	V163Y	Neutral	0.006
SLC26A4	O43511-1.1	S164A	Neutral	0.056
SLC26A4	O43511-1.1	S164C	Neutral	0.118
SLC26A4	O43511-1.1	S164D	Neutral	0.056
SLC26A4	O43511-1.1	S164E	Neutral	0.027
SLC26A4	O43511-1.1	S164F	Neutral	0.021
SLC26A4	O43511-1.1	S164G	Neutral	0.054
SLC26A4	O43511-1.1	S164H	Neutral	0.042
SLC26A4	O43511-1.1	S164I	Neutral	0.034
SLC26A4	O43511-1.1	S164K	Neutral	0.007
SLC26A4	O43511-1.1	S164L	Neutral	0.035
SLC26A4	O43511-1.1	S164M	Neutral	0.021
SLC26A4	O43511-1.1	S164N	Neutral	0.025
SLC26A4	O43511-1.1	S164P	Neutral	0.11
SLC26A4	O43511-1.1	S164Q	Neutral	0.025
SLC26A4	O43511-1.1	S164R	Neutral	0.008
SLC26A4	O43511-1.1	S164T	Neutral	0.031
SLC26A4	O43511-1.1	S164V	Neutral	0.095
SLC26A4	O43511-1.1	S164W	Neutral	0.01
SLC26A4	O43511-1.1	S164Y	Neutral	0.022
SLC26A4	O43511-1.1	S165A	Neutral	0.077
SLC26A4	O43511-1.1	S165C	Neutral	0.159
SLC26A4	O43511-1.1	S165D	Neutral	0.077
SLC26A4	O43511-1.1	S165E	Neutral	0.038
SLC26A4	O43511-1.1	S165F	Neutral	0.03
SLC26A4	O43511-1.1	S165G	Neutral	0.074
SLC26A4	O43511-1.1	S165H	Neutral	0.058
SLC26A4	O43511-1.1	S165I	Neutral	0.047
SLC26A4	O43511-1.1	S165K	Neutral	0.01
SLC26A4	O43511-1.1	S165L	Neutral	0.049
SLC26A4	O43511-1.1	S165M	Neutral	0.03
SLC26A4	O43511-1.1	S165N	Neutral	0.034
SLC26A4	O43511-1.1	S165P	Neutral	0.149
SLC26A4	O43511-1.1	S165Q	Neutral	0.035
SLC26A4	O43511-1.1	S165R	Neutral	0.012
SLC26A4	O43511-1.1	S165T	Neutral	0.043
SLC26A4	O43511-1.1	S165V	Neutral	0.128
SLC26A4	O43511-1.1	S165W	Neutral	0.014
SLC26A4	O43511-1.1	S165Y	Neutral	0.031
SLC26A4	O43511-1.1	S166A	Neutral	0.172
SLC26A4	O43511-1.1	S166C	Neutral	0.321
SLC26A4	O43511-1.1	S166D	Neutral	0.173
SLC26A4	O43511-1.1	S166E	Neutral	0.089
SLC26A4	O43511-1.1	S166F	Neutral	0.071
SLC26A4	O43511-1.1	S166G	Neutral	0.167
SLC26A4	O43511-1.1	S166H	Neutral	0.134
SLC26A4	O43511-1.1	S166I	Neutral	0.111
SLC26A4	O43511-1.1	S166K	Neutral	0.026
SLC26A4	O43511-1.1	S166L	Neutral	0.115
SLC26A4	O43511-1.1	S166M	Neutral	0.072
SLC26A4	O43511-1.1	S166N	Neutral	0.082
SLC26A4	O43511-1.1	S166P	Neutral	0.304
SLC26A4	O43511-1.1	S166Q	Neutral	0.084
SLC26A4	O43511-1.1	S166R	Neutral	0.029
SLC26A4	O43511-1.1	S166T	Neutral	0.101
SLC26A4	O43511-1.1	S166V	Neutral	0.269
SLC26A4	O43511-1.1	S166W	Neutral	0.035
SLC26A4	O43511-1.1	S166Y	Neutral	0.074
SLC26A4	O43511-1.1	N167A	Pathogenic	0.981
SLC26A4	O43511-1.1	N167C	Pathogenic	0.995
SLC26A4	O43511-1.1	N167D	Pathogenic	0.962
SLC26A4	O43511-1.1	N167E	Pathogenic	0.974
SLC26A4	O43511-1.1	N167F	Pathogenic	0.974
SLC26A4	O43511-1.1	N167G	Pathogenic	0.862
SLC26A4	O43511-1.1	N167H	Pathogenic	0.905
SLC26A4	O43511-1.1	N167I	Pathogenic	0.984
SLC26A4	O43511-1.1	N167K	Pathogenic	0.91
SLC26A4	O43511-1.1	N167L	Pathogenic	0.985
SLC26A4	O43511-1.1	N167M	Pathogenic	0.975
SLC26A4	O43511-1.1	N167P	Pathogenic	0.992
SLC26A4	O43511-1.1	N167Q	Pathogenic	0.963
SLC26A4	O43511-1.1	N167R	Pathogenic	0.849
SLC26A4	O43511-1.1	N167S	Pathogenic	0.907
SLC26A4	O43511-1.1	N167T	Pathogenic	0.977
SLC26A4	O43511-1.1	N167V	Pathogenic	0.995
SLC26A4	O43511-1.1	N167W	Pathogenic	0.948
SLC26A4	O43511-1.1	N167Y	Pathogenic	0.952
SLC26A4	O43511-1.1	G168A	Neutral	0.444
SLC26A4	O43511-1.1	G168C	Pathogenic	0.679
SLC26A4	O43511-1.1	G168D	Neutral	0.312
SLC26A4	O43511-1.1	G168E	Neutral	0.298
SLC26A4	O43511-1.1	G168F	Neutral	0.145
SLC26A4	O43511-1.1	G168H	Neutral	0.256
SLC26A4	O43511-1.1	G168I	Neutral	0.358
SLC26A4	O43511-1.1	G168K	Neutral	0.103
SLC26A4	O43511-1.1	G168L	Neutral	0.367
SLC26A4	O43511-1.1	G168M	Neutral	0.257
SLC26A4	O43511-1.1	G168N	Neutral	0.161
SLC26A4	O43511-1.1	G168P	Neutral	0.493
SLC26A4	O43511-1.1	G168Q	Neutral	0.285
SLC26A4	O43511-1.1	G168R	Neutral	0.06
SLC26A4	O43511-1.1	G168S	Neutral	0.403
SLC26A4	O43511-1.1	G168T	Pathogenic	0.504
SLC26A4	O43511-1.1	G168V	Neutral	0.45
SLC26A4	O43511-1.1	G168W	Neutral	0.02
SLC26A4	O43511-1.1	G168Y	Neutral	0.151
SLC26A4	O43511-1.1	T169A	Pathogenic	0.776
SLC26A4	O43511-1.1	T169C	Pathogenic	0.927
SLC26A4	O43511-1.1	T169D	Pathogenic	0.934
SLC26A4	O43511-1.1	T169E	Pathogenic	0.888
SLC26A4	O43511-1.1	T169F	Pathogenic	0.794
SLC26A4	O43511-1.1	T169G	Pathogenic	0.846
SLC26A4	O43511-1.1	T169H	Pathogenic	0.934
SLC26A4	O43511-1.1	T169I	Pathogenic	0.758
SLC26A4	O43511-1.1	T169K	Pathogenic	0.681
SLC26A4	O43511-1.1	T169L	Pathogenic	0.765
SLC26A4	O43511-1.1	T169M	Pathogenic	0.796
SLC26A4	O43511-1.1	T169N	Pathogenic	0.878
SLC26A4	O43511-1.1	T169P	Pathogenic	0.944
SLC26A4	O43511-1.1	T169Q	Pathogenic	0.881
SLC26A4	O43511-1.1	T169R	Pathogenic	0.542
SLC26A4	O43511-1.1	T169S	Pathogenic	0.674
SLC26A4	O43511-1.1	T169V	Pathogenic	0.822
SLC26A4	O43511-1.1	T169W	Neutral	0.476
SLC26A4	O43511-1.1	T169Y	Pathogenic	0.802
SLC26A4	O43511-1.1	V170A	Neutral	0.001
SLC26A4	O43511-1.1	V170C	Neutral	0.004
SLC26A4	O43511-1.1	V170D	Neutral	0.01
SLC26A4	O43511-1.1	V170E	Neutral	0.008
SLC26A4	O43511-1.1	V170F	Neutral	0.002
SLC26A4	O43511-1.1	V170G	Neutral	0.002
SLC26A4	O43511-1.1	V170H	Neutral	0.015
SLC26A4	O43511-1.1	V170I	Neutral	0.0
SLC26A4	O43511-1.1	V170K	Neutral	0.002
SLC26A4	O43511-1.1	V170L	Neutral	0.001
SLC26A4	O43511-1.1	V170M	Neutral	0.001
SLC26A4	O43511-1.1	V170N	Neutral	0.014
SLC26A4	O43511-1.1	V170P	Neutral	0.009
SLC26A4	O43511-1.1	V170Q	Neutral	0.008
SLC26A4	O43511-1.1	V170R	Neutral	0.003
SLC26A4	O43511-1.1	V170S	Neutral	0.003
SLC26A4	O43511-1.1	V170T	Neutral	0.002
SLC26A4	O43511-1.1	V170W	Neutral	0.002
SLC26A4	O43511-1.1	V170Y	Neutral	0.002
SLC26A4	O43511-1.1	L171A	Neutral	0.003
SLC26A4	O43511-1.1	L171C	Neutral	0.009
SLC26A4	O43511-1.1	L171D	Neutral	0.045
SLC26A4	O43511-1.1	L171E	Neutral	0.053
SLC26A4	O43511-1.1	L171F	Neutral	0.019
SLC26A4	O43511-1.1	L171G	Neutral	0.009
SLC26A4	O43511-1.1	L171H	Neutral	0.101
SLC26A4	O43511-1.1	L171I	Neutral	0.008
SLC26A4	O43511-1.1	L171K	Neutral	0.028
SLC26A4	O43511-1.1	L171M	Neutral	0.007
SLC26A4	O43511-1.1	L171N	Neutral	0.03
SLC26A4	O43511-1.1	L171P	Neutral	0.038
SLC26A4	O43511-1.1	L171Q	Neutral	0.039
SLC26A4	O43511-1.1	L171R	Neutral	0.016
SLC26A4	O43511-1.1	L171S	Neutral	0.007
SLC26A4	O43511-1.1	L171T	Neutral	0.009
SLC26A4	O43511-1.1	L171V	Neutral	0.006
SLC26A4	O43511-1.1	L171W	Neutral	0.018
SLC26A4	O43511-1.1	L171Y	Neutral	0.023
SLC26A4	O43511-1.1	N172A	Pathogenic	0.992
SLC26A4	O43511-1.1	N172C	Pathogenic	0.998
SLC26A4	O43511-1.1	N172D	Pathogenic	0.983
SLC26A4	O43511-1.1	N172E	Pathogenic	0.988
SLC26A4	O43511-1.1	N172F	Pathogenic	0.988
SLC26A4	O43511-1.1	N172G	Pathogenic	0.933
SLC26A4	O43511-1.1	N172H	Pathogenic	0.955
SLC26A4	O43511-1.1	N172I	Pathogenic	0.993
SLC26A4	O43511-1.1	N172K	Pathogenic	0.958
SLC26A4	O43511-1.1	N172L	Pathogenic	0.993
SLC26A4	O43511-1.1	N172M	Pathogenic	0.989
SLC26A4	O43511-1.1	N172P	Pathogenic	0.996
SLC26A4	O43511-1.1	N172Q	Pathogenic	0.983
SLC26A4	O43511-1.1	N172R	Pathogenic	0.926
SLC26A4	O43511-1.1	N172S	Pathogenic	0.956
SLC26A4	O43511-1.1	N172T	Pathogenic	0.99
SLC26A4	O43511-1.1	N172V	Pathogenic	0.998
SLC26A4	O43511-1.1	N172W	Pathogenic	0.976
SLC26A4	O43511-1.1	N172Y	Pathogenic	0.978
SLC26A4	O43511-1.1	T173A	Neutral	0.053
SLC26A4	O43511-1.1	T173C	Neutral	0.169
SLC26A4	O43511-1.1	T173D	Neutral	0.184
SLC26A4	O43511-1.1	T173E	Neutral	0.112
SLC26A4	O43511-1.1	T173F	Neutral	0.058
SLC26A4	O43511-1.1	T173G	Neutral	0.081
SLC26A4	O43511-1.1	T173H	Neutral	0.186
SLC26A4	O43511-1.1	T173I	Neutral	0.048
SLC26A4	O43511-1.1	T173K	Neutral	0.033
SLC26A4	O43511-1.1	T173L	Neutral	0.049
SLC26A4	O43511-1.1	T173M	Neutral	0.059
SLC26A4	O43511-1.1	T173N	Neutral	0.103
SLC26A4	O43511-1.1	T173P	Neutral	0.212
SLC26A4	O43511-1.1	T173Q	Neutral	0.106
SLC26A4	O43511-1.1	T173R	Neutral	0.019
SLC26A4	O43511-1.1	T173S	Neutral	0.032
SLC26A4	O43511-1.1	T173V	Neutral	0.069
SLC26A4	O43511-1.1	T173W	Neutral	0.014
SLC26A4	O43511-1.1	T173Y	Neutral	0.061
SLC26A4	O43511-1.1	T174A	Pathogenic	0.791
SLC26A4	O43511-1.1	T174C	Pathogenic	0.933
SLC26A4	O43511-1.1	T174D	Pathogenic	0.939
SLC26A4	O43511-1.1	T174E	Pathogenic	0.896
SLC26A4	O43511-1.1	T174F	Pathogenic	0.807
SLC26A4	O43511-1.1	T174G	Pathogenic	0.857
SLC26A4	O43511-1.1	T174H	Pathogenic	0.94
SLC26A4	O43511-1.1	T174I	Pathogenic	0.773
SLC26A4	O43511-1.1	T174K	Pathogenic	0.7
SLC26A4	O43511-1.1	T174L	Pathogenic	0.78
SLC26A4	O43511-1.1	T174M	Pathogenic	0.81
SLC26A4	O43511-1.1	T174N	Pathogenic	0.887
SLC26A4	O43511-1.1	T174P	Pathogenic	0.948
SLC26A4	O43511-1.1	T174Q	Pathogenic	0.89
SLC26A4	O43511-1.1	T174R	Pathogenic	0.563
SLC26A4	O43511-1.1	T174S	Pathogenic	0.692
SLC26A4	O43511-1.1	T174V	Pathogenic	0.834
SLC26A4	O43511-1.1	T174W	Neutral	0.498
SLC26A4	O43511-1.1	T174Y	Pathogenic	0.815
SLC26A4	O43511-1.1	M175A	Neutral	0.122
SLC26A4	O43511-1.1	M175C	Neutral	0.298
SLC26A4	O43511-1.1	M175D	Pathogenic	0.522
SLC26A4	O43511-1.1	M175E	Pathogenic	0.563
SLC26A4	O43511-1.1	M175F	Neutral	0.388
SLC26A4	O43511-1.1	M175G	Neutral	0.174
SLC26A4	O43511-1.1	M175H	Pathogenic	0.723
SLC26A4	O43511-1.1	M175I	Neutral	0.341
SLC26A4	O43511-1.1	M175K	Neutral	0.402
SLC26A4	O43511-1.1	M175L	Neutral	0.211
SLC26A4	O43511-1.1	M175N	Neutral	0.421
SLC26A4	O43511-1.1	M175P	Neutral	0.48
SLC26A4	O43511-1.1	M175Q	Neutral	0.32
SLC26A4	O43511-1.1	M175R	Neutral	0.271
SLC26A4	O43511-1.1	M175S	Neutral	0.138
SLC26A4	O43511-1.1	M175T	Neutral	0.306
SLC26A4	O43511-1.1	M175V	Neutral	0.214
SLC26A4	O43511-1.1	M175W	Neutral	0.232
SLC26A4	O43511-1.1	M175Y	Pathogenic	0.521
SLC26A4	O43511-1.1	I176A	Neutral	0.048
SLC26A4	O43511-1.1	I176C	Neutral	0.134
SLC26A4	O43511-1.1	I176D	Neutral	0.285
SLC26A4	O43511-1.1	I176E	Neutral	0.486
SLC26A4	O43511-1.1	I176F	Neutral	0.262
SLC26A4	O43511-1.1	I176G	Neutral	0.134
SLC26A4	O43511-1.1	I176H	Pathogenic	0.656
SLC26A4	O43511-1.1	I176K	Neutral	0.497
SLC26A4	O43511-1.1	I176L	Neutral	0.123
SLC26A4	O43511-1.1	I176M	Neutral	0.19
SLC26A4	O43511-1.1	I176N	Neutral	0.348
SLC26A4	O43511-1.1	I176P	Neutral	0.403
SLC26A4	O43511-1.1	I176Q	Pathogenic	0.582
SLC26A4	O43511-1.1	I176R	Neutral	0.353
SLC26A4	O43511-1.1	I176S	Neutral	0.105
SLC26A4	O43511-1.1	I176T	Neutral	0.138
SLC26A4	O43511-1.1	I176V	Neutral	0.024
SLC26A4	O43511-1.1	I176W	Neutral	0.408
SLC26A4	O43511-1.1	I176Y	Neutral	0.284
SLC26A4	O43511-1.1	D177A	Pathogenic	0.781
SLC26A4	O43511-1.1	D177C	Pathogenic	0.929
SLC26A4	O43511-1.1	D177E	Neutral	0.292
SLC26A4	O43511-1.1	D177F	Pathogenic	0.621
SLC26A4	O43511-1.1	D177G	Neutral	0.459
SLC26A4	O43511-1.1	D177H	Pathogenic	0.624
SLC26A4	O43511-1.1	D177I	Pathogenic	0.728
SLC26A4	O43511-1.1	D177K	Pathogenic	0.5
SLC26A4	O43511-1.1	D177L	Pathogenic	0.849
SLC26A4	O43511-1.1	D177M	Pathogenic	0.77
SLC26A4	O43511-1.1	D177N	Pathogenic	0.595
SLC26A4	O43511-1.1	D177P	Pathogenic	0.811
SLC26A4	O43511-1.1	D177Q	Pathogenic	0.531
SLC26A4	O43511-1.1	D177R	Pathogenic	0.527
SLC26A4	O43511-1.1	D177S	Pathogenic	0.569
SLC26A4	O43511-1.1	D177T	Pathogenic	0.83
SLC26A4	O43511-1.1	D177V	Pathogenic	0.888
SLC26A4	O43511-1.1	D177W	Neutral	0.438
SLC26A4	O43511-1.1	D177Y	Pathogenic	0.633
SLC26A4	O43511-1.1	T178A	Neutral	0.034
SLC26A4	O43511-1.1	T178C	Neutral	0.114
SLC26A4	O43511-1.1	T178D	Neutral	0.125
SLC26A4	O43511-1.1	T178E	Neutral	0.074
SLC26A4	O43511-1.1	T178F	Neutral	0.037
SLC26A4	O43511-1.1	T178G	Neutral	0.053
SLC26A4	O43511-1.1	T178H	Neutral	0.126
SLC26A4	O43511-1.1	T178I	Neutral	0.031
SLC26A4	O43511-1.1	T178K	Neutral	0.021
SLC26A4	O43511-1.1	T178L	Neutral	0.032
SLC26A4	O43511-1.1	T178M	Neutral	0.038
SLC26A4	O43511-1.1	T178N	Neutral	0.068
SLC26A4	O43511-1.1	T178P	Neutral	0.145
SLC26A4	O43511-1.1	T178Q	Neutral	0.07
SLC26A4	O43511-1.1	T178R	Neutral	0.012
SLC26A4	O43511-1.1	T178S	Neutral	0.02
SLC26A4	O43511-1.1	T178V	Neutral	0.044
SLC26A4	O43511-1.1	T178W	Neutral	0.009
SLC26A4	O43511-1.1	T178Y	Neutral	0.039
SLC26A4	O43511-1.1	A179C	Neutral	0.016
SLC26A4	O43511-1.1	A179D	Neutral	0.042
SLC26A4	O43511-1.1	A179E	Neutral	0.01
SLC26A4	O43511-1.1	A179F	Neutral	0.005
SLC26A4	O43511-1.1	A179G	Neutral	0.018
SLC26A4	O43511-1.1	A179H	Neutral	0.018
SLC26A4	O43511-1.1	A179I	Neutral	0.004
SLC26A4	O43511-1.1	A179K	Neutral	0.003
SLC26A4	O43511-1.1	A179L	Neutral	0.004
SLC26A4	O43511-1.1	A179M	Neutral	0.005
SLC26A4	O43511-1.1	A179N	Neutral	0.036
SLC26A4	O43511-1.1	A179P	Neutral	0.029
SLC26A4	O43511-1.1	A179Q	Neutral	0.01
SLC26A4	O43511-1.1	A179R	Neutral	0.002
SLC26A4	O43511-1.1	A179S	Neutral	0.016
SLC26A4	O43511-1.1	A179T	Neutral	0.015
SLC26A4	O43511-1.1	A179V	Neutral	0.006
SLC26A4	O43511-1.1	A179W	Neutral	0.002
SLC26A4	O43511-1.1	A179Y	Neutral	0.005
SLC26A4	O43511-1.1	A180C	Neutral	0.236
SLC26A4	O43511-1.1	A180D	Neutral	0.46
SLC26A4	O43511-1.1	A180E	Neutral	0.165
SLC26A4	O43511-1.1	A180F	Neutral	0.091
SLC26A4	O43511-1.1	A180G	Neutral	0.263
SLC26A4	O43511-1.1	A180H	Neutral	0.263
SLC26A4	O43511-1.1	A180I	Neutral	0.075
SLC26A4	O43511-1.1	A180K	Neutral	0.051
SLC26A4	O43511-1.1	A180L	Neutral	0.078
SLC26A4	O43511-1.1	A180M	Neutral	0.092
SLC26A4	O43511-1.1	A180N	Neutral	0.421
SLC26A4	O43511-1.1	A180P	Neutral	0.365
SLC26A4	O43511-1.1	A180Q	Neutral	0.157
SLC26A4	O43511-1.1	A180R	Neutral	0.029
SLC26A4	O43511-1.1	A180S	Neutral	0.239
SLC26A4	O43511-1.1	A180T	Neutral	0.223
SLC26A4	O43511-1.1	A180V	Neutral	0.107
SLC26A4	O43511-1.1	A180W	Neutral	0.045
SLC26A4	O43511-1.1	A180Y	Neutral	0.095
SLC26A4	O43511-1.1	R181A	Neutral	0.21
SLC26A4	O43511-1.1	R181C	Pathogenic	0.661
SLC26A4	O43511-1.1	R181D	Pathogenic	0.705
SLC26A4	O43511-1.1	R181E	Pathogenic	0.559
SLC26A4	O43511-1.1	R181F	Pathogenic	0.929
SLC26A4	O43511-1.1	R181G	Neutral	0.203
SLC26A4	O43511-1.1	R181H	Pathogenic	0.586
SLC26A4	O43511-1.1	R181I	Pathogenic	0.888
SLC26A4	O43511-1.1	R181K	Pathogenic	0.538
SLC26A4	O43511-1.1	R181L	Pathogenic	0.804
SLC26A4	O43511-1.1	R181M	Pathogenic	0.709
SLC26A4	O43511-1.1	R181N	Neutral	0.41
SLC26A4	O43511-1.1	R181P	Pathogenic	0.563
SLC26A4	O43511-1.1	R181Q	Neutral	0.403
SLC26A4	O43511-1.1	R181S	Neutral	0.285
SLC26A4	O43511-1.1	R181T	Neutral	0.467
SLC26A4	O43511-1.1	R181V	Pathogenic	0.808
SLC26A4	O43511-1.1	R181W	Pathogenic	0.909
SLC26A4	O43511-1.1	R181Y	Pathogenic	0.921
SLC26A4	O43511-1.1	D182A	Pathogenic	0.983
SLC26A4	O43511-1.1	D182C	Pathogenic	0.995
SLC26A4	O43511-1.1	D182E	Pathogenic	0.867
SLC26A4	O43511-1.1	D182F	Pathogenic	0.963
SLC26A4	O43511-1.1	D182G	Pathogenic	0.93
SLC26A4	O43511-1.1	D182H	Pathogenic	0.963
SLC26A4	O43511-1.1	D182I	Pathogenic	0.977
SLC26A4	O43511-1.1	D182K	Pathogenic	0.94
SLC26A4	O43511-1.1	D182L	Pathogenic	0.989
SLC26A4	O43511-1.1	D182M	Pathogenic	0.981
SLC26A4	O43511-1.1	D182N	Pathogenic	0.959
SLC26A4	O43511-1.1	D182P	Pathogenic	0.985
SLC26A4	O43511-1.1	D182Q	Pathogenic	0.947
SLC26A4	O43511-1.1	D182R	Pathogenic	0.946
SLC26A4	O43511-1.1	D182S	Pathogenic	0.954
SLC26A4	O43511-1.1	D182T	Pathogenic	0.987
SLC26A4	O43511-1.1	D182V	Pathogenic	0.992
SLC26A4	O43511-1.1	D182W	Pathogenic	0.925
SLC26A4	O43511-1.1	D182Y	Pathogenic	0.964
SLC26A4	O43511-1.1	T183A	Neutral	0.058
SLC26A4	O43511-1.1	T183C	Neutral	0.184
SLC26A4	O43511-1.1	T183D	Neutral	0.201
SLC26A4	O43511-1.1	T183E	Neutral	0.123
SLC26A4	O43511-1.1	T183F	Neutral	0.064
SLC26A4	O43511-1.1	T183G	Neutral	0.089
SLC26A4	O43511-1.1	T183H	Neutral	0.202
SLC26A4	O43511-1.1	T183I	Neutral	0.053
SLC26A4	O43511-1.1	T183K	Neutral	0.037
SLC26A4	O43511-1.1	T183L	Neutral	0.055
SLC26A4	O43511-1.1	T183M	Neutral	0.065
SLC26A4	O43511-1.1	T183N	Neutral	0.113
SLC26A4	O43511-1.1	T183P	Neutral	0.23
SLC26A4	O43511-1.1	T183Q	Neutral	0.116
SLC26A4	O43511-1.1	T183R	Neutral	0.021
SLC26A4	O43511-1.1	T183S	Neutral	0.035
SLC26A4	O43511-1.1	T183V	Neutral	0.075
SLC26A4	O43511-1.1	T183W	Neutral	0.016
SLC26A4	O43511-1.1	T183Y	Neutral	0.067
SLC26A4	O43511-1.1	A184C	Neutral	0.064
SLC26A4	O43511-1.1	A184D	Neutral	0.158
SLC26A4	O43511-1.1	A184E	Neutral	0.042
SLC26A4	O43511-1.1	A184F	Neutral	0.022
SLC26A4	O43511-1.1	A184G	Neutral	0.073
SLC26A4	O43511-1.1	A184H	Neutral	0.073
SLC26A4	O43511-1.1	A184I	Neutral	0.018
SLC26A4	O43511-1.1	A184K	Neutral	0.012
SLC26A4	O43511-1.1	A184L	Neutral	0.018
SLC26A4	O43511-1.1	A184M	Neutral	0.022
SLC26A4	O43511-1.1	A184N	Neutral	0.138
SLC26A4	O43511-1.1	A184P	Neutral	0.112
SLC26A4	O43511-1.1	A184Q	Neutral	0.039
SLC26A4	O43511-1.1	A184R	Neutral	0.006
SLC26A4	O43511-1.1	A184S	Neutral	0.065
SLC26A4	O43511-1.1	A184T	Neutral	0.059
SLC26A4	O43511-1.1	A184V	Neutral	0.026
SLC26A4	O43511-1.1	A184W	Neutral	0.01
SLC26A4	O43511-1.1	A184Y	Neutral	0.023
SLC26A4	O43511-1.1	R185A	Pathogenic	0.895
SLC26A4	O43511-1.1	R185C	Pathogenic	0.984
SLC26A4	O43511-1.1	R185D	Pathogenic	0.987
SLC26A4	O43511-1.1	R185E	Pathogenic	0.976
SLC26A4	O43511-1.1	R185F	Pathogenic	0.998
SLC26A4	O43511-1.1	R185G	Pathogenic	0.892
SLC26A4	O43511-1.1	R185H	Pathogenic	0.979
SLC26A4	O43511-1.1	R185I	Pathogenic	0.996
SLC26A4	O43511-1.1	R185K	Pathogenic	0.974
SLC26A4	O43511-1.1	R185L	Pathogenic	0.992
SLC26A4	O43511-1.1	R185M	Pathogenic	0.987
SLC26A4	O43511-1.1	R185N	Pathogenic	0.957
SLC26A4	O43511-1.1	R185P	Pathogenic	0.976
SLC26A4	O43511-1.1	R185Q	Pathogenic	0.956
SLC26A4	O43511-1.1	R185S	Pathogenic	0.928
SLC26A4	O43511-1.1	R185T	Pathogenic	0.966
SLC26A4	O43511-1.1	R185V	Pathogenic	0.993
SLC26A4	O43511-1.1	R185W	Pathogenic	0.997
SLC26A4	O43511-1.1	R185Y	Pathogenic	0.997
SLC26A4	O43511-1.1	V186A	Pathogenic	0.888
SLC26A4	O43511-1.1	V186C	Pathogenic	0.98
SLC26A4	O43511-1.1	V186D	Pathogenic	0.992
SLC26A4	O43511-1.1	V186E	Pathogenic	0.99
SLC26A4	O43511-1.1	V186F	Pathogenic	0.963
SLC26A4	O43511-1.1	V186G	Pathogenic	0.96
SLC26A4	O43511-1.1	V186H	Pathogenic	0.995
SLC26A4	O43511-1.1	V186I	Pathogenic	0.723
SLC26A4	O43511-1.1	V186K	Pathogenic	0.965
SLC26A4	O43511-1.1	V186L	Pathogenic	0.916
SLC26A4	O43511-1.1	V186M	Pathogenic	0.929
SLC26A4	O43511-1.1	V186N	Pathogenic	0.994
SLC26A4	O43511-1.1	V186P	Pathogenic	0.991
SLC26A4	O43511-1.1	V186Q	Pathogenic	0.99
SLC26A4	O43511-1.1	V186R	Pathogenic	0.969
SLC26A4	O43511-1.1	V186S	Pathogenic	0.973
SLC26A4	O43511-1.1	V186T	Pathogenic	0.962
SLC26A4	O43511-1.1	V186W	Pathogenic	0.961
SLC26A4	O43511-1.1	V186Y	Pathogenic	0.957
SLC26A4	O43511-1.1	L187A	Neutral	0.074
SLC26A4	O43511-1.1	L187C	Neutral	0.196
SLC26A4	O43511-1.1	L187D	Pathogenic	0.558
SLC26A4	O43511-1.1	L187E	Pathogenic	0.599
SLC26A4	O43511-1.1	L187F	Neutral	0.344
SLC26A4	O43511-1.1	L187G	Neutral	0.196
SLC26A4	O43511-1.1	L187H	Pathogenic	0.751
SLC26A4	O43511-1.1	L187I	Neutral	0.175
SLC26A4	O43511-1.1	L187K	Neutral	0.437
SLC26A4	O43511-1.1	L187M	Neutral	0.156
SLC26A4	O43511-1.1	L187N	Neutral	0.457
SLC26A4	O43511-1.1	L187P	Pathogenic	0.516
SLC26A4	O43511-1.1	L187Q	Pathogenic	0.522
SLC26A4	O43511-1.1	L187R	Neutral	0.3
SLC26A4	O43511-1.1	L187S	Neutral	0.156
SLC26A4	O43511-1.1	L187T	Neutral	0.202
SLC26A4	O43511-1.1	L187V	Neutral	0.135
SLC26A4	O43511-1.1	L187W	Neutral	0.334
SLC26A4	O43511-1.1	L187Y	Neutral	0.385
SLC26A4	O43511-1.1	I188A	Neutral	0.257
SLC26A4	O43511-1.1	I188C	Pathogenic	0.514
SLC26A4	O43511-1.1	I188D	Pathogenic	0.732
SLC26A4	O43511-1.1	I188E	Pathogenic	0.866
SLC26A4	O43511-1.1	I188F	Pathogenic	0.709
SLC26A4	O43511-1.1	I188G	Pathogenic	0.514
SLC26A4	O43511-1.1	I188H	Pathogenic	0.929
SLC26A4	O43511-1.1	I188K	Pathogenic	0.871
SLC26A4	O43511-1.1	I188L	Neutral	0.489
SLC26A4	O43511-1.1	I188M	Pathogenic	0.616
SLC26A4	O43511-1.1	I188N	Pathogenic	0.785
SLC26A4	O43511-1.1	I188P	Pathogenic	0.822
SLC26A4	O43511-1.1	I188Q	Pathogenic	0.905
SLC26A4	O43511-1.1	I188R	Pathogenic	0.789
SLC26A4	O43511-1.1	I188S	Neutral	0.444
SLC26A4	O43511-1.1	I188T	Pathogenic	0.523
SLC26A4	O43511-1.1	I188V	Neutral	0.144
SLC26A4	O43511-1.1	I188W	Pathogenic	0.825
SLC26A4	O43511-1.1	I188Y	Pathogenic	0.73
SLC26A4	O43511-1.1	A189C	Pathogenic	0.988
SLC26A4	O43511-1.1	A189D	Pathogenic	0.996
SLC26A4	O43511-1.1	A189E	Pathogenic	0.982
SLC26A4	O43511-1.1	A189F	Pathogenic	0.965
SLC26A4	O43511-1.1	A189G	Pathogenic	0.99
SLC26A4	O43511-1.1	A189H	Pathogenic	0.99
SLC26A4	O43511-1.1	A189I	Pathogenic	0.957
SLC26A4	O43511-1.1	A189K	Pathogenic	0.936
SLC26A4	O43511-1.1	A189L	Pathogenic	0.959
SLC26A4	O43511-1.1	A189M	Pathogenic	0.965
SLC26A4	O43511-1.1	A189N	Pathogenic	0.995
SLC26A4	O43511-1.1	A189P	Pathogenic	0.994
SLC26A4	O43511-1.1	A189Q	Pathogenic	0.981
SLC26A4	O43511-1.1	A189R	Pathogenic	0.891
SLC26A4	O43511-1.1	A189S	Pathogenic	0.989
SLC26A4	O43511-1.1	A189T	Pathogenic	0.987
SLC26A4	O43511-1.1	A189V	Pathogenic	0.971
SLC26A4	O43511-1.1	A189W	Pathogenic	0.929
SLC26A4	O43511-1.1	A189Y	Pathogenic	0.967
SLC26A4	O43511-1.1	S190A	Pathogenic	0.588
SLC26A4	O43511-1.1	S190C	Pathogenic	0.764
SLC26A4	O43511-1.1	S190D	Pathogenic	0.59
SLC26A4	O43511-1.1	S190E	Neutral	0.401
SLC26A4	O43511-1.1	S190F	Neutral	0.343
SLC26A4	O43511-1.1	S190G	Pathogenic	0.578
SLC26A4	O43511-1.1	S190H	Pathogenic	0.515
SLC26A4	O43511-1.1	S190I	Neutral	0.46
SLC26A4	O43511-1.1	S190K	Neutral	0.153
SLC26A4	O43511-1.1	S190L	Neutral	0.47
SLC26A4	O43511-1.1	S190M	Neutral	0.346
SLC26A4	O43511-1.1	S190N	Neutral	0.378
SLC26A4	O43511-1.1	S190P	Pathogenic	0.75
SLC26A4	O43511-1.1	S190Q	Neutral	0.386
SLC26A4	O43511-1.1	S190R	Neutral	0.167
SLC26A4	O43511-1.1	S190T	Neutral	0.436
SLC26A4	O43511-1.1	S190V	Pathogenic	0.716
SLC26A4	O43511-1.1	S190W	Neutral	0.199
SLC26A4	O43511-1.1	S190Y	Neutral	0.354
SLC26A4	O43511-1.1	A191C	Neutral	0.09
SLC26A4	O43511-1.1	A191D	Neutral	0.215
SLC26A4	O43511-1.1	A191E	Neutral	0.06
SLC26A4	O43511-1.1	A191F	Neutral	0.031
SLC26A4	O43511-1.1	A191G	Neutral	0.103
SLC26A4	O43511-1.1	A191H	Neutral	0.103
SLC26A4	O43511-1.1	A191I	Neutral	0.026
SLC26A4	O43511-1.1	A191K	Neutral	0.017
SLC26A4	O43511-1.1	A191L	Neutral	0.027
SLC26A4	O43511-1.1	A191M	Neutral	0.032
SLC26A4	O43511-1.1	A191N	Neutral	0.189
SLC26A4	O43511-1.1	A191P	Neutral	0.156
SLC26A4	O43511-1.1	A191Q	Neutral	0.056
SLC26A4	O43511-1.1	A191R	Neutral	0.009
SLC26A4	O43511-1.1	A191S	Neutral	0.092
SLC26A4	O43511-1.1	A191T	Neutral	0.084
SLC26A4	O43511-1.1	A191V	Neutral	0.037
SLC26A4	O43511-1.1	A191W	Neutral	0.015
SLC26A4	O43511-1.1	A191Y	Neutral	0.033
SLC26A4	O43511-1.1	L192A	Neutral	0.216
SLC26A4	O43511-1.1	L192C	Neutral	0.457
SLC26A4	O43511-1.1	L192D	Pathogenic	0.813
SLC26A4	O43511-1.1	L192E	Pathogenic	0.837
SLC26A4	O43511-1.1	L192F	Pathogenic	0.644
SLC26A4	O43511-1.1	L192G	Neutral	0.457
SLC26A4	O43511-1.1	L192H	Pathogenic	0.912
SLC26A4	O43511-1.1	L192I	Neutral	0.423
SLC26A4	O43511-1.1	L192K	Pathogenic	0.728
SLC26A4	O43511-1.1	L192M	Neutral	0.389
SLC26A4	O43511-1.1	L192N	Pathogenic	0.744
SLC26A4	O43511-1.1	L192P	Pathogenic	0.786
SLC26A4	O43511-1.1	L192Q	Pathogenic	0.79
SLC26A4	O43511-1.1	L192R	Pathogenic	0.597
SLC26A4	O43511-1.1	L192S	Neutral	0.389
SLC26A4	O43511-1.1	L192T	Neutral	0.466
SLC26A4	O43511-1.1	L192V	Neutral	0.35
SLC26A4	O43511-1.1	L192W	Pathogenic	0.633
SLC26A4	O43511-1.1	L192Y	Pathogenic	0.683
SLC26A4	O43511-1.1	T193A	Pathogenic	0.979
SLC26A4	O43511-1.1	T193C	Pathogenic	0.994
SLC26A4	O43511-1.1	T193D	Pathogenic	0.995
SLC26A4	O43511-1.1	T193E	Pathogenic	0.991
SLC26A4	O43511-1.1	T193F	Pathogenic	0.981
SLC26A4	O43511-1.1	T193G	Pathogenic	0.987
SLC26A4	O43511-1.1	T193H	Pathogenic	0.995
SLC26A4	O43511-1.1	T193I	Pathogenic	0.977
SLC26A4	O43511-1.1	T193K	Pathogenic	0.966
SLC26A4	O43511-1.1	T193L	Pathogenic	0.978
SLC26A4	O43511-1.1	T193M	Pathogenic	0.981
SLC26A4	O43511-1.1	T193N	Pathogenic	0.99
SLC26A4	O43511-1.1	T193P	Pathogenic	0.996
SLC26A4	O43511-1.1	T193Q	Pathogenic	0.99
SLC26A4	O43511-1.1	T193R	Pathogenic	0.94
SLC26A4	O43511-1.1	T193S	Pathogenic	0.965
SLC26A4	O43511-1.1	T193V	Pathogenic	0.984
SLC26A4	O43511-1.1	T193W	Pathogenic	0.924
SLC26A4	O43511-1.1	T193Y	Pathogenic	0.982
SLC26A4	O43511-1.1	L194A	Neutral	0.042
SLC26A4	O43511-1.1	L194C	Neutral	0.118
SLC26A4	O43511-1.1	L194D	Neutral	0.41
SLC26A4	O43511-1.1	L194E	Neutral	0.451
SLC26A4	O43511-1.1	L194F	Neutral	0.224
SLC26A4	O43511-1.1	L194G	Neutral	0.118
SLC26A4	O43511-1.1	L194H	Pathogenic	0.624
SLC26A4	O43511-1.1	L194I	Neutral	0.105
SLC26A4	O43511-1.1	L194K	Neutral	0.299
SLC26A4	O43511-1.1	L194M	Neutral	0.092
SLC26A4	O43511-1.1	L194N	Neutral	0.316
SLC26A4	O43511-1.1	L194P	Neutral	0.37
SLC26A4	O43511-1.1	L194Q	Neutral	0.375
SLC26A4	O43511-1.1	L194R	Neutral	0.191
SLC26A4	O43511-1.1	L194S	Neutral	0.092
SLC26A4	O43511-1.1	L194T	Neutral	0.122
SLC26A4	O43511-1.1	L194V	Neutral	0.079
SLC26A4	O43511-1.1	L194W	Neutral	0.216
SLC26A4	O43511-1.1	L194Y	Neutral	0.256
SLC26A4	O43511-1.1	L195A	Pathogenic	0.904
SLC26A4	O43511-1.1	L195C	Pathogenic	0.966
SLC26A4	O43511-1.1	L195D	Pathogenic	0.993
SLC26A4	O43511-1.1	L195E	Pathogenic	0.994
SLC26A4	O43511-1.1	L195F	Pathogenic	0.984
SLC26A4	O43511-1.1	L195G	Pathogenic	0.966
SLC26A4	O43511-1.1	L195H	Pathogenic	0.997
SLC26A4	O43511-1.1	L195I	Pathogenic	0.961
SLC26A4	O43511-1.1	L195K	Pathogenic	0.989
SLC26A4	O43511-1.1	L195M	Pathogenic	0.956
SLC26A4	O43511-1.1	L195N	Pathogenic	0.99
SLC26A4	O43511-1.1	L195P	Pathogenic	0.992
SLC26A4	O43511-1.1	L195Q	Pathogenic	0.992
SLC26A4	O43511-1.1	L195R	Pathogenic	0.981
SLC26A4	O43511-1.1	L195S	Pathogenic	0.956
SLC26A4	O43511-1.1	L195T	Pathogenic	0.967
SLC26A4	O43511-1.1	L195V	Pathogenic	0.948
SLC26A4	O43511-1.1	L195W	Pathogenic	0.983
SLC26A4	O43511-1.1	L195Y	Pathogenic	0.987
SLC26A4	O43511-1.1	V196A	Neutral	0.156
SLC26A4	O43511-1.1	V196C	Pathogenic	0.532
SLC26A4	O43511-1.1	V196D	Pathogenic	0.745
SLC26A4	O43511-1.1	V196E	Pathogenic	0.706
SLC26A4	O43511-1.1	V196F	Neutral	0.378
SLC26A4	O43511-1.1	V196G	Neutral	0.361
SLC26A4	O43511-1.1	V196H	Pathogenic	0.812
SLC26A4	O43511-1.1	V196I	Neutral	0.057
SLC26A4	O43511-1.1	V196K	Neutral	0.394
SLC26A4	O43511-1.1	V196L	Neutral	0.204
SLC26A4	O43511-1.1	V196M	Neutral	0.234
SLC26A4	O43511-1.1	V196N	Pathogenic	0.796
SLC26A4	O43511-1.1	V196P	Pathogenic	0.712
SLC26A4	O43511-1.1	V196Q	Pathogenic	0.693
SLC26A4	O43511-1.1	V196R	Neutral	0.419
SLC26A4	O43511-1.1	V196S	Neutral	0.461
SLC26A4	O43511-1.1	V196T	Neutral	0.37
SLC26A4	O43511-1.1	V196W	Neutral	0.367
SLC26A4	O43511-1.1	V196Y	Neutral	0.343
SLC26A4	O43511-1.1	G197A	Pathogenic	0.993
SLC26A4	O43511-1.1	G197C	Pathogenic	0.997
SLC26A4	O43511-1.1	G197D	Pathogenic	0.988
SLC26A4	O43511-1.1	G197E	Pathogenic	0.987
SLC26A4	O43511-1.1	G197F	Pathogenic	0.968
SLC26A4	O43511-1.1	G197H	Pathogenic	0.984
SLC26A4	O43511-1.1	G197I	Pathogenic	0.99
SLC26A4	O43511-1.1	G197K	Pathogenic	0.953
SLC26A4	O43511-1.1	G197L	Pathogenic	0.99
SLC26A4	O43511-1.1	G197M	Pathogenic	0.984
SLC26A4	O43511-1.1	G197N	Pathogenic	0.971
SLC26A4	O43511-1.1	G197P	Pathogenic	0.994
SLC26A4	O43511-1.1	G197Q	Pathogenic	0.986
SLC26A4	O43511-1.1	G197R	Pathogenic	0.918
SLC26A4	O43511-1.1	G197S	Pathogenic	0.992
SLC26A4	O43511-1.1	G197T	Pathogenic	0.994
SLC26A4	O43511-1.1	G197V	Pathogenic	0.993
SLC26A4	O43511-1.1	G197W	Pathogenic	0.778
SLC26A4	O43511-1.1	G197Y	Pathogenic	0.969
SLC26A4	O43511-1.1	I198A	Pathogenic	0.733
SLC26A4	O43511-1.1	I198C	Pathogenic	0.893
SLC26A4	O43511-1.1	I198D	Pathogenic	0.956
SLC26A4	O43511-1.1	I198E	Pathogenic	0.981
SLC26A4	O43511-1.1	I198F	Pathogenic	0.951
SLC26A4	O43511-1.1	I198G	Pathogenic	0.893
SLC26A4	O43511-1.1	I198H	Pathogenic	0.99
SLC26A4	O43511-1.1	I198K	Pathogenic	0.982
SLC26A4	O43511-1.1	I198L	Pathogenic	0.883
SLC26A4	O43511-1.1	I198M	Pathogenic	0.927
SLC26A4	O43511-1.1	I198N	Pathogenic	0.966
SLC26A4	O43511-1.1	I198P	Pathogenic	0.973
SLC26A4	O43511-1.1	I198Q	Pathogenic	0.987
SLC26A4	O43511-1.1	I198R	Pathogenic	0.967
SLC26A4	O43511-1.1	I198S	Pathogenic	0.863
SLC26A4	O43511-1.1	I198T	Pathogenic	0.897
SLC26A4	O43511-1.1	I198V	Pathogenic	0.57
SLC26A4	O43511-1.1	I198W	Pathogenic	0.974
SLC26A4	O43511-1.1	I198Y	Pathogenic	0.955
SLC26A4	O43511-1.1	I199A	Neutral	0.261
SLC26A4	O43511-1.1	I199C	Pathogenic	0.519
SLC26A4	O43511-1.1	I199D	Pathogenic	0.736
SLC26A4	O43511-1.1	I199E	Pathogenic	0.868
SLC26A4	O43511-1.1	I199F	Pathogenic	0.713
SLC26A4	O43511-1.1	I199G	Pathogenic	0.519
SLC26A4	O43511-1.1	I199H	Pathogenic	0.93
SLC26A4	O43511-1.1	I199K	Pathogenic	0.873
SLC26A4	O43511-1.1	I199L	Neutral	0.494
SLC26A4	O43511-1.1	I199M	Pathogenic	0.621
SLC26A4	O43511-1.1	I199N	Pathogenic	0.788
SLC26A4	O43511-1.1	I199P	Pathogenic	0.825
SLC26A4	O43511-1.1	I199Q	Pathogenic	0.907
SLC26A4	O43511-1.1	I199R	Pathogenic	0.792
SLC26A4	O43511-1.1	I199S	Neutral	0.449
SLC26A4	O43511-1.1	I199T	Pathogenic	0.529
SLC26A4	O43511-1.1	I199V	Neutral	0.146
SLC26A4	O43511-1.1	I199W	Pathogenic	0.828
SLC26A4	O43511-1.1	I199Y	Pathogenic	0.734
SLC26A4	O43511-1.1	Q200A	Pathogenic	0.996
SLC26A4	O43511-1.1	Q200C	Pathogenic	0.999
SLC26A4	O43511-1.1	Q200D	Pathogenic	0.997
SLC26A4	O43511-1.1	Q200E	Pathogenic	0.995
SLC26A4	O43511-1.1	Q200F	Pathogenic	0.999
SLC26A4	O43511-1.1	Q200G	Pathogenic	0.996
SLC26A4	O43511-1.1	Q200H	Pathogenic	0.999
SLC26A4	O43511-1.1	Q200I	Pathogenic	1.0
SLC26A4	O43511-1.1	Q200K	Pathogenic	0.994
SLC26A4	O43511-1.1	Q200L	Pathogenic	0.999
SLC26A4	O43511-1.1	Q200M	Pathogenic	0.998
SLC26A4	O43511-1.1	Q200N	Pathogenic	0.998
SLC26A4	O43511-1.1	Q200P	Pathogenic	0.998
SLC26A4	O43511-1.1	Q200R	Pathogenic	0.989
SLC26A4	O43511-1.1	Q200S	Pathogenic	0.994
SLC26A4	O43511-1.1	Q200T	Pathogenic	0.999
SLC26A4	O43511-1.1	Q200V	Pathogenic	0.999
SLC26A4	O43511-1.1	Q200W	Pathogenic	0.995
SLC26A4	O43511-1.1	Q200Y	Pathogenic	0.998
SLC26A4	O43511-1.1	L201A	Pathogenic	0.813
SLC26A4	O43511-1.1	L201C	Pathogenic	0.93
SLC26A4	O43511-1.1	L201D	Pathogenic	0.986
SLC26A4	O43511-1.1	L201E	Pathogenic	0.988
SLC26A4	O43511-1.1	L201F	Pathogenic	0.966
SLC26A4	O43511-1.1	L201G	Pathogenic	0.93
SLC26A4	O43511-1.1	L201H	Pathogenic	0.994
SLC26A4	O43511-1.1	L201I	Pathogenic	0.92
SLC26A4	O43511-1.1	L201K	Pathogenic	0.977
SLC26A4	O43511-1.1	L201M	Pathogenic	0.909
SLC26A4	O43511-1.1	L201N	Pathogenic	0.979
SLC26A4	O43511-1.1	L201P	Pathogenic	0.983
SLC26A4	O43511-1.1	L201Q	Pathogenic	0.983
SLC26A4	O43511-1.1	L201R	Pathogenic	0.959
SLC26A4	O43511-1.1	L201S	Pathogenic	0.909
SLC26A4	O43511-1.1	L201T	Pathogenic	0.932
SLC26A4	O43511-1.1	L201V	Pathogenic	0.895
SLC26A4	O43511-1.1	L201W	Pathogenic	0.965
SLC26A4	O43511-1.1	L201Y	Pathogenic	0.971
SLC26A4	O43511-1.1	I202A	Neutral	0.016
SLC26A4	O43511-1.1	I202C	Neutral	0.048
SLC26A4	O43511-1.1	I202D	Neutral	0.114
SLC26A4	O43511-1.1	I202E	Neutral	0.235
SLC26A4	O43511-1.1	I202F	Neutral	0.103
SLC26A4	O43511-1.1	I202G	Neutral	0.048
SLC26A4	O43511-1.1	I202H	Neutral	0.382
SLC26A4	O43511-1.1	I202K	Neutral	0.243
SLC26A4	O43511-1.1	I202L	Neutral	0.043
SLC26A4	O43511-1.1	I202M	Neutral	0.071
SLC26A4	O43511-1.1	I202N	Neutral	0.147
SLC26A4	O43511-1.1	I202P	Neutral	0.18
SLC26A4	O43511-1.1	I202Q	Neutral	0.311
SLC26A4	O43511-1.1	I202R	Neutral	0.151
SLC26A4	O43511-1.1	I202S	Neutral	0.037
SLC26A4	O43511-1.1	I202T	Neutral	0.049
SLC26A4	O43511-1.1	I202V	Neutral	0.008
SLC26A4	O43511-1.1	I202W	Neutral	0.183
SLC26A4	O43511-1.1	I202Y	Neutral	0.114
SLC26A4	O43511-1.1	F203A	Neutral	0.327
SLC26A4	O43511-1.1	F203C	Pathogenic	0.597
SLC26A4	O43511-1.1	F203D	Pathogenic	0.655
SLC26A4	O43511-1.1	F203E	Pathogenic	0.818
SLC26A4	O43511-1.1	F203G	Neutral	0.268
SLC26A4	O43511-1.1	F203H	Pathogenic	0.693
SLC26A4	O43511-1.1	F203I	Pathogenic	0.735
SLC26A4	O43511-1.1	F203K	Pathogenic	0.927
SLC26A4	O43511-1.1	F203L	Pathogenic	0.729
SLC26A4	O43511-1.1	F203M	Pathogenic	0.692
SLC26A4	O43511-1.1	F203N	Pathogenic	0.718
SLC26A4	O43511-1.1	F203P	Pathogenic	0.866
SLC26A4	O43511-1.1	F203Q	Pathogenic	0.869
SLC26A4	O43511-1.1	F203R	Pathogenic	0.875
SLC26A4	O43511-1.1	F203S	Neutral	0.358
SLC26A4	O43511-1.1	F203T	Pathogenic	0.606
SLC26A4	O43511-1.1	F203V	Pathogenic	0.656
SLC26A4	O43511-1.1	F203W	Neutral	0.35
SLC26A4	O43511-1.1	F203Y	Neutral	0.238
SLC26A4	O43511-1.1	G204A	Pathogenic	0.993
SLC26A4	O43511-1.1	G204C	Pathogenic	0.997
SLC26A4	O43511-1.1	G204D	Pathogenic	0.988
SLC26A4	O43511-1.1	G204E	Pathogenic	0.987
SLC26A4	O43511-1.1	G204F	Pathogenic	0.968
SLC26A4	O43511-1.1	G204H	Pathogenic	0.984
SLC26A4	O43511-1.1	G204I	Pathogenic	0.99
SLC26A4	O43511-1.1	G204K	Pathogenic	0.953
SLC26A4	O43511-1.1	G204L	Pathogenic	0.99
SLC26A4	O43511-1.1	G204M	Pathogenic	0.984
SLC26A4	O43511-1.1	G204N	Pathogenic	0.971
SLC26A4	O43511-1.1	G204P	Pathogenic	0.994
SLC26A4	O43511-1.1	G204Q	Pathogenic	0.986
SLC26A4	O43511-1.1	G204R	Pathogenic	0.918
SLC26A4	O43511-1.1	G204S	Pathogenic	0.992
SLC26A4	O43511-1.1	G204T	Pathogenic	0.994
SLC26A4	O43511-1.1	G204V	Pathogenic	0.993
SLC26A4	O43511-1.1	G204W	Pathogenic	0.778
SLC26A4	O43511-1.1	G204Y	Pathogenic	0.969
SLC26A4	O43511-1.1	G205A	Neutral	0.076
SLC26A4	O43511-1.1	G205C	Neutral	0.18
SLC26A4	O43511-1.1	G205D	Neutral	0.045
SLC26A4	O43511-1.1	G205E	Neutral	0.042
SLC26A4	O43511-1.1	G205F	Neutral	0.017
SLC26A4	O43511-1.1	G205H	Neutral	0.035
SLC26A4	O43511-1.1	G205I	Neutral	0.055
SLC26A4	O43511-1.1	G205K	Neutral	0.012
SLC26A4	O43511-1.1	G205L	Neutral	0.057
SLC26A4	O43511-1.1	G205M	Neutral	0.035
SLC26A4	O43511-1.1	G205N	Neutral	0.02
SLC26A4	O43511-1.1	G205P	Neutral	0.092
SLC26A4	O43511-1.1	G205Q	Neutral	0.04
SLC26A4	O43511-1.1	G205R	Neutral	0.007
SLC26A4	O43511-1.1	G205S	Neutral	0.065
SLC26A4	O43511-1.1	G205T	Neutral	0.095
SLC26A4	O43511-1.1	G205V	Neutral	0.078
SLC26A4	O43511-1.1	G205W	Neutral	0.002
SLC26A4	O43511-1.1	G205Y	Neutral	0.018
SLC26A4	O43511-1.1	L206A	Pathogenic	0.817
SLC26A4	O43511-1.1	L206C	Pathogenic	0.932
SLC26A4	O43511-1.1	L206D	Pathogenic	0.986
SLC26A4	O43511-1.1	L206E	Pathogenic	0.988
SLC26A4	O43511-1.1	L206F	Pathogenic	0.967
SLC26A4	O43511-1.1	L206G	Pathogenic	0.932
SLC26A4	O43511-1.1	L206H	Pathogenic	0.994
SLC26A4	O43511-1.1	L206I	Pathogenic	0.922
SLC26A4	O43511-1.1	L206K	Pathogenic	0.977
SLC26A4	O43511-1.1	L206M	Pathogenic	0.911
SLC26A4	O43511-1.1	L206N	Pathogenic	0.979
SLC26A4	O43511-1.1	L206P	Pathogenic	0.983
SLC26A4	O43511-1.1	L206Q	Pathogenic	0.984
SLC26A4	O43511-1.1	L206R	Pathogenic	0.96
SLC26A4	O43511-1.1	L206S	Pathogenic	0.911
SLC26A4	O43511-1.1	L206T	Pathogenic	0.934
SLC26A4	O43511-1.1	L206V	Pathogenic	0.897
SLC26A4	O43511-1.1	L206W	Pathogenic	0.965
SLC26A4	O43511-1.1	L206Y	Pathogenic	0.972
SLC26A4	O43511-1.1	Q207A	Pathogenic	0.968
SLC26A4	O43511-1.1	Q207C	Pathogenic	0.996
SLC26A4	O43511-1.1	Q207D	Pathogenic	0.978
SLC26A4	O43511-1.1	Q207E	Pathogenic	0.963
SLC26A4	O43511-1.1	Q207F	Pathogenic	0.996
SLC26A4	O43511-1.1	Q207G	Pathogenic	0.967
SLC26A4	O43511-1.1	Q207H	Pathogenic	0.991
SLC26A4	O43511-1.1	Q207I	Pathogenic	0.997
SLC26A4	O43511-1.1	Q207K	Pathogenic	0.957
SLC26A4	O43511-1.1	Q207L	Pathogenic	0.995
SLC26A4	O43511-1.1	Q207M	Pathogenic	0.983
SLC26A4	O43511-1.1	Q207N	Pathogenic	0.983
SLC26A4	O43511-1.1	Q207P	Pathogenic	0.987
SLC26A4	O43511-1.1	Q207R	Pathogenic	0.925
SLC26A4	O43511-1.1	Q207S	Pathogenic	0.958
SLC26A4	O43511-1.1	Q207T	Pathogenic	0.99
SLC26A4	O43511-1.1	Q207V	Pathogenic	0.996
SLC26A4	O43511-1.1	Q207W	Pathogenic	0.964
SLC26A4	O43511-1.1	Q207Y	Pathogenic	0.983
SLC26A4	O43511-1.1	I208A	Neutral	0.149
SLC26A4	O43511-1.1	I208C	Neutral	0.349
SLC26A4	O43511-1.1	I208D	Pathogenic	0.58
SLC26A4	O43511-1.1	I208E	Pathogenic	0.766
SLC26A4	O43511-1.1	I208F	Pathogenic	0.552
SLC26A4	O43511-1.1	I208G	Neutral	0.349
SLC26A4	O43511-1.1	I208H	Pathogenic	0.869
SLC26A4	O43511-1.1	I208K	Pathogenic	0.774
SLC26A4	O43511-1.1	I208L	Neutral	0.327
SLC26A4	O43511-1.1	I208M	Neutral	0.449
SLC26A4	O43511-1.1	I208N	Pathogenic	0.649
SLC26A4	O43511-1.1	I208P	Pathogenic	0.701
SLC26A4	O43511-1.1	I208Q	Pathogenic	0.828
SLC26A4	O43511-1.1	I208R	Pathogenic	0.655
SLC26A4	O43511-1.1	I208S	Neutral	0.288
SLC26A4	O43511-1.1	I208T	Neutral	0.358
SLC26A4	O43511-1.1	I208V	Neutral	0.078
SLC26A4	O43511-1.1	I208W	Pathogenic	0.705
SLC26A4	O43511-1.1	I208Y	Pathogenic	0.579
SLC26A4	O43511-1.1	G209A	Pathogenic	0.993
SLC26A4	O43511-1.1	G209C	Pathogenic	0.997
SLC26A4	O43511-1.1	G209D	Pathogenic	0.988
SLC26A4	O43511-1.1	G209E	Pathogenic	0.987
SLC26A4	O43511-1.1	G209F	Pathogenic	0.968
SLC26A4	O43511-1.1	G209H	Pathogenic	0.984
SLC26A4	O43511-1.1	G209I	Pathogenic	0.99
SLC26A4	O43511-1.1	G209K	Pathogenic	0.953
SLC26A4	O43511-1.1	G209L	Pathogenic	0.99
SLC26A4	O43511-1.1	G209M	Pathogenic	0.984
SLC26A4	O43511-1.1	G209N	Pathogenic	0.971
SLC26A4	O43511-1.1	G209P	Pathogenic	0.994
SLC26A4	O43511-1.1	G209Q	Pathogenic	0.986
SLC26A4	O43511-1.1	G209R	Pathogenic	0.918
SLC26A4	O43511-1.1	G209S	Pathogenic	0.992
SLC26A4	O43511-1.1	G209T	Pathogenic	0.994
SLC26A4	O43511-1.1	G209V	Pathogenic	0.993
SLC26A4	O43511-1.1	G209W	Pathogenic	0.778
SLC26A4	O43511-1.1	G209Y	Pathogenic	0.969
SLC26A4	O43511-1.1	F210A	Pathogenic	0.978
SLC26A4	O43511-1.1	F210C	Pathogenic	0.993
SLC26A4	O43511-1.1	F210D	Pathogenic	0.994
SLC26A4	O43511-1.1	F210E	Pathogenic	0.998
SLC26A4	O43511-1.1	F210G	Pathogenic	0.971
SLC26A4	O43511-1.1	F210H	Pathogenic	0.995
SLC26A4	O43511-1.1	F210I	Pathogenic	0.996
SLC26A4	O43511-1.1	F210K	Pathogenic	0.999
SLC26A4	O43511-1.1	F210L	Pathogenic	0.996
SLC26A4	O43511-1.1	F210M	Pathogenic	0.995
SLC26A4	O43511-1.1	F210N	Pathogenic	0.996
SLC26A4	O43511-1.1	F210P	Pathogenic	0.998
SLC26A4	O43511-1.1	F210Q	Pathogenic	0.998
SLC26A4	O43511-1.1	F210R	Pathogenic	0.998
SLC26A4	O43511-1.1	F210S	Pathogenic	0.981
SLC26A4	O43511-1.1	F210T	Pathogenic	0.993
SLC26A4	O43511-1.1	F210V	Pathogenic	0.994
SLC26A4	O43511-1.1	F210W	Pathogenic	0.98
SLC26A4	O43511-1.1	F210Y	Pathogenic	0.966
SLC26A4	O43511-1.1	I211A	Neutral	0.402
SLC26A4	O43511-1.1	I211C	Pathogenic	0.672
SLC26A4	O43511-1.1	I211D	Pathogenic	0.841
SLC26A4	O43511-1.1	I211E	Pathogenic	0.926
SLC26A4	O43511-1.1	I211F	Pathogenic	0.825
SLC26A4	O43511-1.1	I211G	Pathogenic	0.672
SLC26A4	O43511-1.1	I211H	Pathogenic	0.962
SLC26A4	O43511-1.1	I211K	Pathogenic	0.929
SLC26A4	O43511-1.1	I211L	Pathogenic	0.65
SLC26A4	O43511-1.1	I211M	Pathogenic	0.757
SLC26A4	O43511-1.1	I211N	Pathogenic	0.876
SLC26A4	O43511-1.1	I211P	Pathogenic	0.9
SLC26A4	O43511-1.1	I211Q	Pathogenic	0.949
SLC26A4	O43511-1.1	I211R	Pathogenic	0.879
SLC26A4	O43511-1.1	I211S	Pathogenic	0.608
SLC26A4	O43511-1.1	I211T	Pathogenic	0.68
SLC26A4	O43511-1.1	I211V	Neutral	0.245
SLC26A4	O43511-1.1	I211W	Pathogenic	0.901
SLC26A4	O43511-1.1	I211Y	Pathogenic	0.84
SLC26A4	O43511-1.1	V212A	Pathogenic	0.862
SLC26A4	O43511-1.1	V212C	Pathogenic	0.975
SLC26A4	O43511-1.1	V212D	Pathogenic	0.99
SLC26A4	O43511-1.1	V212E	Pathogenic	0.988
SLC26A4	O43511-1.1	V212F	Pathogenic	0.953
SLC26A4	O43511-1.1	V212G	Pathogenic	0.95
SLC26A4	O43511-1.1	V212H	Pathogenic	0.993
SLC26A4	O43511-1.1	V212I	Pathogenic	0.673
SLC26A4	O43511-1.1	V212K	Pathogenic	0.956
SLC26A4	O43511-1.1	V212L	Pathogenic	0.896
SLC26A4	O43511-1.1	V212M	Pathogenic	0.912
SLC26A4	O43511-1.1	V212N	Pathogenic	0.992
SLC26A4	O43511-1.1	V212P	Pathogenic	0.988
SLC26A4	O43511-1.1	V212Q	Pathogenic	0.987
SLC26A4	O43511-1.1	V212R	Pathogenic	0.961
SLC26A4	O43511-1.1	V212S	Pathogenic	0.967
SLC26A4	O43511-1.1	V212T	Pathogenic	0.952
SLC26A4	O43511-1.1	V212W	Pathogenic	0.951
SLC26A4	O43511-1.1	V212Y	Pathogenic	0.946
SLC26A4	O43511-1.1	R213A	Neutral	0.39
SLC26A4	O43511-1.1	R213C	Pathogenic	0.824
SLC26A4	O43511-1.1	R213D	Pathogenic	0.852
SLC26A4	O43511-1.1	R213E	Pathogenic	0.753
SLC26A4	O43511-1.1	R213F	Pathogenic	0.969
SLC26A4	O43511-1.1	R213G	Neutral	0.38
SLC26A4	O43511-1.1	R213H	Pathogenic	0.773
SLC26A4	O43511-1.1	R213I	Pathogenic	0.95
SLC26A4	O43511-1.1	R213K	Pathogenic	0.737
SLC26A4	O43511-1.1	R213L	Pathogenic	0.908
SLC26A4	O43511-1.1	R213M	Pathogenic	0.854
SLC26A4	O43511-1.1	R213N	Pathogenic	0.626
SLC26A4	O43511-1.1	R213P	Pathogenic	0.756
SLC26A4	O43511-1.1	R213Q	Pathogenic	0.618
SLC26A4	O43511-1.1	R213S	Neutral	0.489
SLC26A4	O43511-1.1	R213T	Pathogenic	0.678
SLC26A4	O43511-1.1	R213V	Pathogenic	0.91
SLC26A4	O43511-1.1	R213W	Pathogenic	0.96
SLC26A4	O43511-1.1	R213Y	Pathogenic	0.966
SLC26A4	O43511-1.1	Y214A	Pathogenic	0.996
SLC26A4	O43511-1.1	Y214C	Pathogenic	0.999
SLC26A4	O43511-1.1	Y214D	Pathogenic	0.999
SLC26A4	O43511-1.1	Y214E	Pathogenic	0.999
SLC26A4	O43511-1.1	Y214F	Pathogenic	0.994
SLC26A4	O43511-1.1	Y214G	Pathogenic	0.995
SLC26A4	O43511-1.1	Y214H	Pathogenic	0.993
SLC26A4	O43511-1.1	Y214I	Pathogenic	0.999
SLC26A4	O43511-1.1	Y214K	Pathogenic	1.0
SLC26A4	O43511-1.1	Y214L	Pathogenic	0.999
SLC26A4	O43511-1.1	Y214M	Pathogenic	0.999
SLC26A4	O43511-1.1	Y214N	Pathogenic	0.999
SLC26A4	O43511-1.1	Y214P	Pathogenic	0.999
SLC26A4	O43511-1.1	Y214Q	Pathogenic	0.999
SLC26A4	O43511-1.1	Y214R	Pathogenic	1.0
SLC26A4	O43511-1.1	Y214S	Pathogenic	0.997
SLC26A4	O43511-1.1	Y214T	Pathogenic	0.999
SLC26A4	O43511-1.1	Y214V	Pathogenic	0.999
SLC26A4	O43511-1.1	Y214W	Pathogenic	0.992
SLC26A4	O43511-1.1	L215A	Pathogenic	0.939
SLC26A4	O43511-1.1	L215C	Pathogenic	0.979
SLC26A4	O43511-1.1	L215D	Pathogenic	0.996
SLC26A4	O43511-1.1	L215E	Pathogenic	0.997
SLC26A4	O43511-1.1	L215F	Pathogenic	0.99
SLC26A4	O43511-1.1	L215G	Pathogenic	0.979
SLC26A4	O43511-1.1	L215H	Pathogenic	0.998
SLC26A4	O43511-1.1	L215I	Pathogenic	0.976
SLC26A4	O43511-1.1	L215K	Pathogenic	0.993
SLC26A4	O43511-1.1	L215M	Pathogenic	0.972
SLC26A4	O43511-1.1	L215N	Pathogenic	0.994
SLC26A4	O43511-1.1	L215P	Pathogenic	0.995
SLC26A4	O43511-1.1	L215Q	Pathogenic	0.995
SLC26A4	O43511-1.1	L215R	Pathogenic	0.988
SLC26A4	O43511-1.1	L215S	Pathogenic	0.972
SLC26A4	O43511-1.1	L215T	Pathogenic	0.98
SLC26A4	O43511-1.1	L215V	Pathogenic	0.968
SLC26A4	O43511-1.1	L215W	Pathogenic	0.99
SLC26A4	O43511-1.1	L215Y	Pathogenic	0.992
SLC26A4	O43511-1.1	A216C	Pathogenic	0.668
SLC26A4	O43511-1.1	A216D	Pathogenic	0.847
SLC26A4	O43511-1.1	A216E	Pathogenic	0.563
SLC26A4	O43511-1.1	A216F	Neutral	0.395
SLC26A4	O43511-1.1	A216G	Pathogenic	0.699
SLC26A4	O43511-1.1	A216H	Pathogenic	0.699
SLC26A4	O43511-1.1	A216I	Neutral	0.346
SLC26A4	O43511-1.1	A216K	Neutral	0.258
SLC26A4	O43511-1.1	A216L	Neutral	0.355
SLC26A4	O43511-1.1	A216M	Neutral	0.398
SLC26A4	O43511-1.1	A216N	Pathogenic	0.825
SLC26A4	O43511-1.1	A216P	Pathogenic	0.789
SLC26A4	O43511-1.1	A216Q	Pathogenic	0.547
SLC26A4	O43511-1.1	A216R	Neutral	0.161
SLC26A4	O43511-1.1	A216S	Pathogenic	0.672
SLC26A4	O43511-1.1	A216T	Pathogenic	0.651
SLC26A4	O43511-1.1	A216V	Neutral	0.438
SLC26A4	O43511-1.1	A216W	Neutral	0.236
SLC26A4	O43511-1.1	A216Y	Neutral	0.406
SLC26A4	O43511-1.1	D217A	Pathogenic	0.931
SLC26A4	O43511-1.1	D217C	Pathogenic	0.98
SLC26A4	O43511-1.1	D217E	Pathogenic	0.61
SLC26A4	O43511-1.1	D217F	Pathogenic	0.862
SLC26A4	O43511-1.1	D217G	Pathogenic	0.763
SLC26A4	O43511-1.1	D217H	Pathogenic	0.863
SLC26A4	O43511-1.1	D217I	Pathogenic	0.91
SLC26A4	O43511-1.1	D217K	Pathogenic	0.792
SLC26A4	O43511-1.1	D217L	Pathogenic	0.955
SLC26A4	O43511-1.1	D217M	Pathogenic	0.927
SLC26A4	O43511-1.1	D217N	Pathogenic	0.848
SLC26A4	O43511-1.1	D217P	Pathogenic	0.942
SLC26A4	O43511-1.1	D217Q	Pathogenic	0.811
SLC26A4	O43511-1.1	D217R	Pathogenic	0.808
SLC26A4	O43511-1.1	D217S	Pathogenic	0.834
SLC26A4	O43511-1.1	D217T	Pathogenic	0.949
SLC26A4	O43511-1.1	D217V	Pathogenic	0.968
SLC26A4	O43511-1.1	D217W	Pathogenic	0.747
SLC26A4	O43511-1.1	D217Y	Pathogenic	0.867
SLC26A4	O43511-1.1	P218A	Pathogenic	0.924
SLC26A4	O43511-1.1	P218C	Pathogenic	0.992
SLC26A4	O43511-1.1	P218D	Pathogenic	0.956
SLC26A4	O43511-1.1	P218E	Pathogenic	0.91
SLC26A4	O43511-1.1	P218F	Pathogenic	0.966
SLC26A4	O43511-1.1	P218G	Pathogenic	0.902
SLC26A4	O43511-1.1	P218H	Pathogenic	0.948
SLC26A4	O43511-1.1	P218I	Pathogenic	0.958
SLC26A4	O43511-1.1	P218K	Pathogenic	0.731
SLC26A4	O43511-1.1	P218L	Pathogenic	0.96
SLC26A4	O43511-1.1	P218M	Pathogenic	0.934
SLC26A4	O43511-1.1	P218N	Pathogenic	0.974
SLC26A4	O43511-1.1	P218Q	Pathogenic	0.904
SLC26A4	O43511-1.1	P218R	Pathogenic	0.752
SLC26A4	O43511-1.1	P218S	Pathogenic	0.933
SLC26A4	O43511-1.1	P218T	Pathogenic	0.967
SLC26A4	O43511-1.1	P218V	Pathogenic	0.971
SLC26A4	O43511-1.1	P218W	Pathogenic	0.87
SLC26A4	O43511-1.1	P218Y	Pathogenic	0.936
SLC26A4	O43511-1.1	L219A	Pathogenic	0.927
SLC26A4	O43511-1.1	L219C	Pathogenic	0.975
SLC26A4	O43511-1.1	L219D	Pathogenic	0.995
SLC26A4	O43511-1.1	L219E	Pathogenic	0.996
SLC26A4	O43511-1.1	L219F	Pathogenic	0.988
SLC26A4	O43511-1.1	L219G	Pathogenic	0.975
SLC26A4	O43511-1.1	L219H	Pathogenic	0.998
SLC26A4	O43511-1.1	L219I	Pathogenic	0.971
SLC26A4	O43511-1.1	L219K	Pathogenic	0.992
SLC26A4	O43511-1.1	L219M	Pathogenic	0.967
SLC26A4	O43511-1.1	L219N	Pathogenic	0.993
SLC26A4	O43511-1.1	L219P	Pathogenic	0.994
SLC26A4	O43511-1.1	L219Q	Pathogenic	0.994
SLC26A4	O43511-1.1	L219R	Pathogenic	0.986
SLC26A4	O43511-1.1	L219S	Pathogenic	0.967
SLC26A4	O43511-1.1	L219T	Pathogenic	0.976
SLC26A4	O43511-1.1	L219V	Pathogenic	0.961
SLC26A4	O43511-1.1	L219W	Pathogenic	0.988
SLC26A4	O43511-1.1	L219Y	Pathogenic	0.99
SLC26A4	O43511-1.1	V220A	Neutral	0.49
SLC26A4	O43511-1.1	V220C	Pathogenic	0.855
SLC26A4	O43511-1.1	V220D	Pathogenic	0.938
SLC26A4	O43511-1.1	V220E	Pathogenic	0.926
SLC26A4	O43511-1.1	V220F	Pathogenic	0.759
SLC26A4	O43511-1.1	V220G	Pathogenic	0.746
SLC26A4	O43511-1.1	V220H	Pathogenic	0.957
SLC26A4	O43511-1.1	V220I	Neutral	0.24
SLC26A4	O43511-1.1	V220K	Pathogenic	0.771
SLC26A4	O43511-1.1	V220L	Pathogenic	0.571
SLC26A4	O43511-1.1	V220M	Pathogenic	0.614
SLC26A4	O43511-1.1	V220N	Pathogenic	0.953
SLC26A4	O43511-1.1	V220P	Pathogenic	0.928
SLC26A4	O43511-1.1	V220Q	Pathogenic	0.921
SLC26A4	O43511-1.1	V220R	Pathogenic	0.789
SLC26A4	O43511-1.1	V220S	Pathogenic	0.817
SLC26A4	O43511-1.1	V220T	Pathogenic	0.753
SLC26A4	O43511-1.1	V220W	Pathogenic	0.751
SLC26A4	O43511-1.1	V220Y	Pathogenic	0.731
SLC26A4	O43511-1.1	G221A	Pathogenic	0.687
SLC26A4	O43511-1.1	G221C	Pathogenic	0.853
SLC26A4	O43511-1.1	G221D	Pathogenic	0.555
SLC26A4	O43511-1.1	G221E	Pathogenic	0.539
SLC26A4	O43511-1.1	G221F	Neutral	0.318
SLC26A4	O43511-1.1	G221H	Neutral	0.487
SLC26A4	O43511-1.1	G221I	Pathogenic	0.605
SLC26A4	O43511-1.1	G221K	Neutral	0.24
SLC26A4	O43511-1.1	G221L	Pathogenic	0.614
SLC26A4	O43511-1.1	G221M	Neutral	0.487
SLC26A4	O43511-1.1	G221N	Neutral	0.346
SLC26A4	O43511-1.1	G221P	Pathogenic	0.728
SLC26A4	O43511-1.1	G221Q	Pathogenic	0.523
SLC26A4	O43511-1.1	G221R	Neutral	0.149
SLC26A4	O43511-1.1	G221S	Pathogenic	0.65
SLC26A4	O43511-1.1	G221T	Pathogenic	0.736
SLC26A4	O43511-1.1	G221V	Pathogenic	0.693
SLC26A4	O43511-1.1	G221W	Neutral	0.052
SLC26A4	O43511-1.1	G221Y	Neutral	0.329
SLC26A4	O43511-1.1	G222A	Pathogenic	0.991
SLC26A4	O43511-1.1	G222C	Pathogenic	0.997
SLC26A4	O43511-1.1	G222D	Pathogenic	0.985
SLC26A4	O43511-1.1	G222E	Pathogenic	0.984
SLC26A4	O43511-1.1	G222F	Pathogenic	0.96
SLC26A4	O43511-1.1	G222H	Pathogenic	0.98
SLC26A4	O43511-1.1	G222I	Pathogenic	0.988
SLC26A4	O43511-1.1	G222K	Pathogenic	0.942
SLC26A4	O43511-1.1	G222L	Pathogenic	0.988
SLC26A4	O43511-1.1	G222M	Pathogenic	0.98
SLC26A4	O43511-1.1	G222N	Pathogenic	0.965
SLC26A4	O43511-1.1	G222P	Pathogenic	0.993
SLC26A4	O43511-1.1	G222Q	Pathogenic	0.983
SLC26A4	O43511-1.1	G222R	Pathogenic	0.9
SLC26A4	O43511-1.1	G222S	Pathogenic	0.99
SLC26A4	O43511-1.1	G222T	Pathogenic	0.993
SLC26A4	O43511-1.1	G222V	Pathogenic	0.991
SLC26A4	O43511-1.1	G222W	Pathogenic	0.739
SLC26A4	O43511-1.1	G222Y	Pathogenic	0.962
SLC26A4	O43511-1.1	F223A	Pathogenic	0.978
SLC26A4	O43511-1.1	F223C	Pathogenic	0.993
SLC26A4	O43511-1.1	F223D	Pathogenic	0.994
SLC26A4	O43511-1.1	F223E	Pathogenic	0.998
SLC26A4	O43511-1.1	F223G	Pathogenic	0.971
SLC26A4	O43511-1.1	F223H	Pathogenic	0.995
SLC26A4	O43511-1.1	F223I	Pathogenic	0.996
SLC26A4	O43511-1.1	F223K	Pathogenic	0.999
SLC26A4	O43511-1.1	F223L	Pathogenic	0.996
SLC26A4	O43511-1.1	F223M	Pathogenic	0.995
SLC26A4	O43511-1.1	F223N	Pathogenic	0.996
SLC26A4	O43511-1.1	F223P	Pathogenic	0.998
SLC26A4	O43511-1.1	F223Q	Pathogenic	0.998
SLC26A4	O43511-1.1	F223R	Pathogenic	0.998
SLC26A4	O43511-1.1	F223S	Pathogenic	0.981
SLC26A4	O43511-1.1	F223T	Pathogenic	0.993
SLC26A4	O43511-1.1	F223V	Pathogenic	0.994
SLC26A4	O43511-1.1	F223W	Pathogenic	0.98
SLC26A4	O43511-1.1	F223Y	Pathogenic	0.966
SLC26A4	O43511-1.1	T224A	Pathogenic	0.994
SLC26A4	O43511-1.1	T224C	Pathogenic	0.998
SLC26A4	O43511-1.1	T224D	Pathogenic	0.999
SLC26A4	O43511-1.1	T224E	Pathogenic	0.998
SLC26A4	O43511-1.1	T224F	Pathogenic	0.995
SLC26A4	O43511-1.1	T224G	Pathogenic	0.996
SLC26A4	O43511-1.1	T224H	Pathogenic	0.999
SLC26A4	O43511-1.1	T224I	Pathogenic	0.994
SLC26A4	O43511-1.1	T224K	Pathogenic	0.991
SLC26A4	O43511-1.1	T224L	Pathogenic	0.994
SLC26A4	O43511-1.1	T224M	Pathogenic	0.995
SLC26A4	O43511-1.1	T224N	Pathogenic	0.997
SLC26A4	O43511-1.1	T224P	Pathogenic	0.999
SLC26A4	O43511-1.1	T224Q	Pathogenic	0.997
SLC26A4	O43511-1.1	T224R	Pathogenic	0.984
SLC26A4	O43511-1.1	T224S	Pathogenic	0.991
SLC26A4	O43511-1.1	T224V	Pathogenic	0.996
SLC26A4	O43511-1.1	T224W	Pathogenic	0.979
SLC26A4	O43511-1.1	T224Y	Pathogenic	0.995
SLC26A4	O43511-1.1	T225A	Pathogenic	0.994
SLC26A4	O43511-1.1	T225C	Pathogenic	0.998
SLC26A4	O43511-1.1	T225D	Pathogenic	0.998
SLC26A4	O43511-1.1	T225E	Pathogenic	0.997
SLC26A4	O43511-1.1	T225F	Pathogenic	0.994
SLC26A4	O43511-1.1	T225G	Pathogenic	0.996
SLC26A4	O43511-1.1	T225H	Pathogenic	0.998
SLC26A4	O43511-1.1	T225I	Pathogenic	0.993
SLC26A4	O43511-1.1	T225K	Pathogenic	0.99
SLC26A4	O43511-1.1	T225L	Pathogenic	0.993
SLC26A4	O43511-1.1	T225M	Pathogenic	0.994
SLC26A4	O43511-1.1	T225N	Pathogenic	0.997
SLC26A4	O43511-1.1	T225P	Pathogenic	0.999
SLC26A4	O43511-1.1	T225Q	Pathogenic	0.997
SLC26A4	O43511-1.1	T225R	Pathogenic	0.982
SLC26A4	O43511-1.1	T225S	Pathogenic	0.99
SLC26A4	O43511-1.1	T225V	Pathogenic	0.995
SLC26A4	O43511-1.1	T225W	Pathogenic	0.977
SLC26A4	O43511-1.1	T225Y	Pathogenic	0.995
SLC26A4	O43511-1.1	A226C	Pathogenic	0.99
SLC26A4	O43511-1.1	A226D	Pathogenic	0.996
SLC26A4	O43511-1.1	A226E	Pathogenic	0.984
SLC26A4	O43511-1.1	A226F	Pathogenic	0.968
SLC26A4	O43511-1.1	A226G	Pathogenic	0.991
SLC26A4	O43511-1.1	A226H	Pathogenic	0.991
SLC26A4	O43511-1.1	A226I	Pathogenic	0.961
SLC26A4	O43511-1.1	A226K	Pathogenic	0.942
SLC26A4	O43511-1.1	A226L	Pathogenic	0.963
SLC26A4	O43511-1.1	A226M	Pathogenic	0.969
SLC26A4	O43511-1.1	A226N	Pathogenic	0.996
SLC26A4	O43511-1.1	A226P	Pathogenic	0.994
SLC26A4	O43511-1.1	A226Q	Pathogenic	0.983
SLC26A4	O43511-1.1	A226R	Pathogenic	0.9
SLC26A4	O43511-1.1	A226S	Pathogenic	0.99
SLC26A4	O43511-1.1	A226T	Pathogenic	0.989
SLC26A4	O43511-1.1	A226V	Pathogenic	0.973
SLC26A4	O43511-1.1	A226W	Pathogenic	0.936
SLC26A4	O43511-1.1	A226Y	Pathogenic	0.97
SLC26A4	O43511-1.1	A227C	Pathogenic	0.99
SLC26A4	O43511-1.1	A227D	Pathogenic	0.996
SLC26A4	O43511-1.1	A227E	Pathogenic	0.984
SLC26A4	O43511-1.1	A227F	Pathogenic	0.968
SLC26A4	O43511-1.1	A227G	Pathogenic	0.991
SLC26A4	O43511-1.1	A227H	Pathogenic	0.991
SLC26A4	O43511-1.1	A227I	Pathogenic	0.961
SLC26A4	O43511-1.1	A227K	Pathogenic	0.942
SLC26A4	O43511-1.1	A227L	Pathogenic	0.963
SLC26A4	O43511-1.1	A227M	Pathogenic	0.969
SLC26A4	O43511-1.1	A227N	Pathogenic	0.996
SLC26A4	O43511-1.1	A227P	Pathogenic	0.994
SLC26A4	O43511-1.1	A227Q	Pathogenic	0.983
SLC26A4	O43511-1.1	A227R	Pathogenic	0.9
SLC26A4	O43511-1.1	A227S	Pathogenic	0.99
SLC26A4	O43511-1.1	A227T	Pathogenic	0.989
SLC26A4	O43511-1.1	A227V	Pathogenic	0.973
SLC26A4	O43511-1.1	A227W	Pathogenic	0.936
SLC26A4	O43511-1.1	A227Y	Pathogenic	0.97
SLC26A4	O43511-1.1	A228C	Pathogenic	0.99
SLC26A4	O43511-1.1	A228D	Pathogenic	0.996
SLC26A4	O43511-1.1	A228E	Pathogenic	0.984
SLC26A4	O43511-1.1	A228F	Pathogenic	0.968
SLC26A4	O43511-1.1	A228G	Pathogenic	0.991
SLC26A4	O43511-1.1	A228H	Pathogenic	0.991
SLC26A4	O43511-1.1	A228I	Pathogenic	0.961
SLC26A4	O43511-1.1	A228K	Pathogenic	0.942
SLC26A4	O43511-1.1	A228L	Pathogenic	0.963
SLC26A4	O43511-1.1	A228M	Pathogenic	0.969
SLC26A4	O43511-1.1	A228N	Pathogenic	0.996
SLC26A4	O43511-1.1	A228P	Pathogenic	0.994
SLC26A4	O43511-1.1	A228Q	Pathogenic	0.983
SLC26A4	O43511-1.1	A228R	Pathogenic	0.9
SLC26A4	O43511-1.1	A228S	Pathogenic	0.99
SLC26A4	O43511-1.1	A228T	Pathogenic	0.989
SLC26A4	O43511-1.1	A228V	Pathogenic	0.973
SLC26A4	O43511-1.1	A228W	Pathogenic	0.936
SLC26A4	O43511-1.1	A228Y	Pathogenic	0.97
SLC26A4	O43511-1.1	F229A	Neutral	0.304
SLC26A4	O43511-1.1	F229C	Pathogenic	0.572
SLC26A4	O43511-1.1	F229D	Pathogenic	0.631
SLC26A4	O43511-1.1	F229E	Pathogenic	0.802
SLC26A4	O43511-1.1	F229G	Neutral	0.248
SLC26A4	O43511-1.1	F229H	Pathogenic	0.67
SLC26A4	O43511-1.1	F229I	Pathogenic	0.714
SLC26A4	O43511-1.1	F229K	Pathogenic	0.92
SLC26A4	O43511-1.1	F229L	Pathogenic	0.708
SLC26A4	O43511-1.1	F229M	Pathogenic	0.669
SLC26A4	O43511-1.1	F229N	Pathogenic	0.696
SLC26A4	O43511-1.1	F229P	Pathogenic	0.854
SLC26A4	O43511-1.1	F229Q	Pathogenic	0.857
SLC26A4	O43511-1.1	F229R	Pathogenic	0.864
SLC26A4	O43511-1.1	F229S	Neutral	0.334
SLC26A4	O43511-1.1	F229T	Pathogenic	0.581
SLC26A4	O43511-1.1	F229V	Pathogenic	0.632
SLC26A4	O43511-1.1	F229W	Neutral	0.327
SLC26A4	O43511-1.1	F229Y	Neutral	0.22
SLC26A4	O43511-1.1	Q230A	Pathogenic	0.854
SLC26A4	O43511-1.1	Q230C	Pathogenic	0.977
SLC26A4	O43511-1.1	Q230D	Pathogenic	0.895
SLC26A4	O43511-1.1	Q230E	Pathogenic	0.833
SLC26A4	O43511-1.1	Q230F	Pathogenic	0.977
SLC26A4	O43511-1.1	Q230G	Pathogenic	0.848
SLC26A4	O43511-1.1	Q230H	Pathogenic	0.956
SLC26A4	O43511-1.1	Q230I	Pathogenic	0.986
SLC26A4	O43511-1.1	Q230K	Pathogenic	0.81
SLC26A4	O43511-1.1	Q230L	Pathogenic	0.973
SLC26A4	O43511-1.1	Q230M	Pathogenic	0.915
SLC26A4	O43511-1.1	Q230N	Pathogenic	0.919
SLC26A4	O43511-1.1	Q230P	Pathogenic	0.934
SLC26A4	O43511-1.1	Q230R	Pathogenic	0.702
SLC26A4	O43511-1.1	Q230S	Pathogenic	0.813
SLC26A4	O43511-1.1	Q230T	Pathogenic	0.951
SLC26A4	O43511-1.1	Q230V	Pathogenic	0.979
SLC26A4	O43511-1.1	Q230W	Pathogenic	0.835
SLC26A4	O43511-1.1	Q230Y	Pathogenic	0.918
SLC26A4	O43511-1.1	V231A	Pathogenic	0.896
SLC26A4	O43511-1.1	V231C	Pathogenic	0.981
SLC26A4	O43511-1.1	V231D	Pathogenic	0.993
SLC26A4	O43511-1.1	V231E	Pathogenic	0.991
SLC26A4	O43511-1.1	V231F	Pathogenic	0.966
SLC26A4	O43511-1.1	V231G	Pathogenic	0.963
SLC26A4	O43511-1.1	V231H	Pathogenic	0.995
SLC26A4	O43511-1.1	V231I	Pathogenic	0.739
SLC26A4	O43511-1.1	V231K	Pathogenic	0.968
SLC26A4	O43511-1.1	V231L	Pathogenic	0.922
SLC26A4	O43511-1.1	V231M	Pathogenic	0.934
SLC26A4	O43511-1.1	V231N	Pathogenic	0.995
SLC26A4	O43511-1.1	V231P	Pathogenic	0.991
SLC26A4	O43511-1.1	V231Q	Pathogenic	0.991
SLC26A4	O43511-1.1	V231R	Pathogenic	0.971
SLC26A4	O43511-1.1	V231S	Pathogenic	0.976
SLC26A4	O43511-1.1	V231T	Pathogenic	0.965
SLC26A4	O43511-1.1	V231W	Pathogenic	0.964
SLC26A4	O43511-1.1	V231Y	Pathogenic	0.96
SLC26A4	O43511-1.1	L232A	Neutral	0.463
SLC26A4	O43511-1.1	L232C	Pathogenic	0.725
SLC26A4	O43511-1.1	L232D	Pathogenic	0.932
SLC26A4	O43511-1.1	L232E	Pathogenic	0.941
SLC26A4	O43511-1.1	L232F	Pathogenic	0.85
SLC26A4	O43511-1.1	L232G	Pathogenic	0.725
SLC26A4	O43511-1.1	L232H	Pathogenic	0.97
SLC26A4	O43511-1.1	L232I	Pathogenic	0.696
SLC26A4	O43511-1.1	L232K	Pathogenic	0.893
SLC26A4	O43511-1.1	L232M	Pathogenic	0.665
SLC26A4	O43511-1.1	L232N	Pathogenic	0.901
SLC26A4	O43511-1.1	L232P	Pathogenic	0.92
SLC26A4	O43511-1.1	L232Q	Pathogenic	0.922
SLC26A4	O43511-1.1	L232R	Pathogenic	0.822
SLC26A4	O43511-1.1	L232S	Pathogenic	0.665
SLC26A4	O43511-1.1	L232T	Pathogenic	0.732
SLC26A4	O43511-1.1	L232V	Pathogenic	0.628
SLC26A4	O43511-1.1	L232W	Pathogenic	0.844
SLC26A4	O43511-1.1	L232Y	Pathogenic	0.871
SLC26A4	O43511-1.1	V233A	Pathogenic	0.851
SLC26A4	O43511-1.1	V233C	Pathogenic	0.972
SLC26A4	O43511-1.1	V233D	Pathogenic	0.989
SLC26A4	O43511-1.1	V233E	Pathogenic	0.987
SLC26A4	O43511-1.1	V233F	Pathogenic	0.949
SLC26A4	O43511-1.1	V233G	Pathogenic	0.946
SLC26A4	O43511-1.1	V233H	Pathogenic	0.993
SLC26A4	O43511-1.1	V233I	Pathogenic	0.653
SLC26A4	O43511-1.1	V233K	Pathogenic	0.953
SLC26A4	O43511-1.1	V233L	Pathogenic	0.888
SLC26A4	O43511-1.1	V233M	Pathogenic	0.905
SLC26A4	O43511-1.1	V233N	Pathogenic	0.992
SLC26A4	O43511-1.1	V233P	Pathogenic	0.987
SLC26A4	O43511-1.1	V233Q	Pathogenic	0.986
SLC26A4	O43511-1.1	V233R	Pathogenic	0.957
SLC26A4	O43511-1.1	V233S	Pathogenic	0.964
SLC26A4	O43511-1.1	V233T	Pathogenic	0.948
SLC26A4	O43511-1.1	V233W	Pathogenic	0.947
SLC26A4	O43511-1.1	V233Y	Pathogenic	0.942
SLC26A4	O43511-1.1	S234A	Pathogenic	0.99
SLC26A4	O43511-1.1	S234C	Pathogenic	0.996
SLC26A4	O43511-1.1	S234D	Pathogenic	0.99
SLC26A4	O43511-1.1	S234E	Pathogenic	0.979
SLC26A4	O43511-1.1	S234F	Pathogenic	0.973
SLC26A4	O43511-1.1	S234G	Pathogenic	0.989
SLC26A4	O43511-1.1	S234H	Pathogenic	0.986
SLC26A4	O43511-1.1	S234I	Pathogenic	0.983
SLC26A4	O43511-1.1	S234K	Pathogenic	0.925
SLC26A4	O43511-1.1	S234L	Pathogenic	0.984
SLC26A4	O43511-1.1	S234M	Pathogenic	0.973
SLC26A4	O43511-1.1	S234N	Pathogenic	0.977
SLC26A4	O43511-1.1	S234P	Pathogenic	0.995
SLC26A4	O43511-1.1	S234Q	Pathogenic	0.977
SLC26A4	O43511-1.1	S234R	Pathogenic	0.932
SLC26A4	O43511-1.1	S234T	Pathogenic	0.981
SLC26A4	O43511-1.1	S234V	Pathogenic	0.994
SLC26A4	O43511-1.1	S234W	Pathogenic	0.944
SLC26A4	O43511-1.1	S234Y	Pathogenic	0.974
SLC26A4	O43511-1.1	Q235A	Pathogenic	0.996
SLC26A4	O43511-1.1	Q235C	Pathogenic	0.999
SLC26A4	O43511-1.1	Q235D	Pathogenic	0.997
SLC26A4	O43511-1.1	Q235E	Pathogenic	0.995
SLC26A4	O43511-1.1	Q235F	Pathogenic	0.999
SLC26A4	O43511-1.1	Q235G	Pathogenic	0.996
SLC26A4	O43511-1.1	Q235H	Pathogenic	0.999
SLC26A4	O43511-1.1	Q235I	Pathogenic	1.0
SLC26A4	O43511-1.1	Q235K	Pathogenic	0.994
SLC26A4	O43511-1.1	Q235L	Pathogenic	0.999
SLC26A4	O43511-1.1	Q235M	Pathogenic	0.998
SLC26A4	O43511-1.1	Q235N	Pathogenic	0.998
SLC26A4	O43511-1.1	Q235P	Pathogenic	0.998
SLC26A4	O43511-1.1	Q235R	Pathogenic	0.989
SLC26A4	O43511-1.1	Q235S	Pathogenic	0.994
SLC26A4	O43511-1.1	Q235T	Pathogenic	0.999
SLC26A4	O43511-1.1	Q235V	Pathogenic	0.999
SLC26A4	O43511-1.1	Q235W	Pathogenic	0.995
SLC26A4	O43511-1.1	Q235Y	Pathogenic	0.998
SLC26A4	O43511-1.1	L236A	Pathogenic	0.886
SLC26A4	O43511-1.1	L236C	Pathogenic	0.96
SLC26A4	O43511-1.1	L236D	Pathogenic	0.992
SLC26A4	O43511-1.1	L236E	Pathogenic	0.993
SLC26A4	O43511-1.1	L236F	Pathogenic	0.981
SLC26A4	O43511-1.1	L236G	Pathogenic	0.96
SLC26A4	O43511-1.1	L236H	Pathogenic	0.997
SLC26A4	O43511-1.1	L236I	Pathogenic	0.954
SLC26A4	O43511-1.1	L236K	Pathogenic	0.987
SLC26A4	O43511-1.1	L236M	Pathogenic	0.947
SLC26A4	O43511-1.1	L236N	Pathogenic	0.988
SLC26A4	O43511-1.1	L236P	Pathogenic	0.99
SLC26A4	O43511-1.1	L236Q	Pathogenic	0.991
SLC26A4	O43511-1.1	L236R	Pathogenic	0.977
SLC26A4	O43511-1.1	L236S	Pathogenic	0.947
SLC26A4	O43511-1.1	L236T	Pathogenic	0.961
SLC26A4	O43511-1.1	L236V	Pathogenic	0.938
SLC26A4	O43511-1.1	L236W	Pathogenic	0.98
SLC26A4	O43511-1.1	L236Y	Pathogenic	0.984
SLC26A4	O43511-1.1	K237A	Pathogenic	0.955
SLC26A4	O43511-1.1	K237C	Pathogenic	0.994
SLC26A4	O43511-1.1	K237D	Pathogenic	0.99
SLC26A4	O43511-1.1	K237E	Pathogenic	0.98
SLC26A4	O43511-1.1	K237F	Pathogenic	0.999
SLC26A4	O43511-1.1	K237G	Pathogenic	0.953
SLC26A4	O43511-1.1	K237H	Pathogenic	0.996
SLC26A4	O43511-1.1	K237I	Pathogenic	0.998
SLC26A4	O43511-1.1	K237L	Pathogenic	0.997
SLC26A4	O43511-1.1	K237M	Pathogenic	0.995
SLC26A4	O43511-1.1	K237N	Pathogenic	0.982
SLC26A4	O43511-1.1	K237P	Pathogenic	0.981
SLC26A4	O43511-1.1	K237Q	Pathogenic	0.982
SLC26A4	O43511-1.1	K237R	Pathogenic	0.981
SLC26A4	O43511-1.1	K237S	Pathogenic	0.94
SLC26A4	O43511-1.1	K237T	Pathogenic	0.986
SLC26A4	O43511-1.1	K237V	Pathogenic	0.994
SLC26A4	O43511-1.1	K237W	Pathogenic	0.996
SLC26A4	O43511-1.1	K237Y	Pathogenic	0.998
SLC26A4	O43511-1.1	I238A	Neutral	0.176
SLC26A4	O43511-1.1	I238C	Neutral	0.395
SLC26A4	O43511-1.1	I238D	Pathogenic	0.627
SLC26A4	O43511-1.1	I238E	Pathogenic	0.8
SLC26A4	O43511-1.1	I238F	Pathogenic	0.6
SLC26A4	O43511-1.1	I238G	Neutral	0.395
SLC26A4	O43511-1.1	I238H	Pathogenic	0.89
SLC26A4	O43511-1.1	I238K	Pathogenic	0.807
SLC26A4	O43511-1.1	I238L	Neutral	0.371
SLC26A4	O43511-1.1	I238M	Neutral	0.498
SLC26A4	O43511-1.1	I238N	Pathogenic	0.692
SLC26A4	O43511-1.1	I238P	Pathogenic	0.74
SLC26A4	O43511-1.1	I238Q	Pathogenic	0.854
SLC26A4	O43511-1.1	I238R	Pathogenic	0.698
SLC26A4	O43511-1.1	I238S	Neutral	0.33
SLC26A4	O43511-1.1	I238T	Neutral	0.404
SLC26A4	O43511-1.1	I238V	Neutral	0.094
SLC26A4	O43511-1.1	I238W	Pathogenic	0.744
SLC26A4	O43511-1.1	I238Y	Pathogenic	0.626
SLC26A4	O43511-1.1	V239A	Neutral	0.167
SLC26A4	O43511-1.1	V239C	Pathogenic	0.551
SLC26A4	O43511-1.1	V239D	Pathogenic	0.76
SLC26A4	O43511-1.1	V239E	Pathogenic	0.722
SLC26A4	O43511-1.1	V239F	Neutral	0.396
SLC26A4	O43511-1.1	V239G	Neutral	0.379
SLC26A4	O43511-1.1	V239H	Pathogenic	0.824
SLC26A4	O43511-1.1	V239I	Neutral	0.062
SLC26A4	O43511-1.1	V239K	Neutral	0.413
SLC26A4	O43511-1.1	V239L	Neutral	0.217
SLC26A4	O43511-1.1	V239M	Neutral	0.249
SLC26A4	O43511-1.1	V239N	Pathogenic	0.809
SLC26A4	O43511-1.1	V239P	Pathogenic	0.728
SLC26A4	O43511-1.1	V239Q	Pathogenic	0.709
SLC26A4	O43511-1.1	V239R	Neutral	0.438
SLC26A4	O43511-1.1	V239S	Neutral	0.481
SLC26A4	O43511-1.1	V239T	Neutral	0.388
SLC26A4	O43511-1.1	V239W	Neutral	0.385
SLC26A4	O43511-1.1	V239Y	Neutral	0.361
SLC26A4	O43511-1.1	L240A	Pathogenic	0.79
SLC26A4	O43511-1.1	L240C	Pathogenic	0.92
SLC26A4	O43511-1.1	L240D	Pathogenic	0.984
SLC26A4	O43511-1.1	L240E	Pathogenic	0.986
SLC26A4	O43511-1.1	L240F	Pathogenic	0.961
SLC26A4	O43511-1.1	L240G	Pathogenic	0.92
SLC26A4	O43511-1.1	L240H	Pathogenic	0.993
SLC26A4	O43511-1.1	L240I	Pathogenic	0.909
SLC26A4	O43511-1.1	L240K	Pathogenic	0.973
SLC26A4	O43511-1.1	L240M	Pathogenic	0.897
SLC26A4	O43511-1.1	L240N	Pathogenic	0.975
SLC26A4	O43511-1.1	L240P	Pathogenic	0.981
SLC26A4	O43511-1.1	L240Q	Pathogenic	0.981
SLC26A4	O43511-1.1	L240R	Pathogenic	0.953
SLC26A4	O43511-1.1	L240S	Pathogenic	0.897
SLC26A4	O43511-1.1	L240T	Pathogenic	0.923
SLC26A4	O43511-1.1	L240V	Pathogenic	0.881
SLC26A4	O43511-1.1	L240W	Pathogenic	0.959
SLC26A4	O43511-1.1	L240Y	Pathogenic	0.967
SLC26A4	O43511-1.1	N241A	Pathogenic	0.916
SLC26A4	O43511-1.1	N241C	Pathogenic	0.976
SLC26A4	O43511-1.1	N241D	Pathogenic	0.841
SLC26A4	O43511-1.1	N241E	Pathogenic	0.886
SLC26A4	O43511-1.1	N241F	Pathogenic	0.888
SLC26A4	O43511-1.1	N241G	Pathogenic	0.564
SLC26A4	O43511-1.1	N241H	Pathogenic	0.664
SLC26A4	O43511-1.1	N241I	Pathogenic	0.928
SLC26A4	O43511-1.1	N241K	Pathogenic	0.678
SLC26A4	O43511-1.1	N241L	Pathogenic	0.931
SLC26A4	O43511-1.1	N241M	Pathogenic	0.889
SLC26A4	O43511-1.1	N241P	Pathogenic	0.963
SLC26A4	O43511-1.1	N241Q	Pathogenic	0.845
SLC26A4	O43511-1.1	N241R	Pathogenic	0.538
SLC26A4	O43511-1.1	N241S	Pathogenic	0.669
SLC26A4	O43511-1.1	N241T	Pathogenic	0.899
SLC26A4	O43511-1.1	N241V	Pathogenic	0.974
SLC26A4	O43511-1.1	N241W	Pathogenic	0.79
SLC26A4	O43511-1.1	N241Y	Pathogenic	0.805
SLC26A4	O43511-1.1	V242A	Neutral	0.304
SLC26A4	O43511-1.1	V242C	Pathogenic	0.729
SLC26A4	O43511-1.1	V242D	Pathogenic	0.874
SLC26A4	O43511-1.1	V242E	Pathogenic	0.851
SLC26A4	O43511-1.1	V242F	Pathogenic	0.59
SLC26A4	O43511-1.1	V242G	Pathogenic	0.572
SLC26A4	O43511-1.1	V242H	Pathogenic	0.911
SLC26A4	O43511-1.1	V242I	Neutral	0.126
SLC26A4	O43511-1.1	V242K	Pathogenic	0.606
SLC26A4	O43511-1.1	V242L	Neutral	0.377
SLC26A4	O43511-1.1	V242M	Neutral	0.42
SLC26A4	O43511-1.1	V242N	Pathogenic	0.902
SLC26A4	O43511-1.1	V242P	Pathogenic	0.854
SLC26A4	O43511-1.1	V242Q	Pathogenic	0.842
SLC26A4	O43511-1.1	V242R	Pathogenic	0.631
SLC26A4	O43511-1.1	V242S	Pathogenic	0.67
SLC26A4	O43511-1.1	V242T	Pathogenic	0.581
SLC26A4	O43511-1.1	V242W	Pathogenic	0.578
SLC26A4	O43511-1.1	V242Y	Pathogenic	0.553
SLC26A4	O43511-1.1	S243A	Neutral	0.316
SLC26A4	O43511-1.1	S243C	Pathogenic	0.512
SLC26A4	O43511-1.1	S243D	Neutral	0.317
SLC26A4	O43511-1.1	S243E	Neutral	0.178
SLC26A4	O43511-1.1	S243F	Neutral	0.144
SLC26A4	O43511-1.1	S243G	Neutral	0.307
SLC26A4	O43511-1.1	S243H	Neutral	0.255
SLC26A4	O43511-1.1	S243I	Neutral	0.216
SLC26A4	O43511-1.1	S243K	Neutral	0.055
SLC26A4	O43511-1.1	S243L	Neutral	0.223
SLC26A4	O43511-1.1	S243M	Neutral	0.146
SLC26A4	O43511-1.1	S243N	Neutral	0.164
SLC26A4	O43511-1.1	S243P	Neutral	0.492
SLC26A4	O43511-1.1	S243Q	Neutral	0.169
SLC26A4	O43511-1.1	S243R	Neutral	0.061
SLC26A4	O43511-1.1	S243T	Neutral	0.2
SLC26A4	O43511-1.1	S243V	Neutral	0.449
SLC26A4	O43511-1.1	S243W	Neutral	0.074
SLC26A4	O43511-1.1	S243Y	Neutral	0.151
SLC26A4	O43511-1.1	T244A	Pathogenic	0.894
SLC26A4	O43511-1.1	T244C	Pathogenic	0.969
SLC26A4	O43511-1.1	T244D	Pathogenic	0.972
SLC26A4	O43511-1.1	T244E	Pathogenic	0.951
SLC26A4	O43511-1.1	T244F	Pathogenic	0.904
SLC26A4	O43511-1.1	T244G	Pathogenic	0.93
SLC26A4	O43511-1.1	T244H	Pathogenic	0.972
SLC26A4	O43511-1.1	T244I	Pathogenic	0.884
SLC26A4	O43511-1.1	T244K	Pathogenic	0.839
SLC26A4	O43511-1.1	T244L	Pathogenic	0.888
SLC26A4	O43511-1.1	T244M	Pathogenic	0.905
SLC26A4	O43511-1.1	T244N	Pathogenic	0.946
SLC26A4	O43511-1.1	T244P	Pathogenic	0.976
SLC26A4	O43511-1.1	T244Q	Pathogenic	0.948
SLC26A4	O43511-1.1	T244R	Pathogenic	0.742
SLC26A4	O43511-1.1	T244S	Pathogenic	0.834
SLC26A4	O43511-1.1	T244V	Pathogenic	0.918
SLC26A4	O43511-1.1	T244W	Pathogenic	0.689
SLC26A4	O43511-1.1	T244Y	Pathogenic	0.908
SLC26A4	O43511-1.1	K245A	Neutral	0.114
SLC26A4	O43511-1.1	K245C	Neutral	0.485
SLC26A4	O43511-1.1	K245D	Neutral	0.365
SLC26A4	O43511-1.1	K245E	Neutral	0.234
SLC26A4	O43511-1.1	K245F	Pathogenic	0.863
SLC26A4	O43511-1.1	K245G	Neutral	0.11
SLC26A4	O43511-1.1	K245H	Pathogenic	0.579
SLC26A4	O43511-1.1	K245I	Pathogenic	0.792
SLC26A4	O43511-1.1	K245L	Pathogenic	0.664
SLC26A4	O43511-1.1	K245M	Pathogenic	0.541
SLC26A4	O43511-1.1	K245N	Neutral	0.251
SLC26A4	O43511-1.1	K245P	Neutral	0.236
SLC26A4	O43511-1.1	K245Q	Neutral	0.245
SLC26A4	O43511-1.1	K245R	Neutral	0.237
SLC26A4	O43511-1.1	K245S	Neutral	0.087
SLC26A4	O43511-1.1	K245T	Neutral	0.297
SLC26A4	O43511-1.1	K245V	Pathogenic	0.502
SLC26A4	O43511-1.1	K245W	Pathogenic	0.598
SLC26A4	O43511-1.1	K245Y	Pathogenic	0.767
SLC26A4	O43511-1.1	N246A	Pathogenic	0.791
SLC26A4	O43511-1.1	N246C	Pathogenic	0.933
SLC26A4	O43511-1.1	N246D	Pathogenic	0.647
SLC26A4	O43511-1.1	N246E	Pathogenic	0.73
SLC26A4	O43511-1.1	N246F	Pathogenic	0.732
SLC26A4	O43511-1.1	N246G	Neutral	0.309
SLC26A4	O43511-1.1	N246H	Neutral	0.407
SLC26A4	O43511-1.1	N246I	Pathogenic	0.817
SLC26A4	O43511-1.1	N246K	Neutral	0.422
SLC26A4	O43511-1.1	N246L	Pathogenic	0.823
SLC26A4	O43511-1.1	N246M	Pathogenic	0.735
SLC26A4	O43511-1.1	N246P	Pathogenic	0.901
SLC26A4	O43511-1.1	N246Q	Pathogenic	0.654
SLC26A4	O43511-1.1	N246R	Neutral	0.288
SLC26A4	O43511-1.1	N246S	Neutral	0.411
SLC26A4	O43511-1.1	N246T	Pathogenic	0.756
SLC26A4	O43511-1.1	N246V	Pathogenic	0.93
SLC26A4	O43511-1.1	N246W	Pathogenic	0.565
SLC26A4	O43511-1.1	N246Y	Pathogenic	0.588
SLC26A4	O43511-1.1	Y247A	Pathogenic	0.703
SLC26A4	O43511-1.1	Y247C	Pathogenic	0.877
SLC26A4	O43511-1.1	Y247D	Pathogenic	0.902
SLC26A4	O43511-1.1	Y247E	Pathogenic	0.916
SLC26A4	O43511-1.1	Y247F	Pathogenic	0.592
SLC26A4	O43511-1.1	Y247G	Pathogenic	0.641
SLC26A4	O43511-1.1	Y247H	Pathogenic	0.575
SLC26A4	O43511-1.1	Y247I	Pathogenic	0.935
SLC26A4	O43511-1.1	Y247K	Pathogenic	0.969
SLC26A4	O43511-1.1	Y247L	Pathogenic	0.937
SLC26A4	O43511-1.1	Y247M	Pathogenic	0.947
SLC26A4	O43511-1.1	Y247N	Pathogenic	0.86
SLC26A4	O43511-1.1	Y247P	Pathogenic	0.94
SLC26A4	O43511-1.1	Y247Q	Pathogenic	0.889
SLC26A4	O43511-1.1	Y247R	Pathogenic	0.967
SLC26A4	O43511-1.1	Y247S	Pathogenic	0.731
SLC26A4	O43511-1.1	Y247T	Pathogenic	0.882
SLC26A4	O43511-1.1	Y247V	Pathogenic	0.884
SLC26A4	O43511-1.1	Y247W	Pathogenic	0.543
SLC26A4	O43511-1.1	N248A	Pathogenic	0.951
SLC26A4	O43511-1.1	N248C	Pathogenic	0.986
SLC26A4	O43511-1.1	N248D	Pathogenic	0.904
SLC26A4	O43511-1.1	N248E	Pathogenic	0.933
SLC26A4	O43511-1.1	N248F	Pathogenic	0.934
SLC26A4	O43511-1.1	N248G	Pathogenic	0.698
SLC26A4	O43511-1.1	N248H	Pathogenic	0.779
SLC26A4	O43511-1.1	N248I	Pathogenic	0.958
SLC26A4	O43511-1.1	N248K	Pathogenic	0.79
SLC26A4	O43511-1.1	N248L	Pathogenic	0.96
SLC26A4	O43511-1.1	N248M	Pathogenic	0.935
SLC26A4	O43511-1.1	N248P	Pathogenic	0.979
SLC26A4	O43511-1.1	N248Q	Pathogenic	0.907
SLC26A4	O43511-1.1	N248R	Pathogenic	0.675
SLC26A4	O43511-1.1	N248S	Pathogenic	0.783
SLC26A4	O43511-1.1	N248T	Pathogenic	0.941
SLC26A4	O43511-1.1	N248V	Pathogenic	0.986
SLC26A4	O43511-1.1	N248W	Pathogenic	0.87
SLC26A4	O43511-1.1	N248Y	Pathogenic	0.88
SLC26A4	O43511-1.1	G249A	Pathogenic	0.799
SLC26A4	O43511-1.1	G249C	Pathogenic	0.914
SLC26A4	O43511-1.1	G249D	Pathogenic	0.694
SLC26A4	O43511-1.1	G249E	Pathogenic	0.68
SLC26A4	O43511-1.1	G249F	Neutral	0.459
SLC26A4	O43511-1.1	G249H	Pathogenic	0.633
SLC26A4	O43511-1.1	G249I	Pathogenic	0.736
SLC26A4	O43511-1.1	G249K	Neutral	0.365
SLC26A4	O43511-1.1	G249L	Pathogenic	0.743
SLC26A4	O43511-1.1	G249M	Pathogenic	0.633
SLC26A4	O43511-1.1	G249N	Neutral	0.49
SLC26A4	O43511-1.1	G249P	Pathogenic	0.829
SLC26A4	O43511-1.1	G249Q	Pathogenic	0.666
SLC26A4	O43511-1.1	G249R	Neutral	0.241
SLC26A4	O43511-1.1	G249S	Pathogenic	0.771
SLC26A4	O43511-1.1	G249T	Pathogenic	0.835
SLC26A4	O43511-1.1	G249V	Pathogenic	0.804
SLC26A4	O43511-1.1	G249W	Neutral	0.091
SLC26A4	O43511-1.1	G249Y	Neutral	0.471
SLC26A4	O43511-1.1	V250A	Neutral	0.137
SLC26A4	O43511-1.1	V250C	Neutral	0.495
SLC26A4	O43511-1.1	V250D	Pathogenic	0.716
SLC26A4	O43511-1.1	V250E	Pathogenic	0.674
SLC26A4	O43511-1.1	V250F	Neutral	0.343
SLC26A4	O43511-1.1	V250G	Neutral	0.327
SLC26A4	O43511-1.1	V250H	Pathogenic	0.789
SLC26A4	O43511-1.1	V250I	Neutral	0.05
SLC26A4	O43511-1.1	V250K	Neutral	0.359
SLC26A4	O43511-1.1	V250L	Neutral	0.18
SLC26A4	O43511-1.1	V250M	Neutral	0.209
SLC26A4	O43511-1.1	V250N	Pathogenic	0.771
SLC26A4	O43511-1.1	V250P	Pathogenic	0.68
SLC26A4	O43511-1.1	V250Q	Pathogenic	0.66
SLC26A4	O43511-1.1	V250R	Neutral	0.383
SLC26A4	O43511-1.1	V250S	Neutral	0.425
SLC26A4	O43511-1.1	V250T	Neutral	0.336
SLC26A4	O43511-1.1	V250W	Neutral	0.333
SLC26A4	O43511-1.1	V250Y	Neutral	0.311
SLC26A4	O43511-1.1	L251A	Pathogenic	0.503
SLC26A4	O43511-1.1	L251C	Pathogenic	0.755
SLC26A4	O43511-1.1	L251D	Pathogenic	0.941
SLC26A4	O43511-1.1	L251E	Pathogenic	0.95
SLC26A4	O43511-1.1	L251F	Pathogenic	0.869
SLC26A4	O43511-1.1	L251G	Pathogenic	0.755
SLC26A4	O43511-1.1	L251H	Pathogenic	0.974
SLC26A4	O43511-1.1	L251I	Pathogenic	0.729
SLC26A4	O43511-1.1	L251K	Pathogenic	0.908
SLC26A4	O43511-1.1	L251M	Pathogenic	0.7
SLC26A4	O43511-1.1	L251N	Pathogenic	0.914
SLC26A4	O43511-1.1	L251P	Pathogenic	0.931
SLC26A4	O43511-1.1	L251Q	Pathogenic	0.933
SLC26A4	O43511-1.1	L251R	Pathogenic	0.844
SLC26A4	O43511-1.1	L251S	Pathogenic	0.7
SLC26A4	O43511-1.1	L251T	Pathogenic	0.762
SLC26A4	O43511-1.1	L251V	Pathogenic	0.664
SLC26A4	O43511-1.1	L251W	Pathogenic	0.864
SLC26A4	O43511-1.1	L251Y	Pathogenic	0.888
SLC26A4	O43511-1.1	S252A	Pathogenic	0.94
SLC26A4	O43511-1.1	S252C	Pathogenic	0.973
SLC26A4	O43511-1.1	S252D	Pathogenic	0.94
SLC26A4	O43511-1.1	S252E	Pathogenic	0.88
SLC26A4	O43511-1.1	S252F	Pathogenic	0.851
SLC26A4	O43511-1.1	S252G	Pathogenic	0.938
SLC26A4	O43511-1.1	S252H	Pathogenic	0.921
SLC26A4	O43511-1.1	S252I	Pathogenic	0.903
SLC26A4	O43511-1.1	S252K	Pathogenic	0.665
SLC26A4	O43511-1.1	S252L	Pathogenic	0.907
SLC26A4	O43511-1.1	S252M	Pathogenic	0.853
SLC26A4	O43511-1.1	S252N	Pathogenic	0.87
SLC26A4	O43511-1.1	S252P	Pathogenic	0.97
SLC26A4	O43511-1.1	S252Q	Pathogenic	0.873
SLC26A4	O43511-1.1	S252R	Pathogenic	0.688
SLC26A4	O43511-1.1	S252T	Pathogenic	0.895
SLC26A4	O43511-1.1	S252V	Pathogenic	0.965
SLC26A4	O43511-1.1	S252W	Pathogenic	0.731
SLC26A4	O43511-1.1	S252Y	Pathogenic	0.857
SLC26A4	O43511-1.1	I253A	Pathogenic	0.765
SLC26A4	O43511-1.1	I253C	Pathogenic	0.909
SLC26A4	O43511-1.1	I253D	Pathogenic	0.962
SLC26A4	O43511-1.1	I253E	Pathogenic	0.984
SLC26A4	O43511-1.1	I253F	Pathogenic	0.958
SLC26A4	O43511-1.1	I253G	Pathogenic	0.909
SLC26A4	O43511-1.1	I253H	Pathogenic	0.992
SLC26A4	O43511-1.1	I253K	Pathogenic	0.984
SLC26A4	O43511-1.1	I253L	Pathogenic	0.9
SLC26A4	O43511-1.1	I253M	Pathogenic	0.938
SLC26A4	O43511-1.1	I253N	Pathogenic	0.972
SLC26A4	O43511-1.1	I253P	Pathogenic	0.977
SLC26A4	O43511-1.1	I253Q	Pathogenic	0.989
SLC26A4	O43511-1.1	I253R	Pathogenic	0.972
SLC26A4	O43511-1.1	I253S	Pathogenic	0.882
SLC26A4	O43511-1.1	I253T	Pathogenic	0.912
SLC26A4	O43511-1.1	I253V	Pathogenic	0.612
SLC26A4	O43511-1.1	I253W	Pathogenic	0.978
SLC26A4	O43511-1.1	I253Y	Pathogenic	0.962
SLC26A4	O43511-1.1	I254A	Neutral	0.427
SLC26A4	O43511-1.1	I254C	Pathogenic	0.695
SLC26A4	O43511-1.1	I254D	Pathogenic	0.854
SLC26A4	O43511-1.1	I254E	Pathogenic	0.933
SLC26A4	O43511-1.1	I254F	Pathogenic	0.84
SLC26A4	O43511-1.1	I254G	Pathogenic	0.695
SLC26A4	O43511-1.1	I254H	Pathogenic	0.966
SLC26A4	O43511-1.1	I254K	Pathogenic	0.936
SLC26A4	O43511-1.1	I254L	Pathogenic	0.673
SLC26A4	O43511-1.1	I254M	Pathogenic	0.775
SLC26A4	O43511-1.1	I254N	Pathogenic	0.887
SLC26A4	O43511-1.1	I254P	Pathogenic	0.909
SLC26A4	O43511-1.1	I254Q	Pathogenic	0.953
SLC26A4	O43511-1.1	I254R	Pathogenic	0.889
SLC26A4	O43511-1.1	I254S	Pathogenic	0.632
SLC26A4	O43511-1.1	I254T	Pathogenic	0.703
SLC26A4	O43511-1.1	I254V	Neutral	0.265
SLC26A4	O43511-1.1	I254W	Pathogenic	0.91
SLC26A4	O43511-1.1	I254Y	Pathogenic	0.854
SLC26A4	O43511-1.1	Y255A	Pathogenic	0.964
SLC26A4	O43511-1.1	Y255C	Pathogenic	0.988
SLC26A4	O43511-1.1	Y255D	Pathogenic	0.991
SLC26A4	O43511-1.1	Y255E	Pathogenic	0.992
SLC26A4	O43511-1.1	Y255F	Pathogenic	0.943
SLC26A4	O43511-1.1	Y255G	Pathogenic	0.953
SLC26A4	O43511-1.1	Y255H	Pathogenic	0.939
SLC26A4	O43511-1.1	Y255I	Pathogenic	0.994
SLC26A4	O43511-1.1	Y255K	Pathogenic	0.997
SLC26A4	O43511-1.1	Y255L	Pathogenic	0.994
SLC26A4	O43511-1.1	Y255M	Pathogenic	0.995
SLC26A4	O43511-1.1	Y255N	Pathogenic	0.986
SLC26A4	O43511-1.1	Y255P	Pathogenic	0.994
SLC26A4	O43511-1.1	Y255Q	Pathogenic	0.989
SLC26A4	O43511-1.1	Y255R	Pathogenic	0.997
SLC26A4	O43511-1.1	Y255S	Pathogenic	0.969
SLC26A4	O43511-1.1	Y255T	Pathogenic	0.988
SLC26A4	O43511-1.1	Y255V	Pathogenic	0.989
SLC26A4	O43511-1.1	Y255W	Pathogenic	0.931
SLC26A4	O43511-1.1	T256A	Pathogenic	0.927
SLC26A4	O43511-1.1	T256C	Pathogenic	0.979
SLC26A4	O43511-1.1	T256D	Pathogenic	0.981
SLC26A4	O43511-1.1	T256E	Pathogenic	0.967
SLC26A4	O43511-1.1	T256F	Pathogenic	0.934
SLC26A4	O43511-1.1	T256G	Pathogenic	0.953
SLC26A4	O43511-1.1	T256H	Pathogenic	0.981
SLC26A4	O43511-1.1	T256I	Pathogenic	0.92
SLC26A4	O43511-1.1	T256K	Pathogenic	0.886
SLC26A4	O43511-1.1	T256L	Pathogenic	0.922
SLC26A4	O43511-1.1	T256M	Pathogenic	0.934
SLC26A4	O43511-1.1	T256N	Pathogenic	0.963
SLC26A4	O43511-1.1	T256P	Pathogenic	0.984
SLC26A4	O43511-1.1	T256Q	Pathogenic	0.964
SLC26A4	O43511-1.1	T256R	Pathogenic	0.812
SLC26A4	O43511-1.1	T256S	Pathogenic	0.883
SLC26A4	O43511-1.1	T256V	Pathogenic	0.944
SLC26A4	O43511-1.1	T256W	Pathogenic	0.769
SLC26A4	O43511-1.1	T256Y	Pathogenic	0.936
SLC26A4	O43511-1.1	L257A	Pathogenic	0.866
SLC26A4	O43511-1.1	L257C	Pathogenic	0.952
SLC26A4	O43511-1.1	L257D	Pathogenic	0.99
SLC26A4	O43511-1.1	L257E	Pathogenic	0.992
SLC26A4	O43511-1.1	L257F	Pathogenic	0.977
SLC26A4	O43511-1.1	L257G	Pathogenic	0.952
SLC26A4	O43511-1.1	L257H	Pathogenic	0.996
SLC26A4	O43511-1.1	L257I	Pathogenic	0.945
SLC26A4	O43511-1.1	L257K	Pathogenic	0.984
SLC26A4	O43511-1.1	L257M	Pathogenic	0.937
SLC26A4	O43511-1.1	L257N	Pathogenic	0.985
SLC26A4	O43511-1.1	L257P	Pathogenic	0.989
SLC26A4	O43511-1.1	L257Q	Pathogenic	0.989
SLC26A4	O43511-1.1	L257R	Pathogenic	0.972
SLC26A4	O43511-1.1	L257S	Pathogenic	0.937
SLC26A4	O43511-1.1	L257T	Pathogenic	0.953
SLC26A4	O43511-1.1	L257V	Pathogenic	0.926
SLC26A4	O43511-1.1	L257W	Pathogenic	0.976
SLC26A4	O43511-1.1	L257Y	Pathogenic	0.981
SLC26A4	O43511-1.1	V258A	Neutral	0.008
SLC26A4	O43511-1.1	V258C	Neutral	0.05
SLC26A4	O43511-1.1	V258D	Neutral	0.119
SLC26A4	O43511-1.1	V258E	Neutral	0.1
SLC26A4	O43511-1.1	V258F	Neutral	0.027
SLC26A4	O43511-1.1	V258G	Neutral	0.025
SLC26A4	O43511-1.1	V258H	Neutral	0.167
SLC26A4	O43511-1.1	V258I	Neutral	0.003
SLC26A4	O43511-1.1	V258K	Neutral	0.029
SLC26A4	O43511-1.1	V258L	Neutral	0.012
SLC26A4	O43511-1.1	V258M	Neutral	0.014
SLC26A4	O43511-1.1	V258N	Neutral	0.153
SLC26A4	O43511-1.1	V258P	Neutral	0.103
SLC26A4	O43511-1.1	V258Q	Neutral	0.095
SLC26A4	O43511-1.1	V258R	Neutral	0.032
SLC26A4	O43511-1.1	V258S	Neutral	0.038
SLC26A4	O43511-1.1	V258T	Neutral	0.026
SLC26A4	O43511-1.1	V258W	Neutral	0.026
SLC26A4	O43511-1.1	V258Y	Neutral	0.024
SLC26A4	O43511-1.1	E259A	Neutral	0.375
SLC26A4	O43511-1.1	E259C	Pathogenic	0.898
SLC26A4	O43511-1.1	E259D	Neutral	0.23
SLC26A4	O43511-1.1	E259F	Pathogenic	0.738
SLC26A4	O43511-1.1	E259G	Neutral	0.365
SLC26A4	O43511-1.1	E259H	Pathogenic	0.586
SLC26A4	O43511-1.1	E259I	Pathogenic	0.821
SLC26A4	O43511-1.1	E259K	Neutral	0.278
SLC26A4	O43511-1.1	E259L	Pathogenic	0.827
SLC26A4	O43511-1.1	E259M	Pathogenic	0.741
SLC26A4	O43511-1.1	E259N	Pathogenic	0.611
SLC26A4	O43511-1.1	E259P	Pathogenic	0.591
SLC26A4	O43511-1.1	E259Q	Neutral	0.325
SLC26A4	O43511-1.1	E259R	Neutral	0.299
SLC26A4	O43511-1.1	E259S	Neutral	0.309
SLC26A4	O43511-1.1	E259T	Pathogenic	0.664
SLC26A4	O43511-1.1	E259V	Pathogenic	0.825
SLC26A4	O43511-1.1	E259W	Neutral	0.4
SLC26A4	O43511-1.1	E259Y	Pathogenic	0.595
SLC26A4	O43511-1.1	I260A	Neutral	0.289
SLC26A4	O43511-1.1	I260C	Pathogenic	0.555
SLC26A4	O43511-1.1	I260D	Pathogenic	0.762
SLC26A4	O43511-1.1	I260E	Pathogenic	0.884
SLC26A4	O43511-1.1	I260F	Pathogenic	0.741
SLC26A4	O43511-1.1	I260G	Pathogenic	0.554
SLC26A4	O43511-1.1	I260H	Pathogenic	0.939
SLC26A4	O43511-1.1	I260K	Pathogenic	0.888
SLC26A4	O43511-1.1	I260L	Pathogenic	0.53
SLC26A4	O43511-1.1	I260M	Pathogenic	0.654
SLC26A4	O43511-1.1	I260N	Pathogenic	0.811
SLC26A4	O43511-1.1	I260P	Pathogenic	0.845
SLC26A4	O43511-1.1	I260Q	Pathogenic	0.918
SLC26A4	O43511-1.1	I260R	Pathogenic	0.815
SLC26A4	O43511-1.1	I260S	Neutral	0.484
SLC26A4	O43511-1.1	I260T	Pathogenic	0.563
SLC26A4	O43511-1.1	I260V	Neutral	0.165
SLC26A4	O43511-1.1	I260W	Pathogenic	0.847
SLC26A4	O43511-1.1	I260Y	Pathogenic	0.761
SLC26A4	O43511-1.1	F261A	Pathogenic	0.96
SLC26A4	O43511-1.1	F261C	Pathogenic	0.986
SLC26A4	O43511-1.1	F261D	Pathogenic	0.989
SLC26A4	O43511-1.1	F261E	Pathogenic	0.996
SLC26A4	O43511-1.1	F261G	Pathogenic	0.948
SLC26A4	O43511-1.1	F261H	Pathogenic	0.991
SLC26A4	O43511-1.1	F261I	Pathogenic	0.993
SLC26A4	O43511-1.1	F261K	Pathogenic	0.998
SLC26A4	O43511-1.1	F261L	Pathogenic	0.993
SLC26A4	O43511-1.1	F261M	Pathogenic	0.991
SLC26A4	O43511-1.1	F261N	Pathogenic	0.992
SLC26A4	O43511-1.1	F261P	Pathogenic	0.997
SLC26A4	O43511-1.1	F261Q	Pathogenic	0.997
SLC26A4	O43511-1.1	F261R	Pathogenic	0.997
SLC26A4	O43511-1.1	F261S	Pathogenic	0.965
SLC26A4	O43511-1.1	F261T	Pathogenic	0.987
SLC26A4	O43511-1.1	F261V	Pathogenic	0.989
SLC26A4	O43511-1.1	F261W	Pathogenic	0.964
SLC26A4	O43511-1.1	F261Y	Pathogenic	0.939
SLC26A4	O43511-1.1	Q262A	Neutral	0.235
SLC26A4	O43511-1.1	Q262C	Pathogenic	0.692
SLC26A4	O43511-1.1	Q262D	Neutral	0.309
SLC26A4	O43511-1.1	Q262E	Neutral	0.208
SLC26A4	O43511-1.1	Q262F	Pathogenic	0.693
SLC26A4	O43511-1.1	Q262G	Neutral	0.227
SLC26A4	O43511-1.1	Q262H	Pathogenic	0.532
SLC26A4	O43511-1.1	Q262I	Pathogenic	0.787
SLC26A4	O43511-1.1	Q262K	Neutral	0.183
SLC26A4	O43511-1.1	Q262L	Pathogenic	0.657
SLC26A4	O43511-1.1	Q262M	Neutral	0.362
SLC26A4	O43511-1.1	Q262N	Neutral	0.374
SLC26A4	O43511-1.1	Q262P	Neutral	0.425
SLC26A4	O43511-1.1	Q262R	Neutral	0.11
SLC26A4	O43511-1.1	Q262S	Neutral	0.186
SLC26A4	O43511-1.1	Q262T	Pathogenic	0.503
SLC26A4	O43511-1.1	Q262V	Pathogenic	0.707
SLC26A4	O43511-1.1	Q262W	Neutral	0.21
SLC26A4	O43511-1.1	Q262Y	Neutral	0.37
SLC26A4	O43511-1.1	N263A	Pathogenic	0.839
SLC26A4	O43511-1.1	N263C	Pathogenic	0.95
SLC26A4	O43511-1.1	N263D	Pathogenic	0.716
SLC26A4	O43511-1.1	N263E	Pathogenic	0.788
SLC26A4	O43511-1.1	N263F	Pathogenic	0.79
SLC26A4	O43511-1.1	N263G	Neutral	0.381
SLC26A4	O43511-1.1	N263H	Neutral	0.485
SLC26A4	O43511-1.1	N263I	Pathogenic	0.86
SLC26A4	O43511-1.1	N263K	Pathogenic	0.501
SLC26A4	O43511-1.1	N263L	Pathogenic	0.865
SLC26A4	O43511-1.1	N263M	Pathogenic	0.792
SLC26A4	O43511-1.1	N263P	Pathogenic	0.926
SLC26A4	O43511-1.1	N263Q	Pathogenic	0.722
SLC26A4	O43511-1.1	N263R	Neutral	0.357
SLC26A4	O43511-1.1	N263S	Neutral	0.49
SLC26A4	O43511-1.1	N263T	Pathogenic	0.81
SLC26A4	O43511-1.1	N263V	Pathogenic	0.948
SLC26A4	O43511-1.1	N263W	Pathogenic	0.641
SLC26A4	O43511-1.1	N263Y	Pathogenic	0.663
SLC26A4	O43511-1.1	I264A	Pathogenic	0.868
SLC26A4	O43511-1.1	I264C	Pathogenic	0.952
SLC26A4	O43511-1.1	I264D	Pathogenic	0.981
SLC26A4	O43511-1.1	I264E	Pathogenic	0.992
SLC26A4	O43511-1.1	I264F	Pathogenic	0.979
SLC26A4	O43511-1.1	I264G	Pathogenic	0.952
SLC26A4	O43511-1.1	I264H	Pathogenic	0.996
SLC26A4	O43511-1.1	I264K	Pathogenic	0.992
SLC26A4	O43511-1.1	I264L	Pathogenic	0.948
SLC26A4	O43511-1.1	I264M	Pathogenic	0.968
SLC26A4	O43511-1.1	I264N	Pathogenic	0.986
SLC26A4	O43511-1.1	I264P	Pathogenic	0.989
SLC26A4	O43511-1.1	I264Q	Pathogenic	0.994
SLC26A4	O43511-1.1	I264R	Pathogenic	0.986
SLC26A4	O43511-1.1	I264S	Pathogenic	0.938
SLC26A4	O43511-1.1	I264T	Pathogenic	0.954
SLC26A4	O43511-1.1	I264V	Pathogenic	0.76
SLC26A4	O43511-1.1	I264W	Pathogenic	0.989
SLC26A4	O43511-1.1	I264Y	Pathogenic	0.981
SLC26A4	O43511-1.1	G265A	Neutral	0.222
SLC26A4	O43511-1.1	G265C	Neutral	0.43
SLC26A4	O43511-1.1	G265D	Neutral	0.139
SLC26A4	O43511-1.1	G265E	Neutral	0.132
SLC26A4	O43511-1.1	G265F	Neutral	0.057
SLC26A4	O43511-1.1	G265H	Neutral	0.11
SLC26A4	O43511-1.1	G265I	Neutral	0.166
SLC26A4	O43511-1.1	G265K	Neutral	0.039
SLC26A4	O43511-1.1	G265L	Neutral	0.171
SLC26A4	O43511-1.1	G265M	Neutral	0.11
SLC26A4	O43511-1.1	G265N	Neutral	0.064
SLC26A4	O43511-1.1	G265P	Neutral	0.258
SLC26A4	O43511-1.1	G265Q	Neutral	0.125
SLC26A4	O43511-1.1	G265R	Neutral	0.022
SLC26A4	O43511-1.1	G265S	Neutral	0.194
SLC26A4	O43511-1.1	G265T	Neutral	0.266
SLC26A4	O43511-1.1	G265V	Neutral	0.226
SLC26A4	O43511-1.1	G265W	Neutral	0.007
SLC26A4	O43511-1.1	G265Y	Neutral	0.06
SLC26A4	O43511-1.1	D266A	Neutral	0.1
SLC26A4	O43511-1.1	D266C	Neutral	0.288
SLC26A4	O43511-1.1	D266E	Neutral	0.013
SLC26A4	O43511-1.1	D266F	Neutral	0.049
SLC26A4	O43511-1.1	D266G	Neutral	0.026
SLC26A4	O43511-1.1	D266H	Neutral	0.049
SLC26A4	O43511-1.1	D266I	Neutral	0.077
SLC26A4	O43511-1.1	D266K	Neutral	0.03
SLC26A4	O43511-1.1	D266L	Neutral	0.148
SLC26A4	O43511-1.1	D266M	Neutral	0.094
SLC26A4	O43511-1.1	D266N	Neutral	0.044
SLC26A4	O43511-1.1	D266P	Neutral	0.117
SLC26A4	O43511-1.1	D266Q	Neutral	0.034
SLC26A4	O43511-1.1	D266R	Neutral	0.033
SLC26A4	O43511-1.1	D266S	Neutral	0.04
SLC26A4	O43511-1.1	D266T	Neutral	0.132
SLC26A4	O43511-1.1	D266V	Neutral	0.198
SLC26A4	O43511-1.1	D266W	Neutral	0.024
SLC26A4	O43511-1.1	D266Y	Neutral	0.051
SLC26A4	O43511-1.1	T267A	Pathogenic	0.991
SLC26A4	O43511-1.1	T267C	Pathogenic	0.998
SLC26A4	O43511-1.1	T267D	Pathogenic	0.998
SLC26A4	O43511-1.1	T267E	Pathogenic	0.996
SLC26A4	O43511-1.1	T267F	Pathogenic	0.992
SLC26A4	O43511-1.1	T267G	Pathogenic	0.994
SLC26A4	O43511-1.1	T267H	Pathogenic	0.998
SLC26A4	O43511-1.1	T267I	Pathogenic	0.99
SLC26A4	O43511-1.1	T267K	Pathogenic	0.986
SLC26A4	O43511-1.1	T267L	Pathogenic	0.99
SLC26A4	O43511-1.1	T267M	Pathogenic	0.992
SLC26A4	O43511-1.1	T267N	Pathogenic	0.996
SLC26A4	O43511-1.1	T267P	Pathogenic	0.998
SLC26A4	O43511-1.1	T267Q	Pathogenic	0.996
SLC26A4	O43511-1.1	T267R	Pathogenic	0.974
SLC26A4	O43511-1.1	T267S	Pathogenic	0.985
SLC26A4	O43511-1.1	T267V	Pathogenic	0.993
SLC26A4	O43511-1.1	T267W	Pathogenic	0.967
SLC26A4	O43511-1.1	T267Y	Pathogenic	0.992
SLC26A4	O43511-1.1	N268A	Pathogenic	0.999
SLC26A4	O43511-1.1	N268C	Pathogenic	1.0
SLC26A4	O43511-1.1	N268D	Pathogenic	0.997
SLC26A4	O43511-1.1	N268E	Pathogenic	0.998
SLC26A4	O43511-1.1	N268F	Pathogenic	0.998
SLC26A4	O43511-1.1	N268G	Pathogenic	0.99
SLC26A4	O43511-1.1	N268H	Pathogenic	0.993
SLC26A4	O43511-1.1	N268I	Pathogenic	0.999
SLC26A4	O43511-1.1	N268K	Pathogenic	0.994
SLC26A4	O43511-1.1	N268L	Pathogenic	0.999
SLC26A4	O43511-1.1	N268M	Pathogenic	0.998
SLC26A4	O43511-1.1	N268P	Pathogenic	0.999
SLC26A4	O43511-1.1	N268Q	Pathogenic	0.998
SLC26A4	O43511-1.1	N268R	Pathogenic	0.989
SLC26A4	O43511-1.1	N268S	Pathogenic	0.993
SLC26A4	O43511-1.1	N268T	Pathogenic	0.999
SLC26A4	O43511-1.1	N268V	Pathogenic	1.0
SLC26A4	O43511-1.1	N268W	Pathogenic	0.996
SLC26A4	O43511-1.1	N268Y	Pathogenic	0.997
SLC26A4	O43511-1.1	L269A	Neutral	0.055
SLC26A4	O43511-1.1	L269C	Neutral	0.152
SLC26A4	O43511-1.1	L269D	Neutral	0.481
SLC26A4	O43511-1.1	L269E	Pathogenic	0.523
SLC26A4	O43511-1.1	L269F	Neutral	0.278
SLC26A4	O43511-1.1	L269G	Neutral	0.152
SLC26A4	O43511-1.1	L269H	Pathogenic	0.689
SLC26A4	O43511-1.1	L269I	Neutral	0.135
SLC26A4	O43511-1.1	L269K	Neutral	0.363
SLC26A4	O43511-1.1	L269M	Neutral	0.119
SLC26A4	O43511-1.1	L269N	Neutral	0.382
SLC26A4	O43511-1.1	L269P	Neutral	0.439
SLC26A4	O43511-1.1	L269Q	Neutral	0.445
SLC26A4	O43511-1.1	L269R	Neutral	0.24
SLC26A4	O43511-1.1	L269S	Neutral	0.119
SLC26A4	O43511-1.1	L269T	Neutral	0.157
SLC26A4	O43511-1.1	L269V	Neutral	0.103
SLC26A4	O43511-1.1	L269W	Neutral	0.269
SLC26A4	O43511-1.1	L269Y	Neutral	0.315
SLC26A4	O43511-1.1	A270C	Pathogenic	0.972
SLC26A4	O43511-1.1	A270D	Pathogenic	0.99
SLC26A4	O43511-1.1	A270E	Pathogenic	0.957
SLC26A4	O43511-1.1	A270F	Pathogenic	0.919
SLC26A4	O43511-1.1	A270G	Pathogenic	0.976
SLC26A4	O43511-1.1	A270H	Pathogenic	0.976
SLC26A4	O43511-1.1	A270I	Pathogenic	0.902
SLC26A4	O43511-1.1	A270K	Pathogenic	0.859
SLC26A4	O43511-1.1	A270L	Pathogenic	0.906
SLC26A4	O43511-1.1	A270M	Pathogenic	0.92
SLC26A4	O43511-1.1	A270N	Pathogenic	0.988
SLC26A4	O43511-1.1	A270P	Pathogenic	0.985
SLC26A4	O43511-1.1	A270Q	Pathogenic	0.955
SLC26A4	O43511-1.1	A270R	Pathogenic	0.77
SLC26A4	O43511-1.1	A270S	Pathogenic	0.973
SLC26A4	O43511-1.1	A270T	Pathogenic	0.97
SLC26A4	O43511-1.1	A270V	Pathogenic	0.931
SLC26A4	O43511-1.1	A270W	Pathogenic	0.844
SLC26A4	O43511-1.1	A270Y	Pathogenic	0.923
SLC26A4	O43511-1.1	D271A	Pathogenic	0.996
SLC26A4	O43511-1.1	D271C	Pathogenic	0.999
SLC26A4	O43511-1.1	D271E	Pathogenic	0.963
SLC26A4	O43511-1.1	D271F	Pathogenic	0.99
SLC26A4	O43511-1.1	D271G	Pathogenic	0.982
SLC26A4	O43511-1.1	D271H	Pathogenic	0.991
SLC26A4	O43511-1.1	D271I	Pathogenic	0.994
SLC26A4	O43511-1.1	D271K	Pathogenic	0.985
SLC26A4	O43511-1.1	D271L	Pathogenic	0.997
SLC26A4	O43511-1.1	D271M	Pathogenic	0.995
SLC26A4	O43511-1.1	D271N	Pathogenic	0.989
SLC26A4	O43511-1.1	D271P	Pathogenic	0.996
SLC26A4	O43511-1.1	D271Q	Pathogenic	0.986
SLC26A4	O43511-1.1	D271R	Pathogenic	0.986
SLC26A4	O43511-1.1	D271S	Pathogenic	0.988
SLC26A4	O43511-1.1	D271T	Pathogenic	0.997
SLC26A4	O43511-1.1	D271V	Pathogenic	0.998
SLC26A4	O43511-1.1	D271W	Pathogenic	0.98
SLC26A4	O43511-1.1	D271Y	Pathogenic	0.991
SLC26A4	O43511-1.1	F272A	Neutral	0.272
SLC26A4	O43511-1.1	F272C	Pathogenic	0.533
SLC26A4	O43511-1.1	F272D	Pathogenic	0.594
SLC26A4	O43511-1.1	F272E	Pathogenic	0.776
SLC26A4	O43511-1.1	F272G	Neutral	0.221
SLC26A4	O43511-1.1	F272H	Pathogenic	0.635
SLC26A4	O43511-1.1	F272I	Pathogenic	0.681
SLC26A4	O43511-1.1	F272K	Pathogenic	0.907
SLC26A4	O43511-1.1	F272L	Pathogenic	0.675
SLC26A4	O43511-1.1	F272M	Pathogenic	0.634
SLC26A4	O43511-1.1	F272N	Pathogenic	0.662
SLC26A4	O43511-1.1	F272P	Pathogenic	0.833
SLC26A4	O43511-1.1	F272Q	Pathogenic	0.836
SLC26A4	O43511-1.1	F272R	Pathogenic	0.844
SLC26A4	O43511-1.1	F272S	Neutral	0.3
SLC26A4	O43511-1.1	F272T	Pathogenic	0.542
SLC26A4	O43511-1.1	F272V	Pathogenic	0.595
SLC26A4	O43511-1.1	F272W	Neutral	0.293
SLC26A4	O43511-1.1	F272Y	Neutral	0.194
SLC26A4	O43511-1.1	T273A	Neutral	0.039
SLC26A4	O43511-1.1	T273C	Neutral	0.129
SLC26A4	O43511-1.1	T273D	Neutral	0.141
SLC26A4	O43511-1.1	T273E	Neutral	0.084
SLC26A4	O43511-1.1	T273F	Neutral	0.043
SLC26A4	O43511-1.1	T273G	Neutral	0.06
SLC26A4	O43511-1.1	T273H	Neutral	0.142
SLC26A4	O43511-1.1	T273I	Neutral	0.035
SLC26A4	O43511-1.1	T273K	Neutral	0.024
SLC26A4	O43511-1.1	T273L	Neutral	0.036
SLC26A4	O43511-1.1	T273M	Neutral	0.043
SLC26A4	O43511-1.1	T273N	Neutral	0.077
SLC26A4	O43511-1.1	T273P	Neutral	0.164
SLC26A4	O43511-1.1	T273Q	Neutral	0.079
SLC26A4	O43511-1.1	T273R	Neutral	0.014
SLC26A4	O43511-1.1	T273S	Neutral	0.023
SLC26A4	O43511-1.1	T273V	Neutral	0.051
SLC26A4	O43511-1.1	T273W	Neutral	0.01
SLC26A4	O43511-1.1	T273Y	Neutral	0.045
SLC26A4	O43511-1.1	A274C	Neutral	0.465
SLC26A4	O43511-1.1	A274D	Pathogenic	0.706
SLC26A4	O43511-1.1	A274E	Neutral	0.358
SLC26A4	O43511-1.1	A274F	Neutral	0.22
SLC26A4	O43511-1.1	A274G	Pathogenic	0.5
SLC26A4	O43511-1.1	A274H	Pathogenic	0.501
SLC26A4	O43511-1.1	A274I	Neutral	0.186
SLC26A4	O43511-1.1	A274K	Neutral	0.131
SLC26A4	O43511-1.1	A274L	Neutral	0.192
SLC26A4	O43511-1.1	A274M	Neutral	0.222
SLC26A4	O43511-1.1	A274N	Pathogenic	0.671
SLC26A4	O43511-1.1	A274P	Pathogenic	0.618
SLC26A4	O43511-1.1	A274Q	Neutral	0.343
SLC26A4	O43511-1.1	A274R	Neutral	0.077
SLC26A4	O43511-1.1	A274S	Neutral	0.469
SLC26A4	O43511-1.1	A274T	Neutral	0.446
SLC26A4	O43511-1.1	A274V	Neutral	0.252
SLC26A4	O43511-1.1	A274W	Neutral	0.118
SLC26A4	O43511-1.1	A274Y	Neutral	0.228
SLC26A4	O43511-1.1	G275A	Pathogenic	0.756
SLC26A4	O43511-1.1	G275C	Pathogenic	0.892
SLC26A4	O43511-1.1	G275D	Pathogenic	0.638
SLC26A4	O43511-1.1	G275E	Pathogenic	0.624
SLC26A4	O43511-1.1	G275F	Neutral	0.398
SLC26A4	O43511-1.1	G275H	Pathogenic	0.573
SLC26A4	O43511-1.1	G275I	Pathogenic	0.684
SLC26A4	O43511-1.1	G275K	Neutral	0.309
SLC26A4	O43511-1.1	G275L	Pathogenic	0.693
SLC26A4	O43511-1.1	G275M	Pathogenic	0.574
SLC26A4	O43511-1.1	G275N	Neutral	0.428
SLC26A4	O43511-1.1	G275P	Pathogenic	0.791
SLC26A4	O43511-1.1	G275Q	Pathogenic	0.608
SLC26A4	O43511-1.1	G275R	Neutral	0.198
SLC26A4	O43511-1.1	G275S	Pathogenic	0.724
SLC26A4	O43511-1.1	G275T	Pathogenic	0.798
SLC26A4	O43511-1.1	G275V	Pathogenic	0.761
SLC26A4	O43511-1.1	G275W	Neutral	0.072
SLC26A4	O43511-1.1	G275Y	Neutral	0.409
SLC26A4	O43511-1.1	L276A	Pathogenic	0.801
SLC26A4	O43511-1.1	L276C	Pathogenic	0.925
SLC26A4	O43511-1.1	L276D	Pathogenic	0.985
SLC26A4	O43511-1.1	L276E	Pathogenic	0.987
SLC26A4	O43511-1.1	L276F	Pathogenic	0.963
SLC26A4	O43511-1.1	L276G	Pathogenic	0.925
SLC26A4	O43511-1.1	L276H	Pathogenic	0.993
SLC26A4	O43511-1.1	L276I	Pathogenic	0.914
SLC26A4	O43511-1.1	L276K	Pathogenic	0.975
SLC26A4	O43511-1.1	L276M	Pathogenic	0.903
SLC26A4	O43511-1.1	L276N	Pathogenic	0.977
SLC26A4	O43511-1.1	L276P	Pathogenic	0.982
SLC26A4	O43511-1.1	L276Q	Pathogenic	0.982
SLC26A4	O43511-1.1	L276R	Pathogenic	0.956
SLC26A4	O43511-1.1	L276S	Pathogenic	0.903
SLC26A4	O43511-1.1	L276T	Pathogenic	0.927
SLC26A4	O43511-1.1	L276V	Pathogenic	0.887
SLC26A4	O43511-1.1	L276W	Pathogenic	0.962
SLC26A4	O43511-1.1	L276Y	Pathogenic	0.969
SLC26A4	O43511-1.1	L277A	Neutral	0.091
SLC26A4	O43511-1.1	L277C	Neutral	0.234
SLC26A4	O43511-1.1	L277D	Pathogenic	0.613
SLC26A4	O43511-1.1	L277E	Pathogenic	0.651
SLC26A4	O43511-1.1	L277F	Neutral	0.396
SLC26A4	O43511-1.1	L277G	Neutral	0.234
SLC26A4	O43511-1.1	L277H	Pathogenic	0.79
SLC26A4	O43511-1.1	L277I	Neutral	0.21
SLC26A4	O43511-1.1	L277K	Neutral	0.493
SLC26A4	O43511-1.1	L277M	Neutral	0.188
SLC26A4	O43511-1.1	L277N	Pathogenic	0.513
SLC26A4	O43511-1.1	L277P	Pathogenic	0.572
SLC26A4	O43511-1.1	L277Q	Pathogenic	0.578
SLC26A4	O43511-1.1	L277R	Neutral	0.35
SLC26A4	O43511-1.1	L277S	Neutral	0.187
SLC26A4	O43511-1.1	L277T	Neutral	0.241
SLC26A4	O43511-1.1	L277V	Neutral	0.164
SLC26A4	O43511-1.1	L277W	Neutral	0.385
SLC26A4	O43511-1.1	L277Y	Neutral	0.439
SLC26A4	O43511-1.1	T278A	Pathogenic	0.556
SLC26A4	O43511-1.1	T278C	Pathogenic	0.821
SLC26A4	O43511-1.1	T278D	Pathogenic	0.836
SLC26A4	O43511-1.1	T278E	Pathogenic	0.741
SLC26A4	O43511-1.1	T278F	Pathogenic	0.581
SLC26A4	O43511-1.1	T278G	Pathogenic	0.665
SLC26A4	O43511-1.1	T278H	Pathogenic	0.837
SLC26A4	O43511-1.1	T278I	Pathogenic	0.53
SLC26A4	O43511-1.1	T278K	Neutral	0.436
SLC26A4	O43511-1.1	T278L	Pathogenic	0.54
SLC26A4	O43511-1.1	T278M	Pathogenic	0.585
SLC26A4	O43511-1.1	T278N	Pathogenic	0.722
SLC26A4	O43511-1.1	T278P	Pathogenic	0.859
SLC26A4	O43511-1.1	T278Q	Pathogenic	0.728
SLC26A4	O43511-1.1	T278R	Neutral	0.299
SLC26A4	O43511-1.1	T278S	Neutral	0.427
SLC26A4	O43511-1.1	T278V	Pathogenic	0.624
SLC26A4	O43511-1.1	T278W	Neutral	0.247
SLC26A4	O43511-1.1	T278Y	Pathogenic	0.593
SLC26A4	O43511-1.1	I279A	Neutral	0.165
SLC26A4	O43511-1.1	I279C	Neutral	0.377
SLC26A4	O43511-1.1	I279D	Pathogenic	0.609
SLC26A4	O43511-1.1	I279E	Pathogenic	0.787
SLC26A4	O43511-1.1	I279F	Pathogenic	0.582
SLC26A4	O43511-1.1	I279G	Neutral	0.377
SLC26A4	O43511-1.1	I279H	Pathogenic	0.882
SLC26A4	O43511-1.1	I279K	Pathogenic	0.795
SLC26A4	O43511-1.1	I279L	Neutral	0.354
SLC26A4	O43511-1.1	I279M	Neutral	0.479
SLC26A4	O43511-1.1	I279N	Pathogenic	0.676
SLC26A4	O43511-1.1	I279P	Pathogenic	0.726
SLC26A4	O43511-1.1	I279Q	Pathogenic	0.845
SLC26A4	O43511-1.1	I279R	Pathogenic	0.681
SLC26A4	O43511-1.1	I279S	Neutral	0.314
SLC26A4	O43511-1.1	I279T	Neutral	0.386
SLC26A4	O43511-1.1	I279V	Neutral	0.088
SLC26A4	O43511-1.1	I279W	Pathogenic	0.73
SLC26A4	O43511-1.1	I279Y	Pathogenic	0.608
SLC26A4	O43511-1.1	V280A	Neutral	0.067
SLC26A4	O43511-1.1	V280C	Neutral	0.305
SLC26A4	O43511-1.1	V280D	Pathogenic	0.53
SLC26A4	O43511-1.1	V280E	Neutral	0.481
SLC26A4	O43511-1.1	V280F	Neutral	0.19
SLC26A4	O43511-1.1	V280G	Neutral	0.179
SLC26A4	O43511-1.1	V280H	Pathogenic	0.626
SLC26A4	O43511-1.1	V280I	Neutral	0.023
SLC26A4	O43511-1.1	V280K	Neutral	0.2
SLC26A4	O43511-1.1	V280L	Neutral	0.09
SLC26A4	O43511-1.1	V280M	Neutral	0.106
SLC26A4	O43511-1.1	V280N	Pathogenic	0.601
SLC26A4	O43511-1.1	V280P	Neutral	0.488
SLC26A4	O43511-1.1	V280Q	Neutral	0.465
SLC26A4	O43511-1.1	V280R	Neutral	0.218
SLC26A4	O43511-1.1	V280S	Neutral	0.248
SLC26A4	O43511-1.1	V280T	Neutral	0.184
SLC26A4	O43511-1.1	V280W	Neutral	0.183
SLC26A4	O43511-1.1	V280Y	Neutral	0.168
SLC26A4	O43511-1.1	V281A	Neutral	0.177
SLC26A4	O43511-1.1	V281C	Pathogenic	0.569
SLC26A4	O43511-1.1	V281D	Pathogenic	0.773
SLC26A4	O43511-1.1	V281E	Pathogenic	0.736
SLC26A4	O43511-1.1	V281F	Neutral	0.414
SLC26A4	O43511-1.1	V281G	Neutral	0.396
SLC26A4	O43511-1.1	V281H	Pathogenic	0.834
SLC26A4	O43511-1.1	V281I	Neutral	0.066
SLC26A4	O43511-1.1	V281K	Neutral	0.43
SLC26A4	O43511-1.1	V281L	Neutral	0.229
SLC26A4	O43511-1.1	V281M	Neutral	0.262
SLC26A4	O43511-1.1	V281N	Pathogenic	0.82
SLC26A4	O43511-1.1	V281P	Pathogenic	0.742
SLC26A4	O43511-1.1	V281Q	Pathogenic	0.724
SLC26A4	O43511-1.1	V281R	Neutral	0.456
SLC26A4	O43511-1.1	V281S	Neutral	0.499
SLC26A4	O43511-1.1	V281T	Neutral	0.405
SLC26A4	O43511-1.1	V281W	Neutral	0.402
SLC26A4	O43511-1.1	V281Y	Neutral	0.378
SLC26A4	O43511-1.1	C282A	Pathogenic	0.974
SLC26A4	O43511-1.1	C282D	Pathogenic	0.997
SLC26A4	O43511-1.1	C282E	Pathogenic	0.997
SLC26A4	O43511-1.1	C282F	Pathogenic	0.974
SLC26A4	O43511-1.1	C282G	Pathogenic	0.991
SLC26A4	O43511-1.1	C282H	Pathogenic	0.994
SLC26A4	O43511-1.1	C282I	Pathogenic	0.969
SLC26A4	O43511-1.1	C282K	Pathogenic	0.98
SLC26A4	O43511-1.1	C282L	Pathogenic	0.97
SLC26A4	O43511-1.1	C282M	Pathogenic	0.975
SLC26A4	O43511-1.1	C282N	Pathogenic	0.997
SLC26A4	O43511-1.1	C282P	Pathogenic	0.999
SLC26A4	O43511-1.1	C282Q	Pathogenic	0.994
SLC26A4	O43511-1.1	C282R	Pathogenic	0.964
SLC26A4	O43511-1.1	C282S	Pathogenic	0.989
SLC26A4	O43511-1.1	C282T	Pathogenic	0.992
SLC26A4	O43511-1.1	C282V	Pathogenic	0.989
SLC26A4	O43511-1.1	C282W	Pathogenic	0.899
SLC26A4	O43511-1.1	C282Y	Pathogenic	0.975
SLC26A4	O43511-1.1	M283A	Pathogenic	0.727
SLC26A4	O43511-1.1	M283C	Pathogenic	0.891
SLC26A4	O43511-1.1	M283D	Pathogenic	0.954
SLC26A4	O43511-1.1	M283E	Pathogenic	0.961
SLC26A4	O43511-1.1	M283F	Pathogenic	0.924
SLC26A4	O43511-1.1	M283G	Pathogenic	0.802
SLC26A4	O43511-1.1	M283H	Pathogenic	0.98
SLC26A4	O43511-1.1	M283I	Pathogenic	0.908
SLC26A4	O43511-1.1	M283K	Pathogenic	0.928
SLC26A4	O43511-1.1	M283L	Pathogenic	0.837
SLC26A4	O43511-1.1	M283N	Pathogenic	0.933
SLC26A4	O43511-1.1	M283P	Pathogenic	0.946
SLC26A4	O43511-1.1	M283Q	Pathogenic	0.9
SLC26A4	O43511-1.1	M283R	Pathogenic	0.877
SLC26A4	O43511-1.1	M283S	Pathogenic	0.753
SLC26A4	O43511-1.1	M283T	Pathogenic	0.894
SLC26A4	O43511-1.1	M283V	Pathogenic	0.839
SLC26A4	O43511-1.1	M283W	Pathogenic	0.852
SLC26A4	O43511-1.1	M283Y	Pathogenic	0.954
SLC26A4	O43511-1.1	A284C	Neutral	0.264
SLC26A4	O43511-1.1	A284D	Neutral	0.497
SLC26A4	O43511-1.1	A284E	Neutral	0.187
SLC26A4	O43511-1.1	A284F	Neutral	0.104
SLC26A4	O43511-1.1	A284G	Neutral	0.292
SLC26A4	O43511-1.1	A284H	Neutral	0.293
SLC26A4	O43511-1.1	A284I	Neutral	0.086
SLC26A4	O43511-1.1	A284K	Neutral	0.058
SLC26A4	O43511-1.1	A284L	Neutral	0.089
SLC26A4	O43511-1.1	A284M	Neutral	0.105
SLC26A4	O43511-1.1	A284N	Neutral	0.457
SLC26A4	O43511-1.1	A284P	Neutral	0.4
SLC26A4	O43511-1.1	A284Q	Neutral	0.177
SLC26A4	O43511-1.1	A284R	Neutral	0.033
SLC26A4	O43511-1.1	A284S	Neutral	0.267
SLC26A4	O43511-1.1	A284T	Neutral	0.25
SLC26A4	O43511-1.1	A284V	Neutral	0.122
SLC26A4	O43511-1.1	A284W	Neutral	0.052
SLC26A4	O43511-1.1	A284Y	Neutral	0.109
SLC26A4	O43511-1.1	V285A	Pathogenic	0.869
SLC26A4	O43511-1.1	V285C	Pathogenic	0.976
SLC26A4	O43511-1.1	V285D	Pathogenic	0.991
SLC26A4	O43511-1.1	V285E	Pathogenic	0.989
SLC26A4	O43511-1.1	V285F	Pathogenic	0.956
SLC26A4	O43511-1.1	V285G	Pathogenic	0.953
SLC26A4	O43511-1.1	V285H	Pathogenic	0.994
SLC26A4	O43511-1.1	V285I	Pathogenic	0.686
SLC26A4	O43511-1.1	V285K	Pathogenic	0.959
SLC26A4	O43511-1.1	V285L	Pathogenic	0.902
SLC26A4	O43511-1.1	V285M	Pathogenic	0.917
SLC26A4	O43511-1.1	V285N	Pathogenic	0.993
SLC26A4	O43511-1.1	V285P	Pathogenic	0.989
SLC26A4	O43511-1.1	V285Q	Pathogenic	0.988
SLC26A4	O43511-1.1	V285R	Pathogenic	0.963
SLC26A4	O43511-1.1	V285S	Pathogenic	0.969
SLC26A4	O43511-1.1	V285T	Pathogenic	0.955
SLC26A4	O43511-1.1	V285W	Pathogenic	0.954
SLC26A4	O43511-1.1	V285Y	Pathogenic	0.949
SLC26A4	O43511-1.1	K286A	Pathogenic	0.973
SLC26A4	O43511-1.1	K286C	Pathogenic	0.996
SLC26A4	O43511-1.1	K286D	Pathogenic	0.994
SLC26A4	O43511-1.1	K286E	Pathogenic	0.988
SLC26A4	O43511-1.1	K286F	Pathogenic	0.999
SLC26A4	O43511-1.1	K286G	Pathogenic	0.972
SLC26A4	O43511-1.1	K286H	Pathogenic	0.997
SLC26A4	O43511-1.1	K286I	Pathogenic	0.999
SLC26A4	O43511-1.1	K286L	Pathogenic	0.998
SLC26A4	O43511-1.1	K286M	Pathogenic	0.997
SLC26A4	O43511-1.1	K286N	Pathogenic	0.989
SLC26A4	O43511-1.1	K286P	Pathogenic	0.988
SLC26A4	O43511-1.1	K286Q	Pathogenic	0.989
SLC26A4	O43511-1.1	K286R	Pathogenic	0.989
SLC26A4	O43511-1.1	K286S	Pathogenic	0.964
SLC26A4	O43511-1.1	K286T	Pathogenic	0.992
SLC26A4	O43511-1.1	K286V	Pathogenic	0.996
SLC26A4	O43511-1.1	K286W	Pathogenic	0.998
SLC26A4	O43511-1.1	K286Y	Pathogenic	0.999
SLC26A4	O43511-1.1	E287A	Pathogenic	0.995
SLC26A4	O43511-1.1	E287C	Pathogenic	1.0
SLC26A4	O43511-1.1	E287D	Pathogenic	0.989
SLC26A4	O43511-1.1	E287F	Pathogenic	0.999
SLC26A4	O43511-1.1	E287G	Pathogenic	0.994
SLC26A4	O43511-1.1	E287H	Pathogenic	0.998
SLC26A4	O43511-1.1	E287I	Pathogenic	0.999
SLC26A4	O43511-1.1	E287K	Pathogenic	0.991
SLC26A4	O43511-1.1	E287L	Pathogenic	0.999
SLC26A4	O43511-1.1	E287M	Pathogenic	0.999
SLC26A4	O43511-1.1	E287N	Pathogenic	0.998
SLC26A4	O43511-1.1	E287P	Pathogenic	0.998
SLC26A4	O43511-1.1	E287Q	Pathogenic	0.993
SLC26A4	O43511-1.1	E287R	Pathogenic	0.992
SLC26A4	O43511-1.1	E287S	Pathogenic	0.993
SLC26A4	O43511-1.1	E287T	Pathogenic	0.998
SLC26A4	O43511-1.1	E287V	Pathogenic	0.999
SLC26A4	O43511-1.1	E287W	Pathogenic	0.995
SLC26A4	O43511-1.1	E287Y	Pathogenic	0.998
SLC26A4	O43511-1.1	L288A	Neutral	0.052
SLC26A4	O43511-1.1	L288C	Neutral	0.145
SLC26A4	O43511-1.1	L288D	Neutral	0.466
SLC26A4	O43511-1.1	L288E	Pathogenic	0.508
SLC26A4	O43511-1.1	L288F	Neutral	0.266
SLC26A4	O43511-1.1	L288G	Neutral	0.144
SLC26A4	O43511-1.1	L288H	Pathogenic	0.676
SLC26A4	O43511-1.1	L288I	Neutral	0.128
SLC26A4	O43511-1.1	L288K	Neutral	0.349
SLC26A4	O43511-1.1	L288M	Neutral	0.113
SLC26A4	O43511-1.1	L288N	Neutral	0.368
SLC26A4	O43511-1.1	L288P	Neutral	0.425
SLC26A4	O43511-1.1	L288Q	Neutral	0.43
SLC26A4	O43511-1.1	L288R	Neutral	0.229
SLC26A4	O43511-1.1	L288S	Neutral	0.113
SLC26A4	O43511-1.1	L288T	Neutral	0.149
SLC26A4	O43511-1.1	L288V	Neutral	0.097
SLC26A4	O43511-1.1	L288W	Neutral	0.257
SLC26A4	O43511-1.1	L288Y	Neutral	0.302
SLC26A4	O43511-1.1	N289A	Pathogenic	0.999
SLC26A4	O43511-1.1	N289C	Pathogenic	1.0
SLC26A4	O43511-1.1	N289D	Pathogenic	0.998
SLC26A4	O43511-1.1	N289E	Pathogenic	0.999
SLC26A4	O43511-1.1	N289F	Pathogenic	0.999
SLC26A4	O43511-1.1	N289G	Pathogenic	0.993
SLC26A4	O43511-1.1	N289H	Pathogenic	0.995
SLC26A4	O43511-1.1	N289I	Pathogenic	0.999
SLC26A4	O43511-1.1	N289K	Pathogenic	0.995
SLC26A4	O43511-1.1	N289L	Pathogenic	0.999
SLC26A4	O43511-1.1	N289M	Pathogenic	0.999
SLC26A4	O43511-1.1	N289P	Pathogenic	1.0
SLC26A4	O43511-1.1	N289Q	Pathogenic	0.998
SLC26A4	O43511-1.1	N289R	Pathogenic	0.992
SLC26A4	O43511-1.1	N289S	Pathogenic	0.995
SLC26A4	O43511-1.1	N289T	Pathogenic	0.999
SLC26A4	O43511-1.1	N289V	Pathogenic	1.0
SLC26A4	O43511-1.1	N289W	Pathogenic	0.997
SLC26A4	O43511-1.1	N289Y	Pathogenic	0.998
SLC26A4	O43511-1.1	D290A	Pathogenic	0.95
SLC26A4	O43511-1.1	D290C	Pathogenic	0.986
SLC26A4	O43511-1.1	D290E	Pathogenic	0.688
SLC26A4	O43511-1.1	D290F	Pathogenic	0.897
SLC26A4	O43511-1.1	D290G	Pathogenic	0.819
SLC26A4	O43511-1.1	D290H	Pathogenic	0.898
SLC26A4	O43511-1.1	D290I	Pathogenic	0.935
SLC26A4	O43511-1.1	D290K	Pathogenic	0.842
SLC26A4	O43511-1.1	D290L	Pathogenic	0.968
SLC26A4	O43511-1.1	D290M	Pathogenic	0.947
SLC26A4	O43511-1.1	D290N	Pathogenic	0.887
SLC26A4	O43511-1.1	D290P	Pathogenic	0.958
SLC26A4	O43511-1.1	D290Q	Pathogenic	0.858
SLC26A4	O43511-1.1	D290R	Pathogenic	0.856
SLC26A4	O43511-1.1	D290S	Pathogenic	0.876
SLC26A4	O43511-1.1	D290T	Pathogenic	0.963
SLC26A4	O43511-1.1	D290V	Pathogenic	0.977
SLC26A4	O43511-1.1	D290W	Pathogenic	0.806
SLC26A4	O43511-1.1	D290Y	Pathogenic	0.902
SLC26A4	O43511-1.1	R291A	Pathogenic	0.967
SLC26A4	O43511-1.1	R291C	Pathogenic	0.995
SLC26A4	O43511-1.1	R291D	Pathogenic	0.996
SLC26A4	O43511-1.1	R291E	Pathogenic	0.993
SLC26A4	O43511-1.1	R291F	Pathogenic	0.999
SLC26A4	O43511-1.1	R291G	Pathogenic	0.965
SLC26A4	O43511-1.1	R291H	Pathogenic	0.994
SLC26A4	O43511-1.1	R291I	Pathogenic	0.999
SLC26A4	O43511-1.1	R291K	Pathogenic	0.992
SLC26A4	O43511-1.1	R291L	Pathogenic	0.998
SLC26A4	O43511-1.1	R291M	Pathogenic	0.996
SLC26A4	O43511-1.1	R291N	Pathogenic	0.987
SLC26A4	O43511-1.1	R291P	Pathogenic	0.993
SLC26A4	O43511-1.1	R291Q	Pathogenic	0.987
SLC26A4	O43511-1.1	R291S	Pathogenic	0.977
SLC26A4	O43511-1.1	R291T	Pathogenic	0.99
SLC26A4	O43511-1.1	R291V	Pathogenic	0.998
SLC26A4	O43511-1.1	R291W	Pathogenic	0.999
SLC26A4	O43511-1.1	R291Y	Pathogenic	0.999
SLC26A4	O43511-1.1	F292A	Pathogenic	0.807
SLC26A4	O43511-1.1	F292C	Pathogenic	0.928
SLC26A4	O43511-1.1	F292D	Pathogenic	0.943
SLC26A4	O43511-1.1	F292E	Pathogenic	0.975
SLC26A4	O43511-1.1	F292G	Pathogenic	0.76
SLC26A4	O43511-1.1	F292H	Pathogenic	0.951
SLC26A4	O43511-1.1	F292I	Pathogenic	0.96
SLC26A4	O43511-1.1	F292K	Pathogenic	0.991
SLC26A4	O43511-1.1	F292L	Pathogenic	0.959
SLC26A4	O43511-1.1	F292M	Pathogenic	0.951
SLC26A4	O43511-1.1	F292N	Pathogenic	0.956
SLC26A4	O43511-1.1	F292P	Pathogenic	0.982
SLC26A4	O43511-1.1	F292Q	Pathogenic	0.983
SLC26A4	O43511-1.1	F292R	Pathogenic	0.984
SLC26A4	O43511-1.1	F292S	Pathogenic	0.828
SLC26A4	O43511-1.1	F292T	Pathogenic	0.93
SLC26A4	O43511-1.1	F292V	Pathogenic	0.943
SLC26A4	O43511-1.1	F292W	Pathogenic	0.823
SLC26A4	O43511-1.1	F292Y	Pathogenic	0.73
SLC26A4	O43511-1.1	R293A	Neutral	0.168
SLC26A4	O43511-1.1	R293C	Pathogenic	0.597
SLC26A4	O43511-1.1	R293D	Pathogenic	0.645
SLC26A4	O43511-1.1	R293E	Neutral	0.491
SLC26A4	O43511-1.1	R293F	Pathogenic	0.909
SLC26A4	O43511-1.1	R293G	Neutral	0.163
SLC26A4	O43511-1.1	R293H	Pathogenic	0.519
SLC26A4	O43511-1.1	R293I	Pathogenic	0.857
SLC26A4	O43511-1.1	R293K	Neutral	0.47
SLC26A4	O43511-1.1	R293L	Pathogenic	0.757
SLC26A4	O43511-1.1	R293M	Pathogenic	0.65
SLC26A4	O43511-1.1	R293N	Neutral	0.346
SLC26A4	O43511-1.1	R293P	Neutral	0.495
SLC26A4	O43511-1.1	R293Q	Neutral	0.339
SLC26A4	O43511-1.1	R293S	Neutral	0.232
SLC26A4	O43511-1.1	R293T	Neutral	0.4
SLC26A4	O43511-1.1	R293V	Pathogenic	0.762
SLC26A4	O43511-1.1	R293W	Pathogenic	0.884
SLC26A4	O43511-1.1	R293Y	Pathogenic	0.899
SLC26A4	O43511-1.1	H294A	Pathogenic	0.885
SLC26A4	O43511-1.1	H294C	Pathogenic	0.966
SLC26A4	O43511-1.1	H294D	Pathogenic	0.895
SLC26A4	O43511-1.1	H294E	Pathogenic	0.91
SLC26A4	O43511-1.1	H294F	Pathogenic	0.909
SLC26A4	O43511-1.1	H294G	Pathogenic	0.768
SLC26A4	O43511-1.1	H294I	Pathogenic	0.985
SLC26A4	O43511-1.1	H294K	Pathogenic	0.925
SLC26A4	O43511-1.1	H294L	Pathogenic	0.986
SLC26A4	O43511-1.1	H294M	Pathogenic	0.976
SLC26A4	O43511-1.1	H294N	Pathogenic	0.739
SLC26A4	O43511-1.1	H294P	Pathogenic	0.949
SLC26A4	O43511-1.1	H294Q	Pathogenic	0.937
SLC26A4	O43511-1.1	H294R	Pathogenic	0.772
SLC26A4	O43511-1.1	H294S	Pathogenic	0.834
SLC26A4	O43511-1.1	H294T	Pathogenic	0.962
SLC26A4	O43511-1.1	H294V	Pathogenic	0.984
SLC26A4	O43511-1.1	H294W	Pathogenic	0.826
SLC26A4	O43511-1.1	H294Y	Pathogenic	0.565
SLC26A4	O43511-1.1	K295A	Pathogenic	0.945
SLC26A4	O43511-1.1	K295C	Pathogenic	0.992
SLC26A4	O43511-1.1	K295D	Pathogenic	0.987
SLC26A4	O43511-1.1	K295E	Pathogenic	0.976
SLC26A4	O43511-1.1	K295F	Pathogenic	0.999
SLC26A4	O43511-1.1	K295G	Pathogenic	0.943
SLC26A4	O43511-1.1	K295H	Pathogenic	0.995
SLC26A4	O43511-1.1	K295I	Pathogenic	0.998
SLC26A4	O43511-1.1	K295L	Pathogenic	0.996
SLC26A4	O43511-1.1	K295M	Pathogenic	0.994
SLC26A4	O43511-1.1	K295N	Pathogenic	0.978
SLC26A4	O43511-1.1	K295P	Pathogenic	0.976
SLC26A4	O43511-1.1	K295Q	Pathogenic	0.978
SLC26A4	O43511-1.1	K295R	Pathogenic	0.976
SLC26A4	O43511-1.1	K295S	Pathogenic	0.927
SLC26A4	O43511-1.1	K295T	Pathogenic	0.983
SLC26A4	O43511-1.1	K295V	Pathogenic	0.993
SLC26A4	O43511-1.1	K295W	Pathogenic	0.995
SLC26A4	O43511-1.1	K295Y	Pathogenic	0.998
SLC26A4	O43511-1.1	I296A	Neutral	0.291
SLC26A4	O43511-1.1	I296C	Pathogenic	0.556
SLC26A4	O43511-1.1	I296D	Pathogenic	0.764
SLC26A4	O43511-1.1	I296E	Pathogenic	0.884
SLC26A4	O43511-1.1	I296F	Pathogenic	0.742
SLC26A4	O43511-1.1	I296G	Pathogenic	0.556
SLC26A4	O43511-1.1	I296H	Pathogenic	0.939
SLC26A4	O43511-1.1	I296K	Pathogenic	0.889
SLC26A4	O43511-1.1	I296L	Pathogenic	0.531
SLC26A4	O43511-1.1	I296M	Pathogenic	0.655
SLC26A4	O43511-1.1	I296N	Pathogenic	0.812
SLC26A4	O43511-1.1	I296P	Pathogenic	0.846
SLC26A4	O43511-1.1	I296Q	Pathogenic	0.919
SLC26A4	O43511-1.1	I296R	Pathogenic	0.816
SLC26A4	O43511-1.1	I296S	Neutral	0.486
SLC26A4	O43511-1.1	I296T	Pathogenic	0.565
SLC26A4	O43511-1.1	I296V	Neutral	0.166
SLC26A4	O43511-1.1	I296W	Pathogenic	0.848
SLC26A4	O43511-1.1	I296Y	Pathogenic	0.762
SLC26A4	O43511-1.1	P297A	Pathogenic	0.996
SLC26A4	O43511-1.1	P297C	Pathogenic	1.0
SLC26A4	O43511-1.1	P297D	Pathogenic	0.998
SLC26A4	O43511-1.1	P297E	Pathogenic	0.995
SLC26A4	O43511-1.1	P297F	Pathogenic	0.998
SLC26A4	O43511-1.1	P297G	Pathogenic	0.994
SLC26A4	O43511-1.1	P297H	Pathogenic	0.997
SLC26A4	O43511-1.1	P297I	Pathogenic	0.998
SLC26A4	O43511-1.1	P297K	Pathogenic	0.981
SLC26A4	O43511-1.1	P297L	Pathogenic	0.998
SLC26A4	O43511-1.1	P297M	Pathogenic	0.996
SLC26A4	O43511-1.1	P297N	Pathogenic	0.999
SLC26A4	O43511-1.1	P297Q	Pathogenic	0.995
SLC26A4	O43511-1.1	P297R	Pathogenic	0.983
SLC26A4	O43511-1.1	P297S	Pathogenic	0.996
SLC26A4	O43511-1.1	P297T	Pathogenic	0.998
SLC26A4	O43511-1.1	P297V	Pathogenic	0.998
SLC26A4	O43511-1.1	P297W	Pathogenic	0.992
SLC26A4	O43511-1.1	P297Y	Pathogenic	0.996
SLC26A4	O43511-1.1	V298A	Neutral	0.468
SLC26A4	O43511-1.1	V298C	Pathogenic	0.844
SLC26A4	O43511-1.1	V298D	Pathogenic	0.933
SLC26A4	O43511-1.1	V298E	Pathogenic	0.92
SLC26A4	O43511-1.1	V298F	Pathogenic	0.743
SLC26A4	O43511-1.1	V298G	Pathogenic	0.729
SLC26A4	O43511-1.1	V298H	Pathogenic	0.954
SLC26A4	O43511-1.1	V298I	Neutral	0.225
SLC26A4	O43511-1.1	V298K	Pathogenic	0.755
SLC26A4	O43511-1.1	V298L	Pathogenic	0.549
SLC26A4	O43511-1.1	V298M	Pathogenic	0.593
SLC26A4	O43511-1.1	V298N	Pathogenic	0.949
SLC26A4	O43511-1.1	V298P	Pathogenic	0.922
SLC26A4	O43511-1.1	V298Q	Pathogenic	0.915
SLC26A4	O43511-1.1	V298R	Pathogenic	0.774
SLC26A4	O43511-1.1	V298S	Pathogenic	0.803
SLC26A4	O43511-1.1	V298T	Pathogenic	0.736
SLC26A4	O43511-1.1	V298W	Pathogenic	0.734
SLC26A4	O43511-1.1	V298Y	Pathogenic	0.713
SLC26A4	O43511-1.1	P299A	Pathogenic	0.998
SLC26A4	O43511-1.1	P299C	Pathogenic	1.0
SLC26A4	O43511-1.1	P299D	Pathogenic	0.999
SLC26A4	O43511-1.1	P299E	Pathogenic	0.997
SLC26A4	O43511-1.1	P299F	Pathogenic	0.999
SLC26A4	O43511-1.1	P299G	Pathogenic	0.997
SLC26A4	O43511-1.1	P299H	Pathogenic	0.999
SLC26A4	O43511-1.1	P299I	Pathogenic	0.999
SLC26A4	O43511-1.1	P299K	Pathogenic	0.99
SLC26A4	O43511-1.1	P299L	Pathogenic	0.999
SLC26A4	O43511-1.1	P299M	Pathogenic	0.998
SLC26A4	O43511-1.1	P299N	Pathogenic	0.999
SLC26A4	O43511-1.1	P299Q	Pathogenic	0.997
SLC26A4	O43511-1.1	P299R	Pathogenic	0.991
SLC26A4	O43511-1.1	P299S	Pathogenic	0.998
SLC26A4	O43511-1.1	P299T	Pathogenic	0.999
SLC26A4	O43511-1.1	P299V	Pathogenic	0.999
SLC26A4	O43511-1.1	P299W	Pathogenic	0.996
SLC26A4	O43511-1.1	P299Y	Pathogenic	0.998
SLC26A4	O43511-1.1	I300A	Pathogenic	0.921
SLC26A4	O43511-1.1	I300C	Pathogenic	0.973
SLC26A4	O43511-1.1	I300D	Pathogenic	0.989
SLC26A4	O43511-1.1	I300E	Pathogenic	0.995
SLC26A4	O43511-1.1	I300F	Pathogenic	0.988
SLC26A4	O43511-1.1	I300G	Pathogenic	0.973
SLC26A4	O43511-1.1	I300H	Pathogenic	0.998
SLC26A4	O43511-1.1	I300K	Pathogenic	0.996
SLC26A4	O43511-1.1	I300L	Pathogenic	0.97
SLC26A4	O43511-1.1	I300M	Pathogenic	0.982
SLC26A4	O43511-1.1	I300N	Pathogenic	0.992
SLC26A4	O43511-1.1	I300P	Pathogenic	0.994
SLC26A4	O43511-1.1	I300Q	Pathogenic	0.997
SLC26A4	O43511-1.1	I300R	Pathogenic	0.992
SLC26A4	O43511-1.1	I300S	Pathogenic	0.964
SLC26A4	O43511-1.1	I300T	Pathogenic	0.974
SLC26A4	O43511-1.1	I300V	Pathogenic	0.85
SLC26A4	O43511-1.1	I300W	Pathogenic	0.994
SLC26A4	O43511-1.1	I300Y	Pathogenic	0.989
SLC26A4	O43511-1.1	P301A	Pathogenic	0.998
SLC26A4	O43511-1.1	P301C	Pathogenic	1.0
SLC26A4	O43511-1.1	P301D	Pathogenic	0.999
SLC26A4	O43511-1.1	P301E	Pathogenic	0.997
SLC26A4	O43511-1.1	P301F	Pathogenic	0.999
SLC26A4	O43511-1.1	P301G	Pathogenic	0.997
SLC26A4	O43511-1.1	P301H	Pathogenic	0.999
SLC26A4	O43511-1.1	P301I	Pathogenic	0.999
SLC26A4	O43511-1.1	P301K	Pathogenic	0.99
SLC26A4	O43511-1.1	P301L	Pathogenic	0.999
SLC26A4	O43511-1.1	P301M	Pathogenic	0.998
SLC26A4	O43511-1.1	P301N	Pathogenic	0.999
SLC26A4	O43511-1.1	P301Q	Pathogenic	0.997
SLC26A4	O43511-1.1	P301R	Pathogenic	0.991
SLC26A4	O43511-1.1	P301S	Pathogenic	0.998
SLC26A4	O43511-1.1	P301T	Pathogenic	0.999
SLC26A4	O43511-1.1	P301V	Pathogenic	0.999
SLC26A4	O43511-1.1	P301W	Pathogenic	0.996
SLC26A4	O43511-1.1	P301Y	Pathogenic	0.998
SLC26A4	O43511-1.1	I302A	Pathogenic	0.835
SLC26A4	O43511-1.1	I302C	Pathogenic	0.939
SLC26A4	O43511-1.1	I302D	Pathogenic	0.975
SLC26A4	O43511-1.1	I302E	Pathogenic	0.99
SLC26A4	O43511-1.1	I302F	Pathogenic	0.973
SLC26A4	O43511-1.1	I302G	Pathogenic	0.939
SLC26A4	O43511-1.1	I302H	Pathogenic	0.995
SLC26A4	O43511-1.1	I302K	Pathogenic	0.99
SLC26A4	O43511-1.1	I302L	Pathogenic	0.933
SLC26A4	O43511-1.1	I302M	Pathogenic	0.959
SLC26A4	O43511-1.1	I302N	Pathogenic	0.982
SLC26A4	O43511-1.1	I302P	Pathogenic	0.985
SLC26A4	O43511-1.1	I302Q	Pathogenic	0.993
SLC26A4	O43511-1.1	I302R	Pathogenic	0.982
SLC26A4	O43511-1.1	I302S	Pathogenic	0.921
SLC26A4	O43511-1.1	I302T	Pathogenic	0.941
SLC26A4	O43511-1.1	I302V	Pathogenic	0.71
SLC26A4	O43511-1.1	I302W	Pathogenic	0.986
SLC26A4	O43511-1.1	I302Y	Pathogenic	0.975
SLC26A4	O43511-1.1	E303A	Pathogenic	0.993
SLC26A4	O43511-1.1	E303C	Pathogenic	1.0
SLC26A4	O43511-1.1	E303D	Pathogenic	0.986
SLC26A4	O43511-1.1	E303F	Pathogenic	0.999
SLC26A4	O43511-1.1	E303G	Pathogenic	0.993
SLC26A4	O43511-1.1	E303H	Pathogenic	0.997
SLC26A4	O43511-1.1	E303I	Pathogenic	0.999
SLC26A4	O43511-1.1	E303K	Pathogenic	0.989
SLC26A4	O43511-1.1	E303L	Pathogenic	0.999
SLC26A4	O43511-1.1	E303M	Pathogenic	0.999
SLC26A4	O43511-1.1	E303N	Pathogenic	0.997
SLC26A4	O43511-1.1	E303P	Pathogenic	0.997
SLC26A4	O43511-1.1	E303Q	Pathogenic	0.991
SLC26A4	O43511-1.1	E303R	Pathogenic	0.99
SLC26A4	O43511-1.1	E303S	Pathogenic	0.991
SLC26A4	O43511-1.1	E303T	Pathogenic	0.998
SLC26A4	O43511-1.1	E303V	Pathogenic	0.999
SLC26A4	O43511-1.1	E303W	Pathogenic	0.994
SLC26A4	O43511-1.1	E303Y	Pathogenic	0.997
SLC26A4	O43511-1.1	V304A	Neutral	0.26
SLC26A4	O43511-1.1	V304C	Pathogenic	0.684
SLC26A4	O43511-1.1	V304D	Pathogenic	0.848
SLC26A4	O43511-1.1	V304E	Pathogenic	0.821
SLC26A4	O43511-1.1	V304F	Pathogenic	0.536
SLC26A4	O43511-1.1	V304G	Pathogenic	0.518
SLC26A4	O43511-1.1	V304H	Pathogenic	0.892
SLC26A4	O43511-1.1	V304I	Neutral	0.104
SLC26A4	O43511-1.1	V304K	Pathogenic	0.553
SLC26A4	O43511-1.1	V304L	Neutral	0.327
SLC26A4	O43511-1.1	V304M	Neutral	0.368
SLC26A4	O43511-1.1	V304N	Pathogenic	0.881
SLC26A4	O43511-1.1	V304P	Pathogenic	0.824
SLC26A4	O43511-1.1	V304Q	Pathogenic	0.811
SLC26A4	O43511-1.1	V304R	Pathogenic	0.578
SLC26A4	O43511-1.1	V304S	Pathogenic	0.62
SLC26A4	O43511-1.1	V304T	Pathogenic	0.527
SLC26A4	O43511-1.1	V304W	Pathogenic	0.524
SLC26A4	O43511-1.1	V304Y	Neutral	0.499
SLC26A4	O43511-1.1	I305A	Pathogenic	0.739
SLC26A4	O43511-1.1	I305C	Pathogenic	0.896
SLC26A4	O43511-1.1	I305D	Pathogenic	0.957
SLC26A4	O43511-1.1	I305E	Pathogenic	0.981
SLC26A4	O43511-1.1	I305F	Pathogenic	0.952
SLC26A4	O43511-1.1	I305G	Pathogenic	0.896
SLC26A4	O43511-1.1	I305H	Pathogenic	0.991
SLC26A4	O43511-1.1	I305K	Pathogenic	0.982
SLC26A4	O43511-1.1	I305L	Pathogenic	0.887
SLC26A4	O43511-1.1	I305M	Pathogenic	0.929
SLC26A4	O43511-1.1	I305N	Pathogenic	0.968
SLC26A4	O43511-1.1	I305P	Pathogenic	0.974
SLC26A4	O43511-1.1	I305Q	Pathogenic	0.987
SLC26A4	O43511-1.1	I305R	Pathogenic	0.968
SLC26A4	O43511-1.1	I305S	Pathogenic	0.867
SLC26A4	O43511-1.1	I305T	Pathogenic	0.9
SLC26A4	O43511-1.1	I305V	Pathogenic	0.578
SLC26A4	O43511-1.1	I305W	Pathogenic	0.975
SLC26A4	O43511-1.1	I305Y	Pathogenic	0.957
SLC26A4	O43511-1.1	V306A	Pathogenic	0.737
SLC26A4	O43511-1.1	V306C	Pathogenic	0.945
SLC26A4	O43511-1.1	V306D	Pathogenic	0.978
SLC26A4	O43511-1.1	V306E	Pathogenic	0.973
SLC26A4	O43511-1.1	V306F	Pathogenic	0.902
SLC26A4	O43511-1.1	V306G	Pathogenic	0.895
SLC26A4	O43511-1.1	V306H	Pathogenic	0.985
SLC26A4	O43511-1.1	V306I	Neutral	0.48
SLC26A4	O43511-1.1	V306K	Pathogenic	0.908
SLC26A4	O43511-1.1	V306L	Pathogenic	0.795
SLC26A4	O43511-1.1	V306M	Pathogenic	0.823
SLC26A4	O43511-1.1	V306N	Pathogenic	0.983
SLC26A4	O43511-1.1	V306P	Pathogenic	0.974
SLC26A4	O43511-1.1	V306Q	Pathogenic	0.972
SLC26A4	O43511-1.1	V306R	Pathogenic	0.916
SLC26A4	O43511-1.1	V306S	Pathogenic	0.928
SLC26A4	O43511-1.1	V306T	Pathogenic	0.899
SLC26A4	O43511-1.1	V306W	Pathogenic	0.898
SLC26A4	O43511-1.1	V306Y	Pathogenic	0.888
SLC26A4	O43511-1.1	T307A	Pathogenic	0.986
SLC26A4	O43511-1.1	T307C	Pathogenic	0.996
SLC26A4	O43511-1.1	T307D	Pathogenic	0.996
SLC26A4	O43511-1.1	T307E	Pathogenic	0.994
SLC26A4	O43511-1.1	T307F	Pathogenic	0.987
SLC26A4	O43511-1.1	T307G	Pathogenic	0.991
SLC26A4	O43511-1.1	T307H	Pathogenic	0.996
SLC26A4	O43511-1.1	T307I	Pathogenic	0.984
SLC26A4	O43511-1.1	T307K	Pathogenic	0.977
SLC26A4	O43511-1.1	T307L	Pathogenic	0.985
SLC26A4	O43511-1.1	T307M	Pathogenic	0.987
SLC26A4	O43511-1.1	T307N	Pathogenic	0.993
SLC26A4	O43511-1.1	T307P	Pathogenic	0.997
SLC26A4	O43511-1.1	T307Q	Pathogenic	0.993
SLC26A4	O43511-1.1	T307R	Pathogenic	0.959
SLC26A4	O43511-1.1	T307S	Pathogenic	0.976
SLC26A4	O43511-1.1	T307V	Pathogenic	0.989
SLC26A4	O43511-1.1	T307W	Pathogenic	0.947
SLC26A4	O43511-1.1	T307Y	Pathogenic	0.988
SLC26A4	O43511-1.1	I308A	Neutral	0.409
SLC26A4	O43511-1.1	I308C	Pathogenic	0.679
SLC26A4	O43511-1.1	I308D	Pathogenic	0.845
SLC26A4	O43511-1.1	I308E	Pathogenic	0.928
SLC26A4	O43511-1.1	I308F	Pathogenic	0.829
SLC26A4	O43511-1.1	I308G	Pathogenic	0.679
SLC26A4	O43511-1.1	I308H	Pathogenic	0.963
SLC26A4	O43511-1.1	I308K	Pathogenic	0.931
SLC26A4	O43511-1.1	I308L	Pathogenic	0.657
SLC26A4	O43511-1.1	I308M	Pathogenic	0.762
SLC26A4	O43511-1.1	I308N	Pathogenic	0.879
SLC26A4	O43511-1.1	I308P	Pathogenic	0.902
SLC26A4	O43511-1.1	I308Q	Pathogenic	0.95
SLC26A4	O43511-1.1	I308R	Pathogenic	0.882
SLC26A4	O43511-1.1	I308S	Pathogenic	0.615
SLC26A4	O43511-1.1	I308T	Pathogenic	0.687
SLC26A4	O43511-1.1	I308V	Neutral	0.251
SLC26A4	O43511-1.1	I308W	Pathogenic	0.904
SLC26A4	O43511-1.1	I308Y	Pathogenic	0.844
SLC26A4	O43511-1.1	I309A	Neutral	0.279
SLC26A4	O43511-1.1	I309C	Pathogenic	0.542
SLC26A4	O43511-1.1	I309D	Pathogenic	0.753
SLC26A4	O43511-1.1	I309E	Pathogenic	0.878
SLC26A4	O43511-1.1	I309F	Pathogenic	0.731
SLC26A4	O43511-1.1	I309G	Pathogenic	0.541
SLC26A4	O43511-1.1	I309H	Pathogenic	0.936
SLC26A4	O43511-1.1	I309K	Pathogenic	0.883
SLC26A4	O43511-1.1	I309L	Pathogenic	0.517
SLC26A4	O43511-1.1	I309M	Pathogenic	0.642
SLC26A4	O43511-1.1	I309N	Pathogenic	0.803
SLC26A4	O43511-1.1	I309P	Pathogenic	0.838
SLC26A4	O43511-1.1	I309Q	Pathogenic	0.914
SLC26A4	O43511-1.1	I309R	Pathogenic	0.807
SLC26A4	O43511-1.1	I309S	Neutral	0.471
SLC26A4	O43511-1.1	I309T	Pathogenic	0.551
SLC26A4	O43511-1.1	I309V	Neutral	0.158
SLC26A4	O43511-1.1	I309W	Pathogenic	0.84
SLC26A4	O43511-1.1	I309Y	Pathogenic	0.751
SLC26A4	O43511-1.1	A310C	Pathogenic	0.968
SLC26A4	O43511-1.1	A310D	Pathogenic	0.988
SLC26A4	O43511-1.1	A310E	Pathogenic	0.951
SLC26A4	O43511-1.1	A310F	Pathogenic	0.908
SLC26A4	O43511-1.1	A310G	Pathogenic	0.972
SLC26A4	O43511-1.1	A310H	Pathogenic	0.972
SLC26A4	O43511-1.1	A310I	Pathogenic	0.889
SLC26A4	O43511-1.1	A310K	Pathogenic	0.84
SLC26A4	O43511-1.1	A310L	Pathogenic	0.893
SLC26A4	O43511-1.1	A310M	Pathogenic	0.909
SLC26A4	O43511-1.1	A310N	Pathogenic	0.986
SLC26A4	O43511-1.1	A310P	Pathogenic	0.983
SLC26A4	O43511-1.1	A310Q	Pathogenic	0.948
SLC26A4	O43511-1.1	A310R	Pathogenic	0.744
SLC26A4	O43511-1.1	A310S	Pathogenic	0.969
SLC26A4	O43511-1.1	A310T	Pathogenic	0.966
SLC26A4	O43511-1.1	A310V	Pathogenic	0.922
SLC26A4	O43511-1.1	A310W	Pathogenic	0.824
SLC26A4	O43511-1.1	A310Y	Pathogenic	0.912
SLC26A4	O43511-1.1	T311A	Pathogenic	0.909
SLC26A4	O43511-1.1	T311C	Pathogenic	0.973
SLC26A4	O43511-1.1	T311D	Pathogenic	0.976
SLC26A4	O43511-1.1	T311E	Pathogenic	0.958
SLC26A4	O43511-1.1	T311F	Pathogenic	0.917
SLC26A4	O43511-1.1	T311G	Pathogenic	0.941
SLC26A4	O43511-1.1	T311H	Pathogenic	0.976
SLC26A4	O43511-1.1	T311I	Pathogenic	0.9
SLC26A4	O43511-1.1	T311K	Pathogenic	0.861
SLC26A4	O43511-1.1	T311L	Pathogenic	0.904
SLC26A4	O43511-1.1	T311M	Pathogenic	0.918
SLC26A4	O43511-1.1	T311N	Pathogenic	0.954
SLC26A4	O43511-1.1	T311P	Pathogenic	0.98
SLC26A4	O43511-1.1	T311Q	Pathogenic	0.955
SLC26A4	O43511-1.1	T311R	Pathogenic	0.773
SLC26A4	O43511-1.1	T311S	Pathogenic	0.856
SLC26A4	O43511-1.1	T311V	Pathogenic	0.93
SLC26A4	O43511-1.1	T311W	Pathogenic	0.724
SLC26A4	O43511-1.1	T311Y	Pathogenic	0.921
SLC26A4	O43511-1.1	A312C	Neutral	0.372
SLC26A4	O43511-1.1	A312D	Pathogenic	0.62
SLC26A4	O43511-1.1	A312E	Neutral	0.275
SLC26A4	O43511-1.1	A312F	Neutral	0.161
SLC26A4	O43511-1.1	A312G	Neutral	0.406
SLC26A4	O43511-1.1	A312H	Neutral	0.406
SLC26A4	O43511-1.1	A312I	Neutral	0.135
SLC26A4	O43511-1.1	A312K	Neutral	0.093
SLC26A4	O43511-1.1	A312L	Neutral	0.14
SLC26A4	O43511-1.1	A312M	Neutral	0.163
SLC26A4	O43511-1.1	A312N	Pathogenic	0.582
SLC26A4	O43511-1.1	A312P	Pathogenic	0.524
SLC26A4	O43511-1.1	A312Q	Neutral	0.263
SLC26A4	O43511-1.1	A312R	Neutral	0.054
SLC26A4	O43511-1.1	A312S	Neutral	0.376
SLC26A4	O43511-1.1	A312T	Neutral	0.355
SLC26A4	O43511-1.1	A312V	Neutral	0.187
SLC26A4	O43511-1.1	A312W	Neutral	0.084
SLC26A4	O43511-1.1	A312Y	Neutral	0.168
SLC26A4	O43511-1.1	I313A	Neutral	0.435
SLC26A4	O43511-1.1	I313C	Pathogenic	0.702
SLC26A4	O43511-1.1	I313D	Pathogenic	0.859
SLC26A4	O43511-1.1	I313E	Pathogenic	0.935
SLC26A4	O43511-1.1	I313F	Pathogenic	0.844
SLC26A4	O43511-1.1	I313G	Pathogenic	0.702
SLC26A4	O43511-1.1	I313H	Pathogenic	0.967
SLC26A4	O43511-1.1	I313K	Pathogenic	0.938
SLC26A4	O43511-1.1	I313L	Pathogenic	0.681
SLC26A4	O43511-1.1	I313M	Pathogenic	0.781
SLC26A4	O43511-1.1	I313N	Pathogenic	0.89
SLC26A4	O43511-1.1	I313P	Pathogenic	0.911
SLC26A4	O43511-1.1	I313Q	Pathogenic	0.955
SLC26A4	O43511-1.1	I313R	Pathogenic	0.893
SLC26A4	O43511-1.1	I313S	Pathogenic	0.64
SLC26A4	O43511-1.1	I313T	Pathogenic	0.71
SLC26A4	O43511-1.1	I313V	Neutral	0.272
SLC26A4	O43511-1.1	I313W	Pathogenic	0.913
SLC26A4	O43511-1.1	I313Y	Pathogenic	0.858
SLC26A4	O43511-1.1	S314A	Pathogenic	0.99
SLC26A4	O43511-1.1	S314C	Pathogenic	0.996
SLC26A4	O43511-1.1	S314D	Pathogenic	0.99
SLC26A4	O43511-1.1	S314E	Pathogenic	0.979
SLC26A4	O43511-1.1	S314F	Pathogenic	0.973
SLC26A4	O43511-1.1	S314G	Pathogenic	0.989
SLC26A4	O43511-1.1	S314H	Pathogenic	0.986
SLC26A4	O43511-1.1	S314I	Pathogenic	0.983
SLC26A4	O43511-1.1	S314K	Pathogenic	0.925
SLC26A4	O43511-1.1	S314L	Pathogenic	0.984
SLC26A4	O43511-1.1	S314M	Pathogenic	0.973
SLC26A4	O43511-1.1	S314N	Pathogenic	0.977
SLC26A4	O43511-1.1	S314P	Pathogenic	0.995
SLC26A4	O43511-1.1	S314Q	Pathogenic	0.977
SLC26A4	O43511-1.1	S314R	Pathogenic	0.932
SLC26A4	O43511-1.1	S314T	Pathogenic	0.981
SLC26A4	O43511-1.1	S314V	Pathogenic	0.994
SLC26A4	O43511-1.1	S314W	Pathogenic	0.944
SLC26A4	O43511-1.1	S314Y	Pathogenic	0.974
SLC26A4	O43511-1.1	Y315A	Pathogenic	0.981
SLC26A4	O43511-1.1	Y315C	Pathogenic	0.993
SLC26A4	O43511-1.1	Y315D	Pathogenic	0.995
SLC26A4	O43511-1.1	Y315E	Pathogenic	0.996
SLC26A4	O43511-1.1	Y315F	Pathogenic	0.969
SLC26A4	O43511-1.1	Y315G	Pathogenic	0.975
SLC26A4	O43511-1.1	Y315H	Pathogenic	0.967
SLC26A4	O43511-1.1	Y315I	Pathogenic	0.997
SLC26A4	O43511-1.1	Y315K	Pathogenic	0.998
SLC26A4	O43511-1.1	Y315L	Pathogenic	0.997
SLC26A4	O43511-1.1	Y315M	Pathogenic	0.997
SLC26A4	O43511-1.1	Y315N	Pathogenic	0.992
SLC26A4	O43511-1.1	Y315P	Pathogenic	0.997
SLC26A4	O43511-1.1	Y315Q	Pathogenic	0.994
SLC26A4	O43511-1.1	Y315R	Pathogenic	0.998
SLC26A4	O43511-1.1	Y315S	Pathogenic	0.983
SLC26A4	O43511-1.1	Y315T	Pathogenic	0.994
SLC26A4	O43511-1.1	Y315V	Pathogenic	0.994
SLC26A4	O43511-1.1	Y315W	Pathogenic	0.962
SLC26A4	O43511-1.1	G316A	Pathogenic	0.817
SLC26A4	O43511-1.1	G316C	Pathogenic	0.922
SLC26A4	O43511-1.1	G316D	Pathogenic	0.718
SLC26A4	O43511-1.1	G316E	Pathogenic	0.705
SLC26A4	O43511-1.1	G316F	Neutral	0.488
SLC26A4	O43511-1.1	G316H	Pathogenic	0.659
SLC26A4	O43511-1.1	G316I	Pathogenic	0.758
SLC26A4	O43511-1.1	G316K	Neutral	0.392
SLC26A4	O43511-1.1	G316L	Pathogenic	0.765
SLC26A4	O43511-1.1	G316M	Pathogenic	0.66
SLC26A4	O43511-1.1	G316N	Pathogenic	0.519
SLC26A4	O43511-1.1	G316P	Pathogenic	0.845
SLC26A4	O43511-1.1	G316Q	Pathogenic	0.691
SLC26A4	O43511-1.1	G316R	Neutral	0.263
SLC26A4	O43511-1.1	G316S	Pathogenic	0.791
SLC26A4	O43511-1.1	G316T	Pathogenic	0.851
SLC26A4	O43511-1.1	G316V	Pathogenic	0.821
SLC26A4	O43511-1.1	G316W	Neutral	0.101
SLC26A4	O43511-1.1	G316Y	Neutral	0.5
SLC26A4	O43511-1.1	A317C	Neutral	0.17
SLC26A4	O43511-1.1	A317D	Neutral	0.361
SLC26A4	O43511-1.1	A317E	Neutral	0.116
SLC26A4	O43511-1.1	A317F	Neutral	0.062
SLC26A4	O43511-1.1	A317G	Neutral	0.191
SLC26A4	O43511-1.1	A317H	Neutral	0.191
SLC26A4	O43511-1.1	A317I	Neutral	0.051
SLC26A4	O43511-1.1	A317K	Neutral	0.034
SLC26A4	O43511-1.1	A317L	Neutral	0.053
SLC26A4	O43511-1.1	A317M	Neutral	0.063
SLC26A4	O43511-1.1	A317N	Neutral	0.325
SLC26A4	O43511-1.1	A317P	Neutral	0.276
SLC26A4	O43511-1.1	A317Q	Neutral	0.11
SLC26A4	O43511-1.1	A317R	Neutral	0.019
SLC26A4	O43511-1.1	A317S	Neutral	0.172
SLC26A4	O43511-1.1	A317T	Neutral	0.16
SLC26A4	O43511-1.1	A317V	Neutral	0.074
SLC26A4	O43511-1.1	A317W	Neutral	0.031
SLC26A4	O43511-1.1	A317Y	Neutral	0.065
SLC26A4	O43511-1.1	N318A	Pathogenic	0.963
SLC26A4	O43511-1.1	N318C	Pathogenic	0.989
SLC26A4	O43511-1.1	N318D	Pathogenic	0.926
SLC26A4	O43511-1.1	N318E	Pathogenic	0.948
SLC26A4	O43511-1.1	N318F	Pathogenic	0.949
SLC26A4	O43511-1.1	N318G	Pathogenic	0.753
SLC26A4	O43511-1.1	N318H	Pathogenic	0.823
SLC26A4	O43511-1.1	N318I	Pathogenic	0.968
SLC26A4	O43511-1.1	N318K	Pathogenic	0.832
SLC26A4	O43511-1.1	N318L	Pathogenic	0.969
SLC26A4	O43511-1.1	N318M	Pathogenic	0.95
SLC26A4	O43511-1.1	N318P	Pathogenic	0.984
SLC26A4	O43511-1.1	N318Q	Pathogenic	0.928
SLC26A4	O43511-1.1	N318R	Pathogenic	0.733
SLC26A4	O43511-1.1	N318S	Pathogenic	0.826
SLC26A4	O43511-1.1	N318T	Pathogenic	0.955
SLC26A4	O43511-1.1	N318V	Pathogenic	0.989
SLC26A4	O43511-1.1	N318W	Pathogenic	0.898
SLC26A4	O43511-1.1	N318Y	Pathogenic	0.907
SLC26A4	O43511-1.1	L319A	Neutral	0.415
SLC26A4	O43511-1.1	L319C	Pathogenic	0.684
SLC26A4	O43511-1.1	L319D	Pathogenic	0.918
SLC26A4	O43511-1.1	L319E	Pathogenic	0.93
SLC26A4	O43511-1.1	L319F	Pathogenic	0.823
SLC26A4	O43511-1.1	L319G	Pathogenic	0.684
SLC26A4	O43511-1.1	L319H	Pathogenic	0.964
SLC26A4	O43511-1.1	L319I	Pathogenic	0.653
SLC26A4	O43511-1.1	L319K	Pathogenic	0.873
SLC26A4	O43511-1.1	L319M	Pathogenic	0.62
SLC26A4	O43511-1.1	L319N	Pathogenic	0.882
SLC26A4	O43511-1.1	L319P	Pathogenic	0.904
SLC26A4	O43511-1.1	L319Q	Pathogenic	0.906
SLC26A4	O43511-1.1	L319R	Pathogenic	0.792
SLC26A4	O43511-1.1	L319S	Pathogenic	0.62
SLC26A4	O43511-1.1	L319T	Pathogenic	0.692
SLC26A4	O43511-1.1	L319V	Pathogenic	0.581
SLC26A4	O43511-1.1	L319W	Pathogenic	0.816
SLC26A4	O43511-1.1	L319Y	Pathogenic	0.847
SLC26A4	O43511-1.1	E320A	Pathogenic	0.818
SLC26A4	O43511-1.1	E320C	Pathogenic	0.985
SLC26A4	O43511-1.1	E320D	Pathogenic	0.692
SLC26A4	O43511-1.1	E320F	Pathogenic	0.955
SLC26A4	O43511-1.1	E320G	Pathogenic	0.812
SLC26A4	O43511-1.1	E320H	Pathogenic	0.914
SLC26A4	O43511-1.1	E320I	Pathogenic	0.972
SLC26A4	O43511-1.1	E320K	Pathogenic	0.743
SLC26A4	O43511-1.1	E320L	Pathogenic	0.973
SLC26A4	O43511-1.1	E320M	Pathogenic	0.955
SLC26A4	O43511-1.1	E320N	Pathogenic	0.922
SLC26A4	O43511-1.1	E320P	Pathogenic	0.916
SLC26A4	O43511-1.1	E320Q	Pathogenic	0.783
SLC26A4	O43511-1.1	E320R	Pathogenic	0.762
SLC26A4	O43511-1.1	E320S	Pathogenic	0.77
SLC26A4	O43511-1.1	E320T	Pathogenic	0.937
SLC26A4	O43511-1.1	E320V	Pathogenic	0.973
SLC26A4	O43511-1.1	E320W	Pathogenic	0.833
SLC26A4	O43511-1.1	E320Y	Pathogenic	0.917
SLC26A4	O43511-1.1	K321A	Neutral	0.051
SLC26A4	O43511-1.1	K321C	Neutral	0.283
SLC26A4	O43511-1.1	K321D	Neutral	0.194
SLC26A4	O43511-1.1	K321E	Neutral	0.114
SLC26A4	O43511-1.1	K321F	Pathogenic	0.726
SLC26A4	O43511-1.1	K321G	Neutral	0.049
SLC26A4	O43511-1.1	K321H	Neutral	0.366
SLC26A4	O43511-1.1	K321I	Pathogenic	0.616
SLC26A4	O43511-1.1	K321L	Neutral	0.453
SLC26A4	O43511-1.1	K321M	Neutral	0.331
SLC26A4	O43511-1.1	K321N	Neutral	0.124
SLC26A4	O43511-1.1	K321P	Neutral	0.115
SLC26A4	O43511-1.1	K321Q	Neutral	0.12
SLC26A4	O43511-1.1	K321R	Neutral	0.115
SLC26A4	O43511-1.1	K321S	Neutral	0.039
SLC26A4	O43511-1.1	K321T	Neutral	0.151
SLC26A4	O43511-1.1	K321V	Neutral	0.298
SLC26A4	O43511-1.1	K321W	Neutral	0.385
SLC26A4	O43511-1.1	K321Y	Pathogenic	0.58
SLC26A4	O43511-1.1	N322A	Pathogenic	0.618
SLC26A4	O43511-1.1	N322C	Pathogenic	0.855
SLC26A4	O43511-1.1	N322D	Neutral	0.439
SLC26A4	O43511-1.1	N322E	Pathogenic	0.536
SLC26A4	O43511-1.1	N322F	Pathogenic	0.539
SLC26A4	O43511-1.1	N322G	Neutral	0.161
SLC26A4	O43511-1.1	N322H	Neutral	0.226
SLC26A4	O43511-1.1	N322I	Pathogenic	0.656
SLC26A4	O43511-1.1	N322K	Neutral	0.238
SLC26A4	O43511-1.1	N322L	Pathogenic	0.665
SLC26A4	O43511-1.1	N322M	Pathogenic	0.542
SLC26A4	O43511-1.1	N322P	Pathogenic	0.796
SLC26A4	O43511-1.1	N322Q	Neutral	0.447
SLC26A4	O43511-1.1	N322R	Neutral	0.147
SLC26A4	O43511-1.1	N322S	Neutral	0.23
SLC26A4	O43511-1.1	N322T	Pathogenic	0.569
SLC26A4	O43511-1.1	N322V	Pathogenic	0.849
SLC26A4	O43511-1.1	N322W	Neutral	0.357
SLC26A4	O43511-1.1	N322Y	Neutral	0.379
SLC26A4	O43511-1.1	Y323A	Pathogenic	0.921
SLC26A4	O43511-1.1	Y323C	Pathogenic	0.972
SLC26A4	O43511-1.1	Y323D	Pathogenic	0.979
SLC26A4	O43511-1.1	Y323E	Pathogenic	0.982
SLC26A4	O43511-1.1	Y323F	Pathogenic	0.878
SLC26A4	O43511-1.1	Y323G	Pathogenic	0.899
SLC26A4	O43511-1.1	Y323H	Pathogenic	0.871
SLC26A4	O43511-1.1	Y323I	Pathogenic	0.986
SLC26A4	O43511-1.1	Y323K	Pathogenic	0.994
SLC26A4	O43511-1.1	Y323L	Pathogenic	0.987
SLC26A4	O43511-1.1	Y323M	Pathogenic	0.989
SLC26A4	O43511-1.1	Y323N	Pathogenic	0.968
SLC26A4	O43511-1.1	Y323P	Pathogenic	0.987
SLC26A4	O43511-1.1	Y323Q	Pathogenic	0.975
SLC26A4	O43511-1.1	Y323R	Pathogenic	0.993
SLC26A4	O43511-1.1	Y323S	Pathogenic	0.931
SLC26A4	O43511-1.1	Y323T	Pathogenic	0.974
SLC26A4	O43511-1.1	Y323V	Pathogenic	0.974
SLC26A4	O43511-1.1	Y323W	Pathogenic	0.855
SLC26A4	O43511-1.1	N324A	Pathogenic	0.971
SLC26A4	O43511-1.1	N324C	Pathogenic	0.992
SLC26A4	O43511-1.1	N324D	Pathogenic	0.942
SLC26A4	O43511-1.1	N324E	Pathogenic	0.96
SLC26A4	O43511-1.1	N324F	Pathogenic	0.961
SLC26A4	O43511-1.1	N324G	Pathogenic	0.799
SLC26A4	O43511-1.1	N324H	Pathogenic	0.859
SLC26A4	O43511-1.1	N324I	Pathogenic	0.975
SLC26A4	O43511-1.1	N324K	Pathogenic	0.867
SLC26A4	O43511-1.1	N324L	Pathogenic	0.976
SLC26A4	O43511-1.1	N324M	Pathogenic	0.961
SLC26A4	O43511-1.1	N324P	Pathogenic	0.988
SLC26A4	O43511-1.1	N324Q	Pathogenic	0.944
SLC26A4	O43511-1.1	N324R	Pathogenic	0.782
SLC26A4	O43511-1.1	N324S	Pathogenic	0.861
SLC26A4	O43511-1.1	N324T	Pathogenic	0.965
SLC26A4	O43511-1.1	N324V	Pathogenic	0.992
SLC26A4	O43511-1.1	N324W	Pathogenic	0.92
SLC26A4	O43511-1.1	N324Y	Pathogenic	0.927
SLC26A4	O43511-1.1	A325C	Pathogenic	0.733
SLC26A4	O43511-1.1	A325D	Pathogenic	0.883
SLC26A4	O43511-1.1	A325E	Pathogenic	0.637
SLC26A4	O43511-1.1	A325F	Neutral	0.471
SLC26A4	O43511-1.1	A325G	Pathogenic	0.76
SLC26A4	O43511-1.1	A325H	Pathogenic	0.76
SLC26A4	O43511-1.1	A325I	Neutral	0.42
SLC26A4	O43511-1.1	A325K	Neutral	0.322
SLC26A4	O43511-1.1	A325L	Neutral	0.429
SLC26A4	O43511-1.1	A325M	Neutral	0.474
SLC26A4	O43511-1.1	A325N	Pathogenic	0.866
SLC26A4	O43511-1.1	A325P	Pathogenic	0.836
SLC26A4	O43511-1.1	A325Q	Pathogenic	0.622
SLC26A4	O43511-1.1	A325R	Neutral	0.208
SLC26A4	O43511-1.1	A325S	Pathogenic	0.736
SLC26A4	O43511-1.1	A325T	Pathogenic	0.718
SLC26A4	O43511-1.1	A325V	Pathogenic	0.515
SLC26A4	O43511-1.1	A325W	Neutral	0.297
SLC26A4	O43511-1.1	A325Y	Neutral	0.483
SLC26A4	O43511-1.1	G326A	Neutral	0.483
SLC26A4	O43511-1.1	G326C	Pathogenic	0.712
SLC26A4	O43511-1.1	G326D	Neutral	0.347
SLC26A4	O43511-1.1	G326E	Neutral	0.333
SLC26A4	O43511-1.1	G326F	Neutral	0.166
SLC26A4	O43511-1.1	G326H	Neutral	0.287
SLC26A4	O43511-1.1	G326I	Neutral	0.395
SLC26A4	O43511-1.1	G326K	Neutral	0.119
SLC26A4	O43511-1.1	G326L	Neutral	0.404
SLC26A4	O43511-1.1	G326M	Neutral	0.288
SLC26A4	O43511-1.1	G326N	Neutral	0.184
SLC26A4	O43511-1.1	G326P	Pathogenic	0.532
SLC26A4	O43511-1.1	G326Q	Neutral	0.318
SLC26A4	O43511-1.1	G326R	Neutral	0.069
SLC26A4	O43511-1.1	G326S	Neutral	0.442
SLC26A4	O43511-1.1	G326T	Pathogenic	0.543
SLC26A4	O43511-1.1	G326V	Neutral	0.49
SLC26A4	O43511-1.1	G326W	Neutral	0.023
SLC26A4	O43511-1.1	G326Y	Neutral	0.173
SLC26A4	O43511-1.1	I327A	Neutral	0.437
SLC26A4	O43511-1.1	I327C	Pathogenic	0.704
SLC26A4	O43511-1.1	I327D	Pathogenic	0.859
SLC26A4	O43511-1.1	I327E	Pathogenic	0.935
SLC26A4	O43511-1.1	I327F	Pathogenic	0.845
SLC26A4	O43511-1.1	I327G	Pathogenic	0.704
SLC26A4	O43511-1.1	I327H	Pathogenic	0.967
SLC26A4	O43511-1.1	I327K	Pathogenic	0.938
SLC26A4	O43511-1.1	I327L	Pathogenic	0.682
SLC26A4	O43511-1.1	I327M	Pathogenic	0.783
SLC26A4	O43511-1.1	I327N	Pathogenic	0.891
SLC26A4	O43511-1.1	I327P	Pathogenic	0.912
SLC26A4	O43511-1.1	I327Q	Pathogenic	0.955
SLC26A4	O43511-1.1	I327R	Pathogenic	0.893
SLC26A4	O43511-1.1	I327S	Pathogenic	0.642
SLC26A4	O43511-1.1	I327T	Pathogenic	0.711
SLC26A4	O43511-1.1	I327V	Neutral	0.273
SLC26A4	O43511-1.1	I327W	Pathogenic	0.914
SLC26A4	O43511-1.1	I327Y	Pathogenic	0.859
SLC26A4	O43511-1.1	V328A	Pathogenic	0.896
SLC26A4	O43511-1.1	V328C	Pathogenic	0.981
SLC26A4	O43511-1.1	V328D	Pathogenic	0.993
SLC26A4	O43511-1.1	V328E	Pathogenic	0.991
SLC26A4	O43511-1.1	V328F	Pathogenic	0.966
SLC26A4	O43511-1.1	V328G	Pathogenic	0.963
SLC26A4	O43511-1.1	V328H	Pathogenic	0.995
SLC26A4	O43511-1.1	V328I	Pathogenic	0.74
SLC26A4	O43511-1.1	V328K	Pathogenic	0.968
SLC26A4	O43511-1.1	V328L	Pathogenic	0.923
SLC26A4	O43511-1.1	V328M	Pathogenic	0.935
SLC26A4	O43511-1.1	V328N	Pathogenic	0.995
SLC26A4	O43511-1.1	V328P	Pathogenic	0.991
SLC26A4	O43511-1.1	V328Q	Pathogenic	0.991
SLC26A4	O43511-1.1	V328R	Pathogenic	0.971
SLC26A4	O43511-1.1	V328S	Pathogenic	0.976
SLC26A4	O43511-1.1	V328T	Pathogenic	0.965
SLC26A4	O43511-1.1	V328W	Pathogenic	0.964
SLC26A4	O43511-1.1	V328Y	Pathogenic	0.961
SLC26A4	O43511-1.1	K329A	Neutral	0.421
SLC26A4	O43511-1.1	K329C	Pathogenic	0.842
SLC26A4	O43511-1.1	K329D	Pathogenic	0.765
SLC26A4	O43511-1.1	K329E	Pathogenic	0.633
SLC26A4	O43511-1.1	K329F	Pathogenic	0.973
SLC26A4	O43511-1.1	K329G	Neutral	0.411
SLC26A4	O43511-1.1	K329H	Pathogenic	0.886
SLC26A4	O43511-1.1	K329I	Pathogenic	0.956
SLC26A4	O43511-1.1	K329L	Pathogenic	0.918
SLC26A4	O43511-1.1	K329M	Pathogenic	0.87
SLC26A4	O43511-1.1	K329N	Pathogenic	0.655
SLC26A4	O43511-1.1	K329P	Pathogenic	0.637
SLC26A4	O43511-1.1	K329Q	Pathogenic	0.648
SLC26A4	O43511-1.1	K329R	Pathogenic	0.637
SLC26A4	O43511-1.1	K329S	Neutral	0.351
SLC26A4	O43511-1.1	K329T	Pathogenic	0.706
SLC26A4	O43511-1.1	K329V	Pathogenic	0.851
SLC26A4	O43511-1.1	K329W	Pathogenic	0.894
SLC26A4	O43511-1.1	K329Y	Pathogenic	0.949
SLC26A4	O43511-1.1	S330A	Neutral	0.147
SLC26A4	O43511-1.1	S330C	Neutral	0.281
SLC26A4	O43511-1.1	S330D	Neutral	0.148
SLC26A4	O43511-1.1	S330E	Neutral	0.075
SLC26A4	O43511-1.1	S330F	Neutral	0.059
SLC26A4	O43511-1.1	S330G	Neutral	0.142
SLC26A4	O43511-1.1	S330H	Neutral	0.113
SLC26A4	O43511-1.1	S330I	Neutral	0.093
SLC26A4	O43511-1.1	S330K	Neutral	0.021
SLC26A4	O43511-1.1	S330L	Neutral	0.097
SLC26A4	O43511-1.1	S330M	Neutral	0.06
SLC26A4	O43511-1.1	S330N	Neutral	0.068
SLC26A4	O43511-1.1	S330P	Neutral	0.265
SLC26A4	O43511-1.1	S330Q	Neutral	0.07
SLC26A4	O43511-1.1	S330R	Neutral	0.024
SLC26A4	O43511-1.1	S330T	Neutral	0.085
SLC26A4	O43511-1.1	S330V	Neutral	0.233
SLC26A4	O43511-1.1	S330W	Neutral	0.029
SLC26A4	O43511-1.1	S330Y	Neutral	0.062
SLC26A4	O43511-1.1	I331A	Neutral	0.364
SLC26A4	O43511-1.1	I331C	Pathogenic	0.636
SLC26A4	O43511-1.1	I331D	Pathogenic	0.818
SLC26A4	O43511-1.1	I331E	Pathogenic	0.914
SLC26A4	O43511-1.1	I331F	Pathogenic	0.801
SLC26A4	O43511-1.1	I331G	Pathogenic	0.636
SLC26A4	O43511-1.1	I331H	Pathogenic	0.956
SLC26A4	O43511-1.1	I331K	Pathogenic	0.918
SLC26A4	O43511-1.1	I331L	Pathogenic	0.613
SLC26A4	O43511-1.1	I331M	Pathogenic	0.726
SLC26A4	O43511-1.1	I331N	Pathogenic	0.858
SLC26A4	O43511-1.1	I331P	Pathogenic	0.884
SLC26A4	O43511-1.1	I331Q	Pathogenic	0.94
SLC26A4	O43511-1.1	I331R	Pathogenic	0.861
SLC26A4	O43511-1.1	I331S	Pathogenic	0.569
SLC26A4	O43511-1.1	I331T	Pathogenic	0.645
SLC26A4	O43511-1.1	I331V	Neutral	0.217
SLC26A4	O43511-1.1	I331W	Pathogenic	0.886
SLC26A4	O43511-1.1	I331Y	Pathogenic	0.817
SLC26A4	O43511-1.1	P332A	Pathogenic	0.892
SLC26A4	O43511-1.1	P332C	Pathogenic	0.988
SLC26A4	O43511-1.1	P332D	Pathogenic	0.937
SLC26A4	O43511-1.1	P332E	Pathogenic	0.873
SLC26A4	O43511-1.1	P332F	Pathogenic	0.951
SLC26A4	O43511-1.1	P332G	Pathogenic	0.863
SLC26A4	O43511-1.1	P332H	Pathogenic	0.926
SLC26A4	O43511-1.1	P332I	Pathogenic	0.94
SLC26A4	O43511-1.1	P332K	Pathogenic	0.651
SLC26A4	O43511-1.1	P332L	Pathogenic	0.942
SLC26A4	O43511-1.1	P332M	Pathogenic	0.907
SLC26A4	O43511-1.1	P332N	Pathogenic	0.962
SLC26A4	O43511-1.1	P332Q	Pathogenic	0.866
SLC26A4	O43511-1.1	P332R	Pathogenic	0.674
SLC26A4	O43511-1.1	P332S	Pathogenic	0.905
SLC26A4	O43511-1.1	P332T	Pathogenic	0.953
SLC26A4	O43511-1.1	P332V	Pathogenic	0.959
SLC26A4	O43511-1.1	P332W	Pathogenic	0.82
SLC26A4	O43511-1.1	P332Y	Pathogenic	0.91
SLC26A4	O43511-1.1	R333A	Neutral	0.03
SLC26A4	O43511-1.1	R333C	Neutral	0.184
SLC26A4	O43511-1.1	R333D	Neutral	0.217
SLC26A4	O43511-1.1	R333E	Neutral	0.128
SLC26A4	O43511-1.1	R333F	Pathogenic	0.602
SLC26A4	O43511-1.1	R333G	Neutral	0.029
SLC26A4	O43511-1.1	R333H	Neutral	0.141
SLC26A4	O43511-1.1	R333I	Neutral	0.478
SLC26A4	O43511-1.1	R333K	Neutral	0.119
SLC26A4	O43511-1.1	R333L	Neutral	0.322
SLC26A4	O43511-1.1	R333M	Neutral	0.22
SLC26A4	O43511-1.1	R333N	Neutral	0.075
SLC26A4	O43511-1.1	R333P	Neutral	0.13
SLC26A4	O43511-1.1	R333Q	Neutral	0.072
SLC26A4	O43511-1.1	R333S	Neutral	0.044
SLC26A4	O43511-1.1	R333T	Neutral	0.092
SLC26A4	O43511-1.1	R333V	Neutral	0.327
SLC26A4	O43511-1.1	R333W	Pathogenic	0.536
SLC26A4	O43511-1.1	R333Y	Pathogenic	0.576
SLC26A4	O43511-1.1	G334A	Pathogenic	0.994
SLC26A4	O43511-1.1	G334C	Pathogenic	0.998
SLC26A4	O43511-1.1	G334D	Pathogenic	0.99
SLC26A4	O43511-1.1	G334E	Pathogenic	0.989
SLC26A4	O43511-1.1	G334F	Pathogenic	0.973
SLC26A4	O43511-1.1	G334H	Pathogenic	0.987
SLC26A4	O43511-1.1	G334I	Pathogenic	0.992
SLC26A4	O43511-1.1	G334K	Pathogenic	0.961
SLC26A4	O43511-1.1	G334L	Pathogenic	0.992
SLC26A4	O43511-1.1	G334M	Pathogenic	0.987
SLC26A4	O43511-1.1	G334N	Pathogenic	0.976
SLC26A4	O43511-1.1	G334P	Pathogenic	0.995
SLC26A4	O43511-1.1	G334Q	Pathogenic	0.988
SLC26A4	O43511-1.1	G334R	Pathogenic	0.931
SLC26A4	O43511-1.1	G334S	Pathogenic	0.993
SLC26A4	O43511-1.1	G334T	Pathogenic	0.995
SLC26A4	O43511-1.1	G334V	Pathogenic	0.994
SLC26A4	O43511-1.1	G334W	Pathogenic	0.809
SLC26A4	O43511-1.1	G334Y	Pathogenic	0.974
SLC26A4	O43511-1.1	F335A	Pathogenic	0.915
SLC26A4	O43511-1.1	F335C	Pathogenic	0.97
SLC26A4	O43511-1.1	F335D	Pathogenic	0.977
SLC26A4	O43511-1.1	F335E	Pathogenic	0.99
SLC26A4	O43511-1.1	F335G	Pathogenic	0.89
SLC26A4	O43511-1.1	F335H	Pathogenic	0.98
SLC26A4	O43511-1.1	F335I	Pathogenic	0.984
SLC26A4	O43511-1.1	F335K	Pathogenic	0.996
SLC26A4	O43511-1.1	F335L	Pathogenic	0.983
SLC26A4	O43511-1.1	F335M	Pathogenic	0.98
SLC26A4	O43511-1.1	F335N	Pathogenic	0.983
SLC26A4	O43511-1.1	F335P	Pathogenic	0.993
SLC26A4	O43511-1.1	F335Q	Pathogenic	0.993
SLC26A4	O43511-1.1	F335R	Pathogenic	0.994
SLC26A4	O43511-1.1	F335S	Pathogenic	0.925
SLC26A4	O43511-1.1	F335T	Pathogenic	0.971
SLC26A4	O43511-1.1	F335V	Pathogenic	0.977
SLC26A4	O43511-1.1	F335W	Pathogenic	0.923
SLC26A4	O43511-1.1	F335Y	Pathogenic	0.874
SLC26A4	O43511-1.1	L336A	Neutral	0.049
SLC26A4	O43511-1.1	L336C	Neutral	0.137
SLC26A4	O43511-1.1	L336D	Neutral	0.451
SLC26A4	O43511-1.1	L336E	Neutral	0.492
SLC26A4	O43511-1.1	L336F	Neutral	0.254
SLC26A4	O43511-1.1	L336G	Neutral	0.137
SLC26A4	O43511-1.1	L336H	Pathogenic	0.662
SLC26A4	O43511-1.1	L336I	Neutral	0.121
SLC26A4	O43511-1.1	L336K	Neutral	0.335
SLC26A4	O43511-1.1	L336M	Neutral	0.107
SLC26A4	O43511-1.1	L336N	Neutral	0.354
SLC26A4	O43511-1.1	L336P	Neutral	0.41
SLC26A4	O43511-1.1	L336Q	Neutral	0.415
SLC26A4	O43511-1.1	L336R	Neutral	0.218
SLC26A4	O43511-1.1	L336S	Neutral	0.107
SLC26A4	O43511-1.1	L336T	Neutral	0.141
SLC26A4	O43511-1.1	L336V	Neutral	0.092
SLC26A4	O43511-1.1	L336W	Neutral	0.246
SLC26A4	O43511-1.1	L336Y	Neutral	0.289
SLC26A4	O43511-1.1	P337A	Pathogenic	0.907
SLC26A4	O43511-1.1	P337C	Pathogenic	0.99
SLC26A4	O43511-1.1	P337D	Pathogenic	0.946
SLC26A4	O43511-1.1	P337E	Pathogenic	0.89
SLC26A4	O43511-1.1	P337F	Pathogenic	0.958
SLC26A4	O43511-1.1	P337G	Pathogenic	0.881
SLC26A4	O43511-1.1	P337H	Pathogenic	0.936
SLC26A4	O43511-1.1	P337I	Pathogenic	0.949
SLC26A4	O43511-1.1	P337K	Pathogenic	0.687
SLC26A4	O43511-1.1	P337L	Pathogenic	0.951
SLC26A4	O43511-1.1	P337M	Pathogenic	0.92
SLC26A4	O43511-1.1	P337N	Pathogenic	0.967
SLC26A4	O43511-1.1	P337Q	Pathogenic	0.884
SLC26A4	O43511-1.1	P337R	Pathogenic	0.709
SLC26A4	O43511-1.1	P337S	Pathogenic	0.918
SLC26A4	O43511-1.1	P337T	Pathogenic	0.959
SLC26A4	O43511-1.1	P337V	Pathogenic	0.964
SLC26A4	O43511-1.1	P337W	Pathogenic	0.843
SLC26A4	O43511-1.1	P337Y	Pathogenic	0.922
SLC26A4	O43511-1.1	P338A	Pathogenic	0.998
SLC26A4	O43511-1.1	P338C	Pathogenic	1.0
SLC26A4	O43511-1.1	P338D	Pathogenic	0.999
SLC26A4	O43511-1.1	P338E	Pathogenic	0.998
SLC26A4	O43511-1.1	P338F	Pathogenic	0.999
SLC26A4	O43511-1.1	P338G	Pathogenic	0.998
SLC26A4	O43511-1.1	P338H	Pathogenic	0.999
SLC26A4	O43511-1.1	P338I	Pathogenic	0.999
SLC26A4	O43511-1.1	P338K	Pathogenic	0.992
SLC26A4	O43511-1.1	P338L	Pathogenic	0.999
SLC26A4	O43511-1.1	P338M	Pathogenic	0.998
SLC26A4	O43511-1.1	P338N	Pathogenic	0.999
SLC26A4	O43511-1.1	P338Q	Pathogenic	0.998
SLC26A4	O43511-1.1	P338R	Pathogenic	0.993
SLC26A4	O43511-1.1	P338S	Pathogenic	0.998
SLC26A4	O43511-1.1	P338T	Pathogenic	0.999
SLC26A4	O43511-1.1	P338V	Pathogenic	0.999
SLC26A4	O43511-1.1	P338W	Pathogenic	0.997
SLC26A4	O43511-1.1	P338Y	Pathogenic	0.999
SLC26A4	O43511-1.1	E339A	Neutral	0.034
SLC26A4	O43511-1.1	E339C	Neutral	0.34
SLC26A4	O43511-1.1	E339D	Neutral	0.017
SLC26A4	O43511-1.1	E339F	Neutral	0.141
SLC26A4	O43511-1.1	E339G	Neutral	0.032
SLC26A4	O43511-1.1	E339H	Neutral	0.076
SLC26A4	O43511-1.1	E339I	Neutral	0.211
SLC26A4	O43511-1.1	E339K	Neutral	0.022
SLC26A4	O43511-1.1	E339L	Neutral	0.218
SLC26A4	O43511-1.1	E339M	Neutral	0.142
SLC26A4	O43511-1.1	E339N	Neutral	0.084
SLC26A4	O43511-1.1	E339P	Neutral	0.078
SLC26A4	O43511-1.1	E339Q	Neutral	0.027
SLC26A4	O43511-1.1	E339R	Neutral	0.024
SLC26A4	O43511-1.1	E339S	Neutral	0.025
SLC26A4	O43511-1.1	E339T	Neutral	0.103
SLC26A4	O43511-1.1	E339V	Neutral	0.215
SLC26A4	O43511-1.1	E339W	Neutral	0.037
SLC26A4	O43511-1.1	E339Y	Neutral	0.079
SLC26A4	O43511-1.1	L340A	Neutral	0.007
SLC26A4	O43511-1.1	L340C	Neutral	0.021
SLC26A4	O43511-1.1	L340D	Neutral	0.098
SLC26A4	O43511-1.1	L340E	Neutral	0.114
SLC26A4	O43511-1.1	L340F	Neutral	0.043
SLC26A4	O43511-1.1	L340G	Neutral	0.021
SLC26A4	O43511-1.1	L340H	Neutral	0.206
SLC26A4	O43511-1.1	L340I	Neutral	0.018
SLC26A4	O43511-1.1	L340K	Neutral	0.063
SLC26A4	O43511-1.1	L340M	Neutral	0.016
SLC26A4	O43511-1.1	L340N	Neutral	0.067
SLC26A4	O43511-1.1	L340P	Neutral	0.084
SLC26A4	O43511-1.1	L340Q	Neutral	0.086
SLC26A4	O43511-1.1	L340R	Neutral	0.036
SLC26A4	O43511-1.1	L340S	Neutral	0.016
SLC26A4	O43511-1.1	L340T	Neutral	0.021
SLC26A4	O43511-1.1	L340V	Neutral	0.013
SLC26A4	O43511-1.1	L340W	Neutral	0.041
SLC26A4	O43511-1.1	L340Y	Neutral	0.051
SLC26A4	O43511-1.1	P341A	Pathogenic	0.998
SLC26A4	O43511-1.1	P341C	Pathogenic	1.0
SLC26A4	O43511-1.1	P341D	Pathogenic	0.999
SLC26A4	O43511-1.1	P341E	Pathogenic	0.997
SLC26A4	O43511-1.1	P341F	Pathogenic	0.999
SLC26A4	O43511-1.1	P341G	Pathogenic	0.997
SLC26A4	O43511-1.1	P341H	Pathogenic	0.998
SLC26A4	O43511-1.1	P341I	Pathogenic	0.999
SLC26A4	O43511-1.1	P341K	Pathogenic	0.99
SLC26A4	O43511-1.1	P341L	Pathogenic	0.999
SLC26A4	O43511-1.1	P341M	Pathogenic	0.998
SLC26A4	O43511-1.1	P341N	Pathogenic	0.999
SLC26A4	O43511-1.1	P341Q	Pathogenic	0.997
SLC26A4	O43511-1.1	P341R	Pathogenic	0.991
SLC26A4	O43511-1.1	P341S	Pathogenic	0.998
SLC26A4	O43511-1.1	P341T	Pathogenic	0.999
SLC26A4	O43511-1.1	P341V	Pathogenic	0.999
SLC26A4	O43511-1.1	P341W	Pathogenic	0.996
SLC26A4	O43511-1.1	P341Y	Pathogenic	0.998
SLC26A4	O43511-1.1	P342A	Neutral	0.207
SLC26A4	O43511-1.1	P342C	Pathogenic	0.725
SLC26A4	O43511-1.1	P342D	Neutral	0.318
SLC26A4	O43511-1.1	P342E	Neutral	0.179
SLC26A4	O43511-1.1	P342F	Neutral	0.378
SLC26A4	O43511-1.1	P342G	Neutral	0.165
SLC26A4	O43511-1.1	P342H	Neutral	0.281
SLC26A4	O43511-1.1	P342I	Neutral	0.331
SLC26A4	O43511-1.1	P342K	Neutral	0.055
SLC26A4	O43511-1.1	P342L	Neutral	0.34
SLC26A4	O43511-1.1	P342M	Neutral	0.235
SLC26A4	O43511-1.1	P342N	Neutral	0.443
SLC26A4	O43511-1.1	P342Q	Neutral	0.169
SLC26A4	O43511-1.1	P342R	Neutral	0.061
SLC26A4	O43511-1.1	P342S	Neutral	0.231
SLC26A4	O43511-1.1	P342T	Neutral	0.387
SLC26A4	O43511-1.1	P342V	Neutral	0.421
SLC26A4	O43511-1.1	P342W	Neutral	0.126
SLC26A4	O43511-1.1	P342Y	Neutral	0.241
SLC26A4	O43511-1.1	V343A	Neutral	0.247
SLC26A4	O43511-1.1	V343C	Pathogenic	0.668
SLC26A4	O43511-1.1	V343D	Pathogenic	0.838
SLC26A4	O43511-1.1	V343E	Pathogenic	0.81
SLC26A4	O43511-1.1	V343F	Pathogenic	0.519
SLC26A4	O43511-1.1	V343G	Pathogenic	0.501
SLC26A4	O43511-1.1	V343H	Pathogenic	0.885
SLC26A4	O43511-1.1	V343I	Neutral	0.098
SLC26A4	O43511-1.1	V343K	Pathogenic	0.536
SLC26A4	O43511-1.1	V343L	Neutral	0.312
SLC26A4	O43511-1.1	V343M	Neutral	0.352
SLC26A4	O43511-1.1	V343N	Pathogenic	0.874
SLC26A4	O43511-1.1	V343P	Pathogenic	0.814
SLC26A4	O43511-1.1	V343Q	Pathogenic	0.8
SLC26A4	O43511-1.1	V343R	Pathogenic	0.562
SLC26A4	O43511-1.1	V343S	Pathogenic	0.603
SLC26A4	O43511-1.1	V343T	Pathogenic	0.51
SLC26A4	O43511-1.1	V343W	Pathogenic	0.507
SLC26A4	O43511-1.1	V343Y	Neutral	0.481
SLC26A4	O43511-1.1	S344A	Neutral	0.093
SLC26A4	O43511-1.1	S344C	Neutral	0.189
SLC26A4	O43511-1.1	S344D	Neutral	0.094
SLC26A4	O43511-1.1	S344E	Neutral	0.046
SLC26A4	O43511-1.1	S344F	Neutral	0.036
SLC26A4	O43511-1.1	S344G	Neutral	0.09
SLC26A4	O43511-1.1	S344H	Neutral	0.071
SLC26A4	O43511-1.1	S344I	Neutral	0.058
SLC26A4	O43511-1.1	S344K	Neutral	0.013
SLC26A4	O43511-1.1	S344L	Neutral	0.06
SLC26A4	O43511-1.1	S344M	Neutral	0.037
SLC26A4	O43511-1.1	S344N	Neutral	0.042
SLC26A4	O43511-1.1	S344P	Neutral	0.177
SLC26A4	O43511-1.1	S344Q	Neutral	0.043
SLC26A4	O43511-1.1	S344R	Neutral	0.014
SLC26A4	O43511-1.1	S344T	Neutral	0.053
SLC26A4	O43511-1.1	S344V	Neutral	0.153
SLC26A4	O43511-1.1	S344W	Neutral	0.018
SLC26A4	O43511-1.1	S344Y	Neutral	0.038
SLC26A4	O43511-1.1	L345A	Neutral	0.045
SLC26A4	O43511-1.1	L345C	Neutral	0.125
SLC26A4	O43511-1.1	L345D	Neutral	0.426
SLC26A4	O43511-1.1	L345E	Neutral	0.467
SLC26A4	O43511-1.1	L345F	Neutral	0.235
SLC26A4	O43511-1.1	L345G	Neutral	0.125
SLC26A4	O43511-1.1	L345H	Pathogenic	0.639
SLC26A4	O43511-1.1	L345I	Neutral	0.111
SLC26A4	O43511-1.1	L345K	Neutral	0.313
SLC26A4	O43511-1.1	L345M	Neutral	0.098
SLC26A4	O43511-1.1	L345N	Neutral	0.331
SLC26A4	O43511-1.1	L345P	Neutral	0.385
SLC26A4	O43511-1.1	L345Q	Neutral	0.391
SLC26A4	O43511-1.1	L345R	Neutral	0.201
SLC26A4	O43511-1.1	L345S	Neutral	0.098
SLC26A4	O43511-1.1	L345T	Neutral	0.129
SLC26A4	O43511-1.1	L345V	Neutral	0.084
SLC26A4	O43511-1.1	L345W	Neutral	0.227
SLC26A4	O43511-1.1	L345Y	Neutral	0.269
SLC26A4	O43511-1.1	F346A	Pathogenic	0.719
SLC26A4	O43511-1.1	F346C	Pathogenic	0.887
SLC26A4	O43511-1.1	F346D	Pathogenic	0.909
SLC26A4	O43511-1.1	F346E	Pathogenic	0.96
SLC26A4	O43511-1.1	F346G	Pathogenic	0.66
SLC26A4	O43511-1.1	F346H	Pathogenic	0.923
SLC26A4	O43511-1.1	F346I	Pathogenic	0.936
SLC26A4	O43511-1.1	F346K	Pathogenic	0.985
SLC26A4	O43511-1.1	F346L	Pathogenic	0.934
SLC26A4	O43511-1.1	F346M	Pathogenic	0.922
SLC26A4	O43511-1.1	F346N	Pathogenic	0.931
SLC26A4	O43511-1.1	F346P	Pathogenic	0.972
SLC26A4	O43511-1.1	F346Q	Pathogenic	0.972
SLC26A4	O43511-1.1	F346R	Pathogenic	0.974
SLC26A4	O43511-1.1	F346S	Pathogenic	0.746
SLC26A4	O43511-1.1	F346T	Pathogenic	0.89
SLC26A4	O43511-1.1	F346V	Pathogenic	0.91
SLC26A4	O43511-1.1	F346W	Pathogenic	0.74
SLC26A4	O43511-1.1	F346Y	Pathogenic	0.623
SLC26A4	O43511-1.1	S347A	Neutral	0.313
SLC26A4	O43511-1.1	S347C	Pathogenic	0.509
SLC26A4	O43511-1.1	S347D	Neutral	0.315
SLC26A4	O43511-1.1	S347E	Neutral	0.177
SLC26A4	O43511-1.1	S347F	Neutral	0.143
SLC26A4	O43511-1.1	S347G	Neutral	0.305
SLC26A4	O43511-1.1	S347H	Neutral	0.253
SLC26A4	O43511-1.1	S347I	Neutral	0.214
SLC26A4	O43511-1.1	S347K	Neutral	0.055
SLC26A4	O43511-1.1	S347L	Neutral	0.221
SLC26A4	O43511-1.1	S347M	Neutral	0.145
SLC26A4	O43511-1.1	S347N	Neutral	0.163
SLC26A4	O43511-1.1	S347P	Neutral	0.489
SLC26A4	O43511-1.1	S347Q	Neutral	0.167
SLC26A4	O43511-1.1	S347R	Neutral	0.06
SLC26A4	O43511-1.1	S347T	Neutral	0.198
SLC26A4	O43511-1.1	S347V	Neutral	0.446
SLC26A4	O43511-1.1	S347W	Neutral	0.073
SLC26A4	O43511-1.1	S347Y	Neutral	0.149
SLC26A4	O43511-1.1	E348A	Neutral	0.119
SLC26A4	O43511-1.1	E348C	Pathogenic	0.665
SLC26A4	O43511-1.1	E348D	Neutral	0.063
SLC26A4	O43511-1.1	E348F	Neutral	0.388
SLC26A4	O43511-1.1	E348G	Neutral	0.115
SLC26A4	O43511-1.1	E348H	Neutral	0.242
SLC26A4	O43511-1.1	E348I	Pathogenic	0.509
SLC26A4	O43511-1.1	E348K	Neutral	0.08
SLC26A4	O43511-1.1	E348L	Pathogenic	0.518
SLC26A4	O43511-1.1	E348M	Neutral	0.391
SLC26A4	O43511-1.1	E348N	Neutral	0.261
SLC26A4	O43511-1.1	E348P	Neutral	0.245
SLC26A4	O43511-1.1	E348Q	Neutral	0.098
SLC26A4	O43511-1.1	E348R	Neutral	0.088
SLC26A4	O43511-1.1	E348S	Neutral	0.091
SLC26A4	O43511-1.1	E348T	Neutral	0.308
SLC26A4	O43511-1.1	E348V	Pathogenic	0.515
SLC26A4	O43511-1.1	E348W	Neutral	0.13
SLC26A4	O43511-1.1	E348Y	Neutral	0.249
SLC26A4	O43511-1.1	M349A	Pathogenic	0.565
SLC26A4	O43511-1.1	M349C	Pathogenic	0.799
SLC26A4	O43511-1.1	M349D	Pathogenic	0.911
SLC26A4	O43511-1.1	M349E	Pathogenic	0.923
SLC26A4	O43511-1.1	M349F	Pathogenic	0.856
SLC26A4	O43511-1.1	M349G	Pathogenic	0.664
SLC26A4	O43511-1.1	M349H	Pathogenic	0.961
SLC26A4	O43511-1.1	M349I	Pathogenic	0.829
SLC26A4	O43511-1.1	M349K	Pathogenic	0.863
SLC26A4	O43511-1.1	M349L	Pathogenic	0.714
SLC26A4	O43511-1.1	M349N	Pathogenic	0.872
SLC26A4	O43511-1.1	M349P	Pathogenic	0.896
SLC26A4	O43511-1.1	M349Q	Pathogenic	0.815
SLC26A4	O43511-1.1	M349R	Pathogenic	0.777
SLC26A4	O43511-1.1	M349S	Pathogenic	0.599
SLC26A4	O43511-1.1	M349T	Pathogenic	0.805
SLC26A4	O43511-1.1	M349V	Pathogenic	0.718
SLC26A4	O43511-1.1	M349W	Pathogenic	0.738
SLC26A4	O43511-1.1	M349Y	Pathogenic	0.91
SLC26A4	O43511-1.1	L350A	Neutral	0.022
SLC26A4	O43511-1.1	L350C	Neutral	0.065
SLC26A4	O43511-1.1	L350D	Neutral	0.266
SLC26A4	O43511-1.1	L350E	Neutral	0.3
SLC26A4	O43511-1.1	L350F	Neutral	0.131
SLC26A4	O43511-1.1	L350G	Neutral	0.065
SLC26A4	O43511-1.1	L350H	Neutral	0.463
SLC26A4	O43511-1.1	L350I	Neutral	0.057
SLC26A4	O43511-1.1	L350K	Neutral	0.182
SLC26A4	O43511-1.1	L350M	Neutral	0.05
SLC26A4	O43511-1.1	L350N	Neutral	0.194
SLC26A4	O43511-1.1	L350P	Neutral	0.234
SLC26A4	O43511-1.1	L350Q	Neutral	0.239
SLC26A4	O43511-1.1	L350R	Neutral	0.11
SLC26A4	O43511-1.1	L350S	Neutral	0.05
SLC26A4	O43511-1.1	L350T	Neutral	0.068
SLC26A4	O43511-1.1	L350V	Neutral	0.043
SLC26A4	O43511-1.1	L350W	Neutral	0.126
SLC26A4	O43511-1.1	L350Y	Neutral	0.152
SLC26A4	O43511-1.1	A351C	Neutral	0.13
SLC26A4	O43511-1.1	A351D	Neutral	0.292
SLC26A4	O43511-1.1	A351E	Neutral	0.088
SLC26A4	O43511-1.1	A351F	Neutral	0.046
SLC26A4	O43511-1.1	A351G	Neutral	0.147
SLC26A4	O43511-1.1	A351H	Neutral	0.147
SLC26A4	O43511-1.1	A351I	Neutral	0.038
SLC26A4	O43511-1.1	A351K	Neutral	0.025
SLC26A4	O43511-1.1	A351L	Neutral	0.039
SLC26A4	O43511-1.1	A351M	Neutral	0.047
SLC26A4	O43511-1.1	A351N	Neutral	0.26
SLC26A4	O43511-1.1	A351P	Neutral	0.218
SLC26A4	O43511-1.1	A351Q	Neutral	0.083
SLC26A4	O43511-1.1	A351R	Neutral	0.014
SLC26A4	O43511-1.1	A351S	Neutral	0.132
SLC26A4	O43511-1.1	A351T	Neutral	0.122
SLC26A4	O43511-1.1	A351V	Neutral	0.055
SLC26A4	O43511-1.1	A351W	Neutral	0.023
SLC26A4	O43511-1.1	A351Y	Neutral	0.049
SLC26A4	O43511-1.1	A352C	Neutral	0.426
SLC26A4	O43511-1.1	A352D	Pathogenic	0.672
SLC26A4	O43511-1.1	A352E	Neutral	0.322
SLC26A4	O43511-1.1	A352F	Neutral	0.194
SLC26A4	O43511-1.1	A352G	Neutral	0.461
SLC26A4	O43511-1.1	A352H	Neutral	0.461
SLC26A4	O43511-1.1	A352I	Neutral	0.164
SLC26A4	O43511-1.1	A352K	Neutral	0.114
SLC26A4	O43511-1.1	A352L	Neutral	0.169
SLC26A4	O43511-1.1	A352M	Neutral	0.196
SLC26A4	O43511-1.1	A352N	Pathogenic	0.636
SLC26A4	O43511-1.1	A352P	Pathogenic	0.58
SLC26A4	O43511-1.1	A352Q	Neutral	0.309
SLC26A4	O43511-1.1	A352R	Neutral	0.066
SLC26A4	O43511-1.1	A352S	Neutral	0.43
SLC26A4	O43511-1.1	A352T	Neutral	0.408
SLC26A4	O43511-1.1	A352V	Neutral	0.224
SLC26A4	O43511-1.1	A352W	Neutral	0.103
SLC26A4	O43511-1.1	A352Y	Neutral	0.202
SLC26A4	O43511-1.1	S353A	Pathogenic	0.684
SLC26A4	O43511-1.1	S353C	Pathogenic	0.831
SLC26A4	O43511-1.1	S353D	Pathogenic	0.685
SLC26A4	O43511-1.1	S353E	Pathogenic	0.504
SLC26A4	O43511-1.1	S353F	Neutral	0.442
SLC26A4	O43511-1.1	S353G	Pathogenic	0.675
SLC26A4	O43511-1.1	S353H	Pathogenic	0.616
SLC26A4	O43511-1.1	S353I	Pathogenic	0.564
SLC26A4	O43511-1.1	S353K	Neutral	0.215
SLC26A4	O43511-1.1	S353L	Pathogenic	0.574
SLC26A4	O43511-1.1	S353M	Neutral	0.445
SLC26A4	O43511-1.1	S353N	Neutral	0.48
SLC26A4	O43511-1.1	S353P	Pathogenic	0.819
SLC26A4	O43511-1.1	S353Q	Neutral	0.488
SLC26A4	O43511-1.1	S353R	Neutral	0.234
SLC26A4	O43511-1.1	S353T	Pathogenic	0.54
SLC26A4	O43511-1.1	S353V	Pathogenic	0.793
SLC26A4	O43511-1.1	S353W	Neutral	0.273
SLC26A4	O43511-1.1	S353Y	Neutral	0.454
SLC26A4	O43511-1.1	F354A	Pathogenic	0.822
SLC26A4	O43511-1.1	F354C	Pathogenic	0.934
SLC26A4	O43511-1.1	F354D	Pathogenic	0.948
SLC26A4	O43511-1.1	F354E	Pathogenic	0.977
SLC26A4	O43511-1.1	F354G	Pathogenic	0.778
SLC26A4	O43511-1.1	F354H	Pathogenic	0.955
SLC26A4	O43511-1.1	F354I	Pathogenic	0.963
SLC26A4	O43511-1.1	F354K	Pathogenic	0.992
SLC26A4	O43511-1.1	F354L	Pathogenic	0.962
SLC26A4	O43511-1.1	F354M	Pathogenic	0.955
SLC26A4	O43511-1.1	F354N	Pathogenic	0.96
SLC26A4	O43511-1.1	F354P	Pathogenic	0.984
SLC26A4	O43511-1.1	F354Q	Pathogenic	0.984
SLC26A4	O43511-1.1	F354R	Pathogenic	0.985
SLC26A4	O43511-1.1	F354S	Pathogenic	0.841
SLC26A4	O43511-1.1	F354T	Pathogenic	0.936
SLC26A4	O43511-1.1	F354V	Pathogenic	0.948
SLC26A4	O43511-1.1	F354W	Pathogenic	0.837
SLC26A4	O43511-1.1	F354Y	Pathogenic	0.749
SLC26A4	O43511-1.1	S355A	Pathogenic	0.765
SLC26A4	O43511-1.1	S355C	Pathogenic	0.881
SLC26A4	O43511-1.1	S355D	Pathogenic	0.766
SLC26A4	O43511-1.1	S355E	Pathogenic	0.605
SLC26A4	O43511-1.1	S355F	Pathogenic	0.544
SLC26A4	O43511-1.1	S355G	Pathogenic	0.758
SLC26A4	O43511-1.1	S355H	Pathogenic	0.708
SLC26A4	O43511-1.1	S355I	Pathogenic	0.661
SLC26A4	O43511-1.1	S355K	Neutral	0.293
SLC26A4	O43511-1.1	S355L	Pathogenic	0.67
SLC26A4	O43511-1.1	S355M	Pathogenic	0.547
SLC26A4	O43511-1.1	S355N	Pathogenic	0.582
SLC26A4	O43511-1.1	S355P	Pathogenic	0.872
SLC26A4	O43511-1.1	S355Q	Pathogenic	0.589
SLC26A4	O43511-1.1	S355R	Neutral	0.315
SLC26A4	O43511-1.1	S355T	Pathogenic	0.639
SLC26A4	O43511-1.1	S355V	Pathogenic	0.852
SLC26A4	O43511-1.1	S355W	Neutral	0.362
SLC26A4	O43511-1.1	S355Y	Pathogenic	0.556
SLC26A4	O43511-1.1	I356A	Pathogenic	0.855
SLC26A4	O43511-1.1	I356C	Pathogenic	0.947
SLC26A4	O43511-1.1	I356D	Pathogenic	0.979
SLC26A4	O43511-1.1	I356E	Pathogenic	0.991
SLC26A4	O43511-1.1	I356F	Pathogenic	0.976
SLC26A4	O43511-1.1	I356G	Pathogenic	0.947
SLC26A4	O43511-1.1	I356H	Pathogenic	0.996
SLC26A4	O43511-1.1	I356K	Pathogenic	0.991
SLC26A4	O43511-1.1	I356L	Pathogenic	0.942
SLC26A4	O43511-1.1	I356M	Pathogenic	0.965
SLC26A4	O43511-1.1	I356N	Pathogenic	0.984
SLC26A4	O43511-1.1	I356P	Pathogenic	0.987
SLC26A4	O43511-1.1	I356Q	Pathogenic	0.994
SLC26A4	O43511-1.1	I356R	Pathogenic	0.985
SLC26A4	O43511-1.1	I356S	Pathogenic	0.931
SLC26A4	O43511-1.1	I356T	Pathogenic	0.949
SLC26A4	O43511-1.1	I356V	Pathogenic	0.74
SLC26A4	O43511-1.1	I356W	Pathogenic	0.988
SLC26A4	O43511-1.1	I356Y	Pathogenic	0.979
SLC26A4	O43511-1.1	A357C	Pathogenic	0.975
SLC26A4	O43511-1.1	A357D	Pathogenic	0.991
SLC26A4	O43511-1.1	A357E	Pathogenic	0.961
SLC26A4	O43511-1.1	A357F	Pathogenic	0.927
SLC26A4	O43511-1.1	A357G	Pathogenic	0.978
SLC26A4	O43511-1.1	A357H	Pathogenic	0.978
SLC26A4	O43511-1.1	A357I	Pathogenic	0.911
SLC26A4	O43511-1.1	A357K	Pathogenic	0.871
SLC26A4	O43511-1.1	A357L	Pathogenic	0.914
SLC26A4	O43511-1.1	A357M	Pathogenic	0.927
SLC26A4	O43511-1.1	A357N	Pathogenic	0.989
SLC26A4	O43511-1.1	A357P	Pathogenic	0.986
SLC26A4	O43511-1.1	A357Q	Pathogenic	0.959
SLC26A4	O43511-1.1	A357R	Pathogenic	0.788
SLC26A4	O43511-1.1	A357S	Pathogenic	0.975
SLC26A4	O43511-1.1	A357T	Pathogenic	0.973
SLC26A4	O43511-1.1	A357V	Pathogenic	0.938
SLC26A4	O43511-1.1	A357W	Pathogenic	0.857
SLC26A4	O43511-1.1	A357Y	Pathogenic	0.93
SLC26A4	O43511-1.1	V358A	Neutral	0.221
SLC26A4	O43511-1.1	V358C	Pathogenic	0.636
SLC26A4	O43511-1.1	V358D	Pathogenic	0.818
SLC26A4	O43511-1.1	V358E	Pathogenic	0.787
SLC26A4	O43511-1.1	V358F	Neutral	0.483
SLC26A4	O43511-1.1	V358G	Neutral	0.465
SLC26A4	O43511-1.1	V358H	Pathogenic	0.869
SLC26A4	O43511-1.1	V358I	Neutral	0.086
SLC26A4	O43511-1.1	V358K	Neutral	0.5
SLC26A4	O43511-1.1	V358L	Neutral	0.282
SLC26A4	O43511-1.1	V358M	Neutral	0.32
SLC26A4	O43511-1.1	V358N	Pathogenic	0.857
SLC26A4	O43511-1.1	V358P	Pathogenic	0.792
SLC26A4	O43511-1.1	V358Q	Pathogenic	0.776
SLC26A4	O43511-1.1	V358R	Pathogenic	0.526
SLC26A4	O43511-1.1	V358S	Pathogenic	0.569
SLC26A4	O43511-1.1	V358T	Neutral	0.474
SLC26A4	O43511-1.1	V358W	Neutral	0.471
SLC26A4	O43511-1.1	V358Y	Neutral	0.446
SLC26A4	O43511-1.1	V359A	Pathogenic	0.957
SLC26A4	O43511-1.1	V359C	Pathogenic	0.993
SLC26A4	O43511-1.1	V359D	Pathogenic	0.997
SLC26A4	O43511-1.1	V359E	Pathogenic	0.997
SLC26A4	O43511-1.1	V359F	Pathogenic	0.987
SLC26A4	O43511-1.1	V359G	Pathogenic	0.986
SLC26A4	O43511-1.1	V359H	Pathogenic	0.998
SLC26A4	O43511-1.1	V359I	Pathogenic	0.88
SLC26A4	O43511-1.1	V359K	Pathogenic	0.987
SLC26A4	O43511-1.1	V359L	Pathogenic	0.969
SLC26A4	O43511-1.1	V359M	Pathogenic	0.974
SLC26A4	O43511-1.1	V359N	Pathogenic	0.998
SLC26A4	O43511-1.1	V359P	Pathogenic	0.997
SLC26A4	O43511-1.1	V359Q	Pathogenic	0.996
SLC26A4	O43511-1.1	V359R	Pathogenic	0.989
SLC26A4	O43511-1.1	V359S	Pathogenic	0.99
SLC26A4	O43511-1.1	V359T	Pathogenic	0.986
SLC26A4	O43511-1.1	V359W	Pathogenic	0.986
SLC26A4	O43511-1.1	V359Y	Pathogenic	0.984
SLC26A4	O43511-1.1	A360C	Pathogenic	0.759
SLC26A4	O43511-1.1	A360D	Pathogenic	0.897
SLC26A4	O43511-1.1	A360E	Pathogenic	0.669
SLC26A4	O43511-1.1	A360F	Pathogenic	0.505
SLC26A4	O43511-1.1	A360G	Pathogenic	0.784
SLC26A4	O43511-1.1	A360H	Pathogenic	0.784
SLC26A4	O43511-1.1	A360I	Neutral	0.454
SLC26A4	O43511-1.1	A360K	Neutral	0.353
SLC26A4	O43511-1.1	A360L	Neutral	0.463
SLC26A4	O43511-1.1	A360M	Pathogenic	0.509
SLC26A4	O43511-1.1	A360N	Pathogenic	0.881
SLC26A4	O43511-1.1	A360P	Pathogenic	0.854
SLC26A4	O43511-1.1	A360Q	Pathogenic	0.654
SLC26A4	O43511-1.1	A360R	Neutral	0.232
SLC26A4	O43511-1.1	A360S	Pathogenic	0.762
SLC26A4	O43511-1.1	A360T	Pathogenic	0.745
SLC26A4	O43511-1.1	A360V	Pathogenic	0.55
SLC26A4	O43511-1.1	A360W	Neutral	0.327
SLC26A4	O43511-1.1	A360Y	Pathogenic	0.517
SLC26A4	O43511-1.1	Y361A	Pathogenic	0.851
SLC26A4	O43511-1.1	Y361C	Pathogenic	0.945
SLC26A4	O43511-1.1	Y361D	Pathogenic	0.957
SLC26A4	O43511-1.1	Y361E	Pathogenic	0.963
SLC26A4	O43511-1.1	Y361F	Pathogenic	0.778
SLC26A4	O43511-1.1	Y361G	Pathogenic	0.812
SLC26A4	O43511-1.1	Y361H	Pathogenic	0.766
SLC26A4	O43511-1.1	Y361I	Pathogenic	0.972
SLC26A4	O43511-1.1	Y361K	Pathogenic	0.987
SLC26A4	O43511-1.1	Y361L	Pathogenic	0.973
SLC26A4	O43511-1.1	Y361M	Pathogenic	0.977
SLC26A4	O43511-1.1	Y361N	Pathogenic	0.937
SLC26A4	O43511-1.1	Y361P	Pathogenic	0.974
SLC26A4	O43511-1.1	Y361Q	Pathogenic	0.951
SLC26A4	O43511-1.1	Y361R	Pathogenic	0.986
SLC26A4	O43511-1.1	Y361S	Pathogenic	0.868
SLC26A4	O43511-1.1	Y361T	Pathogenic	0.948
SLC26A4	O43511-1.1	Y361V	Pathogenic	0.948
SLC26A4	O43511-1.1	Y361W	Pathogenic	0.741
SLC26A4	O43511-1.1	A362C	Pathogenic	0.963
SLC26A4	O43511-1.1	A362D	Pathogenic	0.986
SLC26A4	O43511-1.1	A362E	Pathogenic	0.944
SLC26A4	O43511-1.1	A362F	Pathogenic	0.895
SLC26A4	O43511-1.1	A362G	Pathogenic	0.968
SLC26A4	O43511-1.1	A362H	Pathogenic	0.968
SLC26A4	O43511-1.1	A362I	Pathogenic	0.874
SLC26A4	O43511-1.1	A362K	Pathogenic	0.82
SLC26A4	O43511-1.1	A362L	Pathogenic	0.878
SLC26A4	O43511-1.1	A362M	Pathogenic	0.896
SLC26A4	O43511-1.1	A362N	Pathogenic	0.984
SLC26A4	O43511-1.1	A362P	Pathogenic	0.98
SLC26A4	O43511-1.1	A362Q	Pathogenic	0.94
SLC26A4	O43511-1.1	A362R	Pathogenic	0.715
SLC26A4	O43511-1.1	A362S	Pathogenic	0.964
SLC26A4	O43511-1.1	A362T	Pathogenic	0.961
SLC26A4	O43511-1.1	A362V	Pathogenic	0.91
SLC26A4	O43511-1.1	A362W	Pathogenic	0.802
SLC26A4	O43511-1.1	A362Y	Pathogenic	0.899
SLC26A4	O43511-1.1	I363A	Neutral	0.201
SLC26A4	O43511-1.1	I363C	Neutral	0.435
SLC26A4	O43511-1.1	I363D	Pathogenic	0.665
SLC26A4	O43511-1.1	I363E	Pathogenic	0.825
SLC26A4	O43511-1.1	I363F	Pathogenic	0.639
SLC26A4	O43511-1.1	I363G	Neutral	0.435
SLC26A4	O43511-1.1	I363H	Pathogenic	0.905
SLC26A4	O43511-1.1	I363K	Pathogenic	0.831
SLC26A4	O43511-1.1	I363L	Neutral	0.411
SLC26A4	O43511-1.1	I363M	Pathogenic	0.539
SLC26A4	O43511-1.1	I363N	Pathogenic	0.726
SLC26A4	O43511-1.1	I363P	Pathogenic	0.771
SLC26A4	O43511-1.1	I363Q	Pathogenic	0.874
SLC26A4	O43511-1.1	I363R	Pathogenic	0.731
SLC26A4	O43511-1.1	I363S	Neutral	0.368
SLC26A4	O43511-1.1	I363T	Neutral	0.444
SLC26A4	O43511-1.1	I363V	Neutral	0.109
SLC26A4	O43511-1.1	I363W	Pathogenic	0.775
SLC26A4	O43511-1.1	I363Y	Pathogenic	0.664
SLC26A4	O43511-1.1	A364C	Pathogenic	0.983
SLC26A4	O43511-1.1	A364D	Pathogenic	0.994
SLC26A4	O43511-1.1	A364E	Pathogenic	0.974
SLC26A4	O43511-1.1	A364F	Pathogenic	0.951
SLC26A4	O43511-1.1	A364G	Pathogenic	0.986
SLC26A4	O43511-1.1	A364H	Pathogenic	0.986
SLC26A4	O43511-1.1	A364I	Pathogenic	0.94
SLC26A4	O43511-1.1	A364K	Pathogenic	0.912
SLC26A4	O43511-1.1	A364L	Pathogenic	0.942
SLC26A4	O43511-1.1	A364M	Pathogenic	0.951
SLC26A4	O43511-1.1	A364N	Pathogenic	0.993
SLC26A4	O43511-1.1	A364P	Pathogenic	0.991
SLC26A4	O43511-1.1	A364Q	Pathogenic	0.973
SLC26A4	O43511-1.1	A364R	Pathogenic	0.851
SLC26A4	O43511-1.1	A364S	Pathogenic	0.984
SLC26A4	O43511-1.1	A364T	Pathogenic	0.982
SLC26A4	O43511-1.1	A364V	Pathogenic	0.958
SLC26A4	O43511-1.1	A364W	Pathogenic	0.902
SLC26A4	O43511-1.1	A364Y	Pathogenic	0.953
SLC26A4	O43511-1.1	V365A	Neutral	0.364
SLC26A4	O43511-1.1	V365C	Pathogenic	0.779
SLC26A4	O43511-1.1	V365D	Pathogenic	0.901
SLC26A4	O43511-1.1	V365E	Pathogenic	0.882
SLC26A4	O43511-1.1	V365F	Pathogenic	0.653
SLC26A4	O43511-1.1	V365G	Pathogenic	0.636
SLC26A4	O43511-1.1	V365H	Pathogenic	0.931
SLC26A4	O43511-1.1	V365I	Neutral	0.159
SLC26A4	O43511-1.1	V365K	Pathogenic	0.668
SLC26A4	O43511-1.1	V365L	Neutral	0.442
SLC26A4	O43511-1.1	V365M	Neutral	0.487
SLC26A4	O43511-1.1	V365N	Pathogenic	0.924
SLC26A4	O43511-1.1	V365P	Pathogenic	0.884
SLC26A4	O43511-1.1	V365Q	Pathogenic	0.875
SLC26A4	O43511-1.1	V365R	Pathogenic	0.691
SLC26A4	O43511-1.1	V365S	Pathogenic	0.726
SLC26A4	O43511-1.1	V365T	Pathogenic	0.645
SLC26A4	O43511-1.1	V365W	Pathogenic	0.642
SLC26A4	O43511-1.1	V365Y	Pathogenic	0.618
SLC26A4	O43511-1.1	S366A	Pathogenic	0.991
SLC26A4	O43511-1.1	S366C	Pathogenic	0.996
SLC26A4	O43511-1.1	S366D	Pathogenic	0.991
SLC26A4	O43511-1.1	S366E	Pathogenic	0.981
SLC26A4	O43511-1.1	S366F	Pathogenic	0.976
SLC26A4	O43511-1.1	S366G	Pathogenic	0.991
SLC26A4	O43511-1.1	S366H	Pathogenic	0.988
SLC26A4	O43511-1.1	S366I	Pathogenic	0.985
SLC26A4	O43511-1.1	S366K	Pathogenic	0.934
SLC26A4	O43511-1.1	S366L	Pathogenic	0.986
SLC26A4	O43511-1.1	S366M	Pathogenic	0.977
SLC26A4	O43511-1.1	S366N	Pathogenic	0.98
SLC26A4	O43511-1.1	S366P	Pathogenic	0.996
SLC26A4	O43511-1.1	S366Q	Pathogenic	0.98
SLC26A4	O43511-1.1	S366R	Pathogenic	0.941
SLC26A4	O43511-1.1	S366T	Pathogenic	0.984
SLC26A4	O43511-1.1	S366V	Pathogenic	0.995
SLC26A4	O43511-1.1	S366W	Pathogenic	0.951
SLC26A4	O43511-1.1	S366Y	Pathogenic	0.977
SLC26A4	O43511-1.1	V367A	Pathogenic	0.922
SLC26A4	O43511-1.1	V367C	Pathogenic	0.986
SLC26A4	O43511-1.1	V367D	Pathogenic	0.995
SLC26A4	O43511-1.1	V367E	Pathogenic	0.994
SLC26A4	O43511-1.1	V367F	Pathogenic	0.975
SLC26A4	O43511-1.1	V367G	Pathogenic	0.973
SLC26A4	O43511-1.1	V367H	Pathogenic	0.996
SLC26A4	O43511-1.1	V367I	Pathogenic	0.796
SLC26A4	O43511-1.1	V367K	Pathogenic	0.977
SLC26A4	O43511-1.1	V367L	Pathogenic	0.942
SLC26A4	O43511-1.1	V367M	Pathogenic	0.952
SLC26A4	O43511-1.1	V367N	Pathogenic	0.996
SLC26A4	O43511-1.1	V367P	Pathogenic	0.994
SLC26A4	O43511-1.1	V367Q	Pathogenic	0.993
SLC26A4	O43511-1.1	V367R	Pathogenic	0.979
SLC26A4	O43511-1.1	V367S	Pathogenic	0.982
SLC26A4	O43511-1.1	V367T	Pathogenic	0.974
SLC26A4	O43511-1.1	V367W	Pathogenic	0.974
SLC26A4	O43511-1.1	V367Y	Pathogenic	0.971
SLC26A4	O43511-1.1	G368A	Pathogenic	0.848
SLC26A4	O43511-1.1	G368C	Pathogenic	0.937
SLC26A4	O43511-1.1	G368D	Pathogenic	0.76
SLC26A4	O43511-1.1	G368E	Pathogenic	0.748
SLC26A4	O43511-1.1	G368F	Pathogenic	0.542
SLC26A4	O43511-1.1	G368H	Pathogenic	0.707
SLC26A4	O43511-1.1	G368I	Pathogenic	0.796
SLC26A4	O43511-1.1	G368K	Neutral	0.445
SLC26A4	O43511-1.1	G368L	Pathogenic	0.802
SLC26A4	O43511-1.1	G368M	Pathogenic	0.707
SLC26A4	O43511-1.1	G368N	Pathogenic	0.573
SLC26A4	O43511-1.1	G368P	Pathogenic	0.872
SLC26A4	O43511-1.1	G368Q	Pathogenic	0.736
SLC26A4	O43511-1.1	G368R	Neutral	0.308
SLC26A4	O43511-1.1	G368S	Pathogenic	0.825
SLC26A4	O43511-1.1	G368T	Pathogenic	0.876
SLC26A4	O43511-1.1	G368V	Pathogenic	0.851
SLC26A4	O43511-1.1	G368W	Neutral	0.122
SLC26A4	O43511-1.1	G368Y	Pathogenic	0.554
SLC26A4	O43511-1.1	K369A	Pathogenic	0.837
SLC26A4	O43511-1.1	K369C	Pathogenic	0.974
SLC26A4	O43511-1.1	K369D	Pathogenic	0.958
SLC26A4	O43511-1.1	K369E	Pathogenic	0.924
SLC26A4	O43511-1.1	K369F	Pathogenic	0.996
SLC26A4	O43511-1.1	K369G	Pathogenic	0.831
SLC26A4	O43511-1.1	K369H	Pathogenic	0.982
SLC26A4	O43511-1.1	K369I	Pathogenic	0.993
SLC26A4	O43511-1.1	K369L	Pathogenic	0.987
SLC26A4	O43511-1.1	K369M	Pathogenic	0.979
SLC26A4	O43511-1.1	K369N	Pathogenic	0.931
SLC26A4	O43511-1.1	K369P	Pathogenic	0.925
SLC26A4	O43511-1.1	K369Q	Pathogenic	0.928
SLC26A4	O43511-1.1	K369R	Pathogenic	0.925
SLC26A4	O43511-1.1	K369S	Pathogenic	0.792
SLC26A4	O43511-1.1	K369T	Pathogenic	0.944
SLC26A4	O43511-1.1	K369V	Pathogenic	0.976
SLC26A4	O43511-1.1	K369W	Pathogenic	0.983
SLC26A4	O43511-1.1	K369Y	Pathogenic	0.992
SLC26A4	O43511-1.1	V370A	Pathogenic	0.925
SLC26A4	O43511-1.1	V370C	Pathogenic	0.987
SLC26A4	O43511-1.1	V370D	Pathogenic	0.995
SLC26A4	O43511-1.1	V370E	Pathogenic	0.994
SLC26A4	O43511-1.1	V370F	Pathogenic	0.976
SLC26A4	O43511-1.1	V370G	Pathogenic	0.974
SLC26A4	O43511-1.1	V370H	Pathogenic	0.997
SLC26A4	O43511-1.1	V370I	Pathogenic	0.803
SLC26A4	O43511-1.1	V370K	Pathogenic	0.978
SLC26A4	O43511-1.1	V370L	Pathogenic	0.945
SLC26A4	O43511-1.1	V370M	Pathogenic	0.954
SLC26A4	O43511-1.1	V370N	Pathogenic	0.996
SLC26A4	O43511-1.1	V370P	Pathogenic	0.994
SLC26A4	O43511-1.1	V370Q	Pathogenic	0.993
SLC26A4	O43511-1.1	V370R	Pathogenic	0.98
SLC26A4	O43511-1.1	V370S	Pathogenic	0.983
SLC26A4	O43511-1.1	V370T	Pathogenic	0.975
SLC26A4	O43511-1.1	V370W	Pathogenic	0.975
SLC26A4	O43511-1.1	V370Y	Pathogenic	0.972
SLC26A4	O43511-1.1	Y371A	Pathogenic	0.99
SLC26A4	O43511-1.1	Y371C	Pathogenic	0.997
SLC26A4	O43511-1.1	Y371D	Pathogenic	0.997
SLC26A4	O43511-1.1	Y371E	Pathogenic	0.998
SLC26A4	O43511-1.1	Y371F	Pathogenic	0.983
SLC26A4	O43511-1.1	Y371G	Pathogenic	0.986
SLC26A4	O43511-1.1	Y371H	Pathogenic	0.982
SLC26A4	O43511-1.1	Y371I	Pathogenic	0.998
SLC26A4	O43511-1.1	Y371K	Pathogenic	0.999
SLC26A4	O43511-1.1	Y371L	Pathogenic	0.998
SLC26A4	O43511-1.1	Y371M	Pathogenic	0.999
SLC26A4	O43511-1.1	Y371N	Pathogenic	0.996
SLC26A4	O43511-1.1	Y371P	Pathogenic	0.998
SLC26A4	O43511-1.1	Y371Q	Pathogenic	0.997
SLC26A4	O43511-1.1	Y371R	Pathogenic	0.999
SLC26A4	O43511-1.1	Y371S	Pathogenic	0.991
SLC26A4	O43511-1.1	Y371T	Pathogenic	0.997
SLC26A4	O43511-1.1	Y371V	Pathogenic	0.997
SLC26A4	O43511-1.1	Y371W	Pathogenic	0.98
SLC26A4	O43511-1.1	A372C	Pathogenic	0.838
SLC26A4	O43511-1.1	A372D	Pathogenic	0.935
SLC26A4	O43511-1.1	A372E	Pathogenic	0.769
SLC26A4	O43511-1.1	A372F	Pathogenic	0.627
SLC26A4	O43511-1.1	A372G	Pathogenic	0.857
SLC26A4	O43511-1.1	A372H	Pathogenic	0.857
SLC26A4	O43511-1.1	A372I	Pathogenic	0.578
SLC26A4	O43511-1.1	A372K	Neutral	0.473
SLC26A4	O43511-1.1	A372L	Pathogenic	0.587
SLC26A4	O43511-1.1	A372M	Pathogenic	0.63
SLC26A4	O43511-1.1	A372N	Pathogenic	0.924
SLC26A4	O43511-1.1	A372P	Pathogenic	0.906
SLC26A4	O43511-1.1	A372Q	Pathogenic	0.757
SLC26A4	O43511-1.1	A372R	Neutral	0.332
SLC26A4	O43511-1.1	A372S	Pathogenic	0.841
SLC26A4	O43511-1.1	A372T	Pathogenic	0.828
SLC26A4	O43511-1.1	A372V	Pathogenic	0.668
SLC26A4	O43511-1.1	A372W	Neutral	0.444
SLC26A4	O43511-1.1	A372Y	Pathogenic	0.638
SLC26A4	O43511-1.1	T373A	Neutral	0.349
SLC26A4	O43511-1.1	T373C	Pathogenic	0.662
SLC26A4	O43511-1.1	T373D	Pathogenic	0.686
SLC26A4	O43511-1.1	T373E	Pathogenic	0.55
SLC26A4	O43511-1.1	T373F	Neutral	0.373
SLC26A4	O43511-1.1	T373G	Neutral	0.459
SLC26A4	O43511-1.1	T373H	Pathogenic	0.688
SLC26A4	O43511-1.1	T373I	Neutral	0.326
SLC26A4	O43511-1.1	T373K	Neutral	0.248
SLC26A4	O43511-1.1	T373L	Neutral	0.334
SLC26A4	O43511-1.1	T373M	Neutral	0.376
SLC26A4	O43511-1.1	T373N	Pathogenic	0.526
SLC26A4	O43511-1.1	T373P	Pathogenic	0.722
SLC26A4	O43511-1.1	T373Q	Pathogenic	0.534
SLC26A4	O43511-1.1	T373R	Neutral	0.154
SLC26A4	O43511-1.1	T373S	Neutral	0.242
SLC26A4	O43511-1.1	T373V	Neutral	0.415
SLC26A4	O43511-1.1	T373W	Neutral	0.123
SLC26A4	O43511-1.1	T373Y	Neutral	0.384
SLC26A4	O43511-1.1	K374A	Pathogenic	0.963
SLC26A4	O43511-1.1	K374C	Pathogenic	0.995
SLC26A4	O43511-1.1	K374D	Pathogenic	0.992
SLC26A4	O43511-1.1	K374E	Pathogenic	0.984
SLC26A4	O43511-1.1	K374F	Pathogenic	0.999
SLC26A4	O43511-1.1	K374G	Pathogenic	0.962
SLC26A4	O43511-1.1	K374H	Pathogenic	0.996
SLC26A4	O43511-1.1	K374I	Pathogenic	0.999
SLC26A4	O43511-1.1	K374L	Pathogenic	0.998
SLC26A4	O43511-1.1	K374M	Pathogenic	0.996
SLC26A4	O43511-1.1	K374N	Pathogenic	0.986
SLC26A4	O43511-1.1	K374P	Pathogenic	0.985
SLC26A4	O43511-1.1	K374Q	Pathogenic	0.985
SLC26A4	O43511-1.1	K374R	Pathogenic	0.985
SLC26A4	O43511-1.1	K374S	Pathogenic	0.952
SLC26A4	O43511-1.1	K374T	Pathogenic	0.989
SLC26A4	O43511-1.1	K374V	Pathogenic	0.995
SLC26A4	O43511-1.1	K374W	Pathogenic	0.997
SLC26A4	O43511-1.1	K374Y	Pathogenic	0.999
SLC26A4	O43511-1.1	Y375A	Pathogenic	0.902
SLC26A4	O43511-1.1	Y375C	Pathogenic	0.965
SLC26A4	O43511-1.1	Y375D	Pathogenic	0.973
SLC26A4	O43511-1.1	Y375E	Pathogenic	0.977
SLC26A4	O43511-1.1	Y375F	Pathogenic	0.849
SLC26A4	O43511-1.1	Y375G	Pathogenic	0.874
SLC26A4	O43511-1.1	Y375H	Pathogenic	0.84
SLC26A4	O43511-1.1	Y375I	Pathogenic	0.982
SLC26A4	O43511-1.1	Y375K	Pathogenic	0.992
SLC26A4	O43511-1.1	Y375L	Pathogenic	0.983
SLC26A4	O43511-1.1	Y375M	Pathogenic	0.986
SLC26A4	O43511-1.1	Y375N	Pathogenic	0.96
SLC26A4	O43511-1.1	Y375P	Pathogenic	0.984
SLC26A4	O43511-1.1	Y375Q	Pathogenic	0.969
SLC26A4	O43511-1.1	Y375R	Pathogenic	0.991
SLC26A4	O43511-1.1	Y375S	Pathogenic	0.913
SLC26A4	O43511-1.1	Y375T	Pathogenic	0.967
SLC26A4	O43511-1.1	Y375V	Pathogenic	0.967
SLC26A4	O43511-1.1	Y375W	Pathogenic	0.821
SLC26A4	O43511-1.1	D376A	Pathogenic	0.996
SLC26A4	O43511-1.1	D376C	Pathogenic	0.999
SLC26A4	O43511-1.1	D376E	Pathogenic	0.964
SLC26A4	O43511-1.1	D376F	Pathogenic	0.991
SLC26A4	O43511-1.1	D376G	Pathogenic	0.982
SLC26A4	O43511-1.1	D376H	Pathogenic	0.991
SLC26A4	O43511-1.1	D376I	Pathogenic	0.994
SLC26A4	O43511-1.1	D376K	Pathogenic	0.985
SLC26A4	O43511-1.1	D376L	Pathogenic	0.997
SLC26A4	O43511-1.1	D376M	Pathogenic	0.995
SLC26A4	O43511-1.1	D376N	Pathogenic	0.989
SLC26A4	O43511-1.1	D376P	Pathogenic	0.996
SLC26A4	O43511-1.1	D376Q	Pathogenic	0.986
SLC26A4	O43511-1.1	D376R	Pathogenic	0.986
SLC26A4	O43511-1.1	D376S	Pathogenic	0.988
SLC26A4	O43511-1.1	D376T	Pathogenic	0.997
SLC26A4	O43511-1.1	D376V	Pathogenic	0.998
SLC26A4	O43511-1.1	D376W	Pathogenic	0.98
SLC26A4	O43511-1.1	D376Y	Pathogenic	0.991
SLC26A4	O43511-1.1	Y377A	Pathogenic	0.996
SLC26A4	O43511-1.1	Y377C	Pathogenic	0.999
SLC26A4	O43511-1.1	Y377D	Pathogenic	0.999
SLC26A4	O43511-1.1	Y377E	Pathogenic	0.999
SLC26A4	O43511-1.1	Y377F	Pathogenic	0.994
SLC26A4	O43511-1.1	Y377G	Pathogenic	0.995
SLC26A4	O43511-1.1	Y377H	Pathogenic	0.993
SLC26A4	O43511-1.1	Y377I	Pathogenic	0.999
SLC26A4	O43511-1.1	Y377K	Pathogenic	1.0
SLC26A4	O43511-1.1	Y377L	Pathogenic	0.999
SLC26A4	O43511-1.1	Y377M	Pathogenic	0.999
SLC26A4	O43511-1.1	Y377N	Pathogenic	0.999
SLC26A4	O43511-1.1	Y377P	Pathogenic	0.999
SLC26A4	O43511-1.1	Y377Q	Pathogenic	0.999
SLC26A4	O43511-1.1	Y377R	Pathogenic	1.0
SLC26A4	O43511-1.1	Y377S	Pathogenic	0.997
SLC26A4	O43511-1.1	Y377T	Pathogenic	0.999
SLC26A4	O43511-1.1	Y377V	Pathogenic	0.999
SLC26A4	O43511-1.1	Y377W	Pathogenic	0.992
SLC26A4	O43511-1.1	T378A	Neutral	0.288
SLC26A4	O43511-1.1	T378C	Pathogenic	0.597
SLC26A4	O43511-1.1	T378D	Pathogenic	0.623
SLC26A4	O43511-1.1	T378E	Neutral	0.48
SLC26A4	O43511-1.1	T378F	Neutral	0.31
SLC26A4	O43511-1.1	T378G	Neutral	0.391
SLC26A4	O43511-1.1	T378H	Pathogenic	0.625
SLC26A4	O43511-1.1	T378I	Neutral	0.268
SLC26A4	O43511-1.1	T378K	Neutral	0.2
SLC26A4	O43511-1.1	T378L	Neutral	0.275
SLC26A4	O43511-1.1	T378M	Neutral	0.313
SLC26A4	O43511-1.1	T378N	Neutral	0.456
SLC26A4	O43511-1.1	T378P	Pathogenic	0.663
SLC26A4	O43511-1.1	T378Q	Neutral	0.464
SLC26A4	O43511-1.1	T378R	Neutral	0.121
SLC26A4	O43511-1.1	T378S	Neutral	0.194
SLC26A4	O43511-1.1	T378V	Neutral	0.35
SLC26A4	O43511-1.1	T378W	Neutral	0.096
SLC26A4	O43511-1.1	T378Y	Neutral	0.32
SLC26A4	O43511-1.1	I379A	Pathogenic	0.745
SLC26A4	O43511-1.1	I379C	Pathogenic	0.899
SLC26A4	O43511-1.1	I379D	Pathogenic	0.958
SLC26A4	O43511-1.1	I379E	Pathogenic	0.982
SLC26A4	O43511-1.1	I379F	Pathogenic	0.954
SLC26A4	O43511-1.1	I379G	Pathogenic	0.899
SLC26A4	O43511-1.1	I379H	Pathogenic	0.991
SLC26A4	O43511-1.1	I379K	Pathogenic	0.983
SLC26A4	O43511-1.1	I379L	Pathogenic	0.89
SLC26A4	O43511-1.1	I379M	Pathogenic	0.931
SLC26A4	O43511-1.1	I379N	Pathogenic	0.969
SLC26A4	O43511-1.1	I379P	Pathogenic	0.975
SLC26A4	O43511-1.1	I379Q	Pathogenic	0.988
SLC26A4	O43511-1.1	I379R	Pathogenic	0.969
SLC26A4	O43511-1.1	I379S	Pathogenic	0.871
SLC26A4	O43511-1.1	I379T	Pathogenic	0.903
SLC26A4	O43511-1.1	I379V	Pathogenic	0.586
SLC26A4	O43511-1.1	I379W	Pathogenic	0.976
SLC26A4	O43511-1.1	I379Y	Pathogenic	0.958
SLC26A4	O43511-1.1	D380A	Pathogenic	0.997
SLC26A4	O43511-1.1	D380C	Pathogenic	0.999
SLC26A4	O43511-1.1	D380E	Pathogenic	0.979
SLC26A4	O43511-1.1	D380F	Pathogenic	0.995
SLC26A4	O43511-1.1	D380G	Pathogenic	0.989
SLC26A4	O43511-1.1	D380H	Pathogenic	0.995
SLC26A4	O43511-1.1	D380I	Pathogenic	0.997
SLC26A4	O43511-1.1	D380K	Pathogenic	0.991
SLC26A4	O43511-1.1	D380L	Pathogenic	0.998
SLC26A4	O43511-1.1	D380M	Pathogenic	0.997
SLC26A4	O43511-1.1	D380N	Pathogenic	0.994
SLC26A4	O43511-1.1	D380P	Pathogenic	0.998
SLC26A4	O43511-1.1	D380Q	Pathogenic	0.992
SLC26A4	O43511-1.1	D380R	Pathogenic	0.992
SLC26A4	O43511-1.1	D380S	Pathogenic	0.993
SLC26A4	O43511-1.1	D380T	Pathogenic	0.998
SLC26A4	O43511-1.1	D380V	Pathogenic	0.999
SLC26A4	O43511-1.1	D380W	Pathogenic	0.989
SLC26A4	O43511-1.1	D380Y	Pathogenic	0.995
SLC26A4	O43511-1.1	G381A	Pathogenic	0.992
SLC26A4	O43511-1.1	G381C	Pathogenic	0.997
SLC26A4	O43511-1.1	G381D	Pathogenic	0.986
SLC26A4	O43511-1.1	G381E	Pathogenic	0.985
SLC26A4	O43511-1.1	G381F	Pathogenic	0.963
SLC26A4	O43511-1.1	G381H	Pathogenic	0.981
SLC26A4	O43511-1.1	G381I	Pathogenic	0.988
SLC26A4	O43511-1.1	G381K	Pathogenic	0.946
SLC26A4	O43511-1.1	G381L	Pathogenic	0.989
SLC26A4	O43511-1.1	G381M	Pathogenic	0.982
SLC26A4	O43511-1.1	G381N	Pathogenic	0.967
SLC26A4	O43511-1.1	G381P	Pathogenic	0.993
SLC26A4	O43511-1.1	G381Q	Pathogenic	0.984
SLC26A4	O43511-1.1	G381R	Pathogenic	0.907
SLC26A4	O43511-1.1	G381S	Pathogenic	0.99
SLC26A4	O43511-1.1	G381T	Pathogenic	0.994
SLC26A4	O43511-1.1	G381V	Pathogenic	0.992
SLC26A4	O43511-1.1	G381W	Pathogenic	0.754
SLC26A4	O43511-1.1	G381Y	Pathogenic	0.965
SLC26A4	O43511-1.1	N382A	Pathogenic	0.999
SLC26A4	O43511-1.1	N382C	Pathogenic	1.0
SLC26A4	O43511-1.1	N382D	Pathogenic	0.998
SLC26A4	O43511-1.1	N382E	Pathogenic	0.998
SLC26A4	O43511-1.1	N382F	Pathogenic	0.998
SLC26A4	O43511-1.1	N382G	Pathogenic	0.991
SLC26A4	O43511-1.1	N382H	Pathogenic	0.994
SLC26A4	O43511-1.1	N382I	Pathogenic	0.999
SLC26A4	O43511-1.1	N382K	Pathogenic	0.994
SLC26A4	O43511-1.1	N382L	Pathogenic	0.999
SLC26A4	O43511-1.1	N382M	Pathogenic	0.998
SLC26A4	O43511-1.1	N382P	Pathogenic	1.0
SLC26A4	O43511-1.1	N382Q	Pathogenic	0.998
SLC26A4	O43511-1.1	N382R	Pathogenic	0.99
SLC26A4	O43511-1.1	N382S	Pathogenic	0.994
SLC26A4	O43511-1.1	N382T	Pathogenic	0.999
SLC26A4	O43511-1.1	N382V	Pathogenic	1.0
SLC26A4	O43511-1.1	N382W	Pathogenic	0.997
SLC26A4	O43511-1.1	N382Y	Pathogenic	0.997
SLC26A4	O43511-1.1	Q383A	Pathogenic	0.997
SLC26A4	O43511-1.1	Q383C	Pathogenic	1.0
SLC26A4	O43511-1.1	Q383D	Pathogenic	0.998
SLC26A4	O43511-1.1	Q383E	Pathogenic	0.996
SLC26A4	O43511-1.1	Q383F	Pathogenic	1.0
SLC26A4	O43511-1.1	Q383G	Pathogenic	0.997
SLC26A4	O43511-1.1	Q383H	Pathogenic	0.999
SLC26A4	O43511-1.1	Q383I	Pathogenic	1.0
SLC26A4	O43511-1.1	Q383K	Pathogenic	0.996
SLC26A4	O43511-1.1	Q383L	Pathogenic	1.0
SLC26A4	O43511-1.1	Q383M	Pathogenic	0.998
SLC26A4	O43511-1.1	Q383N	Pathogenic	0.998
SLC26A4	O43511-1.1	Q383P	Pathogenic	0.999
SLC26A4	O43511-1.1	Q383R	Pathogenic	0.992
SLC26A4	O43511-1.1	Q383S	Pathogenic	0.996
SLC26A4	O43511-1.1	Q383T	Pathogenic	0.999
SLC26A4	O43511-1.1	Q383V	Pathogenic	1.0
SLC26A4	O43511-1.1	Q383W	Pathogenic	0.996
SLC26A4	O43511-1.1	Q383Y	Pathogenic	0.998
SLC26A4	O43511-1.1	E384A	Pathogenic	0.994
SLC26A4	O43511-1.1	E384C	Pathogenic	1.0
SLC26A4	O43511-1.1	E384D	Pathogenic	0.989
SLC26A4	O43511-1.1	E384F	Pathogenic	0.999
SLC26A4	O43511-1.1	E384G	Pathogenic	0.994
SLC26A4	O43511-1.1	E384H	Pathogenic	0.998
SLC26A4	O43511-1.1	E384I	Pathogenic	0.999
SLC26A4	O43511-1.1	E384K	Pathogenic	0.991
SLC26A4	O43511-1.1	E384L	Pathogenic	0.999
SLC26A4	O43511-1.1	E384M	Pathogenic	0.999
SLC26A4	O43511-1.1	E384N	Pathogenic	0.998
SLC26A4	O43511-1.1	E384P	Pathogenic	0.998
SLC26A4	O43511-1.1	E384Q	Pathogenic	0.993
SLC26A4	O43511-1.1	E384R	Pathogenic	0.992
SLC26A4	O43511-1.1	E384S	Pathogenic	0.992
SLC26A4	O43511-1.1	E384T	Pathogenic	0.998
SLC26A4	O43511-1.1	E384V	Pathogenic	0.999
SLC26A4	O43511-1.1	E384W	Pathogenic	0.995
SLC26A4	O43511-1.1	E384Y	Pathogenic	0.998
SLC26A4	O43511-1.1	F385A	Pathogenic	0.57
SLC26A4	O43511-1.1	F385C	Pathogenic	0.802
SLC26A4	O43511-1.1	F385D	Pathogenic	0.839
SLC26A4	O43511-1.1	F385E	Pathogenic	0.925
SLC26A4	O43511-1.1	F385G	Pathogenic	0.501
SLC26A4	O43511-1.1	F385H	Pathogenic	0.86
SLC26A4	O43511-1.1	F385I	Pathogenic	0.883
SLC26A4	O43511-1.1	F385K	Pathogenic	0.972
SLC26A4	O43511-1.1	F385L	Pathogenic	0.88
SLC26A4	O43511-1.1	F385M	Pathogenic	0.86
SLC26A4	O43511-1.1	F385N	Pathogenic	0.874
SLC26A4	O43511-1.1	F385P	Pathogenic	0.947
SLC26A4	O43511-1.1	F385Q	Pathogenic	0.948
SLC26A4	O43511-1.1	F385R	Pathogenic	0.951
SLC26A4	O43511-1.1	F385S	Pathogenic	0.603
SLC26A4	O43511-1.1	F385T	Pathogenic	0.808
SLC26A4	O43511-1.1	F385V	Pathogenic	0.839
SLC26A4	O43511-1.1	F385W	Pathogenic	0.596
SLC26A4	O43511-1.1	F385Y	Neutral	0.461
SLC26A4	O43511-1.1	I386A	Pathogenic	0.866
SLC26A4	O43511-1.1	I386C	Pathogenic	0.952
SLC26A4	O43511-1.1	I386D	Pathogenic	0.981
SLC26A4	O43511-1.1	I386E	Pathogenic	0.992
SLC26A4	O43511-1.1	I386F	Pathogenic	0.978
SLC26A4	O43511-1.1	I386G	Pathogenic	0.952
SLC26A4	O43511-1.1	I386H	Pathogenic	0.996
SLC26A4	O43511-1.1	I386K	Pathogenic	0.992
SLC26A4	O43511-1.1	I386L	Pathogenic	0.947
SLC26A4	O43511-1.1	I386M	Pathogenic	0.968
SLC26A4	O43511-1.1	I386N	Pathogenic	0.985
SLC26A4	O43511-1.1	I386P	Pathogenic	0.989
SLC26A4	O43511-1.1	I386Q	Pathogenic	0.994
SLC26A4	O43511-1.1	I386R	Pathogenic	0.986
SLC26A4	O43511-1.1	I386S	Pathogenic	0.937
SLC26A4	O43511-1.1	I386T	Pathogenic	0.953
SLC26A4	O43511-1.1	I386V	Pathogenic	0.757
SLC26A4	O43511-1.1	I386W	Pathogenic	0.989
SLC26A4	O43511-1.1	I386Y	Pathogenic	0.981
SLC26A4	O43511-1.1	A387C	Pathogenic	0.99
SLC26A4	O43511-1.1	A387D	Pathogenic	0.996
SLC26A4	O43511-1.1	A387E	Pathogenic	0.984
SLC26A4	O43511-1.1	A387F	Pathogenic	0.968
SLC26A4	O43511-1.1	A387G	Pathogenic	0.991
SLC26A4	O43511-1.1	A387H	Pathogenic	0.991
SLC26A4	O43511-1.1	A387I	Pathogenic	0.961
SLC26A4	O43511-1.1	A387K	Pathogenic	0.942
SLC26A4	O43511-1.1	A387L	Pathogenic	0.963
SLC26A4	O43511-1.1	A387M	Pathogenic	0.969
SLC26A4	O43511-1.1	A387N	Pathogenic	0.996
SLC26A4	O43511-1.1	A387P	Pathogenic	0.994
SLC26A4	O43511-1.1	A387Q	Pathogenic	0.983
SLC26A4	O43511-1.1	A387R	Pathogenic	0.9
SLC26A4	O43511-1.1	A387S	Pathogenic	0.99
SLC26A4	O43511-1.1	A387T	Pathogenic	0.989
SLC26A4	O43511-1.1	A387V	Pathogenic	0.973
SLC26A4	O43511-1.1	A387W	Pathogenic	0.936
SLC26A4	O43511-1.1	A387Y	Pathogenic	0.97
SLC26A4	O43511-1.1	F388A	Pathogenic	0.769
SLC26A4	O43511-1.1	F388C	Pathogenic	0.91
SLC26A4	O43511-1.1	F388D	Pathogenic	0.929
SLC26A4	O43511-1.1	F388E	Pathogenic	0.969
SLC26A4	O43511-1.1	F388G	Pathogenic	0.715
SLC26A4	O43511-1.1	F388H	Pathogenic	0.939
SLC26A4	O43511-1.1	F388I	Pathogenic	0.95
SLC26A4	O43511-1.1	F388K	Pathogenic	0.989
SLC26A4	O43511-1.1	F388L	Pathogenic	0.949
SLC26A4	O43511-1.1	F388M	Pathogenic	0.939
SLC26A4	O43511-1.1	F388N	Pathogenic	0.946
SLC26A4	O43511-1.1	F388P	Pathogenic	0.978
SLC26A4	O43511-1.1	F388Q	Pathogenic	0.978
SLC26A4	O43511-1.1	F388R	Pathogenic	0.98
SLC26A4	O43511-1.1	F388S	Pathogenic	0.792
SLC26A4	O43511-1.1	F388T	Pathogenic	0.913
SLC26A4	O43511-1.1	F388V	Pathogenic	0.929
SLC26A4	O43511-1.1	F388W	Pathogenic	0.787
SLC26A4	O43511-1.1	F388Y	Pathogenic	0.682
SLC26A4	O43511-1.1	G389A	Pathogenic	0.993
SLC26A4	O43511-1.1	G389C	Pathogenic	0.997
SLC26A4	O43511-1.1	G389D	Pathogenic	0.988
SLC26A4	O43511-1.1	G389E	Pathogenic	0.987
SLC26A4	O43511-1.1	G389F	Pathogenic	0.968
SLC26A4	O43511-1.1	G389H	Pathogenic	0.984
SLC26A4	O43511-1.1	G389I	Pathogenic	0.99
SLC26A4	O43511-1.1	G389K	Pathogenic	0.953
SLC26A4	O43511-1.1	G389L	Pathogenic	0.99
SLC26A4	O43511-1.1	G389M	Pathogenic	0.984
SLC26A4	O43511-1.1	G389N	Pathogenic	0.971
SLC26A4	O43511-1.1	G389P	Pathogenic	0.994
SLC26A4	O43511-1.1	G389Q	Pathogenic	0.986
SLC26A4	O43511-1.1	G389R	Pathogenic	0.918
SLC26A4	O43511-1.1	G389S	Pathogenic	0.992
SLC26A4	O43511-1.1	G389T	Pathogenic	0.994
SLC26A4	O43511-1.1	G389V	Pathogenic	0.993
SLC26A4	O43511-1.1	G389W	Pathogenic	0.778
SLC26A4	O43511-1.1	G389Y	Pathogenic	0.969
SLC26A4	O43511-1.1	I390A	Neutral	0.107
SLC26A4	O43511-1.1	I390C	Neutral	0.268
SLC26A4	O43511-1.1	I390D	Neutral	0.485
SLC26A4	O43511-1.1	I390E	Pathogenic	0.691
SLC26A4	O43511-1.1	I390F	Neutral	0.456
SLC26A4	O43511-1.1	I390G	Neutral	0.267
SLC26A4	O43511-1.1	I390H	Pathogenic	0.818
SLC26A4	O43511-1.1	I390K	Pathogenic	0.7
SLC26A4	O43511-1.1	I390L	Neutral	0.248
SLC26A4	O43511-1.1	I390M	Neutral	0.357
SLC26A4	O43511-1.1	I390N	Pathogenic	0.557
SLC26A4	O43511-1.1	I390P	Pathogenic	0.615
SLC26A4	O43511-1.1	I390Q	Pathogenic	0.767
SLC26A4	O43511-1.1	I390R	Pathogenic	0.563
SLC26A4	O43511-1.1	I390S	Neutral	0.216
SLC26A4	O43511-1.1	I390T	Neutral	0.275
SLC26A4	O43511-1.1	I390V	Neutral	0.055
SLC26A4	O43511-1.1	I390W	Pathogenic	0.62
SLC26A4	O43511-1.1	I390Y	Neutral	0.483
SLC26A4	O43511-1.1	S391A	Pathogenic	0.829
SLC26A4	O43511-1.1	S391C	Pathogenic	0.916
SLC26A4	O43511-1.1	S391D	Pathogenic	0.829
SLC26A4	O43511-1.1	S391E	Pathogenic	0.694
SLC26A4	O43511-1.1	S391F	Pathogenic	0.639
SLC26A4	O43511-1.1	S391G	Pathogenic	0.823
SLC26A4	O43511-1.1	S391H	Pathogenic	0.782
SLC26A4	O43511-1.1	S391I	Pathogenic	0.743
SLC26A4	O43511-1.1	S391K	Neutral	0.38
SLC26A4	O43511-1.1	S391L	Pathogenic	0.75
SLC26A4	O43511-1.1	S391M	Pathogenic	0.642
SLC26A4	O43511-1.1	S391N	Pathogenic	0.673
SLC26A4	O43511-1.1	S391P	Pathogenic	0.91
SLC26A4	O43511-1.1	S391Q	Pathogenic	0.68
SLC26A4	O43511-1.1	S391R	Neutral	0.405
SLC26A4	O43511-1.1	S391T	Pathogenic	0.724
SLC26A4	O43511-1.1	S391V	Pathogenic	0.895
SLC26A4	O43511-1.1	S391W	Neutral	0.457
SLC26A4	O43511-1.1	S391Y	Pathogenic	0.65
SLC26A4	O43511-1.1	N392A	Pathogenic	0.999
SLC26A4	O43511-1.1	N392C	Pathogenic	1.0
SLC26A4	O43511-1.1	N392D	Pathogenic	0.997
SLC26A4	O43511-1.1	N392E	Pathogenic	0.998
SLC26A4	O43511-1.1	N392F	Pathogenic	0.998
SLC26A4	O43511-1.1	N392G	Pathogenic	0.99
SLC26A4	O43511-1.1	N392H	Pathogenic	0.993
SLC26A4	O43511-1.1	N392I	Pathogenic	0.999
SLC26A4	O43511-1.1	N392K	Pathogenic	0.994
SLC26A4	O43511-1.1	N392L	Pathogenic	0.999
SLC26A4	O43511-1.1	N392M	Pathogenic	0.998
SLC26A4	O43511-1.1	N392P	Pathogenic	0.999
SLC26A4	O43511-1.1	N392Q	Pathogenic	0.998
SLC26A4	O43511-1.1	N392R	Pathogenic	0.989
SLC26A4	O43511-1.1	N392S	Pathogenic	0.993
SLC26A4	O43511-1.1	N392T	Pathogenic	0.999
SLC26A4	O43511-1.1	N392V	Pathogenic	1.0
SLC26A4	O43511-1.1	N392W	Pathogenic	0.996
SLC26A4	O43511-1.1	N392Y	Pathogenic	0.997
SLC26A4	O43511-1.1	I393A	Pathogenic	0.688
SLC26A4	O43511-1.1	I393C	Pathogenic	0.871
SLC26A4	O43511-1.1	I393D	Pathogenic	0.946
SLC26A4	O43511-1.1	I393E	Pathogenic	0.976
SLC26A4	O43511-1.1	I393F	Pathogenic	0.939
SLC26A4	O43511-1.1	I393G	Pathogenic	0.871
SLC26A4	O43511-1.1	I393H	Pathogenic	0.988
SLC26A4	O43511-1.1	I393K	Pathogenic	0.977
SLC26A4	O43511-1.1	I393L	Pathogenic	0.859
SLC26A4	O43511-1.1	I393M	Pathogenic	0.911
SLC26A4	O43511-1.1	I393N	Pathogenic	0.959
SLC26A4	O43511-1.1	I393P	Pathogenic	0.967
SLC26A4	O43511-1.1	I393Q	Pathogenic	0.984
SLC26A4	O43511-1.1	I393R	Pathogenic	0.96
SLC26A4	O43511-1.1	I393S	Pathogenic	0.836
SLC26A4	O43511-1.1	I393T	Pathogenic	0.875
SLC26A4	O43511-1.1	I393V	Pathogenic	0.517
SLC26A4	O43511-1.1	I393W	Pathogenic	0.968
SLC26A4	O43511-1.1	I393Y	Pathogenic	0.945
SLC26A4	O43511-1.1	F394A	Pathogenic	0.679
SLC26A4	O43511-1.1	F394C	Pathogenic	0.866
SLC26A4	O43511-1.1	F394D	Pathogenic	0.893
SLC26A4	O43511-1.1	F394E	Pathogenic	0.952
SLC26A4	O43511-1.1	F394G	Pathogenic	0.616
SLC26A4	O43511-1.1	F394H	Pathogenic	0.908
SLC26A4	O43511-1.1	F394I	Pathogenic	0.924
SLC26A4	O43511-1.1	F394K	Pathogenic	0.982
SLC26A4	O43511-1.1	F394L	Pathogenic	0.922
SLC26A4	O43511-1.1	F394M	Pathogenic	0.908
SLC26A4	O43511-1.1	F394N	Pathogenic	0.917
SLC26A4	O43511-1.1	F394P	Pathogenic	0.966
SLC26A4	O43511-1.1	F394Q	Pathogenic	0.967
SLC26A4	O43511-1.1	F394R	Pathogenic	0.968
SLC26A4	O43511-1.1	F394S	Pathogenic	0.709
SLC26A4	O43511-1.1	F394T	Pathogenic	0.87
SLC26A4	O43511-1.1	F394V	Pathogenic	0.893
SLC26A4	O43511-1.1	F394W	Pathogenic	0.702
SLC26A4	O43511-1.1	F394Y	Pathogenic	0.578
SLC26A4	O43511-1.1	S395A	Neutral	0.446
SLC26A4	O43511-1.1	S395C	Pathogenic	0.646
SLC26A4	O43511-1.1	S395D	Neutral	0.447
SLC26A4	O43511-1.1	S395E	Neutral	0.274
SLC26A4	O43511-1.1	S395F	Neutral	0.227
SLC26A4	O43511-1.1	S395G	Neutral	0.436
SLC26A4	O43511-1.1	S395H	Neutral	0.374
SLC26A4	O43511-1.1	S395I	Neutral	0.325
SLC26A4	O43511-1.1	S395K	Neutral	0.093
SLC26A4	O43511-1.1	S395L	Neutral	0.333
SLC26A4	O43511-1.1	S395M	Neutral	0.23
SLC26A4	O43511-1.1	S395N	Neutral	0.256
SLC26A4	O43511-1.1	S395P	Pathogenic	0.628
SLC26A4	O43511-1.1	S395Q	Neutral	0.262
SLC26A4	O43511-1.1	S395R	Neutral	0.102
SLC26A4	O43511-1.1	S395T	Neutral	0.304
SLC26A4	O43511-1.1	S395V	Pathogenic	0.587
SLC26A4	O43511-1.1	S395W	Neutral	0.123
SLC26A4	O43511-1.1	S395Y	Neutral	0.236
SLC26A4	O43511-1.1	G396A	Pathogenic	0.961
SLC26A4	O43511-1.1	G396C	Pathogenic	0.985
SLC26A4	O43511-1.1	G396D	Pathogenic	0.933
SLC26A4	O43511-1.1	G396E	Pathogenic	0.929
SLC26A4	O43511-1.1	G396F	Pathogenic	0.839
SLC26A4	O43511-1.1	G396H	Pathogenic	0.914
SLC26A4	O43511-1.1	G396I	Pathogenic	0.945
SLC26A4	O43511-1.1	G396K	Pathogenic	0.78
SLC26A4	O43511-1.1	G396L	Pathogenic	0.947
SLC26A4	O43511-1.1	G396M	Pathogenic	0.914
SLC26A4	O43511-1.1	G396N	Pathogenic	0.855
SLC26A4	O43511-1.1	G396P	Pathogenic	0.968
SLC26A4	O43511-1.1	G396Q	Pathogenic	0.925
SLC26A4	O43511-1.1	G396R	Pathogenic	0.662
SLC26A4	O43511-1.1	G396S	Pathogenic	0.954
SLC26A4	O43511-1.1	G396T	Pathogenic	0.969
SLC26A4	O43511-1.1	G396V	Pathogenic	0.962
SLC26A4	O43511-1.1	G396W	Neutral	0.381
SLC26A4	O43511-1.1	G396Y	Pathogenic	0.846
SLC26A4	O43511-1.1	F397A	Neutral	0.088
SLC26A4	O43511-1.1	F397C	Neutral	0.228
SLC26A4	O43511-1.1	F397D	Neutral	0.275
SLC26A4	O43511-1.1	F397E	Neutral	0.473
SLC26A4	O43511-1.1	F397G	Neutral	0.068
SLC26A4	O43511-1.1	F397H	Neutral	0.31
SLC26A4	O43511-1.1	F397I	Neutral	0.356
SLC26A4	O43511-1.1	F397K	Pathogenic	0.717
SLC26A4	O43511-1.1	F397L	Neutral	0.349
SLC26A4	O43511-1.1	F397M	Neutral	0.309
SLC26A4	O43511-1.1	F397N	Neutral	0.336
SLC26A4	O43511-1.1	F397P	Pathogenic	0.564
SLC26A4	O43511-1.1	F397Q	Pathogenic	0.569
SLC26A4	O43511-1.1	F397R	Pathogenic	0.584
SLC26A4	O43511-1.1	F397S	Neutral	0.1
SLC26A4	O43511-1.1	F397T	Neutral	0.235
SLC26A4	O43511-1.1	F397V	Neutral	0.275
SLC26A4	O43511-1.1	F397W	Neutral	0.097
SLC26A4	O43511-1.1	F397Y	Neutral	0.059
SLC26A4	O43511-1.1	F398A	Pathogenic	0.978
SLC26A4	O43511-1.1	F398C	Pathogenic	0.993
SLC26A4	O43511-1.1	F398D	Pathogenic	0.994
SLC26A4	O43511-1.1	F398E	Pathogenic	0.998
SLC26A4	O43511-1.1	F398G	Pathogenic	0.971
SLC26A4	O43511-1.1	F398H	Pathogenic	0.995
SLC26A4	O43511-1.1	F398I	Pathogenic	0.996
SLC26A4	O43511-1.1	F398K	Pathogenic	0.999
SLC26A4	O43511-1.1	F398L	Pathogenic	0.996
SLC26A4	O43511-1.1	F398M	Pathogenic	0.995
SLC26A4	O43511-1.1	F398N	Pathogenic	0.996
SLC26A4	O43511-1.1	F398P	Pathogenic	0.998
SLC26A4	O43511-1.1	F398Q	Pathogenic	0.998
SLC26A4	O43511-1.1	F398R	Pathogenic	0.998
SLC26A4	O43511-1.1	F398S	Pathogenic	0.981
SLC26A4	O43511-1.1	F398T	Pathogenic	0.993
SLC26A4	O43511-1.1	F398V	Pathogenic	0.994
SLC26A4	O43511-1.1	F398W	Pathogenic	0.98
SLC26A4	O43511-1.1	F398Y	Pathogenic	0.966
SLC26A4	O43511-1.1	S399A	Neutral	0.361
SLC26A4	O43511-1.1	S399C	Pathogenic	0.561
SLC26A4	O43511-1.1	S399D	Neutral	0.362
SLC26A4	O43511-1.1	S399E	Neutral	0.209
SLC26A4	O43511-1.1	S399F	Neutral	0.171
SLC26A4	O43511-1.1	S399G	Neutral	0.351
SLC26A4	O43511-1.1	S399H	Neutral	0.295
SLC26A4	O43511-1.1	S399I	Neutral	0.252
SLC26A4	O43511-1.1	S399K	Neutral	0.067
SLC26A4	O43511-1.1	S399L	Neutral	0.26
SLC26A4	O43511-1.1	S399M	Neutral	0.173
SLC26A4	O43511-1.1	S399N	Neutral	0.194
SLC26A4	O43511-1.1	S399P	Pathogenic	0.542
SLC26A4	O43511-1.1	S399Q	Neutral	0.199
SLC26A4	O43511-1.1	S399R	Neutral	0.074
SLC26A4	O43511-1.1	S399T	Neutral	0.234
SLC26A4	O43511-1.1	S399V	Neutral	0.499
SLC26A4	O43511-1.1	S399W	Neutral	0.089
SLC26A4	O43511-1.1	S399Y	Neutral	0.178
SLC26A4	O43511-1.1	C400A	Pathogenic	0.961
SLC26A4	O43511-1.1	C400D	Pathogenic	0.996
SLC26A4	O43511-1.1	C400E	Pathogenic	0.996
SLC26A4	O43511-1.1	C400F	Pathogenic	0.961
SLC26A4	O43511-1.1	C400G	Pathogenic	0.987
SLC26A4	O43511-1.1	C400H	Pathogenic	0.99
SLC26A4	O43511-1.1	C400I	Pathogenic	0.952
SLC26A4	O43511-1.1	C400K	Pathogenic	0.969
SLC26A4	O43511-1.1	C400L	Pathogenic	0.954
SLC26A4	O43511-1.1	C400M	Pathogenic	0.961
SLC26A4	O43511-1.1	C400N	Pathogenic	0.995
SLC26A4	O43511-1.1	C400P	Pathogenic	0.998
SLC26A4	O43511-1.1	C400Q	Pathogenic	0.991
SLC26A4	O43511-1.1	C400R	Pathogenic	0.945
SLC26A4	O43511-1.1	C400S	Pathogenic	0.983
SLC26A4	O43511-1.1	C400T	Pathogenic	0.988
SLC26A4	O43511-1.1	C400V	Pathogenic	0.983
SLC26A4	O43511-1.1	C400W	Pathogenic	0.853
SLC26A4	O43511-1.1	C400Y	Pathogenic	0.962
SLC26A4	O43511-1.1	F401A	Pathogenic	0.975
SLC26A4	O43511-1.1	F401C	Pathogenic	0.992
SLC26A4	O43511-1.1	F401D	Pathogenic	0.993
SLC26A4	O43511-1.1	F401E	Pathogenic	0.997
SLC26A4	O43511-1.1	F401G	Pathogenic	0.967
SLC26A4	O43511-1.1	F401H	Pathogenic	0.994
SLC26A4	O43511-1.1	F401I	Pathogenic	0.995
SLC26A4	O43511-1.1	F401K	Pathogenic	0.999
SLC26A4	O43511-1.1	F401L	Pathogenic	0.995
SLC26A4	O43511-1.1	F401M	Pathogenic	0.994
SLC26A4	O43511-1.1	F401N	Pathogenic	0.995
SLC26A4	O43511-1.1	F401P	Pathogenic	0.998
SLC26A4	O43511-1.1	F401Q	Pathogenic	0.998
SLC26A4	O43511-1.1	F401R	Pathogenic	0.998
SLC26A4	O43511-1.1	F401S	Pathogenic	0.978
SLC26A4	O43511-1.1	F401T	Pathogenic	0.992
SLC26A4	O43511-1.1	F401V	Pathogenic	0.993
SLC26A4	O43511-1.1	F401W	Pathogenic	0.977
SLC26A4	O43511-1.1	F401Y	Pathogenic	0.961
SLC26A4	O43511-1.1	V402A	Neutral	0.197
SLC26A4	O43511-1.1	V402C	Pathogenic	0.6
SLC26A4	O43511-1.1	V402D	Pathogenic	0.795
SLC26A4	O43511-1.1	V402E	Pathogenic	0.761
SLC26A4	O43511-1.1	V402F	Neutral	0.445
SLC26A4	O43511-1.1	V402G	Neutral	0.428
SLC26A4	O43511-1.1	V402H	Pathogenic	0.851
SLC26A4	O43511-1.1	V402I	Neutral	0.075
SLC26A4	O43511-1.1	V402K	Neutral	0.462
SLC26A4	O43511-1.1	V402L	Neutral	0.253
SLC26A4	O43511-1.1	V402M	Neutral	0.288
SLC26A4	O43511-1.1	V402N	Pathogenic	0.838
SLC26A4	O43511-1.1	V402P	Pathogenic	0.766
SLC26A4	O43511-1.1	V402Q	Pathogenic	0.749
SLC26A4	O43511-1.1	V402R	Neutral	0.488
SLC26A4	O43511-1.1	V402S	Pathogenic	0.531
SLC26A4	O43511-1.1	V402T	Neutral	0.437
SLC26A4	O43511-1.1	V402W	Neutral	0.434
SLC26A4	O43511-1.1	V402Y	Neutral	0.409
SLC26A4	O43511-1.1	A403C	Pathogenic	0.635
SLC26A4	O43511-1.1	A403D	Pathogenic	0.827
SLC26A4	O43511-1.1	A403E	Pathogenic	0.527
SLC26A4	O43511-1.1	A403F	Neutral	0.36
SLC26A4	O43511-1.1	A403G	Pathogenic	0.667
SLC26A4	O43511-1.1	A403H	Pathogenic	0.667
SLC26A4	O43511-1.1	A403I	Neutral	0.314
SLC26A4	O43511-1.1	A403K	Neutral	0.231
SLC26A4	O43511-1.1	A403L	Neutral	0.322
SLC26A4	O43511-1.1	A403M	Neutral	0.363
SLC26A4	O43511-1.1	A403N	Pathogenic	0.803
SLC26A4	O43511-1.1	A403P	Pathogenic	0.763
SLC26A4	O43511-1.1	A403Q	Pathogenic	0.51
SLC26A4	O43511-1.1	A403R	Neutral	0.142
SLC26A4	O43511-1.1	A403S	Pathogenic	0.638
SLC26A4	O43511-1.1	A403T	Pathogenic	0.617
SLC26A4	O43511-1.1	A403V	Neutral	0.402
SLC26A4	O43511-1.1	A403W	Neutral	0.211
SLC26A4	O43511-1.1	A403Y	Neutral	0.371
SLC26A4	O43511-1.1	T404A	Pathogenic	0.851
SLC26A4	O43511-1.1	T404C	Pathogenic	0.954
SLC26A4	O43511-1.1	T404D	Pathogenic	0.959
SLC26A4	O43511-1.1	T404E	Pathogenic	0.928
SLC26A4	O43511-1.1	T404F	Pathogenic	0.863
SLC26A4	O43511-1.1	T404G	Pathogenic	0.9
SLC26A4	O43511-1.1	T404H	Pathogenic	0.959
SLC26A4	O43511-1.1	T404I	Pathogenic	0.837
SLC26A4	O43511-1.1	T404K	Pathogenic	0.778
SLC26A4	O43511-1.1	T404L	Pathogenic	0.842
SLC26A4	O43511-1.1	T404M	Pathogenic	0.865
SLC26A4	O43511-1.1	T404N	Pathogenic	0.922
SLC26A4	O43511-1.1	T404P	Pathogenic	0.965
SLC26A4	O43511-1.1	T404Q	Pathogenic	0.924
SLC26A4	O43511-1.1	T404R	Pathogenic	0.66
SLC26A4	O43511-1.1	T404S	Pathogenic	0.772
SLC26A4	O43511-1.1	T404V	Pathogenic	0.883
SLC26A4	O43511-1.1	T404W	Pathogenic	0.599
SLC26A4	O43511-1.1	T404Y	Pathogenic	0.869
SLC26A4	O43511-1.1	T405A	Pathogenic	0.986
SLC26A4	O43511-1.1	T405C	Pathogenic	0.996
SLC26A4	O43511-1.1	T405D	Pathogenic	0.997
SLC26A4	O43511-1.1	T405E	Pathogenic	0.994
SLC26A4	O43511-1.1	T405F	Pathogenic	0.988
SLC26A4	O43511-1.1	T405G	Pathogenic	0.991
SLC26A4	O43511-1.1	T405H	Pathogenic	0.997
SLC26A4	O43511-1.1	T405I	Pathogenic	0.985
SLC26A4	O43511-1.1	T405K	Pathogenic	0.978
SLC26A4	O43511-1.1	T405L	Pathogenic	0.985
SLC26A4	O43511-1.1	T405M	Pathogenic	0.988
SLC26A4	O43511-1.1	T405N	Pathogenic	0.993
SLC26A4	O43511-1.1	T405P	Pathogenic	0.997
SLC26A4	O43511-1.1	T405Q	Pathogenic	0.994
SLC26A4	O43511-1.1	T405R	Pathogenic	0.961
SLC26A4	O43511-1.1	T405S	Pathogenic	0.977
SLC26A4	O43511-1.1	T405V	Pathogenic	0.99
SLC26A4	O43511-1.1	T405W	Pathogenic	0.949
SLC26A4	O43511-1.1	T405Y	Pathogenic	0.988
SLC26A4	O43511-1.1	A406C	Pathogenic	0.97
SLC26A4	O43511-1.1	A406D	Pathogenic	0.989
SLC26A4	O43511-1.1	A406E	Pathogenic	0.955
SLC26A4	O43511-1.1	A406F	Pathogenic	0.914
SLC26A4	O43511-1.1	A406G	Pathogenic	0.974
SLC26A4	O43511-1.1	A406H	Pathogenic	0.974
SLC26A4	O43511-1.1	A406I	Pathogenic	0.896
SLC26A4	O43511-1.1	A406K	Pathogenic	0.85
SLC26A4	O43511-1.1	A406L	Pathogenic	0.9
SLC26A4	O43511-1.1	A406M	Pathogenic	0.915
SLC26A4	O43511-1.1	A406N	Pathogenic	0.987
SLC26A4	O43511-1.1	A406P	Pathogenic	0.984
SLC26A4	O43511-1.1	A406Q	Pathogenic	0.952
SLC26A4	O43511-1.1	A406R	Pathogenic	0.758
SLC26A4	O43511-1.1	A406S	Pathogenic	0.971
SLC26A4	O43511-1.1	A406T	Pathogenic	0.968
SLC26A4	O43511-1.1	A406V	Pathogenic	0.927
SLC26A4	O43511-1.1	A406W	Pathogenic	0.835
SLC26A4	O43511-1.1	A406Y	Pathogenic	0.918
SLC26A4	O43511-1.1	L407A	Pathogenic	0.876
SLC26A4	O43511-1.1	L407C	Pathogenic	0.956
SLC26A4	O43511-1.1	L407D	Pathogenic	0.991
SLC26A4	O43511-1.1	L407E	Pathogenic	0.992
SLC26A4	O43511-1.1	L407F	Pathogenic	0.979
SLC26A4	O43511-1.1	L407G	Pathogenic	0.956
SLC26A4	O43511-1.1	L407H	Pathogenic	0.996
SLC26A4	O43511-1.1	L407I	Pathogenic	0.949
SLC26A4	O43511-1.1	L407K	Pathogenic	0.986
SLC26A4	O43511-1.1	L407M	Pathogenic	0.942
SLC26A4	O43511-1.1	L407N	Pathogenic	0.987
SLC26A4	O43511-1.1	L407P	Pathogenic	0.99
SLC26A4	O43511-1.1	L407Q	Pathogenic	0.99
SLC26A4	O43511-1.1	L407R	Pathogenic	0.974
SLC26A4	O43511-1.1	L407S	Pathogenic	0.942
SLC26A4	O43511-1.1	L407T	Pathogenic	0.957
SLC26A4	O43511-1.1	L407V	Pathogenic	0.933
SLC26A4	O43511-1.1	L407W	Pathogenic	0.978
SLC26A4	O43511-1.1	L407Y	Pathogenic	0.982
SLC26A4	O43511-1.1	S408A	Pathogenic	0.992
SLC26A4	O43511-1.1	S408C	Pathogenic	0.997
SLC26A4	O43511-1.1	S408D	Pathogenic	0.992
SLC26A4	O43511-1.1	S408E	Pathogenic	0.984
SLC26A4	O43511-1.1	S408F	Pathogenic	0.979
SLC26A4	O43511-1.1	S408G	Pathogenic	0.992
SLC26A4	O43511-1.1	S408H	Pathogenic	0.99
SLC26A4	O43511-1.1	S408I	Pathogenic	0.987
SLC26A4	O43511-1.1	S408K	Pathogenic	0.943
SLC26A4	O43511-1.1	S408L	Pathogenic	0.988
SLC26A4	O43511-1.1	S408M	Pathogenic	0.98
SLC26A4	O43511-1.1	S408N	Pathogenic	0.982
SLC26A4	O43511-1.1	S408P	Pathogenic	0.996
SLC26A4	O43511-1.1	S408Q	Pathogenic	0.983
SLC26A4	O43511-1.1	S408R	Pathogenic	0.948
SLC26A4	O43511-1.1	S408T	Pathogenic	0.986
SLC26A4	O43511-1.1	S408V	Pathogenic	0.996
SLC26A4	O43511-1.1	S408W	Pathogenic	0.958
SLC26A4	O43511-1.1	S408Y	Pathogenic	0.98
SLC26A4	O43511-1.1	R409A	Pathogenic	0.974
SLC26A4	O43511-1.1	R409C	Pathogenic	0.996
SLC26A4	O43511-1.1	R409D	Pathogenic	0.997
SLC26A4	O43511-1.1	R409E	Pathogenic	0.995
SLC26A4	O43511-1.1	R409F	Pathogenic	0.999
SLC26A4	O43511-1.1	R409G	Pathogenic	0.973
SLC26A4	O43511-1.1	R409H	Pathogenic	0.995
SLC26A4	O43511-1.1	R409I	Pathogenic	0.999
SLC26A4	O43511-1.1	R409K	Pathogenic	0.994
SLC26A4	O43511-1.1	R409L	Pathogenic	0.998
SLC26A4	O43511-1.1	R409M	Pathogenic	0.997
SLC26A4	O43511-1.1	R409N	Pathogenic	0.99
SLC26A4	O43511-1.1	R409P	Pathogenic	0.995
SLC26A4	O43511-1.1	R409Q	Pathogenic	0.99
SLC26A4	O43511-1.1	R409S	Pathogenic	0.983
SLC26A4	O43511-1.1	R409T	Pathogenic	0.992
SLC26A4	O43511-1.1	R409V	Pathogenic	0.998
SLC26A4	O43511-1.1	R409W	Pathogenic	0.999
SLC26A4	O43511-1.1	R409Y	Pathogenic	0.999
SLC26A4	O43511-1.1	T410A	Pathogenic	0.891
SLC26A4	O43511-1.1	T410C	Pathogenic	0.968
SLC26A4	O43511-1.1	T410D	Pathogenic	0.971
SLC26A4	O43511-1.1	T410E	Pathogenic	0.949
SLC26A4	O43511-1.1	T410F	Pathogenic	0.901
SLC26A4	O43511-1.1	T410G	Pathogenic	0.929
SLC26A4	O43511-1.1	T410H	Pathogenic	0.971
SLC26A4	O43511-1.1	T410I	Pathogenic	0.881
SLC26A4	O43511-1.1	T410K	Pathogenic	0.835
SLC26A4	O43511-1.1	T410L	Pathogenic	0.885
SLC26A4	O43511-1.1	T410M	Pathogenic	0.902
SLC26A4	O43511-1.1	T410N	Pathogenic	0.944
SLC26A4	O43511-1.1	T410P	Pathogenic	0.975
SLC26A4	O43511-1.1	T410Q	Pathogenic	0.946
SLC26A4	O43511-1.1	T410R	Pathogenic	0.737
SLC26A4	O43511-1.1	T410S	Pathogenic	0.83
SLC26A4	O43511-1.1	T410V	Pathogenic	0.916
SLC26A4	O43511-1.1	T410W	Pathogenic	0.683
SLC26A4	O43511-1.1	T410Y	Pathogenic	0.905
SLC26A4	O43511-1.1	A411C	Pathogenic	0.814
SLC26A4	O43511-1.1	A411D	Pathogenic	0.923
SLC26A4	O43511-1.1	A411E	Pathogenic	0.737
SLC26A4	O43511-1.1	A411F	Pathogenic	0.586
SLC26A4	O43511-1.1	A411G	Pathogenic	0.835
SLC26A4	O43511-1.1	A411H	Pathogenic	0.835
SLC26A4	O43511-1.1	A411I	Pathogenic	0.536
SLC26A4	O43511-1.1	A411K	Neutral	0.431
SLC26A4	O43511-1.1	A411L	Pathogenic	0.545
SLC26A4	O43511-1.1	A411M	Pathogenic	0.59
SLC26A4	O43511-1.1	A411N	Pathogenic	0.911
SLC26A4	O43511-1.1	A411P	Pathogenic	0.89
SLC26A4	O43511-1.1	A411Q	Pathogenic	0.725
SLC26A4	O43511-1.1	A411R	Neutral	0.295
SLC26A4	O43511-1.1	A411S	Pathogenic	0.817
SLC26A4	O43511-1.1	A411T	Pathogenic	0.802
SLC26A4	O43511-1.1	A411V	Pathogenic	0.629
SLC26A4	O43511-1.1	A411W	Neutral	0.403
SLC26A4	O43511-1.1	A411Y	Pathogenic	0.598
SLC26A4	O43511-1.1	V412A	Pathogenic	0.949
SLC26A4	O43511-1.1	V412C	Pathogenic	0.991
SLC26A4	O43511-1.1	V412D	Pathogenic	0.997
SLC26A4	O43511-1.1	V412E	Pathogenic	0.996
SLC26A4	O43511-1.1	V412F	Pathogenic	0.984
SLC26A4	O43511-1.1	V412G	Pathogenic	0.983
SLC26A4	O43511-1.1	V412H	Pathogenic	0.998
SLC26A4	O43511-1.1	V412I	Pathogenic	0.859
SLC26A4	O43511-1.1	V412K	Pathogenic	0.985
SLC26A4	O43511-1.1	V412L	Pathogenic	0.962
SLC26A4	O43511-1.1	V412M	Pathogenic	0.968
SLC26A4	O43511-1.1	V412N	Pathogenic	0.997
SLC26A4	O43511-1.1	V412P	Pathogenic	0.996
SLC26A4	O43511-1.1	V412Q	Pathogenic	0.996
SLC26A4	O43511-1.1	V412R	Pathogenic	0.986
SLC26A4	O43511-1.1	V412S	Pathogenic	0.988
SLC26A4	O43511-1.1	V412T	Pathogenic	0.983
SLC26A4	O43511-1.1	V412W	Pathogenic	0.983
SLC26A4	O43511-1.1	V412Y	Pathogenic	0.981
SLC26A4	O43511-1.1	Q413A	Pathogenic	0.997
SLC26A4	O43511-1.1	Q413C	Pathogenic	1.0
SLC26A4	O43511-1.1	Q413D	Pathogenic	0.998
SLC26A4	O43511-1.1	Q413E	Pathogenic	0.996
SLC26A4	O43511-1.1	Q413F	Pathogenic	1.0
SLC26A4	O43511-1.1	Q413G	Pathogenic	0.997
SLC26A4	O43511-1.1	Q413H	Pathogenic	0.999
SLC26A4	O43511-1.1	Q413I	Pathogenic	1.0
SLC26A4	O43511-1.1	Q413K	Pathogenic	0.996
SLC26A4	O43511-1.1	Q413L	Pathogenic	1.0
SLC26A4	O43511-1.1	Q413M	Pathogenic	0.998
SLC26A4	O43511-1.1	Q413N	Pathogenic	0.998
SLC26A4	O43511-1.1	Q413P	Pathogenic	0.999
SLC26A4	O43511-1.1	Q413R	Pathogenic	0.992
SLC26A4	O43511-1.1	Q413S	Pathogenic	0.996
SLC26A4	O43511-1.1	Q413T	Pathogenic	0.999
SLC26A4	O43511-1.1	Q413V	Pathogenic	1.0
SLC26A4	O43511-1.1	Q413W	Pathogenic	0.996
SLC26A4	O43511-1.1	Q413Y	Pathogenic	0.998
SLC26A4	O43511-1.1	E414A	Pathogenic	0.994
SLC26A4	O43511-1.1	E414C	Pathogenic	1.0
SLC26A4	O43511-1.1	E414D	Pathogenic	0.989
SLC26A4	O43511-1.1	E414F	Pathogenic	0.999
SLC26A4	O43511-1.1	E414G	Pathogenic	0.994
SLC26A4	O43511-1.1	E414H	Pathogenic	0.998
SLC26A4	O43511-1.1	E414I	Pathogenic	0.999
SLC26A4	O43511-1.1	E414K	Pathogenic	0.991
SLC26A4	O43511-1.1	E414L	Pathogenic	0.999
SLC26A4	O43511-1.1	E414M	Pathogenic	0.999
SLC26A4	O43511-1.1	E414N	Pathogenic	0.998
SLC26A4	O43511-1.1	E414P	Pathogenic	0.998
SLC26A4	O43511-1.1	E414Q	Pathogenic	0.993
SLC26A4	O43511-1.1	E414R	Pathogenic	0.992
SLC26A4	O43511-1.1	E414S	Pathogenic	0.993
SLC26A4	O43511-1.1	E414T	Pathogenic	0.998
SLC26A4	O43511-1.1	E414V	Pathogenic	0.999
SLC26A4	O43511-1.1	E414W	Pathogenic	0.995
SLC26A4	O43511-1.1	E414Y	Pathogenic	0.998
SLC26A4	O43511-1.1	S415A	Pathogenic	0.993
SLC26A4	O43511-1.1	S415C	Pathogenic	0.997
SLC26A4	O43511-1.1	S415D	Pathogenic	0.993
SLC26A4	O43511-1.1	S415E	Pathogenic	0.985
SLC26A4	O43511-1.1	S415F	Pathogenic	0.98
SLC26A4	O43511-1.1	S415G	Pathogenic	0.992
SLC26A4	O43511-1.1	S415H	Pathogenic	0.99
SLC26A4	O43511-1.1	S415I	Pathogenic	0.988
SLC26A4	O43511-1.1	S415K	Pathogenic	0.945
SLC26A4	O43511-1.1	S415L	Pathogenic	0.988
SLC26A4	O43511-1.1	S415M	Pathogenic	0.981
SLC26A4	O43511-1.1	S415N	Pathogenic	0.983
SLC26A4	O43511-1.1	S415P	Pathogenic	0.997
SLC26A4	O43511-1.1	S415Q	Pathogenic	0.984
SLC26A4	O43511-1.1	S415R	Pathogenic	0.95
SLC26A4	O43511-1.1	S415T	Pathogenic	0.987
SLC26A4	O43511-1.1	S415V	Pathogenic	0.996
SLC26A4	O43511-1.1	S415W	Pathogenic	0.959
SLC26A4	O43511-1.1	S415Y	Pathogenic	0.981
SLC26A4	O43511-1.1	T416A	Pathogenic	0.995
SLC26A4	O43511-1.1	T416C	Pathogenic	0.999
SLC26A4	O43511-1.1	T416D	Pathogenic	0.999
SLC26A4	O43511-1.1	T416E	Pathogenic	0.998
SLC26A4	O43511-1.1	T416F	Pathogenic	0.996
SLC26A4	O43511-1.1	T416G	Pathogenic	0.997
SLC26A4	O43511-1.1	T416H	Pathogenic	0.999
SLC26A4	O43511-1.1	T416I	Pathogenic	0.995
SLC26A4	O43511-1.1	T416K	Pathogenic	0.992
SLC26A4	O43511-1.1	T416L	Pathogenic	0.995
SLC26A4	O43511-1.1	T416M	Pathogenic	0.996
SLC26A4	O43511-1.1	T416N	Pathogenic	0.998
SLC26A4	O43511-1.1	T416P	Pathogenic	0.999
SLC26A4	O43511-1.1	T416Q	Pathogenic	0.998
SLC26A4	O43511-1.1	T416R	Pathogenic	0.986
SLC26A4	O43511-1.1	T416S	Pathogenic	0.992
SLC26A4	O43511-1.1	T416V	Pathogenic	0.996
SLC26A4	O43511-1.1	T416W	Pathogenic	0.982
SLC26A4	O43511-1.1	T416Y	Pathogenic	0.996
SLC26A4	O43511-1.1	G417A	Pathogenic	0.995
SLC26A4	O43511-1.1	G417C	Pathogenic	0.998
SLC26A4	O43511-1.1	G417D	Pathogenic	0.991
SLC26A4	O43511-1.1	G417E	Pathogenic	0.99
SLC26A4	O43511-1.1	G417F	Pathogenic	0.976
SLC26A4	O43511-1.1	G417H	Pathogenic	0.988
SLC26A4	O43511-1.1	G417I	Pathogenic	0.993
SLC26A4	O43511-1.1	G417K	Pathogenic	0.966
SLC26A4	O43511-1.1	G417L	Pathogenic	0.993
SLC26A4	O43511-1.1	G417M	Pathogenic	0.988
SLC26A4	O43511-1.1	G417N	Pathogenic	0.979
SLC26A4	O43511-1.1	G417P	Pathogenic	0.996
SLC26A4	O43511-1.1	G417Q	Pathogenic	0.99
SLC26A4	O43511-1.1	G417R	Pathogenic	0.94
SLC26A4	O43511-1.1	G417S	Pathogenic	0.994
SLC26A4	O43511-1.1	G417T	Pathogenic	0.996
SLC26A4	O43511-1.1	G417V	Pathogenic	0.995
SLC26A4	O43511-1.1	G417W	Pathogenic	0.83
SLC26A4	O43511-1.1	G417Y	Pathogenic	0.978
SLC26A4	O43511-1.1	G418A	Pathogenic	0.995
SLC26A4	O43511-1.1	G418C	Pathogenic	0.998
SLC26A4	O43511-1.1	G418D	Pathogenic	0.991
SLC26A4	O43511-1.1	G418E	Pathogenic	0.99
SLC26A4	O43511-1.1	G418F	Pathogenic	0.976
SLC26A4	O43511-1.1	G418H	Pathogenic	0.988
SLC26A4	O43511-1.1	G418I	Pathogenic	0.993
SLC26A4	O43511-1.1	G418K	Pathogenic	0.966
SLC26A4	O43511-1.1	G418L	Pathogenic	0.993
SLC26A4	O43511-1.1	G418M	Pathogenic	0.988
SLC26A4	O43511-1.1	G418N	Pathogenic	0.979
SLC26A4	O43511-1.1	G418P	Pathogenic	0.996
SLC26A4	O43511-1.1	G418Q	Pathogenic	0.99
SLC26A4	O43511-1.1	G418R	Pathogenic	0.94
SLC26A4	O43511-1.1	G418S	Pathogenic	0.994
SLC26A4	O43511-1.1	G418T	Pathogenic	0.996
SLC26A4	O43511-1.1	G418V	Pathogenic	0.995
SLC26A4	O43511-1.1	G418W	Pathogenic	0.83
SLC26A4	O43511-1.1	G418Y	Pathogenic	0.978
SLC26A4	O43511-1.1	K419A	Pathogenic	0.966
SLC26A4	O43511-1.1	K419C	Pathogenic	0.995
SLC26A4	O43511-1.1	K419D	Pathogenic	0.992
SLC26A4	O43511-1.1	K419E	Pathogenic	0.986
SLC26A4	O43511-1.1	K419F	Pathogenic	0.999
SLC26A4	O43511-1.1	K419G	Pathogenic	0.965
SLC26A4	O43511-1.1	K419H	Pathogenic	0.997
SLC26A4	O43511-1.1	K419I	Pathogenic	0.999
SLC26A4	O43511-1.1	K419L	Pathogenic	0.998
SLC26A4	O43511-1.1	K419M	Pathogenic	0.996
SLC26A4	O43511-1.1	K419N	Pathogenic	0.987
SLC26A4	O43511-1.1	K419P	Pathogenic	0.986
SLC26A4	O43511-1.1	K419Q	Pathogenic	0.986
SLC26A4	O43511-1.1	K419R	Pathogenic	0.986
SLC26A4	O43511-1.1	K419S	Pathogenic	0.955
SLC26A4	O43511-1.1	K419T	Pathogenic	0.99
SLC26A4	O43511-1.1	K419V	Pathogenic	0.996
SLC26A4	O43511-1.1	K419W	Pathogenic	0.997
SLC26A4	O43511-1.1	K419Y	Pathogenic	0.999
SLC26A4	O43511-1.1	T420A	Pathogenic	0.995
SLC26A4	O43511-1.1	T420C	Pathogenic	0.999
SLC26A4	O43511-1.1	T420D	Pathogenic	0.999
SLC26A4	O43511-1.1	T420E	Pathogenic	0.998
SLC26A4	O43511-1.1	T420F	Pathogenic	0.996
SLC26A4	O43511-1.1	T420G	Pathogenic	0.997
SLC26A4	O43511-1.1	T420H	Pathogenic	0.999
SLC26A4	O43511-1.1	T420I	Pathogenic	0.995
SLC26A4	O43511-1.1	T420K	Pathogenic	0.992
SLC26A4	O43511-1.1	T420L	Pathogenic	0.995
SLC26A4	O43511-1.1	T420M	Pathogenic	0.996
SLC26A4	O43511-1.1	T420N	Pathogenic	0.998
SLC26A4	O43511-1.1	T420P	Pathogenic	0.999
SLC26A4	O43511-1.1	T420Q	Pathogenic	0.998
SLC26A4	O43511-1.1	T420R	Pathogenic	0.986
SLC26A4	O43511-1.1	T420S	Pathogenic	0.992
SLC26A4	O43511-1.1	T420V	Pathogenic	0.996
SLC26A4	O43511-1.1	T420W	Pathogenic	0.982
SLC26A4	O43511-1.1	T420Y	Pathogenic	0.996
SLC26A4	O43511-1.1	Q421A	Pathogenic	0.997
SLC26A4	O43511-1.1	Q421C	Pathogenic	1.0
SLC26A4	O43511-1.1	Q421D	Pathogenic	0.998
SLC26A4	O43511-1.1	Q421E	Pathogenic	0.996
SLC26A4	O43511-1.1	Q421F	Pathogenic	1.0
SLC26A4	O43511-1.1	Q421G	Pathogenic	0.997
SLC26A4	O43511-1.1	Q421H	Pathogenic	0.999
SLC26A4	O43511-1.1	Q421I	Pathogenic	1.0
SLC26A4	O43511-1.1	Q421K	Pathogenic	0.996
SLC26A4	O43511-1.1	Q421L	Pathogenic	1.0
SLC26A4	O43511-1.1	Q421M	Pathogenic	0.998
SLC26A4	O43511-1.1	Q421N	Pathogenic	0.998
SLC26A4	O43511-1.1	Q421P	Pathogenic	0.999
SLC26A4	O43511-1.1	Q421R	Pathogenic	0.992
SLC26A4	O43511-1.1	Q421S	Pathogenic	0.996
SLC26A4	O43511-1.1	Q421T	Pathogenic	0.999
SLC26A4	O43511-1.1	Q421V	Pathogenic	1.0
SLC26A4	O43511-1.1	Q421W	Pathogenic	0.996
SLC26A4	O43511-1.1	Q421Y	Pathogenic	0.998
SLC26A4	O43511-1.1	V422A	Neutral	0.349
SLC26A4	O43511-1.1	V422C	Pathogenic	0.767
SLC26A4	O43511-1.1	V422D	Pathogenic	0.894
SLC26A4	O43511-1.1	V422E	Pathogenic	0.874
SLC26A4	O43511-1.1	V422F	Pathogenic	0.637
SLC26A4	O43511-1.1	V422G	Pathogenic	0.62
SLC26A4	O43511-1.1	V422H	Pathogenic	0.926
SLC26A4	O43511-1.1	V422I	Neutral	0.15
SLC26A4	O43511-1.1	V422K	Pathogenic	0.653
SLC26A4	O43511-1.1	V422L	Neutral	0.425
SLC26A4	O43511-1.1	V422M	Neutral	0.47
SLC26A4	O43511-1.1	V422N	Pathogenic	0.919
SLC26A4	O43511-1.1	V422P	Pathogenic	0.877
SLC26A4	O43511-1.1	V422Q	Pathogenic	0.867
SLC26A4	O43511-1.1	V422R	Pathogenic	0.676
SLC26A4	O43511-1.1	V422S	Pathogenic	0.713
SLC26A4	O43511-1.1	V422T	Pathogenic	0.629
SLC26A4	O43511-1.1	V422W	Pathogenic	0.626
SLC26A4	O43511-1.1	V422Y	Pathogenic	0.602
SLC26A4	O43511-1.1	A423C	Pathogenic	0.99
SLC26A4	O43511-1.1	A423D	Pathogenic	0.996
SLC26A4	O43511-1.1	A423E	Pathogenic	0.984
SLC26A4	O43511-1.1	A423F	Pathogenic	0.968
SLC26A4	O43511-1.1	A423G	Pathogenic	0.991
SLC26A4	O43511-1.1	A423H	Pathogenic	0.991
SLC26A4	O43511-1.1	A423I	Pathogenic	0.961
SLC26A4	O43511-1.1	A423K	Pathogenic	0.942
SLC26A4	O43511-1.1	A423L	Pathogenic	0.963
SLC26A4	O43511-1.1	A423M	Pathogenic	0.969
SLC26A4	O43511-1.1	A423N	Pathogenic	0.996
SLC26A4	O43511-1.1	A423P	Pathogenic	0.994
SLC26A4	O43511-1.1	A423Q	Pathogenic	0.983
SLC26A4	O43511-1.1	A423R	Pathogenic	0.9
SLC26A4	O43511-1.1	A423S	Pathogenic	0.99
SLC26A4	O43511-1.1	A423T	Pathogenic	0.989
SLC26A4	O43511-1.1	A423V	Pathogenic	0.973
SLC26A4	O43511-1.1	A423W	Pathogenic	0.936
SLC26A4	O43511-1.1	A423Y	Pathogenic	0.97
SLC26A4	O43511-1.1	G424A	Pathogenic	0.99
SLC26A4	O43511-1.1	G424C	Pathogenic	0.996
SLC26A4	O43511-1.1	G424D	Pathogenic	0.983
SLC26A4	O43511-1.1	G424E	Pathogenic	0.982
SLC26A4	O43511-1.1	G424F	Pathogenic	0.956
SLC26A4	O43511-1.1	G424H	Pathogenic	0.978
SLC26A4	O43511-1.1	G424I	Pathogenic	0.986
SLC26A4	O43511-1.1	G424K	Pathogenic	0.937
SLC26A4	O43511-1.1	G424L	Pathogenic	0.987
SLC26A4	O43511-1.1	G424M	Pathogenic	0.978
SLC26A4	O43511-1.1	G424N	Pathogenic	0.961
SLC26A4	O43511-1.1	G424P	Pathogenic	0.992
SLC26A4	O43511-1.1	G424Q	Pathogenic	0.981
SLC26A4	O43511-1.1	G424R	Pathogenic	0.891
SLC26A4	O43511-1.1	G424S	Pathogenic	0.989
SLC26A4	O43511-1.1	G424T	Pathogenic	0.992
SLC26A4	O43511-1.1	G424V	Pathogenic	0.991
SLC26A4	O43511-1.1	G424W	Pathogenic	0.721
SLC26A4	O43511-1.1	G424Y	Pathogenic	0.958
SLC26A4	O43511-1.1	I425A	Neutral	0.27
SLC26A4	O43511-1.1	I425C	Pathogenic	0.531
SLC26A4	O43511-1.1	I425D	Pathogenic	0.744
SLC26A4	O43511-1.1	I425E	Pathogenic	0.873
SLC26A4	O43511-1.1	I425F	Pathogenic	0.722
SLC26A4	O43511-1.1	I425G	Pathogenic	0.531
SLC26A4	O43511-1.1	I425H	Pathogenic	0.933
SLC26A4	O43511-1.1	I425K	Pathogenic	0.878
SLC26A4	O43511-1.1	I425L	Pathogenic	0.506
SLC26A4	O43511-1.1	I425M	Pathogenic	0.632
SLC26A4	O43511-1.1	I425N	Pathogenic	0.796
SLC26A4	O43511-1.1	I425P	Pathogenic	0.832
SLC26A4	O43511-1.1	I425Q	Pathogenic	0.91
SLC26A4	O43511-1.1	I425R	Pathogenic	0.8
SLC26A4	O43511-1.1	I425S	Neutral	0.46
SLC26A4	O43511-1.1	I425T	Pathogenic	0.54
SLC26A4	O43511-1.1	I425V	Neutral	0.152
SLC26A4	O43511-1.1	I425W	Pathogenic	0.834
SLC26A4	O43511-1.1	I425Y	Pathogenic	0.743
SLC26A4	O43511-1.1	I426A	Pathogenic	0.513
SLC26A4	O43511-1.1	I426C	Pathogenic	0.763
SLC26A4	O43511-1.1	I426D	Pathogenic	0.892
SLC26A4	O43511-1.1	I426E	Pathogenic	0.952
SLC26A4	O43511-1.1	I426F	Pathogenic	0.881
SLC26A4	O43511-1.1	I426G	Pathogenic	0.763
SLC26A4	O43511-1.1	I426H	Pathogenic	0.975
SLC26A4	O43511-1.1	I426K	Pathogenic	0.954
SLC26A4	O43511-1.1	I426L	Pathogenic	0.744
SLC26A4	O43511-1.1	I426M	Pathogenic	0.83
SLC26A4	O43511-1.1	I426N	Pathogenic	0.917
SLC26A4	O43511-1.1	I426P	Pathogenic	0.934
SLC26A4	O43511-1.1	I426Q	Pathogenic	0.967
SLC26A4	O43511-1.1	I426R	Pathogenic	0.919
SLC26A4	O43511-1.1	I426S	Pathogenic	0.708
SLC26A4	O43511-1.1	I426T	Pathogenic	0.769
SLC26A4	O43511-1.1	I426V	Neutral	0.338
SLC26A4	O43511-1.1	I426W	Pathogenic	0.935
SLC26A4	O43511-1.1	I426Y	Pathogenic	0.892
SLC26A4	O43511-1.1	S427A	Pathogenic	0.985
SLC26A4	O43511-1.1	S427C	Pathogenic	0.993
SLC26A4	O43511-1.1	S427D	Pathogenic	0.985
SLC26A4	O43511-1.1	S427E	Pathogenic	0.968
SLC26A4	O43511-1.1	S427F	Pathogenic	0.959
SLC26A4	O43511-1.1	S427G	Pathogenic	0.984
SLC26A4	O43511-1.1	S427H	Pathogenic	0.979
SLC26A4	O43511-1.1	S427I	Pathogenic	0.975
SLC26A4	O43511-1.1	S427K	Pathogenic	0.89
SLC26A4	O43511-1.1	S427L	Pathogenic	0.975
SLC26A4	O43511-1.1	S427M	Pathogenic	0.96
SLC26A4	O43511-1.1	S427N	Pathogenic	0.965
SLC26A4	O43511-1.1	S427P	Pathogenic	0.993
SLC26A4	O43511-1.1	S427Q	Pathogenic	0.966
SLC26A4	O43511-1.1	S427R	Pathogenic	0.9
SLC26A4	O43511-1.1	S427T	Pathogenic	0.972
SLC26A4	O43511-1.1	S427V	Pathogenic	0.991
SLC26A4	O43511-1.1	S427W	Pathogenic	0.917
SLC26A4	O43511-1.1	S427Y	Pathogenic	0.961
SLC26A4	O43511-1.1	A428C	Pathogenic	0.966
SLC26A4	O43511-1.1	A428D	Pathogenic	0.987
SLC26A4	O43511-1.1	A428E	Pathogenic	0.948
SLC26A4	O43511-1.1	A428F	Pathogenic	0.902
SLC26A4	O43511-1.1	A428G	Pathogenic	0.97
SLC26A4	O43511-1.1	A428H	Pathogenic	0.97
SLC26A4	O43511-1.1	A428I	Pathogenic	0.882
SLC26A4	O43511-1.1	A428K	Pathogenic	0.83
SLC26A4	O43511-1.1	A428L	Pathogenic	0.886
SLC26A4	O43511-1.1	A428M	Pathogenic	0.903
SLC26A4	O43511-1.1	A428N	Pathogenic	0.985
SLC26A4	O43511-1.1	A428P	Pathogenic	0.981
SLC26A4	O43511-1.1	A428Q	Pathogenic	0.944
SLC26A4	O43511-1.1	A428R	Pathogenic	0.73
SLC26A4	O43511-1.1	A428S	Pathogenic	0.966
SLC26A4	O43511-1.1	A428T	Pathogenic	0.963
SLC26A4	O43511-1.1	A428V	Pathogenic	0.916
SLC26A4	O43511-1.1	A428W	Pathogenic	0.813
SLC26A4	O43511-1.1	A428Y	Pathogenic	0.906
SLC26A4	O43511-1.1	A429C	Neutral	0.006
SLC26A4	O43511-1.1	A429D	Neutral	0.017
SLC26A4	O43511-1.1	A429E	Neutral	0.004
SLC26A4	O43511-1.1	A429F	Neutral	0.002
SLC26A4	O43511-1.1	A429G	Neutral	0.007
SLC26A4	O43511-1.1	A429H	Neutral	0.007
SLC26A4	O43511-1.1	A429I	Neutral	0.002
SLC26A4	O43511-1.1	A429K	Neutral	0.001
SLC26A4	O43511-1.1	A429L	Neutral	0.002
SLC26A4	O43511-1.1	A429M	Neutral	0.002
SLC26A4	O43511-1.1	A429N	Neutral	0.014
SLC26A4	O43511-1.1	A429P	Neutral	0.011
SLC26A4	O43511-1.1	A429Q	Neutral	0.004
SLC26A4	O43511-1.1	A429R	Neutral	0.001
SLC26A4	O43511-1.1	A429S	Neutral	0.006
SLC26A4	O43511-1.1	A429T	Neutral	0.006
SLC26A4	O43511-1.1	A429V	Neutral	0.002
SLC26A4	O43511-1.1	A429W	Neutral	0.001
SLC26A4	O43511-1.1	A429Y	Neutral	0.002
SLC26A4	O43511-1.1	I430A	Pathogenic	0.683
SLC26A4	O43511-1.1	I430C	Pathogenic	0.868
SLC26A4	O43511-1.1	I430D	Pathogenic	0.944
SLC26A4	O43511-1.1	I430E	Pathogenic	0.976
SLC26A4	O43511-1.1	I430F	Pathogenic	0.938
SLC26A4	O43511-1.1	I430G	Pathogenic	0.868
SLC26A4	O43511-1.1	I430H	Pathogenic	0.988
SLC26A4	O43511-1.1	I430K	Pathogenic	0.977
SLC26A4	O43511-1.1	I430L	Pathogenic	0.856
SLC26A4	O43511-1.1	I430M	Pathogenic	0.909
SLC26A4	O43511-1.1	I430N	Pathogenic	0.958
SLC26A4	O43511-1.1	I430P	Pathogenic	0.966
SLC26A4	O43511-1.1	I430Q	Pathogenic	0.983
SLC26A4	O43511-1.1	I430R	Pathogenic	0.959
SLC26A4	O43511-1.1	I430S	Pathogenic	0.832
SLC26A4	O43511-1.1	I430T	Pathogenic	0.872
SLC26A4	O43511-1.1	I430V	Pathogenic	0.51
SLC26A4	O43511-1.1	I430W	Pathogenic	0.967
SLC26A4	O43511-1.1	I430Y	Pathogenic	0.944
SLC26A4	O43511-1.1	V431A	Pathogenic	0.95
SLC26A4	O43511-1.1	V431C	Pathogenic	0.991
SLC26A4	O43511-1.1	V431D	Pathogenic	0.997
SLC26A4	O43511-1.1	V431E	Pathogenic	0.996
SLC26A4	O43511-1.1	V431F	Pathogenic	0.984
SLC26A4	O43511-1.1	V431G	Pathogenic	0.983
SLC26A4	O43511-1.1	V431H	Pathogenic	0.998
SLC26A4	O43511-1.1	V431I	Pathogenic	0.861
SLC26A4	O43511-1.1	V431K	Pathogenic	0.985
SLC26A4	O43511-1.1	V431L	Pathogenic	0.963
SLC26A4	O43511-1.1	V431M	Pathogenic	0.969
SLC26A4	O43511-1.1	V431N	Pathogenic	0.997
SLC26A4	O43511-1.1	V431P	Pathogenic	0.996
SLC26A4	O43511-1.1	V431Q	Pathogenic	0.996
SLC26A4	O43511-1.1	V431R	Pathogenic	0.987
SLC26A4	O43511-1.1	V431S	Pathogenic	0.989
SLC26A4	O43511-1.1	V431T	Pathogenic	0.984
SLC26A4	O43511-1.1	V431W	Pathogenic	0.983
SLC26A4	O43511-1.1	V431Y	Pathogenic	0.982
SLC26A4	O43511-1.1	M432A	Pathogenic	0.909
SLC26A4	O43511-1.1	M432C	Pathogenic	0.968
SLC26A4	O43511-1.1	M432D	Pathogenic	0.987
SLC26A4	O43511-1.1	M432E	Pathogenic	0.989
SLC26A4	O43511-1.1	M432F	Pathogenic	0.978
SLC26A4	O43511-1.1	M432G	Pathogenic	0.938
SLC26A4	O43511-1.1	M432H	Pathogenic	0.995
SLC26A4	O43511-1.1	M432I	Pathogenic	0.974
SLC26A4	O43511-1.1	M432K	Pathogenic	0.98
SLC26A4	O43511-1.1	M432L	Pathogenic	0.95
SLC26A4	O43511-1.1	M432N	Pathogenic	0.981
SLC26A4	O43511-1.1	M432P	Pathogenic	0.985
SLC26A4	O43511-1.1	M432Q	Pathogenic	0.971
SLC26A4	O43511-1.1	M432R	Pathogenic	0.964
SLC26A4	O43511-1.1	M432S	Pathogenic	0.919
SLC26A4	O43511-1.1	M432T	Pathogenic	0.969
SLC26A4	O43511-1.1	M432V	Pathogenic	0.951
SLC26A4	O43511-1.1	M432W	Pathogenic	0.956
SLC26A4	O43511-1.1	M432Y	Pathogenic	0.987
SLC26A4	O43511-1.1	I433A	Pathogenic	0.723
SLC26A4	O43511-1.1	I433C	Pathogenic	0.889
SLC26A4	O43511-1.1	I433D	Pathogenic	0.954
SLC26A4	O43511-1.1	I433E	Pathogenic	0.98
SLC26A4	O43511-1.1	I433F	Pathogenic	0.948
SLC26A4	O43511-1.1	I433G	Pathogenic	0.889
SLC26A4	O43511-1.1	I433H	Pathogenic	0.99
SLC26A4	O43511-1.1	I433K	Pathogenic	0.981
SLC26A4	O43511-1.1	I433L	Pathogenic	0.878
SLC26A4	O43511-1.1	I433M	Pathogenic	0.924
SLC26A4	O43511-1.1	I433N	Pathogenic	0.965
SLC26A4	O43511-1.1	I433P	Pathogenic	0.972
SLC26A4	O43511-1.1	I433Q	Pathogenic	0.986
SLC26A4	O43511-1.1	I433R	Pathogenic	0.966
SLC26A4	O43511-1.1	I433S	Pathogenic	0.858
SLC26A4	O43511-1.1	I433T	Pathogenic	0.892
SLC26A4	O43511-1.1	I433V	Pathogenic	0.559
SLC26A4	O43511-1.1	I433W	Pathogenic	0.973
SLC26A4	O43511-1.1	I433Y	Pathogenic	0.953
SLC26A4	O43511-1.1	A434C	Neutral	0.499
SLC26A4	O43511-1.1	A434D	Pathogenic	0.733
SLC26A4	O43511-1.1	A434E	Neutral	0.39
SLC26A4	O43511-1.1	A434F	Neutral	0.244
SLC26A4	O43511-1.1	A434G	Pathogenic	0.535
SLC26A4	O43511-1.1	A434H	Pathogenic	0.535
SLC26A4	O43511-1.1	A434I	Neutral	0.208
SLC26A4	O43511-1.1	A434K	Neutral	0.147
SLC26A4	O43511-1.1	A434L	Neutral	0.215
SLC26A4	O43511-1.1	A434M	Neutral	0.247
SLC26A4	O43511-1.1	A434N	Pathogenic	0.701
SLC26A4	O43511-1.1	A434P	Pathogenic	0.649
SLC26A4	O43511-1.1	A434Q	Neutral	0.375
SLC26A4	O43511-1.1	A434R	Neutral	0.087
SLC26A4	O43511-1.1	A434S	Pathogenic	0.503
SLC26A4	O43511-1.1	A434T	Neutral	0.48
SLC26A4	O43511-1.1	A434V	Neutral	0.279
SLC26A4	O43511-1.1	A434W	Neutral	0.133
SLC26A4	O43511-1.1	A434Y	Neutral	0.253
SLC26A4	O43511-1.1	I435A	Pathogenic	0.803
SLC26A4	O43511-1.1	I435C	Pathogenic	0.926
SLC26A4	O43511-1.1	I435D	Pathogenic	0.97
SLC26A4	O43511-1.1	I435E	Pathogenic	0.987
SLC26A4	O43511-1.1	I435F	Pathogenic	0.966
SLC26A4	O43511-1.1	I435G	Pathogenic	0.926
SLC26A4	O43511-1.1	I435H	Pathogenic	0.994
SLC26A4	O43511-1.1	I435K	Pathogenic	0.988
SLC26A4	O43511-1.1	I435L	Pathogenic	0.919
SLC26A4	O43511-1.1	I435M	Pathogenic	0.95
SLC26A4	O43511-1.1	I435N	Pathogenic	0.977
SLC26A4	O43511-1.1	I435P	Pathogenic	0.982
SLC26A4	O43511-1.1	I435Q	Pathogenic	0.991
SLC26A4	O43511-1.1	I435R	Pathogenic	0.978
SLC26A4	O43511-1.1	I435S	Pathogenic	0.904
SLC26A4	O43511-1.1	I435T	Pathogenic	0.928
SLC26A4	O43511-1.1	I435V	Pathogenic	0.664
SLC26A4	O43511-1.1	I435W	Pathogenic	0.982
SLC26A4	O43511-1.1	I435Y	Pathogenic	0.97
SLC26A4	O43511-1.1	L436A	Neutral	0.238
SLC26A4	O43511-1.1	L436C	Neutral	0.489
SLC26A4	O43511-1.1	L436D	Pathogenic	0.832
SLC26A4	O43511-1.1	L436E	Pathogenic	0.854
SLC26A4	O43511-1.1	L436F	Pathogenic	0.672
SLC26A4	O43511-1.1	L436G	Neutral	0.489
SLC26A4	O43511-1.1	L436H	Pathogenic	0.922
SLC26A4	O43511-1.1	L436I	Neutral	0.454
SLC26A4	O43511-1.1	L436K	Pathogenic	0.752
SLC26A4	O43511-1.1	L436M	Neutral	0.419
SLC26A4	O43511-1.1	L436N	Pathogenic	0.767
SLC26A4	O43511-1.1	L436P	Pathogenic	0.807
SLC26A4	O43511-1.1	L436Q	Pathogenic	0.81
SLC26A4	O43511-1.1	L436R	Pathogenic	0.627
SLC26A4	O43511-1.1	L436S	Neutral	0.419
SLC26A4	O43511-1.1	L436T	Neutral	0.498
SLC26A4	O43511-1.1	L436V	Neutral	0.379
SLC26A4	O43511-1.1	L436W	Pathogenic	0.662
SLC26A4	O43511-1.1	L436Y	Pathogenic	0.71
SLC26A4	O43511-1.1	A437C	Pathogenic	0.98
SLC26A4	O43511-1.1	A437D	Pathogenic	0.993
SLC26A4	O43511-1.1	A437E	Pathogenic	0.969
SLC26A4	O43511-1.1	A437F	Pathogenic	0.94
SLC26A4	O43511-1.1	A437G	Pathogenic	0.982
SLC26A4	O43511-1.1	A437H	Pathogenic	0.982
SLC26A4	O43511-1.1	A437I	Pathogenic	0.928
SLC26A4	O43511-1.1	A437K	Pathogenic	0.894
SLC26A4	O43511-1.1	A437L	Pathogenic	0.93
SLC26A4	O43511-1.1	A437M	Pathogenic	0.941
SLC26A4	O43511-1.1	A437N	Pathogenic	0.991
SLC26A4	O43511-1.1	A437P	Pathogenic	0.989
SLC26A4	O43511-1.1	A437Q	Pathogenic	0.967
SLC26A4	O43511-1.1	A437R	Pathogenic	0.823
SLC26A4	O43511-1.1	A437S	Pathogenic	0.98
SLC26A4	O43511-1.1	A437T	Pathogenic	0.978
SLC26A4	O43511-1.1	A437V	Pathogenic	0.95
SLC26A4	O43511-1.1	A437W	Pathogenic	0.882
SLC26A4	O43511-1.1	A437Y	Pathogenic	0.943
SLC26A4	O43511-1.1	L438A	Neutral	0.251
SLC26A4	O43511-1.1	L438C	Pathogenic	0.506
SLC26A4	O43511-1.1	L438D	Pathogenic	0.841
SLC26A4	O43511-1.1	L438E	Pathogenic	0.862
SLC26A4	O43511-1.1	L438F	Pathogenic	0.687
SLC26A4	O43511-1.1	L438G	Pathogenic	0.505
SLC26A4	O43511-1.1	L438H	Pathogenic	0.926
SLC26A4	O43511-1.1	L438I	Neutral	0.47
SLC26A4	O43511-1.1	L438K	Pathogenic	0.765
SLC26A4	O43511-1.1	L438M	Neutral	0.436
SLC26A4	O43511-1.1	L438N	Pathogenic	0.779
SLC26A4	O43511-1.1	L438P	Pathogenic	0.817
SLC26A4	O43511-1.1	L438Q	Pathogenic	0.821
SLC26A4	O43511-1.1	L438R	Pathogenic	0.642
SLC26A4	O43511-1.1	L438S	Neutral	0.435
SLC26A4	O43511-1.1	L438T	Pathogenic	0.515
SLC26A4	O43511-1.1	L438V	Neutral	0.395
SLC26A4	O43511-1.1	L438W	Pathogenic	0.677
SLC26A4	O43511-1.1	L438Y	Pathogenic	0.723
SLC26A4	O43511-1.1	G439A	Pathogenic	0.991
SLC26A4	O43511-1.1	G439C	Pathogenic	0.997
SLC26A4	O43511-1.1	G439D	Pathogenic	0.985
SLC26A4	O43511-1.1	G439E	Pathogenic	0.984
SLC26A4	O43511-1.1	G439F	Pathogenic	0.961
SLC26A4	O43511-1.1	G439H	Pathogenic	0.98
SLC26A4	O43511-1.1	G439I	Pathogenic	0.988
SLC26A4	O43511-1.1	G439K	Pathogenic	0.943
SLC26A4	O43511-1.1	G439L	Pathogenic	0.988
SLC26A4	O43511-1.1	G439M	Pathogenic	0.98
SLC26A4	O43511-1.1	G439N	Pathogenic	0.965
SLC26A4	O43511-1.1	G439P	Pathogenic	0.993
SLC26A4	O43511-1.1	G439Q	Pathogenic	0.983
SLC26A4	O43511-1.1	G439R	Pathogenic	0.902
SLC26A4	O43511-1.1	G439S	Pathogenic	0.99
SLC26A4	O43511-1.1	G439T	Pathogenic	0.993
SLC26A4	O43511-1.1	G439V	Pathogenic	0.992
SLC26A4	O43511-1.1	G439W	Pathogenic	0.743
SLC26A4	O43511-1.1	G439Y	Pathogenic	0.963
SLC26A4	O43511-1.1	K440A	Neutral	0.202
SLC26A4	O43511-1.1	K440C	Pathogenic	0.65
SLC26A4	O43511-1.1	K440D	Pathogenic	0.531
SLC26A4	O43511-1.1	K440E	Neutral	0.375
SLC26A4	O43511-1.1	K440F	Pathogenic	0.925
SLC26A4	O43511-1.1	K440G	Neutral	0.195
SLC26A4	O43511-1.1	K440H	Pathogenic	0.73
SLC26A4	O43511-1.1	K440I	Pathogenic	0.882
SLC26A4	O43511-1.1	K440L	Pathogenic	0.795
SLC26A4	O43511-1.1	K440M	Pathogenic	0.699
SLC26A4	O43511-1.1	K440N	Neutral	0.398
SLC26A4	O43511-1.1	K440P	Neutral	0.379
SLC26A4	O43511-1.1	K440Q	Neutral	0.39
SLC26A4	O43511-1.1	K440R	Neutral	0.38
SLC26A4	O43511-1.1	K440S	Neutral	0.158
SLC26A4	O43511-1.1	K440T	Neutral	0.455
SLC26A4	O43511-1.1	K440V	Pathogenic	0.665
SLC26A4	O43511-1.1	K440W	Pathogenic	0.746
SLC26A4	O43511-1.1	K440Y	Pathogenic	0.866
SLC26A4	O43511-1.1	L441A	Pathogenic	0.924
SLC26A4	O43511-1.1	L441C	Pathogenic	0.974
SLC26A4	O43511-1.1	L441D	Pathogenic	0.995
SLC26A4	O43511-1.1	L441E	Pathogenic	0.996
SLC26A4	O43511-1.1	L441F	Pathogenic	0.988
SLC26A4	O43511-1.1	L441G	Pathogenic	0.974
SLC26A4	O43511-1.1	L441H	Pathogenic	0.998
SLC26A4	O43511-1.1	L441I	Pathogenic	0.97
SLC26A4	O43511-1.1	L441K	Pathogenic	0.992
SLC26A4	O43511-1.1	L441M	Pathogenic	0.966
SLC26A4	O43511-1.1	L441N	Pathogenic	0.992
SLC26A4	O43511-1.1	L441P	Pathogenic	0.994
SLC26A4	O43511-1.1	L441Q	Pathogenic	0.994
SLC26A4	O43511-1.1	L441R	Pathogenic	0.985
SLC26A4	O43511-1.1	L441S	Pathogenic	0.966
SLC26A4	O43511-1.1	L441T	Pathogenic	0.975
SLC26A4	O43511-1.1	L441V	Pathogenic	0.96
SLC26A4	O43511-1.1	L441W	Pathogenic	0.987
SLC26A4	O43511-1.1	L441Y	Pathogenic	0.99
SLC26A4	O43511-1.1	L442A	Pathogenic	0.808
SLC26A4	O43511-1.1	L442C	Pathogenic	0.928
SLC26A4	O43511-1.1	L442D	Pathogenic	0.985
SLC26A4	O43511-1.1	L442E	Pathogenic	0.987
SLC26A4	O43511-1.1	L442F	Pathogenic	0.965
SLC26A4	O43511-1.1	L442G	Pathogenic	0.928
SLC26A4	O43511-1.1	L442H	Pathogenic	0.994
SLC26A4	O43511-1.1	L442I	Pathogenic	0.918
SLC26A4	O43511-1.1	L442K	Pathogenic	0.976
SLC26A4	O43511-1.1	L442M	Pathogenic	0.907
SLC26A4	O43511-1.1	L442N	Pathogenic	0.978
SLC26A4	O43511-1.1	L442P	Pathogenic	0.983
SLC26A4	O43511-1.1	L442Q	Pathogenic	0.983
SLC26A4	O43511-1.1	L442R	Pathogenic	0.958
SLC26A4	O43511-1.1	L442S	Pathogenic	0.907
SLC26A4	O43511-1.1	L442T	Pathogenic	0.93
SLC26A4	O43511-1.1	L442V	Pathogenic	0.892
SLC26A4	O43511-1.1	L442W	Pathogenic	0.964
SLC26A4	O43511-1.1	L442Y	Pathogenic	0.971
SLC26A4	O43511-1.1	E443A	Pathogenic	0.945
SLC26A4	O43511-1.1	E443C	Pathogenic	0.996
SLC26A4	O43511-1.1	E443D	Pathogenic	0.895
SLC26A4	O43511-1.1	E443F	Pathogenic	0.988
SLC26A4	O43511-1.1	E443G	Pathogenic	0.943
SLC26A4	O43511-1.1	E443H	Pathogenic	0.976
SLC26A4	O43511-1.1	E443I	Pathogenic	0.992
SLC26A4	O43511-1.1	E443K	Pathogenic	0.917
SLC26A4	O43511-1.1	E443L	Pathogenic	0.993
SLC26A4	O43511-1.1	E443M	Pathogenic	0.988
SLC26A4	O43511-1.1	E443N	Pathogenic	0.978
SLC26A4	O43511-1.1	E443P	Pathogenic	0.976
SLC26A4	O43511-1.1	E443Q	Pathogenic	0.932
SLC26A4	O43511-1.1	E443R	Pathogenic	0.924
SLC26A4	O43511-1.1	E443S	Pathogenic	0.927
SLC26A4	O43511-1.1	E443T	Pathogenic	0.983
SLC26A4	O43511-1.1	E443V	Pathogenic	0.993
SLC26A4	O43511-1.1	E443W	Pathogenic	0.95
SLC26A4	O43511-1.1	E443Y	Pathogenic	0.977
SLC26A4	O43511-1.1	P444A	Pathogenic	0.998
SLC26A4	O43511-1.1	P444C	Pathogenic	1.0
SLC26A4	O43511-1.1	P444D	Pathogenic	0.999
SLC26A4	O43511-1.1	P444E	Pathogenic	0.998
SLC26A4	O43511-1.1	P444F	Pathogenic	0.999
SLC26A4	O43511-1.1	P444G	Pathogenic	0.998
SLC26A4	O43511-1.1	P444H	Pathogenic	0.999
SLC26A4	O43511-1.1	P444I	Pathogenic	0.999
SLC26A4	O43511-1.1	P444K	Pathogenic	0.992
SLC26A4	O43511-1.1	P444L	Pathogenic	0.999
SLC26A4	O43511-1.1	P444M	Pathogenic	0.998
SLC26A4	O43511-1.1	P444N	Pathogenic	0.999
SLC26A4	O43511-1.1	P444Q	Pathogenic	0.998
SLC26A4	O43511-1.1	P444R	Pathogenic	0.993
SLC26A4	O43511-1.1	P444S	Pathogenic	0.998
SLC26A4	O43511-1.1	P444T	Pathogenic	0.999
SLC26A4	O43511-1.1	P444V	Pathogenic	0.999
SLC26A4	O43511-1.1	P444W	Pathogenic	0.997
SLC26A4	O43511-1.1	P444Y	Pathogenic	0.998
SLC26A4	O43511-1.1	L445A	Pathogenic	0.942
SLC26A4	O43511-1.1	L445C	Pathogenic	0.98
SLC26A4	O43511-1.1	L445D	Pathogenic	0.996
SLC26A4	O43511-1.1	L445E	Pathogenic	0.997
SLC26A4	O43511-1.1	L445F	Pathogenic	0.991
SLC26A4	O43511-1.1	L445G	Pathogenic	0.98
SLC26A4	O43511-1.1	L445H	Pathogenic	0.998
SLC26A4	O43511-1.1	L445I	Pathogenic	0.978
SLC26A4	O43511-1.1	L445K	Pathogenic	0.994
SLC26A4	O43511-1.1	L445M	Pathogenic	0.974
SLC26A4	O43511-1.1	L445N	Pathogenic	0.994
SLC26A4	O43511-1.1	L445P	Pathogenic	0.995
SLC26A4	O43511-1.1	L445Q	Pathogenic	0.996
SLC26A4	O43511-1.1	L445R	Pathogenic	0.989
SLC26A4	O43511-1.1	L445S	Pathogenic	0.974
SLC26A4	O43511-1.1	L445T	Pathogenic	0.981
SLC26A4	O43511-1.1	L445V	Pathogenic	0.97
SLC26A4	O43511-1.1	L445W	Pathogenic	0.99
SLC26A4	O43511-1.1	L445Y	Pathogenic	0.992
SLC26A4	O43511-1.1	Q446A	Pathogenic	0.987
SLC26A4	O43511-1.1	Q446C	Pathogenic	0.998
SLC26A4	O43511-1.1	Q446D	Pathogenic	0.991
SLC26A4	O43511-1.1	Q446E	Pathogenic	0.985
SLC26A4	O43511-1.1	Q446F	Pathogenic	0.998
SLC26A4	O43511-1.1	Q446G	Pathogenic	0.987
SLC26A4	O43511-1.1	Q446H	Pathogenic	0.996
SLC26A4	O43511-1.1	Q446I	Pathogenic	0.999
SLC26A4	O43511-1.1	Q446K	Pathogenic	0.982
SLC26A4	O43511-1.1	Q446L	Pathogenic	0.998
SLC26A4	O43511-1.1	Q446M	Pathogenic	0.993
SLC26A4	O43511-1.1	Q446N	Pathogenic	0.993
SLC26A4	O43511-1.1	Q446P	Pathogenic	0.995
SLC26A4	O43511-1.1	Q446R	Pathogenic	0.969
SLC26A4	O43511-1.1	Q446S	Pathogenic	0.983
SLC26A4	O43511-1.1	Q446T	Pathogenic	0.996
SLC26A4	O43511-1.1	Q446V	Pathogenic	0.998
SLC26A4	O43511-1.1	Q446W	Pathogenic	0.985
SLC26A4	O43511-1.1	Q446Y	Pathogenic	0.993
SLC26A4	O43511-1.1	K447A	Pathogenic	0.905
SLC26A4	O43511-1.1	K447C	Pathogenic	0.986
SLC26A4	O43511-1.1	K447D	Pathogenic	0.977
SLC26A4	O43511-1.1	K447E	Pathogenic	0.958
SLC26A4	O43511-1.1	K447F	Pathogenic	0.998
SLC26A4	O43511-1.1	K447G	Pathogenic	0.901
SLC26A4	O43511-1.1	K447H	Pathogenic	0.99
SLC26A4	O43511-1.1	K447I	Pathogenic	0.996
SLC26A4	O43511-1.1	K447L	Pathogenic	0.993
SLC26A4	O43511-1.1	K447M	Pathogenic	0.989
SLC26A4	O43511-1.1	K447N	Pathogenic	0.961
SLC26A4	O43511-1.1	K447P	Pathogenic	0.958
SLC26A4	O43511-1.1	K447Q	Pathogenic	0.96
SLC26A4	O43511-1.1	K447R	Pathogenic	0.958
SLC26A4	O43511-1.1	K447S	Pathogenic	0.877
SLC26A4	O43511-1.1	K447T	Pathogenic	0.969
SLC26A4	O43511-1.1	K447V	Pathogenic	0.987
SLC26A4	O43511-1.1	K447W	Pathogenic	0.991
SLC26A4	O43511-1.1	K447Y	Pathogenic	0.996
SLC26A4	O43511-1.1	S448A	Pathogenic	0.981
SLC26A4	O43511-1.1	S448C	Pathogenic	0.992
SLC26A4	O43511-1.1	S448D	Pathogenic	0.981
SLC26A4	O43511-1.1	S448E	Pathogenic	0.96
SLC26A4	O43511-1.1	S448F	Pathogenic	0.95
SLC26A4	O43511-1.1	S448G	Pathogenic	0.98
SLC26A4	O43511-1.1	S448H	Pathogenic	0.975
SLC26A4	O43511-1.1	S448I	Pathogenic	0.969
SLC26A4	O43511-1.1	S448K	Pathogenic	0.867
SLC26A4	O43511-1.1	S448L	Pathogenic	0.97
SLC26A4	O43511-1.1	S448M	Pathogenic	0.95
SLC26A4	O43511-1.1	S448N	Pathogenic	0.957
SLC26A4	O43511-1.1	S448P	Pathogenic	0.991
SLC26A4	O43511-1.1	S448Q	Pathogenic	0.958
SLC26A4	O43511-1.1	S448R	Pathogenic	0.879
SLC26A4	O43511-1.1	S448T	Pathogenic	0.965
SLC26A4	O43511-1.1	S448V	Pathogenic	0.989
SLC26A4	O43511-1.1	S448W	Pathogenic	0.9
SLC26A4	O43511-1.1	S448Y	Pathogenic	0.952
SLC26A4	O43511-1.1	V449A	Pathogenic	0.957
SLC26A4	O43511-1.1	V449C	Pathogenic	0.993
SLC26A4	O43511-1.1	V449D	Pathogenic	0.997
SLC26A4	O43511-1.1	V449E	Pathogenic	0.997
SLC26A4	O43511-1.1	V449F	Pathogenic	0.987
SLC26A4	O43511-1.1	V449G	Pathogenic	0.986
SLC26A4	O43511-1.1	V449H	Pathogenic	0.998
SLC26A4	O43511-1.1	V449I	Pathogenic	0.88
SLC26A4	O43511-1.1	V449K	Pathogenic	0.987
SLC26A4	O43511-1.1	V449L	Pathogenic	0.969
SLC26A4	O43511-1.1	V449M	Pathogenic	0.974
SLC26A4	O43511-1.1	V449N	Pathogenic	0.998
SLC26A4	O43511-1.1	V449P	Pathogenic	0.997
SLC26A4	O43511-1.1	V449Q	Pathogenic	0.996
SLC26A4	O43511-1.1	V449R	Pathogenic	0.989
SLC26A4	O43511-1.1	V449S	Pathogenic	0.99
SLC26A4	O43511-1.1	V449T	Pathogenic	0.986
SLC26A4	O43511-1.1	V449W	Pathogenic	0.986
SLC26A4	O43511-1.1	V449Y	Pathogenic	0.984
SLC26A4	O43511-1.1	L450A	Pathogenic	0.927
SLC26A4	O43511-1.1	L450C	Pathogenic	0.975
SLC26A4	O43511-1.1	L450D	Pathogenic	0.995
SLC26A4	O43511-1.1	L450E	Pathogenic	0.996
SLC26A4	O43511-1.1	L450F	Pathogenic	0.988
SLC26A4	O43511-1.1	L450G	Pathogenic	0.975
SLC26A4	O43511-1.1	L450H	Pathogenic	0.998
SLC26A4	O43511-1.1	L450I	Pathogenic	0.971
SLC26A4	O43511-1.1	L450K	Pathogenic	0.992
SLC26A4	O43511-1.1	L450M	Pathogenic	0.967
SLC26A4	O43511-1.1	L450N	Pathogenic	0.993
SLC26A4	O43511-1.1	L450P	Pathogenic	0.994
SLC26A4	O43511-1.1	L450Q	Pathogenic	0.994
SLC26A4	O43511-1.1	L450R	Pathogenic	0.986
SLC26A4	O43511-1.1	L450S	Pathogenic	0.967
SLC26A4	O43511-1.1	L450T	Pathogenic	0.976
SLC26A4	O43511-1.1	L450V	Pathogenic	0.961
SLC26A4	O43511-1.1	L450W	Pathogenic	0.988
SLC26A4	O43511-1.1	L450Y	Pathogenic	0.99
SLC26A4	O43511-1.1	A451C	Pathogenic	0.967
SLC26A4	O43511-1.1	A451D	Pathogenic	0.988
SLC26A4	O43511-1.1	A451E	Pathogenic	0.949
SLC26A4	O43511-1.1	A451F	Pathogenic	0.904
SLC26A4	O43511-1.1	A451G	Pathogenic	0.971
SLC26A4	O43511-1.1	A451H	Pathogenic	0.971
SLC26A4	O43511-1.1	A451I	Pathogenic	0.884
SLC26A4	O43511-1.1	A451K	Pathogenic	0.834
SLC26A4	O43511-1.1	A451L	Pathogenic	0.888
SLC26A4	O43511-1.1	A451M	Pathogenic	0.905
SLC26A4	O43511-1.1	A451N	Pathogenic	0.986
SLC26A4	O43511-1.1	A451P	Pathogenic	0.982
SLC26A4	O43511-1.1	A451Q	Pathogenic	0.946
SLC26A4	O43511-1.1	A451R	Pathogenic	0.735
SLC26A4	O43511-1.1	A451S	Pathogenic	0.967
SLC26A4	O43511-1.1	A451T	Pathogenic	0.964
SLC26A4	O43511-1.1	A451V	Pathogenic	0.918
SLC26A4	O43511-1.1	A451W	Pathogenic	0.817
SLC26A4	O43511-1.1	A451Y	Pathogenic	0.908
SLC26A4	O43511-1.1	A452C	Pathogenic	0.944
SLC26A4	O43511-1.1	A452D	Pathogenic	0.979
SLC26A4	O43511-1.1	A452E	Pathogenic	0.915
SLC26A4	O43511-1.1	A452F	Pathogenic	0.845
SLC26A4	O43511-1.1	A452G	Pathogenic	0.951
SLC26A4	O43511-1.1	A452H	Pathogenic	0.951
SLC26A4	O43511-1.1	A452I	Pathogenic	0.816
SLC26A4	O43511-1.1	A452K	Pathogenic	0.744
SLC26A4	O43511-1.1	A452L	Pathogenic	0.822
SLC26A4	O43511-1.1	A452M	Pathogenic	0.847
SLC26A4	O43511-1.1	A452N	Pathogenic	0.975
SLC26A4	O43511-1.1	A452P	Pathogenic	0.969
SLC26A4	O43511-1.1	A452Q	Pathogenic	0.91
SLC26A4	O43511-1.1	A452R	Pathogenic	0.617
SLC26A4	O43511-1.1	A452S	Pathogenic	0.945
SLC26A4	O43511-1.1	A452T	Pathogenic	0.94
SLC26A4	O43511-1.1	A452V	Pathogenic	0.867
SLC26A4	O43511-1.1	A452W	Pathogenic	0.722
SLC26A4	O43511-1.1	A452Y	Pathogenic	0.851
SLC26A4	O43511-1.1	V453A	Neutral	0.265
SLC26A4	O43511-1.1	V453C	Pathogenic	0.689
SLC26A4	O43511-1.1	V453D	Pathogenic	0.851
SLC26A4	O43511-1.1	V453E	Pathogenic	0.824
SLC26A4	O43511-1.1	V453F	Pathogenic	0.542
SLC26A4	O43511-1.1	V453G	Pathogenic	0.524
SLC26A4	O43511-1.1	V453H	Pathogenic	0.894
SLC26A4	O43511-1.1	V453I	Neutral	0.106
SLC26A4	O43511-1.1	V453K	Pathogenic	0.558
SLC26A4	O43511-1.1	V453L	Neutral	0.332
SLC26A4	O43511-1.1	V453M	Neutral	0.374
SLC26A4	O43511-1.1	V453N	Pathogenic	0.884
SLC26A4	O43511-1.1	V453P	Pathogenic	0.828
SLC26A4	O43511-1.1	V453Q	Pathogenic	0.814
SLC26A4	O43511-1.1	V453R	Pathogenic	0.584
SLC26A4	O43511-1.1	V453S	Pathogenic	0.625
SLC26A4	O43511-1.1	V453T	Pathogenic	0.533
SLC26A4	O43511-1.1	V453W	Pathogenic	0.53
SLC26A4	O43511-1.1	V453Y	Pathogenic	0.504
SLC26A4	O43511-1.1	V454A	Pathogenic	0.518
SLC26A4	O43511-1.1	V454C	Pathogenic	0.868
SLC26A4	O43511-1.1	V454D	Pathogenic	0.944
SLC26A4	O43511-1.1	V454E	Pathogenic	0.933
SLC26A4	O43511-1.1	V454F	Pathogenic	0.779
SLC26A4	O43511-1.1	V454G	Pathogenic	0.766
SLC26A4	O43511-1.1	V454H	Pathogenic	0.962
SLC26A4	O43511-1.1	V454I	Neutral	0.261
SLC26A4	O43511-1.1	V454K	Pathogenic	0.79
SLC26A4	O43511-1.1	V454L	Pathogenic	0.597
SLC26A4	O43511-1.1	V454M	Pathogenic	0.64
SLC26A4	O43511-1.1	V454N	Pathogenic	0.958
SLC26A4	O43511-1.1	V454P	Pathogenic	0.935
SLC26A4	O43511-1.1	V454Q	Pathogenic	0.929
SLC26A4	O43511-1.1	V454R	Pathogenic	0.807
SLC26A4	O43511-1.1	V454S	Pathogenic	0.833
SLC26A4	O43511-1.1	V454T	Pathogenic	0.773
SLC26A4	O43511-1.1	V454W	Pathogenic	0.771
SLC26A4	O43511-1.1	V454Y	Pathogenic	0.752
SLC26A4	O43511-1.1	I455A	Neutral	0.242
SLC26A4	O43511-1.1	I455C	Neutral	0.495
SLC26A4	O43511-1.1	I455D	Pathogenic	0.716
SLC26A4	O43511-1.1	I455E	Pathogenic	0.857
SLC26A4	O43511-1.1	I455F	Pathogenic	0.692
SLC26A4	O43511-1.1	I455G	Neutral	0.494
SLC26A4	O43511-1.1	I455H	Pathogenic	0.923
SLC26A4	O43511-1.1	I455K	Pathogenic	0.862
SLC26A4	O43511-1.1	I455L	Neutral	0.469
SLC26A4	O43511-1.1	I455M	Pathogenic	0.597
SLC26A4	O43511-1.1	I455N	Pathogenic	0.771
SLC26A4	O43511-1.1	I455P	Pathogenic	0.81
SLC26A4	O43511-1.1	I455Q	Pathogenic	0.898
SLC26A4	O43511-1.1	I455R	Pathogenic	0.776
SLC26A4	O43511-1.1	I455S	Neutral	0.425
SLC26A4	O43511-1.1	I455T	Pathogenic	0.504
SLC26A4	O43511-1.1	I455V	Neutral	0.134
SLC26A4	O43511-1.1	I455W	Pathogenic	0.813
SLC26A4	O43511-1.1	I455Y	Pathogenic	0.715
SLC26A4	O43511-1.1	A456C	Neutral	0.48
SLC26A4	O43511-1.1	A456D	Pathogenic	0.717
SLC26A4	O43511-1.1	A456E	Neutral	0.371
SLC26A4	O43511-1.1	A456F	Neutral	0.23
SLC26A4	O43511-1.1	A456G	Pathogenic	0.515
SLC26A4	O43511-1.1	A456H	Pathogenic	0.515
SLC26A4	O43511-1.1	A456I	Neutral	0.195
SLC26A4	O43511-1.1	A456K	Neutral	0.137
SLC26A4	O43511-1.1	A456L	Neutral	0.202
SLC26A4	O43511-1.1	A456M	Neutral	0.232
SLC26A4	O43511-1.1	A456N	Pathogenic	0.684
SLC26A4	O43511-1.1	A456P	Pathogenic	0.631
SLC26A4	O43511-1.1	A456Q	Neutral	0.356
SLC26A4	O43511-1.1	A456R	Neutral	0.081
SLC26A4	O43511-1.1	A456S	Neutral	0.484
SLC26A4	O43511-1.1	A456T	Neutral	0.461
SLC26A4	O43511-1.1	A456V	Neutral	0.263
SLC26A4	O43511-1.1	A456W	Neutral	0.124
SLC26A4	O43511-1.1	A456Y	Neutral	0.239
SLC26A4	O43511-1.1	N457A	Pathogenic	0.999
SLC26A4	O43511-1.1	N457C	Pathogenic	1.0
SLC26A4	O43511-1.1	N457D	Pathogenic	0.997
SLC26A4	O43511-1.1	N457E	Pathogenic	0.998
SLC26A4	O43511-1.1	N457F	Pathogenic	0.998
SLC26A4	O43511-1.1	N457G	Pathogenic	0.99
SLC26A4	O43511-1.1	N457H	Pathogenic	0.993
SLC26A4	O43511-1.1	N457I	Pathogenic	0.999
SLC26A4	O43511-1.1	N457K	Pathogenic	0.994
SLC26A4	O43511-1.1	N457L	Pathogenic	0.999
SLC26A4	O43511-1.1	N457M	Pathogenic	0.998
SLC26A4	O43511-1.1	N457P	Pathogenic	0.999
SLC26A4	O43511-1.1	N457Q	Pathogenic	0.998
SLC26A4	O43511-1.1	N457R	Pathogenic	0.989
SLC26A4	O43511-1.1	N457S	Pathogenic	0.993
SLC26A4	O43511-1.1	N457T	Pathogenic	0.999
SLC26A4	O43511-1.1	N457V	Pathogenic	1.0
SLC26A4	O43511-1.1	N457W	Pathogenic	0.996
SLC26A4	O43511-1.1	N457Y	Pathogenic	0.997
SLC26A4	O43511-1.1	L458A	Pathogenic	0.927
SLC26A4	O43511-1.1	L458C	Pathogenic	0.975
SLC26A4	O43511-1.1	L458D	Pathogenic	0.995
SLC26A4	O43511-1.1	L458E	Pathogenic	0.996
SLC26A4	O43511-1.1	L458F	Pathogenic	0.988
SLC26A4	O43511-1.1	L458G	Pathogenic	0.975
SLC26A4	O43511-1.1	L458H	Pathogenic	0.998
SLC26A4	O43511-1.1	L458I	Pathogenic	0.971
SLC26A4	O43511-1.1	L458K	Pathogenic	0.992
SLC26A4	O43511-1.1	L458M	Pathogenic	0.967
SLC26A4	O43511-1.1	L458N	Pathogenic	0.993
SLC26A4	O43511-1.1	L458P	Pathogenic	0.994
SLC26A4	O43511-1.1	L458Q	Pathogenic	0.994
SLC26A4	O43511-1.1	L458R	Pathogenic	0.986
SLC26A4	O43511-1.1	L458S	Pathogenic	0.967
SLC26A4	O43511-1.1	L458T	Pathogenic	0.976
SLC26A4	O43511-1.1	L458V	Pathogenic	0.961
SLC26A4	O43511-1.1	L458W	Pathogenic	0.988
SLC26A4	O43511-1.1	L458Y	Pathogenic	0.99
SLC26A4	O43511-1.1	K459A	Pathogenic	0.962
SLC26A4	O43511-1.1	K459C	Pathogenic	0.995
SLC26A4	O43511-1.1	K459D	Pathogenic	0.991
SLC26A4	O43511-1.1	K459E	Pathogenic	0.984
SLC26A4	O43511-1.1	K459F	Pathogenic	0.999
SLC26A4	O43511-1.1	K459G	Pathogenic	0.961
SLC26A4	O43511-1.1	K459H	Pathogenic	0.996
SLC26A4	O43511-1.1	K459I	Pathogenic	0.999
SLC26A4	O43511-1.1	K459L	Pathogenic	0.997
SLC26A4	O43511-1.1	K459M	Pathogenic	0.996
SLC26A4	O43511-1.1	K459N	Pathogenic	0.985
SLC26A4	O43511-1.1	K459P	Pathogenic	0.984
SLC26A4	O43511-1.1	K459Q	Pathogenic	0.985
SLC26A4	O43511-1.1	K459R	Pathogenic	0.984
SLC26A4	O43511-1.1	K459S	Pathogenic	0.95
SLC26A4	O43511-1.1	K459T	Pathogenic	0.988
SLC26A4	O43511-1.1	K459V	Pathogenic	0.995
SLC26A4	O43511-1.1	K459W	Pathogenic	0.997
SLC26A4	O43511-1.1	K459Y	Pathogenic	0.998
SLC26A4	O43511-1.1	G460A	Pathogenic	0.993
SLC26A4	O43511-1.1	G460C	Pathogenic	0.997
SLC26A4	O43511-1.1	G460D	Pathogenic	0.988
SLC26A4	O43511-1.1	G460E	Pathogenic	0.987
SLC26A4	O43511-1.1	G460F	Pathogenic	0.968
SLC26A4	O43511-1.1	G460H	Pathogenic	0.984
SLC26A4	O43511-1.1	G460I	Pathogenic	0.99
SLC26A4	O43511-1.1	G460K	Pathogenic	0.953
SLC26A4	O43511-1.1	G460L	Pathogenic	0.99
SLC26A4	O43511-1.1	G460M	Pathogenic	0.984
SLC26A4	O43511-1.1	G460N	Pathogenic	0.971
SLC26A4	O43511-1.1	G460P	Pathogenic	0.994
SLC26A4	O43511-1.1	G460Q	Pathogenic	0.986
SLC26A4	O43511-1.1	G460R	Pathogenic	0.918
SLC26A4	O43511-1.1	G460S	Pathogenic	0.992
SLC26A4	O43511-1.1	G460T	Pathogenic	0.994
SLC26A4	O43511-1.1	G460V	Pathogenic	0.993
SLC26A4	O43511-1.1	G460W	Pathogenic	0.778
SLC26A4	O43511-1.1	G460Y	Pathogenic	0.969
SLC26A4	O43511-1.1	M461A	Pathogenic	0.997
SLC26A4	O43511-1.1	M461C	Pathogenic	0.999
SLC26A4	O43511-1.1	M461D	Pathogenic	1.0
SLC26A4	O43511-1.1	M461E	Pathogenic	1.0
SLC26A4	O43511-1.1	M461F	Pathogenic	0.999
SLC26A4	O43511-1.1	M461G	Pathogenic	0.998
SLC26A4	O43511-1.1	M461H	Pathogenic	1.0
SLC26A4	O43511-1.1	M461I	Pathogenic	0.999
SLC26A4	O43511-1.1	M461K	Pathogenic	0.999
SLC26A4	O43511-1.1	M461L	Pathogenic	0.999
SLC26A4	O43511-1.1	M461N	Pathogenic	0.999
SLC26A4	O43511-1.1	M461P	Pathogenic	1.0
SLC26A4	O43511-1.1	M461Q	Pathogenic	0.999
SLC26A4	O43511-1.1	M461R	Pathogenic	0.999
SLC26A4	O43511-1.1	M461S	Pathogenic	0.998
SLC26A4	O43511-1.1	M461T	Pathogenic	0.999
SLC26A4	O43511-1.1	M461V	Pathogenic	0.999
SLC26A4	O43511-1.1	M461W	Pathogenic	0.999
SLC26A4	O43511-1.1	M461Y	Pathogenic	1.0
SLC26A4	O43511-1.1	F462A	Pathogenic	0.622
SLC26A4	O43511-1.1	F462C	Pathogenic	0.834
SLC26A4	O43511-1.1	F462D	Pathogenic	0.866
SLC26A4	O43511-1.1	F462E	Pathogenic	0.939
SLC26A4	O43511-1.1	F462G	Pathogenic	0.555
SLC26A4	O43511-1.1	F462H	Pathogenic	0.884
SLC26A4	O43511-1.1	F462I	Pathogenic	0.904
SLC26A4	O43511-1.1	F462K	Pathogenic	0.977
SLC26A4	O43511-1.1	F462L	Pathogenic	0.901
SLC26A4	O43511-1.1	F462M	Pathogenic	0.884
SLC26A4	O43511-1.1	F462N	Pathogenic	0.896
SLC26A4	O43511-1.1	F462P	Pathogenic	0.956
SLC26A4	O43511-1.1	F462Q	Pathogenic	0.957
SLC26A4	O43511-1.1	F462R	Pathogenic	0.96
SLC26A4	O43511-1.1	F462S	Pathogenic	0.654
SLC26A4	O43511-1.1	F462T	Pathogenic	0.839
SLC26A4	O43511-1.1	F462V	Pathogenic	0.866
SLC26A4	O43511-1.1	F462W	Pathogenic	0.646
SLC26A4	O43511-1.1	F462Y	Pathogenic	0.515
SLC26A4	O43511-1.1	M463A	Pathogenic	0.988
SLC26A4	O43511-1.1	M463C	Pathogenic	0.996
SLC26A4	O43511-1.1	M463D	Pathogenic	0.998
SLC26A4	O43511-1.1	M463E	Pathogenic	0.999
SLC26A4	O43511-1.1	M463F	Pathogenic	0.997
SLC26A4	O43511-1.1	M463G	Pathogenic	0.992
SLC26A4	O43511-1.1	M463H	Pathogenic	0.999
SLC26A4	O43511-1.1	M463I	Pathogenic	0.997
SLC26A4	O43511-1.1	M463K	Pathogenic	0.997
SLC26A4	O43511-1.1	M463L	Pathogenic	0.994
SLC26A4	O43511-1.1	M463N	Pathogenic	0.998
SLC26A4	O43511-1.1	M463P	Pathogenic	0.998
SLC26A4	O43511-1.1	M463Q	Pathogenic	0.996
SLC26A4	O43511-1.1	M463R	Pathogenic	0.995
SLC26A4	O43511-1.1	M463S	Pathogenic	0.989
SLC26A4	O43511-1.1	M463T	Pathogenic	0.996
SLC26A4	O43511-1.1	M463V	Pathogenic	0.994
SLC26A4	O43511-1.1	M463W	Pathogenic	0.994
SLC26A4	O43511-1.1	M463Y	Pathogenic	0.998
SLC26A4	O43511-1.1	Q464A	Pathogenic	0.996
SLC26A4	O43511-1.1	Q464C	Pathogenic	0.999
SLC26A4	O43511-1.1	Q464D	Pathogenic	0.997
SLC26A4	O43511-1.1	Q464E	Pathogenic	0.995
SLC26A4	O43511-1.1	Q464F	Pathogenic	0.999
SLC26A4	O43511-1.1	Q464G	Pathogenic	0.996
SLC26A4	O43511-1.1	Q464H	Pathogenic	0.999
SLC26A4	O43511-1.1	Q464I	Pathogenic	1.0
SLC26A4	O43511-1.1	Q464K	Pathogenic	0.994
SLC26A4	O43511-1.1	Q464L	Pathogenic	0.999
SLC26A4	O43511-1.1	Q464M	Pathogenic	0.998
SLC26A4	O43511-1.1	Q464N	Pathogenic	0.998
SLC26A4	O43511-1.1	Q464P	Pathogenic	0.998
SLC26A4	O43511-1.1	Q464R	Pathogenic	0.989
SLC26A4	O43511-1.1	Q464S	Pathogenic	0.994
SLC26A4	O43511-1.1	Q464T	Pathogenic	0.999
SLC26A4	O43511-1.1	Q464V	Pathogenic	0.999
SLC26A4	O43511-1.1	Q464W	Pathogenic	0.995
SLC26A4	O43511-1.1	Q464Y	Pathogenic	0.998
SLC26A4	O43511-1.1	L465A	Neutral	0.0
SLC26A4	O43511-1.1	L465C	Neutral	0.001
SLC26A4	O43511-1.1	L465D	Neutral	0.004
SLC26A4	O43511-1.1	L465E	Neutral	0.005
SLC26A4	O43511-1.1	L465F	Neutral	0.002
SLC26A4	O43511-1.1	L465G	Neutral	0.001
SLC26A4	O43511-1.1	L465H	Neutral	0.01
SLC26A4	O43511-1.1	L465I	Neutral	0.001
SLC26A4	O43511-1.1	L465K	Neutral	0.003
SLC26A4	O43511-1.1	L465M	Neutral	0.001
SLC26A4	O43511-1.1	L465N	Neutral	0.003
SLC26A4	O43511-1.1	L465P	Neutral	0.003
SLC26A4	O43511-1.1	L465Q	Neutral	0.004
SLC26A4	O43511-1.1	L465R	Neutral	0.001
SLC26A4	O43511-1.1	L465S	Neutral	0.001
SLC26A4	O43511-1.1	L465T	Neutral	0.001
SLC26A4	O43511-1.1	L465V	Neutral	0.001
SLC26A4	O43511-1.1	L465W	Neutral	0.002
SLC26A4	O43511-1.1	L465Y	Neutral	0.002
SLC26A4	O43511-1.1	C466A	Pathogenic	0.519
SLC26A4	O43511-1.1	C466D	Pathogenic	0.916
SLC26A4	O43511-1.1	C466E	Pathogenic	0.911
SLC26A4	O43511-1.1	C466F	Pathogenic	0.517
SLC26A4	O43511-1.1	C466G	Pathogenic	0.767
SLC26A4	O43511-1.1	C466H	Pathogenic	0.82
SLC26A4	O43511-1.1	C466I	Neutral	0.465
SLC26A4	O43511-1.1	C466K	Pathogenic	0.578
SLC26A4	O43511-1.1	C466L	Neutral	0.475
SLC26A4	O43511-1.1	C466M	Pathogenic	0.52
SLC26A4	O43511-1.1	C466N	Pathogenic	0.903
SLC26A4	O43511-1.1	C466P	Pathogenic	0.953
SLC26A4	O43511-1.1	C466Q	Pathogenic	0.826
SLC26A4	O43511-1.1	C466R	Neutral	0.431
SLC26A4	O43511-1.1	C466S	Pathogenic	0.714
SLC26A4	O43511-1.1	C466T	Pathogenic	0.785
SLC26A4	O43511-1.1	C466V	Pathogenic	0.72
SLC26A4	O43511-1.1	C466W	Neutral	0.202
SLC26A4	O43511-1.1	C466Y	Pathogenic	0.525
SLC26A4	O43511-1.1	D467A	Pathogenic	0.962
SLC26A4	O43511-1.1	D467C	Pathogenic	0.989
SLC26A4	O43511-1.1	D467E	Pathogenic	0.744
SLC26A4	O43511-1.1	D467F	Pathogenic	0.92
SLC26A4	O43511-1.1	D467G	Pathogenic	0.856
SLC26A4	O43511-1.1	D467H	Pathogenic	0.921
SLC26A4	O43511-1.1	D467I	Pathogenic	0.95
SLC26A4	O43511-1.1	D467K	Pathogenic	0.876
SLC26A4	O43511-1.1	D467L	Pathogenic	0.975
SLC26A4	O43511-1.1	D467M	Pathogenic	0.959
SLC26A4	O43511-1.1	D467N	Pathogenic	0.912
SLC26A4	O43511-1.1	D467P	Pathogenic	0.968
SLC26A4	O43511-1.1	D467Q	Pathogenic	0.888
SLC26A4	O43511-1.1	D467R	Pathogenic	0.887
SLC26A4	O43511-1.1	D467S	Pathogenic	0.903
SLC26A4	O43511-1.1	D467T	Pathogenic	0.972
SLC26A4	O43511-1.1	D467V	Pathogenic	0.982
SLC26A4	O43511-1.1	D467W	Pathogenic	0.846
SLC26A4	O43511-1.1	D467Y	Pathogenic	0.924
SLC26A4	O43511-1.1	I468A	Neutral	0.337
SLC26A4	O43511-1.1	I468C	Pathogenic	0.609
SLC26A4	O43511-1.1	I468D	Pathogenic	0.8
SLC26A4	O43511-1.1	I468E	Pathogenic	0.905
SLC26A4	O43511-1.1	I468F	Pathogenic	0.781
SLC26A4	O43511-1.1	I468G	Pathogenic	0.608
SLC26A4	O43511-1.1	I468H	Pathogenic	0.95
SLC26A4	O43511-1.1	I468K	Pathogenic	0.909
SLC26A4	O43511-1.1	I468L	Pathogenic	0.584
SLC26A4	O43511-1.1	I468M	Pathogenic	0.702
SLC26A4	O43511-1.1	I468N	Pathogenic	0.843
SLC26A4	O43511-1.1	I468P	Pathogenic	0.872
SLC26A4	O43511-1.1	I468Q	Pathogenic	0.933
SLC26A4	O43511-1.1	I468R	Pathogenic	0.846
SLC26A4	O43511-1.1	I468S	Pathogenic	0.54
SLC26A4	O43511-1.1	I468T	Pathogenic	0.617
SLC26A4	O43511-1.1	I468V	Neutral	0.198
SLC26A4	O43511-1.1	I468W	Pathogenic	0.874
SLC26A4	O43511-1.1	I468Y	Pathogenic	0.799
SLC26A4	O43511-1.1	P469A	Pathogenic	0.737
SLC26A4	O43511-1.1	P469C	Pathogenic	0.966
SLC26A4	O43511-1.1	P469D	Pathogenic	0.833
SLC26A4	O43511-1.1	P469E	Pathogenic	0.699
SLC26A4	O43511-1.1	P469F	Pathogenic	0.867
SLC26A4	O43511-1.1	P469G	Pathogenic	0.679
SLC26A4	O43511-1.1	P469H	Pathogenic	0.807
SLC26A4	O43511-1.1	P469I	Pathogenic	0.841
SLC26A4	O43511-1.1	P469K	Neutral	0.386
SLC26A4	O43511-1.1	P469L	Pathogenic	0.846
SLC26A4	O43511-1.1	P469M	Pathogenic	0.767
SLC26A4	O43511-1.1	P469N	Pathogenic	0.895
SLC26A4	O43511-1.1	P469Q	Pathogenic	0.686
SLC26A4	O43511-1.1	P469R	Neutral	0.411
SLC26A4	O43511-1.1	P469S	Pathogenic	0.762
SLC26A4	O43511-1.1	P469T	Pathogenic	0.871
SLC26A4	O43511-1.1	P469V	Pathogenic	0.886
SLC26A4	O43511-1.1	P469W	Pathogenic	0.606
SLC26A4	O43511-1.1	P469Y	Pathogenic	0.773
SLC26A4	O43511-1.1	R470A	Neutral	0.269
SLC26A4	O43511-1.1	R470C	Pathogenic	0.73
SLC26A4	O43511-1.1	R470D	Pathogenic	0.768
SLC26A4	O43511-1.1	R470E	Pathogenic	0.637
SLC26A4	O43511-1.1	R470F	Pathogenic	0.948
SLC26A4	O43511-1.1	R470G	Neutral	0.261
SLC26A4	O43511-1.1	R470H	Pathogenic	0.662
SLC26A4	O43511-1.1	R470I	Pathogenic	0.916
SLC26A4	O43511-1.1	R470K	Pathogenic	0.617
SLC26A4	O43511-1.1	R470L	Pathogenic	0.85
SLC26A4	O43511-1.1	R470M	Pathogenic	0.772
SLC26A4	O43511-1.1	R470N	Neutral	0.491
SLC26A4	O43511-1.1	R470P	Pathogenic	0.641
SLC26A4	O43511-1.1	R470Q	Neutral	0.483
SLC26A4	O43511-1.1	R470S	Neutral	0.355
SLC26A4	O43511-1.1	R470T	Pathogenic	0.548
SLC26A4	O43511-1.1	R470V	Pathogenic	0.853
SLC26A4	O43511-1.1	R470W	Pathogenic	0.933
SLC26A4	O43511-1.1	R470Y	Pathogenic	0.942
SLC26A4	O43511-1.1	L471A	Pathogenic	0.883
SLC26A4	O43511-1.1	L471C	Pathogenic	0.959
SLC26A4	O43511-1.1	L471D	Pathogenic	0.992
SLC26A4	O43511-1.1	L471E	Pathogenic	0.993
SLC26A4	O43511-1.1	L471F	Pathogenic	0.98
SLC26A4	O43511-1.1	L471G	Pathogenic	0.959
SLC26A4	O43511-1.1	L471H	Pathogenic	0.997
SLC26A4	O43511-1.1	L471I	Pathogenic	0.953
SLC26A4	O43511-1.1	L471K	Pathogenic	0.987
SLC26A4	O43511-1.1	L471M	Pathogenic	0.946
SLC26A4	O43511-1.1	L471N	Pathogenic	0.988
SLC26A4	O43511-1.1	L471P	Pathogenic	0.99
SLC26A4	O43511-1.1	L471Q	Pathogenic	0.99
SLC26A4	O43511-1.1	L471R	Pathogenic	0.976
SLC26A4	O43511-1.1	L471S	Pathogenic	0.946
SLC26A4	O43511-1.1	L471T	Pathogenic	0.96
SLC26A4	O43511-1.1	L471V	Pathogenic	0.937
SLC26A4	O43511-1.1	L471W	Pathogenic	0.979
SLC26A4	O43511-1.1	L471Y	Pathogenic	0.983
SLC26A4	O43511-1.1	W472A	Pathogenic	0.999
SLC26A4	O43511-1.1	W472C	Pathogenic	0.999
SLC26A4	O43511-1.1	W472D	Pathogenic	1.0
SLC26A4	O43511-1.1	W472E	Pathogenic	1.0
SLC26A4	O43511-1.1	W472F	Pathogenic	1.0
SLC26A4	O43511-1.1	W472G	Pathogenic	0.995
SLC26A4	O43511-1.1	W472H	Pathogenic	1.0
SLC26A4	O43511-1.1	W472I	Pathogenic	1.0
SLC26A4	O43511-1.1	W472K	Pathogenic	1.0
SLC26A4	O43511-1.1	W472L	Pathogenic	1.0
SLC26A4	O43511-1.1	W472M	Pathogenic	1.0
SLC26A4	O43511-1.1	W472N	Pathogenic	1.0
SLC26A4	O43511-1.1	W472P	Pathogenic	1.0
SLC26A4	O43511-1.1	W472Q	Pathogenic	1.0
SLC26A4	O43511-1.1	W472R	Pathogenic	1.0
SLC26A4	O43511-1.1	W472S	Pathogenic	0.999
SLC26A4	O43511-1.1	W472T	Pathogenic	0.999
SLC26A4	O43511-1.1	W472V	Pathogenic	1.0
SLC26A4	O43511-1.1	W472Y	Pathogenic	0.999
SLC26A4	O43511-1.1	R473A	Pathogenic	0.884
SLC26A4	O43511-1.1	R473C	Pathogenic	0.982
SLC26A4	O43511-1.1	R473D	Pathogenic	0.986
SLC26A4	O43511-1.1	R473E	Pathogenic	0.973
SLC26A4	O43511-1.1	R473F	Pathogenic	0.997
SLC26A4	O43511-1.1	R473G	Pathogenic	0.88
SLC26A4	O43511-1.1	R473H	Pathogenic	0.976
SLC26A4	O43511-1.1	R473I	Pathogenic	0.996
SLC26A4	O43511-1.1	R473K	Pathogenic	0.971
SLC26A4	O43511-1.1	R473L	Pathogenic	0.992
SLC26A4	O43511-1.1	R473M	Pathogenic	0.986
SLC26A4	O43511-1.1	R473N	Pathogenic	0.952
SLC26A4	O43511-1.1	R473P	Pathogenic	0.974
SLC26A4	O43511-1.1	R473Q	Pathogenic	0.951
SLC26A4	O43511-1.1	R473S	Pathogenic	0.92
SLC26A4	O43511-1.1	R473T	Pathogenic	0.962
SLC26A4	O43511-1.1	R473V	Pathogenic	0.992
SLC26A4	O43511-1.1	R473W	Pathogenic	0.997
SLC26A4	O43511-1.1	R473Y	Pathogenic	0.997
SLC26A4	O43511-1.1	Q474A	Pathogenic	0.736
SLC26A4	O43511-1.1	Q474C	Pathogenic	0.953
SLC26A4	O43511-1.1	Q474D	Pathogenic	0.803
SLC26A4	O43511-1.1	Q474E	Pathogenic	0.705
SLC26A4	O43511-1.1	Q474F	Pathogenic	0.954
SLC26A4	O43511-1.1	Q474G	Pathogenic	0.728
SLC26A4	O43511-1.1	Q474H	Pathogenic	0.912
SLC26A4	O43511-1.1	Q474I	Pathogenic	0.971
SLC26A4	O43511-1.1	Q474K	Pathogenic	0.671
SLC26A4	O43511-1.1	Q474L	Pathogenic	0.946
SLC26A4	O43511-1.1	Q474M	Pathogenic	0.838
SLC26A4	O43511-1.1	Q474N	Pathogenic	0.845
SLC26A4	O43511-1.1	Q474P	Pathogenic	0.871
SLC26A4	O43511-1.1	Q474R	Pathogenic	0.53
SLC26A4	O43511-1.1	Q474S	Pathogenic	0.676
SLC26A4	O43511-1.1	Q474T	Pathogenic	0.902
SLC26A4	O43511-1.1	Q474V	Pathogenic	0.956
SLC26A4	O43511-1.1	Q474W	Pathogenic	0.708
SLC26A4	O43511-1.1	Q474Y	Pathogenic	0.843
SLC26A4	O43511-1.1	N475A	Pathogenic	0.926
SLC26A4	O43511-1.1	N475C	Pathogenic	0.979
SLC26A4	O43511-1.1	N475D	Pathogenic	0.859
SLC26A4	O43511-1.1	N475E	Pathogenic	0.9
SLC26A4	O43511-1.1	N475F	Pathogenic	0.901
SLC26A4	O43511-1.1	N475G	Pathogenic	0.599
SLC26A4	O43511-1.1	N475H	Pathogenic	0.695
SLC26A4	O43511-1.1	N475I	Pathogenic	0.937
SLC26A4	O43511-1.1	N475K	Pathogenic	0.709
SLC26A4	O43511-1.1	N475L	Pathogenic	0.939
SLC26A4	O43511-1.1	N475M	Pathogenic	0.902
SLC26A4	O43511-1.1	N475P	Pathogenic	0.968
SLC26A4	O43511-1.1	N475Q	Pathogenic	0.863
SLC26A4	O43511-1.1	N475R	Pathogenic	0.573
SLC26A4	O43511-1.1	N475S	Pathogenic	0.699
SLC26A4	O43511-1.1	N475T	Pathogenic	0.912
SLC26A4	O43511-1.1	N475V	Pathogenic	0.978
SLC26A4	O43511-1.1	N475W	Pathogenic	0.812
SLC26A4	O43511-1.1	N475Y	Pathogenic	0.826
SLC26A4	O43511-1.1	K476A	Pathogenic	0.94
SLC26A4	O43511-1.1	K476C	Pathogenic	0.991
SLC26A4	O43511-1.1	K476D	Pathogenic	0.986
SLC26A4	O43511-1.1	K476E	Pathogenic	0.974
SLC26A4	O43511-1.1	K476F	Pathogenic	0.999
SLC26A4	O43511-1.1	K476G	Pathogenic	0.937
SLC26A4	O43511-1.1	K476H	Pathogenic	0.994
SLC26A4	O43511-1.1	K476I	Pathogenic	0.998
SLC26A4	O43511-1.1	K476L	Pathogenic	0.996
SLC26A4	O43511-1.1	K476M	Pathogenic	0.993
SLC26A4	O43511-1.1	K476N	Pathogenic	0.976
SLC26A4	O43511-1.1	K476P	Pathogenic	0.974
SLC26A4	O43511-1.1	K476Q	Pathogenic	0.975
SLC26A4	O43511-1.1	K476R	Pathogenic	0.974
SLC26A4	O43511-1.1	K476S	Pathogenic	0.921
SLC26A4	O43511-1.1	K476T	Pathogenic	0.981
SLC26A4	O43511-1.1	K476V	Pathogenic	0.992
SLC26A4	O43511-1.1	K476W	Pathogenic	0.994
SLC26A4	O43511-1.1	K476Y	Pathogenic	0.998
SLC26A4	O43511-1.1	I477A	Neutral	0.008
SLC26A4	O43511-1.1	I477C	Neutral	0.025
SLC26A4	O43511-1.1	I477D	Neutral	0.062
SLC26A4	O43511-1.1	I477E	Neutral	0.136
SLC26A4	O43511-1.1	I477F	Neutral	0.056
SLC26A4	O43511-1.1	I477G	Neutral	0.025
SLC26A4	O43511-1.1	I477H	Neutral	0.241
SLC26A4	O43511-1.1	I477K	Neutral	0.141
SLC26A4	O43511-1.1	I477L	Neutral	0.023
SLC26A4	O43511-1.1	I477M	Neutral	0.037
SLC26A4	O43511-1.1	I477N	Neutral	0.081
SLC26A4	O43511-1.1	I477P	Neutral	0.101
SLC26A4	O43511-1.1	I477Q	Neutral	0.188
SLC26A4	O43511-1.1	I477R	Neutral	0.083
SLC26A4	O43511-1.1	I477S	Neutral	0.019
SLC26A4	O43511-1.1	I477T	Neutral	0.026
SLC26A4	O43511-1.1	I477V	Neutral	0.004
SLC26A4	O43511-1.1	I477W	Neutral	0.103
SLC26A4	O43511-1.1	I477Y	Neutral	0.062
SLC26A4	O43511-1.1	D478A	Pathogenic	0.997
SLC26A4	O43511-1.1	D478C	Pathogenic	0.999
SLC26A4	O43511-1.1	D478E	Pathogenic	0.976
SLC26A4	O43511-1.1	D478F	Pathogenic	0.994
SLC26A4	O43511-1.1	D478G	Pathogenic	0.988
SLC26A4	O43511-1.1	D478H	Pathogenic	0.994
SLC26A4	O43511-1.1	D478I	Pathogenic	0.996
SLC26A4	O43511-1.1	D478K	Pathogenic	0.99
SLC26A4	O43511-1.1	D478L	Pathogenic	0.998
SLC26A4	O43511-1.1	D478M	Pathogenic	0.997
SLC26A4	O43511-1.1	D478N	Pathogenic	0.993
SLC26A4	O43511-1.1	D478P	Pathogenic	0.998
SLC26A4	O43511-1.1	D478Q	Pathogenic	0.991
SLC26A4	O43511-1.1	D478R	Pathogenic	0.991
SLC26A4	O43511-1.1	D478S	Pathogenic	0.992
SLC26A4	O43511-1.1	D478T	Pathogenic	0.998
SLC26A4	O43511-1.1	D478V	Pathogenic	0.999
SLC26A4	O43511-1.1	D478W	Pathogenic	0.987
SLC26A4	O43511-1.1	D478Y	Pathogenic	0.994
SLC26A4	O43511-1.1	A479C	Pathogenic	0.565
SLC26A4	O43511-1.1	A479D	Pathogenic	0.781
SLC26A4	O43511-1.1	A479E	Neutral	0.454
SLC26A4	O43511-1.1	A479F	Neutral	0.296
SLC26A4	O43511-1.1	A479G	Pathogenic	0.599
SLC26A4	O43511-1.1	A479H	Pathogenic	0.599
SLC26A4	O43511-1.1	A479I	Neutral	0.255
SLC26A4	O43511-1.1	A479K	Neutral	0.183
SLC26A4	O43511-1.1	A479L	Neutral	0.262
SLC26A4	O43511-1.1	A479M	Neutral	0.299
SLC26A4	O43511-1.1	A479N	Pathogenic	0.753
SLC26A4	O43511-1.1	A479P	Pathogenic	0.707
SLC26A4	O43511-1.1	A479Q	Neutral	0.438
SLC26A4	O43511-1.1	A479R	Neutral	0.11
SLC26A4	O43511-1.1	A479S	Pathogenic	0.569
SLC26A4	O43511-1.1	A479T	Pathogenic	0.546
SLC26A4	O43511-1.1	A479V	Neutral	0.334
SLC26A4	O43511-1.1	A479W	Neutral	0.166
SLC26A4	O43511-1.1	A479Y	Neutral	0.306
SLC26A4	O43511-1.1	V480A	Neutral	0.14
SLC26A4	O43511-1.1	V480C	Pathogenic	0.5
SLC26A4	O43511-1.1	V480D	Pathogenic	0.721
SLC26A4	O43511-1.1	V480E	Pathogenic	0.68
SLC26A4	O43511-1.1	V480F	Neutral	0.349
SLC26A4	O43511-1.1	V480G	Neutral	0.333
SLC26A4	O43511-1.1	V480H	Pathogenic	0.793
SLC26A4	O43511-1.1	V480I	Neutral	0.051
SLC26A4	O43511-1.1	V480K	Neutral	0.364
SLC26A4	O43511-1.1	V480L	Neutral	0.184
SLC26A4	O43511-1.1	V480M	Neutral	0.213
SLC26A4	O43511-1.1	V480N	Pathogenic	0.775
SLC26A4	O43511-1.1	V480P	Pathogenic	0.685
SLC26A4	O43511-1.1	V480Q	Pathogenic	0.665
SLC26A4	O43511-1.1	V480R	Neutral	0.389
SLC26A4	O43511-1.1	V480S	Neutral	0.43
SLC26A4	O43511-1.1	V480T	Neutral	0.341
SLC26A4	O43511-1.1	V480W	Neutral	0.338
SLC26A4	O43511-1.1	V480Y	Neutral	0.316
SLC26A4	O43511-1.1	I481A	Pathogenic	0.887
SLC26A4	O43511-1.1	I481C	Pathogenic	0.96
SLC26A4	O43511-1.1	I481D	Pathogenic	0.984
SLC26A4	O43511-1.1	I481E	Pathogenic	0.993
SLC26A4	O43511-1.1	I481F	Pathogenic	0.982
SLC26A4	O43511-1.1	I481G	Pathogenic	0.96
SLC26A4	O43511-1.1	I481H	Pathogenic	0.997
SLC26A4	O43511-1.1	I481K	Pathogenic	0.993
SLC26A4	O43511-1.1	I481L	Pathogenic	0.956
SLC26A4	O43511-1.1	I481M	Pathogenic	0.973
SLC26A4	O43511-1.1	I481N	Pathogenic	0.988
SLC26A4	O43511-1.1	I481P	Pathogenic	0.991
SLC26A4	O43511-1.1	I481Q	Pathogenic	0.995
SLC26A4	O43511-1.1	I481R	Pathogenic	0.988
SLC26A4	O43511-1.1	I481S	Pathogenic	0.947
SLC26A4	O43511-1.1	I481T	Pathogenic	0.961
SLC26A4	O43511-1.1	I481V	Pathogenic	0.791
SLC26A4	O43511-1.1	I481W	Pathogenic	0.991
SLC26A4	O43511-1.1	I481Y	Pathogenic	0.984
SLC26A4	O43511-1.1	W482A	Pathogenic	0.999
SLC26A4	O43511-1.1	W482C	Pathogenic	0.999
SLC26A4	O43511-1.1	W482D	Pathogenic	1.0
SLC26A4	O43511-1.1	W482E	Pathogenic	1.0
SLC26A4	O43511-1.1	W482F	Pathogenic	1.0
SLC26A4	O43511-1.1	W482G	Pathogenic	0.996
SLC26A4	O43511-1.1	W482H	Pathogenic	1.0
SLC26A4	O43511-1.1	W482I	Pathogenic	1.0
SLC26A4	O43511-1.1	W482K	Pathogenic	1.0
SLC26A4	O43511-1.1	W482L	Pathogenic	1.0
SLC26A4	O43511-1.1	W482M	Pathogenic	1.0
SLC26A4	O43511-1.1	W482N	Pathogenic	1.0
SLC26A4	O43511-1.1	W482P	Pathogenic	1.0
SLC26A4	O43511-1.1	W482Q	Pathogenic	1.0
SLC26A4	O43511-1.1	W482R	Pathogenic	1.0
SLC26A4	O43511-1.1	W482S	Pathogenic	0.999
SLC26A4	O43511-1.1	W482T	Pathogenic	0.999
SLC26A4	O43511-1.1	W482V	Pathogenic	1.0
SLC26A4	O43511-1.1	W482Y	Pathogenic	0.999
SLC26A4	O43511-1.1	V483A	Pathogenic	0.61
SLC26A4	O43511-1.1	V483C	Pathogenic	0.906
SLC26A4	O43511-1.1	V483D	Pathogenic	0.961
SLC26A4	O43511-1.1	V483E	Pathogenic	0.953
SLC26A4	O43511-1.1	V483F	Pathogenic	0.837
SLC26A4	O43511-1.1	V483G	Pathogenic	0.827
SLC26A4	O43511-1.1	V483H	Pathogenic	0.973
SLC26A4	O43511-1.1	V483I	Neutral	0.34
SLC26A4	O43511-1.1	V483K	Pathogenic	0.846
SLC26A4	O43511-1.1	V483L	Pathogenic	0.684
SLC26A4	O43511-1.1	V483M	Pathogenic	0.722
SLC26A4	O43511-1.1	V483N	Pathogenic	0.971
SLC26A4	O43511-1.1	V483P	Pathogenic	0.954
SLC26A4	O43511-1.1	V483Q	Pathogenic	0.95
SLC26A4	O43511-1.1	V483R	Pathogenic	0.859
SLC26A4	O43511-1.1	V483S	Pathogenic	0.879
SLC26A4	O43511-1.1	V483T	Pathogenic	0.832
SLC26A4	O43511-1.1	V483W	Pathogenic	0.831
SLC26A4	O43511-1.1	V483Y	Pathogenic	0.816
SLC26A4	O43511-1.1	F484A	Neutral	0.212
SLC26A4	O43511-1.1	F484C	Neutral	0.452
SLC26A4	O43511-1.1	F484D	Pathogenic	0.514
SLC26A4	O43511-1.1	F484E	Pathogenic	0.715
SLC26A4	O43511-1.1	F484G	Neutral	0.169
SLC26A4	O43511-1.1	F484H	Pathogenic	0.556
SLC26A4	O43511-1.1	F484I	Pathogenic	0.606
SLC26A4	O43511-1.1	F484K	Pathogenic	0.876
SLC26A4	O43511-1.1	F484L	Pathogenic	0.6
SLC26A4	O43511-1.1	F484M	Pathogenic	0.555
SLC26A4	O43511-1.1	F484N	Pathogenic	0.585
SLC26A4	O43511-1.1	F484P	Pathogenic	0.783
SLC26A4	O43511-1.1	F484Q	Pathogenic	0.787
SLC26A4	O43511-1.1	F484R	Pathogenic	0.796
SLC26A4	O43511-1.1	F484S	Neutral	0.236
SLC26A4	O43511-1.1	F484T	Neutral	0.461
SLC26A4	O43511-1.1	F484V	Pathogenic	0.514
SLC26A4	O43511-1.1	F484W	Neutral	0.23
SLC26A4	O43511-1.1	F484Y	Neutral	0.148
SLC26A4	O43511-1.1	T485A	Pathogenic	0.985
SLC26A4	O43511-1.1	T485C	Pathogenic	0.996
SLC26A4	O43511-1.1	T485D	Pathogenic	0.996
SLC26A4	O43511-1.1	T485E	Pathogenic	0.993
SLC26A4	O43511-1.1	T485F	Pathogenic	0.986
SLC26A4	O43511-1.1	T485G	Pathogenic	0.99
SLC26A4	O43511-1.1	T485H	Pathogenic	0.996
SLC26A4	O43511-1.1	T485I	Pathogenic	0.983
SLC26A4	O43511-1.1	T485K	Pathogenic	0.975
SLC26A4	O43511-1.1	T485L	Pathogenic	0.984
SLC26A4	O43511-1.1	T485M	Pathogenic	0.986
SLC26A4	O43511-1.1	T485N	Pathogenic	0.993
SLC26A4	O43511-1.1	T485P	Pathogenic	0.997
SLC26A4	O43511-1.1	T485Q	Pathogenic	0.993
SLC26A4	O43511-1.1	T485R	Pathogenic	0.956
SLC26A4	O43511-1.1	T485S	Pathogenic	0.974
SLC26A4	O43511-1.1	T485V	Pathogenic	0.988
SLC26A4	O43511-1.1	T485W	Pathogenic	0.944
SLC26A4	O43511-1.1	T485Y	Pathogenic	0.987
SLC26A4	O43511-1.1	C486A	Pathogenic	0.99
SLC26A4	O43511-1.1	C486D	Pathogenic	0.999
SLC26A4	O43511-1.1	C486E	Pathogenic	0.999
SLC26A4	O43511-1.1	C486F	Pathogenic	0.99
SLC26A4	O43511-1.1	C486G	Pathogenic	0.997
SLC26A4	O43511-1.1	C486H	Pathogenic	0.998
SLC26A4	O43511-1.1	C486I	Pathogenic	0.988
SLC26A4	O43511-1.1	C486K	Pathogenic	0.992
SLC26A4	O43511-1.1	C486L	Pathogenic	0.988
SLC26A4	O43511-1.1	C486M	Pathogenic	0.99
SLC26A4	O43511-1.1	C486N	Pathogenic	0.999
SLC26A4	O43511-1.1	C486P	Pathogenic	0.999
SLC26A4	O43511-1.1	C486Q	Pathogenic	0.998
SLC26A4	O43511-1.1	C486R	Pathogenic	0.986
SLC26A4	O43511-1.1	C486S	Pathogenic	0.996
SLC26A4	O43511-1.1	C486T	Pathogenic	0.997
SLC26A4	O43511-1.1	C486V	Pathogenic	0.996
SLC26A4	O43511-1.1	C486W	Pathogenic	0.959
SLC26A4	O43511-1.1	C486Y	Pathogenic	0.99
SLC26A4	O43511-1.1	I487A	Neutral	0.077
SLC26A4	O43511-1.1	I487C	Neutral	0.204
SLC26A4	O43511-1.1	I487D	Neutral	0.398
SLC26A4	O43511-1.1	I487E	Pathogenic	0.61
SLC26A4	O43511-1.1	I487F	Neutral	0.371
SLC26A4	O43511-1.1	I487G	Neutral	0.204
SLC26A4	O43511-1.1	I487H	Pathogenic	0.76
SLC26A4	O43511-1.1	I487K	Pathogenic	0.621
SLC26A4	O43511-1.1	I487L	Neutral	0.188
SLC26A4	O43511-1.1	I487M	Neutral	0.28
SLC26A4	O43511-1.1	I487N	Neutral	0.469
SLC26A4	O43511-1.1	I487P	Pathogenic	0.528
SLC26A4	O43511-1.1	I487Q	Pathogenic	0.697
SLC26A4	O43511-1.1	I487R	Neutral	0.475
SLC26A4	O43511-1.1	I487S	Neutral	0.162
SLC26A4	O43511-1.1	I487T	Neutral	0.21
SLC26A4	O43511-1.1	I487V	Neutral	0.039
SLC26A4	O43511-1.1	I487W	Pathogenic	0.533
SLC26A4	O43511-1.1	I487Y	Neutral	0.396
SLC26A4	O43511-1.1	V488A	Neutral	0.005
SLC26A4	O43511-1.1	V488C	Neutral	0.032
SLC26A4	O43511-1.1	V488D	Neutral	0.079
SLC26A4	O43511-1.1	V488E	Neutral	0.066
SLC26A4	O43511-1.1	V488F	Neutral	0.017
SLC26A4	O43511-1.1	V488G	Neutral	0.016
SLC26A4	O43511-1.1	V488H	Neutral	0.112
SLC26A4	O43511-1.1	V488I	Neutral	0.002
SLC26A4	O43511-1.1	V488K	Neutral	0.019
SLC26A4	O43511-1.1	V488L	Neutral	0.007
SLC26A4	O43511-1.1	V488M	Neutral	0.009
SLC26A4	O43511-1.1	V488N	Neutral	0.102
SLC26A4	O43511-1.1	V488P	Neutral	0.067
SLC26A4	O43511-1.1	V488Q	Neutral	0.062
SLC26A4	O43511-1.1	V488R	Neutral	0.021
SLC26A4	O43511-1.1	V488S	Neutral	0.024
SLC26A4	O43511-1.1	V488T	Neutral	0.017
SLC26A4	O43511-1.1	V488W	Neutral	0.017
SLC26A4	O43511-1.1	V488Y	Neutral	0.015
SLC26A4	O43511-1.1	S489A	Pathogenic	0.719
SLC26A4	O43511-1.1	S489C	Pathogenic	0.853
SLC26A4	O43511-1.1	S489D	Pathogenic	0.72
SLC26A4	O43511-1.1	S489E	Pathogenic	0.546
SLC26A4	O43511-1.1	S489F	Neutral	0.483
SLC26A4	O43511-1.1	S489G	Pathogenic	0.711
SLC26A4	O43511-1.1	S489H	Pathogenic	0.655
SLC26A4	O43511-1.1	S489I	Pathogenic	0.605
SLC26A4	O43511-1.1	S489K	Neutral	0.245
SLC26A4	O43511-1.1	S489L	Pathogenic	0.614
SLC26A4	O43511-1.1	S489M	Neutral	0.487
SLC26A4	O43511-1.1	S489N	Pathogenic	0.522
SLC26A4	O43511-1.1	S489P	Pathogenic	0.843
SLC26A4	O43511-1.1	S489Q	Pathogenic	0.53
SLC26A4	O43511-1.1	S489R	Neutral	0.265
SLC26A4	O43511-1.1	S489T	Pathogenic	0.581
SLC26A4	O43511-1.1	S489V	Pathogenic	0.819
SLC26A4	O43511-1.1	S489W	Neutral	0.308
SLC26A4	O43511-1.1	S489Y	Neutral	0.496
SLC26A4	O43511-1.1	I490A	Neutral	0.365
SLC26A4	O43511-1.1	I490C	Pathogenic	0.637
SLC26A4	O43511-1.1	I490D	Pathogenic	0.819
SLC26A4	O43511-1.1	I490E	Pathogenic	0.915
SLC26A4	O43511-1.1	I490F	Pathogenic	0.801
SLC26A4	O43511-1.1	I490G	Pathogenic	0.637
SLC26A4	O43511-1.1	I490H	Pathogenic	0.956
SLC26A4	O43511-1.1	I490K	Pathogenic	0.918
SLC26A4	O43511-1.1	I490L	Pathogenic	0.613
SLC26A4	O43511-1.1	I490M	Pathogenic	0.727
SLC26A4	O43511-1.1	I490N	Pathogenic	0.858
SLC26A4	O43511-1.1	I490P	Pathogenic	0.884
SLC26A4	O43511-1.1	I490Q	Pathogenic	0.94
SLC26A4	O43511-1.1	I490R	Pathogenic	0.861
SLC26A4	O43511-1.1	I490S	Pathogenic	0.569
SLC26A4	O43511-1.1	I490T	Pathogenic	0.645
SLC26A4	O43511-1.1	I490V	Neutral	0.217
SLC26A4	O43511-1.1	I490W	Pathogenic	0.887
SLC26A4	O43511-1.1	I490Y	Pathogenic	0.818
SLC26A4	O43511-1.1	I491A	Neutral	0.086
SLC26A4	O43511-1.1	I491C	Neutral	0.223
SLC26A4	O43511-1.1	I491D	Neutral	0.424
SLC26A4	O43511-1.1	I491E	Pathogenic	0.636
SLC26A4	O43511-1.1	I491F	Neutral	0.397
SLC26A4	O43511-1.1	I491G	Neutral	0.222
SLC26A4	O43511-1.1	I491H	Pathogenic	0.779
SLC26A4	O43511-1.1	I491K	Pathogenic	0.646
SLC26A4	O43511-1.1	I491L	Neutral	0.206
SLC26A4	O43511-1.1	I491M	Neutral	0.303
SLC26A4	O43511-1.1	I491N	Neutral	0.496
SLC26A4	O43511-1.1	I491P	Pathogenic	0.556
SLC26A4	O43511-1.1	I491Q	Pathogenic	0.72
SLC26A4	O43511-1.1	I491R	Pathogenic	0.503
SLC26A4	O43511-1.1	I491S	Neutral	0.178
SLC26A4	O43511-1.1	I491T	Neutral	0.229
SLC26A4	O43511-1.1	I491V	Neutral	0.043
SLC26A4	O43511-1.1	I491W	Pathogenic	0.561
SLC26A4	O43511-1.1	I491Y	Neutral	0.423
SLC26A4	O43511-1.1	L492A	Pathogenic	0.927
SLC26A4	O43511-1.1	L492C	Pathogenic	0.975
SLC26A4	O43511-1.1	L492D	Pathogenic	0.995
SLC26A4	O43511-1.1	L492E	Pathogenic	0.996
SLC26A4	O43511-1.1	L492F	Pathogenic	0.988
SLC26A4	O43511-1.1	L492G	Pathogenic	0.975
SLC26A4	O43511-1.1	L492H	Pathogenic	0.998
SLC26A4	O43511-1.1	L492I	Pathogenic	0.971
SLC26A4	O43511-1.1	L492K	Pathogenic	0.992
SLC26A4	O43511-1.1	L492M	Pathogenic	0.967
SLC26A4	O43511-1.1	L492N	Pathogenic	0.993
SLC26A4	O43511-1.1	L492P	Pathogenic	0.994
SLC26A4	O43511-1.1	L492Q	Pathogenic	0.994
SLC26A4	O43511-1.1	L492R	Pathogenic	0.986
SLC26A4	O43511-1.1	L492S	Pathogenic	0.967
SLC26A4	O43511-1.1	L492T	Pathogenic	0.976
SLC26A4	O43511-1.1	L492V	Pathogenic	0.961
SLC26A4	O43511-1.1	L492W	Pathogenic	0.988
SLC26A4	O43511-1.1	L492Y	Pathogenic	0.99
SLC26A4	O43511-1.1	G493A	Pathogenic	0.993
SLC26A4	O43511-1.1	G493C	Pathogenic	0.997
SLC26A4	O43511-1.1	G493D	Pathogenic	0.988
SLC26A4	O43511-1.1	G493E	Pathogenic	0.987
SLC26A4	O43511-1.1	G493F	Pathogenic	0.968
SLC26A4	O43511-1.1	G493H	Pathogenic	0.984
SLC26A4	O43511-1.1	G493I	Pathogenic	0.99
SLC26A4	O43511-1.1	G493K	Pathogenic	0.953
SLC26A4	O43511-1.1	G493L	Pathogenic	0.99
SLC26A4	O43511-1.1	G493M	Pathogenic	0.984
SLC26A4	O43511-1.1	G493N	Pathogenic	0.971
SLC26A4	O43511-1.1	G493P	Pathogenic	0.994
SLC26A4	O43511-1.1	G493Q	Pathogenic	0.986
SLC26A4	O43511-1.1	G493R	Pathogenic	0.918
SLC26A4	O43511-1.1	G493S	Pathogenic	0.992
SLC26A4	O43511-1.1	G493T	Pathogenic	0.994
SLC26A4	O43511-1.1	G493V	Pathogenic	0.993
SLC26A4	O43511-1.1	G493W	Pathogenic	0.778
SLC26A4	O43511-1.1	G493Y	Pathogenic	0.969
SLC26A4	O43511-1.1	L494A	Pathogenic	0.927
SLC26A4	O43511-1.1	L494C	Pathogenic	0.975
SLC26A4	O43511-1.1	L494D	Pathogenic	0.995
SLC26A4	O43511-1.1	L494E	Pathogenic	0.996
SLC26A4	O43511-1.1	L494F	Pathogenic	0.988
SLC26A4	O43511-1.1	L494G	Pathogenic	0.975
SLC26A4	O43511-1.1	L494H	Pathogenic	0.998
SLC26A4	O43511-1.1	L494I	Pathogenic	0.971
SLC26A4	O43511-1.1	L494K	Pathogenic	0.992
SLC26A4	O43511-1.1	L494M	Pathogenic	0.967
SLC26A4	O43511-1.1	L494N	Pathogenic	0.993
SLC26A4	O43511-1.1	L494P	Pathogenic	0.994
SLC26A4	O43511-1.1	L494Q	Pathogenic	0.994
SLC26A4	O43511-1.1	L494R	Pathogenic	0.986
SLC26A4	O43511-1.1	L494S	Pathogenic	0.967
SLC26A4	O43511-1.1	L494T	Pathogenic	0.976
SLC26A4	O43511-1.1	L494V	Pathogenic	0.961
SLC26A4	O43511-1.1	L494W	Pathogenic	0.988
SLC26A4	O43511-1.1	L494Y	Pathogenic	0.99
SLC26A4	O43511-1.1	D495A	Pathogenic	0.988
SLC26A4	O43511-1.1	D495C	Pathogenic	0.997
SLC26A4	O43511-1.1	D495E	Pathogenic	0.902
SLC26A4	O43511-1.1	D495F	Pathogenic	0.973
SLC26A4	O43511-1.1	D495G	Pathogenic	0.95
SLC26A4	O43511-1.1	D495H	Pathogenic	0.974
SLC26A4	O43511-1.1	D495I	Pathogenic	0.984
SLC26A4	O43511-1.1	D495K	Pathogenic	0.957
SLC26A4	O43511-1.1	D495L	Pathogenic	0.992
SLC26A4	O43511-1.1	D495M	Pathogenic	0.987
SLC26A4	O43511-1.1	D495N	Pathogenic	0.97
SLC26A4	O43511-1.1	D495P	Pathogenic	0.99
SLC26A4	O43511-1.1	D495Q	Pathogenic	0.962
SLC26A4	O43511-1.1	D495R	Pathogenic	0.961
SLC26A4	O43511-1.1	D495S	Pathogenic	0.967
SLC26A4	O43511-1.1	D495T	Pathogenic	0.991
SLC26A4	O43511-1.1	D495V	Pathogenic	0.994
SLC26A4	O43511-1.1	D495W	Pathogenic	0.946
SLC26A4	O43511-1.1	D495Y	Pathogenic	0.975
SLC26A4	O43511-1.1	L496A	Neutral	0.451
SLC26A4	O43511-1.1	L496C	Pathogenic	0.715
SLC26A4	O43511-1.1	L496D	Pathogenic	0.928
SLC26A4	O43511-1.1	L496E	Pathogenic	0.939
SLC26A4	O43511-1.1	L496F	Pathogenic	0.843
SLC26A4	O43511-1.1	L496G	Pathogenic	0.715
SLC26A4	O43511-1.1	L496H	Pathogenic	0.969
SLC26A4	O43511-1.1	L496I	Pathogenic	0.686
SLC26A4	O43511-1.1	L496K	Pathogenic	0.889
SLC26A4	O43511-1.1	L496M	Pathogenic	0.654
SLC26A4	O43511-1.1	L496N	Pathogenic	0.896
SLC26A4	O43511-1.1	L496P	Pathogenic	0.916
SLC26A4	O43511-1.1	L496Q	Pathogenic	0.918
SLC26A4	O43511-1.1	L496R	Pathogenic	0.815
SLC26A4	O43511-1.1	L496S	Pathogenic	0.654
SLC26A4	O43511-1.1	L496T	Pathogenic	0.722
SLC26A4	O43511-1.1	L496V	Pathogenic	0.616
SLC26A4	O43511-1.1	L496W	Pathogenic	0.837
SLC26A4	O43511-1.1	L496Y	Pathogenic	0.865
SLC26A4	O43511-1.1	G497A	Pathogenic	0.993
SLC26A4	O43511-1.1	G497C	Pathogenic	0.997
SLC26A4	O43511-1.1	G497D	Pathogenic	0.988
SLC26A4	O43511-1.1	G497E	Pathogenic	0.987
SLC26A4	O43511-1.1	G497F	Pathogenic	0.968
SLC26A4	O43511-1.1	G497H	Pathogenic	0.984
SLC26A4	O43511-1.1	G497I	Pathogenic	0.99
SLC26A4	O43511-1.1	G497K	Pathogenic	0.953
SLC26A4	O43511-1.1	G497L	Pathogenic	0.99
SLC26A4	O43511-1.1	G497M	Pathogenic	0.984
SLC26A4	O43511-1.1	G497N	Pathogenic	0.971
SLC26A4	O43511-1.1	G497P	Pathogenic	0.994
SLC26A4	O43511-1.1	G497Q	Pathogenic	0.986
SLC26A4	O43511-1.1	G497R	Pathogenic	0.918
SLC26A4	O43511-1.1	G497S	Pathogenic	0.992
SLC26A4	O43511-1.1	G497T	Pathogenic	0.994
SLC26A4	O43511-1.1	G497V	Pathogenic	0.993
SLC26A4	O43511-1.1	G497W	Pathogenic	0.778
SLC26A4	O43511-1.1	G497Y	Pathogenic	0.969
SLC26A4	O43511-1.1	L498A	Pathogenic	0.927
SLC26A4	O43511-1.1	L498C	Pathogenic	0.975
SLC26A4	O43511-1.1	L498D	Pathogenic	0.995
SLC26A4	O43511-1.1	L498E	Pathogenic	0.996
SLC26A4	O43511-1.1	L498F	Pathogenic	0.988
SLC26A4	O43511-1.1	L498G	Pathogenic	0.975
SLC26A4	O43511-1.1	L498H	Pathogenic	0.998
SLC26A4	O43511-1.1	L498I	Pathogenic	0.971
SLC26A4	O43511-1.1	L498K	Pathogenic	0.992
SLC26A4	O43511-1.1	L498M	Pathogenic	0.967
SLC26A4	O43511-1.1	L498N	Pathogenic	0.993
SLC26A4	O43511-1.1	L498P	Pathogenic	0.994
SLC26A4	O43511-1.1	L498Q	Pathogenic	0.994
SLC26A4	O43511-1.1	L498R	Pathogenic	0.986
SLC26A4	O43511-1.1	L498S	Pathogenic	0.967
SLC26A4	O43511-1.1	L498T	Pathogenic	0.976
SLC26A4	O43511-1.1	L498V	Pathogenic	0.961
SLC26A4	O43511-1.1	L498W	Pathogenic	0.988
SLC26A4	O43511-1.1	L498Y	Pathogenic	0.99
SLC26A4	O43511-1.1	L499A	Neutral	0.286
SLC26A4	O43511-1.1	L499C	Pathogenic	0.55
SLC26A4	O43511-1.1	L499D	Pathogenic	0.864
SLC26A4	O43511-1.1	L499E	Pathogenic	0.882
SLC26A4	O43511-1.1	L499F	Pathogenic	0.724
SLC26A4	O43511-1.1	L499G	Pathogenic	0.55
SLC26A4	O43511-1.1	L499H	Pathogenic	0.938
SLC26A4	O43511-1.1	L499I	Pathogenic	0.515
SLC26A4	O43511-1.1	L499K	Pathogenic	0.795
SLC26A4	O43511-1.1	L499M	Neutral	0.48
SLC26A4	O43511-1.1	L499N	Pathogenic	0.808
SLC26A4	O43511-1.1	L499P	Pathogenic	0.842
SLC26A4	O43511-1.1	L499Q	Pathogenic	0.846
SLC26A4	O43511-1.1	L499R	Pathogenic	0.683
SLC26A4	O43511-1.1	L499S	Neutral	0.48
SLC26A4	O43511-1.1	L499T	Pathogenic	0.559
SLC26A4	O43511-1.1	L499V	Neutral	0.439
SLC26A4	O43511-1.1	L499W	Pathogenic	0.715
SLC26A4	O43511-1.1	L499Y	Pathogenic	0.758
SLC26A4	O43511-1.1	A500C	Pathogenic	0.809
SLC26A4	O43511-1.1	A500D	Pathogenic	0.921
SLC26A4	O43511-1.1	A500E	Pathogenic	0.73
SLC26A4	O43511-1.1	A500F	Pathogenic	0.578
SLC26A4	O43511-1.1	A500G	Pathogenic	0.83
SLC26A4	O43511-1.1	A500H	Pathogenic	0.83
SLC26A4	O43511-1.1	A500I	Pathogenic	0.527
SLC26A4	O43511-1.1	A500K	Neutral	0.423
SLC26A4	O43511-1.1	A500L	Pathogenic	0.537
SLC26A4	O43511-1.1	A500M	Pathogenic	0.581
SLC26A4	O43511-1.1	A500N	Pathogenic	0.908
SLC26A4	O43511-1.1	A500P	Pathogenic	0.887
SLC26A4	O43511-1.1	A500Q	Pathogenic	0.718
SLC26A4	O43511-1.1	A500R	Neutral	0.288
SLC26A4	O43511-1.1	A500S	Pathogenic	0.811
SLC26A4	O43511-1.1	A500T	Pathogenic	0.797
SLC26A4	O43511-1.1	A500V	Pathogenic	0.621
SLC26A4	O43511-1.1	A500W	Neutral	0.394
SLC26A4	O43511-1.1	A500Y	Pathogenic	0.59
SLC26A4	O43511-1.1	G501A	Pathogenic	0.737
SLC26A4	O43511-1.1	G501C	Pathogenic	0.882
SLC26A4	O43511-1.1	G501D	Pathogenic	0.615
SLC26A4	O43511-1.1	G501E	Pathogenic	0.6
SLC26A4	O43511-1.1	G501F	Neutral	0.374
SLC26A4	O43511-1.1	G501H	Pathogenic	0.548
SLC26A4	O43511-1.1	G501I	Pathogenic	0.662
SLC26A4	O43511-1.1	G501K	Neutral	0.288
SLC26A4	O43511-1.1	G501L	Pathogenic	0.671
SLC26A4	O43511-1.1	G501M	Pathogenic	0.549
SLC26A4	O43511-1.1	G501N	Neutral	0.404
SLC26A4	O43511-1.1	G501P	Pathogenic	0.774
SLC26A4	O43511-1.1	G501Q	Pathogenic	0.584
SLC26A4	O43511-1.1	G501R	Neutral	0.183
SLC26A4	O43511-1.1	G501S	Pathogenic	0.704
SLC26A4	O43511-1.1	G501T	Pathogenic	0.781
SLC26A4	O43511-1.1	G501V	Pathogenic	0.743
SLC26A4	O43511-1.1	G501W	Neutral	0.066
SLC26A4	O43511-1.1	G501Y	Neutral	0.385
SLC26A4	O43511-1.1	L502A	Neutral	0.3
SLC26A4	O43511-1.1	L502C	Pathogenic	0.567
SLC26A4	O43511-1.1	L502D	Pathogenic	0.871
SLC26A4	O43511-1.1	L502E	Pathogenic	0.889
SLC26A4	O43511-1.1	L502F	Pathogenic	0.738
SLC26A4	O43511-1.1	L502G	Pathogenic	0.567
SLC26A4	O43511-1.1	L502H	Pathogenic	0.942
SLC26A4	O43511-1.1	L502I	Pathogenic	0.532
SLC26A4	O43511-1.1	L502K	Pathogenic	0.806
SLC26A4	O43511-1.1	L502M	Neutral	0.497
SLC26A4	O43511-1.1	L502N	Pathogenic	0.818
SLC26A4	O43511-1.1	L502P	Pathogenic	0.851
SLC26A4	O43511-1.1	L502Q	Pathogenic	0.854
SLC26A4	O43511-1.1	L502R	Pathogenic	0.697
SLC26A4	O43511-1.1	L502S	Neutral	0.497
SLC26A4	O43511-1.1	L502T	Pathogenic	0.576
SLC26A4	O43511-1.1	L502V	Neutral	0.456
SLC26A4	O43511-1.1	L502W	Pathogenic	0.728
SLC26A4	O43511-1.1	L502Y	Pathogenic	0.77
SLC26A4	O43511-1.1	I503A	Neutral	0.001
SLC26A4	O43511-1.1	I503C	Neutral	0.004
SLC26A4	O43511-1.1	I503D	Neutral	0.011
SLC26A4	O43511-1.1	I503E	Neutral	0.025
SLC26A4	O43511-1.1	I503F	Neutral	0.01
SLC26A4	O43511-1.1	I503G	Neutral	0.004
SLC26A4	O43511-1.1	I503H	Neutral	0.05
SLC26A4	O43511-1.1	I503K	Neutral	0.026
SLC26A4	O43511-1.1	I503L	Neutral	0.004
SLC26A4	O43511-1.1	I503M	Neutral	0.006
SLC26A4	O43511-1.1	I503N	Neutral	0.014
SLC26A4	O43511-1.1	I503P	Neutral	0.018
SLC26A4	O43511-1.1	I503Q	Neutral	0.037
SLC26A4	O43511-1.1	I503R	Neutral	0.015
SLC26A4	O43511-1.1	I503S	Neutral	0.003
SLC26A4	O43511-1.1	I503T	Neutral	0.004
SLC26A4	O43511-1.1	I503V	Neutral	0.001
SLC26A4	O43511-1.1	I503W	Neutral	0.019
SLC26A4	O43511-1.1	I503Y	Neutral	0.011
SLC26A4	O43511-1.1	F504A	Pathogenic	0.934
SLC26A4	O43511-1.1	F504C	Pathogenic	0.977
SLC26A4	O43511-1.1	F504D	Pathogenic	0.982
SLC26A4	O43511-1.1	F504E	Pathogenic	0.992
SLC26A4	O43511-1.1	F504G	Pathogenic	0.915
SLC26A4	O43511-1.1	F504H	Pathogenic	0.985
SLC26A4	O43511-1.1	F504I	Pathogenic	0.988
SLC26A4	O43511-1.1	F504K	Pathogenic	0.997
SLC26A4	O43511-1.1	F504L	Pathogenic	0.987
SLC26A4	O43511-1.1	F504M	Pathogenic	0.985
SLC26A4	O43511-1.1	F504N	Pathogenic	0.987
SLC26A4	O43511-1.1	F504P	Pathogenic	0.995
SLC26A4	O43511-1.1	F504Q	Pathogenic	0.995
SLC26A4	O43511-1.1	F504R	Pathogenic	0.995
SLC26A4	O43511-1.1	F504S	Pathogenic	0.942
SLC26A4	O43511-1.1	F504T	Pathogenic	0.978
SLC26A4	O43511-1.1	F504V	Pathogenic	0.982
SLC26A4	O43511-1.1	F504W	Pathogenic	0.94
SLC26A4	O43511-1.1	F504Y	Pathogenic	0.901
SLC26A4	O43511-1.1	G505A	Neutral	0.417
SLC26A4	O43511-1.1	G505C	Pathogenic	0.655
SLC26A4	O43511-1.1	G505D	Neutral	0.289
SLC26A4	O43511-1.1	G505E	Neutral	0.276
SLC26A4	O43511-1.1	G505F	Neutral	0.132
SLC26A4	O43511-1.1	G505H	Neutral	0.236
SLC26A4	O43511-1.1	G505I	Neutral	0.333
SLC26A4	O43511-1.1	G505K	Neutral	0.094
SLC26A4	O43511-1.1	G505L	Neutral	0.342
SLC26A4	O43511-1.1	G505M	Neutral	0.237
SLC26A4	O43511-1.1	G505N	Neutral	0.147
SLC26A4	O43511-1.1	G505P	Neutral	0.466
SLC26A4	O43511-1.1	G505Q	Neutral	0.264
SLC26A4	O43511-1.1	G505R	Neutral	0.054
SLC26A4	O43511-1.1	G505S	Neutral	0.377
SLC26A4	O43511-1.1	G505T	Neutral	0.477
SLC26A4	O43511-1.1	G505V	Neutral	0.424
SLC26A4	O43511-1.1	G505W	Neutral	0.018
SLC26A4	O43511-1.1	G505Y	Neutral	0.138
SLC26A4	O43511-1.1	L506A	Pathogenic	0.631
SLC26A4	O43511-1.1	L506C	Pathogenic	0.839
SLC26A4	O43511-1.1	L506D	Pathogenic	0.964
SLC26A4	O43511-1.1	L506E	Pathogenic	0.97
SLC26A4	O43511-1.1	L506F	Pathogenic	0.918
SLC26A4	O43511-1.1	L506G	Pathogenic	0.839
SLC26A4	O43511-1.1	L506H	Pathogenic	0.985
SLC26A4	O43511-1.1	L506I	Pathogenic	0.82
SLC26A4	O43511-1.1	L506K	Pathogenic	0.943
SLC26A4	O43511-1.1	L506M	Pathogenic	0.798
SLC26A4	O43511-1.1	L506N	Pathogenic	0.947
SLC26A4	O43511-1.1	L506P	Pathogenic	0.958
SLC26A4	O43511-1.1	L506Q	Pathogenic	0.959
SLC26A4	O43511-1.1	L506R	Pathogenic	0.902
SLC26A4	O43511-1.1	L506S	Pathogenic	0.798
SLC26A4	O43511-1.1	L506T	Pathogenic	0.844
SLC26A4	O43511-1.1	L506V	Pathogenic	0.77
SLC26A4	O43511-1.1	L506W	Pathogenic	0.915
SLC26A4	O43511-1.1	L506Y	Pathogenic	0.93
SLC26A4	O43511-1.1	L507A	Pathogenic	0.662
SLC26A4	O43511-1.1	L507C	Pathogenic	0.857
SLC26A4	O43511-1.1	L507D	Pathogenic	0.969
SLC26A4	O43511-1.1	L507E	Pathogenic	0.973
SLC26A4	O43511-1.1	L507F	Pathogenic	0.928
SLC26A4	O43511-1.1	L507G	Pathogenic	0.857
SLC26A4	O43511-1.1	L507H	Pathogenic	0.987
SLC26A4	O43511-1.1	L507I	Pathogenic	0.839
SLC26A4	O43511-1.1	L507K	Pathogenic	0.95
SLC26A4	O43511-1.1	L507M	Pathogenic	0.819
SLC26A4	O43511-1.1	L507N	Pathogenic	0.954
SLC26A4	O43511-1.1	L507P	Pathogenic	0.963
SLC26A4	O43511-1.1	L507Q	Pathogenic	0.964
SLC26A4	O43511-1.1	L507R	Pathogenic	0.913
SLC26A4	O43511-1.1	L507S	Pathogenic	0.819
SLC26A4	O43511-1.1	L507T	Pathogenic	0.861
SLC26A4	O43511-1.1	L507V	Pathogenic	0.793
SLC26A4	O43511-1.1	L507W	Pathogenic	0.925
SLC26A4	O43511-1.1	L507Y	Pathogenic	0.939
SLC26A4	O43511-1.1	T508A	Pathogenic	0.991
SLC26A4	O43511-1.1	T508C	Pathogenic	0.997
SLC26A4	O43511-1.1	T508D	Pathogenic	0.998
SLC26A4	O43511-1.1	T508E	Pathogenic	0.996
SLC26A4	O43511-1.1	T508F	Pathogenic	0.991
SLC26A4	O43511-1.1	T508G	Pathogenic	0.994
SLC26A4	O43511-1.1	T508H	Pathogenic	0.998
SLC26A4	O43511-1.1	T508I	Pathogenic	0.99
SLC26A4	O43511-1.1	T508K	Pathogenic	0.985
SLC26A4	O43511-1.1	T508L	Pathogenic	0.99
SLC26A4	O43511-1.1	T508M	Pathogenic	0.992
SLC26A4	O43511-1.1	T508N	Pathogenic	0.995
SLC26A4	O43511-1.1	T508P	Pathogenic	0.998
SLC26A4	O43511-1.1	T508Q	Pathogenic	0.996
SLC26A4	O43511-1.1	T508R	Pathogenic	0.973
SLC26A4	O43511-1.1	T508S	Pathogenic	0.984
SLC26A4	O43511-1.1	T508V	Pathogenic	0.993
SLC26A4	O43511-1.1	T508W	Pathogenic	0.965
SLC26A4	O43511-1.1	T508Y	Pathogenic	0.992
SLC26A4	O43511-1.1	V509A	Pathogenic	0.782
SLC26A4	O43511-1.1	V509C	Pathogenic	0.956
SLC26A4	O43511-1.1	V509D	Pathogenic	0.983
SLC26A4	O43511-1.1	V509E	Pathogenic	0.979
SLC26A4	O43511-1.1	V509F	Pathogenic	0.922
SLC26A4	O43511-1.1	V509G	Pathogenic	0.916
SLC26A4	O43511-1.1	V509H	Pathogenic	0.988
SLC26A4	O43511-1.1	V509I	Pathogenic	0.541
SLC26A4	O43511-1.1	V509K	Pathogenic	0.926
SLC26A4	O43511-1.1	V509L	Pathogenic	0.832
SLC26A4	O43511-1.1	V509M	Pathogenic	0.856
SLC26A4	O43511-1.1	V509N	Pathogenic	0.987
SLC26A4	O43511-1.1	V509P	Pathogenic	0.98
SLC26A4	O43511-1.1	V509Q	Pathogenic	0.978
SLC26A4	O43511-1.1	V509R	Pathogenic	0.933
SLC26A4	O43511-1.1	V509S	Pathogenic	0.943
SLC26A4	O43511-1.1	V509T	Pathogenic	0.919
SLC26A4	O43511-1.1	V509W	Pathogenic	0.918
SLC26A4	O43511-1.1	V509Y	Pathogenic	0.91
SLC26A4	O43511-1.1	V510A	Pathogenic	0.88
SLC26A4	O43511-1.1	V510C	Pathogenic	0.978
SLC26A4	O43511-1.1	V510D	Pathogenic	0.991
SLC26A4	O43511-1.1	V510E	Pathogenic	0.99
SLC26A4	O43511-1.1	V510F	Pathogenic	0.96
SLC26A4	O43511-1.1	V510G	Pathogenic	0.957
SLC26A4	O43511-1.1	V510H	Pathogenic	0.994
SLC26A4	O43511-1.1	V510I	Pathogenic	0.708
SLC26A4	O43511-1.1	V510K	Pathogenic	0.963
SLC26A4	O43511-1.1	V510L	Pathogenic	0.911
SLC26A4	O43511-1.1	V510M	Pathogenic	0.924
SLC26A4	O43511-1.1	V510N	Pathogenic	0.994
SLC26A4	O43511-1.1	V510P	Pathogenic	0.99
SLC26A4	O43511-1.1	V510Q	Pathogenic	0.989
SLC26A4	O43511-1.1	V510R	Pathogenic	0.966
SLC26A4	O43511-1.1	V510S	Pathogenic	0.972
SLC26A4	O43511-1.1	V510T	Pathogenic	0.959
SLC26A4	O43511-1.1	V510W	Pathogenic	0.958
SLC26A4	O43511-1.1	V510Y	Pathogenic	0.954
SLC26A4	O43511-1.1	L511A	Neutral	0.094
SLC26A4	O43511-1.1	L511C	Neutral	0.242
SLC26A4	O43511-1.1	L511D	Pathogenic	0.622
SLC26A4	O43511-1.1	L511E	Pathogenic	0.66
SLC26A4	O43511-1.1	L511F	Neutral	0.406
SLC26A4	O43511-1.1	L511G	Neutral	0.241
SLC26A4	O43511-1.1	L511H	Pathogenic	0.797
SLC26A4	O43511-1.1	L511I	Neutral	0.217
SLC26A4	O43511-1.1	L511K	Pathogenic	0.503
SLC26A4	O43511-1.1	L511M	Neutral	0.194
SLC26A4	O43511-1.1	L511N	Pathogenic	0.523
SLC26A4	O43511-1.1	L511P	Pathogenic	0.582
SLC26A4	O43511-1.1	L511Q	Pathogenic	0.588
SLC26A4	O43511-1.1	L511R	Neutral	0.359
SLC26A4	O43511-1.1	L511S	Neutral	0.194
SLC26A4	O43511-1.1	L511T	Neutral	0.248
SLC26A4	O43511-1.1	L511V	Neutral	0.169
SLC26A4	O43511-1.1	L511W	Neutral	0.395
SLC26A4	O43511-1.1	L511Y	Neutral	0.449
SLC26A4	O43511-1.1	R512A	Pathogenic	0.977
SLC26A4	O43511-1.1	R512C	Pathogenic	0.997
SLC26A4	O43511-1.1	R512D	Pathogenic	0.997
SLC26A4	O43511-1.1	R512E	Pathogenic	0.995
SLC26A4	O43511-1.1	R512F	Pathogenic	1.0
SLC26A4	O43511-1.1	R512G	Pathogenic	0.976
SLC26A4	O43511-1.1	R512H	Pathogenic	0.996
SLC26A4	O43511-1.1	R512I	Pathogenic	0.999
SLC26A4	O43511-1.1	R512K	Pathogenic	0.995
SLC26A4	O43511-1.1	R512L	Pathogenic	0.998
SLC26A4	O43511-1.1	R512M	Pathogenic	0.997
SLC26A4	O43511-1.1	R512N	Pathogenic	0.991
SLC26A4	O43511-1.1	R512P	Pathogenic	0.995
SLC26A4	O43511-1.1	R512Q	Pathogenic	0.991
SLC26A4	O43511-1.1	R512S	Pathogenic	0.984
SLC26A4	O43511-1.1	R512T	Pathogenic	0.993
SLC26A4	O43511-1.1	R512V	Pathogenic	0.999
SLC26A4	O43511-1.1	R512W	Pathogenic	0.999
SLC26A4	O43511-1.1	R512Y	Pathogenic	0.999
SLC26A4	O43511-1.1	V513A	Neutral	0.163
SLC26A4	O43511-1.1	V513C	Pathogenic	0.545
SLC26A4	O43511-1.1	V513D	Pathogenic	0.755
SLC26A4	O43511-1.1	V513E	Pathogenic	0.717
SLC26A4	O43511-1.1	V513F	Neutral	0.39
SLC26A4	O43511-1.1	V513G	Neutral	0.373
SLC26A4	O43511-1.1	V513H	Pathogenic	0.82
SLC26A4	O43511-1.1	V513I	Neutral	0.06
SLC26A4	O43511-1.1	V513K	Neutral	0.407
SLC26A4	O43511-1.1	V513L	Neutral	0.212
SLC26A4	O43511-1.1	V513M	Neutral	0.244
SLC26A4	O43511-1.1	V513N	Pathogenic	0.805
SLC26A4	O43511-1.1	V513P	Pathogenic	0.723
SLC26A4	O43511-1.1	V513Q	Pathogenic	0.704
SLC26A4	O43511-1.1	V513R	Neutral	0.432
SLC26A4	O43511-1.1	V513S	Neutral	0.475
SLC26A4	O43511-1.1	V513T	Neutral	0.382
SLC26A4	O43511-1.1	V513W	Neutral	0.379
SLC26A4	O43511-1.1	V513Y	Neutral	0.356
SLC26A4	O43511-1.1	Q514A	Pathogenic	0.997
SLC26A4	O43511-1.1	Q514C	Pathogenic	1.0
SLC26A4	O43511-1.1	Q514D	Pathogenic	0.998
SLC26A4	O43511-1.1	Q514E	Pathogenic	0.996
SLC26A4	O43511-1.1	Q514F	Pathogenic	1.0
SLC26A4	O43511-1.1	Q514G	Pathogenic	0.997
SLC26A4	O43511-1.1	Q514H	Pathogenic	0.999
SLC26A4	O43511-1.1	Q514I	Pathogenic	1.0
SLC26A4	O43511-1.1	Q514K	Pathogenic	0.996
SLC26A4	O43511-1.1	Q514L	Pathogenic	1.0
SLC26A4	O43511-1.1	Q514M	Pathogenic	0.998
SLC26A4	O43511-1.1	Q514N	Pathogenic	0.998
SLC26A4	O43511-1.1	Q514P	Pathogenic	0.999
SLC26A4	O43511-1.1	Q514R	Pathogenic	0.992
SLC26A4	O43511-1.1	Q514S	Pathogenic	0.996
SLC26A4	O43511-1.1	Q514T	Pathogenic	0.999
SLC26A4	O43511-1.1	Q514V	Pathogenic	1.0
SLC26A4	O43511-1.1	Q514W	Pathogenic	0.996
SLC26A4	O43511-1.1	Q514Y	Pathogenic	0.998
SLC26A4	O43511-1.1	F515A	Pathogenic	0.833
SLC26A4	O43511-1.1	F515C	Pathogenic	0.938
SLC26A4	O43511-1.1	F515D	Pathogenic	0.951
SLC26A4	O43511-1.1	F515E	Pathogenic	0.979
SLC26A4	O43511-1.1	F515G	Pathogenic	0.79
SLC26A4	O43511-1.1	F515H	Pathogenic	0.959
SLC26A4	O43511-1.1	F515I	Pathogenic	0.966
SLC26A4	O43511-1.1	F515K	Pathogenic	0.992
SLC26A4	O43511-1.1	F515L	Pathogenic	0.965
SLC26A4	O43511-1.1	F515M	Pathogenic	0.958
SLC26A4	O43511-1.1	F515N	Pathogenic	0.963
SLC26A4	O43511-1.1	F515P	Pathogenic	0.985
SLC26A4	O43511-1.1	F515Q	Pathogenic	0.986
SLC26A4	O43511-1.1	F515R	Pathogenic	0.986
SLC26A4	O43511-1.1	F515S	Pathogenic	0.851
SLC26A4	O43511-1.1	F515T	Pathogenic	0.94
SLC26A4	O43511-1.1	F515V	Pathogenic	0.951
SLC26A4	O43511-1.1	F515W	Pathogenic	0.847
SLC26A4	O43511-1.1	F515Y	Pathogenic	0.762
SLC26A4	O43511-1.1	P516A	Pathogenic	0.998
SLC26A4	O43511-1.1	P516C	Pathogenic	1.0
SLC26A4	O43511-1.1	P516D	Pathogenic	0.999
SLC26A4	O43511-1.1	P516E	Pathogenic	0.998
SLC26A4	O43511-1.1	P516F	Pathogenic	0.999
SLC26A4	O43511-1.1	P516G	Pathogenic	0.998
SLC26A4	O43511-1.1	P516H	Pathogenic	0.999
SLC26A4	O43511-1.1	P516I	Pathogenic	0.999
SLC26A4	O43511-1.1	P516K	Pathogenic	0.993
SLC26A4	O43511-1.1	P516L	Pathogenic	0.999
SLC26A4	O43511-1.1	P516M	Pathogenic	0.999
SLC26A4	O43511-1.1	P516N	Pathogenic	0.999
SLC26A4	O43511-1.1	P516Q	Pathogenic	0.998
SLC26A4	O43511-1.1	P516R	Pathogenic	0.994
SLC26A4	O43511-1.1	P516S	Pathogenic	0.999
SLC26A4	O43511-1.1	P516T	Pathogenic	0.999
SLC26A4	O43511-1.1	P516V	Pathogenic	0.999
SLC26A4	O43511-1.1	P516W	Pathogenic	0.997
SLC26A4	O43511-1.1	P516Y	Pathogenic	0.999
SLC26A4	O43511-1.1	S517A	Pathogenic	0.629
SLC26A4	O43511-1.1	S517C	Pathogenic	0.794
SLC26A4	O43511-1.1	S517D	Pathogenic	0.631
SLC26A4	O43511-1.1	S517E	Neutral	0.443
SLC26A4	O43511-1.1	S517F	Neutral	0.383
SLC26A4	O43511-1.1	S517G	Pathogenic	0.619
SLC26A4	O43511-1.1	S517H	Pathogenic	0.557
SLC26A4	O43511-1.1	S517I	Pathogenic	0.503
SLC26A4	O43511-1.1	S517K	Neutral	0.177
SLC26A4	O43511-1.1	S517L	Pathogenic	0.513
SLC26A4	O43511-1.1	S517M	Neutral	0.386
SLC26A4	O43511-1.1	S517N	Neutral	0.42
SLC26A4	O43511-1.1	S517P	Pathogenic	0.781
SLC26A4	O43511-1.1	S517Q	Neutral	0.428
SLC26A4	O43511-1.1	S517R	Neutral	0.193
SLC26A4	O43511-1.1	S517T	Neutral	0.479
SLC26A4	O43511-1.1	S517V	Pathogenic	0.75
SLC26A4	O43511-1.1	S517W	Neutral	0.228
SLC26A4	O43511-1.1	S517Y	Neutral	0.394
SLC26A4	O43511-1.1	W518A	Pathogenic	0.946
SLC26A4	O43511-1.1	W518C	Pathogenic	0.964
SLC26A4	O43511-1.1	W518D	Pathogenic	0.986
SLC26A4	O43511-1.1	W518E	Pathogenic	0.988
SLC26A4	O43511-1.1	W518F	Pathogenic	0.976
SLC26A4	O43511-1.1	W518G	Pathogenic	0.767
SLC26A4	O43511-1.1	W518H	Pathogenic	0.988
SLC26A4	O43511-1.1	W518I	Pathogenic	0.998
SLC26A4	O43511-1.1	W518K	Pathogenic	0.996
SLC26A4	O43511-1.1	W518L	Pathogenic	0.995
SLC26A4	O43511-1.1	W518M	Pathogenic	0.988
SLC26A4	O43511-1.1	W518N	Pathogenic	0.989
SLC26A4	O43511-1.1	W518P	Pathogenic	0.991
SLC26A4	O43511-1.1	W518Q	Pathogenic	0.983
SLC26A4	O43511-1.1	W518R	Pathogenic	0.998
SLC26A4	O43511-1.1	W518S	Pathogenic	0.953
SLC26A4	O43511-1.1	W518T	Pathogenic	0.965
SLC26A4	O43511-1.1	W518V	Pathogenic	0.993
SLC26A4	O43511-1.1	W518Y	Pathogenic	0.951
SLC26A4	O43511-1.1	N519A	Pathogenic	0.501
SLC26A4	O43511-1.1	N519C	Pathogenic	0.786
SLC26A4	O43511-1.1	N519D	Neutral	0.327
SLC26A4	O43511-1.1	N519E	Neutral	0.417
SLC26A4	O43511-1.1	N519F	Neutral	0.42
SLC26A4	O43511-1.1	N519G	Neutral	0.106
SLC26A4	O43511-1.1	N519H	Neutral	0.154
SLC26A4	O43511-1.1	N519I	Pathogenic	0.542
SLC26A4	O43511-1.1	N519K	Neutral	0.162
SLC26A4	O43511-1.1	N519L	Pathogenic	0.552
SLC26A4	O43511-1.1	N519M	Neutral	0.424
SLC26A4	O43511-1.1	N519P	Pathogenic	0.708
SLC26A4	O43511-1.1	N519Q	Neutral	0.334
SLC26A4	O43511-1.1	N519R	Neutral	0.097
SLC26A4	O43511-1.1	N519S	Neutral	0.156
SLC26A4	O43511-1.1	N519T	Neutral	0.451
SLC26A4	O43511-1.1	N519V	Pathogenic	0.778
SLC26A4	O43511-1.1	N519W	Neutral	0.256
SLC26A4	O43511-1.1	N519Y	Neutral	0.275
SLC26A4	O43511-1.1	G520A	Neutral	0.057
SLC26A4	O43511-1.1	G520C	Neutral	0.137
SLC26A4	O43511-1.1	G520D	Neutral	0.033
SLC26A4	O43511-1.1	G520E	Neutral	0.031
SLC26A4	O43511-1.1	G520F	Neutral	0.013
SLC26A4	O43511-1.1	G520H	Neutral	0.025
SLC26A4	O43511-1.1	G520I	Neutral	0.04
SLC26A4	O43511-1.1	G520K	Neutral	0.009
SLC26A4	O43511-1.1	G520L	Neutral	0.042
SLC26A4	O43511-1.1	G520M	Neutral	0.025
SLC26A4	O43511-1.1	G520N	Neutral	0.014
SLC26A4	O43511-1.1	G520P	Neutral	0.068
SLC26A4	O43511-1.1	G520Q	Neutral	0.029
SLC26A4	O43511-1.1	G520R	Neutral	0.005
SLC26A4	O43511-1.1	G520S	Neutral	0.048
SLC26A4	O43511-1.1	G520T	Neutral	0.071
SLC26A4	O43511-1.1	G520V	Neutral	0.058
SLC26A4	O43511-1.1	G520W	Neutral	0.002
SLC26A4	O43511-1.1	G520Y	Neutral	0.013
SLC26A4	O43511-1.1	L521A	Pathogenic	0.842
SLC26A4	O43511-1.1	L521C	Pathogenic	0.942
SLC26A4	O43511-1.1	L521D	Pathogenic	0.988
SLC26A4	O43511-1.1	L521E	Pathogenic	0.99
SLC26A4	O43511-1.1	L521F	Pathogenic	0.972
SLC26A4	O43511-1.1	L521G	Pathogenic	0.942
SLC26A4	O43511-1.1	L521H	Pathogenic	0.995
SLC26A4	O43511-1.1	L521I	Pathogenic	0.934
SLC26A4	O43511-1.1	L521K	Pathogenic	0.981
SLC26A4	O43511-1.1	L521M	Pathogenic	0.925
SLC26A4	O43511-1.1	L521N	Pathogenic	0.983
SLC26A4	O43511-1.1	L521P	Pathogenic	0.986
SLC26A4	O43511-1.1	L521Q	Pathogenic	0.987
SLC26A4	O43511-1.1	L521R	Pathogenic	0.966
SLC26A4	O43511-1.1	L521S	Pathogenic	0.925
SLC26A4	O43511-1.1	L521T	Pathogenic	0.944
SLC26A4	O43511-1.1	L521V	Pathogenic	0.913
SLC26A4	O43511-1.1	L521W	Pathogenic	0.971
SLC26A4	O43511-1.1	L521Y	Pathogenic	0.977
SLC26A4	O43511-1.1	G522A	Pathogenic	0.87
SLC26A4	O43511-1.1	G522C	Pathogenic	0.947
SLC26A4	O43511-1.1	G522D	Pathogenic	0.792
SLC26A4	O43511-1.1	G522E	Pathogenic	0.781
SLC26A4	O43511-1.1	G522F	Pathogenic	0.588
SLC26A4	O43511-1.1	G522H	Pathogenic	0.743
SLC26A4	O43511-1.1	G522I	Pathogenic	0.824
SLC26A4	O43511-1.1	G522K	Neutral	0.491
SLC26A4	O43511-1.1	G522L	Pathogenic	0.83
SLC26A4	O43511-1.1	G522M	Pathogenic	0.744
SLC26A4	O43511-1.1	G522N	Pathogenic	0.618
SLC26A4	O43511-1.1	G522P	Pathogenic	0.891
SLC26A4	O43511-1.1	G522Q	Pathogenic	0.77
SLC26A4	O43511-1.1	G522R	Neutral	0.348
SLC26A4	O43511-1.1	G522S	Pathogenic	0.85
SLC26A4	O43511-1.1	G522T	Pathogenic	0.895
SLC26A4	O43511-1.1	G522V	Pathogenic	0.873
SLC26A4	O43511-1.1	G522W	Neutral	0.144
SLC26A4	O43511-1.1	G522Y	Pathogenic	0.599
SLC26A4	O43511-1.1	S523A	Neutral	0.456
SLC26A4	O43511-1.1	S523C	Pathogenic	0.655
SLC26A4	O43511-1.1	S523D	Neutral	0.457
SLC26A4	O43511-1.1	S523E	Neutral	0.282
SLC26A4	O43511-1.1	S523F	Neutral	0.235
SLC26A4	O43511-1.1	S523G	Neutral	0.446
SLC26A4	O43511-1.1	S523H	Neutral	0.384
SLC26A4	O43511-1.1	S523I	Neutral	0.334
SLC26A4	O43511-1.1	S523K	Neutral	0.096
SLC26A4	O43511-1.1	S523L	Neutral	0.343
SLC26A4	O43511-1.1	S523M	Neutral	0.237
SLC26A4	O43511-1.1	S523N	Neutral	0.263
SLC26A4	O43511-1.1	S523P	Pathogenic	0.637
SLC26A4	O43511-1.1	S523Q	Neutral	0.27
SLC26A4	O43511-1.1	S523R	Neutral	0.106
SLC26A4	O43511-1.1	S523T	Neutral	0.312
SLC26A4	O43511-1.1	S523V	Pathogenic	0.597
SLC26A4	O43511-1.1	S523W	Neutral	0.127
SLC26A4	O43511-1.1	S523Y	Neutral	0.243
SLC26A4	O43511-1.1	I524A	Pathogenic	0.506
SLC26A4	O43511-1.1	I524C	Pathogenic	0.758
SLC26A4	O43511-1.1	I524D	Pathogenic	0.89
SLC26A4	O43511-1.1	I524E	Pathogenic	0.95
SLC26A4	O43511-1.1	I524F	Pathogenic	0.878
SLC26A4	O43511-1.1	I524G	Pathogenic	0.758
SLC26A4	O43511-1.1	I524H	Pathogenic	0.975
SLC26A4	O43511-1.1	I524K	Pathogenic	0.952
SLC26A4	O43511-1.1	I524L	Pathogenic	0.739
SLC26A4	O43511-1.1	I524M	Pathogenic	0.826
SLC26A4	O43511-1.1	I524N	Pathogenic	0.915
SLC26A4	O43511-1.1	I524P	Pathogenic	0.932
SLC26A4	O43511-1.1	I524Q	Pathogenic	0.966
SLC26A4	O43511-1.1	I524R	Pathogenic	0.917
SLC26A4	O43511-1.1	I524S	Pathogenic	0.703
SLC26A4	O43511-1.1	I524T	Pathogenic	0.765
SLC26A4	O43511-1.1	I524V	Neutral	0.332
SLC26A4	O43511-1.1	I524W	Pathogenic	0.933
SLC26A4	O43511-1.1	I524Y	Pathogenic	0.889
SLC26A4	O43511-1.1	P525A	Pathogenic	0.91
SLC26A4	O43511-1.1	P525C	Pathogenic	0.99
SLC26A4	O43511-1.1	P525D	Pathogenic	0.947
SLC26A4	O43511-1.1	P525E	Pathogenic	0.893
SLC26A4	O43511-1.1	P525F	Pathogenic	0.959
SLC26A4	O43511-1.1	P525G	Pathogenic	0.884
SLC26A4	O43511-1.1	P525H	Pathogenic	0.938
SLC26A4	O43511-1.1	P525I	Pathogenic	0.95
SLC26A4	O43511-1.1	P525K	Pathogenic	0.693
SLC26A4	O43511-1.1	P525L	Pathogenic	0.952
SLC26A4	O43511-1.1	P525M	Pathogenic	0.922
SLC26A4	O43511-1.1	P525N	Pathogenic	0.968
SLC26A4	O43511-1.1	P525Q	Pathogenic	0.887
SLC26A4	O43511-1.1	P525R	Pathogenic	0.715
SLC26A4	O43511-1.1	P525S	Pathogenic	0.92
SLC26A4	O43511-1.1	P525T	Pathogenic	0.96
SLC26A4	O43511-1.1	P525V	Pathogenic	0.966
SLC26A4	O43511-1.1	P525W	Pathogenic	0.847
SLC26A4	O43511-1.1	P525Y	Pathogenic	0.924
SLC26A4	O43511-1.1	S526A	Neutral	0.121
SLC26A4	O43511-1.1	S526C	Neutral	0.238
SLC26A4	O43511-1.1	S526D	Neutral	0.122
SLC26A4	O43511-1.1	S526E	Neutral	0.061
SLC26A4	O43511-1.1	S526F	Neutral	0.048
SLC26A4	O43511-1.1	S526G	Neutral	0.117
SLC26A4	O43511-1.1	S526H	Neutral	0.093
SLC26A4	O43511-1.1	S526I	Neutral	0.076
SLC26A4	O43511-1.1	S526K	Neutral	0.017
SLC26A4	O43511-1.1	S526L	Neutral	0.079
SLC26A4	O43511-1.1	S526M	Neutral	0.049
SLC26A4	O43511-1.1	S526N	Neutral	0.055
SLC26A4	O43511-1.1	S526P	Neutral	0.224
SLC26A4	O43511-1.1	S526Q	Neutral	0.057
SLC26A4	O43511-1.1	S526R	Neutral	0.019
SLC26A4	O43511-1.1	S526T	Neutral	0.069
SLC26A4	O43511-1.1	S526V	Neutral	0.196
SLC26A4	O43511-1.1	S526W	Neutral	0.023
SLC26A4	O43511-1.1	S526Y	Neutral	0.05
SLC26A4	O43511-1.1	T527A	Pathogenic	0.922
SLC26A4	O43511-1.1	T527C	Pathogenic	0.977
SLC26A4	O43511-1.1	T527D	Pathogenic	0.98
SLC26A4	O43511-1.1	T527E	Pathogenic	0.964
SLC26A4	O43511-1.1	T527F	Pathogenic	0.929
SLC26A4	O43511-1.1	T527G	Pathogenic	0.949
SLC26A4	O43511-1.1	T527H	Pathogenic	0.98
SLC26A4	O43511-1.1	T527I	Pathogenic	0.914
SLC26A4	O43511-1.1	T527K	Pathogenic	0.879
SLC26A4	O43511-1.1	T527L	Pathogenic	0.917
SLC26A4	O43511-1.1	T527M	Pathogenic	0.93
SLC26A4	O43511-1.1	T527N	Pathogenic	0.961
SLC26A4	O43511-1.1	T527P	Pathogenic	0.983
SLC26A4	O43511-1.1	T527Q	Pathogenic	0.962
SLC26A4	O43511-1.1	T527R	Pathogenic	0.801
SLC26A4	O43511-1.1	T527S	Pathogenic	0.875
SLC26A4	O43511-1.1	T527V	Pathogenic	0.94
SLC26A4	O43511-1.1	T527W	Pathogenic	0.756
SLC26A4	O43511-1.1	T527Y	Pathogenic	0.932
SLC26A4	O43511-1.1	D528A	Pathogenic	0.98
SLC26A4	O43511-1.1	D528C	Pathogenic	0.995
SLC26A4	O43511-1.1	D528E	Pathogenic	0.852
SLC26A4	O43511-1.1	D528F	Pathogenic	0.958
SLC26A4	O43511-1.1	D528G	Pathogenic	0.922
SLC26A4	O43511-1.1	D528H	Pathogenic	0.958
SLC26A4	O43511-1.1	D528I	Pathogenic	0.974
SLC26A4	O43511-1.1	D528K	Pathogenic	0.933
SLC26A4	O43511-1.1	D528L	Pathogenic	0.987
SLC26A4	O43511-1.1	D528M	Pathogenic	0.979
SLC26A4	O43511-1.1	D528N	Pathogenic	0.953
SLC26A4	O43511-1.1	D528P	Pathogenic	0.983
SLC26A4	O43511-1.1	D528Q	Pathogenic	0.94
SLC26A4	O43511-1.1	D528R	Pathogenic	0.939
SLC26A4	O43511-1.1	D528S	Pathogenic	0.948
SLC26A4	O43511-1.1	D528T	Pathogenic	0.985
SLC26A4	O43511-1.1	D528V	Pathogenic	0.991
SLC26A4	O43511-1.1	D528W	Pathogenic	0.916
SLC26A4	O43511-1.1	D528Y	Pathogenic	0.96
SLC26A4	O43511-1.1	I529A	Pathogenic	0.901
SLC26A4	O43511-1.1	I529C	Pathogenic	0.965
SLC26A4	O43511-1.1	I529D	Pathogenic	0.986
SLC26A4	O43511-1.1	I529E	Pathogenic	0.994
SLC26A4	O43511-1.1	I529F	Pathogenic	0.985
SLC26A4	O43511-1.1	I529G	Pathogenic	0.965
SLC26A4	O43511-1.1	I529H	Pathogenic	0.997
SLC26A4	O43511-1.1	I529K	Pathogenic	0.994
SLC26A4	O43511-1.1	I529L	Pathogenic	0.962
SLC26A4	O43511-1.1	I529M	Pathogenic	0.977
SLC26A4	O43511-1.1	I529N	Pathogenic	0.99
SLC26A4	O43511-1.1	I529P	Pathogenic	0.992
SLC26A4	O43511-1.1	I529Q	Pathogenic	0.996
SLC26A4	O43511-1.1	I529R	Pathogenic	0.99
SLC26A4	O43511-1.1	I529S	Pathogenic	0.955
SLC26A4	O43511-1.1	I529T	Pathogenic	0.966
SLC26A4	O43511-1.1	I529V	Pathogenic	0.815
SLC26A4	O43511-1.1	I529W	Pathogenic	0.992
SLC26A4	O43511-1.1	I529Y	Pathogenic	0.986
SLC26A4	O43511-1.1	Y530A	Pathogenic	0.996
SLC26A4	O43511-1.1	Y530C	Pathogenic	0.999
SLC26A4	O43511-1.1	Y530D	Pathogenic	0.999
SLC26A4	O43511-1.1	Y530E	Pathogenic	0.999
SLC26A4	O43511-1.1	Y530F	Pathogenic	0.994
SLC26A4	O43511-1.1	Y530G	Pathogenic	0.995
SLC26A4	O43511-1.1	Y530H	Pathogenic	0.993
SLC26A4	O43511-1.1	Y530I	Pathogenic	0.999
SLC26A4	O43511-1.1	Y530K	Pathogenic	1.0
SLC26A4	O43511-1.1	Y530L	Pathogenic	0.999
SLC26A4	O43511-1.1	Y530M	Pathogenic	0.999
SLC26A4	O43511-1.1	Y530N	Pathogenic	0.999
SLC26A4	O43511-1.1	Y530P	Pathogenic	0.999
SLC26A4	O43511-1.1	Y530Q	Pathogenic	0.999
SLC26A4	O43511-1.1	Y530R	Pathogenic	1.0
SLC26A4	O43511-1.1	Y530S	Pathogenic	0.997
SLC26A4	O43511-1.1	Y530T	Pathogenic	0.999
SLC26A4	O43511-1.1	Y530V	Pathogenic	0.999
SLC26A4	O43511-1.1	Y530W	Pathogenic	0.992
SLC26A4	O43511-1.1	K531A	Pathogenic	0.668
SLC26A4	O43511-1.1	K531C	Pathogenic	0.936
SLC26A4	O43511-1.1	K531D	Pathogenic	0.9
SLC26A4	O43511-1.1	K531E	Pathogenic	0.827
SLC26A4	O43511-1.1	K531F	Pathogenic	0.99
SLC26A4	O43511-1.1	K531G	Pathogenic	0.658
SLC26A4	O43511-1.1	K531H	Pathogenic	0.956
SLC26A4	O43511-1.1	K531I	Pathogenic	0.984
SLC26A4	O43511-1.1	K531L	Pathogenic	0.969
SLC26A4	O43511-1.1	K531M	Pathogenic	0.949
SLC26A4	O43511-1.1	K531N	Pathogenic	0.84
SLC26A4	O43511-1.1	K531P	Pathogenic	0.829
SLC26A4	O43511-1.1	K531Q	Pathogenic	0.836
SLC26A4	O43511-1.1	K531R	Pathogenic	0.829
SLC26A4	O43511-1.1	K531S	Pathogenic	0.599
SLC26A4	O43511-1.1	K531T	Pathogenic	0.869
SLC26A4	O43511-1.1	K531V	Pathogenic	0.94
SLC26A4	O43511-1.1	K531W	Pathogenic	0.959
SLC26A4	O43511-1.1	K531Y	Pathogenic	0.981
SLC26A4	O43511-1.1	S532A	Neutral	0.28
SLC26A4	O43511-1.1	S532C	Neutral	0.468
SLC26A4	O43511-1.1	S532D	Neutral	0.281
SLC26A4	O43511-1.1	S532E	Neutral	0.154
SLC26A4	O43511-1.1	S532F	Neutral	0.124
SLC26A4	O43511-1.1	S532G	Neutral	0.271
SLC26A4	O43511-1.1	S532H	Neutral	0.224
SLC26A4	O43511-1.1	S532I	Neutral	0.188
SLC26A4	O43511-1.1	S532K	Neutral	0.047
SLC26A4	O43511-1.1	S532L	Neutral	0.194
SLC26A4	O43511-1.1	S532M	Neutral	0.126
SLC26A4	O43511-1.1	S532N	Neutral	0.142
SLC26A4	O43511-1.1	S532P	Neutral	0.449
SLC26A4	O43511-1.1	S532Q	Neutral	0.146
SLC26A4	O43511-1.1	S532R	Neutral	0.052
SLC26A4	O43511-1.1	S532T	Neutral	0.174
SLC26A4	O43511-1.1	S532V	Neutral	0.407
SLC26A4	O43511-1.1	S532W	Neutral	0.063
SLC26A4	O43511-1.1	S532Y	Neutral	0.13
SLC26A4	O43511-1.1	T533A	Neutral	0.171
SLC26A4	O43511-1.1	T533C	Neutral	0.429
SLC26A4	O43511-1.1	T533D	Neutral	0.456
SLC26A4	O43511-1.1	T533E	Neutral	0.319
SLC26A4	O43511-1.1	T533F	Neutral	0.186
SLC26A4	O43511-1.1	T533G	Neutral	0.245
SLC26A4	O43511-1.1	T533H	Neutral	0.458
SLC26A4	O43511-1.1	T533I	Neutral	0.156
SLC26A4	O43511-1.1	T533K	Neutral	0.112
SLC26A4	O43511-1.1	T533L	Neutral	0.162
SLC26A4	O43511-1.1	T533M	Neutral	0.188
SLC26A4	O43511-1.1	T533N	Neutral	0.299
SLC26A4	O43511-1.1	T533P	Neutral	0.499
SLC26A4	O43511-1.1	T533Q	Neutral	0.305
SLC26A4	O43511-1.1	T533R	Neutral	0.065
SLC26A4	O43511-1.1	T533S	Neutral	0.109
SLC26A4	O43511-1.1	T533V	Neutral	0.214
SLC26A4	O43511-1.1	T533W	Neutral	0.051
SLC26A4	O43511-1.1	T533Y	Neutral	0.193
SLC26A4	O43511-1.1	K534A	Pathogenic	0.893
SLC26A4	O43511-1.1	K534C	Pathogenic	0.984
SLC26A4	O43511-1.1	K534D	Pathogenic	0.974
SLC26A4	O43511-1.1	K534E	Pathogenic	0.952
SLC26A4	O43511-1.1	K534F	Pathogenic	0.998
SLC26A4	O43511-1.1	K534G	Pathogenic	0.889
SLC26A4	O43511-1.1	K534H	Pathogenic	0.989
SLC26A4	O43511-1.1	K534I	Pathogenic	0.996
SLC26A4	O43511-1.1	K534L	Pathogenic	0.992
SLC26A4	O43511-1.1	K534M	Pathogenic	0.987
SLC26A4	O43511-1.1	K534N	Pathogenic	0.956
SLC26A4	O43511-1.1	K534P	Pathogenic	0.953
SLC26A4	O43511-1.1	K534Q	Pathogenic	0.955
SLC26A4	O43511-1.1	K534R	Pathogenic	0.953
SLC26A4	O43511-1.1	K534S	Pathogenic	0.862
SLC26A4	O43511-1.1	K534T	Pathogenic	0.965
SLC26A4	O43511-1.1	K534V	Pathogenic	0.985
SLC26A4	O43511-1.1	K534W	Pathogenic	0.99
SLC26A4	O43511-1.1	K534Y	Pathogenic	0.995
SLC26A4	O43511-1.1	N535A	Pathogenic	0.602
SLC26A4	O43511-1.1	N535C	Pathogenic	0.847
SLC26A4	O43511-1.1	N535D	Neutral	0.423
SLC26A4	O43511-1.1	N535E	Pathogenic	0.52
SLC26A4	O43511-1.1	N535F	Pathogenic	0.523
SLC26A4	O43511-1.1	N535G	Neutral	0.152
SLC26A4	O43511-1.1	N535H	Neutral	0.215
SLC26A4	O43511-1.1	N535I	Pathogenic	0.641
SLC26A4	O43511-1.1	N535K	Neutral	0.226
SLC26A4	O43511-1.1	N535L	Pathogenic	0.65
SLC26A4	O43511-1.1	N535M	Pathogenic	0.526
SLC26A4	O43511-1.1	N535P	Pathogenic	0.785
SLC26A4	O43511-1.1	N535Q	Neutral	0.43
SLC26A4	O43511-1.1	N535R	Neutral	0.139
SLC26A4	O43511-1.1	N535S	Neutral	0.219
SLC26A4	O43511-1.1	N535T	Pathogenic	0.553
SLC26A4	O43511-1.1	N535V	Pathogenic	0.841
SLC26A4	O43511-1.1	N535W	Neutral	0.342
SLC26A4	O43511-1.1	N535Y	Neutral	0.364
SLC26A4	O43511-1.1	Y536A	Pathogenic	0.996
SLC26A4	O43511-1.1	Y536C	Pathogenic	0.999
SLC26A4	O43511-1.1	Y536D	Pathogenic	0.999
SLC26A4	O43511-1.1	Y536E	Pathogenic	0.999
SLC26A4	O43511-1.1	Y536F	Pathogenic	0.993
SLC26A4	O43511-1.1	Y536G	Pathogenic	0.994
SLC26A4	O43511-1.1	Y536H	Pathogenic	0.993
SLC26A4	O43511-1.1	Y536I	Pathogenic	0.999
SLC26A4	O43511-1.1	Y536K	Pathogenic	1.0
SLC26A4	O43511-1.1	Y536L	Pathogenic	0.999
SLC26A4	O43511-1.1	Y536M	Pathogenic	0.999
SLC26A4	O43511-1.1	Y536N	Pathogenic	0.998
SLC26A4	O43511-1.1	Y536P	Pathogenic	0.999
SLC26A4	O43511-1.1	Y536Q	Pathogenic	0.999
SLC26A4	O43511-1.1	Y536R	Pathogenic	1.0
SLC26A4	O43511-1.1	Y536S	Pathogenic	0.996
SLC26A4	O43511-1.1	Y536T	Pathogenic	0.999
SLC26A4	O43511-1.1	Y536V	Pathogenic	0.999
SLC26A4	O43511-1.1	Y536W	Pathogenic	0.992
SLC26A4	O43511-1.1	K537A	Neutral	0.053
SLC26A4	O43511-1.1	K537C	Neutral	0.291
SLC26A4	O43511-1.1	K537D	Neutral	0.2
SLC26A4	O43511-1.1	K537E	Neutral	0.117
SLC26A4	O43511-1.1	K537F	Pathogenic	0.733
SLC26A4	O43511-1.1	K537G	Neutral	0.051
SLC26A4	O43511-1.1	K537H	Neutral	0.374
SLC26A4	O43511-1.1	K537I	Pathogenic	0.624
SLC26A4	O43511-1.1	K537L	Neutral	0.463
SLC26A4	O43511-1.1	K537M	Neutral	0.339
SLC26A4	O43511-1.1	K537N	Neutral	0.128
SLC26A4	O43511-1.1	K537P	Neutral	0.119
SLC26A4	O43511-1.1	K537Q	Neutral	0.124
SLC26A4	O43511-1.1	K537R	Neutral	0.119
SLC26A4	O43511-1.1	K537S	Neutral	0.04
SLC26A4	O43511-1.1	K537T	Neutral	0.156
SLC26A4	O43511-1.1	K537V	Neutral	0.306
SLC26A4	O43511-1.1	K537W	Neutral	0.394
SLC26A4	O43511-1.1	K537Y	Pathogenic	0.589
SLC26A4	O43511-1.1	N538A	Pathogenic	0.879
SLC26A4	O43511-1.1	N538C	Pathogenic	0.964
SLC26A4	O43511-1.1	N538D	Pathogenic	0.778
SLC26A4	O43511-1.1	N538E	Pathogenic	0.838
SLC26A4	O43511-1.1	N538F	Pathogenic	0.839
SLC26A4	O43511-1.1	N538G	Neutral	0.461
SLC26A4	O43511-1.1	N538H	Pathogenic	0.567
SLC26A4	O43511-1.1	N538I	Pathogenic	0.895
SLC26A4	O43511-1.1	N538K	Pathogenic	0.582
SLC26A4	O43511-1.1	N538L	Pathogenic	0.899
SLC26A4	O43511-1.1	N538M	Pathogenic	0.841
SLC26A4	O43511-1.1	N538P	Pathogenic	0.946
SLC26A4	O43511-1.1	N538Q	Pathogenic	0.783
SLC26A4	O43511-1.1	N538R	Neutral	0.435
SLC26A4	O43511-1.1	N538S	Pathogenic	0.572
SLC26A4	O43511-1.1	N538T	Pathogenic	0.855
SLC26A4	O43511-1.1	N538V	Pathogenic	0.962
SLC26A4	O43511-1.1	N538W	Pathogenic	0.713
SLC26A4	O43511-1.1	N538Y	Pathogenic	0.732
SLC26A4	O43511-1.1	I539A	Neutral	0.198
SLC26A4	O43511-1.1	I539C	Neutral	0.429
SLC26A4	O43511-1.1	I539D	Pathogenic	0.66
SLC26A4	O43511-1.1	I539E	Pathogenic	0.821
SLC26A4	O43511-1.1	I539F	Pathogenic	0.634
SLC26A4	O43511-1.1	I539G	Neutral	0.429
SLC26A4	O43511-1.1	I539H	Pathogenic	0.903
SLC26A4	O43511-1.1	I539K	Pathogenic	0.828
SLC26A4	O43511-1.1	I539L	Neutral	0.405
SLC26A4	O43511-1.1	I539M	Pathogenic	0.533
SLC26A4	O43511-1.1	I539N	Pathogenic	0.722
SLC26A4	O43511-1.1	I539P	Pathogenic	0.767
SLC26A4	O43511-1.1	I539Q	Pathogenic	0.871
SLC26A4	O43511-1.1	I539R	Pathogenic	0.727
SLC26A4	O43511-1.1	I539S	Neutral	0.362
SLC26A4	O43511-1.1	I539T	Neutral	0.438
SLC26A4	O43511-1.1	I539V	Neutral	0.107
SLC26A4	O43511-1.1	I539W	Pathogenic	0.77
SLC26A4	O43511-1.1	I539Y	Pathogenic	0.658
SLC26A4	O43511-1.1	E540A	Neutral	0.17
SLC26A4	O43511-1.1	E540C	Pathogenic	0.751
SLC26A4	O43511-1.1	E540D	Neutral	0.093
SLC26A4	O43511-1.1	E540F	Neutral	0.49
SLC26A4	O43511-1.1	E540G	Neutral	0.164
SLC26A4	O43511-1.1	E540H	Neutral	0.326
SLC26A4	O43511-1.1	E540I	Pathogenic	0.611
SLC26A4	O43511-1.1	E540K	Neutral	0.116
SLC26A4	O43511-1.1	E540L	Pathogenic	0.62
SLC26A4	O43511-1.1	E540M	Neutral	0.494
SLC26A4	O43511-1.1	E540N	Neutral	0.349
SLC26A4	O43511-1.1	E540P	Neutral	0.331
SLC26A4	O43511-1.1	E540Q	Neutral	0.141
SLC26A4	O43511-1.1	E540R	Neutral	0.127
SLC26A4	O43511-1.1	E540S	Neutral	0.132
SLC26A4	O43511-1.1	E540T	Neutral	0.403
SLC26A4	O43511-1.1	E540V	Pathogenic	0.617
SLC26A4	O43511-1.1	E540W	Neutral	0.185
SLC26A4	O43511-1.1	E540Y	Neutral	0.334
SLC26A4	O43511-1.1	E541A	Pathogenic	0.99
SLC26A4	O43511-1.1	E541C	Pathogenic	0.999
SLC26A4	O43511-1.1	E541D	Pathogenic	0.98
SLC26A4	O43511-1.1	E541F	Pathogenic	0.998
SLC26A4	O43511-1.1	E541G	Pathogenic	0.99
SLC26A4	O43511-1.1	E541H	Pathogenic	0.996
SLC26A4	O43511-1.1	E541I	Pathogenic	0.999
SLC26A4	O43511-1.1	E541K	Pathogenic	0.985
SLC26A4	O43511-1.1	E541L	Pathogenic	0.999
SLC26A4	O43511-1.1	E541M	Pathogenic	0.998
SLC26A4	O43511-1.1	E541N	Pathogenic	0.996
SLC26A4	O43511-1.1	E541P	Pathogenic	0.996
SLC26A4	O43511-1.1	E541Q	Pathogenic	0.988
SLC26A4	O43511-1.1	E541R	Pathogenic	0.986
SLC26A4	O43511-1.1	E541S	Pathogenic	0.987
SLC26A4	O43511-1.1	E541T	Pathogenic	0.997
SLC26A4	O43511-1.1	E541V	Pathogenic	0.999
SLC26A4	O43511-1.1	E541W	Pathogenic	0.991
SLC26A4	O43511-1.1	E541Y	Pathogenic	0.996
SLC26A4	O43511-1.1	P542A	Pathogenic	0.97
SLC26A4	O43511-1.1	P542C	Pathogenic	0.997
SLC26A4	O43511-1.1	P542D	Pathogenic	0.983
SLC26A4	O43511-1.1	P542E	Pathogenic	0.964
SLC26A4	O43511-1.1	P542F	Pathogenic	0.987
SLC26A4	O43511-1.1	P542G	Pathogenic	0.96
SLC26A4	O43511-1.1	P542H	Pathogenic	0.979
SLC26A4	O43511-1.1	P542I	Pathogenic	0.984
SLC26A4	O43511-1.1	P542K	Pathogenic	0.877
SLC26A4	O43511-1.1	P542L	Pathogenic	0.984
SLC26A4	O43511-1.1	P542M	Pathogenic	0.974
SLC26A4	O43511-1.1	P542N	Pathogenic	0.99
SLC26A4	O43511-1.1	P542Q	Pathogenic	0.961
SLC26A4	O43511-1.1	P542R	Pathogenic	0.888
SLC26A4	O43511-1.1	P542S	Pathogenic	0.973
SLC26A4	O43511-1.1	P542T	Pathogenic	0.987
SLC26A4	O43511-1.1	P542V	Pathogenic	0.989
SLC26A4	O43511-1.1	P542W	Pathogenic	0.946
SLC26A4	O43511-1.1	P542Y	Pathogenic	0.975
SLC26A4	O43511-1.1	Q543A	Neutral	0.137
SLC26A4	O43511-1.1	Q543C	Pathogenic	0.537
SLC26A4	O43511-1.1	Q543D	Neutral	0.187
SLC26A4	O43511-1.1	Q543E	Neutral	0.119
SLC26A4	O43511-1.1	Q543F	Pathogenic	0.539
SLC26A4	O43511-1.1	Q543G	Neutral	0.132
SLC26A4	O43511-1.1	Q543H	Neutral	0.37
SLC26A4	O43511-1.1	Q543I	Pathogenic	0.656
SLC26A4	O43511-1.1	Q543K	Neutral	0.104
SLC26A4	O43511-1.1	Q543L	Neutral	0.497
SLC26A4	O43511-1.1	Q543M	Neutral	0.227
SLC26A4	O43511-1.1	Q543N	Neutral	0.236
SLC26A4	O43511-1.1	Q543P	Neutral	0.276
SLC26A4	O43511-1.1	Q543R	Neutral	0.06
SLC26A4	O43511-1.1	Q543S	Neutral	0.105
SLC26A4	O43511-1.1	Q543T	Neutral	0.343
SLC26A4	O43511-1.1	Q543V	Pathogenic	0.554
SLC26A4	O43511-1.1	Q543W	Neutral	0.121
SLC26A4	O43511-1.1	Q543Y	Neutral	0.233
SLC26A4	O43511-1.1	G544A	Pathogenic	0.994
SLC26A4	O43511-1.1	G544C	Pathogenic	0.998
SLC26A4	O43511-1.1	G544D	Pathogenic	0.99
SLC26A4	O43511-1.1	G544E	Pathogenic	0.989
SLC26A4	O43511-1.1	G544F	Pathogenic	0.974
SLC26A4	O43511-1.1	G544H	Pathogenic	0.987
SLC26A4	O43511-1.1	G544I	Pathogenic	0.992
SLC26A4	O43511-1.1	G544K	Pathogenic	0.962
SLC26A4	O43511-1.1	G544L	Pathogenic	0.992
SLC26A4	O43511-1.1	G544M	Pathogenic	0.987
SLC26A4	O43511-1.1	G544N	Pathogenic	0.977
SLC26A4	O43511-1.1	G544P	Pathogenic	0.995
SLC26A4	O43511-1.1	G544Q	Pathogenic	0.989
SLC26A4	O43511-1.1	G544R	Pathogenic	0.933
SLC26A4	O43511-1.1	G544S	Pathogenic	0.993
SLC26A4	O43511-1.1	G544T	Pathogenic	0.996
SLC26A4	O43511-1.1	G544V	Pathogenic	0.994
SLC26A4	O43511-1.1	G544W	Pathogenic	0.814
SLC26A4	O43511-1.1	G544Y	Pathogenic	0.975
SLC26A4	O43511-1.1	V545A	Pathogenic	0.829
SLC26A4	O43511-1.1	V545C	Pathogenic	0.967
SLC26A4	O43511-1.1	V545D	Pathogenic	0.987
SLC26A4	O43511-1.1	V545E	Pathogenic	0.984
SLC26A4	O43511-1.1	V545F	Pathogenic	0.941
SLC26A4	O43511-1.1	V545G	Pathogenic	0.937
SLC26A4	O43511-1.1	V545H	Pathogenic	0.991
SLC26A4	O43511-1.1	V545I	Pathogenic	0.615
SLC26A4	O43511-1.1	V545K	Pathogenic	0.944
SLC26A4	O43511-1.1	V545L	Pathogenic	0.87
SLC26A4	O43511-1.1	V545M	Pathogenic	0.889
SLC26A4	O43511-1.1	V545N	Pathogenic	0.99
SLC26A4	O43511-1.1	V545P	Pathogenic	0.985
SLC26A4	O43511-1.1	V545Q	Pathogenic	0.983
SLC26A4	O43511-1.1	V545R	Pathogenic	0.95
SLC26A4	O43511-1.1	V545S	Pathogenic	0.957
SLC26A4	O43511-1.1	V545T	Pathogenic	0.939
SLC26A4	O43511-1.1	V545W	Pathogenic	0.938
SLC26A4	O43511-1.1	V545Y	Pathogenic	0.932
SLC26A4	O43511-1.1	K546A	Pathogenic	0.96
SLC26A4	O43511-1.1	K546C	Pathogenic	0.994
SLC26A4	O43511-1.1	K546D	Pathogenic	0.991
SLC26A4	O43511-1.1	K546E	Pathogenic	0.983
SLC26A4	O43511-1.1	K546F	Pathogenic	0.999
SLC26A4	O43511-1.1	K546G	Pathogenic	0.958
SLC26A4	O43511-1.1	K546H	Pathogenic	0.996
SLC26A4	O43511-1.1	K546I	Pathogenic	0.999
SLC26A4	O43511-1.1	K546L	Pathogenic	0.997
SLC26A4	O43511-1.1	K546M	Pathogenic	0.995
SLC26A4	O43511-1.1	K546N	Pathogenic	0.984
SLC26A4	O43511-1.1	K546P	Pathogenic	0.983
SLC26A4	O43511-1.1	K546Q	Pathogenic	0.984
SLC26A4	O43511-1.1	K546R	Pathogenic	0.983
SLC26A4	O43511-1.1	K546S	Pathogenic	0.947
SLC26A4	O43511-1.1	K546T	Pathogenic	0.988
SLC26A4	O43511-1.1	K546V	Pathogenic	0.995
SLC26A4	O43511-1.1	K546W	Pathogenic	0.996
SLC26A4	O43511-1.1	K546Y	Pathogenic	0.998
SLC26A4	O43511-1.1	I547A	Pathogenic	0.955
SLC26A4	O43511-1.1	I547C	Pathogenic	0.985
SLC26A4	O43511-1.1	I547D	Pathogenic	0.994
SLC26A4	O43511-1.1	I547E	Pathogenic	0.997
SLC26A4	O43511-1.1	I547F	Pathogenic	0.993
SLC26A4	O43511-1.1	I547G	Pathogenic	0.985
SLC26A4	O43511-1.1	I547H	Pathogenic	0.999
SLC26A4	O43511-1.1	I547K	Pathogenic	0.998
SLC26A4	O43511-1.1	I547L	Pathogenic	0.983
SLC26A4	O43511-1.1	I547M	Pathogenic	0.99
SLC26A4	O43511-1.1	I547N	Pathogenic	0.996
SLC26A4	O43511-1.1	I547P	Pathogenic	0.996
SLC26A4	O43511-1.1	I547Q	Pathogenic	0.998
SLC26A4	O43511-1.1	I547R	Pathogenic	0.996
SLC26A4	O43511-1.1	I547S	Pathogenic	0.98
SLC26A4	O43511-1.1	I547T	Pathogenic	0.985
SLC26A4	O43511-1.1	I547V	Pathogenic	0.911
SLC26A4	O43511-1.1	I547W	Pathogenic	0.997
SLC26A4	O43511-1.1	I547Y	Pathogenic	0.994
SLC26A4	O43511-1.1	L548A	Neutral	0.203
SLC26A4	O43511-1.1	L548C	Neutral	0.438
SLC26A4	O43511-1.1	L548D	Pathogenic	0.801
SLC26A4	O43511-1.1	L548E	Pathogenic	0.826
SLC26A4	O43511-1.1	L548F	Pathogenic	0.626
SLC26A4	O43511-1.1	L548G	Neutral	0.438
SLC26A4	O43511-1.1	L548H	Pathogenic	0.906
SLC26A4	O43511-1.1	L548I	Neutral	0.404
SLC26A4	O43511-1.1	L548K	Pathogenic	0.713
SLC26A4	O43511-1.1	L548M	Neutral	0.371
SLC26A4	O43511-1.1	L548N	Pathogenic	0.729
SLC26A4	O43511-1.1	L548P	Pathogenic	0.773
SLC26A4	O43511-1.1	L548Q	Pathogenic	0.777
SLC26A4	O43511-1.1	L548R	Pathogenic	0.578
SLC26A4	O43511-1.1	L548S	Neutral	0.371
SLC26A4	O43511-1.1	L548T	Neutral	0.447
SLC26A4	O43511-1.1	L548V	Neutral	0.333
SLC26A4	O43511-1.1	L548W	Pathogenic	0.615
SLC26A4	O43511-1.1	L548Y	Pathogenic	0.666
SLC26A4	O43511-1.1	R549A	Pathogenic	0.797
SLC26A4	O43511-1.1	R549C	Pathogenic	0.966
SLC26A4	O43511-1.1	R549D	Pathogenic	0.972
SLC26A4	O43511-1.1	R549E	Pathogenic	0.949
SLC26A4	O43511-1.1	R549F	Pathogenic	0.995
SLC26A4	O43511-1.1	R549G	Pathogenic	0.79
SLC26A4	O43511-1.1	R549H	Pathogenic	0.954
SLC26A4	O43511-1.1	R549I	Pathogenic	0.991
SLC26A4	O43511-1.1	R549K	Pathogenic	0.945
SLC26A4	O43511-1.1	R549L	Pathogenic	0.984
SLC26A4	O43511-1.1	R549M	Pathogenic	0.973
SLC26A4	O43511-1.1	R549N	Pathogenic	0.911
SLC26A4	O43511-1.1	R549P	Pathogenic	0.95
SLC26A4	O43511-1.1	R549Q	Pathogenic	0.908
SLC26A4	O43511-1.1	R549S	Pathogenic	0.854
SLC26A4	O43511-1.1	R549T	Pathogenic	0.928
SLC26A4	O43511-1.1	R549V	Pathogenic	0.984
SLC26A4	O43511-1.1	R549W	Pathogenic	0.993
SLC26A4	O43511-1.1	R549Y	Pathogenic	0.994
SLC26A4	O43511-1.1	F550A	Neutral	0.265
SLC26A4	O43511-1.1	F550C	Pathogenic	0.525
SLC26A4	O43511-1.1	F550D	Pathogenic	0.586
SLC26A4	O43511-1.1	F550E	Pathogenic	0.77
SLC26A4	O43511-1.1	F550G	Neutral	0.215
SLC26A4	O43511-1.1	F550H	Pathogenic	0.627
SLC26A4	O43511-1.1	F550I	Pathogenic	0.674
SLC26A4	O43511-1.1	F550K	Pathogenic	0.905
SLC26A4	O43511-1.1	F550L	Pathogenic	0.667
SLC26A4	O43511-1.1	F550M	Pathogenic	0.626
SLC26A4	O43511-1.1	F550N	Pathogenic	0.654
SLC26A4	O43511-1.1	F550P	Pathogenic	0.828
SLC26A4	O43511-1.1	F550Q	Pathogenic	0.832
SLC26A4	O43511-1.1	F550R	Pathogenic	0.84
SLC26A4	O43511-1.1	F550S	Neutral	0.293
SLC26A4	O43511-1.1	F550T	Pathogenic	0.534
SLC26A4	O43511-1.1	F550V	Pathogenic	0.587
SLC26A4	O43511-1.1	F550W	Neutral	0.286
SLC26A4	O43511-1.1	F550Y	Neutral	0.189
SLC26A4	O43511-1.1	S551A	Pathogenic	0.688
SLC26A4	O43511-1.1	S551C	Pathogenic	0.833
SLC26A4	O43511-1.1	S551D	Pathogenic	0.689
SLC26A4	O43511-1.1	S551E	Pathogenic	0.509
SLC26A4	O43511-1.1	S551F	Neutral	0.447
SLC26A4	O43511-1.1	S551G	Pathogenic	0.679
SLC26A4	O43511-1.1	S551H	Pathogenic	0.621
SLC26A4	O43511-1.1	S551I	Pathogenic	0.569
SLC26A4	O43511-1.1	S551K	Neutral	0.219
SLC26A4	O43511-1.1	S551L	Pathogenic	0.578
SLC26A4	O43511-1.1	S551M	Neutral	0.45
SLC26A4	O43511-1.1	S551N	Neutral	0.485
SLC26A4	O43511-1.1	S551P	Pathogenic	0.822
SLC26A4	O43511-1.1	S551Q	Neutral	0.493
SLC26A4	O43511-1.1	S551R	Neutral	0.237
SLC26A4	O43511-1.1	S551T	Pathogenic	0.545
SLC26A4	O43511-1.1	S551V	Pathogenic	0.796
SLC26A4	O43511-1.1	S551W	Neutral	0.277
SLC26A4	O43511-1.1	S551Y	Neutral	0.459
SLC26A4	O43511-1.1	S552A	Pathogenic	0.915
SLC26A4	O43511-1.1	S552C	Pathogenic	0.961
SLC26A4	O43511-1.1	S552D	Pathogenic	0.916
SLC26A4	O43511-1.1	S552E	Pathogenic	0.836
SLC26A4	O43511-1.1	S552F	Pathogenic	0.798
SLC26A4	O43511-1.1	S552G	Pathogenic	0.912
SLC26A4	O43511-1.1	S552H	Pathogenic	0.889
SLC26A4	O43511-1.1	S552I	Pathogenic	0.866
SLC26A4	O43511-1.1	S552K	Pathogenic	0.578
SLC26A4	O43511-1.1	S552L	Pathogenic	0.871
SLC26A4	O43511-1.1	S552M	Pathogenic	0.8
SLC26A4	O43511-1.1	S552N	Pathogenic	0.822
SLC26A4	O43511-1.1	S552P	Pathogenic	0.958
SLC26A4	O43511-1.1	S552Q	Pathogenic	0.827
SLC26A4	O43511-1.1	S552R	Pathogenic	0.604
SLC26A4	O43511-1.1	S552T	Pathogenic	0.854
SLC26A4	O43511-1.1	S552V	Pathogenic	0.95
SLC26A4	O43511-1.1	S552W	Pathogenic	0.653
SLC26A4	O43511-1.1	S552Y	Pathogenic	0.806
SLC26A4	O43511-1.1	P553A	Pathogenic	0.995
SLC26A4	O43511-1.1	P553C	Pathogenic	0.999
SLC26A4	O43511-1.1	P553D	Pathogenic	0.997
SLC26A4	O43511-1.1	P553E	Pathogenic	0.994
SLC26A4	O43511-1.1	P553F	Pathogenic	0.998
SLC26A4	O43511-1.1	P553G	Pathogenic	0.993
SLC26A4	O43511-1.1	P553H	Pathogenic	0.996
SLC26A4	O43511-1.1	P553I	Pathogenic	0.997
SLC26A4	O43511-1.1	P553K	Pathogenic	0.976
SLC26A4	O43511-1.1	P553L	Pathogenic	0.997
SLC26A4	O43511-1.1	P553M	Pathogenic	0.995
SLC26A4	O43511-1.1	P553N	Pathogenic	0.998
SLC26A4	O43511-1.1	P553Q	Pathogenic	0.993
SLC26A4	O43511-1.1	P553R	Pathogenic	0.979
SLC26A4	O43511-1.1	P553S	Pathogenic	0.995
SLC26A4	O43511-1.1	P553T	Pathogenic	0.998
SLC26A4	O43511-1.1	P553V	Pathogenic	0.998
SLC26A4	O43511-1.1	P553W	Pathogenic	0.99
SLC26A4	O43511-1.1	P553Y	Pathogenic	0.996
SLC26A4	O43511-1.1	I554A	Pathogenic	0.795
SLC26A4	O43511-1.1	I554C	Pathogenic	0.922
SLC26A4	O43511-1.1	I554D	Pathogenic	0.968
SLC26A4	O43511-1.1	I554E	Pathogenic	0.986
SLC26A4	O43511-1.1	I554F	Pathogenic	0.965
SLC26A4	O43511-1.1	I554G	Pathogenic	0.922
SLC26A4	O43511-1.1	I554H	Pathogenic	0.993
SLC26A4	O43511-1.1	I554K	Pathogenic	0.987
SLC26A4	O43511-1.1	I554L	Pathogenic	0.915
SLC26A4	O43511-1.1	I554M	Pathogenic	0.947
SLC26A4	O43511-1.1	I554N	Pathogenic	0.976
SLC26A4	O43511-1.1	I554P	Pathogenic	0.981
SLC26A4	O43511-1.1	I554Q	Pathogenic	0.991
SLC26A4	O43511-1.1	I554R	Pathogenic	0.977
SLC26A4	O43511-1.1	I554S	Pathogenic	0.9
SLC26A4	O43511-1.1	I554T	Pathogenic	0.925
SLC26A4	O43511-1.1	I554V	Pathogenic	0.653
SLC26A4	O43511-1.1	I554W	Pathogenic	0.981
SLC26A4	O43511-1.1	I554Y	Pathogenic	0.968
SLC26A4	O43511-1.1	F555A	Pathogenic	0.842
SLC26A4	O43511-1.1	F555C	Pathogenic	0.942
SLC26A4	O43511-1.1	F555D	Pathogenic	0.954
SLC26A4	O43511-1.1	F555E	Pathogenic	0.98
SLC26A4	O43511-1.1	F555G	Pathogenic	0.802
SLC26A4	O43511-1.1	F555H	Pathogenic	0.961
SLC26A4	O43511-1.1	F555I	Pathogenic	0.968
SLC26A4	O43511-1.1	F555K	Pathogenic	0.993
SLC26A4	O43511-1.1	F555L	Pathogenic	0.967
SLC26A4	O43511-1.1	F555M	Pathogenic	0.961
SLC26A4	O43511-1.1	F555N	Pathogenic	0.965
SLC26A4	O43511-1.1	F555P	Pathogenic	0.986
SLC26A4	O43511-1.1	F555Q	Pathogenic	0.986
SLC26A4	O43511-1.1	F555R	Pathogenic	0.987
SLC26A4	O43511-1.1	F555S	Pathogenic	0.86
SLC26A4	O43511-1.1	F555T	Pathogenic	0.944
SLC26A4	O43511-1.1	F555V	Pathogenic	0.954
SLC26A4	O43511-1.1	F555W	Pathogenic	0.856
SLC26A4	O43511-1.1	F555Y	Pathogenic	0.775
SLC26A4	O43511-1.1	Y556A	Pathogenic	0.874
SLC26A4	O43511-1.1	Y556C	Pathogenic	0.954
SLC26A4	O43511-1.1	Y556D	Pathogenic	0.965
SLC26A4	O43511-1.1	Y556E	Pathogenic	0.97
SLC26A4	O43511-1.1	Y556F	Pathogenic	0.81
SLC26A4	O43511-1.1	Y556G	Pathogenic	0.84
SLC26A4	O43511-1.1	Y556H	Pathogenic	0.799
SLC26A4	O43511-1.1	Y556I	Pathogenic	0.977
SLC26A4	O43511-1.1	Y556K	Pathogenic	0.989
SLC26A4	O43511-1.1	Y556L	Pathogenic	0.978
SLC26A4	O43511-1.1	Y556M	Pathogenic	0.981
SLC26A4	O43511-1.1	Y556N	Pathogenic	0.948
SLC26A4	O43511-1.1	Y556P	Pathogenic	0.979
SLC26A4	O43511-1.1	Y556Q	Pathogenic	0.959
SLC26A4	O43511-1.1	Y556R	Pathogenic	0.989
SLC26A4	O43511-1.1	Y556S	Pathogenic	0.889
SLC26A4	O43511-1.1	Y556T	Pathogenic	0.957
SLC26A4	O43511-1.1	Y556V	Pathogenic	0.957
SLC26A4	O43511-1.1	Y556W	Pathogenic	0.777
SLC26A4	O43511-1.1	G557A	Pathogenic	0.762
SLC26A4	O43511-1.1	G557C	Pathogenic	0.895
SLC26A4	O43511-1.1	G557D	Pathogenic	0.646
SLC26A4	O43511-1.1	G557E	Pathogenic	0.631
SLC26A4	O43511-1.1	G557F	Neutral	0.405
SLC26A4	O43511-1.1	G557H	Pathogenic	0.581
SLC26A4	O43511-1.1	G557I	Pathogenic	0.691
SLC26A4	O43511-1.1	G557K	Neutral	0.316
SLC26A4	O43511-1.1	G557L	Pathogenic	0.7
SLC26A4	O43511-1.1	G557M	Pathogenic	0.581
SLC26A4	O43511-1.1	G557N	Neutral	0.436
SLC26A4	O43511-1.1	G557P	Pathogenic	0.796
SLC26A4	O43511-1.1	G557Q	Pathogenic	0.616
SLC26A4	O43511-1.1	G557R	Neutral	0.203
SLC26A4	O43511-1.1	G557S	Pathogenic	0.731
SLC26A4	O43511-1.1	G557T	Pathogenic	0.803
SLC26A4	O43511-1.1	G557V	Pathogenic	0.767
SLC26A4	O43511-1.1	G557W	Neutral	0.074
SLC26A4	O43511-1.1	G557Y	Neutral	0.417
SLC26A4	O43511-1.1	N558A	Pathogenic	0.999
SLC26A4	O43511-1.1	N558C	Pathogenic	1.0
SLC26A4	O43511-1.1	N558D	Pathogenic	0.998
SLC26A4	O43511-1.1	N558E	Pathogenic	0.998
SLC26A4	O43511-1.1	N558F	Pathogenic	0.998
SLC26A4	O43511-1.1	N558G	Pathogenic	0.99
SLC26A4	O43511-1.1	N558H	Pathogenic	0.993
SLC26A4	O43511-1.1	N558I	Pathogenic	0.999
SLC26A4	O43511-1.1	N558K	Pathogenic	0.994
SLC26A4	O43511-1.1	N558L	Pathogenic	0.999
SLC26A4	O43511-1.1	N558M	Pathogenic	0.998
SLC26A4	O43511-1.1	N558P	Pathogenic	1.0
SLC26A4	O43511-1.1	N558Q	Pathogenic	0.998
SLC26A4	O43511-1.1	N558R	Pathogenic	0.989
SLC26A4	O43511-1.1	N558S	Pathogenic	0.994
SLC26A4	O43511-1.1	N558T	Pathogenic	0.999
SLC26A4	O43511-1.1	N558V	Pathogenic	1.0
SLC26A4	O43511-1.1	N558W	Pathogenic	0.997
SLC26A4	O43511-1.1	N558Y	Pathogenic	0.997
SLC26A4	O43511-1.1	V559A	Neutral	0.15
SLC26A4	O43511-1.1	V559C	Pathogenic	0.521
SLC26A4	O43511-1.1	V559D	Pathogenic	0.737
SLC26A4	O43511-1.1	V559E	Pathogenic	0.697
SLC26A4	O43511-1.1	V559F	Neutral	0.367
SLC26A4	O43511-1.1	V559G	Neutral	0.351
SLC26A4	O43511-1.1	V559H	Pathogenic	0.805
SLC26A4	O43511-1.1	V559I	Neutral	0.055
SLC26A4	O43511-1.1	V559K	Neutral	0.383
SLC26A4	O43511-1.1	V559L	Neutral	0.196
SLC26A4	O43511-1.1	V559M	Neutral	0.227
SLC26A4	O43511-1.1	V559N	Pathogenic	0.789
SLC26A4	O43511-1.1	V559P	Pathogenic	0.702
SLC26A4	O43511-1.1	V559Q	Pathogenic	0.683
SLC26A4	O43511-1.1	V559R	Neutral	0.408
SLC26A4	O43511-1.1	V559S	Neutral	0.45
SLC26A4	O43511-1.1	V559T	Neutral	0.359
SLC26A4	O43511-1.1	V559W	Neutral	0.357
SLC26A4	O43511-1.1	V559Y	Neutral	0.333
SLC26A4	O43511-1.1	D560A	Pathogenic	0.873
SLC26A4	O43511-1.1	D560C	Pathogenic	0.962
SLC26A4	O43511-1.1	D560E	Neutral	0.443
SLC26A4	O43511-1.1	D560F	Pathogenic	0.759
SLC26A4	O43511-1.1	D560G	Pathogenic	0.62
SLC26A4	O43511-1.1	D560H	Pathogenic	0.761
SLC26A4	O43511-1.1	D560I	Pathogenic	0.837
SLC26A4	O43511-1.1	D560K	Pathogenic	0.658
SLC26A4	O43511-1.1	D560L	Pathogenic	0.915
SLC26A4	O43511-1.1	D560M	Pathogenic	0.865
SLC26A4	O43511-1.1	D560N	Pathogenic	0.739
SLC26A4	O43511-1.1	D560P	Pathogenic	0.892
SLC26A4	O43511-1.1	D560Q	Pathogenic	0.685
SLC26A4	O43511-1.1	D560R	Pathogenic	0.681
SLC26A4	O43511-1.1	D560S	Pathogenic	0.718
SLC26A4	O43511-1.1	D560T	Pathogenic	0.904
SLC26A4	O43511-1.1	D560V	Pathogenic	0.938
SLC26A4	O43511-1.1	D560W	Pathogenic	0.6
SLC26A4	O43511-1.1	D560Y	Pathogenic	0.768
SLC26A4	O43511-1.1	G561A	Pathogenic	0.642
SLC26A4	O43511-1.1	G561C	Pathogenic	0.826
SLC26A4	O43511-1.1	G561D	Pathogenic	0.505
SLC26A4	O43511-1.1	G561E	Neutral	0.489
SLC26A4	O43511-1.1	G561F	Neutral	0.276
SLC26A4	O43511-1.1	G561H	Neutral	0.436
SLC26A4	O43511-1.1	G561I	Pathogenic	0.556
SLC26A4	O43511-1.1	G561K	Neutral	0.205
SLC26A4	O43511-1.1	G561L	Pathogenic	0.566
SLC26A4	O43511-1.1	G561M	Neutral	0.437
SLC26A4	O43511-1.1	G561N	Neutral	0.302
SLC26A4	O43511-1.1	G561P	Pathogenic	0.686
SLC26A4	O43511-1.1	G561Q	Neutral	0.473
SLC26A4	O43511-1.1	G561R	Neutral	0.125
SLC26A4	O43511-1.1	G561S	Pathogenic	0.603
SLC26A4	O43511-1.1	G561T	Pathogenic	0.695
SLC26A4	O43511-1.1	G561V	Pathogenic	0.648
SLC26A4	O43511-1.1	G561W	Neutral	0.043
SLC26A4	O43511-1.1	G561Y	Neutral	0.286
SLC26A4	O43511-1.1	F562A	Pathogenic	0.758
SLC26A4	O43511-1.1	F562C	Pathogenic	0.906
SLC26A4	O43511-1.1	F562D	Pathogenic	0.925
SLC26A4	O43511-1.1	F562E	Pathogenic	0.967
SLC26A4	O43511-1.1	F562G	Pathogenic	0.704
SLC26A4	O43511-1.1	F562H	Pathogenic	0.936
SLC26A4	O43511-1.1	F562I	Pathogenic	0.947
SLC26A4	O43511-1.1	F562K	Pathogenic	0.988
SLC26A4	O43511-1.1	F562L	Pathogenic	0.946
SLC26A4	O43511-1.1	F562M	Pathogenic	0.936
SLC26A4	O43511-1.1	F562N	Pathogenic	0.943
SLC26A4	O43511-1.1	F562P	Pathogenic	0.977
SLC26A4	O43511-1.1	F562Q	Pathogenic	0.977
SLC26A4	O43511-1.1	F562R	Pathogenic	0.978
SLC26A4	O43511-1.1	F562S	Pathogenic	0.783
SLC26A4	O43511-1.1	F562T	Pathogenic	0.909
SLC26A4	O43511-1.1	F562V	Pathogenic	0.925
SLC26A4	O43511-1.1	F562W	Pathogenic	0.777
SLC26A4	O43511-1.1	F562Y	Pathogenic	0.669
SLC26A4	O43511-1.1	K563A	Pathogenic	0.512
SLC26A4	O43511-1.1	K563C	Pathogenic	0.885
SLC26A4	O43511-1.1	K563D	Pathogenic	0.825
SLC26A4	O43511-1.1	K563E	Pathogenic	0.714
SLC26A4	O43511-1.1	K563F	Pathogenic	0.981
SLC26A4	O43511-1.1	K563G	Pathogenic	0.502
SLC26A4	O43511-1.1	K563H	Pathogenic	0.918
SLC26A4	O43511-1.1	K563I	Pathogenic	0.969
SLC26A4	O43511-1.1	K563L	Pathogenic	0.942
SLC26A4	O43511-1.1	K563M	Pathogenic	0.906
SLC26A4	O43511-1.1	K563N	Pathogenic	0.733
SLC26A4	O43511-1.1	K563P	Pathogenic	0.717
SLC26A4	O43511-1.1	K563Q	Pathogenic	0.727
SLC26A4	O43511-1.1	K563R	Pathogenic	0.718
SLC26A4	O43511-1.1	K563S	Neutral	0.439
SLC26A4	O43511-1.1	K563T	Pathogenic	0.776
SLC26A4	O43511-1.1	K563V	Pathogenic	0.892
SLC26A4	O43511-1.1	K563W	Pathogenic	0.924
SLC26A4	O43511-1.1	K563Y	Pathogenic	0.964
SLC26A4	O43511-1.1	K564A	Neutral	0.022
SLC26A4	O43511-1.1	K564C	Neutral	0.14
SLC26A4	O43511-1.1	K564D	Neutral	0.09
SLC26A4	O43511-1.1	K564E	Neutral	0.05
SLC26A4	O43511-1.1	K564F	Pathogenic	0.521
SLC26A4	O43511-1.1	K564G	Neutral	0.021
SLC26A4	O43511-1.1	K564H	Neutral	0.192
SLC26A4	O43511-1.1	K564I	Neutral	0.397
SLC26A4	O43511-1.1	K564L	Neutral	0.254
SLC26A4	O43511-1.1	K564M	Neutral	0.169
SLC26A4	O43511-1.1	K564N	Neutral	0.055
SLC26A4	O43511-1.1	K564P	Neutral	0.051
SLC26A4	O43511-1.1	K564Q	Neutral	0.053
SLC26A4	O43511-1.1	K564R	Neutral	0.051
SLC26A4	O43511-1.1	K564S	Neutral	0.016
SLC26A4	O43511-1.1	K564T	Neutral	0.068
SLC26A4	O43511-1.1	K564V	Neutral	0.149
SLC26A4	O43511-1.1	K564W	Neutral	0.205
SLC26A4	O43511-1.1	K564Y	Neutral	0.363
SLC26A4	O43511-1.1	C565A	Pathogenic	0.889
SLC26A4	O43511-1.1	C565D	Pathogenic	0.988
SLC26A4	O43511-1.1	C565E	Pathogenic	0.987
SLC26A4	O43511-1.1	C565F	Pathogenic	0.888
SLC26A4	O43511-1.1	C565G	Pathogenic	0.961
SLC26A4	O43511-1.1	C565H	Pathogenic	0.971
SLC26A4	O43511-1.1	C565I	Pathogenic	0.866
SLC26A4	O43511-1.1	C565K	Pathogenic	0.911
SLC26A4	O43511-1.1	C565L	Pathogenic	0.871
SLC26A4	O43511-1.1	C565M	Pathogenic	0.89
SLC26A4	O43511-1.1	C565N	Pathogenic	0.986
SLC26A4	O43511-1.1	C565P	Pathogenic	0.993
SLC26A4	O43511-1.1	C565Q	Pathogenic	0.973
SLC26A4	O43511-1.1	C565R	Pathogenic	0.849
SLC26A4	O43511-1.1	C565S	Pathogenic	0.949
SLC26A4	O43511-1.1	C565T	Pathogenic	0.965
SLC26A4	O43511-1.1	C565V	Pathogenic	0.95
SLC26A4	O43511-1.1	C565W	Pathogenic	0.653
SLC26A4	O43511-1.1	C565Y	Pathogenic	0.891
SLC26A4	O43511-1.1	I566A	Neutral	0.187
SLC26A4	O43511-1.1	I566C	Neutral	0.412
SLC26A4	O43511-1.1	I566D	Pathogenic	0.643
SLC26A4	O43511-1.1	I566E	Pathogenic	0.811
SLC26A4	O43511-1.1	I566F	Pathogenic	0.617
SLC26A4	O43511-1.1	I566G	Neutral	0.412
SLC26A4	O43511-1.1	I566H	Pathogenic	0.896
SLC26A4	O43511-1.1	I566K	Pathogenic	0.817
SLC26A4	O43511-1.1	I566L	Neutral	0.388
SLC26A4	O43511-1.1	I566M	Pathogenic	0.515
SLC26A4	O43511-1.1	I566N	Pathogenic	0.707
SLC26A4	O43511-1.1	I566P	Pathogenic	0.754
SLC26A4	O43511-1.1	I566Q	Pathogenic	0.863
SLC26A4	O43511-1.1	I566R	Pathogenic	0.712
SLC26A4	O43511-1.1	I566S	Neutral	0.346
SLC26A4	O43511-1.1	I566T	Neutral	0.421
SLC26A4	O43511-1.1	I566V	Neutral	0.1
SLC26A4	O43511-1.1	I566W	Pathogenic	0.757
SLC26A4	O43511-1.1	I566Y	Pathogenic	0.642
SLC26A4	O43511-1.1	K567A	Neutral	0.213
SLC26A4	O43511-1.1	K567C	Pathogenic	0.665
SLC26A4	O43511-1.1	K567D	Pathogenic	0.547
SLC26A4	O43511-1.1	K567E	Neutral	0.391
SLC26A4	O43511-1.1	K567F	Pathogenic	0.93
SLC26A4	O43511-1.1	K567G	Neutral	0.206
SLC26A4	O43511-1.1	K567H	Pathogenic	0.743
SLC26A4	O43511-1.1	K567I	Pathogenic	0.889
SLC26A4	O43511-1.1	K567L	Pathogenic	0.806
SLC26A4	O43511-1.1	K567M	Pathogenic	0.713
SLC26A4	O43511-1.1	K567N	Neutral	0.414
SLC26A4	O43511-1.1	K567P	Neutral	0.394
SLC26A4	O43511-1.1	K567Q	Neutral	0.406
SLC26A4	O43511-1.1	K567R	Neutral	0.395
SLC26A4	O43511-1.1	K567S	Neutral	0.168
SLC26A4	O43511-1.1	K567T	Neutral	0.471
SLC26A4	O43511-1.1	K567V	Pathogenic	0.68
SLC26A4	O43511-1.1	K567W	Pathogenic	0.758
SLC26A4	O43511-1.1	K567Y	Pathogenic	0.874
SLC26A4	O43511-1.1	S568A	Neutral	0.288
SLC26A4	O43511-1.1	S568C	Neutral	0.479
SLC26A4	O43511-1.1	S568D	Neutral	0.29
SLC26A4	O43511-1.1	S568E	Neutral	0.16
SLC26A4	O43511-1.1	S568F	Neutral	0.129
SLC26A4	O43511-1.1	S568G	Neutral	0.28
SLC26A4	O43511-1.1	S568H	Neutral	0.231
SLC26A4	O43511-1.1	S568I	Neutral	0.195
SLC26A4	O43511-1.1	S568K	Neutral	0.049
SLC26A4	O43511-1.1	S568L	Neutral	0.201
SLC26A4	O43511-1.1	S568M	Neutral	0.131
SLC26A4	O43511-1.1	S568N	Neutral	0.147
SLC26A4	O43511-1.1	S568P	Neutral	0.459
SLC26A4	O43511-1.1	S568Q	Neutral	0.151
SLC26A4	O43511-1.1	S568R	Neutral	0.054
SLC26A4	O43511-1.1	S568T	Neutral	0.18
SLC26A4	O43511-1.1	S568V	Neutral	0.417
SLC26A4	O43511-1.1	S568W	Neutral	0.066
SLC26A4	O43511-1.1	S568Y	Neutral	0.135
SLC26A4	O43511-1.1	T569A	Pathogenic	0.689
SLC26A4	O43511-1.1	T569C	Pathogenic	0.89
SLC26A4	O43511-1.1	T569D	Pathogenic	0.9
SLC26A4	O43511-1.1	T569E	Pathogenic	0.835
SLC26A4	O43511-1.1	T569F	Pathogenic	0.71
SLC26A4	O43511-1.1	T569G	Pathogenic	0.778
SLC26A4	O43511-1.1	T569H	Pathogenic	0.901
SLC26A4	O43511-1.1	T569I	Pathogenic	0.666
SLC26A4	O43511-1.1	T569K	Pathogenic	0.577
SLC26A4	O43511-1.1	T569L	Pathogenic	0.675
SLC26A4	O43511-1.1	T569M	Pathogenic	0.713
SLC26A4	O43511-1.1	T569N	Pathogenic	0.821
SLC26A4	O43511-1.1	T569P	Pathogenic	0.915
SLC26A4	O43511-1.1	T569Q	Pathogenic	0.825
SLC26A4	O43511-1.1	T569R	Neutral	0.43
SLC26A4	O43511-1.1	T569S	Pathogenic	0.568
SLC26A4	O43511-1.1	T569V	Pathogenic	0.746
SLC26A4	O43511-1.1	T569W	Neutral	0.367
SLC26A4	O43511-1.1	T569Y	Pathogenic	0.72
SLC26A4	O43511-1.1	V570A	Pathogenic	0.856
SLC26A4	O43511-1.1	V570C	Pathogenic	0.973
SLC26A4	O43511-1.1	V570D	Pathogenic	0.989
SLC26A4	O43511-1.1	V570E	Pathogenic	0.987
SLC26A4	O43511-1.1	V570F	Pathogenic	0.951
SLC26A4	O43511-1.1	V570G	Pathogenic	0.948
SLC26A4	O43511-1.1	V570H	Pathogenic	0.993
SLC26A4	O43511-1.1	V570I	Pathogenic	0.661
SLC26A4	O43511-1.1	V570K	Pathogenic	0.954
SLC26A4	O43511-1.1	V570L	Pathogenic	0.891
SLC26A4	O43511-1.1	V570M	Pathogenic	0.908
SLC26A4	O43511-1.1	V570N	Pathogenic	0.992
SLC26A4	O43511-1.1	V570P	Pathogenic	0.988
SLC26A4	O43511-1.1	V570Q	Pathogenic	0.986
SLC26A4	O43511-1.1	V570R	Pathogenic	0.959
SLC26A4	O43511-1.1	V570S	Pathogenic	0.965
SLC26A4	O43511-1.1	V570T	Pathogenic	0.949
SLC26A4	O43511-1.1	V570W	Pathogenic	0.949
SLC26A4	O43511-1.1	V570Y	Pathogenic	0.944
SLC26A4	O43511-1.1	G571A	Pathogenic	0.994
SLC26A4	O43511-1.1	G571C	Pathogenic	0.998
SLC26A4	O43511-1.1	G571D	Pathogenic	0.99
SLC26A4	O43511-1.1	G571E	Pathogenic	0.99
SLC26A4	O43511-1.1	G571F	Pathogenic	0.974
SLC26A4	O43511-1.1	G571H	Pathogenic	0.987
SLC26A4	O43511-1.1	G571I	Pathogenic	0.992
SLC26A4	O43511-1.1	G571K	Pathogenic	0.963
SLC26A4	O43511-1.1	G571L	Pathogenic	0.992
SLC26A4	O43511-1.1	G571M	Pathogenic	0.987
SLC26A4	O43511-1.1	G571N	Pathogenic	0.977
SLC26A4	O43511-1.1	G571P	Pathogenic	0.995
SLC26A4	O43511-1.1	G571Q	Pathogenic	0.989
SLC26A4	O43511-1.1	G571R	Pathogenic	0.935
SLC26A4	O43511-1.1	G571S	Pathogenic	0.993
SLC26A4	O43511-1.1	G571T	Pathogenic	0.996
SLC26A4	O43511-1.1	G571V	Pathogenic	0.995
SLC26A4	O43511-1.1	G571W	Pathogenic	0.818
SLC26A4	O43511-1.1	G571Y	Pathogenic	0.976
SLC26A4	O43511-1.1	F572A	Pathogenic	0.956
SLC26A4	O43511-1.1	F572C	Pathogenic	0.985
SLC26A4	O43511-1.1	F572D	Pathogenic	0.988
SLC26A4	O43511-1.1	F572E	Pathogenic	0.995
SLC26A4	O43511-1.1	F572G	Pathogenic	0.943
SLC26A4	O43511-1.1	F572H	Pathogenic	0.99
SLC26A4	O43511-1.1	F572I	Pathogenic	0.992
SLC26A4	O43511-1.1	F572K	Pathogenic	0.998
SLC26A4	O43511-1.1	F572L	Pathogenic	0.992
SLC26A4	O43511-1.1	F572M	Pathogenic	0.99
SLC26A4	O43511-1.1	F572N	Pathogenic	0.991
SLC26A4	O43511-1.1	F572P	Pathogenic	0.997
SLC26A4	O43511-1.1	F572Q	Pathogenic	0.997
SLC26A4	O43511-1.1	F572R	Pathogenic	0.997
SLC26A4	O43511-1.1	F572S	Pathogenic	0.962
SLC26A4	O43511-1.1	F572T	Pathogenic	0.986
SLC26A4	O43511-1.1	F572V	Pathogenic	0.988
SLC26A4	O43511-1.1	F572W	Pathogenic	0.96
SLC26A4	O43511-1.1	F572Y	Pathogenic	0.934
SLC26A4	O43511-1.1	D573A	Pathogenic	0.916
SLC26A4	O43511-1.1	D573C	Pathogenic	0.976
SLC26A4	O43511-1.1	D573E	Pathogenic	0.56
SLC26A4	O43511-1.1	D573F	Pathogenic	0.835
SLC26A4	O43511-1.1	D573G	Pathogenic	0.723
SLC26A4	O43511-1.1	D573H	Pathogenic	0.836
SLC26A4	O43511-1.1	D573I	Pathogenic	0.892
SLC26A4	O43511-1.1	D573K	Pathogenic	0.755
SLC26A4	O43511-1.1	D573L	Pathogenic	0.945
SLC26A4	O43511-1.1	D573M	Pathogenic	0.911
SLC26A4	O43511-1.1	D573N	Pathogenic	0.819
SLC26A4	O43511-1.1	D573P	Pathogenic	0.929
SLC26A4	O43511-1.1	D573Q	Pathogenic	0.777
SLC26A4	O43511-1.1	D573R	Pathogenic	0.774
SLC26A4	O43511-1.1	D573S	Pathogenic	0.803
SLC26A4	O43511-1.1	D573T	Pathogenic	0.938
SLC26A4	O43511-1.1	D573V	Pathogenic	0.961
SLC26A4	O43511-1.1	D573W	Pathogenic	0.706
SLC26A4	O43511-1.1	D573Y	Pathogenic	0.841
SLC26A4	O43511-1.1	A574C	Pathogenic	0.77
SLC26A4	O43511-1.1	A574D	Pathogenic	0.902
SLC26A4	O43511-1.1	A574E	Pathogenic	0.682
SLC26A4	O43511-1.1	A574F	Pathogenic	0.52
SLC26A4	O43511-1.1	A574G	Pathogenic	0.794
SLC26A4	O43511-1.1	A574H	Pathogenic	0.794
SLC26A4	O43511-1.1	A574I	Neutral	0.468
SLC26A4	O43511-1.1	A574K	Neutral	0.366
SLC26A4	O43511-1.1	A574L	Neutral	0.478
SLC26A4	O43511-1.1	A574M	Pathogenic	0.523
SLC26A4	O43511-1.1	A574N	Pathogenic	0.887
SLC26A4	O43511-1.1	A574P	Pathogenic	0.861
SLC26A4	O43511-1.1	A574Q	Pathogenic	0.668
SLC26A4	O43511-1.1	A574R	Neutral	0.242
SLC26A4	O43511-1.1	A574S	Pathogenic	0.773
SLC26A4	O43511-1.1	A574T	Pathogenic	0.756
SLC26A4	O43511-1.1	A574V	Pathogenic	0.564
SLC26A4	O43511-1.1	A574W	Neutral	0.34
SLC26A4	O43511-1.1	A574Y	Pathogenic	0.532
SLC26A4	O43511-1.1	I575A	Neutral	0.032
SLC26A4	O43511-1.1	I575C	Neutral	0.091
SLC26A4	O43511-1.1	I575D	Neutral	0.206
SLC26A4	O43511-1.1	I575E	Neutral	0.381
SLC26A4	O43511-1.1	I575F	Neutral	0.188
SLC26A4	O43511-1.1	I575G	Neutral	0.091
SLC26A4	O43511-1.1	I575H	Pathogenic	0.554
SLC26A4	O43511-1.1	I575K	Neutral	0.391
SLC26A4	O43511-1.1	I575L	Neutral	0.083
SLC26A4	O43511-1.1	I575M	Neutral	0.132
SLC26A4	O43511-1.1	I575N	Neutral	0.257
SLC26A4	O43511-1.1	I575P	Neutral	0.305
SLC26A4	O43511-1.1	I575Q	Neutral	0.475
SLC26A4	O43511-1.1	I575R	Neutral	0.262
SLC26A4	O43511-1.1	I575S	Neutral	0.071
SLC26A4	O43511-1.1	I575T	Neutral	0.094
SLC26A4	O43511-1.1	I575V	Neutral	0.016
SLC26A4	O43511-1.1	I575W	Neutral	0.31
SLC26A4	O43511-1.1	I575Y	Neutral	0.205
SLC26A4	O43511-1.1	R576A	Pathogenic	0.819
SLC26A4	O43511-1.1	R576C	Pathogenic	0.971
SLC26A4	O43511-1.1	R576D	Pathogenic	0.976
SLC26A4	O43511-1.1	R576E	Pathogenic	0.956
SLC26A4	O43511-1.1	R576F	Pathogenic	0.996
SLC26A4	O43511-1.1	R576G	Pathogenic	0.813
SLC26A4	O43511-1.1	R576H	Pathogenic	0.96
SLC26A4	O43511-1.1	R576I	Pathogenic	0.993
SLC26A4	O43511-1.1	R576K	Pathogenic	0.952
SLC26A4	O43511-1.1	R576L	Pathogenic	0.986
SLC26A4	O43511-1.1	R576M	Pathogenic	0.977
SLC26A4	O43511-1.1	R576N	Pathogenic	0.922
SLC26A4	O43511-1.1	R576P	Pathogenic	0.956
SLC26A4	O43511-1.1	R576Q	Pathogenic	0.92
SLC26A4	O43511-1.1	R576S	Pathogenic	0.872
SLC26A4	O43511-1.1	R576T	Pathogenic	0.937
SLC26A4	O43511-1.1	R576V	Pathogenic	0.986
SLC26A4	O43511-1.1	R576W	Pathogenic	0.994
SLC26A4	O43511-1.1	R576Y	Pathogenic	0.995
SLC26A4	O43511-1.1	V577A	Pathogenic	0.731
SLC26A4	O43511-1.1	V577C	Pathogenic	0.943
SLC26A4	O43511-1.1	V577D	Pathogenic	0.977
SLC26A4	O43511-1.1	V577E	Pathogenic	0.972
SLC26A4	O43511-1.1	V577F	Pathogenic	0.899
SLC26A4	O43511-1.1	V577G	Pathogenic	0.893
SLC26A4	O43511-1.1	V577H	Pathogenic	0.985
SLC26A4	O43511-1.1	V577I	Neutral	0.472
SLC26A4	O43511-1.1	V577K	Pathogenic	0.905
SLC26A4	O43511-1.1	V577L	Pathogenic	0.79
SLC26A4	O43511-1.1	V577M	Pathogenic	0.818
SLC26A4	O43511-1.1	V577N	Pathogenic	0.983
SLC26A4	O43511-1.1	V577P	Pathogenic	0.973
SLC26A4	O43511-1.1	V577Q	Pathogenic	0.971
SLC26A4	O43511-1.1	V577R	Pathogenic	0.914
SLC26A4	O43511-1.1	V577S	Pathogenic	0.926
SLC26A4	O43511-1.1	V577T	Pathogenic	0.896
SLC26A4	O43511-1.1	V577W	Pathogenic	0.895
SLC26A4	O43511-1.1	V577Y	Pathogenic	0.885
SLC26A4	O43511-1.1	Y578A	Pathogenic	0.823
SLC26A4	O43511-1.1	Y578C	Pathogenic	0.933
SLC26A4	O43511-1.1	Y578D	Pathogenic	0.948
SLC26A4	O43511-1.1	Y578E	Pathogenic	0.956
SLC26A4	O43511-1.1	Y578F	Pathogenic	0.741
SLC26A4	O43511-1.1	Y578G	Pathogenic	0.779
SLC26A4	O43511-1.1	Y578H	Pathogenic	0.727
SLC26A4	O43511-1.1	Y578I	Pathogenic	0.966
SLC26A4	O43511-1.1	Y578K	Pathogenic	0.984
SLC26A4	O43511-1.1	Y578L	Pathogenic	0.967
SLC26A4	O43511-1.1	Y578M	Pathogenic	0.972
SLC26A4	O43511-1.1	Y578N	Pathogenic	0.924
SLC26A4	O43511-1.1	Y578P	Pathogenic	0.969
SLC26A4	O43511-1.1	Y578Q	Pathogenic	0.94
SLC26A4	O43511-1.1	Y578R	Pathogenic	0.983
SLC26A4	O43511-1.1	Y578S	Pathogenic	0.842
SLC26A4	O43511-1.1	Y578T	Pathogenic	0.936
SLC26A4	O43511-1.1	Y578V	Pathogenic	0.937
SLC26A4	O43511-1.1	Y578W	Pathogenic	0.7
SLC26A4	O43511-1.1	N579A	Pathogenic	0.927
SLC26A4	O43511-1.1	N579C	Pathogenic	0.979
SLC26A4	O43511-1.1	N579D	Pathogenic	0.86
SLC26A4	O43511-1.1	N579E	Pathogenic	0.901
SLC26A4	O43511-1.1	N579F	Pathogenic	0.902
SLC26A4	O43511-1.1	N579G	Pathogenic	0.601
SLC26A4	O43511-1.1	N579H	Pathogenic	0.697
SLC26A4	O43511-1.1	N579I	Pathogenic	0.938
SLC26A4	O43511-1.1	N579K	Pathogenic	0.71
SLC26A4	O43511-1.1	N579L	Pathogenic	0.94
SLC26A4	O43511-1.1	N579M	Pathogenic	0.903
SLC26A4	O43511-1.1	N579P	Pathogenic	0.968
SLC26A4	O43511-1.1	N579Q	Pathogenic	0.864
SLC26A4	O43511-1.1	N579R	Pathogenic	0.576
SLC26A4	O43511-1.1	N579S	Pathogenic	0.701
SLC26A4	O43511-1.1	N579T	Pathogenic	0.912
SLC26A4	O43511-1.1	N579V	Pathogenic	0.978
SLC26A4	O43511-1.1	N579W	Pathogenic	0.814
SLC26A4	O43511-1.1	N579Y	Pathogenic	0.828
SLC26A4	O43511-1.1	K580A	Pathogenic	0.934
SLC26A4	O43511-1.1	K580C	Pathogenic	0.991
SLC26A4	O43511-1.1	K580D	Pathogenic	0.985
SLC26A4	O43511-1.1	K580E	Pathogenic	0.971
SLC26A4	O43511-1.1	K580F	Pathogenic	0.999
SLC26A4	O43511-1.1	K580G	Pathogenic	0.932
SLC26A4	O43511-1.1	K580H	Pathogenic	0.993
SLC26A4	O43511-1.1	K580I	Pathogenic	0.998
SLC26A4	O43511-1.1	K580L	Pathogenic	0.995
SLC26A4	O43511-1.1	K580M	Pathogenic	0.992
SLC26A4	O43511-1.1	K580N	Pathogenic	0.974
SLC26A4	O43511-1.1	K580P	Pathogenic	0.972
SLC26A4	O43511-1.1	K580Q	Pathogenic	0.973
SLC26A4	O43511-1.1	K580R	Pathogenic	0.972
SLC26A4	O43511-1.1	K580S	Pathogenic	0.914
SLC26A4	O43511-1.1	K580T	Pathogenic	0.979
SLC26A4	O43511-1.1	K580V	Pathogenic	0.991
SLC26A4	O43511-1.1	K580W	Pathogenic	0.994
SLC26A4	O43511-1.1	K580Y	Pathogenic	0.997
SLC26A4	O43511-1.1	R581A	Pathogenic	0.974
SLC26A4	O43511-1.1	R581C	Pathogenic	0.996
SLC26A4	O43511-1.1	R581D	Pathogenic	0.997
SLC26A4	O43511-1.1	R581E	Pathogenic	0.994
SLC26A4	O43511-1.1	R581F	Pathogenic	0.999
SLC26A4	O43511-1.1	R581G	Pathogenic	0.973
SLC26A4	O43511-1.1	R581H	Pathogenic	0.995
SLC26A4	O43511-1.1	R581I	Pathogenic	0.999
SLC26A4	O43511-1.1	R581K	Pathogenic	0.994
SLC26A4	O43511-1.1	R581L	Pathogenic	0.998
SLC26A4	O43511-1.1	R581M	Pathogenic	0.997
SLC26A4	O43511-1.1	R581N	Pathogenic	0.99
SLC26A4	O43511-1.1	R581P	Pathogenic	0.994
SLC26A4	O43511-1.1	R581Q	Pathogenic	0.989
SLC26A4	O43511-1.1	R581S	Pathogenic	0.982
SLC26A4	O43511-1.1	R581T	Pathogenic	0.992
SLC26A4	O43511-1.1	R581V	Pathogenic	0.998
SLC26A4	O43511-1.1	R581W	Pathogenic	0.999
SLC26A4	O43511-1.1	R581Y	Pathogenic	0.999
SLC26A4	O43511-1.1	L582A	Neutral	0.118
SLC26A4	O43511-1.1	L582C	Neutral	0.291
SLC26A4	O43511-1.1	L582D	Pathogenic	0.679
SLC26A4	O43511-1.1	L582E	Pathogenic	0.714
SLC26A4	O43511-1.1	L582F	Neutral	0.468
SLC26A4	O43511-1.1	L582G	Neutral	0.29
SLC26A4	O43511-1.1	L582H	Pathogenic	0.835
SLC26A4	O43511-1.1	L582I	Neutral	0.262
SLC26A4	O43511-1.1	L582K	Pathogenic	0.565
SLC26A4	O43511-1.1	L582M	Neutral	0.236
SLC26A4	O43511-1.1	L582N	Pathogenic	0.585
SLC26A4	O43511-1.1	L582P	Pathogenic	0.641
SLC26A4	O43511-1.1	L582Q	Pathogenic	0.647
SLC26A4	O43511-1.1	L582R	Neutral	0.418
SLC26A4	O43511-1.1	L582S	Neutral	0.236
SLC26A4	O43511-1.1	L582T	Neutral	0.298
SLC26A4	O43511-1.1	L582V	Neutral	0.208
SLC26A4	O43511-1.1	L582W	Neutral	0.456
SLC26A4	O43511-1.1	L582Y	Pathogenic	0.512
SLC26A4	O43511-1.1	K583A	Pathogenic	0.96
SLC26A4	O43511-1.1	K583C	Pathogenic	0.994
SLC26A4	O43511-1.1	K583D	Pathogenic	0.991
SLC26A4	O43511-1.1	K583E	Pathogenic	0.983
SLC26A4	O43511-1.1	K583F	Pathogenic	0.999
SLC26A4	O43511-1.1	K583G	Pathogenic	0.958
SLC26A4	O43511-1.1	K583H	Pathogenic	0.996
SLC26A4	O43511-1.1	K583I	Pathogenic	0.999
SLC26A4	O43511-1.1	K583L	Pathogenic	0.997
SLC26A4	O43511-1.1	K583M	Pathogenic	0.995
SLC26A4	O43511-1.1	K583N	Pathogenic	0.984
SLC26A4	O43511-1.1	K583P	Pathogenic	0.983
SLC26A4	O43511-1.1	K583Q	Pathogenic	0.984
SLC26A4	O43511-1.1	K583R	Pathogenic	0.983
SLC26A4	O43511-1.1	K583S	Pathogenic	0.947
SLC26A4	O43511-1.1	K583T	Pathogenic	0.988
SLC26A4	O43511-1.1	K583V	Pathogenic	0.995
SLC26A4	O43511-1.1	K583W	Pathogenic	0.996
SLC26A4	O43511-1.1	K583Y	Pathogenic	0.998
SLC26A4	O43511-1.1	A584C	Pathogenic	0.992
SLC26A4	O43511-1.1	A584D	Pathogenic	0.997
SLC26A4	O43511-1.1	A584E	Pathogenic	0.988
SLC26A4	O43511-1.1	A584F	Pathogenic	0.976
SLC26A4	O43511-1.1	A584G	Pathogenic	0.993
SLC26A4	O43511-1.1	A584H	Pathogenic	0.993
SLC26A4	O43511-1.1	A584I	Pathogenic	0.97
SLC26A4	O43511-1.1	A584K	Pathogenic	0.956
SLC26A4	O43511-1.1	A584L	Pathogenic	0.971
SLC26A4	O43511-1.1	A584M	Pathogenic	0.976
SLC26A4	O43511-1.1	A584N	Pathogenic	0.997
SLC26A4	O43511-1.1	A584P	Pathogenic	0.996
SLC26A4	O43511-1.1	A584Q	Pathogenic	0.987
SLC26A4	O43511-1.1	A584R	Pathogenic	0.922
SLC26A4	O43511-1.1	A584S	Pathogenic	0.992
SLC26A4	O43511-1.1	A584T	Pathogenic	0.991
SLC26A4	O43511-1.1	A584V	Pathogenic	0.98
SLC26A4	O43511-1.1	A584W	Pathogenic	0.95
SLC26A4	O43511-1.1	A584Y	Pathogenic	0.977
SLC26A4	O43511-1.1	L585A	Pathogenic	0.834
SLC26A4	O43511-1.1	L585C	Pathogenic	0.939
SLC26A4	O43511-1.1	L585D	Pathogenic	0.988
SLC26A4	O43511-1.1	L585E	Pathogenic	0.989
SLC26A4	O43511-1.1	L585F	Pathogenic	0.971
SLC26A4	O43511-1.1	L585G	Pathogenic	0.939
SLC26A4	O43511-1.1	L585H	Pathogenic	0.995
SLC26A4	O43511-1.1	L585I	Pathogenic	0.93
SLC26A4	O43511-1.1	L585K	Pathogenic	0.98
SLC26A4	O43511-1.1	L585M	Pathogenic	0.921
SLC26A4	O43511-1.1	L585N	Pathogenic	0.981
SLC26A4	O43511-1.1	L585P	Pathogenic	0.985
SLC26A4	O43511-1.1	L585Q	Pathogenic	0.986
SLC26A4	O43511-1.1	L585R	Pathogenic	0.964
SLC26A4	O43511-1.1	L585S	Pathogenic	0.921
SLC26A4	O43511-1.1	L585T	Pathogenic	0.941
SLC26A4	O43511-1.1	L585V	Pathogenic	0.908
SLC26A4	O43511-1.1	L585W	Pathogenic	0.969
SLC26A4	O43511-1.1	L585Y	Pathogenic	0.975
SLC26A4	O43511-1.1	R586A	Pathogenic	0.794
SLC26A4	O43511-1.1	R586C	Pathogenic	0.966
SLC26A4	O43511-1.1	R586D	Pathogenic	0.972
SLC26A4	O43511-1.1	R586E	Pathogenic	0.948
SLC26A4	O43511-1.1	R586F	Pathogenic	0.995
SLC26A4	O43511-1.1	R586G	Pathogenic	0.787
SLC26A4	O43511-1.1	R586H	Pathogenic	0.954
SLC26A4	O43511-1.1	R586I	Pathogenic	0.991
SLC26A4	O43511-1.1	R586K	Pathogenic	0.944
SLC26A4	O43511-1.1	R586L	Pathogenic	0.983
SLC26A4	O43511-1.1	R586M	Pathogenic	0.973
SLC26A4	O43511-1.1	R586N	Pathogenic	0.91
SLC26A4	O43511-1.1	R586P	Pathogenic	0.949
SLC26A4	O43511-1.1	R586Q	Pathogenic	0.907
SLC26A4	O43511-1.1	R586S	Pathogenic	0.852
SLC26A4	O43511-1.1	R586T	Pathogenic	0.927
SLC26A4	O43511-1.1	R586V	Pathogenic	0.984
SLC26A4	O43511-1.1	R586W	Pathogenic	0.993
SLC26A4	O43511-1.1	R586Y	Pathogenic	0.994
SLC26A4	O43511-1.1	K587A	Pathogenic	0.728
SLC26A4	O43511-1.1	K587C	Pathogenic	0.951
SLC26A4	O43511-1.1	K587D	Pathogenic	0.923
SLC26A4	O43511-1.1	K587E	Pathogenic	0.864
SLC26A4	O43511-1.1	K587F	Pathogenic	0.992
SLC26A4	O43511-1.1	K587G	Pathogenic	0.719
SLC26A4	O43511-1.1	K587H	Pathogenic	0.966
SLC26A4	O43511-1.1	K587I	Pathogenic	0.988
SLC26A4	O43511-1.1	K587L	Pathogenic	0.976
SLC26A4	O43511-1.1	K587M	Pathogenic	0.961
SLC26A4	O43511-1.1	K587N	Pathogenic	0.875
SLC26A4	O43511-1.1	K587P	Pathogenic	0.866
SLC26A4	O43511-1.1	K587Q	Pathogenic	0.871
SLC26A4	O43511-1.1	K587R	Pathogenic	0.866
SLC26A4	O43511-1.1	K587S	Pathogenic	0.666
SLC26A4	O43511-1.1	K587T	Pathogenic	0.898
SLC26A4	O43511-1.1	K587V	Pathogenic	0.955
SLC26A4	O43511-1.1	K587W	Pathogenic	0.969
SLC26A4	O43511-1.1	K587Y	Pathogenic	0.986
SLC26A4	O43511-1.1	I588A	Pathogenic	0.806
SLC26A4	O43511-1.1	I588C	Pathogenic	0.927
SLC26A4	O43511-1.1	I588D	Pathogenic	0.97
SLC26A4	O43511-1.1	I588E	Pathogenic	0.987
SLC26A4	O43511-1.1	I588F	Pathogenic	0.967
SLC26A4	O43511-1.1	I588G	Pathogenic	0.927
SLC26A4	O43511-1.1	I588H	Pathogenic	0.994
SLC26A4	O43511-1.1	I588K	Pathogenic	0.988
SLC26A4	O43511-1.1	I588L	Pathogenic	0.92
SLC26A4	O43511-1.1	I588M	Pathogenic	0.951
SLC26A4	O43511-1.1	I588N	Pathogenic	0.978
SLC26A4	O43511-1.1	I588P	Pathogenic	0.982
SLC26A4	O43511-1.1	I588Q	Pathogenic	0.991
SLC26A4	O43511-1.1	I588R	Pathogenic	0.978
SLC26A4	O43511-1.1	I588S	Pathogenic	0.906
SLC26A4	O43511-1.1	I588T	Pathogenic	0.93
SLC26A4	O43511-1.1	I588V	Pathogenic	0.668
SLC26A4	O43511-1.1	I588W	Pathogenic	0.983
SLC26A4	O43511-1.1	I588Y	Pathogenic	0.97
SLC26A4	O43511-1.1	Q589A	Pathogenic	0.772
SLC26A4	O43511-1.1	Q589C	Pathogenic	0.961
SLC26A4	O43511-1.1	Q589D	Pathogenic	0.831
SLC26A4	O43511-1.1	Q589E	Pathogenic	0.743
SLC26A4	O43511-1.1	Q589F	Pathogenic	0.961
SLC26A4	O43511-1.1	Q589G	Pathogenic	0.764
SLC26A4	O43511-1.1	Q589H	Pathogenic	0.926
SLC26A4	O43511-1.1	Q589I	Pathogenic	0.976
SLC26A4	O43511-1.1	Q589K	Pathogenic	0.712
SLC26A4	O43511-1.1	Q589L	Pathogenic	0.955
SLC26A4	O43511-1.1	Q589M	Pathogenic	0.862
SLC26A4	O43511-1.1	Q589N	Pathogenic	0.868
SLC26A4	O43511-1.1	Q589P	Pathogenic	0.891
SLC26A4	O43511-1.1	Q589R	Pathogenic	0.577
SLC26A4	O43511-1.1	Q589S	Pathogenic	0.716
SLC26A4	O43511-1.1	Q589T	Pathogenic	0.918
SLC26A4	O43511-1.1	Q589V	Pathogenic	0.964
SLC26A4	O43511-1.1	Q589W	Pathogenic	0.746
SLC26A4	O43511-1.1	Q589Y	Pathogenic	0.866
SLC26A4	O43511-1.1	K590A	Pathogenic	0.927
SLC26A4	O43511-1.1	K590C	Pathogenic	0.989
SLC26A4	O43511-1.1	K590D	Pathogenic	0.983
SLC26A4	O43511-1.1	K590E	Pathogenic	0.968
SLC26A4	O43511-1.1	K590F	Pathogenic	0.998
SLC26A4	O43511-1.1	K590G	Pathogenic	0.924
SLC26A4	O43511-1.1	K590H	Pathogenic	0.993
SLC26A4	O43511-1.1	K590I	Pathogenic	0.997
SLC26A4	O43511-1.1	K590L	Pathogenic	0.995
SLC26A4	O43511-1.1	K590M	Pathogenic	0.991
SLC26A4	O43511-1.1	K590N	Pathogenic	0.971
SLC26A4	O43511-1.1	K590P	Pathogenic	0.968
SLC26A4	O43511-1.1	K590Q	Pathogenic	0.97
SLC26A4	O43511-1.1	K590R	Pathogenic	0.968
SLC26A4	O43511-1.1	K590S	Pathogenic	0.904
SLC26A4	O43511-1.1	K590T	Pathogenic	0.977
SLC26A4	O43511-1.1	K590V	Pathogenic	0.99
SLC26A4	O43511-1.1	K590W	Pathogenic	0.993
SLC26A4	O43511-1.1	K590Y	Pathogenic	0.997
SLC26A4	O43511-1.1	L591A	Pathogenic	0.539
SLC26A4	O43511-1.1	L591C	Pathogenic	0.782
SLC26A4	O43511-1.1	L591D	Pathogenic	0.949
SLC26A4	O43511-1.1	L591E	Pathogenic	0.956
SLC26A4	O43511-1.1	L591F	Pathogenic	0.885
SLC26A4	O43511-1.1	L591G	Pathogenic	0.782
SLC26A4	O43511-1.1	L591H	Pathogenic	0.978
SLC26A4	O43511-1.1	L591I	Pathogenic	0.757
SLC26A4	O43511-1.1	L591K	Pathogenic	0.919
SLC26A4	O43511-1.1	L591M	Pathogenic	0.73
SLC26A4	O43511-1.1	L591N	Pathogenic	0.925
SLC26A4	O43511-1.1	L591P	Pathogenic	0.94
SLC26A4	O43511-1.1	L591Q	Pathogenic	0.941
SLC26A4	O43511-1.1	L591R	Pathogenic	0.863
SLC26A4	O43511-1.1	L591S	Pathogenic	0.73
SLC26A4	O43511-1.1	L591T	Pathogenic	0.788
SLC26A4	O43511-1.1	L591V	Pathogenic	0.696
SLC26A4	O43511-1.1	L591W	Pathogenic	0.88
SLC26A4	O43511-1.1	L591Y	Pathogenic	0.902
SLC26A4	O43511-1.1	I592A	Neutral	0.208
SLC26A4	O43511-1.1	I592C	Neutral	0.446
SLC26A4	O43511-1.1	I592D	Pathogenic	0.674
SLC26A4	O43511-1.1	I592E	Pathogenic	0.831
SLC26A4	O43511-1.1	I592F	Pathogenic	0.649
SLC26A4	O43511-1.1	I592G	Neutral	0.445
SLC26A4	O43511-1.1	I592H	Pathogenic	0.908
SLC26A4	O43511-1.1	I592K	Pathogenic	0.837
SLC26A4	O43511-1.1	I592L	Neutral	0.421
SLC26A4	O43511-1.1	I592M	Pathogenic	0.549
SLC26A4	O43511-1.1	I592N	Pathogenic	0.734
SLC26A4	O43511-1.1	I592P	Pathogenic	0.778
SLC26A4	O43511-1.1	I592Q	Pathogenic	0.878
SLC26A4	O43511-1.1	I592R	Pathogenic	0.739
SLC26A4	O43511-1.1	I592S	Neutral	0.377
SLC26A4	O43511-1.1	I592T	Neutral	0.454
SLC26A4	O43511-1.1	I592V	Neutral	0.113
SLC26A4	O43511-1.1	I592W	Pathogenic	0.782
SLC26A4	O43511-1.1	I592Y	Pathogenic	0.673
SLC26A4	O43511-1.1	K593A	Pathogenic	0.903
SLC26A4	O43511-1.1	K593C	Pathogenic	0.986
SLC26A4	O43511-1.1	K593D	Pathogenic	0.977
SLC26A4	O43511-1.1	K593E	Pathogenic	0.957
SLC26A4	O43511-1.1	K593F	Pathogenic	0.998
SLC26A4	O43511-1.1	K593G	Pathogenic	0.9
SLC26A4	O43511-1.1	K593H	Pathogenic	0.99
SLC26A4	O43511-1.1	K593I	Pathogenic	0.996
SLC26A4	O43511-1.1	K593L	Pathogenic	0.993
SLC26A4	O43511-1.1	K593M	Pathogenic	0.988
SLC26A4	O43511-1.1	K593N	Pathogenic	0.961
SLC26A4	O43511-1.1	K593P	Pathogenic	0.957
SLC26A4	O43511-1.1	K593Q	Pathogenic	0.959
SLC26A4	O43511-1.1	K593R	Pathogenic	0.958
SLC26A4	O43511-1.1	K593S	Pathogenic	0.874
SLC26A4	O43511-1.1	K593T	Pathogenic	0.969
SLC26A4	O43511-1.1	K593V	Pathogenic	0.987
SLC26A4	O43511-1.1	K593W	Pathogenic	0.991
SLC26A4	O43511-1.1	K593Y	Pathogenic	0.996
SLC26A4	O43511-1.1	S594A	Neutral	0.005
SLC26A4	O43511-1.1	S594C	Neutral	0.011
SLC26A4	O43511-1.1	S594D	Neutral	0.005
SLC26A4	O43511-1.1	S594E	Neutral	0.002
SLC26A4	O43511-1.1	S594F	Neutral	0.002
SLC26A4	O43511-1.1	S594G	Neutral	0.005
SLC26A4	O43511-1.1	S594H	Neutral	0.004
SLC26A4	O43511-1.1	S594I	Neutral	0.003
SLC26A4	O43511-1.1	S594K	Neutral	0.001
SLC26A4	O43511-1.1	S594L	Neutral	0.003
SLC26A4	O43511-1.1	S594M	Neutral	0.002
SLC26A4	O43511-1.1	S594N	Neutral	0.002
SLC26A4	O43511-1.1	S594P	Neutral	0.01
SLC26A4	O43511-1.1	S594Q	Neutral	0.002
SLC26A4	O43511-1.1	S594R	Neutral	0.001
SLC26A4	O43511-1.1	S594T	Neutral	0.003
SLC26A4	O43511-1.1	S594V	Neutral	0.009
SLC26A4	O43511-1.1	S594W	Neutral	0.001
SLC26A4	O43511-1.1	S594Y	Neutral	0.002
SLC26A4	O43511-1.1	G595A	Pathogenic	0.986
SLC26A4	O43511-1.1	G595C	Pathogenic	0.995
SLC26A4	O43511-1.1	G595D	Pathogenic	0.975
SLC26A4	O43511-1.1	G595E	Pathogenic	0.974
SLC26A4	O43511-1.1	G595F	Pathogenic	0.936
SLC26A4	O43511-1.1	G595H	Pathogenic	0.968
SLC26A4	O43511-1.1	G595I	Pathogenic	0.98
SLC26A4	O43511-1.1	G595K	Pathogenic	0.909
SLC26A4	O43511-1.1	G595L	Pathogenic	0.98
SLC26A4	O43511-1.1	G595M	Pathogenic	0.968
SLC26A4	O43511-1.1	G595N	Pathogenic	0.943
SLC26A4	O43511-1.1	G595P	Pathogenic	0.988
SLC26A4	O43511-1.1	G595Q	Pathogenic	0.972
SLC26A4	O43511-1.1	G595R	Pathogenic	0.846
SLC26A4	O43511-1.1	G595S	Pathogenic	0.983
SLC26A4	O43511-1.1	G595T	Pathogenic	0.989
SLC26A4	O43511-1.1	G595V	Pathogenic	0.986
SLC26A4	O43511-1.1	G595W	Pathogenic	0.633
SLC26A4	O43511-1.1	G595Y	Pathogenic	0.939
SLC26A4	O43511-1.1	Q596A	Neutral	0.338
SLC26A4	O43511-1.1	Q596C	Pathogenic	0.789
SLC26A4	O43511-1.1	Q596D	Neutral	0.427
SLC26A4	O43511-1.1	Q596E	Neutral	0.304
SLC26A4	O43511-1.1	Q596F	Pathogenic	0.79
SLC26A4	O43511-1.1	Q596G	Neutral	0.329
SLC26A4	O43511-1.1	Q596H	Pathogenic	0.654
SLC26A4	O43511-1.1	Q596I	Pathogenic	0.86
SLC26A4	O43511-1.1	Q596K	Neutral	0.271
SLC26A4	O43511-1.1	Q596L	Pathogenic	0.761
SLC26A4	O43511-1.1	Q596M	Neutral	0.486
SLC26A4	O43511-1.1	Q596N	Neutral	0.499
SLC26A4	O43511-1.1	Q596P	Pathogenic	0.552
SLC26A4	O43511-1.1	Q596R	Neutral	0.171
SLC26A4	O43511-1.1	Q596S	Neutral	0.276
SLC26A4	O43511-1.1	Q596T	Pathogenic	0.627
SLC26A4	O43511-1.1	Q596V	Pathogenic	0.801
SLC26A4	O43511-1.1	Q596W	Neutral	0.307
SLC26A4	O43511-1.1	Q596Y	Neutral	0.495
SLC26A4	O43511-1.1	L597A	Pathogenic	0.871
SLC26A4	O43511-1.1	L597C	Pathogenic	0.954
SLC26A4	O43511-1.1	L597D	Pathogenic	0.991
SLC26A4	O43511-1.1	L597E	Pathogenic	0.992
SLC26A4	O43511-1.1	L597F	Pathogenic	0.978
SLC26A4	O43511-1.1	L597G	Pathogenic	0.954
SLC26A4	O43511-1.1	L597H	Pathogenic	0.996
SLC26A4	O43511-1.1	L597I	Pathogenic	0.947
SLC26A4	O43511-1.1	L597K	Pathogenic	0.985
SLC26A4	O43511-1.1	L597M	Pathogenic	0.94
SLC26A4	O43511-1.1	L597N	Pathogenic	0.986
SLC26A4	O43511-1.1	L597P	Pathogenic	0.989
SLC26A4	O43511-1.1	L597Q	Pathogenic	0.989
SLC26A4	O43511-1.1	L597R	Pathogenic	0.973
SLC26A4	O43511-1.1	L597S	Pathogenic	0.94
SLC26A4	O43511-1.1	L597T	Pathogenic	0.955
SLC26A4	O43511-1.1	L597V	Pathogenic	0.93
SLC26A4	O43511-1.1	L597W	Pathogenic	0.977
SLC26A4	O43511-1.1	L597Y	Pathogenic	0.981
SLC26A4	O43511-1.1	R598A	Neutral	0.176
SLC26A4	O43511-1.1	R598C	Pathogenic	0.611
SLC26A4	O43511-1.1	R598D	Pathogenic	0.658
SLC26A4	O43511-1.1	R598E	Pathogenic	0.505
SLC26A4	O43511-1.1	R598F	Pathogenic	0.913
SLC26A4	O43511-1.1	R598G	Neutral	0.17
SLC26A4	O43511-1.1	R598H	Pathogenic	0.533
SLC26A4	O43511-1.1	R598I	Pathogenic	0.864
SLC26A4	O43511-1.1	R598K	Neutral	0.484
SLC26A4	O43511-1.1	R598L	Pathogenic	0.767
SLC26A4	O43511-1.1	R598M	Pathogenic	0.663
SLC26A4	O43511-1.1	R598N	Neutral	0.359
SLC26A4	O43511-1.1	R598P	Pathogenic	0.509
SLC26A4	O43511-1.1	R598Q	Neutral	0.352
SLC26A4	O43511-1.1	R598S	Neutral	0.243
SLC26A4	O43511-1.1	R598T	Neutral	0.414
SLC26A4	O43511-1.1	R598V	Pathogenic	0.772
SLC26A4	O43511-1.1	R598W	Pathogenic	0.889
SLC26A4	O43511-1.1	R598Y	Pathogenic	0.904
SLC26A4	O43511-1.1	A599C	Neutral	0.307
SLC26A4	O43511-1.1	A599D	Pathogenic	0.55
SLC26A4	O43511-1.1	A599E	Neutral	0.221
SLC26A4	O43511-1.1	A599F	Neutral	0.125
SLC26A4	O43511-1.1	A599G	Neutral	0.338
SLC26A4	O43511-1.1	A599H	Neutral	0.338
SLC26A4	O43511-1.1	A599I	Neutral	0.104
SLC26A4	O43511-1.1	A599K	Neutral	0.071
SLC26A4	O43511-1.1	A599L	Neutral	0.108
SLC26A4	O43511-1.1	A599M	Neutral	0.127
SLC26A4	O43511-1.1	A599N	Pathogenic	0.51
SLC26A4	O43511-1.1	A599P	Neutral	0.451
SLC26A4	O43511-1.1	A599Q	Neutral	0.21
SLC26A4	O43511-1.1	A599R	Neutral	0.041
SLC26A4	O43511-1.1	A599S	Neutral	0.31
SLC26A4	O43511-1.1	A599T	Neutral	0.291
SLC26A4	O43511-1.1	A599V	Neutral	0.146
SLC26A4	O43511-1.1	A599W	Neutral	0.064
SLC26A4	O43511-1.1	A599Y	Neutral	0.131
SLC26A4	O43511-1.1	T600A	Pathogenic	0.988
SLC26A4	O43511-1.1	T600C	Pathogenic	0.997
SLC26A4	O43511-1.1	T600D	Pathogenic	0.997
SLC26A4	O43511-1.1	T600E	Pathogenic	0.995
SLC26A4	O43511-1.1	T600F	Pathogenic	0.99
SLC26A4	O43511-1.1	T600G	Pathogenic	0.993
SLC26A4	O43511-1.1	T600H	Pathogenic	0.997
SLC26A4	O43511-1.1	T600I	Pathogenic	0.987
SLC26A4	O43511-1.1	T600K	Pathogenic	0.981
SLC26A4	O43511-1.1	T600L	Pathogenic	0.988
SLC26A4	O43511-1.1	T600M	Pathogenic	0.99
SLC26A4	O43511-1.1	T600N	Pathogenic	0.994
SLC26A4	O43511-1.1	T600P	Pathogenic	0.998
SLC26A4	O43511-1.1	T600Q	Pathogenic	0.995
SLC26A4	O43511-1.1	T600R	Pathogenic	0.967
SLC26A4	O43511-1.1	T600S	Pathogenic	0.981
SLC26A4	O43511-1.1	T600V	Pathogenic	0.991
SLC26A4	O43511-1.1	T600W	Pathogenic	0.957
SLC26A4	O43511-1.1	T600Y	Pathogenic	0.99
SLC26A4	O43511-1.1	K601A	Neutral	0.142
SLC26A4	O43511-1.1	K601C	Pathogenic	0.548
SLC26A4	O43511-1.1	K601D	Neutral	0.425
SLC26A4	O43511-1.1	K601E	Neutral	0.282
SLC26A4	O43511-1.1	K601F	Pathogenic	0.89
SLC26A4	O43511-1.1	K601G	Neutral	0.137
SLC26A4	O43511-1.1	K601H	Pathogenic	0.639
SLC26A4	O43511-1.1	K601I	Pathogenic	0.831
SLC26A4	O43511-1.1	K601L	Pathogenic	0.718
SLC26A4	O43511-1.1	K601M	Pathogenic	0.603
SLC26A4	O43511-1.1	K601N	Neutral	0.302
SLC26A4	O43511-1.1	K601P	Neutral	0.285
SLC26A4	O43511-1.1	K601Q	Neutral	0.295
SLC26A4	O43511-1.1	K601R	Neutral	0.286
SLC26A4	O43511-1.1	K601S	Neutral	0.11
SLC26A4	O43511-1.1	K601T	Neutral	0.353
SLC26A4	O43511-1.1	K601V	Pathogenic	0.565
SLC26A4	O43511-1.1	K601W	Pathogenic	0.658
SLC26A4	O43511-1.1	K601Y	Pathogenic	0.809
SLC26A4	O43511-1.1	N602A	Pathogenic	0.884
SLC26A4	O43511-1.1	N602C	Pathogenic	0.965
SLC26A4	O43511-1.1	N602D	Pathogenic	0.788
SLC26A4	O43511-1.1	N602E	Pathogenic	0.845
SLC26A4	O43511-1.1	N602F	Pathogenic	0.847
SLC26A4	O43511-1.1	N602G	Neutral	0.475
SLC26A4	O43511-1.1	N602H	Pathogenic	0.581
SLC26A4	O43511-1.1	N602I	Pathogenic	0.9
SLC26A4	O43511-1.1	N602K	Pathogenic	0.596
SLC26A4	O43511-1.1	N602L	Pathogenic	0.904
SLC26A4	O43511-1.1	N602M	Pathogenic	0.849
SLC26A4	O43511-1.1	N602P	Pathogenic	0.949
SLC26A4	O43511-1.1	N602Q	Pathogenic	0.792
SLC26A4	O43511-1.1	N602R	Neutral	0.449
SLC26A4	O43511-1.1	N602S	Pathogenic	0.586
SLC26A4	O43511-1.1	N602T	Pathogenic	0.862
SLC26A4	O43511-1.1	N602V	Pathogenic	0.964
SLC26A4	O43511-1.1	N602W	Pathogenic	0.724
SLC26A4	O43511-1.1	N602Y	Pathogenic	0.743
SLC26A4	O43511-1.1	G603A	Pathogenic	0.962
SLC26A4	O43511-1.1	G603C	Pathogenic	0.986
SLC26A4	O43511-1.1	G603D	Pathogenic	0.936
SLC26A4	O43511-1.1	G603E	Pathogenic	0.932
SLC26A4	O43511-1.1	G603F	Pathogenic	0.845
SLC26A4	O43511-1.1	G603H	Pathogenic	0.917
SLC26A4	O43511-1.1	G603I	Pathogenic	0.947
SLC26A4	O43511-1.1	G603K	Pathogenic	0.787
SLC26A4	O43511-1.1	G603L	Pathogenic	0.949
SLC26A4	O43511-1.1	G603M	Pathogenic	0.917
SLC26A4	O43511-1.1	G603N	Pathogenic	0.861
SLC26A4	O43511-1.1	G603P	Pathogenic	0.969
SLC26A4	O43511-1.1	G603Q	Pathogenic	0.928
SLC26A4	O43511-1.1	G603R	Pathogenic	0.672
SLC26A4	O43511-1.1	G603S	Pathogenic	0.956
SLC26A4	O43511-1.1	G603T	Pathogenic	0.97
SLC26A4	O43511-1.1	G603V	Pathogenic	0.963
SLC26A4	O43511-1.1	G603W	Neutral	0.391
SLC26A4	O43511-1.1	G603Y	Pathogenic	0.851
SLC26A4	O43511-1.1	I604A	Neutral	0.061
SLC26A4	O43511-1.1	I604C	Neutral	0.167
SLC26A4	O43511-1.1	I604D	Neutral	0.34
SLC26A4	O43511-1.1	I604E	Pathogenic	0.55
SLC26A4	O43511-1.1	I604F	Neutral	0.315
SLC26A4	O43511-1.1	I604G	Neutral	0.166
SLC26A4	O43511-1.1	I604H	Pathogenic	0.711
SLC26A4	O43511-1.1	I604K	Pathogenic	0.561
SLC26A4	O43511-1.1	I604L	Neutral	0.153
SLC26A4	O43511-1.1	I604M	Neutral	0.233
SLC26A4	O43511-1.1	I604N	Neutral	0.408
SLC26A4	O43511-1.1	I604P	Neutral	0.466
SLC26A4	O43511-1.1	I604Q	Pathogenic	0.642
SLC26A4	O43511-1.1	I604R	Neutral	0.414
SLC26A4	O43511-1.1	I604S	Neutral	0.131
SLC26A4	O43511-1.1	I604T	Neutral	0.172
SLC26A4	O43511-1.1	I604V	Neutral	0.031
SLC26A4	O43511-1.1	I604W	Neutral	0.471
SLC26A4	O43511-1.1	I604Y	Neutral	0.338
SLC26A4	O43511-1.1	I605A	Pathogenic	0.572
SLC26A4	O43511-1.1	I605C	Pathogenic	0.804
SLC26A4	O43511-1.1	I605D	Pathogenic	0.913
SLC26A4	O43511-1.1	I605E	Pathogenic	0.961
SLC26A4	O43511-1.1	I605F	Pathogenic	0.904
SLC26A4	O43511-1.1	I605G	Pathogenic	0.803
SLC26A4	O43511-1.1	I605H	Pathogenic	0.981
SLC26A4	O43511-1.1	I605K	Pathogenic	0.963
SLC26A4	O43511-1.1	I605L	Pathogenic	0.787
SLC26A4	O43511-1.1	I605M	Pathogenic	0.861
SLC26A4	O43511-1.1	I605N	Pathogenic	0.934
SLC26A4	O43511-1.1	I605P	Pathogenic	0.947
SLC26A4	O43511-1.1	I605Q	Pathogenic	0.974
SLC26A4	O43511-1.1	I605R	Pathogenic	0.935
SLC26A4	O43511-1.1	I605S	Pathogenic	0.755
SLC26A4	O43511-1.1	I605T	Pathogenic	0.809
SLC26A4	O43511-1.1	I605V	Neutral	0.393
SLC26A4	O43511-1.1	I605W	Pathogenic	0.948
SLC26A4	O43511-1.1	I605Y	Pathogenic	0.913
SLC26A4	O43511-1.1	S606A	Neutral	0.214
SLC26A4	O43511-1.1	S606C	Neutral	0.381
SLC26A4	O43511-1.1	S606D	Neutral	0.215
SLC26A4	O43511-1.1	S606E	Neutral	0.113
SLC26A4	O43511-1.1	S606F	Neutral	0.09
SLC26A4	O43511-1.1	S606G	Neutral	0.207
SLC26A4	O43511-1.1	S606H	Neutral	0.168
SLC26A4	O43511-1.1	S606I	Neutral	0.14
SLC26A4	O43511-1.1	S606K	Neutral	0.033
SLC26A4	O43511-1.1	S606L	Neutral	0.145
SLC26A4	O43511-1.1	S606M	Neutral	0.092
SLC26A4	O43511-1.1	S606N	Neutral	0.104
SLC26A4	O43511-1.1	S606P	Neutral	0.363
SLC26A4	O43511-1.1	S606Q	Neutral	0.107
SLC26A4	O43511-1.1	S606R	Neutral	0.037
SLC26A4	O43511-1.1	S606T	Neutral	0.128
SLC26A4	O43511-1.1	S606V	Neutral	0.324
SLC26A4	O43511-1.1	S606W	Neutral	0.045
SLC26A4	O43511-1.1	S606Y	Neutral	0.094
SLC26A4	O43511-1.1	D607A	Neutral	0.39
SLC26A4	O43511-1.1	D607C	Pathogenic	0.701
SLC26A4	O43511-1.1	D607E	Neutral	0.069
SLC26A4	O43511-1.1	D607F	Neutral	0.228
SLC26A4	O43511-1.1	D607G	Neutral	0.132
SLC26A4	O43511-1.1	D607H	Neutral	0.23
SLC26A4	O43511-1.1	D607I	Neutral	0.325
SLC26A4	O43511-1.1	D607K	Neutral	0.152
SLC26A4	O43511-1.1	D607L	Pathogenic	0.502
SLC26A4	O43511-1.1	D607M	Neutral	0.375
SLC26A4	O43511-1.1	D607N	Neutral	0.209
SLC26A4	O43511-1.1	D607P	Neutral	0.435
SLC26A4	O43511-1.1	D607Q	Neutral	0.169
SLC26A4	O43511-1.1	D607R	Neutral	0.167
SLC26A4	O43511-1.1	D607S	Neutral	0.192
SLC26A4	O43511-1.1	D607T	Neutral	0.468
SLC26A4	O43511-1.1	D607V	Pathogenic	0.587
SLC26A4	O43511-1.1	D607W	Neutral	0.123
SLC26A4	O43511-1.1	D607Y	Neutral	0.236
SLC26A4	O43511-1.1	A608C	Neutral	0.239
SLC26A4	O43511-1.1	A608D	Neutral	0.463
SLC26A4	O43511-1.1	A608E	Neutral	0.167
SLC26A4	O43511-1.1	A608F	Neutral	0.092
SLC26A4	O43511-1.1	A608G	Neutral	0.265
SLC26A4	O43511-1.1	A608H	Neutral	0.265
SLC26A4	O43511-1.1	A608I	Neutral	0.076
SLC26A4	O43511-1.1	A608K	Neutral	0.051
SLC26A4	O43511-1.1	A608L	Neutral	0.079
SLC26A4	O43511-1.1	A608M	Neutral	0.093
SLC26A4	O43511-1.1	A608N	Neutral	0.424
SLC26A4	O43511-1.1	A608P	Neutral	0.368
SLC26A4	O43511-1.1	A608Q	Neutral	0.158
SLC26A4	O43511-1.1	A608R	Neutral	0.029
SLC26A4	O43511-1.1	A608S	Neutral	0.242
SLC26A4	O43511-1.1	A608T	Neutral	0.225
SLC26A4	O43511-1.1	A608V	Neutral	0.108
SLC26A4	O43511-1.1	A608W	Neutral	0.046
SLC26A4	O43511-1.1	A608Y	Neutral	0.096
SLC26A4	O43511-1.1	V609A	Neutral	0.0
SLC26A4	O43511-1.1	V609C	Neutral	0.0
SLC26A4	O43511-1.1	V609D	Neutral	0.0
SLC26A4	O43511-1.1	V609E	Neutral	0.0
SLC26A4	O43511-1.1	V609F	Neutral	0.0
SLC26A4	O43511-1.1	V609G	Neutral	0.0
SLC26A4	O43511-1.1	V609H	Neutral	0.0
SLC26A4	O43511-1.1	V609I	Neutral	0.0
SLC26A4	O43511-1.1	V609K	Neutral	0.0
SLC26A4	O43511-1.1	V609L	Neutral	0.0
SLC26A4	O43511-1.1	V609M	Neutral	0.0
SLC26A4	O43511-1.1	V609N	Neutral	0.0
SLC26A4	O43511-1.1	V609P	Neutral	0.0
SLC26A4	O43511-1.1	V609Q	Neutral	0.0
SLC26A4	O43511-1.1	V609R	Neutral	0.0
SLC26A4	O43511-1.1	V609S	Neutral	0.0
SLC26A4	O43511-1.1	V609T	Neutral	0.0
SLC26A4	O43511-1.1	V609W	Neutral	0.0
SLC26A4	O43511-1.1	V609Y	Neutral	0.0
SLC26A4	O43511-1.1	S610A	Neutral	0.034
SLC26A4	O43511-1.1	S610C	Neutral	0.075
SLC26A4	O43511-1.1	S610D	Neutral	0.035
SLC26A4	O43511-1.1	S610E	Neutral	0.016
SLC26A4	O43511-1.1	S610F	Neutral	0.013
SLC26A4	O43511-1.1	S610G	Neutral	0.033
SLC26A4	O43511-1.1	S610H	Neutral	0.026
SLC26A4	O43511-1.1	S610I	Neutral	0.021
SLC26A4	O43511-1.1	S610K	Neutral	0.004
SLC26A4	O43511-1.1	S610L	Neutral	0.022
SLC26A4	O43511-1.1	S610M	Neutral	0.013
SLC26A4	O43511-1.1	S610N	Neutral	0.015
SLC26A4	O43511-1.1	S610P	Neutral	0.069
SLC26A4	O43511-1.1	S610Q	Neutral	0.015
SLC26A4	O43511-1.1	S610R	Neutral	0.005
SLC26A4	O43511-1.1	S610T	Neutral	0.019
SLC26A4	O43511-1.1	S610V	Neutral	0.059
SLC26A4	O43511-1.1	S610W	Neutral	0.006
SLC26A4	O43511-1.1	S610Y	Neutral	0.013
SLC26A4	O43511-1.1	T611A	Neutral	0.036
SLC26A4	O43511-1.1	T611C	Neutral	0.12
SLC26A4	O43511-1.1	T611D	Neutral	0.132
SLC26A4	O43511-1.1	T611E	Neutral	0.078
SLC26A4	O43511-1.1	T611F	Neutral	0.04
SLC26A4	O43511-1.1	T611G	Neutral	0.056
SLC26A4	O43511-1.1	T611H	Neutral	0.133
SLC26A4	O43511-1.1	T611I	Neutral	0.032
SLC26A4	O43511-1.1	T611K	Neutral	0.022
SLC26A4	O43511-1.1	T611L	Neutral	0.034
SLC26A4	O43511-1.1	T611M	Neutral	0.04
SLC26A4	O43511-1.1	T611N	Neutral	0.072
SLC26A4	O43511-1.1	T611P	Neutral	0.153
SLC26A4	O43511-1.1	T611Q	Neutral	0.074
SLC26A4	O43511-1.1	T611R	Neutral	0.013
SLC26A4	O43511-1.1	T611S	Neutral	0.022
SLC26A4	O43511-1.1	T611V	Neutral	0.047
SLC26A4	O43511-1.1	T611W	Neutral	0.01
SLC26A4	O43511-1.1	T611Y	Neutral	0.042
SLC26A4	O43511-1.1	N612A	Pathogenic	0.636
SLC26A4	O43511-1.1	N612C	Pathogenic	0.865
SLC26A4	O43511-1.1	N612D	Neutral	0.459
SLC26A4	O43511-1.1	N612E	Pathogenic	0.556
SLC26A4	O43511-1.1	N612F	Pathogenic	0.559
SLC26A4	O43511-1.1	N612G	Neutral	0.172
SLC26A4	O43511-1.1	N612H	Neutral	0.241
SLC26A4	O43511-1.1	N612I	Pathogenic	0.674
SLC26A4	O43511-1.1	N612K	Neutral	0.252
SLC26A4	O43511-1.1	N612L	Pathogenic	0.683
SLC26A4	O43511-1.1	N612M	Pathogenic	0.562
SLC26A4	O43511-1.1	N612P	Pathogenic	0.808
SLC26A4	O43511-1.1	N612Q	Neutral	0.466
SLC26A4	O43511-1.1	N612R	Neutral	0.157
SLC26A4	O43511-1.1	N612S	Neutral	0.244
SLC26A4	O43511-1.1	N612T	Pathogenic	0.589
SLC26A4	O43511-1.1	N612V	Pathogenic	0.859
SLC26A4	O43511-1.1	N612W	Neutral	0.376
SLC26A4	O43511-1.1	N612Y	Neutral	0.398
SLC26A4	O43511-1.1	N613A	Pathogenic	0.537
SLC26A4	O43511-1.1	N613C	Pathogenic	0.809
SLC26A4	O43511-1.1	N613D	Neutral	0.36
SLC26A4	O43511-1.1	N613E	Neutral	0.453
SLC26A4	O43511-1.1	N613F	Neutral	0.457
SLC26A4	O43511-1.1	N613G	Neutral	0.121
SLC26A4	O43511-1.1	N613H	Neutral	0.174
SLC26A4	O43511-1.1	N613I	Pathogenic	0.578
SLC26A4	O43511-1.1	N613K	Neutral	0.183
SLC26A4	O43511-1.1	N613L	Pathogenic	0.588
SLC26A4	O43511-1.1	N613M	Neutral	0.46
SLC26A4	O43511-1.1	N613P	Pathogenic	0.737
SLC26A4	O43511-1.1	N613Q	Neutral	0.367
SLC26A4	O43511-1.1	N613R	Neutral	0.11
SLC26A4	O43511-1.1	N613S	Neutral	0.177
SLC26A4	O43511-1.1	N613T	Neutral	0.487
SLC26A4	O43511-1.1	N613V	Pathogenic	0.802
SLC26A4	O43511-1.1	N613W	Neutral	0.285
SLC26A4	O43511-1.1	N613Y	Neutral	0.305
SLC26A4	O43511-1.1	A614C	Neutral	0.31
SLC26A4	O43511-1.1	A614D	Pathogenic	0.553
SLC26A4	O43511-1.1	A614E	Neutral	0.223
SLC26A4	O43511-1.1	A614F	Neutral	0.127
SLC26A4	O43511-1.1	A614G	Neutral	0.341
SLC26A4	O43511-1.1	A614H	Neutral	0.341
SLC26A4	O43511-1.1	A614I	Neutral	0.106
SLC26A4	O43511-1.1	A614K	Neutral	0.072
SLC26A4	O43511-1.1	A614L	Neutral	0.109
SLC26A4	O43511-1.1	A614M	Neutral	0.128
SLC26A4	O43511-1.1	A614N	Pathogenic	0.513
SLC26A4	O43511-1.1	A614P	Neutral	0.454
SLC26A4	O43511-1.1	A614Q	Neutral	0.212
SLC26A4	O43511-1.1	A614R	Neutral	0.041
SLC26A4	O43511-1.1	A614S	Neutral	0.313
SLC26A4	O43511-1.1	A614T	Neutral	0.294
SLC26A4	O43511-1.1	A614V	Neutral	0.148
SLC26A4	O43511-1.1	A614W	Neutral	0.065
SLC26A4	O43511-1.1	A614Y	Neutral	0.132
SLC26A4	O43511-1.1	F615A	Neutral	0.257
SLC26A4	O43511-1.1	F615C	Pathogenic	0.513
SLC26A4	O43511-1.1	F615D	Pathogenic	0.575
SLC26A4	O43511-1.1	F615E	Pathogenic	0.762
SLC26A4	O43511-1.1	F615G	Neutral	0.207
SLC26A4	O43511-1.1	F615H	Pathogenic	0.616
SLC26A4	O43511-1.1	F615I	Pathogenic	0.664
SLC26A4	O43511-1.1	F615K	Pathogenic	0.901
SLC26A4	O43511-1.1	F615L	Pathogenic	0.657
SLC26A4	O43511-1.1	F615M	Pathogenic	0.615
SLC26A4	O43511-1.1	F615N	Pathogenic	0.644
SLC26A4	O43511-1.1	F615P	Pathogenic	0.822
SLC26A4	O43511-1.1	F615Q	Pathogenic	0.825
SLC26A4	O43511-1.1	F615R	Pathogenic	0.834
SLC26A4	O43511-1.1	F615S	Neutral	0.284
SLC26A4	O43511-1.1	F615T	Pathogenic	0.523
SLC26A4	O43511-1.1	F615V	Pathogenic	0.575
SLC26A4	O43511-1.1	F615W	Neutral	0.277
SLC26A4	O43511-1.1	F615Y	Neutral	0.182
SLC26A4	O43511-1.1	E616A	Pathogenic	0.799
SLC26A4	O43511-1.1	E616C	Pathogenic	0.983
SLC26A4	O43511-1.1	E616D	Pathogenic	0.665
SLC26A4	O43511-1.1	E616F	Pathogenic	0.949
SLC26A4	O43511-1.1	E616G	Pathogenic	0.793
SLC26A4	O43511-1.1	E616H	Pathogenic	0.904
SLC26A4	O43511-1.1	E616I	Pathogenic	0.968
SLC26A4	O43511-1.1	E616K	Pathogenic	0.719
SLC26A4	O43511-1.1	E616L	Pathogenic	0.97
SLC26A4	O43511-1.1	E616M	Pathogenic	0.95
SLC26A4	O43511-1.1	E616N	Pathogenic	0.912
SLC26A4	O43511-1.1	E616P	Pathogenic	0.906
SLC26A4	O43511-1.1	E616Q	Pathogenic	0.762
SLC26A4	O43511-1.1	E616R	Pathogenic	0.739
SLC26A4	O43511-1.1	E616S	Pathogenic	0.748
SLC26A4	O43511-1.1	E616T	Pathogenic	0.929
SLC26A4	O43511-1.1	E616V	Pathogenic	0.969
SLC26A4	O43511-1.1	E616W	Pathogenic	0.816
SLC26A4	O43511-1.1	E616Y	Pathogenic	0.907
SLC26A4	O43511-1.1	P617A	Pathogenic	0.53
SLC26A4	O43511-1.1	P617C	Pathogenic	0.919
SLC26A4	O43511-1.1	P617D	Pathogenic	0.668
SLC26A4	O43511-1.1	P617E	Neutral	0.484
SLC26A4	O43511-1.1	P617F	Pathogenic	0.724
SLC26A4	O43511-1.1	P617G	Neutral	0.461
SLC26A4	O43511-1.1	P617H	Pathogenic	0.628
SLC26A4	O43511-1.1	P617I	Pathogenic	0.681
SLC26A4	O43511-1.1	P617K	Neutral	0.202
SLC26A4	O43511-1.1	P617L	Pathogenic	0.69
SLC26A4	O43511-1.1	P617M	Pathogenic	0.57
SLC26A4	O43511-1.1	P617N	Pathogenic	0.775
SLC26A4	O43511-1.1	P617Q	Neutral	0.468
SLC26A4	O43511-1.1	P617R	Neutral	0.22
SLC26A4	O43511-1.1	P617S	Pathogenic	0.564
SLC26A4	O43511-1.1	P617T	Pathogenic	0.732
SLC26A4	O43511-1.1	P617V	Pathogenic	0.759
SLC26A4	O43511-1.1	P617W	Neutral	0.383
SLC26A4	O43511-1.1	P617Y	Pathogenic	0.579
SLC26A4	O43511-1.1	D618A	Pathogenic	0.911
SLC26A4	O43511-1.1	D618C	Pathogenic	0.974
SLC26A4	O43511-1.1	D618E	Pathogenic	0.544
SLC26A4	O43511-1.1	D618F	Pathogenic	0.825
SLC26A4	O43511-1.1	D618G	Pathogenic	0.71
SLC26A4	O43511-1.1	D618H	Pathogenic	0.827
SLC26A4	O43511-1.1	D618I	Pathogenic	0.885
SLC26A4	O43511-1.1	D618K	Pathogenic	0.743
SLC26A4	O43511-1.1	D618L	Pathogenic	0.942
SLC26A4	O43511-1.1	D618M	Pathogenic	0.906
SLC26A4	O43511-1.1	D618N	Pathogenic	0.809
SLC26A4	O43511-1.1	D618P	Pathogenic	0.925
SLC26A4	O43511-1.1	D618Q	Pathogenic	0.766
SLC26A4	O43511-1.1	D618R	Pathogenic	0.762
SLC26A4	O43511-1.1	D618S	Pathogenic	0.792
SLC26A4	O43511-1.1	D618T	Pathogenic	0.934
SLC26A4	O43511-1.1	D618V	Pathogenic	0.958
SLC26A4	O43511-1.1	D618W	Pathogenic	0.692
SLC26A4	O43511-1.1	D618Y	Pathogenic	0.832
SLC26A4	O43511-1.1	E619A	Pathogenic	0.657
SLC26A4	O43511-1.1	E619C	Pathogenic	0.966
SLC26A4	O43511-1.1	E619D	Neutral	0.488
SLC26A4	O43511-1.1	E619F	Pathogenic	0.9
SLC26A4	O43511-1.1	E619G	Pathogenic	0.647
SLC26A4	O43511-1.1	E619H	Pathogenic	0.819
SLC26A4	O43511-1.1	E619I	Pathogenic	0.936
SLC26A4	O43511-1.1	E619K	Pathogenic	0.551
SLC26A4	O43511-1.1	E619L	Pathogenic	0.938
SLC26A4	O43511-1.1	E619M	Pathogenic	0.901
SLC26A4	O43511-1.1	E619N	Pathogenic	0.833
SLC26A4	O43511-1.1	E619P	Pathogenic	0.822
SLC26A4	O43511-1.1	E619Q	Pathogenic	0.606
SLC26A4	O43511-1.1	E619R	Pathogenic	0.577
SLC26A4	O43511-1.1	E619S	Pathogenic	0.588
SLC26A4	O43511-1.1	E619T	Pathogenic	0.863
SLC26A4	O43511-1.1	E619V	Pathogenic	0.938
SLC26A4	O43511-1.1	E619W	Pathogenic	0.68
SLC26A4	O43511-1.1	E619Y	Pathogenic	0.824
SLC26A4	O43511-1.1	D620A	Pathogenic	0.987
SLC26A4	O43511-1.1	D620C	Pathogenic	0.997
SLC26A4	O43511-1.1	D620E	Pathogenic	0.901
SLC26A4	O43511-1.1	D620F	Pathogenic	0.973
SLC26A4	O43511-1.1	D620G	Pathogenic	0.949
SLC26A4	O43511-1.1	D620H	Pathogenic	0.973
SLC26A4	O43511-1.1	D620I	Pathogenic	0.983
SLC26A4	O43511-1.1	D620K	Pathogenic	0.957
SLC26A4	O43511-1.1	D620L	Pathogenic	0.992
SLC26A4	O43511-1.1	D620M	Pathogenic	0.987
SLC26A4	O43511-1.1	D620N	Pathogenic	0.97
SLC26A4	O43511-1.1	D620P	Pathogenic	0.989
SLC26A4	O43511-1.1	D620Q	Pathogenic	0.961
SLC26A4	O43511-1.1	D620R	Pathogenic	0.961
SLC26A4	O43511-1.1	D620S	Pathogenic	0.967
SLC26A4	O43511-1.1	D620T	Pathogenic	0.991
SLC26A4	O43511-1.1	D620V	Pathogenic	0.994
SLC26A4	O43511-1.1	D620W	Pathogenic	0.945
SLC26A4	O43511-1.1	D620Y	Pathogenic	0.974
SLC26A4	O43511-1.1	I621A	Neutral	0.014
SLC26A4	O43511-1.1	I621C	Neutral	0.041
SLC26A4	O43511-1.1	I621D	Neutral	0.099
SLC26A4	O43511-1.1	I621E	Neutral	0.207
SLC26A4	O43511-1.1	I621F	Neutral	0.09
SLC26A4	O43511-1.1	I621G	Neutral	0.041
SLC26A4	O43511-1.1	I621H	Neutral	0.345
SLC26A4	O43511-1.1	I621K	Neutral	0.215
SLC26A4	O43511-1.1	I621L	Neutral	0.037
SLC26A4	O43511-1.1	I621M	Neutral	0.061
SLC26A4	O43511-1.1	I621N	Neutral	0.128
SLC26A4	O43511-1.1	I621P	Neutral	0.158
SLC26A4	O43511-1.1	I621Q	Neutral	0.278
SLC26A4	O43511-1.1	I621R	Neutral	0.131
SLC26A4	O43511-1.1	I621S	Neutral	0.031
SLC26A4	O43511-1.1	I621T	Neutral	0.043
SLC26A4	O43511-1.1	I621V	Neutral	0.007
SLC26A4	O43511-1.1	I621W	Neutral	0.16
SLC26A4	O43511-1.1	I621Y	Neutral	0.099
SLC26A4	O43511-1.1	E622A	Neutral	0.288
SLC26A4	O43511-1.1	E622C	Pathogenic	0.856
SLC26A4	O43511-1.1	E622D	Neutral	0.168
SLC26A4	O43511-1.1	E622F	Pathogenic	0.655
SLC26A4	O43511-1.1	E622G	Neutral	0.279
SLC26A4	O43511-1.1	E622H	Neutral	0.488
SLC26A4	O43511-1.1	E622I	Pathogenic	0.756
SLC26A4	O43511-1.1	E622K	Neutral	0.206
SLC26A4	O43511-1.1	E622L	Pathogenic	0.763
SLC26A4	O43511-1.1	E622M	Pathogenic	0.658
SLC26A4	O43511-1.1	E622N	Pathogenic	0.514
SLC26A4	O43511-1.1	E622P	Neutral	0.493
SLC26A4	O43511-1.1	E622Q	Neutral	0.245
SLC26A4	O43511-1.1	E622R	Neutral	0.223
SLC26A4	O43511-1.1	E622S	Neutral	0.231
SLC26A4	O43511-1.1	E622T	Pathogenic	0.571
SLC26A4	O43511-1.1	E622V	Pathogenic	0.761
SLC26A4	O43511-1.1	E622W	Neutral	0.31
SLC26A4	O43511-1.1	E622Y	Neutral	0.498
SLC26A4	O43511-1.1	D623A	Neutral	0.366
SLC26A4	O43511-1.1	D623C	Pathogenic	0.678
SLC26A4	O43511-1.1	D623E	Neutral	0.063
SLC26A4	O43511-1.1	D623F	Neutral	0.21
SLC26A4	O43511-1.1	D623G	Neutral	0.121
SLC26A4	O43511-1.1	D623H	Neutral	0.211
SLC26A4	O43511-1.1	D623I	Neutral	0.302
SLC26A4	O43511-1.1	D623K	Neutral	0.139
SLC26A4	O43511-1.1	D623L	Neutral	0.475
SLC26A4	O43511-1.1	D623M	Neutral	0.351
SLC26A4	O43511-1.1	D623N	Neutral	0.192
SLC26A4	O43511-1.1	D623P	Neutral	0.409
SLC26A4	O43511-1.1	D623Q	Neutral	0.155
SLC26A4	O43511-1.1	D623R	Neutral	0.152
SLC26A4	O43511-1.1	D623S	Neutral	0.176
SLC26A4	O43511-1.1	D623T	Neutral	0.441
SLC26A4	O43511-1.1	D623V	Pathogenic	0.562
SLC26A4	O43511-1.1	D623W	Neutral	0.112
SLC26A4	O43511-1.1	D623Y	Neutral	0.218
SLC26A4	O43511-1.1	L624A	Neutral	0.0
SLC26A4	O43511-1.1	L624C	Neutral	0.0
SLC26A4	O43511-1.1	L624D	Neutral	0.0
SLC26A4	O43511-1.1	L624E	Neutral	0.001
SLC26A4	O43511-1.1	L624F	Neutral	0.0
SLC26A4	O43511-1.1	L624G	Neutral	0.0
SLC26A4	O43511-1.1	L624H	Neutral	0.001
SLC26A4	O43511-1.1	L624I	Neutral	0.0
SLC26A4	O43511-1.1	L624K	Neutral	0.0
SLC26A4	O43511-1.1	L624M	Neutral	0.0
SLC26A4	O43511-1.1	L624N	Neutral	0.0
SLC26A4	O43511-1.1	L624P	Neutral	0.0
SLC26A4	O43511-1.1	L624Q	Neutral	0.0
SLC26A4	O43511-1.1	L624R	Neutral	0.0
SLC26A4	O43511-1.1	L624S	Neutral	0.0
SLC26A4	O43511-1.1	L624T	Neutral	0.0
SLC26A4	O43511-1.1	L624V	Neutral	0.0
SLC26A4	O43511-1.1	L624W	Neutral	0.0
SLC26A4	O43511-1.1	L624Y	Neutral	0.0
SLC26A4	O43511-1.1	E625A	Pathogenic	0.941
SLC26A4	O43511-1.1	E625C	Pathogenic	0.996
SLC26A4	O43511-1.1	E625D	Pathogenic	0.888
SLC26A4	O43511-1.1	E625F	Pathogenic	0.987
SLC26A4	O43511-1.1	E625G	Pathogenic	0.938
SLC26A4	O43511-1.1	E625H	Pathogenic	0.974
SLC26A4	O43511-1.1	E625I	Pathogenic	0.992
SLC26A4	O43511-1.1	E625K	Pathogenic	0.91
SLC26A4	O43511-1.1	E625L	Pathogenic	0.992
SLC26A4	O43511-1.1	E625M	Pathogenic	0.987
SLC26A4	O43511-1.1	E625N	Pathogenic	0.976
SLC26A4	O43511-1.1	E625P	Pathogenic	0.975
SLC26A4	O43511-1.1	E625Q	Pathogenic	0.927
SLC26A4	O43511-1.1	E625R	Pathogenic	0.919
SLC26A4	O43511-1.1	E625S	Pathogenic	0.922
SLC26A4	O43511-1.1	E625T	Pathogenic	0.981
SLC26A4	O43511-1.1	E625V	Pathogenic	0.992
SLC26A4	O43511-1.1	E625W	Pathogenic	0.946
SLC26A4	O43511-1.1	E625Y	Pathogenic	0.975
SLC26A4	O43511-1.1	E626A	Pathogenic	0.869
SLC26A4	O43511-1.1	E626C	Pathogenic	0.99
SLC26A4	O43511-1.1	E626D	Pathogenic	0.767
SLC26A4	O43511-1.1	E626F	Pathogenic	0.969
SLC26A4	O43511-1.1	E626G	Pathogenic	0.864
SLC26A4	O43511-1.1	E626H	Pathogenic	0.94
SLC26A4	O43511-1.1	E626I	Pathogenic	0.981
SLC26A4	O43511-1.1	E626K	Pathogenic	0.809
SLC26A4	O43511-1.1	E626L	Pathogenic	0.981
SLC26A4	O43511-1.1	E626M	Pathogenic	0.969
SLC26A4	O43511-1.1	E626N	Pathogenic	0.945
SLC26A4	O43511-1.1	E626P	Pathogenic	0.941
SLC26A4	O43511-1.1	E626Q	Pathogenic	0.841
SLC26A4	O43511-1.1	E626R	Pathogenic	0.825
SLC26A4	O43511-1.1	E626S	Pathogenic	0.831
SLC26A4	O43511-1.1	E626T	Pathogenic	0.956
SLC26A4	O43511-1.1	E626V	Pathogenic	0.981
SLC26A4	O43511-1.1	E626W	Pathogenic	0.88
SLC26A4	O43511-1.1	E626Y	Pathogenic	0.942
SLC26A4	O43511-1.1	L627A	Pathogenic	0.596
SLC26A4	O43511-1.1	L627C	Pathogenic	0.818
SLC26A4	O43511-1.1	L627D	Pathogenic	0.959
SLC26A4	O43511-1.1	L627E	Pathogenic	0.965
SLC26A4	O43511-1.1	L627F	Pathogenic	0.906
SLC26A4	O43511-1.1	L627G	Pathogenic	0.818
SLC26A4	O43511-1.1	L627H	Pathogenic	0.982
SLC26A4	O43511-1.1	L627I	Pathogenic	0.797
SLC26A4	O43511-1.1	L627K	Pathogenic	0.935
SLC26A4	O43511-1.1	L627M	Pathogenic	0.773
SLC26A4	O43511-1.1	L627N	Pathogenic	0.939
SLC26A4	O43511-1.1	L627P	Pathogenic	0.952
SLC26A4	O43511-1.1	L627Q	Pathogenic	0.953
SLC26A4	O43511-1.1	L627R	Pathogenic	0.888
SLC26A4	O43511-1.1	L627S	Pathogenic	0.773
SLC26A4	O43511-1.1	L627T	Pathogenic	0.824
SLC26A4	O43511-1.1	L627V	Pathogenic	0.742
SLC26A4	O43511-1.1	L627W	Pathogenic	0.902
SLC26A4	O43511-1.1	L627Y	Pathogenic	0.92
SLC26A4	O43511-1.1	D628A	Pathogenic	0.975
SLC26A4	O43511-1.1	D628C	Pathogenic	0.993
SLC26A4	O43511-1.1	D628E	Pathogenic	0.821
SLC26A4	O43511-1.1	D628F	Pathogenic	0.948
SLC26A4	O43511-1.1	D628G	Pathogenic	0.904
SLC26A4	O43511-1.1	D628H	Pathogenic	0.949
SLC26A4	O43511-1.1	D628I	Pathogenic	0.968
SLC26A4	O43511-1.1	D628K	Pathogenic	0.918
SLC26A4	O43511-1.1	D628L	Pathogenic	0.984
SLC26A4	O43511-1.1	D628M	Pathogenic	0.974
SLC26A4	O43511-1.1	D628N	Pathogenic	0.942
SLC26A4	O43511-1.1	D628P	Pathogenic	0.979
SLC26A4	O43511-1.1	D628Q	Pathogenic	0.926
SLC26A4	O43511-1.1	D628R	Pathogenic	0.925
SLC26A4	O43511-1.1	D628S	Pathogenic	0.936
SLC26A4	O43511-1.1	D628T	Pathogenic	0.982
SLC26A4	O43511-1.1	D628V	Pathogenic	0.989
SLC26A4	O43511-1.1	D628W	Pathogenic	0.897
SLC26A4	O43511-1.1	D628Y	Pathogenic	0.95
SLC26A4	O43511-1.1	I629A	Neutral	0.021
SLC26A4	O43511-1.1	I629C	Neutral	0.06
SLC26A4	O43511-1.1	I629D	Neutral	0.142
SLC26A4	O43511-1.1	I629E	Neutral	0.281
SLC26A4	O43511-1.1	I629F	Neutral	0.128
SLC26A4	O43511-1.1	I629G	Neutral	0.06
SLC26A4	O43511-1.1	I629H	Neutral	0.442
SLC26A4	O43511-1.1	I629K	Neutral	0.291
SLC26A4	O43511-1.1	I629L	Neutral	0.055
SLC26A4	O43511-1.1	I629M	Neutral	0.089
SLC26A4	O43511-1.1	I629N	Neutral	0.181
SLC26A4	O43511-1.1	I629P	Neutral	0.219
SLC26A4	O43511-1.1	I629Q	Neutral	0.366
SLC26A4	O43511-1.1	I629R	Neutral	0.185
SLC26A4	O43511-1.1	I629S	Neutral	0.046
SLC26A4	O43511-1.1	I629T	Neutral	0.062
SLC26A4	O43511-1.1	I629V	Neutral	0.01
SLC26A4	O43511-1.1	I629W	Neutral	0.222
SLC26A4	O43511-1.1	I629Y	Neutral	0.141
SLC26A4	O43511-1.1	P630A	Pathogenic	0.994
SLC26A4	O43511-1.1	P630C	Pathogenic	0.999
SLC26A4	O43511-1.1	P630D	Pathogenic	0.997
SLC26A4	O43511-1.1	P630E	Pathogenic	0.993
SLC26A4	O43511-1.1	P630F	Pathogenic	0.997
SLC26A4	O43511-1.1	P630G	Pathogenic	0.992
SLC26A4	O43511-1.1	P630H	Pathogenic	0.996
SLC26A4	O43511-1.1	P630I	Pathogenic	0.997
SLC26A4	O43511-1.1	P630K	Pathogenic	0.973
SLC26A4	O43511-1.1	P630L	Pathogenic	0.997
SLC26A4	O43511-1.1	P630M	Pathogenic	0.995
SLC26A4	O43511-1.1	P630N	Pathogenic	0.998
SLC26A4	O43511-1.1	P630Q	Pathogenic	0.992
SLC26A4	O43511-1.1	P630R	Pathogenic	0.976
SLC26A4	O43511-1.1	P630S	Pathogenic	0.995
SLC26A4	O43511-1.1	P630T	Pathogenic	0.997
SLC26A4	O43511-1.1	P630V	Pathogenic	0.998
SLC26A4	O43511-1.1	P630W	Pathogenic	0.989
SLC26A4	O43511-1.1	P630Y	Pathogenic	0.995
SLC26A4	O43511-1.1	T631A	Pathogenic	0.841
SLC26A4	O43511-1.1	T631C	Pathogenic	0.951
SLC26A4	O43511-1.1	T631D	Pathogenic	0.956
SLC26A4	O43511-1.1	T631E	Pathogenic	0.923
SLC26A4	O43511-1.1	T631F	Pathogenic	0.854
SLC26A4	O43511-1.1	T631G	Pathogenic	0.893
SLC26A4	O43511-1.1	T631H	Pathogenic	0.956
SLC26A4	O43511-1.1	T631I	Pathogenic	0.826
SLC26A4	O43511-1.1	T631K	Pathogenic	0.765
SLC26A4	O43511-1.1	T631L	Pathogenic	0.832
SLC26A4	O43511-1.1	T631M	Pathogenic	0.856
SLC26A4	O43511-1.1	T631N	Pathogenic	0.916
SLC26A4	O43511-1.1	T631P	Pathogenic	0.962
SLC26A4	O43511-1.1	T631Q	Pathogenic	0.919
SLC26A4	O43511-1.1	T631R	Pathogenic	0.643
SLC26A4	O43511-1.1	T631S	Pathogenic	0.758
SLC26A4	O43511-1.1	T631V	Pathogenic	0.875
SLC26A4	O43511-1.1	T631W	Pathogenic	0.58
SLC26A4	O43511-1.1	T631Y	Pathogenic	0.86
SLC26A4	O43511-1.1	K632A	Neutral	0.21
SLC26A4	O43511-1.1	K632C	Pathogenic	0.662
SLC26A4	O43511-1.1	K632D	Pathogenic	0.544
SLC26A4	O43511-1.1	K632E	Neutral	0.387
SLC26A4	O43511-1.1	K632F	Pathogenic	0.929
SLC26A4	O43511-1.1	K632G	Neutral	0.204
SLC26A4	O43511-1.1	K632H	Pathogenic	0.74
SLC26A4	O43511-1.1	K632I	Pathogenic	0.888
SLC26A4	O43511-1.1	K632L	Pathogenic	0.804
SLC26A4	O43511-1.1	K632M	Pathogenic	0.71
SLC26A4	O43511-1.1	K632N	Neutral	0.411
SLC26A4	O43511-1.1	K632P	Neutral	0.391
SLC26A4	O43511-1.1	K632Q	Neutral	0.403
SLC26A4	O43511-1.1	K632R	Neutral	0.392
SLC26A4	O43511-1.1	K632S	Neutral	0.166
SLC26A4	O43511-1.1	K632T	Neutral	0.468
SLC26A4	O43511-1.1	K632V	Pathogenic	0.677
SLC26A4	O43511-1.1	K632W	Pathogenic	0.756
SLC26A4	O43511-1.1	K632Y	Pathogenic	0.872
SLC26A4	O43511-1.1	E633A	Pathogenic	0.784
SLC26A4	O43511-1.1	E633C	Pathogenic	0.982
SLC26A4	O43511-1.1	E633D	Pathogenic	0.643
SLC26A4	O43511-1.1	E633F	Pathogenic	0.944
SLC26A4	O43511-1.1	E633G	Pathogenic	0.776
SLC26A4	O43511-1.1	E633H	Pathogenic	0.895
SLC26A4	O43511-1.1	E633I	Pathogenic	0.965
SLC26A4	O43511-1.1	E633K	Pathogenic	0.699
SLC26A4	O43511-1.1	E633L	Pathogenic	0.967
SLC26A4	O43511-1.1	E633M	Pathogenic	0.945
SLC26A4	O43511-1.1	E633N	Pathogenic	0.904
SLC26A4	O43511-1.1	E633P	Pathogenic	0.897
SLC26A4	O43511-1.1	E633Q	Pathogenic	0.744
SLC26A4	O43511-1.1	E633R	Pathogenic	0.721
SLC26A4	O43511-1.1	E633S	Pathogenic	0.73
SLC26A4	O43511-1.1	E633T	Pathogenic	0.923
SLC26A4	O43511-1.1	E633V	Pathogenic	0.966
SLC26A4	O43511-1.1	E633W	Pathogenic	0.801
SLC26A4	O43511-1.1	E633Y	Pathogenic	0.899
SLC26A4	O43511-1.1	I634A	Neutral	0.049
SLC26A4	O43511-1.1	I634C	Neutral	0.136
SLC26A4	O43511-1.1	I634D	Neutral	0.288
SLC26A4	O43511-1.1	I634E	Neutral	0.489
SLC26A4	O43511-1.1	I634F	Neutral	0.265
SLC26A4	O43511-1.1	I634G	Neutral	0.135
SLC26A4	O43511-1.1	I634H	Pathogenic	0.659
SLC26A4	O43511-1.1	I634K	Pathogenic	0.5
SLC26A4	O43511-1.1	I634L	Neutral	0.124
SLC26A4	O43511-1.1	I634M	Neutral	0.192
SLC26A4	O43511-1.1	I634N	Neutral	0.351
SLC26A4	O43511-1.1	I634P	Neutral	0.406
SLC26A4	O43511-1.1	I634Q	Pathogenic	0.585
SLC26A4	O43511-1.1	I634R	Neutral	0.356
SLC26A4	O43511-1.1	I634S	Neutral	0.106
SLC26A4	O43511-1.1	I634T	Neutral	0.14
SLC26A4	O43511-1.1	I634V	Neutral	0.024
SLC26A4	O43511-1.1	I634W	Neutral	0.411
SLC26A4	O43511-1.1	I634Y	Neutral	0.286
SLC26A4	O43511-1.1	E635A	Pathogenic	0.728
SLC26A4	O43511-1.1	E635C	Pathogenic	0.975
SLC26A4	O43511-1.1	E635D	Pathogenic	0.572
SLC26A4	O43511-1.1	E635F	Pathogenic	0.926
SLC26A4	O43511-1.1	E635G	Pathogenic	0.72
SLC26A4	O43511-1.1	E635H	Pathogenic	0.864
SLC26A4	O43511-1.1	E635I	Pathogenic	0.954
SLC26A4	O43511-1.1	E635K	Pathogenic	0.632
SLC26A4	O43511-1.1	E635L	Pathogenic	0.955
SLC26A4	O43511-1.1	E635M	Pathogenic	0.927
SLC26A4	O43511-1.1	E635N	Pathogenic	0.875
SLC26A4	O43511-1.1	E635P	Pathogenic	0.866
SLC26A4	O43511-1.1	E635Q	Pathogenic	0.683
SLC26A4	O43511-1.1	E635R	Pathogenic	0.657
SLC26A4	O43511-1.1	E635S	Pathogenic	0.667
SLC26A4	O43511-1.1	E635T	Pathogenic	0.898
SLC26A4	O43511-1.1	E635V	Pathogenic	0.955
SLC26A4	O43511-1.1	E635W	Pathogenic	0.749
SLC26A4	O43511-1.1	E635Y	Pathogenic	0.868
SLC26A4	O43511-1.1	I636A	Neutral	0.176
SLC26A4	O43511-1.1	I636C	Neutral	0.394
SLC26A4	O43511-1.1	I636D	Pathogenic	0.626
SLC26A4	O43511-1.1	I636E	Pathogenic	0.799
SLC26A4	O43511-1.1	I636F	Pathogenic	0.599
SLC26A4	O43511-1.1	I636G	Neutral	0.394
SLC26A4	O43511-1.1	I636H	Pathogenic	0.889
SLC26A4	O43511-1.1	I636K	Pathogenic	0.806
SLC26A4	O43511-1.1	I636L	Neutral	0.371
SLC26A4	O43511-1.1	I636M	Neutral	0.497
SLC26A4	O43511-1.1	I636N	Pathogenic	0.692
SLC26A4	O43511-1.1	I636P	Pathogenic	0.74
SLC26A4	O43511-1.1	I636Q	Pathogenic	0.854
SLC26A4	O43511-1.1	I636R	Pathogenic	0.697
SLC26A4	O43511-1.1	I636S	Neutral	0.329
SLC26A4	O43511-1.1	I636T	Neutral	0.403
SLC26A4	O43511-1.1	I636V	Neutral	0.094
SLC26A4	O43511-1.1	I636W	Pathogenic	0.744
SLC26A4	O43511-1.1	I636Y	Pathogenic	0.625
SLC26A4	O43511-1.1	Q637A	Pathogenic	0.908
SLC26A4	O43511-1.1	Q637C	Pathogenic	0.986
SLC26A4	O43511-1.1	Q637D	Pathogenic	0.935
SLC26A4	O43511-1.1	Q637E	Pathogenic	0.894
SLC26A4	O43511-1.1	Q637F	Pathogenic	0.986
SLC26A4	O43511-1.1	Q637G	Pathogenic	0.904
SLC26A4	O43511-1.1	Q637H	Pathogenic	0.973
SLC26A4	O43511-1.1	Q637I	Pathogenic	0.992
SLC26A4	O43511-1.1	Q637K	Pathogenic	0.878
SLC26A4	O43511-1.1	Q637L	Pathogenic	0.984
SLC26A4	O43511-1.1	Q637M	Pathogenic	0.948
SLC26A4	O43511-1.1	Q637N	Pathogenic	0.95
SLC26A4	O43511-1.1	Q637P	Pathogenic	0.96
SLC26A4	O43511-1.1	Q637R	Pathogenic	0.799
SLC26A4	O43511-1.1	Q637S	Pathogenic	0.88
SLC26A4	O43511-1.1	Q637T	Pathogenic	0.97
SLC26A4	O43511-1.1	Q637V	Pathogenic	0.987
SLC26A4	O43511-1.1	Q637W	Pathogenic	0.895
SLC26A4	O43511-1.1	Q637Y	Pathogenic	0.95
SLC26A4	O43511-1.1	V638A	Neutral	0.283
SLC26A4	O43511-1.1	V638C	Pathogenic	0.708
SLC26A4	O43511-1.1	V638D	Pathogenic	0.862
SLC26A4	O43511-1.1	V638E	Pathogenic	0.837
SLC26A4	O43511-1.1	V638F	Pathogenic	0.565
SLC26A4	O43511-1.1	V638G	Pathogenic	0.547
SLC26A4	O43511-1.1	V638H	Pathogenic	0.902
SLC26A4	O43511-1.1	V638I	Neutral	0.115
SLC26A4	O43511-1.1	V638K	Pathogenic	0.581
SLC26A4	O43511-1.1	V638L	Neutral	0.353
SLC26A4	O43511-1.1	V638M	Neutral	0.396
SLC26A4	O43511-1.1	V638N	Pathogenic	0.893
SLC26A4	O43511-1.1	V638P	Pathogenic	0.841
SLC26A4	O43511-1.1	V638Q	Pathogenic	0.828
SLC26A4	O43511-1.1	V638R	Pathogenic	0.607
SLC26A4	O43511-1.1	V638S	Pathogenic	0.647
SLC26A4	O43511-1.1	V638T	Pathogenic	0.556
SLC26A4	O43511-1.1	V638W	Pathogenic	0.553
SLC26A4	O43511-1.1	V638Y	Pathogenic	0.528
SLC26A4	O43511-1.1	D639A	Pathogenic	0.986
SLC26A4	O43511-1.1	D639C	Pathogenic	0.996
SLC26A4	O43511-1.1	D639E	Pathogenic	0.891
SLC26A4	O43511-1.1	D639F	Pathogenic	0.97
SLC26A4	O43511-1.1	D639G	Pathogenic	0.944
SLC26A4	O43511-1.1	D639H	Pathogenic	0.97
SLC26A4	O43511-1.1	D639I	Pathogenic	0.982
SLC26A4	O43511-1.1	D639K	Pathogenic	0.952
SLC26A4	O43511-1.1	D639L	Pathogenic	0.991
SLC26A4	O43511-1.1	D639M	Pathogenic	0.985
SLC26A4	O43511-1.1	D639N	Pathogenic	0.967
SLC26A4	O43511-1.1	D639P	Pathogenic	0.988
SLC26A4	O43511-1.1	D639Q	Pathogenic	0.957
SLC26A4	O43511-1.1	D639R	Pathogenic	0.957
SLC26A4	O43511-1.1	D639S	Pathogenic	0.963
SLC26A4	O43511-1.1	D639T	Pathogenic	0.99
SLC26A4	O43511-1.1	D639V	Pathogenic	0.994
SLC26A4	O43511-1.1	D639W	Pathogenic	0.939
SLC26A4	O43511-1.1	D639Y	Pathogenic	0.972
SLC26A4	O43511-1.1	W640A	Pathogenic	0.997
SLC26A4	O43511-1.1	W640C	Pathogenic	0.998
SLC26A4	O43511-1.1	W640D	Pathogenic	0.999
SLC26A4	O43511-1.1	W640E	Pathogenic	0.999
SLC26A4	O43511-1.1	W640F	Pathogenic	0.999
SLC26A4	O43511-1.1	W640G	Pathogenic	0.987
SLC26A4	O43511-1.1	W640H	Pathogenic	0.999
SLC26A4	O43511-1.1	W640I	Pathogenic	1.0
SLC26A4	O43511-1.1	W640K	Pathogenic	1.0
SLC26A4	O43511-1.1	W640L	Pathogenic	1.0
SLC26A4	O43511-1.1	W640M	Pathogenic	0.999
SLC26A4	O43511-1.1	W640N	Pathogenic	1.0
SLC26A4	O43511-1.1	W640P	Pathogenic	1.0
SLC26A4	O43511-1.1	W640Q	Pathogenic	0.999
SLC26A4	O43511-1.1	W640R	Pathogenic	1.0
SLC26A4	O43511-1.1	W640S	Pathogenic	0.998
SLC26A4	O43511-1.1	W640T	Pathogenic	0.998
SLC26A4	O43511-1.1	W640V	Pathogenic	1.0
SLC26A4	O43511-1.1	W640Y	Pathogenic	0.998
SLC26A4	O43511-1.1	N641A	Pathogenic	0.979
SLC26A4	O43511-1.1	N641C	Pathogenic	0.994
SLC26A4	O43511-1.1	N641D	Pathogenic	0.958
SLC26A4	O43511-1.1	N641E	Pathogenic	0.971
SLC26A4	O43511-1.1	N641F	Pathogenic	0.972
SLC26A4	O43511-1.1	N641G	Pathogenic	0.848
SLC26A4	O43511-1.1	N641H	Pathogenic	0.895
SLC26A4	O43511-1.1	N641I	Pathogenic	0.982
SLC26A4	O43511-1.1	N641K	Pathogenic	0.901
SLC26A4	O43511-1.1	N641L	Pathogenic	0.983
SLC26A4	O43511-1.1	N641M	Pathogenic	0.972
SLC26A4	O43511-1.1	N641P	Pathogenic	0.991
SLC26A4	O43511-1.1	N641Q	Pathogenic	0.959
SLC26A4	O43511-1.1	N641R	Pathogenic	0.834
SLC26A4	O43511-1.1	N641S	Pathogenic	0.897
SLC26A4	O43511-1.1	N641T	Pathogenic	0.975
SLC26A4	O43511-1.1	N641V	Pathogenic	0.994
SLC26A4	O43511-1.1	N641W	Pathogenic	0.942
SLC26A4	O43511-1.1	N641Y	Pathogenic	0.947
SLC26A4	O43511-1.1	S642A	Neutral	0.354
SLC26A4	O43511-1.1	S642C	Pathogenic	0.555
SLC26A4	O43511-1.1	S642D	Neutral	0.356
SLC26A4	O43511-1.1	S642E	Neutral	0.205
SLC26A4	O43511-1.1	S642F	Neutral	0.167
SLC26A4	O43511-1.1	S642G	Neutral	0.345
SLC26A4	O43511-1.1	S642H	Neutral	0.29
SLC26A4	O43511-1.1	S642I	Neutral	0.247
SLC26A4	O43511-1.1	S642K	Neutral	0.065
SLC26A4	O43511-1.1	S642L	Neutral	0.254
SLC26A4	O43511-1.1	S642M	Neutral	0.169
SLC26A4	O43511-1.1	S642N	Neutral	0.19
SLC26A4	O43511-1.1	S642P	Pathogenic	0.535
SLC26A4	O43511-1.1	S642Q	Neutral	0.195
SLC26A4	O43511-1.1	S642R	Neutral	0.072
SLC26A4	O43511-1.1	S642T	Neutral	0.229
SLC26A4	O43511-1.1	S642V	Neutral	0.492
SLC26A4	O43511-1.1	S642W	Neutral	0.087
SLC26A4	O43511-1.1	S642Y	Neutral	0.174
SLC26A4	O43511-1.1	E643A	Pathogenic	0.675
SLC26A4	O43511-1.1	E643C	Pathogenic	0.968
SLC26A4	O43511-1.1	E643D	Pathogenic	0.508
SLC26A4	O43511-1.1	E643F	Pathogenic	0.907
SLC26A4	O43511-1.1	E643G	Pathogenic	0.665
SLC26A4	O43511-1.1	E643H	Pathogenic	0.83
SLC26A4	O43511-1.1	E643I	Pathogenic	0.941
SLC26A4	O43511-1.1	E643K	Pathogenic	0.571
SLC26A4	O43511-1.1	E643L	Pathogenic	0.943
SLC26A4	O43511-1.1	E643M	Pathogenic	0.908
SLC26A4	O43511-1.1	E643N	Pathogenic	0.844
SLC26A4	O43511-1.1	E643P	Pathogenic	0.833
SLC26A4	O43511-1.1	E643Q	Pathogenic	0.625
SLC26A4	O43511-1.1	E643R	Pathogenic	0.596
SLC26A4	O43511-1.1	E643S	Pathogenic	0.607
SLC26A4	O43511-1.1	E643T	Pathogenic	0.872
SLC26A4	O43511-1.1	E643V	Pathogenic	0.942
SLC26A4	O43511-1.1	E643W	Pathogenic	0.697
SLC26A4	O43511-1.1	E643Y	Pathogenic	0.836
SLC26A4	O43511-1.1	L644A	Pathogenic	0.776
SLC26A4	O43511-1.1	L644C	Pathogenic	0.914
SLC26A4	O43511-1.1	L644D	Pathogenic	0.982
SLC26A4	O43511-1.1	L644E	Pathogenic	0.985
SLC26A4	O43511-1.1	L644F	Pathogenic	0.958
SLC26A4	O43511-1.1	L644G	Pathogenic	0.914
SLC26A4	O43511-1.1	L644H	Pathogenic	0.992
SLC26A4	O43511-1.1	L644I	Pathogenic	0.902
SLC26A4	O43511-1.1	L644K	Pathogenic	0.971
SLC26A4	O43511-1.1	L644M	Pathogenic	0.889
SLC26A4	O43511-1.1	L644N	Pathogenic	0.973
SLC26A4	O43511-1.1	L644P	Pathogenic	0.979
SLC26A4	O43511-1.1	L644Q	Pathogenic	0.979
SLC26A4	O43511-1.1	L644R	Pathogenic	0.949
SLC26A4	O43511-1.1	L644S	Pathogenic	0.889
SLC26A4	O43511-1.1	L644T	Pathogenic	0.917
SLC26A4	O43511-1.1	L644V	Pathogenic	0.871
SLC26A4	O43511-1.1	L644W	Pathogenic	0.956
SLC26A4	O43511-1.1	L644Y	Pathogenic	0.964
SLC26A4	O43511-1.1	P645A	Pathogenic	0.995
SLC26A4	O43511-1.1	P645C	Pathogenic	0.999
SLC26A4	O43511-1.1	P645D	Pathogenic	0.997
SLC26A4	O43511-1.1	P645E	Pathogenic	0.994
SLC26A4	O43511-1.1	P645F	Pathogenic	0.998
SLC26A4	O43511-1.1	P645G	Pathogenic	0.993
SLC26A4	O43511-1.1	P645H	Pathogenic	0.997
SLC26A4	O43511-1.1	P645I	Pathogenic	0.997
SLC26A4	O43511-1.1	P645K	Pathogenic	0.978
SLC26A4	O43511-1.1	P645L	Pathogenic	0.997
SLC26A4	O43511-1.1	P645M	Pathogenic	0.996
SLC26A4	O43511-1.1	P645N	Pathogenic	0.998
SLC26A4	O43511-1.1	P645Q	Pathogenic	0.994
SLC26A4	O43511-1.1	P645R	Pathogenic	0.98
SLC26A4	O43511-1.1	P645S	Pathogenic	0.996
SLC26A4	O43511-1.1	P645T	Pathogenic	0.998
SLC26A4	O43511-1.1	P645V	Pathogenic	0.998
SLC26A4	O43511-1.1	P645W	Pathogenic	0.991
SLC26A4	O43511-1.1	P645Y	Pathogenic	0.996
SLC26A4	O43511-1.1	V646A	Neutral	0.077
SLC26A4	O43511-1.1	V646C	Neutral	0.34
SLC26A4	O43511-1.1	V646D	Pathogenic	0.57
SLC26A4	O43511-1.1	V646E	Pathogenic	0.522
SLC26A4	O43511-1.1	V646F	Neutral	0.216
SLC26A4	O43511-1.1	V646G	Neutral	0.204
SLC26A4	O43511-1.1	V646H	Pathogenic	0.663
SLC26A4	O43511-1.1	V646I	Neutral	0.027
SLC26A4	O43511-1.1	V646K	Neutral	0.227
SLC26A4	O43511-1.1	V646L	Neutral	0.104
SLC26A4	O43511-1.1	V646M	Neutral	0.122
SLC26A4	O43511-1.1	V646N	Pathogenic	0.639
SLC26A4	O43511-1.1	V646P	Pathogenic	0.528
SLC26A4	O43511-1.1	V646Q	Pathogenic	0.506
SLC26A4	O43511-1.1	V646R	Neutral	0.247
SLC26A4	O43511-1.1	V646S	Neutral	0.28
SLC26A4	O43511-1.1	V646T	Neutral	0.21
SLC26A4	O43511-1.1	V646W	Neutral	0.208
SLC26A4	O43511-1.1	V646Y	Neutral	0.192
SLC26A4	O43511-1.1	K647A	Neutral	0.105
SLC26A4	O43511-1.1	K647C	Neutral	0.463
SLC26A4	O43511-1.1	K647D	Neutral	0.344
SLC26A4	O43511-1.1	K647E	Neutral	0.218
SLC26A4	O43511-1.1	K647F	Pathogenic	0.852
SLC26A4	O43511-1.1	K647G	Neutral	0.101
SLC26A4	O43511-1.1	K647H	Pathogenic	0.557
SLC26A4	O43511-1.1	K647I	Pathogenic	0.777
SLC26A4	O43511-1.1	K647L	Pathogenic	0.644
SLC26A4	O43511-1.1	K647M	Pathogenic	0.519
SLC26A4	O43511-1.1	K647N	Neutral	0.235
SLC26A4	O43511-1.1	K647P	Neutral	0.221
SLC26A4	O43511-1.1	K647Q	Neutral	0.229
SLC26A4	O43511-1.1	K647R	Neutral	0.221
SLC26A4	O43511-1.1	K647S	Neutral	0.08
SLC26A4	O43511-1.1	K647T	Neutral	0.279
SLC26A4	O43511-1.1	K647V	Neutral	0.48
SLC26A4	O43511-1.1	K647W	Pathogenic	0.577
SLC26A4	O43511-1.1	K647Y	Pathogenic	0.751
SLC26A4	O43511-1.1	V648A	Neutral	0.234
SLC26A4	O43511-1.1	V648C	Pathogenic	0.652
SLC26A4	O43511-1.1	V648D	Pathogenic	0.829
SLC26A4	O43511-1.1	V648E	Pathogenic	0.799
SLC26A4	O43511-1.1	V648F	Pathogenic	0.501
SLC26A4	O43511-1.1	V648G	Neutral	0.483
SLC26A4	O43511-1.1	V648H	Pathogenic	0.877
SLC26A4	O43511-1.1	V648I	Neutral	0.091
SLC26A4	O43511-1.1	V648K	Pathogenic	0.518
SLC26A4	O43511-1.1	V648L	Neutral	0.297
SLC26A4	O43511-1.1	V648M	Neutral	0.336
SLC26A4	O43511-1.1	V648N	Pathogenic	0.866
SLC26A4	O43511-1.1	V648P	Pathogenic	0.803
SLC26A4	O43511-1.1	V648Q	Pathogenic	0.788
SLC26A4	O43511-1.1	V648R	Pathogenic	0.544
SLC26A4	O43511-1.1	V648S	Pathogenic	0.586
SLC26A4	O43511-1.1	V648T	Neutral	0.492
SLC26A4	O43511-1.1	V648W	Neutral	0.489
SLC26A4	O43511-1.1	V648Y	Neutral	0.464
SLC26A4	O43511-1.1	N649A	Pathogenic	0.646
SLC26A4	O43511-1.1	N649C	Pathogenic	0.87
SLC26A4	O43511-1.1	N649D	Neutral	0.47
SLC26A4	O43511-1.1	N649E	Pathogenic	0.566
SLC26A4	O43511-1.1	N649F	Pathogenic	0.569
SLC26A4	O43511-1.1	N649G	Neutral	0.178
SLC26A4	O43511-1.1	N649H	Neutral	0.249
SLC26A4	O43511-1.1	N649I	Pathogenic	0.683
SLC26A4	O43511-1.1	N649K	Neutral	0.26
SLC26A4	O43511-1.1	N649L	Pathogenic	0.692
SLC26A4	O43511-1.1	N649M	Pathogenic	0.572
SLC26A4	O43511-1.1	N649P	Pathogenic	0.815
SLC26A4	O43511-1.1	N649Q	Neutral	0.477
SLC26A4	O43511-1.1	N649R	Neutral	0.163
SLC26A4	O43511-1.1	N649S	Neutral	0.252
SLC26A4	O43511-1.1	N649T	Pathogenic	0.599
SLC26A4	O43511-1.1	N649V	Pathogenic	0.864
SLC26A4	O43511-1.1	N649W	Neutral	0.386
SLC26A4	O43511-1.1	N649Y	Neutral	0.408
SLC26A4	O43511-1.1	V650A	Pathogenic	0.785
SLC26A4	O43511-1.1	V650C	Pathogenic	0.957
SLC26A4	O43511-1.1	V650D	Pathogenic	0.983
SLC26A4	O43511-1.1	V650E	Pathogenic	0.979
SLC26A4	O43511-1.1	V650F	Pathogenic	0.923
SLC26A4	O43511-1.1	V650G	Pathogenic	0.918
SLC26A4	O43511-1.1	V650H	Pathogenic	0.988
SLC26A4	O43511-1.1	V650I	Pathogenic	0.546
SLC26A4	O43511-1.1	V650K	Pathogenic	0.928
SLC26A4	O43511-1.1	V650L	Pathogenic	0.835
SLC26A4	O43511-1.1	V650M	Pathogenic	0.858
SLC26A4	O43511-1.1	V650N	Pathogenic	0.987
SLC26A4	O43511-1.1	V650P	Pathogenic	0.98
SLC26A4	O43511-1.1	V650Q	Pathogenic	0.978
SLC26A4	O43511-1.1	V650R	Pathogenic	0.934
SLC26A4	O43511-1.1	V650S	Pathogenic	0.944
SLC26A4	O43511-1.1	V650T	Pathogenic	0.921
SLC26A4	O43511-1.1	V650W	Pathogenic	0.92
SLC26A4	O43511-1.1	V650Y	Pathogenic	0.912
SLC26A4	O43511-1.1	P651A	Pathogenic	0.998
SLC26A4	O43511-1.1	P651C	Pathogenic	1.0
SLC26A4	O43511-1.1	P651D	Pathogenic	0.999
SLC26A4	O43511-1.1	P651E	Pathogenic	0.998
SLC26A4	O43511-1.1	P651F	Pathogenic	0.999
SLC26A4	O43511-1.1	P651G	Pathogenic	0.998
SLC26A4	O43511-1.1	P651H	Pathogenic	0.999
SLC26A4	O43511-1.1	P651I	Pathogenic	0.999
SLC26A4	O43511-1.1	P651K	Pathogenic	0.993
SLC26A4	O43511-1.1	P651L	Pathogenic	0.999
SLC26A4	O43511-1.1	P651M	Pathogenic	0.999
SLC26A4	O43511-1.1	P651N	Pathogenic	0.999
SLC26A4	O43511-1.1	P651Q	Pathogenic	0.998
SLC26A4	O43511-1.1	P651R	Pathogenic	0.993
SLC26A4	O43511-1.1	P651S	Pathogenic	0.999
SLC26A4	O43511-1.1	P651T	Pathogenic	0.999
SLC26A4	O43511-1.1	P651V	Pathogenic	0.999
SLC26A4	O43511-1.1	P651W	Pathogenic	0.997
SLC26A4	O43511-1.1	P651Y	Pathogenic	0.999
SLC26A4	O43511-1.1	K652A	Pathogenic	0.558
SLC26A4	O43511-1.1	K652C	Pathogenic	0.903
SLC26A4	O43511-1.1	K652D	Pathogenic	0.85
SLC26A4	O43511-1.1	K652E	Pathogenic	0.75
SLC26A4	O43511-1.1	K652F	Pathogenic	0.984
SLC26A4	O43511-1.1	K652G	Pathogenic	0.548
SLC26A4	O43511-1.1	K652H	Pathogenic	0.931
SLC26A4	O43511-1.1	K652I	Pathogenic	0.974
SLC26A4	O43511-1.1	K652L	Pathogenic	0.951
SLC26A4	O43511-1.1	K652M	Pathogenic	0.921
SLC26A4	O43511-1.1	K652N	Pathogenic	0.768
SLC26A4	O43511-1.1	K652P	Pathogenic	0.753
SLC26A4	O43511-1.1	K652Q	Pathogenic	0.762
SLC26A4	O43511-1.1	K652R	Pathogenic	0.754
SLC26A4	O43511-1.1	K652S	Neutral	0.485
SLC26A4	O43511-1.1	K652T	Pathogenic	0.807
SLC26A4	O43511-1.1	K652V	Pathogenic	0.909
SLC26A4	O43511-1.1	K652W	Pathogenic	0.936
SLC26A4	O43511-1.1	K652Y	Pathogenic	0.97
SLC26A4	O43511-1.1	V653A	Pathogenic	0.534
SLC26A4	O43511-1.1	V653C	Pathogenic	0.875
SLC26A4	O43511-1.1	V653D	Pathogenic	0.948
SLC26A4	O43511-1.1	V653E	Pathogenic	0.937
SLC26A4	O43511-1.1	V653F	Pathogenic	0.79
SLC26A4	O43511-1.1	V653G	Pathogenic	0.777
SLC26A4	O43511-1.1	V653H	Pathogenic	0.964
SLC26A4	O43511-1.1	V653I	Neutral	0.274
SLC26A4	O43511-1.1	V653K	Pathogenic	0.801
SLC26A4	O43511-1.1	V653L	Pathogenic	0.613
SLC26A4	O43511-1.1	V653M	Pathogenic	0.655
SLC26A4	O43511-1.1	V653N	Pathogenic	0.96
SLC26A4	O43511-1.1	V653P	Pathogenic	0.939
SLC26A4	O43511-1.1	V653Q	Pathogenic	0.933
SLC26A4	O43511-1.1	V653R	Pathogenic	0.817
SLC26A4	O43511-1.1	V653S	Pathogenic	0.841
SLC26A4	O43511-1.1	V653T	Pathogenic	0.784
SLC26A4	O43511-1.1	V653W	Pathogenic	0.782
SLC26A4	O43511-1.1	V653Y	Pathogenic	0.764
SLC26A4	O43511-1.1	P654A	Pathogenic	0.653
SLC26A4	O43511-1.1	P654C	Pathogenic	0.95
SLC26A4	O43511-1.1	P654D	Pathogenic	0.77
SLC26A4	O43511-1.1	P654E	Pathogenic	0.61
SLC26A4	O43511-1.1	P654F	Pathogenic	0.814
SLC26A4	O43511-1.1	P654G	Pathogenic	0.587
SLC26A4	O43511-1.1	P654H	Pathogenic	0.738
SLC26A4	O43511-1.1	P654I	Pathogenic	0.781
SLC26A4	O43511-1.1	P654K	Neutral	0.297
SLC26A4	O43511-1.1	P654L	Pathogenic	0.787
SLC26A4	O43511-1.1	P654M	Pathogenic	0.688
SLC26A4	O43511-1.1	P654N	Pathogenic	0.851
SLC26A4	O43511-1.1	P654Q	Pathogenic	0.594
SLC26A4	O43511-1.1	P654R	Neutral	0.319
SLC26A4	O43511-1.1	P654S	Pathogenic	0.683
SLC26A4	O43511-1.1	P654T	Pathogenic	0.82
SLC26A4	O43511-1.1	P654V	Pathogenic	0.84
SLC26A4	O43511-1.1	P654W	Pathogenic	0.508
SLC26A4	O43511-1.1	P654Y	Pathogenic	0.696
SLC26A4	O43511-1.1	I655A	Pathogenic	0.597
SLC26A4	O43511-1.1	I655C	Pathogenic	0.819
SLC26A4	O43511-1.1	I655D	Pathogenic	0.921
SLC26A4	O43511-1.1	I655E	Pathogenic	0.965
SLC26A4	O43511-1.1	I655F	Pathogenic	0.912
SLC26A4	O43511-1.1	I655G	Pathogenic	0.819
SLC26A4	O43511-1.1	I655H	Pathogenic	0.982
SLC26A4	O43511-1.1	I655K	Pathogenic	0.967
SLC26A4	O43511-1.1	I655L	Pathogenic	0.804
SLC26A4	O43511-1.1	I655M	Pathogenic	0.873
SLC26A4	O43511-1.1	I655N	Pathogenic	0.94
SLC26A4	O43511-1.1	I655P	Pathogenic	0.952
SLC26A4	O43511-1.1	I655Q	Pathogenic	0.976
SLC26A4	O43511-1.1	I655R	Pathogenic	0.941
SLC26A4	O43511-1.1	I655S	Pathogenic	0.774
SLC26A4	O43511-1.1	I655T	Pathogenic	0.824
SLC26A4	O43511-1.1	I655V	Neutral	0.418
SLC26A4	O43511-1.1	I655W	Pathogenic	0.953
SLC26A4	O43511-1.1	I655Y	Pathogenic	0.921
SLC26A4	O43511-1.1	H656A	Pathogenic	1.0
SLC26A4	O43511-1.1	H656C	Pathogenic	1.0
SLC26A4	O43511-1.1	H656D	Pathogenic	1.0
SLC26A4	O43511-1.1	H656E	Pathogenic	1.0
SLC26A4	O43511-1.1	H656F	Pathogenic	1.0
SLC26A4	O43511-1.1	H656G	Pathogenic	0.999
SLC26A4	O43511-1.1	H656I	Pathogenic	1.0
SLC26A4	O43511-1.1	H656K	Pathogenic	1.0
SLC26A4	O43511-1.1	H656L	Pathogenic	1.0
SLC26A4	O43511-1.1	H656M	Pathogenic	1.0
SLC26A4	O43511-1.1	H656N	Pathogenic	0.999
SLC26A4	O43511-1.1	H656P	Pathogenic	1.0
SLC26A4	O43511-1.1	H656Q	Pathogenic	1.0
SLC26A4	O43511-1.1	H656R	Pathogenic	0.999
SLC26A4	O43511-1.1	H656S	Pathogenic	1.0
SLC26A4	O43511-1.1	H656T	Pathogenic	1.0
SLC26A4	O43511-1.1	H656V	Pathogenic	1.0
SLC26A4	O43511-1.1	H656W	Pathogenic	1.0
SLC26A4	O43511-1.1	H656Y	Pathogenic	0.998
SLC26A4	O43511-1.1	S657A	Pathogenic	0.992
SLC26A4	O43511-1.1	S657C	Pathogenic	0.996
SLC26A4	O43511-1.1	S657D	Pathogenic	0.992
SLC26A4	O43511-1.1	S657E	Pathogenic	0.982
SLC26A4	O43511-1.1	S657F	Pathogenic	0.978
SLC26A4	O43511-1.1	S657G	Pathogenic	0.991
SLC26A4	O43511-1.1	S657H	Pathogenic	0.989
SLC26A4	O43511-1.1	S657I	Pathogenic	0.986
SLC26A4	O43511-1.1	S657K	Pathogenic	0.938
SLC26A4	O43511-1.1	S657L	Pathogenic	0.987
SLC26A4	O43511-1.1	S657M	Pathogenic	0.978
SLC26A4	O43511-1.1	S657N	Pathogenic	0.981
SLC26A4	O43511-1.1	S657P	Pathogenic	0.996
SLC26A4	O43511-1.1	S657Q	Pathogenic	0.981
SLC26A4	O43511-1.1	S657R	Pathogenic	0.944
SLC26A4	O43511-1.1	S657T	Pathogenic	0.985
SLC26A4	O43511-1.1	S657V	Pathogenic	0.995
SLC26A4	O43511-1.1	S657W	Pathogenic	0.954
SLC26A4	O43511-1.1	S657Y	Pathogenic	0.979
SLC26A4	O43511-1.1	L658A	Pathogenic	0.706
SLC26A4	O43511-1.1	L658C	Pathogenic	0.88
SLC26A4	O43511-1.1	L658D	Pathogenic	0.974
SLC26A4	O43511-1.1	L658E	Pathogenic	0.978
SLC26A4	O43511-1.1	L658F	Pathogenic	0.94
SLC26A4	O43511-1.1	L658G	Pathogenic	0.88
SLC26A4	O43511-1.1	L658H	Pathogenic	0.989
SLC26A4	O43511-1.1	L658I	Pathogenic	0.864
SLC26A4	O43511-1.1	L658K	Pathogenic	0.959
SLC26A4	O43511-1.1	L658M	Pathogenic	0.847
SLC26A4	O43511-1.1	L658N	Pathogenic	0.962
SLC26A4	O43511-1.1	L658P	Pathogenic	0.97
SLC26A4	O43511-1.1	L658Q	Pathogenic	0.97
SLC26A4	O43511-1.1	L658R	Pathogenic	0.928
SLC26A4	O43511-1.1	L658S	Pathogenic	0.847
SLC26A4	O43511-1.1	L658T	Pathogenic	0.884
SLC26A4	O43511-1.1	L658V	Pathogenic	0.824
SLC26A4	O43511-1.1	L658W	Pathogenic	0.938
SLC26A4	O43511-1.1	L658Y	Pathogenic	0.949
SLC26A4	O43511-1.1	V659A	Neutral	0.419
SLC26A4	O43511-1.1	V659C	Pathogenic	0.816
SLC26A4	O43511-1.1	V659D	Pathogenic	0.919
SLC26A4	O43511-1.1	V659E	Pathogenic	0.904
SLC26A4	O43511-1.1	V659F	Pathogenic	0.703
SLC26A4	O43511-1.1	V659G	Pathogenic	0.688
SLC26A4	O43511-1.1	V659H	Pathogenic	0.944
SLC26A4	O43511-1.1	V659I	Neutral	0.192
SLC26A4	O43511-1.1	V659K	Pathogenic	0.717
SLC26A4	O43511-1.1	V659L	Neutral	0.499
SLC26A4	O43511-1.1	V659M	Pathogenic	0.545
SLC26A4	O43511-1.1	V659N	Pathogenic	0.938
SLC26A4	O43511-1.1	V659P	Pathogenic	0.906
SLC26A4	O43511-1.1	V659Q	Pathogenic	0.898
SLC26A4	O43511-1.1	V659R	Pathogenic	0.738
SLC26A4	O43511-1.1	V659S	Pathogenic	0.77
SLC26A4	O43511-1.1	V659T	Pathogenic	0.696
SLC26A4	O43511-1.1	V659W	Pathogenic	0.693
SLC26A4	O43511-1.1	V659Y	Pathogenic	0.671
SLC26A4	O43511-1.1	L660A	Pathogenic	0.895
SLC26A4	O43511-1.1	L660C	Pathogenic	0.963
SLC26A4	O43511-1.1	L660D	Pathogenic	0.993
SLC26A4	O43511-1.1	L660E	Pathogenic	0.994
SLC26A4	O43511-1.1	L660F	Pathogenic	0.982
SLC26A4	O43511-1.1	L660G	Pathogenic	0.963
SLC26A4	O43511-1.1	L660H	Pathogenic	0.997
SLC26A4	O43511-1.1	L660I	Pathogenic	0.958
SLC26A4	O43511-1.1	L660K	Pathogenic	0.988
SLC26A4	O43511-1.1	L660M	Pathogenic	0.951
SLC26A4	O43511-1.1	L660N	Pathogenic	0.989
SLC26A4	O43511-1.1	L660P	Pathogenic	0.991
SLC26A4	O43511-1.1	L660Q	Pathogenic	0.991
SLC26A4	O43511-1.1	L660R	Pathogenic	0.979
SLC26A4	O43511-1.1	L660S	Pathogenic	0.951
SLC26A4	O43511-1.1	L660T	Pathogenic	0.964
SLC26A4	O43511-1.1	L660V	Pathogenic	0.943
SLC26A4	O43511-1.1	L660W	Pathogenic	0.982
SLC26A4	O43511-1.1	L660Y	Pathogenic	0.985
SLC26A4	O43511-1.1	D661A	Pathogenic	0.999
SLC26A4	O43511-1.1	D661C	Pathogenic	1.0
SLC26A4	O43511-1.1	D661E	Pathogenic	0.99
SLC26A4	O43511-1.1	D661F	Pathogenic	0.998
SLC26A4	O43511-1.1	D661G	Pathogenic	0.995
SLC26A4	O43511-1.1	D661H	Pathogenic	0.998
SLC26A4	O43511-1.1	D661I	Pathogenic	0.999
SLC26A4	O43511-1.1	D661K	Pathogenic	0.996
SLC26A4	O43511-1.1	D661L	Pathogenic	0.999
SLC26A4	O43511-1.1	D661M	Pathogenic	0.999
SLC26A4	O43511-1.1	D661N	Pathogenic	0.997
SLC26A4	O43511-1.1	D661P	Pathogenic	0.999
SLC26A4	O43511-1.1	D661Q	Pathogenic	0.996
SLC26A4	O43511-1.1	D661R	Pathogenic	0.996
SLC26A4	O43511-1.1	D661S	Pathogenic	0.997
SLC26A4	O43511-1.1	D661T	Pathogenic	0.999
SLC26A4	O43511-1.1	D661V	Pathogenic	0.999
SLC26A4	O43511-1.1	D661W	Pathogenic	0.995
SLC26A4	O43511-1.1	D661Y	Pathogenic	0.998
SLC26A4	O43511-1.1	C662A	Pathogenic	0.976
SLC26A4	O43511-1.1	C662D	Pathogenic	0.998
SLC26A4	O43511-1.1	C662E	Pathogenic	0.997
SLC26A4	O43511-1.1	C662F	Pathogenic	0.976
SLC26A4	O43511-1.1	C662G	Pathogenic	0.992
SLC26A4	O43511-1.1	C662H	Pathogenic	0.994
SLC26A4	O43511-1.1	C662I	Pathogenic	0.97
SLC26A4	O43511-1.1	C662K	Pathogenic	0.981
SLC26A4	O43511-1.1	C662L	Pathogenic	0.971
SLC26A4	O43511-1.1	C662M	Pathogenic	0.976
SLC26A4	O43511-1.1	C662N	Pathogenic	0.997
SLC26A4	O43511-1.1	C662P	Pathogenic	0.999
SLC26A4	O43511-1.1	C662Q	Pathogenic	0.994
SLC26A4	O43511-1.1	C662R	Pathogenic	0.966
SLC26A4	O43511-1.1	C662S	Pathogenic	0.989
SLC26A4	O43511-1.1	C662T	Pathogenic	0.993
SLC26A4	O43511-1.1	C662V	Pathogenic	0.99
SLC26A4	O43511-1.1	C662W	Pathogenic	0.905
SLC26A4	O43511-1.1	C662Y	Pathogenic	0.976
SLC26A4	O43511-1.1	G663A	Pathogenic	0.656
SLC26A4	O43511-1.1	G663C	Pathogenic	0.835
SLC26A4	O43511-1.1	G663D	Pathogenic	0.52
SLC26A4	O43511-1.1	G663E	Pathogenic	0.504
SLC26A4	O43511-1.1	G663F	Neutral	0.288
SLC26A4	O43511-1.1	G663H	Neutral	0.451
SLC26A4	O43511-1.1	G663I	Pathogenic	0.571
SLC26A4	O43511-1.1	G663K	Neutral	0.215
SLC26A4	O43511-1.1	G663L	Pathogenic	0.58
SLC26A4	O43511-1.1	G663M	Neutral	0.452
SLC26A4	O43511-1.1	G663N	Neutral	0.315
SLC26A4	O43511-1.1	G663P	Pathogenic	0.699
SLC26A4	O43511-1.1	G663Q	Neutral	0.488
SLC26A4	O43511-1.1	G663R	Neutral	0.132
SLC26A4	O43511-1.1	G663S	Pathogenic	0.617
SLC26A4	O43511-1.1	G663T	Pathogenic	0.708
SLC26A4	O43511-1.1	G663V	Pathogenic	0.662
SLC26A4	O43511-1.1	G663W	Neutral	0.046
SLC26A4	O43511-1.1	G663Y	Neutral	0.298
SLC26A4	O43511-1.1	A664C	Pathogenic	0.894
SLC26A4	O43511-1.1	A664D	Pathogenic	0.959
SLC26A4	O43511-1.1	A664E	Pathogenic	0.843
SLC26A4	O43511-1.1	A664F	Pathogenic	0.731
SLC26A4	O43511-1.1	A664G	Pathogenic	0.906
SLC26A4	O43511-1.1	A664H	Pathogenic	0.906
SLC26A4	O43511-1.1	A664I	Pathogenic	0.689
SLC26A4	O43511-1.1	A664K	Pathogenic	0.592
SLC26A4	O43511-1.1	A664L	Pathogenic	0.697
SLC26A4	O43511-1.1	A664M	Pathogenic	0.734
SLC26A4	O43511-1.1	A664N	Pathogenic	0.952
SLC26A4	O43511-1.1	A664P	Pathogenic	0.94
SLC26A4	O43511-1.1	A664Q	Pathogenic	0.835
SLC26A4	O43511-1.1	A664R	Neutral	0.446
SLC26A4	O43511-1.1	A664S	Pathogenic	0.895
SLC26A4	O43511-1.1	A664T	Pathogenic	0.886
SLC26A4	O43511-1.1	A664V	Pathogenic	0.765
SLC26A4	O43511-1.1	A664W	Pathogenic	0.564
SLC26A4	O43511-1.1	A664Y	Pathogenic	0.741
SLC26A4	O43511-1.1	I665A	Neutral	0.14
SLC26A4	O43511-1.1	I665C	Neutral	0.332
SLC26A4	O43511-1.1	I665D	Pathogenic	0.561
SLC26A4	O43511-1.1	I665E	Pathogenic	0.752
SLC26A4	O43511-1.1	I665F	Pathogenic	0.533
SLC26A4	O43511-1.1	I665G	Neutral	0.332
SLC26A4	O43511-1.1	I665H	Pathogenic	0.86
SLC26A4	O43511-1.1	I665K	Pathogenic	0.76
SLC26A4	O43511-1.1	I665L	Neutral	0.31
SLC26A4	O43511-1.1	I665M	Neutral	0.43
SLC26A4	O43511-1.1	I665N	Pathogenic	0.631
SLC26A4	O43511-1.1	I665P	Pathogenic	0.685
SLC26A4	O43511-1.1	I665Q	Pathogenic	0.817
SLC26A4	O43511-1.1	I665R	Pathogenic	0.637
SLC26A4	O43511-1.1	I665S	Neutral	0.273
SLC26A4	O43511-1.1	I665T	Neutral	0.34
SLC26A4	O43511-1.1	I665V	Neutral	0.073
SLC26A4	O43511-1.1	I665W	Pathogenic	0.689
SLC26A4	O43511-1.1	I665Y	Pathogenic	0.56
SLC26A4	O43511-1.1	S666A	Pathogenic	0.938
SLC26A4	O43511-1.1	S666C	Pathogenic	0.972
SLC26A4	O43511-1.1	S666D	Pathogenic	0.939
SLC26A4	O43511-1.1	S666E	Pathogenic	0.877
SLC26A4	O43511-1.1	S666F	Pathogenic	0.848
SLC26A4	O43511-1.1	S666G	Pathogenic	0.936
SLC26A4	O43511-1.1	S666H	Pathogenic	0.919
SLC26A4	O43511-1.1	S666I	Pathogenic	0.901
SLC26A4	O43511-1.1	S666K	Pathogenic	0.659
SLC26A4	O43511-1.1	S666L	Pathogenic	0.904
SLC26A4	O43511-1.1	S666M	Pathogenic	0.85
SLC26A4	O43511-1.1	S666N	Pathogenic	0.867
SLC26A4	O43511-1.1	S666P	Pathogenic	0.97
SLC26A4	O43511-1.1	S666Q	Pathogenic	0.87
SLC26A4	O43511-1.1	S666R	Pathogenic	0.682
SLC26A4	O43511-1.1	S666T	Pathogenic	0.892
SLC26A4	O43511-1.1	S666V	Pathogenic	0.964
SLC26A4	O43511-1.1	S666W	Pathogenic	0.726
SLC26A4	O43511-1.1	S666Y	Pathogenic	0.854
SLC26A4	O43511-1.1	F667A	Pathogenic	0.984
SLC26A4	O43511-1.1	F667C	Pathogenic	0.995
SLC26A4	O43511-1.1	F667D	Pathogenic	0.996
SLC26A4	O43511-1.1	F667E	Pathogenic	0.998
SLC26A4	O43511-1.1	F667G	Pathogenic	0.979
SLC26A4	O43511-1.1	F667H	Pathogenic	0.997
SLC26A4	O43511-1.1	F667I	Pathogenic	0.997
SLC26A4	O43511-1.1	F667K	Pathogenic	0.999
SLC26A4	O43511-1.1	F667L	Pathogenic	0.997
SLC26A4	O43511-1.1	F667M	Pathogenic	0.997
SLC26A4	O43511-1.1	F667N	Pathogenic	0.997
SLC26A4	O43511-1.1	F667P	Pathogenic	0.999
SLC26A4	O43511-1.1	F667Q	Pathogenic	0.999
SLC26A4	O43511-1.1	F667R	Pathogenic	0.999
SLC26A4	O43511-1.1	F667S	Pathogenic	0.986
SLC26A4	O43511-1.1	F667T	Pathogenic	0.995
SLC26A4	O43511-1.1	F667V	Pathogenic	0.996
SLC26A4	O43511-1.1	F667W	Pathogenic	0.986
SLC26A4	O43511-1.1	F667Y	Pathogenic	0.975
SLC26A4	O43511-1.1	L668A	Pathogenic	0.761
SLC26A4	O43511-1.1	L668C	Pathogenic	0.907
SLC26A4	O43511-1.1	L668D	Pathogenic	0.981
SLC26A4	O43511-1.1	L668E	Pathogenic	0.983
SLC26A4	O43511-1.1	L668F	Pathogenic	0.954
SLC26A4	O43511-1.1	L668G	Pathogenic	0.907
SLC26A4	O43511-1.1	L668H	Pathogenic	0.992
SLC26A4	O43511-1.1	L668I	Pathogenic	0.894
SLC26A4	O43511-1.1	L668K	Pathogenic	0.969
SLC26A4	O43511-1.1	L668M	Pathogenic	0.88
SLC26A4	O43511-1.1	L668N	Pathogenic	0.971
SLC26A4	O43511-1.1	L668P	Pathogenic	0.977
SLC26A4	O43511-1.1	L668Q	Pathogenic	0.978
SLC26A4	O43511-1.1	L668R	Pathogenic	0.945
SLC26A4	O43511-1.1	L668S	Pathogenic	0.88
SLC26A4	O43511-1.1	L668T	Pathogenic	0.91
SLC26A4	O43511-1.1	L668V	Pathogenic	0.861
SLC26A4	O43511-1.1	L668W	Pathogenic	0.952
SLC26A4	O43511-1.1	L668Y	Pathogenic	0.961
SLC26A4	O43511-1.1	D669A	Pathogenic	0.999
SLC26A4	O43511-1.1	D669C	Pathogenic	1.0
SLC26A4	O43511-1.1	D669E	Pathogenic	0.99
SLC26A4	O43511-1.1	D669F	Pathogenic	0.998
SLC26A4	O43511-1.1	D669G	Pathogenic	0.995
SLC26A4	O43511-1.1	D669H	Pathogenic	0.998
SLC26A4	O43511-1.1	D669I	Pathogenic	0.999
SLC26A4	O43511-1.1	D669K	Pathogenic	0.996
SLC26A4	O43511-1.1	D669L	Pathogenic	0.999
SLC26A4	O43511-1.1	D669M	Pathogenic	0.999
SLC26A4	O43511-1.1	D669N	Pathogenic	0.997
SLC26A4	O43511-1.1	D669P	Pathogenic	0.999
SLC26A4	O43511-1.1	D669Q	Pathogenic	0.996
SLC26A4	O43511-1.1	D669R	Pathogenic	0.996
SLC26A4	O43511-1.1	D669S	Pathogenic	0.997
SLC26A4	O43511-1.1	D669T	Pathogenic	0.999
SLC26A4	O43511-1.1	D669V	Pathogenic	0.999
SLC26A4	O43511-1.1	D669W	Pathogenic	0.995
SLC26A4	O43511-1.1	D669Y	Pathogenic	0.998
SLC26A4	O43511-1.1	V670A	Neutral	0.248
SLC26A4	O43511-1.1	V670C	Pathogenic	0.669
SLC26A4	O43511-1.1	V670D	Pathogenic	0.839
SLC26A4	O43511-1.1	V670E	Pathogenic	0.811
SLC26A4	O43511-1.1	V670F	Pathogenic	0.519
SLC26A4	O43511-1.1	V670G	Pathogenic	0.501
SLC26A4	O43511-1.1	V670H	Pathogenic	0.885
SLC26A4	O43511-1.1	V670I	Neutral	0.098
SLC26A4	O43511-1.1	V670K	Pathogenic	0.536
SLC26A4	O43511-1.1	V670L	Neutral	0.313
SLC26A4	O43511-1.1	V670M	Neutral	0.353
SLC26A4	O43511-1.1	V670N	Pathogenic	0.874
SLC26A4	O43511-1.1	V670P	Pathogenic	0.815
SLC26A4	O43511-1.1	V670Q	Pathogenic	0.801
SLC26A4	O43511-1.1	V670R	Pathogenic	0.562
SLC26A4	O43511-1.1	V670S	Pathogenic	0.604
SLC26A4	O43511-1.1	V670T	Pathogenic	0.511
SLC26A4	O43511-1.1	V670W	Pathogenic	0.508
SLC26A4	O43511-1.1	V670Y	Neutral	0.482
SLC26A4	O43511-1.1	V671A	Pathogenic	0.547
SLC26A4	O43511-1.1	V671C	Pathogenic	0.881
SLC26A4	O43511-1.1	V671D	Pathogenic	0.95
SLC26A4	O43511-1.1	V671E	Pathogenic	0.94
SLC26A4	O43511-1.1	V671F	Pathogenic	0.798
SLC26A4	O43511-1.1	V671G	Pathogenic	0.786
SLC26A4	O43511-1.1	V671H	Pathogenic	0.966
SLC26A4	O43511-1.1	V671I	Neutral	0.284
SLC26A4	O43511-1.1	V671K	Pathogenic	0.809
SLC26A4	O43511-1.1	V671L	Pathogenic	0.625
SLC26A4	O43511-1.1	V671M	Pathogenic	0.666
SLC26A4	O43511-1.1	V671N	Pathogenic	0.962
SLC26A4	O43511-1.1	V671P	Pathogenic	0.941
SLC26A4	O43511-1.1	V671Q	Pathogenic	0.936
SLC26A4	O43511-1.1	V671R	Pathogenic	0.825
SLC26A4	O43511-1.1	V671S	Pathogenic	0.848
SLC26A4	O43511-1.1	V671T	Pathogenic	0.793
SLC26A4	O43511-1.1	V671W	Pathogenic	0.791
SLC26A4	O43511-1.1	V671Y	Pathogenic	0.773
SLC26A4	O43511-1.1	G672A	Pathogenic	0.629
SLC26A4	O43511-1.1	G672C	Pathogenic	0.818
SLC26A4	O43511-1.1	G672D	Neutral	0.491
SLC26A4	O43511-1.1	G672E	Neutral	0.475
SLC26A4	O43511-1.1	G672F	Neutral	0.265
SLC26A4	O43511-1.1	G672H	Neutral	0.423
SLC26A4	O43511-1.1	G672I	Pathogenic	0.542
SLC26A4	O43511-1.1	G672K	Neutral	0.197
SLC26A4	O43511-1.1	G672L	Pathogenic	0.552
SLC26A4	O43511-1.1	G672M	Neutral	0.424
SLC26A4	O43511-1.1	G672N	Neutral	0.29
SLC26A4	O43511-1.1	G672P	Pathogenic	0.674
SLC26A4	O43511-1.1	G672Q	Neutral	0.459
SLC26A4	O43511-1.1	G672R	Neutral	0.119
SLC26A4	O43511-1.1	G672S	Pathogenic	0.59
SLC26A4	O43511-1.1	G672T	Pathogenic	0.684
SLC26A4	O43511-1.1	G672V	Pathogenic	0.636
SLC26A4	O43511-1.1	G672W	Neutral	0.041
SLC26A4	O43511-1.1	G672Y	Neutral	0.275
SLC26A4	O43511-1.1	V673A	Neutral	0.192
SLC26A4	O43511-1.1	V673C	Pathogenic	0.593
SLC26A4	O43511-1.1	V673D	Pathogenic	0.79
SLC26A4	O43511-1.1	V673E	Pathogenic	0.755
SLC26A4	O43511-1.1	V673F	Neutral	0.438
SLC26A4	O43511-1.1	V673G	Neutral	0.42
SLC26A4	O43511-1.1	V673H	Pathogenic	0.847
SLC26A4	O43511-1.1	V673I	Neutral	0.072
SLC26A4	O43511-1.1	V673K	Neutral	0.455
SLC26A4	O43511-1.1	V673L	Neutral	0.247
SLC26A4	O43511-1.1	V673M	Neutral	0.282
SLC26A4	O43511-1.1	V673N	Pathogenic	0.834
SLC26A4	O43511-1.1	V673P	Pathogenic	0.76
SLC26A4	O43511-1.1	V673Q	Pathogenic	0.743
SLC26A4	O43511-1.1	V673R	Neutral	0.481
SLC26A4	O43511-1.1	V673S	Pathogenic	0.524
SLC26A4	O43511-1.1	V673T	Neutral	0.429
SLC26A4	O43511-1.1	V673W	Neutral	0.426
SLC26A4	O43511-1.1	V673Y	Neutral	0.402
SLC26A4	O43511-1.1	R674A	Pathogenic	0.82
SLC26A4	O43511-1.1	R674C	Pathogenic	0.971
SLC26A4	O43511-1.1	R674D	Pathogenic	0.976
SLC26A4	O43511-1.1	R674E	Pathogenic	0.956
SLC26A4	O43511-1.1	R674F	Pathogenic	0.996
SLC26A4	O43511-1.1	R674G	Pathogenic	0.813
SLC26A4	O43511-1.1	R674H	Pathogenic	0.96
SLC26A4	O43511-1.1	R674I	Pathogenic	0.993
SLC26A4	O43511-1.1	R674K	Pathogenic	0.952
SLC26A4	O43511-1.1	R674L	Pathogenic	0.986
SLC26A4	O43511-1.1	R674M	Pathogenic	0.977
SLC26A4	O43511-1.1	R674N	Pathogenic	0.922
SLC26A4	O43511-1.1	R674P	Pathogenic	0.957
SLC26A4	O43511-1.1	R674Q	Pathogenic	0.92
SLC26A4	O43511-1.1	R674S	Pathogenic	0.872
SLC26A4	O43511-1.1	R674T	Pathogenic	0.937
SLC26A4	O43511-1.1	R674V	Pathogenic	0.986
SLC26A4	O43511-1.1	R674W	Pathogenic	0.994
SLC26A4	O43511-1.1	R674Y	Pathogenic	0.995
SLC26A4	O43511-1.1	S675A	Neutral	0.312
SLC26A4	O43511-1.1	S675C	Pathogenic	0.507
SLC26A4	O43511-1.1	S675D	Neutral	0.313
SLC26A4	O43511-1.1	S675E	Neutral	0.176
SLC26A4	O43511-1.1	S675F	Neutral	0.142
SLC26A4	O43511-1.1	S675G	Neutral	0.303
SLC26A4	O43511-1.1	S675H	Neutral	0.252
SLC26A4	O43511-1.1	S675I	Neutral	0.213
SLC26A4	O43511-1.1	S675K	Neutral	0.054
SLC26A4	O43511-1.1	S675L	Neutral	0.22
SLC26A4	O43511-1.1	S675M	Neutral	0.144
SLC26A4	O43511-1.1	S675N	Neutral	0.162
SLC26A4	O43511-1.1	S675P	Neutral	0.487
SLC26A4	O43511-1.1	S675Q	Neutral	0.166
SLC26A4	O43511-1.1	S675R	Neutral	0.06
SLC26A4	O43511-1.1	S675T	Neutral	0.197
SLC26A4	O43511-1.1	S675V	Neutral	0.445
SLC26A4	O43511-1.1	S675W	Neutral	0.073
SLC26A4	O43511-1.1	S675Y	Neutral	0.148
SLC26A4	O43511-1.1	L676A	Pathogenic	0.742
SLC26A4	O43511-1.1	L676C	Pathogenic	0.898
SLC26A4	O43511-1.1	L676D	Pathogenic	0.978
SLC26A4	O43511-1.1	L676E	Pathogenic	0.982
SLC26A4	O43511-1.1	L676F	Pathogenic	0.95
SLC26A4	O43511-1.1	L676G	Pathogenic	0.898
SLC26A4	O43511-1.1	L676H	Pathogenic	0.991
SLC26A4	O43511-1.1	L676I	Pathogenic	0.884
SLC26A4	O43511-1.1	L676K	Pathogenic	0.965
SLC26A4	O43511-1.1	L676M	Pathogenic	0.869
SLC26A4	O43511-1.1	L676N	Pathogenic	0.968
SLC26A4	O43511-1.1	L676P	Pathogenic	0.975
SLC26A4	O43511-1.1	L676Q	Pathogenic	0.975
SLC26A4	O43511-1.1	L676R	Pathogenic	0.939
SLC26A4	O43511-1.1	L676S	Pathogenic	0.869
SLC26A4	O43511-1.1	L676T	Pathogenic	0.901
SLC26A4	O43511-1.1	L676V	Pathogenic	0.849
SLC26A4	O43511-1.1	L676W	Pathogenic	0.947
SLC26A4	O43511-1.1	L676Y	Pathogenic	0.957
SLC26A4	O43511-1.1	R677A	Neutral	0.195
SLC26A4	O43511-1.1	R677C	Pathogenic	0.639
SLC26A4	O43511-1.1	R677D	Pathogenic	0.685
SLC26A4	O43511-1.1	R677E	Pathogenic	0.535
SLC26A4	O43511-1.1	R677F	Pathogenic	0.922
SLC26A4	O43511-1.1	R677G	Neutral	0.188
SLC26A4	O43511-1.1	R677H	Pathogenic	0.563
SLC26A4	O43511-1.1	R677I	Pathogenic	0.878
SLC26A4	O43511-1.1	R677K	Pathogenic	0.514
SLC26A4	O43511-1.1	R677L	Pathogenic	0.788
SLC26A4	O43511-1.1	R677M	Pathogenic	0.689
SLC26A4	O43511-1.1	R677N	Neutral	0.387
SLC26A4	O43511-1.1	R677P	Pathogenic	0.539
SLC26A4	O43511-1.1	R677Q	Neutral	0.38
SLC26A4	O43511-1.1	R677S	Neutral	0.266
SLC26A4	O43511-1.1	R677T	Neutral	0.443
SLC26A4	O43511-1.1	R677V	Pathogenic	0.792
SLC26A4	O43511-1.1	R677W	Pathogenic	0.901
SLC26A4	O43511-1.1	R677Y	Pathogenic	0.914
SLC26A4	O43511-1.1	V678A	Neutral	0.004
SLC26A4	O43511-1.1	V678C	Neutral	0.027
SLC26A4	O43511-1.1	V678D	Neutral	0.066
SLC26A4	O43511-1.1	V678E	Neutral	0.055
SLC26A4	O43511-1.1	V678F	Neutral	0.015
SLC26A4	O43511-1.1	V678G	Neutral	0.014
SLC26A4	O43511-1.1	V678H	Neutral	0.095
SLC26A4	O43511-1.1	V678I	Neutral	0.001
SLC26A4	O43511-1.1	V678K	Neutral	0.016
SLC26A4	O43511-1.1	V678L	Neutral	0.006
SLC26A4	O43511-1.1	V678M	Neutral	0.007
SLC26A4	O43511-1.1	V678N	Neutral	0.087
SLC26A4	O43511-1.1	V678P	Neutral	0.057
SLC26A4	O43511-1.1	V678Q	Neutral	0.052
SLC26A4	O43511-1.1	V678R	Neutral	0.017
SLC26A4	O43511-1.1	V678S	Neutral	0.02
SLC26A4	O43511-1.1	V678T	Neutral	0.014
SLC26A4	O43511-1.1	V678W	Neutral	0.014
SLC26A4	O43511-1.1	V678Y	Neutral	0.013
SLC26A4	O43511-1.1	I679A	Neutral	0.348
SLC26A4	O43511-1.1	I679C	Pathogenic	0.62
SLC26A4	O43511-1.1	I679D	Pathogenic	0.808
SLC26A4	O43511-1.1	I679E	Pathogenic	0.909
SLC26A4	O43511-1.1	I679F	Pathogenic	0.79
SLC26A4	O43511-1.1	I679G	Pathogenic	0.62
SLC26A4	O43511-1.1	I679H	Pathogenic	0.953
SLC26A4	O43511-1.1	I679K	Pathogenic	0.912
SLC26A4	O43511-1.1	I679L	Pathogenic	0.596
SLC26A4	O43511-1.1	I679M	Pathogenic	0.712
SLC26A4	O43511-1.1	I679N	Pathogenic	0.849
SLC26A4	O43511-1.1	I679P	Pathogenic	0.877
SLC26A4	O43511-1.1	I679Q	Pathogenic	0.936
SLC26A4	O43511-1.1	I679R	Pathogenic	0.852
SLC26A4	O43511-1.1	I679S	Pathogenic	0.552
SLC26A4	O43511-1.1	I679T	Pathogenic	0.629
SLC26A4	O43511-1.1	I679V	Neutral	0.206
SLC26A4	O43511-1.1	I679W	Pathogenic	0.879
SLC26A4	O43511-1.1	I679Y	Pathogenic	0.807
SLC26A4	O43511-1.1	V680A	Neutral	0.116
SLC26A4	O43511-1.1	V680C	Neutral	0.446
SLC26A4	O43511-1.1	V680D	Pathogenic	0.674
SLC26A4	O43511-1.1	V680E	Pathogenic	0.63
SLC26A4	O43511-1.1	V680F	Neutral	0.301
SLC26A4	O43511-1.1	V680G	Neutral	0.286
SLC26A4	O43511-1.1	V680H	Pathogenic	0.754
SLC26A4	O43511-1.1	V680I	Neutral	0.041
SLC26A4	O43511-1.1	V680K	Neutral	0.315
SLC26A4	O43511-1.1	V680L	Neutral	0.153
SLC26A4	O43511-1.1	V680M	Neutral	0.178
SLC26A4	O43511-1.1	V680N	Pathogenic	0.735
SLC26A4	O43511-1.1	V680P	Pathogenic	0.636
SLC26A4	O43511-1.1	V680Q	Pathogenic	0.615
SLC26A4	O43511-1.1	V680R	Neutral	0.338
SLC26A4	O43511-1.1	V680S	Neutral	0.378
SLC26A4	O43511-1.1	V680T	Neutral	0.293
SLC26A4	O43511-1.1	V680W	Neutral	0.291
SLC26A4	O43511-1.1	V680Y	Neutral	0.27
SLC26A4	O43511-1.1	K681A	Pathogenic	0.674
SLC26A4	O43511-1.1	K681C	Pathogenic	0.938
SLC26A4	O43511-1.1	K681D	Pathogenic	0.902
SLC26A4	O43511-1.1	K681E	Pathogenic	0.831
SLC26A4	O43511-1.1	K681F	Pathogenic	0.99
SLC26A4	O43511-1.1	K681G	Pathogenic	0.665
SLC26A4	O43511-1.1	K681H	Pathogenic	0.957
SLC26A4	O43511-1.1	K681I	Pathogenic	0.984
SLC26A4	O43511-1.1	K681L	Pathogenic	0.97
SLC26A4	O43511-1.1	K681M	Pathogenic	0.95
SLC26A4	O43511-1.1	K681N	Pathogenic	0.844
SLC26A4	O43511-1.1	K681P	Pathogenic	0.833
SLC26A4	O43511-1.1	K681Q	Pathogenic	0.84
SLC26A4	O43511-1.1	K681R	Pathogenic	0.833
SLC26A4	O43511-1.1	K681S	Pathogenic	0.606
SLC26A4	O43511-1.1	K681T	Pathogenic	0.872
SLC26A4	O43511-1.1	K681V	Pathogenic	0.942
SLC26A4	O43511-1.1	K681W	Pathogenic	0.96
SLC26A4	O43511-1.1	K681Y	Pathogenic	0.981
SLC26A4	O43511-1.1	E682A	Pathogenic	0.983
SLC26A4	O43511-1.1	E682C	Pathogenic	0.999
SLC26A4	O43511-1.1	E682D	Pathogenic	0.967
SLC26A4	O43511-1.1	E682F	Pathogenic	0.996
SLC26A4	O43511-1.1	E682G	Pathogenic	0.983
SLC26A4	O43511-1.1	E682H	Pathogenic	0.993
SLC26A4	O43511-1.1	E682I	Pathogenic	0.998
SLC26A4	O43511-1.1	E682K	Pathogenic	0.974
SLC26A4	O43511-1.1	E682L	Pathogenic	0.998
SLC26A4	O43511-1.1	E682M	Pathogenic	0.996
SLC26A4	O43511-1.1	E682N	Pathogenic	0.994
SLC26A4	O43511-1.1	E682P	Pathogenic	0.993
SLC26A4	O43511-1.1	E682Q	Pathogenic	0.979
SLC26A4	O43511-1.1	E682R	Pathogenic	0.977
SLC26A4	O43511-1.1	E682S	Pathogenic	0.978
SLC26A4	O43511-1.1	E682T	Pathogenic	0.995
SLC26A4	O43511-1.1	E682V	Pathogenic	0.998
SLC26A4	O43511-1.1	E682W	Pathogenic	0.985
SLC26A4	O43511-1.1	E682Y	Pathogenic	0.993
SLC26A4	O43511-1.1	F683A	Pathogenic	0.905
SLC26A4	O43511-1.1	F683C	Pathogenic	0.967
SLC26A4	O43511-1.1	F683D	Pathogenic	0.974
SLC26A4	O43511-1.1	F683E	Pathogenic	0.989
SLC26A4	O43511-1.1	F683G	Pathogenic	0.878
SLC26A4	O43511-1.1	F683H	Pathogenic	0.978
SLC26A4	O43511-1.1	F683I	Pathogenic	0.982
SLC26A4	O43511-1.1	F683K	Pathogenic	0.996
SLC26A4	O43511-1.1	F683L	Pathogenic	0.981
SLC26A4	O43511-1.1	F683M	Pathogenic	0.978
SLC26A4	O43511-1.1	F683N	Pathogenic	0.98
SLC26A4	O43511-1.1	F683P	Pathogenic	0.992
SLC26A4	O43511-1.1	F683Q	Pathogenic	0.992
SLC26A4	O43511-1.1	F683R	Pathogenic	0.993
SLC26A4	O43511-1.1	F683S	Pathogenic	0.916
SLC26A4	O43511-1.1	F683T	Pathogenic	0.968
SLC26A4	O43511-1.1	F683V	Pathogenic	0.974
SLC26A4	O43511-1.1	F683W	Pathogenic	0.913
SLC26A4	O43511-1.1	F683Y	Pathogenic	0.859
SLC26A4	O43511-1.1	Q684A	Neutral	0.127
SLC26A4	O43511-1.1	Q684C	Pathogenic	0.517
SLC26A4	O43511-1.1	Q684D	Neutral	0.175
SLC26A4	O43511-1.1	Q684E	Neutral	0.111
SLC26A4	O43511-1.1	Q684F	Pathogenic	0.518
SLC26A4	O43511-1.1	Q684G	Neutral	0.123
SLC26A4	O43511-1.1	Q684H	Neutral	0.351
SLC26A4	O43511-1.1	Q684I	Pathogenic	0.637
SLC26A4	O43511-1.1	Q684K	Neutral	0.096
SLC26A4	O43511-1.1	Q684L	Neutral	0.476
SLC26A4	O43511-1.1	Q684M	Neutral	0.213
SLC26A4	O43511-1.1	Q684N	Neutral	0.221
SLC26A4	O43511-1.1	Q684P	Neutral	0.26
SLC26A4	O43511-1.1	Q684R	Neutral	0.056
SLC26A4	O43511-1.1	Q684S	Neutral	0.098
SLC26A4	O43511-1.1	Q684T	Neutral	0.325
SLC26A4	O43511-1.1	Q684V	Pathogenic	0.534
SLC26A4	O43511-1.1	Q684W	Neutral	0.112
SLC26A4	O43511-1.1	Q684Y	Neutral	0.218
SLC26A4	O43511-1.1	R685A	Pathogenic	0.909
SLC26A4	O43511-1.1	R685C	Pathogenic	0.987
SLC26A4	O43511-1.1	R685D	Pathogenic	0.989
SLC26A4	O43511-1.1	R685E	Pathogenic	0.98
SLC26A4	O43511-1.1	R685F	Pathogenic	0.998
SLC26A4	O43511-1.1	R685G	Pathogenic	0.906
SLC26A4	O43511-1.1	R685H	Pathogenic	0.982
SLC26A4	O43511-1.1	R685I	Pathogenic	0.997
SLC26A4	O43511-1.1	R685K	Pathogenic	0.978
SLC26A4	O43511-1.1	R685L	Pathogenic	0.994
SLC26A4	O43511-1.1	R685M	Pathogenic	0.989
SLC26A4	O43511-1.1	R685N	Pathogenic	0.963
SLC26A4	O43511-1.1	R685P	Pathogenic	0.98
SLC26A4	O43511-1.1	R685Q	Pathogenic	0.962
SLC26A4	O43511-1.1	R685S	Pathogenic	0.938
SLC26A4	O43511-1.1	R685T	Pathogenic	0.971
SLC26A4	O43511-1.1	R685V	Pathogenic	0.994
SLC26A4	O43511-1.1	R685W	Pathogenic	0.997
SLC26A4	O43511-1.1	R685Y	Pathogenic	0.998
SLC26A4	O43511-1.1	I686A	Pathogenic	0.743
SLC26A4	O43511-1.1	I686C	Pathogenic	0.899
SLC26A4	O43511-1.1	I686D	Pathogenic	0.958
SLC26A4	O43511-1.1	I686E	Pathogenic	0.982
SLC26A4	O43511-1.1	I686F	Pathogenic	0.953
SLC26A4	O43511-1.1	I686G	Pathogenic	0.898
SLC26A4	O43511-1.1	I686H	Pathogenic	0.991
SLC26A4	O43511-1.1	I686K	Pathogenic	0.983
SLC26A4	O43511-1.1	I686L	Pathogenic	0.889
SLC26A4	O43511-1.1	I686M	Pathogenic	0.931
SLC26A4	O43511-1.1	I686N	Pathogenic	0.968
SLC26A4	O43511-1.1	I686P	Pathogenic	0.975
SLC26A4	O43511-1.1	I686Q	Pathogenic	0.988
SLC26A4	O43511-1.1	I686R	Pathogenic	0.969
SLC26A4	O43511-1.1	I686S	Pathogenic	0.87
SLC26A4	O43511-1.1	I686T	Pathogenic	0.902
SLC26A4	O43511-1.1	I686V	Pathogenic	0.584
SLC26A4	O43511-1.1	I686W	Pathogenic	0.975
SLC26A4	O43511-1.1	I686Y	Pathogenic	0.958
SLC26A4	O43511-1.1	D687A	Pathogenic	0.849
SLC26A4	O43511-1.1	D687C	Pathogenic	0.953
SLC26A4	O43511-1.1	D687E	Neutral	0.394
SLC26A4	O43511-1.1	D687F	Pathogenic	0.721
SLC26A4	O43511-1.1	D687G	Pathogenic	0.571
SLC26A4	O43511-1.1	D687H	Pathogenic	0.723
SLC26A4	O43511-1.1	D687I	Pathogenic	0.808
SLC26A4	O43511-1.1	D687K	Pathogenic	0.612
SLC26A4	O43511-1.1	D687L	Pathogenic	0.898
SLC26A4	O43511-1.1	D687M	Pathogenic	0.84
SLC26A4	O43511-1.1	D687N	Pathogenic	0.698
SLC26A4	O43511-1.1	D687P	Pathogenic	0.871
SLC26A4	O43511-1.1	D687Q	Pathogenic	0.64
SLC26A4	O43511-1.1	D687R	Pathogenic	0.636
SLC26A4	O43511-1.1	D687S	Pathogenic	0.675
SLC26A4	O43511-1.1	D687T	Pathogenic	0.885
SLC26A4	O43511-1.1	D687V	Pathogenic	0.926
SLC26A4	O43511-1.1	D687W	Pathogenic	0.551
SLC26A4	O43511-1.1	D687Y	Pathogenic	0.73
SLC26A4	O43511-1.1	V688A	Pathogenic	0.839
SLC26A4	O43511-1.1	V688C	Pathogenic	0.97
SLC26A4	O43511-1.1	V688D	Pathogenic	0.988
SLC26A4	O43511-1.1	V688E	Pathogenic	0.985
SLC26A4	O43511-1.1	V688F	Pathogenic	0.945
SLC26A4	O43511-1.1	V688G	Pathogenic	0.941
SLC26A4	O43511-1.1	V688H	Pathogenic	0.992
SLC26A4	O43511-1.1	V688I	Pathogenic	0.632
SLC26A4	O43511-1.1	V688K	Pathogenic	0.948
SLC26A4	O43511-1.1	V688L	Pathogenic	0.878
SLC26A4	O43511-1.1	V688M	Pathogenic	0.896
SLC26A4	O43511-1.1	V688N	Pathogenic	0.991
SLC26A4	O43511-1.1	V688P	Pathogenic	0.986
SLC26A4	O43511-1.1	V688Q	Pathogenic	0.985
SLC26A4	O43511-1.1	V688R	Pathogenic	0.953
SLC26A4	O43511-1.1	V688S	Pathogenic	0.96
SLC26A4	O43511-1.1	V688T	Pathogenic	0.943
SLC26A4	O43511-1.1	V688W	Pathogenic	0.942
SLC26A4	O43511-1.1	V688Y	Pathogenic	0.936
SLC26A4	O43511-1.1	N689A	Neutral	0.468
SLC26A4	O43511-1.1	N689C	Pathogenic	0.762
SLC26A4	O43511-1.1	N689D	Neutral	0.299
SLC26A4	O43511-1.1	N689E	Neutral	0.385
SLC26A4	O43511-1.1	N689F	Neutral	0.388
SLC26A4	O43511-1.1	N689G	Neutral	0.094
SLC26A4	O43511-1.1	N689H	Neutral	0.137
SLC26A4	O43511-1.1	N689I	Pathogenic	0.509
SLC26A4	O43511-1.1	N689K	Neutral	0.145
SLC26A4	O43511-1.1	N689L	Pathogenic	0.519
SLC26A4	O43511-1.1	N689M	Neutral	0.391
SLC26A4	O43511-1.1	N689P	Pathogenic	0.679
SLC26A4	O43511-1.1	N689Q	Neutral	0.305
SLC26A4	O43511-1.1	N689R	Neutral	0.086
SLC26A4	O43511-1.1	N689S	Neutral	0.14
SLC26A4	O43511-1.1	N689T	Neutral	0.418
SLC26A4	O43511-1.1	N689V	Pathogenic	0.754
SLC26A4	O43511-1.1	N689W	Neutral	0.232
SLC26A4	O43511-1.1	N689Y	Neutral	0.249
SLC26A4	O43511-1.1	V690A	Pathogenic	0.818
SLC26A4	O43511-1.1	V690C	Pathogenic	0.965
SLC26A4	O43511-1.1	V690D	Pathogenic	0.986
SLC26A4	O43511-1.1	V690E	Pathogenic	0.983
SLC26A4	O43511-1.1	V690F	Pathogenic	0.936
SLC26A4	O43511-1.1	V690G	Pathogenic	0.932
SLC26A4	O43511-1.1	V690H	Pathogenic	0.991
SLC26A4	O43511-1.1	V690I	Pathogenic	0.596
SLC26A4	O43511-1.1	V690K	Pathogenic	0.94
SLC26A4	O43511-1.1	V690L	Pathogenic	0.861
SLC26A4	O43511-1.1	V690M	Pathogenic	0.881
SLC26A4	O43511-1.1	V690N	Pathogenic	0.99
SLC26A4	O43511-1.1	V690P	Pathogenic	0.984
SLC26A4	O43511-1.1	V690Q	Pathogenic	0.982
SLC26A4	O43511-1.1	V690R	Pathogenic	0.946
SLC26A4	O43511-1.1	V690S	Pathogenic	0.954
SLC26A4	O43511-1.1	V690T	Pathogenic	0.934
SLC26A4	O43511-1.1	V690W	Pathogenic	0.934
SLC26A4	O43511-1.1	V690Y	Pathogenic	0.927
SLC26A4	O43511-1.1	Y691A	Pathogenic	0.989
SLC26A4	O43511-1.1	Y691C	Pathogenic	0.996
SLC26A4	O43511-1.1	Y691D	Pathogenic	0.997
SLC26A4	O43511-1.1	Y691E	Pathogenic	0.998
SLC26A4	O43511-1.1	Y691F	Pathogenic	0.982
SLC26A4	O43511-1.1	Y691G	Pathogenic	0.985
SLC26A4	O43511-1.1	Y691H	Pathogenic	0.981
SLC26A4	O43511-1.1	Y691I	Pathogenic	0.998
SLC26A4	O43511-1.1	Y691K	Pathogenic	0.999
SLC26A4	O43511-1.1	Y691L	Pathogenic	0.998
SLC26A4	O43511-1.1	Y691M	Pathogenic	0.999
SLC26A4	O43511-1.1	Y691N	Pathogenic	0.996
SLC26A4	O43511-1.1	Y691P	Pathogenic	0.998
SLC26A4	O43511-1.1	Y691Q	Pathogenic	0.997
SLC26A4	O43511-1.1	Y691R	Pathogenic	0.999
SLC26A4	O43511-1.1	Y691S	Pathogenic	0.99
SLC26A4	O43511-1.1	Y691T	Pathogenic	0.996
SLC26A4	O43511-1.1	Y691V	Pathogenic	0.997
SLC26A4	O43511-1.1	Y691W	Pathogenic	0.978
SLC26A4	O43511-1.1	F692A	Neutral	0.496
SLC26A4	O43511-1.1	F692C	Pathogenic	0.75
SLC26A4	O43511-1.1	F692D	Pathogenic	0.794
SLC26A4	O43511-1.1	F692E	Pathogenic	0.901
SLC26A4	O43511-1.1	F692G	Neutral	0.427
SLC26A4	O43511-1.1	F692H	Pathogenic	0.821
SLC26A4	O43511-1.1	F692I	Pathogenic	0.849
SLC26A4	O43511-1.1	F692K	Pathogenic	0.963
SLC26A4	O43511-1.1	F692L	Pathogenic	0.845
SLC26A4	O43511-1.1	F692M	Pathogenic	0.82
SLC26A4	O43511-1.1	F692N	Pathogenic	0.837
SLC26A4	O43511-1.1	F692P	Pathogenic	0.929
SLC26A4	O43511-1.1	F692Q	Pathogenic	0.931
SLC26A4	O43511-1.1	F692R	Pathogenic	0.934
SLC26A4	O43511-1.1	F692S	Pathogenic	0.53
SLC26A4	O43511-1.1	F692T	Pathogenic	0.757
SLC26A4	O43511-1.1	F692V	Pathogenic	0.794
SLC26A4	O43511-1.1	F692W	Pathogenic	0.522
SLC26A4	O43511-1.1	F692Y	Neutral	0.388
SLC26A4	O43511-1.1	A693C	Pathogenic	0.84
SLC26A4	O43511-1.1	A693D	Pathogenic	0.935
SLC26A4	O43511-1.1	A693E	Pathogenic	0.771
SLC26A4	O43511-1.1	A693F	Pathogenic	0.63
SLC26A4	O43511-1.1	A693G	Pathogenic	0.858
SLC26A4	O43511-1.1	A693H	Pathogenic	0.858
SLC26A4	O43511-1.1	A693I	Pathogenic	0.58
SLC26A4	O43511-1.1	A693K	Neutral	0.476
SLC26A4	O43511-1.1	A693L	Pathogenic	0.59
SLC26A4	O43511-1.1	A693M	Pathogenic	0.633
SLC26A4	O43511-1.1	A693N	Pathogenic	0.925
SLC26A4	O43511-1.1	A693P	Pathogenic	0.907
SLC26A4	O43511-1.1	A693Q	Pathogenic	0.759
SLC26A4	O43511-1.1	A693R	Neutral	0.334
SLC26A4	O43511-1.1	A693S	Pathogenic	0.842
SLC26A4	O43511-1.1	A693T	Pathogenic	0.829
SLC26A4	O43511-1.1	A693V	Pathogenic	0.67
SLC26A4	O43511-1.1	A693W	Neutral	0.447
SLC26A4	O43511-1.1	A693Y	Pathogenic	0.641
SLC26A4	O43511-1.1	S694A	Pathogenic	0.523
SLC26A4	O43511-1.1	S694C	Pathogenic	0.714
SLC26A4	O43511-1.1	S694D	Pathogenic	0.525
SLC26A4	O43511-1.1	S694E	Neutral	0.34
SLC26A4	O43511-1.1	S694F	Neutral	0.287
SLC26A4	O43511-1.1	S694G	Pathogenic	0.513
SLC26A4	O43511-1.1	S694H	Neutral	0.449
SLC26A4	O43511-1.1	S694I	Neutral	0.396
SLC26A4	O43511-1.1	S694K	Neutral	0.122
SLC26A4	O43511-1.1	S694L	Neutral	0.406
SLC26A4	O43511-1.1	S694M	Neutral	0.289
SLC26A4	O43511-1.1	S694N	Neutral	0.319
SLC26A4	O43511-1.1	S694P	Pathogenic	0.697
SLC26A4	O43511-1.1	S694Q	Neutral	0.326
SLC26A4	O43511-1.1	S694R	Neutral	0.134
SLC26A4	O43511-1.1	S694T	Neutral	0.373
SLC26A4	O43511-1.1	S694V	Pathogenic	0.66
SLC26A4	O43511-1.1	S694W	Neutral	0.16
SLC26A4	O43511-1.1	S694Y	Neutral	0.297
SLC26A4	O43511-1.1	L695A	Neutral	0.009
SLC26A4	O43511-1.1	L695C	Neutral	0.026
SLC26A4	O43511-1.1	L695D	Neutral	0.12
SLC26A4	O43511-1.1	L695E	Neutral	0.138
SLC26A4	O43511-1.1	L695F	Neutral	0.053
SLC26A4	O43511-1.1	L695G	Neutral	0.026
SLC26A4	O43511-1.1	L695H	Neutral	0.244
SLC26A4	O43511-1.1	L695I	Neutral	0.022
SLC26A4	O43511-1.1	L695K	Neutral	0.077
SLC26A4	O43511-1.1	L695M	Neutral	0.019
SLC26A4	O43511-1.1	L695N	Neutral	0.083
SLC26A4	O43511-1.1	L695P	Neutral	0.103
SLC26A4	O43511-1.1	L695Q	Neutral	0.105
SLC26A4	O43511-1.1	L695R	Neutral	0.044
SLC26A4	O43511-1.1	L695S	Neutral	0.019
SLC26A4	O43511-1.1	L695T	Neutral	0.026
SLC26A4	O43511-1.1	L695V	Neutral	0.017
SLC26A4	O43511-1.1	L695W	Neutral	0.051
SLC26A4	O43511-1.1	L695Y	Neutral	0.063
SLC26A4	O43511-1.1	Q696A	Neutral	0.405
SLC26A4	O43511-1.1	Q696C	Pathogenic	0.833
SLC26A4	O43511-1.1	Q696D	Neutral	0.498
SLC26A4	O43511-1.1	Q696E	Neutral	0.368
SLC26A4	O43511-1.1	Q696F	Pathogenic	0.834
SLC26A4	O43511-1.1	Q696G	Neutral	0.395
SLC26A4	O43511-1.1	Q696H	Pathogenic	0.716
SLC26A4	O43511-1.1	Q696I	Pathogenic	0.891
SLC26A4	O43511-1.1	Q696K	Neutral	0.332
SLC26A4	O43511-1.1	Q696L	Pathogenic	0.809
SLC26A4	O43511-1.1	Q696M	Pathogenic	0.557
SLC26A4	O43511-1.1	Q696N	Pathogenic	0.57
SLC26A4	O43511-1.1	Q696P	Pathogenic	0.621
SLC26A4	O43511-1.1	Q696R	Neutral	0.215
SLC26A4	O43511-1.1	Q696S	Neutral	0.336
SLC26A4	O43511-1.1	Q696T	Pathogenic	0.692
SLC26A4	O43511-1.1	Q696V	Pathogenic	0.842
SLC26A4	O43511-1.1	Q696W	Neutral	0.371
SLC26A4	O43511-1.1	Q696Y	Pathogenic	0.566
SLC26A4	O43511-1.1	D697A	Pathogenic	0.96
SLC26A4	O43511-1.1	D697C	Pathogenic	0.989
SLC26A4	O43511-1.1	D697E	Pathogenic	0.737
SLC26A4	O43511-1.1	D697F	Pathogenic	0.918
SLC26A4	O43511-1.1	D697G	Pathogenic	0.852
SLC26A4	O43511-1.1	D697H	Pathogenic	0.918
SLC26A4	O43511-1.1	D697I	Pathogenic	0.948
SLC26A4	O43511-1.1	D697K	Pathogenic	0.872
SLC26A4	O43511-1.1	D697L	Pathogenic	0.974
SLC26A4	O43511-1.1	D697M	Pathogenic	0.958
SLC26A4	O43511-1.1	D697N	Pathogenic	0.909
SLC26A4	O43511-1.1	D697P	Pathogenic	0.967
SLC26A4	O43511-1.1	D697Q	Pathogenic	0.885
SLC26A4	O43511-1.1	D697R	Pathogenic	0.883
SLC26A4	O43511-1.1	D697S	Pathogenic	0.9
SLC26A4	O43511-1.1	D697T	Pathogenic	0.971
SLC26A4	O43511-1.1	D697V	Pathogenic	0.982
SLC26A4	O43511-1.1	D697W	Pathogenic	0.841
SLC26A4	O43511-1.1	D697Y	Pathogenic	0.921
SLC26A4	O43511-1.1	Y698A	Neutral	0.019
SLC26A4	O43511-1.1	Y698C	Neutral	0.056
SLC26A4	O43511-1.1	Y698D	Neutral	0.072
SLC26A4	O43511-1.1	Y698E	Neutral	0.083
SLC26A4	O43511-1.1	Y698F	Neutral	0.012
SLC26A4	O43511-1.1	Y698G	Neutral	0.015
SLC26A4	O43511-1.1	Y698H	Neutral	0.011
SLC26A4	O43511-1.1	Y698I	Neutral	0.107
SLC26A4	O43511-1.1	Y698K	Neutral	0.204
SLC26A4	O43511-1.1	Y698L	Neutral	0.11
SLC26A4	O43511-1.1	Y698M	Neutral	0.129
SLC26A4	O43511-1.1	Y698N	Neutral	0.049
SLC26A4	O43511-1.1	Y698P	Neutral	0.116
SLC26A4	O43511-1.1	Y698Q	Neutral	0.063
SLC26A4	O43511-1.1	Y698R	Neutral	0.196
SLC26A4	O43511-1.1	Y698S	Neutral	0.022
SLC26A4	O43511-1.1	Y698T	Neutral	0.059
SLC26A4	O43511-1.1	Y698V	Neutral	0.06
SLC26A4	O43511-1.1	Y698W	Neutral	0.01
SLC26A4	O43511-1.1	V699A	Neutral	0.091
SLC26A4	O43511-1.1	V699C	Neutral	0.38
SLC26A4	O43511-1.1	V699D	Pathogenic	0.613
SLC26A4	O43511-1.1	V699E	Pathogenic	0.565
SLC26A4	O43511-1.1	V699F	Neutral	0.247
SLC26A4	O43511-1.1	V699G	Neutral	0.234
SLC26A4	O43511-1.1	V699H	Pathogenic	0.701
SLC26A4	O43511-1.1	V699I	Neutral	0.032
SLC26A4	O43511-1.1	V699K	Neutral	0.26
SLC26A4	O43511-1.1	V699L	Neutral	0.121
SLC26A4	O43511-1.1	V699M	Neutral	0.142
SLC26A4	O43511-1.1	V699N	Pathogenic	0.679
SLC26A4	O43511-1.1	V699P	Pathogenic	0.572
SLC26A4	O43511-1.1	V699Q	Pathogenic	0.549
SLC26A4	O43511-1.1	V699R	Neutral	0.281
SLC26A4	O43511-1.1	V699S	Neutral	0.317
SLC26A4	O43511-1.1	V699T	Neutral	0.241
SLC26A4	O43511-1.1	V699W	Neutral	0.239
SLC26A4	O43511-1.1	V699Y	Neutral	0.22
SLC26A4	O43511-1.1	I700A	Neutral	0.329
SLC26A4	O43511-1.1	I700C	Pathogenic	0.6
SLC26A4	O43511-1.1	I700D	Pathogenic	0.794
SLC26A4	O43511-1.1	I700E	Pathogenic	0.901
SLC26A4	O43511-1.1	I700F	Pathogenic	0.775
SLC26A4	O43511-1.1	I700G	Pathogenic	0.599
SLC26A4	O43511-1.1	I700H	Pathogenic	0.949
SLC26A4	O43511-1.1	I700K	Pathogenic	0.905
SLC26A4	O43511-1.1	I700L	Pathogenic	0.575
SLC26A4	O43511-1.1	I700M	Pathogenic	0.694
SLC26A4	O43511-1.1	I700N	Pathogenic	0.838
SLC26A4	O43511-1.1	I700P	Pathogenic	0.867
SLC26A4	O43511-1.1	I700Q	Pathogenic	0.931
SLC26A4	O43511-1.1	I700R	Pathogenic	0.841
SLC26A4	O43511-1.1	I700S	Pathogenic	0.53
SLC26A4	O43511-1.1	I700T	Pathogenic	0.608
SLC26A4	O43511-1.1	I700V	Neutral	0.192
SLC26A4	O43511-1.1	I700W	Pathogenic	0.87
SLC26A4	O43511-1.1	I700Y	Pathogenic	0.793
SLC26A4	O43511-1.1	E701A	Neutral	0.461
SLC26A4	O43511-1.1	E701C	Pathogenic	0.927
SLC26A4	O43511-1.1	E701D	Neutral	0.299
SLC26A4	O43511-1.1	E701F	Pathogenic	0.801
SLC26A4	O43511-1.1	E701G	Neutral	0.451
SLC26A4	O43511-1.1	E701H	Pathogenic	0.669
SLC26A4	O43511-1.1	E701I	Pathogenic	0.868
SLC26A4	O43511-1.1	E701K	Neutral	0.355
SLC26A4	O43511-1.1	E701L	Pathogenic	0.872
SLC26A4	O43511-1.1	E701M	Pathogenic	0.803
SLC26A4	O43511-1.1	E701N	Pathogenic	0.692
SLC26A4	O43511-1.1	E701P	Pathogenic	0.674
SLC26A4	O43511-1.1	E701Q	Neutral	0.408
SLC26A4	O43511-1.1	E701R	Neutral	0.379
SLC26A4	O43511-1.1	E701S	Neutral	0.39
SLC26A4	O43511-1.1	E701T	Pathogenic	0.739
SLC26A4	O43511-1.1	E701V	Pathogenic	0.871
SLC26A4	O43511-1.1	E701W	Neutral	0.488
SLC26A4	O43511-1.1	E701Y	Pathogenic	0.678
SLC26A4	O43511-1.1	K702A	Pathogenic	0.709
SLC26A4	O43511-1.1	K702C	Pathogenic	0.947
SLC26A4	O43511-1.1	K702D	Pathogenic	0.916
SLC26A4	O43511-1.1	K702E	Pathogenic	0.853
SLC26A4	O43511-1.1	K702F	Pathogenic	0.992
SLC26A4	O43511-1.1	K702G	Pathogenic	0.701
SLC26A4	O43511-1.1	K702H	Pathogenic	0.963
SLC26A4	O43511-1.1	K702I	Pathogenic	0.986
SLC26A4	O43511-1.1	K702L	Pathogenic	0.974
SLC26A4	O43511-1.1	K702M	Pathogenic	0.957
SLC26A4	O43511-1.1	K702N	Pathogenic	0.865
SLC26A4	O43511-1.1	K702P	Pathogenic	0.855
SLC26A4	O43511-1.1	K702Q	Pathogenic	0.861
SLC26A4	O43511-1.1	K702R	Pathogenic	0.855
SLC26A4	O43511-1.1	K702S	Pathogenic	0.645
SLC26A4	O43511-1.1	K702T	Pathogenic	0.889
SLC26A4	O43511-1.1	K702V	Pathogenic	0.95
SLC26A4	O43511-1.1	K702W	Pathogenic	0.966
SLC26A4	O43511-1.1	K702Y	Pathogenic	0.984
SLC26A4	O43511-1.1	L703A	Pathogenic	0.814
SLC26A4	O43511-1.1	L703C	Pathogenic	0.931
SLC26A4	O43511-1.1	L703D	Pathogenic	0.986
SLC26A4	O43511-1.1	L703E	Pathogenic	0.988
SLC26A4	O43511-1.1	L703F	Pathogenic	0.966
SLC26A4	O43511-1.1	L703G	Pathogenic	0.931
SLC26A4	O43511-1.1	L703H	Pathogenic	0.994
SLC26A4	O43511-1.1	L703I	Pathogenic	0.921
SLC26A4	O43511-1.1	L703K	Pathogenic	0.977
SLC26A4	O43511-1.1	L703M	Pathogenic	0.91
SLC26A4	O43511-1.1	L703N	Pathogenic	0.979
SLC26A4	O43511-1.1	L703P	Pathogenic	0.983
SLC26A4	O43511-1.1	L703Q	Pathogenic	0.984
SLC26A4	O43511-1.1	L703R	Pathogenic	0.959
SLC26A4	O43511-1.1	L703S	Pathogenic	0.91
SLC26A4	O43511-1.1	L703T	Pathogenic	0.933
SLC26A4	O43511-1.1	L703V	Pathogenic	0.896
SLC26A4	O43511-1.1	L703W	Pathogenic	0.965
SLC26A4	O43511-1.1	L703Y	Pathogenic	0.972
SLC26A4	O43511-1.1	E704A	Pathogenic	0.66
SLC26A4	O43511-1.1	E704C	Pathogenic	0.966
SLC26A4	O43511-1.1	E704D	Neutral	0.492
SLC26A4	O43511-1.1	E704F	Pathogenic	0.901
SLC26A4	O43511-1.1	E704G	Pathogenic	0.651
SLC26A4	O43511-1.1	E704H	Pathogenic	0.821
SLC26A4	O43511-1.1	E704I	Pathogenic	0.937
SLC26A4	O43511-1.1	E704K	Pathogenic	0.554
SLC26A4	O43511-1.1	E704L	Pathogenic	0.939
SLC26A4	O43511-1.1	E704M	Pathogenic	0.902
SLC26A4	O43511-1.1	E704N	Pathogenic	0.835
SLC26A4	O43511-1.1	E704P	Pathogenic	0.824
SLC26A4	O43511-1.1	E704Q	Pathogenic	0.609
SLC26A4	O43511-1.1	E704R	Pathogenic	0.58
SLC26A4	O43511-1.1	E704S	Pathogenic	0.591
SLC26A4	O43511-1.1	E704T	Pathogenic	0.865
SLC26A4	O43511-1.1	E704V	Pathogenic	0.938
SLC26A4	O43511-1.1	E704W	Pathogenic	0.683
SLC26A4	O43511-1.1	E704Y	Pathogenic	0.826
SLC26A4	O43511-1.1	Q705A	Neutral	0.22
SLC26A4	O43511-1.1	Q705C	Pathogenic	0.674
SLC26A4	O43511-1.1	Q705D	Neutral	0.291
SLC26A4	O43511-1.1	Q705E	Neutral	0.194
SLC26A4	O43511-1.1	Q705F	Pathogenic	0.675
SLC26A4	O43511-1.1	Q705G	Neutral	0.213
SLC26A4	O43511-1.1	Q705H	Pathogenic	0.511
SLC26A4	O43511-1.1	Q705I	Pathogenic	0.772
SLC26A4	O43511-1.1	Q705K	Neutral	0.171
SLC26A4	O43511-1.1	Q705L	Pathogenic	0.637
SLC26A4	O43511-1.1	Q705M	Neutral	0.343
SLC26A4	O43511-1.1	Q705N	Neutral	0.355
SLC26A4	O43511-1.1	Q705P	Neutral	0.404
SLC26A4	O43511-1.1	Q705R	Neutral	0.102
SLC26A4	O43511-1.1	Q705S	Neutral	0.174
SLC26A4	O43511-1.1	Q705T	Neutral	0.482
SLC26A4	O43511-1.1	Q705V	Pathogenic	0.689
SLC26A4	O43511-1.1	Q705W	Neutral	0.197
SLC26A4	O43511-1.1	Q705Y	Neutral	0.351
SLC26A4	O43511-1.1	C706A	Pathogenic	0.994
SLC26A4	O43511-1.1	C706D	Pathogenic	0.999
SLC26A4	O43511-1.1	C706E	Pathogenic	0.999
SLC26A4	O43511-1.1	C706F	Pathogenic	0.994
SLC26A4	O43511-1.1	C706G	Pathogenic	0.998
SLC26A4	O43511-1.1	C706H	Pathogenic	0.999
SLC26A4	O43511-1.1	C706I	Pathogenic	0.992
SLC26A4	O43511-1.1	C706K	Pathogenic	0.995
SLC26A4	O43511-1.1	C706L	Pathogenic	0.993
SLC26A4	O43511-1.1	C706M	Pathogenic	0.994
SLC26A4	O43511-1.1	C706N	Pathogenic	0.999
SLC26A4	O43511-1.1	C706P	Pathogenic	1.0
SLC26A4	O43511-1.1	C706Q	Pathogenic	0.999
SLC26A4	O43511-1.1	C706R	Pathogenic	0.991
SLC26A4	O43511-1.1	C706S	Pathogenic	0.997
SLC26A4	O43511-1.1	C706T	Pathogenic	0.998
SLC26A4	O43511-1.1	C706V	Pathogenic	0.997
SLC26A4	O43511-1.1	C706W	Pathogenic	0.974
SLC26A4	O43511-1.1	C706Y	Pathogenic	0.994
SLC26A4	O43511-1.1	G707A	Neutral	0.101
SLC26A4	O43511-1.1	G707C	Neutral	0.23
SLC26A4	O43511-1.1	G707D	Neutral	0.06
SLC26A4	O43511-1.1	G707E	Neutral	0.057
SLC26A4	O43511-1.1	G707F	Neutral	0.023
SLC26A4	O43511-1.1	G707H	Neutral	0.046
SLC26A4	O43511-1.1	G707I	Neutral	0.073
SLC26A4	O43511-1.1	G707K	Neutral	0.016
SLC26A4	O43511-1.1	G707L	Neutral	0.075
SLC26A4	O43511-1.1	G707M	Neutral	0.046
SLC26A4	O43511-1.1	G707N	Neutral	0.026
SLC26A4	O43511-1.1	G707P	Neutral	0.121
SLC26A4	O43511-1.1	G707Q	Neutral	0.053
SLC26A4	O43511-1.1	G707R	Neutral	0.009
SLC26A4	O43511-1.1	G707S	Neutral	0.087
SLC26A4	O43511-1.1	G707T	Neutral	0.125
SLC26A4	O43511-1.1	G707V	Neutral	0.103
SLC26A4	O43511-1.1	G707W	Neutral	0.003
SLC26A4	O43511-1.1	G707Y	Neutral	0.024
SLC26A4	O43511-1.1	F708A	Pathogenic	0.982
SLC26A4	O43511-1.1	F708C	Pathogenic	0.994
SLC26A4	O43511-1.1	F708D	Pathogenic	0.995
SLC26A4	O43511-1.1	F708E	Pathogenic	0.998
SLC26A4	O43511-1.1	F708G	Pathogenic	0.976
SLC26A4	O43511-1.1	F708H	Pathogenic	0.996
SLC26A4	O43511-1.1	F708I	Pathogenic	0.997
SLC26A4	O43511-1.1	F708K	Pathogenic	0.999
SLC26A4	O43511-1.1	F708L	Pathogenic	0.997
SLC26A4	O43511-1.1	F708M	Pathogenic	0.996
SLC26A4	O43511-1.1	F708N	Pathogenic	0.996
SLC26A4	O43511-1.1	F708P	Pathogenic	0.999
SLC26A4	O43511-1.1	F708Q	Pathogenic	0.999
SLC26A4	O43511-1.1	F708R	Pathogenic	0.999
SLC26A4	O43511-1.1	F708S	Pathogenic	0.984
SLC26A4	O43511-1.1	F708T	Pathogenic	0.994
SLC26A4	O43511-1.1	F708V	Pathogenic	0.995
SLC26A4	O43511-1.1	F708W	Pathogenic	0.984
SLC26A4	O43511-1.1	F708Y	Pathogenic	0.972
SLC26A4	O43511-1.1	F709A	Pathogenic	0.977
SLC26A4	O43511-1.1	F709C	Pathogenic	0.992
SLC26A4	O43511-1.1	F709D	Pathogenic	0.994
SLC26A4	O43511-1.1	F709E	Pathogenic	0.997
SLC26A4	O43511-1.1	F709G	Pathogenic	0.97
SLC26A4	O43511-1.1	F709H	Pathogenic	0.995
SLC26A4	O43511-1.1	F709I	Pathogenic	0.996
SLC26A4	O43511-1.1	F709K	Pathogenic	0.999
SLC26A4	O43511-1.1	F709L	Pathogenic	0.996
SLC26A4	O43511-1.1	F709M	Pathogenic	0.995
SLC26A4	O43511-1.1	F709N	Pathogenic	0.996
SLC26A4	O43511-1.1	F709P	Pathogenic	0.998
SLC26A4	O43511-1.1	F709Q	Pathogenic	0.998
SLC26A4	O43511-1.1	F709R	Pathogenic	0.998
SLC26A4	O43511-1.1	F709S	Pathogenic	0.98
SLC26A4	O43511-1.1	F709T	Pathogenic	0.993
SLC26A4	O43511-1.1	F709V	Pathogenic	0.994
SLC26A4	O43511-1.1	F709W	Pathogenic	0.979
SLC26A4	O43511-1.1	F709Y	Pathogenic	0.965
SLC26A4	O43511-1.1	D710A	Pathogenic	0.989
SLC26A4	O43511-1.1	D710C	Pathogenic	0.997
SLC26A4	O43511-1.1	D710E	Pathogenic	0.914
SLC26A4	O43511-1.1	D710F	Pathogenic	0.977
SLC26A4	O43511-1.1	D710G	Pathogenic	0.956
SLC26A4	O43511-1.1	D710H	Pathogenic	0.977
SLC26A4	O43511-1.1	D710I	Pathogenic	0.986
SLC26A4	O43511-1.1	D710K	Pathogenic	0.963
SLC26A4	O43511-1.1	D710L	Pathogenic	0.993
SLC26A4	O43511-1.1	D710M	Pathogenic	0.988
SLC26A4	O43511-1.1	D710N	Pathogenic	0.974
SLC26A4	O43511-1.1	D710P	Pathogenic	0.991
SLC26A4	O43511-1.1	D710Q	Pathogenic	0.967
SLC26A4	O43511-1.1	D710R	Pathogenic	0.966
SLC26A4	O43511-1.1	D710S	Pathogenic	0.971
SLC26A4	O43511-1.1	D710T	Pathogenic	0.992
SLC26A4	O43511-1.1	D710V	Pathogenic	0.995
SLC26A4	O43511-1.1	D710W	Pathogenic	0.952
SLC26A4	O43511-1.1	D710Y	Pathogenic	0.978
SLC26A4	O43511-1.1	D711A	Pathogenic	0.933
SLC26A4	O43511-1.1	D711C	Pathogenic	0.981
SLC26A4	O43511-1.1	D711E	Pathogenic	0.618
SLC26A4	O43511-1.1	D711F	Pathogenic	0.865
SLC26A4	O43511-1.1	D711G	Pathogenic	0.769
SLC26A4	O43511-1.1	D711H	Pathogenic	0.867
SLC26A4	O43511-1.1	D711I	Pathogenic	0.913
SLC26A4	O43511-1.1	D711K	Pathogenic	0.797
SLC26A4	O43511-1.1	D711L	Pathogenic	0.956
SLC26A4	O43511-1.1	D711M	Pathogenic	0.929
SLC26A4	O43511-1.1	D711N	Pathogenic	0.852
SLC26A4	O43511-1.1	D711P	Pathogenic	0.944
SLC26A4	O43511-1.1	D711Q	Pathogenic	0.816
SLC26A4	O43511-1.1	D711R	Pathogenic	0.813
SLC26A4	O43511-1.1	D711S	Pathogenic	0.838
SLC26A4	O43511-1.1	D711T	Pathogenic	0.95
SLC26A4	O43511-1.1	D711V	Pathogenic	0.969
SLC26A4	O43511-1.1	D711W	Pathogenic	0.754
SLC26A4	O43511-1.1	D711Y	Pathogenic	0.871
SLC26A4	O43511-1.1	N712A	Pathogenic	0.572
SLC26A4	O43511-1.1	N712C	Pathogenic	0.83
SLC26A4	O43511-1.1	N712D	Neutral	0.393
SLC26A4	O43511-1.1	N712E	Neutral	0.488
SLC26A4	O43511-1.1	N712F	Neutral	0.491
SLC26A4	O43511-1.1	N712G	Neutral	0.137
SLC26A4	O43511-1.1	N712H	Neutral	0.195
SLC26A4	O43511-1.1	N712I	Pathogenic	0.612
SLC26A4	O43511-1.1	N712K	Neutral	0.205
SLC26A4	O43511-1.1	N712L	Pathogenic	0.622
SLC26A4	O43511-1.1	N712M	Neutral	0.495
SLC26A4	O43511-1.1	N712P	Pathogenic	0.763
SLC26A4	O43511-1.1	N712Q	Neutral	0.4
SLC26A4	O43511-1.1	N712R	Neutral	0.125
SLC26A4	O43511-1.1	N712S	Neutral	0.198
SLC26A4	O43511-1.1	N712T	Pathogenic	0.522
SLC26A4	O43511-1.1	N712V	Pathogenic	0.824
SLC26A4	O43511-1.1	N712W	Neutral	0.315
SLC26A4	O43511-1.1	N712Y	Neutral	0.336
SLC26A4	O43511-1.1	I713A	Neutral	0.225
SLC26A4	O43511-1.1	I713C	Neutral	0.471
SLC26A4	O43511-1.1	I713D	Pathogenic	0.696
SLC26A4	O43511-1.1	I713E	Pathogenic	0.845
SLC26A4	O43511-1.1	I713F	Pathogenic	0.672
SLC26A4	O43511-1.1	I713G	Neutral	0.471
SLC26A4	O43511-1.1	I713H	Pathogenic	0.916
SLC26A4	O43511-1.1	I713K	Pathogenic	0.85
SLC26A4	O43511-1.1	I713L	Neutral	0.446
SLC26A4	O43511-1.1	I713M	Pathogenic	0.574
SLC26A4	O43511-1.1	I713N	Pathogenic	0.754
SLC26A4	O43511-1.1	I713P	Pathogenic	0.795
SLC26A4	O43511-1.1	I713Q	Pathogenic	0.889
SLC26A4	O43511-1.1	I713R	Pathogenic	0.759
SLC26A4	O43511-1.1	I713S	Neutral	0.402
SLC26A4	O43511-1.1	I713T	Neutral	0.48
SLC26A4	O43511-1.1	I713V	Neutral	0.124
SLC26A4	O43511-1.1	I713W	Pathogenic	0.799
SLC26A4	O43511-1.1	I713Y	Pathogenic	0.695
SLC26A4	O43511-1.1	R714A	Neutral	0.158
SLC26A4	O43511-1.1	R714C	Pathogenic	0.579
SLC26A4	O43511-1.1	R714D	Pathogenic	0.627
SLC26A4	O43511-1.1	R714E	Neutral	0.472
SLC26A4	O43511-1.1	R714F	Pathogenic	0.902
SLC26A4	O43511-1.1	R714G	Neutral	0.152
SLC26A4	O43511-1.1	R714H	Neutral	0.499
SLC26A4	O43511-1.1	R714I	Pathogenic	0.848
SLC26A4	O43511-1.1	R714K	Neutral	0.45
SLC26A4	O43511-1.1	R714L	Pathogenic	0.742
SLC26A4	O43511-1.1	R714M	Pathogenic	0.632
SLC26A4	O43511-1.1	R714N	Neutral	0.329
SLC26A4	O43511-1.1	R714P	Neutral	0.475
SLC26A4	O43511-1.1	R714Q	Neutral	0.322
SLC26A4	O43511-1.1	R714S	Neutral	0.219
SLC26A4	O43511-1.1	R714T	Neutral	0.382
SLC26A4	O43511-1.1	R714V	Pathogenic	0.747
SLC26A4	O43511-1.1	R714W	Pathogenic	0.875
SLC26A4	O43511-1.1	R714Y	Pathogenic	0.892
SLC26A4	O43511-1.1	K715A	Neutral	0.058
SLC26A4	O43511-1.1	K715C	Neutral	0.311
SLC26A4	O43511-1.1	K715D	Neutral	0.216
SLC26A4	O43511-1.1	K715E	Neutral	0.127
SLC26A4	O43511-1.1	K715F	Pathogenic	0.751
SLC26A4	O43511-1.1	K715G	Neutral	0.056
SLC26A4	O43511-1.1	K715H	Neutral	0.397
SLC26A4	O43511-1.1	K715I	Pathogenic	0.646
SLC26A4	O43511-1.1	K715L	Neutral	0.486
SLC26A4	O43511-1.1	K715M	Neutral	0.361
SLC26A4	O43511-1.1	K715N	Neutral	0.139
SLC26A4	O43511-1.1	K715P	Neutral	0.129
SLC26A4	O43511-1.1	K715Q	Neutral	0.135
SLC26A4	O43511-1.1	K715R	Neutral	0.13
SLC26A4	O43511-1.1	K715S	Neutral	0.044
SLC26A4	O43511-1.1	K715T	Neutral	0.169
SLC26A4	O43511-1.1	K715V	Neutral	0.326
SLC26A4	O43511-1.1	K715W	Neutral	0.416
SLC26A4	O43511-1.1	K715Y	Pathogenic	0.612
SLC26A4	O43511-1.1	D716A	Pathogenic	0.921
SLC26A4	O43511-1.1	D716C	Pathogenic	0.977
SLC26A4	O43511-1.1	D716E	Pathogenic	0.573
SLC26A4	O43511-1.1	D716F	Pathogenic	0.842
SLC26A4	O43511-1.1	D716G	Pathogenic	0.734
SLC26A4	O43511-1.1	D716H	Pathogenic	0.844
SLC26A4	O43511-1.1	D716I	Pathogenic	0.897
SLC26A4	O43511-1.1	D716K	Pathogenic	0.765
SLC26A4	O43511-1.1	D716L	Pathogenic	0.948
SLC26A4	O43511-1.1	D716M	Pathogenic	0.916
SLC26A4	O43511-1.1	D716N	Pathogenic	0.827
SLC26A4	O43511-1.1	D716P	Pathogenic	0.933
SLC26A4	O43511-1.1	D716Q	Pathogenic	0.786
SLC26A4	O43511-1.1	D716R	Pathogenic	0.783
SLC26A4	O43511-1.1	D716S	Pathogenic	0.811
SLC26A4	O43511-1.1	D716T	Pathogenic	0.941
SLC26A4	O43511-1.1	D716V	Pathogenic	0.963
SLC26A4	O43511-1.1	D716W	Pathogenic	0.717
SLC26A4	O43511-1.1	D716Y	Pathogenic	0.849
SLC26A4	O43511-1.1	T717A	Neutral	0.072
SLC26A4	O43511-1.1	T717C	Neutral	0.22
SLC26A4	O43511-1.1	T717D	Neutral	0.24
SLC26A4	O43511-1.1	T717E	Neutral	0.15
SLC26A4	O43511-1.1	T717F	Neutral	0.079
SLC26A4	O43511-1.1	T717G	Neutral	0.109
SLC26A4	O43511-1.1	T717H	Neutral	0.241
SLC26A4	O43511-1.1	T717I	Neutral	0.065
SLC26A4	O43511-1.1	T717K	Neutral	0.045
SLC26A4	O43511-1.1	T717L	Neutral	0.068
SLC26A4	O43511-1.1	T717M	Neutral	0.08
SLC26A4	O43511-1.1	T717N	Neutral	0.138
SLC26A4	O43511-1.1	T717P	Neutral	0.273
SLC26A4	O43511-1.1	T717Q	Neutral	0.142
SLC26A4	O43511-1.1	T717R	Neutral	0.026
SLC26A4	O43511-1.1	T717S	Neutral	0.044
SLC26A4	O43511-1.1	T717V	Neutral	0.093
SLC26A4	O43511-1.1	T717W	Neutral	0.02
SLC26A4	O43511-1.1	T717Y	Neutral	0.083
SLC26A4	O43511-1.1	F718A	Pathogenic	0.928
SLC26A4	O43511-1.1	F718C	Pathogenic	0.975
SLC26A4	O43511-1.1	F718D	Pathogenic	0.981
SLC26A4	O43511-1.1	F718E	Pathogenic	0.992
SLC26A4	O43511-1.1	F718G	Pathogenic	0.907
SLC26A4	O43511-1.1	F718H	Pathogenic	0.984
SLC26A4	O43511-1.1	F718I	Pathogenic	0.987
SLC26A4	O43511-1.1	F718K	Pathogenic	0.997
SLC26A4	O43511-1.1	F718L	Pathogenic	0.986
SLC26A4	O43511-1.1	F718M	Pathogenic	0.984
SLC26A4	O43511-1.1	F718N	Pathogenic	0.985
SLC26A4	O43511-1.1	F718P	Pathogenic	0.994
SLC26A4	O43511-1.1	F718Q	Pathogenic	0.994
SLC26A4	O43511-1.1	F718R	Pathogenic	0.995
SLC26A4	O43511-1.1	F718S	Pathogenic	0.937
SLC26A4	O43511-1.1	F718T	Pathogenic	0.976
SLC26A4	O43511-1.1	F718V	Pathogenic	0.981
SLC26A4	O43511-1.1	F718W	Pathogenic	0.935
SLC26A4	O43511-1.1	F718Y	Pathogenic	0.893
SLC26A4	O43511-1.1	F719A	Pathogenic	0.975
SLC26A4	O43511-1.1	F719C	Pathogenic	0.992
SLC26A4	O43511-1.1	F719D	Pathogenic	0.994
SLC26A4	O43511-1.1	F719E	Pathogenic	0.997
SLC26A4	O43511-1.1	F719G	Pathogenic	0.968
SLC26A4	O43511-1.1	F719H	Pathogenic	0.995
SLC26A4	O43511-1.1	F719I	Pathogenic	0.996
SLC26A4	O43511-1.1	F719K	Pathogenic	0.999
SLC26A4	O43511-1.1	F719L	Pathogenic	0.995
SLC26A4	O43511-1.1	F719M	Pathogenic	0.995
SLC26A4	O43511-1.1	F719N	Pathogenic	0.995
SLC26A4	O43511-1.1	F719P	Pathogenic	0.998
SLC26A4	O43511-1.1	F719Q	Pathogenic	0.998
SLC26A4	O43511-1.1	F719R	Pathogenic	0.998
SLC26A4	O43511-1.1	F719S	Pathogenic	0.978
SLC26A4	O43511-1.1	F719T	Pathogenic	0.992
SLC26A4	O43511-1.1	F719V	Pathogenic	0.994
SLC26A4	O43511-1.1	F719W	Pathogenic	0.978
SLC26A4	O43511-1.1	F719Y	Pathogenic	0.962
SLC26A4	O43511-1.1	L720A	Pathogenic	0.717
SLC26A4	O43511-1.1	L720C	Pathogenic	0.885
SLC26A4	O43511-1.1	L720D	Pathogenic	0.976
SLC26A4	O43511-1.1	L720E	Pathogenic	0.979
SLC26A4	O43511-1.1	L720F	Pathogenic	0.943
SLC26A4	O43511-1.1	L720G	Pathogenic	0.885
SLC26A4	O43511-1.1	L720H	Pathogenic	0.99
SLC26A4	O43511-1.1	L720I	Pathogenic	0.87
SLC26A4	O43511-1.1	L720K	Pathogenic	0.961
SLC26A4	O43511-1.1	L720M	Pathogenic	0.854
SLC26A4	O43511-1.1	L720N	Pathogenic	0.964
SLC26A4	O43511-1.1	L720P	Pathogenic	0.971
SLC26A4	O43511-1.1	L720Q	Pathogenic	0.972
SLC26A4	O43511-1.1	L720R	Pathogenic	0.931
SLC26A4	O43511-1.1	L720S	Pathogenic	0.854
SLC26A4	O43511-1.1	L720T	Pathogenic	0.889
SLC26A4	O43511-1.1	L720V	Pathogenic	0.832
SLC26A4	O43511-1.1	L720W	Pathogenic	0.941
SLC26A4	O43511-1.1	L720Y	Pathogenic	0.952
SLC26A4	O43511-1.1	T721A	Pathogenic	0.986
SLC26A4	O43511-1.1	T721C	Pathogenic	0.996
SLC26A4	O43511-1.1	T721D	Pathogenic	0.997
SLC26A4	O43511-1.1	T721E	Pathogenic	0.994
SLC26A4	O43511-1.1	T721F	Pathogenic	0.988
SLC26A4	O43511-1.1	T721G	Pathogenic	0.991
SLC26A4	O43511-1.1	T721H	Pathogenic	0.997
SLC26A4	O43511-1.1	T721I	Pathogenic	0.985
SLC26A4	O43511-1.1	T721K	Pathogenic	0.978
SLC26A4	O43511-1.1	T721L	Pathogenic	0.985
SLC26A4	O43511-1.1	T721M	Pathogenic	0.988
SLC26A4	O43511-1.1	T721N	Pathogenic	0.993
SLC26A4	O43511-1.1	T721P	Pathogenic	0.997
SLC26A4	O43511-1.1	T721Q	Pathogenic	0.994
SLC26A4	O43511-1.1	T721R	Pathogenic	0.961
SLC26A4	O43511-1.1	T721S	Pathogenic	0.977
SLC26A4	O43511-1.1	T721V	Pathogenic	0.99
SLC26A4	O43511-1.1	T721W	Pathogenic	0.95
SLC26A4	O43511-1.1	T721Y	Pathogenic	0.988
SLC26A4	O43511-1.1	V722A	Neutral	0.321
SLC26A4	O43511-1.1	V722C	Pathogenic	0.744
SLC26A4	O43511-1.1	V722D	Pathogenic	0.882
SLC26A4	O43511-1.1	V722E	Pathogenic	0.86
SLC26A4	O43511-1.1	V722F	Pathogenic	0.608
SLC26A4	O43511-1.1	V722G	Pathogenic	0.591
SLC26A4	O43511-1.1	V722H	Pathogenic	0.917
SLC26A4	O43511-1.1	V722I	Neutral	0.135
SLC26A4	O43511-1.1	V722K	Pathogenic	0.624
SLC26A4	O43511-1.1	V722L	Neutral	0.395
SLC26A4	O43511-1.1	V722M	Neutral	0.439
SLC26A4	O43511-1.1	V722N	Pathogenic	0.909
SLC26A4	O43511-1.1	V722P	Pathogenic	0.863
SLC26A4	O43511-1.1	V722Q	Pathogenic	0.852
SLC26A4	O43511-1.1	V722R	Pathogenic	0.649
SLC26A4	O43511-1.1	V722S	Pathogenic	0.687
SLC26A4	O43511-1.1	V722T	Pathogenic	0.6
SLC26A4	O43511-1.1	V722W	Pathogenic	0.597
SLC26A4	O43511-1.1	V722Y	Pathogenic	0.572
SLC26A4	O43511-1.1	H723A	Pathogenic	1.0
SLC26A4	O43511-1.1	H723C	Pathogenic	1.0
SLC26A4	O43511-1.1	H723D	Pathogenic	1.0
SLC26A4	O43511-1.1	H723E	Pathogenic	1.0
SLC26A4	O43511-1.1	H723F	Pathogenic	1.0
SLC26A4	O43511-1.1	H723G	Pathogenic	0.999
SLC26A4	O43511-1.1	H723I	Pathogenic	1.0
SLC26A4	O43511-1.1	H723K	Pathogenic	1.0
SLC26A4	O43511-1.1	H723L	Pathogenic	1.0
SLC26A4	O43511-1.1	H723M	Pathogenic	1.0
SLC26A4	O43511-1.1	H723N	Pathogenic	0.999
SLC26A4	O43511-1.1	H723P	Pathogenic	1.0
SLC26A4	O43511-1.1	H723Q	Pathogenic	1.0
SLC26A4	O43511-1.1	H723R	Pathogenic	0.999
SLC26A4	O43511-1.1	H723S	Pathogenic	0.999
SLC26A4	O43511-1.1	H723T	Pathogenic	1.0
SLC26A4	O43511-1.1	H723V	Pathogenic	1.0
SLC26A4	O43511-1.1	H723W	Pathogenic	0.999
SLC26A4	O43511-1.1	H723Y	Pathogenic	0.998
SLC26A4	O43511-1.1	D724A	Pathogenic	0.999
SLC26A4	O43511-1.1	D724C	Pathogenic	1.0
SLC26A4	O43511-1.1	D724E	Pathogenic	0.989
SLC26A4	O43511-1.1	D724F	Pathogenic	0.997
SLC26A4	O43511-1.1	D724G	Pathogenic	0.995
SLC26A4	O43511-1.1	D724H	Pathogenic	0.997
SLC26A4	O43511-1.1	D724I	Pathogenic	0.998
SLC26A4	O43511-1.1	D724K	Pathogenic	0.995
SLC26A4	O43511-1.1	D724L	Pathogenic	0.999
SLC26A4	O43511-1.1	D724M	Pathogenic	0.999
SLC26A4	O43511-1.1	D724N	Pathogenic	0.997
SLC26A4	O43511-1.1	D724P	Pathogenic	0.999
SLC26A4	O43511-1.1	D724Q	Pathogenic	0.996
SLC26A4	O43511-1.1	D724R	Pathogenic	0.996
SLC26A4	O43511-1.1	D724S	Pathogenic	0.997
SLC26A4	O43511-1.1	D724T	Pathogenic	0.999
SLC26A4	O43511-1.1	D724V	Pathogenic	0.999
SLC26A4	O43511-1.1	D724W	Pathogenic	0.994
SLC26A4	O43511-1.1	D724Y	Pathogenic	0.997
SLC26A4	O43511-1.1	A725C	Pathogenic	0.991
SLC26A4	O43511-1.1	A725D	Pathogenic	0.997
SLC26A4	O43511-1.1	A725E	Pathogenic	0.985
SLC26A4	O43511-1.1	A725F	Pathogenic	0.972
SLC26A4	O43511-1.1	A725G	Pathogenic	0.992
SLC26A4	O43511-1.1	A725H	Pathogenic	0.992
SLC26A4	O43511-1.1	A725I	Pathogenic	0.965
SLC26A4	O43511-1.1	A725K	Pathogenic	0.948
SLC26A4	O43511-1.1	A725L	Pathogenic	0.967
SLC26A4	O43511-1.1	A725M	Pathogenic	0.972
SLC26A4	O43511-1.1	A725N	Pathogenic	0.996
SLC26A4	O43511-1.1	A725P	Pathogenic	0.995
SLC26A4	O43511-1.1	A725Q	Pathogenic	0.984
SLC26A4	O43511-1.1	A725R	Pathogenic	0.91
SLC26A4	O43511-1.1	A725S	Pathogenic	0.991
SLC26A4	O43511-1.1	A725T	Pathogenic	0.99
SLC26A4	O43511-1.1	A725V	Pathogenic	0.976
SLC26A4	O43511-1.1	A725W	Pathogenic	0.942
SLC26A4	O43511-1.1	A725Y	Pathogenic	0.973
SLC26A4	O43511-1.1	I726A	Neutral	0.096
SLC26A4	O43511-1.1	I726C	Neutral	0.244
SLC26A4	O43511-1.1	I726D	Neutral	0.454
SLC26A4	O43511-1.1	I726E	Pathogenic	0.664
SLC26A4	O43511-1.1	I726F	Neutral	0.426
SLC26A4	O43511-1.1	I726G	Neutral	0.244
SLC26A4	O43511-1.1	I726H	Pathogenic	0.799
SLC26A4	O43511-1.1	I726K	Pathogenic	0.674
SLC26A4	O43511-1.1	I726L	Neutral	0.226
SLC26A4	O43511-1.1	I726M	Neutral	0.329
SLC26A4	O43511-1.1	I726N	Pathogenic	0.527
SLC26A4	O43511-1.1	I726P	Pathogenic	0.585
SLC26A4	O43511-1.1	I726Q	Pathogenic	0.744
SLC26A4	O43511-1.1	I726R	Pathogenic	0.533
SLC26A4	O43511-1.1	I726S	Neutral	0.196
SLC26A4	O43511-1.1	I726T	Neutral	0.251
SLC26A4	O43511-1.1	I726V	Neutral	0.049
SLC26A4	O43511-1.1	I726W	Pathogenic	0.59
SLC26A4	O43511-1.1	I726Y	Neutral	0.453
SLC26A4	O43511-1.1	L727A	Pathogenic	0.909
SLC26A4	O43511-1.1	L727C	Pathogenic	0.968
SLC26A4	O43511-1.1	L727D	Pathogenic	0.994
SLC26A4	O43511-1.1	L727E	Pathogenic	0.995
SLC26A4	O43511-1.1	L727F	Pathogenic	0.985
SLC26A4	O43511-1.1	L727G	Pathogenic	0.968
SLC26A4	O43511-1.1	L727H	Pathogenic	0.997
SLC26A4	O43511-1.1	L727I	Pathogenic	0.963
SLC26A4	O43511-1.1	L727K	Pathogenic	0.99
SLC26A4	O43511-1.1	L727M	Pathogenic	0.958
SLC26A4	O43511-1.1	L727N	Pathogenic	0.991
SLC26A4	O43511-1.1	L727P	Pathogenic	0.993
SLC26A4	O43511-1.1	L727Q	Pathogenic	0.993
SLC26A4	O43511-1.1	L727R	Pathogenic	0.982
SLC26A4	O43511-1.1	L727S	Pathogenic	0.958
SLC26A4	O43511-1.1	L727T	Pathogenic	0.969
SLC26A4	O43511-1.1	L727V	Pathogenic	0.951
SLC26A4	O43511-1.1	L727W	Pathogenic	0.984
SLC26A4	O43511-1.1	L727Y	Pathogenic	0.987
SLC26A4	O43511-1.1	Y728A	Pathogenic	0.583
SLC26A4	O43511-1.1	Y728C	Pathogenic	0.808
SLC26A4	O43511-1.1	Y728D	Pathogenic	0.845
SLC26A4	O43511-1.1	Y728E	Pathogenic	0.866
SLC26A4	O43511-1.1	Y728F	Neutral	0.462
SLC26A4	O43511-1.1	Y728G	Pathogenic	0.514
SLC26A4	O43511-1.1	Y728H	Neutral	0.445
SLC26A4	O43511-1.1	Y728I	Pathogenic	0.894
SLC26A4	O43511-1.1	Y728K	Pathogenic	0.948
SLC26A4	O43511-1.1	Y728L	Pathogenic	0.898
SLC26A4	O43511-1.1	Y728M	Pathogenic	0.913
SLC26A4	O43511-1.1	Y728N	Pathogenic	0.785
SLC26A4	O43511-1.1	Y728P	Pathogenic	0.903
SLC26A4	O43511-1.1	Y728Q	Pathogenic	0.826
SLC26A4	O43511-1.1	Y728R	Pathogenic	0.945
SLC26A4	O43511-1.1	Y728S	Pathogenic	0.616
SLC26A4	O43511-1.1	Y728T	Pathogenic	0.816
SLC26A4	O43511-1.1	Y728V	Pathogenic	0.818
SLC26A4	O43511-1.1	Y728W	Neutral	0.412
SLC26A4	O43511-1.1	L729A	Neutral	0.049
SLC26A4	O43511-1.1	L729C	Neutral	0.135
SLC26A4	O43511-1.1	L729D	Neutral	0.446
SLC26A4	O43511-1.1	L729E	Neutral	0.488
SLC26A4	O43511-1.1	L729F	Neutral	0.251
SLC26A4	O43511-1.1	L729G	Neutral	0.135
SLC26A4	O43511-1.1	L729H	Pathogenic	0.658
SLC26A4	O43511-1.1	L729I	Neutral	0.119
SLC26A4	O43511-1.1	L729K	Neutral	0.331
SLC26A4	O43511-1.1	L729M	Neutral	0.105
SLC26A4	O43511-1.1	L729N	Neutral	0.349
SLC26A4	O43511-1.1	L729P	Neutral	0.405
SLC26A4	O43511-1.1	L729Q	Neutral	0.411
SLC26A4	O43511-1.1	L729R	Neutral	0.215
SLC26A4	O43511-1.1	L729S	Neutral	0.105
SLC26A4	O43511-1.1	L729T	Neutral	0.139
SLC26A4	O43511-1.1	L729V	Neutral	0.091
SLC26A4	O43511-1.1	L729W	Neutral	0.242
SLC26A4	O43511-1.1	L729Y	Neutral	0.285
SLC26A4	O43511-1.1	Q730A	Neutral	0.478
SLC26A4	O43511-1.1	Q730C	Pathogenic	0.87
SLC26A4	O43511-1.1	Q730D	Pathogenic	0.572
SLC26A4	O43511-1.1	Q730E	Neutral	0.439
SLC26A4	O43511-1.1	Q730F	Pathogenic	0.871
SLC26A4	O43511-1.1	Q730G	Neutral	0.467
SLC26A4	O43511-1.1	Q730H	Pathogenic	0.772
SLC26A4	O43511-1.1	Q730I	Pathogenic	0.917
SLC26A4	O43511-1.1	Q730K	Neutral	0.4
SLC26A4	O43511-1.1	Q730L	Pathogenic	0.851
SLC26A4	O43511-1.1	Q730M	Pathogenic	0.629
SLC26A4	O43511-1.1	Q730N	Pathogenic	0.641
SLC26A4	O43511-1.1	Q730P	Pathogenic	0.688
SLC26A4	O43511-1.1	Q730R	Neutral	0.27
SLC26A4	O43511-1.1	Q730S	Neutral	0.405
SLC26A4	O43511-1.1	Q730T	Pathogenic	0.751
SLC26A4	O43511-1.1	Q730V	Pathogenic	0.878
SLC26A4	O43511-1.1	Q730W	Neutral	0.443
SLC26A4	O43511-1.1	Q730Y	Pathogenic	0.637
SLC26A4	O43511-1.1	N731A	Neutral	0.462
SLC26A4	O43511-1.1	N731C	Pathogenic	0.758
SLC26A4	O43511-1.1	N731D	Neutral	0.294
SLC26A4	O43511-1.1	N731E	Neutral	0.38
SLC26A4	O43511-1.1	N731F	Neutral	0.383
SLC26A4	O43511-1.1	N731G	Neutral	0.092
SLC26A4	O43511-1.1	N731H	Neutral	0.135
SLC26A4	O43511-1.1	N731I	Pathogenic	0.504
SLC26A4	O43511-1.1	N731K	Neutral	0.142
SLC26A4	O43511-1.1	N731L	Pathogenic	0.514
SLC26A4	O43511-1.1	N731M	Neutral	0.386
SLC26A4	O43511-1.1	N731P	Pathogenic	0.674
SLC26A4	O43511-1.1	N731Q	Neutral	0.3
SLC26A4	O43511-1.1	N731R	Neutral	0.084
SLC26A4	O43511-1.1	N731S	Neutral	0.137
SLC26A4	O43511-1.1	N731T	Neutral	0.413
SLC26A4	O43511-1.1	N731V	Pathogenic	0.75
SLC26A4	O43511-1.1	N731W	Neutral	0.228
SLC26A4	O43511-1.1	N731Y	Neutral	0.245
SLC26A4	O43511-1.1	Q732A	Pathogenic	0.655
SLC26A4	O43511-1.1	Q732C	Pathogenic	0.933
SLC26A4	O43511-1.1	Q732D	Pathogenic	0.734
SLC26A4	O43511-1.1	Q732E	Pathogenic	0.619
SLC26A4	O43511-1.1	Q732F	Pathogenic	0.933
SLC26A4	O43511-1.1	Q732G	Pathogenic	0.645
SLC26A4	O43511-1.1	Q732H	Pathogenic	0.876
SLC26A4	O43511-1.1	Q732I	Pathogenic	0.958
SLC26A4	O43511-1.1	Q732K	Pathogenic	0.581
SLC26A4	O43511-1.1	Q732L	Pathogenic	0.922
SLC26A4	O43511-1.1	Q732M	Pathogenic	0.778
SLC26A4	O43511-1.1	Q732N	Pathogenic	0.787
SLC26A4	O43511-1.1	Q732P	Pathogenic	0.821
SLC26A4	O43511-1.1	Q732R	Neutral	0.434
SLC26A4	O43511-1.1	Q732S	Pathogenic	0.586
SLC26A4	O43511-1.1	Q732T	Pathogenic	0.862
SLC26A4	O43511-1.1	Q732V	Pathogenic	0.937
SLC26A4	O43511-1.1	Q732W	Pathogenic	0.622
SLC26A4	O43511-1.1	Q732Y	Pathogenic	0.784
SLC26A4	O43511-1.1	V733A	Neutral	0.02
SLC26A4	O43511-1.1	V733C	Neutral	0.113
SLC26A4	O43511-1.1	V733D	Neutral	0.248
SLC26A4	O43511-1.1	V733E	Neutral	0.213
SLC26A4	O43511-1.1	V733F	Neutral	0.064
SLC26A4	O43511-1.1	V733G	Neutral	0.06
SLC26A4	O43511-1.1	V733H	Neutral	0.328
SLC26A4	O43511-1.1	V733I	Neutral	0.007
SLC26A4	O43511-1.1	V733K	Neutral	0.068
SLC26A4	O43511-1.1	V733L	Neutral	0.028
SLC26A4	O43511-1.1	V733M	Neutral	0.033
SLC26A4	O43511-1.1	V733N	Neutral	0.306
SLC26A4	O43511-1.1	V733P	Neutral	0.218
SLC26A4	O43511-1.1	V733Q	Neutral	0.203
SLC26A4	O43511-1.1	V733R	Neutral	0.075
SLC26A4	O43511-1.1	V733S	Neutral	0.088
SLC26A4	O43511-1.1	V733T	Neutral	0.062
SLC26A4	O43511-1.1	V733W	Neutral	0.061
SLC26A4	O43511-1.1	V733Y	Neutral	0.056
SLC26A4	O43511-1.1	K734A	Neutral	0.03
SLC26A4	O43511-1.1	K734C	Neutral	0.185
SLC26A4	O43511-1.1	K734D	Neutral	0.122
SLC26A4	O43511-1.1	K734E	Neutral	0.069
SLC26A4	O43511-1.1	K734F	Pathogenic	0.604
SLC26A4	O43511-1.1	K734G	Neutral	0.029
SLC26A4	O43511-1.1	K734H	Neutral	0.249
SLC26A4	O43511-1.1	K734I	Neutral	0.48
SLC26A4	O43511-1.1	K734L	Neutral	0.323
SLC26A4	O43511-1.1	K734M	Neutral	0.222
SLC26A4	O43511-1.1	K734N	Neutral	0.075
SLC26A4	O43511-1.1	K734P	Neutral	0.07
SLC26A4	O43511-1.1	K734Q	Neutral	0.073
SLC26A4	O43511-1.1	K734R	Neutral	0.07
SLC26A4	O43511-1.1	K734S	Neutral	0.023
SLC26A4	O43511-1.1	K734T	Neutral	0.093
SLC26A4	O43511-1.1	K734V	Neutral	0.196
SLC26A4	O43511-1.1	K734W	Neutral	0.265
SLC26A4	O43511-1.1	K734Y	Neutral	0.443
SLC26A4	O43511-1.1	S735A	Neutral	0.047
SLC26A4	O43511-1.1	S735C	Neutral	0.101
SLC26A4	O43511-1.1	S735D	Neutral	0.048
SLC26A4	O43511-1.1	S735E	Neutral	0.023
SLC26A4	O43511-1.1	S735F	Neutral	0.018
SLC26A4	O43511-1.1	S735G	Neutral	0.045
SLC26A4	O43511-1.1	S735H	Neutral	0.036
SLC26A4	O43511-1.1	S735I	Neutral	0.029
SLC26A4	O43511-1.1	S735K	Neutral	0.006
SLC26A4	O43511-1.1	S735L	Neutral	0.03
SLC26A4	O43511-1.1	S735M	Neutral	0.018
SLC26A4	O43511-1.1	S735N	Neutral	0.021
SLC26A4	O43511-1.1	S735P	Neutral	0.094
SLC26A4	O43511-1.1	S735Q	Neutral	0.021
SLC26A4	O43511-1.1	S735R	Neutral	0.007
SLC26A4	O43511-1.1	S735T	Neutral	0.026
SLC26A4	O43511-1.1	S735V	Neutral	0.081
SLC26A4	O43511-1.1	S735W	Neutral	0.009
SLC26A4	O43511-1.1	S735Y	Neutral	0.019
SLC26A4	O43511-1.1	Q736A	Neutral	0.082
SLC26A4	O43511-1.1	Q736C	Neutral	0.397
SLC26A4	O43511-1.1	Q736D	Neutral	0.115
SLC26A4	O43511-1.1	Q736E	Neutral	0.071
SLC26A4	O43511-1.1	Q736F	Neutral	0.398
SLC26A4	O43511-1.1	Q736G	Neutral	0.079
SLC26A4	O43511-1.1	Q736H	Neutral	0.249
SLC26A4	O43511-1.1	Q736I	Pathogenic	0.519
SLC26A4	O43511-1.1	Q736K	Neutral	0.061
SLC26A4	O43511-1.1	Q736L	Neutral	0.358
SLC26A4	O43511-1.1	Q736M	Neutral	0.142
SLC26A4	O43511-1.1	Q736N	Neutral	0.149
SLC26A4	O43511-1.1	Q736P	Neutral	0.178
SLC26A4	O43511-1.1	Q736R	Neutral	0.035
SLC26A4	O43511-1.1	Q736S	Neutral	0.063
SLC26A4	O43511-1.1	Q736T	Neutral	0.228
SLC26A4	O43511-1.1	Q736V	Neutral	0.413
SLC26A4	O43511-1.1	Q736W	Neutral	0.072
SLC26A4	O43511-1.1	Q736Y	Neutral	0.147
SLC26A4	O43511-1.1	E737A	Neutral	0.12
SLC26A4	O43511-1.1	E737C	Pathogenic	0.667
SLC26A4	O43511-1.1	E737D	Neutral	0.064
SLC26A4	O43511-1.1	E737F	Neutral	0.39
SLC26A4	O43511-1.1	E737G	Neutral	0.116
SLC26A4	O43511-1.1	E737H	Neutral	0.243
SLC26A4	O43511-1.1	E737I	Pathogenic	0.511
SLC26A4	O43511-1.1	E737K	Neutral	0.08
SLC26A4	O43511-1.1	E737L	Pathogenic	0.521
SLC26A4	O43511-1.1	E737M	Neutral	0.393
SLC26A4	O43511-1.1	E737N	Neutral	0.263
SLC26A4	O43511-1.1	E737P	Neutral	0.247
SLC26A4	O43511-1.1	E737Q	Neutral	0.099
SLC26A4	O43511-1.1	E737R	Neutral	0.088
SLC26A4	O43511-1.1	E737S	Neutral	0.092
SLC26A4	O43511-1.1	E737T	Neutral	0.31
SLC26A4	O43511-1.1	E737V	Pathogenic	0.517
SLC26A4	O43511-1.1	E737W	Neutral	0.131
SLC26A4	O43511-1.1	E737Y	Neutral	0.25
SLC26A4	O43511-1.1	G738A	Neutral	0.015
SLC26A4	O43511-1.1	G738C	Neutral	0.04
SLC26A4	O43511-1.1	G738D	Neutral	0.009
SLC26A4	O43511-1.1	G738E	Neutral	0.008
SLC26A4	O43511-1.1	G738F	Neutral	0.003
SLC26A4	O43511-1.1	G738H	Neutral	0.007
SLC26A4	O43511-1.1	G738I	Neutral	0.011
SLC26A4	O43511-1.1	G738K	Neutral	0.002
SLC26A4	O43511-1.1	G738L	Neutral	0.011
SLC26A4	O43511-1.1	G738M	Neutral	0.007
SLC26A4	O43511-1.1	G738N	Neutral	0.004
SLC26A4	O43511-1.1	G738P	Neutral	0.019
SLC26A4	O43511-1.1	G738Q	Neutral	0.008
SLC26A4	O43511-1.1	G738R	Neutral	0.001
SLC26A4	O43511-1.1	G738S	Neutral	0.013
SLC26A4	O43511-1.1	G738T	Neutral	0.019
SLC26A4	O43511-1.1	G738V	Neutral	0.016
SLC26A4	O43511-1.1	G738W	Neutral	0.0
SLC26A4	O43511-1.1	G738Y	Neutral	0.003
SLC26A4	O43511-1.1	Q739A	Neutral	0.292
SLC26A4	O43511-1.1	Q739C	Pathogenic	0.751
SLC26A4	O43511-1.1	Q739D	Neutral	0.375
SLC26A4	O43511-1.1	Q739E	Neutral	0.261
SLC26A4	O43511-1.1	Q739F	Pathogenic	0.752
SLC26A4	O43511-1.1	Q739G	Neutral	0.283
SLC26A4	O43511-1.1	Q739H	Pathogenic	0.604
SLC26A4	O43511-1.1	Q739I	Pathogenic	0.832
SLC26A4	O43511-1.1	Q739K	Neutral	0.231
SLC26A4	O43511-1.1	Q739L	Pathogenic	0.72
SLC26A4	O43511-1.1	Q739M	Neutral	0.433
SLC26A4	O43511-1.1	Q739N	Neutral	0.445
SLC26A4	O43511-1.1	Q739P	Neutral	0.498
SLC26A4	O43511-1.1	Q739R	Neutral	0.142
SLC26A4	O43511-1.1	Q739S	Neutral	0.235
SLC26A4	O43511-1.1	Q739T	Pathogenic	0.576
SLC26A4	O43511-1.1	Q739V	Pathogenic	0.764
SLC26A4	O43511-1.1	Q739W	Neutral	0.263
SLC26A4	O43511-1.1	Q739Y	Neutral	0.441
SLC26A4	O43511-1.1	G740A	Neutral	0.0
SLC26A4	O43511-1.1	G740C	Neutral	0.0
SLC26A4	O43511-1.1	G740D	Neutral	0.0
SLC26A4	O43511-1.1	G740E	Neutral	0.0
SLC26A4	O43511-1.1	G740F	Neutral	0.0
SLC26A4	O43511-1.1	G740H	Neutral	0.0
SLC26A4	O43511-1.1	G740I	Neutral	0.0
SLC26A4	O43511-1.1	G740K	Neutral	0.0
SLC26A4	O43511-1.1	G740L	Neutral	0.0
SLC26A4	O43511-1.1	G740M	Neutral	0.0
SLC26A4	O43511-1.1	G740N	Neutral	0.0
SLC26A4	O43511-1.1	G740P	Neutral	0.0
SLC26A4	O43511-1.1	G740Q	Neutral	0.0
SLC26A4	O43511-1.1	G740R	Neutral	0.0
SLC26A4	O43511-1.1	G740S	Neutral	0.0
SLC26A4	O43511-1.1	G740T	Neutral	0.0
SLC26A4	O43511-1.1	G740V	Neutral	0.0
SLC26A4	O43511-1.1	G740W	Neutral	0.0
SLC26A4	O43511-1.1	G740Y	Neutral	0.0
SLC26A4	O43511-1.1	S741A	Neutral	0.102
SLC26A4	O43511-1.1	S741C	Neutral	0.206
SLC26A4	O43511-1.1	S741D	Neutral	0.103
SLC26A4	O43511-1.1	S741E	Neutral	0.051
SLC26A4	O43511-1.1	S741F	Neutral	0.04
SLC26A4	O43511-1.1	S741G	Neutral	0.099
SLC26A4	O43511-1.1	S741H	Neutral	0.078
SLC26A4	O43511-1.1	S741I	Neutral	0.064
SLC26A4	O43511-1.1	S741K	Neutral	0.014
SLC26A4	O43511-1.1	S741L	Neutral	0.066
SLC26A4	O43511-1.1	S741M	Neutral	0.041
SLC26A4	O43511-1.1	S741N	Neutral	0.046
SLC26A4	O43511-1.1	S741P	Neutral	0.193
SLC26A4	O43511-1.1	S741Q	Neutral	0.048
SLC26A4	O43511-1.1	S741R	Neutral	0.016
SLC26A4	O43511-1.1	S741T	Neutral	0.058
SLC26A4	O43511-1.1	S741V	Neutral	0.168
SLC26A4	O43511-1.1	S741W	Neutral	0.019
SLC26A4	O43511-1.1	S741Y	Neutral	0.042
SLC26A4	O43511-1.1	I742A	Neutral	0.042
SLC26A4	O43511-1.1	I742C	Neutral	0.119
SLC26A4	O43511-1.1	I742D	Neutral	0.259
SLC26A4	O43511-1.1	I742E	Neutral	0.453
SLC26A4	O43511-1.1	I742F	Neutral	0.238
SLC26A4	O43511-1.1	I742G	Neutral	0.119
SLC26A4	O43511-1.1	I742H	Pathogenic	0.626
SLC26A4	O43511-1.1	I742K	Neutral	0.464
SLC26A4	O43511-1.1	I742L	Neutral	0.109
SLC26A4	O43511-1.1	I742M	Neutral	0.17
SLC26A4	O43511-1.1	I742N	Neutral	0.318
SLC26A4	O43511-1.1	I742P	Neutral	0.372
SLC26A4	O43511-1.1	I742Q	Pathogenic	0.549
SLC26A4	O43511-1.1	I742R	Neutral	0.324
SLC26A4	O43511-1.1	I742S	Neutral	0.093
SLC26A4	O43511-1.1	I742T	Neutral	0.123
SLC26A4	O43511-1.1	I742V	Neutral	0.021
SLC26A4	O43511-1.1	I742W	Neutral	0.377
SLC26A4	O43511-1.1	I742Y	Neutral	0.258
SLC26A4	O43511-1.1	L743A	Neutral	0.01
SLC26A4	O43511-1.1	L743C	Neutral	0.029
SLC26A4	O43511-1.1	L743D	Neutral	0.135
SLC26A4	O43511-1.1	L743E	Neutral	0.155
SLC26A4	O43511-1.1	L743F	Neutral	0.061
SLC26A4	O43511-1.1	L743G	Neutral	0.029
SLC26A4	O43511-1.1	L743H	Neutral	0.271
SLC26A4	O43511-1.1	L743I	Neutral	0.026
SLC26A4	O43511-1.1	L743K	Neutral	0.087
SLC26A4	O43511-1.1	L743M	Neutral	0.022
SLC26A4	O43511-1.1	L743N	Neutral	0.094
SLC26A4	O43511-1.1	L743P	Neutral	0.116
SLC26A4	O43511-1.1	L743Q	Neutral	0.119
SLC26A4	O43511-1.1	L743R	Neutral	0.05
SLC26A4	O43511-1.1	L743S	Neutral	0.022
SLC26A4	O43511-1.1	L743T	Neutral	0.03
SLC26A4	O43511-1.1	L743V	Neutral	0.019
SLC26A4	O43511-1.1	L743W	Neutral	0.058
SLC26A4	O43511-1.1	L743Y	Neutral	0.072
SLC26A4	O43511-1.1	E744A	Neutral	0.292
SLC26A4	O43511-1.1	E744C	Pathogenic	0.859
SLC26A4	O43511-1.1	E744D	Neutral	0.17
SLC26A4	O43511-1.1	E744F	Pathogenic	0.659
SLC26A4	O43511-1.1	E744G	Neutral	0.283
SLC26A4	O43511-1.1	E744H	Neutral	0.493
SLC26A4	O43511-1.1	E744I	Pathogenic	0.76
SLC26A4	O43511-1.1	E744K	Neutral	0.209
SLC26A4	O43511-1.1	E744L	Pathogenic	0.767
SLC26A4	O43511-1.1	E744M	Pathogenic	0.662
SLC26A4	O43511-1.1	E744N	Pathogenic	0.519
SLC26A4	O43511-1.1	E744P	Neutral	0.498
SLC26A4	O43511-1.1	E744Q	Neutral	0.249
SLC26A4	O43511-1.1	E744R	Neutral	0.227
SLC26A4	O43511-1.1	E744S	Neutral	0.235
SLC26A4	O43511-1.1	E744T	Pathogenic	0.576
SLC26A4	O43511-1.1	E744V	Pathogenic	0.764
SLC26A4	O43511-1.1	E744W	Neutral	0.314
SLC26A4	O43511-1.1	E744Y	Pathogenic	0.503
SLC26A4	O43511-1.1	T745A	Neutral	0.177
SLC26A4	O43511-1.1	T745C	Neutral	0.439
SLC26A4	O43511-1.1	T745D	Neutral	0.466
SLC26A4	O43511-1.1	T745E	Neutral	0.328
SLC26A4	O43511-1.1	T745F	Neutral	0.192
SLC26A4	O43511-1.1	T745G	Neutral	0.253
SLC26A4	O43511-1.1	T745H	Neutral	0.468
SLC26A4	O43511-1.1	T745I	Neutral	0.162
SLC26A4	O43511-1.1	T745K	Neutral	0.117
SLC26A4	O43511-1.1	T745L	Neutral	0.167
SLC26A4	O43511-1.1	T745M	Neutral	0.194
SLC26A4	O43511-1.1	T745N	Neutral	0.307
SLC26A4	O43511-1.1	T745P	Pathogenic	0.509
SLC26A4	O43511-1.1	T745Q	Neutral	0.314
SLC26A4	O43511-1.1	T745R	Neutral	0.068
SLC26A4	O43511-1.1	T745S	Neutral	0.113
SLC26A4	O43511-1.1	T745V	Neutral	0.221
SLC26A4	O43511-1.1	T745W	Neutral	0.053
SLC26A4	O43511-1.1	T745Y	Neutral	0.2
SLC26A4	O43511-1.1	I746A	Neutral	0.21
SLC26A4	O43511-1.1	I746C	Neutral	0.449
SLC26A4	O43511-1.1	I746D	Pathogenic	0.677
SLC26A4	O43511-1.1	I746E	Pathogenic	0.832
SLC26A4	O43511-1.1	I746F	Pathogenic	0.651
SLC26A4	O43511-1.1	I746G	Neutral	0.448
SLC26A4	O43511-1.1	I746H	Pathogenic	0.909
SLC26A4	O43511-1.1	I746K	Pathogenic	0.839
SLC26A4	O43511-1.1	I746L	Neutral	0.424
SLC26A4	O43511-1.1	I746M	Pathogenic	0.552
SLC26A4	O43511-1.1	I746N	Pathogenic	0.737
SLC26A4	O43511-1.1	I746P	Pathogenic	0.78
SLC26A4	O43511-1.1	I746Q	Pathogenic	0.88
SLC26A4	O43511-1.1	I746R	Pathogenic	0.742
SLC26A4	O43511-1.1	I746S	Neutral	0.38
SLC26A4	O43511-1.1	I746T	Neutral	0.458
SLC26A4	O43511-1.1	I746V	Neutral	0.114
SLC26A4	O43511-1.1	I746W	Pathogenic	0.784
SLC26A4	O43511-1.1	I746Y	Pathogenic	0.675
SLC26A4	O43511-1.1	T747A	Neutral	0.33
SLC26A4	O43511-1.1	T747C	Pathogenic	0.642
SLC26A4	O43511-1.1	T747D	Pathogenic	0.667
SLC26A4	O43511-1.1	T747E	Pathogenic	0.529
SLC26A4	O43511-1.1	T747F	Neutral	0.353
SLC26A4	O43511-1.1	T747G	Neutral	0.437
SLC26A4	O43511-1.1	T747H	Pathogenic	0.669
SLC26A4	O43511-1.1	T747I	Neutral	0.307
SLC26A4	O43511-1.1	T747K	Neutral	0.232
SLC26A4	O43511-1.1	T747L	Neutral	0.315
SLC26A4	O43511-1.1	T747M	Neutral	0.356
SLC26A4	O43511-1.1	T747N	Pathogenic	0.504
SLC26A4	O43511-1.1	T747P	Pathogenic	0.704
SLC26A4	O43511-1.1	T747Q	Pathogenic	0.512
SLC26A4	O43511-1.1	T747R	Neutral	0.143
SLC26A4	O43511-1.1	T747S	Neutral	0.226
SLC26A4	O43511-1.1	T747V	Neutral	0.395
SLC26A4	O43511-1.1	T747W	Neutral	0.114
SLC26A4	O43511-1.1	T747Y	Neutral	0.364
SLC26A4	O43511-1.1	L748A	Neutral	0.141
SLC26A4	O43511-1.1	L748C	Neutral	0.333
SLC26A4	O43511-1.1	L748D	Pathogenic	0.721
SLC26A4	O43511-1.1	L748E	Pathogenic	0.753
SLC26A4	O43511-1.1	L748F	Pathogenic	0.518
SLC26A4	O43511-1.1	L748G	Neutral	0.333
SLC26A4	O43511-1.1	L748H	Pathogenic	0.86
SLC26A4	O43511-1.1	L748I	Neutral	0.303
SLC26A4	O43511-1.1	L748K	Pathogenic	0.614
SLC26A4	O43511-1.1	L748M	Neutral	0.274
SLC26A4	O43511-1.1	L748N	Pathogenic	0.633
SLC26A4	O43511-1.1	L748P	Pathogenic	0.686
SLC26A4	O43511-1.1	L748Q	Pathogenic	0.691
SLC26A4	O43511-1.1	L748R	Neutral	0.468
SLC26A4	O43511-1.1	L748S	Neutral	0.274
SLC26A4	O43511-1.1	L748T	Neutral	0.342
SLC26A4	O43511-1.1	L748V	Neutral	0.242
SLC26A4	O43511-1.1	L748W	Pathogenic	0.506
SLC26A4	O43511-1.1	L748Y	Pathogenic	0.561
SLC26A4	O43511-1.1	I749A	Neutral	0.019
SLC26A4	O43511-1.1	I749C	Neutral	0.055
SLC26A4	O43511-1.1	I749D	Neutral	0.131
SLC26A4	O43511-1.1	I749E	Neutral	0.264
SLC26A4	O43511-1.1	I749F	Neutral	0.119
SLC26A4	O43511-1.1	I749G	Neutral	0.055
SLC26A4	O43511-1.1	I749H	Neutral	0.42
SLC26A4	O43511-1.1	I749K	Neutral	0.273
SLC26A4	O43511-1.1	I749L	Neutral	0.05
SLC26A4	O43511-1.1	I749M	Neutral	0.082
SLC26A4	O43511-1.1	I749N	Neutral	0.168
SLC26A4	O43511-1.1	I749P	Neutral	0.204
SLC26A4	O43511-1.1	I749Q	Neutral	0.345
SLC26A4	O43511-1.1	I749R	Neutral	0.172
SLC26A4	O43511-1.1	I749S	Neutral	0.042
SLC26A4	O43511-1.1	I749T	Neutral	0.057
SLC26A4	O43511-1.1	I749V	Neutral	0.009
SLC26A4	O43511-1.1	I749W	Neutral	0.207
SLC26A4	O43511-1.1	I749Y	Neutral	0.131
SLC26A4	O43511-1.1	Q750A	Pathogenic	0.809
SLC26A4	O43511-1.1	Q750C	Pathogenic	0.969
SLC26A4	O43511-1.1	Q750D	Pathogenic	0.86
SLC26A4	O43511-1.1	Q750E	Pathogenic	0.784
SLC26A4	O43511-1.1	Q750F	Pathogenic	0.969
SLC26A4	O43511-1.1	Q750G	Pathogenic	0.802
SLC26A4	O43511-1.1	Q750H	Pathogenic	0.94
SLC26A4	O43511-1.1	Q750I	Pathogenic	0.981
SLC26A4	O43511-1.1	Q750K	Pathogenic	0.755
SLC26A4	O43511-1.1	Q750L	Pathogenic	0.963
SLC26A4	O43511-1.1	Q750M	Pathogenic	0.887
SLC26A4	O43511-1.1	Q750N	Pathogenic	0.892
SLC26A4	O43511-1.1	Q750P	Pathogenic	0.911
SLC26A4	O43511-1.1	Q750R	Pathogenic	0.631
SLC26A4	O43511-1.1	Q750S	Pathogenic	0.759
SLC26A4	O43511-1.1	Q750T	Pathogenic	0.933
SLC26A4	O43511-1.1	Q750V	Pathogenic	0.971
SLC26A4	O43511-1.1	Q750W	Pathogenic	0.786
SLC26A4	O43511-1.1	Q750Y	Pathogenic	0.89
SLC26A4	O43511-1.1	D751A	Pathogenic	0.501
SLC26A4	O43511-1.1	D751C	Pathogenic	0.786
SLC26A4	O43511-1.1	D751E	Neutral	0.104
SLC26A4	O43511-1.1	D751F	Neutral	0.316
SLC26A4	O43511-1.1	D751G	Neutral	0.193
SLC26A4	O43511-1.1	D751H	Neutral	0.318
SLC26A4	O43511-1.1	D751I	Neutral	0.43
SLC26A4	O43511-1.1	D751K	Neutral	0.22
SLC26A4	O43511-1.1	D751L	Pathogenic	0.612
SLC26A4	O43511-1.1	D751M	Neutral	0.485
SLC26A4	O43511-1.1	D751N	Neutral	0.293
SLC26A4	O43511-1.1	D751P	Pathogenic	0.546
SLC26A4	O43511-1.1	D751Q	Neutral	0.242
SLC26A4	O43511-1.1	D751R	Neutral	0.238
SLC26A4	O43511-1.1	D751S	Neutral	0.271
SLC26A4	O43511-1.1	D751T	Pathogenic	0.579
SLC26A4	O43511-1.1	D751V	Pathogenic	0.69
SLC26A4	O43511-1.1	D751W	Neutral	0.18
SLC26A4	O43511-1.1	D751Y	Neutral	0.326
SLC26A4	O43511-1.1	C752A	Neutral	0.44
SLC26A4	O43511-1.1	C752D	Pathogenic	0.888
SLC26A4	O43511-1.1	C752E	Pathogenic	0.881
SLC26A4	O43511-1.1	C752F	Neutral	0.437
SLC26A4	O43511-1.1	C752G	Pathogenic	0.705
SLC26A4	O43511-1.1	C752H	Pathogenic	0.768
SLC26A4	O43511-1.1	C752I	Neutral	0.387
SLC26A4	O43511-1.1	C752K	Neutral	0.499
SLC26A4	O43511-1.1	C752L	Neutral	0.396
SLC26A4	O43511-1.1	C752M	Neutral	0.44
SLC26A4	O43511-1.1	C752N	Pathogenic	0.871
SLC26A4	O43511-1.1	C752P	Pathogenic	0.936
SLC26A4	O43511-1.1	C752Q	Pathogenic	0.776
SLC26A4	O43511-1.1	C752R	Neutral	0.355
SLC26A4	O43511-1.1	C752S	Pathogenic	0.644
SLC26A4	O43511-1.1	C752T	Pathogenic	0.726
SLC26A4	O43511-1.1	C752V	Pathogenic	0.651
SLC26A4	O43511-1.1	C752W	Neutral	0.155
SLC26A4	O43511-1.1	C752Y	Neutral	0.445
SLC26A4	O43511-1.1	K753A	Neutral	0.062
SLC26A4	O43511-1.1	K753C	Neutral	0.326
SLC26A4	O43511-1.1	K753D	Neutral	0.228
SLC26A4	O43511-1.1	K753E	Neutral	0.135
SLC26A4	O43511-1.1	K753F	Pathogenic	0.764
SLC26A4	O43511-1.1	K753G	Neutral	0.059
SLC26A4	O43511-1.1	K753H	Neutral	0.413
SLC26A4	O43511-1.1	K753I	Pathogenic	0.662
SLC26A4	O43511-1.1	K753L	Pathogenic	0.503
SLC26A4	O43511-1.1	K753M	Neutral	0.377
SLC26A4	O43511-1.1	K753N	Neutral	0.147
SLC26A4	O43511-1.1	K753P	Neutral	0.137
SLC26A4	O43511-1.1	K753Q	Neutral	0.143
SLC26A4	O43511-1.1	K753R	Neutral	0.137
SLC26A4	O43511-1.1	K753S	Neutral	0.047
SLC26A4	O43511-1.1	K753T	Neutral	0.178
SLC26A4	O43511-1.1	K753V	Neutral	0.341
SLC26A4	O43511-1.1	K753W	Neutral	0.433
SLC26A4	O43511-1.1	K753Y	Pathogenic	0.628
SLC26A4	O43511-1.1	D754A	Neutral	0.301
SLC26A4	O43511-1.1	D754C	Pathogenic	0.611
SLC26A4	O43511-1.1	D754E	Neutral	0.047
SLC26A4	O43511-1.1	D754F	Neutral	0.165
SLC26A4	O43511-1.1	D754G	Neutral	0.093
SLC26A4	O43511-1.1	D754H	Neutral	0.167
SLC26A4	O43511-1.1	D754I	Neutral	0.244
SLC26A4	O43511-1.1	D754K	Neutral	0.108
SLC26A4	O43511-1.1	D754L	Neutral	0.403
SLC26A4	O43511-1.1	D754M	Neutral	0.287
SLC26A4	O43511-1.1	D754N	Neutral	0.151
SLC26A4	O43511-1.1	D754P	Neutral	0.34
SLC26A4	O43511-1.1	D754Q	Neutral	0.12
SLC26A4	O43511-1.1	D754R	Neutral	0.118
SLC26A4	O43511-1.1	D754S	Neutral	0.137
SLC26A4	O43511-1.1	D754T	Neutral	0.371
SLC26A4	O43511-1.1	D754V	Neutral	0.488
SLC26A4	O43511-1.1	D754W	Neutral	0.086
SLC26A4	O43511-1.1	D754Y	Neutral	0.172
SLC26A4	O43511-1.1	T755A	Neutral	0.005
SLC26A4	O43511-1.1	T755C	Neutral	0.018
SLC26A4	O43511-1.1	T755D	Neutral	0.02
SLC26A4	O43511-1.1	T755E	Neutral	0.011
SLC26A4	O43511-1.1	T755F	Neutral	0.006
SLC26A4	O43511-1.1	T755G	Neutral	0.008
SLC26A4	O43511-1.1	T755H	Neutral	0.02
SLC26A4	O43511-1.1	T755I	Neutral	0.004
SLC26A4	O43511-1.1	T755K	Neutral	0.003
SLC26A4	O43511-1.1	T755L	Neutral	0.005
SLC26A4	O43511-1.1	T755M	Neutral	0.006
SLC26A4	O43511-1.1	T755N	Neutral	0.01
SLC26A4	O43511-1.1	T755P	Neutral	0.024
SLC26A4	O43511-1.1	T755Q	Neutral	0.011
SLC26A4	O43511-1.1	T755R	Neutral	0.002
SLC26A4	O43511-1.1	T755S	Neutral	0.003
SLC26A4	O43511-1.1	T755V	Neutral	0.007
SLC26A4	O43511-1.1	T755W	Neutral	0.001
SLC26A4	O43511-1.1	T755Y	Neutral	0.006
SLC26A4	O43511-1.1	L756A	Neutral	0.043
SLC26A4	O43511-1.1	L756C	Neutral	0.122
SLC26A4	O43511-1.1	L756D	Neutral	0.418
SLC26A4	O43511-1.1	L756E	Neutral	0.458
SLC26A4	O43511-1.1	L756F	Neutral	0.229
SLC26A4	O43511-1.1	L756G	Neutral	0.122
SLC26A4	O43511-1.1	L756H	Pathogenic	0.631
SLC26A4	O43511-1.1	L756I	Neutral	0.108
SLC26A4	O43511-1.1	L756K	Neutral	0.306
SLC26A4	O43511-1.1	L756M	Neutral	0.095
SLC26A4	O43511-1.1	L756N	Neutral	0.323
SLC26A4	O43511-1.1	L756P	Neutral	0.377
SLC26A4	O43511-1.1	L756Q	Neutral	0.383
SLC26A4	O43511-1.1	L756R	Neutral	0.196
SLC26A4	O43511-1.1	L756S	Neutral	0.095
SLC26A4	O43511-1.1	L756T	Neutral	0.126
SLC26A4	O43511-1.1	L756V	Neutral	0.081
SLC26A4	O43511-1.1	L756W	Neutral	0.221
SLC26A4	O43511-1.1	L756Y	Neutral	0.262
SLC26A4	O43511-1.1	E757A	Neutral	0.214
SLC26A4	O43511-1.1	E757C	Pathogenic	0.8
SLC26A4	O43511-1.1	E757D	Neutral	0.119
SLC26A4	O43511-1.1	E757F	Pathogenic	0.56
SLC26A4	O43511-1.1	E757G	Neutral	0.207
SLC26A4	O43511-1.1	E757H	Neutral	0.391
SLC26A4	O43511-1.1	E757I	Pathogenic	0.676
SLC26A4	O43511-1.1	E757K	Neutral	0.148
SLC26A4	O43511-1.1	E757L	Pathogenic	0.684
SLC26A4	O43511-1.1	E757M	Pathogenic	0.564
SLC26A4	O43511-1.1	E757N	Neutral	0.415
SLC26A4	O43511-1.1	E757P	Neutral	0.396
SLC26A4	O43511-1.1	E757Q	Neutral	0.179
SLC26A4	O43511-1.1	E757R	Neutral	0.162
SLC26A4	O43511-1.1	E757S	Neutral	0.168
SLC26A4	O43511-1.1	E757T	Neutral	0.472
SLC26A4	O43511-1.1	E757V	Pathogenic	0.681
SLC26A4	O43511-1.1	E757W	Neutral	0.232
SLC26A4	O43511-1.1	E757Y	Neutral	0.4
SLC26A4	O43511-1.1	L758A	Neutral	0.015
SLC26A4	O43511-1.1	L758C	Neutral	0.043
SLC26A4	O43511-1.1	L758D	Neutral	0.19
SLC26A4	O43511-1.1	L758E	Neutral	0.217
SLC26A4	O43511-1.1	L758F	Neutral	0.089
SLC26A4	O43511-1.1	L758G	Neutral	0.043
SLC26A4	O43511-1.1	L758H	Neutral	0.359
SLC26A4	O43511-1.1	L758I	Neutral	0.038
SLC26A4	O43511-1.1	L758K	Neutral	0.126
SLC26A4	O43511-1.1	L758M	Neutral	0.033
SLC26A4	O43511-1.1	L758N	Neutral	0.135
SLC26A4	O43511-1.1	L758P	Neutral	0.165
SLC26A4	O43511-1.1	L758Q	Neutral	0.169
SLC26A4	O43511-1.1	L758R	Neutral	0.074
SLC26A4	O43511-1.1	L758S	Neutral	0.033
SLC26A4	O43511-1.1	L758T	Neutral	0.045
SLC26A4	O43511-1.1	L758V	Neutral	0.028
SLC26A4	O43511-1.1	L758W	Neutral	0.085
SLC26A4	O43511-1.1	L758Y	Neutral	0.104
SLC26A4	O43511-1.1	I759A	Neutral	0.008
SLC26A4	O43511-1.1	I759C	Neutral	0.025
SLC26A4	O43511-1.1	I759D	Neutral	0.062
SLC26A4	O43511-1.1	I759E	Neutral	0.136
SLC26A4	O43511-1.1	I759F	Neutral	0.056
SLC26A4	O43511-1.1	I759G	Neutral	0.025
SLC26A4	O43511-1.1	I759H	Neutral	0.242
SLC26A4	O43511-1.1	I759K	Neutral	0.142
SLC26A4	O43511-1.1	I759L	Neutral	0.023
SLC26A4	O43511-1.1	I759M	Neutral	0.038
SLC26A4	O43511-1.1	I759N	Neutral	0.082
SLC26A4	O43511-1.1	I759P	Neutral	0.101
SLC26A4	O43511-1.1	I759Q	Neutral	0.188
SLC26A4	O43511-1.1	I759R	Neutral	0.084
SLC26A4	O43511-1.1	I759S	Neutral	0.019
SLC26A4	O43511-1.1	I759T	Neutral	0.026
SLC26A4	O43511-1.1	I759V	Neutral	0.004
SLC26A4	O43511-1.1	I759W	Neutral	0.103
SLC26A4	O43511-1.1	I759Y	Neutral	0.062
SLC26A4	O43511-1.1	E760A	Neutral	0.245
SLC26A4	O43511-1.1	E760C	Pathogenic	0.827
SLC26A4	O43511-1.1	E760D	Neutral	0.139
SLC26A4	O43511-1.1	E760F	Pathogenic	0.604
SLC26A4	O43511-1.1	E760G	Neutral	0.237
SLC26A4	O43511-1.1	E760H	Neutral	0.434
SLC26A4	O43511-1.1	E760I	Pathogenic	0.713
SLC26A4	O43511-1.1	E760K	Neutral	0.172
SLC26A4	O43511-1.1	E760L	Pathogenic	0.721
SLC26A4	O43511-1.1	E760M	Pathogenic	0.607
SLC26A4	O43511-1.1	E760N	Neutral	0.459
SLC26A4	O43511-1.1	E760P	Neutral	0.439
SLC26A4	O43511-1.1	E760Q	Neutral	0.207
SLC26A4	O43511-1.1	E760R	Neutral	0.188
SLC26A4	O43511-1.1	E760S	Neutral	0.195
SLC26A4	O43511-1.1	E760T	Pathogenic	0.517
SLC26A4	O43511-1.1	E760V	Pathogenic	0.718
SLC26A4	O43511-1.1	E760W	Neutral	0.265
SLC26A4	O43511-1.1	E760Y	Neutral	0.443
SLC26A4	O43511-1.1	T761A	Neutral	0.032
SLC26A4	O43511-1.1	T761C	Neutral	0.109
SLC26A4	O43511-1.1	T761D	Neutral	0.12
SLC26A4	O43511-1.1	T761E	Neutral	0.071
SLC26A4	O43511-1.1	T761F	Neutral	0.036
SLC26A4	O43511-1.1	T761G	Neutral	0.05
SLC26A4	O43511-1.1	T761H	Neutral	0.121
SLC26A4	O43511-1.1	T761I	Neutral	0.029
SLC26A4	O43511-1.1	T761K	Neutral	0.02
SLC26A4	O43511-1.1	T761L	Neutral	0.03
SLC26A4	O43511-1.1	T761M	Neutral	0.036
SLC26A4	O43511-1.1	T761N	Neutral	0.065
SLC26A4	O43511-1.1	T761P	Neutral	0.139
SLC26A4	O43511-1.1	T761Q	Neutral	0.067
SLC26A4	O43511-1.1	T761R	Neutral	0.011
SLC26A4	O43511-1.1	T761S	Neutral	0.02
SLC26A4	O43511-1.1	T761V	Neutral	0.042
SLC26A4	O43511-1.1	T761W	Neutral	0.009
SLC26A4	O43511-1.1	T761Y	Neutral	0.037
SLC26A4	O43511-1.1	E762A	Neutral	0.232
SLC26A4	O43511-1.1	E762C	Pathogenic	0.817
SLC26A4	O43511-1.1	E762D	Neutral	0.131
SLC26A4	O43511-1.1	E762F	Pathogenic	0.587
SLC26A4	O43511-1.1	E762G	Neutral	0.225
SLC26A4	O43511-1.1	E762H	Neutral	0.417
SLC26A4	O43511-1.1	E762I	Pathogenic	0.699
SLC26A4	O43511-1.1	E762K	Neutral	0.163
SLC26A4	O43511-1.1	E762L	Pathogenic	0.707
SLC26A4	O43511-1.1	E762M	Pathogenic	0.59
SLC26A4	O43511-1.1	E762N	Neutral	0.442
SLC26A4	O43511-1.1	E762P	Neutral	0.422
SLC26A4	O43511-1.1	E762Q	Neutral	0.196
SLC26A4	O43511-1.1	E762R	Neutral	0.177
SLC26A4	O43511-1.1	E762S	Neutral	0.184
SLC26A4	O43511-1.1	E762T	Neutral	0.5
SLC26A4	O43511-1.1	E762V	Pathogenic	0.704
SLC26A4	O43511-1.1	E762W	Neutral	0.252
SLC26A4	O43511-1.1	E762Y	Neutral	0.426
SLC26A4	O43511-1.1	L763A	Neutral	0.006
SLC26A4	O43511-1.1	L763C	Neutral	0.017
SLC26A4	O43511-1.1	L763D	Neutral	0.082
SLC26A4	O43511-1.1	L763E	Neutral	0.096
SLC26A4	O43511-1.1	L763F	Neutral	0.036
SLC26A4	O43511-1.1	L763G	Neutral	0.017
SLC26A4	O43511-1.1	L763H	Neutral	0.176
SLC26A4	O43511-1.1	L763I	Neutral	0.015
SLC26A4	O43511-1.1	L763K	Neutral	0.052
SLC26A4	O43511-1.1	L763M	Neutral	0.013
SLC26A4	O43511-1.1	L763N	Neutral	0.056
SLC26A4	O43511-1.1	L763P	Neutral	0.071
SLC26A4	O43511-1.1	L763Q	Neutral	0.072
SLC26A4	O43511-1.1	L763R	Neutral	0.03
SLC26A4	O43511-1.1	L763S	Neutral	0.013
SLC26A4	O43511-1.1	L763T	Neutral	0.018
SLC26A4	O43511-1.1	L763V	Neutral	0.011
SLC26A4	O43511-1.1	L763W	Neutral	0.034
SLC26A4	O43511-1.1	L763Y	Neutral	0.043
SLC26A4	O43511-1.1	T764A	Neutral	0.158
SLC26A4	O43511-1.1	T764C	Neutral	0.406
SLC26A4	O43511-1.1	T764D	Neutral	0.433
SLC26A4	O43511-1.1	T764E	Neutral	0.299
SLC26A4	O43511-1.1	T764F	Neutral	0.172
SLC26A4	O43511-1.1	T764G	Neutral	0.228
SLC26A4	O43511-1.1	T764H	Neutral	0.434
SLC26A4	O43511-1.1	T764I	Neutral	0.144
SLC26A4	O43511-1.1	T764K	Neutral	0.103
SLC26A4	O43511-1.1	T764L	Neutral	0.149
SLC26A4	O43511-1.1	T764M	Neutral	0.174
SLC26A4	O43511-1.1	T764N	Neutral	0.279
SLC26A4	O43511-1.1	T764P	Neutral	0.475
SLC26A4	O43511-1.1	T764Q	Neutral	0.286
SLC26A4	O43511-1.1	T764R	Neutral	0.06
SLC26A4	O43511-1.1	T764S	Neutral	0.1
SLC26A4	O43511-1.1	T764V	Neutral	0.199
SLC26A4	O43511-1.1	T764W	Neutral	0.047
SLC26A4	O43511-1.1	T764Y	Neutral	0.179
SLC26A4	O43511-1.1	E765A	Neutral	0.058
SLC26A4	O43511-1.1	E765C	Neutral	0.474
SLC26A4	O43511-1.1	E765D	Neutral	0.03
SLC26A4	O43511-1.1	E765F	Neutral	0.223
SLC26A4	O43511-1.1	E765G	Neutral	0.056
SLC26A4	O43511-1.1	E765H	Neutral	0.126
SLC26A4	O43511-1.1	E765I	Neutral	0.32
SLC26A4	O43511-1.1	E765K	Neutral	0.038
SLC26A4	O43511-1.1	E765L	Neutral	0.328
SLC26A4	O43511-1.1	E765M	Neutral	0.226
SLC26A4	O43511-1.1	E765N	Neutral	0.138
SLC26A4	O43511-1.1	E765P	Neutral	0.129
SLC26A4	O43511-1.1	E765Q	Neutral	0.047
SLC26A4	O43511-1.1	E765R	Neutral	0.042
SLC26A4	O43511-1.1	E765S	Neutral	0.044
SLC26A4	O43511-1.1	E765T	Neutral	0.168
SLC26A4	O43511-1.1	E765V	Neutral	0.325
SLC26A4	O43511-1.1	E765W	Neutral	0.064
SLC26A4	O43511-1.1	E765Y	Neutral	0.131
SLC26A4	O43511-1.1	E766A	Neutral	0.112
SLC26A4	O43511-1.1	E766C	Pathogenic	0.651
SLC26A4	O43511-1.1	E766D	Neutral	0.059
SLC26A4	O43511-1.1	E766F	Neutral	0.372
SLC26A4	O43511-1.1	E766G	Neutral	0.108
SLC26A4	O43511-1.1	E766H	Neutral	0.23
SLC26A4	O43511-1.1	E766I	Neutral	0.492
SLC26A4	O43511-1.1	E766K	Neutral	0.075
SLC26A4	O43511-1.1	E766L	Pathogenic	0.502
SLC26A4	O43511-1.1	E766M	Neutral	0.376
SLC26A4	O43511-1.1	E766N	Neutral	0.249
SLC26A4	O43511-1.1	E766P	Neutral	0.234
SLC26A4	O43511-1.1	E766Q	Neutral	0.092
SLC26A4	O43511-1.1	E766R	Neutral	0.083
SLC26A4	O43511-1.1	E766S	Neutral	0.086
SLC26A4	O43511-1.1	E766T	Neutral	0.294
SLC26A4	O43511-1.1	E766V	Neutral	0.499
SLC26A4	O43511-1.1	E766W	Neutral	0.123
SLC26A4	O43511-1.1	E766Y	Neutral	0.237
SLC26A4	O43511-1.1	E767A	Neutral	0.344
SLC26A4	O43511-1.1	E767C	Pathogenic	0.885
SLC26A4	O43511-1.1	E767D	Neutral	0.207
SLC26A4	O43511-1.1	E767F	Pathogenic	0.711
SLC26A4	O43511-1.1	E767G	Neutral	0.335
SLC26A4	O43511-1.1	E767H	Pathogenic	0.553
SLC26A4	O43511-1.1	E767I	Pathogenic	0.801
SLC26A4	O43511-1.1	E767K	Neutral	0.252
SLC26A4	O43511-1.1	E767L	Pathogenic	0.807
SLC26A4	O43511-1.1	E767M	Pathogenic	0.714
SLC26A4	O43511-1.1	E767N	Pathogenic	0.578
SLC26A4	O43511-1.1	E767P	Pathogenic	0.558
SLC26A4	O43511-1.1	E767Q	Neutral	0.296
SLC26A4	O43511-1.1	E767R	Neutral	0.272
SLC26A4	O43511-1.1	E767S	Neutral	0.281
SLC26A4	O43511-1.1	E767T	Pathogenic	0.634
SLC26A4	O43511-1.1	E767V	Pathogenic	0.805
SLC26A4	O43511-1.1	E767W	Neutral	0.368
SLC26A4	O43511-1.1	E767Y	Pathogenic	0.563
SLC26A4	O43511-1.1	L768A	Pathogenic	0.739
SLC26A4	O43511-1.1	L768C	Pathogenic	0.897
SLC26A4	O43511-1.1	L768D	Pathogenic	0.978
SLC26A4	O43511-1.1	L768E	Pathogenic	0.981
SLC26A4	O43511-1.1	L768F	Pathogenic	0.949
SLC26A4	O43511-1.1	L768G	Pathogenic	0.896
SLC26A4	O43511-1.1	L768H	Pathogenic	0.991
SLC26A4	O43511-1.1	L768I	Pathogenic	0.883
SLC26A4	O43511-1.1	L768K	Pathogenic	0.965
SLC26A4	O43511-1.1	L768M	Pathogenic	0.867
SLC26A4	O43511-1.1	L768N	Pathogenic	0.968
SLC26A4	O43511-1.1	L768P	Pathogenic	0.974
SLC26A4	O43511-1.1	L768Q	Pathogenic	0.975
SLC26A4	O43511-1.1	L768R	Pathogenic	0.938
SLC26A4	O43511-1.1	L768S	Pathogenic	0.867
SLC26A4	O43511-1.1	L768T	Pathogenic	0.9
SLC26A4	O43511-1.1	L768V	Pathogenic	0.847
SLC26A4	O43511-1.1	L768W	Pathogenic	0.947
SLC26A4	O43511-1.1	L768Y	Pathogenic	0.957
SLC26A4	O43511-1.1	D769A	Pathogenic	0.822
SLC26A4	O43511-1.1	D769C	Pathogenic	0.944
SLC26A4	O43511-1.1	D769E	Neutral	0.349
SLC26A4	O43511-1.1	D769F	Pathogenic	0.68
SLC26A4	O43511-1.1	D769G	Pathogenic	0.524
SLC26A4	O43511-1.1	D769H	Pathogenic	0.683
SLC26A4	O43511-1.1	D769I	Pathogenic	0.777
SLC26A4	O43511-1.1	D769K	Pathogenic	0.565
SLC26A4	O43511-1.1	D769L	Pathogenic	0.879
SLC26A4	O43511-1.1	D769M	Pathogenic	0.812
SLC26A4	O43511-1.1	D769N	Pathogenic	0.656
SLC26A4	O43511-1.1	D769P	Pathogenic	0.847
SLC26A4	O43511-1.1	D769Q	Pathogenic	0.595
SLC26A4	O43511-1.1	D769R	Pathogenic	0.591
SLC26A4	O43511-1.1	D769S	Pathogenic	0.632
SLC26A4	O43511-1.1	D769T	Pathogenic	0.864
SLC26A4	O43511-1.1	D769V	Pathogenic	0.911
SLC26A4	O43511-1.1	D769W	Pathogenic	0.503
SLC26A4	O43511-1.1	D769Y	Pathogenic	0.691
SLC26A4	O43511-1.1	V770A	Neutral	0.073
SLC26A4	O43511-1.1	V770C	Neutral	0.326
SLC26A4	O43511-1.1	V770D	Pathogenic	0.554
SLC26A4	O43511-1.1	V770E	Pathogenic	0.505
SLC26A4	O43511-1.1	V770F	Neutral	0.205
SLC26A4	O43511-1.1	V770G	Neutral	0.194
SLC26A4	O43511-1.1	V770H	Pathogenic	0.648
SLC26A4	O43511-1.1	V770I	Neutral	0.025
SLC26A4	O43511-1.1	V770K	Neutral	0.216
SLC26A4	O43511-1.1	V770L	Neutral	0.098
SLC26A4	O43511-1.1	V770M	Neutral	0.115
SLC26A4	O43511-1.1	V770N	Pathogenic	0.624
SLC26A4	O43511-1.1	V770P	Pathogenic	0.512
SLC26A4	O43511-1.1	V770Q	Neutral	0.489
SLC26A4	O43511-1.1	V770R	Neutral	0.235
SLC26A4	O43511-1.1	V770S	Neutral	0.267
SLC26A4	O43511-1.1	V770T	Neutral	0.199
SLC26A4	O43511-1.1	V770W	Neutral	0.198
SLC26A4	O43511-1.1	V770Y	Neutral	0.182
SLC26A4	O43511-1.1	Q771A	Pathogenic	0.629
SLC26A4	O43511-1.1	Q771C	Pathogenic	0.926
SLC26A4	O43511-1.1	Q771D	Pathogenic	0.712
SLC26A4	O43511-1.1	Q771E	Pathogenic	0.592
SLC26A4	O43511-1.1	Q771F	Pathogenic	0.926
SLC26A4	O43511-1.1	Q771G	Pathogenic	0.62
SLC26A4	O43511-1.1	Q771H	Pathogenic	0.863
SLC26A4	O43511-1.1	Q771I	Pathogenic	0.953
SLC26A4	O43511-1.1	Q771K	Pathogenic	0.553
SLC26A4	O43511-1.1	Q771L	Pathogenic	0.914
SLC26A4	O43511-1.1	Q771M	Pathogenic	0.759
SLC26A4	O43511-1.1	Q771N	Pathogenic	0.768
SLC26A4	O43511-1.1	Q771P	Pathogenic	0.804
SLC26A4	O43511-1.1	Q771R	Neutral	0.407
SLC26A4	O43511-1.1	Q771S	Pathogenic	0.558
SLC26A4	O43511-1.1	Q771T	Pathogenic	0.848
SLC26A4	O43511-1.1	Q771V	Pathogenic	0.93
SLC26A4	O43511-1.1	Q771W	Pathogenic	0.596
SLC26A4	O43511-1.1	Q771Y	Pathogenic	0.765
SLC26A4	O43511-1.1	D772A	Pathogenic	0.682
SLC26A4	O43511-1.1	D772C	Pathogenic	0.887
SLC26A4	O43511-1.1	D772E	Neutral	0.199
SLC26A4	O43511-1.1	D772F	Neutral	0.497
SLC26A4	O43511-1.1	D772G	Neutral	0.338
SLC26A4	O43511-1.1	D772H	Neutral	0.5
SLC26A4	O43511-1.1	D772I	Pathogenic	0.618
SLC26A4	O43511-1.1	D772K	Neutral	0.376
SLC26A4	O43511-1.1	D772L	Pathogenic	0.772
SLC26A4	O43511-1.1	D772M	Pathogenic	0.668
SLC26A4	O43511-1.1	D772N	Neutral	0.47
SLC26A4	O43511-1.1	D772P	Pathogenic	0.721
SLC26A4	O43511-1.1	D772Q	Neutral	0.406
SLC26A4	O43511-1.1	D772R	Neutral	0.401
SLC26A4	O43511-1.1	D772S	Neutral	0.444
SLC26A4	O43511-1.1	D772T	Pathogenic	0.747
SLC26A4	O43511-1.1	D772V	Pathogenic	0.827
SLC26A4	O43511-1.1	D772W	Neutral	0.32
SLC26A4	O43511-1.1	D772Y	Pathogenic	0.509
SLC26A4	O43511-1.1	E773A	Neutral	0.16
SLC26A4	O43511-1.1	E773C	Pathogenic	0.737
SLC26A4	O43511-1.1	E773D	Neutral	0.087
SLC26A4	O43511-1.1	E773F	Neutral	0.472
SLC26A4	O43511-1.1	E773G	Neutral	0.154
SLC26A4	O43511-1.1	E773H	Neutral	0.31
SLC26A4	O43511-1.1	E773I	Pathogenic	0.593
SLC26A4	O43511-1.1	E773K	Neutral	0.109
SLC26A4	O43511-1.1	E773L	Pathogenic	0.603
SLC26A4	O43511-1.1	E773M	Neutral	0.475
SLC26A4	O43511-1.1	E773N	Neutral	0.332
SLC26A4	O43511-1.1	E773P	Neutral	0.314
SLC26A4	O43511-1.1	E773Q	Neutral	0.132
SLC26A4	O43511-1.1	E773R	Neutral	0.119
SLC26A4	O43511-1.1	E773S	Neutral	0.124
SLC26A4	O43511-1.1	E773T	Neutral	0.385
SLC26A4	O43511-1.1	E773V	Pathogenic	0.599
SLC26A4	O43511-1.1	E773W	Neutral	0.174
SLC26A4	O43511-1.1	E773Y	Neutral	0.318
SLC26A4	O43511-1.1	A774C	Neutral	0.076
SLC26A4	O43511-1.1	A774D	Neutral	0.185
SLC26A4	O43511-1.1	A774E	Neutral	0.05
SLC26A4	O43511-1.1	A774F	Neutral	0.026
SLC26A4	O43511-1.1	A774G	Neutral	0.086
SLC26A4	O43511-1.1	A774H	Neutral	0.087
SLC26A4	O43511-1.1	A774I	Neutral	0.021
SLC26A4	O43511-1.1	A774K	Neutral	0.014
SLC26A4	O43511-1.1	A774L	Neutral	0.022
SLC26A4	O43511-1.1	A774M	Neutral	0.026
SLC26A4	O43511-1.1	A774N	Neutral	0.162
SLC26A4	O43511-1.1	A774P	Neutral	0.132
SLC26A4	O43511-1.1	A774Q	Neutral	0.047
SLC26A4	O43511-1.1	A774R	Neutral	0.008
SLC26A4	O43511-1.1	A774S	Neutral	0.077
SLC26A4	O43511-1.1	A774T	Neutral	0.071
SLC26A4	O43511-1.1	A774V	Neutral	0.031
SLC26A4	O43511-1.1	A774W	Neutral	0.012
SLC26A4	O43511-1.1	A774Y	Neutral	0.027
SLC26A4	O43511-1.1	M775A	Neutral	0.257
SLC26A4	O43511-1.1	M775C	Pathogenic	0.514
SLC26A4	O43511-1.1	M775D	Pathogenic	0.731
SLC26A4	O43511-1.1	M775E	Pathogenic	0.763
SLC26A4	O43511-1.1	M775F	Pathogenic	0.612
SLC26A4	O43511-1.1	M775G	Neutral	0.344
SLC26A4	O43511-1.1	M775H	Pathogenic	0.866
SLC26A4	O43511-1.1	M775I	Pathogenic	0.562
SLC26A4	O43511-1.1	M775K	Pathogenic	0.626
SLC26A4	O43511-1.1	M775L	Neutral	0.4
SLC26A4	O43511-1.1	M775N	Pathogenic	0.644
SLC26A4	O43511-1.1	M775P	Pathogenic	0.697
SLC26A4	O43511-1.1	M775Q	Pathogenic	0.539
SLC26A4	O43511-1.1	M775R	Neutral	0.48
SLC26A4	O43511-1.1	M775S	Neutral	0.284
SLC26A4	O43511-1.1	M775T	Pathogenic	0.523
SLC26A4	O43511-1.1	M775V	Neutral	0.403
SLC26A4	O43511-1.1	M775W	Neutral	0.429
SLC26A4	O43511-1.1	M775Y	Pathogenic	0.73
SLC26A4	O43511-1.1	R776A	Neutral	0.085
SLC26A4	O43511-1.1	R776C	Neutral	0.404
SLC26A4	O43511-1.1	R776D	Neutral	0.454
SLC26A4	O43511-1.1	R776E	Neutral	0.306
SLC26A4	O43511-1.1	R776F	Pathogenic	0.82
SLC26A4	O43511-1.1	R776G	Neutral	0.082
SLC26A4	O43511-1.1	R776H	Neutral	0.33
SLC26A4	O43511-1.1	R776I	Pathogenic	0.733
SLC26A4	O43511-1.1	R776K	Neutral	0.288
SLC26A4	O43511-1.1	R776L	Pathogenic	0.588
SLC26A4	O43511-1.1	R776M	Neutral	0.459
SLC26A4	O43511-1.1	R776N	Neutral	0.195
SLC26A4	O43511-1.1	R776P	Neutral	0.31
SLC26A4	O43511-1.1	R776Q	Neutral	0.19
SLC26A4	O43511-1.1	R776S	Neutral	0.122
SLC26A4	O43511-1.1	R776T	Neutral	0.234
SLC26A4	O43511-1.1	R776V	Pathogenic	0.594
SLC26A4	O43511-1.1	R776W	Pathogenic	0.777
SLC26A4	O43511-1.1	R776Y	Pathogenic	0.803
SLC26A4	O43511-1.1	T777A	Neutral	0.008
SLC26A4	O43511-1.1	T777C	Neutral	0.027
SLC26A4	O43511-1.1	T777D	Neutral	0.03
SLC26A4	O43511-1.1	T777E	Neutral	0.017
SLC26A4	O43511-1.1	T777F	Neutral	0.008
SLC26A4	O43511-1.1	T777G	Neutral	0.012
SLC26A4	O43511-1.1	T777H	Neutral	0.031
SLC26A4	O43511-1.1	T777I	Neutral	0.007
SLC26A4	O43511-1.1	T777K	Neutral	0.005
SLC26A4	O43511-1.1	T777L	Neutral	0.007
SLC26A4	O43511-1.1	T777M	Neutral	0.009
SLC26A4	O43511-1.1	T777N	Neutral	0.016
SLC26A4	O43511-1.1	T777P	Neutral	0.036
SLC26A4	O43511-1.1	T777Q	Neutral	0.016
SLC26A4	O43511-1.1	T777R	Neutral	0.003
SLC26A4	O43511-1.1	T777S	Neutral	0.005
SLC26A4	O43511-1.1	T777V	Neutral	0.01
SLC26A4	O43511-1.1	T777W	Neutral	0.002
SLC26A4	O43511-1.1	T777Y	Neutral	0.009
SLC26A4	O43511-1.1	L778A	Neutral	0.112
SLC26A4	O43511-1.1	L778C	Neutral	0.278
SLC26A4	O43511-1.1	L778D	Pathogenic	0.666
SLC26A4	O43511-1.1	L778E	Pathogenic	0.702
SLC26A4	O43511-1.1	L778F	Neutral	0.453
SLC26A4	O43511-1.1	L778G	Neutral	0.278
SLC26A4	O43511-1.1	L778H	Pathogenic	0.826
SLC26A4	O43511-1.1	L778I	Neutral	0.251
SLC26A4	O43511-1.1	L778K	Pathogenic	0.55
SLC26A4	O43511-1.1	L778M	Neutral	0.225
SLC26A4	O43511-1.1	L778N	Pathogenic	0.57
SLC26A4	O43511-1.1	L778P	Pathogenic	0.627
SLC26A4	O43511-1.1	L778Q	Pathogenic	0.633
SLC26A4	O43511-1.1	L778R	Neutral	0.404
SLC26A4	O43511-1.1	L778S	Neutral	0.225
SLC26A4	O43511-1.1	L778T	Neutral	0.285
SLC26A4	O43511-1.1	L778V	Neutral	0.198
SLC26A4	O43511-1.1	L778W	Neutral	0.441
SLC26A4	O43511-1.1	L778Y	Neutral	0.496
SLC26A4	O43511-1.1	A779C	Neutral	0.295
SLC26A4	O43511-1.1	A779D	Pathogenic	0.536
SLC26A4	O43511-1.1	A779E	Neutral	0.212
SLC26A4	O43511-1.1	A779F	Neutral	0.12
SLC26A4	O43511-1.1	A779G	Neutral	0.326
SLC26A4	O43511-1.1	A779H	Neutral	0.326
SLC26A4	O43511-1.1	A779I	Neutral	0.099
SLC26A4	O43511-1.1	A779K	Neutral	0.068
SLC26A4	O43511-1.1	A779L	Neutral	0.103
SLC26A4	O43511-1.1	A779M	Neutral	0.121
SLC26A4	O43511-1.1	A779N	Neutral	0.496
SLC26A4	O43511-1.1	A779P	Neutral	0.438
SLC26A4	O43511-1.1	A779Q	Neutral	0.201
SLC26A4	O43511-1.1	A779R	Neutral	0.039
SLC26A4	O43511-1.1	A779S	Neutral	0.299
SLC26A4	O43511-1.1	A779T	Neutral	0.28
SLC26A4	O43511-1.1	A779V	Neutral	0.14
SLC26A4	O43511-1.1	A779W	Neutral	0.061
SLC26A4	O43511-1.1	A779Y	Neutral	0.125
SLC26A4	O43511-1.1	S780A	Neutral	0.237
SLC26A4	O43511-1.1	S780C	Neutral	0.414
SLC26A4	O43511-1.1	S780D	Neutral	0.238
SLC26A4	O43511-1.1	S780E	Neutral	0.127
SLC26A4	O43511-1.1	S780F	Neutral	0.102
SLC26A4	O43511-1.1	S780G	Neutral	0.23
SLC26A4	O43511-1.1	S780H	Neutral	0.188
SLC26A4	O43511-1.1	S780I	Neutral	0.157
SLC26A4	O43511-1.1	S780K	Neutral	0.038
SLC26A4	O43511-1.1	S780L	Neutral	0.162
SLC26A4	O43511-1.1	S780M	Neutral	0.103
SLC26A4	O43511-1.1	S780N	Neutral	0.117
SLC26A4	O43511-1.1	S780P	Neutral	0.395
SLC26A4	O43511-1.1	S780Q	Neutral	0.12
SLC26A4	O43511-1.1	S780R	Neutral	0.042
SLC26A4	O43511-1.1	S780T	Neutral	0.144
SLC26A4	O43511-1.1	S780V	Neutral	0.354
SLC26A4	O43511-1.1	S780W	Neutral	0.051
SLC26A4	O43511-1.1	S780Y	Neutral	0.107
OPA1	O60313-1.3	M1A	Neutral	0.126
OPA1	O60313-1.3	M1C	Neutral	0.223
OPA1	O60313-1.3	M1D	Neutral	0.331
OPA1	O60313-1.3	M1E	Neutral	0.171
OPA1	O60313-1.3	M1F	Neutral	0.076
OPA1	O60313-1.3	M1G	Neutral	0.46
OPA1	O60313-1.3	M1H	Neutral	0.301
OPA1	O60313-1.3	M1I	Neutral	0.028
OPA1	O60313-1.3	M1K	Neutral	0.05
OPA1	O60313-1.3	M1L	Neutral	0.011
OPA1	O60313-1.3	M1N	Neutral	0.169
OPA1	O60313-1.3	M1P	Neutral	0.399
OPA1	O60313-1.3	M1Q	Neutral	0.035
OPA1	O60313-1.3	M1R	Neutral	0.047
OPA1	O60313-1.3	M1S	Neutral	0.097
OPA1	O60313-1.3	M1T	Neutral	0.132
OPA1	O60313-1.3	M1V	Neutral	0.043
OPA1	O60313-1.3	M1W	Neutral	0.124
OPA1	O60313-1.3	M1Y	Neutral	0.233
OPA1	O60313-1.3	W2A	Pathogenic	0.634
OPA1	O60313-1.3	W2C	Pathogenic	0.543
OPA1	O60313-1.3	W2D	Pathogenic	0.672
OPA1	O60313-1.3	W2E	Neutral	0.46
OPA1	O60313-1.3	W2F	Neutral	0.109
OPA1	O60313-1.3	W2G	Neutral	0.296
OPA1	O60313-1.3	W2H	Neutral	0.381
OPA1	O60313-1.3	W2I	Pathogenic	0.894
OPA1	O60313-1.3	W2K	Neutral	0.405
OPA1	O60313-1.3	W2L	Pathogenic	0.726
OPA1	O60313-1.3	W2M	Neutral	0.373
OPA1	O60313-1.3	W2N	Pathogenic	0.709
OPA1	O60313-1.3	W2P	Pathogenic	0.889
OPA1	O60313-1.3	W2Q	Neutral	0.305
OPA1	O60313-1.3	W2R	Neutral	0.414
OPA1	O60313-1.3	W2S	Pathogenic	0.564
OPA1	O60313-1.3	W2T	Neutral	0.386
OPA1	O60313-1.3	W2V	Pathogenic	0.821
OPA1	O60313-1.3	W2Y	Neutral	0.02
OPA1	O60313-1.3	R3A	Neutral	0.077
OPA1	O60313-1.3	R3C	Neutral	0.29
OPA1	O60313-1.3	R3D	Neutral	0.416
OPA1	O60313-1.3	R3E	Neutral	0.074
OPA1	O60313-1.3	R3F	Neutral	0.19
OPA1	O60313-1.3	R3G	Neutral	0.231
OPA1	O60313-1.3	R3H	Neutral	0.04
OPA1	O60313-1.3	R3I	Neutral	0.182
OPA1	O60313-1.3	R3K	Neutral	0.014
OPA1	O60313-1.3	R3L	Neutral	0.078
OPA1	O60313-1.3	R3M	Neutral	0.043
OPA1	O60313-1.3	R3N	Neutral	0.069
OPA1	O60313-1.3	R3P	Neutral	0.154
OPA1	O60313-1.3	R3Q	Neutral	0.019
OPA1	O60313-1.3	R3S	Neutral	0.105
OPA1	O60313-1.3	R3T	Neutral	0.088
OPA1	O60313-1.3	R3V	Neutral	0.261
OPA1	O60313-1.3	R3W	Neutral	0.132
OPA1	O60313-1.3	R3Y	Neutral	0.15
OPA1	O60313-1.3	L4A	Neutral	0.008
OPA1	O60313-1.3	L4C	Neutral	0.016
OPA1	O60313-1.3	L4D	Neutral	0.073
OPA1	O60313-1.3	L4E	Neutral	0.032
OPA1	O60313-1.3	L4F	Neutral	0.011
OPA1	O60313-1.3	L4G	Neutral	0.12
OPA1	O60313-1.3	L4H	Neutral	0.064
OPA1	O60313-1.3	L4I	Neutral	0.001
OPA1	O60313-1.3	L4K	Neutral	0.008
OPA1	O60313-1.3	L4M	Neutral	0.001
OPA1	O60313-1.3	L4N	Neutral	0.031
OPA1	O60313-1.3	L4P	Neutral	0.096
OPA1	O60313-1.3	L4Q	Neutral	0.017
OPA1	O60313-1.3	L4R	Neutral	0.008
OPA1	O60313-1.3	L4S	Neutral	0.017
OPA1	O60313-1.3	L4T	Neutral	0.008
OPA1	O60313-1.3	L4V	Neutral	0.003
OPA1	O60313-1.3	L4W	Neutral	0.051
OPA1	O60313-1.3	L4Y	Neutral	0.017
OPA1	O60313-1.3	R5A	Neutral	0.033
OPA1	O60313-1.3	R5C	Neutral	0.143
OPA1	O60313-1.3	R5D	Neutral	0.226
OPA1	O60313-1.3	R5E	Neutral	0.032
OPA1	O60313-1.3	R5F	Neutral	0.087
OPA1	O60313-1.3	R5G	Neutral	0.109
OPA1	O60313-1.3	R5H	Neutral	0.017
OPA1	O60313-1.3	R5I	Neutral	0.083
OPA1	O60313-1.3	R5K	Neutral	0.006
OPA1	O60313-1.3	R5L	Neutral	0.033
OPA1	O60313-1.3	R5M	Neutral	0.018
OPA1	O60313-1.3	R5N	Neutral	0.029
OPA1	O60313-1.3	R5P	Neutral	0.069
OPA1	O60313-1.3	R5Q	Neutral	0.008
OPA1	O60313-1.3	R5S	Neutral	0.046
OPA1	O60313-1.3	R5T	Neutral	0.038
OPA1	O60313-1.3	R5V	Neutral	0.126
OPA1	O60313-1.3	R5W	Neutral	0.059
OPA1	O60313-1.3	R5Y	Neutral	0.067
OPA1	O60313-1.3	R6A	Neutral	0.008
OPA1	O60313-1.3	R6C	Neutral	0.036
OPA1	O60313-1.3	R6D	Neutral	0.06
OPA1	O60313-1.3	R6E	Neutral	0.007
OPA1	O60313-1.3	R6F	Neutral	0.021
OPA1	O60313-1.3	R6G	Neutral	0.026
OPA1	O60313-1.3	R6H	Neutral	0.004
OPA1	O60313-1.3	R6I	Neutral	0.02
OPA1	O60313-1.3	R6K	Neutral	0.001
OPA1	O60313-1.3	R6L	Neutral	0.008
OPA1	O60313-1.3	R6M	Neutral	0.004
OPA1	O60313-1.3	R6N	Neutral	0.007
OPA1	O60313-1.3	R6P	Neutral	0.016
OPA1	O60313-1.3	R6Q	Neutral	0.002
OPA1	O60313-1.3	R6S	Neutral	0.011
OPA1	O60313-1.3	R6T	Neutral	0.009
OPA1	O60313-1.3	R6V	Neutral	0.031
OPA1	O60313-1.3	R6W	Neutral	0.014
OPA1	O60313-1.3	R6Y	Neutral	0.016
OPA1	O60313-1.3	A7C	Neutral	0.01
OPA1	O60313-1.3	A7D	Neutral	0.052
OPA1	O60313-1.3	A7E	Neutral	0.02
OPA1	O60313-1.3	A7F	Neutral	0.031
OPA1	O60313-1.3	A7G	Neutral	0.013
OPA1	O60313-1.3	A7H	Neutral	0.102
OPA1	O60313-1.3	A7I	Neutral	0.011
OPA1	O60313-1.3	A7K	Neutral	0.013
OPA1	O60313-1.3	A7L	Neutral	0.012
OPA1	O60313-1.3	A7M	Neutral	0.019
OPA1	O60313-1.3	A7N	Neutral	0.06
OPA1	O60313-1.3	A7P	Neutral	0.034
OPA1	O60313-1.3	A7Q	Neutral	0.028
OPA1	O60313-1.3	A7R	Neutral	0.012
OPA1	O60313-1.3	A7S	Neutral	0.005
OPA1	O60313-1.3	A7T	Neutral	0.016
OPA1	O60313-1.3	A7V	Neutral	0.007
OPA1	O60313-1.3	A7W	Neutral	0.053
OPA1	O60313-1.3	A7Y	Neutral	0.063
OPA1	O60313-1.3	A8C	Neutral	0.003
OPA1	O60313-1.3	A8D	Neutral	0.019
OPA1	O60313-1.3	A8E	Neutral	0.007
OPA1	O60313-1.3	A8F	Neutral	0.011
OPA1	O60313-1.3	A8G	Neutral	0.005
OPA1	O60313-1.3	A8H	Neutral	0.039
OPA1	O60313-1.3	A8I	Neutral	0.004
OPA1	O60313-1.3	A8K	Neutral	0.005
OPA1	O60313-1.3	A8L	Neutral	0.004
OPA1	O60313-1.3	A8M	Neutral	0.007
OPA1	O60313-1.3	A8N	Neutral	0.022
OPA1	O60313-1.3	A8P	Neutral	0.012
OPA1	O60313-1.3	A8Q	Neutral	0.01
OPA1	O60313-1.3	A8R	Neutral	0.004
OPA1	O60313-1.3	A8S	Neutral	0.002
OPA1	O60313-1.3	A8T	Neutral	0.006
OPA1	O60313-1.3	A8V	Neutral	0.003
OPA1	O60313-1.3	A8W	Neutral	0.019
OPA1	O60313-1.3	A8Y	Neutral	0.023
OPA1	O60313-1.3	V9A	Neutral	0.004
OPA1	O60313-1.3	V9C	Neutral	0.024
OPA1	O60313-1.3	V9D	Neutral	0.041
OPA1	O60313-1.3	V9E	Neutral	0.017
OPA1	O60313-1.3	V9F	Neutral	0.017
OPA1	O60313-1.3	V9G	Neutral	0.068
OPA1	O60313-1.3	V9H	Neutral	0.088
OPA1	O60313-1.3	V9I	Neutral	0.0
OPA1	O60313-1.3	V9K	Neutral	0.011
OPA1	O60313-1.3	V9L	Neutral	0.002
OPA1	O60313-1.3	V9M	Neutral	0.004
OPA1	O60313-1.3	V9N	Neutral	0.048
OPA1	O60313-1.3	V9P	Neutral	0.054
OPA1	O60313-1.3	V9Q	Neutral	0.024
OPA1	O60313-1.3	V9R	Neutral	0.03
OPA1	O60313-1.3	V9S	Neutral	0.026
OPA1	O60313-1.3	V9T	Neutral	0.004
OPA1	O60313-1.3	V9W	Neutral	0.079
OPA1	O60313-1.3	V9Y	Neutral	0.022
OPA1	O60313-1.3	A10C	Neutral	0.008
OPA1	O60313-1.3	A10D	Neutral	0.046
OPA1	O60313-1.3	A10E	Neutral	0.017
OPA1	O60313-1.3	A10F	Neutral	0.027
OPA1	O60313-1.3	A10G	Neutral	0.012
OPA1	O60313-1.3	A10H	Neutral	0.09
OPA1	O60313-1.3	A10I	Neutral	0.01
OPA1	O60313-1.3	A10K	Neutral	0.011
OPA1	O60313-1.3	A10L	Neutral	0.011
OPA1	O60313-1.3	A10M	Neutral	0.017
OPA1	O60313-1.3	A10N	Neutral	0.052
OPA1	O60313-1.3	A10P	Neutral	0.03
OPA1	O60313-1.3	A10Q	Neutral	0.025
OPA1	O60313-1.3	A10R	Neutral	0.011
OPA1	O60313-1.3	A10S	Neutral	0.004
OPA1	O60313-1.3	A10T	Neutral	0.014
OPA1	O60313-1.3	A10V	Neutral	0.006
OPA1	O60313-1.3	A10W	Neutral	0.046
OPA1	O60313-1.3	A10Y	Neutral	0.056
OPA1	O60313-1.3	C11A	Neutral	0.061
OPA1	O60313-1.3	C11D	Neutral	0.384
OPA1	O60313-1.3	C11E	Pathogenic	0.656
OPA1	O60313-1.3	C11F	Neutral	0.303
OPA1	O60313-1.3	C11G	Pathogenic	0.527
OPA1	O60313-1.3	C11H	Pathogenic	0.563
OPA1	O60313-1.3	C11I	Neutral	0.133
OPA1	O60313-1.3	C11K	Neutral	0.302
OPA1	O60313-1.3	C11L	Neutral	0.145
OPA1	O60313-1.3	C11M	Neutral	0.206
OPA1	O60313-1.3	C11N	Neutral	0.417
OPA1	O60313-1.3	C11P	Pathogenic	0.71
OPA1	O60313-1.3	C11Q	Neutral	0.486
OPA1	O60313-1.3	C11R	Neutral	0.289
OPA1	O60313-1.3	C11S	Neutral	0.124
OPA1	O60313-1.3	C11T	Neutral	0.159
OPA1	O60313-1.3	C11V	Neutral	0.22
OPA1	O60313-1.3	C11W	Neutral	0.204
OPA1	O60313-1.3	C11Y	Neutral	0.465
OPA1	O60313-1.3	E12A	Neutral	0.015
OPA1	O60313-1.3	E12C	Neutral	0.173
OPA1	O60313-1.3	E12D	Neutral	0.001
OPA1	O60313-1.3	E12F	Neutral	0.033
OPA1	O60313-1.3	E12G	Neutral	0.051
OPA1	O60313-1.3	E12H	Neutral	0.007
OPA1	O60313-1.3	E12I	Neutral	0.034
OPA1	O60313-1.3	E12K	Neutral	0.003
OPA1	O60313-1.3	E12L	Neutral	0.037
OPA1	O60313-1.3	E12M	Neutral	0.02
OPA1	O60313-1.3	E12N	Neutral	0.013
OPA1	O60313-1.3	E12P	Neutral	0.011
OPA1	O60313-1.3	E12Q	Neutral	0.001
OPA1	O60313-1.3	E12R	Neutral	0.009
OPA1	O60313-1.3	E12S	Neutral	0.007
OPA1	O60313-1.3	E12T	Neutral	0.017
OPA1	O60313-1.3	E12V	Neutral	0.021
OPA1	O60313-1.3	E12W	Neutral	0.02
OPA1	O60313-1.3	E12Y	Neutral	0.024
OPA1	O60313-1.3	V13A	Neutral	0.011
OPA1	O60313-1.3	V13C	Neutral	0.059
OPA1	O60313-1.3	V13D	Neutral	0.098
OPA1	O60313-1.3	V13E	Neutral	0.042
OPA1	O60313-1.3	V13F	Neutral	0.042
OPA1	O60313-1.3	V13G	Neutral	0.157
OPA1	O60313-1.3	V13H	Neutral	0.199
OPA1	O60313-1.3	V13I	Neutral	0.001
OPA1	O60313-1.3	V13K	Neutral	0.028
OPA1	O60313-1.3	V13L	Neutral	0.006
OPA1	O60313-1.3	V13M	Neutral	0.009
OPA1	O60313-1.3	V13N	Neutral	0.114
OPA1	O60313-1.3	V13P	Neutral	0.127
OPA1	O60313-1.3	V13Q	Neutral	0.059
OPA1	O60313-1.3	V13R	Neutral	0.073
OPA1	O60313-1.3	V13S	Neutral	0.064
OPA1	O60313-1.3	V13T	Neutral	0.011
OPA1	O60313-1.3	V13W	Neutral	0.18
OPA1	O60313-1.3	V13Y	Neutral	0.055
OPA1	O60313-1.3	C14A	Neutral	0.451
OPA1	O60313-1.3	C14D	Pathogenic	0.887
OPA1	O60313-1.3	C14E	Pathogenic	0.96
OPA1	O60313-1.3	C14F	Pathogenic	0.845
OPA1	O60313-1.3	C14G	Pathogenic	0.934
OPA1	O60313-1.3	C14H	Pathogenic	0.942
OPA1	O60313-1.3	C14I	Pathogenic	0.66
OPA1	O60313-1.3	C14K	Pathogenic	0.845
OPA1	O60313-1.3	C14L	Pathogenic	0.681
OPA1	O60313-1.3	C14M	Pathogenic	0.766
OPA1	O60313-1.3	C14N	Pathogenic	0.9
OPA1	O60313-1.3	C14P	Pathogenic	0.969
OPA1	O60313-1.3	C14Q	Pathogenic	0.923
OPA1	O60313-1.3	C14R	Pathogenic	0.837
OPA1	O60313-1.3	C14S	Pathogenic	0.64
OPA1	O60313-1.3	C14T	Pathogenic	0.704
OPA1	O60313-1.3	C14V	Pathogenic	0.781
OPA1	O60313-1.3	C14W	Pathogenic	0.764
OPA1	O60313-1.3	C14Y	Pathogenic	0.916
OPA1	O60313-1.3	Q15A	Neutral	0.013
OPA1	O60313-1.3	Q15C	Neutral	0.062
OPA1	O60313-1.3	Q15D	Neutral	0.005
OPA1	O60313-1.3	Q15E	Neutral	0.001
OPA1	O60313-1.3	Q15F	Neutral	0.031
OPA1	O60313-1.3	Q15G	Neutral	0.046
OPA1	O60313-1.3	Q15H	Neutral	0.006
OPA1	O60313-1.3	Q15I	Neutral	0.032
OPA1	O60313-1.3	Q15K	Neutral	0.001
OPA1	O60313-1.3	Q15L	Neutral	0.012
OPA1	O60313-1.3	Q15M	Neutral	0.002
OPA1	O60313-1.3	Q15N	Neutral	0.006
OPA1	O60313-1.3	Q15P	Neutral	0.01
OPA1	O60313-1.3	Q15R	Neutral	0.001
OPA1	O60313-1.3	Q15S	Neutral	0.006
OPA1	O60313-1.3	Q15T	Neutral	0.015
OPA1	O60313-1.3	Q15V	Neutral	0.019
OPA1	O60313-1.3	Q15W	Neutral	0.007
OPA1	O60313-1.3	Q15Y	Neutral	0.008
OPA1	O60313-1.3	S16A	Neutral	0.004
OPA1	O60313-1.3	S16C	Neutral	0.017
OPA1	O60313-1.3	S16D	Neutral	0.008
OPA1	O60313-1.3	S16E	Neutral	0.008
OPA1	O60313-1.3	S16F	Neutral	0.02
OPA1	O60313-1.3	S16G	Neutral	0.014
OPA1	O60313-1.3	S16H	Neutral	0.032
OPA1	O60313-1.3	S16I	Neutral	0.02
OPA1	O60313-1.3	S16K	Neutral	0.005
OPA1	O60313-1.3	S16L	Neutral	0.022
OPA1	O60313-1.3	S16M	Neutral	0.012
OPA1	O60313-1.3	S16N	Neutral	0.003
OPA1	O60313-1.3	S16P	Neutral	0.021
OPA1	O60313-1.3	S16Q	Neutral	0.011
OPA1	O60313-1.3	S16R	Neutral	0.014
OPA1	O60313-1.3	S16T	Neutral	0.004
OPA1	O60313-1.3	S16V	Neutral	0.036
OPA1	O60313-1.3	S16W	Neutral	0.033
OPA1	O60313-1.3	S16Y	Neutral	0.04
OPA1	O60313-1.3	L17A	Neutral	0.133
OPA1	O60313-1.3	L17C	Neutral	0.235
OPA1	O60313-1.3	L17D	Pathogenic	0.605
OPA1	O60313-1.3	L17E	Neutral	0.389
OPA1	O60313-1.3	L17F	Neutral	0.172
OPA1	O60313-1.3	L17G	Pathogenic	0.725
OPA1	O60313-1.3	L17H	Pathogenic	0.571
OPA1	O60313-1.3	L17I	Neutral	0.025
OPA1	O60313-1.3	L17K	Neutral	0.139
OPA1	O60313-1.3	L17M	Neutral	0.018
OPA1	O60313-1.3	L17N	Neutral	0.386
OPA1	O60313-1.3	L17P	Pathogenic	0.672
OPA1	O60313-1.3	L17Q	Neutral	0.247
OPA1	O60313-1.3	L17R	Neutral	0.132
OPA1	O60313-1.3	L17S	Neutral	0.25
OPA1	O60313-1.3	L17T	Neutral	0.139
OPA1	O60313-1.3	L17V	Neutral	0.046
OPA1	O60313-1.3	L17W	Pathogenic	0.508
OPA1	O60313-1.3	L17Y	Neutral	0.245
OPA1	O60313-1.3	V18A	Neutral	0.009
OPA1	O60313-1.3	V18C	Neutral	0.052
OPA1	O60313-1.3	V18D	Neutral	0.086
OPA1	O60313-1.3	V18E	Neutral	0.037
OPA1	O60313-1.3	V18F	Neutral	0.037
OPA1	O60313-1.3	V18G	Neutral	0.14
OPA1	O60313-1.3	V18H	Neutral	0.178
OPA1	O60313-1.3	V18I	Neutral	0.001
OPA1	O60313-1.3	V18K	Neutral	0.024
OPA1	O60313-1.3	V18L	Neutral	0.005
OPA1	O60313-1.3	V18M	Neutral	0.008
OPA1	O60313-1.3	V18N	Neutral	0.101
OPA1	O60313-1.3	V18P	Neutral	0.112
OPA1	O60313-1.3	V18Q	Neutral	0.052
OPA1	O60313-1.3	V18R	Neutral	0.064
OPA1	O60313-1.3	V18S	Neutral	0.056
OPA1	O60313-1.3	V18T	Neutral	0.01
OPA1	O60313-1.3	V18W	Neutral	0.161
OPA1	O60313-1.3	V18Y	Neutral	0.048
OPA1	O60313-1.3	K19A	Neutral	0.001
OPA1	O60313-1.3	K19C	Neutral	0.005
OPA1	O60313-1.3	K19D	Neutral	0.003
OPA1	O60313-1.3	K19E	Neutral	0.0
OPA1	O60313-1.3	K19F	Neutral	0.003
OPA1	O60313-1.3	K19G	Neutral	0.004
OPA1	O60313-1.3	K19H	Neutral	0.001
OPA1	O60313-1.3	K19I	Neutral	0.003
OPA1	O60313-1.3	K19L	Neutral	0.001
OPA1	O60313-1.3	K19M	Neutral	0.001
OPA1	O60313-1.3	K19N	Neutral	0.001
OPA1	O60313-1.3	K19P	Neutral	0.001
OPA1	O60313-1.3	K19Q	Neutral	0.0
OPA1	O60313-1.3	K19R	Neutral	0.0
OPA1	O60313-1.3	K19S	Neutral	0.0
OPA1	O60313-1.3	K19T	Neutral	0.001
OPA1	O60313-1.3	K19V	Neutral	0.001
OPA1	O60313-1.3	K19W	Neutral	0.002
OPA1	O60313-1.3	K19Y	Neutral	0.002
OPA1	O60313-1.3	H20A	Neutral	0.016
OPA1	O60313-1.3	H20C	Neutral	0.027
OPA1	O60313-1.3	H20D	Neutral	0.003
OPA1	O60313-1.3	H20E	Neutral	0.001
OPA1	O60313-1.3	H20F	Neutral	0.002
OPA1	O60313-1.3	H20G	Neutral	0.016
OPA1	O60313-1.3	H20I	Neutral	0.014
OPA1	O60313-1.3	H20K	Neutral	0.003
OPA1	O60313-1.3	H20L	Neutral	0.016
OPA1	O60313-1.3	H20M	Neutral	0.008
OPA1	O60313-1.3	H20N	Neutral	0.0
OPA1	O60313-1.3	H20P	Neutral	0.012
OPA1	O60313-1.3	H20Q	Neutral	0.002
OPA1	O60313-1.3	H20R	Neutral	0.001
OPA1	O60313-1.3	H20S	Neutral	0.006
OPA1	O60313-1.3	H20T	Neutral	0.019
OPA1	O60313-1.3	H20V	Neutral	0.024
OPA1	O60313-1.3	H20W	Neutral	0.003
OPA1	O60313-1.3	H20Y	Neutral	0.0
OPA1	O60313-1.3	S21A	Neutral	0.006
OPA1	O60313-1.3	S21C	Neutral	0.027
OPA1	O60313-1.3	S21D	Neutral	0.012
OPA1	O60313-1.3	S21E	Neutral	0.013
OPA1	O60313-1.3	S21F	Neutral	0.031
OPA1	O60313-1.3	S21G	Neutral	0.022
OPA1	O60313-1.3	S21H	Neutral	0.051
OPA1	O60313-1.3	S21I	Neutral	0.032
OPA1	O60313-1.3	S21K	Neutral	0.008
OPA1	O60313-1.3	S21L	Neutral	0.035
OPA1	O60313-1.3	S21M	Neutral	0.019
OPA1	O60313-1.3	S21N	Neutral	0.005
OPA1	O60313-1.3	S21P	Neutral	0.034
OPA1	O60313-1.3	S21Q	Neutral	0.018
OPA1	O60313-1.3	S21R	Neutral	0.023
OPA1	O60313-1.3	S21T	Neutral	0.006
OPA1	O60313-1.3	S21V	Neutral	0.057
OPA1	O60313-1.3	S21W	Neutral	0.052
OPA1	O60313-1.3	S21Y	Neutral	0.063
OPA1	O60313-1.3	S22A	Neutral	0.001
OPA1	O60313-1.3	S22C	Neutral	0.002
OPA1	O60313-1.3	S22D	Neutral	0.001
OPA1	O60313-1.3	S22E	Neutral	0.001
OPA1	O60313-1.3	S22F	Neutral	0.003
OPA1	O60313-1.3	S22G	Neutral	0.002
OPA1	O60313-1.3	S22H	Neutral	0.005
OPA1	O60313-1.3	S22I	Neutral	0.003
OPA1	O60313-1.3	S22K	Neutral	0.001
OPA1	O60313-1.3	S22L	Neutral	0.003
OPA1	O60313-1.3	S22M	Neutral	0.002
OPA1	O60313-1.3	S22N	Neutral	0.0
OPA1	O60313-1.3	S22P	Neutral	0.003
OPA1	O60313-1.3	S22Q	Neutral	0.002
OPA1	O60313-1.3	S22R	Neutral	0.002
OPA1	O60313-1.3	S22T	Neutral	0.001
OPA1	O60313-1.3	S22V	Neutral	0.005
OPA1	O60313-1.3	S22W	Neutral	0.005
OPA1	O60313-1.3	S22Y	Neutral	0.006
OPA1	O60313-1.3	G23A	Pathogenic	0.626
OPA1	O60313-1.3	G23C	Pathogenic	0.954
OPA1	O60313-1.3	G23D	Pathogenic	0.744
OPA1	O60313-1.3	G23E	Pathogenic	0.899
OPA1	O60313-1.3	G23F	Pathogenic	0.891
OPA1	O60313-1.3	G23H	Pathogenic	0.932
OPA1	O60313-1.3	G23I	Pathogenic	0.961
OPA1	O60313-1.3	G23K	Pathogenic	0.854
OPA1	O60313-1.3	G23L	Pathogenic	0.964
OPA1	O60313-1.3	G23M	Pathogenic	0.934
OPA1	O60313-1.3	G23N	Pathogenic	0.535
OPA1	O60313-1.3	G23P	Pathogenic	0.899
OPA1	O60313-1.3	G23Q	Pathogenic	0.928
OPA1	O60313-1.3	G23R	Pathogenic	0.846
OPA1	O60313-1.3	G23S	Pathogenic	0.677
OPA1	O60313-1.3	G23T	Pathogenic	0.931
OPA1	O60313-1.3	G23V	Pathogenic	0.939
OPA1	O60313-1.3	G23W	Pathogenic	0.624
OPA1	O60313-1.3	G23Y	Pathogenic	0.945
OPA1	O60313-1.3	I24A	Neutral	0.006
OPA1	O60313-1.3	I24C	Neutral	0.012
OPA1	O60313-1.3	I24D	Neutral	0.021
OPA1	O60313-1.3	I24E	Neutral	0.025
OPA1	O60313-1.3	I24F	Neutral	0.01
OPA1	O60313-1.3	I24G	Neutral	0.098
OPA1	O60313-1.3	I24H	Neutral	0.052
OPA1	O60313-1.3	I24K	Neutral	0.019
OPA1	O60313-1.3	I24L	Neutral	0.001
OPA1	O60313-1.3	I24M	Neutral	0.002
OPA1	O60313-1.3	I24N	Neutral	0.025
OPA1	O60313-1.3	I24P	Neutral	0.078
OPA1	O60313-1.3	I24Q	Neutral	0.038
OPA1	O60313-1.3	I24R	Neutral	0.018
OPA1	O60313-1.3	I24S	Neutral	0.013
OPA1	O60313-1.3	I24T	Neutral	0.007
OPA1	O60313-1.3	I24V	Neutral	0.0
OPA1	O60313-1.3	I24W	Neutral	0.129
OPA1	O60313-1.3	I24Y	Neutral	0.013
OPA1	O60313-1.3	K25A	Neutral	0.041
OPA1	O60313-1.3	K25C	Neutral	0.173
OPA1	O60313-1.3	K25D	Neutral	0.112
OPA1	O60313-1.3	K25E	Neutral	0.014
OPA1	O60313-1.3	K25F	Neutral	0.107
OPA1	O60313-1.3	K25G	Neutral	0.133
OPA1	O60313-1.3	K25H	Neutral	0.058
OPA1	O60313-1.3	K25I	Neutral	0.102
OPA1	O60313-1.3	K25L	Neutral	0.041
OPA1	O60313-1.3	K25M	Neutral	0.022
OPA1	O60313-1.3	K25N	Neutral	0.037
OPA1	O60313-1.3	K25P	Neutral	0.031
OPA1	O60313-1.3	K25Q	Neutral	0.01
OPA1	O60313-1.3	K25R	Neutral	0.007
OPA1	O60313-1.3	K25S	Neutral	0.02
OPA1	O60313-1.3	K25T	Neutral	0.047
OPA1	O60313-1.3	K25V	Neutral	0.059
OPA1	O60313-1.3	K25W	Neutral	0.066
OPA1	O60313-1.3	K25Y	Neutral	0.079
OPA1	O60313-1.3	G26A	Neutral	0.006
OPA1	O60313-1.3	G26C	Neutral	0.065
OPA1	O60313-1.3	G26D	Neutral	0.01
OPA1	O60313-1.3	G26E	Neutral	0.029
OPA1	O60313-1.3	G26F	Neutral	0.027
OPA1	O60313-1.3	G26H	Neutral	0.044
OPA1	O60313-1.3	G26I	Neutral	0.076
OPA1	O60313-1.3	G26K	Neutral	0.019
OPA1	O60313-1.3	G26L	Neutral	0.083
OPA1	O60313-1.3	G26M	Neutral	0.046
OPA1	O60313-1.3	G26N	Neutral	0.004
OPA1	O60313-1.3	G26P	Neutral	0.029
OPA1	O60313-1.3	G26Q	Neutral	0.042
OPA1	O60313-1.3	G26R	Neutral	0.018
OPA1	O60313-1.3	G26S	Neutral	0.007
OPA1	O60313-1.3	G26T	Neutral	0.043
OPA1	O60313-1.3	G26V	Neutral	0.05
OPA1	O60313-1.3	G26W	Neutral	0.006
OPA1	O60313-1.3	G26Y	Neutral	0.055
OPA1	O60313-1.3	S27A	Neutral	0.0
OPA1	O60313-1.3	S27C	Neutral	0.002
OPA1	O60313-1.3	S27D	Neutral	0.001
OPA1	O60313-1.3	S27E	Neutral	0.001
OPA1	O60313-1.3	S27F	Neutral	0.002
OPA1	O60313-1.3	S27G	Neutral	0.001
OPA1	O60313-1.3	S27H	Neutral	0.003
OPA1	O60313-1.3	S27I	Neutral	0.002
OPA1	O60313-1.3	S27K	Neutral	0.001
OPA1	O60313-1.3	S27L	Neutral	0.002
OPA1	O60313-1.3	S27M	Neutral	0.001
OPA1	O60313-1.3	S27N	Neutral	0.0
OPA1	O60313-1.3	S27P	Neutral	0.002
OPA1	O60313-1.3	S27Q	Neutral	0.001
OPA1	O60313-1.3	S27R	Neutral	0.001
OPA1	O60313-1.3	S27T	Neutral	0.0
OPA1	O60313-1.3	S27V	Neutral	0.004
OPA1	O60313-1.3	S27W	Neutral	0.003
OPA1	O60313-1.3	S27Y	Neutral	0.004
OPA1	O60313-1.3	L28A	Neutral	0.002
OPA1	O60313-1.3	L28C	Neutral	0.003
OPA1	O60313-1.3	L28D	Neutral	0.015
OPA1	O60313-1.3	L28E	Neutral	0.006
OPA1	O60313-1.3	L28F	Neutral	0.002
OPA1	O60313-1.3	L28G	Neutral	0.026
OPA1	O60313-1.3	L28H	Neutral	0.013
OPA1	O60313-1.3	L28I	Neutral	0.0
OPA1	O60313-1.3	L28K	Neutral	0.002
OPA1	O60313-1.3	L28M	Neutral	0.0
OPA1	O60313-1.3	L28N	Neutral	0.006
OPA1	O60313-1.3	L28P	Neutral	0.02
OPA1	O60313-1.3	L28Q	Neutral	0.003
OPA1	O60313-1.3	L28R	Neutral	0.002
OPA1	O60313-1.3	L28S	Neutral	0.003
OPA1	O60313-1.3	L28T	Neutral	0.002
OPA1	O60313-1.3	L28V	Neutral	0.0
OPA1	O60313-1.3	L28W	Neutral	0.01
OPA1	O60313-1.3	L28Y	Neutral	0.003
OPA1	O60313-1.3	P29A	Pathogenic	0.576
OPA1	O60313-1.3	P29C	Pathogenic	0.933
OPA1	O60313-1.3	P29D	Neutral	0.355
OPA1	O60313-1.3	P29E	Neutral	0.367
OPA1	O60313-1.3	P29F	Pathogenic	0.943
OPA1	O60313-1.3	P29G	Pathogenic	0.735
OPA1	O60313-1.3	P29H	Pathogenic	0.767
OPA1	O60313-1.3	P29I	Pathogenic	0.855
OPA1	O60313-1.3	P29K	Neutral	0.276
OPA1	O60313-1.3	P29L	Pathogenic	0.867
OPA1	O60313-1.3	P29M	Pathogenic	0.775
OPA1	O60313-1.3	P29N	Pathogenic	0.646
OPA1	O60313-1.3	P29Q	Neutral	0.455
OPA1	O60313-1.3	P29R	Pathogenic	0.51
OPA1	O60313-1.3	P29S	Pathogenic	0.504
OPA1	O60313-1.3	P29T	Pathogenic	0.583
OPA1	O60313-1.3	P29V	Pathogenic	0.789
OPA1	O60313-1.3	P29W	Pathogenic	0.908
OPA1	O60313-1.3	P29Y	Pathogenic	0.923
OPA1	O60313-1.3	L30A	Neutral	0.23
OPA1	O60313-1.3	L30C	Neutral	0.373
OPA1	O60313-1.3	L30D	Pathogenic	0.748
OPA1	O60313-1.3	L30E	Pathogenic	0.552
OPA1	O60313-1.3	L30F	Neutral	0.287
OPA1	O60313-1.3	L30G	Pathogenic	0.836
OPA1	O60313-1.3	L30H	Pathogenic	0.721
OPA1	O60313-1.3	L30I	Neutral	0.047
OPA1	O60313-1.3	L30K	Neutral	0.238
OPA1	O60313-1.3	L30M	Neutral	0.034
OPA1	O60313-1.3	L30N	Pathogenic	0.549
OPA1	O60313-1.3	L30P	Pathogenic	0.799
OPA1	O60313-1.3	L30Q	Neutral	0.389
OPA1	O60313-1.3	L30R	Neutral	0.227
OPA1	O60313-1.3	L30S	Neutral	0.392
OPA1	O60313-1.3	L30T	Neutral	0.239
OPA1	O60313-1.3	L30V	Neutral	0.086
OPA1	O60313-1.3	L30W	Pathogenic	0.667
OPA1	O60313-1.3	L30Y	Neutral	0.386
OPA1	O60313-1.3	Q31A	Neutral	0.234
OPA1	O60313-1.3	Q31C	Pathogenic	0.597
OPA1	O60313-1.3	Q31D	Neutral	0.101
OPA1	O60313-1.3	Q31E	Neutral	0.016
OPA1	O60313-1.3	Q31F	Neutral	0.421
OPA1	O60313-1.3	Q31G	Pathogenic	0.522
OPA1	O60313-1.3	Q31H	Neutral	0.127
OPA1	O60313-1.3	Q31I	Neutral	0.428
OPA1	O60313-1.3	Q31K	Neutral	0.031
OPA1	O60313-1.3	Q31L	Neutral	0.221
OPA1	O60313-1.3	Q31M	Neutral	0.049
OPA1	O60313-1.3	Q31N	Neutral	0.118
OPA1	O60313-1.3	Q31P	Neutral	0.186
OPA1	O60313-1.3	Q31R	Neutral	0.029
OPA1	O60313-1.3	Q31S	Neutral	0.128
OPA1	O60313-1.3	Q31T	Neutral	0.26
OPA1	O60313-1.3	Q31V	Neutral	0.307
OPA1	O60313-1.3	Q31W	Neutral	0.129
OPA1	O60313-1.3	Q31Y	Neutral	0.153
OPA1	O60313-1.3	K32A	Neutral	0.022
OPA1	O60313-1.3	K32C	Neutral	0.1
OPA1	O60313-1.3	K32D	Neutral	0.063
OPA1	O60313-1.3	K32E	Neutral	0.008
OPA1	O60313-1.3	K32F	Neutral	0.06
OPA1	O60313-1.3	K32G	Neutral	0.076
OPA1	O60313-1.3	K32H	Neutral	0.032
OPA1	O60313-1.3	K32I	Neutral	0.057
OPA1	O60313-1.3	K32L	Neutral	0.022
OPA1	O60313-1.3	K32M	Neutral	0.012
OPA1	O60313-1.3	K32N	Neutral	0.02
OPA1	O60313-1.3	K32P	Neutral	0.017
OPA1	O60313-1.3	K32Q	Neutral	0.005
OPA1	O60313-1.3	K32R	Neutral	0.004
OPA1	O60313-1.3	K32S	Neutral	0.011
OPA1	O60313-1.3	K32T	Neutral	0.026
OPA1	O60313-1.3	K32V	Neutral	0.032
OPA1	O60313-1.3	K32W	Neutral	0.036
OPA1	O60313-1.3	K32Y	Neutral	0.044
OPA1	O60313-1.3	L33A	Neutral	0.1
OPA1	O60313-1.3	L33C	Neutral	0.18
OPA1	O60313-1.3	L33D	Pathogenic	0.524
OPA1	O60313-1.3	L33E	Neutral	0.314
OPA1	O60313-1.3	L33F	Neutral	0.13
OPA1	O60313-1.3	L33G	Pathogenic	0.654
OPA1	O60313-1.3	L33H	Neutral	0.489
OPA1	O60313-1.3	L33I	Neutral	0.018
OPA1	O60313-1.3	L33K	Neutral	0.104
OPA1	O60313-1.3	L33M	Neutral	0.013
OPA1	O60313-1.3	L33N	Neutral	0.311
OPA1	O60313-1.3	L33P	Pathogenic	0.596
OPA1	O60313-1.3	L33Q	Neutral	0.191
OPA1	O60313-1.3	L33R	Neutral	0.098
OPA1	O60313-1.3	L33S	Neutral	0.193
OPA1	O60313-1.3	L33T	Neutral	0.104
OPA1	O60313-1.3	L33V	Neutral	0.034
OPA1	O60313-1.3	L33W	Neutral	0.426
OPA1	O60313-1.3	L33Y	Neutral	0.189
OPA1	O60313-1.3	H34A	Neutral	0.49
OPA1	O60313-1.3	H34C	Pathogenic	0.617
OPA1	O60313-1.3	H34D	Neutral	0.157
OPA1	O60313-1.3	H34E	Neutral	0.072
OPA1	O60313-1.3	H34F	Neutral	0.088
OPA1	O60313-1.3	H34G	Neutral	0.482
OPA1	O60313-1.3	H34I	Neutral	0.456
OPA1	O60313-1.3	H34K	Neutral	0.137
OPA1	O60313-1.3	H34L	Neutral	0.48
OPA1	O60313-1.3	H34M	Neutral	0.328
OPA1	O60313-1.3	H34N	Neutral	0.026
OPA1	O60313-1.3	H34P	Neutral	0.418
OPA1	O60313-1.3	H34Q	Neutral	0.104
OPA1	O60313-1.3	H34R	Neutral	0.049
OPA1	O60313-1.3	H34S	Neutral	0.255
OPA1	O60313-1.3	H34T	Pathogenic	0.526
OPA1	O60313-1.3	H34V	Pathogenic	0.583
OPA1	O60313-1.3	H34W	Neutral	0.142
OPA1	O60313-1.3	H34Y	Neutral	0.008
OPA1	O60313-1.3	L35A	Neutral	0.343
OPA1	O60313-1.3	L35C	Pathogenic	0.51
OPA1	O60313-1.3	L35D	Pathogenic	0.838
OPA1	O60313-1.3	L35E	Pathogenic	0.684
OPA1	O60313-1.3	L35F	Neutral	0.414
OPA1	O60313-1.3	L35G	Pathogenic	0.899
OPA1	O60313-1.3	L35H	Pathogenic	0.819
OPA1	O60313-1.3	L35I	Neutral	0.079
OPA1	O60313-1.3	L35K	Neutral	0.354
OPA1	O60313-1.3	L35M	Neutral	0.058
OPA1	O60313-1.3	L35N	Pathogenic	0.68
OPA1	O60313-1.3	L35P	Pathogenic	0.874
OPA1	O60313-1.3	L35Q	Pathogenic	0.527
OPA1	O60313-1.3	L35R	Neutral	0.34
OPA1	O60313-1.3	L35S	Pathogenic	0.53
OPA1	O60313-1.3	L35T	Neutral	0.354
OPA1	O60313-1.3	L35V	Neutral	0.141
OPA1	O60313-1.3	L35W	Pathogenic	0.778
OPA1	O60313-1.3	L35Y	Pathogenic	0.524
OPA1	O60313-1.3	V36A	Neutral	0.041
OPA1	O60313-1.3	V36C	Neutral	0.196
OPA1	O60313-1.3	V36D	Neutral	0.296
OPA1	O60313-1.3	V36E	Neutral	0.145
OPA1	O60313-1.3	V36F	Neutral	0.147
OPA1	O60313-1.3	V36G	Neutral	0.42
OPA1	O60313-1.3	V36H	Neutral	0.49
OPA1	O60313-1.3	V36I	Neutral	0.002
OPA1	O60313-1.3	V36K	Neutral	0.1
OPA1	O60313-1.3	V36L	Neutral	0.023
OPA1	O60313-1.3	V36M	Neutral	0.034
OPA1	O60313-1.3	V36N	Neutral	0.333
OPA1	O60313-1.3	V36P	Neutral	0.36
OPA1	O60313-1.3	V36Q	Neutral	0.196
OPA1	O60313-1.3	V36R	Neutral	0.233
OPA1	O60313-1.3	V36S	Neutral	0.209
OPA1	O60313-1.3	V36T	Neutral	0.043
OPA1	O60313-1.3	V36W	Neutral	0.46
OPA1	O60313-1.3	V36Y	Neutral	0.183
OPA1	O60313-1.3	S37A	Neutral	0.186
OPA1	O60313-1.3	S37C	Pathogenic	0.503
OPA1	O60313-1.3	S37D	Neutral	0.308
OPA1	O60313-1.3	S37E	Neutral	0.319
OPA1	O60313-1.3	S37F	Pathogenic	0.538
OPA1	O60313-1.3	S37G	Neutral	0.45
OPA1	O60313-1.3	S37H	Pathogenic	0.661
OPA1	O60313-1.3	S37I	Pathogenic	0.545
OPA1	O60313-1.3	S37K	Neutral	0.236
OPA1	O60313-1.3	S37L	Pathogenic	0.568
OPA1	O60313-1.3	S37M	Neutral	0.411
OPA1	O60313-1.3	S37N	Neutral	0.149
OPA1	O60313-1.3	S37P	Pathogenic	0.559
OPA1	O60313-1.3	S37Q	Neutral	0.403
OPA1	O60313-1.3	S37R	Neutral	0.457
OPA1	O60313-1.3	S37T	Neutral	0.185
OPA1	O60313-1.3	S37V	Pathogenic	0.688
OPA1	O60313-1.3	S37W	Pathogenic	0.666
OPA1	O60313-1.3	S37Y	Pathogenic	0.709
OPA1	O60313-1.3	R38A	Neutral	0.194
OPA1	O60313-1.3	R38C	Pathogenic	0.539
OPA1	O60313-1.3	R38D	Pathogenic	0.671
OPA1	O60313-1.3	R38E	Neutral	0.187
OPA1	O60313-1.3	R38F	Neutral	0.401
OPA1	O60313-1.3	R38G	Neutral	0.462
OPA1	O60313-1.3	R38H	Neutral	0.105
OPA1	O60313-1.3	R38I	Neutral	0.388
OPA1	O60313-1.3	R38K	Neutral	0.04
OPA1	O60313-1.3	R38L	Neutral	0.194
OPA1	O60313-1.3	R38M	Neutral	0.113
OPA1	O60313-1.3	R38N	Neutral	0.175
OPA1	O60313-1.3	R38P	Neutral	0.343
OPA1	O60313-1.3	R38Q	Neutral	0.052
OPA1	O60313-1.3	R38S	Neutral	0.252
OPA1	O60313-1.3	R38T	Neutral	0.217
OPA1	O60313-1.3	R38V	Pathogenic	0.503
OPA1	O60313-1.3	R38W	Neutral	0.304
OPA1	O60313-1.3	R38Y	Neutral	0.336
OPA1	O60313-1.3	S39A	Neutral	0.017
OPA1	O60313-1.3	S39C	Neutral	0.073
OPA1	O60313-1.3	S39D	Neutral	0.033
OPA1	O60313-1.3	S39E	Neutral	0.035
OPA1	O60313-1.3	S39F	Neutral	0.083
OPA1	O60313-1.3	S39G	Neutral	0.06
OPA1	O60313-1.3	S39H	Neutral	0.132
OPA1	O60313-1.3	S39I	Neutral	0.085
OPA1	O60313-1.3	S39K	Neutral	0.023
OPA1	O60313-1.3	S39L	Neutral	0.093
OPA1	O60313-1.3	S39M	Neutral	0.052
OPA1	O60313-1.3	S39N	Neutral	0.013
OPA1	O60313-1.3	S39P	Neutral	0.09
OPA1	O60313-1.3	S39Q	Neutral	0.05
OPA1	O60313-1.3	S39R	Neutral	0.061
OPA1	O60313-1.3	S39T	Neutral	0.017
OPA1	O60313-1.3	S39V	Neutral	0.146
OPA1	O60313-1.3	S39W	Neutral	0.134
OPA1	O60313-1.3	S39Y	Neutral	0.159
OPA1	O60313-1.3	I40A	Neutral	0.112
OPA1	O60313-1.3	I40C	Neutral	0.201
OPA1	O60313-1.3	I40D	Neutral	0.302
OPA1	O60313-1.3	I40E	Neutral	0.343
OPA1	O60313-1.3	I40F	Neutral	0.167
OPA1	O60313-1.3	I40G	Pathogenic	0.684
OPA1	O60313-1.3	I40H	Pathogenic	0.522
OPA1	O60313-1.3	I40K	Neutral	0.278
OPA1	O60313-1.3	I40L	Neutral	0.022
OPA1	O60313-1.3	I40M	Neutral	0.041
OPA1	O60313-1.3	I40N	Neutral	0.34
OPA1	O60313-1.3	I40P	Pathogenic	0.627
OPA1	O60313-1.3	I40Q	Neutral	0.438
OPA1	O60313-1.3	I40R	Neutral	0.265
OPA1	O60313-1.3	I40S	Neutral	0.215
OPA1	O60313-1.3	I40T	Neutral	0.117
OPA1	O60313-1.3	I40V	Neutral	0.005
OPA1	O60313-1.3	I40W	Pathogenic	0.748
OPA1	O60313-1.3	I40Y	Neutral	0.21
OPA1	O60313-1.3	Y41A	Neutral	0.062
OPA1	O60313-1.3	Y41C	Neutral	0.111
OPA1	O60313-1.3	Y41D	Neutral	0.072
OPA1	O60313-1.3	Y41E	Neutral	0.031
OPA1	O60313-1.3	Y41F	Neutral	0.0
OPA1	O60313-1.3	Y41G	Neutral	0.118
OPA1	O60313-1.3	Y41H	Neutral	0.001
OPA1	O60313-1.3	Y41I	Neutral	0.023
OPA1	O60313-1.3	Y41K	Neutral	0.025
OPA1	O60313-1.3	Y41L	Neutral	0.025
OPA1	O60313-1.3	Y41M	Neutral	0.038
OPA1	O60313-1.3	Y41N	Neutral	0.031
OPA1	O60313-1.3	Y41P	Neutral	0.232
OPA1	O60313-1.3	Y41Q	Neutral	0.016
OPA1	O60313-1.3	Y41R	Neutral	0.025
OPA1	O60313-1.3	Y41S	Neutral	0.047
OPA1	O60313-1.3	Y41T	Neutral	0.064
OPA1	O60313-1.3	Y41V	Neutral	0.036
OPA1	O60313-1.3	Y41W	Neutral	0.001
OPA1	O60313-1.3	H42A	Neutral	0.471
OPA1	O60313-1.3	H42C	Pathogenic	0.599
OPA1	O60313-1.3	H42D	Neutral	0.148
OPA1	O60313-1.3	H42E	Neutral	0.067
OPA1	O60313-1.3	H42F	Neutral	0.083
OPA1	O60313-1.3	H42G	Neutral	0.464
OPA1	O60313-1.3	H42I	Neutral	0.438
OPA1	O60313-1.3	H42K	Neutral	0.128
OPA1	O60313-1.3	H42L	Neutral	0.461
OPA1	O60313-1.3	H42M	Neutral	0.312
OPA1	O60313-1.3	H42N	Neutral	0.024
OPA1	O60313-1.3	H42P	Neutral	0.4
OPA1	O60313-1.3	H42Q	Neutral	0.097
OPA1	O60313-1.3	H42R	Neutral	0.045
OPA1	O60313-1.3	H42S	Neutral	0.24
OPA1	O60313-1.3	H42T	Pathogenic	0.507
OPA1	O60313-1.3	H42V	Pathogenic	0.565
OPA1	O60313-1.3	H42W	Neutral	0.133
OPA1	O60313-1.3	H42Y	Neutral	0.008
OPA1	O60313-1.3	S43A	Neutral	0.001
OPA1	O60313-1.3	S43C	Neutral	0.003
OPA1	O60313-1.3	S43D	Neutral	0.001
OPA1	O60313-1.3	S43E	Neutral	0.001
OPA1	O60313-1.3	S43F	Neutral	0.004
OPA1	O60313-1.3	S43G	Neutral	0.003
OPA1	O60313-1.3	S43H	Neutral	0.006
OPA1	O60313-1.3	S43I	Neutral	0.004
OPA1	O60313-1.3	S43K	Neutral	0.001
OPA1	O60313-1.3	S43L	Neutral	0.004
OPA1	O60313-1.3	S43M	Neutral	0.002
OPA1	O60313-1.3	S43N	Neutral	0.001
OPA1	O60313-1.3	S43P	Neutral	0.004
OPA1	O60313-1.3	S43Q	Neutral	0.002
OPA1	O60313-1.3	S43R	Neutral	0.003
OPA1	O60313-1.3	S43T	Neutral	0.001
OPA1	O60313-1.3	S43V	Neutral	0.007
OPA1	O60313-1.3	S43W	Neutral	0.006
OPA1	O60313-1.3	S43Y	Neutral	0.008
OPA1	O60313-1.3	H44A	Neutral	0.065
OPA1	O60313-1.3	H44C	Neutral	0.104
OPA1	O60313-1.3	H44D	Neutral	0.013
OPA1	O60313-1.3	H44E	Neutral	0.006
OPA1	O60313-1.3	H44F	Neutral	0.007
OPA1	O60313-1.3	H44G	Neutral	0.063
OPA1	O60313-1.3	H44I	Neutral	0.057
OPA1	O60313-1.3	H44K	Neutral	0.011
OPA1	O60313-1.3	H44L	Neutral	0.062
OPA1	O60313-1.3	H44M	Neutral	0.034
OPA1	O60313-1.3	H44N	Neutral	0.002
OPA1	O60313-1.3	H44P	Neutral	0.049
OPA1	O60313-1.3	H44Q	Neutral	0.008
OPA1	O60313-1.3	H44R	Neutral	0.004
OPA1	O60313-1.3	H44S	Neutral	0.024
OPA1	O60313-1.3	H44T	Neutral	0.074
OPA1	O60313-1.3	H44V	Neutral	0.091
OPA1	O60313-1.3	H44W	Neutral	0.012
OPA1	O60313-1.3	H44Y	Neutral	0.001
OPA1	O60313-1.3	H45A	Neutral	0.075
OPA1	O60313-1.3	H45C	Neutral	0.119
OPA1	O60313-1.3	H45D	Neutral	0.015
OPA1	O60313-1.3	H45E	Neutral	0.006
OPA1	O60313-1.3	H45F	Neutral	0.008
OPA1	O60313-1.3	H45G	Neutral	0.073
OPA1	O60313-1.3	H45I	Neutral	0.066
OPA1	O60313-1.3	H45K	Neutral	0.013
OPA1	O60313-1.3	H45L	Neutral	0.072
OPA1	O60313-1.3	H45M	Neutral	0.039
OPA1	O60313-1.3	H45N	Neutral	0.002
OPA1	O60313-1.3	H45P	Neutral	0.057
OPA1	O60313-1.3	H45Q	Neutral	0.01
OPA1	O60313-1.3	H45R	Neutral	0.004
OPA1	O60313-1.3	H45S	Neutral	0.028
OPA1	O60313-1.3	H45T	Neutral	0.085
OPA1	O60313-1.3	H45V	Neutral	0.105
OPA1	O60313-1.3	H45W	Neutral	0.014
OPA1	O60313-1.3	H45Y	Neutral	0.001
OPA1	O60313-1.3	P46A	Neutral	0.082
OPA1	O60313-1.3	P46C	Neutral	0.48
OPA1	O60313-1.3	P46D	Neutral	0.035
OPA1	O60313-1.3	P46E	Neutral	0.037
OPA1	O60313-1.3	P46F	Pathogenic	0.524
OPA1	O60313-1.3	P46G	Neutral	0.154
OPA1	O60313-1.3	P46H	Neutral	0.178
OPA1	O60313-1.3	P46I	Neutral	0.281
OPA1	O60313-1.3	P46K	Neutral	0.025
OPA1	O60313-1.3	P46L	Neutral	0.3
OPA1	O60313-1.3	P46M	Neutral	0.185
OPA1	O60313-1.3	P46N	Neutral	0.108
OPA1	O60313-1.3	P46Q	Neutral	0.052
OPA1	O60313-1.3	P46R	Neutral	0.064
OPA1	O60313-1.3	P46S	Neutral	0.063
OPA1	O60313-1.3	P46T	Neutral	0.084
OPA1	O60313-1.3	P46V	Neutral	0.198
OPA1	O60313-1.3	P46W	Neutral	0.394
OPA1	O60313-1.3	P46Y	Neutral	0.442
OPA1	O60313-1.3	T47A	Neutral	0.001
OPA1	O60313-1.3	T47C	Neutral	0.002
OPA1	O60313-1.3	T47D	Neutral	0.001
OPA1	O60313-1.3	T47E	Neutral	0.001
OPA1	O60313-1.3	T47F	Neutral	0.002
OPA1	O60313-1.3	T47G	Neutral	0.007
OPA1	O60313-1.3	T47H	Neutral	0.008
OPA1	O60313-1.3	T47I	Neutral	0.001
OPA1	O60313-1.3	T47K	Neutral	0.001
OPA1	O60313-1.3	T47L	Neutral	0.001
OPA1	O60313-1.3	T47M	Neutral	0.001
OPA1	O60313-1.3	T47N	Neutral	0.001
OPA1	O60313-1.3	T47P	Neutral	0.002
OPA1	O60313-1.3	T47Q	Neutral	0.002
OPA1	O60313-1.3	T47R	Neutral	0.001
OPA1	O60313-1.3	T47S	Neutral	0.0
OPA1	O60313-1.3	T47V	Neutral	0.0
OPA1	O60313-1.3	T47W	Neutral	0.001
OPA1	O60313-1.3	T47Y	Neutral	0.004
OPA1	O60313-1.3	L48A	Neutral	0.001
OPA1	O60313-1.3	L48C	Neutral	0.002
OPA1	O60313-1.3	L48D	Neutral	0.009
OPA1	O60313-1.3	L48E	Neutral	0.004
OPA1	O60313-1.3	L48F	Neutral	0.001
OPA1	O60313-1.3	L48G	Neutral	0.015
OPA1	O60313-1.3	L48H	Neutral	0.008
OPA1	O60313-1.3	L48I	Neutral	0.0
OPA1	O60313-1.3	L48K	Neutral	0.001
OPA1	O60313-1.3	L48M	Neutral	0.0
OPA1	O60313-1.3	L48N	Neutral	0.004
OPA1	O60313-1.3	L48P	Neutral	0.012
OPA1	O60313-1.3	L48Q	Neutral	0.002
OPA1	O60313-1.3	L48R	Neutral	0.001
OPA1	O60313-1.3	L48S	Neutral	0.002
OPA1	O60313-1.3	L48T	Neutral	0.001
OPA1	O60313-1.3	L48V	Neutral	0.0
OPA1	O60313-1.3	L48W	Neutral	0.006
OPA1	O60313-1.3	L48Y	Neutral	0.002
OPA1	O60313-1.3	K49A	Neutral	0.026
OPA1	O60313-1.3	K49C	Neutral	0.117
OPA1	O60313-1.3	K49D	Neutral	0.074
OPA1	O60313-1.3	K49E	Neutral	0.009
OPA1	O60313-1.3	K49F	Neutral	0.071
OPA1	O60313-1.3	K49G	Neutral	0.089
OPA1	O60313-1.3	K49H	Neutral	0.037
OPA1	O60313-1.3	K49I	Neutral	0.067
OPA1	O60313-1.3	K49L	Neutral	0.027
OPA1	O60313-1.3	K49M	Neutral	0.014
OPA1	O60313-1.3	K49N	Neutral	0.023
OPA1	O60313-1.3	K49P	Neutral	0.02
OPA1	O60313-1.3	K49Q	Neutral	0.006
OPA1	O60313-1.3	K49R	Neutral	0.004
OPA1	O60313-1.3	K49S	Neutral	0.013
OPA1	O60313-1.3	K49T	Neutral	0.03
OPA1	O60313-1.3	K49V	Neutral	0.038
OPA1	O60313-1.3	K49W	Neutral	0.043
OPA1	O60313-1.3	K49Y	Neutral	0.052
OPA1	O60313-1.3	L50A	Neutral	0.001
OPA1	O60313-1.3	L50C	Neutral	0.003
OPA1	O60313-1.3	L50D	Neutral	0.014
OPA1	O60313-1.3	L50E	Neutral	0.006
OPA1	O60313-1.3	L50F	Neutral	0.002
OPA1	O60313-1.3	L50G	Neutral	0.024
OPA1	O60313-1.3	L50H	Neutral	0.012
OPA1	O60313-1.3	L50I	Neutral	0.0
OPA1	O60313-1.3	L50K	Neutral	0.002
OPA1	O60313-1.3	L50M	Neutral	0.0
OPA1	O60313-1.3	L50N	Neutral	0.006
OPA1	O60313-1.3	L50P	Neutral	0.019
OPA1	O60313-1.3	L50Q	Neutral	0.003
OPA1	O60313-1.3	L50R	Neutral	0.001
OPA1	O60313-1.3	L50S	Neutral	0.003
OPA1	O60313-1.3	L50T	Neutral	0.002
OPA1	O60313-1.3	L50V	Neutral	0.0
OPA1	O60313-1.3	L50W	Neutral	0.01
OPA1	O60313-1.3	L50Y	Neutral	0.003
OPA1	O60313-1.3	Q51A	Neutral	0.052
OPA1	O60313-1.3	Q51C	Neutral	0.211
OPA1	O60313-1.3	Q51D	Neutral	0.02
OPA1	O60313-1.3	Q51E	Neutral	0.003
OPA1	O60313-1.3	Q51F	Neutral	0.116
OPA1	O60313-1.3	Q51G	Neutral	0.164
OPA1	O60313-1.3	Q51H	Neutral	0.025
OPA1	O60313-1.3	Q51I	Neutral	0.119
OPA1	O60313-1.3	Q51K	Neutral	0.006
OPA1	O60313-1.3	Q51L	Neutral	0.049
OPA1	O60313-1.3	Q51M	Neutral	0.009
OPA1	O60313-1.3	Q51N	Neutral	0.024
OPA1	O60313-1.3	Q51P	Neutral	0.039
OPA1	O60313-1.3	Q51R	Neutral	0.005
OPA1	O60313-1.3	Q51S	Neutral	0.026
OPA1	O60313-1.3	Q51T	Neutral	0.06
OPA1	O60313-1.3	Q51V	Neutral	0.074
OPA1	O60313-1.3	Q51W	Neutral	0.026
OPA1	O60313-1.3	Q51Y	Neutral	0.032
OPA1	O60313-1.3	R52A	Neutral	0.226
OPA1	O60313-1.3	R52C	Pathogenic	0.587
OPA1	O60313-1.3	R52D	Pathogenic	0.713
OPA1	O60313-1.3	R52E	Neutral	0.219
OPA1	O60313-1.3	R52F	Neutral	0.449
OPA1	O60313-1.3	R52G	Pathogenic	0.511
OPA1	O60313-1.3	R52H	Neutral	0.125
OPA1	O60313-1.3	R52I	Neutral	0.436
OPA1	O60313-1.3	R52K	Neutral	0.048
OPA1	O60313-1.3	R52L	Neutral	0.226
OPA1	O60313-1.3	R52M	Neutral	0.134
OPA1	O60313-1.3	R52N	Neutral	0.205
OPA1	O60313-1.3	R52P	Neutral	0.388
OPA1	O60313-1.3	R52Q	Neutral	0.063
OPA1	O60313-1.3	R52S	Neutral	0.29
OPA1	O60313-1.3	R52T	Neutral	0.252
OPA1	O60313-1.3	R52V	Pathogenic	0.552
OPA1	O60313-1.3	R52W	Neutral	0.347
OPA1	O60313-1.3	R52Y	Neutral	0.381
OPA1	O60313-1.3	P53A	Neutral	0.122
OPA1	O60313-1.3	P53C	Pathogenic	0.589
OPA1	O60313-1.3	P53D	Neutral	0.053
OPA1	O60313-1.3	P53E	Neutral	0.056
OPA1	O60313-1.3	P53F	Pathogenic	0.63
OPA1	O60313-1.3	P53G	Neutral	0.22
OPA1	O60313-1.3	P53H	Neutral	0.251
OPA1	O60313-1.3	P53I	Neutral	0.376
OPA1	O60313-1.3	P53K	Neutral	0.037
OPA1	O60313-1.3	P53L	Neutral	0.398
OPA1	O60313-1.3	P53M	Neutral	0.26
OPA1	O60313-1.3	P53N	Neutral	0.157
OPA1	O60313-1.3	P53Q	Neutral	0.078
OPA1	O60313-1.3	P53R	Neutral	0.096
OPA1	O60313-1.3	P53S	Neutral	0.094
OPA1	O60313-1.3	P53T	Neutral	0.125
OPA1	O60313-1.3	P53V	Neutral	0.276
OPA1	O60313-1.3	P53W	Pathogenic	0.501
OPA1	O60313-1.3	P53Y	Pathogenic	0.55
OPA1	O60313-1.3	Q54A	Neutral	0.018
OPA1	O60313-1.3	Q54C	Neutral	0.084
OPA1	O60313-1.3	Q54D	Neutral	0.007
OPA1	O60313-1.3	Q54E	Neutral	0.001
OPA1	O60313-1.3	Q54F	Neutral	0.043
OPA1	O60313-1.3	Q54G	Neutral	0.063
OPA1	O60313-1.3	Q54H	Neutral	0.009
OPA1	O60313-1.3	Q54I	Neutral	0.044
OPA1	O60313-1.3	Q54K	Neutral	0.002
OPA1	O60313-1.3	Q54L	Neutral	0.017
OPA1	O60313-1.3	Q54M	Neutral	0.003
OPA1	O60313-1.3	Q54N	Neutral	0.008
OPA1	O60313-1.3	Q54P	Neutral	0.014
OPA1	O60313-1.3	Q54R	Neutral	0.002
OPA1	O60313-1.3	Q54S	Neutral	0.009
OPA1	O60313-1.3	Q54T	Neutral	0.021
OPA1	O60313-1.3	Q54V	Neutral	0.027
OPA1	O60313-1.3	Q54W	Neutral	0.009
OPA1	O60313-1.3	Q54Y	Neutral	0.011
OPA1	O60313-1.3	L55A	Neutral	0.005
OPA1	O60313-1.3	L55C	Neutral	0.01
OPA1	O60313-1.3	L55D	Neutral	0.046
OPA1	O60313-1.3	L55E	Neutral	0.02
OPA1	O60313-1.3	L55F	Neutral	0.007
OPA1	O60313-1.3	L55G	Neutral	0.077
OPA1	O60313-1.3	L55H	Neutral	0.04
OPA1	O60313-1.3	L55I	Neutral	0.001
OPA1	O60313-1.3	L55K	Neutral	0.005
OPA1	O60313-1.3	L55M	Neutral	0.001
OPA1	O60313-1.3	L55N	Neutral	0.019
OPA1	O60313-1.3	L55P	Neutral	0.061
OPA1	O60313-1.3	L55Q	Neutral	0.01
OPA1	O60313-1.3	L55R	Neutral	0.005
OPA1	O60313-1.3	L55S	Neutral	0.01
OPA1	O60313-1.3	L55T	Neutral	0.005
OPA1	O60313-1.3	L55V	Neutral	0.002
OPA1	O60313-1.3	L55W	Neutral	0.032
OPA1	O60313-1.3	L55Y	Neutral	0.01
OPA1	O60313-1.3	R56A	Neutral	0.021
OPA1	O60313-1.3	R56C	Neutral	0.095
OPA1	O60313-1.3	R56D	Neutral	0.155
OPA1	O60313-1.3	R56E	Neutral	0.02
OPA1	O60313-1.3	R56F	Neutral	0.057
OPA1	O60313-1.3	R56G	Neutral	0.072
OPA1	O60313-1.3	R56H	Neutral	0.01
OPA1	O60313-1.3	R56I	Neutral	0.054
OPA1	O60313-1.3	R56K	Neutral	0.004
OPA1	O60313-1.3	R56L	Neutral	0.021
OPA1	O60313-1.3	R56M	Neutral	0.011
OPA1	O60313-1.3	R56N	Neutral	0.019
OPA1	O60313-1.3	R56P	Neutral	0.045
OPA1	O60313-1.3	R56Q	Neutral	0.005
OPA1	O60313-1.3	R56S	Neutral	0.029
OPA1	O60313-1.3	R56T	Neutral	0.024
OPA1	O60313-1.3	R56V	Neutral	0.083
OPA1	O60313-1.3	R56W	Neutral	0.038
OPA1	O60313-1.3	R56Y	Neutral	0.043
OPA1	O60313-1.3	T57A	Neutral	0.003
OPA1	O60313-1.3	T57C	Neutral	0.005
OPA1	O60313-1.3	T57D	Neutral	0.004
OPA1	O60313-1.3	T57E	Neutral	0.004
OPA1	O60313-1.3	T57F	Neutral	0.006
OPA1	O60313-1.3	T57G	Neutral	0.018
OPA1	O60313-1.3	T57H	Neutral	0.022
OPA1	O60313-1.3	T57I	Neutral	0.002
OPA1	O60313-1.3	T57K	Neutral	0.003
OPA1	O60313-1.3	T57L	Neutral	0.002
OPA1	O60313-1.3	T57M	Neutral	0.003
OPA1	O60313-1.3	T57N	Neutral	0.001
OPA1	O60313-1.3	T57P	Neutral	0.006
OPA1	O60313-1.3	T57Q	Neutral	0.006
OPA1	O60313-1.3	T57R	Neutral	0.002
OPA1	O60313-1.3	T57S	Neutral	0.001
OPA1	O60313-1.3	T57V	Neutral	0.001
OPA1	O60313-1.3	T57W	Neutral	0.003
OPA1	O60313-1.3	T57Y	Neutral	0.012
OPA1	O60313-1.3	S58A	Neutral	0.007
OPA1	O60313-1.3	S58C	Neutral	0.03
OPA1	O60313-1.3	S58D	Neutral	0.014
OPA1	O60313-1.3	S58E	Neutral	0.014
OPA1	O60313-1.3	S58F	Neutral	0.035
OPA1	O60313-1.3	S58G	Neutral	0.025
OPA1	O60313-1.3	S58H	Neutral	0.057
OPA1	O60313-1.3	S58I	Neutral	0.036
OPA1	O60313-1.3	S58K	Neutral	0.01
OPA1	O60313-1.3	S58L	Neutral	0.039
OPA1	O60313-1.3	S58M	Neutral	0.021
OPA1	O60313-1.3	S58N	Neutral	0.005
OPA1	O60313-1.3	S58P	Neutral	0.038
OPA1	O60313-1.3	S58Q	Neutral	0.021
OPA1	O60313-1.3	S58R	Neutral	0.025
OPA1	O60313-1.3	S58T	Neutral	0.007
OPA1	O60313-1.3	S58V	Neutral	0.064
OPA1	O60313-1.3	S58W	Neutral	0.058
OPA1	O60313-1.3	S58Y	Neutral	0.07
OPA1	O60313-1.3	F59A	Neutral	0.004
OPA1	O60313-1.3	F59C	Neutral	0.008
OPA1	O60313-1.3	F59D	Neutral	0.005
OPA1	O60313-1.3	F59E	Neutral	0.006
OPA1	O60313-1.3	F59G	Neutral	0.008
OPA1	O60313-1.3	F59H	Neutral	0.001
OPA1	O60313-1.3	F59I	Neutral	0.002
OPA1	O60313-1.3	F59K	Neutral	0.005
OPA1	O60313-1.3	F59L	Neutral	0.002
OPA1	O60313-1.3	F59M	Neutral	0.001
OPA1	O60313-1.3	F59N	Neutral	0.006
OPA1	O60313-1.3	F59P	Neutral	0.053
OPA1	O60313-1.3	F59Q	Neutral	0.009
OPA1	O60313-1.3	F59R	Neutral	0.004
OPA1	O60313-1.3	F59S	Neutral	0.003
OPA1	O60313-1.3	F59T	Neutral	0.004
OPA1	O60313-1.3	F59V	Neutral	0.004
OPA1	O60313-1.3	F59W	Neutral	0.001
OPA1	O60313-1.3	F59Y	Neutral	0.0
OPA1	O60313-1.3	Q60A	Neutral	0.054
OPA1	O60313-1.3	Q60C	Neutral	0.216
OPA1	O60313-1.3	Q60D	Neutral	0.021
OPA1	O60313-1.3	Q60E	Neutral	0.003
OPA1	O60313-1.3	Q60F	Neutral	0.119
OPA1	O60313-1.3	Q60G	Neutral	0.169
OPA1	O60313-1.3	Q60H	Neutral	0.026
OPA1	O60313-1.3	Q60I	Neutral	0.122
OPA1	O60313-1.3	Q60K	Neutral	0.006
OPA1	O60313-1.3	Q60L	Neutral	0.05
OPA1	O60313-1.3	Q60M	Neutral	0.01
OPA1	O60313-1.3	Q60N	Neutral	0.024
OPA1	O60313-1.3	Q60P	Neutral	0.041
OPA1	O60313-1.3	Q60R	Neutral	0.006
OPA1	O60313-1.3	Q60S	Neutral	0.027
OPA1	O60313-1.3	Q60T	Neutral	0.061
OPA1	O60313-1.3	Q60V	Neutral	0.076
OPA1	O60313-1.3	Q60W	Neutral	0.027
OPA1	O60313-1.3	Q60Y	Neutral	0.032
OPA1	O60313-1.3	Q61A	Neutral	0.003
OPA1	O60313-1.3	Q61C	Neutral	0.015
OPA1	O60313-1.3	Q61D	Neutral	0.001
OPA1	O60313-1.3	Q61E	Neutral	0.0
OPA1	O60313-1.3	Q61F	Neutral	0.007
OPA1	O60313-1.3	Q61G	Neutral	0.011
OPA1	O60313-1.3	Q61H	Neutral	0.001
OPA1	O60313-1.3	Q61I	Neutral	0.008
OPA1	O60313-1.3	Q61K	Neutral	0.0
OPA1	O60313-1.3	Q61L	Neutral	0.003
OPA1	O60313-1.3	Q61M	Neutral	0.001
OPA1	O60313-1.3	Q61N	Neutral	0.001
OPA1	O60313-1.3	Q61P	Neutral	0.002
OPA1	O60313-1.3	Q61R	Neutral	0.0
OPA1	O60313-1.3	Q61S	Neutral	0.002
OPA1	O60313-1.3	Q61T	Neutral	0.004
OPA1	O60313-1.3	Q61V	Neutral	0.005
OPA1	O60313-1.3	Q61W	Neutral	0.002
OPA1	O60313-1.3	Q61Y	Neutral	0.002
OPA1	O60313-1.3	F62A	Neutral	0.298
OPA1	O60313-1.3	F62C	Neutral	0.458
OPA1	O60313-1.3	F62D	Neutral	0.335
OPA1	O60313-1.3	F62E	Neutral	0.378
OPA1	O60313-1.3	F62G	Neutral	0.464
OPA1	O60313-1.3	F62H	Neutral	0.131
OPA1	O60313-1.3	F62I	Neutral	0.193
OPA1	O60313-1.3	F62K	Neutral	0.326
OPA1	O60313-1.3	F62L	Neutral	0.183
OPA1	O60313-1.3	F62M	Neutral	0.127
OPA1	O60313-1.3	F62N	Neutral	0.374
OPA1	O60313-1.3	F62P	Pathogenic	0.85
OPA1	O60313-1.3	F62Q	Neutral	0.475
OPA1	O60313-1.3	F62R	Neutral	0.313
OPA1	O60313-1.3	F62S	Neutral	0.241
OPA1	O60313-1.3	F62T	Neutral	0.309
OPA1	O60313-1.3	F62V	Neutral	0.28
OPA1	O60313-1.3	F62W	Neutral	0.049
OPA1	O60313-1.3	F62Y	Neutral	0.005
OPA1	O60313-1.3	S63A	Neutral	0.035
OPA1	O60313-1.3	S63C	Neutral	0.137
OPA1	O60313-1.3	S63D	Neutral	0.065
OPA1	O60313-1.3	S63E	Neutral	0.069
OPA1	O60313-1.3	S63F	Neutral	0.155
OPA1	O60313-1.3	S63G	Neutral	0.114
OPA1	O60313-1.3	S63H	Neutral	0.235
OPA1	O60313-1.3	S63I	Neutral	0.159
OPA1	O60313-1.3	S63K	Neutral	0.046
OPA1	O60313-1.3	S63L	Neutral	0.172
OPA1	O60313-1.3	S63M	Neutral	0.099
OPA1	O60313-1.3	S63N	Neutral	0.027
OPA1	O60313-1.3	S63P	Neutral	0.166
OPA1	O60313-1.3	S63Q	Neutral	0.096
OPA1	O60313-1.3	S63R	Neutral	0.117
OPA1	O60313-1.3	S63T	Neutral	0.035
OPA1	O60313-1.3	S63V	Neutral	0.257
OPA1	O60313-1.3	S63W	Neutral	0.239
OPA1	O60313-1.3	S63Y	Neutral	0.277
OPA1	O60313-1.3	S64A	Neutral	0.031
OPA1	O60313-1.3	S64C	Neutral	0.124
OPA1	O60313-1.3	S64D	Neutral	0.059
OPA1	O60313-1.3	S64E	Neutral	0.062
OPA1	O60313-1.3	S64F	Neutral	0.14
OPA1	O60313-1.3	S64G	Neutral	0.103
OPA1	O60313-1.3	S64H	Neutral	0.215
OPA1	O60313-1.3	S64I	Neutral	0.144
OPA1	O60313-1.3	S64K	Neutral	0.041
OPA1	O60313-1.3	S64L	Neutral	0.156
OPA1	O60313-1.3	S64M	Neutral	0.089
OPA1	O60313-1.3	S64N	Neutral	0.024
OPA1	O60313-1.3	S64P	Neutral	0.151
OPA1	O60313-1.3	S64Q	Neutral	0.086
OPA1	O60313-1.3	S64R	Neutral	0.105
OPA1	O60313-1.3	S64T	Neutral	0.031
OPA1	O60313-1.3	S64V	Neutral	0.236
OPA1	O60313-1.3	S64W	Neutral	0.218
OPA1	O60313-1.3	S64Y	Neutral	0.254
OPA1	O60313-1.3	L65A	Neutral	0.019
OPA1	O60313-1.3	L65C	Neutral	0.038
OPA1	O60313-1.3	L65D	Neutral	0.164
OPA1	O60313-1.3	L65E	Neutral	0.076
OPA1	O60313-1.3	L65F	Neutral	0.026
OPA1	O60313-1.3	L65G	Neutral	0.253
OPA1	O60313-1.3	L65H	Neutral	0.146
OPA1	O60313-1.3	L65I	Neutral	0.003
OPA1	O60313-1.3	L65K	Neutral	0.02
OPA1	O60313-1.3	L65M	Neutral	0.002
OPA1	O60313-1.3	L65N	Neutral	0.075
OPA1	O60313-1.3	L65P	Neutral	0.209
OPA1	O60313-1.3	L65Q	Neutral	0.04
OPA1	O60313-1.3	L65R	Neutral	0.019
OPA1	O60313-1.3	L65S	Neutral	0.041
OPA1	O60313-1.3	L65T	Neutral	0.02
OPA1	O60313-1.3	L65V	Neutral	0.006
OPA1	O60313-1.3	L65W	Neutral	0.117
OPA1	O60313-1.3	L65Y	Neutral	0.04
OPA1	O60313-1.3	T66A	Neutral	0.003
OPA1	O60313-1.3	T66C	Neutral	0.006
OPA1	O60313-1.3	T66D	Neutral	0.005
OPA1	O60313-1.3	T66E	Neutral	0.005
OPA1	O60313-1.3	T66F	Neutral	0.007
OPA1	O60313-1.3	T66G	Neutral	0.022
OPA1	O60313-1.3	T66H	Neutral	0.027
OPA1	O60313-1.3	T66I	Neutral	0.003
OPA1	O60313-1.3	T66K	Neutral	0.003
OPA1	O60313-1.3	T66L	Neutral	0.003
OPA1	O60313-1.3	T66M	Neutral	0.004
OPA1	O60313-1.3	T66N	Neutral	0.002
OPA1	O60313-1.3	T66P	Neutral	0.008
OPA1	O60313-1.3	T66Q	Neutral	0.007
OPA1	O60313-1.3	T66R	Neutral	0.003
OPA1	O60313-1.3	T66S	Neutral	0.001
OPA1	O60313-1.3	T66V	Neutral	0.002
OPA1	O60313-1.3	T66W	Neutral	0.004
OPA1	O60313-1.3	T66Y	Neutral	0.015
OPA1	O60313-1.3	N67A	Neutral	0.037
OPA1	O60313-1.3	N67C	Neutral	0.061
OPA1	O60313-1.3	N67D	Neutral	0.003
OPA1	O60313-1.3	N67E	Neutral	0.011
OPA1	O60313-1.3	N67F	Neutral	0.027
OPA1	O60313-1.3	N67G	Neutral	0.006
OPA1	O60313-1.3	N67H	Neutral	0.002
OPA1	O60313-1.3	N67I	Neutral	0.028
OPA1	O60313-1.3	N67K	Neutral	0.007
OPA1	O60313-1.3	N67L	Neutral	0.03
OPA1	O60313-1.3	N67M	Neutral	0.016
OPA1	O60313-1.3	N67P	Neutral	0.028
OPA1	O60313-1.3	N67Q	Neutral	0.008
OPA1	O60313-1.3	N67R	Neutral	0.007
OPA1	O60313-1.3	N67S	Neutral	0.002
OPA1	O60313-1.3	N67T	Neutral	0.005
OPA1	O60313-1.3	N67V	Neutral	0.05
OPA1	O60313-1.3	N67W	Neutral	0.045
OPA1	O60313-1.3	N67Y	Neutral	0.02
OPA1	O60313-1.3	L68A	Neutral	0.139
OPA1	O60313-1.3	L68C	Neutral	0.244
OPA1	O60313-1.3	L68D	Pathogenic	0.617
OPA1	O60313-1.3	L68E	Neutral	0.401
OPA1	O60313-1.3	L68F	Neutral	0.18
OPA1	O60313-1.3	L68G	Pathogenic	0.735
OPA1	O60313-1.3	L68H	Pathogenic	0.584
OPA1	O60313-1.3	L68I	Neutral	0.026
OPA1	O60313-1.3	L68K	Neutral	0.145
OPA1	O60313-1.3	L68M	Neutral	0.019
OPA1	O60313-1.3	L68N	Neutral	0.398
OPA1	O60313-1.3	L68P	Pathogenic	0.684
OPA1	O60313-1.3	L68Q	Neutral	0.257
OPA1	O60313-1.3	L68R	Neutral	0.138
OPA1	O60313-1.3	L68S	Neutral	0.259
OPA1	O60313-1.3	L68T	Neutral	0.146
OPA1	O60313-1.3	L68V	Neutral	0.049
OPA1	O60313-1.3	L68W	Pathogenic	0.521
OPA1	O60313-1.3	L68Y	Neutral	0.255
OPA1	O60313-1.3	P69A	Neutral	0.236
OPA1	O60313-1.3	P69C	Pathogenic	0.761
OPA1	O60313-1.3	P69D	Neutral	0.111
OPA1	O60313-1.3	P69E	Neutral	0.116
OPA1	O60313-1.3	P69F	Pathogenic	0.791
OPA1	O60313-1.3	P69G	Neutral	0.386
OPA1	O60313-1.3	P69H	Neutral	0.428
OPA1	O60313-1.3	P69I	Pathogenic	0.573
OPA1	O60313-1.3	P69K	Neutral	0.08
OPA1	O60313-1.3	P69L	Pathogenic	0.596
OPA1	O60313-1.3	P69M	Neutral	0.439
OPA1	O60313-1.3	P69N	Neutral	0.293
OPA1	O60313-1.3	P69Q	Neutral	0.159
OPA1	O60313-1.3	P69R	Neutral	0.191
OPA1	O60313-1.3	P69S	Neutral	0.187
OPA1	O60313-1.3	P69T	Neutral	0.241
OPA1	O60313-1.3	P69V	Neutral	0.46
OPA1	O60313-1.3	P69W	Pathogenic	0.691
OPA1	O60313-1.3	P69Y	Pathogenic	0.732
OPA1	O60313-1.3	L70A	Neutral	0.074
OPA1	O60313-1.3	L70C	Neutral	0.137
OPA1	O60313-1.3	L70D	Neutral	0.441
OPA1	O60313-1.3	L70E	Neutral	0.248
OPA1	O60313-1.3	L70F	Neutral	0.097
OPA1	O60313-1.3	L70G	Pathogenic	0.577
OPA1	O60313-1.3	L70H	Neutral	0.408
OPA1	O60313-1.3	L70I	Neutral	0.013
OPA1	O60313-1.3	L70K	Neutral	0.077
OPA1	O60313-1.3	L70M	Neutral	0.009
OPA1	O60313-1.3	L70N	Neutral	0.245
OPA1	O60313-1.3	L70P	Pathogenic	0.515
OPA1	O60313-1.3	L70Q	Neutral	0.145
OPA1	O60313-1.3	L70R	Neutral	0.073
OPA1	O60313-1.3	L70S	Neutral	0.147
OPA1	O60313-1.3	L70T	Neutral	0.077
OPA1	O60313-1.3	L70V	Neutral	0.024
OPA1	O60313-1.3	L70W	Neutral	0.348
OPA1	O60313-1.3	L70Y	Neutral	0.144
OPA1	O60313-1.3	R71A	Neutral	0.054
OPA1	O60313-1.3	R71C	Neutral	0.219
OPA1	O60313-1.3	R71D	Neutral	0.328
OPA1	O60313-1.3	R71E	Neutral	0.052
OPA1	O60313-1.3	R71F	Neutral	0.138
OPA1	O60313-1.3	R71G	Neutral	0.171
OPA1	O60313-1.3	R71H	Neutral	0.027
OPA1	O60313-1.3	R71I	Neutral	0.132
OPA1	O60313-1.3	R71K	Neutral	0.01
OPA1	O60313-1.3	R71L	Neutral	0.054
OPA1	O60313-1.3	R71M	Neutral	0.03
OPA1	O60313-1.3	R71N	Neutral	0.048
OPA1	O60313-1.3	R71P	Neutral	0.111
OPA1	O60313-1.3	R71Q	Neutral	0.013
OPA1	O60313-1.3	R71S	Neutral	0.075
OPA1	O60313-1.3	R71T	Neutral	0.062
OPA1	O60313-1.3	R71V	Neutral	0.195
OPA1	O60313-1.3	R71W	Neutral	0.095
OPA1	O60313-1.3	R71Y	Neutral	0.108
OPA1	O60313-1.3	K72A	Neutral	0.012
OPA1	O60313-1.3	K72C	Neutral	0.056
OPA1	O60313-1.3	K72D	Neutral	0.034
OPA1	O60313-1.3	K72E	Neutral	0.004
OPA1	O60313-1.3	K72F	Neutral	0.033
OPA1	O60313-1.3	K72G	Neutral	0.041
OPA1	O60313-1.3	K72H	Neutral	0.017
OPA1	O60313-1.3	K72I	Neutral	0.031
OPA1	O60313-1.3	K72L	Neutral	0.012
OPA1	O60313-1.3	K72M	Neutral	0.006
OPA1	O60313-1.3	K72N	Neutral	0.011
OPA1	O60313-1.3	K72P	Neutral	0.009
OPA1	O60313-1.3	K72Q	Neutral	0.003
OPA1	O60313-1.3	K72R	Neutral	0.002
OPA1	O60313-1.3	K72S	Neutral	0.006
OPA1	O60313-1.3	K72T	Neutral	0.014
OPA1	O60313-1.3	K72V	Neutral	0.017
OPA1	O60313-1.3	K72W	Neutral	0.02
OPA1	O60313-1.3	K72Y	Neutral	0.024
OPA1	O60313-1.3	L73A	Neutral	0.005
OPA1	O60313-1.3	L73C	Neutral	0.01
OPA1	O60313-1.3	L73D	Neutral	0.049
OPA1	O60313-1.3	L73E	Neutral	0.021
OPA1	O60313-1.3	L73F	Neutral	0.007
OPA1	O60313-1.3	L73G	Neutral	0.081
OPA1	O60313-1.3	L73H	Neutral	0.043
OPA1	O60313-1.3	L73I	Neutral	0.001
OPA1	O60313-1.3	L73K	Neutral	0.005
OPA1	O60313-1.3	L73M	Neutral	0.001
OPA1	O60313-1.3	L73N	Neutral	0.021
OPA1	O60313-1.3	L73P	Neutral	0.064
OPA1	O60313-1.3	L73Q	Neutral	0.011
OPA1	O60313-1.3	L73R	Neutral	0.005
OPA1	O60313-1.3	L73S	Neutral	0.011
OPA1	O60313-1.3	L73T	Neutral	0.005
OPA1	O60313-1.3	L73V	Neutral	0.002
OPA1	O60313-1.3	L73W	Neutral	0.033
OPA1	O60313-1.3	L73Y	Neutral	0.011
OPA1	O60313-1.3	K74A	Neutral	0.072
OPA1	O60313-1.3	K74C	Neutral	0.275
OPA1	O60313-1.3	K74D	Neutral	0.186
OPA1	O60313-1.3	K74E	Neutral	0.025
OPA1	O60313-1.3	K74F	Neutral	0.179
OPA1	O60313-1.3	K74G	Neutral	0.218
OPA1	O60313-1.3	K74H	Neutral	0.1
OPA1	O60313-1.3	K74I	Neutral	0.171
OPA1	O60313-1.3	K74L	Neutral	0.072
OPA1	O60313-1.3	K74M	Neutral	0.04
OPA1	O60313-1.3	K74N	Neutral	0.064
OPA1	O60313-1.3	K74P	Neutral	0.055
OPA1	O60313-1.3	K74Q	Neutral	0.018
OPA1	O60313-1.3	K74R	Neutral	0.013
OPA1	O60313-1.3	K74S	Neutral	0.036
OPA1	O60313-1.3	K74T	Neutral	0.083
OPA1	O60313-1.3	K74V	Neutral	0.102
OPA1	O60313-1.3	K74W	Neutral	0.114
OPA1	O60313-1.3	K74Y	Neutral	0.136
OPA1	O60313-1.3	F75A	Neutral	0.018
OPA1	O60313-1.3	F75C	Neutral	0.035
OPA1	O60313-1.3	F75D	Neutral	0.021
OPA1	O60313-1.3	F75E	Neutral	0.026
OPA1	O60313-1.3	F75G	Neutral	0.036
OPA1	O60313-1.3	F75H	Neutral	0.007
OPA1	O60313-1.3	F75I	Neutral	0.01
OPA1	O60313-1.3	F75K	Neutral	0.021
OPA1	O60313-1.3	F75L	Neutral	0.01
OPA1	O60313-1.3	F75M	Neutral	0.006
OPA1	O60313-1.3	F75N	Neutral	0.025
OPA1	O60313-1.3	F75P	Neutral	0.197
OPA1	O60313-1.3	F75Q	Neutral	0.038
OPA1	O60313-1.3	F75R	Neutral	0.019
OPA1	O60313-1.3	F75S	Neutral	0.014
OPA1	O60313-1.3	F75T	Neutral	0.019
OPA1	O60313-1.3	F75V	Neutral	0.017
OPA1	O60313-1.3	F75W	Neutral	0.002
OPA1	O60313-1.3	F75Y	Neutral	0.0
OPA1	O60313-1.3	S76A	Neutral	0.001
OPA1	O60313-1.3	S76C	Neutral	0.006
OPA1	O60313-1.3	S76D	Neutral	0.003
OPA1	O60313-1.3	S76E	Neutral	0.003
OPA1	O60313-1.3	S76F	Neutral	0.007
OPA1	O60313-1.3	S76G	Neutral	0.005
OPA1	O60313-1.3	S76H	Neutral	0.012
OPA1	O60313-1.3	S76I	Neutral	0.008
OPA1	O60313-1.3	S76K	Neutral	0.002
OPA1	O60313-1.3	S76L	Neutral	0.008
OPA1	O60313-1.3	S76M	Neutral	0.004
OPA1	O60313-1.3	S76N	Neutral	0.001
OPA1	O60313-1.3	S76P	Neutral	0.008
OPA1	O60313-1.3	S76Q	Neutral	0.004
OPA1	O60313-1.3	S76R	Neutral	0.005
OPA1	O60313-1.3	S76T	Neutral	0.001
OPA1	O60313-1.3	S76V	Neutral	0.014
OPA1	O60313-1.3	S76W	Neutral	0.012
OPA1	O60313-1.3	S76Y	Neutral	0.015
OPA1	O60313-1.3	P77A	Neutral	0.042
OPA1	O60313-1.3	P77C	Neutral	0.311
OPA1	O60313-1.3	P77D	Neutral	0.017
OPA1	O60313-1.3	P77E	Neutral	0.018
OPA1	O60313-1.3	P77F	Neutral	0.349
OPA1	O60313-1.3	P77G	Neutral	0.082
OPA1	O60313-1.3	P77H	Neutral	0.096
OPA1	O60313-1.3	P77I	Neutral	0.16
OPA1	O60313-1.3	P77K	Neutral	0.012
OPA1	O60313-1.3	P77L	Neutral	0.173
OPA1	O60313-1.3	P77M	Neutral	0.1
OPA1	O60313-1.3	P77N	Neutral	0.055
OPA1	O60313-1.3	P77Q	Neutral	0.026
OPA1	O60313-1.3	P77R	Neutral	0.032
OPA1	O60313-1.3	P77S	Neutral	0.032
OPA1	O60313-1.3	P77T	Neutral	0.043
OPA1	O60313-1.3	P77V	Neutral	0.107
OPA1	O60313-1.3	P77W	Neutral	0.24
OPA1	O60313-1.3	P77Y	Neutral	0.278
OPA1	O60313-1.3	I78A	Neutral	0.0
OPA1	O60313-1.3	I78C	Neutral	0.001
OPA1	O60313-1.3	I78D	Neutral	0.001
OPA1	O60313-1.3	I78E	Neutral	0.002
OPA1	O60313-1.3	I78F	Neutral	0.001
OPA1	O60313-1.3	I78G	Neutral	0.007
OPA1	O60313-1.3	I78H	Neutral	0.003
OPA1	O60313-1.3	I78K	Neutral	0.001
OPA1	O60313-1.3	I78L	Neutral	0.0
OPA1	O60313-1.3	I78M	Neutral	0.0
OPA1	O60313-1.3	I78N	Neutral	0.002
OPA1	O60313-1.3	I78P	Neutral	0.005
OPA1	O60313-1.3	I78Q	Neutral	0.002
OPA1	O60313-1.3	I78R	Neutral	0.001
OPA1	O60313-1.3	I78S	Neutral	0.001
OPA1	O60313-1.3	I78T	Neutral	0.0
OPA1	O60313-1.3	I78V	Neutral	0.0
OPA1	O60313-1.3	I78W	Neutral	0.009
OPA1	O60313-1.3	I78Y	Neutral	0.001
OPA1	O60313-1.3	K79A	Neutral	0.037
OPA1	O60313-1.3	K79C	Neutral	0.158
OPA1	O60313-1.3	K79D	Neutral	0.101
OPA1	O60313-1.3	K79E	Neutral	0.013
OPA1	O60313-1.3	K79F	Neutral	0.097
OPA1	O60313-1.3	K79G	Neutral	0.121
OPA1	O60313-1.3	K79H	Neutral	0.052
OPA1	O60313-1.3	K79I	Neutral	0.092
OPA1	O60313-1.3	K79L	Neutral	0.037
OPA1	O60313-1.3	K79M	Neutral	0.02
OPA1	O60313-1.3	K79N	Neutral	0.033
OPA1	O60313-1.3	K79P	Neutral	0.028
OPA1	O60313-1.3	K79Q	Neutral	0.009
OPA1	O60313-1.3	K79R	Neutral	0.006
OPA1	O60313-1.3	K79S	Neutral	0.018
OPA1	O60313-1.3	K79T	Neutral	0.043
OPA1	O60313-1.3	K79V	Neutral	0.053
OPA1	O60313-1.3	K79W	Neutral	0.06
OPA1	O60313-1.3	K79Y	Neutral	0.072
OPA1	O60313-1.3	Y80A	Neutral	0.089
OPA1	O60313-1.3	Y80C	Neutral	0.157
OPA1	O60313-1.3	Y80D	Neutral	0.104
OPA1	O60313-1.3	Y80E	Neutral	0.046
OPA1	O60313-1.3	Y80F	Neutral	0.001
OPA1	O60313-1.3	Y80G	Neutral	0.166
OPA1	O60313-1.3	Y80H	Neutral	0.001
OPA1	O60313-1.3	Y80I	Neutral	0.034
OPA1	O60313-1.3	Y80K	Neutral	0.037
OPA1	O60313-1.3	Y80L	Neutral	0.037
OPA1	O60313-1.3	Y80M	Neutral	0.056
OPA1	O60313-1.3	Y80N	Neutral	0.045
OPA1	O60313-1.3	Y80P	Neutral	0.31
OPA1	O60313-1.3	Y80Q	Neutral	0.024
OPA1	O60313-1.3	Y80R	Neutral	0.036
OPA1	O60313-1.3	Y80S	Neutral	0.068
OPA1	O60313-1.3	Y80T	Neutral	0.093
OPA1	O60313-1.3	Y80V	Neutral	0.053
OPA1	O60313-1.3	Y80W	Neutral	0.001
OPA1	O60313-1.3	G81A	Neutral	0.049
OPA1	O60313-1.3	G81C	Neutral	0.385
OPA1	O60313-1.3	G81D	Neutral	0.082
OPA1	O60313-1.3	G81E	Neutral	0.214
OPA1	O60313-1.3	G81F	Neutral	0.2
OPA1	O60313-1.3	G81H	Neutral	0.295
OPA1	O60313-1.3	G81I	Neutral	0.426
OPA1	O60313-1.3	G81K	Neutral	0.152
OPA1	O60313-1.3	G81L	Neutral	0.449
OPA1	O60313-1.3	G81M	Neutral	0.302
OPA1	O60313-1.3	G81N	Neutral	0.034
OPA1	O60313-1.3	G81P	Neutral	0.213
OPA1	O60313-1.3	G81Q	Neutral	0.281
OPA1	O60313-1.3	G81R	Neutral	0.144
OPA1	O60313-1.3	G81S	Neutral	0.06
OPA1	O60313-1.3	G81T	Neutral	0.29
OPA1	O60313-1.3	G81V	Neutral	0.32
OPA1	O60313-1.3	G81W	Neutral	0.048
OPA1	O60313-1.3	G81Y	Neutral	0.342
OPA1	O60313-1.3	Y82A	Neutral	0.274
OPA1	O60313-1.3	Y82C	Neutral	0.419
OPA1	O60313-1.3	Y82D	Neutral	0.308
OPA1	O60313-1.3	Y82E	Neutral	0.157
OPA1	O60313-1.3	Y82F	Neutral	0.002
OPA1	O60313-1.3	Y82G	Neutral	0.435
OPA1	O60313-1.3	Y82H	Neutral	0.005
OPA1	O60313-1.3	Y82I	Neutral	0.119
OPA1	O60313-1.3	Y82K	Neutral	0.129
OPA1	O60313-1.3	Y82L	Neutral	0.129
OPA1	O60313-1.3	Y82M	Neutral	0.186
OPA1	O60313-1.3	Y82N	Neutral	0.155
OPA1	O60313-1.3	Y82P	Pathogenic	0.634
OPA1	O60313-1.3	Y82Q	Neutral	0.087
OPA1	O60313-1.3	Y82R	Neutral	0.127
OPA1	O60313-1.3	Y82S	Neutral	0.22
OPA1	O60313-1.3	Y82T	Neutral	0.284
OPA1	O60313-1.3	Y82V	Neutral	0.177
OPA1	O60313-1.3	Y82W	Neutral	0.004
OPA1	O60313-1.3	Q83A	Neutral	0.195
OPA1	O60313-1.3	Q83C	Pathogenic	0.542
OPA1	O60313-1.3	Q83D	Neutral	0.082
OPA1	O60313-1.3	Q83E	Neutral	0.013
OPA1	O60313-1.3	Q83F	Neutral	0.367
OPA1	O60313-1.3	Q83G	Neutral	0.465
OPA1	O60313-1.3	Q83H	Neutral	0.104
OPA1	O60313-1.3	Q83I	Neutral	0.374
OPA1	O60313-1.3	Q83K	Neutral	0.025
OPA1	O60313-1.3	Q83L	Neutral	0.184
OPA1	O60313-1.3	Q83M	Neutral	0.04
OPA1	O60313-1.3	Q83N	Neutral	0.097
OPA1	O60313-1.3	Q83P	Neutral	0.154
OPA1	O60313-1.3	Q83R	Neutral	0.023
OPA1	O60313-1.3	Q83S	Neutral	0.105
OPA1	O60313-1.3	Q83T	Neutral	0.219
OPA1	O60313-1.3	Q83V	Neutral	0.261
OPA1	O60313-1.3	Q83W	Neutral	0.106
OPA1	O60313-1.3	Q83Y	Neutral	0.126
OPA1	O60313-1.3	P84A	Neutral	0.083
OPA1	O60313-1.3	P84C	Neutral	0.484
OPA1	O60313-1.3	P84D	Neutral	0.036
OPA1	O60313-1.3	P84E	Neutral	0.037
OPA1	O60313-1.3	P84F	Pathogenic	0.528
OPA1	O60313-1.3	P84G	Neutral	0.156
OPA1	O60313-1.3	P84H	Neutral	0.181
OPA1	O60313-1.3	P84I	Neutral	0.284
OPA1	O60313-1.3	P84K	Neutral	0.025
OPA1	O60313-1.3	P84L	Neutral	0.303
OPA1	O60313-1.3	P84M	Neutral	0.187
OPA1	O60313-1.3	P84N	Neutral	0.109
OPA1	O60313-1.3	P84Q	Neutral	0.053
OPA1	O60313-1.3	P84R	Neutral	0.065
OPA1	O60313-1.3	P84S	Neutral	0.064
OPA1	O60313-1.3	P84T	Neutral	0.086
OPA1	O60313-1.3	P84V	Neutral	0.201
OPA1	O60313-1.3	P84W	Neutral	0.397
OPA1	O60313-1.3	P84Y	Neutral	0.446
OPA1	O60313-1.3	R85A	Neutral	0.002
OPA1	O60313-1.3	R85C	Neutral	0.007
OPA1	O60313-1.3	R85D	Neutral	0.013
OPA1	O60313-1.3	R85E	Neutral	0.001
OPA1	O60313-1.3	R85F	Neutral	0.004
OPA1	O60313-1.3	R85G	Neutral	0.005
OPA1	O60313-1.3	R85H	Neutral	0.001
OPA1	O60313-1.3	R85I	Neutral	0.004
OPA1	O60313-1.3	R85K	Neutral	0.0
OPA1	O60313-1.3	R85L	Neutral	0.002
OPA1	O60313-1.3	R85M	Neutral	0.001
OPA1	O60313-1.3	R85N	Neutral	0.001
OPA1	O60313-1.3	R85P	Neutral	0.003
OPA1	O60313-1.3	R85Q	Neutral	0.0
OPA1	O60313-1.3	R85S	Neutral	0.002
OPA1	O60313-1.3	R85T	Neutral	0.002
OPA1	O60313-1.3	R85V	Neutral	0.006
OPA1	O60313-1.3	R85W	Neutral	0.003
OPA1	O60313-1.3	R85Y	Neutral	0.003
OPA1	O60313-1.3	R86A	Pathogenic	0.831
OPA1	O60313-1.3	R86C	Pathogenic	0.96
OPA1	O60313-1.3	R86D	Pathogenic	0.977
OPA1	O60313-1.3	R86E	Pathogenic	0.826
OPA1	O60313-1.3	R86F	Pathogenic	0.932
OPA1	O60313-1.3	R86G	Pathogenic	0.946
OPA1	O60313-1.3	R86H	Pathogenic	0.708
OPA1	O60313-1.3	R86I	Pathogenic	0.929
OPA1	O60313-1.3	R86K	Neutral	0.461
OPA1	O60313-1.3	R86L	Pathogenic	0.832
OPA1	O60313-1.3	R86M	Pathogenic	0.724
OPA1	O60313-1.3	R86N	Pathogenic	0.813
OPA1	O60313-1.3	R86P	Pathogenic	0.915
OPA1	O60313-1.3	R86Q	Pathogenic	0.531
OPA1	O60313-1.3	R86S	Pathogenic	0.874
OPA1	O60313-1.3	R86T	Pathogenic	0.851
OPA1	O60313-1.3	R86V	Pathogenic	0.954
OPA1	O60313-1.3	R86W	Pathogenic	0.9
OPA1	O60313-1.3	R86Y	Pathogenic	0.912
OPA1	O60313-1.3	N87A	Neutral	0.197
OPA1	O60313-1.3	N87C	Neutral	0.292
OPA1	O60313-1.3	N87D	Neutral	0.021
OPA1	O60313-1.3	N87E	Neutral	0.065
OPA1	O60313-1.3	N87F	Neutral	0.15
OPA1	O60313-1.3	N87G	Neutral	0.035
OPA1	O60313-1.3	N87H	Neutral	0.012
OPA1	O60313-1.3	N87I	Neutral	0.154
OPA1	O60313-1.3	N87K	Neutral	0.043
OPA1	O60313-1.3	N87L	Neutral	0.167
OPA1	O60313-1.3	N87M	Neutral	0.096
OPA1	O60313-1.3	N87P	Neutral	0.155
OPA1	O60313-1.3	N87Q	Neutral	0.047
OPA1	O60313-1.3	N87R	Neutral	0.041
OPA1	O60313-1.3	N87S	Neutral	0.014
OPA1	O60313-1.3	N87T	Neutral	0.033
OPA1	O60313-1.3	N87V	Neutral	0.251
OPA1	O60313-1.3	N87W	Neutral	0.232
OPA1	O60313-1.3	N87Y	Neutral	0.113
OPA1	O60313-1.3	F88A	Pathogenic	0.632
OPA1	O60313-1.3	F88C	Pathogenic	0.774
OPA1	O60313-1.3	F88D	Pathogenic	0.67
OPA1	O60313-1.3	F88E	Pathogenic	0.71
OPA1	O60313-1.3	F88G	Pathogenic	0.778
OPA1	O60313-1.3	F88H	Neutral	0.379
OPA1	O60313-1.3	F88I	Neutral	0.492
OPA1	O60313-1.3	F88K	Pathogenic	0.662
OPA1	O60313-1.3	F88L	Neutral	0.475
OPA1	O60313-1.3	F88M	Neutral	0.37
OPA1	O60313-1.3	F88N	Pathogenic	0.707
OPA1	O60313-1.3	F88P	Pathogenic	0.958
OPA1	O60313-1.3	F88Q	Pathogenic	0.785
OPA1	O60313-1.3	F88R	Pathogenic	0.648
OPA1	O60313-1.3	F88S	Pathogenic	0.561
OPA1	O60313-1.3	F88T	Pathogenic	0.643
OPA1	O60313-1.3	F88V	Pathogenic	0.611
OPA1	O60313-1.3	F88W	Neutral	0.172
OPA1	O60313-1.3	F88Y	Neutral	0.019
OPA1	O60313-1.3	W89A	Pathogenic	0.541
OPA1	O60313-1.3	W89C	Neutral	0.447
OPA1	O60313-1.3	W89D	Pathogenic	0.582
OPA1	O60313-1.3	W89E	Neutral	0.367
OPA1	O60313-1.3	W89F	Neutral	0.077
OPA1	O60313-1.3	W89G	Neutral	0.222
OPA1	O60313-1.3	W89H	Neutral	0.295
OPA1	O60313-1.3	W89I	Pathogenic	0.851
OPA1	O60313-1.3	W89K	Neutral	0.316
OPA1	O60313-1.3	W89L	Pathogenic	0.643
OPA1	O60313-1.3	W89M	Neutral	0.288
OPA1	O60313-1.3	W89N	Pathogenic	0.623
OPA1	O60313-1.3	W89P	Pathogenic	0.844
OPA1	O60313-1.3	W89Q	Neutral	0.23
OPA1	O60313-1.3	W89R	Neutral	0.324
OPA1	O60313-1.3	W89S	Neutral	0.468
OPA1	O60313-1.3	W89T	Neutral	0.299
OPA1	O60313-1.3	W89V	Pathogenic	0.757
OPA1	O60313-1.3	W89Y	Neutral	0.014
OPA1	O60313-1.3	P90A	Neutral	0.031
OPA1	O60313-1.3	P90C	Neutral	0.249
OPA1	O60313-1.3	P90D	Neutral	0.013
OPA1	O60313-1.3	P90E	Neutral	0.014
OPA1	O60313-1.3	P90F	Neutral	0.283
OPA1	O60313-1.3	P90G	Neutral	0.062
OPA1	O60313-1.3	P90H	Neutral	0.072
OPA1	O60313-1.3	P90I	Neutral	0.123
OPA1	O60313-1.3	P90K	Neutral	0.009
OPA1	O60313-1.3	P90L	Neutral	0.133
OPA1	O60313-1.3	P90M	Neutral	0.075
OPA1	O60313-1.3	P90N	Neutral	0.041
OPA1	O60313-1.3	P90Q	Neutral	0.019
OPA1	O60313-1.3	P90R	Neutral	0.024
OPA1	O60313-1.3	P90S	Neutral	0.023
OPA1	O60313-1.3	P90T	Neutral	0.032
OPA1	O60313-1.3	P90V	Neutral	0.081
OPA1	O60313-1.3	P90W	Neutral	0.189
OPA1	O60313-1.3	P90Y	Neutral	0.221
OPA1	O60313-1.3	A91C	Neutral	0.261
OPA1	O60313-1.3	A91D	Pathogenic	0.669
OPA1	O60313-1.3	A91E	Neutral	0.423
OPA1	O60313-1.3	A91F	Pathogenic	0.542
OPA1	O60313-1.3	A91G	Neutral	0.331
OPA1	O60313-1.3	A91H	Pathogenic	0.806
OPA1	O60313-1.3	A91I	Neutral	0.296
OPA1	O60313-1.3	A91K	Neutral	0.326
OPA1	O60313-1.3	A91L	Neutral	0.316
OPA1	O60313-1.3	A91M	Neutral	0.415
OPA1	O60313-1.3	A91N	Pathogenic	0.698
OPA1	O60313-1.3	A91P	Pathogenic	0.563
OPA1	O60313-1.3	A91Q	Pathogenic	0.514
OPA1	O60313-1.3	A91R	Neutral	0.312
OPA1	O60313-1.3	A91S	Neutral	0.148
OPA1	O60313-1.3	A91T	Neutral	0.379
OPA1	O60313-1.3	A91V	Neutral	0.21
OPA1	O60313-1.3	A91W	Pathogenic	0.669
OPA1	O60313-1.3	A91Y	Pathogenic	0.712
OPA1	O60313-1.3	R92A	Pathogenic	0.826
OPA1	O60313-1.3	R92C	Pathogenic	0.958
OPA1	O60313-1.3	R92D	Pathogenic	0.976
OPA1	O60313-1.3	R92E	Pathogenic	0.82
OPA1	O60313-1.3	R92F	Pathogenic	0.93
OPA1	O60313-1.3	R92G	Pathogenic	0.944
OPA1	O60313-1.3	R92H	Pathogenic	0.699
OPA1	O60313-1.3	R92I	Pathogenic	0.926
OPA1	O60313-1.3	R92K	Neutral	0.451
OPA1	O60313-1.3	R92L	Pathogenic	0.826
OPA1	O60313-1.3	R92M	Pathogenic	0.716
OPA1	O60313-1.3	R92N	Pathogenic	0.807
OPA1	O60313-1.3	R92P	Pathogenic	0.911
OPA1	O60313-1.3	R92Q	Pathogenic	0.521
OPA1	O60313-1.3	R92S	Pathogenic	0.869
OPA1	O60313-1.3	R92T	Pathogenic	0.845
OPA1	O60313-1.3	R92V	Pathogenic	0.952
OPA1	O60313-1.3	R92W	Pathogenic	0.896
OPA1	O60313-1.3	R92Y	Pathogenic	0.909
OPA1	O60313-1.3	L93A	Neutral	0.188
OPA1	O60313-1.3	L93C	Neutral	0.315
OPA1	O60313-1.3	L93D	Pathogenic	0.697
OPA1	O60313-1.3	L93E	Neutral	0.489
OPA1	O60313-1.3	L93F	Neutral	0.238
OPA1	O60313-1.3	L93G	Pathogenic	0.798
OPA1	O60313-1.3	L93H	Pathogenic	0.667
OPA1	O60313-1.3	L93I	Neutral	0.037
OPA1	O60313-1.3	L93K	Neutral	0.195
OPA1	O60313-1.3	L93M	Neutral	0.027
OPA1	O60313-1.3	L93N	Neutral	0.485
OPA1	O60313-1.3	L93P	Pathogenic	0.755
OPA1	O60313-1.3	L93Q	Neutral	0.33
OPA1	O60313-1.3	L93R	Neutral	0.186
OPA1	O60313-1.3	L93S	Neutral	0.333
OPA1	O60313-1.3	L93T	Neutral	0.195
OPA1	O60313-1.3	L93V	Neutral	0.068
OPA1	O60313-1.3	L93W	Pathogenic	0.608
OPA1	O60313-1.3	L93Y	Neutral	0.328
OPA1	O60313-1.3	A94C	Neutral	0.416
OPA1	O60313-1.3	A94D	Pathogenic	0.803
OPA1	O60313-1.3	A94E	Pathogenic	0.597
OPA1	O60313-1.3	A94F	Pathogenic	0.705
OPA1	O60313-1.3	A94G	Neutral	0.499
OPA1	O60313-1.3	A94H	Pathogenic	0.893
OPA1	O60313-1.3	A94I	Neutral	0.458
OPA1	O60313-1.3	A94K	Neutral	0.493
OPA1	O60313-1.3	A94L	Neutral	0.482
OPA1	O60313-1.3	A94M	Pathogenic	0.588
OPA1	O60313-1.3	A94N	Pathogenic	0.823
OPA1	O60313-1.3	A94P	Pathogenic	0.722
OPA1	O60313-1.3	A94Q	Pathogenic	0.68
OPA1	O60313-1.3	A94R	Neutral	0.478
OPA1	O60313-1.3	A94S	Neutral	0.259
OPA1	O60313-1.3	A94T	Pathogenic	0.551
OPA1	O60313-1.3	A94V	Neutral	0.349
OPA1	O60313-1.3	A94W	Pathogenic	0.803
OPA1	O60313-1.3	A94Y	Pathogenic	0.833
OPA1	O60313-1.3	T95A	Neutral	0.008
OPA1	O60313-1.3	T95C	Neutral	0.014
OPA1	O60313-1.3	T95D	Neutral	0.01
OPA1	O60313-1.3	T95E	Neutral	0.011
OPA1	O60313-1.3	T95F	Neutral	0.016
OPA1	O60313-1.3	T95G	Neutral	0.05
OPA1	O60313-1.3	T95H	Neutral	0.061
OPA1	O60313-1.3	T95I	Neutral	0.006
OPA1	O60313-1.3	T95K	Neutral	0.007
OPA1	O60313-1.3	T95L	Neutral	0.006
OPA1	O60313-1.3	T95M	Neutral	0.01
OPA1	O60313-1.3	T95N	Neutral	0.004
OPA1	O60313-1.3	T95P	Neutral	0.017
OPA1	O60313-1.3	T95Q	Neutral	0.016
OPA1	O60313-1.3	T95R	Neutral	0.007
OPA1	O60313-1.3	T95S	Neutral	0.002
OPA1	O60313-1.3	T95V	Neutral	0.004
OPA1	O60313-1.3	T95W	Neutral	0.01
OPA1	O60313-1.3	T95Y	Neutral	0.034
OPA1	O60313-1.3	R96A	Pathogenic	0.572
OPA1	O60313-1.3	R96C	Pathogenic	0.867
OPA1	O60313-1.3	R96D	Pathogenic	0.919
OPA1	O60313-1.3	R96E	Pathogenic	0.562
OPA1	O60313-1.3	R96F	Pathogenic	0.789
OPA1	O60313-1.3	R96G	Pathogenic	0.827
OPA1	O60313-1.3	R96H	Neutral	0.396
OPA1	O60313-1.3	R96I	Pathogenic	0.78
OPA1	O60313-1.3	R96K	Neutral	0.189
OPA1	O60313-1.3	R96L	Pathogenic	0.573
OPA1	O60313-1.3	R96M	Neutral	0.416
OPA1	O60313-1.3	R96N	Pathogenic	0.542
OPA1	O60313-1.3	R96P	Pathogenic	0.744
OPA1	O60313-1.3	R96Q	Neutral	0.235
OPA1	O60313-1.3	R96S	Pathogenic	0.652
OPA1	O60313-1.3	R96T	Pathogenic	0.607
OPA1	O60313-1.3	R96V	Pathogenic	0.849
OPA1	O60313-1.3	R96W	Pathogenic	0.709
OPA1	O60313-1.3	R96Y	Pathogenic	0.738
OPA1	O60313-1.3	L97A	Neutral	0.06
OPA1	O60313-1.3	L97C	Neutral	0.114
OPA1	O60313-1.3	L97D	Neutral	0.39
OPA1	O60313-1.3	L97E	Neutral	0.21
OPA1	O60313-1.3	L97F	Neutral	0.08
OPA1	O60313-1.3	L97G	Pathogenic	0.524
OPA1	O60313-1.3	L97H	Neutral	0.358
OPA1	O60313-1.3	L97I	Neutral	0.011
OPA1	O60313-1.3	L97K	Neutral	0.063
OPA1	O60313-1.3	L97M	Neutral	0.008
OPA1	O60313-1.3	L97N	Neutral	0.208
OPA1	O60313-1.3	L97P	Neutral	0.462
OPA1	O60313-1.3	L97Q	Neutral	0.121
OPA1	O60313-1.3	L97R	Neutral	0.06
OPA1	O60313-1.3	L97S	Neutral	0.122
OPA1	O60313-1.3	L97T	Neutral	0.063
OPA1	O60313-1.3	L97V	Neutral	0.02
OPA1	O60313-1.3	L97W	Neutral	0.302
OPA1	O60313-1.3	L97Y	Neutral	0.12
OPA1	O60313-1.3	L98A	Pathogenic	0.616
OPA1	O60313-1.3	L98C	Pathogenic	0.761
OPA1	O60313-1.3	L98D	Pathogenic	0.941
OPA1	O60313-1.3	L98E	Pathogenic	0.869
OPA1	O60313-1.3	L98F	Pathogenic	0.684
OPA1	O60313-1.3	L98G	Pathogenic	0.965
OPA1	O60313-1.3	L98H	Pathogenic	0.933
OPA1	O60313-1.3	L98I	Neutral	0.21
OPA1	O60313-1.3	L98K	Pathogenic	0.627
OPA1	O60313-1.3	L98M	Neutral	0.159
OPA1	O60313-1.3	L98N	Pathogenic	0.867
OPA1	O60313-1.3	L98P	Pathogenic	0.955
OPA1	O60313-1.3	L98Q	Pathogenic	0.774
OPA1	O60313-1.3	L98R	Pathogenic	0.613
OPA1	O60313-1.3	L98S	Pathogenic	0.776
OPA1	O60313-1.3	L98T	Pathogenic	0.628
OPA1	O60313-1.3	L98V	Neutral	0.336
OPA1	O60313-1.3	L98W	Pathogenic	0.915
OPA1	O60313-1.3	L98Y	Pathogenic	0.772
OPA1	O60313-1.3	K99A	Neutral	0.223
OPA1	O60313-1.3	K99C	Pathogenic	0.583
OPA1	O60313-1.3	K99D	Neutral	0.458
OPA1	O60313-1.3	K99E	Neutral	0.087
OPA1	O60313-1.3	K99F	Neutral	0.446
OPA1	O60313-1.3	K99G	Pathogenic	0.507
OPA1	O60313-1.3	K99H	Neutral	0.29
OPA1	O60313-1.3	K99I	Neutral	0.432
OPA1	O60313-1.3	K99L	Neutral	0.224
OPA1	O60313-1.3	K99M	Neutral	0.133
OPA1	O60313-1.3	K99N	Neutral	0.203
OPA1	O60313-1.3	K99P	Neutral	0.177
OPA1	O60313-1.3	K99Q	Neutral	0.062
OPA1	O60313-1.3	K99R	Neutral	0.045
OPA1	O60313-1.3	K99S	Neutral	0.122
OPA1	O60313-1.3	K99T	Neutral	0.249
OPA1	O60313-1.3	K99V	Neutral	0.295
OPA1	O60313-1.3	K99W	Neutral	0.322
OPA1	O60313-1.3	K99Y	Neutral	0.367
OPA1	O60313-1.3	L100A	Neutral	0.029
OPA1	O60313-1.3	L100C	Neutral	0.056
OPA1	O60313-1.3	L100D	Neutral	0.23
OPA1	O60313-1.3	L100E	Neutral	0.111
OPA1	O60313-1.3	L100F	Neutral	0.039
OPA1	O60313-1.3	L100G	Neutral	0.34
OPA1	O60313-1.3	L100H	Neutral	0.206
OPA1	O60313-1.3	L100I	Neutral	0.005
OPA1	O60313-1.3	L100K	Neutral	0.031
OPA1	O60313-1.3	L100M	Neutral	0.004
OPA1	O60313-1.3	L100N	Neutral	0.109
OPA1	O60313-1.3	L100P	Neutral	0.286
OPA1	O60313-1.3	L100Q	Neutral	0.06
OPA1	O60313-1.3	L100R	Neutral	0.029
OPA1	O60313-1.3	L100S	Neutral	0.061
OPA1	O60313-1.3	L100T	Neutral	0.031
OPA1	O60313-1.3	L100V	Neutral	0.009
OPA1	O60313-1.3	L100W	Neutral	0.168
OPA1	O60313-1.3	L100Y	Neutral	0.06
OPA1	O60313-1.3	R101A	Pathogenic	0.782
OPA1	O60313-1.3	R101C	Pathogenic	0.946
OPA1	O60313-1.3	R101D	Pathogenic	0.968
OPA1	O60313-1.3	R101E	Pathogenic	0.775
OPA1	O60313-1.3	R101F	Pathogenic	0.909
OPA1	O60313-1.3	R101G	Pathogenic	0.928
OPA1	O60313-1.3	R101H	Pathogenic	0.637
OPA1	O60313-1.3	R101I	Pathogenic	0.905
OPA1	O60313-1.3	R101K	Neutral	0.384
OPA1	O60313-1.3	R101L	Pathogenic	0.782
OPA1	O60313-1.3	R101M	Pathogenic	0.656
OPA1	O60313-1.3	R101N	Pathogenic	0.76
OPA1	O60313-1.3	R101P	Pathogenic	0.886
OPA1	O60313-1.3	R101Q	Neutral	0.452
OPA1	O60313-1.3	R101S	Pathogenic	0.834
OPA1	O60313-1.3	R101T	Pathogenic	0.806
OPA1	O60313-1.3	R101V	Pathogenic	0.938
OPA1	O60313-1.3	R101W	Pathogenic	0.867
OPA1	O60313-1.3	R101Y	Pathogenic	0.883
OPA1	O60313-1.3	Y102A	Pathogenic	0.926
OPA1	O60313-1.3	Y102C	Pathogenic	0.96
OPA1	O60313-1.3	Y102D	Pathogenic	0.937
OPA1	O60313-1.3	Y102E	Pathogenic	0.86
OPA1	O60313-1.3	Y102F	Neutral	0.063
OPA1	O60313-1.3	Y102G	Pathogenic	0.962
OPA1	O60313-1.3	Y102H	Neutral	0.154
OPA1	O60313-1.3	Y102I	Pathogenic	0.818
OPA1	O60313-1.3	Y102K	Pathogenic	0.831
OPA1	O60313-1.3	Y102L	Pathogenic	0.831
OPA1	O60313-1.3	Y102M	Pathogenic	0.883
OPA1	O60313-1.3	Y102N	Pathogenic	0.859
OPA1	O60313-1.3	Y102P	Pathogenic	0.983
OPA1	O60313-1.3	Y102Q	Pathogenic	0.761
OPA1	O60313-1.3	Y102R	Pathogenic	0.829
OPA1	O60313-1.3	Y102S	Pathogenic	0.903
OPA1	O60313-1.3	Y102T	Pathogenic	0.929
OPA1	O60313-1.3	Y102V	Pathogenic	0.877
OPA1	O60313-1.3	Y102W	Neutral	0.107
OPA1	O60313-1.3	L103A	Neutral	0.084
OPA1	O60313-1.3	L103C	Neutral	0.154
OPA1	O60313-1.3	L103D	Neutral	0.476
OPA1	O60313-1.3	L103E	Neutral	0.275
OPA1	O60313-1.3	L103F	Neutral	0.11
OPA1	O60313-1.3	L103G	Pathogenic	0.611
OPA1	O60313-1.3	L103H	Neutral	0.442
OPA1	O60313-1.3	L103I	Neutral	0.015
OPA1	O60313-1.3	L103K	Neutral	0.088
OPA1	O60313-1.3	L103M	Neutral	0.011
OPA1	O60313-1.3	L103N	Neutral	0.272
OPA1	O60313-1.3	L103P	Pathogenic	0.55
OPA1	O60313-1.3	L103Q	Neutral	0.163
OPA1	O60313-1.3	L103R	Neutral	0.083
OPA1	O60313-1.3	L103S	Neutral	0.165
OPA1	O60313-1.3	L103T	Neutral	0.088
OPA1	O60313-1.3	L103V	Neutral	0.028
OPA1	O60313-1.3	L103W	Neutral	0.381
OPA1	O60313-1.3	L103Y	Neutral	0.162
OPA1	O60313-1.3	I104A	Neutral	0.006
OPA1	O60313-1.3	I104C	Neutral	0.012
OPA1	O60313-1.3	I104D	Neutral	0.02
OPA1	O60313-1.3	I104E	Neutral	0.025
OPA1	O60313-1.3	I104F	Neutral	0.01
OPA1	O60313-1.3	I104G	Neutral	0.095
OPA1	O60313-1.3	I104H	Neutral	0.05
OPA1	O60313-1.3	I104K	Neutral	0.018
OPA1	O60313-1.3	I104L	Neutral	0.001
OPA1	O60313-1.3	I104M	Neutral	0.002
OPA1	O60313-1.3	I104N	Neutral	0.024
OPA1	O60313-1.3	I104P	Neutral	0.075
OPA1	O60313-1.3	I104Q	Neutral	0.036
OPA1	O60313-1.3	I104R	Neutral	0.017
OPA1	O60313-1.3	I104S	Neutral	0.013
OPA1	O60313-1.3	I104T	Neutral	0.006
OPA1	O60313-1.3	I104V	Neutral	0.0
OPA1	O60313-1.3	I104W	Neutral	0.125
OPA1	O60313-1.3	I104Y	Neutral	0.013
OPA1	O60313-1.3	L105A	Pathogenic	0.736
OPA1	O60313-1.3	L105C	Pathogenic	0.848
OPA1	O60313-1.3	L105D	Pathogenic	0.965
OPA1	O60313-1.3	L105E	Pathogenic	0.92
OPA1	O60313-1.3	L105F	Pathogenic	0.791
OPA1	O60313-1.3	L105G	Pathogenic	0.98
OPA1	O60313-1.3	L105H	Pathogenic	0.96
OPA1	O60313-1.3	L105I	Neutral	0.316
OPA1	O60313-1.3	L105K	Pathogenic	0.746
OPA1	O60313-1.3	L105M	Neutral	0.248
OPA1	O60313-1.3	L105N	Pathogenic	0.919
OPA1	O60313-1.3	L105P	Pathogenic	0.974
OPA1	O60313-1.3	L105Q	Pathogenic	0.856
OPA1	O60313-1.3	L105R	Pathogenic	0.734
OPA1	O60313-1.3	L105S	Pathogenic	0.858
OPA1	O60313-1.3	L105T	Pathogenic	0.746
OPA1	O60313-1.3	L105V	Neutral	0.468
OPA1	O60313-1.3	L105W	Pathogenic	0.949
OPA1	O60313-1.3	L105Y	Pathogenic	0.855
OPA1	O60313-1.3	G106A	Pathogenic	0.679
OPA1	O60313-1.3	G106C	Pathogenic	0.963
OPA1	O60313-1.3	G106D	Pathogenic	0.786
OPA1	O60313-1.3	G106E	Pathogenic	0.918
OPA1	O60313-1.3	G106F	Pathogenic	0.911
OPA1	O60313-1.3	G106H	Pathogenic	0.945
OPA1	O60313-1.3	G106I	Pathogenic	0.968
OPA1	O60313-1.3	G106K	Pathogenic	0.881
OPA1	O60313-1.3	G106L	Pathogenic	0.971
OPA1	O60313-1.3	G106M	Pathogenic	0.947
OPA1	O60313-1.3	G106N	Pathogenic	0.592
OPA1	O60313-1.3	G106P	Pathogenic	0.918
OPA1	O60313-1.3	G106Q	Pathogenic	0.942
OPA1	O60313-1.3	G106R	Pathogenic	0.874
OPA1	O60313-1.3	G106S	Pathogenic	0.726
OPA1	O60313-1.3	G106T	Pathogenic	0.944
OPA1	O60313-1.3	G106V	Pathogenic	0.951
OPA1	O60313-1.3	G106W	Pathogenic	0.677
OPA1	O60313-1.3	G106Y	Pathogenic	0.956
OPA1	O60313-1.3	S107A	Neutral	0.03
OPA1	O60313-1.3	S107C	Neutral	0.12
OPA1	O60313-1.3	S107D	Neutral	0.056
OPA1	O60313-1.3	S107E	Neutral	0.059
OPA1	O60313-1.3	S107F	Neutral	0.136
OPA1	O60313-1.3	S107G	Neutral	0.099
OPA1	O60313-1.3	S107H	Neutral	0.208
OPA1	O60313-1.3	S107I	Neutral	0.139
OPA1	O60313-1.3	S107K	Neutral	0.04
OPA1	O60313-1.3	S107L	Neutral	0.151
OPA1	O60313-1.3	S107M	Neutral	0.086
OPA1	O60313-1.3	S107N	Neutral	0.023
OPA1	O60313-1.3	S107P	Neutral	0.146
OPA1	O60313-1.3	S107Q	Neutral	0.083
OPA1	O60313-1.3	S107R	Neutral	0.102
OPA1	O60313-1.3	S107T	Neutral	0.03
OPA1	O60313-1.3	S107V	Neutral	0.229
OPA1	O60313-1.3	S107W	Neutral	0.212
OPA1	O60313-1.3	S107Y	Neutral	0.247
OPA1	O60313-1.3	A108C	Pathogenic	0.576
OPA1	O60313-1.3	A108D	Pathogenic	0.886
OPA1	O60313-1.3	A108E	Pathogenic	0.738
OPA1	O60313-1.3	A108F	Pathogenic	0.819
OPA1	O60313-1.3	A108G	Pathogenic	0.655
OPA1	O60313-1.3	A108H	Pathogenic	0.941
OPA1	O60313-1.3	A108I	Pathogenic	0.617
OPA1	O60313-1.3	A108K	Pathogenic	0.649
OPA1	O60313-1.3	A108L	Pathogenic	0.639
OPA1	O60313-1.3	A108M	Pathogenic	0.731
OPA1	O60313-1.3	A108N	Pathogenic	0.899
OPA1	O60313-1.3	A108P	Pathogenic	0.831
OPA1	O60313-1.3	A108Q	Pathogenic	0.802
OPA1	O60313-1.3	A108R	Pathogenic	0.635
OPA1	O60313-1.3	A108S	Neutral	0.399
OPA1	O60313-1.3	A108T	Pathogenic	0.7
OPA1	O60313-1.3	A108V	Pathogenic	0.505
OPA1	O60313-1.3	A108W	Pathogenic	0.886
OPA1	O60313-1.3	A108Y	Pathogenic	0.905
OPA1	O60313-1.3	V109A	Neutral	0.319
OPA1	O60313-1.3	V109C	Pathogenic	0.73
OPA1	O60313-1.3	V109D	Pathogenic	0.823
OPA1	O60313-1.3	V109E	Pathogenic	0.653
OPA1	O60313-1.3	V109F	Pathogenic	0.656
OPA1	O60313-1.3	V109G	Pathogenic	0.889
OPA1	O60313-1.3	V109H	Pathogenic	0.914
OPA1	O60313-1.3	V109I	Neutral	0.027
OPA1	O60313-1.3	V109K	Pathogenic	0.553
OPA1	O60313-1.3	V109L	Neutral	0.204
OPA1	O60313-1.3	V109M	Neutral	0.283
OPA1	O60313-1.3	V109N	Pathogenic	0.847
OPA1	O60313-1.3	V109P	Pathogenic	0.862
OPA1	O60313-1.3	V109Q	Pathogenic	0.731
OPA1	O60313-1.3	V109R	Pathogenic	0.772
OPA1	O60313-1.3	V109S	Pathogenic	0.746
OPA1	O60313-1.3	V109T	Neutral	0.33
OPA1	O60313-1.3	V109W	Pathogenic	0.904
OPA1	O60313-1.3	V109Y	Pathogenic	0.714
OPA1	O60313-1.3	G110A	Pathogenic	0.528
OPA1	O60313-1.3	G110C	Pathogenic	0.932
OPA1	O60313-1.3	G110D	Pathogenic	0.661
OPA1	O60313-1.3	G110E	Pathogenic	0.856
OPA1	O60313-1.3	G110F	Pathogenic	0.845
OPA1	O60313-1.3	G110H	Pathogenic	0.901
OPA1	O60313-1.3	G110I	Pathogenic	0.942
OPA1	O60313-1.3	G110K	Pathogenic	0.797
OPA1	O60313-1.3	G110L	Pathogenic	0.947
OPA1	O60313-1.3	G110M	Pathogenic	0.905
OPA1	O60313-1.3	G110N	Neutral	0.435
OPA1	O60313-1.3	G110P	Pathogenic	0.856
OPA1	O60313-1.3	G110Q	Pathogenic	0.895
OPA1	O60313-1.3	G110R	Pathogenic	0.786
OPA1	O60313-1.3	G110S	Pathogenic	0.584
OPA1	O60313-1.3	G110T	Pathogenic	0.9
OPA1	O60313-1.3	G110V	Pathogenic	0.912
OPA1	O60313-1.3	G110W	Pathogenic	0.526
OPA1	O60313-1.3	G110Y	Pathogenic	0.919
OPA1	O60313-1.3	G111A	Neutral	0.463
OPA1	O60313-1.3	G111C	Pathogenic	0.913
OPA1	O60313-1.3	G111D	Pathogenic	0.6
OPA1	O60313-1.3	G111E	Pathogenic	0.821
OPA1	O60313-1.3	G111F	Pathogenic	0.808
OPA1	O60313-1.3	G111H	Pathogenic	0.876
OPA1	O60313-1.3	G111I	Pathogenic	0.926
OPA1	O60313-1.3	G111K	Pathogenic	0.751
OPA1	O60313-1.3	G111L	Pathogenic	0.932
OPA1	O60313-1.3	G111M	Pathogenic	0.879
OPA1	O60313-1.3	G111N	Neutral	0.372
OPA1	O60313-1.3	G111P	Pathogenic	0.82
OPA1	O60313-1.3	G111Q	Pathogenic	0.868
OPA1	O60313-1.3	G111R	Pathogenic	0.739
OPA1	O60313-1.3	G111S	Pathogenic	0.519
OPA1	O60313-1.3	G111T	Pathogenic	0.873
OPA1	O60313-1.3	G111V	Pathogenic	0.888
OPA1	O60313-1.3	G111W	Neutral	0.461
OPA1	O60313-1.3	G111Y	Pathogenic	0.898
OPA1	O60313-1.3	G112A	Pathogenic	0.593
OPA1	O60313-1.3	G112C	Pathogenic	0.947
OPA1	O60313-1.3	G112D	Pathogenic	0.716
OPA1	O60313-1.3	G112E	Pathogenic	0.885
OPA1	O60313-1.3	G112F	Pathogenic	0.876
OPA1	O60313-1.3	G112H	Pathogenic	0.922
OPA1	O60313-1.3	G112I	Pathogenic	0.955
OPA1	O60313-1.3	G112K	Pathogenic	0.836
OPA1	O60313-1.3	G112L	Pathogenic	0.959
OPA1	O60313-1.3	G112M	Pathogenic	0.925
OPA1	O60313-1.3	G112N	Neutral	0.499
OPA1	O60313-1.3	G112P	Pathogenic	0.885
OPA1	O60313-1.3	G112Q	Pathogenic	0.917
OPA1	O60313-1.3	G112R	Pathogenic	0.827
OPA1	O60313-1.3	G112S	Pathogenic	0.646
OPA1	O60313-1.3	G112T	Pathogenic	0.921
OPA1	O60313-1.3	G112V	Pathogenic	0.93
OPA1	O60313-1.3	G112W	Pathogenic	0.591
OPA1	O60313-1.3	G112Y	Pathogenic	0.937
OPA1	O60313-1.3	Y113A	Neutral	0.264
OPA1	O60313-1.3	Y113C	Neutral	0.407
OPA1	O60313-1.3	Y113D	Neutral	0.298
OPA1	O60313-1.3	Y113E	Neutral	0.15
OPA1	O60313-1.3	Y113F	Neutral	0.002
OPA1	O60313-1.3	Y113G	Neutral	0.423
OPA1	O60313-1.3	Y113H	Neutral	0.005
OPA1	O60313-1.3	Y113I	Neutral	0.114
OPA1	O60313-1.3	Y113K	Neutral	0.124
OPA1	O60313-1.3	Y113L	Neutral	0.124
OPA1	O60313-1.3	Y113M	Neutral	0.178
OPA1	O60313-1.3	Y113N	Neutral	0.148
OPA1	O60313-1.3	Y113P	Pathogenic	0.623
OPA1	O60313-1.3	Y113Q	Neutral	0.083
OPA1	O60313-1.3	Y113R	Neutral	0.122
OPA1	O60313-1.3	Y113S	Neutral	0.211
OPA1	O60313-1.3	Y113T	Neutral	0.274
OPA1	O60313-1.3	Y113V	Neutral	0.17
OPA1	O60313-1.3	Y113W	Neutral	0.003
OPA1	O60313-1.3	T114A	Pathogenic	0.785
OPA1	O60313-1.3	T114C	Pathogenic	0.86
OPA1	O60313-1.3	T114D	Pathogenic	0.826
OPA1	O60313-1.3	T114E	Pathogenic	0.835
OPA1	O60313-1.3	T114F	Pathogenic	0.882
OPA1	O60313-1.3	T114G	Pathogenic	0.959
OPA1	O60313-1.3	T114H	Pathogenic	0.966
OPA1	O60313-1.3	T114I	Pathogenic	0.725
OPA1	O60313-1.3	T114K	Pathogenic	0.769
OPA1	O60313-1.3	T114L	Pathogenic	0.743
OPA1	O60313-1.3	T114M	Pathogenic	0.817
OPA1	O60313-1.3	T114N	Pathogenic	0.655
OPA1	O60313-1.3	T114P	Pathogenic	0.888
OPA1	O60313-1.3	T114Q	Pathogenic	0.879
OPA1	O60313-1.3	T114R	Pathogenic	0.758
OPA1	O60313-1.3	T114S	Pathogenic	0.507
OPA1	O60313-1.3	T114V	Pathogenic	0.626
OPA1	O60313-1.3	T114W	Pathogenic	0.814
OPA1	O60313-1.3	T114Y	Pathogenic	0.94
OPA1	O60313-1.3	A115C	Neutral	0.306
OPA1	O60313-1.3	A115D	Pathogenic	0.716
OPA1	O60313-1.3	A115E	Neutral	0.478
OPA1	O60313-1.3	A115F	Pathogenic	0.596
OPA1	O60313-1.3	A115G	Neutral	0.382
OPA1	O60313-1.3	A115H	Pathogenic	0.839
OPA1	O60313-1.3	A115I	Neutral	0.344
OPA1	O60313-1.3	A115K	Neutral	0.376
OPA1	O60313-1.3	A115L	Neutral	0.365
OPA1	O60313-1.3	A115M	Neutral	0.469
OPA1	O60313-1.3	A115N	Pathogenic	0.742
OPA1	O60313-1.3	A115P	Pathogenic	0.616
OPA1	O60313-1.3	A115Q	Pathogenic	0.569
OPA1	O60313-1.3	A115R	Neutral	0.361
OPA1	O60313-1.3	A115S	Neutral	0.178
OPA1	O60313-1.3	A115T	Neutral	0.432
OPA1	O60313-1.3	A115V	Neutral	0.249
OPA1	O60313-1.3	A115W	Pathogenic	0.716
OPA1	O60313-1.3	A115Y	Pathogenic	0.755
OPA1	O60313-1.3	K116A	Neutral	0.31
OPA1	O60313-1.3	K116C	Pathogenic	0.686
OPA1	O60313-1.3	K116D	Pathogenic	0.568
OPA1	O60313-1.3	K116E	Neutral	0.129
OPA1	O60313-1.3	K116F	Pathogenic	0.556
OPA1	O60313-1.3	K116G	Pathogenic	0.617
OPA1	O60313-1.3	K116H	Neutral	0.39
OPA1	O60313-1.3	K116I	Pathogenic	0.543
OPA1	O60313-1.3	K116L	Neutral	0.31
OPA1	O60313-1.3	K116M	Neutral	0.193
OPA1	O60313-1.3	K116N	Neutral	0.284
OPA1	O60313-1.3	K116P	Neutral	0.252
OPA1	O60313-1.3	K116Q	Neutral	0.094
OPA1	O60313-1.3	K116R	Neutral	0.068
OPA1	O60313-1.3	K116S	Neutral	0.178
OPA1	O60313-1.3	K116T	Neutral	0.342
OPA1	O60313-1.3	K116V	Neutral	0.395
OPA1	O60313-1.3	K116W	Neutral	0.425
OPA1	O60313-1.3	K116Y	Neutral	0.475
OPA1	O60313-1.3	K117A	Pathogenic	0.886
OPA1	O60313-1.3	K117C	Pathogenic	0.974
OPA1	O60313-1.3	K117D	Pathogenic	0.958
OPA1	O60313-1.3	K117E	Pathogenic	0.72
OPA1	O60313-1.3	K117F	Pathogenic	0.956
OPA1	O60313-1.3	K117G	Pathogenic	0.965
OPA1	O60313-1.3	K117H	Pathogenic	0.917
OPA1	O60313-1.3	K117I	Pathogenic	0.954
OPA1	O60313-1.3	K117L	Pathogenic	0.886
OPA1	O60313-1.3	K117M	Pathogenic	0.805
OPA1	O60313-1.3	K117N	Pathogenic	0.873
OPA1	O60313-1.3	K117P	Pathogenic	0.853
OPA1	O60313-1.3	K117Q	Pathogenic	0.641
OPA1	O60313-1.3	K117R	Pathogenic	0.558
OPA1	O60313-1.3	K117S	Pathogenic	0.789
OPA1	O60313-1.3	K117T	Pathogenic	0.9
OPA1	O60313-1.3	K117V	Pathogenic	0.919
OPA1	O60313-1.3	K117W	Pathogenic	0.927
OPA1	O60313-1.3	K117Y	Pathogenic	0.94
OPA1	O60313-1.3	T118A	Neutral	0.361
OPA1	O60313-1.3	T118C	Neutral	0.487
OPA1	O60313-1.3	T118D	Neutral	0.423
OPA1	O60313-1.3	T118E	Neutral	0.44
OPA1	O60313-1.3	T118F	Pathogenic	0.535
OPA1	O60313-1.3	T118G	Pathogenic	0.786
OPA1	O60313-1.3	T118H	Pathogenic	0.817
OPA1	O60313-1.3	T118I	Neutral	0.29
OPA1	O60313-1.3	T118K	Neutral	0.341
OPA1	O60313-1.3	T118L	Neutral	0.31
OPA1	O60313-1.3	T118M	Neutral	0.408
OPA1	O60313-1.3	T118N	Neutral	0.227
OPA1	O60313-1.3	T118P	Pathogenic	0.551
OPA1	O60313-1.3	T118Q	Pathogenic	0.531
OPA1	O60313-1.3	T118R	Neutral	0.327
OPA1	O60313-1.3	T118S	Neutral	0.138
OPA1	O60313-1.3	T118V	Neutral	0.206
OPA1	O60313-1.3	T118W	Neutral	0.405
OPA1	O60313-1.3	T118Y	Pathogenic	0.706
OPA1	O60313-1.3	F119A	Neutral	0.332
OPA1	O60313-1.3	F119C	Neutral	0.497
OPA1	O60313-1.3	F119D	Neutral	0.37
OPA1	O60313-1.3	F119E	Neutral	0.415
OPA1	O60313-1.3	F119G	Pathogenic	0.503
OPA1	O60313-1.3	F119H	Neutral	0.15
OPA1	O60313-1.3	F119I	Neutral	0.219
OPA1	O60313-1.3	F119K	Neutral	0.362
OPA1	O60313-1.3	F119L	Neutral	0.207
OPA1	O60313-1.3	F119M	Neutral	0.146
OPA1	O60313-1.3	F119N	Neutral	0.411
OPA1	O60313-1.3	F119P	Pathogenic	0.869
OPA1	O60313-1.3	F119Q	Pathogenic	0.514
OPA1	O60313-1.3	F119R	Neutral	0.347
OPA1	O60313-1.3	F119S	Neutral	0.27
OPA1	O60313-1.3	F119T	Neutral	0.343
OPA1	O60313-1.3	F119V	Neutral	0.312
OPA1	O60313-1.3	F119W	Neutral	0.057
OPA1	O60313-1.3	F119Y	Neutral	0.006
OPA1	O60313-1.3	D120A	Pathogenic	0.519
OPA1	O60313-1.3	D120C	Pathogenic	0.644
OPA1	O60313-1.3	D120E	Neutral	0.036
OPA1	O60313-1.3	D120F	Neutral	0.428
OPA1	O60313-1.3	D120G	Neutral	0.315
OPA1	O60313-1.3	D120H	Neutral	0.302
OPA1	O60313-1.3	D120I	Neutral	0.435
OPA1	O60313-1.3	D120K	Neutral	0.431
OPA1	O60313-1.3	D120L	Pathogenic	0.71
OPA1	O60313-1.3	D120M	Pathogenic	0.565
OPA1	O60313-1.3	D120N	Neutral	0.098
OPA1	O60313-1.3	D120P	Neutral	0.218
OPA1	O60313-1.3	D120Q	Neutral	0.173
OPA1	O60313-1.3	D120R	Pathogenic	0.674
OPA1	O60313-1.3	D120S	Neutral	0.152
OPA1	O60313-1.3	D120T	Neutral	0.297
OPA1	O60313-1.3	D120V	Pathogenic	0.585
OPA1	O60313-1.3	D120W	Pathogenic	0.561
OPA1	O60313-1.3	D120Y	Pathogenic	0.61
OPA1	O60313-1.3	Q121A	Neutral	0.481
OPA1	O60313-1.3	Q121C	Pathogenic	0.818
OPA1	O60313-1.3	Q121D	Neutral	0.255
OPA1	O60313-1.3	Q121E	Neutral	0.047
OPA1	O60313-1.3	Q121F	Pathogenic	0.689
OPA1	O60313-1.3	Q121G	Pathogenic	0.768
OPA1	O60313-1.3	Q121H	Neutral	0.306
OPA1	O60313-1.3	Q121I	Pathogenic	0.694
OPA1	O60313-1.3	Q121K	Neutral	0.089
OPA1	O60313-1.3	Q121L	Neutral	0.463
OPA1	O60313-1.3	Q121M	Neutral	0.136
OPA1	O60313-1.3	Q121N	Neutral	0.289
OPA1	O60313-1.3	Q121P	Neutral	0.409
OPA1	O60313-1.3	Q121R	Neutral	0.084
OPA1	O60313-1.3	Q121S	Neutral	0.309
OPA1	O60313-1.3	Q121T	Pathogenic	0.517
OPA1	O60313-1.3	Q121V	Pathogenic	0.574
OPA1	O60313-1.3	Q121W	Neutral	0.31
OPA1	O60313-1.3	Q121Y	Neutral	0.354
OPA1	O60313-1.3	W122A	Pathogenic	0.958
OPA1	O60313-1.3	W122C	Pathogenic	0.94
OPA1	O60313-1.3	W122D	Pathogenic	0.964
OPA1	O60313-1.3	W122E	Pathogenic	0.918
OPA1	O60313-1.3	W122F	Pathogenic	0.616
OPA1	O60313-1.3	W122G	Pathogenic	0.846
OPA1	O60313-1.3	W122H	Pathogenic	0.889
OPA1	O60313-1.3	W122I	Pathogenic	0.991
OPA1	O60313-1.3	W122K	Pathogenic	0.899
OPA1	O60313-1.3	W122L	Pathogenic	0.972
OPA1	O60313-1.3	W122M	Pathogenic	0.886
OPA1	O60313-1.3	W122N	Pathogenic	0.97
OPA1	O60313-1.3	W122P	Pathogenic	0.99
OPA1	O60313-1.3	W122Q	Pathogenic	0.852
OPA1	O60313-1.3	W122R	Pathogenic	0.902
OPA1	O60313-1.3	W122S	Pathogenic	0.944
OPA1	O60313-1.3	W122T	Pathogenic	0.891
OPA1	O60313-1.3	W122V	Pathogenic	0.984
OPA1	O60313-1.3	W122Y	Neutral	0.209
OPA1	O60313-1.3	K123A	Pathogenic	0.725
OPA1	O60313-1.3	K123C	Pathogenic	0.928
OPA1	O60313-1.3	K123D	Pathogenic	0.886
OPA1	O60313-1.3	K123E	Neutral	0.466
OPA1	O60313-1.3	K123F	Pathogenic	0.881
OPA1	O60313-1.3	K123G	Pathogenic	0.904
OPA1	O60313-1.3	K123H	Pathogenic	0.79
OPA1	O60313-1.3	K123I	Pathogenic	0.875
OPA1	O60313-1.3	K123L	Pathogenic	0.726
OPA1	O60313-1.3	K123M	Pathogenic	0.584
OPA1	O60313-1.3	K123N	Pathogenic	0.7
OPA1	O60313-1.3	K123P	Pathogenic	0.664
OPA1	O60313-1.3	K123Q	Neutral	0.378
OPA1	O60313-1.3	K123R	Neutral	0.301
OPA1	O60313-1.3	K123S	Pathogenic	0.561
OPA1	O60313-1.3	K123T	Pathogenic	0.753
OPA1	O60313-1.3	K123V	Pathogenic	0.793
OPA1	O60313-1.3	K123W	Pathogenic	0.813
OPA1	O60313-1.3	K123Y	Pathogenic	0.842
OPA1	O60313-1.3	D124A	Pathogenic	0.706
OPA1	O60313-1.3	D124C	Pathogenic	0.801
OPA1	O60313-1.3	D124E	Neutral	0.076
OPA1	O60313-1.3	D124F	Pathogenic	0.625
OPA1	O60313-1.3	D124G	Pathogenic	0.506
OPA1	O60313-1.3	D124H	Neutral	0.49
OPA1	O60313-1.3	D124I	Pathogenic	0.631
OPA1	O60313-1.3	D124K	Pathogenic	0.628
OPA1	O60313-1.3	D124L	Pathogenic	0.845
OPA1	O60313-1.3	D124M	Pathogenic	0.743
OPA1	O60313-1.3	D124N	Neutral	0.196
OPA1	O60313-1.3	D124P	Neutral	0.383
OPA1	O60313-1.3	D124Q	Neutral	0.317
OPA1	O60313-1.3	D124R	Pathogenic	0.821
OPA1	O60313-1.3	D124S	Neutral	0.286
OPA1	O60313-1.3	D124T	Neutral	0.485
OPA1	O60313-1.3	D124V	Pathogenic	0.759
OPA1	O60313-1.3	D124W	Pathogenic	0.74
OPA1	O60313-1.3	D124Y	Pathogenic	0.777
OPA1	O60313-1.3	M125A	Neutral	0.317
OPA1	O60313-1.3	M125C	Neutral	0.48
OPA1	O60313-1.3	M125D	Pathogenic	0.614
OPA1	O60313-1.3	M125E	Neutral	0.398
OPA1	O60313-1.3	M125F	Neutral	0.21
OPA1	O60313-1.3	M125G	Pathogenic	0.732
OPA1	O60313-1.3	M125H	Pathogenic	0.581
OPA1	O60313-1.3	M125I	Neutral	0.086
OPA1	O60313-1.3	M125K	Neutral	0.144
OPA1	O60313-1.3	M125L	Neutral	0.034
OPA1	O60313-1.3	M125N	Neutral	0.395
OPA1	O60313-1.3	M125P	Pathogenic	0.681
OPA1	O60313-1.3	M125Q	Neutral	0.105
OPA1	O60313-1.3	M125R	Neutral	0.136
OPA1	O60313-1.3	M125S	Neutral	0.257
OPA1	O60313-1.3	M125T	Neutral	0.328
OPA1	O60313-1.3	M125V	Neutral	0.127
OPA1	O60313-1.3	M125W	Neutral	0.312
OPA1	O60313-1.3	M125Y	Neutral	0.494
OPA1	O60313-1.3	I126A	Neutral	0.043
OPA1	O60313-1.3	I126C	Neutral	0.082
OPA1	O60313-1.3	I126D	Neutral	0.133
OPA1	O60313-1.3	I126E	Neutral	0.156
OPA1	O60313-1.3	I126F	Neutral	0.066
OPA1	O60313-1.3	I126G	Neutral	0.433
OPA1	O60313-1.3	I126H	Neutral	0.279
OPA1	O60313-1.3	I126K	Neutral	0.12
OPA1	O60313-1.3	I126L	Neutral	0.008
OPA1	O60313-1.3	I126M	Neutral	0.015
OPA1	O60313-1.3	I126N	Neutral	0.154
OPA1	O60313-1.3	I126P	Neutral	0.373
OPA1	O60313-1.3	I126Q	Neutral	0.216
OPA1	O60313-1.3	I126R	Neutral	0.113
OPA1	O60313-1.3	I126S	Neutral	0.088
OPA1	O60313-1.3	I126T	Neutral	0.045
OPA1	O60313-1.3	I126V	Neutral	0.002
OPA1	O60313-1.3	I126W	Pathogenic	0.512
OPA1	O60313-1.3	I126Y	Neutral	0.086
OPA1	O60313-1.3	P127A	Pathogenic	0.988
OPA1	O60313-1.3	P127C	Pathogenic	0.999
OPA1	O60313-1.3	P127D	Pathogenic	0.97
OPA1	O60313-1.3	P127E	Pathogenic	0.971
OPA1	O60313-1.3	P127F	Pathogenic	0.999
OPA1	O60313-1.3	P127G	Pathogenic	0.994
OPA1	O60313-1.3	P127H	Pathogenic	0.995
OPA1	O60313-1.3	P127I	Pathogenic	0.997
OPA1	O60313-1.3	P127K	Pathogenic	0.957
OPA1	O60313-1.3	P127L	Pathogenic	0.997
OPA1	O60313-1.3	P127M	Pathogenic	0.995
OPA1	O60313-1.3	P127N	Pathogenic	0.991
OPA1	O60313-1.3	P127Q	Pathogenic	0.98
OPA1	O60313-1.3	P127R	Pathogenic	0.984
OPA1	O60313-1.3	P127S	Pathogenic	0.983
OPA1	O60313-1.3	P127T	Pathogenic	0.988
OPA1	O60313-1.3	P127V	Pathogenic	0.995
OPA1	O60313-1.3	P127W	Pathogenic	0.998
OPA1	O60313-1.3	P127Y	Pathogenic	0.999
OPA1	O60313-1.3	D128A	Pathogenic	0.979
OPA1	O60313-1.3	D128C	Pathogenic	0.987
OPA1	O60313-1.3	D128E	Pathogenic	0.617
OPA1	O60313-1.3	D128F	Pathogenic	0.97
OPA1	O60313-1.3	D128G	Pathogenic	0.952
OPA1	O60313-1.3	D128H	Pathogenic	0.949
OPA1	O60313-1.3	D128I	Pathogenic	0.971
OPA1	O60313-1.3	D128K	Pathogenic	0.971
OPA1	O60313-1.3	D128L	Pathogenic	0.991
OPA1	O60313-1.3	D128M	Pathogenic	0.983
OPA1	O60313-1.3	D128N	Pathogenic	0.826
OPA1	O60313-1.3	D128P	Pathogenic	0.924
OPA1	O60313-1.3	D128Q	Pathogenic	0.901
OPA1	O60313-1.3	D128R	Pathogenic	0.989
OPA1	O60313-1.3	D128S	Pathogenic	0.887
OPA1	O60313-1.3	D128T	Pathogenic	0.948
OPA1	O60313-1.3	D128V	Pathogenic	0.984
OPA1	O60313-1.3	D128W	Pathogenic	0.982
OPA1	O60313-1.3	D128Y	Pathogenic	0.985
OPA1	O60313-1.3	L129A	Neutral	0.141
OPA1	O60313-1.3	L129C	Neutral	0.247
OPA1	O60313-1.3	L129D	Pathogenic	0.621
OPA1	O60313-1.3	L129E	Neutral	0.405
OPA1	O60313-1.3	L129F	Neutral	0.182
OPA1	O60313-1.3	L129G	Pathogenic	0.738
OPA1	O60313-1.3	L129H	Pathogenic	0.588
OPA1	O60313-1.3	L129I	Neutral	0.027
OPA1	O60313-1.3	L129K	Neutral	0.147
OPA1	O60313-1.3	L129M	Neutral	0.019
OPA1	O60313-1.3	L129N	Neutral	0.402
OPA1	O60313-1.3	L129P	Pathogenic	0.687
OPA1	O60313-1.3	L129Q	Neutral	0.26
OPA1	O60313-1.3	L129R	Neutral	0.14
OPA1	O60313-1.3	L129S	Neutral	0.263
OPA1	O60313-1.3	L129T	Neutral	0.148
OPA1	O60313-1.3	L129V	Neutral	0.049
OPA1	O60313-1.3	L129W	Pathogenic	0.525
OPA1	O60313-1.3	L129Y	Neutral	0.258
OPA1	O60313-1.3	S130A	Neutral	0.024
OPA1	O60313-1.3	S130C	Neutral	0.097
OPA1	O60313-1.3	S130D	Neutral	0.045
OPA1	O60313-1.3	S130E	Neutral	0.047
OPA1	O60313-1.3	S130F	Neutral	0.11
OPA1	O60313-1.3	S130G	Neutral	0.08
OPA1	O60313-1.3	S130H	Neutral	0.172
OPA1	O60313-1.3	S130I	Neutral	0.113
OPA1	O60313-1.3	S130K	Neutral	0.032
OPA1	O60313-1.3	S130L	Neutral	0.123
OPA1	O60313-1.3	S130M	Neutral	0.069
OPA1	O60313-1.3	S130N	Neutral	0.018
OPA1	O60313-1.3	S130P	Neutral	0.119
OPA1	O60313-1.3	S130Q	Neutral	0.067
OPA1	O60313-1.3	S130R	Neutral	0.082
OPA1	O60313-1.3	S130T	Neutral	0.024
OPA1	O60313-1.3	S130V	Neutral	0.189
OPA1	O60313-1.3	S130W	Neutral	0.175
OPA1	O60313-1.3	S130Y	Neutral	0.205
OPA1	O60313-1.3	E131A	Neutral	0.062
OPA1	O60313-1.3	E131C	Neutral	0.483
OPA1	O60313-1.3	E131D	Neutral	0.006
OPA1	O60313-1.3	E131F	Neutral	0.132
OPA1	O60313-1.3	E131G	Neutral	0.192
OPA1	O60313-1.3	E131H	Neutral	0.029
OPA1	O60313-1.3	E131I	Neutral	0.135
OPA1	O60313-1.3	E131K	Neutral	0.014
OPA1	O60313-1.3	E131L	Neutral	0.147
OPA1	O60313-1.3	E131M	Neutral	0.084
OPA1	O60313-1.3	E131N	Neutral	0.055
OPA1	O60313-1.3	E131P	Neutral	0.047
OPA1	O60313-1.3	E131Q	Neutral	0.005
OPA1	O60313-1.3	E131R	Neutral	0.038
OPA1	O60313-1.3	E131S	Neutral	0.031
OPA1	O60313-1.3	E131T	Neutral	0.071
OPA1	O60313-1.3	E131V	Neutral	0.088
OPA1	O60313-1.3	E131W	Neutral	0.083
OPA1	O60313-1.3	E131Y	Neutral	0.099
OPA1	O60313-1.3	Y132A	Pathogenic	0.941
OPA1	O60313-1.3	Y132C	Pathogenic	0.968
OPA1	O60313-1.3	Y132D	Pathogenic	0.95
OPA1	O60313-1.3	Y132E	Pathogenic	0.888
OPA1	O60313-1.3	Y132F	Neutral	0.079
OPA1	O60313-1.3	Y132G	Pathogenic	0.97
OPA1	O60313-1.3	Y132H	Neutral	0.19
OPA1	O60313-1.3	Y132I	Pathogenic	0.852
OPA1	O60313-1.3	Y132K	Pathogenic	0.863
OPA1	O60313-1.3	Y132L	Pathogenic	0.864
OPA1	O60313-1.3	Y132M	Pathogenic	0.907
OPA1	O60313-1.3	Y132N	Pathogenic	0.886
OPA1	O60313-1.3	Y132P	Pathogenic	0.987
OPA1	O60313-1.3	Y132Q	Pathogenic	0.803
OPA1	O60313-1.3	Y132R	Pathogenic	0.861
OPA1	O60313-1.3	Y132S	Pathogenic	0.923
OPA1	O60313-1.3	Y132T	Pathogenic	0.944
OPA1	O60313-1.3	Y132V	Pathogenic	0.902
OPA1	O60313-1.3	Y132W	Neutral	0.133
OPA1	O60313-1.3	K133A	Neutral	0.164
OPA1	O60313-1.3	K133C	Neutral	0.488
OPA1	O60313-1.3	K133D	Neutral	0.365
OPA1	O60313-1.3	K133E	Neutral	0.061
OPA1	O60313-1.3	K133F	Neutral	0.354
OPA1	O60313-1.3	K133G	Neutral	0.412
OPA1	O60313-1.3	K133H	Neutral	0.218
OPA1	O60313-1.3	K133I	Neutral	0.342
OPA1	O60313-1.3	K133L	Neutral	0.164
OPA1	O60313-1.3	K133M	Neutral	0.094
OPA1	O60313-1.3	K133N	Neutral	0.148
OPA1	O60313-1.3	K133P	Neutral	0.128
OPA1	O60313-1.3	K133Q	Neutral	0.043
OPA1	O60313-1.3	K133R	Neutral	0.031
OPA1	O60313-1.3	K133S	Neutral	0.087
OPA1	O60313-1.3	K133T	Neutral	0.185
OPA1	O60313-1.3	K133V	Neutral	0.222
OPA1	O60313-1.3	K133W	Neutral	0.244
OPA1	O60313-1.3	K133Y	Neutral	0.283
OPA1	O60313-1.3	W134A	Pathogenic	0.987
OPA1	O60313-1.3	W134C	Pathogenic	0.982
OPA1	O60313-1.3	W134D	Pathogenic	0.989
OPA1	O60313-1.3	W134E	Pathogenic	0.975
OPA1	O60313-1.3	W134F	Pathogenic	0.846
OPA1	O60313-1.3	W134G	Pathogenic	0.95
OPA1	O60313-1.3	W134H	Pathogenic	0.965
OPA1	O60313-1.3	W134I	Pathogenic	0.997
OPA1	O60313-1.3	W134K	Pathogenic	0.968
OPA1	O60313-1.3	W134L	Pathogenic	0.992
OPA1	O60313-1.3	W134M	Pathogenic	0.964
OPA1	O60313-1.3	W134N	Pathogenic	0.991
OPA1	O60313-1.3	W134P	Pathogenic	0.997
OPA1	O60313-1.3	W134Q	Pathogenic	0.952
OPA1	O60313-1.3	W134R	Pathogenic	0.969
OPA1	O60313-1.3	W134S	Pathogenic	0.983
OPA1	O60313-1.3	W134T	Pathogenic	0.966
OPA1	O60313-1.3	W134V	Pathogenic	0.995
OPA1	O60313-1.3	W134Y	Neutral	0.476
OPA1	O60313-1.3	I135A	Neutral	0.102
OPA1	O60313-1.3	I135C	Neutral	0.185
OPA1	O60313-1.3	I135D	Neutral	0.281
OPA1	O60313-1.3	I135E	Neutral	0.32
OPA1	O60313-1.3	I135F	Neutral	0.153
OPA1	O60313-1.3	I135G	Pathogenic	0.661
OPA1	O60313-1.3	I135H	Neutral	0.497
OPA1	O60313-1.3	I135K	Neutral	0.258
OPA1	O60313-1.3	I135L	Neutral	0.02
OPA1	O60313-1.3	I135M	Neutral	0.038
OPA1	O60313-1.3	I135N	Neutral	0.317
OPA1	O60313-1.3	I135P	Pathogenic	0.603
OPA1	O60313-1.3	I135Q	Neutral	0.413
OPA1	O60313-1.3	I135R	Neutral	0.246
OPA1	O60313-1.3	I135S	Neutral	0.198
OPA1	O60313-1.3	I135T	Neutral	0.107
OPA1	O60313-1.3	I135V	Neutral	0.004
OPA1	O60313-1.3	I135W	Pathogenic	0.728
OPA1	O60313-1.3	I135Y	Neutral	0.194
OPA1	O60313-1.3	V136A	Neutral	0.09
OPA1	O60313-1.3	V136C	Neutral	0.362
OPA1	O60313-1.3	V136D	Neutral	0.495
OPA1	O60313-1.3	V136E	Neutral	0.283
OPA1	O60313-1.3	V136F	Neutral	0.286
OPA1	O60313-1.3	V136G	Pathogenic	0.628
OPA1	O60313-1.3	V136H	Pathogenic	0.692
OPA1	O60313-1.3	V136I	Neutral	0.006
OPA1	O60313-1.3	V136K	Neutral	0.206
OPA1	O60313-1.3	V136L	Neutral	0.051
OPA1	O60313-1.3	V136M	Neutral	0.076
OPA1	O60313-1.3	V136N	Pathogenic	0.538
OPA1	O60313-1.3	V136P	Pathogenic	0.568
OPA1	O60313-1.3	V136Q	Neutral	0.363
OPA1	O60313-1.3	V136R	Neutral	0.415
OPA1	O60313-1.3	V136S	Neutral	0.382
OPA1	O60313-1.3	V136T	Neutral	0.094
OPA1	O60313-1.3	V136W	Pathogenic	0.665
OPA1	O60313-1.3	V136Y	Neutral	0.343
OPA1	O60313-1.3	P137A	Neutral	0.476
OPA1	O60313-1.3	P137C	Pathogenic	0.904
OPA1	O60313-1.3	P137D	Neutral	0.269
OPA1	O60313-1.3	P137E	Neutral	0.28
OPA1	O60313-1.3	P137F	Pathogenic	0.918
OPA1	O60313-1.3	P137G	Pathogenic	0.649
OPA1	O60313-1.3	P137H	Pathogenic	0.688
OPA1	O60313-1.3	P137I	Pathogenic	0.798
OPA1	O60313-1.3	P137K	Neutral	0.203
OPA1	O60313-1.3	P137L	Pathogenic	0.813
OPA1	O60313-1.3	P137M	Pathogenic	0.697
OPA1	O60313-1.3	P137N	Pathogenic	0.55
OPA1	O60313-1.3	P137Q	Neutral	0.358
OPA1	O60313-1.3	P137R	Neutral	0.41
OPA1	O60313-1.3	P137S	Neutral	0.404
OPA1	O60313-1.3	P137T	Neutral	0.483
OPA1	O60313-1.3	P137V	Pathogenic	0.715
OPA1	O60313-1.3	P137W	Pathogenic	0.868
OPA1	O60313-1.3	P137Y	Pathogenic	0.889
OPA1	O60313-1.3	D138A	Pathogenic	0.909
OPA1	O60313-1.3	D138C	Pathogenic	0.944
OPA1	O60313-1.3	D138E	Neutral	0.255
OPA1	O60313-1.3	D138F	Pathogenic	0.873
OPA1	O60313-1.3	D138G	Pathogenic	0.809
OPA1	O60313-1.3	D138H	Pathogenic	0.799
OPA1	O60313-1.3	D138I	Pathogenic	0.876
OPA1	O60313-1.3	D138K	Pathogenic	0.875
OPA1	O60313-1.3	D138L	Pathogenic	0.958
OPA1	O60313-1.3	D138M	Pathogenic	0.923
OPA1	O60313-1.3	D138N	Pathogenic	0.502
OPA1	O60313-1.3	D138P	Pathogenic	0.72
OPA1	O60313-1.3	D138Q	Pathogenic	0.658
OPA1	O60313-1.3	D138R	Pathogenic	0.95
OPA1	O60313-1.3	D138S	Pathogenic	0.624
OPA1	O60313-1.3	D138T	Pathogenic	0.796
OPA1	O60313-1.3	D138V	Pathogenic	0.929
OPA1	O60313-1.3	D138W	Pathogenic	0.922
OPA1	O60313-1.3	D138Y	Pathogenic	0.935
OPA1	O60313-1.3	I139A	Neutral	0.022
OPA1	O60313-1.3	I139C	Neutral	0.042
OPA1	O60313-1.3	I139D	Neutral	0.07
OPA1	O60313-1.3	I139E	Neutral	0.084
OPA1	O60313-1.3	I139F	Neutral	0.034
OPA1	O60313-1.3	I139G	Neutral	0.274
OPA1	O60313-1.3	I139H	Neutral	0.16
OPA1	O60313-1.3	I139K	Neutral	0.063
OPA1	O60313-1.3	I139L	Neutral	0.004
OPA1	O60313-1.3	I139M	Neutral	0.007
OPA1	O60313-1.3	I139N	Neutral	0.082
OPA1	O60313-1.3	I139P	Neutral	0.227
OPA1	O60313-1.3	I139Q	Neutral	0.12
OPA1	O60313-1.3	I139R	Neutral	0.059
OPA1	O60313-1.3	I139S	Neutral	0.045
OPA1	O60313-1.3	I139T	Neutral	0.023
OPA1	O60313-1.3	I139V	Neutral	0.001
OPA1	O60313-1.3	I139W	Neutral	0.341
OPA1	O60313-1.3	I139Y	Neutral	0.044
OPA1	O60313-1.3	V140A	Neutral	0.019
OPA1	O60313-1.3	V140C	Neutral	0.098
OPA1	O60313-1.3	V140D	Neutral	0.158
OPA1	O60313-1.3	V140E	Neutral	0.07
OPA1	O60313-1.3	V140F	Neutral	0.071
OPA1	O60313-1.3	V140G	Neutral	0.244
OPA1	O60313-1.3	V140H	Neutral	0.301
OPA1	O60313-1.3	V140I	Neutral	0.001
OPA1	O60313-1.3	V140K	Neutral	0.047
OPA1	O60313-1.3	V140L	Neutral	0.01
OPA1	O60313-1.3	V140M	Neutral	0.016
OPA1	O60313-1.3	V140N	Neutral	0.182
OPA1	O60313-1.3	V140P	Neutral	0.201
OPA1	O60313-1.3	V140Q	Neutral	0.098
OPA1	O60313-1.3	V140R	Neutral	0.12
OPA1	O60313-1.3	V140S	Neutral	0.106
OPA1	O60313-1.3	V140T	Neutral	0.019
OPA1	O60313-1.3	V140W	Neutral	0.276
OPA1	O60313-1.3	V140Y	Neutral	0.091
OPA1	O60313-1.3	W141A	Pathogenic	0.832
OPA1	O60313-1.3	W141C	Pathogenic	0.773
OPA1	O60313-1.3	W141D	Pathogenic	0.855
OPA1	O60313-1.3	W141E	Pathogenic	0.71
OPA1	O60313-1.3	W141F	Neutral	0.26
OPA1	O60313-1.3	W141G	Pathogenic	0.546
OPA1	O60313-1.3	W141H	Pathogenic	0.638
OPA1	O60313-1.3	W141I	Pathogenic	0.96
OPA1	O60313-1.3	W141K	Pathogenic	0.661
OPA1	O60313-1.3	W141L	Pathogenic	0.884
OPA1	O60313-1.3	W141M	Pathogenic	0.63
OPA1	O60313-1.3	W141N	Pathogenic	0.875
OPA1	O60313-1.3	W141P	Pathogenic	0.958
OPA1	O60313-1.3	W141Q	Pathogenic	0.557
OPA1	O60313-1.3	W141R	Pathogenic	0.669
OPA1	O60313-1.3	W141S	Pathogenic	0.787
OPA1	O60313-1.3	W141T	Pathogenic	0.643
OPA1	O60313-1.3	W141V	Pathogenic	0.929
OPA1	O60313-1.3	W141Y	Neutral	0.055
OPA1	O60313-1.3	E142A	Neutral	0.193
OPA1	O60313-1.3	E142C	Pathogenic	0.771
OPA1	O60313-1.3	E142D	Neutral	0.022
OPA1	O60313-1.3	E142F	Neutral	0.355
OPA1	O60313-1.3	E142G	Neutral	0.461
OPA1	O60313-1.3	E142H	Neutral	0.099
OPA1	O60313-1.3	E142I	Neutral	0.361
OPA1	O60313-1.3	E142K	Neutral	0.049
OPA1	O60313-1.3	E142L	Neutral	0.383
OPA1	O60313-1.3	E142M	Neutral	0.248
OPA1	O60313-1.3	E142N	Neutral	0.174
OPA1	O60313-1.3	E142P	Neutral	0.152
OPA1	O60313-1.3	E142Q	Neutral	0.018
OPA1	O60313-1.3	E142R	Neutral	0.124
OPA1	O60313-1.3	E142S	Neutral	0.104
OPA1	O60313-1.3	E142T	Neutral	0.216
OPA1	O60313-1.3	E142V	Neutral	0.258
OPA1	O60313-1.3	E142W	Neutral	0.245
OPA1	O60313-1.3	E142Y	Neutral	0.284
OPA1	O60313-1.3	I143A	Neutral	0.006
OPA1	O60313-1.3	I143C	Neutral	0.012
OPA1	O60313-1.3	I143D	Neutral	0.021
OPA1	O60313-1.3	I143E	Neutral	0.025
OPA1	O60313-1.3	I143F	Neutral	0.01
OPA1	O60313-1.3	I143G	Neutral	0.097
OPA1	O60313-1.3	I143H	Neutral	0.052
OPA1	O60313-1.3	I143K	Neutral	0.019
OPA1	O60313-1.3	I143L	Neutral	0.001
OPA1	O60313-1.3	I143M	Neutral	0.002
OPA1	O60313-1.3	I143N	Neutral	0.025
OPA1	O60313-1.3	I143P	Neutral	0.078
OPA1	O60313-1.3	I143Q	Neutral	0.037
OPA1	O60313-1.3	I143R	Neutral	0.018
OPA1	O60313-1.3	I143S	Neutral	0.013
OPA1	O60313-1.3	I143T	Neutral	0.007
OPA1	O60313-1.3	I143V	Neutral	0.0
OPA1	O60313-1.3	I143W	Neutral	0.129
OPA1	O60313-1.3	I143Y	Neutral	0.013
OPA1	O60313-1.3	D144A	Neutral	0.159
OPA1	O60313-1.3	D144C	Neutral	0.241
OPA1	O60313-1.3	D144E	Neutral	0.006
OPA1	O60313-1.3	D144F	Neutral	0.116
OPA1	O60313-1.3	D144G	Neutral	0.074
OPA1	O60313-1.3	D144H	Neutral	0.07
OPA1	O60313-1.3	D144I	Neutral	0.119
OPA1	O60313-1.3	D144K	Neutral	0.117
OPA1	O60313-1.3	D144L	Neutral	0.3
OPA1	O60313-1.3	D144M	Neutral	0.185
OPA1	O60313-1.3	D144N	Neutral	0.019
OPA1	O60313-1.3	D144P	Neutral	0.046
OPA1	O60313-1.3	D144Q	Neutral	0.035
OPA1	O60313-1.3	D144R	Neutral	0.265
OPA1	O60313-1.3	D144S	Neutral	0.031
OPA1	O60313-1.3	D144T	Neutral	0.069
OPA1	O60313-1.3	D144V	Neutral	0.198
OPA1	O60313-1.3	D144W	Neutral	0.183
OPA1	O60313-1.3	D144Y	Neutral	0.215
OPA1	O60313-1.3	E145A	Neutral	0.098
OPA1	O60313-1.3	E145C	Pathogenic	0.605
OPA1	O60313-1.3	E145D	Neutral	0.01
OPA1	O60313-1.3	E145F	Neutral	0.2
OPA1	O60313-1.3	E145G	Neutral	0.28
OPA1	O60313-1.3	E145H	Neutral	0.047
OPA1	O60313-1.3	E145I	Neutral	0.204
OPA1	O60313-1.3	E145K	Neutral	0.023
OPA1	O60313-1.3	E145L	Neutral	0.22
OPA1	O60313-1.3	E145M	Neutral	0.13
OPA1	O60313-1.3	E145N	Neutral	0.087
OPA1	O60313-1.3	E145P	Neutral	0.075
OPA1	O60313-1.3	E145Q	Neutral	0.008
OPA1	O60313-1.3	E145R	Neutral	0.06
OPA1	O60313-1.3	E145S	Neutral	0.05
OPA1	O60313-1.3	E145T	Neutral	0.111
OPA1	O60313-1.3	E145V	Neutral	0.136
OPA1	O60313-1.3	E145W	Neutral	0.128
OPA1	O60313-1.3	E145Y	Neutral	0.152
OPA1	O60313-1.3	Y146A	Neutral	0.028
OPA1	O60313-1.3	Y146C	Neutral	0.051
OPA1	O60313-1.3	Y146D	Neutral	0.032
OPA1	O60313-1.3	Y146E	Neutral	0.014
OPA1	O60313-1.3	Y146F	Neutral	0.0
OPA1	O60313-1.3	Y146G	Neutral	0.055
OPA1	O60313-1.3	Y146H	Neutral	0.0
OPA1	O60313-1.3	Y146I	Neutral	0.01
OPA1	O60313-1.3	Y146K	Neutral	0.011
OPA1	O60313-1.3	Y146L	Neutral	0.011
OPA1	O60313-1.3	Y146M	Neutral	0.017
OPA1	O60313-1.3	Y146N	Neutral	0.014
OPA1	O60313-1.3	Y146P	Neutral	0.115
OPA1	O60313-1.3	Y146Q	Neutral	0.007
OPA1	O60313-1.3	Y146R	Neutral	0.011
OPA1	O60313-1.3	Y146S	Neutral	0.021
OPA1	O60313-1.3	Y146T	Neutral	0.029
OPA1	O60313-1.3	Y146V	Neutral	0.016
OPA1	O60313-1.3	Y146W	Neutral	0.0
OPA1	O60313-1.3	I147A	Neutral	0.047
OPA1	O60313-1.3	I147C	Neutral	0.089
OPA1	O60313-1.3	I147D	Neutral	0.143
OPA1	O60313-1.3	I147E	Neutral	0.168
OPA1	O60313-1.3	I147F	Neutral	0.072
OPA1	O60313-1.3	I147G	Neutral	0.455
OPA1	O60313-1.3	I147H	Neutral	0.297
OPA1	O60313-1.3	I147K	Neutral	0.129
OPA1	O60313-1.3	I147L	Neutral	0.009
OPA1	O60313-1.3	I147M	Neutral	0.016
OPA1	O60313-1.3	I147N	Neutral	0.166
OPA1	O60313-1.3	I147P	Neutral	0.394
OPA1	O60313-1.3	I147Q	Neutral	0.232
OPA1	O60313-1.3	I147R	Neutral	0.123
OPA1	O60313-1.3	I147S	Neutral	0.096
OPA1	O60313-1.3	I147T	Neutral	0.049
OPA1	O60313-1.3	I147V	Neutral	0.002
OPA1	O60313-1.3	I147W	Pathogenic	0.534
OPA1	O60313-1.3	I147Y	Neutral	0.093
OPA1	O60313-1.3	D148A	Pathogenic	0.895
OPA1	O60313-1.3	D148C	Pathogenic	0.935
OPA1	O60313-1.3	D148E	Neutral	0.227
OPA1	O60313-1.3	D148F	Pathogenic	0.856
OPA1	O60313-1.3	D148G	Pathogenic	0.785
OPA1	O60313-1.3	D148H	Pathogenic	0.774
OPA1	O60313-1.3	D148I	Pathogenic	0.859
OPA1	O60313-1.3	D148K	Pathogenic	0.857
OPA1	O60313-1.3	D148L	Pathogenic	0.951
OPA1	O60313-1.3	D148M	Pathogenic	0.912
OPA1	O60313-1.3	D148N	Neutral	0.464
OPA1	O60313-1.3	D148P	Pathogenic	0.688
OPA1	O60313-1.3	D148Q	Pathogenic	0.624
OPA1	O60313-1.3	D148R	Pathogenic	0.942
OPA1	O60313-1.3	D148S	Pathogenic	0.588
OPA1	O60313-1.3	D148T	Pathogenic	0.771
OPA1	O60313-1.3	D148V	Pathogenic	0.918
OPA1	O60313-1.3	D148W	Pathogenic	0.91
OPA1	O60313-1.3	D148Y	Pathogenic	0.925
OPA1	O60313-1.3	F149A	Neutral	0.182
OPA1	O60313-1.3	F149C	Neutral	0.307
OPA1	O60313-1.3	F149D	Neutral	0.208
OPA1	O60313-1.3	F149E	Neutral	0.241
OPA1	O60313-1.3	F149G	Neutral	0.312
OPA1	O60313-1.3	F149H	Neutral	0.073
OPA1	O60313-1.3	F149I	Neutral	0.111
OPA1	O60313-1.3	F149K	Neutral	0.202
OPA1	O60313-1.3	F149L	Neutral	0.105
OPA1	O60313-1.3	F149M	Neutral	0.071
OPA1	O60313-1.3	F149N	Neutral	0.238
OPA1	O60313-1.3	F149P	Pathogenic	0.748
OPA1	O60313-1.3	F149Q	Neutral	0.321
OPA1	O60313-1.3	F149R	Neutral	0.192
OPA1	O60313-1.3	F149S	Neutral	0.142
OPA1	O60313-1.3	F149T	Neutral	0.189
OPA1	O60313-1.3	F149V	Neutral	0.169
OPA1	O60313-1.3	F149W	Neutral	0.026
OPA1	O60313-1.3	F149Y	Neutral	0.002
OPA1	O60313-1.3	E150A	Neutral	0.05
OPA1	O60313-1.3	E150C	Neutral	0.424
OPA1	O60313-1.3	E150D	Neutral	0.005
OPA1	O60313-1.3	E150F	Neutral	0.107
OPA1	O60313-1.3	E150G	Neutral	0.157
OPA1	O60313-1.3	E150H	Neutral	0.023
OPA1	O60313-1.3	E150I	Neutral	0.11
OPA1	O60313-1.3	E150K	Neutral	0.011
OPA1	O60313-1.3	E150L	Neutral	0.119
OPA1	O60313-1.3	E150M	Neutral	0.067
OPA1	O60313-1.3	E150N	Neutral	0.044
OPA1	O60313-1.3	E150P	Neutral	0.038
OPA1	O60313-1.3	E150Q	Neutral	0.004
OPA1	O60313-1.3	E150R	Neutral	0.03
OPA1	O60313-1.3	E150S	Neutral	0.025
OPA1	O60313-1.3	E150T	Neutral	0.057
OPA1	O60313-1.3	E150V	Neutral	0.07
OPA1	O60313-1.3	E150W	Neutral	0.066
OPA1	O60313-1.3	E150Y	Neutral	0.079
OPA1	O60313-1.3	K151A	Neutral	0.428
OPA1	O60313-1.3	K151C	Pathogenic	0.785
OPA1	O60313-1.3	K151D	Pathogenic	0.687
OPA1	O60313-1.3	K151E	Neutral	0.199
OPA1	O60313-1.3	K151F	Pathogenic	0.677
OPA1	O60313-1.3	K151G	Pathogenic	0.729
OPA1	O60313-1.3	K151H	Pathogenic	0.516
OPA1	O60313-1.3	K151I	Pathogenic	0.665
OPA1	O60313-1.3	K151L	Neutral	0.429
OPA1	O60313-1.3	K151M	Neutral	0.285
OPA1	O60313-1.3	K151N	Neutral	0.398
OPA1	O60313-1.3	K151P	Neutral	0.359
OPA1	O60313-1.3	K151Q	Neutral	0.147
OPA1	O60313-1.3	K151R	Neutral	0.109
OPA1	O60313-1.3	K151S	Neutral	0.266
OPA1	O60313-1.3	K151T	Neutral	0.464
OPA1	O60313-1.3	K151V	Pathogenic	0.521
OPA1	O60313-1.3	K151W	Pathogenic	0.553
OPA1	O60313-1.3	K151Y	Pathogenic	0.601
OPA1	O60313-1.3	I152A	Neutral	0.103
OPA1	O60313-1.3	I152C	Neutral	0.187
OPA1	O60313-1.3	I152D	Neutral	0.283
OPA1	O60313-1.3	I152E	Neutral	0.323
OPA1	O60313-1.3	I152F	Neutral	0.155
OPA1	O60313-1.3	I152G	Pathogenic	0.664
OPA1	O60313-1.3	I152H	Neutral	0.5
OPA1	O60313-1.3	I152K	Neutral	0.26
OPA1	O60313-1.3	I152L	Neutral	0.021
OPA1	O60313-1.3	I152M	Neutral	0.038
OPA1	O60313-1.3	I152N	Neutral	0.32
OPA1	O60313-1.3	I152P	Pathogenic	0.606
OPA1	O60313-1.3	I152Q	Neutral	0.416
OPA1	O60313-1.3	I152R	Neutral	0.248
OPA1	O60313-1.3	I152S	Neutral	0.2
OPA1	O60313-1.3	I152T	Neutral	0.108
OPA1	O60313-1.3	I152V	Neutral	0.004
OPA1	O60313-1.3	I152W	Pathogenic	0.73
OPA1	O60313-1.3	I152Y	Neutral	0.196
OPA1	O60313-1.3	R153A	Neutral	0.001
OPA1	O60313-1.3	R153C	Neutral	0.005
OPA1	O60313-1.3	R153D	Neutral	0.008
OPA1	O60313-1.3	R153E	Neutral	0.001
OPA1	O60313-1.3	R153F	Neutral	0.003
OPA1	O60313-1.3	R153G	Neutral	0.004
OPA1	O60313-1.3	R153H	Neutral	0.0
OPA1	O60313-1.3	R153I	Neutral	0.003
OPA1	O60313-1.3	R153K	Neutral	0.0
OPA1	O60313-1.3	R153L	Neutral	0.001
OPA1	O60313-1.3	R153M	Neutral	0.001
OPA1	O60313-1.3	R153N	Neutral	0.001
OPA1	O60313-1.3	R153P	Neutral	0.002
OPA1	O60313-1.3	R153Q	Neutral	0.0
OPA1	O60313-1.3	R153S	Neutral	0.001
OPA1	O60313-1.3	R153T	Neutral	0.001
OPA1	O60313-1.3	R153V	Neutral	0.004
OPA1	O60313-1.3	R153W	Neutral	0.002
OPA1	O60313-1.3	R153Y	Neutral	0.002
OPA1	O60313-1.3	K154A	Neutral	0.04
OPA1	O60313-1.3	K154C	Neutral	0.168
OPA1	O60313-1.3	K154D	Neutral	0.108
OPA1	O60313-1.3	K154E	Neutral	0.014
OPA1	O60313-1.3	K154F	Neutral	0.104
OPA1	O60313-1.3	K154G	Neutral	0.129
OPA1	O60313-1.3	K154H	Neutral	0.056
OPA1	O60313-1.3	K154I	Neutral	0.099
OPA1	O60313-1.3	K154L	Neutral	0.04
OPA1	O60313-1.3	K154M	Neutral	0.022
OPA1	O60313-1.3	K154N	Neutral	0.035
OPA1	O60313-1.3	K154P	Neutral	0.03
OPA1	O60313-1.3	K154Q	Neutral	0.009
OPA1	O60313-1.3	K154R	Neutral	0.007
OPA1	O60313-1.3	K154S	Neutral	0.02
OPA1	O60313-1.3	K154T	Neutral	0.046
OPA1	O60313-1.3	K154V	Neutral	0.057
OPA1	O60313-1.3	K154W	Neutral	0.064
OPA1	O60313-1.3	K154Y	Neutral	0.077
OPA1	O60313-1.3	A155C	Neutral	0.013
OPA1	O60313-1.3	A155D	Neutral	0.068
OPA1	O60313-1.3	A155E	Neutral	0.026
OPA1	O60313-1.3	A155F	Neutral	0.041
OPA1	O60313-1.3	A155G	Neutral	0.018
OPA1	O60313-1.3	A155H	Neutral	0.131
OPA1	O60313-1.3	A155I	Neutral	0.015
OPA1	O60313-1.3	A155K	Neutral	0.017
OPA1	O60313-1.3	A155L	Neutral	0.016
OPA1	O60313-1.3	A155M	Neutral	0.025
OPA1	O60313-1.3	A155N	Neutral	0.077
OPA1	O60313-1.3	A155P	Neutral	0.044
OPA1	O60313-1.3	A155Q	Neutral	0.037
OPA1	O60313-1.3	A155R	Neutral	0.016
OPA1	O60313-1.3	A155S	Neutral	0.006
OPA1	O60313-1.3	A155T	Neutral	0.022
OPA1	O60313-1.3	A155V	Neutral	0.01
OPA1	O60313-1.3	A155W	Neutral	0.068
OPA1	O60313-1.3	A155Y	Neutral	0.082
OPA1	O60313-1.3	L156A	Neutral	0.116
OPA1	O60313-1.3	L156C	Neutral	0.208
OPA1	O60313-1.3	L156D	Pathogenic	0.567
OPA1	O60313-1.3	L156E	Neutral	0.353
OPA1	O60313-1.3	L156F	Neutral	0.151
OPA1	O60313-1.3	L156G	Pathogenic	0.693
OPA1	O60313-1.3	L156H	Pathogenic	0.533
OPA1	O60313-1.3	L156I	Neutral	0.021
OPA1	O60313-1.3	L156K	Neutral	0.121
OPA1	O60313-1.3	L156M	Neutral	0.015
OPA1	O60313-1.3	L156N	Neutral	0.349
OPA1	O60313-1.3	L156P	Pathogenic	0.637
OPA1	O60313-1.3	L156Q	Neutral	0.219
OPA1	O60313-1.3	L156R	Neutral	0.115
OPA1	O60313-1.3	L156S	Neutral	0.222
OPA1	O60313-1.3	L156T	Neutral	0.122
OPA1	O60313-1.3	L156V	Neutral	0.04
OPA1	O60313-1.3	L156W	Neutral	0.469
OPA1	O60313-1.3	L156Y	Neutral	0.217
OPA1	O60313-1.3	P157A	Neutral	0.399
OPA1	O60313-1.3	P157C	Pathogenic	0.873
OPA1	O60313-1.3	P157D	Neutral	0.212
OPA1	O60313-1.3	P157E	Neutral	0.221
OPA1	O60313-1.3	P157F	Pathogenic	0.891
OPA1	O60313-1.3	P157G	Pathogenic	0.575
OPA1	O60313-1.3	P157H	Pathogenic	0.617
OPA1	O60313-1.3	P157I	Pathogenic	0.743
OPA1	O60313-1.3	P157K	Neutral	0.157
OPA1	O60313-1.3	P157L	Pathogenic	0.76
OPA1	O60313-1.3	P157M	Pathogenic	0.627
OPA1	O60313-1.3	P157N	Neutral	0.472
OPA1	O60313-1.3	P157Q	Neutral	0.29
OPA1	O60313-1.3	P157R	Neutral	0.337
OPA1	O60313-1.3	P157S	Neutral	0.331
OPA1	O60313-1.3	P157T	Neutral	0.406
OPA1	O60313-1.3	P157V	Pathogenic	0.647
OPA1	O60313-1.3	P157W	Pathogenic	0.828
OPA1	O60313-1.3	P157Y	Pathogenic	0.854
OPA1	O60313-1.3	S158A	Neutral	0.0
OPA1	O60313-1.3	S158C	Neutral	0.002
OPA1	O60313-1.3	S158D	Neutral	0.001
OPA1	O60313-1.3	S158E	Neutral	0.001
OPA1	O60313-1.3	S158F	Neutral	0.002
OPA1	O60313-1.3	S158G	Neutral	0.001
OPA1	O60313-1.3	S158H	Neutral	0.003
OPA1	O60313-1.3	S158I	Neutral	0.002
OPA1	O60313-1.3	S158K	Neutral	0.001
OPA1	O60313-1.3	S158L	Neutral	0.002
OPA1	O60313-1.3	S158M	Neutral	0.001
OPA1	O60313-1.3	S158N	Neutral	0.0
OPA1	O60313-1.3	S158P	Neutral	0.002
OPA1	O60313-1.3	S158Q	Neutral	0.001
OPA1	O60313-1.3	S158R	Neutral	0.001
OPA1	O60313-1.3	S158T	Neutral	0.0
OPA1	O60313-1.3	S158V	Neutral	0.004
OPA1	O60313-1.3	S158W	Neutral	0.003
OPA1	O60313-1.3	S158Y	Neutral	0.004
OPA1	O60313-1.3	S159A	Neutral	0.001
OPA1	O60313-1.3	S159C	Neutral	0.003
OPA1	O60313-1.3	S159D	Neutral	0.002
OPA1	O60313-1.3	S159E	Neutral	0.002
OPA1	O60313-1.3	S159F	Neutral	0.004
OPA1	O60313-1.3	S159G	Neutral	0.003
OPA1	O60313-1.3	S159H	Neutral	0.007
OPA1	O60313-1.3	S159I	Neutral	0.004
OPA1	O60313-1.3	S159K	Neutral	0.001
OPA1	O60313-1.3	S159L	Neutral	0.004
OPA1	O60313-1.3	S159M	Neutral	0.002
OPA1	O60313-1.3	S159N	Neutral	0.001
OPA1	O60313-1.3	S159P	Neutral	0.004
OPA1	O60313-1.3	S159Q	Neutral	0.002
OPA1	O60313-1.3	S159R	Neutral	0.003
OPA1	O60313-1.3	S159T	Neutral	0.001
OPA1	O60313-1.3	S159V	Neutral	0.007
OPA1	O60313-1.3	S159W	Neutral	0.007
OPA1	O60313-1.3	S159Y	Neutral	0.008
OPA1	O60313-1.3	E160A	Neutral	0.022
OPA1	O60313-1.3	E160C	Neutral	0.239
OPA1	O60313-1.3	E160D	Neutral	0.002
OPA1	O60313-1.3	E160F	Neutral	0.049
OPA1	O60313-1.3	E160G	Neutral	0.074
OPA1	O60313-1.3	E160H	Neutral	0.01
OPA1	O60313-1.3	E160I	Neutral	0.05
OPA1	O60313-1.3	E160K	Neutral	0.005
OPA1	O60313-1.3	E160L	Neutral	0.055
OPA1	O60313-1.3	E160M	Neutral	0.03
OPA1	O60313-1.3	E160N	Neutral	0.019
OPA1	O60313-1.3	E160P	Neutral	0.016
OPA1	O60313-1.3	E160Q	Neutral	0.002
OPA1	O60313-1.3	E160R	Neutral	0.013
OPA1	O60313-1.3	E160S	Neutral	0.011
OPA1	O60313-1.3	E160T	Neutral	0.025
OPA1	O60313-1.3	E160V	Neutral	0.031
OPA1	O60313-1.3	E160W	Neutral	0.029
OPA1	O60313-1.3	E160Y	Neutral	0.036
OPA1	O60313-1.3	D161A	Neutral	0.361
OPA1	O60313-1.3	D161C	Neutral	0.487
OPA1	O60313-1.3	D161E	Neutral	0.019
OPA1	O60313-1.3	D161F	Neutral	0.282
OPA1	O60313-1.3	D161G	Neutral	0.194
OPA1	O60313-1.3	D161H	Neutral	0.185
OPA1	O60313-1.3	D161I	Neutral	0.287
OPA1	O60313-1.3	D161K	Neutral	0.284
OPA1	O60313-1.3	D161L	Pathogenic	0.562
OPA1	O60313-1.3	D161M	Neutral	0.405
OPA1	O60313-1.3	D161N	Neutral	0.054
OPA1	O60313-1.3	D161P	Neutral	0.127
OPA1	O60313-1.3	D161Q	Neutral	0.099
OPA1	O60313-1.3	D161R	Pathogenic	0.52
OPA1	O60313-1.3	D161S	Neutral	0.086
OPA1	O60313-1.3	D161T	Neutral	0.182
OPA1	O60313-1.3	D161V	Neutral	0.426
OPA1	O60313-1.3	D161W	Neutral	0.402
OPA1	O60313-1.3	D161Y	Neutral	0.45
OPA1	O60313-1.3	L162A	Neutral	0.066
OPA1	O60313-1.3	L162C	Neutral	0.123
OPA1	O60313-1.3	L162D	Neutral	0.411
OPA1	O60313-1.3	L162E	Neutral	0.225
OPA1	O60313-1.3	L162F	Neutral	0.087
OPA1	O60313-1.3	L162G	Pathogenic	0.546
OPA1	O60313-1.3	L162H	Neutral	0.378
OPA1	O60313-1.3	L162I	Neutral	0.012
OPA1	O60313-1.3	L162K	Neutral	0.069
OPA1	O60313-1.3	L162M	Neutral	0.008
OPA1	O60313-1.3	L162N	Neutral	0.223
OPA1	O60313-1.3	L162P	Neutral	0.484
OPA1	O60313-1.3	L162Q	Neutral	0.13
OPA1	O60313-1.3	L162R	Neutral	0.065
OPA1	O60313-1.3	L162S	Neutral	0.132
OPA1	O60313-1.3	L162T	Neutral	0.069
OPA1	O60313-1.3	L162V	Neutral	0.022
OPA1	O60313-1.3	L162W	Neutral	0.321
OPA1	O60313-1.3	L162Y	Neutral	0.129
OPA1	O60313-1.3	V163A	Neutral	0.02
OPA1	O60313-1.3	V163C	Neutral	0.105
OPA1	O60313-1.3	V163D	Neutral	0.168
OPA1	O60313-1.3	V163E	Neutral	0.075
OPA1	O60313-1.3	V163F	Neutral	0.076
OPA1	O60313-1.3	V163G	Neutral	0.258
OPA1	O60313-1.3	V163H	Neutral	0.316
OPA1	O60313-1.3	V163I	Neutral	0.001
OPA1	O60313-1.3	V163K	Neutral	0.051
OPA1	O60313-1.3	V163L	Neutral	0.011
OPA1	O60313-1.3	V163M	Neutral	0.017
OPA1	O60313-1.3	V163N	Neutral	0.193
OPA1	O60313-1.3	V163P	Neutral	0.213
OPA1	O60313-1.3	V163Q	Neutral	0.105
OPA1	O60313-1.3	V163R	Neutral	0.127
OPA1	O60313-1.3	V163S	Neutral	0.113
OPA1	O60313-1.3	V163T	Neutral	0.021
OPA1	O60313-1.3	V163W	Neutral	0.29
OPA1	O60313-1.3	V163Y	Neutral	0.097
OPA1	O60313-1.3	K164A	Neutral	0.109
OPA1	O60313-1.3	K164C	Neutral	0.374
OPA1	O60313-1.3	K164D	Neutral	0.265
OPA1	O60313-1.3	K164E	Neutral	0.039
OPA1	O60313-1.3	K164F	Neutral	0.255
OPA1	O60313-1.3	K164G	Neutral	0.305
OPA1	O60313-1.3	K164H	Neutral	0.149
OPA1	O60313-1.3	K164I	Neutral	0.245
OPA1	O60313-1.3	K164L	Neutral	0.11
OPA1	O60313-1.3	K164M	Neutral	0.061
OPA1	O60313-1.3	K164N	Neutral	0.098
OPA1	O60313-1.3	K164P	Neutral	0.084
OPA1	O60313-1.3	K164Q	Neutral	0.027
OPA1	O60313-1.3	K164R	Neutral	0.02
OPA1	O60313-1.3	K164S	Neutral	0.056
OPA1	O60313-1.3	K164T	Neutral	0.124
OPA1	O60313-1.3	K164V	Neutral	0.151
OPA1	O60313-1.3	K164W	Neutral	0.168
OPA1	O60313-1.3	K164Y	Neutral	0.198
OPA1	O60313-1.3	L165A	Neutral	0.085
OPA1	O60313-1.3	L165C	Neutral	0.157
OPA1	O60313-1.3	L165D	Neutral	0.481
OPA1	O60313-1.3	L165E	Neutral	0.278
OPA1	O60313-1.3	L165F	Neutral	0.112
OPA1	O60313-1.3	L165G	Pathogenic	0.615
OPA1	O60313-1.3	L165H	Neutral	0.447
OPA1	O60313-1.3	L165I	Neutral	0.015
OPA1	O60313-1.3	L165K	Neutral	0.089
OPA1	O60313-1.3	L165M	Neutral	0.011
OPA1	O60313-1.3	L165N	Neutral	0.275
OPA1	O60313-1.3	L165P	Pathogenic	0.554
OPA1	O60313-1.3	L165Q	Neutral	0.166
OPA1	O60313-1.3	L165R	Neutral	0.084
OPA1	O60313-1.3	L165S	Neutral	0.168
OPA1	O60313-1.3	L165T	Neutral	0.089
OPA1	O60313-1.3	L165V	Neutral	0.029
OPA1	O60313-1.3	L165W	Neutral	0.385
OPA1	O60313-1.3	L165Y	Neutral	0.164
OPA1	O60313-1.3	A166C	Neutral	0.004
OPA1	O60313-1.3	A166D	Neutral	0.02
OPA1	O60313-1.3	A166E	Neutral	0.007
OPA1	O60313-1.3	A166F	Neutral	0.012
OPA1	O60313-1.3	A166G	Neutral	0.005
OPA1	O60313-1.3	A166H	Neutral	0.041
OPA1	O60313-1.3	A166I	Neutral	0.004
OPA1	O60313-1.3	A166K	Neutral	0.005
OPA1	O60313-1.3	A166L	Neutral	0.005
OPA1	O60313-1.3	A166M	Neutral	0.007
OPA1	O60313-1.3	A166N	Neutral	0.023
OPA1	O60313-1.3	A166P	Neutral	0.013
OPA1	O60313-1.3	A166Q	Neutral	0.011
OPA1	O60313-1.3	A166R	Neutral	0.005
OPA1	O60313-1.3	A166S	Neutral	0.002
OPA1	O60313-1.3	A166T	Neutral	0.006
OPA1	O60313-1.3	A166V	Neutral	0.003
OPA1	O60313-1.3	A166W	Neutral	0.02
OPA1	O60313-1.3	A166Y	Neutral	0.025
OPA1	O60313-1.3	P167A	Pathogenic	0.879
OPA1	O60313-1.3	P167C	Pathogenic	0.987
OPA1	O60313-1.3	P167D	Pathogenic	0.747
OPA1	O60313-1.3	P167E	Pathogenic	0.757
OPA1	O60313-1.3	P167F	Pathogenic	0.989
OPA1	O60313-1.3	P167G	Pathogenic	0.937
OPA1	O60313-1.3	P167H	Pathogenic	0.946
OPA1	O60313-1.3	P167I	Pathogenic	0.969
OPA1	O60313-1.3	P167K	Pathogenic	0.671
OPA1	O60313-1.3	P167L	Pathogenic	0.972
OPA1	O60313-1.3	P167M	Pathogenic	0.949
OPA1	O60313-1.3	P167N	Pathogenic	0.907
OPA1	O60313-1.3	P167Q	Pathogenic	0.817
OPA1	O60313-1.3	P167R	Pathogenic	0.848
OPA1	O60313-1.3	P167S	Pathogenic	0.844
OPA1	O60313-1.3	P167T	Pathogenic	0.882
OPA1	O60313-1.3	P167V	Pathogenic	0.953
OPA1	O60313-1.3	P167W	Pathogenic	0.981
OPA1	O60313-1.3	P167Y	Pathogenic	0.985
OPA1	O60313-1.3	D168A	Pathogenic	0.628
OPA1	O60313-1.3	D168C	Pathogenic	0.739
OPA1	O60313-1.3	D168E	Neutral	0.055
OPA1	O60313-1.3	D168F	Pathogenic	0.54
OPA1	O60313-1.3	D168G	Neutral	0.419
OPA1	O60313-1.3	D168H	Neutral	0.404
OPA1	O60313-1.3	D168I	Pathogenic	0.547
OPA1	O60313-1.3	D168K	Pathogenic	0.543
OPA1	O60313-1.3	D168L	Pathogenic	0.793
OPA1	O60313-1.3	D168M	Pathogenic	0.671
OPA1	O60313-1.3	D168N	Neutral	0.146
OPA1	O60313-1.3	D168P	Neutral	0.304
OPA1	O60313-1.3	D168Q	Neutral	0.247
OPA1	O60313-1.3	D168R	Pathogenic	0.764
OPA1	O60313-1.3	D168S	Neutral	0.22
OPA1	O60313-1.3	D168T	Neutral	0.399
OPA1	O60313-1.3	D168V	Pathogenic	0.689
OPA1	O60313-1.3	D168W	Pathogenic	0.667
OPA1	O60313-1.3	D168Y	Pathogenic	0.71
OPA1	O60313-1.3	F169A	Neutral	0.06
OPA1	O60313-1.3	F169C	Neutral	0.113
OPA1	O60313-1.3	F169D	Neutral	0.07
OPA1	O60313-1.3	F169E	Neutral	0.084
OPA1	O60313-1.3	F169G	Neutral	0.115
OPA1	O60313-1.3	F169H	Neutral	0.022
OPA1	O60313-1.3	F169I	Neutral	0.035
OPA1	O60313-1.3	F169K	Neutral	0.068
OPA1	O60313-1.3	F169L	Neutral	0.033
OPA1	O60313-1.3	F169M	Neutral	0.021
OPA1	O60313-1.3	F169N	Neutral	0.083
OPA1	O60313-1.3	F169P	Neutral	0.461
OPA1	O60313-1.3	F169Q	Neutral	0.12
OPA1	O60313-1.3	F169R	Neutral	0.064
OPA1	O60313-1.3	F169S	Neutral	0.046
OPA1	O60313-1.3	F169T	Neutral	0.063
OPA1	O60313-1.3	F169V	Neutral	0.055
OPA1	O60313-1.3	F169W	Neutral	0.008
OPA1	O60313-1.3	F169Y	Neutral	0.001
OPA1	O60313-1.3	D170A	Neutral	0.176
OPA1	O60313-1.3	D170C	Neutral	0.264
OPA1	O60313-1.3	D170E	Neutral	0.007
OPA1	O60313-1.3	D170F	Neutral	0.129
OPA1	O60313-1.3	D170G	Neutral	0.084
OPA1	O60313-1.3	D170H	Neutral	0.079
OPA1	O60313-1.3	D170I	Neutral	0.132
OPA1	O60313-1.3	D170K	Neutral	0.131
OPA1	O60313-1.3	D170L	Neutral	0.327
OPA1	O60313-1.3	D170M	Neutral	0.205
OPA1	O60313-1.3	D170N	Neutral	0.021
OPA1	O60313-1.3	D170P	Neutral	0.052
OPA1	O60313-1.3	D170Q	Neutral	0.04
OPA1	O60313-1.3	D170R	Neutral	0.29
OPA1	O60313-1.3	D170S	Neutral	0.034
OPA1	O60313-1.3	D170T	Neutral	0.078
OPA1	O60313-1.3	D170V	Neutral	0.219
OPA1	O60313-1.3	D170W	Neutral	0.203
OPA1	O60313-1.3	D170Y	Neutral	0.237
OPA1	O60313-1.3	K171A	Neutral	0.217
OPA1	O60313-1.3	K171C	Pathogenic	0.575
OPA1	O60313-1.3	K171D	Neutral	0.449
OPA1	O60313-1.3	K171E	Neutral	0.084
OPA1	O60313-1.3	K171F	Neutral	0.437
OPA1	O60313-1.3	K171G	Neutral	0.499
OPA1	O60313-1.3	K171H	Neutral	0.283
OPA1	O60313-1.3	K171I	Neutral	0.424
OPA1	O60313-1.3	K171L	Neutral	0.218
OPA1	O60313-1.3	K171M	Neutral	0.129
OPA1	O60313-1.3	K171N	Neutral	0.197
OPA1	O60313-1.3	K171P	Neutral	0.172
OPA1	O60313-1.3	K171Q	Neutral	0.06
OPA1	O60313-1.3	K171R	Neutral	0.043
OPA1	O60313-1.3	K171S	Neutral	0.118
OPA1	O60313-1.3	K171T	Neutral	0.243
OPA1	O60313-1.3	K171V	Neutral	0.288
OPA1	O60313-1.3	K171W	Neutral	0.314
OPA1	O60313-1.3	K171Y	Neutral	0.359
OPA1	O60313-1.3	I172A	Neutral	0.096
OPA1	O60313-1.3	I172C	Neutral	0.174
OPA1	O60313-1.3	I172D	Neutral	0.267
OPA1	O60313-1.3	I172E	Neutral	0.305
OPA1	O60313-1.3	I172F	Neutral	0.144
OPA1	O60313-1.3	I172G	Pathogenic	0.645
OPA1	O60313-1.3	I172H	Neutral	0.479
OPA1	O60313-1.3	I172K	Neutral	0.244
OPA1	O60313-1.3	I172L	Neutral	0.019
OPA1	O60313-1.3	I172M	Neutral	0.035
OPA1	O60313-1.3	I172N	Neutral	0.302
OPA1	O60313-1.3	I172P	Pathogenic	0.586
OPA1	O60313-1.3	I172Q	Neutral	0.396
OPA1	O60313-1.3	I172R	Neutral	0.233
OPA1	O60313-1.3	I172S	Neutral	0.187
OPA1	O60313-1.3	I172T	Neutral	0.1
OPA1	O60313-1.3	I172V	Neutral	0.004
OPA1	O60313-1.3	I172W	Pathogenic	0.713
OPA1	O60313-1.3	I172Y	Neutral	0.183
OPA1	O60313-1.3	V173A	Neutral	0.005
OPA1	O60313-1.3	V173C	Neutral	0.027
OPA1	O60313-1.3	V173D	Neutral	0.045
OPA1	O60313-1.3	V173E	Neutral	0.019
OPA1	O60313-1.3	V173F	Neutral	0.019
OPA1	O60313-1.3	V173G	Neutral	0.076
OPA1	O60313-1.3	V173H	Neutral	0.098
OPA1	O60313-1.3	V173I	Neutral	0.0
OPA1	O60313-1.3	V173K	Neutral	0.012
OPA1	O60313-1.3	V173L	Neutral	0.003
OPA1	O60313-1.3	V173M	Neutral	0.004
OPA1	O60313-1.3	V173N	Neutral	0.053
OPA1	O60313-1.3	V173P	Neutral	0.06
OPA1	O60313-1.3	V173Q	Neutral	0.027
OPA1	O60313-1.3	V173R	Neutral	0.033
OPA1	O60313-1.3	V173S	Neutral	0.029
OPA1	O60313-1.3	V173T	Neutral	0.005
OPA1	O60313-1.3	V173W	Neutral	0.088
OPA1	O60313-1.3	V173Y	Neutral	0.025
OPA1	O60313-1.3	E174A	Neutral	0.246
OPA1	O60313-1.3	E174C	Pathogenic	0.822
OPA1	O60313-1.3	E174D	Neutral	0.03
OPA1	O60313-1.3	E174F	Neutral	0.429
OPA1	O60313-1.3	E174G	Pathogenic	0.539
OPA1	O60313-1.3	E174H	Neutral	0.13
OPA1	O60313-1.3	E174I	Neutral	0.436
OPA1	O60313-1.3	E174K	Neutral	0.066
OPA1	O60313-1.3	E174L	Neutral	0.459
OPA1	O60313-1.3	E174M	Neutral	0.31
OPA1	O60313-1.3	E174N	Neutral	0.224
OPA1	O60313-1.3	E174P	Neutral	0.196
OPA1	O60313-1.3	E174Q	Neutral	0.024
OPA1	O60313-1.3	E174R	Neutral	0.162
OPA1	O60313-1.3	E174S	Neutral	0.136
OPA1	O60313-1.3	E174T	Neutral	0.274
OPA1	O60313-1.3	E174V	Neutral	0.322
OPA1	O60313-1.3	E174W	Neutral	0.307
OPA1	O60313-1.3	E174Y	Neutral	0.351
OPA1	O60313-1.3	S175A	Neutral	0.007
OPA1	O60313-1.3	S175C	Neutral	0.03
OPA1	O60313-1.3	S175D	Neutral	0.014
OPA1	O60313-1.3	S175E	Neutral	0.014
OPA1	O60313-1.3	S175F	Neutral	0.035
OPA1	O60313-1.3	S175G	Neutral	0.025
OPA1	O60313-1.3	S175H	Neutral	0.057
OPA1	O60313-1.3	S175I	Neutral	0.036
OPA1	O60313-1.3	S175K	Neutral	0.009
OPA1	O60313-1.3	S175L	Neutral	0.039
OPA1	O60313-1.3	S175M	Neutral	0.021
OPA1	O60313-1.3	S175N	Neutral	0.005
OPA1	O60313-1.3	S175P	Neutral	0.038
OPA1	O60313-1.3	S175Q	Neutral	0.021
OPA1	O60313-1.3	S175R	Neutral	0.025
OPA1	O60313-1.3	S175T	Neutral	0.007
OPA1	O60313-1.3	S175V	Neutral	0.064
OPA1	O60313-1.3	S175W	Neutral	0.058
OPA1	O60313-1.3	S175Y	Neutral	0.07
OPA1	O60313-1.3	L176A	Neutral	0.02
OPA1	O60313-1.3	L176C	Neutral	0.039
OPA1	O60313-1.3	L176D	Neutral	0.167
OPA1	O60313-1.3	L176E	Neutral	0.077
OPA1	O60313-1.3	L176F	Neutral	0.027
OPA1	O60313-1.3	L176G	Neutral	0.257
OPA1	O60313-1.3	L176H	Neutral	0.149
OPA1	O60313-1.3	L176I	Neutral	0.003
OPA1	O60313-1.3	L176K	Neutral	0.021
OPA1	O60313-1.3	L176M	Neutral	0.002
OPA1	O60313-1.3	L176N	Neutral	0.076
OPA1	O60313-1.3	L176P	Neutral	0.212
OPA1	O60313-1.3	L176Q	Neutral	0.041
OPA1	O60313-1.3	L176R	Neutral	0.02
OPA1	O60313-1.3	L176S	Neutral	0.042
OPA1	O60313-1.3	L176T	Neutral	0.021
OPA1	O60313-1.3	L176V	Neutral	0.006
OPA1	O60313-1.3	L176W	Neutral	0.119
OPA1	O60313-1.3	L176Y	Neutral	0.041
OPA1	O60313-1.3	S177A	Neutral	0.001
OPA1	O60313-1.3	S177C	Neutral	0.004
OPA1	O60313-1.3	S177D	Neutral	0.002
OPA1	O60313-1.3	S177E	Neutral	0.002
OPA1	O60313-1.3	S177F	Neutral	0.005
OPA1	O60313-1.3	S177G	Neutral	0.003
OPA1	O60313-1.3	S177H	Neutral	0.008
OPA1	O60313-1.3	S177I	Neutral	0.005
OPA1	O60313-1.3	S177K	Neutral	0.001
OPA1	O60313-1.3	S177L	Neutral	0.006
OPA1	O60313-1.3	S177M	Neutral	0.003
OPA1	O60313-1.3	S177N	Neutral	0.001
OPA1	O60313-1.3	S177P	Neutral	0.005
OPA1	O60313-1.3	S177Q	Neutral	0.003
OPA1	O60313-1.3	S177R	Neutral	0.004
OPA1	O60313-1.3	S177T	Neutral	0.001
OPA1	O60313-1.3	S177V	Neutral	0.009
OPA1	O60313-1.3	S177W	Neutral	0.008
OPA1	O60313-1.3	S177Y	Neutral	0.01
OPA1	O60313-1.3	L178A	Neutral	0.004
OPA1	O60313-1.3	L178C	Neutral	0.008
OPA1	O60313-1.3	L178D	Neutral	0.037
OPA1	O60313-1.3	L178E	Neutral	0.016
OPA1	O60313-1.3	L178F	Neutral	0.005
OPA1	O60313-1.3	L178G	Neutral	0.062
OPA1	O60313-1.3	L178H	Neutral	0.032
OPA1	O60313-1.3	L178I	Neutral	0.001
OPA1	O60313-1.3	L178K	Neutral	0.004
OPA1	O60313-1.3	L178M	Neutral	0.0
OPA1	O60313-1.3	L178N	Neutral	0.016
OPA1	O60313-1.3	L178P	Neutral	0.049
OPA1	O60313-1.3	L178Q	Neutral	0.008
OPA1	O60313-1.3	L178R	Neutral	0.004
OPA1	O60313-1.3	L178S	Neutral	0.008
OPA1	O60313-1.3	L178T	Neutral	0.004
OPA1	O60313-1.3	L178V	Neutral	0.001
OPA1	O60313-1.3	L178W	Neutral	0.025
OPA1	O60313-1.3	L178Y	Neutral	0.008
OPA1	O60313-1.3	L179A	Neutral	0.124
OPA1	O60313-1.3	L179C	Neutral	0.219
OPA1	O60313-1.3	L179D	Pathogenic	0.584
OPA1	O60313-1.3	L179E	Neutral	0.369
OPA1	O60313-1.3	L179F	Neutral	0.16
OPA1	O60313-1.3	L179G	Pathogenic	0.707
OPA1	O60313-1.3	L179H	Pathogenic	0.55
OPA1	O60313-1.3	L179I	Neutral	0.023
OPA1	O60313-1.3	L179K	Neutral	0.129
OPA1	O60313-1.3	L179M	Neutral	0.016
OPA1	O60313-1.3	L179N	Neutral	0.365
OPA1	O60313-1.3	L179P	Pathogenic	0.653
OPA1	O60313-1.3	L179Q	Neutral	0.231
OPA1	O60313-1.3	L179R	Neutral	0.122
OPA1	O60313-1.3	L179S	Neutral	0.234
OPA1	O60313-1.3	L179T	Neutral	0.129
OPA1	O60313-1.3	L179V	Neutral	0.043
OPA1	O60313-1.3	L179W	Neutral	0.486
OPA1	O60313-1.3	L179Y	Neutral	0.229
OPA1	O60313-1.3	K180A	Neutral	0.363
OPA1	O60313-1.3	K180C	Pathogenic	0.735
OPA1	O60313-1.3	K180D	Pathogenic	0.625
OPA1	O60313-1.3	K180E	Neutral	0.158
OPA1	O60313-1.3	K180F	Pathogenic	0.614
OPA1	O60313-1.3	K180G	Pathogenic	0.671
OPA1	O60313-1.3	K180H	Neutral	0.447
OPA1	O60313-1.3	K180I	Pathogenic	0.601
OPA1	O60313-1.3	K180L	Neutral	0.363
OPA1	O60313-1.3	K180M	Neutral	0.232
OPA1	O60313-1.3	K180N	Neutral	0.335
OPA1	O60313-1.3	K180P	Neutral	0.299
OPA1	O60313-1.3	K180Q	Neutral	0.116
OPA1	O60313-1.3	K180R	Neutral	0.085
OPA1	O60313-1.3	K180S	Neutral	0.216
OPA1	O60313-1.3	K180T	Neutral	0.397
OPA1	O60313-1.3	K180V	Neutral	0.453
OPA1	O60313-1.3	K180W	Neutral	0.484
OPA1	O60313-1.3	K180Y	Pathogenic	0.534
OPA1	O60313-1.3	D181A	Neutral	0.023
OPA1	O60313-1.3	D181C	Neutral	0.037
OPA1	O60313-1.3	D181E	Neutral	0.001
OPA1	O60313-1.3	D181F	Neutral	0.016
OPA1	O60313-1.3	D181G	Neutral	0.01
OPA1	O60313-1.3	D181H	Neutral	0.009
OPA1	O60313-1.3	D181I	Neutral	0.016
OPA1	O60313-1.3	D181K	Neutral	0.016
OPA1	O60313-1.3	D181L	Neutral	0.05
OPA1	O60313-1.3	D181M	Neutral	0.027
OPA1	O60313-1.3	D181N	Neutral	0.002
OPA1	O60313-1.3	D181P	Neutral	0.006
OPA1	O60313-1.3	D181Q	Neutral	0.004
OPA1	O60313-1.3	D181R	Neutral	0.042
OPA1	O60313-1.3	D181S	Neutral	0.004
OPA1	O60313-1.3	D181T	Neutral	0.009
OPA1	O60313-1.3	D181V	Neutral	0.029
OPA1	O60313-1.3	D181W	Neutral	0.027
OPA1	O60313-1.3	D181Y	Neutral	0.032
OPA1	O60313-1.3	F182A	Neutral	0.066
OPA1	O60313-1.3	F182C	Neutral	0.123
OPA1	O60313-1.3	F182D	Neutral	0.077
OPA1	O60313-1.3	F182E	Neutral	0.091
OPA1	O60313-1.3	F182G	Neutral	0.125
OPA1	O60313-1.3	F182H	Neutral	0.024
OPA1	O60313-1.3	F182I	Neutral	0.038
OPA1	O60313-1.3	F182K	Neutral	0.074
OPA1	O60313-1.3	F182L	Neutral	0.036
OPA1	O60313-1.3	F182M	Neutral	0.024
OPA1	O60313-1.3	F182N	Neutral	0.09
OPA1	O60313-1.3	F182P	Neutral	0.484
OPA1	O60313-1.3	F182Q	Neutral	0.13
OPA1	O60313-1.3	F182R	Neutral	0.07
OPA1	O60313-1.3	F182S	Neutral	0.05
OPA1	O60313-1.3	F182T	Neutral	0.069
OPA1	O60313-1.3	F182V	Neutral	0.06
OPA1	O60313-1.3	F182W	Neutral	0.008
OPA1	O60313-1.3	F182Y	Neutral	0.001
OPA1	O60313-1.3	F183A	Neutral	0.486
OPA1	O60313-1.3	F183C	Pathogenic	0.653
OPA1	O60313-1.3	F183D	Pathogenic	0.528
OPA1	O60313-1.3	F183E	Pathogenic	0.574
OPA1	O60313-1.3	F183G	Pathogenic	0.658
OPA1	O60313-1.3	F183H	Neutral	0.251
OPA1	O60313-1.3	F183I	Neutral	0.348
OPA1	O60313-1.3	F183K	Pathogenic	0.519
OPA1	O60313-1.3	F183L	Neutral	0.332
OPA1	O60313-1.3	F183M	Neutral	0.245
OPA1	O60313-1.3	F183N	Pathogenic	0.571
OPA1	O60313-1.3	F183P	Pathogenic	0.927
OPA1	O60313-1.3	F183Q	Pathogenic	0.668
OPA1	O60313-1.3	F183R	Pathogenic	0.503
OPA1	O60313-1.3	F183S	Neutral	0.414
OPA1	O60313-1.3	F183T	Neutral	0.498
OPA1	O60313-1.3	F183V	Neutral	0.463
OPA1	O60313-1.3	F183W	Neutral	0.103
OPA1	O60313-1.3	F183Y	Neutral	0.01
OPA1	O60313-1.3	T184A	Neutral	0.026
OPA1	O60313-1.3	T184C	Neutral	0.043
OPA1	O60313-1.3	T184D	Neutral	0.034
OPA1	O60313-1.3	T184E	Neutral	0.036
OPA1	O60313-1.3	T184F	Neutral	0.052
OPA1	O60313-1.3	T184G	Neutral	0.148
OPA1	O60313-1.3	T184H	Neutral	0.174
OPA1	O60313-1.3	T184I	Neutral	0.019
OPA1	O60313-1.3	T184K	Neutral	0.024
OPA1	O60313-1.3	T184L	Neutral	0.021
OPA1	O60313-1.3	T184M	Neutral	0.032
OPA1	O60313-1.3	T184N	Neutral	0.014
OPA1	O60313-1.3	T184P	Neutral	0.055
OPA1	O60313-1.3	T184Q	Neutral	0.051
OPA1	O60313-1.3	T184R	Neutral	0.022
OPA1	O60313-1.3	T184S	Neutral	0.008
OPA1	O60313-1.3	T184V	Neutral	0.012
OPA1	O60313-1.3	T184W	Neutral	0.031
OPA1	O60313-1.3	T184Y	Neutral	0.102
OPA1	O60313-1.3	S185A	Neutral	0.001
OPA1	O60313-1.3	S185C	Neutral	0.006
OPA1	O60313-1.3	S185D	Neutral	0.002
OPA1	O60313-1.3	S185E	Neutral	0.003
OPA1	O60313-1.3	S185F	Neutral	0.006
OPA1	O60313-1.3	S185G	Neutral	0.005
OPA1	O60313-1.3	S185H	Neutral	0.011
OPA1	O60313-1.3	S185I	Neutral	0.007
OPA1	O60313-1.3	S185K	Neutral	0.002
OPA1	O60313-1.3	S185L	Neutral	0.007
OPA1	O60313-1.3	S185M	Neutral	0.004
OPA1	O60313-1.3	S185N	Neutral	0.001
OPA1	O60313-1.3	S185P	Neutral	0.007
OPA1	O60313-1.3	S185Q	Neutral	0.004
OPA1	O60313-1.3	S185R	Neutral	0.005
OPA1	O60313-1.3	S185T	Neutral	0.001
OPA1	O60313-1.3	S185V	Neutral	0.012
OPA1	O60313-1.3	S185W	Neutral	0.011
OPA1	O60313-1.3	S185Y	Neutral	0.013
OPA1	O60313-1.3	G186A	Neutral	0.049
OPA1	O60313-1.3	G186C	Neutral	0.389
OPA1	O60313-1.3	G186D	Neutral	0.083
OPA1	O60313-1.3	G186E	Neutral	0.217
OPA1	O60313-1.3	G186F	Neutral	0.202
OPA1	O60313-1.3	G186H	Neutral	0.298
OPA1	O60313-1.3	G186I	Neutral	0.431
OPA1	O60313-1.3	G186K	Neutral	0.154
OPA1	O60313-1.3	G186L	Neutral	0.454
OPA1	O60313-1.3	G186M	Neutral	0.306
OPA1	O60313-1.3	G186N	Neutral	0.034
OPA1	O60313-1.3	G186P	Neutral	0.216
OPA1	O60313-1.3	G186Q	Neutral	0.285
OPA1	O60313-1.3	G186R	Neutral	0.146
OPA1	O60313-1.3	G186S	Neutral	0.061
OPA1	O60313-1.3	G186T	Neutral	0.294
OPA1	O60313-1.3	G186V	Neutral	0.324
OPA1	O60313-1.3	G186W	Neutral	0.049
OPA1	O60313-1.3	G186Y	Neutral	0.346
OPA1	O60313-1.3	S187A	Neutral	0.006
OPA1	O60313-1.3	S187C	Neutral	0.028
OPA1	O60313-1.3	S187D	Neutral	0.012
OPA1	O60313-1.3	S187E	Neutral	0.013
OPA1	O60313-1.3	S187F	Neutral	0.032
OPA1	O60313-1.3	S187G	Neutral	0.022
OPA1	O60313-1.3	S187H	Neutral	0.052
OPA1	O60313-1.3	S187I	Neutral	0.033
OPA1	O60313-1.3	S187K	Neutral	0.009
OPA1	O60313-1.3	S187L	Neutral	0.036
OPA1	O60313-1.3	S187M	Neutral	0.019
OPA1	O60313-1.3	S187N	Neutral	0.005
OPA1	O60313-1.3	S187P	Neutral	0.034
OPA1	O60313-1.3	S187Q	Neutral	0.019
OPA1	O60313-1.3	S187R	Neutral	0.023
OPA1	O60313-1.3	S187T	Neutral	0.006
OPA1	O60313-1.3	S187V	Neutral	0.058
OPA1	O60313-1.3	S187W	Neutral	0.053
OPA1	O60313-1.3	S187Y	Neutral	0.064
OPA1	O60313-1.3	P188A	Neutral	0.05
OPA1	O60313-1.3	P188C	Neutral	0.354
OPA1	O60313-1.3	P188D	Neutral	0.021
OPA1	O60313-1.3	P188E	Neutral	0.022
OPA1	O60313-1.3	P188F	Neutral	0.394
OPA1	O60313-1.3	P188G	Neutral	0.097
OPA1	O60313-1.3	P188H	Neutral	0.114
OPA1	O60313-1.3	P188I	Neutral	0.187
OPA1	O60313-1.3	P188K	Neutral	0.015
OPA1	O60313-1.3	P188L	Neutral	0.202
OPA1	O60313-1.3	P188M	Neutral	0.118
OPA1	O60313-1.3	P188N	Neutral	0.066
OPA1	O60313-1.3	P188Q	Neutral	0.032
OPA1	O60313-1.3	P188R	Neutral	0.039
OPA1	O60313-1.3	P188S	Neutral	0.038
OPA1	O60313-1.3	P188T	Neutral	0.052
OPA1	O60313-1.3	P188V	Neutral	0.127
OPA1	O60313-1.3	P188W	Neutral	0.277
OPA1	O60313-1.3	P188Y	Neutral	0.319
OPA1	O60313-1.3	E189A	Neutral	0.042
OPA1	O60313-1.3	E189C	Neutral	0.379
OPA1	O60313-1.3	E189D	Neutral	0.004
OPA1	O60313-1.3	E189F	Neutral	0.091
OPA1	O60313-1.3	E189G	Neutral	0.134
OPA1	O60313-1.3	E189H	Neutral	0.019
OPA1	O60313-1.3	E189I	Neutral	0.093
OPA1	O60313-1.3	E189K	Neutral	0.009
OPA1	O60313-1.3	E189L	Neutral	0.101
OPA1	O60313-1.3	E189M	Neutral	0.056
OPA1	O60313-1.3	E189N	Neutral	0.037
OPA1	O60313-1.3	E189P	Neutral	0.031
OPA1	O60313-1.3	E189Q	Neutral	0.003
OPA1	O60313-1.3	E189R	Neutral	0.025
OPA1	O60313-1.3	E189S	Neutral	0.021
OPA1	O60313-1.3	E189T	Neutral	0.048
OPA1	O60313-1.3	E189V	Neutral	0.059
OPA1	O60313-1.3	E189W	Neutral	0.056
OPA1	O60313-1.3	E189Y	Neutral	0.067
OPA1	O60313-1.3	E190A	Neutral	0.054
OPA1	O60313-1.3	E190C	Neutral	0.444
OPA1	O60313-1.3	E190D	Neutral	0.005
OPA1	O60313-1.3	E190F	Neutral	0.115
OPA1	O60313-1.3	E190G	Neutral	0.169
OPA1	O60313-1.3	E190H	Neutral	0.025
OPA1	O60313-1.3	E190I	Neutral	0.118
OPA1	O60313-1.3	E190K	Neutral	0.012
OPA1	O60313-1.3	E190L	Neutral	0.128
OPA1	O60313-1.3	E190M	Neutral	0.072
OPA1	O60313-1.3	E190N	Neutral	0.048
OPA1	O60313-1.3	E190P	Neutral	0.041
OPA1	O60313-1.3	E190Q	Neutral	0.004
OPA1	O60313-1.3	E190R	Neutral	0.032
OPA1	O60313-1.3	E190S	Neutral	0.027
OPA1	O60313-1.3	E190T	Neutral	0.061
OPA1	O60313-1.3	E190V	Neutral	0.076
OPA1	O60313-1.3	E190W	Neutral	0.071
OPA1	O60313-1.3	E190Y	Neutral	0.086
OPA1	O60313-1.3	T191A	Neutral	0.069
OPA1	O60313-1.3	T191C	Neutral	0.11
OPA1	O60313-1.3	T191D	Neutral	0.088
OPA1	O60313-1.3	T191E	Neutral	0.093
OPA1	O60313-1.3	T191F	Neutral	0.131
OPA1	O60313-1.3	T191G	Neutral	0.324
OPA1	O60313-1.3	T191H	Neutral	0.368
OPA1	O60313-1.3	T191I	Neutral	0.051
OPA1	O60313-1.3	T191K	Neutral	0.063
OPA1	O60313-1.3	T191L	Neutral	0.055
OPA1	O60313-1.3	T191M	Neutral	0.083
OPA1	O60313-1.3	T191N	Neutral	0.037
OPA1	O60313-1.3	T191P	Neutral	0.138
OPA1	O60313-1.3	T191Q	Neutral	0.129
OPA1	O60313-1.3	T191R	Neutral	0.06
OPA1	O60313-1.3	T191S	Neutral	0.02
OPA1	O60313-1.3	T191V	Neutral	0.033
OPA1	O60313-1.3	T191W	Neutral	0.082
OPA1	O60313-1.3	T191Y	Neutral	0.239
OPA1	O60313-1.3	A192C	Neutral	0.046
OPA1	O60313-1.3	A192D	Neutral	0.216
OPA1	O60313-1.3	A192E	Neutral	0.091
OPA1	O60313-1.3	A192F	Neutral	0.139
OPA1	O60313-1.3	A192G	Neutral	0.063
OPA1	O60313-1.3	A192H	Neutral	0.363
OPA1	O60313-1.3	A192I	Neutral	0.054
OPA1	O60313-1.3	A192K	Neutral	0.062
OPA1	O60313-1.3	A192L	Neutral	0.059
OPA1	O60313-1.3	A192M	Neutral	0.088
OPA1	O60313-1.3	A192N	Neutral	0.24
OPA1	O60313-1.3	A192P	Neutral	0.15
OPA1	O60313-1.3	A192Q	Neutral	0.126
OPA1	O60313-1.3	A192R	Neutral	0.058
OPA1	O60313-1.3	A192S	Neutral	0.023
OPA1	O60313-1.3	A192T	Neutral	0.077
OPA1	O60313-1.3	A192V	Neutral	0.035
OPA1	O60313-1.3	A192W	Neutral	0.217
OPA1	O60313-1.3	A192Y	Neutral	0.253
OPA1	O60313-1.3	F193A	Neutral	0.308
OPA1	O60313-1.3	F193C	Neutral	0.47
OPA1	O60313-1.3	F193D	Neutral	0.345
OPA1	O60313-1.3	F193E	Neutral	0.388
OPA1	O60313-1.3	F193G	Neutral	0.475
OPA1	O60313-1.3	F193H	Neutral	0.136
OPA1	O60313-1.3	F193I	Neutral	0.2
OPA1	O60313-1.3	F193K	Neutral	0.336
OPA1	O60313-1.3	F193L	Neutral	0.19
OPA1	O60313-1.3	F193M	Neutral	0.132
OPA1	O60313-1.3	F193N	Neutral	0.385
OPA1	O60313-1.3	F193P	Pathogenic	0.856
OPA1	O60313-1.3	F193Q	Neutral	0.487
OPA1	O60313-1.3	F193R	Neutral	0.323
OPA1	O60313-1.3	F193S	Neutral	0.249
OPA1	O60313-1.3	F193T	Neutral	0.319
OPA1	O60313-1.3	F193V	Neutral	0.289
OPA1	O60313-1.3	F193W	Neutral	0.051
OPA1	O60313-1.3	F193Y	Neutral	0.005
OPA1	O60313-1.3	R194A	Neutral	0.043
OPA1	O60313-1.3	R194C	Neutral	0.179
OPA1	O60313-1.3	R194D	Neutral	0.276
OPA1	O60313-1.3	R194E	Neutral	0.041
OPA1	O60313-1.3	R194F	Neutral	0.111
OPA1	O60313-1.3	R194G	Neutral	0.139
OPA1	O60313-1.3	R194H	Neutral	0.022
OPA1	O60313-1.3	R194I	Neutral	0.106
OPA1	O60313-1.3	R194K	Neutral	0.008
OPA1	O60313-1.3	R194L	Neutral	0.043
OPA1	O60313-1.3	R194M	Neutral	0.023
OPA1	O60313-1.3	R194N	Neutral	0.038
OPA1	O60313-1.3	R194P	Neutral	0.089
OPA1	O60313-1.3	R194Q	Neutral	0.01
OPA1	O60313-1.3	R194S	Neutral	0.059
OPA1	O60313-1.3	R194T	Neutral	0.049
OPA1	O60313-1.3	R194V	Neutral	0.159
OPA1	O60313-1.3	R194W	Neutral	0.075
OPA1	O60313-1.3	R194Y	Neutral	0.086
OPA1	O60313-1.3	A195C	Pathogenic	0.591
OPA1	O60313-1.3	A195D	Pathogenic	0.892
OPA1	O60313-1.3	A195E	Pathogenic	0.75
OPA1	O60313-1.3	A195F	Pathogenic	0.829
OPA1	O60313-1.3	A195G	Pathogenic	0.669
OPA1	O60313-1.3	A195H	Pathogenic	0.945
OPA1	O60313-1.3	A195I	Pathogenic	0.632
OPA1	O60313-1.3	A195K	Pathogenic	0.664
OPA1	O60313-1.3	A195L	Pathogenic	0.653
OPA1	O60313-1.3	A195M	Pathogenic	0.743
OPA1	O60313-1.3	A195N	Pathogenic	0.904
OPA1	O60313-1.3	A195P	Pathogenic	0.84
OPA1	O60313-1.3	A195Q	Pathogenic	0.812
OPA1	O60313-1.3	A195R	Pathogenic	0.65
OPA1	O60313-1.3	A195S	Neutral	0.415
OPA1	O60313-1.3	A195T	Pathogenic	0.714
OPA1	O60313-1.3	A195V	Pathogenic	0.521
OPA1	O60313-1.3	A195W	Pathogenic	0.892
OPA1	O60313-1.3	A195Y	Pathogenic	0.91
OPA1	O60313-1.3	T196A	Neutral	0.154
OPA1	O60313-1.3	T196C	Neutral	0.234
OPA1	O60313-1.3	T196D	Neutral	0.191
OPA1	O60313-1.3	T196E	Neutral	0.202
OPA1	O60313-1.3	T196F	Neutral	0.271
OPA1	O60313-1.3	T196G	Pathogenic	0.541
OPA1	O60313-1.3	T196H	Pathogenic	0.589
OPA1	O60313-1.3	T196I	Neutral	0.116
OPA1	O60313-1.3	T196K	Neutral	0.143
OPA1	O60313-1.3	T196L	Neutral	0.126
OPA1	O60313-1.3	T196M	Neutral	0.182
OPA1	O60313-1.3	T196N	Neutral	0.086
OPA1	O60313-1.3	T196P	Neutral	0.283
OPA1	O60313-1.3	T196Q	Neutral	0.267
OPA1	O60313-1.3	T196R	Neutral	0.135
OPA1	O60313-1.3	T196S	Neutral	0.049
OPA1	O60313-1.3	T196V	Neutral	0.077
OPA1	O60313-1.3	T196W	Neutral	0.18
OPA1	O60313-1.3	T196Y	Neutral	0.436
OPA1	O60313-1.3	D197A	Pathogenic	0.56
OPA1	O60313-1.3	D197C	Pathogenic	0.681
OPA1	O60313-1.3	D197E	Neutral	0.042
OPA1	O60313-1.3	D197F	Neutral	0.469
OPA1	O60313-1.3	D197G	Neutral	0.351
OPA1	O60313-1.3	D197H	Neutral	0.337
OPA1	O60313-1.3	D197I	Neutral	0.475
OPA1	O60313-1.3	D197K	Neutral	0.471
OPA1	O60313-1.3	D197L	Pathogenic	0.743
OPA1	O60313-1.3	D197M	Pathogenic	0.605
OPA1	O60313-1.3	D197N	Neutral	0.114
OPA1	O60313-1.3	D197P	Neutral	0.247
OPA1	O60313-1.3	D197Q	Neutral	0.197
OPA1	O60313-1.3	D197R	Pathogenic	0.709
OPA1	O60313-1.3	D197S	Neutral	0.175
OPA1	O60313-1.3	D197T	Neutral	0.333
OPA1	O60313-1.3	D197V	Pathogenic	0.625
OPA1	O60313-1.3	D197W	Pathogenic	0.601
OPA1	O60313-1.3	D197Y	Pathogenic	0.648
OPA1	O60313-1.3	R198A	Neutral	0.0
OPA1	O60313-1.3	R198C	Neutral	0.001
OPA1	O60313-1.3	R198D	Neutral	0.003
OPA1	O60313-1.3	R198E	Neutral	0.0
OPA1	O60313-1.3	R198F	Neutral	0.001
OPA1	O60313-1.3	R198G	Neutral	0.001
OPA1	O60313-1.3	R198H	Neutral	0.0
OPA1	O60313-1.3	R198I	Neutral	0.001
OPA1	O60313-1.3	R198K	Neutral	0.0
OPA1	O60313-1.3	R198L	Neutral	0.0
OPA1	O60313-1.3	R198M	Neutral	0.0
OPA1	O60313-1.3	R198N	Neutral	0.0
OPA1	O60313-1.3	R198P	Neutral	0.001
OPA1	O60313-1.3	R198Q	Neutral	0.0
OPA1	O60313-1.3	R198S	Neutral	0.0
OPA1	O60313-1.3	R198T	Neutral	0.0
OPA1	O60313-1.3	R198V	Neutral	0.001
OPA1	O60313-1.3	R198W	Neutral	0.001
OPA1	O60313-1.3	R198Y	Neutral	0.001
OPA1	O60313-1.3	G199A	Neutral	0.02
OPA1	O60313-1.3	G199C	Neutral	0.204
OPA1	O60313-1.3	G199D	Neutral	0.035
OPA1	O60313-1.3	G199E	Neutral	0.1
OPA1	O60313-1.3	G199F	Neutral	0.092
OPA1	O60313-1.3	G199H	Neutral	0.146
OPA1	O60313-1.3	G199I	Neutral	0.233
OPA1	O60313-1.3	G199K	Neutral	0.068
OPA1	O60313-1.3	G199L	Neutral	0.25
OPA1	O60313-1.3	G199M	Neutral	0.15
OPA1	O60313-1.3	G199N	Neutral	0.014
OPA1	O60313-1.3	G199P	Neutral	0.1
OPA1	O60313-1.3	G199Q	Neutral	0.138
OPA1	O60313-1.3	G199R	Neutral	0.064
OPA1	O60313-1.3	G199S	Neutral	0.026
OPA1	O60313-1.3	G199T	Neutral	0.143
OPA1	O60313-1.3	G199V	Neutral	0.161
OPA1	O60313-1.3	G199W	Neutral	0.02
OPA1	O60313-1.3	G199Y	Neutral	0.175
OPA1	O60313-1.3	S200A	Neutral	0.001
OPA1	O60313-1.3	S200C	Neutral	0.005
OPA1	O60313-1.3	S200D	Neutral	0.002
OPA1	O60313-1.3	S200E	Neutral	0.002
OPA1	O60313-1.3	S200F	Neutral	0.006
OPA1	O60313-1.3	S200G	Neutral	0.004
OPA1	O60313-1.3	S200H	Neutral	0.01
OPA1	O60313-1.3	S200I	Neutral	0.006
OPA1	O60313-1.3	S200K	Neutral	0.002
OPA1	O60313-1.3	S200L	Neutral	0.007
OPA1	O60313-1.3	S200M	Neutral	0.004
OPA1	O60313-1.3	S200N	Neutral	0.001
OPA1	O60313-1.3	S200P	Neutral	0.007
OPA1	O60313-1.3	S200Q	Neutral	0.004
OPA1	O60313-1.3	S200R	Neutral	0.004
OPA1	O60313-1.3	S200T	Neutral	0.001
OPA1	O60313-1.3	S200V	Neutral	0.012
OPA1	O60313-1.3	S200W	Neutral	0.01
OPA1	O60313-1.3	S200Y	Neutral	0.013
OPA1	O60313-1.3	E201A	Neutral	0.08
OPA1	O60313-1.3	E201C	Pathogenic	0.551
OPA1	O60313-1.3	E201D	Neutral	0.008
OPA1	O60313-1.3	E201F	Neutral	0.167
OPA1	O60313-1.3	E201G	Neutral	0.237
OPA1	O60313-1.3	E201H	Neutral	0.038
OPA1	O60313-1.3	E201I	Neutral	0.171
OPA1	O60313-1.3	E201K	Neutral	0.019
OPA1	O60313-1.3	E201L	Neutral	0.184
OPA1	O60313-1.3	E201M	Neutral	0.107
OPA1	O60313-1.3	E201N	Neutral	0.071
OPA1	O60313-1.3	E201P	Neutral	0.061
OPA1	O60313-1.3	E201Q	Neutral	0.007
OPA1	O60313-1.3	E201R	Neutral	0.049
OPA1	O60313-1.3	E201S	Neutral	0.04
OPA1	O60313-1.3	E201T	Neutral	0.091
OPA1	O60313-1.3	E201V	Neutral	0.112
OPA1	O60313-1.3	E201W	Neutral	0.106
OPA1	O60313-1.3	E201Y	Neutral	0.126
OPA1	O60313-1.3	S202A	Neutral	0.008
OPA1	O60313-1.3	S202C	Neutral	0.034
OPA1	O60313-1.3	S202D	Neutral	0.015
OPA1	O60313-1.3	S202E	Neutral	0.016
OPA1	O60313-1.3	S202F	Neutral	0.039
OPA1	O60313-1.3	S202G	Neutral	0.028
OPA1	O60313-1.3	S202H	Neutral	0.064
OPA1	O60313-1.3	S202I	Neutral	0.041
OPA1	O60313-1.3	S202K	Neutral	0.011
OPA1	O60313-1.3	S202L	Neutral	0.044
OPA1	O60313-1.3	S202M	Neutral	0.024
OPA1	O60313-1.3	S202N	Neutral	0.006
OPA1	O60313-1.3	S202P	Neutral	0.043
OPA1	O60313-1.3	S202Q	Neutral	0.023
OPA1	O60313-1.3	S202R	Neutral	0.029
OPA1	O60313-1.3	S202T	Neutral	0.008
OPA1	O60313-1.3	S202V	Neutral	0.072
OPA1	O60313-1.3	S202W	Neutral	0.066
OPA1	O60313-1.3	S202Y	Neutral	0.079
OPA1	O60313-1.3	D203A	Pathogenic	0.532
OPA1	O60313-1.3	D203C	Pathogenic	0.656
OPA1	O60313-1.3	D203E	Neutral	0.038
OPA1	O60313-1.3	D203F	Neutral	0.441
OPA1	O60313-1.3	D203G	Neutral	0.327
OPA1	O60313-1.3	D203H	Neutral	0.313
OPA1	O60313-1.3	D203I	Neutral	0.448
OPA1	O60313-1.3	D203K	Neutral	0.444
OPA1	O60313-1.3	D203L	Pathogenic	0.721
OPA1	O60313-1.3	D203M	Pathogenic	0.578
OPA1	O60313-1.3	D203N	Neutral	0.103
OPA1	O60313-1.3	D203P	Neutral	0.227
OPA1	O60313-1.3	D203Q	Neutral	0.181
OPA1	O60313-1.3	D203R	Pathogenic	0.685
OPA1	O60313-1.3	D203S	Neutral	0.16
OPA1	O60313-1.3	D203T	Neutral	0.309
OPA1	O60313-1.3	D203V	Pathogenic	0.599
OPA1	O60313-1.3	D203W	Pathogenic	0.575
OPA1	O60313-1.3	D203Y	Pathogenic	0.622
OPA1	O60313-1.3	K204A	Neutral	0.306
OPA1	O60313-1.3	K204C	Pathogenic	0.682
OPA1	O60313-1.3	K204D	Pathogenic	0.564
OPA1	O60313-1.3	K204E	Neutral	0.127
OPA1	O60313-1.3	K204F	Pathogenic	0.552
OPA1	O60313-1.3	K204G	Pathogenic	0.612
OPA1	O60313-1.3	K204H	Neutral	0.386
OPA1	O60313-1.3	K204I	Pathogenic	0.539
OPA1	O60313-1.3	K204L	Neutral	0.307
OPA1	O60313-1.3	K204M	Neutral	0.19
OPA1	O60313-1.3	K204N	Neutral	0.281
OPA1	O60313-1.3	K204P	Neutral	0.248
OPA1	O60313-1.3	K204Q	Neutral	0.092
OPA1	O60313-1.3	K204R	Neutral	0.067
OPA1	O60313-1.3	K204S	Neutral	0.176
OPA1	O60313-1.3	K204T	Neutral	0.338
OPA1	O60313-1.3	K204V	Neutral	0.391
OPA1	O60313-1.3	K204W	Neutral	0.421
OPA1	O60313-1.3	K204Y	Neutral	0.47
OPA1	O60313-1.3	H205A	Neutral	0.08
OPA1	O60313-1.3	H205C	Neutral	0.128
OPA1	O60313-1.3	H205D	Neutral	0.017
OPA1	O60313-1.3	H205E	Neutral	0.007
OPA1	O60313-1.3	H205F	Neutral	0.009
OPA1	O60313-1.3	H205G	Neutral	0.078
OPA1	O60313-1.3	H205I	Neutral	0.071
OPA1	O60313-1.3	H205K	Neutral	0.014
OPA1	O60313-1.3	H205L	Neutral	0.077
OPA1	O60313-1.3	H205M	Neutral	0.043
OPA1	O60313-1.3	H205N	Neutral	0.002
OPA1	O60313-1.3	H205P	Neutral	0.061
OPA1	O60313-1.3	H205Q	Neutral	0.01
OPA1	O60313-1.3	H205R	Neutral	0.005
OPA1	O60313-1.3	H205S	Neutral	0.03
OPA1	O60313-1.3	H205T	Neutral	0.092
OPA1	O60313-1.3	H205V	Neutral	0.113
OPA1	O60313-1.3	H205W	Neutral	0.015
OPA1	O60313-1.3	H205Y	Neutral	0.001
OPA1	O60313-1.3	F206A	Neutral	0.064
OPA1	O60313-1.3	F206C	Neutral	0.12
OPA1	O60313-1.3	F206D	Neutral	0.075
OPA1	O60313-1.3	F206E	Neutral	0.089
OPA1	O60313-1.3	F206G	Neutral	0.122
OPA1	O60313-1.3	F206H	Neutral	0.024
OPA1	O60313-1.3	F206I	Neutral	0.037
OPA1	O60313-1.3	F206K	Neutral	0.072
OPA1	O60313-1.3	F206L	Neutral	0.035
OPA1	O60313-1.3	F206M	Neutral	0.023
OPA1	O60313-1.3	F206N	Neutral	0.088
OPA1	O60313-1.3	F206P	Neutral	0.476
OPA1	O60313-1.3	F206Q	Neutral	0.127
OPA1	O60313-1.3	F206R	Neutral	0.068
OPA1	O60313-1.3	F206S	Neutral	0.048
OPA1	O60313-1.3	F206T	Neutral	0.067
OPA1	O60313-1.3	F206V	Neutral	0.059
OPA1	O60313-1.3	F206W	Neutral	0.008
OPA1	O60313-1.3	F206Y	Neutral	0.001
OPA1	O60313-1.3	R207A	Neutral	0.165
OPA1	O60313-1.3	R207C	Neutral	0.49
OPA1	O60313-1.3	R207D	Pathogenic	0.627
OPA1	O60313-1.3	R207E	Neutral	0.159
OPA1	O60313-1.3	R207F	Neutral	0.356
OPA1	O60313-1.3	R207G	Neutral	0.414
OPA1	O60313-1.3	R207H	Neutral	0.088
OPA1	O60313-1.3	R207I	Neutral	0.343
OPA1	O60313-1.3	R207K	Neutral	0.033
OPA1	O60313-1.3	R207L	Neutral	0.165
OPA1	O60313-1.3	R207M	Neutral	0.095
OPA1	O60313-1.3	R207N	Neutral	0.149
OPA1	O60313-1.3	R207P	Neutral	0.3
OPA1	O60313-1.3	R207Q	Neutral	0.043
OPA1	O60313-1.3	R207S	Neutral	0.217
OPA1	O60313-1.3	R207T	Neutral	0.186
OPA1	O60313-1.3	R207V	Neutral	0.454
OPA1	O60313-1.3	R207W	Neutral	0.264
OPA1	O60313-1.3	R207Y	Neutral	0.294
OPA1	O60313-1.3	K208A	Pathogenic	0.523
OPA1	O60313-1.3	K208C	Pathogenic	0.842
OPA1	O60313-1.3	K208D	Pathogenic	0.763
OPA1	O60313-1.3	K208E	Neutral	0.266
OPA1	O60313-1.3	K208F	Pathogenic	0.754
OPA1	O60313-1.3	K208G	Pathogenic	0.797
OPA1	O60313-1.3	K208H	Pathogenic	0.609
OPA1	O60313-1.3	K208I	Pathogenic	0.744
OPA1	O60313-1.3	K208L	Pathogenic	0.524
OPA1	O60313-1.3	K208M	Neutral	0.368
OPA1	O60313-1.3	K208N	Neutral	0.492
OPA1	O60313-1.3	K208P	Neutral	0.451
OPA1	O60313-1.3	K208Q	Neutral	0.201
OPA1	O60313-1.3	K208R	Neutral	0.152
OPA1	O60313-1.3	K208S	Neutral	0.347
OPA1	O60313-1.3	K208T	Pathogenic	0.559
OPA1	O60313-1.3	K208V	Pathogenic	0.615
OPA1	O60313-1.3	K208W	Pathogenic	0.644
OPA1	O60313-1.3	K208Y	Pathogenic	0.688
OPA1	O60313-1.3	V209A	Neutral	0.025
OPA1	O60313-1.3	V209C	Neutral	0.131
OPA1	O60313-1.3	V209D	Neutral	0.205
OPA1	O60313-1.3	V209E	Neutral	0.095
OPA1	O60313-1.3	V209F	Neutral	0.096
OPA1	O60313-1.3	V209G	Neutral	0.308
OPA1	O60313-1.3	V209H	Neutral	0.372
OPA1	O60313-1.3	V209I	Neutral	0.002
OPA1	O60313-1.3	V209K	Neutral	0.064
OPA1	O60313-1.3	V209L	Neutral	0.014
OPA1	O60313-1.3	V209M	Neutral	0.021
OPA1	O60313-1.3	V209N	Neutral	0.235
OPA1	O60313-1.3	V209P	Neutral	0.258
OPA1	O60313-1.3	V209Q	Neutral	0.131
OPA1	O60313-1.3	V209R	Neutral	0.158
OPA1	O60313-1.3	V209S	Neutral	0.14
OPA1	O60313-1.3	V209T	Neutral	0.027
OPA1	O60313-1.3	V209W	Neutral	0.344
OPA1	O60313-1.3	V209Y	Neutral	0.121
OPA1	O60313-1.3	S210A	Neutral	0.293
OPA1	O60313-1.3	S210C	Pathogenic	0.647
OPA1	O60313-1.3	S210D	Neutral	0.446
OPA1	O60313-1.3	S210E	Neutral	0.459
OPA1	O60313-1.3	S210F	Pathogenic	0.679
OPA1	O60313-1.3	S210G	Pathogenic	0.598
OPA1	O60313-1.3	S210H	Pathogenic	0.78
OPA1	O60313-1.3	S210I	Pathogenic	0.685
OPA1	O60313-1.3	S210K	Neutral	0.359
OPA1	O60313-1.3	S210L	Pathogenic	0.705
OPA1	O60313-1.3	S210M	Pathogenic	0.559
OPA1	O60313-1.3	S210N	Neutral	0.241
OPA1	O60313-1.3	S210P	Pathogenic	0.697
OPA1	O60313-1.3	S210Q	Pathogenic	0.55
OPA1	O60313-1.3	S210R	Pathogenic	0.604
OPA1	O60313-1.3	S210T	Neutral	0.292
OPA1	O60313-1.3	S210V	Pathogenic	0.8
OPA1	O60313-1.3	S210W	Pathogenic	0.783
OPA1	O60313-1.3	S210Y	Pathogenic	0.815
OPA1	O60313-1.3	D211A	Pathogenic	0.89
OPA1	O60313-1.3	D211C	Pathogenic	0.931
OPA1	O60313-1.3	D211E	Neutral	0.217
OPA1	O60313-1.3	D211F	Pathogenic	0.848
OPA1	O60313-1.3	D211G	Pathogenic	0.774
OPA1	O60313-1.3	D211H	Pathogenic	0.764
OPA1	O60313-1.3	D211I	Pathogenic	0.852
OPA1	O60313-1.3	D211K	Pathogenic	0.85
OPA1	O60313-1.3	D211L	Pathogenic	0.948
OPA1	O60313-1.3	D211M	Pathogenic	0.907
OPA1	O60313-1.3	D211N	Neutral	0.449
OPA1	O60313-1.3	D211P	Pathogenic	0.675
OPA1	O60313-1.3	D211Q	Pathogenic	0.609
OPA1	O60313-1.3	D211R	Pathogenic	0.939
OPA1	O60313-1.3	D211S	Pathogenic	0.573
OPA1	O60313-1.3	D211T	Pathogenic	0.76
OPA1	O60313-1.3	D211V	Pathogenic	0.913
OPA1	O60313-1.3	D211W	Pathogenic	0.905
OPA1	O60313-1.3	D211Y	Pathogenic	0.921
OPA1	O60313-1.3	K212A	Pathogenic	0.716
OPA1	O60313-1.3	K212C	Pathogenic	0.925
OPA1	O60313-1.3	K212D	Pathogenic	0.881
OPA1	O60313-1.3	K212E	Neutral	0.454
OPA1	O60313-1.3	K212F	Pathogenic	0.876
OPA1	O60313-1.3	K212G	Pathogenic	0.9
OPA1	O60313-1.3	K212H	Pathogenic	0.782
OPA1	O60313-1.3	K212I	Pathogenic	0.869
OPA1	O60313-1.3	K212L	Pathogenic	0.716
OPA1	O60313-1.3	K212M	Pathogenic	0.572
OPA1	O60313-1.3	K212N	Pathogenic	0.69
OPA1	O60313-1.3	K212P	Pathogenic	0.653
OPA1	O60313-1.3	K212Q	Neutral	0.367
OPA1	O60313-1.3	K212R	Neutral	0.291
OPA1	O60313-1.3	K212S	Pathogenic	0.549
OPA1	O60313-1.3	K212T	Pathogenic	0.744
OPA1	O60313-1.3	K212V	Pathogenic	0.785
OPA1	O60313-1.3	K212W	Pathogenic	0.806
OPA1	O60313-1.3	K212Y	Pathogenic	0.835
OPA1	O60313-1.3	E213A	Pathogenic	0.76
OPA1	O60313-1.3	E213C	Pathogenic	0.978
OPA1	O60313-1.3	E213D	Neutral	0.23
OPA1	O60313-1.3	E213F	Pathogenic	0.879
OPA1	O60313-1.3	E213G	Pathogenic	0.919
OPA1	O60313-1.3	E213H	Pathogenic	0.592
OPA1	O60313-1.3	E213I	Pathogenic	0.882
OPA1	O60313-1.3	E213K	Neutral	0.408
OPA1	O60313-1.3	E213L	Pathogenic	0.892
OPA1	O60313-1.3	E213M	Pathogenic	0.813
OPA1	O60313-1.3	E213N	Pathogenic	0.737
OPA1	O60313-1.3	E213P	Pathogenic	0.703
OPA1	O60313-1.3	E213Q	Neutral	0.195
OPA1	O60313-1.3	E213R	Pathogenic	0.652
OPA1	O60313-1.3	E213S	Pathogenic	0.605
OPA1	O60313-1.3	E213T	Pathogenic	0.785
OPA1	O60313-1.3	E213V	Pathogenic	0.822
OPA1	O60313-1.3	E213W	Pathogenic	0.811
OPA1	O60313-1.3	E213Y	Pathogenic	0.84
OPA1	O60313-1.3	K214A	Pathogenic	0.682
OPA1	O60313-1.3	K214C	Pathogenic	0.913
OPA1	O60313-1.3	K214D	Pathogenic	0.863
OPA1	O60313-1.3	K214E	Neutral	0.415
OPA1	O60313-1.3	K214F	Pathogenic	0.857
OPA1	O60313-1.3	K214G	Pathogenic	0.885
OPA1	O60313-1.3	K214H	Pathogenic	0.753
OPA1	O60313-1.3	K214I	Pathogenic	0.85
OPA1	O60313-1.3	K214L	Pathogenic	0.683
OPA1	O60313-1.3	K214M	Pathogenic	0.533
OPA1	O60313-1.3	K214N	Pathogenic	0.655
OPA1	O60313-1.3	K214P	Pathogenic	0.616
OPA1	O60313-1.3	K214Q	Neutral	0.33
OPA1	O60313-1.3	K214R	Neutral	0.259
OPA1	O60313-1.3	K214S	Pathogenic	0.509
OPA1	O60313-1.3	K214T	Pathogenic	0.713
OPA1	O60313-1.3	K214V	Pathogenic	0.757
OPA1	O60313-1.3	K214W	Pathogenic	0.78
OPA1	O60313-1.3	K214Y	Pathogenic	0.812
OPA1	O60313-1.3	I215A	Neutral	0.125
OPA1	O60313-1.3	I215C	Neutral	0.222
OPA1	O60313-1.3	I215D	Neutral	0.329
OPA1	O60313-1.3	I215E	Neutral	0.372
OPA1	O60313-1.3	I215F	Neutral	0.185
OPA1	O60313-1.3	I215G	Pathogenic	0.71
OPA1	O60313-1.3	I215H	Pathogenic	0.553
OPA1	O60313-1.3	I215K	Neutral	0.303
OPA1	O60313-1.3	I215L	Neutral	0.025
OPA1	O60313-1.3	I215M	Neutral	0.047
OPA1	O60313-1.3	I215N	Neutral	0.368
OPA1	O60313-1.3	I215P	Pathogenic	0.656
OPA1	O60313-1.3	I215Q	Neutral	0.469
OPA1	O60313-1.3	I215R	Neutral	0.29
OPA1	O60313-1.3	I215S	Neutral	0.236
OPA1	O60313-1.3	I215T	Neutral	0.131
OPA1	O60313-1.3	I215V	Neutral	0.005
OPA1	O60313-1.3	I215W	Pathogenic	0.77
OPA1	O60313-1.3	I215Y	Neutral	0.232
OPA1	O60313-1.3	D216A	Pathogenic	0.8
OPA1	O60313-1.3	D216C	Pathogenic	0.87
OPA1	O60313-1.3	D216E	Neutral	0.121
OPA1	O60313-1.3	D216F	Pathogenic	0.735
OPA1	O60313-1.3	D216G	Pathogenic	0.63
OPA1	O60313-1.3	D216H	Pathogenic	0.616
OPA1	O60313-1.3	D216I	Pathogenic	0.74
OPA1	O60313-1.3	D216K	Pathogenic	0.737
OPA1	O60313-1.3	D216L	Pathogenic	0.901
OPA1	O60313-1.3	D216M	Pathogenic	0.828
OPA1	O60313-1.3	D216N	Neutral	0.288
OPA1	O60313-1.3	D216P	Pathogenic	0.508
OPA1	O60313-1.3	D216Q	Neutral	0.436
OPA1	O60313-1.3	D216R	Pathogenic	0.884
OPA1	O60313-1.3	D216S	Neutral	0.4
OPA1	O60313-1.3	D216T	Pathogenic	0.611
OPA1	O60313-1.3	D216V	Pathogenic	0.84
OPA1	O60313-1.3	D216W	Pathogenic	0.826
OPA1	O60313-1.3	D216Y	Pathogenic	0.853
OPA1	O60313-1.3	Q217A	Pathogenic	0.808
OPA1	O60313-1.3	Q217C	Pathogenic	0.953
OPA1	O60313-1.3	Q217D	Pathogenic	0.609
OPA1	O60313-1.3	Q217E	Neutral	0.183
OPA1	O60313-1.3	Q217F	Pathogenic	0.909
OPA1	O60313-1.3	Q217G	Pathogenic	0.938
OPA1	O60313-1.3	Q217H	Pathogenic	0.667
OPA1	O60313-1.3	Q217I	Pathogenic	0.912
OPA1	O60313-1.3	Q217K	Neutral	0.307
OPA1	O60313-1.3	Q217L	Pathogenic	0.797
OPA1	O60313-1.3	Q217M	Neutral	0.417
OPA1	O60313-1.3	Q217N	Pathogenic	0.649
OPA1	O60313-1.3	Q217P	Pathogenic	0.759
OPA1	O60313-1.3	Q217R	Neutral	0.294
OPA1	O60313-1.3	Q217S	Pathogenic	0.67
OPA1	O60313-1.3	Q217T	Pathogenic	0.829
OPA1	O60313-1.3	Q217V	Pathogenic	0.86
OPA1	O60313-1.3	Q217W	Pathogenic	0.672
OPA1	O60313-1.3	Q217Y	Pathogenic	0.714
OPA1	O60313-1.3	L218A	Pathogenic	0.875
OPA1	O60313-1.3	L218C	Pathogenic	0.933
OPA1	O60313-1.3	L218D	Pathogenic	0.986
OPA1	O60313-1.3	L218E	Pathogenic	0.967
OPA1	O60313-1.3	L218F	Pathogenic	0.905
OPA1	O60313-1.3	L218G	Pathogenic	0.992
OPA1	O60313-1.3	L218H	Pathogenic	0.984
OPA1	O60313-1.3	L218I	Pathogenic	0.537
OPA1	O60313-1.3	L218K	Pathogenic	0.881
OPA1	O60313-1.3	L218M	Neutral	0.454
OPA1	O60313-1.3	L218N	Pathogenic	0.966
OPA1	O60313-1.3	L218P	Pathogenic	0.989
OPA1	O60313-1.3	L218Q	Pathogenic	0.937
OPA1	O60313-1.3	L218R	Pathogenic	0.874
OPA1	O60313-1.3	L218S	Pathogenic	0.938
OPA1	O60313-1.3	L218T	Pathogenic	0.881
OPA1	O60313-1.3	L218V	Pathogenic	0.689
OPA1	O60313-1.3	L218W	Pathogenic	0.979
OPA1	O60313-1.3	L218Y	Pathogenic	0.937
OPA1	O60313-1.3	Q219A	Pathogenic	0.993
OPA1	O60313-1.3	Q219C	Pathogenic	0.998
OPA1	O60313-1.3	Q219D	Pathogenic	0.98
OPA1	O60313-1.3	Q219E	Pathogenic	0.878
OPA1	O60313-1.3	Q219F	Pathogenic	0.997
OPA1	O60313-1.3	Q219G	Pathogenic	0.998
OPA1	O60313-1.3	Q219H	Pathogenic	0.985
OPA1	O60313-1.3	Q219I	Pathogenic	0.997
OPA1	O60313-1.3	Q219K	Pathogenic	0.934
OPA1	O60313-1.3	Q219L	Pathogenic	0.992
OPA1	O60313-1.3	Q219M	Pathogenic	0.958
OPA1	O60313-1.3	Q219N	Pathogenic	0.983
OPA1	O60313-1.3	Q219P	Pathogenic	0.99
OPA1	O60313-1.3	Q219R	Pathogenic	0.93
OPA1	O60313-1.3	Q219S	Pathogenic	0.985
OPA1	O60313-1.3	Q219T	Pathogenic	0.994
OPA1	O60313-1.3	Q219V	Pathogenic	0.995
OPA1	O60313-1.3	Q219W	Pathogenic	0.985
OPA1	O60313-1.3	Q219Y	Pathogenic	0.988
OPA1	O60313-1.3	E220A	Pathogenic	0.868
OPA1	O60313-1.3	E220C	Pathogenic	0.989
OPA1	O60313-1.3	E220D	Neutral	0.383
OPA1	O60313-1.3	E220F	Pathogenic	0.938
OPA1	O60313-1.3	E220G	Pathogenic	0.959
OPA1	O60313-1.3	E220H	Pathogenic	0.75
OPA1	O60313-1.3	E220I	Pathogenic	0.939
OPA1	O60313-1.3	E220K	Pathogenic	0.588
OPA1	O60313-1.3	E220L	Pathogenic	0.945
OPA1	O60313-1.3	E220M	Pathogenic	0.9
OPA1	O60313-1.3	E220N	Pathogenic	0.853
OPA1	O60313-1.3	E220P	Pathogenic	0.831
OPA1	O60313-1.3	E220Q	Neutral	0.334
OPA1	O60313-1.3	E220R	Pathogenic	0.795
OPA1	O60313-1.3	E220S	Pathogenic	0.76
OPA1	O60313-1.3	E220T	Pathogenic	0.883
OPA1	O60313-1.3	E220V	Pathogenic	0.905
OPA1	O60313-1.3	E220W	Pathogenic	0.899
OPA1	O60313-1.3	E220Y	Pathogenic	0.916
OPA1	O60313-1.3	E221A	Pathogenic	0.99
OPA1	O60313-1.3	E221C	Pathogenic	0.999
OPA1	O60313-1.3	E221D	Pathogenic	0.9
OPA1	O60313-1.3	E221F	Pathogenic	0.995
OPA1	O60313-1.3	E221G	Pathogenic	0.997
OPA1	O60313-1.3	E221H	Pathogenic	0.978
OPA1	O60313-1.3	E221I	Pathogenic	0.996
OPA1	O60313-1.3	E221K	Pathogenic	0.954
OPA1	O60313-1.3	E221L	Pathogenic	0.996
OPA1	O60313-1.3	E221M	Pathogenic	0.992
OPA1	O60313-1.3	E221N	Pathogenic	0.988
OPA1	O60313-1.3	E221P	Pathogenic	0.986
OPA1	O60313-1.3	E221Q	Pathogenic	0.88
OPA1	O60313-1.3	E221R	Pathogenic	0.983
OPA1	O60313-1.3	E221S	Pathogenic	0.979
OPA1	O60313-1.3	E221T	Pathogenic	0.991
OPA1	O60313-1.3	E221V	Pathogenic	0.993
OPA1	O60313-1.3	E221W	Pathogenic	0.992
OPA1	O60313-1.3	E221Y	Pathogenic	0.994
OPA1	O60313-1.3	L222A	Pathogenic	0.874
OPA1	O60313-1.3	L222C	Pathogenic	0.933
OPA1	O60313-1.3	L222D	Pathogenic	0.986
OPA1	O60313-1.3	L222E	Pathogenic	0.966
OPA1	O60313-1.3	L222F	Pathogenic	0.904
OPA1	O60313-1.3	L222G	Pathogenic	0.992
OPA1	O60313-1.3	L222H	Pathogenic	0.984
OPA1	O60313-1.3	L222I	Pathogenic	0.535
OPA1	O60313-1.3	L222K	Pathogenic	0.88
OPA1	O60313-1.3	L222M	Neutral	0.451
OPA1	O60313-1.3	L222N	Pathogenic	0.966
OPA1	O60313-1.3	L222P	Pathogenic	0.989
OPA1	O60313-1.3	L222Q	Pathogenic	0.937
OPA1	O60313-1.3	L222R	Pathogenic	0.873
OPA1	O60313-1.3	L222S	Pathogenic	0.938
OPA1	O60313-1.3	L222T	Pathogenic	0.88
OPA1	O60313-1.3	L222V	Pathogenic	0.687
OPA1	O60313-1.3	L222W	Pathogenic	0.979
OPA1	O60313-1.3	L222Y	Pathogenic	0.936
OPA1	O60313-1.3	L223A	Pathogenic	0.701
OPA1	O60313-1.3	L223C	Pathogenic	0.824
OPA1	O60313-1.3	L223D	Pathogenic	0.959
OPA1	O60313-1.3	L223E	Pathogenic	0.907
OPA1	O60313-1.3	L223F	Pathogenic	0.76
OPA1	O60313-1.3	L223G	Pathogenic	0.976
OPA1	O60313-1.3	L223H	Pathogenic	0.953
OPA1	O60313-1.3	L223I	Neutral	0.279
OPA1	O60313-1.3	L223K	Pathogenic	0.711
OPA1	O60313-1.3	L223M	Neutral	0.217
OPA1	O60313-1.3	L223N	Pathogenic	0.905
OPA1	O60313-1.3	L223P	Pathogenic	0.969
OPA1	O60313-1.3	L223Q	Pathogenic	0.833
OPA1	O60313-1.3	L223R	Pathogenic	0.698
OPA1	O60313-1.3	L223S	Pathogenic	0.835
OPA1	O60313-1.3	L223T	Pathogenic	0.711
OPA1	O60313-1.3	L223V	Neutral	0.425
OPA1	O60313-1.3	L223W	Pathogenic	0.94
OPA1	O60313-1.3	L223Y	Pathogenic	0.832
OPA1	O60313-1.3	H224A	Neutral	0.444
OPA1	O60313-1.3	H224C	Pathogenic	0.573
OPA1	O60313-1.3	H224D	Neutral	0.134
OPA1	O60313-1.3	H224E	Neutral	0.061
OPA1	O60313-1.3	H224F	Neutral	0.075
OPA1	O60313-1.3	H224G	Neutral	0.436
OPA1	O60313-1.3	H224I	Neutral	0.41
OPA1	O60313-1.3	H224K	Neutral	0.116
OPA1	O60313-1.3	H224L	Neutral	0.433
OPA1	O60313-1.3	H224M	Neutral	0.288
OPA1	O60313-1.3	H224N	Neutral	0.021
OPA1	O60313-1.3	H224P	Neutral	0.374
OPA1	O60313-1.3	H224Q	Neutral	0.088
OPA1	O60313-1.3	H224R	Neutral	0.041
OPA1	O60313-1.3	H224S	Neutral	0.221
OPA1	O60313-1.3	H224T	Neutral	0.48
OPA1	O60313-1.3	H224V	Pathogenic	0.537
OPA1	O60313-1.3	H224W	Neutral	0.121
OPA1	O60313-1.3	H224Y	Neutral	0.007
OPA1	O60313-1.3	T225A	Pathogenic	0.716
OPA1	O60313-1.3	T225C	Pathogenic	0.809
OPA1	O60313-1.3	T225D	Pathogenic	0.766
OPA1	O60313-1.3	T225E	Pathogenic	0.778
OPA1	O60313-1.3	T225F	Pathogenic	0.837
OPA1	O60313-1.3	T225G	Pathogenic	0.942
OPA1	O60313-1.3	T225H	Pathogenic	0.952
OPA1	O60313-1.3	T225I	Pathogenic	0.645
OPA1	O60313-1.3	T225K	Pathogenic	0.697
OPA1	O60313-1.3	T225L	Pathogenic	0.667
OPA1	O60313-1.3	T225M	Pathogenic	0.754
OPA1	O60313-1.3	T225N	Pathogenic	0.567
OPA1	O60313-1.3	T225P	Pathogenic	0.845
OPA1	O60313-1.3	T225Q	Pathogenic	0.834
OPA1	O60313-1.3	T225R	Pathogenic	0.684
OPA1	O60313-1.3	T225S	Neutral	0.416
OPA1	O60313-1.3	T225V	Pathogenic	0.536
OPA1	O60313-1.3	T225W	Pathogenic	0.752
OPA1	O60313-1.3	T225Y	Pathogenic	0.915
OPA1	O60313-1.3	Q226A	Pathogenic	0.994
OPA1	O60313-1.3	Q226C	Pathogenic	0.999
OPA1	O60313-1.3	Q226D	Pathogenic	0.984
OPA1	O60313-1.3	Q226E	Pathogenic	0.9
OPA1	O60313-1.3	Q226F	Pathogenic	0.998
OPA1	O60313-1.3	Q226G	Pathogenic	0.998
OPA1	O60313-1.3	Q226H	Pathogenic	0.988
OPA1	O60313-1.3	Q226I	Pathogenic	0.998
OPA1	O60313-1.3	Q226K	Pathogenic	0.947
OPA1	O60313-1.3	Q226L	Pathogenic	0.994
OPA1	O60313-1.3	Q226M	Pathogenic	0.967
OPA1	O60313-1.3	Q226N	Pathogenic	0.987
OPA1	O60313-1.3	Q226P	Pathogenic	0.992
OPA1	O60313-1.3	Q226R	Pathogenic	0.944
OPA1	O60313-1.3	Q226S	Pathogenic	0.988
OPA1	O60313-1.3	Q226T	Pathogenic	0.995
OPA1	O60313-1.3	Q226V	Pathogenic	0.996
OPA1	O60313-1.3	Q226W	Pathogenic	0.988
OPA1	O60313-1.3	Q226Y	Pathogenic	0.99
OPA1	O60313-1.3	L227A	Pathogenic	0.664
OPA1	O60313-1.3	L227C	Pathogenic	0.797
OPA1	O60313-1.3	L227D	Pathogenic	0.951
OPA1	O60313-1.3	L227E	Pathogenic	0.891
OPA1	O60313-1.3	L227F	Pathogenic	0.727
OPA1	O60313-1.3	L227G	Pathogenic	0.971
OPA1	O60313-1.3	L227H	Pathogenic	0.945
OPA1	O60313-1.3	L227I	Neutral	0.246
OPA1	O60313-1.3	L227K	Pathogenic	0.674
OPA1	O60313-1.3	L227M	Neutral	0.189
OPA1	O60313-1.3	L227N	Pathogenic	0.889
OPA1	O60313-1.3	L227P	Pathogenic	0.963
OPA1	O60313-1.3	L227Q	Pathogenic	0.808
OPA1	O60313-1.3	L227R	Pathogenic	0.66
OPA1	O60313-1.3	L227S	Pathogenic	0.81
OPA1	O60313-1.3	L227T	Pathogenic	0.675
OPA1	O60313-1.3	L227V	Neutral	0.383
OPA1	O60313-1.3	L227W	Pathogenic	0.93
OPA1	O60313-1.3	L227Y	Pathogenic	0.806
OPA1	O60313-1.3	K228A	Pathogenic	0.776
OPA1	O60313-1.3	K228C	Pathogenic	0.944
OPA1	O60313-1.3	K228D	Pathogenic	0.91
OPA1	O60313-1.3	K228E	Pathogenic	0.534
OPA1	O60313-1.3	K228F	Pathogenic	0.906
OPA1	O60313-1.3	K228G	Pathogenic	0.925
OPA1	O60313-1.3	K228H	Pathogenic	0.831
OPA1	O60313-1.3	K228I	Pathogenic	0.902
OPA1	O60313-1.3	K228L	Pathogenic	0.776
OPA1	O60313-1.3	K228M	Pathogenic	0.648
OPA1	O60313-1.3	K228N	Pathogenic	0.754
OPA1	O60313-1.3	K228P	Pathogenic	0.722
OPA1	O60313-1.3	K228Q	Neutral	0.443
OPA1	O60313-1.3	K228R	Neutral	0.361
OPA1	O60313-1.3	K228S	Pathogenic	0.626
OPA1	O60313-1.3	K228T	Pathogenic	0.8
OPA1	O60313-1.3	K228V	Pathogenic	0.834
OPA1	O60313-1.3	K228W	Pathogenic	0.851
OPA1	O60313-1.3	K228Y	Pathogenic	0.874
OPA1	O60313-1.3	Y229A	Pathogenic	0.998
OPA1	O60313-1.3	Y229C	Pathogenic	0.999
OPA1	O60313-1.3	Y229D	Pathogenic	0.998
OPA1	O60313-1.3	Y229E	Pathogenic	0.996
OPA1	O60313-1.3	Y229F	Pathogenic	0.742
OPA1	O60313-1.3	Y229G	Pathogenic	0.999
OPA1	O60313-1.3	Y229H	Pathogenic	0.887
OPA1	O60313-1.3	Y229I	Pathogenic	0.995
OPA1	O60313-1.3	Y229K	Pathogenic	0.995
OPA1	O60313-1.3	Y229L	Pathogenic	0.995
OPA1	O60313-1.3	Y229M	Pathogenic	0.997
OPA1	O60313-1.3	Y229N	Pathogenic	0.996
OPA1	O60313-1.3	Y229P	Pathogenic	1.0
OPA1	O60313-1.3	Y229Q	Pathogenic	0.993
OPA1	O60313-1.3	Y229R	Pathogenic	0.995
OPA1	O60313-1.3	Y229S	Pathogenic	0.998
OPA1	O60313-1.3	Y229T	Pathogenic	0.998
OPA1	O60313-1.3	Y229V	Pathogenic	0.997
OPA1	O60313-1.3	Y229W	Pathogenic	0.837
OPA1	O60313-1.3	Q230A	Pathogenic	0.994
OPA1	O60313-1.3	Q230C	Pathogenic	0.999
OPA1	O60313-1.3	Q230D	Pathogenic	0.984
OPA1	O60313-1.3	Q230E	Pathogenic	0.9
OPA1	O60313-1.3	Q230F	Pathogenic	0.998
OPA1	O60313-1.3	Q230G	Pathogenic	0.998
OPA1	O60313-1.3	Q230H	Pathogenic	0.988
OPA1	O60313-1.3	Q230I	Pathogenic	0.998
OPA1	O60313-1.3	Q230K	Pathogenic	0.947
OPA1	O60313-1.3	Q230L	Pathogenic	0.994
OPA1	O60313-1.3	Q230M	Pathogenic	0.967
OPA1	O60313-1.3	Q230N	Pathogenic	0.987
OPA1	O60313-1.3	Q230P	Pathogenic	0.992
OPA1	O60313-1.3	Q230R	Pathogenic	0.944
OPA1	O60313-1.3	Q230S	Pathogenic	0.988
OPA1	O60313-1.3	Q230T	Pathogenic	0.995
OPA1	O60313-1.3	Q230V	Pathogenic	0.996
OPA1	O60313-1.3	Q230W	Pathogenic	0.988
OPA1	O60313-1.3	Q230Y	Pathogenic	0.99
OPA1	O60313-1.3	R231A	Pathogenic	0.945
OPA1	O60313-1.3	R231C	Pathogenic	0.988
OPA1	O60313-1.3	R231D	Pathogenic	0.993
OPA1	O60313-1.3	R231E	Pathogenic	0.943
OPA1	O60313-1.3	R231F	Pathogenic	0.98
OPA1	O60313-1.3	R231G	Pathogenic	0.984
OPA1	O60313-1.3	R231H	Pathogenic	0.894
OPA1	O60313-1.3	R231I	Pathogenic	0.978
OPA1	O60313-1.3	R231K	Pathogenic	0.749
OPA1	O60313-1.3	R231L	Pathogenic	0.945
OPA1	O60313-1.3	R231M	Pathogenic	0.901
OPA1	O60313-1.3	R231N	Pathogenic	0.938
OPA1	O60313-1.3	R231P	Pathogenic	0.974
OPA1	O60313-1.3	R231Q	Pathogenic	0.798
OPA1	O60313-1.3	R231S	Pathogenic	0.96
OPA1	O60313-1.3	R231T	Pathogenic	0.952
OPA1	O60313-1.3	R231V	Pathogenic	0.986
OPA1	O60313-1.3	R231W	Pathogenic	0.969
OPA1	O60313-1.3	R231Y	Pathogenic	0.973
OPA1	O60313-1.3	I232A	Neutral	0.154
OPA1	O60313-1.3	I232C	Neutral	0.265
OPA1	O60313-1.3	I232D	Neutral	0.384
OPA1	O60313-1.3	I232E	Neutral	0.429
OPA1	O60313-1.3	I232F	Neutral	0.224
OPA1	O60313-1.3	I232G	Pathogenic	0.757
OPA1	O60313-1.3	I232H	Pathogenic	0.611
OPA1	O60313-1.3	I232K	Neutral	0.356
OPA1	O60313-1.3	I232L	Neutral	0.032
OPA1	O60313-1.3	I232M	Neutral	0.059
OPA1	O60313-1.3	I232N	Neutral	0.425
OPA1	O60313-1.3	I232P	Pathogenic	0.708
OPA1	O60313-1.3	I232Q	Pathogenic	0.529
OPA1	O60313-1.3	I232R	Neutral	0.342
OPA1	O60313-1.3	I232S	Neutral	0.282
OPA1	O60313-1.3	I232T	Neutral	0.16
OPA1	O60313-1.3	I232V	Neutral	0.007
OPA1	O60313-1.3	I232W	Pathogenic	0.81
OPA1	O60313-1.3	I232Y	Neutral	0.277
OPA1	O60313-1.3	L233A	Pathogenic	0.907
OPA1	O60313-1.3	L233C	Pathogenic	0.951
OPA1	O60313-1.3	L233D	Pathogenic	0.99
OPA1	O60313-1.3	L233E	Pathogenic	0.976
OPA1	O60313-1.3	L233F	Pathogenic	0.93
OPA1	O60313-1.3	L233G	Pathogenic	0.994
OPA1	O60313-1.3	L233H	Pathogenic	0.988
OPA1	O60313-1.3	L233I	Pathogenic	0.618
OPA1	O60313-1.3	L233K	Pathogenic	0.911
OPA1	O60313-1.3	L233M	Pathogenic	0.536
OPA1	O60313-1.3	L233N	Pathogenic	0.975
OPA1	O60313-1.3	L233P	Pathogenic	0.992
OPA1	O60313-1.3	L233Q	Pathogenic	0.954
OPA1	O60313-1.3	L233R	Pathogenic	0.906
OPA1	O60313-1.3	L233S	Pathogenic	0.955
OPA1	O60313-1.3	L233T	Pathogenic	0.911
OPA1	O60313-1.3	L233V	Pathogenic	0.755
OPA1	O60313-1.3	L233W	Pathogenic	0.985
OPA1	O60313-1.3	L233Y	Pathogenic	0.954
OPA1	O60313-1.3	E234A	Pathogenic	0.99
OPA1	O60313-1.3	E234C	Pathogenic	0.999
OPA1	O60313-1.3	E234D	Pathogenic	0.9
OPA1	O60313-1.3	E234F	Pathogenic	0.995
OPA1	O60313-1.3	E234G	Pathogenic	0.997
OPA1	O60313-1.3	E234H	Pathogenic	0.978
OPA1	O60313-1.3	E234I	Pathogenic	0.996
OPA1	O60313-1.3	E234K	Pathogenic	0.954
OPA1	O60313-1.3	E234L	Pathogenic	0.996
OPA1	O60313-1.3	E234M	Pathogenic	0.992
OPA1	O60313-1.3	E234N	Pathogenic	0.988
OPA1	O60313-1.3	E234P	Pathogenic	0.986
OPA1	O60313-1.3	E234Q	Pathogenic	0.88
OPA1	O60313-1.3	E234R	Pathogenic	0.983
OPA1	O60313-1.3	E234S	Pathogenic	0.979
OPA1	O60313-1.3	E234T	Pathogenic	0.991
OPA1	O60313-1.3	E234V	Pathogenic	0.993
OPA1	O60313-1.3	E234W	Pathogenic	0.992
OPA1	O60313-1.3	E234Y	Pathogenic	0.994
OPA1	O60313-1.3	R235A	Pathogenic	0.946
OPA1	O60313-1.3	R235C	Pathogenic	0.988
OPA1	O60313-1.3	R235D	Pathogenic	0.993
OPA1	O60313-1.3	R235E	Pathogenic	0.943
OPA1	O60313-1.3	R235F	Pathogenic	0.98
OPA1	O60313-1.3	R235G	Pathogenic	0.984
OPA1	O60313-1.3	R235H	Pathogenic	0.895
OPA1	O60313-1.3	R235I	Pathogenic	0.979
OPA1	O60313-1.3	R235K	Pathogenic	0.751
OPA1	O60313-1.3	R235L	Pathogenic	0.946
OPA1	O60313-1.3	R235M	Pathogenic	0.902
OPA1	O60313-1.3	R235N	Pathogenic	0.939
OPA1	O60313-1.3	R235P	Pathogenic	0.974
OPA1	O60313-1.3	R235Q	Pathogenic	0.8
OPA1	O60313-1.3	R235S	Pathogenic	0.961
OPA1	O60313-1.3	R235T	Pathogenic	0.953
OPA1	O60313-1.3	R235V	Pathogenic	0.987
OPA1	O60313-1.3	R235W	Pathogenic	0.969
OPA1	O60313-1.3	R235Y	Pathogenic	0.973
OPA1	O60313-1.3	L236A	Pathogenic	0.959
OPA1	O60313-1.3	L236C	Pathogenic	0.979
OPA1	O60313-1.3	L236D	Pathogenic	0.996
OPA1	O60313-1.3	L236E	Pathogenic	0.99
OPA1	O60313-1.3	L236F	Pathogenic	0.969
OPA1	O60313-1.3	L236G	Pathogenic	0.998
OPA1	O60313-1.3	L236H	Pathogenic	0.995
OPA1	O60313-1.3	L236I	Pathogenic	0.795
OPA1	O60313-1.3	L236K	Pathogenic	0.961
OPA1	O60313-1.3	L236M	Pathogenic	0.735
OPA1	O60313-1.3	L236N	Pathogenic	0.99
OPA1	O60313-1.3	L236P	Pathogenic	0.997
OPA1	O60313-1.3	L236Q	Pathogenic	0.98
OPA1	O60313-1.3	L236R	Pathogenic	0.958
OPA1	O60313-1.3	L236S	Pathogenic	0.981
OPA1	O60313-1.3	L236T	Pathogenic	0.961
OPA1	O60313-1.3	L236V	Pathogenic	0.881
OPA1	O60313-1.3	L236W	Pathogenic	0.994
OPA1	O60313-1.3	L236Y	Pathogenic	0.98
OPA1	O60313-1.3	E237A	Pathogenic	0.99
OPA1	O60313-1.3	E237C	Pathogenic	0.999
OPA1	O60313-1.3	E237D	Pathogenic	0.9
OPA1	O60313-1.3	E237F	Pathogenic	0.995
OPA1	O60313-1.3	E237G	Pathogenic	0.997
OPA1	O60313-1.3	E237H	Pathogenic	0.978
OPA1	O60313-1.3	E237I	Pathogenic	0.996
OPA1	O60313-1.3	E237K	Pathogenic	0.954
OPA1	O60313-1.3	E237L	Pathogenic	0.996
OPA1	O60313-1.3	E237M	Pathogenic	0.992
OPA1	O60313-1.3	E237N	Pathogenic	0.988
OPA1	O60313-1.3	E237P	Pathogenic	0.986
OPA1	O60313-1.3	E237Q	Pathogenic	0.88
OPA1	O60313-1.3	E237R	Pathogenic	0.983
OPA1	O60313-1.3	E237S	Pathogenic	0.979
OPA1	O60313-1.3	E237T	Pathogenic	0.991
OPA1	O60313-1.3	E237V	Pathogenic	0.993
OPA1	O60313-1.3	E237W	Pathogenic	0.992
OPA1	O60313-1.3	E237Y	Pathogenic	0.994
OPA1	O60313-1.3	K238A	Pathogenic	0.847
OPA1	O60313-1.3	K238C	Pathogenic	0.964
OPA1	O60313-1.3	K238D	Pathogenic	0.942
OPA1	O60313-1.3	K238E	Pathogenic	0.646
OPA1	O60313-1.3	K238F	Pathogenic	0.939
OPA1	O60313-1.3	K238G	Pathogenic	0.952
OPA1	O60313-1.3	K238H	Pathogenic	0.887
OPA1	O60313-1.3	K238I	Pathogenic	0.936
OPA1	O60313-1.3	K238L	Pathogenic	0.847
OPA1	O60313-1.3	K238M	Pathogenic	0.746
OPA1	O60313-1.3	K238N	Pathogenic	0.83
OPA1	O60313-1.3	K238P	Pathogenic	0.805
OPA1	O60313-1.3	K238Q	Pathogenic	0.559
OPA1	O60313-1.3	K238R	Neutral	0.474
OPA1	O60313-1.3	K238S	Pathogenic	0.727
OPA1	O60313-1.3	K238T	Pathogenic	0.864
OPA1	O60313-1.3	K238V	Pathogenic	0.889
OPA1	O60313-1.3	K238W	Pathogenic	0.901
OPA1	O60313-1.3	K238Y	Pathogenic	0.917
OPA1	O60313-1.3	E239A	Pathogenic	0.99
OPA1	O60313-1.3	E239C	Pathogenic	0.999
OPA1	O60313-1.3	E239D	Pathogenic	0.9
OPA1	O60313-1.3	E239F	Pathogenic	0.995
OPA1	O60313-1.3	E239G	Pathogenic	0.997
OPA1	O60313-1.3	E239H	Pathogenic	0.978
OPA1	O60313-1.3	E239I	Pathogenic	0.996
OPA1	O60313-1.3	E239K	Pathogenic	0.954
OPA1	O60313-1.3	E239L	Pathogenic	0.996
OPA1	O60313-1.3	E239M	Pathogenic	0.992
OPA1	O60313-1.3	E239N	Pathogenic	0.988
OPA1	O60313-1.3	E239P	Pathogenic	0.986
OPA1	O60313-1.3	E239Q	Pathogenic	0.88
OPA1	O60313-1.3	E239R	Pathogenic	0.983
OPA1	O60313-1.3	E239S	Pathogenic	0.979
OPA1	O60313-1.3	E239T	Pathogenic	0.991
OPA1	O60313-1.3	E239V	Pathogenic	0.993
OPA1	O60313-1.3	E239W	Pathogenic	0.992
OPA1	O60313-1.3	E239Y	Pathogenic	0.994
OPA1	O60313-1.3	N240A	Pathogenic	0.998
OPA1	O60313-1.3	N240C	Pathogenic	0.999
OPA1	O60313-1.3	N240D	Pathogenic	0.974
OPA1	O60313-1.3	N240E	Pathogenic	0.992
OPA1	O60313-1.3	N240F	Pathogenic	0.997
OPA1	O60313-1.3	N240G	Pathogenic	0.984
OPA1	O60313-1.3	N240H	Pathogenic	0.954
OPA1	O60313-1.3	N240I	Pathogenic	0.997
OPA1	O60313-1.3	N240K	Pathogenic	0.987
OPA1	O60313-1.3	N240L	Pathogenic	0.997
OPA1	O60313-1.3	N240M	Pathogenic	0.994
OPA1	O60313-1.3	N240P	Pathogenic	0.997
OPA1	O60313-1.3	N240Q	Pathogenic	0.988
OPA1	O60313-1.3	N240R	Pathogenic	0.986
OPA1	O60313-1.3	N240S	Pathogenic	0.96
OPA1	O60313-1.3	N240T	Pathogenic	0.983
OPA1	O60313-1.3	N240V	Pathogenic	0.998
OPA1	O60313-1.3	N240W	Pathogenic	0.998
OPA1	O60313-1.3	N240Y	Pathogenic	0.995
OPA1	O60313-1.3	K241A	Pathogenic	0.943
OPA1	O60313-1.3	K241C	Pathogenic	0.988
OPA1	O60313-1.3	K241D	Pathogenic	0.98
OPA1	O60313-1.3	K241E	Pathogenic	0.844
OPA1	O60313-1.3	K241F	Pathogenic	0.979
OPA1	O60313-1.3	K241G	Pathogenic	0.983
OPA1	O60313-1.3	K241H	Pathogenic	0.959
OPA1	O60313-1.3	K241I	Pathogenic	0.977
OPA1	O60313-1.3	K241L	Pathogenic	0.943
OPA1	O60313-1.3	K241M	Pathogenic	0.897
OPA1	O60313-1.3	K241N	Pathogenic	0.935
OPA1	O60313-1.3	K241P	Pathogenic	0.925
OPA1	O60313-1.3	K241Q	Pathogenic	0.79
OPA1	O60313-1.3	K241R	Pathogenic	0.728
OPA1	O60313-1.3	K241S	Pathogenic	0.888
OPA1	O60313-1.3	K241T	Pathogenic	0.95
OPA1	O60313-1.3	K241V	Pathogenic	0.96
OPA1	O60313-1.3	K241W	Pathogenic	0.964
OPA1	O60313-1.3	K241Y	Pathogenic	0.971
OPA1	O60313-1.3	E242A	Pathogenic	0.979
OPA1	O60313-1.3	E242C	Pathogenic	0.998
OPA1	O60313-1.3	E242D	Pathogenic	0.814
OPA1	O60313-1.3	E242F	Pathogenic	0.991
OPA1	O60313-1.3	E242G	Pathogenic	0.994
OPA1	O60313-1.3	E242H	Pathogenic	0.955
OPA1	O60313-1.3	E242I	Pathogenic	0.991
OPA1	O60313-1.3	E242K	Pathogenic	0.91
OPA1	O60313-1.3	E242L	Pathogenic	0.992
OPA1	O60313-1.3	E242M	Pathogenic	0.985
OPA1	O60313-1.3	E242N	Pathogenic	0.976
OPA1	O60313-1.3	E242P	Pathogenic	0.972
OPA1	O60313-1.3	E242Q	Pathogenic	0.78
OPA1	O60313-1.3	E242R	Pathogenic	0.965
OPA1	O60313-1.3	E242S	Pathogenic	0.957
OPA1	O60313-1.3	E242T	Pathogenic	0.982
OPA1	O60313-1.3	E242V	Pathogenic	0.985
OPA1	O60313-1.3	E242W	Pathogenic	0.984
OPA1	O60313-1.3	E242Y	Pathogenic	0.987
OPA1	O60313-1.3	L243A	Pathogenic	0.982
OPA1	O60313-1.3	L243C	Pathogenic	0.991
OPA1	O60313-1.3	L243D	Pathogenic	0.998
OPA1	O60313-1.3	L243E	Pathogenic	0.996
OPA1	O60313-1.3	L243F	Pathogenic	0.987
OPA1	O60313-1.3	L243G	Pathogenic	0.999
OPA1	O60313-1.3	L243H	Pathogenic	0.998
OPA1	O60313-1.3	L243I	Pathogenic	0.902
OPA1	O60313-1.3	L243K	Pathogenic	0.983
OPA1	O60313-1.3	L243M	Pathogenic	0.868
OPA1	O60313-1.3	L243N	Pathogenic	0.996
OPA1	O60313-1.3	L243P	Pathogenic	0.999
OPA1	O60313-1.3	L243Q	Pathogenic	0.992
OPA1	O60313-1.3	L243R	Pathogenic	0.982
OPA1	O60313-1.3	L243S	Pathogenic	0.992
OPA1	O60313-1.3	L243T	Pathogenic	0.983
OPA1	O60313-1.3	L243V	Pathogenic	0.946
OPA1	O60313-1.3	L243W	Pathogenic	0.997
OPA1	O60313-1.3	L243Y	Pathogenic	0.992
OPA1	O60313-1.3	R244A	Pathogenic	0.985
OPA1	O60313-1.3	R244C	Pathogenic	0.997
OPA1	O60313-1.3	R244D	Pathogenic	0.998
OPA1	O60313-1.3	R244E	Pathogenic	0.985
OPA1	O60313-1.3	R244F	Pathogenic	0.995
OPA1	O60313-1.3	R244G	Pathogenic	0.996
OPA1	O60313-1.3	R244H	Pathogenic	0.97
OPA1	O60313-1.3	R244I	Pathogenic	0.994
OPA1	O60313-1.3	R244K	Pathogenic	0.921
OPA1	O60313-1.3	R244L	Pathogenic	0.985
OPA1	O60313-1.3	R244M	Pathogenic	0.973
OPA1	O60313-1.3	R244N	Pathogenic	0.983
OPA1	O60313-1.3	R244P	Pathogenic	0.993
OPA1	O60313-1.3	R244Q	Pathogenic	0.939
OPA1	O60313-1.3	R244S	Pathogenic	0.989
OPA1	O60313-1.3	R244T	Pathogenic	0.987
OPA1	O60313-1.3	R244V	Pathogenic	0.996
OPA1	O60313-1.3	R244W	Pathogenic	0.992
OPA1	O60313-1.3	R244Y	Pathogenic	0.993
OPA1	O60313-1.3	K245A	Pathogenic	0.927
OPA1	O60313-1.3	K245C	Pathogenic	0.984
OPA1	O60313-1.3	K245D	Pathogenic	0.974
OPA1	O60313-1.3	K245E	Pathogenic	0.808
OPA1	O60313-1.3	K245F	Pathogenic	0.973
OPA1	O60313-1.3	K245G	Pathogenic	0.979
OPA1	O60313-1.3	K245H	Pathogenic	0.948
OPA1	O60313-1.3	K245I	Pathogenic	0.971
OPA1	O60313-1.3	K245L	Pathogenic	0.927
OPA1	O60313-1.3	K245M	Pathogenic	0.871
OPA1	O60313-1.3	K245N	Pathogenic	0.918
OPA1	O60313-1.3	K245P	Pathogenic	0.905
OPA1	O60313-1.3	K245Q	Pathogenic	0.745
OPA1	O60313-1.3	K245R	Pathogenic	0.675
OPA1	O60313-1.3	K245S	Pathogenic	0.86
OPA1	O60313-1.3	K245T	Pathogenic	0.936
OPA1	O60313-1.3	K245V	Pathogenic	0.949
OPA1	O60313-1.3	K245W	Pathogenic	0.955
OPA1	O60313-1.3	K245Y	Pathogenic	0.962
OPA1	O60313-1.3	L246A	Neutral	0.075
OPA1	O60313-1.3	L246C	Neutral	0.139
OPA1	O60313-1.3	L246D	Neutral	0.445
OPA1	O60313-1.3	L246E	Neutral	0.251
OPA1	O60313-1.3	L246F	Neutral	0.099
OPA1	O60313-1.3	L246G	Pathogenic	0.581
OPA1	O60313-1.3	L246H	Neutral	0.412
OPA1	O60313-1.3	L246I	Neutral	0.013
OPA1	O60313-1.3	L246K	Neutral	0.078
OPA1	O60313-1.3	L246M	Neutral	0.009
OPA1	O60313-1.3	L246N	Neutral	0.248
OPA1	O60313-1.3	L246P	Pathogenic	0.519
OPA1	O60313-1.3	L246Q	Neutral	0.147
OPA1	O60313-1.3	L246R	Neutral	0.074
OPA1	O60313-1.3	L246S	Neutral	0.149
OPA1	O60313-1.3	L246T	Neutral	0.078
OPA1	O60313-1.3	L246V	Neutral	0.025
OPA1	O60313-1.3	L246W	Neutral	0.352
OPA1	O60313-1.3	L246Y	Neutral	0.146
OPA1	O60313-1.3	V247A	Neutral	0.42
OPA1	O60313-1.3	V247C	Pathogenic	0.807
OPA1	O60313-1.3	V247D	Pathogenic	0.878
OPA1	O60313-1.3	V247E	Pathogenic	0.744
OPA1	O60313-1.3	V247F	Pathogenic	0.747
OPA1	O60313-1.3	V247G	Pathogenic	0.925
OPA1	O60313-1.3	V247H	Pathogenic	0.943
OPA1	O60313-1.3	V247I	Neutral	0.041
OPA1	O60313-1.3	V247K	Pathogenic	0.657
OPA1	O60313-1.3	V247L	Neutral	0.284
OPA1	O60313-1.3	V247M	Neutral	0.378
OPA1	O60313-1.3	V247N	Pathogenic	0.895
OPA1	O60313-1.3	V247P	Pathogenic	0.906
OPA1	O60313-1.3	V247Q	Pathogenic	0.807
OPA1	O60313-1.3	V247R	Pathogenic	0.839
OPA1	O60313-1.3	V247S	Pathogenic	0.82
OPA1	O60313-1.3	V247T	Neutral	0.432
OPA1	O60313-1.3	V247W	Pathogenic	0.936
OPA1	O60313-1.3	V247Y	Pathogenic	0.794
OPA1	O60313-1.3	L248A	Pathogenic	0.917
OPA1	O60313-1.3	L248C	Pathogenic	0.957
OPA1	O60313-1.3	L248D	Pathogenic	0.991
OPA1	O60313-1.3	L248E	Pathogenic	0.979
OPA1	O60313-1.3	L248F	Pathogenic	0.938
OPA1	O60313-1.3	L248G	Pathogenic	0.995
OPA1	O60313-1.3	L248H	Pathogenic	0.99
OPA1	O60313-1.3	L248I	Pathogenic	0.648
OPA1	O60313-1.3	L248K	Pathogenic	0.921
OPA1	O60313-1.3	L248M	Pathogenic	0.568
OPA1	O60313-1.3	L248N	Pathogenic	0.978
OPA1	O60313-1.3	L248P	Pathogenic	0.993
OPA1	O60313-1.3	L248Q	Pathogenic	0.96
OPA1	O60313-1.3	L248R	Pathogenic	0.916
OPA1	O60313-1.3	L248S	Pathogenic	0.96
OPA1	O60313-1.3	L248T	Pathogenic	0.921
OPA1	O60313-1.3	L248V	Pathogenic	0.778
OPA1	O60313-1.3	L248W	Pathogenic	0.987
OPA1	O60313-1.3	L248Y	Pathogenic	0.959
OPA1	O60313-1.3	Q249A	Pathogenic	0.918
OPA1	O60313-1.3	Q249C	Pathogenic	0.982
OPA1	O60313-1.3	Q249D	Pathogenic	0.806
OPA1	O60313-1.3	Q249E	Neutral	0.374
OPA1	O60313-1.3	Q249F	Pathogenic	0.964
OPA1	O60313-1.3	Q249G	Pathogenic	0.976
OPA1	O60313-1.3	Q249H	Pathogenic	0.843
OPA1	O60313-1.3	Q249I	Pathogenic	0.965
OPA1	O60313-1.3	Q249K	Pathogenic	0.542
OPA1	O60313-1.3	Q249L	Pathogenic	0.913
OPA1	O60313-1.3	Q249M	Pathogenic	0.657
OPA1	O60313-1.3	Q249N	Pathogenic	0.832
OPA1	O60313-1.3	Q249P	Pathogenic	0.894
OPA1	O60313-1.3	Q249R	Pathogenic	0.527
OPA1	O60313-1.3	Q249S	Pathogenic	0.845
OPA1	O60313-1.3	Q249T	Pathogenic	0.929
OPA1	O60313-1.3	Q249V	Pathogenic	0.942
OPA1	O60313-1.3	Q249W	Pathogenic	0.846
OPA1	O60313-1.3	Q249Y	Pathogenic	0.87
OPA1	O60313-1.3	K250A	Pathogenic	0.638
OPA1	O60313-1.3	K250C	Pathogenic	0.896
OPA1	O60313-1.3	K250D	Pathogenic	0.838
OPA1	O60313-1.3	K250E	Neutral	0.368
OPA1	O60313-1.3	K250F	Pathogenic	0.831
OPA1	O60313-1.3	K250G	Pathogenic	0.863
OPA1	O60313-1.3	K250H	Pathogenic	0.715
OPA1	O60313-1.3	K250I	Pathogenic	0.823
OPA1	O60313-1.3	K250L	Pathogenic	0.638
OPA1	O60313-1.3	K250M	Neutral	0.483
OPA1	O60313-1.3	K250N	Pathogenic	0.609
OPA1	O60313-1.3	K250P	Pathogenic	0.569
OPA1	O60313-1.3	K250Q	Neutral	0.288
OPA1	O60313-1.3	K250R	Neutral	0.223
OPA1	O60313-1.3	K250S	Neutral	0.46
OPA1	O60313-1.3	K250T	Pathogenic	0.671
OPA1	O60313-1.3	K250V	Pathogenic	0.719
OPA1	O60313-1.3	K250W	Pathogenic	0.744
OPA1	O60313-1.3	K250Y	Pathogenic	0.78
OPA1	O60313-1.3	D251A	Pathogenic	0.876
OPA1	O60313-1.3	D251C	Pathogenic	0.922
OPA1	O60313-1.3	D251E	Neutral	0.195
OPA1	O60313-1.3	D251F	Pathogenic	0.83
OPA1	O60313-1.3	D251G	Pathogenic	0.75
OPA1	O60313-1.3	D251H	Pathogenic	0.739
OPA1	O60313-1.3	D251I	Pathogenic	0.834
OPA1	O60313-1.3	D251K	Pathogenic	0.832
OPA1	O60313-1.3	D251L	Pathogenic	0.941
OPA1	O60313-1.3	D251M	Pathogenic	0.895
OPA1	O60313-1.3	D251N	Neutral	0.417
OPA1	O60313-1.3	D251P	Pathogenic	0.646
OPA1	O60313-1.3	D251Q	Pathogenic	0.578
OPA1	O60313-1.3	D251R	Pathogenic	0.931
OPA1	O60313-1.3	D251S	Pathogenic	0.541
OPA1	O60313-1.3	D251T	Pathogenic	0.735
OPA1	O60313-1.3	D251V	Pathogenic	0.902
OPA1	O60313-1.3	D251W	Pathogenic	0.893
OPA1	O60313-1.3	D251Y	Pathogenic	0.911
OPA1	O60313-1.3	D252A	Pathogenic	0.803
OPA1	O60313-1.3	D252C	Pathogenic	0.872
OPA1	O60313-1.3	D252E	Neutral	0.123
OPA1	O60313-1.3	D252F	Pathogenic	0.738
OPA1	O60313-1.3	D252G	Pathogenic	0.634
OPA1	O60313-1.3	D252H	Pathogenic	0.62
OPA1	O60313-1.3	D252I	Pathogenic	0.744
OPA1	O60313-1.3	D252K	Pathogenic	0.741
OPA1	O60313-1.3	D252L	Pathogenic	0.902
OPA1	O60313-1.3	D252M	Pathogenic	0.83
OPA1	O60313-1.3	D252N	Neutral	0.292
OPA1	O60313-1.3	D252P	Pathogenic	0.512
OPA1	O60313-1.3	D252Q	Neutral	0.44
OPA1	O60313-1.3	D252R	Pathogenic	0.886
OPA1	O60313-1.3	D252S	Neutral	0.404
OPA1	O60313-1.3	D252T	Pathogenic	0.615
OPA1	O60313-1.3	D252V	Pathogenic	0.842
OPA1	O60313-1.3	D252W	Pathogenic	0.828
OPA1	O60313-1.3	D252Y	Pathogenic	0.855
OPA1	O60313-1.3	K253A	Pathogenic	0.834
OPA1	O60313-1.3	K253C	Pathogenic	0.961
OPA1	O60313-1.3	K253D	Pathogenic	0.937
OPA1	O60313-1.3	K253E	Pathogenic	0.625
OPA1	O60313-1.3	K253F	Pathogenic	0.934
OPA1	O60313-1.3	K253G	Pathogenic	0.947
OPA1	O60313-1.3	K253H	Pathogenic	0.877
OPA1	O60313-1.3	K253I	Pathogenic	0.93
OPA1	O60313-1.3	K253L	Pathogenic	0.835
OPA1	O60313-1.3	K253M	Pathogenic	0.728
OPA1	O60313-1.3	K253N	Pathogenic	0.816
OPA1	O60313-1.3	K253P	Pathogenic	0.79
OPA1	O60313-1.3	K253Q	Pathogenic	0.537
OPA1	O60313-1.3	K253R	Neutral	0.451
OPA1	O60313-1.3	K253S	Pathogenic	0.709
OPA1	O60313-1.3	K253T	Pathogenic	0.853
OPA1	O60313-1.3	K253V	Pathogenic	0.88
OPA1	O60313-1.3	K253W	Pathogenic	0.892
OPA1	O60313-1.3	K253Y	Pathogenic	0.91
OPA1	O60313-1.3	G254A	Pathogenic	0.886
OPA1	O60313-1.3	G254C	Pathogenic	0.99
OPA1	O60313-1.3	G254D	Pathogenic	0.931
OPA1	O60313-1.3	G254E	Pathogenic	0.976
OPA1	O60313-1.3	G254F	Pathogenic	0.974
OPA1	O60313-1.3	G254H	Pathogenic	0.984
OPA1	O60313-1.3	G254I	Pathogenic	0.991
OPA1	O60313-1.3	G254K	Pathogenic	0.964
OPA1	O60313-1.3	G254L	Pathogenic	0.992
OPA1	O60313-1.3	G254M	Pathogenic	0.985
OPA1	O60313-1.3	G254N	Pathogenic	0.842
OPA1	O60313-1.3	G254P	Pathogenic	0.976
OPA1	O60313-1.3	G254Q	Pathogenic	0.983
OPA1	O60313-1.3	G254R	Pathogenic	0.962
OPA1	O60313-1.3	G254S	Pathogenic	0.907
OPA1	O60313-1.3	G254T	Pathogenic	0.984
OPA1	O60313-1.3	G254V	Pathogenic	0.986
OPA1	O60313-1.3	G254W	Pathogenic	0.885
OPA1	O60313-1.3	G254Y	Pathogenic	0.987
OPA1	O60313-1.3	I255A	Neutral	0.476
OPA1	O60313-1.3	I255C	Pathogenic	0.644
OPA1	O60313-1.3	I255D	Pathogenic	0.757
OPA1	O60313-1.3	I255E	Pathogenic	0.79
OPA1	O60313-1.3	I255F	Pathogenic	0.591
OPA1	O60313-1.3	I255G	Pathogenic	0.94
OPA1	O60313-1.3	I255H	Pathogenic	0.887
OPA1	O60313-1.3	I255K	Pathogenic	0.734
OPA1	O60313-1.3	I255L	Neutral	0.142
OPA1	O60313-1.3	I255M	Neutral	0.237
OPA1	O60313-1.3	I255N	Pathogenic	0.787
OPA1	O60313-1.3	I255P	Pathogenic	0.924
OPA1	O60313-1.3	I255Q	Pathogenic	0.849
OPA1	O60313-1.3	I255R	Pathogenic	0.722
OPA1	O60313-1.3	I255S	Pathogenic	0.663
OPA1	O60313-1.3	I255T	Neutral	0.489
OPA1	O60313-1.3	I255V	Neutral	0.033
OPA1	O60313-1.3	I255W	Pathogenic	0.955
OPA1	O60313-1.3	I255Y	Pathogenic	0.657
OPA1	O60313-1.3	H256A	Pathogenic	0.951
OPA1	O60313-1.3	H256C	Pathogenic	0.97
OPA1	O60313-1.3	H256D	Pathogenic	0.79
OPA1	O60313-1.3	H256E	Pathogenic	0.61
OPA1	O60313-1.3	H256F	Pathogenic	0.662
OPA1	O60313-1.3	H256G	Pathogenic	0.95
OPA1	O60313-1.3	H256I	Pathogenic	0.944
OPA1	O60313-1.3	H256K	Pathogenic	0.762
OPA1	O60313-1.3	H256L	Pathogenic	0.949
OPA1	O60313-1.3	H256M	Pathogenic	0.908
OPA1	O60313-1.3	H256N	Neutral	0.347
OPA1	O60313-1.3	H256P	Pathogenic	0.936
OPA1	O60313-1.3	H256Q	Pathogenic	0.701
OPA1	O60313-1.3	H256R	Pathogenic	0.509
OPA1	O60313-1.3	H256S	Pathogenic	0.873
OPA1	O60313-1.3	H256T	Pathogenic	0.957
OPA1	O60313-1.3	H256V	Pathogenic	0.966
OPA1	O60313-1.3	H256W	Pathogenic	0.77
OPA1	O60313-1.3	H256Y	Neutral	0.144
OPA1	O60313-1.3	H257A	Neutral	0.351
OPA1	O60313-1.3	H257C	Neutral	0.476
OPA1	O60313-1.3	H257D	Neutral	0.095
OPA1	O60313-1.3	H257E	Neutral	0.042
OPA1	O60313-1.3	H257F	Neutral	0.052
OPA1	O60313-1.3	H257G	Neutral	0.344
OPA1	O60313-1.3	H257I	Neutral	0.321
OPA1	O60313-1.3	H257K	Neutral	0.082
OPA1	O60313-1.3	H257L	Neutral	0.342
OPA1	O60313-1.3	H257M	Neutral	0.216
OPA1	O60313-1.3	H257N	Neutral	0.015
OPA1	O60313-1.3	H257P	Neutral	0.288
OPA1	O60313-1.3	H257Q	Neutral	0.061
OPA1	O60313-1.3	H257R	Neutral	0.028
OPA1	O60313-1.3	H257S	Neutral	0.161
OPA1	O60313-1.3	H257T	Neutral	0.385
OPA1	O60313-1.3	H257V	Neutral	0.44
OPA1	O60313-1.3	H257W	Neutral	0.086
OPA1	O60313-1.3	H257Y	Neutral	0.005
OPA1	O60313-1.3	R258A	Pathogenic	0.841
OPA1	O60313-1.3	R258C	Pathogenic	0.962
OPA1	O60313-1.3	R258D	Pathogenic	0.978
OPA1	O60313-1.3	R258E	Pathogenic	0.835
OPA1	O60313-1.3	R258F	Pathogenic	0.936
OPA1	O60313-1.3	R258G	Pathogenic	0.95
OPA1	O60313-1.3	R258H	Pathogenic	0.721
OPA1	O60313-1.3	R258I	Pathogenic	0.933
OPA1	O60313-1.3	R258K	Neutral	0.478
OPA1	O60313-1.3	R258L	Pathogenic	0.841
OPA1	O60313-1.3	R258M	Pathogenic	0.737
OPA1	O60313-1.3	R258N	Pathogenic	0.823
OPA1	O60313-1.3	R258P	Pathogenic	0.92
OPA1	O60313-1.3	R258Q	Pathogenic	0.548
OPA1	O60313-1.3	R258S	Pathogenic	0.881
OPA1	O60313-1.3	R258T	Pathogenic	0.859
OPA1	O60313-1.3	R258V	Pathogenic	0.957
OPA1	O60313-1.3	R258W	Pathogenic	0.905
OPA1	O60313-1.3	R258Y	Pathogenic	0.917
OPA1	O60313-1.3	K259A	Pathogenic	0.963
OPA1	O60313-1.3	K259C	Pathogenic	0.992
OPA1	O60313-1.3	K259D	Pathogenic	0.987
OPA1	O60313-1.3	K259E	Pathogenic	0.896
OPA1	O60313-1.3	K259F	Pathogenic	0.986
OPA1	O60313-1.3	K259G	Pathogenic	0.989
OPA1	O60313-1.3	K259H	Pathogenic	0.974
OPA1	O60313-1.3	K259I	Pathogenic	0.986
OPA1	O60313-1.3	K259L	Pathogenic	0.963
OPA1	O60313-1.3	K259M	Pathogenic	0.932
OPA1	O60313-1.3	K259N	Pathogenic	0.958
OPA1	O60313-1.3	K259P	Pathogenic	0.951
OPA1	O60313-1.3	K259Q	Pathogenic	0.857
OPA1	O60313-1.3	K259R	Pathogenic	0.809
OPA1	O60313-1.3	K259S	Pathogenic	0.926
OPA1	O60313-1.3	K259T	Pathogenic	0.968
OPA1	O60313-1.3	K259V	Pathogenic	0.974
OPA1	O60313-1.3	K259W	Pathogenic	0.977
OPA1	O60313-1.3	K259Y	Pathogenic	0.981
OPA1	O60313-1.3	L260A	Neutral	0.187
OPA1	O60313-1.3	L260C	Neutral	0.314
OPA1	O60313-1.3	L260D	Pathogenic	0.696
OPA1	O60313-1.3	L260E	Neutral	0.488
OPA1	O60313-1.3	L260F	Neutral	0.237
OPA1	O60313-1.3	L260G	Pathogenic	0.798
OPA1	O60313-1.3	L260H	Pathogenic	0.666
OPA1	O60313-1.3	L260I	Neutral	0.037
OPA1	O60313-1.3	L260K	Neutral	0.195
OPA1	O60313-1.3	L260M	Neutral	0.026
OPA1	O60313-1.3	L260N	Neutral	0.484
OPA1	O60313-1.3	L260P	Pathogenic	0.754
OPA1	O60313-1.3	L260Q	Neutral	0.329
OPA1	O60313-1.3	L260R	Neutral	0.185
OPA1	O60313-1.3	L260S	Neutral	0.332
OPA1	O60313-1.3	L260T	Neutral	0.195
OPA1	O60313-1.3	L260V	Neutral	0.068
OPA1	O60313-1.3	L260W	Pathogenic	0.607
OPA1	O60313-1.3	L260Y	Neutral	0.327
OPA1	O60313-1.3	K261A	Pathogenic	0.985
OPA1	O60313-1.3	K261C	Pathogenic	0.997
OPA1	O60313-1.3	K261D	Pathogenic	0.995
OPA1	O60313-1.3	K261E	Pathogenic	0.955
OPA1	O60313-1.3	K261F	Pathogenic	0.994
OPA1	O60313-1.3	K261G	Pathogenic	0.996
OPA1	O60313-1.3	K261H	Pathogenic	0.989
OPA1	O60313-1.3	K261I	Pathogenic	0.994
OPA1	O60313-1.3	K261L	Pathogenic	0.985
OPA1	O60313-1.3	K261M	Pathogenic	0.971
OPA1	O60313-1.3	K261N	Pathogenic	0.983
OPA1	O60313-1.3	K261P	Pathogenic	0.98
OPA1	O60313-1.3	K261Q	Pathogenic	0.936
OPA1	O60313-1.3	K261R	Pathogenic	0.912
OPA1	O60313-1.3	K261S	Pathogenic	0.969
OPA1	O60313-1.3	K261T	Pathogenic	0.987
OPA1	O60313-1.3	K261V	Pathogenic	0.989
OPA1	O60313-1.3	K261W	Pathogenic	0.991
OPA1	O60313-1.3	K261Y	Pathogenic	0.992
OPA1	O60313-1.3	K262A	Pathogenic	0.985
OPA1	O60313-1.3	K262C	Pathogenic	0.997
OPA1	O60313-1.3	K262D	Pathogenic	0.995
OPA1	O60313-1.3	K262E	Pathogenic	0.955
OPA1	O60313-1.3	K262F	Pathogenic	0.994
OPA1	O60313-1.3	K262G	Pathogenic	0.996
OPA1	O60313-1.3	K262H	Pathogenic	0.989
OPA1	O60313-1.3	K262I	Pathogenic	0.994
OPA1	O60313-1.3	K262L	Pathogenic	0.985
OPA1	O60313-1.3	K262M	Pathogenic	0.971
OPA1	O60313-1.3	K262N	Pathogenic	0.983
OPA1	O60313-1.3	K262P	Pathogenic	0.98
OPA1	O60313-1.3	K262Q	Pathogenic	0.936
OPA1	O60313-1.3	K262R	Pathogenic	0.912
OPA1	O60313-1.3	K262S	Pathogenic	0.969
OPA1	O60313-1.3	K262T	Pathogenic	0.987
OPA1	O60313-1.3	K262V	Pathogenic	0.989
OPA1	O60313-1.3	K262W	Pathogenic	0.991
OPA1	O60313-1.3	K262Y	Pathogenic	0.992
OPA1	O60313-1.3	S263A	Pathogenic	0.944
OPA1	O60313-1.3	S263C	Pathogenic	0.987
OPA1	O60313-1.3	S263D	Pathogenic	0.971
OPA1	O60313-1.3	S263E	Pathogenic	0.972
OPA1	O60313-1.3	S263F	Pathogenic	0.989
OPA1	O60313-1.3	S263G	Pathogenic	0.984
OPA1	O60313-1.3	S263H	Pathogenic	0.993
OPA1	O60313-1.3	S263I	Pathogenic	0.989
OPA1	O60313-1.3	S263K	Pathogenic	0.958
OPA1	O60313-1.3	S263L	Pathogenic	0.99
OPA1	O60313-1.3	S263M	Pathogenic	0.981
OPA1	O60313-1.3	S263N	Pathogenic	0.929
OPA1	O60313-1.3	S263P	Pathogenic	0.989
OPA1	O60313-1.3	S263Q	Pathogenic	0.98
OPA1	O60313-1.3	S263R	Pathogenic	0.984
OPA1	O60313-1.3	S263T	Pathogenic	0.944
OPA1	O60313-1.3	S263V	Pathogenic	0.994
OPA1	O60313-1.3	S263W	Pathogenic	0.993
OPA1	O60313-1.3	S263Y	Pathogenic	0.994
OPA1	O60313-1.3	L264A	Pathogenic	0.982
OPA1	O60313-1.3	L264C	Pathogenic	0.991
OPA1	O60313-1.3	L264D	Pathogenic	0.998
OPA1	O60313-1.3	L264E	Pathogenic	0.996
OPA1	O60313-1.3	L264F	Pathogenic	0.987
OPA1	O60313-1.3	L264G	Pathogenic	0.999
OPA1	O60313-1.3	L264H	Pathogenic	0.998
OPA1	O60313-1.3	L264I	Pathogenic	0.902
OPA1	O60313-1.3	L264K	Pathogenic	0.983
OPA1	O60313-1.3	L264M	Pathogenic	0.868
OPA1	O60313-1.3	L264N	Pathogenic	0.996
OPA1	O60313-1.3	L264P	Pathogenic	0.999
OPA1	O60313-1.3	L264Q	Pathogenic	0.992
OPA1	O60313-1.3	L264R	Pathogenic	0.982
OPA1	O60313-1.3	L264S	Pathogenic	0.992
OPA1	O60313-1.3	L264T	Pathogenic	0.983
OPA1	O60313-1.3	L264V	Pathogenic	0.946
OPA1	O60313-1.3	L264W	Pathogenic	0.997
OPA1	O60313-1.3	L264Y	Pathogenic	0.992
OPA1	O60313-1.3	I265A	Pathogenic	0.985
OPA1	O60313-1.3	I265C	Pathogenic	0.993
OPA1	O60313-1.3	I265D	Pathogenic	0.996
OPA1	O60313-1.3	I265E	Pathogenic	0.996
OPA1	O60313-1.3	I265F	Pathogenic	0.991
OPA1	O60313-1.3	I265G	Pathogenic	0.999
OPA1	O60313-1.3	I265H	Pathogenic	0.998
OPA1	O60313-1.3	I265K	Pathogenic	0.995
OPA1	O60313-1.3	I265L	Pathogenic	0.925
OPA1	O60313-1.3	I265M	Pathogenic	0.959
OPA1	O60313-1.3	I265N	Pathogenic	0.996
OPA1	O60313-1.3	I265P	Pathogenic	0.999
OPA1	O60313-1.3	I265Q	Pathogenic	0.998
OPA1	O60313-1.3	I265R	Pathogenic	0.995
OPA1	O60313-1.3	I265S	Pathogenic	0.993
OPA1	O60313-1.3	I265T	Pathogenic	0.986
OPA1	O60313-1.3	I265V	Pathogenic	0.717
OPA1	O60313-1.3	I265W	Pathogenic	0.999
OPA1	O60313-1.3	I265Y	Pathogenic	0.993
OPA1	O60313-1.3	D266A	Pathogenic	0.995
OPA1	O60313-1.3	D266C	Pathogenic	0.997
OPA1	O60313-1.3	D266E	Pathogenic	0.867
OPA1	O60313-1.3	D266F	Pathogenic	0.992
OPA1	O60313-1.3	D266G	Pathogenic	0.988
OPA1	O60313-1.3	D266H	Pathogenic	0.987
OPA1	O60313-1.3	D266I	Pathogenic	0.993
OPA1	O60313-1.3	D266K	Pathogenic	0.993
OPA1	O60313-1.3	D266L	Pathogenic	0.998
OPA1	O60313-1.3	D266M	Pathogenic	0.996
OPA1	O60313-1.3	D266N	Pathogenic	0.95
OPA1	O60313-1.3	D266P	Pathogenic	0.98
OPA1	O60313-1.3	D266Q	Pathogenic	0.973
OPA1	O60313-1.3	D266R	Pathogenic	0.997
OPA1	O60313-1.3	D266S	Pathogenic	0.969
OPA1	O60313-1.3	D266T	Pathogenic	0.987
OPA1	O60313-1.3	D266V	Pathogenic	0.996
OPA1	O60313-1.3	D266W	Pathogenic	0.996
OPA1	O60313-1.3	D266Y	Pathogenic	0.996
OPA1	O60313-1.3	M267A	Pathogenic	0.948
OPA1	O60313-1.3	M267C	Pathogenic	0.973
OPA1	O60313-1.3	M267D	Pathogenic	0.984
OPA1	O60313-1.3	M267E	Pathogenic	0.963
OPA1	O60313-1.3	M267F	Pathogenic	0.913
OPA1	O60313-1.3	M267G	Pathogenic	0.991
OPA1	O60313-1.3	M267H	Pathogenic	0.982
OPA1	O60313-1.3	M267I	Pathogenic	0.788
OPA1	O60313-1.3	M267K	Pathogenic	0.869
OPA1	O60313-1.3	M267L	Pathogenic	0.584
OPA1	O60313-1.3	M267N	Pathogenic	0.962
OPA1	O60313-1.3	M267P	Pathogenic	0.988
OPA1	O60313-1.3	M267Q	Pathogenic	0.822
OPA1	O60313-1.3	M267R	Pathogenic	0.861
OPA1	O60313-1.3	M267S	Pathogenic	0.932
OPA1	O60313-1.3	M267T	Pathogenic	0.95
OPA1	O60313-1.3	M267V	Pathogenic	0.852
OPA1	O60313-1.3	M267W	Pathogenic	0.947
OPA1	O60313-1.3	M267Y	Pathogenic	0.975
OPA1	O60313-1.3	Y268A	Pathogenic	0.998
OPA1	O60313-1.3	Y268C	Pathogenic	0.999
OPA1	O60313-1.3	Y268D	Pathogenic	0.998
OPA1	O60313-1.3	Y268E	Pathogenic	0.996
OPA1	O60313-1.3	Y268F	Pathogenic	0.742
OPA1	O60313-1.3	Y268G	Pathogenic	0.999
OPA1	O60313-1.3	Y268H	Pathogenic	0.887
OPA1	O60313-1.3	Y268I	Pathogenic	0.995
OPA1	O60313-1.3	Y268K	Pathogenic	0.995
OPA1	O60313-1.3	Y268L	Pathogenic	0.995
OPA1	O60313-1.3	Y268M	Pathogenic	0.997
OPA1	O60313-1.3	Y268N	Pathogenic	0.996
OPA1	O60313-1.3	Y268P	Pathogenic	1.0
OPA1	O60313-1.3	Y268Q	Pathogenic	0.993
OPA1	O60313-1.3	Y268R	Pathogenic	0.995
OPA1	O60313-1.3	Y268S	Pathogenic	0.998
OPA1	O60313-1.3	Y268T	Pathogenic	0.998
OPA1	O60313-1.3	Y268V	Pathogenic	0.997
OPA1	O60313-1.3	Y268W	Pathogenic	0.837
OPA1	O60313-1.3	S269A	Pathogenic	0.962
OPA1	O60313-1.3	S269C	Pathogenic	0.991
OPA1	O60313-1.3	S269D	Pathogenic	0.98
OPA1	O60313-1.3	S269E	Pathogenic	0.981
OPA1	O60313-1.3	S269F	Pathogenic	0.992
OPA1	O60313-1.3	S269G	Pathogenic	0.989
OPA1	O60313-1.3	S269H	Pathogenic	0.995
OPA1	O60313-1.3	S269I	Pathogenic	0.993
OPA1	O60313-1.3	S269K	Pathogenic	0.972
OPA1	O60313-1.3	S269L	Pathogenic	0.993
OPA1	O60313-1.3	S269M	Pathogenic	0.987
OPA1	O60313-1.3	S269N	Pathogenic	0.951
OPA1	O60313-1.3	S269P	Pathogenic	0.993
OPA1	O60313-1.3	S269Q	Pathogenic	0.987
OPA1	O60313-1.3	S269R	Pathogenic	0.989
OPA1	O60313-1.3	S269T	Pathogenic	0.962
OPA1	O60313-1.3	S269V	Pathogenic	0.996
OPA1	O60313-1.3	S269W	Pathogenic	0.996
OPA1	O60313-1.3	S269Y	Pathogenic	0.996
OPA1	O60313-1.3	E270A	Pathogenic	0.923
OPA1	O60313-1.3	E270C	Pathogenic	0.994
OPA1	O60313-1.3	E270D	Pathogenic	0.532
OPA1	O60313-1.3	E270F	Pathogenic	0.965
OPA1	O60313-1.3	E270G	Pathogenic	0.977
OPA1	O60313-1.3	E270H	Pathogenic	0.847
OPA1	O60313-1.3	E270I	Pathogenic	0.966
OPA1	O60313-1.3	E270K	Pathogenic	0.724
OPA1	O60313-1.3	E270L	Pathogenic	0.969
OPA1	O60313-1.3	E270M	Pathogenic	0.943
OPA1	O60313-1.3	E270N	Pathogenic	0.914
OPA1	O60313-1.3	E270P	Pathogenic	0.9
OPA1	O60313-1.3	E270Q	Neutral	0.479
OPA1	O60313-1.3	E270R	Pathogenic	0.877
OPA1	O60313-1.3	E270S	Pathogenic	0.853
OPA1	O60313-1.3	E270T	Pathogenic	0.933
OPA1	O60313-1.3	E270V	Pathogenic	0.946
OPA1	O60313-1.3	E270W	Pathogenic	0.942
OPA1	O60313-1.3	E270Y	Pathogenic	0.952
OPA1	O60313-1.3	V271A	Pathogenic	0.975
OPA1	O60313-1.3	V271C	Pathogenic	0.996
OPA1	O60313-1.3	V271D	Pathogenic	0.997
OPA1	O60313-1.3	V271E	Pathogenic	0.994
OPA1	O60313-1.3	V271F	Pathogenic	0.994
OPA1	O60313-1.3	V271G	Pathogenic	0.999
OPA1	O60313-1.3	V271H	Pathogenic	0.999
OPA1	O60313-1.3	V271I	Pathogenic	0.7
OPA1	O60313-1.3	V271K	Pathogenic	0.99
OPA1	O60313-1.3	V271L	Pathogenic	0.956
OPA1	O60313-1.3	V271M	Pathogenic	0.971
OPA1	O60313-1.3	V271N	Pathogenic	0.998
OPA1	O60313-1.3	V271P	Pathogenic	0.998
OPA1	O60313-1.3	V271Q	Pathogenic	0.996
OPA1	O60313-1.3	V271R	Pathogenic	0.996
OPA1	O60313-1.3	V271S	Pathogenic	0.996
OPA1	O60313-1.3	V271T	Pathogenic	0.976
OPA1	O60313-1.3	V271W	Pathogenic	0.999
OPA1	O60313-1.3	V271Y	Pathogenic	0.995
OPA1	O60313-1.3	L272A	Pathogenic	0.982
OPA1	O60313-1.3	L272C	Pathogenic	0.991
OPA1	O60313-1.3	L272D	Pathogenic	0.998
OPA1	O60313-1.3	L272E	Pathogenic	0.996
OPA1	O60313-1.3	L272F	Pathogenic	0.987
OPA1	O60313-1.3	L272G	Pathogenic	0.999
OPA1	O60313-1.3	L272H	Pathogenic	0.998
OPA1	O60313-1.3	L272I	Pathogenic	0.902
OPA1	O60313-1.3	L272K	Pathogenic	0.983
OPA1	O60313-1.3	L272M	Pathogenic	0.868
OPA1	O60313-1.3	L272N	Pathogenic	0.996
OPA1	O60313-1.3	L272P	Pathogenic	0.999
OPA1	O60313-1.3	L272Q	Pathogenic	0.992
OPA1	O60313-1.3	L272R	Pathogenic	0.982
OPA1	O60313-1.3	L272S	Pathogenic	0.992
OPA1	O60313-1.3	L272T	Pathogenic	0.983
OPA1	O60313-1.3	L272V	Pathogenic	0.946
OPA1	O60313-1.3	L272W	Pathogenic	0.997
OPA1	O60313-1.3	L272Y	Pathogenic	0.992
OPA1	O60313-1.3	D273A	Pathogenic	0.997
OPA1	O60313-1.3	D273C	Pathogenic	0.998
OPA1	O60313-1.3	D273E	Pathogenic	0.914
OPA1	O60313-1.3	D273F	Pathogenic	0.995
OPA1	O60313-1.3	D273G	Pathogenic	0.992
OPA1	O60313-1.3	D273H	Pathogenic	0.992
OPA1	O60313-1.3	D273I	Pathogenic	0.995
OPA1	O60313-1.3	D273K	Pathogenic	0.995
OPA1	O60313-1.3	D273L	Pathogenic	0.999
OPA1	O60313-1.3	D273M	Pathogenic	0.997
OPA1	O60313-1.3	D273N	Pathogenic	0.969
OPA1	O60313-1.3	D273P	Pathogenic	0.988
OPA1	O60313-1.3	D273Q	Pathogenic	0.983
OPA1	O60313-1.3	D273R	Pathogenic	0.998
OPA1	O60313-1.3	D273S	Pathogenic	0.981
OPA1	O60313-1.3	D273T	Pathogenic	0.992
OPA1	O60313-1.3	D273V	Pathogenic	0.998
OPA1	O60313-1.3	D273W	Pathogenic	0.997
OPA1	O60313-1.3	D273Y	Pathogenic	0.998
OPA1	O60313-1.3	V274A	Neutral	0.071
OPA1	O60313-1.3	V274C	Neutral	0.307
OPA1	O60313-1.3	V274D	Neutral	0.433
OPA1	O60313-1.3	V274E	Neutral	0.236
OPA1	O60313-1.3	V274F	Neutral	0.238
OPA1	O60313-1.3	V274G	Pathogenic	0.568
OPA1	O60313-1.3	V274H	Pathogenic	0.636
OPA1	O60313-1.3	V274I	Neutral	0.005
OPA1	O60313-1.3	V274K	Neutral	0.169
OPA1	O60313-1.3	V274L	Neutral	0.04
OPA1	O60313-1.3	V274M	Neutral	0.061
OPA1	O60313-1.3	V274N	Neutral	0.476
OPA1	O60313-1.3	V274P	Pathogenic	0.506
OPA1	O60313-1.3	V274Q	Neutral	0.307
OPA1	O60313-1.3	V274R	Neutral	0.356
OPA1	O60313-1.3	V274S	Neutral	0.325
OPA1	O60313-1.3	V274T	Neutral	0.075
OPA1	O60313-1.3	V274W	Pathogenic	0.608
OPA1	O60313-1.3	V274Y	Neutral	0.289
OPA1	O60313-1.3	L275A	Pathogenic	0.982
OPA1	O60313-1.3	L275C	Pathogenic	0.991
OPA1	O60313-1.3	L275D	Pathogenic	0.998
OPA1	O60313-1.3	L275E	Pathogenic	0.996
OPA1	O60313-1.3	L275F	Pathogenic	0.987
OPA1	O60313-1.3	L275G	Pathogenic	0.999
OPA1	O60313-1.3	L275H	Pathogenic	0.998
OPA1	O60313-1.3	L275I	Pathogenic	0.902
OPA1	O60313-1.3	L275K	Pathogenic	0.983
OPA1	O60313-1.3	L275M	Pathogenic	0.868
OPA1	O60313-1.3	L275N	Pathogenic	0.996
OPA1	O60313-1.3	L275P	Pathogenic	0.999
OPA1	O60313-1.3	L275Q	Pathogenic	0.992
OPA1	O60313-1.3	L275R	Pathogenic	0.982
OPA1	O60313-1.3	L275S	Pathogenic	0.992
OPA1	O60313-1.3	L275T	Pathogenic	0.983
OPA1	O60313-1.3	L275V	Pathogenic	0.946
OPA1	O60313-1.3	L275W	Pathogenic	0.997
OPA1	O60313-1.3	L275Y	Pathogenic	0.992
OPA1	O60313-1.3	S276A	Pathogenic	0.882
OPA1	O60313-1.3	S276C	Pathogenic	0.971
OPA1	O60313-1.3	S276D	Pathogenic	0.936
OPA1	O60313-1.3	S276E	Pathogenic	0.939
OPA1	O60313-1.3	S276F	Pathogenic	0.974
OPA1	O60313-1.3	S276G	Pathogenic	0.964
OPA1	O60313-1.3	S276H	Pathogenic	0.985
OPA1	O60313-1.3	S276I	Pathogenic	0.975
OPA1	O60313-1.3	S276K	Pathogenic	0.91
OPA1	O60313-1.3	S276L	Pathogenic	0.977
OPA1	O60313-1.3	S276M	Pathogenic	0.958
OPA1	O60313-1.3	S276N	Pathogenic	0.852
OPA1	O60313-1.3	S276P	Pathogenic	0.976
OPA1	O60313-1.3	S276Q	Pathogenic	0.957
OPA1	O60313-1.3	S276R	Pathogenic	0.965
OPA1	O60313-1.3	S276T	Pathogenic	0.881
OPA1	O60313-1.3	S276V	Pathogenic	0.986
OPA1	O60313-1.3	S276W	Pathogenic	0.985
OPA1	O60313-1.3	S276Y	Pathogenic	0.988
OPA1	O60313-1.3	D277A	Pathogenic	0.992
OPA1	O60313-1.3	D277C	Pathogenic	0.995
OPA1	O60313-1.3	D277E	Pathogenic	0.816
OPA1	O60313-1.3	D277F	Pathogenic	0.989
OPA1	O60313-1.3	D277G	Pathogenic	0.982
OPA1	O60313-1.3	D277H	Pathogenic	0.981
OPA1	O60313-1.3	D277I	Pathogenic	0.989
OPA1	O60313-1.3	D277K	Pathogenic	0.989
OPA1	O60313-1.3	D277L	Pathogenic	0.997
OPA1	O60313-1.3	D277M	Pathogenic	0.994
OPA1	O60313-1.3	D277N	Pathogenic	0.929
OPA1	O60313-1.3	D277P	Pathogenic	0.971
OPA1	O60313-1.3	D277Q	Pathogenic	0.961
OPA1	O60313-1.3	D277R	Pathogenic	0.996
OPA1	O60313-1.3	D277S	Pathogenic	0.956
OPA1	O60313-1.3	D277T	Pathogenic	0.981
OPA1	O60313-1.3	D277V	Pathogenic	0.994
OPA1	O60313-1.3	D277W	Pathogenic	0.993
OPA1	O60313-1.3	D277Y	Pathogenic	0.995
OPA1	O60313-1.3	Y278A	Pathogenic	0.996
OPA1	O60313-1.3	Y278C	Pathogenic	0.998
OPA1	O60313-1.3	Y278D	Pathogenic	0.997
OPA1	O60313-1.3	Y278E	Pathogenic	0.993
OPA1	O60313-1.3	Y278F	Pathogenic	0.602
OPA1	O60313-1.3	Y278G	Pathogenic	0.998
OPA1	O60313-1.3	Y278H	Pathogenic	0.804
OPA1	O60313-1.3	Y278I	Pathogenic	0.99
OPA1	O60313-1.3	Y278K	Pathogenic	0.991
OPA1	O60313-1.3	Y278L	Pathogenic	0.991
OPA1	O60313-1.3	Y278M	Pathogenic	0.994
OPA1	O60313-1.3	Y278N	Pathogenic	0.993
OPA1	O60313-1.3	Y278P	Pathogenic	0.999
OPA1	O60313-1.3	Y278Q	Pathogenic	0.986
OPA1	O60313-1.3	Y278R	Pathogenic	0.991
OPA1	O60313-1.3	Y278S	Pathogenic	0.995
OPA1	O60313-1.3	Y278T	Pathogenic	0.997
OPA1	O60313-1.3	Y278V	Pathogenic	0.994
OPA1	O60313-1.3	Y278W	Pathogenic	0.73
OPA1	O60313-1.3	D279A	Pathogenic	0.997
OPA1	O60313-1.3	D279C	Pathogenic	0.998
OPA1	O60313-1.3	D279E	Pathogenic	0.914
OPA1	O60313-1.3	D279F	Pathogenic	0.995
OPA1	O60313-1.3	D279G	Pathogenic	0.992
OPA1	O60313-1.3	D279H	Pathogenic	0.992
OPA1	O60313-1.3	D279I	Pathogenic	0.995
OPA1	O60313-1.3	D279K	Pathogenic	0.995
OPA1	O60313-1.3	D279L	Pathogenic	0.999
OPA1	O60313-1.3	D279M	Pathogenic	0.997
OPA1	O60313-1.3	D279N	Pathogenic	0.969
OPA1	O60313-1.3	D279P	Pathogenic	0.988
OPA1	O60313-1.3	D279Q	Pathogenic	0.983
OPA1	O60313-1.3	D279R	Pathogenic	0.998
OPA1	O60313-1.3	D279S	Pathogenic	0.981
OPA1	O60313-1.3	D279T	Pathogenic	0.992
OPA1	O60313-1.3	D279V	Pathogenic	0.998
OPA1	O60313-1.3	D279W	Pathogenic	0.997
OPA1	O60313-1.3	D279Y	Pathogenic	0.998
OPA1	O60313-1.3	A280C	Pathogenic	0.52
OPA1	O60313-1.3	A280D	Pathogenic	0.861
OPA1	O60313-1.3	A280E	Pathogenic	0.692
OPA1	O60313-1.3	A280F	Pathogenic	0.784
OPA1	O60313-1.3	A280G	Pathogenic	0.603
OPA1	O60313-1.3	A280H	Pathogenic	0.927
OPA1	O60313-1.3	A280I	Pathogenic	0.563
OPA1	O60313-1.3	A280K	Pathogenic	0.597
OPA1	O60313-1.3	A280L	Pathogenic	0.586
OPA1	O60313-1.3	A280M	Pathogenic	0.685
OPA1	O60313-1.3	A280N	Pathogenic	0.876
OPA1	O60313-1.3	A280P	Pathogenic	0.798
OPA1	O60313-1.3	A280Q	Pathogenic	0.764
OPA1	O60313-1.3	A280R	Pathogenic	0.582
OPA1	O60313-1.3	A280S	Neutral	0.347
OPA1	O60313-1.3	A280T	Pathogenic	0.651
OPA1	O60313-1.3	A280V	Neutral	0.449
OPA1	O60313-1.3	A280W	Pathogenic	0.861
OPA1	O60313-1.3	A280Y	Pathogenic	0.883
OPA1	O60313-1.3	S281A	Neutral	0.104
OPA1	O60313-1.3	S281C	Neutral	0.338
OPA1	O60313-1.3	S281D	Neutral	0.183
OPA1	O60313-1.3	S281E	Neutral	0.192
OPA1	O60313-1.3	S281F	Neutral	0.371
OPA1	O60313-1.3	S281G	Neutral	0.293
OPA1	O60313-1.3	S281H	Neutral	0.497
OPA1	O60313-1.3	S281I	Neutral	0.377
OPA1	O60313-1.3	S281K	Neutral	0.135
OPA1	O60313-1.3	S281L	Neutral	0.4
OPA1	O60313-1.3	S281M	Neutral	0.261
OPA1	O60313-1.3	S281N	Neutral	0.082
OPA1	O60313-1.3	S281P	Neutral	0.39
OPA1	O60313-1.3	S281Q	Neutral	0.254
OPA1	O60313-1.3	S281R	Neutral	0.298
OPA1	O60313-1.3	S281T	Neutral	0.103
OPA1	O60313-1.3	S281V	Pathogenic	0.527
OPA1	O60313-1.3	S281W	Pathogenic	0.502
OPA1	O60313-1.3	S281Y	Pathogenic	0.552
OPA1	O60313-1.3	Y282A	Pathogenic	0.998
OPA1	O60313-1.3	Y282C	Pathogenic	0.999
OPA1	O60313-1.3	Y282D	Pathogenic	0.998
OPA1	O60313-1.3	Y282E	Pathogenic	0.996
OPA1	O60313-1.3	Y282F	Pathogenic	0.742
OPA1	O60313-1.3	Y282G	Pathogenic	0.999
OPA1	O60313-1.3	Y282H	Pathogenic	0.887
OPA1	O60313-1.3	Y282I	Pathogenic	0.995
OPA1	O60313-1.3	Y282K	Pathogenic	0.995
OPA1	O60313-1.3	Y282L	Pathogenic	0.995
OPA1	O60313-1.3	Y282M	Pathogenic	0.997
OPA1	O60313-1.3	Y282N	Pathogenic	0.996
OPA1	O60313-1.3	Y282P	Pathogenic	1.0
OPA1	O60313-1.3	Y282Q	Pathogenic	0.993
OPA1	O60313-1.3	Y282R	Pathogenic	0.995
OPA1	O60313-1.3	Y282S	Pathogenic	0.998
OPA1	O60313-1.3	Y282T	Pathogenic	0.998
OPA1	O60313-1.3	Y282V	Pathogenic	0.997
OPA1	O60313-1.3	Y282W	Pathogenic	0.837
OPA1	O60313-1.3	N283A	Pathogenic	0.973
OPA1	O60313-1.3	N283C	Pathogenic	0.984
OPA1	O60313-1.3	N283D	Pathogenic	0.761
OPA1	O60313-1.3	N283E	Pathogenic	0.91
OPA1	O60313-1.3	N283F	Pathogenic	0.963
OPA1	O60313-1.3	N283G	Pathogenic	0.841
OPA1	O60313-1.3	N283H	Pathogenic	0.641
OPA1	O60313-1.3	N283I	Pathogenic	0.964
OPA1	O60313-1.3	N283K	Pathogenic	0.869
OPA1	O60313-1.3	N283L	Pathogenic	0.967
OPA1	O60313-1.3	N283M	Pathogenic	0.94
OPA1	O60313-1.3	N283P	Pathogenic	0.964
OPA1	O60313-1.3	N283Q	Pathogenic	0.879
OPA1	O60313-1.3	N283R	Pathogenic	0.862
OPA1	O60313-1.3	N283S	Pathogenic	0.675
OPA1	O60313-1.3	N283T	Pathogenic	0.832
OPA1	O60313-1.3	N283V	Pathogenic	0.98
OPA1	O60313-1.3	N283W	Pathogenic	0.978
OPA1	O60313-1.3	N283Y	Pathogenic	0.949
OPA1	O60313-1.3	T284A	Pathogenic	0.951
OPA1	O60313-1.3	T284C	Pathogenic	0.97
OPA1	O60313-1.3	T284D	Pathogenic	0.962
OPA1	O60313-1.3	T284E	Pathogenic	0.964
OPA1	O60313-1.3	T284F	Pathogenic	0.975
OPA1	O60313-1.3	T284G	Pathogenic	0.992
OPA1	O60313-1.3	T284H	Pathogenic	0.994
OPA1	O60313-1.3	T284I	Pathogenic	0.934
OPA1	O60313-1.3	T284K	Pathogenic	0.947
OPA1	O60313-1.3	T284L	Pathogenic	0.939
OPA1	O60313-1.3	T284M	Pathogenic	0.96
OPA1	O60313-1.3	T284N	Pathogenic	0.91
OPA1	O60313-1.3	T284P	Pathogenic	0.977
OPA1	O60313-1.3	T284Q	Pathogenic	0.975
OPA1	O60313-1.3	T284R	Pathogenic	0.944
OPA1	O60313-1.3	T284S	Pathogenic	0.846
OPA1	O60313-1.3	T284V	Pathogenic	0.899
OPA1	O60313-1.3	T284W	Pathogenic	0.959
OPA1	O60313-1.3	T284Y	Pathogenic	0.988
OPA1	O60313-1.3	Q285A	Pathogenic	0.911
OPA1	O60313-1.3	Q285C	Pathogenic	0.98
OPA1	O60313-1.3	Q285D	Pathogenic	0.792
OPA1	O60313-1.3	Q285E	Neutral	0.353
OPA1	O60313-1.3	Q285F	Pathogenic	0.961
OPA1	O60313-1.3	Q285G	Pathogenic	0.974
OPA1	O60313-1.3	Q285H	Pathogenic	0.83
OPA1	O60313-1.3	Q285I	Pathogenic	0.962
OPA1	O60313-1.3	Q285K	Pathogenic	0.52
OPA1	O60313-1.3	Q285L	Pathogenic	0.905
OPA1	O60313-1.3	Q285M	Pathogenic	0.636
OPA1	O60313-1.3	Q285N	Pathogenic	0.819
OPA1	O60313-1.3	Q285P	Pathogenic	0.885
OPA1	O60313-1.3	Q285R	Pathogenic	0.504
OPA1	O60313-1.3	Q285S	Pathogenic	0.833
OPA1	O60313-1.3	Q285T	Pathogenic	0.922
OPA1	O60313-1.3	Q285V	Pathogenic	0.937
OPA1	O60313-1.3	Q285W	Pathogenic	0.833
OPA1	O60313-1.3	Q285Y	Pathogenic	0.859
OPA1	O60313-1.3	D286A	Pathogenic	0.997
OPA1	O60313-1.3	D286C	Pathogenic	0.998
OPA1	O60313-1.3	D286E	Pathogenic	0.914
OPA1	O60313-1.3	D286F	Pathogenic	0.995
OPA1	O60313-1.3	D286G	Pathogenic	0.992
OPA1	O60313-1.3	D286H	Pathogenic	0.992
OPA1	O60313-1.3	D286I	Pathogenic	0.995
OPA1	O60313-1.3	D286K	Pathogenic	0.995
OPA1	O60313-1.3	D286L	Pathogenic	0.999
OPA1	O60313-1.3	D286M	Pathogenic	0.997
OPA1	O60313-1.3	D286N	Pathogenic	0.969
OPA1	O60313-1.3	D286P	Pathogenic	0.988
OPA1	O60313-1.3	D286Q	Pathogenic	0.983
OPA1	O60313-1.3	D286R	Pathogenic	0.998
OPA1	O60313-1.3	D286S	Pathogenic	0.981
OPA1	O60313-1.3	D286T	Pathogenic	0.992
OPA1	O60313-1.3	D286V	Pathogenic	0.998
OPA1	O60313-1.3	D286W	Pathogenic	0.997
OPA1	O60313-1.3	D286Y	Pathogenic	0.998
OPA1	O60313-1.3	H287A	Pathogenic	0.998
OPA1	O60313-1.3	H287C	Pathogenic	0.999
OPA1	O60313-1.3	H287D	Pathogenic	0.989
OPA1	O60313-1.3	H287E	Pathogenic	0.975
OPA1	O60313-1.3	H287F	Pathogenic	0.98
OPA1	O60313-1.3	H287G	Pathogenic	0.998
OPA1	O60313-1.3	H287I	Pathogenic	0.998
OPA1	O60313-1.3	H287K	Pathogenic	0.987
OPA1	O60313-1.3	H287L	Pathogenic	0.998
OPA1	O60313-1.3	H287M	Pathogenic	0.996
OPA1	O60313-1.3	H287N	Pathogenic	0.929
OPA1	O60313-1.3	H287P	Pathogenic	0.997
OPA1	O60313-1.3	H287Q	Pathogenic	0.983
OPA1	O60313-1.3	H287R	Pathogenic	0.962
OPA1	O60313-1.3	H287S	Pathogenic	0.994
OPA1	O60313-1.3	H287T	Pathogenic	0.998
OPA1	O60313-1.3	H287V	Pathogenic	0.999
OPA1	O60313-1.3	H287W	Pathogenic	0.988
OPA1	O60313-1.3	H287Y	Pathogenic	0.806
OPA1	O60313-1.3	L288A	Pathogenic	0.98
OPA1	O60313-1.3	L288C	Pathogenic	0.99
OPA1	O60313-1.3	L288D	Pathogenic	0.998
OPA1	O60313-1.3	L288E	Pathogenic	0.995
OPA1	O60313-1.3	L288F	Pathogenic	0.985
OPA1	O60313-1.3	L288G	Pathogenic	0.999
OPA1	O60313-1.3	L288H	Pathogenic	0.998
OPA1	O60313-1.3	L288I	Pathogenic	0.89
OPA1	O60313-1.3	L288K	Pathogenic	0.981
OPA1	O60313-1.3	L288M	Pathogenic	0.852
OPA1	O60313-1.3	L288N	Pathogenic	0.995
OPA1	O60313-1.3	L288P	Pathogenic	0.998
OPA1	O60313-1.3	L288Q	Pathogenic	0.99
OPA1	O60313-1.3	L288R	Pathogenic	0.98
OPA1	O60313-1.3	L288S	Pathogenic	0.991
OPA1	O60313-1.3	L288T	Pathogenic	0.981
OPA1	O60313-1.3	L288V	Pathogenic	0.939
OPA1	O60313-1.3	L288W	Pathogenic	0.997
OPA1	O60313-1.3	L288Y	Pathogenic	0.99
OPA1	O60313-1.3	P289A	Pathogenic	0.995
OPA1	O60313-1.3	P289C	Pathogenic	1.0
OPA1	O60313-1.3	P289D	Pathogenic	0.989
OPA1	O60313-1.3	P289E	Pathogenic	0.989
OPA1	O60313-1.3	P289F	Pathogenic	1.0
OPA1	O60313-1.3	P289G	Pathogenic	0.998
OPA1	O60313-1.3	P289H	Pathogenic	0.998
OPA1	O60313-1.3	P289I	Pathogenic	0.999
OPA1	O60313-1.3	P289K	Pathogenic	0.984
OPA1	O60313-1.3	P289L	Pathogenic	0.999
OPA1	O60313-1.3	P289M	Pathogenic	0.998
OPA1	O60313-1.3	P289N	Pathogenic	0.997
OPA1	O60313-1.3	P289Q	Pathogenic	0.993
OPA1	O60313-1.3	P289R	Pathogenic	0.994
OPA1	O60313-1.3	P289S	Pathogenic	0.994
OPA1	O60313-1.3	P289T	Pathogenic	0.996
OPA1	O60313-1.3	P289V	Pathogenic	0.998
OPA1	O60313-1.3	P289W	Pathogenic	0.999
OPA1	O60313-1.3	P289Y	Pathogenic	0.999
OPA1	O60313-1.3	R290A	Pathogenic	0.983
OPA1	O60313-1.3	R290C	Pathogenic	0.997
OPA1	O60313-1.3	R290D	Pathogenic	0.998
OPA1	O60313-1.3	R290E	Pathogenic	0.983
OPA1	O60313-1.3	R290F	Pathogenic	0.994
OPA1	O60313-1.3	R290G	Pathogenic	0.995
OPA1	O60313-1.3	R290H	Pathogenic	0.966
OPA1	O60313-1.3	R290I	Pathogenic	0.994
OPA1	O60313-1.3	R290K	Pathogenic	0.91
OPA1	O60313-1.3	R290L	Pathogenic	0.983
OPA1	O60313-1.3	R290M	Pathogenic	0.969
OPA1	O60313-1.3	R290N	Pathogenic	0.981
OPA1	O60313-1.3	R290P	Pathogenic	0.992
OPA1	O60313-1.3	R290Q	Pathogenic	0.931
OPA1	O60313-1.3	R290S	Pathogenic	0.988
OPA1	O60313-1.3	R290T	Pathogenic	0.985
OPA1	O60313-1.3	R290V	Pathogenic	0.996
OPA1	O60313-1.3	R290W	Pathogenic	0.991
OPA1	O60313-1.3	R290Y	Pathogenic	0.992
OPA1	O60313-1.3	V291A	Pathogenic	0.975
OPA1	O60313-1.3	V291C	Pathogenic	0.996
OPA1	O60313-1.3	V291D	Pathogenic	0.997
OPA1	O60313-1.3	V291E	Pathogenic	0.994
OPA1	O60313-1.3	V291F	Pathogenic	0.994
OPA1	O60313-1.3	V291G	Pathogenic	0.999
OPA1	O60313-1.3	V291H	Pathogenic	0.999
OPA1	O60313-1.3	V291I	Pathogenic	0.7
OPA1	O60313-1.3	V291K	Pathogenic	0.99
OPA1	O60313-1.3	V291L	Pathogenic	0.956
OPA1	O60313-1.3	V291M	Pathogenic	0.971
OPA1	O60313-1.3	V291N	Pathogenic	0.998
OPA1	O60313-1.3	V291P	Pathogenic	0.998
OPA1	O60313-1.3	V291Q	Pathogenic	0.996
OPA1	O60313-1.3	V291R	Pathogenic	0.996
OPA1	O60313-1.3	V291S	Pathogenic	0.996
OPA1	O60313-1.3	V291T	Pathogenic	0.976
OPA1	O60313-1.3	V291W	Pathogenic	0.999
OPA1	O60313-1.3	V291Y	Pathogenic	0.995
OPA1	O60313-1.3	V292A	Pathogenic	0.952
OPA1	O60313-1.3	V292C	Pathogenic	0.991
OPA1	O60313-1.3	V292D	Pathogenic	0.995
OPA1	O60313-1.3	V292E	Pathogenic	0.988
OPA1	O60313-1.3	V292F	Pathogenic	0.988
OPA1	O60313-1.3	V292G	Pathogenic	0.997
OPA1	O60313-1.3	V292H	Pathogenic	0.998
OPA1	O60313-1.3	V292I	Pathogenic	0.54
OPA1	O60313-1.3	V292K	Pathogenic	0.981
OPA1	O60313-1.3	V292L	Pathogenic	0.915
OPA1	O60313-1.3	V292M	Pathogenic	0.943
OPA1	O60313-1.3	V292N	Pathogenic	0.996
OPA1	O60313-1.3	V292P	Pathogenic	0.996
OPA1	O60313-1.3	V292Q	Pathogenic	0.991
OPA1	O60313-1.3	V292R	Pathogenic	0.993
OPA1	O60313-1.3	V292S	Pathogenic	0.992
OPA1	O60313-1.3	V292T	Pathogenic	0.954
OPA1	O60313-1.3	V292W	Pathogenic	0.998
OPA1	O60313-1.3	V292Y	Pathogenic	0.991
OPA1	O60313-1.3	V293A	Pathogenic	0.959
OPA1	O60313-1.3	V293C	Pathogenic	0.993
OPA1	O60313-1.3	V293D	Pathogenic	0.996
OPA1	O60313-1.3	V293E	Pathogenic	0.989
OPA1	O60313-1.3	V293F	Pathogenic	0.989
OPA1	O60313-1.3	V293G	Pathogenic	0.997
OPA1	O60313-1.3	V293H	Pathogenic	0.998
OPA1	O60313-1.3	V293I	Pathogenic	0.578
OPA1	O60313-1.3	V293K	Pathogenic	0.984
OPA1	O60313-1.3	V293L	Pathogenic	0.927
OPA1	O60313-1.3	V293M	Pathogenic	0.951
OPA1	O60313-1.3	V293N	Pathogenic	0.996
OPA1	O60313-1.3	V293P	Pathogenic	0.997
OPA1	O60313-1.3	V293Q	Pathogenic	0.993
OPA1	O60313-1.3	V293R	Pathogenic	0.994
OPA1	O60313-1.3	V293S	Pathogenic	0.993
OPA1	O60313-1.3	V293T	Pathogenic	0.961
OPA1	O60313-1.3	V293W	Pathogenic	0.998
OPA1	O60313-1.3	V293Y	Pathogenic	0.992
OPA1	O60313-1.3	V294A	Pathogenic	0.959
OPA1	O60313-1.3	V294C	Pathogenic	0.993
OPA1	O60313-1.3	V294D	Pathogenic	0.996
OPA1	O60313-1.3	V294E	Pathogenic	0.989
OPA1	O60313-1.3	V294F	Pathogenic	0.989
OPA1	O60313-1.3	V294G	Pathogenic	0.997
OPA1	O60313-1.3	V294H	Pathogenic	0.998
OPA1	O60313-1.3	V294I	Pathogenic	0.578
OPA1	O60313-1.3	V294K	Pathogenic	0.984
OPA1	O60313-1.3	V294L	Pathogenic	0.927
OPA1	O60313-1.3	V294M	Pathogenic	0.951
OPA1	O60313-1.3	V294N	Pathogenic	0.996
OPA1	O60313-1.3	V294P	Pathogenic	0.997
OPA1	O60313-1.3	V294Q	Pathogenic	0.993
OPA1	O60313-1.3	V294R	Pathogenic	0.994
OPA1	O60313-1.3	V294S	Pathogenic	0.993
OPA1	O60313-1.3	V294T	Pathogenic	0.961
OPA1	O60313-1.3	V294W	Pathogenic	0.998
OPA1	O60313-1.3	V294Y	Pathogenic	0.992
OPA1	O60313-1.3	G295A	Pathogenic	0.883
OPA1	O60313-1.3	G295C	Pathogenic	0.989
OPA1	O60313-1.3	G295D	Pathogenic	0.929
OPA1	O60313-1.3	G295E	Pathogenic	0.976
OPA1	O60313-1.3	G295F	Pathogenic	0.974
OPA1	O60313-1.3	G295H	Pathogenic	0.984
OPA1	O60313-1.3	G295I	Pathogenic	0.991
OPA1	O60313-1.3	G295K	Pathogenic	0.964
OPA1	O60313-1.3	G295L	Pathogenic	0.992
OPA1	O60313-1.3	G295M	Pathogenic	0.985
OPA1	O60313-1.3	G295N	Pathogenic	0.838
OPA1	O60313-1.3	G295P	Pathogenic	0.976
OPA1	O60313-1.3	G295Q	Pathogenic	0.983
OPA1	O60313-1.3	G295R	Pathogenic	0.961
OPA1	O60313-1.3	G295S	Pathogenic	0.905
OPA1	O60313-1.3	G295T	Pathogenic	0.984
OPA1	O60313-1.3	G295V	Pathogenic	0.986
OPA1	O60313-1.3	G295W	Pathogenic	0.882
OPA1	O60313-1.3	G295Y	Pathogenic	0.987
OPA1	O60313-1.3	D296A	Pathogenic	0.963
OPA1	O60313-1.3	D296C	Pathogenic	0.977
OPA1	O60313-1.3	D296E	Neutral	0.471
OPA1	O60313-1.3	D296F	Pathogenic	0.947
OPA1	O60313-1.3	D296G	Pathogenic	0.917
OPA1	O60313-1.3	D296H	Pathogenic	0.912
OPA1	O60313-1.3	D296I	Pathogenic	0.949
OPA1	O60313-1.3	D296K	Pathogenic	0.948
OPA1	O60313-1.3	D296L	Pathogenic	0.983
OPA1	O60313-1.3	D296M	Pathogenic	0.969
OPA1	O60313-1.3	D296N	Pathogenic	0.724
OPA1	O60313-1.3	D296P	Pathogenic	0.87
OPA1	O60313-1.3	D296Q	Pathogenic	0.834
OPA1	O60313-1.3	D296R	Pathogenic	0.98
OPA1	O60313-1.3	D296S	Pathogenic	0.812
OPA1	O60313-1.3	D296T	Pathogenic	0.91
OPA1	O60313-1.3	D296V	Pathogenic	0.971
OPA1	O60313-1.3	D296W	Pathogenic	0.968
OPA1	O60313-1.3	D296Y	Pathogenic	0.974
OPA1	O60313-1.3	Q297A	Pathogenic	0.944
OPA1	O60313-1.3	Q297C	Pathogenic	0.988
OPA1	O60313-1.3	Q297D	Pathogenic	0.862
OPA1	O60313-1.3	Q297E	Neutral	0.473
OPA1	O60313-1.3	Q297F	Pathogenic	0.976
OPA1	O60313-1.3	Q297G	Pathogenic	0.984
OPA1	O60313-1.3	Q297H	Pathogenic	0.889
OPA1	O60313-1.3	Q297I	Pathogenic	0.976
OPA1	O60313-1.3	Q297K	Pathogenic	0.639
OPA1	O60313-1.3	Q297L	Pathogenic	0.94
OPA1	O60313-1.3	Q297M	Pathogenic	0.742
OPA1	O60313-1.3	Q297N	Pathogenic	0.881
OPA1	O60313-1.3	Q297P	Pathogenic	0.927
OPA1	O60313-1.3	Q297R	Pathogenic	0.625
OPA1	O60313-1.3	Q297S	Pathogenic	0.891
OPA1	O60313-1.3	Q297T	Pathogenic	0.951
OPA1	O60313-1.3	Q297V	Pathogenic	0.961
OPA1	O60313-1.3	Q297W	Pathogenic	0.891
OPA1	O60313-1.3	Q297Y	Pathogenic	0.909
OPA1	O60313-1.3	S298A	Pathogenic	0.681
OPA1	O60313-1.3	S298C	Pathogenic	0.904
OPA1	O60313-1.3	S298D	Pathogenic	0.806
OPA1	O60313-1.3	S298E	Pathogenic	0.814
OPA1	O60313-1.3	S298F	Pathogenic	0.916
OPA1	O60313-1.3	S298G	Pathogenic	0.884
OPA1	O60313-1.3	S298H	Pathogenic	0.948
OPA1	O60313-1.3	S298I	Pathogenic	0.918
OPA1	O60313-1.3	S298K	Pathogenic	0.742
OPA1	O60313-1.3	S298L	Pathogenic	0.925
OPA1	O60313-1.3	S298M	Pathogenic	0.867
OPA1	O60313-1.3	S298N	Pathogenic	0.621
OPA1	O60313-1.3	S298P	Pathogenic	0.922
OPA1	O60313-1.3	S298Q	Pathogenic	0.863
OPA1	O60313-1.3	S298R	Pathogenic	0.887
OPA1	O60313-1.3	S298T	Pathogenic	0.68
OPA1	O60313-1.3	S298V	Pathogenic	0.954
OPA1	O60313-1.3	S298W	Pathogenic	0.949
OPA1	O60313-1.3	S298Y	Pathogenic	0.958
OPA1	O60313-1.3	A299C	Neutral	0.201
OPA1	O60313-1.3	A299D	Pathogenic	0.589
OPA1	O60313-1.3	A299E	Neutral	0.343
OPA1	O60313-1.3	A299F	Neutral	0.456
OPA1	O60313-1.3	A299G	Neutral	0.26
OPA1	O60313-1.3	A299H	Pathogenic	0.747
OPA1	O60313-1.3	A299I	Neutral	0.229
OPA1	O60313-1.3	A299K	Neutral	0.255
OPA1	O60313-1.3	A299L	Neutral	0.247
OPA1	O60313-1.3	A299M	Neutral	0.335
OPA1	O60313-1.3	A299N	Pathogenic	0.621
OPA1	O60313-1.3	A299P	Neutral	0.477
OPA1	O60313-1.3	A299Q	Neutral	0.428
OPA1	O60313-1.3	A299R	Neutral	0.244
OPA1	O60313-1.3	A299S	Neutral	0.109
OPA1	O60313-1.3	A299T	Neutral	0.302
OPA1	O60313-1.3	A299V	Neutral	0.159
OPA1	O60313-1.3	A299W	Pathogenic	0.59
OPA1	O60313-1.3	A299Y	Pathogenic	0.637
OPA1	O60313-1.3	G300A	Pathogenic	0.883
OPA1	O60313-1.3	G300C	Pathogenic	0.989
OPA1	O60313-1.3	G300D	Pathogenic	0.929
OPA1	O60313-1.3	G300E	Pathogenic	0.976
OPA1	O60313-1.3	G300F	Pathogenic	0.974
OPA1	O60313-1.3	G300H	Pathogenic	0.984
OPA1	O60313-1.3	G300I	Pathogenic	0.991
OPA1	O60313-1.3	G300K	Pathogenic	0.964
OPA1	O60313-1.3	G300L	Pathogenic	0.992
OPA1	O60313-1.3	G300M	Pathogenic	0.985
OPA1	O60313-1.3	G300N	Pathogenic	0.838
OPA1	O60313-1.3	G300P	Pathogenic	0.976
OPA1	O60313-1.3	G300Q	Pathogenic	0.983
OPA1	O60313-1.3	G300R	Pathogenic	0.961
OPA1	O60313-1.3	G300S	Pathogenic	0.905
OPA1	O60313-1.3	G300T	Pathogenic	0.984
OPA1	O60313-1.3	G300V	Pathogenic	0.986
OPA1	O60313-1.3	G300W	Pathogenic	0.882
OPA1	O60313-1.3	G300Y	Pathogenic	0.987
OPA1	O60313-1.3	K301A	Pathogenic	0.843
OPA1	O60313-1.3	K301C	Pathogenic	0.963
OPA1	O60313-1.3	K301D	Pathogenic	0.94
OPA1	O60313-1.3	K301E	Pathogenic	0.64
OPA1	O60313-1.3	K301F	Pathogenic	0.938
OPA1	O60313-1.3	K301G	Pathogenic	0.951
OPA1	O60313-1.3	K301H	Pathogenic	0.884
OPA1	O60313-1.3	K301I	Pathogenic	0.934
OPA1	O60313-1.3	K301L	Pathogenic	0.844
OPA1	O60313-1.3	K301M	Pathogenic	0.741
OPA1	O60313-1.3	K301N	Pathogenic	0.826
OPA1	O60313-1.3	K301P	Pathogenic	0.801
OPA1	O60313-1.3	K301Q	Pathogenic	0.553
OPA1	O60313-1.3	K301R	Neutral	0.467
OPA1	O60313-1.3	K301S	Pathogenic	0.722
OPA1	O60313-1.3	K301T	Pathogenic	0.861
OPA1	O60313-1.3	K301V	Pathogenic	0.887
OPA1	O60313-1.3	K301W	Pathogenic	0.899
OPA1	O60313-1.3	K301Y	Pathogenic	0.915
OPA1	O60313-1.3	T302A	Pathogenic	0.892
OPA1	O60313-1.3	T302C	Pathogenic	0.933
OPA1	O60313-1.3	T302D	Pathogenic	0.914
OPA1	O60313-1.3	T302E	Pathogenic	0.92
OPA1	O60313-1.3	T302F	Pathogenic	0.944
OPA1	O60313-1.3	T302G	Pathogenic	0.982
OPA1	O60313-1.3	T302H	Pathogenic	0.985
OPA1	O60313-1.3	T302I	Pathogenic	0.856
OPA1	O60313-1.3	T302K	Pathogenic	0.883
OPA1	O60313-1.3	T302L	Pathogenic	0.867
OPA1	O60313-1.3	T302M	Pathogenic	0.91
OPA1	O60313-1.3	T302N	Pathogenic	0.811
OPA1	O60313-1.3	T302P	Pathogenic	0.947
OPA1	O60313-1.3	T302Q	Pathogenic	0.943
OPA1	O60313-1.3	T302R	Pathogenic	0.876
OPA1	O60313-1.3	T302S	Pathogenic	0.699
OPA1	O60313-1.3	T302V	Pathogenic	0.79
OPA1	O60313-1.3	T302W	Pathogenic	0.908
OPA1	O60313-1.3	T302Y	Pathogenic	0.972
OPA1	O60313-1.3	S303A	Pathogenic	0.946
OPA1	O60313-1.3	S303C	Pathogenic	0.987
OPA1	O60313-1.3	S303D	Pathogenic	0.972
OPA1	O60313-1.3	S303E	Pathogenic	0.973
OPA1	O60313-1.3	S303F	Pathogenic	0.989
OPA1	O60313-1.3	S303G	Pathogenic	0.984
OPA1	O60313-1.3	S303H	Pathogenic	0.993
OPA1	O60313-1.3	S303I	Pathogenic	0.989
OPA1	O60313-1.3	S303K	Pathogenic	0.96
OPA1	O60313-1.3	S303L	Pathogenic	0.99
OPA1	O60313-1.3	S303M	Pathogenic	0.982
OPA1	O60313-1.3	S303N	Pathogenic	0.931
OPA1	O60313-1.3	S303P	Pathogenic	0.99
OPA1	O60313-1.3	S303Q	Pathogenic	0.981
OPA1	O60313-1.3	S303R	Pathogenic	0.985
OPA1	O60313-1.3	S303T	Pathogenic	0.946
OPA1	O60313-1.3	S303V	Pathogenic	0.994
OPA1	O60313-1.3	S303W	Pathogenic	0.994
OPA1	O60313-1.3	S303Y	Pathogenic	0.995
OPA1	O60313-1.3	V304A	Pathogenic	0.965
OPA1	O60313-1.3	V304C	Pathogenic	0.994
OPA1	O60313-1.3	V304D	Pathogenic	0.996
OPA1	O60313-1.3	V304E	Pathogenic	0.991
OPA1	O60313-1.3	V304F	Pathogenic	0.991
OPA1	O60313-1.3	V304G	Pathogenic	0.998
OPA1	O60313-1.3	V304H	Pathogenic	0.998
OPA1	O60313-1.3	V304I	Pathogenic	0.617
OPA1	O60313-1.3	V304K	Pathogenic	0.986
OPA1	O60313-1.3	V304L	Pathogenic	0.937
OPA1	O60313-1.3	V304M	Pathogenic	0.958
OPA1	O60313-1.3	V304N	Pathogenic	0.997
OPA1	O60313-1.3	V304P	Pathogenic	0.997
OPA1	O60313-1.3	V304Q	Pathogenic	0.994
OPA1	O60313-1.3	V304R	Pathogenic	0.995
OPA1	O60313-1.3	V304S	Pathogenic	0.994
OPA1	O60313-1.3	V304T	Pathogenic	0.966
OPA1	O60313-1.3	V304W	Pathogenic	0.998
OPA1	O60313-1.3	V304Y	Pathogenic	0.993
OPA1	O60313-1.3	L305A	Pathogenic	0.975
OPA1	O60313-1.3	L305C	Pathogenic	0.987
OPA1	O60313-1.3	L305D	Pathogenic	0.997
OPA1	O60313-1.3	L305E	Pathogenic	0.994
OPA1	O60313-1.3	L305F	Pathogenic	0.981
OPA1	O60313-1.3	L305G	Pathogenic	0.998
OPA1	O60313-1.3	L305H	Pathogenic	0.997
OPA1	O60313-1.3	L305I	Pathogenic	0.865
OPA1	O60313-1.3	L305K	Pathogenic	0.976
OPA1	O60313-1.3	L305M	Pathogenic	0.821
OPA1	O60313-1.3	L305N	Pathogenic	0.994
OPA1	O60313-1.3	L305P	Pathogenic	0.998
OPA1	O60313-1.3	L305Q	Pathogenic	0.988
OPA1	O60313-1.3	L305R	Pathogenic	0.974
OPA1	O60313-1.3	L305S	Pathogenic	0.988
OPA1	O60313-1.3	L305T	Pathogenic	0.976
OPA1	O60313-1.3	L305V	Pathogenic	0.924
OPA1	O60313-1.3	L305W	Pathogenic	0.996
OPA1	O60313-1.3	L305Y	Pathogenic	0.988
OPA1	O60313-1.3	E306A	Pathogenic	0.985
OPA1	O60313-1.3	E306C	Pathogenic	0.999
OPA1	O60313-1.3	E306D	Pathogenic	0.863
OPA1	O60313-1.3	E306F	Pathogenic	0.993
OPA1	O60313-1.3	E306G	Pathogenic	0.996
OPA1	O60313-1.3	E306H	Pathogenic	0.968
OPA1	O60313-1.3	E306I	Pathogenic	0.994
OPA1	O60313-1.3	E306K	Pathogenic	0.935
OPA1	O60313-1.3	E306L	Pathogenic	0.994
OPA1	O60313-1.3	E306M	Pathogenic	0.989
OPA1	O60313-1.3	E306N	Pathogenic	0.983
OPA1	O60313-1.3	E306P	Pathogenic	0.98
OPA1	O60313-1.3	E306Q	Pathogenic	0.835
OPA1	O60313-1.3	E306R	Pathogenic	0.975
OPA1	O60313-1.3	E306S	Pathogenic	0.97
OPA1	O60313-1.3	E306T	Pathogenic	0.987
OPA1	O60313-1.3	E306V	Pathogenic	0.99
OPA1	O60313-1.3	E306W	Pathogenic	0.989
OPA1	O60313-1.3	E306Y	Pathogenic	0.991
OPA1	O60313-1.3	M307A	Pathogenic	0.979
OPA1	O60313-1.3	M307C	Pathogenic	0.989
OPA1	O60313-1.3	M307D	Pathogenic	0.994
OPA1	O60313-1.3	M307E	Pathogenic	0.985
OPA1	O60313-1.3	M307F	Pathogenic	0.964
OPA1	O60313-1.3	M307G	Pathogenic	0.996
OPA1	O60313-1.3	M307H	Pathogenic	0.993
OPA1	O60313-1.3	M307I	Pathogenic	0.904
OPA1	O60313-1.3	M307K	Pathogenic	0.944
OPA1	O60313-1.3	M307L	Pathogenic	0.782
OPA1	O60313-1.3	M307N	Pathogenic	0.985
OPA1	O60313-1.3	M307P	Pathogenic	0.995
OPA1	O60313-1.3	M307Q	Pathogenic	0.922
OPA1	O60313-1.3	M307R	Pathogenic	0.941
OPA1	O60313-1.3	M307S	Pathogenic	0.972
OPA1	O60313-1.3	M307T	Pathogenic	0.98
OPA1	O60313-1.3	M307V	Pathogenic	0.936
OPA1	O60313-1.3	M307W	Pathogenic	0.979
OPA1	O60313-1.3	M307Y	Pathogenic	0.99
OPA1	O60313-1.3	I308A	Pathogenic	0.949
OPA1	O60313-1.3	I308C	Pathogenic	0.974
OPA1	O60313-1.3	I308D	Pathogenic	0.985
OPA1	O60313-1.3	I308E	Pathogenic	0.987
OPA1	O60313-1.3	I308F	Pathogenic	0.967
OPA1	O60313-1.3	I308G	Pathogenic	0.997
OPA1	O60313-1.3	I308H	Pathogenic	0.994
OPA1	O60313-1.3	I308K	Pathogenic	0.983
OPA1	O60313-1.3	I308L	Pathogenic	0.771
OPA1	O60313-1.3	I308M	Pathogenic	0.864
OPA1	O60313-1.3	I308N	Pathogenic	0.987
OPA1	O60313-1.3	I308P	Pathogenic	0.996
OPA1	O60313-1.3	I308Q	Pathogenic	0.991
OPA1	O60313-1.3	I308R	Pathogenic	0.982
OPA1	O60313-1.3	I308S	Pathogenic	0.976
OPA1	O60313-1.3	I308T	Pathogenic	0.951
OPA1	O60313-1.3	I308V	Neutral	0.41
OPA1	O60313-1.3	I308W	Pathogenic	0.998
OPA1	O60313-1.3	I308Y	Pathogenic	0.975
OPA1	O60313-1.3	A309C	Pathogenic	0.974
OPA1	O60313-1.3	A309D	Pathogenic	0.995
OPA1	O60313-1.3	A309E	Pathogenic	0.987
OPA1	O60313-1.3	A309F	Pathogenic	0.992
OPA1	O60313-1.3	A309G	Pathogenic	0.982
OPA1	O60313-1.3	A309H	Pathogenic	0.998
OPA1	O60313-1.3	A309I	Pathogenic	0.978
OPA1	O60313-1.3	A309K	Pathogenic	0.981
OPA1	O60313-1.3	A309L	Pathogenic	0.98
OPA1	O60313-1.3	A309M	Pathogenic	0.987
OPA1	O60313-1.3	A309N	Pathogenic	0.996
OPA1	O60313-1.3	A309P	Pathogenic	0.993
OPA1	O60313-1.3	A309Q	Pathogenic	0.991
OPA1	O60313-1.3	A309R	Pathogenic	0.98
OPA1	O60313-1.3	A309S	Pathogenic	0.949
OPA1	O60313-1.3	A309T	Pathogenic	0.985
OPA1	O60313-1.3	A309V	Pathogenic	0.966
OPA1	O60313-1.3	A309W	Pathogenic	0.995
OPA1	O60313-1.3	A309Y	Pathogenic	0.996
OPA1	O60313-1.3	Q310A	Pathogenic	0.98
OPA1	O60313-1.3	Q310C	Pathogenic	0.996
OPA1	O60313-1.3	Q310D	Pathogenic	0.948
OPA1	O60313-1.3	Q310E	Pathogenic	0.724
OPA1	O60313-1.3	Q310F	Pathogenic	0.992
OPA1	O60313-1.3	Q310G	Pathogenic	0.994
OPA1	O60313-1.3	Q310H	Pathogenic	0.959
OPA1	O60313-1.3	Q310I	Pathogenic	0.992
OPA1	O60313-1.3	Q310K	Pathogenic	0.839
OPA1	O60313-1.3	Q310L	Pathogenic	0.979
OPA1	O60313-1.3	Q310M	Pathogenic	0.894
OPA1	O60313-1.3	Q310N	Pathogenic	0.956
OPA1	O60313-1.3	Q310P	Pathogenic	0.974
OPA1	O60313-1.3	Q310R	Pathogenic	0.83
OPA1	O60313-1.3	Q310S	Pathogenic	0.96
OPA1	O60313-1.3	Q310T	Pathogenic	0.983
OPA1	O60313-1.3	Q310V	Pathogenic	0.986
OPA1	O60313-1.3	Q310W	Pathogenic	0.96
OPA1	O60313-1.3	Q310Y	Pathogenic	0.967
OPA1	O60313-1.3	A311C	Pathogenic	0.974
OPA1	O60313-1.3	A311D	Pathogenic	0.995
OPA1	O60313-1.3	A311E	Pathogenic	0.987
OPA1	O60313-1.3	A311F	Pathogenic	0.992
OPA1	O60313-1.3	A311G	Pathogenic	0.982
OPA1	O60313-1.3	A311H	Pathogenic	0.998
OPA1	O60313-1.3	A311I	Pathogenic	0.978
OPA1	O60313-1.3	A311K	Pathogenic	0.981
OPA1	O60313-1.3	A311L	Pathogenic	0.98
OPA1	O60313-1.3	A311M	Pathogenic	0.987
OPA1	O60313-1.3	A311N	Pathogenic	0.996
OPA1	O60313-1.3	A311P	Pathogenic	0.993
OPA1	O60313-1.3	A311Q	Pathogenic	0.991
OPA1	O60313-1.3	A311R	Pathogenic	0.98
OPA1	O60313-1.3	A311S	Pathogenic	0.949
OPA1	O60313-1.3	A311T	Pathogenic	0.985
OPA1	O60313-1.3	A311V	Pathogenic	0.966
OPA1	O60313-1.3	A311W	Pathogenic	0.995
OPA1	O60313-1.3	A311Y	Pathogenic	0.996
OPA1	O60313-1.3	R312A	Pathogenic	0.979
OPA1	O60313-1.3	R312C	Pathogenic	0.996
OPA1	O60313-1.3	R312D	Pathogenic	0.997
OPA1	O60313-1.3	R312E	Pathogenic	0.978
OPA1	O60313-1.3	R312F	Pathogenic	0.992
OPA1	O60313-1.3	R312G	Pathogenic	0.994
OPA1	O60313-1.3	R312H	Pathogenic	0.958
OPA1	O60313-1.3	R312I	Pathogenic	0.992
OPA1	O60313-1.3	R312K	Pathogenic	0.89
OPA1	O60313-1.3	R312L	Pathogenic	0.979
OPA1	O60313-1.3	R312M	Pathogenic	0.961
OPA1	O60313-1.3	R312N	Pathogenic	0.976
OPA1	O60313-1.3	R312P	Pathogenic	0.99
OPA1	O60313-1.3	R312Q	Pathogenic	0.914
OPA1	O60313-1.3	R312S	Pathogenic	0.985
OPA1	O60313-1.3	R312T	Pathogenic	0.982
OPA1	O60313-1.3	R312V	Pathogenic	0.995
OPA1	O60313-1.3	R312W	Pathogenic	0.988
OPA1	O60313-1.3	R312Y	Pathogenic	0.99
OPA1	O60313-1.3	I313A	Pathogenic	0.979
OPA1	O60313-1.3	I313C	Pathogenic	0.989
OPA1	O60313-1.3	I313D	Pathogenic	0.994
OPA1	O60313-1.3	I313E	Pathogenic	0.995
OPA1	O60313-1.3	I313F	Pathogenic	0.987
OPA1	O60313-1.3	I313G	Pathogenic	0.999
OPA1	O60313-1.3	I313H	Pathogenic	0.998
OPA1	O60313-1.3	I313K	Pathogenic	0.993
OPA1	O60313-1.3	I313L	Pathogenic	0.895
OPA1	O60313-1.3	I313M	Pathogenic	0.941
OPA1	O60313-1.3	I313N	Pathogenic	0.995
OPA1	O60313-1.3	I313P	Pathogenic	0.998
OPA1	O60313-1.3	I313Q	Pathogenic	0.997
OPA1	O60313-1.3	I313R	Pathogenic	0.993
OPA1	O60313-1.3	I313S	Pathogenic	0.99
OPA1	O60313-1.3	I313T	Pathogenic	0.98
OPA1	O60313-1.3	I313V	Pathogenic	0.637
OPA1	O60313-1.3	I313W	Pathogenic	0.999
OPA1	O60313-1.3	I313Y	Pathogenic	0.99
OPA1	O60313-1.3	F314A	Pathogenic	0.994
OPA1	O60313-1.3	F314C	Pathogenic	0.997
OPA1	O60313-1.3	F314D	Pathogenic	0.995
OPA1	O60313-1.3	F314E	Pathogenic	0.996
OPA1	O60313-1.3	F314G	Pathogenic	0.997
OPA1	O60313-1.3	F314H	Pathogenic	0.982
OPA1	O60313-1.3	F314I	Pathogenic	0.989
OPA1	O60313-1.3	F314K	Pathogenic	0.994
OPA1	O60313-1.3	F314L	Pathogenic	0.988
OPA1	O60313-1.3	F314M	Pathogenic	0.982
OPA1	O60313-1.3	F314N	Pathogenic	0.996
OPA1	O60313-1.3	F314P	Pathogenic	1.0
OPA1	O60313-1.3	F314Q	Pathogenic	0.997
OPA1	O60313-1.3	F314R	Pathogenic	0.994
OPA1	O60313-1.3	F314S	Pathogenic	0.992
OPA1	O60313-1.3	F314T	Pathogenic	0.994
OPA1	O60313-1.3	F314V	Pathogenic	0.993
OPA1	O60313-1.3	F314W	Pathogenic	0.95
OPA1	O60313-1.3	F314Y	Pathogenic	0.638
OPA1	O60313-1.3	P315A	Pathogenic	0.994
OPA1	O60313-1.3	P315C	Pathogenic	0.999
OPA1	O60313-1.3	P315D	Pathogenic	0.986
OPA1	O60313-1.3	P315E	Pathogenic	0.987
OPA1	O60313-1.3	P315F	Pathogenic	1.0
OPA1	O60313-1.3	P315G	Pathogenic	0.997
OPA1	O60313-1.3	P315H	Pathogenic	0.998
OPA1	O60313-1.3	P315I	Pathogenic	0.999
OPA1	O60313-1.3	P315K	Pathogenic	0.98
OPA1	O60313-1.3	P315L	Pathogenic	0.999
OPA1	O60313-1.3	P315M	Pathogenic	0.998
OPA1	O60313-1.3	P315N	Pathogenic	0.996
OPA1	O60313-1.3	P315Q	Pathogenic	0.991
OPA1	O60313-1.3	P315R	Pathogenic	0.993
OPA1	O60313-1.3	P315S	Pathogenic	0.992
OPA1	O60313-1.3	P315T	Pathogenic	0.994
OPA1	O60313-1.3	P315V	Pathogenic	0.998
OPA1	O60313-1.3	P315W	Pathogenic	0.999
OPA1	O60313-1.3	P315Y	Pathogenic	0.999
OPA1	O60313-1.3	R316A	Pathogenic	0.979
OPA1	O60313-1.3	R316C	Pathogenic	0.996
OPA1	O60313-1.3	R316D	Pathogenic	0.997
OPA1	O60313-1.3	R316E	Pathogenic	0.978
OPA1	O60313-1.3	R316F	Pathogenic	0.992
OPA1	O60313-1.3	R316G	Pathogenic	0.994
OPA1	O60313-1.3	R316H	Pathogenic	0.958
OPA1	O60313-1.3	R316I	Pathogenic	0.992
OPA1	O60313-1.3	R316K	Pathogenic	0.89
OPA1	O60313-1.3	R316L	Pathogenic	0.979
OPA1	O60313-1.3	R316M	Pathogenic	0.961
OPA1	O60313-1.3	R316N	Pathogenic	0.976
OPA1	O60313-1.3	R316P	Pathogenic	0.99
OPA1	O60313-1.3	R316Q	Pathogenic	0.914
OPA1	O60313-1.3	R316S	Pathogenic	0.985
OPA1	O60313-1.3	R316T	Pathogenic	0.982
OPA1	O60313-1.3	R316V	Pathogenic	0.995
OPA1	O60313-1.3	R316W	Pathogenic	0.988
OPA1	O60313-1.3	R316Y	Pathogenic	0.99
OPA1	O60313-1.3	G317A	Pathogenic	0.984
OPA1	O60313-1.3	G317C	Pathogenic	0.999
OPA1	O60313-1.3	G317D	Pathogenic	0.991
OPA1	O60313-1.3	G317E	Pathogenic	0.997
OPA1	O60313-1.3	G317F	Pathogenic	0.997
OPA1	O60313-1.3	G317H	Pathogenic	0.998
OPA1	O60313-1.3	G317I	Pathogenic	0.999
OPA1	O60313-1.3	G317K	Pathogenic	0.995
OPA1	O60313-1.3	G317L	Pathogenic	0.999
OPA1	O60313-1.3	G317M	Pathogenic	0.998
OPA1	O60313-1.3	G317N	Pathogenic	0.977
OPA1	O60313-1.3	G317P	Pathogenic	0.997
OPA1	O60313-1.3	G317Q	Pathogenic	0.998
OPA1	O60313-1.3	G317R	Pathogenic	0.995
OPA1	O60313-1.3	G317S	Pathogenic	0.987
OPA1	O60313-1.3	G317T	Pathogenic	0.998
OPA1	O60313-1.3	G317V	Pathogenic	0.998
OPA1	O60313-1.3	G317W	Pathogenic	0.984
OPA1	O60313-1.3	G317Y	Pathogenic	0.998
OPA1	O60313-1.3	S318A	Pathogenic	0.52
OPA1	O60313-1.3	S318C	Pathogenic	0.827
OPA1	O60313-1.3	S318D	Pathogenic	0.677
OPA1	O60313-1.3	S318E	Pathogenic	0.689
OPA1	O60313-1.3	S318F	Pathogenic	0.846
OPA1	O60313-1.3	S318G	Pathogenic	0.795
OPA1	O60313-1.3	S318H	Pathogenic	0.902
OPA1	O60313-1.3	S318I	Pathogenic	0.85
OPA1	O60313-1.3	S318K	Pathogenic	0.593
OPA1	O60313-1.3	S318L	Pathogenic	0.862
OPA1	O60313-1.3	S318M	Pathogenic	0.767
OPA1	O60313-1.3	S318N	Neutral	0.453
OPA1	O60313-1.3	S318P	Pathogenic	0.857
OPA1	O60313-1.3	S318Q	Pathogenic	0.761
OPA1	O60313-1.3	S318R	Pathogenic	0.799
OPA1	O60313-1.3	S318T	Pathogenic	0.518
OPA1	O60313-1.3	S318V	Pathogenic	0.912
OPA1	O60313-1.3	S318W	Pathogenic	0.904
OPA1	O60313-1.3	S318Y	Pathogenic	0.92
OPA1	O60313-1.3	G319A	Pathogenic	0.984
OPA1	O60313-1.3	G319C	Pathogenic	0.999
OPA1	O60313-1.3	G319D	Pathogenic	0.991
OPA1	O60313-1.3	G319E	Pathogenic	0.997
OPA1	O60313-1.3	G319F	Pathogenic	0.997
OPA1	O60313-1.3	G319H	Pathogenic	0.998
OPA1	O60313-1.3	G319I	Pathogenic	0.999
OPA1	O60313-1.3	G319K	Pathogenic	0.995
OPA1	O60313-1.3	G319L	Pathogenic	0.999
OPA1	O60313-1.3	G319M	Pathogenic	0.998
OPA1	O60313-1.3	G319N	Pathogenic	0.977
OPA1	O60313-1.3	G319P	Pathogenic	0.997
OPA1	O60313-1.3	G319Q	Pathogenic	0.998
OPA1	O60313-1.3	G319R	Pathogenic	0.995
OPA1	O60313-1.3	G319S	Pathogenic	0.987
OPA1	O60313-1.3	G319T	Pathogenic	0.998
OPA1	O60313-1.3	G319V	Pathogenic	0.998
OPA1	O60313-1.3	G319W	Pathogenic	0.984
OPA1	O60313-1.3	G319Y	Pathogenic	0.998
OPA1	O60313-1.3	E320A	Pathogenic	0.985
OPA1	O60313-1.3	E320C	Pathogenic	0.999
OPA1	O60313-1.3	E320D	Pathogenic	0.863
OPA1	O60313-1.3	E320F	Pathogenic	0.993
OPA1	O60313-1.3	E320G	Pathogenic	0.996
OPA1	O60313-1.3	E320H	Pathogenic	0.968
OPA1	O60313-1.3	E320I	Pathogenic	0.994
OPA1	O60313-1.3	E320K	Pathogenic	0.935
OPA1	O60313-1.3	E320L	Pathogenic	0.994
OPA1	O60313-1.3	E320M	Pathogenic	0.989
OPA1	O60313-1.3	E320N	Pathogenic	0.983
OPA1	O60313-1.3	E320P	Pathogenic	0.98
OPA1	O60313-1.3	E320Q	Pathogenic	0.835
OPA1	O60313-1.3	E320R	Pathogenic	0.975
OPA1	O60313-1.3	E320S	Pathogenic	0.97
OPA1	O60313-1.3	E320T	Pathogenic	0.987
OPA1	O60313-1.3	E320V	Pathogenic	0.99
OPA1	O60313-1.3	E320W	Pathogenic	0.989
OPA1	O60313-1.3	E320Y	Pathogenic	0.991
OPA1	O60313-1.3	M321A	Pathogenic	0.991
OPA1	O60313-1.3	M321C	Pathogenic	0.995
OPA1	O60313-1.3	M321D	Pathogenic	0.997
OPA1	O60313-1.3	M321E	Pathogenic	0.994
OPA1	O60313-1.3	M321F	Pathogenic	0.985
OPA1	O60313-1.3	M321G	Pathogenic	0.998
OPA1	O60313-1.3	M321H	Pathogenic	0.997
OPA1	O60313-1.3	M321I	Pathogenic	0.958
OPA1	O60313-1.3	M321K	Pathogenic	0.976
OPA1	O60313-1.3	M321L	Pathogenic	0.895
OPA1	O60313-1.3	M321N	Pathogenic	0.994
OPA1	O60313-1.3	M321P	Pathogenic	0.998
OPA1	O60313-1.3	M321Q	Pathogenic	0.966
OPA1	O60313-1.3	M321R	Pathogenic	0.974
OPA1	O60313-1.3	M321S	Pathogenic	0.988
OPA1	O60313-1.3	M321T	Pathogenic	0.992
OPA1	O60313-1.3	M321V	Pathogenic	0.972
OPA1	O60313-1.3	M321W	Pathogenic	0.991
OPA1	O60313-1.3	M321Y	Pathogenic	0.996
OPA1	O60313-1.3	M322A	Pathogenic	0.991
OPA1	O60313-1.3	M322C	Pathogenic	0.995
OPA1	O60313-1.3	M322D	Pathogenic	0.997
OPA1	O60313-1.3	M322E	Pathogenic	0.994
OPA1	O60313-1.3	M322F	Pathogenic	0.985
OPA1	O60313-1.3	M322G	Pathogenic	0.998
OPA1	O60313-1.3	M322H	Pathogenic	0.997
OPA1	O60313-1.3	M322I	Pathogenic	0.958
OPA1	O60313-1.3	M322K	Pathogenic	0.976
OPA1	O60313-1.3	M322L	Pathogenic	0.895
OPA1	O60313-1.3	M322N	Pathogenic	0.994
OPA1	O60313-1.3	M322P	Pathogenic	0.998
OPA1	O60313-1.3	M322Q	Pathogenic	0.966
OPA1	O60313-1.3	M322R	Pathogenic	0.974
OPA1	O60313-1.3	M322S	Pathogenic	0.988
OPA1	O60313-1.3	M322T	Pathogenic	0.992
OPA1	O60313-1.3	M322V	Pathogenic	0.972
OPA1	O60313-1.3	M322W	Pathogenic	0.991
OPA1	O60313-1.3	M322Y	Pathogenic	0.996
OPA1	O60313-1.3	T323A	Pathogenic	0.985
OPA1	O60313-1.3	T323C	Pathogenic	0.991
OPA1	O60313-1.3	T323D	Pathogenic	0.989
OPA1	O60313-1.3	T323E	Pathogenic	0.99
OPA1	O60313-1.3	T323F	Pathogenic	0.993
OPA1	O60313-1.3	T323G	Pathogenic	0.998
OPA1	O60313-1.3	T323H	Pathogenic	0.998
OPA1	O60313-1.3	T323I	Pathogenic	0.98
OPA1	O60313-1.3	T323K	Pathogenic	0.984
OPA1	O60313-1.3	T323L	Pathogenic	0.982
OPA1	O60313-1.3	T323M	Pathogenic	0.988
OPA1	O60313-1.3	T323N	Pathogenic	0.972
OPA1	O60313-1.3	T323P	Pathogenic	0.993
OPA1	O60313-1.3	T323Q	Pathogenic	0.993
OPA1	O60313-1.3	T323R	Pathogenic	0.983
OPA1	O60313-1.3	T323S	Pathogenic	0.95
OPA1	O60313-1.3	T323V	Pathogenic	0.969
OPA1	O60313-1.3	T323W	Pathogenic	0.988
OPA1	O60313-1.3	T323Y	Pathogenic	0.997
OPA1	O60313-1.3	R324A	Pathogenic	0.979
OPA1	O60313-1.3	R324C	Pathogenic	0.996
OPA1	O60313-1.3	R324D	Pathogenic	0.997
OPA1	O60313-1.3	R324E	Pathogenic	0.978
OPA1	O60313-1.3	R324F	Pathogenic	0.992
OPA1	O60313-1.3	R324G	Pathogenic	0.994
OPA1	O60313-1.3	R324H	Pathogenic	0.958
OPA1	O60313-1.3	R324I	Pathogenic	0.992
OPA1	O60313-1.3	R324K	Pathogenic	0.89
OPA1	O60313-1.3	R324L	Pathogenic	0.979
OPA1	O60313-1.3	R324M	Pathogenic	0.961
OPA1	O60313-1.3	R324N	Pathogenic	0.976
OPA1	O60313-1.3	R324P	Pathogenic	0.99
OPA1	O60313-1.3	R324Q	Pathogenic	0.914
OPA1	O60313-1.3	R324S	Pathogenic	0.985
OPA1	O60313-1.3	R324T	Pathogenic	0.982
OPA1	O60313-1.3	R324V	Pathogenic	0.995
OPA1	O60313-1.3	R324W	Pathogenic	0.988
OPA1	O60313-1.3	R324Y	Pathogenic	0.99
OPA1	O60313-1.3	S325A	Neutral	0.482
OPA1	O60313-1.3	S325C	Pathogenic	0.804
OPA1	O60313-1.3	S325D	Pathogenic	0.644
OPA1	O60313-1.3	S325E	Pathogenic	0.656
OPA1	O60313-1.3	S325F	Pathogenic	0.826
OPA1	O60313-1.3	S325G	Pathogenic	0.769
OPA1	O60313-1.3	S325H	Pathogenic	0.888
OPA1	O60313-1.3	S325I	Pathogenic	0.83
OPA1	O60313-1.3	S325K	Pathogenic	0.556
OPA1	O60313-1.3	S325L	Pathogenic	0.843
OPA1	O60313-1.3	S325M	Pathogenic	0.739
OPA1	O60313-1.3	S325N	Neutral	0.416
OPA1	O60313-1.3	S325P	Pathogenic	0.837
OPA1	O60313-1.3	S325Q	Pathogenic	0.733
OPA1	O60313-1.3	S325R	Pathogenic	0.773
OPA1	O60313-1.3	S325T	Neutral	0.48
OPA1	O60313-1.3	S325V	Pathogenic	0.899
OPA1	O60313-1.3	S325W	Pathogenic	0.89
OPA1	O60313-1.3	S325Y	Pathogenic	0.908
OPA1	O60313-1.3	P326A	Pathogenic	0.994
OPA1	O60313-1.3	P326C	Pathogenic	0.999
OPA1	O60313-1.3	P326D	Pathogenic	0.986
OPA1	O60313-1.3	P326E	Pathogenic	0.987
OPA1	O60313-1.3	P326F	Pathogenic	1.0
OPA1	O60313-1.3	P326G	Pathogenic	0.997
OPA1	O60313-1.3	P326H	Pathogenic	0.998
OPA1	O60313-1.3	P326I	Pathogenic	0.999
OPA1	O60313-1.3	P326K	Pathogenic	0.98
OPA1	O60313-1.3	P326L	Pathogenic	0.999
OPA1	O60313-1.3	P326M	Pathogenic	0.998
OPA1	O60313-1.3	P326N	Pathogenic	0.996
OPA1	O60313-1.3	P326Q	Pathogenic	0.991
OPA1	O60313-1.3	P326R	Pathogenic	0.993
OPA1	O60313-1.3	P326S	Pathogenic	0.992
OPA1	O60313-1.3	P326T	Pathogenic	0.994
OPA1	O60313-1.3	P326V	Pathogenic	0.998
OPA1	O60313-1.3	P326W	Pathogenic	0.999
OPA1	O60313-1.3	P326Y	Pathogenic	0.999
OPA1	O60313-1.3	V327A	Pathogenic	0.965
OPA1	O60313-1.3	V327C	Pathogenic	0.994
OPA1	O60313-1.3	V327D	Pathogenic	0.996
OPA1	O60313-1.3	V327E	Pathogenic	0.991
OPA1	O60313-1.3	V327F	Pathogenic	0.991
OPA1	O60313-1.3	V327G	Pathogenic	0.998
OPA1	O60313-1.3	V327H	Pathogenic	0.998
OPA1	O60313-1.3	V327I	Pathogenic	0.617
OPA1	O60313-1.3	V327K	Pathogenic	0.986
OPA1	O60313-1.3	V327L	Pathogenic	0.937
OPA1	O60313-1.3	V327M	Pathogenic	0.958
OPA1	O60313-1.3	V327N	Pathogenic	0.997
OPA1	O60313-1.3	V327P	Pathogenic	0.997
OPA1	O60313-1.3	V327Q	Pathogenic	0.994
OPA1	O60313-1.3	V327R	Pathogenic	0.995
OPA1	O60313-1.3	V327S	Pathogenic	0.994
OPA1	O60313-1.3	V327T	Pathogenic	0.966
OPA1	O60313-1.3	V327W	Pathogenic	0.998
OPA1	O60313-1.3	V327Y	Pathogenic	0.993
OPA1	O60313-1.3	K328A	Pathogenic	0.973
OPA1	O60313-1.3	K328C	Pathogenic	0.994
OPA1	O60313-1.3	K328D	Pathogenic	0.991
OPA1	O60313-1.3	K328E	Pathogenic	0.923
OPA1	O60313-1.3	K328F	Pathogenic	0.99
OPA1	O60313-1.3	K328G	Pathogenic	0.992
OPA1	O60313-1.3	K328H	Pathogenic	0.981
OPA1	O60313-1.3	K328I	Pathogenic	0.99
OPA1	O60313-1.3	K328L	Pathogenic	0.973
OPA1	O60313-1.3	K328M	Pathogenic	0.95
OPA1	O60313-1.3	K328N	Pathogenic	0.97
OPA1	O60313-1.3	K328P	Pathogenic	0.964
OPA1	O60313-1.3	K328Q	Pathogenic	0.892
OPA1	O60313-1.3	K328R	Pathogenic	0.854
OPA1	O60313-1.3	K328S	Pathogenic	0.946
OPA1	O60313-1.3	K328T	Pathogenic	0.977
OPA1	O60313-1.3	K328V	Pathogenic	0.981
OPA1	O60313-1.3	K328W	Pathogenic	0.983
OPA1	O60313-1.3	K328Y	Pathogenic	0.986
OPA1	O60313-1.3	V329A	Pathogenic	0.965
OPA1	O60313-1.3	V329C	Pathogenic	0.994
OPA1	O60313-1.3	V329D	Pathogenic	0.996
OPA1	O60313-1.3	V329E	Pathogenic	0.991
OPA1	O60313-1.3	V329F	Pathogenic	0.991
OPA1	O60313-1.3	V329G	Pathogenic	0.998
OPA1	O60313-1.3	V329H	Pathogenic	0.998
OPA1	O60313-1.3	V329I	Pathogenic	0.617
OPA1	O60313-1.3	V329K	Pathogenic	0.986
OPA1	O60313-1.3	V329L	Pathogenic	0.937
OPA1	O60313-1.3	V329M	Pathogenic	0.958
OPA1	O60313-1.3	V329N	Pathogenic	0.997
OPA1	O60313-1.3	V329P	Pathogenic	0.997
OPA1	O60313-1.3	V329Q	Pathogenic	0.994
OPA1	O60313-1.3	V329R	Pathogenic	0.995
OPA1	O60313-1.3	V329S	Pathogenic	0.994
OPA1	O60313-1.3	V329T	Pathogenic	0.966
OPA1	O60313-1.3	V329W	Pathogenic	0.998
OPA1	O60313-1.3	V329Y	Pathogenic	0.993
OPA1	O60313-1.3	T330A	Pathogenic	0.985
OPA1	O60313-1.3	T330C	Pathogenic	0.991
OPA1	O60313-1.3	T330D	Pathogenic	0.989
OPA1	O60313-1.3	T330E	Pathogenic	0.99
OPA1	O60313-1.3	T330F	Pathogenic	0.993
OPA1	O60313-1.3	T330G	Pathogenic	0.998
OPA1	O60313-1.3	T330H	Pathogenic	0.998
OPA1	O60313-1.3	T330I	Pathogenic	0.98
OPA1	O60313-1.3	T330K	Pathogenic	0.984
OPA1	O60313-1.3	T330L	Pathogenic	0.982
OPA1	O60313-1.3	T330M	Pathogenic	0.988
OPA1	O60313-1.3	T330N	Pathogenic	0.972
OPA1	O60313-1.3	T330P	Pathogenic	0.993
OPA1	O60313-1.3	T330Q	Pathogenic	0.993
OPA1	O60313-1.3	T330R	Pathogenic	0.983
OPA1	O60313-1.3	T330S	Pathogenic	0.95
OPA1	O60313-1.3	T330V	Pathogenic	0.969
OPA1	O60313-1.3	T330W	Pathogenic	0.988
OPA1	O60313-1.3	T330Y	Pathogenic	0.997
OPA1	O60313-1.3	L331A	Pathogenic	0.982
OPA1	O60313-1.3	L331C	Pathogenic	0.991
OPA1	O60313-1.3	L331D	Pathogenic	0.998
OPA1	O60313-1.3	L331E	Pathogenic	0.996
OPA1	O60313-1.3	L331F	Pathogenic	0.987
OPA1	O60313-1.3	L331G	Pathogenic	0.999
OPA1	O60313-1.3	L331H	Pathogenic	0.998
OPA1	O60313-1.3	L331I	Pathogenic	0.902
OPA1	O60313-1.3	L331K	Pathogenic	0.983
OPA1	O60313-1.3	L331M	Pathogenic	0.868
OPA1	O60313-1.3	L331N	Pathogenic	0.996
OPA1	O60313-1.3	L331P	Pathogenic	0.999
OPA1	O60313-1.3	L331Q	Pathogenic	0.992
OPA1	O60313-1.3	L331R	Pathogenic	0.982
OPA1	O60313-1.3	L331S	Pathogenic	0.992
OPA1	O60313-1.3	L331T	Pathogenic	0.983
OPA1	O60313-1.3	L331V	Pathogenic	0.946
OPA1	O60313-1.3	L331W	Pathogenic	0.997
OPA1	O60313-1.3	L331Y	Pathogenic	0.992
OPA1	O60313-1.3	S332A	Pathogenic	0.914
OPA1	O60313-1.3	S332C	Pathogenic	0.979
OPA1	O60313-1.3	S332D	Pathogenic	0.954
OPA1	O60313-1.3	S332E	Pathogenic	0.956
OPA1	O60313-1.3	S332F	Pathogenic	0.982
OPA1	O60313-1.3	S332G	Pathogenic	0.974
OPA1	O60313-1.3	S332H	Pathogenic	0.989
OPA1	O60313-1.3	S332I	Pathogenic	0.982
OPA1	O60313-1.3	S332K	Pathogenic	0.935
OPA1	O60313-1.3	S332L	Pathogenic	0.984
OPA1	O60313-1.3	S332M	Pathogenic	0.97
OPA1	O60313-1.3	S332N	Pathogenic	0.891
OPA1	O60313-1.3	S332P	Pathogenic	0.983
OPA1	O60313-1.3	S332Q	Pathogenic	0.969
OPA1	O60313-1.3	S332R	Pathogenic	0.975
OPA1	O60313-1.3	S332T	Pathogenic	0.914
OPA1	O60313-1.3	S332V	Pathogenic	0.99
OPA1	O60313-1.3	S332W	Pathogenic	0.989
OPA1	O60313-1.3	S332Y	Pathogenic	0.991
OPA1	O60313-1.3	E333A	Pathogenic	0.99
OPA1	O60313-1.3	E333C	Pathogenic	0.999
OPA1	O60313-1.3	E333D	Pathogenic	0.9
OPA1	O60313-1.3	E333F	Pathogenic	0.995
OPA1	O60313-1.3	E333G	Pathogenic	0.997
OPA1	O60313-1.3	E333H	Pathogenic	0.978
OPA1	O60313-1.3	E333I	Pathogenic	0.996
OPA1	O60313-1.3	E333K	Pathogenic	0.954
OPA1	O60313-1.3	E333L	Pathogenic	0.996
OPA1	O60313-1.3	E333M	Pathogenic	0.992
OPA1	O60313-1.3	E333N	Pathogenic	0.988
OPA1	O60313-1.3	E333P	Pathogenic	0.986
OPA1	O60313-1.3	E333Q	Pathogenic	0.88
OPA1	O60313-1.3	E333R	Pathogenic	0.983
OPA1	O60313-1.3	E333S	Pathogenic	0.979
OPA1	O60313-1.3	E333T	Pathogenic	0.991
OPA1	O60313-1.3	E333V	Pathogenic	0.993
OPA1	O60313-1.3	E333W	Pathogenic	0.992
OPA1	O60313-1.3	E333Y	Pathogenic	0.994
OPA1	O60313-1.3	G334A	Pathogenic	0.989
OPA1	O60313-1.3	G334C	Pathogenic	0.999
OPA1	O60313-1.3	G334D	Pathogenic	0.994
OPA1	O60313-1.3	G334E	Pathogenic	0.998
OPA1	O60313-1.3	G334F	Pathogenic	0.998
OPA1	O60313-1.3	G334H	Pathogenic	0.999
OPA1	O60313-1.3	G334I	Pathogenic	0.999
OPA1	O60313-1.3	G334K	Pathogenic	0.997
OPA1	O60313-1.3	G334L	Pathogenic	0.999
OPA1	O60313-1.3	G334M	Pathogenic	0.999
OPA1	O60313-1.3	G334N	Pathogenic	0.984
OPA1	O60313-1.3	G334P	Pathogenic	0.998
OPA1	O60313-1.3	G334Q	Pathogenic	0.999
OPA1	O60313-1.3	G334R	Pathogenic	0.997
OPA1	O60313-1.3	G334S	Pathogenic	0.991
OPA1	O60313-1.3	G334T	Pathogenic	0.999
OPA1	O60313-1.3	G334V	Pathogenic	0.999
OPA1	O60313-1.3	G334W	Pathogenic	0.989
OPA1	O60313-1.3	G334Y	Pathogenic	0.999
OPA1	O60313-1.3	P335A	Pathogenic	0.996
OPA1	O60313-1.3	P335C	Pathogenic	1.0
OPA1	O60313-1.3	P335D	Pathogenic	0.99
OPA1	O60313-1.3	P335E	Pathogenic	0.991
OPA1	O60313-1.3	P335F	Pathogenic	1.0
OPA1	O60313-1.3	P335G	Pathogenic	0.998
OPA1	O60313-1.3	P335H	Pathogenic	0.998
OPA1	O60313-1.3	P335I	Pathogenic	0.999
OPA1	O60313-1.3	P335K	Pathogenic	0.986
OPA1	O60313-1.3	P335L	Pathogenic	0.999
OPA1	O60313-1.3	P335M	Pathogenic	0.998
OPA1	O60313-1.3	P335N	Pathogenic	0.997
OPA1	O60313-1.3	P335Q	Pathogenic	0.994
OPA1	O60313-1.3	P335R	Pathogenic	0.995
OPA1	O60313-1.3	P335S	Pathogenic	0.995
OPA1	O60313-1.3	P335T	Pathogenic	0.996
OPA1	O60313-1.3	P335V	Pathogenic	0.999
OPA1	O60313-1.3	P335W	Pathogenic	0.999
OPA1	O60313-1.3	P335Y	Pathogenic	1.0
OPA1	O60313-1.3	H336A	Pathogenic	0.983
OPA1	O60313-1.3	H336C	Pathogenic	0.99
OPA1	O60313-1.3	H336D	Pathogenic	0.919
OPA1	O60313-1.3	H336E	Pathogenic	0.826
OPA1	O60313-1.3	H336F	Pathogenic	0.856
OPA1	O60313-1.3	H336G	Pathogenic	0.983
OPA1	O60313-1.3	H336I	Pathogenic	0.981
OPA1	O60313-1.3	H336K	Pathogenic	0.906
OPA1	O60313-1.3	H336L	Pathogenic	0.983
OPA1	O60313-1.3	H336M	Pathogenic	0.968
OPA1	O60313-1.3	H336N	Pathogenic	0.617
OPA1	O60313-1.3	H336P	Pathogenic	0.978
OPA1	O60313-1.3	H336Q	Pathogenic	0.876
OPA1	O60313-1.3	H336R	Pathogenic	0.758
OPA1	O60313-1.3	H336S	Pathogenic	0.954
OPA1	O60313-1.3	H336T	Pathogenic	0.985
OPA1	O60313-1.3	H336V	Pathogenic	0.988
OPA1	O60313-1.3	H336W	Pathogenic	0.91
OPA1	O60313-1.3	H336Y	Neutral	0.337
OPA1	O60313-1.3	H337A	Pathogenic	0.999
OPA1	O60313-1.3	H337C	Pathogenic	0.999
OPA1	O60313-1.3	H337D	Pathogenic	0.994
OPA1	O60313-1.3	H337E	Pathogenic	0.986
OPA1	O60313-1.3	H337F	Pathogenic	0.989
OPA1	O60313-1.3	H337G	Pathogenic	0.999
OPA1	O60313-1.3	H337I	Pathogenic	0.999
OPA1	O60313-1.3	H337K	Pathogenic	0.993
OPA1	O60313-1.3	H337L	Pathogenic	0.999
OPA1	O60313-1.3	H337M	Pathogenic	0.998
OPA1	O60313-1.3	H337N	Pathogenic	0.961
OPA1	O60313-1.3	H337P	Pathogenic	0.998
OPA1	O60313-1.3	H337Q	Pathogenic	0.991
OPA1	O60313-1.3	H337R	Pathogenic	0.979
OPA1	O60313-1.3	H337S	Pathogenic	0.997
OPA1	O60313-1.3	H337T	Pathogenic	0.999
OPA1	O60313-1.3	H337V	Pathogenic	0.999
OPA1	O60313-1.3	H337W	Pathogenic	0.994
OPA1	O60313-1.3	H337Y	Pathogenic	0.885
OPA1	O60313-1.3	V338A	Pathogenic	0.784
OPA1	O60313-1.3	V338C	Pathogenic	0.954
OPA1	O60313-1.3	V338D	Pathogenic	0.973
OPA1	O60313-1.3	V338E	Pathogenic	0.936
OPA1	O60313-1.3	V338F	Pathogenic	0.936
OPA1	O60313-1.3	V338G	Pathogenic	0.984
OPA1	O60313-1.3	V338H	Pathogenic	0.988
OPA1	O60313-1.3	V338I	Neutral	0.176
OPA1	O60313-1.3	V338K	Pathogenic	0.905
OPA1	O60313-1.3	V338L	Pathogenic	0.664
OPA1	O60313-1.3	V338M	Pathogenic	0.752
OPA1	O60313-1.3	V338N	Pathogenic	0.977
OPA1	O60313-1.3	V338P	Pathogenic	0.98
OPA1	O60313-1.3	V338Q	Pathogenic	0.954
OPA1	O60313-1.3	V338R	Pathogenic	0.963
OPA1	O60313-1.3	V338S	Pathogenic	0.958
OPA1	O60313-1.3	V338T	Pathogenic	0.792
OPA1	O60313-1.3	V338W	Pathogenic	0.986
OPA1	O60313-1.3	V338Y	Pathogenic	0.951
OPA1	O60313-1.3	A339C	Pathogenic	0.982
OPA1	O60313-1.3	A339D	Pathogenic	0.997
OPA1	O60313-1.3	A339E	Pathogenic	0.991
OPA1	O60313-1.3	A339F	Pathogenic	0.995
OPA1	O60313-1.3	A339G	Pathogenic	0.987
OPA1	O60313-1.3	A339H	Pathogenic	0.998
OPA1	O60313-1.3	A339I	Pathogenic	0.985
OPA1	O60313-1.3	A339K	Pathogenic	0.987
OPA1	O60313-1.3	A339L	Pathogenic	0.986
OPA1	O60313-1.3	A339M	Pathogenic	0.991
OPA1	O60313-1.3	A339N	Pathogenic	0.997
OPA1	O60313-1.3	A339P	Pathogenic	0.995
OPA1	O60313-1.3	A339Q	Pathogenic	0.994
OPA1	O60313-1.3	A339R	Pathogenic	0.986
OPA1	O60313-1.3	A339S	Pathogenic	0.964
OPA1	O60313-1.3	A339T	Pathogenic	0.99
OPA1	O60313-1.3	A339V	Pathogenic	0.976
OPA1	O60313-1.3	A339W	Pathogenic	0.997
OPA1	O60313-1.3	A339Y	Pathogenic	0.997
OPA1	O60313-1.3	L340A	Neutral	0.063
OPA1	O60313-1.3	L340C	Neutral	0.118
OPA1	O60313-1.3	L340D	Neutral	0.402
OPA1	O60313-1.3	L340E	Neutral	0.218
OPA1	O60313-1.3	L340F	Neutral	0.084
OPA1	O60313-1.3	L340G	Pathogenic	0.536
OPA1	O60313-1.3	L340H	Neutral	0.369
OPA1	O60313-1.3	L340I	Neutral	0.011
OPA1	O60313-1.3	L340K	Neutral	0.066
OPA1	O60313-1.3	L340M	Neutral	0.008
OPA1	O60313-1.3	L340N	Neutral	0.216
OPA1	O60313-1.3	L340P	Neutral	0.474
OPA1	O60313-1.3	L340Q	Neutral	0.126
OPA1	O60313-1.3	L340R	Neutral	0.062
OPA1	O60313-1.3	L340S	Neutral	0.127
OPA1	O60313-1.3	L340T	Neutral	0.066
OPA1	O60313-1.3	L340V	Neutral	0.021
OPA1	O60313-1.3	L340W	Neutral	0.312
OPA1	O60313-1.3	L340Y	Neutral	0.125
OPA1	O60313-1.3	F341A	Pathogenic	0.996
OPA1	O60313-1.3	F341C	Pathogenic	0.998
OPA1	O60313-1.3	F341D	Pathogenic	0.996
OPA1	O60313-1.3	F341E	Pathogenic	0.997
OPA1	O60313-1.3	F341G	Pathogenic	0.998
OPA1	O60313-1.3	F341H	Pathogenic	0.988
OPA1	O60313-1.3	F341I	Pathogenic	0.992
OPA1	O60313-1.3	F341K	Pathogenic	0.996
OPA1	O60313-1.3	F341L	Pathogenic	0.992
OPA1	O60313-1.3	F341M	Pathogenic	0.987
OPA1	O60313-1.3	F341N	Pathogenic	0.997
OPA1	O60313-1.3	F341P	Pathogenic	1.0
OPA1	O60313-1.3	F341Q	Pathogenic	0.998
OPA1	O60313-1.3	F341R	Pathogenic	0.996
OPA1	O60313-1.3	F341S	Pathogenic	0.994
OPA1	O60313-1.3	F341T	Pathogenic	0.996
OPA1	O60313-1.3	F341V	Pathogenic	0.995
OPA1	O60313-1.3	F341W	Pathogenic	0.965
OPA1	O60313-1.3	F341Y	Pathogenic	0.718
OPA1	O60313-1.3	K342A	Pathogenic	0.964
OPA1	O60313-1.3	K342C	Pathogenic	0.992
OPA1	O60313-1.3	K342D	Pathogenic	0.987
OPA1	O60313-1.3	K342E	Pathogenic	0.899
OPA1	O60313-1.3	K342F	Pathogenic	0.987
OPA1	O60313-1.3	K342G	Pathogenic	0.99
OPA1	O60313-1.3	K342H	Pathogenic	0.974
OPA1	O60313-1.3	K342I	Pathogenic	0.986
OPA1	O60313-1.3	K342L	Pathogenic	0.964
OPA1	O60313-1.3	K342M	Pathogenic	0.934
OPA1	O60313-1.3	K342N	Pathogenic	0.959
OPA1	O60313-1.3	K342P	Pathogenic	0.952
OPA1	O60313-1.3	K342Q	Pathogenic	0.86
OPA1	O60313-1.3	K342R	Pathogenic	0.814
OPA1	O60313-1.3	K342S	Pathogenic	0.928
OPA1	O60313-1.3	K342T	Pathogenic	0.969
OPA1	O60313-1.3	K342V	Pathogenic	0.975
OPA1	O60313-1.3	K342W	Pathogenic	0.978
OPA1	O60313-1.3	K342Y	Pathogenic	0.982
OPA1	O60313-1.3	D343A	Pathogenic	0.997
OPA1	O60313-1.3	D343C	Pathogenic	0.998
OPA1	O60313-1.3	D343E	Pathogenic	0.914
OPA1	O60313-1.3	D343F	Pathogenic	0.995
OPA1	O60313-1.3	D343G	Pathogenic	0.992
OPA1	O60313-1.3	D343H	Pathogenic	0.992
OPA1	O60313-1.3	D343I	Pathogenic	0.995
OPA1	O60313-1.3	D343K	Pathogenic	0.995
OPA1	O60313-1.3	D343L	Pathogenic	0.999
OPA1	O60313-1.3	D343M	Pathogenic	0.997
OPA1	O60313-1.3	D343N	Pathogenic	0.969
OPA1	O60313-1.3	D343P	Pathogenic	0.988
OPA1	O60313-1.3	D343Q	Pathogenic	0.983
OPA1	O60313-1.3	D343R	Pathogenic	0.998
OPA1	O60313-1.3	D343S	Pathogenic	0.981
OPA1	O60313-1.3	D343T	Pathogenic	0.992
OPA1	O60313-1.3	D343V	Pathogenic	0.998
OPA1	O60313-1.3	D343W	Pathogenic	0.997
OPA1	O60313-1.3	D343Y	Pathogenic	0.998
OPA1	O60313-1.3	S344A	Pathogenic	0.962
OPA1	O60313-1.3	S344C	Pathogenic	0.991
OPA1	O60313-1.3	S344D	Pathogenic	0.98
OPA1	O60313-1.3	S344E	Pathogenic	0.981
OPA1	O60313-1.3	S344F	Pathogenic	0.992
OPA1	O60313-1.3	S344G	Pathogenic	0.989
OPA1	O60313-1.3	S344H	Pathogenic	0.995
OPA1	O60313-1.3	S344I	Pathogenic	0.993
OPA1	O60313-1.3	S344K	Pathogenic	0.972
OPA1	O60313-1.3	S344L	Pathogenic	0.993
OPA1	O60313-1.3	S344M	Pathogenic	0.987
OPA1	O60313-1.3	S344N	Pathogenic	0.951
OPA1	O60313-1.3	S344P	Pathogenic	0.993
OPA1	O60313-1.3	S344Q	Pathogenic	0.987
OPA1	O60313-1.3	S344R	Pathogenic	0.989
OPA1	O60313-1.3	S344T	Pathogenic	0.962
OPA1	O60313-1.3	S344V	Pathogenic	0.996
OPA1	O60313-1.3	S344W	Pathogenic	0.996
OPA1	O60313-1.3	S344Y	Pathogenic	0.996
OPA1	O60313-1.3	S345A	Pathogenic	0.536
OPA1	O60313-1.3	S345C	Pathogenic	0.836
OPA1	O60313-1.3	S345D	Pathogenic	0.692
OPA1	O60313-1.3	S345E	Pathogenic	0.703
OPA1	O60313-1.3	S345F	Pathogenic	0.855
OPA1	O60313-1.3	S345G	Pathogenic	0.805
OPA1	O60313-1.3	S345H	Pathogenic	0.908
OPA1	O60313-1.3	S345I	Pathogenic	0.858
OPA1	O60313-1.3	S345K	Pathogenic	0.609
OPA1	O60313-1.3	S345L	Pathogenic	0.869
OPA1	O60313-1.3	S345M	Pathogenic	0.779
OPA1	O60313-1.3	S345N	Neutral	0.47
OPA1	O60313-1.3	S345P	Pathogenic	0.865
OPA1	O60313-1.3	S345Q	Pathogenic	0.773
OPA1	O60313-1.3	S345R	Pathogenic	0.809
OPA1	O60313-1.3	S345T	Pathogenic	0.535
OPA1	O60313-1.3	S345V	Pathogenic	0.918
OPA1	O60313-1.3	S345W	Pathogenic	0.91
OPA1	O60313-1.3	S345Y	Pathogenic	0.925
OPA1	O60313-1.3	R346A	Pathogenic	0.985
OPA1	O60313-1.3	R346C	Pathogenic	0.997
OPA1	O60313-1.3	R346D	Pathogenic	0.998
OPA1	O60313-1.3	R346E	Pathogenic	0.985
OPA1	O60313-1.3	R346F	Pathogenic	0.995
OPA1	O60313-1.3	R346G	Pathogenic	0.996
OPA1	O60313-1.3	R346H	Pathogenic	0.97
OPA1	O60313-1.3	R346I	Pathogenic	0.994
OPA1	O60313-1.3	R346K	Pathogenic	0.921
OPA1	O60313-1.3	R346L	Pathogenic	0.985
OPA1	O60313-1.3	R346M	Pathogenic	0.973
OPA1	O60313-1.3	R346N	Pathogenic	0.983
OPA1	O60313-1.3	R346P	Pathogenic	0.993
OPA1	O60313-1.3	R346Q	Pathogenic	0.939
OPA1	O60313-1.3	R346S	Pathogenic	0.989
OPA1	O60313-1.3	R346T	Pathogenic	0.987
OPA1	O60313-1.3	R346V	Pathogenic	0.996
OPA1	O60313-1.3	R346W	Pathogenic	0.992
OPA1	O60313-1.3	R346Y	Pathogenic	0.993
OPA1	O60313-1.3	E347A	Pathogenic	0.988
OPA1	O60313-1.3	E347C	Pathogenic	0.999
OPA1	O60313-1.3	E347D	Pathogenic	0.888
OPA1	O60313-1.3	E347F	Pathogenic	0.995
OPA1	O60313-1.3	E347G	Pathogenic	0.997
OPA1	O60313-1.3	E347H	Pathogenic	0.975
OPA1	O60313-1.3	E347I	Pathogenic	0.995
OPA1	O60313-1.3	E347K	Pathogenic	0.948
OPA1	O60313-1.3	E347L	Pathogenic	0.995
OPA1	O60313-1.3	E347M	Pathogenic	0.991
OPA1	O60313-1.3	E347N	Pathogenic	0.987
OPA1	O60313-1.3	E347P	Pathogenic	0.984
OPA1	O60313-1.3	E347Q	Pathogenic	0.865
OPA1	O60313-1.3	E347R	Pathogenic	0.98
OPA1	O60313-1.3	E347S	Pathogenic	0.976
OPA1	O60313-1.3	E347T	Pathogenic	0.99
OPA1	O60313-1.3	E347V	Pathogenic	0.992
OPA1	O60313-1.3	E347W	Pathogenic	0.991
OPA1	O60313-1.3	E347Y	Pathogenic	0.993
OPA1	O60313-1.3	F348A	Pathogenic	0.99
OPA1	O60313-1.3	F348C	Pathogenic	0.995
OPA1	O60313-1.3	F348D	Pathogenic	0.991
OPA1	O60313-1.3	F348E	Pathogenic	0.993
OPA1	O60313-1.3	F348G	Pathogenic	0.995
OPA1	O60313-1.3	F348H	Pathogenic	0.971
OPA1	O60313-1.3	F348I	Pathogenic	0.982
OPA1	O60313-1.3	F348K	Pathogenic	0.991
OPA1	O60313-1.3	F348L	Pathogenic	0.98
OPA1	O60313-1.3	F348M	Pathogenic	0.97
OPA1	O60313-1.3	F348N	Pathogenic	0.993
OPA1	O60313-1.3	F348P	Pathogenic	0.999
OPA1	O60313-1.3	F348Q	Pathogenic	0.995
OPA1	O60313-1.3	F348R	Pathogenic	0.99
OPA1	O60313-1.3	F348S	Pathogenic	0.986
OPA1	O60313-1.3	F348T	Pathogenic	0.99
OPA1	O60313-1.3	F348V	Pathogenic	0.989
OPA1	O60313-1.3	F348W	Pathogenic	0.92
OPA1	O60313-1.3	F348Y	Pathogenic	0.516
OPA1	O60313-1.3	D349A	Pathogenic	0.997
OPA1	O60313-1.3	D349C	Pathogenic	0.998
OPA1	O60313-1.3	D349E	Pathogenic	0.914
OPA1	O60313-1.3	D349F	Pathogenic	0.995
OPA1	O60313-1.3	D349G	Pathogenic	0.992
OPA1	O60313-1.3	D349H	Pathogenic	0.992
OPA1	O60313-1.3	D349I	Pathogenic	0.995
OPA1	O60313-1.3	D349K	Pathogenic	0.995
OPA1	O60313-1.3	D349L	Pathogenic	0.999
OPA1	O60313-1.3	D349M	Pathogenic	0.997
OPA1	O60313-1.3	D349N	Pathogenic	0.969
OPA1	O60313-1.3	D349P	Pathogenic	0.988
OPA1	O60313-1.3	D349Q	Pathogenic	0.983
OPA1	O60313-1.3	D349R	Pathogenic	0.998
OPA1	O60313-1.3	D349S	Pathogenic	0.981
OPA1	O60313-1.3	D349T	Pathogenic	0.992
OPA1	O60313-1.3	D349V	Pathogenic	0.998
OPA1	O60313-1.3	D349W	Pathogenic	0.997
OPA1	O60313-1.3	D349Y	Pathogenic	0.998
OPA1	O60313-1.3	L350A	Pathogenic	0.982
OPA1	O60313-1.3	L350C	Pathogenic	0.991
OPA1	O60313-1.3	L350D	Pathogenic	0.998
OPA1	O60313-1.3	L350E	Pathogenic	0.996
OPA1	O60313-1.3	L350F	Pathogenic	0.987
OPA1	O60313-1.3	L350G	Pathogenic	0.999
OPA1	O60313-1.3	L350H	Pathogenic	0.998
OPA1	O60313-1.3	L350I	Pathogenic	0.902
OPA1	O60313-1.3	L350K	Pathogenic	0.983
OPA1	O60313-1.3	L350M	Pathogenic	0.868
OPA1	O60313-1.3	L350N	Pathogenic	0.996
OPA1	O60313-1.3	L350P	Pathogenic	0.999
OPA1	O60313-1.3	L350Q	Pathogenic	0.992
OPA1	O60313-1.3	L350R	Pathogenic	0.982
OPA1	O60313-1.3	L350S	Pathogenic	0.992
OPA1	O60313-1.3	L350T	Pathogenic	0.983
OPA1	O60313-1.3	L350V	Pathogenic	0.946
OPA1	O60313-1.3	L350W	Pathogenic	0.997
OPA1	O60313-1.3	L350Y	Pathogenic	0.992
OPA1	O60313-1.3	T351A	Pathogenic	0.902
OPA1	O60313-1.3	T351C	Pathogenic	0.939
OPA1	O60313-1.3	T351D	Pathogenic	0.923
OPA1	O60313-1.3	T351E	Pathogenic	0.928
OPA1	O60313-1.3	T351F	Pathogenic	0.949
OPA1	O60313-1.3	T351G	Pathogenic	0.984
OPA1	O60313-1.3	T351H	Pathogenic	0.986
OPA1	O60313-1.3	T351I	Pathogenic	0.869
OPA1	O60313-1.3	T351K	Pathogenic	0.894
OPA1	O60313-1.3	T351L	Pathogenic	0.88
OPA1	O60313-1.3	T351M	Pathogenic	0.918
OPA1	O60313-1.3	T351N	Pathogenic	0.827
OPA1	O60313-1.3	T351P	Pathogenic	0.952
OPA1	O60313-1.3	T351Q	Pathogenic	0.948
OPA1	O60313-1.3	T351R	Pathogenic	0.888
OPA1	O60313-1.3	T351S	Pathogenic	0.722
OPA1	O60313-1.3	T351V	Pathogenic	0.808
OPA1	O60313-1.3	T351W	Pathogenic	0.917
OPA1	O60313-1.3	T351Y	Pathogenic	0.975
OPA1	O60313-1.3	K352A	Pathogenic	0.985
OPA1	O60313-1.3	K352C	Pathogenic	0.997
OPA1	O60313-1.3	K352D	Pathogenic	0.995
OPA1	O60313-1.3	K352E	Pathogenic	0.955
OPA1	O60313-1.3	K352F	Pathogenic	0.994
OPA1	O60313-1.3	K352G	Pathogenic	0.996
OPA1	O60313-1.3	K352H	Pathogenic	0.989
OPA1	O60313-1.3	K352I	Pathogenic	0.994
OPA1	O60313-1.3	K352L	Pathogenic	0.985
OPA1	O60313-1.3	K352M	Pathogenic	0.971
OPA1	O60313-1.3	K352N	Pathogenic	0.983
OPA1	O60313-1.3	K352P	Pathogenic	0.98
OPA1	O60313-1.3	K352Q	Pathogenic	0.936
OPA1	O60313-1.3	K352R	Pathogenic	0.912
OPA1	O60313-1.3	K352S	Pathogenic	0.969
OPA1	O60313-1.3	K352T	Pathogenic	0.987
OPA1	O60313-1.3	K352V	Pathogenic	0.989
OPA1	O60313-1.3	K352W	Pathogenic	0.991
OPA1	O60313-1.3	K352Y	Pathogenic	0.992
OPA1	O60313-1.3	E353A	Pathogenic	0.984
OPA1	O60313-1.3	E353C	Pathogenic	0.999
OPA1	O60313-1.3	E353D	Pathogenic	0.851
OPA1	O60313-1.3	E353F	Pathogenic	0.993
OPA1	O60313-1.3	E353G	Pathogenic	0.995
OPA1	O60313-1.3	E353H	Pathogenic	0.965
OPA1	O60313-1.3	E353I	Pathogenic	0.993
OPA1	O60313-1.3	E353K	Pathogenic	0.929
OPA1	O60313-1.3	E353L	Pathogenic	0.994
OPA1	O60313-1.3	E353M	Pathogenic	0.988
OPA1	O60313-1.3	E353N	Pathogenic	0.982
OPA1	O60313-1.3	E353P	Pathogenic	0.978
OPA1	O60313-1.3	E353Q	Pathogenic	0.822
OPA1	O60313-1.3	E353R	Pathogenic	0.973
OPA1	O60313-1.3	E353S	Pathogenic	0.967
OPA1	O60313-1.3	E353T	Pathogenic	0.986
OPA1	O60313-1.3	E353V	Pathogenic	0.989
OPA1	O60313-1.3	E353W	Pathogenic	0.988
OPA1	O60313-1.3	E353Y	Pathogenic	0.99
OPA1	O60313-1.3	E354A	Neutral	0.44
OPA1	O60313-1.3	E354C	Pathogenic	0.917
OPA1	O60313-1.3	E354D	Neutral	0.069
OPA1	O60313-1.3	E354F	Pathogenic	0.644
OPA1	O60313-1.3	E354G	Pathogenic	0.738
OPA1	O60313-1.3	E354H	Neutral	0.265
OPA1	O60313-1.3	E354I	Pathogenic	0.65
OPA1	O60313-1.3	E354K	Neutral	0.146
OPA1	O60313-1.3	E354L	Pathogenic	0.671
OPA1	O60313-1.3	E354M	Pathogenic	0.52
OPA1	O60313-1.3	E354N	Neutral	0.41
OPA1	O60313-1.3	E354P	Neutral	0.37
OPA1	O60313-1.3	E354Q	Neutral	0.057
OPA1	O60313-1.3	E354R	Neutral	0.318
OPA1	O60313-1.3	E354S	Neutral	0.275
OPA1	O60313-1.3	E354T	Neutral	0.476
OPA1	O60313-1.3	E354V	Pathogenic	0.533
OPA1	O60313-1.3	E354W	Pathogenic	0.516
OPA1	O60313-1.3	E354Y	Pathogenic	0.566
OPA1	O60313-1.3	D355A	Pathogenic	0.966
OPA1	O60313-1.3	D355C	Pathogenic	0.979
OPA1	O60313-1.3	D355E	Neutral	0.493
OPA1	O60313-1.3	D355F	Pathogenic	0.952
OPA1	O60313-1.3	D355G	Pathogenic	0.923
OPA1	O60313-1.3	D355H	Pathogenic	0.919
OPA1	O60313-1.3	D355I	Pathogenic	0.953
OPA1	O60313-1.3	D355K	Pathogenic	0.952
OPA1	O60313-1.3	D355L	Pathogenic	0.985
OPA1	O60313-1.3	D355M	Pathogenic	0.971
OPA1	O60313-1.3	D355N	Pathogenic	0.741
OPA1	O60313-1.3	D355P	Pathogenic	0.88
OPA1	O60313-1.3	D355Q	Pathogenic	0.846
OPA1	O60313-1.3	D355R	Pathogenic	0.982
OPA1	O60313-1.3	D355S	Pathogenic	0.825
OPA1	O60313-1.3	D355T	Pathogenic	0.917
OPA1	O60313-1.3	D355V	Pathogenic	0.974
OPA1	O60313-1.3	D355W	Pathogenic	0.971
OPA1	O60313-1.3	D355Y	Pathogenic	0.976
OPA1	O60313-1.3	L356A	Pathogenic	0.96
OPA1	O60313-1.3	L356C	Pathogenic	0.98
OPA1	O60313-1.3	L356D	Pathogenic	0.996
OPA1	O60313-1.3	L356E	Pathogenic	0.99
OPA1	O60313-1.3	L356F	Pathogenic	0.97
OPA1	O60313-1.3	L356G	Pathogenic	0.998
OPA1	O60313-1.3	L356H	Pathogenic	0.995
OPA1	O60313-1.3	L356I	Pathogenic	0.801
OPA1	O60313-1.3	L356K	Pathogenic	0.962
OPA1	O60313-1.3	L356M	Pathogenic	0.742
OPA1	O60313-1.3	L356N	Pathogenic	0.99
OPA1	O60313-1.3	L356P	Pathogenic	0.997
OPA1	O60313-1.3	L356Q	Pathogenic	0.981
OPA1	O60313-1.3	L356R	Pathogenic	0.96
OPA1	O60313-1.3	L356S	Pathogenic	0.981
OPA1	O60313-1.3	L356T	Pathogenic	0.962
OPA1	O60313-1.3	L356V	Pathogenic	0.884
OPA1	O60313-1.3	L356W	Pathogenic	0.994
OPA1	O60313-1.3	L356Y	Pathogenic	0.981
OPA1	O60313-1.3	A357C	Pathogenic	0.871
OPA1	O60313-1.3	A357D	Pathogenic	0.975
OPA1	O60313-1.3	A357E	Pathogenic	0.933
OPA1	O60313-1.3	A357F	Pathogenic	0.958
OPA1	O60313-1.3	A357G	Pathogenic	0.904
OPA1	O60313-1.3	A357H	Pathogenic	0.988
OPA1	O60313-1.3	A357I	Pathogenic	0.889
OPA1	O60313-1.3	A357K	Pathogenic	0.902
OPA1	O60313-1.3	A357L	Pathogenic	0.898
OPA1	O60313-1.3	A357M	Pathogenic	0.931
OPA1	O60313-1.3	A357N	Pathogenic	0.978
OPA1	O60313-1.3	A357P	Pathogenic	0.961
OPA1	O60313-1.3	A357Q	Pathogenic	0.953
OPA1	O60313-1.3	A357R	Pathogenic	0.897
OPA1	O60313-1.3	A357S	Pathogenic	0.768
OPA1	O60313-1.3	A357T	Pathogenic	0.921
OPA1	O60313-1.3	A357V	Pathogenic	0.835
OPA1	O60313-1.3	A357W	Pathogenic	0.975
OPA1	O60313-1.3	A357Y	Pathogenic	0.979
OPA1	O60313-1.3	A358C	Pathogenic	0.511
OPA1	O60313-1.3	A358D	Pathogenic	0.856
OPA1	O60313-1.3	A358E	Pathogenic	0.684
OPA1	O60313-1.3	A358F	Pathogenic	0.777
OPA1	O60313-1.3	A358G	Pathogenic	0.594
OPA1	O60313-1.3	A358H	Pathogenic	0.925
OPA1	O60313-1.3	A358I	Pathogenic	0.553
OPA1	O60313-1.3	A358K	Pathogenic	0.588
OPA1	O60313-1.3	A358L	Pathogenic	0.576
OPA1	O60313-1.3	A358M	Pathogenic	0.676
OPA1	O60313-1.3	A358N	Pathogenic	0.872
OPA1	O60313-1.3	A358P	Pathogenic	0.792
OPA1	O60313-1.3	A358Q	Pathogenic	0.757
OPA1	O60313-1.3	A358R	Pathogenic	0.573
OPA1	O60313-1.3	A358S	Neutral	0.338
OPA1	O60313-1.3	A358T	Pathogenic	0.643
OPA1	O60313-1.3	A358V	Neutral	0.44
OPA1	O60313-1.3	A358W	Pathogenic	0.857
OPA1	O60313-1.3	A358Y	Pathogenic	0.879
OPA1	O60313-1.3	L359A	Pathogenic	0.96
OPA1	O60313-1.3	L359C	Pathogenic	0.98
OPA1	O60313-1.3	L359D	Pathogenic	0.996
OPA1	O60313-1.3	L359E	Pathogenic	0.99
OPA1	O60313-1.3	L359F	Pathogenic	0.97
OPA1	O60313-1.3	L359G	Pathogenic	0.998
OPA1	O60313-1.3	L359H	Pathogenic	0.995
OPA1	O60313-1.3	L359I	Pathogenic	0.801
OPA1	O60313-1.3	L359K	Pathogenic	0.962
OPA1	O60313-1.3	L359M	Pathogenic	0.742
OPA1	O60313-1.3	L359N	Pathogenic	0.99
OPA1	O60313-1.3	L359P	Pathogenic	0.997
OPA1	O60313-1.3	L359Q	Pathogenic	0.981
OPA1	O60313-1.3	L359R	Pathogenic	0.96
OPA1	O60313-1.3	L359S	Pathogenic	0.981
OPA1	O60313-1.3	L359T	Pathogenic	0.962
OPA1	O60313-1.3	L359V	Pathogenic	0.884
OPA1	O60313-1.3	L359W	Pathogenic	0.994
OPA1	O60313-1.3	L359Y	Pathogenic	0.981
OPA1	O60313-1.3	R360A	Pathogenic	0.967
OPA1	O60313-1.3	R360C	Pathogenic	0.993
OPA1	O60313-1.3	R360D	Pathogenic	0.996
OPA1	O60313-1.3	R360E	Pathogenic	0.965
OPA1	O60313-1.3	R360F	Pathogenic	0.988
OPA1	O60313-1.3	R360G	Pathogenic	0.99
OPA1	O60313-1.3	R360H	Pathogenic	0.935
OPA1	O60313-1.3	R360I	Pathogenic	0.987
OPA1	O60313-1.3	R360K	Pathogenic	0.835
OPA1	O60313-1.3	R360L	Pathogenic	0.967
OPA1	O60313-1.3	R360M	Pathogenic	0.939
OPA1	O60313-1.3	R360N	Pathogenic	0.963
OPA1	O60313-1.3	R360P	Pathogenic	0.984
OPA1	O60313-1.3	R360Q	Pathogenic	0.87
OPA1	O60313-1.3	R360S	Pathogenic	0.976
OPA1	O60313-1.3	R360T	Pathogenic	0.971
OPA1	O60313-1.3	R360V	Pathogenic	0.992
OPA1	O60313-1.3	R360W	Pathogenic	0.981
OPA1	O60313-1.3	R360Y	Pathogenic	0.984
OPA1	O60313-1.3	H361A	Pathogenic	0.634
OPA1	O60313-1.3	H361C	Pathogenic	0.745
OPA1	O60313-1.3	H361D	Neutral	0.252
OPA1	O60313-1.3	H361E	Neutral	0.123
OPA1	O60313-1.3	H361F	Neutral	0.149
OPA1	O60313-1.3	H361G	Pathogenic	0.627
OPA1	O60313-1.3	H361I	Pathogenic	0.602
OPA1	O60313-1.3	H361K	Neutral	0.222
OPA1	O60313-1.3	H361L	Pathogenic	0.625
OPA1	O60313-1.3	H361M	Neutral	0.469
OPA1	O60313-1.3	H361N	Neutral	0.045
OPA1	O60313-1.3	H361P	Pathogenic	0.565
OPA1	O60313-1.3	H361Q	Neutral	0.173
OPA1	O60313-1.3	H361R	Neutral	0.085
OPA1	O60313-1.3	H361S	Neutral	0.381
OPA1	O60313-1.3	H361T	Pathogenic	0.667
OPA1	O60313-1.3	H361V	Pathogenic	0.716
OPA1	O60313-1.3	H361W	Neutral	0.231
OPA1	O60313-1.3	H361Y	Neutral	0.015
OPA1	O60313-1.3	E362A	Pathogenic	0.977
OPA1	O60313-1.3	E362C	Pathogenic	0.998
OPA1	O60313-1.3	E362D	Pathogenic	0.797
OPA1	O60313-1.3	E362F	Pathogenic	0.99
OPA1	O60313-1.3	E362G	Pathogenic	0.993
OPA1	O60313-1.3	E362H	Pathogenic	0.95
OPA1	O60313-1.3	E362I	Pathogenic	0.99
OPA1	O60313-1.3	E362K	Pathogenic	0.9
OPA1	O60313-1.3	E362L	Pathogenic	0.991
OPA1	O60313-1.3	E362M	Pathogenic	0.983
OPA1	O60313-1.3	E362N	Pathogenic	0.974
OPA1	O60313-1.3	E362P	Pathogenic	0.969
OPA1	O60313-1.3	E362Q	Pathogenic	0.761
OPA1	O60313-1.3	E362R	Pathogenic	0.961
OPA1	O60313-1.3	E362S	Pathogenic	0.953
OPA1	O60313-1.3	E362T	Pathogenic	0.98
OPA1	O60313-1.3	E362V	Pathogenic	0.984
OPA1	O60313-1.3	E362W	Pathogenic	0.983
OPA1	O60313-1.3	E362Y	Pathogenic	0.986
OPA1	O60313-1.3	I363A	Pathogenic	0.571
OPA1	O60313-1.3	I363C	Pathogenic	0.726
OPA1	O60313-1.3	I363D	Pathogenic	0.82
OPA1	O60313-1.3	I363E	Pathogenic	0.846
OPA1	O60313-1.3	I363F	Pathogenic	0.679
OPA1	O60313-1.3	I363G	Pathogenic	0.958
OPA1	O60313-1.3	I363H	Pathogenic	0.92
OPA1	O60313-1.3	I363K	Pathogenic	0.802
OPA1	O60313-1.3	I363L	Neutral	0.195
OPA1	O60313-1.3	I363M	Neutral	0.314
OPA1	O60313-1.3	I363N	Pathogenic	0.844
OPA1	O60313-1.3	I363P	Pathogenic	0.947
OPA1	O60313-1.3	I363Q	Pathogenic	0.892
OPA1	O60313-1.3	I363R	Pathogenic	0.792
OPA1	O60313-1.3	I363S	Pathogenic	0.742
OPA1	O60313-1.3	I363T	Pathogenic	0.583
OPA1	O60313-1.3	I363V	Neutral	0.048
OPA1	O60313-1.3	I363W	Pathogenic	0.969
OPA1	O60313-1.3	I363Y	Pathogenic	0.738
OPA1	O60313-1.3	E364A	Pathogenic	0.977
OPA1	O60313-1.3	E364C	Pathogenic	0.998
OPA1	O60313-1.3	E364D	Pathogenic	0.797
OPA1	O60313-1.3	E364F	Pathogenic	0.99
OPA1	O60313-1.3	E364G	Pathogenic	0.993
OPA1	O60313-1.3	E364H	Pathogenic	0.95
OPA1	O60313-1.3	E364I	Pathogenic	0.99
OPA1	O60313-1.3	E364K	Pathogenic	0.9
OPA1	O60313-1.3	E364L	Pathogenic	0.991
OPA1	O60313-1.3	E364M	Pathogenic	0.983
OPA1	O60313-1.3	E364N	Pathogenic	0.974
OPA1	O60313-1.3	E364P	Pathogenic	0.969
OPA1	O60313-1.3	E364Q	Pathogenic	0.761
OPA1	O60313-1.3	E364R	Pathogenic	0.961
OPA1	O60313-1.3	E364S	Pathogenic	0.953
OPA1	O60313-1.3	E364T	Pathogenic	0.98
OPA1	O60313-1.3	E364V	Pathogenic	0.984
OPA1	O60313-1.3	E364W	Pathogenic	0.983
OPA1	O60313-1.3	E364Y	Pathogenic	0.986
OPA1	O60313-1.3	L365A	Neutral	0.3
OPA1	O60313-1.3	L365C	Neutral	0.46
OPA1	O60313-1.3	L365D	Pathogenic	0.81
OPA1	O60313-1.3	L365E	Pathogenic	0.639
OPA1	O60313-1.3	L365F	Neutral	0.367
OPA1	O60313-1.3	L365G	Pathogenic	0.88
OPA1	O60313-1.3	L365H	Pathogenic	0.788
OPA1	O60313-1.3	L365I	Neutral	0.066
OPA1	O60313-1.3	L365K	Neutral	0.31
OPA1	O60313-1.3	L365M	Neutral	0.048
OPA1	O60313-1.3	L365N	Pathogenic	0.636
OPA1	O60313-1.3	L365P	Pathogenic	0.851
OPA1	O60313-1.3	L365Q	Neutral	0.477
OPA1	O60313-1.3	L365R	Neutral	0.297
OPA1	O60313-1.3	L365S	Neutral	0.481
OPA1	O60313-1.3	L365T	Neutral	0.311
OPA1	O60313-1.3	L365V	Neutral	0.119
OPA1	O60313-1.3	L365W	Pathogenic	0.742
OPA1	O60313-1.3	L365Y	Neutral	0.475
OPA1	O60313-1.3	R366A	Pathogenic	0.967
OPA1	O60313-1.3	R366C	Pathogenic	0.993
OPA1	O60313-1.3	R366D	Pathogenic	0.996
OPA1	O60313-1.3	R366E	Pathogenic	0.965
OPA1	O60313-1.3	R366F	Pathogenic	0.988
OPA1	O60313-1.3	R366G	Pathogenic	0.99
OPA1	O60313-1.3	R366H	Pathogenic	0.935
OPA1	O60313-1.3	R366I	Pathogenic	0.987
OPA1	O60313-1.3	R366K	Pathogenic	0.835
OPA1	O60313-1.3	R366L	Pathogenic	0.967
OPA1	O60313-1.3	R366M	Pathogenic	0.939
OPA1	O60313-1.3	R366N	Pathogenic	0.963
OPA1	O60313-1.3	R366P	Pathogenic	0.984
OPA1	O60313-1.3	R366Q	Pathogenic	0.87
OPA1	O60313-1.3	R366S	Pathogenic	0.976
OPA1	O60313-1.3	R366T	Pathogenic	0.971
OPA1	O60313-1.3	R366V	Pathogenic	0.992
OPA1	O60313-1.3	R366W	Pathogenic	0.981
OPA1	O60313-1.3	R366Y	Pathogenic	0.984
OPA1	O60313-1.3	M367A	Pathogenic	0.986
OPA1	O60313-1.3	M367C	Pathogenic	0.993
OPA1	O60313-1.3	M367D	Pathogenic	0.996
OPA1	O60313-1.3	M367E	Pathogenic	0.99
OPA1	O60313-1.3	M367F	Pathogenic	0.976
OPA1	O60313-1.3	M367G	Pathogenic	0.998
OPA1	O60313-1.3	M367H	Pathogenic	0.995
OPA1	O60313-1.3	M367I	Pathogenic	0.934
OPA1	O60313-1.3	M367K	Pathogenic	0.962
OPA1	O60313-1.3	M367L	Pathogenic	0.843
OPA1	O60313-1.3	M367N	Pathogenic	0.99
OPA1	O60313-1.3	M367P	Pathogenic	0.997
OPA1	O60313-1.3	M367Q	Pathogenic	0.946
OPA1	O60313-1.3	M367R	Pathogenic	0.959
OPA1	O60313-1.3	M367S	Pathogenic	0.981
OPA1	O60313-1.3	M367T	Pathogenic	0.987
OPA1	O60313-1.3	M367V	Pathogenic	0.956
OPA1	O60313-1.3	M367W	Pathogenic	0.986
OPA1	O60313-1.3	M367Y	Pathogenic	0.993
OPA1	O60313-1.3	R368A	Pathogenic	0.793
OPA1	O60313-1.3	R368C	Pathogenic	0.949
OPA1	O60313-1.3	R368D	Pathogenic	0.97
OPA1	O60313-1.3	R368E	Pathogenic	0.786
OPA1	O60313-1.3	R368F	Pathogenic	0.914
OPA1	O60313-1.3	R368G	Pathogenic	0.932
OPA1	O60313-1.3	R368H	Pathogenic	0.652
OPA1	O60313-1.3	R368I	Pathogenic	0.91
OPA1	O60313-1.3	R368K	Neutral	0.399
OPA1	O60313-1.3	R368L	Pathogenic	0.793
OPA1	O60313-1.3	R368M	Pathogenic	0.67
OPA1	O60313-1.3	R368N	Pathogenic	0.772
OPA1	O60313-1.3	R368P	Pathogenic	0.892
OPA1	O60313-1.3	R368Q	Neutral	0.468
OPA1	O60313-1.3	R368S	Pathogenic	0.843
OPA1	O60313-1.3	R368T	Pathogenic	0.815
OPA1	O60313-1.3	R368V	Pathogenic	0.942
OPA1	O60313-1.3	R368W	Pathogenic	0.874
OPA1	O60313-1.3	R368Y	Pathogenic	0.889
OPA1	O60313-1.3	K369A	Neutral	0.201
OPA1	O60313-1.3	K369C	Pathogenic	0.551
OPA1	O60313-1.3	K369D	Neutral	0.425
OPA1	O60313-1.3	K369E	Neutral	0.077
OPA1	O60313-1.3	K369F	Neutral	0.413
OPA1	O60313-1.3	K369G	Neutral	0.474
OPA1	O60313-1.3	K369H	Neutral	0.263
OPA1	O60313-1.3	K369I	Neutral	0.4
OPA1	O60313-1.3	K369L	Neutral	0.201
OPA1	O60313-1.3	K369M	Neutral	0.118
OPA1	O60313-1.3	K369N	Neutral	0.182
OPA1	O60313-1.3	K369P	Neutral	0.158
OPA1	O60313-1.3	K369Q	Neutral	0.055
OPA1	O60313-1.3	K369R	Neutral	0.039
OPA1	O60313-1.3	K369S	Neutral	0.108
OPA1	O60313-1.3	K369T	Neutral	0.225
OPA1	O60313-1.3	K369V	Neutral	0.268
OPA1	O60313-1.3	K369W	Neutral	0.293
OPA1	O60313-1.3	K369Y	Neutral	0.336
OPA1	O60313-1.3	N370A	Pathogenic	0.776
OPA1	O60313-1.3	N370C	Pathogenic	0.854
OPA1	O60313-1.3	N370D	Neutral	0.235
OPA1	O60313-1.3	N370E	Neutral	0.494
OPA1	O60313-1.3	N370F	Pathogenic	0.714
OPA1	O60313-1.3	N370G	Neutral	0.338
OPA1	O60313-1.3	N370H	Neutral	0.147
OPA1	O60313-1.3	N370I	Pathogenic	0.72
OPA1	O60313-1.3	N370K	Neutral	0.391
OPA1	O60313-1.3	N370L	Pathogenic	0.739
OPA1	O60313-1.3	N370M	Pathogenic	0.6
OPA1	O60313-1.3	N370P	Pathogenic	0.722
OPA1	O60313-1.3	N370Q	Neutral	0.411
OPA1	O60313-1.3	N370R	Neutral	0.376
OPA1	O60313-1.3	N370S	Neutral	0.167
OPA1	O60313-1.3	N370T	Neutral	0.323
OPA1	O60313-1.3	N370V	Pathogenic	0.825
OPA1	O60313-1.3	N370W	Pathogenic	0.811
OPA1	O60313-1.3	N370Y	Pathogenic	0.643
OPA1	O60313-1.3	V371A	Pathogenic	0.945
OPA1	O60313-1.3	V371C	Pathogenic	0.99
OPA1	O60313-1.3	V371D	Pathogenic	0.994
OPA1	O60313-1.3	V371E	Pathogenic	0.986
OPA1	O60313-1.3	V371F	Pathogenic	0.986
OPA1	O60313-1.3	V371G	Pathogenic	0.997
OPA1	O60313-1.3	V371H	Pathogenic	0.997
OPA1	O60313-1.3	V371I	Pathogenic	0.503
OPA1	O60313-1.3	V371K	Pathogenic	0.978
OPA1	O60313-1.3	V371L	Pathogenic	0.903
OPA1	O60313-1.3	V371M	Pathogenic	0.935
OPA1	O60313-1.3	V371N	Pathogenic	0.995
OPA1	O60313-1.3	V371P	Pathogenic	0.996
OPA1	O60313-1.3	V371Q	Pathogenic	0.99
OPA1	O60313-1.3	V371R	Pathogenic	0.992
OPA1	O60313-1.3	V371S	Pathogenic	0.991
OPA1	O60313-1.3	V371T	Pathogenic	0.947
OPA1	O60313-1.3	V371W	Pathogenic	0.997
OPA1	O60313-1.3	V371Y	Pathogenic	0.989
OPA1	O60313-1.3	K372A	Pathogenic	0.792
OPA1	O60313-1.3	K372C	Pathogenic	0.949
OPA1	O60313-1.3	K372D	Pathogenic	0.918
OPA1	O60313-1.3	K372E	Pathogenic	0.557
OPA1	O60313-1.3	K372F	Pathogenic	0.914
OPA1	O60313-1.3	K372G	Pathogenic	0.932
OPA1	O60313-1.3	K372H	Pathogenic	0.844
OPA1	O60313-1.3	K372I	Pathogenic	0.91
OPA1	O60313-1.3	K372L	Pathogenic	0.792
OPA1	O60313-1.3	K372M	Pathogenic	0.669
OPA1	O60313-1.3	K372N	Pathogenic	0.771
OPA1	O60313-1.3	K372P	Pathogenic	0.74
OPA1	O60313-1.3	K372Q	Neutral	0.467
OPA1	O60313-1.3	K372R	Neutral	0.383
OPA1	O60313-1.3	K372S	Pathogenic	0.648
OPA1	O60313-1.3	K372T	Pathogenic	0.815
OPA1	O60313-1.3	K372V	Pathogenic	0.847
OPA1	O60313-1.3	K372W	Pathogenic	0.863
OPA1	O60313-1.3	K372Y	Pathogenic	0.884
OPA1	O60313-1.3	E373A	Neutral	0.454
OPA1	O60313-1.3	E373C	Pathogenic	0.921
OPA1	O60313-1.3	E373D	Neutral	0.073
OPA1	O60313-1.3	E373F	Pathogenic	0.657
OPA1	O60313-1.3	E373G	Pathogenic	0.748
OPA1	O60313-1.3	E373H	Neutral	0.276
OPA1	O60313-1.3	E373I	Pathogenic	0.663
OPA1	O60313-1.3	E373K	Neutral	0.153
OPA1	O60313-1.3	E373L	Pathogenic	0.683
OPA1	O60313-1.3	E373M	Pathogenic	0.534
OPA1	O60313-1.3	E373N	Neutral	0.423
OPA1	O60313-1.3	E373P	Neutral	0.383
OPA1	O60313-1.3	E373Q	Neutral	0.06
OPA1	O60313-1.3	E373R	Neutral	0.33
OPA1	O60313-1.3	E373S	Neutral	0.287
OPA1	O60313-1.3	E373T	Neutral	0.49
OPA1	O60313-1.3	E373V	Pathogenic	0.547
OPA1	O60313-1.3	E373W	Pathogenic	0.53
OPA1	O60313-1.3	E373Y	Pathogenic	0.579
OPA1	O60313-1.3	G374A	Pathogenic	0.975
OPA1	O60313-1.3	G374C	Pathogenic	0.998
OPA1	O60313-1.3	G374D	Pathogenic	0.985
OPA1	O60313-1.3	G374E	Pathogenic	0.995
OPA1	O60313-1.3	G374F	Pathogenic	0.995
OPA1	O60313-1.3	G374H	Pathogenic	0.997
OPA1	O60313-1.3	G374I	Pathogenic	0.998
OPA1	O60313-1.3	G374K	Pathogenic	0.993
OPA1	O60313-1.3	G374L	Pathogenic	0.998
OPA1	O60313-1.3	G374M	Pathogenic	0.997
OPA1	O60313-1.3	G374N	Pathogenic	0.964
OPA1	O60313-1.3	G374P	Pathogenic	0.995
OPA1	O60313-1.3	G374Q	Pathogenic	0.997
OPA1	O60313-1.3	G374R	Pathogenic	0.992
OPA1	O60313-1.3	G374S	Pathogenic	0.98
OPA1	O60313-1.3	G374T	Pathogenic	0.997
OPA1	O60313-1.3	G374V	Pathogenic	0.997
OPA1	O60313-1.3	G374W	Pathogenic	0.975
OPA1	O60313-1.3	G374Y	Pathogenic	0.997
OPA1	O60313-1.3	C375A	Neutral	0.098
OPA1	O60313-1.3	C375D	Pathogenic	0.509
OPA1	O60313-1.3	C375E	Pathogenic	0.76
OPA1	O60313-1.3	C375F	Neutral	0.419
OPA1	O60313-1.3	C375G	Pathogenic	0.649
OPA1	O60313-1.3	C375H	Pathogenic	0.681
OPA1	O60313-1.3	C375I	Neutral	0.203
OPA1	O60313-1.3	C375K	Neutral	0.418
OPA1	O60313-1.3	C375L	Neutral	0.219
OPA1	O60313-1.3	C375M	Neutral	0.301
OPA1	O60313-1.3	C375N	Pathogenic	0.543
OPA1	O60313-1.3	C375P	Pathogenic	0.802
OPA1	O60313-1.3	C375Q	Pathogenic	0.611
OPA1	O60313-1.3	C375R	Neutral	0.403
OPA1	O60313-1.3	C375S	Neutral	0.19
OPA1	O60313-1.3	C375T	Neutral	0.238
OPA1	O60313-1.3	C375V	Neutral	0.319
OPA1	O60313-1.3	C375W	Neutral	0.298
OPA1	O60313-1.3	C375Y	Pathogenic	0.591
OPA1	O60313-1.3	T376A	Pathogenic	0.977
OPA1	O60313-1.3	T376C	Pathogenic	0.986
OPA1	O60313-1.3	T376D	Pathogenic	0.982
OPA1	O60313-1.3	T376E	Pathogenic	0.983
OPA1	O60313-1.3	T376F	Pathogenic	0.989
OPA1	O60313-1.3	T376G	Pathogenic	0.996
OPA1	O60313-1.3	T376H	Pathogenic	0.997
OPA1	O60313-1.3	T376I	Pathogenic	0.969
OPA1	O60313-1.3	T376K	Pathogenic	0.975
OPA1	O60313-1.3	T376L	Pathogenic	0.971
OPA1	O60313-1.3	T376M	Pathogenic	0.981
OPA1	O60313-1.3	T376N	Pathogenic	0.957
OPA1	O60313-1.3	T376P	Pathogenic	0.989
OPA1	O60313-1.3	T376Q	Pathogenic	0.988
OPA1	O60313-1.3	T376R	Pathogenic	0.973
OPA1	O60313-1.3	T376S	Pathogenic	0.923
OPA1	O60313-1.3	T376V	Pathogenic	0.951
OPA1	O60313-1.3	T376W	Pathogenic	0.981
OPA1	O60313-1.3	T376Y	Pathogenic	0.995
OPA1	O60313-1.3	V377A	Pathogenic	0.89
OPA1	O60313-1.3	V377C	Pathogenic	0.979
OPA1	O60313-1.3	V377D	Pathogenic	0.988
OPA1	O60313-1.3	V377E	Pathogenic	0.97
OPA1	O60313-1.3	V377F	Pathogenic	0.971
OPA1	O60313-1.3	V377G	Pathogenic	0.993
OPA1	O60313-1.3	V377H	Pathogenic	0.995
OPA1	O60313-1.3	V377I	Neutral	0.325
OPA1	O60313-1.3	V377K	Pathogenic	0.955
OPA1	O60313-1.3	V377L	Pathogenic	0.816
OPA1	O60313-1.3	V377M	Pathogenic	0.872
OPA1	O60313-1.3	V377N	Pathogenic	0.99
OPA1	O60313-1.3	V377P	Pathogenic	0.991
OPA1	O60313-1.3	V377Q	Pathogenic	0.979
OPA1	O60313-1.3	V377R	Pathogenic	0.983
OPA1	O60313-1.3	V377S	Pathogenic	0.981
OPA1	O60313-1.3	V377T	Pathogenic	0.895
OPA1	O60313-1.3	V377W	Pathogenic	0.994
OPA1	O60313-1.3	V377Y	Pathogenic	0.977
OPA1	O60313-1.3	S378A	Pathogenic	0.917
OPA1	O60313-1.3	S378C	Pathogenic	0.98
OPA1	O60313-1.3	S378D	Pathogenic	0.955
OPA1	O60313-1.3	S378E	Pathogenic	0.958
OPA1	O60313-1.3	S378F	Pathogenic	0.983
OPA1	O60313-1.3	S378G	Pathogenic	0.975
OPA1	O60313-1.3	S378H	Pathogenic	0.99
OPA1	O60313-1.3	S378I	Pathogenic	0.983
OPA1	O60313-1.3	S378K	Pathogenic	0.937
OPA1	O60313-1.3	S378L	Pathogenic	0.985
OPA1	O60313-1.3	S378M	Pathogenic	0.971
OPA1	O60313-1.3	S378N	Pathogenic	0.894
OPA1	O60313-1.3	S378P	Pathogenic	0.984
OPA1	O60313-1.3	S378Q	Pathogenic	0.97
OPA1	O60313-1.3	S378R	Pathogenic	0.976
OPA1	O60313-1.3	S378T	Pathogenic	0.917
OPA1	O60313-1.3	S378V	Pathogenic	0.991
OPA1	O60313-1.3	S378W	Pathogenic	0.99
OPA1	O60313-1.3	S378Y	Pathogenic	0.992
OPA1	O60313-1.3	P379A	Neutral	0.06
OPA1	O60313-1.3	P379C	Neutral	0.397
OPA1	O60313-1.3	P379D	Neutral	0.025
OPA1	O60313-1.3	P379E	Neutral	0.027
OPA1	O60313-1.3	P379F	Neutral	0.439
OPA1	O60313-1.3	P379G	Neutral	0.115
OPA1	O60313-1.3	P379H	Neutral	0.134
OPA1	O60313-1.3	P379I	Neutral	0.217
OPA1	O60313-1.3	P379K	Neutral	0.018
OPA1	O60313-1.3	P379L	Neutral	0.234
OPA1	O60313-1.3	P379M	Neutral	0.139
OPA1	O60313-1.3	P379N	Neutral	0.079
OPA1	O60313-1.3	P379Q	Neutral	0.038
OPA1	O60313-1.3	P379R	Neutral	0.047
OPA1	O60313-1.3	P379S	Neutral	0.045
OPA1	O60313-1.3	P379T	Neutral	0.062
OPA1	O60313-1.3	P379V	Neutral	0.15
OPA1	O60313-1.3	P379W	Neutral	0.316
OPA1	O60313-1.3	P379Y	Neutral	0.361
OPA1	O60313-1.3	E380A	Pathogenic	0.798
OPA1	O60313-1.3	E380C	Pathogenic	0.982
OPA1	O60313-1.3	E380D	Neutral	0.272
OPA1	O60313-1.3	E380F	Pathogenic	0.901
OPA1	O60313-1.3	E380G	Pathogenic	0.934
OPA1	O60313-1.3	E380H	Pathogenic	0.644
OPA1	O60313-1.3	E380I	Pathogenic	0.903
OPA1	O60313-1.3	E380K	Neutral	0.462
OPA1	O60313-1.3	E380L	Pathogenic	0.911
OPA1	O60313-1.3	E380M	Pathogenic	0.845
OPA1	O60313-1.3	E380N	Pathogenic	0.777
OPA1	O60313-1.3	E380P	Pathogenic	0.747
OPA1	O60313-1.3	E380Q	Neutral	0.232
OPA1	O60313-1.3	E380R	Pathogenic	0.701
OPA1	O60313-1.3	E380S	Pathogenic	0.656
OPA1	O60313-1.3	E380T	Pathogenic	0.82
OPA1	O60313-1.3	E380V	Pathogenic	0.852
OPA1	O60313-1.3	E380W	Pathogenic	0.843
OPA1	O60313-1.3	E380Y	Pathogenic	0.867
OPA1	O60313-1.3	T381A	Pathogenic	0.738
OPA1	O60313-1.3	T381C	Pathogenic	0.825
OPA1	O60313-1.3	T381D	Pathogenic	0.785
OPA1	O60313-1.3	T381E	Pathogenic	0.796
OPA1	O60313-1.3	T381F	Pathogenic	0.852
OPA1	O60313-1.3	T381G	Pathogenic	0.948
OPA1	O60313-1.3	T381H	Pathogenic	0.957
OPA1	O60313-1.3	T381I	Pathogenic	0.67
OPA1	O60313-1.3	T381K	Pathogenic	0.72
OPA1	O60313-1.3	T381L	Pathogenic	0.691
OPA1	O60313-1.3	T381M	Pathogenic	0.774
OPA1	O60313-1.3	T381N	Pathogenic	0.594
OPA1	O60313-1.3	T381P	Pathogenic	0.859
OPA1	O60313-1.3	T381Q	Pathogenic	0.849
OPA1	O60313-1.3	T381R	Pathogenic	0.707
OPA1	O60313-1.3	T381S	Neutral	0.443
OPA1	O60313-1.3	T381V	Pathogenic	0.563
OPA1	O60313-1.3	T381W	Pathogenic	0.772
OPA1	O60313-1.3	T381Y	Pathogenic	0.923
OPA1	O60313-1.3	I382A	Pathogenic	0.967
OPA1	O60313-1.3	I382C	Pathogenic	0.983
OPA1	O60313-1.3	I382D	Pathogenic	0.99
OPA1	O60313-1.3	I382E	Pathogenic	0.992
OPA1	O60313-1.3	I382F	Pathogenic	0.979
OPA1	O60313-1.3	I382G	Pathogenic	0.998
OPA1	O60313-1.3	I382H	Pathogenic	0.996
OPA1	O60313-1.3	I382K	Pathogenic	0.989
OPA1	O60313-1.3	I382L	Pathogenic	0.842
OPA1	O60313-1.3	I382M	Pathogenic	0.91
OPA1	O60313-1.3	I382N	Pathogenic	0.992
OPA1	O60313-1.3	I382P	Pathogenic	0.997
OPA1	O60313-1.3	I382Q	Pathogenic	0.995
OPA1	O60313-1.3	I382R	Pathogenic	0.988
OPA1	O60313-1.3	I382S	Pathogenic	0.985
OPA1	O60313-1.3	I382T	Pathogenic	0.969
OPA1	O60313-1.3	I382V	Pathogenic	0.524
OPA1	O60313-1.3	I382W	Pathogenic	0.999
OPA1	O60313-1.3	I382Y	Pathogenic	0.984
OPA1	O60313-1.3	S383A	Pathogenic	0.898
OPA1	O60313-1.3	S383C	Pathogenic	0.975
OPA1	O60313-1.3	S383D	Pathogenic	0.945
OPA1	O60313-1.3	S383E	Pathogenic	0.947
OPA1	O60313-1.3	S383F	Pathogenic	0.978
OPA1	O60313-1.3	S383G	Pathogenic	0.969
OPA1	O60313-1.3	S383H	Pathogenic	0.987
OPA1	O60313-1.3	S383I	Pathogenic	0.979
OPA1	O60313-1.3	S383K	Pathogenic	0.922
OPA1	O60313-1.3	S383L	Pathogenic	0.981
OPA1	O60313-1.3	S383M	Pathogenic	0.964
OPA1	O60313-1.3	S383N	Pathogenic	0.871
OPA1	O60313-1.3	S383P	Pathogenic	0.98
OPA1	O60313-1.3	S383Q	Pathogenic	0.963
OPA1	O60313-1.3	S383R	Pathogenic	0.97
OPA1	O60313-1.3	S383T	Pathogenic	0.897
OPA1	O60313-1.3	S383V	Pathogenic	0.988
OPA1	O60313-1.3	S383W	Pathogenic	0.987
OPA1	O60313-1.3	S383Y	Pathogenic	0.989
OPA1	O60313-1.3	L384A	Pathogenic	0.787
OPA1	O60313-1.3	L384C	Pathogenic	0.88
OPA1	O60313-1.3	L384D	Pathogenic	0.974
OPA1	O60313-1.3	L384E	Pathogenic	0.939
OPA1	O60313-1.3	L384F	Pathogenic	0.833
OPA1	O60313-1.3	L384G	Pathogenic	0.984
OPA1	O60313-1.3	L384H	Pathogenic	0.97
OPA1	O60313-1.3	L384I	Neutral	0.379
OPA1	O60313-1.3	L384K	Pathogenic	0.795
OPA1	O60313-1.3	L384M	Neutral	0.304
OPA1	O60313-1.3	L384N	Pathogenic	0.938
OPA1	O60313-1.3	L384P	Pathogenic	0.98
OPA1	O60313-1.3	L384Q	Pathogenic	0.887
OPA1	O60313-1.3	L384R	Pathogenic	0.785
OPA1	O60313-1.3	L384S	Pathogenic	0.889
OPA1	O60313-1.3	L384T	Pathogenic	0.795
OPA1	O60313-1.3	L384V	Pathogenic	0.538
OPA1	O60313-1.3	L384W	Pathogenic	0.961
OPA1	O60313-1.3	L384Y	Pathogenic	0.886
OPA1	O60313-1.3	N385A	Neutral	0.371
OPA1	O60313-1.3	N385C	Neutral	0.498
OPA1	O60313-1.3	N385D	Neutral	0.05
OPA1	O60313-1.3	N385E	Neutral	0.142
OPA1	O60313-1.3	N385F	Neutral	0.298
OPA1	O60313-1.3	N385G	Neutral	0.08
OPA1	O60313-1.3	N385H	Neutral	0.028
OPA1	O60313-1.3	N385I	Neutral	0.304
OPA1	O60313-1.3	N385K	Neutral	0.098
OPA1	O60313-1.3	N385L	Neutral	0.324
OPA1	O60313-1.3	N385M	Neutral	0.203
OPA1	O60313-1.3	N385P	Neutral	0.306
OPA1	O60313-1.3	N385Q	Neutral	0.106
OPA1	O60313-1.3	N385R	Neutral	0.093
OPA1	O60313-1.3	N385S	Neutral	0.033
OPA1	O60313-1.3	N385T	Neutral	0.075
OPA1	O60313-1.3	N385V	Neutral	0.445
OPA1	O60313-1.3	N385W	Neutral	0.421
OPA1	O60313-1.3	N385Y	Neutral	0.234
OPA1	O60313-1.3	V386A	Pathogenic	0.945
OPA1	O60313-1.3	V386C	Pathogenic	0.99
OPA1	O60313-1.3	V386D	Pathogenic	0.994
OPA1	O60313-1.3	V386E	Pathogenic	0.986
OPA1	O60313-1.3	V386F	Pathogenic	0.986
OPA1	O60313-1.3	V386G	Pathogenic	0.997
OPA1	O60313-1.3	V386H	Pathogenic	0.997
OPA1	O60313-1.3	V386I	Pathogenic	0.503
OPA1	O60313-1.3	V386K	Pathogenic	0.978
OPA1	O60313-1.3	V386L	Pathogenic	0.903
OPA1	O60313-1.3	V386M	Pathogenic	0.935
OPA1	O60313-1.3	V386N	Pathogenic	0.995
OPA1	O60313-1.3	V386P	Pathogenic	0.996
OPA1	O60313-1.3	V386Q	Pathogenic	0.99
OPA1	O60313-1.3	V386R	Pathogenic	0.992
OPA1	O60313-1.3	V386S	Pathogenic	0.991
OPA1	O60313-1.3	V386T	Pathogenic	0.947
OPA1	O60313-1.3	V386W	Pathogenic	0.997
OPA1	O60313-1.3	V386Y	Pathogenic	0.989
OPA1	O60313-1.3	K387A	Pathogenic	0.963
OPA1	O60313-1.3	K387C	Pathogenic	0.992
OPA1	O60313-1.3	K387D	Pathogenic	0.987
OPA1	O60313-1.3	K387E	Pathogenic	0.897
OPA1	O60313-1.3	K387F	Pathogenic	0.987
OPA1	O60313-1.3	K387G	Pathogenic	0.99
OPA1	O60313-1.3	K387H	Pathogenic	0.974
OPA1	O60313-1.3	K387I	Pathogenic	0.986
OPA1	O60313-1.3	K387L	Pathogenic	0.964
OPA1	O60313-1.3	K387M	Pathogenic	0.933
OPA1	O60313-1.3	K387N	Pathogenic	0.959
OPA1	O60313-1.3	K387P	Pathogenic	0.952
OPA1	O60313-1.3	K387Q	Pathogenic	0.859
OPA1	O60313-1.3	K387R	Pathogenic	0.811
OPA1	O60313-1.3	K387S	Pathogenic	0.927
OPA1	O60313-1.3	K387T	Pathogenic	0.968
OPA1	O60313-1.3	K387V	Pathogenic	0.975
OPA1	O60313-1.3	K387W	Pathogenic	0.978
OPA1	O60313-1.3	K387Y	Pathogenic	0.982
OPA1	O60313-1.3	G388A	Pathogenic	0.975
OPA1	O60313-1.3	G388C	Pathogenic	0.998
OPA1	O60313-1.3	G388D	Pathogenic	0.985
OPA1	O60313-1.3	G388E	Pathogenic	0.995
OPA1	O60313-1.3	G388F	Pathogenic	0.995
OPA1	O60313-1.3	G388H	Pathogenic	0.997
OPA1	O60313-1.3	G388I	Pathogenic	0.998
OPA1	O60313-1.3	G388K	Pathogenic	0.993
OPA1	O60313-1.3	G388L	Pathogenic	0.998
OPA1	O60313-1.3	G388M	Pathogenic	0.997
OPA1	O60313-1.3	G388N	Pathogenic	0.964
OPA1	O60313-1.3	G388P	Pathogenic	0.995
OPA1	O60313-1.3	G388Q	Pathogenic	0.997
OPA1	O60313-1.3	G388R	Pathogenic	0.992
OPA1	O60313-1.3	G388S	Pathogenic	0.98
OPA1	O60313-1.3	G388T	Pathogenic	0.997
OPA1	O60313-1.3	G388V	Pathogenic	0.997
OPA1	O60313-1.3	G388W	Pathogenic	0.975
OPA1	O60313-1.3	G388Y	Pathogenic	0.997
OPA1	O60313-1.3	P389A	Pathogenic	0.991
OPA1	O60313-1.3	P389C	Pathogenic	0.999
OPA1	O60313-1.3	P389D	Pathogenic	0.978
OPA1	O60313-1.3	P389E	Pathogenic	0.979
OPA1	O60313-1.3	P389F	Pathogenic	0.999
OPA1	O60313-1.3	P389G	Pathogenic	0.996
OPA1	O60313-1.3	P389H	Pathogenic	0.996
OPA1	O60313-1.3	P389I	Pathogenic	0.998
OPA1	O60313-1.3	P389K	Pathogenic	0.968
OPA1	O60313-1.3	P389L	Pathogenic	0.998
OPA1	O60313-1.3	P389M	Pathogenic	0.996
OPA1	O60313-1.3	P389N	Pathogenic	0.993
OPA1	O60313-1.3	P389Q	Pathogenic	0.985
OPA1	O60313-1.3	P389R	Pathogenic	0.988
OPA1	O60313-1.3	P389S	Pathogenic	0.988
OPA1	O60313-1.3	P389T	Pathogenic	0.991
OPA1	O60313-1.3	P389V	Pathogenic	0.997
OPA1	O60313-1.3	P389W	Pathogenic	0.999
OPA1	O60313-1.3	P389Y	Pathogenic	0.999
OPA1	O60313-1.3	G390A	Pathogenic	0.975
OPA1	O60313-1.3	G390C	Pathogenic	0.998
OPA1	O60313-1.3	G390D	Pathogenic	0.985
OPA1	O60313-1.3	G390E	Pathogenic	0.995
OPA1	O60313-1.3	G390F	Pathogenic	0.995
OPA1	O60313-1.3	G390H	Pathogenic	0.997
OPA1	O60313-1.3	G390I	Pathogenic	0.998
OPA1	O60313-1.3	G390K	Pathogenic	0.993
OPA1	O60313-1.3	G390L	Pathogenic	0.998
OPA1	O60313-1.3	G390M	Pathogenic	0.997
OPA1	O60313-1.3	G390N	Pathogenic	0.964
OPA1	O60313-1.3	G390P	Pathogenic	0.995
OPA1	O60313-1.3	G390Q	Pathogenic	0.997
OPA1	O60313-1.3	G390R	Pathogenic	0.992
OPA1	O60313-1.3	G390S	Pathogenic	0.98
OPA1	O60313-1.3	G390T	Pathogenic	0.997
OPA1	O60313-1.3	G390V	Pathogenic	0.997
OPA1	O60313-1.3	G390W	Pathogenic	0.975
OPA1	O60313-1.3	G390Y	Pathogenic	0.997
OPA1	O60313-1.3	L391A	Pathogenic	0.71
OPA1	O60313-1.3	L391C	Pathogenic	0.83
OPA1	O60313-1.3	L391D	Pathogenic	0.961
OPA1	O60313-1.3	L391E	Pathogenic	0.91
OPA1	O60313-1.3	L391F	Pathogenic	0.768
OPA1	O60313-1.3	L391G	Pathogenic	0.977
OPA1	O60313-1.3	L391H	Pathogenic	0.955
OPA1	O60313-1.3	L391I	Neutral	0.288
OPA1	O60313-1.3	L391K	Pathogenic	0.72
OPA1	O60313-1.3	L391M	Neutral	0.225
OPA1	O60313-1.3	L391N	Pathogenic	0.909
OPA1	O60313-1.3	L391P	Pathogenic	0.97
OPA1	O60313-1.3	L391Q	Pathogenic	0.839
OPA1	O60313-1.3	L391R	Pathogenic	0.707
OPA1	O60313-1.3	L391S	Pathogenic	0.841
OPA1	O60313-1.3	L391T	Pathogenic	0.72
OPA1	O60313-1.3	L391V	Neutral	0.436
OPA1	O60313-1.3	L391W	Pathogenic	0.943
OPA1	O60313-1.3	L391Y	Pathogenic	0.838
OPA1	O60313-1.3	Q392A	Pathogenic	0.965
OPA1	O60313-1.3	Q392C	Pathogenic	0.993
OPA1	O60313-1.3	Q392D	Pathogenic	0.91
OPA1	O60313-1.3	Q392E	Pathogenic	0.592
OPA1	O60313-1.3	Q392F	Pathogenic	0.985
OPA1	O60313-1.3	Q392G	Pathogenic	0.99
OPA1	O60313-1.3	Q392H	Pathogenic	0.928
OPA1	O60313-1.3	Q392I	Pathogenic	0.985
OPA1	O60313-1.3	Q392K	Pathogenic	0.741
OPA1	O60313-1.3	Q392L	Pathogenic	0.962
OPA1	O60313-1.3	Q392M	Pathogenic	0.823
OPA1	O60313-1.3	Q392N	Pathogenic	0.923
OPA1	O60313-1.3	Q392P	Pathogenic	0.953
OPA1	O60313-1.3	Q392R	Pathogenic	0.729
OPA1	O60313-1.3	Q392S	Pathogenic	0.93
OPA1	O60313-1.3	Q392T	Pathogenic	0.969
OPA1	O60313-1.3	Q392V	Pathogenic	0.975
OPA1	O60313-1.3	Q392W	Pathogenic	0.93
OPA1	O60313-1.3	Q392Y	Pathogenic	0.942
OPA1	O60313-1.3	R393A	Pathogenic	0.985
OPA1	O60313-1.3	R393C	Pathogenic	0.997
OPA1	O60313-1.3	R393D	Pathogenic	0.998
OPA1	O60313-1.3	R393E	Pathogenic	0.985
OPA1	O60313-1.3	R393F	Pathogenic	0.995
OPA1	O60313-1.3	R393G	Pathogenic	0.996
OPA1	O60313-1.3	R393H	Pathogenic	0.97
OPA1	O60313-1.3	R393I	Pathogenic	0.994
OPA1	O60313-1.3	R393K	Pathogenic	0.921
OPA1	O60313-1.3	R393L	Pathogenic	0.985
OPA1	O60313-1.3	R393M	Pathogenic	0.973
OPA1	O60313-1.3	R393N	Pathogenic	0.983
OPA1	O60313-1.3	R393P	Pathogenic	0.993
OPA1	O60313-1.3	R393Q	Pathogenic	0.939
OPA1	O60313-1.3	R393S	Pathogenic	0.989
OPA1	O60313-1.3	R393T	Pathogenic	0.987
OPA1	O60313-1.3	R393V	Pathogenic	0.996
OPA1	O60313-1.3	R393W	Pathogenic	0.992
OPA1	O60313-1.3	R393Y	Pathogenic	0.993
OPA1	O60313-1.3	M394A	Pathogenic	0.986
OPA1	O60313-1.3	M394C	Pathogenic	0.993
OPA1	O60313-1.3	M394D	Pathogenic	0.996
OPA1	O60313-1.3	M394E	Pathogenic	0.99
OPA1	O60313-1.3	M394F	Pathogenic	0.976
OPA1	O60313-1.3	M394G	Pathogenic	0.998
OPA1	O60313-1.3	M394H	Pathogenic	0.995
OPA1	O60313-1.3	M394I	Pathogenic	0.934
OPA1	O60313-1.3	M394K	Pathogenic	0.962
OPA1	O60313-1.3	M394L	Pathogenic	0.843
OPA1	O60313-1.3	M394N	Pathogenic	0.99
OPA1	O60313-1.3	M394P	Pathogenic	0.997
OPA1	O60313-1.3	M394Q	Pathogenic	0.946
OPA1	O60313-1.3	M394R	Pathogenic	0.959
OPA1	O60313-1.3	M394S	Pathogenic	0.981
OPA1	O60313-1.3	M394T	Pathogenic	0.987
OPA1	O60313-1.3	M394V	Pathogenic	0.956
OPA1	O60313-1.3	M394W	Pathogenic	0.986
OPA1	O60313-1.3	M394Y	Pathogenic	0.993
OPA1	O60313-1.3	V395A	Pathogenic	0.945
OPA1	O60313-1.3	V395C	Pathogenic	0.99
OPA1	O60313-1.3	V395D	Pathogenic	0.994
OPA1	O60313-1.3	V395E	Pathogenic	0.986
OPA1	O60313-1.3	V395F	Pathogenic	0.986
OPA1	O60313-1.3	V395G	Pathogenic	0.997
OPA1	O60313-1.3	V395H	Pathogenic	0.997
OPA1	O60313-1.3	V395I	Pathogenic	0.503
OPA1	O60313-1.3	V395K	Pathogenic	0.978
OPA1	O60313-1.3	V395L	Pathogenic	0.903
OPA1	O60313-1.3	V395M	Pathogenic	0.935
OPA1	O60313-1.3	V395N	Pathogenic	0.995
OPA1	O60313-1.3	V395P	Pathogenic	0.996
OPA1	O60313-1.3	V395Q	Pathogenic	0.99
OPA1	O60313-1.3	V395R	Pathogenic	0.992
OPA1	O60313-1.3	V395S	Pathogenic	0.991
OPA1	O60313-1.3	V395T	Pathogenic	0.947
OPA1	O60313-1.3	V395W	Pathogenic	0.997
OPA1	O60313-1.3	V395Y	Pathogenic	0.989
OPA1	O60313-1.3	L396A	Pathogenic	0.982
OPA1	O60313-1.3	L396C	Pathogenic	0.991
OPA1	O60313-1.3	L396D	Pathogenic	0.998
OPA1	O60313-1.3	L396E	Pathogenic	0.996
OPA1	O60313-1.3	L396F	Pathogenic	0.987
OPA1	O60313-1.3	L396G	Pathogenic	0.999
OPA1	O60313-1.3	L396H	Pathogenic	0.998
OPA1	O60313-1.3	L396I	Pathogenic	0.902
OPA1	O60313-1.3	L396K	Pathogenic	0.983
OPA1	O60313-1.3	L396M	Pathogenic	0.868
OPA1	O60313-1.3	L396N	Pathogenic	0.996
OPA1	O60313-1.3	L396P	Pathogenic	0.999
OPA1	O60313-1.3	L396Q	Pathogenic	0.992
OPA1	O60313-1.3	L396R	Pathogenic	0.982
OPA1	O60313-1.3	L396S	Pathogenic	0.992
OPA1	O60313-1.3	L396T	Pathogenic	0.983
OPA1	O60313-1.3	L396V	Pathogenic	0.946
OPA1	O60313-1.3	L396W	Pathogenic	0.997
OPA1	O60313-1.3	L396Y	Pathogenic	0.992
OPA1	O60313-1.3	V397A	Pathogenic	0.975
OPA1	O60313-1.3	V397C	Pathogenic	0.996
OPA1	O60313-1.3	V397D	Pathogenic	0.997
OPA1	O60313-1.3	V397E	Pathogenic	0.994
OPA1	O60313-1.3	V397F	Pathogenic	0.994
OPA1	O60313-1.3	V397G	Pathogenic	0.999
OPA1	O60313-1.3	V397H	Pathogenic	0.999
OPA1	O60313-1.3	V397I	Pathogenic	0.7
OPA1	O60313-1.3	V397K	Pathogenic	0.99
OPA1	O60313-1.3	V397L	Pathogenic	0.956
OPA1	O60313-1.3	V397M	Pathogenic	0.971
OPA1	O60313-1.3	V397N	Pathogenic	0.998
OPA1	O60313-1.3	V397P	Pathogenic	0.998
OPA1	O60313-1.3	V397Q	Pathogenic	0.996
OPA1	O60313-1.3	V397R	Pathogenic	0.996
OPA1	O60313-1.3	V397S	Pathogenic	0.996
OPA1	O60313-1.3	V397T	Pathogenic	0.976
OPA1	O60313-1.3	V397W	Pathogenic	0.999
OPA1	O60313-1.3	V397Y	Pathogenic	0.995
OPA1	O60313-1.3	D398A	Pathogenic	0.95
OPA1	O60313-1.3	D398C	Pathogenic	0.97
OPA1	O60313-1.3	D398E	Neutral	0.397
OPA1	O60313-1.3	D398F	Pathogenic	0.93
OPA1	O60313-1.3	D398G	Pathogenic	0.891
OPA1	O60313-1.3	D398H	Pathogenic	0.884
OPA1	O60313-1.3	D398I	Pathogenic	0.932
OPA1	O60313-1.3	D398K	Pathogenic	0.931
OPA1	O60313-1.3	D398L	Pathogenic	0.977
OPA1	O60313-1.3	D398M	Pathogenic	0.958
OPA1	O60313-1.3	D398N	Pathogenic	0.659
OPA1	O60313-1.3	D398P	Pathogenic	0.831
OPA1	O60313-1.3	D398Q	Pathogenic	0.787
OPA1	O60313-1.3	D398R	Pathogenic	0.973
OPA1	O60313-1.3	D398S	Pathogenic	0.761
OPA1	O60313-1.3	D398T	Pathogenic	0.882
OPA1	O60313-1.3	D398V	Pathogenic	0.962
OPA1	O60313-1.3	D398W	Pathogenic	0.958
OPA1	O60313-1.3	D398Y	Pathogenic	0.965
OPA1	O60313-1.3	L399A	Pathogenic	0.889
OPA1	O60313-1.3	L399C	Pathogenic	0.941
OPA1	O60313-1.3	L399D	Pathogenic	0.988
OPA1	O60313-1.3	L399E	Pathogenic	0.971
OPA1	O60313-1.3	L399F	Pathogenic	0.915
OPA1	O60313-1.3	L399G	Pathogenic	0.993
OPA1	O60313-1.3	L399H	Pathogenic	0.986
OPA1	O60313-1.3	L399I	Pathogenic	0.569
OPA1	O60313-1.3	L399K	Pathogenic	0.893
OPA1	O60313-1.3	L399M	Neutral	0.486
OPA1	O60313-1.3	L399N	Pathogenic	0.97
OPA1	O60313-1.3	L399P	Pathogenic	0.991
OPA1	O60313-1.3	L399Q	Pathogenic	0.945
OPA1	O60313-1.3	L399R	Pathogenic	0.887
OPA1	O60313-1.3	L399S	Pathogenic	0.945
OPA1	O60313-1.3	L399T	Pathogenic	0.894
OPA1	O60313-1.3	L399V	Pathogenic	0.716
OPA1	O60313-1.3	L399W	Pathogenic	0.982
OPA1	O60313-1.3	L399Y	Pathogenic	0.944
OPA1	O60313-1.3	P400A	Pathogenic	0.94
OPA1	O60313-1.3	P400C	Pathogenic	0.994
OPA1	O60313-1.3	P400D	Pathogenic	0.863
OPA1	O60313-1.3	P400E	Pathogenic	0.87
OPA1	O60313-1.3	P400F	Pathogenic	0.995
OPA1	O60313-1.3	P400G	Pathogenic	0.97
OPA1	O60313-1.3	P400H	Pathogenic	0.974
OPA1	O60313-1.3	P400I	Pathogenic	0.985
OPA1	O60313-1.3	P400K	Pathogenic	0.814
OPA1	O60313-1.3	P400L	Pathogenic	0.987
OPA1	O60313-1.3	P400M	Pathogenic	0.975
OPA1	O60313-1.3	P400N	Pathogenic	0.955
OPA1	O60313-1.3	P400Q	Pathogenic	0.906
OPA1	O60313-1.3	P400R	Pathogenic	0.923
OPA1	O60313-1.3	P400S	Pathogenic	0.921
OPA1	O60313-1.3	P400T	Pathogenic	0.941
OPA1	O60313-1.3	P400V	Pathogenic	0.977
OPA1	O60313-1.3	P400W	Pathogenic	0.991
OPA1	O60313-1.3	P400Y	Pathogenic	0.993
OPA1	O60313-1.3	G401A	Pathogenic	0.848
OPA1	O60313-1.3	G401C	Pathogenic	0.986
OPA1	O60313-1.3	G401D	Pathogenic	0.907
OPA1	O60313-1.3	G401E	Pathogenic	0.967
OPA1	O60313-1.3	G401F	Pathogenic	0.965
OPA1	O60313-1.3	G401H	Pathogenic	0.979
OPA1	O60313-1.3	G401I	Pathogenic	0.988
OPA1	O60313-1.3	G401K	Pathogenic	0.951
OPA1	O60313-1.3	G401L	Pathogenic	0.989
OPA1	O60313-1.3	G401M	Pathogenic	0.979
OPA1	O60313-1.3	G401N	Pathogenic	0.793
OPA1	O60313-1.3	G401P	Pathogenic	0.967
OPA1	O60313-1.3	G401Q	Pathogenic	0.977
OPA1	O60313-1.3	G401R	Pathogenic	0.948
OPA1	O60313-1.3	G401S	Pathogenic	0.875
OPA1	O60313-1.3	G401T	Pathogenic	0.978
OPA1	O60313-1.3	G401V	Pathogenic	0.981
OPA1	O60313-1.3	G401W	Pathogenic	0.847
OPA1	O60313-1.3	G401Y	Pathogenic	0.983
OPA1	O60313-1.3	V402A	Neutral	0.145
OPA1	O60313-1.3	V402C	Neutral	0.494
OPA1	O60313-1.3	V402D	Pathogenic	0.627
OPA1	O60313-1.3	V402E	Neutral	0.404
OPA1	O60313-1.3	V402F	Neutral	0.407
OPA1	O60313-1.3	V402G	Pathogenic	0.743
OPA1	O60313-1.3	V402H	Pathogenic	0.794
OPA1	O60313-1.3	V402I	Neutral	0.01
OPA1	O60313-1.3	V402K	Neutral	0.309
OPA1	O60313-1.3	V402L	Neutral	0.085
OPA1	O60313-1.3	V402M	Neutral	0.124
OPA1	O60313-1.3	V402N	Pathogenic	0.666
OPA1	O60313-1.3	V402P	Pathogenic	0.693
OPA1	O60313-1.3	V402Q	Neutral	0.494
OPA1	O60313-1.3	V402R	Pathogenic	0.549
OPA1	O60313-1.3	V402S	Pathogenic	0.515
OPA1	O60313-1.3	V402T	Neutral	0.151
OPA1	O60313-1.3	V402W	Pathogenic	0.773
OPA1	O60313-1.3	V402Y	Neutral	0.473
OPA1	O60313-1.3	I403A	Pathogenic	0.967
OPA1	O60313-1.3	I403C	Pathogenic	0.983
OPA1	O60313-1.3	I403D	Pathogenic	0.99
OPA1	O60313-1.3	I403E	Pathogenic	0.992
OPA1	O60313-1.3	I403F	Pathogenic	0.979
OPA1	O60313-1.3	I403G	Pathogenic	0.998
OPA1	O60313-1.3	I403H	Pathogenic	0.996
OPA1	O60313-1.3	I403K	Pathogenic	0.989
OPA1	O60313-1.3	I403L	Pathogenic	0.842
OPA1	O60313-1.3	I403M	Pathogenic	0.91
OPA1	O60313-1.3	I403N	Pathogenic	0.992
OPA1	O60313-1.3	I403P	Pathogenic	0.997
OPA1	O60313-1.3	I403Q	Pathogenic	0.995
OPA1	O60313-1.3	I403R	Pathogenic	0.988
OPA1	O60313-1.3	I403S	Pathogenic	0.985
OPA1	O60313-1.3	I403T	Pathogenic	0.969
OPA1	O60313-1.3	I403V	Pathogenic	0.524
OPA1	O60313-1.3	I403W	Pathogenic	0.999
OPA1	O60313-1.3	I403Y	Pathogenic	0.984
OPA1	O60313-1.3	N404A	Pathogenic	0.776
OPA1	O60313-1.3	N404C	Pathogenic	0.853
OPA1	O60313-1.3	N404D	Neutral	0.235
OPA1	O60313-1.3	N404E	Neutral	0.493
OPA1	O60313-1.3	N404F	Pathogenic	0.714
OPA1	O60313-1.3	N404G	Neutral	0.338
OPA1	O60313-1.3	N404H	Neutral	0.147
OPA1	O60313-1.3	N404I	Pathogenic	0.72
OPA1	O60313-1.3	N404K	Neutral	0.39
OPA1	O60313-1.3	N404L	Pathogenic	0.738
OPA1	O60313-1.3	N404M	Pathogenic	0.599
OPA1	O60313-1.3	N404P	Pathogenic	0.722
OPA1	O60313-1.3	N404Q	Neutral	0.411
OPA1	O60313-1.3	N404R	Neutral	0.376
OPA1	O60313-1.3	N404S	Neutral	0.166
OPA1	O60313-1.3	N404T	Neutral	0.323
OPA1	O60313-1.3	N404V	Pathogenic	0.825
OPA1	O60313-1.3	N404W	Pathogenic	0.81
OPA1	O60313-1.3	N404Y	Pathogenic	0.643
OPA1	O60313-1.3	T405A	Pathogenic	0.977
OPA1	O60313-1.3	T405C	Pathogenic	0.986
OPA1	O60313-1.3	T405D	Pathogenic	0.982
OPA1	O60313-1.3	T405E	Pathogenic	0.983
OPA1	O60313-1.3	T405F	Pathogenic	0.989
OPA1	O60313-1.3	T405G	Pathogenic	0.996
OPA1	O60313-1.3	T405H	Pathogenic	0.997
OPA1	O60313-1.3	T405I	Pathogenic	0.969
OPA1	O60313-1.3	T405K	Pathogenic	0.975
OPA1	O60313-1.3	T405L	Pathogenic	0.971
OPA1	O60313-1.3	T405M	Pathogenic	0.981
OPA1	O60313-1.3	T405N	Pathogenic	0.957
OPA1	O60313-1.3	T405P	Pathogenic	0.989
OPA1	O60313-1.3	T405Q	Pathogenic	0.988
OPA1	O60313-1.3	T405R	Pathogenic	0.973
OPA1	O60313-1.3	T405S	Pathogenic	0.923
OPA1	O60313-1.3	T405V	Pathogenic	0.951
OPA1	O60313-1.3	T405W	Pathogenic	0.981
OPA1	O60313-1.3	T405Y	Pathogenic	0.995
OPA1	O60313-1.3	V406A	Pathogenic	0.674
OPA1	O60313-1.3	V406C	Pathogenic	0.923
OPA1	O60313-1.3	V406D	Pathogenic	0.954
OPA1	O60313-1.3	V406E	Pathogenic	0.892
OPA1	O60313-1.3	V406F	Pathogenic	0.894
OPA1	O60313-1.3	V406G	Pathogenic	0.973
OPA1	O60313-1.3	V406H	Pathogenic	0.979
OPA1	O60313-1.3	V406I	Neutral	0.109
OPA1	O60313-1.3	V406K	Pathogenic	0.845
OPA1	O60313-1.3	V406L	Pathogenic	0.53
OPA1	O60313-1.3	V406M	Pathogenic	0.634
OPA1	O60313-1.3	V406N	Pathogenic	0.961
OPA1	O60313-1.3	V406P	Pathogenic	0.965
OPA1	O60313-1.3	V406Q	Pathogenic	0.923
OPA1	O60313-1.3	V406R	Pathogenic	0.937
OPA1	O60313-1.3	V406S	Pathogenic	0.928
OPA1	O60313-1.3	V406T	Pathogenic	0.685
OPA1	O60313-1.3	V406W	Pathogenic	0.977
OPA1	O60313-1.3	V406Y	Pathogenic	0.916
OPA1	O60313-1.3	T407A	Pathogenic	0.977
OPA1	O60313-1.3	T407C	Pathogenic	0.986
OPA1	O60313-1.3	T407D	Pathogenic	0.982
OPA1	O60313-1.3	T407E	Pathogenic	0.983
OPA1	O60313-1.3	T407F	Pathogenic	0.989
OPA1	O60313-1.3	T407G	Pathogenic	0.996
OPA1	O60313-1.3	T407H	Pathogenic	0.997
OPA1	O60313-1.3	T407I	Pathogenic	0.969
OPA1	O60313-1.3	T407K	Pathogenic	0.975
OPA1	O60313-1.3	T407L	Pathogenic	0.971
OPA1	O60313-1.3	T407M	Pathogenic	0.981
OPA1	O60313-1.3	T407N	Pathogenic	0.957
OPA1	O60313-1.3	T407P	Pathogenic	0.989
OPA1	O60313-1.3	T407Q	Pathogenic	0.988
OPA1	O60313-1.3	T407R	Pathogenic	0.973
OPA1	O60313-1.3	T407S	Pathogenic	0.923
OPA1	O60313-1.3	T407V	Pathogenic	0.951
OPA1	O60313-1.3	T407W	Pathogenic	0.981
OPA1	O60313-1.3	T407Y	Pathogenic	0.995
OPA1	O60313-1.3	S408A	Neutral	0.025
OPA1	O60313-1.3	S408C	Neutral	0.103
OPA1	O60313-1.3	S408D	Neutral	0.048
OPA1	O60313-1.3	S408E	Neutral	0.051
OPA1	O60313-1.3	S408F	Neutral	0.117
OPA1	O60313-1.3	S408G	Neutral	0.085
OPA1	O60313-1.3	S408H	Neutral	0.182
OPA1	O60313-1.3	S408I	Neutral	0.12
OPA1	O60313-1.3	S408K	Neutral	0.034
OPA1	O60313-1.3	S408L	Neutral	0.13
OPA1	O60313-1.3	S408M	Neutral	0.074
OPA1	O60313-1.3	S408N	Neutral	0.02
OPA1	O60313-1.3	S408P	Neutral	0.126
OPA1	O60313-1.3	S408Q	Neutral	0.071
OPA1	O60313-1.3	S408R	Neutral	0.087
OPA1	O60313-1.3	S408T	Neutral	0.025
OPA1	O60313-1.3	S408V	Neutral	0.201
OPA1	O60313-1.3	S408W	Neutral	0.185
OPA1	O60313-1.3	S408Y	Neutral	0.217
OPA1	O60313-1.3	G409A	Pathogenic	0.781
OPA1	O60313-1.3	G409C	Pathogenic	0.978
OPA1	O60313-1.3	G409D	Pathogenic	0.861
OPA1	O60313-1.3	G409E	Pathogenic	0.95
OPA1	O60313-1.3	G409F	Pathogenic	0.945
OPA1	O60313-1.3	G409H	Pathogenic	0.967
OPA1	O60313-1.3	G409I	Pathogenic	0.981
OPA1	O60313-1.3	G409K	Pathogenic	0.926
OPA1	O60313-1.3	G409L	Pathogenic	0.983
OPA1	O60313-1.3	G409M	Pathogenic	0.968
OPA1	O60313-1.3	G409N	Pathogenic	0.709
OPA1	O60313-1.3	G409P	Pathogenic	0.95
OPA1	O60313-1.3	G409Q	Pathogenic	0.965
OPA1	O60313-1.3	G409R	Pathogenic	0.921
OPA1	O60313-1.3	G409S	Pathogenic	0.817
OPA1	O60313-1.3	G409T	Pathogenic	0.966
OPA1	O60313-1.3	G409V	Pathogenic	0.97
OPA1	O60313-1.3	G409W	Pathogenic	0.779
OPA1	O60313-1.3	G409Y	Pathogenic	0.973
OPA1	O60313-1.3	M410A	Pathogenic	0.994
OPA1	O60313-1.3	M410C	Pathogenic	0.997
OPA1	O60313-1.3	M410D	Pathogenic	0.998
OPA1	O60313-1.3	M410E	Pathogenic	0.996
OPA1	O60313-1.3	M410F	Pathogenic	0.989
OPA1	O60313-1.3	M410G	Pathogenic	0.999
OPA1	O60313-1.3	M410H	Pathogenic	0.998
OPA1	O60313-1.3	M410I	Pathogenic	0.97
OPA1	O60313-1.3	M410K	Pathogenic	0.983
OPA1	O60313-1.3	M410L	Pathogenic	0.925
OPA1	O60313-1.3	M410N	Pathogenic	0.996
OPA1	O60313-1.3	M410P	Pathogenic	0.999
OPA1	O60313-1.3	M410Q	Pathogenic	0.976
OPA1	O60313-1.3	M410R	Pathogenic	0.982
OPA1	O60313-1.3	M410S	Pathogenic	0.992
OPA1	O60313-1.3	M410T	Pathogenic	0.994
OPA1	O60313-1.3	M410V	Pathogenic	0.981
OPA1	O60313-1.3	M410W	Pathogenic	0.994
OPA1	O60313-1.3	M410Y	Pathogenic	0.997
OPA1	O60313-1.3	A411C	Pathogenic	0.982
OPA1	O60313-1.3	A411D	Pathogenic	0.997
OPA1	O60313-1.3	A411E	Pathogenic	0.991
OPA1	O60313-1.3	A411F	Pathogenic	0.995
OPA1	O60313-1.3	A411G	Pathogenic	0.987
OPA1	O60313-1.3	A411H	Pathogenic	0.998
OPA1	O60313-1.3	A411I	Pathogenic	0.985
OPA1	O60313-1.3	A411K	Pathogenic	0.987
OPA1	O60313-1.3	A411L	Pathogenic	0.986
OPA1	O60313-1.3	A411M	Pathogenic	0.991
OPA1	O60313-1.3	A411N	Pathogenic	0.997
OPA1	O60313-1.3	A411P	Pathogenic	0.995
OPA1	O60313-1.3	A411Q	Pathogenic	0.994
OPA1	O60313-1.3	A411R	Pathogenic	0.986
OPA1	O60313-1.3	A411S	Pathogenic	0.964
OPA1	O60313-1.3	A411T	Pathogenic	0.99
OPA1	O60313-1.3	A411V	Pathogenic	0.976
OPA1	O60313-1.3	A411W	Pathogenic	0.997
OPA1	O60313-1.3	A411Y	Pathogenic	0.997
OPA1	O60313-1.3	P412A	Neutral	0.326
OPA1	O60313-1.3	P412C	Pathogenic	0.833
OPA1	O60313-1.3	P412D	Neutral	0.164
OPA1	O60313-1.3	P412E	Neutral	0.171
OPA1	O60313-1.3	P412F	Pathogenic	0.856
OPA1	O60313-1.3	P412G	Neutral	0.496
OPA1	O60313-1.3	P412H	Pathogenic	0.539
OPA1	O60313-1.3	P412I	Pathogenic	0.678
OPA1	O60313-1.3	P412K	Neutral	0.12
OPA1	O60313-1.3	P412L	Pathogenic	0.698
OPA1	O60313-1.3	P412M	Pathogenic	0.55
OPA1	O60313-1.3	P412N	Neutral	0.394
OPA1	O60313-1.3	P412Q	Neutral	0.229
OPA1	O60313-1.3	P412R	Neutral	0.27
OPA1	O60313-1.3	P412S	Neutral	0.265
OPA1	O60313-1.3	P412T	Neutral	0.332
OPA1	O60313-1.3	P412V	Pathogenic	0.571
OPA1	O60313-1.3	P412W	Pathogenic	0.778
OPA1	O60313-1.3	P412Y	Pathogenic	0.81
OPA1	O60313-1.3	D413A	Pathogenic	0.992
OPA1	O60313-1.3	D413C	Pathogenic	0.995
OPA1	O60313-1.3	D413E	Pathogenic	0.814
OPA1	O60313-1.3	D413F	Pathogenic	0.989
OPA1	O60313-1.3	D413G	Pathogenic	0.982
OPA1	O60313-1.3	D413H	Pathogenic	0.981
OPA1	O60313-1.3	D413I	Pathogenic	0.989
OPA1	O60313-1.3	D413K	Pathogenic	0.989
OPA1	O60313-1.3	D413L	Pathogenic	0.997
OPA1	O60313-1.3	D413M	Pathogenic	0.994
OPA1	O60313-1.3	D413N	Pathogenic	0.928
OPA1	O60313-1.3	D413P	Pathogenic	0.97
OPA1	O60313-1.3	D413Q	Pathogenic	0.961
OPA1	O60313-1.3	D413R	Pathogenic	0.996
OPA1	O60313-1.3	D413S	Pathogenic	0.955
OPA1	O60313-1.3	D413T	Pathogenic	0.98
OPA1	O60313-1.3	D413V	Pathogenic	0.994
OPA1	O60313-1.3	D413W	Pathogenic	0.993
OPA1	O60313-1.3	D413Y	Pathogenic	0.995
OPA1	O60313-1.3	T414A	Pathogenic	0.99
OPA1	O60313-1.3	T414C	Pathogenic	0.994
OPA1	O60313-1.3	T414D	Pathogenic	0.992
OPA1	O60313-1.3	T414E	Pathogenic	0.993
OPA1	O60313-1.3	T414F	Pathogenic	0.995
OPA1	O60313-1.3	T414G	Pathogenic	0.998
OPA1	O60313-1.3	T414H	Pathogenic	0.999
OPA1	O60313-1.3	T414I	Pathogenic	0.986
OPA1	O60313-1.3	T414K	Pathogenic	0.989
OPA1	O60313-1.3	T414L	Pathogenic	0.987
OPA1	O60313-1.3	T414M	Pathogenic	0.992
OPA1	O60313-1.3	T414N	Pathogenic	0.981
OPA1	O60313-1.3	T414P	Pathogenic	0.995
OPA1	O60313-1.3	T414Q	Pathogenic	0.995
OPA1	O60313-1.3	T414R	Pathogenic	0.988
OPA1	O60313-1.3	T414S	Pathogenic	0.965
OPA1	O60313-1.3	T414V	Pathogenic	0.978
OPA1	O60313-1.3	T414W	Pathogenic	0.992
OPA1	O60313-1.3	T414Y	Pathogenic	0.998
OPA1	O60313-1.3	K415A	Pathogenic	0.872
OPA1	O60313-1.3	K415C	Pathogenic	0.971
OPA1	O60313-1.3	K415D	Pathogenic	0.952
OPA1	O60313-1.3	K415E	Pathogenic	0.692
OPA1	O60313-1.3	K415F	Pathogenic	0.95
OPA1	O60313-1.3	K415G	Pathogenic	0.96
OPA1	O60313-1.3	K415H	Pathogenic	0.906
OPA1	O60313-1.3	K415I	Pathogenic	0.947
OPA1	O60313-1.3	K415L	Pathogenic	0.872
OPA1	O60313-1.3	K415M	Pathogenic	0.783
OPA1	O60313-1.3	K415N	Pathogenic	0.857
OPA1	O60313-1.3	K415P	Pathogenic	0.836
OPA1	O60313-1.3	K415Q	Pathogenic	0.61
OPA1	O60313-1.3	K415R	Pathogenic	0.525
OPA1	O60313-1.3	K415S	Pathogenic	0.767
OPA1	O60313-1.3	K415T	Pathogenic	0.887
OPA1	O60313-1.3	K415V	Pathogenic	0.908
OPA1	O60313-1.3	K415W	Pathogenic	0.918
OPA1	O60313-1.3	K415Y	Pathogenic	0.932
OPA1	O60313-1.3	E416A	Pathogenic	0.918
OPA1	O60313-1.3	E416C	Pathogenic	0.994
OPA1	O60313-1.3	E416D	Pathogenic	0.515
OPA1	O60313-1.3	E416F	Pathogenic	0.963
OPA1	O60313-1.3	E416G	Pathogenic	0.976
OPA1	O60313-1.3	E416H	Pathogenic	0.837
OPA1	O60313-1.3	E416I	Pathogenic	0.964
OPA1	O60313-1.3	E416K	Pathogenic	0.71
OPA1	O60313-1.3	E416L	Pathogenic	0.967
OPA1	O60313-1.3	E416M	Pathogenic	0.939
OPA1	O60313-1.3	E416N	Pathogenic	0.908
OPA1	O60313-1.3	E416P	Pathogenic	0.894
OPA1	O60313-1.3	E416Q	Neutral	0.462
OPA1	O60313-1.3	E416R	Pathogenic	0.869
OPA1	O60313-1.3	E416S	Pathogenic	0.845
OPA1	O60313-1.3	E416T	Pathogenic	0.928
OPA1	O60313-1.3	E416V	Pathogenic	0.942
OPA1	O60313-1.3	E416W	Pathogenic	0.938
OPA1	O60313-1.3	E416Y	Pathogenic	0.949
OPA1	O60313-1.3	T417A	Pathogenic	0.704
OPA1	O60313-1.3	T417C	Pathogenic	0.8
OPA1	O60313-1.3	T417D	Pathogenic	0.756
OPA1	O60313-1.3	T417E	Pathogenic	0.768
OPA1	O60313-1.3	T417F	Pathogenic	0.829
OPA1	O60313-1.3	T417G	Pathogenic	0.939
OPA1	O60313-1.3	T417H	Pathogenic	0.949
OPA1	O60313-1.3	T417I	Pathogenic	0.633
OPA1	O60313-1.3	T417K	Pathogenic	0.685
OPA1	O60313-1.3	T417L	Pathogenic	0.654
OPA1	O60313-1.3	T417M	Pathogenic	0.744
OPA1	O60313-1.3	T417N	Pathogenic	0.553
OPA1	O60313-1.3	T417P	Pathogenic	0.838
OPA1	O60313-1.3	T417Q	Pathogenic	0.826
OPA1	O60313-1.3	T417R	Pathogenic	0.672
OPA1	O60313-1.3	T417S	Neutral	0.402
OPA1	O60313-1.3	T417V	Pathogenic	0.522
OPA1	O60313-1.3	T417W	Pathogenic	0.741
OPA1	O60313-1.3	T417Y	Pathogenic	0.91
OPA1	O60313-1.3	I418A	Pathogenic	0.985
OPA1	O60313-1.3	I418C	Pathogenic	0.993
OPA1	O60313-1.3	I418D	Pathogenic	0.996
OPA1	O60313-1.3	I418E	Pathogenic	0.996
OPA1	O60313-1.3	I418F	Pathogenic	0.991
OPA1	O60313-1.3	I418G	Pathogenic	0.999
OPA1	O60313-1.3	I418H	Pathogenic	0.998
OPA1	O60313-1.3	I418K	Pathogenic	0.995
OPA1	O60313-1.3	I418L	Pathogenic	0.925
OPA1	O60313-1.3	I418M	Pathogenic	0.959
OPA1	O60313-1.3	I418N	Pathogenic	0.996
OPA1	O60313-1.3	I418P	Pathogenic	0.999
OPA1	O60313-1.3	I418Q	Pathogenic	0.998
OPA1	O60313-1.3	I418R	Pathogenic	0.995
OPA1	O60313-1.3	I418S	Pathogenic	0.993
OPA1	O60313-1.3	I418T	Pathogenic	0.986
OPA1	O60313-1.3	I418V	Pathogenic	0.717
OPA1	O60313-1.3	I418W	Pathogenic	0.999
OPA1	O60313-1.3	I418Y	Pathogenic	0.993
OPA1	O60313-1.3	F419A	Pathogenic	0.854
OPA1	O60313-1.3	F419C	Pathogenic	0.921
OPA1	O60313-1.3	F419D	Pathogenic	0.874
OPA1	O60313-1.3	F419E	Pathogenic	0.893
OPA1	O60313-1.3	F419G	Pathogenic	0.923
OPA1	O60313-1.3	F419H	Pathogenic	0.675
OPA1	O60313-1.3	F419I	Pathogenic	0.767
OPA1	O60313-1.3	F419K	Pathogenic	0.87
OPA1	O60313-1.3	F419L	Pathogenic	0.755
OPA1	O60313-1.3	F419M	Pathogenic	0.667
OPA1	O60313-1.3	F419N	Pathogenic	0.892
OPA1	O60313-1.3	F419P	Pathogenic	0.987
OPA1	O60313-1.3	F419Q	Pathogenic	0.926
OPA1	O60313-1.3	F419R	Pathogenic	0.862
OPA1	O60313-1.3	F419S	Pathogenic	0.814
OPA1	O60313-1.3	F419T	Pathogenic	0.86
OPA1	O60313-1.3	F419V	Pathogenic	0.842
OPA1	O60313-1.3	F419W	Neutral	0.415
OPA1	O60313-1.3	F419Y	Neutral	0.061
OPA1	O60313-1.3	S420A	Neutral	0.201
OPA1	O60313-1.3	S420C	Pathogenic	0.527
OPA1	O60313-1.3	S420D	Neutral	0.329
OPA1	O60313-1.3	S420E	Neutral	0.341
OPA1	O60313-1.3	S420F	Pathogenic	0.562
OPA1	O60313-1.3	S420G	Neutral	0.474
OPA1	O60313-1.3	S420H	Pathogenic	0.683
OPA1	O60313-1.3	S420I	Pathogenic	0.569
OPA1	O60313-1.3	S420K	Neutral	0.254
OPA1	O60313-1.3	S420L	Pathogenic	0.592
OPA1	O60313-1.3	S420M	Neutral	0.435
OPA1	O60313-1.3	S420N	Neutral	0.162
OPA1	O60313-1.3	S420P	Pathogenic	0.583
OPA1	O60313-1.3	S420Q	Neutral	0.426
OPA1	O60313-1.3	S420R	Neutral	0.481
OPA1	O60313-1.3	S420T	Neutral	0.201
OPA1	O60313-1.3	S420V	Pathogenic	0.708
OPA1	O60313-1.3	S420W	Pathogenic	0.687
OPA1	O60313-1.3	S420Y	Pathogenic	0.728
OPA1	O60313-1.3	I421A	Pathogenic	0.613
OPA1	O60313-1.3	I421C	Pathogenic	0.759
OPA1	O60313-1.3	I421D	Pathogenic	0.844
OPA1	O60313-1.3	I421E	Pathogenic	0.867
OPA1	O60313-1.3	I421F	Pathogenic	0.715
OPA1	O60313-1.3	I421G	Pathogenic	0.964
OPA1	O60313-1.3	I421H	Pathogenic	0.932
OPA1	O60313-1.3	I421K	Pathogenic	0.828
OPA1	O60313-1.3	I421L	Neutral	0.223
OPA1	O60313-1.3	I421M	Neutral	0.352
OPA1	O60313-1.3	I421N	Pathogenic	0.866
OPA1	O60313-1.3	I421P	Pathogenic	0.955
OPA1	O60313-1.3	I421Q	Pathogenic	0.907
OPA1	O60313-1.3	I421R	Pathogenic	0.819
OPA1	O60313-1.3	I421S	Pathogenic	0.774
OPA1	O60313-1.3	I421T	Pathogenic	0.624
OPA1	O60313-1.3	I421V	Neutral	0.056
OPA1	O60313-1.3	I421W	Pathogenic	0.974
OPA1	O60313-1.3	I421Y	Pathogenic	0.769
OPA1	O60313-1.3	S422A	Pathogenic	0.758
OPA1	O60313-1.3	S422C	Pathogenic	0.933
OPA1	O60313-1.3	S422D	Pathogenic	0.859
OPA1	O60313-1.3	S422E	Pathogenic	0.865
OPA1	O60313-1.3	S422F	Pathogenic	0.941
OPA1	O60313-1.3	S422G	Pathogenic	0.918
OPA1	O60313-1.3	S422H	Pathogenic	0.964
OPA1	O60313-1.3	S422I	Pathogenic	0.943
OPA1	O60313-1.3	S422K	Pathogenic	0.809
OPA1	O60313-1.3	S422L	Pathogenic	0.948
OPA1	O60313-1.3	S422M	Pathogenic	0.905
OPA1	O60313-1.3	S422N	Pathogenic	0.707
OPA1	O60313-1.3	S422P	Pathogenic	0.946
OPA1	O60313-1.3	S422Q	Pathogenic	0.902
OPA1	O60313-1.3	S422R	Pathogenic	0.92
OPA1	O60313-1.3	S422T	Pathogenic	0.757
OPA1	O60313-1.3	S422V	Pathogenic	0.968
OPA1	O60313-1.3	S422W	Pathogenic	0.965
OPA1	O60313-1.3	S422Y	Pathogenic	0.971
OPA1	O60313-1.3	K423A	Pathogenic	0.724
OPA1	O60313-1.3	K423C	Pathogenic	0.927
OPA1	O60313-1.3	K423D	Pathogenic	0.885
OPA1	O60313-1.3	K423E	Neutral	0.464
OPA1	O60313-1.3	K423F	Pathogenic	0.88
OPA1	O60313-1.3	K423G	Pathogenic	0.904
OPA1	O60313-1.3	K423H	Pathogenic	0.788
OPA1	O60313-1.3	K423I	Pathogenic	0.874
OPA1	O60313-1.3	K423L	Pathogenic	0.724
OPA1	O60313-1.3	K423M	Pathogenic	0.582
OPA1	O60313-1.3	K423N	Pathogenic	0.698
OPA1	O60313-1.3	K423P	Pathogenic	0.662
OPA1	O60313-1.3	K423Q	Neutral	0.376
OPA1	O60313-1.3	K423R	Neutral	0.299
OPA1	O60313-1.3	K423S	Pathogenic	0.559
OPA1	O60313-1.3	K423T	Pathogenic	0.751
OPA1	O60313-1.3	K423V	Pathogenic	0.792
OPA1	O60313-1.3	K423W	Pathogenic	0.812
OPA1	O60313-1.3	K423Y	Pathogenic	0.84
OPA1	O60313-1.3	A424C	Neutral	0.329
OPA1	O60313-1.3	A424D	Pathogenic	0.736
OPA1	O60313-1.3	A424E	Pathogenic	0.504
OPA1	O60313-1.3	A424F	Pathogenic	0.621
OPA1	O60313-1.3	A424G	Neutral	0.406
OPA1	O60313-1.3	A424H	Pathogenic	0.852
OPA1	O60313-1.3	A424I	Neutral	0.367
OPA1	O60313-1.3	A424K	Neutral	0.401
OPA1	O60313-1.3	A424L	Neutral	0.39
OPA1	O60313-1.3	A424M	Neutral	0.495
OPA1	O60313-1.3	A424N	Pathogenic	0.762
OPA1	O60313-1.3	A424P	Pathogenic	0.64
OPA1	O60313-1.3	A424Q	Pathogenic	0.594
OPA1	O60313-1.3	A424R	Neutral	0.386
OPA1	O60313-1.3	A424S	Neutral	0.193
OPA1	O60313-1.3	A424T	Neutral	0.458
OPA1	O60313-1.3	A424V	Neutral	0.269
OPA1	O60313-1.3	A424W	Pathogenic	0.737
OPA1	O60313-1.3	A424Y	Pathogenic	0.774
OPA1	O60313-1.3	Y425A	Pathogenic	0.998
OPA1	O60313-1.3	Y425C	Pathogenic	0.999
OPA1	O60313-1.3	Y425D	Pathogenic	0.998
OPA1	O60313-1.3	Y425E	Pathogenic	0.996
OPA1	O60313-1.3	Y425F	Pathogenic	0.742
OPA1	O60313-1.3	Y425G	Pathogenic	0.999
OPA1	O60313-1.3	Y425H	Pathogenic	0.887
OPA1	O60313-1.3	Y425I	Pathogenic	0.995
OPA1	O60313-1.3	Y425K	Pathogenic	0.995
OPA1	O60313-1.3	Y425L	Pathogenic	0.995
OPA1	O60313-1.3	Y425M	Pathogenic	0.997
OPA1	O60313-1.3	Y425N	Pathogenic	0.996
OPA1	O60313-1.3	Y425P	Pathogenic	1.0
OPA1	O60313-1.3	Y425Q	Pathogenic	0.993
OPA1	O60313-1.3	Y425R	Pathogenic	0.995
OPA1	O60313-1.3	Y425S	Pathogenic	0.998
OPA1	O60313-1.3	Y425T	Pathogenic	0.998
OPA1	O60313-1.3	Y425V	Pathogenic	0.997
OPA1	O60313-1.3	Y425W	Pathogenic	0.837
OPA1	O60313-1.3	M426A	Pathogenic	0.994
OPA1	O60313-1.3	M426C	Pathogenic	0.997
OPA1	O60313-1.3	M426D	Pathogenic	0.998
OPA1	O60313-1.3	M426E	Pathogenic	0.996
OPA1	O60313-1.3	M426F	Pathogenic	0.989
OPA1	O60313-1.3	M426G	Pathogenic	0.999
OPA1	O60313-1.3	M426H	Pathogenic	0.998
OPA1	O60313-1.3	M426I	Pathogenic	0.97
OPA1	O60313-1.3	M426K	Pathogenic	0.983
OPA1	O60313-1.3	M426L	Pathogenic	0.925
OPA1	O60313-1.3	M426N	Pathogenic	0.996
OPA1	O60313-1.3	M426P	Pathogenic	0.999
OPA1	O60313-1.3	M426Q	Pathogenic	0.976
OPA1	O60313-1.3	M426R	Pathogenic	0.982
OPA1	O60313-1.3	M426S	Pathogenic	0.992
OPA1	O60313-1.3	M426T	Pathogenic	0.994
OPA1	O60313-1.3	M426V	Pathogenic	0.981
OPA1	O60313-1.3	M426W	Pathogenic	0.994
OPA1	O60313-1.3	M426Y	Pathogenic	0.997
OPA1	O60313-1.3	Q427A	Pathogenic	0.867
OPA1	O60313-1.3	Q427C	Pathogenic	0.969
OPA1	O60313-1.3	Q427D	Pathogenic	0.707
OPA1	O60313-1.3	Q427E	Neutral	0.257
OPA1	O60313-1.3	Q427F	Pathogenic	0.94
OPA1	O60313-1.3	Q427G	Pathogenic	0.959
OPA1	O60313-1.3	Q427H	Pathogenic	0.756
OPA1	O60313-1.3	Q427I	Pathogenic	0.941
OPA1	O60313-1.3	Q427K	Neutral	0.407
OPA1	O60313-1.3	Q427L	Pathogenic	0.859
OPA1	O60313-1.3	Q427M	Pathogenic	0.526
OPA1	O60313-1.3	Q427N	Pathogenic	0.741
OPA1	O60313-1.3	Q427P	Pathogenic	0.83
OPA1	O60313-1.3	Q427R	Neutral	0.392
OPA1	O60313-1.3	Q427S	Pathogenic	0.759
OPA1	O60313-1.3	Q427T	Pathogenic	0.883
OPA1	O60313-1.3	Q427V	Pathogenic	0.905
OPA1	O60313-1.3	Q427W	Pathogenic	0.76
OPA1	O60313-1.3	Q427Y	Pathogenic	0.795
OPA1	O60313-1.3	N428A	Pathogenic	0.998
OPA1	O60313-1.3	N428C	Pathogenic	0.999
OPA1	O60313-1.3	N428D	Pathogenic	0.974
OPA1	O60313-1.3	N428E	Pathogenic	0.992
OPA1	O60313-1.3	N428F	Pathogenic	0.997
OPA1	O60313-1.3	N428G	Pathogenic	0.984
OPA1	O60313-1.3	N428H	Pathogenic	0.954
OPA1	O60313-1.3	N428I	Pathogenic	0.997
OPA1	O60313-1.3	N428K	Pathogenic	0.987
OPA1	O60313-1.3	N428L	Pathogenic	0.997
OPA1	O60313-1.3	N428M	Pathogenic	0.994
OPA1	O60313-1.3	N428P	Pathogenic	0.997
OPA1	O60313-1.3	N428Q	Pathogenic	0.988
OPA1	O60313-1.3	N428R	Pathogenic	0.986
OPA1	O60313-1.3	N428S	Pathogenic	0.96
OPA1	O60313-1.3	N428T	Pathogenic	0.983
OPA1	O60313-1.3	N428V	Pathogenic	0.998
OPA1	O60313-1.3	N428W	Pathogenic	0.998
OPA1	O60313-1.3	N428Y	Pathogenic	0.995
OPA1	O60313-1.3	P429A	Pathogenic	0.996
OPA1	O60313-1.3	P429C	Pathogenic	1.0
OPA1	O60313-1.3	P429D	Pathogenic	0.99
OPA1	O60313-1.3	P429E	Pathogenic	0.991
OPA1	O60313-1.3	P429F	Pathogenic	1.0
OPA1	O60313-1.3	P429G	Pathogenic	0.998
OPA1	O60313-1.3	P429H	Pathogenic	0.998
OPA1	O60313-1.3	P429I	Pathogenic	0.999
OPA1	O60313-1.3	P429K	Pathogenic	0.986
OPA1	O60313-1.3	P429L	Pathogenic	0.999
OPA1	O60313-1.3	P429M	Pathogenic	0.998
OPA1	O60313-1.3	P429N	Pathogenic	0.997
OPA1	O60313-1.3	P429Q	Pathogenic	0.994
OPA1	O60313-1.3	P429R	Pathogenic	0.995
OPA1	O60313-1.3	P429S	Pathogenic	0.995
OPA1	O60313-1.3	P429T	Pathogenic	0.996
OPA1	O60313-1.3	P429V	Pathogenic	0.999
OPA1	O60313-1.3	P429W	Pathogenic	0.999
OPA1	O60313-1.3	P429Y	Pathogenic	1.0
OPA1	O60313-1.3	N430A	Pathogenic	0.998
OPA1	O60313-1.3	N430C	Pathogenic	0.999
OPA1	O60313-1.3	N430D	Pathogenic	0.974
OPA1	O60313-1.3	N430E	Pathogenic	0.992
OPA1	O60313-1.3	N430F	Pathogenic	0.997
OPA1	O60313-1.3	N430G	Pathogenic	0.984
OPA1	O60313-1.3	N430H	Pathogenic	0.954
OPA1	O60313-1.3	N430I	Pathogenic	0.997
OPA1	O60313-1.3	N430K	Pathogenic	0.987
OPA1	O60313-1.3	N430L	Pathogenic	0.997
OPA1	O60313-1.3	N430M	Pathogenic	0.994
OPA1	O60313-1.3	N430P	Pathogenic	0.997
OPA1	O60313-1.3	N430Q	Pathogenic	0.988
OPA1	O60313-1.3	N430R	Pathogenic	0.986
OPA1	O60313-1.3	N430S	Pathogenic	0.96
OPA1	O60313-1.3	N430T	Pathogenic	0.983
OPA1	O60313-1.3	N430V	Pathogenic	0.998
OPA1	O60313-1.3	N430W	Pathogenic	0.998
OPA1	O60313-1.3	N430Y	Pathogenic	0.995
OPA1	O60313-1.3	A431C	Pathogenic	0.982
OPA1	O60313-1.3	A431D	Pathogenic	0.997
OPA1	O60313-1.3	A431E	Pathogenic	0.991
OPA1	O60313-1.3	A431F	Pathogenic	0.995
OPA1	O60313-1.3	A431G	Pathogenic	0.987
OPA1	O60313-1.3	A431H	Pathogenic	0.998
OPA1	O60313-1.3	A431I	Pathogenic	0.985
OPA1	O60313-1.3	A431K	Pathogenic	0.987
OPA1	O60313-1.3	A431L	Pathogenic	0.986
OPA1	O60313-1.3	A431M	Pathogenic	0.991
OPA1	O60313-1.3	A431N	Pathogenic	0.997
OPA1	O60313-1.3	A431P	Pathogenic	0.995
OPA1	O60313-1.3	A431Q	Pathogenic	0.994
OPA1	O60313-1.3	A431R	Pathogenic	0.986
OPA1	O60313-1.3	A431S	Pathogenic	0.964
OPA1	O60313-1.3	A431T	Pathogenic	0.99
OPA1	O60313-1.3	A431V	Pathogenic	0.976
OPA1	O60313-1.3	A431W	Pathogenic	0.997
OPA1	O60313-1.3	A431Y	Pathogenic	0.997
OPA1	O60313-1.3	I432A	Pathogenic	0.985
OPA1	O60313-1.3	I432C	Pathogenic	0.993
OPA1	O60313-1.3	I432D	Pathogenic	0.996
OPA1	O60313-1.3	I432E	Pathogenic	0.996
OPA1	O60313-1.3	I432F	Pathogenic	0.991
OPA1	O60313-1.3	I432G	Pathogenic	0.999
OPA1	O60313-1.3	I432H	Pathogenic	0.998
OPA1	O60313-1.3	I432K	Pathogenic	0.995
OPA1	O60313-1.3	I432L	Pathogenic	0.925
OPA1	O60313-1.3	I432M	Pathogenic	0.959
OPA1	O60313-1.3	I432N	Pathogenic	0.996
OPA1	O60313-1.3	I432P	Pathogenic	0.999
OPA1	O60313-1.3	I432Q	Pathogenic	0.998
OPA1	O60313-1.3	I432R	Pathogenic	0.995
OPA1	O60313-1.3	I432S	Pathogenic	0.993
OPA1	O60313-1.3	I432T	Pathogenic	0.986
OPA1	O60313-1.3	I432V	Pathogenic	0.717
OPA1	O60313-1.3	I432W	Pathogenic	0.999
OPA1	O60313-1.3	I432Y	Pathogenic	0.993
OPA1	O60313-1.3	I433A	Pathogenic	0.985
OPA1	O60313-1.3	I433C	Pathogenic	0.993
OPA1	O60313-1.3	I433D	Pathogenic	0.996
OPA1	O60313-1.3	I433E	Pathogenic	0.996
OPA1	O60313-1.3	I433F	Pathogenic	0.991
OPA1	O60313-1.3	I433G	Pathogenic	0.999
OPA1	O60313-1.3	I433H	Pathogenic	0.998
OPA1	O60313-1.3	I433K	Pathogenic	0.995
OPA1	O60313-1.3	I433L	Pathogenic	0.925
OPA1	O60313-1.3	I433M	Pathogenic	0.959
OPA1	O60313-1.3	I433N	Pathogenic	0.996
OPA1	O60313-1.3	I433P	Pathogenic	0.999
OPA1	O60313-1.3	I433Q	Pathogenic	0.998
OPA1	O60313-1.3	I433R	Pathogenic	0.995
OPA1	O60313-1.3	I433S	Pathogenic	0.993
OPA1	O60313-1.3	I433T	Pathogenic	0.986
OPA1	O60313-1.3	I433V	Pathogenic	0.717
OPA1	O60313-1.3	I433W	Pathogenic	0.999
OPA1	O60313-1.3	I433Y	Pathogenic	0.993
OPA1	O60313-1.3	L434A	Pathogenic	0.982
OPA1	O60313-1.3	L434C	Pathogenic	0.991
OPA1	O60313-1.3	L434D	Pathogenic	0.998
OPA1	O60313-1.3	L434E	Pathogenic	0.996
OPA1	O60313-1.3	L434F	Pathogenic	0.987
OPA1	O60313-1.3	L434G	Pathogenic	0.999
OPA1	O60313-1.3	L434H	Pathogenic	0.998
OPA1	O60313-1.3	L434I	Pathogenic	0.902
OPA1	O60313-1.3	L434K	Pathogenic	0.983
OPA1	O60313-1.3	L434M	Pathogenic	0.868
OPA1	O60313-1.3	L434N	Pathogenic	0.996
OPA1	O60313-1.3	L434P	Pathogenic	0.999
OPA1	O60313-1.3	L434Q	Pathogenic	0.992
OPA1	O60313-1.3	L434R	Pathogenic	0.982
OPA1	O60313-1.3	L434S	Pathogenic	0.992
OPA1	O60313-1.3	L434T	Pathogenic	0.983
OPA1	O60313-1.3	L434V	Pathogenic	0.946
OPA1	O60313-1.3	L434W	Pathogenic	0.997
OPA1	O60313-1.3	L434Y	Pathogenic	0.992
OPA1	O60313-1.3	C435A	Pathogenic	0.991
OPA1	O60313-1.3	C435D	Pathogenic	0.999
OPA1	O60313-1.3	C435E	Pathogenic	1.0
OPA1	O60313-1.3	C435F	Pathogenic	0.999
OPA1	O60313-1.3	C435G	Pathogenic	0.999
OPA1	O60313-1.3	C435H	Pathogenic	1.0
OPA1	O60313-1.3	C435I	Pathogenic	0.996
OPA1	O60313-1.3	C435K	Pathogenic	0.999
OPA1	O60313-1.3	C435L	Pathogenic	0.997
OPA1	O60313-1.3	C435M	Pathogenic	0.998
OPA1	O60313-1.3	C435N	Pathogenic	0.999
OPA1	O60313-1.3	C435P	Pathogenic	1.0
OPA1	O60313-1.3	C435Q	Pathogenic	0.999
OPA1	O60313-1.3	C435R	Pathogenic	0.999
OPA1	O60313-1.3	C435S	Pathogenic	0.996
OPA1	O60313-1.3	C435T	Pathogenic	0.997
OPA1	O60313-1.3	C435V	Pathogenic	0.998
OPA1	O60313-1.3	C435W	Pathogenic	0.998
OPA1	O60313-1.3	C435Y	Pathogenic	0.999
OPA1	O60313-1.3	I436A	Pathogenic	0.985
OPA1	O60313-1.3	I436C	Pathogenic	0.993
OPA1	O60313-1.3	I436D	Pathogenic	0.996
OPA1	O60313-1.3	I436E	Pathogenic	0.996
OPA1	O60313-1.3	I436F	Pathogenic	0.991
OPA1	O60313-1.3	I436G	Pathogenic	0.999
OPA1	O60313-1.3	I436H	Pathogenic	0.998
OPA1	O60313-1.3	I436K	Pathogenic	0.995
OPA1	O60313-1.3	I436L	Pathogenic	0.925
OPA1	O60313-1.3	I436M	Pathogenic	0.959
OPA1	O60313-1.3	I436N	Pathogenic	0.996
OPA1	O60313-1.3	I436P	Pathogenic	0.999
OPA1	O60313-1.3	I436Q	Pathogenic	0.998
OPA1	O60313-1.3	I436R	Pathogenic	0.995
OPA1	O60313-1.3	I436S	Pathogenic	0.993
OPA1	O60313-1.3	I436T	Pathogenic	0.986
OPA1	O60313-1.3	I436V	Pathogenic	0.717
OPA1	O60313-1.3	I436W	Pathogenic	0.999
OPA1	O60313-1.3	I436Y	Pathogenic	0.993
OPA1	O60313-1.3	Q437A	Pathogenic	0.994
OPA1	O60313-1.3	Q437C	Pathogenic	0.999
OPA1	O60313-1.3	Q437D	Pathogenic	0.984
OPA1	O60313-1.3	Q437E	Pathogenic	0.9
OPA1	O60313-1.3	Q437F	Pathogenic	0.998
OPA1	O60313-1.3	Q437G	Pathogenic	0.998
OPA1	O60313-1.3	Q437H	Pathogenic	0.988
OPA1	O60313-1.3	Q437I	Pathogenic	0.998
OPA1	O60313-1.3	Q437K	Pathogenic	0.947
OPA1	O60313-1.3	Q437L	Pathogenic	0.994
OPA1	O60313-1.3	Q437M	Pathogenic	0.967
OPA1	O60313-1.3	Q437N	Pathogenic	0.987
OPA1	O60313-1.3	Q437P	Pathogenic	0.992
OPA1	O60313-1.3	Q437R	Pathogenic	0.944
OPA1	O60313-1.3	Q437S	Pathogenic	0.988
OPA1	O60313-1.3	Q437T	Pathogenic	0.995
OPA1	O60313-1.3	Q437V	Pathogenic	0.996
OPA1	O60313-1.3	Q437W	Pathogenic	0.988
OPA1	O60313-1.3	Q437Y	Pathogenic	0.99
OPA1	O60313-1.3	D438A	Pathogenic	0.997
OPA1	O60313-1.3	D438C	Pathogenic	0.998
OPA1	O60313-1.3	D438E	Pathogenic	0.914
OPA1	O60313-1.3	D438F	Pathogenic	0.995
OPA1	O60313-1.3	D438G	Pathogenic	0.992
OPA1	O60313-1.3	D438H	Pathogenic	0.992
OPA1	O60313-1.3	D438I	Pathogenic	0.995
OPA1	O60313-1.3	D438K	Pathogenic	0.995
OPA1	O60313-1.3	D438L	Pathogenic	0.999
OPA1	O60313-1.3	D438M	Pathogenic	0.997
OPA1	O60313-1.3	D438N	Pathogenic	0.969
OPA1	O60313-1.3	D438P	Pathogenic	0.988
OPA1	O60313-1.3	D438Q	Pathogenic	0.983
OPA1	O60313-1.3	D438R	Pathogenic	0.998
OPA1	O60313-1.3	D438S	Pathogenic	0.981
OPA1	O60313-1.3	D438T	Pathogenic	0.992
OPA1	O60313-1.3	D438V	Pathogenic	0.998
OPA1	O60313-1.3	D438W	Pathogenic	0.997
OPA1	O60313-1.3	D438Y	Pathogenic	0.998
OPA1	O60313-1.3	G439A	Pathogenic	0.989
OPA1	O60313-1.3	G439C	Pathogenic	0.999
OPA1	O60313-1.3	G439D	Pathogenic	0.994
OPA1	O60313-1.3	G439E	Pathogenic	0.998
OPA1	O60313-1.3	G439F	Pathogenic	0.998
OPA1	O60313-1.3	G439H	Pathogenic	0.999
OPA1	O60313-1.3	G439I	Pathogenic	0.999
OPA1	O60313-1.3	G439K	Pathogenic	0.997
OPA1	O60313-1.3	G439L	Pathogenic	0.999
OPA1	O60313-1.3	G439M	Pathogenic	0.999
OPA1	O60313-1.3	G439N	Pathogenic	0.984
OPA1	O60313-1.3	G439P	Pathogenic	0.998
OPA1	O60313-1.3	G439Q	Pathogenic	0.999
OPA1	O60313-1.3	G439R	Pathogenic	0.997
OPA1	O60313-1.3	G439S	Pathogenic	0.991
OPA1	O60313-1.3	G439T	Pathogenic	0.999
OPA1	O60313-1.3	G439V	Pathogenic	0.999
OPA1	O60313-1.3	G439W	Pathogenic	0.989
OPA1	O60313-1.3	G439Y	Pathogenic	0.999
OPA1	O60313-1.3	S440A	Pathogenic	0.962
OPA1	O60313-1.3	S440C	Pathogenic	0.991
OPA1	O60313-1.3	S440D	Pathogenic	0.98
OPA1	O60313-1.3	S440E	Pathogenic	0.981
OPA1	O60313-1.3	S440F	Pathogenic	0.992
OPA1	O60313-1.3	S440G	Pathogenic	0.989
OPA1	O60313-1.3	S440H	Pathogenic	0.995
OPA1	O60313-1.3	S440I	Pathogenic	0.993
OPA1	O60313-1.3	S440K	Pathogenic	0.972
OPA1	O60313-1.3	S440L	Pathogenic	0.993
OPA1	O60313-1.3	S440M	Pathogenic	0.987
OPA1	O60313-1.3	S440N	Pathogenic	0.951
OPA1	O60313-1.3	S440P	Pathogenic	0.993
OPA1	O60313-1.3	S440Q	Pathogenic	0.987
OPA1	O60313-1.3	S440R	Pathogenic	0.989
OPA1	O60313-1.3	S440T	Pathogenic	0.962
OPA1	O60313-1.3	S440V	Pathogenic	0.996
OPA1	O60313-1.3	S440W	Pathogenic	0.996
OPA1	O60313-1.3	S440Y	Pathogenic	0.996
OPA1	O60313-1.3	V441A	Pathogenic	0.975
OPA1	O60313-1.3	V441C	Pathogenic	0.996
OPA1	O60313-1.3	V441D	Pathogenic	0.997
OPA1	O60313-1.3	V441E	Pathogenic	0.994
OPA1	O60313-1.3	V441F	Pathogenic	0.994
OPA1	O60313-1.3	V441G	Pathogenic	0.999
OPA1	O60313-1.3	V441H	Pathogenic	0.999
OPA1	O60313-1.3	V441I	Pathogenic	0.7
OPA1	O60313-1.3	V441K	Pathogenic	0.99
OPA1	O60313-1.3	V441L	Pathogenic	0.956
OPA1	O60313-1.3	V441M	Pathogenic	0.971
OPA1	O60313-1.3	V441N	Pathogenic	0.998
OPA1	O60313-1.3	V441P	Pathogenic	0.998
OPA1	O60313-1.3	V441Q	Pathogenic	0.996
OPA1	O60313-1.3	V441R	Pathogenic	0.996
OPA1	O60313-1.3	V441S	Pathogenic	0.996
OPA1	O60313-1.3	V441T	Pathogenic	0.976
OPA1	O60313-1.3	V441W	Pathogenic	0.999
OPA1	O60313-1.3	V441Y	Pathogenic	0.995
OPA1	O60313-1.3	D442A	Pathogenic	0.997
OPA1	O60313-1.3	D442C	Pathogenic	0.998
OPA1	O60313-1.3	D442E	Pathogenic	0.914
OPA1	O60313-1.3	D442F	Pathogenic	0.995
OPA1	O60313-1.3	D442G	Pathogenic	0.992
OPA1	O60313-1.3	D442H	Pathogenic	0.992
OPA1	O60313-1.3	D442I	Pathogenic	0.995
OPA1	O60313-1.3	D442K	Pathogenic	0.995
OPA1	O60313-1.3	D442L	Pathogenic	0.999
OPA1	O60313-1.3	D442M	Pathogenic	0.997
OPA1	O60313-1.3	D442N	Pathogenic	0.969
OPA1	O60313-1.3	D442P	Pathogenic	0.988
OPA1	O60313-1.3	D442Q	Pathogenic	0.983
OPA1	O60313-1.3	D442R	Pathogenic	0.998
OPA1	O60313-1.3	D442S	Pathogenic	0.981
OPA1	O60313-1.3	D442T	Pathogenic	0.992
OPA1	O60313-1.3	D442V	Pathogenic	0.998
OPA1	O60313-1.3	D442W	Pathogenic	0.997
OPA1	O60313-1.3	D442Y	Pathogenic	0.998
OPA1	O60313-1.3	A443C	Pathogenic	0.982
OPA1	O60313-1.3	A443D	Pathogenic	0.997
OPA1	O60313-1.3	A443E	Pathogenic	0.991
OPA1	O60313-1.3	A443F	Pathogenic	0.995
OPA1	O60313-1.3	A443G	Pathogenic	0.987
OPA1	O60313-1.3	A443H	Pathogenic	0.998
OPA1	O60313-1.3	A443I	Pathogenic	0.985
OPA1	O60313-1.3	A443K	Pathogenic	0.987
OPA1	O60313-1.3	A443L	Pathogenic	0.986
OPA1	O60313-1.3	A443M	Pathogenic	0.991
OPA1	O60313-1.3	A443N	Pathogenic	0.997
OPA1	O60313-1.3	A443P	Pathogenic	0.995
OPA1	O60313-1.3	A443Q	Pathogenic	0.994
OPA1	O60313-1.3	A443R	Pathogenic	0.986
OPA1	O60313-1.3	A443S	Pathogenic	0.964
OPA1	O60313-1.3	A443T	Pathogenic	0.99
OPA1	O60313-1.3	A443V	Pathogenic	0.976
OPA1	O60313-1.3	A443W	Pathogenic	0.997
OPA1	O60313-1.3	A443Y	Pathogenic	0.997
OPA1	O60313-1.3	E444A	Pathogenic	0.99
OPA1	O60313-1.3	E444C	Pathogenic	0.999
OPA1	O60313-1.3	E444D	Pathogenic	0.9
OPA1	O60313-1.3	E444F	Pathogenic	0.995
OPA1	O60313-1.3	E444G	Pathogenic	0.997
OPA1	O60313-1.3	E444H	Pathogenic	0.978
OPA1	O60313-1.3	E444I	Pathogenic	0.996
OPA1	O60313-1.3	E444K	Pathogenic	0.954
OPA1	O60313-1.3	E444L	Pathogenic	0.996
OPA1	O60313-1.3	E444M	Pathogenic	0.992
OPA1	O60313-1.3	E444N	Pathogenic	0.988
OPA1	O60313-1.3	E444P	Pathogenic	0.986
OPA1	O60313-1.3	E444Q	Pathogenic	0.88
OPA1	O60313-1.3	E444R	Pathogenic	0.983
OPA1	O60313-1.3	E444S	Pathogenic	0.979
OPA1	O60313-1.3	E444T	Pathogenic	0.991
OPA1	O60313-1.3	E444V	Pathogenic	0.993
OPA1	O60313-1.3	E444W	Pathogenic	0.992
OPA1	O60313-1.3	E444Y	Pathogenic	0.994
OPA1	O60313-1.3	R445A	Pathogenic	0.983
OPA1	O60313-1.3	R445C	Pathogenic	0.996
OPA1	O60313-1.3	R445D	Pathogenic	0.998
OPA1	O60313-1.3	R445E	Pathogenic	0.982
OPA1	O60313-1.3	R445F	Pathogenic	0.994
OPA1	O60313-1.3	R445G	Pathogenic	0.995
OPA1	O60313-1.3	R445H	Pathogenic	0.965
OPA1	O60313-1.3	R445I	Pathogenic	0.993
OPA1	O60313-1.3	R445K	Pathogenic	0.907
OPA1	O60313-1.3	R445L	Pathogenic	0.983
OPA1	O60313-1.3	R445M	Pathogenic	0.968
OPA1	O60313-1.3	R445N	Pathogenic	0.98
OPA1	O60313-1.3	R445P	Pathogenic	0.992
OPA1	O60313-1.3	R445Q	Pathogenic	0.928
OPA1	O60313-1.3	R445S	Pathogenic	0.988
OPA1	O60313-1.3	R445T	Pathogenic	0.985
OPA1	O60313-1.3	R445V	Pathogenic	0.996
OPA1	O60313-1.3	R445W	Pathogenic	0.99
OPA1	O60313-1.3	R445Y	Pathogenic	0.992
OPA1	O60313-1.3	S446A	Pathogenic	0.955
OPA1	O60313-1.3	S446C	Pathogenic	0.99
OPA1	O60313-1.3	S446D	Pathogenic	0.977
OPA1	O60313-1.3	S446E	Pathogenic	0.978
OPA1	O60313-1.3	S446F	Pathogenic	0.991
OPA1	O60313-1.3	S446G	Pathogenic	0.987
OPA1	O60313-1.3	S446H	Pathogenic	0.995
OPA1	O60313-1.3	S446I	Pathogenic	0.991
OPA1	O60313-1.3	S446K	Pathogenic	0.966
OPA1	O60313-1.3	S446L	Pathogenic	0.992
OPA1	O60313-1.3	S446M	Pathogenic	0.985
OPA1	O60313-1.3	S446N	Pathogenic	0.943
OPA1	O60313-1.3	S446P	Pathogenic	0.992
OPA1	O60313-1.3	S446Q	Pathogenic	0.984
OPA1	O60313-1.3	S446R	Pathogenic	0.987
OPA1	O60313-1.3	S446T	Pathogenic	0.955
OPA1	O60313-1.3	S446V	Pathogenic	0.995
OPA1	O60313-1.3	S446W	Pathogenic	0.995
OPA1	O60313-1.3	S446Y	Pathogenic	0.996
OPA1	O60313-1.3	I447A	Pathogenic	0.711
OPA1	O60313-1.3	I447C	Pathogenic	0.831
OPA1	O60313-1.3	I447D	Pathogenic	0.894
OPA1	O60313-1.3	I447E	Pathogenic	0.911
OPA1	O60313-1.3	I447F	Pathogenic	0.797
OPA1	O60313-1.3	I447G	Pathogenic	0.977
OPA1	O60313-1.3	I447H	Pathogenic	0.955
OPA1	O60313-1.3	I447K	Pathogenic	0.882
OPA1	O60313-1.3	I447L	Neutral	0.309
OPA1	O60313-1.3	I447M	Neutral	0.458
OPA1	O60313-1.3	I447N	Pathogenic	0.909
OPA1	O60313-1.3	I447P	Pathogenic	0.97
OPA1	O60313-1.3	I447Q	Pathogenic	0.938
OPA1	O60313-1.3	I447R	Pathogenic	0.876
OPA1	O60313-1.3	I447S	Pathogenic	0.842
OPA1	O60313-1.3	I447T	Pathogenic	0.722
OPA1	O60313-1.3	I447V	Neutral	0.085
OPA1	O60313-1.3	I447W	Pathogenic	0.983
OPA1	O60313-1.3	I447Y	Pathogenic	0.839
OPA1	O60313-1.3	V448A	Pathogenic	0.947
OPA1	O60313-1.3	V448C	Pathogenic	0.99
OPA1	O60313-1.3	V448D	Pathogenic	0.994
OPA1	O60313-1.3	V448E	Pathogenic	0.986
OPA1	O60313-1.3	V448F	Pathogenic	0.986
OPA1	O60313-1.3	V448G	Pathogenic	0.997
OPA1	O60313-1.3	V448H	Pathogenic	0.998
OPA1	O60313-1.3	V448I	Pathogenic	0.513
OPA1	O60313-1.3	V448K	Pathogenic	0.979
OPA1	O60313-1.3	V448L	Pathogenic	0.907
OPA1	O60313-1.3	V448M	Pathogenic	0.937
OPA1	O60313-1.3	V448N	Pathogenic	0.995
OPA1	O60313-1.3	V448P	Pathogenic	0.996
OPA1	O60313-1.3	V448Q	Pathogenic	0.99
OPA1	O60313-1.3	V448R	Pathogenic	0.992
OPA1	O60313-1.3	V448S	Pathogenic	0.991
OPA1	O60313-1.3	V448T	Pathogenic	0.949
OPA1	O60313-1.3	V448W	Pathogenic	0.997
OPA1	O60313-1.3	V448Y	Pathogenic	0.99
OPA1	O60313-1.3	T449A	Pathogenic	0.978
OPA1	O60313-1.3	T449C	Pathogenic	0.987
OPA1	O60313-1.3	T449D	Pathogenic	0.983
OPA1	O60313-1.3	T449E	Pathogenic	0.984
OPA1	O60313-1.3	T449F	Pathogenic	0.989
OPA1	O60313-1.3	T449G	Pathogenic	0.997
OPA1	O60313-1.3	T449H	Pathogenic	0.997
OPA1	O60313-1.3	T449I	Pathogenic	0.97
OPA1	O60313-1.3	T449K	Pathogenic	0.976
OPA1	O60313-1.3	T449L	Pathogenic	0.972
OPA1	O60313-1.3	T449M	Pathogenic	0.982
OPA1	O60313-1.3	T449N	Pathogenic	0.958
OPA1	O60313-1.3	T449P	Pathogenic	0.99
OPA1	O60313-1.3	T449Q	Pathogenic	0.989
OPA1	O60313-1.3	T449R	Pathogenic	0.974
OPA1	O60313-1.3	T449S	Pathogenic	0.926
OPA1	O60313-1.3	T449V	Pathogenic	0.953
OPA1	O60313-1.3	T449W	Pathogenic	0.982
OPA1	O60313-1.3	T449Y	Pathogenic	0.995
OPA1	O60313-1.3	D450A	Pathogenic	0.993
OPA1	O60313-1.3	D450C	Pathogenic	0.996
OPA1	O60313-1.3	D450E	Pathogenic	0.827
OPA1	O60313-1.3	D450F	Pathogenic	0.99
OPA1	O60313-1.3	D450G	Pathogenic	0.983
OPA1	O60313-1.3	D450H	Pathogenic	0.982
OPA1	O60313-1.3	D450I	Pathogenic	0.99
OPA1	O60313-1.3	D450K	Pathogenic	0.99
OPA1	O60313-1.3	D450L	Pathogenic	0.997
OPA1	O60313-1.3	D450M	Pathogenic	0.994
OPA1	O60313-1.3	D450N	Pathogenic	0.934
OPA1	O60313-1.3	D450P	Pathogenic	0.973
OPA1	O60313-1.3	D450Q	Pathogenic	0.964
OPA1	O60313-1.3	D450R	Pathogenic	0.996
OPA1	O60313-1.3	D450S	Pathogenic	0.959
OPA1	O60313-1.3	D450T	Pathogenic	0.982
OPA1	O60313-1.3	D450V	Pathogenic	0.995
OPA1	O60313-1.3	D450W	Pathogenic	0.994
OPA1	O60313-1.3	D450Y	Pathogenic	0.995
OPA1	O60313-1.3	L451A	Pathogenic	0.979
OPA1	O60313-1.3	L451C	Pathogenic	0.989
OPA1	O60313-1.3	L451D	Pathogenic	0.998
OPA1	O60313-1.3	L451E	Pathogenic	0.995
OPA1	O60313-1.3	L451F	Pathogenic	0.985
OPA1	O60313-1.3	L451G	Pathogenic	0.999
OPA1	O60313-1.3	L451H	Pathogenic	0.998
OPA1	O60313-1.3	L451I	Pathogenic	0.886
OPA1	O60313-1.3	L451K	Pathogenic	0.98
OPA1	O60313-1.3	L451M	Pathogenic	0.848
OPA1	O60313-1.3	L451N	Pathogenic	0.995
OPA1	O60313-1.3	L451P	Pathogenic	0.998
OPA1	O60313-1.3	L451Q	Pathogenic	0.99
OPA1	O60313-1.3	L451R	Pathogenic	0.979
OPA1	O60313-1.3	L451S	Pathogenic	0.99
OPA1	O60313-1.3	L451T	Pathogenic	0.98
OPA1	O60313-1.3	L451V	Pathogenic	0.937
OPA1	O60313-1.3	L451W	Pathogenic	0.997
OPA1	O60313-1.3	L451Y	Pathogenic	0.99
OPA1	O60313-1.3	V452A	Pathogenic	0.947
OPA1	O60313-1.3	V452C	Pathogenic	0.99
OPA1	O60313-1.3	V452D	Pathogenic	0.994
OPA1	O60313-1.3	V452E	Pathogenic	0.986
OPA1	O60313-1.3	V452F	Pathogenic	0.986
OPA1	O60313-1.3	V452G	Pathogenic	0.997
OPA1	O60313-1.3	V452H	Pathogenic	0.998
OPA1	O60313-1.3	V452I	Pathogenic	0.513
OPA1	O60313-1.3	V452K	Pathogenic	0.979
OPA1	O60313-1.3	V452L	Pathogenic	0.907
OPA1	O60313-1.3	V452M	Pathogenic	0.937
OPA1	O60313-1.3	V452N	Pathogenic	0.995
OPA1	O60313-1.3	V452P	Pathogenic	0.996
OPA1	O60313-1.3	V452Q	Pathogenic	0.99
OPA1	O60313-1.3	V452R	Pathogenic	0.992
OPA1	O60313-1.3	V452S	Pathogenic	0.991
OPA1	O60313-1.3	V452T	Pathogenic	0.949
OPA1	O60313-1.3	V452W	Pathogenic	0.997
OPA1	O60313-1.3	V452Y	Pathogenic	0.99
OPA1	O60313-1.3	S453A	Neutral	0.478
OPA1	O60313-1.3	S453C	Pathogenic	0.802
OPA1	O60313-1.3	S453D	Pathogenic	0.64
OPA1	O60313-1.3	S453E	Pathogenic	0.653
OPA1	O60313-1.3	S453F	Pathogenic	0.824
OPA1	O60313-1.3	S453G	Pathogenic	0.766
OPA1	O60313-1.3	S453H	Pathogenic	0.887
OPA1	O60313-1.3	S453I	Pathogenic	0.828
OPA1	O60313-1.3	S453K	Pathogenic	0.553
OPA1	O60313-1.3	S453L	Pathogenic	0.841
OPA1	O60313-1.3	S453M	Pathogenic	0.737
OPA1	O60313-1.3	S453N	Neutral	0.413
OPA1	O60313-1.3	S453P	Pathogenic	0.835
OPA1	O60313-1.3	S453Q	Pathogenic	0.73
OPA1	O60313-1.3	S453R	Pathogenic	0.771
OPA1	O60313-1.3	S453T	Neutral	0.477
OPA1	O60313-1.3	S453V	Pathogenic	0.898
OPA1	O60313-1.3	S453W	Pathogenic	0.889
OPA1	O60313-1.3	S453Y	Pathogenic	0.907
OPA1	O60313-1.3	Q454A	Pathogenic	0.981
OPA1	O60313-1.3	Q454C	Pathogenic	0.996
OPA1	O60313-1.3	Q454D	Pathogenic	0.949
OPA1	O60313-1.3	Q454E	Pathogenic	0.73
OPA1	O60313-1.3	Q454F	Pathogenic	0.992
OPA1	O60313-1.3	Q454G	Pathogenic	0.995
OPA1	O60313-1.3	Q454H	Pathogenic	0.96
OPA1	O60313-1.3	Q454I	Pathogenic	0.992
OPA1	O60313-1.3	Q454K	Pathogenic	0.842
OPA1	O60313-1.3	Q454L	Pathogenic	0.979
OPA1	O60313-1.3	Q454M	Pathogenic	0.896
OPA1	O60313-1.3	Q454N	Pathogenic	0.957
OPA1	O60313-1.3	Q454P	Pathogenic	0.974
OPA1	O60313-1.3	Q454R	Pathogenic	0.834
OPA1	O60313-1.3	Q454S	Pathogenic	0.961
OPA1	O60313-1.3	Q454T	Pathogenic	0.983
OPA1	O60313-1.3	Q454V	Pathogenic	0.987
OPA1	O60313-1.3	Q454W	Pathogenic	0.961
OPA1	O60313-1.3	Q454Y	Pathogenic	0.968
OPA1	O60313-1.3	M455A	Pathogenic	0.936
OPA1	O60313-1.3	M455C	Pathogenic	0.967
OPA1	O60313-1.3	M455D	Pathogenic	0.98
OPA1	O60313-1.3	M455E	Pathogenic	0.954
OPA1	O60313-1.3	M455F	Pathogenic	0.893
OPA1	O60313-1.3	M455G	Pathogenic	0.989
OPA1	O60313-1.3	M455H	Pathogenic	0.978
OPA1	O60313-1.3	M455I	Pathogenic	0.747
OPA1	O60313-1.3	M455K	Pathogenic	0.841
OPA1	O60313-1.3	M455L	Pathogenic	0.529
OPA1	O60313-1.3	M455N	Pathogenic	0.953
OPA1	O60313-1.3	M455P	Pathogenic	0.985
OPA1	O60313-1.3	M455Q	Pathogenic	0.787
OPA1	O60313-1.3	M455R	Pathogenic	0.832
OPA1	O60313-1.3	M455S	Pathogenic	0.916
OPA1	O60313-1.3	M455T	Pathogenic	0.939
OPA1	O60313-1.3	M455V	Pathogenic	0.821
OPA1	O60313-1.3	M455W	Pathogenic	0.935
OPA1	O60313-1.3	M455Y	Pathogenic	0.969
OPA1	O60313-1.3	D456A	Pathogenic	0.993
OPA1	O60313-1.3	D456C	Pathogenic	0.996
OPA1	O60313-1.3	D456E	Pathogenic	0.837
OPA1	O60313-1.3	D456F	Pathogenic	0.99
OPA1	O60313-1.3	D456G	Pathogenic	0.985
OPA1	O60313-1.3	D456H	Pathogenic	0.984
OPA1	O60313-1.3	D456I	Pathogenic	0.991
OPA1	O60313-1.3	D456K	Pathogenic	0.991
OPA1	O60313-1.3	D456L	Pathogenic	0.997
OPA1	O60313-1.3	D456M	Pathogenic	0.994
OPA1	O60313-1.3	D456N	Pathogenic	0.938
OPA1	O60313-1.3	D456P	Pathogenic	0.975
OPA1	O60313-1.3	D456Q	Pathogenic	0.967
OPA1	O60313-1.3	D456R	Pathogenic	0.997
OPA1	O60313-1.3	D456S	Pathogenic	0.961
OPA1	O60313-1.3	D456T	Pathogenic	0.983
OPA1	O60313-1.3	D456V	Pathogenic	0.995
OPA1	O60313-1.3	D456W	Pathogenic	0.994
OPA1	O60313-1.3	D456Y	Pathogenic	0.995
OPA1	O60313-1.3	P457A	Pathogenic	0.996
OPA1	O60313-1.3	P457C	Pathogenic	1.0
OPA1	O60313-1.3	P457D	Pathogenic	0.99
OPA1	O60313-1.3	P457E	Pathogenic	0.991
OPA1	O60313-1.3	P457F	Pathogenic	1.0
OPA1	O60313-1.3	P457G	Pathogenic	0.998
OPA1	O60313-1.3	P457H	Pathogenic	0.998
OPA1	O60313-1.3	P457I	Pathogenic	0.999
OPA1	O60313-1.3	P457K	Pathogenic	0.986
OPA1	O60313-1.3	P457L	Pathogenic	0.999
OPA1	O60313-1.3	P457M	Pathogenic	0.998
OPA1	O60313-1.3	P457N	Pathogenic	0.997
OPA1	O60313-1.3	P457Q	Pathogenic	0.994
OPA1	O60313-1.3	P457R	Pathogenic	0.995
OPA1	O60313-1.3	P457S	Pathogenic	0.995
OPA1	O60313-1.3	P457T	Pathogenic	0.996
OPA1	O60313-1.3	P457V	Pathogenic	0.999
OPA1	O60313-1.3	P457W	Pathogenic	0.999
OPA1	O60313-1.3	P457Y	Pathogenic	1.0
OPA1	O60313-1.3	H458A	Neutral	0.399
OPA1	O60313-1.3	H458C	Pathogenic	0.527
OPA1	O60313-1.3	H458D	Neutral	0.114
OPA1	O60313-1.3	H458E	Neutral	0.051
OPA1	O60313-1.3	H458F	Neutral	0.063
OPA1	O60313-1.3	H458G	Neutral	0.392
OPA1	O60313-1.3	H458I	Neutral	0.367
OPA1	O60313-1.3	H458K	Neutral	0.099
OPA1	O60313-1.3	H458L	Neutral	0.389
OPA1	O60313-1.3	H458M	Neutral	0.252
OPA1	O60313-1.3	H458N	Neutral	0.018
OPA1	O60313-1.3	H458P	Neutral	0.332
OPA1	O60313-1.3	H458Q	Neutral	0.074
OPA1	O60313-1.3	H458R	Neutral	0.034
OPA1	O60313-1.3	H458S	Neutral	0.191
OPA1	O60313-1.3	H458T	Neutral	0.434
OPA1	O60313-1.3	H458V	Neutral	0.491
OPA1	O60313-1.3	H458W	Neutral	0.103
OPA1	O60313-1.3	H458Y	Neutral	0.006
OPA1	O60313-1.3	G459A	Pathogenic	0.97
OPA1	O60313-1.3	G459C	Pathogenic	0.997
OPA1	O60313-1.3	G459D	Pathogenic	0.982
OPA1	O60313-1.3	G459E	Pathogenic	0.994
OPA1	O60313-1.3	G459F	Pathogenic	0.994
OPA1	O60313-1.3	G459H	Pathogenic	0.996
OPA1	O60313-1.3	G459I	Pathogenic	0.998
OPA1	O60313-1.3	G459K	Pathogenic	0.991
OPA1	O60313-1.3	G459L	Pathogenic	0.998
OPA1	O60313-1.3	G459M	Pathogenic	0.996
OPA1	O60313-1.3	G459N	Pathogenic	0.957
OPA1	O60313-1.3	G459P	Pathogenic	0.994
OPA1	O60313-1.3	G459Q	Pathogenic	0.996
OPA1	O60313-1.3	G459R	Pathogenic	0.991
OPA1	O60313-1.3	G459S	Pathogenic	0.976
OPA1	O60313-1.3	G459T	Pathogenic	0.996
OPA1	O60313-1.3	G459V	Pathogenic	0.997
OPA1	O60313-1.3	G459W	Pathogenic	0.97
OPA1	O60313-1.3	G459Y	Pathogenic	0.997
OPA1	O60313-1.3	R460A	Neutral	0.374
OPA1	O60313-1.3	R460C	Pathogenic	0.744
OPA1	O60313-1.3	R460D	Pathogenic	0.836
OPA1	O60313-1.3	R460E	Neutral	0.364
OPA1	O60313-1.3	R460F	Pathogenic	0.625
OPA1	O60313-1.3	R460G	Pathogenic	0.681
OPA1	O60313-1.3	R460H	Neutral	0.227
OPA1	O60313-1.3	R460I	Pathogenic	0.612
OPA1	O60313-1.3	R460K	Neutral	0.094
OPA1	O60313-1.3	R460L	Neutral	0.375
OPA1	O60313-1.3	R460M	Neutral	0.241
OPA1	O60313-1.3	R460N	Neutral	0.345
OPA1	O60313-1.3	R460P	Pathogenic	0.564
OPA1	O60313-1.3	R460Q	Neutral	0.121
OPA1	O60313-1.3	R460S	Neutral	0.456
OPA1	O60313-1.3	R460T	Neutral	0.408
OPA1	O60313-1.3	R460V	Pathogenic	0.716
OPA1	O60313-1.3	R460W	Pathogenic	0.52
OPA1	O60313-1.3	R460Y	Pathogenic	0.557
OPA1	O60313-1.3	R461A	Pathogenic	0.973
OPA1	O60313-1.3	R461C	Pathogenic	0.994
OPA1	O60313-1.3	R461D	Pathogenic	0.997
OPA1	O60313-1.3	R461E	Pathogenic	0.972
OPA1	O60313-1.3	R461F	Pathogenic	0.99
OPA1	O60313-1.3	R461G	Pathogenic	0.992
OPA1	O60313-1.3	R461H	Pathogenic	0.946
OPA1	O60313-1.3	R461I	Pathogenic	0.99
OPA1	O60313-1.3	R461K	Pathogenic	0.862
OPA1	O60313-1.3	R461L	Pathogenic	0.973
OPA1	O60313-1.3	R461M	Pathogenic	0.95
OPA1	O60313-1.3	R461N	Pathogenic	0.969
OPA1	O60313-1.3	R461P	Pathogenic	0.987
OPA1	O60313-1.3	R461Q	Pathogenic	0.892
OPA1	O60313-1.3	R461S	Pathogenic	0.981
OPA1	O60313-1.3	R461T	Pathogenic	0.976
OPA1	O60313-1.3	R461V	Pathogenic	0.993
OPA1	O60313-1.3	R461W	Pathogenic	0.985
OPA1	O60313-1.3	R461Y	Pathogenic	0.987
OPA1	O60313-1.3	T462A	Pathogenic	0.981
OPA1	O60313-1.3	T462C	Pathogenic	0.989
OPA1	O60313-1.3	T462D	Pathogenic	0.986
OPA1	O60313-1.3	T462E	Pathogenic	0.986
OPA1	O60313-1.3	T462F	Pathogenic	0.991
OPA1	O60313-1.3	T462G	Pathogenic	0.997
OPA1	O60313-1.3	T462H	Pathogenic	0.998
OPA1	O60313-1.3	T462I	Pathogenic	0.974
OPA1	O60313-1.3	T462K	Pathogenic	0.98
OPA1	O60313-1.3	T462L	Pathogenic	0.977
OPA1	O60313-1.3	T462M	Pathogenic	0.985
OPA1	O60313-1.3	T462N	Pathogenic	0.965
OPA1	O60313-1.3	T462P	Pathogenic	0.991
OPA1	O60313-1.3	T462Q	Pathogenic	0.991
OPA1	O60313-1.3	T462R	Pathogenic	0.978
OPA1	O60313-1.3	T462S	Pathogenic	0.937
OPA1	O60313-1.3	T462V	Pathogenic	0.96
OPA1	O60313-1.3	T462W	Pathogenic	0.984
OPA1	O60313-1.3	T462Y	Pathogenic	0.996
OPA1	O60313-1.3	I463A	Pathogenic	0.973
OPA1	O60313-1.3	I463C	Pathogenic	0.986
OPA1	O60313-1.3	I463D	Pathogenic	0.992
OPA1	O60313-1.3	I463E	Pathogenic	0.993
OPA1	O60313-1.3	I463F	Pathogenic	0.983
OPA1	O60313-1.3	I463G	Pathogenic	0.998
OPA1	O60313-1.3	I463H	Pathogenic	0.997
OPA1	O60313-1.3	I463K	Pathogenic	0.991
OPA1	O60313-1.3	I463L	Pathogenic	0.868
OPA1	O60313-1.3	I463M	Pathogenic	0.926
OPA1	O60313-1.3	I463N	Pathogenic	0.993
OPA1	O60313-1.3	I463P	Pathogenic	0.998
OPA1	O60313-1.3	I463Q	Pathogenic	0.996
OPA1	O60313-1.3	I463R	Pathogenic	0.99
OPA1	O60313-1.3	I463S	Pathogenic	0.987
OPA1	O60313-1.3	I463T	Pathogenic	0.974
OPA1	O60313-1.3	I463V	Pathogenic	0.576
OPA1	O60313-1.3	I463W	Pathogenic	0.999
OPA1	O60313-1.3	I463Y	Pathogenic	0.987
OPA1	O60313-1.3	F464A	Pathogenic	0.995
OPA1	O60313-1.3	F464C	Pathogenic	0.997
OPA1	O60313-1.3	F464D	Pathogenic	0.996
OPA1	O60313-1.3	F464E	Pathogenic	0.996
OPA1	O60313-1.3	F464G	Pathogenic	0.998
OPA1	O60313-1.3	F464H	Pathogenic	0.986
OPA1	O60313-1.3	F464I	Pathogenic	0.991
OPA1	O60313-1.3	F464K	Pathogenic	0.996
OPA1	O60313-1.3	F464L	Pathogenic	0.99
OPA1	O60313-1.3	F464M	Pathogenic	0.985
OPA1	O60313-1.3	F464N	Pathogenic	0.996
OPA1	O60313-1.3	F464P	Pathogenic	1.0
OPA1	O60313-1.3	F464Q	Pathogenic	0.998
OPA1	O60313-1.3	F464R	Pathogenic	0.995
OPA1	O60313-1.3	F464S	Pathogenic	0.993
OPA1	O60313-1.3	F464T	Pathogenic	0.995
OPA1	O60313-1.3	F464V	Pathogenic	0.994
OPA1	O60313-1.3	F464W	Pathogenic	0.96
OPA1	O60313-1.3	F464Y	Pathogenic	0.688
OPA1	O60313-1.3	V465A	Pathogenic	0.951
OPA1	O60313-1.3	V465C	Pathogenic	0.991
OPA1	O60313-1.3	V465D	Pathogenic	0.995
OPA1	O60313-1.3	V465E	Pathogenic	0.987
OPA1	O60313-1.3	V465F	Pathogenic	0.988
OPA1	O60313-1.3	V465G	Pathogenic	0.997
OPA1	O60313-1.3	V465H	Pathogenic	0.998
OPA1	O60313-1.3	V465I	Pathogenic	0.535
OPA1	O60313-1.3	V465K	Pathogenic	0.981
OPA1	O60313-1.3	V465L	Pathogenic	0.914
OPA1	O60313-1.3	V465M	Pathogenic	0.942
OPA1	O60313-1.3	V465N	Pathogenic	0.996
OPA1	O60313-1.3	V465P	Pathogenic	0.996
OPA1	O60313-1.3	V465Q	Pathogenic	0.991
OPA1	O60313-1.3	V465R	Pathogenic	0.993
OPA1	O60313-1.3	V465S	Pathogenic	0.992
OPA1	O60313-1.3	V465T	Pathogenic	0.953
OPA1	O60313-1.3	V465W	Pathogenic	0.997
OPA1	O60313-1.3	V465Y	Pathogenic	0.99
OPA1	O60313-1.3	L466A	Pathogenic	0.968
OPA1	O60313-1.3	L466C	Pathogenic	0.983
OPA1	O60313-1.3	L466D	Pathogenic	0.997
OPA1	O60313-1.3	L466E	Pathogenic	0.992
OPA1	O60313-1.3	L466F	Pathogenic	0.976
OPA1	O60313-1.3	L466G	Pathogenic	0.998
OPA1	O60313-1.3	L466H	Pathogenic	0.996
OPA1	O60313-1.3	L466I	Pathogenic	0.832
OPA1	O60313-1.3	L466K	Pathogenic	0.969
OPA1	O60313-1.3	L466M	Pathogenic	0.78
OPA1	O60313-1.3	L466N	Pathogenic	0.992
OPA1	O60313-1.3	L466P	Pathogenic	0.998
OPA1	O60313-1.3	L466Q	Pathogenic	0.985
OPA1	O60313-1.3	L466R	Pathogenic	0.967
OPA1	O60313-1.3	L466S	Pathogenic	0.985
OPA1	O60313-1.3	L466T	Pathogenic	0.969
OPA1	O60313-1.3	L466V	Pathogenic	0.904
OPA1	O60313-1.3	L466W	Pathogenic	0.995
OPA1	O60313-1.3	L466Y	Pathogenic	0.984
OPA1	O60313-1.3	T467A	Pathogenic	0.882
OPA1	O60313-1.3	T467C	Pathogenic	0.926
OPA1	O60313-1.3	T467D	Pathogenic	0.907
OPA1	O60313-1.3	T467E	Pathogenic	0.913
OPA1	O60313-1.3	T467F	Pathogenic	0.939
OPA1	O60313-1.3	T467G	Pathogenic	0.98
OPA1	O60313-1.3	T467H	Pathogenic	0.983
OPA1	O60313-1.3	T467I	Pathogenic	0.844
OPA1	O60313-1.3	T467K	Pathogenic	0.873
OPA1	O60313-1.3	T467L	Pathogenic	0.856
OPA1	O60313-1.3	T467M	Pathogenic	0.902
OPA1	O60313-1.3	T467N	Pathogenic	0.796
OPA1	O60313-1.3	T467P	Pathogenic	0.942
OPA1	O60313-1.3	T467Q	Pathogenic	0.938
OPA1	O60313-1.3	T467R	Pathogenic	0.866
OPA1	O60313-1.3	T467S	Pathogenic	0.68
OPA1	O60313-1.3	T467V	Pathogenic	0.775
OPA1	O60313-1.3	T467W	Pathogenic	0.9
OPA1	O60313-1.3	T467Y	Pathogenic	0.97
OPA1	O60313-1.3	K468A	Pathogenic	0.831
OPA1	O60313-1.3	K468C	Pathogenic	0.96
OPA1	O60313-1.3	K468D	Pathogenic	0.935
OPA1	O60313-1.3	K468E	Pathogenic	0.619
OPA1	O60313-1.3	K468F	Pathogenic	0.932
OPA1	O60313-1.3	K468G	Pathogenic	0.946
OPA1	O60313-1.3	K468H	Pathogenic	0.875
OPA1	O60313-1.3	K468I	Pathogenic	0.928
OPA1	O60313-1.3	K468L	Pathogenic	0.831
OPA1	O60313-1.3	K468M	Pathogenic	0.723
OPA1	O60313-1.3	K468N	Pathogenic	0.812
OPA1	O60313-1.3	K468P	Pathogenic	0.786
OPA1	O60313-1.3	K468Q	Pathogenic	0.53
OPA1	O60313-1.3	K468R	Neutral	0.444
OPA1	O60313-1.3	K468S	Pathogenic	0.703
OPA1	O60313-1.3	K468T	Pathogenic	0.85
OPA1	O60313-1.3	K468V	Pathogenic	0.877
OPA1	O60313-1.3	K468W	Pathogenic	0.89
OPA1	O60313-1.3	K468Y	Pathogenic	0.908
OPA1	O60313-1.3	V469A	Pathogenic	0.751
OPA1	O60313-1.3	V469C	Pathogenic	0.946
OPA1	O60313-1.3	V469D	Pathogenic	0.968
OPA1	O60313-1.3	V469E	Pathogenic	0.924
OPA1	O60313-1.3	V469F	Pathogenic	0.925
OPA1	O60313-1.3	V469G	Pathogenic	0.981
OPA1	O60313-1.3	V469H	Pathogenic	0.986
OPA1	O60313-1.3	V469I	Neutral	0.152
OPA1	O60313-1.3	V469K	Pathogenic	0.889
OPA1	O60313-1.3	V469L	Pathogenic	0.623
OPA1	O60313-1.3	V469M	Pathogenic	0.717
OPA1	O60313-1.3	V469N	Pathogenic	0.973
OPA1	O60313-1.3	V469P	Pathogenic	0.976
OPA1	O60313-1.3	V469Q	Pathogenic	0.946
OPA1	O60313-1.3	V469R	Pathogenic	0.956
OPA1	O60313-1.3	V469S	Pathogenic	0.95
OPA1	O60313-1.3	V469T	Pathogenic	0.76
OPA1	O60313-1.3	V469W	Pathogenic	0.984
OPA1	O60313-1.3	V469Y	Pathogenic	0.941
OPA1	O60313-1.3	D470A	Pathogenic	0.959
OPA1	O60313-1.3	D470C	Pathogenic	0.975
OPA1	O60313-1.3	D470E	Neutral	0.448
OPA1	O60313-1.3	D470F	Pathogenic	0.942
OPA1	O60313-1.3	D470G	Pathogenic	0.909
OPA1	O60313-1.3	D470H	Pathogenic	0.904
OPA1	O60313-1.3	D470I	Pathogenic	0.944
OPA1	O60313-1.3	D470K	Pathogenic	0.943
OPA1	O60313-1.3	D470L	Pathogenic	0.982
OPA1	O60313-1.3	D470M	Pathogenic	0.966
OPA1	O60313-1.3	D470N	Pathogenic	0.705
OPA1	O60313-1.3	D470P	Pathogenic	0.859
OPA1	O60313-1.3	D470Q	Pathogenic	0.82
OPA1	O60313-1.3	D470R	Pathogenic	0.978
OPA1	O60313-1.3	D470S	Pathogenic	0.797
OPA1	O60313-1.3	D470T	Pathogenic	0.902
OPA1	O60313-1.3	D470V	Pathogenic	0.969
OPA1	O60313-1.3	D470W	Pathogenic	0.965
OPA1	O60313-1.3	D470Y	Pathogenic	0.972
OPA1	O60313-1.3	L471A	Pathogenic	0.864
OPA1	O60313-1.3	L471C	Pathogenic	0.927
OPA1	O60313-1.3	L471D	Pathogenic	0.984
OPA1	O60313-1.3	L471E	Pathogenic	0.963
OPA1	O60313-1.3	L471F	Pathogenic	0.896
OPA1	O60313-1.3	L471G	Pathogenic	0.991
OPA1	O60313-1.3	L471H	Pathogenic	0.982
OPA1	O60313-1.3	L471I	Pathogenic	0.513
OPA1	O60313-1.3	L471K	Pathogenic	0.87
OPA1	O60313-1.3	L471M	Neutral	0.429
OPA1	O60313-1.3	L471N	Pathogenic	0.963
OPA1	O60313-1.3	L471P	Pathogenic	0.988
OPA1	O60313-1.3	L471Q	Pathogenic	0.931
OPA1	O60313-1.3	L471R	Pathogenic	0.863
OPA1	O60313-1.3	L471S	Pathogenic	0.932
OPA1	O60313-1.3	L471T	Pathogenic	0.87
OPA1	O60313-1.3	L471V	Pathogenic	0.667
OPA1	O60313-1.3	L471W	Pathogenic	0.977
OPA1	O60313-1.3	L471Y	Pathogenic	0.931
OPA1	O60313-1.3	A472C	Pathogenic	0.967
OPA1	O60313-1.3	A472D	Pathogenic	0.994
OPA1	O60313-1.3	A472E	Pathogenic	0.984
OPA1	O60313-1.3	A472F	Pathogenic	0.99
OPA1	O60313-1.3	A472G	Pathogenic	0.976
OPA1	O60313-1.3	A472H	Pathogenic	0.997
OPA1	O60313-1.3	A472I	Pathogenic	0.972
OPA1	O60313-1.3	A472K	Pathogenic	0.976
OPA1	O60313-1.3	A472L	Pathogenic	0.975
OPA1	O60313-1.3	A472M	Pathogenic	0.983
OPA1	O60313-1.3	A472N	Pathogenic	0.995
OPA1	O60313-1.3	A472P	Pathogenic	0.991
OPA1	O60313-1.3	A472Q	Pathogenic	0.989
OPA1	O60313-1.3	A472R	Pathogenic	0.974
OPA1	O60313-1.3	A472S	Pathogenic	0.935
OPA1	O60313-1.3	A472T	Pathogenic	0.981
OPA1	O60313-1.3	A472V	Pathogenic	0.957
OPA1	O60313-1.3	A472W	Pathogenic	0.994
OPA1	O60313-1.3	A472Y	Pathogenic	0.995
OPA1	O60313-1.3	E473A	Pathogenic	0.98
OPA1	O60313-1.3	E473C	Pathogenic	0.999
OPA1	O60313-1.3	E473D	Pathogenic	0.823
OPA1	O60313-1.3	E473F	Pathogenic	0.991
OPA1	O60313-1.3	E473G	Pathogenic	0.994
OPA1	O60313-1.3	E473H	Pathogenic	0.957
OPA1	O60313-1.3	E473I	Pathogenic	0.991
OPA1	O60313-1.3	E473K	Pathogenic	0.914
OPA1	O60313-1.3	E473L	Pathogenic	0.992
OPA1	O60313-1.3	E473M	Pathogenic	0.985
OPA1	O60313-1.3	E473N	Pathogenic	0.977
OPA1	O60313-1.3	E473P	Pathogenic	0.974
OPA1	O60313-1.3	E473Q	Pathogenic	0.79
OPA1	O60313-1.3	E473R	Pathogenic	0.967
OPA1	O60313-1.3	E473S	Pathogenic	0.96
OPA1	O60313-1.3	E473T	Pathogenic	0.983
OPA1	O60313-1.3	E473V	Pathogenic	0.986
OPA1	O60313-1.3	E473W	Pathogenic	0.985
OPA1	O60313-1.3	E473Y	Pathogenic	0.988
OPA1	O60313-1.3	K474A	Pathogenic	0.671
OPA1	O60313-1.3	K474C	Pathogenic	0.908
OPA1	O60313-1.3	K474D	Pathogenic	0.857
OPA1	O60313-1.3	K474E	Neutral	0.402
OPA1	O60313-1.3	K474F	Pathogenic	0.85
OPA1	O60313-1.3	K474G	Pathogenic	0.879
OPA1	O60313-1.3	K474H	Pathogenic	0.743
OPA1	O60313-1.3	K474I	Pathogenic	0.843
OPA1	O60313-1.3	K474L	Pathogenic	0.671
OPA1	O60313-1.3	K474M	Pathogenic	0.519
OPA1	O60313-1.3	K474N	Pathogenic	0.643
OPA1	O60313-1.3	K474P	Pathogenic	0.604
OPA1	O60313-1.3	K474Q	Neutral	0.319
OPA1	O60313-1.3	K474R	Neutral	0.249
OPA1	O60313-1.3	K474S	Neutral	0.496
OPA1	O60313-1.3	K474T	Pathogenic	0.702
OPA1	O60313-1.3	K474V	Pathogenic	0.747
OPA1	O60313-1.3	K474W	Pathogenic	0.77
OPA1	O60313-1.3	K474Y	Pathogenic	0.804
OPA1	O60313-1.3	N475A	Pathogenic	0.987
OPA1	O60313-1.3	N475C	Pathogenic	0.992
OPA1	O60313-1.3	N475D	Pathogenic	0.873
OPA1	O60313-1.3	N475E	Pathogenic	0.956
OPA1	O60313-1.3	N475F	Pathogenic	0.982
OPA1	O60313-1.3	N475G	Pathogenic	0.92
OPA1	O60313-1.3	N475H	Pathogenic	0.794
OPA1	O60313-1.3	N475I	Pathogenic	0.983
OPA1	O60313-1.3	N475K	Pathogenic	0.935
OPA1	O60313-1.3	N475L	Pathogenic	0.984
OPA1	O60313-1.3	N475M	Pathogenic	0.971
OPA1	O60313-1.3	N475P	Pathogenic	0.983
OPA1	O60313-1.3	N475Q	Pathogenic	0.94
OPA1	O60313-1.3	N475R	Pathogenic	0.931
OPA1	O60313-1.3	N475S	Pathogenic	0.818
OPA1	O60313-1.3	N475T	Pathogenic	0.915
OPA1	O60313-1.3	N475V	Pathogenic	0.991
OPA1	O60313-1.3	N475W	Pathogenic	0.99
OPA1	O60313-1.3	N475Y	Pathogenic	0.976
OPA1	O60313-1.3	V476A	Neutral	0.2
OPA1	O60313-1.3	V476C	Pathogenic	0.591
OPA1	O60313-1.3	V476D	Pathogenic	0.714
OPA1	O60313-1.3	V476E	Pathogenic	0.502
OPA1	O60313-1.3	V476F	Pathogenic	0.505
OPA1	O60313-1.3	V476G	Pathogenic	0.811
OPA1	O60313-1.3	V476H	Pathogenic	0.851
OPA1	O60313-1.3	V476I	Neutral	0.015
OPA1	O60313-1.3	V476K	Neutral	0.398
OPA1	O60313-1.3	V476L	Neutral	0.12
OPA1	O60313-1.3	V476M	Neutral	0.174
OPA1	O60313-1.3	V476N	Pathogenic	0.748
OPA1	O60313-1.3	V476P	Pathogenic	0.77
OPA1	O60313-1.3	V476Q	Pathogenic	0.592
OPA1	O60313-1.3	V476R	Pathogenic	0.643
OPA1	O60313-1.3	V476S	Pathogenic	0.611
OPA1	O60313-1.3	V476T	Neutral	0.209
OPA1	O60313-1.3	V476W	Pathogenic	0.835
OPA1	O60313-1.3	V476Y	Pathogenic	0.571
OPA1	O60313-1.3	A477C	Pathogenic	0.76
OPA1	O60313-1.3	A477D	Pathogenic	0.948
OPA1	O60313-1.3	A477E	Pathogenic	0.868
OPA1	O60313-1.3	A477F	Pathogenic	0.914
OPA1	O60313-1.3	A477G	Pathogenic	0.816
OPA1	O60313-1.3	A477H	Pathogenic	0.974
OPA1	O60313-1.3	A477I	Pathogenic	0.79
OPA1	O60313-1.3	A477K	Pathogenic	0.812
OPA1	O60313-1.3	A477L	Pathogenic	0.805
OPA1	O60313-1.3	A477M	Pathogenic	0.864
OPA1	O60313-1.3	A477N	Pathogenic	0.954
OPA1	O60313-1.3	A477P	Pathogenic	0.92
OPA1	O60313-1.3	A477Q	Pathogenic	0.905
OPA1	O60313-1.3	A477R	Pathogenic	0.803
OPA1	O60313-1.3	A477S	Pathogenic	0.609
OPA1	O60313-1.3	A477T	Pathogenic	0.845
OPA1	O60313-1.3	A477V	Pathogenic	0.705
OPA1	O60313-1.3	A477W	Pathogenic	0.948
OPA1	O60313-1.3	A477Y	Pathogenic	0.957
OPA1	O60313-1.3	S478A	Neutral	0.358
OPA1	O60313-1.3	S478C	Pathogenic	0.711
OPA1	O60313-1.3	S478D	Pathogenic	0.52
OPA1	O60313-1.3	S478E	Pathogenic	0.533
OPA1	O60313-1.3	S478F	Pathogenic	0.739
OPA1	O60313-1.3	S478G	Pathogenic	0.666
OPA1	O60313-1.3	S478H	Pathogenic	0.826
OPA1	O60313-1.3	S478I	Pathogenic	0.745
OPA1	O60313-1.3	S478K	Neutral	0.429
OPA1	O60313-1.3	S478L	Pathogenic	0.762
OPA1	O60313-1.3	S478M	Pathogenic	0.629
OPA1	O60313-1.3	S478N	Neutral	0.299
OPA1	O60313-1.3	S478P	Pathogenic	0.755
OPA1	O60313-1.3	S478Q	Pathogenic	0.621
OPA1	O60313-1.3	S478R	Pathogenic	0.672
OPA1	O60313-1.3	S478T	Neutral	0.356
OPA1	O60313-1.3	S478V	Pathogenic	0.843
OPA1	O60313-1.3	S478W	Pathogenic	0.829
OPA1	O60313-1.3	S478Y	Pathogenic	0.856
OPA1	O60313-1.3	P479A	Pathogenic	0.99
OPA1	O60313-1.3	P479C	Pathogenic	0.999
OPA1	O60313-1.3	P479D	Pathogenic	0.977
OPA1	O60313-1.3	P479E	Pathogenic	0.978
OPA1	O60313-1.3	P479F	Pathogenic	0.999
OPA1	O60313-1.3	P479G	Pathogenic	0.995
OPA1	O60313-1.3	P479H	Pathogenic	0.996
OPA1	O60313-1.3	P479I	Pathogenic	0.998
OPA1	O60313-1.3	P479K	Pathogenic	0.967
OPA1	O60313-1.3	P479L	Pathogenic	0.998
OPA1	O60313-1.3	P479M	Pathogenic	0.996
OPA1	O60313-1.3	P479N	Pathogenic	0.993
OPA1	O60313-1.3	P479Q	Pathogenic	0.984
OPA1	O60313-1.3	P479R	Pathogenic	0.987
OPA1	O60313-1.3	P479S	Pathogenic	0.987
OPA1	O60313-1.3	P479T	Pathogenic	0.991
OPA1	O60313-1.3	P479V	Pathogenic	0.996
OPA1	O60313-1.3	P479W	Pathogenic	0.999
OPA1	O60313-1.3	P479Y	Pathogenic	0.999
OPA1	O60313-1.3	S480A	Neutral	0.024
OPA1	O60313-1.3	S480C	Neutral	0.096
OPA1	O60313-1.3	S480D	Neutral	0.045
OPA1	O60313-1.3	S480E	Neutral	0.047
OPA1	O60313-1.3	S480F	Neutral	0.109
OPA1	O60313-1.3	S480G	Neutral	0.079
OPA1	O60313-1.3	S480H	Neutral	0.171
OPA1	O60313-1.3	S480I	Neutral	0.112
OPA1	O60313-1.3	S480K	Neutral	0.031
OPA1	O60313-1.3	S480L	Neutral	0.122
OPA1	O60313-1.3	S480M	Neutral	0.068
OPA1	O60313-1.3	S480N	Neutral	0.018
OPA1	O60313-1.3	S480P	Neutral	0.118
OPA1	O60313-1.3	S480Q	Neutral	0.066
OPA1	O60313-1.3	S480R	Neutral	0.081
OPA1	O60313-1.3	S480T	Neutral	0.023
OPA1	O60313-1.3	S480V	Neutral	0.188
OPA1	O60313-1.3	S480W	Neutral	0.174
OPA1	O60313-1.3	S480Y	Neutral	0.204
OPA1	O60313-1.3	R481A	Pathogenic	0.94
OPA1	O60313-1.3	R481C	Pathogenic	0.987
OPA1	O60313-1.3	R481D	Pathogenic	0.993
OPA1	O60313-1.3	R481E	Pathogenic	0.938
OPA1	O60313-1.3	R481F	Pathogenic	0.978
OPA1	O60313-1.3	R481G	Pathogenic	0.983
OPA1	O60313-1.3	R481H	Pathogenic	0.885
OPA1	O60313-1.3	R481I	Pathogenic	0.977
OPA1	O60313-1.3	R481K	Pathogenic	0.732
OPA1	O60313-1.3	R481L	Pathogenic	0.94
OPA1	O60313-1.3	R481M	Pathogenic	0.893
OPA1	O60313-1.3	R481N	Pathogenic	0.933
OPA1	O60313-1.3	R481P	Pathogenic	0.972
OPA1	O60313-1.3	R481Q	Pathogenic	0.783
OPA1	O60313-1.3	R481S	Pathogenic	0.957
OPA1	O60313-1.3	R481T	Pathogenic	0.948
OPA1	O60313-1.3	R481V	Pathogenic	0.985
OPA1	O60313-1.3	R481W	Pathogenic	0.966
OPA1	O60313-1.3	R481Y	Pathogenic	0.971
OPA1	O60313-1.3	I482A	Pathogenic	0.569
OPA1	O60313-1.3	I482C	Pathogenic	0.725
OPA1	O60313-1.3	I482D	Pathogenic	0.819
OPA1	O60313-1.3	I482E	Pathogenic	0.845
OPA1	O60313-1.3	I482F	Pathogenic	0.678
OPA1	O60313-1.3	I482G	Pathogenic	0.958
OPA1	O60313-1.3	I482H	Pathogenic	0.92
OPA1	O60313-1.3	I482K	Pathogenic	0.801
OPA1	O60313-1.3	I482L	Neutral	0.194
OPA1	O60313-1.3	I482M	Neutral	0.312
OPA1	O60313-1.3	I482N	Pathogenic	0.843
OPA1	O60313-1.3	I482P	Pathogenic	0.946
OPA1	O60313-1.3	I482Q	Pathogenic	0.891
OPA1	O60313-1.3	I482R	Pathogenic	0.791
OPA1	O60313-1.3	I482S	Pathogenic	0.741
OPA1	O60313-1.3	I482T	Pathogenic	0.582
OPA1	O60313-1.3	I482V	Neutral	0.047
OPA1	O60313-1.3	I482W	Pathogenic	0.969
OPA1	O60313-1.3	I482Y	Pathogenic	0.736
OPA1	O60313-1.3	Q483A	Pathogenic	0.681
OPA1	O60313-1.3	Q483C	Pathogenic	0.912
OPA1	O60313-1.3	Q483D	Neutral	0.441
OPA1	O60313-1.3	Q483E	Neutral	0.102
OPA1	O60313-1.3	Q483F	Pathogenic	0.836
OPA1	O60313-1.3	Q483G	Pathogenic	0.884
OPA1	O60313-1.3	Q483H	Pathogenic	0.503
OPA1	O60313-1.3	Q483I	Pathogenic	0.84
OPA1	O60313-1.3	Q483K	Neutral	0.183
OPA1	O60313-1.3	Q483L	Pathogenic	0.665
OPA1	O60313-1.3	Q483M	Neutral	0.266
OPA1	O60313-1.3	Q483N	Neutral	0.484
OPA1	O60313-1.3	Q483P	Pathogenic	0.615
OPA1	O60313-1.3	Q483R	Neutral	0.174
OPA1	O60313-1.3	Q483S	Pathogenic	0.507
OPA1	O60313-1.3	Q483T	Pathogenic	0.711
OPA1	O60313-1.3	Q483V	Pathogenic	0.756
OPA1	O60313-1.3	Q483W	Pathogenic	0.509
OPA1	O60313-1.3	Q483Y	Pathogenic	0.558
OPA1	O60313-1.3	Q484A	Pathogenic	0.739
OPA1	O60313-1.3	Q484C	Pathogenic	0.932
OPA1	O60313-1.3	Q484D	Pathogenic	0.511
OPA1	O60313-1.3	Q484E	Neutral	0.131
OPA1	O60313-1.3	Q484F	Pathogenic	0.871
OPA1	O60313-1.3	Q484G	Pathogenic	0.91
OPA1	O60313-1.3	Q484H	Pathogenic	0.574
OPA1	O60313-1.3	Q484I	Pathogenic	0.874
OPA1	O60313-1.3	Q484K	Neutral	0.229
OPA1	O60313-1.3	Q484L	Pathogenic	0.725
OPA1	O60313-1.3	Q484M	Neutral	0.325
OPA1	O60313-1.3	Q484N	Pathogenic	0.554
OPA1	O60313-1.3	Q484P	Pathogenic	0.679
OPA1	O60313-1.3	Q484R	Neutral	0.218
OPA1	O60313-1.3	Q484S	Pathogenic	0.578
OPA1	O60313-1.3	Q484T	Pathogenic	0.766
OPA1	O60313-1.3	Q484V	Pathogenic	0.804
OPA1	O60313-1.3	Q484W	Pathogenic	0.579
OPA1	O60313-1.3	Q484Y	Pathogenic	0.626
OPA1	O60313-1.3	I485A	Pathogenic	0.941
OPA1	O60313-1.3	I485C	Pathogenic	0.969
OPA1	O60313-1.3	I485D	Pathogenic	0.982
OPA1	O60313-1.3	I485E	Pathogenic	0.985
OPA1	O60313-1.3	I485F	Pathogenic	0.962
OPA1	O60313-1.3	I485G	Pathogenic	0.996
OPA1	O60313-1.3	I485H	Pathogenic	0.993
OPA1	O60313-1.3	I485K	Pathogenic	0.98
OPA1	O60313-1.3	I485L	Pathogenic	0.743
OPA1	O60313-1.3	I485M	Pathogenic	0.845
OPA1	O60313-1.3	I485N	Pathogenic	0.985
OPA1	O60313-1.3	I485P	Pathogenic	0.995
OPA1	O60313-1.3	I485Q	Pathogenic	0.99
OPA1	O60313-1.3	I485R	Pathogenic	0.978
OPA1	O60313-1.3	I485S	Pathogenic	0.972
OPA1	O60313-1.3	I485T	Pathogenic	0.944
OPA1	O60313-1.3	I485V	Neutral	0.373
OPA1	O60313-1.3	I485W	Pathogenic	0.997
OPA1	O60313-1.3	I485Y	Pathogenic	0.971
OPA1	O60313-1.3	I486A	Neutral	0.118
OPA1	O60313-1.3	I486C	Neutral	0.211
OPA1	O60313-1.3	I486D	Neutral	0.315
OPA1	O60313-1.3	I486E	Neutral	0.357
OPA1	O60313-1.3	I486F	Neutral	0.176
OPA1	O60313-1.3	I486G	Pathogenic	0.697
OPA1	O60313-1.3	I486H	Pathogenic	0.538
OPA1	O60313-1.3	I486K	Neutral	0.29
OPA1	O60313-1.3	I486L	Neutral	0.024
OPA1	O60313-1.3	I486M	Neutral	0.044
OPA1	O60313-1.3	I486N	Neutral	0.354
OPA1	O60313-1.3	I486P	Pathogenic	0.642
OPA1	O60313-1.3	I486Q	Neutral	0.453
OPA1	O60313-1.3	I486R	Neutral	0.277
OPA1	O60313-1.3	I486S	Neutral	0.225
OPA1	O60313-1.3	I486T	Neutral	0.124
OPA1	O60313-1.3	I486V	Neutral	0.005
OPA1	O60313-1.3	I486W	Pathogenic	0.759
OPA1	O60313-1.3	I486Y	Neutral	0.221
OPA1	O60313-1.3	E487A	Neutral	0.431
OPA1	O60313-1.3	E487C	Pathogenic	0.915
OPA1	O60313-1.3	E487D	Neutral	0.067
OPA1	O60313-1.3	E487F	Pathogenic	0.636
OPA1	O60313-1.3	E487G	Pathogenic	0.731
OPA1	O60313-1.3	E487H	Neutral	0.258
OPA1	O60313-1.3	E487I	Pathogenic	0.642
OPA1	O60313-1.3	E487K	Neutral	0.142
OPA1	O60313-1.3	E487L	Pathogenic	0.663
OPA1	O60313-1.3	E487M	Pathogenic	0.511
OPA1	O60313-1.3	E487N	Neutral	0.401
OPA1	O60313-1.3	E487P	Neutral	0.362
OPA1	O60313-1.3	E487Q	Neutral	0.055
OPA1	O60313-1.3	E487R	Neutral	0.31
OPA1	O60313-1.3	E487S	Neutral	0.268
OPA1	O60313-1.3	E487T	Neutral	0.467
OPA1	O60313-1.3	E487V	Pathogenic	0.524
OPA1	O60313-1.3	E487W	Pathogenic	0.507
OPA1	O60313-1.3	E487Y	Pathogenic	0.557
OPA1	O60313-1.3	G488A	Pathogenic	0.955
OPA1	O60313-1.3	G488C	Pathogenic	0.996
OPA1	O60313-1.3	G488D	Pathogenic	0.973
OPA1	O60313-1.3	G488E	Pathogenic	0.991
OPA1	O60313-1.3	G488F	Pathogenic	0.99
OPA1	O60313-1.3	G488H	Pathogenic	0.994
OPA1	O60313-1.3	G488I	Pathogenic	0.997
OPA1	O60313-1.3	G488K	Pathogenic	0.987
OPA1	O60313-1.3	G488L	Pathogenic	0.997
OPA1	O60313-1.3	G488M	Pathogenic	0.994
OPA1	O60313-1.3	G488N	Pathogenic	0.935
OPA1	O60313-1.3	G488P	Pathogenic	0.991
OPA1	O60313-1.3	G488Q	Pathogenic	0.994
OPA1	O60313-1.3	G488R	Pathogenic	0.986
OPA1	O60313-1.3	G488S	Pathogenic	0.964
OPA1	O60313-1.3	G488T	Pathogenic	0.994
OPA1	O60313-1.3	G488V	Pathogenic	0.995
OPA1	O60313-1.3	G488W	Pathogenic	0.954
OPA1	O60313-1.3	G488Y	Pathogenic	0.995
OPA1	O60313-1.3	K489A	Pathogenic	0.956
OPA1	O60313-1.3	K489C	Pathogenic	0.991
OPA1	O60313-1.3	K489D	Pathogenic	0.985
OPA1	O60313-1.3	K489E	Pathogenic	0.879
OPA1	O60313-1.3	K489F	Pathogenic	0.984
OPA1	O60313-1.3	K489G	Pathogenic	0.987
OPA1	O60313-1.3	K489H	Pathogenic	0.969
OPA1	O60313-1.3	K489I	Pathogenic	0.983
OPA1	O60313-1.3	K489L	Pathogenic	0.956
OPA1	O60313-1.3	K489M	Pathogenic	0.921
OPA1	O60313-1.3	K489N	Pathogenic	0.951
OPA1	O60313-1.3	K489P	Pathogenic	0.943
OPA1	O60313-1.3	K489Q	Pathogenic	0.834
OPA1	O60313-1.3	K489R	Pathogenic	0.781
OPA1	O60313-1.3	K489S	Pathogenic	0.914
OPA1	O60313-1.3	K489T	Pathogenic	0.962
OPA1	O60313-1.3	K489V	Pathogenic	0.97
OPA1	O60313-1.3	K489W	Pathogenic	0.973
OPA1	O60313-1.3	K489Y	Pathogenic	0.978
OPA1	O60313-1.3	L490A	Pathogenic	0.929
OPA1	O60313-1.3	L490C	Pathogenic	0.963
OPA1	O60313-1.3	L490D	Pathogenic	0.992
OPA1	O60313-1.3	L490E	Pathogenic	0.982
OPA1	O60313-1.3	L490F	Pathogenic	0.947
OPA1	O60313-1.3	L490G	Pathogenic	0.996
OPA1	O60313-1.3	L490H	Pathogenic	0.991
OPA1	O60313-1.3	L490I	Pathogenic	0.684
OPA1	O60313-1.3	L490K	Pathogenic	0.932
OPA1	O60313-1.3	L490M	Pathogenic	0.608
OPA1	O60313-1.3	L490N	Pathogenic	0.982
OPA1	O60313-1.3	L490P	Pathogenic	0.994
OPA1	O60313-1.3	L490Q	Pathogenic	0.965
OPA1	O60313-1.3	L490R	Pathogenic	0.928
OPA1	O60313-1.3	L490S	Pathogenic	0.966
OPA1	O60313-1.3	L490T	Pathogenic	0.932
OPA1	O60313-1.3	L490V	Pathogenic	0.805
OPA1	O60313-1.3	L490W	Pathogenic	0.989
OPA1	O60313-1.3	L490Y	Pathogenic	0.965
OPA1	O60313-1.3	F491A	Pathogenic	0.982
OPA1	O60313-1.3	F491C	Pathogenic	0.991
OPA1	O60313-1.3	F491D	Pathogenic	0.984
OPA1	O60313-1.3	F491E	Pathogenic	0.987
OPA1	O60313-1.3	F491G	Pathogenic	0.991
OPA1	O60313-1.3	F491H	Pathogenic	0.95
OPA1	O60313-1.3	F491I	Pathogenic	0.968
OPA1	O60313-1.3	F491K	Pathogenic	0.984
OPA1	O60313-1.3	F491L	Pathogenic	0.966
OPA1	O60313-1.3	F491M	Pathogenic	0.948
OPA1	O60313-1.3	F491N	Pathogenic	0.987
OPA1	O60313-1.3	F491P	Pathogenic	0.999
OPA1	O60313-1.3	F491Q	Pathogenic	0.991
OPA1	O60313-1.3	F491R	Pathogenic	0.983
OPA1	O60313-1.3	F491S	Pathogenic	0.976
OPA1	O60313-1.3	F491T	Pathogenic	0.983
OPA1	O60313-1.3	F491V	Pathogenic	0.98
OPA1	O60313-1.3	F491W	Pathogenic	0.866
OPA1	O60313-1.3	F491Y	Neutral	0.374
OPA1	O60313-1.3	P492A	Pathogenic	0.983
OPA1	O60313-1.3	P492C	Pathogenic	0.998
OPA1	O60313-1.3	P492D	Pathogenic	0.96
OPA1	O60313-1.3	P492E	Pathogenic	0.962
OPA1	O60313-1.3	P492F	Pathogenic	0.999
OPA1	O60313-1.3	P492G	Pathogenic	0.992
OPA1	O60313-1.3	P492H	Pathogenic	0.993
OPA1	O60313-1.3	P492I	Pathogenic	0.996
OPA1	O60313-1.3	P492K	Pathogenic	0.943
OPA1	O60313-1.3	P492L	Pathogenic	0.996
OPA1	O60313-1.3	P492M	Pathogenic	0.993
OPA1	O60313-1.3	P492N	Pathogenic	0.988
OPA1	O60313-1.3	P492Q	Pathogenic	0.973
OPA1	O60313-1.3	P492R	Pathogenic	0.978
OPA1	O60313-1.3	P492S	Pathogenic	0.978
OPA1	O60313-1.3	P492T	Pathogenic	0.984
OPA1	O60313-1.3	P492V	Pathogenic	0.994
OPA1	O60313-1.3	P492W	Pathogenic	0.998
OPA1	O60313-1.3	P492Y	Pathogenic	0.998
OPA1	O60313-1.3	M493A	Pathogenic	0.974
OPA1	O60313-1.3	M493C	Pathogenic	0.987
OPA1	O60313-1.3	M493D	Pathogenic	0.992
OPA1	O60313-1.3	M493E	Pathogenic	0.982
OPA1	O60313-1.3	M493F	Pathogenic	0.956
OPA1	O60313-1.3	M493G	Pathogenic	0.996
OPA1	O60313-1.3	M493H	Pathogenic	0.991
OPA1	O60313-1.3	M493I	Pathogenic	0.884
OPA1	O60313-1.3	M493K	Pathogenic	0.932
OPA1	O60313-1.3	M493L	Pathogenic	0.743
OPA1	O60313-1.3	M493N	Pathogenic	0.981
OPA1	O60313-1.3	M493P	Pathogenic	0.994
OPA1	O60313-1.3	M493Q	Pathogenic	0.905
OPA1	O60313-1.3	M493R	Pathogenic	0.928
OPA1	O60313-1.3	M493S	Pathogenic	0.966
OPA1	O60313-1.3	M493T	Pathogenic	0.975
OPA1	O60313-1.3	M493V	Pathogenic	0.922
OPA1	O60313-1.3	M493W	Pathogenic	0.974
OPA1	O60313-1.3	M493Y	Pathogenic	0.988
OPA1	O60313-1.3	K494A	Pathogenic	0.938
OPA1	O60313-1.3	K494C	Pathogenic	0.987
OPA1	O60313-1.3	K494D	Pathogenic	0.978
OPA1	O60313-1.3	K494E	Pathogenic	0.832
OPA1	O60313-1.3	K494F	Pathogenic	0.977
OPA1	O60313-1.3	K494G	Pathogenic	0.982
OPA1	O60313-1.3	K494H	Pathogenic	0.955
OPA1	O60313-1.3	K494I	Pathogenic	0.975
OPA1	O60313-1.3	K494L	Pathogenic	0.938
OPA1	O60313-1.3	K494M	Pathogenic	0.889
OPA1	O60313-1.3	K494N	Pathogenic	0.93
OPA1	O60313-1.3	K494P	Pathogenic	0.918
OPA1	O60313-1.3	K494Q	Pathogenic	0.775
OPA1	O60313-1.3	K494R	Pathogenic	0.71
OPA1	O60313-1.3	K494S	Pathogenic	0.879
OPA1	O60313-1.3	K494T	Pathogenic	0.945
OPA1	O60313-1.3	K494V	Pathogenic	0.956
OPA1	O60313-1.3	K494W	Pathogenic	0.961
OPA1	O60313-1.3	K494Y	Pathogenic	0.968
OPA1	O60313-1.3	A495C	Pathogenic	0.928
OPA1	O60313-1.3	A495D	Pathogenic	0.987
OPA1	O60313-1.3	A495E	Pathogenic	0.964
OPA1	O60313-1.3	A495F	Pathogenic	0.977
OPA1	O60313-1.3	A495G	Pathogenic	0.947
OPA1	O60313-1.3	A495H	Pathogenic	0.993
OPA1	O60313-1.3	A495I	Pathogenic	0.939
OPA1	O60313-1.3	A495K	Pathogenic	0.946
OPA1	O60313-1.3	A495L	Pathogenic	0.944
OPA1	O60313-1.3	A495M	Pathogenic	0.963
OPA1	O60313-1.3	A495N	Pathogenic	0.988
OPA1	O60313-1.3	A495P	Pathogenic	0.979
OPA1	O60313-1.3	A495Q	Pathogenic	0.975
OPA1	O60313-1.3	A495R	Pathogenic	0.943
OPA1	O60313-1.3	A495S	Pathogenic	0.863
OPA1	O60313-1.3	A495T	Pathogenic	0.957
OPA1	O60313-1.3	A495V	Pathogenic	0.906
OPA1	O60313-1.3	A495W	Pathogenic	0.987
OPA1	O60313-1.3	A495Y	Pathogenic	0.989
OPA1	O60313-1.3	L496A	Pathogenic	0.929
OPA1	O60313-1.3	L496C	Pathogenic	0.963
OPA1	O60313-1.3	L496D	Pathogenic	0.992
OPA1	O60313-1.3	L496E	Pathogenic	0.982
OPA1	O60313-1.3	L496F	Pathogenic	0.947
OPA1	O60313-1.3	L496G	Pathogenic	0.996
OPA1	O60313-1.3	L496H	Pathogenic	0.991
OPA1	O60313-1.3	L496I	Pathogenic	0.684
OPA1	O60313-1.3	L496K	Pathogenic	0.932
OPA1	O60313-1.3	L496M	Pathogenic	0.608
OPA1	O60313-1.3	L496N	Pathogenic	0.982
OPA1	O60313-1.3	L496P	Pathogenic	0.994
OPA1	O60313-1.3	L496Q	Pathogenic	0.965
OPA1	O60313-1.3	L496R	Pathogenic	0.928
OPA1	O60313-1.3	L496S	Pathogenic	0.966
OPA1	O60313-1.3	L496T	Pathogenic	0.932
OPA1	O60313-1.3	L496V	Pathogenic	0.805
OPA1	O60313-1.3	L496W	Pathogenic	0.989
OPA1	O60313-1.3	L496Y	Pathogenic	0.965
OPA1	O60313-1.3	G497A	Pathogenic	0.975
OPA1	O60313-1.3	G497C	Pathogenic	0.998
OPA1	O60313-1.3	G497D	Pathogenic	0.985
OPA1	O60313-1.3	G497E	Pathogenic	0.995
OPA1	O60313-1.3	G497F	Pathogenic	0.995
OPA1	O60313-1.3	G497H	Pathogenic	0.997
OPA1	O60313-1.3	G497I	Pathogenic	0.998
OPA1	O60313-1.3	G497K	Pathogenic	0.993
OPA1	O60313-1.3	G497L	Pathogenic	0.998
OPA1	O60313-1.3	G497M	Pathogenic	0.997
OPA1	O60313-1.3	G497N	Pathogenic	0.964
OPA1	O60313-1.3	G497P	Pathogenic	0.995
OPA1	O60313-1.3	G497Q	Pathogenic	0.997
OPA1	O60313-1.3	G497R	Pathogenic	0.992
OPA1	O60313-1.3	G497S	Pathogenic	0.98
OPA1	O60313-1.3	G497T	Pathogenic	0.997
OPA1	O60313-1.3	G497V	Pathogenic	0.997
OPA1	O60313-1.3	G497W	Pathogenic	0.975
OPA1	O60313-1.3	G497Y	Pathogenic	0.997
OPA1	O60313-1.3	Y498A	Pathogenic	0.992
OPA1	O60313-1.3	Y498C	Pathogenic	0.996
OPA1	O60313-1.3	Y498D	Pathogenic	0.993
OPA1	O60313-1.3	Y498E	Pathogenic	0.984
OPA1	O60313-1.3	Y498F	Neutral	0.403
OPA1	O60313-1.3	Y498G	Pathogenic	0.996
OPA1	O60313-1.3	Y498H	Pathogenic	0.648
OPA1	O60313-1.3	Y498I	Pathogenic	0.978
OPA1	O60313-1.3	Y498K	Pathogenic	0.98
OPA1	O60313-1.3	Y498L	Pathogenic	0.98
OPA1	O60313-1.3	Y498M	Pathogenic	0.987
OPA1	O60313-1.3	Y498N	Pathogenic	0.984
OPA1	O60313-1.3	Y498P	Pathogenic	0.998
OPA1	O60313-1.3	Y498Q	Pathogenic	0.97
OPA1	O60313-1.3	Y498R	Pathogenic	0.98
OPA1	O60313-1.3	Y498S	Pathogenic	0.989
OPA1	O60313-1.3	Y498T	Pathogenic	0.993
OPA1	O60313-1.3	Y498V	Pathogenic	0.986
OPA1	O60313-1.3	Y498W	Pathogenic	0.547
OPA1	O60313-1.3	F499A	Pathogenic	0.958
OPA1	O60313-1.3	F499C	Pathogenic	0.978
OPA1	O60313-1.3	F499D	Pathogenic	0.964
OPA1	O60313-1.3	F499E	Pathogenic	0.97
OPA1	O60313-1.3	F499G	Pathogenic	0.979
OPA1	O60313-1.3	F499H	Pathogenic	0.889
OPA1	O60313-1.3	F499I	Pathogenic	0.927
OPA1	O60313-1.3	F499K	Pathogenic	0.963
OPA1	O60313-1.3	F499L	Pathogenic	0.923
OPA1	O60313-1.3	F499M	Pathogenic	0.886
OPA1	O60313-1.3	F499N	Pathogenic	0.97
OPA1	O60313-1.3	F499P	Pathogenic	0.997
OPA1	O60313-1.3	F499Q	Pathogenic	0.98
OPA1	O60313-1.3	F499R	Pathogenic	0.96
OPA1	O60313-1.3	F499S	Pathogenic	0.944
OPA1	O60313-1.3	F499T	Pathogenic	0.96
OPA1	O60313-1.3	F499V	Pathogenic	0.954
OPA1	O60313-1.3	F499W	Pathogenic	0.733
OPA1	O60313-1.3	F499Y	Neutral	0.202
OPA1	O60313-1.3	A500C	Pathogenic	0.928
OPA1	O60313-1.3	A500D	Pathogenic	0.987
OPA1	O60313-1.3	A500E	Pathogenic	0.964
OPA1	O60313-1.3	A500F	Pathogenic	0.977
OPA1	O60313-1.3	A500G	Pathogenic	0.947
OPA1	O60313-1.3	A500H	Pathogenic	0.993
OPA1	O60313-1.3	A500I	Pathogenic	0.939
OPA1	O60313-1.3	A500K	Pathogenic	0.946
OPA1	O60313-1.3	A500L	Pathogenic	0.944
OPA1	O60313-1.3	A500M	Pathogenic	0.963
OPA1	O60313-1.3	A500N	Pathogenic	0.988
OPA1	O60313-1.3	A500P	Pathogenic	0.979
OPA1	O60313-1.3	A500Q	Pathogenic	0.975
OPA1	O60313-1.3	A500R	Pathogenic	0.943
OPA1	O60313-1.3	A500S	Pathogenic	0.863
OPA1	O60313-1.3	A500T	Pathogenic	0.957
OPA1	O60313-1.3	A500V	Pathogenic	0.906
OPA1	O60313-1.3	A500W	Pathogenic	0.987
OPA1	O60313-1.3	A500Y	Pathogenic	0.989
OPA1	O60313-1.3	V501A	Pathogenic	0.902
OPA1	O60313-1.3	V501C	Pathogenic	0.982
OPA1	O60313-1.3	V501D	Pathogenic	0.989
OPA1	O60313-1.3	V501E	Pathogenic	0.974
OPA1	O60313-1.3	V501F	Pathogenic	0.974
OPA1	O60313-1.3	V501G	Pathogenic	0.994
OPA1	O60313-1.3	V501H	Pathogenic	0.995
OPA1	O60313-1.3	V501I	Neutral	0.354
OPA1	O60313-1.3	V501K	Pathogenic	0.961
OPA1	O60313-1.3	V501L	Pathogenic	0.835
OPA1	O60313-1.3	V501M	Pathogenic	0.886
OPA1	O60313-1.3	V501N	Pathogenic	0.991
OPA1	O60313-1.3	V501P	Pathogenic	0.992
OPA1	O60313-1.3	V501Q	Pathogenic	0.982
OPA1	O60313-1.3	V501R	Pathogenic	0.985
OPA1	O60313-1.3	V501S	Pathogenic	0.983
OPA1	O60313-1.3	V501T	Pathogenic	0.907
OPA1	O60313-1.3	V501W	Pathogenic	0.995
OPA1	O60313-1.3	V501Y	Pathogenic	0.98
OPA1	O60313-1.3	V502A	Pathogenic	0.902
OPA1	O60313-1.3	V502C	Pathogenic	0.982
OPA1	O60313-1.3	V502D	Pathogenic	0.989
OPA1	O60313-1.3	V502E	Pathogenic	0.974
OPA1	O60313-1.3	V502F	Pathogenic	0.974
OPA1	O60313-1.3	V502G	Pathogenic	0.994
OPA1	O60313-1.3	V502H	Pathogenic	0.995
OPA1	O60313-1.3	V502I	Neutral	0.354
OPA1	O60313-1.3	V502K	Pathogenic	0.961
OPA1	O60313-1.3	V502L	Pathogenic	0.835
OPA1	O60313-1.3	V502M	Pathogenic	0.886
OPA1	O60313-1.3	V502N	Pathogenic	0.991
OPA1	O60313-1.3	V502P	Pathogenic	0.992
OPA1	O60313-1.3	V502Q	Pathogenic	0.982
OPA1	O60313-1.3	V502R	Pathogenic	0.985
OPA1	O60313-1.3	V502S	Pathogenic	0.983
OPA1	O60313-1.3	V502T	Pathogenic	0.907
OPA1	O60313-1.3	V502W	Pathogenic	0.995
OPA1	O60313-1.3	V502Y	Pathogenic	0.98
OPA1	O60313-1.3	T503A	Pathogenic	0.958
OPA1	O60313-1.3	T503C	Pathogenic	0.975
OPA1	O60313-1.3	T503D	Pathogenic	0.968
OPA1	O60313-1.3	T503E	Pathogenic	0.97
OPA1	O60313-1.3	T503F	Pathogenic	0.979
OPA1	O60313-1.3	T503G	Pathogenic	0.993
OPA1	O60313-1.3	T503H	Pathogenic	0.995
OPA1	O60313-1.3	T503I	Pathogenic	0.943
OPA1	O60313-1.3	T503K	Pathogenic	0.955
OPA1	O60313-1.3	T503L	Pathogenic	0.948
OPA1	O60313-1.3	T503M	Pathogenic	0.966
OPA1	O60313-1.3	T503N	Pathogenic	0.923
OPA1	O60313-1.3	T503P	Pathogenic	0.98
OPA1	O60313-1.3	T503Q	Pathogenic	0.979
OPA1	O60313-1.3	T503R	Pathogenic	0.952
OPA1	O60313-1.3	T503S	Pathogenic	0.867
OPA1	O60313-1.3	T503V	Pathogenic	0.913
OPA1	O60313-1.3	T503W	Pathogenic	0.965
OPA1	O60313-1.3	T503Y	Pathogenic	0.99
OPA1	O60313-1.3	G504A	Pathogenic	0.955
OPA1	O60313-1.3	G504C	Pathogenic	0.996
OPA1	O60313-1.3	G504D	Pathogenic	0.973
OPA1	O60313-1.3	G504E	Pathogenic	0.991
OPA1	O60313-1.3	G504F	Pathogenic	0.99
OPA1	O60313-1.3	G504H	Pathogenic	0.994
OPA1	O60313-1.3	G504I	Pathogenic	0.997
OPA1	O60313-1.3	G504K	Pathogenic	0.987
OPA1	O60313-1.3	G504L	Pathogenic	0.997
OPA1	O60313-1.3	G504M	Pathogenic	0.994
OPA1	O60313-1.3	G504N	Pathogenic	0.935
OPA1	O60313-1.3	G504P	Pathogenic	0.991
OPA1	O60313-1.3	G504Q	Pathogenic	0.994
OPA1	O60313-1.3	G504R	Pathogenic	0.986
OPA1	O60313-1.3	G504S	Pathogenic	0.964
OPA1	O60313-1.3	G504T	Pathogenic	0.994
OPA1	O60313-1.3	G504V	Pathogenic	0.995
OPA1	O60313-1.3	G504W	Pathogenic	0.954
OPA1	O60313-1.3	G504Y	Pathogenic	0.995
OPA1	O60313-1.3	K505A	Pathogenic	0.658
OPA1	O60313-1.3	K505C	Pathogenic	0.904
OPA1	O60313-1.3	K505D	Pathogenic	0.849
OPA1	O60313-1.3	K505E	Neutral	0.389
OPA1	O60313-1.3	K505F	Pathogenic	0.843
OPA1	O60313-1.3	K505G	Pathogenic	0.873
OPA1	O60313-1.3	K505H	Pathogenic	0.732
OPA1	O60313-1.3	K505I	Pathogenic	0.836
OPA1	O60313-1.3	K505L	Pathogenic	0.659
OPA1	O60313-1.3	K505M	Pathogenic	0.505
OPA1	O60313-1.3	K505N	Pathogenic	0.63
OPA1	O60313-1.3	K505P	Pathogenic	0.59
OPA1	O60313-1.3	K505Q	Neutral	0.307
OPA1	O60313-1.3	K505R	Neutral	0.239
OPA1	O60313-1.3	K505S	Neutral	0.482
OPA1	O60313-1.3	K505T	Pathogenic	0.69
OPA1	O60313-1.3	K505V	Pathogenic	0.737
OPA1	O60313-1.3	K505W	Pathogenic	0.76
OPA1	O60313-1.3	K505Y	Pathogenic	0.795
OPA1	O60313-1.3	G506A	Pathogenic	0.953
OPA1	O60313-1.3	G506C	Pathogenic	0.996
OPA1	O60313-1.3	G506D	Pathogenic	0.972
OPA1	O60313-1.3	G506E	Pathogenic	0.991
OPA1	O60313-1.3	G506F	Pathogenic	0.99
OPA1	O60313-1.3	G506H	Pathogenic	0.994
OPA1	O60313-1.3	G506I	Pathogenic	0.997
OPA1	O60313-1.3	G506K	Pathogenic	0.986
OPA1	O60313-1.3	G506L	Pathogenic	0.997
OPA1	O60313-1.3	G506M	Pathogenic	0.994
OPA1	O60313-1.3	G506N	Pathogenic	0.932
OPA1	O60313-1.3	G506P	Pathogenic	0.991
OPA1	O60313-1.3	G506Q	Pathogenic	0.994
OPA1	O60313-1.3	G506R	Pathogenic	0.985
OPA1	O60313-1.3	G506S	Pathogenic	0.962
OPA1	O60313-1.3	G506T	Pathogenic	0.994
OPA1	O60313-1.3	G506V	Pathogenic	0.995
OPA1	O60313-1.3	G506W	Pathogenic	0.952
OPA1	O60313-1.3	G506Y	Pathogenic	0.995
OPA1	O60313-1.3	N507A	Neutral	0.356
OPA1	O60313-1.3	N507C	Neutral	0.481
OPA1	O60313-1.3	N507D	Neutral	0.047
OPA1	O60313-1.3	N507E	Neutral	0.134
OPA1	O60313-1.3	N507F	Neutral	0.285
OPA1	O60313-1.3	N507G	Neutral	0.075
OPA1	O60313-1.3	N507H	Neutral	0.027
OPA1	O60313-1.3	N507I	Neutral	0.29
OPA1	O60313-1.3	N507K	Neutral	0.093
OPA1	O60313-1.3	N507L	Neutral	0.31
OPA1	O60313-1.3	N507M	Neutral	0.192
OPA1	O60313-1.3	N507P	Neutral	0.293
OPA1	O60313-1.3	N507Q	Neutral	0.1
OPA1	O60313-1.3	N507R	Neutral	0.087
OPA1	O60313-1.3	N507S	Neutral	0.031
OPA1	O60313-1.3	N507T	Neutral	0.071
OPA1	O60313-1.3	N507V	Neutral	0.429
OPA1	O60313-1.3	N507W	Neutral	0.405
OPA1	O60313-1.3	N507Y	Neutral	0.223
OPA1	O60313-1.3	S508A	Neutral	0.021
OPA1	O60313-1.3	S508C	Neutral	0.087
OPA1	O60313-1.3	S508D	Neutral	0.04
OPA1	O60313-1.3	S508E	Neutral	0.042
OPA1	O60313-1.3	S508F	Neutral	0.099
OPA1	O60313-1.3	S508G	Neutral	0.072
OPA1	O60313-1.3	S508H	Neutral	0.156
OPA1	O60313-1.3	S508I	Neutral	0.102
OPA1	O60313-1.3	S508K	Neutral	0.028
OPA1	O60313-1.3	S508L	Neutral	0.111
OPA1	O60313-1.3	S508M	Neutral	0.062
OPA1	O60313-1.3	S508N	Neutral	0.016
OPA1	O60313-1.3	S508P	Neutral	0.107
OPA1	O60313-1.3	S508Q	Neutral	0.06
OPA1	O60313-1.3	S508R	Neutral	0.073
OPA1	O60313-1.3	S508T	Neutral	0.021
OPA1	O60313-1.3	S508V	Neutral	0.172
OPA1	O60313-1.3	S508W	Neutral	0.159
OPA1	O60313-1.3	S508Y	Neutral	0.187
OPA1	O60313-1.3	S509A	Neutral	0.01
OPA1	O60313-1.3	S509C	Neutral	0.044
OPA1	O60313-1.3	S509D	Neutral	0.02
OPA1	O60313-1.3	S509E	Neutral	0.021
OPA1	O60313-1.3	S509F	Neutral	0.051
OPA1	O60313-1.3	S509G	Neutral	0.036
OPA1	O60313-1.3	S509H	Neutral	0.082
OPA1	O60313-1.3	S509I	Neutral	0.052
OPA1	O60313-1.3	S509K	Neutral	0.014
OPA1	O60313-1.3	S509L	Neutral	0.057
OPA1	O60313-1.3	S509M	Neutral	0.031
OPA1	O60313-1.3	S509N	Neutral	0.008
OPA1	O60313-1.3	S509P	Neutral	0.055
OPA1	O60313-1.3	S509Q	Neutral	0.03
OPA1	O60313-1.3	S509R	Neutral	0.037
OPA1	O60313-1.3	S509T	Neutral	0.01
OPA1	O60313-1.3	S509V	Neutral	0.092
OPA1	O60313-1.3	S509W	Neutral	0.084
OPA1	O60313-1.3	S509Y	Neutral	0.101
OPA1	O60313-1.3	E510A	Pathogenic	0.613
OPA1	O60313-1.3	E510C	Pathogenic	0.957
OPA1	O60313-1.3	E510D	Neutral	0.13
OPA1	O60313-1.3	E510F	Pathogenic	0.785
OPA1	O60313-1.3	E510G	Pathogenic	0.85
OPA1	O60313-1.3	E510H	Neutral	0.42
OPA1	O60313-1.3	E510I	Pathogenic	0.789
OPA1	O60313-1.3	E510K	Neutral	0.256
OPA1	O60313-1.3	E510L	Pathogenic	0.804
OPA1	O60313-1.3	E510M	Pathogenic	0.685
OPA1	O60313-1.3	E510N	Pathogenic	0.583
OPA1	O60313-1.3	E510P	Pathogenic	0.542
OPA1	O60313-1.3	E510Q	Neutral	0.108
OPA1	O60313-1.3	E510R	Neutral	0.484
OPA1	O60313-1.3	E510S	Neutral	0.434
OPA1	O60313-1.3	E510T	Pathogenic	0.646
OPA1	O60313-1.3	E510V	Pathogenic	0.697
OPA1	O60313-1.3	E510W	Pathogenic	0.682
OPA1	O60313-1.3	E510Y	Pathogenic	0.724
OPA1	O60313-1.3	S511A	Pathogenic	0.557
OPA1	O60313-1.3	S511C	Pathogenic	0.847
OPA1	O60313-1.3	S511D	Pathogenic	0.71
OPA1	O60313-1.3	S511E	Pathogenic	0.72
OPA1	O60313-1.3	S511F	Pathogenic	0.865
OPA1	O60313-1.3	S511G	Pathogenic	0.818
OPA1	O60313-1.3	S511H	Pathogenic	0.915
OPA1	O60313-1.3	S511I	Pathogenic	0.868
OPA1	O60313-1.3	S511K	Pathogenic	0.629
OPA1	O60313-1.3	S511L	Pathogenic	0.879
OPA1	O60313-1.3	S511M	Pathogenic	0.793
OPA1	O60313-1.3	S511N	Neutral	0.491
OPA1	O60313-1.3	S511P	Pathogenic	0.874
OPA1	O60313-1.3	S511Q	Pathogenic	0.788
OPA1	O60313-1.3	S511R	Pathogenic	0.822
OPA1	O60313-1.3	S511T	Pathogenic	0.556
OPA1	O60313-1.3	S511V	Pathogenic	0.924
OPA1	O60313-1.3	S511W	Pathogenic	0.916
OPA1	O60313-1.3	S511Y	Pathogenic	0.93
OPA1	O60313-1.3	I512A	Pathogenic	0.941
OPA1	O60313-1.3	I512C	Pathogenic	0.97
OPA1	O60313-1.3	I512D	Pathogenic	0.982
OPA1	O60313-1.3	I512E	Pathogenic	0.985
OPA1	O60313-1.3	I512F	Pathogenic	0.962
OPA1	O60313-1.3	I512G	Pathogenic	0.996
OPA1	O60313-1.3	I512H	Pathogenic	0.993
OPA1	O60313-1.3	I512K	Pathogenic	0.98
OPA1	O60313-1.3	I512L	Pathogenic	0.745
OPA1	O60313-1.3	I512M	Pathogenic	0.847
OPA1	O60313-1.3	I512N	Pathogenic	0.985
OPA1	O60313-1.3	I512P	Pathogenic	0.995
OPA1	O60313-1.3	I512Q	Pathogenic	0.99
OPA1	O60313-1.3	I512R	Pathogenic	0.979
OPA1	O60313-1.3	I512S	Pathogenic	0.972
OPA1	O60313-1.3	I512T	Pathogenic	0.944
OPA1	O60313-1.3	I512V	Neutral	0.376
OPA1	O60313-1.3	I512W	Pathogenic	0.997
OPA1	O60313-1.3	I512Y	Pathogenic	0.971
OPA1	O60313-1.3	E513A	Neutral	0.092
OPA1	O60313-1.3	E513C	Pathogenic	0.589
OPA1	O60313-1.3	E513D	Neutral	0.01
OPA1	O60313-1.3	E513F	Neutral	0.19
OPA1	O60313-1.3	E513G	Neutral	0.267
OPA1	O60313-1.3	E513H	Neutral	0.045
OPA1	O60313-1.3	E513I	Neutral	0.194
OPA1	O60313-1.3	E513K	Neutral	0.022
OPA1	O60313-1.3	E513L	Neutral	0.209
OPA1	O60313-1.3	E513M	Neutral	0.123
OPA1	O60313-1.3	E513N	Neutral	0.082
OPA1	O60313-1.3	E513P	Neutral	0.071
OPA1	O60313-1.3	E513Q	Neutral	0.008
OPA1	O60313-1.3	E513R	Neutral	0.057
OPA1	O60313-1.3	E513S	Neutral	0.047
OPA1	O60313-1.3	E513T	Neutral	0.105
OPA1	O60313-1.3	E513V	Neutral	0.129
OPA1	O60313-1.3	E513W	Neutral	0.121
OPA1	O60313-1.3	E513Y	Neutral	0.144
OPA1	O60313-1.3	A514C	Neutral	0.063
OPA1	O60313-1.3	A514D	Neutral	0.279
OPA1	O60313-1.3	A514E	Neutral	0.123
OPA1	O60313-1.3	A514F	Neutral	0.185
OPA1	O60313-1.3	A514G	Neutral	0.087
OPA1	O60313-1.3	A514H	Neutral	0.444
OPA1	O60313-1.3	A514I	Neutral	0.074
OPA1	O60313-1.3	A514K	Neutral	0.085
OPA1	O60313-1.3	A514L	Neutral	0.081
OPA1	O60313-1.3	A514M	Neutral	0.119
OPA1	O60313-1.3	A514N	Neutral	0.307
OPA1	O60313-1.3	A514P	Neutral	0.198
OPA1	O60313-1.3	A514Q	Neutral	0.168
OPA1	O60313-1.3	A514R	Neutral	0.08
OPA1	O60313-1.3	A514S	Neutral	0.032
OPA1	O60313-1.3	A514T	Neutral	0.105
OPA1	O60313-1.3	A514V	Neutral	0.048
OPA1	O60313-1.3	A514W	Neutral	0.28
OPA1	O60313-1.3	A514Y	Neutral	0.321
OPA1	O60313-1.3	I515A	Pathogenic	0.934
OPA1	O60313-1.3	I515C	Pathogenic	0.966
OPA1	O60313-1.3	I515D	Pathogenic	0.98
OPA1	O60313-1.3	I515E	Pathogenic	0.983
OPA1	O60313-1.3	I515F	Pathogenic	0.958
OPA1	O60313-1.3	I515G	Pathogenic	0.996
OPA1	O60313-1.3	I515H	Pathogenic	0.992
OPA1	O60313-1.3	I515K	Pathogenic	0.977
OPA1	O60313-1.3	I515L	Pathogenic	0.721
OPA1	O60313-1.3	I515M	Pathogenic	0.83
OPA1	O60313-1.3	I515N	Pathogenic	0.983
OPA1	O60313-1.3	I515P	Pathogenic	0.995
OPA1	O60313-1.3	I515Q	Pathogenic	0.989
OPA1	O60313-1.3	I515R	Pathogenic	0.976
OPA1	O60313-1.3	I515S	Pathogenic	0.969
OPA1	O60313-1.3	I515T	Pathogenic	0.937
OPA1	O60313-1.3	I515V	Neutral	0.348
OPA1	O60313-1.3	I515W	Pathogenic	0.997
OPA1	O60313-1.3	I515Y	Pathogenic	0.968
OPA1	O60313-1.3	R516A	Neutral	0.233
OPA1	O60313-1.3	R516C	Pathogenic	0.597
OPA1	O60313-1.3	R516D	Pathogenic	0.721
OPA1	O60313-1.3	R516E	Neutral	0.226
OPA1	O60313-1.3	R516F	Neutral	0.46
OPA1	O60313-1.3	R516G	Pathogenic	0.521
OPA1	O60313-1.3	R516H	Neutral	0.13
OPA1	O60313-1.3	R516I	Neutral	0.446
OPA1	O60313-1.3	R516K	Neutral	0.05
OPA1	O60313-1.3	R516L	Neutral	0.234
OPA1	O60313-1.3	R516M	Neutral	0.139
OPA1	O60313-1.3	R516N	Neutral	0.212
OPA1	O60313-1.3	R516P	Neutral	0.398
OPA1	O60313-1.3	R516Q	Neutral	0.065
OPA1	O60313-1.3	R516S	Neutral	0.299
OPA1	O60313-1.3	R516T	Neutral	0.26
OPA1	O60313-1.3	R516V	Pathogenic	0.562
OPA1	O60313-1.3	R516W	Neutral	0.356
OPA1	O60313-1.3	R516Y	Neutral	0.39
OPA1	O60313-1.3	E517A	Neutral	0.129
OPA1	O60313-1.3	E517C	Pathogenic	0.677
OPA1	O60313-1.3	E517D	Neutral	0.014
OPA1	O60313-1.3	E517F	Neutral	0.255
OPA1	O60313-1.3	E517G	Neutral	0.347
OPA1	O60313-1.3	E517H	Neutral	0.064
OPA1	O60313-1.3	E517I	Neutral	0.26
OPA1	O60313-1.3	E517K	Neutral	0.031
OPA1	O60313-1.3	E517L	Neutral	0.279
OPA1	O60313-1.3	E517M	Neutral	0.17
OPA1	O60313-1.3	E517N	Neutral	0.116
OPA1	O60313-1.3	E517P	Neutral	0.1
OPA1	O60313-1.3	E517Q	Neutral	0.011
OPA1	O60313-1.3	E517R	Neutral	0.081
OPA1	O60313-1.3	E517S	Neutral	0.067
OPA1	O60313-1.3	E517T	Neutral	0.147
OPA1	O60313-1.3	E517V	Neutral	0.178
OPA1	O60313-1.3	E517W	Neutral	0.168
OPA1	O60313-1.3	E517Y	Neutral	0.198
OPA1	O60313-1.3	Y518A	Pathogenic	0.993
OPA1	O60313-1.3	Y518C	Pathogenic	0.996
OPA1	O60313-1.3	Y518D	Pathogenic	0.994
OPA1	O60313-1.3	Y518E	Pathogenic	0.986
OPA1	O60313-1.3	Y518F	Neutral	0.431
OPA1	O60313-1.3	Y518G	Pathogenic	0.997
OPA1	O60313-1.3	Y518H	Pathogenic	0.674
OPA1	O60313-1.3	Y518I	Pathogenic	0.981
OPA1	O60313-1.3	Y518K	Pathogenic	0.982
OPA1	O60313-1.3	Y518L	Pathogenic	0.982
OPA1	O60313-1.3	Y518M	Pathogenic	0.988
OPA1	O60313-1.3	Y518N	Pathogenic	0.986
OPA1	O60313-1.3	Y518P	Pathogenic	0.998
OPA1	O60313-1.3	Y518Q	Pathogenic	0.973
OPA1	O60313-1.3	Y518R	Pathogenic	0.982
OPA1	O60313-1.3	Y518S	Pathogenic	0.991
OPA1	O60313-1.3	Y518T	Pathogenic	0.993
OPA1	O60313-1.3	Y518V	Pathogenic	0.988
OPA1	O60313-1.3	Y518W	Pathogenic	0.576
OPA1	O60313-1.3	E519A	Pathogenic	0.955
OPA1	O60313-1.3	E519C	Pathogenic	0.997
OPA1	O60313-1.3	E519D	Pathogenic	0.669
OPA1	O60313-1.3	E519F	Pathogenic	0.98
OPA1	O60313-1.3	E519G	Pathogenic	0.987
OPA1	O60313-1.3	E519H	Pathogenic	0.907
OPA1	O60313-1.3	E519I	Pathogenic	0.981
OPA1	O60313-1.3	E519K	Pathogenic	0.823
OPA1	O60313-1.3	E519L	Pathogenic	0.982
OPA1	O60313-1.3	E519M	Pathogenic	0.967
OPA1	O60313-1.3	E519N	Pathogenic	0.95
OPA1	O60313-1.3	E519P	Pathogenic	0.941
OPA1	O60313-1.3	E519Q	Pathogenic	0.62
OPA1	O60313-1.3	E519R	Pathogenic	0.927
OPA1	O60313-1.3	E519S	Pathogenic	0.912
OPA1	O60313-1.3	E519T	Pathogenic	0.961
OPA1	O60313-1.3	E519V	Pathogenic	0.969
OPA1	O60313-1.3	E519W	Pathogenic	0.967
OPA1	O60313-1.3	E519Y	Pathogenic	0.973
OPA1	O60313-1.3	E520A	Pathogenic	0.936
OPA1	O60313-1.3	E520C	Pathogenic	0.995
OPA1	O60313-1.3	E520D	Pathogenic	0.582
OPA1	O60313-1.3	E520F	Pathogenic	0.971
OPA1	O60313-1.3	E520G	Pathogenic	0.981
OPA1	O60313-1.3	E520H	Pathogenic	0.871
OPA1	O60313-1.3	E520I	Pathogenic	0.972
OPA1	O60313-1.3	E520K	Pathogenic	0.762
OPA1	O60313-1.3	E520L	Pathogenic	0.975
OPA1	O60313-1.3	E520M	Pathogenic	0.953
OPA1	O60313-1.3	E520N	Pathogenic	0.929
OPA1	O60313-1.3	E520P	Pathogenic	0.917
OPA1	O60313-1.3	E520Q	Pathogenic	0.529
OPA1	O60313-1.3	E520R	Pathogenic	0.897
OPA1	O60313-1.3	E520S	Pathogenic	0.877
OPA1	O60313-1.3	E520T	Pathogenic	0.944
OPA1	O60313-1.3	E520V	Pathogenic	0.955
OPA1	O60313-1.3	E520W	Pathogenic	0.952
OPA1	O60313-1.3	E520Y	Pathogenic	0.961
OPA1	O60313-1.3	E521A	Neutral	0.087
OPA1	O60313-1.3	E521C	Pathogenic	0.574
OPA1	O60313-1.3	E521D	Neutral	0.009
OPA1	O60313-1.3	E521F	Neutral	0.18
OPA1	O60313-1.3	E521G	Neutral	0.254
OPA1	O60313-1.3	E521H	Neutral	0.042
OPA1	O60313-1.3	E521I	Neutral	0.184
OPA1	O60313-1.3	E521K	Neutral	0.02
OPA1	O60313-1.3	E521L	Neutral	0.198
OPA1	O60313-1.3	E521M	Neutral	0.116
OPA1	O60313-1.3	E521N	Neutral	0.078
OPA1	O60313-1.3	E521P	Neutral	0.067
OPA1	O60313-1.3	E521Q	Neutral	0.007
OPA1	O60313-1.3	E521R	Neutral	0.053
OPA1	O60313-1.3	E521S	Neutral	0.044
OPA1	O60313-1.3	E521T	Neutral	0.099
OPA1	O60313-1.3	E521V	Neutral	0.122
OPA1	O60313-1.3	E521W	Neutral	0.115
OPA1	O60313-1.3	E521Y	Neutral	0.136
OPA1	O60313-1.3	F522A	Pathogenic	0.982
OPA1	O60313-1.3	F522C	Pathogenic	0.991
OPA1	O60313-1.3	F522D	Pathogenic	0.985
OPA1	O60313-1.3	F522E	Pathogenic	0.987
OPA1	O60313-1.3	F522G	Pathogenic	0.991
OPA1	O60313-1.3	F522H	Pathogenic	0.951
OPA1	O60313-1.3	F522I	Pathogenic	0.968
OPA1	O60313-1.3	F522K	Pathogenic	0.984
OPA1	O60313-1.3	F522L	Pathogenic	0.966
OPA1	O60313-1.3	F522M	Pathogenic	0.949
OPA1	O60313-1.3	F522N	Pathogenic	0.987
OPA1	O60313-1.3	F522P	Pathogenic	0.999
OPA1	O60313-1.3	F522Q	Pathogenic	0.991
OPA1	O60313-1.3	F522R	Pathogenic	0.983
OPA1	O60313-1.3	F522S	Pathogenic	0.976
OPA1	O60313-1.3	F522T	Pathogenic	0.983
OPA1	O60313-1.3	F522V	Pathogenic	0.98
OPA1	O60313-1.3	F522W	Pathogenic	0.868
OPA1	O60313-1.3	F522Y	Neutral	0.377
OPA1	O60313-1.3	F523A	Pathogenic	0.982
OPA1	O60313-1.3	F523C	Pathogenic	0.991
OPA1	O60313-1.3	F523D	Pathogenic	0.985
OPA1	O60313-1.3	F523E	Pathogenic	0.987
OPA1	O60313-1.3	F523G	Pathogenic	0.991
OPA1	O60313-1.3	F523H	Pathogenic	0.951
OPA1	O60313-1.3	F523I	Pathogenic	0.968
OPA1	O60313-1.3	F523K	Pathogenic	0.984
OPA1	O60313-1.3	F523L	Pathogenic	0.966
OPA1	O60313-1.3	F523M	Pathogenic	0.949
OPA1	O60313-1.3	F523N	Pathogenic	0.987
OPA1	O60313-1.3	F523P	Pathogenic	0.999
OPA1	O60313-1.3	F523Q	Pathogenic	0.991
OPA1	O60313-1.3	F523R	Pathogenic	0.983
OPA1	O60313-1.3	F523S	Pathogenic	0.976
OPA1	O60313-1.3	F523T	Pathogenic	0.983
OPA1	O60313-1.3	F523V	Pathogenic	0.98
OPA1	O60313-1.3	F523W	Pathogenic	0.868
OPA1	O60313-1.3	F523Y	Neutral	0.377
OPA1	O60313-1.3	Q524A	Neutral	0.324
OPA1	O60313-1.3	Q524C	Pathogenic	0.7
OPA1	O60313-1.3	Q524D	Neutral	0.15
OPA1	O60313-1.3	Q524E	Neutral	0.025
OPA1	O60313-1.3	Q524F	Pathogenic	0.533
OPA1	O60313-1.3	Q524G	Pathogenic	0.632
OPA1	O60313-1.3	Q524H	Neutral	0.186
OPA1	O60313-1.3	Q524I	Pathogenic	0.54
OPA1	O60313-1.3	Q524K	Neutral	0.048
OPA1	O60313-1.3	Q524L	Neutral	0.308
OPA1	O60313-1.3	Q524M	Neutral	0.075
OPA1	O60313-1.3	Q524N	Neutral	0.174
OPA1	O60313-1.3	Q524P	Neutral	0.264
OPA1	O60313-1.3	Q524R	Neutral	0.045
OPA1	O60313-1.3	Q524S	Neutral	0.188
OPA1	O60313-1.3	Q524T	Neutral	0.356
OPA1	O60313-1.3	Q524V	Neutral	0.41
OPA1	O60313-1.3	Q524W	Neutral	0.189
OPA1	O60313-1.3	Q524Y	Neutral	0.221
OPA1	O60313-1.3	N525A	Pathogenic	0.949
OPA1	O60313-1.3	N525C	Pathogenic	0.969
OPA1	O60313-1.3	N525D	Pathogenic	0.62
OPA1	O60313-1.3	N525E	Pathogenic	0.838
OPA1	O60313-1.3	N525F	Pathogenic	0.93
OPA1	O60313-1.3	N525G	Pathogenic	0.73
OPA1	O60313-1.3	N525H	Neutral	0.477
OPA1	O60313-1.3	N525I	Pathogenic	0.932
OPA1	O60313-1.3	N525K	Pathogenic	0.773
OPA1	O60313-1.3	N525L	Pathogenic	0.937
OPA1	O60313-1.3	N525M	Pathogenic	0.888
OPA1	O60313-1.3	N525P	Pathogenic	0.932
OPA1	O60313-1.3	N525Q	Pathogenic	0.788
OPA1	O60313-1.3	N525R	Pathogenic	0.762
OPA1	O60313-1.3	N525S	Pathogenic	0.515
OPA1	O60313-1.3	N525T	Pathogenic	0.717
OPA1	O60313-1.3	N525V	Pathogenic	0.962
OPA1	O60313-1.3	N525W	Pathogenic	0.958
OPA1	O60313-1.3	N525Y	Pathogenic	0.905
OPA1	O60313-1.3	S526A	Pathogenic	0.841
OPA1	O60313-1.3	S526C	Pathogenic	0.959
OPA1	O60313-1.3	S526D	Pathogenic	0.911
OPA1	O60313-1.3	S526E	Pathogenic	0.915
OPA1	O60313-1.3	S526F	Pathogenic	0.964
OPA1	O60313-1.3	S526G	Pathogenic	0.95
OPA1	O60313-1.3	S526H	Pathogenic	0.978
OPA1	O60313-1.3	S526I	Pathogenic	0.965
OPA1	O60313-1.3	S526K	Pathogenic	0.877
OPA1	O60313-1.3	S526L	Pathogenic	0.968
OPA1	O60313-1.3	S526M	Pathogenic	0.941
OPA1	O60313-1.3	S526N	Pathogenic	0.802
OPA1	O60313-1.3	S526P	Pathogenic	0.967
OPA1	O60313-1.3	S526Q	Pathogenic	0.94
OPA1	O60313-1.3	S526R	Pathogenic	0.951
OPA1	O60313-1.3	S526T	Pathogenic	0.84
OPA1	O60313-1.3	S526V	Pathogenic	0.981
OPA1	O60313-1.3	S526W	Pathogenic	0.979
OPA1	O60313-1.3	S526Y	Pathogenic	0.982
OPA1	O60313-1.3	K527A	Neutral	0.482
OPA1	O60313-1.3	K527C	Pathogenic	0.819
OPA1	O60313-1.3	K527D	Pathogenic	0.732
OPA1	O60313-1.3	K527E	Neutral	0.236
OPA1	O60313-1.3	K527F	Pathogenic	0.722
OPA1	O60313-1.3	K527G	Pathogenic	0.769
OPA1	O60313-1.3	K527H	Pathogenic	0.57
OPA1	O60313-1.3	K527I	Pathogenic	0.711
OPA1	O60313-1.3	K527L	Neutral	0.483
OPA1	O60313-1.3	K527M	Neutral	0.331
OPA1	O60313-1.3	K527N	Neutral	0.451
OPA1	O60313-1.3	K527P	Neutral	0.411
OPA1	O60313-1.3	K527Q	Neutral	0.176
OPA1	O60313-1.3	K527R	Neutral	0.132
OPA1	O60313-1.3	K527S	Neutral	0.311
OPA1	O60313-1.3	K527T	Pathogenic	0.518
OPA1	O60313-1.3	K527V	Pathogenic	0.575
OPA1	O60313-1.3	K527W	Pathogenic	0.606
OPA1	O60313-1.3	K527Y	Pathogenic	0.652
OPA1	O60313-1.3	L528A	Pathogenic	0.913
OPA1	O60313-1.3	L528C	Pathogenic	0.955
OPA1	O60313-1.3	L528D	Pathogenic	0.991
OPA1	O60313-1.3	L528E	Pathogenic	0.978
OPA1	O60313-1.3	L528F	Pathogenic	0.935
OPA1	O60313-1.3	L528G	Pathogenic	0.994
OPA1	O60313-1.3	L528H	Pathogenic	0.989
OPA1	O60313-1.3	L528I	Pathogenic	0.636
OPA1	O60313-1.3	L528K	Pathogenic	0.917
OPA1	O60313-1.3	L528M	Pathogenic	0.555
OPA1	O60313-1.3	L528N	Pathogenic	0.977
OPA1	O60313-1.3	L528P	Pathogenic	0.993
OPA1	O60313-1.3	L528Q	Pathogenic	0.957
OPA1	O60313-1.3	L528R	Pathogenic	0.912
OPA1	O60313-1.3	L528S	Pathogenic	0.958
OPA1	O60313-1.3	L528T	Pathogenic	0.917
OPA1	O60313-1.3	L528V	Pathogenic	0.769
OPA1	O60313-1.3	L528W	Pathogenic	0.986
OPA1	O60313-1.3	L528Y	Pathogenic	0.957
OPA1	O60313-1.3	L529A	Neutral	0.224
OPA1	O60313-1.3	L529C	Neutral	0.365
OPA1	O60313-1.3	L529D	Pathogenic	0.741
OPA1	O60313-1.3	L529E	Pathogenic	0.544
OPA1	O60313-1.3	L529F	Neutral	0.281
OPA1	O60313-1.3	L529G	Pathogenic	0.832
OPA1	O60313-1.3	L529H	Pathogenic	0.714
OPA1	O60313-1.3	L529I	Neutral	0.046
OPA1	O60313-1.3	L529K	Neutral	0.232
OPA1	O60313-1.3	L529M	Neutral	0.033
OPA1	O60313-1.3	L529N	Pathogenic	0.54
OPA1	O60313-1.3	L529P	Pathogenic	0.794
OPA1	O60313-1.3	L529Q	Neutral	0.381
OPA1	O60313-1.3	L529R	Neutral	0.222
OPA1	O60313-1.3	L529S	Neutral	0.384
OPA1	O60313-1.3	L529T	Neutral	0.233
OPA1	O60313-1.3	L529V	Neutral	0.083
OPA1	O60313-1.3	L529W	Pathogenic	0.659
OPA1	O60313-1.3	L529Y	Neutral	0.378
OPA1	O60313-1.3	K530A	Pathogenic	0.569
OPA1	O60313-1.3	K530C	Pathogenic	0.865
OPA1	O60313-1.3	K530D	Pathogenic	0.795
OPA1	O60313-1.3	K530E	Neutral	0.304
OPA1	O60313-1.3	K530F	Pathogenic	0.787
OPA1	O60313-1.3	K530G	Pathogenic	0.825
OPA1	O60313-1.3	K530H	Pathogenic	0.652
OPA1	O60313-1.3	K530I	Pathogenic	0.777
OPA1	O60313-1.3	K530L	Pathogenic	0.569
OPA1	O60313-1.3	K530M	Neutral	0.412
OPA1	O60313-1.3	K530N	Pathogenic	0.538
OPA1	O60313-1.3	K530P	Neutral	0.497
OPA1	O60313-1.3	K530Q	Neutral	0.233
OPA1	O60313-1.3	K530R	Neutral	0.177
OPA1	O60313-1.3	K530S	Neutral	0.389
OPA1	O60313-1.3	K530T	Pathogenic	0.604
OPA1	O60313-1.3	K530V	Pathogenic	0.657
OPA1	O60313-1.3	K530W	Pathogenic	0.685
OPA1	O60313-1.3	K530Y	Pathogenic	0.726
OPA1	O60313-1.3	T531A	Neutral	0.19
OPA1	O60313-1.3	T531C	Neutral	0.282
OPA1	O60313-1.3	T531D	Neutral	0.233
OPA1	O60313-1.3	T531E	Neutral	0.245
OPA1	O60313-1.3	T531F	Neutral	0.323
OPA1	O60313-1.3	T531G	Pathogenic	0.603
OPA1	O60313-1.3	T531H	Pathogenic	0.648
OPA1	O60313-1.3	T531I	Neutral	0.145
OPA1	O60313-1.3	T531K	Neutral	0.176
OPA1	O60313-1.3	T531L	Neutral	0.157
OPA1	O60313-1.3	T531M	Neutral	0.222
OPA1	O60313-1.3	T531N	Neutral	0.109
OPA1	O60313-1.3	T531P	Neutral	0.337
OPA1	O60313-1.3	T531Q	Neutral	0.319
OPA1	O60313-1.3	T531R	Neutral	0.167
OPA1	O60313-1.3	T531S	Neutral	0.062
OPA1	O60313-1.3	T531V	Neutral	0.097
OPA1	O60313-1.3	T531W	Neutral	0.22
OPA1	O60313-1.3	T531Y	Neutral	0.499
OPA1	O60313-1.3	S532A	Neutral	0.061
OPA1	O60313-1.3	S532C	Neutral	0.223
OPA1	O60313-1.3	S532D	Neutral	0.112
OPA1	O60313-1.3	S532E	Neutral	0.117
OPA1	O60313-1.3	S532F	Neutral	0.249
OPA1	O60313-1.3	S532G	Neutral	0.188
OPA1	O60313-1.3	S532H	Neutral	0.356
OPA1	O60313-1.3	S532I	Neutral	0.254
OPA1	O60313-1.3	S532K	Neutral	0.08
OPA1	O60313-1.3	S532L	Neutral	0.272
OPA1	O60313-1.3	S532M	Neutral	0.165
OPA1	O60313-1.3	S532N	Neutral	0.047
OPA1	O60313-1.3	S532P	Neutral	0.264
OPA1	O60313-1.3	S532Q	Neutral	0.161
OPA1	O60313-1.3	S532R	Neutral	0.192
OPA1	O60313-1.3	S532T	Neutral	0.061
OPA1	O60313-1.3	S532V	Neutral	0.384
OPA1	O60313-1.3	S532W	Neutral	0.361
OPA1	O60313-1.3	S532Y	Neutral	0.408
OPA1	O60313-1.3	M533A	Pathogenic	0.592
OPA1	O60313-1.3	M533C	Pathogenic	0.743
OPA1	O60313-1.3	M533D	Pathogenic	0.832
OPA1	O60313-1.3	M533E	Pathogenic	0.674
OPA1	O60313-1.3	M533F	Neutral	0.454
OPA1	O60313-1.3	M533G	Pathogenic	0.895
OPA1	O60313-1.3	M533H	Pathogenic	0.812
OPA1	O60313-1.3	M533I	Neutral	0.227
OPA1	O60313-1.3	M533K	Neutral	0.344
OPA1	O60313-1.3	M533L	Neutral	0.1
OPA1	O60313-1.3	M533N	Pathogenic	0.671
OPA1	O60313-1.3	M533P	Pathogenic	0.87
OPA1	O60313-1.3	M533Q	Neutral	0.269
OPA1	O60313-1.3	M533R	Neutral	0.33
OPA1	O60313-1.3	M533S	Pathogenic	0.519
OPA1	O60313-1.3	M533T	Pathogenic	0.604
OPA1	O60313-1.3	M533V	Neutral	0.313
OPA1	O60313-1.3	M533W	Pathogenic	0.587
OPA1	O60313-1.3	M533Y	Pathogenic	0.754
OPA1	O60313-1.3	L534A	Pathogenic	0.605
OPA1	O60313-1.3	L534C	Pathogenic	0.753
OPA1	O60313-1.3	L534D	Pathogenic	0.938
OPA1	O60313-1.3	L534E	Pathogenic	0.864
OPA1	O60313-1.3	L534F	Pathogenic	0.675
OPA1	O60313-1.3	L534G	Pathogenic	0.963
OPA1	O60313-1.3	L534H	Pathogenic	0.93
OPA1	O60313-1.3	L534I	Neutral	0.202
OPA1	O60313-1.3	L534K	Pathogenic	0.617
OPA1	O60313-1.3	L534M	Neutral	0.154
OPA1	O60313-1.3	L534N	Pathogenic	0.862
OPA1	O60313-1.3	L534P	Pathogenic	0.953
OPA1	O60313-1.3	L534Q	Pathogenic	0.766
OPA1	O60313-1.3	L534R	Pathogenic	0.602
OPA1	O60313-1.3	L534S	Pathogenic	0.768
OPA1	O60313-1.3	L534T	Pathogenic	0.617
OPA1	O60313-1.3	L534V	Neutral	0.326
OPA1	O60313-1.3	L534W	Pathogenic	0.911
OPA1	O60313-1.3	L534Y	Pathogenic	0.764
OPA1	O60313-1.3	K535A	Pathogenic	0.682
OPA1	O60313-1.3	K535C	Pathogenic	0.913
OPA1	O60313-1.3	K535D	Pathogenic	0.863
OPA1	O60313-1.3	K535E	Neutral	0.415
OPA1	O60313-1.3	K535F	Pathogenic	0.857
OPA1	O60313-1.3	K535G	Pathogenic	0.885
OPA1	O60313-1.3	K535H	Pathogenic	0.753
OPA1	O60313-1.3	K535I	Pathogenic	0.85
OPA1	O60313-1.3	K535L	Pathogenic	0.683
OPA1	O60313-1.3	K535M	Pathogenic	0.533
OPA1	O60313-1.3	K535N	Pathogenic	0.655
OPA1	O60313-1.3	K535P	Pathogenic	0.617
OPA1	O60313-1.3	K535Q	Neutral	0.331
OPA1	O60313-1.3	K535R	Neutral	0.259
OPA1	O60313-1.3	K535S	Pathogenic	0.51
OPA1	O60313-1.3	K535T	Pathogenic	0.713
OPA1	O60313-1.3	K535V	Pathogenic	0.758
OPA1	O60313-1.3	K535W	Pathogenic	0.78
OPA1	O60313-1.3	K535Y	Pathogenic	0.812
OPA1	O60313-1.3	A536C	Neutral	0.324
OPA1	O60313-1.3	A536D	Pathogenic	0.732
OPA1	O60313-1.3	A536E	Neutral	0.498
OPA1	O60313-1.3	A536F	Pathogenic	0.615
OPA1	O60313-1.3	A536G	Neutral	0.401
OPA1	O60313-1.3	A536H	Pathogenic	0.849
OPA1	O60313-1.3	A536I	Neutral	0.362
OPA1	O60313-1.3	A536K	Neutral	0.395
OPA1	O60313-1.3	A536L	Neutral	0.384
OPA1	O60313-1.3	A536M	Neutral	0.489
OPA1	O60313-1.3	A536N	Pathogenic	0.758
OPA1	O60313-1.3	A536P	Pathogenic	0.635
OPA1	O60313-1.3	A536Q	Pathogenic	0.588
OPA1	O60313-1.3	A536R	Neutral	0.38
OPA1	O60313-1.3	A536S	Neutral	0.19
OPA1	O60313-1.3	A536T	Neutral	0.452
OPA1	O60313-1.3	A536V	Neutral	0.264
OPA1	O60313-1.3	A536W	Pathogenic	0.732
OPA1	O60313-1.3	A536Y	Pathogenic	0.77
OPA1	O60313-1.3	H537A	Pathogenic	0.977
OPA1	O60313-1.3	H537C	Pathogenic	0.986
OPA1	O60313-1.3	H537D	Pathogenic	0.893
OPA1	O60313-1.3	H537E	Pathogenic	0.776
OPA1	O60313-1.3	H537F	Pathogenic	0.813
OPA1	O60313-1.3	H537G	Pathogenic	0.977
OPA1	O60313-1.3	H537I	Pathogenic	0.974
OPA1	O60313-1.3	H537K	Pathogenic	0.876
OPA1	O60313-1.3	H537L	Pathogenic	0.976
OPA1	O60313-1.3	H537M	Pathogenic	0.956
OPA1	O60313-1.3	H537N	Pathogenic	0.541
OPA1	O60313-1.3	H537P	Pathogenic	0.97
OPA1	O60313-1.3	H537Q	Pathogenic	0.838
OPA1	O60313-1.3	H537R	Pathogenic	0.697
OPA1	O60313-1.3	H537S	Pathogenic	0.938
OPA1	O60313-1.3	H537T	Pathogenic	0.98
OPA1	O60313-1.3	H537V	Pathogenic	0.984
OPA1	O60313-1.3	H537W	Pathogenic	0.881
OPA1	O60313-1.3	H537Y	Neutral	0.271
OPA1	O60313-1.3	Q538A	Pathogenic	0.992
OPA1	O60313-1.3	Q538C	Pathogenic	0.998
OPA1	O60313-1.3	Q538D	Pathogenic	0.978
OPA1	O60313-1.3	Q538E	Pathogenic	0.863
OPA1	O60313-1.3	Q538F	Pathogenic	0.996
OPA1	O60313-1.3	Q538G	Pathogenic	0.998
OPA1	O60313-1.3	Q538H	Pathogenic	0.983
OPA1	O60313-1.3	Q538I	Pathogenic	0.997
OPA1	O60313-1.3	Q538K	Pathogenic	0.926
OPA1	O60313-1.3	Q538L	Pathogenic	0.991
OPA1	O60313-1.3	Q538M	Pathogenic	0.953
OPA1	O60313-1.3	Q538N	Pathogenic	0.981
OPA1	O60313-1.3	Q538P	Pathogenic	0.989
OPA1	O60313-1.3	Q538R	Pathogenic	0.921
OPA1	O60313-1.3	Q538S	Pathogenic	0.983
OPA1	O60313-1.3	Q538T	Pathogenic	0.993
OPA1	O60313-1.3	Q538V	Pathogenic	0.994
OPA1	O60313-1.3	Q538W	Pathogenic	0.983
OPA1	O60313-1.3	Q538Y	Pathogenic	0.986
OPA1	O60313-1.3	V539A	Pathogenic	0.928
OPA1	O60313-1.3	V539C	Pathogenic	0.987
OPA1	O60313-1.3	V539D	Pathogenic	0.992
OPA1	O60313-1.3	V539E	Pathogenic	0.981
OPA1	O60313-1.3	V539F	Pathogenic	0.981
OPA1	O60313-1.3	V539G	Pathogenic	0.996
OPA1	O60313-1.3	V539H	Pathogenic	0.997
OPA1	O60313-1.3	V539I	Neutral	0.434
OPA1	O60313-1.3	V539K	Pathogenic	0.972
OPA1	O60313-1.3	V539L	Pathogenic	0.876
OPA1	O60313-1.3	V539M	Pathogenic	0.916
OPA1	O60313-1.3	V539N	Pathogenic	0.994
OPA1	O60313-1.3	V539P	Pathogenic	0.994
OPA1	O60313-1.3	V539Q	Pathogenic	0.987
OPA1	O60313-1.3	V539R	Pathogenic	0.989
OPA1	O60313-1.3	V539S	Pathogenic	0.988
OPA1	O60313-1.3	V539T	Pathogenic	0.932
OPA1	O60313-1.3	V539W	Pathogenic	0.996
OPA1	O60313-1.3	V539Y	Pathogenic	0.986
OPA1	O60313-1.3	T540A	Pathogenic	0.986
OPA1	O60313-1.3	T540C	Pathogenic	0.991
OPA1	O60313-1.3	T540D	Pathogenic	0.989
OPA1	O60313-1.3	T540E	Pathogenic	0.99
OPA1	O60313-1.3	T540F	Pathogenic	0.993
OPA1	O60313-1.3	T540G	Pathogenic	0.998
OPA1	O60313-1.3	T540H	Pathogenic	0.998
OPA1	O60313-1.3	T540I	Pathogenic	0.98
OPA1	O60313-1.3	T540K	Pathogenic	0.984
OPA1	O60313-1.3	T540L	Pathogenic	0.982
OPA1	O60313-1.3	T540M	Pathogenic	0.988
OPA1	O60313-1.3	T540N	Pathogenic	0.973
OPA1	O60313-1.3	T540P	Pathogenic	0.993
OPA1	O60313-1.3	T540Q	Pathogenic	0.993
OPA1	O60313-1.3	T540R	Pathogenic	0.983
OPA1	O60313-1.3	T540S	Pathogenic	0.951
OPA1	O60313-1.3	T540V	Pathogenic	0.969
OPA1	O60313-1.3	T540W	Pathogenic	0.988
OPA1	O60313-1.3	T540Y	Pathogenic	0.997
OPA1	O60313-1.3	T541A	Pathogenic	0.966
OPA1	O60313-1.3	T541C	Pathogenic	0.98
OPA1	O60313-1.3	T541D	Pathogenic	0.974
OPA1	O60313-1.3	T541E	Pathogenic	0.975
OPA1	O60313-1.3	T541F	Pathogenic	0.983
OPA1	O60313-1.3	T541G	Pathogenic	0.995
OPA1	O60313-1.3	T541H	Pathogenic	0.996
OPA1	O60313-1.3	T541I	Pathogenic	0.954
OPA1	O60313-1.3	T541K	Pathogenic	0.963
OPA1	O60313-1.3	T541L	Pathogenic	0.958
OPA1	O60313-1.3	T541M	Pathogenic	0.972
OPA1	O60313-1.3	T541N	Pathogenic	0.937
OPA1	O60313-1.3	T541P	Pathogenic	0.984
OPA1	O60313-1.3	T541Q	Pathogenic	0.983
OPA1	O60313-1.3	T541R	Pathogenic	0.961
OPA1	O60313-1.3	T541S	Pathogenic	0.89
OPA1	O60313-1.3	T541V	Pathogenic	0.929
OPA1	O60313-1.3	T541W	Pathogenic	0.972
OPA1	O60313-1.3	T541Y	Pathogenic	0.992
OPA1	O60313-1.3	R542A	Neutral	0.323
OPA1	O60313-1.3	R542C	Pathogenic	0.699
OPA1	O60313-1.3	R542D	Pathogenic	0.802
OPA1	O60313-1.3	R542E	Neutral	0.314
OPA1	O60313-1.3	R542F	Pathogenic	0.571
OPA1	O60313-1.3	R542G	Pathogenic	0.63
OPA1	O60313-1.3	R542H	Neutral	0.189
OPA1	O60313-1.3	R542I	Pathogenic	0.558
OPA1	O60313-1.3	R542K	Neutral	0.076
OPA1	O60313-1.3	R542L	Neutral	0.323
OPA1	O60313-1.3	R542M	Neutral	0.202
OPA1	O60313-1.3	R542N	Neutral	0.296
OPA1	O60313-1.3	R542P	Pathogenic	0.508
OPA1	O60313-1.3	R542Q	Neutral	0.099
OPA1	O60313-1.3	R542S	Neutral	0.401
OPA1	O60313-1.3	R542T	Neutral	0.355
OPA1	O60313-1.3	R542V	Pathogenic	0.668
OPA1	O60313-1.3	R542W	Neutral	0.464
OPA1	O60313-1.3	R542Y	Pathogenic	0.501
OPA1	O60313-1.3	N543A	Pathogenic	0.993
OPA1	O60313-1.3	N543C	Pathogenic	0.996
OPA1	O60313-1.3	N543D	Pathogenic	0.924
OPA1	O60313-1.3	N543E	Pathogenic	0.975
OPA1	O60313-1.3	N543F	Pathogenic	0.99
OPA1	O60313-1.3	N543G	Pathogenic	0.953
OPA1	O60313-1.3	N543H	Pathogenic	0.872
OPA1	O60313-1.3	N543I	Pathogenic	0.99
OPA1	O60313-1.3	N543K	Pathogenic	0.962
OPA1	O60313-1.3	N543L	Pathogenic	0.991
OPA1	O60313-1.3	N543M	Pathogenic	0.983
OPA1	O60313-1.3	N543P	Pathogenic	0.99
OPA1	O60313-1.3	N543Q	Pathogenic	0.965
OPA1	O60313-1.3	N543R	Pathogenic	0.96
OPA1	O60313-1.3	N543S	Pathogenic	0.888
OPA1	O60313-1.3	N543T	Pathogenic	0.95
OPA1	O60313-1.3	N543V	Pathogenic	0.995
OPA1	O60313-1.3	N543W	Pathogenic	0.994
OPA1	O60313-1.3	N543Y	Pathogenic	0.986
OPA1	O60313-1.3	L544A	Pathogenic	0.975
OPA1	O60313-1.3	L544C	Pathogenic	0.987
OPA1	O60313-1.3	L544D	Pathogenic	0.997
OPA1	O60313-1.3	L544E	Pathogenic	0.994
OPA1	O60313-1.3	L544F	Pathogenic	0.981
OPA1	O60313-1.3	L544G	Pathogenic	0.998
OPA1	O60313-1.3	L544H	Pathogenic	0.997
OPA1	O60313-1.3	L544I	Pathogenic	0.865
OPA1	O60313-1.3	L544K	Pathogenic	0.976
OPA1	O60313-1.3	L544M	Pathogenic	0.821
OPA1	O60313-1.3	L544N	Pathogenic	0.994
OPA1	O60313-1.3	L544P	Pathogenic	0.998
OPA1	O60313-1.3	L544Q	Pathogenic	0.988
OPA1	O60313-1.3	L544R	Pathogenic	0.975
OPA1	O60313-1.3	L544S	Pathogenic	0.988
OPA1	O60313-1.3	L544T	Pathogenic	0.976
OPA1	O60313-1.3	L544V	Pathogenic	0.924
OPA1	O60313-1.3	L544W	Pathogenic	0.996
OPA1	O60313-1.3	L544Y	Pathogenic	0.988
OPA1	O60313-1.3	S545A	Pathogenic	0.946
OPA1	O60313-1.3	S545C	Pathogenic	0.987
OPA1	O60313-1.3	S545D	Pathogenic	0.972
OPA1	O60313-1.3	S545E	Pathogenic	0.973
OPA1	O60313-1.3	S545F	Pathogenic	0.989
OPA1	O60313-1.3	S545G	Pathogenic	0.984
OPA1	O60313-1.3	S545H	Pathogenic	0.993
OPA1	O60313-1.3	S545I	Pathogenic	0.989
OPA1	O60313-1.3	S545K	Pathogenic	0.96
OPA1	O60313-1.3	S545L	Pathogenic	0.99
OPA1	O60313-1.3	S545M	Pathogenic	0.982
OPA1	O60313-1.3	S545N	Pathogenic	0.931
OPA1	O60313-1.3	S545P	Pathogenic	0.99
OPA1	O60313-1.3	S545Q	Pathogenic	0.981
OPA1	O60313-1.3	S545R	Pathogenic	0.985
OPA1	O60313-1.3	S545T	Pathogenic	0.946
OPA1	O60313-1.3	S545V	Pathogenic	0.994
OPA1	O60313-1.3	S545W	Pathogenic	0.994
OPA1	O60313-1.3	S545Y	Pathogenic	0.995
OPA1	O60313-1.3	L546A	Pathogenic	0.948
OPA1	O60313-1.3	L546C	Pathogenic	0.973
OPA1	O60313-1.3	L546D	Pathogenic	0.995
OPA1	O60313-1.3	L546E	Pathogenic	0.987
OPA1	O60313-1.3	L546F	Pathogenic	0.961
OPA1	O60313-1.3	L546G	Pathogenic	0.997
OPA1	O60313-1.3	L546H	Pathogenic	0.994
OPA1	O60313-1.3	L546I	Pathogenic	0.753
OPA1	O60313-1.3	L546K	Pathogenic	0.951
OPA1	O60313-1.3	L546M	Pathogenic	0.685
OPA1	O60313-1.3	L546N	Pathogenic	0.987
OPA1	O60313-1.3	L546P	Pathogenic	0.996
OPA1	O60313-1.3	L546Q	Pathogenic	0.975
OPA1	O60313-1.3	L546R	Pathogenic	0.948
OPA1	O60313-1.3	L546S	Pathogenic	0.975
OPA1	O60313-1.3	L546T	Pathogenic	0.951
OPA1	O60313-1.3	L546V	Pathogenic	0.853
OPA1	O60313-1.3	L546W	Pathogenic	0.992
OPA1	O60313-1.3	L546Y	Pathogenic	0.975
OPA1	O60313-1.3	A547C	Pathogenic	0.974
OPA1	O60313-1.3	A547D	Pathogenic	0.995
OPA1	O60313-1.3	A547E	Pathogenic	0.988
OPA1	O60313-1.3	A547F	Pathogenic	0.992
OPA1	O60313-1.3	A547G	Pathogenic	0.982
OPA1	O60313-1.3	A547H	Pathogenic	0.998
OPA1	O60313-1.3	A547I	Pathogenic	0.978
OPA1	O60313-1.3	A547K	Pathogenic	0.981
OPA1	O60313-1.3	A547L	Pathogenic	0.98
OPA1	O60313-1.3	A547M	Pathogenic	0.987
OPA1	O60313-1.3	A547N	Pathogenic	0.996
OPA1	O60313-1.3	A547P	Pathogenic	0.993
OPA1	O60313-1.3	A547Q	Pathogenic	0.991
OPA1	O60313-1.3	A547R	Pathogenic	0.98
OPA1	O60313-1.3	A547S	Pathogenic	0.949
OPA1	O60313-1.3	A547T	Pathogenic	0.985
OPA1	O60313-1.3	A547V	Pathogenic	0.966
OPA1	O60313-1.3	A547W	Pathogenic	0.995
OPA1	O60313-1.3	A547Y	Pathogenic	0.996
OPA1	O60313-1.3	V548A	Pathogenic	0.965
OPA1	O60313-1.3	V548C	Pathogenic	0.994
OPA1	O60313-1.3	V548D	Pathogenic	0.996
OPA1	O60313-1.3	V548E	Pathogenic	0.991
OPA1	O60313-1.3	V548F	Pathogenic	0.991
OPA1	O60313-1.3	V548G	Pathogenic	0.998
OPA1	O60313-1.3	V548H	Pathogenic	0.998
OPA1	O60313-1.3	V548I	Pathogenic	0.618
OPA1	O60313-1.3	V548K	Pathogenic	0.986
OPA1	O60313-1.3	V548L	Pathogenic	0.937
OPA1	O60313-1.3	V548M	Pathogenic	0.958
OPA1	O60313-1.3	V548N	Pathogenic	0.997
OPA1	O60313-1.3	V548P	Pathogenic	0.997
OPA1	O60313-1.3	V548Q	Pathogenic	0.994
OPA1	O60313-1.3	V548R	Pathogenic	0.995
OPA1	O60313-1.3	V548S	Pathogenic	0.994
OPA1	O60313-1.3	V548T	Pathogenic	0.966
OPA1	O60313-1.3	V548W	Pathogenic	0.998
OPA1	O60313-1.3	V548Y	Pathogenic	0.993
OPA1	O60313-1.3	S549A	Pathogenic	0.628
OPA1	O60313-1.3	S549C	Pathogenic	0.882
OPA1	O60313-1.3	S549D	Pathogenic	0.767
OPA1	O60313-1.3	S549E	Pathogenic	0.776
OPA1	O60313-1.3	S549F	Pathogenic	0.896
OPA1	O60313-1.3	S549G	Pathogenic	0.858
OPA1	O60313-1.3	S549H	Pathogenic	0.935
OPA1	O60313-1.3	S549I	Pathogenic	0.899
OPA1	O60313-1.3	S549K	Pathogenic	0.695
OPA1	O60313-1.3	S549L	Pathogenic	0.907
OPA1	O60313-1.3	S549M	Pathogenic	0.838
OPA1	O60313-1.3	S549N	Pathogenic	0.565
OPA1	O60313-1.3	S549P	Pathogenic	0.904
OPA1	O60313-1.3	S549Q	Pathogenic	0.833
OPA1	O60313-1.3	S549R	Pathogenic	0.861
OPA1	O60313-1.3	S549T	Pathogenic	0.627
OPA1	O60313-1.3	S549V	Pathogenic	0.942
OPA1	O60313-1.3	S549W	Pathogenic	0.936
OPA1	O60313-1.3	S549Y	Pathogenic	0.947
OPA1	O60313-1.3	D550A	Pathogenic	0.964
OPA1	O60313-1.3	D550C	Pathogenic	0.978
OPA1	O60313-1.3	D550E	Neutral	0.482
OPA1	O60313-1.3	D550F	Pathogenic	0.949
OPA1	O60313-1.3	D550G	Pathogenic	0.92
OPA1	O60313-1.3	D550H	Pathogenic	0.916
OPA1	O60313-1.3	D550I	Pathogenic	0.951
OPA1	O60313-1.3	D550K	Pathogenic	0.95
OPA1	O60313-1.3	D550L	Pathogenic	0.984
OPA1	O60313-1.3	D550M	Pathogenic	0.97
OPA1	O60313-1.3	D550N	Pathogenic	0.733
OPA1	O60313-1.3	D550P	Pathogenic	0.875
OPA1	O60313-1.3	D550Q	Pathogenic	0.84
OPA1	O60313-1.3	D550R	Pathogenic	0.981
OPA1	O60313-1.3	D550S	Pathogenic	0.819
OPA1	O60313-1.3	D550T	Pathogenic	0.914
OPA1	O60313-1.3	D550V	Pathogenic	0.973
OPA1	O60313-1.3	D550W	Pathogenic	0.97
OPA1	O60313-1.3	D550Y	Pathogenic	0.975
OPA1	O60313-1.3	C551A	Pathogenic	0.971
OPA1	O60313-1.3	C551D	Pathogenic	0.997
OPA1	O60313-1.3	C551E	Pathogenic	0.999
OPA1	O60313-1.3	C551F	Pathogenic	0.995
OPA1	O60313-1.3	C551G	Pathogenic	0.998
OPA1	O60313-1.3	C551H	Pathogenic	0.998
OPA1	O60313-1.3	C551I	Pathogenic	0.987
OPA1	O60313-1.3	C551K	Pathogenic	0.995
OPA1	O60313-1.3	C551L	Pathogenic	0.988
OPA1	O60313-1.3	C551M	Pathogenic	0.992
OPA1	O60313-1.3	C551N	Pathogenic	0.997
OPA1	O60313-1.3	C551P	Pathogenic	0.999
OPA1	O60313-1.3	C551Q	Pathogenic	0.998
OPA1	O60313-1.3	C551R	Pathogenic	0.995
OPA1	O60313-1.3	C551S	Pathogenic	0.986
OPA1	O60313-1.3	C551T	Pathogenic	0.99
OPA1	O60313-1.3	C551V	Pathogenic	0.993
OPA1	O60313-1.3	C551W	Pathogenic	0.992
OPA1	O60313-1.3	C551Y	Pathogenic	0.998
OPA1	O60313-1.3	F552A	Pathogenic	0.994
OPA1	O60313-1.3	F552C	Pathogenic	0.997
OPA1	O60313-1.3	F552D	Pathogenic	0.995
OPA1	O60313-1.3	F552E	Pathogenic	0.996
OPA1	O60313-1.3	F552G	Pathogenic	0.997
OPA1	O60313-1.3	F552H	Pathogenic	0.983
OPA1	O60313-1.3	F552I	Pathogenic	0.989
OPA1	O60313-1.3	F552K	Pathogenic	0.994
OPA1	O60313-1.3	F552L	Pathogenic	0.988
OPA1	O60313-1.3	F552M	Pathogenic	0.982
OPA1	O60313-1.3	F552N	Pathogenic	0.996
OPA1	O60313-1.3	F552P	Pathogenic	1.0
OPA1	O60313-1.3	F552Q	Pathogenic	0.997
OPA1	O60313-1.3	F552R	Pathogenic	0.994
OPA1	O60313-1.3	F552S	Pathogenic	0.992
OPA1	O60313-1.3	F552T	Pathogenic	0.994
OPA1	O60313-1.3	F552V	Pathogenic	0.993
OPA1	O60313-1.3	F552W	Pathogenic	0.95
OPA1	O60313-1.3	F552Y	Pathogenic	0.639
OPA1	O60313-1.3	W553A	Pathogenic	0.997
OPA1	O60313-1.3	W553C	Pathogenic	0.996
OPA1	O60313-1.3	W553D	Pathogenic	0.998
OPA1	O60313-1.3	W553E	Pathogenic	0.994
OPA1	O60313-1.3	W553F	Pathogenic	0.961
OPA1	O60313-1.3	W553G	Pathogenic	0.988
OPA1	O60313-1.3	W553H	Pathogenic	0.992
OPA1	O60313-1.3	W553I	Pathogenic	0.999
OPA1	O60313-1.3	W553K	Pathogenic	0.993
OPA1	O60313-1.3	W553L	Pathogenic	0.998
OPA1	O60313-1.3	W553M	Pathogenic	0.992
OPA1	O60313-1.3	W553N	Pathogenic	0.998
OPA1	O60313-1.3	W553P	Pathogenic	0.999
OPA1	O60313-1.3	W553Q	Pathogenic	0.989
OPA1	O60313-1.3	W553R	Pathogenic	0.993
OPA1	O60313-1.3	W553S	Pathogenic	0.996
OPA1	O60313-1.3	W553T	Pathogenic	0.992
OPA1	O60313-1.3	W553V	Pathogenic	0.999
OPA1	O60313-1.3	W553Y	Pathogenic	0.804
OPA1	O60313-1.3	K554A	Pathogenic	0.976
OPA1	O60313-1.3	K554C	Pathogenic	0.995
OPA1	O60313-1.3	K554D	Pathogenic	0.992
OPA1	O60313-1.3	K554E	Pathogenic	0.931
OPA1	O60313-1.3	K554F	Pathogenic	0.991
OPA1	O60313-1.3	K554G	Pathogenic	0.993
OPA1	O60313-1.3	K554H	Pathogenic	0.983
OPA1	O60313-1.3	K554I	Pathogenic	0.991
OPA1	O60313-1.3	K554L	Pathogenic	0.976
OPA1	O60313-1.3	K554M	Pathogenic	0.956
OPA1	O60313-1.3	K554N	Pathogenic	0.973
OPA1	O60313-1.3	K554P	Pathogenic	0.968
OPA1	O60313-1.3	K554Q	Pathogenic	0.904
OPA1	O60313-1.3	K554R	Pathogenic	0.87
OPA1	O60313-1.3	K554S	Pathogenic	0.952
OPA1	O60313-1.3	K554T	Pathogenic	0.979
OPA1	O60313-1.3	K554V	Pathogenic	0.983
OPA1	O60313-1.3	K554W	Pathogenic	0.985
OPA1	O60313-1.3	K554Y	Pathogenic	0.988
OPA1	O60313-1.3	M555A	Pathogenic	0.991
OPA1	O60313-1.3	M555C	Pathogenic	0.996
OPA1	O60313-1.3	M555D	Pathogenic	0.997
OPA1	O60313-1.3	M555E	Pathogenic	0.994
OPA1	O60313-1.3	M555F	Pathogenic	0.985
OPA1	O60313-1.3	M555G	Pathogenic	0.998
OPA1	O60313-1.3	M555H	Pathogenic	0.997
OPA1	O60313-1.3	M555I	Pathogenic	0.958
OPA1	O60313-1.3	M555K	Pathogenic	0.976
OPA1	O60313-1.3	M555L	Pathogenic	0.896
OPA1	O60313-1.3	M555N	Pathogenic	0.994
OPA1	O60313-1.3	M555P	Pathogenic	0.998
OPA1	O60313-1.3	M555Q	Pathogenic	0.966
OPA1	O60313-1.3	M555R	Pathogenic	0.974
OPA1	O60313-1.3	M555S	Pathogenic	0.988
OPA1	O60313-1.3	M555T	Pathogenic	0.992
OPA1	O60313-1.3	M555V	Pathogenic	0.972
OPA1	O60313-1.3	M555W	Pathogenic	0.991
OPA1	O60313-1.3	M555Y	Pathogenic	0.996
OPA1	O60313-1.3	V556A	Pathogenic	0.965
OPA1	O60313-1.3	V556C	Pathogenic	0.994
OPA1	O60313-1.3	V556D	Pathogenic	0.996
OPA1	O60313-1.3	V556E	Pathogenic	0.991
OPA1	O60313-1.3	V556F	Pathogenic	0.991
OPA1	O60313-1.3	V556G	Pathogenic	0.998
OPA1	O60313-1.3	V556H	Pathogenic	0.998
OPA1	O60313-1.3	V556I	Pathogenic	0.618
OPA1	O60313-1.3	V556K	Pathogenic	0.986
OPA1	O60313-1.3	V556L	Pathogenic	0.937
OPA1	O60313-1.3	V556M	Pathogenic	0.958
OPA1	O60313-1.3	V556N	Pathogenic	0.997
OPA1	O60313-1.3	V556P	Pathogenic	0.997
OPA1	O60313-1.3	V556Q	Pathogenic	0.994
OPA1	O60313-1.3	V556R	Pathogenic	0.995
OPA1	O60313-1.3	V556S	Pathogenic	0.994
OPA1	O60313-1.3	V556T	Pathogenic	0.966
OPA1	O60313-1.3	V556W	Pathogenic	0.998
OPA1	O60313-1.3	V556Y	Pathogenic	0.993
OPA1	O60313-1.3	R557A	Pathogenic	0.978
OPA1	O60313-1.3	R557C	Pathogenic	0.995
OPA1	O60313-1.3	R557D	Pathogenic	0.997
OPA1	O60313-1.3	R557E	Pathogenic	0.977
OPA1	O60313-1.3	R557F	Pathogenic	0.992
OPA1	O60313-1.3	R557G	Pathogenic	0.994
OPA1	O60313-1.3	R557H	Pathogenic	0.956
OPA1	O60313-1.3	R557I	Pathogenic	0.992
OPA1	O60313-1.3	R557K	Pathogenic	0.885
OPA1	O60313-1.3	R557L	Pathogenic	0.978
OPA1	O60313-1.3	R557M	Pathogenic	0.959
OPA1	O60313-1.3	R557N	Pathogenic	0.975
OPA1	O60313-1.3	R557P	Pathogenic	0.99
OPA1	O60313-1.3	R557Q	Pathogenic	0.911
OPA1	O60313-1.3	R557S	Pathogenic	0.984
OPA1	O60313-1.3	R557T	Pathogenic	0.981
OPA1	O60313-1.3	R557V	Pathogenic	0.995
OPA1	O60313-1.3	R557W	Pathogenic	0.988
OPA1	O60313-1.3	R557Y	Pathogenic	0.989
OPA1	O60313-1.3	E558A	Pathogenic	0.985
OPA1	O60313-1.3	E558C	Pathogenic	0.999
OPA1	O60313-1.3	E558D	Pathogenic	0.857
OPA1	O60313-1.3	E558F	Pathogenic	0.993
OPA1	O60313-1.3	E558G	Pathogenic	0.996
OPA1	O60313-1.3	E558H	Pathogenic	0.967
OPA1	O60313-1.3	E558I	Pathogenic	0.993
OPA1	O60313-1.3	E558K	Pathogenic	0.933
OPA1	O60313-1.3	E558L	Pathogenic	0.994
OPA1	O60313-1.3	E558M	Pathogenic	0.989
OPA1	O60313-1.3	E558N	Pathogenic	0.982
OPA1	O60313-1.3	E558P	Pathogenic	0.979
OPA1	O60313-1.3	E558Q	Pathogenic	0.829
OPA1	O60313-1.3	E558R	Pathogenic	0.974
OPA1	O60313-1.3	E558S	Pathogenic	0.968
OPA1	O60313-1.3	E558T	Pathogenic	0.987
OPA1	O60313-1.3	E558V	Pathogenic	0.989
OPA1	O60313-1.3	E558W	Pathogenic	0.989
OPA1	O60313-1.3	E558Y	Pathogenic	0.991
OPA1	O60313-1.3	S559A	Pathogenic	0.596
OPA1	O60313-1.3	S559C	Pathogenic	0.867
OPA1	O60313-1.3	S559D	Pathogenic	0.741
OPA1	O60313-1.3	S559E	Pathogenic	0.751
OPA1	O60313-1.3	S559F	Pathogenic	0.882
OPA1	O60313-1.3	S559G	Pathogenic	0.841
OPA1	O60313-1.3	S559H	Pathogenic	0.926
OPA1	O60313-1.3	S559I	Pathogenic	0.885
OPA1	O60313-1.3	S559K	Pathogenic	0.665
OPA1	O60313-1.3	S559L	Pathogenic	0.894
OPA1	O60313-1.3	S559M	Pathogenic	0.818
OPA1	O60313-1.3	S559N	Pathogenic	0.53
OPA1	O60313-1.3	S559P	Pathogenic	0.891
OPA1	O60313-1.3	S559Q	Pathogenic	0.813
OPA1	O60313-1.3	S559R	Pathogenic	0.844
OPA1	O60313-1.3	S559T	Pathogenic	0.594
OPA1	O60313-1.3	S559V	Pathogenic	0.934
OPA1	O60313-1.3	S559W	Pathogenic	0.928
OPA1	O60313-1.3	S559Y	Pathogenic	0.94
OPA1	O60313-1.3	V560A	Pathogenic	0.911
OPA1	O60313-1.3	V560C	Pathogenic	0.983
OPA1	O60313-1.3	V560D	Pathogenic	0.99
OPA1	O60313-1.3	V560E	Pathogenic	0.976
OPA1	O60313-1.3	V560F	Pathogenic	0.976
OPA1	O60313-1.3	V560G	Pathogenic	0.994
OPA1	O60313-1.3	V560H	Pathogenic	0.996
OPA1	O60313-1.3	V560I	Neutral	0.376
OPA1	O60313-1.3	V560K	Pathogenic	0.964
OPA1	O60313-1.3	V560L	Pathogenic	0.848
OPA1	O60313-1.3	V560M	Pathogenic	0.895
OPA1	O60313-1.3	V560N	Pathogenic	0.992
OPA1	O60313-1.3	V560P	Pathogenic	0.993
OPA1	O60313-1.3	V560Q	Pathogenic	0.983
OPA1	O60313-1.3	V560R	Pathogenic	0.987
OPA1	O60313-1.3	V560S	Pathogenic	0.985
OPA1	O60313-1.3	V560T	Pathogenic	0.915
OPA1	O60313-1.3	V560W	Pathogenic	0.995
OPA1	O60313-1.3	V560Y	Pathogenic	0.982
OPA1	O60313-1.3	E561A	Pathogenic	0.988
OPA1	O60313-1.3	E561C	Pathogenic	0.999
OPA1	O60313-1.3	E561D	Pathogenic	0.883
OPA1	O60313-1.3	E561F	Pathogenic	0.995
OPA1	O60313-1.3	E561G	Pathogenic	0.997
OPA1	O60313-1.3	E561H	Pathogenic	0.973
OPA1	O60313-1.3	E561I	Pathogenic	0.995
OPA1	O60313-1.3	E561K	Pathogenic	0.946
OPA1	O60313-1.3	E561L	Pathogenic	0.995
OPA1	O60313-1.3	E561M	Pathogenic	0.991
OPA1	O60313-1.3	E561N	Pathogenic	0.986
OPA1	O60313-1.3	E561P	Pathogenic	0.984
OPA1	O60313-1.3	E561Q	Pathogenic	0.859
OPA1	O60313-1.3	E561R	Pathogenic	0.979
OPA1	O60313-1.3	E561S	Pathogenic	0.975
OPA1	O60313-1.3	E561T	Pathogenic	0.989
OPA1	O60313-1.3	E561V	Pathogenic	0.991
OPA1	O60313-1.3	E561W	Pathogenic	0.991
OPA1	O60313-1.3	E561Y	Pathogenic	0.993
OPA1	O60313-1.3	Q562A	Pathogenic	0.994
OPA1	O60313-1.3	Q562C	Pathogenic	0.999
OPA1	O60313-1.3	Q562D	Pathogenic	0.984
OPA1	O60313-1.3	Q562E	Pathogenic	0.9
OPA1	O60313-1.3	Q562F	Pathogenic	0.998
OPA1	O60313-1.3	Q562G	Pathogenic	0.998
OPA1	O60313-1.3	Q562H	Pathogenic	0.988
OPA1	O60313-1.3	Q562I	Pathogenic	0.998
OPA1	O60313-1.3	Q562K	Pathogenic	0.947
OPA1	O60313-1.3	Q562L	Pathogenic	0.994
OPA1	O60313-1.3	Q562M	Pathogenic	0.967
OPA1	O60313-1.3	Q562N	Pathogenic	0.987
OPA1	O60313-1.3	Q562P	Pathogenic	0.992
OPA1	O60313-1.3	Q562R	Pathogenic	0.944
OPA1	O60313-1.3	Q562S	Pathogenic	0.988
OPA1	O60313-1.3	Q562T	Pathogenic	0.995
OPA1	O60313-1.3	Q562V	Pathogenic	0.996
OPA1	O60313-1.3	Q562W	Pathogenic	0.988
OPA1	O60313-1.3	Q562Y	Pathogenic	0.99
OPA1	O60313-1.3	Q563A	Pathogenic	0.994
OPA1	O60313-1.3	Q563C	Pathogenic	0.999
OPA1	O60313-1.3	Q563D	Pathogenic	0.984
OPA1	O60313-1.3	Q563E	Pathogenic	0.9
OPA1	O60313-1.3	Q563F	Pathogenic	0.998
OPA1	O60313-1.3	Q563G	Pathogenic	0.998
OPA1	O60313-1.3	Q563H	Pathogenic	0.988
OPA1	O60313-1.3	Q563I	Pathogenic	0.998
OPA1	O60313-1.3	Q563K	Pathogenic	0.947
OPA1	O60313-1.3	Q563L	Pathogenic	0.994
OPA1	O60313-1.3	Q563M	Pathogenic	0.967
OPA1	O60313-1.3	Q563N	Pathogenic	0.987
OPA1	O60313-1.3	Q563P	Pathogenic	0.992
OPA1	O60313-1.3	Q563R	Pathogenic	0.944
OPA1	O60313-1.3	Q563S	Pathogenic	0.988
OPA1	O60313-1.3	Q563T	Pathogenic	0.995
OPA1	O60313-1.3	Q563V	Pathogenic	0.996
OPA1	O60313-1.3	Q563W	Pathogenic	0.988
OPA1	O60313-1.3	Q563Y	Pathogenic	0.99
OPA1	O60313-1.3	A564C	Pathogenic	0.982
OPA1	O60313-1.3	A564D	Pathogenic	0.997
OPA1	O60313-1.3	A564E	Pathogenic	0.991
OPA1	O60313-1.3	A564F	Pathogenic	0.995
OPA1	O60313-1.3	A564G	Pathogenic	0.987
OPA1	O60313-1.3	A564H	Pathogenic	0.998
OPA1	O60313-1.3	A564I	Pathogenic	0.985
OPA1	O60313-1.3	A564K	Pathogenic	0.987
OPA1	O60313-1.3	A564L	Pathogenic	0.986
OPA1	O60313-1.3	A564M	Pathogenic	0.991
OPA1	O60313-1.3	A564N	Pathogenic	0.997
OPA1	O60313-1.3	A564P	Pathogenic	0.995
OPA1	O60313-1.3	A564Q	Pathogenic	0.994
OPA1	O60313-1.3	A564R	Pathogenic	0.986
OPA1	O60313-1.3	A564S	Pathogenic	0.964
OPA1	O60313-1.3	A564T	Pathogenic	0.99
OPA1	O60313-1.3	A564V	Pathogenic	0.976
OPA1	O60313-1.3	A564W	Pathogenic	0.997
OPA1	O60313-1.3	A564Y	Pathogenic	0.997
OPA1	O60313-1.3	D565A	Pathogenic	0.997
OPA1	O60313-1.3	D565C	Pathogenic	0.998
OPA1	O60313-1.3	D565E	Pathogenic	0.914
OPA1	O60313-1.3	D565F	Pathogenic	0.995
OPA1	O60313-1.3	D565G	Pathogenic	0.992
OPA1	O60313-1.3	D565H	Pathogenic	0.992
OPA1	O60313-1.3	D565I	Pathogenic	0.995
OPA1	O60313-1.3	D565K	Pathogenic	0.995
OPA1	O60313-1.3	D565L	Pathogenic	0.999
OPA1	O60313-1.3	D565M	Pathogenic	0.997
OPA1	O60313-1.3	D565N	Pathogenic	0.969
OPA1	O60313-1.3	D565P	Pathogenic	0.988
OPA1	O60313-1.3	D565Q	Pathogenic	0.983
OPA1	O60313-1.3	D565R	Pathogenic	0.998
OPA1	O60313-1.3	D565S	Pathogenic	0.981
OPA1	O60313-1.3	D565T	Pathogenic	0.992
OPA1	O60313-1.3	D565V	Pathogenic	0.998
OPA1	O60313-1.3	D565W	Pathogenic	0.997
OPA1	O60313-1.3	D565Y	Pathogenic	0.998
OPA1	O60313-1.3	S566A	Neutral	0.073
OPA1	O60313-1.3	S566C	Neutral	0.257
OPA1	O60313-1.3	S566D	Neutral	0.132
OPA1	O60313-1.3	S566E	Neutral	0.138
OPA1	O60313-1.3	S566F	Neutral	0.285
OPA1	O60313-1.3	S566G	Neutral	0.219
OPA1	O60313-1.3	S566H	Neutral	0.401
OPA1	O60313-1.3	S566I	Neutral	0.291
OPA1	O60313-1.3	S566K	Neutral	0.095
OPA1	O60313-1.3	S566L	Neutral	0.311
OPA1	O60313-1.3	S566M	Neutral	0.193
OPA1	O60313-1.3	S566N	Neutral	0.057
OPA1	O60313-1.3	S566P	Neutral	0.303
OPA1	O60313-1.3	S566Q	Neutral	0.188
OPA1	O60313-1.3	S566R	Neutral	0.223
OPA1	O60313-1.3	S566T	Neutral	0.072
OPA1	O60313-1.3	S566V	Neutral	0.43
OPA1	O60313-1.3	S566W	Neutral	0.406
OPA1	O60313-1.3	S566Y	Neutral	0.454
OPA1	O60313-1.3	F567A	Pathogenic	0.996
OPA1	O60313-1.3	F567C	Pathogenic	0.998
OPA1	O60313-1.3	F567D	Pathogenic	0.996
OPA1	O60313-1.3	F567E	Pathogenic	0.997
OPA1	O60313-1.3	F567G	Pathogenic	0.998
OPA1	O60313-1.3	F567H	Pathogenic	0.988
OPA1	O60313-1.3	F567I	Pathogenic	0.992
OPA1	O60313-1.3	F567K	Pathogenic	0.996
OPA1	O60313-1.3	F567L	Pathogenic	0.992
OPA1	O60313-1.3	F567M	Pathogenic	0.987
OPA1	O60313-1.3	F567N	Pathogenic	0.997
OPA1	O60313-1.3	F567P	Pathogenic	1.0
OPA1	O60313-1.3	F567Q	Pathogenic	0.998
OPA1	O60313-1.3	F567R	Pathogenic	0.996
OPA1	O60313-1.3	F567S	Pathogenic	0.994
OPA1	O60313-1.3	F567T	Pathogenic	0.996
OPA1	O60313-1.3	F567V	Pathogenic	0.995
OPA1	O60313-1.3	F567W	Pathogenic	0.965
OPA1	O60313-1.3	F567Y	Pathogenic	0.718
OPA1	O60313-1.3	K568A	Pathogenic	0.985
OPA1	O60313-1.3	K568C	Pathogenic	0.997
OPA1	O60313-1.3	K568D	Pathogenic	0.995
OPA1	O60313-1.3	K568E	Pathogenic	0.955
OPA1	O60313-1.3	K568F	Pathogenic	0.994
OPA1	O60313-1.3	K568G	Pathogenic	0.996
OPA1	O60313-1.3	K568H	Pathogenic	0.989
OPA1	O60313-1.3	K568I	Pathogenic	0.994
OPA1	O60313-1.3	K568L	Pathogenic	0.985
OPA1	O60313-1.3	K568M	Pathogenic	0.971
OPA1	O60313-1.3	K568N	Pathogenic	0.983
OPA1	O60313-1.3	K568P	Pathogenic	0.98
OPA1	O60313-1.3	K568Q	Pathogenic	0.936
OPA1	O60313-1.3	K568R	Pathogenic	0.912
OPA1	O60313-1.3	K568S	Pathogenic	0.969
OPA1	O60313-1.3	K568T	Pathogenic	0.987
OPA1	O60313-1.3	K568V	Pathogenic	0.989
OPA1	O60313-1.3	K568W	Pathogenic	0.991
OPA1	O60313-1.3	K568Y	Pathogenic	0.992
OPA1	O60313-1.3	A569C	Pathogenic	0.973
OPA1	O60313-1.3	A569D	Pathogenic	0.995
OPA1	O60313-1.3	A569E	Pathogenic	0.987
OPA1	O60313-1.3	A569F	Pathogenic	0.992
OPA1	O60313-1.3	A569G	Pathogenic	0.981
OPA1	O60313-1.3	A569H	Pathogenic	0.998
OPA1	O60313-1.3	A569I	Pathogenic	0.977
OPA1	O60313-1.3	A569K	Pathogenic	0.98
OPA1	O60313-1.3	A569L	Pathogenic	0.979
OPA1	O60313-1.3	A569M	Pathogenic	0.987
OPA1	O60313-1.3	A569N	Pathogenic	0.996
OPA1	O60313-1.3	A569P	Pathogenic	0.993
OPA1	O60313-1.3	A569Q	Pathogenic	0.991
OPA1	O60313-1.3	A569R	Pathogenic	0.979
OPA1	O60313-1.3	A569S	Pathogenic	0.947
OPA1	O60313-1.3	A569T	Pathogenic	0.984
OPA1	O60313-1.3	A569V	Pathogenic	0.965
OPA1	O60313-1.3	A569W	Pathogenic	0.995
OPA1	O60313-1.3	A569Y	Pathogenic	0.996
OPA1	O60313-1.3	T570A	Pathogenic	0.766
OPA1	O60313-1.3	T570C	Pathogenic	0.846
OPA1	O60313-1.3	T570D	Pathogenic	0.81
OPA1	O60313-1.3	T570E	Pathogenic	0.82
OPA1	O60313-1.3	T570F	Pathogenic	0.87
OPA1	O60313-1.3	T570G	Pathogenic	0.955
OPA1	O60313-1.3	T570H	Pathogenic	0.963
OPA1	O60313-1.3	T570I	Pathogenic	0.704
OPA1	O60313-1.3	T570K	Pathogenic	0.75
OPA1	O60313-1.3	T570L	Pathogenic	0.723
OPA1	O60313-1.3	T570M	Pathogenic	0.8
OPA1	O60313-1.3	T570N	Pathogenic	0.631
OPA1	O60313-1.3	T570P	Pathogenic	0.877
OPA1	O60313-1.3	T570Q	Pathogenic	0.868
OPA1	O60313-1.3	T570R	Pathogenic	0.738
OPA1	O60313-1.3	T570S	Neutral	0.481
OPA1	O60313-1.3	T570V	Pathogenic	0.601
OPA1	O60313-1.3	T570W	Pathogenic	0.798
OPA1	O60313-1.3	T570Y	Pathogenic	0.933
OPA1	O60313-1.3	R571A	Pathogenic	0.978
OPA1	O60313-1.3	R571C	Pathogenic	0.995
OPA1	O60313-1.3	R571D	Pathogenic	0.997
OPA1	O60313-1.3	R571E	Pathogenic	0.977
OPA1	O60313-1.3	R571F	Pathogenic	0.992
OPA1	O60313-1.3	R571G	Pathogenic	0.994
OPA1	O60313-1.3	R571H	Pathogenic	0.956
OPA1	O60313-1.3	R571I	Pathogenic	0.992
OPA1	O60313-1.3	R571K	Pathogenic	0.886
OPA1	O60313-1.3	R571L	Pathogenic	0.978
OPA1	O60313-1.3	R571M	Pathogenic	0.96
OPA1	O60313-1.3	R571N	Pathogenic	0.975
OPA1	O60313-1.3	R571P	Pathogenic	0.99
OPA1	O60313-1.3	R571Q	Pathogenic	0.911
OPA1	O60313-1.3	R571S	Pathogenic	0.984
OPA1	O60313-1.3	R571T	Pathogenic	0.981
OPA1	O60313-1.3	R571V	Pathogenic	0.995
OPA1	O60313-1.3	R571W	Pathogenic	0.988
OPA1	O60313-1.3	R571Y	Pathogenic	0.989
OPA1	O60313-1.3	F572A	Pathogenic	0.993
OPA1	O60313-1.3	F572C	Pathogenic	0.997
OPA1	O60313-1.3	F572D	Pathogenic	0.994
OPA1	O60313-1.3	F572E	Pathogenic	0.995
OPA1	O60313-1.3	F572G	Pathogenic	0.997
OPA1	O60313-1.3	F572H	Pathogenic	0.982
OPA1	O60313-1.3	F572I	Pathogenic	0.988
OPA1	O60313-1.3	F572K	Pathogenic	0.994
OPA1	O60313-1.3	F572L	Pathogenic	0.988
OPA1	O60313-1.3	F572M	Pathogenic	0.981
OPA1	O60313-1.3	F572N	Pathogenic	0.995
OPA1	O60313-1.3	F572P	Pathogenic	1.0
OPA1	O60313-1.3	F572Q	Pathogenic	0.997
OPA1	O60313-1.3	F572R	Pathogenic	0.994
OPA1	O60313-1.3	F572S	Pathogenic	0.991
OPA1	O60313-1.3	F572T	Pathogenic	0.994
OPA1	O60313-1.3	F572V	Pathogenic	0.993
OPA1	O60313-1.3	F572W	Pathogenic	0.948
OPA1	O60313-1.3	F572Y	Pathogenic	0.629
OPA1	O60313-1.3	N573A	Pathogenic	0.996
OPA1	O60313-1.3	N573C	Pathogenic	0.998
OPA1	O60313-1.3	N573D	Pathogenic	0.961
OPA1	O60313-1.3	N573E	Pathogenic	0.987
OPA1	O60313-1.3	N573F	Pathogenic	0.995
OPA1	O60313-1.3	N573G	Pathogenic	0.976
OPA1	O60313-1.3	N573H	Pathogenic	0.932
OPA1	O60313-1.3	N573I	Pathogenic	0.995
OPA1	O60313-1.3	N573K	Pathogenic	0.981
OPA1	O60313-1.3	N573L	Pathogenic	0.996
OPA1	O60313-1.3	N573M	Pathogenic	0.992
OPA1	O60313-1.3	N573P	Pathogenic	0.995
OPA1	O60313-1.3	N573Q	Pathogenic	0.982
OPA1	O60313-1.3	N573R	Pathogenic	0.98
OPA1	O60313-1.3	N573S	Pathogenic	0.941
OPA1	O60313-1.3	N573T	Pathogenic	0.975
OPA1	O60313-1.3	N573V	Pathogenic	0.997
OPA1	O60313-1.3	N573W	Pathogenic	0.997
OPA1	O60313-1.3	N573Y	Pathogenic	0.993
OPA1	O60313-1.3	L574A	Pathogenic	0.974
OPA1	O60313-1.3	L574C	Pathogenic	0.987
OPA1	O60313-1.3	L574D	Pathogenic	0.997
OPA1	O60313-1.3	L574E	Pathogenic	0.994
OPA1	O60313-1.3	L574F	Pathogenic	0.981
OPA1	O60313-1.3	L574G	Pathogenic	0.998
OPA1	O60313-1.3	L574H	Pathogenic	0.997
OPA1	O60313-1.3	L574I	Pathogenic	0.86
OPA1	O60313-1.3	L574K	Pathogenic	0.975
OPA1	O60313-1.3	L574M	Pathogenic	0.815
OPA1	O60313-1.3	L574N	Pathogenic	0.993
OPA1	O60313-1.3	L574P	Pathogenic	0.998
OPA1	O60313-1.3	L574Q	Pathogenic	0.988
OPA1	O60313-1.3	L574R	Pathogenic	0.973
OPA1	O60313-1.3	L574S	Pathogenic	0.988
OPA1	O60313-1.3	L574T	Pathogenic	0.975
OPA1	O60313-1.3	L574V	Pathogenic	0.921
OPA1	O60313-1.3	L574W	Pathogenic	0.996
OPA1	O60313-1.3	L574Y	Pathogenic	0.987
OPA1	O60313-1.3	E575A	Pathogenic	0.985
OPA1	O60313-1.3	E575C	Pathogenic	0.999
OPA1	O60313-1.3	E575D	Pathogenic	0.858
OPA1	O60313-1.3	E575F	Pathogenic	0.993
OPA1	O60313-1.3	E575G	Pathogenic	0.996
OPA1	O60313-1.3	E575H	Pathogenic	0.967
OPA1	O60313-1.3	E575I	Pathogenic	0.993
OPA1	O60313-1.3	E575K	Pathogenic	0.933
OPA1	O60313-1.3	E575L	Pathogenic	0.994
OPA1	O60313-1.3	E575M	Pathogenic	0.989
OPA1	O60313-1.3	E575N	Pathogenic	0.983
OPA1	O60313-1.3	E575P	Pathogenic	0.979
OPA1	O60313-1.3	E575Q	Pathogenic	0.83
OPA1	O60313-1.3	E575R	Pathogenic	0.974
OPA1	O60313-1.3	E575S	Pathogenic	0.969
OPA1	O60313-1.3	E575T	Pathogenic	0.987
OPA1	O60313-1.3	E575V	Pathogenic	0.989
OPA1	O60313-1.3	E575W	Pathogenic	0.989
OPA1	O60313-1.3	E575Y	Pathogenic	0.991
OPA1	O60313-1.3	T576A	Pathogenic	0.985
OPA1	O60313-1.3	T576C	Pathogenic	0.991
OPA1	O60313-1.3	T576D	Pathogenic	0.988
OPA1	O60313-1.3	T576E	Pathogenic	0.989
OPA1	O60313-1.3	T576F	Pathogenic	0.993
OPA1	O60313-1.3	T576G	Pathogenic	0.998
OPA1	O60313-1.3	T576H	Pathogenic	0.998
OPA1	O60313-1.3	T576I	Pathogenic	0.979
OPA1	O60313-1.3	T576K	Pathogenic	0.984
OPA1	O60313-1.3	T576L	Pathogenic	0.981
OPA1	O60313-1.3	T576M	Pathogenic	0.988
OPA1	O60313-1.3	T576N	Pathogenic	0.971
OPA1	O60313-1.3	T576P	Pathogenic	0.993
OPA1	O60313-1.3	T576Q	Pathogenic	0.992
OPA1	O60313-1.3	T576R	Pathogenic	0.982
OPA1	O60313-1.3	T576S	Pathogenic	0.949
OPA1	O60313-1.3	T576V	Pathogenic	0.968
OPA1	O60313-1.3	T576W	Pathogenic	0.987
OPA1	O60313-1.3	T576Y	Pathogenic	0.996
OPA1	O60313-1.3	E577A	Pathogenic	0.985
OPA1	O60313-1.3	E577C	Pathogenic	0.999
OPA1	O60313-1.3	E577D	Pathogenic	0.858
OPA1	O60313-1.3	E577F	Pathogenic	0.993
OPA1	O60313-1.3	E577G	Pathogenic	0.996
OPA1	O60313-1.3	E577H	Pathogenic	0.967
OPA1	O60313-1.3	E577I	Pathogenic	0.993
OPA1	O60313-1.3	E577K	Pathogenic	0.933
OPA1	O60313-1.3	E577L	Pathogenic	0.994
OPA1	O60313-1.3	E577M	Pathogenic	0.989
OPA1	O60313-1.3	E577N	Pathogenic	0.983
OPA1	O60313-1.3	E577P	Pathogenic	0.979
OPA1	O60313-1.3	E577Q	Pathogenic	0.83
OPA1	O60313-1.3	E577R	Pathogenic	0.974
OPA1	O60313-1.3	E577S	Pathogenic	0.969
OPA1	O60313-1.3	E577T	Pathogenic	0.987
OPA1	O60313-1.3	E577V	Pathogenic	0.989
OPA1	O60313-1.3	E577W	Pathogenic	0.989
OPA1	O60313-1.3	E577Y	Pathogenic	0.991
OPA1	O60313-1.3	W578A	Pathogenic	0.997
OPA1	O60313-1.3	W578C	Pathogenic	0.996
OPA1	O60313-1.3	W578D	Pathogenic	0.997
OPA1	O60313-1.3	W578E	Pathogenic	0.994
OPA1	O60313-1.3	W578F	Pathogenic	0.96
OPA1	O60313-1.3	W578G	Pathogenic	0.988
OPA1	O60313-1.3	W578H	Pathogenic	0.992
OPA1	O60313-1.3	W578I	Pathogenic	0.999
OPA1	O60313-1.3	W578K	Pathogenic	0.993
OPA1	O60313-1.3	W578L	Pathogenic	0.998
OPA1	O60313-1.3	W578M	Pathogenic	0.991
OPA1	O60313-1.3	W578N	Pathogenic	0.998
OPA1	O60313-1.3	W578P	Pathogenic	0.999
OPA1	O60313-1.3	W578Q	Pathogenic	0.988
OPA1	O60313-1.3	W578R	Pathogenic	0.993
OPA1	O60313-1.3	W578S	Pathogenic	0.996
OPA1	O60313-1.3	W578T	Pathogenic	0.992
OPA1	O60313-1.3	W578V	Pathogenic	0.999
OPA1	O60313-1.3	W578Y	Pathogenic	0.798
OPA1	O60313-1.3	K579A	Pathogenic	0.977
OPA1	O60313-1.3	K579C	Pathogenic	0.995
OPA1	O60313-1.3	K579D	Pathogenic	0.992
OPA1	O60313-1.3	K579E	Pathogenic	0.934
OPA1	O60313-1.3	K579F	Pathogenic	0.992
OPA1	O60313-1.3	K579G	Pathogenic	0.993
OPA1	O60313-1.3	K579H	Pathogenic	0.984
OPA1	O60313-1.3	K579I	Pathogenic	0.991
OPA1	O60313-1.3	K579L	Pathogenic	0.977
OPA1	O60313-1.3	K579M	Pathogenic	0.958
OPA1	O60313-1.3	K579N	Pathogenic	0.974
OPA1	O60313-1.3	K579P	Pathogenic	0.97
OPA1	O60313-1.3	K579Q	Pathogenic	0.907
OPA1	O60313-1.3	K579R	Pathogenic	0.874
OPA1	O60313-1.3	K579S	Pathogenic	0.954
OPA1	O60313-1.3	K579T	Pathogenic	0.98
OPA1	O60313-1.3	K579V	Pathogenic	0.984
OPA1	O60313-1.3	K579W	Pathogenic	0.986
OPA1	O60313-1.3	K579Y	Pathogenic	0.988
OPA1	O60313-1.3	N580A	Pathogenic	0.996
OPA1	O60313-1.3	N580C	Pathogenic	0.998
OPA1	O60313-1.3	N580D	Pathogenic	0.961
OPA1	O60313-1.3	N580E	Pathogenic	0.987
OPA1	O60313-1.3	N580F	Pathogenic	0.995
OPA1	O60313-1.3	N580G	Pathogenic	0.976
OPA1	O60313-1.3	N580H	Pathogenic	0.932
OPA1	O60313-1.3	N580I	Pathogenic	0.995
OPA1	O60313-1.3	N580K	Pathogenic	0.981
OPA1	O60313-1.3	N580L	Pathogenic	0.996
OPA1	O60313-1.3	N580M	Pathogenic	0.992
OPA1	O60313-1.3	N580P	Pathogenic	0.995
OPA1	O60313-1.3	N580Q	Pathogenic	0.982
OPA1	O60313-1.3	N580R	Pathogenic	0.98
OPA1	O60313-1.3	N580S	Pathogenic	0.941
OPA1	O60313-1.3	N580T	Pathogenic	0.975
OPA1	O60313-1.3	N580V	Pathogenic	0.997
OPA1	O60313-1.3	N580W	Pathogenic	0.997
OPA1	O60313-1.3	N580Y	Pathogenic	0.993
OPA1	O60313-1.3	N581A	Pathogenic	0.992
OPA1	O60313-1.3	N581C	Pathogenic	0.996
OPA1	O60313-1.3	N581D	Pathogenic	0.921
OPA1	O60313-1.3	N581E	Pathogenic	0.974
OPA1	O60313-1.3	N581F	Pathogenic	0.99
OPA1	O60313-1.3	N581G	Pathogenic	0.951
OPA1	O60313-1.3	N581H	Pathogenic	0.867
OPA1	O60313-1.3	N581I	Pathogenic	0.99
OPA1	O60313-1.3	N581K	Pathogenic	0.961
OPA1	O60313-1.3	N581L	Pathogenic	0.991
OPA1	O60313-1.3	N581M	Pathogenic	0.983
OPA1	O60313-1.3	N581P	Pathogenic	0.99
OPA1	O60313-1.3	N581Q	Pathogenic	0.964
OPA1	O60313-1.3	N581R	Pathogenic	0.958
OPA1	O60313-1.3	N581S	Pathogenic	0.884
OPA1	O60313-1.3	N581T	Pathogenic	0.948
OPA1	O60313-1.3	N581V	Pathogenic	0.994
OPA1	O60313-1.3	N581W	Pathogenic	0.994
OPA1	O60313-1.3	N581Y	Pathogenic	0.986
OPA1	O60313-1.3	Y582A	Pathogenic	0.951
OPA1	O60313-1.3	Y582C	Pathogenic	0.974
OPA1	O60313-1.3	Y582D	Pathogenic	0.959
OPA1	O60313-1.3	Y582E	Pathogenic	0.906
OPA1	O60313-1.3	Y582F	Neutral	0.095
OPA1	O60313-1.3	Y582G	Pathogenic	0.975
OPA1	O60313-1.3	Y582H	Neutral	0.222
OPA1	O60313-1.3	Y582I	Pathogenic	0.875
OPA1	O60313-1.3	Y582K	Pathogenic	0.885
OPA1	O60313-1.3	Y582L	Pathogenic	0.885
OPA1	O60313-1.3	Y582M	Pathogenic	0.922
OPA1	O60313-1.3	Y582N	Pathogenic	0.905
OPA1	O60313-1.3	Y582P	Pathogenic	0.989
OPA1	O60313-1.3	Y582Q	Pathogenic	0.832
OPA1	O60313-1.3	Y582R	Pathogenic	0.883
OPA1	O60313-1.3	Y582S	Pathogenic	0.936
OPA1	O60313-1.3	Y582T	Pathogenic	0.954
OPA1	O60313-1.3	Y582V	Pathogenic	0.918
OPA1	O60313-1.3	Y582W	Neutral	0.158
OPA1	O60313-1.3	P583A	Pathogenic	0.994
OPA1	O60313-1.3	P583C	Pathogenic	0.999
OPA1	O60313-1.3	P583D	Pathogenic	0.985
OPA1	O60313-1.3	P583E	Pathogenic	0.986
OPA1	O60313-1.3	P583F	Pathogenic	1.0
OPA1	O60313-1.3	P583G	Pathogenic	0.997
OPA1	O60313-1.3	P583H	Pathogenic	0.998
OPA1	O60313-1.3	P583I	Pathogenic	0.999
OPA1	O60313-1.3	P583K	Pathogenic	0.979
OPA1	O60313-1.3	P583L	Pathogenic	0.999
OPA1	O60313-1.3	P583M	Pathogenic	0.998
OPA1	O60313-1.3	P583N	Pathogenic	0.996
OPA1	O60313-1.3	P583Q	Pathogenic	0.99
OPA1	O60313-1.3	P583R	Pathogenic	0.992
OPA1	O60313-1.3	P583S	Pathogenic	0.992
OPA1	O60313-1.3	P583T	Pathogenic	0.994
OPA1	O60313-1.3	P583V	Pathogenic	0.998
OPA1	O60313-1.3	P583W	Pathogenic	0.999
OPA1	O60313-1.3	P583Y	Pathogenic	0.999
OPA1	O60313-1.3	R584A	Pathogenic	0.976
OPA1	O60313-1.3	R584C	Pathogenic	0.995
OPA1	O60313-1.3	R584D	Pathogenic	0.997
OPA1	O60313-1.3	R584E	Pathogenic	0.975
OPA1	O60313-1.3	R584F	Pathogenic	0.991
OPA1	O60313-1.3	R584G	Pathogenic	0.993
OPA1	O60313-1.3	R584H	Pathogenic	0.952
OPA1	O60313-1.3	R584I	Pathogenic	0.991
OPA1	O60313-1.3	R584K	Pathogenic	0.875
OPA1	O60313-1.3	R584L	Pathogenic	0.976
OPA1	O60313-1.3	R584M	Pathogenic	0.956
OPA1	O60313-1.3	R584N	Pathogenic	0.973
OPA1	O60313-1.3	R584P	Pathogenic	0.989
OPA1	O60313-1.3	R584Q	Pathogenic	0.903
OPA1	O60313-1.3	R584S	Pathogenic	0.983
OPA1	O60313-1.3	R584T	Pathogenic	0.979
OPA1	O60313-1.3	R584V	Pathogenic	0.994
OPA1	O60313-1.3	R584W	Pathogenic	0.987
OPA1	O60313-1.3	R584Y	Pathogenic	0.988
OPA1	O60313-1.3	L585A	Pathogenic	0.946
OPA1	O60313-1.3	L585C	Pathogenic	0.972
OPA1	O60313-1.3	L585D	Pathogenic	0.994
OPA1	O60313-1.3	L585E	Pathogenic	0.986
OPA1	O60313-1.3	L585F	Pathogenic	0.96
OPA1	O60313-1.3	L585G	Pathogenic	0.997
OPA1	O60313-1.3	L585H	Pathogenic	0.993
OPA1	O60313-1.3	L585I	Pathogenic	0.745
OPA1	O60313-1.3	L585K	Pathogenic	0.949
OPA1	O60313-1.3	L585M	Pathogenic	0.676
OPA1	O60313-1.3	L585N	Pathogenic	0.986
OPA1	O60313-1.3	L585P	Pathogenic	0.996
OPA1	O60313-1.3	L585Q	Pathogenic	0.974
OPA1	O60313-1.3	L585R	Pathogenic	0.946
OPA1	O60313-1.3	L585S	Pathogenic	0.974
OPA1	O60313-1.3	L585T	Pathogenic	0.949
OPA1	O60313-1.3	L585V	Pathogenic	0.847
OPA1	O60313-1.3	L585W	Pathogenic	0.992
OPA1	O60313-1.3	L585Y	Pathogenic	0.974
OPA1	O60313-1.3	R586A	Pathogenic	0.978
OPA1	O60313-1.3	R586C	Pathogenic	0.995
OPA1	O60313-1.3	R586D	Pathogenic	0.997
OPA1	O60313-1.3	R586E	Pathogenic	0.977
OPA1	O60313-1.3	R586F	Pathogenic	0.992
OPA1	O60313-1.3	R586G	Pathogenic	0.994
OPA1	O60313-1.3	R586H	Pathogenic	0.956
OPA1	O60313-1.3	R586I	Pathogenic	0.992
OPA1	O60313-1.3	R586K	Pathogenic	0.886
OPA1	O60313-1.3	R586L	Pathogenic	0.978
OPA1	O60313-1.3	R586M	Pathogenic	0.96
OPA1	O60313-1.3	R586N	Pathogenic	0.975
OPA1	O60313-1.3	R586P	Pathogenic	0.99
OPA1	O60313-1.3	R586Q	Pathogenic	0.911
OPA1	O60313-1.3	R586S	Pathogenic	0.984
OPA1	O60313-1.3	R586T	Pathogenic	0.981
OPA1	O60313-1.3	R586V	Pathogenic	0.995
OPA1	O60313-1.3	R586W	Pathogenic	0.988
OPA1	O60313-1.3	R586Y	Pathogenic	0.989
OPA1	O60313-1.3	E587A	Pathogenic	0.985
OPA1	O60313-1.3	E587C	Pathogenic	0.999
OPA1	O60313-1.3	E587D	Pathogenic	0.858
OPA1	O60313-1.3	E587F	Pathogenic	0.993
OPA1	O60313-1.3	E587G	Pathogenic	0.996
OPA1	O60313-1.3	E587H	Pathogenic	0.967
OPA1	O60313-1.3	E587I	Pathogenic	0.993
OPA1	O60313-1.3	E587K	Pathogenic	0.933
OPA1	O60313-1.3	E587L	Pathogenic	0.994
OPA1	O60313-1.3	E587M	Pathogenic	0.989
OPA1	O60313-1.3	E587N	Pathogenic	0.983
OPA1	O60313-1.3	E587P	Pathogenic	0.979
OPA1	O60313-1.3	E587Q	Pathogenic	0.83
OPA1	O60313-1.3	E587R	Pathogenic	0.974
OPA1	O60313-1.3	E587S	Pathogenic	0.969
OPA1	O60313-1.3	E587T	Pathogenic	0.987
OPA1	O60313-1.3	E587V	Pathogenic	0.989
OPA1	O60313-1.3	E587W	Pathogenic	0.989
OPA1	O60313-1.3	E587Y	Pathogenic	0.991
OPA1	O60313-1.3	L588A	Pathogenic	0.94
OPA1	O60313-1.3	L588C	Pathogenic	0.969
OPA1	O60313-1.3	L588D	Pathogenic	0.994
OPA1	O60313-1.3	L588E	Pathogenic	0.985
OPA1	O60313-1.3	L588F	Pathogenic	0.955
OPA1	O60313-1.3	L588G	Pathogenic	0.996
OPA1	O60313-1.3	L588H	Pathogenic	0.993
OPA1	O60313-1.3	L588I	Pathogenic	0.721
OPA1	O60313-1.3	L588K	Pathogenic	0.943
OPA1	O60313-1.3	L588M	Pathogenic	0.649
OPA1	O60313-1.3	L588N	Pathogenic	0.985
OPA1	O60313-1.3	L588P	Pathogenic	0.995
OPA1	O60313-1.3	L588Q	Pathogenic	0.971
OPA1	O60313-1.3	L588R	Pathogenic	0.939
OPA1	O60313-1.3	L588S	Pathogenic	0.971
OPA1	O60313-1.3	L588T	Pathogenic	0.943
OPA1	O60313-1.3	L588V	Pathogenic	0.831
OPA1	O60313-1.3	L588W	Pathogenic	0.991
OPA1	O60313-1.3	L588Y	Pathogenic	0.971
OPA1	O60313-1.3	D589A	Pathogenic	0.985
OPA1	O60313-1.3	D589C	Pathogenic	0.991
OPA1	O60313-1.3	D589E	Pathogenic	0.687
OPA1	O60313-1.3	D589F	Pathogenic	0.978
OPA1	O60313-1.3	D589G	Pathogenic	0.965
OPA1	O60313-1.3	D589H	Pathogenic	0.962
OPA1	O60313-1.3	D589I	Pathogenic	0.979
OPA1	O60313-1.3	D589K	Pathogenic	0.978
OPA1	O60313-1.3	D589L	Pathogenic	0.993
OPA1	O60313-1.3	D589M	Pathogenic	0.987
OPA1	O60313-1.3	D589N	Pathogenic	0.866
OPA1	O60313-1.3	D589P	Pathogenic	0.943
OPA1	O60313-1.3	D589Q	Pathogenic	0.925
OPA1	O60313-1.3	D589R	Pathogenic	0.992
OPA1	O60313-1.3	D589S	Pathogenic	0.914
OPA1	O60313-1.3	D589T	Pathogenic	0.962
OPA1	O60313-1.3	D589V	Pathogenic	0.988
OPA1	O60313-1.3	D589W	Pathogenic	0.987
OPA1	O60313-1.3	D589Y	Pathogenic	0.989
OPA1	O60313-1.3	R590A	Pathogenic	0.978
OPA1	O60313-1.3	R590C	Pathogenic	0.995
OPA1	O60313-1.3	R590D	Pathogenic	0.997
OPA1	O60313-1.3	R590E	Pathogenic	0.977
OPA1	O60313-1.3	R590F	Pathogenic	0.992
OPA1	O60313-1.3	R590G	Pathogenic	0.994
OPA1	O60313-1.3	R590H	Pathogenic	0.956
OPA1	O60313-1.3	R590I	Pathogenic	0.992
OPA1	O60313-1.3	R590K	Pathogenic	0.886
OPA1	O60313-1.3	R590L	Pathogenic	0.978
OPA1	O60313-1.3	R590M	Pathogenic	0.96
OPA1	O60313-1.3	R590N	Pathogenic	0.975
OPA1	O60313-1.3	R590P	Pathogenic	0.99
OPA1	O60313-1.3	R590Q	Pathogenic	0.911
OPA1	O60313-1.3	R590S	Pathogenic	0.984
OPA1	O60313-1.3	R590T	Pathogenic	0.981
OPA1	O60313-1.3	R590V	Pathogenic	0.995
OPA1	O60313-1.3	R590W	Pathogenic	0.988
OPA1	O60313-1.3	R590Y	Pathogenic	0.989
OPA1	O60313-1.3	N591A	Pathogenic	0.949
OPA1	O60313-1.3	N591C	Pathogenic	0.969
OPA1	O60313-1.3	N591D	Pathogenic	0.623
OPA1	O60313-1.3	N591E	Pathogenic	0.84
OPA1	O60313-1.3	N591F	Pathogenic	0.931
OPA1	O60313-1.3	N591G	Pathogenic	0.733
OPA1	O60313-1.3	N591H	Neutral	0.481
OPA1	O60313-1.3	N591I	Pathogenic	0.933
OPA1	O60313-1.3	N591K	Pathogenic	0.776
OPA1	O60313-1.3	N591L	Pathogenic	0.938
OPA1	O60313-1.3	N591M	Pathogenic	0.89
OPA1	O60313-1.3	N591P	Pathogenic	0.933
OPA1	O60313-1.3	N591Q	Pathogenic	0.79
OPA1	O60313-1.3	N591R	Pathogenic	0.765
OPA1	O60313-1.3	N591S	Pathogenic	0.519
OPA1	O60313-1.3	N591T	Pathogenic	0.72
OPA1	O60313-1.3	N591V	Pathogenic	0.962
OPA1	O60313-1.3	N591W	Pathogenic	0.958
OPA1	O60313-1.3	N591Y	Pathogenic	0.907
OPA1	O60313-1.3	E592A	Pathogenic	0.982
OPA1	O60313-1.3	E592C	Pathogenic	0.999
OPA1	O60313-1.3	E592D	Pathogenic	0.838
OPA1	O60313-1.3	E592F	Pathogenic	0.992
OPA1	O60313-1.3	E592G	Pathogenic	0.995
OPA1	O60313-1.3	E592H	Pathogenic	0.962
OPA1	O60313-1.3	E592I	Pathogenic	0.992
OPA1	O60313-1.3	E592K	Pathogenic	0.922
OPA1	O60313-1.3	E592L	Pathogenic	0.993
OPA1	O60313-1.3	E592M	Pathogenic	0.987
OPA1	O60313-1.3	E592N	Pathogenic	0.98
OPA1	O60313-1.3	E592P	Pathogenic	0.976
OPA1	O60313-1.3	E592Q	Pathogenic	0.807
OPA1	O60313-1.3	E592R	Pathogenic	0.97
OPA1	O60313-1.3	E592S	Pathogenic	0.963
OPA1	O60313-1.3	E592T	Pathogenic	0.984
OPA1	O60313-1.3	E592V	Pathogenic	0.988
OPA1	O60313-1.3	E592W	Pathogenic	0.987
OPA1	O60313-1.3	E592Y	Pathogenic	0.989
OPA1	O60313-1.3	L593A	Pathogenic	0.97
OPA1	O60313-1.3	L593C	Pathogenic	0.984
OPA1	O60313-1.3	L593D	Pathogenic	0.997
OPA1	O60313-1.3	L593E	Pathogenic	0.992
OPA1	O60313-1.3	L593F	Pathogenic	0.977
OPA1	O60313-1.3	L593G	Pathogenic	0.998
OPA1	O60313-1.3	L593H	Pathogenic	0.996
OPA1	O60313-1.3	L593I	Pathogenic	0.84
OPA1	O60313-1.3	L593K	Pathogenic	0.971
OPA1	O60313-1.3	L593M	Pathogenic	0.79
OPA1	O60313-1.3	L593N	Pathogenic	0.992
OPA1	O60313-1.3	L593P	Pathogenic	0.998
OPA1	O60313-1.3	L593Q	Pathogenic	0.985
OPA1	O60313-1.3	L593R	Pathogenic	0.969
OPA1	O60313-1.3	L593S	Pathogenic	0.986
OPA1	O60313-1.3	L593T	Pathogenic	0.971
OPA1	O60313-1.3	L593V	Pathogenic	0.909
OPA1	O60313-1.3	L593W	Pathogenic	0.995
OPA1	O60313-1.3	L593Y	Pathogenic	0.985
OPA1	O60313-1.3	F594A	Pathogenic	0.964
OPA1	O60313-1.3	F594C	Pathogenic	0.982
OPA1	O60313-1.3	F594D	Pathogenic	0.97
OPA1	O60313-1.3	F594E	Pathogenic	0.975
OPA1	O60313-1.3	F594G	Pathogenic	0.982
OPA1	O60313-1.3	F594H	Pathogenic	0.905
OPA1	O60313-1.3	F594I	Pathogenic	0.938
OPA1	O60313-1.3	F594K	Pathogenic	0.968
OPA1	O60313-1.3	F594L	Pathogenic	0.934
OPA1	O60313-1.3	F594M	Pathogenic	0.902
OPA1	O60313-1.3	F594N	Pathogenic	0.974
OPA1	O60313-1.3	F594P	Pathogenic	0.997
OPA1	O60313-1.3	F594Q	Pathogenic	0.983
OPA1	O60313-1.3	F594R	Pathogenic	0.967
OPA1	O60313-1.3	F594S	Pathogenic	0.953
OPA1	O60313-1.3	F594T	Pathogenic	0.966
OPA1	O60313-1.3	F594V	Pathogenic	0.961
OPA1	O60313-1.3	F594W	Pathogenic	0.766
OPA1	O60313-1.3	F594Y	Neutral	0.232
OPA1	O60313-1.3	E595A	Pathogenic	0.958
OPA1	O60313-1.3	E595C	Pathogenic	0.997
OPA1	O60313-1.3	E595D	Pathogenic	0.685
OPA1	O60313-1.3	E595F	Pathogenic	0.981
OPA1	O60313-1.3	E595G	Pathogenic	0.988
OPA1	O60313-1.3	E595H	Pathogenic	0.913
OPA1	O60313-1.3	E595I	Pathogenic	0.982
OPA1	O60313-1.3	E595K	Pathogenic	0.833
OPA1	O60313-1.3	E595L	Pathogenic	0.984
OPA1	O60313-1.3	E595M	Pathogenic	0.969
OPA1	O60313-1.3	E595N	Pathogenic	0.953
OPA1	O60313-1.3	E595P	Pathogenic	0.945
OPA1	O60313-1.3	E595Q	Pathogenic	0.637
OPA1	O60313-1.3	E595R	Pathogenic	0.932
OPA1	O60313-1.3	E595S	Pathogenic	0.917
OPA1	O60313-1.3	E595T	Pathogenic	0.964
OPA1	O60313-1.3	E595V	Pathogenic	0.971
OPA1	O60313-1.3	E595W	Pathogenic	0.969
OPA1	O60313-1.3	E595Y	Pathogenic	0.974
OPA1	O60313-1.3	K596A	Pathogenic	0.891
OPA1	O60313-1.3	K596C	Pathogenic	0.975
OPA1	O60313-1.3	K596D	Pathogenic	0.96
OPA1	O60313-1.3	K596E	Pathogenic	0.73
OPA1	O60313-1.3	K596F	Pathogenic	0.958
OPA1	O60313-1.3	K596G	Pathogenic	0.967
OPA1	O60313-1.3	K596H	Pathogenic	0.921
OPA1	O60313-1.3	K596I	Pathogenic	0.956
OPA1	O60313-1.3	K596L	Pathogenic	0.891
OPA1	O60313-1.3	K596M	Pathogenic	0.813
OPA1	O60313-1.3	K596N	Pathogenic	0.878
OPA1	O60313-1.3	K596P	Pathogenic	0.859
OPA1	O60313-1.3	K596Q	Pathogenic	0.653
OPA1	O60313-1.3	K596R	Pathogenic	0.571
OPA1	O60313-1.3	K596S	Pathogenic	0.798
OPA1	O60313-1.3	K596T	Pathogenic	0.904
OPA1	O60313-1.3	K596V	Pathogenic	0.922
OPA1	O60313-1.3	K596W	Pathogenic	0.931
OPA1	O60313-1.3	K596Y	Pathogenic	0.943
OPA1	O60313-1.3	A597C	Pathogenic	0.937
OPA1	O60313-1.3	A597D	Pathogenic	0.988
OPA1	O60313-1.3	A597E	Pathogenic	0.968
OPA1	O60313-1.3	A597F	Pathogenic	0.98
OPA1	O60313-1.3	A597G	Pathogenic	0.954
OPA1	O60313-1.3	A597H	Pathogenic	0.994
OPA1	O60313-1.3	A597I	Pathogenic	0.946
OPA1	O60313-1.3	A597K	Pathogenic	0.953
OPA1	O60313-1.3	A597L	Pathogenic	0.951
OPA1	O60313-1.3	A597M	Pathogenic	0.967
OPA1	O60313-1.3	A597N	Pathogenic	0.99
OPA1	O60313-1.3	A597P	Pathogenic	0.982
OPA1	O60313-1.3	A597Q	Pathogenic	0.978
OPA1	O60313-1.3	A597R	Pathogenic	0.95
OPA1	O60313-1.3	A597S	Pathogenic	0.879
OPA1	O60313-1.3	A597T	Pathogenic	0.962
OPA1	O60313-1.3	A597V	Pathogenic	0.917
OPA1	O60313-1.3	A597W	Pathogenic	0.988
OPA1	O60313-1.3	A597Y	Pathogenic	0.99
OPA1	O60313-1.3	K598A	Pathogenic	0.773
OPA1	O60313-1.3	K598C	Pathogenic	0.943
OPA1	O60313-1.3	K598D	Pathogenic	0.909
OPA1	O60313-1.3	K598E	Pathogenic	0.53
OPA1	O60313-1.3	K598F	Pathogenic	0.905
OPA1	O60313-1.3	K598G	Pathogenic	0.924
OPA1	O60313-1.3	K598H	Pathogenic	0.829
OPA1	O60313-1.3	K598I	Pathogenic	0.9
OPA1	O60313-1.3	K598L	Pathogenic	0.773
OPA1	O60313-1.3	K598M	Pathogenic	0.644
OPA1	O60313-1.3	K598N	Pathogenic	0.751
OPA1	O60313-1.3	K598P	Pathogenic	0.718
OPA1	O60313-1.3	K598Q	Neutral	0.439
OPA1	O60313-1.3	K598R	Neutral	0.357
OPA1	O60313-1.3	K598S	Pathogenic	0.622
OPA1	O60313-1.3	K598T	Pathogenic	0.797
OPA1	O60313-1.3	K598V	Pathogenic	0.832
OPA1	O60313-1.3	K598W	Pathogenic	0.849
OPA1	O60313-1.3	K598Y	Pathogenic	0.873
OPA1	O60313-1.3	N599A	Pathogenic	0.96
OPA1	O60313-1.3	N599C	Pathogenic	0.976
OPA1	O60313-1.3	N599D	Pathogenic	0.677
OPA1	O60313-1.3	N599E	Pathogenic	0.87
OPA1	O60313-1.3	N599F	Pathogenic	0.945
OPA1	O60313-1.3	N599G	Pathogenic	0.777
OPA1	O60313-1.3	N599H	Pathogenic	0.54
OPA1	O60313-1.3	N599I	Pathogenic	0.946
OPA1	O60313-1.3	N599K	Pathogenic	0.814
OPA1	O60313-1.3	N599L	Pathogenic	0.951
OPA1	O60313-1.3	N599M	Pathogenic	0.911
OPA1	O60313-1.3	N599P	Pathogenic	0.947
OPA1	O60313-1.3	N599Q	Pathogenic	0.827
OPA1	O60313-1.3	N599R	Pathogenic	0.805
OPA1	O60313-1.3	N599S	Pathogenic	0.577
OPA1	O60313-1.3	N599T	Pathogenic	0.765
OPA1	O60313-1.3	N599V	Pathogenic	0.97
OPA1	O60313-1.3	N599W	Pathogenic	0.967
OPA1	O60313-1.3	N599Y	Pathogenic	0.925
OPA1	O60313-1.3	E600A	Pathogenic	0.982
OPA1	O60313-1.3	E600C	Pathogenic	0.999
OPA1	O60313-1.3	E600D	Pathogenic	0.838
OPA1	O60313-1.3	E600F	Pathogenic	0.992
OPA1	O60313-1.3	E600G	Pathogenic	0.995
OPA1	O60313-1.3	E600H	Pathogenic	0.962
OPA1	O60313-1.3	E600I	Pathogenic	0.992
OPA1	O60313-1.3	E600K	Pathogenic	0.922
OPA1	O60313-1.3	E600L	Pathogenic	0.993
OPA1	O60313-1.3	E600M	Pathogenic	0.987
OPA1	O60313-1.3	E600N	Pathogenic	0.98
OPA1	O60313-1.3	E600P	Pathogenic	0.976
OPA1	O60313-1.3	E600Q	Pathogenic	0.807
OPA1	O60313-1.3	E600R	Pathogenic	0.97
OPA1	O60313-1.3	E600S	Pathogenic	0.963
OPA1	O60313-1.3	E600T	Pathogenic	0.984
OPA1	O60313-1.3	E600V	Pathogenic	0.988
OPA1	O60313-1.3	E600W	Pathogenic	0.987
OPA1	O60313-1.3	E600Y	Pathogenic	0.989
OPA1	O60313-1.3	I601A	Pathogenic	0.951
OPA1	O60313-1.3	I601C	Pathogenic	0.975
OPA1	O60313-1.3	I601D	Pathogenic	0.985
OPA1	O60313-1.3	I601E	Pathogenic	0.988
OPA1	O60313-1.3	I601F	Pathogenic	0.968
OPA1	O60313-1.3	I601G	Pathogenic	0.997
OPA1	O60313-1.3	I601H	Pathogenic	0.994
OPA1	O60313-1.3	I601K	Pathogenic	0.983
OPA1	O60313-1.3	I601L	Pathogenic	0.778
OPA1	O60313-1.3	I601M	Pathogenic	0.869
OPA1	O60313-1.3	I601N	Pathogenic	0.987
OPA1	O60313-1.3	I601P	Pathogenic	0.996
OPA1	O60313-1.3	I601Q	Pathogenic	0.992
OPA1	O60313-1.3	I601R	Pathogenic	0.982
OPA1	O60313-1.3	I601S	Pathogenic	0.977
OPA1	O60313-1.3	I601T	Pathogenic	0.953
OPA1	O60313-1.3	I601V	Neutral	0.42
OPA1	O60313-1.3	I601W	Pathogenic	0.998
OPA1	O60313-1.3	I601Y	Pathogenic	0.976
OPA1	O60313-1.3	L602A	Pathogenic	0.974
OPA1	O60313-1.3	L602C	Pathogenic	0.987
OPA1	O60313-1.3	L602D	Pathogenic	0.997
OPA1	O60313-1.3	L602E	Pathogenic	0.994
OPA1	O60313-1.3	L602F	Pathogenic	0.981
OPA1	O60313-1.3	L602G	Pathogenic	0.998
OPA1	O60313-1.3	L602H	Pathogenic	0.997
OPA1	O60313-1.3	L602I	Pathogenic	0.86
OPA1	O60313-1.3	L602K	Pathogenic	0.975
OPA1	O60313-1.3	L602M	Pathogenic	0.815
OPA1	O60313-1.3	L602N	Pathogenic	0.993
OPA1	O60313-1.3	L602P	Pathogenic	0.998
OPA1	O60313-1.3	L602Q	Pathogenic	0.988
OPA1	O60313-1.3	L602R	Pathogenic	0.973
OPA1	O60313-1.3	L602S	Pathogenic	0.988
OPA1	O60313-1.3	L602T	Pathogenic	0.975
OPA1	O60313-1.3	L602V	Pathogenic	0.921
OPA1	O60313-1.3	L602W	Pathogenic	0.996
OPA1	O60313-1.3	L602Y	Pathogenic	0.987
OPA1	O60313-1.3	D603A	Pathogenic	0.996
OPA1	O60313-1.3	D603C	Pathogenic	0.998
OPA1	O60313-1.3	D603E	Pathogenic	0.9
OPA1	O60313-1.3	D603F	Pathogenic	0.995
OPA1	O60313-1.3	D603G	Pathogenic	0.991
OPA1	O60313-1.3	D603H	Pathogenic	0.991
OPA1	O60313-1.3	D603I	Pathogenic	0.995
OPA1	O60313-1.3	D603K	Pathogenic	0.995
OPA1	O60313-1.3	D603L	Pathogenic	0.998
OPA1	O60313-1.3	D603M	Pathogenic	0.997
OPA1	O60313-1.3	D603N	Pathogenic	0.964
OPA1	O60313-1.3	D603P	Pathogenic	0.985
OPA1	O60313-1.3	D603Q	Pathogenic	0.981
OPA1	O60313-1.3	D603R	Pathogenic	0.998
OPA1	O60313-1.3	D603S	Pathogenic	0.978
OPA1	O60313-1.3	D603T	Pathogenic	0.99
OPA1	O60313-1.3	D603V	Pathogenic	0.997
OPA1	O60313-1.3	D603W	Pathogenic	0.997
OPA1	O60313-1.3	D603Y	Pathogenic	0.997
OPA1	O60313-1.3	E604A	Pathogenic	0.982
OPA1	O60313-1.3	E604C	Pathogenic	0.999
OPA1	O60313-1.3	E604D	Pathogenic	0.838
OPA1	O60313-1.3	E604F	Pathogenic	0.992
OPA1	O60313-1.3	E604G	Pathogenic	0.995
OPA1	O60313-1.3	E604H	Pathogenic	0.962
OPA1	O60313-1.3	E604I	Pathogenic	0.992
OPA1	O60313-1.3	E604K	Pathogenic	0.922
OPA1	O60313-1.3	E604L	Pathogenic	0.993
OPA1	O60313-1.3	E604M	Pathogenic	0.987
OPA1	O60313-1.3	E604N	Pathogenic	0.98
OPA1	O60313-1.3	E604P	Pathogenic	0.976
OPA1	O60313-1.3	E604Q	Pathogenic	0.807
OPA1	O60313-1.3	E604R	Pathogenic	0.97
OPA1	O60313-1.3	E604S	Pathogenic	0.963
OPA1	O60313-1.3	E604T	Pathogenic	0.984
OPA1	O60313-1.3	E604V	Pathogenic	0.988
OPA1	O60313-1.3	E604W	Pathogenic	0.987
OPA1	O60313-1.3	E604Y	Pathogenic	0.989
OPA1	O60313-1.3	V605A	Pathogenic	0.742
OPA1	O60313-1.3	V605C	Pathogenic	0.943
OPA1	O60313-1.3	V605D	Pathogenic	0.966
OPA1	O60313-1.3	V605E	Pathogenic	0.92
OPA1	O60313-1.3	V605F	Pathogenic	0.921
OPA1	O60313-1.3	V605G	Pathogenic	0.98
OPA1	O60313-1.3	V605H	Pathogenic	0.985
OPA1	O60313-1.3	V605I	Neutral	0.145
OPA1	O60313-1.3	V605K	Pathogenic	0.884
OPA1	O60313-1.3	V605L	Pathogenic	0.611
OPA1	O60313-1.3	V605M	Pathogenic	0.707
OPA1	O60313-1.3	V605N	Pathogenic	0.971
OPA1	O60313-1.3	V605P	Pathogenic	0.975
OPA1	O60313-1.3	V605Q	Pathogenic	0.943
OPA1	O60313-1.3	V605R	Pathogenic	0.954
OPA1	O60313-1.3	V605S	Pathogenic	0.947
OPA1	O60313-1.3	V605T	Pathogenic	0.751
OPA1	O60313-1.3	V605W	Pathogenic	0.983
OPA1	O60313-1.3	V605Y	Pathogenic	0.938
OPA1	O60313-1.3	I606A	Pathogenic	0.674
OPA1	O60313-1.3	I606C	Pathogenic	0.804
OPA1	O60313-1.3	I606D	Pathogenic	0.876
OPA1	O60313-1.3	I606E	Pathogenic	0.895
OPA1	O60313-1.3	I606F	Pathogenic	0.766
OPA1	O60313-1.3	I606G	Pathogenic	0.973
OPA1	O60313-1.3	I606H	Pathogenic	0.947
OPA1	O60313-1.3	I606K	Pathogenic	0.863
OPA1	O60313-1.3	I606L	Neutral	0.273
OPA1	O60313-1.3	I606M	Neutral	0.415
OPA1	O60313-1.3	I606N	Pathogenic	0.894
OPA1	O60313-1.3	I606P	Pathogenic	0.965
OPA1	O60313-1.3	I606Q	Pathogenic	0.927
OPA1	O60313-1.3	I606R	Pathogenic	0.855
OPA1	O60313-1.3	I606S	Pathogenic	0.817
OPA1	O60313-1.3	I606T	Pathogenic	0.685
OPA1	O60313-1.3	I606V	Neutral	0.072
OPA1	O60313-1.3	I606W	Pathogenic	0.98
OPA1	O60313-1.3	I606Y	Pathogenic	0.813
OPA1	O60313-1.3	S607A	Neutral	0.341
OPA1	O60313-1.3	S607C	Pathogenic	0.696
OPA1	O60313-1.3	S607D	Pathogenic	0.502
OPA1	O60313-1.3	S607E	Pathogenic	0.515
OPA1	O60313-1.3	S607F	Pathogenic	0.725
OPA1	O60313-1.3	S607G	Pathogenic	0.65
OPA1	O60313-1.3	S607H	Pathogenic	0.816
OPA1	O60313-1.3	S607I	Pathogenic	0.731
OPA1	O60313-1.3	S607K	Neutral	0.411
OPA1	O60313-1.3	S607L	Pathogenic	0.749
OPA1	O60313-1.3	S607M	Pathogenic	0.613
OPA1	O60313-1.3	S607N	Neutral	0.285
OPA1	O60313-1.3	S607P	Pathogenic	0.742
OPA1	O60313-1.3	S607Q	Pathogenic	0.604
OPA1	O60313-1.3	S607R	Pathogenic	0.656
OPA1	O60313-1.3	S607T	Neutral	0.34
OPA1	O60313-1.3	S607V	Pathogenic	0.833
OPA1	O60313-1.3	S607W	Pathogenic	0.819
OPA1	O60313-1.3	S607Y	Pathogenic	0.846
OPA1	O60313-1.3	L608A	Pathogenic	0.961
OPA1	O60313-1.3	L608C	Pathogenic	0.98
OPA1	O60313-1.3	L608D	Pathogenic	0.996
OPA1	O60313-1.3	L608E	Pathogenic	0.99
OPA1	O60313-1.3	L608F	Pathogenic	0.971
OPA1	O60313-1.3	L608G	Pathogenic	0.998
OPA1	O60313-1.3	L608H	Pathogenic	0.995
OPA1	O60313-1.3	L608I	Pathogenic	0.805
OPA1	O60313-1.3	L608K	Pathogenic	0.963
OPA1	O60313-1.3	L608M	Pathogenic	0.746
OPA1	O60313-1.3	L608N	Pathogenic	0.99
OPA1	O60313-1.3	L608P	Pathogenic	0.997
OPA1	O60313-1.3	L608Q	Pathogenic	0.982
OPA1	O60313-1.3	L608R	Pathogenic	0.961
OPA1	O60313-1.3	L608S	Pathogenic	0.982
OPA1	O60313-1.3	L608T	Pathogenic	0.963
OPA1	O60313-1.3	L608V	Pathogenic	0.887
OPA1	O60313-1.3	L608W	Pathogenic	0.994
OPA1	O60313-1.3	L608Y	Pathogenic	0.981
OPA1	O60313-1.3	S609A	Pathogenic	0.515
OPA1	O60313-1.3	S609C	Pathogenic	0.824
OPA1	O60313-1.3	S609D	Pathogenic	0.674
OPA1	O60313-1.3	S609E	Pathogenic	0.685
OPA1	O60313-1.3	S609F	Pathogenic	0.844
OPA1	O60313-1.3	S609G	Pathogenic	0.792
OPA1	O60313-1.3	S609H	Pathogenic	0.901
OPA1	O60313-1.3	S609I	Pathogenic	0.848
OPA1	O60313-1.3	S609K	Pathogenic	0.589
OPA1	O60313-1.3	S609L	Pathogenic	0.859
OPA1	O60313-1.3	S609M	Pathogenic	0.764
OPA1	O60313-1.3	S609N	Neutral	0.449
OPA1	O60313-1.3	S609P	Pathogenic	0.855
OPA1	O60313-1.3	S609Q	Pathogenic	0.758
OPA1	O60313-1.3	S609R	Pathogenic	0.796
OPA1	O60313-1.3	S609T	Pathogenic	0.514
OPA1	O60313-1.3	S609V	Pathogenic	0.911
OPA1	O60313-1.3	S609W	Pathogenic	0.903
OPA1	O60313-1.3	S609Y	Pathogenic	0.919
OPA1	O60313-1.3	Q610A	Pathogenic	0.987
OPA1	O60313-1.3	Q610C	Pathogenic	0.997
OPA1	O60313-1.3	Q610D	Pathogenic	0.966
OPA1	O60313-1.3	Q610E	Pathogenic	0.801
OPA1	O60313-1.3	Q610F	Pathogenic	0.995
OPA1	O60313-1.3	Q610G	Pathogenic	0.996
OPA1	O60313-1.3	Q610H	Pathogenic	0.973
OPA1	O60313-1.3	Q610I	Pathogenic	0.995
OPA1	O60313-1.3	Q610K	Pathogenic	0.889
OPA1	O60313-1.3	Q610L	Pathogenic	0.986
OPA1	O60313-1.3	Q610M	Pathogenic	0.928
OPA1	O60313-1.3	Q610N	Pathogenic	0.971
OPA1	O60313-1.3	Q610P	Pathogenic	0.983
OPA1	O60313-1.3	Q610R	Pathogenic	0.882
OPA1	O60313-1.3	Q610S	Pathogenic	0.973
OPA1	O60313-1.3	Q610T	Pathogenic	0.989
OPA1	O60313-1.3	Q610V	Pathogenic	0.991
OPA1	O60313-1.3	Q610W	Pathogenic	0.974
OPA1	O60313-1.3	Q610Y	Pathogenic	0.978
OPA1	O60313-1.3	V611A	Pathogenic	0.773
OPA1	O60313-1.3	V611C	Pathogenic	0.951
OPA1	O60313-1.3	V611D	Pathogenic	0.971
OPA1	O60313-1.3	V611E	Pathogenic	0.932
OPA1	O60313-1.3	V611F	Pathogenic	0.933
OPA1	O60313-1.3	V611G	Pathogenic	0.983
OPA1	O60313-1.3	V611H	Pathogenic	0.987
OPA1	O60313-1.3	V611I	Neutral	0.167
OPA1	O60313-1.3	V611K	Pathogenic	0.9
OPA1	O60313-1.3	V611L	Pathogenic	0.65
OPA1	O60313-1.3	V611M	Pathogenic	0.74
OPA1	O60313-1.3	V611N	Pathogenic	0.976
OPA1	O60313-1.3	V611P	Pathogenic	0.978
OPA1	O60313-1.3	V611Q	Pathogenic	0.952
OPA1	O60313-1.3	V611R	Pathogenic	0.961
OPA1	O60313-1.3	V611S	Pathogenic	0.955
OPA1	O60313-1.3	V611T	Pathogenic	0.781
OPA1	O60313-1.3	V611W	Pathogenic	0.986
OPA1	O60313-1.3	V611Y	Pathogenic	0.947
OPA1	O60313-1.3	T612A	Pathogenic	0.798
OPA1	O60313-1.3	T612C	Pathogenic	0.869
OPA1	O60313-1.3	T612D	Pathogenic	0.837
OPA1	O60313-1.3	T612E	Pathogenic	0.846
OPA1	O60313-1.3	T612F	Pathogenic	0.889
OPA1	O60313-1.3	T612G	Pathogenic	0.962
OPA1	O60313-1.3	T612H	Pathogenic	0.969
OPA1	O60313-1.3	T612I	Pathogenic	0.74
OPA1	O60313-1.3	T612K	Pathogenic	0.783
OPA1	O60313-1.3	T612L	Pathogenic	0.758
OPA1	O60313-1.3	T612M	Pathogenic	0.828
OPA1	O60313-1.3	T612N	Pathogenic	0.672
OPA1	O60313-1.3	T612P	Pathogenic	0.895
OPA1	O60313-1.3	T612Q	Pathogenic	0.887
OPA1	O60313-1.3	T612R	Pathogenic	0.772
OPA1	O60313-1.3	T612S	Pathogenic	0.527
OPA1	O60313-1.3	T612V	Pathogenic	0.644
OPA1	O60313-1.3	T612W	Pathogenic	0.826
OPA1	O60313-1.3	T612Y	Pathogenic	0.944
OPA1	O60313-1.3	P613A	Pathogenic	0.986
OPA1	O60313-1.3	P613C	Pathogenic	0.999
OPA1	O60313-1.3	P613D	Pathogenic	0.966
OPA1	O60313-1.3	P613E	Pathogenic	0.968
OPA1	O60313-1.3	P613F	Pathogenic	0.999
OPA1	O60313-1.3	P613G	Pathogenic	0.993
OPA1	O60313-1.3	P613H	Pathogenic	0.994
OPA1	O60313-1.3	P613I	Pathogenic	0.997
OPA1	O60313-1.3	P613K	Pathogenic	0.952
OPA1	O60313-1.3	P613L	Pathogenic	0.997
OPA1	O60313-1.3	P613M	Pathogenic	0.994
OPA1	O60313-1.3	P613N	Pathogenic	0.99
OPA1	O60313-1.3	P613Q	Pathogenic	0.977
OPA1	O60313-1.3	P613R	Pathogenic	0.982
OPA1	O60313-1.3	P613S	Pathogenic	0.981
OPA1	O60313-1.3	P613T	Pathogenic	0.986
OPA1	O60313-1.3	P613V	Pathogenic	0.995
OPA1	O60313-1.3	P613W	Pathogenic	0.998
OPA1	O60313-1.3	P613Y	Pathogenic	0.998
OPA1	O60313-1.3	K614A	Neutral	0.477
OPA1	O60313-1.3	K614C	Pathogenic	0.816
OPA1	O60313-1.3	K614D	Pathogenic	0.728
OPA1	O60313-1.3	K614E	Neutral	0.232
OPA1	O60313-1.3	K614F	Pathogenic	0.719
OPA1	O60313-1.3	K614G	Pathogenic	0.766
OPA1	O60313-1.3	K614H	Pathogenic	0.565
OPA1	O60313-1.3	K614I	Pathogenic	0.707
OPA1	O60313-1.3	K614L	Neutral	0.478
OPA1	O60313-1.3	K614M	Neutral	0.327
OPA1	O60313-1.3	K614N	Neutral	0.447
OPA1	O60313-1.3	K614P	Neutral	0.406
OPA1	O60313-1.3	K614Q	Neutral	0.174
OPA1	O60313-1.3	K614R	Neutral	0.13
OPA1	O60313-1.3	K614S	Neutral	0.306
OPA1	O60313-1.3	K614T	Pathogenic	0.513
OPA1	O60313-1.3	K614V	Pathogenic	0.571
OPA1	O60313-1.3	K614W	Pathogenic	0.601
OPA1	O60313-1.3	K614Y	Pathogenic	0.648
OPA1	O60313-1.3	H615A	Pathogenic	0.983
OPA1	O60313-1.3	H615C	Pathogenic	0.99
OPA1	O60313-1.3	H615D	Pathogenic	0.916
OPA1	O60313-1.3	H615E	Pathogenic	0.82
OPA1	O60313-1.3	H615F	Pathogenic	0.851
OPA1	O60313-1.3	H615G	Pathogenic	0.982
OPA1	O60313-1.3	H615I	Pathogenic	0.98
OPA1	O60313-1.3	H615K	Pathogenic	0.903
OPA1	O60313-1.3	H615L	Pathogenic	0.982
OPA1	O60313-1.3	H615M	Pathogenic	0.966
OPA1	O60313-1.3	H615N	Pathogenic	0.608
OPA1	O60313-1.3	H615P	Pathogenic	0.977
OPA1	O60313-1.3	H615Q	Pathogenic	0.872
OPA1	O60313-1.3	H615R	Pathogenic	0.751
OPA1	O60313-1.3	H615S	Pathogenic	0.952
OPA1	O60313-1.3	H615T	Pathogenic	0.985
OPA1	O60313-1.3	H615V	Pathogenic	0.988
OPA1	O60313-1.3	H615W	Pathogenic	0.907
OPA1	O60313-1.3	H615Y	Neutral	0.328
OPA1	O60313-1.3	W616A	Pathogenic	0.996
OPA1	O60313-1.3	W616C	Pathogenic	0.994
OPA1	O60313-1.3	W616D	Pathogenic	0.997
OPA1	O60313-1.3	W616E	Pathogenic	0.992
OPA1	O60313-1.3	W616F	Pathogenic	0.947
OPA1	O60313-1.3	W616G	Pathogenic	0.984
OPA1	O60313-1.3	W616H	Pathogenic	0.989
OPA1	O60313-1.3	W616I	Pathogenic	0.999
OPA1	O60313-1.3	W616K	Pathogenic	0.99
OPA1	O60313-1.3	W616L	Pathogenic	0.997
OPA1	O60313-1.3	W616M	Pathogenic	0.988
OPA1	O60313-1.3	W616N	Pathogenic	0.997
OPA1	O60313-1.3	W616P	Pathogenic	0.999
OPA1	O60313-1.3	W616Q	Pathogenic	0.984
OPA1	O60313-1.3	W616R	Pathogenic	0.99
OPA1	O60313-1.3	W616S	Pathogenic	0.995
OPA1	O60313-1.3	W616T	Pathogenic	0.989
OPA1	O60313-1.3	W616V	Pathogenic	0.998
OPA1	O60313-1.3	W616Y	Pathogenic	0.745
OPA1	O60313-1.3	E617A	Pathogenic	0.985
OPA1	O60313-1.3	E617C	Pathogenic	0.999
OPA1	O60313-1.3	E617D	Pathogenic	0.859
OPA1	O60313-1.3	E617F	Pathogenic	0.993
OPA1	O60313-1.3	E617G	Pathogenic	0.996
OPA1	O60313-1.3	E617H	Pathogenic	0.967
OPA1	O60313-1.3	E617I	Pathogenic	0.993
OPA1	O60313-1.3	E617K	Pathogenic	0.933
OPA1	O60313-1.3	E617L	Pathogenic	0.994
OPA1	O60313-1.3	E617M	Pathogenic	0.989
OPA1	O60313-1.3	E617N	Pathogenic	0.983
OPA1	O60313-1.3	E617P	Pathogenic	0.98
OPA1	O60313-1.3	E617Q	Pathogenic	0.831
OPA1	O60313-1.3	E617R	Pathogenic	0.975
OPA1	O60313-1.3	E617S	Pathogenic	0.969
OPA1	O60313-1.3	E617T	Pathogenic	0.987
OPA1	O60313-1.3	E617V	Pathogenic	0.989
OPA1	O60313-1.3	E617W	Pathogenic	0.989
OPA1	O60313-1.3	E617Y	Pathogenic	0.991
OPA1	O60313-1.3	E618A	Pathogenic	0.63
OPA1	O60313-1.3	E618C	Pathogenic	0.96
OPA1	O60313-1.3	E618D	Neutral	0.139
OPA1	O60313-1.3	E618F	Pathogenic	0.797
OPA1	O60313-1.3	E618G	Pathogenic	0.859
OPA1	O60313-1.3	E618H	Neutral	0.438
OPA1	O60313-1.3	E618I	Pathogenic	0.801
OPA1	O60313-1.3	E618K	Neutral	0.27
OPA1	O60313-1.3	E618L	Pathogenic	0.816
OPA1	O60313-1.3	E618M	Pathogenic	0.701
OPA1	O60313-1.3	E618N	Pathogenic	0.601
OPA1	O60313-1.3	E618P	Pathogenic	0.56
OPA1	O60313-1.3	E618Q	Neutral	0.115
OPA1	O60313-1.3	E618R	Pathogenic	0.502
OPA1	O60313-1.3	E618S	Neutral	0.452
OPA1	O60313-1.3	E618T	Pathogenic	0.663
OPA1	O60313-1.3	E618V	Pathogenic	0.712
OPA1	O60313-1.3	E618W	Pathogenic	0.698
OPA1	O60313-1.3	E618Y	Pathogenic	0.738
OPA1	O60313-1.3	I619A	Neutral	0.46
OPA1	O60313-1.3	I619C	Pathogenic	0.629
OPA1	O60313-1.3	I619D	Pathogenic	0.745
OPA1	O60313-1.3	I619E	Pathogenic	0.779
OPA1	O60313-1.3	I619F	Pathogenic	0.575
OPA1	O60313-1.3	I619G	Pathogenic	0.936
OPA1	O60313-1.3	I619H	Pathogenic	0.881
OPA1	O60313-1.3	I619K	Pathogenic	0.722
OPA1	O60313-1.3	I619L	Neutral	0.134
OPA1	O60313-1.3	I619M	Neutral	0.226
OPA1	O60313-1.3	I619N	Pathogenic	0.776
OPA1	O60313-1.3	I619P	Pathogenic	0.919
OPA1	O60313-1.3	I619Q	Pathogenic	0.84
OPA1	O60313-1.3	I619R	Pathogenic	0.709
OPA1	O60313-1.3	I619S	Pathogenic	0.648
OPA1	O60313-1.3	I619T	Neutral	0.473
OPA1	O60313-1.3	I619V	Neutral	0.031
OPA1	O60313-1.3	I619W	Pathogenic	0.952
OPA1	O60313-1.3	I619Y	Pathogenic	0.643
OPA1	O60313-1.3	L620A	Pathogenic	0.971
OPA1	O60313-1.3	L620C	Pathogenic	0.985
OPA1	O60313-1.3	L620D	Pathogenic	0.997
OPA1	O60313-1.3	L620E	Pathogenic	0.993
OPA1	O60313-1.3	L620F	Pathogenic	0.978
OPA1	O60313-1.3	L620G	Pathogenic	0.998
OPA1	O60313-1.3	L620H	Pathogenic	0.997
OPA1	O60313-1.3	L620I	Pathogenic	0.847
OPA1	O60313-1.3	L620K	Pathogenic	0.972
OPA1	O60313-1.3	L620M	Pathogenic	0.799
OPA1	O60313-1.3	L620N	Pathogenic	0.993
OPA1	O60313-1.3	L620P	Pathogenic	0.998
OPA1	O60313-1.3	L620Q	Pathogenic	0.986
OPA1	O60313-1.3	L620R	Pathogenic	0.971
OPA1	O60313-1.3	L620S	Pathogenic	0.986
OPA1	O60313-1.3	L620T	Pathogenic	0.972
OPA1	O60313-1.3	L620V	Pathogenic	0.914
OPA1	O60313-1.3	L620W	Pathogenic	0.996
OPA1	O60313-1.3	L620Y	Pathogenic	0.986
OPA1	O60313-1.3	Q621A	Neutral	0.442
OPA1	O60313-1.3	Q621C	Pathogenic	0.794
OPA1	O60313-1.3	Q621D	Neutral	0.227
OPA1	O60313-1.3	Q621E	Neutral	0.04
OPA1	O60313-1.3	Q621F	Pathogenic	0.654
OPA1	O60313-1.3	Q621G	Pathogenic	0.739
OPA1	O60313-1.3	Q621H	Neutral	0.274
OPA1	O60313-1.3	Q621I	Pathogenic	0.661
OPA1	O60313-1.3	Q621K	Neutral	0.077
OPA1	O60313-1.3	Q621L	Neutral	0.424
OPA1	O60313-1.3	Q621M	Neutral	0.119
OPA1	O60313-1.3	Q621N	Neutral	0.258
OPA1	O60313-1.3	Q621P	Neutral	0.372
OPA1	O60313-1.3	Q621R	Neutral	0.073
OPA1	O60313-1.3	Q621S	Neutral	0.277
OPA1	O60313-1.3	Q621T	Neutral	0.478
OPA1	O60313-1.3	Q621V	Pathogenic	0.535
OPA1	O60313-1.3	Q621W	Neutral	0.278
OPA1	O60313-1.3	Q621Y	Neutral	0.32
OPA1	O60313-1.3	Q622A	Neutral	0.031
OPA1	O60313-1.3	Q622C	Neutral	0.135
OPA1	O60313-1.3	Q622D	Neutral	0.012
OPA1	O60313-1.3	Q622E	Neutral	0.002
OPA1	O60313-1.3	Q622F	Neutral	0.071
OPA1	O60313-1.3	Q622G	Neutral	0.103
OPA1	O60313-1.3	Q622H	Neutral	0.015
OPA1	O60313-1.3	Q622I	Neutral	0.073
OPA1	O60313-1.3	Q622K	Neutral	0.003
OPA1	O60313-1.3	Q622L	Neutral	0.029
OPA1	O60313-1.3	Q622M	Neutral	0.005
OPA1	O60313-1.3	Q622N	Neutral	0.014
OPA1	O60313-1.3	Q622P	Neutral	0.023
OPA1	O60313-1.3	Q622R	Neutral	0.003
OPA1	O60313-1.3	Q622S	Neutral	0.015
OPA1	O60313-1.3	Q622T	Neutral	0.036
OPA1	O60313-1.3	Q622V	Neutral	0.044
OPA1	O60313-1.3	Q622W	Neutral	0.015
OPA1	O60313-1.3	Q622Y	Neutral	0.019
OPA1	O60313-1.3	S623A	Neutral	0.004
OPA1	O60313-1.3	S623C	Neutral	0.016
OPA1	O60313-1.3	S623D	Neutral	0.007
OPA1	O60313-1.3	S623E	Neutral	0.008
OPA1	O60313-1.3	S623F	Neutral	0.019
OPA1	O60313-1.3	S623G	Neutral	0.013
OPA1	O60313-1.3	S623H	Neutral	0.031
OPA1	O60313-1.3	S623I	Neutral	0.019
OPA1	O60313-1.3	S623K	Neutral	0.005
OPA1	O60313-1.3	S623L	Neutral	0.021
OPA1	O60313-1.3	S623M	Neutral	0.011
OPA1	O60313-1.3	S623N	Neutral	0.003
OPA1	O60313-1.3	S623P	Neutral	0.02
OPA1	O60313-1.3	S623Q	Neutral	0.011
OPA1	O60313-1.3	S623R	Neutral	0.013
OPA1	O60313-1.3	S623T	Neutral	0.004
OPA1	O60313-1.3	S623V	Neutral	0.034
OPA1	O60313-1.3	S623W	Neutral	0.031
OPA1	O60313-1.3	S623Y	Neutral	0.038
OPA1	O60313-1.3	L624A	Pathogenic	0.723
OPA1	O60313-1.3	L624C	Pathogenic	0.838
OPA1	O60313-1.3	L624D	Pathogenic	0.963
OPA1	O60313-1.3	L624E	Pathogenic	0.915
OPA1	O60313-1.3	L624F	Pathogenic	0.779
OPA1	O60313-1.3	L624G	Pathogenic	0.978
OPA1	O60313-1.3	L624H	Pathogenic	0.958
OPA1	O60313-1.3	L624I	Neutral	0.301
OPA1	O60313-1.3	L624K	Pathogenic	0.732
OPA1	O60313-1.3	L624M	Neutral	0.235
OPA1	O60313-1.3	L624N	Pathogenic	0.914
OPA1	O60313-1.3	L624P	Pathogenic	0.972
OPA1	O60313-1.3	L624Q	Pathogenic	0.847
OPA1	O60313-1.3	L624R	Pathogenic	0.72
OPA1	O60313-1.3	L624S	Pathogenic	0.849
OPA1	O60313-1.3	L624T	Pathogenic	0.733
OPA1	O60313-1.3	L624V	Neutral	0.451
OPA1	O60313-1.3	L624W	Pathogenic	0.946
OPA1	O60313-1.3	L624Y	Pathogenic	0.846
OPA1	O60313-1.3	W625A	Pathogenic	0.997
OPA1	O60313-1.3	W625C	Pathogenic	0.996
OPA1	O60313-1.3	W625D	Pathogenic	0.998
OPA1	O60313-1.3	W625E	Pathogenic	0.994
OPA1	O60313-1.3	W625F	Pathogenic	0.963
OPA1	O60313-1.3	W625G	Pathogenic	0.989
OPA1	O60313-1.3	W625H	Pathogenic	0.992
OPA1	O60313-1.3	W625I	Pathogenic	0.999
OPA1	O60313-1.3	W625K	Pathogenic	0.993
OPA1	O60313-1.3	W625L	Pathogenic	0.998
OPA1	O60313-1.3	W625M	Pathogenic	0.992
OPA1	O60313-1.3	W625N	Pathogenic	0.998
OPA1	O60313-1.3	W625P	Pathogenic	0.999
OPA1	O60313-1.3	W625Q	Pathogenic	0.989
OPA1	O60313-1.3	W625R	Pathogenic	0.993
OPA1	O60313-1.3	W625S	Pathogenic	0.996
OPA1	O60313-1.3	W625T	Pathogenic	0.992
OPA1	O60313-1.3	W625V	Pathogenic	0.999
OPA1	O60313-1.3	W625Y	Pathogenic	0.81
OPA1	O60313-1.3	E626A	Pathogenic	0.797
OPA1	O60313-1.3	E626C	Pathogenic	0.982
OPA1	O60313-1.3	E626D	Neutral	0.271
OPA1	O60313-1.3	E626F	Pathogenic	0.901
OPA1	O60313-1.3	E626G	Pathogenic	0.934
OPA1	O60313-1.3	E626H	Pathogenic	0.643
OPA1	O60313-1.3	E626I	Pathogenic	0.903
OPA1	O60313-1.3	E626K	Neutral	0.461
OPA1	O60313-1.3	E626L	Pathogenic	0.911
OPA1	O60313-1.3	E626M	Pathogenic	0.844
OPA1	O60313-1.3	E626N	Pathogenic	0.777
OPA1	O60313-1.3	E626P	Pathogenic	0.747
OPA1	O60313-1.3	E626Q	Neutral	0.231
OPA1	O60313-1.3	E626R	Pathogenic	0.7
OPA1	O60313-1.3	E626S	Pathogenic	0.656
OPA1	O60313-1.3	E626T	Pathogenic	0.82
OPA1	O60313-1.3	E626V	Pathogenic	0.851
OPA1	O60313-1.3	E626W	Pathogenic	0.842
OPA1	O60313-1.3	E626Y	Pathogenic	0.867
OPA1	O60313-1.3	R627A	Pathogenic	0.62
OPA1	O60313-1.3	R627C	Pathogenic	0.888
OPA1	O60313-1.3	R627D	Pathogenic	0.933
OPA1	O60313-1.3	R627E	Pathogenic	0.61
OPA1	O60313-1.3	R627F	Pathogenic	0.82
OPA1	O60313-1.3	R627G	Pathogenic	0.854
OPA1	O60313-1.3	R627H	Neutral	0.445
OPA1	O60313-1.3	R627I	Pathogenic	0.812
OPA1	O60313-1.3	R627K	Neutral	0.221
OPA1	O60313-1.3	R627L	Pathogenic	0.621
OPA1	O60313-1.3	R627M	Neutral	0.464
OPA1	O60313-1.3	R627N	Pathogenic	0.591
OPA1	O60313-1.3	R627P	Pathogenic	0.78
OPA1	O60313-1.3	R627Q	Neutral	0.273
OPA1	O60313-1.3	R627S	Pathogenic	0.696
OPA1	O60313-1.3	R627T	Pathogenic	0.653
OPA1	O60313-1.3	R627V	Pathogenic	0.873
OPA1	O60313-1.3	R627W	Pathogenic	0.748
OPA1	O60313-1.3	R627Y	Pathogenic	0.774
OPA1	O60313-1.3	V628A	Pathogenic	0.697
OPA1	O60313-1.3	V628C	Pathogenic	0.93
OPA1	O60313-1.3	V628D	Pathogenic	0.958
OPA1	O60313-1.3	V628E	Pathogenic	0.902
OPA1	O60313-1.3	V628F	Pathogenic	0.903
OPA1	O60313-1.3	V628G	Pathogenic	0.975
OPA1	O60313-1.3	V628H	Pathogenic	0.981
OPA1	O60313-1.3	V628I	Neutral	0.12
OPA1	O60313-1.3	V628K	Pathogenic	0.859
OPA1	O60313-1.3	V628L	Pathogenic	0.557
OPA1	O60313-1.3	V628M	Pathogenic	0.659
OPA1	O60313-1.3	V628N	Pathogenic	0.964
OPA1	O60313-1.3	V628P	Pathogenic	0.968
OPA1	O60313-1.3	V628Q	Pathogenic	0.93
OPA1	O60313-1.3	V628R	Pathogenic	0.943
OPA1	O60313-1.3	V628S	Pathogenic	0.935
OPA1	O60313-1.3	V628T	Pathogenic	0.707
OPA1	O60313-1.3	V628W	Pathogenic	0.979
OPA1	O60313-1.3	V628Y	Pathogenic	0.924
OPA1	O60313-1.3	S629A	Pathogenic	0.859
OPA1	O60313-1.3	S629C	Pathogenic	0.964
OPA1	O60313-1.3	S629D	Pathogenic	0.922
OPA1	O60313-1.3	S629E	Pathogenic	0.926
OPA1	O60313-1.3	S629F	Pathogenic	0.969
OPA1	O60313-1.3	S629G	Pathogenic	0.956
OPA1	O60313-1.3	S629H	Pathogenic	0.981
OPA1	O60313-1.3	S629I	Pathogenic	0.97
OPA1	O60313-1.3	S629K	Pathogenic	0.891
OPA1	O60313-1.3	S629L	Pathogenic	0.972
OPA1	O60313-1.3	S629M	Pathogenic	0.949
OPA1	O60313-1.3	S629N	Pathogenic	0.823
OPA1	O60313-1.3	S629P	Pathogenic	0.971
OPA1	O60313-1.3	S629Q	Pathogenic	0.947
OPA1	O60313-1.3	S629R	Pathogenic	0.957
OPA1	O60313-1.3	S629T	Pathogenic	0.858
OPA1	O60313-1.3	S629V	Pathogenic	0.983
OPA1	O60313-1.3	S629W	Pathogenic	0.981
OPA1	O60313-1.3	S629Y	Pathogenic	0.985
OPA1	O60313-1.3	T630A	Pathogenic	0.551
OPA1	O60313-1.3	T630C	Pathogenic	0.673
OPA1	O60313-1.3	T630D	Pathogenic	0.615
OPA1	O60313-1.3	T630E	Pathogenic	0.631
OPA1	O60313-1.3	T630F	Pathogenic	0.715
OPA1	O60313-1.3	T630G	Pathogenic	0.888
OPA1	O60313-1.3	T630H	Pathogenic	0.906
OPA1	O60313-1.3	T630I	Neutral	0.47
OPA1	O60313-1.3	T630K	Pathogenic	0.529
OPA1	O60313-1.3	T630L	Neutral	0.494
OPA1	O60313-1.3	T630M	Pathogenic	0.6
OPA1	O60313-1.3	T630N	Neutral	0.39
OPA1	O60313-1.3	T630P	Pathogenic	0.727
OPA1	O60313-1.3	T630Q	Pathogenic	0.711
OPA1	O60313-1.3	T630R	Pathogenic	0.513
OPA1	O60313-1.3	T630S	Neutral	0.258
OPA1	O60313-1.3	T630V	Neutral	0.36
OPA1	O60313-1.3	T630W	Pathogenic	0.597
OPA1	O60313-1.3	T630Y	Pathogenic	0.839
OPA1	O60313-1.3	H631A	Pathogenic	0.991
OPA1	O60313-1.3	H631C	Pathogenic	0.994
OPA1	O60313-1.3	H631D	Pathogenic	0.953
OPA1	O60313-1.3	H631E	Pathogenic	0.895
OPA1	O60313-1.3	H631F	Pathogenic	0.914
OPA1	O60313-1.3	H631G	Pathogenic	0.99
OPA1	O60313-1.3	H631I	Pathogenic	0.989
OPA1	O60313-1.3	H631K	Pathogenic	0.945
OPA1	O60313-1.3	H631L	Pathogenic	0.99
OPA1	O60313-1.3	H631M	Pathogenic	0.982
OPA1	O60313-1.3	H631N	Pathogenic	0.743
OPA1	O60313-1.3	H631P	Pathogenic	0.987
OPA1	O60313-1.3	H631Q	Pathogenic	0.927
OPA1	O60313-1.3	H631R	Pathogenic	0.849
OPA1	O60313-1.3	H631S	Pathogenic	0.974
OPA1	O60313-1.3	H631T	Pathogenic	0.992
OPA1	O60313-1.3	H631V	Pathogenic	0.993
OPA1	O60313-1.3	H631W	Pathogenic	0.948
OPA1	O60313-1.3	H631Y	Neutral	0.476
OPA1	O60313-1.3	V632A	Pathogenic	0.957
OPA1	O60313-1.3	V632C	Pathogenic	0.992
OPA1	O60313-1.3	V632D	Pathogenic	0.996
OPA1	O60313-1.3	V632E	Pathogenic	0.989
OPA1	O60313-1.3	V632F	Pathogenic	0.989
OPA1	O60313-1.3	V632G	Pathogenic	0.997
OPA1	O60313-1.3	V632H	Pathogenic	0.998
OPA1	O60313-1.3	V632I	Pathogenic	0.569
OPA1	O60313-1.3	V632K	Pathogenic	0.983
OPA1	O60313-1.3	V632L	Pathogenic	0.924
OPA1	O60313-1.3	V632M	Pathogenic	0.949
OPA1	O60313-1.3	V632N	Pathogenic	0.996
OPA1	O60313-1.3	V632P	Pathogenic	0.997
OPA1	O60313-1.3	V632Q	Pathogenic	0.992
OPA1	O60313-1.3	V632R	Pathogenic	0.994
OPA1	O60313-1.3	V632S	Pathogenic	0.993
OPA1	O60313-1.3	V632T	Pathogenic	0.959
OPA1	O60313-1.3	V632W	Pathogenic	0.998
OPA1	O60313-1.3	V632Y	Pathogenic	0.992
OPA1	O60313-1.3	I633A	Pathogenic	0.631
OPA1	O60313-1.3	I633C	Pathogenic	0.773
OPA1	O60313-1.3	I633D	Pathogenic	0.854
OPA1	O60313-1.3	I633E	Pathogenic	0.876
OPA1	O60313-1.3	I633F	Pathogenic	0.731
OPA1	O60313-1.3	I633G	Pathogenic	0.967
OPA1	O60313-1.3	I633H	Pathogenic	0.937
OPA1	O60313-1.3	I633K	Pathogenic	0.839
OPA1	O60313-1.3	I633L	Neutral	0.237
OPA1	O60313-1.3	I633M	Neutral	0.369
OPA1	O60313-1.3	I633N	Pathogenic	0.874
OPA1	O60313-1.3	I633P	Pathogenic	0.958
OPA1	O60313-1.3	I633Q	Pathogenic	0.913
OPA1	O60313-1.3	I633R	Pathogenic	0.83
OPA1	O60313-1.3	I633S	Pathogenic	0.787
OPA1	O60313-1.3	I633T	Pathogenic	0.642
OPA1	O60313-1.3	I633V	Neutral	0.06
OPA1	O60313-1.3	I633W	Pathogenic	0.976
OPA1	O60313-1.3	I633Y	Pathogenic	0.783
OPA1	O60313-1.3	E634A	Pathogenic	0.975
OPA1	O60313-1.3	E634C	Pathogenic	0.998
OPA1	O60313-1.3	E634D	Pathogenic	0.789
OPA1	O60313-1.3	E634F	Pathogenic	0.989
OPA1	O60313-1.3	E634G	Pathogenic	0.993
OPA1	O60313-1.3	E634H	Pathogenic	0.948
OPA1	O60313-1.3	E634I	Pathogenic	0.989
OPA1	O60313-1.3	E634K	Pathogenic	0.896
OPA1	O60313-1.3	E634L	Pathogenic	0.99
OPA1	O60313-1.3	E634M	Pathogenic	0.982
OPA1	O60313-1.3	E634N	Pathogenic	0.972
OPA1	O60313-1.3	E634P	Pathogenic	0.967
OPA1	O60313-1.3	E634Q	Pathogenic	0.751
OPA1	O60313-1.3	E634R	Pathogenic	0.959
OPA1	O60313-1.3	E634S	Pathogenic	0.95
OPA1	O60313-1.3	E634T	Pathogenic	0.979
OPA1	O60313-1.3	E634V	Pathogenic	0.983
OPA1	O60313-1.3	E634W	Pathogenic	0.982
OPA1	O60313-1.3	E634Y	Pathogenic	0.985
OPA1	O60313-1.3	N635A	Pathogenic	0.99
OPA1	O60313-1.3	N635C	Pathogenic	0.994
OPA1	O60313-1.3	N635D	Pathogenic	0.9
OPA1	O60313-1.3	N635E	Pathogenic	0.966
OPA1	O60313-1.3	N635F	Pathogenic	0.986
OPA1	O60313-1.3	N635G	Pathogenic	0.937
OPA1	O60313-1.3	N635H	Pathogenic	0.834
OPA1	O60313-1.3	N635I	Pathogenic	0.987
OPA1	O60313-1.3	N635K	Pathogenic	0.949
OPA1	O60313-1.3	N635L	Pathogenic	0.988
OPA1	O60313-1.3	N635M	Pathogenic	0.978
OPA1	O60313-1.3	N635P	Pathogenic	0.987
OPA1	O60313-1.3	N635Q	Pathogenic	0.953
OPA1	O60313-1.3	N635R	Pathogenic	0.946
OPA1	O60313-1.3	N635S	Pathogenic	0.853
OPA1	O60313-1.3	N635T	Pathogenic	0.933
OPA1	O60313-1.3	N635V	Pathogenic	0.993
OPA1	O60313-1.3	N635W	Pathogenic	0.992
OPA1	O60313-1.3	N635Y	Pathogenic	0.981
OPA1	O60313-1.3	I636A	Pathogenic	0.976
OPA1	O60313-1.3	I636C	Pathogenic	0.988
OPA1	O60313-1.3	I636D	Pathogenic	0.993
OPA1	O60313-1.3	I636E	Pathogenic	0.994
OPA1	O60313-1.3	I636F	Pathogenic	0.985
OPA1	O60313-1.3	I636G	Pathogenic	0.999
OPA1	O60313-1.3	I636H	Pathogenic	0.997
OPA1	O60313-1.3	I636K	Pathogenic	0.992
OPA1	O60313-1.3	I636L	Pathogenic	0.882
OPA1	O60313-1.3	I636M	Pathogenic	0.934
OPA1	O60313-1.3	I636N	Pathogenic	0.994
OPA1	O60313-1.3	I636P	Pathogenic	0.998
OPA1	O60313-1.3	I636Q	Pathogenic	0.996
OPA1	O60313-1.3	I636R	Pathogenic	0.992
OPA1	O60313-1.3	I636S	Pathogenic	0.989
OPA1	O60313-1.3	I636T	Pathogenic	0.977
OPA1	O60313-1.3	I636V	Pathogenic	0.607
OPA1	O60313-1.3	I636W	Pathogenic	0.999
OPA1	O60313-1.3	I636Y	Pathogenic	0.989
OPA1	O60313-1.3	Y637A	Pathogenic	0.997
OPA1	O60313-1.3	Y637C	Pathogenic	0.999
OPA1	O60313-1.3	Y637D	Pathogenic	0.998
OPA1	O60313-1.3	Y637E	Pathogenic	0.994
OPA1	O60313-1.3	Y637F	Pathogenic	0.652
OPA1	O60313-1.3	Y637G	Pathogenic	0.999
OPA1	O60313-1.3	Y637H	Pathogenic	0.836
OPA1	O60313-1.3	Y637I	Pathogenic	0.992
OPA1	O60313-1.3	Y637K	Pathogenic	0.993
OPA1	O60313-1.3	Y637L	Pathogenic	0.993
OPA1	O60313-1.3	Y637M	Pathogenic	0.995
OPA1	O60313-1.3	Y637N	Pathogenic	0.994
OPA1	O60313-1.3	Y637P	Pathogenic	0.999
OPA1	O60313-1.3	Y637Q	Pathogenic	0.989
OPA1	O60313-1.3	Y637R	Pathogenic	0.993
OPA1	O60313-1.3	Y637S	Pathogenic	0.996
OPA1	O60313-1.3	Y637T	Pathogenic	0.997
OPA1	O60313-1.3	Y637V	Pathogenic	0.995
OPA1	O60313-1.3	Y637W	Pathogenic	0.77
OPA1	O60313-1.3	L638A	Pathogenic	0.972
OPA1	O60313-1.3	L638C	Pathogenic	0.986
OPA1	O60313-1.3	L638D	Pathogenic	0.997
OPA1	O60313-1.3	L638E	Pathogenic	0.993
OPA1	O60313-1.3	L638F	Pathogenic	0.979
OPA1	O60313-1.3	L638G	Pathogenic	0.998
OPA1	O60313-1.3	L638H	Pathogenic	0.997
OPA1	O60313-1.3	L638I	Pathogenic	0.85
OPA1	O60313-1.3	L638K	Pathogenic	0.973
OPA1	O60313-1.3	L638M	Pathogenic	0.802
OPA1	O60313-1.3	L638N	Pathogenic	0.993
OPA1	O60313-1.3	L638P	Pathogenic	0.998
OPA1	O60313-1.3	L638Q	Pathogenic	0.986
OPA1	O60313-1.3	L638R	Pathogenic	0.971
OPA1	O60313-1.3	L638S	Pathogenic	0.987
OPA1	O60313-1.3	L638T	Pathogenic	0.973
OPA1	O60313-1.3	L638V	Pathogenic	0.915
OPA1	O60313-1.3	L638W	Pathogenic	0.996
OPA1	O60313-1.3	L638Y	Pathogenic	0.986
OPA1	O60313-1.3	P639A	Pathogenic	0.996
OPA1	O60313-1.3	P639C	Pathogenic	1.0
OPA1	O60313-1.3	P639D	Pathogenic	0.989
OPA1	O60313-1.3	P639E	Pathogenic	0.99
OPA1	O60313-1.3	P639F	Pathogenic	1.0
OPA1	O60313-1.3	P639G	Pathogenic	0.998
OPA1	O60313-1.3	P639H	Pathogenic	0.998
OPA1	O60313-1.3	P639I	Pathogenic	0.999
OPA1	O60313-1.3	P639K	Pathogenic	0.985
OPA1	O60313-1.3	P639L	Pathogenic	0.999
OPA1	O60313-1.3	P639M	Pathogenic	0.998
OPA1	O60313-1.3	P639N	Pathogenic	0.997
OPA1	O60313-1.3	P639Q	Pathogenic	0.993
OPA1	O60313-1.3	P639R	Pathogenic	0.994
OPA1	O60313-1.3	P639S	Pathogenic	0.994
OPA1	O60313-1.3	P639T	Pathogenic	0.996
OPA1	O60313-1.3	P639V	Pathogenic	0.998
OPA1	O60313-1.3	P639W	Pathogenic	0.999
OPA1	O60313-1.3	P639Y	Pathogenic	1.0
OPA1	O60313-1.3	A640C	Pathogenic	0.982
OPA1	O60313-1.3	A640D	Pathogenic	0.997
OPA1	O60313-1.3	A640E	Pathogenic	0.991
OPA1	O60313-1.3	A640F	Pathogenic	0.995
OPA1	O60313-1.3	A640G	Pathogenic	0.987
OPA1	O60313-1.3	A640H	Pathogenic	0.998
OPA1	O60313-1.3	A640I	Pathogenic	0.985
OPA1	O60313-1.3	A640K	Pathogenic	0.987
OPA1	O60313-1.3	A640L	Pathogenic	0.986
OPA1	O60313-1.3	A640M	Pathogenic	0.991
OPA1	O60313-1.3	A640N	Pathogenic	0.997
OPA1	O60313-1.3	A640P	Pathogenic	0.995
OPA1	O60313-1.3	A640Q	Pathogenic	0.994
OPA1	O60313-1.3	A640R	Pathogenic	0.986
OPA1	O60313-1.3	A640S	Pathogenic	0.964
OPA1	O60313-1.3	A640T	Pathogenic	0.99
OPA1	O60313-1.3	A640V	Pathogenic	0.976
OPA1	O60313-1.3	A640W	Pathogenic	0.997
OPA1	O60313-1.3	A640Y	Pathogenic	0.997
OPA1	O60313-1.3	A641C	Pathogenic	0.982
OPA1	O60313-1.3	A641D	Pathogenic	0.997
OPA1	O60313-1.3	A641E	Pathogenic	0.991
OPA1	O60313-1.3	A641F	Pathogenic	0.995
OPA1	O60313-1.3	A641G	Pathogenic	0.987
OPA1	O60313-1.3	A641H	Pathogenic	0.998
OPA1	O60313-1.3	A641I	Pathogenic	0.985
OPA1	O60313-1.3	A641K	Pathogenic	0.987
OPA1	O60313-1.3	A641L	Pathogenic	0.986
OPA1	O60313-1.3	A641M	Pathogenic	0.991
OPA1	O60313-1.3	A641N	Pathogenic	0.997
OPA1	O60313-1.3	A641P	Pathogenic	0.995
OPA1	O60313-1.3	A641Q	Pathogenic	0.994
OPA1	O60313-1.3	A641R	Pathogenic	0.986
OPA1	O60313-1.3	A641S	Pathogenic	0.964
OPA1	O60313-1.3	A641T	Pathogenic	0.99
OPA1	O60313-1.3	A641V	Pathogenic	0.976
OPA1	O60313-1.3	A641W	Pathogenic	0.997
OPA1	O60313-1.3	A641Y	Pathogenic	0.997
OPA1	O60313-1.3	Q642A	Pathogenic	0.994
OPA1	O60313-1.3	Q642C	Pathogenic	0.999
OPA1	O60313-1.3	Q642D	Pathogenic	0.984
OPA1	O60313-1.3	Q642E	Pathogenic	0.9
OPA1	O60313-1.3	Q642F	Pathogenic	0.998
OPA1	O60313-1.3	Q642G	Pathogenic	0.998
OPA1	O60313-1.3	Q642H	Pathogenic	0.988
OPA1	O60313-1.3	Q642I	Pathogenic	0.998
OPA1	O60313-1.3	Q642K	Pathogenic	0.947
OPA1	O60313-1.3	Q642L	Pathogenic	0.994
OPA1	O60313-1.3	Q642M	Pathogenic	0.967
OPA1	O60313-1.3	Q642N	Pathogenic	0.987
OPA1	O60313-1.3	Q642P	Pathogenic	0.992
OPA1	O60313-1.3	Q642R	Pathogenic	0.944
OPA1	O60313-1.3	Q642S	Pathogenic	0.988
OPA1	O60313-1.3	Q642T	Pathogenic	0.995
OPA1	O60313-1.3	Q642V	Pathogenic	0.996
OPA1	O60313-1.3	Q642W	Pathogenic	0.988
OPA1	O60313-1.3	Q642Y	Pathogenic	0.99
OPA1	O60313-1.3	T643A	Pathogenic	0.865
OPA1	O60313-1.3	T643C	Pathogenic	0.915
OPA1	O60313-1.3	T643D	Pathogenic	0.893
OPA1	O60313-1.3	T643E	Pathogenic	0.899
OPA1	O60313-1.3	T643F	Pathogenic	0.929
OPA1	O60313-1.3	T643G	Pathogenic	0.977
OPA1	O60313-1.3	T643H	Pathogenic	0.981
OPA1	O60313-1.3	T643I	Pathogenic	0.823
OPA1	O60313-1.3	T643K	Pathogenic	0.854
OPA1	O60313-1.3	T643L	Pathogenic	0.836
OPA1	O60313-1.3	T643M	Pathogenic	0.887
OPA1	O60313-1.3	T643N	Pathogenic	0.769
OPA1	O60313-1.3	T643P	Pathogenic	0.933
OPA1	O60313-1.3	T643Q	Pathogenic	0.928
OPA1	O60313-1.3	T643R	Pathogenic	0.846
OPA1	O60313-1.3	T643S	Pathogenic	0.644
OPA1	O60313-1.3	T643V	Pathogenic	0.746
OPA1	O60313-1.3	T643W	Pathogenic	0.885
OPA1	O60313-1.3	T643Y	Pathogenic	0.965
OPA1	O60313-1.3	M644A	Neutral	0.496
OPA1	O60313-1.3	M644C	Pathogenic	0.662
OPA1	O60313-1.3	M644D	Pathogenic	0.771
OPA1	O60313-1.3	M644E	Pathogenic	0.584
OPA1	O60313-1.3	M644F	Neutral	0.361
OPA1	O60313-1.3	M644G	Pathogenic	0.853
OPA1	O60313-1.3	M644H	Pathogenic	0.746
OPA1	O60313-1.3	M644I	Neutral	0.167
OPA1	O60313-1.3	M644K	Neutral	0.263
OPA1	O60313-1.3	M644L	Neutral	0.07
OPA1	O60313-1.3	M644N	Pathogenic	0.58
OPA1	O60313-1.3	M644P	Pathogenic	0.819
OPA1	O60313-1.3	M644Q	Neutral	0.2
OPA1	O60313-1.3	M644R	Neutral	0.251
OPA1	O60313-1.3	M644S	Neutral	0.423
OPA1	O60313-1.3	M644T	Pathogenic	0.509
OPA1	O60313-1.3	M644V	Neutral	0.237
OPA1	O60313-1.3	M644W	Neutral	0.491
OPA1	O60313-1.3	M644Y	Pathogenic	0.675
OPA1	O60313-1.3	N645A	Pathogenic	0.902
OPA1	O60313-1.3	N645C	Pathogenic	0.939
OPA1	O60313-1.3	N645D	Neutral	0.447
OPA1	O60313-1.3	N645E	Pathogenic	0.72
OPA1	O60313-1.3	N645F	Pathogenic	0.868
OPA1	O60313-1.3	N645G	Pathogenic	0.574
OPA1	O60313-1.3	N645H	Neutral	0.312
OPA1	O60313-1.3	N645I	Pathogenic	0.871
OPA1	O60313-1.3	N645K	Pathogenic	0.628
OPA1	O60313-1.3	N645L	Pathogenic	0.882
OPA1	O60313-1.3	N645M	Pathogenic	0.798
OPA1	O60313-1.3	N645P	Pathogenic	0.873
OPA1	O60313-1.3	N645Q	Pathogenic	0.648
OPA1	O60313-1.3	N645R	Pathogenic	0.614
OPA1	O60313-1.3	N645S	Neutral	0.345
OPA1	O60313-1.3	N645T	Pathogenic	0.557
OPA1	O60313-1.3	N645V	Pathogenic	0.926
OPA1	O60313-1.3	N645W	Pathogenic	0.919
OPA1	O60313-1.3	N645Y	Pathogenic	0.826
OPA1	O60313-1.3	S646A	Neutral	0.295
OPA1	O60313-1.3	S646C	Pathogenic	0.649
OPA1	O60313-1.3	S646D	Neutral	0.448
OPA1	O60313-1.3	S646E	Neutral	0.462
OPA1	O60313-1.3	S646F	Pathogenic	0.681
OPA1	O60313-1.3	S646G	Pathogenic	0.6
OPA1	O60313-1.3	S646H	Pathogenic	0.781
OPA1	O60313-1.3	S646I	Pathogenic	0.687
OPA1	O60313-1.3	S646K	Neutral	0.36
OPA1	O60313-1.3	S646L	Pathogenic	0.707
OPA1	O60313-1.3	S646M	Pathogenic	0.561
OPA1	O60313-1.3	S646N	Neutral	0.243
OPA1	O60313-1.3	S646P	Pathogenic	0.699
OPA1	O60313-1.3	S646Q	Pathogenic	0.552
OPA1	O60313-1.3	S646R	Pathogenic	0.606
OPA1	O60313-1.3	S646T	Neutral	0.294
OPA1	O60313-1.3	S646V	Pathogenic	0.801
OPA1	O60313-1.3	S646W	Pathogenic	0.785
OPA1	O60313-1.3	S646Y	Pathogenic	0.816
OPA1	O60313-1.3	G647A	Pathogenic	0.843
OPA1	O60313-1.3	G647C	Pathogenic	0.985
OPA1	O60313-1.3	G647D	Pathogenic	0.903
OPA1	O60313-1.3	G647E	Pathogenic	0.966
OPA1	O60313-1.3	G647F	Pathogenic	0.963
OPA1	O60313-1.3	G647H	Pathogenic	0.978
OPA1	O60313-1.3	G647I	Pathogenic	0.987
OPA1	O60313-1.3	G647K	Pathogenic	0.949
OPA1	O60313-1.3	G647L	Pathogenic	0.988
OPA1	O60313-1.3	G647M	Pathogenic	0.978
OPA1	O60313-1.3	G647N	Pathogenic	0.786
OPA1	O60313-1.3	G647P	Pathogenic	0.966
OPA1	O60313-1.3	G647Q	Pathogenic	0.976
OPA1	O60313-1.3	G647R	Pathogenic	0.946
OPA1	O60313-1.3	G647S	Pathogenic	0.871
OPA1	O60313-1.3	G647T	Pathogenic	0.977
OPA1	O60313-1.3	G647V	Pathogenic	0.98
OPA1	O60313-1.3	G647W	Pathogenic	0.842
OPA1	O60313-1.3	G647Y	Pathogenic	0.982
OPA1	O60313-1.3	T648A	Pathogenic	0.941
OPA1	O60313-1.3	T648C	Pathogenic	0.964
OPA1	O60313-1.3	T648D	Pathogenic	0.954
OPA1	O60313-1.3	T648E	Pathogenic	0.957
OPA1	O60313-1.3	T648F	Pathogenic	0.97
OPA1	O60313-1.3	T648G	Pathogenic	0.99
OPA1	O60313-1.3	T648H	Pathogenic	0.992
OPA1	O60313-1.3	T648I	Pathogenic	0.92
OPA1	O60313-1.3	T648K	Pathogenic	0.936
OPA1	O60313-1.3	T648L	Pathogenic	0.927
OPA1	O60313-1.3	T648M	Pathogenic	0.951
OPA1	O60313-1.3	T648N	Pathogenic	0.892
OPA1	O60313-1.3	T648P	Pathogenic	0.972
OPA1	O60313-1.3	T648Q	Pathogenic	0.969
OPA1	O60313-1.3	T648R	Pathogenic	0.932
OPA1	O60313-1.3	T648S	Pathogenic	0.818
OPA1	O60313-1.3	T648V	Pathogenic	0.879
OPA1	O60313-1.3	T648W	Pathogenic	0.95
OPA1	O60313-1.3	T648Y	Pathogenic	0.985
OPA1	O60313-1.3	F649A	Pathogenic	0.996
OPA1	O60313-1.3	F649C	Pathogenic	0.998
OPA1	O60313-1.3	F649D	Pathogenic	0.996
OPA1	O60313-1.3	F649E	Pathogenic	0.997
OPA1	O60313-1.3	F649G	Pathogenic	0.998
OPA1	O60313-1.3	F649H	Pathogenic	0.988
OPA1	O60313-1.3	F649I	Pathogenic	0.992
OPA1	O60313-1.3	F649K	Pathogenic	0.996
OPA1	O60313-1.3	F649L	Pathogenic	0.992
OPA1	O60313-1.3	F649M	Pathogenic	0.987
OPA1	O60313-1.3	F649N	Pathogenic	0.997
OPA1	O60313-1.3	F649P	Pathogenic	1.0
OPA1	O60313-1.3	F649Q	Pathogenic	0.998
OPA1	O60313-1.3	F649R	Pathogenic	0.996
OPA1	O60313-1.3	F649S	Pathogenic	0.994
OPA1	O60313-1.3	F649T	Pathogenic	0.996
OPA1	O60313-1.3	F649V	Pathogenic	0.995
OPA1	O60313-1.3	F649W	Pathogenic	0.965
OPA1	O60313-1.3	F649Y	Pathogenic	0.718
OPA1	O60313-1.3	N650A	Pathogenic	0.998
OPA1	O60313-1.3	N650C	Pathogenic	0.999
OPA1	O60313-1.3	N650D	Pathogenic	0.974
OPA1	O60313-1.3	N650E	Pathogenic	0.992
OPA1	O60313-1.3	N650F	Pathogenic	0.997
OPA1	O60313-1.3	N650G	Pathogenic	0.984
OPA1	O60313-1.3	N650H	Pathogenic	0.954
OPA1	O60313-1.3	N650I	Pathogenic	0.997
OPA1	O60313-1.3	N650K	Pathogenic	0.987
OPA1	O60313-1.3	N650L	Pathogenic	0.997
OPA1	O60313-1.3	N650M	Pathogenic	0.994
OPA1	O60313-1.3	N650P	Pathogenic	0.997
OPA1	O60313-1.3	N650Q	Pathogenic	0.988
OPA1	O60313-1.3	N650R	Pathogenic	0.986
OPA1	O60313-1.3	N650S	Pathogenic	0.96
OPA1	O60313-1.3	N650T	Pathogenic	0.983
OPA1	O60313-1.3	N650V	Pathogenic	0.998
OPA1	O60313-1.3	N650W	Pathogenic	0.998
OPA1	O60313-1.3	N650Y	Pathogenic	0.995
OPA1	O60313-1.3	T651A	Pathogenic	0.99
OPA1	O60313-1.3	T651C	Pathogenic	0.994
OPA1	O60313-1.3	T651D	Pathogenic	0.992
OPA1	O60313-1.3	T651E	Pathogenic	0.993
OPA1	O60313-1.3	T651F	Pathogenic	0.995
OPA1	O60313-1.3	T651G	Pathogenic	0.998
OPA1	O60313-1.3	T651H	Pathogenic	0.999
OPA1	O60313-1.3	T651I	Pathogenic	0.986
OPA1	O60313-1.3	T651K	Pathogenic	0.989
OPA1	O60313-1.3	T651L	Pathogenic	0.987
OPA1	O60313-1.3	T651M	Pathogenic	0.992
OPA1	O60313-1.3	T651N	Pathogenic	0.981
OPA1	O60313-1.3	T651P	Pathogenic	0.995
OPA1	O60313-1.3	T651Q	Pathogenic	0.995
OPA1	O60313-1.3	T651R	Pathogenic	0.988
OPA1	O60313-1.3	T651S	Pathogenic	0.965
OPA1	O60313-1.3	T651V	Pathogenic	0.978
OPA1	O60313-1.3	T651W	Pathogenic	0.992
OPA1	O60313-1.3	T651Y	Pathogenic	0.998
OPA1	O60313-1.3	T652A	Pathogenic	0.951
OPA1	O60313-1.3	T652C	Pathogenic	0.97
OPA1	O60313-1.3	T652D	Pathogenic	0.962
OPA1	O60313-1.3	T652E	Pathogenic	0.964
OPA1	O60313-1.3	T652F	Pathogenic	0.975
OPA1	O60313-1.3	T652G	Pathogenic	0.992
OPA1	O60313-1.3	T652H	Pathogenic	0.994
OPA1	O60313-1.3	T652I	Pathogenic	0.934
OPA1	O60313-1.3	T652K	Pathogenic	0.947
OPA1	O60313-1.3	T652L	Pathogenic	0.939
OPA1	O60313-1.3	T652M	Pathogenic	0.96
OPA1	O60313-1.3	T652N	Pathogenic	0.91
OPA1	O60313-1.3	T652P	Pathogenic	0.977
OPA1	O60313-1.3	T652Q	Pathogenic	0.975
OPA1	O60313-1.3	T652R	Pathogenic	0.944
OPA1	O60313-1.3	T652S	Pathogenic	0.846
OPA1	O60313-1.3	T652V	Pathogenic	0.899
OPA1	O60313-1.3	T652W	Pathogenic	0.959
OPA1	O60313-1.3	T652Y	Pathogenic	0.988
OPA1	O60313-1.3	V653A	Pathogenic	0.975
OPA1	O60313-1.3	V653C	Pathogenic	0.996
OPA1	O60313-1.3	V653D	Pathogenic	0.997
OPA1	O60313-1.3	V653E	Pathogenic	0.994
OPA1	O60313-1.3	V653F	Pathogenic	0.994
OPA1	O60313-1.3	V653G	Pathogenic	0.999
OPA1	O60313-1.3	V653H	Pathogenic	0.999
OPA1	O60313-1.3	V653I	Pathogenic	0.7
OPA1	O60313-1.3	V653K	Pathogenic	0.99
OPA1	O60313-1.3	V653L	Pathogenic	0.956
OPA1	O60313-1.3	V653M	Pathogenic	0.971
OPA1	O60313-1.3	V653N	Pathogenic	0.998
OPA1	O60313-1.3	V653P	Pathogenic	0.998
OPA1	O60313-1.3	V653Q	Pathogenic	0.996
OPA1	O60313-1.3	V653R	Pathogenic	0.996
OPA1	O60313-1.3	V653S	Pathogenic	0.996
OPA1	O60313-1.3	V653T	Pathogenic	0.976
OPA1	O60313-1.3	V653W	Pathogenic	0.999
OPA1	O60313-1.3	V653Y	Pathogenic	0.995
OPA1	O60313-1.3	D654A	Pathogenic	0.997
OPA1	O60313-1.3	D654C	Pathogenic	0.998
OPA1	O60313-1.3	D654E	Pathogenic	0.914
OPA1	O60313-1.3	D654F	Pathogenic	0.995
OPA1	O60313-1.3	D654G	Pathogenic	0.992
OPA1	O60313-1.3	D654H	Pathogenic	0.992
OPA1	O60313-1.3	D654I	Pathogenic	0.995
OPA1	O60313-1.3	D654K	Pathogenic	0.995
OPA1	O60313-1.3	D654L	Pathogenic	0.999
OPA1	O60313-1.3	D654M	Pathogenic	0.997
OPA1	O60313-1.3	D654N	Pathogenic	0.969
OPA1	O60313-1.3	D654P	Pathogenic	0.988
OPA1	O60313-1.3	D654Q	Pathogenic	0.983
OPA1	O60313-1.3	D654R	Pathogenic	0.998
OPA1	O60313-1.3	D654S	Pathogenic	0.981
OPA1	O60313-1.3	D654T	Pathogenic	0.992
OPA1	O60313-1.3	D654V	Pathogenic	0.998
OPA1	O60313-1.3	D654W	Pathogenic	0.997
OPA1	O60313-1.3	D654Y	Pathogenic	0.998
OPA1	O60313-1.3	I655A	Pathogenic	0.985
OPA1	O60313-1.3	I655C	Pathogenic	0.993
OPA1	O60313-1.3	I655D	Pathogenic	0.996
OPA1	O60313-1.3	I655E	Pathogenic	0.996
OPA1	O60313-1.3	I655F	Pathogenic	0.991
OPA1	O60313-1.3	I655G	Pathogenic	0.999
OPA1	O60313-1.3	I655H	Pathogenic	0.998
OPA1	O60313-1.3	I655K	Pathogenic	0.995
OPA1	O60313-1.3	I655L	Pathogenic	0.925
OPA1	O60313-1.3	I655M	Pathogenic	0.959
OPA1	O60313-1.3	I655N	Pathogenic	0.996
OPA1	O60313-1.3	I655P	Pathogenic	0.999
OPA1	O60313-1.3	I655Q	Pathogenic	0.998
OPA1	O60313-1.3	I655R	Pathogenic	0.995
OPA1	O60313-1.3	I655S	Pathogenic	0.993
OPA1	O60313-1.3	I655T	Pathogenic	0.986
OPA1	O60313-1.3	I655V	Pathogenic	0.717
OPA1	O60313-1.3	I655W	Pathogenic	0.999
OPA1	O60313-1.3	I655Y	Pathogenic	0.993
OPA1	O60313-1.3	K656A	Pathogenic	0.954
OPA1	O60313-1.3	K656C	Pathogenic	0.99
OPA1	O60313-1.3	K656D	Pathogenic	0.984
OPA1	O60313-1.3	K656E	Pathogenic	0.874
OPA1	O60313-1.3	K656F	Pathogenic	0.983
OPA1	O60313-1.3	K656G	Pathogenic	0.987
OPA1	O60313-1.3	K656H	Pathogenic	0.967
OPA1	O60313-1.3	K656I	Pathogenic	0.982
OPA1	O60313-1.3	K656L	Pathogenic	0.954
OPA1	O60313-1.3	K656M	Pathogenic	0.917
OPA1	O60313-1.3	K656N	Pathogenic	0.949
OPA1	O60313-1.3	K656P	Pathogenic	0.94
OPA1	O60313-1.3	K656Q	Pathogenic	0.828
OPA1	O60313-1.3	K656R	Pathogenic	0.773
OPA1	O60313-1.3	K656S	Pathogenic	0.91
OPA1	O60313-1.3	K656T	Pathogenic	0.96
OPA1	O60313-1.3	K656V	Pathogenic	0.968
OPA1	O60313-1.3	K656W	Pathogenic	0.972
OPA1	O60313-1.3	K656Y	Pathogenic	0.977
OPA1	O60313-1.3	L657A	Pathogenic	0.982
OPA1	O60313-1.3	L657C	Pathogenic	0.991
OPA1	O60313-1.3	L657D	Pathogenic	0.998
OPA1	O60313-1.3	L657E	Pathogenic	0.996
OPA1	O60313-1.3	L657F	Pathogenic	0.987
OPA1	O60313-1.3	L657G	Pathogenic	0.999
OPA1	O60313-1.3	L657H	Pathogenic	0.998
OPA1	O60313-1.3	L657I	Pathogenic	0.902
OPA1	O60313-1.3	L657K	Pathogenic	0.983
OPA1	O60313-1.3	L657M	Pathogenic	0.868
OPA1	O60313-1.3	L657N	Pathogenic	0.996
OPA1	O60313-1.3	L657P	Pathogenic	0.999
OPA1	O60313-1.3	L657Q	Pathogenic	0.992
OPA1	O60313-1.3	L657R	Pathogenic	0.982
OPA1	O60313-1.3	L657S	Pathogenic	0.992
OPA1	O60313-1.3	L657T	Pathogenic	0.983
OPA1	O60313-1.3	L657V	Pathogenic	0.946
OPA1	O60313-1.3	L657W	Pathogenic	0.997
OPA1	O60313-1.3	L657Y	Pathogenic	0.992
OPA1	O60313-1.3	K658A	Pathogenic	0.847
OPA1	O60313-1.3	K658C	Pathogenic	0.964
OPA1	O60313-1.3	K658D	Pathogenic	0.942
OPA1	O60313-1.3	K658E	Pathogenic	0.646
OPA1	O60313-1.3	K658F	Pathogenic	0.939
OPA1	O60313-1.3	K658G	Pathogenic	0.952
OPA1	O60313-1.3	K658H	Pathogenic	0.887
OPA1	O60313-1.3	K658I	Pathogenic	0.936
OPA1	O60313-1.3	K658L	Pathogenic	0.847
OPA1	O60313-1.3	K658M	Pathogenic	0.746
OPA1	O60313-1.3	K658N	Pathogenic	0.83
OPA1	O60313-1.3	K658P	Pathogenic	0.805
OPA1	O60313-1.3	K658Q	Pathogenic	0.559
OPA1	O60313-1.3	K658R	Neutral	0.474
OPA1	O60313-1.3	K658S	Pathogenic	0.727
OPA1	O60313-1.3	K658T	Pathogenic	0.864
OPA1	O60313-1.3	K658V	Pathogenic	0.889
OPA1	O60313-1.3	K658W	Pathogenic	0.901
OPA1	O60313-1.3	K658Y	Pathogenic	0.917
OPA1	O60313-1.3	Q659A	Pathogenic	0.951
OPA1	O60313-1.3	Q659C	Pathogenic	0.99
OPA1	O60313-1.3	Q659D	Pathogenic	0.878
OPA1	O60313-1.3	Q659E	Pathogenic	0.507
OPA1	O60313-1.3	Q659F	Pathogenic	0.979
OPA1	O60313-1.3	Q659G	Pathogenic	0.986
OPA1	O60313-1.3	Q659H	Pathogenic	0.902
OPA1	O60313-1.3	Q659I	Pathogenic	0.979
OPA1	O60313-1.3	Q659K	Pathogenic	0.671
OPA1	O60313-1.3	Q659L	Pathogenic	0.947
OPA1	O60313-1.3	Q659M	Pathogenic	0.767
OPA1	O60313-1.3	Q659N	Pathogenic	0.895
OPA1	O60313-1.3	Q659P	Pathogenic	0.936
OPA1	O60313-1.3	Q659R	Pathogenic	0.657
OPA1	O60313-1.3	Q659S	Pathogenic	0.904
OPA1	O60313-1.3	Q659T	Pathogenic	0.957
OPA1	O60313-1.3	Q659V	Pathogenic	0.966
OPA1	O60313-1.3	Q659W	Pathogenic	0.904
OPA1	O60313-1.3	Q659Y	Pathogenic	0.92
OPA1	O60313-1.3	W660A	Pathogenic	0.998
OPA1	O60313-1.3	W660C	Pathogenic	0.997
OPA1	O60313-1.3	W660D	Pathogenic	0.998
OPA1	O60313-1.3	W660E	Pathogenic	0.996
OPA1	O60313-1.3	W660F	Pathogenic	0.973
OPA1	O60313-1.3	W660G	Pathogenic	0.992
OPA1	O60313-1.3	W660H	Pathogenic	0.994
OPA1	O60313-1.3	W660I	Pathogenic	1.0
OPA1	O60313-1.3	W660K	Pathogenic	0.995
OPA1	O60313-1.3	W660L	Pathogenic	0.999
OPA1	O60313-1.3	W660M	Pathogenic	0.994
OPA1	O60313-1.3	W660N	Pathogenic	0.999
OPA1	O60313-1.3	W660P	Pathogenic	1.0
OPA1	O60313-1.3	W660Q	Pathogenic	0.992
OPA1	O60313-1.3	W660R	Pathogenic	0.995
OPA1	O60313-1.3	W660S	Pathogenic	0.997
OPA1	O60313-1.3	W660T	Pathogenic	0.995
OPA1	O60313-1.3	W660V	Pathogenic	0.999
OPA1	O60313-1.3	W660Y	Pathogenic	0.855
OPA1	O60313-1.3	T661A	Pathogenic	0.894
OPA1	O60313-1.3	T661C	Pathogenic	0.934
OPA1	O60313-1.3	T661D	Pathogenic	0.917
OPA1	O60313-1.3	T661E	Pathogenic	0.922
OPA1	O60313-1.3	T661F	Pathogenic	0.945
OPA1	O60313-1.3	T661G	Pathogenic	0.982
OPA1	O60313-1.3	T661H	Pathogenic	0.985
OPA1	O60313-1.3	T661I	Pathogenic	0.86
OPA1	O60313-1.3	T661K	Pathogenic	0.886
OPA1	O60313-1.3	T661L	Pathogenic	0.871
OPA1	O60313-1.3	T661M	Pathogenic	0.912
OPA1	O60313-1.3	T661N	Pathogenic	0.815
OPA1	O60313-1.3	T661P	Pathogenic	0.948
OPA1	O60313-1.3	T661Q	Pathogenic	0.944
OPA1	O60313-1.3	T661R	Pathogenic	0.879
OPA1	O60313-1.3	T661S	Pathogenic	0.705
OPA1	O60313-1.3	T661V	Pathogenic	0.795
OPA1	O60313-1.3	T661W	Pathogenic	0.911
OPA1	O60313-1.3	T661Y	Pathogenic	0.973
OPA1	O60313-1.3	D662A	Pathogenic	0.947
OPA1	O60313-1.3	D662C	Pathogenic	0.968
OPA1	O60313-1.3	D662E	Neutral	0.379
OPA1	O60313-1.3	D662F	Pathogenic	0.925
OPA1	O60313-1.3	D662G	Pathogenic	0.883
OPA1	O60313-1.3	D662H	Pathogenic	0.877
OPA1	O60313-1.3	D662I	Pathogenic	0.927
OPA1	O60313-1.3	D662K	Pathogenic	0.926
OPA1	O60313-1.3	D662L	Pathogenic	0.976
OPA1	O60313-1.3	D662M	Pathogenic	0.955
OPA1	O60313-1.3	D662N	Pathogenic	0.642
OPA1	O60313-1.3	D662P	Pathogenic	0.821
OPA1	O60313-1.3	D662Q	Pathogenic	0.774
OPA1	O60313-1.3	D662R	Pathogenic	0.971
OPA1	O60313-1.3	D662S	Pathogenic	0.747
OPA1	O60313-1.3	D662T	Pathogenic	0.874
OPA1	O60313-1.3	D662V	Pathogenic	0.959
OPA1	O60313-1.3	D662W	Pathogenic	0.955
OPA1	O60313-1.3	D662Y	Pathogenic	0.963
OPA1	O60313-1.3	K663A	Pathogenic	0.809
OPA1	O60313-1.3	K663C	Pathogenic	0.954
OPA1	O60313-1.3	K663D	Pathogenic	0.925
OPA1	O60313-1.3	K663E	Pathogenic	0.583
OPA1	O60313-1.3	K663F	Pathogenic	0.922
OPA1	O60313-1.3	K663G	Pathogenic	0.938
OPA1	O60313-1.3	K663H	Pathogenic	0.857
OPA1	O60313-1.3	K663I	Pathogenic	0.918
OPA1	O60313-1.3	K663L	Pathogenic	0.809
OPA1	O60313-1.3	K663M	Pathogenic	0.692
OPA1	O60313-1.3	K663N	Pathogenic	0.789
OPA1	O60313-1.3	K663P	Pathogenic	0.76
OPA1	O60313-1.3	K663Q	Neutral	0.493
OPA1	O60313-1.3	K663R	Neutral	0.408
OPA1	O60313-1.3	K663S	Pathogenic	0.672
OPA1	O60313-1.3	K663T	Pathogenic	0.83
OPA1	O60313-1.3	K663V	Pathogenic	0.86
OPA1	O60313-1.3	K663W	Pathogenic	0.875
OPA1	O60313-1.3	K663Y	Pathogenic	0.895
OPA1	O60313-1.3	Q664A	Pathogenic	0.971
OPA1	O60313-1.3	Q664C	Pathogenic	0.994
OPA1	O60313-1.3	Q664D	Pathogenic	0.926
OPA1	O60313-1.3	Q664E	Pathogenic	0.643
OPA1	O60313-1.3	Q664F	Pathogenic	0.988
OPA1	O60313-1.3	Q664G	Pathogenic	0.992
OPA1	O60313-1.3	Q664H	Pathogenic	0.942
OPA1	O60313-1.3	Q664I	Pathogenic	0.988
OPA1	O60313-1.3	Q664K	Pathogenic	0.781
OPA1	O60313-1.3	Q664L	Pathogenic	0.969
OPA1	O60313-1.3	Q664M	Pathogenic	0.852
OPA1	O60313-1.3	Q664N	Pathogenic	0.937
OPA1	O60313-1.3	Q664P	Pathogenic	0.962
OPA1	O60313-1.3	Q664R	Pathogenic	0.77
OPA1	O60313-1.3	Q664S	Pathogenic	0.943
OPA1	O60313-1.3	Q664T	Pathogenic	0.975
OPA1	O60313-1.3	Q664V	Pathogenic	0.98
OPA1	O60313-1.3	Q664W	Pathogenic	0.943
OPA1	O60313-1.3	Q664Y	Pathogenic	0.953
OPA1	O60313-1.3	L665A	Pathogenic	0.982
OPA1	O60313-1.3	L665C	Pathogenic	0.991
OPA1	O60313-1.3	L665D	Pathogenic	0.998
OPA1	O60313-1.3	L665E	Pathogenic	0.996
OPA1	O60313-1.3	L665F	Pathogenic	0.987
OPA1	O60313-1.3	L665G	Pathogenic	0.999
OPA1	O60313-1.3	L665H	Pathogenic	0.998
OPA1	O60313-1.3	L665I	Pathogenic	0.902
OPA1	O60313-1.3	L665K	Pathogenic	0.983
OPA1	O60313-1.3	L665M	Pathogenic	0.868
OPA1	O60313-1.3	L665N	Pathogenic	0.996
OPA1	O60313-1.3	L665P	Pathogenic	0.999
OPA1	O60313-1.3	L665Q	Pathogenic	0.992
OPA1	O60313-1.3	L665R	Pathogenic	0.982
OPA1	O60313-1.3	L665S	Pathogenic	0.992
OPA1	O60313-1.3	L665T	Pathogenic	0.983
OPA1	O60313-1.3	L665V	Pathogenic	0.946
OPA1	O60313-1.3	L665W	Pathogenic	0.997
OPA1	O60313-1.3	L665Y	Pathogenic	0.992
OPA1	O60313-1.3	P666A	Pathogenic	0.996
OPA1	O60313-1.3	P666C	Pathogenic	1.0
OPA1	O60313-1.3	P666D	Pathogenic	0.99
OPA1	O60313-1.3	P666E	Pathogenic	0.991
OPA1	O60313-1.3	P666F	Pathogenic	1.0
OPA1	O60313-1.3	P666G	Pathogenic	0.998
OPA1	O60313-1.3	P666H	Pathogenic	0.998
OPA1	O60313-1.3	P666I	Pathogenic	0.999
OPA1	O60313-1.3	P666K	Pathogenic	0.986
OPA1	O60313-1.3	P666L	Pathogenic	0.999
OPA1	O60313-1.3	P666M	Pathogenic	0.998
OPA1	O60313-1.3	P666N	Pathogenic	0.997
OPA1	O60313-1.3	P666Q	Pathogenic	0.994
OPA1	O60313-1.3	P666R	Pathogenic	0.995
OPA1	O60313-1.3	P666S	Pathogenic	0.995
OPA1	O60313-1.3	P666T	Pathogenic	0.996
OPA1	O60313-1.3	P666V	Pathogenic	0.999
OPA1	O60313-1.3	P666W	Pathogenic	0.999
OPA1	O60313-1.3	P666Y	Pathogenic	1.0
OPA1	O60313-1.3	N667A	Neutral	0.343
OPA1	O60313-1.3	N667C	Neutral	0.467
OPA1	O60313-1.3	N667D	Neutral	0.044
OPA1	O60313-1.3	N667E	Neutral	0.128
OPA1	O60313-1.3	N667F	Neutral	0.273
OPA1	O60313-1.3	N667G	Neutral	0.071
OPA1	O60313-1.3	N667H	Neutral	0.025
OPA1	O60313-1.3	N667I	Neutral	0.279
OPA1	O60313-1.3	N667K	Neutral	0.088
OPA1	O60313-1.3	N667L	Neutral	0.298
OPA1	O60313-1.3	N667M	Neutral	0.184
OPA1	O60313-1.3	N667P	Neutral	0.281
OPA1	O60313-1.3	N667Q	Neutral	0.095
OPA1	O60313-1.3	N667R	Neutral	0.083
OPA1	O60313-1.3	N667S	Neutral	0.029
OPA1	O60313-1.3	N667T	Neutral	0.067
OPA1	O60313-1.3	N667V	Neutral	0.415
OPA1	O60313-1.3	N667W	Neutral	0.392
OPA1	O60313-1.3	N667Y	Neutral	0.213
OPA1	O60313-1.3	K668A	Pathogenic	0.793
OPA1	O60313-1.3	K668C	Pathogenic	0.949
OPA1	O60313-1.3	K668D	Pathogenic	0.918
OPA1	O60313-1.3	K668E	Pathogenic	0.56
OPA1	O60313-1.3	K668F	Pathogenic	0.915
OPA1	O60313-1.3	K668G	Pathogenic	0.932
OPA1	O60313-1.3	K668H	Pathogenic	0.845
OPA1	O60313-1.3	K668I	Pathogenic	0.91
OPA1	O60313-1.3	K668L	Pathogenic	0.794
OPA1	O60313-1.3	K668M	Pathogenic	0.671
OPA1	O60313-1.3	K668N	Pathogenic	0.772
OPA1	O60313-1.3	K668P	Pathogenic	0.742
OPA1	O60313-1.3	K668Q	Neutral	0.469
OPA1	O60313-1.3	K668R	Neutral	0.385
OPA1	O60313-1.3	K668S	Pathogenic	0.65
OPA1	O60313-1.3	K668T	Pathogenic	0.816
OPA1	O60313-1.3	K668V	Pathogenic	0.848
OPA1	O60313-1.3	K668W	Pathogenic	0.864
OPA1	O60313-1.3	K668Y	Pathogenic	0.885
OPA1	O60313-1.3	A669C	Pathogenic	0.784
OPA1	O60313-1.3	A669D	Pathogenic	0.954
OPA1	O60313-1.3	A669E	Pathogenic	0.883
OPA1	O60313-1.3	A669F	Pathogenic	0.924
OPA1	O60313-1.3	A669G	Pathogenic	0.835
OPA1	O60313-1.3	A669H	Pathogenic	0.977
OPA1	O60313-1.3	A669I	Pathogenic	0.811
OPA1	O60313-1.3	A669K	Pathogenic	0.832
OPA1	O60313-1.3	A669L	Pathogenic	0.825
OPA1	O60313-1.3	A669M	Pathogenic	0.879
OPA1	O60313-1.3	A669N	Pathogenic	0.96
OPA1	O60313-1.3	A669P	Pathogenic	0.93
OPA1	O60313-1.3	A669Q	Pathogenic	0.916
OPA1	O60313-1.3	A669R	Pathogenic	0.823
OPA1	O60313-1.3	A669S	Pathogenic	0.64
OPA1	O60313-1.3	A669T	Pathogenic	0.862
OPA1	O60313-1.3	A669V	Pathogenic	0.732
OPA1	O60313-1.3	A669W	Pathogenic	0.954
OPA1	O60313-1.3	A669Y	Pathogenic	0.962
OPA1	O60313-1.3	V670A	Pathogenic	0.655
OPA1	O60313-1.3	V670C	Pathogenic	0.916
OPA1	O60313-1.3	V670D	Pathogenic	0.95
OPA1	O60313-1.3	V670E	Pathogenic	0.884
OPA1	O60313-1.3	V670F	Pathogenic	0.885
OPA1	O60313-1.3	V670G	Pathogenic	0.97
OPA1	O60313-1.3	V670H	Pathogenic	0.977
OPA1	O60313-1.3	V670I	Neutral	0.101
OPA1	O60313-1.3	V670K	Pathogenic	0.834
OPA1	O60313-1.3	V670L	Pathogenic	0.509
OPA1	O60313-1.3	V670M	Pathogenic	0.615
OPA1	O60313-1.3	V670N	Pathogenic	0.957
OPA1	O60313-1.3	V670P	Pathogenic	0.962
OPA1	O60313-1.3	V670Q	Pathogenic	0.916
OPA1	O60313-1.3	V670R	Pathogenic	0.932
OPA1	O60313-1.3	V670S	Pathogenic	0.923
OPA1	O60313-1.3	V670T	Pathogenic	0.666
OPA1	O60313-1.3	V670W	Pathogenic	0.975
OPA1	O60313-1.3	V670Y	Pathogenic	0.91
OPA1	O60313-1.3	E671A	Pathogenic	0.99
OPA1	O60313-1.3	E671C	Pathogenic	0.999
OPA1	O60313-1.3	E671D	Pathogenic	0.9
OPA1	O60313-1.3	E671F	Pathogenic	0.995
OPA1	O60313-1.3	E671G	Pathogenic	0.997
OPA1	O60313-1.3	E671H	Pathogenic	0.978
OPA1	O60313-1.3	E671I	Pathogenic	0.996
OPA1	O60313-1.3	E671K	Pathogenic	0.954
OPA1	O60313-1.3	E671L	Pathogenic	0.996
OPA1	O60313-1.3	E671M	Pathogenic	0.992
OPA1	O60313-1.3	E671N	Pathogenic	0.988
OPA1	O60313-1.3	E671P	Pathogenic	0.986
OPA1	O60313-1.3	E671Q	Pathogenic	0.88
OPA1	O60313-1.3	E671R	Pathogenic	0.983
OPA1	O60313-1.3	E671S	Pathogenic	0.979
OPA1	O60313-1.3	E671T	Pathogenic	0.991
OPA1	O60313-1.3	E671V	Pathogenic	0.993
OPA1	O60313-1.3	E671W	Pathogenic	0.992
OPA1	O60313-1.3	E671Y	Pathogenic	0.994
OPA1	O60313-1.3	V672A	Neutral	0.324
OPA1	O60313-1.3	V672C	Pathogenic	0.734
OPA1	O60313-1.3	V672D	Pathogenic	0.826
OPA1	O60313-1.3	V672E	Pathogenic	0.658
OPA1	O60313-1.3	V672F	Pathogenic	0.66
OPA1	O60313-1.3	V672G	Pathogenic	0.891
OPA1	O60313-1.3	V672H	Pathogenic	0.916
OPA1	O60313-1.3	V672I	Neutral	0.028
OPA1	O60313-1.3	V672K	Pathogenic	0.558
OPA1	O60313-1.3	V672L	Neutral	0.207
OPA1	O60313-1.3	V672M	Neutral	0.286
OPA1	O60313-1.3	V672N	Pathogenic	0.85
OPA1	O60313-1.3	V672P	Pathogenic	0.864
OPA1	O60313-1.3	V672Q	Pathogenic	0.734
OPA1	O60313-1.3	V672R	Pathogenic	0.775
OPA1	O60313-1.3	V672S	Pathogenic	0.75
OPA1	O60313-1.3	V672T	Neutral	0.335
OPA1	O60313-1.3	V672W	Pathogenic	0.906
OPA1	O60313-1.3	V672Y	Pathogenic	0.717
OPA1	O60313-1.3	A673C	Pathogenic	0.622
OPA1	O60313-1.3	A673D	Pathogenic	0.904
OPA1	O60313-1.3	A673E	Pathogenic	0.774
OPA1	O60313-1.3	A673F	Pathogenic	0.846
OPA1	O60313-1.3	A673G	Pathogenic	0.697
OPA1	O60313-1.3	A673H	Pathogenic	0.951
OPA1	O60313-1.3	A673I	Pathogenic	0.661
OPA1	O60313-1.3	A673K	Pathogenic	0.692
OPA1	O60313-1.3	A673L	Pathogenic	0.682
OPA1	O60313-1.3	A673M	Pathogenic	0.767
OPA1	O60313-1.3	A673N	Pathogenic	0.915
OPA1	O60313-1.3	A673P	Pathogenic	0.857
OPA1	O60313-1.3	A673Q	Pathogenic	0.831
OPA1	O60313-1.3	A673R	Pathogenic	0.679
OPA1	O60313-1.3	A673S	Neutral	0.446
OPA1	O60313-1.3	A673T	Pathogenic	0.739
OPA1	O60313-1.3	A673V	Pathogenic	0.553
OPA1	O60313-1.3	A673W	Pathogenic	0.904
OPA1	O60313-1.3	A673Y	Pathogenic	0.92
OPA1	O60313-1.3	W674A	Pathogenic	0.995
OPA1	O60313-1.3	W674C	Pathogenic	0.993
OPA1	O60313-1.3	W674D	Pathogenic	0.996
OPA1	O60313-1.3	W674E	Pathogenic	0.991
OPA1	O60313-1.3	W674F	Pathogenic	0.94
OPA1	O60313-1.3	W674G	Pathogenic	0.982
OPA1	O60313-1.3	W674H	Pathogenic	0.987
OPA1	O60313-1.3	W674I	Pathogenic	0.999
OPA1	O60313-1.3	W674K	Pathogenic	0.989
OPA1	O60313-1.3	W674L	Pathogenic	0.997
OPA1	O60313-1.3	W674M	Pathogenic	0.987
OPA1	O60313-1.3	W674N	Pathogenic	0.997
OPA1	O60313-1.3	W674P	Pathogenic	0.999
OPA1	O60313-1.3	W674Q	Pathogenic	0.982
OPA1	O60313-1.3	W674R	Pathogenic	0.989
OPA1	O60313-1.3	W674S	Pathogenic	0.994
OPA1	O60313-1.3	W674T	Pathogenic	0.988
OPA1	O60313-1.3	W674V	Pathogenic	0.998
OPA1	O60313-1.3	W674Y	Pathogenic	0.72
OPA1	O60313-1.3	E675A	Pathogenic	0.966
OPA1	O60313-1.3	E675C	Pathogenic	0.998
OPA1	O60313-1.3	E675D	Pathogenic	0.73
OPA1	O60313-1.3	E675F	Pathogenic	0.985
OPA1	O60313-1.3	E675G	Pathogenic	0.99
OPA1	O60313-1.3	E675H	Pathogenic	0.929
OPA1	O60313-1.3	E675I	Pathogenic	0.985
OPA1	O60313-1.3	E675K	Pathogenic	0.862
OPA1	O60313-1.3	E675L	Pathogenic	0.987
OPA1	O60313-1.3	E675M	Pathogenic	0.975
OPA1	O60313-1.3	E675N	Pathogenic	0.962
OPA1	O60313-1.3	E675P	Pathogenic	0.955
OPA1	O60313-1.3	E675Q	Pathogenic	0.687
OPA1	O60313-1.3	E675R	Pathogenic	0.944
OPA1	O60313-1.3	E675S	Pathogenic	0.933
OPA1	O60313-1.3	E675T	Pathogenic	0.971
OPA1	O60313-1.3	E675V	Pathogenic	0.977
OPA1	O60313-1.3	E675W	Pathogenic	0.975
OPA1	O60313-1.3	E675Y	Pathogenic	0.979
OPA1	O60313-1.3	T676A	Pathogenic	0.649
OPA1	O60313-1.3	T676C	Pathogenic	0.756
OPA1	O60313-1.3	T676D	Pathogenic	0.706
OPA1	O60313-1.3	T676E	Pathogenic	0.72
OPA1	O60313-1.3	T676F	Pathogenic	0.79
OPA1	O60313-1.3	T676G	Pathogenic	0.923
OPA1	O60313-1.3	T676H	Pathogenic	0.936
OPA1	O60313-1.3	T676I	Pathogenic	0.572
OPA1	O60313-1.3	T676K	Pathogenic	0.628
OPA1	O60313-1.3	T676L	Pathogenic	0.595
OPA1	O60313-1.3	T676M	Pathogenic	0.693
OPA1	O60313-1.3	T676N	Neutral	0.49
OPA1	O60313-1.3	T676P	Pathogenic	0.8
OPA1	O60313-1.3	T676Q	Pathogenic	0.787
OPA1	O60313-1.3	T676R	Pathogenic	0.614
OPA1	O60313-1.3	T676S	Neutral	0.343
OPA1	O60313-1.3	T676V	Neutral	0.459
OPA1	O60313-1.3	T676W	Pathogenic	0.69
OPA1	O60313-1.3	T676Y	Pathogenic	0.887
OPA1	O60313-1.3	L677A	Pathogenic	0.96
OPA1	O60313-1.3	L677C	Pathogenic	0.98
OPA1	O60313-1.3	L677D	Pathogenic	0.996
OPA1	O60313-1.3	L677E	Pathogenic	0.99
OPA1	O60313-1.3	L677F	Pathogenic	0.97
OPA1	O60313-1.3	L677G	Pathogenic	0.998
OPA1	O60313-1.3	L677H	Pathogenic	0.995
OPA1	O60313-1.3	L677I	Pathogenic	0.801
OPA1	O60313-1.3	L677K	Pathogenic	0.962
OPA1	O60313-1.3	L677M	Pathogenic	0.742
OPA1	O60313-1.3	L677N	Pathogenic	0.99
OPA1	O60313-1.3	L677P	Pathogenic	0.997
OPA1	O60313-1.3	L677Q	Pathogenic	0.981
OPA1	O60313-1.3	L677R	Pathogenic	0.96
OPA1	O60313-1.3	L677S	Pathogenic	0.981
OPA1	O60313-1.3	L677T	Pathogenic	0.962
OPA1	O60313-1.3	L677V	Pathogenic	0.884
OPA1	O60313-1.3	L677W	Pathogenic	0.994
OPA1	O60313-1.3	L677Y	Pathogenic	0.981
OPA1	O60313-1.3	Q678A	Pathogenic	0.958
OPA1	O60313-1.3	Q678C	Pathogenic	0.991
OPA1	O60313-1.3	Q678D	Pathogenic	0.894
OPA1	O60313-1.3	Q678E	Pathogenic	0.547
OPA1	O60313-1.3	Q678F	Pathogenic	0.982
OPA1	O60313-1.3	Q678G	Pathogenic	0.988
OPA1	O60313-1.3	Q678H	Pathogenic	0.915
OPA1	O60313-1.3	Q678I	Pathogenic	0.982
OPA1	O60313-1.3	Q678K	Pathogenic	0.705
OPA1	O60313-1.3	Q678L	Pathogenic	0.955
OPA1	O60313-1.3	Q678M	Pathogenic	0.794
OPA1	O60313-1.3	Q678N	Pathogenic	0.909
OPA1	O60313-1.3	Q678P	Pathogenic	0.944
OPA1	O60313-1.3	Q678R	Pathogenic	0.692
OPA1	O60313-1.3	Q678S	Pathogenic	0.917
OPA1	O60313-1.3	Q678T	Pathogenic	0.963
OPA1	O60313-1.3	Q678V	Pathogenic	0.971
OPA1	O60313-1.3	Q678W	Pathogenic	0.917
OPA1	O60313-1.3	Q678Y	Pathogenic	0.931
OPA1	O60313-1.3	E679A	Neutral	0.33
OPA1	O60313-1.3	E679C	Pathogenic	0.874
OPA1	O60313-1.3	E679D	Neutral	0.044
OPA1	O60313-1.3	E679F	Pathogenic	0.531
OPA1	O60313-1.3	E679G	Pathogenic	0.638
OPA1	O60313-1.3	E679H	Neutral	0.184
OPA1	O60313-1.3	E679I	Pathogenic	0.538
OPA1	O60313-1.3	E679K	Neutral	0.097
OPA1	O60313-1.3	E679L	Pathogenic	0.561
OPA1	O60313-1.3	E679M	Neutral	0.404
OPA1	O60313-1.3	E679N	Neutral	0.303
OPA1	O60313-1.3	E679P	Neutral	0.269
OPA1	O60313-1.3	E679Q	Neutral	0.036
OPA1	O60313-1.3	E679R	Neutral	0.226
OPA1	O60313-1.3	E679S	Neutral	0.192
OPA1	O60313-1.3	E679T	Neutral	0.362
OPA1	O60313-1.3	E679V	Neutral	0.417
OPA1	O60313-1.3	E679W	Neutral	0.401
OPA1	O60313-1.3	E679Y	Neutral	0.449
OPA1	O60313-1.3	E680A	Pathogenic	0.977
OPA1	O60313-1.3	E680C	Pathogenic	0.998
OPA1	O60313-1.3	E680D	Pathogenic	0.797
OPA1	O60313-1.3	E680F	Pathogenic	0.99
OPA1	O60313-1.3	E680G	Pathogenic	0.993
OPA1	O60313-1.3	E680H	Pathogenic	0.95
OPA1	O60313-1.3	E680I	Pathogenic	0.99
OPA1	O60313-1.3	E680K	Pathogenic	0.9
OPA1	O60313-1.3	E680L	Pathogenic	0.991
OPA1	O60313-1.3	E680M	Pathogenic	0.983
OPA1	O60313-1.3	E680N	Pathogenic	0.974
OPA1	O60313-1.3	E680P	Pathogenic	0.969
OPA1	O60313-1.3	E680Q	Pathogenic	0.761
OPA1	O60313-1.3	E680R	Pathogenic	0.961
OPA1	O60313-1.3	E680S	Pathogenic	0.953
OPA1	O60313-1.3	E680T	Pathogenic	0.98
OPA1	O60313-1.3	E680V	Pathogenic	0.984
OPA1	O60313-1.3	E680W	Pathogenic	0.983
OPA1	O60313-1.3	E680Y	Pathogenic	0.986
OPA1	O60313-1.3	F681A	Pathogenic	0.99
OPA1	O60313-1.3	F681C	Pathogenic	0.995
OPA1	O60313-1.3	F681D	Pathogenic	0.992
OPA1	O60313-1.3	F681E	Pathogenic	0.993
OPA1	O60313-1.3	F681G	Pathogenic	0.995
OPA1	O60313-1.3	F681H	Pathogenic	0.972
OPA1	O60313-1.3	F681I	Pathogenic	0.982
OPA1	O60313-1.3	F681K	Pathogenic	0.991
OPA1	O60313-1.3	F681L	Pathogenic	0.981
OPA1	O60313-1.3	F681M	Pathogenic	0.971
OPA1	O60313-1.3	F681N	Pathogenic	0.993
OPA1	O60313-1.3	F681P	Pathogenic	0.999
OPA1	O60313-1.3	F681Q	Pathogenic	0.995
OPA1	O60313-1.3	F681R	Pathogenic	0.991
OPA1	O60313-1.3	F681S	Pathogenic	0.987
OPA1	O60313-1.3	F681T	Pathogenic	0.99
OPA1	O60313-1.3	F681V	Pathogenic	0.989
OPA1	O60313-1.3	F681W	Pathogenic	0.923
OPA1	O60313-1.3	F681Y	Pathogenic	0.525
OPA1	O60313-1.3	S682A	Neutral	0.026
OPA1	O60313-1.3	S682C	Neutral	0.107
OPA1	O60313-1.3	S682D	Neutral	0.05
OPA1	O60313-1.3	S682E	Neutral	0.053
OPA1	O60313-1.3	S682F	Neutral	0.122
OPA1	O60313-1.3	S682G	Neutral	0.089
OPA1	O60313-1.3	S682H	Neutral	0.188
OPA1	O60313-1.3	S682I	Neutral	0.125
OPA1	O60313-1.3	S682K	Neutral	0.035
OPA1	O60313-1.3	S682L	Neutral	0.135
OPA1	O60313-1.3	S682M	Neutral	0.077
OPA1	O60313-1.3	S682N	Neutral	0.02
OPA1	O60313-1.3	S682P	Neutral	0.131
OPA1	O60313-1.3	S682Q	Neutral	0.074
OPA1	O60313-1.3	S682R	Neutral	0.091
OPA1	O60313-1.3	S682T	Neutral	0.026
OPA1	O60313-1.3	S682V	Neutral	0.207
OPA1	O60313-1.3	S682W	Neutral	0.192
OPA1	O60313-1.3	S682Y	Neutral	0.224
OPA1	O60313-1.3	R683A	Neutral	0.246
OPA1	O60313-1.3	R683C	Pathogenic	0.614
OPA1	O60313-1.3	R683D	Pathogenic	0.736
OPA1	O60313-1.3	R683E	Neutral	0.239
OPA1	O60313-1.3	R683F	Neutral	0.477
OPA1	O60313-1.3	R683G	Pathogenic	0.539
OPA1	O60313-1.3	R683H	Neutral	0.138
OPA1	O60313-1.3	R683I	Neutral	0.464
OPA1	O60313-1.3	R683K	Neutral	0.054
OPA1	O60313-1.3	R683L	Neutral	0.247
OPA1	O60313-1.3	R683M	Neutral	0.148
OPA1	O60313-1.3	R683N	Neutral	0.224
OPA1	O60313-1.3	R683P	Neutral	0.415
OPA1	O60313-1.3	R683Q	Neutral	0.07
OPA1	O60313-1.3	R683S	Neutral	0.314
OPA1	O60313-1.3	R683T	Neutral	0.274
OPA1	O60313-1.3	R683V	Pathogenic	0.58
OPA1	O60313-1.3	R683W	Neutral	0.373
OPA1	O60313-1.3	R683Y	Neutral	0.408
OPA1	O60313-1.3	F684A	Pathogenic	0.963
OPA1	O60313-1.3	F684C	Pathogenic	0.981
OPA1	O60313-1.3	F684D	Pathogenic	0.968
OPA1	O60313-1.3	F684E	Pathogenic	0.974
OPA1	O60313-1.3	F684G	Pathogenic	0.981
OPA1	O60313-1.3	F684H	Pathogenic	0.901
OPA1	O60313-1.3	F684I	Pathogenic	0.936
OPA1	O60313-1.3	F684K	Pathogenic	0.967
OPA1	O60313-1.3	F684L	Pathogenic	0.931
OPA1	O60313-1.3	F684M	Pathogenic	0.898
OPA1	O60313-1.3	F684N	Pathogenic	0.973
OPA1	O60313-1.3	F684P	Pathogenic	0.997
OPA1	O60313-1.3	F684Q	Pathogenic	0.982
OPA1	O60313-1.3	F684R	Pathogenic	0.965
OPA1	O60313-1.3	F684S	Pathogenic	0.951
OPA1	O60313-1.3	F684T	Pathogenic	0.964
OPA1	O60313-1.3	F684V	Pathogenic	0.959
OPA1	O60313-1.3	F684W	Pathogenic	0.757
OPA1	O60313-1.3	F684Y	Neutral	0.224
OPA1	O60313-1.3	M685A	Pathogenic	0.971
OPA1	O60313-1.3	M685C	Pathogenic	0.985
OPA1	O60313-1.3	M685D	Pathogenic	0.991
OPA1	O60313-1.3	M685E	Pathogenic	0.979
OPA1	O60313-1.3	M685F	Pathogenic	0.95
OPA1	O60313-1.3	M685G	Pathogenic	0.995
OPA1	O60313-1.3	M685H	Pathogenic	0.99
OPA1	O60313-1.3	M685I	Pathogenic	0.87
OPA1	O60313-1.3	M685K	Pathogenic	0.923
OPA1	O60313-1.3	M685L	Pathogenic	0.718
OPA1	O60313-1.3	M685N	Pathogenic	0.979
OPA1	O60313-1.3	M685P	Pathogenic	0.993
OPA1	O60313-1.3	M685Q	Pathogenic	0.894
OPA1	O60313-1.3	M685R	Pathogenic	0.918
OPA1	O60313-1.3	M685S	Pathogenic	0.961
OPA1	O60313-1.3	M685T	Pathogenic	0.972
OPA1	O60313-1.3	M685V	Pathogenic	0.912
OPA1	O60313-1.3	M685W	Pathogenic	0.97
OPA1	O60313-1.3	M685Y	Pathogenic	0.986
OPA1	O60313-1.3	T686A	Neutral	0.058
OPA1	O60313-1.3	T686C	Neutral	0.094
OPA1	O60313-1.3	T686D	Neutral	0.075
OPA1	O60313-1.3	T686E	Neutral	0.079
OPA1	O60313-1.3	T686F	Neutral	0.112
OPA1	O60313-1.3	T686G	Neutral	0.287
OPA1	O60313-1.3	T686H	Neutral	0.329
OPA1	O60313-1.3	T686I	Neutral	0.043
OPA1	O60313-1.3	T686K	Neutral	0.054
OPA1	O60313-1.3	T686L	Neutral	0.047
OPA1	O60313-1.3	T686M	Neutral	0.07
OPA1	O60313-1.3	T686N	Neutral	0.031
OPA1	O60313-1.3	T686P	Neutral	0.119
OPA1	O60313-1.3	T686Q	Neutral	0.11
OPA1	O60313-1.3	T686R	Neutral	0.051
OPA1	O60313-1.3	T686S	Neutral	0.017
OPA1	O60313-1.3	T686V	Neutral	0.028
OPA1	O60313-1.3	T686W	Neutral	0.07
OPA1	O60313-1.3	T686Y	Neutral	0.209
OPA1	O60313-1.3	E687A	Neutral	0.475
OPA1	O60313-1.3	E687C	Pathogenic	0.927
OPA1	O60313-1.3	E687D	Neutral	0.079
OPA1	O60313-1.3	E687F	Pathogenic	0.675
OPA1	O60313-1.3	E687G	Pathogenic	0.764
OPA1	O60313-1.3	E687H	Neutral	0.293
OPA1	O60313-1.3	E687I	Pathogenic	0.681
OPA1	O60313-1.3	E687K	Neutral	0.164
OPA1	O60313-1.3	E687L	Pathogenic	0.701
OPA1	O60313-1.3	E687M	Pathogenic	0.554
OPA1	O60313-1.3	E687N	Neutral	0.444
OPA1	O60313-1.3	E687P	Neutral	0.403
OPA1	O60313-1.3	E687Q	Neutral	0.065
OPA1	O60313-1.3	E687R	Neutral	0.349
OPA1	O60313-1.3	E687S	Neutral	0.304
OPA1	O60313-1.3	E687T	Pathogenic	0.511
OPA1	O60313-1.3	E687V	Pathogenic	0.568
OPA1	O60313-1.3	E687W	Pathogenic	0.551
OPA1	O60313-1.3	E687Y	Pathogenic	0.599
OPA1	O60313-1.3	P688A	Neutral	0.018
OPA1	O60313-1.3	P688C	Neutral	0.162
OPA1	O60313-1.3	P688D	Neutral	0.008
OPA1	O60313-1.3	P688E	Neutral	0.008
OPA1	O60313-1.3	P688F	Neutral	0.187
OPA1	O60313-1.3	P688G	Neutral	0.037
OPA1	O60313-1.3	P688H	Neutral	0.043
OPA1	O60313-1.3	P688I	Neutral	0.075
OPA1	O60313-1.3	P688K	Neutral	0.005
OPA1	O60313-1.3	P688L	Neutral	0.082
OPA1	O60313-1.3	P688M	Neutral	0.045
OPA1	O60313-1.3	P688N	Neutral	0.025
OPA1	O60313-1.3	P688Q	Neutral	0.011
OPA1	O60313-1.3	P688R	Neutral	0.014
OPA1	O60313-1.3	P688S	Neutral	0.014
OPA1	O60313-1.3	P688T	Neutral	0.019
OPA1	O60313-1.3	P688V	Neutral	0.049
OPA1	O60313-1.3	P688W	Neutral	0.12
OPA1	O60313-1.3	P688Y	Neutral	0.142
OPA1	O60313-1.3	K689A	Pathogenic	0.862
OPA1	O60313-1.3	K689C	Pathogenic	0.968
OPA1	O60313-1.3	K689D	Pathogenic	0.948
OPA1	O60313-1.3	K689E	Pathogenic	0.674
OPA1	O60313-1.3	K689F	Pathogenic	0.946
OPA1	O60313-1.3	K689G	Pathogenic	0.957
OPA1	O60313-1.3	K689H	Pathogenic	0.899
OPA1	O60313-1.3	K689I	Pathogenic	0.943
OPA1	O60313-1.3	K689L	Pathogenic	0.863
OPA1	O60313-1.3	K689M	Pathogenic	0.769
OPA1	O60313-1.3	K689N	Pathogenic	0.847
OPA1	O60313-1.3	K689P	Pathogenic	0.824
OPA1	O60313-1.3	K689Q	Pathogenic	0.59
OPA1	O60313-1.3	K689R	Pathogenic	0.505
OPA1	O60313-1.3	K689S	Pathogenic	0.752
OPA1	O60313-1.3	K689T	Pathogenic	0.879
OPA1	O60313-1.3	K689V	Pathogenic	0.901
OPA1	O60313-1.3	K689W	Pathogenic	0.912
OPA1	O60313-1.3	K689Y	Pathogenic	0.926
OPA1	O60313-1.3	G690A	Pathogenic	0.624
OPA1	O60313-1.3	G690C	Pathogenic	0.953
OPA1	O60313-1.3	G690D	Pathogenic	0.742
OPA1	O60313-1.3	G690E	Pathogenic	0.898
OPA1	O60313-1.3	G690F	Pathogenic	0.89
OPA1	O60313-1.3	G690H	Pathogenic	0.931
OPA1	O60313-1.3	G690I	Pathogenic	0.96
OPA1	O60313-1.3	G690K	Pathogenic	0.853
OPA1	O60313-1.3	G690L	Pathogenic	0.964
OPA1	O60313-1.3	G690M	Pathogenic	0.933
OPA1	O60313-1.3	G690N	Pathogenic	0.532
OPA1	O60313-1.3	G690P	Pathogenic	0.898
OPA1	O60313-1.3	G690Q	Pathogenic	0.927
OPA1	O60313-1.3	G690R	Pathogenic	0.845
OPA1	O60313-1.3	G690S	Pathogenic	0.675
OPA1	O60313-1.3	G690T	Pathogenic	0.93
OPA1	O60313-1.3	G690V	Pathogenic	0.938
OPA1	O60313-1.3	G690W	Pathogenic	0.622
OPA1	O60313-1.3	G690Y	Pathogenic	0.944
OPA1	O60313-1.3	K691A	Pathogenic	0.561
OPA1	O60313-1.3	K691C	Pathogenic	0.862
OPA1	O60313-1.3	K691D	Pathogenic	0.79
OPA1	O60313-1.3	K691E	Neutral	0.297
OPA1	O60313-1.3	K691F	Pathogenic	0.781
OPA1	O60313-1.3	K691G	Pathogenic	0.821
OPA1	O60313-1.3	K691H	Pathogenic	0.645
OPA1	O60313-1.3	K691I	Pathogenic	0.772
OPA1	O60313-1.3	K691L	Pathogenic	0.562
OPA1	O60313-1.3	K691M	Neutral	0.405
OPA1	O60313-1.3	K691N	Pathogenic	0.531
OPA1	O60313-1.3	K691P	Neutral	0.489
OPA1	O60313-1.3	K691Q	Neutral	0.227
OPA1	O60313-1.3	K691R	Neutral	0.173
OPA1	O60313-1.3	K691S	Neutral	0.382
OPA1	O60313-1.3	K691T	Pathogenic	0.596
OPA1	O60313-1.3	K691V	Pathogenic	0.65
OPA1	O60313-1.3	K691W	Pathogenic	0.678
OPA1	O60313-1.3	K691Y	Pathogenic	0.72
OPA1	O60313-1.3	E692A	Pathogenic	0.512
OPA1	O60313-1.3	E692C	Pathogenic	0.937
OPA1	O60313-1.3	E692D	Neutral	0.09
OPA1	O60313-1.3	E692F	Pathogenic	0.707
OPA1	O60313-1.3	E692G	Pathogenic	0.79
OPA1	O60313-1.3	E692H	Neutral	0.325
OPA1	O60313-1.3	E692I	Pathogenic	0.713
OPA1	O60313-1.3	E692K	Neutral	0.186
OPA1	O60313-1.3	E692L	Pathogenic	0.732
OPA1	O60313-1.3	E692M	Pathogenic	0.591
OPA1	O60313-1.3	E692N	Neutral	0.481
OPA1	O60313-1.3	E692P	Neutral	0.44
OPA1	O60313-1.3	E692Q	Neutral	0.074
OPA1	O60313-1.3	E692R	Neutral	0.383
OPA1	O60313-1.3	E692S	Neutral	0.337
OPA1	O60313-1.3	E692T	Pathogenic	0.548
OPA1	O60313-1.3	E692V	Pathogenic	0.604
OPA1	O60313-1.3	E692W	Pathogenic	0.588
OPA1	O60313-1.3	E692Y	Pathogenic	0.635
OPA1	O60313-1.3	H693A	Pathogenic	0.957
OPA1	O60313-1.3	H693C	Pathogenic	0.974
OPA1	O60313-1.3	H693D	Pathogenic	0.812
OPA1	O60313-1.3	H693E	Pathogenic	0.643
OPA1	O60313-1.3	H693F	Pathogenic	0.692
OPA1	O60313-1.3	H693G	Pathogenic	0.956
OPA1	O60313-1.3	H693I	Pathogenic	0.951
OPA1	O60313-1.3	H693K	Pathogenic	0.786
OPA1	O60313-1.3	H693L	Pathogenic	0.955
OPA1	O60313-1.3	H693M	Pathogenic	0.919
OPA1	O60313-1.3	H693N	Neutral	0.38
OPA1	O60313-1.3	H693P	Pathogenic	0.943
OPA1	O60313-1.3	H693Q	Pathogenic	0.729
OPA1	O60313-1.3	H693R	Pathogenic	0.544
OPA1	O60313-1.3	H693S	Pathogenic	0.888
OPA1	O60313-1.3	H693T	Pathogenic	0.963
OPA1	O60313-1.3	H693V	Pathogenic	0.97
OPA1	O60313-1.3	H693W	Pathogenic	0.794
OPA1	O60313-1.3	H693Y	Neutral	0.162
OPA1	O60313-1.3	D694A	Pathogenic	0.993
OPA1	O60313-1.3	D694C	Pathogenic	0.996
OPA1	O60313-1.3	D694E	Pathogenic	0.821
OPA1	O60313-1.3	D694F	Pathogenic	0.989
OPA1	O60313-1.3	D694G	Pathogenic	0.983
OPA1	O60313-1.3	D694H	Pathogenic	0.982
OPA1	O60313-1.3	D694I	Pathogenic	0.99
OPA1	O60313-1.3	D694K	Pathogenic	0.989
OPA1	O60313-1.3	D694L	Pathogenic	0.997
OPA1	O60313-1.3	D694M	Pathogenic	0.994
OPA1	O60313-1.3	D694N	Pathogenic	0.931
OPA1	O60313-1.3	D694P	Pathogenic	0.972
OPA1	O60313-1.3	D694Q	Pathogenic	0.963
OPA1	O60313-1.3	D694R	Pathogenic	0.996
OPA1	O60313-1.3	D694S	Pathogenic	0.957
OPA1	O60313-1.3	D694T	Pathogenic	0.981
OPA1	O60313-1.3	D694V	Pathogenic	0.994
OPA1	O60313-1.3	D694W	Pathogenic	0.994
OPA1	O60313-1.3	D694Y	Pathogenic	0.995
OPA1	O60313-1.3	D695A	Pathogenic	0.979
OPA1	O60313-1.3	D695C	Pathogenic	0.987
OPA1	O60313-1.3	D695E	Pathogenic	0.611
OPA1	O60313-1.3	D695F	Pathogenic	0.969
OPA1	O60313-1.3	D695G	Pathogenic	0.951
OPA1	O60313-1.3	D695H	Pathogenic	0.948
OPA1	O60313-1.3	D695I	Pathogenic	0.97
OPA1	O60313-1.3	D695K	Pathogenic	0.97
OPA1	O60313-1.3	D695L	Pathogenic	0.99
OPA1	O60313-1.3	D695M	Pathogenic	0.982
OPA1	O60313-1.3	D695N	Pathogenic	0.822
OPA1	O60313-1.3	D695P	Pathogenic	0.922
OPA1	O60313-1.3	D695Q	Pathogenic	0.898
OPA1	O60313-1.3	D695R	Pathogenic	0.989
OPA1	O60313-1.3	D695S	Pathogenic	0.884
OPA1	O60313-1.3	D695T	Pathogenic	0.947
OPA1	O60313-1.3	D695V	Pathogenic	0.984
OPA1	O60313-1.3	D695W	Pathogenic	0.982
OPA1	O60313-1.3	D695Y	Pathogenic	0.985
OPA1	O60313-1.3	I696A	Pathogenic	0.933
OPA1	O60313-1.3	I696C	Pathogenic	0.965
OPA1	O60313-1.3	I696D	Pathogenic	0.98
OPA1	O60313-1.3	I696E	Pathogenic	0.983
OPA1	O60313-1.3	I696F	Pathogenic	0.957
OPA1	O60313-1.3	I696G	Pathogenic	0.996
OPA1	O60313-1.3	I696H	Pathogenic	0.992
OPA1	O60313-1.3	I696K	Pathogenic	0.977
OPA1	O60313-1.3	I696L	Pathogenic	0.717
OPA1	O60313-1.3	I696M	Pathogenic	0.827
OPA1	O60313-1.3	I696N	Pathogenic	0.983
OPA1	O60313-1.3	I696P	Pathogenic	0.995
OPA1	O60313-1.3	I696Q	Pathogenic	0.989
OPA1	O60313-1.3	I696R	Pathogenic	0.976
OPA1	O60313-1.3	I696S	Pathogenic	0.968
OPA1	O60313-1.3	I696T	Pathogenic	0.936
OPA1	O60313-1.3	I696V	Neutral	0.344
OPA1	O60313-1.3	I696W	Pathogenic	0.997
OPA1	O60313-1.3	I696Y	Pathogenic	0.967
OPA1	O60313-1.3	F697A	Pathogenic	0.99
OPA1	O60313-1.3	F697C	Pathogenic	0.995
OPA1	O60313-1.3	F697D	Pathogenic	0.992
OPA1	O60313-1.3	F697E	Pathogenic	0.993
OPA1	O60313-1.3	F697G	Pathogenic	0.995
OPA1	O60313-1.3	F697H	Pathogenic	0.972
OPA1	O60313-1.3	F697I	Pathogenic	0.982
OPA1	O60313-1.3	F697K	Pathogenic	0.991
OPA1	O60313-1.3	F697L	Pathogenic	0.981
OPA1	O60313-1.3	F697M	Pathogenic	0.971
OPA1	O60313-1.3	F697N	Pathogenic	0.993
OPA1	O60313-1.3	F697P	Pathogenic	0.999
OPA1	O60313-1.3	F697Q	Pathogenic	0.995
OPA1	O60313-1.3	F697R	Pathogenic	0.991
OPA1	O60313-1.3	F697S	Pathogenic	0.987
OPA1	O60313-1.3	F697T	Pathogenic	0.99
OPA1	O60313-1.3	F697V	Pathogenic	0.989
OPA1	O60313-1.3	F697W	Pathogenic	0.923
OPA1	O60313-1.3	F697Y	Pathogenic	0.525
OPA1	O60313-1.3	D698A	Pathogenic	0.993
OPA1	O60313-1.3	D698C	Pathogenic	0.996
OPA1	O60313-1.3	D698E	Pathogenic	0.821
OPA1	O60313-1.3	D698F	Pathogenic	0.989
OPA1	O60313-1.3	D698G	Pathogenic	0.983
OPA1	O60313-1.3	D698H	Pathogenic	0.982
OPA1	O60313-1.3	D698I	Pathogenic	0.99
OPA1	O60313-1.3	D698K	Pathogenic	0.989
OPA1	O60313-1.3	D698L	Pathogenic	0.997
OPA1	O60313-1.3	D698M	Pathogenic	0.994
OPA1	O60313-1.3	D698N	Pathogenic	0.931
OPA1	O60313-1.3	D698P	Pathogenic	0.972
OPA1	O60313-1.3	D698Q	Pathogenic	0.963
OPA1	O60313-1.3	D698R	Pathogenic	0.996
OPA1	O60313-1.3	D698S	Pathogenic	0.957
OPA1	O60313-1.3	D698T	Pathogenic	0.981
OPA1	O60313-1.3	D698V	Pathogenic	0.994
OPA1	O60313-1.3	D698W	Pathogenic	0.994
OPA1	O60313-1.3	D698Y	Pathogenic	0.995
OPA1	O60313-1.3	K699A	Pathogenic	0.549
OPA1	O60313-1.3	K699C	Pathogenic	0.856
OPA1	O60313-1.3	K699D	Pathogenic	0.781
OPA1	O60313-1.3	K699E	Neutral	0.287
OPA1	O60313-1.3	K699F	Pathogenic	0.773
OPA1	O60313-1.3	K699G	Pathogenic	0.813
OPA1	O60313-1.3	K699H	Pathogenic	0.634
OPA1	O60313-1.3	K699I	Pathogenic	0.763
OPA1	O60313-1.3	K699L	Pathogenic	0.55
OPA1	O60313-1.3	K699M	Neutral	0.393
OPA1	O60313-1.3	K699N	Pathogenic	0.518
OPA1	O60313-1.3	K699P	Neutral	0.477
OPA1	O60313-1.3	K699Q	Neutral	0.219
OPA1	O60313-1.3	K699R	Neutral	0.166
OPA1	O60313-1.3	K699S	Neutral	0.371
OPA1	O60313-1.3	K699T	Pathogenic	0.584
OPA1	O60313-1.3	K699V	Pathogenic	0.639
OPA1	O60313-1.3	K699W	Pathogenic	0.667
OPA1	O60313-1.3	K699Y	Pathogenic	0.71
OPA1	O60313-1.3	L700A	Pathogenic	0.96
OPA1	O60313-1.3	L700C	Pathogenic	0.98
OPA1	O60313-1.3	L700D	Pathogenic	0.996
OPA1	O60313-1.3	L700E	Pathogenic	0.99
OPA1	O60313-1.3	L700F	Pathogenic	0.97
OPA1	O60313-1.3	L700G	Pathogenic	0.998
OPA1	O60313-1.3	L700H	Pathogenic	0.995
OPA1	O60313-1.3	L700I	Pathogenic	0.801
OPA1	O60313-1.3	L700K	Pathogenic	0.962
OPA1	O60313-1.3	L700M	Pathogenic	0.742
OPA1	O60313-1.3	L700N	Pathogenic	0.99
OPA1	O60313-1.3	L700P	Pathogenic	0.997
OPA1	O60313-1.3	L700Q	Pathogenic	0.981
OPA1	O60313-1.3	L700R	Pathogenic	0.96
OPA1	O60313-1.3	L700S	Pathogenic	0.981
OPA1	O60313-1.3	L700T	Pathogenic	0.962
OPA1	O60313-1.3	L700V	Pathogenic	0.884
OPA1	O60313-1.3	L700W	Pathogenic	0.994
OPA1	O60313-1.3	L700Y	Pathogenic	0.981
OPA1	O60313-1.3	K701A	Pathogenic	0.965
OPA1	O60313-1.3	K701C	Pathogenic	0.993
OPA1	O60313-1.3	K701D	Pathogenic	0.988
OPA1	O60313-1.3	K701E	Pathogenic	0.902
OPA1	O60313-1.3	K701F	Pathogenic	0.987
OPA1	O60313-1.3	K701G	Pathogenic	0.99
OPA1	O60313-1.3	K701H	Pathogenic	0.975
OPA1	O60313-1.3	K701I	Pathogenic	0.987
OPA1	O60313-1.3	K701L	Pathogenic	0.965
OPA1	O60313-1.3	K701M	Pathogenic	0.937
OPA1	O60313-1.3	K701N	Pathogenic	0.961
OPA1	O60313-1.3	K701P	Pathogenic	0.954
OPA1	O60313-1.3	K701Q	Pathogenic	0.865
OPA1	O60313-1.3	K701R	Pathogenic	0.819
OPA1	O60313-1.3	K701S	Pathogenic	0.931
OPA1	O60313-1.3	K701T	Pathogenic	0.97
OPA1	O60313-1.3	K701V	Pathogenic	0.976
OPA1	O60313-1.3	K701W	Pathogenic	0.979
OPA1	O60313-1.3	K701Y	Pathogenic	0.982
OPA1	O60313-1.3	E702A	Neutral	0.087
OPA1	O60313-1.3	E702C	Pathogenic	0.575
OPA1	O60313-1.3	E702D	Neutral	0.009
OPA1	O60313-1.3	E702F	Neutral	0.181
OPA1	O60313-1.3	E702G	Neutral	0.255
OPA1	O60313-1.3	E702H	Neutral	0.042
OPA1	O60313-1.3	E702I	Neutral	0.185
OPA1	O60313-1.3	E702K	Neutral	0.02
OPA1	O60313-1.3	E702L	Neutral	0.199
OPA1	O60313-1.3	E702M	Neutral	0.116
OPA1	O60313-1.3	E702N	Neutral	0.078
OPA1	O60313-1.3	E702P	Neutral	0.067
OPA1	O60313-1.3	E702Q	Neutral	0.007
OPA1	O60313-1.3	E702R	Neutral	0.054
OPA1	O60313-1.3	E702S	Neutral	0.044
OPA1	O60313-1.3	E702T	Neutral	0.1
OPA1	O60313-1.3	E702V	Neutral	0.122
OPA1	O60313-1.3	E702W	Neutral	0.115
OPA1	O60313-1.3	E702Y	Neutral	0.137
OPA1	O60313-1.3	A703C	Pathogenic	0.954
OPA1	O60313-1.3	A703D	Pathogenic	0.992
OPA1	O60313-1.3	A703E	Pathogenic	0.977
OPA1	O60313-1.3	A703F	Pathogenic	0.986
OPA1	O60313-1.3	A703G	Pathogenic	0.966
OPA1	O60313-1.3	A703H	Pathogenic	0.996
OPA1	O60313-1.3	A703I	Pathogenic	0.961
OPA1	O60313-1.3	A703K	Pathogenic	0.966
OPA1	O60313-1.3	A703L	Pathogenic	0.964
OPA1	O60313-1.3	A703M	Pathogenic	0.976
OPA1	O60313-1.3	A703N	Pathogenic	0.993
OPA1	O60313-1.3	A703P	Pathogenic	0.987
OPA1	O60313-1.3	A703Q	Pathogenic	0.984
OPA1	O60313-1.3	A703R	Pathogenic	0.963
OPA1	O60313-1.3	A703S	Pathogenic	0.91
OPA1	O60313-1.3	A703T	Pathogenic	0.973
OPA1	O60313-1.3	A703V	Pathogenic	0.939
OPA1	O60313-1.3	A703W	Pathogenic	0.992
OPA1	O60313-1.3	A703Y	Pathogenic	0.993
OPA1	O60313-1.3	V704A	Pathogenic	0.945
OPA1	O60313-1.3	V704C	Pathogenic	0.99
OPA1	O60313-1.3	V704D	Pathogenic	0.994
OPA1	O60313-1.3	V704E	Pathogenic	0.986
OPA1	O60313-1.3	V704F	Pathogenic	0.986
OPA1	O60313-1.3	V704G	Pathogenic	0.997
OPA1	O60313-1.3	V704H	Pathogenic	0.997
OPA1	O60313-1.3	V704I	Pathogenic	0.503
OPA1	O60313-1.3	V704K	Pathogenic	0.978
OPA1	O60313-1.3	V704L	Pathogenic	0.903
OPA1	O60313-1.3	V704M	Pathogenic	0.935
OPA1	O60313-1.3	V704N	Pathogenic	0.995
OPA1	O60313-1.3	V704P	Pathogenic	0.996
OPA1	O60313-1.3	V704Q	Pathogenic	0.99
OPA1	O60313-1.3	V704R	Pathogenic	0.992
OPA1	O60313-1.3	V704S	Pathogenic	0.991
OPA1	O60313-1.3	V704T	Pathogenic	0.947
OPA1	O60313-1.3	V704W	Pathogenic	0.997
OPA1	O60313-1.3	V704Y	Pathogenic	0.989
OPA1	O60313-1.3	K705A	Pathogenic	0.604
OPA1	O60313-1.3	K705C	Pathogenic	0.881
OPA1	O60313-1.3	K705D	Pathogenic	0.817
OPA1	O60313-1.3	K705E	Neutral	0.335
OPA1	O60313-1.3	K705F	Pathogenic	0.81
OPA1	O60313-1.3	K705G	Pathogenic	0.845
OPA1	O60313-1.3	K705H	Pathogenic	0.684
OPA1	O60313-1.3	K705I	Pathogenic	0.801
OPA1	O60313-1.3	K705L	Pathogenic	0.604
OPA1	O60313-1.3	K705M	Neutral	0.447
OPA1	O60313-1.3	K705N	Pathogenic	0.574
OPA1	O60313-1.3	K705P	Pathogenic	0.533
OPA1	O60313-1.3	K705Q	Neutral	0.259
OPA1	O60313-1.3	K705R	Neutral	0.199
OPA1	O60313-1.3	K705S	Neutral	0.424
OPA1	O60313-1.3	K705T	Pathogenic	0.638
OPA1	O60313-1.3	K705V	Pathogenic	0.689
OPA1	O60313-1.3	K705W	Pathogenic	0.715
OPA1	O60313-1.3	K705Y	Pathogenic	0.754
OPA1	O60313-1.3	E706A	Neutral	0.131
OPA1	O60313-1.3	E706C	Pathogenic	0.68
OPA1	O60313-1.3	E706D	Neutral	0.014
OPA1	O60313-1.3	E706F	Neutral	0.258
OPA1	O60313-1.3	E706G	Neutral	0.351
OPA1	O60313-1.3	E706H	Neutral	0.065
OPA1	O60313-1.3	E706I	Neutral	0.263
OPA1	O60313-1.3	E706K	Neutral	0.032
OPA1	O60313-1.3	E706L	Neutral	0.281
OPA1	O60313-1.3	E706M	Neutral	0.172
OPA1	O60313-1.3	E706N	Neutral	0.118
OPA1	O60313-1.3	E706P	Neutral	0.101
OPA1	O60313-1.3	E706Q	Neutral	0.011
OPA1	O60313-1.3	E706R	Neutral	0.082
OPA1	O60313-1.3	E706S	Neutral	0.068
OPA1	O60313-1.3	E706T	Neutral	0.148
OPA1	O60313-1.3	E706V	Neutral	0.18
OPA1	O60313-1.3	E706W	Neutral	0.17
OPA1	O60313-1.3	E706Y	Neutral	0.2
OPA1	O60313-1.3	E707A	Pathogenic	0.964
OPA1	O60313-1.3	E707C	Pathogenic	0.997
OPA1	O60313-1.3	E707D	Pathogenic	0.719
OPA1	O60313-1.3	E707F	Pathogenic	0.984
OPA1	O60313-1.3	E707G	Pathogenic	0.99
OPA1	O60313-1.3	E707H	Pathogenic	0.925
OPA1	O60313-1.3	E707I	Pathogenic	0.985
OPA1	O60313-1.3	E707K	Pathogenic	0.855
OPA1	O60313-1.3	E707L	Pathogenic	0.986
OPA1	O60313-1.3	E707M	Pathogenic	0.974
OPA1	O60313-1.3	E707N	Pathogenic	0.96
OPA1	O60313-1.3	E707P	Pathogenic	0.953
OPA1	O60313-1.3	E707Q	Pathogenic	0.674
OPA1	O60313-1.3	E707R	Pathogenic	0.941
OPA1	O60313-1.3	E707S	Pathogenic	0.929
OPA1	O60313-1.3	E707T	Pathogenic	0.969
OPA1	O60313-1.3	E707V	Pathogenic	0.975
OPA1	O60313-1.3	E707W	Pathogenic	0.974
OPA1	O60313-1.3	E707Y	Pathogenic	0.978
OPA1	O60313-1.3	S708A	Neutral	0.085
OPA1	O60313-1.3	S708C	Neutral	0.291
OPA1	O60313-1.3	S708D	Neutral	0.153
OPA1	O60313-1.3	S708E	Neutral	0.16
OPA1	O60313-1.3	S708F	Neutral	0.321
OPA1	O60313-1.3	S708G	Neutral	0.249
OPA1	O60313-1.3	S708H	Neutral	0.442
OPA1	O60313-1.3	S708I	Neutral	0.327
OPA1	O60313-1.3	S708K	Neutral	0.111
OPA1	O60313-1.3	S708L	Neutral	0.348
OPA1	O60313-1.3	S708M	Neutral	0.221
OPA1	O60313-1.3	S708N	Neutral	0.066
OPA1	O60313-1.3	S708P	Neutral	0.34
OPA1	O60313-1.3	S708Q	Neutral	0.215
OPA1	O60313-1.3	S708R	Neutral	0.254
OPA1	O60313-1.3	S708T	Neutral	0.085
OPA1	O60313-1.3	S708V	Neutral	0.472
OPA1	O60313-1.3	S708W	Neutral	0.447
OPA1	O60313-1.3	S708Y	Neutral	0.497
OPA1	O60313-1.3	I709A	Pathogenic	0.547
OPA1	O60313-1.3	I709C	Pathogenic	0.706
OPA1	O60313-1.3	I709D	Pathogenic	0.805
OPA1	O60313-1.3	I709E	Pathogenic	0.833
OPA1	O60313-1.3	I709F	Pathogenic	0.657
OPA1	O60313-1.3	I709G	Pathogenic	0.954
OPA1	O60313-1.3	I709H	Pathogenic	0.913
OPA1	O60313-1.3	I709K	Pathogenic	0.786
OPA1	O60313-1.3	I709L	Neutral	0.18
OPA1	O60313-1.3	I709M	Neutral	0.293
OPA1	O60313-1.3	I709N	Pathogenic	0.831
OPA1	O60313-1.3	I709P	Pathogenic	0.941
OPA1	O60313-1.3	I709Q	Pathogenic	0.882
OPA1	O60313-1.3	I709R	Pathogenic	0.775
OPA1	O60313-1.3	I709S	Pathogenic	0.723
OPA1	O60313-1.3	I709T	Pathogenic	0.559
OPA1	O60313-1.3	I709V	Neutral	0.043
OPA1	O60313-1.3	I709W	Pathogenic	0.966
OPA1	O60313-1.3	I709Y	Pathogenic	0.718
OPA1	O60313-1.3	K710A	Pathogenic	0.509
OPA1	O60313-1.3	K710C	Pathogenic	0.835
OPA1	O60313-1.3	K710D	Pathogenic	0.753
OPA1	O60313-1.3	K710E	Neutral	0.256
OPA1	O60313-1.3	K710F	Pathogenic	0.744
OPA1	O60313-1.3	K710G	Pathogenic	0.788
OPA1	O60313-1.3	K710H	Pathogenic	0.596
OPA1	O60313-1.3	K710I	Pathogenic	0.733
OPA1	O60313-1.3	K710L	Pathogenic	0.51
OPA1	O60313-1.3	K710M	Neutral	0.355
OPA1	O60313-1.3	K710N	Neutral	0.478
OPA1	O60313-1.3	K710P	Neutral	0.437
OPA1	O60313-1.3	K710Q	Neutral	0.193
OPA1	O60313-1.3	K710R	Neutral	0.145
OPA1	O60313-1.3	K710S	Neutral	0.334
OPA1	O60313-1.3	K710T	Pathogenic	0.545
OPA1	O60313-1.3	K710V	Pathogenic	0.601
OPA1	O60313-1.3	K710W	Pathogenic	0.631
OPA1	O60313-1.3	K710Y	Pathogenic	0.676
OPA1	O60313-1.3	R711A	Pathogenic	0.948
OPA1	O60313-1.3	R711C	Pathogenic	0.989
OPA1	O60313-1.3	R711D	Pathogenic	0.994
OPA1	O60313-1.3	R711E	Pathogenic	0.946
OPA1	O60313-1.3	R711F	Pathogenic	0.981
OPA1	O60313-1.3	R711G	Pathogenic	0.985
OPA1	O60313-1.3	R711H	Pathogenic	0.899
OPA1	O60313-1.3	R711I	Pathogenic	0.98
OPA1	O60313-1.3	R711K	Pathogenic	0.759
OPA1	O60313-1.3	R711L	Pathogenic	0.948
OPA1	O60313-1.3	R711M	Pathogenic	0.906
OPA1	O60313-1.3	R711N	Pathogenic	0.941
OPA1	O60313-1.3	R711P	Pathogenic	0.975
OPA1	O60313-1.3	R711Q	Pathogenic	0.807
OPA1	O60313-1.3	R711S	Pathogenic	0.962
OPA1	O60313-1.3	R711T	Pathogenic	0.954
OPA1	O60313-1.3	R711V	Pathogenic	0.987
OPA1	O60313-1.3	R711W	Pathogenic	0.971
OPA1	O60313-1.3	R711Y	Pathogenic	0.974
OPA1	O60313-1.3	H712A	Pathogenic	0.997
OPA1	O60313-1.3	H712C	Pathogenic	0.998
OPA1	O60313-1.3	H712D	Pathogenic	0.987
OPA1	O60313-1.3	H712E	Pathogenic	0.969
OPA1	O60313-1.3	H712F	Pathogenic	0.975
OPA1	O60313-1.3	H712G	Pathogenic	0.997
OPA1	O60313-1.3	H712I	Pathogenic	0.997
OPA1	O60313-1.3	H712K	Pathogenic	0.985
OPA1	O60313-1.3	H712L	Pathogenic	0.997
OPA1	O60313-1.3	H712M	Pathogenic	0.995
OPA1	O60313-1.3	H712N	Pathogenic	0.914
OPA1	O60313-1.3	H712P	Pathogenic	0.997
OPA1	O60313-1.3	H712Q	Pathogenic	0.979
OPA1	O60313-1.3	H712R	Pathogenic	0.954
OPA1	O60313-1.3	H712S	Pathogenic	0.993
OPA1	O60313-1.3	H712T	Pathogenic	0.998
OPA1	O60313-1.3	H712V	Pathogenic	0.998
OPA1	O60313-1.3	H712W	Pathogenic	0.985
OPA1	O60313-1.3	H712Y	Pathogenic	0.769
OPA1	O60313-1.3	K713A	Neutral	0.183
OPA1	O60313-1.3	K713C	Pathogenic	0.521
OPA1	O60313-1.3	K713D	Neutral	0.396
OPA1	O60313-1.3	K713E	Neutral	0.069
OPA1	O60313-1.3	K713F	Neutral	0.384
OPA1	O60313-1.3	K713G	Neutral	0.445
OPA1	O60313-1.3	K713H	Neutral	0.241
OPA1	O60313-1.3	K713I	Neutral	0.372
OPA1	O60313-1.3	K713L	Neutral	0.183
OPA1	O60313-1.3	K713M	Neutral	0.106
OPA1	O60313-1.3	K713N	Neutral	0.165
OPA1	O60313-1.3	K713P	Neutral	0.143
OPA1	O60313-1.3	K713Q	Neutral	0.049
OPA1	O60313-1.3	K713R	Neutral	0.035
OPA1	O60313-1.3	K713S	Neutral	0.098
OPA1	O60313-1.3	K713T	Neutral	0.205
OPA1	O60313-1.3	K713V	Neutral	0.245
OPA1	O60313-1.3	K713W	Neutral	0.269
OPA1	O60313-1.3	K713Y	Neutral	0.31
OPA1	O60313-1.3	W714A	Pathogenic	0.995
OPA1	O60313-1.3	W714C	Pathogenic	0.993
OPA1	O60313-1.3	W714D	Pathogenic	0.996
OPA1	O60313-1.3	W714E	Pathogenic	0.991
OPA1	O60313-1.3	W714F	Pathogenic	0.94
OPA1	O60313-1.3	W714G	Pathogenic	0.982
OPA1	O60313-1.3	W714H	Pathogenic	0.987
OPA1	O60313-1.3	W714I	Pathogenic	0.999
OPA1	O60313-1.3	W714K	Pathogenic	0.989
OPA1	O60313-1.3	W714L	Pathogenic	0.997
OPA1	O60313-1.3	W714M	Pathogenic	0.987
OPA1	O60313-1.3	W714N	Pathogenic	0.997
OPA1	O60313-1.3	W714P	Pathogenic	0.999
OPA1	O60313-1.3	W714Q	Pathogenic	0.982
OPA1	O60313-1.3	W714R	Pathogenic	0.989
OPA1	O60313-1.3	W714S	Pathogenic	0.994
OPA1	O60313-1.3	W714T	Pathogenic	0.988
OPA1	O60313-1.3	W714V	Pathogenic	0.998
OPA1	O60313-1.3	W714Y	Pathogenic	0.72
OPA1	O60313-1.3	N715A	Pathogenic	0.926
OPA1	O60313-1.3	N715C	Pathogenic	0.955
OPA1	O60313-1.3	N715D	Pathogenic	0.526
OPA1	O60313-1.3	N715E	Pathogenic	0.779
OPA1	O60313-1.3	N715F	Pathogenic	0.9
OPA1	O60313-1.3	N715G	Pathogenic	0.648
OPA1	O60313-1.3	N715H	Neutral	0.383
OPA1	O60313-1.3	N715I	Pathogenic	0.903
OPA1	O60313-1.3	N715K	Pathogenic	0.698
OPA1	O60313-1.3	N715L	Pathogenic	0.911
OPA1	O60313-1.3	N715M	Pathogenic	0.844
OPA1	O60313-1.3	N715P	Pathogenic	0.904
OPA1	O60313-1.3	N715Q	Pathogenic	0.716
OPA1	O60313-1.3	N715R	Pathogenic	0.685
OPA1	O60313-1.3	N715S	Neutral	0.419
OPA1	O60313-1.3	N715T	Pathogenic	0.633
OPA1	O60313-1.3	N715V	Pathogenic	0.945
OPA1	O60313-1.3	N715W	Pathogenic	0.939
OPA1	O60313-1.3	N715Y	Pathogenic	0.867
OPA1	O60313-1.3	D716A	Pathogenic	0.712
OPA1	O60313-1.3	D716C	Pathogenic	0.805
OPA1	O60313-1.3	D716E	Neutral	0.078
OPA1	O60313-1.3	D716F	Pathogenic	0.631
OPA1	O60313-1.3	D716G	Pathogenic	0.512
OPA1	O60313-1.3	D716H	Neutral	0.497
OPA1	O60313-1.3	D716I	Pathogenic	0.638
OPA1	O60313-1.3	D716K	Pathogenic	0.634
OPA1	O60313-1.3	D716L	Pathogenic	0.849
OPA1	O60313-1.3	D716M	Pathogenic	0.748
OPA1	O60313-1.3	D716N	Neutral	0.2
OPA1	O60313-1.3	D716P	Neutral	0.389
OPA1	O60313-1.3	D716Q	Neutral	0.323
OPA1	O60313-1.3	D716R	Pathogenic	0.825
OPA1	O60313-1.3	D716S	Neutral	0.291
OPA1	O60313-1.3	D716T	Neutral	0.492
OPA1	O60313-1.3	D716V	Pathogenic	0.764
OPA1	O60313-1.3	D716W	Pathogenic	0.745
OPA1	O60313-1.3	D716Y	Pathogenic	0.781
OPA1	O60313-1.3	F717A	Neutral	0.11
OPA1	O60313-1.3	F717C	Neutral	0.197
OPA1	O60313-1.3	F717D	Neutral	0.127
OPA1	O60313-1.3	F717E	Neutral	0.15
OPA1	O60313-1.3	F717G	Neutral	0.201
OPA1	O60313-1.3	F717H	Neutral	0.042
OPA1	O60313-1.3	F717I	Neutral	0.065
OPA1	O60313-1.3	F717K	Neutral	0.123
OPA1	O60313-1.3	F717L	Neutral	0.061
OPA1	O60313-1.3	F717M	Neutral	0.041
OPA1	O60313-1.3	F717N	Neutral	0.148
OPA1	O60313-1.3	F717P	Pathogenic	0.622
OPA1	O60313-1.3	F717Q	Neutral	0.208
OPA1	O60313-1.3	F717R	Neutral	0.117
OPA1	O60313-1.3	F717S	Neutral	0.084
OPA1	O60313-1.3	F717T	Neutral	0.115
OPA1	O60313-1.3	F717V	Neutral	0.101
OPA1	O60313-1.3	F717W	Neutral	0.015
OPA1	O60313-1.3	F717Y	Neutral	0.001
OPA1	O60313-1.3	A718C	Pathogenic	0.909
OPA1	O60313-1.3	A718D	Pathogenic	0.983
OPA1	O60313-1.3	A718E	Pathogenic	0.954
OPA1	O60313-1.3	A718F	Pathogenic	0.971
OPA1	O60313-1.3	A718G	Pathogenic	0.933
OPA1	O60313-1.3	A718H	Pathogenic	0.992
OPA1	O60313-1.3	A718I	Pathogenic	0.922
OPA1	O60313-1.3	A718K	Pathogenic	0.931
OPA1	O60313-1.3	A718L	Pathogenic	0.928
OPA1	O60313-1.3	A718M	Pathogenic	0.952
OPA1	O60313-1.3	A718N	Pathogenic	0.985
OPA1	O60313-1.3	A718P	Pathogenic	0.973
OPA1	O60313-1.3	A718Q	Pathogenic	0.967
OPA1	O60313-1.3	A718R	Pathogenic	0.927
OPA1	O60313-1.3	A718S	Pathogenic	0.83
OPA1	O60313-1.3	A718T	Pathogenic	0.945
OPA1	O60313-1.3	A718V	Pathogenic	0.882
OPA1	O60313-1.3	A718W	Pathogenic	0.983
OPA1	O60313-1.3	A718Y	Pathogenic	0.986
OPA1	O60313-1.3	E719A	Neutral	0.056
OPA1	O60313-1.3	E719C	Neutral	0.454
OPA1	O60313-1.3	E719D	Neutral	0.006
OPA1	O60313-1.3	E719F	Neutral	0.12
OPA1	O60313-1.3	E719G	Neutral	0.174
OPA1	O60313-1.3	E719H	Neutral	0.026
OPA1	O60313-1.3	E719I	Neutral	0.122
OPA1	O60313-1.3	E719K	Neutral	0.013
OPA1	O60313-1.3	E719L	Neutral	0.133
OPA1	O60313-1.3	E719M	Neutral	0.075
OPA1	O60313-1.3	E719N	Neutral	0.05
OPA1	O60313-1.3	E719P	Neutral	0.042
OPA1	O60313-1.3	E719Q	Neutral	0.004
OPA1	O60313-1.3	E719R	Neutral	0.034
OPA1	O60313-1.3	E719S	Neutral	0.028
OPA1	O60313-1.3	E719T	Neutral	0.064
OPA1	O60313-1.3	E719V	Neutral	0.079
OPA1	O60313-1.3	E719W	Neutral	0.074
OPA1	O60313-1.3	E719Y	Neutral	0.089
OPA1	O60313-1.3	D720A	Pathogenic	0.945
OPA1	O60313-1.3	D720C	Pathogenic	0.967
OPA1	O60313-1.3	D720E	Neutral	0.372
OPA1	O60313-1.3	D720F	Pathogenic	0.923
OPA1	O60313-1.3	D720G	Pathogenic	0.88
OPA1	O60313-1.3	D720H	Pathogenic	0.873
OPA1	O60313-1.3	D720I	Pathogenic	0.925
OPA1	O60313-1.3	D720K	Pathogenic	0.923
OPA1	O60313-1.3	D720L	Pathogenic	0.975
OPA1	O60313-1.3	D720M	Pathogenic	0.954
OPA1	O60313-1.3	D720N	Pathogenic	0.635
OPA1	O60313-1.3	D720P	Pathogenic	0.816
OPA1	O60313-1.3	D720Q	Pathogenic	0.769
OPA1	O60313-1.3	D720R	Pathogenic	0.97
OPA1	O60313-1.3	D720S	Pathogenic	0.741
OPA1	O60313-1.3	D720T	Pathogenic	0.871
OPA1	O60313-1.3	D720V	Pathogenic	0.957
OPA1	O60313-1.3	D720W	Pathogenic	0.953
OPA1	O60313-1.3	D720Y	Pathogenic	0.961
OPA1	O60313-1.3	S721A	Neutral	0.433
OPA1	O60313-1.3	S721C	Pathogenic	0.771
OPA1	O60313-1.3	S721D	Pathogenic	0.597
OPA1	O60313-1.3	S721E	Pathogenic	0.61
OPA1	O60313-1.3	S721F	Pathogenic	0.795
OPA1	O60313-1.3	S721G	Pathogenic	0.732
OPA1	O60313-1.3	S721H	Pathogenic	0.867
OPA1	O60313-1.3	S721I	Pathogenic	0.8
OPA1	O60313-1.3	S721K	Pathogenic	0.507
OPA1	O60313-1.3	S721L	Pathogenic	0.815
OPA1	O60313-1.3	S721M	Pathogenic	0.699
OPA1	O60313-1.3	S721N	Neutral	0.369
OPA1	O60313-1.3	S721P	Pathogenic	0.809
OPA1	O60313-1.3	S721Q	Pathogenic	0.692
OPA1	O60313-1.3	S721R	Pathogenic	0.737
OPA1	O60313-1.3	S721T	Neutral	0.431
OPA1	O60313-1.3	S721V	Pathogenic	0.88
OPA1	O60313-1.3	S721W	Pathogenic	0.869
OPA1	O60313-1.3	S721Y	Pathogenic	0.89
OPA1	O60313-1.3	L722A	Pathogenic	0.96
OPA1	O60313-1.3	L722C	Pathogenic	0.98
OPA1	O60313-1.3	L722D	Pathogenic	0.996
OPA1	O60313-1.3	L722E	Pathogenic	0.99
OPA1	O60313-1.3	L722F	Pathogenic	0.97
OPA1	O60313-1.3	L722G	Pathogenic	0.998
OPA1	O60313-1.3	L722H	Pathogenic	0.995
OPA1	O60313-1.3	L722I	Pathogenic	0.801
OPA1	O60313-1.3	L722K	Pathogenic	0.962
OPA1	O60313-1.3	L722M	Pathogenic	0.742
OPA1	O60313-1.3	L722N	Pathogenic	0.99
OPA1	O60313-1.3	L722P	Pathogenic	0.997
OPA1	O60313-1.3	L722Q	Pathogenic	0.981
OPA1	O60313-1.3	L722R	Pathogenic	0.96
OPA1	O60313-1.3	L722S	Pathogenic	0.981
OPA1	O60313-1.3	L722T	Pathogenic	0.962
OPA1	O60313-1.3	L722V	Pathogenic	0.884
OPA1	O60313-1.3	L722W	Pathogenic	0.994
OPA1	O60313-1.3	L722Y	Pathogenic	0.981
OPA1	O60313-1.3	R723A	Pathogenic	0.984
OPA1	O60313-1.3	R723C	Pathogenic	0.997
OPA1	O60313-1.3	R723D	Pathogenic	0.998
OPA1	O60313-1.3	R723E	Pathogenic	0.983
OPA1	O60313-1.3	R723F	Pathogenic	0.994
OPA1	O60313-1.3	R723G	Pathogenic	0.995
OPA1	O60313-1.3	R723H	Pathogenic	0.967
OPA1	O60313-1.3	R723I	Pathogenic	0.994
OPA1	O60313-1.3	R723K	Pathogenic	0.912
OPA1	O60313-1.3	R723L	Pathogenic	0.984
OPA1	O60313-1.3	R723M	Pathogenic	0.97
OPA1	O60313-1.3	R723N	Pathogenic	0.981
OPA1	O60313-1.3	R723P	Pathogenic	0.992
OPA1	O60313-1.3	R723Q	Pathogenic	0.932
OPA1	O60313-1.3	R723S	Pathogenic	0.988
OPA1	O60313-1.3	R723T	Pathogenic	0.986
OPA1	O60313-1.3	R723V	Pathogenic	0.996
OPA1	O60313-1.3	R723W	Pathogenic	0.991
OPA1	O60313-1.3	R723Y	Pathogenic	0.992
OPA1	O60313-1.3	V724A	Pathogenic	0.949
OPA1	O60313-1.3	V724C	Pathogenic	0.991
OPA1	O60313-1.3	V724D	Pathogenic	0.995
OPA1	O60313-1.3	V724E	Pathogenic	0.987
OPA1	O60313-1.3	V724F	Pathogenic	0.987
OPA1	O60313-1.3	V724G	Pathogenic	0.997
OPA1	O60313-1.3	V724H	Pathogenic	0.998
OPA1	O60313-1.3	V724I	Pathogenic	0.524
OPA1	O60313-1.3	V724K	Pathogenic	0.98
OPA1	O60313-1.3	V724L	Pathogenic	0.911
OPA1	O60313-1.3	V724M	Pathogenic	0.94
OPA1	O60313-1.3	V724N	Pathogenic	0.995
OPA1	O60313-1.3	V724P	Pathogenic	0.996
OPA1	O60313-1.3	V724Q	Pathogenic	0.991
OPA1	O60313-1.3	V724R	Pathogenic	0.993
OPA1	O60313-1.3	V724S	Pathogenic	0.992
OPA1	O60313-1.3	V724T	Pathogenic	0.951
OPA1	O60313-1.3	V724W	Pathogenic	0.997
OPA1	O60313-1.3	V724Y	Pathogenic	0.99
OPA1	O60313-1.3	I725A	Pathogenic	0.985
OPA1	O60313-1.3	I725C	Pathogenic	0.993
OPA1	O60313-1.3	I725D	Pathogenic	0.996
OPA1	O60313-1.3	I725E	Pathogenic	0.996
OPA1	O60313-1.3	I725F	Pathogenic	0.991
OPA1	O60313-1.3	I725G	Pathogenic	0.999
OPA1	O60313-1.3	I725H	Pathogenic	0.998
OPA1	O60313-1.3	I725K	Pathogenic	0.995
OPA1	O60313-1.3	I725L	Pathogenic	0.925
OPA1	O60313-1.3	I725M	Pathogenic	0.959
OPA1	O60313-1.3	I725N	Pathogenic	0.996
OPA1	O60313-1.3	I725P	Pathogenic	0.999
OPA1	O60313-1.3	I725Q	Pathogenic	0.998
OPA1	O60313-1.3	I725R	Pathogenic	0.995
OPA1	O60313-1.3	I725S	Pathogenic	0.993
OPA1	O60313-1.3	I725T	Pathogenic	0.986
OPA1	O60313-1.3	I725V	Pathogenic	0.717
OPA1	O60313-1.3	I725W	Pathogenic	0.999
OPA1	O60313-1.3	I725Y	Pathogenic	0.993
OPA1	O60313-1.3	Q726A	Pathogenic	0.994
OPA1	O60313-1.3	Q726C	Pathogenic	0.999
OPA1	O60313-1.3	Q726D	Pathogenic	0.984
OPA1	O60313-1.3	Q726E	Pathogenic	0.9
OPA1	O60313-1.3	Q726F	Pathogenic	0.998
OPA1	O60313-1.3	Q726G	Pathogenic	0.998
OPA1	O60313-1.3	Q726H	Pathogenic	0.988
OPA1	O60313-1.3	Q726I	Pathogenic	0.998
OPA1	O60313-1.3	Q726K	Pathogenic	0.947
OPA1	O60313-1.3	Q726L	Pathogenic	0.994
OPA1	O60313-1.3	Q726M	Pathogenic	0.967
OPA1	O60313-1.3	Q726N	Pathogenic	0.987
OPA1	O60313-1.3	Q726P	Pathogenic	0.992
OPA1	O60313-1.3	Q726R	Pathogenic	0.944
OPA1	O60313-1.3	Q726S	Pathogenic	0.988
OPA1	O60313-1.3	Q726T	Pathogenic	0.995
OPA1	O60313-1.3	Q726V	Pathogenic	0.996
OPA1	O60313-1.3	Q726W	Pathogenic	0.988
OPA1	O60313-1.3	Q726Y	Pathogenic	0.99
OPA1	O60313-1.3	H727A	Pathogenic	0.983
OPA1	O60313-1.3	H727C	Pathogenic	0.99
OPA1	O60313-1.3	H727D	Pathogenic	0.919
OPA1	O60313-1.3	H727E	Pathogenic	0.826
OPA1	O60313-1.3	H727F	Pathogenic	0.856
OPA1	O60313-1.3	H727G	Pathogenic	0.983
OPA1	O60313-1.3	H727I	Pathogenic	0.981
OPA1	O60313-1.3	H727K	Pathogenic	0.906
OPA1	O60313-1.3	H727L	Pathogenic	0.983
OPA1	O60313-1.3	H727M	Pathogenic	0.968
OPA1	O60313-1.3	H727N	Pathogenic	0.617
OPA1	O60313-1.3	H727P	Pathogenic	0.978
OPA1	O60313-1.3	H727Q	Pathogenic	0.876
OPA1	O60313-1.3	H727R	Pathogenic	0.758
OPA1	O60313-1.3	H727S	Pathogenic	0.954
OPA1	O60313-1.3	H727T	Pathogenic	0.985
OPA1	O60313-1.3	H727V	Pathogenic	0.988
OPA1	O60313-1.3	H727W	Pathogenic	0.91
OPA1	O60313-1.3	H727Y	Neutral	0.337
OPA1	O60313-1.3	N728A	Pathogenic	0.998
OPA1	O60313-1.3	N728C	Pathogenic	0.999
OPA1	O60313-1.3	N728D	Pathogenic	0.974
OPA1	O60313-1.3	N728E	Pathogenic	0.992
OPA1	O60313-1.3	N728F	Pathogenic	0.997
OPA1	O60313-1.3	N728G	Pathogenic	0.984
OPA1	O60313-1.3	N728H	Pathogenic	0.954
OPA1	O60313-1.3	N728I	Pathogenic	0.997
OPA1	O60313-1.3	N728K	Pathogenic	0.987
OPA1	O60313-1.3	N728L	Pathogenic	0.997
OPA1	O60313-1.3	N728M	Pathogenic	0.994
OPA1	O60313-1.3	N728P	Pathogenic	0.997
OPA1	O60313-1.3	N728Q	Pathogenic	0.988
OPA1	O60313-1.3	N728R	Pathogenic	0.986
OPA1	O60313-1.3	N728S	Pathogenic	0.96
OPA1	O60313-1.3	N728T	Pathogenic	0.983
OPA1	O60313-1.3	N728V	Pathogenic	0.998
OPA1	O60313-1.3	N728W	Pathogenic	0.998
OPA1	O60313-1.3	N728Y	Pathogenic	0.995
OPA1	O60313-1.3	A729C	Pathogenic	0.714
OPA1	O60313-1.3	A729D	Pathogenic	0.935
OPA1	O60313-1.3	A729E	Pathogenic	0.839
OPA1	O60313-1.3	A729F	Pathogenic	0.893
OPA1	O60313-1.3	A729G	Pathogenic	0.778
OPA1	O60313-1.3	A729H	Pathogenic	0.967
OPA1	O60313-1.3	A729I	Pathogenic	0.748
OPA1	O60313-1.3	A729K	Pathogenic	0.774
OPA1	O60313-1.3	A729L	Pathogenic	0.765
OPA1	O60313-1.3	A729M	Pathogenic	0.834
OPA1	O60313-1.3	A729N	Pathogenic	0.942
OPA1	O60313-1.3	A729P	Pathogenic	0.901
OPA1	O60313-1.3	A729Q	Pathogenic	0.882
OPA1	O60313-1.3	A729R	Pathogenic	0.762
OPA1	O60313-1.3	A729S	Pathogenic	0.551
OPA1	O60313-1.3	A729T	Pathogenic	0.812
OPA1	O60313-1.3	A729V	Pathogenic	0.653
OPA1	O60313-1.3	A729W	Pathogenic	0.935
OPA1	O60313-1.3	A729Y	Pathogenic	0.946
OPA1	O60313-1.3	L730A	Pathogenic	0.982
OPA1	O60313-1.3	L730C	Pathogenic	0.991
OPA1	O60313-1.3	L730D	Pathogenic	0.998
OPA1	O60313-1.3	L730E	Pathogenic	0.996
OPA1	O60313-1.3	L730F	Pathogenic	0.987
OPA1	O60313-1.3	L730G	Pathogenic	0.999
OPA1	O60313-1.3	L730H	Pathogenic	0.998
OPA1	O60313-1.3	L730I	Pathogenic	0.902
OPA1	O60313-1.3	L730K	Pathogenic	0.983
OPA1	O60313-1.3	L730M	Pathogenic	0.868
OPA1	O60313-1.3	L730N	Pathogenic	0.996
OPA1	O60313-1.3	L730P	Pathogenic	0.999
OPA1	O60313-1.3	L730Q	Pathogenic	0.992
OPA1	O60313-1.3	L730R	Pathogenic	0.982
OPA1	O60313-1.3	L730S	Pathogenic	0.992
OPA1	O60313-1.3	L730T	Pathogenic	0.983
OPA1	O60313-1.3	L730V	Pathogenic	0.946
OPA1	O60313-1.3	L730W	Pathogenic	0.997
OPA1	O60313-1.3	L730Y	Pathogenic	0.992
OPA1	O60313-1.3	E731A	Pathogenic	0.99
OPA1	O60313-1.3	E731C	Pathogenic	0.999
OPA1	O60313-1.3	E731D	Pathogenic	0.9
OPA1	O60313-1.3	E731F	Pathogenic	0.995
OPA1	O60313-1.3	E731G	Pathogenic	0.997
OPA1	O60313-1.3	E731H	Pathogenic	0.978
OPA1	O60313-1.3	E731I	Pathogenic	0.996
OPA1	O60313-1.3	E731K	Pathogenic	0.954
OPA1	O60313-1.3	E731L	Pathogenic	0.996
OPA1	O60313-1.3	E731M	Pathogenic	0.992
OPA1	O60313-1.3	E731N	Pathogenic	0.988
OPA1	O60313-1.3	E731P	Pathogenic	0.986
OPA1	O60313-1.3	E731Q	Pathogenic	0.88
OPA1	O60313-1.3	E731R	Pathogenic	0.983
OPA1	O60313-1.3	E731S	Pathogenic	0.979
OPA1	O60313-1.3	E731T	Pathogenic	0.991
OPA1	O60313-1.3	E731V	Pathogenic	0.993
OPA1	O60313-1.3	E731W	Pathogenic	0.992
OPA1	O60313-1.3	E731Y	Pathogenic	0.994
OPA1	O60313-1.3	D732A	Pathogenic	0.996
OPA1	O60313-1.3	D732C	Pathogenic	0.998
OPA1	O60313-1.3	D732E	Pathogenic	0.896
OPA1	O60313-1.3	D732F	Pathogenic	0.994
OPA1	O60313-1.3	D732G	Pathogenic	0.991
OPA1	O60313-1.3	D732H	Pathogenic	0.99
OPA1	O60313-1.3	D732I	Pathogenic	0.994
OPA1	O60313-1.3	D732K	Pathogenic	0.994
OPA1	O60313-1.3	D732L	Pathogenic	0.998
OPA1	O60313-1.3	D732M	Pathogenic	0.997
OPA1	O60313-1.3	D732N	Pathogenic	0.962
OPA1	O60313-1.3	D732P	Pathogenic	0.985
OPA1	O60313-1.3	D732Q	Pathogenic	0.98
OPA1	O60313-1.3	D732R	Pathogenic	0.998
OPA1	O60313-1.3	D732S	Pathogenic	0.977
OPA1	O60313-1.3	D732T	Pathogenic	0.99
OPA1	O60313-1.3	D732V	Pathogenic	0.997
OPA1	O60313-1.3	D732W	Pathogenic	0.997
OPA1	O60313-1.3	D732Y	Pathogenic	0.997
OPA1	O60313-1.3	R733A	Pathogenic	0.985
OPA1	O60313-1.3	R733C	Pathogenic	0.997
OPA1	O60313-1.3	R733D	Pathogenic	0.998
OPA1	O60313-1.3	R733E	Pathogenic	0.985
OPA1	O60313-1.3	R733F	Pathogenic	0.995
OPA1	O60313-1.3	R733G	Pathogenic	0.996
OPA1	O60313-1.3	R733H	Pathogenic	0.97
OPA1	O60313-1.3	R733I	Pathogenic	0.994
OPA1	O60313-1.3	R733K	Pathogenic	0.921
OPA1	O60313-1.3	R733L	Pathogenic	0.985
OPA1	O60313-1.3	R733M	Pathogenic	0.973
OPA1	O60313-1.3	R733N	Pathogenic	0.983
OPA1	O60313-1.3	R733P	Pathogenic	0.993
OPA1	O60313-1.3	R733Q	Pathogenic	0.939
OPA1	O60313-1.3	R733S	Pathogenic	0.989
OPA1	O60313-1.3	R733T	Pathogenic	0.987
OPA1	O60313-1.3	R733V	Pathogenic	0.996
OPA1	O60313-1.3	R733W	Pathogenic	0.992
OPA1	O60313-1.3	R733Y	Pathogenic	0.993
OPA1	O60313-1.3	S734A	Pathogenic	0.816
OPA1	O60313-1.3	S734C	Pathogenic	0.951
OPA1	O60313-1.3	S734D	Pathogenic	0.896
OPA1	O60313-1.3	S734E	Pathogenic	0.901
OPA1	O60313-1.3	S734F	Pathogenic	0.958
OPA1	O60313-1.3	S734G	Pathogenic	0.941
OPA1	O60313-1.3	S734H	Pathogenic	0.974
OPA1	O60313-1.3	S734I	Pathogenic	0.959
OPA1	O60313-1.3	S734K	Pathogenic	0.857
OPA1	O60313-1.3	S734L	Pathogenic	0.962
OPA1	O60313-1.3	S734M	Pathogenic	0.931
OPA1	O60313-1.3	S734N	Pathogenic	0.773
OPA1	O60313-1.3	S734P	Pathogenic	0.961
OPA1	O60313-1.3	S734Q	Pathogenic	0.929
OPA1	O60313-1.3	S734R	Pathogenic	0.942
OPA1	O60313-1.3	S734T	Pathogenic	0.815
OPA1	O60313-1.3	S734V	Pathogenic	0.977
OPA1	O60313-1.3	S734W	Pathogenic	0.975
OPA1	O60313-1.3	S734Y	Pathogenic	0.979
OPA1	O60313-1.3	I735A	Pathogenic	0.817
OPA1	O60313-1.3	I735C	Pathogenic	0.899
OPA1	O60313-1.3	I735D	Pathogenic	0.939
OPA1	O60313-1.3	I735E	Pathogenic	0.949
OPA1	O60313-1.3	I735F	Pathogenic	0.877
OPA1	O60313-1.3	I735G	Pathogenic	0.987
OPA1	O60313-1.3	I735H	Pathogenic	0.975
OPA1	O60313-1.3	I735K	Pathogenic	0.932
OPA1	O60313-1.3	I735L	Neutral	0.449
OPA1	O60313-1.3	I735M	Pathogenic	0.606
OPA1	O60313-1.3	I735N	Pathogenic	0.948
OPA1	O60313-1.3	I735P	Pathogenic	0.984
OPA1	O60313-1.3	I735Q	Pathogenic	0.965
OPA1	O60313-1.3	I735R	Pathogenic	0.928
OPA1	O60313-1.3	I735S	Pathogenic	0.906
OPA1	O60313-1.3	I735T	Pathogenic	0.825
OPA1	O60313-1.3	I735V	Neutral	0.144
OPA1	O60313-1.3	I735W	Pathogenic	0.991
OPA1	O60313-1.3	I735Y	Pathogenic	0.904
OPA1	O60313-1.3	S736A	Neutral	0.07
OPA1	O60313-1.3	S736C	Neutral	0.25
OPA1	O60313-1.3	S736D	Neutral	0.128
OPA1	O60313-1.3	S736E	Neutral	0.134
OPA1	O60313-1.3	S736F	Neutral	0.278
OPA1	O60313-1.3	S736G	Neutral	0.213
OPA1	O60313-1.3	S736H	Neutral	0.392
OPA1	O60313-1.3	S736I	Neutral	0.283
OPA1	O60313-1.3	S736K	Neutral	0.092
OPA1	O60313-1.3	S736L	Neutral	0.303
OPA1	O60313-1.3	S736M	Neutral	0.187
OPA1	O60313-1.3	S736N	Neutral	0.055
OPA1	O60313-1.3	S736P	Neutral	0.295
OPA1	O60313-1.3	S736Q	Neutral	0.182
OPA1	O60313-1.3	S736R	Neutral	0.217
OPA1	O60313-1.3	S736T	Neutral	0.07
OPA1	O60313-1.3	S736V	Neutral	0.421
OPA1	O60313-1.3	S736W	Neutral	0.397
OPA1	O60313-1.3	S736Y	Neutral	0.445
OPA1	O60313-1.3	D737A	Pathogenic	0.997
OPA1	O60313-1.3	D737C	Pathogenic	0.998
OPA1	O60313-1.3	D737E	Pathogenic	0.914
OPA1	O60313-1.3	D737F	Pathogenic	0.995
OPA1	O60313-1.3	D737G	Pathogenic	0.992
OPA1	O60313-1.3	D737H	Pathogenic	0.992
OPA1	O60313-1.3	D737I	Pathogenic	0.995
OPA1	O60313-1.3	D737K	Pathogenic	0.995
OPA1	O60313-1.3	D737L	Pathogenic	0.999
OPA1	O60313-1.3	D737M	Pathogenic	0.997
OPA1	O60313-1.3	D737N	Pathogenic	0.969
OPA1	O60313-1.3	D737P	Pathogenic	0.988
OPA1	O60313-1.3	D737Q	Pathogenic	0.983
OPA1	O60313-1.3	D737R	Pathogenic	0.998
OPA1	O60313-1.3	D737S	Pathogenic	0.981
OPA1	O60313-1.3	D737T	Pathogenic	0.992
OPA1	O60313-1.3	D737V	Pathogenic	0.998
OPA1	O60313-1.3	D737W	Pathogenic	0.997
OPA1	O60313-1.3	D737Y	Pathogenic	0.998
OPA1	O60313-1.3	K738A	Pathogenic	0.985
OPA1	O60313-1.3	K738C	Pathogenic	0.997
OPA1	O60313-1.3	K738D	Pathogenic	0.995
OPA1	O60313-1.3	K738E	Pathogenic	0.955
OPA1	O60313-1.3	K738F	Pathogenic	0.994
OPA1	O60313-1.3	K738G	Pathogenic	0.996
OPA1	O60313-1.3	K738H	Pathogenic	0.989
OPA1	O60313-1.3	K738I	Pathogenic	0.994
OPA1	O60313-1.3	K738L	Pathogenic	0.985
OPA1	O60313-1.3	K738M	Pathogenic	0.971
OPA1	O60313-1.3	K738N	Pathogenic	0.983
OPA1	O60313-1.3	K738P	Pathogenic	0.98
OPA1	O60313-1.3	K738Q	Pathogenic	0.936
OPA1	O60313-1.3	K738R	Pathogenic	0.912
OPA1	O60313-1.3	K738S	Pathogenic	0.969
OPA1	O60313-1.3	K738T	Pathogenic	0.987
OPA1	O60313-1.3	K738V	Pathogenic	0.989
OPA1	O60313-1.3	K738W	Pathogenic	0.991
OPA1	O60313-1.3	K738Y	Pathogenic	0.992
OPA1	O60313-1.3	Q739A	Neutral	0.323
OPA1	O60313-1.3	Q739C	Pathogenic	0.699
OPA1	O60313-1.3	Q739D	Neutral	0.15
OPA1	O60313-1.3	Q739E	Neutral	0.025
OPA1	O60313-1.3	Q739F	Pathogenic	0.532
OPA1	O60313-1.3	Q739G	Pathogenic	0.631
OPA1	O60313-1.3	Q739H	Neutral	0.185
OPA1	O60313-1.3	Q739I	Pathogenic	0.539
OPA1	O60313-1.3	Q739K	Neutral	0.048
OPA1	O60313-1.3	Q739L	Neutral	0.307
OPA1	O60313-1.3	Q739M	Neutral	0.075
OPA1	O60313-1.3	Q739N	Neutral	0.173
OPA1	O60313-1.3	Q739P	Neutral	0.263
OPA1	O60313-1.3	Q739R	Neutral	0.045
OPA1	O60313-1.3	Q739S	Neutral	0.187
OPA1	O60313-1.3	Q739T	Neutral	0.355
OPA1	O60313-1.3	Q739V	Neutral	0.409
OPA1	O60313-1.3	Q739W	Neutral	0.188
OPA1	O60313-1.3	Q739Y	Neutral	0.22
OPA1	O60313-1.3	Q740A	Pathogenic	0.89
OPA1	O60313-1.3	Q740C	Pathogenic	0.975
OPA1	O60313-1.3	Q740D	Pathogenic	0.749
OPA1	O60313-1.3	Q740E	Neutral	0.3
OPA1	O60313-1.3	Q740F	Pathogenic	0.951
OPA1	O60313-1.3	Q740G	Pathogenic	0.967
OPA1	O60313-1.3	Q740H	Pathogenic	0.793
OPA1	O60313-1.3	Q740I	Pathogenic	0.952
OPA1	O60313-1.3	Q740K	Neutral	0.459
OPA1	O60313-1.3	Q740L	Pathogenic	0.882
OPA1	O60313-1.3	Q740M	Pathogenic	0.578
OPA1	O60313-1.3	Q740N	Pathogenic	0.78
OPA1	O60313-1.3	Q740P	Pathogenic	0.858
OPA1	O60313-1.3	Q740R	Neutral	0.444
OPA1	O60313-1.3	Q740S	Pathogenic	0.796
OPA1	O60313-1.3	Q740T	Pathogenic	0.903
OPA1	O60313-1.3	Q740V	Pathogenic	0.921
OPA1	O60313-1.3	Q740W	Pathogenic	0.797
OPA1	O60313-1.3	Q740Y	Pathogenic	0.827
OPA1	O60313-1.3	W741A	Pathogenic	0.998
OPA1	O60313-1.3	W741C	Pathogenic	0.997
OPA1	O60313-1.3	W741D	Pathogenic	0.998
OPA1	O60313-1.3	W741E	Pathogenic	0.996
OPA1	O60313-1.3	W741F	Pathogenic	0.973
OPA1	O60313-1.3	W741G	Pathogenic	0.992
OPA1	O60313-1.3	W741H	Pathogenic	0.994
OPA1	O60313-1.3	W741I	Pathogenic	1.0
OPA1	O60313-1.3	W741K	Pathogenic	0.995
OPA1	O60313-1.3	W741L	Pathogenic	0.999
OPA1	O60313-1.3	W741M	Pathogenic	0.994
OPA1	O60313-1.3	W741N	Pathogenic	0.999
OPA1	O60313-1.3	W741P	Pathogenic	1.0
OPA1	O60313-1.3	W741Q	Pathogenic	0.992
OPA1	O60313-1.3	W741R	Pathogenic	0.995
OPA1	O60313-1.3	W741S	Pathogenic	0.997
OPA1	O60313-1.3	W741T	Pathogenic	0.995
OPA1	O60313-1.3	W741V	Pathogenic	0.999
OPA1	O60313-1.3	W741Y	Pathogenic	0.855
OPA1	O60313-1.3	D742A	Pathogenic	0.997
OPA1	O60313-1.3	D742C	Pathogenic	0.998
OPA1	O60313-1.3	D742E	Pathogenic	0.914
OPA1	O60313-1.3	D742F	Pathogenic	0.995
OPA1	O60313-1.3	D742G	Pathogenic	0.992
OPA1	O60313-1.3	D742H	Pathogenic	0.992
OPA1	O60313-1.3	D742I	Pathogenic	0.995
OPA1	O60313-1.3	D742K	Pathogenic	0.995
OPA1	O60313-1.3	D742L	Pathogenic	0.999
OPA1	O60313-1.3	D742M	Pathogenic	0.997
OPA1	O60313-1.3	D742N	Pathogenic	0.969
OPA1	O60313-1.3	D742P	Pathogenic	0.988
OPA1	O60313-1.3	D742Q	Pathogenic	0.983
OPA1	O60313-1.3	D742R	Pathogenic	0.998
OPA1	O60313-1.3	D742S	Pathogenic	0.981
OPA1	O60313-1.3	D742T	Pathogenic	0.992
OPA1	O60313-1.3	D742V	Pathogenic	0.998
OPA1	O60313-1.3	D742W	Pathogenic	0.997
OPA1	O60313-1.3	D742Y	Pathogenic	0.998
OPA1	O60313-1.3	A743C	Pathogenic	0.731
OPA1	O60313-1.3	A743D	Pathogenic	0.939
OPA1	O60313-1.3	A743E	Pathogenic	0.849
OPA1	O60313-1.3	A743F	Pathogenic	0.901
OPA1	O60313-1.3	A743G	Pathogenic	0.792
OPA1	O60313-1.3	A743H	Pathogenic	0.97
OPA1	O60313-1.3	A743I	Pathogenic	0.763
OPA1	O60313-1.3	A743K	Pathogenic	0.788
OPA1	O60313-1.3	A743L	Pathogenic	0.78
OPA1	O60313-1.3	A743M	Pathogenic	0.845
OPA1	O60313-1.3	A743N	Pathogenic	0.947
OPA1	O60313-1.3	A743P	Pathogenic	0.908
OPA1	O60313-1.3	A743Q	Pathogenic	0.89
OPA1	O60313-1.3	A743R	Pathogenic	0.777
OPA1	O60313-1.3	A743S	Pathogenic	0.571
OPA1	O60313-1.3	A743T	Pathogenic	0.824
OPA1	O60313-1.3	A743V	Pathogenic	0.671
OPA1	O60313-1.3	A743W	Pathogenic	0.94
OPA1	O60313-1.3	A743Y	Pathogenic	0.95
OPA1	O60313-1.3	A744C	Pathogenic	0.982
OPA1	O60313-1.3	A744D	Pathogenic	0.997
OPA1	O60313-1.3	A744E	Pathogenic	0.991
OPA1	O60313-1.3	A744F	Pathogenic	0.995
OPA1	O60313-1.3	A744G	Pathogenic	0.987
OPA1	O60313-1.3	A744H	Pathogenic	0.998
OPA1	O60313-1.3	A744I	Pathogenic	0.985
OPA1	O60313-1.3	A744K	Pathogenic	0.987
OPA1	O60313-1.3	A744L	Pathogenic	0.986
OPA1	O60313-1.3	A744M	Pathogenic	0.991
OPA1	O60313-1.3	A744N	Pathogenic	0.997
OPA1	O60313-1.3	A744P	Pathogenic	0.995
OPA1	O60313-1.3	A744Q	Pathogenic	0.994
OPA1	O60313-1.3	A744R	Pathogenic	0.986
OPA1	O60313-1.3	A744S	Pathogenic	0.964
OPA1	O60313-1.3	A744T	Pathogenic	0.99
OPA1	O60313-1.3	A744V	Pathogenic	0.976
OPA1	O60313-1.3	A744W	Pathogenic	0.997
OPA1	O60313-1.3	A744Y	Pathogenic	0.997
OPA1	O60313-1.3	I745A	Pathogenic	0.817
OPA1	O60313-1.3	I745C	Pathogenic	0.899
OPA1	O60313-1.3	I745D	Pathogenic	0.939
OPA1	O60313-1.3	I745E	Pathogenic	0.949
OPA1	O60313-1.3	I745F	Pathogenic	0.877
OPA1	O60313-1.3	I745G	Pathogenic	0.987
OPA1	O60313-1.3	I745H	Pathogenic	0.975
OPA1	O60313-1.3	I745K	Pathogenic	0.932
OPA1	O60313-1.3	I745L	Neutral	0.449
OPA1	O60313-1.3	I745M	Pathogenic	0.606
OPA1	O60313-1.3	I745N	Pathogenic	0.948
OPA1	O60313-1.3	I745P	Pathogenic	0.984
OPA1	O60313-1.3	I745Q	Pathogenic	0.965
OPA1	O60313-1.3	I745R	Pathogenic	0.928
OPA1	O60313-1.3	I745S	Pathogenic	0.906
OPA1	O60313-1.3	I745T	Pathogenic	0.825
OPA1	O60313-1.3	I745V	Neutral	0.144
OPA1	O60313-1.3	I745W	Pathogenic	0.991
OPA1	O60313-1.3	I745Y	Pathogenic	0.904
OPA1	O60313-1.3	Y746A	Neutral	0.076
OPA1	O60313-1.3	Y746C	Neutral	0.135
OPA1	O60313-1.3	Y746D	Neutral	0.088
OPA1	O60313-1.3	Y746E	Neutral	0.039
OPA1	O60313-1.3	Y746F	Neutral	0.0
OPA1	O60313-1.3	Y746G	Neutral	0.143
OPA1	O60313-1.3	Y746H	Neutral	0.001
OPA1	O60313-1.3	Y746I	Neutral	0.028
OPA1	O60313-1.3	Y746K	Neutral	0.031
OPA1	O60313-1.3	Y746L	Neutral	0.031
OPA1	O60313-1.3	Y746M	Neutral	0.047
OPA1	O60313-1.3	Y746N	Neutral	0.038
OPA1	O60313-1.3	Y746P	Neutral	0.274
OPA1	O60313-1.3	Y746Q	Neutral	0.02
OPA1	O60313-1.3	Y746R	Neutral	0.031
OPA1	O60313-1.3	Y746S	Neutral	0.058
OPA1	O60313-1.3	Y746T	Neutral	0.079
OPA1	O60313-1.3	Y746V	Neutral	0.045
OPA1	O60313-1.3	Y746W	Neutral	0.001
OPA1	O60313-1.3	F747A	Pathogenic	0.996
OPA1	O60313-1.3	F747C	Pathogenic	0.998
OPA1	O60313-1.3	F747D	Pathogenic	0.996
OPA1	O60313-1.3	F747E	Pathogenic	0.997
OPA1	O60313-1.3	F747G	Pathogenic	0.998
OPA1	O60313-1.3	F747H	Pathogenic	0.988
OPA1	O60313-1.3	F747I	Pathogenic	0.992
OPA1	O60313-1.3	F747K	Pathogenic	0.996
OPA1	O60313-1.3	F747L	Pathogenic	0.992
OPA1	O60313-1.3	F747M	Pathogenic	0.987
OPA1	O60313-1.3	F747N	Pathogenic	0.997
OPA1	O60313-1.3	F747P	Pathogenic	1.0
OPA1	O60313-1.3	F747Q	Pathogenic	0.998
OPA1	O60313-1.3	F747R	Pathogenic	0.996
OPA1	O60313-1.3	F747S	Pathogenic	0.994
OPA1	O60313-1.3	F747T	Pathogenic	0.996
OPA1	O60313-1.3	F747V	Pathogenic	0.995
OPA1	O60313-1.3	F747W	Pathogenic	0.965
OPA1	O60313-1.3	F747Y	Pathogenic	0.718
OPA1	O60313-1.3	M748A	Pathogenic	0.914
OPA1	O60313-1.3	M748C	Pathogenic	0.955
OPA1	O60313-1.3	M748D	Pathogenic	0.973
OPA1	O60313-1.3	M748E	Pathogenic	0.938
OPA1	O60313-1.3	M748F	Pathogenic	0.859
OPA1	O60313-1.3	M748G	Pathogenic	0.984
OPA1	O60313-1.3	M748H	Pathogenic	0.969
OPA1	O60313-1.3	M748I	Pathogenic	0.683
OPA1	O60313-1.3	M748K	Pathogenic	0.793
OPA1	O60313-1.3	M748L	Neutral	0.449
OPA1	O60313-1.3	M748N	Pathogenic	0.937
OPA1	O60313-1.3	M748P	Pathogenic	0.98
OPA1	O60313-1.3	M748Q	Pathogenic	0.729
OPA1	O60313-1.3	M748R	Pathogenic	0.783
OPA1	O60313-1.3	M748S	Pathogenic	0.888
OPA1	O60313-1.3	M748T	Pathogenic	0.918
OPA1	O60313-1.3	M748V	Pathogenic	0.77
OPA1	O60313-1.3	M748W	Pathogenic	0.912
OPA1	O60313-1.3	M748Y	Pathogenic	0.957
OPA1	O60313-1.3	E749A	Pathogenic	0.985
OPA1	O60313-1.3	E749C	Pathogenic	0.999
OPA1	O60313-1.3	E749D	Pathogenic	0.858
OPA1	O60313-1.3	E749F	Pathogenic	0.993
OPA1	O60313-1.3	E749G	Pathogenic	0.996
OPA1	O60313-1.3	E749H	Pathogenic	0.967
OPA1	O60313-1.3	E749I	Pathogenic	0.993
OPA1	O60313-1.3	E749K	Pathogenic	0.933
OPA1	O60313-1.3	E749L	Pathogenic	0.994
OPA1	O60313-1.3	E749M	Pathogenic	0.989
OPA1	O60313-1.3	E749N	Pathogenic	0.983
OPA1	O60313-1.3	E749P	Pathogenic	0.979
OPA1	O60313-1.3	E749Q	Pathogenic	0.83
OPA1	O60313-1.3	E749R	Pathogenic	0.974
OPA1	O60313-1.3	E749S	Pathogenic	0.969
OPA1	O60313-1.3	E749T	Pathogenic	0.987
OPA1	O60313-1.3	E749V	Pathogenic	0.989
OPA1	O60313-1.3	E749W	Pathogenic	0.989
OPA1	O60313-1.3	E749Y	Pathogenic	0.991
OPA1	O60313-1.3	E750A	Pathogenic	0.705
OPA1	O60313-1.3	E750C	Pathogenic	0.971
OPA1	O60313-1.3	E750D	Neutral	0.184
OPA1	O60313-1.3	E750F	Pathogenic	0.846
OPA1	O60313-1.3	E750G	Pathogenic	0.895
OPA1	O60313-1.3	E750H	Pathogenic	0.523
OPA1	O60313-1.3	E750I	Pathogenic	0.85
OPA1	O60313-1.3	E750K	Neutral	0.342
OPA1	O60313-1.3	E750L	Pathogenic	0.861
OPA1	O60313-1.3	E750M	Pathogenic	0.767
OPA1	O60313-1.3	E750N	Pathogenic	0.679
OPA1	O60313-1.3	E750P	Pathogenic	0.642
OPA1	O60313-1.3	E750Q	Neutral	0.154
OPA1	O60313-1.3	E750R	Pathogenic	0.586
OPA1	O60313-1.3	E750S	Pathogenic	0.536
OPA1	O60313-1.3	E750T	Pathogenic	0.734
OPA1	O60313-1.3	E750V	Pathogenic	0.777
OPA1	O60313-1.3	E750W	Pathogenic	0.765
OPA1	O60313-1.3	E750Y	Pathogenic	0.798
OPA1	O60313-1.3	A751C	Neutral	0.125
OPA1	O60313-1.3	A751D	Neutral	0.448
OPA1	O60313-1.3	A751E	Neutral	0.228
OPA1	O60313-1.3	A751F	Neutral	0.323
OPA1	O60313-1.3	A751G	Neutral	0.166
OPA1	O60313-1.3	A751H	Pathogenic	0.626
OPA1	O60313-1.3	A751I	Neutral	0.144
OPA1	O60313-1.3	A751K	Neutral	0.163
OPA1	O60313-1.3	A751L	Neutral	0.156
OPA1	O60313-1.3	A751M	Neutral	0.222
OPA1	O60313-1.3	A751N	Neutral	0.482
OPA1	O60313-1.3	A751P	Neutral	0.341
OPA1	O60313-1.3	A751Q	Neutral	0.298
OPA1	O60313-1.3	A751R	Neutral	0.154
OPA1	O60313-1.3	A751S	Neutral	0.065
OPA1	O60313-1.3	A751T	Neutral	0.197
OPA1	O60313-1.3	A751V	Neutral	0.097
OPA1	O60313-1.3	A751W	Neutral	0.449
OPA1	O60313-1.3	A751Y	Neutral	0.498
OPA1	O60313-1.3	L752A	Pathogenic	0.828
OPA1	O60313-1.3	L752C	Pathogenic	0.906
OPA1	O60313-1.3	L752D	Pathogenic	0.98
OPA1	O60313-1.3	L752E	Pathogenic	0.952
OPA1	O60313-1.3	L752F	Pathogenic	0.867
OPA1	O60313-1.3	L752G	Pathogenic	0.988
OPA1	O60313-1.3	L752H	Pathogenic	0.977
OPA1	O60313-1.3	L752I	Neutral	0.444
OPA1	O60313-1.3	L752K	Pathogenic	0.835
OPA1	O60313-1.3	L752M	Neutral	0.363
OPA1	O60313-1.3	L752N	Pathogenic	0.952
OPA1	O60313-1.3	L752P	Pathogenic	0.985
OPA1	O60313-1.3	L752Q	Pathogenic	0.911
OPA1	O60313-1.3	L752R	Pathogenic	0.826
OPA1	O60313-1.3	L752S	Pathogenic	0.912
OPA1	O60313-1.3	L752T	Pathogenic	0.835
OPA1	O60313-1.3	L752V	Pathogenic	0.603
OPA1	O60313-1.3	L752W	Pathogenic	0.97
OPA1	O60313-1.3	L752Y	Pathogenic	0.91
OPA1	O60313-1.3	Q753A	Pathogenic	0.684
OPA1	O60313-1.3	Q753C	Pathogenic	0.913
OPA1	O60313-1.3	Q753D	Neutral	0.445
OPA1	O60313-1.3	Q753E	Neutral	0.103
OPA1	O60313-1.3	Q753F	Pathogenic	0.838
OPA1	O60313-1.3	Q753G	Pathogenic	0.886
OPA1	O60313-1.3	Q753H	Pathogenic	0.508
OPA1	O60313-1.3	Q753I	Pathogenic	0.842
OPA1	O60313-1.3	Q753K	Neutral	0.186
OPA1	O60313-1.3	Q753L	Pathogenic	0.669
OPA1	O60313-1.3	Q753M	Neutral	0.269
OPA1	O60313-1.3	Q753N	Neutral	0.488
OPA1	O60313-1.3	Q753P	Pathogenic	0.619
OPA1	O60313-1.3	Q753R	Neutral	0.176
OPA1	O60313-1.3	Q753S	Pathogenic	0.512
OPA1	O60313-1.3	Q753T	Pathogenic	0.715
OPA1	O60313-1.3	Q753V	Pathogenic	0.759
OPA1	O60313-1.3	Q753W	Pathogenic	0.513
OPA1	O60313-1.3	Q753Y	Pathogenic	0.563
OPA1	O60313-1.3	A754C	Neutral	0.027
OPA1	O60313-1.3	A754D	Neutral	0.137
OPA1	O60313-1.3	A754E	Neutral	0.054
OPA1	O60313-1.3	A754F	Neutral	0.085
OPA1	O60313-1.3	A754G	Neutral	0.037
OPA1	O60313-1.3	A754H	Neutral	0.246
OPA1	O60313-1.3	A754I	Neutral	0.032
OPA1	O60313-1.3	A754K	Neutral	0.037
OPA1	O60313-1.3	A754L	Neutral	0.035
OPA1	O60313-1.3	A754M	Neutral	0.053
OPA1	O60313-1.3	A754N	Neutral	0.154
OPA1	O60313-1.3	A754P	Neutral	0.092
OPA1	O60313-1.3	A754Q	Neutral	0.077
OPA1	O60313-1.3	A754R	Neutral	0.034
OPA1	O60313-1.3	A754S	Neutral	0.013
OPA1	O60313-1.3	A754T	Neutral	0.046
OPA1	O60313-1.3	A754V	Neutral	0.02
OPA1	O60313-1.3	A754W	Neutral	0.137
OPA1	O60313-1.3	A754Y	Neutral	0.162
OPA1	O60313-1.3	R755A	Pathogenic	0.853
OPA1	O60313-1.3	R755C	Pathogenic	0.966
OPA1	O60313-1.3	R755D	Pathogenic	0.98
OPA1	O60313-1.3	R755E	Pathogenic	0.847
OPA1	O60313-1.3	R755F	Pathogenic	0.942
OPA1	O60313-1.3	R755G	Pathogenic	0.954
OPA1	O60313-1.3	R755H	Pathogenic	0.739
OPA1	O60313-1.3	R755I	Pathogenic	0.939
OPA1	O60313-1.3	R755K	Pathogenic	0.501
OPA1	O60313-1.3	R755L	Pathogenic	0.853
OPA1	O60313-1.3	R755M	Pathogenic	0.754
OPA1	O60313-1.3	R755N	Pathogenic	0.836
OPA1	O60313-1.3	R755P	Pathogenic	0.926
OPA1	O60313-1.3	R755Q	Pathogenic	0.571
OPA1	O60313-1.3	R755S	Pathogenic	0.89
OPA1	O60313-1.3	R755T	Pathogenic	0.87
OPA1	O60313-1.3	R755V	Pathogenic	0.961
OPA1	O60313-1.3	R755W	Pathogenic	0.913
OPA1	O60313-1.3	R755Y	Pathogenic	0.924
OPA1	O60313-1.3	L756A	Pathogenic	0.982
OPA1	O60313-1.3	L756C	Pathogenic	0.991
OPA1	O60313-1.3	L756D	Pathogenic	0.998
OPA1	O60313-1.3	L756E	Pathogenic	0.996
OPA1	O60313-1.3	L756F	Pathogenic	0.987
OPA1	O60313-1.3	L756G	Pathogenic	0.999
OPA1	O60313-1.3	L756H	Pathogenic	0.998
OPA1	O60313-1.3	L756I	Pathogenic	0.902
OPA1	O60313-1.3	L756K	Pathogenic	0.983
OPA1	O60313-1.3	L756M	Pathogenic	0.868
OPA1	O60313-1.3	L756N	Pathogenic	0.996
OPA1	O60313-1.3	L756P	Pathogenic	0.999
OPA1	O60313-1.3	L756Q	Pathogenic	0.992
OPA1	O60313-1.3	L756R	Pathogenic	0.982
OPA1	O60313-1.3	L756S	Pathogenic	0.992
OPA1	O60313-1.3	L756T	Pathogenic	0.983
OPA1	O60313-1.3	L756V	Pathogenic	0.946
OPA1	O60313-1.3	L756W	Pathogenic	0.997
OPA1	O60313-1.3	L756Y	Pathogenic	0.992
OPA1	O60313-1.3	K757A	Neutral	0.248
OPA1	O60313-1.3	K757C	Pathogenic	0.616
OPA1	O60313-1.3	K757D	Neutral	0.492
OPA1	O60313-1.3	K757E	Neutral	0.098
OPA1	O60313-1.3	K757F	Neutral	0.479
OPA1	O60313-1.3	K757G	Pathogenic	0.541
OPA1	O60313-1.3	K757H	Neutral	0.319
OPA1	O60313-1.3	K757I	Neutral	0.466
OPA1	O60313-1.3	K757L	Neutral	0.248
OPA1	O60313-1.3	K757M	Neutral	0.149
OPA1	O60313-1.3	K757N	Neutral	0.226
OPA1	O60313-1.3	K757P	Neutral	0.198
OPA1	O60313-1.3	K757Q	Neutral	0.07
OPA1	O60313-1.3	K757R	Neutral	0.051
OPA1	O60313-1.3	K757S	Neutral	0.138
OPA1	O60313-1.3	K757T	Neutral	0.276
OPA1	O60313-1.3	K757V	Neutral	0.324
OPA1	O60313-1.3	K757W	Neutral	0.352
OPA1	O60313-1.3	K757Y	Neutral	0.399
OPA1	O60313-1.3	D758A	Pathogenic	0.837
OPA1	O60313-1.3	D758C	Pathogenic	0.896
OPA1	O60313-1.3	D758E	Neutral	0.15
OPA1	O60313-1.3	D758F	Pathogenic	0.781
OPA1	O60313-1.3	D758G	Pathogenic	0.686
OPA1	O60313-1.3	D758H	Pathogenic	0.673
OPA1	O60313-1.3	D758I	Pathogenic	0.785
OPA1	O60313-1.3	D758K	Pathogenic	0.783
OPA1	O60313-1.3	D758L	Pathogenic	0.921
OPA1	O60313-1.3	D758M	Pathogenic	0.861
OPA1	O60313-1.3	D758N	Neutral	0.342
OPA1	O60313-1.3	D758P	Pathogenic	0.57
OPA1	O60313-1.3	D758Q	Neutral	0.498
OPA1	O60313-1.3	D758R	Pathogenic	0.908
OPA1	O60313-1.3	D758S	Neutral	0.461
OPA1	O60313-1.3	D758T	Pathogenic	0.668
OPA1	O60313-1.3	D758V	Pathogenic	0.87
OPA1	O60313-1.3	D758W	Pathogenic	0.859
OPA1	O60313-1.3	D758Y	Pathogenic	0.881
OPA1	O60313-1.3	T759A	Pathogenic	0.97
OPA1	O60313-1.3	T759C	Pathogenic	0.982
OPA1	O60313-1.3	T759D	Pathogenic	0.977
OPA1	O60313-1.3	T759E	Pathogenic	0.978
OPA1	O60313-1.3	T759F	Pathogenic	0.985
OPA1	O60313-1.3	T759G	Pathogenic	0.995
OPA1	O60313-1.3	T759H	Pathogenic	0.996
OPA1	O60313-1.3	T759I	Pathogenic	0.959
OPA1	O60313-1.3	T759K	Pathogenic	0.967
OPA1	O60313-1.3	T759L	Pathogenic	0.962
OPA1	O60313-1.3	T759M	Pathogenic	0.975
OPA1	O60313-1.3	T759N	Pathogenic	0.943
OPA1	O60313-1.3	T759P	Pathogenic	0.986
OPA1	O60313-1.3	T759Q	Pathogenic	0.985
OPA1	O60313-1.3	T759R	Pathogenic	0.965
OPA1	O60313-1.3	T759S	Pathogenic	0.901
OPA1	O60313-1.3	T759V	Pathogenic	0.936
OPA1	O60313-1.3	T759W	Pathogenic	0.975
OPA1	O60313-1.3	T759Y	Pathogenic	0.993
OPA1	O60313-1.3	E760A	Pathogenic	0.958
OPA1	O60313-1.3	E760C	Pathogenic	0.997
OPA1	O60313-1.3	E760D	Pathogenic	0.684
OPA1	O60313-1.3	E760F	Pathogenic	0.981
OPA1	O60313-1.3	E760G	Pathogenic	0.988
OPA1	O60313-1.3	E760H	Pathogenic	0.913
OPA1	O60313-1.3	E760I	Pathogenic	0.982
OPA1	O60313-1.3	E760K	Pathogenic	0.833
OPA1	O60313-1.3	E760L	Pathogenic	0.983
OPA1	O60313-1.3	E760M	Pathogenic	0.969
OPA1	O60313-1.3	E760N	Pathogenic	0.953
OPA1	O60313-1.3	E760P	Pathogenic	0.945
OPA1	O60313-1.3	E760Q	Pathogenic	0.636
OPA1	O60313-1.3	E760R	Pathogenic	0.931
OPA1	O60313-1.3	E760S	Pathogenic	0.917
OPA1	O60313-1.3	E760T	Pathogenic	0.964
OPA1	O60313-1.3	E760V	Pathogenic	0.971
OPA1	O60313-1.3	E760W	Pathogenic	0.969
OPA1	O60313-1.3	E760Y	Pathogenic	0.974
OPA1	O60313-1.3	N761A	Neutral	0.076
OPA1	O60313-1.3	N761C	Neutral	0.121
OPA1	O60313-1.3	N761D	Neutral	0.007
OPA1	O60313-1.3	N761E	Neutral	0.023
OPA1	O60313-1.3	N761F	Neutral	0.056
OPA1	O60313-1.3	N761G	Neutral	0.012
OPA1	O60313-1.3	N761H	Neutral	0.004
OPA1	O60313-1.3	N761I	Neutral	0.057
OPA1	O60313-1.3	N761K	Neutral	0.015
OPA1	O60313-1.3	N761L	Neutral	0.063
OPA1	O60313-1.3	N761M	Neutral	0.034
OPA1	O60313-1.3	N761P	Neutral	0.058
OPA1	O60313-1.3	N761Q	Neutral	0.016
OPA1	O60313-1.3	N761R	Neutral	0.014
OPA1	O60313-1.3	N761S	Neutral	0.005
OPA1	O60313-1.3	N761T	Neutral	0.011
OPA1	O60313-1.3	N761V	Neutral	0.101
OPA1	O60313-1.3	N761W	Neutral	0.092
OPA1	O60313-1.3	N761Y	Neutral	0.041
OPA1	O60313-1.3	A762C	Neutral	0.031
OPA1	O60313-1.3	A762D	Neutral	0.153
OPA1	O60313-1.3	A762E	Neutral	0.062
OPA1	O60313-1.3	A762F	Neutral	0.096
OPA1	O60313-1.3	A762G	Neutral	0.042
OPA1	O60313-1.3	A762H	Neutral	0.272
OPA1	O60313-1.3	A762I	Neutral	0.036
OPA1	O60313-1.3	A762K	Neutral	0.041
OPA1	O60313-1.3	A762L	Neutral	0.04
OPA1	O60313-1.3	A762M	Neutral	0.06
OPA1	O60313-1.3	A762N	Neutral	0.172
OPA1	O60313-1.3	A762P	Neutral	0.103
OPA1	O60313-1.3	A762Q	Neutral	0.087
OPA1	O60313-1.3	A762R	Neutral	0.039
OPA1	O60313-1.3	A762S	Neutral	0.015
OPA1	O60313-1.3	A762T	Neutral	0.052
OPA1	O60313-1.3	A762V	Neutral	0.023
OPA1	O60313-1.3	A762W	Neutral	0.154
OPA1	O60313-1.3	A762Y	Neutral	0.181
OPA1	O60313-1.3	I763A	Pathogenic	0.68
OPA1	O60313-1.3	I763C	Pathogenic	0.809
OPA1	O60313-1.3	I763D	Pathogenic	0.879
OPA1	O60313-1.3	I763E	Pathogenic	0.898
OPA1	O60313-1.3	I763F	Pathogenic	0.771
OPA1	O60313-1.3	I763G	Pathogenic	0.973
OPA1	O60313-1.3	I763H	Pathogenic	0.948
OPA1	O60313-1.3	I763K	Pathogenic	0.866
OPA1	O60313-1.3	I763L	Neutral	0.278
OPA1	O60313-1.3	I763M	Neutral	0.421
OPA1	O60313-1.3	I763N	Pathogenic	0.896
OPA1	O60313-1.3	I763P	Pathogenic	0.966
OPA1	O60313-1.3	I763Q	Pathogenic	0.929
OPA1	O60313-1.3	I763R	Pathogenic	0.859
OPA1	O60313-1.3	I763S	Pathogenic	0.821
OPA1	O60313-1.3	I763T	Pathogenic	0.691
OPA1	O60313-1.3	I763V	Neutral	0.074
OPA1	O60313-1.3	I763W	Pathogenic	0.98
OPA1	O60313-1.3	I763Y	Pathogenic	0.817
OPA1	O60313-1.3	E764A	Neutral	0.145
OPA1	O60313-1.3	E764C	Pathogenic	0.705
OPA1	O60313-1.3	E764D	Neutral	0.016
OPA1	O60313-1.3	E764F	Neutral	0.28
OPA1	O60313-1.3	E764G	Neutral	0.377
OPA1	O60313-1.3	E764H	Neutral	0.072
OPA1	O60313-1.3	E764I	Neutral	0.286
OPA1	O60313-1.3	E764K	Neutral	0.035
OPA1	O60313-1.3	E764L	Neutral	0.305
OPA1	O60313-1.3	E764M	Neutral	0.189
OPA1	O60313-1.3	E764N	Neutral	0.13
OPA1	O60313-1.3	E764P	Neutral	0.112
OPA1	O60313-1.3	E764Q	Neutral	0.013
OPA1	O60313-1.3	E764R	Neutral	0.091
OPA1	O60313-1.3	E764S	Neutral	0.076
OPA1	O60313-1.3	E764T	Neutral	0.163
OPA1	O60313-1.3	E764V	Neutral	0.197
OPA1	O60313-1.3	E764W	Neutral	0.187
OPA1	O60313-1.3	E764Y	Neutral	0.219
OPA1	O60313-1.3	N765A	Pathogenic	0.749
OPA1	O60313-1.3	N765C	Pathogenic	0.834
OPA1	O60313-1.3	N765D	Neutral	0.209
OPA1	O60313-1.3	N765E	Neutral	0.456
OPA1	O60313-1.3	N765F	Pathogenic	0.683
OPA1	O60313-1.3	N765G	Neutral	0.305
OPA1	O60313-1.3	N765H	Neutral	0.129
OPA1	O60313-1.3	N765I	Pathogenic	0.688
OPA1	O60313-1.3	N765K	Neutral	0.355
OPA1	O60313-1.3	N765L	Pathogenic	0.708
OPA1	O60313-1.3	N765M	Pathogenic	0.563
OPA1	O60313-1.3	N765P	Pathogenic	0.691
OPA1	O60313-1.3	N765Q	Neutral	0.375
OPA1	O60313-1.3	N765R	Neutral	0.341
OPA1	O60313-1.3	N765S	Neutral	0.147
OPA1	O60313-1.3	N765T	Neutral	0.291
OPA1	O60313-1.3	N765V	Pathogenic	0.802
OPA1	O60313-1.3	N765W	Pathogenic	0.786
OPA1	O60313-1.3	N765Y	Pathogenic	0.607
OPA1	O60313-1.3	M766A	Pathogenic	0.994
OPA1	O60313-1.3	M766C	Pathogenic	0.997
OPA1	O60313-1.3	M766D	Pathogenic	0.998
OPA1	O60313-1.3	M766E	Pathogenic	0.996
OPA1	O60313-1.3	M766F	Pathogenic	0.989
OPA1	O60313-1.3	M766G	Pathogenic	0.999
OPA1	O60313-1.3	M766H	Pathogenic	0.998
OPA1	O60313-1.3	M766I	Pathogenic	0.97
OPA1	O60313-1.3	M766K	Pathogenic	0.983
OPA1	O60313-1.3	M766L	Pathogenic	0.925
OPA1	O60313-1.3	M766N	Pathogenic	0.996
OPA1	O60313-1.3	M766P	Pathogenic	0.999
OPA1	O60313-1.3	M766Q	Pathogenic	0.976
OPA1	O60313-1.3	M766R	Pathogenic	0.982
OPA1	O60313-1.3	M766S	Pathogenic	0.992
OPA1	O60313-1.3	M766T	Pathogenic	0.994
OPA1	O60313-1.3	M766V	Pathogenic	0.981
OPA1	O60313-1.3	M766W	Pathogenic	0.994
OPA1	O60313-1.3	M766Y	Pathogenic	0.997
OPA1	O60313-1.3	V767A	Neutral	0.197
OPA1	O60313-1.3	V767C	Pathogenic	0.586
OPA1	O60313-1.3	V767D	Pathogenic	0.709
OPA1	O60313-1.3	V767E	Neutral	0.496
OPA1	O60313-1.3	V767F	Neutral	0.499
OPA1	O60313-1.3	V767G	Pathogenic	0.808
OPA1	O60313-1.3	V767H	Pathogenic	0.848
OPA1	O60313-1.3	V767I	Neutral	0.014
OPA1	O60313-1.3	V767K	Neutral	0.393
OPA1	O60313-1.3	V767L	Neutral	0.118
OPA1	O60313-1.3	V767M	Neutral	0.171
OPA1	O60313-1.3	V767N	Pathogenic	0.743
OPA1	O60313-1.3	V767P	Pathogenic	0.766
OPA1	O60313-1.3	V767Q	Pathogenic	0.586
OPA1	O60313-1.3	V767R	Pathogenic	0.638
OPA1	O60313-1.3	V767S	Pathogenic	0.606
OPA1	O60313-1.3	V767T	Neutral	0.205
OPA1	O60313-1.3	V767W	Pathogenic	0.832
OPA1	O60313-1.3	V767Y	Pathogenic	0.566
OPA1	O60313-1.3	G768A	Pathogenic	0.989
OPA1	O60313-1.3	G768C	Pathogenic	0.999
OPA1	O60313-1.3	G768D	Pathogenic	0.994
OPA1	O60313-1.3	G768E	Pathogenic	0.998
OPA1	O60313-1.3	G768F	Pathogenic	0.998
OPA1	O60313-1.3	G768H	Pathogenic	0.999
OPA1	O60313-1.3	G768I	Pathogenic	0.999
OPA1	O60313-1.3	G768K	Pathogenic	0.997
OPA1	O60313-1.3	G768L	Pathogenic	0.999
OPA1	O60313-1.3	G768M	Pathogenic	0.999
OPA1	O60313-1.3	G768N	Pathogenic	0.984
OPA1	O60313-1.3	G768P	Pathogenic	0.998
OPA1	O60313-1.3	G768Q	Pathogenic	0.999
OPA1	O60313-1.3	G768R	Pathogenic	0.997
OPA1	O60313-1.3	G768S	Pathogenic	0.991
OPA1	O60313-1.3	G768T	Pathogenic	0.999
OPA1	O60313-1.3	G768V	Pathogenic	0.999
OPA1	O60313-1.3	G768W	Pathogenic	0.989
OPA1	O60313-1.3	G768Y	Pathogenic	0.999
OPA1	O60313-1.3	P769A	Pathogenic	0.996
OPA1	O60313-1.3	P769C	Pathogenic	1.0
OPA1	O60313-1.3	P769D	Pathogenic	0.99
OPA1	O60313-1.3	P769E	Pathogenic	0.991
OPA1	O60313-1.3	P769F	Pathogenic	1.0
OPA1	O60313-1.3	P769G	Pathogenic	0.998
OPA1	O60313-1.3	P769H	Pathogenic	0.998
OPA1	O60313-1.3	P769I	Pathogenic	0.999
OPA1	O60313-1.3	P769K	Pathogenic	0.986
OPA1	O60313-1.3	P769L	Pathogenic	0.999
OPA1	O60313-1.3	P769M	Pathogenic	0.998
OPA1	O60313-1.3	P769N	Pathogenic	0.997
OPA1	O60313-1.3	P769Q	Pathogenic	0.994
OPA1	O60313-1.3	P769R	Pathogenic	0.995
OPA1	O60313-1.3	P769S	Pathogenic	0.995
OPA1	O60313-1.3	P769T	Pathogenic	0.996
OPA1	O60313-1.3	P769V	Pathogenic	0.999
OPA1	O60313-1.3	P769W	Pathogenic	0.999
OPA1	O60313-1.3	P769Y	Pathogenic	1.0
OPA1	O60313-1.3	D770A	Pathogenic	0.881
OPA1	O60313-1.3	D770C	Pathogenic	0.926
OPA1	O60313-1.3	D770E	Neutral	0.204
OPA1	O60313-1.3	D770F	Pathogenic	0.837
OPA1	O60313-1.3	D770G	Pathogenic	0.76
OPA1	O60313-1.3	D770H	Pathogenic	0.748
OPA1	O60313-1.3	D770I	Pathogenic	0.841
OPA1	O60313-1.3	D770K	Pathogenic	0.839
OPA1	O60313-1.3	D770L	Pathogenic	0.944
OPA1	O60313-1.3	D770M	Pathogenic	0.899
OPA1	O60313-1.3	D770N	Neutral	0.429
OPA1	O60313-1.3	D770P	Pathogenic	0.657
OPA1	O60313-1.3	D770Q	Pathogenic	0.59
OPA1	O60313-1.3	D770R	Pathogenic	0.934
OPA1	O60313-1.3	D770S	Pathogenic	0.553
OPA1	O60313-1.3	D770T	Pathogenic	0.745
OPA1	O60313-1.3	D770V	Pathogenic	0.907
OPA1	O60313-1.3	D770W	Pathogenic	0.898
OPA1	O60313-1.3	D770Y	Pathogenic	0.915
OPA1	O60313-1.3	W771A	Pathogenic	0.93
OPA1	O60313-1.3	W771C	Pathogenic	0.901
OPA1	O60313-1.3	W771D	Pathogenic	0.94
OPA1	O60313-1.3	W771E	Pathogenic	0.867
OPA1	O60313-1.3	W771F	Neutral	0.484
OPA1	O60313-1.3	W771G	Pathogenic	0.763
OPA1	O60313-1.3	W771H	Pathogenic	0.825
OPA1	O60313-1.3	W771I	Pathogenic	0.985
OPA1	O60313-1.3	W771K	Pathogenic	0.839
OPA1	O60313-1.3	W771L	Pathogenic	0.953
OPA1	O60313-1.3	W771M	Pathogenic	0.82
OPA1	O60313-1.3	W771N	Pathogenic	0.949
OPA1	O60313-1.3	W771P	Pathogenic	0.984
OPA1	O60313-1.3	W771Q	Pathogenic	0.771
OPA1	O60313-1.3	W771R	Pathogenic	0.844
OPA1	O60313-1.3	W771S	Pathogenic	0.908
OPA1	O60313-1.3	W771T	Pathogenic	0.828
OPA1	O60313-1.3	W771V	Pathogenic	0.972
OPA1	O60313-1.3	W771Y	Neutral	0.134
OPA1	O60313-1.3	K772A	Pathogenic	0.846
OPA1	O60313-1.3	K772C	Pathogenic	0.964
OPA1	O60313-1.3	K772D	Pathogenic	0.942
OPA1	O60313-1.3	K772E	Pathogenic	0.645
OPA1	O60313-1.3	K772F	Pathogenic	0.939
OPA1	O60313-1.3	K772G	Pathogenic	0.952
OPA1	O60313-1.3	K772H	Pathogenic	0.886
OPA1	O60313-1.3	K772I	Pathogenic	0.936
OPA1	O60313-1.3	K772L	Pathogenic	0.846
OPA1	O60313-1.3	K772M	Pathogenic	0.745
OPA1	O60313-1.3	K772N	Pathogenic	0.829
OPA1	O60313-1.3	K772P	Pathogenic	0.804
OPA1	O60313-1.3	K772Q	Pathogenic	0.558
OPA1	O60313-1.3	K772R	Neutral	0.473
OPA1	O60313-1.3	K772S	Pathogenic	0.727
OPA1	O60313-1.3	K772T	Pathogenic	0.864
OPA1	O60313-1.3	K772V	Pathogenic	0.889
OPA1	O60313-1.3	K772W	Pathogenic	0.901
OPA1	O60313-1.3	K772Y	Pathogenic	0.917
OPA1	O60313-1.3	K773A	Neutral	0.184
OPA1	O60313-1.3	K773C	Pathogenic	0.523
OPA1	O60313-1.3	K773D	Neutral	0.397
OPA1	O60313-1.3	K773E	Neutral	0.069
OPA1	O60313-1.3	K773F	Neutral	0.386
OPA1	O60313-1.3	K773G	Neutral	0.446
OPA1	O60313-1.3	K773H	Neutral	0.242
OPA1	O60313-1.3	K773I	Neutral	0.373
OPA1	O60313-1.3	K773L	Neutral	0.184
OPA1	O60313-1.3	K773M	Neutral	0.107
OPA1	O60313-1.3	K773N	Neutral	0.166
OPA1	O60313-1.3	K773P	Neutral	0.144
OPA1	O60313-1.3	K773Q	Neutral	0.049
OPA1	O60313-1.3	K773R	Neutral	0.035
OPA1	O60313-1.3	K773S	Neutral	0.098
OPA1	O60313-1.3	K773T	Neutral	0.206
OPA1	O60313-1.3	K773V	Neutral	0.246
OPA1	O60313-1.3	K773W	Neutral	0.27
OPA1	O60313-1.3	K773Y	Neutral	0.311
OPA1	O60313-1.3	R774A	Pathogenic	0.969
OPA1	O60313-1.3	R774C	Pathogenic	0.994
OPA1	O60313-1.3	R774D	Pathogenic	0.996
OPA1	O60313-1.3	R774E	Pathogenic	0.968
OPA1	O60313-1.3	R774F	Pathogenic	0.989
OPA1	O60313-1.3	R774G	Pathogenic	0.991
OPA1	O60313-1.3	R774H	Pathogenic	0.94
OPA1	O60313-1.3	R774I	Pathogenic	0.988
OPA1	O60313-1.3	R774K	Pathogenic	0.846
OPA1	O60313-1.3	R774L	Pathogenic	0.969
OPA1	O60313-1.3	R774M	Pathogenic	0.944
OPA1	O60313-1.3	R774N	Pathogenic	0.966
OPA1	O60313-1.3	R774P	Pathogenic	0.986
OPA1	O60313-1.3	R774Q	Pathogenic	0.879
OPA1	O60313-1.3	R774S	Pathogenic	0.978
OPA1	O60313-1.3	R774T	Pathogenic	0.973
OPA1	O60313-1.3	R774V	Pathogenic	0.993
OPA1	O60313-1.3	R774W	Pathogenic	0.983
OPA1	O60313-1.3	R774Y	Pathogenic	0.985
OPA1	O60313-1.3	W775A	Pathogenic	0.995
OPA1	O60313-1.3	W775C	Pathogenic	0.993
OPA1	O60313-1.3	W775D	Pathogenic	0.996
OPA1	O60313-1.3	W775E	Pathogenic	0.99
OPA1	O60313-1.3	W775F	Pathogenic	0.934
OPA1	O60313-1.3	W775G	Pathogenic	0.98
OPA1	O60313-1.3	W775H	Pathogenic	0.986
OPA1	O60313-1.3	W775I	Pathogenic	0.999
OPA1	O60313-1.3	W775K	Pathogenic	0.987
OPA1	O60313-1.3	W775L	Pathogenic	0.997
OPA1	O60313-1.3	W775M	Pathogenic	0.986
OPA1	O60313-1.3	W775N	Pathogenic	0.996
OPA1	O60313-1.3	W775P	Pathogenic	0.999
OPA1	O60313-1.3	W775Q	Pathogenic	0.981
OPA1	O60313-1.3	W775R	Pathogenic	0.988
OPA1	O60313-1.3	W775S	Pathogenic	0.993
OPA1	O60313-1.3	W775T	Pathogenic	0.986
OPA1	O60313-1.3	W775V	Pathogenic	0.998
OPA1	O60313-1.3	W775Y	Pathogenic	0.701
OPA1	O60313-1.3	L776A	Neutral	0.289
OPA1	O60313-1.3	L776C	Neutral	0.448
OPA1	O60313-1.3	L776D	Pathogenic	0.802
OPA1	O60313-1.3	L776E	Pathogenic	0.628
OPA1	O60313-1.3	L776F	Neutral	0.355
OPA1	O60313-1.3	L776G	Pathogenic	0.875
OPA1	O60313-1.3	L776H	Pathogenic	0.779
OPA1	O60313-1.3	L776I	Neutral	0.063
OPA1	O60313-1.3	L776K	Neutral	0.299
OPA1	O60313-1.3	L776M	Neutral	0.046
OPA1	O60313-1.3	L776N	Pathogenic	0.624
OPA1	O60313-1.3	L776P	Pathogenic	0.844
OPA1	O60313-1.3	L776Q	Neutral	0.465
OPA1	O60313-1.3	L776R	Neutral	0.287
OPA1	O60313-1.3	L776S	Neutral	0.468
OPA1	O60313-1.3	L776T	Neutral	0.3
OPA1	O60313-1.3	L776V	Neutral	0.114
OPA1	O60313-1.3	L776W	Pathogenic	0.732
OPA1	O60313-1.3	L776Y	Neutral	0.462
OPA1	O60313-1.3	Y777A	Pathogenic	0.734
OPA1	O60313-1.3	Y777C	Pathogenic	0.841
OPA1	O60313-1.3	Y777D	Pathogenic	0.766
OPA1	O60313-1.3	Y777E	Pathogenic	0.576
OPA1	O60313-1.3	Y777F	Neutral	0.015
OPA1	O60313-1.3	Y777G	Pathogenic	0.849
OPA1	O60313-1.3	Y777H	Neutral	0.039
OPA1	O60313-1.3	Y777I	Neutral	0.498
OPA1	O60313-1.3	Y777K	Pathogenic	0.521
OPA1	O60313-1.3	Y777L	Pathogenic	0.521
OPA1	O60313-1.3	Y777M	Pathogenic	0.626
OPA1	O60313-1.3	Y777N	Pathogenic	0.573
OPA1	O60313-1.3	Y777P	Pathogenic	0.927
OPA1	O60313-1.3	Y777Q	Neutral	0.412
OPA1	O60313-1.3	Y777R	Pathogenic	0.516
OPA1	O60313-1.3	Y777S	Pathogenic	0.673
OPA1	O60313-1.3	Y777T	Pathogenic	0.744
OPA1	O60313-1.3	Y777V	Pathogenic	0.612
OPA1	O60313-1.3	Y777W	Neutral	0.026
OPA1	O60313-1.3	W778A	Pathogenic	0.998
OPA1	O60313-1.3	W778C	Pathogenic	0.997
OPA1	O60313-1.3	W778D	Pathogenic	0.998
OPA1	O60313-1.3	W778E	Pathogenic	0.996
OPA1	O60313-1.3	W778F	Pathogenic	0.973
OPA1	O60313-1.3	W778G	Pathogenic	0.992
OPA1	O60313-1.3	W778H	Pathogenic	0.994
OPA1	O60313-1.3	W778I	Pathogenic	1.0
OPA1	O60313-1.3	W778K	Pathogenic	0.995
OPA1	O60313-1.3	W778L	Pathogenic	0.999
OPA1	O60313-1.3	W778M	Pathogenic	0.994
OPA1	O60313-1.3	W778N	Pathogenic	0.999
OPA1	O60313-1.3	W778P	Pathogenic	1.0
OPA1	O60313-1.3	W778Q	Pathogenic	0.992
OPA1	O60313-1.3	W778R	Pathogenic	0.995
OPA1	O60313-1.3	W778S	Pathogenic	0.997
OPA1	O60313-1.3	W778T	Pathogenic	0.995
OPA1	O60313-1.3	W778V	Pathogenic	0.999
OPA1	O60313-1.3	W778Y	Pathogenic	0.855
OPA1	O60313-1.3	K779A	Neutral	0.018
OPA1	O60313-1.3	K779C	Neutral	0.083
OPA1	O60313-1.3	K779D	Neutral	0.052
OPA1	O60313-1.3	K779E	Neutral	0.006
OPA1	O60313-1.3	K779F	Neutral	0.05
OPA1	O60313-1.3	K779G	Neutral	0.063
OPA1	O60313-1.3	K779H	Neutral	0.026
OPA1	O60313-1.3	K779I	Neutral	0.047
OPA1	O60313-1.3	K779L	Neutral	0.018
OPA1	O60313-1.3	K779M	Neutral	0.01
OPA1	O60313-1.3	K779N	Neutral	0.016
OPA1	O60313-1.3	K779P	Neutral	0.014
OPA1	O60313-1.3	K779Q	Neutral	0.004
OPA1	O60313-1.3	K779R	Neutral	0.003
OPA1	O60313-1.3	K779S	Neutral	0.009
OPA1	O60313-1.3	K779T	Neutral	0.021
OPA1	O60313-1.3	K779V	Neutral	0.026
OPA1	O60313-1.3	K779W	Neutral	0.03
OPA1	O60313-1.3	K779Y	Neutral	0.036
OPA1	O60313-1.3	N780A	Pathogenic	0.657
OPA1	O60313-1.3	N780C	Pathogenic	0.762
OPA1	O60313-1.3	N780D	Neutral	0.145
OPA1	O60313-1.3	N780E	Neutral	0.349
OPA1	O60313-1.3	N780F	Pathogenic	0.579
OPA1	O60313-1.3	N780G	Neutral	0.219
OPA1	O60313-1.3	N780H	Neutral	0.086
OPA1	O60313-1.3	N780I	Pathogenic	0.586
OPA1	O60313-1.3	N780K	Neutral	0.261
OPA1	O60313-1.3	N780L	Pathogenic	0.608
OPA1	O60313-1.3	N780M	Neutral	0.452
OPA1	O60313-1.3	N780P	Pathogenic	0.589
OPA1	O60313-1.3	N780Q	Neutral	0.277
OPA1	O60313-1.3	N780R	Neutral	0.249
OPA1	O60313-1.3	N780S	Neutral	0.099
OPA1	O60313-1.3	N780T	Neutral	0.208
OPA1	O60313-1.3	N780V	Pathogenic	0.722
OPA1	O60313-1.3	N780W	Pathogenic	0.702
OPA1	O60313-1.3	N780Y	Neutral	0.498
OPA1	O60313-1.3	R781A	Pathogenic	0.534
OPA1	O60313-1.3	R781C	Pathogenic	0.848
OPA1	O60313-1.3	R781D	Pathogenic	0.907
OPA1	O60313-1.3	R781E	Pathogenic	0.524
OPA1	O60313-1.3	R781F	Pathogenic	0.762
OPA1	O60313-1.3	R781G	Pathogenic	0.804
OPA1	O60313-1.3	R781H	Neutral	0.36
OPA1	O60313-1.3	R781I	Pathogenic	0.752
OPA1	O60313-1.3	R781K	Neutral	0.166
OPA1	O60313-1.3	R781L	Pathogenic	0.535
OPA1	O60313-1.3	R781M	Neutral	0.379
OPA1	O60313-1.3	R781N	Pathogenic	0.504
OPA1	O60313-1.3	R781P	Pathogenic	0.714
OPA1	O60313-1.3	R781Q	Neutral	0.209
OPA1	O60313-1.3	R781S	Pathogenic	0.617
OPA1	O60313-1.3	R781T	Pathogenic	0.57
OPA1	O60313-1.3	R781V	Pathogenic	0.829
OPA1	O60313-1.3	R781W	Pathogenic	0.676
OPA1	O60313-1.3	R781Y	Pathogenic	0.707
OPA1	O60313-1.3	T782A	Pathogenic	0.872
OPA1	O60313-1.3	T782C	Pathogenic	0.92
OPA1	O60313-1.3	T782D	Pathogenic	0.898
OPA1	O60313-1.3	T782E	Pathogenic	0.905
OPA1	O60313-1.3	T782F	Pathogenic	0.933
OPA1	O60313-1.3	T782G	Pathogenic	0.978
OPA1	O60313-1.3	T782H	Pathogenic	0.982
OPA1	O60313-1.3	T782I	Pathogenic	0.831
OPA1	O60313-1.3	T782K	Pathogenic	0.862
OPA1	O60313-1.3	T782L	Pathogenic	0.844
OPA1	O60313-1.3	T782M	Pathogenic	0.893
OPA1	O60313-1.3	T782N	Pathogenic	0.78
OPA1	O60313-1.3	T782P	Pathogenic	0.937
OPA1	O60313-1.3	T782Q	Pathogenic	0.932
OPA1	O60313-1.3	T782R	Pathogenic	0.854
OPA1	O60313-1.3	T782S	Pathogenic	0.658
OPA1	O60313-1.3	T782V	Pathogenic	0.758
OPA1	O60313-1.3	T782W	Pathogenic	0.891
OPA1	O60313-1.3	T782Y	Pathogenic	0.967
OPA1	O60313-1.3	Q783A	Neutral	0.051
OPA1	O60313-1.3	Q783C	Neutral	0.207
OPA1	O60313-1.3	Q783D	Neutral	0.019
OPA1	O60313-1.3	Q783E	Neutral	0.003
OPA1	O60313-1.3	Q783F	Neutral	0.114
OPA1	O60313-1.3	Q783G	Neutral	0.161
OPA1	O60313-1.3	Q783H	Neutral	0.025
OPA1	O60313-1.3	Q783I	Neutral	0.116
OPA1	O60313-1.3	Q783K	Neutral	0.006
OPA1	O60313-1.3	Q783L	Neutral	0.048
OPA1	O60313-1.3	Q783M	Neutral	0.009
OPA1	O60313-1.3	Q783N	Neutral	0.023
OPA1	O60313-1.3	Q783P	Neutral	0.039
OPA1	O60313-1.3	Q783R	Neutral	0.005
OPA1	O60313-1.3	Q783S	Neutral	0.025
OPA1	O60313-1.3	Q783T	Neutral	0.058
OPA1	O60313-1.3	Q783V	Neutral	0.072
OPA1	O60313-1.3	Q783W	Neutral	0.025
OPA1	O60313-1.3	Q783Y	Neutral	0.031
OPA1	O60313-1.3	E784A	Pathogenic	0.919
OPA1	O60313-1.3	E784C	Pathogenic	0.994
OPA1	O60313-1.3	E784D	Pathogenic	0.517
OPA1	O60313-1.3	E784F	Pathogenic	0.963
OPA1	O60313-1.3	E784G	Pathogenic	0.976
OPA1	O60313-1.3	E784H	Pathogenic	0.839
OPA1	O60313-1.3	E784I	Pathogenic	0.964
OPA1	O60313-1.3	E784K	Pathogenic	0.711
OPA1	O60313-1.3	E784L	Pathogenic	0.967
OPA1	O60313-1.3	E784M	Pathogenic	0.94
OPA1	O60313-1.3	E784N	Pathogenic	0.909
OPA1	O60313-1.3	E784P	Pathogenic	0.895
OPA1	O60313-1.3	E784Q	Neutral	0.464
OPA1	O60313-1.3	E784R	Pathogenic	0.87
OPA1	O60313-1.3	E784S	Pathogenic	0.846
OPA1	O60313-1.3	E784T	Pathogenic	0.929
OPA1	O60313-1.3	E784V	Pathogenic	0.943
OPA1	O60313-1.3	E784W	Pathogenic	0.939
OPA1	O60313-1.3	E784Y	Pathogenic	0.949
OPA1	O60313-1.3	Q785A	Pathogenic	0.993
OPA1	O60313-1.3	Q785C	Pathogenic	0.998
OPA1	O60313-1.3	Q785D	Pathogenic	0.98
OPA1	O60313-1.3	Q785E	Pathogenic	0.876
OPA1	O60313-1.3	Q785F	Pathogenic	0.997
OPA1	O60313-1.3	Q785G	Pathogenic	0.998
OPA1	O60313-1.3	Q785H	Pathogenic	0.984
OPA1	O60313-1.3	Q785I	Pathogenic	0.997
OPA1	O60313-1.3	Q785K	Pathogenic	0.933
OPA1	O60313-1.3	Q785L	Pathogenic	0.992
OPA1	O60313-1.3	Q785M	Pathogenic	0.958
OPA1	O60313-1.3	Q785N	Pathogenic	0.983
OPA1	O60313-1.3	Q785P	Pathogenic	0.99
OPA1	O60313-1.3	Q785R	Pathogenic	0.929
OPA1	O60313-1.3	Q785S	Pathogenic	0.985
OPA1	O60313-1.3	Q785T	Pathogenic	0.994
OPA1	O60313-1.3	Q785V	Pathogenic	0.995
OPA1	O60313-1.3	Q785W	Pathogenic	0.985
OPA1	O60313-1.3	Q785Y	Pathogenic	0.987
OPA1	O60313-1.3	C786A	Neutral	0.004
OPA1	O60313-1.3	C786D	Neutral	0.034
OPA1	O60313-1.3	C786E	Neutral	0.097
OPA1	O60313-1.3	C786F	Neutral	0.024
OPA1	O60313-1.3	C786G	Neutral	0.059
OPA1	O60313-1.3	C786H	Neutral	0.068
OPA1	O60313-1.3	C786I	Neutral	0.009
OPA1	O60313-1.3	C786K	Neutral	0.024
OPA1	O60313-1.3	C786L	Neutral	0.009
OPA1	O60313-1.3	C786M	Neutral	0.014
OPA1	O60313-1.3	C786N	Neutral	0.039
OPA1	O60313-1.3	C786P	Neutral	0.121
OPA1	O60313-1.3	C786Q	Neutral	0.051
OPA1	O60313-1.3	C786R	Neutral	0.022
OPA1	O60313-1.3	C786S	Neutral	0.008
OPA1	O60313-1.3	C786T	Neutral	0.011
OPA1	O60313-1.3	C786V	Neutral	0.016
OPA1	O60313-1.3	C786W	Neutral	0.014
OPA1	O60313-1.3	C786Y	Neutral	0.047
OPA1	O60313-1.3	V787A	Neutral	0.046
OPA1	O60313-1.3	V787C	Neutral	0.216
OPA1	O60313-1.3	V787D	Neutral	0.322
OPA1	O60313-1.3	V787E	Neutral	0.161
OPA1	O60313-1.3	V787F	Neutral	0.163
OPA1	O60313-1.3	V787G	Neutral	0.45
OPA1	O60313-1.3	V787H	Pathogenic	0.522
OPA1	O60313-1.3	V787I	Neutral	0.003
OPA1	O60313-1.3	V787K	Neutral	0.112
OPA1	O60313-1.3	V787L	Neutral	0.025
OPA1	O60313-1.3	V787M	Neutral	0.039
OPA1	O60313-1.3	V787N	Neutral	0.361
OPA1	O60313-1.3	V787P	Neutral	0.39
OPA1	O60313-1.3	V787Q	Neutral	0.217
OPA1	O60313-1.3	V787R	Neutral	0.256
OPA1	O60313-1.3	V787S	Neutral	0.231
OPA1	O60313-1.3	V787T	Neutral	0.048
OPA1	O60313-1.3	V787W	Neutral	0.491
OPA1	O60313-1.3	V787Y	Neutral	0.203
OPA1	O60313-1.3	H788A	Pathogenic	0.905
OPA1	O60313-1.3	H788C	Pathogenic	0.941
OPA1	O60313-1.3	H788D	Pathogenic	0.649
OPA1	O60313-1.3	H788E	Neutral	0.435
OPA1	O60313-1.3	H788F	Neutral	0.49
OPA1	O60313-1.3	H788G	Pathogenic	0.902
OPA1	O60313-1.3	H788I	Pathogenic	0.893
OPA1	O60313-1.3	H788K	Pathogenic	0.611
OPA1	O60313-1.3	H788L	Pathogenic	0.901
OPA1	O60313-1.3	H788M	Pathogenic	0.829
OPA1	O60313-1.3	H788N	Neutral	0.207
OPA1	O60313-1.3	H788P	Pathogenic	0.877
OPA1	O60313-1.3	H788Q	Pathogenic	0.535
OPA1	O60313-1.3	H788R	Neutral	0.337
OPA1	O60313-1.3	H788S	Pathogenic	0.772
OPA1	O60313-1.3	H788T	Pathogenic	0.917
OPA1	O60313-1.3	H788V	Pathogenic	0.933
OPA1	O60313-1.3	H788W	Pathogenic	0.622
OPA1	O60313-1.3	H788Y	Neutral	0.076
OPA1	O60313-1.3	N789A	Pathogenic	0.852
OPA1	O60313-1.3	N789C	Pathogenic	0.906
OPA1	O60313-1.3	N789D	Neutral	0.338
OPA1	O60313-1.3	N789E	Pathogenic	0.618
OPA1	O60313-1.3	N789F	Pathogenic	0.806
OPA1	O60313-1.3	N789G	Neutral	0.459
OPA1	O60313-1.3	N789H	Neutral	0.222
OPA1	O60313-1.3	N789I	Pathogenic	0.81
OPA1	O60313-1.3	N789K	Pathogenic	0.516
OPA1	O60313-1.3	N789L	Pathogenic	0.824
OPA1	O60313-1.3	N789M	Pathogenic	0.713
OPA1	O60313-1.3	N789P	Pathogenic	0.812
OPA1	O60313-1.3	N789Q	Pathogenic	0.537
OPA1	O60313-1.3	N789R	Pathogenic	0.5
OPA1	O60313-1.3	N789S	Neutral	0.249
OPA1	O60313-1.3	N789T	Neutral	0.442
OPA1	O60313-1.3	N789V	Pathogenic	0.887
OPA1	O60313-1.3	N789W	Pathogenic	0.877
OPA1	O60313-1.3	N789Y	Pathogenic	0.75
OPA1	O60313-1.3	E790A	Pathogenic	0.642
OPA1	O60313-1.3	E790C	Pathogenic	0.962
OPA1	O60313-1.3	E790D	Neutral	0.145
OPA1	O60313-1.3	E790F	Pathogenic	0.805
OPA1	O60313-1.3	E790G	Pathogenic	0.865
OPA1	O60313-1.3	E790H	Neutral	0.452
OPA1	O60313-1.3	E790I	Pathogenic	0.809
OPA1	O60313-1.3	E790K	Neutral	0.281
OPA1	O60313-1.3	E790L	Pathogenic	0.824
OPA1	O60313-1.3	E790M	Pathogenic	0.712
OPA1	O60313-1.3	E790N	Pathogenic	0.613
OPA1	O60313-1.3	E790P	Pathogenic	0.573
OPA1	O60313-1.3	E790Q	Neutral	0.121
OPA1	O60313-1.3	E790R	Pathogenic	0.516
OPA1	O60313-1.3	E790S	Neutral	0.465
OPA1	O60313-1.3	E790T	Pathogenic	0.675
OPA1	O60313-1.3	E790V	Pathogenic	0.723
OPA1	O60313-1.3	E790W	Pathogenic	0.709
OPA1	O60313-1.3	E790Y	Pathogenic	0.748
OPA1	O60313-1.3	T791A	Pathogenic	0.866
OPA1	O60313-1.3	T791C	Pathogenic	0.916
OPA1	O60313-1.3	T791D	Pathogenic	0.894
OPA1	O60313-1.3	T791E	Pathogenic	0.9
OPA1	O60313-1.3	T791F	Pathogenic	0.93
OPA1	O60313-1.3	T791G	Pathogenic	0.977
OPA1	O60313-1.3	T791H	Pathogenic	0.981
OPA1	O60313-1.3	T791I	Pathogenic	0.824
OPA1	O60313-1.3	T791K	Pathogenic	0.856
OPA1	O60313-1.3	T791L	Pathogenic	0.837
OPA1	O60313-1.3	T791M	Pathogenic	0.888
OPA1	O60313-1.3	T791N	Pathogenic	0.771
OPA1	O60313-1.3	T791P	Pathogenic	0.934
OPA1	O60313-1.3	T791Q	Pathogenic	0.928
OPA1	O60313-1.3	T791R	Pathogenic	0.848
OPA1	O60313-1.3	T791S	Pathogenic	0.647
OPA1	O60313-1.3	T791V	Pathogenic	0.748
OPA1	O60313-1.3	T791W	Pathogenic	0.886
OPA1	O60313-1.3	T791Y	Pathogenic	0.965
OPA1	O60313-1.3	K792A	Pathogenic	0.962
OPA1	O60313-1.3	K792C	Pathogenic	0.992
OPA1	O60313-1.3	K792D	Pathogenic	0.987
OPA1	O60313-1.3	K792E	Pathogenic	0.892
OPA1	O60313-1.3	K792F	Pathogenic	0.986
OPA1	O60313-1.3	K792G	Pathogenic	0.989
OPA1	O60313-1.3	K792H	Pathogenic	0.973
OPA1	O60313-1.3	K792I	Pathogenic	0.985
OPA1	O60313-1.3	K792L	Pathogenic	0.962
OPA1	O60313-1.3	K792M	Pathogenic	0.93
OPA1	O60313-1.3	K792N	Pathogenic	0.957
OPA1	O60313-1.3	K792P	Pathogenic	0.949
OPA1	O60313-1.3	K792Q	Pathogenic	0.852
OPA1	O60313-1.3	K792R	Pathogenic	0.803
OPA1	O60313-1.3	K792S	Pathogenic	0.924
OPA1	O60313-1.3	K792T	Pathogenic	0.967
OPA1	O60313-1.3	K792V	Pathogenic	0.973
OPA1	O60313-1.3	K792W	Pathogenic	0.976
OPA1	O60313-1.3	K792Y	Pathogenic	0.981
OPA1	O60313-1.3	N793A	Pathogenic	0.944
OPA1	O60313-1.3	N793C	Pathogenic	0.966
OPA1	O60313-1.3	N793D	Pathogenic	0.596
OPA1	O60313-1.3	N793E	Pathogenic	0.824
OPA1	O60313-1.3	N793F	Pathogenic	0.923
OPA1	O60313-1.3	N793G	Pathogenic	0.71
OPA1	O60313-1.3	N793H	Neutral	0.453
OPA1	O60313-1.3	N793I	Pathogenic	0.925
OPA1	O60313-1.3	N793K	Pathogenic	0.755
OPA1	O60313-1.3	N793L	Pathogenic	0.931
OPA1	O60313-1.3	N793M	Pathogenic	0.878
OPA1	O60313-1.3	N793P	Pathogenic	0.926
OPA1	O60313-1.3	N793Q	Pathogenic	0.77
OPA1	O60313-1.3	N793R	Pathogenic	0.743
OPA1	O60313-1.3	N793S	Neutral	0.49
OPA1	O60313-1.3	N793T	Pathogenic	0.697
OPA1	O60313-1.3	N793V	Pathogenic	0.958
OPA1	O60313-1.3	N793W	Pathogenic	0.954
OPA1	O60313-1.3	N793Y	Pathogenic	0.896
OPA1	O60313-1.3	E794A	Pathogenic	0.983
OPA1	O60313-1.3	E794C	Pathogenic	0.999
OPA1	O60313-1.3	E794D	Pathogenic	0.848
OPA1	O60313-1.3	E794F	Pathogenic	0.993
OPA1	O60313-1.3	E794G	Pathogenic	0.995
OPA1	O60313-1.3	E794H	Pathogenic	0.964
OPA1	O60313-1.3	E794I	Pathogenic	0.993
OPA1	O60313-1.3	E794K	Pathogenic	0.928
OPA1	O60313-1.3	E794L	Pathogenic	0.994
OPA1	O60313-1.3	E794M	Pathogenic	0.988
OPA1	O60313-1.3	E794N	Pathogenic	0.981
OPA1	O60313-1.3	E794P	Pathogenic	0.978
OPA1	O60313-1.3	E794Q	Pathogenic	0.819
OPA1	O60313-1.3	E794R	Pathogenic	0.972
OPA1	O60313-1.3	E794S	Pathogenic	0.966
OPA1	O60313-1.3	E794T	Pathogenic	0.986
OPA1	O60313-1.3	E794V	Pathogenic	0.988
OPA1	O60313-1.3	E794W	Pathogenic	0.988
OPA1	O60313-1.3	E794Y	Pathogenic	0.99
OPA1	O60313-1.3	L795A	Pathogenic	0.982
OPA1	O60313-1.3	L795C	Pathogenic	0.991
OPA1	O60313-1.3	L795D	Pathogenic	0.998
OPA1	O60313-1.3	L795E	Pathogenic	0.996
OPA1	O60313-1.3	L795F	Pathogenic	0.987
OPA1	O60313-1.3	L795G	Pathogenic	0.999
OPA1	O60313-1.3	L795H	Pathogenic	0.998
OPA1	O60313-1.3	L795I	Pathogenic	0.902
OPA1	O60313-1.3	L795K	Pathogenic	0.983
OPA1	O60313-1.3	L795M	Pathogenic	0.868
OPA1	O60313-1.3	L795N	Pathogenic	0.996
OPA1	O60313-1.3	L795P	Pathogenic	0.999
OPA1	O60313-1.3	L795Q	Pathogenic	0.992
OPA1	O60313-1.3	L795R	Pathogenic	0.982
OPA1	O60313-1.3	L795S	Pathogenic	0.992
OPA1	O60313-1.3	L795T	Pathogenic	0.983
OPA1	O60313-1.3	L795V	Pathogenic	0.946
OPA1	O60313-1.3	L795W	Pathogenic	0.997
OPA1	O60313-1.3	L795Y	Pathogenic	0.992
OPA1	O60313-1.3	E796A	Pathogenic	0.781
OPA1	O60313-1.3	E796C	Pathogenic	0.981
OPA1	O60313-1.3	E796D	Neutral	0.252
OPA1	O60313-1.3	E796F	Pathogenic	0.891
OPA1	O60313-1.3	E796G	Pathogenic	0.927
OPA1	O60313-1.3	E796H	Pathogenic	0.621
OPA1	O60313-1.3	E796I	Pathogenic	0.894
OPA1	O60313-1.3	E796K	Neutral	0.437
OPA1	O60313-1.3	E796L	Pathogenic	0.903
OPA1	O60313-1.3	E796M	Pathogenic	0.831
OPA1	O60313-1.3	E796N	Pathogenic	0.759
OPA1	O60313-1.3	E796P	Pathogenic	0.728
OPA1	O60313-1.3	E796Q	Neutral	0.214
OPA1	O60313-1.3	E796R	Pathogenic	0.679
OPA1	O60313-1.3	E796S	Pathogenic	0.633
OPA1	O60313-1.3	E796T	Pathogenic	0.805
OPA1	O60313-1.3	E796V	Pathogenic	0.838
OPA1	O60313-1.3	E796W	Pathogenic	0.829
OPA1	O60313-1.3	E796Y	Pathogenic	0.855
OPA1	O60313-1.3	K797A	Pathogenic	0.76
OPA1	O60313-1.3	K797C	Pathogenic	0.939
OPA1	O60313-1.3	K797D	Pathogenic	0.903
OPA1	O60313-1.3	K797E	Pathogenic	0.511
OPA1	O60313-1.3	K797F	Pathogenic	0.898
OPA1	O60313-1.3	K797G	Pathogenic	0.919
OPA1	O60313-1.3	K797H	Pathogenic	0.818
OPA1	O60313-1.3	K797I	Pathogenic	0.893
OPA1	O60313-1.3	K797L	Pathogenic	0.76
OPA1	O60313-1.3	K797M	Pathogenic	0.627
OPA1	O60313-1.3	K797N	Pathogenic	0.736
OPA1	O60313-1.3	K797P	Pathogenic	0.703
OPA1	O60313-1.3	K797Q	Neutral	0.421
OPA1	O60313-1.3	K797R	Neutral	0.34
OPA1	O60313-1.3	K797S	Pathogenic	0.605
OPA1	O60313-1.3	K797T	Pathogenic	0.785
OPA1	O60313-1.3	K797V	Pathogenic	0.821
OPA1	O60313-1.3	K797W	Pathogenic	0.839
OPA1	O60313-1.3	K797Y	Pathogenic	0.864
OPA1	O60313-1.3	M798A	Neutral	0.184
OPA1	O60313-1.3	M798C	Neutral	0.31
OPA1	O60313-1.3	M798D	Neutral	0.436
OPA1	O60313-1.3	M798E	Neutral	0.244
OPA1	O60313-1.3	M798F	Neutral	0.115
OPA1	O60313-1.3	M798G	Pathogenic	0.572
OPA1	O60313-1.3	M798H	Neutral	0.403
OPA1	O60313-1.3	M798I	Neutral	0.044
OPA1	O60313-1.3	M798K	Neutral	0.076
OPA1	O60313-1.3	M798L	Neutral	0.017
OPA1	O60313-1.3	M798N	Neutral	0.241
OPA1	O60313-1.3	M798P	Pathogenic	0.51
OPA1	O60313-1.3	M798Q	Neutral	0.054
OPA1	O60313-1.3	M798R	Neutral	0.071
OPA1	O60313-1.3	M798S	Neutral	0.144
OPA1	O60313-1.3	M798T	Neutral	0.192
OPA1	O60313-1.3	M798V	Neutral	0.066
OPA1	O60313-1.3	M798W	Neutral	0.181
OPA1	O60313-1.3	M798Y	Neutral	0.323
OPA1	O60313-1.3	L799A	Pathogenic	0.711
OPA1	O60313-1.3	L799C	Pathogenic	0.83
OPA1	O60313-1.3	L799D	Pathogenic	0.961
OPA1	O60313-1.3	L799E	Pathogenic	0.91
OPA1	O60313-1.3	L799F	Pathogenic	0.769
OPA1	O60313-1.3	L799G	Pathogenic	0.977
OPA1	O60313-1.3	L799H	Pathogenic	0.955
OPA1	O60313-1.3	L799I	Neutral	0.289
OPA1	O60313-1.3	L799K	Pathogenic	0.72
OPA1	O60313-1.3	L799M	Neutral	0.225
OPA1	O60313-1.3	L799N	Pathogenic	0.909
OPA1	O60313-1.3	L799P	Pathogenic	0.97
OPA1	O60313-1.3	L799Q	Pathogenic	0.84
OPA1	O60313-1.3	L799R	Pathogenic	0.708
OPA1	O60313-1.3	L799S	Pathogenic	0.842
OPA1	O60313-1.3	L799T	Pathogenic	0.721
OPA1	O60313-1.3	L799V	Neutral	0.436
OPA1	O60313-1.3	L799W	Pathogenic	0.943
OPA1	O60313-1.3	L799Y	Pathogenic	0.838
OPA1	O60313-1.3	K800A	Pathogenic	0.66
OPA1	O60313-1.3	K800C	Pathogenic	0.904
OPA1	O60313-1.3	K800D	Pathogenic	0.851
OPA1	O60313-1.3	K800E	Neutral	0.391
OPA1	O60313-1.3	K800F	Pathogenic	0.844
OPA1	O60313-1.3	K800G	Pathogenic	0.874
OPA1	O60313-1.3	K800H	Pathogenic	0.734
OPA1	O60313-1.3	K800I	Pathogenic	0.837
OPA1	O60313-1.3	K800L	Pathogenic	0.661
OPA1	O60313-1.3	K800M	Pathogenic	0.508
OPA1	O60313-1.3	K800N	Pathogenic	0.632
OPA1	O60313-1.3	K800P	Pathogenic	0.593
OPA1	O60313-1.3	K800Q	Neutral	0.309
OPA1	O60313-1.3	K800R	Neutral	0.241
OPA1	O60313-1.3	K800S	Neutral	0.484
OPA1	O60313-1.3	K800T	Pathogenic	0.692
OPA1	O60313-1.3	K800V	Pathogenic	0.739
OPA1	O60313-1.3	K800W	Pathogenic	0.762
OPA1	O60313-1.3	K800Y	Pathogenic	0.796
OPA1	O60313-1.3	C801A	Neutral	0.051
OPA1	O60313-1.3	C801D	Neutral	0.34
OPA1	O60313-1.3	C801E	Pathogenic	0.612
OPA1	O60313-1.3	C801F	Neutral	0.264
OPA1	O60313-1.3	C801G	Neutral	0.48
OPA1	O60313-1.3	C801H	Pathogenic	0.516
OPA1	O60313-1.3	C801I	Neutral	0.113
OPA1	O60313-1.3	C801K	Neutral	0.263
OPA1	O60313-1.3	C801L	Neutral	0.123
OPA1	O60313-1.3	C801M	Neutral	0.177
OPA1	O60313-1.3	C801N	Neutral	0.371
OPA1	O60313-1.3	C801P	Pathogenic	0.669
OPA1	O60313-1.3	C801Q	Neutral	0.439
OPA1	O60313-1.3	C801R	Neutral	0.252
OPA1	O60313-1.3	C801S	Neutral	0.104
OPA1	O60313-1.3	C801T	Neutral	0.135
OPA1	O60313-1.3	C801V	Neutral	0.189
OPA1	O60313-1.3	C801W	Neutral	0.175
OPA1	O60313-1.3	C801Y	Neutral	0.418
OPA1	O60313-1.3	N802A	Neutral	0.438
OPA1	O60313-1.3	N802C	Pathogenic	0.566
OPA1	O60313-1.3	N802D	Neutral	0.064
OPA1	O60313-1.3	N802E	Neutral	0.179
OPA1	O60313-1.3	N802F	Neutral	0.359
OPA1	O60313-1.3	N802G	Neutral	0.103
OPA1	O60313-1.3	N802H	Neutral	0.037
OPA1	O60313-1.3	N802I	Neutral	0.365
OPA1	O60313-1.3	N802K	Neutral	0.126
OPA1	O60313-1.3	N802L	Neutral	0.388
OPA1	O60313-1.3	N802M	Neutral	0.251
OPA1	O60313-1.3	N802P	Neutral	0.368
OPA1	O60313-1.3	N802Q	Neutral	0.135
OPA1	O60313-1.3	N802R	Neutral	0.119
OPA1	O60313-1.3	N802S	Neutral	0.043
OPA1	O60313-1.3	N802T	Neutral	0.097
OPA1	O60313-1.3	N802V	Pathogenic	0.514
OPA1	O60313-1.3	N802W	Neutral	0.489
OPA1	O60313-1.3	N802Y	Neutral	0.287
OPA1	O60313-1.3	E803A	Neutral	0.227
OPA1	O60313-1.3	E803C	Pathogenic	0.806
OPA1	O60313-1.3	E803D	Neutral	0.027
OPA1	O60313-1.3	E803F	Neutral	0.404
OPA1	O60313-1.3	E803G	Pathogenic	0.513
OPA1	O60313-1.3	E803H	Neutral	0.119
OPA1	O60313-1.3	E803I	Neutral	0.41
OPA1	O60313-1.3	E803K	Neutral	0.06
OPA1	O60313-1.3	E803L	Neutral	0.433
OPA1	O60313-1.3	E803M	Neutral	0.288
OPA1	O60313-1.3	E803N	Neutral	0.206
OPA1	O60313-1.3	E803P	Neutral	0.18
OPA1	O60313-1.3	E803Q	Neutral	0.022
OPA1	O60313-1.3	E803R	Neutral	0.149
OPA1	O60313-1.3	E803S	Neutral	0.125
OPA1	O60313-1.3	E803T	Neutral	0.254
OPA1	O60313-1.3	E803V	Neutral	0.3
OPA1	O60313-1.3	E803W	Neutral	0.285
OPA1	O60313-1.3	E803Y	Neutral	0.328
OPA1	O60313-1.3	E804A	Neutral	0.215
OPA1	O60313-1.3	E804C	Pathogenic	0.794
OPA1	O60313-1.3	E804D	Neutral	0.025
OPA1	O60313-1.3	E804F	Neutral	0.386
OPA1	O60313-1.3	E804G	Neutral	0.495
OPA1	O60313-1.3	E804H	Neutral	0.111
OPA1	O60313-1.3	E804I	Neutral	0.393
OPA1	O60313-1.3	E804K	Neutral	0.056
OPA1	O60313-1.3	E804L	Neutral	0.416
OPA1	O60313-1.3	E804M	Neutral	0.274
OPA1	O60313-1.3	E804N	Neutral	0.195
OPA1	O60313-1.3	E804P	Neutral	0.17
OPA1	O60313-1.3	E804Q	Neutral	0.02
OPA1	O60313-1.3	E804R	Neutral	0.14
OPA1	O60313-1.3	E804S	Neutral	0.117
OPA1	O60313-1.3	E804T	Neutral	0.24
OPA1	O60313-1.3	E804V	Neutral	0.285
OPA1	O60313-1.3	E804W	Neutral	0.271
OPA1	O60313-1.3	E804Y	Neutral	0.312
OPA1	O60313-1.3	H805A	Pathogenic	0.999
OPA1	O60313-1.3	H805C	Pathogenic	0.999
OPA1	O60313-1.3	H805D	Pathogenic	0.994
OPA1	O60313-1.3	H805E	Pathogenic	0.986
OPA1	O60313-1.3	H805F	Pathogenic	0.989
OPA1	O60313-1.3	H805G	Pathogenic	0.999
OPA1	O60313-1.3	H805I	Pathogenic	0.999
OPA1	O60313-1.3	H805K	Pathogenic	0.993
OPA1	O60313-1.3	H805L	Pathogenic	0.999
OPA1	O60313-1.3	H805M	Pathogenic	0.998
OPA1	O60313-1.3	H805N	Pathogenic	0.961
OPA1	O60313-1.3	H805P	Pathogenic	0.998
OPA1	O60313-1.3	H805Q	Pathogenic	0.991
OPA1	O60313-1.3	H805R	Pathogenic	0.979
OPA1	O60313-1.3	H805S	Pathogenic	0.997
OPA1	O60313-1.3	H805T	Pathogenic	0.999
OPA1	O60313-1.3	H805V	Pathogenic	0.999
OPA1	O60313-1.3	H805W	Pathogenic	0.994
OPA1	O60313-1.3	H805Y	Pathogenic	0.885
OPA1	O60313-1.3	P806A	Neutral	0.123
OPA1	O60313-1.3	P806C	Pathogenic	0.592
OPA1	O60313-1.3	P806D	Neutral	0.054
OPA1	O60313-1.3	P806E	Neutral	0.057
OPA1	O60313-1.3	P806F	Pathogenic	0.633
OPA1	O60313-1.3	P806G	Neutral	0.223
OPA1	O60313-1.3	P806H	Neutral	0.254
OPA1	O60313-1.3	P806I	Neutral	0.38
OPA1	O60313-1.3	P806K	Neutral	0.038
OPA1	O60313-1.3	P806L	Neutral	0.402
OPA1	O60313-1.3	P806M	Neutral	0.263
OPA1	O60313-1.3	P806N	Neutral	0.159
OPA1	O60313-1.3	P806Q	Neutral	0.08
OPA1	O60313-1.3	P806R	Neutral	0.097
OPA1	O60313-1.3	P806S	Neutral	0.095
OPA1	O60313-1.3	P806T	Neutral	0.126
OPA1	O60313-1.3	P806V	Neutral	0.279
OPA1	O60313-1.3	P806W	Pathogenic	0.505
OPA1	O60313-1.3	P806Y	Pathogenic	0.554
OPA1	O60313-1.3	A807C	Pathogenic	0.695
OPA1	O60313-1.3	A807D	Pathogenic	0.929
OPA1	O60313-1.3	A807E	Pathogenic	0.826
OPA1	O60313-1.3	A807F	Pathogenic	0.884
OPA1	O60313-1.3	A807G	Pathogenic	0.761
OPA1	O60313-1.3	A807H	Pathogenic	0.964
OPA1	O60313-1.3	A807I	Pathogenic	0.73
OPA1	O60313-1.3	A807K	Pathogenic	0.757
OPA1	O60313-1.3	A807L	Pathogenic	0.748
OPA1	O60313-1.3	A807M	Pathogenic	0.82
OPA1	O60313-1.3	A807N	Pathogenic	0.937
OPA1	O60313-1.3	A807P	Pathogenic	0.892
OPA1	O60313-1.3	A807Q	Pathogenic	0.872
OPA1	O60313-1.3	A807R	Pathogenic	0.745
OPA1	O60313-1.3	A807S	Pathogenic	0.528
OPA1	O60313-1.3	A807T	Pathogenic	0.797
OPA1	O60313-1.3	A807V	Pathogenic	0.632
OPA1	O60313-1.3	A807W	Pathogenic	0.929
OPA1	O60313-1.3	A807Y	Pathogenic	0.941
OPA1	O60313-1.3	Y808A	Pathogenic	0.957
OPA1	O60313-1.3	Y808C	Pathogenic	0.977
OPA1	O60313-1.3	Y808D	Pathogenic	0.964
OPA1	O60313-1.3	Y808E	Pathogenic	0.917
OPA1	O60313-1.3	Y808F	Neutral	0.107
OPA1	O60313-1.3	Y808G	Pathogenic	0.979
OPA1	O60313-1.3	Y808H	Neutral	0.246
OPA1	O60313-1.3	Y808I	Pathogenic	0.889
OPA1	O60313-1.3	Y808K	Pathogenic	0.898
OPA1	O60313-1.3	Y808L	Pathogenic	0.898
OPA1	O60313-1.3	Y808M	Pathogenic	0.931
OPA1	O60313-1.3	Y808N	Pathogenic	0.916
OPA1	O60313-1.3	Y808P	Pathogenic	0.99
OPA1	O60313-1.3	Y808Q	Pathogenic	0.85
OPA1	O60313-1.3	Y808R	Pathogenic	0.896
OPA1	O60313-1.3	Y808S	Pathogenic	0.943
OPA1	O60313-1.3	Y808T	Pathogenic	0.959
OPA1	O60313-1.3	Y808V	Pathogenic	0.927
OPA1	O60313-1.3	Y808W	Neutral	0.177
OPA1	O60313-1.3	L809A	Pathogenic	0.972
OPA1	O60313-1.3	L809C	Pathogenic	0.986
OPA1	O60313-1.3	L809D	Pathogenic	0.997
OPA1	O60313-1.3	L809E	Pathogenic	0.993
OPA1	O60313-1.3	L809F	Pathogenic	0.979
OPA1	O60313-1.3	L809G	Pathogenic	0.998
OPA1	O60313-1.3	L809H	Pathogenic	0.997
OPA1	O60313-1.3	L809I	Pathogenic	0.851
OPA1	O60313-1.3	L809K	Pathogenic	0.973
OPA1	O60313-1.3	L809M	Pathogenic	0.803
OPA1	O60313-1.3	L809N	Pathogenic	0.993
OPA1	O60313-1.3	L809P	Pathogenic	0.998
OPA1	O60313-1.3	L809Q	Pathogenic	0.987
OPA1	O60313-1.3	L809R	Pathogenic	0.971
OPA1	O60313-1.3	L809S	Pathogenic	0.987
OPA1	O60313-1.3	L809T	Pathogenic	0.973
OPA1	O60313-1.3	L809V	Pathogenic	0.916
OPA1	O60313-1.3	L809W	Pathogenic	0.996
OPA1	O60313-1.3	L809Y	Pathogenic	0.986
OPA1	O60313-1.3	A810C	Pathogenic	0.578
OPA1	O60313-1.3	A810D	Pathogenic	0.887
OPA1	O60313-1.3	A810E	Pathogenic	0.74
OPA1	O60313-1.3	A810F	Pathogenic	0.821
OPA1	O60313-1.3	A810G	Pathogenic	0.657
OPA1	O60313-1.3	A810H	Pathogenic	0.942
OPA1	O60313-1.3	A810I	Pathogenic	0.619
OPA1	O60313-1.3	A810K	Pathogenic	0.652
OPA1	O60313-1.3	A810L	Pathogenic	0.641
OPA1	O60313-1.3	A810M	Pathogenic	0.733
OPA1	O60313-1.3	A810N	Pathogenic	0.9
OPA1	O60313-1.3	A810P	Pathogenic	0.833
OPA1	O60313-1.3	A810Q	Pathogenic	0.804
OPA1	O60313-1.3	A810R	Pathogenic	0.637
OPA1	O60313-1.3	A810S	Neutral	0.402
OPA1	O60313-1.3	A810T	Pathogenic	0.703
OPA1	O60313-1.3	A810V	Pathogenic	0.507
OPA1	O60313-1.3	A810W	Pathogenic	0.887
OPA1	O60313-1.3	A810Y	Pathogenic	0.905
OPA1	O60313-1.3	S811A	Neutral	0.014
OPA1	O60313-1.3	S811C	Neutral	0.059
OPA1	O60313-1.3	S811D	Neutral	0.027
OPA1	O60313-1.3	S811E	Neutral	0.028
OPA1	O60313-1.3	S811F	Neutral	0.067
OPA1	O60313-1.3	S811G	Neutral	0.048
OPA1	O60313-1.3	S811H	Neutral	0.108
OPA1	O60313-1.3	S811I	Neutral	0.069
OPA1	O60313-1.3	S811K	Neutral	0.019
OPA1	O60313-1.3	S811L	Neutral	0.075
OPA1	O60313-1.3	S811M	Neutral	0.041
OPA1	O60313-1.3	S811N	Neutral	0.011
OPA1	O60313-1.3	S811P	Neutral	0.073
OPA1	O60313-1.3	S811Q	Neutral	0.04
OPA1	O60313-1.3	S811R	Neutral	0.05
OPA1	O60313-1.3	S811T	Neutral	0.014
OPA1	O60313-1.3	S811V	Neutral	0.12
OPA1	O60313-1.3	S811W	Neutral	0.11
OPA1	O60313-1.3	S811Y	Neutral	0.131
OPA1	O60313-1.3	D812A	Pathogenic	0.989
OPA1	O60313-1.3	D812C	Pathogenic	0.993
OPA1	O60313-1.3	D812E	Pathogenic	0.755
OPA1	O60313-1.3	D812F	Pathogenic	0.984
OPA1	O60313-1.3	D812G	Pathogenic	0.975
OPA1	O60313-1.3	D812H	Pathogenic	0.973
OPA1	O60313-1.3	D812I	Pathogenic	0.985
OPA1	O60313-1.3	D812K	Pathogenic	0.984
OPA1	O60313-1.3	D812L	Pathogenic	0.995
OPA1	O60313-1.3	D812M	Pathogenic	0.991
OPA1	O60313-1.3	D812N	Pathogenic	0.901
OPA1	O60313-1.3	D812P	Pathogenic	0.959
OPA1	O60313-1.3	D812Q	Pathogenic	0.946
OPA1	O60313-1.3	D812R	Pathogenic	0.994
OPA1	O60313-1.3	D812S	Pathogenic	0.937
OPA1	O60313-1.3	D812T	Pathogenic	0.972
OPA1	O60313-1.3	D812V	Pathogenic	0.992
OPA1	O60313-1.3	D812W	Pathogenic	0.991
OPA1	O60313-1.3	D812Y	Pathogenic	0.992
OPA1	O60313-1.3	E813A	Pathogenic	0.983
OPA1	O60313-1.3	E813C	Pathogenic	0.999
OPA1	O60313-1.3	E813D	Pathogenic	0.848
OPA1	O60313-1.3	E813F	Pathogenic	0.993
OPA1	O60313-1.3	E813G	Pathogenic	0.995
OPA1	O60313-1.3	E813H	Pathogenic	0.964
OPA1	O60313-1.3	E813I	Pathogenic	0.993
OPA1	O60313-1.3	E813K	Pathogenic	0.928
OPA1	O60313-1.3	E813L	Pathogenic	0.994
OPA1	O60313-1.3	E813M	Pathogenic	0.988
OPA1	O60313-1.3	E813N	Pathogenic	0.981
OPA1	O60313-1.3	E813P	Pathogenic	0.978
OPA1	O60313-1.3	E813Q	Pathogenic	0.819
OPA1	O60313-1.3	E813R	Pathogenic	0.972
OPA1	O60313-1.3	E813S	Pathogenic	0.966
OPA1	O60313-1.3	E813T	Pathogenic	0.986
OPA1	O60313-1.3	E813V	Pathogenic	0.988
OPA1	O60313-1.3	E813W	Pathogenic	0.988
OPA1	O60313-1.3	E813Y	Pathogenic	0.99
OPA1	O60313-1.3	I814A	Neutral	0.098
OPA1	O60313-1.3	I814C	Neutral	0.179
OPA1	O60313-1.3	I814D	Neutral	0.272
OPA1	O60313-1.3	I814E	Neutral	0.311
OPA1	O60313-1.3	I814F	Neutral	0.148
OPA1	O60313-1.3	I814G	Pathogenic	0.652
OPA1	O60313-1.3	I814H	Neutral	0.486
OPA1	O60313-1.3	I814K	Neutral	0.249
OPA1	O60313-1.3	I814L	Neutral	0.019
OPA1	O60313-1.3	I814M	Neutral	0.036
OPA1	O60313-1.3	I814N	Neutral	0.308
OPA1	O60313-1.3	I814P	Pathogenic	0.593
OPA1	O60313-1.3	I814Q	Neutral	0.403
OPA1	O60313-1.3	I814R	Neutral	0.238
OPA1	O60313-1.3	I814S	Neutral	0.191
OPA1	O60313-1.3	I814T	Neutral	0.103
OPA1	O60313-1.3	I814V	Neutral	0.004
OPA1	O60313-1.3	I814W	Pathogenic	0.719
OPA1	O60313-1.3	I814Y	Neutral	0.187
OPA1	O60313-1.3	T815A	Pathogenic	0.984
OPA1	O60313-1.3	T815C	Pathogenic	0.99
OPA1	O60313-1.3	T815D	Pathogenic	0.987
OPA1	O60313-1.3	T815E	Pathogenic	0.988
OPA1	O60313-1.3	T815F	Pathogenic	0.992
OPA1	O60313-1.3	T815G	Pathogenic	0.997
OPA1	O60313-1.3	T815H	Pathogenic	0.998
OPA1	O60313-1.3	T815I	Pathogenic	0.978
OPA1	O60313-1.3	T815K	Pathogenic	0.982
OPA1	O60313-1.3	T815L	Pathogenic	0.98
OPA1	O60313-1.3	T815M	Pathogenic	0.987
OPA1	O60313-1.3	T815N	Pathogenic	0.969
OPA1	O60313-1.3	T815P	Pathogenic	0.992
OPA1	O60313-1.3	T815Q	Pathogenic	0.992
OPA1	O60313-1.3	T815R	Pathogenic	0.981
OPA1	O60313-1.3	T815S	Pathogenic	0.945
OPA1	O60313-1.3	T815V	Pathogenic	0.965
OPA1	O60313-1.3	T815W	Pathogenic	0.986
OPA1	O60313-1.3	T815Y	Pathogenic	0.996
OPA1	O60313-1.3	T816A	Pathogenic	0.972
OPA1	O60313-1.3	T816C	Pathogenic	0.983
OPA1	O60313-1.3	T816D	Pathogenic	0.978
OPA1	O60313-1.3	T816E	Pathogenic	0.979
OPA1	O60313-1.3	T816F	Pathogenic	0.986
OPA1	O60313-1.3	T816G	Pathogenic	0.996
OPA1	O60313-1.3	T816H	Pathogenic	0.996
OPA1	O60313-1.3	T816I	Pathogenic	0.961
OPA1	O60313-1.3	T816K	Pathogenic	0.969
OPA1	O60313-1.3	T816L	Pathogenic	0.964
OPA1	O60313-1.3	T816M	Pathogenic	0.977
OPA1	O60313-1.3	T816N	Pathogenic	0.947
OPA1	O60313-1.3	T816P	Pathogenic	0.987
OPA1	O60313-1.3	T816Q	Pathogenic	0.986
OPA1	O60313-1.3	T816R	Pathogenic	0.967
OPA1	O60313-1.3	T816S	Pathogenic	0.906
OPA1	O60313-1.3	T816V	Pathogenic	0.94
OPA1	O60313-1.3	T816W	Pathogenic	0.976
OPA1	O60313-1.3	T816Y	Pathogenic	0.993
OPA1	O60313-1.3	V817A	Pathogenic	0.898
OPA1	O60313-1.3	V817C	Pathogenic	0.981
OPA1	O60313-1.3	V817D	Pathogenic	0.989
OPA1	O60313-1.3	V817E	Pathogenic	0.973
OPA1	O60313-1.3	V817F	Pathogenic	0.973
OPA1	O60313-1.3	V817G	Pathogenic	0.993
OPA1	O60313-1.3	V817H	Pathogenic	0.995
OPA1	O60313-1.3	V817I	Neutral	0.343
OPA1	O60313-1.3	V817K	Pathogenic	0.959
OPA1	O60313-1.3	V817L	Pathogenic	0.828
OPA1	O60313-1.3	V817M	Pathogenic	0.881
OPA1	O60313-1.3	V817N	Pathogenic	0.99
OPA1	O60313-1.3	V817P	Pathogenic	0.992
OPA1	O60313-1.3	V817Q	Pathogenic	0.981
OPA1	O60313-1.3	V817R	Pathogenic	0.984
OPA1	O60313-1.3	V817S	Pathogenic	0.982
OPA1	O60313-1.3	V817T	Pathogenic	0.903
OPA1	O60313-1.3	V817W	Pathogenic	0.994
OPA1	O60313-1.3	V817Y	Pathogenic	0.979
OPA1	O60313-1.3	R818A	Pathogenic	0.976
OPA1	O60313-1.3	R818C	Pathogenic	0.995
OPA1	O60313-1.3	R818D	Pathogenic	0.997
OPA1	O60313-1.3	R818E	Pathogenic	0.975
OPA1	O60313-1.3	R818F	Pathogenic	0.991
OPA1	O60313-1.3	R818G	Pathogenic	0.993
OPA1	O60313-1.3	R818H	Pathogenic	0.953
OPA1	O60313-1.3	R818I	Pathogenic	0.991
OPA1	O60313-1.3	R818K	Pathogenic	0.878
OPA1	O60313-1.3	R818L	Pathogenic	0.976
OPA1	O60313-1.3	R818M	Pathogenic	0.956
OPA1	O60313-1.3	R818N	Pathogenic	0.973
OPA1	O60313-1.3	R818P	Pathogenic	0.989
OPA1	O60313-1.3	R818Q	Pathogenic	0.905
OPA1	O60313-1.3	R818S	Pathogenic	0.983
OPA1	O60313-1.3	R818T	Pathogenic	0.979
OPA1	O60313-1.3	R818V	Pathogenic	0.994
OPA1	O60313-1.3	R818W	Pathogenic	0.987
OPA1	O60313-1.3	R818Y	Pathogenic	0.989
OPA1	O60313-1.3	K819A	Pathogenic	0.975
OPA1	O60313-1.3	K819C	Pathogenic	0.995
OPA1	O60313-1.3	K819D	Pathogenic	0.991
OPA1	O60313-1.3	K819E	Pathogenic	0.929
OPA1	O60313-1.3	K819F	Pathogenic	0.991
OPA1	O60313-1.3	K819G	Pathogenic	0.993
OPA1	O60313-1.3	K819H	Pathogenic	0.982
OPA1	O60313-1.3	K819I	Pathogenic	0.991
OPA1	O60313-1.3	K819L	Pathogenic	0.975
OPA1	O60313-1.3	K819M	Pathogenic	0.954
OPA1	O60313-1.3	K819N	Pathogenic	0.972
OPA1	O60313-1.3	K819P	Pathogenic	0.967
OPA1	O60313-1.3	K819Q	Pathogenic	0.901
OPA1	O60313-1.3	K819R	Pathogenic	0.865
OPA1	O60313-1.3	K819S	Pathogenic	0.95
OPA1	O60313-1.3	K819T	Pathogenic	0.979
OPA1	O60313-1.3	K819V	Pathogenic	0.983
OPA1	O60313-1.3	K819W	Pathogenic	0.985
OPA1	O60313-1.3	K819Y	Pathogenic	0.988
OPA1	O60313-1.3	N820A	Pathogenic	0.996
OPA1	O60313-1.3	N820C	Pathogenic	0.998
OPA1	O60313-1.3	N820D	Pathogenic	0.958
OPA1	O60313-1.3	N820E	Pathogenic	0.986
OPA1	O60313-1.3	N820F	Pathogenic	0.995
OPA1	O60313-1.3	N820G	Pathogenic	0.974
OPA1	O60313-1.3	N820H	Pathogenic	0.927
OPA1	O60313-1.3	N820I	Pathogenic	0.995
OPA1	O60313-1.3	N820K	Pathogenic	0.979
OPA1	O60313-1.3	N820L	Pathogenic	0.995
OPA1	O60313-1.3	N820M	Pathogenic	0.991
OPA1	O60313-1.3	N820P	Pathogenic	0.995
OPA1	O60313-1.3	N820Q	Pathogenic	0.981
OPA1	O60313-1.3	N820R	Pathogenic	0.978
OPA1	O60313-1.3	N820S	Pathogenic	0.937
OPA1	O60313-1.3	N820T	Pathogenic	0.973
OPA1	O60313-1.3	N820V	Pathogenic	0.997
OPA1	O60313-1.3	N820W	Pathogenic	0.997
OPA1	O60313-1.3	N820Y	Pathogenic	0.993
OPA1	O60313-1.3	L821A	Pathogenic	0.927
OPA1	O60313-1.3	L821C	Pathogenic	0.962
OPA1	O60313-1.3	L821D	Pathogenic	0.992
OPA1	O60313-1.3	L821E	Pathogenic	0.981
OPA1	O60313-1.3	L821F	Pathogenic	0.945
OPA1	O60313-1.3	L821G	Pathogenic	0.995
OPA1	O60313-1.3	L821H	Pathogenic	0.991
OPA1	O60313-1.3	L821I	Pathogenic	0.678
OPA1	O60313-1.3	L821K	Pathogenic	0.93
OPA1	O60313-1.3	L821M	Pathogenic	0.6
OPA1	O60313-1.3	L821N	Pathogenic	0.981
OPA1	O60313-1.3	L821P	Pathogenic	0.994
OPA1	O60313-1.3	L821Q	Pathogenic	0.964
OPA1	O60313-1.3	L821R	Pathogenic	0.926
OPA1	O60313-1.3	L821S	Pathogenic	0.965
OPA1	O60313-1.3	L821T	Pathogenic	0.93
OPA1	O60313-1.3	L821V	Pathogenic	0.8
OPA1	O60313-1.3	L821W	Pathogenic	0.988
OPA1	O60313-1.3	L821Y	Pathogenic	0.964
OPA1	O60313-1.3	E822A	Pathogenic	0.799
OPA1	O60313-1.3	E822C	Pathogenic	0.983
OPA1	O60313-1.3	E822D	Neutral	0.274
OPA1	O60313-1.3	E822F	Pathogenic	0.902
OPA1	O60313-1.3	E822G	Pathogenic	0.934
OPA1	O60313-1.3	E822H	Pathogenic	0.646
OPA1	O60313-1.3	E822I	Pathogenic	0.904
OPA1	O60313-1.3	E822K	Neutral	0.464
OPA1	O60313-1.3	E822L	Pathogenic	0.912
OPA1	O60313-1.3	E822M	Pathogenic	0.846
OPA1	O60313-1.3	E822N	Pathogenic	0.779
OPA1	O60313-1.3	E822P	Pathogenic	0.749
OPA1	O60313-1.3	E822Q	Neutral	0.233
OPA1	O60313-1.3	E822R	Pathogenic	0.703
OPA1	O60313-1.3	E822S	Pathogenic	0.658
OPA1	O60313-1.3	E822T	Pathogenic	0.822
OPA1	O60313-1.3	E822V	Pathogenic	0.853
OPA1	O60313-1.3	E822W	Pathogenic	0.844
OPA1	O60313-1.3	E822Y	Pathogenic	0.868
OPA1	O60313-1.3	S823A	Neutral	0.02
OPA1	O60313-1.3	S823C	Neutral	0.081
OPA1	O60313-1.3	S823D	Neutral	0.037
OPA1	O60313-1.3	S823E	Neutral	0.039
OPA1	O60313-1.3	S823F	Neutral	0.092
OPA1	O60313-1.3	S823G	Neutral	0.067
OPA1	O60313-1.3	S823H	Neutral	0.145
OPA1	O60313-1.3	S823I	Neutral	0.095
OPA1	O60313-1.3	S823K	Neutral	0.026
OPA1	O60313-1.3	S823L	Neutral	0.103
OPA1	O60313-1.3	S823M	Neutral	0.057
OPA1	O60313-1.3	S823N	Neutral	0.015
OPA1	O60313-1.3	S823P	Neutral	0.099
OPA1	O60313-1.3	S823Q	Neutral	0.056
OPA1	O60313-1.3	S823R	Neutral	0.068
OPA1	O60313-1.3	S823T	Neutral	0.019
OPA1	O60313-1.3	S823V	Neutral	0.161
OPA1	O60313-1.3	S823W	Neutral	0.148
OPA1	O60313-1.3	S823Y	Neutral	0.175
OPA1	O60313-1.3	R824A	Neutral	0.232
OPA1	O60313-1.3	R824C	Pathogenic	0.596
OPA1	O60313-1.3	R824D	Pathogenic	0.72
OPA1	O60313-1.3	R824E	Neutral	0.225
OPA1	O60313-1.3	R824F	Neutral	0.458
OPA1	O60313-1.3	R824G	Pathogenic	0.52
OPA1	O60313-1.3	R824H	Neutral	0.129
OPA1	O60313-1.3	R824I	Neutral	0.445
OPA1	O60313-1.3	R824K	Neutral	0.05
OPA1	O60313-1.3	R824L	Neutral	0.233
OPA1	O60313-1.3	R824M	Neutral	0.138
OPA1	O60313-1.3	R824N	Neutral	0.211
OPA1	O60313-1.3	R824P	Neutral	0.396
OPA1	O60313-1.3	R824Q	Neutral	0.065
OPA1	O60313-1.3	R824S	Neutral	0.298
OPA1	O60313-1.3	R824T	Neutral	0.259
OPA1	O60313-1.3	R824V	Pathogenic	0.561
OPA1	O60313-1.3	R824W	Neutral	0.355
OPA1	O60313-1.3	R824Y	Neutral	0.389
OPA1	O60313-1.3	G825A	Pathogenic	0.934
OPA1	O60313-1.3	G825C	Pathogenic	0.994
OPA1	O60313-1.3	G825D	Pathogenic	0.961
OPA1	O60313-1.3	G825E	Pathogenic	0.987
OPA1	O60313-1.3	G825F	Pathogenic	0.986
OPA1	O60313-1.3	G825H	Pathogenic	0.991
OPA1	O60313-1.3	G825I	Pathogenic	0.995
OPA1	O60313-1.3	G825K	Pathogenic	0.98
OPA1	O60313-1.3	G825L	Pathogenic	0.996
OPA1	O60313-1.3	G825M	Pathogenic	0.992
OPA1	O60313-1.3	G825N	Pathogenic	0.906
OPA1	O60313-1.3	G825P	Pathogenic	0.987
OPA1	O60313-1.3	G825Q	Pathogenic	0.991
OPA1	O60313-1.3	G825R	Pathogenic	0.979
OPA1	O60313-1.3	G825S	Pathogenic	0.946
OPA1	O60313-1.3	G825T	Pathogenic	0.991
OPA1	O60313-1.3	G825V	Pathogenic	0.992
OPA1	O60313-1.3	G825W	Pathogenic	0.933
OPA1	O60313-1.3	G825Y	Pathogenic	0.993
OPA1	O60313-1.3	V826A	Neutral	0.257
OPA1	O60313-1.3	V826C	Pathogenic	0.666
OPA1	O60313-1.3	V826D	Pathogenic	0.775
OPA1	O60313-1.3	V826E	Pathogenic	0.581
OPA1	O60313-1.3	V826F	Pathogenic	0.584
OPA1	O60313-1.3	V826G	Pathogenic	0.856
OPA1	O60313-1.3	V826H	Pathogenic	0.887
OPA1	O60313-1.3	V826I	Neutral	0.02
OPA1	O60313-1.3	V826K	Neutral	0.477
OPA1	O60313-1.3	V826L	Neutral	0.159
OPA1	O60313-1.3	V826M	Neutral	0.225
OPA1	O60313-1.3	V826N	Pathogenic	0.803
OPA1	O60313-1.3	V826P	Pathogenic	0.822
OPA1	O60313-1.3	V826Q	Pathogenic	0.666
OPA1	O60313-1.3	V826R	Pathogenic	0.713
OPA1	O60313-1.3	V826S	Pathogenic	0.684
OPA1	O60313-1.3	V826T	Neutral	0.267
OPA1	O60313-1.3	V826W	Pathogenic	0.875
OPA1	O60313-1.3	V826Y	Pathogenic	0.647
OPA1	O60313-1.3	E827A	Neutral	0.274
OPA1	O60313-1.3	E827C	Pathogenic	0.842
OPA1	O60313-1.3	E827D	Neutral	0.034
OPA1	O60313-1.3	E827F	Neutral	0.464
OPA1	O60313-1.3	E827G	Pathogenic	0.574
OPA1	O60313-1.3	E827H	Neutral	0.147
OPA1	O60313-1.3	E827I	Neutral	0.471
OPA1	O60313-1.3	E827K	Neutral	0.076
OPA1	O60313-1.3	E827L	Neutral	0.495
OPA1	O60313-1.3	E827M	Neutral	0.341
OPA1	O60313-1.3	E827N	Neutral	0.25
OPA1	O60313-1.3	E827P	Neutral	0.22
OPA1	O60313-1.3	E827Q	Neutral	0.028
OPA1	O60313-1.3	E827R	Neutral	0.183
OPA1	O60313-1.3	E827S	Neutral	0.154
OPA1	O60313-1.3	E827T	Neutral	0.303
OPA1	O60313-1.3	E827V	Neutral	0.354
OPA1	O60313-1.3	E827W	Neutral	0.338
OPA1	O60313-1.3	E827Y	Neutral	0.384
OPA1	O60313-1.3	V828A	Pathogenic	0.89
OPA1	O60313-1.3	V828C	Pathogenic	0.979
OPA1	O60313-1.3	V828D	Pathogenic	0.988
OPA1	O60313-1.3	V828E	Pathogenic	0.97
OPA1	O60313-1.3	V828F	Pathogenic	0.97
OPA1	O60313-1.3	V828G	Pathogenic	0.993
OPA1	O60313-1.3	V828H	Pathogenic	0.995
OPA1	O60313-1.3	V828I	Neutral	0.323
OPA1	O60313-1.3	V828K	Pathogenic	0.955
OPA1	O60313-1.3	V828L	Pathogenic	0.815
OPA1	O60313-1.3	V828M	Pathogenic	0.871
OPA1	O60313-1.3	V828N	Pathogenic	0.99
OPA1	O60313-1.3	V828P	Pathogenic	0.991
OPA1	O60313-1.3	V828Q	Pathogenic	0.979
OPA1	O60313-1.3	V828R	Pathogenic	0.983
OPA1	O60313-1.3	V828S	Pathogenic	0.981
OPA1	O60313-1.3	V828T	Pathogenic	0.894
OPA1	O60313-1.3	V828W	Pathogenic	0.994
OPA1	O60313-1.3	V828Y	Pathogenic	0.977
OPA1	O60313-1.3	D829A	Pathogenic	0.995
OPA1	O60313-1.3	D829C	Pathogenic	0.997
OPA1	O60313-1.3	D829E	Pathogenic	0.867
OPA1	O60313-1.3	D829F	Pathogenic	0.992
OPA1	O60313-1.3	D829G	Pathogenic	0.988
OPA1	O60313-1.3	D829H	Pathogenic	0.987
OPA1	O60313-1.3	D829I	Pathogenic	0.993
OPA1	O60313-1.3	D829K	Pathogenic	0.993
OPA1	O60313-1.3	D829L	Pathogenic	0.998
OPA1	O60313-1.3	D829M	Pathogenic	0.996
OPA1	O60313-1.3	D829N	Pathogenic	0.95
OPA1	O60313-1.3	D829P	Pathogenic	0.98
OPA1	O60313-1.3	D829Q	Pathogenic	0.973
OPA1	O60313-1.3	D829R	Pathogenic	0.997
OPA1	O60313-1.3	D829S	Pathogenic	0.969
OPA1	O60313-1.3	D829T	Pathogenic	0.987
OPA1	O60313-1.3	D829V	Pathogenic	0.996
OPA1	O60313-1.3	D829W	Pathogenic	0.996
OPA1	O60313-1.3	D829Y	Pathogenic	0.996
OPA1	O60313-1.3	P830A	Pathogenic	0.745
OPA1	O60313-1.3	P830C	Pathogenic	0.968
OPA1	O60313-1.3	P830D	Pathogenic	0.541
OPA1	O60313-1.3	P830E	Pathogenic	0.555
OPA1	O60313-1.3	P830F	Pathogenic	0.973
OPA1	O60313-1.3	P830G	Pathogenic	0.856
OPA1	O60313-1.3	P830H	Pathogenic	0.876
OPA1	O60313-1.3	P830I	Pathogenic	0.927
OPA1	O60313-1.3	P830K	Neutral	0.45
OPA1	O60313-1.3	P830L	Pathogenic	0.933
OPA1	O60313-1.3	P830M	Pathogenic	0.881
OPA1	O60313-1.3	P830N	Pathogenic	0.797
OPA1	O60313-1.3	P830Q	Pathogenic	0.642
OPA1	O60313-1.3	P830R	Pathogenic	0.691
OPA1	O60313-1.3	P830S	Pathogenic	0.685
OPA1	O60313-1.3	P830T	Pathogenic	0.75
OPA1	O60313-1.3	P830V	Pathogenic	0.889
OPA1	O60313-1.3	P830W	Pathogenic	0.955
OPA1	O60313-1.3	P830Y	Pathogenic	0.963
OPA1	O60313-1.3	S831A	Neutral	0.001
OPA1	O60313-1.3	S831C	Neutral	0.004
OPA1	O60313-1.3	S831D	Neutral	0.002
OPA1	O60313-1.3	S831E	Neutral	0.002
OPA1	O60313-1.3	S831F	Neutral	0.005
OPA1	O60313-1.3	S831G	Neutral	0.004
OPA1	O60313-1.3	S831H	Neutral	0.009
OPA1	O60313-1.3	S831I	Neutral	0.005
OPA1	O60313-1.3	S831K	Neutral	0.001
OPA1	O60313-1.3	S831L	Neutral	0.006
OPA1	O60313-1.3	S831M	Neutral	0.003
OPA1	O60313-1.3	S831N	Neutral	0.001
OPA1	O60313-1.3	S831P	Neutral	0.006
OPA1	O60313-1.3	S831Q	Neutral	0.003
OPA1	O60313-1.3	S831R	Neutral	0.004
OPA1	O60313-1.3	S831T	Neutral	0.001
OPA1	O60313-1.3	S831V	Neutral	0.01
OPA1	O60313-1.3	S831W	Neutral	0.009
OPA1	O60313-1.3	S831Y	Neutral	0.011
OPA1	O60313-1.3	L832A	Pathogenic	0.6
OPA1	O60313-1.3	L832C	Pathogenic	0.749
OPA1	O60313-1.3	L832D	Pathogenic	0.937
OPA1	O60313-1.3	L832E	Pathogenic	0.861
OPA1	O60313-1.3	L832F	Pathogenic	0.67
OPA1	O60313-1.3	L832G	Pathogenic	0.962
OPA1	O60313-1.3	L832H	Pathogenic	0.928
OPA1	O60313-1.3	L832I	Neutral	0.199
OPA1	O60313-1.3	L832K	Pathogenic	0.611
OPA1	O60313-1.3	L832M	Neutral	0.151
OPA1	O60313-1.3	L832N	Pathogenic	0.859
OPA1	O60313-1.3	L832P	Pathogenic	0.952
OPA1	O60313-1.3	L832Q	Pathogenic	0.762
OPA1	O60313-1.3	L832R	Pathogenic	0.596
OPA1	O60313-1.3	L832S	Pathogenic	0.764
OPA1	O60313-1.3	L832T	Pathogenic	0.612
OPA1	O60313-1.3	L832V	Neutral	0.321
OPA1	O60313-1.3	L832W	Pathogenic	0.91
OPA1	O60313-1.3	L832Y	Pathogenic	0.76
OPA1	O60313-1.3	I833A	Pathogenic	0.976
OPA1	O60313-1.3	I833C	Pathogenic	0.988
OPA1	O60313-1.3	I833D	Pathogenic	0.993
OPA1	O60313-1.3	I833E	Pathogenic	0.994
OPA1	O60313-1.3	I833F	Pathogenic	0.985
OPA1	O60313-1.3	I833G	Pathogenic	0.999
OPA1	O60313-1.3	I833H	Pathogenic	0.997
OPA1	O60313-1.3	I833K	Pathogenic	0.992
OPA1	O60313-1.3	I833L	Pathogenic	0.882
OPA1	O60313-1.3	I833M	Pathogenic	0.934
OPA1	O60313-1.3	I833N	Pathogenic	0.994
OPA1	O60313-1.3	I833P	Pathogenic	0.998
OPA1	O60313-1.3	I833Q	Pathogenic	0.996
OPA1	O60313-1.3	I833R	Pathogenic	0.992
OPA1	O60313-1.3	I833S	Pathogenic	0.989
OPA1	O60313-1.3	I833T	Pathogenic	0.977
OPA1	O60313-1.3	I833V	Pathogenic	0.607
OPA1	O60313-1.3	I833W	Pathogenic	0.999
OPA1	O60313-1.3	I833Y	Pathogenic	0.989
OPA1	O60313-1.3	K834A	Pathogenic	0.724
OPA1	O60313-1.3	K834C	Pathogenic	0.927
OPA1	O60313-1.3	K834D	Pathogenic	0.885
OPA1	O60313-1.3	K834E	Neutral	0.465
OPA1	O60313-1.3	K834F	Pathogenic	0.88
OPA1	O60313-1.3	K834G	Pathogenic	0.904
OPA1	O60313-1.3	K834H	Pathogenic	0.789
OPA1	O60313-1.3	K834I	Pathogenic	0.874
OPA1	O60313-1.3	K834L	Pathogenic	0.725
OPA1	O60313-1.3	K834M	Pathogenic	0.583
OPA1	O60313-1.3	K834N	Pathogenic	0.699
OPA1	O60313-1.3	K834P	Pathogenic	0.663
OPA1	O60313-1.3	K834Q	Neutral	0.377
OPA1	O60313-1.3	K834R	Neutral	0.3
OPA1	O60313-1.3	K834S	Pathogenic	0.56
OPA1	O60313-1.3	K834T	Pathogenic	0.752
OPA1	O60313-1.3	K834V	Pathogenic	0.793
OPA1	O60313-1.3	K834W	Pathogenic	0.812
OPA1	O60313-1.3	K834Y	Pathogenic	0.841
OPA1	O60313-1.3	D835A	Pathogenic	0.911
OPA1	O60313-1.3	D835C	Pathogenic	0.945
OPA1	O60313-1.3	D835E	Neutral	0.261
OPA1	O60313-1.3	D835F	Pathogenic	0.877
OPA1	O60313-1.3	D835G	Pathogenic	0.814
OPA1	O60313-1.3	D835H	Pathogenic	0.805
OPA1	O60313-1.3	D835I	Pathogenic	0.88
OPA1	O60313-1.3	D835K	Pathogenic	0.878
OPA1	O60313-1.3	D835L	Pathogenic	0.959
OPA1	O60313-1.3	D835M	Pathogenic	0.925
OPA1	O60313-1.3	D835N	Pathogenic	0.51
OPA1	O60313-1.3	D835P	Pathogenic	0.726
OPA1	O60313-1.3	D835Q	Pathogenic	0.666
OPA1	O60313-1.3	D835R	Pathogenic	0.952
OPA1	O60313-1.3	D835S	Pathogenic	0.632
OPA1	O60313-1.3	D835T	Pathogenic	0.802
OPA1	O60313-1.3	D835V	Pathogenic	0.931
OPA1	O60313-1.3	D835W	Pathogenic	0.924
OPA1	O60313-1.3	D835Y	Pathogenic	0.937
OPA1	O60313-1.3	T836A	Pathogenic	0.983
OPA1	O60313-1.3	T836C	Pathogenic	0.99
OPA1	O60313-1.3	T836D	Pathogenic	0.987
OPA1	O60313-1.3	T836E	Pathogenic	0.988
OPA1	O60313-1.3	T836F	Pathogenic	0.992
OPA1	O60313-1.3	T836G	Pathogenic	0.997
OPA1	O60313-1.3	T836H	Pathogenic	0.998
OPA1	O60313-1.3	T836I	Pathogenic	0.977
OPA1	O60313-1.3	T836K	Pathogenic	0.982
OPA1	O60313-1.3	T836L	Pathogenic	0.979
OPA1	O60313-1.3	T836M	Pathogenic	0.986
OPA1	O60313-1.3	T836N	Pathogenic	0.969
OPA1	O60313-1.3	T836P	Pathogenic	0.992
OPA1	O60313-1.3	T836Q	Pathogenic	0.992
OPA1	O60313-1.3	T836R	Pathogenic	0.981
OPA1	O60313-1.3	T836S	Pathogenic	0.944
OPA1	O60313-1.3	T836V	Pathogenic	0.965
OPA1	O60313-1.3	T836W	Pathogenic	0.986
OPA1	O60313-1.3	T836Y	Pathogenic	0.996
OPA1	O60313-1.3	W837A	Pathogenic	0.997
OPA1	O60313-1.3	W837C	Pathogenic	0.995
OPA1	O60313-1.3	W837D	Pathogenic	0.997
OPA1	O60313-1.3	W837E	Pathogenic	0.993
OPA1	O60313-1.3	W837F	Pathogenic	0.956
OPA1	O60313-1.3	W837G	Pathogenic	0.987
OPA1	O60313-1.3	W837H	Pathogenic	0.991
OPA1	O60313-1.3	W837I	Pathogenic	0.999
OPA1	O60313-1.3	W837K	Pathogenic	0.992
OPA1	O60313-1.3	W837L	Pathogenic	0.998
OPA1	O60313-1.3	W837M	Pathogenic	0.991
OPA1	O60313-1.3	W837N	Pathogenic	0.998
OPA1	O60313-1.3	W837P	Pathogenic	0.999
OPA1	O60313-1.3	W837Q	Pathogenic	0.987
OPA1	O60313-1.3	W837R	Pathogenic	0.992
OPA1	O60313-1.3	W837S	Pathogenic	0.996
OPA1	O60313-1.3	W837T	Pathogenic	0.991
OPA1	O60313-1.3	W837V	Pathogenic	0.999
OPA1	O60313-1.3	W837Y	Pathogenic	0.783
OPA1	O60313-1.3	H838A	Pathogenic	0.991
OPA1	O60313-1.3	H838C	Pathogenic	0.995
OPA1	O60313-1.3	H838D	Pathogenic	0.955
OPA1	O60313-1.3	H838E	Pathogenic	0.898
OPA1	O60313-1.3	H838F	Pathogenic	0.916
OPA1	O60313-1.3	H838G	Pathogenic	0.991
OPA1	O60313-1.3	H838I	Pathogenic	0.99
OPA1	O60313-1.3	H838K	Pathogenic	0.947
OPA1	O60313-1.3	H838L	Pathogenic	0.99
OPA1	O60313-1.3	H838M	Pathogenic	0.982
OPA1	O60313-1.3	H838N	Pathogenic	0.749
OPA1	O60313-1.3	H838P	Pathogenic	0.988
OPA1	O60313-1.3	H838Q	Pathogenic	0.929
OPA1	O60313-1.3	H838R	Pathogenic	0.853
OPA1	O60313-1.3	H838S	Pathogenic	0.975
OPA1	O60313-1.3	H838T	Pathogenic	0.992
OPA1	O60313-1.3	H838V	Pathogenic	0.994
OPA1	O60313-1.3	H838W	Pathogenic	0.949
OPA1	O60313-1.3	H838Y	Neutral	0.484
OPA1	O60313-1.3	Q839A	Pathogenic	0.875
OPA1	O60313-1.3	Q839C	Pathogenic	0.971
OPA1	O60313-1.3	Q839D	Pathogenic	0.721
OPA1	O60313-1.3	Q839E	Neutral	0.271
OPA1	O60313-1.3	Q839F	Pathogenic	0.944
OPA1	O60313-1.3	Q839G	Pathogenic	0.962
OPA1	O60313-1.3	Q839H	Pathogenic	0.769
OPA1	O60313-1.3	Q839I	Pathogenic	0.945
OPA1	O60313-1.3	Q839K	Neutral	0.424
OPA1	O60313-1.3	Q839L	Pathogenic	0.867
OPA1	O60313-1.3	Q839M	Pathogenic	0.543
OPA1	O60313-1.3	Q839N	Pathogenic	0.755
OPA1	O60313-1.3	Q839P	Pathogenic	0.84
OPA1	O60313-1.3	Q839R	Neutral	0.409
OPA1	O60313-1.3	Q839S	Pathogenic	0.772
OPA1	O60313-1.3	Q839T	Pathogenic	0.89
OPA1	O60313-1.3	Q839V	Pathogenic	0.911
OPA1	O60313-1.3	Q839W	Pathogenic	0.773
OPA1	O60313-1.3	Q839Y	Pathogenic	0.806
OPA1	O60313-1.3	V840A	Neutral	0.121
OPA1	O60313-1.3	V840C	Neutral	0.443
OPA1	O60313-1.3	V840D	Pathogenic	0.578
OPA1	O60313-1.3	V840E	Neutral	0.356
OPA1	O60313-1.3	V840F	Neutral	0.359
OPA1	O60313-1.3	V840G	Pathogenic	0.702
OPA1	O60313-1.3	V840H	Pathogenic	0.758
OPA1	O60313-1.3	V840I	Neutral	0.008
OPA1	O60313-1.3	V840K	Neutral	0.267
OPA1	O60313-1.3	V840L	Neutral	0.07
OPA1	O60313-1.3	V840M	Neutral	0.104
OPA1	O60313-1.3	V840N	Pathogenic	0.619
OPA1	O60313-1.3	V840P	Pathogenic	0.647
OPA1	O60313-1.3	V840Q	Neutral	0.443
OPA1	O60313-1.3	V840R	Neutral	0.498
OPA1	O60313-1.3	V840S	Neutral	0.463
OPA1	O60313-1.3	V840T	Neutral	0.126
OPA1	O60313-1.3	V840W	Pathogenic	0.735
OPA1	O60313-1.3	V840Y	Neutral	0.422
OPA1	O60313-1.3	Y841A	Pathogenic	0.994
OPA1	O60313-1.3	Y841C	Pathogenic	0.997
OPA1	O60313-1.3	Y841D	Pathogenic	0.995
OPA1	O60313-1.3	Y841E	Pathogenic	0.989
OPA1	O60313-1.3	Y841F	Neutral	0.488
OPA1	O60313-1.3	Y841G	Pathogenic	0.997
OPA1	O60313-1.3	Y841H	Pathogenic	0.722
OPA1	O60313-1.3	Y841I	Pathogenic	0.985
OPA1	O60313-1.3	Y841K	Pathogenic	0.986
OPA1	O60313-1.3	Y841L	Pathogenic	0.986
OPA1	O60313-1.3	Y841M	Pathogenic	0.991
OPA1	O60313-1.3	Y841N	Pathogenic	0.989
OPA1	O60313-1.3	Y841P	Pathogenic	0.999
OPA1	O60313-1.3	Y841Q	Pathogenic	0.978
OPA1	O60313-1.3	Y841R	Pathogenic	0.986
OPA1	O60313-1.3	Y841S	Pathogenic	0.993
OPA1	O60313-1.3	Y841T	Pathogenic	0.995
OPA1	O60313-1.3	Y841V	Pathogenic	0.99
OPA1	O60313-1.3	Y841W	Pathogenic	0.631
OPA1	O60313-1.3	R842A	Pathogenic	0.976
OPA1	O60313-1.3	R842C	Pathogenic	0.995
OPA1	O60313-1.3	R842D	Pathogenic	0.997
OPA1	O60313-1.3	R842E	Pathogenic	0.975
OPA1	O60313-1.3	R842F	Pathogenic	0.991
OPA1	O60313-1.3	R842G	Pathogenic	0.993
OPA1	O60313-1.3	R842H	Pathogenic	0.952
OPA1	O60313-1.3	R842I	Pathogenic	0.991
OPA1	O60313-1.3	R842K	Pathogenic	0.876
OPA1	O60313-1.3	R842L	Pathogenic	0.976
OPA1	O60313-1.3	R842M	Pathogenic	0.956
OPA1	O60313-1.3	R842N	Pathogenic	0.973
OPA1	O60313-1.3	R842P	Pathogenic	0.989
OPA1	O60313-1.3	R842Q	Pathogenic	0.904
OPA1	O60313-1.3	R842S	Pathogenic	0.983
OPA1	O60313-1.3	R842T	Pathogenic	0.979
OPA1	O60313-1.3	R842V	Pathogenic	0.994
OPA1	O60313-1.3	R842W	Pathogenic	0.987
OPA1	O60313-1.3	R842Y	Pathogenic	0.988
OPA1	O60313-1.3	R843A	Pathogenic	0.916
OPA1	O60313-1.3	R843C	Pathogenic	0.982
OPA1	O60313-1.3	R843D	Pathogenic	0.989
OPA1	O60313-1.3	R843E	Pathogenic	0.913
OPA1	O60313-1.3	R843F	Pathogenic	0.968
OPA1	O60313-1.3	R843G	Pathogenic	0.975
OPA1	O60313-1.3	R843H	Pathogenic	0.843
OPA1	O60313-1.3	R843I	Pathogenic	0.967
OPA1	O60313-1.3	R843K	Pathogenic	0.656
OPA1	O60313-1.3	R843L	Pathogenic	0.917
OPA1	O60313-1.3	R843M	Pathogenic	0.854
OPA1	O60313-1.3	R843N	Pathogenic	0.906
OPA1	O60313-1.3	R843P	Pathogenic	0.96
OPA1	O60313-1.3	R843Q	Pathogenic	0.716
OPA1	O60313-1.3	R843S	Pathogenic	0.939
OPA1	O60313-1.3	R843T	Pathogenic	0.927
OPA1	O60313-1.3	R843V	Pathogenic	0.979
OPA1	O60313-1.3	R843W	Pathogenic	0.952
OPA1	O60313-1.3	R843Y	Pathogenic	0.958
OPA1	O60313-1.3	H844A	Pathogenic	0.824
OPA1	O60313-1.3	H844C	Pathogenic	0.887
OPA1	O60313-1.3	H844D	Neutral	0.476
OPA1	O60313-1.3	H844E	Neutral	0.274
OPA1	O60313-1.3	H844F	Neutral	0.32
OPA1	O60313-1.3	H844G	Pathogenic	0.819
OPA1	O60313-1.3	H844I	Pathogenic	0.803
OPA1	O60313-1.3	H844K	Neutral	0.435
OPA1	O60313-1.3	H844L	Pathogenic	0.817
OPA1	O60313-1.3	H844M	Pathogenic	0.703
OPA1	O60313-1.3	H844N	Neutral	0.114
OPA1	O60313-1.3	H844P	Pathogenic	0.778
OPA1	O60313-1.3	H844Q	Neutral	0.361
OPA1	O60313-1.3	H844R	Neutral	0.2
OPA1	O60313-1.3	H844S	Pathogenic	0.624
OPA1	O60313-1.3	H844T	Pathogenic	0.844
OPA1	O60313-1.3	H844V	Pathogenic	0.872
OPA1	O60313-1.3	H844W	Neutral	0.447
OPA1	O60313-1.3	H844Y	Neutral	0.039
OPA1	O60313-1.3	F845A	Pathogenic	0.993
OPA1	O60313-1.3	F845C	Pathogenic	0.996
OPA1	O60313-1.3	F845D	Pathogenic	0.994
OPA1	O60313-1.3	F845E	Pathogenic	0.995
OPA1	O60313-1.3	F845G	Pathogenic	0.996
OPA1	O60313-1.3	F845H	Pathogenic	0.98
OPA1	O60313-1.3	F845I	Pathogenic	0.987
OPA1	O60313-1.3	F845K	Pathogenic	0.994
OPA1	O60313-1.3	F845L	Pathogenic	0.986
OPA1	O60313-1.3	F845M	Pathogenic	0.979
OPA1	O60313-1.3	F845N	Pathogenic	0.995
OPA1	O60313-1.3	F845P	Pathogenic	0.999
OPA1	O60313-1.3	F845Q	Pathogenic	0.997
OPA1	O60313-1.3	F845R	Pathogenic	0.993
OPA1	O60313-1.3	F845S	Pathogenic	0.99
OPA1	O60313-1.3	F845T	Pathogenic	0.993
OPA1	O60313-1.3	F845V	Pathogenic	0.992
OPA1	O60313-1.3	F845W	Pathogenic	0.944
OPA1	O60313-1.3	F845Y	Pathogenic	0.608
OPA1	O60313-1.3	L846A	Pathogenic	0.971
OPA1	O60313-1.3	L846C	Pathogenic	0.985
OPA1	O60313-1.3	L846D	Pathogenic	0.997
OPA1	O60313-1.3	L846E	Pathogenic	0.993
OPA1	O60313-1.3	L846F	Pathogenic	0.979
OPA1	O60313-1.3	L846G	Pathogenic	0.998
OPA1	O60313-1.3	L846H	Pathogenic	0.997
OPA1	O60313-1.3	L846I	Pathogenic	0.849
OPA1	O60313-1.3	L846K	Pathogenic	0.973
OPA1	O60313-1.3	L846M	Pathogenic	0.801
OPA1	O60313-1.3	L846N	Pathogenic	0.993
OPA1	O60313-1.3	L846P	Pathogenic	0.998
OPA1	O60313-1.3	L846Q	Pathogenic	0.986
OPA1	O60313-1.3	L846R	Pathogenic	0.971
OPA1	O60313-1.3	L846S	Pathogenic	0.987
OPA1	O60313-1.3	L846T	Pathogenic	0.973
OPA1	O60313-1.3	L846V	Pathogenic	0.915
OPA1	O60313-1.3	L846W	Pathogenic	0.996
OPA1	O60313-1.3	L846Y	Pathogenic	0.986
OPA1	O60313-1.3	K847A	Neutral	0.2
OPA1	O60313-1.3	K847C	Pathogenic	0.549
OPA1	O60313-1.3	K847D	Neutral	0.424
OPA1	O60313-1.3	K847E	Neutral	0.077
OPA1	O60313-1.3	K847F	Neutral	0.412
OPA1	O60313-1.3	K847G	Neutral	0.473
OPA1	O60313-1.3	K847H	Neutral	0.263
OPA1	O60313-1.3	K847I	Neutral	0.399
OPA1	O60313-1.3	K847L	Neutral	0.201
OPA1	O60313-1.3	K847M	Neutral	0.117
OPA1	O60313-1.3	K847N	Neutral	0.181
OPA1	O60313-1.3	K847P	Neutral	0.158
OPA1	O60313-1.3	K847Q	Neutral	0.054
OPA1	O60313-1.3	K847R	Neutral	0.039
OPA1	O60313-1.3	K847S	Neutral	0.108
OPA1	O60313-1.3	K847T	Neutral	0.224
OPA1	O60313-1.3	K847V	Neutral	0.267
OPA1	O60313-1.3	K847W	Neutral	0.292
OPA1	O60313-1.3	K847Y	Neutral	0.335
OPA1	O60313-1.3	T848A	Neutral	0.045
OPA1	O60313-1.3	T848C	Neutral	0.073
OPA1	O60313-1.3	T848D	Neutral	0.057
OPA1	O60313-1.3	T848E	Neutral	0.061
OPA1	O60313-1.3	T848F	Neutral	0.087
OPA1	O60313-1.3	T848G	Neutral	0.233
OPA1	O60313-1.3	T848H	Neutral	0.27
OPA1	O60313-1.3	T848I	Neutral	0.033
OPA1	O60313-1.3	T848K	Neutral	0.041
OPA1	O60313-1.3	T848L	Neutral	0.036
OPA1	O60313-1.3	T848M	Neutral	0.054
OPA1	O60313-1.3	T848N	Neutral	0.024
OPA1	O60313-1.3	T848P	Neutral	0.092
OPA1	O60313-1.3	T848Q	Neutral	0.086
OPA1	O60313-1.3	T848R	Neutral	0.039
OPA1	O60313-1.3	T848S	Neutral	0.013
OPA1	O60313-1.3	T848V	Neutral	0.021
OPA1	O60313-1.3	T848W	Neutral	0.053
OPA1	O60313-1.3	T848Y	Neutral	0.166
OPA1	O60313-1.3	A849C	Pathogenic	0.736
OPA1	O60313-1.3	A849D	Pathogenic	0.941
OPA1	O60313-1.3	A849E	Pathogenic	0.852
OPA1	O60313-1.3	A849F	Pathogenic	0.903
OPA1	O60313-1.3	A849G	Pathogenic	0.796
OPA1	O60313-1.3	A849H	Pathogenic	0.97
OPA1	O60313-1.3	A849I	Pathogenic	0.768
OPA1	O60313-1.3	A849K	Pathogenic	0.792
OPA1	O60313-1.3	A849L	Pathogenic	0.784
OPA1	O60313-1.3	A849M	Pathogenic	0.848
OPA1	O60313-1.3	A849N	Pathogenic	0.948
OPA1	O60313-1.3	A849P	Pathogenic	0.91
OPA1	O60313-1.3	A849Q	Pathogenic	0.893
OPA1	O60313-1.3	A849R	Pathogenic	0.781
OPA1	O60313-1.3	A849S	Pathogenic	0.577
OPA1	O60313-1.3	A849T	Pathogenic	0.827
OPA1	O60313-1.3	A849V	Pathogenic	0.677
OPA1	O60313-1.3	A849W	Pathogenic	0.941
OPA1	O60313-1.3	A849Y	Pathogenic	0.951
OPA1	O60313-1.3	L850A	Pathogenic	0.971
OPA1	O60313-1.3	L850C	Pathogenic	0.985
OPA1	O60313-1.3	L850D	Pathogenic	0.997
OPA1	O60313-1.3	L850E	Pathogenic	0.993
OPA1	O60313-1.3	L850F	Pathogenic	0.979
OPA1	O60313-1.3	L850G	Pathogenic	0.998
OPA1	O60313-1.3	L850H	Pathogenic	0.997
OPA1	O60313-1.3	L850I	Pathogenic	0.849
OPA1	O60313-1.3	L850K	Pathogenic	0.973
OPA1	O60313-1.3	L850M	Pathogenic	0.801
OPA1	O60313-1.3	L850N	Pathogenic	0.993
OPA1	O60313-1.3	L850P	Pathogenic	0.998
OPA1	O60313-1.3	L850Q	Pathogenic	0.986
OPA1	O60313-1.3	L850R	Pathogenic	0.971
OPA1	O60313-1.3	L850S	Pathogenic	0.987
OPA1	O60313-1.3	L850T	Pathogenic	0.973
OPA1	O60313-1.3	L850V	Pathogenic	0.915
OPA1	O60313-1.3	L850W	Pathogenic	0.996
OPA1	O60313-1.3	L850Y	Pathogenic	0.986
OPA1	O60313-1.3	N851A	Neutral	0.106
OPA1	O60313-1.3	N851C	Neutral	0.165
OPA1	O60313-1.3	N851D	Neutral	0.01
OPA1	O60313-1.3	N851E	Neutral	0.032
OPA1	O60313-1.3	N851F	Neutral	0.078
OPA1	O60313-1.3	N851G	Neutral	0.017
OPA1	O60313-1.3	N851H	Neutral	0.006
OPA1	O60313-1.3	N851I	Neutral	0.08
OPA1	O60313-1.3	N851K	Neutral	0.021
OPA1	O60313-1.3	N851L	Neutral	0.088
OPA1	O60313-1.3	N851M	Neutral	0.048
OPA1	O60313-1.3	N851P	Neutral	0.081
OPA1	O60313-1.3	N851Q	Neutral	0.023
OPA1	O60313-1.3	N851R	Neutral	0.02
OPA1	O60313-1.3	N851S	Neutral	0.007
OPA1	O60313-1.3	N851T	Neutral	0.016
OPA1	O60313-1.3	N851V	Neutral	0.138
OPA1	O60313-1.3	N851W	Neutral	0.127
OPA1	O60313-1.3	N851Y	Neutral	0.058
OPA1	O60313-1.3	H852A	Pathogenic	0.959
OPA1	O60313-1.3	H852C	Pathogenic	0.975
OPA1	O60313-1.3	H852D	Pathogenic	0.818
OPA1	O60313-1.3	H852E	Pathogenic	0.652
OPA1	O60313-1.3	H852F	Pathogenic	0.7
OPA1	O60313-1.3	H852G	Pathogenic	0.957
OPA1	O60313-1.3	H852I	Pathogenic	0.953
OPA1	O60313-1.3	H852K	Pathogenic	0.792
OPA1	O60313-1.3	H852L	Pathogenic	0.957
OPA1	O60313-1.3	H852M	Pathogenic	0.922
OPA1	O60313-1.3	H852N	Neutral	0.389
OPA1	O60313-1.3	H852P	Pathogenic	0.945
OPA1	O60313-1.3	H852Q	Pathogenic	0.736
OPA1	O60313-1.3	H852R	Pathogenic	0.553
OPA1	O60313-1.3	H852S	Pathogenic	0.892
OPA1	O60313-1.3	H852T	Pathogenic	0.964
OPA1	O60313-1.3	H852V	Pathogenic	0.971
OPA1	O60313-1.3	H852W	Pathogenic	0.8
OPA1	O60313-1.3	H852Y	Neutral	0.167
OPA1	O60313-1.3	C853A	Pathogenic	0.823
OPA1	O60313-1.3	C853D	Pathogenic	0.978
OPA1	O60313-1.3	C853E	Pathogenic	0.993
OPA1	O60313-1.3	C853F	Pathogenic	0.969
OPA1	O60313-1.3	C853G	Pathogenic	0.988
OPA1	O60313-1.3	C853H	Pathogenic	0.989
OPA1	O60313-1.3	C853I	Pathogenic	0.917
OPA1	O60313-1.3	C853K	Pathogenic	0.969
OPA1	O60313-1.3	C853L	Pathogenic	0.924
OPA1	O60313-1.3	C853M	Pathogenic	0.949
OPA1	O60313-1.3	C853N	Pathogenic	0.981
OPA1	O60313-1.3	C853P	Pathogenic	0.994
OPA1	O60313-1.3	C853Q	Pathogenic	0.985
OPA1	O60313-1.3	C853R	Pathogenic	0.967
OPA1	O60313-1.3	C853S	Pathogenic	0.91
OPA1	O60313-1.3	C853T	Pathogenic	0.931
OPA1	O60313-1.3	C853V	Pathogenic	0.953
OPA1	O60313-1.3	C853W	Pathogenic	0.948
OPA1	O60313-1.3	C853Y	Pathogenic	0.984
OPA1	O60313-1.3	N854A	Pathogenic	0.939
OPA1	O60313-1.3	N854C	Pathogenic	0.963
OPA1	O60313-1.3	N854D	Pathogenic	0.577
OPA1	O60313-1.3	N854E	Pathogenic	0.813
OPA1	O60313-1.3	N854F	Pathogenic	0.918
OPA1	O60313-1.3	N854G	Pathogenic	0.694
OPA1	O60313-1.3	N854H	Neutral	0.433
OPA1	O60313-1.3	N854I	Pathogenic	0.92
OPA1	O60313-1.3	N854K	Pathogenic	0.74
OPA1	O60313-1.3	N854L	Pathogenic	0.926
OPA1	O60313-1.3	N854M	Pathogenic	0.869
OPA1	O60313-1.3	N854P	Pathogenic	0.92
OPA1	O60313-1.3	N854Q	Pathogenic	0.756
OPA1	O60313-1.3	N854R	Pathogenic	0.728
OPA1	O60313-1.3	N854S	Neutral	0.471
OPA1	O60313-1.3	N854T	Pathogenic	0.68
OPA1	O60313-1.3	N854V	Pathogenic	0.955
OPA1	O60313-1.3	N854W	Pathogenic	0.95
OPA1	O60313-1.3	N854Y	Pathogenic	0.889
OPA1	O60313-1.3	L855A	Pathogenic	0.593
OPA1	O60313-1.3	L855C	Pathogenic	0.744
OPA1	O60313-1.3	L855D	Pathogenic	0.935
OPA1	O60313-1.3	L855E	Pathogenic	0.858
OPA1	O60313-1.3	L855F	Pathogenic	0.663
OPA1	O60313-1.3	L855G	Pathogenic	0.961
OPA1	O60313-1.3	L855H	Pathogenic	0.927
OPA1	O60313-1.3	L855I	Neutral	0.194
OPA1	O60313-1.3	L855K	Pathogenic	0.605
OPA1	O60313-1.3	L855M	Neutral	0.147
OPA1	O60313-1.3	L855N	Pathogenic	0.856
OPA1	O60313-1.3	L855P	Pathogenic	0.951
OPA1	O60313-1.3	L855Q	Pathogenic	0.756
OPA1	O60313-1.3	L855R	Pathogenic	0.59
OPA1	O60313-1.3	L855S	Pathogenic	0.759
OPA1	O60313-1.3	L855T	Pathogenic	0.605
OPA1	O60313-1.3	L855V	Neutral	0.315
OPA1	O60313-1.3	L855W	Pathogenic	0.907
OPA1	O60313-1.3	L855Y	Pathogenic	0.754
OPA1	O60313-1.3	C856A	Pathogenic	0.986
OPA1	O60313-1.3	C856D	Pathogenic	0.998
OPA1	O60313-1.3	C856E	Pathogenic	1.0
OPA1	O60313-1.3	C856F	Pathogenic	0.998
OPA1	O60313-1.3	C856G	Pathogenic	0.999
OPA1	O60313-1.3	C856H	Pathogenic	0.999
OPA1	O60313-1.3	C856I	Pathogenic	0.994
OPA1	O60313-1.3	C856K	Pathogenic	0.998
OPA1	O60313-1.3	C856L	Pathogenic	0.994
OPA1	O60313-1.3	C856M	Pathogenic	0.996
OPA1	O60313-1.3	C856N	Pathogenic	0.999
OPA1	O60313-1.3	C856P	Pathogenic	1.0
OPA1	O60313-1.3	C856Q	Pathogenic	0.999
OPA1	O60313-1.3	C856R	Pathogenic	0.998
OPA1	O60313-1.3	C856S	Pathogenic	0.993
OPA1	O60313-1.3	C856T	Pathogenic	0.995
OPA1	O60313-1.3	C856V	Pathogenic	0.997
OPA1	O60313-1.3	C856W	Pathogenic	0.996
OPA1	O60313-1.3	C856Y	Pathogenic	0.999
OPA1	O60313-1.3	R857A	Pathogenic	0.748
OPA1	O60313-1.3	R857C	Pathogenic	0.935
OPA1	O60313-1.3	R857D	Pathogenic	0.962
OPA1	O60313-1.3	R857E	Pathogenic	0.74
OPA1	O60313-1.3	R857F	Pathogenic	0.893
OPA1	O60313-1.3	R857G	Pathogenic	0.914
OPA1	O60313-1.3	R857H	Pathogenic	0.593
OPA1	O60313-1.3	R857I	Pathogenic	0.887
OPA1	O60313-1.3	R857K	Neutral	0.34
OPA1	O60313-1.3	R857L	Pathogenic	0.749
OPA1	O60313-1.3	R857M	Pathogenic	0.612
OPA1	O60313-1.3	R857N	Pathogenic	0.724
OPA1	O60313-1.3	R857P	Pathogenic	0.866
OPA1	O60313-1.3	R857Q	Neutral	0.406
OPA1	O60313-1.3	R857S	Pathogenic	0.806
OPA1	O60313-1.3	R857T	Pathogenic	0.774
OPA1	O60313-1.3	R857V	Pathogenic	0.926
OPA1	O60313-1.3	R857W	Pathogenic	0.844
OPA1	O60313-1.3	R857Y	Pathogenic	0.862
OPA1	O60313-1.3	R858A	Pathogenic	0.734
OPA1	O60313-1.3	R858C	Pathogenic	0.931
OPA1	O60313-1.3	R858D	Pathogenic	0.959
OPA1	O60313-1.3	R858E	Pathogenic	0.725
OPA1	O60313-1.3	R858F	Pathogenic	0.885
OPA1	O60313-1.3	R858G	Pathogenic	0.908
OPA1	O60313-1.3	R858H	Pathogenic	0.574
OPA1	O60313-1.3	R858I	Pathogenic	0.879
OPA1	O60313-1.3	R858K	Neutral	0.323
OPA1	O60313-1.3	R858L	Pathogenic	0.734
OPA1	O60313-1.3	R858M	Pathogenic	0.594
OPA1	O60313-1.3	R858N	Pathogenic	0.709
OPA1	O60313-1.3	R858P	Pathogenic	0.857
OPA1	O60313-1.3	R858Q	Neutral	0.388
OPA1	O60313-1.3	R858S	Pathogenic	0.794
OPA1	O60313-1.3	R858T	Pathogenic	0.761
OPA1	O60313-1.3	R858V	Pathogenic	0.921
OPA1	O60313-1.3	R858W	Pathogenic	0.833
OPA1	O60313-1.3	R858Y	Pathogenic	0.853
OPA1	O60313-1.3	G859A	Pathogenic	0.958
OPA1	O60313-1.3	G859C	Pathogenic	0.996
OPA1	O60313-1.3	G859D	Pathogenic	0.976
OPA1	O60313-1.3	G859E	Pathogenic	0.992
OPA1	O60313-1.3	G859F	Pathogenic	0.991
OPA1	O60313-1.3	G859H	Pathogenic	0.995
OPA1	O60313-1.3	G859I	Pathogenic	0.997
OPA1	O60313-1.3	G859K	Pathogenic	0.988
OPA1	O60313-1.3	G859L	Pathogenic	0.997
OPA1	O60313-1.3	G859M	Pathogenic	0.995
OPA1	O60313-1.3	G859N	Pathogenic	0.94
OPA1	O60313-1.3	G859P	Pathogenic	0.992
OPA1	O60313-1.3	G859Q	Pathogenic	0.994
OPA1	O60313-1.3	G859R	Pathogenic	0.987
OPA1	O60313-1.3	G859S	Pathogenic	0.966
OPA1	O60313-1.3	G859T	Pathogenic	0.995
OPA1	O60313-1.3	G859V	Pathogenic	0.995
OPA1	O60313-1.3	G859W	Pathogenic	0.958
OPA1	O60313-1.3	G859Y	Pathogenic	0.996
OPA1	O60313-1.3	F860A	Pathogenic	0.903
OPA1	O60313-1.3	F860C	Pathogenic	0.949
OPA1	O60313-1.3	F860D	Pathogenic	0.917
OPA1	O60313-1.3	F860E	Pathogenic	0.93
OPA1	O60313-1.3	F860G	Pathogenic	0.95
OPA1	O60313-1.3	F860H	Pathogenic	0.769
OPA1	O60313-1.3	F860I	Pathogenic	0.84
OPA1	O60313-1.3	F860K	Pathogenic	0.914
OPA1	O60313-1.3	F860L	Pathogenic	0.831
OPA1	O60313-1.3	F860M	Pathogenic	0.762
OPA1	O60313-1.3	F860N	Pathogenic	0.929
OPA1	O60313-1.3	F860P	Pathogenic	0.992
OPA1	O60313-1.3	F860Q	Pathogenic	0.952
OPA1	O60313-1.3	F860R	Pathogenic	0.909
OPA1	O60313-1.3	F860S	Pathogenic	0.875
OPA1	O60313-1.3	F860T	Pathogenic	0.908
OPA1	O60313-1.3	F860V	Pathogenic	0.895
OPA1	O60313-1.3	F860W	Pathogenic	0.531
OPA1	O60313-1.3	F860Y	Neutral	0.095
OPA1	O60313-1.3	Y861A	Pathogenic	0.997
OPA1	O60313-1.3	Y861C	Pathogenic	0.998
OPA1	O60313-1.3	Y861D	Pathogenic	0.997
OPA1	O60313-1.3	Y861E	Pathogenic	0.993
OPA1	O60313-1.3	Y861F	Pathogenic	0.615
OPA1	O60313-1.3	Y861G	Pathogenic	0.998
OPA1	O60313-1.3	Y861H	Pathogenic	0.813
OPA1	O60313-1.3	Y861I	Pathogenic	0.991
OPA1	O60313-1.3	Y861K	Pathogenic	0.992
OPA1	O60313-1.3	Y861L	Pathogenic	0.992
OPA1	O60313-1.3	Y861M	Pathogenic	0.994
OPA1	O60313-1.3	Y861N	Pathogenic	0.993
OPA1	O60313-1.3	Y861P	Pathogenic	0.999
OPA1	O60313-1.3	Y861Q	Pathogenic	0.987
OPA1	O60313-1.3	Y861R	Pathogenic	0.991
OPA1	O60313-1.3	Y861S	Pathogenic	0.996
OPA1	O60313-1.3	Y861T	Pathogenic	0.997
OPA1	O60313-1.3	Y861V	Pathogenic	0.994
OPA1	O60313-1.3	Y861W	Pathogenic	0.741
OPA1	O60313-1.3	Y862A	Pathogenic	0.955
OPA1	O60313-1.3	Y862C	Pathogenic	0.976
OPA1	O60313-1.3	Y862D	Pathogenic	0.962
OPA1	O60313-1.3	Y862E	Pathogenic	0.912
OPA1	O60313-1.3	Y862F	Neutral	0.102
OPA1	O60313-1.3	Y862G	Pathogenic	0.977
OPA1	O60313-1.3	Y862H	Neutral	0.236
OPA1	O60313-1.3	Y862I	Pathogenic	0.883
OPA1	O60313-1.3	Y862K	Pathogenic	0.893
OPA1	O60313-1.3	Y862L	Pathogenic	0.893
OPA1	O60313-1.3	Y862M	Pathogenic	0.927
OPA1	O60313-1.3	Y862N	Pathogenic	0.911
OPA1	O60313-1.3	Y862P	Pathogenic	0.99
OPA1	O60313-1.3	Y862Q	Pathogenic	0.843
OPA1	O60313-1.3	Y862R	Pathogenic	0.891
OPA1	O60313-1.3	Y862S	Pathogenic	0.94
OPA1	O60313-1.3	Y862T	Pathogenic	0.957
OPA1	O60313-1.3	Y862V	Pathogenic	0.923
OPA1	O60313-1.3	Y862W	Neutral	0.168
OPA1	O60313-1.3	Y863A	Pathogenic	0.997
OPA1	O60313-1.3	Y863C	Pathogenic	0.998
OPA1	O60313-1.3	Y863D	Pathogenic	0.997
OPA1	O60313-1.3	Y863E	Pathogenic	0.994
OPA1	O60313-1.3	Y863F	Pathogenic	0.637
OPA1	O60313-1.3	Y863G	Pathogenic	0.999
OPA1	O60313-1.3	Y863H	Pathogenic	0.827
OPA1	O60313-1.3	Y863I	Pathogenic	0.992
OPA1	O60313-1.3	Y863K	Pathogenic	0.992
OPA1	O60313-1.3	Y863L	Pathogenic	0.992
OPA1	O60313-1.3	Y863M	Pathogenic	0.995
OPA1	O60313-1.3	Y863N	Pathogenic	0.994
OPA1	O60313-1.3	Y863P	Pathogenic	0.999
OPA1	O60313-1.3	Y863Q	Pathogenic	0.988
OPA1	O60313-1.3	Y863R	Pathogenic	0.992
OPA1	O60313-1.3	Y863S	Pathogenic	0.996
OPA1	O60313-1.3	Y863T	Pathogenic	0.997
OPA1	O60313-1.3	Y863V	Pathogenic	0.995
OPA1	O60313-1.3	Y863W	Pathogenic	0.758
OPA1	O60313-1.3	Q864A	Pathogenic	0.808
OPA1	O60313-1.3	Q864C	Pathogenic	0.953
OPA1	O60313-1.3	Q864D	Pathogenic	0.609
OPA1	O60313-1.3	Q864E	Neutral	0.182
OPA1	O60313-1.3	Q864F	Pathogenic	0.909
OPA1	O60313-1.3	Q864G	Pathogenic	0.938
OPA1	O60313-1.3	Q864H	Pathogenic	0.667
OPA1	O60313-1.3	Q864I	Pathogenic	0.912
OPA1	O60313-1.3	Q864K	Neutral	0.306
OPA1	O60313-1.3	Q864L	Pathogenic	0.796
OPA1	O60313-1.3	Q864M	Neutral	0.417
OPA1	O60313-1.3	Q864N	Pathogenic	0.649
OPA1	O60313-1.3	Q864P	Pathogenic	0.759
OPA1	O60313-1.3	Q864R	Neutral	0.293
OPA1	O60313-1.3	Q864S	Pathogenic	0.67
OPA1	O60313-1.3	Q864T	Pathogenic	0.829
OPA1	O60313-1.3	Q864V	Pathogenic	0.859
OPA1	O60313-1.3	Q864W	Pathogenic	0.671
OPA1	O60313-1.3	Q864Y	Pathogenic	0.714
OPA1	O60313-1.3	R865A	Neutral	0.47
OPA1	O60313-1.3	R865C	Pathogenic	0.812
OPA1	O60313-1.3	R865D	Pathogenic	0.883
OPA1	O60313-1.3	R865E	Neutral	0.46
OPA1	O60313-1.3	R865F	Pathogenic	0.712
OPA1	O60313-1.3	R865G	Pathogenic	0.76
OPA1	O60313-1.3	R865H	Neutral	0.303
OPA1	O60313-1.3	R865I	Pathogenic	0.701
OPA1	O60313-1.3	R865K	Neutral	0.133
OPA1	O60313-1.3	R865L	Neutral	0.471
OPA1	O60313-1.3	R865M	Neutral	0.32
OPA1	O60313-1.3	R865N	Neutral	0.439
OPA1	O60313-1.3	R865P	Pathogenic	0.658
OPA1	O60313-1.3	R865Q	Neutral	0.169
OPA1	O60313-1.3	R865S	Pathogenic	0.554
OPA1	O60313-1.3	R865T	Pathogenic	0.506
OPA1	O60313-1.3	R865V	Pathogenic	0.789
OPA1	O60313-1.3	R865W	Pathogenic	0.617
OPA1	O60313-1.3	R865Y	Pathogenic	0.651
OPA1	O60313-1.3	H866A	Pathogenic	0.933
OPA1	O60313-1.3	H866C	Pathogenic	0.959
OPA1	O60313-1.3	H866D	Pathogenic	0.729
OPA1	O60313-1.3	H866E	Pathogenic	0.528
OPA1	O60313-1.3	H866F	Pathogenic	0.583
OPA1	O60313-1.3	H866G	Pathogenic	0.931
OPA1	O60313-1.3	H866I	Pathogenic	0.924
OPA1	O60313-1.3	H866K	Pathogenic	0.695
OPA1	O60313-1.3	H866L	Pathogenic	0.93
OPA1	O60313-1.3	H866M	Pathogenic	0.875
OPA1	O60313-1.3	H866N	Neutral	0.275
OPA1	O60313-1.3	H866P	Pathogenic	0.912
OPA1	O60313-1.3	H866Q	Pathogenic	0.626
OPA1	O60313-1.3	H866R	Neutral	0.425
OPA1	O60313-1.3	H866S	Pathogenic	0.831
OPA1	O60313-1.3	H866T	Pathogenic	0.941
OPA1	O60313-1.3	H866V	Pathogenic	0.953
OPA1	O60313-1.3	H866W	Pathogenic	0.705
OPA1	O60313-1.3	H866Y	Neutral	0.107
OPA1	O60313-1.3	F867A	Pathogenic	0.788
OPA1	O60313-1.3	F867C	Pathogenic	0.881
OPA1	O60313-1.3	F867D	Pathogenic	0.815
OPA1	O60313-1.3	F867E	Pathogenic	0.841
OPA1	O60313-1.3	F867G	Pathogenic	0.883
OPA1	O60313-1.3	F867H	Pathogenic	0.569
OPA1	O60313-1.3	F867I	Pathogenic	0.677
OPA1	O60313-1.3	F867K	Pathogenic	0.809
OPA1	O60313-1.3	F867L	Pathogenic	0.662
OPA1	O60313-1.3	F867M	Pathogenic	0.56
OPA1	O60313-1.3	F867N	Pathogenic	0.839
OPA1	O60313-1.3	F867P	Pathogenic	0.98
OPA1	O60313-1.3	F867Q	Pathogenic	0.888
OPA1	O60313-1.3	F867R	Pathogenic	0.799
OPA1	O60313-1.3	F867S	Pathogenic	0.735
OPA1	O60313-1.3	F867T	Pathogenic	0.796
OPA1	O60313-1.3	F867V	Pathogenic	0.773
OPA1	O60313-1.3	F867W	Neutral	0.311
OPA1	O60313-1.3	F867Y	Neutral	0.04
OPA1	O60313-1.3	V868A	Neutral	0.138
OPA1	O60313-1.3	V868C	Neutral	0.48
OPA1	O60313-1.3	V868D	Pathogenic	0.614
OPA1	O60313-1.3	V868E	Neutral	0.391
OPA1	O60313-1.3	V868F	Neutral	0.394
OPA1	O60313-1.3	V868G	Pathogenic	0.733
OPA1	O60313-1.3	V868H	Pathogenic	0.785
OPA1	O60313-1.3	V868I	Neutral	0.009
OPA1	O60313-1.3	V868K	Neutral	0.297
OPA1	O60313-1.3	V868L	Neutral	0.08
OPA1	O60313-1.3	V868M	Neutral	0.118
OPA1	O60313-1.3	V868N	Pathogenic	0.654
OPA1	O60313-1.3	V868P	Pathogenic	0.681
OPA1	O60313-1.3	V868Q	Neutral	0.48
OPA1	O60313-1.3	V868R	Pathogenic	0.535
OPA1	O60313-1.3	V868S	Pathogenic	0.501
OPA1	O60313-1.3	V868T	Neutral	0.144
OPA1	O60313-1.3	V868W	Pathogenic	0.764
OPA1	O60313-1.3	V868Y	Neutral	0.459
OPA1	O60313-1.3	D869A	Pathogenic	0.946
OPA1	O60313-1.3	D869C	Pathogenic	0.967
OPA1	O60313-1.3	D869E	Neutral	0.376
OPA1	O60313-1.3	D869F	Pathogenic	0.924
OPA1	O60313-1.3	D869G	Pathogenic	0.882
OPA1	O60313-1.3	D869H	Pathogenic	0.875
OPA1	O60313-1.3	D869I	Pathogenic	0.926
OPA1	O60313-1.3	D869K	Pathogenic	0.925
OPA1	O60313-1.3	D869L	Pathogenic	0.976
OPA1	O60313-1.3	D869M	Pathogenic	0.955
OPA1	O60313-1.3	D869N	Pathogenic	0.64
OPA1	O60313-1.3	D869P	Pathogenic	0.819
OPA1	O60313-1.3	D869Q	Pathogenic	0.773
OPA1	O60313-1.3	D869R	Pathogenic	0.971
OPA1	O60313-1.3	D869S	Pathogenic	0.745
OPA1	O60313-1.3	D869T	Pathogenic	0.873
OPA1	O60313-1.3	D869V	Pathogenic	0.958
OPA1	O60313-1.3	D869W	Pathogenic	0.954
OPA1	O60313-1.3	D869Y	Pathogenic	0.962
OPA1	O60313-1.3	S870A	Pathogenic	0.514
OPA1	O60313-1.3	S870C	Pathogenic	0.824
OPA1	O60313-1.3	S870D	Pathogenic	0.673
OPA1	O60313-1.3	S870E	Pathogenic	0.684
OPA1	O60313-1.3	S870F	Pathogenic	0.844
OPA1	O60313-1.3	S870G	Pathogenic	0.791
OPA1	O60313-1.3	S870H	Pathogenic	0.9
OPA1	O60313-1.3	S870I	Pathogenic	0.847
OPA1	O60313-1.3	S870K	Pathogenic	0.588
OPA1	O60313-1.3	S870L	Pathogenic	0.859
OPA1	O60313-1.3	S870M	Pathogenic	0.763
OPA1	O60313-1.3	S870N	Neutral	0.448
OPA1	O60313-1.3	S870P	Pathogenic	0.854
OPA1	O60313-1.3	S870Q	Pathogenic	0.757
OPA1	O60313-1.3	S870R	Pathogenic	0.795
OPA1	O60313-1.3	S870T	Pathogenic	0.513
OPA1	O60313-1.3	S870V	Pathogenic	0.911
OPA1	O60313-1.3	S870W	Pathogenic	0.902
OPA1	O60313-1.3	S870Y	Pathogenic	0.918
OPA1	O60313-1.3	E871A	Pathogenic	0.965
OPA1	O60313-1.3	E871C	Pathogenic	0.997
OPA1	O60313-1.3	E871D	Pathogenic	0.723
OPA1	O60313-1.3	E871F	Pathogenic	0.984
OPA1	O60313-1.3	E871G	Pathogenic	0.99
OPA1	O60313-1.3	E871H	Pathogenic	0.927
OPA1	O60313-1.3	E871I	Pathogenic	0.985
OPA1	O60313-1.3	E871K	Pathogenic	0.857
OPA1	O60313-1.3	E871L	Pathogenic	0.986
OPA1	O60313-1.3	E871M	Pathogenic	0.974
OPA1	O60313-1.3	E871N	Pathogenic	0.961
OPA1	O60313-1.3	E871P	Pathogenic	0.954
OPA1	O60313-1.3	E871Q	Pathogenic	0.678
OPA1	O60313-1.3	E871R	Pathogenic	0.942
OPA1	O60313-1.3	E871S	Pathogenic	0.93
OPA1	O60313-1.3	E871T	Pathogenic	0.97
OPA1	O60313-1.3	E871V	Pathogenic	0.976
OPA1	O60313-1.3	E871W	Pathogenic	0.974
OPA1	O60313-1.3	E871Y	Pathogenic	0.979
OPA1	O60313-1.3	L872A	Pathogenic	0.669
OPA1	O60313-1.3	L872C	Pathogenic	0.801
OPA1	O60313-1.3	L872D	Pathogenic	0.953
OPA1	O60313-1.3	L872E	Pathogenic	0.893
OPA1	O60313-1.3	L872F	Pathogenic	0.732
OPA1	O60313-1.3	L872G	Pathogenic	0.972
OPA1	O60313-1.3	L872H	Pathogenic	0.946
OPA1	O60313-1.3	L872I	Neutral	0.251
OPA1	O60313-1.3	L872K	Pathogenic	0.68
OPA1	O60313-1.3	L872M	Neutral	0.193
OPA1	O60313-1.3	L872N	Pathogenic	0.892
OPA1	O60313-1.3	L872P	Pathogenic	0.964
OPA1	O60313-1.3	L872Q	Pathogenic	0.812
OPA1	O60313-1.3	L872R	Pathogenic	0.666
OPA1	O60313-1.3	L872S	Pathogenic	0.814
OPA1	O60313-1.3	L872T	Pathogenic	0.68
OPA1	O60313-1.3	L872V	Neutral	0.389
OPA1	O60313-1.3	L872W	Pathogenic	0.931
OPA1	O60313-1.3	L872Y	Pathogenic	0.81
OPA1	O60313-1.3	E873A	Pathogenic	0.964
OPA1	O60313-1.3	E873C	Pathogenic	0.997
OPA1	O60313-1.3	E873D	Pathogenic	0.715
OPA1	O60313-1.3	E873F	Pathogenic	0.984
OPA1	O60313-1.3	E873G	Pathogenic	0.99
OPA1	O60313-1.3	E873H	Pathogenic	0.924
OPA1	O60313-1.3	E873I	Pathogenic	0.984
OPA1	O60313-1.3	E873K	Pathogenic	0.852
OPA1	O60313-1.3	E873L	Pathogenic	0.986
OPA1	O60313-1.3	E873M	Pathogenic	0.973
OPA1	O60313-1.3	E873N	Pathogenic	0.959
OPA1	O60313-1.3	E873P	Pathogenic	0.952
OPA1	O60313-1.3	E873Q	Pathogenic	0.67
OPA1	O60313-1.3	E873R	Pathogenic	0.94
OPA1	O60313-1.3	E873S	Pathogenic	0.928
OPA1	O60313-1.3	E873T	Pathogenic	0.968
OPA1	O60313-1.3	E873V	Pathogenic	0.975
OPA1	O60313-1.3	E873W	Pathogenic	0.973
OPA1	O60313-1.3	E873Y	Pathogenic	0.978
OPA1	O60313-1.3	C874A	Pathogenic	0.987
OPA1	O60313-1.3	C874D	Pathogenic	0.999
OPA1	O60313-1.3	C874E	Pathogenic	1.0
OPA1	O60313-1.3	C874F	Pathogenic	0.998
OPA1	O60313-1.3	C874G	Pathogenic	0.999
OPA1	O60313-1.3	C874H	Pathogenic	0.999
OPA1	O60313-1.3	C874I	Pathogenic	0.994
OPA1	O60313-1.3	C874K	Pathogenic	0.998
OPA1	O60313-1.3	C874L	Pathogenic	0.995
OPA1	O60313-1.3	C874M	Pathogenic	0.997
OPA1	O60313-1.3	C874N	Pathogenic	0.999
OPA1	O60313-1.3	C874P	Pathogenic	1.0
OPA1	O60313-1.3	C874Q	Pathogenic	0.999
OPA1	O60313-1.3	C874R	Pathogenic	0.998
OPA1	O60313-1.3	C874S	Pathogenic	0.994
OPA1	O60313-1.3	C874T	Pathogenic	0.995
OPA1	O60313-1.3	C874V	Pathogenic	0.997
OPA1	O60313-1.3	C874W	Pathogenic	0.997
OPA1	O60313-1.3	C874Y	Pathogenic	0.999
OPA1	O60313-1.3	N875A	Pathogenic	0.982
OPA1	O60313-1.3	N875C	Pathogenic	0.989
OPA1	O60313-1.3	N875D	Pathogenic	0.83
OPA1	O60313-1.3	N875E	Pathogenic	0.939
OPA1	O60313-1.3	N875F	Pathogenic	0.975
OPA1	O60313-1.3	N875G	Pathogenic	0.89
OPA1	O60313-1.3	N875H	Pathogenic	0.732
OPA1	O60313-1.3	N875I	Pathogenic	0.976
OPA1	O60313-1.3	N875K	Pathogenic	0.911
OPA1	O60313-1.3	N875L	Pathogenic	0.978
OPA1	O60313-1.3	N875M	Pathogenic	0.96
OPA1	O60313-1.3	N875P	Pathogenic	0.976
OPA1	O60313-1.3	N875Q	Pathogenic	0.917
OPA1	O60313-1.3	N875R	Pathogenic	0.906
OPA1	O60313-1.3	N875S	Pathogenic	0.761
OPA1	O60313-1.3	N875T	Pathogenic	0.884
OPA1	O60313-1.3	N875V	Pathogenic	0.987
OPA1	O60313-1.3	N875W	Pathogenic	0.986
OPA1	O60313-1.3	N875Y	Pathogenic	0.966
OPA1	O60313-1.3	D876A	Pathogenic	0.995
OPA1	O60313-1.3	D876C	Pathogenic	0.997
OPA1	O60313-1.3	D876E	Pathogenic	0.875
OPA1	O60313-1.3	D876F	Pathogenic	0.993
OPA1	O60313-1.3	D876G	Pathogenic	0.989
OPA1	O60313-1.3	D876H	Pathogenic	0.988
OPA1	O60313-1.3	D876I	Pathogenic	0.993
OPA1	O60313-1.3	D876K	Pathogenic	0.993
OPA1	O60313-1.3	D876L	Pathogenic	0.998
OPA1	O60313-1.3	D876M	Pathogenic	0.996
OPA1	O60313-1.3	D876N	Pathogenic	0.954
OPA1	O60313-1.3	D876P	Pathogenic	0.981
OPA1	O60313-1.3	D876Q	Pathogenic	0.975
OPA1	O60313-1.3	D876R	Pathogenic	0.997
OPA1	O60313-1.3	D876S	Pathogenic	0.971
OPA1	O60313-1.3	D876T	Pathogenic	0.988
OPA1	O60313-1.3	D876V	Pathogenic	0.996
OPA1	O60313-1.3	D876W	Pathogenic	0.996
OPA1	O60313-1.3	D876Y	Pathogenic	0.997
OPA1	O60313-1.3	V877A	Pathogenic	0.743
OPA1	O60313-1.3	V877C	Pathogenic	0.943
OPA1	O60313-1.3	V877D	Pathogenic	0.966
OPA1	O60313-1.3	V877E	Pathogenic	0.921
OPA1	O60313-1.3	V877F	Pathogenic	0.922
OPA1	O60313-1.3	V877G	Pathogenic	0.98
OPA1	O60313-1.3	V877H	Pathogenic	0.985
OPA1	O60313-1.3	V877I	Neutral	0.146
OPA1	O60313-1.3	V877K	Pathogenic	0.884
OPA1	O60313-1.3	V877L	Pathogenic	0.612
OPA1	O60313-1.3	V877M	Pathogenic	0.708
OPA1	O60313-1.3	V877N	Pathogenic	0.972
OPA1	O60313-1.3	V877P	Pathogenic	0.975
OPA1	O60313-1.3	V877Q	Pathogenic	0.944
OPA1	O60313-1.3	V877R	Pathogenic	0.954
OPA1	O60313-1.3	V877S	Pathogenic	0.948
OPA1	O60313-1.3	V877T	Pathogenic	0.752
OPA1	O60313-1.3	V877W	Pathogenic	0.983
OPA1	O60313-1.3	V877Y	Pathogenic	0.939
OPA1	O60313-1.3	V878A	Pathogenic	0.963
OPA1	O60313-1.3	V878C	Pathogenic	0.993
OPA1	O60313-1.3	V878D	Pathogenic	0.996
OPA1	O60313-1.3	V878E	Pathogenic	0.991
OPA1	O60313-1.3	V878F	Pathogenic	0.991
OPA1	O60313-1.3	V878G	Pathogenic	0.998
OPA1	O60313-1.3	V878H	Pathogenic	0.998
OPA1	O60313-1.3	V878I	Pathogenic	0.606
OPA1	O60313-1.3	V878K	Pathogenic	0.986
OPA1	O60313-1.3	V878L	Pathogenic	0.934
OPA1	O60313-1.3	V878M	Pathogenic	0.956
OPA1	O60313-1.3	V878N	Pathogenic	0.997
OPA1	O60313-1.3	V878P	Pathogenic	0.997
OPA1	O60313-1.3	V878Q	Pathogenic	0.993
OPA1	O60313-1.3	V878R	Pathogenic	0.995
OPA1	O60313-1.3	V878S	Pathogenic	0.994
OPA1	O60313-1.3	V878T	Pathogenic	0.965
OPA1	O60313-1.3	V878W	Pathogenic	0.998
OPA1	O60313-1.3	V878Y	Pathogenic	0.993
OPA1	O60313-1.3	L879A	Pathogenic	0.974
OPA1	O60313-1.3	L879C	Pathogenic	0.987
OPA1	O60313-1.3	L879D	Pathogenic	0.997
OPA1	O60313-1.3	L879E	Pathogenic	0.994
OPA1	O60313-1.3	L879F	Pathogenic	0.98
OPA1	O60313-1.3	L879G	Pathogenic	0.998
OPA1	O60313-1.3	L879H	Pathogenic	0.997
OPA1	O60313-1.3	L879I	Pathogenic	0.859
OPA1	O60313-1.3	L879K	Pathogenic	0.975
OPA1	O60313-1.3	L879M	Pathogenic	0.814
OPA1	O60313-1.3	L879N	Pathogenic	0.993
OPA1	O60313-1.3	L879P	Pathogenic	0.998
OPA1	O60313-1.3	L879Q	Pathogenic	0.987
OPA1	O60313-1.3	L879R	Pathogenic	0.973
OPA1	O60313-1.3	L879S	Pathogenic	0.988
OPA1	O60313-1.3	L879T	Pathogenic	0.975
OPA1	O60313-1.3	L879V	Pathogenic	0.921
OPA1	O60313-1.3	L879W	Pathogenic	0.996
OPA1	O60313-1.3	L879Y	Pathogenic	0.987
OPA1	O60313-1.3	F880A	Pathogenic	0.993
OPA1	O60313-1.3	F880C	Pathogenic	0.997
OPA1	O60313-1.3	F880D	Pathogenic	0.994
OPA1	O60313-1.3	F880E	Pathogenic	0.995
OPA1	O60313-1.3	F880G	Pathogenic	0.997
OPA1	O60313-1.3	F880H	Pathogenic	0.982
OPA1	O60313-1.3	F880I	Pathogenic	0.988
OPA1	O60313-1.3	F880K	Pathogenic	0.994
OPA1	O60313-1.3	F880L	Pathogenic	0.988
OPA1	O60313-1.3	F880M	Pathogenic	0.981
OPA1	O60313-1.3	F880N	Pathogenic	0.995
OPA1	O60313-1.3	F880P	Pathogenic	1.0
OPA1	O60313-1.3	F880Q	Pathogenic	0.997
OPA1	O60313-1.3	F880R	Pathogenic	0.994
OPA1	O60313-1.3	F880S	Pathogenic	0.991
OPA1	O60313-1.3	F880T	Pathogenic	0.994
OPA1	O60313-1.3	F880V	Pathogenic	0.993
OPA1	O60313-1.3	F880W	Pathogenic	0.948
OPA1	O60313-1.3	F880Y	Pathogenic	0.627
OPA1	O60313-1.3	W881A	Pathogenic	0.997
OPA1	O60313-1.3	W881C	Pathogenic	0.996
OPA1	O60313-1.3	W881D	Pathogenic	0.997
OPA1	O60313-1.3	W881E	Pathogenic	0.994
OPA1	O60313-1.3	W881F	Pathogenic	0.959
OPA1	O60313-1.3	W881G	Pathogenic	0.988
OPA1	O60313-1.3	W881H	Pathogenic	0.992
OPA1	O60313-1.3	W881I	Pathogenic	0.999
OPA1	O60313-1.3	W881K	Pathogenic	0.992
OPA1	O60313-1.3	W881L	Pathogenic	0.998
OPA1	O60313-1.3	W881M	Pathogenic	0.991
OPA1	O60313-1.3	W881N	Pathogenic	0.998
OPA1	O60313-1.3	W881P	Pathogenic	0.999
OPA1	O60313-1.3	W881Q	Pathogenic	0.988
OPA1	O60313-1.3	W881R	Pathogenic	0.993
OPA1	O60313-1.3	W881S	Pathogenic	0.996
OPA1	O60313-1.3	W881T	Pathogenic	0.992
OPA1	O60313-1.3	W881V	Pathogenic	0.999
OPA1	O60313-1.3	W881Y	Pathogenic	0.796
OPA1	O60313-1.3	R882A	Pathogenic	0.978
OPA1	O60313-1.3	R882C	Pathogenic	0.995
OPA1	O60313-1.3	R882D	Pathogenic	0.997
OPA1	O60313-1.3	R882E	Pathogenic	0.977
OPA1	O60313-1.3	R882F	Pathogenic	0.992
OPA1	O60313-1.3	R882G	Pathogenic	0.994
OPA1	O60313-1.3	R882H	Pathogenic	0.956
OPA1	O60313-1.3	R882I	Pathogenic	0.992
OPA1	O60313-1.3	R882K	Pathogenic	0.885
OPA1	O60313-1.3	R882L	Pathogenic	0.978
OPA1	O60313-1.3	R882M	Pathogenic	0.959
OPA1	O60313-1.3	R882N	Pathogenic	0.975
OPA1	O60313-1.3	R882P	Pathogenic	0.99
OPA1	O60313-1.3	R882Q	Pathogenic	0.911
OPA1	O60313-1.3	R882S	Pathogenic	0.984
OPA1	O60313-1.3	R882T	Pathogenic	0.981
OPA1	O60313-1.3	R882V	Pathogenic	0.995
OPA1	O60313-1.3	R882W	Pathogenic	0.988
OPA1	O60313-1.3	R882Y	Pathogenic	0.989
OPA1	O60313-1.3	I883A	Pathogenic	0.955
OPA1	O60313-1.3	I883C	Pathogenic	0.977
OPA1	O60313-1.3	I883D	Pathogenic	0.986
OPA1	O60313-1.3	I883E	Pathogenic	0.989
OPA1	O60313-1.3	I883F	Pathogenic	0.971
OPA1	O60313-1.3	I883G	Pathogenic	0.997
OPA1	O60313-1.3	I883H	Pathogenic	0.995
OPA1	O60313-1.3	I883K	Pathogenic	0.985
OPA1	O60313-1.3	I883L	Pathogenic	0.794
OPA1	O60313-1.3	I883M	Pathogenic	0.879
OPA1	O60313-1.3	I883N	Pathogenic	0.989
OPA1	O60313-1.3	I883P	Pathogenic	0.996
OPA1	O60313-1.3	I883Q	Pathogenic	0.992
OPA1	O60313-1.3	I883R	Pathogenic	0.984
OPA1	O60313-1.3	I883S	Pathogenic	0.979
OPA1	O60313-1.3	I883T	Pathogenic	0.957
OPA1	O60313-1.3	I883V	Neutral	0.443
OPA1	O60313-1.3	I883W	Pathogenic	0.998
OPA1	O60313-1.3	I883Y	Pathogenic	0.978
OPA1	O60313-1.3	Q884A	Pathogenic	0.991
OPA1	O60313-1.3	Q884C	Pathogenic	0.998
OPA1	O60313-1.3	Q884D	Pathogenic	0.977
OPA1	O60313-1.3	Q884E	Pathogenic	0.857
OPA1	O60313-1.3	Q884F	Pathogenic	0.996
OPA1	O60313-1.3	Q884G	Pathogenic	0.998
OPA1	O60313-1.3	Q884H	Pathogenic	0.982
OPA1	O60313-1.3	Q884I	Pathogenic	0.996
OPA1	O60313-1.3	Q884K	Pathogenic	0.922
OPA1	O60313-1.3	Q884L	Pathogenic	0.991
OPA1	O60313-1.3	Q884M	Pathogenic	0.95
OPA1	O60313-1.3	Q884N	Pathogenic	0.98
OPA1	O60313-1.3	Q884P	Pathogenic	0.988
OPA1	O60313-1.3	Q884R	Pathogenic	0.917
OPA1	O60313-1.3	Q884S	Pathogenic	0.982
OPA1	O60313-1.3	Q884T	Pathogenic	0.992
OPA1	O60313-1.3	Q884V	Pathogenic	0.994
OPA1	O60313-1.3	Q884W	Pathogenic	0.982
OPA1	O60313-1.3	Q884Y	Pathogenic	0.985
OPA1	O60313-1.3	R885A	Pathogenic	0.795
OPA1	O60313-1.3	R885C	Pathogenic	0.95
OPA1	O60313-1.3	R885D	Pathogenic	0.971
OPA1	O60313-1.3	R885E	Pathogenic	0.788
OPA1	O60313-1.3	R885F	Pathogenic	0.916
OPA1	O60313-1.3	R885G	Pathogenic	0.933
OPA1	O60313-1.3	R885H	Pathogenic	0.656
OPA1	O60313-1.3	R885I	Pathogenic	0.911
OPA1	O60313-1.3	R885K	Neutral	0.403
OPA1	O60313-1.3	R885L	Pathogenic	0.796
OPA1	O60313-1.3	R885M	Pathogenic	0.674
OPA1	O60313-1.3	R885N	Pathogenic	0.774
OPA1	O60313-1.3	R885P	Pathogenic	0.894
OPA1	O60313-1.3	R885Q	Neutral	0.472
OPA1	O60313-1.3	R885S	Pathogenic	0.845
OPA1	O60313-1.3	R885T	Pathogenic	0.818
OPA1	O60313-1.3	R885V	Pathogenic	0.942
OPA1	O60313-1.3	R885W	Pathogenic	0.876
OPA1	O60313-1.3	R885Y	Pathogenic	0.891
OPA1	O60313-1.3	M886A	Pathogenic	0.978
OPA1	O60313-1.3	M886C	Pathogenic	0.989
OPA1	O60313-1.3	M886D	Pathogenic	0.993
OPA1	O60313-1.3	M886E	Pathogenic	0.984
OPA1	O60313-1.3	M886F	Pathogenic	0.962
OPA1	O60313-1.3	M886G	Pathogenic	0.996
OPA1	O60313-1.3	M886H	Pathogenic	0.993
OPA1	O60313-1.3	M886I	Pathogenic	0.9
OPA1	O60313-1.3	M886K	Pathogenic	0.941
OPA1	O60313-1.3	M886L	Pathogenic	0.774
OPA1	O60313-1.3	M886N	Pathogenic	0.984
OPA1	O60313-1.3	M886P	Pathogenic	0.995
OPA1	O60313-1.3	M886Q	Pathogenic	0.918
OPA1	O60313-1.3	M886R	Pathogenic	0.938
OPA1	O60313-1.3	M886S	Pathogenic	0.971
OPA1	O60313-1.3	M886T	Pathogenic	0.979
OPA1	O60313-1.3	M886V	Pathogenic	0.933
OPA1	O60313-1.3	M886W	Pathogenic	0.978
OPA1	O60313-1.3	M886Y	Pathogenic	0.989
OPA1	O60313-1.3	L887A	Pathogenic	0.881
OPA1	O60313-1.3	L887C	Pathogenic	0.936
OPA1	O60313-1.3	L887D	Pathogenic	0.987
OPA1	O60313-1.3	L887E	Pathogenic	0.968
OPA1	O60313-1.3	L887F	Pathogenic	0.909
OPA1	O60313-1.3	L887G	Pathogenic	0.992
OPA1	O60313-1.3	L887H	Pathogenic	0.985
OPA1	O60313-1.3	L887I	Pathogenic	0.55
OPA1	O60313-1.3	L887K	Pathogenic	0.886
OPA1	O60313-1.3	L887M	Neutral	0.466
OPA1	O60313-1.3	L887N	Pathogenic	0.968
OPA1	O60313-1.3	L887P	Pathogenic	0.99
OPA1	O60313-1.3	L887Q	Pathogenic	0.94
OPA1	O60313-1.3	L887R	Pathogenic	0.879
OPA1	O60313-1.3	L887S	Pathogenic	0.941
OPA1	O60313-1.3	L887T	Pathogenic	0.886
OPA1	O60313-1.3	L887V	Pathogenic	0.699
OPA1	O60313-1.3	L887W	Pathogenic	0.98
OPA1	O60313-1.3	L887Y	Pathogenic	0.94
OPA1	O60313-1.3	A888C	Neutral	0.015
OPA1	O60313-1.3	A888D	Neutral	0.078
OPA1	O60313-1.3	A888E	Neutral	0.03
OPA1	O60313-1.3	A888F	Neutral	0.047
OPA1	O60313-1.3	A888G	Neutral	0.02
OPA1	O60313-1.3	A888H	Neutral	0.149
OPA1	O60313-1.3	A888I	Neutral	0.017
OPA1	O60313-1.3	A888K	Neutral	0.02
OPA1	O60313-1.3	A888L	Neutral	0.019
OPA1	O60313-1.3	A888M	Neutral	0.029
OPA1	O60313-1.3	A888N	Neutral	0.088
OPA1	O60313-1.3	A888P	Neutral	0.051
OPA1	O60313-1.3	A888Q	Neutral	0.042
OPA1	O60313-1.3	A888R	Neutral	0.019
OPA1	O60313-1.3	A888S	Neutral	0.007
OPA1	O60313-1.3	A888T	Neutral	0.025
OPA1	O60313-1.3	A888V	Neutral	0.011
OPA1	O60313-1.3	A888W	Neutral	0.078
OPA1	O60313-1.3	A888Y	Neutral	0.094
OPA1	O60313-1.3	I889A	Pathogenic	0.656
OPA1	O60313-1.3	I889C	Pathogenic	0.792
OPA1	O60313-1.3	I889D	Pathogenic	0.867
OPA1	O60313-1.3	I889E	Pathogenic	0.888
OPA1	O60313-1.3	I889F	Pathogenic	0.752
OPA1	O60313-1.3	I889G	Pathogenic	0.97
OPA1	O60313-1.3	I889H	Pathogenic	0.943
OPA1	O60313-1.3	I889K	Pathogenic	0.853
OPA1	O60313-1.3	I889L	Neutral	0.257
OPA1	O60313-1.3	I889M	Neutral	0.395
OPA1	O60313-1.3	I889N	Pathogenic	0.886
OPA1	O60313-1.3	I889P	Pathogenic	0.962
OPA1	O60313-1.3	I889Q	Pathogenic	0.922
OPA1	O60313-1.3	I889R	Pathogenic	0.845
OPA1	O60313-1.3	I889S	Pathogenic	0.805
OPA1	O60313-1.3	I889T	Pathogenic	0.667
OPA1	O60313-1.3	I889V	Neutral	0.067
OPA1	O60313-1.3	I889W	Pathogenic	0.978
OPA1	O60313-1.3	I889Y	Pathogenic	0.801
OPA1	O60313-1.3	T890A	Pathogenic	0.985
OPA1	O60313-1.3	T890C	Pathogenic	0.991
OPA1	O60313-1.3	T890D	Pathogenic	0.988
OPA1	O60313-1.3	T890E	Pathogenic	0.989
OPA1	O60313-1.3	T890F	Pathogenic	0.992
OPA1	O60313-1.3	T890G	Pathogenic	0.998
OPA1	O60313-1.3	T890H	Pathogenic	0.998
OPA1	O60313-1.3	T890I	Pathogenic	0.979
OPA1	O60313-1.3	T890K	Pathogenic	0.983
OPA1	O60313-1.3	T890L	Pathogenic	0.981
OPA1	O60313-1.3	T890M	Pathogenic	0.988
OPA1	O60313-1.3	T890N	Pathogenic	0.971
OPA1	O60313-1.3	T890P	Pathogenic	0.993
OPA1	O60313-1.3	T890Q	Pathogenic	0.992
OPA1	O60313-1.3	T890R	Pathogenic	0.982
OPA1	O60313-1.3	T890S	Pathogenic	0.948
OPA1	O60313-1.3	T890V	Pathogenic	0.967
OPA1	O60313-1.3	T890W	Pathogenic	0.987
OPA1	O60313-1.3	T890Y	Pathogenic	0.996
OPA1	O60313-1.3	A891C	Pathogenic	0.902
OPA1	O60313-1.3	A891D	Pathogenic	0.981
OPA1	O60313-1.3	A891E	Pathogenic	0.95
OPA1	O60313-1.3	A891F	Pathogenic	0.969
OPA1	O60313-1.3	A891G	Pathogenic	0.928
OPA1	O60313-1.3	A891H	Pathogenic	0.991
OPA1	O60313-1.3	A891I	Pathogenic	0.916
OPA1	O60313-1.3	A891K	Pathogenic	0.926
OPA1	O60313-1.3	A891L	Pathogenic	0.923
OPA1	O60313-1.3	A891M	Pathogenic	0.949
OPA1	O60313-1.3	A891N	Pathogenic	0.984
OPA1	O60313-1.3	A891P	Pathogenic	0.971
OPA1	O60313-1.3	A891Q	Pathogenic	0.965
OPA1	O60313-1.3	A891R	Pathogenic	0.922
OPA1	O60313-1.3	A891S	Pathogenic	0.818
OPA1	O60313-1.3	A891T	Pathogenic	0.941
OPA1	O60313-1.3	A891V	Pathogenic	0.874
OPA1	O60313-1.3	A891W	Pathogenic	0.981
OPA1	O60313-1.3	A891Y	Pathogenic	0.985
OPA1	O60313-1.3	N892A	Pathogenic	0.996
OPA1	O60313-1.3	N892C	Pathogenic	0.998
OPA1	O60313-1.3	N892D	Pathogenic	0.961
OPA1	O60313-1.3	N892E	Pathogenic	0.987
OPA1	O60313-1.3	N892F	Pathogenic	0.995
OPA1	O60313-1.3	N892G	Pathogenic	0.976
OPA1	O60313-1.3	N892H	Pathogenic	0.932
OPA1	O60313-1.3	N892I	Pathogenic	0.995
OPA1	O60313-1.3	N892K	Pathogenic	0.981
OPA1	O60313-1.3	N892L	Pathogenic	0.996
OPA1	O60313-1.3	N892M	Pathogenic	0.992
OPA1	O60313-1.3	N892P	Pathogenic	0.995
OPA1	O60313-1.3	N892Q	Pathogenic	0.982
OPA1	O60313-1.3	N892R	Pathogenic	0.98
OPA1	O60313-1.3	N892S	Pathogenic	0.941
OPA1	O60313-1.3	N892T	Pathogenic	0.974
OPA1	O60313-1.3	N892V	Pathogenic	0.997
OPA1	O60313-1.3	N892W	Pathogenic	0.997
OPA1	O60313-1.3	N892Y	Pathogenic	0.993
OPA1	O60313-1.3	T893A	Pathogenic	0.734
OPA1	O60313-1.3	T893C	Pathogenic	0.822
OPA1	O60313-1.3	T893D	Pathogenic	0.782
OPA1	O60313-1.3	T893E	Pathogenic	0.793
OPA1	O60313-1.3	T893F	Pathogenic	0.849
OPA1	O60313-1.3	T893G	Pathogenic	0.947
OPA1	O60313-1.3	T893H	Pathogenic	0.956
OPA1	O60313-1.3	T893I	Pathogenic	0.666
OPA1	O60313-1.3	T893K	Pathogenic	0.716
OPA1	O60313-1.3	T893L	Pathogenic	0.687
OPA1	O60313-1.3	T893M	Pathogenic	0.771
OPA1	O60313-1.3	T893N	Pathogenic	0.59
OPA1	O60313-1.3	T893P	Pathogenic	0.857
OPA1	O60313-1.3	T893Q	Pathogenic	0.847
OPA1	O60313-1.3	T893R	Pathogenic	0.703
OPA1	O60313-1.3	T893S	Neutral	0.438
OPA1	O60313-1.3	T893V	Pathogenic	0.559
OPA1	O60313-1.3	T893W	Pathogenic	0.769
OPA1	O60313-1.3	T893Y	Pathogenic	0.922
OPA1	O60313-1.3	L894A	Pathogenic	0.974
OPA1	O60313-1.3	L894C	Pathogenic	0.987
OPA1	O60313-1.3	L894D	Pathogenic	0.997
OPA1	O60313-1.3	L894E	Pathogenic	0.994
OPA1	O60313-1.3	L894F	Pathogenic	0.98
OPA1	O60313-1.3	L894G	Pathogenic	0.998
OPA1	O60313-1.3	L894H	Pathogenic	0.997
OPA1	O60313-1.3	L894I	Pathogenic	0.859
OPA1	O60313-1.3	L894K	Pathogenic	0.975
OPA1	O60313-1.3	L894M	Pathogenic	0.814
OPA1	O60313-1.3	L894N	Pathogenic	0.993
OPA1	O60313-1.3	L894P	Pathogenic	0.998
OPA1	O60313-1.3	L894Q	Pathogenic	0.987
OPA1	O60313-1.3	L894R	Pathogenic	0.973
OPA1	O60313-1.3	L894S	Pathogenic	0.988
OPA1	O60313-1.3	L894T	Pathogenic	0.975
OPA1	O60313-1.3	L894V	Pathogenic	0.921
OPA1	O60313-1.3	L894W	Pathogenic	0.996
OPA1	O60313-1.3	L894Y	Pathogenic	0.987
OPA1	O60313-1.3	R895A	Pathogenic	0.978
OPA1	O60313-1.3	R895C	Pathogenic	0.995
OPA1	O60313-1.3	R895D	Pathogenic	0.997
OPA1	O60313-1.3	R895E	Pathogenic	0.977
OPA1	O60313-1.3	R895F	Pathogenic	0.992
OPA1	O60313-1.3	R895G	Pathogenic	0.994
OPA1	O60313-1.3	R895H	Pathogenic	0.956
OPA1	O60313-1.3	R895I	Pathogenic	0.992
OPA1	O60313-1.3	R895K	Pathogenic	0.885
OPA1	O60313-1.3	R895L	Pathogenic	0.978
OPA1	O60313-1.3	R895M	Pathogenic	0.959
OPA1	O60313-1.3	R895N	Pathogenic	0.975
OPA1	O60313-1.3	R895P	Pathogenic	0.99
OPA1	O60313-1.3	R895Q	Pathogenic	0.911
OPA1	O60313-1.3	R895S	Pathogenic	0.984
OPA1	O60313-1.3	R895T	Pathogenic	0.981
OPA1	O60313-1.3	R895V	Pathogenic	0.995
OPA1	O60313-1.3	R895W	Pathogenic	0.988
OPA1	O60313-1.3	R895Y	Pathogenic	0.989
OPA1	O60313-1.3	Q896A	Pathogenic	0.991
OPA1	O60313-1.3	Q896C	Pathogenic	0.998
OPA1	O60313-1.3	Q896D	Pathogenic	0.977
OPA1	O60313-1.3	Q896E	Pathogenic	0.857
OPA1	O60313-1.3	Q896F	Pathogenic	0.996
OPA1	O60313-1.3	Q896G	Pathogenic	0.998
OPA1	O60313-1.3	Q896H	Pathogenic	0.982
OPA1	O60313-1.3	Q896I	Pathogenic	0.996
OPA1	O60313-1.3	Q896K	Pathogenic	0.922
OPA1	O60313-1.3	Q896L	Pathogenic	0.991
OPA1	O60313-1.3	Q896M	Pathogenic	0.95
OPA1	O60313-1.3	Q896N	Pathogenic	0.98
OPA1	O60313-1.3	Q896P	Pathogenic	0.988
OPA1	O60313-1.3	Q896R	Pathogenic	0.917
OPA1	O60313-1.3	Q896S	Pathogenic	0.982
OPA1	O60313-1.3	Q896T	Pathogenic	0.992
OPA1	O60313-1.3	Q896V	Pathogenic	0.994
OPA1	O60313-1.3	Q896W	Pathogenic	0.982
OPA1	O60313-1.3	Q896Y	Pathogenic	0.985
OPA1	O60313-1.3	Q897A	Pathogenic	0.991
OPA1	O60313-1.3	Q897C	Pathogenic	0.998
OPA1	O60313-1.3	Q897D	Pathogenic	0.977
OPA1	O60313-1.3	Q897E	Pathogenic	0.857
OPA1	O60313-1.3	Q897F	Pathogenic	0.996
OPA1	O60313-1.3	Q897G	Pathogenic	0.998
OPA1	O60313-1.3	Q897H	Pathogenic	0.982
OPA1	O60313-1.3	Q897I	Pathogenic	0.996
OPA1	O60313-1.3	Q897K	Pathogenic	0.922
OPA1	O60313-1.3	Q897L	Pathogenic	0.991
OPA1	O60313-1.3	Q897M	Pathogenic	0.95
OPA1	O60313-1.3	Q897N	Pathogenic	0.98
OPA1	O60313-1.3	Q897P	Pathogenic	0.988
OPA1	O60313-1.3	Q897R	Pathogenic	0.917
OPA1	O60313-1.3	Q897S	Pathogenic	0.982
OPA1	O60313-1.3	Q897T	Pathogenic	0.992
OPA1	O60313-1.3	Q897V	Pathogenic	0.994
OPA1	O60313-1.3	Q897W	Pathogenic	0.982
OPA1	O60313-1.3	Q897Y	Pathogenic	0.985
OPA1	O60313-1.3	L898A	Pathogenic	0.559
OPA1	O60313-1.3	L898C	Pathogenic	0.716
OPA1	O60313-1.3	L898D	Pathogenic	0.926
OPA1	O60313-1.3	L898E	Pathogenic	0.84
OPA1	O60313-1.3	L898F	Pathogenic	0.631
OPA1	O60313-1.3	L898G	Pathogenic	0.956
OPA1	O60313-1.3	L898H	Pathogenic	0.916
OPA1	O60313-1.3	L898I	Neutral	0.173
OPA1	O60313-1.3	L898K	Pathogenic	0.571
OPA1	O60313-1.3	L898M	Neutral	0.13
OPA1	O60313-1.3	L898N	Pathogenic	0.838
OPA1	O60313-1.3	L898P	Pathogenic	0.944
OPA1	O60313-1.3	L898Q	Pathogenic	0.73
OPA1	O60313-1.3	L898R	Pathogenic	0.556
OPA1	O60313-1.3	L898S	Pathogenic	0.733
OPA1	O60313-1.3	L898T	Pathogenic	0.571
OPA1	O60313-1.3	L898V	Neutral	0.285
OPA1	O60313-1.3	L898W	Pathogenic	0.895
OPA1	O60313-1.3	L898Y	Pathogenic	0.728
OPA1	O60313-1.3	T899A	Pathogenic	0.603
OPA1	O60313-1.3	T899C	Pathogenic	0.718
OPA1	O60313-1.3	T899D	Pathogenic	0.663
OPA1	O60313-1.3	T899E	Pathogenic	0.678
OPA1	O60313-1.3	T899F	Pathogenic	0.756
OPA1	O60313-1.3	T899G	Pathogenic	0.908
OPA1	O60313-1.3	T899H	Pathogenic	0.923
OPA1	O60313-1.3	T899I	Pathogenic	0.523
OPA1	O60313-1.3	T899K	Pathogenic	0.581
OPA1	O60313-1.3	T899L	Pathogenic	0.547
OPA1	O60313-1.3	T899M	Pathogenic	0.649
OPA1	O60313-1.3	T899N	Neutral	0.441
OPA1	O60313-1.3	T899P	Pathogenic	0.767
OPA1	O60313-1.3	T899Q	Pathogenic	0.752
OPA1	O60313-1.3	T899R	Pathogenic	0.566
OPA1	O60313-1.3	T899S	Neutral	0.3
OPA1	O60313-1.3	T899V	Neutral	0.41
OPA1	O60313-1.3	T899W	Pathogenic	0.646
OPA1	O60313-1.3	T899Y	Pathogenic	0.866
OPA1	O60313-1.3	N900A	Pathogenic	0.996
OPA1	O60313-1.3	N900C	Pathogenic	0.998
OPA1	O60313-1.3	N900D	Pathogenic	0.961
OPA1	O60313-1.3	N900E	Pathogenic	0.987
OPA1	O60313-1.3	N900F	Pathogenic	0.995
OPA1	O60313-1.3	N900G	Pathogenic	0.976
OPA1	O60313-1.3	N900H	Pathogenic	0.932
OPA1	O60313-1.3	N900I	Pathogenic	0.995
OPA1	O60313-1.3	N900K	Pathogenic	0.981
OPA1	O60313-1.3	N900L	Pathogenic	0.996
OPA1	O60313-1.3	N900M	Pathogenic	0.992
OPA1	O60313-1.3	N900P	Pathogenic	0.995
OPA1	O60313-1.3	N900Q	Pathogenic	0.982
OPA1	O60313-1.3	N900R	Pathogenic	0.98
OPA1	O60313-1.3	N900S	Pathogenic	0.941
OPA1	O60313-1.3	N900T	Pathogenic	0.974
OPA1	O60313-1.3	N900V	Pathogenic	0.997
OPA1	O60313-1.3	N900W	Pathogenic	0.997
OPA1	O60313-1.3	N900Y	Pathogenic	0.993
OPA1	O60313-1.3	T901A	Pathogenic	0.813
OPA1	O60313-1.3	T901C	Pathogenic	0.88
OPA1	O60313-1.3	T901D	Pathogenic	0.85
OPA1	O60313-1.3	T901E	Pathogenic	0.858
OPA1	O60313-1.3	T901F	Pathogenic	0.899
OPA1	O60313-1.3	T901G	Pathogenic	0.966
OPA1	O60313-1.3	T901H	Pathogenic	0.972
OPA1	O60313-1.3	T901I	Pathogenic	0.759
OPA1	O60313-1.3	T901K	Pathogenic	0.799
OPA1	O60313-1.3	T901L	Pathogenic	0.776
OPA1	O60313-1.3	T901M	Pathogenic	0.842
OPA1	O60313-1.3	T901N	Pathogenic	0.694
OPA1	O60313-1.3	T901P	Pathogenic	0.904
OPA1	O60313-1.3	T901Q	Pathogenic	0.897
OPA1	O60313-1.3	T901R	Pathogenic	0.789
OPA1	O60313-1.3	T901S	Pathogenic	0.551
OPA1	O60313-1.3	T901V	Pathogenic	0.666
OPA1	O60313-1.3	T901W	Pathogenic	0.84
OPA1	O60313-1.3	T901Y	Pathogenic	0.949
OPA1	O60313-1.3	E902A	Pathogenic	0.984
OPA1	O60313-1.3	E902C	Pathogenic	0.999
OPA1	O60313-1.3	E902D	Pathogenic	0.857
OPA1	O60313-1.3	E902F	Pathogenic	0.993
OPA1	O60313-1.3	E902G	Pathogenic	0.996
OPA1	O60313-1.3	E902H	Pathogenic	0.967
OPA1	O60313-1.3	E902I	Pathogenic	0.993
OPA1	O60313-1.3	E902K	Pathogenic	0.932
OPA1	O60313-1.3	E902L	Pathogenic	0.994
OPA1	O60313-1.3	E902M	Pathogenic	0.989
OPA1	O60313-1.3	E902N	Pathogenic	0.982
OPA1	O60313-1.3	E902P	Pathogenic	0.979
OPA1	O60313-1.3	E902Q	Pathogenic	0.829
OPA1	O60313-1.3	E902R	Pathogenic	0.974
OPA1	O60313-1.3	E902S	Pathogenic	0.968
OPA1	O60313-1.3	E902T	Pathogenic	0.987
OPA1	O60313-1.3	E902V	Pathogenic	0.989
OPA1	O60313-1.3	E902W	Pathogenic	0.989
OPA1	O60313-1.3	E902Y	Pathogenic	0.991
OPA1	O60313-1.3	V903A	Pathogenic	0.551
OPA1	O60313-1.3	V903C	Pathogenic	0.876
OPA1	O60313-1.3	V903D	Pathogenic	0.924
OPA1	O60313-1.3	V903E	Pathogenic	0.831
OPA1	O60313-1.3	V903F	Pathogenic	0.833
OPA1	O60313-1.3	V903G	Pathogenic	0.955
OPA1	O60313-1.3	V903H	Pathogenic	0.965
OPA1	O60313-1.3	V903I	Neutral	0.068
OPA1	O60313-1.3	V903K	Pathogenic	0.764
OPA1	O60313-1.3	V903L	Neutral	0.401
OPA1	O60313-1.3	V903M	Pathogenic	0.507
OPA1	O60313-1.3	V903N	Pathogenic	0.935
OPA1	O60313-1.3	V903P	Pathogenic	0.942
OPA1	O60313-1.3	V903Q	Pathogenic	0.876
OPA1	O60313-1.3	V903R	Pathogenic	0.898
OPA1	O60313-1.3	V903S	Pathogenic	0.885
OPA1	O60313-1.3	V903T	Pathogenic	0.563
OPA1	O60313-1.3	V903W	Pathogenic	0.961
OPA1	O60313-1.3	V903Y	Pathogenic	0.867
OPA1	O60313-1.3	R904A	Pathogenic	0.968
OPA1	O60313-1.3	R904C	Pathogenic	0.993
OPA1	O60313-1.3	R904D	Pathogenic	0.996
OPA1	O60313-1.3	R904E	Pathogenic	0.967
OPA1	O60313-1.3	R904F	Pathogenic	0.988
OPA1	O60313-1.3	R904G	Pathogenic	0.991
OPA1	O60313-1.3	R904H	Pathogenic	0.937
OPA1	O60313-1.3	R904I	Pathogenic	0.988
OPA1	O60313-1.3	R904K	Pathogenic	0.84
OPA1	O60313-1.3	R904L	Pathogenic	0.968
OPA1	O60313-1.3	R904M	Pathogenic	0.941
OPA1	O60313-1.3	R904N	Pathogenic	0.964
OPA1	O60313-1.3	R904P	Pathogenic	0.985
OPA1	O60313-1.3	R904Q	Pathogenic	0.874
OPA1	O60313-1.3	R904S	Pathogenic	0.977
OPA1	O60313-1.3	R904T	Pathogenic	0.972
OPA1	O60313-1.3	R904V	Pathogenic	0.992
OPA1	O60313-1.3	R904W	Pathogenic	0.982
OPA1	O60313-1.3	R904Y	Pathogenic	0.985
OPA1	O60313-1.3	R905A	Pathogenic	0.972
OPA1	O60313-1.3	R905C	Pathogenic	0.994
OPA1	O60313-1.3	R905D	Pathogenic	0.997
OPA1	O60313-1.3	R905E	Pathogenic	0.97
OPA1	O60313-1.3	R905F	Pathogenic	0.99
OPA1	O60313-1.3	R905G	Pathogenic	0.992
OPA1	O60313-1.3	R905H	Pathogenic	0.944
OPA1	O60313-1.3	R905I	Pathogenic	0.989
OPA1	O60313-1.3	R905K	Pathogenic	0.855
OPA1	O60313-1.3	R905L	Pathogenic	0.972
OPA1	O60313-1.3	R905M	Pathogenic	0.948
OPA1	O60313-1.3	R905N	Pathogenic	0.968
OPA1	O60313-1.3	R905P	Pathogenic	0.987
OPA1	O60313-1.3	R905Q	Pathogenic	0.887
OPA1	O60313-1.3	R905S	Pathogenic	0.98
OPA1	O60313-1.3	R905T	Pathogenic	0.975
OPA1	O60313-1.3	R905V	Pathogenic	0.993
OPA1	O60313-1.3	R905W	Pathogenic	0.984
OPA1	O60313-1.3	R905Y	Pathogenic	0.986
OPA1	O60313-1.3	L906A	Pathogenic	0.966
OPA1	O60313-1.3	L906C	Pathogenic	0.983
OPA1	O60313-1.3	L906D	Pathogenic	0.996
OPA1	O60313-1.3	L906E	Pathogenic	0.992
OPA1	O60313-1.3	L906F	Pathogenic	0.975
OPA1	O60313-1.3	L906G	Pathogenic	0.998
OPA1	O60313-1.3	L906H	Pathogenic	0.996
OPA1	O60313-1.3	L906I	Pathogenic	0.825
OPA1	O60313-1.3	L906K	Pathogenic	0.968
OPA1	O60313-1.3	L906M	Pathogenic	0.771
OPA1	O60313-1.3	L906N	Pathogenic	0.991
OPA1	O60313-1.3	L906P	Pathogenic	0.997
OPA1	O60313-1.3	L906Q	Pathogenic	0.984
OPA1	O60313-1.3	L906R	Pathogenic	0.966
OPA1	O60313-1.3	L906S	Pathogenic	0.984
OPA1	O60313-1.3	L906T	Pathogenic	0.968
OPA1	O60313-1.3	L906V	Pathogenic	0.9
OPA1	O60313-1.3	L906W	Pathogenic	0.995
OPA1	O60313-1.3	L906Y	Pathogenic	0.984
OPA1	O60313-1.3	E907A	Pathogenic	0.812
OPA1	O60313-1.3	E907C	Pathogenic	0.984
OPA1	O60313-1.3	E907D	Neutral	0.29
OPA1	O60313-1.3	E907F	Pathogenic	0.909
OPA1	O60313-1.3	E907G	Pathogenic	0.939
OPA1	O60313-1.3	E907H	Pathogenic	0.665
OPA1	O60313-1.3	E907I	Pathogenic	0.911
OPA1	O60313-1.3	E907K	Neutral	0.485
OPA1	O60313-1.3	E907L	Pathogenic	0.918
OPA1	O60313-1.3	E907M	Pathogenic	0.856
OPA1	O60313-1.3	E907N	Pathogenic	0.793
OPA1	O60313-1.3	E907P	Pathogenic	0.764
OPA1	O60313-1.3	E907Q	Neutral	0.248
OPA1	O60313-1.3	E907R	Pathogenic	0.719
OPA1	O60313-1.3	E907S	Pathogenic	0.676
OPA1	O60313-1.3	E907T	Pathogenic	0.833
OPA1	O60313-1.3	E907V	Pathogenic	0.863
OPA1	O60313-1.3	E907W	Pathogenic	0.854
OPA1	O60313-1.3	E907Y	Pathogenic	0.877
OPA1	O60313-1.3	K908A	Pathogenic	0.97
OPA1	O60313-1.3	K908C	Pathogenic	0.994
OPA1	O60313-1.3	K908D	Pathogenic	0.99
OPA1	O60313-1.3	K908E	Pathogenic	0.915
OPA1	O60313-1.3	K908F	Pathogenic	0.989
OPA1	O60313-1.3	K908G	Pathogenic	0.991
OPA1	O60313-1.3	K908H	Pathogenic	0.979
OPA1	O60313-1.3	K908I	Pathogenic	0.989
OPA1	O60313-1.3	K908L	Pathogenic	0.97
OPA1	O60313-1.3	K908M	Pathogenic	0.945
OPA1	O60313-1.3	K908N	Pathogenic	0.966
OPA1	O60313-1.3	K908P	Pathogenic	0.961
OPA1	O60313-1.3	K908Q	Pathogenic	0.882
OPA1	O60313-1.3	K908R	Pathogenic	0.842
OPA1	O60313-1.3	K908S	Pathogenic	0.94
OPA1	O60313-1.3	K908T	Pathogenic	0.974
OPA1	O60313-1.3	K908V	Pathogenic	0.979
OPA1	O60313-1.3	K908W	Pathogenic	0.982
OPA1	O60313-1.3	K908Y	Pathogenic	0.985
OPA1	O60313-1.3	N909A	Pathogenic	0.902
OPA1	O60313-1.3	N909C	Pathogenic	0.939
OPA1	O60313-1.3	N909D	Neutral	0.449
OPA1	O60313-1.3	N909E	Pathogenic	0.721
OPA1	O60313-1.3	N909F	Pathogenic	0.869
OPA1	O60313-1.3	N909G	Pathogenic	0.575
OPA1	O60313-1.3	N909H	Neutral	0.313
OPA1	O60313-1.3	N909I	Pathogenic	0.872
OPA1	O60313-1.3	N909K	Pathogenic	0.63
OPA1	O60313-1.3	N909L	Pathogenic	0.882
OPA1	O60313-1.3	N909M	Pathogenic	0.799
OPA1	O60313-1.3	N909P	Pathogenic	0.873
OPA1	O60313-1.3	N909Q	Pathogenic	0.649
OPA1	O60313-1.3	N909R	Pathogenic	0.615
OPA1	O60313-1.3	N909S	Neutral	0.347
OPA1	O60313-1.3	N909T	Pathogenic	0.559
OPA1	O60313-1.3	N909V	Pathogenic	0.926
OPA1	O60313-1.3	N909W	Pathogenic	0.919
OPA1	O60313-1.3	N909Y	Pathogenic	0.827
OPA1	O60313-1.3	V910A	Pathogenic	0.64
OPA1	O60313-1.3	V910C	Pathogenic	0.911
OPA1	O60313-1.3	V910D	Pathogenic	0.946
OPA1	O60313-1.3	V910E	Pathogenic	0.877
OPA1	O60313-1.3	V910F	Pathogenic	0.879
OPA1	O60313-1.3	V910G	Pathogenic	0.968
OPA1	O60313-1.3	V910H	Pathogenic	0.976
OPA1	O60313-1.3	V910I	Neutral	0.095
OPA1	O60313-1.3	V910K	Pathogenic	0.824
OPA1	O60313-1.3	V910L	Neutral	0.493
OPA1	O60313-1.3	V910M	Pathogenic	0.599
OPA1	O60313-1.3	V910N	Pathogenic	0.955
OPA1	O60313-1.3	V910P	Pathogenic	0.96
OPA1	O60313-1.3	V910Q	Pathogenic	0.911
OPA1	O60313-1.3	V910R	Pathogenic	0.927
OPA1	O60313-1.3	V910S	Pathogenic	0.918
OPA1	O60313-1.3	V910T	Pathogenic	0.651
OPA1	O60313-1.3	V910W	Pathogenic	0.973
OPA1	O60313-1.3	V910Y	Pathogenic	0.904
OPA1	O60313-1.3	K911A	Pathogenic	0.97
OPA1	O60313-1.3	K911C	Pathogenic	0.994
OPA1	O60313-1.3	K911D	Pathogenic	0.99
OPA1	O60313-1.3	K911E	Pathogenic	0.915
OPA1	O60313-1.3	K911F	Pathogenic	0.989
OPA1	O60313-1.3	K911G	Pathogenic	0.991
OPA1	O60313-1.3	K911H	Pathogenic	0.979
OPA1	O60313-1.3	K911I	Pathogenic	0.989
OPA1	O60313-1.3	K911L	Pathogenic	0.97
OPA1	O60313-1.3	K911M	Pathogenic	0.945
OPA1	O60313-1.3	K911N	Pathogenic	0.966
OPA1	O60313-1.3	K911P	Pathogenic	0.961
OPA1	O60313-1.3	K911Q	Pathogenic	0.882
OPA1	O60313-1.3	K911R	Pathogenic	0.842
OPA1	O60313-1.3	K911S	Pathogenic	0.94
OPA1	O60313-1.3	K911T	Pathogenic	0.974
OPA1	O60313-1.3	K911V	Pathogenic	0.979
OPA1	O60313-1.3	K911W	Pathogenic	0.982
OPA1	O60313-1.3	K911Y	Pathogenic	0.985
OPA1	O60313-1.3	E912A	Pathogenic	0.98
OPA1	O60313-1.3	E912C	Pathogenic	0.999
OPA1	O60313-1.3	E912D	Pathogenic	0.822
OPA1	O60313-1.3	E912F	Pathogenic	0.991
OPA1	O60313-1.3	E912G	Pathogenic	0.994
OPA1	O60313-1.3	E912H	Pathogenic	0.957
OPA1	O60313-1.3	E912I	Pathogenic	0.991
OPA1	O60313-1.3	E912K	Pathogenic	0.914
OPA1	O60313-1.3	E912L	Pathogenic	0.992
OPA1	O60313-1.3	E912M	Pathogenic	0.985
OPA1	O60313-1.3	E912N	Pathogenic	0.977
OPA1	O60313-1.3	E912P	Pathogenic	0.973
OPA1	O60313-1.3	E912Q	Pathogenic	0.788
OPA1	O60313-1.3	E912R	Pathogenic	0.967
OPA1	O60313-1.3	E912S	Pathogenic	0.959
OPA1	O60313-1.3	E912T	Pathogenic	0.983
OPA1	O60313-1.3	E912V	Pathogenic	0.986
OPA1	O60313-1.3	E912W	Pathogenic	0.985
OPA1	O60313-1.3	E912Y	Pathogenic	0.988
OPA1	O60313-1.3	V913A	Pathogenic	0.952
OPA1	O60313-1.3	V913C	Pathogenic	0.991
OPA1	O60313-1.3	V913D	Pathogenic	0.995
OPA1	O60313-1.3	V913E	Pathogenic	0.988
OPA1	O60313-1.3	V913F	Pathogenic	0.988
OPA1	O60313-1.3	V913G	Pathogenic	0.997
OPA1	O60313-1.3	V913H	Pathogenic	0.998
OPA1	O60313-1.3	V913I	Pathogenic	0.543
OPA1	O60313-1.3	V913K	Pathogenic	0.981
OPA1	O60313-1.3	V913L	Pathogenic	0.916
OPA1	O60313-1.3	V913M	Pathogenic	0.944
OPA1	O60313-1.3	V913N	Pathogenic	0.996
OPA1	O60313-1.3	V913P	Pathogenic	0.996
OPA1	O60313-1.3	V913Q	Pathogenic	0.991
OPA1	O60313-1.3	V913R	Pathogenic	0.993
OPA1	O60313-1.3	V913S	Pathogenic	0.992
OPA1	O60313-1.3	V913T	Pathogenic	0.955
OPA1	O60313-1.3	V913W	Pathogenic	0.998
OPA1	O60313-1.3	V913Y	Pathogenic	0.991
OPA1	O60313-1.3	L914A	Pathogenic	0.966
OPA1	O60313-1.3	L914C	Pathogenic	0.983
OPA1	O60313-1.3	L914D	Pathogenic	0.996
OPA1	O60313-1.3	L914E	Pathogenic	0.992
OPA1	O60313-1.3	L914F	Pathogenic	0.975
OPA1	O60313-1.3	L914G	Pathogenic	0.998
OPA1	O60313-1.3	L914H	Pathogenic	0.996
OPA1	O60313-1.3	L914I	Pathogenic	0.825
OPA1	O60313-1.3	L914K	Pathogenic	0.968
OPA1	O60313-1.3	L914M	Pathogenic	0.771
OPA1	O60313-1.3	L914N	Pathogenic	0.991
OPA1	O60313-1.3	L914P	Pathogenic	0.997
OPA1	O60313-1.3	L914Q	Pathogenic	0.984
OPA1	O60313-1.3	L914R	Pathogenic	0.966
OPA1	O60313-1.3	L914S	Pathogenic	0.984
OPA1	O60313-1.3	L914T	Pathogenic	0.968
OPA1	O60313-1.3	L914V	Pathogenic	0.9
OPA1	O60313-1.3	L914W	Pathogenic	0.995
OPA1	O60313-1.3	L914Y	Pathogenic	0.984
OPA1	O60313-1.3	E915A	Pathogenic	0.82
OPA1	O60313-1.3	E915C	Pathogenic	0.985
OPA1	O60313-1.3	E915D	Neutral	0.301
OPA1	O60313-1.3	E915F	Pathogenic	0.913
OPA1	O60313-1.3	E915G	Pathogenic	0.942
OPA1	O60313-1.3	E915H	Pathogenic	0.676
OPA1	O60313-1.3	E915I	Pathogenic	0.915
OPA1	O60313-1.3	E915K	Neutral	0.498
OPA1	O60313-1.3	E915L	Pathogenic	0.922
OPA1	O60313-1.3	E915M	Pathogenic	0.862
OPA1	O60313-1.3	E915N	Pathogenic	0.801
OPA1	O60313-1.3	E915P	Pathogenic	0.773
OPA1	O60313-1.3	E915Q	Neutral	0.258
OPA1	O60313-1.3	E915R	Pathogenic	0.73
OPA1	O60313-1.3	E915S	Pathogenic	0.688
OPA1	O60313-1.3	E915T	Pathogenic	0.84
OPA1	O60313-1.3	E915V	Pathogenic	0.869
OPA1	O60313-1.3	E915W	Pathogenic	0.861
OPA1	O60313-1.3	E915Y	Pathogenic	0.883
OPA1	O60313-1.3	D916A	Pathogenic	0.985
OPA1	O60313-1.3	D916C	Pathogenic	0.991
OPA1	O60313-1.3	D916E	Pathogenic	0.694
OPA1	O60313-1.3	D916F	Pathogenic	0.979
OPA1	O60313-1.3	D916G	Pathogenic	0.966
OPA1	O60313-1.3	D916H	Pathogenic	0.963
OPA1	O60313-1.3	D916I	Pathogenic	0.979
OPA1	O60313-1.3	D916K	Pathogenic	0.979
OPA1	O60313-1.3	D916L	Pathogenic	0.993
OPA1	O60313-1.3	D916M	Pathogenic	0.988
OPA1	O60313-1.3	D916N	Pathogenic	0.87
OPA1	O60313-1.3	D916P	Pathogenic	0.944
OPA1	O60313-1.3	D916Q	Pathogenic	0.927
OPA1	O60313-1.3	D916R	Pathogenic	0.992
OPA1	O60313-1.3	D916S	Pathogenic	0.917
OPA1	O60313-1.3	D916T	Pathogenic	0.963
OPA1	O60313-1.3	D916V	Pathogenic	0.989
OPA1	O60313-1.3	D916W	Pathogenic	0.987
OPA1	O60313-1.3	D916Y	Pathogenic	0.99
OPA1	O60313-1.3	F917A	Pathogenic	0.925
OPA1	O60313-1.3	F917C	Pathogenic	0.961
OPA1	O60313-1.3	F917D	Pathogenic	0.936
OPA1	O60313-1.3	F917E	Pathogenic	0.946
OPA1	O60313-1.3	F917G	Pathogenic	0.962
OPA1	O60313-1.3	F917H	Pathogenic	0.815
OPA1	O60313-1.3	F917I	Pathogenic	0.875
OPA1	O60313-1.3	F917K	Pathogenic	0.934
OPA1	O60313-1.3	F917L	Pathogenic	0.867
OPA1	O60313-1.3	F917M	Pathogenic	0.809
OPA1	O60313-1.3	F917N	Pathogenic	0.946
OPA1	O60313-1.3	F917P	Pathogenic	0.994
OPA1	O60313-1.3	F917Q	Pathogenic	0.964
OPA1	O60313-1.3	F917R	Pathogenic	0.93
OPA1	O60313-1.3	F917S	Pathogenic	0.902
OPA1	O60313-1.3	F917T	Pathogenic	0.929
OPA1	O60313-1.3	F917V	Pathogenic	0.919
OPA1	O60313-1.3	F917W	Pathogenic	0.6
OPA1	O60313-1.3	F917Y	Neutral	0.122
OPA1	O60313-1.3	A918C	Neutral	0.173
OPA1	O60313-1.3	A918D	Pathogenic	0.544
OPA1	O60313-1.3	A918E	Neutral	0.303
OPA1	O60313-1.3	A918F	Neutral	0.412
OPA1	O60313-1.3	A918G	Neutral	0.226
OPA1	O60313-1.3	A918H	Pathogenic	0.711
OPA1	O60313-1.3	A918I	Neutral	0.199
OPA1	O60313-1.3	A918K	Neutral	0.222
OPA1	O60313-1.3	A918L	Neutral	0.214
OPA1	O60313-1.3	A918M	Neutral	0.295
OPA1	O60313-1.3	A918N	Pathogenic	0.577
OPA1	O60313-1.3	A918P	Neutral	0.432
OPA1	O60313-1.3	A918Q	Neutral	0.384
OPA1	O60313-1.3	A918R	Neutral	0.212
OPA1	O60313-1.3	A918S	Neutral	0.093
OPA1	O60313-1.3	A918T	Neutral	0.265
OPA1	O60313-1.3	A918V	Neutral	0.136
OPA1	O60313-1.3	A918W	Pathogenic	0.545
OPA1	O60313-1.3	A918Y	Pathogenic	0.594
OPA1	O60313-1.3	E919A	Pathogenic	0.613
OPA1	O60313-1.3	E919C	Pathogenic	0.957
OPA1	O60313-1.3	E919D	Neutral	0.13
OPA1	O60313-1.3	E919F	Pathogenic	0.785
OPA1	O60313-1.3	E919G	Pathogenic	0.85
OPA1	O60313-1.3	E919H	Neutral	0.421
OPA1	O60313-1.3	E919I	Pathogenic	0.79
OPA1	O60313-1.3	E919K	Neutral	0.257
OPA1	O60313-1.3	E919L	Pathogenic	0.805
OPA1	O60313-1.3	E919M	Pathogenic	0.686
OPA1	O60313-1.3	E919N	Pathogenic	0.584
OPA1	O60313-1.3	E919P	Pathogenic	0.543
OPA1	O60313-1.3	E919Q	Neutral	0.108
OPA1	O60313-1.3	E919R	Neutral	0.485
OPA1	O60313-1.3	E919S	Neutral	0.434
OPA1	O60313-1.3	E919T	Pathogenic	0.647
OPA1	O60313-1.3	E919V	Pathogenic	0.698
OPA1	O60313-1.3	E919W	Pathogenic	0.683
OPA1	O60313-1.3	E919Y	Pathogenic	0.724
OPA1	O60313-1.3	D920A	Pathogenic	0.989
OPA1	O60313-1.3	D920C	Pathogenic	0.993
OPA1	O60313-1.3	D920E	Pathogenic	0.755
OPA1	O60313-1.3	D920F	Pathogenic	0.984
OPA1	O60313-1.3	D920G	Pathogenic	0.975
OPA1	O60313-1.3	D920H	Pathogenic	0.973
OPA1	O60313-1.3	D920I	Pathogenic	0.985
OPA1	O60313-1.3	D920K	Pathogenic	0.984
OPA1	O60313-1.3	D920L	Pathogenic	0.995
OPA1	O60313-1.3	D920M	Pathogenic	0.991
OPA1	O60313-1.3	D920N	Pathogenic	0.901
OPA1	O60313-1.3	D920P	Pathogenic	0.959
OPA1	O60313-1.3	D920Q	Pathogenic	0.946
OPA1	O60313-1.3	D920R	Pathogenic	0.994
OPA1	O60313-1.3	D920S	Pathogenic	0.937
OPA1	O60313-1.3	D920T	Pathogenic	0.972
OPA1	O60313-1.3	D920V	Pathogenic	0.992
OPA1	O60313-1.3	D920W	Pathogenic	0.991
OPA1	O60313-1.3	D920Y	Pathogenic	0.992
OPA1	O60313-1.3	G921A	Neutral	0.003
OPA1	O60313-1.3	G921C	Neutral	0.037
OPA1	O60313-1.3	G921D	Neutral	0.005
OPA1	O60313-1.3	G921E	Neutral	0.016
OPA1	O60313-1.3	G921F	Neutral	0.015
OPA1	O60313-1.3	G921H	Neutral	0.025
OPA1	O60313-1.3	G921I	Neutral	0.044
OPA1	O60313-1.3	G921K	Neutral	0.011
OPA1	O60313-1.3	G921L	Neutral	0.048
OPA1	O60313-1.3	G921M	Neutral	0.026
OPA1	O60313-1.3	G921N	Neutral	0.002
OPA1	O60313-1.3	G921P	Neutral	0.016
OPA1	O60313-1.3	G921Q	Neutral	0.023
OPA1	O60313-1.3	G921R	Neutral	0.01
OPA1	O60313-1.3	G921S	Neutral	0.004
OPA1	O60313-1.3	G921T	Neutral	0.024
OPA1	O60313-1.3	G921V	Neutral	0.028
OPA1	O60313-1.3	G921W	Neutral	0.003
OPA1	O60313-1.3	G921Y	Neutral	0.031
OPA1	O60313-1.3	E922A	Pathogenic	0.686
OPA1	O60313-1.3	E922C	Pathogenic	0.969
OPA1	O60313-1.3	E922D	Neutral	0.171
OPA1	O60313-1.3	E922F	Pathogenic	0.834
OPA1	O60313-1.3	E922G	Pathogenic	0.887
OPA1	O60313-1.3	E922H	Pathogenic	0.501
OPA1	O60313-1.3	E922I	Pathogenic	0.838
OPA1	O60313-1.3	E922K	Neutral	0.322
OPA1	O60313-1.3	E922L	Pathogenic	0.85
OPA1	O60313-1.3	E922M	Pathogenic	0.751
OPA1	O60313-1.3	E922N	Pathogenic	0.659
OPA1	O60313-1.3	E922P	Pathogenic	0.621
OPA1	O60313-1.3	E922Q	Neutral	0.143
OPA1	O60313-1.3	E922R	Pathogenic	0.565
OPA1	O60313-1.3	E922S	Pathogenic	0.514
OPA1	O60313-1.3	E922T	Pathogenic	0.716
OPA1	O60313-1.3	E922V	Pathogenic	0.761
OPA1	O60313-1.3	E922W	Pathogenic	0.748
OPA1	O60313-1.3	E922Y	Pathogenic	0.784
OPA1	O60313-1.3	K923A	Pathogenic	0.584
OPA1	O60313-1.3	K923C	Pathogenic	0.872
OPA1	O60313-1.3	K923D	Pathogenic	0.805
OPA1	O60313-1.3	K923E	Neutral	0.317
OPA1	O60313-1.3	K923F	Pathogenic	0.797
OPA1	O60313-1.3	K923G	Pathogenic	0.834
OPA1	O60313-1.3	K923H	Pathogenic	0.666
OPA1	O60313-1.3	K923I	Pathogenic	0.788
OPA1	O60313-1.3	K923L	Pathogenic	0.584
OPA1	O60313-1.3	K923M	Neutral	0.427
OPA1	O60313-1.3	K923N	Pathogenic	0.553
OPA1	O60313-1.3	K923P	Pathogenic	0.512
OPA1	O60313-1.3	K923Q	Neutral	0.244
OPA1	O60313-1.3	K923R	Neutral	0.186
OPA1	O60313-1.3	K923S	Neutral	0.404
OPA1	O60313-1.3	K923T	Pathogenic	0.618
OPA1	O60313-1.3	K923V	Pathogenic	0.671
OPA1	O60313-1.3	K923W	Pathogenic	0.698
OPA1	O60313-1.3	K923Y	Pathogenic	0.738
OPA1	O60313-1.3	K924A	Pathogenic	0.97
OPA1	O60313-1.3	K924C	Pathogenic	0.994
OPA1	O60313-1.3	K924D	Pathogenic	0.99
OPA1	O60313-1.3	K924E	Pathogenic	0.915
OPA1	O60313-1.3	K924F	Pathogenic	0.989
OPA1	O60313-1.3	K924G	Pathogenic	0.991
OPA1	O60313-1.3	K924H	Pathogenic	0.979
OPA1	O60313-1.3	K924I	Pathogenic	0.989
OPA1	O60313-1.3	K924L	Pathogenic	0.97
OPA1	O60313-1.3	K924M	Pathogenic	0.945
OPA1	O60313-1.3	K924N	Pathogenic	0.966
OPA1	O60313-1.3	K924P	Pathogenic	0.961
OPA1	O60313-1.3	K924Q	Pathogenic	0.882
OPA1	O60313-1.3	K924R	Pathogenic	0.842
OPA1	O60313-1.3	K924S	Pathogenic	0.94
OPA1	O60313-1.3	K924T	Pathogenic	0.974
OPA1	O60313-1.3	K924V	Pathogenic	0.979
OPA1	O60313-1.3	K924W	Pathogenic	0.982
OPA1	O60313-1.3	K924Y	Pathogenic	0.985
OPA1	O60313-1.3	I925A	Neutral	0.003
OPA1	O60313-1.3	I925C	Neutral	0.006
OPA1	O60313-1.3	I925D	Neutral	0.009
OPA1	O60313-1.3	I925E	Neutral	0.011
OPA1	O60313-1.3	I925F	Neutral	0.004
OPA1	O60313-1.3	I925G	Neutral	0.046
OPA1	O60313-1.3	I925H	Neutral	0.024
OPA1	O60313-1.3	I925K	Neutral	0.008
OPA1	O60313-1.3	I925L	Neutral	0.001
OPA1	O60313-1.3	I925M	Neutral	0.001
OPA1	O60313-1.3	I925N	Neutral	0.011
OPA1	O60313-1.3	I925P	Neutral	0.036
OPA1	O60313-1.3	I925Q	Neutral	0.017
OPA1	O60313-1.3	I925R	Neutral	0.008
OPA1	O60313-1.3	I925S	Neutral	0.006
OPA1	O60313-1.3	I925T	Neutral	0.003
OPA1	O60313-1.3	I925V	Neutral	0.0
OPA1	O60313-1.3	I925W	Neutral	0.061
OPA1	O60313-1.3	I925Y	Neutral	0.006
OPA1	O60313-1.3	K926A	Neutral	0.093
OPA1	O60313-1.3	K926C	Neutral	0.333
OPA1	O60313-1.3	K926D	Neutral	0.231
OPA1	O60313-1.3	K926E	Neutral	0.033
OPA1	O60313-1.3	K926F	Neutral	0.222
OPA1	O60313-1.3	K926G	Neutral	0.268
OPA1	O60313-1.3	K926H	Neutral	0.127
OPA1	O60313-1.3	K926I	Neutral	0.213
OPA1	O60313-1.3	K926L	Neutral	0.093
OPA1	O60313-1.3	K926M	Neutral	0.052
OPA1	O60313-1.3	K926N	Neutral	0.083
OPA1	O60313-1.3	K926P	Neutral	0.071
OPA1	O60313-1.3	K926Q	Neutral	0.023
OPA1	O60313-1.3	K926R	Neutral	0.016
OPA1	O60313-1.3	K926S	Neutral	0.047
OPA1	O60313-1.3	K926T	Neutral	0.106
OPA1	O60313-1.3	K926V	Neutral	0.13
OPA1	O60313-1.3	K926W	Neutral	0.144
OPA1	O60313-1.3	K926Y	Neutral	0.171
OPA1	O60313-1.3	L927A	Pathogenic	0.966
OPA1	O60313-1.3	L927C	Pathogenic	0.983
OPA1	O60313-1.3	L927D	Pathogenic	0.996
OPA1	O60313-1.3	L927E	Pathogenic	0.992
OPA1	O60313-1.3	L927F	Pathogenic	0.975
OPA1	O60313-1.3	L927G	Pathogenic	0.998
OPA1	O60313-1.3	L927H	Pathogenic	0.996
OPA1	O60313-1.3	L927I	Pathogenic	0.825
OPA1	O60313-1.3	L927K	Pathogenic	0.968
OPA1	O60313-1.3	L927M	Pathogenic	0.771
OPA1	O60313-1.3	L927N	Pathogenic	0.991
OPA1	O60313-1.3	L927P	Pathogenic	0.997
OPA1	O60313-1.3	L927Q	Pathogenic	0.984
OPA1	O60313-1.3	L927R	Pathogenic	0.966
OPA1	O60313-1.3	L927S	Pathogenic	0.984
OPA1	O60313-1.3	L927T	Pathogenic	0.968
OPA1	O60313-1.3	L927V	Pathogenic	0.9
OPA1	O60313-1.3	L927W	Pathogenic	0.995
OPA1	O60313-1.3	L927Y	Pathogenic	0.984
OPA1	O60313-1.3	L928A	Pathogenic	0.722
OPA1	O60313-1.3	L928C	Pathogenic	0.838
OPA1	O60313-1.3	L928D	Pathogenic	0.963
OPA1	O60313-1.3	L928E	Pathogenic	0.915
OPA1	O60313-1.3	L928F	Pathogenic	0.778
OPA1	O60313-1.3	L928G	Pathogenic	0.978
OPA1	O60313-1.3	L928H	Pathogenic	0.957
OPA1	O60313-1.3	L928I	Neutral	0.3
OPA1	O60313-1.3	L928K	Pathogenic	0.731
OPA1	O60313-1.3	L928M	Neutral	0.235
OPA1	O60313-1.3	L928N	Pathogenic	0.914
OPA1	O60313-1.3	L928P	Pathogenic	0.972
OPA1	O60313-1.3	L928Q	Pathogenic	0.847
OPA1	O60313-1.3	L928R	Pathogenic	0.719
OPA1	O60313-1.3	L928S	Pathogenic	0.849
OPA1	O60313-1.3	L928T	Pathogenic	0.732
OPA1	O60313-1.3	L928V	Neutral	0.45
OPA1	O60313-1.3	L928W	Pathogenic	0.946
OPA1	O60313-1.3	L928Y	Pathogenic	0.845
OPA1	O60313-1.3	T929A	Pathogenic	0.98
OPA1	O60313-1.3	T929C	Pathogenic	0.988
OPA1	O60313-1.3	T929D	Pathogenic	0.985
OPA1	O60313-1.3	T929E	Pathogenic	0.986
OPA1	O60313-1.3	T929F	Pathogenic	0.99
OPA1	O60313-1.3	T929G	Pathogenic	0.997
OPA1	O60313-1.3	T929H	Pathogenic	0.997
OPA1	O60313-1.3	T929I	Pathogenic	0.973
OPA1	O60313-1.3	T929K	Pathogenic	0.979
OPA1	O60313-1.3	T929L	Pathogenic	0.975
OPA1	O60313-1.3	T929M	Pathogenic	0.984
OPA1	O60313-1.3	T929N	Pathogenic	0.963
OPA1	O60313-1.3	T929P	Pathogenic	0.991
OPA1	O60313-1.3	T929Q	Pathogenic	0.99
OPA1	O60313-1.3	T929R	Pathogenic	0.977
OPA1	O60313-1.3	T929S	Pathogenic	0.934
OPA1	O60313-1.3	T929V	Pathogenic	0.958
OPA1	O60313-1.3	T929W	Pathogenic	0.984
OPA1	O60313-1.3	T929Y	Pathogenic	0.995
OPA1	O60313-1.3	G930A	Pathogenic	0.983
OPA1	O60313-1.3	G930C	Pathogenic	0.999
OPA1	O60313-1.3	G930D	Pathogenic	0.99
OPA1	O60313-1.3	G930E	Pathogenic	0.997
OPA1	O60313-1.3	G930F	Pathogenic	0.997
OPA1	O60313-1.3	G930H	Pathogenic	0.998
OPA1	O60313-1.3	G930I	Pathogenic	0.999
OPA1	O60313-1.3	G930K	Pathogenic	0.995
OPA1	O60313-1.3	G930L	Pathogenic	0.999
OPA1	O60313-1.3	G930M	Pathogenic	0.998
OPA1	O60313-1.3	G930N	Pathogenic	0.976
OPA1	O60313-1.3	G930P	Pathogenic	0.997
OPA1	O60313-1.3	G930Q	Pathogenic	0.998
OPA1	O60313-1.3	G930R	Pathogenic	0.995
OPA1	O60313-1.3	G930S	Pathogenic	0.987
OPA1	O60313-1.3	G930T	Pathogenic	0.998
OPA1	O60313-1.3	G930V	Pathogenic	0.998
OPA1	O60313-1.3	G930W	Pathogenic	0.983
OPA1	O60313-1.3	G930Y	Pathogenic	0.998
OPA1	O60313-1.3	K931A	Neutral	0.437
OPA1	O60313-1.3	K931C	Pathogenic	0.791
OPA1	O60313-1.3	K931D	Pathogenic	0.695
OPA1	O60313-1.3	K931E	Neutral	0.204
OPA1	O60313-1.3	K931F	Pathogenic	0.684
OPA1	O60313-1.3	K931G	Pathogenic	0.735
OPA1	O60313-1.3	K931H	Pathogenic	0.525
OPA1	O60313-1.3	K931I	Pathogenic	0.673
OPA1	O60313-1.3	K931L	Neutral	0.438
OPA1	O60313-1.3	K931M	Neutral	0.292
OPA1	O60313-1.3	K931N	Neutral	0.407
OPA1	O60313-1.3	K931P	Neutral	0.367
OPA1	O60313-1.3	K931Q	Neutral	0.151
OPA1	O60313-1.3	K931R	Neutral	0.112
OPA1	O60313-1.3	K931S	Neutral	0.273
OPA1	O60313-1.3	K931T	Neutral	0.473
OPA1	O60313-1.3	K931V	Pathogenic	0.53
OPA1	O60313-1.3	K931W	Pathogenic	0.561
OPA1	O60313-1.3	K931Y	Pathogenic	0.61
OPA1	O60313-1.3	R932A	Pathogenic	0.969
OPA1	O60313-1.3	R932C	Pathogenic	0.993
OPA1	O60313-1.3	R932D	Pathogenic	0.996
OPA1	O60313-1.3	R932E	Pathogenic	0.967
OPA1	O60313-1.3	R932F	Pathogenic	0.989
OPA1	O60313-1.3	R932G	Pathogenic	0.991
OPA1	O60313-1.3	R932H	Pathogenic	0.938
OPA1	O60313-1.3	R932I	Pathogenic	0.988
OPA1	O60313-1.3	R932K	Pathogenic	0.843
OPA1	O60313-1.3	R932L	Pathogenic	0.969
OPA1	O60313-1.3	R932M	Pathogenic	0.942
OPA1	O60313-1.3	R932N	Pathogenic	0.965
OPA1	O60313-1.3	R932P	Pathogenic	0.985
OPA1	O60313-1.3	R932Q	Pathogenic	0.876
OPA1	O60313-1.3	R932S	Pathogenic	0.977
OPA1	O60313-1.3	R932T	Pathogenic	0.973
OPA1	O60313-1.3	R932V	Pathogenic	0.992
OPA1	O60313-1.3	R932W	Pathogenic	0.982
OPA1	O60313-1.3	R932Y	Pathogenic	0.985
OPA1	O60313-1.3	V933A	Pathogenic	0.952
OPA1	O60313-1.3	V933C	Pathogenic	0.991
OPA1	O60313-1.3	V933D	Pathogenic	0.995
OPA1	O60313-1.3	V933E	Pathogenic	0.988
OPA1	O60313-1.3	V933F	Pathogenic	0.988
OPA1	O60313-1.3	V933G	Pathogenic	0.997
OPA1	O60313-1.3	V933H	Pathogenic	0.998
OPA1	O60313-1.3	V933I	Pathogenic	0.543
OPA1	O60313-1.3	V933K	Pathogenic	0.981
OPA1	O60313-1.3	V933L	Pathogenic	0.916
OPA1	O60313-1.3	V933M	Pathogenic	0.944
OPA1	O60313-1.3	V933N	Pathogenic	0.996
OPA1	O60313-1.3	V933P	Pathogenic	0.996
OPA1	O60313-1.3	V933Q	Pathogenic	0.991
OPA1	O60313-1.3	V933R	Pathogenic	0.993
OPA1	O60313-1.3	V933S	Pathogenic	0.992
OPA1	O60313-1.3	V933T	Pathogenic	0.955
OPA1	O60313-1.3	V933W	Pathogenic	0.998
OPA1	O60313-1.3	V933Y	Pathogenic	0.991
OPA1	O60313-1.3	Q934A	Pathogenic	0.719
OPA1	O60313-1.3	Q934C	Pathogenic	0.926
OPA1	O60313-1.3	Q934D	Neutral	0.487
OPA1	O60313-1.3	Q934E	Neutral	0.12
OPA1	O60313-1.3	Q934F	Pathogenic	0.86
OPA1	O60313-1.3	Q934G	Pathogenic	0.902
OPA1	O60313-1.3	Q934H	Pathogenic	0.549
OPA1	O60313-1.3	Q934I	Pathogenic	0.863
OPA1	O60313-1.3	Q934K	Neutral	0.212
OPA1	O60313-1.3	Q934L	Pathogenic	0.704
OPA1	O60313-1.3	Q934M	Neutral	0.303
OPA1	O60313-1.3	Q934N	Pathogenic	0.53
OPA1	O60313-1.3	Q934P	Pathogenic	0.657
OPA1	O60313-1.3	Q934R	Neutral	0.202
OPA1	O60313-1.3	Q934S	Pathogenic	0.553
OPA1	O60313-1.3	Q934T	Pathogenic	0.747
OPA1	O60313-1.3	Q934V	Pathogenic	0.788
OPA1	O60313-1.3	Q934W	Pathogenic	0.555
OPA1	O60313-1.3	Q934Y	Pathogenic	0.603
OPA1	O60313-1.3	L935A	Pathogenic	0.966
OPA1	O60313-1.3	L935C	Pathogenic	0.983
OPA1	O60313-1.3	L935D	Pathogenic	0.996
OPA1	O60313-1.3	L935E	Pathogenic	0.992
OPA1	O60313-1.3	L935F	Pathogenic	0.975
OPA1	O60313-1.3	L935G	Pathogenic	0.998
OPA1	O60313-1.3	L935H	Pathogenic	0.996
OPA1	O60313-1.3	L935I	Pathogenic	0.825
OPA1	O60313-1.3	L935K	Pathogenic	0.968
OPA1	O60313-1.3	L935M	Pathogenic	0.771
OPA1	O60313-1.3	L935N	Pathogenic	0.991
OPA1	O60313-1.3	L935P	Pathogenic	0.997
OPA1	O60313-1.3	L935Q	Pathogenic	0.984
OPA1	O60313-1.3	L935R	Pathogenic	0.966
OPA1	O60313-1.3	L935S	Pathogenic	0.984
OPA1	O60313-1.3	L935T	Pathogenic	0.968
OPA1	O60313-1.3	L935V	Pathogenic	0.9
OPA1	O60313-1.3	L935W	Pathogenic	0.995
OPA1	O60313-1.3	L935Y	Pathogenic	0.984
OPA1	O60313-1.3	A936C	Pathogenic	0.965
OPA1	O60313-1.3	A936D	Pathogenic	0.994
OPA1	O60313-1.3	A936E	Pathogenic	0.983
OPA1	O60313-1.3	A936F	Pathogenic	0.989
OPA1	O60313-1.3	A936G	Pathogenic	0.975
OPA1	O60313-1.3	A936H	Pathogenic	0.997
OPA1	O60313-1.3	A936I	Pathogenic	0.971
OPA1	O60313-1.3	A936K	Pathogenic	0.974
OPA1	O60313-1.3	A936L	Pathogenic	0.973
OPA1	O60313-1.3	A936M	Pathogenic	0.982
OPA1	O60313-1.3	A936N	Pathogenic	0.995
OPA1	O60313-1.3	A936P	Pathogenic	0.99
OPA1	O60313-1.3	A936Q	Pathogenic	0.988
OPA1	O60313-1.3	A936R	Pathogenic	0.973
OPA1	O60313-1.3	A936S	Pathogenic	0.932
OPA1	O60313-1.3	A936T	Pathogenic	0.98
OPA1	O60313-1.3	A936V	Pathogenic	0.954
OPA1	O60313-1.3	A936W	Pathogenic	0.994
OPA1	O60313-1.3	A936Y	Pathogenic	0.995
OPA1	O60313-1.3	E937A	Pathogenic	0.98
OPA1	O60313-1.3	E937C	Pathogenic	0.999
OPA1	O60313-1.3	E937D	Pathogenic	0.822
OPA1	O60313-1.3	E937F	Pathogenic	0.991
OPA1	O60313-1.3	E937G	Pathogenic	0.994
OPA1	O60313-1.3	E937H	Pathogenic	0.957
OPA1	O60313-1.3	E937I	Pathogenic	0.991
OPA1	O60313-1.3	E937K	Pathogenic	0.914
OPA1	O60313-1.3	E937L	Pathogenic	0.992
OPA1	O60313-1.3	E937M	Pathogenic	0.985
OPA1	O60313-1.3	E937N	Pathogenic	0.977
OPA1	O60313-1.3	E937P	Pathogenic	0.973
OPA1	O60313-1.3	E937Q	Pathogenic	0.788
OPA1	O60313-1.3	E937R	Pathogenic	0.967
OPA1	O60313-1.3	E937S	Pathogenic	0.959
OPA1	O60313-1.3	E937T	Pathogenic	0.983
OPA1	O60313-1.3	E937V	Pathogenic	0.986
OPA1	O60313-1.3	E937W	Pathogenic	0.985
OPA1	O60313-1.3	E937Y	Pathogenic	0.988
OPA1	O60313-1.3	D938A	Pathogenic	0.894
OPA1	O60313-1.3	D938C	Pathogenic	0.934
OPA1	O60313-1.3	D938E	Neutral	0.225
OPA1	O60313-1.3	D938F	Pathogenic	0.854
OPA1	O60313-1.3	D938G	Pathogenic	0.783
OPA1	O60313-1.3	D938H	Pathogenic	0.772
OPA1	O60313-1.3	D938I	Pathogenic	0.858
OPA1	O60313-1.3	D938K	Pathogenic	0.856
OPA1	O60313-1.3	D938L	Pathogenic	0.95
OPA1	O60313-1.3	D938M	Pathogenic	0.91
OPA1	O60313-1.3	D938N	Neutral	0.461
OPA1	O60313-1.3	D938P	Pathogenic	0.686
OPA1	O60313-1.3	D938Q	Pathogenic	0.621
OPA1	O60313-1.3	D938R	Pathogenic	0.942
OPA1	O60313-1.3	D938S	Pathogenic	0.585
OPA1	O60313-1.3	D938T	Pathogenic	0.768
OPA1	O60313-1.3	D938V	Pathogenic	0.917
OPA1	O60313-1.3	D938W	Pathogenic	0.909
OPA1	O60313-1.3	D938Y	Pathogenic	0.924
OPA1	O60313-1.3	L939A	Pathogenic	0.966
OPA1	O60313-1.3	L939C	Pathogenic	0.983
OPA1	O60313-1.3	L939D	Pathogenic	0.996
OPA1	O60313-1.3	L939E	Pathogenic	0.992
OPA1	O60313-1.3	L939F	Pathogenic	0.975
OPA1	O60313-1.3	L939G	Pathogenic	0.998
OPA1	O60313-1.3	L939H	Pathogenic	0.996
OPA1	O60313-1.3	L939I	Pathogenic	0.825
OPA1	O60313-1.3	L939K	Pathogenic	0.968
OPA1	O60313-1.3	L939M	Pathogenic	0.771
OPA1	O60313-1.3	L939N	Pathogenic	0.991
OPA1	O60313-1.3	L939P	Pathogenic	0.997
OPA1	O60313-1.3	L939Q	Pathogenic	0.984
OPA1	O60313-1.3	L939R	Pathogenic	0.966
OPA1	O60313-1.3	L939S	Pathogenic	0.984
OPA1	O60313-1.3	L939T	Pathogenic	0.968
OPA1	O60313-1.3	L939V	Pathogenic	0.9
OPA1	O60313-1.3	L939W	Pathogenic	0.995
OPA1	O60313-1.3	L939Y	Pathogenic	0.984
OPA1	O60313-1.3	K940A	Pathogenic	0.525
OPA1	O60313-1.3	K940C	Pathogenic	0.843
OPA1	O60313-1.3	K940D	Pathogenic	0.764
OPA1	O60313-1.3	K940E	Neutral	0.268
OPA1	O60313-1.3	K940F	Pathogenic	0.756
OPA1	O60313-1.3	K940G	Pathogenic	0.798
OPA1	O60313-1.3	K940H	Pathogenic	0.611
OPA1	O60313-1.3	K940I	Pathogenic	0.745
OPA1	O60313-1.3	K940L	Pathogenic	0.526
OPA1	O60313-1.3	K940M	Neutral	0.37
OPA1	O60313-1.3	K940N	Neutral	0.494
OPA1	O60313-1.3	K940P	Neutral	0.453
OPA1	O60313-1.3	K940Q	Neutral	0.203
OPA1	O60313-1.3	K940R	Neutral	0.153
OPA1	O60313-1.3	K940S	Neutral	0.349
OPA1	O60313-1.3	K940T	Pathogenic	0.561
OPA1	O60313-1.3	K940V	Pathogenic	0.617
OPA1	O60313-1.3	K940W	Pathogenic	0.646
OPA1	O60313-1.3	K940Y	Pathogenic	0.69
OPA1	O60313-1.3	K941A	Neutral	0.224
OPA1	O60313-1.3	K941C	Pathogenic	0.585
OPA1	O60313-1.3	K941D	Neutral	0.459
OPA1	O60313-1.3	K941E	Neutral	0.087
OPA1	O60313-1.3	K941F	Neutral	0.447
OPA1	O60313-1.3	K941G	Pathogenic	0.509
OPA1	O60313-1.3	K941H	Neutral	0.291
OPA1	O60313-1.3	K941I	Neutral	0.434
OPA1	O60313-1.3	K941L	Neutral	0.225
OPA1	O60313-1.3	K941M	Neutral	0.133
OPA1	O60313-1.3	K941N	Neutral	0.204
OPA1	O60313-1.3	K941P	Neutral	0.178
OPA1	O60313-1.3	K941Q	Neutral	0.062
OPA1	O60313-1.3	K941R	Neutral	0.045
OPA1	O60313-1.3	K941S	Neutral	0.123
OPA1	O60313-1.3	K941T	Neutral	0.25
OPA1	O60313-1.3	K941V	Neutral	0.296
OPA1	O60313-1.3	K941W	Neutral	0.323
OPA1	O60313-1.3	K941Y	Neutral	0.368
OPA1	O60313-1.3	V942A	Neutral	0.491
OPA1	O60313-1.3	V942C	Pathogenic	0.848
OPA1	O60313-1.3	V942D	Pathogenic	0.906
OPA1	O60313-1.3	V942E	Pathogenic	0.795
OPA1	O60313-1.3	V942F	Pathogenic	0.797
OPA1	O60313-1.3	V942G	Pathogenic	0.943
OPA1	O60313-1.3	V942H	Pathogenic	0.956
OPA1	O60313-1.3	V942I	Neutral	0.054
OPA1	O60313-1.3	V942K	Pathogenic	0.718
OPA1	O60313-1.3	V942L	Neutral	0.345
OPA1	O60313-1.3	V942M	Neutral	0.448
OPA1	O60313-1.3	V942N	Pathogenic	0.919
OPA1	O60313-1.3	V942P	Pathogenic	0.928
OPA1	O60313-1.3	V942Q	Pathogenic	0.848
OPA1	O60313-1.3	V942R	Pathogenic	0.874
OPA1	O60313-1.3	V942S	Pathogenic	0.858
OPA1	O60313-1.3	V942T	Pathogenic	0.504
OPA1	O60313-1.3	V942W	Pathogenic	0.951
OPA1	O60313-1.3	V942Y	Pathogenic	0.837
OPA1	O60313-1.3	R943A	Pathogenic	0.869
OPA1	O60313-1.3	R943C	Pathogenic	0.97
OPA1	O60313-1.3	R943D	Pathogenic	0.983
OPA1	O60313-1.3	R943E	Pathogenic	0.864
OPA1	O60313-1.3	R943F	Pathogenic	0.949
OPA1	O60313-1.3	R943G	Pathogenic	0.96
OPA1	O60313-1.3	R943H	Pathogenic	0.765
OPA1	O60313-1.3	R943I	Pathogenic	0.946
OPA1	O60313-1.3	R943K	Pathogenic	0.535
OPA1	O60313-1.3	R943L	Pathogenic	0.869
OPA1	O60313-1.3	R943M	Pathogenic	0.779
OPA1	O60313-1.3	R943N	Pathogenic	0.854
OPA1	O60313-1.3	R943P	Pathogenic	0.935
OPA1	O60313-1.3	R943Q	Pathogenic	0.604
OPA1	O60313-1.3	R943S	Pathogenic	0.903
OPA1	O60313-1.3	R943T	Pathogenic	0.884
OPA1	O60313-1.3	R943V	Pathogenic	0.965
OPA1	O60313-1.3	R943W	Pathogenic	0.923
OPA1	O60313-1.3	R943Y	Pathogenic	0.933
OPA1	O60313-1.3	E944A	Neutral	0.076
OPA1	O60313-1.3	E944C	Pathogenic	0.535
OPA1	O60313-1.3	E944D	Neutral	0.008
OPA1	O60313-1.3	E944F	Neutral	0.158
OPA1	O60313-1.3	E944G	Neutral	0.226
OPA1	O60313-1.3	E944H	Neutral	0.036
OPA1	O60313-1.3	E944I	Neutral	0.162
OPA1	O60313-1.3	E944K	Neutral	0.017
OPA1	O60313-1.3	E944L	Neutral	0.175
OPA1	O60313-1.3	E944M	Neutral	0.101
OPA1	O60313-1.3	E944N	Neutral	0.067
OPA1	O60313-1.3	E944P	Neutral	0.058
OPA1	O60313-1.3	E944Q	Neutral	0.006
OPA1	O60313-1.3	E944R	Neutral	0.046
OPA1	O60313-1.3	E944S	Neutral	0.038
OPA1	O60313-1.3	E944T	Neutral	0.086
OPA1	O60313-1.3	E944V	Neutral	0.106
OPA1	O60313-1.3	E944W	Neutral	0.1
OPA1	O60313-1.3	E944Y	Neutral	0.119
OPA1	O60313-1.3	I945A	Pathogenic	0.604
OPA1	O60313-1.3	I945C	Pathogenic	0.753
OPA1	O60313-1.3	I945D	Pathogenic	0.84
OPA1	O60313-1.3	I945E	Pathogenic	0.863
OPA1	O60313-1.3	I945F	Pathogenic	0.708
OPA1	O60313-1.3	I945G	Pathogenic	0.963
OPA1	O60313-1.3	I945H	Pathogenic	0.93
OPA1	O60313-1.3	I945K	Pathogenic	0.823
OPA1	O60313-1.3	I945L	Neutral	0.217
OPA1	O60313-1.3	I945M	Neutral	0.344
OPA1	O60313-1.3	I945N	Pathogenic	0.862
OPA1	O60313-1.3	I945P	Pathogenic	0.953
OPA1	O60313-1.3	I945Q	Pathogenic	0.904
OPA1	O60313-1.3	I945R	Pathogenic	0.814
OPA1	O60313-1.3	I945S	Pathogenic	0.768
OPA1	O60313-1.3	I945T	Pathogenic	0.616
OPA1	O60313-1.3	I945V	Neutral	0.054
OPA1	O60313-1.3	I945W	Pathogenic	0.973
OPA1	O60313-1.3	I945Y	Pathogenic	0.763
OPA1	O60313-1.3	Q946A	Pathogenic	0.856
OPA1	O60313-1.3	Q946C	Pathogenic	0.967
OPA1	O60313-1.3	Q946D	Pathogenic	0.688
OPA1	O60313-1.3	Q946E	Neutral	0.24
OPA1	O60313-1.3	Q946F	Pathogenic	0.934
OPA1	O60313-1.3	Q946G	Pathogenic	0.955
OPA1	O60313-1.3	Q946H	Pathogenic	0.739
OPA1	O60313-1.3	Q946I	Pathogenic	0.936
OPA1	O60313-1.3	Q946K	Neutral	0.385
OPA1	O60313-1.3	Q946L	Pathogenic	0.847
OPA1	O60313-1.3	Q946M	Pathogenic	0.503
OPA1	O60313-1.3	Q946N	Pathogenic	0.723
OPA1	O60313-1.3	Q946P	Pathogenic	0.817
OPA1	O60313-1.3	Q946R	Neutral	0.37
OPA1	O60313-1.3	Q946S	Pathogenic	0.742
OPA1	O60313-1.3	Q946T	Pathogenic	0.873
OPA1	O60313-1.3	Q946V	Pathogenic	0.896
OPA1	O60313-1.3	Q946W	Pathogenic	0.743
OPA1	O60313-1.3	Q946Y	Pathogenic	0.779
OPA1	O60313-1.3	E947A	Pathogenic	0.705
OPA1	O60313-1.3	E947C	Pathogenic	0.971
OPA1	O60313-1.3	E947D	Neutral	0.184
OPA1	O60313-1.3	E947F	Pathogenic	0.846
OPA1	O60313-1.3	E947G	Pathogenic	0.895
OPA1	O60313-1.3	E947H	Pathogenic	0.522
OPA1	O60313-1.3	E947I	Pathogenic	0.849
OPA1	O60313-1.3	E947K	Neutral	0.342
OPA1	O60313-1.3	E947L	Pathogenic	0.861
OPA1	O60313-1.3	E947M	Pathogenic	0.767
OPA1	O60313-1.3	E947N	Pathogenic	0.678
OPA1	O60313-1.3	E947P	Pathogenic	0.641
OPA1	O60313-1.3	E947Q	Neutral	0.154
OPA1	O60313-1.3	E947R	Pathogenic	0.586
OPA1	O60313-1.3	E947S	Pathogenic	0.536
OPA1	O60313-1.3	E947T	Pathogenic	0.734
OPA1	O60313-1.3	E947V	Pathogenic	0.776
OPA1	O60313-1.3	E947W	Pathogenic	0.764
OPA1	O60313-1.3	E947Y	Pathogenic	0.798
OPA1	O60313-1.3	K948A	Pathogenic	0.677
OPA1	O60313-1.3	K948C	Pathogenic	0.911
OPA1	O60313-1.3	K948D	Pathogenic	0.86
OPA1	O60313-1.3	K948E	Neutral	0.409
OPA1	O60313-1.3	K948F	Pathogenic	0.854
OPA1	O60313-1.3	K948G	Pathogenic	0.882
OPA1	O60313-1.3	K948H	Pathogenic	0.748
OPA1	O60313-1.3	K948I	Pathogenic	0.847
OPA1	O60313-1.3	K948L	Pathogenic	0.677
OPA1	O60313-1.3	K948M	Pathogenic	0.526
OPA1	O60313-1.3	K948N	Pathogenic	0.649
OPA1	O60313-1.3	K948P	Pathogenic	0.61
OPA1	O60313-1.3	K948Q	Neutral	0.325
OPA1	O60313-1.3	K948R	Neutral	0.254
OPA1	O60313-1.3	K948S	Pathogenic	0.503
OPA1	O60313-1.3	K948T	Pathogenic	0.707
OPA1	O60313-1.3	K948V	Pathogenic	0.753
OPA1	O60313-1.3	K948W	Pathogenic	0.775
OPA1	O60313-1.3	K948Y	Pathogenic	0.808
OPA1	O60313-1.3	L949A	Pathogenic	0.631
OPA1	O60313-1.3	L949C	Pathogenic	0.773
OPA1	O60313-1.3	L949D	Pathogenic	0.944
OPA1	O60313-1.3	L949E	Pathogenic	0.876
OPA1	O60313-1.3	L949F	Pathogenic	0.698
OPA1	O60313-1.3	L949G	Pathogenic	0.967
OPA1	O60313-1.3	L949H	Pathogenic	0.937
OPA1	O60313-1.3	L949I	Neutral	0.22
OPA1	O60313-1.3	L949K	Pathogenic	0.642
OPA1	O60313-1.3	L949M	Neutral	0.168
OPA1	O60313-1.3	L949N	Pathogenic	0.874
OPA1	O60313-1.3	L949P	Pathogenic	0.958
OPA1	O60313-1.3	L949Q	Pathogenic	0.785
OPA1	O60313-1.3	L949R	Pathogenic	0.628
OPA1	O60313-1.3	L949S	Pathogenic	0.787
OPA1	O60313-1.3	L949T	Pathogenic	0.642
OPA1	O60313-1.3	L949V	Neutral	0.35
OPA1	O60313-1.3	L949W	Pathogenic	0.92
OPA1	O60313-1.3	L949Y	Pathogenic	0.783
OPA1	O60313-1.3	D950A	Neutral	0.177
OPA1	O60313-1.3	D950C	Neutral	0.266
OPA1	O60313-1.3	D950E	Neutral	0.007
OPA1	O60313-1.3	D950F	Neutral	0.13
OPA1	O60313-1.3	D950G	Neutral	0.084
OPA1	O60313-1.3	D950H	Neutral	0.08
OPA1	O60313-1.3	D950I	Neutral	0.133
OPA1	O60313-1.3	D950K	Neutral	0.131
OPA1	O60313-1.3	D950L	Neutral	0.329
OPA1	O60313-1.3	D950M	Neutral	0.206
OPA1	O60313-1.3	D950N	Neutral	0.021
OPA1	O60313-1.3	D950P	Neutral	0.053
OPA1	O60313-1.3	D950Q	Neutral	0.04
OPA1	O60313-1.3	D950R	Neutral	0.292
OPA1	O60313-1.3	D950S	Neutral	0.035
OPA1	O60313-1.3	D950T	Neutral	0.078
OPA1	O60313-1.3	D950V	Neutral	0.22
OPA1	O60313-1.3	D950W	Neutral	0.204
OPA1	O60313-1.3	D950Y	Neutral	0.238
OPA1	O60313-1.3	A951C	Neutral	0.048
OPA1	O60313-1.3	A951D	Neutral	0.223
OPA1	O60313-1.3	A951E	Neutral	0.095
OPA1	O60313-1.3	A951F	Neutral	0.144
OPA1	O60313-1.3	A951G	Neutral	0.066
OPA1	O60313-1.3	A951H	Neutral	0.372
OPA1	O60313-1.3	A951I	Neutral	0.056
OPA1	O60313-1.3	A951K	Neutral	0.064
OPA1	O60313-1.3	A951L	Neutral	0.062
OPA1	O60313-1.3	A951M	Neutral	0.092
OPA1	O60313-1.3	A951N	Neutral	0.247
OPA1	O60313-1.3	A951P	Neutral	0.155
OPA1	O60313-1.3	A951Q	Neutral	0.131
OPA1	O60313-1.3	A951R	Neutral	0.061
OPA1	O60313-1.3	A951S	Neutral	0.024
OPA1	O60313-1.3	A951T	Neutral	0.08
OPA1	O60313-1.3	A951V	Neutral	0.036
OPA1	O60313-1.3	A951W	Neutral	0.224
OPA1	O60313-1.3	A951Y	Neutral	0.26
OPA1	O60313-1.3	F952A	Pathogenic	0.907
OPA1	O60313-1.3	F952C	Pathogenic	0.951
OPA1	O60313-1.3	F952D	Pathogenic	0.92
OPA1	O60313-1.3	F952E	Pathogenic	0.933
OPA1	O60313-1.3	F952G	Pathogenic	0.952
OPA1	O60313-1.3	F952H	Pathogenic	0.776
OPA1	O60313-1.3	F952I	Pathogenic	0.846
OPA1	O60313-1.3	F952K	Pathogenic	0.917
OPA1	O60313-1.3	F952L	Pathogenic	0.837
OPA1	O60313-1.3	F952M	Pathogenic	0.77
OPA1	O60313-1.3	F952N	Pathogenic	0.932
OPA1	O60313-1.3	F952P	Pathogenic	0.992
OPA1	O60313-1.3	F952Q	Pathogenic	0.954
OPA1	O60313-1.3	F952R	Pathogenic	0.913
OPA1	O60313-1.3	F952S	Pathogenic	0.879
OPA1	O60313-1.3	F952T	Pathogenic	0.911
OPA1	O60313-1.3	F952V	Pathogenic	0.899
OPA1	O60313-1.3	F952W	Pathogenic	0.541
OPA1	O60313-1.3	F952Y	Neutral	0.098
OPA1	O60313-1.3	I953A	Pathogenic	0.633
OPA1	O60313-1.3	I953C	Pathogenic	0.774
OPA1	O60313-1.3	I953D	Pathogenic	0.855
OPA1	O60313-1.3	I953E	Pathogenic	0.877
OPA1	O60313-1.3	I953F	Pathogenic	0.733
OPA1	O60313-1.3	I953G	Pathogenic	0.967
OPA1	O60313-1.3	I953H	Pathogenic	0.937
OPA1	O60313-1.3	I953K	Pathogenic	0.84
OPA1	O60313-1.3	I953L	Neutral	0.239
OPA1	O60313-1.3	I953M	Neutral	0.372
OPA1	O60313-1.3	I953N	Pathogenic	0.876
OPA1	O60313-1.3	I953P	Pathogenic	0.958
OPA1	O60313-1.3	I953Q	Pathogenic	0.914
OPA1	O60313-1.3	I953R	Pathogenic	0.832
OPA1	O60313-1.3	I953S	Pathogenic	0.789
OPA1	O60313-1.3	I953T	Pathogenic	0.645
OPA1	O60313-1.3	I953V	Neutral	0.061
OPA1	O60313-1.3	I953W	Pathogenic	0.976
OPA1	O60313-1.3	I953Y	Pathogenic	0.785
OPA1	O60313-1.3	E954A	Neutral	0.076
OPA1	O60313-1.3	E954C	Pathogenic	0.538
OPA1	O60313-1.3	E954D	Neutral	0.008
OPA1	O60313-1.3	E954F	Neutral	0.16
OPA1	O60313-1.3	E954G	Neutral	0.228
OPA1	O60313-1.3	E954H	Neutral	0.036
OPA1	O60313-1.3	E954I	Neutral	0.163
OPA1	O60313-1.3	E954K	Neutral	0.018
OPA1	O60313-1.3	E954L	Neutral	0.177
OPA1	O60313-1.3	E954M	Neutral	0.102
OPA1	O60313-1.3	E954N	Neutral	0.068
OPA1	O60313-1.3	E954P	Neutral	0.058
OPA1	O60313-1.3	E954Q	Neutral	0.006
OPA1	O60313-1.3	E954R	Neutral	0.047
OPA1	O60313-1.3	E954S	Neutral	0.038
OPA1	O60313-1.3	E954T	Neutral	0.087
OPA1	O60313-1.3	E954V	Neutral	0.107
OPA1	O60313-1.3	E954W	Neutral	0.101
OPA1	O60313-1.3	E954Y	Neutral	0.12
OPA1	O60313-1.3	A955C	Neutral	0.481
OPA1	O60313-1.3	A955D	Pathogenic	0.841
OPA1	O60313-1.3	A955E	Pathogenic	0.658
OPA1	O60313-1.3	A955F	Pathogenic	0.756
OPA1	O60313-1.3	A955G	Pathogenic	0.565
OPA1	O60313-1.3	A955H	Pathogenic	0.916
OPA1	O60313-1.3	A955I	Pathogenic	0.524
OPA1	O60313-1.3	A955K	Pathogenic	0.559
OPA1	O60313-1.3	A955L	Pathogenic	0.547
OPA1	O60313-1.3	A955M	Pathogenic	0.65
OPA1	O60313-1.3	A955N	Pathogenic	0.858
OPA1	O60313-1.3	A955P	Pathogenic	0.771
OPA1	O60313-1.3	A955Q	Pathogenic	0.735
OPA1	O60313-1.3	A955R	Pathogenic	0.543
OPA1	O60313-1.3	A955S	Neutral	0.312
OPA1	O60313-1.3	A955T	Pathogenic	0.615
OPA1	O60313-1.3	A955V	Neutral	0.411
OPA1	O60313-1.3	A955W	Pathogenic	0.842
OPA1	O60313-1.3	A955Y	Pathogenic	0.866
OPA1	O60313-1.3	L956A	Pathogenic	0.724
OPA1	O60313-1.3	L956C	Pathogenic	0.839
OPA1	O60313-1.3	L956D	Pathogenic	0.963
OPA1	O60313-1.3	L956E	Pathogenic	0.916
OPA1	O60313-1.3	L956F	Pathogenic	0.78
OPA1	O60313-1.3	L956G	Pathogenic	0.978
OPA1	O60313-1.3	L956H	Pathogenic	0.958
OPA1	O60313-1.3	L956I	Neutral	0.303
OPA1	O60313-1.3	L956K	Pathogenic	0.734
OPA1	O60313-1.3	L956M	Neutral	0.237
OPA1	O60313-1.3	L956N	Pathogenic	0.915
OPA1	O60313-1.3	L956P	Pathogenic	0.972
OPA1	O60313-1.3	L956Q	Pathogenic	0.848
OPA1	O60313-1.3	L956R	Pathogenic	0.721
OPA1	O60313-1.3	L956S	Pathogenic	0.85
OPA1	O60313-1.3	L956T	Pathogenic	0.734
OPA1	O60313-1.3	L956V	Neutral	0.453
OPA1	O60313-1.3	L956W	Pathogenic	0.946
OPA1	O60313-1.3	L956Y	Pathogenic	0.847
OPA1	O60313-1.3	H957A	Pathogenic	0.591
OPA1	O60313-1.3	H957C	Pathogenic	0.708
OPA1	O60313-1.3	H957D	Neutral	0.219
OPA1	O60313-1.3	H957E	Neutral	0.104
OPA1	O60313-1.3	H957F	Neutral	0.127
OPA1	O60313-1.3	H957G	Pathogenic	0.583
OPA1	O60313-1.3	H957I	Pathogenic	0.557
OPA1	O60313-1.3	H957K	Neutral	0.192
OPA1	O60313-1.3	H957L	Pathogenic	0.58
OPA1	O60313-1.3	H957M	Neutral	0.423
OPA1	O60313-1.3	H957N	Neutral	0.038
OPA1	O60313-1.3	H957P	Pathogenic	0.519
OPA1	O60313-1.3	H957Q	Neutral	0.148
OPA1	O60313-1.3	H957R	Neutral	0.072
OPA1	O60313-1.3	H957S	Neutral	0.339
OPA1	O60313-1.3	H957T	Pathogenic	0.625
OPA1	O60313-1.3	H957V	Pathogenic	0.677
OPA1	O60313-1.3	H957W	Neutral	0.199
OPA1	O60313-1.3	H957Y	Neutral	0.012
OPA1	O60313-1.3	Q958A	Neutral	0.053
OPA1	O60313-1.3	Q958C	Neutral	0.214
OPA1	O60313-1.3	Q958D	Neutral	0.02
OPA1	O60313-1.3	Q958E	Neutral	0.003
OPA1	O60313-1.3	Q958F	Neutral	0.118
OPA1	O60313-1.3	Q958G	Neutral	0.166
OPA1	O60313-1.3	Q958H	Neutral	0.026
OPA1	O60313-1.3	Q958I	Neutral	0.12
OPA1	O60313-1.3	Q958K	Neutral	0.006
OPA1	O60313-1.3	Q958L	Neutral	0.049
OPA1	O60313-1.3	Q958M	Neutral	0.009
OPA1	O60313-1.3	Q958N	Neutral	0.024
OPA1	O60313-1.3	Q958P	Neutral	0.04
OPA1	O60313-1.3	Q958R	Neutral	0.005
OPA1	O60313-1.3	Q958S	Neutral	0.026
OPA1	O60313-1.3	Q958T	Neutral	0.061
OPA1	O60313-1.3	Q958V	Neutral	0.075
OPA1	O60313-1.3	Q958W	Neutral	0.026
OPA1	O60313-1.3	Q958Y	Neutral	0.032
OPA1	O60313-1.3	E959A	Pathogenic	0.651
OPA1	O60313-1.3	E959C	Pathogenic	0.963
OPA1	O60313-1.3	E959D	Neutral	0.15
OPA1	O60313-1.3	E959F	Pathogenic	0.811
OPA1	O60313-1.3	E959G	Pathogenic	0.87
OPA1	O60313-1.3	E959H	Neutral	0.461
OPA1	O60313-1.3	E959I	Pathogenic	0.816
OPA1	O60313-1.3	E959K	Neutral	0.289
OPA1	O60313-1.3	E959L	Pathogenic	0.829
OPA1	O60313-1.3	E959M	Pathogenic	0.72
OPA1	O60313-1.3	E959N	Pathogenic	0.623
OPA1	O60313-1.3	E959P	Pathogenic	0.583
OPA1	O60313-1.3	E959Q	Neutral	0.125
OPA1	O60313-1.3	E959R	Pathogenic	0.526
OPA1	O60313-1.3	E959S	Neutral	0.475
OPA1	O60313-1.3	E959T	Pathogenic	0.683
OPA1	O60313-1.3	E959V	Pathogenic	0.731
OPA1	O60313-1.3	E959W	Pathogenic	0.717
OPA1	O60313-1.3	E959Y	Pathogenic	0.756
OPA1	O60313-1.3	K960A	Pathogenic	0.504
OPA1	O60313-1.3	K960C	Pathogenic	0.832
OPA1	O60313-1.3	K960D	Pathogenic	0.749
OPA1	O60313-1.3	K960E	Neutral	0.252
OPA1	O60313-1.3	K960F	Pathogenic	0.74
OPA1	O60313-1.3	K960G	Pathogenic	0.785
OPA1	O60313-1.3	K960H	Pathogenic	0.591
OPA1	O60313-1.3	K960I	Pathogenic	0.729
OPA1	O60313-1.3	K960L	Pathogenic	0.505
OPA1	O60313-1.3	K960M	Neutral	0.351
OPA1	O60313-1.3	K960N	Neutral	0.473
OPA1	O60313-1.3	K960P	Neutral	0.432
OPA1	O60313-1.3	K960Q	Neutral	0.19
OPA1	O60313-1.3	K960R	Neutral	0.142
OPA1	O60313-1.3	K960S	Neutral	0.33
OPA1	O60313-1.3	K960T	Pathogenic	0.54
OPA1	O60313-1.3	K960V	Pathogenic	0.597
OPA1	O60313-1.3	K960W	Pathogenic	0.627
OPA1	O60313-1.3	K960Y	Pathogenic	0.672
NPHS1	O60500-1.1	M1A	Neutral	0.037
NPHS1	O60500-1.1	M1C	Neutral	0.009
NPHS1	O60500-1.1	M1D	Neutral	0.047
NPHS1	O60500-1.1	M1E	Neutral	0.038
NPHS1	O60500-1.1	M1F	Neutral	0.011
NPHS1	O60500-1.1	M1G	Neutral	0.042
NPHS1	O60500-1.1	M1H	Neutral	0.01
NPHS1	O60500-1.1	M1I	Neutral	0.013
NPHS1	O60500-1.1	M1K	Neutral	0.083
NPHS1	O60500-1.1	M1L	Neutral	0.017
NPHS1	O60500-1.1	M1N	Neutral	0.048
NPHS1	O60500-1.1	M1P	Neutral	0.008
NPHS1	O60500-1.1	M1Q	Neutral	0.04
NPHS1	O60500-1.1	M1R	Neutral	0.112
NPHS1	O60500-1.1	M1S	Neutral	0.053
NPHS1	O60500-1.1	M1T	Neutral	0.022
NPHS1	O60500-1.1	M1V	Neutral	0.009
NPHS1	O60500-1.1	M1W	Neutral	0.029
NPHS1	O60500-1.1	M1Y	Neutral	0.006
NPHS1	O60500-1.1	A2C	Neutral	0.001
NPHS1	O60500-1.1	A2D	Neutral	0.001
NPHS1	O60500-1.1	A2E	Neutral	0.002
NPHS1	O60500-1.1	A2F	Neutral	0.005
NPHS1	O60500-1.1	A2G	Neutral	0.001
NPHS1	O60500-1.1	A2H	Neutral	0.0
NPHS1	O60500-1.1	A2I	Neutral	0.005
NPHS1	O60500-1.1	A2K	Neutral	0.005
NPHS1	O60500-1.1	A2L	Neutral	0.005
NPHS1	O60500-1.1	A2M	Neutral	0.002
NPHS1	O60500-1.1	A2N	Neutral	0.001
NPHS1	O60500-1.1	A2P	Neutral	0.0
NPHS1	O60500-1.1	A2Q	Neutral	0.001
NPHS1	O60500-1.1	A2R	Neutral	0.007
NPHS1	O60500-1.1	A2S	Neutral	0.001
NPHS1	O60500-1.1	A2T	Neutral	0.0
NPHS1	O60500-1.1	A2V	Neutral	0.002
NPHS1	O60500-1.1	A2W	Neutral	0.012
NPHS1	O60500-1.1	A2Y	Neutral	0.002
NPHS1	O60500-1.1	L3A	Neutral	0.013
NPHS1	O60500-1.1	L3C	Neutral	0.003
NPHS1	O60500-1.1	L3D	Neutral	0.011
NPHS1	O60500-1.1	L3E	Neutral	0.009
NPHS1	O60500-1.1	L3F	Neutral	0.001
NPHS1	O60500-1.1	L3G	Neutral	0.01
NPHS1	O60500-1.1	L3H	Neutral	0.002
NPHS1	O60500-1.1	L3I	Neutral	0.002
NPHS1	O60500-1.1	L3K	Neutral	0.02
NPHS1	O60500-1.1	L3M	Neutral	0.003
NPHS1	O60500-1.1	L3N	Neutral	0.011
NPHS1	O60500-1.1	L3P	Neutral	0.002
NPHS1	O60500-1.1	L3Q	Neutral	0.006
NPHS1	O60500-1.1	L3R	Neutral	0.027
NPHS1	O60500-1.1	L3S	Neutral	0.013
NPHS1	O60500-1.1	L3T	Neutral	0.008
NPHS1	O60500-1.1	L3V	Neutral	0.003
NPHS1	O60500-1.1	L3W	Neutral	0.002
NPHS1	O60500-1.1	L3Y	Neutral	0.002
NPHS1	O60500-1.1	G4A	Neutral	0.0
NPHS1	O60500-1.1	G4C	Neutral	0.0
NPHS1	O60500-1.1	G4D	Neutral	0.0
NPHS1	O60500-1.1	G4E	Neutral	0.0
NPHS1	O60500-1.1	G4F	Neutral	0.001
NPHS1	O60500-1.1	G4H	Neutral	0.0
NPHS1	O60500-1.1	G4I	Neutral	0.001
NPHS1	O60500-1.1	G4K	Neutral	0.0
NPHS1	O60500-1.1	G4L	Neutral	0.0
NPHS1	O60500-1.1	G4M	Neutral	0.0
NPHS1	O60500-1.1	G4N	Neutral	0.0
NPHS1	O60500-1.1	G4P	Neutral	0.0
NPHS1	O60500-1.1	G4Q	Neutral	0.0
NPHS1	O60500-1.1	G4R	Neutral	0.001
NPHS1	O60500-1.1	G4S	Neutral	0.0
NPHS1	O60500-1.1	G4T	Neutral	0.0
NPHS1	O60500-1.1	G4V	Neutral	0.0
NPHS1	O60500-1.1	G4W	Neutral	0.006
NPHS1	O60500-1.1	G4Y	Neutral	0.0
NPHS1	O60500-1.1	T5A	Neutral	0.0
NPHS1	O60500-1.1	T5C	Neutral	0.001
NPHS1	O60500-1.1	T5D	Neutral	0.001
NPHS1	O60500-1.1	T5E	Neutral	0.001
NPHS1	O60500-1.1	T5F	Neutral	0.003
NPHS1	O60500-1.1	T5G	Neutral	0.0
NPHS1	O60500-1.1	T5H	Neutral	0.0
NPHS1	O60500-1.1	T5I	Neutral	0.003
NPHS1	O60500-1.1	T5K	Neutral	0.003
NPHS1	O60500-1.1	T5L	Neutral	0.003
NPHS1	O60500-1.1	T5M	Neutral	0.001
NPHS1	O60500-1.1	T5N	Neutral	0.001
NPHS1	O60500-1.1	T5P	Neutral	0.0
NPHS1	O60500-1.1	T5Q	Neutral	0.001
NPHS1	O60500-1.1	T5R	Neutral	0.004
NPHS1	O60500-1.1	T5S	Neutral	0.001
NPHS1	O60500-1.1	T5V	Neutral	0.001
NPHS1	O60500-1.1	T5W	Neutral	0.011
NPHS1	O60500-1.1	T5Y	Neutral	0.001
NPHS1	O60500-1.1	T6A	Neutral	0.0
NPHS1	O60500-1.1	T6C	Neutral	0.0
NPHS1	O60500-1.1	T6D	Neutral	0.0
NPHS1	O60500-1.1	T6E	Neutral	0.0
NPHS1	O60500-1.1	T6F	Neutral	0.0
NPHS1	O60500-1.1	T6G	Neutral	0.0
NPHS1	O60500-1.1	T6H	Neutral	0.0
NPHS1	O60500-1.1	T6I	Neutral	0.0
NPHS1	O60500-1.1	T6K	Neutral	0.0
NPHS1	O60500-1.1	T6L	Neutral	0.0
NPHS1	O60500-1.1	T6M	Neutral	0.0
NPHS1	O60500-1.1	T6N	Neutral	0.0
NPHS1	O60500-1.1	T6P	Neutral	0.0
NPHS1	O60500-1.1	T6Q	Neutral	0.0
NPHS1	O60500-1.1	T6R	Neutral	0.0
NPHS1	O60500-1.1	T6S	Neutral	0.0
NPHS1	O60500-1.1	T6V	Neutral	0.0
NPHS1	O60500-1.1	T6W	Neutral	0.0
NPHS1	O60500-1.1	T6Y	Neutral	0.0
NPHS1	O60500-1.1	L7A	Neutral	0.0
NPHS1	O60500-1.1	L7C	Neutral	0.0
NPHS1	O60500-1.1	L7D	Neutral	0.0
NPHS1	O60500-1.1	L7E	Neutral	0.0
NPHS1	O60500-1.1	L7F	Neutral	0.0
NPHS1	O60500-1.1	L7G	Neutral	0.0
NPHS1	O60500-1.1	L7H	Neutral	0.0
NPHS1	O60500-1.1	L7I	Neutral	0.0
NPHS1	O60500-1.1	L7K	Neutral	0.0
NPHS1	O60500-1.1	L7M	Neutral	0.0
NPHS1	O60500-1.1	L7N	Neutral	0.0
NPHS1	O60500-1.1	L7P	Neutral	0.0
NPHS1	O60500-1.1	L7Q	Neutral	0.0
NPHS1	O60500-1.1	L7R	Neutral	0.0
NPHS1	O60500-1.1	L7S	Neutral	0.0
NPHS1	O60500-1.1	L7T	Neutral	0.0
NPHS1	O60500-1.1	L7V	Neutral	0.0
NPHS1	O60500-1.1	L7W	Neutral	0.0
NPHS1	O60500-1.1	L7Y	Neutral	0.0
NPHS1	O60500-1.1	R8A	Neutral	0.001
NPHS1	O60500-1.1	R8C	Neutral	0.001
NPHS1	O60500-1.1	R8D	Neutral	0.0
NPHS1	O60500-1.1	R8E	Neutral	0.0
NPHS1	O60500-1.1	R8F	Neutral	0.001
NPHS1	O60500-1.1	R8G	Neutral	0.0
NPHS1	O60500-1.1	R8H	Neutral	0.0
NPHS1	O60500-1.1	R8I	Neutral	0.001
NPHS1	O60500-1.1	R8K	Neutral	0.0
NPHS1	O60500-1.1	R8L	Neutral	0.001
NPHS1	O60500-1.1	R8M	Neutral	0.001
NPHS1	O60500-1.1	R8N	Neutral	0.0
NPHS1	O60500-1.1	R8P	Neutral	0.001
NPHS1	O60500-1.1	R8Q	Neutral	0.0
NPHS1	O60500-1.1	R8S	Neutral	0.0
NPHS1	O60500-1.1	R8T	Neutral	0.0
NPHS1	O60500-1.1	R8V	Neutral	0.001
NPHS1	O60500-1.1	R8W	Neutral	0.001
NPHS1	O60500-1.1	R8Y	Neutral	0.0
NPHS1	O60500-1.1	A9C	Neutral	0.0
NPHS1	O60500-1.1	A9D	Neutral	0.0
NPHS1	O60500-1.1	A9E	Neutral	0.0
NPHS1	O60500-1.1	A9F	Neutral	0.001
NPHS1	O60500-1.1	A9G	Neutral	0.0
NPHS1	O60500-1.1	A9H	Neutral	0.0
NPHS1	O60500-1.1	A9I	Neutral	0.001
NPHS1	O60500-1.1	A9K	Neutral	0.001
NPHS1	O60500-1.1	A9L	Neutral	0.001
NPHS1	O60500-1.1	A9M	Neutral	0.001
NPHS1	O60500-1.1	A9N	Neutral	0.0
NPHS1	O60500-1.1	A9P	Neutral	0.0
NPHS1	O60500-1.1	A9Q	Neutral	0.0
NPHS1	O60500-1.1	A9R	Neutral	0.002
NPHS1	O60500-1.1	A9S	Neutral	0.0
NPHS1	O60500-1.1	A9T	Neutral	0.0
NPHS1	O60500-1.1	A9V	Neutral	0.001
NPHS1	O60500-1.1	A9W	Neutral	0.003
NPHS1	O60500-1.1	A9Y	Neutral	0.0
NPHS1	O60500-1.1	S10A	Neutral	0.0
NPHS1	O60500-1.1	S10C	Neutral	0.0
NPHS1	O60500-1.1	S10D	Neutral	0.0
NPHS1	O60500-1.1	S10E	Neutral	0.0
NPHS1	O60500-1.1	S10F	Neutral	0.0
NPHS1	O60500-1.1	S10G	Neutral	0.0
NPHS1	O60500-1.1	S10H	Neutral	0.0
NPHS1	O60500-1.1	S10I	Neutral	0.0
NPHS1	O60500-1.1	S10K	Neutral	0.0
NPHS1	O60500-1.1	S10L	Neutral	0.0
NPHS1	O60500-1.1	S10M	Neutral	0.0
NPHS1	O60500-1.1	S10N	Neutral	0.0
NPHS1	O60500-1.1	S10P	Neutral	0.0
NPHS1	O60500-1.1	S10Q	Neutral	0.0
NPHS1	O60500-1.1	S10R	Neutral	0.0
NPHS1	O60500-1.1	S10T	Neutral	0.0
NPHS1	O60500-1.1	S10V	Neutral	0.0
NPHS1	O60500-1.1	S10W	Neutral	0.0
NPHS1	O60500-1.1	S10Y	Neutral	0.0
NPHS1	O60500-1.1	L11A	Neutral	0.018
NPHS1	O60500-1.1	L11C	Neutral	0.004
NPHS1	O60500-1.1	L11D	Neutral	0.016
NPHS1	O60500-1.1	L11E	Neutral	0.013
NPHS1	O60500-1.1	L11F	Neutral	0.001
NPHS1	O60500-1.1	L11G	Neutral	0.014
NPHS1	O60500-1.1	L11H	Neutral	0.003
NPHS1	O60500-1.1	L11I	Neutral	0.002
NPHS1	O60500-1.1	L11K	Neutral	0.028
NPHS1	O60500-1.1	L11M	Neutral	0.004
NPHS1	O60500-1.1	L11N	Neutral	0.016
NPHS1	O60500-1.1	L11P	Neutral	0.003
NPHS1	O60500-1.1	L11Q	Neutral	0.009
NPHS1	O60500-1.1	L11R	Neutral	0.039
NPHS1	O60500-1.1	L11S	Neutral	0.018
NPHS1	O60500-1.1	L11T	Neutral	0.011
NPHS1	O60500-1.1	L11V	Neutral	0.004
NPHS1	O60500-1.1	L11W	Neutral	0.002
NPHS1	O60500-1.1	L11Y	Neutral	0.003
NPHS1	O60500-1.1	L12A	Neutral	0.016
NPHS1	O60500-1.1	L12C	Neutral	0.004
NPHS1	O60500-1.1	L12D	Neutral	0.013
NPHS1	O60500-1.1	L12E	Neutral	0.011
NPHS1	O60500-1.1	L12F	Neutral	0.001
NPHS1	O60500-1.1	L12G	Neutral	0.012
NPHS1	O60500-1.1	L12H	Neutral	0.003
NPHS1	O60500-1.1	L12I	Neutral	0.002
NPHS1	O60500-1.1	L12K	Neutral	0.024
NPHS1	O60500-1.1	L12M	Neutral	0.003
NPHS1	O60500-1.1	L12N	Neutral	0.014
NPHS1	O60500-1.1	L12P	Neutral	0.002
NPHS1	O60500-1.1	L12Q	Neutral	0.008
NPHS1	O60500-1.1	L12R	Neutral	0.033
NPHS1	O60500-1.1	L12S	Neutral	0.015
NPHS1	O60500-1.1	L12T	Neutral	0.009
NPHS1	O60500-1.1	L12V	Neutral	0.004
NPHS1	O60500-1.1	L12W	Neutral	0.002
NPHS1	O60500-1.1	L12Y	Neutral	0.002
NPHS1	O60500-1.1	L13A	Neutral	0.03
NPHS1	O60500-1.1	L13C	Neutral	0.007
NPHS1	O60500-1.1	L13D	Neutral	0.026
NPHS1	O60500-1.1	L13E	Neutral	0.021
NPHS1	O60500-1.1	L13F	Neutral	0.002
NPHS1	O60500-1.1	L13G	Neutral	0.023
NPHS1	O60500-1.1	L13H	Neutral	0.005
NPHS1	O60500-1.1	L13I	Neutral	0.004
NPHS1	O60500-1.1	L13K	Neutral	0.047
NPHS1	O60500-1.1	L13M	Neutral	0.007
NPHS1	O60500-1.1	L13N	Neutral	0.027
NPHS1	O60500-1.1	L13P	Neutral	0.004
NPHS1	O60500-1.1	L13Q	Neutral	0.015
NPHS1	O60500-1.1	L13R	Neutral	0.064
NPHS1	O60500-1.1	L13S	Neutral	0.03
NPHS1	O60500-1.1	L13T	Neutral	0.018
NPHS1	O60500-1.1	L13V	Neutral	0.007
NPHS1	O60500-1.1	L13W	Neutral	0.004
NPHS1	O60500-1.1	L13Y	Neutral	0.005
NPHS1	O60500-1.1	L14A	Neutral	0.001
NPHS1	O60500-1.1	L14C	Neutral	0.0
NPHS1	O60500-1.1	L14D	Neutral	0.001
NPHS1	O60500-1.1	L14E	Neutral	0.001
NPHS1	O60500-1.1	L14F	Neutral	0.0
NPHS1	O60500-1.1	L14G	Neutral	0.001
NPHS1	O60500-1.1	L14H	Neutral	0.0
NPHS1	O60500-1.1	L14I	Neutral	0.0
NPHS1	O60500-1.1	L14K	Neutral	0.001
NPHS1	O60500-1.1	L14M	Neutral	0.0
NPHS1	O60500-1.1	L14N	Neutral	0.001
NPHS1	O60500-1.1	L14P	Neutral	0.0
NPHS1	O60500-1.1	L14Q	Neutral	0.0
NPHS1	O60500-1.1	L14R	Neutral	0.002
NPHS1	O60500-1.1	L14S	Neutral	0.001
NPHS1	O60500-1.1	L14T	Neutral	0.0
NPHS1	O60500-1.1	L14V	Neutral	0.0
NPHS1	O60500-1.1	L14W	Neutral	0.0
NPHS1	O60500-1.1	L14Y	Neutral	0.0
NPHS1	O60500-1.1	G15A	Neutral	0.01
NPHS1	O60500-1.1	G15C	Neutral	0.013
NPHS1	O60500-1.1	G15D	Neutral	0.023
NPHS1	O60500-1.1	G15E	Neutral	0.019
NPHS1	O60500-1.1	G15F	Neutral	0.119
NPHS1	O60500-1.1	G15H	Neutral	0.011
NPHS1	O60500-1.1	G15I	Neutral	0.067
NPHS1	O60500-1.1	G15K	Neutral	0.058
NPHS1	O60500-1.1	G15L	Neutral	0.058
NPHS1	O60500-1.1	G15M	Neutral	0.043
NPHS1	O60500-1.1	G15N	Neutral	0.03
NPHS1	O60500-1.1	G15P	Neutral	0.014
NPHS1	O60500-1.1	G15Q	Neutral	0.012
NPHS1	O60500-1.1	G15R	Neutral	0.078
NPHS1	O60500-1.1	G15S	Neutral	0.008
NPHS1	O60500-1.1	G15T	Neutral	0.008
NPHS1	O60500-1.1	G15V	Neutral	0.028
NPHS1	O60500-1.1	G15W	Neutral	0.437
NPHS1	O60500-1.1	G15Y	Neutral	0.043
NPHS1	O60500-1.1	L16A	Neutral	0.007
NPHS1	O60500-1.1	L16C	Neutral	0.002
NPHS1	O60500-1.1	L16D	Neutral	0.006
NPHS1	O60500-1.1	L16E	Neutral	0.005
NPHS1	O60500-1.1	L16F	Neutral	0.001
NPHS1	O60500-1.1	L16G	Neutral	0.005
NPHS1	O60500-1.1	L16H	Neutral	0.001
NPHS1	O60500-1.1	L16I	Neutral	0.001
NPHS1	O60500-1.1	L16K	Neutral	0.011
NPHS1	O60500-1.1	L16M	Neutral	0.002
NPHS1	O60500-1.1	L16N	Neutral	0.006
NPHS1	O60500-1.1	L16P	Neutral	0.001
NPHS1	O60500-1.1	L16Q	Neutral	0.003
NPHS1	O60500-1.1	L16R	Neutral	0.015
NPHS1	O60500-1.1	L16S	Neutral	0.007
NPHS1	O60500-1.1	L16T	Neutral	0.004
NPHS1	O60500-1.1	L16V	Neutral	0.002
NPHS1	O60500-1.1	L16W	Neutral	0.001
NPHS1	O60500-1.1	L16Y	Neutral	0.001
NPHS1	O60500-1.1	L17A	Neutral	0.344
NPHS1	O60500-1.1	L17C	Neutral	0.109
NPHS1	O60500-1.1	L17D	Neutral	0.308
NPHS1	O60500-1.1	L17E	Neutral	0.263
NPHS1	O60500-1.1	L17F	Neutral	0.036
NPHS1	O60500-1.1	L17G	Neutral	0.281
NPHS1	O60500-1.1	L17H	Neutral	0.084
NPHS1	O60500-1.1	L17I	Neutral	0.062
NPHS1	O60500-1.1	L17K	Neutral	0.449
NPHS1	O60500-1.1	L17M	Neutral	0.102
NPHS1	O60500-1.1	L17N	Neutral	0.314
NPHS1	O60500-1.1	L17P	Neutral	0.069
NPHS1	O60500-1.1	L17Q	Neutral	0.202
NPHS1	O60500-1.1	L17R	Pathogenic	0.531
NPHS1	O60500-1.1	L17S	Neutral	0.337
NPHS1	O60500-1.1	L17T	Neutral	0.234
NPHS1	O60500-1.1	L17V	Neutral	0.109
NPHS1	O60500-1.1	L17W	Neutral	0.061
NPHS1	O60500-1.1	L17Y	Neutral	0.071
NPHS1	O60500-1.1	T18A	Neutral	0.0
NPHS1	O60500-1.1	T18C	Neutral	0.001
NPHS1	O60500-1.1	T18D	Neutral	0.001
NPHS1	O60500-1.1	T18E	Neutral	0.001
NPHS1	O60500-1.1	T18F	Neutral	0.003
NPHS1	O60500-1.1	T18G	Neutral	0.0
NPHS1	O60500-1.1	T18H	Neutral	0.0
NPHS1	O60500-1.1	T18I	Neutral	0.003
NPHS1	O60500-1.1	T18K	Neutral	0.003
NPHS1	O60500-1.1	T18L	Neutral	0.003
NPHS1	O60500-1.1	T18M	Neutral	0.001
NPHS1	O60500-1.1	T18N	Neutral	0.001
NPHS1	O60500-1.1	T18P	Neutral	0.0
NPHS1	O60500-1.1	T18Q	Neutral	0.001
NPHS1	O60500-1.1	T18R	Neutral	0.004
NPHS1	O60500-1.1	T18S	Neutral	0.001
NPHS1	O60500-1.1	T18V	Neutral	0.001
NPHS1	O60500-1.1	T18W	Neutral	0.011
NPHS1	O60500-1.1	T18Y	Neutral	0.001
NPHS1	O60500-1.1	E19A	Neutral	0.0
NPHS1	O60500-1.1	E19C	Neutral	0.0
NPHS1	O60500-1.1	E19D	Neutral	0.0
NPHS1	O60500-1.1	E19F	Neutral	0.0
NPHS1	O60500-1.1	E19G	Neutral	0.0
NPHS1	O60500-1.1	E19H	Neutral	0.0
NPHS1	O60500-1.1	E19I	Neutral	0.0
NPHS1	O60500-1.1	E19K	Neutral	0.0
NPHS1	O60500-1.1	E19L	Neutral	0.0
NPHS1	O60500-1.1	E19M	Neutral	0.0
NPHS1	O60500-1.1	E19N	Neutral	0.0
NPHS1	O60500-1.1	E19P	Neutral	0.0
NPHS1	O60500-1.1	E19Q	Neutral	0.0
NPHS1	O60500-1.1	E19R	Neutral	0.0
NPHS1	O60500-1.1	E19S	Neutral	0.0
NPHS1	O60500-1.1	E19T	Neutral	0.0
NPHS1	O60500-1.1	E19V	Neutral	0.0
NPHS1	O60500-1.1	E19W	Neutral	0.002
NPHS1	O60500-1.1	E19Y	Neutral	0.0
NPHS1	O60500-1.1	G20A	Neutral	0.05
NPHS1	O60500-1.1	G20C	Neutral	0.064
NPHS1	O60500-1.1	G20D	Neutral	0.11
NPHS1	O60500-1.1	G20E	Neutral	0.095
NPHS1	O60500-1.1	G20F	Neutral	0.418
NPHS1	O60500-1.1	G20H	Neutral	0.057
NPHS1	O60500-1.1	G20I	Neutral	0.275
NPHS1	O60500-1.1	G20K	Neutral	0.246
NPHS1	O60500-1.1	G20L	Neutral	0.246
NPHS1	O60500-1.1	G20M	Neutral	0.195
NPHS1	O60500-1.1	G20N	Neutral	0.139
NPHS1	O60500-1.1	G20P	Neutral	0.07
NPHS1	O60500-1.1	G20Q	Neutral	0.059
NPHS1	O60500-1.1	G20R	Neutral	0.312
NPHS1	O60500-1.1	G20S	Neutral	0.039
NPHS1	O60500-1.1	G20T	Neutral	0.039
NPHS1	O60500-1.1	G20V	Neutral	0.131
NPHS1	O60500-1.1	G20W	Pathogenic	0.805
NPHS1	O60500-1.1	G20Y	Neutral	0.195
NPHS1	O60500-1.1	L21A	Neutral	0.053
NPHS1	O60500-1.1	L21C	Neutral	0.013
NPHS1	O60500-1.1	L21D	Neutral	0.045
NPHS1	O60500-1.1	L21E	Neutral	0.037
NPHS1	O60500-1.1	L21F	Neutral	0.004
NPHS1	O60500-1.1	L21G	Neutral	0.04
NPHS1	O60500-1.1	L21H	Neutral	0.01
NPHS1	O60500-1.1	L21I	Neutral	0.007
NPHS1	O60500-1.1	L21K	Neutral	0.08
NPHS1	O60500-1.1	L21M	Neutral	0.012
NPHS1	O60500-1.1	L21N	Neutral	0.047
NPHS1	O60500-1.1	L21P	Neutral	0.008
NPHS1	O60500-1.1	L21Q	Neutral	0.026
NPHS1	O60500-1.1	L21R	Neutral	0.108
NPHS1	O60500-1.1	L21S	Neutral	0.052
NPHS1	O60500-1.1	L21T	Neutral	0.032
NPHS1	O60500-1.1	L21V	Neutral	0.013
NPHS1	O60500-1.1	L21W	Neutral	0.007
NPHS1	O60500-1.1	L21Y	Neutral	0.008
NPHS1	O60500-1.1	A22C	Neutral	0.001
NPHS1	O60500-1.1	A22D	Neutral	0.001
NPHS1	O60500-1.1	A22E	Neutral	0.001
NPHS1	O60500-1.1	A22F	Neutral	0.003
NPHS1	O60500-1.1	A22G	Neutral	0.0
NPHS1	O60500-1.1	A22H	Neutral	0.0
NPHS1	O60500-1.1	A22I	Neutral	0.004
NPHS1	O60500-1.1	A22K	Neutral	0.004
NPHS1	O60500-1.1	A22L	Neutral	0.003
NPHS1	O60500-1.1	A22M	Neutral	0.002
NPHS1	O60500-1.1	A22N	Neutral	0.001
NPHS1	O60500-1.1	A22P	Neutral	0.0
NPHS1	O60500-1.1	A22Q	Neutral	0.001
NPHS1	O60500-1.1	A22R	Neutral	0.005
NPHS1	O60500-1.1	A22S	Neutral	0.0
NPHS1	O60500-1.1	A22T	Neutral	0.0
NPHS1	O60500-1.1	A22V	Neutral	0.001
NPHS1	O60500-1.1	A22W	Neutral	0.008
NPHS1	O60500-1.1	A22Y	Neutral	0.001
NPHS1	O60500-1.1	Q23A	Neutral	0.158
NPHS1	O60500-1.1	Q23C	Neutral	0.128
NPHS1	O60500-1.1	Q23D	Neutral	0.141
NPHS1	O60500-1.1	Q23E	Neutral	0.164
NPHS1	O60500-1.1	Q23F	Neutral	0.293
NPHS1	O60500-1.1	Q23G	Neutral	0.111
NPHS1	O60500-1.1	Q23H	Neutral	0.072
NPHS1	O60500-1.1	Q23I	Neutral	0.246
NPHS1	O60500-1.1	Q23K	Neutral	0.245
NPHS1	O60500-1.1	Q23L	Neutral	0.294
NPHS1	O60500-1.1	Q23M	Neutral	0.316
NPHS1	O60500-1.1	Q23N	Neutral	0.102
NPHS1	O60500-1.1	Q23P	Neutral	0.167
NPHS1	O60500-1.1	Q23R	Neutral	0.31
NPHS1	O60500-1.1	Q23S	Neutral	0.127
NPHS1	O60500-1.1	Q23T	Neutral	0.086
NPHS1	O60500-1.1	Q23V	Neutral	0.166
NPHS1	O60500-1.1	Q23W	Pathogenic	0.704
NPHS1	O60500-1.1	Q23Y	Neutral	0.236
NPHS1	O60500-1.1	L24A	Neutral	0.025
NPHS1	O60500-1.1	L24C	Neutral	0.006
NPHS1	O60500-1.1	L24D	Neutral	0.021
NPHS1	O60500-1.1	L24E	Neutral	0.017
NPHS1	O60500-1.1	L24F	Neutral	0.002
NPHS1	O60500-1.1	L24G	Neutral	0.019
NPHS1	O60500-1.1	L24H	Neutral	0.004
NPHS1	O60500-1.1	L24I	Neutral	0.003
NPHS1	O60500-1.1	L24K	Neutral	0.038
NPHS1	O60500-1.1	L24M	Neutral	0.006
NPHS1	O60500-1.1	L24N	Neutral	0.022
NPHS1	O60500-1.1	L24P	Neutral	0.004
NPHS1	O60500-1.1	L24Q	Neutral	0.012
NPHS1	O60500-1.1	L24R	Neutral	0.052
NPHS1	O60500-1.1	L24S	Neutral	0.024
NPHS1	O60500-1.1	L24T	Neutral	0.015
NPHS1	O60500-1.1	L24V	Neutral	0.006
NPHS1	O60500-1.1	L24W	Neutral	0.003
NPHS1	O60500-1.1	L24Y	Neutral	0.004
NPHS1	O60500-1.1	A25C	Neutral	0.001
NPHS1	O60500-1.1	A25D	Neutral	0.001
NPHS1	O60500-1.1	A25E	Neutral	0.001
NPHS1	O60500-1.1	A25F	Neutral	0.004
NPHS1	O60500-1.1	A25G	Neutral	0.0
NPHS1	O60500-1.1	A25H	Neutral	0.0
NPHS1	O60500-1.1	A25I	Neutral	0.004
NPHS1	O60500-1.1	A25K	Neutral	0.004
NPHS1	O60500-1.1	A25L	Neutral	0.004
NPHS1	O60500-1.1	A25M	Neutral	0.002
NPHS1	O60500-1.1	A25N	Neutral	0.001
NPHS1	O60500-1.1	A25P	Neutral	0.0
NPHS1	O60500-1.1	A25Q	Neutral	0.001
NPHS1	O60500-1.1	A25R	Neutral	0.006
NPHS1	O60500-1.1	A25S	Neutral	0.001
NPHS1	O60500-1.1	A25T	Neutral	0.0
NPHS1	O60500-1.1	A25V	Neutral	0.002
NPHS1	O60500-1.1	A25W	Neutral	0.01
NPHS1	O60500-1.1	A25Y	Neutral	0.001
NPHS1	O60500-1.1	I26A	Pathogenic	0.51
NPHS1	O60500-1.1	I26C	Neutral	0.196
NPHS1	O60500-1.1	I26D	Pathogenic	0.569
NPHS1	O60500-1.1	I26E	Neutral	0.415
NPHS1	O60500-1.1	I26F	Neutral	0.055
NPHS1	O60500-1.1	I26G	Neutral	0.437
NPHS1	O60500-1.1	I26H	Neutral	0.154
NPHS1	O60500-1.1	I26K	Pathogenic	0.521
NPHS1	O60500-1.1	I26L	Neutral	0.102
NPHS1	O60500-1.1	I26M	Neutral	0.132
NPHS1	O60500-1.1	I26N	Neutral	0.477
NPHS1	O60500-1.1	I26P	Neutral	0.129
NPHS1	O60500-1.1	I26Q	Neutral	0.253
NPHS1	O60500-1.1	I26R	Pathogenic	0.602
NPHS1	O60500-1.1	I26S	Pathogenic	0.503
NPHS1	O60500-1.1	I26T	Neutral	0.378
NPHS1	O60500-1.1	I26V	Neutral	0.352
NPHS1	O60500-1.1	I26W	Neutral	0.06
NPHS1	O60500-1.1	I26Y	Neutral	0.133
NPHS1	O60500-1.1	P27A	Neutral	0.083
NPHS1	O60500-1.1	P27C	Neutral	0.02
NPHS1	O60500-1.1	P27D	Neutral	0.211
NPHS1	O60500-1.1	P27E	Neutral	0.251
NPHS1	O60500-1.1	P27F	Neutral	0.109
NPHS1	O60500-1.1	P27G	Neutral	0.13
NPHS1	O60500-1.1	P27H	Neutral	0.081
NPHS1	O60500-1.1	P27I	Neutral	0.126
NPHS1	O60500-1.1	P27K	Pathogenic	0.511
NPHS1	O60500-1.1	P27L	Neutral	0.11
NPHS1	O60500-1.1	P27M	Neutral	0.084
NPHS1	O60500-1.1	P27N	Neutral	0.135
NPHS1	O60500-1.1	P27Q	Neutral	0.169
NPHS1	O60500-1.1	P27R	Neutral	0.494
NPHS1	O60500-1.1	P27S	Neutral	0.116
NPHS1	O60500-1.1	P27T	Neutral	0.057
NPHS1	O60500-1.1	P27V	Neutral	0.054
NPHS1	O60500-1.1	P27W	Neutral	0.32
NPHS1	O60500-1.1	P27Y	Neutral	0.058
NPHS1	O60500-1.1	A28C	Neutral	0.067
NPHS1	O60500-1.1	A28D	Neutral	0.062
NPHS1	O60500-1.1	A28E	Neutral	0.111
NPHS1	O60500-1.1	A28F	Neutral	0.255
NPHS1	O60500-1.1	A28G	Neutral	0.04
NPHS1	O60500-1.1	A28H	Neutral	0.032
NPHS1	O60500-1.1	A28I	Neutral	0.287
NPHS1	O60500-1.1	A28K	Neutral	0.28
NPHS1	O60500-1.1	A28L	Neutral	0.257
NPHS1	O60500-1.1	A28M	Neutral	0.147
NPHS1	O60500-1.1	A28N	Neutral	0.055
NPHS1	O60500-1.1	A28P	Neutral	0.035
NPHS1	O60500-1.1	A28Q	Neutral	0.07
NPHS1	O60500-1.1	A28R	Neutral	0.351
NPHS1	O60500-1.1	A28S	Neutral	0.046
NPHS1	O60500-1.1	A28T	Neutral	0.033
NPHS1	O60500-1.1	A28V	Neutral	0.138
NPHS1	O60500-1.1	A28W	Neutral	0.469
NPHS1	O60500-1.1	A28Y	Neutral	0.103
NPHS1	O60500-1.1	S29A	Neutral	0.048
NPHS1	O60500-1.1	S29C	Neutral	0.069
NPHS1	O60500-1.1	S29D	Neutral	0.075
NPHS1	O60500-1.1	S29E	Neutral	0.092
NPHS1	O60500-1.1	S29F	Neutral	0.343
NPHS1	O60500-1.1	S29G	Neutral	0.033
NPHS1	O60500-1.1	S29H	Neutral	0.042
NPHS1	O60500-1.1	S29I	Neutral	0.291
NPHS1	O60500-1.1	S29K	Neutral	0.241
NPHS1	O60500-1.1	S29L	Neutral	0.261
NPHS1	O60500-1.1	S29M	Neutral	0.207
NPHS1	O60500-1.1	S29N	Neutral	0.095
NPHS1	O60500-1.1	S29P	Neutral	0.052
NPHS1	O60500-1.1	S29Q	Neutral	0.058
NPHS1	O60500-1.1	S29R	Neutral	0.228
NPHS1	O60500-1.1	S29T	Neutral	0.062
NPHS1	O60500-1.1	S29V	Neutral	0.099
NPHS1	O60500-1.1	S29W	Pathogenic	0.574
NPHS1	O60500-1.1	S29Y	Neutral	0.149
NPHS1	O60500-1.1	V30A	Neutral	0.032
NPHS1	O60500-1.1	V30C	Neutral	0.005
NPHS1	O60500-1.1	V30D	Neutral	0.027
NPHS1	O60500-1.1	V30E	Neutral	0.026
NPHS1	O60500-1.1	V30F	Neutral	0.011
NPHS1	O60500-1.1	V30G	Neutral	0.024
NPHS1	O60500-1.1	V30H	Neutral	0.007
NPHS1	O60500-1.1	V30I	Neutral	0.042
NPHS1	O60500-1.1	V30K	Neutral	0.078
NPHS1	O60500-1.1	V30L	Neutral	0.016
NPHS1	O60500-1.1	V30M	Neutral	0.008
NPHS1	O60500-1.1	V30N	Neutral	0.019
NPHS1	O60500-1.1	V30P	Neutral	0.005
NPHS1	O60500-1.1	V30Q	Neutral	0.016
NPHS1	O60500-1.1	V30R	Neutral	0.073
NPHS1	O60500-1.1	V30S	Neutral	0.021
NPHS1	O60500-1.1	V30T	Neutral	0.019
NPHS1	O60500-1.1	V30W	Neutral	0.019
NPHS1	O60500-1.1	V30Y	Neutral	0.008
NPHS1	O60500-1.1	P31A	Neutral	0.191
NPHS1	O60500-1.1	P31C	Neutral	0.052
NPHS1	O60500-1.1	P31D	Neutral	0.411
NPHS1	O60500-1.1	P31E	Neutral	0.467
NPHS1	O60500-1.1	P31F	Neutral	0.242
NPHS1	O60500-1.1	P31G	Neutral	0.281
NPHS1	O60500-1.1	P31H	Neutral	0.188
NPHS1	O60500-1.1	P31I	Neutral	0.273
NPHS1	O60500-1.1	P31K	Pathogenic	0.732
NPHS1	O60500-1.1	P31L	Neutral	0.243
NPHS1	O60500-1.1	P31M	Neutral	0.193
NPHS1	O60500-1.1	P31N	Neutral	0.29
NPHS1	O60500-1.1	P31Q	Neutral	0.346
NPHS1	O60500-1.1	P31R	Pathogenic	0.718
NPHS1	O60500-1.1	P31S	Neutral	0.255
NPHS1	O60500-1.1	P31T	Neutral	0.137
NPHS1	O60500-1.1	P31V	Neutral	0.13
NPHS1	O60500-1.1	P31W	Pathogenic	0.551
NPHS1	O60500-1.1	P31Y	Neutral	0.138
NPHS1	O60500-1.1	R32A	Pathogenic	0.968
NPHS1	O60500-1.1	R32C	Pathogenic	0.959
NPHS1	O60500-1.1	R32D	Pathogenic	0.696
NPHS1	O60500-1.1	R32E	Pathogenic	0.802
NPHS1	O60500-1.1	R32F	Pathogenic	0.961
NPHS1	O60500-1.1	R32G	Pathogenic	0.952
NPHS1	O60500-1.1	R32H	Pathogenic	0.912
NPHS1	O60500-1.1	R32I	Pathogenic	0.97
NPHS1	O60500-1.1	R32K	Pathogenic	0.743
NPHS1	O60500-1.1	R32L	Pathogenic	0.977
NPHS1	O60500-1.1	R32M	Pathogenic	0.969
NPHS1	O60500-1.1	R32N	Pathogenic	0.854
NPHS1	O60500-1.1	R32P	Pathogenic	0.956
NPHS1	O60500-1.1	R32Q	Pathogenic	0.909
NPHS1	O60500-1.1	R32S	Pathogenic	0.94
NPHS1	O60500-1.1	R32T	Pathogenic	0.938
NPHS1	O60500-1.1	R32V	Pathogenic	0.955
NPHS1	O60500-1.1	R32W	Pathogenic	0.981
NPHS1	O60500-1.1	R32Y	Pathogenic	0.902
NPHS1	O60500-1.1	G33A	Neutral	0.105
NPHS1	O60500-1.1	G33C	Neutral	0.131
NPHS1	O60500-1.1	G33D	Neutral	0.216
NPHS1	O60500-1.1	G33E	Neutral	0.188
NPHS1	O60500-1.1	G33F	Pathogenic	0.615
NPHS1	O60500-1.1	G33H	Neutral	0.119
NPHS1	O60500-1.1	G33I	Neutral	0.457
NPHS1	O60500-1.1	G33K	Neutral	0.42
NPHS1	O60500-1.1	G33L	Neutral	0.42
NPHS1	O60500-1.1	G33M	Neutral	0.349
NPHS1	O60500-1.1	G33N	Neutral	0.265
NPHS1	O60500-1.1	G33P	Neutral	0.143
NPHS1	O60500-1.1	G33Q	Neutral	0.123
NPHS1	O60500-1.1	G33R	Pathogenic	0.502
NPHS1	O60500-1.1	G33S	Neutral	0.083
NPHS1	O60500-1.1	G33T	Neutral	0.083
NPHS1	O60500-1.1	G33V	Neutral	0.251
NPHS1	O60500-1.1	G33W	Pathogenic	0.902
NPHS1	O60500-1.1	G33Y	Neutral	0.349
NPHS1	O60500-1.1	F34A	Pathogenic	0.999
NPHS1	O60500-1.1	F34C	Pathogenic	0.994
NPHS1	O60500-1.1	F34D	Pathogenic	0.999
NPHS1	O60500-1.1	F34E	Pathogenic	0.999
NPHS1	O60500-1.1	F34G	Pathogenic	0.999
NPHS1	O60500-1.1	F34H	Pathogenic	0.998
NPHS1	O60500-1.1	F34I	Pathogenic	0.981
NPHS1	O60500-1.1	F34K	Pathogenic	0.999
NPHS1	O60500-1.1	F34L	Pathogenic	0.983
NPHS1	O60500-1.1	F34M	Pathogenic	0.991
NPHS1	O60500-1.1	F34N	Pathogenic	0.999
NPHS1	O60500-1.1	F34P	Pathogenic	0.991
NPHS1	O60500-1.1	F34Q	Pathogenic	0.997
NPHS1	O60500-1.1	F34R	Pathogenic	0.999
NPHS1	O60500-1.1	F34S	Pathogenic	0.999
NPHS1	O60500-1.1	F34T	Pathogenic	0.998
NPHS1	O60500-1.1	F34V	Pathogenic	0.992
NPHS1	O60500-1.1	F34W	Pathogenic	0.995
NPHS1	O60500-1.1	F34Y	Pathogenic	0.998
NPHS1	O60500-1.1	W35A	Pathogenic	0.99
NPHS1	O60500-1.1	W35C	Pathogenic	0.971
NPHS1	O60500-1.1	W35D	Pathogenic	0.995
NPHS1	O60500-1.1	W35E	Pathogenic	0.993
NPHS1	O60500-1.1	W35F	Pathogenic	0.914
NPHS1	O60500-1.1	W35G	Pathogenic	0.997
NPHS1	O60500-1.1	W35H	Pathogenic	0.983
NPHS1	O60500-1.1	W35I	Pathogenic	0.731
NPHS1	O60500-1.1	W35K	Pathogenic	0.993
NPHS1	O60500-1.1	W35L	Pathogenic	0.825
NPHS1	O60500-1.1	W35M	Pathogenic	0.934
NPHS1	O60500-1.1	W35N	Pathogenic	0.992
NPHS1	O60500-1.1	W35P	Pathogenic	0.953
NPHS1	O60500-1.1	W35Q	Pathogenic	0.991
NPHS1	O60500-1.1	W35R	Pathogenic	0.99
NPHS1	O60500-1.1	W35S	Pathogenic	0.993
NPHS1	O60500-1.1	W35T	Pathogenic	0.988
NPHS1	O60500-1.1	W35V	Pathogenic	0.911
NPHS1	O60500-1.1	W35Y	Pathogenic	0.979
NPHS1	O60500-1.1	A36C	Neutral	0.195
NPHS1	O60500-1.1	A36D	Neutral	0.182
NPHS1	O60500-1.1	A36E	Neutral	0.295
NPHS1	O60500-1.1	A36F	Pathogenic	0.535
NPHS1	O60500-1.1	A36G	Neutral	0.123
NPHS1	O60500-1.1	A36H	Neutral	0.099
NPHS1	O60500-1.1	A36I	Pathogenic	0.575
NPHS1	O60500-1.1	A36K	Pathogenic	0.566
NPHS1	O60500-1.1	A36L	Pathogenic	0.537
NPHS1	O60500-1.1	A36M	Neutral	0.366
NPHS1	O60500-1.1	A36N	Neutral	0.163
NPHS1	O60500-1.1	A36P	Neutral	0.107
NPHS1	O60500-1.1	A36Q	Neutral	0.202
NPHS1	O60500-1.1	A36R	Pathogenic	0.645
NPHS1	O60500-1.1	A36S	Neutral	0.14
NPHS1	O60500-1.1	A36T	Neutral	0.101
NPHS1	O60500-1.1	A36V	Neutral	0.35
NPHS1	O60500-1.1	A36W	Pathogenic	0.748
NPHS1	O60500-1.1	A36Y	Neutral	0.279
NPHS1	O60500-1.1	L37A	Pathogenic	0.583
NPHS1	O60500-1.1	L37C	Neutral	0.247
NPHS1	O60500-1.1	L37D	Pathogenic	0.544
NPHS1	O60500-1.1	L37E	Neutral	0.488
NPHS1	O60500-1.1	L37F	Neutral	0.092
NPHS1	O60500-1.1	L37G	Pathogenic	0.511
NPHS1	O60500-1.1	L37H	Neutral	0.197
NPHS1	O60500-1.1	L37I	Neutral	0.15
NPHS1	O60500-1.1	L37K	Pathogenic	0.686
NPHS1	O60500-1.1	L37M	Neutral	0.234
NPHS1	O60500-1.1	L37N	Pathogenic	0.551
NPHS1	O60500-1.1	L37P	Neutral	0.166
NPHS1	O60500-1.1	L37Q	Neutral	0.404
NPHS1	O60500-1.1	L37R	Pathogenic	0.752
NPHS1	O60500-1.1	L37S	Pathogenic	0.576
NPHS1	O60500-1.1	L37T	Neutral	0.45
NPHS1	O60500-1.1	L37V	Neutral	0.247
NPHS1	O60500-1.1	L37W	Neutral	0.149
NPHS1	O60500-1.1	L37Y	Neutral	0.171
NPHS1	O60500-1.1	P38A	Pathogenic	0.857
NPHS1	O60500-1.1	P38C	Pathogenic	0.581
NPHS1	O60500-1.1	P38D	Pathogenic	0.947
NPHS1	O60500-1.1	P38E	Pathogenic	0.957
NPHS1	O60500-1.1	P38F	Pathogenic	0.89
NPHS1	O60500-1.1	P38G	Pathogenic	0.909
NPHS1	O60500-1.1	P38H	Pathogenic	0.855
NPHS1	O60500-1.1	P38I	Pathogenic	0.905
NPHS1	O60500-1.1	P38K	Pathogenic	0.986
NPHS1	O60500-1.1	P38L	Pathogenic	0.891
NPHS1	O60500-1.1	P38M	Pathogenic	0.859
NPHS1	O60500-1.1	P38N	Pathogenic	0.912
NPHS1	O60500-1.1	P38Q	Pathogenic	0.931
NPHS1	O60500-1.1	P38R	Pathogenic	0.985
NPHS1	O60500-1.1	P38S	Pathogenic	0.897
NPHS1	O60500-1.1	P38T	Pathogenic	0.802
NPHS1	O60500-1.1	P38V	Pathogenic	0.792
NPHS1	O60500-1.1	P38W	Pathogenic	0.969
NPHS1	O60500-1.1	P38Y	Pathogenic	0.803
NPHS1	O60500-1.1	E39A	Neutral	0.375
NPHS1	O60500-1.1	E39C	Neutral	0.24
NPHS1	O60500-1.1	E39D	Neutral	0.252
NPHS1	O60500-1.1	E39F	Pathogenic	0.626
NPHS1	O60500-1.1	E39G	Neutral	0.285
NPHS1	O60500-1.1	E39H	Neutral	0.24
NPHS1	O60500-1.1	E39I	Pathogenic	0.569
NPHS1	O60500-1.1	E39K	Neutral	0.274
NPHS1	O60500-1.1	E39L	Pathogenic	0.531
NPHS1	O60500-1.1	E39M	Neutral	0.457
NPHS1	O60500-1.1	E39N	Neutral	0.105
NPHS1	O60500-1.1	E39P	Neutral	0.391
NPHS1	O60500-1.1	E39Q	Neutral	0.275
NPHS1	O60500-1.1	E39R	Neutral	0.261
NPHS1	O60500-1.1	E39S	Neutral	0.318
NPHS1	O60500-1.1	E39T	Neutral	0.231
NPHS1	O60500-1.1	E39V	Neutral	0.388
NPHS1	O60500-1.1	E39W	Pathogenic	0.866
NPHS1	O60500-1.1	E39Y	Neutral	0.456
NPHS1	O60500-1.1	N40A	Pathogenic	0.824
NPHS1	O60500-1.1	N40C	Pathogenic	0.845
NPHS1	O60500-1.1	N40D	Pathogenic	0.745
NPHS1	O60500-1.1	N40E	Pathogenic	0.66
NPHS1	O60500-1.1	N40F	Pathogenic	0.973
NPHS1	O60500-1.1	N40G	Pathogenic	0.911
NPHS1	O60500-1.1	N40H	Pathogenic	0.91
NPHS1	O60500-1.1	N40I	Pathogenic	0.966
NPHS1	O60500-1.1	N40K	Pathogenic	0.858
NPHS1	O60500-1.1	N40L	Pathogenic	0.96
NPHS1	O60500-1.1	N40M	Pathogenic	0.947
NPHS1	O60500-1.1	N40P	Pathogenic	0.833
NPHS1	O60500-1.1	N40Q	Pathogenic	0.785
NPHS1	O60500-1.1	N40R	Pathogenic	0.894
NPHS1	O60500-1.1	N40S	Pathogenic	0.889
NPHS1	O60500-1.1	N40T	Pathogenic	0.839
NPHS1	O60500-1.1	N40V	Pathogenic	0.883
NPHS1	O60500-1.1	N40W	Pathogenic	0.989
NPHS1	O60500-1.1	N40Y	Pathogenic	0.947
NPHS1	O60500-1.1	L41A	Neutral	0.269
NPHS1	O60500-1.1	L41C	Neutral	0.079
NPHS1	O60500-1.1	L41D	Neutral	0.238
NPHS1	O60500-1.1	L41E	Neutral	0.2
NPHS1	O60500-1.1	L41F	Neutral	0.026
NPHS1	O60500-1.1	L41G	Neutral	0.216
NPHS1	O60500-1.1	L41H	Neutral	0.061
NPHS1	O60500-1.1	L41I	Neutral	0.044
NPHS1	O60500-1.1	L41K	Neutral	0.365
NPHS1	O60500-1.1	L41M	Neutral	0.074
NPHS1	O60500-1.1	L41N	Neutral	0.244
NPHS1	O60500-1.1	L41P	Neutral	0.05
NPHS1	O60500-1.1	L41Q	Neutral	0.151
NPHS1	O60500-1.1	L41R	Neutral	0.444
NPHS1	O60500-1.1	L41S	Neutral	0.263
NPHS1	O60500-1.1	L41T	Neutral	0.177
NPHS1	O60500-1.1	L41V	Neutral	0.079
NPHS1	O60500-1.1	L41W	Neutral	0.044
NPHS1	O60500-1.1	L41Y	Neutral	0.051
NPHS1	O60500-1.1	T42A	Pathogenic	0.97
NPHS1	O60500-1.1	T42C	Pathogenic	0.975
NPHS1	O60500-1.1	T42D	Pathogenic	0.982
NPHS1	O60500-1.1	T42E	Pathogenic	0.984
NPHS1	O60500-1.1	T42F	Pathogenic	0.995
NPHS1	O60500-1.1	T42G	Pathogenic	0.969
NPHS1	O60500-1.1	T42H	Pathogenic	0.941
NPHS1	O60500-1.1	T42I	Pathogenic	0.996
NPHS1	O60500-1.1	T42K	Pathogenic	0.995
NPHS1	O60500-1.1	T42L	Pathogenic	0.995
NPHS1	O60500-1.1	T42M	Pathogenic	0.99
NPHS1	O60500-1.1	T42N	Pathogenic	0.984
NPHS1	O60500-1.1	T42P	Pathogenic	0.959
NPHS1	O60500-1.1	T42Q	Pathogenic	0.974
NPHS1	O60500-1.1	T42R	Pathogenic	0.996
NPHS1	O60500-1.1	T42S	Pathogenic	0.984
NPHS1	O60500-1.1	T42V	Pathogenic	0.989
NPHS1	O60500-1.1	T42W	Pathogenic	0.999
NPHS1	O60500-1.1	T42Y	Pathogenic	0.985
NPHS1	O60500-1.1	V43A	Pathogenic	0.82
NPHS1	O60500-1.1	V43C	Neutral	0.417
NPHS1	O60500-1.1	V43D	Pathogenic	0.795
NPHS1	O60500-1.1	V43E	Pathogenic	0.789
NPHS1	O60500-1.1	V43F	Pathogenic	0.605
NPHS1	O60500-1.1	V43G	Pathogenic	0.773
NPHS1	O60500-1.1	V43H	Neutral	0.497
NPHS1	O60500-1.1	V43I	Pathogenic	0.856
NPHS1	O60500-1.1	V43K	Pathogenic	0.921
NPHS1	O60500-1.1	V43L	Pathogenic	0.697
NPHS1	O60500-1.1	V43M	Pathogenic	0.534
NPHS1	O60500-1.1	V43N	Pathogenic	0.728
NPHS1	O60500-1.1	V43P	Neutral	0.392
NPHS1	O60500-1.1	V43Q	Pathogenic	0.693
NPHS1	O60500-1.1	V43R	Pathogenic	0.916
NPHS1	O60500-1.1	V43S	Pathogenic	0.748
NPHS1	O60500-1.1	V43T	Pathogenic	0.727
NPHS1	O60500-1.1	V43W	Pathogenic	0.726
NPHS1	O60500-1.1	V43Y	Pathogenic	0.524
NPHS1	O60500-1.1	V44A	Neutral	0.417
NPHS1	O60500-1.1	V44C	Neutral	0.101
NPHS1	O60500-1.1	V44D	Neutral	0.378
NPHS1	O60500-1.1	V44E	Neutral	0.371
NPHS1	O60500-1.1	V44F	Neutral	0.194
NPHS1	O60500-1.1	V44G	Neutral	0.348
NPHS1	O60500-1.1	V44H	Neutral	0.134
NPHS1	O60500-1.1	V44I	Neutral	0.484
NPHS1	O60500-1.1	V44K	Pathogenic	0.648
NPHS1	O60500-1.1	V44L	Neutral	0.266
NPHS1	O60500-1.1	V44M	Neutral	0.153
NPHS1	O60500-1.1	V44N	Neutral	0.296
NPHS1	O60500-1.1	V44P	Neutral	0.092
NPHS1	O60500-1.1	V44Q	Neutral	0.262
NPHS1	O60500-1.1	V44R	Pathogenic	0.631
NPHS1	O60500-1.1	V44S	Neutral	0.318
NPHS1	O60500-1.1	V44T	Neutral	0.295
NPHS1	O60500-1.1	V44W	Neutral	0.294
NPHS1	O60500-1.1	V44Y	Neutral	0.148
NPHS1	O60500-1.1	E45A	Pathogenic	0.76
NPHS1	O60500-1.1	E45C	Pathogenic	0.624
NPHS1	O60500-1.1	E45D	Pathogenic	0.64
NPHS1	O60500-1.1	E45F	Pathogenic	0.898
NPHS1	O60500-1.1	E45G	Pathogenic	0.678
NPHS1	O60500-1.1	E45H	Pathogenic	0.625
NPHS1	O60500-1.1	E45I	Pathogenic	0.874
NPHS1	O60500-1.1	E45K	Pathogenic	0.666
NPHS1	O60500-1.1	E45L	Pathogenic	0.857
NPHS1	O60500-1.1	E45M	Pathogenic	0.816
NPHS1	O60500-1.1	E45N	Neutral	0.381
NPHS1	O60500-1.1	E45P	Pathogenic	0.772
NPHS1	O60500-1.1	E45Q	Pathogenic	0.666
NPHS1	O60500-1.1	E45R	Pathogenic	0.65
NPHS1	O60500-1.1	E45S	Pathogenic	0.71
NPHS1	O60500-1.1	E45T	Pathogenic	0.613
NPHS1	O60500-1.1	E45V	Pathogenic	0.77
NPHS1	O60500-1.1	E45W	Pathogenic	0.971
NPHS1	O60500-1.1	E45Y	Pathogenic	0.816
NPHS1	O60500-1.1	G46A	Pathogenic	0.98
NPHS1	O60500-1.1	G46C	Pathogenic	0.984
NPHS1	O60500-1.1	G46D	Pathogenic	0.991
NPHS1	O60500-1.1	G46E	Pathogenic	0.99
NPHS1	O60500-1.1	G46F	Pathogenic	0.998
NPHS1	O60500-1.1	G46H	Pathogenic	0.982
NPHS1	O60500-1.1	G46I	Pathogenic	0.997
NPHS1	O60500-1.1	G46K	Pathogenic	0.997
NPHS1	O60500-1.1	G46L	Pathogenic	0.997
NPHS1	O60500-1.1	G46M	Pathogenic	0.996
NPHS1	O60500-1.1	G46N	Pathogenic	0.993
NPHS1	O60500-1.1	G46P	Pathogenic	0.986
NPHS1	O60500-1.1	G46Q	Pathogenic	0.983
NPHS1	O60500-1.1	G46R	Pathogenic	0.998
NPHS1	O60500-1.1	G46S	Pathogenic	0.974
NPHS1	O60500-1.1	G46T	Pathogenic	0.974
NPHS1	O60500-1.1	G46V	Pathogenic	0.993
NPHS1	O60500-1.1	G46W	Pathogenic	1.0
NPHS1	O60500-1.1	G46Y	Pathogenic	0.995
NPHS1	O60500-1.1	A47C	Neutral	0.189
NPHS1	O60500-1.1	A47D	Neutral	0.177
NPHS1	O60500-1.1	A47E	Neutral	0.287
NPHS1	O60500-1.1	A47F	Pathogenic	0.526
NPHS1	O60500-1.1	A47G	Neutral	0.119
NPHS1	O60500-1.1	A47H	Neutral	0.096
NPHS1	O60500-1.1	A47I	Pathogenic	0.566
NPHS1	O60500-1.1	A47K	Pathogenic	0.557
NPHS1	O60500-1.1	A47L	Pathogenic	0.528
NPHS1	O60500-1.1	A47M	Neutral	0.357
NPHS1	O60500-1.1	A47N	Neutral	0.158
NPHS1	O60500-1.1	A47P	Neutral	0.104
NPHS1	O60500-1.1	A47Q	Neutral	0.196
NPHS1	O60500-1.1	A47R	Pathogenic	0.636
NPHS1	O60500-1.1	A47S	Neutral	0.135
NPHS1	O60500-1.1	A47T	Neutral	0.098
NPHS1	O60500-1.1	A47V	Neutral	0.341
NPHS1	O60500-1.1	A47W	Pathogenic	0.741
NPHS1	O60500-1.1	A47Y	Neutral	0.271
NPHS1	O60500-1.1	S48A	Neutral	0.001
NPHS1	O60500-1.1	S48C	Neutral	0.001
NPHS1	O60500-1.1	S48D	Neutral	0.001
NPHS1	O60500-1.1	S48E	Neutral	0.002
NPHS1	O60500-1.1	S48F	Neutral	0.009
NPHS1	O60500-1.1	S48G	Neutral	0.001
NPHS1	O60500-1.1	S48H	Neutral	0.001
NPHS1	O60500-1.1	S48I	Neutral	0.007
NPHS1	O60500-1.1	S48K	Neutral	0.005
NPHS1	O60500-1.1	S48L	Neutral	0.006
NPHS1	O60500-1.1	S48M	Neutral	0.004
NPHS1	O60500-1.1	S48N	Neutral	0.002
NPHS1	O60500-1.1	S48P	Neutral	0.001
NPHS1	O60500-1.1	S48Q	Neutral	0.001
NPHS1	O60500-1.1	S48R	Neutral	0.005
NPHS1	O60500-1.1	S48T	Neutral	0.001
NPHS1	O60500-1.1	S48V	Neutral	0.002
NPHS1	O60500-1.1	S48W	Neutral	0.023
NPHS1	O60500-1.1	S48Y	Neutral	0.003
NPHS1	O60500-1.1	V49A	Pathogenic	0.73
NPHS1	O60500-1.1	V49C	Neutral	0.298
NPHS1	O60500-1.1	V49D	Pathogenic	0.697
NPHS1	O60500-1.1	V49E	Pathogenic	0.69
NPHS1	O60500-1.1	V49F	Neutral	0.476
NPHS1	O60500-1.1	V49G	Pathogenic	0.669
NPHS1	O60500-1.1	V49H	Neutral	0.37
NPHS1	O60500-1.1	V49I	Pathogenic	0.78
NPHS1	O60500-1.1	V49K	Pathogenic	0.874
NPHS1	O60500-1.1	V49L	Pathogenic	0.577
NPHS1	O60500-1.1	V49M	Neutral	0.405
NPHS1	O60500-1.1	V49N	Pathogenic	0.614
NPHS1	O60500-1.1	V49P	Neutral	0.277
NPHS1	O60500-1.1	V49Q	Pathogenic	0.573
NPHS1	O60500-1.1	V49R	Pathogenic	0.866
NPHS1	O60500-1.1	V49S	Pathogenic	0.638
NPHS1	O60500-1.1	V49T	Pathogenic	0.612
NPHS1	O60500-1.1	V49W	Pathogenic	0.611
NPHS1	O60500-1.1	V49Y	Neutral	0.396
NPHS1	O60500-1.1	E50A	Neutral	0.154
NPHS1	O60500-1.1	E50C	Neutral	0.087
NPHS1	O60500-1.1	E50D	Neutral	0.093
NPHS1	O60500-1.1	E50F	Neutral	0.337
NPHS1	O60500-1.1	E50G	Neutral	0.108
NPHS1	O60500-1.1	E50H	Neutral	0.088
NPHS1	O60500-1.1	E50I	Neutral	0.286
NPHS1	O60500-1.1	E50K	Neutral	0.103
NPHS1	O60500-1.1	E50L	Neutral	0.256
NPHS1	O60500-1.1	E50M	Neutral	0.203
NPHS1	O60500-1.1	E50N	Neutral	0.034
NPHS1	O60500-1.1	E50P	Neutral	0.163
NPHS1	O60500-1.1	E50Q	Neutral	0.103
NPHS1	O60500-1.1	E50R	Neutral	0.097
NPHS1	O60500-1.1	E50S	Neutral	0.124
NPHS1	O60500-1.1	E50T	Neutral	0.084
NPHS1	O60500-1.1	E50V	Neutral	0.162
NPHS1	O60500-1.1	E50W	Pathogenic	0.662
NPHS1	O60500-1.1	E50Y	Neutral	0.203
NPHS1	O60500-1.1	L51A	Pathogenic	0.986
NPHS1	O60500-1.1	L51C	Pathogenic	0.943
NPHS1	O60500-1.1	L51D	Pathogenic	0.984
NPHS1	O60500-1.1	L51E	Pathogenic	0.98
NPHS1	O60500-1.1	L51F	Pathogenic	0.836
NPHS1	O60500-1.1	L51G	Pathogenic	0.981
NPHS1	O60500-1.1	L51H	Pathogenic	0.925
NPHS1	O60500-1.1	L51I	Pathogenic	0.899
NPHS1	O60500-1.1	L51K	Pathogenic	0.991
NPHS1	O60500-1.1	L51M	Pathogenic	0.939
NPHS1	O60500-1.1	L51N	Pathogenic	0.984
NPHS1	O60500-1.1	L51P	Pathogenic	0.909
NPHS1	O60500-1.1	L51Q	Pathogenic	0.972
NPHS1	O60500-1.1	L51R	Pathogenic	0.993
NPHS1	O60500-1.1	L51S	Pathogenic	0.986
NPHS1	O60500-1.1	L51T	Pathogenic	0.976
NPHS1	O60500-1.1	L51V	Pathogenic	0.943
NPHS1	O60500-1.1	L51W	Pathogenic	0.898
NPHS1	O60500-1.1	L51Y	Pathogenic	0.912
NPHS1	O60500-1.1	R52A	Neutral	0.174
NPHS1	O60500-1.1	R52C	Neutral	0.141
NPHS1	O60500-1.1	R52D	Neutral	0.016
NPHS1	O60500-1.1	R52E	Neutral	0.028
NPHS1	O60500-1.1	R52F	Neutral	0.147
NPHS1	O60500-1.1	R52G	Neutral	0.123
NPHS1	O60500-1.1	R52H	Neutral	0.067
NPHS1	O60500-1.1	R52I	Neutral	0.185
NPHS1	O60500-1.1	R52K	Neutral	0.02
NPHS1	O60500-1.1	R52L	Neutral	0.226
NPHS1	O60500-1.1	R52M	Neutral	0.178
NPHS1	O60500-1.1	R52N	Neutral	0.039
NPHS1	O60500-1.1	R52P	Neutral	0.131
NPHS1	O60500-1.1	R52Q	Neutral	0.066
NPHS1	O60500-1.1	R52S	Neutral	0.098
NPHS1	O60500-1.1	R52T	Neutral	0.095
NPHS1	O60500-1.1	R52V	Neutral	0.13
NPHS1	O60500-1.1	R52W	Neutral	0.264
NPHS1	O60500-1.1	R52Y	Neutral	0.061
NPHS1	O60500-1.1	C53A	Pathogenic	0.98
NPHS1	O60500-1.1	C53D	Pathogenic	0.981
NPHS1	O60500-1.1	C53E	Pathogenic	0.978
NPHS1	O60500-1.1	C53F	Pathogenic	0.982
NPHS1	O60500-1.1	C53G	Pathogenic	0.973
NPHS1	O60500-1.1	C53H	Pathogenic	0.963
NPHS1	O60500-1.1	C53I	Pathogenic	0.984
NPHS1	O60500-1.1	C53K	Pathogenic	0.995
NPHS1	O60500-1.1	C53L	Pathogenic	0.982
NPHS1	O60500-1.1	C53M	Pathogenic	0.964
NPHS1	O60500-1.1	C53N	Pathogenic	0.979
NPHS1	O60500-1.1	C53P	Pathogenic	0.847
NPHS1	O60500-1.1	C53Q	Pathogenic	0.975
NPHS1	O60500-1.1	C53R	Pathogenic	0.996
NPHS1	O60500-1.1	C53S	Pathogenic	0.979
NPHS1	O60500-1.1	C53T	Pathogenic	0.963
NPHS1	O60500-1.1	C53V	Pathogenic	0.944
NPHS1	O60500-1.1	C53W	Pathogenic	0.995
NPHS1	O60500-1.1	C53Y	Pathogenic	0.951
NPHS1	O60500-1.1	G54A	Neutral	0.181
NPHS1	O60500-1.1	G54C	Neutral	0.221
NPHS1	O60500-1.1	G54D	Neutral	0.341
NPHS1	O60500-1.1	G54E	Neutral	0.304
NPHS1	O60500-1.1	G54F	Pathogenic	0.75
NPHS1	O60500-1.1	G54H	Neutral	0.203
NPHS1	O60500-1.1	G54I	Pathogenic	0.614
NPHS1	O60500-1.1	G54K	Pathogenic	0.577
NPHS1	O60500-1.1	G54L	Pathogenic	0.577
NPHS1	O60500-1.1	G54M	Pathogenic	0.503
NPHS1	O60500-1.1	G54N	Neutral	0.404
NPHS1	O60500-1.1	G54P	Neutral	0.239
NPHS1	O60500-1.1	G54Q	Neutral	0.209
NPHS1	O60500-1.1	G54R	Pathogenic	0.655
NPHS1	O60500-1.1	G54S	Neutral	0.145
NPHS1	O60500-1.1	G54T	Neutral	0.145
NPHS1	O60500-1.1	G54V	Neutral	0.387
NPHS1	O60500-1.1	G54W	Pathogenic	0.945
NPHS1	O60500-1.1	G54Y	Pathogenic	0.502
NPHS1	O60500-1.1	V55A	Pathogenic	0.992
NPHS1	O60500-1.1	V55C	Pathogenic	0.948
NPHS1	O60500-1.1	V55D	Pathogenic	0.99
NPHS1	O60500-1.1	V55E	Pathogenic	0.99
NPHS1	O60500-1.1	V55F	Pathogenic	0.975
NPHS1	O60500-1.1	V55G	Pathogenic	0.989
NPHS1	O60500-1.1	V55H	Pathogenic	0.962
NPHS1	O60500-1.1	V55I	Pathogenic	0.994
NPHS1	O60500-1.1	V55K	Pathogenic	0.997
NPHS1	O60500-1.1	V55L	Pathogenic	0.983
NPHS1	O60500-1.1	V55M	Pathogenic	0.967
NPHS1	O60500-1.1	V55N	Pathogenic	0.986
NPHS1	O60500-1.1	V55P	Pathogenic	0.943
NPHS1	O60500-1.1	V55Q	Pathogenic	0.983
NPHS1	O60500-1.1	V55R	Pathogenic	0.996
NPHS1	O60500-1.1	V55S	Pathogenic	0.987
NPHS1	O60500-1.1	V55T	Pathogenic	0.986
NPHS1	O60500-1.1	V55W	Pathogenic	0.985
NPHS1	O60500-1.1	V55Y	Pathogenic	0.966
NPHS1	O60500-1.1	S56A	Neutral	0.01
NPHS1	O60500-1.1	S56C	Neutral	0.014
NPHS1	O60500-1.1	S56D	Neutral	0.015
NPHS1	O60500-1.1	S56E	Neutral	0.019
NPHS1	O60500-1.1	S56F	Neutral	0.092
NPHS1	O60500-1.1	S56G	Neutral	0.006
NPHS1	O60500-1.1	S56H	Neutral	0.008
NPHS1	O60500-1.1	S56I	Neutral	0.074
NPHS1	O60500-1.1	S56K	Neutral	0.058
NPHS1	O60500-1.1	S56L	Neutral	0.064
NPHS1	O60500-1.1	S56M	Neutral	0.048
NPHS1	O60500-1.1	S56N	Neutral	0.02
NPHS1	O60500-1.1	S56P	Neutral	0.01
NPHS1	O60500-1.1	S56Q	Neutral	0.012
NPHS1	O60500-1.1	S56R	Neutral	0.054
NPHS1	O60500-1.1	S56T	Neutral	0.013
NPHS1	O60500-1.1	S56V	Neutral	0.021
NPHS1	O60500-1.1	S56W	Neutral	0.207
NPHS1	O60500-1.1	S56Y	Neutral	0.033
NPHS1	O60500-1.1	T57A	Neutral	0.002
NPHS1	O60500-1.1	T57C	Neutral	0.002
NPHS1	O60500-1.1	T57D	Neutral	0.003
NPHS1	O60500-1.1	T57E	Neutral	0.003
NPHS1	O60500-1.1	T57F	Neutral	0.011
NPHS1	O60500-1.1	T57G	Neutral	0.002
NPHS1	O60500-1.1	T57H	Neutral	0.001
NPHS1	O60500-1.1	T57I	Neutral	0.013
NPHS1	O60500-1.1	T57K	Neutral	0.011
NPHS1	O60500-1.1	T57L	Neutral	0.011
NPHS1	O60500-1.1	T57M	Neutral	0.006
NPHS1	O60500-1.1	T57N	Neutral	0.004
NPHS1	O60500-1.1	T57P	Neutral	0.001
NPHS1	O60500-1.1	T57Q	Neutral	0.002
NPHS1	O60500-1.1	T57R	Neutral	0.015
NPHS1	O60500-1.1	T57S	Neutral	0.003
NPHS1	O60500-1.1	T57V	Neutral	0.005
NPHS1	O60500-1.1	T57W	Neutral	0.041
NPHS1	O60500-1.1	T57Y	Neutral	0.004
NPHS1	O60500-1.1	P58A	Pathogenic	0.738
NPHS1	O60500-1.1	P58C	Neutral	0.393
NPHS1	O60500-1.1	P58D	Pathogenic	0.893
NPHS1	O60500-1.1	P58E	Pathogenic	0.913
NPHS1	O60500-1.1	P58F	Pathogenic	0.792
NPHS1	O60500-1.1	P58G	Pathogenic	0.824
NPHS1	O60500-1.1	P58H	Pathogenic	0.734
NPHS1	O60500-1.1	P58I	Pathogenic	0.817
NPHS1	O60500-1.1	P58K	Pathogenic	0.97
NPHS1	O60500-1.1	P58L	Pathogenic	0.793
NPHS1	O60500-1.1	P58M	Pathogenic	0.74
NPHS1	O60500-1.1	P58N	Pathogenic	0.83
NPHS1	O60500-1.1	P58Q	Pathogenic	0.863
NPHS1	O60500-1.1	P58R	Pathogenic	0.968
NPHS1	O60500-1.1	P58S	Pathogenic	0.803
NPHS1	O60500-1.1	P58T	Pathogenic	0.654
NPHS1	O60500-1.1	P58V	Pathogenic	0.64
NPHS1	O60500-1.1	P58W	Pathogenic	0.936
NPHS1	O60500-1.1	P58Y	Pathogenic	0.656
NPHS1	O60500-1.1	G59A	Neutral	0.174
NPHS1	O60500-1.1	G59C	Neutral	0.213
NPHS1	O60500-1.1	G59D	Neutral	0.331
NPHS1	O60500-1.1	G59E	Neutral	0.294
NPHS1	O60500-1.1	G59F	Pathogenic	0.741
NPHS1	O60500-1.1	G59H	Neutral	0.196
NPHS1	O60500-1.1	G59I	Pathogenic	0.602
NPHS1	O60500-1.1	G59K	Pathogenic	0.566
NPHS1	O60500-1.1	G59L	Pathogenic	0.565
NPHS1	O60500-1.1	G59M	Neutral	0.491
NPHS1	O60500-1.1	G59N	Neutral	0.393
NPHS1	O60500-1.1	G59P	Neutral	0.231
NPHS1	O60500-1.1	G59Q	Neutral	0.201
NPHS1	O60500-1.1	G59R	Pathogenic	0.644
NPHS1	O60500-1.1	G59S	Neutral	0.139
NPHS1	O60500-1.1	G59T	Neutral	0.139
NPHS1	O60500-1.1	G59V	Neutral	0.376
NPHS1	O60500-1.1	G59W	Pathogenic	0.943
NPHS1	O60500-1.1	G59Y	Neutral	0.491
NPHS1	O60500-1.1	S60A	Pathogenic	0.668
NPHS1	O60500-1.1	S60C	Pathogenic	0.744
NPHS1	O60500-1.1	S60D	Pathogenic	0.761
NPHS1	O60500-1.1	S60E	Pathogenic	0.8
NPHS1	O60500-1.1	S60F	Pathogenic	0.954
NPHS1	O60500-1.1	S60G	Pathogenic	0.572
NPHS1	O60500-1.1	S60H	Pathogenic	0.636
NPHS1	O60500-1.1	S60I	Pathogenic	0.942
NPHS1	O60500-1.1	S60K	Pathogenic	0.926
NPHS1	O60500-1.1	S60L	Pathogenic	0.933
NPHS1	O60500-1.1	S60M	Pathogenic	0.912
NPHS1	O60500-1.1	S60N	Pathogenic	0.806
NPHS1	O60500-1.1	S60P	Pathogenic	0.683
NPHS1	O60500-1.1	S60Q	Pathogenic	0.708
NPHS1	O60500-1.1	S60R	Pathogenic	0.921
NPHS1	O60500-1.1	S60T	Pathogenic	0.721
NPHS1	O60500-1.1	S60V	Pathogenic	0.812
NPHS1	O60500-1.1	S60W	Pathogenic	0.982
NPHS1	O60500-1.1	S60Y	Pathogenic	0.874
NPHS1	O60500-1.1	A61C	Neutral	0.009
NPHS1	O60500-1.1	A61D	Neutral	0.009
NPHS1	O60500-1.1	A61E	Neutral	0.016
NPHS1	O60500-1.1	A61F	Neutral	0.042
NPHS1	O60500-1.1	A61G	Neutral	0.005
NPHS1	O60500-1.1	A61H	Neutral	0.004
NPHS1	O60500-1.1	A61I	Neutral	0.049
NPHS1	O60500-1.1	A61K	Neutral	0.048
NPHS1	O60500-1.1	A61L	Neutral	0.043
NPHS1	O60500-1.1	A61M	Neutral	0.022
NPHS1	O60500-1.1	A61N	Neutral	0.007
NPHS1	O60500-1.1	A61P	Neutral	0.005
NPHS1	O60500-1.1	A61Q	Neutral	0.01
NPHS1	O60500-1.1	A61R	Neutral	0.065
NPHS1	O60500-1.1	A61S	Neutral	0.006
NPHS1	O60500-1.1	A61T	Neutral	0.004
NPHS1	O60500-1.1	A61V	Neutral	0.02
NPHS1	O60500-1.1	A61W	Neutral	0.103
NPHS1	O60500-1.1	A61Y	Neutral	0.015
NPHS1	O60500-1.1	V62A	Pathogenic	0.992
NPHS1	O60500-1.1	V62C	Pathogenic	0.949
NPHS1	O60500-1.1	V62D	Pathogenic	0.99
NPHS1	O60500-1.1	V62E	Pathogenic	0.99
NPHS1	O60500-1.1	V62F	Pathogenic	0.976
NPHS1	O60500-1.1	V62G	Pathogenic	0.989
NPHS1	O60500-1.1	V62H	Pathogenic	0.963
NPHS1	O60500-1.1	V62I	Pathogenic	0.994
NPHS1	O60500-1.1	V62K	Pathogenic	0.997
NPHS1	O60500-1.1	V62L	Pathogenic	0.984
NPHS1	O60500-1.1	V62M	Pathogenic	0.968
NPHS1	O60500-1.1	V62N	Pathogenic	0.986
NPHS1	O60500-1.1	V62P	Pathogenic	0.944
NPHS1	O60500-1.1	V62Q	Pathogenic	0.983
NPHS1	O60500-1.1	V62R	Pathogenic	0.997
NPHS1	O60500-1.1	V62S	Pathogenic	0.987
NPHS1	O60500-1.1	V62T	Pathogenic	0.986
NPHS1	O60500-1.1	V62W	Pathogenic	0.986
NPHS1	O60500-1.1	V62Y	Pathogenic	0.967
NPHS1	O60500-1.1	Q63A	Pathogenic	0.997
NPHS1	O60500-1.1	Q63C	Pathogenic	0.996
NPHS1	O60500-1.1	Q63D	Pathogenic	0.996
NPHS1	O60500-1.1	Q63E	Pathogenic	0.997
NPHS1	O60500-1.1	Q63F	Pathogenic	0.998
NPHS1	O60500-1.1	Q63G	Pathogenic	0.995
NPHS1	O60500-1.1	Q63H	Pathogenic	0.992
NPHS1	O60500-1.1	Q63I	Pathogenic	0.998
NPHS1	O60500-1.1	Q63K	Pathogenic	0.998
NPHS1	O60500-1.1	Q63L	Pathogenic	0.998
NPHS1	O60500-1.1	Q63M	Pathogenic	0.999
NPHS1	O60500-1.1	Q63N	Pathogenic	0.994
NPHS1	O60500-1.1	Q63P	Pathogenic	0.997
NPHS1	O60500-1.1	Q63R	Pathogenic	0.999
NPHS1	O60500-1.1	Q63S	Pathogenic	0.996
NPHS1	O60500-1.1	Q63T	Pathogenic	0.993
NPHS1	O60500-1.1	Q63V	Pathogenic	0.997
NPHS1	O60500-1.1	Q63W	Pathogenic	1.0
NPHS1	O60500-1.1	Q63Y	Pathogenic	0.998
NPHS1	O60500-1.1	W64A	Pathogenic	1.0
NPHS1	O60500-1.1	W64C	Pathogenic	1.0
NPHS1	O60500-1.1	W64D	Pathogenic	1.0
NPHS1	O60500-1.1	W64E	Pathogenic	1.0
NPHS1	O60500-1.1	W64F	Pathogenic	0.999
NPHS1	O60500-1.1	W64G	Pathogenic	1.0
NPHS1	O60500-1.1	W64H	Pathogenic	1.0
NPHS1	O60500-1.1	W64I	Pathogenic	0.997
NPHS1	O60500-1.1	W64K	Pathogenic	1.0
NPHS1	O60500-1.1	W64L	Pathogenic	0.998
NPHS1	O60500-1.1	W64M	Pathogenic	0.999
NPHS1	O60500-1.1	W64N	Pathogenic	1.0
NPHS1	O60500-1.1	W64P	Pathogenic	1.0
NPHS1	O60500-1.1	W64Q	Pathogenic	1.0
NPHS1	O60500-1.1	W64R	Pathogenic	1.0
NPHS1	O60500-1.1	W64S	Pathogenic	1.0
NPHS1	O60500-1.1	W64T	Pathogenic	1.0
NPHS1	O60500-1.1	W64V	Pathogenic	0.999
NPHS1	O60500-1.1	W64Y	Pathogenic	1.0
NPHS1	O60500-1.1	A65C	Pathogenic	0.639
NPHS1	O60500-1.1	A65D	Pathogenic	0.62
NPHS1	O60500-1.1	A65E	Pathogenic	0.753
NPHS1	O60500-1.1	A65F	Pathogenic	0.894
NPHS1	O60500-1.1	A65G	Pathogenic	0.506
NPHS1	O60500-1.1	A65H	Neutral	0.446
NPHS1	O60500-1.1	A65I	Pathogenic	0.908
NPHS1	O60500-1.1	A65K	Pathogenic	0.905
NPHS1	O60500-1.1	A65L	Pathogenic	0.894
NPHS1	O60500-1.1	A65M	Pathogenic	0.808
NPHS1	O60500-1.1	A65N	Pathogenic	0.588
NPHS1	O60500-1.1	A65P	Neutral	0.468
NPHS1	O60500-1.1	A65Q	Pathogenic	0.649
NPHS1	O60500-1.1	A65R	Pathogenic	0.93
NPHS1	O60500-1.1	A65S	Pathogenic	0.543
NPHS1	O60500-1.1	A65T	Neutral	0.452
NPHS1	O60500-1.1	A65V	Pathogenic	0.797
NPHS1	O60500-1.1	A65W	Pathogenic	0.956
NPHS1	O60500-1.1	A65Y	Pathogenic	0.738
NPHS1	O60500-1.1	K66A	Pathogenic	1.0
NPHS1	O60500-1.1	K66C	Pathogenic	1.0
NPHS1	O60500-1.1	K66D	Pathogenic	0.997
NPHS1	O60500-1.1	K66E	Pathogenic	0.999
NPHS1	O60500-1.1	K66F	Pathogenic	1.0
NPHS1	O60500-1.1	K66G	Pathogenic	1.0
NPHS1	O60500-1.1	K66H	Pathogenic	0.999
NPHS1	O60500-1.1	K66I	Pathogenic	1.0
NPHS1	O60500-1.1	K66L	Pathogenic	1.0
NPHS1	O60500-1.1	K66M	Pathogenic	1.0
NPHS1	O60500-1.1	K66N	Pathogenic	0.998
NPHS1	O60500-1.1	K66P	Pathogenic	1.0
NPHS1	O60500-1.1	K66Q	Pathogenic	0.999
NPHS1	O60500-1.1	K66R	Pathogenic	0.998
NPHS1	O60500-1.1	K66S	Pathogenic	1.0
NPHS1	O60500-1.1	K66T	Pathogenic	0.999
NPHS1	O60500-1.1	K66V	Pathogenic	1.0
NPHS1	O60500-1.1	K66W	Pathogenic	1.0
NPHS1	O60500-1.1	K66Y	Pathogenic	0.999
NPHS1	O60500-1.1	D67A	Pathogenic	0.96
NPHS1	O60500-1.1	D67C	Pathogenic	0.966
NPHS1	O60500-1.1	D67E	Pathogenic	0.962
NPHS1	O60500-1.1	D67F	Pathogenic	0.996
NPHS1	O60500-1.1	D67G	Pathogenic	0.973
NPHS1	O60500-1.1	D67H	Pathogenic	0.968
NPHS1	O60500-1.1	D67I	Pathogenic	0.995
NPHS1	O60500-1.1	D67K	Pathogenic	0.942
NPHS1	O60500-1.1	D67L	Pathogenic	0.991
NPHS1	O60500-1.1	D67M	Pathogenic	0.988
NPHS1	O60500-1.1	D67N	Pathogenic	0.93
NPHS1	O60500-1.1	D67P	Pathogenic	0.975
NPHS1	O60500-1.1	D67Q	Pathogenic	0.96
NPHS1	O60500-1.1	D67R	Pathogenic	0.938
NPHS1	O60500-1.1	D67S	Pathogenic	0.966
NPHS1	O60500-1.1	D67T	Pathogenic	0.952
NPHS1	O60500-1.1	D67V	Pathogenic	0.98
NPHS1	O60500-1.1	D67W	Pathogenic	0.998
NPHS1	O60500-1.1	D67Y	Pathogenic	0.988
NPHS1	O60500-1.1	G68A	Pathogenic	0.98
NPHS1	O60500-1.1	G68C	Pathogenic	0.984
NPHS1	O60500-1.1	G68D	Pathogenic	0.991
NPHS1	O60500-1.1	G68E	Pathogenic	0.99
NPHS1	O60500-1.1	G68F	Pathogenic	0.998
NPHS1	O60500-1.1	G68H	Pathogenic	0.982
NPHS1	O60500-1.1	G68I	Pathogenic	0.997
NPHS1	O60500-1.1	G68K	Pathogenic	0.997
NPHS1	O60500-1.1	G68L	Pathogenic	0.997
NPHS1	O60500-1.1	G68M	Pathogenic	0.996
NPHS1	O60500-1.1	G68N	Pathogenic	0.993
NPHS1	O60500-1.1	G68P	Pathogenic	0.986
NPHS1	O60500-1.1	G68Q	Pathogenic	0.983
NPHS1	O60500-1.1	G68R	Pathogenic	0.998
NPHS1	O60500-1.1	G68S	Pathogenic	0.974
NPHS1	O60500-1.1	G68T	Pathogenic	0.974
NPHS1	O60500-1.1	G68V	Pathogenic	0.993
NPHS1	O60500-1.1	G68W	Pathogenic	1.0
NPHS1	O60500-1.1	G68Y	Pathogenic	0.995
NPHS1	O60500-1.1	L69A	Pathogenic	0.986
NPHS1	O60500-1.1	L69C	Pathogenic	0.944
NPHS1	O60500-1.1	L69D	Pathogenic	0.984
NPHS1	O60500-1.1	L69E	Pathogenic	0.98
NPHS1	O60500-1.1	L69F	Pathogenic	0.84
NPHS1	O60500-1.1	L69G	Pathogenic	0.982
NPHS1	O60500-1.1	L69H	Pathogenic	0.927
NPHS1	O60500-1.1	L69I	Pathogenic	0.902
NPHS1	O60500-1.1	L69K	Pathogenic	0.991
NPHS1	O60500-1.1	L69M	Pathogenic	0.941
NPHS1	O60500-1.1	L69N	Pathogenic	0.985
NPHS1	O60500-1.1	L69P	Pathogenic	0.911
NPHS1	O60500-1.1	L69Q	Pathogenic	0.972
NPHS1	O60500-1.1	L69R	Pathogenic	0.994
NPHS1	O60500-1.1	L69S	Pathogenic	0.986
NPHS1	O60500-1.1	L69T	Pathogenic	0.977
NPHS1	O60500-1.1	L69V	Pathogenic	0.944
NPHS1	O60500-1.1	L69W	Pathogenic	0.901
NPHS1	O60500-1.1	L69Y	Pathogenic	0.914
NPHS1	O60500-1.1	L70A	Pathogenic	0.983
NPHS1	O60500-1.1	L70C	Pathogenic	0.93
NPHS1	O60500-1.1	L70D	Pathogenic	0.98
NPHS1	O60500-1.1	L70E	Pathogenic	0.975
NPHS1	O60500-1.1	L70F	Pathogenic	0.804
NPHS1	O60500-1.1	L70G	Pathogenic	0.977
NPHS1	O60500-1.1	L70H	Pathogenic	0.909
NPHS1	O60500-1.1	L70I	Pathogenic	0.878
NPHS1	O60500-1.1	L70K	Pathogenic	0.989
NPHS1	O60500-1.1	L70M	Pathogenic	0.925
NPHS1	O60500-1.1	L70N	Pathogenic	0.98
NPHS1	O60500-1.1	L70P	Pathogenic	0.889
NPHS1	O60500-1.1	L70Q	Pathogenic	0.965
NPHS1	O60500-1.1	L70R	Pathogenic	0.992
NPHS1	O60500-1.1	L70S	Pathogenic	0.982
NPHS1	O60500-1.1	L70T	Pathogenic	0.971
NPHS1	O60500-1.1	L70V	Pathogenic	0.93
NPHS1	O60500-1.1	L70W	Pathogenic	0.876
NPHS1	O60500-1.1	L70Y	Pathogenic	0.893
NPHS1	O60500-1.1	L71A	Pathogenic	0.996
NPHS1	O60500-1.1	L71C	Pathogenic	0.982
NPHS1	O60500-1.1	L71D	Pathogenic	0.995
NPHS1	O60500-1.1	L71E	Pathogenic	0.994
NPHS1	O60500-1.1	L71F	Pathogenic	0.943
NPHS1	O60500-1.1	L71G	Pathogenic	0.994
NPHS1	O60500-1.1	L71H	Pathogenic	0.976
NPHS1	O60500-1.1	L71I	Pathogenic	0.967
NPHS1	O60500-1.1	L71K	Pathogenic	0.997
NPHS1	O60500-1.1	L71M	Pathogenic	0.98
NPHS1	O60500-1.1	L71N	Pathogenic	0.995
NPHS1	O60500-1.1	L71P	Pathogenic	0.97
NPHS1	O60500-1.1	L71Q	Pathogenic	0.991
NPHS1	O60500-1.1	L71R	Pathogenic	0.998
NPHS1	O60500-1.1	L71S	Pathogenic	0.996
NPHS1	O60500-1.1	L71T	Pathogenic	0.993
NPHS1	O60500-1.1	L71V	Pathogenic	0.982
NPHS1	O60500-1.1	L71W	Pathogenic	0.966
NPHS1	O60500-1.1	L71Y	Pathogenic	0.971
NPHS1	O60500-1.1	G72A	Pathogenic	0.974
NPHS1	O60500-1.1	G72C	Pathogenic	0.979
NPHS1	O60500-1.1	G72D	Pathogenic	0.989
NPHS1	O60500-1.1	G72E	Pathogenic	0.987
NPHS1	O60500-1.1	G72F	Pathogenic	0.998
NPHS1	O60500-1.1	G72H	Pathogenic	0.977
NPHS1	O60500-1.1	G72I	Pathogenic	0.996
NPHS1	O60500-1.1	G72K	Pathogenic	0.996
NPHS1	O60500-1.1	G72L	Pathogenic	0.996
NPHS1	O60500-1.1	G72M	Pathogenic	0.994
NPHS1	O60500-1.1	G72N	Pathogenic	0.991
NPHS1	O60500-1.1	G72P	Pathogenic	0.981
NPHS1	O60500-1.1	G72Q	Pathogenic	0.978
NPHS1	O60500-1.1	G72R	Pathogenic	0.997
NPHS1	O60500-1.1	G72S	Pathogenic	0.966
NPHS1	O60500-1.1	G72T	Pathogenic	0.966
NPHS1	O60500-1.1	G72V	Pathogenic	0.991
NPHS1	O60500-1.1	G72W	Pathogenic	1.0
NPHS1	O60500-1.1	G72Y	Pathogenic	0.994
NPHS1	O60500-1.1	P73A	Pathogenic	0.977
NPHS1	O60500-1.1	P73C	Pathogenic	0.909
NPHS1	O60500-1.1	P73D	Pathogenic	0.992
NPHS1	O60500-1.1	P73E	Pathogenic	0.994
NPHS1	O60500-1.1	P73F	Pathogenic	0.983
NPHS1	O60500-1.1	P73G	Pathogenic	0.986
NPHS1	O60500-1.1	P73H	Pathogenic	0.977
NPHS1	O60500-1.1	P73I	Pathogenic	0.986
NPHS1	O60500-1.1	P73K	Pathogenic	0.998
NPHS1	O60500-1.1	P73L	Pathogenic	0.983
NPHS1	O60500-1.1	P73M	Pathogenic	0.978
NPHS1	O60500-1.1	P73N	Pathogenic	0.987
NPHS1	O60500-1.1	P73Q	Pathogenic	0.99
NPHS1	O60500-1.1	P73R	Pathogenic	0.998
NPHS1	O60500-1.1	P73S	Pathogenic	0.984
NPHS1	O60500-1.1	P73T	Pathogenic	0.967
NPHS1	O60500-1.1	P73V	Pathogenic	0.965
NPHS1	O60500-1.1	P73W	Pathogenic	0.996
NPHS1	O60500-1.1	P73Y	Pathogenic	0.967
NPHS1	O60500-1.1	D74A	Pathogenic	0.531
NPHS1	O60500-1.1	D74C	Pathogenic	0.569
NPHS1	O60500-1.1	D74E	Pathogenic	0.543
NPHS1	O60500-1.1	D74F	Pathogenic	0.917
NPHS1	O60500-1.1	D74G	Pathogenic	0.626
NPHS1	O60500-1.1	D74H	Pathogenic	0.582
NPHS1	O60500-1.1	D74I	Pathogenic	0.897
NPHS1	O60500-1.1	D74K	Neutral	0.43
NPHS1	O60500-1.1	D74L	Pathogenic	0.833
NPHS1	O60500-1.1	D74M	Pathogenic	0.788
NPHS1	O60500-1.1	D74N	Neutral	0.383
NPHS1	O60500-1.1	D74P	Pathogenic	0.644
NPHS1	O60500-1.1	D74Q	Pathogenic	0.529
NPHS1	O60500-1.1	D74R	Neutral	0.413
NPHS1	O60500-1.1	D74S	Pathogenic	0.567
NPHS1	O60500-1.1	D74T	Neutral	0.482
NPHS1	O60500-1.1	D74V	Pathogenic	0.699
NPHS1	O60500-1.1	D74W	Pathogenic	0.966
NPHS1	O60500-1.1	D74Y	Pathogenic	0.787
NPHS1	O60500-1.1	P75A	Neutral	0.211
NPHS1	O60500-1.1	P75C	Neutral	0.058
NPHS1	O60500-1.1	P75D	Neutral	0.442
NPHS1	O60500-1.1	P75E	Neutral	0.499
NPHS1	O60500-1.1	P75F	Neutral	0.266
NPHS1	O60500-1.1	P75G	Neutral	0.308
NPHS1	O60500-1.1	P75H	Neutral	0.208
NPHS1	O60500-1.1	P75I	Neutral	0.299
NPHS1	O60500-1.1	P75K	Pathogenic	0.756
NPHS1	O60500-1.1	P75L	Neutral	0.268
NPHS1	O60500-1.1	P75M	Neutral	0.213
NPHS1	O60500-1.1	P75N	Neutral	0.317
NPHS1	O60500-1.1	P75Q	Neutral	0.375
NPHS1	O60500-1.1	P75R	Pathogenic	0.743
NPHS1	O60500-1.1	P75S	Neutral	0.279
NPHS1	O60500-1.1	P75T	Neutral	0.153
NPHS1	O60500-1.1	P75V	Neutral	0.145
NPHS1	O60500-1.1	P75W	Pathogenic	0.583
NPHS1	O60500-1.1	P75Y	Neutral	0.154
NPHS1	O60500-1.1	R76A	Neutral	0.365
NPHS1	O60500-1.1	R76C	Neutral	0.31
NPHS1	O60500-1.1	R76D	Neutral	0.042
NPHS1	O60500-1.1	R76E	Neutral	0.072
NPHS1	O60500-1.1	R76F	Neutral	0.319
NPHS1	O60500-1.1	R76G	Neutral	0.276
NPHS1	O60500-1.1	R76H	Neutral	0.165
NPHS1	O60500-1.1	R76I	Neutral	0.383
NPHS1	O60500-1.1	R76K	Neutral	0.052
NPHS1	O60500-1.1	R76L	Neutral	0.443
NPHS1	O60500-1.1	R76M	Neutral	0.371
NPHS1	O60500-1.1	R76N	Neutral	0.1
NPHS1	O60500-1.1	R76P	Neutral	0.292
NPHS1	O60500-1.1	R76Q	Neutral	0.161
NPHS1	O60500-1.1	R76S	Neutral	0.23
NPHS1	O60500-1.1	R76T	Neutral	0.223
NPHS1	O60500-1.1	R76V	Neutral	0.289
NPHS1	O60500-1.1	R76W	Neutral	0.494
NPHS1	O60500-1.1	R76Y	Neutral	0.15
NPHS1	O60500-1.1	I77A	Pathogenic	0.989
NPHS1	O60500-1.1	I77C	Pathogenic	0.954
NPHS1	O60500-1.1	I77D	Pathogenic	0.991
NPHS1	O60500-1.1	I77E	Pathogenic	0.984
NPHS1	O60500-1.1	I77F	Pathogenic	0.832
NPHS1	O60500-1.1	I77G	Pathogenic	0.985
NPHS1	O60500-1.1	I77H	Pathogenic	0.94
NPHS1	O60500-1.1	I77K	Pathogenic	0.989
NPHS1	O60500-1.1	I77L	Pathogenic	0.906
NPHS1	O60500-1.1	I77M	Pathogenic	0.929
NPHS1	O60500-1.1	I77N	Pathogenic	0.987
NPHS1	O60500-1.1	I77P	Pathogenic	0.927
NPHS1	O60500-1.1	I77Q	Pathogenic	0.967
NPHS1	O60500-1.1	I77R	Pathogenic	0.992
NPHS1	O60500-1.1	I77S	Pathogenic	0.989
NPHS1	O60500-1.1	I77T	Pathogenic	0.981
NPHS1	O60500-1.1	I77V	Pathogenic	0.979
NPHS1	O60500-1.1	I77W	Pathogenic	0.846
NPHS1	O60500-1.1	I77Y	Pathogenic	0.929
NPHS1	O60500-1.1	P78A	Pathogenic	0.973
NPHS1	O60500-1.1	P78C	Pathogenic	0.892
NPHS1	O60500-1.1	P78D	Pathogenic	0.991
NPHS1	O60500-1.1	P78E	Pathogenic	0.993
NPHS1	O60500-1.1	P78F	Pathogenic	0.98
NPHS1	O60500-1.1	P78G	Pathogenic	0.983
NPHS1	O60500-1.1	P78H	Pathogenic	0.972
NPHS1	O60500-1.1	P78I	Pathogenic	0.983
NPHS1	O60500-1.1	P78K	Pathogenic	0.998
NPHS1	O60500-1.1	P78L	Pathogenic	0.98
NPHS1	O60500-1.1	P78M	Pathogenic	0.973
NPHS1	O60500-1.1	P78N	Pathogenic	0.984
NPHS1	O60500-1.1	P78Q	Pathogenic	0.988
NPHS1	O60500-1.1	P78R	Pathogenic	0.997
NPHS1	O60500-1.1	P78S	Pathogenic	0.981
NPHS1	O60500-1.1	P78T	Pathogenic	0.96
NPHS1	O60500-1.1	P78V	Pathogenic	0.958
NPHS1	O60500-1.1	P78W	Pathogenic	0.995
NPHS1	O60500-1.1	P78Y	Pathogenic	0.96
NPHS1	O60500-1.1	G79A	Pathogenic	0.601
NPHS1	O60500-1.1	G79C	Pathogenic	0.66
NPHS1	O60500-1.1	G79D	Pathogenic	0.78
NPHS1	O60500-1.1	G79E	Pathogenic	0.749
NPHS1	O60500-1.1	G79F	Pathogenic	0.953
NPHS1	O60500-1.1	G79H	Pathogenic	0.635
NPHS1	O60500-1.1	G79I	Pathogenic	0.916
NPHS1	O60500-1.1	G79K	Pathogenic	0.903
NPHS1	O60500-1.1	G79L	Pathogenic	0.903
NPHS1	O60500-1.1	G79M	Pathogenic	0.873
NPHS1	O60500-1.1	G79N	Pathogenic	0.822
NPHS1	O60500-1.1	G79P	Pathogenic	0.682
NPHS1	O60500-1.1	G79Q	Pathogenic	0.643
NPHS1	O60500-1.1	G79R	Pathogenic	0.928
NPHS1	O60500-1.1	G79S	Pathogenic	0.537
NPHS1	O60500-1.1	G79T	Pathogenic	0.537
NPHS1	O60500-1.1	G79V	Pathogenic	0.812
NPHS1	O60500-1.1	G79W	Pathogenic	0.992
NPHS1	O60500-1.1	G79Y	Pathogenic	0.873
NPHS1	O60500-1.1	F80A	Pathogenic	1.0
NPHS1	O60500-1.1	F80C	Pathogenic	0.999
NPHS1	O60500-1.1	F80D	Pathogenic	1.0
NPHS1	O60500-1.1	F80E	Pathogenic	1.0
NPHS1	O60500-1.1	F80G	Pathogenic	1.0
NPHS1	O60500-1.1	F80H	Pathogenic	0.999
NPHS1	O60500-1.1	F80I	Pathogenic	0.995
NPHS1	O60500-1.1	F80K	Pathogenic	1.0
NPHS1	O60500-1.1	F80L	Pathogenic	0.996
NPHS1	O60500-1.1	F80M	Pathogenic	0.998
NPHS1	O60500-1.1	F80N	Pathogenic	1.0
NPHS1	O60500-1.1	F80P	Pathogenic	0.998
NPHS1	O60500-1.1	F80Q	Pathogenic	0.999
NPHS1	O60500-1.1	F80R	Pathogenic	1.0
NPHS1	O60500-1.1	F80S	Pathogenic	1.0
NPHS1	O60500-1.1	F80T	Pathogenic	0.999
NPHS1	O60500-1.1	F80V	Pathogenic	0.998
NPHS1	O60500-1.1	F80W	Pathogenic	0.999
NPHS1	O60500-1.1	F80Y	Pathogenic	1.0
NPHS1	O60500-1.1	P81A	Pathogenic	0.9
NPHS1	O60500-1.1	P81C	Pathogenic	0.674
NPHS1	O60500-1.1	P81D	Pathogenic	0.964
NPHS1	O60500-1.1	P81E	Pathogenic	0.971
NPHS1	O60500-1.1	P81F	Pathogenic	0.924
NPHS1	O60500-1.1	P81G	Pathogenic	0.937
NPHS1	O60500-1.1	P81H	Pathogenic	0.898
NPHS1	O60500-1.1	P81I	Pathogenic	0.934
NPHS1	O60500-1.1	P81K	Pathogenic	0.99
NPHS1	O60500-1.1	P81L	Pathogenic	0.925
NPHS1	O60500-1.1	P81M	Pathogenic	0.901
NPHS1	O60500-1.1	P81N	Pathogenic	0.94
NPHS1	O60500-1.1	P81Q	Pathogenic	0.953
NPHS1	O60500-1.1	P81R	Pathogenic	0.99
NPHS1	O60500-1.1	P81S	Pathogenic	0.929
NPHS1	O60500-1.1	P81T	Pathogenic	0.858
NPHS1	O60500-1.1	P81V	Pathogenic	0.85
NPHS1	O60500-1.1	P81W	Pathogenic	0.979
NPHS1	O60500-1.1	P81Y	Pathogenic	0.859
NPHS1	O60500-1.1	R82A	Pathogenic	0.999
NPHS1	O60500-1.1	R82C	Pathogenic	0.999
NPHS1	O60500-1.1	R82D	Pathogenic	0.986
NPHS1	O60500-1.1	R82E	Pathogenic	0.992
NPHS1	O60500-1.1	R82F	Pathogenic	0.999
NPHS1	O60500-1.1	R82G	Pathogenic	0.998
NPHS1	O60500-1.1	R82H	Pathogenic	0.997
NPHS1	O60500-1.1	R82I	Pathogenic	0.999
NPHS1	O60500-1.1	R82K	Pathogenic	0.989
NPHS1	O60500-1.1	R82L	Pathogenic	0.999
NPHS1	O60500-1.1	R82M	Pathogenic	0.999
NPHS1	O60500-1.1	R82N	Pathogenic	0.994
NPHS1	O60500-1.1	R82P	Pathogenic	0.998
NPHS1	O60500-1.1	R82Q	Pathogenic	0.997
NPHS1	O60500-1.1	R82S	Pathogenic	0.998
NPHS1	O60500-1.1	R82T	Pathogenic	0.998
NPHS1	O60500-1.1	R82V	Pathogenic	0.998
NPHS1	O60500-1.1	R82W	Pathogenic	0.999
NPHS1	O60500-1.1	R82Y	Pathogenic	0.996
NPHS1	O60500-1.1	Y83A	Pathogenic	0.999
NPHS1	O60500-1.1	Y83C	Pathogenic	0.997
NPHS1	O60500-1.1	Y83D	Pathogenic	1.0
NPHS1	O60500-1.1	Y83E	Pathogenic	1.0
NPHS1	O60500-1.1	Y83F	Pathogenic	1.0
NPHS1	O60500-1.1	Y83G	Pathogenic	1.0
NPHS1	O60500-1.1	Y83H	Pathogenic	1.0
NPHS1	O60500-1.1	Y83I	Pathogenic	0.999
NPHS1	O60500-1.1	Y83K	Pathogenic	1.0
NPHS1	O60500-1.1	Y83L	Pathogenic	0.998
NPHS1	O60500-1.1	Y83M	Pathogenic	0.997
NPHS1	O60500-1.1	Y83N	Pathogenic	1.0
NPHS1	O60500-1.1	Y83P	Pathogenic	0.997
NPHS1	O60500-1.1	Y83Q	Pathogenic	0.999
NPHS1	O60500-1.1	Y83R	Pathogenic	1.0
NPHS1	O60500-1.1	Y83S	Pathogenic	1.0
NPHS1	O60500-1.1	Y83T	Pathogenic	0.999
NPHS1	O60500-1.1	Y83V	Pathogenic	0.998
NPHS1	O60500-1.1	Y83W	Pathogenic	1.0
NPHS1	O60500-1.1	R84A	Pathogenic	0.801
NPHS1	O60500-1.1	R84C	Pathogenic	0.759
NPHS1	O60500-1.1	R84D	Neutral	0.235
NPHS1	O60500-1.1	R84E	Neutral	0.352
NPHS1	O60500-1.1	R84F	Pathogenic	0.767
NPHS1	O60500-1.1	R84G	Pathogenic	0.728
NPHS1	O60500-1.1	R84H	Pathogenic	0.581
NPHS1	O60500-1.1	R84I	Pathogenic	0.813
NPHS1	O60500-1.1	R84K	Neutral	0.28
NPHS1	O60500-1.1	R84L	Pathogenic	0.848
NPHS1	O60500-1.1	R84M	Pathogenic	0.805
NPHS1	O60500-1.1	R84N	Neutral	0.439
NPHS1	O60500-1.1	R84P	Pathogenic	0.743
NPHS1	O60500-1.1	R84Q	Pathogenic	0.573
NPHS1	O60500-1.1	R84S	Pathogenic	0.676
NPHS1	O60500-1.1	R84T	Pathogenic	0.668
NPHS1	O60500-1.1	R84V	Pathogenic	0.74
NPHS1	O60500-1.1	R84W	Pathogenic	0.873
NPHS1	O60500-1.1	R84Y	Pathogenic	0.554
NPHS1	O60500-1.1	L85A	Pathogenic	0.875
NPHS1	O60500-1.1	L85C	Pathogenic	0.621
NPHS1	O60500-1.1	L85D	Pathogenic	0.856
NPHS1	O60500-1.1	L85E	Pathogenic	0.826
NPHS1	O60500-1.1	L85F	Neutral	0.335
NPHS1	O60500-1.1	L85G	Pathogenic	0.839
NPHS1	O60500-1.1	L85H	Pathogenic	0.55
NPHS1	O60500-1.1	L85I	Neutral	0.469
NPHS1	O60500-1.1	L85K	Pathogenic	0.916
NPHS1	O60500-1.1	L85M	Pathogenic	0.604
NPHS1	O60500-1.1	L85N	Pathogenic	0.86
NPHS1	O60500-1.1	L85P	Neutral	0.498
NPHS1	O60500-1.1	L85Q	Pathogenic	0.772
NPHS1	O60500-1.1	L85R	Pathogenic	0.938
NPHS1	O60500-1.1	L85S	Pathogenic	0.872
NPHS1	O60500-1.1	L85T	Pathogenic	0.803
NPHS1	O60500-1.1	L85V	Pathogenic	0.621
NPHS1	O60500-1.1	L85W	Neutral	0.466
NPHS1	O60500-1.1	L85Y	Pathogenic	0.507
NPHS1	O60500-1.1	E86A	Neutral	0.202
NPHS1	O60500-1.1	E86C	Neutral	0.117
NPHS1	O60500-1.1	E86D	Neutral	0.124
NPHS1	O60500-1.1	E86F	Neutral	0.414
NPHS1	O60500-1.1	E86G	Neutral	0.144
NPHS1	O60500-1.1	E86H	Neutral	0.118
NPHS1	O60500-1.1	E86I	Neutral	0.358
NPHS1	O60500-1.1	E86K	Neutral	0.138
NPHS1	O60500-1.1	E86L	Neutral	0.324
NPHS1	O60500-1.1	E86M	Neutral	0.262
NPHS1	O60500-1.1	E86N	Neutral	0.047
NPHS1	O60500-1.1	E86P	Neutral	0.213
NPHS1	O60500-1.1	E86Q	Neutral	0.138
NPHS1	O60500-1.1	E86R	Neutral	0.129
NPHS1	O60500-1.1	E86S	Neutral	0.164
NPHS1	O60500-1.1	E86T	Neutral	0.113
NPHS1	O60500-1.1	E86V	Neutral	0.211
NPHS1	O60500-1.1	E86W	Pathogenic	0.732
NPHS1	O60500-1.1	E86Y	Neutral	0.262
NPHS1	O60500-1.1	G87A	Pathogenic	0.974
NPHS1	O60500-1.1	G87C	Pathogenic	0.98
NPHS1	O60500-1.1	G87D	Pathogenic	0.989
NPHS1	O60500-1.1	G87E	Pathogenic	0.987
NPHS1	O60500-1.1	G87F	Pathogenic	0.998
NPHS1	O60500-1.1	G87H	Pathogenic	0.978
NPHS1	O60500-1.1	G87I	Pathogenic	0.996
NPHS1	O60500-1.1	G87K	Pathogenic	0.996
NPHS1	O60500-1.1	G87L	Pathogenic	0.996
NPHS1	O60500-1.1	G87M	Pathogenic	0.994
NPHS1	O60500-1.1	G87N	Pathogenic	0.991
NPHS1	O60500-1.1	G87P	Pathogenic	0.982
NPHS1	O60500-1.1	G87Q	Pathogenic	0.978
NPHS1	O60500-1.1	G87R	Pathogenic	0.997
NPHS1	O60500-1.1	G87S	Pathogenic	0.967
NPHS1	O60500-1.1	G87T	Pathogenic	0.967
NPHS1	O60500-1.1	G87V	Pathogenic	0.991
NPHS1	O60500-1.1	G87W	Pathogenic	1.0
NPHS1	O60500-1.1	G87Y	Pathogenic	0.994
NPHS1	O60500-1.1	D88A	Pathogenic	0.969
NPHS1	O60500-1.1	D88C	Pathogenic	0.973
NPHS1	O60500-1.1	D88E	Pathogenic	0.971
NPHS1	O60500-1.1	D88F	Pathogenic	0.997
NPHS1	O60500-1.1	D88G	Pathogenic	0.979
NPHS1	O60500-1.1	D88H	Pathogenic	0.975
NPHS1	O60500-1.1	D88I	Pathogenic	0.996
NPHS1	O60500-1.1	D88K	Pathogenic	0.955
NPHS1	O60500-1.1	D88L	Pathogenic	0.993
NPHS1	O60500-1.1	D88M	Pathogenic	0.99
NPHS1	O60500-1.1	D88N	Pathogenic	0.945
NPHS1	O60500-1.1	D88P	Pathogenic	0.98
NPHS1	O60500-1.1	D88Q	Pathogenic	0.969
NPHS1	O60500-1.1	D88R	Pathogenic	0.951
NPHS1	O60500-1.1	D88S	Pathogenic	0.973
NPHS1	O60500-1.1	D88T	Pathogenic	0.963
NPHS1	O60500-1.1	D88V	Pathogenic	0.985
NPHS1	O60500-1.1	D88W	Pathogenic	0.999
NPHS1	O60500-1.1	D88Y	Pathogenic	0.99
NPHS1	O60500-1.1	P89A	Neutral	0.469
NPHS1	O60500-1.1	P89C	Neutral	0.169
NPHS1	O60500-1.1	P89D	Pathogenic	0.723
NPHS1	O60500-1.1	P89E	Pathogenic	0.766
NPHS1	O60500-1.1	P89F	Pathogenic	0.544
NPHS1	O60500-1.1	P89G	Pathogenic	0.594
NPHS1	O60500-1.1	P89H	Neutral	0.464
NPHS1	O60500-1.1	P89I	Pathogenic	0.584
NPHS1	O60500-1.1	P89K	Pathogenic	0.911
NPHS1	O60500-1.1	P89L	Pathogenic	0.546
NPHS1	O60500-1.1	P89M	Neutral	0.472
NPHS1	O60500-1.1	P89N	Pathogenic	0.605
NPHS1	O60500-1.1	P89Q	Pathogenic	0.665
NPHS1	O60500-1.1	P89R	Pathogenic	0.905
NPHS1	O60500-1.1	P89S	Pathogenic	0.561
NPHS1	O60500-1.1	P89T	Neutral	0.372
NPHS1	O60500-1.1	P89V	Neutral	0.358
NPHS1	O60500-1.1	P89W	Pathogenic	0.821
NPHS1	O60500-1.1	P89Y	Neutral	0.374
NPHS1	O60500-1.1	A90C	Neutral	0.022
NPHS1	O60500-1.1	A90D	Neutral	0.02
NPHS1	O60500-1.1	A90E	Neutral	0.037
NPHS1	O60500-1.1	A90F	Neutral	0.096
NPHS1	O60500-1.1	A90G	Neutral	0.013
NPHS1	O60500-1.1	A90H	Neutral	0.01
NPHS1	O60500-1.1	A90I	Neutral	0.111
NPHS1	O60500-1.1	A90K	Neutral	0.107
NPHS1	O60500-1.1	A90L	Neutral	0.097
NPHS1	O60500-1.1	A90M	Neutral	0.051
NPHS1	O60500-1.1	A90N	Neutral	0.018
NPHS1	O60500-1.1	A90P	Neutral	0.011
NPHS1	O60500-1.1	A90Q	Neutral	0.023
NPHS1	O60500-1.1	A90R	Neutral	0.143
NPHS1	O60500-1.1	A90S	Neutral	0.015
NPHS1	O60500-1.1	A90T	Neutral	0.01
NPHS1	O60500-1.1	A90V	Neutral	0.047
NPHS1	O60500-1.1	A90W	Neutral	0.215
NPHS1	O60500-1.1	A90Y	Neutral	0.034
NPHS1	O60500-1.1	R91A	Pathogenic	0.862
NPHS1	O60500-1.1	R91C	Pathogenic	0.831
NPHS1	O60500-1.1	R91D	Neutral	0.324
NPHS1	O60500-1.1	R91E	Neutral	0.459
NPHS1	O60500-1.1	R91F	Pathogenic	0.837
NPHS1	O60500-1.1	R91G	Pathogenic	0.806
NPHS1	O60500-1.1	R91H	Pathogenic	0.683
NPHS1	O60500-1.1	R91I	Pathogenic	0.871
NPHS1	O60500-1.1	R91K	Neutral	0.377
NPHS1	O60500-1.1	R91L	Pathogenic	0.897
NPHS1	O60500-1.1	R91M	Pathogenic	0.866
NPHS1	O60500-1.1	R91N	Pathogenic	0.549
NPHS1	O60500-1.1	R91P	Pathogenic	0.818
NPHS1	O60500-1.1	R91Q	Pathogenic	0.677
NPHS1	O60500-1.1	R91S	Pathogenic	0.765
NPHS1	O60500-1.1	R91T	Pathogenic	0.758
NPHS1	O60500-1.1	R91V	Pathogenic	0.816
NPHS1	O60500-1.1	R91W	Pathogenic	0.914
NPHS1	O60500-1.1	R91Y	Pathogenic	0.659
NPHS1	O60500-1.1	G92A	Pathogenic	0.976
NPHS1	O60500-1.1	G92C	Pathogenic	0.982
NPHS1	O60500-1.1	G92D	Pathogenic	0.99
NPHS1	O60500-1.1	G92E	Pathogenic	0.988
NPHS1	O60500-1.1	G92F	Pathogenic	0.998
NPHS1	O60500-1.1	G92H	Pathogenic	0.979
NPHS1	O60500-1.1	G92I	Pathogenic	0.997
NPHS1	O60500-1.1	G92K	Pathogenic	0.996
NPHS1	O60500-1.1	G92L	Pathogenic	0.996
NPHS1	O60500-1.1	G92M	Pathogenic	0.995
NPHS1	O60500-1.1	G92N	Pathogenic	0.992
NPHS1	O60500-1.1	G92P	Pathogenic	0.983
NPHS1	O60500-1.1	G92Q	Pathogenic	0.98
NPHS1	O60500-1.1	G92R	Pathogenic	0.997
NPHS1	O60500-1.1	G92S	Pathogenic	0.969
NPHS1	O60500-1.1	G92T	Pathogenic	0.97
NPHS1	O60500-1.1	G92V	Pathogenic	0.992
NPHS1	O60500-1.1	G92W	Pathogenic	1.0
NPHS1	O60500-1.1	G92Y	Pathogenic	0.995
NPHS1	O60500-1.1	E93A	Pathogenic	0.888
NPHS1	O60500-1.1	E93C	Pathogenic	0.806
NPHS1	O60500-1.1	E93D	Pathogenic	0.816
NPHS1	O60500-1.1	E93F	Pathogenic	0.957
NPHS1	O60500-1.1	E93G	Pathogenic	0.84
NPHS1	O60500-1.1	E93H	Pathogenic	0.806
NPHS1	O60500-1.1	E93I	Pathogenic	0.946
NPHS1	O60500-1.1	E93K	Pathogenic	0.833
NPHS1	O60500-1.1	E93L	Pathogenic	0.937
NPHS1	O60500-1.1	E93M	Pathogenic	0.917
NPHS1	O60500-1.1	E93N	Pathogenic	0.606
NPHS1	O60500-1.1	E93P	Pathogenic	0.894
NPHS1	O60500-1.1	E93Q	Pathogenic	0.833
NPHS1	O60500-1.1	E93R	Pathogenic	0.823
NPHS1	O60500-1.1	E93S	Pathogenic	0.86
NPHS1	O60500-1.1	E93T	Pathogenic	0.799
NPHS1	O60500-1.1	E93V	Pathogenic	0.893
NPHS1	O60500-1.1	E93W	Pathogenic	0.988
NPHS1	O60500-1.1	E93Y	Pathogenic	0.917
NPHS1	O60500-1.1	F94A	Pathogenic	0.972
NPHS1	O60500-1.1	F94C	Pathogenic	0.891
NPHS1	O60500-1.1	F94D	Pathogenic	0.985
NPHS1	O60500-1.1	F94E	Pathogenic	0.973
NPHS1	O60500-1.1	F94G	Pathogenic	0.983
NPHS1	O60500-1.1	F94H	Pathogenic	0.953
NPHS1	O60500-1.1	F94I	Pathogenic	0.696
NPHS1	O60500-1.1	F94K	Pathogenic	0.97
NPHS1	O60500-1.1	F94L	Pathogenic	0.719
NPHS1	O60500-1.1	F94M	Pathogenic	0.837
NPHS1	O60500-1.1	F94N	Pathogenic	0.979
NPHS1	O60500-1.1	F94P	Pathogenic	0.833
NPHS1	O60500-1.1	F94Q	Pathogenic	0.944
NPHS1	O60500-1.1	F94R	Pathogenic	0.978
NPHS1	O60500-1.1	F94S	Pathogenic	0.981
NPHS1	O60500-1.1	F94T	Pathogenic	0.954
NPHS1	O60500-1.1	F94V	Pathogenic	0.847
NPHS1	O60500-1.1	F94W	Pathogenic	0.909
NPHS1	O60500-1.1	F94Y	Pathogenic	0.958
NPHS1	O60500-1.1	H95A	Pathogenic	0.952
NPHS1	O60500-1.1	H95C	Pathogenic	0.958
NPHS1	O60500-1.1	H95D	Pathogenic	0.98
NPHS1	O60500-1.1	H95E	Pathogenic	0.975
NPHS1	O60500-1.1	H95F	Pathogenic	0.992
NPHS1	O60500-1.1	H95G	Pathogenic	0.967
NPHS1	O60500-1.1	H95I	Pathogenic	0.977
NPHS1	O60500-1.1	H95K	Pathogenic	0.982
NPHS1	O60500-1.1	H95L	Pathogenic	0.973
NPHS1	O60500-1.1	H95M	Pathogenic	0.964
NPHS1	O60500-1.1	H95N	Pathogenic	0.987
NPHS1	O60500-1.1	H95P	Pathogenic	0.955
NPHS1	O60500-1.1	H95Q	Pathogenic	0.949
NPHS1	O60500-1.1	H95R	Pathogenic	0.991
NPHS1	O60500-1.1	H95S	Pathogenic	0.962
NPHS1	O60500-1.1	H95T	Pathogenic	0.908
NPHS1	O60500-1.1	H95V	Pathogenic	0.954
NPHS1	O60500-1.1	H95W	Pathogenic	0.997
NPHS1	O60500-1.1	H95Y	Pathogenic	0.993
NPHS1	O60500-1.1	L96A	Pathogenic	0.995
NPHS1	O60500-1.1	L96C	Pathogenic	0.979
NPHS1	O60500-1.1	L96D	Pathogenic	0.994
NPHS1	O60500-1.1	L96E	Pathogenic	0.993
NPHS1	O60500-1.1	L96F	Pathogenic	0.934
NPHS1	O60500-1.1	L96G	Pathogenic	0.993
NPHS1	O60500-1.1	L96H	Pathogenic	0.972
NPHS1	O60500-1.1	L96I	Pathogenic	0.961
NPHS1	O60500-1.1	L96K	Pathogenic	0.997
NPHS1	O60500-1.1	L96M	Pathogenic	0.977
NPHS1	O60500-1.1	L96N	Pathogenic	0.994
NPHS1	O60500-1.1	L96P	Pathogenic	0.965
NPHS1	O60500-1.1	L96Q	Pathogenic	0.99
NPHS1	O60500-1.1	L96R	Pathogenic	0.998
NPHS1	O60500-1.1	L96S	Pathogenic	0.995
NPHS1	O60500-1.1	L96T	Pathogenic	0.991
NPHS1	O60500-1.1	L96V	Pathogenic	0.979
NPHS1	O60500-1.1	L96W	Pathogenic	0.961
NPHS1	O60500-1.1	L96Y	Pathogenic	0.966
NPHS1	O60500-1.1	H97A	Neutral	0.41
NPHS1	O60500-1.1	H97C	Neutral	0.448
NPHS1	O60500-1.1	H97D	Pathogenic	0.633
NPHS1	O60500-1.1	H97E	Pathogenic	0.581
NPHS1	O60500-1.1	H97F	Pathogenic	0.808
NPHS1	O60500-1.1	H97G	Pathogenic	0.504
NPHS1	O60500-1.1	H97I	Pathogenic	0.598
NPHS1	O60500-1.1	H97K	Pathogenic	0.654
NPHS1	O60500-1.1	H97L	Pathogenic	0.561
NPHS1	O60500-1.1	H97M	Neutral	0.486
NPHS1	O60500-1.1	H97N	Pathogenic	0.727
NPHS1	O60500-1.1	H97P	Neutral	0.426
NPHS1	O60500-1.1	H97Q	Neutral	0.398
NPHS1	O60500-1.1	H97R	Pathogenic	0.797
NPHS1	O60500-1.1	H97S	Neutral	0.47
NPHS1	O60500-1.1	H97T	Neutral	0.258
NPHS1	O60500-1.1	H97V	Neutral	0.423
NPHS1	O60500-1.1	H97W	Pathogenic	0.916
NPHS1	O60500-1.1	H97Y	Pathogenic	0.824
NPHS1	O60500-1.1	I98A	Pathogenic	0.999
NPHS1	O60500-1.1	I98C	Pathogenic	0.995
NPHS1	O60500-1.1	I98D	Pathogenic	0.999
NPHS1	O60500-1.1	I98E	Pathogenic	0.998
NPHS1	O60500-1.1	I98F	Pathogenic	0.98
NPHS1	O60500-1.1	I98G	Pathogenic	0.998
NPHS1	O60500-1.1	I98H	Pathogenic	0.994
NPHS1	O60500-1.1	I98K	Pathogenic	0.999
NPHS1	O60500-1.1	I98L	Pathogenic	0.99
NPHS1	O60500-1.1	I98M	Pathogenic	0.992
NPHS1	O60500-1.1	I98N	Pathogenic	0.999
NPHS1	O60500-1.1	I98P	Pathogenic	0.992
NPHS1	O60500-1.1	I98Q	Pathogenic	0.997
NPHS1	O60500-1.1	I98R	Pathogenic	0.999
NPHS1	O60500-1.1	I98S	Pathogenic	0.999
NPHS1	O60500-1.1	I98T	Pathogenic	0.998
NPHS1	O60500-1.1	I98V	Pathogenic	0.998
NPHS1	O60500-1.1	I98W	Pathogenic	0.982
NPHS1	O60500-1.1	I98Y	Pathogenic	0.992
NPHS1	O60500-1.1	E99A	Pathogenic	0.569
NPHS1	O60500-1.1	E99C	Neutral	0.409
NPHS1	O60500-1.1	E99D	Neutral	0.425
NPHS1	O60500-1.1	E99F	Pathogenic	0.786
NPHS1	O60500-1.1	E99G	Neutral	0.467
NPHS1	O60500-1.1	E99H	Neutral	0.41
NPHS1	O60500-1.1	E99I	Pathogenic	0.744
NPHS1	O60500-1.1	E99K	Neutral	0.454
NPHS1	O60500-1.1	E99L	Pathogenic	0.714
NPHS1	O60500-1.1	E99M	Pathogenic	0.649
NPHS1	O60500-1.1	E99N	Neutral	0.204
NPHS1	O60500-1.1	E99P	Pathogenic	0.585
NPHS1	O60500-1.1	E99Q	Neutral	0.454
NPHS1	O60500-1.1	E99R	Neutral	0.436
NPHS1	O60500-1.1	E99S	Pathogenic	0.506
NPHS1	O60500-1.1	E99T	Neutral	0.398
NPHS1	O60500-1.1	E99V	Pathogenic	0.582
NPHS1	O60500-1.1	E99W	Pathogenic	0.934
NPHS1	O60500-1.1	E99Y	Pathogenic	0.649
NPHS1	O60500-1.1	A100C	Neutral	0.035
NPHS1	O60500-1.1	A100D	Neutral	0.032
NPHS1	O60500-1.1	A100E	Neutral	0.059
NPHS1	O60500-1.1	A100F	Neutral	0.147
NPHS1	O60500-1.1	A100G	Neutral	0.021
NPHS1	O60500-1.1	A100H	Neutral	0.016
NPHS1	O60500-1.1	A100I	Neutral	0.168
NPHS1	O60500-1.1	A100K	Neutral	0.164
NPHS1	O60500-1.1	A100L	Neutral	0.148
NPHS1	O60500-1.1	A100M	Neutral	0.08
NPHS1	O60500-1.1	A100N	Neutral	0.028
NPHS1	O60500-1.1	A100P	Neutral	0.018
NPHS1	O60500-1.1	A100Q	Neutral	0.036
NPHS1	O60500-1.1	A100R	Neutral	0.214
NPHS1	O60500-1.1	A100S	Neutral	0.024
NPHS1	O60500-1.1	A100T	Neutral	0.017
NPHS1	O60500-1.1	A100V	Neutral	0.074
NPHS1	O60500-1.1	A100W	Neutral	0.308
NPHS1	O60500-1.1	A100Y	Neutral	0.055
NPHS1	O60500-1.1	C101A	Pathogenic	0.863
NPHS1	O60500-1.1	C101D	Pathogenic	0.872
NPHS1	O60500-1.1	C101E	Pathogenic	0.851
NPHS1	O60500-1.1	C101F	Pathogenic	0.875
NPHS1	O60500-1.1	C101G	Pathogenic	0.825
NPHS1	O60500-1.1	C101H	Pathogenic	0.771
NPHS1	O60500-1.1	C101I	Pathogenic	0.892
NPHS1	O60500-1.1	C101K	Pathogenic	0.964
NPHS1	O60500-1.1	C101L	Pathogenic	0.876
NPHS1	O60500-1.1	C101M	Pathogenic	0.779
NPHS1	O60500-1.1	C101N	Pathogenic	0.856
NPHS1	O60500-1.1	C101P	Neutral	0.42
NPHS1	O60500-1.1	C101Q	Pathogenic	0.838
NPHS1	O60500-1.1	C101R	Pathogenic	0.974
NPHS1	O60500-1.1	C101S	Pathogenic	0.86
NPHS1	O60500-1.1	C101T	Pathogenic	0.775
NPHS1	O60500-1.1	C101V	Pathogenic	0.687
NPHS1	O60500-1.1	C101W	Pathogenic	0.964
NPHS1	O60500-1.1	C101Y	Pathogenic	0.715
NPHS1	O60500-1.1	D102A	Neutral	0.328
NPHS1	O60500-1.1	D102C	Neutral	0.363
NPHS1	O60500-1.1	D102E	Neutral	0.339
NPHS1	O60500-1.1	D102F	Pathogenic	0.826
NPHS1	O60500-1.1	D102G	Neutral	0.419
NPHS1	O60500-1.1	D102H	Neutral	0.375
NPHS1	O60500-1.1	D102I	Pathogenic	0.789
NPHS1	O60500-1.1	D102K	Neutral	0.246
NPHS1	O60500-1.1	D102L	Pathogenic	0.683
NPHS1	O60500-1.1	D102M	Pathogenic	0.615
NPHS1	O60500-1.1	D102N	Neutral	0.211
NPHS1	O60500-1.1	D102P	Neutral	0.438
NPHS1	O60500-1.1	D102Q	Neutral	0.326
NPHS1	O60500-1.1	D102R	Neutral	0.233
NPHS1	O60500-1.1	D102S	Neutral	0.361
NPHS1	O60500-1.1	D102T	Neutral	0.286
NPHS1	O60500-1.1	D102V	Neutral	0.5
NPHS1	O60500-1.1	D102W	Pathogenic	0.925
NPHS1	O60500-1.1	D102Y	Pathogenic	0.615
NPHS1	O60500-1.1	L103A	Pathogenic	0.992
NPHS1	O60500-1.1	L103C	Pathogenic	0.966
NPHS1	O60500-1.1	L103D	Pathogenic	0.991
NPHS1	O60500-1.1	L103E	Pathogenic	0.988
NPHS1	O60500-1.1	L103F	Pathogenic	0.899
NPHS1	O60500-1.1	L103G	Pathogenic	0.989
NPHS1	O60500-1.1	L103H	Pathogenic	0.956
NPHS1	O60500-1.1	L103I	Pathogenic	0.94
NPHS1	O60500-1.1	L103K	Pathogenic	0.995
NPHS1	O60500-1.1	L103M	Pathogenic	0.964
NPHS1	O60500-1.1	L103N	Pathogenic	0.991
NPHS1	O60500-1.1	L103P	Pathogenic	0.946
NPHS1	O60500-1.1	L103Q	Pathogenic	0.983
NPHS1	O60500-1.1	L103R	Pathogenic	0.996
NPHS1	O60500-1.1	L103S	Pathogenic	0.992
NPHS1	O60500-1.1	L103T	Pathogenic	0.986
NPHS1	O60500-1.1	L103V	Pathogenic	0.966
NPHS1	O60500-1.1	L103W	Pathogenic	0.939
NPHS1	O60500-1.1	L103Y	Pathogenic	0.948
NPHS1	O60500-1.1	S104A	Neutral	0.207
NPHS1	O60500-1.1	S104C	Neutral	0.274
NPHS1	O60500-1.1	S104D	Neutral	0.293
NPHS1	O60500-1.1	S104E	Neutral	0.342
NPHS1	O60500-1.1	S104F	Pathogenic	0.728
NPHS1	O60500-1.1	S104G	Neutral	0.148
NPHS1	O60500-1.1	S104H	Neutral	0.185
NPHS1	O60500-1.1	S104I	Pathogenic	0.678
NPHS1	O60500-1.1	S104K	Pathogenic	0.619
NPHS1	O60500-1.1	S104L	Pathogenic	0.644
NPHS1	O60500-1.1	S104M	Pathogenic	0.573
NPHS1	O60500-1.1	S104N	Neutral	0.351
NPHS1	O60500-1.1	S104P	Neutral	0.219
NPHS1	O60500-1.1	S104Q	Neutral	0.239
NPHS1	O60500-1.1	S104R	Pathogenic	0.602
NPHS1	O60500-1.1	S104T	Neutral	0.252
NPHS1	O60500-1.1	S104V	Neutral	0.36
NPHS1	O60500-1.1	S104W	Pathogenic	0.874
NPHS1	O60500-1.1	S104Y	Neutral	0.473
NPHS1	O60500-1.1	D105A	Pathogenic	0.995
NPHS1	O60500-1.1	D105C	Pathogenic	0.996
NPHS1	O60500-1.1	D105E	Pathogenic	0.995
NPHS1	O60500-1.1	D105F	Pathogenic	0.999
NPHS1	O60500-1.1	D105G	Pathogenic	0.997
NPHS1	O60500-1.1	D105H	Pathogenic	0.996
NPHS1	O60500-1.1	D105I	Pathogenic	0.999
NPHS1	O60500-1.1	D105K	Pathogenic	0.992
NPHS1	O60500-1.1	D105L	Pathogenic	0.999
NPHS1	O60500-1.1	D105M	Pathogenic	0.998
NPHS1	O60500-1.1	D105N	Pathogenic	0.991
NPHS1	O60500-1.1	D105P	Pathogenic	0.997
NPHS1	O60500-1.1	D105Q	Pathogenic	0.995
NPHS1	O60500-1.1	D105R	Pathogenic	0.992
NPHS1	O60500-1.1	D105S	Pathogenic	0.996
NPHS1	O60500-1.1	D105T	Pathogenic	0.994
NPHS1	O60500-1.1	D105V	Pathogenic	0.997
NPHS1	O60500-1.1	D105W	Pathogenic	1.0
NPHS1	O60500-1.1	D105Y	Pathogenic	0.998
NPHS1	O60500-1.1	D106A	Pathogenic	0.995
NPHS1	O60500-1.1	D106C	Pathogenic	0.996
NPHS1	O60500-1.1	D106E	Pathogenic	0.995
NPHS1	O60500-1.1	D106F	Pathogenic	0.999
NPHS1	O60500-1.1	D106G	Pathogenic	0.997
NPHS1	O60500-1.1	D106H	Pathogenic	0.996
NPHS1	O60500-1.1	D106I	Pathogenic	0.999
NPHS1	O60500-1.1	D106K	Pathogenic	0.992
NPHS1	O60500-1.1	D106L	Pathogenic	0.999
NPHS1	O60500-1.1	D106M	Pathogenic	0.998
NPHS1	O60500-1.1	D106N	Pathogenic	0.991
NPHS1	O60500-1.1	D106P	Pathogenic	0.997
NPHS1	O60500-1.1	D106Q	Pathogenic	0.995
NPHS1	O60500-1.1	D106R	Pathogenic	0.992
NPHS1	O60500-1.1	D106S	Pathogenic	0.996
NPHS1	O60500-1.1	D106T	Pathogenic	0.994
NPHS1	O60500-1.1	D106V	Pathogenic	0.997
NPHS1	O60500-1.1	D106W	Pathogenic	1.0
NPHS1	O60500-1.1	D106Y	Pathogenic	0.998
NPHS1	O60500-1.1	A107C	Pathogenic	0.752
NPHS1	O60500-1.1	A107D	Pathogenic	0.736
NPHS1	O60500-1.1	A107E	Pathogenic	0.84
NPHS1	O60500-1.1	A107F	Pathogenic	0.935
NPHS1	O60500-1.1	A107G	Pathogenic	0.637
NPHS1	O60500-1.1	A107H	Pathogenic	0.58
NPHS1	O60500-1.1	A107I	Pathogenic	0.944
NPHS1	O60500-1.1	A107K	Pathogenic	0.942
NPHS1	O60500-1.1	A107L	Pathogenic	0.936
NPHS1	O60500-1.1	A107M	Pathogenic	0.878
NPHS1	O60500-1.1	A107N	Pathogenic	0.71
NPHS1	O60500-1.1	A107P	Pathogenic	0.601
NPHS1	O60500-1.1	A107Q	Pathogenic	0.76
NPHS1	O60500-1.1	A107R	Pathogenic	0.958
NPHS1	O60500-1.1	A107S	Pathogenic	0.67
NPHS1	O60500-1.1	A107T	Pathogenic	0.586
NPHS1	O60500-1.1	A107V	Pathogenic	0.871
NPHS1	O60500-1.1	A107W	Pathogenic	0.974
NPHS1	O60500-1.1	A107Y	Pathogenic	0.829
NPHS1	O60500-1.1	E108A	Neutral	0.136
NPHS1	O60500-1.1	E108C	Neutral	0.076
NPHS1	O60500-1.1	E108D	Neutral	0.081
NPHS1	O60500-1.1	E108F	Neutral	0.305
NPHS1	O60500-1.1	E108G	Neutral	0.095
NPHS1	O60500-1.1	E108H	Neutral	0.077
NPHS1	O60500-1.1	E108I	Neutral	0.257
NPHS1	O60500-1.1	E108K	Neutral	0.09
NPHS1	O60500-1.1	E108L	Neutral	0.229
NPHS1	O60500-1.1	E108M	Neutral	0.181
NPHS1	O60500-1.1	E108N	Neutral	0.03
NPHS1	O60500-1.1	E108P	Neutral	0.144
NPHS1	O60500-1.1	E108Q	Neutral	0.09
NPHS1	O60500-1.1	E108R	Neutral	0.085
NPHS1	O60500-1.1	E108S	Neutral	0.109
NPHS1	O60500-1.1	E108T	Neutral	0.073
NPHS1	O60500-1.1	E108V	Neutral	0.143
NPHS1	O60500-1.1	E108W	Pathogenic	0.629
NPHS1	O60500-1.1	E108Y	Neutral	0.18
NPHS1	O60500-1.1	Y109A	Pathogenic	0.997
NPHS1	O60500-1.1	Y109C	Pathogenic	0.987
NPHS1	O60500-1.1	Y109D	Pathogenic	0.998
NPHS1	O60500-1.1	Y109E	Pathogenic	0.998
NPHS1	O60500-1.1	Y109F	Pathogenic	0.998
NPHS1	O60500-1.1	Y109G	Pathogenic	0.998
NPHS1	O60500-1.1	Y109H	Pathogenic	0.998
NPHS1	O60500-1.1	Y109I	Pathogenic	0.994
NPHS1	O60500-1.1	Y109K	Pathogenic	0.998
NPHS1	O60500-1.1	Y109L	Pathogenic	0.993
NPHS1	O60500-1.1	Y109M	Pathogenic	0.986
NPHS1	O60500-1.1	Y109N	Pathogenic	0.998
NPHS1	O60500-1.1	Y109P	Pathogenic	0.985
NPHS1	O60500-1.1	Y109Q	Pathogenic	0.997
NPHS1	O60500-1.1	Y109R	Pathogenic	0.998
NPHS1	O60500-1.1	Y109S	Pathogenic	0.998
NPHS1	O60500-1.1	Y109T	Pathogenic	0.995
NPHS1	O60500-1.1	Y109V	Pathogenic	0.991
NPHS1	O60500-1.1	Y109W	Pathogenic	0.999
NPHS1	O60500-1.1	E110A	Pathogenic	0.987
NPHS1	O60500-1.1	E110C	Pathogenic	0.976
NPHS1	O60500-1.1	E110D	Pathogenic	0.977
NPHS1	O60500-1.1	E110F	Pathogenic	0.995
NPHS1	O60500-1.1	E110G	Pathogenic	0.981
NPHS1	O60500-1.1	E110H	Pathogenic	0.976
NPHS1	O60500-1.1	E110I	Pathogenic	0.994
NPHS1	O60500-1.1	E110K	Pathogenic	0.98
NPHS1	O60500-1.1	E110L	Pathogenic	0.993
NPHS1	O60500-1.1	E110M	Pathogenic	0.991
NPHS1	O60500-1.1	E110N	Pathogenic	0.937
NPHS1	O60500-1.1	E110P	Pathogenic	0.988
NPHS1	O60500-1.1	E110Q	Pathogenic	0.98
NPHS1	O60500-1.1	E110R	Pathogenic	0.978
NPHS1	O60500-1.1	E110S	Pathogenic	0.983
NPHS1	O60500-1.1	E110T	Pathogenic	0.974
NPHS1	O60500-1.1	E110V	Pathogenic	0.988
NPHS1	O60500-1.1	E110W	Pathogenic	0.999
NPHS1	O60500-1.1	E110Y	Pathogenic	0.991
NPHS1	O60500-1.1	C111A	Pathogenic	0.976
NPHS1	O60500-1.1	C111D	Pathogenic	0.978
NPHS1	O60500-1.1	C111E	Pathogenic	0.974
NPHS1	O60500-1.1	C111F	Pathogenic	0.979
NPHS1	O60500-1.1	C111G	Pathogenic	0.969
NPHS1	O60500-1.1	C111H	Pathogenic	0.957
NPHS1	O60500-1.1	C111I	Pathogenic	0.982
NPHS1	O60500-1.1	C111K	Pathogenic	0.994
NPHS1	O60500-1.1	C111L	Pathogenic	0.979
NPHS1	O60500-1.1	C111M	Pathogenic	0.958
NPHS1	O60500-1.1	C111N	Pathogenic	0.975
NPHS1	O60500-1.1	C111P	Pathogenic	0.826
NPHS1	O60500-1.1	C111Q	Pathogenic	0.971
NPHS1	O60500-1.1	C111R	Pathogenic	0.996
NPHS1	O60500-1.1	C111S	Pathogenic	0.976
NPHS1	O60500-1.1	C111T	Pathogenic	0.957
NPHS1	O60500-1.1	C111V	Pathogenic	0.935
NPHS1	O60500-1.1	C111W	Pathogenic	0.994
NPHS1	O60500-1.1	C111Y	Pathogenic	0.943
NPHS1	O60500-1.1	Q112A	Pathogenic	0.996
NPHS1	O60500-1.1	Q112C	Pathogenic	0.995
NPHS1	O60500-1.1	Q112D	Pathogenic	0.995
NPHS1	O60500-1.1	Q112E	Pathogenic	0.996
NPHS1	O60500-1.1	Q112F	Pathogenic	0.998
NPHS1	O60500-1.1	Q112G	Pathogenic	0.994
NPHS1	O60500-1.1	Q112H	Pathogenic	0.991
NPHS1	O60500-1.1	Q112I	Pathogenic	0.998
NPHS1	O60500-1.1	Q112K	Pathogenic	0.998
NPHS1	O60500-1.1	Q112L	Pathogenic	0.998
NPHS1	O60500-1.1	Q112M	Pathogenic	0.998
NPHS1	O60500-1.1	Q112N	Pathogenic	0.993
NPHS1	O60500-1.1	Q112P	Pathogenic	0.996
NPHS1	O60500-1.1	Q112R	Pathogenic	0.998
NPHS1	O60500-1.1	Q112S	Pathogenic	0.995
NPHS1	O60500-1.1	Q112T	Pathogenic	0.992
NPHS1	O60500-1.1	Q112V	Pathogenic	0.996
NPHS1	O60500-1.1	Q112W	Pathogenic	1.0
NPHS1	O60500-1.1	Q112Y	Pathogenic	0.998
NPHS1	O60500-1.1	V113A	Pathogenic	0.942
NPHS1	O60500-1.1	V113C	Pathogenic	0.718
NPHS1	O60500-1.1	V113D	Pathogenic	0.932
NPHS1	O60500-1.1	V113E	Pathogenic	0.93
NPHS1	O60500-1.1	V113F	Pathogenic	0.845
NPHS1	O60500-1.1	V113G	Pathogenic	0.924
NPHS1	O60500-1.1	V113H	Pathogenic	0.779
NPHS1	O60500-1.1	V113I	Pathogenic	0.955
NPHS1	O60500-1.1	V113K	Pathogenic	0.977
NPHS1	O60500-1.1	V113L	Pathogenic	0.891
NPHS1	O60500-1.1	V113M	Pathogenic	0.803
NPHS1	O60500-1.1	V113N	Pathogenic	0.905
NPHS1	O60500-1.1	V113P	Pathogenic	0.697
NPHS1	O60500-1.1	V113Q	Pathogenic	0.89
NPHS1	O60500-1.1	V113R	Pathogenic	0.975
NPHS1	O60500-1.1	V113S	Pathogenic	0.914
NPHS1	O60500-1.1	V113T	Pathogenic	0.905
NPHS1	O60500-1.1	V113W	Pathogenic	0.904
NPHS1	O60500-1.1	V113Y	Pathogenic	0.797
NPHS1	O60500-1.1	G114A	Pathogenic	0.724
NPHS1	O60500-1.1	G114C	Pathogenic	0.772
NPHS1	O60500-1.1	G114D	Pathogenic	0.86
NPHS1	O60500-1.1	G114E	Pathogenic	0.839
NPHS1	O60500-1.1	G114F	Pathogenic	0.973
NPHS1	O60500-1.1	G114H	Pathogenic	0.752
NPHS1	O60500-1.1	G114I	Pathogenic	0.95
NPHS1	O60500-1.1	G114K	Pathogenic	0.942
NPHS1	O60500-1.1	G114L	Pathogenic	0.942
NPHS1	O60500-1.1	G114M	Pathogenic	0.923
NPHS1	O60500-1.1	G114N	Pathogenic	0.89
NPHS1	O60500-1.1	G114P	Pathogenic	0.789
NPHS1	O60500-1.1	G114Q	Pathogenic	0.758
NPHS1	O60500-1.1	G114R	Pathogenic	0.958
NPHS1	O60500-1.1	G114S	Pathogenic	0.669
NPHS1	O60500-1.1	G114T	Pathogenic	0.669
NPHS1	O60500-1.1	G114V	Pathogenic	0.882
NPHS1	O60500-1.1	G114W	Pathogenic	0.995
NPHS1	O60500-1.1	G114Y	Pathogenic	0.923
NPHS1	O60500-1.1	R115A	Pathogenic	0.979
NPHS1	O60500-1.1	R115C	Pathogenic	0.974
NPHS1	O60500-1.1	R115D	Pathogenic	0.783
NPHS1	O60500-1.1	R115E	Pathogenic	0.865
NPHS1	O60500-1.1	R115F	Pathogenic	0.975
NPHS1	O60500-1.1	R115G	Pathogenic	0.969
NPHS1	O60500-1.1	R115H	Pathogenic	0.942
NPHS1	O60500-1.1	R115I	Pathogenic	0.981
NPHS1	O60500-1.1	R115K	Pathogenic	0.82
NPHS1	O60500-1.1	R115L	Pathogenic	0.985
NPHS1	O60500-1.1	R115M	Pathogenic	0.98
NPHS1	O60500-1.1	R115N	Pathogenic	0.902
NPHS1	O60500-1.1	R115P	Pathogenic	0.971
NPHS1	O60500-1.1	R115Q	Pathogenic	0.94
NPHS1	O60500-1.1	R115S	Pathogenic	0.961
NPHS1	O60500-1.1	R115T	Pathogenic	0.959
NPHS1	O60500-1.1	R115V	Pathogenic	0.971
NPHS1	O60500-1.1	R115W	Pathogenic	0.988
NPHS1	O60500-1.1	R115Y	Pathogenic	0.936
NPHS1	O60500-1.1	S116A	Pathogenic	0.836
NPHS1	O60500-1.1	S116C	Pathogenic	0.881
NPHS1	O60500-1.1	S116D	Pathogenic	0.89
NPHS1	O60500-1.1	S116E	Pathogenic	0.91
NPHS1	O60500-1.1	S116F	Pathogenic	0.981
NPHS1	O60500-1.1	S116G	Pathogenic	0.772
NPHS1	O60500-1.1	S116H	Pathogenic	0.816
NPHS1	O60500-1.1	S116I	Pathogenic	0.976
NPHS1	O60500-1.1	S116K	Pathogenic	0.969
NPHS1	O60500-1.1	S116L	Pathogenic	0.972
NPHS1	O60500-1.1	S116M	Pathogenic	0.963
NPHS1	O60500-1.1	S116N	Pathogenic	0.914
NPHS1	O60500-1.1	S116P	Pathogenic	0.845
NPHS1	O60500-1.1	S116Q	Pathogenic	0.86
NPHS1	O60500-1.1	S116R	Pathogenic	0.967
NPHS1	O60500-1.1	S116T	Pathogenic	0.868
NPHS1	O60500-1.1	S116V	Pathogenic	0.917
NPHS1	O60500-1.1	S116W	Pathogenic	0.993
NPHS1	O60500-1.1	S116Y	Pathogenic	0.946
NPHS1	O60500-1.1	E117A	Pathogenic	0.847
NPHS1	O60500-1.1	E117C	Pathogenic	0.744
NPHS1	O60500-1.1	E117D	Pathogenic	0.756
NPHS1	O60500-1.1	E117F	Pathogenic	0.939
NPHS1	O60500-1.1	E117G	Pathogenic	0.786
NPHS1	O60500-1.1	E117H	Pathogenic	0.744
NPHS1	O60500-1.1	E117I	Pathogenic	0.924
NPHS1	O60500-1.1	E117K	Pathogenic	0.777
NPHS1	O60500-1.1	E117L	Pathogenic	0.913
NPHS1	O60500-1.1	E117M	Pathogenic	0.886
NPHS1	O60500-1.1	E117N	Pathogenic	0.518
NPHS1	O60500-1.1	E117P	Pathogenic	0.856
NPHS1	O60500-1.1	E117Q	Pathogenic	0.777
NPHS1	O60500-1.1	E117R	Pathogenic	0.765
NPHS1	O60500-1.1	E117S	Pathogenic	0.811
NPHS1	O60500-1.1	E117T	Pathogenic	0.735
NPHS1	O60500-1.1	E117V	Pathogenic	0.854
NPHS1	O60500-1.1	E117W	Pathogenic	0.983
NPHS1	O60500-1.1	E117Y	Pathogenic	0.886
NPHS1	O60500-1.1	M118A	Neutral	0.077
NPHS1	O60500-1.1	M118C	Neutral	0.019
NPHS1	O60500-1.1	M118D	Neutral	0.096
NPHS1	O60500-1.1	M118E	Neutral	0.078
NPHS1	O60500-1.1	M118F	Neutral	0.024
NPHS1	O60500-1.1	M118G	Neutral	0.085
NPHS1	O60500-1.1	M118H	Neutral	0.021
NPHS1	O60500-1.1	M118I	Neutral	0.028
NPHS1	O60500-1.1	M118K	Neutral	0.163
NPHS1	O60500-1.1	M118L	Neutral	0.035
NPHS1	O60500-1.1	M118N	Neutral	0.098
NPHS1	O60500-1.1	M118P	Neutral	0.017
NPHS1	O60500-1.1	M118Q	Neutral	0.083
NPHS1	O60500-1.1	M118R	Neutral	0.213
NPHS1	O60500-1.1	M118S	Neutral	0.108
NPHS1	O60500-1.1	M118T	Neutral	0.047
NPHS1	O60500-1.1	M118V	Neutral	0.019
NPHS1	O60500-1.1	M118W	Neutral	0.059
NPHS1	O60500-1.1	M118Y	Neutral	0.012
NPHS1	O60500-1.1	G119A	Pathogenic	0.613
NPHS1	O60500-1.1	G119C	Pathogenic	0.671
NPHS1	O60500-1.1	G119D	Pathogenic	0.788
NPHS1	O60500-1.1	G119E	Pathogenic	0.758
NPHS1	O60500-1.1	G119F	Pathogenic	0.956
NPHS1	O60500-1.1	G119H	Pathogenic	0.646
NPHS1	O60500-1.1	G119I	Pathogenic	0.919
NPHS1	O60500-1.1	G119K	Pathogenic	0.907
NPHS1	O60500-1.1	G119L	Pathogenic	0.907
NPHS1	O60500-1.1	G119M	Pathogenic	0.879
NPHS1	O60500-1.1	G119N	Pathogenic	0.829
NPHS1	O60500-1.1	G119P	Pathogenic	0.693
NPHS1	O60500-1.1	G119Q	Pathogenic	0.654
NPHS1	O60500-1.1	G119R	Pathogenic	0.931
NPHS1	O60500-1.1	G119S	Pathogenic	0.549
NPHS1	O60500-1.1	G119T	Pathogenic	0.549
NPHS1	O60500-1.1	G119V	Pathogenic	0.819
NPHS1	O60500-1.1	G119W	Pathogenic	0.992
NPHS1	O60500-1.1	G119Y	Pathogenic	0.879
NPHS1	O60500-1.1	P120A	Neutral	0.12
NPHS1	O60500-1.1	P120C	Neutral	0.031
NPHS1	O60500-1.1	P120D	Neutral	0.288
NPHS1	O60500-1.1	P120E	Neutral	0.337
NPHS1	O60500-1.1	P120F	Neutral	0.156
NPHS1	O60500-1.1	P120G	Neutral	0.185
NPHS1	O60500-1.1	P120H	Neutral	0.118
NPHS1	O60500-1.1	P120I	Neutral	0.179
NPHS1	O60500-1.1	P120K	Pathogenic	0.613
NPHS1	O60500-1.1	P120L	Neutral	0.157
NPHS1	O60500-1.1	P120M	Neutral	0.122
NPHS1	O60500-1.1	P120N	Neutral	0.192
NPHS1	O60500-1.1	P120Q	Neutral	0.235
NPHS1	O60500-1.1	P120R	Pathogenic	0.597
NPHS1	O60500-1.1	P120S	Neutral	0.165
NPHS1	O60500-1.1	P120T	Neutral	0.084
NPHS1	O60500-1.1	P120V	Neutral	0.08
NPHS1	O60500-1.1	P120W	Neutral	0.416
NPHS1	O60500-1.1	P120Y	Neutral	0.085
NPHS1	O60500-1.1	E121A	Pathogenic	0.532
NPHS1	O60500-1.1	E121C	Neutral	0.374
NPHS1	O60500-1.1	E121D	Neutral	0.389
NPHS1	O60500-1.1	E121F	Pathogenic	0.76
NPHS1	O60500-1.1	E121G	Neutral	0.43
NPHS1	O60500-1.1	E121H	Neutral	0.374
NPHS1	O60500-1.1	E121I	Pathogenic	0.714
NPHS1	O60500-1.1	E121K	Neutral	0.417
NPHS1	O60500-1.1	E121L	Pathogenic	0.682
NPHS1	O60500-1.1	E121M	Pathogenic	0.614
NPHS1	O60500-1.1	E121N	Neutral	0.181
NPHS1	O60500-1.1	E121P	Pathogenic	0.549
NPHS1	O60500-1.1	E121Q	Neutral	0.417
NPHS1	O60500-1.1	E121R	Neutral	0.4
NPHS1	O60500-1.1	E121S	Neutral	0.468
NPHS1	O60500-1.1	E121T	Neutral	0.363
NPHS1	O60500-1.1	E121V	Pathogenic	0.546
NPHS1	O60500-1.1	E121W	Pathogenic	0.924
NPHS1	O60500-1.1	E121Y	Pathogenic	0.614
NPHS1	O60500-1.1	L122A	Pathogenic	0.777
NPHS1	O60500-1.1	L122C	Neutral	0.449
NPHS1	O60500-1.1	L122D	Pathogenic	0.748
NPHS1	O60500-1.1	L122E	Pathogenic	0.703
NPHS1	O60500-1.1	L122F	Neutral	0.201
NPHS1	O60500-1.1	L122G	Pathogenic	0.722
NPHS1	O60500-1.1	L122H	Neutral	0.379
NPHS1	O60500-1.1	L122I	Neutral	0.306
NPHS1	O60500-1.1	L122K	Pathogenic	0.845
NPHS1	O60500-1.1	L122M	Neutral	0.432
NPHS1	O60500-1.1	L122N	Pathogenic	0.753
NPHS1	O60500-1.1	L122P	Neutral	0.33
NPHS1	O60500-1.1	L122Q	Pathogenic	0.628
NPHS1	O60500-1.1	L122R	Pathogenic	0.883
NPHS1	O60500-1.1	L122S	Pathogenic	0.772
NPHS1	O60500-1.1	L122T	Pathogenic	0.67
NPHS1	O60500-1.1	L122V	Neutral	0.449
NPHS1	O60500-1.1	L122W	Neutral	0.303
NPHS1	O60500-1.1	L122Y	Neutral	0.339
NPHS1	O60500-1.1	V123A	Pathogenic	0.864
NPHS1	O60500-1.1	V123C	Neutral	0.499
NPHS1	O60500-1.1	V123D	Pathogenic	0.844
NPHS1	O60500-1.1	V123E	Pathogenic	0.839
NPHS1	O60500-1.1	V123F	Pathogenic	0.681
NPHS1	O60500-1.1	V123G	Pathogenic	0.826
NPHS1	O60500-1.1	V123H	Pathogenic	0.58
NPHS1	O60500-1.1	V123I	Pathogenic	0.893
NPHS1	O60500-1.1	V123K	Pathogenic	0.942
NPHS1	O60500-1.1	V123L	Pathogenic	0.763
NPHS1	O60500-1.1	V123M	Pathogenic	0.615
NPHS1	O60500-1.1	V123N	Pathogenic	0.789
NPHS1	O60500-1.1	V123P	Neutral	0.474
NPHS1	O60500-1.1	V123Q	Pathogenic	0.76
NPHS1	O60500-1.1	V123R	Pathogenic	0.938
NPHS1	O60500-1.1	V123S	Pathogenic	0.805
NPHS1	O60500-1.1	V123T	Pathogenic	0.788
NPHS1	O60500-1.1	V123W	Pathogenic	0.787
NPHS1	O60500-1.1	V123Y	Pathogenic	0.606
NPHS1	O60500-1.1	S124A	Pathogenic	0.972
NPHS1	O60500-1.1	S124C	Pathogenic	0.98
NPHS1	O60500-1.1	S124D	Pathogenic	0.982
NPHS1	O60500-1.1	S124E	Pathogenic	0.986
NPHS1	O60500-1.1	S124F	Pathogenic	0.997
NPHS1	O60500-1.1	S124G	Pathogenic	0.958
NPHS1	O60500-1.1	S124H	Pathogenic	0.968
NPHS1	O60500-1.1	S124I	Pathogenic	0.996
NPHS1	O60500-1.1	S124K	Pathogenic	0.995
NPHS1	O60500-1.1	S124L	Pathogenic	0.996
NPHS1	O60500-1.1	S124M	Pathogenic	0.994
NPHS1	O60500-1.1	S124N	Pathogenic	0.986
NPHS1	O60500-1.1	S124P	Pathogenic	0.974
NPHS1	O60500-1.1	S124Q	Pathogenic	0.977
NPHS1	O60500-1.1	S124R	Pathogenic	0.995
NPHS1	O60500-1.1	S124T	Pathogenic	0.978
NPHS1	O60500-1.1	S124V	Pathogenic	0.987
NPHS1	O60500-1.1	S124W	Pathogenic	0.999
NPHS1	O60500-1.1	S124Y	Pathogenic	0.992
NPHS1	O60500-1.1	P125A	Neutral	0.16
NPHS1	O60500-1.1	P125C	Neutral	0.042
NPHS1	O60500-1.1	P125D	Neutral	0.36
NPHS1	O60500-1.1	P125E	Neutral	0.414
NPHS1	O60500-1.1	P125F	Neutral	0.205
NPHS1	O60500-1.1	P125G	Neutral	0.24
NPHS1	O60500-1.1	P125H	Neutral	0.157
NPHS1	O60500-1.1	P125I	Neutral	0.233
NPHS1	O60500-1.1	P125K	Pathogenic	0.688
NPHS1	O60500-1.1	P125L	Neutral	0.206
NPHS1	O60500-1.1	P125M	Neutral	0.162
NPHS1	O60500-1.1	P125N	Neutral	0.248
NPHS1	O60500-1.1	P125Q	Neutral	0.3
NPHS1	O60500-1.1	P125R	Pathogenic	0.673
NPHS1	O60500-1.1	P125S	Neutral	0.216
NPHS1	O60500-1.1	P125T	Neutral	0.114
NPHS1	O60500-1.1	P125V	Neutral	0.108
NPHS1	O60500-1.1	P125W	Neutral	0.498
NPHS1	O60500-1.1	P125Y	Neutral	0.114
NPHS1	O60500-1.1	R126A	Pathogenic	0.617
NPHS1	O60500-1.1	R126C	Pathogenic	0.558
NPHS1	O60500-1.1	R126D	Neutral	0.11
NPHS1	O60500-1.1	R126E	Neutral	0.179
NPHS1	O60500-1.1	R126F	Pathogenic	0.568
NPHS1	O60500-1.1	R126G	Pathogenic	0.517
NPHS1	O60500-1.1	R126H	Neutral	0.357
NPHS1	O60500-1.1	R126I	Pathogenic	0.636
NPHS1	O60500-1.1	R126K	Neutral	0.135
NPHS1	O60500-1.1	R126L	Pathogenic	0.691
NPHS1	O60500-1.1	R126M	Pathogenic	0.624
NPHS1	O60500-1.1	R126N	Neutral	0.238
NPHS1	O60500-1.1	R126P	Pathogenic	0.536
NPHS1	O60500-1.1	R126Q	Neutral	0.35
NPHS1	O60500-1.1	R126S	Neutral	0.456
NPHS1	O60500-1.1	R126T	Neutral	0.447
NPHS1	O60500-1.1	R126V	Pathogenic	0.533
NPHS1	O60500-1.1	R126W	Pathogenic	0.733
NPHS1	O60500-1.1	R126Y	Neutral	0.332
NPHS1	O60500-1.1	V127A	Pathogenic	0.873
NPHS1	O60500-1.1	V127C	Pathogenic	0.519
NPHS1	O60500-1.1	V127D	Pathogenic	0.854
NPHS1	O60500-1.1	V127E	Pathogenic	0.85
NPHS1	O60500-1.1	V127F	Pathogenic	0.698
NPHS1	O60500-1.1	V127G	Pathogenic	0.837
NPHS1	O60500-1.1	V127H	Pathogenic	0.599
NPHS1	O60500-1.1	V127I	Pathogenic	0.9
NPHS1	O60500-1.1	V127K	Pathogenic	0.946
NPHS1	O60500-1.1	V127L	Pathogenic	0.777
NPHS1	O60500-1.1	V127M	Pathogenic	0.634
NPHS1	O60500-1.1	V127N	Pathogenic	0.802
NPHS1	O60500-1.1	V127P	Neutral	0.494
NPHS1	O60500-1.1	V127Q	Pathogenic	0.774
NPHS1	O60500-1.1	V127R	Pathogenic	0.943
NPHS1	O60500-1.1	V127S	Pathogenic	0.818
NPHS1	O60500-1.1	V127T	Pathogenic	0.801
NPHS1	O60500-1.1	V127W	Pathogenic	0.8
NPHS1	O60500-1.1	V127Y	Pathogenic	0.625
NPHS1	O60500-1.1	I128A	Pathogenic	0.713
NPHS1	O60500-1.1	I128C	Neutral	0.367
NPHS1	O60500-1.1	I128D	Pathogenic	0.759
NPHS1	O60500-1.1	I128E	Pathogenic	0.628
NPHS1	O60500-1.1	I128F	Neutral	0.121
NPHS1	O60500-1.1	I128G	Pathogenic	0.649
NPHS1	O60500-1.1	I128H	Neutral	0.303
NPHS1	O60500-1.1	I128K	Pathogenic	0.722
NPHS1	O60500-1.1	I128L	Neutral	0.212
NPHS1	O60500-1.1	I128M	Neutral	0.266
NPHS1	O60500-1.1	I128N	Pathogenic	0.685
NPHS1	O60500-1.1	I128P	Neutral	0.26
NPHS1	O60500-1.1	I128Q	Neutral	0.446
NPHS1	O60500-1.1	I128R	Pathogenic	0.783
NPHS1	O60500-1.1	I128S	Pathogenic	0.707
NPHS1	O60500-1.1	I128T	Pathogenic	0.591
NPHS1	O60500-1.1	I128V	Pathogenic	0.564
NPHS1	O60500-1.1	I128W	Neutral	0.133
NPHS1	O60500-1.1	I128Y	Neutral	0.267
NPHS1	O60500-1.1	L129A	Pathogenic	0.925
NPHS1	O60500-1.1	L129C	Pathogenic	0.741
NPHS1	O60500-1.1	L129D	Pathogenic	0.912
NPHS1	O60500-1.1	L129E	Pathogenic	0.893
NPHS1	O60500-1.1	L129F	Neutral	0.469
NPHS1	O60500-1.1	L129G	Pathogenic	0.902
NPHS1	O60500-1.1	L129H	Pathogenic	0.682
NPHS1	O60500-1.1	L129I	Pathogenic	0.608
NPHS1	O60500-1.1	L129K	Pathogenic	0.95
NPHS1	O60500-1.1	L129M	Pathogenic	0.728
NPHS1	O60500-1.1	L129N	Pathogenic	0.915
NPHS1	O60500-1.1	L129P	Pathogenic	0.635
NPHS1	O60500-1.1	L129Q	Pathogenic	0.856
NPHS1	O60500-1.1	L129R	Pathogenic	0.964
NPHS1	O60500-1.1	L129S	Pathogenic	0.923
NPHS1	O60500-1.1	L129T	Pathogenic	0.877
NPHS1	O60500-1.1	L129V	Pathogenic	0.742
NPHS1	O60500-1.1	L129W	Pathogenic	0.605
NPHS1	O60500-1.1	L129Y	Pathogenic	0.643
NPHS1	O60500-1.1	S130A	Pathogenic	0.527
NPHS1	O60500-1.1	S130C	Pathogenic	0.617
NPHS1	O60500-1.1	S130D	Pathogenic	0.639
NPHS1	O60500-1.1	S130E	Pathogenic	0.69
NPHS1	O60500-1.1	S130F	Pathogenic	0.92
NPHS1	O60500-1.1	S130G	Neutral	0.425
NPHS1	O60500-1.1	S130H	Neutral	0.492
NPHS1	O60500-1.1	S130I	Pathogenic	0.9
NPHS1	O60500-1.1	S130K	Pathogenic	0.874
NPHS1	O60500-1.1	S130L	Pathogenic	0.886
NPHS1	O60500-1.1	S130M	Pathogenic	0.852
NPHS1	O60500-1.1	S130N	Pathogenic	0.698
NPHS1	O60500-1.1	S130P	Pathogenic	0.545
NPHS1	O60500-1.1	S130Q	Pathogenic	0.573
NPHS1	O60500-1.1	S130R	Pathogenic	0.866
NPHS1	O60500-1.1	S130T	Pathogenic	0.59
NPHS1	O60500-1.1	S130V	Pathogenic	0.706
NPHS1	O60500-1.1	S130W	Pathogenic	0.967
NPHS1	O60500-1.1	S130Y	Pathogenic	0.793
NPHS1	O60500-1.1	I131A	Pathogenic	0.981
NPHS1	O60500-1.1	I131C	Pathogenic	0.925
NPHS1	O60500-1.1	I131D	Pathogenic	0.985
NPHS1	O60500-1.1	I131E	Pathogenic	0.973
NPHS1	O60500-1.1	I131F	Pathogenic	0.744
NPHS1	O60500-1.1	I131G	Pathogenic	0.975
NPHS1	O60500-1.1	I131H	Pathogenic	0.902
NPHS1	O60500-1.1	I131K	Pathogenic	0.982
NPHS1	O60500-1.1	I131L	Pathogenic	0.85
NPHS1	O60500-1.1	I131M	Pathogenic	0.884
NPHS1	O60500-1.1	I131N	Pathogenic	0.979
NPHS1	O60500-1.1	I131P	Pathogenic	0.881
NPHS1	O60500-1.1	I131Q	Pathogenic	0.944
NPHS1	O60500-1.1	I131R	Pathogenic	0.987
NPHS1	O60500-1.1	I131S	Pathogenic	0.981
NPHS1	O60500-1.1	I131T	Pathogenic	0.968
NPHS1	O60500-1.1	I131V	Pathogenic	0.965
NPHS1	O60500-1.1	I131W	Pathogenic	0.764
NPHS1	O60500-1.1	I131Y	Pathogenic	0.885
NPHS1	O60500-1.1	L132A	Pathogenic	0.981
NPHS1	O60500-1.1	L132C	Pathogenic	0.923
NPHS1	O60500-1.1	L132D	Pathogenic	0.978
NPHS1	O60500-1.1	L132E	Pathogenic	0.972
NPHS1	O60500-1.1	L132F	Pathogenic	0.788
NPHS1	O60500-1.1	L132G	Pathogenic	0.975
NPHS1	O60500-1.1	L132H	Pathogenic	0.9
NPHS1	O60500-1.1	L132I	Pathogenic	0.867
NPHS1	O60500-1.1	L132K	Pathogenic	0.988
NPHS1	O60500-1.1	L132M	Pathogenic	0.918
NPHS1	O60500-1.1	L132N	Pathogenic	0.978
NPHS1	O60500-1.1	L132P	Pathogenic	0.879
NPHS1	O60500-1.1	L132Q	Pathogenic	0.961
NPHS1	O60500-1.1	L132R	Pathogenic	0.991
NPHS1	O60500-1.1	L132S	Pathogenic	0.98
NPHS1	O60500-1.1	L132T	Pathogenic	0.968
NPHS1	O60500-1.1	L132V	Pathogenic	0.923
NPHS1	O60500-1.1	L132W	Pathogenic	0.865
NPHS1	O60500-1.1	L132Y	Pathogenic	0.883
NPHS1	O60500-1.1	V133A	Pathogenic	0.875
NPHS1	O60500-1.1	V133C	Pathogenic	0.524
NPHS1	O60500-1.1	V133D	Pathogenic	0.856
NPHS1	O60500-1.1	V133E	Pathogenic	0.852
NPHS1	O60500-1.1	V133F	Pathogenic	0.702
NPHS1	O60500-1.1	V133G	Pathogenic	0.84
NPHS1	O60500-1.1	V133H	Pathogenic	0.603
NPHS1	O60500-1.1	V133I	Pathogenic	0.902
NPHS1	O60500-1.1	V133K	Pathogenic	0.947
NPHS1	O60500-1.1	V133L	Pathogenic	0.78
NPHS1	O60500-1.1	V133M	Pathogenic	0.638
NPHS1	O60500-1.1	V133N	Pathogenic	0.805
NPHS1	O60500-1.1	V133P	Neutral	0.498
NPHS1	O60500-1.1	V133Q	Pathogenic	0.777
NPHS1	O60500-1.1	V133R	Pathogenic	0.944
NPHS1	O60500-1.1	V133S	Pathogenic	0.82
NPHS1	O60500-1.1	V133T	Pathogenic	0.804
NPHS1	O60500-1.1	V133W	Pathogenic	0.803
NPHS1	O60500-1.1	V133Y	Pathogenic	0.629
NPHS1	O60500-1.1	P134A	Pathogenic	0.814
NPHS1	O60500-1.1	P134C	Pathogenic	0.502
NPHS1	O60500-1.1	P134D	Pathogenic	0.928
NPHS1	O60500-1.1	P134E	Pathogenic	0.942
NPHS1	O60500-1.1	P134F	Pathogenic	0.855
NPHS1	O60500-1.1	P134G	Pathogenic	0.879
NPHS1	O60500-1.1	P134H	Pathogenic	0.811
NPHS1	O60500-1.1	P134I	Pathogenic	0.874
NPHS1	O60500-1.1	P134K	Pathogenic	0.981
NPHS1	O60500-1.1	P134L	Pathogenic	0.857
NPHS1	O60500-1.1	P134M	Pathogenic	0.816
NPHS1	O60500-1.1	P134N	Pathogenic	0.884
NPHS1	O60500-1.1	P134Q	Pathogenic	0.908
NPHS1	O60500-1.1	P134R	Pathogenic	0.979
NPHS1	O60500-1.1	P134S	Pathogenic	0.864
NPHS1	O60500-1.1	P134T	Pathogenic	0.746
NPHS1	O60500-1.1	P134V	Pathogenic	0.735
NPHS1	O60500-1.1	P134W	Pathogenic	0.958
NPHS1	O60500-1.1	P134Y	Pathogenic	0.748
NPHS1	O60500-1.1	P135A	Pathogenic	0.868
NPHS1	O60500-1.1	P135C	Pathogenic	0.604
NPHS1	O60500-1.1	P135D	Pathogenic	0.951
NPHS1	O60500-1.1	P135E	Pathogenic	0.961
NPHS1	O60500-1.1	P135F	Pathogenic	0.899
NPHS1	O60500-1.1	P135G	Pathogenic	0.916
NPHS1	O60500-1.1	P135H	Pathogenic	0.866
NPHS1	O60500-1.1	P135I	Pathogenic	0.913
NPHS1	O60500-1.1	P135K	Pathogenic	0.987
NPHS1	O60500-1.1	P135L	Pathogenic	0.9
NPHS1	O60500-1.1	P135M	Pathogenic	0.87
NPHS1	O60500-1.1	P135N	Pathogenic	0.92
NPHS1	O60500-1.1	P135Q	Pathogenic	0.937
NPHS1	O60500-1.1	P135R	Pathogenic	0.986
NPHS1	O60500-1.1	P135S	Pathogenic	0.905
NPHS1	O60500-1.1	P135T	Pathogenic	0.816
NPHS1	O60500-1.1	P135V	Pathogenic	0.807
NPHS1	O60500-1.1	P135W	Pathogenic	0.972
NPHS1	O60500-1.1	P135Y	Pathogenic	0.817
NPHS1	O60500-1.1	K136A	Pathogenic	0.978
NPHS1	O60500-1.1	K136C	Pathogenic	0.972
NPHS1	O60500-1.1	K136D	Pathogenic	0.833
NPHS1	O60500-1.1	K136E	Pathogenic	0.898
NPHS1	O60500-1.1	K136F	Pathogenic	0.973
NPHS1	O60500-1.1	K136G	Pathogenic	0.967
NPHS1	O60500-1.1	K136H	Pathogenic	0.91
NPHS1	O60500-1.1	K136I	Pathogenic	0.979
NPHS1	O60500-1.1	K136L	Pathogenic	0.984
NPHS1	O60500-1.1	K136M	Pathogenic	0.978
NPHS1	O60500-1.1	K136N	Pathogenic	0.895
NPHS1	O60500-1.1	K136P	Pathogenic	0.979
NPHS1	O60500-1.1	K136Q	Pathogenic	0.936
NPHS1	O60500-1.1	K136R	Pathogenic	0.854
NPHS1	O60500-1.1	K136S	Pathogenic	0.971
NPHS1	O60500-1.1	K136T	Pathogenic	0.956
NPHS1	O60500-1.1	K136V	Pathogenic	0.979
NPHS1	O60500-1.1	K136W	Pathogenic	0.993
NPHS1	O60500-1.1	K136Y	Pathogenic	0.947
NPHS1	O60500-1.1	L137A	Neutral	0.003
NPHS1	O60500-1.1	L137C	Neutral	0.001
NPHS1	O60500-1.1	L137D	Neutral	0.002
NPHS1	O60500-1.1	L137E	Neutral	0.002
NPHS1	O60500-1.1	L137F	Neutral	0.0
NPHS1	O60500-1.1	L137G	Neutral	0.002
NPHS1	O60500-1.1	L137H	Neutral	0.0
NPHS1	O60500-1.1	L137I	Neutral	0.0
NPHS1	O60500-1.1	L137K	Neutral	0.004
NPHS1	O60500-1.1	L137M	Neutral	0.001
NPHS1	O60500-1.1	L137N	Neutral	0.002
NPHS1	O60500-1.1	L137P	Neutral	0.0
NPHS1	O60500-1.1	L137Q	Neutral	0.001
NPHS1	O60500-1.1	L137R	Neutral	0.006
NPHS1	O60500-1.1	L137S	Neutral	0.003
NPHS1	O60500-1.1	L137T	Neutral	0.002
NPHS1	O60500-1.1	L137V	Neutral	0.001
NPHS1	O60500-1.1	L137W	Neutral	0.0
NPHS1	O60500-1.1	L137Y	Neutral	0.0
NPHS1	O60500-1.1	L138A	Pathogenic	0.773
NPHS1	O60500-1.1	L138C	Neutral	0.444
NPHS1	O60500-1.1	L138D	Pathogenic	0.744
NPHS1	O60500-1.1	L138E	Pathogenic	0.699
NPHS1	O60500-1.1	L138F	Neutral	0.198
NPHS1	O60500-1.1	L138G	Pathogenic	0.718
NPHS1	O60500-1.1	L138H	Neutral	0.374
NPHS1	O60500-1.1	L138I	Neutral	0.301
NPHS1	O60500-1.1	L138K	Pathogenic	0.842
NPHS1	O60500-1.1	L138M	Neutral	0.427
NPHS1	O60500-1.1	L138N	Pathogenic	0.749
NPHS1	O60500-1.1	L138P	Neutral	0.326
NPHS1	O60500-1.1	L138Q	Pathogenic	0.623
NPHS1	O60500-1.1	L138R	Pathogenic	0.881
NPHS1	O60500-1.1	L138S	Pathogenic	0.768
NPHS1	O60500-1.1	L138T	Pathogenic	0.666
NPHS1	O60500-1.1	L138V	Neutral	0.444
NPHS1	O60500-1.1	L138W	Neutral	0.299
NPHS1	O60500-1.1	L138Y	Neutral	0.334
NPHS1	O60500-1.1	L139A	Neutral	0.001
NPHS1	O60500-1.1	L139C	Neutral	0.0
NPHS1	O60500-1.1	L139D	Neutral	0.001
NPHS1	O60500-1.1	L139E	Neutral	0.001
NPHS1	O60500-1.1	L139F	Neutral	0.0
NPHS1	O60500-1.1	L139G	Neutral	0.001
NPHS1	O60500-1.1	L139H	Neutral	0.0
NPHS1	O60500-1.1	L139I	Neutral	0.0
NPHS1	O60500-1.1	L139K	Neutral	0.002
NPHS1	O60500-1.1	L139M	Neutral	0.0
NPHS1	O60500-1.1	L139N	Neutral	0.001
NPHS1	O60500-1.1	L139P	Neutral	0.0
NPHS1	O60500-1.1	L139Q	Neutral	0.001
NPHS1	O60500-1.1	L139R	Neutral	0.003
NPHS1	O60500-1.1	L139S	Neutral	0.001
NPHS1	O60500-1.1	L139T	Neutral	0.001
NPHS1	O60500-1.1	L139V	Neutral	0.0
NPHS1	O60500-1.1	L139W	Neutral	0.0
NPHS1	O60500-1.1	L139Y	Neutral	0.0
NPHS1	O60500-1.1	L140A	Neutral	0.387
NPHS1	O60500-1.1	L140C	Neutral	0.129
NPHS1	O60500-1.1	L140D	Neutral	0.349
NPHS1	O60500-1.1	L140E	Neutral	0.3
NPHS1	O60500-1.1	L140F	Neutral	0.044
NPHS1	O60500-1.1	L140G	Neutral	0.32
NPHS1	O60500-1.1	L140H	Neutral	0.099
NPHS1	O60500-1.1	L140I	Neutral	0.074
NPHS1	O60500-1.1	L140K	Neutral	0.496
NPHS1	O60500-1.1	L140M	Neutral	0.121
NPHS1	O60500-1.1	L140N	Neutral	0.356
NPHS1	O60500-1.1	L140P	Neutral	0.082
NPHS1	O60500-1.1	L140Q	Neutral	0.234
NPHS1	O60500-1.1	L140R	Pathogenic	0.578
NPHS1	O60500-1.1	L140S	Neutral	0.38
NPHS1	O60500-1.1	L140T	Neutral	0.269
NPHS1	O60500-1.1	L140V	Neutral	0.129
NPHS1	O60500-1.1	L140W	Neutral	0.073
NPHS1	O60500-1.1	L140Y	Neutral	0.085
NPHS1	O60500-1.1	T141A	Neutral	0.176
NPHS1	O60500-1.1	T141C	Neutral	0.2
NPHS1	O60500-1.1	T141D	Neutral	0.257
NPHS1	O60500-1.1	T141E	Neutral	0.284
NPHS1	O60500-1.1	T141F	Pathogenic	0.56
NPHS1	O60500-1.1	T141G	Neutral	0.17
NPHS1	O60500-1.1	T141H	Neutral	0.095
NPHS1	O60500-1.1	T141I	Pathogenic	0.599
NPHS1	O60500-1.1	T141K	Pathogenic	0.553
NPHS1	O60500-1.1	T141L	Pathogenic	0.562
NPHS1	O60500-1.1	T141M	Neutral	0.389
NPHS1	O60500-1.1	T141N	Neutral	0.292
NPHS1	O60500-1.1	T141P	Neutral	0.133
NPHS1	O60500-1.1	T141Q	Neutral	0.193
NPHS1	O60500-1.1	T141R	Pathogenic	0.632
NPHS1	O60500-1.1	T141S	Neutral	0.284
NPHS1	O60500-1.1	T141V	Neutral	0.373
NPHS1	O60500-1.1	T141W	Pathogenic	0.83
NPHS1	O60500-1.1	T141Y	Neutral	0.299
NPHS1	O60500-1.1	P142A	Neutral	0.197
NPHS1	O60500-1.1	P142C	Neutral	0.054
NPHS1	O60500-1.1	P142D	Neutral	0.42
NPHS1	O60500-1.1	P142E	Neutral	0.477
NPHS1	O60500-1.1	P142F	Neutral	0.249
NPHS1	O60500-1.1	P142G	Neutral	0.29
NPHS1	O60500-1.1	P142H	Neutral	0.194
NPHS1	O60500-1.1	P142I	Neutral	0.281
NPHS1	O60500-1.1	P142K	Pathogenic	0.74
NPHS1	O60500-1.1	P142L	Neutral	0.251
NPHS1	O60500-1.1	P142M	Neutral	0.199
NPHS1	O60500-1.1	P142N	Neutral	0.299
NPHS1	O60500-1.1	P142Q	Neutral	0.355
NPHS1	O60500-1.1	P142R	Pathogenic	0.726
NPHS1	O60500-1.1	P142S	Neutral	0.262
NPHS1	O60500-1.1	P142T	Neutral	0.142
NPHS1	O60500-1.1	P142V	Neutral	0.134
NPHS1	O60500-1.1	P142W	Pathogenic	0.561
NPHS1	O60500-1.1	P142Y	Neutral	0.143
NPHS1	O60500-1.1	E143A	Pathogenic	0.932
NPHS1	O60500-1.1	E143C	Pathogenic	0.878
NPHS1	O60500-1.1	E143D	Pathogenic	0.885
NPHS1	O60500-1.1	E143F	Pathogenic	0.975
NPHS1	O60500-1.1	E143G	Pathogenic	0.901
NPHS1	O60500-1.1	E143H	Pathogenic	0.879
NPHS1	O60500-1.1	E143I	Pathogenic	0.968
NPHS1	O60500-1.1	E143K	Pathogenic	0.896
NPHS1	O60500-1.1	E143L	Pathogenic	0.963
NPHS1	O60500-1.1	E143M	Pathogenic	0.951
NPHS1	O60500-1.1	E143N	Pathogenic	0.728
NPHS1	O60500-1.1	E143P	Pathogenic	0.936
NPHS1	O60500-1.1	E143Q	Pathogenic	0.897
NPHS1	O60500-1.1	E143R	Pathogenic	0.89
NPHS1	O60500-1.1	E143S	Pathogenic	0.914
NPHS1	O60500-1.1	E143T	Pathogenic	0.873
NPHS1	O60500-1.1	E143V	Pathogenic	0.936
NPHS1	O60500-1.1	E143W	Pathogenic	0.993
NPHS1	O60500-1.1	E143Y	Pathogenic	0.951
NPHS1	O60500-1.1	A144C	Neutral	0.428
NPHS1	O60500-1.1	A144D	Neutral	0.408
NPHS1	O60500-1.1	A144E	Pathogenic	0.564
NPHS1	O60500-1.1	A144F	Pathogenic	0.78
NPHS1	O60500-1.1	A144G	Neutral	0.302
NPHS1	O60500-1.1	A144H	Neutral	0.254
NPHS1	O60500-1.1	A144I	Pathogenic	0.807
NPHS1	O60500-1.1	A144K	Pathogenic	0.801
NPHS1	O60500-1.1	A144L	Pathogenic	0.782
NPHS1	O60500-1.1	A144M	Pathogenic	0.641
NPHS1	O60500-1.1	A144N	Neutral	0.376
NPHS1	O60500-1.1	A144P	Neutral	0.271
NPHS1	O60500-1.1	A144Q	Neutral	0.438
NPHS1	O60500-1.1	A144R	Pathogenic	0.849
NPHS1	O60500-1.1	A144S	Neutral	0.334
NPHS1	O60500-1.1	A144T	Neutral	0.259
NPHS1	O60500-1.1	A144V	Pathogenic	0.624
NPHS1	O60500-1.1	A144W	Pathogenic	0.902
NPHS1	O60500-1.1	A144Y	Pathogenic	0.544
NPHS1	O60500-1.1	G145A	Neutral	0.172
NPHS1	O60500-1.1	G145C	Neutral	0.212
NPHS1	O60500-1.1	G145D	Neutral	0.329
NPHS1	O60500-1.1	G145E	Neutral	0.292
NPHS1	O60500-1.1	G145F	Pathogenic	0.739
NPHS1	O60500-1.1	G145H	Neutral	0.194
NPHS1	O60500-1.1	G145I	Pathogenic	0.6
NPHS1	O60500-1.1	G145K	Pathogenic	0.563
NPHS1	O60500-1.1	G145L	Pathogenic	0.563
NPHS1	O60500-1.1	G145M	Neutral	0.489
NPHS1	O60500-1.1	G145N	Neutral	0.39
NPHS1	O60500-1.1	G145P	Neutral	0.229
NPHS1	O60500-1.1	G145Q	Neutral	0.2
NPHS1	O60500-1.1	G145R	Pathogenic	0.642
NPHS1	O60500-1.1	G145S	Neutral	0.138
NPHS1	O60500-1.1	G145T	Neutral	0.138
NPHS1	O60500-1.1	G145V	Neutral	0.374
NPHS1	O60500-1.1	G145W	Pathogenic	0.942
NPHS1	O60500-1.1	G145Y	Neutral	0.488
NPHS1	O60500-1.1	T146A	Neutral	0.042
NPHS1	O60500-1.1	T146C	Neutral	0.049
NPHS1	O60500-1.1	T146D	Neutral	0.067
NPHS1	O60500-1.1	T146E	Neutral	0.075
NPHS1	O60500-1.1	T146F	Neutral	0.207
NPHS1	O60500-1.1	T146G	Neutral	0.04
NPHS1	O60500-1.1	T146H	Neutral	0.021
NPHS1	O60500-1.1	T146I	Neutral	0.235
NPHS1	O60500-1.1	T146K	Neutral	0.203
NPHS1	O60500-1.1	T146L	Neutral	0.209
NPHS1	O60500-1.1	T146M	Neutral	0.116
NPHS1	O60500-1.1	T146N	Neutral	0.078
NPHS1	O60500-1.1	T146P	Neutral	0.031
NPHS1	O60500-1.1	T146Q	Neutral	0.047
NPHS1	O60500-1.1	T146R	Neutral	0.261
NPHS1	O60500-1.1	T146S	Neutral	0.075
NPHS1	O60500-1.1	T146V	Neutral	0.109
NPHS1	O60500-1.1	T146W	Pathogenic	0.502
NPHS1	O60500-1.1	T146Y	Neutral	0.081
NPHS1	O60500-1.1	M147A	Neutral	0.296
NPHS1	O60500-1.1	M147C	Neutral	0.09
NPHS1	O60500-1.1	M147D	Neutral	0.348
NPHS1	O60500-1.1	M147E	Neutral	0.3
NPHS1	O60500-1.1	M147F	Neutral	0.109
NPHS1	O60500-1.1	M147G	Neutral	0.319
NPHS1	O60500-1.1	M147H	Neutral	0.099
NPHS1	O60500-1.1	M147I	Neutral	0.126
NPHS1	O60500-1.1	M147K	Neutral	0.495
NPHS1	O60500-1.1	M147L	Neutral	0.156
NPHS1	O60500-1.1	M147N	Neutral	0.355
NPHS1	O60500-1.1	M147P	Neutral	0.082
NPHS1	O60500-1.1	M147Q	Neutral	0.312
NPHS1	O60500-1.1	M147R	Pathogenic	0.577
NPHS1	O60500-1.1	M147S	Neutral	0.379
NPHS1	O60500-1.1	M147T	Neutral	0.197
NPHS1	O60500-1.1	M147V	Neutral	0.09
NPHS1	O60500-1.1	M147W	Neutral	0.241
NPHS1	O60500-1.1	M147Y	Neutral	0.058
NPHS1	O60500-1.1	V148A	Pathogenic	0.938
NPHS1	O60500-1.1	V148C	Pathogenic	0.704
NPHS1	O60500-1.1	V148D	Pathogenic	0.928
NPHS1	O60500-1.1	V148E	Pathogenic	0.926
NPHS1	O60500-1.1	V148F	Pathogenic	0.836
NPHS1	O60500-1.1	V148G	Pathogenic	0.919
NPHS1	O60500-1.1	V148H	Pathogenic	0.767
NPHS1	O60500-1.1	V148I	Pathogenic	0.952
NPHS1	O60500-1.1	V148K	Pathogenic	0.975
NPHS1	O60500-1.1	V148L	Pathogenic	0.885
NPHS1	O60500-1.1	V148M	Pathogenic	0.792
NPHS1	O60500-1.1	V148N	Pathogenic	0.899
NPHS1	O60500-1.1	V148P	Pathogenic	0.682
NPHS1	O60500-1.1	V148Q	Pathogenic	0.883
NPHS1	O60500-1.1	V148R	Pathogenic	0.973
NPHS1	O60500-1.1	V148S	Pathogenic	0.908
NPHS1	O60500-1.1	V148T	Pathogenic	0.898
NPHS1	O60500-1.1	V148W	Pathogenic	0.898
NPHS1	O60500-1.1	V148Y	Pathogenic	0.786
NPHS1	O60500-1.1	T149A	Pathogenic	0.745
NPHS1	O60500-1.1	T149C	Pathogenic	0.773
NPHS1	O60500-1.1	T149D	Pathogenic	0.826
NPHS1	O60500-1.1	T149E	Pathogenic	0.844
NPHS1	O60500-1.1	T149F	Pathogenic	0.945
NPHS1	O60500-1.1	T149G	Pathogenic	0.736
NPHS1	O60500-1.1	T149H	Pathogenic	0.588
NPHS1	O60500-1.1	T149I	Pathogenic	0.953
NPHS1	O60500-1.1	T149K	Pathogenic	0.944
NPHS1	O60500-1.1	T149L	Pathogenic	0.946
NPHS1	O60500-1.1	T149M	Pathogenic	0.897
NPHS1	O60500-1.1	T149N	Pathogenic	0.849
NPHS1	O60500-1.1	T149P	Pathogenic	0.677
NPHS1	O60500-1.1	T149Q	Pathogenic	0.766
NPHS1	O60500-1.1	T149R	Pathogenic	0.959
NPHS1	O60500-1.1	T149S	Pathogenic	0.844
NPHS1	O60500-1.1	T149V	Pathogenic	0.89
NPHS1	O60500-1.1	T149W	Pathogenic	0.985
NPHS1	O60500-1.1	T149Y	Pathogenic	0.853
NPHS1	O60500-1.1	W150A	Pathogenic	1.0
NPHS1	O60500-1.1	W150C	Pathogenic	1.0
NPHS1	O60500-1.1	W150D	Pathogenic	1.0
NPHS1	O60500-1.1	W150E	Pathogenic	1.0
NPHS1	O60500-1.1	W150F	Pathogenic	0.999
NPHS1	O60500-1.1	W150G	Pathogenic	1.0
NPHS1	O60500-1.1	W150H	Pathogenic	1.0
NPHS1	O60500-1.1	W150I	Pathogenic	0.997
NPHS1	O60500-1.1	W150K	Pathogenic	1.0
NPHS1	O60500-1.1	W150L	Pathogenic	0.998
NPHS1	O60500-1.1	W150M	Pathogenic	0.999
NPHS1	O60500-1.1	W150N	Pathogenic	1.0
NPHS1	O60500-1.1	W150P	Pathogenic	1.0
NPHS1	O60500-1.1	W150Q	Pathogenic	1.0
NPHS1	O60500-1.1	W150R	Pathogenic	1.0
NPHS1	O60500-1.1	W150S	Pathogenic	1.0
NPHS1	O60500-1.1	W150T	Pathogenic	1.0
NPHS1	O60500-1.1	W150V	Pathogenic	0.999
NPHS1	O60500-1.1	W150Y	Pathogenic	1.0
NPHS1	O60500-1.1	V151A	Pathogenic	0.989
NPHS1	O60500-1.1	V151C	Pathogenic	0.936
NPHS1	O60500-1.1	V151D	Pathogenic	0.987
NPHS1	O60500-1.1	V151E	Pathogenic	0.987
NPHS1	O60500-1.1	V151F	Pathogenic	0.969
NPHS1	O60500-1.1	V151G	Pathogenic	0.986
NPHS1	O60500-1.1	V151H	Pathogenic	0.953
NPHS1	O60500-1.1	V151I	Pathogenic	0.992
NPHS1	O60500-1.1	V151K	Pathogenic	0.996
NPHS1	O60500-1.1	V151L	Pathogenic	0.979
NPHS1	O60500-1.1	V151M	Pathogenic	0.959
NPHS1	O60500-1.1	V151N	Pathogenic	0.982
NPHS1	O60500-1.1	V151P	Pathogenic	0.929
NPHS1	O60500-1.1	V151Q	Pathogenic	0.979
NPHS1	O60500-1.1	V151R	Pathogenic	0.996
NPHS1	O60500-1.1	V151S	Pathogenic	0.984
NPHS1	O60500-1.1	V151T	Pathogenic	0.982
NPHS1	O60500-1.1	V151W	Pathogenic	0.982
NPHS1	O60500-1.1	V151Y	Pathogenic	0.957
NPHS1	O60500-1.1	A152C	Pathogenic	0.944
NPHS1	O60500-1.1	A152D	Pathogenic	0.939
NPHS1	O60500-1.1	A152E	Pathogenic	0.967
NPHS1	O60500-1.1	A152F	Pathogenic	0.988
NPHS1	O60500-1.1	A152G	Pathogenic	0.906
NPHS1	O60500-1.1	A152H	Pathogenic	0.884
NPHS1	O60500-1.1	A152I	Pathogenic	0.989
NPHS1	O60500-1.1	A152K	Pathogenic	0.989
NPHS1	O60500-1.1	A152L	Pathogenic	0.988
NPHS1	O60500-1.1	A152M	Pathogenic	0.976
NPHS1	O60500-1.1	A152N	Pathogenic	0.931
NPHS1	O60500-1.1	A152P	Pathogenic	0.893
NPHS1	O60500-1.1	A152Q	Pathogenic	0.946
NPHS1	O60500-1.1	A152R	Pathogenic	0.992
NPHS1	O60500-1.1	A152S	Pathogenic	0.918
NPHS1	O60500-1.1	A152T	Pathogenic	0.886
NPHS1	O60500-1.1	A152V	Pathogenic	0.974
NPHS1	O60500-1.1	A152W	Pathogenic	0.995
NPHS1	O60500-1.1	A152Y	Pathogenic	0.964
NPHS1	O60500-1.1	G153A	Pathogenic	0.965
NPHS1	O60500-1.1	G153C	Pathogenic	0.972
NPHS1	O60500-1.1	G153D	Pathogenic	0.985
NPHS1	O60500-1.1	G153E	Pathogenic	0.982
NPHS1	O60500-1.1	G153F	Pathogenic	0.997
NPHS1	O60500-1.1	G153H	Pathogenic	0.969
NPHS1	O60500-1.1	G153I	Pathogenic	0.995
NPHS1	O60500-1.1	G153K	Pathogenic	0.994
NPHS1	O60500-1.1	G153L	Pathogenic	0.994
NPHS1	O60500-1.1	G153M	Pathogenic	0.992
NPHS1	O60500-1.1	G153N	Pathogenic	0.988
NPHS1	O60500-1.1	G153P	Pathogenic	0.975
NPHS1	O60500-1.1	G153Q	Pathogenic	0.97
NPHS1	O60500-1.1	G153R	Pathogenic	0.996
NPHS1	O60500-1.1	G153S	Pathogenic	0.955
NPHS1	O60500-1.1	G153T	Pathogenic	0.955
NPHS1	O60500-1.1	G153V	Pathogenic	0.987
NPHS1	O60500-1.1	G153W	Pathogenic	1.0
NPHS1	O60500-1.1	G153Y	Pathogenic	0.992
NPHS1	O60500-1.1	Q154A	Neutral	0.304
NPHS1	O60500-1.1	Q154C	Neutral	0.254
NPHS1	O60500-1.1	Q154D	Neutral	0.276
NPHS1	O60500-1.1	Q154E	Neutral	0.313
NPHS1	O60500-1.1	Q154F	Neutral	0.49
NPHS1	O60500-1.1	Q154G	Neutral	0.225
NPHS1	O60500-1.1	Q154H	Neutral	0.153
NPHS1	O60500-1.1	Q154I	Neutral	0.431
NPHS1	O60500-1.1	Q154K	Neutral	0.429
NPHS1	O60500-1.1	Q154L	Neutral	0.492
NPHS1	O60500-1.1	Q154M	Pathogenic	0.517
NPHS1	O60500-1.1	Q154N	Neutral	0.208
NPHS1	O60500-1.1	Q154P	Neutral	0.318
NPHS1	O60500-1.1	Q154R	Pathogenic	0.511
NPHS1	O60500-1.1	Q154S	Neutral	0.252
NPHS1	O60500-1.1	Q154T	Neutral	0.179
NPHS1	O60500-1.1	Q154V	Neutral	0.315
NPHS1	O60500-1.1	Q154W	Pathogenic	0.847
NPHS1	O60500-1.1	Q154Y	Neutral	0.418
NPHS1	O60500-1.1	E155A	Pathogenic	0.931
NPHS1	O60500-1.1	E155C	Pathogenic	0.877
NPHS1	O60500-1.1	E155D	Pathogenic	0.884
NPHS1	O60500-1.1	E155F	Pathogenic	0.974
NPHS1	O60500-1.1	E155G	Pathogenic	0.9
NPHS1	O60500-1.1	E155H	Pathogenic	0.877
NPHS1	O60500-1.1	E155I	Pathogenic	0.968
NPHS1	O60500-1.1	E155K	Pathogenic	0.895
NPHS1	O60500-1.1	E155L	Pathogenic	0.962
NPHS1	O60500-1.1	E155M	Pathogenic	0.95
NPHS1	O60500-1.1	E155N	Pathogenic	0.725
NPHS1	O60500-1.1	E155P	Pathogenic	0.936
NPHS1	O60500-1.1	E155Q	Pathogenic	0.895
NPHS1	O60500-1.1	E155R	Pathogenic	0.889
NPHS1	O60500-1.1	E155S	Pathogenic	0.913
NPHS1	O60500-1.1	E155T	Pathogenic	0.872
NPHS1	O60500-1.1	E155V	Pathogenic	0.935
NPHS1	O60500-1.1	E155W	Pathogenic	0.993
NPHS1	O60500-1.1	E155Y	Pathogenic	0.95
NPHS1	O60500-1.1	Y156A	Pathogenic	0.998
NPHS1	O60500-1.1	Y156C	Pathogenic	0.994
NPHS1	O60500-1.1	Y156D	Pathogenic	0.999
NPHS1	O60500-1.1	Y156E	Pathogenic	0.999
NPHS1	O60500-1.1	Y156F	Pathogenic	0.999
NPHS1	O60500-1.1	Y156G	Pathogenic	0.999
NPHS1	O60500-1.1	Y156H	Pathogenic	0.999
NPHS1	O60500-1.1	Y156I	Pathogenic	0.997
NPHS1	O60500-1.1	Y156K	Pathogenic	0.999
NPHS1	O60500-1.1	Y156L	Pathogenic	0.996
NPHS1	O60500-1.1	Y156M	Pathogenic	0.993
NPHS1	O60500-1.1	Y156N	Pathogenic	0.999
NPHS1	O60500-1.1	Y156P	Pathogenic	0.992
NPHS1	O60500-1.1	Y156Q	Pathogenic	0.999
NPHS1	O60500-1.1	Y156R	Pathogenic	0.999
NPHS1	O60500-1.1	Y156S	Pathogenic	0.999
NPHS1	O60500-1.1	Y156T	Pathogenic	0.997
NPHS1	O60500-1.1	Y156V	Pathogenic	0.995
NPHS1	O60500-1.1	Y156W	Pathogenic	1.0
NPHS1	O60500-1.1	V157A	Neutral	0.033
NPHS1	O60500-1.1	V157C	Neutral	0.005
NPHS1	O60500-1.1	V157D	Neutral	0.028
NPHS1	O60500-1.1	V157E	Neutral	0.027
NPHS1	O60500-1.1	V157F	Neutral	0.011
NPHS1	O60500-1.1	V157G	Neutral	0.025
NPHS1	O60500-1.1	V157H	Neutral	0.007
NPHS1	O60500-1.1	V157I	Neutral	0.042
NPHS1	O60500-1.1	V157K	Neutral	0.08
NPHS1	O60500-1.1	V157L	Neutral	0.017
NPHS1	O60500-1.1	V157M	Neutral	0.008
NPHS1	O60500-1.1	V157N	Neutral	0.019
NPHS1	O60500-1.1	V157P	Neutral	0.005
NPHS1	O60500-1.1	V157Q	Neutral	0.017
NPHS1	O60500-1.1	V157R	Neutral	0.075
NPHS1	O60500-1.1	V157S	Neutral	0.022
NPHS1	O60500-1.1	V157T	Neutral	0.019
NPHS1	O60500-1.1	V157W	Neutral	0.019
NPHS1	O60500-1.1	V157Y	Neutral	0.008
NPHS1	O60500-1.1	V158A	Pathogenic	0.946
NPHS1	O60500-1.1	V158C	Pathogenic	0.734
NPHS1	O60500-1.1	V158D	Pathogenic	0.937
NPHS1	O60500-1.1	V158E	Pathogenic	0.935
NPHS1	O60500-1.1	V158F	Pathogenic	0.855
NPHS1	O60500-1.1	V158G	Pathogenic	0.929
NPHS1	O60500-1.1	V158H	Pathogenic	0.792
NPHS1	O60500-1.1	V158I	Pathogenic	0.958
NPHS1	O60500-1.1	V158K	Pathogenic	0.978
NPHS1	O60500-1.1	V158L	Pathogenic	0.899
NPHS1	O60500-1.1	V158M	Pathogenic	0.815
NPHS1	O60500-1.1	V158N	Pathogenic	0.912
NPHS1	O60500-1.1	V158P	Pathogenic	0.713
NPHS1	O60500-1.1	V158Q	Pathogenic	0.897
NPHS1	O60500-1.1	V158R	Pathogenic	0.977
NPHS1	O60500-1.1	V158S	Pathogenic	0.92
NPHS1	O60500-1.1	V158T	Pathogenic	0.911
NPHS1	O60500-1.1	V158W	Pathogenic	0.911
NPHS1	O60500-1.1	V158Y	Pathogenic	0.81
NPHS1	O60500-1.1	N159A	Neutral	0.005
NPHS1	O60500-1.1	N159C	Neutral	0.006
NPHS1	O60500-1.1	N159D	Neutral	0.003
NPHS1	O60500-1.1	N159E	Neutral	0.002
NPHS1	O60500-1.1	N159F	Neutral	0.039
NPHS1	O60500-1.1	N159G	Neutral	0.012
NPHS1	O60500-1.1	N159H	Neutral	0.011
NPHS1	O60500-1.1	N159I	Neutral	0.031
NPHS1	O60500-1.1	N159K	Neutral	0.007
NPHS1	O60500-1.1	N159L	Neutral	0.027
NPHS1	O60500-1.1	N159M	Neutral	0.02
NPHS1	O60500-1.1	N159P	Neutral	0.006
NPHS1	O60500-1.1	N159Q	Neutral	0.004
NPHS1	O60500-1.1	N159R	Neutral	0.01
NPHS1	O60500-1.1	N159S	Neutral	0.009
NPHS1	O60500-1.1	N159T	Neutral	0.006
NPHS1	O60500-1.1	N159V	Neutral	0.009
NPHS1	O60500-1.1	N159W	Neutral	0.096
NPHS1	O60500-1.1	N159Y	Neutral	0.02
NPHS1	O60500-1.1	C160A	Pathogenic	0.955
NPHS1	O60500-1.1	C160D	Pathogenic	0.958
NPHS1	O60500-1.1	C160E	Pathogenic	0.951
NPHS1	O60500-1.1	C160F	Pathogenic	0.96
NPHS1	O60500-1.1	C160G	Pathogenic	0.941
NPHS1	O60500-1.1	C160H	Pathogenic	0.919
NPHS1	O60500-1.1	C160I	Pathogenic	0.965
NPHS1	O60500-1.1	C160K	Pathogenic	0.989
NPHS1	O60500-1.1	C160L	Pathogenic	0.96
NPHS1	O60500-1.1	C160M	Pathogenic	0.923
NPHS1	O60500-1.1	C160N	Pathogenic	0.953
NPHS1	O60500-1.1	C160P	Pathogenic	0.711
NPHS1	O60500-1.1	C160Q	Pathogenic	0.946
NPHS1	O60500-1.1	C160R	Pathogenic	0.992
NPHS1	O60500-1.1	C160S	Pathogenic	0.954
NPHS1	O60500-1.1	C160T	Pathogenic	0.921
NPHS1	O60500-1.1	C160V	Pathogenic	0.882
NPHS1	O60500-1.1	C160W	Pathogenic	0.989
NPHS1	O60500-1.1	C160Y	Pathogenic	0.895
NPHS1	O60500-1.1	V161A	Neutral	0.149
NPHS1	O60500-1.1	V161C	Neutral	0.027
NPHS1	O60500-1.1	V161D	Neutral	0.13
NPHS1	O60500-1.1	V161E	Neutral	0.126
NPHS1	O60500-1.1	V161F	Neutral	0.056
NPHS1	O60500-1.1	V161G	Neutral	0.116
NPHS1	O60500-1.1	V161H	Neutral	0.037
NPHS1	O60500-1.1	V161I	Neutral	0.187
NPHS1	O60500-1.1	V161K	Neutral	0.31
NPHS1	O60500-1.1	V161L	Neutral	0.081
NPHS1	O60500-1.1	V161M	Neutral	0.042
NPHS1	O60500-1.1	V161N	Neutral	0.093
NPHS1	O60500-1.1	V161P	Neutral	0.024
NPHS1	O60500-1.1	V161Q	Neutral	0.08
NPHS1	O60500-1.1	V161R	Neutral	0.295
NPHS1	O60500-1.1	V161S	Neutral	0.102
NPHS1	O60500-1.1	V161T	Neutral	0.093
NPHS1	O60500-1.1	V161W	Neutral	0.093
NPHS1	O60500-1.1	V161Y	Neutral	0.041
NPHS1	O60500-1.1	S162A	Neutral	0.184
NPHS1	O60500-1.1	S162C	Neutral	0.246
NPHS1	O60500-1.1	S162D	Neutral	0.263
NPHS1	O60500-1.1	S162E	Neutral	0.31
NPHS1	O60500-1.1	S162F	Pathogenic	0.698
NPHS1	O60500-1.1	S162G	Neutral	0.13
NPHS1	O60500-1.1	S162H	Neutral	0.164
NPHS1	O60500-1.1	S162I	Pathogenic	0.645
NPHS1	O60500-1.1	S162K	Pathogenic	0.584
NPHS1	O60500-1.1	S162L	Pathogenic	0.61
NPHS1	O60500-1.1	S162M	Pathogenic	0.537
NPHS1	O60500-1.1	S162N	Neutral	0.318
NPHS1	O60500-1.1	S162P	Neutral	0.195
NPHS1	O60500-1.1	S162Q	Neutral	0.213
NPHS1	O60500-1.1	S162R	Pathogenic	0.566
NPHS1	O60500-1.1	S162T	Neutral	0.225
NPHS1	O60500-1.1	S162V	Neutral	0.327
NPHS1	O60500-1.1	S162W	Pathogenic	0.856
NPHS1	O60500-1.1	S162Y	Neutral	0.437
NPHS1	O60500-1.1	G163A	Neutral	0.125
NPHS1	O60500-1.1	G163C	Neutral	0.156
NPHS1	O60500-1.1	G163D	Neutral	0.252
NPHS1	O60500-1.1	G163E	Neutral	0.221
NPHS1	O60500-1.1	G163F	Pathogenic	0.661
NPHS1	O60500-1.1	G163H	Neutral	0.142
NPHS1	O60500-1.1	G163I	Pathogenic	0.507
NPHS1	O60500-1.1	G163K	Neutral	0.47
NPHS1	O60500-1.1	G163L	Neutral	0.469
NPHS1	O60500-1.1	G163M	Neutral	0.396
NPHS1	O60500-1.1	G163N	Neutral	0.305
NPHS1	O60500-1.1	G163P	Neutral	0.17
NPHS1	O60500-1.1	G163Q	Neutral	0.146
NPHS1	O60500-1.1	G163R	Pathogenic	0.552
NPHS1	O60500-1.1	G163S	Neutral	0.099
NPHS1	O60500-1.1	G163T	Neutral	0.099
NPHS1	O60500-1.1	G163V	Neutral	0.291
NPHS1	O60500-1.1	G163W	Pathogenic	0.918
NPHS1	O60500-1.1	G163Y	Neutral	0.396
NPHS1	O60500-1.1	D164A	Pathogenic	0.99
NPHS1	O60500-1.1	D164C	Pathogenic	0.992
NPHS1	O60500-1.1	D164E	Pathogenic	0.991
NPHS1	O60500-1.1	D164F	Pathogenic	0.999
NPHS1	O60500-1.1	D164G	Pathogenic	0.993
NPHS1	O60500-1.1	D164H	Pathogenic	0.992
NPHS1	O60500-1.1	D164I	Pathogenic	0.999
NPHS1	O60500-1.1	D164K	Pathogenic	0.985
NPHS1	O60500-1.1	D164L	Pathogenic	0.998
NPHS1	O60500-1.1	D164M	Pathogenic	0.997
NPHS1	O60500-1.1	D164N	Pathogenic	0.982
NPHS1	O60500-1.1	D164P	Pathogenic	0.994
NPHS1	O60500-1.1	D164Q	Pathogenic	0.99
NPHS1	O60500-1.1	D164R	Pathogenic	0.984
NPHS1	O60500-1.1	D164S	Pathogenic	0.991
NPHS1	O60500-1.1	D164T	Pathogenic	0.988
NPHS1	O60500-1.1	D164V	Pathogenic	0.995
NPHS1	O60500-1.1	D164W	Pathogenic	1.0
NPHS1	O60500-1.1	D164Y	Pathogenic	0.997
NPHS1	O60500-1.1	A165C	Pathogenic	0.952
NPHS1	O60500-1.1	A165D	Pathogenic	0.948
NPHS1	O60500-1.1	A165E	Pathogenic	0.971
NPHS1	O60500-1.1	A165F	Pathogenic	0.989
NPHS1	O60500-1.1	A165G	Pathogenic	0.919
NPHS1	O60500-1.1	A165H	Pathogenic	0.9
NPHS1	O60500-1.1	A165I	Pathogenic	0.991
NPHS1	O60500-1.1	A165K	Pathogenic	0.991
NPHS1	O60500-1.1	A165L	Pathogenic	0.99
NPHS1	O60500-1.1	A165M	Pathogenic	0.979
NPHS1	O60500-1.1	A165N	Pathogenic	0.941
NPHS1	O60500-1.1	A165P	Pathogenic	0.907
NPHS1	O60500-1.1	A165Q	Pathogenic	0.954
NPHS1	O60500-1.1	A165R	Pathogenic	0.993
NPHS1	O60500-1.1	A165S	Pathogenic	0.93
NPHS1	O60500-1.1	A165T	Pathogenic	0.902
NPHS1	O60500-1.1	A165V	Pathogenic	0.978
NPHS1	O60500-1.1	A165W	Pathogenic	0.996
NPHS1	O60500-1.1	A165Y	Pathogenic	0.969
NPHS1	O60500-1.1	K166A	Pathogenic	0.998
NPHS1	O60500-1.1	K166C	Pathogenic	0.997
NPHS1	O60500-1.1	K166D	Pathogenic	0.979
NPHS1	O60500-1.1	K166E	Pathogenic	0.988
NPHS1	O60500-1.1	K166F	Pathogenic	0.997
NPHS1	O60500-1.1	K166G	Pathogenic	0.996
NPHS1	O60500-1.1	K166H	Pathogenic	0.989
NPHS1	O60500-1.1	K166I	Pathogenic	0.998
NPHS1	O60500-1.1	K166L	Pathogenic	0.998
NPHS1	O60500-1.1	K166M	Pathogenic	0.998
NPHS1	O60500-1.1	K166N	Pathogenic	0.987
NPHS1	O60500-1.1	K166P	Pathogenic	0.998
NPHS1	O60500-1.1	K166Q	Pathogenic	0.993
NPHS1	O60500-1.1	K166R	Pathogenic	0.982
NPHS1	O60500-1.1	K166S	Pathogenic	0.997
NPHS1	O60500-1.1	K166T	Pathogenic	0.995
NPHS1	O60500-1.1	K166V	Pathogenic	0.998
NPHS1	O60500-1.1	K166W	Pathogenic	0.999
NPHS1	O60500-1.1	K166Y	Pathogenic	0.994
NPHS1	O60500-1.1	P167A	Pathogenic	0.951
NPHS1	O60500-1.1	P167C	Pathogenic	0.816
NPHS1	O60500-1.1	P167D	Pathogenic	0.983
NPHS1	O60500-1.1	P167E	Pathogenic	0.986
NPHS1	O60500-1.1	P167F	Pathogenic	0.963
NPHS1	O60500-1.1	P167G	Pathogenic	0.97
NPHS1	O60500-1.1	P167H	Pathogenic	0.95
NPHS1	O60500-1.1	P167I	Pathogenic	0.968
NPHS1	O60500-1.1	P167K	Pathogenic	0.996
NPHS1	O60500-1.1	P167L	Pathogenic	0.963
NPHS1	O60500-1.1	P167M	Pathogenic	0.951
NPHS1	O60500-1.1	P167N	Pathogenic	0.971
NPHS1	O60500-1.1	P167Q	Pathogenic	0.977
NPHS1	O60500-1.1	P167R	Pathogenic	0.995
NPHS1	O60500-1.1	P167S	Pathogenic	0.965
NPHS1	O60500-1.1	P167T	Pathogenic	0.928
NPHS1	O60500-1.1	P167V	Pathogenic	0.924
NPHS1	O60500-1.1	P167W	Pathogenic	0.99
NPHS1	O60500-1.1	P167Y	Pathogenic	0.929
NPHS1	O60500-1.1	A168C	Pathogenic	0.65
NPHS1	O60500-1.1	A168D	Pathogenic	0.631
NPHS1	O60500-1.1	A168E	Pathogenic	0.763
NPHS1	O60500-1.1	A168F	Pathogenic	0.898
NPHS1	O60500-1.1	A168G	Pathogenic	0.519
NPHS1	O60500-1.1	A168H	Neutral	0.459
NPHS1	O60500-1.1	A168I	Pathogenic	0.912
NPHS1	O60500-1.1	A168K	Pathogenic	0.909
NPHS1	O60500-1.1	A168L	Pathogenic	0.899
NPHS1	O60500-1.1	A168M	Pathogenic	0.816
NPHS1	O60500-1.1	A168N	Pathogenic	0.6
NPHS1	O60500-1.1	A168P	Neutral	0.48
NPHS1	O60500-1.1	A168Q	Pathogenic	0.66
NPHS1	O60500-1.1	A168R	Pathogenic	0.933
NPHS1	O60500-1.1	A168S	Pathogenic	0.555
NPHS1	O60500-1.1	A168T	Neutral	0.465
NPHS1	O60500-1.1	A168V	Pathogenic	0.805
NPHS1	O60500-1.1	A168W	Pathogenic	0.958
NPHS1	O60500-1.1	A168Y	Pathogenic	0.748
NPHS1	O60500-1.1	P169A	Neutral	0.23
NPHS1	O60500-1.1	P169C	Neutral	0.064
NPHS1	O60500-1.1	P169D	Neutral	0.469
NPHS1	O60500-1.1	P169E	Pathogenic	0.526
NPHS1	O60500-1.1	P169F	Neutral	0.288
NPHS1	O60500-1.1	P169G	Neutral	0.332
NPHS1	O60500-1.1	P169H	Neutral	0.226
NPHS1	O60500-1.1	P169I	Neutral	0.322
NPHS1	O60500-1.1	P169K	Pathogenic	0.776
NPHS1	O60500-1.1	P169L	Neutral	0.29
NPHS1	O60500-1.1	P169M	Neutral	0.232
NPHS1	O60500-1.1	P169N	Neutral	0.341
NPHS1	O60500-1.1	P169Q	Neutral	0.401
NPHS1	O60500-1.1	P169R	Pathogenic	0.763
NPHS1	O60500-1.1	P169S	Neutral	0.302
NPHS1	O60500-1.1	P169T	Neutral	0.167
NPHS1	O60500-1.1	P169V	Neutral	0.159
NPHS1	O60500-1.1	P169W	Pathogenic	0.609
NPHS1	O60500-1.1	P169Y	Neutral	0.168
NPHS1	O60500-1.1	D170A	Pathogenic	0.586
NPHS1	O60500-1.1	D170C	Pathogenic	0.623
NPHS1	O60500-1.1	D170E	Pathogenic	0.598
NPHS1	O60500-1.1	D170F	Pathogenic	0.932
NPHS1	O60500-1.1	D170G	Pathogenic	0.677
NPHS1	O60500-1.1	D170H	Pathogenic	0.636
NPHS1	O60500-1.1	D170I	Pathogenic	0.916
NPHS1	O60500-1.1	D170K	Neutral	0.486
NPHS1	O60500-1.1	D170L	Pathogenic	0.862
NPHS1	O60500-1.1	D170M	Pathogenic	0.823
NPHS1	O60500-1.1	D170N	Neutral	0.437
NPHS1	O60500-1.1	D170P	Pathogenic	0.693
NPHS1	O60500-1.1	D170Q	Pathogenic	0.584
NPHS1	O60500-1.1	D170R	Neutral	0.468
NPHS1	O60500-1.1	D170S	Pathogenic	0.621
NPHS1	O60500-1.1	D170T	Pathogenic	0.538
NPHS1	O60500-1.1	D170V	Pathogenic	0.744
NPHS1	O60500-1.1	D170W	Pathogenic	0.973
NPHS1	O60500-1.1	D170Y	Pathogenic	0.823
NPHS1	O60500-1.1	I171A	Pathogenic	0.996
NPHS1	O60500-1.1	I171C	Pathogenic	0.982
NPHS1	O60500-1.1	I171D	Pathogenic	0.997
NPHS1	O60500-1.1	I171E	Pathogenic	0.994
NPHS1	O60500-1.1	I171F	Pathogenic	0.929
NPHS1	O60500-1.1	I171G	Pathogenic	0.994
NPHS1	O60500-1.1	I171H	Pathogenic	0.976
NPHS1	O60500-1.1	I171K	Pathogenic	0.996
NPHS1	O60500-1.1	I171L	Pathogenic	0.962
NPHS1	O60500-1.1	I171M	Pathogenic	0.972
NPHS1	O60500-1.1	I171N	Pathogenic	0.995
NPHS1	O60500-1.1	I171P	Pathogenic	0.971
NPHS1	O60500-1.1	I171Q	Pathogenic	0.987
NPHS1	O60500-1.1	I171R	Pathogenic	0.997
NPHS1	O60500-1.1	I171S	Pathogenic	0.996
NPHS1	O60500-1.1	I171T	Pathogenic	0.993
NPHS1	O60500-1.1	I171V	Pathogenic	0.992
NPHS1	O60500-1.1	I171W	Pathogenic	0.936
NPHS1	O60500-1.1	I171Y	Pathogenic	0.972
NPHS1	O60500-1.1	T172A	Neutral	0.145
NPHS1	O60500-1.1	T172C	Neutral	0.165
NPHS1	O60500-1.1	T172D	Neutral	0.215
NPHS1	O60500-1.1	T172E	Neutral	0.239
NPHS1	O60500-1.1	T172F	Pathogenic	0.501
NPHS1	O60500-1.1	T172G	Neutral	0.139
NPHS1	O60500-1.1	T172H	Neutral	0.076
NPHS1	O60500-1.1	T172I	Pathogenic	0.541
NPHS1	O60500-1.1	T172K	Neutral	0.495
NPHS1	O60500-1.1	T172L	Pathogenic	0.503
NPHS1	O60500-1.1	T172M	Neutral	0.335
NPHS1	O60500-1.1	T172N	Neutral	0.246
NPHS1	O60500-1.1	T172P	Neutral	0.108
NPHS1	O60500-1.1	T172Q	Neutral	0.159
NPHS1	O60500-1.1	T172R	Pathogenic	0.576
NPHS1	O60500-1.1	T172S	Neutral	0.239
NPHS1	O60500-1.1	T172V	Neutral	0.32
NPHS1	O60500-1.1	T172W	Pathogenic	0.795
NPHS1	O60500-1.1	T172Y	Neutral	0.252
NPHS1	O60500-1.1	I173A	Pathogenic	0.724
NPHS1	O60500-1.1	I173C	Neutral	0.38
NPHS1	O60500-1.1	I173D	Pathogenic	0.769
NPHS1	O60500-1.1	I173E	Pathogenic	0.641
NPHS1	O60500-1.1	I173F	Neutral	0.127
NPHS1	O60500-1.1	I173G	Pathogenic	0.662
NPHS1	O60500-1.1	I173H	Neutral	0.314
NPHS1	O60500-1.1	I173K	Pathogenic	0.733
NPHS1	O60500-1.1	I173L	Neutral	0.221
NPHS1	O60500-1.1	I173M	Neutral	0.277
NPHS1	O60500-1.1	I173N	Pathogenic	0.697
NPHS1	O60500-1.1	I173P	Neutral	0.271
NPHS1	O60500-1.1	I173Q	Neutral	0.46
NPHS1	O60500-1.1	I173R	Pathogenic	0.792
NPHS1	O60500-1.1	I173S	Pathogenic	0.718
NPHS1	O60500-1.1	I173T	Pathogenic	0.605
NPHS1	O60500-1.1	I173V	Pathogenic	0.577
NPHS1	O60500-1.1	I173W	Neutral	0.139
NPHS1	O60500-1.1	I173Y	Neutral	0.278
NPHS1	O60500-1.1	L174A	Neutral	0.021
NPHS1	O60500-1.1	L174C	Neutral	0.005
NPHS1	O60500-1.1	L174D	Neutral	0.018
NPHS1	O60500-1.1	L174E	Neutral	0.015
NPHS1	O60500-1.1	L174F	Neutral	0.002
NPHS1	O60500-1.1	L174G	Neutral	0.016
NPHS1	O60500-1.1	L174H	Neutral	0.004
NPHS1	O60500-1.1	L174I	Neutral	0.003
NPHS1	O60500-1.1	L174K	Neutral	0.033
NPHS1	O60500-1.1	L174M	Neutral	0.005
NPHS1	O60500-1.1	L174N	Neutral	0.019
NPHS1	O60500-1.1	L174P	Neutral	0.003
NPHS1	O60500-1.1	L174Q	Neutral	0.011
NPHS1	O60500-1.1	L174R	Neutral	0.045
NPHS1	O60500-1.1	L174S	Neutral	0.021
NPHS1	O60500-1.1	L174T	Neutral	0.013
NPHS1	O60500-1.1	L174V	Neutral	0.005
NPHS1	O60500-1.1	L174W	Neutral	0.003
NPHS1	O60500-1.1	L174Y	Neutral	0.003
NPHS1	O60500-1.1	L175A	Neutral	0.037
NPHS1	O60500-1.1	L175C	Neutral	0.009
NPHS1	O60500-1.1	L175D	Neutral	0.032
NPHS1	O60500-1.1	L175E	Neutral	0.025
NPHS1	O60500-1.1	L175F	Neutral	0.003
NPHS1	O60500-1.1	L175G	Neutral	0.028
NPHS1	O60500-1.1	L175H	Neutral	0.007
NPHS1	O60500-1.1	L175I	Neutral	0.005
NPHS1	O60500-1.1	L175K	Neutral	0.056
NPHS1	O60500-1.1	L175M	Neutral	0.008
NPHS1	O60500-1.1	L175N	Neutral	0.032
NPHS1	O60500-1.1	L175P	Neutral	0.005
NPHS1	O60500-1.1	L175Q	Neutral	0.018
NPHS1	O60500-1.1	L175R	Neutral	0.077
NPHS1	O60500-1.1	L175S	Neutral	0.036
NPHS1	O60500-1.1	L175T	Neutral	0.022
NPHS1	O60500-1.1	L175V	Neutral	0.009
NPHS1	O60500-1.1	L175W	Neutral	0.005
NPHS1	O60500-1.1	L175Y	Neutral	0.006
NPHS1	O60500-1.1	S176A	Neutral	0.215
NPHS1	O60500-1.1	S176C	Neutral	0.283
NPHS1	O60500-1.1	S176D	Neutral	0.302
NPHS1	O60500-1.1	S176E	Neutral	0.353
NPHS1	O60500-1.1	S176F	Pathogenic	0.737
NPHS1	O60500-1.1	S176G	Neutral	0.154
NPHS1	O60500-1.1	S176H	Neutral	0.192
NPHS1	O60500-1.1	S176I	Pathogenic	0.688
NPHS1	O60500-1.1	S176K	Pathogenic	0.63
NPHS1	O60500-1.1	S176L	Pathogenic	0.655
NPHS1	O60500-1.1	S176M	Pathogenic	0.584
NPHS1	O60500-1.1	S176N	Neutral	0.362
NPHS1	O60500-1.1	S176P	Neutral	0.227
NPHS1	O60500-1.1	S176Q	Neutral	0.248
NPHS1	O60500-1.1	S176R	Pathogenic	0.613
NPHS1	O60500-1.1	S176T	Neutral	0.261
NPHS1	O60500-1.1	S176V	Neutral	0.371
NPHS1	O60500-1.1	S176W	Pathogenic	0.879
NPHS1	O60500-1.1	S176Y	Neutral	0.485
NPHS1	O60500-1.1	G177A	Pathogenic	0.763
NPHS1	O60500-1.1	G177C	Pathogenic	0.806
NPHS1	O60500-1.1	G177D	Pathogenic	0.883
NPHS1	O60500-1.1	G177E	Pathogenic	0.865
NPHS1	O60500-1.1	G177F	Pathogenic	0.978
NPHS1	O60500-1.1	G177H	Pathogenic	0.788
NPHS1	O60500-1.1	G177I	Pathogenic	0.959
NPHS1	O60500-1.1	G177K	Pathogenic	0.952
NPHS1	O60500-1.1	G177L	Pathogenic	0.952
NPHS1	O60500-1.1	G177M	Pathogenic	0.937
NPHS1	O60500-1.1	G177N	Pathogenic	0.908
NPHS1	O60500-1.1	G177P	Pathogenic	0.821
NPHS1	O60500-1.1	G177Q	Pathogenic	0.794
NPHS1	O60500-1.1	G177R	Pathogenic	0.965
NPHS1	O60500-1.1	G177S	Pathogenic	0.713
NPHS1	O60500-1.1	G177T	Pathogenic	0.713
NPHS1	O60500-1.1	G177V	Pathogenic	0.902
NPHS1	O60500-1.1	G177W	Pathogenic	0.996
NPHS1	O60500-1.1	G177Y	Pathogenic	0.936
NPHS1	O60500-1.1	Q178A	Neutral	0.066
NPHS1	O60500-1.1	Q178C	Neutral	0.052
NPHS1	O60500-1.1	Q178D	Neutral	0.058
NPHS1	O60500-1.1	Q178E	Neutral	0.068
NPHS1	O60500-1.1	Q178F	Neutral	0.134
NPHS1	O60500-1.1	Q178G	Neutral	0.045
NPHS1	O60500-1.1	Q178H	Neutral	0.028
NPHS1	O60500-1.1	Q178I	Neutral	0.109
NPHS1	O60500-1.1	Q178K	Neutral	0.108
NPHS1	O60500-1.1	Q178L	Neutral	0.135
NPHS1	O60500-1.1	Q178M	Neutral	0.148
NPHS1	O60500-1.1	Q178N	Neutral	0.041
NPHS1	O60500-1.1	Q178P	Neutral	0.07
NPHS1	O60500-1.1	Q178R	Neutral	0.144
NPHS1	O60500-1.1	Q178S	Neutral	0.052
NPHS1	O60500-1.1	Q178T	Neutral	0.034
NPHS1	O60500-1.1	Q178V	Neutral	0.069
NPHS1	O60500-1.1	Q178W	Neutral	0.471
NPHS1	O60500-1.1	Q178Y	Neutral	0.104
NPHS1	O60500-1.1	T179A	Neutral	0.019
NPHS1	O60500-1.1	T179C	Neutral	0.022
NPHS1	O60500-1.1	T179D	Neutral	0.031
NPHS1	O60500-1.1	T179E	Neutral	0.035
NPHS1	O60500-1.1	T179F	Neutral	0.104
NPHS1	O60500-1.1	T179G	Neutral	0.018
NPHS1	O60500-1.1	T179H	Neutral	0.01
NPHS1	O60500-1.1	T179I	Neutral	0.12
NPHS1	O60500-1.1	T179K	Neutral	0.102
NPHS1	O60500-1.1	T179L	Neutral	0.105
NPHS1	O60500-1.1	T179M	Neutral	0.055
NPHS1	O60500-1.1	T179N	Neutral	0.036
NPHS1	O60500-1.1	T179P	Neutral	0.014
NPHS1	O60500-1.1	T179Q	Neutral	0.022
NPHS1	O60500-1.1	T179R	Neutral	0.136
NPHS1	O60500-1.1	T179S	Neutral	0.035
NPHS1	O60500-1.1	T179V	Neutral	0.052
NPHS1	O60500-1.1	T179W	Neutral	0.31
NPHS1	O60500-1.1	T179Y	Neutral	0.038
NPHS1	O60500-1.1	I180A	Pathogenic	0.749
NPHS1	O60500-1.1	I180C	Neutral	0.411
NPHS1	O60500-1.1	I180D	Pathogenic	0.791
NPHS1	O60500-1.1	I180E	Pathogenic	0.67
NPHS1	O60500-1.1	I180F	Neutral	0.142
NPHS1	O60500-1.1	I180G	Pathogenic	0.69
NPHS1	O60500-1.1	I180H	Neutral	0.343
NPHS1	O60500-1.1	I180K	Pathogenic	0.757
NPHS1	O60500-1.1	I180L	Neutral	0.244
NPHS1	O60500-1.1	I180M	Neutral	0.304
NPHS1	O60500-1.1	I180N	Pathogenic	0.723
NPHS1	O60500-1.1	I180P	Neutral	0.297
NPHS1	O60500-1.1	I180Q	Neutral	0.492
NPHS1	O60500-1.1	I180R	Pathogenic	0.812
NPHS1	O60500-1.1	I180S	Pathogenic	0.743
NPHS1	O60500-1.1	I180T	Pathogenic	0.635
NPHS1	O60500-1.1	I180V	Pathogenic	0.608
NPHS1	O60500-1.1	I180W	Neutral	0.155
NPHS1	O60500-1.1	I180Y	Neutral	0.305
NPHS1	O60500-1.1	S181A	Neutral	0.057
NPHS1	O60500-1.1	S181C	Neutral	0.081
NPHS1	O60500-1.1	S181D	Neutral	0.088
NPHS1	O60500-1.1	S181E	Neutral	0.108
NPHS1	O60500-1.1	S181F	Neutral	0.384
NPHS1	O60500-1.1	S181G	Neutral	0.039
NPHS1	O60500-1.1	S181H	Neutral	0.05
NPHS1	O60500-1.1	S181I	Neutral	0.33
NPHS1	O60500-1.1	S181K	Neutral	0.275
NPHS1	O60500-1.1	S181L	Neutral	0.297
NPHS1	O60500-1.1	S181M	Neutral	0.239
NPHS1	O60500-1.1	S181N	Neutral	0.112
NPHS1	O60500-1.1	S181P	Neutral	0.061
NPHS1	O60500-1.1	S181Q	Neutral	0.068
NPHS1	O60500-1.1	S181R	Neutral	0.261
NPHS1	O60500-1.1	S181T	Neutral	0.073
NPHS1	O60500-1.1	S181V	Neutral	0.116
NPHS1	O60500-1.1	S181W	Pathogenic	0.617
NPHS1	O60500-1.1	S181Y	Neutral	0.173
NPHS1	O60500-1.1	D182A	Neutral	0.146
NPHS1	O60500-1.1	D182C	Neutral	0.166
NPHS1	O60500-1.1	D182E	Neutral	0.152
NPHS1	O60500-1.1	D182F	Pathogenic	0.624
NPHS1	O60500-1.1	D182G	Neutral	0.201
NPHS1	O60500-1.1	D182H	Neutral	0.174
NPHS1	O60500-1.1	D182I	Pathogenic	0.567
NPHS1	O60500-1.1	D182K	Neutral	0.102
NPHS1	O60500-1.1	D182L	Neutral	0.43
NPHS1	O60500-1.1	D182M	Neutral	0.359
NPHS1	O60500-1.1	D182N	Neutral	0.085
NPHS1	O60500-1.1	D182P	Neutral	0.214
NPHS1	O60500-1.1	D182Q	Neutral	0.145
NPHS1	O60500-1.1	D182R	Neutral	0.096
NPHS1	O60500-1.1	D182S	Neutral	0.165
NPHS1	O60500-1.1	D182T	Neutral	0.123
NPHS1	O60500-1.1	D182V	Neutral	0.259
NPHS1	O60500-1.1	D182W	Pathogenic	0.811
NPHS1	O60500-1.1	D182Y	Neutral	0.358
NPHS1	O60500-1.1	I183A	Pathogenic	0.642
NPHS1	O60500-1.1	I183C	Neutral	0.295
NPHS1	O60500-1.1	I183D	Pathogenic	0.694
NPHS1	O60500-1.1	I183E	Pathogenic	0.549
NPHS1	O60500-1.1	I183F	Neutral	0.09
NPHS1	O60500-1.1	I183G	Pathogenic	0.572
NPHS1	O60500-1.1	I183H	Neutral	0.239
NPHS1	O60500-1.1	I183K	Pathogenic	0.652
NPHS1	O60500-1.1	I183L	Neutral	0.163
NPHS1	O60500-1.1	I183M	Neutral	0.208
NPHS1	O60500-1.1	I183N	Pathogenic	0.611
NPHS1	O60500-1.1	I183P	Neutral	0.202
NPHS1	O60500-1.1	I183Q	Neutral	0.368
NPHS1	O60500-1.1	I183R	Pathogenic	0.722
NPHS1	O60500-1.1	I183S	Pathogenic	0.635
NPHS1	O60500-1.1	I183T	Pathogenic	0.511
NPHS1	O60500-1.1	I183V	Neutral	0.483
NPHS1	O60500-1.1	I183W	Neutral	0.1
NPHS1	O60500-1.1	I183Y	Neutral	0.208
NPHS1	O60500-1.1	S184A	Neutral	0.208
NPHS1	O60500-1.1	S184C	Neutral	0.276
NPHS1	O60500-1.1	S184D	Neutral	0.295
NPHS1	O60500-1.1	S184E	Neutral	0.344
NPHS1	O60500-1.1	S184F	Pathogenic	0.73
NPHS1	O60500-1.1	S184G	Neutral	0.149
NPHS1	O60500-1.1	S184H	Neutral	0.186
NPHS1	O60500-1.1	S184I	Pathogenic	0.68
NPHS1	O60500-1.1	S184K	Pathogenic	0.621
NPHS1	O60500-1.1	S184L	Pathogenic	0.646
NPHS1	O60500-1.1	S184M	Pathogenic	0.575
NPHS1	O60500-1.1	S184N	Neutral	0.353
NPHS1	O60500-1.1	S184P	Neutral	0.22
NPHS1	O60500-1.1	S184Q	Neutral	0.241
NPHS1	O60500-1.1	S184R	Pathogenic	0.604
NPHS1	O60500-1.1	S184T	Neutral	0.253
NPHS1	O60500-1.1	S184V	Neutral	0.362
NPHS1	O60500-1.1	S184W	Pathogenic	0.875
NPHS1	O60500-1.1	S184Y	Neutral	0.475
NPHS1	O60500-1.1	A185C	Neutral	0.019
NPHS1	O60500-1.1	A185D	Neutral	0.018
NPHS1	O60500-1.1	A185E	Neutral	0.033
NPHS1	O60500-1.1	A185F	Neutral	0.085
NPHS1	O60500-1.1	A185G	Neutral	0.011
NPHS1	O60500-1.1	A185H	Neutral	0.009
NPHS1	O60500-1.1	A185I	Neutral	0.099
NPHS1	O60500-1.1	A185K	Neutral	0.096
NPHS1	O60500-1.1	A185L	Neutral	0.086
NPHS1	O60500-1.1	A185M	Neutral	0.045
NPHS1	O60500-1.1	A185N	Neutral	0.016
NPHS1	O60500-1.1	A185P	Neutral	0.01
NPHS1	O60500-1.1	A185Q	Neutral	0.02
NPHS1	O60500-1.1	A185R	Neutral	0.128
NPHS1	O60500-1.1	A185S	Neutral	0.013
NPHS1	O60500-1.1	A185T	Neutral	0.009
NPHS1	O60500-1.1	A185V	Neutral	0.042
NPHS1	O60500-1.1	A185W	Neutral	0.194
NPHS1	O60500-1.1	A185Y	Neutral	0.03
NPHS1	O60500-1.1	N186A	Neutral	0.093
NPHS1	O60500-1.1	N186C	Neutral	0.107
NPHS1	O60500-1.1	N186D	Neutral	0.06
NPHS1	O60500-1.1	N186E	Neutral	0.041
NPHS1	O60500-1.1	N186F	Neutral	0.442
NPHS1	O60500-1.1	N186G	Neutral	0.185
NPHS1	O60500-1.1	N186H	Neutral	0.182
NPHS1	O60500-1.1	N186I	Neutral	0.384
NPHS1	O60500-1.1	N186K	Neutral	0.118
NPHS1	O60500-1.1	N186L	Neutral	0.348
NPHS1	O60500-1.1	N186M	Neutral	0.284
NPHS1	O60500-1.1	N186P	Neutral	0.099
NPHS1	O60500-1.1	N186Q	Neutral	0.074
NPHS1	O60500-1.1	N186R	Neutral	0.156
NPHS1	O60500-1.1	N186S	Neutral	0.15
NPHS1	O60500-1.1	N186T	Neutral	0.103
NPHS1	O60500-1.1	N186V	Neutral	0.142
NPHS1	O60500-1.1	N186W	Pathogenic	0.671
NPHS1	O60500-1.1	N186Y	Neutral	0.284
NPHS1	O60500-1.1	V187A	Neutral	0.475
NPHS1	O60500-1.1	V187C	Neutral	0.124
NPHS1	O60500-1.1	V187D	Neutral	0.435
NPHS1	O60500-1.1	V187E	Neutral	0.427
NPHS1	O60500-1.1	V187F	Neutral	0.233
NPHS1	O60500-1.1	V187G	Neutral	0.403
NPHS1	O60500-1.1	V187H	Neutral	0.164
NPHS1	O60500-1.1	V187I	Pathogenic	0.543
NPHS1	O60500-1.1	V187K	Pathogenic	0.699
NPHS1	O60500-1.1	V187L	Neutral	0.314
NPHS1	O60500-1.1	V187M	Neutral	0.185
NPHS1	O60500-1.1	V187N	Neutral	0.347
NPHS1	O60500-1.1	V187P	Neutral	0.114
NPHS1	O60500-1.1	V187Q	Neutral	0.31
NPHS1	O60500-1.1	V187R	Pathogenic	0.684
NPHS1	O60500-1.1	V187S	Neutral	0.371
NPHS1	O60500-1.1	V187T	Neutral	0.346
NPHS1	O60500-1.1	V187W	Neutral	0.345
NPHS1	O60500-1.1	V187Y	Neutral	0.18
NPHS1	O60500-1.1	N188A	Pathogenic	0.524
NPHS1	O60500-1.1	N188C	Pathogenic	0.563
NPHS1	O60500-1.1	N188D	Neutral	0.408
NPHS1	O60500-1.1	N188E	Neutral	0.314
NPHS1	O60500-1.1	N188F	Pathogenic	0.895
NPHS1	O60500-1.1	N188G	Pathogenic	0.708
NPHS1	O60500-1.1	N188H	Pathogenic	0.705
NPHS1	O60500-1.1	N188I	Pathogenic	0.87
NPHS1	O60500-1.1	N188K	Pathogenic	0.589
NPHS1	O60500-1.1	N188L	Pathogenic	0.852
NPHS1	O60500-1.1	N188M	Pathogenic	0.81
NPHS1	O60500-1.1	N188P	Pathogenic	0.541
NPHS1	O60500-1.1	N188Q	Neutral	0.463
NPHS1	O60500-1.1	N188R	Pathogenic	0.665
NPHS1	O60500-1.1	N188S	Pathogenic	0.655
NPHS1	O60500-1.1	N188T	Pathogenic	0.551
NPHS1	O60500-1.1	N188V	Pathogenic	0.641
NPHS1	O60500-1.1	N188W	Pathogenic	0.956
NPHS1	O60500-1.1	N188Y	Pathogenic	0.809
NPHS1	O60500-1.1	E189A	Neutral	0.037
NPHS1	O60500-1.1	E189C	Neutral	0.02
NPHS1	O60500-1.1	E189D	Neutral	0.021
NPHS1	O60500-1.1	E189F	Neutral	0.098
NPHS1	O60500-1.1	E189G	Neutral	0.025
NPHS1	O60500-1.1	E189H	Neutral	0.02
NPHS1	O60500-1.1	E189I	Neutral	0.079
NPHS1	O60500-1.1	E189K	Neutral	0.024
NPHS1	O60500-1.1	E189L	Neutral	0.068
NPHS1	O60500-1.1	E189M	Neutral	0.052
NPHS1	O60500-1.1	E189N	Neutral	0.007
NPHS1	O60500-1.1	E189P	Neutral	0.04
NPHS1	O60500-1.1	E189Q	Neutral	0.024
NPHS1	O60500-1.1	E189R	Neutral	0.022
NPHS1	O60500-1.1	E189S	Neutral	0.029
NPHS1	O60500-1.1	E189T	Neutral	0.019
NPHS1	O60500-1.1	E189V	Neutral	0.039
NPHS1	O60500-1.1	E189W	Neutral	0.295
NPHS1	O60500-1.1	E189Y	Neutral	0.052
NPHS1	O60500-1.1	G190A	Pathogenic	0.965
NPHS1	O60500-1.1	G190C	Pathogenic	0.973
NPHS1	O60500-1.1	G190D	Pathogenic	0.985
NPHS1	O60500-1.1	G190E	Pathogenic	0.982
NPHS1	O60500-1.1	G190F	Pathogenic	0.997
NPHS1	O60500-1.1	G190H	Pathogenic	0.97
NPHS1	O60500-1.1	G190I	Pathogenic	0.995
NPHS1	O60500-1.1	G190K	Pathogenic	0.994
NPHS1	O60500-1.1	G190L	Pathogenic	0.994
NPHS1	O60500-1.1	G190M	Pathogenic	0.992
NPHS1	O60500-1.1	G190N	Pathogenic	0.988
NPHS1	O60500-1.1	G190P	Pathogenic	0.975
NPHS1	O60500-1.1	G190Q	Pathogenic	0.971
NPHS1	O60500-1.1	G190R	Pathogenic	0.996
NPHS1	O60500-1.1	G190S	Pathogenic	0.955
NPHS1	O60500-1.1	G190T	Pathogenic	0.955
NPHS1	O60500-1.1	G190V	Pathogenic	0.988
NPHS1	O60500-1.1	G190W	Pathogenic	1.0
NPHS1	O60500-1.1	G190Y	Pathogenic	0.992
NPHS1	O60500-1.1	S191A	Pathogenic	0.958
NPHS1	O60500-1.1	S191C	Pathogenic	0.97
NPHS1	O60500-1.1	S191D	Pathogenic	0.973
NPHS1	O60500-1.1	S191E	Pathogenic	0.978
NPHS1	O60500-1.1	S191F	Pathogenic	0.996
NPHS1	O60500-1.1	S191G	Pathogenic	0.937
NPHS1	O60500-1.1	S191H	Pathogenic	0.951
NPHS1	O60500-1.1	S191I	Pathogenic	0.995
NPHS1	O60500-1.1	S191K	Pathogenic	0.993
NPHS1	O60500-1.1	S191L	Pathogenic	0.994
NPHS1	O60500-1.1	S191M	Pathogenic	0.991
NPHS1	O60500-1.1	S191N	Pathogenic	0.979
NPHS1	O60500-1.1	S191P	Pathogenic	0.96
NPHS1	O60500-1.1	S191Q	Pathogenic	0.965
NPHS1	O60500-1.1	S191R	Pathogenic	0.992
NPHS1	O60500-1.1	S191T	Pathogenic	0.967
NPHS1	O60500-1.1	S191V	Pathogenic	0.98
NPHS1	O60500-1.1	S191W	Pathogenic	0.998
NPHS1	O60500-1.1	S191Y	Pathogenic	0.987
NPHS1	O60500-1.1	Q192A	Neutral	0.118
NPHS1	O60500-1.1	Q192C	Neutral	0.095
NPHS1	O60500-1.1	Q192D	Neutral	0.105
NPHS1	O60500-1.1	Q192E	Neutral	0.123
NPHS1	O60500-1.1	Q192F	Neutral	0.228
NPHS1	O60500-1.1	Q192G	Neutral	0.082
NPHS1	O60500-1.1	Q192H	Neutral	0.053
NPHS1	O60500-1.1	Q192I	Neutral	0.189
NPHS1	O60500-1.1	Q192K	Neutral	0.188
NPHS1	O60500-1.1	Q192L	Neutral	0.23
NPHS1	O60500-1.1	Q192M	Neutral	0.248
NPHS1	O60500-1.1	Q192N	Neutral	0.075
NPHS1	O60500-1.1	Q192P	Neutral	0.125
NPHS1	O60500-1.1	Q192R	Neutral	0.243
NPHS1	O60500-1.1	Q192S	Neutral	0.094
NPHS1	O60500-1.1	Q192T	Neutral	0.063
NPHS1	O60500-1.1	Q192V	Neutral	0.124
NPHS1	O60500-1.1	Q192W	Pathogenic	0.629
NPHS1	O60500-1.1	Q192Y	Neutral	0.181
NPHS1	O60500-1.1	Q193A	Neutral	0.092
NPHS1	O60500-1.1	Q193C	Neutral	0.074
NPHS1	O60500-1.1	Q193D	Neutral	0.081
NPHS1	O60500-1.1	Q193E	Neutral	0.096
NPHS1	O60500-1.1	Q193F	Neutral	0.183
NPHS1	O60500-1.1	Q193G	Neutral	0.063
NPHS1	O60500-1.1	Q193H	Neutral	0.04
NPHS1	O60500-1.1	Q193I	Neutral	0.15
NPHS1	O60500-1.1	Q193K	Neutral	0.149
NPHS1	O60500-1.1	Q193L	Neutral	0.184
NPHS1	O60500-1.1	Q193M	Neutral	0.2
NPHS1	O60500-1.1	Q193N	Neutral	0.058
NPHS1	O60500-1.1	Q193P	Neutral	0.098
NPHS1	O60500-1.1	Q193R	Neutral	0.195
NPHS1	O60500-1.1	Q193S	Neutral	0.073
NPHS1	O60500-1.1	Q193T	Neutral	0.048
NPHS1	O60500-1.1	Q193V	Neutral	0.097
NPHS1	O60500-1.1	Q193W	Pathogenic	0.562
NPHS1	O60500-1.1	Q193Y	Neutral	0.143
NPHS1	O60500-1.1	K194A	Pathogenic	0.999
NPHS1	O60500-1.1	K194C	Pathogenic	0.998
NPHS1	O60500-1.1	K194D	Pathogenic	0.988
NPHS1	O60500-1.1	K194E	Pathogenic	0.993
NPHS1	O60500-1.1	K194F	Pathogenic	0.998
NPHS1	O60500-1.1	K194G	Pathogenic	0.998
NPHS1	O60500-1.1	K194H	Pathogenic	0.994
NPHS1	O60500-1.1	K194I	Pathogenic	0.999
NPHS1	O60500-1.1	K194L	Pathogenic	0.999
NPHS1	O60500-1.1	K194M	Pathogenic	0.999
NPHS1	O60500-1.1	K194N	Pathogenic	0.993
NPHS1	O60500-1.1	K194P	Pathogenic	0.999
NPHS1	O60500-1.1	K194Q	Pathogenic	0.996
NPHS1	O60500-1.1	K194R	Pathogenic	0.99
NPHS1	O60500-1.1	K194S	Pathogenic	0.998
NPHS1	O60500-1.1	K194T	Pathogenic	0.997
NPHS1	O60500-1.1	K194V	Pathogenic	0.999
NPHS1	O60500-1.1	K194W	Pathogenic	1.0
NPHS1	O60500-1.1	K194Y	Pathogenic	0.997
NPHS1	O60500-1.1	L195A	Pathogenic	0.981
NPHS1	O60500-1.1	L195C	Pathogenic	0.925
NPHS1	O60500-1.1	L195D	Pathogenic	0.978
NPHS1	O60500-1.1	L195E	Pathogenic	0.973
NPHS1	O60500-1.1	L195F	Pathogenic	0.792
NPHS1	O60500-1.1	L195G	Pathogenic	0.975
NPHS1	O60500-1.1	L195H	Pathogenic	0.903
NPHS1	O60500-1.1	L195I	Pathogenic	0.87
NPHS1	O60500-1.1	L195K	Pathogenic	0.988
NPHS1	O60500-1.1	L195M	Pathogenic	0.92
NPHS1	O60500-1.1	L195N	Pathogenic	0.979
NPHS1	O60500-1.1	L195P	Pathogenic	0.882
NPHS1	O60500-1.1	L195Q	Pathogenic	0.962
NPHS1	O60500-1.1	L195R	Pathogenic	0.991
NPHS1	O60500-1.1	L195S	Pathogenic	0.981
NPHS1	O60500-1.1	L195T	Pathogenic	0.969
NPHS1	O60500-1.1	L195V	Pathogenic	0.925
NPHS1	O60500-1.1	L195W	Pathogenic	0.869
NPHS1	O60500-1.1	L195Y	Pathogenic	0.886
NPHS1	O60500-1.1	F196A	Pathogenic	0.916
NPHS1	O60500-1.1	F196C	Pathogenic	0.718
NPHS1	O60500-1.1	F196D	Pathogenic	0.954
NPHS1	O60500-1.1	F196E	Pathogenic	0.917
NPHS1	O60500-1.1	F196G	Pathogenic	0.948
NPHS1	O60500-1.1	F196H	Pathogenic	0.863
NPHS1	O60500-1.1	F196I	Neutral	0.415
NPHS1	O60500-1.1	F196K	Pathogenic	0.91
NPHS1	O60500-1.1	F196L	Neutral	0.442
NPHS1	O60500-1.1	F196M	Pathogenic	0.614
NPHS1	O60500-1.1	F196N	Pathogenic	0.934
NPHS1	O60500-1.1	F196P	Pathogenic	0.606
NPHS1	O60500-1.1	F196Q	Pathogenic	0.84
NPHS1	O60500-1.1	F196R	Pathogenic	0.933
NPHS1	O60500-1.1	F196S	Pathogenic	0.94
NPHS1	O60500-1.1	F196T	Pathogenic	0.864
NPHS1	O60500-1.1	F196V	Pathogenic	0.631
NPHS1	O60500-1.1	F196W	Pathogenic	0.755
NPHS1	O60500-1.1	F196Y	Pathogenic	0.875
NPHS1	O60500-1.1	T197A	Neutral	0.018
NPHS1	O60500-1.1	T197C	Neutral	0.021
NPHS1	O60500-1.1	T197D	Neutral	0.029
NPHS1	O60500-1.1	T197E	Neutral	0.033
NPHS1	O60500-1.1	T197F	Neutral	0.098
NPHS1	O60500-1.1	T197G	Neutral	0.017
NPHS1	O60500-1.1	T197H	Neutral	0.009
NPHS1	O60500-1.1	T197I	Neutral	0.113
NPHS1	O60500-1.1	T197K	Neutral	0.096
NPHS1	O60500-1.1	T197L	Neutral	0.099
NPHS1	O60500-1.1	T197M	Neutral	0.052
NPHS1	O60500-1.1	T197N	Neutral	0.034
NPHS1	O60500-1.1	T197P	Neutral	0.013
NPHS1	O60500-1.1	T197Q	Neutral	0.02
NPHS1	O60500-1.1	T197R	Neutral	0.128
NPHS1	O60500-1.1	T197S	Neutral	0.033
NPHS1	O60500-1.1	T197V	Neutral	0.048
NPHS1	O60500-1.1	T197W	Neutral	0.295
NPHS1	O60500-1.1	T197Y	Neutral	0.035
NPHS1	O60500-1.1	V198A	Neutral	0.174
NPHS1	O60500-1.1	V198C	Neutral	0.032
NPHS1	O60500-1.1	V198D	Neutral	0.152
NPHS1	O60500-1.1	V198E	Neutral	0.148
NPHS1	O60500-1.1	V198F	Neutral	0.066
NPHS1	O60500-1.1	V198G	Neutral	0.136
NPHS1	O60500-1.1	V198H	Neutral	0.044
NPHS1	O60500-1.1	V198I	Neutral	0.217
NPHS1	O60500-1.1	V198K	Neutral	0.352
NPHS1	O60500-1.1	V198L	Neutral	0.096
NPHS1	O60500-1.1	V198M	Neutral	0.05
NPHS1	O60500-1.1	V198N	Neutral	0.11
NPHS1	O60500-1.1	V198P	Neutral	0.029
NPHS1	O60500-1.1	V198Q	Neutral	0.095
NPHS1	O60500-1.1	V198R	Neutral	0.336
NPHS1	O60500-1.1	V198S	Neutral	0.121
NPHS1	O60500-1.1	V198T	Neutral	0.11
NPHS1	O60500-1.1	V198W	Neutral	0.109
NPHS1	O60500-1.1	V198Y	Neutral	0.049
NPHS1	O60500-1.1	E199A	Pathogenic	0.807
NPHS1	O60500-1.1	E199C	Pathogenic	0.688
NPHS1	O60500-1.1	E199D	Pathogenic	0.702
NPHS1	O60500-1.1	E199F	Pathogenic	0.921
NPHS1	O60500-1.1	E199G	Pathogenic	0.736
NPHS1	O60500-1.1	E199H	Pathogenic	0.688
NPHS1	O60500-1.1	E199I	Pathogenic	0.902
NPHS1	O60500-1.1	E199K	Pathogenic	0.725
NPHS1	O60500-1.1	E199L	Pathogenic	0.888
NPHS1	O60500-1.1	E199M	Pathogenic	0.855
NPHS1	O60500-1.1	E199N	Neutral	0.449
NPHS1	O60500-1.1	E199P	Pathogenic	0.818
NPHS1	O60500-1.1	E199Q	Pathogenic	0.726
NPHS1	O60500-1.1	E199R	Pathogenic	0.711
NPHS1	O60500-1.1	E199S	Pathogenic	0.765
NPHS1	O60500-1.1	E199T	Pathogenic	0.678
NPHS1	O60500-1.1	E199V	Pathogenic	0.816
NPHS1	O60500-1.1	E199W	Pathogenic	0.978
NPHS1	O60500-1.1	E199Y	Pathogenic	0.854
NPHS1	O60500-1.1	A200C	Pathogenic	0.848
NPHS1	O60500-1.1	A200D	Pathogenic	0.837
NPHS1	O60500-1.1	A200E	Pathogenic	0.906
NPHS1	O60500-1.1	A200F	Pathogenic	0.964
NPHS1	O60500-1.1	A200G	Pathogenic	0.763
NPHS1	O60500-1.1	A200H	Pathogenic	0.717
NPHS1	O60500-1.1	A200I	Pathogenic	0.969
NPHS1	O60500-1.1	A200K	Pathogenic	0.968
NPHS1	O60500-1.1	A200L	Pathogenic	0.964
NPHS1	O60500-1.1	A200M	Pathogenic	0.93
NPHS1	O60500-1.1	A200N	Pathogenic	0.818
NPHS1	O60500-1.1	A200P	Pathogenic	0.735
NPHS1	O60500-1.1	A200Q	Pathogenic	0.853
NPHS1	O60500-1.1	A200R	Pathogenic	0.977
NPHS1	O60500-1.1	A200S	Pathogenic	0.789
NPHS1	O60500-1.1	A200T	Pathogenic	0.722
NPHS1	O60500-1.1	A200V	Pathogenic	0.925
NPHS1	O60500-1.1	A200W	Pathogenic	0.986
NPHS1	O60500-1.1	A200Y	Pathogenic	0.899
NPHS1	O60500-1.1	T201A	Neutral	0.1
NPHS1	O60500-1.1	T201C	Neutral	0.114
NPHS1	O60500-1.1	T201D	Neutral	0.152
NPHS1	O60500-1.1	T201E	Neutral	0.17
NPHS1	O60500-1.1	T201F	Neutral	0.397
NPHS1	O60500-1.1	T201G	Neutral	0.096
NPHS1	O60500-1.1	T201H	Neutral	0.051
NPHS1	O60500-1.1	T201I	Neutral	0.436
NPHS1	O60500-1.1	T201K	Neutral	0.391
NPHS1	O60500-1.1	T201L	Neutral	0.399
NPHS1	O60500-1.1	T201M	Neutral	0.248
NPHS1	O60500-1.1	T201N	Neutral	0.176
NPHS1	O60500-1.1	T201P	Neutral	0.074
NPHS1	O60500-1.1	T201Q	Neutral	0.11
NPHS1	O60500-1.1	T201R	Neutral	0.471
NPHS1	O60500-1.1	T201S	Neutral	0.17
NPHS1	O60500-1.1	T201V	Neutral	0.235
NPHS1	O60500-1.1	T201W	Pathogenic	0.717
NPHS1	O60500-1.1	T201Y	Neutral	0.181
NPHS1	O60500-1.1	A202C	Neutral	0.152
NPHS1	O60500-1.1	A202D	Neutral	0.141
NPHS1	O60500-1.1	A202E	Neutral	0.236
NPHS1	O60500-1.1	A202F	Neutral	0.459
NPHS1	O60500-1.1	A202G	Neutral	0.094
NPHS1	O60500-1.1	A202H	Neutral	0.075
NPHS1	O60500-1.1	A202I	Neutral	0.5
NPHS1	O60500-1.1	A202K	Neutral	0.491
NPHS1	O60500-1.1	A202L	Neutral	0.461
NPHS1	O60500-1.1	A202M	Neutral	0.299
NPHS1	O60500-1.1	A202N	Neutral	0.126
NPHS1	O60500-1.1	A202P	Neutral	0.082
NPHS1	O60500-1.1	A202Q	Neutral	0.157
NPHS1	O60500-1.1	A202R	Pathogenic	0.573
NPHS1	O60500-1.1	A202S	Neutral	0.107
NPHS1	O60500-1.1	A202T	Neutral	0.077
NPHS1	O60500-1.1	A202V	Neutral	0.284
NPHS1	O60500-1.1	A202W	Pathogenic	0.687
NPHS1	O60500-1.1	A202Y	Neutral	0.222
NPHS1	O60500-1.1	R203A	Pathogenic	0.976
NPHS1	O60500-1.1	R203C	Pathogenic	0.97
NPHS1	O60500-1.1	R203D	Pathogenic	0.76
NPHS1	O60500-1.1	R203E	Pathogenic	0.848
NPHS1	O60500-1.1	R203F	Pathogenic	0.971
NPHS1	O60500-1.1	R203G	Pathogenic	0.965
NPHS1	O60500-1.1	R203H	Pathogenic	0.934
NPHS1	O60500-1.1	R203I	Pathogenic	0.978
NPHS1	O60500-1.1	R203K	Pathogenic	0.799
NPHS1	O60500-1.1	R203L	Pathogenic	0.983
NPHS1	O60500-1.1	R203M	Pathogenic	0.977
NPHS1	O60500-1.1	R203N	Pathogenic	0.889
NPHS1	O60500-1.1	R203P	Pathogenic	0.967
NPHS1	O60500-1.1	R203Q	Pathogenic	0.932
NPHS1	O60500-1.1	R203S	Pathogenic	0.956
NPHS1	O60500-1.1	R203T	Pathogenic	0.954
NPHS1	O60500-1.1	R203V	Pathogenic	0.967
NPHS1	O60500-1.1	R203W	Pathogenic	0.986
NPHS1	O60500-1.1	R203Y	Pathogenic	0.927
NPHS1	O60500-1.1	V204A	Pathogenic	0.888
NPHS1	O60500-1.1	V204C	Pathogenic	0.555
NPHS1	O60500-1.1	V204D	Pathogenic	0.871
NPHS1	O60500-1.1	V204E	Pathogenic	0.867
NPHS1	O60500-1.1	V204F	Pathogenic	0.728
NPHS1	O60500-1.1	V204G	Pathogenic	0.856
NPHS1	O60500-1.1	V204H	Pathogenic	0.633
NPHS1	O60500-1.1	V204I	Pathogenic	0.912
NPHS1	O60500-1.1	V204K	Pathogenic	0.953
NPHS1	O60500-1.1	V204L	Pathogenic	0.801
NPHS1	O60500-1.1	V204M	Pathogenic	0.667
NPHS1	O60500-1.1	V204N	Pathogenic	0.824
NPHS1	O60500-1.1	V204P	Pathogenic	0.53
NPHS1	O60500-1.1	V204Q	Pathogenic	0.798
NPHS1	O60500-1.1	V204R	Pathogenic	0.95
NPHS1	O60500-1.1	V204S	Pathogenic	0.838
NPHS1	O60500-1.1	V204T	Pathogenic	0.823
NPHS1	O60500-1.1	V204W	Pathogenic	0.822
NPHS1	O60500-1.1	V204Y	Pathogenic	0.658
NPHS1	O60500-1.1	T205A	Pathogenic	0.613
NPHS1	O60500-1.1	T205C	Pathogenic	0.649
NPHS1	O60500-1.1	T205D	Pathogenic	0.72
NPHS1	O60500-1.1	T205E	Pathogenic	0.746
NPHS1	O60500-1.1	T205F	Pathogenic	0.904
NPHS1	O60500-1.1	T205G	Pathogenic	0.602
NPHS1	O60500-1.1	T205H	Neutral	0.436
NPHS1	O60500-1.1	T205I	Pathogenic	0.917
NPHS1	O60500-1.1	T205K	Pathogenic	0.902
NPHS1	O60500-1.1	T205L	Pathogenic	0.905
NPHS1	O60500-1.1	T205M	Pathogenic	0.825
NPHS1	O60500-1.1	T205N	Pathogenic	0.753
NPHS1	O60500-1.1	T205P	Pathogenic	0.531
NPHS1	O60500-1.1	T205Q	Pathogenic	0.64
NPHS1	O60500-1.1	T205R	Pathogenic	0.927
NPHS1	O60500-1.1	T205S	Pathogenic	0.746
NPHS1	O60500-1.1	T205V	Pathogenic	0.815
NPHS1	O60500-1.1	T205W	Pathogenic	0.973
NPHS1	O60500-1.1	T205Y	Pathogenic	0.759
NPHS1	O60500-1.1	P206A	Pathogenic	0.683
NPHS1	O60500-1.1	P206C	Neutral	0.332
NPHS1	O60500-1.1	P206D	Pathogenic	0.864
NPHS1	O60500-1.1	P206E	Pathogenic	0.889
NPHS1	O60500-1.1	P206F	Pathogenic	0.744
NPHS1	O60500-1.1	P206G	Pathogenic	0.781
NPHS1	O60500-1.1	P206H	Pathogenic	0.679
NPHS1	O60500-1.1	P206I	Pathogenic	0.774
NPHS1	O60500-1.1	P206K	Pathogenic	0.961
NPHS1	O60500-1.1	P206L	Pathogenic	0.746
NPHS1	O60500-1.1	P206M	Pathogenic	0.686
NPHS1	O60500-1.1	P206N	Pathogenic	0.789
NPHS1	O60500-1.1	P206Q	Pathogenic	0.829
NPHS1	O60500-1.1	P206R	Pathogenic	0.959
NPHS1	O60500-1.1	P206S	Pathogenic	0.757
NPHS1	O60500-1.1	P206T	Pathogenic	0.592
NPHS1	O60500-1.1	P206V	Pathogenic	0.577
NPHS1	O60500-1.1	P206W	Pathogenic	0.918
NPHS1	O60500-1.1	P206Y	Pathogenic	0.593
NPHS1	O60500-1.1	R207A	Neutral	0.184
NPHS1	O60500-1.1	R207C	Neutral	0.15
NPHS1	O60500-1.1	R207D	Neutral	0.017
NPHS1	O60500-1.1	R207E	Neutral	0.03
NPHS1	O60500-1.1	R207F	Neutral	0.156
NPHS1	O60500-1.1	R207G	Neutral	0.131
NPHS1	O60500-1.1	R207H	Neutral	0.072
NPHS1	O60500-1.1	R207I	Neutral	0.197
NPHS1	O60500-1.1	R207K	Neutral	0.021
NPHS1	O60500-1.1	R207L	Neutral	0.239
NPHS1	O60500-1.1	R207M	Neutral	0.189
NPHS1	O60500-1.1	R207N	Neutral	0.042
NPHS1	O60500-1.1	R207P	Neutral	0.14
NPHS1	O60500-1.1	R207Q	Neutral	0.07
NPHS1	O60500-1.1	R207S	Neutral	0.105
NPHS1	O60500-1.1	R207T	Neutral	0.102
NPHS1	O60500-1.1	R207V	Neutral	0.138
NPHS1	O60500-1.1	R207W	Neutral	0.278
NPHS1	O60500-1.1	R207Y	Neutral	0.065
NPHS1	O60500-1.1	S208A	Pathogenic	0.788
NPHS1	O60500-1.1	S208C	Pathogenic	0.843
NPHS1	O60500-1.1	S208D	Pathogenic	0.855
NPHS1	O60500-1.1	S208E	Pathogenic	0.881
NPHS1	O60500-1.1	S208F	Pathogenic	0.974
NPHS1	O60500-1.1	S208G	Pathogenic	0.711
NPHS1	O60500-1.1	S208H	Pathogenic	0.763
NPHS1	O60500-1.1	S208I	Pathogenic	0.968
NPHS1	O60500-1.1	S208K	Pathogenic	0.959
NPHS1	O60500-1.1	S208L	Pathogenic	0.963
NPHS1	O60500-1.1	S208M	Pathogenic	0.95
NPHS1	O60500-1.1	S208N	Pathogenic	0.885
NPHS1	O60500-1.1	S208P	Pathogenic	0.799
NPHS1	O60500-1.1	S208Q	Pathogenic	0.817
NPHS1	O60500-1.1	S208R	Pathogenic	0.956
NPHS1	O60500-1.1	S208T	Pathogenic	0.827
NPHS1	O60500-1.1	S208V	Pathogenic	0.889
NPHS1	O60500-1.1	S208W	Pathogenic	0.99
NPHS1	O60500-1.1	S208Y	Pathogenic	0.927
NPHS1	O60500-1.1	S209A	Pathogenic	0.665
NPHS1	O60500-1.1	S209C	Pathogenic	0.742
NPHS1	O60500-1.1	S209D	Pathogenic	0.759
NPHS1	O60500-1.1	S209E	Pathogenic	0.799
NPHS1	O60500-1.1	S209F	Pathogenic	0.953
NPHS1	O60500-1.1	S209G	Pathogenic	0.569
NPHS1	O60500-1.1	S209H	Pathogenic	0.633
NPHS1	O60500-1.1	S209I	Pathogenic	0.941
NPHS1	O60500-1.1	S209K	Pathogenic	0.925
NPHS1	O60500-1.1	S209L	Pathogenic	0.932
NPHS1	O60500-1.1	S209M	Pathogenic	0.911
NPHS1	O60500-1.1	S209N	Pathogenic	0.805
NPHS1	O60500-1.1	S209P	Pathogenic	0.681
NPHS1	O60500-1.1	S209Q	Pathogenic	0.706
NPHS1	O60500-1.1	S209R	Pathogenic	0.92
NPHS1	O60500-1.1	S209T	Pathogenic	0.719
NPHS1	O60500-1.1	S209V	Pathogenic	0.811
NPHS1	O60500-1.1	S209W	Pathogenic	0.981
NPHS1	O60500-1.1	S209Y	Pathogenic	0.873
NPHS1	O60500-1.1	D210A	Pathogenic	0.991
NPHS1	O60500-1.1	D210C	Pathogenic	0.992
NPHS1	O60500-1.1	D210E	Pathogenic	0.992
NPHS1	O60500-1.1	D210F	Pathogenic	0.999
NPHS1	O60500-1.1	D210G	Pathogenic	0.994
NPHS1	O60500-1.1	D210H	Pathogenic	0.993
NPHS1	O60500-1.1	D210I	Pathogenic	0.999
NPHS1	O60500-1.1	D210K	Pathogenic	0.987
NPHS1	O60500-1.1	D210L	Pathogenic	0.998
NPHS1	O60500-1.1	D210M	Pathogenic	0.997
NPHS1	O60500-1.1	D210N	Pathogenic	0.984
NPHS1	O60500-1.1	D210P	Pathogenic	0.994
NPHS1	O60500-1.1	D210Q	Pathogenic	0.991
NPHS1	O60500-1.1	D210R	Pathogenic	0.986
NPHS1	O60500-1.1	D210S	Pathogenic	0.992
NPHS1	O60500-1.1	D210T	Pathogenic	0.989
NPHS1	O60500-1.1	D210V	Pathogenic	0.996
NPHS1	O60500-1.1	D210W	Pathogenic	1.0
NPHS1	O60500-1.1	D210Y	Pathogenic	0.997
NPHS1	O60500-1.1	N211A	Pathogenic	0.982
NPHS1	O60500-1.1	N211C	Pathogenic	0.985
NPHS1	O60500-1.1	N211D	Pathogenic	0.972
NPHS1	O60500-1.1	N211E	Pathogenic	0.959
NPHS1	O60500-1.1	N211F	Pathogenic	0.998
NPHS1	O60500-1.1	N211G	Pathogenic	0.992
NPHS1	O60500-1.1	N211H	Pathogenic	0.992
NPHS1	O60500-1.1	N211I	Pathogenic	0.997
NPHS1	O60500-1.1	N211K	Pathogenic	0.986
NPHS1	O60500-1.1	N211L	Pathogenic	0.997
NPHS1	O60500-1.1	N211M	Pathogenic	0.995
NPHS1	O60500-1.1	N211P	Pathogenic	0.984
NPHS1	O60500-1.1	N211Q	Pathogenic	0.978
NPHS1	O60500-1.1	N211R	Pathogenic	0.99
NPHS1	O60500-1.1	N211S	Pathogenic	0.99
NPHS1	O60500-1.1	N211T	Pathogenic	0.984
NPHS1	O60500-1.1	N211V	Pathogenic	0.989
NPHS1	O60500-1.1	N211W	Pathogenic	0.999
NPHS1	O60500-1.1	N211Y	Pathogenic	0.995
NPHS1	O60500-1.1	R212A	Pathogenic	0.573
NPHS1	O60500-1.1	R212C	Pathogenic	0.513
NPHS1	O60500-1.1	R212D	Neutral	0.093
NPHS1	O60500-1.1	R212E	Neutral	0.154
NPHS1	O60500-1.1	R212F	Pathogenic	0.523
NPHS1	O60500-1.1	R212G	Neutral	0.472
NPHS1	O60500-1.1	R212H	Neutral	0.316
NPHS1	O60500-1.1	R212I	Pathogenic	0.593
NPHS1	O60500-1.1	R212K	Neutral	0.115
NPHS1	O60500-1.1	R212L	Pathogenic	0.651
NPHS1	O60500-1.1	R212M	Pathogenic	0.58
NPHS1	O60500-1.1	R212N	Neutral	0.207
NPHS1	O60500-1.1	R212P	Neutral	0.491
NPHS1	O60500-1.1	R212Q	Neutral	0.31
NPHS1	O60500-1.1	R212S	Neutral	0.411
NPHS1	O60500-1.1	R212T	Neutral	0.402
NPHS1	O60500-1.1	R212V	Neutral	0.488
NPHS1	O60500-1.1	R212W	Pathogenic	0.696
NPHS1	O60500-1.1	R212Y	Neutral	0.293
NPHS1	O60500-1.1	Q213A	Pathogenic	0.637
NPHS1	O60500-1.1	Q213C	Pathogenic	0.579
NPHS1	O60500-1.1	Q213D	Pathogenic	0.605
NPHS1	O60500-1.1	Q213E	Pathogenic	0.647
NPHS1	O60500-1.1	Q213F	Pathogenic	0.794
NPHS1	O60500-1.1	Q213G	Pathogenic	0.538
NPHS1	O60500-1.1	Q213H	Neutral	0.422
NPHS1	O60500-1.1	Q213I	Pathogenic	0.753
NPHS1	O60500-1.1	Q213K	Pathogenic	0.752
NPHS1	O60500-1.1	Q213L	Pathogenic	0.796
NPHS1	O60500-1.1	Q213M	Pathogenic	0.812
NPHS1	O60500-1.1	Q213N	Pathogenic	0.514
NPHS1	O60500-1.1	Q213P	Pathogenic	0.652
NPHS1	O60500-1.1	Q213R	Pathogenic	0.808
NPHS1	O60500-1.1	Q213S	Pathogenic	0.576
NPHS1	O60500-1.1	Q213T	Neutral	0.468
NPHS1	O60500-1.1	Q213V	Pathogenic	0.65
NPHS1	O60500-1.1	Q213W	Pathogenic	0.957
NPHS1	O60500-1.1	Q213Y	Pathogenic	0.743
NPHS1	O60500-1.1	L214A	Pathogenic	0.537
NPHS1	O60500-1.1	L214C	Neutral	0.213
NPHS1	O60500-1.1	L214D	Neutral	0.496
NPHS1	O60500-1.1	L214E	Neutral	0.441
NPHS1	O60500-1.1	L214F	Neutral	0.077
NPHS1	O60500-1.1	L214G	Neutral	0.464
NPHS1	O60500-1.1	L214H	Neutral	0.169
NPHS1	O60500-1.1	L214I	Neutral	0.128
NPHS1	O60500-1.1	L214K	Pathogenic	0.644
NPHS1	O60500-1.1	L214M	Neutral	0.202
NPHS1	O60500-1.1	L214N	Pathogenic	0.504
NPHS1	O60500-1.1	L214P	Neutral	0.141
NPHS1	O60500-1.1	L214Q	Neutral	0.36
NPHS1	O60500-1.1	L214R	Pathogenic	0.715
NPHS1	O60500-1.1	L214S	Pathogenic	0.53
NPHS1	O60500-1.1	L214T	Neutral	0.404
NPHS1	O60500-1.1	L214V	Neutral	0.214
NPHS1	O60500-1.1	L214W	Neutral	0.127
NPHS1	O60500-1.1	L214Y	Neutral	0.146
NPHS1	O60500-1.1	L215A	Pathogenic	0.984
NPHS1	O60500-1.1	L215C	Pathogenic	0.936
NPHS1	O60500-1.1	L215D	Pathogenic	0.982
NPHS1	O60500-1.1	L215E	Pathogenic	0.977
NPHS1	O60500-1.1	L215F	Pathogenic	0.819
NPHS1	O60500-1.1	L215G	Pathogenic	0.979
NPHS1	O60500-1.1	L215H	Pathogenic	0.917
NPHS1	O60500-1.1	L215I	Pathogenic	0.888
NPHS1	O60500-1.1	L215K	Pathogenic	0.99
NPHS1	O60500-1.1	L215M	Pathogenic	0.932
NPHS1	O60500-1.1	L215N	Pathogenic	0.982
NPHS1	O60500-1.1	L215P	Pathogenic	0.899
NPHS1	O60500-1.1	L215Q	Pathogenic	0.968
NPHS1	O60500-1.1	L215R	Pathogenic	0.993
NPHS1	O60500-1.1	L215S	Pathogenic	0.984
NPHS1	O60500-1.1	L215T	Pathogenic	0.973
NPHS1	O60500-1.1	L215V	Pathogenic	0.936
NPHS1	O60500-1.1	L215W	Pathogenic	0.887
NPHS1	O60500-1.1	L215Y	Pathogenic	0.902
NPHS1	O60500-1.1	V216A	Neutral	0.462
NPHS1	O60500-1.1	V216C	Neutral	0.119
NPHS1	O60500-1.1	V216D	Neutral	0.422
NPHS1	O60500-1.1	V216E	Neutral	0.414
NPHS1	O60500-1.1	V216F	Neutral	0.224
NPHS1	O60500-1.1	V216G	Neutral	0.39
NPHS1	O60500-1.1	V216H	Neutral	0.157
NPHS1	O60500-1.1	V216I	Pathogenic	0.529
NPHS1	O60500-1.1	V216K	Pathogenic	0.688
NPHS1	O60500-1.1	V216L	Neutral	0.302
NPHS1	O60500-1.1	V216M	Neutral	0.177
NPHS1	O60500-1.1	V216N	Neutral	0.335
NPHS1	O60500-1.1	V216P	Neutral	0.108
NPHS1	O60500-1.1	V216Q	Neutral	0.299
NPHS1	O60500-1.1	V216R	Pathogenic	0.672
NPHS1	O60500-1.1	V216S	Neutral	0.358
NPHS1	O60500-1.1	V216T	Neutral	0.334
NPHS1	O60500-1.1	V216W	Neutral	0.333
NPHS1	O60500-1.1	V216Y	Neutral	0.172
NPHS1	O60500-1.1	C217A	Pathogenic	0.96
NPHS1	O60500-1.1	C217D	Pathogenic	0.963
NPHS1	O60500-1.1	C217E	Pathogenic	0.956
NPHS1	O60500-1.1	C217F	Pathogenic	0.964
NPHS1	O60500-1.1	C217G	Pathogenic	0.947
NPHS1	O60500-1.1	C217H	Pathogenic	0.928
NPHS1	O60500-1.1	C217I	Pathogenic	0.969
NPHS1	O60500-1.1	C217K	Pathogenic	0.99
NPHS1	O60500-1.1	C217L	Pathogenic	0.964
NPHS1	O60500-1.1	C217M	Pathogenic	0.931
NPHS1	O60500-1.1	C217N	Pathogenic	0.958
NPHS1	O60500-1.1	C217P	Pathogenic	0.735
NPHS1	O60500-1.1	C217Q	Pathogenic	0.952
NPHS1	O60500-1.1	C217R	Pathogenic	0.993
NPHS1	O60500-1.1	C217S	Pathogenic	0.959
NPHS1	O60500-1.1	C217T	Pathogenic	0.929
NPHS1	O60500-1.1	C217V	Pathogenic	0.894
NPHS1	O60500-1.1	C217W	Pathogenic	0.99
NPHS1	O60500-1.1	C217Y	Pathogenic	0.906
NPHS1	O60500-1.1	E218A	Neutral	0.254
NPHS1	O60500-1.1	E218C	Neutral	0.152
NPHS1	O60500-1.1	E218D	Neutral	0.16
NPHS1	O60500-1.1	E218F	Neutral	0.488
NPHS1	O60500-1.1	E218G	Neutral	0.185
NPHS1	O60500-1.1	E218H	Neutral	0.152
NPHS1	O60500-1.1	E218I	Neutral	0.429
NPHS1	O60500-1.1	E218K	Neutral	0.177
NPHS1	O60500-1.1	E218L	Neutral	0.392
NPHS1	O60500-1.1	E218M	Neutral	0.323
NPHS1	O60500-1.1	E218N	Neutral	0.062
NPHS1	O60500-1.1	E218P	Neutral	0.267
NPHS1	O60500-1.1	E218Q	Neutral	0.177
NPHS1	O60500-1.1	E218R	Neutral	0.167
NPHS1	O60500-1.1	E218S	Neutral	0.209
NPHS1	O60500-1.1	E218T	Neutral	0.146
NPHS1	O60500-1.1	E218V	Neutral	0.265
NPHS1	O60500-1.1	E218W	Pathogenic	0.786
NPHS1	O60500-1.1	E218Y	Neutral	0.323
NPHS1	O60500-1.1	A219C	Neutral	0.096
NPHS1	O60500-1.1	A219D	Neutral	0.089
NPHS1	O60500-1.1	A219E	Neutral	0.155
NPHS1	O60500-1.1	A219F	Neutral	0.335
NPHS1	O60500-1.1	A219G	Neutral	0.058
NPHS1	O60500-1.1	A219H	Neutral	0.046
NPHS1	O60500-1.1	A219I	Neutral	0.372
NPHS1	O60500-1.1	A219K	Neutral	0.363
NPHS1	O60500-1.1	A219L	Neutral	0.337
NPHS1	O60500-1.1	A219M	Neutral	0.202
NPHS1	O60500-1.1	A219N	Neutral	0.079
NPHS1	O60500-1.1	A219P	Neutral	0.05
NPHS1	O60500-1.1	A219Q	Neutral	0.1
NPHS1	O60500-1.1	A219R	Neutral	0.442
NPHS1	O60500-1.1	A219S	Neutral	0.066
NPHS1	O60500-1.1	A219T	Neutral	0.047
NPHS1	O60500-1.1	A219V	Neutral	0.19
NPHS1	O60500-1.1	A219W	Pathogenic	0.565
NPHS1	O60500-1.1	A219Y	Neutral	0.145
NPHS1	O60500-1.1	S220A	Neutral	0.116
NPHS1	O60500-1.1	S220C	Neutral	0.159
NPHS1	O60500-1.1	S220D	Neutral	0.172
NPHS1	O60500-1.1	S220E	Neutral	0.207
NPHS1	O60500-1.1	S220F	Pathogenic	0.573
NPHS1	O60500-1.1	S220G	Neutral	0.08
NPHS1	O60500-1.1	S220H	Neutral	0.102
NPHS1	O60500-1.1	S220I	Pathogenic	0.514
NPHS1	O60500-1.1	S220K	Neutral	0.449
NPHS1	O60500-1.1	S220L	Neutral	0.476
NPHS1	O60500-1.1	S220M	Neutral	0.402
NPHS1	O60500-1.1	S220N	Neutral	0.213
NPHS1	O60500-1.1	S220P	Neutral	0.123
NPHS1	O60500-1.1	S220Q	Neutral	0.136
NPHS1	O60500-1.1	S220R	Neutral	0.431
NPHS1	O60500-1.1	S220T	Neutral	0.144
NPHS1	O60500-1.1	S220V	Neutral	0.22
NPHS1	O60500-1.1	S220W	Pathogenic	0.776
NPHS1	O60500-1.1	S220Y	Neutral	0.311
NPHS1	O60500-1.1	S221A	Neutral	0.425
NPHS1	O60500-1.1	S221C	Pathogenic	0.517
NPHS1	O60500-1.1	S221D	Pathogenic	0.54
NPHS1	O60500-1.1	S221E	Pathogenic	0.596
NPHS1	O60500-1.1	S221F	Pathogenic	0.884
NPHS1	O60500-1.1	S221G	Neutral	0.329
NPHS1	O60500-1.1	S221H	Neutral	0.391
NPHS1	O60500-1.1	S221I	Pathogenic	0.857
NPHS1	O60500-1.1	S221K	Pathogenic	0.822
NPHS1	O60500-1.1	S221L	Pathogenic	0.837
NPHS1	O60500-1.1	S221M	Pathogenic	0.792
NPHS1	O60500-1.1	S221N	Pathogenic	0.605
NPHS1	O60500-1.1	S221P	Neutral	0.443
NPHS1	O60500-1.1	S221Q	Neutral	0.471
NPHS1	O60500-1.1	S221R	Pathogenic	0.811
NPHS1	O60500-1.1	S221T	Neutral	0.488
NPHS1	O60500-1.1	S221V	Pathogenic	0.615
NPHS1	O60500-1.1	S221W	Pathogenic	0.951
NPHS1	O60500-1.1	S221Y	Pathogenic	0.718
NPHS1	O60500-1.1	P222A	Pathogenic	0.629
NPHS1	O60500-1.1	P222C	Neutral	0.281
NPHS1	O60500-1.1	P222D	Pathogenic	0.834
NPHS1	O60500-1.1	P222E	Pathogenic	0.863
NPHS1	O60500-1.1	P222F	Pathogenic	0.696
NPHS1	O60500-1.1	P222G	Pathogenic	0.738
NPHS1	O60500-1.1	P222H	Pathogenic	0.624
NPHS1	O60500-1.1	P222I	Pathogenic	0.729
NPHS1	O60500-1.1	P222K	Pathogenic	0.952
NPHS1	O60500-1.1	P222L	Pathogenic	0.698
NPHS1	O60500-1.1	P222M	Pathogenic	0.632
NPHS1	O60500-1.1	P222N	Pathogenic	0.746
NPHS1	O60500-1.1	P222Q	Pathogenic	0.792
NPHS1	O60500-1.1	P222R	Pathogenic	0.948
NPHS1	O60500-1.1	P222S	Pathogenic	0.711
NPHS1	O60500-1.1	P222T	Pathogenic	0.533
NPHS1	O60500-1.1	P222V	Pathogenic	0.517
NPHS1	O60500-1.1	P222W	Pathogenic	0.898
NPHS1	O60500-1.1	P222Y	Pathogenic	0.535
NPHS1	O60500-1.1	A223C	Pathogenic	0.954
NPHS1	O60500-1.1	A223D	Pathogenic	0.951
NPHS1	O60500-1.1	A223E	Pathogenic	0.973
NPHS1	O60500-1.1	A223F	Pathogenic	0.99
NPHS1	O60500-1.1	A223G	Pathogenic	0.923
NPHS1	O60500-1.1	A223H	Pathogenic	0.905
NPHS1	O60500-1.1	A223I	Pathogenic	0.991
NPHS1	O60500-1.1	A223K	Pathogenic	0.991
NPHS1	O60500-1.1	A223L	Pathogenic	0.99
NPHS1	O60500-1.1	A223M	Pathogenic	0.98
NPHS1	O60500-1.1	A223N	Pathogenic	0.944
NPHS1	O60500-1.1	A223P	Pathogenic	0.912
NPHS1	O60500-1.1	A223Q	Pathogenic	0.956
NPHS1	O60500-1.1	A223R	Pathogenic	0.994
NPHS1	O60500-1.1	A223S	Pathogenic	0.933
NPHS1	O60500-1.1	A223T	Pathogenic	0.907
NPHS1	O60500-1.1	A223V	Pathogenic	0.979
NPHS1	O60500-1.1	A223W	Pathogenic	0.996
NPHS1	O60500-1.1	A223Y	Pathogenic	0.971
NPHS1	O60500-1.1	L224A	Pathogenic	0.639
NPHS1	O60500-1.1	L224C	Neutral	0.293
NPHS1	O60500-1.1	L224D	Pathogenic	0.601
NPHS1	O60500-1.1	L224E	Pathogenic	0.547
NPHS1	O60500-1.1	L224F	Neutral	0.113
NPHS1	O60500-1.1	L224G	Pathogenic	0.57
NPHS1	O60500-1.1	L224H	Neutral	0.237
NPHS1	O60500-1.1	L224I	Neutral	0.183
NPHS1	O60500-1.1	L224K	Pathogenic	0.734
NPHS1	O60500-1.1	L224M	Neutral	0.279
NPHS1	O60500-1.1	L224N	Pathogenic	0.608
NPHS1	O60500-1.1	L224P	Neutral	0.201
NPHS1	O60500-1.1	L224Q	Neutral	0.462
NPHS1	O60500-1.1	L224R	Pathogenic	0.793
NPHS1	O60500-1.1	L224S	Pathogenic	0.633
NPHS1	O60500-1.1	L224T	Pathogenic	0.508
NPHS1	O60500-1.1	L224V	Neutral	0.293
NPHS1	O60500-1.1	L224W	Neutral	0.181
NPHS1	O60500-1.1	L224Y	Neutral	0.207
NPHS1	O60500-1.1	E225A	Neutral	0.002
NPHS1	O60500-1.1	E225C	Neutral	0.001
NPHS1	O60500-1.1	E225D	Neutral	0.001
NPHS1	O60500-1.1	E225F	Neutral	0.005
NPHS1	O60500-1.1	E225G	Neutral	0.001
NPHS1	O60500-1.1	E225H	Neutral	0.001
NPHS1	O60500-1.1	E225I	Neutral	0.004
NPHS1	O60500-1.1	E225K	Neutral	0.001
NPHS1	O60500-1.1	E225L	Neutral	0.004
NPHS1	O60500-1.1	E225M	Neutral	0.003
NPHS1	O60500-1.1	E225N	Neutral	0.0
NPHS1	O60500-1.1	E225P	Neutral	0.002
NPHS1	O60500-1.1	E225Q	Neutral	0.001
NPHS1	O60500-1.1	E225R	Neutral	0.001
NPHS1	O60500-1.1	E225S	Neutral	0.002
NPHS1	O60500-1.1	E225T	Neutral	0.001
NPHS1	O60500-1.1	E225V	Neutral	0.002
NPHS1	O60500-1.1	E225W	Neutral	0.021
NPHS1	O60500-1.1	E225Y	Neutral	0.003
NPHS1	O60500-1.1	A226C	Neutral	0.001
NPHS1	O60500-1.1	A226D	Neutral	0.001
NPHS1	O60500-1.1	A226E	Neutral	0.002
NPHS1	O60500-1.1	A226F	Neutral	0.007
NPHS1	O60500-1.1	A226G	Neutral	0.001
NPHS1	O60500-1.1	A226H	Neutral	0.001
NPHS1	O60500-1.1	A226I	Neutral	0.008
NPHS1	O60500-1.1	A226K	Neutral	0.008
NPHS1	O60500-1.1	A226L	Neutral	0.007
NPHS1	O60500-1.1	A226M	Neutral	0.003
NPHS1	O60500-1.1	A226N	Neutral	0.001
NPHS1	O60500-1.1	A226P	Neutral	0.001
NPHS1	O60500-1.1	A226Q	Neutral	0.001
NPHS1	O60500-1.1	A226R	Neutral	0.01
NPHS1	O60500-1.1	A226S	Neutral	0.001
NPHS1	O60500-1.1	A226T	Neutral	0.001
NPHS1	O60500-1.1	A226V	Neutral	0.003
NPHS1	O60500-1.1	A226W	Neutral	0.017
NPHS1	O60500-1.1	A226Y	Neutral	0.002
NPHS1	O60500-1.1	P227A	Pathogenic	0.912
NPHS1	O60500-1.1	P227C	Pathogenic	0.706
NPHS1	O60500-1.1	P227D	Pathogenic	0.968
NPHS1	O60500-1.1	P227E	Pathogenic	0.975
NPHS1	O60500-1.1	P227F	Pathogenic	0.934
NPHS1	O60500-1.1	P227G	Pathogenic	0.945
NPHS1	O60500-1.1	P227H	Pathogenic	0.911
NPHS1	O60500-1.1	P227I	Pathogenic	0.943
NPHS1	O60500-1.1	P227K	Pathogenic	0.992
NPHS1	O60500-1.1	P227L	Pathogenic	0.934
NPHS1	O60500-1.1	P227M	Pathogenic	0.913
NPHS1	O60500-1.1	P227N	Pathogenic	0.947
NPHS1	O60500-1.1	P227Q	Pathogenic	0.959
NPHS1	O60500-1.1	P227R	Pathogenic	0.991
NPHS1	O60500-1.1	P227S	Pathogenic	0.938
NPHS1	O60500-1.1	P227T	Pathogenic	0.875
NPHS1	O60500-1.1	P227V	Pathogenic	0.868
NPHS1	O60500-1.1	P227W	Pathogenic	0.982
NPHS1	O60500-1.1	P227Y	Pathogenic	0.876
NPHS1	O60500-1.1	I228A	Pathogenic	0.893
NPHS1	O60500-1.1	I228C	Pathogenic	0.661
NPHS1	O60500-1.1	I228D	Pathogenic	0.914
NPHS1	O60500-1.1	I228E	Pathogenic	0.85
NPHS1	O60500-1.1	I228F	Neutral	0.317
NPHS1	O60500-1.1	I228G	Pathogenic	0.862
NPHS1	O60500-1.1	I228H	Pathogenic	0.594
NPHS1	O60500-1.1	I228K	Pathogenic	0.897
NPHS1	O60500-1.1	I228L	Neutral	0.475
NPHS1	O60500-1.1	I228M	Pathogenic	0.55
NPHS1	O60500-1.1	I228N	Pathogenic	0.88
NPHS1	O60500-1.1	I228P	Pathogenic	0.542
NPHS1	O60500-1.1	I228Q	Pathogenic	0.731
NPHS1	O60500-1.1	I228R	Pathogenic	0.924
NPHS1	O60500-1.1	I228S	Pathogenic	0.89
NPHS1	O60500-1.1	I228T	Pathogenic	0.83
NPHS1	O60500-1.1	I228V	Pathogenic	0.813
NPHS1	O60500-1.1	I228W	Neutral	0.34
NPHS1	O60500-1.1	I228Y	Pathogenic	0.551
NPHS1	O60500-1.1	K229A	Pathogenic	0.722
NPHS1	O60500-1.1	K229C	Pathogenic	0.671
NPHS1	O60500-1.1	K229D	Neutral	0.229
NPHS1	O60500-1.1	K229E	Neutral	0.344
NPHS1	O60500-1.1	K229F	Pathogenic	0.68
NPHS1	O60500-1.1	K229G	Pathogenic	0.634
NPHS1	O60500-1.1	K229H	Neutral	0.375
NPHS1	O60500-1.1	K229I	Pathogenic	0.738
NPHS1	O60500-1.1	K229L	Pathogenic	0.783
NPHS1	O60500-1.1	K229M	Pathogenic	0.728
NPHS1	O60500-1.1	K229N	Neutral	0.336
NPHS1	O60500-1.1	K229P	Pathogenic	0.736
NPHS1	O60500-1.1	K229Q	Neutral	0.465
NPHS1	O60500-1.1	K229R	Neutral	0.259
NPHS1	O60500-1.1	K229S	Pathogenic	0.669
NPHS1	O60500-1.1	K229T	Pathogenic	0.566
NPHS1	O60500-1.1	K229V	Pathogenic	0.733
NPHS1	O60500-1.1	K229W	Pathogenic	0.891
NPHS1	O60500-1.1	K229Y	Pathogenic	0.516
NPHS1	O60500-1.1	A230C	Neutral	0.128
NPHS1	O60500-1.1	A230D	Neutral	0.119
NPHS1	O60500-1.1	A230E	Neutral	0.202
NPHS1	O60500-1.1	A230F	Neutral	0.411
NPHS1	O60500-1.1	A230G	Neutral	0.078
NPHS1	O60500-1.1	A230H	Neutral	0.063
NPHS1	O60500-1.1	A230I	Neutral	0.45
NPHS1	O60500-1.1	A230K	Neutral	0.442
NPHS1	O60500-1.1	A230L	Neutral	0.413
NPHS1	O60500-1.1	A230M	Neutral	0.259
NPHS1	O60500-1.1	A230N	Neutral	0.106
NPHS1	O60500-1.1	A230P	Neutral	0.068
NPHS1	O60500-1.1	A230Q	Neutral	0.133
NPHS1	O60500-1.1	A230R	Pathogenic	0.524
NPHS1	O60500-1.1	A230S	Neutral	0.09
NPHS1	O60500-1.1	A230T	Neutral	0.064
NPHS1	O60500-1.1	A230V	Neutral	0.246
NPHS1	O60500-1.1	A230W	Pathogenic	0.643
NPHS1	O60500-1.1	A230Y	Neutral	0.19
NPHS1	O60500-1.1	S231A	Pathogenic	0.536
NPHS1	O60500-1.1	S231C	Pathogenic	0.626
NPHS1	O60500-1.1	S231D	Pathogenic	0.647
NPHS1	O60500-1.1	S231E	Pathogenic	0.697
NPHS1	O60500-1.1	S231F	Pathogenic	0.922
NPHS1	O60500-1.1	S231G	Neutral	0.434
NPHS1	O60500-1.1	S231H	Pathogenic	0.501
NPHS1	O60500-1.1	S231I	Pathogenic	0.903
NPHS1	O60500-1.1	S231K	Pathogenic	0.878
NPHS1	O60500-1.1	S231L	Pathogenic	0.889
NPHS1	O60500-1.1	S231M	Pathogenic	0.856
NPHS1	O60500-1.1	S231N	Pathogenic	0.705
NPHS1	O60500-1.1	S231P	Pathogenic	0.553
NPHS1	O60500-1.1	S231Q	Pathogenic	0.582
NPHS1	O60500-1.1	S231R	Pathogenic	0.87
NPHS1	O60500-1.1	S231T	Pathogenic	0.598
NPHS1	O60500-1.1	S231V	Pathogenic	0.713
NPHS1	O60500-1.1	S231W	Pathogenic	0.968
NPHS1	O60500-1.1	S231Y	Pathogenic	0.799
NPHS1	O60500-1.1	F232A	Pathogenic	0.812
NPHS1	O60500-1.1	F232C	Pathogenic	0.503
NPHS1	O60500-1.1	F232D	Pathogenic	0.891
NPHS1	O60500-1.1	F232E	Pathogenic	0.815
NPHS1	O60500-1.1	F232G	Pathogenic	0.878
NPHS1	O60500-1.1	F232H	Pathogenic	0.715
NPHS1	O60500-1.1	F232I	Neutral	0.22
NPHS1	O60500-1.1	F232K	Pathogenic	0.8
NPHS1	O60500-1.1	F232L	Neutral	0.239
NPHS1	O60500-1.1	F232M	Neutral	0.388
NPHS1	O60500-1.1	F232N	Pathogenic	0.85
NPHS1	O60500-1.1	F232P	Neutral	0.38
NPHS1	O60500-1.1	F232Q	Pathogenic	0.677
NPHS1	O60500-1.1	F232R	Pathogenic	0.848
NPHS1	O60500-1.1	F232S	Pathogenic	0.862
NPHS1	O60500-1.1	F232T	Pathogenic	0.716
NPHS1	O60500-1.1	F232V	Neutral	0.405
NPHS1	O60500-1.1	F232W	Pathogenic	0.55
NPHS1	O60500-1.1	F232Y	Pathogenic	0.736
NPHS1	O60500-1.1	T233A	Pathogenic	0.74
NPHS1	O60500-1.1	T233C	Pathogenic	0.769
NPHS1	O60500-1.1	T233D	Pathogenic	0.822
NPHS1	O60500-1.1	T233E	Pathogenic	0.841
NPHS1	O60500-1.1	T233F	Pathogenic	0.944
NPHS1	O60500-1.1	T233G	Pathogenic	0.731
NPHS1	O60500-1.1	T233H	Pathogenic	0.582
NPHS1	O60500-1.1	T233I	Pathogenic	0.952
NPHS1	O60500-1.1	T233K	Pathogenic	0.943
NPHS1	O60500-1.1	T233L	Pathogenic	0.945
NPHS1	O60500-1.1	T233M	Pathogenic	0.895
NPHS1	O60500-1.1	T233N	Pathogenic	0.846
NPHS1	O60500-1.1	T233P	Pathogenic	0.671
NPHS1	O60500-1.1	T233Q	Pathogenic	0.762
NPHS1	O60500-1.1	T233R	Pathogenic	0.958
NPHS1	O60500-1.1	T233S	Pathogenic	0.841
NPHS1	O60500-1.1	T233V	Pathogenic	0.888
NPHS1	O60500-1.1	T233W	Pathogenic	0.985
NPHS1	O60500-1.1	T233Y	Pathogenic	0.85
NPHS1	O60500-1.1	V234A	Neutral	0.345
NPHS1	O60500-1.1	V234C	Neutral	0.076
NPHS1	O60500-1.1	V234D	Neutral	0.309
NPHS1	O60500-1.1	V234E	Neutral	0.302
NPHS1	O60500-1.1	V234F	Neutral	0.15
NPHS1	O60500-1.1	V234G	Neutral	0.282
NPHS1	O60500-1.1	V234H	Neutral	0.103
NPHS1	O60500-1.1	V234I	Neutral	0.408
NPHS1	O60500-1.1	V234K	Pathogenic	0.575
NPHS1	O60500-1.1	V234L	Neutral	0.21
NPHS1	O60500-1.1	V234M	Neutral	0.117
NPHS1	O60500-1.1	V234N	Neutral	0.236
NPHS1	O60500-1.1	V234P	Neutral	0.069
NPHS1	O60500-1.1	V234Q	Neutral	0.208
NPHS1	O60500-1.1	V234R	Pathogenic	0.558
NPHS1	O60500-1.1	V234S	Neutral	0.256
NPHS1	O60500-1.1	V234T	Neutral	0.235
NPHS1	O60500-1.1	V234W	Neutral	0.235
NPHS1	O60500-1.1	V234Y	Neutral	0.113
NPHS1	O60500-1.1	N235A	Pathogenic	0.98
NPHS1	O60500-1.1	N235C	Pathogenic	0.983
NPHS1	O60500-1.1	N235D	Pathogenic	0.968
NPHS1	O60500-1.1	N235E	Pathogenic	0.953
NPHS1	O60500-1.1	N235F	Pathogenic	0.997
NPHS1	O60500-1.1	N235G	Pathogenic	0.991
NPHS1	O60500-1.1	N235H	Pathogenic	0.991
NPHS1	O60500-1.1	N235I	Pathogenic	0.997
NPHS1	O60500-1.1	N235K	Pathogenic	0.985
NPHS1	O60500-1.1	N235L	Pathogenic	0.996
NPHS1	O60500-1.1	N235M	Pathogenic	0.995
NPHS1	O60500-1.1	N235P	Pathogenic	0.981
NPHS1	O60500-1.1	N235Q	Pathogenic	0.975
NPHS1	O60500-1.1	N235R	Pathogenic	0.989
NPHS1	O60500-1.1	N235S	Pathogenic	0.988
NPHS1	O60500-1.1	N235T	Pathogenic	0.982
NPHS1	O60500-1.1	N235V	Pathogenic	0.988
NPHS1	O60500-1.1	N235W	Pathogenic	0.999
NPHS1	O60500-1.1	N235Y	Pathogenic	0.995
NPHS1	O60500-1.1	V236A	Pathogenic	0.843
NPHS1	O60500-1.1	V236C	Neutral	0.457
NPHS1	O60500-1.1	V236D	Pathogenic	0.82
NPHS1	O60500-1.1	V236E	Pathogenic	0.815
NPHS1	O60500-1.1	V236F	Pathogenic	0.643
NPHS1	O60500-1.1	V236G	Pathogenic	0.8
NPHS1	O60500-1.1	V236H	Pathogenic	0.538
NPHS1	O60500-1.1	V236I	Pathogenic	0.875
NPHS1	O60500-1.1	V236K	Pathogenic	0.932
NPHS1	O60500-1.1	V236L	Pathogenic	0.73
NPHS1	O60500-1.1	V236M	Pathogenic	0.574
NPHS1	O60500-1.1	V236N	Pathogenic	0.759
NPHS1	O60500-1.1	V236P	Neutral	0.432
NPHS1	O60500-1.1	V236Q	Pathogenic	0.727
NPHS1	O60500-1.1	V236R	Pathogenic	0.928
NPHS1	O60500-1.1	V236S	Pathogenic	0.777
NPHS1	O60500-1.1	V236T	Pathogenic	0.758
NPHS1	O60500-1.1	V236W	Pathogenic	0.757
NPHS1	O60500-1.1	V236Y	Pathogenic	0.565
NPHS1	O60500-1.1	L237A	Pathogenic	0.978
NPHS1	O60500-1.1	L237C	Pathogenic	0.913
NPHS1	O60500-1.1	L237D	Pathogenic	0.975
NPHS1	O60500-1.1	L237E	Pathogenic	0.968
NPHS1	O60500-1.1	L237F	Pathogenic	0.764
NPHS1	O60500-1.1	L237G	Pathogenic	0.971
NPHS1	O60500-1.1	L237H	Pathogenic	0.887
NPHS1	O60500-1.1	L237I	Pathogenic	0.85
NPHS1	O60500-1.1	L237K	Pathogenic	0.986
NPHS1	O60500-1.1	L237M	Pathogenic	0.908
NPHS1	O60500-1.1	L237N	Pathogenic	0.975
NPHS1	O60500-1.1	L237P	Pathogenic	0.864
NPHS1	O60500-1.1	L237Q	Pathogenic	0.956
NPHS1	O60500-1.1	L237R	Pathogenic	0.99
NPHS1	O60500-1.1	L237S	Pathogenic	0.978
NPHS1	O60500-1.1	L237T	Pathogenic	0.963
NPHS1	O60500-1.1	L237V	Pathogenic	0.913
NPHS1	O60500-1.1	L237W	Pathogenic	0.849
NPHS1	O60500-1.1	L237Y	Pathogenic	0.869
NPHS1	O60500-1.1	F238A	Pathogenic	0.998
NPHS1	O60500-1.1	F238C	Pathogenic	0.992
NPHS1	O60500-1.1	F238D	Pathogenic	0.999
NPHS1	O60500-1.1	F238E	Pathogenic	0.998
NPHS1	O60500-1.1	F238G	Pathogenic	0.999
NPHS1	O60500-1.1	F238H	Pathogenic	0.997
NPHS1	O60500-1.1	F238I	Pathogenic	0.973
NPHS1	O60500-1.1	F238K	Pathogenic	0.998
NPHS1	O60500-1.1	F238L	Pathogenic	0.976
NPHS1	O60500-1.1	F238M	Pathogenic	0.988
NPHS1	O60500-1.1	F238N	Pathogenic	0.999
NPHS1	O60500-1.1	F238P	Pathogenic	0.987
NPHS1	O60500-1.1	F238Q	Pathogenic	0.996
NPHS1	O60500-1.1	F238R	Pathogenic	0.999
NPHS1	O60500-1.1	F238S	Pathogenic	0.999
NPHS1	O60500-1.1	F238T	Pathogenic	0.997
NPHS1	O60500-1.1	F238V	Pathogenic	0.989
NPHS1	O60500-1.1	F238W	Pathogenic	0.994
NPHS1	O60500-1.1	F238Y	Pathogenic	0.997
NPHS1	O60500-1.1	P239A	Pathogenic	0.972
NPHS1	O60500-1.1	P239C	Pathogenic	0.887
NPHS1	O60500-1.1	P239D	Pathogenic	0.99
NPHS1	O60500-1.1	P239E	Pathogenic	0.992
NPHS1	O60500-1.1	P239F	Pathogenic	0.979
NPHS1	O60500-1.1	P239G	Pathogenic	0.983
NPHS1	O60500-1.1	P239H	Pathogenic	0.971
NPHS1	O60500-1.1	P239I	Pathogenic	0.982
NPHS1	O60500-1.1	P239K	Pathogenic	0.997
NPHS1	O60500-1.1	P239L	Pathogenic	0.979
NPHS1	O60500-1.1	P239M	Pathogenic	0.972
NPHS1	O60500-1.1	P239N	Pathogenic	0.983
NPHS1	O60500-1.1	P239Q	Pathogenic	0.987
NPHS1	O60500-1.1	P239R	Pathogenic	0.997
NPHS1	O60500-1.1	P239S	Pathogenic	0.98
NPHS1	O60500-1.1	P239T	Pathogenic	0.958
NPHS1	O60500-1.1	P239V	Pathogenic	0.956
NPHS1	O60500-1.1	P239W	Pathogenic	0.994
NPHS1	O60500-1.1	P239Y	Pathogenic	0.959
NPHS1	O60500-1.1	P240A	Pathogenic	0.972
NPHS1	O60500-1.1	P240C	Pathogenic	0.887
NPHS1	O60500-1.1	P240D	Pathogenic	0.99
NPHS1	O60500-1.1	P240E	Pathogenic	0.992
NPHS1	O60500-1.1	P240F	Pathogenic	0.979
NPHS1	O60500-1.1	P240G	Pathogenic	0.983
NPHS1	O60500-1.1	P240H	Pathogenic	0.971
NPHS1	O60500-1.1	P240I	Pathogenic	0.982
NPHS1	O60500-1.1	P240K	Pathogenic	0.997
NPHS1	O60500-1.1	P240L	Pathogenic	0.979
NPHS1	O60500-1.1	P240M	Pathogenic	0.972
NPHS1	O60500-1.1	P240N	Pathogenic	0.983
NPHS1	O60500-1.1	P240Q	Pathogenic	0.987
NPHS1	O60500-1.1	P240R	Pathogenic	0.997
NPHS1	O60500-1.1	P240S	Pathogenic	0.98
NPHS1	O60500-1.1	P240T	Pathogenic	0.958
NPHS1	O60500-1.1	P240V	Pathogenic	0.956
NPHS1	O60500-1.1	P240W	Pathogenic	0.994
NPHS1	O60500-1.1	P240Y	Pathogenic	0.959
NPHS1	O60500-1.1	G241A	Neutral	0.254
NPHS1	O60500-1.1	G241C	Neutral	0.305
NPHS1	O60500-1.1	G241D	Neutral	0.444
NPHS1	O60500-1.1	G241E	Neutral	0.402
NPHS1	O60500-1.1	G241F	Pathogenic	0.822
NPHS1	O60500-1.1	G241H	Neutral	0.282
NPHS1	O60500-1.1	G241I	Pathogenic	0.71
NPHS1	O60500-1.1	G241K	Pathogenic	0.678
NPHS1	O60500-1.1	G241L	Pathogenic	0.677
NPHS1	O60500-1.1	G241M	Pathogenic	0.609
NPHS1	O60500-1.1	G241N	Pathogenic	0.511
NPHS1	O60500-1.1	G241P	Neutral	0.326
NPHS1	O60500-1.1	G241Q	Neutral	0.289
NPHS1	O60500-1.1	G241R	Pathogenic	0.745
NPHS1	O60500-1.1	G241S	Neutral	0.207
NPHS1	O60500-1.1	G241T	Neutral	0.207
NPHS1	O60500-1.1	G241V	Neutral	0.493
NPHS1	O60500-1.1	G241W	Pathogenic	0.964
NPHS1	O60500-1.1	G241Y	Pathogenic	0.608
NPHS1	O60500-1.1	P242A	Pathogenic	0.81
NPHS1	O60500-1.1	P242C	Neutral	0.496
NPHS1	O60500-1.1	P242D	Pathogenic	0.927
NPHS1	O60500-1.1	P242E	Pathogenic	0.941
NPHS1	O60500-1.1	P242F	Pathogenic	0.853
NPHS1	O60500-1.1	P242G	Pathogenic	0.876
NPHS1	O60500-1.1	P242H	Pathogenic	0.807
NPHS1	O60500-1.1	P242I	Pathogenic	0.872
NPHS1	O60500-1.1	P242K	Pathogenic	0.98
NPHS1	O60500-1.1	P242L	Pathogenic	0.854
NPHS1	O60500-1.1	P242M	Pathogenic	0.812
NPHS1	O60500-1.1	P242N	Pathogenic	0.881
NPHS1	O60500-1.1	P242Q	Pathogenic	0.906
NPHS1	O60500-1.1	P242R	Pathogenic	0.979
NPHS1	O60500-1.1	P242S	Pathogenic	0.861
NPHS1	O60500-1.1	P242T	Pathogenic	0.742
NPHS1	O60500-1.1	P242V	Pathogenic	0.73
NPHS1	O60500-1.1	P242W	Pathogenic	0.957
NPHS1	O60500-1.1	P242Y	Pathogenic	0.743
NPHS1	O60500-1.1	P243A	Pathogenic	0.978
NPHS1	O60500-1.1	P243C	Pathogenic	0.91
NPHS1	O60500-1.1	P243D	Pathogenic	0.992
NPHS1	O60500-1.1	P243E	Pathogenic	0.994
NPHS1	O60500-1.1	P243F	Pathogenic	0.983
NPHS1	O60500-1.1	P243G	Pathogenic	0.986
NPHS1	O60500-1.1	P243H	Pathogenic	0.977
NPHS1	O60500-1.1	P243I	Pathogenic	0.986
NPHS1	O60500-1.1	P243K	Pathogenic	0.998
NPHS1	O60500-1.1	P243L	Pathogenic	0.983
NPHS1	O60500-1.1	P243M	Pathogenic	0.978
NPHS1	O60500-1.1	P243N	Pathogenic	0.987
NPHS1	O60500-1.1	P243Q	Pathogenic	0.99
NPHS1	O60500-1.1	P243R	Pathogenic	0.998
NPHS1	O60500-1.1	P243S	Pathogenic	0.984
NPHS1	O60500-1.1	P243T	Pathogenic	0.967
NPHS1	O60500-1.1	P243V	Pathogenic	0.965
NPHS1	O60500-1.1	P243W	Pathogenic	0.996
NPHS1	O60500-1.1	P243Y	Pathogenic	0.967
NPHS1	O60500-1.1	V244A	Neutral	0.392
NPHS1	O60500-1.1	V244C	Neutral	0.092
NPHS1	O60500-1.1	V244D	Neutral	0.354
NPHS1	O60500-1.1	V244E	Neutral	0.347
NPHS1	O60500-1.1	V244F	Neutral	0.178
NPHS1	O60500-1.1	V244G	Neutral	0.325
NPHS1	O60500-1.1	V244H	Neutral	0.123
NPHS1	O60500-1.1	V244I	Neutral	0.458
NPHS1	O60500-1.1	V244K	Pathogenic	0.624
NPHS1	O60500-1.1	V244L	Neutral	0.246
NPHS1	O60500-1.1	V244M	Neutral	0.14
NPHS1	O60500-1.1	V244N	Neutral	0.275
NPHS1	O60500-1.1	V244P	Neutral	0.084
NPHS1	O60500-1.1	V244Q	Neutral	0.243
NPHS1	O60500-1.1	V244R	Pathogenic	0.607
NPHS1	O60500-1.1	V244S	Neutral	0.296
NPHS1	O60500-1.1	V244T	Neutral	0.274
NPHS1	O60500-1.1	V244W	Neutral	0.273
NPHS1	O60500-1.1	V244Y	Neutral	0.135
NPHS1	O60500-1.1	I245A	Pathogenic	0.999
NPHS1	O60500-1.1	I245C	Pathogenic	0.998
NPHS1	O60500-1.1	I245D	Pathogenic	1.0
NPHS1	O60500-1.1	I245E	Pathogenic	0.999
NPHS1	O60500-1.1	I245F	Pathogenic	0.99
NPHS1	O60500-1.1	I245G	Pathogenic	0.999
NPHS1	O60500-1.1	I245H	Pathogenic	0.997
NPHS1	O60500-1.1	I245K	Pathogenic	0.999
NPHS1	O60500-1.1	I245L	Pathogenic	0.995
NPHS1	O60500-1.1	I245M	Pathogenic	0.996
NPHS1	O60500-1.1	I245N	Pathogenic	0.999
NPHS1	O60500-1.1	I245P	Pathogenic	0.996
NPHS1	O60500-1.1	I245Q	Pathogenic	0.998
NPHS1	O60500-1.1	I245R	Pathogenic	1.0
NPHS1	O60500-1.1	I245S	Pathogenic	0.999
NPHS1	O60500-1.1	I245T	Pathogenic	0.999
NPHS1	O60500-1.1	I245V	Pathogenic	0.999
NPHS1	O60500-1.1	I245W	Pathogenic	0.991
NPHS1	O60500-1.1	I245Y	Pathogenic	0.996
NPHS1	O60500-1.1	E246A	Pathogenic	0.75
NPHS1	O60500-1.1	E246C	Pathogenic	0.611
NPHS1	O60500-1.1	E246D	Pathogenic	0.627
NPHS1	O60500-1.1	E246F	Pathogenic	0.893
NPHS1	O60500-1.1	E246G	Pathogenic	0.665
NPHS1	O60500-1.1	E246H	Pathogenic	0.612
NPHS1	O60500-1.1	E246I	Pathogenic	0.868
NPHS1	O60500-1.1	E246K	Pathogenic	0.653
NPHS1	O60500-1.1	E246L	Pathogenic	0.85
NPHS1	O60500-1.1	E246M	Pathogenic	0.807
NPHS1	O60500-1.1	E246N	Neutral	0.368
NPHS1	O60500-1.1	E246P	Pathogenic	0.762
NPHS1	O60500-1.1	E246Q	Pathogenic	0.654
NPHS1	O60500-1.1	E246R	Pathogenic	0.637
NPHS1	O60500-1.1	E246S	Pathogenic	0.699
NPHS1	O60500-1.1	E246T	Pathogenic	0.6
NPHS1	O60500-1.1	E246V	Pathogenic	0.76
NPHS1	O60500-1.1	E246W	Pathogenic	0.97
NPHS1	O60500-1.1	E246Y	Pathogenic	0.807
NPHS1	O60500-1.1	W247A	Pathogenic	0.999
NPHS1	O60500-1.1	W247C	Pathogenic	0.998
NPHS1	O60500-1.1	W247D	Pathogenic	1.0
NPHS1	O60500-1.1	W247E	Pathogenic	1.0
NPHS1	O60500-1.1	W247F	Pathogenic	0.994
NPHS1	O60500-1.1	W247G	Pathogenic	1.0
NPHS1	O60500-1.1	W247H	Pathogenic	0.999
NPHS1	O60500-1.1	W247I	Pathogenic	0.979
NPHS1	O60500-1.1	W247K	Pathogenic	1.0
NPHS1	O60500-1.1	W247L	Pathogenic	0.988
NPHS1	O60500-1.1	W247M	Pathogenic	0.996
NPHS1	O60500-1.1	W247N	Pathogenic	1.0
NPHS1	O60500-1.1	W247P	Pathogenic	0.997
NPHS1	O60500-1.1	W247Q	Pathogenic	0.999
NPHS1	O60500-1.1	W247R	Pathogenic	0.999
NPHS1	O60500-1.1	W247S	Pathogenic	1.0
NPHS1	O60500-1.1	W247T	Pathogenic	0.999
NPHS1	O60500-1.1	W247V	Pathogenic	0.994
NPHS1	O60500-1.1	W247Y	Pathogenic	0.999
NPHS1	O60500-1.1	P248A	Pathogenic	0.727
NPHS1	O60500-1.1	P248C	Neutral	0.38
NPHS1	O60500-1.1	P248D	Pathogenic	0.887
NPHS1	O60500-1.1	P248E	Pathogenic	0.908
NPHS1	O60500-1.1	P248F	Pathogenic	0.782
NPHS1	O60500-1.1	P248G	Pathogenic	0.815
NPHS1	O60500-1.1	P248H	Pathogenic	0.723
NPHS1	O60500-1.1	P248I	Pathogenic	0.809
NPHS1	O60500-1.1	P248K	Pathogenic	0.969
NPHS1	O60500-1.1	P248L	Pathogenic	0.784
NPHS1	O60500-1.1	P248M	Pathogenic	0.729
NPHS1	O60500-1.1	P248N	Pathogenic	0.822
NPHS1	O60500-1.1	P248Q	Pathogenic	0.857
NPHS1	O60500-1.1	P248R	Pathogenic	0.966
NPHS1	O60500-1.1	P248S	Pathogenic	0.794
NPHS1	O60500-1.1	P248T	Pathogenic	0.641
NPHS1	O60500-1.1	P248V	Pathogenic	0.627
NPHS1	O60500-1.1	P248W	Pathogenic	0.933
NPHS1	O60500-1.1	P248Y	Pathogenic	0.643
NPHS1	O60500-1.1	G249A	Pathogenic	0.974
NPHS1	O60500-1.1	G249C	Pathogenic	0.98
NPHS1	O60500-1.1	G249D	Pathogenic	0.989
NPHS1	O60500-1.1	G249E	Pathogenic	0.987
NPHS1	O60500-1.1	G249F	Pathogenic	0.998
NPHS1	O60500-1.1	G249H	Pathogenic	0.978
NPHS1	O60500-1.1	G249I	Pathogenic	0.996
NPHS1	O60500-1.1	G249K	Pathogenic	0.996
NPHS1	O60500-1.1	G249L	Pathogenic	0.996
NPHS1	O60500-1.1	G249M	Pathogenic	0.994
NPHS1	O60500-1.1	G249N	Pathogenic	0.992
NPHS1	O60500-1.1	G249P	Pathogenic	0.982
NPHS1	O60500-1.1	G249Q	Pathogenic	0.979
NPHS1	O60500-1.1	G249R	Pathogenic	0.997
NPHS1	O60500-1.1	G249S	Pathogenic	0.967
NPHS1	O60500-1.1	G249T	Pathogenic	0.967
NPHS1	O60500-1.1	G249V	Pathogenic	0.991
NPHS1	O60500-1.1	G249W	Pathogenic	1.0
NPHS1	O60500-1.1	G249Y	Pathogenic	0.994
NPHS1	O60500-1.1	L250A	Pathogenic	0.846
NPHS1	O60500-1.1	L250C	Pathogenic	0.563
NPHS1	O60500-1.1	L250D	Pathogenic	0.824
NPHS1	O60500-1.1	L250E	Pathogenic	0.789
NPHS1	O60500-1.1	L250F	Neutral	0.284
NPHS1	O60500-1.1	L250G	Pathogenic	0.804
NPHS1	O60500-1.1	L250H	Neutral	0.491
NPHS1	O60500-1.1	L250I	Neutral	0.41
NPHS1	O60500-1.1	L250K	Pathogenic	0.896
NPHS1	O60500-1.1	L250M	Pathogenic	0.545
NPHS1	O60500-1.1	L250N	Pathogenic	0.828
NPHS1	O60500-1.1	L250P	Neutral	0.438
NPHS1	O60500-1.1	L250Q	Pathogenic	0.727
NPHS1	O60500-1.1	L250R	Pathogenic	0.923
NPHS1	O60500-1.1	L250S	Pathogenic	0.842
NPHS1	O60500-1.1	L250T	Pathogenic	0.763
NPHS1	O60500-1.1	L250V	Pathogenic	0.563
NPHS1	O60500-1.1	L250W	Neutral	0.407
NPHS1	O60500-1.1	L250Y	Neutral	0.447
NPHS1	O60500-1.1	D251A	Neutral	0.081
NPHS1	O60500-1.1	D251C	Neutral	0.093
NPHS1	O60500-1.1	D251E	Neutral	0.085
NPHS1	O60500-1.1	D251F	Neutral	0.462
NPHS1	O60500-1.1	D251G	Neutral	0.115
NPHS1	O60500-1.1	D251H	Neutral	0.098
NPHS1	O60500-1.1	D251I	Neutral	0.404
NPHS1	O60500-1.1	D251K	Neutral	0.056
NPHS1	O60500-1.1	D251L	Neutral	0.281
NPHS1	O60500-1.1	D251M	Neutral	0.224
NPHS1	O60500-1.1	D251N	Neutral	0.046
NPHS1	O60500-1.1	D251P	Neutral	0.123
NPHS1	O60500-1.1	D251Q	Neutral	0.08
NPHS1	O60500-1.1	D251R	Neutral	0.052
NPHS1	O60500-1.1	D251S	Neutral	0.093
NPHS1	O60500-1.1	D251T	Neutral	0.068
NPHS1	O60500-1.1	D251V	Neutral	0.153
NPHS1	O60500-1.1	D251W	Pathogenic	0.69
NPHS1	O60500-1.1	D251Y	Neutral	0.224
NPHS1	O60500-1.1	E252A	Neutral	0.33
NPHS1	O60500-1.1	E252C	Neutral	0.206
NPHS1	O60500-1.1	E252D	Neutral	0.216
NPHS1	O60500-1.1	E252F	Pathogenic	0.579
NPHS1	O60500-1.1	E252G	Neutral	0.247
NPHS1	O60500-1.1	E252H	Neutral	0.206
NPHS1	O60500-1.1	E252I	Pathogenic	0.52
NPHS1	O60500-1.1	E252K	Neutral	0.237
NPHS1	O60500-1.1	E252L	Neutral	0.482
NPHS1	O60500-1.1	E252M	Neutral	0.408
NPHS1	O60500-1.1	E252N	Neutral	0.087
NPHS1	O60500-1.1	E252P	Neutral	0.345
NPHS1	O60500-1.1	E252Q	Neutral	0.237
NPHS1	O60500-1.1	E252R	Neutral	0.224
NPHS1	O60500-1.1	E252S	Neutral	0.276
NPHS1	O60500-1.1	E252T	Neutral	0.198
NPHS1	O60500-1.1	E252V	Neutral	0.343
NPHS1	O60500-1.1	E252W	Pathogenic	0.841
NPHS1	O60500-1.1	E252Y	Neutral	0.408
NPHS1	O60500-1.1	G253A	Neutral	0.09
NPHS1	O60500-1.1	G253C	Neutral	0.113
NPHS1	O60500-1.1	G253D	Neutral	0.189
NPHS1	O60500-1.1	G253E	Neutral	0.164
NPHS1	O60500-1.1	G253F	Pathogenic	0.574
NPHS1	O60500-1.1	G253H	Neutral	0.102
NPHS1	O60500-1.1	G253I	Neutral	0.416
NPHS1	O60500-1.1	G253K	Neutral	0.379
NPHS1	O60500-1.1	G253L	Neutral	0.379
NPHS1	O60500-1.1	G253M	Neutral	0.312
NPHS1	O60500-1.1	G253N	Neutral	0.233
NPHS1	O60500-1.1	G253P	Neutral	0.124
NPHS1	O60500-1.1	G253Q	Neutral	0.106
NPHS1	O60500-1.1	G253R	Neutral	0.459
NPHS1	O60500-1.1	G253S	Neutral	0.071
NPHS1	O60500-1.1	G253T	Neutral	0.071
NPHS1	O60500-1.1	G253V	Neutral	0.221
NPHS1	O60500-1.1	G253W	Pathogenic	0.886
NPHS1	O60500-1.1	G253Y	Neutral	0.311
NPHS1	O60500-1.1	H254A	Neutral	0.148
NPHS1	O60500-1.1	H254C	Neutral	0.169
NPHS1	O60500-1.1	H254D	Neutral	0.303
NPHS1	O60500-1.1	H254E	Neutral	0.258
NPHS1	O60500-1.1	H254F	Pathogenic	0.513
NPHS1	O60500-1.1	H254G	Neutral	0.204
NPHS1	O60500-1.1	H254I	Neutral	0.272
NPHS1	O60500-1.1	H254K	Neutral	0.322
NPHS1	O60500-1.1	H254L	Neutral	0.243
NPHS1	O60500-1.1	H254M	Neutral	0.192
NPHS1	O60500-1.1	H254N	Neutral	0.4
NPHS1	O60500-1.1	H254P	Neutral	0.157
NPHS1	O60500-1.1	H254Q	Neutral	0.142
NPHS1	O60500-1.1	H254R	Neutral	0.497
NPHS1	O60500-1.1	H254S	Neutral	0.183
NPHS1	O60500-1.1	H254T	Neutral	0.08
NPHS1	O60500-1.1	H254V	Neutral	0.156
NPHS1	O60500-1.1	H254W	Pathogenic	0.732
NPHS1	O60500-1.1	H254Y	Pathogenic	0.54
NPHS1	O60500-1.1	V255A	Pathogenic	0.945
NPHS1	O60500-1.1	V255C	Pathogenic	0.728
NPHS1	O60500-1.1	V255D	Pathogenic	0.935
NPHS1	O60500-1.1	V255E	Pathogenic	0.933
NPHS1	O60500-1.1	V255F	Pathogenic	0.851
NPHS1	O60500-1.1	V255G	Pathogenic	0.927
NPHS1	O60500-1.1	V255H	Pathogenic	0.787
NPHS1	O60500-1.1	V255I	Pathogenic	0.957
NPHS1	O60500-1.1	V255K	Pathogenic	0.978
NPHS1	O60500-1.1	V255L	Pathogenic	0.896
NPHS1	O60500-1.1	V255M	Pathogenic	0.811
NPHS1	O60500-1.1	V255N	Pathogenic	0.909
NPHS1	O60500-1.1	V255P	Pathogenic	0.707
NPHS1	O60500-1.1	V255Q	Pathogenic	0.894
NPHS1	O60500-1.1	V255R	Pathogenic	0.976
NPHS1	O60500-1.1	V255S	Pathogenic	0.917
NPHS1	O60500-1.1	V255T	Pathogenic	0.909
NPHS1	O60500-1.1	V255W	Pathogenic	0.908
NPHS1	O60500-1.1	V255Y	Pathogenic	0.805
NPHS1	O60500-1.1	R256A	Pathogenic	0.946
NPHS1	O60500-1.1	R256C	Pathogenic	0.933
NPHS1	O60500-1.1	R256D	Pathogenic	0.575
NPHS1	O60500-1.1	R256E	Pathogenic	0.705
NPHS1	O60500-1.1	R256F	Pathogenic	0.935
NPHS1	O60500-1.1	R256G	Pathogenic	0.921
NPHS1	O60500-1.1	R256H	Pathogenic	0.859
NPHS1	O60500-1.1	R256I	Pathogenic	0.95
NPHS1	O60500-1.1	R256K	Pathogenic	0.63
NPHS1	O60500-1.1	R256L	Pathogenic	0.961
NPHS1	O60500-1.1	R256M	Pathogenic	0.948
NPHS1	O60500-1.1	R256N	Pathogenic	0.774
NPHS1	O60500-1.1	R256P	Pathogenic	0.927
NPHS1	O60500-1.1	R256Q	Pathogenic	0.855
NPHS1	O60500-1.1	R256S	Pathogenic	0.902
NPHS1	O60500-1.1	R256T	Pathogenic	0.898
NPHS1	O60500-1.1	R256V	Pathogenic	0.926
NPHS1	O60500-1.1	R256W	Pathogenic	0.968
NPHS1	O60500-1.1	R256Y	Pathogenic	0.845
NPHS1	O60500-1.1	A257C	Pathogenic	0.855
NPHS1	O60500-1.1	A257D	Pathogenic	0.845
NPHS1	O60500-1.1	A257E	Pathogenic	0.911
NPHS1	O60500-1.1	A257F	Pathogenic	0.966
NPHS1	O60500-1.1	A257G	Pathogenic	0.774
NPHS1	O60500-1.1	A257H	Pathogenic	0.729
NPHS1	O60500-1.1	A257I	Pathogenic	0.971
NPHS1	O60500-1.1	A257K	Pathogenic	0.97
NPHS1	O60500-1.1	A257L	Pathogenic	0.966
NPHS1	O60500-1.1	A257M	Pathogenic	0.934
NPHS1	O60500-1.1	A257N	Pathogenic	0.827
NPHS1	O60500-1.1	A257P	Pathogenic	0.746
NPHS1	O60500-1.1	A257Q	Pathogenic	0.861
NPHS1	O60500-1.1	A257R	Pathogenic	0.978
NPHS1	O60500-1.1	A257S	Pathogenic	0.799
NPHS1	O60500-1.1	A257T	Pathogenic	0.734
NPHS1	O60500-1.1	A257V	Pathogenic	0.929
NPHS1	O60500-1.1	A257W	Pathogenic	0.986
NPHS1	O60500-1.1	A257Y	Pathogenic	0.904
NPHS1	O60500-1.1	G258A	Pathogenic	0.98
NPHS1	O60500-1.1	G258C	Pathogenic	0.984
NPHS1	O60500-1.1	G258D	Pathogenic	0.991
NPHS1	O60500-1.1	G258E	Pathogenic	0.99
NPHS1	O60500-1.1	G258F	Pathogenic	0.998
NPHS1	O60500-1.1	G258H	Pathogenic	0.982
NPHS1	O60500-1.1	G258I	Pathogenic	0.997
NPHS1	O60500-1.1	G258K	Pathogenic	0.997
NPHS1	O60500-1.1	G258L	Pathogenic	0.997
NPHS1	O60500-1.1	G258M	Pathogenic	0.996
NPHS1	O60500-1.1	G258N	Pathogenic	0.993
NPHS1	O60500-1.1	G258P	Pathogenic	0.986
NPHS1	O60500-1.1	G258Q	Pathogenic	0.983
NPHS1	O60500-1.1	G258R	Pathogenic	0.998
NPHS1	O60500-1.1	G258S	Pathogenic	0.974
NPHS1	O60500-1.1	G258T	Pathogenic	0.974
NPHS1	O60500-1.1	G258V	Pathogenic	0.993
NPHS1	O60500-1.1	G258W	Pathogenic	1.0
NPHS1	O60500-1.1	G258Y	Pathogenic	0.996
NPHS1	O60500-1.1	Q259A	Neutral	0.42
NPHS1	O60500-1.1	Q259C	Neutral	0.362
NPHS1	O60500-1.1	Q259D	Neutral	0.387
NPHS1	O60500-1.1	Q259E	Neutral	0.43
NPHS1	O60500-1.1	Q259F	Pathogenic	0.615
NPHS1	O60500-1.1	Q259G	Neutral	0.325
NPHS1	O60500-1.1	Q259H	Neutral	0.231
NPHS1	O60500-1.1	Q259I	Pathogenic	0.557
NPHS1	O60500-1.1	Q259K	Pathogenic	0.555
NPHS1	O60500-1.1	Q259L	Pathogenic	0.617
NPHS1	O60500-1.1	Q259M	Pathogenic	0.64
NPHS1	O60500-1.1	Q259N	Neutral	0.304
NPHS1	O60500-1.1	Q259P	Neutral	0.436
NPHS1	O60500-1.1	Q259R	Pathogenic	0.634
NPHS1	O60500-1.1	Q259S	Neutral	0.359
NPHS1	O60500-1.1	Q259T	Neutral	0.266
NPHS1	O60500-1.1	Q259V	Neutral	0.433
NPHS1	O60500-1.1	Q259W	Pathogenic	0.902
NPHS1	O60500-1.1	Q259Y	Pathogenic	0.544
NPHS1	O60500-1.1	S260A	Neutral	0.021
NPHS1	O60500-1.1	S260C	Neutral	0.03
NPHS1	O60500-1.1	S260D	Neutral	0.032
NPHS1	O60500-1.1	S260E	Neutral	0.04
NPHS1	O60500-1.1	S260F	Neutral	0.177
NPHS1	O60500-1.1	S260G	Neutral	0.014
NPHS1	O60500-1.1	S260H	Neutral	0.018
NPHS1	O60500-1.1	S260I	Neutral	0.145
NPHS1	O60500-1.1	S260K	Neutral	0.116
NPHS1	O60500-1.1	S260L	Neutral	0.127
NPHS1	O60500-1.1	S260M	Neutral	0.098
NPHS1	O60500-1.1	S260N	Neutral	0.042
NPHS1	O60500-1.1	S260P	Neutral	0.022
NPHS1	O60500-1.1	S260Q	Neutral	0.025
NPHS1	O60500-1.1	S260R	Neutral	0.109
NPHS1	O60500-1.1	S260T	Neutral	0.026
NPHS1	O60500-1.1	S260V	Neutral	0.043
NPHS1	O60500-1.1	S260W	Neutral	0.358
NPHS1	O60500-1.1	S260Y	Neutral	0.068
NPHS1	O60500-1.1	L261A	Pathogenic	0.996
NPHS1	O60500-1.1	L261C	Pathogenic	0.982
NPHS1	O60500-1.1	L261D	Pathogenic	0.995
NPHS1	O60500-1.1	L261E	Pathogenic	0.994
NPHS1	O60500-1.1	L261F	Pathogenic	0.943
NPHS1	O60500-1.1	L261G	Pathogenic	0.994
NPHS1	O60500-1.1	L261H	Pathogenic	0.976
NPHS1	O60500-1.1	L261I	Pathogenic	0.967
NPHS1	O60500-1.1	L261K	Pathogenic	0.997
NPHS1	O60500-1.1	L261M	Pathogenic	0.98
NPHS1	O60500-1.1	L261N	Pathogenic	0.995
NPHS1	O60500-1.1	L261P	Pathogenic	0.97
NPHS1	O60500-1.1	L261Q	Pathogenic	0.991
NPHS1	O60500-1.1	L261R	Pathogenic	0.998
NPHS1	O60500-1.1	L261S	Pathogenic	0.996
NPHS1	O60500-1.1	L261T	Pathogenic	0.993
NPHS1	O60500-1.1	L261V	Pathogenic	0.982
NPHS1	O60500-1.1	L261W	Pathogenic	0.966
NPHS1	O60500-1.1	L261Y	Pathogenic	0.971
NPHS1	O60500-1.1	E262A	Pathogenic	0.59
NPHS1	O60500-1.1	E262C	Neutral	0.431
NPHS1	O60500-1.1	E262D	Neutral	0.447
NPHS1	O60500-1.1	E262F	Pathogenic	0.801
NPHS1	O60500-1.1	E262G	Neutral	0.489
NPHS1	O60500-1.1	E262H	Neutral	0.431
NPHS1	O60500-1.1	E262I	Pathogenic	0.76
NPHS1	O60500-1.1	E262K	Neutral	0.476
NPHS1	O60500-1.1	E262L	Pathogenic	0.731
NPHS1	O60500-1.1	E262M	Pathogenic	0.669
NPHS1	O60500-1.1	E262N	Neutral	0.219
NPHS1	O60500-1.1	E262P	Pathogenic	0.606
NPHS1	O60500-1.1	E262Q	Neutral	0.476
NPHS1	O60500-1.1	E262R	Neutral	0.458
NPHS1	O60500-1.1	E262S	Pathogenic	0.527
NPHS1	O60500-1.1	E262T	Neutral	0.419
NPHS1	O60500-1.1	E262V	Pathogenic	0.603
NPHS1	O60500-1.1	E262W	Pathogenic	0.939
NPHS1	O60500-1.1	E262Y	Pathogenic	0.668
NPHS1	O60500-1.1	L263A	Pathogenic	0.996
NPHS1	O60500-1.1	L263C	Pathogenic	0.982
NPHS1	O60500-1.1	L263D	Pathogenic	0.995
NPHS1	O60500-1.1	L263E	Pathogenic	0.994
NPHS1	O60500-1.1	L263F	Pathogenic	0.943
NPHS1	O60500-1.1	L263G	Pathogenic	0.994
NPHS1	O60500-1.1	L263H	Pathogenic	0.976
NPHS1	O60500-1.1	L263I	Pathogenic	0.967
NPHS1	O60500-1.1	L263K	Pathogenic	0.997
NPHS1	O60500-1.1	L263M	Pathogenic	0.98
NPHS1	O60500-1.1	L263N	Pathogenic	0.995
NPHS1	O60500-1.1	L263P	Pathogenic	0.97
NPHS1	O60500-1.1	L263Q	Pathogenic	0.991
NPHS1	O60500-1.1	L263R	Pathogenic	0.998
NPHS1	O60500-1.1	L263S	Pathogenic	0.996
NPHS1	O60500-1.1	L263T	Pathogenic	0.993
NPHS1	O60500-1.1	L263V	Pathogenic	0.982
NPHS1	O60500-1.1	L263W	Pathogenic	0.966
NPHS1	O60500-1.1	L263Y	Pathogenic	0.971
NPHS1	O60500-1.1	P264A	Neutral	0.005
NPHS1	O60500-1.1	P264C	Neutral	0.001
NPHS1	O60500-1.1	P264D	Neutral	0.013
NPHS1	O60500-1.1	P264E	Neutral	0.017
NPHS1	O60500-1.1	P264F	Neutral	0.006
NPHS1	O60500-1.1	P264G	Neutral	0.008
NPHS1	O60500-1.1	P264H	Neutral	0.004
NPHS1	O60500-1.1	P264I	Neutral	0.007
NPHS1	O60500-1.1	P264K	Neutral	0.05
NPHS1	O60500-1.1	P264L	Neutral	0.006
NPHS1	O60500-1.1	P264M	Neutral	0.005
NPHS1	O60500-1.1	P264N	Neutral	0.008
NPHS1	O60500-1.1	P264Q	Neutral	0.01
NPHS1	O60500-1.1	P264R	Neutral	0.047
NPHS1	O60500-1.1	P264S	Neutral	0.007
NPHS1	O60500-1.1	P264T	Neutral	0.003
NPHS1	O60500-1.1	P264V	Neutral	0.003
NPHS1	O60500-1.1	P264W	Neutral	0.023
NPHS1	O60500-1.1	P264Y	Neutral	0.003
NPHS1	O60500-1.1	C265A	Pathogenic	0.98
NPHS1	O60500-1.1	C265D	Pathogenic	0.981
NPHS1	O60500-1.1	C265E	Pathogenic	0.978
NPHS1	O60500-1.1	C265F	Pathogenic	0.982
NPHS1	O60500-1.1	C265G	Pathogenic	0.973
NPHS1	O60500-1.1	C265H	Pathogenic	0.963
NPHS1	O60500-1.1	C265I	Pathogenic	0.984
NPHS1	O60500-1.1	C265K	Pathogenic	0.995
NPHS1	O60500-1.1	C265L	Pathogenic	0.982
NPHS1	O60500-1.1	C265M	Pathogenic	0.964
NPHS1	O60500-1.1	C265N	Pathogenic	0.979
NPHS1	O60500-1.1	C265P	Pathogenic	0.848
NPHS1	O60500-1.1	C265Q	Pathogenic	0.975
NPHS1	O60500-1.1	C265R	Pathogenic	0.997
NPHS1	O60500-1.1	C265S	Pathogenic	0.979
NPHS1	O60500-1.1	C265T	Pathogenic	0.964
NPHS1	O60500-1.1	C265V	Pathogenic	0.944
NPHS1	O60500-1.1	C265W	Pathogenic	0.995
NPHS1	O60500-1.1	C265Y	Pathogenic	0.951
NPHS1	O60500-1.1	V266A	Neutral	0.088
NPHS1	O60500-1.1	V266C	Neutral	0.015
NPHS1	O60500-1.1	V266D	Neutral	0.076
NPHS1	O60500-1.1	V266E	Neutral	0.074
NPHS1	O60500-1.1	V266F	Neutral	0.031
NPHS1	O60500-1.1	V266G	Neutral	0.067
NPHS1	O60500-1.1	V266H	Neutral	0.021
NPHS1	O60500-1.1	V266I	Neutral	0.112
NPHS1	O60500-1.1	V266K	Neutral	0.199
NPHS1	O60500-1.1	V266L	Neutral	0.047
NPHS1	O60500-1.1	V266M	Neutral	0.024
NPHS1	O60500-1.1	V266N	Neutral	0.054
NPHS1	O60500-1.1	V266P	Neutral	0.014
NPHS1	O60500-1.1	V266Q	Neutral	0.046
NPHS1	O60500-1.1	V266R	Neutral	0.188
NPHS1	O60500-1.1	V266S	Neutral	0.059
NPHS1	O60500-1.1	V266T	Neutral	0.053
NPHS1	O60500-1.1	V266W	Neutral	0.053
NPHS1	O60500-1.1	V266Y	Neutral	0.023
NPHS1	O60500-1.1	A267C	Neutral	0.471
NPHS1	O60500-1.1	A267D	Neutral	0.451
NPHS1	O60500-1.1	A267E	Pathogenic	0.606
NPHS1	O60500-1.1	A267F	Pathogenic	0.809
NPHS1	O60500-1.1	A267G	Neutral	0.34
NPHS1	O60500-1.1	A267H	Neutral	0.289
NPHS1	O60500-1.1	A267I	Pathogenic	0.833
NPHS1	O60500-1.1	A267K	Pathogenic	0.828
NPHS1	O60500-1.1	A267L	Pathogenic	0.81
NPHS1	O60500-1.1	A267M	Pathogenic	0.68
NPHS1	O60500-1.1	A267N	Neutral	0.418
NPHS1	O60500-1.1	A267P	Neutral	0.307
NPHS1	O60500-1.1	A267Q	Neutral	0.482
NPHS1	O60500-1.1	A267R	Pathogenic	0.87
NPHS1	O60500-1.1	A267S	Neutral	0.374
NPHS1	O60500-1.1	A267T	Neutral	0.294
NPHS1	O60500-1.1	A267V	Pathogenic	0.664
NPHS1	O60500-1.1	A267W	Pathogenic	0.916
NPHS1	O60500-1.1	A267Y	Pathogenic	0.587
NPHS1	O60500-1.1	R268A	Pathogenic	0.52
NPHS1	O60500-1.1	R268C	Neutral	0.459
NPHS1	O60500-1.1	R268D	Neutral	0.077
NPHS1	O60500-1.1	R268E	Neutral	0.128
NPHS1	O60500-1.1	R268F	Neutral	0.47
NPHS1	O60500-1.1	R268G	Neutral	0.419
NPHS1	O60500-1.1	R268H	Neutral	0.272
NPHS1	O60500-1.1	R268I	Pathogenic	0.54
NPHS1	O60500-1.1	R268K	Neutral	0.095
NPHS1	O60500-1.1	R268L	Pathogenic	0.6
NPHS1	O60500-1.1	R268M	Pathogenic	0.527
NPHS1	O60500-1.1	R268N	Neutral	0.174
NPHS1	O60500-1.1	R268P	Neutral	0.437
NPHS1	O60500-1.1	R268Q	Neutral	0.266
NPHS1	O60500-1.1	R268S	Neutral	0.36
NPHS1	O60500-1.1	R268T	Neutral	0.352
NPHS1	O60500-1.1	R268V	Neutral	0.434
NPHS1	O60500-1.1	R268W	Pathogenic	0.649
NPHS1	O60500-1.1	R268Y	Neutral	0.25
NPHS1	O60500-1.1	G269A	Pathogenic	0.711
NPHS1	O60500-1.1	G269C	Pathogenic	0.76
NPHS1	O60500-1.1	G269D	Pathogenic	0.853
NPHS1	O60500-1.1	G269E	Pathogenic	0.83
NPHS1	O60500-1.1	G269F	Pathogenic	0.971
NPHS1	O60500-1.1	G269H	Pathogenic	0.74
NPHS1	O60500-1.1	G269I	Pathogenic	0.947
NPHS1	O60500-1.1	G269K	Pathogenic	0.938
NPHS1	O60500-1.1	G269L	Pathogenic	0.938
NPHS1	O60500-1.1	G269M	Pathogenic	0.919
NPHS1	O60500-1.1	G269N	Pathogenic	0.883
NPHS1	O60500-1.1	G269P	Pathogenic	0.778
NPHS1	O60500-1.1	G269Q	Pathogenic	0.747
NPHS1	O60500-1.1	G269R	Pathogenic	0.955
NPHS1	O60500-1.1	G269S	Pathogenic	0.654
NPHS1	O60500-1.1	G269T	Pathogenic	0.654
NPHS1	O60500-1.1	G269V	Pathogenic	0.876
NPHS1	O60500-1.1	G269W	Pathogenic	0.995
NPHS1	O60500-1.1	G269Y	Pathogenic	0.918
NPHS1	O60500-1.1	G270A	Pathogenic	0.98
NPHS1	O60500-1.1	G270C	Pathogenic	0.984
NPHS1	O60500-1.1	G270D	Pathogenic	0.991
NPHS1	O60500-1.1	G270E	Pathogenic	0.99
NPHS1	O60500-1.1	G270F	Pathogenic	0.998
NPHS1	O60500-1.1	G270H	Pathogenic	0.982
NPHS1	O60500-1.1	G270I	Pathogenic	0.997
NPHS1	O60500-1.1	G270K	Pathogenic	0.997
NPHS1	O60500-1.1	G270L	Pathogenic	0.997
NPHS1	O60500-1.1	G270M	Pathogenic	0.996
NPHS1	O60500-1.1	G270N	Pathogenic	0.993
NPHS1	O60500-1.1	G270P	Pathogenic	0.986
NPHS1	O60500-1.1	G270Q	Pathogenic	0.983
NPHS1	O60500-1.1	G270R	Pathogenic	0.998
NPHS1	O60500-1.1	G270S	Pathogenic	0.974
NPHS1	O60500-1.1	G270T	Pathogenic	0.974
NPHS1	O60500-1.1	G270V	Pathogenic	0.993
NPHS1	O60500-1.1	G270W	Pathogenic	1.0
NPHS1	O60500-1.1	G270Y	Pathogenic	0.996
NPHS1	O60500-1.1	N271A	Pathogenic	0.997
NPHS1	O60500-1.1	N271C	Pathogenic	0.998
NPHS1	O60500-1.1	N271D	Pathogenic	0.996
NPHS1	O60500-1.1	N271E	Pathogenic	0.994
NPHS1	O60500-1.1	N271F	Pathogenic	1.0
NPHS1	O60500-1.1	N271G	Pathogenic	0.999
NPHS1	O60500-1.1	N271H	Pathogenic	0.999
NPHS1	O60500-1.1	N271I	Pathogenic	1.0
NPHS1	O60500-1.1	N271K	Pathogenic	0.998
NPHS1	O60500-1.1	N271L	Pathogenic	1.0
NPHS1	O60500-1.1	N271M	Pathogenic	0.999
NPHS1	O60500-1.1	N271P	Pathogenic	0.998
NPHS1	O60500-1.1	N271Q	Pathogenic	0.997
NPHS1	O60500-1.1	N271R	Pathogenic	0.999
NPHS1	O60500-1.1	N271S	Pathogenic	0.998
NPHS1	O60500-1.1	N271T	Pathogenic	0.998
NPHS1	O60500-1.1	N271V	Pathogenic	0.998
NPHS1	O60500-1.1	N271W	Pathogenic	1.0
NPHS1	O60500-1.1	N271Y	Pathogenic	0.999
NPHS1	O60500-1.1	P272A	Pathogenic	0.969
NPHS1	O60500-1.1	P272C	Pathogenic	0.88
NPHS1	O60500-1.1	P272D	Pathogenic	0.989
NPHS1	O60500-1.1	P272E	Pathogenic	0.992
NPHS1	O60500-1.1	P272F	Pathogenic	0.977
NPHS1	O60500-1.1	P272G	Pathogenic	0.981
NPHS1	O60500-1.1	P272H	Pathogenic	0.969
NPHS1	O60500-1.1	P272I	Pathogenic	0.981
NPHS1	O60500-1.1	P272K	Pathogenic	0.997
NPHS1	O60500-1.1	P272L	Pathogenic	0.977
NPHS1	O60500-1.1	P272M	Pathogenic	0.97
NPHS1	O60500-1.1	P272N	Pathogenic	0.982
NPHS1	O60500-1.1	P272Q	Pathogenic	0.986
NPHS1	O60500-1.1	P272R	Pathogenic	0.997
NPHS1	O60500-1.1	P272S	Pathogenic	0.979
NPHS1	O60500-1.1	P272T	Pathogenic	0.955
NPHS1	O60500-1.1	P272V	Pathogenic	0.952
NPHS1	O60500-1.1	P272W	Pathogenic	0.994
NPHS1	O60500-1.1	P272Y	Pathogenic	0.955
NPHS1	O60500-1.1	L273A	Pathogenic	0.74
NPHS1	O60500-1.1	L273C	Neutral	0.399
NPHS1	O60500-1.1	L273D	Pathogenic	0.707
NPHS1	O60500-1.1	L273E	Pathogenic	0.659
NPHS1	O60500-1.1	L273F	Neutral	0.17
NPHS1	O60500-1.1	L273G	Pathogenic	0.68
NPHS1	O60500-1.1	L273H	Neutral	0.332
NPHS1	O60500-1.1	L273I	Neutral	0.264
NPHS1	O60500-1.1	L273K	Pathogenic	0.816
NPHS1	O60500-1.1	L273M	Neutral	0.383
NPHS1	O60500-1.1	L273N	Pathogenic	0.713
NPHS1	O60500-1.1	L273P	Neutral	0.287
NPHS1	O60500-1.1	L273Q	Pathogenic	0.579
NPHS1	O60500-1.1	L273R	Pathogenic	0.86
NPHS1	O60500-1.1	L273S	Pathogenic	0.734
NPHS1	O60500-1.1	L273T	Pathogenic	0.624
NPHS1	O60500-1.1	L273V	Neutral	0.4
NPHS1	O60500-1.1	L273W	Neutral	0.262
NPHS1	O60500-1.1	L273Y	Neutral	0.295
NPHS1	O60500-1.1	A274C	Pathogenic	0.969
NPHS1	O60500-1.1	A274D	Pathogenic	0.966
NPHS1	O60500-1.1	A274E	Pathogenic	0.982
NPHS1	O60500-1.1	A274F	Pathogenic	0.993
NPHS1	O60500-1.1	A274G	Pathogenic	0.947
NPHS1	O60500-1.1	A274H	Pathogenic	0.934
NPHS1	O60500-1.1	A274I	Pathogenic	0.994
NPHS1	O60500-1.1	A274K	Pathogenic	0.994
NPHS1	O60500-1.1	A274L	Pathogenic	0.993
NPHS1	O60500-1.1	A274M	Pathogenic	0.987
NPHS1	O60500-1.1	A274N	Pathogenic	0.961
NPHS1	O60500-1.1	A274P	Pathogenic	0.939
NPHS1	O60500-1.1	A274Q	Pathogenic	0.97
NPHS1	O60500-1.1	A274R	Pathogenic	0.996
NPHS1	O60500-1.1	A274S	Pathogenic	0.954
NPHS1	O60500-1.1	A274T	Pathogenic	0.935
NPHS1	O60500-1.1	A274V	Pathogenic	0.986
NPHS1	O60500-1.1	A274W	Pathogenic	0.997
NPHS1	O60500-1.1	A274Y	Pathogenic	0.98
NPHS1	O60500-1.1	T275A	Pathogenic	0.972
NPHS1	O60500-1.1	T275C	Pathogenic	0.976
NPHS1	O60500-1.1	T275D	Pathogenic	0.982
NPHS1	O60500-1.1	T275E	Pathogenic	0.985
NPHS1	O60500-1.1	T275F	Pathogenic	0.995
NPHS1	O60500-1.1	T275G	Pathogenic	0.97
NPHS1	O60500-1.1	T275H	Pathogenic	0.944
NPHS1	O60500-1.1	T275I	Pathogenic	0.996
NPHS1	O60500-1.1	T275K	Pathogenic	0.995
NPHS1	O60500-1.1	T275L	Pathogenic	0.995
NPHS1	O60500-1.1	T275M	Pathogenic	0.99
NPHS1	O60500-1.1	T275N	Pathogenic	0.985
NPHS1	O60500-1.1	T275P	Pathogenic	0.961
NPHS1	O60500-1.1	T275Q	Pathogenic	0.975
NPHS1	O60500-1.1	T275R	Pathogenic	0.996
NPHS1	O60500-1.1	T275S	Pathogenic	0.985
NPHS1	O60500-1.1	T275V	Pathogenic	0.99
NPHS1	O60500-1.1	T275W	Pathogenic	0.999
NPHS1	O60500-1.1	T275Y	Pathogenic	0.986
NPHS1	O60500-1.1	L276A	Pathogenic	0.995
NPHS1	O60500-1.1	L276C	Pathogenic	0.979
NPHS1	O60500-1.1	L276D	Pathogenic	0.994
NPHS1	O60500-1.1	L276E	Pathogenic	0.993
NPHS1	O60500-1.1	L276F	Pathogenic	0.936
NPHS1	O60500-1.1	L276G	Pathogenic	0.993
NPHS1	O60500-1.1	L276H	Pathogenic	0.973
NPHS1	O60500-1.1	L276I	Pathogenic	0.962
NPHS1	O60500-1.1	L276K	Pathogenic	0.997
NPHS1	O60500-1.1	L276M	Pathogenic	0.978
NPHS1	O60500-1.1	L276N	Pathogenic	0.994
NPHS1	O60500-1.1	L276P	Pathogenic	0.966
NPHS1	O60500-1.1	L276Q	Pathogenic	0.99
NPHS1	O60500-1.1	L276R	Pathogenic	0.998
NPHS1	O60500-1.1	L276S	Pathogenic	0.995
NPHS1	O60500-1.1	L276T	Pathogenic	0.992
NPHS1	O60500-1.1	L276V	Pathogenic	0.979
NPHS1	O60500-1.1	L276W	Pathogenic	0.962
NPHS1	O60500-1.1	L276Y	Pathogenic	0.968
NPHS1	O60500-1.1	Q277A	Pathogenic	0.993
NPHS1	O60500-1.1	Q277C	Pathogenic	0.991
NPHS1	O60500-1.1	Q277D	Pathogenic	0.992
NPHS1	O60500-1.1	Q277E	Pathogenic	0.993
NPHS1	O60500-1.1	Q277F	Pathogenic	0.997
NPHS1	O60500-1.1	Q277G	Pathogenic	0.989
NPHS1	O60500-1.1	Q277H	Pathogenic	0.983
NPHS1	O60500-1.1	Q277I	Pathogenic	0.996
NPHS1	O60500-1.1	Q277K	Pathogenic	0.996
NPHS1	O60500-1.1	Q277L	Pathogenic	0.997
NPHS1	O60500-1.1	Q277M	Pathogenic	0.997
NPHS1	O60500-1.1	Q277N	Pathogenic	0.988
NPHS1	O60500-1.1	Q277P	Pathogenic	0.993
NPHS1	O60500-1.1	Q277R	Pathogenic	0.997
NPHS1	O60500-1.1	Q277S	Pathogenic	0.991
NPHS1	O60500-1.1	Q277T	Pathogenic	0.986
NPHS1	O60500-1.1	Q277V	Pathogenic	0.993
NPHS1	O60500-1.1	Q277W	Pathogenic	0.999
NPHS1	O60500-1.1	Q277Y	Pathogenic	0.996
NPHS1	O60500-1.1	W278A	Pathogenic	1.0
NPHS1	O60500-1.1	W278C	Pathogenic	1.0
NPHS1	O60500-1.1	W278D	Pathogenic	1.0
NPHS1	O60500-1.1	W278E	Pathogenic	1.0
NPHS1	O60500-1.1	W278F	Pathogenic	0.999
NPHS1	O60500-1.1	W278G	Pathogenic	1.0
NPHS1	O60500-1.1	W278H	Pathogenic	1.0
NPHS1	O60500-1.1	W278I	Pathogenic	0.998
NPHS1	O60500-1.1	W278K	Pathogenic	1.0
NPHS1	O60500-1.1	W278L	Pathogenic	0.999
NPHS1	O60500-1.1	W278M	Pathogenic	1.0
NPHS1	O60500-1.1	W278N	Pathogenic	1.0
NPHS1	O60500-1.1	W278P	Pathogenic	1.0
NPHS1	O60500-1.1	W278Q	Pathogenic	1.0
NPHS1	O60500-1.1	W278R	Pathogenic	1.0
NPHS1	O60500-1.1	W278S	Pathogenic	1.0
NPHS1	O60500-1.1	W278T	Pathogenic	1.0
NPHS1	O60500-1.1	W278V	Pathogenic	0.999
NPHS1	O60500-1.1	W278Y	Pathogenic	1.0
NPHS1	O60500-1.1	L279A	Pathogenic	0.87
NPHS1	O60500-1.1	L279C	Pathogenic	0.611
NPHS1	O60500-1.1	L279D	Pathogenic	0.851
NPHS1	O60500-1.1	L279E	Pathogenic	0.82
NPHS1	O60500-1.1	L279F	Neutral	0.326
NPHS1	O60500-1.1	L279G	Pathogenic	0.834
NPHS1	O60500-1.1	L279H	Pathogenic	0.54
NPHS1	O60500-1.1	L279I	Neutral	0.459
NPHS1	O60500-1.1	L279K	Pathogenic	0.913
NPHS1	O60500-1.1	L279M	Pathogenic	0.594
NPHS1	O60500-1.1	L279N	Pathogenic	0.855
NPHS1	O60500-1.1	L279P	Neutral	0.487
NPHS1	O60500-1.1	L279Q	Pathogenic	0.765
NPHS1	O60500-1.1	L279R	Pathogenic	0.936
NPHS1	O60500-1.1	L279S	Pathogenic	0.867
NPHS1	O60500-1.1	L279T	Pathogenic	0.797
NPHS1	O60500-1.1	L279V	Pathogenic	0.611
NPHS1	O60500-1.1	L279W	Neutral	0.456
NPHS1	O60500-1.1	L279Y	Neutral	0.497
NPHS1	O60500-1.1	K280A	Pathogenic	1.0
NPHS1	O60500-1.1	K280C	Pathogenic	1.0
NPHS1	O60500-1.1	K280D	Pathogenic	0.997
NPHS1	O60500-1.1	K280E	Pathogenic	0.999
NPHS1	O60500-1.1	K280F	Pathogenic	1.0
NPHS1	O60500-1.1	K280G	Pathogenic	1.0
NPHS1	O60500-1.1	K280H	Pathogenic	0.999
NPHS1	O60500-1.1	K280I	Pathogenic	1.0
NPHS1	O60500-1.1	K280L	Pathogenic	1.0
NPHS1	O60500-1.1	K280M	Pathogenic	1.0
NPHS1	O60500-1.1	K280N	Pathogenic	0.998
NPHS1	O60500-1.1	K280P	Pathogenic	1.0
NPHS1	O60500-1.1	K280Q	Pathogenic	0.999
NPHS1	O60500-1.1	K280R	Pathogenic	0.998
NPHS1	O60500-1.1	K280S	Pathogenic	1.0
NPHS1	O60500-1.1	K280T	Pathogenic	0.999
NPHS1	O60500-1.1	K280V	Pathogenic	1.0
NPHS1	O60500-1.1	K280W	Pathogenic	1.0
NPHS1	O60500-1.1	K280Y	Pathogenic	0.999
NPHS1	O60500-1.1	N281A	Pathogenic	0.99
NPHS1	O60500-1.1	N281C	Pathogenic	0.992
NPHS1	O60500-1.1	N281D	Pathogenic	0.985
NPHS1	O60500-1.1	N281E	Pathogenic	0.977
NPHS1	O60500-1.1	N281F	Pathogenic	0.999
NPHS1	O60500-1.1	N281G	Pathogenic	0.996
NPHS1	O60500-1.1	N281H	Pathogenic	0.996
NPHS1	O60500-1.1	N281I	Pathogenic	0.998
NPHS1	O60500-1.1	N281K	Pathogenic	0.993
NPHS1	O60500-1.1	N281L	Pathogenic	0.998
NPHS1	O60500-1.1	N281M	Pathogenic	0.997
NPHS1	O60500-1.1	N281P	Pathogenic	0.991
NPHS1	O60500-1.1	N281Q	Pathogenic	0.988
NPHS1	O60500-1.1	N281R	Pathogenic	0.995
NPHS1	O60500-1.1	N281S	Pathogenic	0.994
NPHS1	O60500-1.1	N281T	Pathogenic	0.991
NPHS1	O60500-1.1	N281V	Pathogenic	0.994
NPHS1	O60500-1.1	N281W	Pathogenic	1.0
NPHS1	O60500-1.1	N281Y	Pathogenic	0.997
NPHS1	O60500-1.1	G282A	Pathogenic	0.771
NPHS1	O60500-1.1	G282C	Pathogenic	0.812
NPHS1	O60500-1.1	G282D	Pathogenic	0.888
NPHS1	O60500-1.1	G282E	Pathogenic	0.869
NPHS1	O60500-1.1	G282F	Pathogenic	0.979
NPHS1	O60500-1.1	G282H	Pathogenic	0.795
NPHS1	O60500-1.1	G282I	Pathogenic	0.96
NPHS1	O60500-1.1	G282K	Pathogenic	0.954
NPHS1	O60500-1.1	G282L	Pathogenic	0.954
NPHS1	O60500-1.1	G282M	Pathogenic	0.939
NPHS1	O60500-1.1	G282N	Pathogenic	0.912
NPHS1	O60500-1.1	G282P	Pathogenic	0.827
NPHS1	O60500-1.1	G282Q	Pathogenic	0.801
NPHS1	O60500-1.1	G282R	Pathogenic	0.967
NPHS1	O60500-1.1	G282S	Pathogenic	0.721
NPHS1	O60500-1.1	G282T	Pathogenic	0.721
NPHS1	O60500-1.1	G282V	Pathogenic	0.906
NPHS1	O60500-1.1	G282W	Pathogenic	0.996
NPHS1	O60500-1.1	G282Y	Pathogenic	0.939
NPHS1	O60500-1.1	Q283A	Neutral	0.175
NPHS1	O60500-1.1	Q283C	Neutral	0.143
NPHS1	O60500-1.1	Q283D	Neutral	0.157
NPHS1	O60500-1.1	Q283E	Neutral	0.182
NPHS1	O60500-1.1	Q283F	Neutral	0.319
NPHS1	O60500-1.1	Q283G	Neutral	0.124
NPHS1	O60500-1.1	Q283H	Neutral	0.081
NPHS1	O60500-1.1	Q283I	Neutral	0.27
NPHS1	O60500-1.1	Q283K	Neutral	0.268
NPHS1	O60500-1.1	Q283L	Neutral	0.321
NPHS1	O60500-1.1	Q283M	Neutral	0.343
NPHS1	O60500-1.1	Q283N	Neutral	0.114
NPHS1	O60500-1.1	Q283P	Neutral	0.185
NPHS1	O60500-1.1	Q283R	Neutral	0.337
NPHS1	O60500-1.1	Q283S	Neutral	0.141
NPHS1	O60500-1.1	Q283T	Neutral	0.096
NPHS1	O60500-1.1	Q283V	Neutral	0.183
NPHS1	O60500-1.1	Q283W	Pathogenic	0.729
NPHS1	O60500-1.1	Q283Y	Neutral	0.259
NPHS1	O60500-1.1	P284A	Pathogenic	0.504
NPHS1	O60500-1.1	P284C	Neutral	0.19
NPHS1	O60500-1.1	P284D	Pathogenic	0.75
NPHS1	O60500-1.1	P284E	Pathogenic	0.791
NPHS1	O60500-1.1	P284F	Pathogenic	0.579
NPHS1	O60500-1.1	P284G	Pathogenic	0.628
NPHS1	O60500-1.1	P284H	Neutral	0.499
NPHS1	O60500-1.1	P284I	Pathogenic	0.618
NPHS1	O60500-1.1	P284K	Pathogenic	0.922
NPHS1	O60500-1.1	P284L	Pathogenic	0.581
NPHS1	O60500-1.1	P284M	Pathogenic	0.508
NPHS1	O60500-1.1	P284N	Pathogenic	0.638
NPHS1	O60500-1.1	P284Q	Pathogenic	0.696
NPHS1	O60500-1.1	P284R	Pathogenic	0.917
NPHS1	O60500-1.1	P284S	Pathogenic	0.596
NPHS1	O60500-1.1	P284T	Neutral	0.406
NPHS1	O60500-1.1	P284V	Neutral	0.392
NPHS1	O60500-1.1	P284W	Pathogenic	0.841
NPHS1	O60500-1.1	P284Y	Neutral	0.408
NPHS1	O60500-1.1	V285A	Neutral	0.388
NPHS1	O60500-1.1	V285C	Neutral	0.091
NPHS1	O60500-1.1	V285D	Neutral	0.35
NPHS1	O60500-1.1	V285E	Neutral	0.343
NPHS1	O60500-1.1	V285F	Neutral	0.176
NPHS1	O60500-1.1	V285G	Neutral	0.321
NPHS1	O60500-1.1	V285H	Neutral	0.121
NPHS1	O60500-1.1	V285I	Neutral	0.454
NPHS1	O60500-1.1	V285K	Pathogenic	0.62
NPHS1	O60500-1.1	V285L	Neutral	0.243
NPHS1	O60500-1.1	V285M	Neutral	0.138
NPHS1	O60500-1.1	V285N	Neutral	0.272
NPHS1	O60500-1.1	V285P	Neutral	0.082
NPHS1	O60500-1.1	V285Q	Neutral	0.24
NPHS1	O60500-1.1	V285R	Pathogenic	0.603
NPHS1	O60500-1.1	V285S	Neutral	0.292
NPHS1	O60500-1.1	V285T	Neutral	0.27
NPHS1	O60500-1.1	V285W	Neutral	0.27
NPHS1	O60500-1.1	V285Y	Neutral	0.133
NPHS1	O60500-1.1	S286A	Pathogenic	0.873
NPHS1	O60500-1.1	S286C	Pathogenic	0.909
NPHS1	O60500-1.1	S286D	Pathogenic	0.916
NPHS1	O60500-1.1	S286E	Pathogenic	0.932
NPHS1	O60500-1.1	S286F	Pathogenic	0.986
NPHS1	O60500-1.1	S286G	Pathogenic	0.82
NPHS1	O60500-1.1	S286H	Pathogenic	0.857
NPHS1	O60500-1.1	S286I	Pathogenic	0.982
NPHS1	O60500-1.1	S286K	Pathogenic	0.977
NPHS1	O60500-1.1	S286L	Pathogenic	0.979
NPHS1	O60500-1.1	S286M	Pathogenic	0.973
NPHS1	O60500-1.1	S286N	Pathogenic	0.934
NPHS1	O60500-1.1	S286P	Pathogenic	0.881
NPHS1	O60500-1.1	S286Q	Pathogenic	0.892
NPHS1	O60500-1.1	S286R	Pathogenic	0.976
NPHS1	O60500-1.1	S286T	Pathogenic	0.899
NPHS1	O60500-1.1	S286V	Pathogenic	0.937
NPHS1	O60500-1.1	S286W	Pathogenic	0.995
NPHS1	O60500-1.1	S286Y	Pathogenic	0.959
NPHS1	O60500-1.1	T287A	Pathogenic	0.688
NPHS1	O60500-1.1	T287C	Pathogenic	0.72
NPHS1	O60500-1.1	T287D	Pathogenic	0.781
NPHS1	O60500-1.1	T287E	Pathogenic	0.804
NPHS1	O60500-1.1	T287F	Pathogenic	0.929
NPHS1	O60500-1.1	T287G	Pathogenic	0.678
NPHS1	O60500-1.1	T287H	Pathogenic	0.519
NPHS1	O60500-1.1	T287I	Pathogenic	0.939
NPHS1	O60500-1.1	T287K	Pathogenic	0.927
NPHS1	O60500-1.1	T287L	Pathogenic	0.93
NPHS1	O60500-1.1	T287M	Pathogenic	0.868
NPHS1	O60500-1.1	T287N	Pathogenic	0.809
NPHS1	O60500-1.1	T287P	Pathogenic	0.612
NPHS1	O60500-1.1	T287Q	Pathogenic	0.712
NPHS1	O60500-1.1	T287R	Pathogenic	0.947
NPHS1	O60500-1.1	T287S	Pathogenic	0.803
NPHS1	O60500-1.1	T287V	Pathogenic	0.86
NPHS1	O60500-1.1	T287W	Pathogenic	0.981
NPHS1	O60500-1.1	T287Y	Pathogenic	0.815
NPHS1	O60500-1.1	A288C	Neutral	0.099
NPHS1	O60500-1.1	A288D	Neutral	0.092
NPHS1	O60500-1.1	A288E	Neutral	0.16
NPHS1	O60500-1.1	A288F	Neutral	0.344
NPHS1	O60500-1.1	A288G	Neutral	0.06
NPHS1	O60500-1.1	A288H	Neutral	0.048
NPHS1	O60500-1.1	A288I	Neutral	0.381
NPHS1	O60500-1.1	A288K	Neutral	0.373
NPHS1	O60500-1.1	A288L	Neutral	0.346
NPHS1	O60500-1.1	A288M	Neutral	0.208
NPHS1	O60500-1.1	A288N	Neutral	0.082
NPHS1	O60500-1.1	A288P	Neutral	0.052
NPHS1	O60500-1.1	A288Q	Neutral	0.103
NPHS1	O60500-1.1	A288R	Neutral	0.452
NPHS1	O60500-1.1	A288S	Neutral	0.069
NPHS1	O60500-1.1	A288T	Neutral	0.049
NPHS1	O60500-1.1	A288V	Neutral	0.197
NPHS1	O60500-1.1	A288W	Pathogenic	0.575
NPHS1	O60500-1.1	A288Y	Neutral	0.15
NPHS1	O60500-1.1	W289A	Pathogenic	1.0
NPHS1	O60500-1.1	W289C	Pathogenic	1.0
NPHS1	O60500-1.1	W289D	Pathogenic	1.0
NPHS1	O60500-1.1	W289E	Pathogenic	1.0
NPHS1	O60500-1.1	W289F	Pathogenic	1.0
NPHS1	O60500-1.1	W289G	Pathogenic	1.0
NPHS1	O60500-1.1	W289H	Pathogenic	1.0
NPHS1	O60500-1.1	W289I	Pathogenic	0.998
NPHS1	O60500-1.1	W289K	Pathogenic	1.0
NPHS1	O60500-1.1	W289L	Pathogenic	0.999
NPHS1	O60500-1.1	W289M	Pathogenic	1.0
NPHS1	O60500-1.1	W289N	Pathogenic	1.0
NPHS1	O60500-1.1	W289P	Pathogenic	1.0
NPHS1	O60500-1.1	W289Q	Pathogenic	1.0
NPHS1	O60500-1.1	W289R	Pathogenic	1.0
NPHS1	O60500-1.1	W289S	Pathogenic	1.0
NPHS1	O60500-1.1	W289T	Pathogenic	1.0
NPHS1	O60500-1.1	W289V	Pathogenic	1.0
NPHS1	O60500-1.1	W289Y	Pathogenic	1.0
NPHS1	O60500-1.1	G290A	Neutral	0.427
NPHS1	O60500-1.1	G290C	Neutral	0.49
NPHS1	O60500-1.1	G290D	Pathogenic	0.637
NPHS1	O60500-1.1	G290E	Pathogenic	0.597
NPHS1	O60500-1.1	G290F	Pathogenic	0.91
NPHS1	O60500-1.1	G290H	Neutral	0.463
NPHS1	O60500-1.1	G290I	Pathogenic	0.843
NPHS1	O60500-1.1	G290K	Pathogenic	0.822
NPHS1	O60500-1.1	G290L	Pathogenic	0.822
NPHS1	O60500-1.1	G290M	Pathogenic	0.774
NPHS1	O60500-1.1	G290N	Pathogenic	0.696
NPHS1	O60500-1.1	G290P	Pathogenic	0.515
NPHS1	O60500-1.1	G290Q	Neutral	0.472
NPHS1	O60500-1.1	G290R	Pathogenic	0.865
NPHS1	O60500-1.1	G290S	Neutral	0.365
NPHS1	O60500-1.1	G290T	Neutral	0.365
NPHS1	O60500-1.1	G290V	Pathogenic	0.681
NPHS1	O60500-1.1	G290W	Pathogenic	0.983
NPHS1	O60500-1.1	G290Y	Pathogenic	0.773
NPHS1	O60500-1.1	T291A	Pathogenic	0.832
NPHS1	O60500-1.1	T291C	Pathogenic	0.853
NPHS1	O60500-1.1	T291D	Pathogenic	0.89
NPHS1	O60500-1.1	T291E	Pathogenic	0.902
NPHS1	O60500-1.1	T291F	Pathogenic	0.967
NPHS1	O60500-1.1	T291G	Pathogenic	0.826
NPHS1	O60500-1.1	T291H	Pathogenic	0.709
NPHS1	O60500-1.1	T291I	Pathogenic	0.972
NPHS1	O60500-1.1	T291K	Pathogenic	0.966
NPHS1	O60500-1.1	T291L	Pathogenic	0.968
NPHS1	O60500-1.1	T291M	Pathogenic	0.937
NPHS1	O60500-1.1	T291N	Pathogenic	0.905
NPHS1	O60500-1.1	T291P	Pathogenic	0.781
NPHS1	O60500-1.1	T291Q	Pathogenic	0.848
NPHS1	O60500-1.1	T291R	Pathogenic	0.976
NPHS1	O60500-1.1	T291S	Pathogenic	0.902
NPHS1	O60500-1.1	T291V	Pathogenic	0.932
NPHS1	O60500-1.1	T291W	Pathogenic	0.991
NPHS1	O60500-1.1	T291Y	Pathogenic	0.908
NPHS1	O60500-1.1	E292A	Pathogenic	0.802
NPHS1	O60500-1.1	E292C	Pathogenic	0.68
NPHS1	O60500-1.1	E292D	Pathogenic	0.694
NPHS1	O60500-1.1	E292F	Pathogenic	0.919
NPHS1	O60500-1.1	E292G	Pathogenic	0.729
NPHS1	O60500-1.1	E292H	Pathogenic	0.681
NPHS1	O60500-1.1	E292I	Pathogenic	0.899
NPHS1	O60500-1.1	E292K	Pathogenic	0.718
NPHS1	O60500-1.1	E292L	Pathogenic	0.884
NPHS1	O60500-1.1	E292M	Pathogenic	0.85
NPHS1	O60500-1.1	E292N	Neutral	0.44
NPHS1	O60500-1.1	E292P	Pathogenic	0.813
NPHS1	O60500-1.1	E292Q	Pathogenic	0.719
NPHS1	O60500-1.1	E292R	Pathogenic	0.704
NPHS1	O60500-1.1	E292S	Pathogenic	0.758
NPHS1	O60500-1.1	E292T	Pathogenic	0.67
NPHS1	O60500-1.1	E292V	Pathogenic	0.811
NPHS1	O60500-1.1	E292W	Pathogenic	0.978
NPHS1	O60500-1.1	E292Y	Pathogenic	0.85
NPHS1	O60500-1.1	H293A	Neutral	0.345
NPHS1	O60500-1.1	H293C	Neutral	0.381
NPHS1	O60500-1.1	H293D	Pathogenic	0.568
NPHS1	O60500-1.1	H293E	Pathogenic	0.512
NPHS1	O60500-1.1	H293F	Pathogenic	0.761
NPHS1	O60500-1.1	H293G	Neutral	0.436
NPHS1	O60500-1.1	H293I	Pathogenic	0.53
NPHS1	O60500-1.1	H293K	Pathogenic	0.59
NPHS1	O60500-1.1	H293L	Neutral	0.492
NPHS1	O60500-1.1	H293M	Neutral	0.418
NPHS1	O60500-1.1	H293N	Pathogenic	0.669
NPHS1	O60500-1.1	H293P	Neutral	0.36
NPHS1	O60500-1.1	H293Q	Neutral	0.334
NPHS1	O60500-1.1	H293R	Pathogenic	0.749
NPHS1	O60500-1.1	H293S	Neutral	0.403
NPHS1	O60500-1.1	H293T	Neutral	0.209
NPHS1	O60500-1.1	H293V	Neutral	0.358
NPHS1	O60500-1.1	H293W	Pathogenic	0.892
NPHS1	O60500-1.1	H293Y	Pathogenic	0.78
NPHS1	O60500-1.1	T294A	Neutral	0.007
NPHS1	O60500-1.1	T294C	Neutral	0.009
NPHS1	O60500-1.1	T294D	Neutral	0.012
NPHS1	O60500-1.1	T294E	Neutral	0.014
NPHS1	O60500-1.1	T294F	Neutral	0.043
NPHS1	O60500-1.1	T294G	Neutral	0.007
NPHS1	O60500-1.1	T294H	Neutral	0.004
NPHS1	O60500-1.1	T294I	Neutral	0.05
NPHS1	O60500-1.1	T294K	Neutral	0.042
NPHS1	O60500-1.1	T294L	Neutral	0.043
NPHS1	O60500-1.1	T294M	Neutral	0.022
NPHS1	O60500-1.1	T294N	Neutral	0.014
NPHS1	O60500-1.1	T294P	Neutral	0.005
NPHS1	O60500-1.1	T294Q	Neutral	0.008
NPHS1	O60500-1.1	T294R	Neutral	0.057
NPHS1	O60500-1.1	T294S	Neutral	0.014
NPHS1	O60500-1.1	T294V	Neutral	0.021
NPHS1	O60500-1.1	T294W	Neutral	0.147
NPHS1	O60500-1.1	T294Y	Neutral	0.015
NPHS1	O60500-1.1	Q295A	Neutral	0.037
NPHS1	O60500-1.1	Q295C	Neutral	0.029
NPHS1	O60500-1.1	Q295D	Neutral	0.033
NPHS1	O60500-1.1	Q295E	Neutral	0.039
NPHS1	O60500-1.1	Q295F	Neutral	0.078
NPHS1	O60500-1.1	Q295G	Neutral	0.025
NPHS1	O60500-1.1	Q295H	Neutral	0.016
NPHS1	O60500-1.1	Q295I	Neutral	0.063
NPHS1	O60500-1.1	Q295K	Neutral	0.062
NPHS1	O60500-1.1	Q295L	Neutral	0.079
NPHS1	O60500-1.1	Q295M	Neutral	0.086
NPHS1	O60500-1.1	Q295N	Neutral	0.023
NPHS1	O60500-1.1	Q295P	Neutral	0.04
NPHS1	O60500-1.1	Q295R	Neutral	0.084
NPHS1	O60500-1.1	Q295S	Neutral	0.029
NPHS1	O60500-1.1	Q295T	Neutral	0.019
NPHS1	O60500-1.1	Q295V	Neutral	0.039
NPHS1	O60500-1.1	Q295W	Neutral	0.328
NPHS1	O60500-1.1	Q295Y	Neutral	0.06
NPHS1	O60500-1.1	A296C	Neutral	0.062
NPHS1	O60500-1.1	A296D	Neutral	0.058
NPHS1	O60500-1.1	A296E	Neutral	0.103
NPHS1	O60500-1.1	A296F	Neutral	0.239
NPHS1	O60500-1.1	A296G	Neutral	0.037
NPHS1	O60500-1.1	A296H	Neutral	0.029
NPHS1	O60500-1.1	A296I	Neutral	0.27
NPHS1	O60500-1.1	A296K	Neutral	0.263
NPHS1	O60500-1.1	A296L	Neutral	0.241
NPHS1	O60500-1.1	A296M	Neutral	0.136
NPHS1	O60500-1.1	A296N	Neutral	0.051
NPHS1	O60500-1.1	A296P	Neutral	0.032
NPHS1	O60500-1.1	A296Q	Neutral	0.065
NPHS1	O60500-1.1	A296R	Neutral	0.332
NPHS1	O60500-1.1	A296S	Neutral	0.043
NPHS1	O60500-1.1	A296T	Neutral	0.03
NPHS1	O60500-1.1	A296V	Neutral	0.128
NPHS1	O60500-1.1	A296W	Neutral	0.449
NPHS1	O60500-1.1	A296Y	Neutral	0.096
NPHS1	O60500-1.1	V297A	Neutral	0.146
NPHS1	O60500-1.1	V297C	Neutral	0.026
NPHS1	O60500-1.1	V297D	Neutral	0.127
NPHS1	O60500-1.1	V297E	Neutral	0.123
NPHS1	O60500-1.1	V297F	Neutral	0.054
NPHS1	O60500-1.1	V297G	Neutral	0.113
NPHS1	O60500-1.1	V297H	Neutral	0.036
NPHS1	O60500-1.1	V297I	Neutral	0.183
NPHS1	O60500-1.1	V297K	Neutral	0.305
NPHS1	O60500-1.1	V297L	Neutral	0.079
NPHS1	O60500-1.1	V297M	Neutral	0.041
NPHS1	O60500-1.1	V297N	Neutral	0.091
NPHS1	O60500-1.1	V297P	Neutral	0.024
NPHS1	O60500-1.1	V297Q	Neutral	0.078
NPHS1	O60500-1.1	V297R	Neutral	0.29
NPHS1	O60500-1.1	V297S	Neutral	0.1
NPHS1	O60500-1.1	V297T	Neutral	0.091
NPHS1	O60500-1.1	V297W	Neutral	0.09
NPHS1	O60500-1.1	V297Y	Neutral	0.04
NPHS1	O60500-1.1	A298C	Pathogenic	0.867
NPHS1	O60500-1.1	A298D	Pathogenic	0.857
NPHS1	O60500-1.1	A298E	Pathogenic	0.919
NPHS1	O60500-1.1	A298F	Pathogenic	0.969
NPHS1	O60500-1.1	A298G	Pathogenic	0.791
NPHS1	O60500-1.1	A298H	Pathogenic	0.748
NPHS1	O60500-1.1	A298I	Pathogenic	0.973
NPHS1	O60500-1.1	A298K	Pathogenic	0.972
NPHS1	O60500-1.1	A298L	Pathogenic	0.969
NPHS1	O60500-1.1	A298M	Pathogenic	0.94
NPHS1	O60500-1.1	A298N	Pathogenic	0.84
NPHS1	O60500-1.1	A298P	Pathogenic	0.764
NPHS1	O60500-1.1	A298Q	Pathogenic	0.872
NPHS1	O60500-1.1	A298R	Pathogenic	0.98
NPHS1	O60500-1.1	A298S	Pathogenic	0.814
NPHS1	O60500-1.1	A298T	Pathogenic	0.753
NPHS1	O60500-1.1	A298V	Pathogenic	0.935
NPHS1	O60500-1.1	A298W	Pathogenic	0.988
NPHS1	O60500-1.1	A298Y	Pathogenic	0.912
NPHS1	O60500-1.1	R299A	Pathogenic	0.982
NPHS1	O60500-1.1	R299C	Pathogenic	0.977
NPHS1	O60500-1.1	R299D	Pathogenic	0.806
NPHS1	O60500-1.1	R299E	Pathogenic	0.88
NPHS1	O60500-1.1	R299F	Pathogenic	0.978
NPHS1	O60500-1.1	R299G	Pathogenic	0.973
NPHS1	O60500-1.1	R299H	Pathogenic	0.949
NPHS1	O60500-1.1	R299I	Pathogenic	0.983
NPHS1	O60500-1.1	R299K	Pathogenic	0.84
NPHS1	O60500-1.1	R299L	Pathogenic	0.987
NPHS1	O60500-1.1	R299M	Pathogenic	0.982
NPHS1	O60500-1.1	R299N	Pathogenic	0.914
NPHS1	O60500-1.1	R299P	Pathogenic	0.975
NPHS1	O60500-1.1	R299Q	Pathogenic	0.948
NPHS1	O60500-1.1	R299S	Pathogenic	0.966
NPHS1	O60500-1.1	R299T	Pathogenic	0.965
NPHS1	O60500-1.1	R299V	Pathogenic	0.975
NPHS1	O60500-1.1	R299W	Pathogenic	0.989
NPHS1	O60500-1.1	R299Y	Pathogenic	0.944
NPHS1	O60500-1.1	S300A	Pathogenic	0.962
NPHS1	O60500-1.1	S300C	Pathogenic	0.973
NPHS1	O60500-1.1	S300D	Pathogenic	0.976
NPHS1	O60500-1.1	S300E	Pathogenic	0.98
NPHS1	O60500-1.1	S300F	Pathogenic	0.996
NPHS1	O60500-1.1	S300G	Pathogenic	0.943
NPHS1	O60500-1.1	S300H	Pathogenic	0.956
NPHS1	O60500-1.1	S300I	Pathogenic	0.995
NPHS1	O60500-1.1	S300K	Pathogenic	0.994
NPHS1	O60500-1.1	S300L	Pathogenic	0.994
NPHS1	O60500-1.1	S300M	Pathogenic	0.992
NPHS1	O60500-1.1	S300N	Pathogenic	0.981
NPHS1	O60500-1.1	S300P	Pathogenic	0.964
NPHS1	O60500-1.1	S300Q	Pathogenic	0.968
NPHS1	O60500-1.1	S300R	Pathogenic	0.993
NPHS1	O60500-1.1	S300T	Pathogenic	0.97
NPHS1	O60500-1.1	S300V	Pathogenic	0.982
NPHS1	O60500-1.1	S300W	Pathogenic	0.998
NPHS1	O60500-1.1	S300Y	Pathogenic	0.989
NPHS1	O60500-1.1	V301A	Neutral	0.012
NPHS1	O60500-1.1	V301C	Neutral	0.002
NPHS1	O60500-1.1	V301D	Neutral	0.01
NPHS1	O60500-1.1	V301E	Neutral	0.01
NPHS1	O60500-1.1	V301F	Neutral	0.004
NPHS1	O60500-1.1	V301G	Neutral	0.009
NPHS1	O60500-1.1	V301H	Neutral	0.003
NPHS1	O60500-1.1	V301I	Neutral	0.016
NPHS1	O60500-1.1	V301K	Neutral	0.031
NPHS1	O60500-1.1	V301L	Neutral	0.006
NPHS1	O60500-1.1	V301M	Neutral	0.003
NPHS1	O60500-1.1	V301N	Neutral	0.007
NPHS1	O60500-1.1	V301P	Neutral	0.002
NPHS1	O60500-1.1	V301Q	Neutral	0.006
NPHS1	O60500-1.1	V301R	Neutral	0.029
NPHS1	O60500-1.1	V301S	Neutral	0.008
NPHS1	O60500-1.1	V301T	Neutral	0.007
NPHS1	O60500-1.1	V301W	Neutral	0.007
NPHS1	O60500-1.1	V301Y	Neutral	0.003
NPHS1	O60500-1.1	L302A	Pathogenic	0.99
NPHS1	O60500-1.1	L302C	Pathogenic	0.957
NPHS1	O60500-1.1	L302D	Pathogenic	0.988
NPHS1	O60500-1.1	L302E	Pathogenic	0.985
NPHS1	O60500-1.1	L302F	Pathogenic	0.874
NPHS1	O60500-1.1	L302G	Pathogenic	0.986
NPHS1	O60500-1.1	L302H	Pathogenic	0.944
NPHS1	O60500-1.1	L302I	Pathogenic	0.924
NPHS1	O60500-1.1	L302K	Pathogenic	0.993
NPHS1	O60500-1.1	L302M	Pathogenic	0.954
NPHS1	O60500-1.1	L302N	Pathogenic	0.988
NPHS1	O60500-1.1	L302P	Pathogenic	0.932
NPHS1	O60500-1.1	L302Q	Pathogenic	0.979
NPHS1	O60500-1.1	L302R	Pathogenic	0.995
NPHS1	O60500-1.1	L302S	Pathogenic	0.989
NPHS1	O60500-1.1	L302T	Pathogenic	0.982
NPHS1	O60500-1.1	L302V	Pathogenic	0.957
NPHS1	O60500-1.1	L302W	Pathogenic	0.923
NPHS1	O60500-1.1	L302Y	Pathogenic	0.934
NPHS1	O60500-1.1	V303A	Neutral	0.244
NPHS1	O60500-1.1	V303C	Neutral	0.048
NPHS1	O60500-1.1	V303D	Neutral	0.215
NPHS1	O60500-1.1	V303E	Neutral	0.21
NPHS1	O60500-1.1	V303F	Neutral	0.098
NPHS1	O60500-1.1	V303G	Neutral	0.194
NPHS1	O60500-1.1	V303H	Neutral	0.065
NPHS1	O60500-1.1	V303I	Neutral	0.297
NPHS1	O60500-1.1	V303K	Neutral	0.453
NPHS1	O60500-1.1	V303L	Neutral	0.14
NPHS1	O60500-1.1	V303M	Neutral	0.075
NPHS1	O60500-1.1	V303N	Neutral	0.159
NPHS1	O60500-1.1	V303P	Neutral	0.044
NPHS1	O60500-1.1	V303Q	Neutral	0.138
NPHS1	O60500-1.1	V303R	Neutral	0.435
NPHS1	O60500-1.1	V303S	Neutral	0.174
NPHS1	O60500-1.1	V303T	Neutral	0.158
NPHS1	O60500-1.1	V303W	Neutral	0.158
NPHS1	O60500-1.1	V303Y	Neutral	0.072
NPHS1	O60500-1.1	M304A	Pathogenic	0.993
NPHS1	O60500-1.1	M304C	Pathogenic	0.971
NPHS1	O60500-1.1	M304D	Pathogenic	0.994
NPHS1	O60500-1.1	M304E	Pathogenic	0.993
NPHS1	O60500-1.1	M304F	Pathogenic	0.976
NPHS1	O60500-1.1	M304G	Pathogenic	0.994
NPHS1	O60500-1.1	M304H	Pathogenic	0.974
NPHS1	O60500-1.1	M304I	Pathogenic	0.98
NPHS1	O60500-1.1	M304K	Pathogenic	0.997
NPHS1	O60500-1.1	M304L	Pathogenic	0.984
NPHS1	O60500-1.1	M304N	Pathogenic	0.995
NPHS1	O60500-1.1	M304P	Pathogenic	0.968
NPHS1	O60500-1.1	M304Q	Pathogenic	0.994
NPHS1	O60500-1.1	M304R	Pathogenic	0.998
NPHS1	O60500-1.1	M304S	Pathogenic	0.995
NPHS1	O60500-1.1	M304T	Pathogenic	0.988
NPHS1	O60500-1.1	M304V	Pathogenic	0.971
NPHS1	O60500-1.1	M304W	Pathogenic	0.991
NPHS1	O60500-1.1	M304Y	Pathogenic	0.954
NPHS1	O60500-1.1	T305A	Neutral	0.006
NPHS1	O60500-1.1	T305C	Neutral	0.007
NPHS1	O60500-1.1	T305D	Neutral	0.009
NPHS1	O60500-1.1	T305E	Neutral	0.011
NPHS1	O60500-1.1	T305F	Neutral	0.033
NPHS1	O60500-1.1	T305G	Neutral	0.005
NPHS1	O60500-1.1	T305H	Neutral	0.003
NPHS1	O60500-1.1	T305I	Neutral	0.039
NPHS1	O60500-1.1	T305K	Neutral	0.032
NPHS1	O60500-1.1	T305L	Neutral	0.033
NPHS1	O60500-1.1	T305M	Neutral	0.017
NPHS1	O60500-1.1	T305N	Neutral	0.011
NPHS1	O60500-1.1	T305P	Neutral	0.004
NPHS1	O60500-1.1	T305Q	Neutral	0.006
NPHS1	O60500-1.1	T305R	Neutral	0.044
NPHS1	O60500-1.1	T305S	Neutral	0.011
NPHS1	O60500-1.1	T305V	Neutral	0.016
NPHS1	O60500-1.1	T305W	Neutral	0.117
NPHS1	O60500-1.1	T305Y	Neutral	0.011
NPHS1	O60500-1.1	V306A	Pathogenic	0.883
NPHS1	O60500-1.1	V306C	Pathogenic	0.542
NPHS1	O60500-1.1	V306D	Pathogenic	0.865
NPHS1	O60500-1.1	V306E	Pathogenic	0.861
NPHS1	O60500-1.1	V306F	Pathogenic	0.717
NPHS1	O60500-1.1	V306G	Pathogenic	0.849
NPHS1	O60500-1.1	V306H	Pathogenic	0.621
NPHS1	O60500-1.1	V306I	Pathogenic	0.908
NPHS1	O60500-1.1	V306K	Pathogenic	0.951
NPHS1	O60500-1.1	V306L	Pathogenic	0.793
NPHS1	O60500-1.1	V306M	Pathogenic	0.655
NPHS1	O60500-1.1	V306N	Pathogenic	0.816
NPHS1	O60500-1.1	V306P	Pathogenic	0.517
NPHS1	O60500-1.1	V306Q	Pathogenic	0.79
NPHS1	O60500-1.1	V306R	Pathogenic	0.948
NPHS1	O60500-1.1	V306S	Pathogenic	0.831
NPHS1	O60500-1.1	V306T	Pathogenic	0.815
NPHS1	O60500-1.1	V306W	Pathogenic	0.815
NPHS1	O60500-1.1	V306Y	Pathogenic	0.647
NPHS1	O60500-1.1	R307A	Pathogenic	0.651
NPHS1	O60500-1.1	R307C	Pathogenic	0.594
NPHS1	O60500-1.1	R307D	Neutral	0.125
NPHS1	O60500-1.1	R307E	Neutral	0.202
NPHS1	O60500-1.1	R307F	Pathogenic	0.604
NPHS1	O60500-1.1	R307G	Pathogenic	0.553
NPHS1	O60500-1.1	R307H	Neutral	0.391
NPHS1	O60500-1.1	R307I	Pathogenic	0.669
NPHS1	O60500-1.1	R307K	Neutral	0.152
NPHS1	O60500-1.1	R307L	Pathogenic	0.721
NPHS1	O60500-1.1	R307M	Pathogenic	0.657
NPHS1	O60500-1.1	R307N	Neutral	0.266
NPHS1	O60500-1.1	R307P	Pathogenic	0.572
NPHS1	O60500-1.1	R307Q	Neutral	0.384
NPHS1	O60500-1.1	R307S	Neutral	0.492
NPHS1	O60500-1.1	R307T	Neutral	0.483
NPHS1	O60500-1.1	R307V	Pathogenic	0.569
NPHS1	O60500-1.1	R307W	Pathogenic	0.761
NPHS1	O60500-1.1	R307Y	Neutral	0.365
NPHS1	O60500-1.1	P308A	Pathogenic	0.949
NPHS1	O60500-1.1	P308C	Pathogenic	0.81
NPHS1	O60500-1.1	P308D	Pathogenic	0.982
NPHS1	O60500-1.1	P308E	Pathogenic	0.986
NPHS1	O60500-1.1	P308F	Pathogenic	0.962
NPHS1	O60500-1.1	P308G	Pathogenic	0.968
NPHS1	O60500-1.1	P308H	Pathogenic	0.948
NPHS1	O60500-1.1	P308I	Pathogenic	0.967
NPHS1	O60500-1.1	P308K	Pathogenic	0.995
NPHS1	O60500-1.1	P308L	Pathogenic	0.962
NPHS1	O60500-1.1	P308M	Pathogenic	0.949
NPHS1	O60500-1.1	P308N	Pathogenic	0.97
NPHS1	O60500-1.1	P308Q	Pathogenic	0.976
NPHS1	O60500-1.1	P308R	Pathogenic	0.995
NPHS1	O60500-1.1	P308S	Pathogenic	0.964
NPHS1	O60500-1.1	P308T	Pathogenic	0.926
NPHS1	O60500-1.1	P308V	Pathogenic	0.921
NPHS1	O60500-1.1	P308W	Pathogenic	0.99
NPHS1	O60500-1.1	P308Y	Pathogenic	0.926
NPHS1	O60500-1.1	E309A	Pathogenic	0.964
NPHS1	O60500-1.1	E309C	Pathogenic	0.933
NPHS1	O60500-1.1	E309D	Pathogenic	0.937
NPHS1	O60500-1.1	E309F	Pathogenic	0.987
NPHS1	O60500-1.1	E309G	Pathogenic	0.947
NPHS1	O60500-1.1	E309H	Pathogenic	0.934
NPHS1	O60500-1.1	E309I	Pathogenic	0.983
NPHS1	O60500-1.1	E309K	Pathogenic	0.944
NPHS1	O60500-1.1	E309L	Pathogenic	0.981
NPHS1	O60500-1.1	E309M	Pathogenic	0.974
NPHS1	O60500-1.1	E309N	Pathogenic	0.839
NPHS1	O60500-1.1	E309P	Pathogenic	0.966
NPHS1	O60500-1.1	E309Q	Pathogenic	0.944
NPHS1	O60500-1.1	E309R	Pathogenic	0.94
NPHS1	O60500-1.1	E309S	Pathogenic	0.954
NPHS1	O60500-1.1	E309T	Pathogenic	0.931
NPHS1	O60500-1.1	E309V	Pathogenic	0.966
NPHS1	O60500-1.1	E309W	Pathogenic	0.997
NPHS1	O60500-1.1	E309Y	Pathogenic	0.974
NPHS1	O60500-1.1	D310A	Pathogenic	0.986
NPHS1	O60500-1.1	D310C	Pathogenic	0.988
NPHS1	O60500-1.1	D310E	Pathogenic	0.987
NPHS1	O60500-1.1	D310F	Pathogenic	0.999
NPHS1	O60500-1.1	D310G	Pathogenic	0.991
NPHS1	O60500-1.1	D310H	Pathogenic	0.989
NPHS1	O60500-1.1	D310I	Pathogenic	0.998
NPHS1	O60500-1.1	D310K	Pathogenic	0.98
NPHS1	O60500-1.1	D310L	Pathogenic	0.997
NPHS1	O60500-1.1	D310M	Pathogenic	0.996
NPHS1	O60500-1.1	D310N	Pathogenic	0.975
NPHS1	O60500-1.1	D310P	Pathogenic	0.991
NPHS1	O60500-1.1	D310Q	Pathogenic	0.986
NPHS1	O60500-1.1	D310R	Pathogenic	0.978
NPHS1	O60500-1.1	D310S	Pathogenic	0.988
NPHS1	O60500-1.1	D310T	Pathogenic	0.983
NPHS1	O60500-1.1	D310V	Pathogenic	0.993
NPHS1	O60500-1.1	D310W	Pathogenic	0.999
NPHS1	O60500-1.1	D310Y	Pathogenic	0.996
NPHS1	O60500-1.1	H311A	Pathogenic	0.869
NPHS1	O60500-1.1	H311C	Pathogenic	0.886
NPHS1	O60500-1.1	H311D	Pathogenic	0.943
NPHS1	O60500-1.1	H311E	Pathogenic	0.93
NPHS1	O60500-1.1	H311F	Pathogenic	0.976
NPHS1	O60500-1.1	H311G	Pathogenic	0.907
NPHS1	O60500-1.1	H311I	Pathogenic	0.935
NPHS1	O60500-1.1	H311K	Pathogenic	0.948
NPHS1	O60500-1.1	H311L	Pathogenic	0.925
NPHS1	O60500-1.1	H311M	Pathogenic	0.901
NPHS1	O60500-1.1	H311N	Pathogenic	0.962
NPHS1	O60500-1.1	H311P	Pathogenic	0.877
NPHS1	O60500-1.1	H311Q	Pathogenic	0.864
NPHS1	O60500-1.1	H311R	Pathogenic	0.974
NPHS1	O60500-1.1	H311S	Pathogenic	0.895
NPHS1	O60500-1.1	H311T	Pathogenic	0.769
NPHS1	O60500-1.1	H311V	Pathogenic	0.876
NPHS1	O60500-1.1	H311W	Pathogenic	0.99
NPHS1	O60500-1.1	H311Y	Pathogenic	0.978
NPHS1	O60500-1.1	G312A	Neutral	0.393
NPHS1	O60500-1.1	G312C	Neutral	0.455
NPHS1	O60500-1.1	G312D	Pathogenic	0.604
NPHS1	O60500-1.1	G312E	Pathogenic	0.562
NPHS1	O60500-1.1	G312F	Pathogenic	0.898
NPHS1	O60500-1.1	G312H	Neutral	0.428
NPHS1	O60500-1.1	G312I	Pathogenic	0.824
NPHS1	O60500-1.1	G312K	Pathogenic	0.8
NPHS1	O60500-1.1	G312L	Pathogenic	0.8
NPHS1	O60500-1.1	G312M	Pathogenic	0.748
NPHS1	O60500-1.1	G312N	Pathogenic	0.666
NPHS1	O60500-1.1	G312P	Neutral	0.481
NPHS1	O60500-1.1	G312Q	Neutral	0.437
NPHS1	O60500-1.1	G312R	Pathogenic	0.848
NPHS1	O60500-1.1	G312S	Neutral	0.333
NPHS1	O60500-1.1	G312T	Neutral	0.333
NPHS1	O60500-1.1	G312V	Pathogenic	0.65
NPHS1	O60500-1.1	G312W	Pathogenic	0.981
NPHS1	O60500-1.1	G312Y	Pathogenic	0.748
NPHS1	O60500-1.1	A313C	Pathogenic	0.934
NPHS1	O60500-1.1	A313D	Pathogenic	0.929
NPHS1	O60500-1.1	A313E	Pathogenic	0.961
NPHS1	O60500-1.1	A313F	Pathogenic	0.985
NPHS1	O60500-1.1	A313G	Pathogenic	0.891
NPHS1	O60500-1.1	A313H	Pathogenic	0.866
NPHS1	O60500-1.1	A313I	Pathogenic	0.987
NPHS1	O60500-1.1	A313K	Pathogenic	0.987
NPHS1	O60500-1.1	A313L	Pathogenic	0.985
NPHS1	O60500-1.1	A313M	Pathogenic	0.971
NPHS1	O60500-1.1	A313N	Pathogenic	0.919
NPHS1	O60500-1.1	A313P	Pathogenic	0.875
NPHS1	O60500-1.1	A313Q	Pathogenic	0.937
NPHS1	O60500-1.1	A313R	Pathogenic	0.991
NPHS1	O60500-1.1	A313S	Pathogenic	0.905
NPHS1	O60500-1.1	A313T	Pathogenic	0.868
NPHS1	O60500-1.1	A313V	Pathogenic	0.969
NPHS1	O60500-1.1	A313W	Pathogenic	0.994
NPHS1	O60500-1.1	A313Y	Pathogenic	0.958
NPHS1	O60500-1.1	Q314A	Neutral	0.029
NPHS1	O60500-1.1	Q314C	Neutral	0.023
NPHS1	O60500-1.1	Q314D	Neutral	0.025
NPHS1	O60500-1.1	Q314E	Neutral	0.03
NPHS1	O60500-1.1	Q314F	Neutral	0.061
NPHS1	O60500-1.1	Q314G	Neutral	0.019
NPHS1	O60500-1.1	Q314H	Neutral	0.012
NPHS1	O60500-1.1	Q314I	Neutral	0.049
NPHS1	O60500-1.1	Q314K	Neutral	0.049
NPHS1	O60500-1.1	Q314L	Neutral	0.062
NPHS1	O60500-1.1	Q314M	Neutral	0.068
NPHS1	O60500-1.1	Q314N	Neutral	0.018
NPHS1	O60500-1.1	Q314P	Neutral	0.031
NPHS1	O60500-1.1	Q314R	Neutral	0.066
NPHS1	O60500-1.1	Q314S	Neutral	0.022
NPHS1	O60500-1.1	Q314T	Neutral	0.015
NPHS1	O60500-1.1	Q314V	Neutral	0.03
NPHS1	O60500-1.1	Q314W	Neutral	0.273
NPHS1	O60500-1.1	Q314Y	Neutral	0.046
NPHS1	O60500-1.1	L315A	Pathogenic	0.959
NPHS1	O60500-1.1	L315C	Pathogenic	0.846
NPHS1	O60500-1.1	L315D	Pathogenic	0.952
NPHS1	O60500-1.1	L315E	Pathogenic	0.941
NPHS1	O60500-1.1	L315F	Pathogenic	0.628
NPHS1	O60500-1.1	L315G	Pathogenic	0.946
NPHS1	O60500-1.1	L315H	Pathogenic	0.804
NPHS1	O60500-1.1	L315I	Pathogenic	0.747
NPHS1	O60500-1.1	L315K	Pathogenic	0.973
NPHS1	O60500-1.1	L315M	Pathogenic	0.836
NPHS1	O60500-1.1	L315N	Pathogenic	0.954
NPHS1	O60500-1.1	L315P	Pathogenic	0.768
NPHS1	O60500-1.1	L315Q	Pathogenic	0.919
NPHS1	O60500-1.1	L315R	Pathogenic	0.981
NPHS1	O60500-1.1	L315S	Pathogenic	0.958
NPHS1	O60500-1.1	L315T	Pathogenic	0.932
NPHS1	O60500-1.1	L315V	Pathogenic	0.846
NPHS1	O60500-1.1	L315W	Pathogenic	0.745
NPHS1	O60500-1.1	L315Y	Pathogenic	0.775
NPHS1	O60500-1.1	S316A	Pathogenic	0.609
NPHS1	O60500-1.1	S316C	Pathogenic	0.693
NPHS1	O60500-1.1	S316D	Pathogenic	0.712
NPHS1	O60500-1.1	S316E	Pathogenic	0.757
NPHS1	O60500-1.1	S316F	Pathogenic	0.941
NPHS1	O60500-1.1	S316G	Pathogenic	0.509
NPHS1	O60500-1.1	S316H	Pathogenic	0.576
NPHS1	O60500-1.1	S316I	Pathogenic	0.927
NPHS1	O60500-1.1	S316K	Pathogenic	0.907
NPHS1	O60500-1.1	S316L	Pathogenic	0.915
NPHS1	O60500-1.1	S316M	Pathogenic	0.889
NPHS1	O60500-1.1	S316N	Pathogenic	0.764
NPHS1	O60500-1.1	S316P	Pathogenic	0.626
NPHS1	O60500-1.1	S316Q	Pathogenic	0.653
NPHS1	O60500-1.1	S316R	Pathogenic	0.9
NPHS1	O60500-1.1	S316T	Pathogenic	0.668
NPHS1	O60500-1.1	S316V	Pathogenic	0.771
NPHS1	O60500-1.1	S316W	Pathogenic	0.976
NPHS1	O60500-1.1	S316Y	Pathogenic	0.843
NPHS1	O60500-1.1	C317A	Pathogenic	0.981
NPHS1	O60500-1.1	C317D	Pathogenic	0.983
NPHS1	O60500-1.1	C317E	Pathogenic	0.979
NPHS1	O60500-1.1	C317F	Pathogenic	0.983
NPHS1	O60500-1.1	C317G	Pathogenic	0.975
NPHS1	O60500-1.1	C317H	Pathogenic	0.966
NPHS1	O60500-1.1	C317I	Pathogenic	0.986
NPHS1	O60500-1.1	C317K	Pathogenic	0.996
NPHS1	O60500-1.1	C317L	Pathogenic	0.983
NPHS1	O60500-1.1	C317M	Pathogenic	0.967
NPHS1	O60500-1.1	C317N	Pathogenic	0.98
NPHS1	O60500-1.1	C317P	Pathogenic	0.858
NPHS1	O60500-1.1	C317Q	Pathogenic	0.977
NPHS1	O60500-1.1	C317R	Pathogenic	0.997
NPHS1	O60500-1.1	C317S	Pathogenic	0.981
NPHS1	O60500-1.1	C317T	Pathogenic	0.966
NPHS1	O60500-1.1	C317V	Pathogenic	0.948
NPHS1	O60500-1.1	C317W	Pathogenic	0.996
NPHS1	O60500-1.1	C317Y	Pathogenic	0.954
NPHS1	O60500-1.1	E318A	Pathogenic	0.956
NPHS1	O60500-1.1	E318C	Pathogenic	0.919
NPHS1	O60500-1.1	E318D	Pathogenic	0.924
NPHS1	O60500-1.1	E318F	Pathogenic	0.984
NPHS1	O60500-1.1	E318G	Pathogenic	0.935
NPHS1	O60500-1.1	E318H	Pathogenic	0.92
NPHS1	O60500-1.1	E318I	Pathogenic	0.979
NPHS1	O60500-1.1	E318K	Pathogenic	0.932
NPHS1	O60500-1.1	E318L	Pathogenic	0.976
NPHS1	O60500-1.1	E318M	Pathogenic	0.968
NPHS1	O60500-1.1	E318N	Pathogenic	0.808
NPHS1	O60500-1.1	E318P	Pathogenic	0.959
NPHS1	O60500-1.1	E318Q	Pathogenic	0.932
NPHS1	O60500-1.1	E318R	Pathogenic	0.927
NPHS1	O60500-1.1	E318S	Pathogenic	0.944
NPHS1	O60500-1.1	E318T	Pathogenic	0.916
NPHS1	O60500-1.1	E318V	Pathogenic	0.958
NPHS1	O60500-1.1	E318W	Pathogenic	0.996
NPHS1	O60500-1.1	E318Y	Pathogenic	0.968
NPHS1	O60500-1.1	A319C	Pathogenic	0.834
NPHS1	O60500-1.1	A319D	Pathogenic	0.822
NPHS1	O60500-1.1	A319E	Pathogenic	0.897
NPHS1	O60500-1.1	A319F	Pathogenic	0.96
NPHS1	O60500-1.1	A319G	Pathogenic	0.744
NPHS1	O60500-1.1	A319H	Pathogenic	0.696
NPHS1	O60500-1.1	A319I	Pathogenic	0.966
NPHS1	O60500-1.1	A319K	Pathogenic	0.964
NPHS1	O60500-1.1	A319L	Pathogenic	0.96
NPHS1	O60500-1.1	A319M	Pathogenic	0.923
NPHS1	O60500-1.1	A319N	Pathogenic	0.802
NPHS1	O60500-1.1	A319P	Pathogenic	0.714
NPHS1	O60500-1.1	A319Q	Pathogenic	0.84
NPHS1	O60500-1.1	A319R	Pathogenic	0.974
NPHS1	O60500-1.1	A319S	Pathogenic	0.771
NPHS1	O60500-1.1	A319T	Pathogenic	0.701
NPHS1	O60500-1.1	A319V	Pathogenic	0.918
NPHS1	O60500-1.1	A319W	Pathogenic	0.984
NPHS1	O60500-1.1	A319Y	Pathogenic	0.889
NPHS1	O60500-1.1	H320A	Neutral	0.016
NPHS1	O60500-1.1	H320C	Neutral	0.019
NPHS1	O60500-1.1	H320D	Neutral	0.039
NPHS1	O60500-1.1	H320E	Neutral	0.032
NPHS1	O60500-1.1	H320F	Neutral	0.09
NPHS1	O60500-1.1	H320G	Neutral	0.023
NPHS1	O60500-1.1	H320I	Neutral	0.034
NPHS1	O60500-1.1	H320K	Neutral	0.043
NPHS1	O60500-1.1	H320L	Neutral	0.029
NPHS1	O60500-1.1	H320M	Neutral	0.022
NPHS1	O60500-1.1	H320N	Neutral	0.059
NPHS1	O60500-1.1	H320P	Neutral	0.017
NPHS1	O60500-1.1	H320Q	Neutral	0.015
NPHS1	O60500-1.1	H320R	Neutral	0.085
NPHS1	O60500-1.1	H320S	Neutral	0.02
NPHS1	O60500-1.1	H320T	Neutral	0.008
NPHS1	O60500-1.1	H320V	Neutral	0.017
NPHS1	O60500-1.1	H320W	Neutral	0.204
NPHS1	O60500-1.1	H320Y	Neutral	0.099
NPHS1	O60500-1.1	N321A	Pathogenic	0.996
NPHS1	O60500-1.1	N321C	Pathogenic	0.997
NPHS1	O60500-1.1	N321D	Pathogenic	0.993
NPHS1	O60500-1.1	N321E	Pathogenic	0.99
NPHS1	O60500-1.1	N321F	Pathogenic	0.999
NPHS1	O60500-1.1	N321G	Pathogenic	0.998
NPHS1	O60500-1.1	N321H	Pathogenic	0.998
NPHS1	O60500-1.1	N321I	Pathogenic	0.999
NPHS1	O60500-1.1	N321K	Pathogenic	0.997
NPHS1	O60500-1.1	N321L	Pathogenic	0.999
NPHS1	O60500-1.1	N321M	Pathogenic	0.999
NPHS1	O60500-1.1	N321P	Pathogenic	0.996
NPHS1	O60500-1.1	N321Q	Pathogenic	0.995
NPHS1	O60500-1.1	N321R	Pathogenic	0.998
NPHS1	O60500-1.1	N321S	Pathogenic	0.998
NPHS1	O60500-1.1	N321T	Pathogenic	0.996
NPHS1	O60500-1.1	N321V	Pathogenic	0.997
NPHS1	O60500-1.1	N321W	Pathogenic	1.0
NPHS1	O60500-1.1	N321Y	Pathogenic	0.999
NPHS1	O60500-1.1	S322A	Neutral	0.101
NPHS1	O60500-1.1	S322C	Neutral	0.14
NPHS1	O60500-1.1	S322D	Neutral	0.151
NPHS1	O60500-1.1	S322E	Neutral	0.183
NPHS1	O60500-1.1	S322F	Pathogenic	0.535
NPHS1	O60500-1.1	S322G	Neutral	0.069
NPHS1	O60500-1.1	S322H	Neutral	0.089
NPHS1	O60500-1.1	S322I	Neutral	0.475
NPHS1	O60500-1.1	S322K	Neutral	0.411
NPHS1	O60500-1.1	S322L	Neutral	0.438
NPHS1	O60500-1.1	S322M	Neutral	0.366
NPHS1	O60500-1.1	S322N	Neutral	0.189
NPHS1	O60500-1.1	S322P	Neutral	0.107
NPHS1	O60500-1.1	S322Q	Neutral	0.119
NPHS1	O60500-1.1	S322R	Neutral	0.394
NPHS1	O60500-1.1	S322T	Neutral	0.126
NPHS1	O60500-1.1	S322V	Neutral	0.195
NPHS1	O60500-1.1	S322W	Pathogenic	0.748
NPHS1	O60500-1.1	S322Y	Neutral	0.279
NPHS1	O60500-1.1	V323A	Pathogenic	0.983
NPHS1	O60500-1.1	V323C	Pathogenic	0.903
NPHS1	O60500-1.1	V323D	Pathogenic	0.981
NPHS1	O60500-1.1	V323E	Pathogenic	0.98
NPHS1	O60500-1.1	V323F	Pathogenic	0.952
NPHS1	O60500-1.1	V323G	Pathogenic	0.978
NPHS1	O60500-1.1	V323H	Pathogenic	0.928
NPHS1	O60500-1.1	V323I	Pathogenic	0.987
NPHS1	O60500-1.1	V323K	Pathogenic	0.993
NPHS1	O60500-1.1	V323L	Pathogenic	0.968
NPHS1	O60500-1.1	V323M	Pathogenic	0.937
NPHS1	O60500-1.1	V323N	Pathogenic	0.972
NPHS1	O60500-1.1	V323P	Pathogenic	0.894
NPHS1	O60500-1.1	V323Q	Pathogenic	0.967
NPHS1	O60500-1.1	V323R	Pathogenic	0.993
NPHS1	O60500-1.1	V323S	Pathogenic	0.975
NPHS1	O60500-1.1	V323T	Pathogenic	0.972
NPHS1	O60500-1.1	V323W	Pathogenic	0.972
NPHS1	O60500-1.1	V323Y	Pathogenic	0.935
NPHS1	O60500-1.1	S324A	Pathogenic	0.71
NPHS1	O60500-1.1	S324C	Pathogenic	0.78
NPHS1	O60500-1.1	S324D	Pathogenic	0.796
NPHS1	O60500-1.1	S324E	Pathogenic	0.83
NPHS1	O60500-1.1	S324F	Pathogenic	0.962
NPHS1	O60500-1.1	S324G	Pathogenic	0.62
NPHS1	O60500-1.1	S324H	Pathogenic	0.681
NPHS1	O60500-1.1	S324I	Pathogenic	0.952
NPHS1	O60500-1.1	S324K	Pathogenic	0.939
NPHS1	O60500-1.1	S324L	Pathogenic	0.945
NPHS1	O60500-1.1	S324M	Pathogenic	0.927
NPHS1	O60500-1.1	S324N	Pathogenic	0.836
NPHS1	O60500-1.1	S324P	Pathogenic	0.725
NPHS1	O60500-1.1	S324Q	Pathogenic	0.747
NPHS1	O60500-1.1	S324R	Pathogenic	0.934
NPHS1	O60500-1.1	S324T	Pathogenic	0.76
NPHS1	O60500-1.1	S324V	Pathogenic	0.841
NPHS1	O60500-1.1	S324W	Pathogenic	0.985
NPHS1	O60500-1.1	S324Y	Pathogenic	0.894
NPHS1	O60500-1.1	A325C	Neutral	0.005
NPHS1	O60500-1.1	A325D	Neutral	0.005
NPHS1	O60500-1.1	A325E	Neutral	0.009
NPHS1	O60500-1.1	A325F	Neutral	0.023
NPHS1	O60500-1.1	A325G	Neutral	0.003
NPHS1	O60500-1.1	A325H	Neutral	0.002
NPHS1	O60500-1.1	A325I	Neutral	0.027
NPHS1	O60500-1.1	A325K	Neutral	0.026
NPHS1	O60500-1.1	A325L	Neutral	0.023
NPHS1	O60500-1.1	A325M	Neutral	0.012
NPHS1	O60500-1.1	A325N	Neutral	0.004
NPHS1	O60500-1.1	A325P	Neutral	0.002
NPHS1	O60500-1.1	A325Q	Neutral	0.005
NPHS1	O60500-1.1	A325R	Neutral	0.036
NPHS1	O60500-1.1	A325S	Neutral	0.003
NPHS1	O60500-1.1	A325T	Neutral	0.002
NPHS1	O60500-1.1	A325V	Neutral	0.011
NPHS1	O60500-1.1	A325W	Neutral	0.058
NPHS1	O60500-1.1	A325Y	Neutral	0.008
NPHS1	O60500-1.1	G326A	Neutral	0.008
NPHS1	O60500-1.1	G326C	Neutral	0.01
NPHS1	O60500-1.1	G326D	Neutral	0.019
NPHS1	O60500-1.1	G326E	Neutral	0.016
NPHS1	O60500-1.1	G326F	Neutral	0.099
NPHS1	O60500-1.1	G326H	Neutral	0.009
NPHS1	O60500-1.1	G326I	Neutral	0.055
NPHS1	O60500-1.1	G326K	Neutral	0.047
NPHS1	O60500-1.1	G326L	Neutral	0.047
NPHS1	O60500-1.1	G326M	Neutral	0.036
NPHS1	O60500-1.1	G326N	Neutral	0.024
NPHS1	O60500-1.1	G326P	Neutral	0.011
NPHS1	O60500-1.1	G326Q	Neutral	0.01
NPHS1	O60500-1.1	G326R	Neutral	0.065
NPHS1	O60500-1.1	G326S	Neutral	0.006
NPHS1	O60500-1.1	G326T	Neutral	0.006
NPHS1	O60500-1.1	G326V	Neutral	0.023
NPHS1	O60500-1.1	G326W	Neutral	0.387
NPHS1	O60500-1.1	G326Y	Neutral	0.036
NPHS1	O60500-1.1	T327A	Neutral	0.075
NPHS1	O60500-1.1	T327C	Neutral	0.086
NPHS1	O60500-1.1	T327D	Neutral	0.116
NPHS1	O60500-1.1	T327E	Neutral	0.13
NPHS1	O60500-1.1	T327F	Neutral	0.324
NPHS1	O60500-1.1	T327G	Neutral	0.072
NPHS1	O60500-1.1	T327H	Neutral	0.038
NPHS1	O60500-1.1	T327I	Neutral	0.36
NPHS1	O60500-1.1	T327K	Neutral	0.318
NPHS1	O60500-1.1	T327L	Neutral	0.326
NPHS1	O60500-1.1	T327M	Neutral	0.194
NPHS1	O60500-1.1	T327N	Neutral	0.135
NPHS1	O60500-1.1	T327P	Neutral	0.055
NPHS1	O60500-1.1	T327Q	Neutral	0.083
NPHS1	O60500-1.1	T327R	Neutral	0.394
NPHS1	O60500-1.1	T327S	Neutral	0.13
NPHS1	O60500-1.1	T327V	Neutral	0.183
NPHS1	O60500-1.1	T327W	Pathogenic	0.649
NPHS1	O60500-1.1	T327Y	Neutral	0.139
NPHS1	O60500-1.1	Q328A	Pathogenic	0.895
NPHS1	O60500-1.1	Q328C	Pathogenic	0.87
NPHS1	O60500-1.1	Q328D	Pathogenic	0.882
NPHS1	O60500-1.1	Q328E	Pathogenic	0.899
NPHS1	O60500-1.1	Q328F	Pathogenic	0.95
NPHS1	O60500-1.1	Q328G	Pathogenic	0.851
NPHS1	O60500-1.1	Q328H	Pathogenic	0.781
NPHS1	O60500-1.1	Q328I	Pathogenic	0.937
NPHS1	O60500-1.1	Q328K	Pathogenic	0.937
NPHS1	O60500-1.1	Q328L	Pathogenic	0.95
NPHS1	O60500-1.1	Q328M	Pathogenic	0.955
NPHS1	O60500-1.1	Q328N	Pathogenic	0.838
NPHS1	O60500-1.1	Q328P	Pathogenic	0.902
NPHS1	O60500-1.1	Q328R	Pathogenic	0.954
NPHS1	O60500-1.1	Q328S	Pathogenic	0.869
NPHS1	O60500-1.1	Q328T	Pathogenic	0.811
NPHS1	O60500-1.1	Q328V	Pathogenic	0.901
NPHS1	O60500-1.1	Q328W	Pathogenic	0.991
NPHS1	O60500-1.1	Q328Y	Pathogenic	0.934
NPHS1	O60500-1.1	E329A	Neutral	0.187
NPHS1	O60500-1.1	E329C	Neutral	0.107
NPHS1	O60500-1.1	E329D	Neutral	0.114
NPHS1	O60500-1.1	E329F	Neutral	0.39
NPHS1	O60500-1.1	E329G	Neutral	0.132
NPHS1	O60500-1.1	E329H	Neutral	0.108
NPHS1	O60500-1.1	E329I	Neutral	0.335
NPHS1	O60500-1.1	E329K	Neutral	0.126
NPHS1	O60500-1.1	E329L	Neutral	0.302
NPHS1	O60500-1.1	E329M	Neutral	0.243
NPHS1	O60500-1.1	E329N	Neutral	0.043
NPHS1	O60500-1.1	E329P	Neutral	0.197
NPHS1	O60500-1.1	E329Q	Neutral	0.126
NPHS1	O60500-1.1	E329R	Neutral	0.119
NPHS1	O60500-1.1	E329S	Neutral	0.151
NPHS1	O60500-1.1	E329T	Neutral	0.103
NPHS1	O60500-1.1	E329V	Neutral	0.195
NPHS1	O60500-1.1	E329W	Pathogenic	0.711
NPHS1	O60500-1.1	E329Y	Neutral	0.243
NPHS1	O60500-1.1	H330A	Neutral	0.005
NPHS1	O60500-1.1	H330C	Neutral	0.005
NPHS1	O60500-1.1	H330D	Neutral	0.011
NPHS1	O60500-1.1	H330E	Neutral	0.009
NPHS1	O60500-1.1	H330F	Neutral	0.027
NPHS1	O60500-1.1	H330G	Neutral	0.007
NPHS1	O60500-1.1	H330I	Neutral	0.01
NPHS1	O60500-1.1	H330K	Neutral	0.012
NPHS1	O60500-1.1	H330L	Neutral	0.008
NPHS1	O60500-1.1	H330M	Neutral	0.006
NPHS1	O60500-1.1	H330N	Neutral	0.017
NPHS1	O60500-1.1	H330P	Neutral	0.005
NPHS1	O60500-1.1	H330Q	Neutral	0.004
NPHS1	O60500-1.1	H330R	Neutral	0.025
NPHS1	O60500-1.1	H330S	Neutral	0.006
NPHS1	O60500-1.1	H330T	Neutral	0.002
NPHS1	O60500-1.1	H330V	Neutral	0.005
NPHS1	O60500-1.1	H330W	Neutral	0.066
NPHS1	O60500-1.1	H330Y	Neutral	0.03
NPHS1	O60500-1.1	G331A	Neutral	0.091
NPHS1	O60500-1.1	G331C	Neutral	0.114
NPHS1	O60500-1.1	G331D	Neutral	0.19
NPHS1	O60500-1.1	G331E	Neutral	0.165
NPHS1	O60500-1.1	G331F	Pathogenic	0.577
NPHS1	O60500-1.1	G331H	Neutral	0.104
NPHS1	O60500-1.1	G331I	Neutral	0.419
NPHS1	O60500-1.1	G331K	Neutral	0.382
NPHS1	O60500-1.1	G331L	Neutral	0.382
NPHS1	O60500-1.1	G331M	Neutral	0.314
NPHS1	O60500-1.1	G331N	Neutral	0.235
NPHS1	O60500-1.1	G331P	Neutral	0.125
NPHS1	O60500-1.1	G331Q	Neutral	0.107
NPHS1	O60500-1.1	G331R	Neutral	0.462
NPHS1	O60500-1.1	G331S	Neutral	0.071
NPHS1	O60500-1.1	G331T	Neutral	0.072
NPHS1	O60500-1.1	G331V	Neutral	0.223
NPHS1	O60500-1.1	G331W	Pathogenic	0.887
NPHS1	O60500-1.1	G331Y	Neutral	0.314
NPHS1	O60500-1.1	I332A	Pathogenic	0.823
NPHS1	O60500-1.1	I332C	Pathogenic	0.521
NPHS1	O60500-1.1	I332D	Pathogenic	0.855
NPHS1	O60500-1.1	I332E	Pathogenic	0.76
NPHS1	O60500-1.1	I332F	Neutral	0.205
NPHS1	O60500-1.1	I332G	Pathogenic	0.776
NPHS1	O60500-1.1	I332H	Neutral	0.449
NPHS1	O60500-1.1	I332K	Pathogenic	0.829
NPHS1	O60500-1.1	I332L	Neutral	0.335
NPHS1	O60500-1.1	I332M	Neutral	0.405
NPHS1	O60500-1.1	I332N	Pathogenic	0.803
NPHS1	O60500-1.1	I332P	Neutral	0.397
NPHS1	O60500-1.1	I332Q	Pathogenic	0.602
NPHS1	O60500-1.1	I332R	Pathogenic	0.871
NPHS1	O60500-1.1	I332S	Pathogenic	0.819
NPHS1	O60500-1.1	I332T	Pathogenic	0.731
NPHS1	O60500-1.1	I332V	Pathogenic	0.708
NPHS1	O60500-1.1	I332W	Neutral	0.223
NPHS1	O60500-1.1	I332Y	Neutral	0.406
NPHS1	O60500-1.1	T333A	Neutral	0.045
NPHS1	O60500-1.1	T333C	Neutral	0.053
NPHS1	O60500-1.1	T333D	Neutral	0.072
NPHS1	O60500-1.1	T333E	Neutral	0.081
NPHS1	O60500-1.1	T333F	Neutral	0.221
NPHS1	O60500-1.1	T333G	Neutral	0.044
NPHS1	O60500-1.1	T333H	Neutral	0.023
NPHS1	O60500-1.1	T333I	Neutral	0.25
NPHS1	O60500-1.1	T333K	Neutral	0.216
NPHS1	O60500-1.1	T333L	Neutral	0.222
NPHS1	O60500-1.1	T333M	Neutral	0.124
NPHS1	O60500-1.1	T333N	Neutral	0.084
NPHS1	O60500-1.1	T333P	Neutral	0.033
NPHS1	O60500-1.1	T333Q	Neutral	0.051
NPHS1	O60500-1.1	T333R	Neutral	0.277
NPHS1	O60500-1.1	T333S	Neutral	0.081
NPHS1	O60500-1.1	T333V	Neutral	0.117
NPHS1	O60500-1.1	T333W	Pathogenic	0.522
NPHS1	O60500-1.1	T333Y	Neutral	0.087
NPHS1	O60500-1.1	L334A	Pathogenic	0.985
NPHS1	O60500-1.1	L334C	Pathogenic	0.939
NPHS1	O60500-1.1	L334D	Pathogenic	0.982
NPHS1	O60500-1.1	L334E	Pathogenic	0.978
NPHS1	O60500-1.1	L334F	Pathogenic	0.825
NPHS1	O60500-1.1	L334G	Pathogenic	0.98
NPHS1	O60500-1.1	L334H	Pathogenic	0.919
NPHS1	O60500-1.1	L334I	Pathogenic	0.892
NPHS1	O60500-1.1	L334K	Pathogenic	0.99
NPHS1	O60500-1.1	L334M	Pathogenic	0.934
NPHS1	O60500-1.1	L334N	Pathogenic	0.983
NPHS1	O60500-1.1	L334P	Pathogenic	0.902
NPHS1	O60500-1.1	L334Q	Pathogenic	0.969
NPHS1	O60500-1.1	L334R	Pathogenic	0.993
NPHS1	O60500-1.1	L334S	Pathogenic	0.984
NPHS1	O60500-1.1	L334T	Pathogenic	0.974
NPHS1	O60500-1.1	L334V	Pathogenic	0.939
NPHS1	O60500-1.1	L334W	Pathogenic	0.891
NPHS1	O60500-1.1	L334Y	Pathogenic	0.906
NPHS1	O60500-1.1	Q335A	Neutral	0.349
NPHS1	O60500-1.1	Q335C	Neutral	0.296
NPHS1	O60500-1.1	Q335D	Neutral	0.319
NPHS1	O60500-1.1	Q335E	Neutral	0.359
NPHS1	O60500-1.1	Q335F	Pathogenic	0.542
NPHS1	O60500-1.1	Q335G	Neutral	0.263
NPHS1	O60500-1.1	Q335H	Neutral	0.182
NPHS1	O60500-1.1	Q335I	Neutral	0.482
NPHS1	O60500-1.1	Q335K	Neutral	0.48
NPHS1	O60500-1.1	Q335L	Pathogenic	0.544
NPHS1	O60500-1.1	Q335M	Pathogenic	0.569
NPHS1	O60500-1.1	Q335N	Neutral	0.245
NPHS1	O60500-1.1	Q335P	Neutral	0.364
NPHS1	O60500-1.1	Q335R	Pathogenic	0.562
NPHS1	O60500-1.1	Q335S	Neutral	0.293
NPHS1	O60500-1.1	Q335T	Neutral	0.212
NPHS1	O60500-1.1	Q335V	Neutral	0.362
NPHS1	O60500-1.1	Q335W	Pathogenic	0.872
NPHS1	O60500-1.1	Q335Y	Neutral	0.469
NPHS1	O60500-1.1	V336A	Pathogenic	0.986
NPHS1	O60500-1.1	V336C	Pathogenic	0.918
NPHS1	O60500-1.1	V336D	Pathogenic	0.984
NPHS1	O60500-1.1	V336E	Pathogenic	0.983
NPHS1	O60500-1.1	V336F	Pathogenic	0.96
NPHS1	O60500-1.1	V336G	Pathogenic	0.982
NPHS1	O60500-1.1	V336H	Pathogenic	0.939
NPHS1	O60500-1.1	V336I	Pathogenic	0.989
NPHS1	O60500-1.1	V336K	Pathogenic	0.995
NPHS1	O60500-1.1	V336L	Pathogenic	0.973
NPHS1	O60500-1.1	V336M	Pathogenic	0.947
NPHS1	O60500-1.1	V336N	Pathogenic	0.977
NPHS1	O60500-1.1	V336P	Pathogenic	0.91
NPHS1	O60500-1.1	V336Q	Pathogenic	0.973
NPHS1	O60500-1.1	V336R	Pathogenic	0.994
NPHS1	O60500-1.1	V336S	Pathogenic	0.979
NPHS1	O60500-1.1	V336T	Pathogenic	0.977
NPHS1	O60500-1.1	V336W	Pathogenic	0.976
NPHS1	O60500-1.1	V336Y	Pathogenic	0.945
NPHS1	O60500-1.1	T337A	Neutral	0.097
NPHS1	O60500-1.1	T337C	Neutral	0.111
NPHS1	O60500-1.1	T337D	Neutral	0.148
NPHS1	O60500-1.1	T337E	Neutral	0.166
NPHS1	O60500-1.1	T337F	Neutral	0.389
NPHS1	O60500-1.1	T337G	Neutral	0.093
NPHS1	O60500-1.1	T337H	Neutral	0.05
NPHS1	O60500-1.1	T337I	Neutral	0.428
NPHS1	O60500-1.1	T337K	Neutral	0.383
NPHS1	O60500-1.1	T337L	Neutral	0.391
NPHS1	O60500-1.1	T337M	Neutral	0.242
NPHS1	O60500-1.1	T337N	Neutral	0.171
NPHS1	O60500-1.1	T337P	Neutral	0.071
NPHS1	O60500-1.1	T337Q	Neutral	0.107
NPHS1	O60500-1.1	T337R	Neutral	0.463
NPHS1	O60500-1.1	T337S	Neutral	0.166
NPHS1	O60500-1.1	T337V	Neutral	0.23
NPHS1	O60500-1.1	T337W	Pathogenic	0.711
NPHS1	O60500-1.1	T337Y	Neutral	0.176
NPHS1	O60500-1.1	F338A	Pathogenic	0.999
NPHS1	O60500-1.1	F338C	Pathogenic	0.997
NPHS1	O60500-1.1	F338D	Pathogenic	1.0
NPHS1	O60500-1.1	F338E	Pathogenic	0.999
NPHS1	O60500-1.1	F338G	Pathogenic	1.0
NPHS1	O60500-1.1	F338H	Pathogenic	0.999
NPHS1	O60500-1.1	F338I	Pathogenic	0.991
NPHS1	O60500-1.1	F338K	Pathogenic	0.999
NPHS1	O60500-1.1	F338L	Pathogenic	0.992
NPHS1	O60500-1.1	F338M	Pathogenic	0.996
NPHS1	O60500-1.1	F338N	Pathogenic	1.0
NPHS1	O60500-1.1	F338P	Pathogenic	0.996
NPHS1	O60500-1.1	F338Q	Pathogenic	0.999
NPHS1	O60500-1.1	F338R	Pathogenic	1.0
NPHS1	O60500-1.1	F338S	Pathogenic	1.0
NPHS1	O60500-1.1	F338T	Pathogenic	0.999
NPHS1	O60500-1.1	F338V	Pathogenic	0.996
NPHS1	O60500-1.1	F338W	Pathogenic	0.998
NPHS1	O60500-1.1	F338Y	Pathogenic	0.999
NPHS1	O60500-1.1	P339A	Neutral	0.439
NPHS1	O60500-1.1	P339C	Neutral	0.153
NPHS1	O60500-1.1	P339D	Pathogenic	0.698
NPHS1	O60500-1.1	P339E	Pathogenic	0.744
NPHS1	O60500-1.1	P339F	Pathogenic	0.514
NPHS1	O60500-1.1	P339G	Pathogenic	0.565
NPHS1	O60500-1.1	P339H	Neutral	0.434
NPHS1	O60500-1.1	P339I	Pathogenic	0.555
NPHS1	O60500-1.1	P339K	Pathogenic	0.901
NPHS1	O60500-1.1	P339L	Pathogenic	0.517
NPHS1	O60500-1.1	P339M	Neutral	0.442
NPHS1	O60500-1.1	P339N	Pathogenic	0.576
NPHS1	O60500-1.1	P339Q	Pathogenic	0.637
NPHS1	O60500-1.1	P339R	Pathogenic	0.894
NPHS1	O60500-1.1	P339S	Pathogenic	0.531
NPHS1	O60500-1.1	P339T	Neutral	0.345
NPHS1	O60500-1.1	P339V	Neutral	0.331
NPHS1	O60500-1.1	P339W	Pathogenic	0.803
NPHS1	O60500-1.1	P339Y	Neutral	0.347
NPHS1	O60500-1.1	P340A	Pathogenic	0.979
NPHS1	O60500-1.1	P340C	Pathogenic	0.916
NPHS1	O60500-1.1	P340D	Pathogenic	0.993
NPHS1	O60500-1.1	P340E	Pathogenic	0.994
NPHS1	O60500-1.1	P340F	Pathogenic	0.985
NPHS1	O60500-1.1	P340G	Pathogenic	0.987
NPHS1	O60500-1.1	P340H	Pathogenic	0.979
NPHS1	O60500-1.1	P340I	Pathogenic	0.987
NPHS1	O60500-1.1	P340K	Pathogenic	0.998
NPHS1	O60500-1.1	P340L	Pathogenic	0.985
NPHS1	O60500-1.1	P340M	Pathogenic	0.98
NPHS1	O60500-1.1	P340N	Pathogenic	0.988
NPHS1	O60500-1.1	P340Q	Pathogenic	0.991
NPHS1	O60500-1.1	P340R	Pathogenic	0.998
NPHS1	O60500-1.1	P340S	Pathogenic	0.986
NPHS1	O60500-1.1	P340T	Pathogenic	0.97
NPHS1	O60500-1.1	P340V	Pathogenic	0.968
NPHS1	O60500-1.1	P340W	Pathogenic	0.996
NPHS1	O60500-1.1	P340Y	Pathogenic	0.97
NPHS1	O60500-1.1	S341A	Neutral	0.465
NPHS1	O60500-1.1	S341C	Pathogenic	0.557
NPHS1	O60500-1.1	S341D	Pathogenic	0.58
NPHS1	O60500-1.1	S341E	Pathogenic	0.635
NPHS1	O60500-1.1	S341F	Pathogenic	0.899
NPHS1	O60500-1.1	S341G	Neutral	0.366
NPHS1	O60500-1.1	S341H	Neutral	0.431
NPHS1	O60500-1.1	S341I	Pathogenic	0.876
NPHS1	O60500-1.1	S341K	Pathogenic	0.844
NPHS1	O60500-1.1	S341L	Pathogenic	0.858
NPHS1	O60500-1.1	S341M	Pathogenic	0.818
NPHS1	O60500-1.1	S341N	Pathogenic	0.643
NPHS1	O60500-1.1	S341P	Neutral	0.483
NPHS1	O60500-1.1	S341Q	Pathogenic	0.512
NPHS1	O60500-1.1	S341R	Pathogenic	0.835
NPHS1	O60500-1.1	S341T	Pathogenic	0.529
NPHS1	O60500-1.1	S341V	Pathogenic	0.652
NPHS1	O60500-1.1	S341W	Pathogenic	0.958
NPHS1	O60500-1.1	S341Y	Pathogenic	0.75
NPHS1	O60500-1.1	A342C	Neutral	0.234
NPHS1	O60500-1.1	A342D	Neutral	0.22
NPHS1	O60500-1.1	A342E	Neutral	0.346
NPHS1	O60500-1.1	A342F	Pathogenic	0.592
NPHS1	O60500-1.1	A342G	Neutral	0.151
NPHS1	O60500-1.1	A342H	Neutral	0.122
NPHS1	O60500-1.1	A342I	Pathogenic	0.631
NPHS1	O60500-1.1	A342K	Pathogenic	0.623
NPHS1	O60500-1.1	A342L	Pathogenic	0.595
NPHS1	O60500-1.1	A342M	Neutral	0.422
NPHS1	O60500-1.1	A342N	Neutral	0.198
NPHS1	O60500-1.1	A342P	Neutral	0.132
NPHS1	O60500-1.1	A342Q	Neutral	0.242
NPHS1	O60500-1.1	A342R	Pathogenic	0.696
NPHS1	O60500-1.1	A342S	Neutral	0.17
NPHS1	O60500-1.1	A342T	Neutral	0.125
NPHS1	O60500-1.1	A342V	Neutral	0.405
NPHS1	O60500-1.1	A342W	Pathogenic	0.79
NPHS1	O60500-1.1	A342Y	Neutral	0.328
NPHS1	O60500-1.1	I343A	Pathogenic	0.974
NPHS1	O60500-1.1	I343C	Pathogenic	0.897
NPHS1	O60500-1.1	I343D	Pathogenic	0.979
NPHS1	O60500-1.1	I343E	Pathogenic	0.962
NPHS1	O60500-1.1	I343F	Pathogenic	0.674
NPHS1	O60500-1.1	I343G	Pathogenic	0.965
NPHS1	O60500-1.1	I343H	Pathogenic	0.867
NPHS1	O60500-1.1	I343K	Pathogenic	0.975
NPHS1	O60500-1.1	I343L	Pathogenic	0.802
NPHS1	O60500-1.1	I343M	Pathogenic	0.845
NPHS1	O60500-1.1	I343N	Pathogenic	0.97
NPHS1	O60500-1.1	I343P	Pathogenic	0.841
NPHS1	O60500-1.1	I343Q	Pathogenic	0.924
NPHS1	O60500-1.1	I343R	Pathogenic	0.982
NPHS1	O60500-1.1	I343S	Pathogenic	0.973
NPHS1	O60500-1.1	I343T	Pathogenic	0.956
NPHS1	O60500-1.1	I343V	Pathogenic	0.951
NPHS1	O60500-1.1	I343W	Pathogenic	0.697
NPHS1	O60500-1.1	I343Y	Pathogenic	0.846
NPHS1	O60500-1.1	I344A	Neutral	0.175
NPHS1	O60500-1.1	I344C	Neutral	0.047
NPHS1	O60500-1.1	I344D	Neutral	0.213
NPHS1	O60500-1.1	I344E	Neutral	0.127
NPHS1	O60500-1.1	I344F	Neutral	0.012
NPHS1	O60500-1.1	I344G	Neutral	0.137
NPHS1	O60500-1.1	I344H	Neutral	0.036
NPHS1	O60500-1.1	I344K	Neutral	0.182
NPHS1	O60500-1.1	I344L	Neutral	0.023
NPHS1	O60500-1.1	I344M	Neutral	0.03
NPHS1	O60500-1.1	I344N	Neutral	0.157
NPHS1	O60500-1.1	I344P	Neutral	0.029
NPHS1	O60500-1.1	I344Q	Neutral	0.065
NPHS1	O60500-1.1	I344R	Neutral	0.236
NPHS1	O60500-1.1	I344S	Neutral	0.171
NPHS1	O60500-1.1	I344T	Neutral	0.111
NPHS1	O60500-1.1	I344V	Neutral	0.1
NPHS1	O60500-1.1	I344W	Neutral	0.013
NPHS1	O60500-1.1	I344Y	Neutral	0.03
NPHS1	O60500-1.1	I345A	Pathogenic	0.992
NPHS1	O60500-1.1	I345C	Pathogenic	0.969
NPHS1	O60500-1.1	I345D	Pathogenic	0.994
NPHS1	O60500-1.1	I345E	Pathogenic	0.989
NPHS1	O60500-1.1	I345F	Pathogenic	0.88
NPHS1	O60500-1.1	I345G	Pathogenic	0.99
NPHS1	O60500-1.1	I345H	Pathogenic	0.959
NPHS1	O60500-1.1	I345K	Pathogenic	0.993
NPHS1	O60500-1.1	I345L	Pathogenic	0.935
NPHS1	O60500-1.1	I345M	Pathogenic	0.951
NPHS1	O60500-1.1	I345N	Pathogenic	0.991
NPHS1	O60500-1.1	I345P	Pathogenic	0.949
NPHS1	O60500-1.1	I345Q	Pathogenic	0.977
NPHS1	O60500-1.1	I345R	Pathogenic	0.995
NPHS1	O60500-1.1	I345S	Pathogenic	0.992
NPHS1	O60500-1.1	I345T	Pathogenic	0.987
NPHS1	O60500-1.1	I345V	Pathogenic	0.986
NPHS1	O60500-1.1	I345W	Pathogenic	0.891
NPHS1	O60500-1.1	I345Y	Pathogenic	0.951
NPHS1	O60500-1.1	L346A	Pathogenic	0.972
NPHS1	O60500-1.1	L346C	Pathogenic	0.889
NPHS1	O60500-1.1	L346D	Pathogenic	0.967
NPHS1	O60500-1.1	L346E	Pathogenic	0.959
NPHS1	O60500-1.1	L346F	Pathogenic	0.713
NPHS1	O60500-1.1	L346G	Pathogenic	0.963
NPHS1	O60500-1.1	L346H	Pathogenic	0.858
NPHS1	O60500-1.1	L346I	Pathogenic	0.813
NPHS1	O60500-1.1	L346K	Pathogenic	0.982
NPHS1	O60500-1.1	L346M	Pathogenic	0.882
NPHS1	O60500-1.1	L346N	Pathogenic	0.968
NPHS1	O60500-1.1	L346P	Pathogenic	0.83
NPHS1	O60500-1.1	L346Q	Pathogenic	0.943
NPHS1	O60500-1.1	L346R	Pathogenic	0.987
NPHS1	O60500-1.1	L346S	Pathogenic	0.971
NPHS1	O60500-1.1	L346T	Pathogenic	0.953
NPHS1	O60500-1.1	L346V	Pathogenic	0.89
NPHS1	O60500-1.1	L346W	Pathogenic	0.811
NPHS1	O60500-1.1	L346Y	Pathogenic	0.835
NPHS1	O60500-1.1	G347A	Pathogenic	0.976
NPHS1	O60500-1.1	G347C	Pathogenic	0.981
NPHS1	O60500-1.1	G347D	Pathogenic	0.99
NPHS1	O60500-1.1	G347E	Pathogenic	0.988
NPHS1	O60500-1.1	G347F	Pathogenic	0.998
NPHS1	O60500-1.1	G347H	Pathogenic	0.979
NPHS1	O60500-1.1	G347I	Pathogenic	0.997
NPHS1	O60500-1.1	G347K	Pathogenic	0.996
NPHS1	O60500-1.1	G347L	Pathogenic	0.996
NPHS1	O60500-1.1	G347M	Pathogenic	0.995
NPHS1	O60500-1.1	G347N	Pathogenic	0.992
NPHS1	O60500-1.1	G347P	Pathogenic	0.983
NPHS1	O60500-1.1	G347Q	Pathogenic	0.98
NPHS1	O60500-1.1	G347R	Pathogenic	0.997
NPHS1	O60500-1.1	G347S	Pathogenic	0.969
NPHS1	O60500-1.1	G347T	Pathogenic	0.969
NPHS1	O60500-1.1	G347V	Pathogenic	0.991
NPHS1	O60500-1.1	G347W	Pathogenic	1.0
NPHS1	O60500-1.1	G347Y	Pathogenic	0.995
NPHS1	O60500-1.1	S348A	Pathogenic	0.944
NPHS1	O60500-1.1	S348C	Pathogenic	0.961
NPHS1	O60500-1.1	S348D	Pathogenic	0.964
NPHS1	O60500-1.1	S348E	Pathogenic	0.971
NPHS1	O60500-1.1	S348F	Pathogenic	0.994
NPHS1	O60500-1.1	S348G	Pathogenic	0.918
NPHS1	O60500-1.1	S348H	Pathogenic	0.936
NPHS1	O60500-1.1	S348I	Pathogenic	0.993
NPHS1	O60500-1.1	S348K	Pathogenic	0.991
NPHS1	O60500-1.1	S348L	Pathogenic	0.992
NPHS1	O60500-1.1	S348M	Pathogenic	0.989
NPHS1	O60500-1.1	S348N	Pathogenic	0.972
NPHS1	O60500-1.1	S348P	Pathogenic	0.948
NPHS1	O60500-1.1	S348Q	Pathogenic	0.953
NPHS1	O60500-1.1	S348R	Pathogenic	0.99
NPHS1	O60500-1.1	S348T	Pathogenic	0.956
NPHS1	O60500-1.1	S348V	Pathogenic	0.973
NPHS1	O60500-1.1	S348W	Pathogenic	0.998
NPHS1	O60500-1.1	S348Y	Pathogenic	0.983
NPHS1	O60500-1.1	A349C	Neutral	0.021
NPHS1	O60500-1.1	A349D	Neutral	0.019
NPHS1	O60500-1.1	A349E	Neutral	0.035
NPHS1	O60500-1.1	A349F	Neutral	0.091
NPHS1	O60500-1.1	A349G	Neutral	0.012
NPHS1	O60500-1.1	A349H	Neutral	0.009
NPHS1	O60500-1.1	A349I	Neutral	0.105
NPHS1	O60500-1.1	A349K	Neutral	0.102
NPHS1	O60500-1.1	A349L	Neutral	0.091
NPHS1	O60500-1.1	A349M	Neutral	0.048
NPHS1	O60500-1.1	A349N	Neutral	0.017
NPHS1	O60500-1.1	A349P	Neutral	0.01
NPHS1	O60500-1.1	A349Q	Neutral	0.021
NPHS1	O60500-1.1	A349R	Neutral	0.136
NPHS1	O60500-1.1	A349S	Neutral	0.014
NPHS1	O60500-1.1	A349T	Neutral	0.01
NPHS1	O60500-1.1	A349V	Neutral	0.044
NPHS1	O60500-1.1	A349W	Neutral	0.205
NPHS1	O60500-1.1	A349Y	Neutral	0.032
NPHS1	O60500-1.1	S350A	Pathogenic	0.703
NPHS1	O60500-1.1	S350C	Pathogenic	0.774
NPHS1	O60500-1.1	S350D	Pathogenic	0.79
NPHS1	O60500-1.1	S350E	Pathogenic	0.825
NPHS1	O60500-1.1	S350F	Pathogenic	0.96
NPHS1	O60500-1.1	S350G	Pathogenic	0.612
NPHS1	O60500-1.1	S350H	Pathogenic	0.673
NPHS1	O60500-1.1	S350I	Pathogenic	0.95
NPHS1	O60500-1.1	S350K	Pathogenic	0.937
NPHS1	O60500-1.1	S350L	Pathogenic	0.943
NPHS1	O60500-1.1	S350M	Pathogenic	0.924
NPHS1	O60500-1.1	S350N	Pathogenic	0.831
NPHS1	O60500-1.1	S350P	Pathogenic	0.718
NPHS1	O60500-1.1	S350Q	Pathogenic	0.741
NPHS1	O60500-1.1	S350R	Pathogenic	0.932
NPHS1	O60500-1.1	S350T	Pathogenic	0.754
NPHS1	O60500-1.1	S350V	Pathogenic	0.836
NPHS1	O60500-1.1	S350W	Pathogenic	0.984
NPHS1	O60500-1.1	S350Y	Pathogenic	0.891
NPHS1	O60500-1.1	Q351A	Neutral	0.44
NPHS1	O60500-1.1	Q351C	Neutral	0.381
NPHS1	O60500-1.1	Q351D	Neutral	0.407
NPHS1	O60500-1.1	Q351E	Neutral	0.451
NPHS1	O60500-1.1	Q351F	Pathogenic	0.634
NPHS1	O60500-1.1	Q351G	Neutral	0.343
NPHS1	O60500-1.1	Q351H	Neutral	0.246
NPHS1	O60500-1.1	Q351I	Pathogenic	0.577
NPHS1	O60500-1.1	Q351K	Pathogenic	0.576
NPHS1	O60500-1.1	Q351L	Pathogenic	0.636
NPHS1	O60500-1.1	Q351M	Pathogenic	0.659
NPHS1	O60500-1.1	Q351N	Neutral	0.322
NPHS1	O60500-1.1	Q351P	Neutral	0.457
NPHS1	O60500-1.1	Q351R	Pathogenic	0.653
NPHS1	O60500-1.1	Q351S	Neutral	0.379
NPHS1	O60500-1.1	Q351T	Neutral	0.283
NPHS1	O60500-1.1	Q351V	Neutral	0.454
NPHS1	O60500-1.1	Q351W	Pathogenic	0.909
NPHS1	O60500-1.1	Q351Y	Pathogenic	0.564
NPHS1	O60500-1.1	T352A	Neutral	0.0
NPHS1	O60500-1.1	T352C	Neutral	0.0
NPHS1	O60500-1.1	T352D	Neutral	0.001
NPHS1	O60500-1.1	T352E	Neutral	0.001
NPHS1	O60500-1.1	T352F	Neutral	0.002
NPHS1	O60500-1.1	T352G	Neutral	0.0
NPHS1	O60500-1.1	T352H	Neutral	0.0
NPHS1	O60500-1.1	T352I	Neutral	0.002
NPHS1	O60500-1.1	T352K	Neutral	0.002
NPHS1	O60500-1.1	T352L	Neutral	0.002
NPHS1	O60500-1.1	T352M	Neutral	0.001
NPHS1	O60500-1.1	T352N	Neutral	0.001
NPHS1	O60500-1.1	T352P	Neutral	0.0
NPHS1	O60500-1.1	T352Q	Neutral	0.0
NPHS1	O60500-1.1	T352R	Neutral	0.003
NPHS1	O60500-1.1	T352S	Neutral	0.001
NPHS1	O60500-1.1	T352V	Neutral	0.001
NPHS1	O60500-1.1	T352W	Neutral	0.008
NPHS1	O60500-1.1	T352Y	Neutral	0.001
NPHS1	O60500-1.1	E353A	Pathogenic	0.996
NPHS1	O60500-1.1	E353C	Pathogenic	0.992
NPHS1	O60500-1.1	E353D	Pathogenic	0.993
NPHS1	O60500-1.1	E353F	Pathogenic	0.998
NPHS1	O60500-1.1	E353G	Pathogenic	0.994
NPHS1	O60500-1.1	E353H	Pathogenic	0.992
NPHS1	O60500-1.1	E353I	Pathogenic	0.998
NPHS1	O60500-1.1	E353K	Pathogenic	0.993
NPHS1	O60500-1.1	E353L	Pathogenic	0.998
NPHS1	O60500-1.1	E353M	Pathogenic	0.997
NPHS1	O60500-1.1	E353N	Pathogenic	0.979
NPHS1	O60500-1.1	E353P	Pathogenic	0.996
NPHS1	O60500-1.1	E353Q	Pathogenic	0.993
NPHS1	O60500-1.1	E353R	Pathogenic	0.993
NPHS1	O60500-1.1	E353S	Pathogenic	0.995
NPHS1	O60500-1.1	E353T	Pathogenic	0.992
NPHS1	O60500-1.1	E353V	Pathogenic	0.996
NPHS1	O60500-1.1	E353W	Pathogenic	1.0
NPHS1	O60500-1.1	E353Y	Pathogenic	0.997
NPHS1	O60500-1.1	N354A	Pathogenic	0.874
NPHS1	O60500-1.1	N354C	Pathogenic	0.89
NPHS1	O60500-1.1	N354D	Pathogenic	0.812
NPHS1	O60500-1.1	N354E	Pathogenic	0.742
NPHS1	O60500-1.1	N354F	Pathogenic	0.982
NPHS1	O60500-1.1	N354G	Pathogenic	0.938
NPHS1	O60500-1.1	N354H	Pathogenic	0.937
NPHS1	O60500-1.1	N354I	Pathogenic	0.977
NPHS1	O60500-1.1	N354K	Pathogenic	0.9
NPHS1	O60500-1.1	N354L	Pathogenic	0.973
NPHS1	O60500-1.1	N354M	Pathogenic	0.964
NPHS1	O60500-1.1	N354P	Pathogenic	0.881
NPHS1	O60500-1.1	N354Q	Pathogenic	0.844
NPHS1	O60500-1.1	N354R	Pathogenic	0.926
NPHS1	O60500-1.1	N354S	Pathogenic	0.923
NPHS1	O60500-1.1	N354T	Pathogenic	0.885
NPHS1	O60500-1.1	N354V	Pathogenic	0.918
NPHS1	O60500-1.1	N354W	Pathogenic	0.993
NPHS1	O60500-1.1	N354Y	Pathogenic	0.964
NPHS1	O60500-1.1	K355A	Pathogenic	0.994
NPHS1	O60500-1.1	K355C	Pathogenic	0.992
NPHS1	O60500-1.1	K355D	Pathogenic	0.946
NPHS1	O60500-1.1	K355E	Pathogenic	0.969
NPHS1	O60500-1.1	K355F	Pathogenic	0.992
NPHS1	O60500-1.1	K355G	Pathogenic	0.99
NPHS1	O60500-1.1	K355H	Pathogenic	0.973
NPHS1	O60500-1.1	K355I	Pathogenic	0.994
NPHS1	O60500-1.1	K355L	Pathogenic	0.995
NPHS1	O60500-1.1	K355M	Pathogenic	0.994
NPHS1	O60500-1.1	K355N	Pathogenic	0.968
NPHS1	O60500-1.1	K355P	Pathogenic	0.994
NPHS1	O60500-1.1	K355Q	Pathogenic	0.981
NPHS1	O60500-1.1	K355R	Pathogenic	0.954
NPHS1	O60500-1.1	K355S	Pathogenic	0.992
NPHS1	O60500-1.1	K355T	Pathogenic	0.987
NPHS1	O60500-1.1	K355V	Pathogenic	0.994
NPHS1	O60500-1.1	K355W	Pathogenic	0.998
NPHS1	O60500-1.1	K355Y	Pathogenic	0.984
NPHS1	O60500-1.1	N356A	Neutral	0.066
NPHS1	O60500-1.1	N356C	Neutral	0.076
NPHS1	O60500-1.1	N356D	Neutral	0.042
NPHS1	O60500-1.1	N356E	Neutral	0.029
NPHS1	O60500-1.1	N356F	Neutral	0.353
NPHS1	O60500-1.1	N356G	Neutral	0.135
NPHS1	O60500-1.1	N356H	Neutral	0.133
NPHS1	O60500-1.1	N356I	Neutral	0.3
NPHS1	O60500-1.1	N356K	Neutral	0.084
NPHS1	O60500-1.1	N356L	Neutral	0.269
NPHS1	O60500-1.1	N356M	Neutral	0.215
NPHS1	O60500-1.1	N356P	Neutral	0.07
NPHS1	O60500-1.1	N356Q	Neutral	0.052
NPHS1	O60500-1.1	N356R	Neutral	0.113
NPHS1	O60500-1.1	N356S	Neutral	0.109
NPHS1	O60500-1.1	N356T	Neutral	0.073
NPHS1	O60500-1.1	N356V	Neutral	0.103
NPHS1	O60500-1.1	N356W	Pathogenic	0.585
NPHS1	O60500-1.1	N356Y	Neutral	0.214
NPHS1	O60500-1.1	V357A	Neutral	0.387
NPHS1	O60500-1.1	V357C	Neutral	0.09
NPHS1	O60500-1.1	V357D	Neutral	0.349
NPHS1	O60500-1.1	V357E	Neutral	0.342
NPHS1	O60500-1.1	V357F	Neutral	0.175
NPHS1	O60500-1.1	V357G	Neutral	0.32
NPHS1	O60500-1.1	V357H	Neutral	0.12
NPHS1	O60500-1.1	V357I	Neutral	0.452
NPHS1	O60500-1.1	V357K	Pathogenic	0.618
NPHS1	O60500-1.1	V357L	Neutral	0.242
NPHS1	O60500-1.1	V357M	Neutral	0.137
NPHS1	O60500-1.1	V357N	Neutral	0.27
NPHS1	O60500-1.1	V357P	Neutral	0.082
NPHS1	O60500-1.1	V357Q	Neutral	0.239
NPHS1	O60500-1.1	V357R	Pathogenic	0.601
NPHS1	O60500-1.1	V357S	Neutral	0.291
NPHS1	O60500-1.1	V357T	Neutral	0.269
NPHS1	O60500-1.1	V357W	Neutral	0.269
NPHS1	O60500-1.1	V357Y	Neutral	0.132
NPHS1	O60500-1.1	T358A	Pathogenic	0.517
NPHS1	O60500-1.1	T358C	Pathogenic	0.555
NPHS1	O60500-1.1	T358D	Pathogenic	0.634
NPHS1	O60500-1.1	T358E	Pathogenic	0.665
NPHS1	O60500-1.1	T358F	Pathogenic	0.864
NPHS1	O60500-1.1	T358G	Pathogenic	0.506
NPHS1	O60500-1.1	T358H	Neutral	0.344
NPHS1	O60500-1.1	T358I	Pathogenic	0.882
NPHS1	O60500-1.1	T358K	Pathogenic	0.861
NPHS1	O60500-1.1	T358L	Pathogenic	0.865
NPHS1	O60500-1.1	T358M	Pathogenic	0.761
NPHS1	O60500-1.1	T358N	Pathogenic	0.673
NPHS1	O60500-1.1	T358P	Neutral	0.434
NPHS1	O60500-1.1	T358Q	Pathogenic	0.545
NPHS1	O60500-1.1	T358R	Pathogenic	0.896
NPHS1	O60500-1.1	T358S	Pathogenic	0.665
NPHS1	O60500-1.1	T358V	Pathogenic	0.748
NPHS1	O60500-1.1	T358W	Pathogenic	0.961
NPHS1	O60500-1.1	T358Y	Pathogenic	0.681
NPHS1	O60500-1.1	L359A	Pathogenic	0.958
NPHS1	O60500-1.1	L359C	Pathogenic	0.842
NPHS1	O60500-1.1	L359D	Pathogenic	0.951
NPHS1	O60500-1.1	L359E	Pathogenic	0.939
NPHS1	O60500-1.1	L359F	Pathogenic	0.622
NPHS1	O60500-1.1	L359G	Pathogenic	0.944
NPHS1	O60500-1.1	L359H	Pathogenic	0.8
NPHS1	O60500-1.1	L359I	Pathogenic	0.742
NPHS1	O60500-1.1	L359K	Pathogenic	0.973
NPHS1	O60500-1.1	L359M	Pathogenic	0.832
NPHS1	O60500-1.1	L359N	Pathogenic	0.952
NPHS1	O60500-1.1	L359P	Pathogenic	0.764
NPHS1	O60500-1.1	L359Q	Pathogenic	0.917
NPHS1	O60500-1.1	L359R	Pathogenic	0.98
NPHS1	O60500-1.1	L359S	Pathogenic	0.957
NPHS1	O60500-1.1	L359T	Pathogenic	0.93
NPHS1	O60500-1.1	L359V	Pathogenic	0.842
NPHS1	O60500-1.1	L359W	Pathogenic	0.74
NPHS1	O60500-1.1	L359Y	Pathogenic	0.77
NPHS1	O60500-1.1	S360A	Pathogenic	0.746
NPHS1	O60500-1.1	S360C	Pathogenic	0.809
NPHS1	O60500-1.1	S360D	Pathogenic	0.823
NPHS1	O60500-1.1	S360E	Pathogenic	0.854
NPHS1	O60500-1.1	S360F	Pathogenic	0.968
NPHS1	O60500-1.1	S360G	Pathogenic	0.661
NPHS1	O60500-1.1	S360H	Pathogenic	0.718
NPHS1	O60500-1.1	S360I	Pathogenic	0.96
NPHS1	O60500-1.1	S360K	Pathogenic	0.948
NPHS1	O60500-1.1	S360L	Pathogenic	0.953
NPHS1	O60500-1.1	S360M	Pathogenic	0.938
NPHS1	O60500-1.1	S360N	Pathogenic	0.859
NPHS1	O60500-1.1	S360P	Pathogenic	0.759
NPHS1	O60500-1.1	S360Q	Pathogenic	0.78
NPHS1	O60500-1.1	S360R	Pathogenic	0.945
NPHS1	O60500-1.1	S360T	Pathogenic	0.791
NPHS1	O60500-1.1	S360V	Pathogenic	0.863
NPHS1	O60500-1.1	S360W	Pathogenic	0.987
NPHS1	O60500-1.1	S360Y	Pathogenic	0.91
NPHS1	O60500-1.1	C361A	Pathogenic	0.976
NPHS1	O60500-1.1	C361D	Pathogenic	0.977
NPHS1	O60500-1.1	C361E	Pathogenic	0.973
NPHS1	O60500-1.1	C361F	Pathogenic	0.978
NPHS1	O60500-1.1	C361G	Pathogenic	0.968
NPHS1	O60500-1.1	C361H	Pathogenic	0.955
NPHS1	O60500-1.1	C361I	Pathogenic	0.981
NPHS1	O60500-1.1	C361K	Pathogenic	0.994
NPHS1	O60500-1.1	C361L	Pathogenic	0.978
NPHS1	O60500-1.1	C361M	Pathogenic	0.957
NPHS1	O60500-1.1	C361N	Pathogenic	0.974
NPHS1	O60500-1.1	C361P	Pathogenic	0.822
NPHS1	O60500-1.1	C361Q	Pathogenic	0.97
NPHS1	O60500-1.1	C361R	Pathogenic	0.996
NPHS1	O60500-1.1	C361S	Pathogenic	0.975
NPHS1	O60500-1.1	C361T	Pathogenic	0.956
NPHS1	O60500-1.1	C361V	Pathogenic	0.933
NPHS1	O60500-1.1	C361W	Pathogenic	0.994
NPHS1	O60500-1.1	C361Y	Pathogenic	0.941
NPHS1	O60500-1.1	V362A	Neutral	0.004
NPHS1	O60500-1.1	V362C	Neutral	0.001
NPHS1	O60500-1.1	V362D	Neutral	0.003
NPHS1	O60500-1.1	V362E	Neutral	0.003
NPHS1	O60500-1.1	V362F	Neutral	0.001
NPHS1	O60500-1.1	V362G	Neutral	0.003
NPHS1	O60500-1.1	V362H	Neutral	0.001
NPHS1	O60500-1.1	V362I	Neutral	0.005
NPHS1	O60500-1.1	V362K	Neutral	0.01
NPHS1	O60500-1.1	V362L	Neutral	0.002
NPHS1	O60500-1.1	V362M	Neutral	0.001
NPHS1	O60500-1.1	V362N	Neutral	0.002
NPHS1	O60500-1.1	V362P	Neutral	0.001
NPHS1	O60500-1.1	V362Q	Neutral	0.002
NPHS1	O60500-1.1	V362R	Neutral	0.009
NPHS1	O60500-1.1	V362S	Neutral	0.003
NPHS1	O60500-1.1	V362T	Neutral	0.002
NPHS1	O60500-1.1	V362W	Neutral	0.002
NPHS1	O60500-1.1	V362Y	Neutral	0.001
NPHS1	O60500-1.1	S363A	Neutral	0.142
NPHS1	O60500-1.1	S363C	Neutral	0.193
NPHS1	O60500-1.1	S363D	Neutral	0.208
NPHS1	O60500-1.1	S363E	Neutral	0.248
NPHS1	O60500-1.1	S363F	Pathogenic	0.629
NPHS1	O60500-1.1	S363G	Neutral	0.099
NPHS1	O60500-1.1	S363H	Neutral	0.126
NPHS1	O60500-1.1	S363I	Pathogenic	0.572
NPHS1	O60500-1.1	S363K	Pathogenic	0.507
NPHS1	O60500-1.1	S363L	Pathogenic	0.534
NPHS1	O60500-1.1	S363M	Neutral	0.459
NPHS1	O60500-1.1	S363N	Neutral	0.255
NPHS1	O60500-1.1	S363P	Neutral	0.151
NPHS1	O60500-1.1	S363Q	Neutral	0.166
NPHS1	O60500-1.1	S363R	Neutral	0.489
NPHS1	O60500-1.1	S363T	Neutral	0.176
NPHS1	O60500-1.1	S363V	Neutral	0.262
NPHS1	O60500-1.1	S363W	Pathogenic	0.814
NPHS1	O60500-1.1	S363Y	Neutral	0.363
NPHS1	O60500-1.1	K364A	Pathogenic	0.947
NPHS1	O60500-1.1	K364C	Pathogenic	0.934
NPHS1	O60500-1.1	K364D	Pathogenic	0.672
NPHS1	O60500-1.1	K364E	Pathogenic	0.784
NPHS1	O60500-1.1	K364F	Pathogenic	0.936
NPHS1	O60500-1.1	K364G	Pathogenic	0.923
NPHS1	O60500-1.1	K364H	Pathogenic	0.806
NPHS1	O60500-1.1	K364I	Pathogenic	0.951
NPHS1	O60500-1.1	K364L	Pathogenic	0.961
NPHS1	O60500-1.1	K364M	Pathogenic	0.949
NPHS1	O60500-1.1	K364N	Pathogenic	0.777
NPHS1	O60500-1.1	K364P	Pathogenic	0.951
NPHS1	O60500-1.1	K364Q	Pathogenic	0.857
NPHS1	O60500-1.1	K364R	Pathogenic	0.707
NPHS1	O60500-1.1	K364S	Pathogenic	0.933
NPHS1	O60500-1.1	K364T	Pathogenic	0.9
NPHS1	O60500-1.1	K364V	Pathogenic	0.95
NPHS1	O60500-1.1	K364W	Pathogenic	0.983
NPHS1	O60500-1.1	K364Y	Pathogenic	0.88
NPHS1	O60500-1.1	S365A	Pathogenic	0.749
NPHS1	O60500-1.1	S365C	Pathogenic	0.812
NPHS1	O60500-1.1	S365D	Pathogenic	0.826
NPHS1	O60500-1.1	S365E	Pathogenic	0.856
NPHS1	O60500-1.1	S365F	Pathogenic	0.968
NPHS1	O60500-1.1	S365G	Pathogenic	0.665
NPHS1	O60500-1.1	S365H	Pathogenic	0.722
NPHS1	O60500-1.1	S365I	Pathogenic	0.96
NPHS1	O60500-1.1	S365K	Pathogenic	0.949
NPHS1	O60500-1.1	S365L	Pathogenic	0.954
NPHS1	O60500-1.1	S365M	Pathogenic	0.939
NPHS1	O60500-1.1	S365N	Pathogenic	0.861
NPHS1	O60500-1.1	S365P	Pathogenic	0.762
NPHS1	O60500-1.1	S365Q	Pathogenic	0.783
NPHS1	O60500-1.1	S365R	Pathogenic	0.945
NPHS1	O60500-1.1	S365T	Pathogenic	0.794
NPHS1	O60500-1.1	S365V	Pathogenic	0.866
NPHS1	O60500-1.1	S365W	Pathogenic	0.988
NPHS1	O60500-1.1	S365Y	Pathogenic	0.911
NPHS1	O60500-1.1	S366A	Pathogenic	0.984
NPHS1	O60500-1.1	S366C	Pathogenic	0.989
NPHS1	O60500-1.1	S366D	Pathogenic	0.99
NPHS1	O60500-1.1	S366E	Pathogenic	0.992
NPHS1	O60500-1.1	S366F	Pathogenic	0.998
NPHS1	O60500-1.1	S366G	Pathogenic	0.976
NPHS1	O60500-1.1	S366H	Pathogenic	0.981
NPHS1	O60500-1.1	S366I	Pathogenic	0.998
NPHS1	O60500-1.1	S366K	Pathogenic	0.997
NPHS1	O60500-1.1	S366L	Pathogenic	0.998
NPHS1	O60500-1.1	S366M	Pathogenic	0.997
NPHS1	O60500-1.1	S366N	Pathogenic	0.992
NPHS1	O60500-1.1	S366P	Pathogenic	0.985
NPHS1	O60500-1.1	S366Q	Pathogenic	0.986
NPHS1	O60500-1.1	S366R	Pathogenic	0.997
NPHS1	O60500-1.1	S366T	Pathogenic	0.987
NPHS1	O60500-1.1	S366V	Pathogenic	0.992
NPHS1	O60500-1.1	S366W	Pathogenic	0.999
NPHS1	O60500-1.1	S366Y	Pathogenic	0.995
NPHS1	O60500-1.1	R367A	Pathogenic	0.966
NPHS1	O60500-1.1	R367C	Pathogenic	0.957
NPHS1	O60500-1.1	R367D	Pathogenic	0.685
NPHS1	O60500-1.1	R367E	Pathogenic	0.794
NPHS1	O60500-1.1	R367F	Pathogenic	0.959
NPHS1	O60500-1.1	R367G	Pathogenic	0.95
NPHS1	O60500-1.1	R367H	Pathogenic	0.907
NPHS1	O60500-1.1	R367I	Pathogenic	0.969
NPHS1	O60500-1.1	R367K	Pathogenic	0.733
NPHS1	O60500-1.1	R367L	Pathogenic	0.975
NPHS1	O60500-1.1	R367M	Pathogenic	0.967
NPHS1	O60500-1.1	R367N	Pathogenic	0.847
NPHS1	O60500-1.1	R367P	Pathogenic	0.953
NPHS1	O60500-1.1	R367Q	Pathogenic	0.905
NPHS1	O60500-1.1	R367S	Pathogenic	0.937
NPHS1	O60500-1.1	R367T	Pathogenic	0.935
NPHS1	O60500-1.1	R367V	Pathogenic	0.953
NPHS1	O60500-1.1	R367W	Pathogenic	0.98
NPHS1	O60500-1.1	R367Y	Pathogenic	0.898
NPHS1	O60500-1.1	P368A	Pathogenic	0.972
NPHS1	O60500-1.1	P368C	Pathogenic	0.888
NPHS1	O60500-1.1	P368D	Pathogenic	0.99
NPHS1	O60500-1.1	P368E	Pathogenic	0.992
NPHS1	O60500-1.1	P368F	Pathogenic	0.979
NPHS1	O60500-1.1	P368G	Pathogenic	0.983
NPHS1	O60500-1.1	P368H	Pathogenic	0.971
NPHS1	O60500-1.1	P368I	Pathogenic	0.982
NPHS1	O60500-1.1	P368K	Pathogenic	0.997
NPHS1	O60500-1.1	P368L	Pathogenic	0.979
NPHS1	O60500-1.1	P368M	Pathogenic	0.972
NPHS1	O60500-1.1	P368N	Pathogenic	0.983
NPHS1	O60500-1.1	P368Q	Pathogenic	0.987
NPHS1	O60500-1.1	P368R	Pathogenic	0.997
NPHS1	O60500-1.1	P368S	Pathogenic	0.98
NPHS1	O60500-1.1	P368T	Pathogenic	0.958
NPHS1	O60500-1.1	P368V	Pathogenic	0.956
NPHS1	O60500-1.1	P368W	Pathogenic	0.994
NPHS1	O60500-1.1	P368Y	Pathogenic	0.959
NPHS1	O60500-1.1	R369A	Pathogenic	0.918
NPHS1	O60500-1.1	R369C	Pathogenic	0.898
NPHS1	O60500-1.1	R369D	Neutral	0.462
NPHS1	O60500-1.1	R369E	Pathogenic	0.603
NPHS1	O60500-1.1	R369F	Pathogenic	0.902
NPHS1	O60500-1.1	R369G	Pathogenic	0.882
NPHS1	O60500-1.1	R369H	Pathogenic	0.794
NPHS1	O60500-1.1	R369I	Pathogenic	0.924
NPHS1	O60500-1.1	R369K	Pathogenic	0.52
NPHS1	O60500-1.1	R369L	Pathogenic	0.94
NPHS1	O60500-1.1	R369M	Pathogenic	0.92
NPHS1	O60500-1.1	R369N	Pathogenic	0.685
NPHS1	O60500-1.1	R369P	Pathogenic	0.889
NPHS1	O60500-1.1	R369Q	Pathogenic	0.789
NPHS1	O60500-1.1	R369S	Pathogenic	0.854
NPHS1	O60500-1.1	R369T	Pathogenic	0.849
NPHS1	O60500-1.1	R369V	Pathogenic	0.888
NPHS1	O60500-1.1	R369W	Pathogenic	0.95
NPHS1	O60500-1.1	R369Y	Pathogenic	0.776
NPHS1	O60500-1.1	V370A	Pathogenic	0.992
NPHS1	O60500-1.1	V370C	Pathogenic	0.953
NPHS1	O60500-1.1	V370D	Pathogenic	0.991
NPHS1	O60500-1.1	V370E	Pathogenic	0.991
NPHS1	O60500-1.1	V370F	Pathogenic	0.978
NPHS1	O60500-1.1	V370G	Pathogenic	0.99
NPHS1	O60500-1.1	V370H	Pathogenic	0.966
NPHS1	O60500-1.1	V370I	Pathogenic	0.994
NPHS1	O60500-1.1	V370K	Pathogenic	0.997
NPHS1	O60500-1.1	V370L	Pathogenic	0.985
NPHS1	O60500-1.1	V370M	Pathogenic	0.97
NPHS1	O60500-1.1	V370N	Pathogenic	0.987
NPHS1	O60500-1.1	V370P	Pathogenic	0.949
NPHS1	O60500-1.1	V370Q	Pathogenic	0.985
NPHS1	O60500-1.1	V370R	Pathogenic	0.997
NPHS1	O60500-1.1	V370S	Pathogenic	0.988
NPHS1	O60500-1.1	V370T	Pathogenic	0.987
NPHS1	O60500-1.1	V370W	Pathogenic	0.987
NPHS1	O60500-1.1	V370Y	Pathogenic	0.969
NPHS1	O60500-1.1	L371A	Pathogenic	0.56
NPHS1	O60500-1.1	L371C	Neutral	0.23
NPHS1	O60500-1.1	L371D	Pathogenic	0.52
NPHS1	O60500-1.1	L371E	Neutral	0.464
NPHS1	O60500-1.1	L371F	Neutral	0.084
NPHS1	O60500-1.1	L371G	Neutral	0.488
NPHS1	O60500-1.1	L371H	Neutral	0.182
NPHS1	O60500-1.1	L371I	Neutral	0.139
NPHS1	O60500-1.1	L371K	Pathogenic	0.665
NPHS1	O60500-1.1	L371M	Neutral	0.217
NPHS1	O60500-1.1	L371N	Pathogenic	0.528
NPHS1	O60500-1.1	L371P	Neutral	0.153
NPHS1	O60500-1.1	L371Q	Neutral	0.382
NPHS1	O60500-1.1	L371R	Pathogenic	0.734
NPHS1	O60500-1.1	L371S	Pathogenic	0.553
NPHS1	O60500-1.1	L371T	Neutral	0.427
NPHS1	O60500-1.1	L371V	Neutral	0.23
NPHS1	O60500-1.1	L371W	Neutral	0.137
NPHS1	O60500-1.1	L371Y	Neutral	0.158
NPHS1	O60500-1.1	L372A	Pathogenic	0.945
NPHS1	O60500-1.1	L372C	Pathogenic	0.801
NPHS1	O60500-1.1	L372D	Pathogenic	0.936
NPHS1	O60500-1.1	L372E	Pathogenic	0.921
NPHS1	O60500-1.1	L372F	Pathogenic	0.553
NPHS1	O60500-1.1	L372G	Pathogenic	0.928
NPHS1	O60500-1.1	L372H	Pathogenic	0.75
NPHS1	O60500-1.1	L372I	Pathogenic	0.685
NPHS1	O60500-1.1	L372K	Pathogenic	0.964
NPHS1	O60500-1.1	L372M	Pathogenic	0.789
NPHS1	O60500-1.1	L372N	Pathogenic	0.938
NPHS1	O60500-1.1	L372P	Pathogenic	0.709
NPHS1	O60500-1.1	L372Q	Pathogenic	0.893
NPHS1	O60500-1.1	L372R	Pathogenic	0.974
NPHS1	O60500-1.1	L372S	Pathogenic	0.943
NPHS1	O60500-1.1	L372T	Pathogenic	0.909
NPHS1	O60500-1.1	L372V	Pathogenic	0.801
NPHS1	O60500-1.1	L372W	Pathogenic	0.682
NPHS1	O60500-1.1	L372Y	Pathogenic	0.717
NPHS1	O60500-1.1	R373A	Pathogenic	0.997
NPHS1	O60500-1.1	R373C	Pathogenic	0.996
NPHS1	O60500-1.1	R373D	Pathogenic	0.962
NPHS1	O60500-1.1	R373E	Pathogenic	0.978
NPHS1	O60500-1.1	R373F	Pathogenic	0.996
NPHS1	O60500-1.1	R373G	Pathogenic	0.995
NPHS1	O60500-1.1	R373H	Pathogenic	0.991
NPHS1	O60500-1.1	R373I	Pathogenic	0.997
NPHS1	O60500-1.1	R373K	Pathogenic	0.969
NPHS1	O60500-1.1	R373L	Pathogenic	0.998
NPHS1	O60500-1.1	R373M	Pathogenic	0.997
NPHS1	O60500-1.1	R373N	Pathogenic	0.985
NPHS1	O60500-1.1	R373P	Pathogenic	0.996
NPHS1	O60500-1.1	R373Q	Pathogenic	0.991
NPHS1	O60500-1.1	R373S	Pathogenic	0.994
NPHS1	O60500-1.1	R373T	Pathogenic	0.994
NPHS1	O60500-1.1	R373V	Pathogenic	0.996
NPHS1	O60500-1.1	R373W	Pathogenic	0.998
NPHS1	O60500-1.1	R373Y	Pathogenic	0.99
NPHS1	O60500-1.1	W374A	Pathogenic	1.0
NPHS1	O60500-1.1	W374C	Pathogenic	1.0
NPHS1	O60500-1.1	W374D	Pathogenic	1.0
NPHS1	O60500-1.1	W374E	Pathogenic	1.0
NPHS1	O60500-1.1	W374F	Pathogenic	1.0
NPHS1	O60500-1.1	W374G	Pathogenic	1.0
NPHS1	O60500-1.1	W374H	Pathogenic	1.0
NPHS1	O60500-1.1	W374I	Pathogenic	0.998
NPHS1	O60500-1.1	W374K	Pathogenic	1.0
NPHS1	O60500-1.1	W374L	Pathogenic	0.999
NPHS1	O60500-1.1	W374M	Pathogenic	1.0
NPHS1	O60500-1.1	W374N	Pathogenic	1.0
NPHS1	O60500-1.1	W374P	Pathogenic	1.0
NPHS1	O60500-1.1	W374Q	Pathogenic	1.0
NPHS1	O60500-1.1	W374R	Pathogenic	1.0
NPHS1	O60500-1.1	W374S	Pathogenic	1.0
NPHS1	O60500-1.1	W374T	Pathogenic	1.0
NPHS1	O60500-1.1	W374V	Pathogenic	1.0
NPHS1	O60500-1.1	W374Y	Pathogenic	1.0
NPHS1	O60500-1.1	W375A	Pathogenic	1.0
NPHS1	O60500-1.1	W375C	Pathogenic	1.0
NPHS1	O60500-1.1	W375D	Pathogenic	1.0
NPHS1	O60500-1.1	W375E	Pathogenic	1.0
NPHS1	O60500-1.1	W375F	Pathogenic	1.0
NPHS1	O60500-1.1	W375G	Pathogenic	1.0
NPHS1	O60500-1.1	W375H	Pathogenic	1.0
NPHS1	O60500-1.1	W375I	Pathogenic	0.998
NPHS1	O60500-1.1	W375K	Pathogenic	1.0
NPHS1	O60500-1.1	W375L	Pathogenic	0.999
NPHS1	O60500-1.1	W375M	Pathogenic	1.0
NPHS1	O60500-1.1	W375N	Pathogenic	1.0
NPHS1	O60500-1.1	W375P	Pathogenic	1.0
NPHS1	O60500-1.1	W375Q	Pathogenic	1.0
NPHS1	O60500-1.1	W375R	Pathogenic	1.0
NPHS1	O60500-1.1	W375S	Pathogenic	1.0
NPHS1	O60500-1.1	W375T	Pathogenic	1.0
NPHS1	O60500-1.1	W375V	Pathogenic	1.0
NPHS1	O60500-1.1	W375Y	Pathogenic	1.0
NPHS1	O60500-1.1	L376A	Pathogenic	0.996
NPHS1	O60500-1.1	L376C	Pathogenic	0.983
NPHS1	O60500-1.1	L376D	Pathogenic	0.995
NPHS1	O60500-1.1	L376E	Pathogenic	0.994
NPHS1	O60500-1.1	L376F	Pathogenic	0.947
NPHS1	O60500-1.1	L376G	Pathogenic	0.995
NPHS1	O60500-1.1	L376H	Pathogenic	0.978
NPHS1	O60500-1.1	L376I	Pathogenic	0.969
NPHS1	O60500-1.1	L376K	Pathogenic	0.997
NPHS1	O60500-1.1	L376M	Pathogenic	0.982
NPHS1	O60500-1.1	L376N	Pathogenic	0.995
NPHS1	O60500-1.1	L376P	Pathogenic	0.972
NPHS1	O60500-1.1	L376Q	Pathogenic	0.992
NPHS1	O60500-1.1	L376R	Pathogenic	0.998
NPHS1	O60500-1.1	L376S	Pathogenic	0.996
NPHS1	O60500-1.1	L376T	Pathogenic	0.993
NPHS1	O60500-1.1	L376V	Pathogenic	0.983
NPHS1	O60500-1.1	L376W	Pathogenic	0.969
NPHS1	O60500-1.1	L376Y	Pathogenic	0.973
NPHS1	O60500-1.1	G377A	Pathogenic	0.981
NPHS1	O60500-1.1	G377C	Pathogenic	0.985
NPHS1	O60500-1.1	G377D	Pathogenic	0.992
NPHS1	O60500-1.1	G377E	Pathogenic	0.99
NPHS1	O60500-1.1	G377F	Pathogenic	0.999
NPHS1	O60500-1.1	G377H	Pathogenic	0.984
NPHS1	O60500-1.1	G377I	Pathogenic	0.997
NPHS1	O60500-1.1	G377K	Pathogenic	0.997
NPHS1	O60500-1.1	G377L	Pathogenic	0.997
NPHS1	O60500-1.1	G377M	Pathogenic	0.996
NPHS1	O60500-1.1	G377N	Pathogenic	0.994
NPHS1	O60500-1.1	G377P	Pathogenic	0.987
NPHS1	O60500-1.1	G377Q	Pathogenic	0.984
NPHS1	O60500-1.1	G377R	Pathogenic	0.998
NPHS1	O60500-1.1	G377S	Pathogenic	0.976
NPHS1	O60500-1.1	G377T	Pathogenic	0.976
NPHS1	O60500-1.1	G377V	Pathogenic	0.993
NPHS1	O60500-1.1	G377W	Pathogenic	1.0
NPHS1	O60500-1.1	G377Y	Pathogenic	0.996
NPHS1	O60500-1.1	W378A	Pathogenic	0.973
NPHS1	O60500-1.1	W378C	Pathogenic	0.925
NPHS1	O60500-1.1	W378D	Pathogenic	0.985
NPHS1	O60500-1.1	W378E	Pathogenic	0.982
NPHS1	O60500-1.1	W378F	Pathogenic	0.795
NPHS1	O60500-1.1	W378G	Pathogenic	0.992
NPHS1	O60500-1.1	W378H	Pathogenic	0.954
NPHS1	O60500-1.1	W378I	Neutral	0.499
NPHS1	O60500-1.1	W378K	Pathogenic	0.98
NPHS1	O60500-1.1	W378L	Pathogenic	0.634
NPHS1	O60500-1.1	W378M	Pathogenic	0.838
NPHS1	O60500-1.1	W378N	Pathogenic	0.979
NPHS1	O60500-1.1	W378P	Pathogenic	0.882
NPHS1	O60500-1.1	W378Q	Pathogenic	0.974
NPHS1	O60500-1.1	W378R	Pathogenic	0.974
NPHS1	O60500-1.1	W378S	Pathogenic	0.981
NPHS1	O60500-1.1	W378T	Pathogenic	0.969
NPHS1	O60500-1.1	W378V	Pathogenic	0.789
NPHS1	O60500-1.1	W378Y	Pathogenic	0.945
NPHS1	O60500-1.1	R379A	Pathogenic	0.996
NPHS1	O60500-1.1	R379C	Pathogenic	0.994
NPHS1	O60500-1.1	R379D	Pathogenic	0.946
NPHS1	O60500-1.1	R379E	Pathogenic	0.969
NPHS1	O60500-1.1	R379F	Pathogenic	0.995
NPHS1	O60500-1.1	R379G	Pathogenic	0.993
NPHS1	O60500-1.1	R379H	Pathogenic	0.987
NPHS1	O60500-1.1	R379I	Pathogenic	0.996
NPHS1	O60500-1.1	R379K	Pathogenic	0.957
NPHS1	O60500-1.1	R379L	Pathogenic	0.997
NPHS1	O60500-1.1	R379M	Pathogenic	0.996
NPHS1	O60500-1.1	R379N	Pathogenic	0.978
NPHS1	O60500-1.1	R379P	Pathogenic	0.994
NPHS1	O60500-1.1	R379Q	Pathogenic	0.987
NPHS1	O60500-1.1	R379S	Pathogenic	0.992
NPHS1	O60500-1.1	R379T	Pathogenic	0.991
NPHS1	O60500-1.1	R379V	Pathogenic	0.994
NPHS1	O60500-1.1	R379W	Pathogenic	0.997
NPHS1	O60500-1.1	R379Y	Pathogenic	0.986
NPHS1	O60500-1.1	Q380A	Pathogenic	0.857
NPHS1	O60500-1.1	Q380C	Pathogenic	0.825
NPHS1	O60500-1.1	Q380D	Pathogenic	0.84
NPHS1	O60500-1.1	Q380E	Pathogenic	0.863
NPHS1	O60500-1.1	Q380F	Pathogenic	0.93
NPHS1	O60500-1.1	Q380G	Pathogenic	0.8
NPHS1	O60500-1.1	Q380H	Pathogenic	0.714
NPHS1	O60500-1.1	Q380I	Pathogenic	0.913
NPHS1	O60500-1.1	Q380K	Pathogenic	0.912
NPHS1	O60500-1.1	Q380L	Pathogenic	0.93
NPHS1	O60500-1.1	Q380M	Pathogenic	0.937
NPHS1	O60500-1.1	Q380N	Pathogenic	0.784
NPHS1	O60500-1.1	Q380P	Pathogenic	0.866
NPHS1	O60500-1.1	Q380R	Pathogenic	0.935
NPHS1	O60500-1.1	Q380S	Pathogenic	0.823
NPHS1	O60500-1.1	Q380T	Pathogenic	0.751
NPHS1	O60500-1.1	Q380V	Pathogenic	0.864
NPHS1	O60500-1.1	Q380W	Pathogenic	0.987
NPHS1	O60500-1.1	Q380Y	Pathogenic	0.908
NPHS1	O60500-1.1	L381A	Pathogenic	0.996
NPHS1	O60500-1.1	L381C	Pathogenic	0.983
NPHS1	O60500-1.1	L381D	Pathogenic	0.995
NPHS1	O60500-1.1	L381E	Pathogenic	0.994
NPHS1	O60500-1.1	L381F	Pathogenic	0.947
NPHS1	O60500-1.1	L381G	Pathogenic	0.995
NPHS1	O60500-1.1	L381H	Pathogenic	0.978
NPHS1	O60500-1.1	L381I	Pathogenic	0.969
NPHS1	O60500-1.1	L381K	Pathogenic	0.997
NPHS1	O60500-1.1	L381M	Pathogenic	0.982
NPHS1	O60500-1.1	L381N	Pathogenic	0.995
NPHS1	O60500-1.1	L381P	Pathogenic	0.972
NPHS1	O60500-1.1	L381Q	Pathogenic	0.992
NPHS1	O60500-1.1	L381R	Pathogenic	0.998
NPHS1	O60500-1.1	L381S	Pathogenic	0.996
NPHS1	O60500-1.1	L381T	Pathogenic	0.993
NPHS1	O60500-1.1	L381V	Pathogenic	0.983
NPHS1	O60500-1.1	L381W	Pathogenic	0.969
NPHS1	O60500-1.1	L381Y	Pathogenic	0.973
NPHS1	O60500-1.1	L382A	Neutral	0.02
NPHS1	O60500-1.1	L382C	Neutral	0.005
NPHS1	O60500-1.1	L382D	Neutral	0.017
NPHS1	O60500-1.1	L382E	Neutral	0.014
NPHS1	O60500-1.1	L382F	Neutral	0.001
NPHS1	O60500-1.1	L382G	Neutral	0.015
NPHS1	O60500-1.1	L382H	Neutral	0.004
NPHS1	O60500-1.1	L382I	Neutral	0.003
NPHS1	O60500-1.1	L382K	Neutral	0.031
NPHS1	O60500-1.1	L382M	Neutral	0.004
NPHS1	O60500-1.1	L382N	Neutral	0.018
NPHS1	O60500-1.1	L382P	Neutral	0.003
NPHS1	O60500-1.1	L382Q	Neutral	0.01
NPHS1	O60500-1.1	L382R	Neutral	0.042
NPHS1	O60500-1.1	L382S	Neutral	0.019
NPHS1	O60500-1.1	L382T	Neutral	0.012
NPHS1	O60500-1.1	L382V	Neutral	0.005
NPHS1	O60500-1.1	L382W	Neutral	0.003
NPHS1	O60500-1.1	L382Y	Neutral	0.003
NPHS1	O60500-1.1	P383A	Neutral	0.099
NPHS1	O60500-1.1	P383C	Neutral	0.025
NPHS1	O60500-1.1	P383D	Neutral	0.246
NPHS1	O60500-1.1	P383E	Neutral	0.291
NPHS1	O60500-1.1	P383F	Neutral	0.13
NPHS1	O60500-1.1	P383G	Neutral	0.155
NPHS1	O60500-1.1	P383H	Neutral	0.097
NPHS1	O60500-1.1	P383I	Neutral	0.149
NPHS1	O60500-1.1	P383K	Pathogenic	0.561
NPHS1	O60500-1.1	P383L	Neutral	0.131
NPHS1	O60500-1.1	P383M	Neutral	0.1
NPHS1	O60500-1.1	P383N	Neutral	0.161
NPHS1	O60500-1.1	P383Q	Neutral	0.198
NPHS1	O60500-1.1	P383R	Pathogenic	0.544
NPHS1	O60500-1.1	P383S	Neutral	0.138
NPHS1	O60500-1.1	P383T	Neutral	0.069
NPHS1	O60500-1.1	P383V	Neutral	0.065
NPHS1	O60500-1.1	P383W	Neutral	0.365
NPHS1	O60500-1.1	P383Y	Neutral	0.069
NPHS1	O60500-1.1	M384A	Pathogenic	0.768
NPHS1	O60500-1.1	M384C	Neutral	0.437
NPHS1	O60500-1.1	M384D	Pathogenic	0.808
NPHS1	O60500-1.1	M384E	Pathogenic	0.771
NPHS1	O60500-1.1	M384F	Neutral	0.492
NPHS1	O60500-1.1	M384G	Pathogenic	0.787
NPHS1	O60500-1.1	M384H	Neutral	0.464
NPHS1	O60500-1.1	M384I	Pathogenic	0.532
NPHS1	O60500-1.1	M384K	Pathogenic	0.885
NPHS1	O60500-1.1	M384L	Pathogenic	0.593
NPHS1	O60500-1.1	M384N	Pathogenic	0.813
NPHS1	O60500-1.1	M384P	Neutral	0.412
NPHS1	O60500-1.1	M384Q	Pathogenic	0.781
NPHS1	O60500-1.1	M384R	Pathogenic	0.915
NPHS1	O60500-1.1	M384S	Pathogenic	0.828
NPHS1	O60500-1.1	M384T	Pathogenic	0.66
NPHS1	O60500-1.1	M384V	Neutral	0.437
NPHS1	O60500-1.1	M384W	Pathogenic	0.714
NPHS1	O60500-1.1	M384Y	Neutral	0.328
NPHS1	O60500-1.1	E385A	Pathogenic	0.571
NPHS1	O60500-1.1	E385C	Neutral	0.412
NPHS1	O60500-1.1	E385D	Neutral	0.428
NPHS1	O60500-1.1	E385F	Pathogenic	0.788
NPHS1	O60500-1.1	E385G	Neutral	0.47
NPHS1	O60500-1.1	E385H	Neutral	0.412
NPHS1	O60500-1.1	E385I	Pathogenic	0.746
NPHS1	O60500-1.1	E385K	Neutral	0.456
NPHS1	O60500-1.1	E385L	Pathogenic	0.716
NPHS1	O60500-1.1	E385M	Pathogenic	0.651
NPHS1	O60500-1.1	E385N	Neutral	0.206
NPHS1	O60500-1.1	E385P	Pathogenic	0.588
NPHS1	O60500-1.1	E385Q	Neutral	0.457
NPHS1	O60500-1.1	E385R	Neutral	0.439
NPHS1	O60500-1.1	E385S	Pathogenic	0.508
NPHS1	O60500-1.1	E385T	Neutral	0.401
NPHS1	O60500-1.1	E385V	Pathogenic	0.585
NPHS1	O60500-1.1	E385W	Pathogenic	0.935
NPHS1	O60500-1.1	E385Y	Pathogenic	0.651
NPHS1	O60500-1.1	E386A	Pathogenic	0.718
NPHS1	O60500-1.1	E386C	Pathogenic	0.573
NPHS1	O60500-1.1	E386D	Pathogenic	0.588
NPHS1	O60500-1.1	E386F	Pathogenic	0.877
NPHS1	O60500-1.1	E386G	Pathogenic	0.629
NPHS1	O60500-1.1	E386H	Pathogenic	0.573
NPHS1	O60500-1.1	E386I	Pathogenic	0.849
NPHS1	O60500-1.1	E386K	Pathogenic	0.616
NPHS1	O60500-1.1	E386L	Pathogenic	0.828
NPHS1	O60500-1.1	E386M	Pathogenic	0.781
NPHS1	O60500-1.1	E386N	Neutral	0.331
NPHS1	O60500-1.1	E386P	Pathogenic	0.732
NPHS1	O60500-1.1	E386Q	Pathogenic	0.617
NPHS1	O60500-1.1	E386R	Pathogenic	0.6
NPHS1	O60500-1.1	E386S	Pathogenic	0.664
NPHS1	O60500-1.1	E386T	Pathogenic	0.561
NPHS1	O60500-1.1	E386V	Pathogenic	0.73
NPHS1	O60500-1.1	E386W	Pathogenic	0.965
NPHS1	O60500-1.1	E386Y	Pathogenic	0.781
NPHS1	O60500-1.1	T387A	Pathogenic	0.852
NPHS1	O60500-1.1	T387C	Pathogenic	0.871
NPHS1	O60500-1.1	T387D	Pathogenic	0.903
NPHS1	O60500-1.1	T387E	Pathogenic	0.914
NPHS1	O60500-1.1	T387F	Pathogenic	0.972
NPHS1	O60500-1.1	T387G	Pathogenic	0.846
NPHS1	O60500-1.1	T387H	Pathogenic	0.738
NPHS1	O60500-1.1	T387I	Pathogenic	0.976
NPHS1	O60500-1.1	T387K	Pathogenic	0.971
NPHS1	O60500-1.1	T387L	Pathogenic	0.972
NPHS1	O60500-1.1	T387M	Pathogenic	0.945
NPHS1	O60500-1.1	T387N	Pathogenic	0.917
NPHS1	O60500-1.1	T387P	Pathogenic	0.805
NPHS1	O60500-1.1	T387Q	Pathogenic	0.866
NPHS1	O60500-1.1	T387R	Pathogenic	0.979
NPHS1	O60500-1.1	T387S	Pathogenic	0.914
NPHS1	O60500-1.1	T387V	Pathogenic	0.941
NPHS1	O60500-1.1	T387W	Pathogenic	0.992
NPHS1	O60500-1.1	T387Y	Pathogenic	0.92
NPHS1	O60500-1.1	V388A	Pathogenic	0.724
NPHS1	O60500-1.1	V388C	Neutral	0.292
NPHS1	O60500-1.1	V388D	Pathogenic	0.691
NPHS1	O60500-1.1	V388E	Pathogenic	0.683
NPHS1	O60500-1.1	V388F	Neutral	0.469
NPHS1	O60500-1.1	V388G	Pathogenic	0.662
NPHS1	O60500-1.1	V388H	Neutral	0.363
NPHS1	O60500-1.1	V388I	Pathogenic	0.775
NPHS1	O60500-1.1	V388K	Pathogenic	0.871
NPHS1	O60500-1.1	V388L	Pathogenic	0.57
NPHS1	O60500-1.1	V388M	Neutral	0.398
NPHS1	O60500-1.1	V388N	Pathogenic	0.607
NPHS1	O60500-1.1	V388P	Neutral	0.271
NPHS1	O60500-1.1	V388Q	Pathogenic	0.566
NPHS1	O60500-1.1	V388R	Pathogenic	0.863
NPHS1	O60500-1.1	V388S	Pathogenic	0.631
NPHS1	O60500-1.1	V388T	Pathogenic	0.605
NPHS1	O60500-1.1	V388W	Pathogenic	0.604
NPHS1	O60500-1.1	V388Y	Neutral	0.389
NPHS1	O60500-1.1	M389A	Pathogenic	0.928
NPHS1	O60500-1.1	M389C	Pathogenic	0.752
NPHS1	O60500-1.1	M389D	Pathogenic	0.942
NPHS1	O60500-1.1	M389E	Pathogenic	0.929
NPHS1	O60500-1.1	M389F	Pathogenic	0.79
NPHS1	O60500-1.1	M389G	Pathogenic	0.935
NPHS1	O60500-1.1	M389H	Pathogenic	0.771
NPHS1	O60500-1.1	M389I	Pathogenic	0.816
NPHS1	O60500-1.1	M389K	Pathogenic	0.968
NPHS1	O60500-1.1	M389L	Pathogenic	0.85
NPHS1	O60500-1.1	M389N	Pathogenic	0.944
NPHS1	O60500-1.1	M389P	Pathogenic	0.732
NPHS1	O60500-1.1	M389Q	Pathogenic	0.933
NPHS1	O60500-1.1	M389R	Pathogenic	0.977
NPHS1	O60500-1.1	M389S	Pathogenic	0.949
NPHS1	O60500-1.1	M389T	Pathogenic	0.883
NPHS1	O60500-1.1	M389V	Pathogenic	0.752
NPHS1	O60500-1.1	M389W	Pathogenic	0.907
NPHS1	O60500-1.1	M389Y	Pathogenic	0.655
NPHS1	O60500-1.1	D390A	Pathogenic	0.756
NPHS1	O60500-1.1	D390C	Pathogenic	0.784
NPHS1	O60500-1.1	D390E	Pathogenic	0.765
NPHS1	O60500-1.1	D390F	Pathogenic	0.968
NPHS1	O60500-1.1	D390G	Pathogenic	0.821
NPHS1	O60500-1.1	D390H	Pathogenic	0.793
NPHS1	O60500-1.1	D390I	Pathogenic	0.96
NPHS1	O60500-1.1	D390K	Pathogenic	0.675
NPHS1	O60500-1.1	D390L	Pathogenic	0.932
NPHS1	O60500-1.1	D390M	Pathogenic	0.911
NPHS1	O60500-1.1	D390N	Pathogenic	0.63
NPHS1	O60500-1.1	D390P	Pathogenic	0.832
NPHS1	O60500-1.1	D390Q	Pathogenic	0.755
NPHS1	O60500-1.1	D390R	Pathogenic	0.659
NPHS1	O60500-1.1	D390S	Pathogenic	0.782
NPHS1	O60500-1.1	D390T	Pathogenic	0.718
NPHS1	O60500-1.1	D390V	Pathogenic	0.864
NPHS1	O60500-1.1	D390W	Pathogenic	0.987
NPHS1	O60500-1.1	D390Y	Pathogenic	0.91
NPHS1	O60500-1.1	G391A	Pathogenic	0.63
NPHS1	O60500-1.1	G391C	Pathogenic	0.687
NPHS1	O60500-1.1	G391D	Pathogenic	0.8
NPHS1	O60500-1.1	G391E	Pathogenic	0.771
NPHS1	O60500-1.1	G391F	Pathogenic	0.959
NPHS1	O60500-1.1	G391H	Pathogenic	0.663
NPHS1	O60500-1.1	G391I	Pathogenic	0.925
NPHS1	O60500-1.1	G391K	Pathogenic	0.913
NPHS1	O60500-1.1	G391L	Pathogenic	0.913
NPHS1	O60500-1.1	G391M	Pathogenic	0.886
NPHS1	O60500-1.1	G391N	Pathogenic	0.839
NPHS1	O60500-1.1	G391P	Pathogenic	0.708
NPHS1	O60500-1.1	G391Q	Pathogenic	0.671
NPHS1	O60500-1.1	G391R	Pathogenic	0.936
NPHS1	O60500-1.1	G391S	Pathogenic	0.567
NPHS1	O60500-1.1	G391T	Pathogenic	0.567
NPHS1	O60500-1.1	G391V	Pathogenic	0.83
NPHS1	O60500-1.1	G391W	Pathogenic	0.993
NPHS1	O60500-1.1	G391Y	Pathogenic	0.886
NPHS1	O60500-1.1	L392A	Neutral	0.404
NPHS1	O60500-1.1	L392C	Neutral	0.137
NPHS1	O60500-1.1	L392D	Neutral	0.366
NPHS1	O60500-1.1	L392E	Neutral	0.316
NPHS1	O60500-1.1	L392F	Neutral	0.047
NPHS1	O60500-1.1	L392G	Neutral	0.336
NPHS1	O60500-1.1	L392H	Neutral	0.106
NPHS1	O60500-1.1	L392I	Neutral	0.079
NPHS1	O60500-1.1	L392K	Pathogenic	0.514
NPHS1	O60500-1.1	L392M	Neutral	0.129
NPHS1	O60500-1.1	L392N	Neutral	0.373
NPHS1	O60500-1.1	L392P	Neutral	0.088
NPHS1	O60500-1.1	L392Q	Neutral	0.247
NPHS1	O60500-1.1	L392R	Pathogenic	0.595
NPHS1	O60500-1.1	L392S	Neutral	0.397
NPHS1	O60500-1.1	L392T	Neutral	0.284
NPHS1	O60500-1.1	L392V	Neutral	0.137
NPHS1	O60500-1.1	L392W	Neutral	0.078
NPHS1	O60500-1.1	L392Y	Neutral	0.091
NPHS1	O60500-1.1	H393A	Pathogenic	0.953
NPHS1	O60500-1.1	H393C	Pathogenic	0.96
NPHS1	O60500-1.1	H393D	Pathogenic	0.981
NPHS1	O60500-1.1	H393E	Pathogenic	0.976
NPHS1	O60500-1.1	H393F	Pathogenic	0.992
NPHS1	O60500-1.1	H393G	Pathogenic	0.968
NPHS1	O60500-1.1	H393I	Pathogenic	0.978
NPHS1	O60500-1.1	H393K	Pathogenic	0.982
NPHS1	O60500-1.1	H393L	Pathogenic	0.974
NPHS1	O60500-1.1	H393M	Pathogenic	0.965
NPHS1	O60500-1.1	H393N	Pathogenic	0.987
NPHS1	O60500-1.1	H393P	Pathogenic	0.956
NPHS1	O60500-1.1	H393Q	Pathogenic	0.951
NPHS1	O60500-1.1	H393R	Pathogenic	0.991
NPHS1	O60500-1.1	H393S	Pathogenic	0.963
NPHS1	O60500-1.1	H393T	Pathogenic	0.911
NPHS1	O60500-1.1	H393V	Pathogenic	0.956
NPHS1	O60500-1.1	H393W	Pathogenic	0.997
NPHS1	O60500-1.1	H393Y	Pathogenic	0.993
NPHS1	O60500-1.1	G394A	Pathogenic	0.953
NPHS1	O60500-1.1	G394C	Pathogenic	0.963
NPHS1	O60500-1.1	G394D	Pathogenic	0.98
NPHS1	O60500-1.1	G394E	Pathogenic	0.976
NPHS1	O60500-1.1	G394F	Pathogenic	0.996
NPHS1	O60500-1.1	G394H	Pathogenic	0.959
NPHS1	O60500-1.1	G394I	Pathogenic	0.993
NPHS1	O60500-1.1	G394K	Pathogenic	0.992
NPHS1	O60500-1.1	G394L	Pathogenic	0.992
NPHS1	O60500-1.1	G394M	Pathogenic	0.989
NPHS1	O60500-1.1	G394N	Pathogenic	0.984
NPHS1	O60500-1.1	G394P	Pathogenic	0.967
NPHS1	O60500-1.1	G394Q	Pathogenic	0.961
NPHS1	O60500-1.1	G394R	Pathogenic	0.994
NPHS1	O60500-1.1	G394S	Pathogenic	0.94
NPHS1	O60500-1.1	G394T	Pathogenic	0.94
NPHS1	O60500-1.1	G394V	Pathogenic	0.983
NPHS1	O60500-1.1	G394W	Pathogenic	0.999
NPHS1	O60500-1.1	G394Y	Pathogenic	0.989
NPHS1	O60500-1.1	G395A	Pathogenic	0.964
NPHS1	O60500-1.1	G395C	Pathogenic	0.972
NPHS1	O60500-1.1	G395D	Pathogenic	0.984
NPHS1	O60500-1.1	G395E	Pathogenic	0.981
NPHS1	O60500-1.1	G395F	Pathogenic	0.997
NPHS1	O60500-1.1	G395H	Pathogenic	0.969
NPHS1	O60500-1.1	G395I	Pathogenic	0.995
NPHS1	O60500-1.1	G395K	Pathogenic	0.994
NPHS1	O60500-1.1	G395L	Pathogenic	0.994
NPHS1	O60500-1.1	G395M	Pathogenic	0.992
NPHS1	O60500-1.1	G395N	Pathogenic	0.988
NPHS1	O60500-1.1	G395P	Pathogenic	0.974
NPHS1	O60500-1.1	G395Q	Pathogenic	0.97
NPHS1	O60500-1.1	G395R	Pathogenic	0.996
NPHS1	O60500-1.1	G395S	Pathogenic	0.954
NPHS1	O60500-1.1	G395T	Pathogenic	0.954
NPHS1	O60500-1.1	G395V	Pathogenic	0.987
NPHS1	O60500-1.1	G395W	Pathogenic	1.0
NPHS1	O60500-1.1	G395Y	Pathogenic	0.992
NPHS1	O60500-1.1	H396A	Neutral	0.188
NPHS1	O60500-1.1	H396C	Neutral	0.212
NPHS1	O60500-1.1	H396D	Neutral	0.365
NPHS1	O60500-1.1	H396E	Neutral	0.315
NPHS1	O60500-1.1	H396F	Pathogenic	0.583
NPHS1	O60500-1.1	H396G	Neutral	0.253
NPHS1	O60500-1.1	H396I	Neutral	0.331
NPHS1	O60500-1.1	H396K	Neutral	0.386
NPHS1	O60500-1.1	H396L	Neutral	0.298
NPHS1	O60500-1.1	H396M	Neutral	0.24
NPHS1	O60500-1.1	H396N	Neutral	0.469
NPHS1	O60500-1.1	H396P	Neutral	0.198
NPHS1	O60500-1.1	H396Q	Neutral	0.18
NPHS1	O60500-1.1	H396R	Pathogenic	0.566
NPHS1	O60500-1.1	H396S	Neutral	0.228
NPHS1	O60500-1.1	H396T	Neutral	0.104
NPHS1	O60500-1.1	H396V	Neutral	0.196
NPHS1	O60500-1.1	H396W	Pathogenic	0.783
NPHS1	O60500-1.1	H396Y	Pathogenic	0.609
NPHS1	O60500-1.1	I397A	Pathogenic	0.965
NPHS1	O60500-1.1	I397C	Pathogenic	0.867
NPHS1	O60500-1.1	I397D	Pathogenic	0.972
NPHS1	O60500-1.1	I397E	Pathogenic	0.95
NPHS1	O60500-1.1	I397F	Pathogenic	0.607
NPHS1	O60500-1.1	I397G	Pathogenic	0.954
NPHS1	O60500-1.1	I397H	Pathogenic	0.829
NPHS1	O60500-1.1	I397K	Pathogenic	0.967
NPHS1	O60500-1.1	I397L	Pathogenic	0.751
NPHS1	O60500-1.1	I397M	Pathogenic	0.802
NPHS1	O60500-1.1	I397N	Pathogenic	0.961
NPHS1	O60500-1.1	I397P	Pathogenic	0.797
NPHS1	O60500-1.1	I397Q	Pathogenic	0.9
NPHS1	O60500-1.1	I397R	Pathogenic	0.976
NPHS1	O60500-1.1	I397S	Pathogenic	0.964
NPHS1	O60500-1.1	I397T	Pathogenic	0.942
NPHS1	O60500-1.1	I397V	Pathogenic	0.935
NPHS1	O60500-1.1	I397W	Pathogenic	0.632
NPHS1	O60500-1.1	I397Y	Pathogenic	0.803
NPHS1	O60500-1.1	S398A	Neutral	0.461
NPHS1	O60500-1.1	S398C	Pathogenic	0.553
NPHS1	O60500-1.1	S398D	Pathogenic	0.576
NPHS1	O60500-1.1	S398E	Pathogenic	0.631
NPHS1	O60500-1.1	S398F	Pathogenic	0.898
NPHS1	O60500-1.1	S398G	Neutral	0.362
NPHS1	O60500-1.1	S398H	Neutral	0.427
NPHS1	O60500-1.1	S398I	Pathogenic	0.874
NPHS1	O60500-1.1	S398K	Pathogenic	0.842
NPHS1	O60500-1.1	S398L	Pathogenic	0.856
NPHS1	O60500-1.1	S398M	Pathogenic	0.815
NPHS1	O60500-1.1	S398N	Pathogenic	0.639
NPHS1	O60500-1.1	S398P	Neutral	0.479
NPHS1	O60500-1.1	S398Q	Pathogenic	0.508
NPHS1	O60500-1.1	S398R	Pathogenic	0.832
NPHS1	O60500-1.1	S398T	Pathogenic	0.525
NPHS1	O60500-1.1	S398V	Pathogenic	0.648
NPHS1	O60500-1.1	S398W	Pathogenic	0.958
NPHS1	O60500-1.1	S398Y	Pathogenic	0.747
NPHS1	O60500-1.1	M399A	Pathogenic	0.998
NPHS1	O60500-1.1	M399C	Pathogenic	0.991
NPHS1	O60500-1.1	M399D	Pathogenic	0.998
NPHS1	O60500-1.1	M399E	Pathogenic	0.998
NPHS1	O60500-1.1	M399F	Pathogenic	0.993
NPHS1	O60500-1.1	M399G	Pathogenic	0.998
NPHS1	O60500-1.1	M399H	Pathogenic	0.992
NPHS1	O60500-1.1	M399I	Pathogenic	0.994
NPHS1	O60500-1.1	M399K	Pathogenic	0.999
NPHS1	O60500-1.1	M399L	Pathogenic	0.995
NPHS1	O60500-1.1	M399N	Pathogenic	0.998
NPHS1	O60500-1.1	M399P	Pathogenic	0.991
NPHS1	O60500-1.1	M399Q	Pathogenic	0.998
NPHS1	O60500-1.1	M399R	Pathogenic	0.999
NPHS1	O60500-1.1	M399S	Pathogenic	0.999
NPHS1	O60500-1.1	M399T	Pathogenic	0.997
NPHS1	O60500-1.1	M399V	Pathogenic	0.991
NPHS1	O60500-1.1	M399W	Pathogenic	0.997
NPHS1	O60500-1.1	M399Y	Pathogenic	0.986
NPHS1	O60500-1.1	S400A	Pathogenic	0.975
NPHS1	O60500-1.1	S400C	Pathogenic	0.983
NPHS1	O60500-1.1	S400D	Pathogenic	0.984
NPHS1	O60500-1.1	S400E	Pathogenic	0.988
NPHS1	O60500-1.1	S400F	Pathogenic	0.998
NPHS1	O60500-1.1	S400G	Pathogenic	0.963
NPHS1	O60500-1.1	S400H	Pathogenic	0.972
NPHS1	O60500-1.1	S400I	Pathogenic	0.997
NPHS1	O60500-1.1	S400K	Pathogenic	0.996
NPHS1	O60500-1.1	S400L	Pathogenic	0.996
NPHS1	O60500-1.1	S400M	Pathogenic	0.995
NPHS1	O60500-1.1	S400N	Pathogenic	0.988
NPHS1	O60500-1.1	S400P	Pathogenic	0.977
NPHS1	O60500-1.1	S400Q	Pathogenic	0.979
NPHS1	O60500-1.1	S400R	Pathogenic	0.996
NPHS1	O60500-1.1	S400T	Pathogenic	0.981
NPHS1	O60500-1.1	S400V	Pathogenic	0.988
NPHS1	O60500-1.1	S400W	Pathogenic	0.999
NPHS1	O60500-1.1	S400Y	Pathogenic	0.993
NPHS1	O60500-1.1	N401A	Pathogenic	0.891
NPHS1	O60500-1.1	N401C	Pathogenic	0.905
NPHS1	O60500-1.1	N401D	Pathogenic	0.836
NPHS1	O60500-1.1	N401E	Pathogenic	0.773
NPHS1	O60500-1.1	N401F	Pathogenic	0.984
NPHS1	O60500-1.1	N401G	Pathogenic	0.947
NPHS1	O60500-1.1	N401H	Pathogenic	0.946
NPHS1	O60500-1.1	N401I	Pathogenic	0.98
NPHS1	O60500-1.1	N401K	Pathogenic	0.914
NPHS1	O60500-1.1	N401L	Pathogenic	0.977
NPHS1	O60500-1.1	N401M	Pathogenic	0.969
NPHS1	O60500-1.1	N401P	Pathogenic	0.897
NPHS1	O60500-1.1	N401Q	Pathogenic	0.865
NPHS1	O60500-1.1	N401R	Pathogenic	0.936
NPHS1	O60500-1.1	N401S	Pathogenic	0.934
NPHS1	O60500-1.1	N401T	Pathogenic	0.901
NPHS1	O60500-1.1	N401V	Pathogenic	0.93
NPHS1	O60500-1.1	N401W	Pathogenic	0.994
NPHS1	O60500-1.1	N401Y	Pathogenic	0.969
NPHS1	O60500-1.1	L402A	Pathogenic	0.954
NPHS1	O60500-1.1	L402C	Pathogenic	0.828
NPHS1	O60500-1.1	L402D	Pathogenic	0.946
NPHS1	O60500-1.1	L402E	Pathogenic	0.933
NPHS1	O60500-1.1	L402F	Pathogenic	0.597
NPHS1	O60500-1.1	L402G	Pathogenic	0.939
NPHS1	O60500-1.1	L402H	Pathogenic	0.782
NPHS1	O60500-1.1	L402I	Pathogenic	0.722
NPHS1	O60500-1.1	L402K	Pathogenic	0.97
NPHS1	O60500-1.1	L402M	Pathogenic	0.818
NPHS1	O60500-1.1	L402N	Pathogenic	0.947
NPHS1	O60500-1.1	L402P	Pathogenic	0.744
NPHS1	O60500-1.1	L402Q	Pathogenic	0.909
NPHS1	O60500-1.1	L402R	Pathogenic	0.978
NPHS1	O60500-1.1	L402S	Pathogenic	0.952
NPHS1	O60500-1.1	L402T	Pathogenic	0.923
NPHS1	O60500-1.1	L402V	Pathogenic	0.828
NPHS1	O60500-1.1	L402W	Pathogenic	0.72
NPHS1	O60500-1.1	L402Y	Pathogenic	0.751
NPHS1	O60500-1.1	T403A	Pathogenic	0.956
NPHS1	O60500-1.1	T403C	Pathogenic	0.962
NPHS1	O60500-1.1	T403D	Pathogenic	0.973
NPHS1	O60500-1.1	T403E	Pathogenic	0.976
NPHS1	O60500-1.1	T403F	Pathogenic	0.992
NPHS1	O60500-1.1	T403G	Pathogenic	0.954
NPHS1	O60500-1.1	T403H	Pathogenic	0.915
NPHS1	O60500-1.1	T403I	Pathogenic	0.993
NPHS1	O60500-1.1	T403K	Pathogenic	0.992
NPHS1	O60500-1.1	T403L	Pathogenic	0.992
NPHS1	O60500-1.1	T403M	Pathogenic	0.985
NPHS1	O60500-1.1	T403N	Pathogenic	0.977
NPHS1	O60500-1.1	T403P	Pathogenic	0.94
NPHS1	O60500-1.1	T403Q	Pathogenic	0.961
NPHS1	O60500-1.1	T403R	Pathogenic	0.994
NPHS1	O60500-1.1	T403S	Pathogenic	0.976
NPHS1	O60500-1.1	T403V	Pathogenic	0.984
NPHS1	O60500-1.1	T403W	Pathogenic	0.998
NPHS1	O60500-1.1	T403Y	Pathogenic	0.978
NPHS1	O60500-1.1	F404A	Pathogenic	0.744
NPHS1	O60500-1.1	F404C	Neutral	0.405
NPHS1	O60500-1.1	F404D	Pathogenic	0.846
NPHS1	O60500-1.1	F404E	Pathogenic	0.747
NPHS1	O60500-1.1	F404G	Pathogenic	0.829
NPHS1	O60500-1.1	F404H	Pathogenic	0.628
NPHS1	O60500-1.1	F404I	Neutral	0.16
NPHS1	O60500-1.1	F404K	Pathogenic	0.73
NPHS1	O60500-1.1	F404L	Neutral	0.175
NPHS1	O60500-1.1	F404M	Neutral	0.299
NPHS1	O60500-1.1	F404N	Pathogenic	0.792
NPHS1	O60500-1.1	F404P	Neutral	0.292
NPHS1	O60500-1.1	F404Q	Pathogenic	0.585
NPHS1	O60500-1.1	F404R	Pathogenic	0.789
NPHS1	O60500-1.1	F404S	Pathogenic	0.808
NPHS1	O60500-1.1	F404T	Pathogenic	0.629
NPHS1	O60500-1.1	F404V	Neutral	0.314
NPHS1	O60500-1.1	F404W	Neutral	0.451
NPHS1	O60500-1.1	F404Y	Pathogenic	0.653
NPHS1	O60500-1.1	L405A	Neutral	0.369
NPHS1	O60500-1.1	L405C	Neutral	0.12
NPHS1	O60500-1.1	L405D	Neutral	0.332
NPHS1	O60500-1.1	L405E	Neutral	0.284
NPHS1	O60500-1.1	L405F	Neutral	0.04
NPHS1	O60500-1.1	L405G	Neutral	0.304
NPHS1	O60500-1.1	L405H	Neutral	0.093
NPHS1	O60500-1.1	L405I	Neutral	0.069
NPHS1	O60500-1.1	L405K	Neutral	0.477
NPHS1	O60500-1.1	L405M	Neutral	0.113
NPHS1	O60500-1.1	L405N	Neutral	0.338
NPHS1	O60500-1.1	L405P	Neutral	0.076
NPHS1	O60500-1.1	L405Q	Neutral	0.22
NPHS1	O60500-1.1	L405R	Pathogenic	0.558
NPHS1	O60500-1.1	L405S	Neutral	0.362
NPHS1	O60500-1.1	L405T	Neutral	0.254
NPHS1	O60500-1.1	L405V	Neutral	0.12
NPHS1	O60500-1.1	L405W	Neutral	0.068
NPHS1	O60500-1.1	L405Y	Neutral	0.079
NPHS1	O60500-1.1	A406C	Neutral	0.335
NPHS1	O60500-1.1	A406D	Neutral	0.318
NPHS1	O60500-1.1	A406E	Neutral	0.466
NPHS1	O60500-1.1	A406F	Pathogenic	0.706
NPHS1	O60500-1.1	A406G	Neutral	0.226
NPHS1	O60500-1.1	A406H	Neutral	0.187
NPHS1	O60500-1.1	A406I	Pathogenic	0.738
NPHS1	O60500-1.1	A406K	Pathogenic	0.731
NPHS1	O60500-1.1	A406L	Pathogenic	0.708
NPHS1	O60500-1.1	A406M	Pathogenic	0.546
NPHS1	O60500-1.1	A406N	Neutral	0.29
NPHS1	O60500-1.1	A406P	Neutral	0.201
NPHS1	O60500-1.1	A406Q	Neutral	0.345
NPHS1	O60500-1.1	A406R	Pathogenic	0.791
NPHS1	O60500-1.1	A406S	Neutral	0.253
NPHS1	O60500-1.1	A406T	Neutral	0.191
NPHS1	O60500-1.1	A406V	Pathogenic	0.529
NPHS1	O60500-1.1	A406W	Pathogenic	0.861
NPHS1	O60500-1.1	A406Y	Neutral	0.446
NPHS1	O60500-1.1	R407A	Pathogenic	0.859
NPHS1	O60500-1.1	R407C	Pathogenic	0.827
NPHS1	O60500-1.1	R407D	Neutral	0.318
NPHS1	O60500-1.1	R407E	Neutral	0.453
NPHS1	O60500-1.1	R407F	Pathogenic	0.833
NPHS1	O60500-1.1	R407G	Pathogenic	0.802
NPHS1	O60500-1.1	R407H	Pathogenic	0.678
NPHS1	O60500-1.1	R407I	Pathogenic	0.869
NPHS1	O60500-1.1	R407K	Neutral	0.371
NPHS1	O60500-1.1	R407L	Pathogenic	0.894
NPHS1	O60500-1.1	R407M	Pathogenic	0.863
NPHS1	O60500-1.1	R407N	Pathogenic	0.543
NPHS1	O60500-1.1	R407P	Pathogenic	0.814
NPHS1	O60500-1.1	R407Q	Pathogenic	0.671
NPHS1	O60500-1.1	R407S	Pathogenic	0.76
NPHS1	O60500-1.1	R407T	Pathogenic	0.754
NPHS1	O60500-1.1	R407V	Pathogenic	0.812
NPHS1	O60500-1.1	R407W	Pathogenic	0.912
NPHS1	O60500-1.1	R407Y	Pathogenic	0.653
NPHS1	O60500-1.1	R408A	Pathogenic	0.998
NPHS1	O60500-1.1	R408C	Pathogenic	0.997
NPHS1	O60500-1.1	R408D	Pathogenic	0.973
NPHS1	O60500-1.1	R408E	Pathogenic	0.985
NPHS1	O60500-1.1	R408F	Pathogenic	0.997
NPHS1	O60500-1.1	R408G	Pathogenic	0.997
NPHS1	O60500-1.1	R408H	Pathogenic	0.994
NPHS1	O60500-1.1	R408I	Pathogenic	0.998
NPHS1	O60500-1.1	R408K	Pathogenic	0.978
NPHS1	O60500-1.1	R408L	Pathogenic	0.998
NPHS1	O60500-1.1	R408M	Pathogenic	0.998
NPHS1	O60500-1.1	R408N	Pathogenic	0.989
NPHS1	O60500-1.1	R408P	Pathogenic	0.997
NPHS1	O60500-1.1	R408Q	Pathogenic	0.994
NPHS1	O60500-1.1	R408S	Pathogenic	0.996
NPHS1	O60500-1.1	R408T	Pathogenic	0.996
NPHS1	O60500-1.1	R408V	Pathogenic	0.997
NPHS1	O60500-1.1	R408W	Pathogenic	0.999
NPHS1	O60500-1.1	R408Y	Pathogenic	0.993
NPHS1	O60500-1.1	E409A	Pathogenic	0.983
NPHS1	O60500-1.1	E409C	Pathogenic	0.968
NPHS1	O60500-1.1	E409D	Pathogenic	0.97
NPHS1	O60500-1.1	E409F	Pathogenic	0.994
NPHS1	O60500-1.1	E409G	Pathogenic	0.975
NPHS1	O60500-1.1	E409H	Pathogenic	0.968
NPHS1	O60500-1.1	E409I	Pathogenic	0.992
NPHS1	O60500-1.1	E409K	Pathogenic	0.973
NPHS1	O60500-1.1	E409L	Pathogenic	0.991
NPHS1	O60500-1.1	E409M	Pathogenic	0.988
NPHS1	O60500-1.1	E409N	Pathogenic	0.918
NPHS1	O60500-1.1	E409P	Pathogenic	0.984
NPHS1	O60500-1.1	E409Q	Pathogenic	0.973
NPHS1	O60500-1.1	E409R	Pathogenic	0.971
NPHS1	O60500-1.1	E409S	Pathogenic	0.978
NPHS1	O60500-1.1	E409T	Pathogenic	0.967
NPHS1	O60500-1.1	E409V	Pathogenic	0.984
NPHS1	O60500-1.1	E409W	Pathogenic	0.998
NPHS1	O60500-1.1	E409Y	Pathogenic	0.988
NPHS1	O60500-1.1	D410A	Pathogenic	0.897
NPHS1	O60500-1.1	D410C	Pathogenic	0.91
NPHS1	O60500-1.1	D410E	Pathogenic	0.901
NPHS1	O60500-1.1	D410F	Pathogenic	0.988
NPHS1	O60500-1.1	D410G	Pathogenic	0.928
NPHS1	O60500-1.1	D410H	Pathogenic	0.914
NPHS1	O60500-1.1	D410I	Pathogenic	0.985
NPHS1	O60500-1.1	D410K	Pathogenic	0.853
NPHS1	O60500-1.1	D410L	Pathogenic	0.975
NPHS1	O60500-1.1	D410M	Pathogenic	0.966
NPHS1	O60500-1.1	D410N	Pathogenic	0.826
NPHS1	O60500-1.1	D410P	Pathogenic	0.933
NPHS1	O60500-1.1	D410Q	Pathogenic	0.896
NPHS1	O60500-1.1	D410R	Pathogenic	0.844
NPHS1	O60500-1.1	D410S	Pathogenic	0.909
NPHS1	O60500-1.1	D410T	Pathogenic	0.877
NPHS1	O60500-1.1	D410V	Pathogenic	0.947
NPHS1	O60500-1.1	D410W	Pathogenic	0.995
NPHS1	O60500-1.1	D410Y	Pathogenic	0.966
NPHS1	O60500-1.1	N411A	Pathogenic	0.987
NPHS1	O60500-1.1	N411C	Pathogenic	0.989
NPHS1	O60500-1.1	N411D	Pathogenic	0.979
NPHS1	O60500-1.1	N411E	Pathogenic	0.969
NPHS1	O60500-1.1	N411F	Pathogenic	0.998
NPHS1	O60500-1.1	N411G	Pathogenic	0.994
NPHS1	O60500-1.1	N411H	Pathogenic	0.994
NPHS1	O60500-1.1	N411I	Pathogenic	0.998
NPHS1	O60500-1.1	N411K	Pathogenic	0.99
NPHS1	O60500-1.1	N411L	Pathogenic	0.997
NPHS1	O60500-1.1	N411M	Pathogenic	0.997
NPHS1	O60500-1.1	N411P	Pathogenic	0.988
NPHS1	O60500-1.1	N411Q	Pathogenic	0.983
NPHS1	O60500-1.1	N411R	Pathogenic	0.993
NPHS1	O60500-1.1	N411S	Pathogenic	0.992
NPHS1	O60500-1.1	N411T	Pathogenic	0.988
NPHS1	O60500-1.1	N411V	Pathogenic	0.992
NPHS1	O60500-1.1	N411W	Pathogenic	0.999
NPHS1	O60500-1.1	N411Y	Pathogenic	0.997
NPHS1	O60500-1.1	G412A	Pathogenic	0.973
NPHS1	O60500-1.1	G412C	Pathogenic	0.979
NPHS1	O60500-1.1	G412D	Pathogenic	0.988
NPHS1	O60500-1.1	G412E	Pathogenic	0.986
NPHS1	O60500-1.1	G412F	Pathogenic	0.998
NPHS1	O60500-1.1	G412H	Pathogenic	0.976
NPHS1	O60500-1.1	G412I	Pathogenic	0.996
NPHS1	O60500-1.1	G412K	Pathogenic	0.996
NPHS1	O60500-1.1	G412L	Pathogenic	0.996
NPHS1	O60500-1.1	G412M	Pathogenic	0.994
NPHS1	O60500-1.1	G412N	Pathogenic	0.991
NPHS1	O60500-1.1	G412P	Pathogenic	0.981
NPHS1	O60500-1.1	G412Q	Pathogenic	0.977
NPHS1	O60500-1.1	G412R	Pathogenic	0.997
NPHS1	O60500-1.1	G412S	Pathogenic	0.965
NPHS1	O60500-1.1	G412T	Pathogenic	0.965
NPHS1	O60500-1.1	G412V	Pathogenic	0.99
NPHS1	O60500-1.1	G412W	Pathogenic	1.0
NPHS1	O60500-1.1	G412Y	Pathogenic	0.994
NPHS1	O60500-1.1	L413A	Pathogenic	0.988
NPHS1	O60500-1.1	L413C	Pathogenic	0.952
NPHS1	O60500-1.1	L413D	Pathogenic	0.986
NPHS1	O60500-1.1	L413E	Pathogenic	0.983
NPHS1	O60500-1.1	L413F	Pathogenic	0.86
NPHS1	O60500-1.1	L413G	Pathogenic	0.984
NPHS1	O60500-1.1	L413H	Pathogenic	0.937
NPHS1	O60500-1.1	L413I	Pathogenic	0.915
NPHS1	O60500-1.1	L413K	Pathogenic	0.993
NPHS1	O60500-1.1	L413M	Pathogenic	0.949
NPHS1	O60500-1.1	L413N	Pathogenic	0.987
NPHS1	O60500-1.1	L413P	Pathogenic	0.923
NPHS1	O60500-1.1	L413Q	Pathogenic	0.976
NPHS1	O60500-1.1	L413R	Pathogenic	0.995
NPHS1	O60500-1.1	L413S	Pathogenic	0.988
NPHS1	O60500-1.1	L413T	Pathogenic	0.98
NPHS1	O60500-1.1	L413V	Pathogenic	0.952
NPHS1	O60500-1.1	L413W	Pathogenic	0.914
NPHS1	O60500-1.1	L413Y	Pathogenic	0.926
NPHS1	O60500-1.1	T414A	Neutral	0.032
NPHS1	O60500-1.1	T414C	Neutral	0.037
NPHS1	O60500-1.1	T414D	Neutral	0.051
NPHS1	O60500-1.1	T414E	Neutral	0.057
NPHS1	O60500-1.1	T414F	Neutral	0.163
NPHS1	O60500-1.1	T414G	Neutral	0.03
NPHS1	O60500-1.1	T414H	Neutral	0.016
NPHS1	O60500-1.1	T414I	Neutral	0.186
NPHS1	O60500-1.1	T414K	Neutral	0.16
NPHS1	O60500-1.1	T414L	Neutral	0.164
NPHS1	O60500-1.1	T414M	Neutral	0.089
NPHS1	O60500-1.1	T414N	Neutral	0.059
NPHS1	O60500-1.1	T414P	Neutral	0.023
NPHS1	O60500-1.1	T414Q	Neutral	0.035
NPHS1	O60500-1.1	T414R	Neutral	0.209
NPHS1	O60500-1.1	T414S	Neutral	0.057
NPHS1	O60500-1.1	T414V	Neutral	0.084
NPHS1	O60500-1.1	T414W	Neutral	0.429
NPHS1	O60500-1.1	T414Y	Neutral	0.061
NPHS1	O60500-1.1	L415A	Pathogenic	0.993
NPHS1	O60500-1.1	L415C	Pathogenic	0.97
NPHS1	O60500-1.1	L415D	Pathogenic	0.992
NPHS1	O60500-1.1	L415E	Pathogenic	0.99
NPHS1	O60500-1.1	L415F	Pathogenic	0.91
NPHS1	O60500-1.1	L415G	Pathogenic	0.991
NPHS1	O60500-1.1	L415H	Pathogenic	0.961
NPHS1	O60500-1.1	L415I	Pathogenic	0.947
NPHS1	O60500-1.1	L415K	Pathogenic	0.995
NPHS1	O60500-1.1	L415M	Pathogenic	0.968
NPHS1	O60500-1.1	L415N	Pathogenic	0.992
NPHS1	O60500-1.1	L415P	Pathogenic	0.952
NPHS1	O60500-1.1	L415Q	Pathogenic	0.986
NPHS1	O60500-1.1	L415R	Pathogenic	0.997
NPHS1	O60500-1.1	L415S	Pathogenic	0.993
NPHS1	O60500-1.1	L415T	Pathogenic	0.988
NPHS1	O60500-1.1	L415V	Pathogenic	0.97
NPHS1	O60500-1.1	L415W	Pathogenic	0.946
NPHS1	O60500-1.1	L415Y	Pathogenic	0.954
NPHS1	O60500-1.1	T416A	Pathogenic	0.956
NPHS1	O60500-1.1	T416C	Pathogenic	0.962
NPHS1	O60500-1.1	T416D	Pathogenic	0.972
NPHS1	O60500-1.1	T416E	Pathogenic	0.976
NPHS1	O60500-1.1	T416F	Pathogenic	0.992
NPHS1	O60500-1.1	T416G	Pathogenic	0.954
NPHS1	O60500-1.1	T416H	Pathogenic	0.913
NPHS1	O60500-1.1	T416I	Pathogenic	0.993
NPHS1	O60500-1.1	T416K	Pathogenic	0.992
NPHS1	O60500-1.1	T416L	Pathogenic	0.992
NPHS1	O60500-1.1	T416M	Pathogenic	0.985
NPHS1	O60500-1.1	T416N	Pathogenic	0.976
NPHS1	O60500-1.1	T416P	Pathogenic	0.939
NPHS1	O60500-1.1	T416Q	Pathogenic	0.96
NPHS1	O60500-1.1	T416R	Pathogenic	0.994
NPHS1	O60500-1.1	T416S	Pathogenic	0.976
NPHS1	O60500-1.1	T416V	Pathogenic	0.984
NPHS1	O60500-1.1	T416W	Pathogenic	0.998
NPHS1	O60500-1.1	T416Y	Pathogenic	0.977
NPHS1	O60500-1.1	C417A	Pathogenic	0.982
NPHS1	O60500-1.1	C417D	Pathogenic	0.983
NPHS1	O60500-1.1	C417E	Pathogenic	0.98
NPHS1	O60500-1.1	C417F	Pathogenic	0.984
NPHS1	O60500-1.1	C417G	Pathogenic	0.976
NPHS1	O60500-1.1	C417H	Pathogenic	0.966
NPHS1	O60500-1.1	C417I	Pathogenic	0.986
NPHS1	O60500-1.1	C417K	Pathogenic	0.996
NPHS1	O60500-1.1	C417L	Pathogenic	0.984
NPHS1	O60500-1.1	C417M	Pathogenic	0.968
NPHS1	O60500-1.1	C417N	Pathogenic	0.981
NPHS1	O60500-1.1	C417P	Pathogenic	0.86
NPHS1	O60500-1.1	C417Q	Pathogenic	0.978
NPHS1	O60500-1.1	C417R	Pathogenic	0.997
NPHS1	O60500-1.1	C417S	Pathogenic	0.981
NPHS1	O60500-1.1	C417T	Pathogenic	0.967
NPHS1	O60500-1.1	C417V	Pathogenic	0.949
NPHS1	O60500-1.1	C417W	Pathogenic	0.996
NPHS1	O60500-1.1	C417Y	Pathogenic	0.955
NPHS1	O60500-1.1	E418A	Pathogenic	0.994
NPHS1	O60500-1.1	E418C	Pathogenic	0.988
NPHS1	O60500-1.1	E418D	Pathogenic	0.989
NPHS1	O60500-1.1	E418F	Pathogenic	0.998
NPHS1	O60500-1.1	E418G	Pathogenic	0.99
NPHS1	O60500-1.1	E418H	Pathogenic	0.988
NPHS1	O60500-1.1	E418I	Pathogenic	0.997
NPHS1	O60500-1.1	E418K	Pathogenic	0.99
NPHS1	O60500-1.1	E418L	Pathogenic	0.997
NPHS1	O60500-1.1	E418M	Pathogenic	0.995
NPHS1	O60500-1.1	E418N	Pathogenic	0.968
NPHS1	O60500-1.1	E418P	Pathogenic	0.994
NPHS1	O60500-1.1	E418Q	Pathogenic	0.99
NPHS1	O60500-1.1	E418R	Pathogenic	0.989
NPHS1	O60500-1.1	E418S	Pathogenic	0.992
NPHS1	O60500-1.1	E418T	Pathogenic	0.987
NPHS1	O60500-1.1	E418V	Pathogenic	0.994
NPHS1	O60500-1.1	E418W	Pathogenic	0.999
NPHS1	O60500-1.1	E418Y	Pathogenic	0.995
NPHS1	O60500-1.1	A419C	Pathogenic	0.985
NPHS1	O60500-1.1	A419D	Pathogenic	0.984
NPHS1	O60500-1.1	A419E	Pathogenic	0.991
NPHS1	O60500-1.1	A419F	Pathogenic	0.997
NPHS1	O60500-1.1	A419G	Pathogenic	0.974
NPHS1	O60500-1.1	A419H	Pathogenic	0.968
NPHS1	O60500-1.1	A419I	Pathogenic	0.997
NPHS1	O60500-1.1	A419K	Pathogenic	0.997
NPHS1	O60500-1.1	A419L	Pathogenic	0.997
NPHS1	O60500-1.1	A419M	Pathogenic	0.994
NPHS1	O60500-1.1	A419N	Pathogenic	0.981
NPHS1	O60500-1.1	A419P	Pathogenic	0.97
NPHS1	O60500-1.1	A419Q	Pathogenic	0.986
NPHS1	O60500-1.1	A419R	Pathogenic	0.998
NPHS1	O60500-1.1	A419S	Pathogenic	0.978
NPHS1	O60500-1.1	A419T	Pathogenic	0.968
NPHS1	O60500-1.1	A419V	Pathogenic	0.993
NPHS1	O60500-1.1	A419W	Pathogenic	0.999
NPHS1	O60500-1.1	A419Y	Pathogenic	0.991
NPHS1	O60500-1.1	F420A	Pathogenic	1.0
NPHS1	O60500-1.1	F420C	Pathogenic	0.998
NPHS1	O60500-1.1	F420D	Pathogenic	1.0
NPHS1	O60500-1.1	F420E	Pathogenic	1.0
NPHS1	O60500-1.1	F420G	Pathogenic	1.0
NPHS1	O60500-1.1	F420H	Pathogenic	0.999
NPHS1	O60500-1.1	F420I	Pathogenic	0.993
NPHS1	O60500-1.1	F420K	Pathogenic	1.0
NPHS1	O60500-1.1	F420L	Pathogenic	0.994
NPHS1	O60500-1.1	F420M	Pathogenic	0.997
NPHS1	O60500-1.1	F420N	Pathogenic	1.0
NPHS1	O60500-1.1	F420P	Pathogenic	0.997
NPHS1	O60500-1.1	F420Q	Pathogenic	0.999
NPHS1	O60500-1.1	F420R	Pathogenic	1.0
NPHS1	O60500-1.1	F420S	Pathogenic	1.0
NPHS1	O60500-1.1	F420T	Pathogenic	0.999
NPHS1	O60500-1.1	F420V	Pathogenic	0.997
NPHS1	O60500-1.1	F420W	Pathogenic	0.998
NPHS1	O60500-1.1	F420Y	Pathogenic	0.999
NPHS1	O60500-1.1	S421A	Pathogenic	0.701
NPHS1	O60500-1.1	S421C	Pathogenic	0.773
NPHS1	O60500-1.1	S421D	Pathogenic	0.789
NPHS1	O60500-1.1	S421E	Pathogenic	0.824
NPHS1	O60500-1.1	S421F	Pathogenic	0.96
NPHS1	O60500-1.1	S421G	Pathogenic	0.609
NPHS1	O60500-1.1	S421H	Pathogenic	0.671
NPHS1	O60500-1.1	S421I	Pathogenic	0.95
NPHS1	O60500-1.1	S421K	Pathogenic	0.936
NPHS1	O60500-1.1	S421L	Pathogenic	0.942
NPHS1	O60500-1.1	S421M	Pathogenic	0.924
NPHS1	O60500-1.1	S421N	Pathogenic	0.83
NPHS1	O60500-1.1	S421P	Pathogenic	0.716
NPHS1	O60500-1.1	S421Q	Pathogenic	0.739
NPHS1	O60500-1.1	S421R	Pathogenic	0.932
NPHS1	O60500-1.1	S421T	Pathogenic	0.752
NPHS1	O60500-1.1	S421V	Pathogenic	0.835
NPHS1	O60500-1.1	S421W	Pathogenic	0.984
NPHS1	O60500-1.1	S421Y	Pathogenic	0.89
NPHS1	O60500-1.1	E422A	Neutral	0.363
NPHS1	O60500-1.1	E422C	Neutral	0.231
NPHS1	O60500-1.1	E422D	Neutral	0.242
NPHS1	O60500-1.1	E422F	Pathogenic	0.614
NPHS1	O60500-1.1	E422G	Neutral	0.275
NPHS1	O60500-1.1	E422H	Neutral	0.231
NPHS1	O60500-1.1	E422I	Pathogenic	0.557
NPHS1	O60500-1.1	E422K	Neutral	0.264
NPHS1	O60500-1.1	E422L	Pathogenic	0.519
NPHS1	O60500-1.1	E422M	Neutral	0.444
NPHS1	O60500-1.1	E422N	Neutral	0.1
NPHS1	O60500-1.1	E422P	Neutral	0.379
NPHS1	O60500-1.1	E422Q	Neutral	0.265
NPHS1	O60500-1.1	E422R	Neutral	0.251
NPHS1	O60500-1.1	E422S	Neutral	0.307
NPHS1	O60500-1.1	E422T	Neutral	0.222
NPHS1	O60500-1.1	E422V	Neutral	0.376
NPHS1	O60500-1.1	E422W	Pathogenic	0.86
NPHS1	O60500-1.1	E422Y	Neutral	0.444
NPHS1	O60500-1.1	A423C	Pathogenic	0.872
NPHS1	O60500-1.1	A423D	Pathogenic	0.863
NPHS1	O60500-1.1	A423E	Pathogenic	0.922
NPHS1	O60500-1.1	A423F	Pathogenic	0.97
NPHS1	O60500-1.1	A423G	Pathogenic	0.798
NPHS1	O60500-1.1	A423H	Pathogenic	0.757
NPHS1	O60500-1.1	A423I	Pathogenic	0.974
NPHS1	O60500-1.1	A423K	Pathogenic	0.974
NPHS1	O60500-1.1	A423L	Pathogenic	0.97
NPHS1	O60500-1.1	A423M	Pathogenic	0.942
NPHS1	O60500-1.1	A423N	Pathogenic	0.846
NPHS1	O60500-1.1	A423P	Pathogenic	0.772
NPHS1	O60500-1.1	A423Q	Pathogenic	0.877
NPHS1	O60500-1.1	A423R	Pathogenic	0.981
NPHS1	O60500-1.1	A423S	Pathogenic	0.821
NPHS1	O60500-1.1	A423T	Pathogenic	0.761
NPHS1	O60500-1.1	A423V	Pathogenic	0.938
NPHS1	O60500-1.1	A423W	Pathogenic	0.988
NPHS1	O60500-1.1	A423Y	Pathogenic	0.916
NPHS1	O60500-1.1	F424A	Pathogenic	0.994
NPHS1	O60500-1.1	F424C	Pathogenic	0.974
NPHS1	O60500-1.1	F424D	Pathogenic	0.997
NPHS1	O60500-1.1	F424E	Pathogenic	0.994
NPHS1	O60500-1.1	F424G	Pathogenic	0.996
NPHS1	O60500-1.1	F424H	Pathogenic	0.989
NPHS1	O60500-1.1	F424I	Pathogenic	0.911
NPHS1	O60500-1.1	F424K	Pathogenic	0.993
NPHS1	O60500-1.1	F424L	Pathogenic	0.92
NPHS1	O60500-1.1	F424M	Pathogenic	0.958
NPHS1	O60500-1.1	F424N	Pathogenic	0.995
NPHS1	O60500-1.1	F424P	Pathogenic	0.957
NPHS1	O60500-1.1	F424Q	Pathogenic	0.987
NPHS1	O60500-1.1	F424R	Pathogenic	0.995
NPHS1	O60500-1.1	F424S	Pathogenic	0.996
NPHS1	O60500-1.1	F424T	Pathogenic	0.989
NPHS1	O60500-1.1	F424V	Pathogenic	0.961
NPHS1	O60500-1.1	F424W	Pathogenic	0.978
NPHS1	O60500-1.1	F424Y	Pathogenic	0.99
NPHS1	O60500-1.1	T425A	Neutral	0.03
NPHS1	O60500-1.1	T425C	Neutral	0.034
NPHS1	O60500-1.1	T425D	Neutral	0.047
NPHS1	O60500-1.1	T425E	Neutral	0.053
NPHS1	O60500-1.1	T425F	Neutral	0.153
NPHS1	O60500-1.1	T425G	Neutral	0.028
NPHS1	O60500-1.1	T425H	Neutral	0.015
NPHS1	O60500-1.1	T425I	Neutral	0.175
NPHS1	O60500-1.1	T425K	Neutral	0.15
NPHS1	O60500-1.1	T425L	Neutral	0.154
NPHS1	O60500-1.1	T425M	Neutral	0.083
NPHS1	O60500-1.1	T425N	Neutral	0.055
NPHS1	O60500-1.1	T425P	Neutral	0.021
NPHS1	O60500-1.1	T425Q	Neutral	0.033
NPHS1	O60500-1.1	T425R	Neutral	0.197
NPHS1	O60500-1.1	T425S	Neutral	0.053
NPHS1	O60500-1.1	T425V	Neutral	0.078
NPHS1	O60500-1.1	T425W	Neutral	0.411
NPHS1	O60500-1.1	T425Y	Neutral	0.057
NPHS1	O60500-1.1	K426A	Pathogenic	0.947
NPHS1	O60500-1.1	K426C	Pathogenic	0.934
NPHS1	O60500-1.1	K426D	Pathogenic	0.673
NPHS1	O60500-1.1	K426E	Pathogenic	0.784
NPHS1	O60500-1.1	K426F	Pathogenic	0.936
NPHS1	O60500-1.1	K426G	Pathogenic	0.923
NPHS1	O60500-1.1	K426H	Pathogenic	0.806
NPHS1	O60500-1.1	K426I	Pathogenic	0.951
NPHS1	O60500-1.1	K426L	Pathogenic	0.962
NPHS1	O60500-1.1	K426M	Pathogenic	0.949
NPHS1	O60500-1.1	K426N	Pathogenic	0.778
NPHS1	O60500-1.1	K426P	Pathogenic	0.951
NPHS1	O60500-1.1	K426Q	Pathogenic	0.858
NPHS1	O60500-1.1	K426R	Pathogenic	0.707
NPHS1	O60500-1.1	K426S	Pathogenic	0.933
NPHS1	O60500-1.1	K426T	Pathogenic	0.9
NPHS1	O60500-1.1	K426V	Pathogenic	0.95
NPHS1	O60500-1.1	K426W	Pathogenic	0.983
NPHS1	O60500-1.1	K426Y	Pathogenic	0.881
NPHS1	O60500-1.1	E427A	Neutral	0.296
NPHS1	O60500-1.1	E427C	Neutral	0.181
NPHS1	O60500-1.1	E427D	Neutral	0.191
NPHS1	O60500-1.1	E427F	Pathogenic	0.54
NPHS1	O60500-1.1	E427G	Neutral	0.218
NPHS1	O60500-1.1	E427H	Neutral	0.181
NPHS1	O60500-1.1	E427I	Neutral	0.48
NPHS1	O60500-1.1	E427K	Neutral	0.209
NPHS1	O60500-1.1	E427L	Neutral	0.442
NPHS1	O60500-1.1	E427M	Neutral	0.371
NPHS1	O60500-1.1	E427N	Neutral	0.075
NPHS1	O60500-1.1	E427P	Neutral	0.31
NPHS1	O60500-1.1	E427Q	Neutral	0.21
NPHS1	O60500-1.1	E427R	Neutral	0.198
NPHS1	O60500-1.1	E427S	Neutral	0.246
NPHS1	O60500-1.1	E427T	Neutral	0.174
NPHS1	O60500-1.1	E427V	Neutral	0.308
NPHS1	O60500-1.1	E427W	Pathogenic	0.819
NPHS1	O60500-1.1	E427Y	Neutral	0.37
NPHS1	O60500-1.1	T428A	Pathogenic	0.669
NPHS1	O60500-1.1	T428C	Pathogenic	0.703
NPHS1	O60500-1.1	T428D	Pathogenic	0.767
NPHS1	O60500-1.1	T428E	Pathogenic	0.79
NPHS1	O60500-1.1	T428F	Pathogenic	0.923
NPHS1	O60500-1.1	T428G	Pathogenic	0.659
NPHS1	O60500-1.1	T428H	Neutral	0.498
NPHS1	O60500-1.1	T428I	Pathogenic	0.934
NPHS1	O60500-1.1	T428K	Pathogenic	0.921
NPHS1	O60500-1.1	T428L	Pathogenic	0.924
NPHS1	O60500-1.1	T428M	Pathogenic	0.858
NPHS1	O60500-1.1	T428N	Pathogenic	0.796
NPHS1	O60500-1.1	T428P	Pathogenic	0.592
NPHS1	O60500-1.1	T428Q	Pathogenic	0.694
NPHS1	O60500-1.1	T428R	Pathogenic	0.942
NPHS1	O60500-1.1	T428S	Pathogenic	0.79
NPHS1	O60500-1.1	T428V	Pathogenic	0.849
NPHS1	O60500-1.1	T428W	Pathogenic	0.979
NPHS1	O60500-1.1	T428Y	Pathogenic	0.802
NPHS1	O60500-1.1	F429A	Pathogenic	0.934
NPHS1	O60500-1.1	F429C	Pathogenic	0.768
NPHS1	O60500-1.1	F429D	Pathogenic	0.964
NPHS1	O60500-1.1	F429E	Pathogenic	0.935
NPHS1	O60500-1.1	F429G	Pathogenic	0.959
NPHS1	O60500-1.1	F429H	Pathogenic	0.892
NPHS1	O60500-1.1	F429I	Neutral	0.48
NPHS1	O60500-1.1	F429K	Pathogenic	0.929
NPHS1	O60500-1.1	F429L	Pathogenic	0.507
NPHS1	O60500-1.1	F429M	Pathogenic	0.674
NPHS1	O60500-1.1	F429N	Pathogenic	0.949
NPHS1	O60500-1.1	F429P	Pathogenic	0.667
NPHS1	O60500-1.1	F429Q	Pathogenic	0.873
NPHS1	O60500-1.1	F429R	Pathogenic	0.948
NPHS1	O60500-1.1	F429S	Pathogenic	0.954
NPHS1	O60500-1.1	F429T	Pathogenic	0.892
NPHS1	O60500-1.1	F429V	Pathogenic	0.69
NPHS1	O60500-1.1	F429W	Pathogenic	0.8
NPHS1	O60500-1.1	F429Y	Pathogenic	0.901
NPHS1	O60500-1.1	K430A	Pathogenic	0.893
NPHS1	O60500-1.1	K430C	Pathogenic	0.867
NPHS1	O60500-1.1	K430D	Neutral	0.487
NPHS1	O60500-1.1	K430E	Pathogenic	0.627
NPHS1	O60500-1.1	K430F	Pathogenic	0.872
NPHS1	O60500-1.1	K430G	Pathogenic	0.847
NPHS1	O60500-1.1	K430H	Pathogenic	0.657
NPHS1	O60500-1.1	K430I	Pathogenic	0.9
NPHS1	O60500-1.1	K430L	Pathogenic	0.92
NPHS1	O60500-1.1	K430M	Pathogenic	0.895
NPHS1	O60500-1.1	K430N	Pathogenic	0.618
NPHS1	O60500-1.1	K430P	Pathogenic	0.899
NPHS1	O60500-1.1	K430Q	Pathogenic	0.735
NPHS1	O60500-1.1	K430R	Pathogenic	0.527
NPHS1	O60500-1.1	K430S	Pathogenic	0.866
NPHS1	O60500-1.1	K430T	Pathogenic	0.807
NPHS1	O60500-1.1	K430V	Pathogenic	0.898
NPHS1	O60500-1.1	K430W	Pathogenic	0.963
NPHS1	O60500-1.1	K430Y	Pathogenic	0.773
NPHS1	O60500-1.1	K431A	Pathogenic	0.898
NPHS1	O60500-1.1	K431C	Pathogenic	0.874
NPHS1	O60500-1.1	K431D	Pathogenic	0.502
NPHS1	O60500-1.1	K431E	Pathogenic	0.641
NPHS1	O60500-1.1	K431F	Pathogenic	0.878
NPHS1	O60500-1.1	K431G	Pathogenic	0.854
NPHS1	O60500-1.1	K431H	Pathogenic	0.671
NPHS1	O60500-1.1	K431I	Pathogenic	0.905
NPHS1	O60500-1.1	K431L	Pathogenic	0.925
NPHS1	O60500-1.1	K431M	Pathogenic	0.901
NPHS1	O60500-1.1	K431N	Pathogenic	0.632
NPHS1	O60500-1.1	K431P	Pathogenic	0.904
NPHS1	O60500-1.1	K431Q	Pathogenic	0.747
NPHS1	O60500-1.1	K431R	Pathogenic	0.542
NPHS1	O60500-1.1	K431S	Pathogenic	0.873
NPHS1	O60500-1.1	K431T	Pathogenic	0.816
NPHS1	O60500-1.1	K431V	Pathogenic	0.903
NPHS1	O60500-1.1	K431W	Pathogenic	0.965
NPHS1	O60500-1.1	K431Y	Pathogenic	0.783
NPHS1	O60500-1.1	S432A	Neutral	0.078
NPHS1	O60500-1.1	S432C	Neutral	0.109
NPHS1	O60500-1.1	S432D	Neutral	0.118
NPHS1	O60500-1.1	S432E	Neutral	0.144
NPHS1	O60500-1.1	S432F	Neutral	0.465
NPHS1	O60500-1.1	S432G	Neutral	0.053
NPHS1	O60500-1.1	S432H	Neutral	0.069
NPHS1	O60500-1.1	S432I	Neutral	0.406
NPHS1	O60500-1.1	S432K	Neutral	0.345
NPHS1	O60500-1.1	S432L	Neutral	0.37
NPHS1	O60500-1.1	S432M	Neutral	0.303
NPHS1	O60500-1.1	S432N	Neutral	0.149
NPHS1	O60500-1.1	S432P	Neutral	0.083
NPHS1	O60500-1.1	S432Q	Neutral	0.093
NPHS1	O60500-1.1	S432R	Neutral	0.329
NPHS1	O60500-1.1	S432T	Neutral	0.098
NPHS1	O60500-1.1	S432V	Neutral	0.154
NPHS1	O60500-1.1	S432W	Pathogenic	0.692
NPHS1	O60500-1.1	S432Y	Neutral	0.226
NPHS1	O60500-1.1	L433A	Pathogenic	0.778
NPHS1	O60500-1.1	L433C	Neutral	0.451
NPHS1	O60500-1.1	L433D	Pathogenic	0.749
NPHS1	O60500-1.1	L433E	Pathogenic	0.705
NPHS1	O60500-1.1	L433F	Neutral	0.202
NPHS1	O60500-1.1	L433G	Pathogenic	0.724
NPHS1	O60500-1.1	L433H	Neutral	0.38
NPHS1	O60500-1.1	L433I	Neutral	0.307
NPHS1	O60500-1.1	L433K	Pathogenic	0.845
NPHS1	O60500-1.1	L433M	Neutral	0.433
NPHS1	O60500-1.1	L433N	Pathogenic	0.754
NPHS1	O60500-1.1	L433P	Neutral	0.332
NPHS1	O60500-1.1	L433Q	Pathogenic	0.629
NPHS1	O60500-1.1	L433R	Pathogenic	0.884
NPHS1	O60500-1.1	L433S	Pathogenic	0.773
NPHS1	O60500-1.1	L433T	Pathogenic	0.672
NPHS1	O60500-1.1	L433V	Neutral	0.451
NPHS1	O60500-1.1	L433W	Neutral	0.305
NPHS1	O60500-1.1	L433Y	Neutral	0.34
NPHS1	O60500-1.1	I434A	Neutral	0.151
NPHS1	O60500-1.1	I434C	Neutral	0.04
NPHS1	O60500-1.1	I434D	Neutral	0.184
NPHS1	O60500-1.1	I434E	Neutral	0.108
NPHS1	O60500-1.1	I434F	Neutral	0.01
NPHS1	O60500-1.1	I434G	Neutral	0.117
NPHS1	O60500-1.1	I434H	Neutral	0.03
NPHS1	O60500-1.1	I434K	Neutral	0.157
NPHS1	O60500-1.1	I434L	Neutral	0.019
NPHS1	O60500-1.1	I434M	Neutral	0.025
NPHS1	O60500-1.1	I434N	Neutral	0.135
NPHS1	O60500-1.1	I434P	Neutral	0.025
NPHS1	O60500-1.1	I434Q	Neutral	0.055
NPHS1	O60500-1.1	I434R	Neutral	0.206
NPHS1	O60500-1.1	I434S	Neutral	0.148
NPHS1	O60500-1.1	I434T	Neutral	0.094
NPHS1	O60500-1.1	I434V	Neutral	0.085
NPHS1	O60500-1.1	I434W	Neutral	0.011
NPHS1	O60500-1.1	I434Y	Neutral	0.026
NPHS1	O60500-1.1	L435A	Pathogenic	0.987
NPHS1	O60500-1.1	L435C	Pathogenic	0.945
NPHS1	O60500-1.1	L435D	Pathogenic	0.984
NPHS1	O60500-1.1	L435E	Pathogenic	0.981
NPHS1	O60500-1.1	L435F	Pathogenic	0.842
NPHS1	O60500-1.1	L435G	Pathogenic	0.982
NPHS1	O60500-1.1	L435H	Pathogenic	0.928
NPHS1	O60500-1.1	L435I	Pathogenic	0.903
NPHS1	O60500-1.1	L435K	Pathogenic	0.991
NPHS1	O60500-1.1	L435M	Pathogenic	0.942
NPHS1	O60500-1.1	L435N	Pathogenic	0.985
NPHS1	O60500-1.1	L435P	Pathogenic	0.913
NPHS1	O60500-1.1	L435Q	Pathogenic	0.973
NPHS1	O60500-1.1	L435R	Pathogenic	0.994
NPHS1	O60500-1.1	L435S	Pathogenic	0.986
NPHS1	O60500-1.1	L435T	Pathogenic	0.977
NPHS1	O60500-1.1	L435V	Pathogenic	0.945
NPHS1	O60500-1.1	L435W	Pathogenic	0.902
NPHS1	O60500-1.1	L435Y	Pathogenic	0.916
NPHS1	O60500-1.1	N436A	Neutral	0.485
NPHS1	O60500-1.1	N436C	Pathogenic	0.524
NPHS1	O60500-1.1	N436D	Neutral	0.371
NPHS1	O60500-1.1	N436E	Neutral	0.282
NPHS1	O60500-1.1	N436F	Pathogenic	0.879
NPHS1	O60500-1.1	N436G	Pathogenic	0.675
NPHS1	O60500-1.1	N436H	Pathogenic	0.671
NPHS1	O60500-1.1	N436I	Pathogenic	0.851
NPHS1	O60500-1.1	N436K	Pathogenic	0.551
NPHS1	O60500-1.1	N436L	Pathogenic	0.831
NPHS1	O60500-1.1	N436M	Pathogenic	0.785
NPHS1	O60500-1.1	N436P	Pathogenic	0.502
NPHS1	O60500-1.1	N436Q	Neutral	0.424
NPHS1	O60500-1.1	N436R	Pathogenic	0.63
NPHS1	O60500-1.1	N436S	Pathogenic	0.619
NPHS1	O60500-1.1	N436T	Pathogenic	0.513
NPHS1	O60500-1.1	N436V	Pathogenic	0.604
NPHS1	O60500-1.1	N436W	Pathogenic	0.949
NPHS1	O60500-1.1	N436Y	Pathogenic	0.784
NPHS1	O60500-1.1	V437A	Pathogenic	0.968
NPHS1	O60500-1.1	V437C	Pathogenic	0.826
NPHS1	O60500-1.1	V437D	Pathogenic	0.963
NPHS1	O60500-1.1	V437E	Pathogenic	0.961
NPHS1	O60500-1.1	V437F	Pathogenic	0.911
NPHS1	O60500-1.1	V437G	Pathogenic	0.958
NPHS1	O60500-1.1	V437H	Pathogenic	0.868
NPHS1	O60500-1.1	V437I	Pathogenic	0.975
NPHS1	O60500-1.1	V437K	Pathogenic	0.987
NPHS1	O60500-1.1	V437L	Pathogenic	0.939
NPHS1	O60500-1.1	V437M	Pathogenic	0.884
NPHS1	O60500-1.1	V437N	Pathogenic	0.947
NPHS1	O60500-1.1	V437P	Pathogenic	0.811
NPHS1	O60500-1.1	V437Q	Pathogenic	0.938
NPHS1	O60500-1.1	V437R	Pathogenic	0.986
NPHS1	O60500-1.1	V437S	Pathogenic	0.952
NPHS1	O60500-1.1	V437T	Pathogenic	0.947
NPHS1	O60500-1.1	V437W	Pathogenic	0.946
NPHS1	O60500-1.1	V437Y	Pathogenic	0.88
NPHS1	O60500-1.1	K438A	Pathogenic	0.857
NPHS1	O60500-1.1	K438C	Pathogenic	0.825
NPHS1	O60500-1.1	K438D	Neutral	0.406
NPHS1	O60500-1.1	K438E	Pathogenic	0.548
NPHS1	O60500-1.1	K438F	Pathogenic	0.831
NPHS1	O60500-1.1	K438G	Pathogenic	0.8
NPHS1	O60500-1.1	K438H	Pathogenic	0.581
NPHS1	O60500-1.1	K438I	Pathogenic	0.867
NPHS1	O60500-1.1	K438L	Pathogenic	0.893
NPHS1	O60500-1.1	K438M	Pathogenic	0.861
NPHS1	O60500-1.1	K438N	Pathogenic	0.538
NPHS1	O60500-1.1	K438P	Pathogenic	0.865
NPHS1	O60500-1.1	K438Q	Pathogenic	0.667
NPHS1	O60500-1.1	K438R	Neutral	0.446
NPHS1	O60500-1.1	K438S	Pathogenic	0.823
NPHS1	O60500-1.1	K438T	Pathogenic	0.751
NPHS1	O60500-1.1	K438V	Pathogenic	0.864
NPHS1	O60500-1.1	K438W	Pathogenic	0.95
NPHS1	O60500-1.1	K438Y	Pathogenic	0.711
NPHS1	O60500-1.1	Y439A	Pathogenic	0.999
NPHS1	O60500-1.1	Y439C	Pathogenic	0.996
NPHS1	O60500-1.1	Y439D	Pathogenic	0.999
NPHS1	O60500-1.1	Y439E	Pathogenic	0.999
NPHS1	O60500-1.1	Y439F	Pathogenic	0.999
NPHS1	O60500-1.1	Y439G	Pathogenic	0.999
NPHS1	O60500-1.1	Y439H	Pathogenic	0.999
NPHS1	O60500-1.1	Y439I	Pathogenic	0.998
NPHS1	O60500-1.1	Y439K	Pathogenic	0.999
NPHS1	O60500-1.1	Y439L	Pathogenic	0.998
NPHS1	O60500-1.1	Y439M	Pathogenic	0.995
NPHS1	O60500-1.1	Y439N	Pathogenic	0.999
NPHS1	O60500-1.1	Y439P	Pathogenic	0.995
NPHS1	O60500-1.1	Y439Q	Pathogenic	0.999
NPHS1	O60500-1.1	Y439R	Pathogenic	0.999
NPHS1	O60500-1.1	Y439S	Pathogenic	0.999
NPHS1	O60500-1.1	Y439T	Pathogenic	0.998
NPHS1	O60500-1.1	Y439V	Pathogenic	0.997
NPHS1	O60500-1.1	Y439W	Pathogenic	1.0
NPHS1	O60500-1.1	P440A	Pathogenic	0.98
NPHS1	O60500-1.1	P440C	Pathogenic	0.918
NPHS1	O60500-1.1	P440D	Pathogenic	0.993
NPHS1	O60500-1.1	P440E	Pathogenic	0.994
NPHS1	O60500-1.1	P440F	Pathogenic	0.985
NPHS1	O60500-1.1	P440G	Pathogenic	0.988
NPHS1	O60500-1.1	P440H	Pathogenic	0.979
NPHS1	O60500-1.1	P440I	Pathogenic	0.987
NPHS1	O60500-1.1	P440K	Pathogenic	0.998
NPHS1	O60500-1.1	P440L	Pathogenic	0.985
NPHS1	O60500-1.1	P440M	Pathogenic	0.98
NPHS1	O60500-1.1	P440N	Pathogenic	0.988
NPHS1	O60500-1.1	P440Q	Pathogenic	0.991
NPHS1	O60500-1.1	P440R	Pathogenic	0.998
NPHS1	O60500-1.1	P440S	Pathogenic	0.986
NPHS1	O60500-1.1	P440T	Pathogenic	0.97
NPHS1	O60500-1.1	P440V	Pathogenic	0.968
NPHS1	O60500-1.1	P440W	Pathogenic	0.996
NPHS1	O60500-1.1	P440Y	Pathogenic	0.97
NPHS1	O60500-1.1	A441C	Pathogenic	0.726
NPHS1	O60500-1.1	A441D	Pathogenic	0.71
NPHS1	O60500-1.1	A441E	Pathogenic	0.821
NPHS1	O60500-1.1	A441F	Pathogenic	0.926
NPHS1	O60500-1.1	A441G	Pathogenic	0.606
NPHS1	O60500-1.1	A441H	Pathogenic	0.547
NPHS1	O60500-1.1	A441I	Pathogenic	0.937
NPHS1	O60500-1.1	A441K	Pathogenic	0.935
NPHS1	O60500-1.1	A441L	Pathogenic	0.927
NPHS1	O60500-1.1	A441M	Pathogenic	0.863
NPHS1	O60500-1.1	A441N	Pathogenic	0.682
NPHS1	O60500-1.1	A441P	Pathogenic	0.569
NPHS1	O60500-1.1	A441Q	Pathogenic	0.735
NPHS1	O60500-1.1	A441R	Pathogenic	0.952
NPHS1	O60500-1.1	A441S	Pathogenic	0.64
NPHS1	O60500-1.1	A441T	Pathogenic	0.553
NPHS1	O60500-1.1	A441V	Pathogenic	0.855
NPHS1	O60500-1.1	A441W	Pathogenic	0.97
NPHS1	O60500-1.1	A441Y	Pathogenic	0.809
NPHS1	O60500-1.1	Q442A	Pathogenic	0.99
NPHS1	O60500-1.1	Q442C	Pathogenic	0.987
NPHS1	O60500-1.1	Q442D	Pathogenic	0.989
NPHS1	O60500-1.1	Q442E	Pathogenic	0.99
NPHS1	O60500-1.1	Q442F	Pathogenic	0.995
NPHS1	O60500-1.1	Q442G	Pathogenic	0.985
NPHS1	O60500-1.1	Q442H	Pathogenic	0.976
NPHS1	O60500-1.1	Q442I	Pathogenic	0.994
NPHS1	O60500-1.1	Q442K	Pathogenic	0.994
NPHS1	O60500-1.1	Q442L	Pathogenic	0.995
NPHS1	O60500-1.1	Q442M	Pathogenic	0.996
NPHS1	O60500-1.1	Q442N	Pathogenic	0.984
NPHS1	O60500-1.1	Q442P	Pathogenic	0.991
NPHS1	O60500-1.1	Q442R	Pathogenic	0.996
NPHS1	O60500-1.1	Q442S	Pathogenic	0.987
NPHS1	O60500-1.1	Q442T	Pathogenic	0.98
NPHS1	O60500-1.1	Q442V	Pathogenic	0.991
NPHS1	O60500-1.1	Q442W	Pathogenic	0.999
NPHS1	O60500-1.1	Q442Y	Pathogenic	0.994
NPHS1	O60500-1.1	K443A	Pathogenic	0.998
NPHS1	O60500-1.1	K443C	Pathogenic	0.997
NPHS1	O60500-1.1	K443D	Pathogenic	0.979
NPHS1	O60500-1.1	K443E	Pathogenic	0.988
NPHS1	O60500-1.1	K443F	Pathogenic	0.997
NPHS1	O60500-1.1	K443G	Pathogenic	0.996
NPHS1	O60500-1.1	K443H	Pathogenic	0.99
NPHS1	O60500-1.1	K443I	Pathogenic	0.998
NPHS1	O60500-1.1	K443L	Pathogenic	0.998
NPHS1	O60500-1.1	K443M	Pathogenic	0.998
NPHS1	O60500-1.1	K443N	Pathogenic	0.988
NPHS1	O60500-1.1	K443P	Pathogenic	0.998
NPHS1	O60500-1.1	K443Q	Pathogenic	0.993
NPHS1	O60500-1.1	K443R	Pathogenic	0.982
NPHS1	O60500-1.1	K443S	Pathogenic	0.997
NPHS1	O60500-1.1	K443T	Pathogenic	0.995
NPHS1	O60500-1.1	K443V	Pathogenic	0.998
NPHS1	O60500-1.1	K443W	Pathogenic	0.999
NPHS1	O60500-1.1	K443Y	Pathogenic	0.994
NPHS1	O60500-1.1	L444A	Pathogenic	0.867
NPHS1	O60500-1.1	L444C	Pathogenic	0.604
NPHS1	O60500-1.1	L444D	Pathogenic	0.847
NPHS1	O60500-1.1	L444E	Pathogenic	0.816
NPHS1	O60500-1.1	L444F	Neutral	0.319
NPHS1	O60500-1.1	L444G	Pathogenic	0.829
NPHS1	O60500-1.1	L444H	Pathogenic	0.533
NPHS1	O60500-1.1	L444I	Neutral	0.451
NPHS1	O60500-1.1	L444K	Pathogenic	0.91
NPHS1	O60500-1.1	L444M	Pathogenic	0.587
NPHS1	O60500-1.1	L444N	Pathogenic	0.851
NPHS1	O60500-1.1	L444P	Neutral	0.48
NPHS1	O60500-1.1	L444Q	Pathogenic	0.759
NPHS1	O60500-1.1	L444R	Pathogenic	0.934
NPHS1	O60500-1.1	L444S	Pathogenic	0.863
NPHS1	O60500-1.1	L444T	Pathogenic	0.792
NPHS1	O60500-1.1	L444V	Pathogenic	0.604
NPHS1	O60500-1.1	L444W	Neutral	0.449
NPHS1	O60500-1.1	L444Y	Neutral	0.489
NPHS1	O60500-1.1	W445A	Pathogenic	1.0
NPHS1	O60500-1.1	W445C	Pathogenic	1.0
NPHS1	O60500-1.1	W445D	Pathogenic	1.0
NPHS1	O60500-1.1	W445E	Pathogenic	1.0
NPHS1	O60500-1.1	W445F	Pathogenic	0.999
NPHS1	O60500-1.1	W445G	Pathogenic	1.0
NPHS1	O60500-1.1	W445H	Pathogenic	1.0
NPHS1	O60500-1.1	W445I	Pathogenic	0.997
NPHS1	O60500-1.1	W445K	Pathogenic	1.0
NPHS1	O60500-1.1	W445L	Pathogenic	0.998
NPHS1	O60500-1.1	W445M	Pathogenic	0.999
NPHS1	O60500-1.1	W445N	Pathogenic	1.0
NPHS1	O60500-1.1	W445P	Pathogenic	1.0
NPHS1	O60500-1.1	W445Q	Pathogenic	1.0
NPHS1	O60500-1.1	W445R	Pathogenic	1.0
NPHS1	O60500-1.1	W445S	Pathogenic	1.0
NPHS1	O60500-1.1	W445T	Pathogenic	1.0
NPHS1	O60500-1.1	W445V	Pathogenic	0.999
NPHS1	O60500-1.1	W445Y	Pathogenic	1.0
NPHS1	O60500-1.1	I446A	Pathogenic	0.999
NPHS1	O60500-1.1	I446C	Pathogenic	0.994
NPHS1	O60500-1.1	I446D	Pathogenic	0.999
NPHS1	O60500-1.1	I446E	Pathogenic	0.998
NPHS1	O60500-1.1	I446F	Pathogenic	0.975
NPHS1	O60500-1.1	I446G	Pathogenic	0.998
NPHS1	O60500-1.1	I446H	Pathogenic	0.992
NPHS1	O60500-1.1	I446K	Pathogenic	0.999
NPHS1	O60500-1.1	I446L	Pathogenic	0.987
NPHS1	O60500-1.1	I446M	Pathogenic	0.99
NPHS1	O60500-1.1	I446N	Pathogenic	0.998
NPHS1	O60500-1.1	I446P	Pathogenic	0.99
NPHS1	O60500-1.1	I446Q	Pathogenic	0.996
NPHS1	O60500-1.1	I446R	Pathogenic	0.999
NPHS1	O60500-1.1	I446S	Pathogenic	0.999
NPHS1	O60500-1.1	I446T	Pathogenic	0.998
NPHS1	O60500-1.1	I446V	Pathogenic	0.997
NPHS1	O60500-1.1	I446W	Pathogenic	0.978
NPHS1	O60500-1.1	I446Y	Pathogenic	0.99
NPHS1	O60500-1.1	E447A	Pathogenic	0.967
NPHS1	O60500-1.1	E447C	Pathogenic	0.939
NPHS1	O60500-1.1	E447D	Pathogenic	0.943
NPHS1	O60500-1.1	E447F	Pathogenic	0.988
NPHS1	O60500-1.1	E447G	Pathogenic	0.951
NPHS1	O60500-1.1	E447H	Pathogenic	0.939
NPHS1	O60500-1.1	E447I	Pathogenic	0.985
NPHS1	O60500-1.1	E447K	Pathogenic	0.949
NPHS1	O60500-1.1	E447L	Pathogenic	0.982
NPHS1	O60500-1.1	E447M	Pathogenic	0.976
NPHS1	O60500-1.1	E447N	Pathogenic	0.851
NPHS1	O60500-1.1	E447P	Pathogenic	0.969
NPHS1	O60500-1.1	E447Q	Pathogenic	0.949
NPHS1	O60500-1.1	E447R	Pathogenic	0.945
NPHS1	O60500-1.1	E447S	Pathogenic	0.958
NPHS1	O60500-1.1	E447T	Pathogenic	0.937
NPHS1	O60500-1.1	E447V	Pathogenic	0.969
NPHS1	O60500-1.1	E447W	Pathogenic	0.997
NPHS1	O60500-1.1	E447Y	Pathogenic	0.976
NPHS1	O60500-1.1	G448A	Neutral	0.239
NPHS1	O60500-1.1	G448C	Neutral	0.288
NPHS1	O60500-1.1	G448D	Neutral	0.424
NPHS1	O60500-1.1	G448E	Neutral	0.383
NPHS1	O60500-1.1	G448F	Pathogenic	0.81
NPHS1	O60500-1.1	G448H	Neutral	0.266
NPHS1	O60500-1.1	G448I	Pathogenic	0.693
NPHS1	O60500-1.1	G448K	Pathogenic	0.66
NPHS1	O60500-1.1	G448L	Pathogenic	0.66
NPHS1	O60500-1.1	G448M	Pathogenic	0.59
NPHS1	O60500-1.1	G448N	Neutral	0.491
NPHS1	O60500-1.1	G448P	Neutral	0.309
NPHS1	O60500-1.1	G448Q	Neutral	0.273
NPHS1	O60500-1.1	G448R	Pathogenic	0.729
NPHS1	O60500-1.1	G448S	Neutral	0.194
NPHS1	O60500-1.1	G448T	Neutral	0.195
NPHS1	O60500-1.1	G448V	Neutral	0.473
NPHS1	O60500-1.1	G448W	Pathogenic	0.961
NPHS1	O60500-1.1	G448Y	Pathogenic	0.589
NPHS1	O60500-1.1	P449A	Pathogenic	0.875
NPHS1	O60500-1.1	P449C	Pathogenic	0.617
NPHS1	O60500-1.1	P449D	Pathogenic	0.954
NPHS1	O60500-1.1	P449E	Pathogenic	0.963
NPHS1	O60500-1.1	P449F	Pathogenic	0.904
NPHS1	O60500-1.1	P449G	Pathogenic	0.921
NPHS1	O60500-1.1	P449H	Pathogenic	0.873
NPHS1	O60500-1.1	P449I	Pathogenic	0.918
NPHS1	O60500-1.1	P449K	Pathogenic	0.988
NPHS1	O60500-1.1	P449L	Pathogenic	0.905
NPHS1	O60500-1.1	P449M	Pathogenic	0.876
NPHS1	O60500-1.1	P449N	Pathogenic	0.924
NPHS1	O60500-1.1	P449Q	Pathogenic	0.94
NPHS1	O60500-1.1	P449R	Pathogenic	0.987
NPHS1	O60500-1.1	P449S	Pathogenic	0.91
NPHS1	O60500-1.1	P449T	Pathogenic	0.825
NPHS1	O60500-1.1	P449V	Pathogenic	0.816
NPHS1	O60500-1.1	P449W	Pathogenic	0.973
NPHS1	O60500-1.1	P449Y	Pathogenic	0.826
NPHS1	O60500-1.1	P450A	Pathogenic	0.763
NPHS1	O60500-1.1	P450C	Neutral	0.427
NPHS1	O60500-1.1	P450D	Pathogenic	0.905
NPHS1	O60500-1.1	P450E	Pathogenic	0.923
NPHS1	O60500-1.1	P450F	Pathogenic	0.814
NPHS1	O60500-1.1	P450G	Pathogenic	0.843
NPHS1	O60500-1.1	P450H	Pathogenic	0.76
NPHS1	O60500-1.1	P450I	Pathogenic	0.837
NPHS1	O60500-1.1	P450K	Pathogenic	0.974
NPHS1	O60500-1.1	P450L	Pathogenic	0.815
NPHS1	O60500-1.1	P450M	Pathogenic	0.766
NPHS1	O60500-1.1	P450N	Pathogenic	0.849
NPHS1	O60500-1.1	P450Q	Pathogenic	0.879
NPHS1	O60500-1.1	P450R	Pathogenic	0.972
NPHS1	O60500-1.1	P450S	Pathogenic	0.824
NPHS1	O60500-1.1	P450T	Pathogenic	0.685
NPHS1	O60500-1.1	P450V	Pathogenic	0.671
NPHS1	O60500-1.1	P450W	Pathogenic	0.944
NPHS1	O60500-1.1	P450Y	Pathogenic	0.686
NPHS1	O60500-1.1	E451A	Neutral	0.314
NPHS1	O60500-1.1	E451C	Neutral	0.194
NPHS1	O60500-1.1	E451D	Neutral	0.204
NPHS1	O60500-1.1	E451F	Pathogenic	0.561
NPHS1	O60500-1.1	E451G	Neutral	0.234
NPHS1	O60500-1.1	E451H	Neutral	0.194
NPHS1	O60500-1.1	E451I	Pathogenic	0.502
NPHS1	O60500-1.1	E451K	Neutral	0.224
NPHS1	O60500-1.1	E451L	Neutral	0.464
NPHS1	O60500-1.1	E451M	Neutral	0.391
NPHS1	O60500-1.1	E451N	Neutral	0.082
NPHS1	O60500-1.1	E451P	Neutral	0.329
NPHS1	O60500-1.1	E451Q	Neutral	0.224
NPHS1	O60500-1.1	E451R	Neutral	0.212
NPHS1	O60500-1.1	E451S	Neutral	0.262
NPHS1	O60500-1.1	E451T	Neutral	0.187
NPHS1	O60500-1.1	E451V	Neutral	0.326
NPHS1	O60500-1.1	E451W	Pathogenic	0.831
NPHS1	O60500-1.1	E451Y	Neutral	0.391
NPHS1	O60500-1.1	G452A	Neutral	0.243
NPHS1	O60500-1.1	G452C	Neutral	0.293
NPHS1	O60500-1.1	G452D	Neutral	0.43
NPHS1	O60500-1.1	G452E	Neutral	0.389
NPHS1	O60500-1.1	G452F	Pathogenic	0.814
NPHS1	O60500-1.1	G452H	Neutral	0.27
NPHS1	O60500-1.1	G452I	Pathogenic	0.698
NPHS1	O60500-1.1	G452K	Pathogenic	0.665
NPHS1	O60500-1.1	G452L	Pathogenic	0.665
NPHS1	O60500-1.1	G452M	Pathogenic	0.595
NPHS1	O60500-1.1	G452N	Neutral	0.496
NPHS1	O60500-1.1	G452P	Neutral	0.314
NPHS1	O60500-1.1	G452Q	Neutral	0.278
NPHS1	O60500-1.1	G452R	Pathogenic	0.734
NPHS1	O60500-1.1	G452S	Neutral	0.198
NPHS1	O60500-1.1	G452T	Neutral	0.198
NPHS1	O60500-1.1	G452V	Neutral	0.479
NPHS1	O60500-1.1	G452W	Pathogenic	0.962
NPHS1	O60500-1.1	G452Y	Pathogenic	0.595
NPHS1	O60500-1.1	Q453A	Neutral	0.355
NPHS1	O60500-1.1	Q453C	Neutral	0.301
NPHS1	O60500-1.1	Q453D	Neutral	0.325
NPHS1	O60500-1.1	Q453E	Neutral	0.365
NPHS1	O60500-1.1	Q453F	Pathogenic	0.548
NPHS1	O60500-1.1	Q453G	Neutral	0.268
NPHS1	O60500-1.1	Q453H	Neutral	0.186
NPHS1	O60500-1.1	Q453I	Neutral	0.489
NPHS1	O60500-1.1	Q453K	Neutral	0.487
NPHS1	O60500-1.1	Q453L	Pathogenic	0.55
NPHS1	O60500-1.1	Q453M	Pathogenic	0.575
NPHS1	O60500-1.1	Q453N	Neutral	0.25
NPHS1	O60500-1.1	Q453P	Neutral	0.371
NPHS1	O60500-1.1	Q453R	Pathogenic	0.569
NPHS1	O60500-1.1	Q453S	Neutral	0.299
NPHS1	O60500-1.1	Q453T	Neutral	0.216
NPHS1	O60500-1.1	Q453V	Neutral	0.368
NPHS1	O60500-1.1	Q453W	Pathogenic	0.875
NPHS1	O60500-1.1	Q453Y	Neutral	0.475
NPHS1	O60500-1.1	K454A	Neutral	0.01
NPHS1	O60500-1.1	K454C	Neutral	0.008
NPHS1	O60500-1.1	K454D	Neutral	0.001
NPHS1	O60500-1.1	K454E	Neutral	0.002
NPHS1	O60500-1.1	K454F	Neutral	0.009
NPHS1	O60500-1.1	K454G	Neutral	0.007
NPHS1	O60500-1.1	K454H	Neutral	0.002
NPHS1	O60500-1.1	K454I	Neutral	0.011
NPHS1	O60500-1.1	K454L	Neutral	0.014
NPHS1	O60500-1.1	K454M	Neutral	0.011
NPHS1	O60500-1.1	K454N	Neutral	0.002
NPHS1	O60500-1.1	K454P	Neutral	0.011
NPHS1	O60500-1.1	K454Q	Neutral	0.003
NPHS1	O60500-1.1	K454R	Neutral	0.001
NPHS1	O60500-1.1	K454S	Neutral	0.008
NPHS1	O60500-1.1	K454T	Neutral	0.005
NPHS1	O60500-1.1	K454V	Neutral	0.011
NPHS1	O60500-1.1	K454W	Neutral	0.032
NPHS1	O60500-1.1	K454Y	Neutral	0.004
NPHS1	O60500-1.1	L455A	Pathogenic	0.704
NPHS1	O60500-1.1	L455C	Neutral	0.357
NPHS1	O60500-1.1	L455D	Pathogenic	0.669
NPHS1	O60500-1.1	L455E	Pathogenic	0.618
NPHS1	O60500-1.1	L455F	Neutral	0.146
NPHS1	O60500-1.1	L455G	Pathogenic	0.639
NPHS1	O60500-1.1	L455H	Neutral	0.294
NPHS1	O60500-1.1	L455I	Neutral	0.231
NPHS1	O60500-1.1	L455K	Pathogenic	0.787
NPHS1	O60500-1.1	L455M	Neutral	0.341
NPHS1	O60500-1.1	L455N	Pathogenic	0.676
NPHS1	O60500-1.1	L455P	Neutral	0.252
NPHS1	O60500-1.1	L455Q	Pathogenic	0.535
NPHS1	O60500-1.1	L455R	Pathogenic	0.837
NPHS1	O60500-1.1	L455S	Pathogenic	0.698
NPHS1	O60500-1.1	L455T	Pathogenic	0.581
NPHS1	O60500-1.1	L455V	Neutral	0.357
NPHS1	O60500-1.1	L455W	Neutral	0.229
NPHS1	O60500-1.1	L455Y	Neutral	0.259
NPHS1	O60500-1.1	R456A	Pathogenic	0.999
NPHS1	O60500-1.1	R456C	Pathogenic	0.999
NPHS1	O60500-1.1	R456D	Pathogenic	0.99
NPHS1	O60500-1.1	R456E	Pathogenic	0.994
NPHS1	O60500-1.1	R456F	Pathogenic	0.999
NPHS1	O60500-1.1	R456G	Pathogenic	0.999
NPHS1	O60500-1.1	R456H	Pathogenic	0.998
NPHS1	O60500-1.1	R456I	Pathogenic	0.999
NPHS1	O60500-1.1	R456K	Pathogenic	0.992
NPHS1	O60500-1.1	R456L	Pathogenic	0.999
NPHS1	O60500-1.1	R456M	Pathogenic	0.999
NPHS1	O60500-1.1	R456N	Pathogenic	0.996
NPHS1	O60500-1.1	R456P	Pathogenic	0.999
NPHS1	O60500-1.1	R456Q	Pathogenic	0.998
NPHS1	O60500-1.1	R456S	Pathogenic	0.998
NPHS1	O60500-1.1	R456T	Pathogenic	0.998
NPHS1	O60500-1.1	R456V	Pathogenic	0.999
NPHS1	O60500-1.1	R456W	Pathogenic	1.0
NPHS1	O60500-1.1	R456Y	Pathogenic	0.997
NPHS1	O60500-1.1	A457C	Pathogenic	0.558
NPHS1	O60500-1.1	A457D	Pathogenic	0.538
NPHS1	O60500-1.1	A457E	Pathogenic	0.686
NPHS1	O60500-1.1	A457F	Pathogenic	0.857
NPHS1	O60500-1.1	A457G	Neutral	0.423
NPHS1	O60500-1.1	A457H	Neutral	0.365
NPHS1	O60500-1.1	A457I	Pathogenic	0.876
NPHS1	O60500-1.1	A457K	Pathogenic	0.872
NPHS1	O60500-1.1	A457L	Pathogenic	0.858
NPHS1	O60500-1.1	A457M	Pathogenic	0.751
NPHS1	O60500-1.1	A457N	Pathogenic	0.505
NPHS1	O60500-1.1	A457P	Neutral	0.386
NPHS1	O60500-1.1	A457Q	Pathogenic	0.569
NPHS1	O60500-1.1	A457R	Pathogenic	0.904
NPHS1	O60500-1.1	A457S	Neutral	0.459
NPHS1	O60500-1.1	A457T	Neutral	0.371
NPHS1	O60500-1.1	A457V	Pathogenic	0.737
NPHS1	O60500-1.1	A457W	Pathogenic	0.939
NPHS1	O60500-1.1	A457Y	Pathogenic	0.668
NPHS1	O60500-1.1	G458A	Pathogenic	0.986
NPHS1	O60500-1.1	G458C	Pathogenic	0.989
NPHS1	O60500-1.1	G458D	Pathogenic	0.994
NPHS1	O60500-1.1	G458E	Pathogenic	0.993
NPHS1	O60500-1.1	G458F	Pathogenic	0.999
NPHS1	O60500-1.1	G458H	Pathogenic	0.987
NPHS1	O60500-1.1	G458I	Pathogenic	0.998
NPHS1	O60500-1.1	G458K	Pathogenic	0.998
NPHS1	O60500-1.1	G458L	Pathogenic	0.998
NPHS1	O60500-1.1	G458M	Pathogenic	0.997
NPHS1	O60500-1.1	G458N	Pathogenic	0.995
NPHS1	O60500-1.1	G458P	Pathogenic	0.99
NPHS1	O60500-1.1	G458Q	Pathogenic	0.988
NPHS1	O60500-1.1	G458R	Pathogenic	0.998
NPHS1	O60500-1.1	G458S	Pathogenic	0.981
NPHS1	O60500-1.1	G458T	Pathogenic	0.981
NPHS1	O60500-1.1	G458V	Pathogenic	0.995
NPHS1	O60500-1.1	G458W	Pathogenic	1.0
NPHS1	O60500-1.1	G458Y	Pathogenic	0.997
NPHS1	O60500-1.1	T459A	Pathogenic	0.775
NPHS1	O60500-1.1	T459C	Pathogenic	0.801
NPHS1	O60500-1.1	T459D	Pathogenic	0.848
NPHS1	O60500-1.1	T459E	Pathogenic	0.865
NPHS1	O60500-1.1	T459F	Pathogenic	0.953
NPHS1	O60500-1.1	T459G	Pathogenic	0.767
NPHS1	O60500-1.1	T459H	Pathogenic	0.627
NPHS1	O60500-1.1	T459I	Pathogenic	0.96
NPHS1	O60500-1.1	T459K	Pathogenic	0.952
NPHS1	O60500-1.1	T459L	Pathogenic	0.954
NPHS1	O60500-1.1	T459M	Pathogenic	0.911
NPHS1	O60500-1.1	T459N	Pathogenic	0.869
NPHS1	O60500-1.1	T459P	Pathogenic	0.712
NPHS1	O60500-1.1	T459Q	Pathogenic	0.794
NPHS1	O60500-1.1	T459R	Pathogenic	0.965
NPHS1	O60500-1.1	T459S	Pathogenic	0.864
NPHS1	O60500-1.1	T459V	Pathogenic	0.905
NPHS1	O60500-1.1	T459W	Pathogenic	0.987
NPHS1	O60500-1.1	T459Y	Pathogenic	0.873
NPHS1	O60500-1.1	R460A	Pathogenic	0.763
NPHS1	O60500-1.1	R460C	Pathogenic	0.716
NPHS1	O60500-1.1	R460D	Neutral	0.198
NPHS1	O60500-1.1	R460E	Neutral	0.304
NPHS1	O60500-1.1	R460F	Pathogenic	0.725
NPHS1	O60500-1.1	R460G	Pathogenic	0.682
NPHS1	O60500-1.1	R460H	Pathogenic	0.526
NPHS1	O60500-1.1	R460I	Pathogenic	0.777
NPHS1	O60500-1.1	R460K	Neutral	0.237
NPHS1	O60500-1.1	R460L	Pathogenic	0.817
NPHS1	O60500-1.1	R460M	Pathogenic	0.768
NPHS1	O60500-1.1	R460N	Neutral	0.385
NPHS1	O60500-1.1	R460P	Pathogenic	0.698
NPHS1	O60500-1.1	R460Q	Pathogenic	0.518
NPHS1	O60500-1.1	R460S	Pathogenic	0.626
NPHS1	O60500-1.1	R460T	Pathogenic	0.618
NPHS1	O60500-1.1	R460V	Pathogenic	0.695
NPHS1	O60500-1.1	R460W	Pathogenic	0.846
NPHS1	O60500-1.1	R460Y	Neutral	0.498
NPHS1	O60500-1.1	V461A	Pathogenic	0.976
NPHS1	O60500-1.1	V461C	Pathogenic	0.864
NPHS1	O60500-1.1	V461D	Pathogenic	0.972
NPHS1	O60500-1.1	V461E	Pathogenic	0.971
NPHS1	O60500-1.1	V461F	Pathogenic	0.931
NPHS1	O60500-1.1	V461G	Pathogenic	0.968
NPHS1	O60500-1.1	V461H	Pathogenic	0.898
NPHS1	O60500-1.1	V461I	Pathogenic	0.981
NPHS1	O60500-1.1	V461K	Pathogenic	0.99
NPHS1	O60500-1.1	V461L	Pathogenic	0.953
NPHS1	O60500-1.1	V461M	Pathogenic	0.91
NPHS1	O60500-1.1	V461N	Pathogenic	0.96
NPHS1	O60500-1.1	V461P	Pathogenic	0.851
NPHS1	O60500-1.1	V461Q	Pathogenic	0.953
NPHS1	O60500-1.1	V461R	Pathogenic	0.99
NPHS1	O60500-1.1	V461S	Pathogenic	0.963
NPHS1	O60500-1.1	V461T	Pathogenic	0.959
NPHS1	O60500-1.1	V461W	Pathogenic	0.959
NPHS1	O60500-1.1	V461Y	Pathogenic	0.907
NPHS1	O60500-1.1	R462A	Pathogenic	0.956
NPHS1	O60500-1.1	R462C	Pathogenic	0.945
NPHS1	O60500-1.1	R462D	Pathogenic	0.625
NPHS1	O60500-1.1	R462E	Pathogenic	0.747
NPHS1	O60500-1.1	R462F	Pathogenic	0.947
NPHS1	O60500-1.1	R462G	Pathogenic	0.935
NPHS1	O60500-1.1	R462H	Pathogenic	0.882
NPHS1	O60500-1.1	R462I	Pathogenic	0.959
NPHS1	O60500-1.1	R462K	Pathogenic	0.678
NPHS1	O60500-1.1	R462L	Pathogenic	0.968
NPHS1	O60500-1.1	R462M	Pathogenic	0.957
NPHS1	O60500-1.1	R462N	Pathogenic	0.809
NPHS1	O60500-1.1	R462P	Pathogenic	0.94
NPHS1	O60500-1.1	R462Q	Pathogenic	0.879
NPHS1	O60500-1.1	R462S	Pathogenic	0.919
NPHS1	O60500-1.1	R462T	Pathogenic	0.916
NPHS1	O60500-1.1	R462V	Pathogenic	0.939
NPHS1	O60500-1.1	R462W	Pathogenic	0.974
NPHS1	O60500-1.1	R462Y	Pathogenic	0.87
NPHS1	O60500-1.1	L463A	Pathogenic	0.985
NPHS1	O60500-1.1	L463C	Pathogenic	0.939
NPHS1	O60500-1.1	L463D	Pathogenic	0.983
NPHS1	O60500-1.1	L463E	Pathogenic	0.978
NPHS1	O60500-1.1	L463F	Pathogenic	0.827
NPHS1	O60500-1.1	L463G	Pathogenic	0.98
NPHS1	O60500-1.1	L463H	Pathogenic	0.92
NPHS1	O60500-1.1	L463I	Pathogenic	0.893
NPHS1	O60500-1.1	L463K	Pathogenic	0.99
NPHS1	O60500-1.1	L463M	Pathogenic	0.935
NPHS1	O60500-1.1	L463N	Pathogenic	0.983
NPHS1	O60500-1.1	L463P	Pathogenic	0.904
NPHS1	O60500-1.1	L463Q	Pathogenic	0.97
NPHS1	O60500-1.1	L463R	Pathogenic	0.993
NPHS1	O60500-1.1	L463S	Pathogenic	0.985
NPHS1	O60500-1.1	L463T	Pathogenic	0.975
NPHS1	O60500-1.1	L463V	Pathogenic	0.939
NPHS1	O60500-1.1	L463W	Pathogenic	0.892
NPHS1	O60500-1.1	L463Y	Pathogenic	0.907
NPHS1	O60500-1.1	V464A	Neutral	0.483
NPHS1	O60500-1.1	V464C	Neutral	0.128
NPHS1	O60500-1.1	V464D	Neutral	0.443
NPHS1	O60500-1.1	V464E	Neutral	0.435
NPHS1	O60500-1.1	V464F	Neutral	0.239
NPHS1	O60500-1.1	V464G	Neutral	0.411
NPHS1	O60500-1.1	V464H	Neutral	0.169
NPHS1	O60500-1.1	V464I	Pathogenic	0.551
NPHS1	O60500-1.1	V464K	Pathogenic	0.706
NPHS1	O60500-1.1	V464L	Neutral	0.321
NPHS1	O60500-1.1	V464M	Neutral	0.19
NPHS1	O60500-1.1	V464N	Neutral	0.355
NPHS1	O60500-1.1	V464P	Neutral	0.117
NPHS1	O60500-1.1	V464Q	Neutral	0.317
NPHS1	O60500-1.1	V464R	Pathogenic	0.691
NPHS1	O60500-1.1	V464S	Neutral	0.379
NPHS1	O60500-1.1	V464T	Neutral	0.353
NPHS1	O60500-1.1	V464W	Neutral	0.353
NPHS1	O60500-1.1	V464Y	Neutral	0.185
NPHS1	O60500-1.1	C465A	Pathogenic	0.984
NPHS1	O60500-1.1	C465D	Pathogenic	0.985
NPHS1	O60500-1.1	C465E	Pathogenic	0.982
NPHS1	O60500-1.1	C465F	Pathogenic	0.986
NPHS1	O60500-1.1	C465G	Pathogenic	0.979
NPHS1	O60500-1.1	C465H	Pathogenic	0.97
NPHS1	O60500-1.1	C465I	Pathogenic	0.988
NPHS1	O60500-1.1	C465K	Pathogenic	0.996
NPHS1	O60500-1.1	C465L	Pathogenic	0.986
NPHS1	O60500-1.1	C465M	Pathogenic	0.972
NPHS1	O60500-1.1	C465N	Pathogenic	0.983
NPHS1	O60500-1.1	C465P	Pathogenic	0.876
NPHS1	O60500-1.1	C465Q	Pathogenic	0.981
NPHS1	O60500-1.1	C465R	Pathogenic	0.997
NPHS1	O60500-1.1	C465S	Pathogenic	0.984
NPHS1	O60500-1.1	C465T	Pathogenic	0.971
NPHS1	O60500-1.1	C465V	Pathogenic	0.956
NPHS1	O60500-1.1	C465W	Pathogenic	0.996
NPHS1	O60500-1.1	C465Y	Pathogenic	0.961
NPHS1	O60500-1.1	L466A	Pathogenic	0.693
NPHS1	O60500-1.1	L466C	Neutral	0.346
NPHS1	O60500-1.1	L466D	Pathogenic	0.657
NPHS1	O60500-1.1	L466E	Pathogenic	0.606
NPHS1	O60500-1.1	L466F	Neutral	0.14
NPHS1	O60500-1.1	L466G	Pathogenic	0.628
NPHS1	O60500-1.1	L466H	Neutral	0.283
NPHS1	O60500-1.1	L466I	Neutral	0.222
NPHS1	O60500-1.1	L466K	Pathogenic	0.779
NPHS1	O60500-1.1	L466M	Neutral	0.33
NPHS1	O60500-1.1	L466N	Pathogenic	0.664
NPHS1	O60500-1.1	L466P	Neutral	0.242
NPHS1	O60500-1.1	L466Q	Pathogenic	0.522
NPHS1	O60500-1.1	L466R	Pathogenic	0.83
NPHS1	O60500-1.1	L466S	Pathogenic	0.687
NPHS1	O60500-1.1	L466T	Pathogenic	0.569
NPHS1	O60500-1.1	L466V	Neutral	0.346
NPHS1	O60500-1.1	L466W	Neutral	0.22
NPHS1	O60500-1.1	L466Y	Neutral	0.249
NPHS1	O60500-1.1	A467C	Pathogenic	0.782
NPHS1	O60500-1.1	A467D	Pathogenic	0.767
NPHS1	O60500-1.1	A467E	Pathogenic	0.861
NPHS1	O60500-1.1	A467F	Pathogenic	0.944
NPHS1	O60500-1.1	A467G	Pathogenic	0.675
NPHS1	O60500-1.1	A467H	Pathogenic	0.62
NPHS1	O60500-1.1	A467I	Pathogenic	0.952
NPHS1	O60500-1.1	A467K	Pathogenic	0.951
NPHS1	O60500-1.1	A467L	Pathogenic	0.945
NPHS1	O60500-1.1	A467M	Pathogenic	0.895
NPHS1	O60500-1.1	A467N	Pathogenic	0.743
NPHS1	O60500-1.1	A467P	Pathogenic	0.64
NPHS1	O60500-1.1	A467Q	Pathogenic	0.789
NPHS1	O60500-1.1	A467R	Pathogenic	0.964
NPHS1	O60500-1.1	A467S	Pathogenic	0.706
NPHS1	O60500-1.1	A467T	Pathogenic	0.626
NPHS1	O60500-1.1	A467V	Pathogenic	0.888
NPHS1	O60500-1.1	A467W	Pathogenic	0.978
NPHS1	O60500-1.1	A467Y	Pathogenic	0.851
NPHS1	O60500-1.1	I468A	Pathogenic	0.957
NPHS1	O60500-1.1	I468C	Pathogenic	0.839
NPHS1	O60500-1.1	I468D	Pathogenic	0.966
NPHS1	O60500-1.1	I468E	Pathogenic	0.938
NPHS1	O60500-1.1	I468F	Pathogenic	0.554
NPHS1	O60500-1.1	I468G	Pathogenic	0.943
NPHS1	O60500-1.1	I468H	Pathogenic	0.796
NPHS1	O60500-1.1	I468K	Pathogenic	0.959
NPHS1	O60500-1.1	I468L	Pathogenic	0.708
NPHS1	O60500-1.1	I468M	Pathogenic	0.766
NPHS1	O60500-1.1	I468N	Pathogenic	0.951
NPHS1	O60500-1.1	I468P	Pathogenic	0.76
NPHS1	O60500-1.1	I468Q	Pathogenic	0.879
NPHS1	O60500-1.1	I468R	Pathogenic	0.97
NPHS1	O60500-1.1	I468S	Pathogenic	0.956
NPHS1	O60500-1.1	I468T	Pathogenic	0.929
NPHS1	O60500-1.1	I468V	Pathogenic	0.921
NPHS1	O60500-1.1	I468W	Pathogenic	0.58
NPHS1	O60500-1.1	I468Y	Pathogenic	0.767
NPHS1	O60500-1.1	G469A	Pathogenic	0.966
NPHS1	O60500-1.1	G469C	Pathogenic	0.973
NPHS1	O60500-1.1	G469D	Pathogenic	0.985
NPHS1	O60500-1.1	G469E	Pathogenic	0.983
NPHS1	O60500-1.1	G469F	Pathogenic	0.997
NPHS1	O60500-1.1	G469H	Pathogenic	0.97
NPHS1	O60500-1.1	G469I	Pathogenic	0.995
NPHS1	O60500-1.1	G469K	Pathogenic	0.994
NPHS1	O60500-1.1	G469L	Pathogenic	0.994
NPHS1	O60500-1.1	G469M	Pathogenic	0.992
NPHS1	O60500-1.1	G469N	Pathogenic	0.989
NPHS1	O60500-1.1	G469P	Pathogenic	0.976
NPHS1	O60500-1.1	G469Q	Pathogenic	0.971
NPHS1	O60500-1.1	G469R	Pathogenic	0.996
NPHS1	O60500-1.1	G469S	Pathogenic	0.956
NPHS1	O60500-1.1	G469T	Pathogenic	0.956
NPHS1	O60500-1.1	G469V	Pathogenic	0.988
NPHS1	O60500-1.1	G469W	Pathogenic	1.0
NPHS1	O60500-1.1	G469Y	Pathogenic	0.992
NPHS1	O60500-1.1	G470A	Pathogenic	0.984
NPHS1	O60500-1.1	G470C	Pathogenic	0.988
NPHS1	O60500-1.1	G470D	Pathogenic	0.993
NPHS1	O60500-1.1	G470E	Pathogenic	0.992
NPHS1	O60500-1.1	G470F	Pathogenic	0.999
NPHS1	O60500-1.1	G470H	Pathogenic	0.986
NPHS1	O60500-1.1	G470I	Pathogenic	0.998
NPHS1	O60500-1.1	G470K	Pathogenic	0.997
NPHS1	O60500-1.1	G470L	Pathogenic	0.997
NPHS1	O60500-1.1	G470M	Pathogenic	0.996
NPHS1	O60500-1.1	G470N	Pathogenic	0.995
NPHS1	O60500-1.1	G470P	Pathogenic	0.989
NPHS1	O60500-1.1	G470Q	Pathogenic	0.987
NPHS1	O60500-1.1	G470R	Pathogenic	0.998
NPHS1	O60500-1.1	G470S	Pathogenic	0.979
NPHS1	O60500-1.1	G470T	Pathogenic	0.979
NPHS1	O60500-1.1	G470V	Pathogenic	0.994
NPHS1	O60500-1.1	G470W	Pathogenic	1.0
NPHS1	O60500-1.1	G470Y	Pathogenic	0.996
NPHS1	O60500-1.1	N471A	Pathogenic	0.993
NPHS1	O60500-1.1	N471C	Pathogenic	0.994
NPHS1	O60500-1.1	N471D	Pathogenic	0.989
NPHS1	O60500-1.1	N471E	Pathogenic	0.984
NPHS1	O60500-1.1	N471F	Pathogenic	0.999
NPHS1	O60500-1.1	N471G	Pathogenic	0.997
NPHS1	O60500-1.1	N471H	Pathogenic	0.997
NPHS1	O60500-1.1	N471I	Pathogenic	0.999
NPHS1	O60500-1.1	N471K	Pathogenic	0.995
NPHS1	O60500-1.1	N471L	Pathogenic	0.999
NPHS1	O60500-1.1	N471M	Pathogenic	0.998
NPHS1	O60500-1.1	N471P	Pathogenic	0.994
NPHS1	O60500-1.1	N471Q	Pathogenic	0.992
NPHS1	O60500-1.1	N471R	Pathogenic	0.996
NPHS1	O60500-1.1	N471S	Pathogenic	0.996
NPHS1	O60500-1.1	N471T	Pathogenic	0.994
NPHS1	O60500-1.1	N471V	Pathogenic	0.996
NPHS1	O60500-1.1	N471W	Pathogenic	1.0
NPHS1	O60500-1.1	N471Y	Pathogenic	0.998
NPHS1	O60500-1.1	P472A	Pathogenic	0.982
NPHS1	O60500-1.1	P472C	Pathogenic	0.928
NPHS1	O60500-1.1	P472D	Pathogenic	0.994
NPHS1	O60500-1.1	P472E	Pathogenic	0.995
NPHS1	O60500-1.1	P472F	Pathogenic	0.987
NPHS1	O60500-1.1	P472G	Pathogenic	0.989
NPHS1	O60500-1.1	P472H	Pathogenic	0.982
NPHS1	O60500-1.1	P472I	Pathogenic	0.989
NPHS1	O60500-1.1	P472K	Pathogenic	0.998
NPHS1	O60500-1.1	P472L	Pathogenic	0.987
NPHS1	O60500-1.1	P472M	Pathogenic	0.983
NPHS1	O60500-1.1	P472N	Pathogenic	0.99
NPHS1	O60500-1.1	P472Q	Pathogenic	0.992
NPHS1	O60500-1.1	P472R	Pathogenic	0.998
NPHS1	O60500-1.1	P472S	Pathogenic	0.988
NPHS1	O60500-1.1	P472T	Pathogenic	0.974
NPHS1	O60500-1.1	P472V	Pathogenic	0.972
NPHS1	O60500-1.1	P472W	Pathogenic	0.997
NPHS1	O60500-1.1	P472Y	Pathogenic	0.974
NPHS1	O60500-1.1	E473A	Neutral	0.011
NPHS1	O60500-1.1	E473C	Neutral	0.006
NPHS1	O60500-1.1	E473D	Neutral	0.006
NPHS1	O60500-1.1	E473F	Neutral	0.031
NPHS1	O60500-1.1	E473G	Neutral	0.008
NPHS1	O60500-1.1	E473H	Neutral	0.006
NPHS1	O60500-1.1	E473I	Neutral	0.025
NPHS1	O60500-1.1	E473K	Neutral	0.007
NPHS1	O60500-1.1	E473L	Neutral	0.021
NPHS1	O60500-1.1	E473M	Neutral	0.016
NPHS1	O60500-1.1	E473N	Neutral	0.002
NPHS1	O60500-1.1	E473P	Neutral	0.012
NPHS1	O60500-1.1	E473Q	Neutral	0.007
NPHS1	O60500-1.1	E473R	Neutral	0.007
NPHS1	O60500-1.1	E473S	Neutral	0.009
NPHS1	O60500-1.1	E473T	Neutral	0.006
NPHS1	O60500-1.1	E473V	Neutral	0.012
NPHS1	O60500-1.1	E473W	Neutral	0.11
NPHS1	O60500-1.1	E473Y	Neutral	0.016
NPHS1	O60500-1.1	P474A	Pathogenic	0.834
NPHS1	O60500-1.1	P474C	Pathogenic	0.537
NPHS1	O60500-1.1	P474D	Pathogenic	0.937
NPHS1	O60500-1.1	P474E	Pathogenic	0.949
NPHS1	O60500-1.1	P474F	Pathogenic	0.872
NPHS1	O60500-1.1	P474G	Pathogenic	0.893
NPHS1	O60500-1.1	P474H	Pathogenic	0.831
NPHS1	O60500-1.1	P474I	Pathogenic	0.889
NPHS1	O60500-1.1	P474K	Pathogenic	0.983
NPHS1	O60500-1.1	P474L	Pathogenic	0.873
NPHS1	O60500-1.1	P474M	Pathogenic	0.836
NPHS1	O60500-1.1	P474N	Pathogenic	0.897
NPHS1	O60500-1.1	P474Q	Pathogenic	0.919
NPHS1	O60500-1.1	P474R	Pathogenic	0.982
NPHS1	O60500-1.1	P474S	Pathogenic	0.879
NPHS1	O60500-1.1	P474T	Pathogenic	0.772
NPHS1	O60500-1.1	P474V	Pathogenic	0.761
NPHS1	O60500-1.1	P474W	Pathogenic	0.963
NPHS1	O60500-1.1	P474Y	Pathogenic	0.773
NPHS1	O60500-1.1	S475A	Neutral	0.173
NPHS1	O60500-1.1	S475C	Neutral	0.232
NPHS1	O60500-1.1	S475D	Neutral	0.249
NPHS1	O60500-1.1	S475E	Neutral	0.294
NPHS1	O60500-1.1	S475F	Pathogenic	0.682
NPHS1	O60500-1.1	S475G	Neutral	0.122
NPHS1	O60500-1.1	S475H	Neutral	0.154
NPHS1	O60500-1.1	S475I	Pathogenic	0.628
NPHS1	O60500-1.1	S475K	Pathogenic	0.565
NPHS1	O60500-1.1	S475L	Pathogenic	0.592
NPHS1	O60500-1.1	S475M	Pathogenic	0.518
NPHS1	O60500-1.1	S475N	Neutral	0.302
NPHS1	O60500-1.1	S475P	Neutral	0.183
NPHS1	O60500-1.1	S475Q	Neutral	0.201
NPHS1	O60500-1.1	S475R	Pathogenic	0.548
NPHS1	O60500-1.1	S475T	Neutral	0.212
NPHS1	O60500-1.1	S475V	Neutral	0.31
NPHS1	O60500-1.1	S475W	Pathogenic	0.847
NPHS1	O60500-1.1	S475Y	Neutral	0.418
NPHS1	O60500-1.1	L476A	Pathogenic	0.997
NPHS1	O60500-1.1	L476C	Pathogenic	0.986
NPHS1	O60500-1.1	L476D	Pathogenic	0.996
NPHS1	O60500-1.1	L476E	Pathogenic	0.995
NPHS1	O60500-1.1	L476F	Pathogenic	0.955
NPHS1	O60500-1.1	L476G	Pathogenic	0.995
NPHS1	O60500-1.1	L476H	Pathogenic	0.981
NPHS1	O60500-1.1	L476I	Pathogenic	0.974
NPHS1	O60500-1.1	L476K	Pathogenic	0.998
NPHS1	O60500-1.1	L476M	Pathogenic	0.985
NPHS1	O60500-1.1	L476N	Pathogenic	0.996
NPHS1	O60500-1.1	L476P	Pathogenic	0.976
NPHS1	O60500-1.1	L476Q	Pathogenic	0.993
NPHS1	O60500-1.1	L476R	Pathogenic	0.998
NPHS1	O60500-1.1	L476S	Pathogenic	0.996
NPHS1	O60500-1.1	L476T	Pathogenic	0.994
NPHS1	O60500-1.1	L476V	Pathogenic	0.986
NPHS1	O60500-1.1	L476W	Pathogenic	0.973
NPHS1	O60500-1.1	L476Y	Pathogenic	0.977
NPHS1	O60500-1.1	M477A	Neutral	0.382
NPHS1	O60500-1.1	M477C	Neutral	0.126
NPHS1	O60500-1.1	M477D	Neutral	0.439
NPHS1	O60500-1.1	M477E	Neutral	0.385
NPHS1	O60500-1.1	M477F	Neutral	0.152
NPHS1	O60500-1.1	M477G	Neutral	0.407
NPHS1	O60500-1.1	M477H	Neutral	0.139
NPHS1	O60500-1.1	M477I	Neutral	0.174
NPHS1	O60500-1.1	M477K	Pathogenic	0.589
NPHS1	O60500-1.1	M477L	Neutral	0.213
NPHS1	O60500-1.1	M477N	Neutral	0.446
NPHS1	O60500-1.1	M477P	Neutral	0.115
NPHS1	O60500-1.1	M477Q	Neutral	0.399
NPHS1	O60500-1.1	M477R	Pathogenic	0.666
NPHS1	O60500-1.1	M477S	Neutral	0.472
NPHS1	O60500-1.1	M477T	Neutral	0.265
NPHS1	O60500-1.1	M477V	Neutral	0.126
NPHS1	O60500-1.1	M477W	Neutral	0.317
NPHS1	O60500-1.1	M477Y	Neutral	0.083
NPHS1	O60500-1.1	W478A	Pathogenic	1.0
NPHS1	O60500-1.1	W478C	Pathogenic	1.0
NPHS1	O60500-1.1	W478D	Pathogenic	1.0
NPHS1	O60500-1.1	W478E	Pathogenic	1.0
NPHS1	O60500-1.1	W478F	Pathogenic	1.0
NPHS1	O60500-1.1	W478G	Pathogenic	1.0
NPHS1	O60500-1.1	W478H	Pathogenic	1.0
NPHS1	O60500-1.1	W478I	Pathogenic	0.998
NPHS1	O60500-1.1	W478K	Pathogenic	1.0
NPHS1	O60500-1.1	W478L	Pathogenic	0.999
NPHS1	O60500-1.1	W478M	Pathogenic	1.0
NPHS1	O60500-1.1	W478N	Pathogenic	1.0
NPHS1	O60500-1.1	W478P	Pathogenic	1.0
NPHS1	O60500-1.1	W478Q	Pathogenic	1.0
NPHS1	O60500-1.1	W478R	Pathogenic	1.0
NPHS1	O60500-1.1	W478S	Pathogenic	1.0
NPHS1	O60500-1.1	W478T	Pathogenic	1.0
NPHS1	O60500-1.1	W478V	Pathogenic	1.0
NPHS1	O60500-1.1	W478Y	Pathogenic	1.0
NPHS1	O60500-1.1	Y479A	Pathogenic	0.667
NPHS1	O60500-1.1	Y479C	Neutral	0.334
NPHS1	O60500-1.1	Y479D	Pathogenic	0.791
NPHS1	O60500-1.1	Y479E	Pathogenic	0.752
NPHS1	O60500-1.1	Y479F	Pathogenic	0.794
NPHS1	O60500-1.1	Y479G	Pathogenic	0.769
NPHS1	O60500-1.1	Y479H	Pathogenic	0.794
NPHS1	O60500-1.1	Y479I	Pathogenic	0.508
NPHS1	O60500-1.1	Y479K	Pathogenic	0.735
NPHS1	O60500-1.1	Y479L	Neutral	0.47
NPHS1	O60500-1.1	Y479M	Neutral	0.306
NPHS1	O60500-1.1	Y479N	Pathogenic	0.796
NPHS1	O60500-1.1	Y479P	Neutral	0.298
NPHS1	O60500-1.1	Y479Q	Pathogenic	0.684
NPHS1	O60500-1.1	Y479R	Pathogenic	0.744
NPHS1	O60500-1.1	Y479S	Pathogenic	0.744
NPHS1	O60500-1.1	Y479T	Pathogenic	0.54
NPHS1	O60500-1.1	Y479V	Neutral	0.404
NPHS1	O60500-1.1	Y479W	Pathogenic	0.882
NPHS1	O60500-1.1	K480A	Pathogenic	1.0
NPHS1	O60500-1.1	K480C	Pathogenic	1.0
NPHS1	O60500-1.1	K480D	Pathogenic	0.998
NPHS1	O60500-1.1	K480E	Pathogenic	0.999
NPHS1	O60500-1.1	K480F	Pathogenic	1.0
NPHS1	O60500-1.1	K480G	Pathogenic	1.0
NPHS1	O60500-1.1	K480H	Pathogenic	0.999
NPHS1	O60500-1.1	K480I	Pathogenic	1.0
NPHS1	O60500-1.1	K480L	Pathogenic	1.0
NPHS1	O60500-1.1	K480M	Pathogenic	1.0
NPHS1	O60500-1.1	K480N	Pathogenic	0.999
NPHS1	O60500-1.1	K480P	Pathogenic	1.0
NPHS1	O60500-1.1	K480Q	Pathogenic	0.999
NPHS1	O60500-1.1	K480R	Pathogenic	0.998
NPHS1	O60500-1.1	K480S	Pathogenic	1.0
NPHS1	O60500-1.1	K480T	Pathogenic	1.0
NPHS1	O60500-1.1	K480V	Pathogenic	1.0
NPHS1	O60500-1.1	K480W	Pathogenic	1.0
NPHS1	O60500-1.1	K480Y	Pathogenic	0.999
NPHS1	O60500-1.1	D481A	Pathogenic	0.765
NPHS1	O60500-1.1	D481C	Pathogenic	0.791
NPHS1	O60500-1.1	D481E	Pathogenic	0.773
NPHS1	O60500-1.1	D481F	Pathogenic	0.969
NPHS1	O60500-1.1	D481G	Pathogenic	0.828
NPHS1	O60500-1.1	D481H	Pathogenic	0.8
NPHS1	O60500-1.1	D481I	Pathogenic	0.961
NPHS1	O60500-1.1	D481K	Pathogenic	0.684
NPHS1	O60500-1.1	D481L	Pathogenic	0.935
NPHS1	O60500-1.1	D481M	Pathogenic	0.914
NPHS1	O60500-1.1	D481N	Pathogenic	0.64
NPHS1	O60500-1.1	D481P	Pathogenic	0.838
NPHS1	O60500-1.1	D481Q	Pathogenic	0.763
NPHS1	O60500-1.1	D481R	Pathogenic	0.669
NPHS1	O60500-1.1	D481S	Pathogenic	0.79
NPHS1	O60500-1.1	D481T	Pathogenic	0.727
NPHS1	O60500-1.1	D481V	Pathogenic	0.869
NPHS1	O60500-1.1	D481W	Pathogenic	0.988
NPHS1	O60500-1.1	D481Y	Pathogenic	0.914
NPHS1	O60500-1.1	S482A	Neutral	0.039
NPHS1	O60500-1.1	S482C	Neutral	0.056
NPHS1	O60500-1.1	S482D	Neutral	0.061
NPHS1	O60500-1.1	S482E	Neutral	0.076
NPHS1	O60500-1.1	S482F	Neutral	0.296
NPHS1	O60500-1.1	S482G	Neutral	0.027
NPHS1	O60500-1.1	S482H	Neutral	0.034
NPHS1	O60500-1.1	S482I	Neutral	0.249
NPHS1	O60500-1.1	S482K	Neutral	0.203
NPHS1	O60500-1.1	S482L	Neutral	0.222
NPHS1	O60500-1.1	S482M	Neutral	0.174
NPHS1	O60500-1.1	S482N	Neutral	0.078
NPHS1	O60500-1.1	S482P	Neutral	0.042
NPHS1	O60500-1.1	S482Q	Neutral	0.047
NPHS1	O60500-1.1	S482R	Neutral	0.192
NPHS1	O60500-1.1	S482T	Neutral	0.05
NPHS1	O60500-1.1	S482V	Neutral	0.081
NPHS1	O60500-1.1	S482W	Pathogenic	0.521
NPHS1	O60500-1.1	S482Y	Neutral	0.124
NPHS1	O60500-1.1	R483A	Pathogenic	0.93
NPHS1	O60500-1.1	R483C	Pathogenic	0.913
NPHS1	O60500-1.1	R483D	Pathogenic	0.505
NPHS1	O60500-1.1	R483E	Pathogenic	0.644
NPHS1	O60500-1.1	R483F	Pathogenic	0.916
NPHS1	O60500-1.1	R483G	Pathogenic	0.899
NPHS1	O60500-1.1	R483H	Pathogenic	0.821
NPHS1	O60500-1.1	R483I	Pathogenic	0.935
NPHS1	O60500-1.1	R483K	Pathogenic	0.563
NPHS1	O60500-1.1	R483L	Pathogenic	0.949
NPHS1	O60500-1.1	R483M	Pathogenic	0.932
NPHS1	O60500-1.1	R483N	Pathogenic	0.722
NPHS1	O60500-1.1	R483P	Pathogenic	0.906
NPHS1	O60500-1.1	R483Q	Pathogenic	0.817
NPHS1	O60500-1.1	R483S	Pathogenic	0.874
NPHS1	O60500-1.1	R483T	Pathogenic	0.87
NPHS1	O60500-1.1	R483V	Pathogenic	0.904
NPHS1	O60500-1.1	R483W	Pathogenic	0.958
NPHS1	O60500-1.1	R483Y	Pathogenic	0.805
NPHS1	O60500-1.1	T484A	Neutral	0.023
NPHS1	O60500-1.1	T484C	Neutral	0.026
NPHS1	O60500-1.1	T484D	Neutral	0.036
NPHS1	O60500-1.1	T484E	Neutral	0.041
NPHS1	O60500-1.1	T484F	Neutral	0.122
NPHS1	O60500-1.1	T484G	Neutral	0.022
NPHS1	O60500-1.1	T484H	Neutral	0.011
NPHS1	O60500-1.1	T484I	Neutral	0.14
NPHS1	O60500-1.1	T484K	Neutral	0.119
NPHS1	O60500-1.1	T484L	Neutral	0.123
NPHS1	O60500-1.1	T484M	Neutral	0.065
NPHS1	O60500-1.1	T484N	Neutral	0.043
NPHS1	O60500-1.1	T484P	Neutral	0.016
NPHS1	O60500-1.1	T484Q	Neutral	0.025
NPHS1	O60500-1.1	T484R	Neutral	0.158
NPHS1	O60500-1.1	T484S	Neutral	0.041
NPHS1	O60500-1.1	T484V	Neutral	0.061
NPHS1	O60500-1.1	T484W	Neutral	0.348
NPHS1	O60500-1.1	T484Y	Neutral	0.044
NPHS1	O60500-1.1	V485A	Pathogenic	0.842
NPHS1	O60500-1.1	V485C	Neutral	0.456
NPHS1	O60500-1.1	V485D	Pathogenic	0.82
NPHS1	O60500-1.1	V485E	Pathogenic	0.815
NPHS1	O60500-1.1	V485F	Pathogenic	0.642
NPHS1	O60500-1.1	V485G	Pathogenic	0.8
NPHS1	O60500-1.1	V485H	Pathogenic	0.537
NPHS1	O60500-1.1	V485I	Pathogenic	0.875
NPHS1	O60500-1.1	V485K	Pathogenic	0.932
NPHS1	O60500-1.1	V485L	Pathogenic	0.73
NPHS1	O60500-1.1	V485M	Pathogenic	0.574
NPHS1	O60500-1.1	V485N	Pathogenic	0.759
NPHS1	O60500-1.1	V485P	Neutral	0.431
NPHS1	O60500-1.1	V485Q	Pathogenic	0.727
NPHS1	O60500-1.1	V485R	Pathogenic	0.927
NPHS1	O60500-1.1	V485S	Pathogenic	0.777
NPHS1	O60500-1.1	V485T	Pathogenic	0.757
NPHS1	O60500-1.1	V485W	Pathogenic	0.757
NPHS1	O60500-1.1	V485Y	Pathogenic	0.564
NPHS1	O60500-1.1	T486A	Neutral	0.022
NPHS1	O60500-1.1	T486C	Neutral	0.025
NPHS1	O60500-1.1	T486D	Neutral	0.035
NPHS1	O60500-1.1	T486E	Neutral	0.039
NPHS1	O60500-1.1	T486F	Neutral	0.116
NPHS1	O60500-1.1	T486G	Neutral	0.021
NPHS1	O60500-1.1	T486H	Neutral	0.011
NPHS1	O60500-1.1	T486I	Neutral	0.134
NPHS1	O60500-1.1	T486K	Neutral	0.113
NPHS1	O60500-1.1	T486L	Neutral	0.117
NPHS1	O60500-1.1	T486M	Neutral	0.062
NPHS1	O60500-1.1	T486N	Neutral	0.041
NPHS1	O60500-1.1	T486P	Neutral	0.016
NPHS1	O60500-1.1	T486Q	Neutral	0.024
NPHS1	O60500-1.1	T486R	Neutral	0.151
NPHS1	O60500-1.1	T486S	Neutral	0.039
NPHS1	O60500-1.1	T486V	Neutral	0.058
NPHS1	O60500-1.1	T486W	Neutral	0.336
NPHS1	O60500-1.1	T486Y	Neutral	0.042
NPHS1	O60500-1.1	E487A	Pathogenic	0.773
NPHS1	O60500-1.1	E487C	Pathogenic	0.641
NPHS1	O60500-1.1	E487D	Pathogenic	0.656
NPHS1	O60500-1.1	E487F	Pathogenic	0.905
NPHS1	O60500-1.1	E487G	Pathogenic	0.693
NPHS1	O60500-1.1	E487H	Pathogenic	0.642
NPHS1	O60500-1.1	E487I	Pathogenic	0.882
NPHS1	O60500-1.1	E487K	Pathogenic	0.682
NPHS1	O60500-1.1	E487L	Pathogenic	0.865
NPHS1	O60500-1.1	E487M	Pathogenic	0.827
NPHS1	O60500-1.1	E487N	Neutral	0.398
NPHS1	O60500-1.1	E487P	Pathogenic	0.785
NPHS1	O60500-1.1	E487Q	Pathogenic	0.682
NPHS1	O60500-1.1	E487R	Pathogenic	0.666
NPHS1	O60500-1.1	E487S	Pathogenic	0.725
NPHS1	O60500-1.1	E487T	Pathogenic	0.63
NPHS1	O60500-1.1	E487V	Pathogenic	0.782
NPHS1	O60500-1.1	E487W	Pathogenic	0.973
NPHS1	O60500-1.1	E487Y	Pathogenic	0.826
NPHS1	O60500-1.1	S488A	Neutral	0.009
NPHS1	O60500-1.1	S488C	Neutral	0.013
NPHS1	O60500-1.1	S488D	Neutral	0.014
NPHS1	O60500-1.1	S488E	Neutral	0.017
NPHS1	O60500-1.1	S488F	Neutral	0.083
NPHS1	O60500-1.1	S488G	Neutral	0.006
NPHS1	O60500-1.1	S488H	Neutral	0.008
NPHS1	O60500-1.1	S488I	Neutral	0.067
NPHS1	O60500-1.1	S488K	Neutral	0.052
NPHS1	O60500-1.1	S488L	Neutral	0.058
NPHS1	O60500-1.1	S488M	Neutral	0.044
NPHS1	O60500-1.1	S488N	Neutral	0.018
NPHS1	O60500-1.1	S488P	Neutral	0.009
NPHS1	O60500-1.1	S488Q	Neutral	0.011
NPHS1	O60500-1.1	S488R	Neutral	0.049
NPHS1	O60500-1.1	S488T	Neutral	0.011
NPHS1	O60500-1.1	S488V	Neutral	0.019
NPHS1	O60500-1.1	S488W	Neutral	0.19
NPHS1	O60500-1.1	S488Y	Neutral	0.03
NPHS1	O60500-1.1	R489A	Pathogenic	0.938
NPHS1	O60500-1.1	R489C	Pathogenic	0.922
NPHS1	O60500-1.1	R489D	Pathogenic	0.535
NPHS1	O60500-1.1	R489E	Pathogenic	0.67
NPHS1	O60500-1.1	R489F	Pathogenic	0.925
NPHS1	O60500-1.1	R489G	Pathogenic	0.909
NPHS1	O60500-1.1	R489H	Pathogenic	0.838
NPHS1	O60500-1.1	R489I	Pathogenic	0.942
NPHS1	O60500-1.1	R489K	Pathogenic	0.592
NPHS1	O60500-1.1	R489L	Pathogenic	0.954
NPHS1	O60500-1.1	R489M	Pathogenic	0.939
NPHS1	O60500-1.1	R489N	Pathogenic	0.745
NPHS1	O60500-1.1	R489P	Pathogenic	0.915
NPHS1	O60500-1.1	R489Q	Pathogenic	0.834
NPHS1	O60500-1.1	R489S	Pathogenic	0.886
NPHS1	O60500-1.1	R489T	Pathogenic	0.883
NPHS1	O60500-1.1	R489V	Pathogenic	0.914
NPHS1	O60500-1.1	R489W	Pathogenic	0.962
NPHS1	O60500-1.1	R489Y	Pathogenic	0.822
NPHS1	O60500-1.1	L490A	Neutral	0.018
NPHS1	O60500-1.1	L490C	Neutral	0.004
NPHS1	O60500-1.1	L490D	Neutral	0.015
NPHS1	O60500-1.1	L490E	Neutral	0.012
NPHS1	O60500-1.1	L490F	Neutral	0.001
NPHS1	O60500-1.1	L490G	Neutral	0.013
NPHS1	O60500-1.1	L490H	Neutral	0.003
NPHS1	O60500-1.1	L490I	Neutral	0.002
NPHS1	O60500-1.1	L490K	Neutral	0.028
NPHS1	O60500-1.1	L490M	Neutral	0.004
NPHS1	O60500-1.1	L490N	Neutral	0.016
NPHS1	O60500-1.1	L490P	Neutral	0.003
NPHS1	O60500-1.1	L490Q	Neutral	0.009
NPHS1	O60500-1.1	L490R	Neutral	0.038
NPHS1	O60500-1.1	L490S	Neutral	0.017
NPHS1	O60500-1.1	L490T	Neutral	0.011
NPHS1	O60500-1.1	L490V	Neutral	0.004
NPHS1	O60500-1.1	L490W	Neutral	0.002
NPHS1	O60500-1.1	L490Y	Neutral	0.003
NPHS1	O60500-1.1	P491A	Neutral	0.138
NPHS1	O60500-1.1	P491C	Neutral	0.036
NPHS1	O60500-1.1	P491D	Neutral	0.321
NPHS1	O60500-1.1	P491E	Neutral	0.373
NPHS1	O60500-1.1	P491F	Neutral	0.178
NPHS1	O60500-1.1	P491G	Neutral	0.21
NPHS1	O60500-1.1	P491H	Neutral	0.136
NPHS1	O60500-1.1	P491I	Neutral	0.203
NPHS1	O60500-1.1	P491K	Pathogenic	0.65
NPHS1	O60500-1.1	P491L	Neutral	0.179
NPHS1	O60500-1.1	P491M	Neutral	0.139
NPHS1	O60500-1.1	P491N	Neutral	0.217
NPHS1	O60500-1.1	P491Q	Neutral	0.264
NPHS1	O60500-1.1	P491R	Pathogenic	0.634
NPHS1	O60500-1.1	P491S	Neutral	0.188
NPHS1	O60500-1.1	P491T	Neutral	0.097
NPHS1	O60500-1.1	P491V	Neutral	0.092
NPHS1	O60500-1.1	P491W	Neutral	0.455
NPHS1	O60500-1.1	P491Y	Neutral	0.098
NPHS1	O60500-1.1	Q492A	Pathogenic	0.8
NPHS1	O60500-1.1	Q492C	Pathogenic	0.759
NPHS1	O60500-1.1	Q492D	Pathogenic	0.778
NPHS1	O60500-1.1	Q492E	Pathogenic	0.807
NPHS1	O60500-1.1	Q492F	Pathogenic	0.898
NPHS1	O60500-1.1	Q492G	Pathogenic	0.727
NPHS1	O60500-1.1	Q492H	Pathogenic	0.625
NPHS1	O60500-1.1	Q492I	Pathogenic	0.874
NPHS1	O60500-1.1	Q492K	Pathogenic	0.874
NPHS1	O60500-1.1	Q492L	Pathogenic	0.899
NPHS1	O60500-1.1	Q492M	Pathogenic	0.908
NPHS1	O60500-1.1	Q492N	Pathogenic	0.708
NPHS1	O60500-1.1	Q492P	Pathogenic	0.811
NPHS1	O60500-1.1	Q492R	Pathogenic	0.906
NPHS1	O60500-1.1	Q492S	Pathogenic	0.757
NPHS1	O60500-1.1	Q492T	Pathogenic	0.668
NPHS1	O60500-1.1	Q492V	Pathogenic	0.809
NPHS1	O60500-1.1	Q492W	Pathogenic	0.981
NPHS1	O60500-1.1	Q492Y	Pathogenic	0.868
NPHS1	O60500-1.1	E493A	Pathogenic	0.689
NPHS1	O60500-1.1	E493C	Pathogenic	0.538
NPHS1	O60500-1.1	E493D	Pathogenic	0.554
NPHS1	O60500-1.1	E493F	Pathogenic	0.861
NPHS1	O60500-1.1	E493G	Pathogenic	0.596
NPHS1	O60500-1.1	E493H	Pathogenic	0.539
NPHS1	O60500-1.1	E493I	Pathogenic	0.83
NPHS1	O60500-1.1	E493K	Pathogenic	0.583
NPHS1	O60500-1.1	E493L	Pathogenic	0.807
NPHS1	O60500-1.1	E493M	Pathogenic	0.757
NPHS1	O60500-1.1	E493N	Neutral	0.301
NPHS1	O60500-1.1	E493P	Pathogenic	0.704
NPHS1	O60500-1.1	E493Q	Pathogenic	0.583
NPHS1	O60500-1.1	E493R	Pathogenic	0.566
NPHS1	O60500-1.1	E493S	Pathogenic	0.632
NPHS1	O60500-1.1	E493T	Pathogenic	0.527
NPHS1	O60500-1.1	E493V	Pathogenic	0.701
NPHS1	O60500-1.1	E493W	Pathogenic	0.96
NPHS1	O60500-1.1	E493Y	Pathogenic	0.756
NPHS1	O60500-1.1	S494A	Neutral	0.005
NPHS1	O60500-1.1	S494C	Neutral	0.008
NPHS1	O60500-1.1	S494D	Neutral	0.008
NPHS1	O60500-1.1	S494E	Neutral	0.01
NPHS1	O60500-1.1	S494F	Neutral	0.051
NPHS1	O60500-1.1	S494G	Neutral	0.003
NPHS1	O60500-1.1	S494H	Neutral	0.005
NPHS1	O60500-1.1	S494I	Neutral	0.041
NPHS1	O60500-1.1	S494K	Neutral	0.032
NPHS1	O60500-1.1	S494L	Neutral	0.035
NPHS1	O60500-1.1	S494M	Neutral	0.026
NPHS1	O60500-1.1	S494N	Neutral	0.011
NPHS1	O60500-1.1	S494P	Neutral	0.006
NPHS1	O60500-1.1	S494Q	Neutral	0.006
NPHS1	O60500-1.1	S494R	Neutral	0.03
NPHS1	O60500-1.1	S494T	Neutral	0.007
NPHS1	O60500-1.1	S494V	Neutral	0.011
NPHS1	O60500-1.1	S494W	Neutral	0.123
NPHS1	O60500-1.1	S494Y	Neutral	0.018
NPHS1	O60500-1.1	R495A	Pathogenic	0.909
NPHS1	O60500-1.1	R495C	Pathogenic	0.887
NPHS1	O60500-1.1	R495D	Neutral	0.433
NPHS1	O60500-1.1	R495E	Pathogenic	0.575
NPHS1	O60500-1.1	R495F	Pathogenic	0.891
NPHS1	O60500-1.1	R495G	Pathogenic	0.869
NPHS1	O60500-1.1	R495H	Pathogenic	0.775
NPHS1	O60500-1.1	R495I	Pathogenic	0.915
NPHS1	O60500-1.1	R495K	Neutral	0.491
NPHS1	O60500-1.1	R495L	Pathogenic	0.933
NPHS1	O60500-1.1	R495M	Pathogenic	0.911
NPHS1	O60500-1.1	R495N	Pathogenic	0.66
NPHS1	O60500-1.1	R495P	Pathogenic	0.878
NPHS1	O60500-1.1	R495Q	Pathogenic	0.77
NPHS1	O60500-1.1	R495S	Pathogenic	0.839
NPHS1	O60500-1.1	R495T	Pathogenic	0.834
NPHS1	O60500-1.1	R495V	Pathogenic	0.876
NPHS1	O60500-1.1	R495W	Pathogenic	0.945
NPHS1	O60500-1.1	R495Y	Pathogenic	0.755
NPHS1	O60500-1.1	R496A	Pathogenic	0.717
NPHS1	O60500-1.1	R496C	Pathogenic	0.665
NPHS1	O60500-1.1	R496D	Neutral	0.163
NPHS1	O60500-1.1	R496E	Neutral	0.256
NPHS1	O60500-1.1	R496F	Pathogenic	0.675
NPHS1	O60500-1.1	R496G	Pathogenic	0.628
NPHS1	O60500-1.1	R496H	Neutral	0.466
NPHS1	O60500-1.1	R496I	Pathogenic	0.733
NPHS1	O60500-1.1	R496K	Neutral	0.197
NPHS1	O60500-1.1	R496L	Pathogenic	0.779
NPHS1	O60500-1.1	R496M	Pathogenic	0.723
NPHS1	O60500-1.1	R496N	Neutral	0.33
NPHS1	O60500-1.1	R496P	Pathogenic	0.645
NPHS1	O60500-1.1	R496Q	Neutral	0.459
NPHS1	O60500-1.1	R496S	Pathogenic	0.569
NPHS1	O60500-1.1	R496T	Pathogenic	0.56
NPHS1	O60500-1.1	R496V	Pathogenic	0.643
NPHS1	O60500-1.1	R496W	Pathogenic	0.812
NPHS1	O60500-1.1	R496Y	Neutral	0.439
NPHS1	O60500-1.1	V497A	Pathogenic	0.709
NPHS1	O60500-1.1	V497C	Neutral	0.276
NPHS1	O60500-1.1	V497D	Pathogenic	0.674
NPHS1	O60500-1.1	V497E	Pathogenic	0.667
NPHS1	O60500-1.1	V497F	Neutral	0.45
NPHS1	O60500-1.1	V497G	Pathogenic	0.645
NPHS1	O60500-1.1	V497H	Neutral	0.346
NPHS1	O60500-1.1	V497I	Pathogenic	0.761
NPHS1	O60500-1.1	V497K	Pathogenic	0.862
NPHS1	O60500-1.1	V497L	Pathogenic	0.552
NPHS1	O60500-1.1	V497M	Neutral	0.38
NPHS1	O60500-1.1	V497N	Pathogenic	0.589
NPHS1	O60500-1.1	V497P	Neutral	0.257
NPHS1	O60500-1.1	V497Q	Pathogenic	0.548
NPHS1	O60500-1.1	V497R	Pathogenic	0.853
NPHS1	O60500-1.1	V497S	Pathogenic	0.613
NPHS1	O60500-1.1	V497T	Pathogenic	0.587
NPHS1	O60500-1.1	V497W	Pathogenic	0.586
NPHS1	O60500-1.1	V497Y	Neutral	0.371
NPHS1	O60500-1.1	H498A	Neutral	0.009
NPHS1	O60500-1.1	H498C	Neutral	0.01
NPHS1	O60500-1.1	H498D	Neutral	0.021
NPHS1	O60500-1.1	H498E	Neutral	0.017
NPHS1	O60500-1.1	H498F	Neutral	0.05
NPHS1	O60500-1.1	H498G	Neutral	0.013
NPHS1	O60500-1.1	H498I	Neutral	0.018
NPHS1	O60500-1.1	H498K	Neutral	0.023
NPHS1	O60500-1.1	H498L	Neutral	0.016
NPHS1	O60500-1.1	H498M	Neutral	0.012
NPHS1	O60500-1.1	H498N	Neutral	0.032
NPHS1	O60500-1.1	H498P	Neutral	0.009
NPHS1	O60500-1.1	H498Q	Neutral	0.008
NPHS1	O60500-1.1	H498R	Neutral	0.047
NPHS1	O60500-1.1	H498S	Neutral	0.011
NPHS1	O60500-1.1	H498T	Neutral	0.004
NPHS1	O60500-1.1	H498V	Neutral	0.009
NPHS1	O60500-1.1	H498W	Neutral	0.119
NPHS1	O60500-1.1	H498Y	Neutral	0.055
NPHS1	O60500-1.1	L499A	Pathogenic	0.607
NPHS1	O60500-1.1	L499C	Neutral	0.265
NPHS1	O60500-1.1	L499D	Pathogenic	0.568
NPHS1	O60500-1.1	L499E	Pathogenic	0.512
NPHS1	O60500-1.1	L499F	Neutral	0.1
NPHS1	O60500-1.1	L499G	Pathogenic	0.536
NPHS1	O60500-1.1	L499H	Neutral	0.213
NPHS1	O60500-1.1	L499I	Neutral	0.163
NPHS1	O60500-1.1	L499K	Pathogenic	0.707
NPHS1	O60500-1.1	L499M	Neutral	0.252
NPHS1	O60500-1.1	L499N	Pathogenic	0.575
NPHS1	O60500-1.1	L499P	Neutral	0.18
NPHS1	O60500-1.1	L499Q	Neutral	0.428
NPHS1	O60500-1.1	L499R	Pathogenic	0.77
NPHS1	O60500-1.1	L499S	Pathogenic	0.6
NPHS1	O60500-1.1	L499T	Neutral	0.474
NPHS1	O60500-1.1	L499V	Neutral	0.266
NPHS1	O60500-1.1	L499W	Neutral	0.162
NPHS1	O60500-1.1	L499Y	Neutral	0.185
NPHS1	O60500-1.1	G500A	Pathogenic	0.685
NPHS1	O60500-1.1	G500C	Pathogenic	0.737
NPHS1	O60500-1.1	G500D	Pathogenic	0.836
NPHS1	O60500-1.1	G500E	Pathogenic	0.812
NPHS1	O60500-1.1	G500F	Pathogenic	0.967
NPHS1	O60500-1.1	G500H	Pathogenic	0.715
NPHS1	O60500-1.1	G500I	Pathogenic	0.94
NPHS1	O60500-1.1	G500K	Pathogenic	0.931
NPHS1	O60500-1.1	G500L	Pathogenic	0.931
NPHS1	O60500-1.1	G500M	Pathogenic	0.909
NPHS1	O60500-1.1	G500N	Pathogenic	0.87
NPHS1	O60500-1.1	G500P	Pathogenic	0.756
NPHS1	O60500-1.1	G500Q	Pathogenic	0.723
NPHS1	O60500-1.1	G500R	Pathogenic	0.949
NPHS1	O60500-1.1	G500S	Pathogenic	0.626
NPHS1	O60500-1.1	G500T	Pathogenic	0.626
NPHS1	O60500-1.1	G500V	Pathogenic	0.862
NPHS1	O60500-1.1	G500W	Pathogenic	0.994
NPHS1	O60500-1.1	G500Y	Pathogenic	0.909
NPHS1	O60500-1.1	S501A	Neutral	0.053
NPHS1	O60500-1.1	S501C	Neutral	0.074
NPHS1	O60500-1.1	S501D	Neutral	0.081
NPHS1	O60500-1.1	S501E	Neutral	0.1
NPHS1	O60500-1.1	S501F	Neutral	0.363
NPHS1	O60500-1.1	S501G	Neutral	0.036
NPHS1	O60500-1.1	S501H	Neutral	0.046
NPHS1	O60500-1.1	S501I	Neutral	0.31
NPHS1	O60500-1.1	S501K	Neutral	0.257
NPHS1	O60500-1.1	S501L	Neutral	0.278
NPHS1	O60500-1.1	S501M	Neutral	0.222
NPHS1	O60500-1.1	S501N	Neutral	0.103
NPHS1	O60500-1.1	S501P	Neutral	0.056
NPHS1	O60500-1.1	S501Q	Neutral	0.063
NPHS1	O60500-1.1	S501R	Neutral	0.244
NPHS1	O60500-1.1	S501T	Neutral	0.067
NPHS1	O60500-1.1	S501V	Neutral	0.107
NPHS1	O60500-1.1	S501W	Pathogenic	0.595
NPHS1	O60500-1.1	S501Y	Neutral	0.161
NPHS1	O60500-1.1	V502A	Neutral	0.074
NPHS1	O60500-1.1	V502C	Neutral	0.012
NPHS1	O60500-1.1	V502D	Neutral	0.064
NPHS1	O60500-1.1	V502E	Neutral	0.062
NPHS1	O60500-1.1	V502F	Neutral	0.026
NPHS1	O60500-1.1	V502G	Neutral	0.057
NPHS1	O60500-1.1	V502H	Neutral	0.017
NPHS1	O60500-1.1	V502I	Neutral	0.095
NPHS1	O60500-1.1	V502K	Neutral	0.171
NPHS1	O60500-1.1	V502L	Neutral	0.039
NPHS1	O60500-1.1	V502M	Neutral	0.02
NPHS1	O60500-1.1	V502N	Neutral	0.045
NPHS1	O60500-1.1	V502P	Neutral	0.011
NPHS1	O60500-1.1	V502Q	Neutral	0.038
NPHS1	O60500-1.1	V502R	Neutral	0.161
NPHS1	O60500-1.1	V502S	Neutral	0.05
NPHS1	O60500-1.1	V502T	Neutral	0.045
NPHS1	O60500-1.1	V502W	Neutral	0.045
NPHS1	O60500-1.1	V502Y	Neutral	0.019
NPHS1	O60500-1.1	E503A	Pathogenic	0.599
NPHS1	O60500-1.1	E503C	Neutral	0.44
NPHS1	O60500-1.1	E503D	Neutral	0.456
NPHS1	O60500-1.1	E503F	Pathogenic	0.807
NPHS1	O60500-1.1	E503G	Neutral	0.498
NPHS1	O60500-1.1	E503H	Neutral	0.44
NPHS1	O60500-1.1	E503I	Pathogenic	0.767
NPHS1	O60500-1.1	E503K	Neutral	0.485
NPHS1	O60500-1.1	E503L	Pathogenic	0.738
NPHS1	O60500-1.1	E503M	Pathogenic	0.677
NPHS1	O60500-1.1	E503N	Neutral	0.225
NPHS1	O60500-1.1	E503P	Pathogenic	0.615
NPHS1	O60500-1.1	E503Q	Neutral	0.485
NPHS1	O60500-1.1	E503R	Neutral	0.467
NPHS1	O60500-1.1	E503S	Pathogenic	0.537
NPHS1	O60500-1.1	E503T	Neutral	0.428
NPHS1	O60500-1.1	E503V	Pathogenic	0.612
NPHS1	O60500-1.1	E503W	Pathogenic	0.941
NPHS1	O60500-1.1	E503Y	Pathogenic	0.676
NPHS1	O60500-1.1	K504A	Pathogenic	0.985
NPHS1	O60500-1.1	K504C	Pathogenic	0.98
NPHS1	O60500-1.1	K504D	Pathogenic	0.88
NPHS1	O60500-1.1	K504E	Pathogenic	0.928
NPHS1	O60500-1.1	K504F	Pathogenic	0.981
NPHS1	O60500-1.1	K504G	Pathogenic	0.977
NPHS1	O60500-1.1	K504H	Pathogenic	0.937
NPHS1	O60500-1.1	K504I	Pathogenic	0.986
NPHS1	O60500-1.1	K504L	Pathogenic	0.989
NPHS1	O60500-1.1	K504M	Pathogenic	0.985
NPHS1	O60500-1.1	K504N	Pathogenic	0.926
NPHS1	O60500-1.1	K504P	Pathogenic	0.986
NPHS1	O60500-1.1	K504Q	Pathogenic	0.955
NPHS1	O60500-1.1	K504R	Pathogenic	0.896
NPHS1	O60500-1.1	K504S	Pathogenic	0.98
NPHS1	O60500-1.1	K504T	Pathogenic	0.97
NPHS1	O60500-1.1	K504V	Pathogenic	0.985
NPHS1	O60500-1.1	K504W	Pathogenic	0.995
NPHS1	O60500-1.1	K504Y	Pathogenic	0.963
NPHS1	O60500-1.1	S505A	Pathogenic	0.839
NPHS1	O60500-1.1	S505C	Pathogenic	0.883
NPHS1	O60500-1.1	S505D	Pathogenic	0.892
NPHS1	O60500-1.1	S505E	Pathogenic	0.913
NPHS1	O60500-1.1	S505F	Pathogenic	0.982
NPHS1	O60500-1.1	S505G	Pathogenic	0.776
NPHS1	O60500-1.1	S505H	Pathogenic	0.82
NPHS1	O60500-1.1	S505I	Pathogenic	0.977
NPHS1	O60500-1.1	S505K	Pathogenic	0.97
NPHS1	O60500-1.1	S505L	Pathogenic	0.973
NPHS1	O60500-1.1	S505M	Pathogenic	0.964
NPHS1	O60500-1.1	S505N	Pathogenic	0.915
NPHS1	O60500-1.1	S505P	Pathogenic	0.849
NPHS1	O60500-1.1	S505Q	Pathogenic	0.863
NPHS1	O60500-1.1	S505R	Pathogenic	0.968
NPHS1	O60500-1.1	S505T	Pathogenic	0.871
NPHS1	O60500-1.1	S505V	Pathogenic	0.918
NPHS1	O60500-1.1	S505W	Pathogenic	0.993
NPHS1	O60500-1.1	S505Y	Pathogenic	0.947
NPHS1	O60500-1.1	G506A	Pathogenic	0.852
NPHS1	O60500-1.1	G506C	Pathogenic	0.881
NPHS1	O60500-1.1	G506D	Pathogenic	0.931
NPHS1	O60500-1.1	G506E	Pathogenic	0.919
NPHS1	O60500-1.1	G506F	Pathogenic	0.987
NPHS1	O60500-1.1	G506H	Pathogenic	0.869
NPHS1	O60500-1.1	G506I	Pathogenic	0.976
NPHS1	O60500-1.1	G506K	Pathogenic	0.973
NPHS1	O60500-1.1	G506L	Pathogenic	0.973
NPHS1	O60500-1.1	G506M	Pathogenic	0.963
NPHS1	O60500-1.1	G506N	Pathogenic	0.946
NPHS1	O60500-1.1	G506P	Pathogenic	0.891
NPHS1	O60500-1.1	G506Q	Pathogenic	0.873
NPHS1	O60500-1.1	G506R	Pathogenic	0.98
NPHS1	O60500-1.1	G506S	Pathogenic	0.816
NPHS1	O60500-1.1	G506T	Pathogenic	0.816
NPHS1	O60500-1.1	G506V	Pathogenic	0.943
NPHS1	O60500-1.1	G506W	Pathogenic	0.998
NPHS1	O60500-1.1	G506Y	Pathogenic	0.963
NPHS1	O60500-1.1	S507A	Neutral	0.164
NPHS1	O60500-1.1	S507C	Neutral	0.221
NPHS1	O60500-1.1	S507D	Neutral	0.238
NPHS1	O60500-1.1	S507E	Neutral	0.282
NPHS1	O60500-1.1	S507F	Pathogenic	0.668
NPHS1	O60500-1.1	S507G	Neutral	0.115
NPHS1	O60500-1.1	S507H	Neutral	0.146
NPHS1	O60500-1.1	S507I	Pathogenic	0.614
NPHS1	O60500-1.1	S507K	Pathogenic	0.55
NPHS1	O60500-1.1	S507L	Pathogenic	0.577
NPHS1	O60500-1.1	S507M	Pathogenic	0.503
NPHS1	O60500-1.1	S507N	Neutral	0.289
NPHS1	O60500-1.1	S507P	Neutral	0.174
NPHS1	O60500-1.1	S507Q	Neutral	0.191
NPHS1	O60500-1.1	S507R	Pathogenic	0.533
NPHS1	O60500-1.1	S507T	Neutral	0.202
NPHS1	O60500-1.1	S507V	Neutral	0.297
NPHS1	O60500-1.1	S507W	Pathogenic	0.839
NPHS1	O60500-1.1	S507Y	Neutral	0.404
NPHS1	O60500-1.1	T508A	Neutral	0.189
NPHS1	O60500-1.1	T508C	Neutral	0.214
NPHS1	O60500-1.1	T508D	Neutral	0.274
NPHS1	O60500-1.1	T508E	Neutral	0.302
NPHS1	O60500-1.1	T508F	Pathogenic	0.581
NPHS1	O60500-1.1	T508G	Neutral	0.182
NPHS1	O60500-1.1	T508H	Neutral	0.102
NPHS1	O60500-1.1	T508I	Pathogenic	0.619
NPHS1	O60500-1.1	T508K	Pathogenic	0.574
NPHS1	O60500-1.1	T508L	Pathogenic	0.583
NPHS1	O60500-1.1	T508M	Neutral	0.41
NPHS1	O60500-1.1	T508N	Neutral	0.31
NPHS1	O60500-1.1	T508P	Neutral	0.143
NPHS1	O60500-1.1	T508Q	Neutral	0.207
NPHS1	O60500-1.1	T508R	Pathogenic	0.652
NPHS1	O60500-1.1	T508S	Neutral	0.302
NPHS1	O60500-1.1	T508V	Neutral	0.393
NPHS1	O60500-1.1	T508W	Pathogenic	0.842
NPHS1	O60500-1.1	T508Y	Neutral	0.317
NPHS1	O60500-1.1	F509A	Pathogenic	0.981
NPHS1	O60500-1.1	F509C	Pathogenic	0.924
NPHS1	O60500-1.1	F509D	Pathogenic	0.99
NPHS1	O60500-1.1	F509E	Pathogenic	0.981
NPHS1	O60500-1.1	F509G	Pathogenic	0.989
NPHS1	O60500-1.1	F509H	Pathogenic	0.968
NPHS1	O60500-1.1	F509I	Pathogenic	0.773
NPHS1	O60500-1.1	F509K	Pathogenic	0.98
NPHS1	O60500-1.1	F509L	Pathogenic	0.791
NPHS1	O60500-1.1	F509M	Pathogenic	0.884
NPHS1	O60500-1.1	F509N	Pathogenic	0.986
NPHS1	O60500-1.1	F509P	Pathogenic	0.881
NPHS1	O60500-1.1	F509Q	Pathogenic	0.962
NPHS1	O60500-1.1	F509R	Pathogenic	0.985
NPHS1	O60500-1.1	F509S	Pathogenic	0.987
NPHS1	O60500-1.1	F509T	Pathogenic	0.968
NPHS1	O60500-1.1	F509V	Pathogenic	0.891
NPHS1	O60500-1.1	F509W	Pathogenic	0.937
NPHS1	O60500-1.1	F509Y	Pathogenic	0.971
NPHS1	O60500-1.1	S510A	Pathogenic	0.778
NPHS1	O60500-1.1	S510C	Pathogenic	0.835
NPHS1	O60500-1.1	S510D	Pathogenic	0.848
NPHS1	O60500-1.1	S510E	Pathogenic	0.875
NPHS1	O60500-1.1	S510F	Pathogenic	0.973
NPHS1	O60500-1.1	S510G	Pathogenic	0.7
NPHS1	O60500-1.1	S510H	Pathogenic	0.753
NPHS1	O60500-1.1	S510I	Pathogenic	0.966
NPHS1	O60500-1.1	S510K	Pathogenic	0.956
NPHS1	O60500-1.1	S510L	Pathogenic	0.961
NPHS1	O60500-1.1	S510M	Pathogenic	0.948
NPHS1	O60500-1.1	S510N	Pathogenic	0.879
NPHS1	O60500-1.1	S510P	Pathogenic	0.79
NPHS1	O60500-1.1	S510Q	Pathogenic	0.809
NPHS1	O60500-1.1	S510R	Pathogenic	0.953
NPHS1	O60500-1.1	S510T	Pathogenic	0.819
NPHS1	O60500-1.1	S510V	Pathogenic	0.883
NPHS1	O60500-1.1	S510W	Pathogenic	0.989
NPHS1	O60500-1.1	S510Y	Pathogenic	0.924
NPHS1	O60500-1.1	R511A	Pathogenic	0.992
NPHS1	O60500-1.1	R511C	Pathogenic	0.99
NPHS1	O60500-1.1	R511D	Pathogenic	0.908
NPHS1	O60500-1.1	R511E	Pathogenic	0.946
NPHS1	O60500-1.1	R511F	Pathogenic	0.991
NPHS1	O60500-1.1	R511G	Pathogenic	0.989
NPHS1	O60500-1.1	R511H	Pathogenic	0.978
NPHS1	O60500-1.1	R511I	Pathogenic	0.993
NPHS1	O60500-1.1	R511K	Pathogenic	0.926
NPHS1	O60500-1.1	R511L	Pathogenic	0.994
NPHS1	O60500-1.1	R511M	Pathogenic	0.993
NPHS1	O60500-1.1	R511N	Pathogenic	0.962
NPHS1	O60500-1.1	R511P	Pathogenic	0.989
NPHS1	O60500-1.1	R511Q	Pathogenic	0.977
NPHS1	O60500-1.1	R511S	Pathogenic	0.985
NPHS1	O60500-1.1	R511T	Pathogenic	0.985
NPHS1	O60500-1.1	R511V	Pathogenic	0.989
NPHS1	O60500-1.1	R511W	Pathogenic	0.995
NPHS1	O60500-1.1	R511Y	Pathogenic	0.976
NPHS1	O60500-1.1	E512A	Pathogenic	0.984
NPHS1	O60500-1.1	E512C	Pathogenic	0.969
NPHS1	O60500-1.1	E512D	Pathogenic	0.971
NPHS1	O60500-1.1	E512F	Pathogenic	0.994
NPHS1	O60500-1.1	E512G	Pathogenic	0.975
NPHS1	O60500-1.1	E512H	Pathogenic	0.969
NPHS1	O60500-1.1	E512I	Pathogenic	0.992
NPHS1	O60500-1.1	E512K	Pathogenic	0.974
NPHS1	O60500-1.1	E512L	Pathogenic	0.991
NPHS1	O60500-1.1	E512M	Pathogenic	0.988
NPHS1	O60500-1.1	E512N	Pathogenic	0.921
NPHS1	O60500-1.1	E512P	Pathogenic	0.985
NPHS1	O60500-1.1	E512Q	Pathogenic	0.974
NPHS1	O60500-1.1	E512R	Pathogenic	0.972
NPHS1	O60500-1.1	E512S	Pathogenic	0.979
NPHS1	O60500-1.1	E512T	Pathogenic	0.968
NPHS1	O60500-1.1	E512V	Pathogenic	0.984
NPHS1	O60500-1.1	E512W	Pathogenic	0.998
NPHS1	O60500-1.1	E512Y	Pathogenic	0.988
NPHS1	O60500-1.1	L513A	Pathogenic	0.978
NPHS1	O60500-1.1	L513C	Pathogenic	0.913
NPHS1	O60500-1.1	L513D	Pathogenic	0.974
NPHS1	O60500-1.1	L513E	Pathogenic	0.968
NPHS1	O60500-1.1	L513F	Pathogenic	0.763
NPHS1	O60500-1.1	L513G	Pathogenic	0.971
NPHS1	O60500-1.1	L513H	Pathogenic	0.887
NPHS1	O60500-1.1	L513I	Pathogenic	0.85
NPHS1	O60500-1.1	L513K	Pathogenic	0.986
NPHS1	O60500-1.1	L513M	Pathogenic	0.907
NPHS1	O60500-1.1	L513N	Pathogenic	0.975
NPHS1	O60500-1.1	L513P	Pathogenic	0.864
NPHS1	O60500-1.1	L513Q	Pathogenic	0.956
NPHS1	O60500-1.1	L513R	Pathogenic	0.99
NPHS1	O60500-1.1	L513S	Pathogenic	0.978
NPHS1	O60500-1.1	L513T	Pathogenic	0.963
NPHS1	O60500-1.1	L513V	Pathogenic	0.913
NPHS1	O60500-1.1	L513W	Pathogenic	0.848
NPHS1	O60500-1.1	L513Y	Pathogenic	0.868
NPHS1	O60500-1.1	V514A	Neutral	0.404
NPHS1	O60500-1.1	V514C	Neutral	0.096
NPHS1	O60500-1.1	V514D	Neutral	0.366
NPHS1	O60500-1.1	V514E	Neutral	0.358
NPHS1	O60500-1.1	V514F	Neutral	0.186
NPHS1	O60500-1.1	V514G	Neutral	0.336
NPHS1	O60500-1.1	V514H	Neutral	0.128
NPHS1	O60500-1.1	V514I	Neutral	0.471
NPHS1	O60500-1.1	V514K	Pathogenic	0.635
NPHS1	O60500-1.1	V514L	Neutral	0.255
NPHS1	O60500-1.1	V514M	Neutral	0.146
NPHS1	O60500-1.1	V514N	Neutral	0.285
NPHS1	O60500-1.1	V514P	Neutral	0.088
NPHS1	O60500-1.1	V514Q	Neutral	0.252
NPHS1	O60500-1.1	V514R	Pathogenic	0.619
NPHS1	O60500-1.1	V514S	Neutral	0.307
NPHS1	O60500-1.1	V514T	Neutral	0.284
NPHS1	O60500-1.1	V514W	Neutral	0.283
NPHS1	O60500-1.1	V514Y	Neutral	0.141
NPHS1	O60500-1.1	L515A	Pathogenic	0.976
NPHS1	O60500-1.1	L515C	Pathogenic	0.904
NPHS1	O60500-1.1	L515D	Pathogenic	0.972
NPHS1	O60500-1.1	L515E	Pathogenic	0.965
NPHS1	O60500-1.1	L515F	Pathogenic	0.744
NPHS1	O60500-1.1	L515G	Pathogenic	0.968
NPHS1	O60500-1.1	L515H	Pathogenic	0.876
NPHS1	O60500-1.1	L515I	Pathogenic	0.836
NPHS1	O60500-1.1	L515K	Pathogenic	0.984
NPHS1	O60500-1.1	L515M	Pathogenic	0.898
NPHS1	O60500-1.1	L515N	Pathogenic	0.972
NPHS1	O60500-1.1	L515P	Pathogenic	0.851
NPHS1	O60500-1.1	L515Q	Pathogenic	0.951
NPHS1	O60500-1.1	L515R	Pathogenic	0.989
NPHS1	O60500-1.1	L515S	Pathogenic	0.975
NPHS1	O60500-1.1	L515T	Pathogenic	0.959
NPHS1	O60500-1.1	L515V	Pathogenic	0.904
NPHS1	O60500-1.1	L515W	Pathogenic	0.834
NPHS1	O60500-1.1	L515Y	Pathogenic	0.855
NPHS1	O60500-1.1	V516A	Neutral	0.066
NPHS1	O60500-1.1	V516C	Neutral	0.011
NPHS1	O60500-1.1	V516D	Neutral	0.057
NPHS1	O60500-1.1	V516E	Neutral	0.055
NPHS1	O60500-1.1	V516F	Neutral	0.023
NPHS1	O60500-1.1	V516G	Neutral	0.051
NPHS1	O60500-1.1	V516H	Neutral	0.015
NPHS1	O60500-1.1	V516I	Neutral	0.085
NPHS1	O60500-1.1	V516K	Neutral	0.155
NPHS1	O60500-1.1	V516L	Neutral	0.035
NPHS1	O60500-1.1	V516M	Neutral	0.018
NPHS1	O60500-1.1	V516N	Neutral	0.04
NPHS1	O60500-1.1	V516P	Neutral	0.01
NPHS1	O60500-1.1	V516Q	Neutral	0.034
NPHS1	O60500-1.1	V516R	Neutral	0.146
NPHS1	O60500-1.1	V516S	Neutral	0.044
NPHS1	O60500-1.1	V516T	Neutral	0.04
NPHS1	O60500-1.1	V516W	Neutral	0.04
NPHS1	O60500-1.1	V516Y	Neutral	0.017
NPHS1	O60500-1.1	T517A	Neutral	0.037
NPHS1	O60500-1.1	T517C	Neutral	0.043
NPHS1	O60500-1.1	T517D	Neutral	0.059
NPHS1	O60500-1.1	T517E	Neutral	0.066
NPHS1	O60500-1.1	T517F	Neutral	0.186
NPHS1	O60500-1.1	T517G	Neutral	0.035
NPHS1	O60500-1.1	T517H	Neutral	0.018
NPHS1	O60500-1.1	T517I	Neutral	0.211
NPHS1	O60500-1.1	T517K	Neutral	0.182
NPHS1	O60500-1.1	T517L	Neutral	0.187
NPHS1	O60500-1.1	T517M	Neutral	0.103
NPHS1	O60500-1.1	T517N	Neutral	0.069
NPHS1	O60500-1.1	T517P	Neutral	0.027
NPHS1	O60500-1.1	T517Q	Neutral	0.041
NPHS1	O60500-1.1	T517R	Neutral	0.236
NPHS1	O60500-1.1	T517S	Neutral	0.066
NPHS1	O60500-1.1	T517V	Neutral	0.096
NPHS1	O60500-1.1	T517W	Neutral	0.468
NPHS1	O60500-1.1	T517Y	Neutral	0.071
NPHS1	O60500-1.1	G518A	Neutral	0.046
NPHS1	O60500-1.1	G518C	Neutral	0.059
NPHS1	O60500-1.1	G518D	Neutral	0.102
NPHS1	O60500-1.1	G518E	Neutral	0.088
NPHS1	O60500-1.1	G518F	Neutral	0.397
NPHS1	O60500-1.1	G518H	Neutral	0.053
NPHS1	O60500-1.1	G518I	Neutral	0.258
NPHS1	O60500-1.1	G518K	Neutral	0.23
NPHS1	O60500-1.1	G518L	Neutral	0.23
NPHS1	O60500-1.1	G518M	Neutral	0.182
NPHS1	O60500-1.1	G518N	Neutral	0.129
NPHS1	O60500-1.1	G518P	Neutral	0.065
NPHS1	O60500-1.1	G518Q	Neutral	0.055
NPHS1	O60500-1.1	G518R	Neutral	0.294
NPHS1	O60500-1.1	G518S	Neutral	0.036
NPHS1	O60500-1.1	G518T	Neutral	0.036
NPHS1	O60500-1.1	G518V	Neutral	0.122
NPHS1	O60500-1.1	G518W	Pathogenic	0.791
NPHS1	O60500-1.1	G518Y	Neutral	0.181
NPHS1	O60500-1.1	P519A	Pathogenic	0.95
NPHS1	O60500-1.1	P519C	Pathogenic	0.815
NPHS1	O60500-1.1	P519D	Pathogenic	0.983
NPHS1	O60500-1.1	P519E	Pathogenic	0.986
NPHS1	O60500-1.1	P519F	Pathogenic	0.963
NPHS1	O60500-1.1	P519G	Pathogenic	0.969
NPHS1	O60500-1.1	P519H	Pathogenic	0.949
NPHS1	O60500-1.1	P519I	Pathogenic	0.968
NPHS1	O60500-1.1	P519K	Pathogenic	0.995
NPHS1	O60500-1.1	P519L	Pathogenic	0.963
NPHS1	O60500-1.1	P519M	Pathogenic	0.951
NPHS1	O60500-1.1	P519N	Pathogenic	0.971
NPHS1	O60500-1.1	P519Q	Pathogenic	0.977
NPHS1	O60500-1.1	P519R	Pathogenic	0.995
NPHS1	O60500-1.1	P519S	Pathogenic	0.965
NPHS1	O60500-1.1	P519T	Pathogenic	0.928
NPHS1	O60500-1.1	P519V	Pathogenic	0.923
NPHS1	O60500-1.1	P519W	Pathogenic	0.99
NPHS1	O60500-1.1	P519Y	Pathogenic	0.928
NPHS1	O60500-1.1	S520A	Pathogenic	0.762
NPHS1	O60500-1.1	S520C	Pathogenic	0.822
NPHS1	O60500-1.1	S520D	Pathogenic	0.835
NPHS1	O60500-1.1	S520E	Pathogenic	0.864
NPHS1	O60500-1.1	S520F	Pathogenic	0.97
NPHS1	O60500-1.1	S520G	Pathogenic	0.68
NPHS1	O60500-1.1	S520H	Pathogenic	0.735
NPHS1	O60500-1.1	S520I	Pathogenic	0.963
NPHS1	O60500-1.1	S520K	Pathogenic	0.952
NPHS1	O60500-1.1	S520L	Pathogenic	0.957
NPHS1	O60500-1.1	S520M	Pathogenic	0.943
NPHS1	O60500-1.1	S520N	Pathogenic	0.869
NPHS1	O60500-1.1	S520P	Pathogenic	0.774
NPHS1	O60500-1.1	S520Q	Pathogenic	0.794
NPHS1	O60500-1.1	S520R	Pathogenic	0.949
NPHS1	O60500-1.1	S520T	Pathogenic	0.805
NPHS1	O60500-1.1	S520V	Pathogenic	0.873
NPHS1	O60500-1.1	S520W	Pathogenic	0.988
NPHS1	O60500-1.1	S520Y	Pathogenic	0.917
NPHS1	O60500-1.1	D521A	Pathogenic	0.996
NPHS1	O60500-1.1	D521C	Pathogenic	0.996
NPHS1	O60500-1.1	D521E	Pathogenic	0.996
NPHS1	O60500-1.1	D521F	Pathogenic	1.0
NPHS1	O60500-1.1	D521G	Pathogenic	0.997
NPHS1	O60500-1.1	D521H	Pathogenic	0.997
NPHS1	O60500-1.1	D521I	Pathogenic	0.999
NPHS1	O60500-1.1	D521K	Pathogenic	0.994
NPHS1	O60500-1.1	D521L	Pathogenic	0.999
NPHS1	O60500-1.1	D521M	Pathogenic	0.999
NPHS1	O60500-1.1	D521N	Pathogenic	0.992
NPHS1	O60500-1.1	D521P	Pathogenic	0.997
NPHS1	O60500-1.1	D521Q	Pathogenic	0.996
NPHS1	O60500-1.1	D521R	Pathogenic	0.993
NPHS1	O60500-1.1	D521S	Pathogenic	0.996
NPHS1	O60500-1.1	D521T	Pathogenic	0.995
NPHS1	O60500-1.1	D521V	Pathogenic	0.998
NPHS1	O60500-1.1	D521W	Pathogenic	1.0
NPHS1	O60500-1.1	D521Y	Pathogenic	0.999
NPHS1	O60500-1.1	N522A	Pathogenic	0.998
NPHS1	O60500-1.1	N522C	Pathogenic	0.998
NPHS1	O60500-1.1	N522D	Pathogenic	0.996
NPHS1	O60500-1.1	N522E	Pathogenic	0.994
NPHS1	O60500-1.1	N522F	Pathogenic	1.0
NPHS1	O60500-1.1	N522G	Pathogenic	0.999
NPHS1	O60500-1.1	N522H	Pathogenic	0.999
NPHS1	O60500-1.1	N522I	Pathogenic	1.0
NPHS1	O60500-1.1	N522K	Pathogenic	0.998
NPHS1	O60500-1.1	N522L	Pathogenic	1.0
NPHS1	O60500-1.1	N522M	Pathogenic	0.999
NPHS1	O60500-1.1	N522P	Pathogenic	0.998
NPHS1	O60500-1.1	N522Q	Pathogenic	0.997
NPHS1	O60500-1.1	N522R	Pathogenic	0.999
NPHS1	O60500-1.1	N522S	Pathogenic	0.999
NPHS1	O60500-1.1	N522T	Pathogenic	0.998
NPHS1	O60500-1.1	N522V	Pathogenic	0.998
NPHS1	O60500-1.1	N522W	Pathogenic	1.0
NPHS1	O60500-1.1	N522Y	Pathogenic	0.999
NPHS1	O60500-1.1	Q523A	Neutral	0.125
NPHS1	O60500-1.1	Q523C	Neutral	0.101
NPHS1	O60500-1.1	Q523D	Neutral	0.111
NPHS1	O60500-1.1	Q523E	Neutral	0.13
NPHS1	O60500-1.1	Q523F	Neutral	0.239
NPHS1	O60500-1.1	Q523G	Neutral	0.087
NPHS1	O60500-1.1	Q523H	Neutral	0.056
NPHS1	O60500-1.1	Q523I	Neutral	0.199
NPHS1	O60500-1.1	Q523K	Neutral	0.198
NPHS1	O60500-1.1	Q523L	Neutral	0.241
NPHS1	O60500-1.1	Q523M	Neutral	0.26
NPHS1	O60500-1.1	Q523N	Neutral	0.079
NPHS1	O60500-1.1	Q523P	Neutral	0.132
NPHS1	O60500-1.1	Q523R	Neutral	0.255
NPHS1	O60500-1.1	Q523S	Neutral	0.1
NPHS1	O60500-1.1	Q523T	Neutral	0.067
NPHS1	O60500-1.1	Q523V	Neutral	0.131
NPHS1	O60500-1.1	Q523W	Pathogenic	0.644
NPHS1	O60500-1.1	Q523Y	Neutral	0.19
NPHS1	O60500-1.1	A524C	Pathogenic	0.99
NPHS1	O60500-1.1	A524D	Pathogenic	0.989
NPHS1	O60500-1.1	A524E	Pathogenic	0.994
NPHS1	O60500-1.1	A524F	Pathogenic	0.998
NPHS1	O60500-1.1	A524G	Pathogenic	0.982
NPHS1	O60500-1.1	A524H	Pathogenic	0.978
NPHS1	O60500-1.1	A524I	Pathogenic	0.998
NPHS1	O60500-1.1	A524K	Pathogenic	0.998
NPHS1	O60500-1.1	A524L	Pathogenic	0.998
NPHS1	O60500-1.1	A524M	Pathogenic	0.996
NPHS1	O60500-1.1	A524N	Pathogenic	0.987
NPHS1	O60500-1.1	A524P	Pathogenic	0.98
NPHS1	O60500-1.1	A524Q	Pathogenic	0.99
NPHS1	O60500-1.1	A524R	Pathogenic	0.999
NPHS1	O60500-1.1	A524S	Pathogenic	0.985
NPHS1	O60500-1.1	A524T	Pathogenic	0.978
NPHS1	O60500-1.1	A524V	Pathogenic	0.995
NPHS1	O60500-1.1	A524W	Pathogenic	0.999
NPHS1	O60500-1.1	A524Y	Pathogenic	0.994
NPHS1	O60500-1.1	K525A	Pathogenic	0.904
NPHS1	O60500-1.1	K525C	Pathogenic	0.881
NPHS1	O60500-1.1	K525D	Pathogenic	0.518
NPHS1	O60500-1.1	K525E	Pathogenic	0.655
NPHS1	O60500-1.1	K525F	Pathogenic	0.885
NPHS1	O60500-1.1	K525G	Pathogenic	0.862
NPHS1	O60500-1.1	K525H	Pathogenic	0.685
NPHS1	O60500-1.1	K525I	Pathogenic	0.911
NPHS1	O60500-1.1	K525L	Pathogenic	0.929
NPHS1	O60500-1.1	K525M	Pathogenic	0.906
NPHS1	O60500-1.1	K525N	Pathogenic	0.647
NPHS1	O60500-1.1	K525P	Pathogenic	0.91
NPHS1	O60500-1.1	K525Q	Pathogenic	0.759
NPHS1	O60500-1.1	K525R	Pathogenic	0.558
NPHS1	O60500-1.1	K525S	Pathogenic	0.88
NPHS1	O60500-1.1	K525T	Pathogenic	0.825
NPHS1	O60500-1.1	K525V	Pathogenic	0.909
NPHS1	O60500-1.1	K525W	Pathogenic	0.967
NPHS1	O60500-1.1	K525Y	Pathogenic	0.794
NPHS1	O60500-1.1	F526A	Pathogenic	0.992
NPHS1	O60500-1.1	F526C	Pathogenic	0.965
NPHS1	O60500-1.1	F526D	Pathogenic	0.996
NPHS1	O60500-1.1	F526E	Pathogenic	0.992
NPHS1	O60500-1.1	F526G	Pathogenic	0.995
NPHS1	O60500-1.1	F526H	Pathogenic	0.986
NPHS1	O60500-1.1	F526I	Pathogenic	0.885
NPHS1	O60500-1.1	F526K	Pathogenic	0.991
NPHS1	O60500-1.1	F526L	Pathogenic	0.896
NPHS1	O60500-1.1	F526M	Pathogenic	0.945
NPHS1	O60500-1.1	F526N	Pathogenic	0.994
NPHS1	O60500-1.1	F526P	Pathogenic	0.944
NPHS1	O60500-1.1	F526Q	Pathogenic	0.983
NPHS1	O60500-1.1	F526R	Pathogenic	0.993
NPHS1	O60500-1.1	F526S	Pathogenic	0.994
NPHS1	O60500-1.1	F526T	Pathogenic	0.986
NPHS1	O60500-1.1	F526V	Pathogenic	0.949
NPHS1	O60500-1.1	F526W	Pathogenic	0.971
NPHS1	O60500-1.1	F526Y	Pathogenic	0.987
NPHS1	O60500-1.1	T527A	Neutral	0.089
NPHS1	O60500-1.1	T527C	Neutral	0.102
NPHS1	O60500-1.1	T527D	Neutral	0.136
NPHS1	O60500-1.1	T527E	Neutral	0.153
NPHS1	O60500-1.1	T527F	Neutral	0.367
NPHS1	O60500-1.1	T527G	Neutral	0.085
NPHS1	O60500-1.1	T527H	Neutral	0.046
NPHS1	O60500-1.1	T527I	Neutral	0.405
NPHS1	O60500-1.1	T527K	Neutral	0.361
NPHS1	O60500-1.1	T527L	Neutral	0.369
NPHS1	O60500-1.1	T527M	Neutral	0.225
NPHS1	O60500-1.1	T527N	Neutral	0.158
NPHS1	O60500-1.1	T527P	Neutral	0.065
NPHS1	O60500-1.1	T527Q	Neutral	0.098
NPHS1	O60500-1.1	T527R	Neutral	0.439
NPHS1	O60500-1.1	T527S	Neutral	0.153
NPHS1	O60500-1.1	T527V	Neutral	0.213
NPHS1	O60500-1.1	T527W	Pathogenic	0.69
NPHS1	O60500-1.1	T527Y	Neutral	0.163
NPHS1	O60500-1.1	C528A	Pathogenic	0.981
NPHS1	O60500-1.1	C528D	Pathogenic	0.982
NPHS1	O60500-1.1	C528E	Pathogenic	0.979
NPHS1	O60500-1.1	C528F	Pathogenic	0.983
NPHS1	O60500-1.1	C528G	Pathogenic	0.974
NPHS1	O60500-1.1	C528H	Pathogenic	0.964
NPHS1	O60500-1.1	C528I	Pathogenic	0.985
NPHS1	O60500-1.1	C528K	Pathogenic	0.995
NPHS1	O60500-1.1	C528L	Pathogenic	0.983
NPHS1	O60500-1.1	C528M	Pathogenic	0.966
NPHS1	O60500-1.1	C528N	Pathogenic	0.98
NPHS1	O60500-1.1	C528P	Pathogenic	0.854
NPHS1	O60500-1.1	C528Q	Pathogenic	0.977
NPHS1	O60500-1.1	C528R	Pathogenic	0.997
NPHS1	O60500-1.1	C528S	Pathogenic	0.98
NPHS1	O60500-1.1	C528T	Pathogenic	0.965
NPHS1	O60500-1.1	C528V	Pathogenic	0.947
NPHS1	O60500-1.1	C528W	Pathogenic	0.995
NPHS1	O60500-1.1	C528Y	Pathogenic	0.953
NPHS1	O60500-1.1	K529A	Pathogenic	0.973
NPHS1	O60500-1.1	K529C	Pathogenic	0.966
NPHS1	O60500-1.1	K529D	Pathogenic	0.806
NPHS1	O60500-1.1	K529E	Pathogenic	0.88
NPHS1	O60500-1.1	K529F	Pathogenic	0.967
NPHS1	O60500-1.1	K529G	Pathogenic	0.96
NPHS1	O60500-1.1	K529H	Pathogenic	0.893
NPHS1	O60500-1.1	K529I	Pathogenic	0.975
NPHS1	O60500-1.1	K529L	Pathogenic	0.981
NPHS1	O60500-1.1	K529M	Pathogenic	0.974
NPHS1	O60500-1.1	K529N	Pathogenic	0.876
NPHS1	O60500-1.1	K529P	Pathogenic	0.975
NPHS1	O60500-1.1	K529Q	Pathogenic	0.924
NPHS1	O60500-1.1	K529R	Pathogenic	0.83
NPHS1	O60500-1.1	K529S	Pathogenic	0.966
NPHS1	O60500-1.1	K529T	Pathogenic	0.948
NPHS1	O60500-1.1	K529V	Pathogenic	0.975
NPHS1	O60500-1.1	K529W	Pathogenic	0.991
NPHS1	O60500-1.1	K529Y	Pathogenic	0.937
NPHS1	O60500-1.1	A530C	Pathogenic	0.93
NPHS1	O60500-1.1	A530D	Pathogenic	0.924
NPHS1	O60500-1.1	A530E	Pathogenic	0.958
NPHS1	O60500-1.1	A530F	Pathogenic	0.984
NPHS1	O60500-1.1	A530G	Pathogenic	0.884
NPHS1	O60500-1.1	A530H	Pathogenic	0.857
NPHS1	O60500-1.1	A530I	Pathogenic	0.987
NPHS1	O60500-1.1	A530K	Pathogenic	0.986
NPHS1	O60500-1.1	A530L	Pathogenic	0.984
NPHS1	O60500-1.1	A530M	Pathogenic	0.969
NPHS1	O60500-1.1	A530N	Pathogenic	0.914
NPHS1	O60500-1.1	A530P	Pathogenic	0.868
NPHS1	O60500-1.1	A530Q	Pathogenic	0.932
NPHS1	O60500-1.1	A530R	Pathogenic	0.99
NPHS1	O60500-1.1	A530S	Pathogenic	0.899
NPHS1	O60500-1.1	A530T	Pathogenic	0.86
NPHS1	O60500-1.1	A530V	Pathogenic	0.967
NPHS1	O60500-1.1	A530W	Pathogenic	0.994
NPHS1	O60500-1.1	A530Y	Pathogenic	0.955
NPHS1	O60500-1.1	G531A	Neutral	0.114
NPHS1	O60500-1.1	G531C	Neutral	0.142
NPHS1	O60500-1.1	G531D	Neutral	0.232
NPHS1	O60500-1.1	G531E	Neutral	0.203
NPHS1	O60500-1.1	G531F	Pathogenic	0.636
NPHS1	O60500-1.1	G531H	Neutral	0.129
NPHS1	O60500-1.1	G531I	Neutral	0.481
NPHS1	O60500-1.1	G531K	Neutral	0.443
NPHS1	O60500-1.1	G531L	Neutral	0.443
NPHS1	O60500-1.1	G531M	Neutral	0.371
NPHS1	O60500-1.1	G531N	Neutral	0.283
NPHS1	O60500-1.1	G531P	Neutral	0.155
NPHS1	O60500-1.1	G531Q	Neutral	0.133
NPHS1	O60500-1.1	G531R	Pathogenic	0.525
NPHS1	O60500-1.1	G531S	Neutral	0.09
NPHS1	O60500-1.1	G531T	Neutral	0.09
NPHS1	O60500-1.1	G531V	Neutral	0.269
NPHS1	O60500-1.1	G531W	Pathogenic	0.91
NPHS1	O60500-1.1	G531Y	Neutral	0.37
NPHS1	O60500-1.1	Q532A	Neutral	0.383
NPHS1	O60500-1.1	Q532C	Neutral	0.327
NPHS1	O60500-1.1	Q532D	Neutral	0.352
NPHS1	O60500-1.1	Q532E	Neutral	0.393
NPHS1	O60500-1.1	Q532F	Pathogenic	0.578
NPHS1	O60500-1.1	Q532G	Neutral	0.292
NPHS1	O60500-1.1	Q532H	Neutral	0.205
NPHS1	O60500-1.1	Q532I	Pathogenic	0.519
NPHS1	O60500-1.1	Q532K	Pathogenic	0.517
NPHS1	O60500-1.1	Q532L	Pathogenic	0.58
NPHS1	O60500-1.1	Q532M	Pathogenic	0.604
NPHS1	O60500-1.1	Q532N	Neutral	0.273
NPHS1	O60500-1.1	Q532P	Neutral	0.399
NPHS1	O60500-1.1	Q532R	Pathogenic	0.598
NPHS1	O60500-1.1	Q532S	Neutral	0.325
NPHS1	O60500-1.1	Q532T	Neutral	0.237
NPHS1	O60500-1.1	Q532V	Neutral	0.396
NPHS1	O60500-1.1	Q532W	Pathogenic	0.887
NPHS1	O60500-1.1	Q532Y	Pathogenic	0.506
NPHS1	O60500-1.1	L533A	Pathogenic	0.958
NPHS1	O60500-1.1	L533C	Pathogenic	0.843
NPHS1	O60500-1.1	L533D	Pathogenic	0.951
NPHS1	O60500-1.1	L533E	Pathogenic	0.94
NPHS1	O60500-1.1	L533F	Pathogenic	0.624
NPHS1	O60500-1.1	L533G	Pathogenic	0.945
NPHS1	O60500-1.1	L533H	Pathogenic	0.801
NPHS1	O60500-1.1	L533I	Pathogenic	0.744
NPHS1	O60500-1.1	L533K	Pathogenic	0.973
NPHS1	O60500-1.1	L533M	Pathogenic	0.834
NPHS1	O60500-1.1	L533N	Pathogenic	0.953
NPHS1	O60500-1.1	L533P	Pathogenic	0.765
NPHS1	O60500-1.1	L533Q	Pathogenic	0.918
NPHS1	O60500-1.1	L533R	Pathogenic	0.98
NPHS1	O60500-1.1	L533S	Pathogenic	0.957
NPHS1	O60500-1.1	L533T	Pathogenic	0.931
NPHS1	O60500-1.1	L533V	Pathogenic	0.843
NPHS1	O60500-1.1	L533W	Pathogenic	0.742
NPHS1	O60500-1.1	L533Y	Pathogenic	0.772
NPHS1	O60500-1.1	S534A	Neutral	0.414
NPHS1	O60500-1.1	S534C	Pathogenic	0.505
NPHS1	O60500-1.1	S534D	Pathogenic	0.528
NPHS1	O60500-1.1	S534E	Pathogenic	0.585
NPHS1	O60500-1.1	S534F	Pathogenic	0.879
NPHS1	O60500-1.1	S534G	Neutral	0.319
NPHS1	O60500-1.1	S534H	Neutral	0.38
NPHS1	O60500-1.1	S534I	Pathogenic	0.851
NPHS1	O60500-1.1	S534K	Pathogenic	0.815
NPHS1	O60500-1.1	S534L	Pathogenic	0.83
NPHS1	O60500-1.1	S534M	Pathogenic	0.784
NPHS1	O60500-1.1	S534N	Pathogenic	0.594
NPHS1	O60500-1.1	S534P	Neutral	0.431
NPHS1	O60500-1.1	S534Q	Neutral	0.46
NPHS1	O60500-1.1	S534R	Pathogenic	0.804
NPHS1	O60500-1.1	S534T	Neutral	0.477
NPHS1	O60500-1.1	S534V	Pathogenic	0.604
NPHS1	O60500-1.1	S534W	Pathogenic	0.949
NPHS1	O60500-1.1	S534Y	Pathogenic	0.709
NPHS1	O60500-1.1	A535C	Pathogenic	0.943
NPHS1	O60500-1.1	A535D	Pathogenic	0.938
NPHS1	O60500-1.1	A535E	Pathogenic	0.966
NPHS1	O60500-1.1	A535F	Pathogenic	0.987
NPHS1	O60500-1.1	A535G	Pathogenic	0.905
NPHS1	O60500-1.1	A535H	Pathogenic	0.882
NPHS1	O60500-1.1	A535I	Pathogenic	0.989
NPHS1	O60500-1.1	A535K	Pathogenic	0.989
NPHS1	O60500-1.1	A535L	Pathogenic	0.987
NPHS1	O60500-1.1	A535M	Pathogenic	0.975
NPHS1	O60500-1.1	A535N	Pathogenic	0.93
NPHS1	O60500-1.1	A535P	Pathogenic	0.891
NPHS1	O60500-1.1	A535Q	Pathogenic	0.945
NPHS1	O60500-1.1	A535R	Pathogenic	0.992
NPHS1	O60500-1.1	A535S	Pathogenic	0.917
NPHS1	O60500-1.1	A535T	Pathogenic	0.884
NPHS1	O60500-1.1	A535V	Pathogenic	0.973
NPHS1	O60500-1.1	A535W	Pathogenic	0.995
NPHS1	O60500-1.1	A535Y	Pathogenic	0.963
NPHS1	O60500-1.1	S536A	Neutral	0.377
NPHS1	O60500-1.1	S536C	Neutral	0.467
NPHS1	O60500-1.1	S536D	Neutral	0.49
NPHS1	O60500-1.1	S536E	Pathogenic	0.547
NPHS1	O60500-1.1	S536F	Pathogenic	0.861
NPHS1	O60500-1.1	S536G	Neutral	0.287
NPHS1	O60500-1.1	S536H	Neutral	0.345
NPHS1	O60500-1.1	S536I	Pathogenic	0.83
NPHS1	O60500-1.1	S536K	Pathogenic	0.791
NPHS1	O60500-1.1	S536L	Pathogenic	0.808
NPHS1	O60500-1.1	S536M	Pathogenic	0.757
NPHS1	O60500-1.1	S536N	Pathogenic	0.557
NPHS1	O60500-1.1	S536P	Neutral	0.394
NPHS1	O60500-1.1	S536Q	Neutral	0.422
NPHS1	O60500-1.1	S536R	Pathogenic	0.779
NPHS1	O60500-1.1	S536T	Neutral	0.439
NPHS1	O60500-1.1	S536V	Pathogenic	0.566
NPHS1	O60500-1.1	S536W	Pathogenic	0.941
NPHS1	O60500-1.1	S536Y	Pathogenic	0.676
NPHS1	O60500-1.1	T537A	Pathogenic	0.768
NPHS1	O60500-1.1	T537C	Pathogenic	0.794
NPHS1	O60500-1.1	T537D	Pathogenic	0.843
NPHS1	O60500-1.1	T537E	Pathogenic	0.86
NPHS1	O60500-1.1	T537F	Pathogenic	0.952
NPHS1	O60500-1.1	T537G	Pathogenic	0.76
NPHS1	O60500-1.1	T537H	Pathogenic	0.618
NPHS1	O60500-1.1	T537I	Pathogenic	0.959
NPHS1	O60500-1.1	T537K	Pathogenic	0.95
NPHS1	O60500-1.1	T537L	Pathogenic	0.952
NPHS1	O60500-1.1	T537M	Pathogenic	0.908
NPHS1	O60500-1.1	T537N	Pathogenic	0.864
NPHS1	O60500-1.1	T537P	Pathogenic	0.703
NPHS1	O60500-1.1	T537Q	Pathogenic	0.788
NPHS1	O60500-1.1	T537R	Pathogenic	0.964
NPHS1	O60500-1.1	T537S	Pathogenic	0.86
NPHS1	O60500-1.1	T537V	Pathogenic	0.902
NPHS1	O60500-1.1	T537W	Pathogenic	0.987
NPHS1	O60500-1.1	T537Y	Pathogenic	0.868
NPHS1	O60500-1.1	Q538A	Neutral	0.184
NPHS1	O60500-1.1	Q538C	Neutral	0.15
NPHS1	O60500-1.1	Q538D	Neutral	0.165
NPHS1	O60500-1.1	Q538E	Neutral	0.191
NPHS1	O60500-1.1	Q538F	Neutral	0.333
NPHS1	O60500-1.1	Q538G	Neutral	0.131
NPHS1	O60500-1.1	Q538H	Neutral	0.086
NPHS1	O60500-1.1	Q538I	Neutral	0.282
NPHS1	O60500-1.1	Q538K	Neutral	0.281
NPHS1	O60500-1.1	Q538L	Neutral	0.335
NPHS1	O60500-1.1	Q538M	Neutral	0.357
NPHS1	O60500-1.1	Q538N	Neutral	0.12
NPHS1	O60500-1.1	Q538P	Neutral	0.195
NPHS1	O60500-1.1	Q538R	Neutral	0.351
NPHS1	O60500-1.1	Q538S	Neutral	0.149
NPHS1	O60500-1.1	Q538T	Neutral	0.102
NPHS1	O60500-1.1	Q538V	Neutral	0.193
NPHS1	O60500-1.1	Q538W	Pathogenic	0.741
NPHS1	O60500-1.1	Q538Y	Neutral	0.271
NPHS1	O60500-1.1	L539A	Pathogenic	0.98
NPHS1	O60500-1.1	L539C	Pathogenic	0.919
NPHS1	O60500-1.1	L539D	Pathogenic	0.976
NPHS1	O60500-1.1	L539E	Pathogenic	0.971
NPHS1	O60500-1.1	L539F	Pathogenic	0.777
NPHS1	O60500-1.1	L539G	Pathogenic	0.973
NPHS1	O60500-1.1	L539H	Pathogenic	0.894
NPHS1	O60500-1.1	L539I	Pathogenic	0.86
NPHS1	O60500-1.1	L539K	Pathogenic	0.987
NPHS1	O60500-1.1	L539M	Pathogenic	0.914
NPHS1	O60500-1.1	L539N	Pathogenic	0.977
NPHS1	O60500-1.1	L539P	Pathogenic	0.873
NPHS1	O60500-1.1	L539Q	Pathogenic	0.959
NPHS1	O60500-1.1	L539R	Pathogenic	0.991
NPHS1	O60500-1.1	L539S	Pathogenic	0.979
NPHS1	O60500-1.1	L539T	Pathogenic	0.966
NPHS1	O60500-1.1	L539V	Pathogenic	0.919
NPHS1	O60500-1.1	L539W	Pathogenic	0.858
NPHS1	O60500-1.1	L539Y	Pathogenic	0.877
NPHS1	O60500-1.1	A540C	Neutral	0.001
NPHS1	O60500-1.1	A540D	Neutral	0.001
NPHS1	O60500-1.1	A540E	Neutral	0.002
NPHS1	O60500-1.1	A540F	Neutral	0.005
NPHS1	O60500-1.1	A540G	Neutral	0.001
NPHS1	O60500-1.1	A540H	Neutral	0.001
NPHS1	O60500-1.1	A540I	Neutral	0.006
NPHS1	O60500-1.1	A540K	Neutral	0.006
NPHS1	O60500-1.1	A540L	Neutral	0.005
NPHS1	O60500-1.1	A540M	Neutral	0.003
NPHS1	O60500-1.1	A540N	Neutral	0.001
NPHS1	O60500-1.1	A540P	Neutral	0.001
NPHS1	O60500-1.1	A540Q	Neutral	0.001
NPHS1	O60500-1.1	A540R	Neutral	0.008
NPHS1	O60500-1.1	A540S	Neutral	0.001
NPHS1	O60500-1.1	A540T	Neutral	0.001
NPHS1	O60500-1.1	A540V	Neutral	0.002
NPHS1	O60500-1.1	A540W	Neutral	0.014
NPHS1	O60500-1.1	A540Y	Neutral	0.002
NPHS1	O60500-1.1	V541A	Pathogenic	0.98
NPHS1	O60500-1.1	V541C	Pathogenic	0.887
NPHS1	O60500-1.1	V541D	Pathogenic	0.977
NPHS1	O60500-1.1	V541E	Pathogenic	0.976
NPHS1	O60500-1.1	V541F	Pathogenic	0.944
NPHS1	O60500-1.1	V541G	Pathogenic	0.974
NPHS1	O60500-1.1	V541H	Pathogenic	0.916
NPHS1	O60500-1.1	V541I	Pathogenic	0.985
NPHS1	O60500-1.1	V541K	Pathogenic	0.992
NPHS1	O60500-1.1	V541L	Pathogenic	0.962
NPHS1	O60500-1.1	V541M	Pathogenic	0.926
NPHS1	O60500-1.1	V541N	Pathogenic	0.967
NPHS1	O60500-1.1	V541P	Pathogenic	0.877
NPHS1	O60500-1.1	V541Q	Pathogenic	0.961
NPHS1	O60500-1.1	V541R	Pathogenic	0.992
NPHS1	O60500-1.1	V541S	Pathogenic	0.97
NPHS1	O60500-1.1	V541T	Pathogenic	0.967
NPHS1	O60500-1.1	V541W	Pathogenic	0.967
NPHS1	O60500-1.1	V541Y	Pathogenic	0.924
NPHS1	O60500-1.1	Q542A	Pathogenic	0.988
NPHS1	O60500-1.1	Q542C	Pathogenic	0.985
NPHS1	O60500-1.1	Q542D	Pathogenic	0.987
NPHS1	O60500-1.1	Q542E	Pathogenic	0.989
NPHS1	O60500-1.1	Q542F	Pathogenic	0.995
NPHS1	O60500-1.1	Q542G	Pathogenic	0.983
NPHS1	O60500-1.1	Q542H	Pathogenic	0.972
NPHS1	O60500-1.1	Q542I	Pathogenic	0.993
NPHS1	O60500-1.1	Q542K	Pathogenic	0.993
NPHS1	O60500-1.1	Q542L	Pathogenic	0.995
NPHS1	O60500-1.1	Q542M	Pathogenic	0.995
NPHS1	O60500-1.1	Q542N	Pathogenic	0.981
NPHS1	O60500-1.1	Q542P	Pathogenic	0.989
NPHS1	O60500-1.1	Q542R	Pathogenic	0.995
NPHS1	O60500-1.1	Q542S	Pathogenic	0.985
NPHS1	O60500-1.1	Q542T	Pathogenic	0.977
NPHS1	O60500-1.1	Q542V	Pathogenic	0.989
NPHS1	O60500-1.1	Q542W	Pathogenic	0.999
NPHS1	O60500-1.1	Q542Y	Pathogenic	0.993
NPHS1	O60500-1.1	F543A	Pathogenic	0.998
NPHS1	O60500-1.1	F543C	Pathogenic	0.992
NPHS1	O60500-1.1	F543D	Pathogenic	0.999
NPHS1	O60500-1.1	F543E	Pathogenic	0.998
NPHS1	O60500-1.1	F543G	Pathogenic	0.999
NPHS1	O60500-1.1	F543H	Pathogenic	0.997
NPHS1	O60500-1.1	F543I	Pathogenic	0.97
NPHS1	O60500-1.1	F543K	Pathogenic	0.998
NPHS1	O60500-1.1	F543L	Pathogenic	0.973
NPHS1	O60500-1.1	F543M	Pathogenic	0.987
NPHS1	O60500-1.1	F543N	Pathogenic	0.998
NPHS1	O60500-1.1	F543P	Pathogenic	0.986
NPHS1	O60500-1.1	F543Q	Pathogenic	0.996
NPHS1	O60500-1.1	F543R	Pathogenic	0.998
NPHS1	O60500-1.1	F543S	Pathogenic	0.999
NPHS1	O60500-1.1	F543T	Pathogenic	0.997
NPHS1	O60500-1.1	F543V	Pathogenic	0.988
NPHS1	O60500-1.1	F543W	Pathogenic	0.993
NPHS1	O60500-1.1	F543Y	Pathogenic	0.997
NPHS1	O60500-1.1	P544A	Pathogenic	0.556
NPHS1	O60500-1.1	P544C	Neutral	0.224
NPHS1	O60500-1.1	P544D	Pathogenic	0.787
NPHS1	O60500-1.1	P544E	Pathogenic	0.823
NPHS1	O60500-1.1	P544F	Pathogenic	0.629
NPHS1	O60500-1.1	P544G	Pathogenic	0.675
NPHS1	O60500-1.1	P544H	Pathogenic	0.551
NPHS1	O60500-1.1	P544I	Pathogenic	0.666
NPHS1	O60500-1.1	P544K	Pathogenic	0.936
NPHS1	O60500-1.1	P544L	Pathogenic	0.631
NPHS1	O60500-1.1	P544M	Pathogenic	0.559
NPHS1	O60500-1.1	P544N	Pathogenic	0.685
NPHS1	O60500-1.1	P544Q	Pathogenic	0.738
NPHS1	O60500-1.1	P544R	Pathogenic	0.931
NPHS1	O60500-1.1	P544S	Pathogenic	0.645
NPHS1	O60500-1.1	P544T	Neutral	0.457
NPHS1	O60500-1.1	P544V	Neutral	0.442
NPHS1	O60500-1.1	P544W	Pathogenic	0.867
NPHS1	O60500-1.1	P544Y	Neutral	0.459
NPHS1	O60500-1.1	P545A	Pathogenic	0.854
NPHS1	O60500-1.1	P545C	Pathogenic	0.575
NPHS1	O60500-1.1	P545D	Pathogenic	0.945
NPHS1	O60500-1.1	P545E	Pathogenic	0.956
NPHS1	O60500-1.1	P545F	Pathogenic	0.888
NPHS1	O60500-1.1	P545G	Pathogenic	0.907
NPHS1	O60500-1.1	P545H	Pathogenic	0.852
NPHS1	O60500-1.1	P545I	Pathogenic	0.903
NPHS1	O60500-1.1	P545K	Pathogenic	0.986
NPHS1	O60500-1.1	P545L	Pathogenic	0.889
NPHS1	O60500-1.1	P545M	Pathogenic	0.856
NPHS1	O60500-1.1	P545N	Pathogenic	0.911
NPHS1	O60500-1.1	P545Q	Pathogenic	0.929
NPHS1	O60500-1.1	P545R	Pathogenic	0.984
NPHS1	O60500-1.1	P545S	Pathogenic	0.895
NPHS1	O60500-1.1	P545T	Pathogenic	0.798
NPHS1	O60500-1.1	P545V	Pathogenic	0.788
NPHS1	O60500-1.1	P545W	Pathogenic	0.968
NPHS1	O60500-1.1	P545Y	Pathogenic	0.799
NPHS1	O60500-1.1	T546A	Neutral	0.12
NPHS1	O60500-1.1	T546C	Neutral	0.137
NPHS1	O60500-1.1	T546D	Neutral	0.181
NPHS1	O60500-1.1	T546E	Neutral	0.202
NPHS1	O60500-1.1	T546F	Neutral	0.447
NPHS1	O60500-1.1	T546G	Neutral	0.115
NPHS1	O60500-1.1	T546H	Neutral	0.062
NPHS1	O60500-1.1	T546I	Neutral	0.487
NPHS1	O60500-1.1	T546K	Neutral	0.441
NPHS1	O60500-1.1	T546L	Neutral	0.449
NPHS1	O60500-1.1	T546M	Neutral	0.289
NPHS1	O60500-1.1	T546N	Neutral	0.208
NPHS1	O60500-1.1	T546P	Neutral	0.089
NPHS1	O60500-1.1	T546Q	Neutral	0.132
NPHS1	O60500-1.1	T546R	Pathogenic	0.523
NPHS1	O60500-1.1	T546S	Neutral	0.201
NPHS1	O60500-1.1	T546V	Neutral	0.274
NPHS1	O60500-1.1	T546W	Pathogenic	0.757
NPHS1	O60500-1.1	T546Y	Neutral	0.213
NPHS1	O60500-1.1	N547A	Neutral	0.013
NPHS1	O60500-1.1	N547C	Neutral	0.015
NPHS1	O60500-1.1	N547D	Neutral	0.008
NPHS1	O60500-1.1	N547E	Neutral	0.005
NPHS1	O60500-1.1	N547F	Neutral	0.09
NPHS1	O60500-1.1	N547G	Neutral	0.028
NPHS1	O60500-1.1	N547H	Neutral	0.027
NPHS1	O60500-1.1	N547I	Neutral	0.073
NPHS1	O60500-1.1	N547K	Neutral	0.016
NPHS1	O60500-1.1	N547L	Neutral	0.063
NPHS1	O60500-1.1	N547M	Neutral	0.047
NPHS1	O60500-1.1	N547P	Neutral	0.014
NPHS1	O60500-1.1	N547Q	Neutral	0.01
NPHS1	O60500-1.1	N547R	Neutral	0.023
NPHS1	O60500-1.1	N547S	Neutral	0.022
NPHS1	O60500-1.1	N547T	Neutral	0.014
NPHS1	O60500-1.1	N547V	Neutral	0.02
NPHS1	O60500-1.1	N547W	Neutral	0.204
NPHS1	O60500-1.1	N547Y	Neutral	0.047
NPHS1	O60500-1.1	V548A	Pathogenic	0.604
NPHS1	O60500-1.1	V548C	Neutral	0.193
NPHS1	O60500-1.1	V548D	Pathogenic	0.564
NPHS1	O60500-1.1	V548E	Pathogenic	0.556
NPHS1	O60500-1.1	V548F	Neutral	0.339
NPHS1	O60500-1.1	V548G	Pathogenic	0.532
NPHS1	O60500-1.1	V548H	Neutral	0.248
NPHS1	O60500-1.1	V548I	Pathogenic	0.666
NPHS1	O60500-1.1	V548K	Pathogenic	0.796
NPHS1	O60500-1.1	V548L	Neutral	0.435
NPHS1	O60500-1.1	V548M	Neutral	0.277
NPHS1	O60500-1.1	V548N	Neutral	0.472
NPHS1	O60500-1.1	V548P	Neutral	0.178
NPHS1	O60500-1.1	V548Q	Neutral	0.431
NPHS1	O60500-1.1	V548R	Pathogenic	0.785
NPHS1	O60500-1.1	V548S	Neutral	0.498
NPHS1	O60500-1.1	V548T	Neutral	0.471
NPHS1	O60500-1.1	V548W	Neutral	0.47
NPHS1	O60500-1.1	V548Y	Neutral	0.27
NPHS1	O60500-1.1	T549A	Neutral	0.192
NPHS1	O60500-1.1	T549C	Neutral	0.218
NPHS1	O60500-1.1	T549D	Neutral	0.279
NPHS1	O60500-1.1	T549E	Neutral	0.307
NPHS1	O60500-1.1	T549F	Pathogenic	0.586
NPHS1	O60500-1.1	T549G	Neutral	0.186
NPHS1	O60500-1.1	T549H	Neutral	0.104
NPHS1	O60500-1.1	T549I	Pathogenic	0.625
NPHS1	O60500-1.1	T549K	Pathogenic	0.58
NPHS1	O60500-1.1	T549L	Pathogenic	0.588
NPHS1	O60500-1.1	T549M	Neutral	0.416
NPHS1	O60500-1.1	T549N	Neutral	0.315
NPHS1	O60500-1.1	T549P	Neutral	0.146
NPHS1	O60500-1.1	T549Q	Neutral	0.211
NPHS1	O60500-1.1	T549R	Pathogenic	0.657
NPHS1	O60500-1.1	T549S	Neutral	0.307
NPHS1	O60500-1.1	T549V	Neutral	0.398
NPHS1	O60500-1.1	T549W	Pathogenic	0.845
NPHS1	O60500-1.1	T549Y	Neutral	0.322
NPHS1	O60500-1.1	I550A	Pathogenic	0.999
NPHS1	O60500-1.1	I550C	Pathogenic	0.998
NPHS1	O60500-1.1	I550D	Pathogenic	1.0
NPHS1	O60500-1.1	I550E	Pathogenic	0.999
NPHS1	O60500-1.1	I550F	Pathogenic	0.99
NPHS1	O60500-1.1	I550G	Pathogenic	0.999
NPHS1	O60500-1.1	I550H	Pathogenic	0.997
NPHS1	O60500-1.1	I550K	Pathogenic	0.999
NPHS1	O60500-1.1	I550L	Pathogenic	0.995
NPHS1	O60500-1.1	I550M	Pathogenic	0.996
NPHS1	O60500-1.1	I550N	Pathogenic	0.999
NPHS1	O60500-1.1	I550P	Pathogenic	0.996
NPHS1	O60500-1.1	I550Q	Pathogenic	0.998
NPHS1	O60500-1.1	I550R	Pathogenic	1.0
NPHS1	O60500-1.1	I550S	Pathogenic	0.999
NPHS1	O60500-1.1	I550T	Pathogenic	0.999
NPHS1	O60500-1.1	I550V	Pathogenic	0.999
NPHS1	O60500-1.1	I550W	Pathogenic	0.991
NPHS1	O60500-1.1	I550Y	Pathogenic	0.996
NPHS1	O60500-1.1	L551A	Neutral	0.291
NPHS1	O60500-1.1	L551C	Neutral	0.088
NPHS1	O60500-1.1	L551D	Neutral	0.259
NPHS1	O60500-1.1	L551E	Neutral	0.219
NPHS1	O60500-1.1	L551F	Neutral	0.029
NPHS1	O60500-1.1	L551G	Neutral	0.235
NPHS1	O60500-1.1	L551H	Neutral	0.067
NPHS1	O60500-1.1	L551I	Neutral	0.049
NPHS1	O60500-1.1	L551K	Neutral	0.391
NPHS1	O60500-1.1	L551M	Neutral	0.082
NPHS1	O60500-1.1	L551N	Neutral	0.265
NPHS1	O60500-1.1	L551P	Neutral	0.055
NPHS1	O60500-1.1	L551Q	Neutral	0.166
NPHS1	O60500-1.1	L551R	Neutral	0.471
NPHS1	O60500-1.1	L551S	Neutral	0.286
NPHS1	O60500-1.1	L551T	Neutral	0.194
NPHS1	O60500-1.1	L551V	Neutral	0.088
NPHS1	O60500-1.1	L551W	Neutral	0.049
NPHS1	O60500-1.1	L551Y	Neutral	0.057
NPHS1	O60500-1.1	A552C	Pathogenic	0.614
NPHS1	O60500-1.1	A552D	Pathogenic	0.594
NPHS1	O60500-1.1	A552E	Pathogenic	0.733
NPHS1	O60500-1.1	A552F	Pathogenic	0.883
NPHS1	O60500-1.1	A552G	Neutral	0.479
NPHS1	O60500-1.1	A552H	Neutral	0.42
NPHS1	O60500-1.1	A552I	Pathogenic	0.899
NPHS1	O60500-1.1	A552K	Pathogenic	0.896
NPHS1	O60500-1.1	A552L	Pathogenic	0.884
NPHS1	O60500-1.1	A552M	Pathogenic	0.791
NPHS1	O60500-1.1	A552N	Pathogenic	0.562
NPHS1	O60500-1.1	A552P	Neutral	0.441
NPHS1	O60500-1.1	A552Q	Pathogenic	0.624
NPHS1	O60500-1.1	A552R	Pathogenic	0.923
NPHS1	O60500-1.1	A552S	Pathogenic	0.516
NPHS1	O60500-1.1	A552T	Neutral	0.426
NPHS1	O60500-1.1	A552V	Pathogenic	0.779
NPHS1	O60500-1.1	A552W	Pathogenic	0.951
NPHS1	O60500-1.1	A552Y	Pathogenic	0.717
NPHS1	O60500-1.1	N553A	Neutral	0.009
NPHS1	O60500-1.1	N553C	Neutral	0.011
NPHS1	O60500-1.1	N553D	Neutral	0.006
NPHS1	O60500-1.1	N553E	Neutral	0.004
NPHS1	O60500-1.1	N553F	Neutral	0.067
NPHS1	O60500-1.1	N553G	Neutral	0.02
NPHS1	O60500-1.1	N553H	Neutral	0.02
NPHS1	O60500-1.1	N553I	Neutral	0.054
NPHS1	O60500-1.1	N553K	Neutral	0.012
NPHS1	O60500-1.1	N553L	Neutral	0.046
NPHS1	O60500-1.1	N553M	Neutral	0.035
NPHS1	O60500-1.1	N553P	Neutral	0.01
NPHS1	O60500-1.1	N553Q	Neutral	0.007
NPHS1	O60500-1.1	N553R	Neutral	0.017
NPHS1	O60500-1.1	N553S	Neutral	0.016
NPHS1	O60500-1.1	N553T	Neutral	0.01
NPHS1	O60500-1.1	N553V	Neutral	0.015
NPHS1	O60500-1.1	N553W	Neutral	0.157
NPHS1	O60500-1.1	N553Y	Neutral	0.035
NPHS1	O60500-1.1	A554C	Neutral	0.025
NPHS1	O60500-1.1	A554D	Neutral	0.023
NPHS1	O60500-1.1	A554E	Neutral	0.043
NPHS1	O60500-1.1	A554F	Neutral	0.109
NPHS1	O60500-1.1	A554G	Neutral	0.015
NPHS1	O60500-1.1	A554H	Neutral	0.012
NPHS1	O60500-1.1	A554I	Neutral	0.126
NPHS1	O60500-1.1	A554K	Neutral	0.122
NPHS1	O60500-1.1	A554L	Neutral	0.11
NPHS1	O60500-1.1	A554M	Neutral	0.058
NPHS1	O60500-1.1	A554N	Neutral	0.02
NPHS1	O60500-1.1	A554P	Neutral	0.013
NPHS1	O60500-1.1	A554Q	Neutral	0.026
NPHS1	O60500-1.1	A554R	Neutral	0.162
NPHS1	O60500-1.1	A554S	Neutral	0.017
NPHS1	O60500-1.1	A554T	Neutral	0.012
NPHS1	O60500-1.1	A554V	Neutral	0.054
NPHS1	O60500-1.1	A554W	Neutral	0.24
NPHS1	O60500-1.1	A554Y	Neutral	0.039
NPHS1	O60500-1.1	S555A	Neutral	0.13
NPHS1	O60500-1.1	S555C	Neutral	0.178
NPHS1	O60500-1.1	S555D	Neutral	0.191
NPHS1	O60500-1.1	S555E	Neutral	0.229
NPHS1	O60500-1.1	S555F	Pathogenic	0.605
NPHS1	O60500-1.1	S555G	Neutral	0.09
NPHS1	O60500-1.1	S555H	Neutral	0.115
NPHS1	O60500-1.1	S555I	Pathogenic	0.547
NPHS1	O60500-1.1	S555K	Neutral	0.482
NPHS1	O60500-1.1	S555L	Pathogenic	0.509
NPHS1	O60500-1.1	S555M	Neutral	0.434
NPHS1	O60500-1.1	S555N	Neutral	0.236
NPHS1	O60500-1.1	S555P	Neutral	0.138
NPHS1	O60500-1.1	S555Q	Neutral	0.152
NPHS1	O60500-1.1	S555R	Neutral	0.464
NPHS1	O60500-1.1	S555T	Neutral	0.161
NPHS1	O60500-1.1	S555V	Neutral	0.243
NPHS1	O60500-1.1	S555W	Pathogenic	0.798
NPHS1	O60500-1.1	S555Y	Neutral	0.339
NPHS1	O60500-1.1	A556C	Neutral	0.141
NPHS1	O60500-1.1	A556D	Neutral	0.132
NPHS1	O60500-1.1	A556E	Neutral	0.221
NPHS1	O60500-1.1	A556F	Neutral	0.438
NPHS1	O60500-1.1	A556G	Neutral	0.087
NPHS1	O60500-1.1	A556H	Neutral	0.07
NPHS1	O60500-1.1	A556I	Neutral	0.479
NPHS1	O60500-1.1	A556K	Neutral	0.47
NPHS1	O60500-1.1	A556L	Neutral	0.441
NPHS1	O60500-1.1	A556M	Neutral	0.282
NPHS1	O60500-1.1	A556N	Neutral	0.117
NPHS1	O60500-1.1	A556P	Neutral	0.076
NPHS1	O60500-1.1	A556Q	Neutral	0.146
NPHS1	O60500-1.1	A556R	Pathogenic	0.552
NPHS1	O60500-1.1	A556S	Neutral	0.099
NPHS1	O60500-1.1	A556T	Neutral	0.071
NPHS1	O60500-1.1	A556V	Neutral	0.267
NPHS1	O60500-1.1	A556W	Pathogenic	0.669
NPHS1	O60500-1.1	A556Y	Neutral	0.208
NPHS1	O60500-1.1	L557A	Pathogenic	0.732
NPHS1	O60500-1.1	L557C	Neutral	0.39
NPHS1	O60500-1.1	L557D	Pathogenic	0.699
NPHS1	O60500-1.1	L557E	Pathogenic	0.65
NPHS1	O60500-1.1	L557F	Neutral	0.165
NPHS1	O60500-1.1	L557G	Pathogenic	0.671
NPHS1	O60500-1.1	L557H	Neutral	0.324
NPHS1	O60500-1.1	L557I	Neutral	0.257
NPHS1	O60500-1.1	L557K	Pathogenic	0.81
NPHS1	O60500-1.1	L557M	Neutral	0.373
NPHS1	O60500-1.1	L557N	Pathogenic	0.705
NPHS1	O60500-1.1	L557P	Neutral	0.279
NPHS1	O60500-1.1	L557Q	Pathogenic	0.57
NPHS1	O60500-1.1	L557R	Pathogenic	0.856
NPHS1	O60500-1.1	L557S	Pathogenic	0.726
NPHS1	O60500-1.1	L557T	Pathogenic	0.615
NPHS1	O60500-1.1	L557V	Neutral	0.39
NPHS1	O60500-1.1	L557W	Neutral	0.255
NPHS1	O60500-1.1	L557Y	Neutral	0.287
NPHS1	O60500-1.1	R558A	Pathogenic	0.98
NPHS1	O60500-1.1	R558C	Pathogenic	0.975
NPHS1	O60500-1.1	R558D	Pathogenic	0.792
NPHS1	O60500-1.1	R558E	Pathogenic	0.871
NPHS1	O60500-1.1	R558F	Pathogenic	0.976
NPHS1	O60500-1.1	R558G	Pathogenic	0.971
NPHS1	O60500-1.1	R558H	Pathogenic	0.945
NPHS1	O60500-1.1	R558I	Pathogenic	0.982
NPHS1	O60500-1.1	R558K	Pathogenic	0.828
NPHS1	O60500-1.1	R558L	Pathogenic	0.986
NPHS1	O60500-1.1	R558M	Pathogenic	0.981
NPHS1	O60500-1.1	R558N	Pathogenic	0.906
NPHS1	O60500-1.1	R558P	Pathogenic	0.973
NPHS1	O60500-1.1	R558Q	Pathogenic	0.943
NPHS1	O60500-1.1	R558S	Pathogenic	0.963
NPHS1	O60500-1.1	R558T	Pathogenic	0.961
NPHS1	O60500-1.1	R558V	Pathogenic	0.972
NPHS1	O60500-1.1	R558W	Pathogenic	0.988
NPHS1	O60500-1.1	R558Y	Pathogenic	0.939
NPHS1	O60500-1.1	P559A	Neutral	0.331
NPHS1	O60500-1.1	P559C	Neutral	0.102
NPHS1	O60500-1.1	P559D	Pathogenic	0.594
NPHS1	O60500-1.1	P559E	Pathogenic	0.647
NPHS1	O60500-1.1	P559F	Neutral	0.401
NPHS1	O60500-1.1	P559G	Neutral	0.451
NPHS1	O60500-1.1	P559H	Neutral	0.326
NPHS1	O60500-1.1	P559I	Neutral	0.44
NPHS1	O60500-1.1	P559K	Pathogenic	0.851
NPHS1	O60500-1.1	P559L	Neutral	0.403
NPHS1	O60500-1.1	P559M	Neutral	0.334
NPHS1	O60500-1.1	P559N	Neutral	0.462
NPHS1	O60500-1.1	P559Q	Pathogenic	0.526
NPHS1	O60500-1.1	P559R	Pathogenic	0.842
NPHS1	O60500-1.1	P559S	Neutral	0.417
NPHS1	O60500-1.1	P559T	Neutral	0.249
NPHS1	O60500-1.1	P559V	Neutral	0.238
NPHS1	O60500-1.1	P559W	Pathogenic	0.72
NPHS1	O60500-1.1	P559Y	Neutral	0.251
NPHS1	O60500-1.1	G560A	Pathogenic	0.977
NPHS1	O60500-1.1	G560C	Pathogenic	0.982
NPHS1	O60500-1.1	G560D	Pathogenic	0.99
NPHS1	O60500-1.1	G560E	Pathogenic	0.988
NPHS1	O60500-1.1	G560F	Pathogenic	0.998
NPHS1	O60500-1.1	G560H	Pathogenic	0.98
NPHS1	O60500-1.1	G560I	Pathogenic	0.997
NPHS1	O60500-1.1	G560K	Pathogenic	0.996
NPHS1	O60500-1.1	G560L	Pathogenic	0.996
NPHS1	O60500-1.1	G560M	Pathogenic	0.995
NPHS1	O60500-1.1	G560N	Pathogenic	0.992
NPHS1	O60500-1.1	G560P	Pathogenic	0.984
NPHS1	O60500-1.1	G560Q	Pathogenic	0.98
NPHS1	O60500-1.1	G560R	Pathogenic	0.997
NPHS1	O60500-1.1	G560S	Pathogenic	0.97
NPHS1	O60500-1.1	G560T	Pathogenic	0.97
NPHS1	O60500-1.1	G560V	Pathogenic	0.992
NPHS1	O60500-1.1	G560W	Pathogenic	1.0
NPHS1	O60500-1.1	G560Y	Pathogenic	0.995
NPHS1	O60500-1.1	D561A	Pathogenic	0.611
NPHS1	O60500-1.1	D561C	Pathogenic	0.647
NPHS1	O60500-1.1	D561E	Pathogenic	0.622
NPHS1	O60500-1.1	D561F	Pathogenic	0.939
NPHS1	O60500-1.1	D561G	Pathogenic	0.699
NPHS1	O60500-1.1	D561H	Pathogenic	0.659
NPHS1	O60500-1.1	D561I	Pathogenic	0.923
NPHS1	O60500-1.1	D561K	Pathogenic	0.512
NPHS1	O60500-1.1	D561L	Pathogenic	0.874
NPHS1	O60500-1.1	D561M	Pathogenic	0.837
NPHS1	O60500-1.1	D561N	Neutral	0.462
NPHS1	O60500-1.1	D561P	Pathogenic	0.715
NPHS1	O60500-1.1	D561Q	Pathogenic	0.608
NPHS1	O60500-1.1	D561R	Neutral	0.494
NPHS1	O60500-1.1	D561S	Pathogenic	0.645
NPHS1	O60500-1.1	D561T	Pathogenic	0.563
NPHS1	O60500-1.1	D561V	Pathogenic	0.763
NPHS1	O60500-1.1	D561W	Pathogenic	0.975
NPHS1	O60500-1.1	D561Y	Pathogenic	0.837
NPHS1	O60500-1.1	A562C	Neutral	0.092
NPHS1	O60500-1.1	A562D	Neutral	0.086
NPHS1	O60500-1.1	A562E	Neutral	0.15
NPHS1	O60500-1.1	A562F	Neutral	0.326
NPHS1	O60500-1.1	A562G	Neutral	0.056
NPHS1	O60500-1.1	A562H	Neutral	0.044
NPHS1	O60500-1.1	A562I	Neutral	0.363
NPHS1	O60500-1.1	A562K	Neutral	0.355
NPHS1	O60500-1.1	A562L	Neutral	0.328
NPHS1	O60500-1.1	A562M	Neutral	0.195
NPHS1	O60500-1.1	A562N	Neutral	0.076
NPHS1	O60500-1.1	A562P	Neutral	0.048
NPHS1	O60500-1.1	A562Q	Neutral	0.096
NPHS1	O60500-1.1	A562R	Neutral	0.433
NPHS1	O60500-1.1	A562S	Neutral	0.064
NPHS1	O60500-1.1	A562T	Neutral	0.045
NPHS1	O60500-1.1	A562V	Neutral	0.185
NPHS1	O60500-1.1	A562W	Pathogenic	0.556
NPHS1	O60500-1.1	A562Y	Neutral	0.14
NPHS1	O60500-1.1	L563A	Pathogenic	0.886
NPHS1	O60500-1.1	L563C	Pathogenic	0.645
NPHS1	O60500-1.1	L563D	Pathogenic	0.869
NPHS1	O60500-1.1	L563E	Pathogenic	0.841
NPHS1	O60500-1.1	L563F	Neutral	0.359
NPHS1	O60500-1.1	L563G	Pathogenic	0.853
NPHS1	O60500-1.1	L563H	Pathogenic	0.576
NPHS1	O60500-1.1	L563I	Neutral	0.496
NPHS1	O60500-1.1	L563K	Pathogenic	0.924
NPHS1	O60500-1.1	L563M	Pathogenic	0.629
NPHS1	O60500-1.1	L563N	Pathogenic	0.872
NPHS1	O60500-1.1	L563P	Pathogenic	0.524
NPHS1	O60500-1.1	L563Q	Pathogenic	0.79
NPHS1	O60500-1.1	L563R	Pathogenic	0.944
NPHS1	O60500-1.1	L563S	Pathogenic	0.883
NPHS1	O60500-1.1	L563T	Pathogenic	0.819
NPHS1	O60500-1.1	L563V	Pathogenic	0.645
NPHS1	O60500-1.1	L563W	Neutral	0.493
NPHS1	O60500-1.1	L563Y	Pathogenic	0.534
NPHS1	O60500-1.1	N564A	Neutral	0.05
NPHS1	O60500-1.1	N564C	Neutral	0.058
NPHS1	O60500-1.1	N564D	Neutral	0.032
NPHS1	O60500-1.1	N564E	Neutral	0.022
NPHS1	O60500-1.1	N564F	Neutral	0.29
NPHS1	O60500-1.1	N564G	Neutral	0.105
NPHS1	O60500-1.1	N564H	Neutral	0.103
NPHS1	O60500-1.1	N564I	Neutral	0.244
NPHS1	O60500-1.1	N564K	Neutral	0.065
NPHS1	O60500-1.1	N564L	Neutral	0.217
NPHS1	O60500-1.1	N564M	Neutral	0.17
NPHS1	O60500-1.1	N564P	Neutral	0.054
NPHS1	O60500-1.1	N564Q	Neutral	0.04
NPHS1	O60500-1.1	N564R	Neutral	0.087
NPHS1	O60500-1.1	N564S	Neutral	0.084
NPHS1	O60500-1.1	N564T	Neutral	0.056
NPHS1	O60500-1.1	N564V	Neutral	0.079
NPHS1	O60500-1.1	N564W	Pathogenic	0.514
NPHS1	O60500-1.1	N564Y	Neutral	0.17
NPHS1	O60500-1.1	L565A	Pathogenic	0.995
NPHS1	O60500-1.1	L565C	Pathogenic	0.979
NPHS1	O60500-1.1	L565D	Pathogenic	0.994
NPHS1	O60500-1.1	L565E	Pathogenic	0.993
NPHS1	O60500-1.1	L565F	Pathogenic	0.936
NPHS1	O60500-1.1	L565G	Pathogenic	0.993
NPHS1	O60500-1.1	L565H	Pathogenic	0.973
NPHS1	O60500-1.1	L565I	Pathogenic	0.963
NPHS1	O60500-1.1	L565K	Pathogenic	0.997
NPHS1	O60500-1.1	L565M	Pathogenic	0.978
NPHS1	O60500-1.1	L565N	Pathogenic	0.994
NPHS1	O60500-1.1	L565P	Pathogenic	0.966
NPHS1	O60500-1.1	L565Q	Pathogenic	0.99
NPHS1	O60500-1.1	L565R	Pathogenic	0.998
NPHS1	O60500-1.1	L565S	Pathogenic	0.995
NPHS1	O60500-1.1	L565T	Pathogenic	0.992
NPHS1	O60500-1.1	L565V	Pathogenic	0.979
NPHS1	O60500-1.1	L565W	Pathogenic	0.962
NPHS1	O60500-1.1	L565Y	Pathogenic	0.968
NPHS1	O60500-1.1	T566A	Pathogenic	0.645
NPHS1	O60500-1.1	T566C	Pathogenic	0.68
NPHS1	O60500-1.1	T566D	Pathogenic	0.747
NPHS1	O60500-1.1	T566E	Pathogenic	0.772
NPHS1	O60500-1.1	T566F	Pathogenic	0.915
NPHS1	O60500-1.1	T566G	Pathogenic	0.635
NPHS1	O60500-1.1	T566H	Neutral	0.471
NPHS1	O60500-1.1	T566I	Pathogenic	0.927
NPHS1	O60500-1.1	T566K	Pathogenic	0.913
NPHS1	O60500-1.1	T566L	Pathogenic	0.916
NPHS1	O60500-1.1	T566M	Pathogenic	0.845
NPHS1	O60500-1.1	T566N	Pathogenic	0.778
NPHS1	O60500-1.1	T566P	Pathogenic	0.566
NPHS1	O60500-1.1	T566Q	Pathogenic	0.671
NPHS1	O60500-1.1	T566R	Pathogenic	0.936
NPHS1	O60500-1.1	T566S	Pathogenic	0.772
NPHS1	O60500-1.1	T566V	Pathogenic	0.835
NPHS1	O60500-1.1	T566W	Pathogenic	0.977
NPHS1	O60500-1.1	T566Y	Pathogenic	0.784
NPHS1	O60500-1.1	C567A	Pathogenic	0.977
NPHS1	O60500-1.1	C567D	Pathogenic	0.979
NPHS1	O60500-1.1	C567E	Pathogenic	0.975
NPHS1	O60500-1.1	C567F	Pathogenic	0.98
NPHS1	O60500-1.1	C567G	Pathogenic	0.97
NPHS1	O60500-1.1	C567H	Pathogenic	0.958
NPHS1	O60500-1.1	C567I	Pathogenic	0.983
NPHS1	O60500-1.1	C567K	Pathogenic	0.995
NPHS1	O60500-1.1	C567L	Pathogenic	0.98
NPHS1	O60500-1.1	C567M	Pathogenic	0.96
NPHS1	O60500-1.1	C567N	Pathogenic	0.976
NPHS1	O60500-1.1	C567P	Pathogenic	0.832
NPHS1	O60500-1.1	C567Q	Pathogenic	0.972
NPHS1	O60500-1.1	C567R	Pathogenic	0.996
NPHS1	O60500-1.1	C567S	Pathogenic	0.977
NPHS1	O60500-1.1	C567T	Pathogenic	0.959
NPHS1	O60500-1.1	C567V	Pathogenic	0.937
NPHS1	O60500-1.1	C567W	Pathogenic	0.995
NPHS1	O60500-1.1	C567Y	Pathogenic	0.945
NPHS1	O60500-1.1	V568A	Neutral	0.166
NPHS1	O60500-1.1	V568C	Neutral	0.03
NPHS1	O60500-1.1	V568D	Neutral	0.145
NPHS1	O60500-1.1	V568E	Neutral	0.141
NPHS1	O60500-1.1	V568F	Neutral	0.063
NPHS1	O60500-1.1	V568G	Neutral	0.129
NPHS1	O60500-1.1	V568H	Neutral	0.041
NPHS1	O60500-1.1	V568I	Neutral	0.207
NPHS1	O60500-1.1	V568K	Neutral	0.338
NPHS1	O60500-1.1	V568L	Neutral	0.091
NPHS1	O60500-1.1	V568M	Neutral	0.048
NPHS1	O60500-1.1	V568N	Neutral	0.105
NPHS1	O60500-1.1	V568P	Neutral	0.027
NPHS1	O60500-1.1	V568Q	Neutral	0.09
NPHS1	O60500-1.1	V568R	Neutral	0.323
NPHS1	O60500-1.1	V568S	Neutral	0.115
NPHS1	O60500-1.1	V568T	Neutral	0.104
NPHS1	O60500-1.1	V568W	Neutral	0.104
NPHS1	O60500-1.1	V568Y	Neutral	0.046
NPHS1	O60500-1.1	S569A	Pathogenic	0.597
NPHS1	O60500-1.1	S569C	Pathogenic	0.682
NPHS1	O60500-1.1	S569D	Pathogenic	0.702
NPHS1	O60500-1.1	S569E	Pathogenic	0.747
NPHS1	O60500-1.1	S569F	Pathogenic	0.938
NPHS1	O60500-1.1	S569G	Neutral	0.496
NPHS1	O60500-1.1	S569H	Pathogenic	0.563
NPHS1	O60500-1.1	S569I	Pathogenic	0.923
NPHS1	O60500-1.1	S569K	Pathogenic	0.902
NPHS1	O60500-1.1	S569L	Pathogenic	0.911
NPHS1	O60500-1.1	S569M	Pathogenic	0.884
NPHS1	O60500-1.1	S569N	Pathogenic	0.755
NPHS1	O60500-1.1	S569P	Pathogenic	0.614
NPHS1	O60500-1.1	S569Q	Pathogenic	0.641
NPHS1	O60500-1.1	S569R	Pathogenic	0.896
NPHS1	O60500-1.1	S569T	Pathogenic	0.657
NPHS1	O60500-1.1	S569V	Pathogenic	0.762
NPHS1	O60500-1.1	S569W	Pathogenic	0.975
NPHS1	O60500-1.1	S569Y	Pathogenic	0.836
NPHS1	O60500-1.1	V570A	Neutral	0.298
NPHS1	O60500-1.1	V570C	Neutral	0.062
NPHS1	O60500-1.1	V570D	Neutral	0.265
NPHS1	O60500-1.1	V570E	Neutral	0.259
NPHS1	O60500-1.1	V570F	Neutral	0.125
NPHS1	O60500-1.1	V570G	Neutral	0.241
NPHS1	O60500-1.1	V570H	Neutral	0.084
NPHS1	O60500-1.1	V570I	Neutral	0.357
NPHS1	O60500-1.1	V570K	Pathogenic	0.521
NPHS1	O60500-1.1	V570L	Neutral	0.177
NPHS1	O60500-1.1	V570M	Neutral	0.096
NPHS1	O60500-1.1	V570N	Neutral	0.2
NPHS1	O60500-1.1	V570P	Neutral	0.057
NPHS1	O60500-1.1	V570Q	Neutral	0.174
NPHS1	O60500-1.1	V570R	Pathogenic	0.504
NPHS1	O60500-1.1	V570S	Neutral	0.217
NPHS1	O60500-1.1	V570T	Neutral	0.198
NPHS1	O60500-1.1	V570W	Neutral	0.198
NPHS1	O60500-1.1	V570Y	Neutral	0.093
NPHS1	O60500-1.1	S571A	Pathogenic	0.959
NPHS1	O60500-1.1	S571C	Pathogenic	0.972
NPHS1	O60500-1.1	S571D	Pathogenic	0.974
NPHS1	O60500-1.1	S571E	Pathogenic	0.979
NPHS1	O60500-1.1	S571F	Pathogenic	0.996
NPHS1	O60500-1.1	S571G	Pathogenic	0.94
NPHS1	O60500-1.1	S571H	Pathogenic	0.954
NPHS1	O60500-1.1	S571I	Pathogenic	0.995
NPHS1	O60500-1.1	S571K	Pathogenic	0.993
NPHS1	O60500-1.1	S571L	Pathogenic	0.994
NPHS1	O60500-1.1	S571M	Pathogenic	0.992
NPHS1	O60500-1.1	S571N	Pathogenic	0.98
NPHS1	O60500-1.1	S571P	Pathogenic	0.962
NPHS1	O60500-1.1	S571Q	Pathogenic	0.966
NPHS1	O60500-1.1	S571R	Pathogenic	0.993
NPHS1	O60500-1.1	S571T	Pathogenic	0.968
NPHS1	O60500-1.1	S571V	Pathogenic	0.981
NPHS1	O60500-1.1	S571W	Pathogenic	0.998
NPHS1	O60500-1.1	S571Y	Pathogenic	0.988
NPHS1	O60500-1.1	S572A	Pathogenic	0.958
NPHS1	O60500-1.1	S572C	Pathogenic	0.971
NPHS1	O60500-1.1	S572D	Pathogenic	0.973
NPHS1	O60500-1.1	S572E	Pathogenic	0.979
NPHS1	O60500-1.1	S572F	Pathogenic	0.996
NPHS1	O60500-1.1	S572G	Pathogenic	0.938
NPHS1	O60500-1.1	S572H	Pathogenic	0.952
NPHS1	O60500-1.1	S572I	Pathogenic	0.995
NPHS1	O60500-1.1	S572K	Pathogenic	0.993
NPHS1	O60500-1.1	S572L	Pathogenic	0.994
NPHS1	O60500-1.1	S572M	Pathogenic	0.992
NPHS1	O60500-1.1	S572N	Pathogenic	0.979
NPHS1	O60500-1.1	S572P	Pathogenic	0.961
NPHS1	O60500-1.1	S572Q	Pathogenic	0.965
NPHS1	O60500-1.1	S572R	Pathogenic	0.993
NPHS1	O60500-1.1	S572T	Pathogenic	0.967
NPHS1	O60500-1.1	S572V	Pathogenic	0.98
NPHS1	O60500-1.1	S572W	Pathogenic	0.998
NPHS1	O60500-1.1	S572Y	Pathogenic	0.987
NPHS1	O60500-1.1	N573A	Pathogenic	0.996
NPHS1	O60500-1.1	N573C	Pathogenic	0.997
NPHS1	O60500-1.1	N573D	Pathogenic	0.994
NPHS1	O60500-1.1	N573E	Pathogenic	0.991
NPHS1	O60500-1.1	N573F	Pathogenic	1.0
NPHS1	O60500-1.1	N573G	Pathogenic	0.998
NPHS1	O60500-1.1	N573H	Pathogenic	0.998
NPHS1	O60500-1.1	N573I	Pathogenic	0.999
NPHS1	O60500-1.1	N573K	Pathogenic	0.997
NPHS1	O60500-1.1	N573L	Pathogenic	0.999
NPHS1	O60500-1.1	N573M	Pathogenic	0.999
NPHS1	O60500-1.1	N573P	Pathogenic	0.997
NPHS1	O60500-1.1	N573Q	Pathogenic	0.995
NPHS1	O60500-1.1	N573R	Pathogenic	0.998
NPHS1	O60500-1.1	N573S	Pathogenic	0.998
NPHS1	O60500-1.1	N573T	Pathogenic	0.997
NPHS1	O60500-1.1	N573V	Pathogenic	0.998
NPHS1	O60500-1.1	N573W	Pathogenic	1.0
NPHS1	O60500-1.1	N573Y	Pathogenic	0.999
NPHS1	O60500-1.1	P574A	Pathogenic	0.97
NPHS1	O60500-1.1	P574C	Pathogenic	0.883
NPHS1	O60500-1.1	P574D	Pathogenic	0.99
NPHS1	O60500-1.1	P574E	Pathogenic	0.992
NPHS1	O60500-1.1	P574F	Pathogenic	0.978
NPHS1	O60500-1.1	P574G	Pathogenic	0.982
NPHS1	O60500-1.1	P574H	Pathogenic	0.97
NPHS1	O60500-1.1	P574I	Pathogenic	0.981
NPHS1	O60500-1.1	P574K	Pathogenic	0.997
NPHS1	O60500-1.1	P574L	Pathogenic	0.978
NPHS1	O60500-1.1	P574M	Pathogenic	0.971
NPHS1	O60500-1.1	P574N	Pathogenic	0.983
NPHS1	O60500-1.1	P574Q	Pathogenic	0.987
NPHS1	O60500-1.1	P574R	Pathogenic	0.997
NPHS1	O60500-1.1	P574S	Pathogenic	0.979
NPHS1	O60500-1.1	P574T	Pathogenic	0.957
NPHS1	O60500-1.1	P574V	Pathogenic	0.954
NPHS1	O60500-1.1	P574W	Pathogenic	0.994
NPHS1	O60500-1.1	P574Y	Pathogenic	0.957
NPHS1	O60500-1.1	P575A	Neutral	0.049
NPHS1	O60500-1.1	P575C	Neutral	0.012
NPHS1	O60500-1.1	P575D	Neutral	0.131
NPHS1	O60500-1.1	P575E	Neutral	0.16
NPHS1	O60500-1.1	P575F	Neutral	0.065
NPHS1	O60500-1.1	P575G	Neutral	0.078
NPHS1	O60500-1.1	P575H	Neutral	0.048
NPHS1	O60500-1.1	P575I	Neutral	0.075
NPHS1	O60500-1.1	P575K	Neutral	0.372
NPHS1	O60500-1.1	P575L	Neutral	0.065
NPHS1	O60500-1.1	P575M	Neutral	0.049
NPHS1	O60500-1.1	P575N	Neutral	0.081
NPHS1	O60500-1.1	P575Q	Neutral	0.103
NPHS1	O60500-1.1	P575R	Neutral	0.356
NPHS1	O60500-1.1	P575S	Neutral	0.069
NPHS1	O60500-1.1	P575T	Neutral	0.033
NPHS1	O60500-1.1	P575V	Neutral	0.031
NPHS1	O60500-1.1	P575W	Neutral	0.21
NPHS1	O60500-1.1	P575Y	Neutral	0.033
NPHS1	O60500-1.1	V576A	Pathogenic	0.59
NPHS1	O60500-1.1	V576C	Neutral	0.184
NPHS1	O60500-1.1	V576D	Pathogenic	0.551
NPHS1	O60500-1.1	V576E	Pathogenic	0.542
NPHS1	O60500-1.1	V576F	Neutral	0.326
NPHS1	O60500-1.1	V576G	Pathogenic	0.518
NPHS1	O60500-1.1	V576H	Neutral	0.238
NPHS1	O60500-1.1	V576I	Pathogenic	0.654
NPHS1	O60500-1.1	V576K	Pathogenic	0.787
NPHS1	O60500-1.1	V576L	Neutral	0.422
NPHS1	O60500-1.1	V576M	Neutral	0.266
NPHS1	O60500-1.1	V576N	Neutral	0.459
NPHS1	O60500-1.1	V576P	Neutral	0.17
NPHS1	O60500-1.1	V576Q	Neutral	0.417
NPHS1	O60500-1.1	V576R	Pathogenic	0.775
NPHS1	O60500-1.1	V576S	Neutral	0.484
NPHS1	O60500-1.1	V576T	Neutral	0.457
NPHS1	O60500-1.1	V576W	Neutral	0.456
NPHS1	O60500-1.1	V576Y	Neutral	0.259
NPHS1	O60500-1.1	N577A	Neutral	0.07
NPHS1	O60500-1.1	N577C	Neutral	0.081
NPHS1	O60500-1.1	N577D	Neutral	0.045
NPHS1	O60500-1.1	N577E	Neutral	0.031
NPHS1	O60500-1.1	N577F	Neutral	0.368
NPHS1	O60500-1.1	N577G	Neutral	0.143
NPHS1	O60500-1.1	N577H	Neutral	0.141
NPHS1	O60500-1.1	N577I	Neutral	0.315
NPHS1	O60500-1.1	N577K	Neutral	0.09
NPHS1	O60500-1.1	N577L	Neutral	0.283
NPHS1	O60500-1.1	N577M	Neutral	0.226
NPHS1	O60500-1.1	N577P	Neutral	0.075
NPHS1	O60500-1.1	N577Q	Neutral	0.056
NPHS1	O60500-1.1	N577R	Neutral	0.12
NPHS1	O60500-1.1	N577S	Neutral	0.116
NPHS1	O60500-1.1	N577T	Neutral	0.078
NPHS1	O60500-1.1	N577V	Neutral	0.109
NPHS1	O60500-1.1	N577W	Pathogenic	0.601
NPHS1	O60500-1.1	N577Y	Neutral	0.226
NPHS1	O60500-1.1	L578A	Pathogenic	0.915
NPHS1	O60500-1.1	L578C	Pathogenic	0.716
NPHS1	O60500-1.1	L578D	Pathogenic	0.901
NPHS1	O60500-1.1	L578E	Pathogenic	0.88
NPHS1	O60500-1.1	L578F	Neutral	0.437
NPHS1	O60500-1.1	L578G	Pathogenic	0.889
NPHS1	O60500-1.1	L578H	Pathogenic	0.653
NPHS1	O60500-1.1	L578I	Pathogenic	0.576
NPHS1	O60500-1.1	L578K	Pathogenic	0.944
NPHS1	O60500-1.1	L578M	Pathogenic	0.701
NPHS1	O60500-1.1	L578N	Pathogenic	0.904
NPHS1	O60500-1.1	L578P	Pathogenic	0.604
NPHS1	O60500-1.1	L578Q	Pathogenic	0.839
NPHS1	O60500-1.1	L578R	Pathogenic	0.959
NPHS1	O60500-1.1	L578S	Pathogenic	0.913
NPHS1	O60500-1.1	L578T	Pathogenic	0.863
NPHS1	O60500-1.1	L578V	Pathogenic	0.716
NPHS1	O60500-1.1	L578W	Pathogenic	0.574
NPHS1	O60500-1.1	L578Y	Pathogenic	0.613
NPHS1	O60500-1.1	S579A	Pathogenic	0.76
NPHS1	O60500-1.1	S579C	Pathogenic	0.821
NPHS1	O60500-1.1	S579D	Pathogenic	0.834
NPHS1	O60500-1.1	S579E	Pathogenic	0.864
NPHS1	O60500-1.1	S579F	Pathogenic	0.97
NPHS1	O60500-1.1	S579G	Pathogenic	0.678
NPHS1	O60500-1.1	S579H	Pathogenic	0.734
NPHS1	O60500-1.1	S579I	Pathogenic	0.962
NPHS1	O60500-1.1	S579K	Pathogenic	0.952
NPHS1	O60500-1.1	S579L	Pathogenic	0.957
NPHS1	O60500-1.1	S579M	Pathogenic	0.942
NPHS1	O60500-1.1	S579N	Pathogenic	0.868
NPHS1	O60500-1.1	S579P	Pathogenic	0.773
NPHS1	O60500-1.1	S579Q	Pathogenic	0.793
NPHS1	O60500-1.1	S579R	Pathogenic	0.948
NPHS1	O60500-1.1	S579T	Pathogenic	0.804
NPHS1	O60500-1.1	S579V	Pathogenic	0.872
NPHS1	O60500-1.1	S579W	Pathogenic	0.988
NPHS1	O60500-1.1	S579Y	Pathogenic	0.916
NPHS1	O60500-1.1	W580A	Pathogenic	1.0
NPHS1	O60500-1.1	W580C	Pathogenic	1.0
NPHS1	O60500-1.1	W580D	Pathogenic	1.0
NPHS1	O60500-1.1	W580E	Pathogenic	1.0
NPHS1	O60500-1.1	W580F	Pathogenic	0.999
NPHS1	O60500-1.1	W580G	Pathogenic	1.0
NPHS1	O60500-1.1	W580H	Pathogenic	1.0
NPHS1	O60500-1.1	W580I	Pathogenic	0.995
NPHS1	O60500-1.1	W580K	Pathogenic	1.0
NPHS1	O60500-1.1	W580L	Pathogenic	0.997
NPHS1	O60500-1.1	W580M	Pathogenic	0.999
NPHS1	O60500-1.1	W580N	Pathogenic	1.0
NPHS1	O60500-1.1	W580P	Pathogenic	0.999
NPHS1	O60500-1.1	W580Q	Pathogenic	1.0
NPHS1	O60500-1.1	W580R	Pathogenic	1.0
NPHS1	O60500-1.1	W580S	Pathogenic	1.0
NPHS1	O60500-1.1	W580T	Pathogenic	1.0
NPHS1	O60500-1.1	W580V	Pathogenic	0.999
NPHS1	O60500-1.1	W580Y	Pathogenic	1.0
NPHS1	O60500-1.1	D581A	Neutral	0.168
NPHS1	O60500-1.1	D581C	Neutral	0.191
NPHS1	O60500-1.1	D581E	Neutral	0.175
NPHS1	O60500-1.1	D581F	Pathogenic	0.663
NPHS1	O60500-1.1	D581G	Neutral	0.23
NPHS1	O60500-1.1	D581H	Neutral	0.199
NPHS1	O60500-1.1	D581I	Pathogenic	0.608
NPHS1	O60500-1.1	D581K	Neutral	0.119
NPHS1	O60500-1.1	D581L	Neutral	0.472
NPHS1	O60500-1.1	D581M	Neutral	0.398
NPHS1	O60500-1.1	D581N	Neutral	0.099
NPHS1	O60500-1.1	D581P	Neutral	0.244
NPHS1	O60500-1.1	D581Q	Neutral	0.167
NPHS1	O60500-1.1	D581R	Neutral	0.112
NPHS1	O60500-1.1	D581S	Neutral	0.189
NPHS1	O60500-1.1	D581T	Neutral	0.142
NPHS1	O60500-1.1	D581V	Neutral	0.292
NPHS1	O60500-1.1	D581W	Pathogenic	0.836
NPHS1	O60500-1.1	D581Y	Neutral	0.398
NPHS1	O60500-1.1	K582A	Pathogenic	0.992
NPHS1	O60500-1.1	K582C	Pathogenic	0.99
NPHS1	O60500-1.1	K582D	Pathogenic	0.938
NPHS1	O60500-1.1	K582E	Pathogenic	0.964
NPHS1	O60500-1.1	K582F	Pathogenic	0.991
NPHS1	O60500-1.1	K582G	Pathogenic	0.989
NPHS1	O60500-1.1	K582H	Pathogenic	0.968
NPHS1	O60500-1.1	K582I	Pathogenic	0.993
NPHS1	O60500-1.1	K582L	Pathogenic	0.995
NPHS1	O60500-1.1	K582M	Pathogenic	0.993
NPHS1	O60500-1.1	K582N	Pathogenic	0.962
NPHS1	O60500-1.1	K582P	Pathogenic	0.993
NPHS1	O60500-1.1	K582Q	Pathogenic	0.978
NPHS1	O60500-1.1	K582R	Pathogenic	0.946
NPHS1	O60500-1.1	K582S	Pathogenic	0.99
NPHS1	O60500-1.1	K582T	Pathogenic	0.985
NPHS1	O60500-1.1	K582V	Pathogenic	0.993
NPHS1	O60500-1.1	K582W	Pathogenic	0.998
NPHS1	O60500-1.1	K582Y	Pathogenic	0.982
NPHS1	O60500-1.1	E583A	Pathogenic	0.549
NPHS1	O60500-1.1	E583C	Neutral	0.39
NPHS1	O60500-1.1	E583D	Neutral	0.406
NPHS1	O60500-1.1	E583F	Pathogenic	0.773
NPHS1	O60500-1.1	E583G	Neutral	0.447
NPHS1	O60500-1.1	E583H	Neutral	0.39
NPHS1	O60500-1.1	E583I	Pathogenic	0.728
NPHS1	O60500-1.1	E583K	Neutral	0.434
NPHS1	O60500-1.1	E583L	Pathogenic	0.697
NPHS1	O60500-1.1	E583M	Pathogenic	0.63
NPHS1	O60500-1.1	E583N	Neutral	0.191
NPHS1	O60500-1.1	E583P	Pathogenic	0.566
NPHS1	O60500-1.1	E583Q	Neutral	0.434
NPHS1	O60500-1.1	E583R	Neutral	0.417
NPHS1	O60500-1.1	E583S	Neutral	0.485
NPHS1	O60500-1.1	E583T	Neutral	0.379
NPHS1	O60500-1.1	E583V	Pathogenic	0.563
NPHS1	O60500-1.1	E583W	Pathogenic	0.929
NPHS1	O60500-1.1	E583Y	Pathogenic	0.63
NPHS1	O60500-1.1	G584A	Pathogenic	0.686
NPHS1	O60500-1.1	G584C	Pathogenic	0.738
NPHS1	O60500-1.1	G584D	Pathogenic	0.837
NPHS1	O60500-1.1	G584E	Pathogenic	0.812
NPHS1	O60500-1.1	G584F	Pathogenic	0.967
NPHS1	O60500-1.1	G584H	Pathogenic	0.716
NPHS1	O60500-1.1	G584I	Pathogenic	0.94
NPHS1	O60500-1.1	G584K	Pathogenic	0.931
NPHS1	O60500-1.1	G584L	Pathogenic	0.931
NPHS1	O60500-1.1	G584M	Pathogenic	0.909
NPHS1	O60500-1.1	G584N	Pathogenic	0.87
NPHS1	O60500-1.1	G584P	Pathogenic	0.757
NPHS1	O60500-1.1	G584Q	Pathogenic	0.723
NPHS1	O60500-1.1	G584R	Pathogenic	0.949
NPHS1	O60500-1.1	G584S	Pathogenic	0.627
NPHS1	O60500-1.1	G584T	Pathogenic	0.627
NPHS1	O60500-1.1	G584V	Pathogenic	0.862
NPHS1	O60500-1.1	G584W	Pathogenic	0.994
NPHS1	O60500-1.1	G584Y	Pathogenic	0.909
NPHS1	O60500-1.1	E585A	Pathogenic	0.732
NPHS1	O60500-1.1	E585C	Pathogenic	0.589
NPHS1	O60500-1.1	E585D	Pathogenic	0.605
NPHS1	O60500-1.1	E585F	Pathogenic	0.884
NPHS1	O60500-1.1	E585G	Pathogenic	0.644
NPHS1	O60500-1.1	E585H	Pathogenic	0.589
NPHS1	O60500-1.1	E585I	Pathogenic	0.857
NPHS1	O60500-1.1	E585K	Pathogenic	0.632
NPHS1	O60500-1.1	E585L	Pathogenic	0.837
NPHS1	O60500-1.1	E585M	Pathogenic	0.793
NPHS1	O60500-1.1	E585N	Neutral	0.346
NPHS1	O60500-1.1	E585P	Pathogenic	0.745
NPHS1	O60500-1.1	E585Q	Pathogenic	0.632
NPHS1	O60500-1.1	E585R	Pathogenic	0.615
NPHS1	O60500-1.1	E585S	Pathogenic	0.679
NPHS1	O60500-1.1	E585T	Pathogenic	0.578
NPHS1	O60500-1.1	E585V	Pathogenic	0.742
NPHS1	O60500-1.1	E585W	Pathogenic	0.967
NPHS1	O60500-1.1	E585Y	Pathogenic	0.792
NPHS1	O60500-1.1	R586A	Pathogenic	0.866
NPHS1	O60500-1.1	R586C	Pathogenic	0.835
NPHS1	O60500-1.1	R586D	Neutral	0.332
NPHS1	O60500-1.1	R586E	Neutral	0.467
NPHS1	O60500-1.1	R586F	Pathogenic	0.841
NPHS1	O60500-1.1	R586G	Pathogenic	0.812
NPHS1	O60500-1.1	R586H	Pathogenic	0.69
NPHS1	O60500-1.1	R586I	Pathogenic	0.875
NPHS1	O60500-1.1	R586K	Neutral	0.385
NPHS1	O60500-1.1	R586L	Pathogenic	0.9
NPHS1	O60500-1.1	R586M	Pathogenic	0.87
NPHS1	O60500-1.1	R586N	Pathogenic	0.558
NPHS1	O60500-1.1	R586P	Pathogenic	0.823
NPHS1	O60500-1.1	R586Q	Pathogenic	0.684
NPHS1	O60500-1.1	R586S	Pathogenic	0.771
NPHS1	O60500-1.1	R586T	Pathogenic	0.765
NPHS1	O60500-1.1	R586V	Pathogenic	0.821
NPHS1	O60500-1.1	R586W	Pathogenic	0.917
NPHS1	O60500-1.1	R586Y	Pathogenic	0.667
NPHS1	O60500-1.1	L587A	Pathogenic	0.986
NPHS1	O60500-1.1	L587C	Pathogenic	0.942
NPHS1	O60500-1.1	L587D	Pathogenic	0.983
NPHS1	O60500-1.1	L587E	Pathogenic	0.979
NPHS1	O60500-1.1	L587F	Pathogenic	0.834
NPHS1	O60500-1.1	L587G	Pathogenic	0.981
NPHS1	O60500-1.1	L587H	Pathogenic	0.924
NPHS1	O60500-1.1	L587I	Pathogenic	0.898
NPHS1	O60500-1.1	L587K	Pathogenic	0.991
NPHS1	O60500-1.1	L587M	Pathogenic	0.938
NPHS1	O60500-1.1	L587N	Pathogenic	0.984
NPHS1	O60500-1.1	L587P	Pathogenic	0.908
NPHS1	O60500-1.1	L587Q	Pathogenic	0.971
NPHS1	O60500-1.1	L587R	Pathogenic	0.993
NPHS1	O60500-1.1	L587S	Pathogenic	0.985
NPHS1	O60500-1.1	L587T	Pathogenic	0.976
NPHS1	O60500-1.1	L587V	Pathogenic	0.942
NPHS1	O60500-1.1	L587W	Pathogenic	0.897
NPHS1	O60500-1.1	L587Y	Pathogenic	0.911
NPHS1	O60500-1.1	E588A	Neutral	0.23
NPHS1	O60500-1.1	E588C	Neutral	0.136
NPHS1	O60500-1.1	E588D	Neutral	0.144
NPHS1	O60500-1.1	E588F	Neutral	0.455
NPHS1	O60500-1.1	E588G	Neutral	0.166
NPHS1	O60500-1.1	E588H	Neutral	0.136
NPHS1	O60500-1.1	E588I	Neutral	0.397
NPHS1	O60500-1.1	E588K	Neutral	0.159
NPHS1	O60500-1.1	E588L	Neutral	0.361
NPHS1	O60500-1.1	E588M	Neutral	0.295
NPHS1	O60500-1.1	E588N	Neutral	0.055
NPHS1	O60500-1.1	E588P	Neutral	0.242
NPHS1	O60500-1.1	E588Q	Neutral	0.159
NPHS1	O60500-1.1	E588R	Neutral	0.149
NPHS1	O60500-1.1	E588S	Neutral	0.188
NPHS1	O60500-1.1	E588T	Neutral	0.13
NPHS1	O60500-1.1	E588V	Neutral	0.24
NPHS1	O60500-1.1	E588W	Pathogenic	0.763
NPHS1	O60500-1.1	E588Y	Neutral	0.295
NPHS1	O60500-1.1	G589A	Neutral	0.152
NPHS1	O60500-1.1	G589C	Neutral	0.187
NPHS1	O60500-1.1	G589D	Neutral	0.296
NPHS1	O60500-1.1	G589E	Neutral	0.261
NPHS1	O60500-1.1	G589F	Pathogenic	0.709
NPHS1	O60500-1.1	G589H	Neutral	0.171
NPHS1	O60500-1.1	G589I	Pathogenic	0.562
NPHS1	O60500-1.1	G589K	Pathogenic	0.525
NPHS1	O60500-1.1	G589L	Pathogenic	0.525
NPHS1	O60500-1.1	G589M	Neutral	0.45
NPHS1	O60500-1.1	G589N	Neutral	0.354
NPHS1	O60500-1.1	G589P	Neutral	0.203
NPHS1	O60500-1.1	G589Q	Neutral	0.176
NPHS1	O60500-1.1	G589R	Pathogenic	0.606
NPHS1	O60500-1.1	G589S	Neutral	0.121
NPHS1	O60500-1.1	G589T	Neutral	0.121
NPHS1	O60500-1.1	G589V	Neutral	0.338
NPHS1	O60500-1.1	G589W	Pathogenic	0.933
NPHS1	O60500-1.1	G589Y	Neutral	0.45
NPHS1	O60500-1.1	V590A	Pathogenic	0.627
NPHS1	O60500-1.1	V590C	Neutral	0.209
NPHS1	O60500-1.1	V590D	Pathogenic	0.589
NPHS1	O60500-1.1	V590E	Pathogenic	0.581
NPHS1	O60500-1.1	V590F	Neutral	0.361
NPHS1	O60500-1.1	V590G	Pathogenic	0.557
NPHS1	O60500-1.1	V590H	Neutral	0.268
NPHS1	O60500-1.1	V590I	Pathogenic	0.688
NPHS1	O60500-1.1	V590K	Pathogenic	0.812
NPHS1	O60500-1.1	V590L	Neutral	0.46
NPHS1	O60500-1.1	V590M	Neutral	0.297
NPHS1	O60500-1.1	V590N	Neutral	0.497
NPHS1	O60500-1.1	V590P	Neutral	0.193
NPHS1	O60500-1.1	V590Q	Neutral	0.456
NPHS1	O60500-1.1	V590R	Pathogenic	0.801
NPHS1	O60500-1.1	V590S	Pathogenic	0.523
NPHS1	O60500-1.1	V590T	Neutral	0.496
NPHS1	O60500-1.1	V590W	Neutral	0.495
NPHS1	O60500-1.1	V590Y	Neutral	0.29
NPHS1	O60500-1.1	A591C	Neutral	0.098
NPHS1	O60500-1.1	A591D	Neutral	0.091
NPHS1	O60500-1.1	A591E	Neutral	0.158
NPHS1	O60500-1.1	A591F	Neutral	0.341
NPHS1	O60500-1.1	A591G	Neutral	0.059
NPHS1	O60500-1.1	A591H	Neutral	0.047
NPHS1	O60500-1.1	A591I	Neutral	0.378
NPHS1	O60500-1.1	A591K	Neutral	0.37
NPHS1	O60500-1.1	A591L	Neutral	0.343
NPHS1	O60500-1.1	A591M	Neutral	0.206
NPHS1	O60500-1.1	A591N	Neutral	0.081
NPHS1	O60500-1.1	A591P	Neutral	0.051
NPHS1	O60500-1.1	A591Q	Neutral	0.102
NPHS1	O60500-1.1	A591R	Neutral	0.449
NPHS1	O60500-1.1	A591S	Neutral	0.068
NPHS1	O60500-1.1	A591T	Neutral	0.048
NPHS1	O60500-1.1	A591V	Neutral	0.195
NPHS1	O60500-1.1	A591W	Pathogenic	0.572
NPHS1	O60500-1.1	A591Y	Neutral	0.148
NPHS1	O60500-1.1	A592C	Neutral	0.028
NPHS1	O60500-1.1	A592D	Neutral	0.026
NPHS1	O60500-1.1	A592E	Neutral	0.047
NPHS1	O60500-1.1	A592F	Neutral	0.12
NPHS1	O60500-1.1	A592G	Neutral	0.016
NPHS1	O60500-1.1	A592H	Neutral	0.013
NPHS1	O60500-1.1	A592I	Neutral	0.138
NPHS1	O60500-1.1	A592K	Neutral	0.134
NPHS1	O60500-1.1	A592L	Neutral	0.121
NPHS1	O60500-1.1	A592M	Neutral	0.064
NPHS1	O60500-1.1	A592N	Neutral	0.023
NPHS1	O60500-1.1	A592P	Neutral	0.014
NPHS1	O60500-1.1	A592Q	Neutral	0.029
NPHS1	O60500-1.1	A592R	Neutral	0.177
NPHS1	O60500-1.1	A592S	Neutral	0.019
NPHS1	O60500-1.1	A592T	Neutral	0.013
NPHS1	O60500-1.1	A592V	Neutral	0.06
NPHS1	O60500-1.1	A592W	Neutral	0.26
NPHS1	O60500-1.1	A592Y	Neutral	0.044
NPHS1	O60500-1.1	P593A	Neutral	0.001
NPHS1	O60500-1.1	P593C	Neutral	0.0
NPHS1	O60500-1.1	P593D	Neutral	0.004
NPHS1	O60500-1.1	P593E	Neutral	0.005
NPHS1	O60500-1.1	P593F	Neutral	0.002
NPHS1	O60500-1.1	P593G	Neutral	0.002
NPHS1	O60500-1.1	P593H	Neutral	0.001
NPHS1	O60500-1.1	P593I	Neutral	0.002
NPHS1	O60500-1.1	P593K	Neutral	0.016
NPHS1	O60500-1.1	P593L	Neutral	0.002
NPHS1	O60500-1.1	P593M	Neutral	0.001
NPHS1	O60500-1.1	P593N	Neutral	0.002
NPHS1	O60500-1.1	P593Q	Neutral	0.003
NPHS1	O60500-1.1	P593R	Neutral	0.015
NPHS1	O60500-1.1	P593S	Neutral	0.002
NPHS1	O60500-1.1	P593T	Neutral	0.001
NPHS1	O60500-1.1	P593V	Neutral	0.001
NPHS1	O60500-1.1	P593W	Neutral	0.007
NPHS1	O60500-1.1	P593Y	Neutral	0.001
NPHS1	O60500-1.1	P594A	Neutral	0.071
NPHS1	O60500-1.1	P594C	Neutral	0.017
NPHS1	O60500-1.1	P594D	Neutral	0.185
NPHS1	O60500-1.1	P594E	Neutral	0.222
NPHS1	O60500-1.1	P594F	Neutral	0.094
NPHS1	O60500-1.1	P594G	Neutral	0.113
NPHS1	O60500-1.1	P594H	Neutral	0.07
NPHS1	O60500-1.1	P594I	Neutral	0.109
NPHS1	O60500-1.1	P594K	Neutral	0.471
NPHS1	O60500-1.1	P594L	Neutral	0.095
NPHS1	O60500-1.1	P594M	Neutral	0.072
NPHS1	O60500-1.1	P594N	Neutral	0.118
NPHS1	O60500-1.1	P594Q	Neutral	0.147
NPHS1	O60500-1.1	P594R	Neutral	0.453
NPHS1	O60500-1.1	P594S	Neutral	0.1
NPHS1	O60500-1.1	P594T	Neutral	0.049
NPHS1	O60500-1.1	P594V	Neutral	0.046
NPHS1	O60500-1.1	P594W	Neutral	0.286
NPHS1	O60500-1.1	P594Y	Neutral	0.049
NPHS1	O60500-1.1	R595A	Pathogenic	0.526
NPHS1	O60500-1.1	R595C	Neutral	0.465
NPHS1	O60500-1.1	R595D	Neutral	0.078
NPHS1	O60500-1.1	R595E	Neutral	0.131
NPHS1	O60500-1.1	R595F	Neutral	0.475
NPHS1	O60500-1.1	R595G	Neutral	0.424
NPHS1	O60500-1.1	R595H	Neutral	0.276
NPHS1	O60500-1.1	R595I	Pathogenic	0.546
NPHS1	O60500-1.1	R595K	Neutral	0.097
NPHS1	O60500-1.1	R595L	Pathogenic	0.606
NPHS1	O60500-1.1	R595M	Pathogenic	0.533
NPHS1	O60500-1.1	R595N	Neutral	0.177
NPHS1	O60500-1.1	R595P	Neutral	0.443
NPHS1	O60500-1.1	R595Q	Neutral	0.27
NPHS1	O60500-1.1	R595S	Neutral	0.366
NPHS1	O60500-1.1	R595T	Neutral	0.357
NPHS1	O60500-1.1	R595V	Neutral	0.44
NPHS1	O60500-1.1	R595W	Pathogenic	0.654
NPHS1	O60500-1.1	R595Y	Neutral	0.255
NPHS1	O60500-1.1	R596A	Neutral	0.034
NPHS1	O60500-1.1	R596C	Neutral	0.027
NPHS1	O60500-1.1	R596D	Neutral	0.003
NPHS1	O60500-1.1	R596E	Neutral	0.005
NPHS1	O60500-1.1	R596F	Neutral	0.028
NPHS1	O60500-1.1	R596G	Neutral	0.023
NPHS1	O60500-1.1	R596H	Neutral	0.012
NPHS1	O60500-1.1	R596I	Neutral	0.037
NPHS1	O60500-1.1	R596K	Neutral	0.003
NPHS1	O60500-1.1	R596L	Neutral	0.047
NPHS1	O60500-1.1	R596M	Neutral	0.035
NPHS1	O60500-1.1	R596N	Neutral	0.007
NPHS1	O60500-1.1	R596P	Neutral	0.025
NPHS1	O60500-1.1	R596Q	Neutral	0.012
NPHS1	O60500-1.1	R596S	Neutral	0.018
NPHS1	O60500-1.1	R596T	Neutral	0.018
NPHS1	O60500-1.1	R596V	Neutral	0.025
NPHS1	O60500-1.1	R596W	Neutral	0.057
NPHS1	O60500-1.1	R596Y	Neutral	0.011
NPHS1	O60500-1.1	A597C	Pathogenic	0.891
NPHS1	O60500-1.1	A597D	Pathogenic	0.883
NPHS1	O60500-1.1	A597E	Pathogenic	0.934
NPHS1	O60500-1.1	A597F	Pathogenic	0.975
NPHS1	O60500-1.1	A597G	Pathogenic	0.825
NPHS1	O60500-1.1	A597H	Pathogenic	0.788
NPHS1	O60500-1.1	A597I	Pathogenic	0.979
NPHS1	O60500-1.1	A597K	Pathogenic	0.978
NPHS1	O60500-1.1	A597L	Pathogenic	0.975
NPHS1	O60500-1.1	A597M	Pathogenic	0.951
NPHS1	O60500-1.1	A597N	Pathogenic	0.868
NPHS1	O60500-1.1	A597P	Pathogenic	0.802
NPHS1	O60500-1.1	A597Q	Pathogenic	0.895
NPHS1	O60500-1.1	A597R	Pathogenic	0.984
NPHS1	O60500-1.1	A597S	Pathogenic	0.846
NPHS1	O60500-1.1	A597T	Pathogenic	0.792
NPHS1	O60500-1.1	A597V	Pathogenic	0.948
NPHS1	O60500-1.1	A597W	Pathogenic	0.99
NPHS1	O60500-1.1	A597Y	Pathogenic	0.929
NPHS1	O60500-1.1	P598A	Neutral	0.103
NPHS1	O60500-1.1	P598C	Neutral	0.026
NPHS1	O60500-1.1	P598D	Neutral	0.253
NPHS1	O60500-1.1	P598E	Neutral	0.298
NPHS1	O60500-1.1	P598F	Neutral	0.134
NPHS1	O60500-1.1	P598G	Neutral	0.16
NPHS1	O60500-1.1	P598H	Neutral	0.101
NPHS1	O60500-1.1	P598I	Neutral	0.154
NPHS1	O60500-1.1	P598K	Pathogenic	0.57
NPHS1	O60500-1.1	P598L	Neutral	0.135
NPHS1	O60500-1.1	P598M	Neutral	0.104
NPHS1	O60500-1.1	P598N	Neutral	0.166
NPHS1	O60500-1.1	P598Q	Neutral	0.204
NPHS1	O60500-1.1	P598R	Pathogenic	0.553
NPHS1	O60500-1.1	P598S	Neutral	0.142
NPHS1	O60500-1.1	P598T	Neutral	0.071
NPHS1	O60500-1.1	P598V	Neutral	0.067
NPHS1	O60500-1.1	P598W	Neutral	0.374
NPHS1	O60500-1.1	P598Y	Neutral	0.072
NPHS1	O60500-1.1	F599A	Pathogenic	0.992
NPHS1	O60500-1.1	F599C	Pathogenic	0.968
NPHS1	O60500-1.1	F599D	Pathogenic	0.996
NPHS1	O60500-1.1	F599E	Pathogenic	0.992
NPHS1	O60500-1.1	F599G	Pathogenic	0.995
NPHS1	O60500-1.1	F599H	Pathogenic	0.987
NPHS1	O60500-1.1	F599I	Pathogenic	0.894
NPHS1	O60500-1.1	F599K	Pathogenic	0.992
NPHS1	O60500-1.1	F599L	Pathogenic	0.904
NPHS1	O60500-1.1	F599M	Pathogenic	0.95
NPHS1	O60500-1.1	F599N	Pathogenic	0.994
NPHS1	O60500-1.1	F599P	Pathogenic	0.948
NPHS1	O60500-1.1	F599Q	Pathogenic	0.984
NPHS1	O60500-1.1	F599R	Pathogenic	0.994
NPHS1	O60500-1.1	F599S	Pathogenic	0.995
NPHS1	O60500-1.1	F599T	Pathogenic	0.987
NPHS1	O60500-1.1	F599V	Pathogenic	0.953
NPHS1	O60500-1.1	F599W	Pathogenic	0.973
NPHS1	O60500-1.1	F599Y	Pathogenic	0.988
NPHS1	O60500-1.1	K600A	Pathogenic	0.943
NPHS1	O60500-1.1	K600C	Pathogenic	0.928
NPHS1	O60500-1.1	K600D	Pathogenic	0.653
NPHS1	O60500-1.1	K600E	Pathogenic	0.769
NPHS1	O60500-1.1	K600F	Pathogenic	0.931
NPHS1	O60500-1.1	K600G	Pathogenic	0.916
NPHS1	O60500-1.1	K600H	Pathogenic	0.792
NPHS1	O60500-1.1	K600I	Pathogenic	0.947
NPHS1	O60500-1.1	K600L	Pathogenic	0.958
NPHS1	O60500-1.1	K600M	Pathogenic	0.944
NPHS1	O60500-1.1	K600N	Pathogenic	0.762
NPHS1	O60500-1.1	K600P	Pathogenic	0.946
NPHS1	O60500-1.1	K600Q	Pathogenic	0.847
NPHS1	O60500-1.1	K600R	Pathogenic	0.689
NPHS1	O60500-1.1	K600S	Pathogenic	0.928
NPHS1	O60500-1.1	K600T	Pathogenic	0.892
NPHS1	O60500-1.1	K600V	Pathogenic	0.946
NPHS1	O60500-1.1	K600W	Pathogenic	0.981
NPHS1	O60500-1.1	K600Y	Pathogenic	0.871
NPHS1	O60500-1.1	G601A	Pathogenic	0.954
NPHS1	O60500-1.1	G601C	Pathogenic	0.964
NPHS1	O60500-1.1	G601D	Pathogenic	0.98
NPHS1	O60500-1.1	G601E	Pathogenic	0.976
NPHS1	O60500-1.1	G601F	Pathogenic	0.996
NPHS1	O60500-1.1	G601H	Pathogenic	0.96
NPHS1	O60500-1.1	G601I	Pathogenic	0.993
NPHS1	O60500-1.1	G601K	Pathogenic	0.992
NPHS1	O60500-1.1	G601L	Pathogenic	0.992
NPHS1	O60500-1.1	G601M	Pathogenic	0.99
NPHS1	O60500-1.1	G601N	Pathogenic	0.985
NPHS1	O60500-1.1	G601P	Pathogenic	0.967
NPHS1	O60500-1.1	G601Q	Pathogenic	0.961
NPHS1	O60500-1.1	G601R	Pathogenic	0.994
NPHS1	O60500-1.1	G601S	Pathogenic	0.941
NPHS1	O60500-1.1	G601T	Pathogenic	0.941
NPHS1	O60500-1.1	G601V	Pathogenic	0.983
NPHS1	O60500-1.1	G601W	Pathogenic	0.999
NPHS1	O60500-1.1	G601Y	Pathogenic	0.99
NPHS1	O60500-1.1	S602A	Neutral	0.063
NPHS1	O60500-1.1	S602C	Neutral	0.088
NPHS1	O60500-1.1	S602D	Neutral	0.096
NPHS1	O60500-1.1	S602E	Neutral	0.118
NPHS1	O60500-1.1	S602F	Neutral	0.406
NPHS1	O60500-1.1	S602G	Neutral	0.042
NPHS1	O60500-1.1	S602H	Neutral	0.055
NPHS1	O60500-1.1	S602I	Neutral	0.35
NPHS1	O60500-1.1	S602K	Neutral	0.294
NPHS1	O60500-1.1	S602L	Neutral	0.317
NPHS1	O60500-1.1	S602M	Neutral	0.256
NPHS1	O60500-1.1	S602N	Neutral	0.122
NPHS1	O60500-1.1	S602P	Neutral	0.067
NPHS1	O60500-1.1	S602Q	Neutral	0.074
NPHS1	O60500-1.1	S602R	Neutral	0.279
NPHS1	O60500-1.1	S602T	Neutral	0.079
NPHS1	O60500-1.1	S602V	Neutral	0.126
NPHS1	O60500-1.1	S602W	Pathogenic	0.639
NPHS1	O60500-1.1	S602Y	Neutral	0.187
NPHS1	O60500-1.1	A603C	Neutral	0.22
NPHS1	O60500-1.1	A603D	Neutral	0.206
NPHS1	O60500-1.1	A603E	Neutral	0.327
NPHS1	O60500-1.1	A603F	Pathogenic	0.572
NPHS1	O60500-1.1	A603G	Neutral	0.14
NPHS1	O60500-1.1	A603H	Neutral	0.114
NPHS1	O60500-1.1	A603I	Pathogenic	0.611
NPHS1	O60500-1.1	A603K	Pathogenic	0.603
NPHS1	O60500-1.1	A603L	Pathogenic	0.574
NPHS1	O60500-1.1	A603M	Neutral	0.402
NPHS1	O60500-1.1	A603N	Neutral	0.185
NPHS1	O60500-1.1	A603P	Neutral	0.123
NPHS1	O60500-1.1	A603Q	Neutral	0.227
NPHS1	O60500-1.1	A603R	Pathogenic	0.678
NPHS1	O60500-1.1	A603S	Neutral	0.159
NPHS1	O60500-1.1	A603T	Neutral	0.116
NPHS1	O60500-1.1	A603V	Neutral	0.385
NPHS1	O60500-1.1	A603W	Pathogenic	0.776
NPHS1	O60500-1.1	A603Y	Neutral	0.31
NPHS1	O60500-1.1	A604C	Neutral	0.185
NPHS1	O60500-1.1	A604D	Neutral	0.173
NPHS1	O60500-1.1	A604E	Neutral	0.282
NPHS1	O60500-1.1	A604F	Pathogenic	0.519
NPHS1	O60500-1.1	A604G	Neutral	0.116
NPHS1	O60500-1.1	A604H	Neutral	0.094
NPHS1	O60500-1.1	A604I	Pathogenic	0.559
NPHS1	O60500-1.1	A604K	Pathogenic	0.55
NPHS1	O60500-1.1	A604L	Pathogenic	0.521
NPHS1	O60500-1.1	A604M	Neutral	0.351
NPHS1	O60500-1.1	A604N	Neutral	0.155
NPHS1	O60500-1.1	A604P	Neutral	0.101
NPHS1	O60500-1.1	A604Q	Neutral	0.192
NPHS1	O60500-1.1	A604R	Pathogenic	0.63
NPHS1	O60500-1.1	A604S	Neutral	0.132
NPHS1	O60500-1.1	A604T	Neutral	0.096
NPHS1	O60500-1.1	A604V	Neutral	0.335
NPHS1	O60500-1.1	A604W	Pathogenic	0.736
NPHS1	O60500-1.1	A604Y	Neutral	0.266
NPHS1	O60500-1.1	A605C	Neutral	0.126
NPHS1	O60500-1.1	A605D	Neutral	0.117
NPHS1	O60500-1.1	A605E	Neutral	0.199
NPHS1	O60500-1.1	A605F	Neutral	0.406
NPHS1	O60500-1.1	A605G	Neutral	0.077
NPHS1	O60500-1.1	A605H	Neutral	0.062
NPHS1	O60500-1.1	A605I	Neutral	0.446
NPHS1	O60500-1.1	A605K	Neutral	0.437
NPHS1	O60500-1.1	A605L	Neutral	0.408
NPHS1	O60500-1.1	A605M	Neutral	0.256
NPHS1	O60500-1.1	A605N	Neutral	0.104
NPHS1	O60500-1.1	A605P	Neutral	0.067
NPHS1	O60500-1.1	A605Q	Neutral	0.131
NPHS1	O60500-1.1	A605R	Pathogenic	0.519
NPHS1	O60500-1.1	A605S	Neutral	0.088
NPHS1	O60500-1.1	A605T	Neutral	0.063
NPHS1	O60500-1.1	A605V	Neutral	0.242
NPHS1	O60500-1.1	A605W	Pathogenic	0.639
NPHS1	O60500-1.1	A605Y	Neutral	0.187
NPHS1	O60500-1.1	R606A	Pathogenic	0.819
NPHS1	O60500-1.1	R606C	Pathogenic	0.78
NPHS1	O60500-1.1	R606D	Neutral	0.257
NPHS1	O60500-1.1	R606E	Neutral	0.38
NPHS1	O60500-1.1	R606F	Pathogenic	0.787
NPHS1	O60500-1.1	R606G	Pathogenic	0.751
NPHS1	O60500-1.1	R606H	Pathogenic	0.609
NPHS1	O60500-1.1	R606I	Pathogenic	0.831
NPHS1	O60500-1.1	R606K	Neutral	0.304
NPHS1	O60500-1.1	R606L	Pathogenic	0.863
NPHS1	O60500-1.1	R606M	Pathogenic	0.823
NPHS1	O60500-1.1	R606N	Neutral	0.468
NPHS1	O60500-1.1	R606P	Pathogenic	0.765
NPHS1	O60500-1.1	R606Q	Pathogenic	0.602
NPHS1	O60500-1.1	R606S	Pathogenic	0.702
NPHS1	O60500-1.1	R606T	Pathogenic	0.694
NPHS1	O60500-1.1	R606V	Pathogenic	0.763
NPHS1	O60500-1.1	R606W	Pathogenic	0.885
NPHS1	O60500-1.1	R606Y	Pathogenic	0.583
NPHS1	O60500-1.1	S607A	Neutral	0.11
NPHS1	O60500-1.1	S607C	Neutral	0.152
NPHS1	O60500-1.1	S607D	Neutral	0.164
NPHS1	O60500-1.1	S607E	Neutral	0.198
NPHS1	O60500-1.1	S607F	Pathogenic	0.559
NPHS1	O60500-1.1	S607G	Neutral	0.076
NPHS1	O60500-1.1	S607H	Neutral	0.097
NPHS1	O60500-1.1	S607I	Neutral	0.5
NPHS1	O60500-1.1	S607K	Neutral	0.435
NPHS1	O60500-1.1	S607L	Neutral	0.462
NPHS1	O60500-1.1	S607M	Neutral	0.389
NPHS1	O60500-1.1	S607N	Neutral	0.204
NPHS1	O60500-1.1	S607P	Neutral	0.117
NPHS1	O60500-1.1	S607Q	Neutral	0.13
NPHS1	O60500-1.1	S607R	Neutral	0.418
NPHS1	O60500-1.1	S607T	Neutral	0.138
NPHS1	O60500-1.1	S607V	Neutral	0.21
NPHS1	O60500-1.1	S607W	Pathogenic	0.766
NPHS1	O60500-1.1	S607Y	Neutral	0.299
NPHS1	O60500-1.1	V608A	Pathogenic	0.823
NPHS1	O60500-1.1	V608C	Neutral	0.421
NPHS1	O60500-1.1	V608D	Pathogenic	0.798
NPHS1	O60500-1.1	V608E	Pathogenic	0.792
NPHS1	O60500-1.1	V608F	Pathogenic	0.609
NPHS1	O60500-1.1	V608G	Pathogenic	0.776
NPHS1	O60500-1.1	V608H	Pathogenic	0.502
NPHS1	O60500-1.1	V608I	Pathogenic	0.859
NPHS1	O60500-1.1	V608K	Pathogenic	0.923
NPHS1	O60500-1.1	V608L	Pathogenic	0.701
NPHS1	O60500-1.1	V608M	Pathogenic	0.539
NPHS1	O60500-1.1	V608N	Pathogenic	0.732
NPHS1	O60500-1.1	V608P	Neutral	0.397
NPHS1	O60500-1.1	V608Q	Pathogenic	0.698
NPHS1	O60500-1.1	V608R	Pathogenic	0.917
NPHS1	O60500-1.1	V608S	Pathogenic	0.752
NPHS1	O60500-1.1	V608T	Pathogenic	0.73
NPHS1	O60500-1.1	V608W	Pathogenic	0.73
NPHS1	O60500-1.1	V608Y	Pathogenic	0.529
NPHS1	O60500-1.1	L609A	Neutral	0.072
NPHS1	O60500-1.1	L609C	Neutral	0.018
NPHS1	O60500-1.1	L609D	Neutral	0.062
NPHS1	O60500-1.1	L609E	Neutral	0.05
NPHS1	O60500-1.1	L609F	Neutral	0.006
NPHS1	O60500-1.1	L609G	Neutral	0.054
NPHS1	O60500-1.1	L609H	Neutral	0.013
NPHS1	O60500-1.1	L609I	Neutral	0.01
NPHS1	O60500-1.1	L609K	Neutral	0.107
NPHS1	O60500-1.1	L609M	Neutral	0.017
NPHS1	O60500-1.1	L609N	Neutral	0.063
NPHS1	O60500-1.1	L609P	Neutral	0.011
NPHS1	O60500-1.1	L609Q	Neutral	0.036
NPHS1	O60500-1.1	L609R	Neutral	0.143
NPHS1	O60500-1.1	L609S	Neutral	0.07
NPHS1	O60500-1.1	L609T	Neutral	0.043
NPHS1	O60500-1.1	L609V	Neutral	0.018
NPHS1	O60500-1.1	L609W	Neutral	0.01
NPHS1	O60500-1.1	L609Y	Neutral	0.011
NPHS1	O60500-1.1	L610A	Pathogenic	0.903
NPHS1	O60500-1.1	L610C	Pathogenic	0.686
NPHS1	O60500-1.1	L610D	Pathogenic	0.888
NPHS1	O60500-1.1	L610E	Pathogenic	0.864
NPHS1	O60500-1.1	L610F	Neutral	0.403
NPHS1	O60500-1.1	L610G	Pathogenic	0.875
NPHS1	O60500-1.1	L610H	Pathogenic	0.621
NPHS1	O60500-1.1	L610I	Pathogenic	0.542
NPHS1	O60500-1.1	L610K	Pathogenic	0.936
NPHS1	O60500-1.1	L610M	Pathogenic	0.671
NPHS1	O60500-1.1	L610N	Pathogenic	0.891
NPHS1	O60500-1.1	L610P	Pathogenic	0.57
NPHS1	O60500-1.1	L610Q	Pathogenic	0.819
NPHS1	O60500-1.1	L610R	Pathogenic	0.953
NPHS1	O60500-1.1	L610S	Pathogenic	0.901
NPHS1	O60500-1.1	L610T	Pathogenic	0.845
NPHS1	O60500-1.1	L610V	Pathogenic	0.687
NPHS1	O60500-1.1	L610W	Pathogenic	0.539
NPHS1	O60500-1.1	L610Y	Pathogenic	0.579
NPHS1	O60500-1.1	Q611A	Neutral	0.005
NPHS1	O60500-1.1	Q611C	Neutral	0.004
NPHS1	O60500-1.1	Q611D	Neutral	0.004
NPHS1	O60500-1.1	Q611E	Neutral	0.005
NPHS1	O60500-1.1	Q611F	Neutral	0.01
NPHS1	O60500-1.1	Q611G	Neutral	0.003
NPHS1	O60500-1.1	Q611H	Neutral	0.002
NPHS1	O60500-1.1	Q611I	Neutral	0.008
NPHS1	O60500-1.1	Q611K	Neutral	0.008
NPHS1	O60500-1.1	Q611L	Neutral	0.011
NPHS1	O60500-1.1	Q611M	Neutral	0.012
NPHS1	O60500-1.1	Q611N	Neutral	0.003
NPHS1	O60500-1.1	Q611P	Neutral	0.005
NPHS1	O60500-1.1	Q611R	Neutral	0.011
NPHS1	O60500-1.1	Q611S	Neutral	0.004
NPHS1	O60500-1.1	Q611T	Neutral	0.002
NPHS1	O60500-1.1	Q611V	Neutral	0.005
NPHS1	O60500-1.1	Q611W	Neutral	0.057
NPHS1	O60500-1.1	Q611Y	Neutral	0.008
NPHS1	O60500-1.1	V612A	Neutral	0.17
NPHS1	O60500-1.1	V612C	Neutral	0.031
NPHS1	O60500-1.1	V612D	Neutral	0.148
NPHS1	O60500-1.1	V612E	Neutral	0.144
NPHS1	O60500-1.1	V612F	Neutral	0.064
NPHS1	O60500-1.1	V612G	Neutral	0.133
NPHS1	O60500-1.1	V612H	Neutral	0.043
NPHS1	O60500-1.1	V612I	Neutral	0.211
NPHS1	O60500-1.1	V612K	Neutral	0.344
NPHS1	O60500-1.1	V612L	Neutral	0.094
NPHS1	O60500-1.1	V612M	Neutral	0.049
NPHS1	O60500-1.1	V612N	Neutral	0.107
NPHS1	O60500-1.1	V612P	Neutral	0.028
NPHS1	O60500-1.1	V612Q	Neutral	0.092
NPHS1	O60500-1.1	V612R	Neutral	0.329
NPHS1	O60500-1.1	V612S	Neutral	0.118
NPHS1	O60500-1.1	V612T	Neutral	0.107
NPHS1	O60500-1.1	V612W	Neutral	0.106
NPHS1	O60500-1.1	V612Y	Neutral	0.047
NPHS1	O60500-1.1	S613A	Pathogenic	0.716
NPHS1	O60500-1.1	S613C	Pathogenic	0.785
NPHS1	O60500-1.1	S613D	Pathogenic	0.8
NPHS1	O60500-1.1	S613E	Pathogenic	0.834
NPHS1	O60500-1.1	S613F	Pathogenic	0.963
NPHS1	O60500-1.1	S613G	Pathogenic	0.626
NPHS1	O60500-1.1	S613H	Pathogenic	0.687
NPHS1	O60500-1.1	S613I	Pathogenic	0.953
NPHS1	O60500-1.1	S613K	Pathogenic	0.94
NPHS1	O60500-1.1	S613L	Pathogenic	0.946
NPHS1	O60500-1.1	S613M	Pathogenic	0.928
NPHS1	O60500-1.1	S613N	Pathogenic	0.839
NPHS1	O60500-1.1	S613P	Pathogenic	0.73
NPHS1	O60500-1.1	S613Q	Pathogenic	0.752
NPHS1	O60500-1.1	S613R	Pathogenic	0.936
NPHS1	O60500-1.1	S613T	Pathogenic	0.765
NPHS1	O60500-1.1	S613V	Pathogenic	0.845
NPHS1	O60500-1.1	S613W	Pathogenic	0.985
NPHS1	O60500-1.1	S613Y	Pathogenic	0.897
NPHS1	O60500-1.1	S614A	Pathogenic	0.951
NPHS1	O60500-1.1	S614C	Pathogenic	0.966
NPHS1	O60500-1.1	S614D	Pathogenic	0.969
NPHS1	O60500-1.1	S614E	Pathogenic	0.975
NPHS1	O60500-1.1	S614F	Pathogenic	0.995
NPHS1	O60500-1.1	S614G	Pathogenic	0.929
NPHS1	O60500-1.1	S614H	Pathogenic	0.945
NPHS1	O60500-1.1	S614I	Pathogenic	0.994
NPHS1	O60500-1.1	S614K	Pathogenic	0.992
NPHS1	O60500-1.1	S614L	Pathogenic	0.993
NPHS1	O60500-1.1	S614M	Pathogenic	0.99
NPHS1	O60500-1.1	S614N	Pathogenic	0.976
NPHS1	O60500-1.1	S614P	Pathogenic	0.955
NPHS1	O60500-1.1	S614Q	Pathogenic	0.959
NPHS1	O60500-1.1	S614R	Pathogenic	0.991
NPHS1	O60500-1.1	S614T	Pathogenic	0.962
NPHS1	O60500-1.1	S614V	Pathogenic	0.977
NPHS1	O60500-1.1	S614W	Pathogenic	0.998
NPHS1	O60500-1.1	S614Y	Pathogenic	0.985
NPHS1	O60500-1.1	R615A	Neutral	0.335
NPHS1	O60500-1.1	R615C	Neutral	0.283
NPHS1	O60500-1.1	R615D	Neutral	0.037
NPHS1	O60500-1.1	R615E	Neutral	0.064
NPHS1	O60500-1.1	R615F	Neutral	0.291
NPHS1	O60500-1.1	R615G	Neutral	0.251
NPHS1	O60500-1.1	R615H	Neutral	0.148
NPHS1	O60500-1.1	R615I	Neutral	0.353
NPHS1	O60500-1.1	R615K	Neutral	0.046
NPHS1	O60500-1.1	R615L	Neutral	0.411
NPHS1	O60500-1.1	R615M	Neutral	0.341
NPHS1	O60500-1.1	R615N	Neutral	0.089
NPHS1	O60500-1.1	R615P	Neutral	0.265
NPHS1	O60500-1.1	R615Q	Neutral	0.144
NPHS1	O60500-1.1	R615S	Neutral	0.207
NPHS1	O60500-1.1	R615T	Neutral	0.201
NPHS1	O60500-1.1	R615V	Neutral	0.263
NPHS1	O60500-1.1	R615W	Neutral	0.462
NPHS1	O60500-1.1	R615Y	Neutral	0.134
NPHS1	O60500-1.1	D616A	Pathogenic	0.964
NPHS1	O60500-1.1	D616C	Pathogenic	0.969
NPHS1	O60500-1.1	D616E	Pathogenic	0.965
NPHS1	O60500-1.1	D616F	Pathogenic	0.996
NPHS1	O60500-1.1	D616G	Pathogenic	0.975
NPHS1	O60500-1.1	D616H	Pathogenic	0.97
NPHS1	O60500-1.1	D616I	Pathogenic	0.995
NPHS1	O60500-1.1	D616K	Pathogenic	0.947
NPHS1	O60500-1.1	D616L	Pathogenic	0.992
NPHS1	O60500-1.1	D616M	Pathogenic	0.989
NPHS1	O60500-1.1	D616N	Pathogenic	0.936
NPHS1	O60500-1.1	D616P	Pathogenic	0.977
NPHS1	O60500-1.1	D616Q	Pathogenic	0.963
NPHS1	O60500-1.1	D616R	Pathogenic	0.943
NPHS1	O60500-1.1	D616S	Pathogenic	0.968
NPHS1	O60500-1.1	D616T	Pathogenic	0.956
NPHS1	O60500-1.1	D616V	Pathogenic	0.982
NPHS1	O60500-1.1	D616W	Pathogenic	0.999
NPHS1	O60500-1.1	D616Y	Pathogenic	0.989
NPHS1	O60500-1.1	H617A	Pathogenic	0.954
NPHS1	O60500-1.1	H617C	Pathogenic	0.961
NPHS1	O60500-1.1	H617D	Pathogenic	0.981
NPHS1	O60500-1.1	H617E	Pathogenic	0.977
NPHS1	O60500-1.1	H617F	Pathogenic	0.992
NPHS1	O60500-1.1	H617G	Pathogenic	0.968
NPHS1	O60500-1.1	H617I	Pathogenic	0.978
NPHS1	O60500-1.1	H617K	Pathogenic	0.983
NPHS1	O60500-1.1	H617L	Pathogenic	0.975
NPHS1	O60500-1.1	H617M	Pathogenic	0.966
NPHS1	O60500-1.1	H617N	Pathogenic	0.988
NPHS1	O60500-1.1	H617P	Pathogenic	0.957
NPHS1	O60500-1.1	H617Q	Pathogenic	0.952
NPHS1	O60500-1.1	H617R	Pathogenic	0.992
NPHS1	O60500-1.1	H617S	Pathogenic	0.964
NPHS1	O60500-1.1	H617T	Pathogenic	0.913
NPHS1	O60500-1.1	H617V	Pathogenic	0.957
NPHS1	O60500-1.1	H617W	Pathogenic	0.997
NPHS1	O60500-1.1	H617Y	Pathogenic	0.993
NPHS1	O60500-1.1	G618A	Pathogenic	0.658
NPHS1	O60500-1.1	G618C	Pathogenic	0.713
NPHS1	O60500-1.1	G618D	Pathogenic	0.819
NPHS1	O60500-1.1	G618E	Pathogenic	0.792
NPHS1	O60500-1.1	G618F	Pathogenic	0.963
NPHS1	O60500-1.1	G618H	Pathogenic	0.69
NPHS1	O60500-1.1	G618I	Pathogenic	0.933
NPHS1	O60500-1.1	G618K	Pathogenic	0.923
NPHS1	O60500-1.1	G618L	Pathogenic	0.923
NPHS1	O60500-1.1	G618M	Pathogenic	0.898
NPHS1	O60500-1.1	G618N	Pathogenic	0.855
NPHS1	O60500-1.1	G618P	Pathogenic	0.733
NPHS1	O60500-1.1	G618Q	Pathogenic	0.698
NPHS1	O60500-1.1	G618R	Pathogenic	0.943
NPHS1	O60500-1.1	G618S	Pathogenic	0.597
NPHS1	O60500-1.1	G618T	Pathogenic	0.597
NPHS1	O60500-1.1	G618V	Pathogenic	0.847
NPHS1	O60500-1.1	G618W	Pathogenic	0.993
NPHS1	O60500-1.1	G618Y	Pathogenic	0.898
NPHS1	O60500-1.1	Q619A	Neutral	0.065
NPHS1	O60500-1.1	Q619C	Neutral	0.051
NPHS1	O60500-1.1	Q619D	Neutral	0.057
NPHS1	O60500-1.1	Q619E	Neutral	0.067
NPHS1	O60500-1.1	Q619F	Neutral	0.132
NPHS1	O60500-1.1	Q619G	Neutral	0.044
NPHS1	O60500-1.1	Q619H	Neutral	0.028
NPHS1	O60500-1.1	Q619I	Neutral	0.107
NPHS1	O60500-1.1	Q619K	Neutral	0.106
NPHS1	O60500-1.1	Q619L	Neutral	0.133
NPHS1	O60500-1.1	Q619M	Neutral	0.145
NPHS1	O60500-1.1	Q619N	Neutral	0.04
NPHS1	O60500-1.1	Q619P	Neutral	0.069
NPHS1	O60500-1.1	Q619R	Neutral	0.142
NPHS1	O60500-1.1	Q619S	Neutral	0.051
NPHS1	O60500-1.1	Q619T	Neutral	0.033
NPHS1	O60500-1.1	Q619V	Neutral	0.068
NPHS1	O60500-1.1	Q619W	Neutral	0.467
NPHS1	O60500-1.1	Q619Y	Neutral	0.102
NPHS1	O60500-1.1	R620A	Pathogenic	0.996
NPHS1	O60500-1.1	R620C	Pathogenic	0.995
NPHS1	O60500-1.1	R620D	Pathogenic	0.948
NPHS1	O60500-1.1	R620E	Pathogenic	0.97
NPHS1	O60500-1.1	R620F	Pathogenic	0.995
NPHS1	O60500-1.1	R620G	Pathogenic	0.994
NPHS1	O60500-1.1	R620H	Pathogenic	0.988
NPHS1	O60500-1.1	R620I	Pathogenic	0.996
NPHS1	O60500-1.1	R620K	Pathogenic	0.958
NPHS1	O60500-1.1	R620L	Pathogenic	0.997
NPHS1	O60500-1.1	R620M	Pathogenic	0.996
NPHS1	O60500-1.1	R620N	Pathogenic	0.979
NPHS1	O60500-1.1	R620P	Pathogenic	0.994
NPHS1	O60500-1.1	R620Q	Pathogenic	0.988
NPHS1	O60500-1.1	R620S	Pathogenic	0.992
NPHS1	O60500-1.1	R620T	Pathogenic	0.992
NPHS1	O60500-1.1	R620V	Pathogenic	0.994
NPHS1	O60500-1.1	R620W	Pathogenic	0.998
NPHS1	O60500-1.1	R620Y	Pathogenic	0.987
NPHS1	O60500-1.1	V621A	Pathogenic	0.991
NPHS1	O60500-1.1	V621C	Pathogenic	0.946
NPHS1	O60500-1.1	V621D	Pathogenic	0.989
NPHS1	O60500-1.1	V621E	Pathogenic	0.989
NPHS1	O60500-1.1	V621F	Pathogenic	0.974
NPHS1	O60500-1.1	V621G	Pathogenic	0.988
NPHS1	O60500-1.1	V621H	Pathogenic	0.96
NPHS1	O60500-1.1	V621I	Pathogenic	0.993
NPHS1	O60500-1.1	V621K	Pathogenic	0.996
NPHS1	O60500-1.1	V621L	Pathogenic	0.982
NPHS1	O60500-1.1	V621M	Pathogenic	0.965
NPHS1	O60500-1.1	V621N	Pathogenic	0.985
NPHS1	O60500-1.1	V621P	Pathogenic	0.94
NPHS1	O60500-1.1	V621Q	Pathogenic	0.982
NPHS1	O60500-1.1	V621R	Pathogenic	0.996
NPHS1	O60500-1.1	V621S	Pathogenic	0.986
NPHS1	O60500-1.1	V621T	Pathogenic	0.985
NPHS1	O60500-1.1	V621W	Pathogenic	0.985
NPHS1	O60500-1.1	V621Y	Pathogenic	0.964
NPHS1	O60500-1.1	T622A	Pathogenic	0.719
NPHS1	O60500-1.1	T622C	Pathogenic	0.749
NPHS1	O60500-1.1	T622D	Pathogenic	0.806
NPHS1	O60500-1.1	T622E	Pathogenic	0.826
NPHS1	O60500-1.1	T622F	Pathogenic	0.938
NPHS1	O60500-1.1	T622G	Pathogenic	0.71
NPHS1	O60500-1.1	T622H	Pathogenic	0.556
NPHS1	O60500-1.1	T622I	Pathogenic	0.947
NPHS1	O60500-1.1	T622K	Pathogenic	0.937
NPHS1	O60500-1.1	T622L	Pathogenic	0.939
NPHS1	O60500-1.1	T622M	Pathogenic	0.884
NPHS1	O60500-1.1	T622N	Pathogenic	0.831
NPHS1	O60500-1.1	T622P	Pathogenic	0.647
NPHS1	O60500-1.1	T622Q	Pathogenic	0.742
NPHS1	O60500-1.1	T622R	Pathogenic	0.954
NPHS1	O60500-1.1	T622S	Pathogenic	0.826
NPHS1	O60500-1.1	T622V	Pathogenic	0.877
NPHS1	O60500-1.1	T622W	Pathogenic	0.983
NPHS1	O60500-1.1	T622Y	Pathogenic	0.836
NPHS1	O60500-1.1	C623A	Pathogenic	0.977
NPHS1	O60500-1.1	C623D	Pathogenic	0.978
NPHS1	O60500-1.1	C623E	Pathogenic	0.975
NPHS1	O60500-1.1	C623F	Pathogenic	0.979
NPHS1	O60500-1.1	C623G	Pathogenic	0.969
NPHS1	O60500-1.1	C623H	Pathogenic	0.957
NPHS1	O60500-1.1	C623I	Pathogenic	0.982
NPHS1	O60500-1.1	C623K	Pathogenic	0.994
NPHS1	O60500-1.1	C623L	Pathogenic	0.979
NPHS1	O60500-1.1	C623M	Pathogenic	0.959
NPHS1	O60500-1.1	C623N	Pathogenic	0.975
NPHS1	O60500-1.1	C623P	Pathogenic	0.829
NPHS1	O60500-1.1	C623Q	Pathogenic	0.972
NPHS1	O60500-1.1	C623R	Pathogenic	0.996
NPHS1	O60500-1.1	C623S	Pathogenic	0.976
NPHS1	O60500-1.1	C623T	Pathogenic	0.958
NPHS1	O60500-1.1	C623V	Pathogenic	0.936
NPHS1	O60500-1.1	C623W	Pathogenic	0.994
NPHS1	O60500-1.1	C623Y	Pathogenic	0.944
NPHS1	O60500-1.1	R624A	Pathogenic	0.533
NPHS1	O60500-1.1	R624C	Neutral	0.472
NPHS1	O60500-1.1	R624D	Neutral	0.08
NPHS1	O60500-1.1	R624E	Neutral	0.134
NPHS1	O60500-1.1	R624F	Neutral	0.483
NPHS1	O60500-1.1	R624G	Neutral	0.432
NPHS1	O60500-1.1	R624H	Neutral	0.282
NPHS1	O60500-1.1	R624I	Pathogenic	0.553
NPHS1	O60500-1.1	R624K	Neutral	0.099
NPHS1	O60500-1.1	R624L	Pathogenic	0.613
NPHS1	O60500-1.1	R624M	Pathogenic	0.54
NPHS1	O60500-1.1	R624N	Neutral	0.182
NPHS1	O60500-1.1	R624P	Neutral	0.451
NPHS1	O60500-1.1	R624Q	Neutral	0.276
NPHS1	O60500-1.1	R624S	Neutral	0.373
NPHS1	O60500-1.1	R624T	Neutral	0.364
NPHS1	O60500-1.1	R624V	Neutral	0.448
NPHS1	O60500-1.1	R624W	Pathogenic	0.661
NPHS1	O60500-1.1	R624Y	Neutral	0.26
NPHS1	O60500-1.1	A625C	Pathogenic	0.988
NPHS1	O60500-1.1	A625D	Pathogenic	0.987
NPHS1	O60500-1.1	A625E	Pathogenic	0.993
NPHS1	O60500-1.1	A625F	Pathogenic	0.997
NPHS1	O60500-1.1	A625G	Pathogenic	0.979
NPHS1	O60500-1.1	A625H	Pathogenic	0.973
NPHS1	O60500-1.1	A625I	Pathogenic	0.998
NPHS1	O60500-1.1	A625K	Pathogenic	0.998
NPHS1	O60500-1.1	A625L	Pathogenic	0.997
NPHS1	O60500-1.1	A625M	Pathogenic	0.995
NPHS1	O60500-1.1	A625N	Pathogenic	0.985
NPHS1	O60500-1.1	A625P	Pathogenic	0.975
NPHS1	O60500-1.1	A625Q	Pathogenic	0.988
NPHS1	O60500-1.1	A625R	Pathogenic	0.998
NPHS1	O60500-1.1	A625S	Pathogenic	0.982
NPHS1	O60500-1.1	A625T	Pathogenic	0.974
NPHS1	O60500-1.1	A625V	Pathogenic	0.994
NPHS1	O60500-1.1	A625W	Pathogenic	0.999
NPHS1	O60500-1.1	A625Y	Pathogenic	0.992
NPHS1	O60500-1.1	H626A	Pathogenic	0.769
NPHS1	O60500-1.1	H626C	Pathogenic	0.796
NPHS1	O60500-1.1	H626D	Pathogenic	0.892
NPHS1	O60500-1.1	H626E	Pathogenic	0.869
NPHS1	O60500-1.1	H626F	Pathogenic	0.953
NPHS1	O60500-1.1	H626G	Pathogenic	0.83
NPHS1	O60500-1.1	H626I	Pathogenic	0.877
NPHS1	O60500-1.1	H626K	Pathogenic	0.901
NPHS1	O60500-1.1	H626L	Pathogenic	0.86
NPHS1	O60500-1.1	H626M	Pathogenic	0.82
NPHS1	O60500-1.1	H626N	Pathogenic	0.927
NPHS1	O60500-1.1	H626P	Pathogenic	0.781
NPHS1	O60500-1.1	H626Q	Pathogenic	0.76
NPHS1	O60500-1.1	H626R	Pathogenic	0.95
NPHS1	O60500-1.1	H626S	Pathogenic	0.81
NPHS1	O60500-1.1	H626T	Pathogenic	0.626
NPHS1	O60500-1.1	H626V	Pathogenic	0.779
NPHS1	O60500-1.1	H626W	Pathogenic	0.981
NPHS1	O60500-1.1	H626Y	Pathogenic	0.957
NPHS1	O60500-1.1	S627A	Pathogenic	0.937
NPHS1	O60500-1.1	S627C	Pathogenic	0.956
NPHS1	O60500-1.1	S627D	Pathogenic	0.96
NPHS1	O60500-1.1	S627E	Pathogenic	0.968
NPHS1	O60500-1.1	S627F	Pathogenic	0.994
NPHS1	O60500-1.1	S627G	Pathogenic	0.908
NPHS1	O60500-1.1	S627H	Pathogenic	0.929
NPHS1	O60500-1.1	S627I	Pathogenic	0.992
NPHS1	O60500-1.1	S627K	Pathogenic	0.989
NPHS1	O60500-1.1	S627L	Pathogenic	0.99
NPHS1	O60500-1.1	S627M	Pathogenic	0.987
NPHS1	O60500-1.1	S627N	Pathogenic	0.969
NPHS1	O60500-1.1	S627P	Pathogenic	0.941
NPHS1	O60500-1.1	S627Q	Pathogenic	0.947
NPHS1	O60500-1.1	S627R	Pathogenic	0.989
NPHS1	O60500-1.1	S627T	Pathogenic	0.951
NPHS1	O60500-1.1	S627V	Pathogenic	0.97
NPHS1	O60500-1.1	S627W	Pathogenic	0.997
NPHS1	O60500-1.1	S627Y	Pathogenic	0.981
NPHS1	O60500-1.1	A628C	Neutral	0.007
NPHS1	O60500-1.1	A628D	Neutral	0.007
NPHS1	O60500-1.1	A628E	Neutral	0.012
NPHS1	O60500-1.1	A628F	Neutral	0.033
NPHS1	O60500-1.1	A628G	Neutral	0.004
NPHS1	O60500-1.1	A628H	Neutral	0.003
NPHS1	O60500-1.1	A628I	Neutral	0.038
NPHS1	O60500-1.1	A628K	Neutral	0.037
NPHS1	O60500-1.1	A628L	Neutral	0.033
NPHS1	O60500-1.1	A628M	Neutral	0.017
NPHS1	O60500-1.1	A628N	Neutral	0.006
NPHS1	O60500-1.1	A628P	Neutral	0.004
NPHS1	O60500-1.1	A628Q	Neutral	0.007
NPHS1	O60500-1.1	A628R	Neutral	0.051
NPHS1	O60500-1.1	A628S	Neutral	0.005
NPHS1	O60500-1.1	A628T	Neutral	0.003
NPHS1	O60500-1.1	A628V	Neutral	0.016
NPHS1	O60500-1.1	A628W	Neutral	0.081
NPHS1	O60500-1.1	A628Y	Neutral	0.011
NPHS1	O60500-1.1	E629A	Neutral	0.094
NPHS1	O60500-1.1	E629C	Neutral	0.052
NPHS1	O60500-1.1	E629D	Neutral	0.055
NPHS1	O60500-1.1	E629F	Neutral	0.225
NPHS1	O60500-1.1	E629G	Neutral	0.065
NPHS1	O60500-1.1	E629H	Neutral	0.052
NPHS1	O60500-1.1	E629I	Neutral	0.186
NPHS1	O60500-1.1	E629K	Neutral	0.061
NPHS1	O60500-1.1	E629L	Neutral	0.164
NPHS1	O60500-1.1	E629M	Neutral	0.127
NPHS1	O60500-1.1	E629N	Neutral	0.02
NPHS1	O60500-1.1	E629P	Neutral	0.1
NPHS1	O60500-1.1	E629Q	Neutral	0.061
NPHS1	O60500-1.1	E629R	Neutral	0.057
NPHS1	O60500-1.1	E629S	Neutral	0.074
NPHS1	O60500-1.1	E629T	Neutral	0.049
NPHS1	O60500-1.1	E629V	Neutral	0.099
NPHS1	O60500-1.1	E629W	Pathogenic	0.528
NPHS1	O60500-1.1	E629Y	Neutral	0.127
NPHS1	O60500-1.1	L630A	Pathogenic	0.993
NPHS1	O60500-1.1	L630C	Pathogenic	0.971
NPHS1	O60500-1.1	L630D	Pathogenic	0.992
NPHS1	O60500-1.1	L630E	Pathogenic	0.99
NPHS1	O60500-1.1	L630F	Pathogenic	0.913
NPHS1	O60500-1.1	L630G	Pathogenic	0.991
NPHS1	O60500-1.1	L630H	Pathogenic	0.962
NPHS1	O60500-1.1	L630I	Pathogenic	0.948
NPHS1	O60500-1.1	L630K	Pathogenic	0.996
NPHS1	O60500-1.1	L630M	Pathogenic	0.969
NPHS1	O60500-1.1	L630N	Pathogenic	0.992
NPHS1	O60500-1.1	L630P	Pathogenic	0.954
NPHS1	O60500-1.1	L630Q	Pathogenic	0.986
NPHS1	O60500-1.1	L630R	Pathogenic	0.997
NPHS1	O60500-1.1	L630S	Pathogenic	0.993
NPHS1	O60500-1.1	L630T	Pathogenic	0.988
NPHS1	O60500-1.1	L630V	Pathogenic	0.971
NPHS1	O60500-1.1	L630W	Pathogenic	0.948
NPHS1	O60500-1.1	L630Y	Pathogenic	0.955
NPHS1	O60500-1.1	R631A	Neutral	0.414
NPHS1	O60500-1.1	R631C	Neutral	0.356
NPHS1	O60500-1.1	R631D	Neutral	0.051
NPHS1	O60500-1.1	R631E	Neutral	0.087
NPHS1	O60500-1.1	R631F	Neutral	0.366
NPHS1	O60500-1.1	R631G	Neutral	0.32
NPHS1	O60500-1.1	R631H	Neutral	0.196
NPHS1	O60500-1.1	R631I	Neutral	0.434
NPHS1	O60500-1.1	R631K	Neutral	0.064
NPHS1	O60500-1.1	R631L	Neutral	0.495
NPHS1	O60500-1.1	R631M	Neutral	0.421
NPHS1	O60500-1.1	R631N	Neutral	0.121
NPHS1	O60500-1.1	R631P	Neutral	0.337
NPHS1	O60500-1.1	R631Q	Neutral	0.191
NPHS1	O60500-1.1	R631S	Neutral	0.269
NPHS1	O60500-1.1	R631T	Neutral	0.262
NPHS1	O60500-1.1	R631V	Neutral	0.334
NPHS1	O60500-1.1	R631W	Pathogenic	0.546
NPHS1	O60500-1.1	R631Y	Neutral	0.179
NPHS1	O60500-1.1	E632A	Pathogenic	0.992
NPHS1	O60500-1.1	E632C	Pathogenic	0.984
NPHS1	O60500-1.1	E632D	Pathogenic	0.985
NPHS1	O60500-1.1	E632F	Pathogenic	0.997
NPHS1	O60500-1.1	E632G	Pathogenic	0.987
NPHS1	O60500-1.1	E632H	Pathogenic	0.984
NPHS1	O60500-1.1	E632I	Pathogenic	0.996
NPHS1	O60500-1.1	E632K	Pathogenic	0.987
NPHS1	O60500-1.1	E632L	Pathogenic	0.996
NPHS1	O60500-1.1	E632M	Pathogenic	0.994
NPHS1	O60500-1.1	E632N	Pathogenic	0.958
NPHS1	O60500-1.1	E632P	Pathogenic	0.992
NPHS1	O60500-1.1	E632Q	Pathogenic	0.987
NPHS1	O60500-1.1	E632R	Pathogenic	0.986
NPHS1	O60500-1.1	E632S	Pathogenic	0.989
NPHS1	O60500-1.1	E632T	Pathogenic	0.983
NPHS1	O60500-1.1	E632V	Pathogenic	0.992
NPHS1	O60500-1.1	E632W	Pathogenic	0.999
NPHS1	O60500-1.1	E632Y	Pathogenic	0.994
NPHS1	O60500-1.1	T633A	Neutral	0.318
NPHS1	O60500-1.1	T633C	Neutral	0.352
NPHS1	O60500-1.1	T633D	Neutral	0.43
NPHS1	O60500-1.1	T633E	Neutral	0.463
NPHS1	O60500-1.1	T633F	Pathogenic	0.734
NPHS1	O60500-1.1	T633G	Neutral	0.308
NPHS1	O60500-1.1	T633H	Neutral	0.186
NPHS1	O60500-1.1	T633I	Pathogenic	0.765
NPHS1	O60500-1.1	T633K	Pathogenic	0.729
NPHS1	O60500-1.1	T633L	Pathogenic	0.736
NPHS1	O60500-1.1	T633M	Pathogenic	0.581
NPHS1	O60500-1.1	T633N	Neutral	0.473
NPHS1	O60500-1.1	T633P	Neutral	0.25
NPHS1	O60500-1.1	T633Q	Neutral	0.343
NPHS1	O60500-1.1	T633R	Pathogenic	0.789
NPHS1	O60500-1.1	T633S	Neutral	0.463
NPHS1	O60500-1.1	T633V	Pathogenic	0.564
NPHS1	O60500-1.1	T633W	Pathogenic	0.914
NPHS1	O60500-1.1	T633Y	Neutral	0.482
NPHS1	O60500-1.1	V634A	Pathogenic	0.81
NPHS1	O60500-1.1	V634C	Neutral	0.401
NPHS1	O60500-1.1	V634D	Pathogenic	0.784
NPHS1	O60500-1.1	V634E	Pathogenic	0.779
NPHS1	O60500-1.1	V634F	Pathogenic	0.589
NPHS1	O60500-1.1	V634G	Pathogenic	0.761
NPHS1	O60500-1.1	V634H	Neutral	0.481
NPHS1	O60500-1.1	V634I	Pathogenic	0.848
NPHS1	O60500-1.1	V634K	Pathogenic	0.916
NPHS1	O60500-1.1	V634L	Pathogenic	0.684
NPHS1	O60500-1.1	V634M	Pathogenic	0.518
NPHS1	O60500-1.1	V634N	Pathogenic	0.715
NPHS1	O60500-1.1	V634P	Neutral	0.377
NPHS1	O60500-1.1	V634Q	Pathogenic	0.68
NPHS1	O60500-1.1	V634R	Pathogenic	0.911
NPHS1	O60500-1.1	V634S	Pathogenic	0.736
NPHS1	O60500-1.1	V634T	Pathogenic	0.714
NPHS1	O60500-1.1	V634W	Pathogenic	0.713
NPHS1	O60500-1.1	V634Y	Pathogenic	0.509
NPHS1	O60500-1.1	S635A	Pathogenic	0.626
NPHS1	O60500-1.1	S635C	Pathogenic	0.708
NPHS1	O60500-1.1	S635D	Pathogenic	0.727
NPHS1	O60500-1.1	S635E	Pathogenic	0.77
NPHS1	O60500-1.1	S635F	Pathogenic	0.945
NPHS1	O60500-1.1	S635G	Pathogenic	0.527
NPHS1	O60500-1.1	S635H	Pathogenic	0.593
NPHS1	O60500-1.1	S635I	Pathogenic	0.931
NPHS1	O60500-1.1	S635K	Pathogenic	0.913
NPHS1	O60500-1.1	S635L	Pathogenic	0.921
NPHS1	O60500-1.1	S635M	Pathogenic	0.896
NPHS1	O60500-1.1	S635N	Pathogenic	0.777
NPHS1	O60500-1.1	S635P	Pathogenic	0.643
NPHS1	O60500-1.1	S635Q	Pathogenic	0.669
NPHS1	O60500-1.1	S635R	Pathogenic	0.907
NPHS1	O60500-1.1	S635T	Pathogenic	0.684
NPHS1	O60500-1.1	S635V	Pathogenic	0.783
NPHS1	O60500-1.1	S635W	Pathogenic	0.978
NPHS1	O60500-1.1	S635Y	Pathogenic	0.852
NPHS1	O60500-1.1	S636A	Neutral	0.039
NPHS1	O60500-1.1	S636C	Neutral	0.056
NPHS1	O60500-1.1	S636D	Neutral	0.061
NPHS1	O60500-1.1	S636E	Neutral	0.075
NPHS1	O60500-1.1	S636F	Neutral	0.295
NPHS1	O60500-1.1	S636G	Neutral	0.026
NPHS1	O60500-1.1	S636H	Neutral	0.034
NPHS1	O60500-1.1	S636I	Neutral	0.248
NPHS1	O60500-1.1	S636K	Neutral	0.203
NPHS1	O60500-1.1	S636L	Neutral	0.221
NPHS1	O60500-1.1	S636M	Neutral	0.174
NPHS1	O60500-1.1	S636N	Neutral	0.078
NPHS1	O60500-1.1	S636P	Neutral	0.042
NPHS1	O60500-1.1	S636Q	Neutral	0.047
NPHS1	O60500-1.1	S636R	Neutral	0.192
NPHS1	O60500-1.1	S636T	Neutral	0.05
NPHS1	O60500-1.1	S636V	Neutral	0.081
NPHS1	O60500-1.1	S636W	Pathogenic	0.52
NPHS1	O60500-1.1	S636Y	Neutral	0.123
NPHS1	O60500-1.1	F637A	Pathogenic	0.999
NPHS1	O60500-1.1	F637C	Pathogenic	0.996
NPHS1	O60500-1.1	F637D	Pathogenic	1.0
NPHS1	O60500-1.1	F637E	Pathogenic	0.999
NPHS1	O60500-1.1	F637G	Pathogenic	0.999
NPHS1	O60500-1.1	F637H	Pathogenic	0.999
NPHS1	O60500-1.1	F637I	Pathogenic	0.987
NPHS1	O60500-1.1	F637K	Pathogenic	0.999
NPHS1	O60500-1.1	F637L	Pathogenic	0.988
NPHS1	O60500-1.1	F637M	Pathogenic	0.994
NPHS1	O60500-1.1	F637N	Pathogenic	0.999
NPHS1	O60500-1.1	F637P	Pathogenic	0.994
NPHS1	O60500-1.1	F637Q	Pathogenic	0.998
NPHS1	O60500-1.1	F637R	Pathogenic	0.999
NPHS1	O60500-1.1	F637S	Pathogenic	0.999
NPHS1	O60500-1.1	F637T	Pathogenic	0.999
NPHS1	O60500-1.1	F637V	Pathogenic	0.995
NPHS1	O60500-1.1	F637W	Pathogenic	0.997
NPHS1	O60500-1.1	F637Y	Pathogenic	0.999
NPHS1	O60500-1.1	Y638A	Pathogenic	0.996
NPHS1	O60500-1.1	Y638C	Pathogenic	0.985
NPHS1	O60500-1.1	Y638D	Pathogenic	0.998
NPHS1	O60500-1.1	Y638E	Pathogenic	0.997
NPHS1	O60500-1.1	Y638F	Pathogenic	0.998
NPHS1	O60500-1.1	Y638G	Pathogenic	0.998
NPHS1	O60500-1.1	Y638H	Pathogenic	0.998
NPHS1	O60500-1.1	Y638I	Pathogenic	0.993
NPHS1	O60500-1.1	Y638K	Pathogenic	0.997
NPHS1	O60500-1.1	Y638L	Pathogenic	0.991
NPHS1	O60500-1.1	Y638M	Pathogenic	0.983
NPHS1	O60500-1.1	Y638N	Pathogenic	0.998
NPHS1	O60500-1.1	Y638P	Pathogenic	0.982
NPHS1	O60500-1.1	Y638Q	Pathogenic	0.996
NPHS1	O60500-1.1	Y638R	Pathogenic	0.997
NPHS1	O60500-1.1	Y638S	Pathogenic	0.997
NPHS1	O60500-1.1	Y638T	Pathogenic	0.993
NPHS1	O60500-1.1	Y638V	Pathogenic	0.989
NPHS1	O60500-1.1	Y638W	Pathogenic	0.999
NPHS1	O60500-1.1	R639A	Pathogenic	0.777
NPHS1	O60500-1.1	R639C	Pathogenic	0.732
NPHS1	O60500-1.1	R639D	Neutral	0.211
NPHS1	O60500-1.1	R639E	Neutral	0.321
NPHS1	O60500-1.1	R639F	Pathogenic	0.74
NPHS1	O60500-1.1	R639G	Pathogenic	0.699
NPHS1	O60500-1.1	R639H	Pathogenic	0.546
NPHS1	O60500-1.1	R639I	Pathogenic	0.791
NPHS1	O60500-1.1	R639K	Neutral	0.252
NPHS1	O60500-1.1	R639L	Pathogenic	0.829
NPHS1	O60500-1.1	R639M	Pathogenic	0.782
NPHS1	O60500-1.1	R639N	Neutral	0.404
NPHS1	O60500-1.1	R639P	Pathogenic	0.715
NPHS1	O60500-1.1	R639Q	Pathogenic	0.538
NPHS1	O60500-1.1	R639S	Pathogenic	0.645
NPHS1	O60500-1.1	R639T	Pathogenic	0.636
NPHS1	O60500-1.1	R639V	Pathogenic	0.712
NPHS1	O60500-1.1	R639W	Pathogenic	0.856
NPHS1	O60500-1.1	R639Y	Pathogenic	0.518
NPHS1	O60500-1.1	L640A	Pathogenic	0.962
NPHS1	O60500-1.1	L640C	Pathogenic	0.855
NPHS1	O60500-1.1	L640D	Pathogenic	0.956
NPHS1	O60500-1.1	L640E	Pathogenic	0.945
NPHS1	O60500-1.1	L640F	Pathogenic	0.646
NPHS1	O60500-1.1	L640G	Pathogenic	0.95
NPHS1	O60500-1.1	L640H	Pathogenic	0.816
NPHS1	O60500-1.1	L640I	Pathogenic	0.762
NPHS1	O60500-1.1	L640K	Pathogenic	0.975
NPHS1	O60500-1.1	L640M	Pathogenic	0.847
NPHS1	O60500-1.1	L640N	Pathogenic	0.957
NPHS1	O60500-1.1	L640P	Pathogenic	0.782
NPHS1	O60500-1.1	L640Q	Pathogenic	0.925
NPHS1	O60500-1.1	L640R	Pathogenic	0.982
NPHS1	O60500-1.1	L640S	Pathogenic	0.961
NPHS1	O60500-1.1	L640T	Pathogenic	0.937
NPHS1	O60500-1.1	L640V	Pathogenic	0.856
NPHS1	O60500-1.1	L640W	Pathogenic	0.76
NPHS1	O60500-1.1	L640Y	Pathogenic	0.788
NPHS1	O60500-1.1	N641A	Pathogenic	0.974
NPHS1	O60500-1.1	N641C	Pathogenic	0.978
NPHS1	O60500-1.1	N641D	Pathogenic	0.959
NPHS1	O60500-1.1	N641E	Pathogenic	0.94
NPHS1	O60500-1.1	N641F	Pathogenic	0.997
NPHS1	O60500-1.1	N641G	Pathogenic	0.988
NPHS1	O60500-1.1	N641H	Pathogenic	0.988
NPHS1	O60500-1.1	N641I	Pathogenic	0.996
NPHS1	O60500-1.1	N641K	Pathogenic	0.98
NPHS1	O60500-1.1	N641L	Pathogenic	0.995
NPHS1	O60500-1.1	N641M	Pathogenic	0.993
NPHS1	O60500-1.1	N641P	Pathogenic	0.976
NPHS1	O60500-1.1	N641Q	Pathogenic	0.967
NPHS1	O60500-1.1	N641R	Pathogenic	0.985
NPHS1	O60500-1.1	N641S	Pathogenic	0.985
NPHS1	O60500-1.1	N641T	Pathogenic	0.977
NPHS1	O60500-1.1	N641V	Pathogenic	0.984
NPHS1	O60500-1.1	N641W	Pathogenic	0.999
NPHS1	O60500-1.1	N641Y	Pathogenic	0.993
NPHS1	O60500-1.1	V642A	Pathogenic	0.94
NPHS1	O60500-1.1	V642C	Pathogenic	0.71
NPHS1	O60500-1.1	V642D	Pathogenic	0.93
NPHS1	O60500-1.1	V642E	Pathogenic	0.928
NPHS1	O60500-1.1	V642F	Pathogenic	0.84
NPHS1	O60500-1.1	V642G	Pathogenic	0.921
NPHS1	O60500-1.1	V642H	Pathogenic	0.772
NPHS1	O60500-1.1	V642I	Pathogenic	0.953
NPHS1	O60500-1.1	V642K	Pathogenic	0.976
NPHS1	O60500-1.1	V642L	Pathogenic	0.887
NPHS1	O60500-1.1	V642M	Pathogenic	0.797
NPHS1	O60500-1.1	V642N	Pathogenic	0.902
NPHS1	O60500-1.1	V642P	Pathogenic	0.688
NPHS1	O60500-1.1	V642Q	Pathogenic	0.886
NPHS1	O60500-1.1	V642R	Pathogenic	0.974
NPHS1	O60500-1.1	V642S	Pathogenic	0.91
NPHS1	O60500-1.1	V642T	Pathogenic	0.901
NPHS1	O60500-1.1	V642W	Pathogenic	0.901
NPHS1	O60500-1.1	V642Y	Pathogenic	0.791
NPHS1	O60500-1.1	L643A	Pathogenic	0.979
NPHS1	O60500-1.1	L643C	Pathogenic	0.918
NPHS1	O60500-1.1	L643D	Pathogenic	0.976
NPHS1	O60500-1.1	L643E	Pathogenic	0.97
NPHS1	O60500-1.1	L643F	Pathogenic	0.774
NPHS1	O60500-1.1	L643G	Pathogenic	0.973
NPHS1	O60500-1.1	L643H	Pathogenic	0.893
NPHS1	O60500-1.1	L643I	Pathogenic	0.857
NPHS1	O60500-1.1	L643K	Pathogenic	0.987
NPHS1	O60500-1.1	L643M	Pathogenic	0.912
NPHS1	O60500-1.1	L643N	Pathogenic	0.977
NPHS1	O60500-1.1	L643P	Pathogenic	0.871
NPHS1	O60500-1.1	L643Q	Pathogenic	0.958
NPHS1	O60500-1.1	L643R	Pathogenic	0.99
NPHS1	O60500-1.1	L643S	Pathogenic	0.979
NPHS1	O60500-1.1	L643T	Pathogenic	0.965
NPHS1	O60500-1.1	L643V	Pathogenic	0.918
NPHS1	O60500-1.1	L643W	Pathogenic	0.856
NPHS1	O60500-1.1	L643Y	Pathogenic	0.875
NPHS1	O60500-1.1	Y644A	Pathogenic	0.991
NPHS1	O60500-1.1	Y644C	Pathogenic	0.966
NPHS1	O60500-1.1	Y644D	Pathogenic	0.995
NPHS1	O60500-1.1	Y644E	Pathogenic	0.994
NPHS1	O60500-1.1	Y644F	Pathogenic	0.995
NPHS1	O60500-1.1	Y644G	Pathogenic	0.995
NPHS1	O60500-1.1	Y644H	Pathogenic	0.995
NPHS1	O60500-1.1	Y644I	Pathogenic	0.983
NPHS1	O60500-1.1	Y644K	Pathogenic	0.994
NPHS1	O60500-1.1	Y644L	Pathogenic	0.98
NPHS1	O60500-1.1	Y644M	Pathogenic	0.961
NPHS1	O60500-1.1	Y644N	Pathogenic	0.995
NPHS1	O60500-1.1	Y644P	Pathogenic	0.96
NPHS1	O60500-1.1	Y644Q	Pathogenic	0.992
NPHS1	O60500-1.1	Y644R	Pathogenic	0.994
NPHS1	O60500-1.1	Y644S	Pathogenic	0.994
NPHS1	O60500-1.1	Y644T	Pathogenic	0.985
NPHS1	O60500-1.1	Y644V	Pathogenic	0.974
NPHS1	O60500-1.1	Y644W	Pathogenic	0.998
NPHS1	O60500-1.1	R645A	Pathogenic	0.892
NPHS1	O60500-1.1	R645C	Pathogenic	0.866
NPHS1	O60500-1.1	R645D	Neutral	0.387
NPHS1	O60500-1.1	R645E	Pathogenic	0.527
NPHS1	O60500-1.1	R645F	Pathogenic	0.871
NPHS1	O60500-1.1	R645G	Pathogenic	0.845
NPHS1	O60500-1.1	R645H	Pathogenic	0.739
NPHS1	O60500-1.1	R645I	Pathogenic	0.899
NPHS1	O60500-1.1	R645K	Neutral	0.443
NPHS1	O60500-1.1	R645L	Pathogenic	0.919
NPHS1	O60500-1.1	R645M	Pathogenic	0.894
NPHS1	O60500-1.1	R645N	Pathogenic	0.615
NPHS1	O60500-1.1	R645P	Pathogenic	0.855
NPHS1	O60500-1.1	R645Q	Pathogenic	0.733
NPHS1	O60500-1.1	R645S	Pathogenic	0.811
NPHS1	O60500-1.1	R645T	Pathogenic	0.805
NPHS1	O60500-1.1	R645V	Pathogenic	0.854
NPHS1	O60500-1.1	R645W	Pathogenic	0.933
NPHS1	O60500-1.1	R645Y	Pathogenic	0.717
NPHS1	O60500-1.1	P646A	Pathogenic	0.963
NPHS1	O60500-1.1	P646C	Pathogenic	0.858
NPHS1	O60500-1.1	P646D	Pathogenic	0.987
NPHS1	O60500-1.1	P646E	Pathogenic	0.99
NPHS1	O60500-1.1	P646F	Pathogenic	0.973
NPHS1	O60500-1.1	P646G	Pathogenic	0.978
NPHS1	O60500-1.1	P646H	Pathogenic	0.962
NPHS1	O60500-1.1	P646I	Pathogenic	0.977
NPHS1	O60500-1.1	P646K	Pathogenic	0.997
NPHS1	O60500-1.1	P646L	Pathogenic	0.973
NPHS1	O60500-1.1	P646M	Pathogenic	0.964
NPHS1	O60500-1.1	P646N	Pathogenic	0.978
NPHS1	O60500-1.1	P646Q	Pathogenic	0.983
NPHS1	O60500-1.1	P646R	Pathogenic	0.996
NPHS1	O60500-1.1	P646S	Pathogenic	0.974
NPHS1	O60500-1.1	P646T	Pathogenic	0.946
NPHS1	O60500-1.1	P646V	Pathogenic	0.943
NPHS1	O60500-1.1	P646W	Pathogenic	0.993
NPHS1	O60500-1.1	P646Y	Pathogenic	0.947
NPHS1	O60500-1.1	E647A	Pathogenic	0.988
NPHS1	O60500-1.1	E647C	Pathogenic	0.977
NPHS1	O60500-1.1	E647D	Pathogenic	0.979
NPHS1	O60500-1.1	E647F	Pathogenic	0.996
NPHS1	O60500-1.1	E647G	Pathogenic	0.982
NPHS1	O60500-1.1	E647H	Pathogenic	0.978
NPHS1	O60500-1.1	E647I	Pathogenic	0.995
NPHS1	O60500-1.1	E647K	Pathogenic	0.981
NPHS1	O60500-1.1	E647L	Pathogenic	0.994
NPHS1	O60500-1.1	E647M	Pathogenic	0.991
NPHS1	O60500-1.1	E647N	Pathogenic	0.941
NPHS1	O60500-1.1	E647P	Pathogenic	0.989
NPHS1	O60500-1.1	E647Q	Pathogenic	0.981
NPHS1	O60500-1.1	E647R	Pathogenic	0.98
NPHS1	O60500-1.1	E647S	Pathogenic	0.985
NPHS1	O60500-1.1	E647T	Pathogenic	0.976
NPHS1	O60500-1.1	E647V	Pathogenic	0.989
NPHS1	O60500-1.1	E647W	Pathogenic	0.999
NPHS1	O60500-1.1	E647Y	Pathogenic	0.991
NPHS1	O60500-1.1	F648A	Pathogenic	0.999
NPHS1	O60500-1.1	F648C	Pathogenic	0.996
NPHS1	O60500-1.1	F648D	Pathogenic	0.999
NPHS1	O60500-1.1	F648E	Pathogenic	0.999
NPHS1	O60500-1.1	F648G	Pathogenic	0.999
NPHS1	O60500-1.1	F648H	Pathogenic	0.998
NPHS1	O60500-1.1	F648I	Pathogenic	0.985
NPHS1	O60500-1.1	F648K	Pathogenic	0.999
NPHS1	O60500-1.1	F648L	Pathogenic	0.987
NPHS1	O60500-1.1	F648M	Pathogenic	0.993
NPHS1	O60500-1.1	F648N	Pathogenic	0.999
NPHS1	O60500-1.1	F648P	Pathogenic	0.993
NPHS1	O60500-1.1	F648Q	Pathogenic	0.998
NPHS1	O60500-1.1	F648R	Pathogenic	0.999
NPHS1	O60500-1.1	F648S	Pathogenic	0.999
NPHS1	O60500-1.1	F648T	Pathogenic	0.998
NPHS1	O60500-1.1	F648V	Pathogenic	0.994
NPHS1	O60500-1.1	F648W	Pathogenic	0.997
NPHS1	O60500-1.1	F648Y	Pathogenic	0.998
NPHS1	O60500-1.1	L649A	Pathogenic	0.804
NPHS1	O60500-1.1	L649C	Neutral	0.49
NPHS1	O60500-1.1	L649D	Pathogenic	0.777
NPHS1	O60500-1.1	L649E	Pathogenic	0.736
NPHS1	O60500-1.1	L649F	Neutral	0.228
NPHS1	O60500-1.1	L649G	Pathogenic	0.754
NPHS1	O60500-1.1	L649H	Neutral	0.418
NPHS1	O60500-1.1	L649I	Neutral	0.341
NPHS1	O60500-1.1	L649K	Pathogenic	0.865
NPHS1	O60500-1.1	L649M	Neutral	0.472
NPHS1	O60500-1.1	L649N	Pathogenic	0.782
NPHS1	O60500-1.1	L649P	Neutral	0.367
NPHS1	O60500-1.1	L649Q	Pathogenic	0.665
NPHS1	O60500-1.1	L649R	Pathogenic	0.899
NPHS1	O60500-1.1	L649S	Pathogenic	0.799
NPHS1	O60500-1.1	L649T	Pathogenic	0.705
NPHS1	O60500-1.1	L649V	Neutral	0.49
NPHS1	O60500-1.1	L649W	Neutral	0.339
NPHS1	O60500-1.1	L649Y	Neutral	0.376
NPHS1	O60500-1.1	G650A	Neutral	0.203
NPHS1	O60500-1.1	G650C	Neutral	0.247
NPHS1	O60500-1.1	G650D	Neutral	0.374
NPHS1	O60500-1.1	G650E	Neutral	0.335
NPHS1	O60500-1.1	G650F	Pathogenic	0.776
NPHS1	O60500-1.1	G650H	Neutral	0.227
NPHS1	O60500-1.1	G650I	Pathogenic	0.646
NPHS1	O60500-1.1	G650K	Pathogenic	0.611
NPHS1	O60500-1.1	G650L	Pathogenic	0.611
NPHS1	O60500-1.1	G650M	Pathogenic	0.538
NPHS1	O60500-1.1	G650N	Neutral	0.438
NPHS1	O60500-1.1	G650P	Neutral	0.266
NPHS1	O60500-1.1	G650Q	Neutral	0.233
NPHS1	O60500-1.1	G650R	Pathogenic	0.686
NPHS1	O60500-1.1	G650S	Neutral	0.164
NPHS1	O60500-1.1	G650T	Neutral	0.164
NPHS1	O60500-1.1	G650V	Neutral	0.421
NPHS1	O60500-1.1	G650W	Pathogenic	0.952
NPHS1	O60500-1.1	G650Y	Pathogenic	0.537
NPHS1	O60500-1.1	E651A	Pathogenic	0.899
NPHS1	O60500-1.1	E651C	Pathogenic	0.823
NPHS1	O60500-1.1	E651D	Pathogenic	0.832
NPHS1	O60500-1.1	E651F	Pathogenic	0.961
NPHS1	O60500-1.1	E651G	Pathogenic	0.855
NPHS1	O60500-1.1	E651H	Pathogenic	0.823
NPHS1	O60500-1.1	E651I	Pathogenic	0.951
NPHS1	O60500-1.1	E651K	Pathogenic	0.848
NPHS1	O60500-1.1	E651L	Pathogenic	0.944
NPHS1	O60500-1.1	E651M	Pathogenic	0.925
NPHS1	O60500-1.1	E651N	Pathogenic	0.633
NPHS1	O60500-1.1	E651P	Pathogenic	0.905
NPHS1	O60500-1.1	E651Q	Pathogenic	0.848
NPHS1	O60500-1.1	E651R	Pathogenic	0.839
NPHS1	O60500-1.1	E651S	Pathogenic	0.873
NPHS1	O60500-1.1	E651T	Pathogenic	0.816
NPHS1	O60500-1.1	E651V	Pathogenic	0.904
NPHS1	O60500-1.1	E651W	Pathogenic	0.99
NPHS1	O60500-1.1	E651Y	Pathogenic	0.925
NPHS1	O60500-1.1	Q652A	Pathogenic	0.992
NPHS1	O60500-1.1	Q652C	Pathogenic	0.99
NPHS1	O60500-1.1	Q652D	Pathogenic	0.991
NPHS1	O60500-1.1	Q652E	Pathogenic	0.993
NPHS1	O60500-1.1	Q652F	Pathogenic	0.997
NPHS1	O60500-1.1	Q652G	Pathogenic	0.989
NPHS1	O60500-1.1	Q652H	Pathogenic	0.982
NPHS1	O60500-1.1	Q652I	Pathogenic	0.996
NPHS1	O60500-1.1	Q652K	Pathogenic	0.996
NPHS1	O60500-1.1	Q652L	Pathogenic	0.997
NPHS1	O60500-1.1	Q652M	Pathogenic	0.997
NPHS1	O60500-1.1	Q652N	Pathogenic	0.987
NPHS1	O60500-1.1	Q652P	Pathogenic	0.993
NPHS1	O60500-1.1	Q652R	Pathogenic	0.997
NPHS1	O60500-1.1	Q652S	Pathogenic	0.99
NPHS1	O60500-1.1	Q652T	Pathogenic	0.985
NPHS1	O60500-1.1	Q652V	Pathogenic	0.993
NPHS1	O60500-1.1	Q652W	Pathogenic	0.999
NPHS1	O60500-1.1	Q652Y	Pathogenic	0.995
NPHS1	O60500-1.1	V653A	Pathogenic	0.621
NPHS1	O60500-1.1	V653C	Neutral	0.204
NPHS1	O60500-1.1	V653D	Pathogenic	0.582
NPHS1	O60500-1.1	V653E	Pathogenic	0.574
NPHS1	O60500-1.1	V653F	Neutral	0.355
NPHS1	O60500-1.1	V653G	Pathogenic	0.55
NPHS1	O60500-1.1	V653H	Neutral	0.262
NPHS1	O60500-1.1	V653I	Pathogenic	0.682
NPHS1	O60500-1.1	V653K	Pathogenic	0.808
NPHS1	O60500-1.1	V653L	Neutral	0.453
NPHS1	O60500-1.1	V653M	Neutral	0.292
NPHS1	O60500-1.1	V653N	Neutral	0.491
NPHS1	O60500-1.1	V653P	Neutral	0.188
NPHS1	O60500-1.1	V653Q	Neutral	0.449
NPHS1	O60500-1.1	V653R	Pathogenic	0.797
NPHS1	O60500-1.1	V653S	Pathogenic	0.516
NPHS1	O60500-1.1	V653T	Neutral	0.489
NPHS1	O60500-1.1	V653W	Neutral	0.488
NPHS1	O60500-1.1	V653Y	Neutral	0.284
NPHS1	O60500-1.1	L654A	Neutral	0.056
NPHS1	O60500-1.1	L654C	Neutral	0.014
NPHS1	O60500-1.1	L654D	Neutral	0.048
NPHS1	O60500-1.1	L654E	Neutral	0.039
NPHS1	O60500-1.1	L654F	Neutral	0.004
NPHS1	O60500-1.1	L654G	Neutral	0.043
NPHS1	O60500-1.1	L654H	Neutral	0.01
NPHS1	O60500-1.1	L654I	Neutral	0.007
NPHS1	O60500-1.1	L654K	Neutral	0.085
NPHS1	O60500-1.1	L654M	Neutral	0.013
NPHS1	O60500-1.1	L654N	Neutral	0.05
NPHS1	O60500-1.1	L654P	Neutral	0.008
NPHS1	O60500-1.1	L654Q	Neutral	0.028
NPHS1	O60500-1.1	L654R	Neutral	0.115
NPHS1	O60500-1.1	L654S	Neutral	0.055
NPHS1	O60500-1.1	L654T	Neutral	0.034
NPHS1	O60500-1.1	L654V	Neutral	0.014
NPHS1	O60500-1.1	L654W	Neutral	0.007
NPHS1	O60500-1.1	L654Y	Neutral	0.009
NPHS1	O60500-1.1	V655A	Neutral	0.234
NPHS1	O60500-1.1	V655C	Neutral	0.046
NPHS1	O60500-1.1	V655D	Neutral	0.206
NPHS1	O60500-1.1	V655E	Neutral	0.2
NPHS1	O60500-1.1	V655F	Neutral	0.093
NPHS1	O60500-1.1	V655G	Neutral	0.185
NPHS1	O60500-1.1	V655H	Neutral	0.062
NPHS1	O60500-1.1	V655I	Neutral	0.285
NPHS1	O60500-1.1	V655K	Neutral	0.439
NPHS1	O60500-1.1	V655L	Neutral	0.134
NPHS1	O60500-1.1	V655M	Neutral	0.071
NPHS1	O60500-1.1	V655N	Neutral	0.152
NPHS1	O60500-1.1	V655P	Neutral	0.041
NPHS1	O60500-1.1	V655Q	Neutral	0.132
NPHS1	O60500-1.1	V655R	Neutral	0.422
NPHS1	O60500-1.1	V655S	Neutral	0.166
NPHS1	O60500-1.1	V655T	Neutral	0.151
NPHS1	O60500-1.1	V655W	Neutral	0.151
NPHS1	O60500-1.1	V655Y	Neutral	0.069
NPHS1	O60500-1.1	V656A	Pathogenic	0.974
NPHS1	O60500-1.1	V656C	Pathogenic	0.855
NPHS1	O60500-1.1	V656D	Pathogenic	0.97
NPHS1	O60500-1.1	V656E	Pathogenic	0.969
NPHS1	O60500-1.1	V656F	Pathogenic	0.927
NPHS1	O60500-1.1	V656G	Pathogenic	0.966
NPHS1	O60500-1.1	V656H	Pathogenic	0.891
NPHS1	O60500-1.1	V656I	Pathogenic	0.98
NPHS1	O60500-1.1	V656K	Pathogenic	0.99
NPHS1	O60500-1.1	V656L	Pathogenic	0.95
NPHS1	O60500-1.1	V656M	Pathogenic	0.904
NPHS1	O60500-1.1	V656N	Pathogenic	0.957
NPHS1	O60500-1.1	V656P	Pathogenic	0.842
NPHS1	O60500-1.1	V656Q	Pathogenic	0.949
NPHS1	O60500-1.1	V656R	Pathogenic	0.989
NPHS1	O60500-1.1	V656S	Pathogenic	0.961
NPHS1	O60500-1.1	V656T	Pathogenic	0.956
NPHS1	O60500-1.1	V656W	Pathogenic	0.956
NPHS1	O60500-1.1	V656Y	Pathogenic	0.901
NPHS1	O60500-1.1	T657A	Neutral	0.316
NPHS1	O60500-1.1	T657C	Neutral	0.35
NPHS1	O60500-1.1	T657D	Neutral	0.428
NPHS1	O60500-1.1	T657E	Neutral	0.461
NPHS1	O60500-1.1	T657F	Pathogenic	0.733
NPHS1	O60500-1.1	T657G	Neutral	0.306
NPHS1	O60500-1.1	T657H	Neutral	0.184
NPHS1	O60500-1.1	T657I	Pathogenic	0.763
NPHS1	O60500-1.1	T657K	Pathogenic	0.728
NPHS1	O60500-1.1	T657L	Pathogenic	0.735
NPHS1	O60500-1.1	T657M	Pathogenic	0.579
NPHS1	O60500-1.1	T657N	Neutral	0.471
NPHS1	O60500-1.1	T657P	Neutral	0.249
NPHS1	O60500-1.1	T657Q	Neutral	0.341
NPHS1	O60500-1.1	T657R	Pathogenic	0.788
NPHS1	O60500-1.1	T657S	Neutral	0.461
NPHS1	O60500-1.1	T657V	Pathogenic	0.562
NPHS1	O60500-1.1	T657W	Pathogenic	0.914
NPHS1	O60500-1.1	T657Y	Neutral	0.48
NPHS1	O60500-1.1	A658C	Neutral	0.489
NPHS1	O60500-1.1	A658D	Neutral	0.469
NPHS1	O60500-1.1	A658E	Pathogenic	0.624
NPHS1	O60500-1.1	A658F	Pathogenic	0.82
NPHS1	O60500-1.1	A658G	Neutral	0.357
NPHS1	O60500-1.1	A658H	Neutral	0.304
NPHS1	O60500-1.1	A658I	Pathogenic	0.843
NPHS1	O60500-1.1	A658K	Pathogenic	0.838
NPHS1	O60500-1.1	A658L	Pathogenic	0.821
NPHS1	O60500-1.1	A658M	Pathogenic	0.696
NPHS1	O60500-1.1	A658N	Neutral	0.436
NPHS1	O60500-1.1	A658P	Neutral	0.323
NPHS1	O60500-1.1	A658Q	Pathogenic	0.5
NPHS1	O60500-1.1	A658R	Pathogenic	0.878
NPHS1	O60500-1.1	A658S	Neutral	0.392
NPHS1	O60500-1.1	A658T	Neutral	0.309
NPHS1	O60500-1.1	A658V	Pathogenic	0.68
NPHS1	O60500-1.1	A658W	Pathogenic	0.922
NPHS1	O60500-1.1	A658Y	Pathogenic	0.605
NPHS1	O60500-1.1	V659A	Pathogenic	0.967
NPHS1	O60500-1.1	V659C	Pathogenic	0.819
NPHS1	O60500-1.1	V659D	Pathogenic	0.961
NPHS1	O60500-1.1	V659E	Pathogenic	0.96
NPHS1	O60500-1.1	V659F	Pathogenic	0.907
NPHS1	O60500-1.1	V659G	Pathogenic	0.956
NPHS1	O60500-1.1	V659H	Pathogenic	0.862
NPHS1	O60500-1.1	V659I	Pathogenic	0.974
NPHS1	O60500-1.1	V659K	Pathogenic	0.987
NPHS1	O60500-1.1	V659L	Pathogenic	0.936
NPHS1	O60500-1.1	V659M	Pathogenic	0.879
NPHS1	O60500-1.1	V659N	Pathogenic	0.944
NPHS1	O60500-1.1	V659P	Pathogenic	0.804
NPHS1	O60500-1.1	V659Q	Pathogenic	0.935
NPHS1	O60500-1.1	V659R	Pathogenic	0.986
NPHS1	O60500-1.1	V659S	Pathogenic	0.95
NPHS1	O60500-1.1	V659T	Pathogenic	0.944
NPHS1	O60500-1.1	V659W	Pathogenic	0.944
NPHS1	O60500-1.1	V659Y	Pathogenic	0.875
NPHS1	O60500-1.1	E660A	Pathogenic	0.992
NPHS1	O60500-1.1	E660C	Pathogenic	0.985
NPHS1	O60500-1.1	E660D	Pathogenic	0.986
NPHS1	O60500-1.1	E660F	Pathogenic	0.997
NPHS1	O60500-1.1	E660G	Pathogenic	0.988
NPHS1	O60500-1.1	E660H	Pathogenic	0.985
NPHS1	O60500-1.1	E660I	Pathogenic	0.996
NPHS1	O60500-1.1	E660K	Pathogenic	0.988
NPHS1	O60500-1.1	E660L	Pathogenic	0.996
NPHS1	O60500-1.1	E660M	Pathogenic	0.994
NPHS1	O60500-1.1	E660N	Pathogenic	0.961
NPHS1	O60500-1.1	E660P	Pathogenic	0.993
NPHS1	O60500-1.1	E660Q	Pathogenic	0.988
NPHS1	O60500-1.1	E660R	Pathogenic	0.987
NPHS1	O60500-1.1	E660S	Pathogenic	0.99
NPHS1	O60500-1.1	E660T	Pathogenic	0.984
NPHS1	O60500-1.1	E660V	Pathogenic	0.993
NPHS1	O60500-1.1	E660W	Pathogenic	0.999
NPHS1	O60500-1.1	E660Y	Pathogenic	0.994
NPHS1	O60500-1.1	Q661A	Neutral	0.404
NPHS1	O60500-1.1	Q661C	Neutral	0.347
NPHS1	O60500-1.1	Q661D	Neutral	0.372
NPHS1	O60500-1.1	Q661E	Neutral	0.414
NPHS1	O60500-1.1	Q661F	Pathogenic	0.599
NPHS1	O60500-1.1	Q661G	Neutral	0.31
NPHS1	O60500-1.1	Q661H	Neutral	0.22
NPHS1	O60500-1.1	Q661I	Pathogenic	0.54
NPHS1	O60500-1.1	Q661K	Pathogenic	0.539
NPHS1	O60500-1.1	Q661L	Pathogenic	0.601
NPHS1	O60500-1.1	Q661M	Pathogenic	0.625
NPHS1	O60500-1.1	Q661N	Neutral	0.29
NPHS1	O60500-1.1	Q661P	Neutral	0.42
NPHS1	O60500-1.1	Q661R	Pathogenic	0.619
NPHS1	O60500-1.1	Q661S	Neutral	0.344
NPHS1	O60500-1.1	Q661T	Neutral	0.253
NPHS1	O60500-1.1	Q661V	Neutral	0.417
NPHS1	O60500-1.1	Q661W	Pathogenic	0.896
NPHS1	O60500-1.1	Q661Y	Pathogenic	0.527
NPHS1	O60500-1.1	G662A	Pathogenic	0.714
NPHS1	O60500-1.1	G662C	Pathogenic	0.763
NPHS1	O60500-1.1	G662D	Pathogenic	0.854
NPHS1	O60500-1.1	G662E	Pathogenic	0.832
NPHS1	O60500-1.1	G662F	Pathogenic	0.971
NPHS1	O60500-1.1	G662H	Pathogenic	0.743
NPHS1	O60500-1.1	G662I	Pathogenic	0.947
NPHS1	O60500-1.1	G662K	Pathogenic	0.939
NPHS1	O60500-1.1	G662L	Pathogenic	0.939
NPHS1	O60500-1.1	G662M	Pathogenic	0.92
NPHS1	O60500-1.1	G662N	Pathogenic	0.885
NPHS1	O60500-1.1	G662P	Pathogenic	0.781
NPHS1	O60500-1.1	G662Q	Pathogenic	0.749
NPHS1	O60500-1.1	G662R	Pathogenic	0.955
NPHS1	O60500-1.1	G662S	Pathogenic	0.658
NPHS1	O60500-1.1	G662T	Pathogenic	0.658
NPHS1	O60500-1.1	G662V	Pathogenic	0.877
NPHS1	O60500-1.1	G662W	Pathogenic	0.995
NPHS1	O60500-1.1	G662Y	Pathogenic	0.92
NPHS1	O60500-1.1	E663A	Neutral	0.241
NPHS1	O60500-1.1	E663C	Neutral	0.143
NPHS1	O60500-1.1	E663D	Neutral	0.151
NPHS1	O60500-1.1	E663F	Neutral	0.47
NPHS1	O60500-1.1	E663G	Neutral	0.174
NPHS1	O60500-1.1	E663H	Neutral	0.143
NPHS1	O60500-1.1	E663I	Neutral	0.411
NPHS1	O60500-1.1	E663K	Neutral	0.167
NPHS1	O60500-1.1	E663L	Neutral	0.375
NPHS1	O60500-1.1	E663M	Neutral	0.308
NPHS1	O60500-1.1	E663N	Neutral	0.058
NPHS1	O60500-1.1	E663P	Neutral	0.254
NPHS1	O60500-1.1	E663Q	Neutral	0.167
NPHS1	O60500-1.1	E663R	Neutral	0.157
NPHS1	O60500-1.1	E663S	Neutral	0.197
NPHS1	O60500-1.1	E663T	Neutral	0.137
NPHS1	O60500-1.1	E663V	Neutral	0.251
NPHS1	O60500-1.1	E663W	Pathogenic	0.773
NPHS1	O60500-1.1	E663Y	Neutral	0.307
NPHS1	O60500-1.1	A664C	Pathogenic	0.9
NPHS1	O60500-1.1	A664D	Pathogenic	0.892
NPHS1	O60500-1.1	A664E	Pathogenic	0.939
NPHS1	O60500-1.1	A664F	Pathogenic	0.977
NPHS1	O60500-1.1	A664G	Pathogenic	0.839
NPHS1	O60500-1.1	A664H	Pathogenic	0.804
NPHS1	O60500-1.1	A664I	Pathogenic	0.98
NPHS1	O60500-1.1	A664K	Pathogenic	0.98
NPHS1	O60500-1.1	A664L	Pathogenic	0.977
NPHS1	O60500-1.1	A664M	Pathogenic	0.955
NPHS1	O60500-1.1	A664N	Pathogenic	0.879
NPHS1	O60500-1.1	A664P	Pathogenic	0.817
NPHS1	O60500-1.1	A664Q	Pathogenic	0.904
NPHS1	O60500-1.1	A664R	Pathogenic	0.985
NPHS1	O60500-1.1	A664S	Pathogenic	0.858
NPHS1	O60500-1.1	A664T	Pathogenic	0.807
NPHS1	O60500-1.1	A664V	Pathogenic	0.952
NPHS1	O60500-1.1	A664W	Pathogenic	0.991
NPHS1	O60500-1.1	A664Y	Pathogenic	0.935
NPHS1	O60500-1.1	L665A	Pathogenic	0.871
NPHS1	O60500-1.1	L665C	Pathogenic	0.613
NPHS1	O60500-1.1	L665D	Pathogenic	0.852
NPHS1	O60500-1.1	L665E	Pathogenic	0.822
NPHS1	O60500-1.1	L665F	Neutral	0.328
NPHS1	O60500-1.1	L665G	Pathogenic	0.835
NPHS1	O60500-1.1	L665H	Pathogenic	0.542
NPHS1	O60500-1.1	L665I	Neutral	0.461
NPHS1	O60500-1.1	L665K	Pathogenic	0.914
NPHS1	O60500-1.1	L665M	Pathogenic	0.596
NPHS1	O60500-1.1	L665N	Pathogenic	0.856
NPHS1	O60500-1.1	L665P	Neutral	0.49
NPHS1	O60500-1.1	L665Q	Pathogenic	0.766
NPHS1	O60500-1.1	L665R	Pathogenic	0.936
NPHS1	O60500-1.1	L665S	Pathogenic	0.868
NPHS1	O60500-1.1	L665T	Pathogenic	0.798
NPHS1	O60500-1.1	L665V	Pathogenic	0.613
NPHS1	O60500-1.1	L665W	Neutral	0.458
NPHS1	O60500-1.1	L665Y	Neutral	0.499
NPHS1	O60500-1.1	L666A	Pathogenic	0.92
NPHS1	O60500-1.1	L666C	Pathogenic	0.729
NPHS1	O60500-1.1	L666D	Pathogenic	0.907
NPHS1	O60500-1.1	L666E	Pathogenic	0.887
NPHS1	O60500-1.1	L666F	Neutral	0.453
NPHS1	O60500-1.1	L666G	Pathogenic	0.896
NPHS1	O60500-1.1	L666H	Pathogenic	0.668
NPHS1	O60500-1.1	L666I	Pathogenic	0.592
NPHS1	O60500-1.1	L666K	Pathogenic	0.947
NPHS1	O60500-1.1	L666M	Pathogenic	0.715
NPHS1	O60500-1.1	L666N	Pathogenic	0.91
NPHS1	O60500-1.1	L666P	Pathogenic	0.619
NPHS1	O60500-1.1	L666Q	Pathogenic	0.848
NPHS1	O60500-1.1	L666R	Pathogenic	0.961
NPHS1	O60500-1.1	L666S	Pathogenic	0.918
NPHS1	O60500-1.1	L666T	Pathogenic	0.87
NPHS1	O60500-1.1	L666V	Pathogenic	0.729
NPHS1	O60500-1.1	L666W	Pathogenic	0.589
NPHS1	O60500-1.1	L666Y	Pathogenic	0.628
NPHS1	O60500-1.1	P667A	Pathogenic	0.971
NPHS1	O60500-1.1	P667C	Pathogenic	0.886
NPHS1	O60500-1.1	P667D	Pathogenic	0.99
NPHS1	O60500-1.1	P667E	Pathogenic	0.992
NPHS1	O60500-1.1	P667F	Pathogenic	0.979
NPHS1	O60500-1.1	P667G	Pathogenic	0.983
NPHS1	O60500-1.1	P667H	Pathogenic	0.971
NPHS1	O60500-1.1	P667I	Pathogenic	0.982
NPHS1	O60500-1.1	P667K	Pathogenic	0.997
NPHS1	O60500-1.1	P667L	Pathogenic	0.979
NPHS1	O60500-1.1	P667M	Pathogenic	0.972
NPHS1	O60500-1.1	P667N	Pathogenic	0.983
NPHS1	O60500-1.1	P667Q	Pathogenic	0.987
NPHS1	O60500-1.1	P667R	Pathogenic	0.997
NPHS1	O60500-1.1	P667S	Pathogenic	0.98
NPHS1	O60500-1.1	P667T	Pathogenic	0.958
NPHS1	O60500-1.1	P667V	Pathogenic	0.955
NPHS1	O60500-1.1	P667W	Pathogenic	0.994
NPHS1	O60500-1.1	P667Y	Pathogenic	0.958
NPHS1	O60500-1.1	V668A	Pathogenic	0.788
NPHS1	O60500-1.1	V668C	Neutral	0.368
NPHS1	O60500-1.1	V668D	Pathogenic	0.759
NPHS1	O60500-1.1	V668E	Pathogenic	0.753
NPHS1	O60500-1.1	V668F	Pathogenic	0.555
NPHS1	O60500-1.1	V668G	Pathogenic	0.735
NPHS1	O60500-1.1	V668H	Neutral	0.446
NPHS1	O60500-1.1	V668I	Pathogenic	0.829
NPHS1	O60500-1.1	V668K	Pathogenic	0.905
NPHS1	O60500-1.1	V668L	Pathogenic	0.652
NPHS1	O60500-1.1	V668M	Neutral	0.482
NPHS1	O60500-1.1	V668N	Pathogenic	0.685
NPHS1	O60500-1.1	V668P	Neutral	0.344
NPHS1	O60500-1.1	V668Q	Pathogenic	0.648
NPHS1	O60500-1.1	V668R	Pathogenic	0.899
NPHS1	O60500-1.1	V668S	Pathogenic	0.707
NPHS1	O60500-1.1	V668T	Pathogenic	0.684
NPHS1	O60500-1.1	V668W	Pathogenic	0.683
NPHS1	O60500-1.1	V668Y	Neutral	0.473
NPHS1	O60500-1.1	S669A	Neutral	0.042
NPHS1	O60500-1.1	S669C	Neutral	0.059
NPHS1	O60500-1.1	S669D	Neutral	0.065
NPHS1	O60500-1.1	S669E	Neutral	0.08
NPHS1	O60500-1.1	S669F	Neutral	0.309
NPHS1	O60500-1.1	S669G	Neutral	0.028
NPHS1	O60500-1.1	S669H	Neutral	0.036
NPHS1	O60500-1.1	S669I	Neutral	0.26
NPHS1	O60500-1.1	S669K	Neutral	0.213
NPHS1	O60500-1.1	S669L	Neutral	0.232
NPHS1	O60500-1.1	S669M	Neutral	0.183
NPHS1	O60500-1.1	S669N	Neutral	0.083
NPHS1	O60500-1.1	S669P	Neutral	0.045
NPHS1	O60500-1.1	S669Q	Neutral	0.05
NPHS1	O60500-1.1	S669R	Neutral	0.202
NPHS1	O60500-1.1	S669T	Neutral	0.053
NPHS1	O60500-1.1	S669V	Neutral	0.086
NPHS1	O60500-1.1	S669W	Pathogenic	0.536
NPHS1	O60500-1.1	S669Y	Neutral	0.13
NPHS1	O60500-1.1	V670A	Pathogenic	0.982
NPHS1	O60500-1.1	V670C	Pathogenic	0.893
NPHS1	O60500-1.1	V670D	Pathogenic	0.978
NPHS1	O60500-1.1	V670E	Pathogenic	0.978
NPHS1	O60500-1.1	V670F	Pathogenic	0.947
NPHS1	O60500-1.1	V670G	Pathogenic	0.975
NPHS1	O60500-1.1	V670H	Pathogenic	0.92
NPHS1	O60500-1.1	V670I	Pathogenic	0.986
NPHS1	O60500-1.1	V670K	Pathogenic	0.993
NPHS1	O60500-1.1	V670L	Pathogenic	0.964
NPHS1	O60500-1.1	V670M	Pathogenic	0.93
NPHS1	O60500-1.1	V670N	Pathogenic	0.969
NPHS1	O60500-1.1	V670P	Pathogenic	0.883
NPHS1	O60500-1.1	V670Q	Pathogenic	0.964
NPHS1	O60500-1.1	V670R	Pathogenic	0.992
NPHS1	O60500-1.1	V670S	Pathogenic	0.972
NPHS1	O60500-1.1	V670T	Pathogenic	0.969
NPHS1	O60500-1.1	V670W	Pathogenic	0.969
NPHS1	O60500-1.1	V670Y	Pathogenic	0.928
NPHS1	O60500-1.1	S671A	Pathogenic	0.923
NPHS1	O60500-1.1	S671C	Pathogenic	0.946
NPHS1	O60500-1.1	S671D	Pathogenic	0.95
NPHS1	O60500-1.1	S671E	Pathogenic	0.96
NPHS1	O60500-1.1	S671F	Pathogenic	0.992
NPHS1	O60500-1.1	S671G	Pathogenic	0.889
NPHS1	O60500-1.1	S671H	Pathogenic	0.913
NPHS1	O60500-1.1	S671I	Pathogenic	0.99
NPHS1	O60500-1.1	S671K	Pathogenic	0.987
NPHS1	O60500-1.1	S671L	Pathogenic	0.988
NPHS1	O60500-1.1	S671M	Pathogenic	0.984
NPHS1	O60500-1.1	S671N	Pathogenic	0.961
NPHS1	O60500-1.1	S671P	Pathogenic	0.928
NPHS1	O60500-1.1	S671Q	Pathogenic	0.936
NPHS1	O60500-1.1	S671R	Pathogenic	0.986
NPHS1	O60500-1.1	S671T	Pathogenic	0.939
NPHS1	O60500-1.1	S671V	Pathogenic	0.963
NPHS1	O60500-1.1	S671W	Pathogenic	0.997
NPHS1	O60500-1.1	S671Y	Pathogenic	0.976
NPHS1	O60500-1.1	A672C	Pathogenic	0.943
NPHS1	O60500-1.1	A672D	Pathogenic	0.938
NPHS1	O60500-1.1	A672E	Pathogenic	0.966
NPHS1	O60500-1.1	A672F	Pathogenic	0.987
NPHS1	O60500-1.1	A672G	Pathogenic	0.905
NPHS1	O60500-1.1	A672H	Pathogenic	0.883
NPHS1	O60500-1.1	A672I	Pathogenic	0.989
NPHS1	O60500-1.1	A672K	Pathogenic	0.989
NPHS1	O60500-1.1	A672L	Pathogenic	0.987
NPHS1	O60500-1.1	A672M	Pathogenic	0.975
NPHS1	O60500-1.1	A672N	Pathogenic	0.93
NPHS1	O60500-1.1	A672P	Pathogenic	0.891
NPHS1	O60500-1.1	A672Q	Pathogenic	0.945
NPHS1	O60500-1.1	A672R	Pathogenic	0.992
NPHS1	O60500-1.1	A672S	Pathogenic	0.917
NPHS1	O60500-1.1	A672T	Pathogenic	0.885
NPHS1	O60500-1.1	A672V	Pathogenic	0.973
NPHS1	O60500-1.1	A672W	Pathogenic	0.995
NPHS1	O60500-1.1	A672Y	Pathogenic	0.963
NPHS1	O60500-1.1	N673A	Pathogenic	0.979
NPHS1	O60500-1.1	N673C	Pathogenic	0.982
NPHS1	O60500-1.1	N673D	Pathogenic	0.967
NPHS1	O60500-1.1	N673E	Pathogenic	0.951
NPHS1	O60500-1.1	N673F	Pathogenic	0.997
NPHS1	O60500-1.1	N673G	Pathogenic	0.99
NPHS1	O60500-1.1	N673H	Pathogenic	0.99
NPHS1	O60500-1.1	N673I	Pathogenic	0.997
NPHS1	O60500-1.1	N673K	Pathogenic	0.984
NPHS1	O60500-1.1	N673L	Pathogenic	0.996
NPHS1	O60500-1.1	N673M	Pathogenic	0.995
NPHS1	O60500-1.1	N673P	Pathogenic	0.981
NPHS1	O60500-1.1	N673Q	Pathogenic	0.974
NPHS1	O60500-1.1	N673R	Pathogenic	0.988
NPHS1	O60500-1.1	N673S	Pathogenic	0.988
NPHS1	O60500-1.1	N673T	Pathogenic	0.981
NPHS1	O60500-1.1	N673V	Pathogenic	0.987
NPHS1	O60500-1.1	N673W	Pathogenic	0.999
NPHS1	O60500-1.1	N673Y	Pathogenic	0.995
NPHS1	O60500-1.1	P674A	Pathogenic	0.982
NPHS1	O60500-1.1	P674C	Pathogenic	0.924
NPHS1	O60500-1.1	P674D	Pathogenic	0.994
NPHS1	O60500-1.1	P674E	Pathogenic	0.995
NPHS1	O60500-1.1	P674F	Pathogenic	0.986
NPHS1	O60500-1.1	P674G	Pathogenic	0.989
NPHS1	O60500-1.1	P674H	Pathogenic	0.981
NPHS1	O60500-1.1	P674I	Pathogenic	0.988
NPHS1	O60500-1.1	P674K	Pathogenic	0.998
NPHS1	O60500-1.1	P674L	Pathogenic	0.986
NPHS1	O60500-1.1	P674M	Pathogenic	0.982
NPHS1	O60500-1.1	P674N	Pathogenic	0.989
NPHS1	O60500-1.1	P674Q	Pathogenic	0.992
NPHS1	O60500-1.1	P674R	Pathogenic	0.998
NPHS1	O60500-1.1	P674S	Pathogenic	0.987
NPHS1	O60500-1.1	P674T	Pathogenic	0.973
NPHS1	O60500-1.1	P674V	Pathogenic	0.971
NPHS1	O60500-1.1	P674W	Pathogenic	0.996
NPHS1	O60500-1.1	P674Y	Pathogenic	0.973
NPHS1	O60500-1.1	A675C	Neutral	0.23
NPHS1	O60500-1.1	A675D	Neutral	0.216
NPHS1	O60500-1.1	A675E	Neutral	0.34
NPHS1	O60500-1.1	A675F	Pathogenic	0.586
NPHS1	O60500-1.1	A675G	Neutral	0.147
NPHS1	O60500-1.1	A675H	Neutral	0.12
NPHS1	O60500-1.1	A675I	Pathogenic	0.625
NPHS1	O60500-1.1	A675K	Pathogenic	0.617
NPHS1	O60500-1.1	A675L	Pathogenic	0.588
NPHS1	O60500-1.1	A675M	Neutral	0.415
NPHS1	O60500-1.1	A675N	Neutral	0.194
NPHS1	O60500-1.1	A675P	Neutral	0.129
NPHS1	O60500-1.1	A675Q	Neutral	0.237
NPHS1	O60500-1.1	A675R	Pathogenic	0.691
NPHS1	O60500-1.1	A675S	Neutral	0.167
NPHS1	O60500-1.1	A675T	Neutral	0.122
NPHS1	O60500-1.1	A675V	Neutral	0.398
NPHS1	O60500-1.1	A675W	Pathogenic	0.785
NPHS1	O60500-1.1	A675Y	Neutral	0.322
NPHS1	O60500-1.1	P676A	Neutral	0.239
NPHS1	O60500-1.1	P676C	Neutral	0.068
NPHS1	O60500-1.1	P676D	Neutral	0.482
NPHS1	O60500-1.1	P676E	Pathogenic	0.539
NPHS1	O60500-1.1	P676F	Neutral	0.299
NPHS1	O60500-1.1	P676G	Neutral	0.343
NPHS1	O60500-1.1	P676H	Neutral	0.236
NPHS1	O60500-1.1	P676I	Neutral	0.333
NPHS1	O60500-1.1	P676K	Pathogenic	0.785
NPHS1	O60500-1.1	P676L	Neutral	0.3
NPHS1	O60500-1.1	P676M	Neutral	0.242
NPHS1	O60500-1.1	P676N	Neutral	0.353
NPHS1	O60500-1.1	P676Q	Neutral	0.414
NPHS1	O60500-1.1	P676R	Pathogenic	0.773
NPHS1	O60500-1.1	P676S	Neutral	0.313
NPHS1	O60500-1.1	P676T	Neutral	0.175
NPHS1	O60500-1.1	P676V	Neutral	0.166
NPHS1	O60500-1.1	P676W	Pathogenic	0.621
NPHS1	O60500-1.1	P676Y	Neutral	0.176
NPHS1	O60500-1.1	E677A	Neutral	0.269
NPHS1	O60500-1.1	E677C	Neutral	0.162
NPHS1	O60500-1.1	E677D	Neutral	0.171
NPHS1	O60500-1.1	E677F	Pathogenic	0.507
NPHS1	O60500-1.1	E677G	Neutral	0.197
NPHS1	O60500-1.1	E677H	Neutral	0.162
NPHS1	O60500-1.1	E677I	Neutral	0.448
NPHS1	O60500-1.1	E677K	Neutral	0.188
NPHS1	O60500-1.1	E677L	Neutral	0.41
NPHS1	O60500-1.1	E677M	Neutral	0.34
NPHS1	O60500-1.1	E677N	Neutral	0.067
NPHS1	O60500-1.1	E677P	Neutral	0.283
NPHS1	O60500-1.1	E677Q	Neutral	0.189
NPHS1	O60500-1.1	E677R	Neutral	0.178
NPHS1	O60500-1.1	E677S	Neutral	0.222
NPHS1	O60500-1.1	E677T	Neutral	0.156
NPHS1	O60500-1.1	E677V	Neutral	0.28
NPHS1	O60500-1.1	E677W	Pathogenic	0.798
NPHS1	O60500-1.1	E677Y	Neutral	0.34
NPHS1	O60500-1.1	A678C	Neutral	0.22
NPHS1	O60500-1.1	A678D	Neutral	0.207
NPHS1	O60500-1.1	A678E	Neutral	0.328
NPHS1	O60500-1.1	A678F	Pathogenic	0.573
NPHS1	O60500-1.1	A678G	Neutral	0.141
NPHS1	O60500-1.1	A678H	Neutral	0.114
NPHS1	O60500-1.1	A678I	Pathogenic	0.612
NPHS1	O60500-1.1	A678K	Pathogenic	0.604
NPHS1	O60500-1.1	A678L	Pathogenic	0.576
NPHS1	O60500-1.1	A678M	Neutral	0.403
NPHS1	O60500-1.1	A678N	Neutral	0.186
NPHS1	O60500-1.1	A678P	Neutral	0.123
NPHS1	O60500-1.1	A678Q	Neutral	0.228
NPHS1	O60500-1.1	A678R	Pathogenic	0.68
NPHS1	O60500-1.1	A678S	Neutral	0.16
NPHS1	O60500-1.1	A678T	Neutral	0.117
NPHS1	O60500-1.1	A678V	Neutral	0.386
NPHS1	O60500-1.1	A678W	Pathogenic	0.776
NPHS1	O60500-1.1	A678Y	Neutral	0.311
NPHS1	O60500-1.1	F679A	Pathogenic	0.943
NPHS1	O60500-1.1	F679C	Pathogenic	0.795
NPHS1	O60500-1.1	F679D	Pathogenic	0.969
NPHS1	O60500-1.1	F679E	Pathogenic	0.944
NPHS1	O60500-1.1	F679G	Pathogenic	0.965
NPHS1	O60500-1.1	F679H	Pathogenic	0.906
NPHS1	O60500-1.1	F679I	Pathogenic	0.52
NPHS1	O60500-1.1	F679K	Pathogenic	0.939
NPHS1	O60500-1.1	F679L	Pathogenic	0.547
NPHS1	O60500-1.1	F679M	Pathogenic	0.708
NPHS1	O60500-1.1	F679N	Pathogenic	0.956
NPHS1	O60500-1.1	F679P	Pathogenic	0.702
NPHS1	O60500-1.1	F679Q	Pathogenic	0.889
NPHS1	O60500-1.1	F679R	Pathogenic	0.955
NPHS1	O60500-1.1	F679S	Pathogenic	0.96
NPHS1	O60500-1.1	F679T	Pathogenic	0.906
NPHS1	O60500-1.1	F679V	Pathogenic	0.723
NPHS1	O60500-1.1	F679W	Pathogenic	0.824
NPHS1	O60500-1.1	F679Y	Pathogenic	0.915
NPHS1	O60500-1.1	N680A	Neutral	0.033
NPHS1	O60500-1.1	N680C	Neutral	0.038
NPHS1	O60500-1.1	N680D	Neutral	0.021
NPHS1	O60500-1.1	N680E	Neutral	0.014
NPHS1	O60500-1.1	N680F	Neutral	0.205
NPHS1	O60500-1.1	N680G	Neutral	0.069
NPHS1	O60500-1.1	N680H	Neutral	0.068
NPHS1	O60500-1.1	N680I	Neutral	0.169
NPHS1	O60500-1.1	N680K	Neutral	0.042
NPHS1	O60500-1.1	N680L	Neutral	0.149
NPHS1	O60500-1.1	N680M	Neutral	0.115
NPHS1	O60500-1.1	N680P	Neutral	0.035
NPHS1	O60500-1.1	N680Q	Neutral	0.026
NPHS1	O60500-1.1	N680R	Neutral	0.057
NPHS1	O60500-1.1	N680S	Neutral	0.055
NPHS1	O60500-1.1	N680T	Neutral	0.036
NPHS1	O60500-1.1	N680V	Neutral	0.052
NPHS1	O60500-1.1	N680W	Neutral	0.401
NPHS1	O60500-1.1	N680Y	Neutral	0.115
NPHS1	O60500-1.1	W681A	Pathogenic	1.0
NPHS1	O60500-1.1	W681C	Pathogenic	1.0
NPHS1	O60500-1.1	W681D	Pathogenic	1.0
NPHS1	O60500-1.1	W681E	Pathogenic	1.0
NPHS1	O60500-1.1	W681F	Pathogenic	0.999
NPHS1	O60500-1.1	W681G	Pathogenic	1.0
NPHS1	O60500-1.1	W681H	Pathogenic	1.0
NPHS1	O60500-1.1	W681I	Pathogenic	0.995
NPHS1	O60500-1.1	W681K	Pathogenic	1.0
NPHS1	O60500-1.1	W681L	Pathogenic	0.997
NPHS1	O60500-1.1	W681M	Pathogenic	0.999
NPHS1	O60500-1.1	W681N	Pathogenic	1.0
NPHS1	O60500-1.1	W681P	Pathogenic	0.999
NPHS1	O60500-1.1	W681Q	Pathogenic	1.0
NPHS1	O60500-1.1	W681R	Pathogenic	1.0
NPHS1	O60500-1.1	W681S	Pathogenic	1.0
NPHS1	O60500-1.1	W681T	Pathogenic	1.0
NPHS1	O60500-1.1	W681V	Pathogenic	0.999
NPHS1	O60500-1.1	W681Y	Pathogenic	1.0
NPHS1	O60500-1.1	T682A	Neutral	0.415
NPHS1	O60500-1.1	T682C	Neutral	0.453
NPHS1	O60500-1.1	T682D	Pathogenic	0.535
NPHS1	O60500-1.1	T682E	Pathogenic	0.568
NPHS1	O60500-1.1	T682F	Pathogenic	0.808
NPHS1	O60500-1.1	T682G	Neutral	0.404
NPHS1	O60500-1.1	T682H	Neutral	0.258
NPHS1	O60500-1.1	T682I	Pathogenic	0.832
NPHS1	O60500-1.1	T682K	Pathogenic	0.804
NPHS1	O60500-1.1	T682L	Pathogenic	0.809
NPHS1	O60500-1.1	T682M	Pathogenic	0.679
NPHS1	O60500-1.1	T682N	Pathogenic	0.577
NPHS1	O60500-1.1	T682P	Neutral	0.337
NPHS1	O60500-1.1	T682Q	Neutral	0.443
NPHS1	O60500-1.1	T682R	Pathogenic	0.851
NPHS1	O60500-1.1	T682S	Pathogenic	0.568
NPHS1	O60500-1.1	T682V	Pathogenic	0.663
NPHS1	O60500-1.1	T682W	Pathogenic	0.942
NPHS1	O60500-1.1	T682Y	Pathogenic	0.586
NPHS1	O60500-1.1	F683A	Pathogenic	0.989
NPHS1	O60500-1.1	F683C	Pathogenic	0.956
NPHS1	O60500-1.1	F683D	Pathogenic	0.994
NPHS1	O60500-1.1	F683E	Pathogenic	0.989
NPHS1	O60500-1.1	F683G	Pathogenic	0.994
NPHS1	O60500-1.1	F683H	Pathogenic	0.982
NPHS1	O60500-1.1	F683I	Pathogenic	0.858
NPHS1	O60500-1.1	F683K	Pathogenic	0.988
NPHS1	O60500-1.1	F683L	Pathogenic	0.87
NPHS1	O60500-1.1	F683M	Pathogenic	0.931
NPHS1	O60500-1.1	F683N	Pathogenic	0.992
NPHS1	O60500-1.1	F683P	Pathogenic	0.929
NPHS1	O60500-1.1	F683Q	Pathogenic	0.978
NPHS1	O60500-1.1	F683R	Pathogenic	0.992
NPHS1	O60500-1.1	F683S	Pathogenic	0.993
NPHS1	O60500-1.1	F683T	Pathogenic	0.982
NPHS1	O60500-1.1	F683V	Pathogenic	0.935
NPHS1	O60500-1.1	F683W	Pathogenic	0.963
NPHS1	O60500-1.1	F683Y	Pathogenic	0.983
NPHS1	O60500-1.1	R684A	Pathogenic	0.926
NPHS1	O60500-1.1	R684C	Pathogenic	0.908
NPHS1	O60500-1.1	R684D	Neutral	0.49
NPHS1	O60500-1.1	R684E	Pathogenic	0.629
NPHS1	O60500-1.1	R684F	Pathogenic	0.911
NPHS1	O60500-1.1	R684G	Pathogenic	0.893
NPHS1	O60500-1.1	R684H	Pathogenic	0.812
NPHS1	O60500-1.1	R684I	Pathogenic	0.931
NPHS1	O60500-1.1	R684K	Pathogenic	0.548
NPHS1	O60500-1.1	R684L	Pathogenic	0.946
NPHS1	O60500-1.1	R684M	Pathogenic	0.928
NPHS1	O60500-1.1	R684N	Pathogenic	0.709
NPHS1	O60500-1.1	R684P	Pathogenic	0.9
NPHS1	O60500-1.1	R684Q	Pathogenic	0.807
NPHS1	O60500-1.1	R684S	Pathogenic	0.867
NPHS1	O60500-1.1	R684T	Pathogenic	0.863
NPHS1	O60500-1.1	R684V	Pathogenic	0.899
NPHS1	O60500-1.1	R684W	Pathogenic	0.955
NPHS1	O60500-1.1	R684Y	Pathogenic	0.795
NPHS1	O60500-1.1	G685A	Pathogenic	0.882
NPHS1	O60500-1.1	G685C	Pathogenic	0.906
NPHS1	O60500-1.1	G685D	Pathogenic	0.946
NPHS1	O60500-1.1	G685E	Pathogenic	0.937
NPHS1	O60500-1.1	G685F	Pathogenic	0.99
NPHS1	O60500-1.1	G685H	Pathogenic	0.896
NPHS1	O60500-1.1	G685I	Pathogenic	0.982
NPHS1	O60500-1.1	G685K	Pathogenic	0.979
NPHS1	O60500-1.1	G685L	Pathogenic	0.979
NPHS1	O60500-1.1	G685M	Pathogenic	0.972
NPHS1	O60500-1.1	G685N	Pathogenic	0.958
NPHS1	O60500-1.1	G685P	Pathogenic	0.914
NPHS1	O60500-1.1	G685Q	Pathogenic	0.9
NPHS1	O60500-1.1	G685R	Pathogenic	0.985
NPHS1	O60500-1.1	G685S	Pathogenic	0.852
NPHS1	O60500-1.1	G685T	Pathogenic	0.852
NPHS1	O60500-1.1	G685V	Pathogenic	0.955
NPHS1	O60500-1.1	G685W	Pathogenic	0.998
NPHS1	O60500-1.1	G685Y	Pathogenic	0.972
NPHS1	O60500-1.1	Y686A	Pathogenic	0.852
NPHS1	O60500-1.1	Y686C	Pathogenic	0.591
NPHS1	O60500-1.1	Y686D	Pathogenic	0.916
NPHS1	O60500-1.1	Y686E	Pathogenic	0.897
NPHS1	O60500-1.1	Y686F	Pathogenic	0.917
NPHS1	O60500-1.1	Y686G	Pathogenic	0.906
NPHS1	O60500-1.1	Y686H	Pathogenic	0.918
NPHS1	O60500-1.1	Y686I	Pathogenic	0.749
NPHS1	O60500-1.1	Y686K	Pathogenic	0.889
NPHS1	O60500-1.1	Y686L	Pathogenic	0.719
NPHS1	O60500-1.1	Y686M	Pathogenic	0.56
NPHS1	O60500-1.1	Y686N	Pathogenic	0.918
NPHS1	O60500-1.1	Y686P	Pathogenic	0.55
NPHS1	O60500-1.1	Y686Q	Pathogenic	0.862
NPHS1	O60500-1.1	Y686R	Pathogenic	0.893
NPHS1	O60500-1.1	Y686S	Pathogenic	0.893
NPHS1	O60500-1.1	Y686T	Pathogenic	0.771
NPHS1	O60500-1.1	Y686V	Pathogenic	0.661
NPHS1	O60500-1.1	Y686W	Pathogenic	0.956
NPHS1	O60500-1.1	R687A	Pathogenic	0.68
NPHS1	O60500-1.1	R687C	Pathogenic	0.625
NPHS1	O60500-1.1	R687D	Neutral	0.14
NPHS1	O60500-1.1	R687E	Neutral	0.224
NPHS1	O60500-1.1	R687F	Pathogenic	0.635
NPHS1	O60500-1.1	R687G	Pathogenic	0.586
NPHS1	O60500-1.1	R687H	Neutral	0.423
NPHS1	O60500-1.1	R687I	Pathogenic	0.697
NPHS1	O60500-1.1	R687K	Neutral	0.17
NPHS1	O60500-1.1	R687L	Pathogenic	0.747
NPHS1	O60500-1.1	R687M	Pathogenic	0.686
NPHS1	O60500-1.1	R687N	Neutral	0.293
NPHS1	O60500-1.1	R687P	Pathogenic	0.604
NPHS1	O60500-1.1	R687Q	Neutral	0.416
NPHS1	O60500-1.1	R687S	Pathogenic	0.525
NPHS1	O60500-1.1	R687T	Pathogenic	0.516
NPHS1	O60500-1.1	R687V	Pathogenic	0.601
NPHS1	O60500-1.1	R687W	Pathogenic	0.784
NPHS1	O60500-1.1	R687Y	Neutral	0.396
NPHS1	O60500-1.1	L688A	Pathogenic	0.994
NPHS1	O60500-1.1	L688C	Pathogenic	0.976
NPHS1	O60500-1.1	L688D	Pathogenic	0.993
NPHS1	O60500-1.1	L688E	Pathogenic	0.992
NPHS1	O60500-1.1	L688F	Pathogenic	0.927
NPHS1	O60500-1.1	L688G	Pathogenic	0.992
NPHS1	O60500-1.1	L688H	Pathogenic	0.969
NPHS1	O60500-1.1	L688I	Pathogenic	0.957
NPHS1	O60500-1.1	L688K	Pathogenic	0.996
NPHS1	O60500-1.1	L688M	Pathogenic	0.975
NPHS1	O60500-1.1	L688N	Pathogenic	0.994
NPHS1	O60500-1.1	L688P	Pathogenic	0.961
NPHS1	O60500-1.1	L688Q	Pathogenic	0.988
NPHS1	O60500-1.1	L688R	Pathogenic	0.997
NPHS1	O60500-1.1	L688S	Pathogenic	0.994
NPHS1	O60500-1.1	L688T	Pathogenic	0.99
NPHS1	O60500-1.1	L688V	Pathogenic	0.976
NPHS1	O60500-1.1	L688W	Pathogenic	0.956
NPHS1	O60500-1.1	L688Y	Pathogenic	0.963
NPHS1	O60500-1.1	S689A	Neutral	0.101
NPHS1	O60500-1.1	S689C	Neutral	0.14
NPHS1	O60500-1.1	S689D	Neutral	0.152
NPHS1	O60500-1.1	S689E	Neutral	0.184
NPHS1	O60500-1.1	S689F	Pathogenic	0.537
NPHS1	O60500-1.1	S689G	Neutral	0.07
NPHS1	O60500-1.1	S689H	Neutral	0.089
NPHS1	O60500-1.1	S689I	Neutral	0.477
NPHS1	O60500-1.1	S689K	Neutral	0.413
NPHS1	O60500-1.1	S689L	Neutral	0.439
NPHS1	O60500-1.1	S689M	Neutral	0.368
NPHS1	O60500-1.1	S689N	Neutral	0.19
NPHS1	O60500-1.1	S689P	Neutral	0.108
NPHS1	O60500-1.1	S689Q	Neutral	0.12
NPHS1	O60500-1.1	S689R	Neutral	0.396
NPHS1	O60500-1.1	S689T	Neutral	0.127
NPHS1	O60500-1.1	S689V	Neutral	0.196
NPHS1	O60500-1.1	S689W	Pathogenic	0.749
NPHS1	O60500-1.1	S689Y	Neutral	0.28
NPHS1	O60500-1.1	P690A	Neutral	0.498
NPHS1	O60500-1.1	P690C	Neutral	0.186
NPHS1	O60500-1.1	P690D	Pathogenic	0.745
NPHS1	O60500-1.1	P690E	Pathogenic	0.786
NPHS1	O60500-1.1	P690F	Pathogenic	0.573
NPHS1	O60500-1.1	P690G	Pathogenic	0.622
NPHS1	O60500-1.1	P690H	Neutral	0.493
NPHS1	O60500-1.1	P690I	Pathogenic	0.612
NPHS1	O60500-1.1	P690K	Pathogenic	0.92
NPHS1	O60500-1.1	P690L	Pathogenic	0.575
NPHS1	O60500-1.1	P690M	Pathogenic	0.501
NPHS1	O60500-1.1	P690N	Pathogenic	0.632
NPHS1	O60500-1.1	P690Q	Pathogenic	0.69
NPHS1	O60500-1.1	P690R	Pathogenic	0.915
NPHS1	O60500-1.1	P690S	Pathogenic	0.589
NPHS1	O60500-1.1	P690T	Neutral	0.4
NPHS1	O60500-1.1	P690V	Neutral	0.385
NPHS1	O60500-1.1	P690W	Pathogenic	0.838
NPHS1	O60500-1.1	P690Y	Neutral	0.402
NPHS1	O60500-1.1	A691C	Neutral	0.285
NPHS1	O60500-1.1	A691D	Neutral	0.268
NPHS1	O60500-1.1	A691E	Neutral	0.407
NPHS1	O60500-1.1	A691F	Pathogenic	0.654
NPHS1	O60500-1.1	A691G	Neutral	0.187
NPHS1	O60500-1.1	A691H	Neutral	0.154
NPHS1	O60500-1.1	A691I	Pathogenic	0.69
NPHS1	O60500-1.1	A691K	Pathogenic	0.682
NPHS1	O60500-1.1	A691L	Pathogenic	0.656
NPHS1	O60500-1.1	A691M	Neutral	0.487
NPHS1	O60500-1.1	A691N	Neutral	0.243
NPHS1	O60500-1.1	A691P	Neutral	0.165
NPHS1	O60500-1.1	A691Q	Neutral	0.294
NPHS1	O60500-1.1	A691R	Pathogenic	0.749
NPHS1	O60500-1.1	A691S	Neutral	0.211
NPHS1	O60500-1.1	A691T	Neutral	0.157
NPHS1	O60500-1.1	A691V	Neutral	0.469
NPHS1	O60500-1.1	A691W	Pathogenic	0.83
NPHS1	O60500-1.1	A691Y	Neutral	0.388
NPHS1	O60500-1.1	G692A	Pathogenic	0.9
NPHS1	O60500-1.1	G692C	Pathogenic	0.921
NPHS1	O60500-1.1	G692D	Pathogenic	0.955
NPHS1	O60500-1.1	G692E	Pathogenic	0.947
NPHS1	O60500-1.1	G692F	Pathogenic	0.992
NPHS1	O60500-1.1	G692H	Pathogenic	0.912
NPHS1	O60500-1.1	G692I	Pathogenic	0.985
NPHS1	O60500-1.1	G692K	Pathogenic	0.982
NPHS1	O60500-1.1	G692L	Pathogenic	0.982
NPHS1	O60500-1.1	G692M	Pathogenic	0.976
NPHS1	O60500-1.1	G692N	Pathogenic	0.965
NPHS1	O60500-1.1	G692P	Pathogenic	0.928
NPHS1	O60500-1.1	G692Q	Pathogenic	0.915
NPHS1	O60500-1.1	G692R	Pathogenic	0.987
NPHS1	O60500-1.1	G692S	Pathogenic	0.874
NPHS1	O60500-1.1	G692T	Pathogenic	0.874
NPHS1	O60500-1.1	G692V	Pathogenic	0.963
NPHS1	O60500-1.1	G692W	Pathogenic	0.999
NPHS1	O60500-1.1	G692Y	Pathogenic	0.976
NPHS1	O60500-1.1	G693A	Neutral	0.209
NPHS1	O60500-1.1	G693C	Neutral	0.254
NPHS1	O60500-1.1	G693D	Neutral	0.384
NPHS1	O60500-1.1	G693E	Neutral	0.344
NPHS1	O60500-1.1	G693F	Pathogenic	0.783
NPHS1	O60500-1.1	G693H	Neutral	0.234
NPHS1	O60500-1.1	G693I	Pathogenic	0.656
NPHS1	O60500-1.1	G693K	Pathogenic	0.621
NPHS1	O60500-1.1	G693L	Pathogenic	0.621
NPHS1	O60500-1.1	G693M	Pathogenic	0.548
NPHS1	O60500-1.1	G693N	Neutral	0.448
NPHS1	O60500-1.1	G693P	Neutral	0.274
NPHS1	O60500-1.1	G693Q	Neutral	0.241
NPHS1	O60500-1.1	G693R	Pathogenic	0.695
NPHS1	O60500-1.1	G693S	Neutral	0.169
NPHS1	O60500-1.1	G693T	Neutral	0.169
NPHS1	O60500-1.1	G693V	Neutral	0.431
NPHS1	O60500-1.1	G693W	Pathogenic	0.954
NPHS1	O60500-1.1	G693Y	Pathogenic	0.548
NPHS1	O60500-1.1	P694A	Pathogenic	0.852
NPHS1	O60500-1.1	P694C	Pathogenic	0.57
NPHS1	O60500-1.1	P694D	Pathogenic	0.944
NPHS1	O60500-1.1	P694E	Pathogenic	0.955
NPHS1	O60500-1.1	P694F	Pathogenic	0.886
NPHS1	O60500-1.1	P694G	Pathogenic	0.905
NPHS1	O60500-1.1	P694H	Pathogenic	0.849
NPHS1	O60500-1.1	P694I	Pathogenic	0.901
NPHS1	O60500-1.1	P694K	Pathogenic	0.985
NPHS1	O60500-1.1	P694L	Pathogenic	0.887
NPHS1	O60500-1.1	P694M	Pathogenic	0.853
NPHS1	O60500-1.1	P694N	Pathogenic	0.909
NPHS1	O60500-1.1	P694Q	Pathogenic	0.928
NPHS1	O60500-1.1	P694R	Pathogenic	0.984
NPHS1	O60500-1.1	P694S	Pathogenic	0.893
NPHS1	O60500-1.1	P694T	Pathogenic	0.794
NPHS1	O60500-1.1	P694V	Pathogenic	0.784
NPHS1	O60500-1.1	P694W	Pathogenic	0.968
NPHS1	O60500-1.1	P694Y	Pathogenic	0.796
NPHS1	O60500-1.1	R695A	Pathogenic	0.999
NPHS1	O60500-1.1	R695C	Pathogenic	0.998
NPHS1	O60500-1.1	R695D	Pathogenic	0.984
NPHS1	O60500-1.1	R695E	Pathogenic	0.991
NPHS1	O60500-1.1	R695F	Pathogenic	0.998
NPHS1	O60500-1.1	R695G	Pathogenic	0.998
NPHS1	O60500-1.1	R695H	Pathogenic	0.996
NPHS1	O60500-1.1	R695I	Pathogenic	0.999
NPHS1	O60500-1.1	R695K	Pathogenic	0.987
NPHS1	O60500-1.1	R695L	Pathogenic	0.999
NPHS1	O60500-1.1	R695M	Pathogenic	0.999
NPHS1	O60500-1.1	R695N	Pathogenic	0.994
NPHS1	O60500-1.1	R695P	Pathogenic	0.998
NPHS1	O60500-1.1	R695Q	Pathogenic	0.996
NPHS1	O60500-1.1	R695S	Pathogenic	0.998
NPHS1	O60500-1.1	R695T	Pathogenic	0.998
NPHS1	O60500-1.1	R695V	Pathogenic	0.998
NPHS1	O60500-1.1	R695W	Pathogenic	0.999
NPHS1	O60500-1.1	R695Y	Pathogenic	0.996
NPHS1	O60500-1.1	H696A	Pathogenic	0.991
NPHS1	O60500-1.1	H696C	Pathogenic	0.992
NPHS1	O60500-1.1	H696D	Pathogenic	0.996
NPHS1	O60500-1.1	H696E	Pathogenic	0.996
NPHS1	O60500-1.1	H696F	Pathogenic	0.999
NPHS1	O60500-1.1	H696G	Pathogenic	0.994
NPHS1	O60500-1.1	H696I	Pathogenic	0.996
NPHS1	O60500-1.1	H696K	Pathogenic	0.997
NPHS1	O60500-1.1	H696L	Pathogenic	0.995
NPHS1	O60500-1.1	H696M	Pathogenic	0.993
NPHS1	O60500-1.1	H696N	Pathogenic	0.998
NPHS1	O60500-1.1	H696P	Pathogenic	0.992
NPHS1	O60500-1.1	H696Q	Pathogenic	0.991
NPHS1	O60500-1.1	H696R	Pathogenic	0.998
NPHS1	O60500-1.1	H696S	Pathogenic	0.993
NPHS1	O60500-1.1	H696T	Pathogenic	0.982
NPHS1	O60500-1.1	H696V	Pathogenic	0.992
NPHS1	O60500-1.1	H696W	Pathogenic	0.999
NPHS1	O60500-1.1	H696Y	Pathogenic	0.999
NPHS1	O60500-1.1	R697A	Pathogenic	0.97
NPHS1	O60500-1.1	R697C	Pathogenic	0.962
NPHS1	O60500-1.1	R697D	Pathogenic	0.711
NPHS1	O60500-1.1	R697E	Pathogenic	0.813
NPHS1	O60500-1.1	R697F	Pathogenic	0.963
NPHS1	O60500-1.1	R697G	Pathogenic	0.955
NPHS1	O60500-1.1	R697H	Pathogenic	0.917
NPHS1	O60500-1.1	R697I	Pathogenic	0.972
NPHS1	O60500-1.1	R697K	Pathogenic	0.756
NPHS1	O60500-1.1	R697L	Pathogenic	0.978
NPHS1	O60500-1.1	R697M	Pathogenic	0.971
NPHS1	O60500-1.1	R697N	Pathogenic	0.862
NPHS1	O60500-1.1	R697P	Pathogenic	0.958
NPHS1	O60500-1.1	R697Q	Pathogenic	0.915
NPHS1	O60500-1.1	R697S	Pathogenic	0.943
NPHS1	O60500-1.1	R697T	Pathogenic	0.941
NPHS1	O60500-1.1	R697V	Pathogenic	0.958
NPHS1	O60500-1.1	R697W	Pathogenic	0.982
NPHS1	O60500-1.1	R697Y	Pathogenic	0.908
NPHS1	O60500-1.1	I698A	Pathogenic	0.961
NPHS1	O60500-1.1	I698C	Pathogenic	0.852
NPHS1	O60500-1.1	I698D	Pathogenic	0.969
NPHS1	O60500-1.1	I698E	Pathogenic	0.944
NPHS1	O60500-1.1	I698F	Pathogenic	0.577
NPHS1	O60500-1.1	I698G	Pathogenic	0.948
NPHS1	O60500-1.1	I698H	Pathogenic	0.811
NPHS1	O60500-1.1	I698K	Pathogenic	0.962
NPHS1	O60500-1.1	I698L	Pathogenic	0.727
NPHS1	O60500-1.1	I698M	Pathogenic	0.782
NPHS1	O60500-1.1	I698N	Pathogenic	0.956
NPHS1	O60500-1.1	I698P	Pathogenic	0.777
NPHS1	O60500-1.1	I698Q	Pathogenic	0.889
NPHS1	O60500-1.1	I698R	Pathogenic	0.973
NPHS1	O60500-1.1	I698S	Pathogenic	0.96
NPHS1	O60500-1.1	I698T	Pathogenic	0.935
NPHS1	O60500-1.1	I698V	Pathogenic	0.927
NPHS1	O60500-1.1	I698W	Pathogenic	0.602
NPHS1	O60500-1.1	I698Y	Pathogenic	0.783
NPHS1	O60500-1.1	L699A	Pathogenic	0.667
NPHS1	O60500-1.1	L699C	Neutral	0.319
NPHS1	O60500-1.1	L699D	Pathogenic	0.63
NPHS1	O60500-1.1	L699E	Pathogenic	0.577
NPHS1	O60500-1.1	L699F	Neutral	0.126
NPHS1	O60500-1.1	L699G	Pathogenic	0.599
NPHS1	O60500-1.1	L699H	Neutral	0.259
NPHS1	O60500-1.1	L699I	Neutral	0.202
NPHS1	O60500-1.1	L699K	Pathogenic	0.757
NPHS1	O60500-1.1	L699M	Neutral	0.304
NPHS1	O60500-1.1	L699N	Pathogenic	0.637
NPHS1	O60500-1.1	L699P	Neutral	0.221
NPHS1	O60500-1.1	L699Q	Neutral	0.492
NPHS1	O60500-1.1	L699R	Pathogenic	0.813
NPHS1	O60500-1.1	L699S	Pathogenic	0.66
NPHS1	O60500-1.1	L699T	Pathogenic	0.539
NPHS1	O60500-1.1	L699V	Neutral	0.319
NPHS1	O60500-1.1	L699W	Neutral	0.2
NPHS1	O60500-1.1	L699Y	Neutral	0.227
NPHS1	O60500-1.1	S700A	Neutral	0.074
NPHS1	O60500-1.1	S700C	Neutral	0.104
NPHS1	O60500-1.1	S700D	Neutral	0.113
NPHS1	O60500-1.1	S700E	Neutral	0.138
NPHS1	O60500-1.1	S700F	Neutral	0.452
NPHS1	O60500-1.1	S700G	Neutral	0.051
NPHS1	O60500-1.1	S700H	Neutral	0.065
NPHS1	O60500-1.1	S700I	Neutral	0.394
NPHS1	O60500-1.1	S700K	Neutral	0.333
NPHS1	O60500-1.1	S700L	Neutral	0.358
NPHS1	O60500-1.1	S700M	Neutral	0.293
NPHS1	O60500-1.1	S700N	Neutral	0.143
NPHS1	O60500-1.1	S700P	Neutral	0.079
NPHS1	O60500-1.1	S700Q	Neutral	0.088
NPHS1	O60500-1.1	S700R	Neutral	0.318
NPHS1	O60500-1.1	S700T	Neutral	0.094
NPHS1	O60500-1.1	S700V	Neutral	0.148
NPHS1	O60500-1.1	S700W	Pathogenic	0.68
NPHS1	O60500-1.1	S700Y	Neutral	0.217
NPHS1	O60500-1.1	S701A	Neutral	0.011
NPHS1	O60500-1.1	S701C	Neutral	0.015
NPHS1	O60500-1.1	S701D	Neutral	0.017
NPHS1	O60500-1.1	S701E	Neutral	0.021
NPHS1	O60500-1.1	S701F	Neutral	0.1
NPHS1	O60500-1.1	S701G	Neutral	0.007
NPHS1	O60500-1.1	S701H	Neutral	0.009
NPHS1	O60500-1.1	S701I	Neutral	0.081
NPHS1	O60500-1.1	S701K	Neutral	0.063
NPHS1	O60500-1.1	S701L	Neutral	0.07
NPHS1	O60500-1.1	S701M	Neutral	0.053
NPHS1	O60500-1.1	S701N	Neutral	0.022
NPHS1	O60500-1.1	S701P	Neutral	0.012
NPHS1	O60500-1.1	S701Q	Neutral	0.013
NPHS1	O60500-1.1	S701R	Neutral	0.059
NPHS1	O60500-1.1	S701T	Neutral	0.014
NPHS1	O60500-1.1	S701V	Neutral	0.023
NPHS1	O60500-1.1	S701W	Neutral	0.223
NPHS1	O60500-1.1	S701Y	Neutral	0.036
NPHS1	O60500-1.1	G702A	Pathogenic	0.849
NPHS1	O60500-1.1	G702C	Pathogenic	0.879
NPHS1	O60500-1.1	G702D	Pathogenic	0.93
NPHS1	O60500-1.1	G702E	Pathogenic	0.918
NPHS1	O60500-1.1	G702F	Pathogenic	0.987
NPHS1	O60500-1.1	G702H	Pathogenic	0.867
NPHS1	O60500-1.1	G702I	Pathogenic	0.976
NPHS1	O60500-1.1	G702K	Pathogenic	0.972
NPHS1	O60500-1.1	G702L	Pathogenic	0.972
NPHS1	O60500-1.1	G702M	Pathogenic	0.963
NPHS1	O60500-1.1	G702N	Pathogenic	0.945
NPHS1	O60500-1.1	G702P	Pathogenic	0.889
NPHS1	O60500-1.1	G702Q	Pathogenic	0.871
NPHS1	O60500-1.1	G702R	Pathogenic	0.98
NPHS1	O60500-1.1	G702S	Pathogenic	0.812
NPHS1	O60500-1.1	G702T	Pathogenic	0.813
NPHS1	O60500-1.1	G702V	Pathogenic	0.942
NPHS1	O60500-1.1	G702W	Pathogenic	0.998
NPHS1	O60500-1.1	G702Y	Pathogenic	0.963
NPHS1	O60500-1.1	A703C	Pathogenic	0.707
NPHS1	O60500-1.1	A703D	Pathogenic	0.689
NPHS1	O60500-1.1	A703E	Pathogenic	0.806
NPHS1	O60500-1.1	A703F	Pathogenic	0.92
NPHS1	O60500-1.1	A703G	Pathogenic	0.583
NPHS1	O60500-1.1	A703H	Pathogenic	0.523
NPHS1	O60500-1.1	A703I	Pathogenic	0.931
NPHS1	O60500-1.1	A703K	Pathogenic	0.929
NPHS1	O60500-1.1	A703L	Pathogenic	0.92
NPHS1	O60500-1.1	A703M	Pathogenic	0.852
NPHS1	O60500-1.1	A703N	Pathogenic	0.66
NPHS1	O60500-1.1	A703P	Pathogenic	0.545
NPHS1	O60500-1.1	A703Q	Pathogenic	0.716
NPHS1	O60500-1.1	A703R	Pathogenic	0.948
NPHS1	O60500-1.1	A703S	Pathogenic	0.618
NPHS1	O60500-1.1	A703T	Pathogenic	0.529
NPHS1	O60500-1.1	A703V	Pathogenic	0.842
NPHS1	O60500-1.1	A703W	Pathogenic	0.967
NPHS1	O60500-1.1	A703Y	Pathogenic	0.793
NPHS1	O60500-1.1	L704A	Pathogenic	0.995
NPHS1	O60500-1.1	L704C	Pathogenic	0.978
NPHS1	O60500-1.1	L704D	Pathogenic	0.994
NPHS1	O60500-1.1	L704E	Pathogenic	0.992
NPHS1	O60500-1.1	L704F	Pathogenic	0.932
NPHS1	O60500-1.1	L704G	Pathogenic	0.993
NPHS1	O60500-1.1	L704H	Pathogenic	0.971
NPHS1	O60500-1.1	L704I	Pathogenic	0.96
NPHS1	O60500-1.1	L704K	Pathogenic	0.997
NPHS1	O60500-1.1	L704M	Pathogenic	0.976
NPHS1	O60500-1.1	L704N	Pathogenic	0.994
NPHS1	O60500-1.1	L704P	Pathogenic	0.964
NPHS1	O60500-1.1	L704Q	Pathogenic	0.989
NPHS1	O60500-1.1	L704R	Pathogenic	0.998
NPHS1	O60500-1.1	L704S	Pathogenic	0.995
NPHS1	O60500-1.1	L704T	Pathogenic	0.991
NPHS1	O60500-1.1	L704V	Pathogenic	0.978
NPHS1	O60500-1.1	L704W	Pathogenic	0.959
NPHS1	O60500-1.1	L704Y	Pathogenic	0.965
NPHS1	O60500-1.1	H705A	Neutral	0.033
NPHS1	O60500-1.1	H705C	Neutral	0.039
NPHS1	O60500-1.1	H705D	Neutral	0.079
NPHS1	O60500-1.1	H705E	Neutral	0.064
NPHS1	O60500-1.1	H705F	Neutral	0.173
NPHS1	O60500-1.1	H705G	Neutral	0.048
NPHS1	O60500-1.1	H705I	Neutral	0.069
NPHS1	O60500-1.1	H705K	Neutral	0.086
NPHS1	O60500-1.1	H705L	Neutral	0.06
NPHS1	O60500-1.1	H705M	Neutral	0.045
NPHS1	O60500-1.1	H705N	Neutral	0.117
NPHS1	O60500-1.1	H705P	Neutral	0.036
NPHS1	O60500-1.1	H705Q	Neutral	0.032
NPHS1	O60500-1.1	H705R	Neutral	0.163
NPHS1	O60500-1.1	H705S	Neutral	0.042
NPHS1	O60500-1.1	H705T	Neutral	0.017
NPHS1	O60500-1.1	H705V	Neutral	0.035
NPHS1	O60500-1.1	H705W	Neutral	0.35
NPHS1	O60500-1.1	H705Y	Neutral	0.189
NPHS1	O60500-1.1	L706A	Pathogenic	0.833
NPHS1	O60500-1.1	L706C	Pathogenic	0.539
NPHS1	O60500-1.1	L706D	Pathogenic	0.809
NPHS1	O60500-1.1	L706E	Pathogenic	0.773
NPHS1	O60500-1.1	L706F	Neutral	0.265
NPHS1	O60500-1.1	L706G	Pathogenic	0.788
NPHS1	O60500-1.1	L706H	Neutral	0.466
NPHS1	O60500-1.1	L706I	Neutral	0.387
NPHS1	O60500-1.1	L706K	Pathogenic	0.886
NPHS1	O60500-1.1	L706M	Pathogenic	0.521
NPHS1	O60500-1.1	L706N	Pathogenic	0.814
NPHS1	O60500-1.1	L706P	Neutral	0.414
NPHS1	O60500-1.1	L706Q	Pathogenic	0.707
NPHS1	O60500-1.1	L706R	Pathogenic	0.915
NPHS1	O60500-1.1	L706S	Pathogenic	0.829
NPHS1	O60500-1.1	L706T	Pathogenic	0.744
NPHS1	O60500-1.1	L706V	Pathogenic	0.539
NPHS1	O60500-1.1	L706W	Neutral	0.384
NPHS1	O60500-1.1	L706Y	Neutral	0.423
NPHS1	O60500-1.1	W707A	Pathogenic	1.0
NPHS1	O60500-1.1	W707C	Pathogenic	1.0
NPHS1	O60500-1.1	W707D	Pathogenic	1.0
NPHS1	O60500-1.1	W707E	Pathogenic	1.0
NPHS1	O60500-1.1	W707F	Pathogenic	0.999
NPHS1	O60500-1.1	W707G	Pathogenic	1.0
NPHS1	O60500-1.1	W707H	Pathogenic	1.0
NPHS1	O60500-1.1	W707I	Pathogenic	0.995
NPHS1	O60500-1.1	W707K	Pathogenic	1.0
NPHS1	O60500-1.1	W707L	Pathogenic	0.997
NPHS1	O60500-1.1	W707M	Pathogenic	0.999
NPHS1	O60500-1.1	W707N	Pathogenic	1.0
NPHS1	O60500-1.1	W707P	Pathogenic	0.999
NPHS1	O60500-1.1	W707Q	Pathogenic	1.0
NPHS1	O60500-1.1	W707R	Pathogenic	1.0
NPHS1	O60500-1.1	W707S	Pathogenic	1.0
NPHS1	O60500-1.1	W707T	Pathogenic	1.0
NPHS1	O60500-1.1	W707V	Pathogenic	0.999
NPHS1	O60500-1.1	W707Y	Pathogenic	1.0
NPHS1	O60500-1.1	N708A	Pathogenic	0.916
NPHS1	O60500-1.1	N708C	Pathogenic	0.928
NPHS1	O60500-1.1	N708D	Pathogenic	0.873
NPHS1	O60500-1.1	N708E	Pathogenic	0.82
NPHS1	O60500-1.1	N708F	Pathogenic	0.988
NPHS1	O60500-1.1	N708G	Pathogenic	0.96
NPHS1	O60500-1.1	N708H	Pathogenic	0.96
NPHS1	O60500-1.1	N708I	Pathogenic	0.985
NPHS1	O60500-1.1	N708K	Pathogenic	0.934
NPHS1	O60500-1.1	N708L	Pathogenic	0.983
NPHS1	O60500-1.1	N708M	Pathogenic	0.977
NPHS1	O60500-1.1	N708P	Pathogenic	0.921
NPHS1	O60500-1.1	N708Q	Pathogenic	0.895
NPHS1	O60500-1.1	N708R	Pathogenic	0.952
NPHS1	O60500-1.1	N708S	Pathogenic	0.95
NPHS1	O60500-1.1	N708T	Pathogenic	0.924
NPHS1	O60500-1.1	N708V	Pathogenic	0.947
NPHS1	O60500-1.1	N708W	Pathogenic	0.995
NPHS1	O60500-1.1	N708Y	Pathogenic	0.977
NPHS1	O60500-1.1	V709A	Pathogenic	0.983
NPHS1	O60500-1.1	V709C	Pathogenic	0.902
NPHS1	O60500-1.1	V709D	Pathogenic	0.98
NPHS1	O60500-1.1	V709E	Pathogenic	0.98
NPHS1	O60500-1.1	V709F	Pathogenic	0.952
NPHS1	O60500-1.1	V709G	Pathogenic	0.978
NPHS1	O60500-1.1	V709H	Pathogenic	0.927
NPHS1	O60500-1.1	V709I	Pathogenic	0.987
NPHS1	O60500-1.1	V709K	Pathogenic	0.993
NPHS1	O60500-1.1	V709L	Pathogenic	0.967
NPHS1	O60500-1.1	V709M	Pathogenic	0.936
NPHS1	O60500-1.1	V709N	Pathogenic	0.972
NPHS1	O60500-1.1	V709P	Pathogenic	0.893
NPHS1	O60500-1.1	V709Q	Pathogenic	0.967
NPHS1	O60500-1.1	V709R	Pathogenic	0.993
NPHS1	O60500-1.1	V709S	Pathogenic	0.974
NPHS1	O60500-1.1	V709T	Pathogenic	0.972
NPHS1	O60500-1.1	V709W	Pathogenic	0.972
NPHS1	O60500-1.1	V709Y	Pathogenic	0.934
NPHS1	O60500-1.1	T710A	Pathogenic	0.928
NPHS1	O60500-1.1	T710C	Pathogenic	0.938
NPHS1	O60500-1.1	T710D	Pathogenic	0.955
NPHS1	O60500-1.1	T710E	Pathogenic	0.96
NPHS1	O60500-1.1	T710F	Pathogenic	0.987
NPHS1	O60500-1.1	T710G	Pathogenic	0.925
NPHS1	O60500-1.1	T710H	Pathogenic	0.864
NPHS1	O60500-1.1	T710I	Pathogenic	0.989
NPHS1	O60500-1.1	T710K	Pathogenic	0.987
NPHS1	O60500-1.1	T710L	Pathogenic	0.987
NPHS1	O60500-1.1	T710M	Pathogenic	0.975
NPHS1	O60500-1.1	T710N	Pathogenic	0.961
NPHS1	O60500-1.1	T710P	Pathogenic	0.903
NPHS1	O60500-1.1	T710Q	Pathogenic	0.936
NPHS1	O60500-1.1	T710R	Pathogenic	0.99
NPHS1	O60500-1.1	T710S	Pathogenic	0.96
NPHS1	O60500-1.1	T710V	Pathogenic	0.973
NPHS1	O60500-1.1	T710W	Pathogenic	0.997
NPHS1	O60500-1.1	T710Y	Pathogenic	0.963
NPHS1	O60500-1.1	R711A	Pathogenic	0.998
NPHS1	O60500-1.1	R711C	Pathogenic	0.997
NPHS1	O60500-1.1	R711D	Pathogenic	0.97
NPHS1	O60500-1.1	R711E	Pathogenic	0.983
NPHS1	O60500-1.1	R711F	Pathogenic	0.997
NPHS1	O60500-1.1	R711G	Pathogenic	0.996
NPHS1	O60500-1.1	R711H	Pathogenic	0.993
NPHS1	O60500-1.1	R711I	Pathogenic	0.998
NPHS1	O60500-1.1	R711K	Pathogenic	0.976
NPHS1	O60500-1.1	R711L	Pathogenic	0.998
NPHS1	O60500-1.1	R711M	Pathogenic	0.998
NPHS1	O60500-1.1	R711N	Pathogenic	0.988
NPHS1	O60500-1.1	R711P	Pathogenic	0.997
NPHS1	O60500-1.1	R711Q	Pathogenic	0.993
NPHS1	O60500-1.1	R711S	Pathogenic	0.995
NPHS1	O60500-1.1	R711T	Pathogenic	0.995
NPHS1	O60500-1.1	R711V	Pathogenic	0.997
NPHS1	O60500-1.1	R711W	Pathogenic	0.999
NPHS1	O60500-1.1	R711Y	Pathogenic	0.992
NPHS1	O60500-1.1	A712C	Pathogenic	0.777
NPHS1	O60500-1.1	A712D	Pathogenic	0.763
NPHS1	O60500-1.1	A712E	Pathogenic	0.858
NPHS1	O60500-1.1	A712F	Pathogenic	0.943
NPHS1	O60500-1.1	A712G	Pathogenic	0.669
NPHS1	O60500-1.1	A712H	Pathogenic	0.614
NPHS1	O60500-1.1	A712I	Pathogenic	0.951
NPHS1	O60500-1.1	A712K	Pathogenic	0.95
NPHS1	O60500-1.1	A712L	Pathogenic	0.944
NPHS1	O60500-1.1	A712M	Pathogenic	0.893
NPHS1	O60500-1.1	A712N	Pathogenic	0.738
NPHS1	O60500-1.1	A712P	Pathogenic	0.635
NPHS1	O60500-1.1	A712Q	Pathogenic	0.785
NPHS1	O60500-1.1	A712R	Pathogenic	0.963
NPHS1	O60500-1.1	A712S	Pathogenic	0.701
NPHS1	O60500-1.1	A712T	Pathogenic	0.62
NPHS1	O60500-1.1	A712V	Pathogenic	0.886
NPHS1	O60500-1.1	A712W	Pathogenic	0.977
NPHS1	O60500-1.1	A712Y	Pathogenic	0.848
NPHS1	O60500-1.1	D713A	Pathogenic	0.996
NPHS1	O60500-1.1	D713C	Pathogenic	0.997
NPHS1	O60500-1.1	D713E	Pathogenic	0.996
NPHS1	O60500-1.1	D713F	Pathogenic	1.0
NPHS1	O60500-1.1	D713G	Pathogenic	0.997
NPHS1	O60500-1.1	D713H	Pathogenic	0.997
NPHS1	O60500-1.1	D713I	Pathogenic	0.999
NPHS1	O60500-1.1	D713K	Pathogenic	0.994
NPHS1	O60500-1.1	D713L	Pathogenic	0.999
NPHS1	O60500-1.1	D713M	Pathogenic	0.999
NPHS1	O60500-1.1	D713N	Pathogenic	0.993
NPHS1	O60500-1.1	D713P	Pathogenic	0.998
NPHS1	O60500-1.1	D713Q	Pathogenic	0.996
NPHS1	O60500-1.1	D713R	Pathogenic	0.994
NPHS1	O60500-1.1	D713S	Pathogenic	0.997
NPHS1	O60500-1.1	D713T	Pathogenic	0.995
NPHS1	O60500-1.1	D713V	Pathogenic	0.998
NPHS1	O60500-1.1	D713W	Pathogenic	1.0
NPHS1	O60500-1.1	D713Y	Pathogenic	0.999
NPHS1	O60500-1.1	D714A	Neutral	0.302
NPHS1	O60500-1.1	D714C	Neutral	0.336
NPHS1	O60500-1.1	D714E	Neutral	0.313
NPHS1	O60500-1.1	D714F	Pathogenic	0.808
NPHS1	O60500-1.1	D714G	Neutral	0.39
NPHS1	O60500-1.1	D714H	Neutral	0.348
NPHS1	O60500-1.1	D714I	Pathogenic	0.769
NPHS1	O60500-1.1	D714K	Neutral	0.224
NPHS1	O60500-1.1	D714L	Pathogenic	0.657
NPHS1	O60500-1.1	D714M	Pathogenic	0.587
NPHS1	O60500-1.1	D714N	Neutral	0.191
NPHS1	O60500-1.1	D714P	Neutral	0.408
NPHS1	O60500-1.1	D714Q	Neutral	0.3
NPHS1	O60500-1.1	D714R	Neutral	0.212
NPHS1	O60500-1.1	D714S	Neutral	0.333
NPHS1	O60500-1.1	D714T	Neutral	0.262
NPHS1	O60500-1.1	D714V	Neutral	0.47
NPHS1	O60500-1.1	D714W	Pathogenic	0.916
NPHS1	O60500-1.1	D714Y	Pathogenic	0.586
NPHS1	O60500-1.1	G715A	Pathogenic	0.982
NPHS1	O60500-1.1	G715C	Pathogenic	0.986
NPHS1	O60500-1.1	G715D	Pathogenic	0.992
NPHS1	O60500-1.1	G715E	Pathogenic	0.991
NPHS1	O60500-1.1	G715F	Pathogenic	0.999
NPHS1	O60500-1.1	G715H	Pathogenic	0.984
NPHS1	O60500-1.1	G715I	Pathogenic	0.997
NPHS1	O60500-1.1	G715K	Pathogenic	0.997
NPHS1	O60500-1.1	G715L	Pathogenic	0.997
NPHS1	O60500-1.1	G715M	Pathogenic	0.996
NPHS1	O60500-1.1	G715N	Pathogenic	0.994
NPHS1	O60500-1.1	G715P	Pathogenic	0.987
NPHS1	O60500-1.1	G715Q	Pathogenic	0.985
NPHS1	O60500-1.1	G715R	Pathogenic	0.998
NPHS1	O60500-1.1	G715S	Pathogenic	0.976
NPHS1	O60500-1.1	G715T	Pathogenic	0.977
NPHS1	O60500-1.1	G715V	Pathogenic	0.994
NPHS1	O60500-1.1	G715W	Pathogenic	1.0
NPHS1	O60500-1.1	G715Y	Pathogenic	0.996
NPHS1	O60500-1.1	L716A	Neutral	0.027
NPHS1	O60500-1.1	L716C	Neutral	0.006
NPHS1	O60500-1.1	L716D	Neutral	0.023
NPHS1	O60500-1.1	L716E	Neutral	0.018
NPHS1	O60500-1.1	L716F	Neutral	0.002
NPHS1	O60500-1.1	L716G	Neutral	0.02
NPHS1	O60500-1.1	L716H	Neutral	0.005
NPHS1	O60500-1.1	L716I	Neutral	0.003
NPHS1	O60500-1.1	L716K	Neutral	0.041
NPHS1	O60500-1.1	L716M	Neutral	0.006
NPHS1	O60500-1.1	L716N	Neutral	0.023
NPHS1	O60500-1.1	L716P	Neutral	0.004
NPHS1	O60500-1.1	L716Q	Neutral	0.013
NPHS1	O60500-1.1	L716R	Neutral	0.056
NPHS1	O60500-1.1	L716S	Neutral	0.026
NPHS1	O60500-1.1	L716T	Neutral	0.016
NPHS1	O60500-1.1	L716V	Neutral	0.006
NPHS1	O60500-1.1	L716W	Neutral	0.003
NPHS1	O60500-1.1	L716Y	Neutral	0.004
NPHS1	O60500-1.1	Y717A	Pathogenic	0.999
NPHS1	O60500-1.1	Y717C	Pathogenic	0.998
NPHS1	O60500-1.1	Y717D	Pathogenic	1.0
NPHS1	O60500-1.1	Y717E	Pathogenic	1.0
NPHS1	O60500-1.1	Y717F	Pathogenic	1.0
NPHS1	O60500-1.1	Y717G	Pathogenic	1.0
NPHS1	O60500-1.1	Y717H	Pathogenic	1.0
NPHS1	O60500-1.1	Y717I	Pathogenic	0.999
NPHS1	O60500-1.1	Y717K	Pathogenic	1.0
NPHS1	O60500-1.1	Y717L	Pathogenic	0.999
NPHS1	O60500-1.1	Y717M	Pathogenic	0.997
NPHS1	O60500-1.1	Y717N	Pathogenic	1.0
NPHS1	O60500-1.1	Y717P	Pathogenic	0.997
NPHS1	O60500-1.1	Y717Q	Pathogenic	0.999
NPHS1	O60500-1.1	Y717R	Pathogenic	1.0
NPHS1	O60500-1.1	Y717S	Pathogenic	1.0
NPHS1	O60500-1.1	Y717T	Pathogenic	0.999
NPHS1	O60500-1.1	Y717V	Pathogenic	0.998
NPHS1	O60500-1.1	Y717W	Pathogenic	1.0
NPHS1	O60500-1.1	Q718A	Pathogenic	0.57
NPHS1	O60500-1.1	Q718C	Pathogenic	0.509
NPHS1	O60500-1.1	Q718D	Pathogenic	0.537
NPHS1	O60500-1.1	Q718E	Pathogenic	0.58
NPHS1	O60500-1.1	Q718F	Pathogenic	0.745
NPHS1	O60500-1.1	Q718G	Neutral	0.468
NPHS1	O60500-1.1	Q718H	Neutral	0.355
NPHS1	O60500-1.1	Q718I	Pathogenic	0.697
NPHS1	O60500-1.1	Q718K	Pathogenic	0.696
NPHS1	O60500-1.1	Q718L	Pathogenic	0.746
NPHS1	O60500-1.1	Q718M	Pathogenic	0.765
NPHS1	O60500-1.1	Q718N	Neutral	0.445
NPHS1	O60500-1.1	Q718P	Pathogenic	0.586
NPHS1	O60500-1.1	Q718R	Pathogenic	0.76
NPHS1	O60500-1.1	Q718S	Pathogenic	0.507
NPHS1	O60500-1.1	Q718T	Neutral	0.399
NPHS1	O60500-1.1	Q718V	Pathogenic	0.583
NPHS1	O60500-1.1	Q718W	Pathogenic	0.944
NPHS1	O60500-1.1	Q718Y	Pathogenic	0.686
NPHS1	O60500-1.1	L719A	Pathogenic	0.652
NPHS1	O60500-1.1	L719C	Neutral	0.305
NPHS1	O60500-1.1	L719D	Pathogenic	0.614
NPHS1	O60500-1.1	L719E	Pathogenic	0.561
NPHS1	O60500-1.1	L719F	Neutral	0.119
NPHS1	O60500-1.1	L719G	Pathogenic	0.583
NPHS1	O60500-1.1	L719H	Neutral	0.247
NPHS1	O60500-1.1	L719I	Neutral	0.191
NPHS1	O60500-1.1	L719K	Pathogenic	0.745
NPHS1	O60500-1.1	L719M	Neutral	0.29
NPHS1	O60500-1.1	L719N	Pathogenic	0.622
NPHS1	O60500-1.1	L719P	Neutral	0.21
NPHS1	O60500-1.1	L719Q	Neutral	0.476
NPHS1	O60500-1.1	L719R	Pathogenic	0.802
NPHS1	O60500-1.1	L719S	Pathogenic	0.645
NPHS1	O60500-1.1	L719T	Pathogenic	0.522
NPHS1	O60500-1.1	L719V	Neutral	0.305
NPHS1	O60500-1.1	L719W	Neutral	0.19
NPHS1	O60500-1.1	L719Y	Neutral	0.216
NPHS1	O60500-1.1	H720A	Pathogenic	0.536
NPHS1	O60500-1.1	H720C	Pathogenic	0.574
NPHS1	O60500-1.1	H720D	Pathogenic	0.742
NPHS1	O60500-1.1	H720E	Pathogenic	0.697
NPHS1	O60500-1.1	H720F	Pathogenic	0.875
NPHS1	O60500-1.1	H720G	Pathogenic	0.629
NPHS1	O60500-1.1	H720I	Pathogenic	0.712
NPHS1	O60500-1.1	H720K	Pathogenic	0.759
NPHS1	O60500-1.1	H720L	Pathogenic	0.68
NPHS1	O60500-1.1	H720M	Pathogenic	0.612
NPHS1	O60500-1.1	H720N	Pathogenic	0.815
NPHS1	O60500-1.1	H720P	Pathogenic	0.552
NPHS1	O60500-1.1	H720Q	Pathogenic	0.523
NPHS1	O60500-1.1	H720R	Pathogenic	0.867
NPHS1	O60500-1.1	H720S	Pathogenic	0.596
NPHS1	O60500-1.1	H720T	Neutral	0.366
NPHS1	O60500-1.1	H720V	Pathogenic	0.549
NPHS1	O60500-1.1	H720W	Pathogenic	0.947
NPHS1	O60500-1.1	H720Y	Pathogenic	0.886
NPHS1	O60500-1.1	C721A	Pathogenic	0.999
NPHS1	O60500-1.1	C721D	Pathogenic	0.999
NPHS1	O60500-1.1	C721E	Pathogenic	0.999
NPHS1	O60500-1.1	C721F	Pathogenic	0.999
NPHS1	O60500-1.1	C721G	Pathogenic	0.999
NPHS1	O60500-1.1	C721H	Pathogenic	0.999
NPHS1	O60500-1.1	C721I	Pathogenic	0.999
NPHS1	O60500-1.1	C721K	Pathogenic	1.0
NPHS1	O60500-1.1	C721L	Pathogenic	0.999
NPHS1	O60500-1.1	C721M	Pathogenic	0.999
NPHS1	O60500-1.1	C721N	Pathogenic	0.999
NPHS1	O60500-1.1	C721P	Pathogenic	0.993
NPHS1	O60500-1.1	C721Q	Pathogenic	0.999
NPHS1	O60500-1.1	C721R	Pathogenic	1.0
NPHS1	O60500-1.1	C721S	Pathogenic	0.999
NPHS1	O60500-1.1	C721T	Pathogenic	0.999
NPHS1	O60500-1.1	C721V	Pathogenic	0.998
NPHS1	O60500-1.1	C721W	Pathogenic	1.0
NPHS1	O60500-1.1	C721Y	Pathogenic	0.998
NPHS1	O60500-1.1	Q722A	Pathogenic	0.591
NPHS1	O60500-1.1	Q722C	Pathogenic	0.531
NPHS1	O60500-1.1	Q722D	Pathogenic	0.559
NPHS1	O60500-1.1	Q722E	Pathogenic	0.602
NPHS1	O60500-1.1	Q722F	Pathogenic	0.761
NPHS1	O60500-1.1	Q722G	Neutral	0.49
NPHS1	O60500-1.1	Q722H	Neutral	0.376
NPHS1	O60500-1.1	Q722I	Pathogenic	0.715
NPHS1	O60500-1.1	Q722K	Pathogenic	0.714
NPHS1	O60500-1.1	Q722L	Pathogenic	0.763
NPHS1	O60500-1.1	Q722M	Pathogenic	0.781
NPHS1	O60500-1.1	Q722N	Neutral	0.467
NPHS1	O60500-1.1	Q722P	Pathogenic	0.608
NPHS1	O60500-1.1	Q722R	Pathogenic	0.776
NPHS1	O60500-1.1	Q722S	Pathogenic	0.529
NPHS1	O60500-1.1	Q722T	Neutral	0.42
NPHS1	O60500-1.1	Q722V	Pathogenic	0.605
NPHS1	O60500-1.1	Q722W	Pathogenic	0.948
NPHS1	O60500-1.1	Q722Y	Pathogenic	0.704
NPHS1	O60500-1.1	N723A	Pathogenic	0.998
NPHS1	O60500-1.1	N723C	Pathogenic	0.998
NPHS1	O60500-1.1	N723D	Pathogenic	0.996
NPHS1	O60500-1.1	N723E	Pathogenic	0.994
NPHS1	O60500-1.1	N723F	Pathogenic	1.0
NPHS1	O60500-1.1	N723G	Pathogenic	0.999
NPHS1	O60500-1.1	N723H	Pathogenic	0.999
NPHS1	O60500-1.1	N723I	Pathogenic	1.0
NPHS1	O60500-1.1	N723K	Pathogenic	0.998
NPHS1	O60500-1.1	N723L	Pathogenic	1.0
NPHS1	O60500-1.1	N723M	Pathogenic	0.999
NPHS1	O60500-1.1	N723P	Pathogenic	0.998
NPHS1	O60500-1.1	N723Q	Pathogenic	0.997
NPHS1	O60500-1.1	N723R	Pathogenic	0.999
NPHS1	O60500-1.1	N723S	Pathogenic	0.999
NPHS1	O60500-1.1	N723T	Pathogenic	0.998
NPHS1	O60500-1.1	N723V	Pathogenic	0.999
NPHS1	O60500-1.1	N723W	Pathogenic	1.0
NPHS1	O60500-1.1	N723Y	Pathogenic	0.999
NPHS1	O60500-1.1	S724A	Neutral	0.058
NPHS1	O60500-1.1	S724C	Neutral	0.081
NPHS1	O60500-1.1	S724D	Neutral	0.089
NPHS1	O60500-1.1	S724E	Neutral	0.109
NPHS1	O60500-1.1	S724F	Neutral	0.386
NPHS1	O60500-1.1	S724G	Neutral	0.039
NPHS1	O60500-1.1	S724H	Neutral	0.051
NPHS1	O60500-1.1	S724I	Neutral	0.331
NPHS1	O60500-1.1	S724K	Neutral	0.276
NPHS1	O60500-1.1	S724L	Neutral	0.298
NPHS1	O60500-1.1	S724M	Neutral	0.24
NPHS1	O60500-1.1	S724N	Neutral	0.113
NPHS1	O60500-1.1	S724P	Neutral	0.062
NPHS1	O60500-1.1	S724Q	Neutral	0.069
NPHS1	O60500-1.1	S724R	Neutral	0.262
NPHS1	O60500-1.1	S724T	Neutral	0.073
NPHS1	O60500-1.1	S724V	Neutral	0.117
NPHS1	O60500-1.1	S724W	Pathogenic	0.619
NPHS1	O60500-1.1	S724Y	Neutral	0.174
NPHS1	O60500-1.1	E725A	Pathogenic	0.99
NPHS1	O60500-1.1	E725C	Pathogenic	0.981
NPHS1	O60500-1.1	E725D	Pathogenic	0.982
NPHS1	O60500-1.1	E725F	Pathogenic	0.996
NPHS1	O60500-1.1	E725G	Pathogenic	0.985
NPHS1	O60500-1.1	E725H	Pathogenic	0.981
NPHS1	O60500-1.1	E725I	Pathogenic	0.995
NPHS1	O60500-1.1	E725K	Pathogenic	0.984
NPHS1	O60500-1.1	E725L	Pathogenic	0.995
NPHS1	O60500-1.1	E725M	Pathogenic	0.993
NPHS1	O60500-1.1	E725N	Pathogenic	0.949
NPHS1	O60500-1.1	E725P	Pathogenic	0.99
NPHS1	O60500-1.1	E725Q	Pathogenic	0.984
NPHS1	O60500-1.1	E725R	Pathogenic	0.983
NPHS1	O60500-1.1	E725S	Pathogenic	0.987
NPHS1	O60500-1.1	E725T	Pathogenic	0.98
NPHS1	O60500-1.1	E725V	Pathogenic	0.99
NPHS1	O60500-1.1	E725W	Pathogenic	0.999
NPHS1	O60500-1.1	E725Y	Pathogenic	0.993
NPHS1	O60500-1.1	G726A	Pathogenic	0.977
NPHS1	O60500-1.1	G726C	Pathogenic	0.982
NPHS1	O60500-1.1	G726D	Pathogenic	0.99
NPHS1	O60500-1.1	G726E	Pathogenic	0.988
NPHS1	O60500-1.1	G726F	Pathogenic	0.998
NPHS1	O60500-1.1	G726H	Pathogenic	0.98
NPHS1	O60500-1.1	G726I	Pathogenic	0.997
NPHS1	O60500-1.1	G726K	Pathogenic	0.996
NPHS1	O60500-1.1	G726L	Pathogenic	0.996
NPHS1	O60500-1.1	G726M	Pathogenic	0.995
NPHS1	O60500-1.1	G726N	Pathogenic	0.992
NPHS1	O60500-1.1	G726P	Pathogenic	0.984
NPHS1	O60500-1.1	G726Q	Pathogenic	0.981
NPHS1	O60500-1.1	G726R	Pathogenic	0.997
NPHS1	O60500-1.1	G726S	Pathogenic	0.97
NPHS1	O60500-1.1	G726T	Pathogenic	0.97
NPHS1	O60500-1.1	G726V	Pathogenic	0.992
NPHS1	O60500-1.1	G726W	Pathogenic	1.0
NPHS1	O60500-1.1	G726Y	Pathogenic	0.995
NPHS1	O60500-1.1	T727A	Neutral	0.087
NPHS1	O60500-1.1	T727C	Neutral	0.1
NPHS1	O60500-1.1	T727D	Neutral	0.134
NPHS1	O60500-1.1	T727E	Neutral	0.15
NPHS1	O60500-1.1	T727F	Neutral	0.362
NPHS1	O60500-1.1	T727G	Neutral	0.083
NPHS1	O60500-1.1	T727H	Neutral	0.045
NPHS1	O60500-1.1	T727I	Neutral	0.4
NPHS1	O60500-1.1	T727K	Neutral	0.356
NPHS1	O60500-1.1	T727L	Neutral	0.364
NPHS1	O60500-1.1	T727M	Neutral	0.221
NPHS1	O60500-1.1	T727N	Neutral	0.155
NPHS1	O60500-1.1	T727P	Neutral	0.064
NPHS1	O60500-1.1	T727Q	Neutral	0.097
NPHS1	O60500-1.1	T727R	Neutral	0.434
NPHS1	O60500-1.1	T727S	Neutral	0.15
NPHS1	O60500-1.1	T727V	Neutral	0.209
NPHS1	O60500-1.1	T727W	Pathogenic	0.686
NPHS1	O60500-1.1	T727Y	Neutral	0.16
NPHS1	O60500-1.1	A728C	Pathogenic	0.595
NPHS1	O60500-1.1	A728D	Pathogenic	0.575
NPHS1	O60500-1.1	A728E	Pathogenic	0.718
NPHS1	O60500-1.1	A728F	Pathogenic	0.875
NPHS1	O60500-1.1	A728G	Neutral	0.46
NPHS1	O60500-1.1	A728H	Neutral	0.401
NPHS1	O60500-1.1	A728I	Pathogenic	0.891
NPHS1	O60500-1.1	A728K	Pathogenic	0.888
NPHS1	O60500-1.1	A728L	Pathogenic	0.876
NPHS1	O60500-1.1	A728M	Pathogenic	0.778
NPHS1	O60500-1.1	A728N	Pathogenic	0.543
NPHS1	O60500-1.1	A728P	Neutral	0.422
NPHS1	O60500-1.1	A728Q	Pathogenic	0.606
NPHS1	O60500-1.1	A728R	Pathogenic	0.917
NPHS1	O60500-1.1	A728S	Neutral	0.497
NPHS1	O60500-1.1	A728T	Neutral	0.407
NPHS1	O60500-1.1	A728V	Pathogenic	0.766
NPHS1	O60500-1.1	A728W	Pathogenic	0.947
NPHS1	O60500-1.1	A728Y	Pathogenic	0.701
NPHS1	O60500-1.1	E729A	Pathogenic	0.958
NPHS1	O60500-1.1	E729C	Pathogenic	0.924
NPHS1	O60500-1.1	E729D	Pathogenic	0.928
NPHS1	O60500-1.1	E729F	Pathogenic	0.985
NPHS1	O60500-1.1	E729G	Pathogenic	0.939
NPHS1	O60500-1.1	E729H	Pathogenic	0.924
NPHS1	O60500-1.1	E729I	Pathogenic	0.981
NPHS1	O60500-1.1	E729K	Pathogenic	0.936
NPHS1	O60500-1.1	E729L	Pathogenic	0.978
NPHS1	O60500-1.1	E729M	Pathogenic	0.97
NPHS1	O60500-1.1	E729N	Pathogenic	0.818
NPHS1	O60500-1.1	E729P	Pathogenic	0.961
NPHS1	O60500-1.1	E729Q	Pathogenic	0.936
NPHS1	O60500-1.1	E729R	Pathogenic	0.931
NPHS1	O60500-1.1	E729S	Pathogenic	0.947
NPHS1	O60500-1.1	E729T	Pathogenic	0.92
NPHS1	O60500-1.1	E729V	Pathogenic	0.961
NPHS1	O60500-1.1	E729W	Pathogenic	0.996
NPHS1	O60500-1.1	E729Y	Pathogenic	0.97
NPHS1	O60500-1.1	A730C	Pathogenic	0.533
NPHS1	O60500-1.1	A730D	Pathogenic	0.513
NPHS1	O60500-1.1	A730E	Pathogenic	0.664
NPHS1	O60500-1.1	A730F	Pathogenic	0.844
NPHS1	O60500-1.1	A730G	Neutral	0.398
NPHS1	O60500-1.1	A730H	Neutral	0.342
NPHS1	O60500-1.1	A730I	Pathogenic	0.864
NPHS1	O60500-1.1	A730K	Pathogenic	0.86
NPHS1	O60500-1.1	A730L	Pathogenic	0.846
NPHS1	O60500-1.1	A730M	Pathogenic	0.731
NPHS1	O60500-1.1	A730N	Neutral	0.48
NPHS1	O60500-1.1	A730P	Neutral	0.362
NPHS1	O60500-1.1	A730Q	Pathogenic	0.544
NPHS1	O60500-1.1	A730R	Pathogenic	0.895
NPHS1	O60500-1.1	A730S	Neutral	0.434
NPHS1	O60500-1.1	A730T	Neutral	0.348
NPHS1	O60500-1.1	A730V	Pathogenic	0.717
NPHS1	O60500-1.1	A730W	Pathogenic	0.933
NPHS1	O60500-1.1	A730Y	Pathogenic	0.646
NPHS1	O60500-1.1	R731A	Neutral	0.004
NPHS1	O60500-1.1	R731C	Neutral	0.003
NPHS1	O60500-1.1	R731D	Neutral	0.0
NPHS1	O60500-1.1	R731E	Neutral	0.001
NPHS1	O60500-1.1	R731F	Neutral	0.003
NPHS1	O60500-1.1	R731G	Neutral	0.003
NPHS1	O60500-1.1	R731H	Neutral	0.001
NPHS1	O60500-1.1	R731I	Neutral	0.005
NPHS1	O60500-1.1	R731K	Neutral	0.0
NPHS1	O60500-1.1	R731L	Neutral	0.006
NPHS1	O60500-1.1	R731M	Neutral	0.004
NPHS1	O60500-1.1	R731N	Neutral	0.001
NPHS1	O60500-1.1	R731P	Neutral	0.003
NPHS1	O60500-1.1	R731Q	Neutral	0.001
NPHS1	O60500-1.1	R731S	Neutral	0.002
NPHS1	O60500-1.1	R731T	Neutral	0.002
NPHS1	O60500-1.1	R731V	Neutral	0.003
NPHS1	O60500-1.1	R731W	Neutral	0.007
NPHS1	O60500-1.1	R731Y	Neutral	0.001
NPHS1	O60500-1.1	L732A	Neutral	0.298
NPHS1	O60500-1.1	L732C	Neutral	0.091
NPHS1	O60500-1.1	L732D	Neutral	0.266
NPHS1	O60500-1.1	L732E	Neutral	0.225
NPHS1	O60500-1.1	L732F	Neutral	0.03
NPHS1	O60500-1.1	L732G	Neutral	0.241
NPHS1	O60500-1.1	L732H	Neutral	0.069
NPHS1	O60500-1.1	L732I	Neutral	0.051
NPHS1	O60500-1.1	L732K	Neutral	0.399
NPHS1	O60500-1.1	L732M	Neutral	0.085
NPHS1	O60500-1.1	L732N	Neutral	0.272
NPHS1	O60500-1.1	L732P	Neutral	0.057
NPHS1	O60500-1.1	L732Q	Neutral	0.171
NPHS1	O60500-1.1	L732R	Neutral	0.48
NPHS1	O60500-1.1	L732S	Neutral	0.292
NPHS1	O60500-1.1	L732T	Neutral	0.199
NPHS1	O60500-1.1	L732V	Neutral	0.091
NPHS1	O60500-1.1	L732W	Neutral	0.05
NPHS1	O60500-1.1	L732Y	Neutral	0.059
NPHS1	O60500-1.1	R733A	Pathogenic	0.768
NPHS1	O60500-1.1	R733C	Pathogenic	0.721
NPHS1	O60500-1.1	R733D	Neutral	0.202
NPHS1	O60500-1.1	R733E	Neutral	0.309
NPHS1	O60500-1.1	R733F	Pathogenic	0.73
NPHS1	O60500-1.1	R733G	Pathogenic	0.687
NPHS1	O60500-1.1	R733H	Pathogenic	0.532
NPHS1	O60500-1.1	R733I	Pathogenic	0.782
NPHS1	O60500-1.1	R733K	Neutral	0.242
NPHS1	O60500-1.1	R733L	Pathogenic	0.821
NPHS1	O60500-1.1	R733M	Pathogenic	0.773
NPHS1	O60500-1.1	R733N	Neutral	0.391
NPHS1	O60500-1.1	R733P	Pathogenic	0.703
NPHS1	O60500-1.1	R733Q	Pathogenic	0.525
NPHS1	O60500-1.1	R733S	Pathogenic	0.632
NPHS1	O60500-1.1	R733T	Pathogenic	0.624
NPHS1	O60500-1.1	R733V	Pathogenic	0.701
NPHS1	O60500-1.1	R733W	Pathogenic	0.849
NPHS1	O60500-1.1	R733Y	Pathogenic	0.505
NPHS1	O60500-1.1	L734A	Pathogenic	0.997
NPHS1	O60500-1.1	L734C	Pathogenic	0.989
NPHS1	O60500-1.1	L734D	Pathogenic	0.997
NPHS1	O60500-1.1	L734E	Pathogenic	0.996
NPHS1	O60500-1.1	L734F	Pathogenic	0.966
NPHS1	O60500-1.1	L734G	Pathogenic	0.997
NPHS1	O60500-1.1	L734H	Pathogenic	0.986
NPHS1	O60500-1.1	L734I	Pathogenic	0.98
NPHS1	O60500-1.1	L734K	Pathogenic	0.998
NPHS1	O60500-1.1	L734M	Pathogenic	0.989
NPHS1	O60500-1.1	L734N	Pathogenic	0.997
NPHS1	O60500-1.1	L734P	Pathogenic	0.982
NPHS1	O60500-1.1	L734Q	Pathogenic	0.995
NPHS1	O60500-1.1	L734R	Pathogenic	0.999
NPHS1	O60500-1.1	L734S	Pathogenic	0.997
NPHS1	O60500-1.1	L734T	Pathogenic	0.996
NPHS1	O60500-1.1	L734V	Pathogenic	0.989
NPHS1	O60500-1.1	L734W	Pathogenic	0.98
NPHS1	O60500-1.1	L734Y	Pathogenic	0.983
NPHS1	O60500-1.1	D735A	Pathogenic	0.976
NPHS1	O60500-1.1	D735C	Pathogenic	0.979
NPHS1	O60500-1.1	D735E	Pathogenic	0.977
NPHS1	O60500-1.1	D735F	Pathogenic	0.997
NPHS1	O60500-1.1	D735G	Pathogenic	0.984
NPHS1	O60500-1.1	D735H	Pathogenic	0.981
NPHS1	O60500-1.1	D735I	Pathogenic	0.997
NPHS1	O60500-1.1	D735K	Pathogenic	0.965
NPHS1	O60500-1.1	D735L	Pathogenic	0.994
NPHS1	O60500-1.1	D735M	Pathogenic	0.993
NPHS1	O60500-1.1	D735N	Pathogenic	0.957
NPHS1	O60500-1.1	D735P	Pathogenic	0.985
NPHS1	O60500-1.1	D735Q	Pathogenic	0.976
NPHS1	O60500-1.1	D735R	Pathogenic	0.962
NPHS1	O60500-1.1	D735S	Pathogenic	0.979
NPHS1	O60500-1.1	D735T	Pathogenic	0.971
NPHS1	O60500-1.1	D735V	Pathogenic	0.988
NPHS1	O60500-1.1	D735W	Pathogenic	0.999
NPHS1	O60500-1.1	D735Y	Pathogenic	0.993
NPHS1	O60500-1.1	V736A	Pathogenic	0.979
NPHS1	O60500-1.1	V736C	Pathogenic	0.88
NPHS1	O60500-1.1	V736D	Pathogenic	0.975
NPHS1	O60500-1.1	V736E	Pathogenic	0.975
NPHS1	O60500-1.1	V736F	Pathogenic	0.94
NPHS1	O60500-1.1	V736G	Pathogenic	0.972
NPHS1	O60500-1.1	V736H	Pathogenic	0.91
NPHS1	O60500-1.1	V736I	Pathogenic	0.984
NPHS1	O60500-1.1	V736K	Pathogenic	0.992
NPHS1	O60500-1.1	V736L	Pathogenic	0.959
NPHS1	O60500-1.1	V736M	Pathogenic	0.922
NPHS1	O60500-1.1	V736N	Pathogenic	0.965
NPHS1	O60500-1.1	V736P	Pathogenic	0.869
NPHS1	O60500-1.1	V736Q	Pathogenic	0.959
NPHS1	O60500-1.1	V736R	Pathogenic	0.991
NPHS1	O60500-1.1	V736S	Pathogenic	0.968
NPHS1	O60500-1.1	V736T	Pathogenic	0.965
NPHS1	O60500-1.1	V736W	Pathogenic	0.965
NPHS1	O60500-1.1	V736Y	Pathogenic	0.919
NPHS1	O60500-1.1	H737A	Pathogenic	0.89
NPHS1	O60500-1.1	H737C	Pathogenic	0.904
NPHS1	O60500-1.1	H737D	Pathogenic	0.953
NPHS1	O60500-1.1	H737E	Pathogenic	0.942
NPHS1	O60500-1.1	H737F	Pathogenic	0.98
NPHS1	O60500-1.1	H737G	Pathogenic	0.922
NPHS1	O60500-1.1	H737I	Pathogenic	0.946
NPHS1	O60500-1.1	H737K	Pathogenic	0.957
NPHS1	O60500-1.1	H737L	Pathogenic	0.937
NPHS1	O60500-1.1	H737M	Pathogenic	0.917
NPHS1	O60500-1.1	H737N	Pathogenic	0.969
NPHS1	O60500-1.1	H737P	Pathogenic	0.897
NPHS1	O60500-1.1	H737Q	Pathogenic	0.885
NPHS1	O60500-1.1	H737R	Pathogenic	0.979
NPHS1	O60500-1.1	H737S	Pathogenic	0.912
NPHS1	O60500-1.1	H737T	Pathogenic	0.802
NPHS1	O60500-1.1	H737V	Pathogenic	0.895
NPHS1	O60500-1.1	H737W	Pathogenic	0.992
NPHS1	O60500-1.1	H737Y	Pathogenic	0.982
NPHS1	O60500-1.1	Y738A	Pathogenic	0.996
NPHS1	O60500-1.1	Y738C	Pathogenic	0.984
NPHS1	O60500-1.1	Y738D	Pathogenic	0.998
NPHS1	O60500-1.1	Y738E	Pathogenic	0.997
NPHS1	O60500-1.1	Y738F	Pathogenic	0.998
NPHS1	O60500-1.1	Y738G	Pathogenic	0.998
NPHS1	O60500-1.1	Y738H	Pathogenic	0.998
NPHS1	O60500-1.1	Y738I	Pathogenic	0.992
NPHS1	O60500-1.1	Y738K	Pathogenic	0.997
NPHS1	O60500-1.1	Y738L	Pathogenic	0.991
NPHS1	O60500-1.1	Y738M	Pathogenic	0.982
NPHS1	O60500-1.1	Y738N	Pathogenic	0.998
NPHS1	O60500-1.1	Y738P	Pathogenic	0.981
NPHS1	O60500-1.1	Y738Q	Pathogenic	0.996
NPHS1	O60500-1.1	Y738R	Pathogenic	0.997
NPHS1	O60500-1.1	Y738S	Pathogenic	0.997
NPHS1	O60500-1.1	Y738T	Pathogenic	0.993
NPHS1	O60500-1.1	Y738V	Pathogenic	0.988
NPHS1	O60500-1.1	Y738W	Pathogenic	0.999
NPHS1	O60500-1.1	A739C	Pathogenic	0.865
NPHS1	O60500-1.1	A739D	Pathogenic	0.855
NPHS1	O60500-1.1	A739E	Pathogenic	0.917
NPHS1	O60500-1.1	A739F	Pathogenic	0.968
NPHS1	O60500-1.1	A739G	Pathogenic	0.788
NPHS1	O60500-1.1	A739H	Pathogenic	0.745
NPHS1	O60500-1.1	A739I	Pathogenic	0.973
NPHS1	O60500-1.1	A739K	Pathogenic	0.972
NPHS1	O60500-1.1	A739L	Pathogenic	0.969
NPHS1	O60500-1.1	A739M	Pathogenic	0.939
NPHS1	O60500-1.1	A739N	Pathogenic	0.838
NPHS1	O60500-1.1	A739P	Pathogenic	0.762
NPHS1	O60500-1.1	A739Q	Pathogenic	0.87
NPHS1	O60500-1.1	A739R	Pathogenic	0.98
NPHS1	O60500-1.1	A739S	Pathogenic	0.812
NPHS1	O60500-1.1	A739T	Pathogenic	0.75
NPHS1	O60500-1.1	A739V	Pathogenic	0.934
NPHS1	O60500-1.1	A739W	Pathogenic	0.987
NPHS1	O60500-1.1	A739Y	Pathogenic	0.911
NPHS1	O60500-1.1	P740A	Pathogenic	0.937
NPHS1	O60500-1.1	P740C	Pathogenic	0.773
NPHS1	O60500-1.1	P740D	Pathogenic	0.978
NPHS1	O60500-1.1	P740E	Pathogenic	0.982
NPHS1	O60500-1.1	P740F	Pathogenic	0.952
NPHS1	O60500-1.1	P740G	Pathogenic	0.961
NPHS1	O60500-1.1	P740H	Pathogenic	0.936
NPHS1	O60500-1.1	P740I	Pathogenic	0.959
NPHS1	O60500-1.1	P740K	Pathogenic	0.994
NPHS1	O60500-1.1	P740L	Pathogenic	0.953
NPHS1	O60500-1.1	P740M	Pathogenic	0.937
NPHS1	O60500-1.1	P740N	Pathogenic	0.963
NPHS1	O60500-1.1	P740Q	Pathogenic	0.971
NPHS1	O60500-1.1	P740R	Pathogenic	0.994
NPHS1	O60500-1.1	P740S	Pathogenic	0.955
NPHS1	O60500-1.1	P740T	Pathogenic	0.909
NPHS1	O60500-1.1	P740V	Pathogenic	0.903
NPHS1	O60500-1.1	P740W	Pathogenic	0.987
NPHS1	O60500-1.1	P740Y	Pathogenic	0.909
NPHS1	O60500-1.1	T741A	Neutral	0.08
NPHS1	O60500-1.1	T741C	Neutral	0.093
NPHS1	O60500-1.1	T741D	Neutral	0.124
NPHS1	O60500-1.1	T741E	Neutral	0.14
NPHS1	O60500-1.1	T741F	Neutral	0.342
NPHS1	O60500-1.1	T741G	Neutral	0.077
NPHS1	O60500-1.1	T741H	Neutral	0.041
NPHS1	O60500-1.1	T741I	Neutral	0.379
NPHS1	O60500-1.1	T741K	Neutral	0.336
NPHS1	O60500-1.1	T741L	Neutral	0.344
NPHS1	O60500-1.1	T741M	Neutral	0.207
NPHS1	O60500-1.1	T741N	Neutral	0.144
NPHS1	O60500-1.1	T741P	Neutral	0.059
NPHS1	O60500-1.1	T741Q	Neutral	0.089
NPHS1	O60500-1.1	T741R	Neutral	0.413
NPHS1	O60500-1.1	T741S	Neutral	0.139
NPHS1	O60500-1.1	T741V	Neutral	0.195
NPHS1	O60500-1.1	T741W	Pathogenic	0.667
NPHS1	O60500-1.1	T741Y	Neutral	0.148
NPHS1	O60500-1.1	I742A	Pathogenic	0.996
NPHS1	O60500-1.1	I742C	Pathogenic	0.982
NPHS1	O60500-1.1	I742D	Pathogenic	0.997
NPHS1	O60500-1.1	I742E	Pathogenic	0.994
NPHS1	O60500-1.1	I742F	Pathogenic	0.929
NPHS1	O60500-1.1	I742G	Pathogenic	0.994
NPHS1	O60500-1.1	I742H	Pathogenic	0.976
NPHS1	O60500-1.1	I742K	Pathogenic	0.996
NPHS1	O60500-1.1	I742L	Pathogenic	0.962
NPHS1	O60500-1.1	I742M	Pathogenic	0.972
NPHS1	O60500-1.1	I742N	Pathogenic	0.995
NPHS1	O60500-1.1	I742P	Pathogenic	0.971
NPHS1	O60500-1.1	I742Q	Pathogenic	0.987
NPHS1	O60500-1.1	I742R	Pathogenic	0.997
NPHS1	O60500-1.1	I742S	Pathogenic	0.996
NPHS1	O60500-1.1	I742T	Pathogenic	0.993
NPHS1	O60500-1.1	I742V	Pathogenic	0.992
NPHS1	O60500-1.1	I742W	Pathogenic	0.935
NPHS1	O60500-1.1	I742Y	Pathogenic	0.972
NPHS1	O60500-1.1	R743A	Pathogenic	0.992
NPHS1	O60500-1.1	R743C	Pathogenic	0.99
NPHS1	O60500-1.1	R743D	Pathogenic	0.908
NPHS1	O60500-1.1	R743E	Pathogenic	0.946
NPHS1	O60500-1.1	R743F	Pathogenic	0.991
NPHS1	O60500-1.1	R743G	Pathogenic	0.988
NPHS1	O60500-1.1	R743H	Pathogenic	0.978
NPHS1	O60500-1.1	R743I	Pathogenic	0.993
NPHS1	O60500-1.1	R743K	Pathogenic	0.925
NPHS1	O60500-1.1	R743L	Pathogenic	0.994
NPHS1	O60500-1.1	R743M	Pathogenic	0.992
NPHS1	O60500-1.1	R743N	Pathogenic	0.962
NPHS1	O60500-1.1	R743P	Pathogenic	0.989
NPHS1	O60500-1.1	R743Q	Pathogenic	0.977
NPHS1	O60500-1.1	R743S	Pathogenic	0.985
NPHS1	O60500-1.1	R743T	Pathogenic	0.985
NPHS1	O60500-1.1	R743V	Pathogenic	0.989
NPHS1	O60500-1.1	R743W	Pathogenic	0.995
NPHS1	O60500-1.1	R743Y	Pathogenic	0.975
NPHS1	O60500-1.1	A744C	Neutral	0.138
NPHS1	O60500-1.1	A744D	Neutral	0.129
NPHS1	O60500-1.1	A744E	Neutral	0.217
NPHS1	O60500-1.1	A744F	Neutral	0.432
NPHS1	O60500-1.1	A744G	Neutral	0.085
NPHS1	O60500-1.1	A744H	Neutral	0.068
NPHS1	O60500-1.1	A744I	Neutral	0.472
NPHS1	O60500-1.1	A744K	Neutral	0.463
NPHS1	O60500-1.1	A744L	Neutral	0.434
NPHS1	O60500-1.1	A744M	Neutral	0.276
NPHS1	O60500-1.1	A744N	Neutral	0.114
NPHS1	O60500-1.1	A744P	Neutral	0.074
NPHS1	O60500-1.1	A744Q	Neutral	0.143
NPHS1	O60500-1.1	A744R	Pathogenic	0.545
NPHS1	O60500-1.1	A744S	Neutral	0.097
NPHS1	O60500-1.1	A744T	Neutral	0.069
NPHS1	O60500-1.1	A744V	Neutral	0.262
NPHS1	O60500-1.1	A744W	Pathogenic	0.663
NPHS1	O60500-1.1	A744Y	Neutral	0.203
NPHS1	O60500-1.1	L745A	Pathogenic	0.9
NPHS1	O60500-1.1	L745C	Pathogenic	0.679
NPHS1	O60500-1.1	L745D	Pathogenic	0.885
NPHS1	O60500-1.1	L745E	Pathogenic	0.86
NPHS1	O60500-1.1	L745F	Neutral	0.395
NPHS1	O60500-1.1	L745G	Pathogenic	0.871
NPHS1	O60500-1.1	L745H	Pathogenic	0.613
NPHS1	O60500-1.1	L745I	Pathogenic	0.533
NPHS1	O60500-1.1	L745K	Pathogenic	0.934
NPHS1	O60500-1.1	L745M	Pathogenic	0.664
NPHS1	O60500-1.1	L745N	Pathogenic	0.888
NPHS1	O60500-1.1	L745P	Pathogenic	0.562
NPHS1	O60500-1.1	L745Q	Pathogenic	0.814
NPHS1	O60500-1.1	L745R	Pathogenic	0.951
NPHS1	O60500-1.1	L745S	Pathogenic	0.898
NPHS1	O60500-1.1	L745T	Pathogenic	0.841
NPHS1	O60500-1.1	L745V	Pathogenic	0.679
NPHS1	O60500-1.1	L745W	Pathogenic	0.53
NPHS1	O60500-1.1	L745Y	Pathogenic	0.571
NPHS1	O60500-1.1	Q746A	Neutral	0.09
NPHS1	O60500-1.1	Q746C	Neutral	0.072
NPHS1	O60500-1.1	Q746D	Neutral	0.08
NPHS1	O60500-1.1	Q746E	Neutral	0.094
NPHS1	O60500-1.1	Q746F	Neutral	0.179
NPHS1	O60500-1.1	Q746G	Neutral	0.062
NPHS1	O60500-1.1	Q746H	Neutral	0.039
NPHS1	O60500-1.1	Q746I	Neutral	0.147
NPHS1	O60500-1.1	Q746K	Neutral	0.146
NPHS1	O60500-1.1	Q746L	Neutral	0.18
NPHS1	O60500-1.1	Q746M	Neutral	0.196
NPHS1	O60500-1.1	Q746N	Neutral	0.056
NPHS1	O60500-1.1	Q746P	Neutral	0.096
NPHS1	O60500-1.1	Q746R	Neutral	0.192
NPHS1	O60500-1.1	Q746S	Neutral	0.071
NPHS1	O60500-1.1	Q746T	Neutral	0.047
NPHS1	O60500-1.1	Q746V	Neutral	0.095
NPHS1	O60500-1.1	Q746W	Pathogenic	0.556
NPHS1	O60500-1.1	Q746Y	Neutral	0.14
NPHS1	O60500-1.1	D747A	Pathogenic	0.979
NPHS1	O60500-1.1	D747C	Pathogenic	0.982
NPHS1	O60500-1.1	D747E	Pathogenic	0.98
NPHS1	O60500-1.1	D747F	Pathogenic	0.998
NPHS1	O60500-1.1	D747G	Pathogenic	0.985
NPHS1	O60500-1.1	D747H	Pathogenic	0.983
NPHS1	O60500-1.1	D747I	Pathogenic	0.997
NPHS1	O60500-1.1	D747K	Pathogenic	0.968
NPHS1	O60500-1.1	D747L	Pathogenic	0.995
NPHS1	O60500-1.1	D747M	Pathogenic	0.993
NPHS1	O60500-1.1	D747N	Pathogenic	0.962
NPHS1	O60500-1.1	D747P	Pathogenic	0.986
NPHS1	O60500-1.1	D747Q	Pathogenic	0.978
NPHS1	O60500-1.1	D747R	Pathogenic	0.966
NPHS1	O60500-1.1	D747S	Pathogenic	0.981
NPHS1	O60500-1.1	D747T	Pathogenic	0.974
NPHS1	O60500-1.1	D747V	Pathogenic	0.989
NPHS1	O60500-1.1	D747W	Pathogenic	0.999
NPHS1	O60500-1.1	D747Y	Pathogenic	0.993
NPHS1	O60500-1.1	P748A	Pathogenic	0.884
NPHS1	O60500-1.1	P748C	Pathogenic	0.637
NPHS1	O60500-1.1	P748D	Pathogenic	0.957
NPHS1	O60500-1.1	P748E	Pathogenic	0.966
NPHS1	O60500-1.1	P748F	Pathogenic	0.911
NPHS1	O60500-1.1	P748G	Pathogenic	0.927
NPHS1	O60500-1.1	P748H	Pathogenic	0.882
NPHS1	O60500-1.1	P748I	Pathogenic	0.924
NPHS1	O60500-1.1	P748K	Pathogenic	0.989
NPHS1	O60500-1.1	P748L	Pathogenic	0.912
NPHS1	O60500-1.1	P748M	Pathogenic	0.885
NPHS1	O60500-1.1	P748N	Pathogenic	0.929
NPHS1	O60500-1.1	P748Q	Pathogenic	0.945
NPHS1	O60500-1.1	P748R	Pathogenic	0.988
NPHS1	O60500-1.1	P748S	Pathogenic	0.917
NPHS1	O60500-1.1	P748T	Pathogenic	0.836
NPHS1	O60500-1.1	P748V	Pathogenic	0.828
NPHS1	O60500-1.1	P748W	Pathogenic	0.975
NPHS1	O60500-1.1	P748Y	Pathogenic	0.837
NPHS1	O60500-1.1	T749A	Pathogenic	0.758
NPHS1	O60500-1.1	T749C	Pathogenic	0.785
NPHS1	O60500-1.1	T749D	Pathogenic	0.836
NPHS1	O60500-1.1	T749E	Pathogenic	0.853
NPHS1	O60500-1.1	T749F	Pathogenic	0.949
NPHS1	O60500-1.1	T749G	Pathogenic	0.75
NPHS1	O60500-1.1	T749H	Pathogenic	0.605
NPHS1	O60500-1.1	T749I	Pathogenic	0.956
NPHS1	O60500-1.1	T749K	Pathogenic	0.948
NPHS1	O60500-1.1	T749L	Pathogenic	0.949
NPHS1	O60500-1.1	T749M	Pathogenic	0.903
NPHS1	O60500-1.1	T749N	Pathogenic	0.858
NPHS1	O60500-1.1	T749P	Pathogenic	0.692
NPHS1	O60500-1.1	T749Q	Pathogenic	0.778
NPHS1	O60500-1.1	T749R	Pathogenic	0.962
NPHS1	O60500-1.1	T749S	Pathogenic	0.853
NPHS1	O60500-1.1	T749V	Pathogenic	0.897
NPHS1	O60500-1.1	T749W	Pathogenic	0.986
NPHS1	O60500-1.1	T749Y	Pathogenic	0.862
NPHS1	O60500-1.1	E750A	Pathogenic	0.722
NPHS1	O60500-1.1	E750C	Pathogenic	0.577
NPHS1	O60500-1.1	E750D	Pathogenic	0.593
NPHS1	O60500-1.1	E750F	Pathogenic	0.879
NPHS1	O60500-1.1	E750G	Pathogenic	0.633
NPHS1	O60500-1.1	E750H	Pathogenic	0.578
NPHS1	O60500-1.1	E750I	Pathogenic	0.851
NPHS1	O60500-1.1	E750K	Pathogenic	0.621
NPHS1	O60500-1.1	E750L	Pathogenic	0.831
NPHS1	O60500-1.1	E750M	Pathogenic	0.785
NPHS1	O60500-1.1	E750N	Neutral	0.336
NPHS1	O60500-1.1	E750P	Pathogenic	0.736
NPHS1	O60500-1.1	E750Q	Pathogenic	0.621
NPHS1	O60500-1.1	E750R	Pathogenic	0.604
NPHS1	O60500-1.1	E750S	Pathogenic	0.668
NPHS1	O60500-1.1	E750T	Pathogenic	0.566
NPHS1	O60500-1.1	E750V	Pathogenic	0.733
NPHS1	O60500-1.1	E750W	Pathogenic	0.965
NPHS1	O60500-1.1	E750Y	Pathogenic	0.784
NPHS1	O60500-1.1	V751A	Pathogenic	0.992
NPHS1	O60500-1.1	V751C	Pathogenic	0.951
NPHS1	O60500-1.1	V751D	Pathogenic	0.991
NPHS1	O60500-1.1	V751E	Pathogenic	0.99
NPHS1	O60500-1.1	V751F	Pathogenic	0.976
NPHS1	O60500-1.1	V751G	Pathogenic	0.989
NPHS1	O60500-1.1	V751H	Pathogenic	0.964
NPHS1	O60500-1.1	V751I	Pathogenic	0.994
NPHS1	O60500-1.1	V751K	Pathogenic	0.997
NPHS1	O60500-1.1	V751L	Pathogenic	0.984
NPHS1	O60500-1.1	V751M	Pathogenic	0.969
NPHS1	O60500-1.1	V751N	Pathogenic	0.986
NPHS1	O60500-1.1	V751P	Pathogenic	0.946
NPHS1	O60500-1.1	V751Q	Pathogenic	0.984
NPHS1	O60500-1.1	V751R	Pathogenic	0.997
NPHS1	O60500-1.1	V751S	Pathogenic	0.988
NPHS1	O60500-1.1	V751T	Pathogenic	0.986
NPHS1	O60500-1.1	V751W	Pathogenic	0.986
NPHS1	O60500-1.1	V751Y	Pathogenic	0.968
NPHS1	O60500-1.1	N752A	Pathogenic	0.671
NPHS1	O60500-1.1	N752C	Pathogenic	0.704
NPHS1	O60500-1.1	N752D	Pathogenic	0.56
NPHS1	O60500-1.1	N752E	Neutral	0.459
NPHS1	O60500-1.1	N752F	Pathogenic	0.94
NPHS1	O60500-1.1	N752G	Pathogenic	0.818
NPHS1	O60500-1.1	N752H	Pathogenic	0.815
NPHS1	O60500-1.1	N752I	Pathogenic	0.925
NPHS1	O60500-1.1	N752K	Pathogenic	0.726
NPHS1	O60500-1.1	N752L	Pathogenic	0.914
NPHS1	O60500-1.1	N752M	Pathogenic	0.887
NPHS1	O60500-1.1	N752P	Pathogenic	0.685
NPHS1	O60500-1.1	N752Q	Pathogenic	0.614
NPHS1	O60500-1.1	N752R	Pathogenic	0.786
NPHS1	O60500-1.1	N752S	Pathogenic	0.778
NPHS1	O60500-1.1	N752T	Pathogenic	0.694
NPHS1	O60500-1.1	N752V	Pathogenic	0.767
NPHS1	O60500-1.1	N752W	Pathogenic	0.976
NPHS1	O60500-1.1	N752Y	Pathogenic	0.887
NPHS1	O60500-1.1	V753A	Neutral	0.204
NPHS1	O60500-1.1	V753C	Neutral	0.039
NPHS1	O60500-1.1	V753D	Neutral	0.179
NPHS1	O60500-1.1	V753E	Neutral	0.174
NPHS1	O60500-1.1	V753F	Neutral	0.079
NPHS1	O60500-1.1	V753G	Neutral	0.161
NPHS1	O60500-1.1	V753H	Neutral	0.053
NPHS1	O60500-1.1	V753I	Neutral	0.252
NPHS1	O60500-1.1	V753K	Neutral	0.397
NPHS1	O60500-1.1	V753L	Neutral	0.115
NPHS1	O60500-1.1	V753M	Neutral	0.061
NPHS1	O60500-1.1	V753N	Neutral	0.131
NPHS1	O60500-1.1	V753P	Neutral	0.035
NPHS1	O60500-1.1	V753Q	Neutral	0.113
NPHS1	O60500-1.1	V753R	Neutral	0.38
NPHS1	O60500-1.1	V753S	Neutral	0.143
NPHS1	O60500-1.1	V753T	Neutral	0.13
NPHS1	O60500-1.1	V753W	Neutral	0.13
NPHS1	O60500-1.1	V753Y	Neutral	0.059
NPHS1	O60500-1.1	G754A	Pathogenic	0.971
NPHS1	O60500-1.1	G754C	Pathogenic	0.978
NPHS1	O60500-1.1	G754D	Pathogenic	0.988
NPHS1	O60500-1.1	G754E	Pathogenic	0.985
NPHS1	O60500-1.1	G754F	Pathogenic	0.998
NPHS1	O60500-1.1	G754H	Pathogenic	0.975
NPHS1	O60500-1.1	G754I	Pathogenic	0.996
NPHS1	O60500-1.1	G754K	Pathogenic	0.995
NPHS1	O60500-1.1	G754L	Pathogenic	0.995
NPHS1	O60500-1.1	G754M	Pathogenic	0.994
NPHS1	O60500-1.1	G754N	Pathogenic	0.99
NPHS1	O60500-1.1	G754P	Pathogenic	0.98
NPHS1	O60500-1.1	G754Q	Pathogenic	0.976
NPHS1	O60500-1.1	G754R	Pathogenic	0.997
NPHS1	O60500-1.1	G754S	Pathogenic	0.963
NPHS1	O60500-1.1	G754T	Pathogenic	0.963
NPHS1	O60500-1.1	G754V	Pathogenic	0.99
NPHS1	O60500-1.1	G754W	Pathogenic	1.0
NPHS1	O60500-1.1	G754Y	Pathogenic	0.994
NPHS1	O60500-1.1	G755A	Neutral	0.397
NPHS1	O60500-1.1	G755C	Neutral	0.459
NPHS1	O60500-1.1	G755D	Pathogenic	0.607
NPHS1	O60500-1.1	G755E	Pathogenic	0.566
NPHS1	O60500-1.1	G755F	Pathogenic	0.9
NPHS1	O60500-1.1	G755H	Neutral	0.432
NPHS1	O60500-1.1	G755I	Pathogenic	0.826
NPHS1	O60500-1.1	G755K	Pathogenic	0.803
NPHS1	O60500-1.1	G755L	Pathogenic	0.802
NPHS1	O60500-1.1	G755M	Pathogenic	0.751
NPHS1	O60500-1.1	G755N	Pathogenic	0.669
NPHS1	O60500-1.1	G755P	Neutral	0.484
NPHS1	O60500-1.1	G755Q	Neutral	0.441
NPHS1	O60500-1.1	G755R	Pathogenic	0.85
NPHS1	O60500-1.1	G755S	Neutral	0.336
NPHS1	O60500-1.1	G755T	Neutral	0.336
NPHS1	O60500-1.1	G755V	Pathogenic	0.653
NPHS1	O60500-1.1	G755W	Pathogenic	0.981
NPHS1	O60500-1.1	G755Y	Pathogenic	0.75
NPHS1	O60500-1.1	S756A	Neutral	0.315
NPHS1	O60500-1.1	S756C	Neutral	0.399
NPHS1	O60500-1.1	S756D	Neutral	0.421
NPHS1	O60500-1.1	S756E	Neutral	0.478
NPHS1	O60500-1.1	S756F	Pathogenic	0.825
NPHS1	O60500-1.1	S756G	Neutral	0.234
NPHS1	O60500-1.1	S756H	Neutral	0.285
NPHS1	O60500-1.1	S756I	Pathogenic	0.788
NPHS1	O60500-1.1	S756K	Pathogenic	0.741
NPHS1	O60500-1.1	S756L	Pathogenic	0.761
NPHS1	O60500-1.1	S756M	Pathogenic	0.703
NPHS1	O60500-1.1	S756N	Neutral	0.488
NPHS1	O60500-1.1	S756P	Neutral	0.33
NPHS1	O60500-1.1	S756Q	Neutral	0.356
NPHS1	O60500-1.1	S756R	Pathogenic	0.727
NPHS1	O60500-1.1	S756T	Neutral	0.372
NPHS1	O60500-1.1	S756V	Neutral	0.497
NPHS1	O60500-1.1	S756W	Pathogenic	0.924
NPHS1	O60500-1.1	S756Y	Pathogenic	0.613
NPHS1	O60500-1.1	V757A	Pathogenic	0.835
NPHS1	O60500-1.1	V757C	Neutral	0.443
NPHS1	O60500-1.1	V757D	Pathogenic	0.812
NPHS1	O60500-1.1	V757E	Pathogenic	0.807
NPHS1	O60500-1.1	V757F	Pathogenic	0.63
NPHS1	O60500-1.1	V757G	Pathogenic	0.791
NPHS1	O60500-1.1	V757H	Pathogenic	0.524
NPHS1	O60500-1.1	V757I	Pathogenic	0.869
NPHS1	O60500-1.1	V757K	Pathogenic	0.929
NPHS1	O60500-1.1	V757L	Pathogenic	0.719
NPHS1	O60500-1.1	V757M	Pathogenic	0.56
NPHS1	O60500-1.1	V757N	Pathogenic	0.749
NPHS1	O60500-1.1	V757P	Neutral	0.418
NPHS1	O60500-1.1	V757Q	Pathogenic	0.716
NPHS1	O60500-1.1	V757R	Pathogenic	0.924
NPHS1	O60500-1.1	V757S	Pathogenic	0.768
NPHS1	O60500-1.1	V757T	Pathogenic	0.747
NPHS1	O60500-1.1	V757W	Pathogenic	0.747
NPHS1	O60500-1.1	V757Y	Pathogenic	0.551
NPHS1	O60500-1.1	D758A	Pathogenic	0.87
NPHS1	O60500-1.1	D758C	Pathogenic	0.887
NPHS1	O60500-1.1	D758E	Pathogenic	0.876
NPHS1	O60500-1.1	D758F	Pathogenic	0.985
NPHS1	O60500-1.1	D758G	Pathogenic	0.908
NPHS1	O60500-1.1	D758H	Pathogenic	0.892
NPHS1	O60500-1.1	D758I	Pathogenic	0.981
NPHS1	O60500-1.1	D758K	Pathogenic	0.817
NPHS1	O60500-1.1	D758L	Pathogenic	0.967
NPHS1	O60500-1.1	D758M	Pathogenic	0.957
NPHS1	O60500-1.1	D758N	Pathogenic	0.786
NPHS1	O60500-1.1	D758P	Pathogenic	0.915
NPHS1	O60500-1.1	D758Q	Pathogenic	0.869
NPHS1	O60500-1.1	D758R	Pathogenic	0.807
NPHS1	O60500-1.1	D758S	Pathogenic	0.886
NPHS1	O60500-1.1	D758T	Pathogenic	0.846
NPHS1	O60500-1.1	D758V	Pathogenic	0.932
NPHS1	O60500-1.1	D758W	Pathogenic	0.994
NPHS1	O60500-1.1	D758Y	Pathogenic	0.956
NPHS1	O60500-1.1	I759A	Pathogenic	0.98
NPHS1	O60500-1.1	I759C	Pathogenic	0.921
NPHS1	O60500-1.1	I759D	Pathogenic	0.984
NPHS1	O60500-1.1	I759E	Pathogenic	0.971
NPHS1	O60500-1.1	I759F	Pathogenic	0.735
NPHS1	O60500-1.1	I759G	Pathogenic	0.974
NPHS1	O60500-1.1	I759H	Pathogenic	0.897
NPHS1	O60500-1.1	I759K	Pathogenic	0.981
NPHS1	O60500-1.1	I759L	Pathogenic	0.844
NPHS1	O60500-1.1	I759M	Pathogenic	0.879
NPHS1	O60500-1.1	I759N	Pathogenic	0.978
NPHS1	O60500-1.1	I759P	Pathogenic	0.876
NPHS1	O60500-1.1	I759Q	Pathogenic	0.942
NPHS1	O60500-1.1	I759R	Pathogenic	0.986
NPHS1	O60500-1.1	I759S	Pathogenic	0.98
NPHS1	O60500-1.1	I759T	Pathogenic	0.967
NPHS1	O60500-1.1	I759V	Pathogenic	0.963
NPHS1	O60500-1.1	I759W	Pathogenic	0.755
NPHS1	O60500-1.1	I759Y	Pathogenic	0.88
NPHS1	O60500-1.1	V760A	Pathogenic	0.705
NPHS1	O60500-1.1	V760C	Neutral	0.273
NPHS1	O60500-1.1	V760D	Pathogenic	0.67
NPHS1	O60500-1.1	V760E	Pathogenic	0.663
NPHS1	O60500-1.1	V760F	Neutral	0.445
NPHS1	O60500-1.1	V760G	Pathogenic	0.641
NPHS1	O60500-1.1	V760H	Neutral	0.341
NPHS1	O60500-1.1	V760I	Pathogenic	0.758
NPHS1	O60500-1.1	V760K	Pathogenic	0.86
NPHS1	O60500-1.1	V760L	Pathogenic	0.547
NPHS1	O60500-1.1	V760M	Neutral	0.375
NPHS1	O60500-1.1	V760N	Pathogenic	0.584
NPHS1	O60500-1.1	V760P	Neutral	0.253
NPHS1	O60500-1.1	V760Q	Pathogenic	0.543
NPHS1	O60500-1.1	V760R	Pathogenic	0.851
NPHS1	O60500-1.1	V760S	Pathogenic	0.609
NPHS1	O60500-1.1	V760T	Pathogenic	0.582
NPHS1	O60500-1.1	V760W	Pathogenic	0.582
NPHS1	O60500-1.1	V760Y	Neutral	0.366
NPHS1	O60500-1.1	C761A	Pathogenic	0.965
NPHS1	O60500-1.1	C761D	Pathogenic	0.967
NPHS1	O60500-1.1	C761E	Pathogenic	0.962
NPHS1	O60500-1.1	C761F	Pathogenic	0.968
NPHS1	O60500-1.1	C761G	Pathogenic	0.954
NPHS1	O60500-1.1	C761H	Pathogenic	0.936
NPHS1	O60500-1.1	C761I	Pathogenic	0.973
NPHS1	O60500-1.1	C761K	Pathogenic	0.991
NPHS1	O60500-1.1	C761L	Pathogenic	0.969
NPHS1	O60500-1.1	C761M	Pathogenic	0.939
NPHS1	O60500-1.1	C761N	Pathogenic	0.963
NPHS1	O60500-1.1	C761P	Pathogenic	0.76
NPHS1	O60500-1.1	C761Q	Pathogenic	0.957
NPHS1	O60500-1.1	C761R	Pathogenic	0.994
NPHS1	O60500-1.1	C761S	Pathogenic	0.964
NPHS1	O60500-1.1	C761T	Pathogenic	0.938
NPHS1	O60500-1.1	C761V	Pathogenic	0.906
NPHS1	O60500-1.1	C761W	Pathogenic	0.992
NPHS1	O60500-1.1	C761Y	Pathogenic	0.916
NPHS1	O60500-1.1	T762A	Neutral	0.302
NPHS1	O60500-1.1	T762C	Neutral	0.336
NPHS1	O60500-1.1	T762D	Neutral	0.412
NPHS1	O60500-1.1	T762E	Neutral	0.445
NPHS1	O60500-1.1	T762F	Pathogenic	0.72
NPHS1	O60500-1.1	T762G	Neutral	0.293
NPHS1	O60500-1.1	T762H	Neutral	0.175
NPHS1	O60500-1.1	T762I	Pathogenic	0.751
NPHS1	O60500-1.1	T762K	Pathogenic	0.715
NPHS1	O60500-1.1	T762L	Pathogenic	0.722
NPHS1	O60500-1.1	T762M	Pathogenic	0.563
NPHS1	O60500-1.1	T762N	Neutral	0.455
NPHS1	O60500-1.1	T762P	Neutral	0.237
NPHS1	O60500-1.1	T762Q	Neutral	0.327
NPHS1	O60500-1.1	T762R	Pathogenic	0.777
NPHS1	O60500-1.1	T762S	Neutral	0.445
NPHS1	O60500-1.1	T762V	Pathogenic	0.546
NPHS1	O60500-1.1	T762W	Pathogenic	0.908
NPHS1	O60500-1.1	T762Y	Neutral	0.463
NPHS1	O60500-1.1	V763A	Pathogenic	0.707
NPHS1	O60500-1.1	V763C	Neutral	0.275
NPHS1	O60500-1.1	V763D	Pathogenic	0.672
NPHS1	O60500-1.1	V763E	Pathogenic	0.665
NPHS1	O60500-1.1	V763F	Neutral	0.448
NPHS1	O60500-1.1	V763G	Pathogenic	0.643
NPHS1	O60500-1.1	V763H	Neutral	0.344
NPHS1	O60500-1.1	V763I	Pathogenic	0.76
NPHS1	O60500-1.1	V763K	Pathogenic	0.861
NPHS1	O60500-1.1	V763L	Pathogenic	0.55
NPHS1	O60500-1.1	V763M	Neutral	0.378
NPHS1	O60500-1.1	V763N	Pathogenic	0.586
NPHS1	O60500-1.1	V763P	Neutral	0.255
NPHS1	O60500-1.1	V763Q	Pathogenic	0.545
NPHS1	O60500-1.1	V763R	Pathogenic	0.852
NPHS1	O60500-1.1	V763S	Pathogenic	0.611
NPHS1	O60500-1.1	V763T	Pathogenic	0.585
NPHS1	O60500-1.1	V763W	Pathogenic	0.584
NPHS1	O60500-1.1	V763Y	Neutral	0.369
NPHS1	O60500-1.1	D764A	Pathogenic	0.988
NPHS1	O60500-1.1	D764C	Pathogenic	0.99
NPHS1	O60500-1.1	D764E	Pathogenic	0.988
NPHS1	O60500-1.1	D764F	Pathogenic	0.999
NPHS1	O60500-1.1	D764G	Pathogenic	0.992
NPHS1	O60500-1.1	D764H	Pathogenic	0.99
NPHS1	O60500-1.1	D764I	Pathogenic	0.998
NPHS1	O60500-1.1	D764K	Pathogenic	0.982
NPHS1	O60500-1.1	D764L	Pathogenic	0.997
NPHS1	O60500-1.1	D764M	Pathogenic	0.996
NPHS1	O60500-1.1	D764N	Pathogenic	0.978
NPHS1	O60500-1.1	D764P	Pathogenic	0.992
NPHS1	O60500-1.1	D764Q	Pathogenic	0.988
NPHS1	O60500-1.1	D764R	Pathogenic	0.98
NPHS1	O60500-1.1	D764S	Pathogenic	0.989
NPHS1	O60500-1.1	D764T	Pathogenic	0.985
NPHS1	O60500-1.1	D764V	Pathogenic	0.994
NPHS1	O60500-1.1	D764W	Pathogenic	1.0
NPHS1	O60500-1.1	D764Y	Pathogenic	0.996
NPHS1	O60500-1.1	A765C	Pathogenic	0.983
NPHS1	O60500-1.1	A765D	Pathogenic	0.981
NPHS1	O60500-1.1	A765E	Pathogenic	0.99
NPHS1	O60500-1.1	A765F	Pathogenic	0.996
NPHS1	O60500-1.1	A765G	Pathogenic	0.97
NPHS1	O60500-1.1	A765H	Pathogenic	0.963
NPHS1	O60500-1.1	A765I	Pathogenic	0.997
NPHS1	O60500-1.1	A765K	Pathogenic	0.997
NPHS1	O60500-1.1	A765L	Pathogenic	0.996
NPHS1	O60500-1.1	A765M	Pathogenic	0.993
NPHS1	O60500-1.1	A765N	Pathogenic	0.978
NPHS1	O60500-1.1	A765P	Pathogenic	0.966
NPHS1	O60500-1.1	A765Q	Pathogenic	0.983
NPHS1	O60500-1.1	A765R	Pathogenic	0.998
NPHS1	O60500-1.1	A765S	Pathogenic	0.974
NPHS1	O60500-1.1	A765T	Pathogenic	0.963
NPHS1	O60500-1.1	A765V	Pathogenic	0.992
NPHS1	O60500-1.1	A765W	Pathogenic	0.999
NPHS1	O60500-1.1	A765Y	Pathogenic	0.989
NPHS1	O60500-1.1	N766A	Pathogenic	0.989
NPHS1	O60500-1.1	N766C	Pathogenic	0.99
NPHS1	O60500-1.1	N766D	Pathogenic	0.982
NPHS1	O60500-1.1	N766E	Pathogenic	0.973
NPHS1	O60500-1.1	N766F	Pathogenic	0.999
NPHS1	O60500-1.1	N766G	Pathogenic	0.995
NPHS1	O60500-1.1	N766H	Pathogenic	0.995
NPHS1	O60500-1.1	N766I	Pathogenic	0.998
NPHS1	O60500-1.1	N766K	Pathogenic	0.991
NPHS1	O60500-1.1	N766L	Pathogenic	0.998
NPHS1	O60500-1.1	N766M	Pathogenic	0.997
NPHS1	O60500-1.1	N766P	Pathogenic	0.989
NPHS1	O60500-1.1	N766Q	Pathogenic	0.986
NPHS1	O60500-1.1	N766R	Pathogenic	0.994
NPHS1	O60500-1.1	N766S	Pathogenic	0.993
NPHS1	O60500-1.1	N766T	Pathogenic	0.99
NPHS1	O60500-1.1	N766V	Pathogenic	0.993
NPHS1	O60500-1.1	N766W	Pathogenic	0.999
NPHS1	O60500-1.1	N766Y	Pathogenic	0.997
NPHS1	O60500-1.1	P767A	Pathogenic	0.961
NPHS1	O60500-1.1	P767C	Pathogenic	0.851
NPHS1	O60500-1.1	P767D	Pathogenic	0.987
NPHS1	O60500-1.1	P767E	Pathogenic	0.989
NPHS1	O60500-1.1	P767F	Pathogenic	0.971
NPHS1	O60500-1.1	P767G	Pathogenic	0.976
NPHS1	O60500-1.1	P767H	Pathogenic	0.96
NPHS1	O60500-1.1	P767I	Pathogenic	0.975
NPHS1	O60500-1.1	P767K	Pathogenic	0.997
NPHS1	O60500-1.1	P767L	Pathogenic	0.971
NPHS1	O60500-1.1	P767M	Pathogenic	0.962
NPHS1	O60500-1.1	P767N	Pathogenic	0.977
NPHS1	O60500-1.1	P767Q	Pathogenic	0.982
NPHS1	O60500-1.1	P767R	Pathogenic	0.996
NPHS1	O60500-1.1	P767S	Pathogenic	0.973
NPHS1	O60500-1.1	P767T	Pathogenic	0.943
NPHS1	O60500-1.1	P767V	Pathogenic	0.94
NPHS1	O60500-1.1	P767W	Pathogenic	0.992
NPHS1	O60500-1.1	P767Y	Pathogenic	0.944
NPHS1	O60500-1.1	I768A	Pathogenic	0.94
NPHS1	O60500-1.1	I768C	Pathogenic	0.786
NPHS1	O60500-1.1	I768D	Pathogenic	0.952
NPHS1	O60500-1.1	I768E	Pathogenic	0.915
NPHS1	O60500-1.1	I768F	Neutral	0.466
NPHS1	O60500-1.1	I768G	Pathogenic	0.922
NPHS1	O60500-1.1	I768H	Pathogenic	0.734
NPHS1	O60500-1.1	I768K	Pathogenic	0.943
NPHS1	O60500-1.1	I768L	Pathogenic	0.631
NPHS1	O60500-1.1	I768M	Pathogenic	0.697
NPHS1	O60500-1.1	I768N	Pathogenic	0.932
NPHS1	O60500-1.1	I768P	Pathogenic	0.69
NPHS1	O60500-1.1	I768Q	Pathogenic	0.836
NPHS1	O60500-1.1	I768R	Pathogenic	0.958
NPHS1	O60500-1.1	I768S	Pathogenic	0.939
NPHS1	O60500-1.1	I768T	Pathogenic	0.902
NPHS1	O60500-1.1	I768V	Pathogenic	0.891
NPHS1	O60500-1.1	I768W	Neutral	0.493
NPHS1	O60500-1.1	I768Y	Pathogenic	0.698
NPHS1	O60500-1.1	L769A	Neutral	0.383
NPHS1	O60500-1.1	L769C	Neutral	0.127
NPHS1	O60500-1.1	L769D	Neutral	0.346
NPHS1	O60500-1.1	L769E	Neutral	0.297
NPHS1	O60500-1.1	L769F	Neutral	0.043
NPHS1	O60500-1.1	L769G	Neutral	0.317
NPHS1	O60500-1.1	L769H	Neutral	0.098
NPHS1	O60500-1.1	L769I	Neutral	0.073
NPHS1	O60500-1.1	L769K	Neutral	0.492
NPHS1	O60500-1.1	L769M	Neutral	0.119
NPHS1	O60500-1.1	L769N	Neutral	0.353
NPHS1	O60500-1.1	L769P	Neutral	0.081
NPHS1	O60500-1.1	L769Q	Neutral	0.231
NPHS1	O60500-1.1	L769R	Pathogenic	0.574
NPHS1	O60500-1.1	L769S	Neutral	0.377
NPHS1	O60500-1.1	L769T	Neutral	0.266
NPHS1	O60500-1.1	L769V	Neutral	0.127
NPHS1	O60500-1.1	L769W	Neutral	0.072
NPHS1	O60500-1.1	L769Y	Neutral	0.084
NPHS1	O60500-1.1	P770A	Neutral	0.44
NPHS1	O60500-1.1	P770C	Neutral	0.154
NPHS1	O60500-1.1	P770D	Pathogenic	0.699
NPHS1	O60500-1.1	P770E	Pathogenic	0.745
NPHS1	O60500-1.1	P770F	Pathogenic	0.516
NPHS1	O60500-1.1	P770G	Pathogenic	0.567
NPHS1	O60500-1.1	P770H	Neutral	0.436
NPHS1	O60500-1.1	P770I	Pathogenic	0.556
NPHS1	O60500-1.1	P770K	Pathogenic	0.901
NPHS1	O60500-1.1	P770L	Pathogenic	0.518
NPHS1	O60500-1.1	P770M	Neutral	0.444
NPHS1	O60500-1.1	P770N	Pathogenic	0.577
NPHS1	O60500-1.1	P770Q	Pathogenic	0.639
NPHS1	O60500-1.1	P770R	Pathogenic	0.895
NPHS1	O60500-1.1	P770S	Pathogenic	0.533
NPHS1	O60500-1.1	P770T	Neutral	0.346
NPHS1	O60500-1.1	P770V	Neutral	0.332
NPHS1	O60500-1.1	P770W	Pathogenic	0.804
NPHS1	O60500-1.1	P770Y	Neutral	0.348
NPHS1	O60500-1.1	G771A	Neutral	0.03
NPHS1	O60500-1.1	G771C	Neutral	0.038
NPHS1	O60500-1.1	G771D	Neutral	0.067
NPHS1	O60500-1.1	G771E	Neutral	0.057
NPHS1	O60500-1.1	G771F	Neutral	0.294
NPHS1	O60500-1.1	G771H	Neutral	0.034
NPHS1	O60500-1.1	G771I	Neutral	0.18
NPHS1	O60500-1.1	G771K	Neutral	0.159
NPHS1	O60500-1.1	G771L	Neutral	0.159
NPHS1	O60500-1.1	G771M	Neutral	0.123
NPHS1	O60500-1.1	G771N	Neutral	0.086
NPHS1	O60500-1.1	G771P	Neutral	0.042
NPHS1	O60500-1.1	G771Q	Neutral	0.035
NPHS1	O60500-1.1	G771R	Neutral	0.208
NPHS1	O60500-1.1	G771S	Neutral	0.023
NPHS1	O60500-1.1	G771T	Neutral	0.023
NPHS1	O60500-1.1	G771V	Neutral	0.081
NPHS1	O60500-1.1	G771W	Pathogenic	0.705
NPHS1	O60500-1.1	G771Y	Neutral	0.123
NPHS1	O60500-1.1	M772A	Pathogenic	0.999
NPHS1	O60500-1.1	M772C	Pathogenic	0.998
NPHS1	O60500-1.1	M772D	Pathogenic	1.0
NPHS1	O60500-1.1	M772E	Pathogenic	1.0
NPHS1	O60500-1.1	M772F	Pathogenic	0.998
NPHS1	O60500-1.1	M772G	Pathogenic	1.0
NPHS1	O60500-1.1	M772H	Pathogenic	0.998
NPHS1	O60500-1.1	M772I	Pathogenic	0.999
NPHS1	O60500-1.1	M772K	Pathogenic	1.0
NPHS1	O60500-1.1	M772L	Pathogenic	0.999
NPHS1	O60500-1.1	M772N	Pathogenic	1.0
NPHS1	O60500-1.1	M772P	Pathogenic	0.998
NPHS1	O60500-1.1	M772Q	Pathogenic	1.0
NPHS1	O60500-1.1	M772R	Pathogenic	1.0
NPHS1	O60500-1.1	M772S	Pathogenic	1.0
NPHS1	O60500-1.1	M772T	Pathogenic	0.999
NPHS1	O60500-1.1	M772V	Pathogenic	0.998
NPHS1	O60500-1.1	M772W	Pathogenic	0.999
NPHS1	O60500-1.1	M772Y	Pathogenic	0.997
NPHS1	O60500-1.1	F773A	Pathogenic	0.999
NPHS1	O60500-1.1	F773C	Pathogenic	0.997
NPHS1	O60500-1.1	F773D	Pathogenic	1.0
NPHS1	O60500-1.1	F773E	Pathogenic	0.999
NPHS1	O60500-1.1	F773G	Pathogenic	1.0
NPHS1	O60500-1.1	F773H	Pathogenic	0.999
NPHS1	O60500-1.1	F773I	Pathogenic	0.988
NPHS1	O60500-1.1	F773K	Pathogenic	0.999
NPHS1	O60500-1.1	F773L	Pathogenic	0.99
NPHS1	O60500-1.1	F773M	Pathogenic	0.995
NPHS1	O60500-1.1	F773N	Pathogenic	0.999
NPHS1	O60500-1.1	F773P	Pathogenic	0.995
NPHS1	O60500-1.1	F773Q	Pathogenic	0.998
NPHS1	O60500-1.1	F773R	Pathogenic	0.999
NPHS1	O60500-1.1	F773S	Pathogenic	0.999
NPHS1	O60500-1.1	F773T	Pathogenic	0.999
NPHS1	O60500-1.1	F773V	Pathogenic	0.995
NPHS1	O60500-1.1	F773W	Pathogenic	0.997
NPHS1	O60500-1.1	F773Y	Pathogenic	0.999
NPHS1	O60500-1.1	N774A	Neutral	0.18
NPHS1	O60500-1.1	N774C	Neutral	0.204
NPHS1	O60500-1.1	N774D	Neutral	0.12
NPHS1	O60500-1.1	N774E	Neutral	0.084
NPHS1	O60500-1.1	N774F	Pathogenic	0.628
NPHS1	O60500-1.1	N774G	Neutral	0.326
NPHS1	O60500-1.1	N774H	Neutral	0.322
NPHS1	O60500-1.1	N774I	Pathogenic	0.571
NPHS1	O60500-1.1	N774K	Neutral	0.221
NPHS1	O60500-1.1	N774L	Pathogenic	0.533
NPHS1	O60500-1.1	N774M	Neutral	0.458
NPHS1	O60500-1.1	N774P	Neutral	0.19
NPHS1	O60500-1.1	N774Q	Neutral	0.146
NPHS1	O60500-1.1	N774R	Neutral	0.283
NPHS1	O60500-1.1	N774S	Neutral	0.274
NPHS1	O60500-1.1	N774T	Neutral	0.196
NPHS1	O60500-1.1	N774V	Neutral	0.262
NPHS1	O60500-1.1	N774W	Pathogenic	0.813
NPHS1	O60500-1.1	N774Y	Neutral	0.458
NPHS1	O60500-1.1	W775A	Pathogenic	1.0
NPHS1	O60500-1.1	W775C	Pathogenic	1.0
NPHS1	O60500-1.1	W775D	Pathogenic	1.0
NPHS1	O60500-1.1	W775E	Pathogenic	1.0
NPHS1	O60500-1.1	W775F	Pathogenic	0.999
NPHS1	O60500-1.1	W775G	Pathogenic	1.0
NPHS1	O60500-1.1	W775H	Pathogenic	1.0
NPHS1	O60500-1.1	W775I	Pathogenic	0.997
NPHS1	O60500-1.1	W775K	Pathogenic	1.0
NPHS1	O60500-1.1	W775L	Pathogenic	0.998
NPHS1	O60500-1.1	W775M	Pathogenic	0.999
NPHS1	O60500-1.1	W775N	Pathogenic	1.0
NPHS1	O60500-1.1	W775P	Pathogenic	1.0
NPHS1	O60500-1.1	W775Q	Pathogenic	1.0
NPHS1	O60500-1.1	W775R	Pathogenic	1.0
NPHS1	O60500-1.1	W775S	Pathogenic	1.0
NPHS1	O60500-1.1	W775T	Pathogenic	1.0
NPHS1	O60500-1.1	W775V	Pathogenic	0.999
NPHS1	O60500-1.1	W775Y	Pathogenic	1.0
NPHS1	O60500-1.1	E776A	Neutral	0.48
NPHS1	O60500-1.1	E776C	Neutral	0.327
NPHS1	O60500-1.1	E776D	Neutral	0.341
NPHS1	O60500-1.1	E776F	Pathogenic	0.721
NPHS1	O60500-1.1	E776G	Neutral	0.381
NPHS1	O60500-1.1	E776H	Neutral	0.327
NPHS1	O60500-1.1	E776I	Pathogenic	0.67
NPHS1	O60500-1.1	E776K	Neutral	0.368
NPHS1	O60500-1.1	E776L	Pathogenic	0.636
NPHS1	O60500-1.1	E776M	Pathogenic	0.564
NPHS1	O60500-1.1	E776N	Neutral	0.152
NPHS1	O60500-1.1	E776P	Neutral	0.497
NPHS1	O60500-1.1	E776Q	Neutral	0.368
NPHS1	O60500-1.1	E776R	Neutral	0.352
NPHS1	O60500-1.1	E776S	Neutral	0.417
NPHS1	O60500-1.1	E776T	Neutral	0.317
NPHS1	O60500-1.1	E776V	Neutral	0.494
NPHS1	O60500-1.1	E776W	Pathogenic	0.909
NPHS1	O60500-1.1	E776Y	Pathogenic	0.564
NPHS1	O60500-1.1	R777A	Pathogenic	0.902
NPHS1	O60500-1.1	R777C	Pathogenic	0.878
NPHS1	O60500-1.1	R777D	Neutral	0.413
NPHS1	O60500-1.1	R777E	Pathogenic	0.555
NPHS1	O60500-1.1	R777F	Pathogenic	0.883
NPHS1	O60500-1.1	R777G	Pathogenic	0.859
NPHS1	O60500-1.1	R777H	Pathogenic	0.76
NPHS1	O60500-1.1	R777I	Pathogenic	0.909
NPHS1	O60500-1.1	R777K	Neutral	0.47
NPHS1	O60500-1.1	R777L	Pathogenic	0.927
NPHS1	O60500-1.1	R777M	Pathogenic	0.904
NPHS1	O60500-1.1	R777N	Pathogenic	0.641
NPHS1	O60500-1.1	R777P	Pathogenic	0.868
NPHS1	O60500-1.1	R777Q	Pathogenic	0.754
NPHS1	O60500-1.1	R777S	Pathogenic	0.827
NPHS1	O60500-1.1	R777T	Pathogenic	0.822
NPHS1	O60500-1.1	R777V	Pathogenic	0.867
NPHS1	O60500-1.1	R777W	Pathogenic	0.94
NPHS1	O60500-1.1	R777Y	Pathogenic	0.739
NPHS1	O60500-1.1	L778A	Pathogenic	0.983
NPHS1	O60500-1.1	L778C	Pathogenic	0.93
NPHS1	O60500-1.1	L778D	Pathogenic	0.98
NPHS1	O60500-1.1	L778E	Pathogenic	0.975
NPHS1	O60500-1.1	L778F	Pathogenic	0.805
NPHS1	O60500-1.1	L778G	Pathogenic	0.977
NPHS1	O60500-1.1	L778H	Pathogenic	0.909
NPHS1	O60500-1.1	L778I	Pathogenic	0.878
NPHS1	O60500-1.1	L778K	Pathogenic	0.989
NPHS1	O60500-1.1	L778M	Pathogenic	0.926
NPHS1	O60500-1.1	L778N	Pathogenic	0.98
NPHS1	O60500-1.1	L778P	Pathogenic	0.89
NPHS1	O60500-1.1	L778Q	Pathogenic	0.965
NPHS1	O60500-1.1	L778R	Pathogenic	0.992
NPHS1	O60500-1.1	L778S	Pathogenic	0.982
NPHS1	O60500-1.1	L778T	Pathogenic	0.971
NPHS1	O60500-1.1	L778V	Pathogenic	0.93
NPHS1	O60500-1.1	L778W	Pathogenic	0.877
NPHS1	O60500-1.1	L778Y	Pathogenic	0.894
NPHS1	O60500-1.1	G779A	Pathogenic	0.906
NPHS1	O60500-1.1	G779C	Pathogenic	0.925
NPHS1	O60500-1.1	G779D	Pathogenic	0.958
NPHS1	O60500-1.1	G779E	Pathogenic	0.95
NPHS1	O60500-1.1	G779F	Pathogenic	0.992
NPHS1	O60500-1.1	G779H	Pathogenic	0.917
NPHS1	O60500-1.1	G779I	Pathogenic	0.986
NPHS1	O60500-1.1	G779K	Pathogenic	0.983
NPHS1	O60500-1.1	G779L	Pathogenic	0.983
NPHS1	O60500-1.1	G779M	Pathogenic	0.978
NPHS1	O60500-1.1	G779N	Pathogenic	0.967
NPHS1	O60500-1.1	G779P	Pathogenic	0.932
NPHS1	O60500-1.1	G779Q	Pathogenic	0.92
NPHS1	O60500-1.1	G779R	Pathogenic	0.988
NPHS1	O60500-1.1	G779S	Pathogenic	0.881
NPHS1	O60500-1.1	G779T	Pathogenic	0.881
NPHS1	O60500-1.1	G779V	Pathogenic	0.965
NPHS1	O60500-1.1	G779W	Pathogenic	0.999
NPHS1	O60500-1.1	G779Y	Pathogenic	0.978
NPHS1	O60500-1.1	E780A	Pathogenic	0.883
NPHS1	O60500-1.1	E780C	Pathogenic	0.799
NPHS1	O60500-1.1	E780D	Pathogenic	0.809
NPHS1	O60500-1.1	E780F	Pathogenic	0.955
NPHS1	O60500-1.1	E780G	Pathogenic	0.834
NPHS1	O60500-1.1	E780H	Pathogenic	0.799
NPHS1	O60500-1.1	E780I	Pathogenic	0.943
NPHS1	O60500-1.1	E780K	Pathogenic	0.826
NPHS1	O60500-1.1	E780L	Pathogenic	0.934
NPHS1	O60500-1.1	E780M	Pathogenic	0.914
NPHS1	O60500-1.1	E780N	Pathogenic	0.595
NPHS1	O60500-1.1	E780P	Pathogenic	0.89
NPHS1	O60500-1.1	E780Q	Pathogenic	0.827
NPHS1	O60500-1.1	E780R	Pathogenic	0.816
NPHS1	O60500-1.1	E780S	Pathogenic	0.854
NPHS1	O60500-1.1	E780T	Pathogenic	0.791
NPHS1	O60500-1.1	E780V	Pathogenic	0.889
NPHS1	O60500-1.1	E780W	Pathogenic	0.988
NPHS1	O60500-1.1	E780Y	Pathogenic	0.914
NPHS1	O60500-1.1	D781A	Neutral	0.127
NPHS1	O60500-1.1	D781C	Neutral	0.145
NPHS1	O60500-1.1	D781E	Neutral	0.132
NPHS1	O60500-1.1	D781F	Pathogenic	0.586
NPHS1	O60500-1.1	D781G	Neutral	0.177
NPHS1	O60500-1.1	D781H	Neutral	0.152
NPHS1	O60500-1.1	D781I	Pathogenic	0.527
NPHS1	O60500-1.1	D781K	Neutral	0.088
NPHS1	O60500-1.1	D781L	Neutral	0.391
NPHS1	O60500-1.1	D781M	Neutral	0.322
NPHS1	O60500-1.1	D781N	Neutral	0.074
NPHS1	O60500-1.1	D781P	Neutral	0.188
NPHS1	O60500-1.1	D781Q	Neutral	0.126
NPHS1	O60500-1.1	D781R	Neutral	0.083
NPHS1	O60500-1.1	D781S	Neutral	0.144
NPHS1	O60500-1.1	D781T	Neutral	0.106
NPHS1	O60500-1.1	D781V	Neutral	0.229
NPHS1	O60500-1.1	D781W	Pathogenic	0.785
NPHS1	O60500-1.1	D781Y	Neutral	0.322
NPHS1	O60500-1.1	E782A	Pathogenic	0.633
NPHS1	O60500-1.1	E782C	Neutral	0.475
NPHS1	O60500-1.1	E782D	Neutral	0.491
NPHS1	O60500-1.1	E782F	Pathogenic	0.828
NPHS1	O60500-1.1	E782G	Pathogenic	0.534
NPHS1	O60500-1.1	E782H	Neutral	0.475
NPHS1	O60500-1.1	E782I	Pathogenic	0.791
NPHS1	O60500-1.1	E782K	Pathogenic	0.52
NPHS1	O60500-1.1	E782L	Pathogenic	0.765
NPHS1	O60500-1.1	E782M	Pathogenic	0.707
NPHS1	O60500-1.1	E782N	Neutral	0.251
NPHS1	O60500-1.1	E782P	Pathogenic	0.648
NPHS1	O60500-1.1	E782Q	Pathogenic	0.521
NPHS1	O60500-1.1	E782R	Pathogenic	0.503
NPHS1	O60500-1.1	E782S	Pathogenic	0.572
NPHS1	O60500-1.1	E782T	Neutral	0.463
NPHS1	O60500-1.1	E782V	Pathogenic	0.645
NPHS1	O60500-1.1	E782W	Pathogenic	0.949
NPHS1	O60500-1.1	E782Y	Pathogenic	0.706
NPHS1	O60500-1.1	E783A	Pathogenic	0.562
NPHS1	O60500-1.1	E783C	Neutral	0.403
NPHS1	O60500-1.1	E783D	Neutral	0.418
NPHS1	O60500-1.1	E783F	Pathogenic	0.782
NPHS1	O60500-1.1	E783G	Neutral	0.46
NPHS1	O60500-1.1	E783H	Neutral	0.403
NPHS1	O60500-1.1	E783I	Pathogenic	0.738
NPHS1	O60500-1.1	E783K	Neutral	0.447
NPHS1	O60500-1.1	E783L	Pathogenic	0.708
NPHS1	O60500-1.1	E783M	Pathogenic	0.643
NPHS1	O60500-1.1	E783N	Neutral	0.2
NPHS1	O60500-1.1	E783P	Pathogenic	0.579
NPHS1	O60500-1.1	E783Q	Neutral	0.447
NPHS1	O60500-1.1	E783R	Neutral	0.43
NPHS1	O60500-1.1	E783S	Neutral	0.499
NPHS1	O60500-1.1	E783T	Neutral	0.391
NPHS1	O60500-1.1	E783V	Pathogenic	0.576
NPHS1	O60500-1.1	E783W	Pathogenic	0.932
NPHS1	O60500-1.1	E783Y	Pathogenic	0.642
NPHS1	O60500-1.1	D784A	Pathogenic	0.655
NPHS1	O60500-1.1	D784C	Pathogenic	0.689
NPHS1	O60500-1.1	D784E	Pathogenic	0.666
NPHS1	O60500-1.1	D784F	Pathogenic	0.949
NPHS1	O60500-1.1	D784G	Pathogenic	0.737
NPHS1	O60500-1.1	D784H	Pathogenic	0.7
NPHS1	O60500-1.1	D784I	Pathogenic	0.936
NPHS1	O60500-1.1	D784K	Pathogenic	0.559
NPHS1	O60500-1.1	D784L	Pathogenic	0.893
NPHS1	O60500-1.1	D784M	Pathogenic	0.861
NPHS1	O60500-1.1	D784N	Pathogenic	0.509
NPHS1	O60500-1.1	D784P	Pathogenic	0.751
NPHS1	O60500-1.1	D784Q	Pathogenic	0.652
NPHS1	O60500-1.1	D784R	Pathogenic	0.541
NPHS1	O60500-1.1	D784S	Pathogenic	0.687
NPHS1	O60500-1.1	D784T	Pathogenic	0.609
NPHS1	O60500-1.1	D784V	Pathogenic	0.795
NPHS1	O60500-1.1	D784W	Pathogenic	0.979
NPHS1	O60500-1.1	D784Y	Pathogenic	0.861
NPHS1	O60500-1.1	Q785A	Neutral	0.078
NPHS1	O60500-1.1	Q785C	Neutral	0.062
NPHS1	O60500-1.1	Q785D	Neutral	0.069
NPHS1	O60500-1.1	Q785E	Neutral	0.081
NPHS1	O60500-1.1	Q785F	Neutral	0.157
NPHS1	O60500-1.1	Q785G	Neutral	0.053
NPHS1	O60500-1.1	Q785H	Neutral	0.034
NPHS1	O60500-1.1	Q785I	Neutral	0.128
NPHS1	O60500-1.1	Q785K	Neutral	0.127
NPHS1	O60500-1.1	Q785L	Neutral	0.158
NPHS1	O60500-1.1	Q785M	Neutral	0.172
NPHS1	O60500-1.1	Q785N	Neutral	0.049
NPHS1	O60500-1.1	Q785P	Neutral	0.083
NPHS1	O60500-1.1	Q785R	Neutral	0.168
NPHS1	O60500-1.1	Q785S	Neutral	0.061
NPHS1	O60500-1.1	Q785T	Neutral	0.041
NPHS1	O60500-1.1	Q785V	Neutral	0.082
NPHS1	O60500-1.1	Q785W	Pathogenic	0.517
NPHS1	O60500-1.1	Q785Y	Neutral	0.122
NPHS1	O60500-1.1	S786A	Neutral	0.13
NPHS1	O60500-1.1	S786C	Neutral	0.178
NPHS1	O60500-1.1	S786D	Neutral	0.192
NPHS1	O60500-1.1	S786E	Neutral	0.23
NPHS1	O60500-1.1	S786F	Pathogenic	0.606
NPHS1	O60500-1.1	S786G	Neutral	0.09
NPHS1	O60500-1.1	S786H	Neutral	0.115
NPHS1	O60500-1.1	S786I	Pathogenic	0.548
NPHS1	O60500-1.1	S786K	Neutral	0.483
NPHS1	O60500-1.1	S786L	Pathogenic	0.51
NPHS1	O60500-1.1	S786M	Neutral	0.435
NPHS1	O60500-1.1	S786N	Neutral	0.237
NPHS1	O60500-1.1	S786P	Neutral	0.139
NPHS1	O60500-1.1	S786Q	Neutral	0.153
NPHS1	O60500-1.1	S786R	Neutral	0.465
NPHS1	O60500-1.1	S786T	Neutral	0.162
NPHS1	O60500-1.1	S786V	Neutral	0.244
NPHS1	O60500-1.1	S786W	Pathogenic	0.799
NPHS1	O60500-1.1	S786Y	Neutral	0.34
NPHS1	O60500-1.1	L787A	Pathogenic	0.668
NPHS1	O60500-1.1	L787C	Neutral	0.32
NPHS1	O60500-1.1	L787D	Pathogenic	0.631
NPHS1	O60500-1.1	L787E	Pathogenic	0.578
NPHS1	O60500-1.1	L787F	Neutral	0.127
NPHS1	O60500-1.1	L787G	Pathogenic	0.6
NPHS1	O60500-1.1	L787H	Neutral	0.26
NPHS1	O60500-1.1	L787I	Neutral	0.203
NPHS1	O60500-1.1	L787K	Pathogenic	0.758
NPHS1	O60500-1.1	L787M	Neutral	0.305
NPHS1	O60500-1.1	L787N	Pathogenic	0.638
NPHS1	O60500-1.1	L787P	Neutral	0.222
NPHS1	O60500-1.1	L787Q	Neutral	0.493
NPHS1	O60500-1.1	L787R	Pathogenic	0.813
NPHS1	O60500-1.1	L787S	Pathogenic	0.661
NPHS1	O60500-1.1	L787T	Pathogenic	0.54
NPHS1	O60500-1.1	L787V	Neutral	0.32
NPHS1	O60500-1.1	L787W	Neutral	0.201
NPHS1	O60500-1.1	L787Y	Neutral	0.228
NPHS1	O60500-1.1	D788A	Neutral	0.358
NPHS1	O60500-1.1	D788C	Neutral	0.395
NPHS1	O60500-1.1	D788E	Neutral	0.37
NPHS1	O60500-1.1	D788F	Pathogenic	0.845
NPHS1	O60500-1.1	D788G	Neutral	0.452
NPHS1	O60500-1.1	D788H	Neutral	0.407
NPHS1	O60500-1.1	D788I	Pathogenic	0.811
NPHS1	O60500-1.1	D788K	Neutral	0.271
NPHS1	O60500-1.1	D788L	Pathogenic	0.712
NPHS1	O60500-1.1	D788M	Pathogenic	0.647
NPHS1	O60500-1.1	D788N	Neutral	0.234
NPHS1	O60500-1.1	D788P	Neutral	0.471
NPHS1	O60500-1.1	D788Q	Neutral	0.356
NPHS1	O60500-1.1	D788R	Neutral	0.258
NPHS1	O60500-1.1	D788S	Neutral	0.392
NPHS1	O60500-1.1	D788T	Neutral	0.314
NPHS1	O60500-1.1	D788V	Pathogenic	0.533
NPHS1	O60500-1.1	D788W	Pathogenic	0.934
NPHS1	O60500-1.1	D788Y	Pathogenic	0.646
NPHS1	O60500-1.1	D789A	Pathogenic	0.501
NPHS1	O60500-1.1	D789C	Pathogenic	0.54
NPHS1	O60500-1.1	D789E	Pathogenic	0.514
NPHS1	O60500-1.1	D789F	Pathogenic	0.907
NPHS1	O60500-1.1	D789G	Pathogenic	0.598
NPHS1	O60500-1.1	D789H	Pathogenic	0.553
NPHS1	O60500-1.1	D789I	Pathogenic	0.885
NPHS1	O60500-1.1	D789K	Neutral	0.402
NPHS1	O60500-1.1	D789L	Pathogenic	0.816
NPHS1	O60500-1.1	D789M	Pathogenic	0.767
NPHS1	O60500-1.1	D789N	Neutral	0.355
NPHS1	O60500-1.1	D789P	Pathogenic	0.616
NPHS1	O60500-1.1	D789Q	Neutral	0.499
NPHS1	O60500-1.1	D789R	Neutral	0.385
NPHS1	O60500-1.1	D789S	Pathogenic	0.538
NPHS1	O60500-1.1	D789T	Neutral	0.452
NPHS1	O60500-1.1	D789V	Pathogenic	0.673
NPHS1	O60500-1.1	D789W	Pathogenic	0.962
NPHS1	O60500-1.1	D789Y	Pathogenic	0.767
NPHS1	O60500-1.1	M790A	Pathogenic	0.933
NPHS1	O60500-1.1	M790C	Pathogenic	0.764
NPHS1	O60500-1.1	M790D	Pathogenic	0.946
NPHS1	O60500-1.1	M790E	Pathogenic	0.934
NPHS1	O60500-1.1	M790F	Pathogenic	0.802
NPHS1	O60500-1.1	M790G	Pathogenic	0.939
NPHS1	O60500-1.1	M790H	Pathogenic	0.783
NPHS1	O60500-1.1	M790I	Pathogenic	0.826
NPHS1	O60500-1.1	M790K	Pathogenic	0.97
NPHS1	O60500-1.1	M790L	Pathogenic	0.859
NPHS1	O60500-1.1	M790N	Pathogenic	0.948
NPHS1	O60500-1.1	M790P	Pathogenic	0.745
NPHS1	O60500-1.1	M790Q	Pathogenic	0.937
NPHS1	O60500-1.1	M790R	Pathogenic	0.978
NPHS1	O60500-1.1	M790S	Pathogenic	0.953
NPHS1	O60500-1.1	M790T	Pathogenic	0.89
NPHS1	O60500-1.1	M790V	Pathogenic	0.764
NPHS1	O60500-1.1	M790W	Pathogenic	0.913
NPHS1	O60500-1.1	M790Y	Pathogenic	0.671
NPHS1	O60500-1.1	E791A	Pathogenic	0.948
NPHS1	O60500-1.1	E791C	Pathogenic	0.905
NPHS1	O60500-1.1	E791D	Pathogenic	0.911
NPHS1	O60500-1.1	E791F	Pathogenic	0.981
NPHS1	O60500-1.1	E791G	Pathogenic	0.924
NPHS1	O60500-1.1	E791H	Pathogenic	0.906
NPHS1	O60500-1.1	E791I	Pathogenic	0.976
NPHS1	O60500-1.1	E791K	Pathogenic	0.92
NPHS1	O60500-1.1	E791L	Pathogenic	0.972
NPHS1	O60500-1.1	E791M	Pathogenic	0.962
NPHS1	O60500-1.1	E791N	Pathogenic	0.78
NPHS1	O60500-1.1	E791P	Pathogenic	0.951
NPHS1	O60500-1.1	E791Q	Pathogenic	0.92
NPHS1	O60500-1.1	E791R	Pathogenic	0.915
NPHS1	O60500-1.1	E791S	Pathogenic	0.934
NPHS1	O60500-1.1	E791T	Pathogenic	0.901
NPHS1	O60500-1.1	E791V	Pathogenic	0.951
NPHS1	O60500-1.1	E791W	Pathogenic	0.995
NPHS1	O60500-1.1	E791Y	Pathogenic	0.962
NPHS1	O60500-1.1	K792A	Pathogenic	0.581
NPHS1	O60500-1.1	K792C	Pathogenic	0.52
NPHS1	O60500-1.1	K792D	Neutral	0.136
NPHS1	O60500-1.1	K792E	Neutral	0.218
NPHS1	O60500-1.1	K792F	Pathogenic	0.531
NPHS1	O60500-1.1	K792G	Neutral	0.479
NPHS1	O60500-1.1	K792H	Neutral	0.242
NPHS1	O60500-1.1	K792I	Pathogenic	0.6
NPHS1	O60500-1.1	K792L	Pathogenic	0.657
NPHS1	O60500-1.1	K792M	Pathogenic	0.587
NPHS1	O60500-1.1	K792N	Neutral	0.212
NPHS1	O60500-1.1	K792P	Pathogenic	0.597
NPHS1	O60500-1.1	K792Q	Neutral	0.316
NPHS1	O60500-1.1	K792R	Neutral	0.156
NPHS1	O60500-1.1	K792S	Pathogenic	0.518
NPHS1	O60500-1.1	K792T	Neutral	0.41
NPHS1	O60500-1.1	K792V	Pathogenic	0.594
NPHS1	O60500-1.1	K792W	Pathogenic	0.813
NPHS1	O60500-1.1	K792Y	Neutral	0.362
NPHS1	O60500-1.1	I793A	Neutral	0.1
NPHS1	O60500-1.1	I793C	Neutral	0.025
NPHS1	O60500-1.1	I793D	Neutral	0.124
NPHS1	O60500-1.1	I793E	Neutral	0.071
NPHS1	O60500-1.1	I793F	Neutral	0.006
NPHS1	O60500-1.1	I793G	Neutral	0.077
NPHS1	O60500-1.1	I793H	Neutral	0.019
NPHS1	O60500-1.1	I793K	Neutral	0.105
NPHS1	O60500-1.1	I793L	Neutral	0.012
NPHS1	O60500-1.1	I793M	Neutral	0.016
NPHS1	O60500-1.1	I793N	Neutral	0.089
NPHS1	O60500-1.1	I793P	Neutral	0.016
NPHS1	O60500-1.1	I793Q	Neutral	0.035
NPHS1	O60500-1.1	I793R	Neutral	0.14
NPHS1	O60500-1.1	I793S	Neutral	0.098
NPHS1	O60500-1.1	I793T	Neutral	0.061
NPHS1	O60500-1.1	I793V	Neutral	0.055
NPHS1	O60500-1.1	I793W	Neutral	0.007
NPHS1	O60500-1.1	I793Y	Neutral	0.016
NPHS1	O60500-1.1	S794A	Neutral	0.218
NPHS1	O60500-1.1	S794C	Neutral	0.288
NPHS1	O60500-1.1	S794D	Neutral	0.307
NPHS1	O60500-1.1	S794E	Neutral	0.358
NPHS1	O60500-1.1	S794F	Pathogenic	0.741
NPHS1	O60500-1.1	S794G	Neutral	0.156
NPHS1	O60500-1.1	S794H	Neutral	0.195
NPHS1	O60500-1.1	S794I	Pathogenic	0.693
NPHS1	O60500-1.1	S794K	Pathogenic	0.635
NPHS1	O60500-1.1	S794L	Pathogenic	0.659
NPHS1	O60500-1.1	S794M	Pathogenic	0.59
NPHS1	O60500-1.1	S794N	Neutral	0.366
NPHS1	O60500-1.1	S794P	Neutral	0.231
NPHS1	O60500-1.1	S794Q	Neutral	0.252
NPHS1	O60500-1.1	S794R	Pathogenic	0.618
NPHS1	O60500-1.1	S794T	Neutral	0.265
NPHS1	O60500-1.1	S794V	Neutral	0.376
NPHS1	O60500-1.1	S794W	Pathogenic	0.881
NPHS1	O60500-1.1	S794Y	Neutral	0.49
NPHS1	O60500-1.1	R795A	Neutral	0.018
NPHS1	O60500-1.1	R795C	Neutral	0.014
NPHS1	O60500-1.1	R795D	Neutral	0.001
NPHS1	O60500-1.1	R795E	Neutral	0.002
NPHS1	O60500-1.1	R795F	Neutral	0.015
NPHS1	O60500-1.1	R795G	Neutral	0.012
NPHS1	O60500-1.1	R795H	Neutral	0.006
NPHS1	O60500-1.1	R795I	Neutral	0.019
NPHS1	O60500-1.1	R795K	Neutral	0.002
NPHS1	O60500-1.1	R795L	Neutral	0.024
NPHS1	O60500-1.1	R795M	Neutral	0.018
NPHS1	O60500-1.1	R795N	Neutral	0.003
NPHS1	O60500-1.1	R795P	Neutral	0.013
NPHS1	O60500-1.1	R795Q	Neutral	0.006
NPHS1	O60500-1.1	R795S	Neutral	0.009
NPHS1	O60500-1.1	R795T	Neutral	0.009
NPHS1	O60500-1.1	R795V	Neutral	0.013
NPHS1	O60500-1.1	R795W	Neutral	0.03
NPHS1	O60500-1.1	R795Y	Neutral	0.006
NPHS1	O60500-1.1	G796A	Pathogenic	0.73
NPHS1	O60500-1.1	G796C	Pathogenic	0.777
NPHS1	O60500-1.1	G796D	Pathogenic	0.864
NPHS1	O60500-1.1	G796E	Pathogenic	0.843
NPHS1	O60500-1.1	G796F	Pathogenic	0.974
NPHS1	O60500-1.1	G796H	Pathogenic	0.758
NPHS1	O60500-1.1	G796I	Pathogenic	0.951
NPHS1	O60500-1.1	G796K	Pathogenic	0.944
NPHS1	O60500-1.1	G796L	Pathogenic	0.944
NPHS1	O60500-1.1	G796M	Pathogenic	0.925
NPHS1	O60500-1.1	G796N	Pathogenic	0.893
NPHS1	O60500-1.1	G796P	Pathogenic	0.794
NPHS1	O60500-1.1	G796Q	Pathogenic	0.764
NPHS1	O60500-1.1	G796R	Pathogenic	0.959
NPHS1	O60500-1.1	G796S	Pathogenic	0.676
NPHS1	O60500-1.1	G796T	Pathogenic	0.676
NPHS1	O60500-1.1	G796V	Pathogenic	0.886
NPHS1	O60500-1.1	G796W	Pathogenic	0.995
NPHS1	O60500-1.1	G796Y	Pathogenic	0.925
NPHS1	O60500-1.1	P797A	Neutral	0.003
NPHS1	O60500-1.1	P797C	Neutral	0.001
NPHS1	O60500-1.1	P797D	Neutral	0.008
NPHS1	O60500-1.1	P797E	Neutral	0.01
NPHS1	O60500-1.1	P797F	Neutral	0.004
NPHS1	O60500-1.1	P797G	Neutral	0.005
NPHS1	O60500-1.1	P797H	Neutral	0.003
NPHS1	O60500-1.1	P797I	Neutral	0.004
NPHS1	O60500-1.1	P797K	Neutral	0.031
NPHS1	O60500-1.1	P797L	Neutral	0.004
NPHS1	O60500-1.1	P797M	Neutral	0.003
NPHS1	O60500-1.1	P797N	Neutral	0.005
NPHS1	O60500-1.1	P797Q	Neutral	0.006
NPHS1	O60500-1.1	P797R	Neutral	0.029
NPHS1	O60500-1.1	P797S	Neutral	0.004
NPHS1	O60500-1.1	P797T	Neutral	0.002
NPHS1	O60500-1.1	P797V	Neutral	0.002
NPHS1	O60500-1.1	P797W	Neutral	0.014
NPHS1	O60500-1.1	P797Y	Neutral	0.002
NPHS1	O60500-1.1	T798A	Pathogenic	0.631
NPHS1	O60500-1.1	T798C	Pathogenic	0.666
NPHS1	O60500-1.1	T798D	Pathogenic	0.735
NPHS1	O60500-1.1	T798E	Pathogenic	0.76
NPHS1	O60500-1.1	T798F	Pathogenic	0.91
NPHS1	O60500-1.1	T798G	Pathogenic	0.62
NPHS1	O60500-1.1	T798H	Neutral	0.456
NPHS1	O60500-1.1	T798I	Pathogenic	0.923
NPHS1	O60500-1.1	T798K	Pathogenic	0.908
NPHS1	O60500-1.1	T798L	Pathogenic	0.911
NPHS1	O60500-1.1	T798M	Pathogenic	0.836
NPHS1	O60500-1.1	T798N	Pathogenic	0.767
NPHS1	O60500-1.1	T798P	Pathogenic	0.551
NPHS1	O60500-1.1	T798Q	Pathogenic	0.657
NPHS1	O60500-1.1	T798R	Pathogenic	0.932
NPHS1	O60500-1.1	T798S	Pathogenic	0.76
NPHS1	O60500-1.1	T798V	Pathogenic	0.826
NPHS1	O60500-1.1	T798W	Pathogenic	0.975
NPHS1	O60500-1.1	T798Y	Pathogenic	0.773
NPHS1	O60500-1.1	G799A	Pathogenic	0.89
NPHS1	O60500-1.1	G799C	Pathogenic	0.913
NPHS1	O60500-1.1	G799D	Pathogenic	0.95
NPHS1	O60500-1.1	G799E	Pathogenic	0.941
NPHS1	O60500-1.1	G799F	Pathogenic	0.991
NPHS1	O60500-1.1	G799H	Pathogenic	0.903
NPHS1	O60500-1.1	G799I	Pathogenic	0.983
NPHS1	O60500-1.1	G799K	Pathogenic	0.98
NPHS1	O60500-1.1	G799L	Pathogenic	0.98
NPHS1	O60500-1.1	G799M	Pathogenic	0.974
NPHS1	O60500-1.1	G799N	Pathogenic	0.961
NPHS1	O60500-1.1	G799P	Pathogenic	0.92
NPHS1	O60500-1.1	G799Q	Pathogenic	0.907
NPHS1	O60500-1.1	G799R	Pathogenic	0.986
NPHS1	O60500-1.1	G799S	Pathogenic	0.862
NPHS1	O60500-1.1	G799T	Pathogenic	0.862
NPHS1	O60500-1.1	G799V	Pathogenic	0.959
NPHS1	O60500-1.1	G799W	Pathogenic	0.998
NPHS1	O60500-1.1	G799Y	Pathogenic	0.974
NPHS1	O60500-1.1	R800A	Pathogenic	0.709
NPHS1	O60500-1.1	R800C	Pathogenic	0.656
NPHS1	O60500-1.1	R800D	Neutral	0.157
NPHS1	O60500-1.1	R800E	Neutral	0.248
NPHS1	O60500-1.1	R800F	Pathogenic	0.666
NPHS1	O60500-1.1	R800G	Pathogenic	0.618
NPHS1	O60500-1.1	R800H	Neutral	0.456
NPHS1	O60500-1.1	R800I	Pathogenic	0.725
NPHS1	O60500-1.1	R800K	Neutral	0.19
NPHS1	O60500-1.1	R800L	Pathogenic	0.772
NPHS1	O60500-1.1	R800M	Pathogenic	0.715
NPHS1	O60500-1.1	R800N	Neutral	0.321
NPHS1	O60500-1.1	R800P	Pathogenic	0.636
NPHS1	O60500-1.1	R800Q	Neutral	0.449
NPHS1	O60500-1.1	R800S	Pathogenic	0.559
NPHS1	O60500-1.1	R800T	Pathogenic	0.55
NPHS1	O60500-1.1	R800V	Pathogenic	0.633
NPHS1	O60500-1.1	R800W	Pathogenic	0.806
NPHS1	O60500-1.1	R800Y	Neutral	0.429
NPHS1	O60500-1.1	L801A	Pathogenic	0.997
NPHS1	O60500-1.1	L801C	Pathogenic	0.986
NPHS1	O60500-1.1	L801D	Pathogenic	0.996
NPHS1	O60500-1.1	L801E	Pathogenic	0.995
NPHS1	O60500-1.1	L801F	Pathogenic	0.956
NPHS1	O60500-1.1	L801G	Pathogenic	0.996
NPHS1	O60500-1.1	L801H	Pathogenic	0.981
NPHS1	O60500-1.1	L801I	Pathogenic	0.975
NPHS1	O60500-1.1	L801K	Pathogenic	0.998
NPHS1	O60500-1.1	L801M	Pathogenic	0.985
NPHS1	O60500-1.1	L801N	Pathogenic	0.996
NPHS1	O60500-1.1	L801P	Pathogenic	0.977
NPHS1	O60500-1.1	L801Q	Pathogenic	0.993
NPHS1	O60500-1.1	L801R	Pathogenic	0.998
NPHS1	O60500-1.1	L801S	Pathogenic	0.997
NPHS1	O60500-1.1	L801T	Pathogenic	0.994
NPHS1	O60500-1.1	L801V	Pathogenic	0.986
NPHS1	O60500-1.1	L801W	Pathogenic	0.974
NPHS1	O60500-1.1	L801Y	Pathogenic	0.978
NPHS1	O60500-1.1	R802A	Pathogenic	0.586
NPHS1	O60500-1.1	R802C	Pathogenic	0.526
NPHS1	O60500-1.1	R802D	Neutral	0.098
NPHS1	O60500-1.1	R802E	Neutral	0.161
NPHS1	O60500-1.1	R802F	Pathogenic	0.536
NPHS1	O60500-1.1	R802G	Neutral	0.485
NPHS1	O60500-1.1	R802H	Neutral	0.328
NPHS1	O60500-1.1	R802I	Pathogenic	0.605
NPHS1	O60500-1.1	R802K	Neutral	0.12
NPHS1	O60500-1.1	R802L	Pathogenic	0.663
NPHS1	O60500-1.1	R802M	Pathogenic	0.593
NPHS1	O60500-1.1	R802N	Neutral	0.216
NPHS1	O60500-1.1	R802P	Pathogenic	0.504
NPHS1	O60500-1.1	R802Q	Neutral	0.321
NPHS1	O60500-1.1	R802S	Neutral	0.424
NPHS1	O60500-1.1	R802T	Neutral	0.415
NPHS1	O60500-1.1	R802V	Pathogenic	0.501
NPHS1	O60500-1.1	R802W	Pathogenic	0.707
NPHS1	O60500-1.1	R802Y	Neutral	0.304
NPHS1	O60500-1.1	I803A	Pathogenic	0.998
NPHS1	O60500-1.1	I803C	Pathogenic	0.99
NPHS1	O60500-1.1	I803D	Pathogenic	0.998
NPHS1	O60500-1.1	I803E	Pathogenic	0.996
NPHS1	O60500-1.1	I803F	Pathogenic	0.958
NPHS1	O60500-1.1	I803G	Pathogenic	0.997
NPHS1	O60500-1.1	I803H	Pathogenic	0.986
NPHS1	O60500-1.1	I803K	Pathogenic	0.998
NPHS1	O60500-1.1	I803L	Pathogenic	0.978
NPHS1	O60500-1.1	I803M	Pathogenic	0.984
NPHS1	O60500-1.1	I803N	Pathogenic	0.997
NPHS1	O60500-1.1	I803P	Pathogenic	0.983
NPHS1	O60500-1.1	I803Q	Pathogenic	0.993
NPHS1	O60500-1.1	I803R	Pathogenic	0.998
NPHS1	O60500-1.1	I803S	Pathogenic	0.998
NPHS1	O60500-1.1	I803T	Pathogenic	0.996
NPHS1	O60500-1.1	I803V	Pathogenic	0.995
NPHS1	O60500-1.1	I803W	Pathogenic	0.962
NPHS1	O60500-1.1	I803Y	Pathogenic	0.984
NPHS1	O60500-1.1	H804A	Neutral	0.293
NPHS1	O60500-1.1	H804C	Neutral	0.326
NPHS1	O60500-1.1	H804D	Pathogenic	0.507
NPHS1	O60500-1.1	H804E	Neutral	0.452
NPHS1	O60500-1.1	H804F	Pathogenic	0.714
NPHS1	O60500-1.1	H804G	Neutral	0.378
NPHS1	O60500-1.1	H804I	Neutral	0.47
NPHS1	O60500-1.1	H804K	Pathogenic	0.53
NPHS1	O60500-1.1	H804L	Neutral	0.432
NPHS1	O60500-1.1	H804M	Neutral	0.361
NPHS1	O60500-1.1	H804N	Pathogenic	0.613
NPHS1	O60500-1.1	H804P	Neutral	0.307
NPHS1	O60500-1.1	H804Q	Neutral	0.282
NPHS1	O60500-1.1	H804R	Pathogenic	0.7
NPHS1	O60500-1.1	H804S	Neutral	0.346
NPHS1	O60500-1.1	H804T	Neutral	0.172
NPHS1	O60500-1.1	H804V	Neutral	0.304
NPHS1	O60500-1.1	H804W	Pathogenic	0.866
NPHS1	O60500-1.1	H804Y	Pathogenic	0.736
NPHS1	O60500-1.1	H805A	Neutral	0.04
NPHS1	O60500-1.1	H805C	Neutral	0.047
NPHS1	O60500-1.1	H805D	Neutral	0.095
NPHS1	O60500-1.1	H805E	Neutral	0.077
NPHS1	O60500-1.1	H805F	Neutral	0.203
NPHS1	O60500-1.1	H805G	Neutral	0.058
NPHS1	O60500-1.1	H805I	Neutral	0.083
NPHS1	O60500-1.1	H805K	Neutral	0.103
NPHS1	O60500-1.1	H805L	Neutral	0.072
NPHS1	O60500-1.1	H805M	Neutral	0.054
NPHS1	O60500-1.1	H805N	Neutral	0.139
NPHS1	O60500-1.1	H805P	Neutral	0.043
NPHS1	O60500-1.1	H805Q	Neutral	0.038
NPHS1	O60500-1.1	H805R	Neutral	0.192
NPHS1	O60500-1.1	H805S	Neutral	0.051
NPHS1	O60500-1.1	H805T	Neutral	0.021
NPHS1	O60500-1.1	H805V	Neutral	0.043
NPHS1	O60500-1.1	H805W	Neutral	0.396
NPHS1	O60500-1.1	H805Y	Neutral	0.221
NPHS1	O60500-1.1	A806C	Pathogenic	0.978
NPHS1	O60500-1.1	A806D	Pathogenic	0.976
NPHS1	O60500-1.1	A806E	Pathogenic	0.987
NPHS1	O60500-1.1	A806F	Pathogenic	0.995
NPHS1	O60500-1.1	A806G	Pathogenic	0.962
NPHS1	O60500-1.1	A806H	Pathogenic	0.952
NPHS1	O60500-1.1	A806I	Pathogenic	0.996
NPHS1	O60500-1.1	A806K	Pathogenic	0.996
NPHS1	O60500-1.1	A806L	Pathogenic	0.995
NPHS1	O60500-1.1	A806M	Pathogenic	0.99
NPHS1	O60500-1.1	A806N	Pathogenic	0.972
NPHS1	O60500-1.1	A806P	Pathogenic	0.956
NPHS1	O60500-1.1	A806Q	Pathogenic	0.978
NPHS1	O60500-1.1	A806R	Pathogenic	0.997
NPHS1	O60500-1.1	A806S	Pathogenic	0.967
NPHS1	O60500-1.1	A806T	Pathogenic	0.953
NPHS1	O60500-1.1	A806V	Pathogenic	0.99
NPHS1	O60500-1.1	A806W	Pathogenic	0.998
NPHS1	O60500-1.1	A806Y	Pathogenic	0.986
NPHS1	O60500-1.1	K807A	Pathogenic	0.917
NPHS1	O60500-1.1	K807C	Pathogenic	0.897
NPHS1	O60500-1.1	K807D	Pathogenic	0.558
NPHS1	O60500-1.1	K807E	Pathogenic	0.691
NPHS1	O60500-1.1	K807F	Pathogenic	0.9
NPHS1	O60500-1.1	K807G	Pathogenic	0.88
NPHS1	O60500-1.1	K807H	Pathogenic	0.719
NPHS1	O60500-1.1	K807I	Pathogenic	0.923
NPHS1	O60500-1.1	K807L	Pathogenic	0.939
NPHS1	O60500-1.1	K807M	Pathogenic	0.919
NPHS1	O60500-1.1	K807N	Pathogenic	0.683
NPHS1	O60500-1.1	K807P	Pathogenic	0.922
NPHS1	O60500-1.1	K807Q	Pathogenic	0.787
NPHS1	O60500-1.1	K807R	Pathogenic	0.597
NPHS1	O60500-1.1	K807S	Pathogenic	0.896
NPHS1	O60500-1.1	K807T	Pathogenic	0.847
NPHS1	O60500-1.1	K807V	Pathogenic	0.921
NPHS1	O60500-1.1	K807W	Pathogenic	0.972
NPHS1	O60500-1.1	K807Y	Pathogenic	0.819
NPHS1	O60500-1.1	L808A	Pathogenic	0.592
NPHS1	O60500-1.1	L808C	Neutral	0.253
NPHS1	O60500-1.1	L808D	Pathogenic	0.552
NPHS1	O60500-1.1	L808E	Neutral	0.497
NPHS1	O60500-1.1	L808F	Neutral	0.095
NPHS1	O60500-1.1	L808G	Pathogenic	0.52
NPHS1	O60500-1.1	L808H	Neutral	0.203
NPHS1	O60500-1.1	L808I	Neutral	0.155
NPHS1	O60500-1.1	L808K	Pathogenic	0.693
NPHS1	O60500-1.1	L808M	Neutral	0.24
NPHS1	O60500-1.1	L808N	Pathogenic	0.56
NPHS1	O60500-1.1	L808P	Neutral	0.171
NPHS1	O60500-1.1	L808Q	Neutral	0.413
NPHS1	O60500-1.1	L808R	Pathogenic	0.759
NPHS1	O60500-1.1	L808S	Pathogenic	0.585
NPHS1	O60500-1.1	L808T	Neutral	0.459
NPHS1	O60500-1.1	L808V	Neutral	0.254
NPHS1	O60500-1.1	L808W	Neutral	0.153
NPHS1	O60500-1.1	L808Y	Neutral	0.176
NPHS1	O60500-1.1	A809C	Neutral	0.112
NPHS1	O60500-1.1	A809D	Neutral	0.105
NPHS1	O60500-1.1	A809E	Neutral	0.18
NPHS1	O60500-1.1	A809F	Neutral	0.376
NPHS1	O60500-1.1	A809G	Neutral	0.068
NPHS1	O60500-1.1	A809H	Neutral	0.055
NPHS1	O60500-1.1	A809I	Neutral	0.414
NPHS1	O60500-1.1	A809K	Neutral	0.406
NPHS1	O60500-1.1	A809L	Neutral	0.378
NPHS1	O60500-1.1	A809M	Neutral	0.232
NPHS1	O60500-1.1	A809N	Neutral	0.093
NPHS1	O60500-1.1	A809P	Neutral	0.059
NPHS1	O60500-1.1	A809Q	Neutral	0.117
NPHS1	O60500-1.1	A809R	Neutral	0.487
NPHS1	O60500-1.1	A809S	Neutral	0.078
NPHS1	O60500-1.1	A809T	Neutral	0.056
NPHS1	O60500-1.1	A809V	Neutral	0.22
NPHS1	O60500-1.1	A809W	Pathogenic	0.609
NPHS1	O60500-1.1	A809Y	Neutral	0.168
NPHS1	O60500-1.1	Q810A	Pathogenic	0.863
NPHS1	O60500-1.1	Q810C	Pathogenic	0.831
NPHS1	O60500-1.1	Q810D	Pathogenic	0.846
NPHS1	O60500-1.1	Q810E	Pathogenic	0.868
NPHS1	O60500-1.1	Q810F	Pathogenic	0.933
NPHS1	O60500-1.1	Q810G	Pathogenic	0.807
NPHS1	O60500-1.1	Q810H	Pathogenic	0.724
NPHS1	O60500-1.1	Q810I	Pathogenic	0.916
NPHS1	O60500-1.1	Q810K	Pathogenic	0.916
NPHS1	O60500-1.1	Q810L	Pathogenic	0.933
NPHS1	O60500-1.1	Q810M	Pathogenic	0.939
NPHS1	O60500-1.1	Q810N	Pathogenic	0.792
NPHS1	O60500-1.1	Q810P	Pathogenic	0.871
NPHS1	O60500-1.1	Q810R	Pathogenic	0.938
NPHS1	O60500-1.1	Q810S	Pathogenic	0.83
NPHS1	O60500-1.1	Q810T	Pathogenic	0.759
NPHS1	O60500-1.1	Q810V	Pathogenic	0.869
NPHS1	O60500-1.1	Q810W	Pathogenic	0.988
NPHS1	O60500-1.1	Q810Y	Pathogenic	0.912
NPHS1	O60500-1.1	A811C	Pathogenic	0.944
NPHS1	O60500-1.1	A811D	Pathogenic	0.939
NPHS1	O60500-1.1	A811E	Pathogenic	0.967
NPHS1	O60500-1.1	A811F	Pathogenic	0.988
NPHS1	O60500-1.1	A811G	Pathogenic	0.907
NPHS1	O60500-1.1	A811H	Pathogenic	0.884
NPHS1	O60500-1.1	A811I	Pathogenic	0.989
NPHS1	O60500-1.1	A811K	Pathogenic	0.989
NPHS1	O60500-1.1	A811L	Pathogenic	0.988
NPHS1	O60500-1.1	A811M	Pathogenic	0.976
NPHS1	O60500-1.1	A811N	Pathogenic	0.931
NPHS1	O60500-1.1	A811P	Pathogenic	0.893
NPHS1	O60500-1.1	A811Q	Pathogenic	0.946
NPHS1	O60500-1.1	A811R	Pathogenic	0.992
NPHS1	O60500-1.1	A811S	Pathogenic	0.918
NPHS1	O60500-1.1	A811T	Pathogenic	0.886
NPHS1	O60500-1.1	A811V	Pathogenic	0.974
NPHS1	O60500-1.1	A811W	Pathogenic	0.995
NPHS1	O60500-1.1	A811Y	Pathogenic	0.964
NPHS1	O60500-1.1	G812A	Pathogenic	0.985
NPHS1	O60500-1.1	G812C	Pathogenic	0.988
NPHS1	O60500-1.1	G812D	Pathogenic	0.993
NPHS1	O60500-1.1	G812E	Pathogenic	0.992
NPHS1	O60500-1.1	G812F	Pathogenic	0.999
NPHS1	O60500-1.1	G812H	Pathogenic	0.987
NPHS1	O60500-1.1	G812I	Pathogenic	0.998
NPHS1	O60500-1.1	G812K	Pathogenic	0.997
NPHS1	O60500-1.1	G812L	Pathogenic	0.997
NPHS1	O60500-1.1	G812M	Pathogenic	0.997
NPHS1	O60500-1.1	G812N	Pathogenic	0.995
NPHS1	O60500-1.1	G812P	Pathogenic	0.989
NPHS1	O60500-1.1	G812Q	Pathogenic	0.987
NPHS1	O60500-1.1	G812R	Pathogenic	0.998
NPHS1	O60500-1.1	G812S	Pathogenic	0.98
NPHS1	O60500-1.1	G812T	Pathogenic	0.98
NPHS1	O60500-1.1	G812V	Pathogenic	0.995
NPHS1	O60500-1.1	G812W	Pathogenic	1.0
NPHS1	O60500-1.1	G812Y	Pathogenic	0.997
NPHS1	O60500-1.1	A813C	Neutral	0.211
NPHS1	O60500-1.1	A813D	Neutral	0.198
NPHS1	O60500-1.1	A813E	Neutral	0.316
NPHS1	O60500-1.1	A813F	Pathogenic	0.559
NPHS1	O60500-1.1	A813G	Neutral	0.134
NPHS1	O60500-1.1	A813H	Neutral	0.109
NPHS1	O60500-1.1	A813I	Pathogenic	0.599
NPHS1	O60500-1.1	A813K	Pathogenic	0.59
NPHS1	O60500-1.1	A813L	Pathogenic	0.562
NPHS1	O60500-1.1	A813M	Neutral	0.389
NPHS1	O60500-1.1	A813N	Neutral	0.177
NPHS1	O60500-1.1	A813P	Neutral	0.117
NPHS1	O60500-1.1	A813Q	Neutral	0.218
NPHS1	O60500-1.1	A813R	Pathogenic	0.667
NPHS1	O60500-1.1	A813S	Neutral	0.152
NPHS1	O60500-1.1	A813T	Neutral	0.111
NPHS1	O60500-1.1	A813V	Neutral	0.372
NPHS1	O60500-1.1	A813W	Pathogenic	0.766
NPHS1	O60500-1.1	A813Y	Neutral	0.299
NPHS1	O60500-1.1	Y814A	Pathogenic	0.999
NPHS1	O60500-1.1	Y814C	Pathogenic	0.996
NPHS1	O60500-1.1	Y814D	Pathogenic	1.0
NPHS1	O60500-1.1	Y814E	Pathogenic	0.999
NPHS1	O60500-1.1	Y814F	Pathogenic	1.0
NPHS1	O60500-1.1	Y814G	Pathogenic	0.999
NPHS1	O60500-1.1	Y814H	Pathogenic	1.0
NPHS1	O60500-1.1	Y814I	Pathogenic	0.998
NPHS1	O60500-1.1	Y814K	Pathogenic	0.999
NPHS1	O60500-1.1	Y814L	Pathogenic	0.998
NPHS1	O60500-1.1	Y814M	Pathogenic	0.996
NPHS1	O60500-1.1	Y814N	Pathogenic	1.0
NPHS1	O60500-1.1	Y814P	Pathogenic	0.996
NPHS1	O60500-1.1	Y814Q	Pathogenic	0.999
NPHS1	O60500-1.1	Y814R	Pathogenic	0.999
NPHS1	O60500-1.1	Y814S	Pathogenic	0.999
NPHS1	O60500-1.1	Y814T	Pathogenic	0.998
NPHS1	O60500-1.1	Y814V	Pathogenic	0.997
NPHS1	O60500-1.1	Y814W	Pathogenic	1.0
NPHS1	O60500-1.1	Q815A	Pathogenic	0.917
NPHS1	O60500-1.1	Q815C	Pathogenic	0.896
NPHS1	O60500-1.1	Q815D	Pathogenic	0.906
NPHS1	O60500-1.1	Q815E	Pathogenic	0.92
NPHS1	O60500-1.1	Q815F	Pathogenic	0.961
NPHS1	O60500-1.1	Q815G	Pathogenic	0.88
NPHS1	O60500-1.1	Q815H	Pathogenic	0.821
NPHS1	O60500-1.1	Q815I	Pathogenic	0.95
NPHS1	O60500-1.1	Q815K	Pathogenic	0.95
NPHS1	O60500-1.1	Q815L	Pathogenic	0.961
NPHS1	O60500-1.1	Q815M	Pathogenic	0.964
NPHS1	O60500-1.1	Q815N	Pathogenic	0.87
NPHS1	O60500-1.1	Q815P	Pathogenic	0.922
NPHS1	O60500-1.1	Q815R	Pathogenic	0.964
NPHS1	O60500-1.1	Q815S	Pathogenic	0.895
NPHS1	O60500-1.1	Q815T	Pathogenic	0.847
NPHS1	O60500-1.1	Q815V	Pathogenic	0.921
NPHS1	O60500-1.1	Q815W	Pathogenic	0.993
NPHS1	O60500-1.1	Q815Y	Pathogenic	0.948
NPHS1	O60500-1.1	C816A	Pathogenic	0.985
NPHS1	O60500-1.1	C816D	Pathogenic	0.986
NPHS1	O60500-1.1	C816E	Pathogenic	0.983
NPHS1	O60500-1.1	C816F	Pathogenic	0.986
NPHS1	O60500-1.1	C816G	Pathogenic	0.98
NPHS1	O60500-1.1	C816H	Pathogenic	0.971
NPHS1	O60500-1.1	C816I	Pathogenic	0.988
NPHS1	O60500-1.1	C816K	Pathogenic	0.996
NPHS1	O60500-1.1	C816L	Pathogenic	0.986
NPHS1	O60500-1.1	C816M	Pathogenic	0.973
NPHS1	O60500-1.1	C816N	Pathogenic	0.984
NPHS1	O60500-1.1	C816P	Pathogenic	0.88
NPHS1	O60500-1.1	C816Q	Pathogenic	0.981
NPHS1	O60500-1.1	C816R	Pathogenic	0.997
NPHS1	O60500-1.1	C816S	Pathogenic	0.984
NPHS1	O60500-1.1	C816T	Pathogenic	0.972
NPHS1	O60500-1.1	C816V	Pathogenic	0.957
NPHS1	O60500-1.1	C816W	Pathogenic	0.996
NPHS1	O60500-1.1	C816Y	Pathogenic	0.962
NPHS1	O60500-1.1	I817A	Pathogenic	0.83
NPHS1	O60500-1.1	I817C	Pathogenic	0.534
NPHS1	O60500-1.1	I817D	Pathogenic	0.861
NPHS1	O60500-1.1	I817E	Pathogenic	0.769
NPHS1	O60500-1.1	I817F	Neutral	0.214
NPHS1	O60500-1.1	I817G	Pathogenic	0.785
NPHS1	O60500-1.1	I817H	Neutral	0.461
NPHS1	O60500-1.1	I817K	Pathogenic	0.837
NPHS1	O60500-1.1	I817L	Neutral	0.347
NPHS1	O60500-1.1	I817M	Neutral	0.417
NPHS1	O60500-1.1	I817N	Pathogenic	0.811
NPHS1	O60500-1.1	I817P	Neutral	0.41
NPHS1	O60500-1.1	I817Q	Pathogenic	0.614
NPHS1	O60500-1.1	I817R	Pathogenic	0.877
NPHS1	O60500-1.1	I817S	Pathogenic	0.826
NPHS1	O60500-1.1	I817T	Pathogenic	0.741
NPHS1	O60500-1.1	I817V	Pathogenic	0.718
NPHS1	O60500-1.1	I817W	Neutral	0.232
NPHS1	O60500-1.1	I817Y	Neutral	0.419
NPHS1	O60500-1.1	V818A	Pathogenic	0.975
NPHS1	O60500-1.1	V818C	Pathogenic	0.86
NPHS1	O60500-1.1	V818D	Pathogenic	0.971
NPHS1	O60500-1.1	V818E	Pathogenic	0.97
NPHS1	O60500-1.1	V818F	Pathogenic	0.93
NPHS1	O60500-1.1	V818G	Pathogenic	0.967
NPHS1	O60500-1.1	V818H	Pathogenic	0.895
NPHS1	O60500-1.1	V818I	Pathogenic	0.981
NPHS1	O60500-1.1	V818K	Pathogenic	0.99
NPHS1	O60500-1.1	V818L	Pathogenic	0.952
NPHS1	O60500-1.1	V818M	Pathogenic	0.908
NPHS1	O60500-1.1	V818N	Pathogenic	0.958
NPHS1	O60500-1.1	V818P	Pathogenic	0.848
NPHS1	O60500-1.1	V818Q	Pathogenic	0.951
NPHS1	O60500-1.1	V818R	Pathogenic	0.989
NPHS1	O60500-1.1	V818S	Pathogenic	0.962
NPHS1	O60500-1.1	V818T	Pathogenic	0.958
NPHS1	O60500-1.1	V818W	Pathogenic	0.958
NPHS1	O60500-1.1	V818Y	Pathogenic	0.905
NPHS1	O60500-1.1	D819A	Pathogenic	0.992
NPHS1	O60500-1.1	D819C	Pathogenic	0.993
NPHS1	O60500-1.1	D819E	Pathogenic	0.992
NPHS1	O60500-1.1	D819F	Pathogenic	0.999
NPHS1	O60500-1.1	D819G	Pathogenic	0.995
NPHS1	O60500-1.1	D819H	Pathogenic	0.994
NPHS1	O60500-1.1	D819I	Pathogenic	0.999
NPHS1	O60500-1.1	D819K	Pathogenic	0.988
NPHS1	O60500-1.1	D819L	Pathogenic	0.998
NPHS1	O60500-1.1	D819M	Pathogenic	0.998
NPHS1	O60500-1.1	D819N	Pathogenic	0.986
NPHS1	O60500-1.1	D819P	Pathogenic	0.995
NPHS1	O60500-1.1	D819Q	Pathogenic	0.992
NPHS1	O60500-1.1	D819R	Pathogenic	0.987
NPHS1	O60500-1.1	D819S	Pathogenic	0.993
NPHS1	O60500-1.1	D819T	Pathogenic	0.99
NPHS1	O60500-1.1	D819V	Pathogenic	0.996
NPHS1	O60500-1.1	D819W	Pathogenic	1.0
NPHS1	O60500-1.1	D819Y	Pathogenic	0.998
NPHS1	O60500-1.1	N820A	Pathogenic	0.998
NPHS1	O60500-1.1	N820C	Pathogenic	0.998
NPHS1	O60500-1.1	N820D	Pathogenic	0.997
NPHS1	O60500-1.1	N820E	Pathogenic	0.995
NPHS1	O60500-1.1	N820F	Pathogenic	1.0
NPHS1	O60500-1.1	N820G	Pathogenic	0.999
NPHS1	O60500-1.1	N820H	Pathogenic	0.999
NPHS1	O60500-1.1	N820I	Pathogenic	1.0
NPHS1	O60500-1.1	N820K	Pathogenic	0.998
NPHS1	O60500-1.1	N820L	Pathogenic	1.0
NPHS1	O60500-1.1	N820M	Pathogenic	0.999
NPHS1	O60500-1.1	N820P	Pathogenic	0.998
NPHS1	O60500-1.1	N820Q	Pathogenic	0.997
NPHS1	O60500-1.1	N820R	Pathogenic	0.999
NPHS1	O60500-1.1	N820S	Pathogenic	0.999
NPHS1	O60500-1.1	N820T	Pathogenic	0.998
NPHS1	O60500-1.1	N820V	Pathogenic	0.999
NPHS1	O60500-1.1	N820W	Pathogenic	1.0
NPHS1	O60500-1.1	N820Y	Pathogenic	0.999
NPHS1	O60500-1.1	G821A	Pathogenic	0.973
NPHS1	O60500-1.1	G821C	Pathogenic	0.979
NPHS1	O60500-1.1	G821D	Pathogenic	0.988
NPHS1	O60500-1.1	G821E	Pathogenic	0.986
NPHS1	O60500-1.1	G821F	Pathogenic	0.998
NPHS1	O60500-1.1	G821H	Pathogenic	0.976
NPHS1	O60500-1.1	G821I	Pathogenic	0.996
NPHS1	O60500-1.1	G821K	Pathogenic	0.996
NPHS1	O60500-1.1	G821L	Pathogenic	0.996
NPHS1	O60500-1.1	G821M	Pathogenic	0.994
NPHS1	O60500-1.1	G821N	Pathogenic	0.991
NPHS1	O60500-1.1	G821P	Pathogenic	0.981
NPHS1	O60500-1.1	G821Q	Pathogenic	0.977
NPHS1	O60500-1.1	G821R	Pathogenic	0.997
NPHS1	O60500-1.1	G821S	Pathogenic	0.965
NPHS1	O60500-1.1	G821T	Pathogenic	0.965
NPHS1	O60500-1.1	G821V	Pathogenic	0.99
NPHS1	O60500-1.1	G821W	Pathogenic	1.0
NPHS1	O60500-1.1	G821Y	Pathogenic	0.994
NPHS1	O60500-1.1	V822A	Pathogenic	0.876
NPHS1	O60500-1.1	V822C	Pathogenic	0.526
NPHS1	O60500-1.1	V822D	Pathogenic	0.857
NPHS1	O60500-1.1	V822E	Pathogenic	0.853
NPHS1	O60500-1.1	V822F	Pathogenic	0.704
NPHS1	O60500-1.1	V822G	Pathogenic	0.841
NPHS1	O60500-1.1	V822H	Pathogenic	0.606
NPHS1	O60500-1.1	V822I	Pathogenic	0.903
NPHS1	O60500-1.1	V822K	Pathogenic	0.948
NPHS1	O60500-1.1	V822L	Pathogenic	0.782
NPHS1	O60500-1.1	V822M	Pathogenic	0.64
NPHS1	O60500-1.1	V822N	Pathogenic	0.806
NPHS1	O60500-1.1	V822P	Pathogenic	0.501
NPHS1	O60500-1.1	V822Q	Pathogenic	0.779
NPHS1	O60500-1.1	V822R	Pathogenic	0.944
NPHS1	O60500-1.1	V822S	Pathogenic	0.822
NPHS1	O60500-1.1	V822T	Pathogenic	0.805
NPHS1	O60500-1.1	V822W	Pathogenic	0.805
NPHS1	O60500-1.1	V822Y	Pathogenic	0.632
NPHS1	O60500-1.1	A823C	Neutral	0.351
NPHS1	O60500-1.1	A823D	Neutral	0.333
NPHS1	O60500-1.1	A823E	Neutral	0.483
NPHS1	O60500-1.1	A823F	Pathogenic	0.72
NPHS1	O60500-1.1	A823G	Neutral	0.239
NPHS1	O60500-1.1	A823H	Neutral	0.198
NPHS1	O60500-1.1	A823I	Pathogenic	0.751
NPHS1	O60500-1.1	A823K	Pathogenic	0.745
NPHS1	O60500-1.1	A823L	Pathogenic	0.722
NPHS1	O60500-1.1	A823M	Pathogenic	0.563
NPHS1	O60500-1.1	A823N	Neutral	0.304
NPHS1	O60500-1.1	A823P	Neutral	0.212
NPHS1	O60500-1.1	A823Q	Neutral	0.361
NPHS1	O60500-1.1	A823R	Pathogenic	0.802
NPHS1	O60500-1.1	A823S	Neutral	0.266
NPHS1	O60500-1.1	A823T	Neutral	0.202
NPHS1	O60500-1.1	A823V	Pathogenic	0.546
NPHS1	O60500-1.1	A823W	Pathogenic	0.869
NPHS1	O60500-1.1	A823Y	Neutral	0.463
NPHS1	O60500-1.1	P824A	Pathogenic	0.898
NPHS1	O60500-1.1	P824C	Pathogenic	0.67
NPHS1	O60500-1.1	P824D	Pathogenic	0.963
NPHS1	O60500-1.1	P824E	Pathogenic	0.97
NPHS1	O60500-1.1	P824F	Pathogenic	0.923
NPHS1	O60500-1.1	P824G	Pathogenic	0.936
NPHS1	O60500-1.1	P824H	Pathogenic	0.896
NPHS1	O60500-1.1	P824I	Pathogenic	0.933
NPHS1	O60500-1.1	P824K	Pathogenic	0.99
NPHS1	O60500-1.1	P824L	Pathogenic	0.923
NPHS1	O60500-1.1	P824M	Pathogenic	0.899
NPHS1	O60500-1.1	P824N	Pathogenic	0.939
NPHS1	O60500-1.1	P824Q	Pathogenic	0.952
NPHS1	O60500-1.1	P824R	Pathogenic	0.99
NPHS1	O60500-1.1	P824S	Pathogenic	0.927
NPHS1	O60500-1.1	P824T	Pathogenic	0.855
NPHS1	O60500-1.1	P824V	Pathogenic	0.848
NPHS1	O60500-1.1	P824W	Pathogenic	0.979
NPHS1	O60500-1.1	P824Y	Pathogenic	0.856
NPHS1	O60500-1.1	P825A	Pathogenic	0.572
NPHS1	O60500-1.1	P825C	Neutral	0.236
NPHS1	O60500-1.1	P825D	Pathogenic	0.798
NPHS1	O60500-1.1	P825E	Pathogenic	0.832
NPHS1	O60500-1.1	P825F	Pathogenic	0.644
NPHS1	O60500-1.1	P825G	Pathogenic	0.69
NPHS1	O60500-1.1	P825H	Pathogenic	0.567
NPHS1	O60500-1.1	P825I	Pathogenic	0.68
NPHS1	O60500-1.1	P825K	Pathogenic	0.939
NPHS1	O60500-1.1	P825L	Pathogenic	0.646
NPHS1	O60500-1.1	P825M	Pathogenic	0.575
NPHS1	O60500-1.1	P825N	Pathogenic	0.699
NPHS1	O60500-1.1	P825Q	Pathogenic	0.75
NPHS1	O60500-1.1	P825R	Pathogenic	0.935
NPHS1	O60500-1.1	P825S	Pathogenic	0.66
NPHS1	O60500-1.1	P825T	Neutral	0.474
NPHS1	O60500-1.1	P825V	Neutral	0.458
NPHS1	O60500-1.1	P825W	Pathogenic	0.875
NPHS1	O60500-1.1	P825Y	Neutral	0.475
NPHS1	O60500-1.1	A826C	Pathogenic	0.935
NPHS1	O60500-1.1	A826D	Pathogenic	0.93
NPHS1	O60500-1.1	A826E	Pathogenic	0.961
NPHS1	O60500-1.1	A826F	Pathogenic	0.986
NPHS1	O60500-1.1	A826G	Pathogenic	0.893
NPHS1	O60500-1.1	A826H	Pathogenic	0.867
NPHS1	O60500-1.1	A826I	Pathogenic	0.988
NPHS1	O60500-1.1	A826K	Pathogenic	0.987
NPHS1	O60500-1.1	A826L	Pathogenic	0.986
NPHS1	O60500-1.1	A826M	Pathogenic	0.972
NPHS1	O60500-1.1	A826N	Pathogenic	0.921
NPHS1	O60500-1.1	A826P	Pathogenic	0.877
NPHS1	O60500-1.1	A826Q	Pathogenic	0.937
NPHS1	O60500-1.1	A826R	Pathogenic	0.991
NPHS1	O60500-1.1	A826S	Pathogenic	0.906
NPHS1	O60500-1.1	A826T	Pathogenic	0.87
NPHS1	O60500-1.1	A826V	Pathogenic	0.97
NPHS1	O60500-1.1	A826W	Pathogenic	0.994
NPHS1	O60500-1.1	A826Y	Pathogenic	0.958
NPHS1	O60500-1.1	R827A	Pathogenic	0.969
NPHS1	O60500-1.1	R827C	Pathogenic	0.961
NPHS1	O60500-1.1	R827D	Pathogenic	0.705
NPHS1	O60500-1.1	R827E	Pathogenic	0.809
NPHS1	O60500-1.1	R827F	Pathogenic	0.962
NPHS1	O60500-1.1	R827G	Pathogenic	0.954
NPHS1	O60500-1.1	R827H	Pathogenic	0.915
NPHS1	O60500-1.1	R827I	Pathogenic	0.971
NPHS1	O60500-1.1	R827K	Pathogenic	0.751
NPHS1	O60500-1.1	R827L	Pathogenic	0.977
NPHS1	O60500-1.1	R827M	Pathogenic	0.97
NPHS1	O60500-1.1	R827N	Pathogenic	0.859
NPHS1	O60500-1.1	R827P	Pathogenic	0.957
NPHS1	O60500-1.1	R827Q	Pathogenic	0.913
NPHS1	O60500-1.1	R827S	Pathogenic	0.942
NPHS1	O60500-1.1	R827T	Pathogenic	0.94
NPHS1	O60500-1.1	R827V	Pathogenic	0.957
NPHS1	O60500-1.1	R827W	Pathogenic	0.982
NPHS1	O60500-1.1	R827Y	Pathogenic	0.906
NPHS1	O60500-1.1	R828A	Neutral	0.092
NPHS1	O60500-1.1	R828C	Neutral	0.073
NPHS1	O60500-1.1	R828D	Neutral	0.008
NPHS1	O60500-1.1	R828E	Neutral	0.013
NPHS1	O60500-1.1	R828F	Neutral	0.076
NPHS1	O60500-1.1	R828G	Neutral	0.063
NPHS1	O60500-1.1	R828H	Neutral	0.034
NPHS1	O60500-1.1	R828I	Neutral	0.099
NPHS1	O60500-1.1	R828K	Neutral	0.01
NPHS1	O60500-1.1	R828L	Neutral	0.123
NPHS1	O60500-1.1	R828M	Neutral	0.094
NPHS1	O60500-1.1	R828N	Neutral	0.019
NPHS1	O60500-1.1	R828P	Neutral	0.068
NPHS1	O60500-1.1	R828Q	Neutral	0.033
NPHS1	O60500-1.1	R828S	Neutral	0.05
NPHS1	O60500-1.1	R828T	Neutral	0.048
NPHS1	O60500-1.1	R828V	Neutral	0.067
NPHS1	O60500-1.1	R828W	Neutral	0.147
NPHS1	O60500-1.1	R828Y	Neutral	0.03
NPHS1	O60500-1.1	L829A	Pathogenic	0.624
NPHS1	O60500-1.1	L829C	Neutral	0.28
NPHS1	O60500-1.1	L829D	Pathogenic	0.585
NPHS1	O60500-1.1	L829E	Pathogenic	0.531
NPHS1	O60500-1.1	L829F	Neutral	0.107
NPHS1	O60500-1.1	L829G	Pathogenic	0.553
NPHS1	O60500-1.1	L829H	Neutral	0.225
NPHS1	O60500-1.1	L829I	Neutral	0.173
NPHS1	O60500-1.1	L829K	Pathogenic	0.721
NPHS1	O60500-1.1	L829M	Neutral	0.266
NPHS1	O60500-1.1	L829N	Pathogenic	0.593
NPHS1	O60500-1.1	L829P	Neutral	0.19
NPHS1	O60500-1.1	L829Q	Neutral	0.446
NPHS1	O60500-1.1	L829R	Pathogenic	0.782
NPHS1	O60500-1.1	L829S	Pathogenic	0.617
NPHS1	O60500-1.1	L829T	Neutral	0.492
NPHS1	O60500-1.1	L829V	Neutral	0.28
NPHS1	O60500-1.1	L829W	Neutral	0.172
NPHS1	O60500-1.1	L829Y	Neutral	0.196
NPHS1	O60500-1.1	L830A	Neutral	0.005
NPHS1	O60500-1.1	L830C	Neutral	0.001
NPHS1	O60500-1.1	L830D	Neutral	0.004
NPHS1	O60500-1.1	L830E	Neutral	0.003
NPHS1	O60500-1.1	L830F	Neutral	0.0
NPHS1	O60500-1.1	L830G	Neutral	0.004
NPHS1	O60500-1.1	L830H	Neutral	0.001
NPHS1	O60500-1.1	L830I	Neutral	0.001
NPHS1	O60500-1.1	L830K	Neutral	0.008
NPHS1	O60500-1.1	L830M	Neutral	0.001
NPHS1	O60500-1.1	L830N	Neutral	0.005
NPHS1	O60500-1.1	L830P	Neutral	0.001
NPHS1	O60500-1.1	L830Q	Neutral	0.002
NPHS1	O60500-1.1	L830R	Neutral	0.011
NPHS1	O60500-1.1	L830S	Neutral	0.005
NPHS1	O60500-1.1	L830T	Neutral	0.003
NPHS1	O60500-1.1	L830V	Neutral	0.001
NPHS1	O60500-1.1	L830W	Neutral	0.001
NPHS1	O60500-1.1	L830Y	Neutral	0.001
NPHS1	O60500-1.1	R831A	Pathogenic	0.997
NPHS1	O60500-1.1	R831C	Pathogenic	0.996
NPHS1	O60500-1.1	R831D	Pathogenic	0.963
NPHS1	O60500-1.1	R831E	Pathogenic	0.979
NPHS1	O60500-1.1	R831F	Pathogenic	0.996
NPHS1	O60500-1.1	R831G	Pathogenic	0.996
NPHS1	O60500-1.1	R831H	Pathogenic	0.991
NPHS1	O60500-1.1	R831I	Pathogenic	0.997
NPHS1	O60500-1.1	R831K	Pathogenic	0.97
NPHS1	O60500-1.1	R831L	Pathogenic	0.998
NPHS1	O60500-1.1	R831M	Pathogenic	0.997
NPHS1	O60500-1.1	R831N	Pathogenic	0.985
NPHS1	O60500-1.1	R831P	Pathogenic	0.996
NPHS1	O60500-1.1	R831Q	Pathogenic	0.991
NPHS1	O60500-1.1	R831S	Pathogenic	0.994
NPHS1	O60500-1.1	R831T	Pathogenic	0.994
NPHS1	O60500-1.1	R831V	Pathogenic	0.996
NPHS1	O60500-1.1	R831W	Pathogenic	0.998
NPHS1	O60500-1.1	R831Y	Pathogenic	0.99
NPHS1	O60500-1.1	L832A	Pathogenic	0.996
NPHS1	O60500-1.1	L832C	Pathogenic	0.984
NPHS1	O60500-1.1	L832D	Pathogenic	0.996
NPHS1	O60500-1.1	L832E	Pathogenic	0.994
NPHS1	O60500-1.1	L832F	Pathogenic	0.95
NPHS1	O60500-1.1	L832G	Pathogenic	0.995
NPHS1	O60500-1.1	L832H	Pathogenic	0.979
NPHS1	O60500-1.1	L832I	Pathogenic	0.971
NPHS1	O60500-1.1	L832K	Pathogenic	0.998
NPHS1	O60500-1.1	L832M	Pathogenic	0.983
NPHS1	O60500-1.1	L832N	Pathogenic	0.996
NPHS1	O60500-1.1	L832P	Pathogenic	0.974
NPHS1	O60500-1.1	L832Q	Pathogenic	0.992
NPHS1	O60500-1.1	L832R	Pathogenic	0.998
NPHS1	O60500-1.1	L832S	Pathogenic	0.996
NPHS1	O60500-1.1	L832T	Pathogenic	0.993
NPHS1	O60500-1.1	L832V	Pathogenic	0.984
NPHS1	O60500-1.1	L832W	Pathogenic	0.97
NPHS1	O60500-1.1	L832Y	Pathogenic	0.975
NPHS1	O60500-1.1	V833A	Pathogenic	0.951
NPHS1	O60500-1.1	V833C	Pathogenic	0.753
NPHS1	O60500-1.1	V833D	Pathogenic	0.943
NPHS1	O60500-1.1	V833E	Pathogenic	0.941
NPHS1	O60500-1.1	V833F	Pathogenic	0.867
NPHS1	O60500-1.1	V833G	Pathogenic	0.936
NPHS1	O60500-1.1	V833H	Pathogenic	0.808
NPHS1	O60500-1.1	V833I	Pathogenic	0.962
NPHS1	O60500-1.1	V833K	Pathogenic	0.98
NPHS1	O60500-1.1	V833L	Pathogenic	0.908
NPHS1	O60500-1.1	V833M	Pathogenic	0.83
NPHS1	O60500-1.1	V833N	Pathogenic	0.92
NPHS1	O60500-1.1	V833P	Pathogenic	0.734
NPHS1	O60500-1.1	V833Q	Pathogenic	0.906
NPHS1	O60500-1.1	V833R	Pathogenic	0.979
NPHS1	O60500-1.1	V833S	Pathogenic	0.927
NPHS1	O60500-1.1	V833T	Pathogenic	0.919
NPHS1	O60500-1.1	V833W	Pathogenic	0.919
NPHS1	O60500-1.1	V833Y	Pathogenic	0.825
NPHS1	O60500-1.1	V834A	Pathogenic	0.987
NPHS1	O60500-1.1	V834C	Pathogenic	0.92
NPHS1	O60500-1.1	V834D	Pathogenic	0.984
NPHS1	O60500-1.1	V834E	Pathogenic	0.984
NPHS1	O60500-1.1	V834F	Pathogenic	0.961
NPHS1	O60500-1.1	V834G	Pathogenic	0.982
NPHS1	O60500-1.1	V834H	Pathogenic	0.941
NPHS1	O60500-1.1	V834I	Pathogenic	0.99
NPHS1	O60500-1.1	V834K	Pathogenic	0.995
NPHS1	O60500-1.1	V834L	Pathogenic	0.974
NPHS1	O60500-1.1	V834M	Pathogenic	0.949
NPHS1	O60500-1.1	V834N	Pathogenic	0.977
NPHS1	O60500-1.1	V834P	Pathogenic	0.912
NPHS1	O60500-1.1	V834Q	Pathogenic	0.973
NPHS1	O60500-1.1	V834R	Pathogenic	0.994
NPHS1	O60500-1.1	V834S	Pathogenic	0.98
NPHS1	O60500-1.1	V834T	Pathogenic	0.977
NPHS1	O60500-1.1	V834W	Pathogenic	0.977
NPHS1	O60500-1.1	V834Y	Pathogenic	0.947
NPHS1	O60500-1.1	R835A	Pathogenic	0.984
NPHS1	O60500-1.1	R835C	Pathogenic	0.979
NPHS1	O60500-1.1	R835D	Pathogenic	0.822
NPHS1	O60500-1.1	R835E	Pathogenic	0.891
NPHS1	O60500-1.1	R835F	Pathogenic	0.98
NPHS1	O60500-1.1	R835G	Pathogenic	0.976
NPHS1	O60500-1.1	R835H	Pathogenic	0.954
NPHS1	O60500-1.1	R835I	Pathogenic	0.985
NPHS1	O60500-1.1	R835K	Pathogenic	0.854
NPHS1	O60500-1.1	R835L	Pathogenic	0.988
NPHS1	O60500-1.1	R835M	Pathogenic	0.984
NPHS1	O60500-1.1	R835N	Pathogenic	0.922
NPHS1	O60500-1.1	R835P	Pathogenic	0.977
NPHS1	O60500-1.1	R835Q	Pathogenic	0.953
NPHS1	O60500-1.1	R835S	Pathogenic	0.969
NPHS1	O60500-1.1	R835T	Pathogenic	0.968
NPHS1	O60500-1.1	R835V	Pathogenic	0.977
NPHS1	O60500-1.1	R835W	Pathogenic	0.99
NPHS1	O60500-1.1	R835Y	Pathogenic	0.949
NPHS1	O60500-1.1	F836A	Pathogenic	0.999
NPHS1	O60500-1.1	F836C	Pathogenic	0.995
NPHS1	O60500-1.1	F836D	Pathogenic	0.999
NPHS1	O60500-1.1	F836E	Pathogenic	0.999
NPHS1	O60500-1.1	F836G	Pathogenic	0.999
NPHS1	O60500-1.1	F836H	Pathogenic	0.998
NPHS1	O60500-1.1	F836I	Pathogenic	0.982
NPHS1	O60500-1.1	F836K	Pathogenic	0.999
NPHS1	O60500-1.1	F836L	Pathogenic	0.984
NPHS1	O60500-1.1	F836M	Pathogenic	0.992
NPHS1	O60500-1.1	F836N	Pathogenic	0.999
NPHS1	O60500-1.1	F836P	Pathogenic	0.992
NPHS1	O60500-1.1	F836Q	Pathogenic	0.998
NPHS1	O60500-1.1	F836R	Pathogenic	0.999
NPHS1	O60500-1.1	F836S	Pathogenic	0.999
NPHS1	O60500-1.1	F836T	Pathogenic	0.998
NPHS1	O60500-1.1	F836V	Pathogenic	0.993
NPHS1	O60500-1.1	F836W	Pathogenic	0.996
NPHS1	O60500-1.1	F836Y	Pathogenic	0.998
NPHS1	O60500-1.1	A837C	Neutral	0.118
NPHS1	O60500-1.1	A837D	Neutral	0.11
NPHS1	O60500-1.1	A837E	Neutral	0.188
NPHS1	O60500-1.1	A837F	Neutral	0.389
NPHS1	O60500-1.1	A837G	Neutral	0.072
NPHS1	O60500-1.1	A837H	Neutral	0.058
NPHS1	O60500-1.1	A837I	Neutral	0.428
NPHS1	O60500-1.1	A837K	Neutral	0.42
NPHS1	O60500-1.1	A837L	Neutral	0.392
NPHS1	O60500-1.1	A837M	Neutral	0.242
NPHS1	O60500-1.1	A837N	Neutral	0.098
NPHS1	O60500-1.1	A837P	Neutral	0.063
NPHS1	O60500-1.1	A837Q	Neutral	0.123
NPHS1	O60500-1.1	A837R	Pathogenic	0.502
NPHS1	O60500-1.1	A837S	Neutral	0.083
NPHS1	O60500-1.1	A837T	Neutral	0.059
NPHS1	O60500-1.1	A837V	Neutral	0.23
NPHS1	O60500-1.1	A837W	Pathogenic	0.622
NPHS1	O60500-1.1	A837Y	Neutral	0.176
NPHS1	O60500-1.1	P838A	Pathogenic	0.973
NPHS1	O60500-1.1	P838C	Pathogenic	0.892
NPHS1	O60500-1.1	P838D	Pathogenic	0.991
NPHS1	O60500-1.1	P838E	Pathogenic	0.993
NPHS1	O60500-1.1	P838F	Pathogenic	0.98
NPHS1	O60500-1.1	P838G	Pathogenic	0.984
NPHS1	O60500-1.1	P838H	Pathogenic	0.972
NPHS1	O60500-1.1	P838I	Pathogenic	0.983
NPHS1	O60500-1.1	P838K	Pathogenic	0.998
NPHS1	O60500-1.1	P838L	Pathogenic	0.98
NPHS1	O60500-1.1	P838M	Pathogenic	0.973
NPHS1	O60500-1.1	P838N	Pathogenic	0.984
NPHS1	O60500-1.1	P838Q	Pathogenic	0.988
NPHS1	O60500-1.1	P838R	Pathogenic	0.997
NPHS1	O60500-1.1	P838S	Pathogenic	0.981
NPHS1	O60500-1.1	P838T	Pathogenic	0.96
NPHS1	O60500-1.1	P838V	Pathogenic	0.958
NPHS1	O60500-1.1	P838W	Pathogenic	0.995
NPHS1	O60500-1.1	P838Y	Pathogenic	0.961
NPHS1	O60500-1.1	Q839A	Pathogenic	0.615
NPHS1	O60500-1.1	Q839C	Pathogenic	0.556
NPHS1	O60500-1.1	Q839D	Pathogenic	0.583
NPHS1	O60500-1.1	Q839E	Pathogenic	0.625
NPHS1	O60500-1.1	Q839F	Pathogenic	0.779
NPHS1	O60500-1.1	Q839G	Pathogenic	0.515
NPHS1	O60500-1.1	Q839H	Neutral	0.399
NPHS1	O60500-1.1	Q839I	Pathogenic	0.735
NPHS1	O60500-1.1	Q839K	Pathogenic	0.734
NPHS1	O60500-1.1	Q839L	Pathogenic	0.78
NPHS1	O60500-1.1	Q839M	Pathogenic	0.797
NPHS1	O60500-1.1	Q839N	Neutral	0.491
NPHS1	O60500-1.1	Q839P	Pathogenic	0.631
NPHS1	O60500-1.1	Q839R	Pathogenic	0.793
NPHS1	O60500-1.1	Q839S	Pathogenic	0.553
NPHS1	O60500-1.1	Q839T	Neutral	0.445
NPHS1	O60500-1.1	Q839V	Pathogenic	0.628
NPHS1	O60500-1.1	Q839W	Pathogenic	0.953
NPHS1	O60500-1.1	Q839Y	Pathogenic	0.725
NPHS1	O60500-1.1	V840A	Pathogenic	0.794
NPHS1	O60500-1.1	V840C	Neutral	0.377
NPHS1	O60500-1.1	V840D	Pathogenic	0.766
NPHS1	O60500-1.1	V840E	Pathogenic	0.76
NPHS1	O60500-1.1	V840F	Pathogenic	0.564
NPHS1	O60500-1.1	V840G	Pathogenic	0.742
NPHS1	O60500-1.1	V840H	Neutral	0.455
NPHS1	O60500-1.1	V840I	Pathogenic	0.835
NPHS1	O60500-1.1	V840K	Pathogenic	0.908
NPHS1	O60500-1.1	V840L	Pathogenic	0.661
NPHS1	O60500-1.1	V840M	Neutral	0.492
NPHS1	O60500-1.1	V840N	Pathogenic	0.694
NPHS1	O60500-1.1	V840P	Neutral	0.353
NPHS1	O60500-1.1	V840Q	Pathogenic	0.657
NPHS1	O60500-1.1	V840R	Pathogenic	0.902
NPHS1	O60500-1.1	V840S	Pathogenic	0.715
NPHS1	O60500-1.1	V840T	Pathogenic	0.692
NPHS1	O60500-1.1	V840W	Pathogenic	0.692
NPHS1	O60500-1.1	V840Y	Neutral	0.483
NPHS1	O60500-1.1	E841A	Neutral	0.412
NPHS1	O60500-1.1	E841C	Neutral	0.269
NPHS1	O60500-1.1	E841D	Neutral	0.282
NPHS1	O60500-1.1	E841F	Pathogenic	0.661
NPHS1	O60500-1.1	E841G	Neutral	0.317
NPHS1	O60500-1.1	E841H	Neutral	0.269
NPHS1	O60500-1.1	E841I	Pathogenic	0.606
NPHS1	O60500-1.1	E841K	Neutral	0.306
NPHS1	O60500-1.1	E841L	Pathogenic	0.569
NPHS1	O60500-1.1	E841M	Neutral	0.495
NPHS1	O60500-1.1	E841N	Neutral	0.12
NPHS1	O60500-1.1	E841P	Neutral	0.428
NPHS1	O60500-1.1	E841Q	Neutral	0.306
NPHS1	O60500-1.1	E841R	Neutral	0.291
NPHS1	O60500-1.1	E841S	Neutral	0.352
NPHS1	O60500-1.1	E841T	Neutral	0.26
NPHS1	O60500-1.1	E841V	Neutral	0.425
NPHS1	O60500-1.1	E841W	Pathogenic	0.883
NPHS1	O60500-1.1	E841Y	Neutral	0.495
NPHS1	O60500-1.1	H842A	Pathogenic	0.925
NPHS1	O60500-1.1	H842C	Pathogenic	0.935
NPHS1	O60500-1.1	H842D	Pathogenic	0.969
NPHS1	O60500-1.1	H842E	Pathogenic	0.961
NPHS1	O60500-1.1	H842F	Pathogenic	0.987
NPHS1	O60500-1.1	H842G	Pathogenic	0.948
NPHS1	O60500-1.1	H842I	Pathogenic	0.964
NPHS1	O60500-1.1	H842K	Pathogenic	0.971
NPHS1	O60500-1.1	H842L	Pathogenic	0.958
NPHS1	O60500-1.1	H842M	Pathogenic	0.944
NPHS1	O60500-1.1	H842N	Pathogenic	0.979
NPHS1	O60500-1.1	H842P	Pathogenic	0.93
NPHS1	O60500-1.1	H842Q	Pathogenic	0.922
NPHS1	O60500-1.1	H842R	Pathogenic	0.986
NPHS1	O60500-1.1	H842S	Pathogenic	0.941
NPHS1	O60500-1.1	H842T	Pathogenic	0.861
NPHS1	O60500-1.1	H842V	Pathogenic	0.929
NPHS1	O60500-1.1	H842W	Pathogenic	0.995
NPHS1	O60500-1.1	H842Y	Pathogenic	0.988
NPHS1	O60500-1.1	P843A	Pathogenic	0.749
NPHS1	O60500-1.1	P843C	Neutral	0.407
NPHS1	O60500-1.1	P843D	Pathogenic	0.898
NPHS1	O60500-1.1	P843E	Pathogenic	0.917
NPHS1	O60500-1.1	P843F	Pathogenic	0.801
NPHS1	O60500-1.1	P843G	Pathogenic	0.832
NPHS1	O60500-1.1	P843H	Pathogenic	0.745
NPHS1	O60500-1.1	P843I	Pathogenic	0.826
NPHS1	O60500-1.1	P843K	Pathogenic	0.972
NPHS1	O60500-1.1	P843L	Pathogenic	0.803
NPHS1	O60500-1.1	P843M	Pathogenic	0.751
NPHS1	O60500-1.1	P843N	Pathogenic	0.838
NPHS1	O60500-1.1	P843Q	Pathogenic	0.87
NPHS1	O60500-1.1	P843R	Pathogenic	0.97
NPHS1	O60500-1.1	P843S	Pathogenic	0.812
NPHS1	O60500-1.1	P843T	Pathogenic	0.667
NPHS1	O60500-1.1	P843V	Pathogenic	0.653
NPHS1	O60500-1.1	P843W	Pathogenic	0.94
NPHS1	O60500-1.1	P843Y	Pathogenic	0.669
NPHS1	O60500-1.1	T844A	Neutral	0.026
NPHS1	O60500-1.1	T844C	Neutral	0.03
NPHS1	O60500-1.1	T844D	Neutral	0.041
NPHS1	O60500-1.1	T844E	Neutral	0.047
NPHS1	O60500-1.1	T844F	Neutral	0.135
NPHS1	O60500-1.1	T844G	Neutral	0.025
NPHS1	O60500-1.1	T844H	Neutral	0.013
NPHS1	O60500-1.1	T844I	Neutral	0.155
NPHS1	O60500-1.1	T844K	Neutral	0.132
NPHS1	O60500-1.1	T844L	Neutral	0.136
NPHS1	O60500-1.1	T844M	Neutral	0.073
NPHS1	O60500-1.1	T844N	Neutral	0.048
NPHS1	O60500-1.1	T844P	Neutral	0.019
NPHS1	O60500-1.1	T844Q	Neutral	0.029
NPHS1	O60500-1.1	T844R	Neutral	0.175
NPHS1	O60500-1.1	T844S	Neutral	0.047
NPHS1	O60500-1.1	T844V	Neutral	0.068
NPHS1	O60500-1.1	T844W	Neutral	0.376
NPHS1	O60500-1.1	T844Y	Neutral	0.05
NPHS1	O60500-1.1	P845A	Neutral	0.26
NPHS1	O60500-1.1	P845C	Neutral	0.075
NPHS1	O60500-1.1	P845D	Pathogenic	0.509
NPHS1	O60500-1.1	P845E	Pathogenic	0.566
NPHS1	O60500-1.1	P845F	Neutral	0.322
NPHS1	O60500-1.1	P845G	Neutral	0.369
NPHS1	O60500-1.1	P845H	Neutral	0.256
NPHS1	O60500-1.1	P845I	Neutral	0.359
NPHS1	O60500-1.1	P845K	Pathogenic	0.803
NPHS1	O60500-1.1	P845L	Neutral	0.324
NPHS1	O60500-1.1	P845M	Neutral	0.262
NPHS1	O60500-1.1	P845N	Neutral	0.379
NPHS1	O60500-1.1	P845Q	Neutral	0.441
NPHS1	O60500-1.1	P845R	Pathogenic	0.792
NPHS1	O60500-1.1	P845S	Neutral	0.337
NPHS1	O60500-1.1	P845T	Neutral	0.191
NPHS1	O60500-1.1	P845V	Neutral	0.182
NPHS1	O60500-1.1	P845W	Pathogenic	0.647
NPHS1	O60500-1.1	P845Y	Neutral	0.192
NPHS1	O60500-1.1	L846A	Pathogenic	0.934
NPHS1	O60500-1.1	L846C	Pathogenic	0.767
NPHS1	O60500-1.1	L846D	Pathogenic	0.923
NPHS1	O60500-1.1	L846E	Pathogenic	0.905
NPHS1	O60500-1.1	L846F	Pathogenic	0.504
NPHS1	O60500-1.1	L846G	Pathogenic	0.913
NPHS1	O60500-1.1	L846H	Pathogenic	0.711
NPHS1	O60500-1.1	L846I	Pathogenic	0.64
NPHS1	O60500-1.1	L846K	Pathogenic	0.956
NPHS1	O60500-1.1	L846M	Pathogenic	0.754
NPHS1	O60500-1.1	L846N	Pathogenic	0.925
NPHS1	O60500-1.1	L846P	Pathogenic	0.666
NPHS1	O60500-1.1	L846Q	Pathogenic	0.872
NPHS1	O60500-1.1	L846R	Pathogenic	0.968
NPHS1	O60500-1.1	L846S	Pathogenic	0.932
NPHS1	O60500-1.1	L846T	Pathogenic	0.891
NPHS1	O60500-1.1	L846V	Pathogenic	0.767
NPHS1	O60500-1.1	L846W	Pathogenic	0.637
NPHS1	O60500-1.1	L846Y	Pathogenic	0.674
NPHS1	O60500-1.1	T847A	Neutral	0.051
NPHS1	O60500-1.1	T847C	Neutral	0.059
NPHS1	O60500-1.1	T847D	Neutral	0.08
NPHS1	O60500-1.1	T847E	Neutral	0.091
NPHS1	O60500-1.1	T847F	Neutral	0.243
NPHS1	O60500-1.1	T847G	Neutral	0.049
NPHS1	O60500-1.1	T847H	Neutral	0.026
NPHS1	O60500-1.1	T847I	Neutral	0.274
NPHS1	O60500-1.1	T847K	Neutral	0.238
NPHS1	O60500-1.1	T847L	Neutral	0.244
NPHS1	O60500-1.1	T847M	Neutral	0.139
NPHS1	O60500-1.1	T847N	Neutral	0.094
NPHS1	O60500-1.1	T847P	Neutral	0.037
NPHS1	O60500-1.1	T847Q	Neutral	0.057
NPHS1	O60500-1.1	T847R	Neutral	0.303
NPHS1	O60500-1.1	T847S	Neutral	0.091
NPHS1	O60500-1.1	T847V	Neutral	0.13
NPHS1	O60500-1.1	T847W	Pathogenic	0.553
NPHS1	O60500-1.1	T847Y	Neutral	0.097
NPHS1	O60500-1.1	K848A	Pathogenic	1.0
NPHS1	O60500-1.1	K848C	Pathogenic	1.0
NPHS1	O60500-1.1	K848D	Pathogenic	0.998
NPHS1	O60500-1.1	K848E	Pathogenic	0.999
NPHS1	O60500-1.1	K848F	Pathogenic	1.0
NPHS1	O60500-1.1	K848G	Pathogenic	1.0
NPHS1	O60500-1.1	K848H	Pathogenic	0.999
NPHS1	O60500-1.1	K848I	Pathogenic	1.0
NPHS1	O60500-1.1	K848L	Pathogenic	1.0
NPHS1	O60500-1.1	K848M	Pathogenic	1.0
NPHS1	O60500-1.1	K848N	Pathogenic	0.999
NPHS1	O60500-1.1	K848P	Pathogenic	1.0
NPHS1	O60500-1.1	K848Q	Pathogenic	0.999
NPHS1	O60500-1.1	K848R	Pathogenic	0.998
NPHS1	O60500-1.1	K848S	Pathogenic	1.0
NPHS1	O60500-1.1	K848T	Pathogenic	0.999
NPHS1	O60500-1.1	K848V	Pathogenic	1.0
NPHS1	O60500-1.1	K848W	Pathogenic	1.0
NPHS1	O60500-1.1	K848Y	Pathogenic	0.999
NPHS1	O60500-1.1	V849A	Pathogenic	0.996
NPHS1	O60500-1.1	V849C	Pathogenic	0.977
NPHS1	O60500-1.1	V849D	Pathogenic	0.996
NPHS1	O60500-1.1	V849E	Pathogenic	0.996
NPHS1	O60500-1.1	V849F	Pathogenic	0.989
NPHS1	O60500-1.1	V849G	Pathogenic	0.995
NPHS1	O60500-1.1	V849H	Pathogenic	0.983
NPHS1	O60500-1.1	V849I	Pathogenic	0.997
NPHS1	O60500-1.1	V849K	Pathogenic	0.999
NPHS1	O60500-1.1	V849L	Pathogenic	0.993
NPHS1	O60500-1.1	V849M	Pathogenic	0.986
NPHS1	O60500-1.1	V849N	Pathogenic	0.994
NPHS1	O60500-1.1	V849P	Pathogenic	0.975
NPHS1	O60500-1.1	V849Q	Pathogenic	0.993
NPHS1	O60500-1.1	V849R	Pathogenic	0.998
NPHS1	O60500-1.1	V849S	Pathogenic	0.994
NPHS1	O60500-1.1	V849T	Pathogenic	0.994
NPHS1	O60500-1.1	V849W	Pathogenic	0.994
NPHS1	O60500-1.1	V849Y	Pathogenic	0.985
NPHS1	O60500-1.1	A850C	Pathogenic	0.99
NPHS1	O60500-1.1	A850D	Pathogenic	0.989
NPHS1	O60500-1.1	A850E	Pathogenic	0.994
NPHS1	O60500-1.1	A850F	Pathogenic	0.998
NPHS1	O60500-1.1	A850G	Pathogenic	0.982
NPHS1	O60500-1.1	A850H	Pathogenic	0.977
NPHS1	O60500-1.1	A850I	Pathogenic	0.998
NPHS1	O60500-1.1	A850K	Pathogenic	0.998
NPHS1	O60500-1.1	A850L	Pathogenic	0.998
NPHS1	O60500-1.1	A850M	Pathogenic	0.996
NPHS1	O60500-1.1	A850N	Pathogenic	0.987
NPHS1	O60500-1.1	A850P	Pathogenic	0.979
NPHS1	O60500-1.1	A850Q	Pathogenic	0.99
NPHS1	O60500-1.1	A850R	Pathogenic	0.999
NPHS1	O60500-1.1	A850S	Pathogenic	0.984
NPHS1	O60500-1.1	A850T	Pathogenic	0.978
NPHS1	O60500-1.1	A850V	Pathogenic	0.995
NPHS1	O60500-1.1	A850W	Pathogenic	0.999
NPHS1	O60500-1.1	A850Y	Pathogenic	0.993
NPHS1	O60500-1.1	A851C	Neutral	0.458
NPHS1	O60500-1.1	A851D	Neutral	0.438
NPHS1	O60500-1.1	A851E	Pathogenic	0.594
NPHS1	O60500-1.1	A851F	Pathogenic	0.801
NPHS1	O60500-1.1	A851G	Neutral	0.329
NPHS1	O60500-1.1	A851H	Neutral	0.279
NPHS1	O60500-1.1	A851I	Pathogenic	0.825
NPHS1	O60500-1.1	A851K	Pathogenic	0.82
NPHS1	O60500-1.1	A851L	Pathogenic	0.802
NPHS1	O60500-1.1	A851M	Pathogenic	0.669
NPHS1	O60500-1.1	A851N	Neutral	0.406
NPHS1	O60500-1.1	A851P	Neutral	0.296
NPHS1	O60500-1.1	A851Q	Neutral	0.469
NPHS1	O60500-1.1	A851R	Pathogenic	0.864
NPHS1	O60500-1.1	A851S	Neutral	0.362
NPHS1	O60500-1.1	A851T	Neutral	0.283
NPHS1	O60500-1.1	A851V	Pathogenic	0.653
NPHS1	O60500-1.1	A851W	Pathogenic	0.912
NPHS1	O60500-1.1	A851Y	Pathogenic	0.575
NPHS1	O60500-1.1	A852C	Neutral	0.335
NPHS1	O60500-1.1	A852D	Neutral	0.317
NPHS1	O60500-1.1	A852E	Neutral	0.465
NPHS1	O60500-1.1	A852F	Pathogenic	0.705
NPHS1	O60500-1.1	A852G	Neutral	0.226
NPHS1	O60500-1.1	A852H	Neutral	0.186
NPHS1	O60500-1.1	A852I	Pathogenic	0.737
NPHS1	O60500-1.1	A852K	Pathogenic	0.731
NPHS1	O60500-1.1	A852L	Pathogenic	0.707
NPHS1	O60500-1.1	A852M	Pathogenic	0.545
NPHS1	O60500-1.1	A852N	Neutral	0.289
NPHS1	O60500-1.1	A852P	Neutral	0.2
NPHS1	O60500-1.1	A852Q	Neutral	0.344
NPHS1	O60500-1.1	A852R	Pathogenic	0.79
NPHS1	O60500-1.1	A852S	Neutral	0.252
NPHS1	O60500-1.1	A852T	Neutral	0.19
NPHS1	O60500-1.1	A852V	Pathogenic	0.528
NPHS1	O60500-1.1	A852W	Pathogenic	0.861
NPHS1	O60500-1.1	A852Y	Neutral	0.445
NPHS1	O60500-1.1	G853A	Pathogenic	0.985
NPHS1	O60500-1.1	G853C	Pathogenic	0.988
NPHS1	O60500-1.1	G853D	Pathogenic	0.993
NPHS1	O60500-1.1	G853E	Pathogenic	0.992
NPHS1	O60500-1.1	G853F	Pathogenic	0.999
NPHS1	O60500-1.1	G853H	Pathogenic	0.987
NPHS1	O60500-1.1	G853I	Pathogenic	0.998
NPHS1	O60500-1.1	G853K	Pathogenic	0.997
NPHS1	O60500-1.1	G853L	Pathogenic	0.997
NPHS1	O60500-1.1	G853M	Pathogenic	0.997
NPHS1	O60500-1.1	G853N	Pathogenic	0.995
NPHS1	O60500-1.1	G853P	Pathogenic	0.989
NPHS1	O60500-1.1	G853Q	Pathogenic	0.987
NPHS1	O60500-1.1	G853R	Pathogenic	0.998
NPHS1	O60500-1.1	G853S	Pathogenic	0.98
NPHS1	O60500-1.1	G853T	Pathogenic	0.98
NPHS1	O60500-1.1	G853V	Pathogenic	0.995
NPHS1	O60500-1.1	G853W	Pathogenic	1.0
NPHS1	O60500-1.1	G853Y	Pathogenic	0.997
NPHS1	O60500-1.1	D854A	Pathogenic	0.997
NPHS1	O60500-1.1	D854C	Pathogenic	0.997
NPHS1	O60500-1.1	D854E	Pathogenic	0.997
NPHS1	O60500-1.1	D854F	Pathogenic	1.0
NPHS1	O60500-1.1	D854G	Pathogenic	0.998
NPHS1	O60500-1.1	D854H	Pathogenic	0.997
NPHS1	O60500-1.1	D854I	Pathogenic	1.0
NPHS1	O60500-1.1	D854K	Pathogenic	0.995
NPHS1	O60500-1.1	D854L	Pathogenic	0.999
NPHS1	O60500-1.1	D854M	Pathogenic	0.999
NPHS1	O60500-1.1	D854N	Pathogenic	0.994
NPHS1	O60500-1.1	D854P	Pathogenic	0.998
NPHS1	O60500-1.1	D854Q	Pathogenic	0.997
NPHS1	O60500-1.1	D854R	Pathogenic	0.995
NPHS1	O60500-1.1	D854S	Pathogenic	0.997
NPHS1	O60500-1.1	D854T	Pathogenic	0.996
NPHS1	O60500-1.1	D854V	Pathogenic	0.998
NPHS1	O60500-1.1	D854W	Pathogenic	1.0
NPHS1	O60500-1.1	D854Y	Pathogenic	0.999
NPHS1	O60500-1.1	S855A	Neutral	0.443
NPHS1	O60500-1.1	S855C	Pathogenic	0.535
NPHS1	O60500-1.1	S855D	Pathogenic	0.558
NPHS1	O60500-1.1	S855E	Pathogenic	0.613
NPHS1	O60500-1.1	S855F	Pathogenic	0.891
NPHS1	O60500-1.1	S855G	Neutral	0.346
NPHS1	O60500-1.1	S855H	Neutral	0.409
NPHS1	O60500-1.1	S855I	Pathogenic	0.865
NPHS1	O60500-1.1	S855K	Pathogenic	0.832
NPHS1	O60500-1.1	S855L	Pathogenic	0.847
NPHS1	O60500-1.1	S855M	Pathogenic	0.804
NPHS1	O60500-1.1	S855N	Pathogenic	0.622
NPHS1	O60500-1.1	S855P	Neutral	0.461
NPHS1	O60500-1.1	S855Q	Neutral	0.49
NPHS1	O60500-1.1	S855R	Pathogenic	0.822
NPHS1	O60500-1.1	S855T	Pathogenic	0.506
NPHS1	O60500-1.1	S855V	Pathogenic	0.632
NPHS1	O60500-1.1	S855W	Pathogenic	0.955
NPHS1	O60500-1.1	S855Y	Pathogenic	0.733
NPHS1	O60500-1.1	T856A	Neutral	0.399
NPHS1	O60500-1.1	T856C	Neutral	0.437
NPHS1	O60500-1.1	T856D	Pathogenic	0.519
NPHS1	O60500-1.1	T856E	Pathogenic	0.552
NPHS1	O60500-1.1	T856F	Pathogenic	0.798
NPHS1	O60500-1.1	T856G	Neutral	0.389
NPHS1	O60500-1.1	T856H	Neutral	0.246
NPHS1	O60500-1.1	T856I	Pathogenic	0.823
NPHS1	O60500-1.1	T856K	Pathogenic	0.794
NPHS1	O60500-1.1	T856L	Pathogenic	0.8
NPHS1	O60500-1.1	T856M	Pathogenic	0.665
NPHS1	O60500-1.1	T856N	Pathogenic	0.562
NPHS1	O60500-1.1	T856P	Neutral	0.323
NPHS1	O60500-1.1	T856Q	Neutral	0.427
NPHS1	O60500-1.1	T856R	Pathogenic	0.843
NPHS1	O60500-1.1	T856S	Pathogenic	0.552
NPHS1	O60500-1.1	T856V	Pathogenic	0.649
NPHS1	O60500-1.1	T856W	Pathogenic	0.938
NPHS1	O60500-1.1	T856Y	Pathogenic	0.57
NPHS1	O60500-1.1	S857A	Pathogenic	0.874
NPHS1	O60500-1.1	S857C	Pathogenic	0.909
NPHS1	O60500-1.1	S857D	Pathogenic	0.917
NPHS1	O60500-1.1	S857E	Pathogenic	0.932
NPHS1	O60500-1.1	S857F	Pathogenic	0.986
NPHS1	O60500-1.1	S857G	Pathogenic	0.821
NPHS1	O60500-1.1	S857H	Pathogenic	0.858
NPHS1	O60500-1.1	S857I	Pathogenic	0.982
NPHS1	O60500-1.1	S857K	Pathogenic	0.977
NPHS1	O60500-1.1	S857L	Pathogenic	0.98
NPHS1	O60500-1.1	S857M	Pathogenic	0.973
NPHS1	O60500-1.1	S857N	Pathogenic	0.935
NPHS1	O60500-1.1	S857P	Pathogenic	0.881
NPHS1	O60500-1.1	S857Q	Pathogenic	0.893
NPHS1	O60500-1.1	S857R	Pathogenic	0.976
NPHS1	O60500-1.1	S857T	Pathogenic	0.899
NPHS1	O60500-1.1	S857V	Pathogenic	0.937
NPHS1	O60500-1.1	S857W	Pathogenic	0.995
NPHS1	O60500-1.1	S857Y	Pathogenic	0.96
NPHS1	O60500-1.1	S858A	Neutral	0.167
NPHS1	O60500-1.1	S858C	Neutral	0.225
NPHS1	O60500-1.1	S858D	Neutral	0.241
NPHS1	O60500-1.1	S858E	Neutral	0.285
NPHS1	O60500-1.1	S858F	Pathogenic	0.672
NPHS1	O60500-1.1	S858G	Neutral	0.117
NPHS1	O60500-1.1	S858H	Neutral	0.148
NPHS1	O60500-1.1	S858I	Pathogenic	0.618
NPHS1	O60500-1.1	S858K	Pathogenic	0.555
NPHS1	O60500-1.1	S858L	Pathogenic	0.581
NPHS1	O60500-1.1	S858M	Pathogenic	0.508
NPHS1	O60500-1.1	S858N	Neutral	0.293
NPHS1	O60500-1.1	S858P	Neutral	0.177
NPHS1	O60500-1.1	S858Q	Neutral	0.194
NPHS1	O60500-1.1	S858R	Pathogenic	0.537
NPHS1	O60500-1.1	S858T	Neutral	0.205
NPHS1	O60500-1.1	S858V	Neutral	0.301
NPHS1	O60500-1.1	S858W	Pathogenic	0.841
NPHS1	O60500-1.1	S858Y	Neutral	0.408
NPHS1	O60500-1.1	A859C	Pathogenic	0.992
NPHS1	O60500-1.1	A859D	Pathogenic	0.991
NPHS1	O60500-1.1	A859E	Pathogenic	0.995
NPHS1	O60500-1.1	A859F	Pathogenic	0.998
NPHS1	O60500-1.1	A859G	Pathogenic	0.986
NPHS1	O60500-1.1	A859H	Pathogenic	0.982
NPHS1	O60500-1.1	A859I	Pathogenic	0.999
NPHS1	O60500-1.1	A859K	Pathogenic	0.998
NPHS1	O60500-1.1	A859L	Pathogenic	0.998
NPHS1	O60500-1.1	A859M	Pathogenic	0.997
NPHS1	O60500-1.1	A859N	Pathogenic	0.99
NPHS1	O60500-1.1	A859P	Pathogenic	0.984
NPHS1	O60500-1.1	A859Q	Pathogenic	0.992
NPHS1	O60500-1.1	A859R	Pathogenic	0.999
NPHS1	O60500-1.1	A859S	Pathogenic	0.988
NPHS1	O60500-1.1	A859T	Pathogenic	0.983
NPHS1	O60500-1.1	A859V	Pathogenic	0.996
NPHS1	O60500-1.1	A859W	Pathogenic	0.999
NPHS1	O60500-1.1	A859Y	Pathogenic	0.995
NPHS1	O60500-1.1	T860A	Neutral	0.335
NPHS1	O60500-1.1	T860C	Neutral	0.371
NPHS1	O60500-1.1	T860D	Neutral	0.45
NPHS1	O60500-1.1	T860E	Neutral	0.484
NPHS1	O60500-1.1	T860F	Pathogenic	0.75
NPHS1	O60500-1.1	T860G	Neutral	0.325
NPHS1	O60500-1.1	T860H	Neutral	0.198
NPHS1	O60500-1.1	T860I	Pathogenic	0.779
NPHS1	O60500-1.1	T860K	Pathogenic	0.745
NPHS1	O60500-1.1	T860L	Pathogenic	0.752
NPHS1	O60500-1.1	T860M	Pathogenic	0.601
NPHS1	O60500-1.1	T860N	Neutral	0.493
NPHS1	O60500-1.1	T860P	Neutral	0.266
NPHS1	O60500-1.1	T860Q	Neutral	0.362
NPHS1	O60500-1.1	T860R	Pathogenic	0.803
NPHS1	O60500-1.1	T860S	Neutral	0.484
NPHS1	O60500-1.1	T860V	Pathogenic	0.584
NPHS1	O60500-1.1	T860W	Pathogenic	0.92
NPHS1	O60500-1.1	T860Y	Pathogenic	0.502
NPHS1	O60500-1.1	L861A	Pathogenic	0.984
NPHS1	O60500-1.1	L861C	Pathogenic	0.935
NPHS1	O60500-1.1	L861D	Pathogenic	0.981
NPHS1	O60500-1.1	L861E	Pathogenic	0.977
NPHS1	O60500-1.1	L861F	Pathogenic	0.816
NPHS1	O60500-1.1	L861G	Pathogenic	0.979
NPHS1	O60500-1.1	L861H	Pathogenic	0.915
NPHS1	O60500-1.1	L861I	Pathogenic	0.886
NPHS1	O60500-1.1	L861K	Pathogenic	0.99
NPHS1	O60500-1.1	L861M	Pathogenic	0.931
NPHS1	O60500-1.1	L861N	Pathogenic	0.982
NPHS1	O60500-1.1	L861P	Pathogenic	0.897
NPHS1	O60500-1.1	L861Q	Pathogenic	0.968
NPHS1	O60500-1.1	L861R	Pathogenic	0.993
NPHS1	O60500-1.1	L861S	Pathogenic	0.984
NPHS1	O60500-1.1	L861T	Pathogenic	0.973
NPHS1	O60500-1.1	L861V	Pathogenic	0.935
NPHS1	O60500-1.1	L861W	Pathogenic	0.885
NPHS1	O60500-1.1	L861Y	Pathogenic	0.901
NPHS1	O60500-1.1	H862A	Pathogenic	0.709
NPHS1	O60500-1.1	H862C	Pathogenic	0.74
NPHS1	O60500-1.1	H862D	Pathogenic	0.859
NPHS1	O60500-1.1	H862E	Pathogenic	0.829
NPHS1	O60500-1.1	H862F	Pathogenic	0.937
NPHS1	O60500-1.1	H862G	Pathogenic	0.782
NPHS1	O60500-1.1	H862I	Pathogenic	0.839
NPHS1	O60500-1.1	H862K	Pathogenic	0.869
NPHS1	O60500-1.1	H862L	Pathogenic	0.818
NPHS1	O60500-1.1	H862M	Pathogenic	0.769
NPHS1	O60500-1.1	H862N	Pathogenic	0.903
NPHS1	O60500-1.1	H862P	Pathogenic	0.723
NPHS1	O60500-1.1	H862Q	Pathogenic	0.699
NPHS1	O60500-1.1	H862R	Pathogenic	0.932
NPHS1	O60500-1.1	H862S	Pathogenic	0.757
NPHS1	O60500-1.1	H862T	Pathogenic	0.55
NPHS1	O60500-1.1	H862V	Pathogenic	0.72
NPHS1	O60500-1.1	H862W	Pathogenic	0.974
NPHS1	O60500-1.1	H862Y	Pathogenic	0.943
NPHS1	O60500-1.1	C863A	Pathogenic	0.985
NPHS1	O60500-1.1	C863D	Pathogenic	0.986
NPHS1	O60500-1.1	C863E	Pathogenic	0.983
NPHS1	O60500-1.1	C863F	Pathogenic	0.986
NPHS1	O60500-1.1	C863G	Pathogenic	0.98
NPHS1	O60500-1.1	C863H	Pathogenic	0.971
NPHS1	O60500-1.1	C863I	Pathogenic	0.988
NPHS1	O60500-1.1	C863K	Pathogenic	0.996
NPHS1	O60500-1.1	C863L	Pathogenic	0.986
NPHS1	O60500-1.1	C863M	Pathogenic	0.973
NPHS1	O60500-1.1	C863N	Pathogenic	0.984
NPHS1	O60500-1.1	C863P	Pathogenic	0.88
NPHS1	O60500-1.1	C863Q	Pathogenic	0.981
NPHS1	O60500-1.1	C863R	Pathogenic	0.997
NPHS1	O60500-1.1	C863S	Pathogenic	0.984
NPHS1	O60500-1.1	C863T	Pathogenic	0.972
NPHS1	O60500-1.1	C863V	Pathogenic	0.957
NPHS1	O60500-1.1	C863W	Pathogenic	0.996
NPHS1	O60500-1.1	C863Y	Pathogenic	0.962
NPHS1	O60500-1.1	R864A	Pathogenic	0.89
NPHS1	O60500-1.1	R864C	Pathogenic	0.864
NPHS1	O60500-1.1	R864D	Neutral	0.383
NPHS1	O60500-1.1	R864E	Pathogenic	0.523
NPHS1	O60500-1.1	R864F	Pathogenic	0.869
NPHS1	O60500-1.1	R864G	Pathogenic	0.843
NPHS1	O60500-1.1	R864H	Pathogenic	0.736
NPHS1	O60500-1.1	R864I	Pathogenic	0.898
NPHS1	O60500-1.1	R864K	Neutral	0.439
NPHS1	O60500-1.1	R864L	Pathogenic	0.918
NPHS1	O60500-1.1	R864M	Pathogenic	0.893
NPHS1	O60500-1.1	R864N	Pathogenic	0.612
NPHS1	O60500-1.1	R864P	Pathogenic	0.853
NPHS1	O60500-1.1	R864Q	Pathogenic	0.73
NPHS1	O60500-1.1	R864S	Pathogenic	0.808
NPHS1	O60500-1.1	R864T	Pathogenic	0.802
NPHS1	O60500-1.1	R864V	Pathogenic	0.852
NPHS1	O60500-1.1	R864W	Pathogenic	0.932
NPHS1	O60500-1.1	R864Y	Pathogenic	0.714
NPHS1	O60500-1.1	A865C	Pathogenic	0.98
NPHS1	O60500-1.1	A865D	Pathogenic	0.978
NPHS1	O60500-1.1	A865E	Pathogenic	0.988
NPHS1	O60500-1.1	A865F	Pathogenic	0.996
NPHS1	O60500-1.1	A865G	Pathogenic	0.966
NPHS1	O60500-1.1	A865H	Pathogenic	0.957
NPHS1	O60500-1.1	A865I	Pathogenic	0.996
NPHS1	O60500-1.1	A865K	Pathogenic	0.996
NPHS1	O60500-1.1	A865L	Pathogenic	0.996
NPHS1	O60500-1.1	A865M	Pathogenic	0.991
NPHS1	O60500-1.1	A865N	Pathogenic	0.975
NPHS1	O60500-1.1	A865P	Pathogenic	0.96
NPHS1	O60500-1.1	A865Q	Pathogenic	0.981
NPHS1	O60500-1.1	A865R	Pathogenic	0.997
NPHS1	O60500-1.1	A865S	Pathogenic	0.97
NPHS1	O60500-1.1	A865T	Pathogenic	0.958
NPHS1	O60500-1.1	A865V	Pathogenic	0.991
NPHS1	O60500-1.1	A865W	Pathogenic	0.998
NPHS1	O60500-1.1	A865Y	Pathogenic	0.987
NPHS1	O60500-1.1	R866A	Pathogenic	0.954
NPHS1	O60500-1.1	R866C	Pathogenic	0.942
NPHS1	O60500-1.1	R866D	Pathogenic	0.615
NPHS1	O60500-1.1	R866E	Pathogenic	0.739
NPHS1	O60500-1.1	R866F	Pathogenic	0.945
NPHS1	O60500-1.1	R866G	Pathogenic	0.933
NPHS1	O60500-1.1	R866H	Pathogenic	0.878
NPHS1	O60500-1.1	R866I	Pathogenic	0.958
NPHS1	O60500-1.1	R866K	Pathogenic	0.668
NPHS1	O60500-1.1	R866L	Pathogenic	0.967
NPHS1	O60500-1.1	R866M	Pathogenic	0.956
NPHS1	O60500-1.1	R866N	Pathogenic	0.802
NPHS1	O60500-1.1	R866P	Pathogenic	0.937
NPHS1	O60500-1.1	R866Q	Pathogenic	0.875
NPHS1	O60500-1.1	R866S	Pathogenic	0.916
NPHS1	O60500-1.1	R866T	Pathogenic	0.913
NPHS1	O60500-1.1	R866V	Pathogenic	0.937
NPHS1	O60500-1.1	R866W	Pathogenic	0.973
NPHS1	O60500-1.1	R866Y	Pathogenic	0.866
NPHS1	O60500-1.1	G867A	Pathogenic	0.978
NPHS1	O60500-1.1	G867C	Pathogenic	0.983
NPHS1	O60500-1.1	G867D	Pathogenic	0.99
NPHS1	O60500-1.1	G867E	Pathogenic	0.989
NPHS1	O60500-1.1	G867F	Pathogenic	0.998
NPHS1	O60500-1.1	G867H	Pathogenic	0.981
NPHS1	O60500-1.1	G867I	Pathogenic	0.997
NPHS1	O60500-1.1	G867K	Pathogenic	0.996
NPHS1	O60500-1.1	G867L	Pathogenic	0.996
NPHS1	O60500-1.1	G867M	Pathogenic	0.995
NPHS1	O60500-1.1	G867N	Pathogenic	0.993
NPHS1	O60500-1.1	G867P	Pathogenic	0.984
NPHS1	O60500-1.1	G867Q	Pathogenic	0.981
NPHS1	O60500-1.1	G867R	Pathogenic	0.997
NPHS1	O60500-1.1	G867S	Pathogenic	0.971
NPHS1	O60500-1.1	G867T	Pathogenic	0.971
NPHS1	O60500-1.1	G867V	Pathogenic	0.992
NPHS1	O60500-1.1	G867W	Pathogenic	1.0
NPHS1	O60500-1.1	G867Y	Pathogenic	0.995
NPHS1	O60500-1.1	V868A	Pathogenic	0.976
NPHS1	O60500-1.1	V868C	Pathogenic	0.865
NPHS1	O60500-1.1	V868D	Pathogenic	0.972
NPHS1	O60500-1.1	V868E	Pathogenic	0.971
NPHS1	O60500-1.1	V868F	Pathogenic	0.932
NPHS1	O60500-1.1	V868G	Pathogenic	0.968
NPHS1	O60500-1.1	V868H	Pathogenic	0.898
NPHS1	O60500-1.1	V868I	Pathogenic	0.982
NPHS1	O60500-1.1	V868K	Pathogenic	0.991
NPHS1	O60500-1.1	V868L	Pathogenic	0.954
NPHS1	O60500-1.1	V868M	Pathogenic	0.911
NPHS1	O60500-1.1	V868N	Pathogenic	0.96
NPHS1	O60500-1.1	V868P	Pathogenic	0.852
NPHS1	O60500-1.1	V868Q	Pathogenic	0.953
NPHS1	O60500-1.1	V868R	Pathogenic	0.99
NPHS1	O60500-1.1	V868S	Pathogenic	0.964
NPHS1	O60500-1.1	V868T	Pathogenic	0.96
NPHS1	O60500-1.1	V868W	Pathogenic	0.96
NPHS1	O60500-1.1	V868Y	Pathogenic	0.908
NPHS1	O60500-1.1	P869A	Pathogenic	0.978
NPHS1	O60500-1.1	P869C	Pathogenic	0.91
NPHS1	O60500-1.1	P869D	Pathogenic	0.992
NPHS1	O60500-1.1	P869E	Pathogenic	0.994
NPHS1	O60500-1.1	P869F	Pathogenic	0.983
NPHS1	O60500-1.1	P869G	Pathogenic	0.986
NPHS1	O60500-1.1	P869H	Pathogenic	0.977
NPHS1	O60500-1.1	P869I	Pathogenic	0.986
NPHS1	O60500-1.1	P869K	Pathogenic	0.998
NPHS1	O60500-1.1	P869L	Pathogenic	0.984
NPHS1	O60500-1.1	P869M	Pathogenic	0.978
NPHS1	O60500-1.1	P869N	Pathogenic	0.987
NPHS1	O60500-1.1	P869Q	Pathogenic	0.99
NPHS1	O60500-1.1	P869R	Pathogenic	0.998
NPHS1	O60500-1.1	P869S	Pathogenic	0.985
NPHS1	O60500-1.1	P869T	Pathogenic	0.967
NPHS1	O60500-1.1	P869V	Pathogenic	0.965
NPHS1	O60500-1.1	P869W	Pathogenic	0.996
NPHS1	O60500-1.1	P869Y	Pathogenic	0.968
NPHS1	O60500-1.1	N870A	Pathogenic	0.567
NPHS1	O60500-1.1	N870C	Pathogenic	0.605
NPHS1	O60500-1.1	N870D	Neutral	0.45
NPHS1	O60500-1.1	N870E	Neutral	0.353
NPHS1	O60500-1.1	N870F	Pathogenic	0.91
NPHS1	O60500-1.1	N870G	Pathogenic	0.743
NPHS1	O60500-1.1	N870H	Pathogenic	0.739
NPHS1	O60500-1.1	N870I	Pathogenic	0.888
NPHS1	O60500-1.1	N870K	Pathogenic	0.63
NPHS1	O60500-1.1	N870L	Pathogenic	0.872
NPHS1	O60500-1.1	N870M	Pathogenic	0.835
NPHS1	O60500-1.1	N870P	Pathogenic	0.584
NPHS1	O60500-1.1	N870Q	Pathogenic	0.506
NPHS1	O60500-1.1	N870R	Pathogenic	0.703
NPHS1	O60500-1.1	N870S	Pathogenic	0.693
NPHS1	O60500-1.1	N870T	Pathogenic	0.594
NPHS1	O60500-1.1	N870V	Pathogenic	0.679
NPHS1	O60500-1.1	N870W	Pathogenic	0.963
NPHS1	O60500-1.1	N870Y	Pathogenic	0.835
NPHS1	O60500-1.1	I871A	Pathogenic	0.991
NPHS1	O60500-1.1	I871C	Pathogenic	0.961
NPHS1	O60500-1.1	I871D	Pathogenic	0.993
NPHS1	O60500-1.1	I871E	Pathogenic	0.986
NPHS1	O60500-1.1	I871F	Pathogenic	0.855
NPHS1	O60500-1.1	I871G	Pathogenic	0.988
NPHS1	O60500-1.1	I871H	Pathogenic	0.949
NPHS1	O60500-1.1	I871K	Pathogenic	0.991
NPHS1	O60500-1.1	I871L	Pathogenic	0.92
NPHS1	O60500-1.1	I871M	Pathogenic	0.939
NPHS1	O60500-1.1	I871N	Pathogenic	0.989
NPHS1	O60500-1.1	I871P	Pathogenic	0.937
NPHS1	O60500-1.1	I871Q	Pathogenic	0.972
NPHS1	O60500-1.1	I871R	Pathogenic	0.994
NPHS1	O60500-1.1	I871S	Pathogenic	0.99
NPHS1	O60500-1.1	I871T	Pathogenic	0.984
NPHS1	O60500-1.1	I871V	Pathogenic	0.982
NPHS1	O60500-1.1	I871W	Pathogenic	0.867
NPHS1	O60500-1.1	I871Y	Pathogenic	0.94
NPHS1	O60500-1.1	V872A	Neutral	0.179
NPHS1	O60500-1.1	V872C	Neutral	0.033
NPHS1	O60500-1.1	V872D	Neutral	0.156
NPHS1	O60500-1.1	V872E	Neutral	0.152
NPHS1	O60500-1.1	V872F	Neutral	0.068
NPHS1	O60500-1.1	V872G	Neutral	0.14
NPHS1	O60500-1.1	V872H	Neutral	0.045
NPHS1	O60500-1.1	V872I	Neutral	0.222
NPHS1	O60500-1.1	V872K	Neutral	0.358
NPHS1	O60500-1.1	V872L	Neutral	0.099
NPHS1	O60500-1.1	V872M	Neutral	0.052
NPHS1	O60500-1.1	V872N	Neutral	0.113
NPHS1	O60500-1.1	V872P	Neutral	0.03
NPHS1	O60500-1.1	V872Q	Neutral	0.098
NPHS1	O60500-1.1	V872R	Neutral	0.342
NPHS1	O60500-1.1	V872S	Neutral	0.124
NPHS1	O60500-1.1	V872T	Neutral	0.113
NPHS1	O60500-1.1	V872W	Neutral	0.112
NPHS1	O60500-1.1	V872Y	Neutral	0.05
NPHS1	O60500-1.1	F873A	Pathogenic	1.0
NPHS1	O60500-1.1	F873C	Pathogenic	0.998
NPHS1	O60500-1.1	F873D	Pathogenic	1.0
NPHS1	O60500-1.1	F873E	Pathogenic	1.0
NPHS1	O60500-1.1	F873G	Pathogenic	1.0
NPHS1	O60500-1.1	F873H	Pathogenic	0.999
NPHS1	O60500-1.1	F873I	Pathogenic	0.994
NPHS1	O60500-1.1	F873K	Pathogenic	1.0
NPHS1	O60500-1.1	F873L	Pathogenic	0.994
NPHS1	O60500-1.1	F873M	Pathogenic	0.997
NPHS1	O60500-1.1	F873N	Pathogenic	1.0
NPHS1	O60500-1.1	F873P	Pathogenic	0.997
NPHS1	O60500-1.1	F873Q	Pathogenic	0.999
NPHS1	O60500-1.1	F873R	Pathogenic	1.0
NPHS1	O60500-1.1	F873S	Pathogenic	1.0
NPHS1	O60500-1.1	F873T	Pathogenic	0.999
NPHS1	O60500-1.1	F873V	Pathogenic	0.997
NPHS1	O60500-1.1	F873W	Pathogenic	0.999
NPHS1	O60500-1.1	F873Y	Pathogenic	0.999
NPHS1	O60500-1.1	T874A	Pathogenic	0.687
NPHS1	O60500-1.1	T874C	Pathogenic	0.719
NPHS1	O60500-1.1	T874D	Pathogenic	0.781
NPHS1	O60500-1.1	T874E	Pathogenic	0.803
NPHS1	O60500-1.1	T874F	Pathogenic	0.929
NPHS1	O60500-1.1	T874G	Pathogenic	0.677
NPHS1	O60500-1.1	T874H	Pathogenic	0.518
NPHS1	O60500-1.1	T874I	Pathogenic	0.939
NPHS1	O60500-1.1	T874K	Pathogenic	0.927
NPHS1	O60500-1.1	T874L	Pathogenic	0.929
NPHS1	O60500-1.1	T874M	Pathogenic	0.867
NPHS1	O60500-1.1	T874N	Pathogenic	0.809
NPHS1	O60500-1.1	T874P	Pathogenic	0.611
NPHS1	O60500-1.1	T874Q	Pathogenic	0.711
NPHS1	O60500-1.1	T874R	Pathogenic	0.946
NPHS1	O60500-1.1	T874S	Pathogenic	0.803
NPHS1	O60500-1.1	T874V	Pathogenic	0.859
NPHS1	O60500-1.1	T874W	Pathogenic	0.98
NPHS1	O60500-1.1	T874Y	Pathogenic	0.814
NPHS1	O60500-1.1	W875A	Pathogenic	1.0
NPHS1	O60500-1.1	W875C	Pathogenic	1.0
NPHS1	O60500-1.1	W875D	Pathogenic	1.0
NPHS1	O60500-1.1	W875E	Pathogenic	1.0
NPHS1	O60500-1.1	W875F	Pathogenic	1.0
NPHS1	O60500-1.1	W875G	Pathogenic	1.0
NPHS1	O60500-1.1	W875H	Pathogenic	1.0
NPHS1	O60500-1.1	W875I	Pathogenic	0.999
NPHS1	O60500-1.1	W875K	Pathogenic	1.0
NPHS1	O60500-1.1	W875L	Pathogenic	0.999
NPHS1	O60500-1.1	W875M	Pathogenic	1.0
NPHS1	O60500-1.1	W875N	Pathogenic	1.0
NPHS1	O60500-1.1	W875P	Pathogenic	1.0
NPHS1	O60500-1.1	W875Q	Pathogenic	1.0
NPHS1	O60500-1.1	W875R	Pathogenic	1.0
NPHS1	O60500-1.1	W875S	Pathogenic	1.0
NPHS1	O60500-1.1	W875T	Pathogenic	1.0
NPHS1	O60500-1.1	W875V	Pathogenic	1.0
NPHS1	O60500-1.1	W875Y	Pathogenic	1.0
NPHS1	O60500-1.1	T876A	Neutral	0.358
NPHS1	O60500-1.1	T876C	Neutral	0.395
NPHS1	O60500-1.1	T876D	Neutral	0.475
NPHS1	O60500-1.1	T876E	Pathogenic	0.509
NPHS1	O60500-1.1	T876F	Pathogenic	0.769
NPHS1	O60500-1.1	T876G	Neutral	0.348
NPHS1	O60500-1.1	T876H	Neutral	0.215
NPHS1	O60500-1.1	T876I	Pathogenic	0.796
NPHS1	O60500-1.1	T876K	Pathogenic	0.764
NPHS1	O60500-1.1	T876L	Pathogenic	0.77
NPHS1	O60500-1.1	T876M	Pathogenic	0.625
NPHS1	O60500-1.1	T876N	Pathogenic	0.519
NPHS1	O60500-1.1	T876P	Neutral	0.286
NPHS1	O60500-1.1	T876Q	Neutral	0.385
NPHS1	O60500-1.1	T876R	Pathogenic	0.818
NPHS1	O60500-1.1	T876S	Pathogenic	0.509
NPHS1	O60500-1.1	T876V	Pathogenic	0.608
NPHS1	O60500-1.1	T876W	Pathogenic	0.928
NPHS1	O60500-1.1	T876Y	Pathogenic	0.527
NPHS1	O60500-1.1	K877A	Pathogenic	1.0
NPHS1	O60500-1.1	K877C	Pathogenic	1.0
NPHS1	O60500-1.1	K877D	Pathogenic	0.997
NPHS1	O60500-1.1	K877E	Pathogenic	0.998
NPHS1	O60500-1.1	K877F	Pathogenic	1.0
NPHS1	O60500-1.1	K877G	Pathogenic	1.0
NPHS1	O60500-1.1	K877H	Pathogenic	0.999
NPHS1	O60500-1.1	K877I	Pathogenic	1.0
NPHS1	O60500-1.1	K877L	Pathogenic	1.0
NPHS1	O60500-1.1	K877M	Pathogenic	1.0
NPHS1	O60500-1.1	K877N	Pathogenic	0.998
NPHS1	O60500-1.1	K877P	Pathogenic	1.0
NPHS1	O60500-1.1	K877Q	Pathogenic	0.999
NPHS1	O60500-1.1	K877R	Pathogenic	0.998
NPHS1	O60500-1.1	K877S	Pathogenic	1.0
NPHS1	O60500-1.1	K877T	Pathogenic	0.999
NPHS1	O60500-1.1	K877V	Pathogenic	1.0
NPHS1	O60500-1.1	K877W	Pathogenic	1.0
NPHS1	O60500-1.1	K877Y	Pathogenic	0.999
NPHS1	O60500-1.1	N878A	Pathogenic	0.984
NPHS1	O60500-1.1	N878C	Pathogenic	0.987
NPHS1	O60500-1.1	N878D	Pathogenic	0.975
NPHS1	O60500-1.1	N878E	Pathogenic	0.963
NPHS1	O60500-1.1	N878F	Pathogenic	0.998
NPHS1	O60500-1.1	N878G	Pathogenic	0.993
NPHS1	O60500-1.1	N878H	Pathogenic	0.993
NPHS1	O60500-1.1	N878I	Pathogenic	0.997
NPHS1	O60500-1.1	N878K	Pathogenic	0.988
NPHS1	O60500-1.1	N878L	Pathogenic	0.997
NPHS1	O60500-1.1	N878M	Pathogenic	0.996
NPHS1	O60500-1.1	N878P	Pathogenic	0.985
NPHS1	O60500-1.1	N878Q	Pathogenic	0.98
NPHS1	O60500-1.1	N878R	Pathogenic	0.991
NPHS1	O60500-1.1	N878S	Pathogenic	0.991
NPHS1	O60500-1.1	N878T	Pathogenic	0.986
NPHS1	O60500-1.1	N878V	Pathogenic	0.99
NPHS1	O60500-1.1	N878W	Pathogenic	0.999
NPHS1	O60500-1.1	N878Y	Pathogenic	0.996
NPHS1	O60500-1.1	G879A	Pathogenic	0.981
NPHS1	O60500-1.1	G879C	Pathogenic	0.985
NPHS1	O60500-1.1	G879D	Pathogenic	0.992
NPHS1	O60500-1.1	G879E	Pathogenic	0.99
NPHS1	O60500-1.1	G879F	Pathogenic	0.999
NPHS1	O60500-1.1	G879H	Pathogenic	0.983
NPHS1	O60500-1.1	G879I	Pathogenic	0.997
NPHS1	O60500-1.1	G879K	Pathogenic	0.997
NPHS1	O60500-1.1	G879L	Pathogenic	0.997
NPHS1	O60500-1.1	G879M	Pathogenic	0.996
NPHS1	O60500-1.1	G879N	Pathogenic	0.994
NPHS1	O60500-1.1	G879P	Pathogenic	0.987
NPHS1	O60500-1.1	G879Q	Pathogenic	0.984
NPHS1	O60500-1.1	G879R	Pathogenic	0.998
NPHS1	O60500-1.1	G879S	Pathogenic	0.975
NPHS1	O60500-1.1	G879T	Pathogenic	0.975
NPHS1	O60500-1.1	G879V	Pathogenic	0.993
NPHS1	O60500-1.1	G879W	Pathogenic	1.0
NPHS1	O60500-1.1	G879Y	Pathogenic	0.996
NPHS1	O60500-1.1	V880A	Pathogenic	0.696
NPHS1	O60500-1.1	V880C	Neutral	0.264
NPHS1	O60500-1.1	V880D	Pathogenic	0.661
NPHS1	O60500-1.1	V880E	Pathogenic	0.653
NPHS1	O60500-1.1	V880F	Neutral	0.435
NPHS1	O60500-1.1	V880G	Pathogenic	0.631
NPHS1	O60500-1.1	V880H	Neutral	0.332
NPHS1	O60500-1.1	V880I	Pathogenic	0.75
NPHS1	O60500-1.1	V880K	Pathogenic	0.855
NPHS1	O60500-1.1	V880L	Pathogenic	0.537
NPHS1	O60500-1.1	V880M	Neutral	0.366
NPHS1	O60500-1.1	V880N	Pathogenic	0.574
NPHS1	O60500-1.1	V880P	Neutral	0.245
NPHS1	O60500-1.1	V880Q	Pathogenic	0.533
NPHS1	O60500-1.1	V880R	Pathogenic	0.846
NPHS1	O60500-1.1	V880S	Pathogenic	0.599
NPHS1	O60500-1.1	V880T	Pathogenic	0.572
NPHS1	O60500-1.1	V880W	Pathogenic	0.572
NPHS1	O60500-1.1	V880Y	Neutral	0.357
NPHS1	O60500-1.1	P881A	Neutral	0.36
NPHS1	O60500-1.1	P881C	Neutral	0.115
NPHS1	O60500-1.1	P881D	Pathogenic	0.624
NPHS1	O60500-1.1	P881E	Pathogenic	0.676
NPHS1	O60500-1.1	P881F	Neutral	0.432
NPHS1	O60500-1.1	P881G	Neutral	0.483
NPHS1	O60500-1.1	P881H	Neutral	0.355
NPHS1	O60500-1.1	P881I	Neutral	0.472
NPHS1	O60500-1.1	P881K	Pathogenic	0.867
NPHS1	O60500-1.1	P881L	Neutral	0.434
NPHS1	O60500-1.1	P881M	Neutral	0.363
NPHS1	O60500-1.1	P881N	Neutral	0.494
NPHS1	O60500-1.1	P881Q	Pathogenic	0.558
NPHS1	O60500-1.1	P881R	Pathogenic	0.859
NPHS1	O60500-1.1	P881S	Neutral	0.449
NPHS1	O60500-1.1	P881T	Neutral	0.274
NPHS1	O60500-1.1	P881V	Neutral	0.262
NPHS1	O60500-1.1	P881W	Pathogenic	0.746
NPHS1	O60500-1.1	P881Y	Neutral	0.276
NPHS1	O60500-1.1	L882A	Pathogenic	0.98
NPHS1	O60500-1.1	L882C	Pathogenic	0.918
NPHS1	O60500-1.1	L882D	Pathogenic	0.976
NPHS1	O60500-1.1	L882E	Pathogenic	0.97
NPHS1	O60500-1.1	L882F	Pathogenic	0.775
NPHS1	O60500-1.1	L882G	Pathogenic	0.973
NPHS1	O60500-1.1	L882H	Pathogenic	0.893
NPHS1	O60500-1.1	L882I	Pathogenic	0.858
NPHS1	O60500-1.1	L882K	Pathogenic	0.987
NPHS1	O60500-1.1	L882M	Pathogenic	0.913
NPHS1	O60500-1.1	L882N	Pathogenic	0.977
NPHS1	O60500-1.1	L882P	Pathogenic	0.872
NPHS1	O60500-1.1	L882Q	Pathogenic	0.959
NPHS1	O60500-1.1	L882R	Pathogenic	0.99
NPHS1	O60500-1.1	L882S	Pathogenic	0.979
NPHS1	O60500-1.1	L882T	Pathogenic	0.965
NPHS1	O60500-1.1	L882V	Pathogenic	0.918
NPHS1	O60500-1.1	L882W	Pathogenic	0.857
NPHS1	O60500-1.1	L882Y	Pathogenic	0.876
NPHS1	O60500-1.1	D883A	Pathogenic	0.99
NPHS1	O60500-1.1	D883C	Pathogenic	0.992
NPHS1	O60500-1.1	D883E	Pathogenic	0.991
NPHS1	O60500-1.1	D883F	Pathogenic	0.999
NPHS1	O60500-1.1	D883G	Pathogenic	0.993
NPHS1	O60500-1.1	D883H	Pathogenic	0.992
NPHS1	O60500-1.1	D883I	Pathogenic	0.999
NPHS1	O60500-1.1	D883K	Pathogenic	0.986
NPHS1	O60500-1.1	D883L	Pathogenic	0.998
NPHS1	O60500-1.1	D883M	Pathogenic	0.997
NPHS1	O60500-1.1	D883N	Pathogenic	0.983
NPHS1	O60500-1.1	D883P	Pathogenic	0.994
NPHS1	O60500-1.1	D883Q	Pathogenic	0.99
NPHS1	O60500-1.1	D883R	Pathogenic	0.985
NPHS1	O60500-1.1	D883S	Pathogenic	0.992
NPHS1	O60500-1.1	D883T	Pathogenic	0.988
NPHS1	O60500-1.1	D883V	Pathogenic	0.995
NPHS1	O60500-1.1	D883W	Pathogenic	1.0
NPHS1	O60500-1.1	D883Y	Pathogenic	0.997
NPHS1	O60500-1.1	L884A	Pathogenic	0.832
NPHS1	O60500-1.1	L884C	Pathogenic	0.536
NPHS1	O60500-1.1	L884D	Pathogenic	0.808
NPHS1	O60500-1.1	L884E	Pathogenic	0.771
NPHS1	O60500-1.1	L884F	Neutral	0.263
NPHS1	O60500-1.1	L884G	Pathogenic	0.787
NPHS1	O60500-1.1	L884H	Neutral	0.463
NPHS1	O60500-1.1	L884I	Neutral	0.384
NPHS1	O60500-1.1	L884K	Pathogenic	0.885
NPHS1	O60500-1.1	L884M	Pathogenic	0.518
NPHS1	O60500-1.1	L884N	Pathogenic	0.812
NPHS1	O60500-1.1	L884P	Neutral	0.412
NPHS1	O60500-1.1	L884Q	Pathogenic	0.705
NPHS1	O60500-1.1	L884R	Pathogenic	0.914
NPHS1	O60500-1.1	L884S	Pathogenic	0.827
NPHS1	O60500-1.1	L884T	Pathogenic	0.742
NPHS1	O60500-1.1	L884V	Pathogenic	0.536
NPHS1	O60500-1.1	L884W	Neutral	0.381
NPHS1	O60500-1.1	L884Y	Neutral	0.421
NPHS1	O60500-1.1	Q885A	Neutral	0.231
NPHS1	O60500-1.1	Q885C	Neutral	0.191
NPHS1	O60500-1.1	Q885D	Neutral	0.208
NPHS1	O60500-1.1	Q885E	Neutral	0.239
NPHS1	O60500-1.1	Q885F	Neutral	0.399
NPHS1	O60500-1.1	Q885G	Neutral	0.167
NPHS1	O60500-1.1	Q885H	Neutral	0.111
NPHS1	O60500-1.1	Q885I	Neutral	0.343
NPHS1	O60500-1.1	Q885K	Neutral	0.342
NPHS1	O60500-1.1	Q885L	Neutral	0.401
NPHS1	O60500-1.1	Q885M	Neutral	0.425
NPHS1	O60500-1.1	Q885N	Neutral	0.154
NPHS1	O60500-1.1	Q885P	Neutral	0.244
NPHS1	O60500-1.1	Q885R	Neutral	0.419
NPHS1	O60500-1.1	Q885S	Neutral	0.189
NPHS1	O60500-1.1	Q885T	Neutral	0.131
NPHS1	O60500-1.1	Q885V	Neutral	0.241
NPHS1	O60500-1.1	Q885W	Pathogenic	0.792
NPHS1	O60500-1.1	Q885Y	Neutral	0.331
NPHS1	O60500-1.1	D886A	Pathogenic	0.79
NPHS1	O60500-1.1	D886C	Pathogenic	0.814
NPHS1	O60500-1.1	D886E	Pathogenic	0.798
NPHS1	O60500-1.1	D886F	Pathogenic	0.973
NPHS1	O60500-1.1	D886G	Pathogenic	0.847
NPHS1	O60500-1.1	D886H	Pathogenic	0.822
NPHS1	O60500-1.1	D886I	Pathogenic	0.966
NPHS1	O60500-1.1	D886K	Pathogenic	0.715
NPHS1	O60500-1.1	D886L	Pathogenic	0.943
NPHS1	O60500-1.1	D886M	Pathogenic	0.925
NPHS1	O60500-1.1	D886N	Pathogenic	0.673
NPHS1	O60500-1.1	D886P	Pathogenic	0.857
NPHS1	O60500-1.1	D886Q	Pathogenic	0.788
NPHS1	O60500-1.1	D886R	Pathogenic	0.7
NPHS1	O60500-1.1	D886S	Pathogenic	0.813
NPHS1	O60500-1.1	D886T	Pathogenic	0.755
NPHS1	O60500-1.1	D886V	Pathogenic	0.885
NPHS1	O60500-1.1	D886W	Pathogenic	0.99
NPHS1	O60500-1.1	D886Y	Pathogenic	0.925
NPHS1	O60500-1.1	P887A	Pathogenic	0.978
NPHS1	O60500-1.1	P887C	Pathogenic	0.91
NPHS1	O60500-1.1	P887D	Pathogenic	0.992
NPHS1	O60500-1.1	P887E	Pathogenic	0.994
NPHS1	O60500-1.1	P887F	Pathogenic	0.983
NPHS1	O60500-1.1	P887G	Pathogenic	0.987
NPHS1	O60500-1.1	P887H	Pathogenic	0.977
NPHS1	O60500-1.1	P887I	Pathogenic	0.986
NPHS1	O60500-1.1	P887K	Pathogenic	0.998
NPHS1	O60500-1.1	P887L	Pathogenic	0.984
NPHS1	O60500-1.1	P887M	Pathogenic	0.978
NPHS1	O60500-1.1	P887N	Pathogenic	0.987
NPHS1	O60500-1.1	P887Q	Pathogenic	0.99
NPHS1	O60500-1.1	P887R	Pathogenic	0.998
NPHS1	O60500-1.1	P887S	Pathogenic	0.985
NPHS1	O60500-1.1	P887T	Pathogenic	0.967
NPHS1	O60500-1.1	P887V	Pathogenic	0.965
NPHS1	O60500-1.1	P887W	Pathogenic	0.996
NPHS1	O60500-1.1	P887Y	Pathogenic	0.968
NPHS1	O60500-1.1	R888A	Pathogenic	0.999
NPHS1	O60500-1.1	R888C	Pathogenic	0.999
NPHS1	O60500-1.1	R888D	Pathogenic	0.991
NPHS1	O60500-1.1	R888E	Pathogenic	0.995
NPHS1	O60500-1.1	R888F	Pathogenic	0.999
NPHS1	O60500-1.1	R888G	Pathogenic	0.999
NPHS1	O60500-1.1	R888H	Pathogenic	0.998
NPHS1	O60500-1.1	R888I	Pathogenic	0.999
NPHS1	O60500-1.1	R888K	Pathogenic	0.993
NPHS1	O60500-1.1	R888L	Pathogenic	1.0
NPHS1	O60500-1.1	R888M	Pathogenic	0.999
NPHS1	O60500-1.1	R888N	Pathogenic	0.997
NPHS1	O60500-1.1	R888P	Pathogenic	0.999
NPHS1	O60500-1.1	R888Q	Pathogenic	0.998
NPHS1	O60500-1.1	R888S	Pathogenic	0.999
NPHS1	O60500-1.1	R888T	Pathogenic	0.999
NPHS1	O60500-1.1	R888V	Pathogenic	0.999
NPHS1	O60500-1.1	R888W	Pathogenic	1.0
NPHS1	O60500-1.1	R888Y	Pathogenic	0.998
NPHS1	O60500-1.1	Y889A	Pathogenic	0.999
NPHS1	O60500-1.1	Y889C	Pathogenic	0.996
NPHS1	O60500-1.1	Y889D	Pathogenic	0.999
NPHS1	O60500-1.1	Y889E	Pathogenic	0.999
NPHS1	O60500-1.1	Y889F	Pathogenic	0.999
NPHS1	O60500-1.1	Y889G	Pathogenic	0.999
NPHS1	O60500-1.1	Y889H	Pathogenic	0.999
NPHS1	O60500-1.1	Y889I	Pathogenic	0.998
NPHS1	O60500-1.1	Y889K	Pathogenic	0.999
NPHS1	O60500-1.1	Y889L	Pathogenic	0.997
NPHS1	O60500-1.1	Y889M	Pathogenic	0.995
NPHS1	O60500-1.1	Y889N	Pathogenic	0.999
NPHS1	O60500-1.1	Y889P	Pathogenic	0.995
NPHS1	O60500-1.1	Y889Q	Pathogenic	0.999
NPHS1	O60500-1.1	Y889R	Pathogenic	0.999
NPHS1	O60500-1.1	Y889S	Pathogenic	0.999
NPHS1	O60500-1.1	Y889T	Pathogenic	0.998
NPHS1	O60500-1.1	Y889V	Pathogenic	0.997
NPHS1	O60500-1.1	Y889W	Pathogenic	1.0
NPHS1	O60500-1.1	T890A	Neutral	0.356
NPHS1	O60500-1.1	T890C	Neutral	0.392
NPHS1	O60500-1.1	T890D	Neutral	0.473
NPHS1	O60500-1.1	T890E	Pathogenic	0.506
NPHS1	O60500-1.1	T890F	Pathogenic	0.766
NPHS1	O60500-1.1	T890G	Neutral	0.345
NPHS1	O60500-1.1	T890H	Neutral	0.213
NPHS1	O60500-1.1	T890I	Pathogenic	0.794
NPHS1	O60500-1.1	T890K	Pathogenic	0.762
NPHS1	O60500-1.1	T890L	Pathogenic	0.768
NPHS1	O60500-1.1	T890M	Pathogenic	0.622
NPHS1	O60500-1.1	T890N	Pathogenic	0.516
NPHS1	O60500-1.1	T890P	Neutral	0.284
NPHS1	O60500-1.1	T890Q	Neutral	0.382
NPHS1	O60500-1.1	T890R	Pathogenic	0.816
NPHS1	O60500-1.1	T890S	Pathogenic	0.506
NPHS1	O60500-1.1	T890V	Pathogenic	0.605
NPHS1	O60500-1.1	T890W	Pathogenic	0.927
NPHS1	O60500-1.1	T890Y	Pathogenic	0.524
NPHS1	O60500-1.1	E891A	Pathogenic	0.987
NPHS1	O60500-1.1	E891C	Pathogenic	0.976
NPHS1	O60500-1.1	E891D	Pathogenic	0.977
NPHS1	O60500-1.1	E891F	Pathogenic	0.995
NPHS1	O60500-1.1	E891G	Pathogenic	0.981
NPHS1	O60500-1.1	E891H	Pathogenic	0.976
NPHS1	O60500-1.1	E891I	Pathogenic	0.994
NPHS1	O60500-1.1	E891K	Pathogenic	0.98
NPHS1	O60500-1.1	E891L	Pathogenic	0.993
NPHS1	O60500-1.1	E891M	Pathogenic	0.991
NPHS1	O60500-1.1	E891N	Pathogenic	0.937
NPHS1	O60500-1.1	E891P	Pathogenic	0.988
NPHS1	O60500-1.1	E891Q	Pathogenic	0.98
NPHS1	O60500-1.1	E891R	Pathogenic	0.978
NPHS1	O60500-1.1	E891S	Pathogenic	0.983
NPHS1	O60500-1.1	E891T	Pathogenic	0.974
NPHS1	O60500-1.1	E891V	Pathogenic	0.988
NPHS1	O60500-1.1	E891W	Pathogenic	0.999
NPHS1	O60500-1.1	E891Y	Pathogenic	0.991
NPHS1	O60500-1.1	H892A	Pathogenic	0.803
NPHS1	O60500-1.1	H892C	Pathogenic	0.826
NPHS1	O60500-1.1	H892D	Pathogenic	0.91
NPHS1	O60500-1.1	H892E	Pathogenic	0.891
NPHS1	O60500-1.1	H892F	Pathogenic	0.961
NPHS1	O60500-1.1	H892G	Pathogenic	0.857
NPHS1	O60500-1.1	H892I	Pathogenic	0.897
NPHS1	O60500-1.1	H892K	Pathogenic	0.918
NPHS1	O60500-1.1	H892L	Pathogenic	0.882
NPHS1	O60500-1.1	H892M	Pathogenic	0.848
NPHS1	O60500-1.1	H892N	Pathogenic	0.94
NPHS1	O60500-1.1	H892P	Pathogenic	0.814
NPHS1	O60500-1.1	H892Q	Pathogenic	0.795
NPHS1	O60500-1.1	H892R	Pathogenic	0.958
NPHS1	O60500-1.1	H892S	Pathogenic	0.839
NPHS1	O60500-1.1	H892T	Pathogenic	0.671
NPHS1	O60500-1.1	H892V	Pathogenic	0.812
NPHS1	O60500-1.1	H892W	Pathogenic	0.985
NPHS1	O60500-1.1	H892Y	Pathogenic	0.965
NPHS1	O60500-1.1	T893A	Pathogenic	0.795
NPHS1	O60500-1.1	T893C	Pathogenic	0.819
NPHS1	O60500-1.1	T893D	Pathogenic	0.863
NPHS1	O60500-1.1	T893E	Pathogenic	0.878
NPHS1	O60500-1.1	T893F	Pathogenic	0.959
NPHS1	O60500-1.1	T893G	Pathogenic	0.788
NPHS1	O60500-1.1	T893H	Pathogenic	0.655
NPHS1	O60500-1.1	T893I	Pathogenic	0.964
NPHS1	O60500-1.1	T893K	Pathogenic	0.957
NPHS1	O60500-1.1	T893L	Pathogenic	0.959
NPHS1	O60500-1.1	T893M	Pathogenic	0.921
NPHS1	O60500-1.1	T893N	Pathogenic	0.882
NPHS1	O60500-1.1	T893P	Pathogenic	0.736
NPHS1	O60500-1.1	T893Q	Pathogenic	0.813
NPHS1	O60500-1.1	T893R	Pathogenic	0.969
NPHS1	O60500-1.1	T893S	Pathogenic	0.878
NPHS1	O60500-1.1	T893V	Pathogenic	0.915
NPHS1	O60500-1.1	T893W	Pathogenic	0.989
NPHS1	O60500-1.1	T893Y	Pathogenic	0.886
NPHS1	O60500-1.1	Y894A	Pathogenic	0.779
NPHS1	O60500-1.1	Y894C	Neutral	0.468
NPHS1	O60500-1.1	Y894D	Pathogenic	0.87
NPHS1	O60500-1.1	Y894E	Pathogenic	0.842
NPHS1	O60500-1.1	Y894F	Pathogenic	0.871
NPHS1	O60500-1.1	Y894G	Pathogenic	0.854
NPHS1	O60500-1.1	Y894H	Pathogenic	0.872
NPHS1	O60500-1.1	Y894I	Pathogenic	0.645
NPHS1	O60500-1.1	Y894K	Pathogenic	0.83
NPHS1	O60500-1.1	Y894L	Pathogenic	0.609
NPHS1	O60500-1.1	Y894M	Neutral	0.437
NPHS1	O60500-1.1	Y894N	Pathogenic	0.873
NPHS1	O60500-1.1	Y894P	Neutral	0.427
NPHS1	O60500-1.1	Y894Q	Pathogenic	0.792
NPHS1	O60500-1.1	Y894R	Pathogenic	0.836
NPHS1	O60500-1.1	Y894S	Pathogenic	0.836
NPHS1	O60500-1.1	Y894T	Pathogenic	0.673
NPHS1	O60500-1.1	Y894V	Pathogenic	0.543
NPHS1	O60500-1.1	Y894W	Pathogenic	0.93
NPHS1	O60500-1.1	H895A	Pathogenic	0.969
NPHS1	O60500-1.1	H895C	Pathogenic	0.973
NPHS1	O60500-1.1	H895D	Pathogenic	0.987
NPHS1	O60500-1.1	H895E	Pathogenic	0.984
NPHS1	O60500-1.1	H895F	Pathogenic	0.995
NPHS1	O60500-1.1	H895G	Pathogenic	0.979
NPHS1	O60500-1.1	H895I	Pathogenic	0.985
NPHS1	O60500-1.1	H895K	Pathogenic	0.988
NPHS1	O60500-1.1	H895L	Pathogenic	0.983
NPHS1	O60500-1.1	H895M	Pathogenic	0.977
NPHS1	O60500-1.1	H895N	Pathogenic	0.992
NPHS1	O60500-1.1	H895P	Pathogenic	0.971
NPHS1	O60500-1.1	H895Q	Pathogenic	0.968
NPHS1	O60500-1.1	H895R	Pathogenic	0.994
NPHS1	O60500-1.1	H895S	Pathogenic	0.976
NPHS1	O60500-1.1	H895T	Pathogenic	0.94
NPHS1	O60500-1.1	H895V	Pathogenic	0.971
NPHS1	O60500-1.1	H895W	Pathogenic	0.998
NPHS1	O60500-1.1	H895Y	Pathogenic	0.995
NPHS1	O60500-1.1	Q896A	Pathogenic	0.644
NPHS1	O60500-1.1	Q896C	Pathogenic	0.587
NPHS1	O60500-1.1	Q896D	Pathogenic	0.613
NPHS1	O60500-1.1	Q896E	Pathogenic	0.654
NPHS1	O60500-1.1	Q896F	Pathogenic	0.8
NPHS1	O60500-1.1	Q896G	Pathogenic	0.546
NPHS1	O60500-1.1	Q896H	Neutral	0.429
NPHS1	O60500-1.1	Q896I	Pathogenic	0.759
NPHS1	O60500-1.1	Q896K	Pathogenic	0.758
NPHS1	O60500-1.1	Q896L	Pathogenic	0.801
NPHS1	O60500-1.1	Q896M	Pathogenic	0.817
NPHS1	O60500-1.1	Q896N	Pathogenic	0.523
NPHS1	O60500-1.1	Q896P	Pathogenic	0.66
NPHS1	O60500-1.1	Q896R	Pathogenic	0.813
NPHS1	O60500-1.1	Q896S	Pathogenic	0.584
NPHS1	O60500-1.1	Q896T	Neutral	0.476
NPHS1	O60500-1.1	Q896V	Pathogenic	0.657
NPHS1	O60500-1.1	Q896W	Pathogenic	0.958
NPHS1	O60500-1.1	Q896Y	Pathogenic	0.749
NPHS1	O60500-1.1	G897A	Pathogenic	0.846
NPHS1	O60500-1.1	G897C	Pathogenic	0.876
NPHS1	O60500-1.1	G897D	Pathogenic	0.928
NPHS1	O60500-1.1	G897E	Pathogenic	0.916
NPHS1	O60500-1.1	G897F	Pathogenic	0.987
NPHS1	O60500-1.1	G897H	Pathogenic	0.863
NPHS1	O60500-1.1	G897I	Pathogenic	0.975
NPHS1	O60500-1.1	G897K	Pathogenic	0.971
NPHS1	O60500-1.1	G897L	Pathogenic	0.971
NPHS1	O60500-1.1	G897M	Pathogenic	0.962
NPHS1	O60500-1.1	G897N	Pathogenic	0.944
NPHS1	O60500-1.1	G897P	Pathogenic	0.887
NPHS1	O60500-1.1	G897Q	Pathogenic	0.868
NPHS1	O60500-1.1	G897R	Pathogenic	0.979
NPHS1	O60500-1.1	G897S	Pathogenic	0.808
NPHS1	O60500-1.1	G897T	Pathogenic	0.808
NPHS1	O60500-1.1	G897V	Pathogenic	0.94
NPHS1	O60500-1.1	G897W	Pathogenic	0.998
NPHS1	O60500-1.1	G897Y	Pathogenic	0.962
NPHS1	O60500-1.1	G898A	Neutral	0.034
NPHS1	O60500-1.1	G898C	Neutral	0.043
NPHS1	O60500-1.1	G898D	Neutral	0.076
NPHS1	O60500-1.1	G898E	Neutral	0.065
NPHS1	O60500-1.1	G898F	Neutral	0.324
NPHS1	O60500-1.1	G898H	Neutral	0.039
NPHS1	O60500-1.1	G898I	Neutral	0.202
NPHS1	O60500-1.1	G898K	Neutral	0.179
NPHS1	O60500-1.1	G898L	Neutral	0.178
NPHS1	O60500-1.1	G898M	Neutral	0.139
NPHS1	O60500-1.1	G898N	Neutral	0.097
NPHS1	O60500-1.1	G898P	Neutral	0.048
NPHS1	O60500-1.1	G898Q	Neutral	0.04
NPHS1	O60500-1.1	G898R	Neutral	0.232
NPHS1	O60500-1.1	G898S	Neutral	0.026
NPHS1	O60500-1.1	G898T	Neutral	0.026
NPHS1	O60500-1.1	G898V	Neutral	0.091
NPHS1	O60500-1.1	G898W	Pathogenic	0.734
NPHS1	O60500-1.1	G898Y	Neutral	0.139
NPHS1	O60500-1.1	V899A	Pathogenic	0.528
NPHS1	O60500-1.1	V899C	Neutral	0.149
NPHS1	O60500-1.1	V899D	Neutral	0.487
NPHS1	O60500-1.1	V899E	Neutral	0.479
NPHS1	O60500-1.1	V899F	Neutral	0.273
NPHS1	O60500-1.1	V899G	Neutral	0.455
NPHS1	O60500-1.1	V899H	Neutral	0.195
NPHS1	O60500-1.1	V899I	Pathogenic	0.594
NPHS1	O60500-1.1	V899K	Pathogenic	0.742
NPHS1	O60500-1.1	V899L	Neutral	0.361
NPHS1	O60500-1.1	V899M	Neutral	0.22
NPHS1	O60500-1.1	V899N	Neutral	0.397
NPHS1	O60500-1.1	V899P	Neutral	0.137
NPHS1	O60500-1.1	V899Q	Neutral	0.357
NPHS1	O60500-1.1	V899R	Pathogenic	0.728
NPHS1	O60500-1.1	V899S	Neutral	0.422
NPHS1	O60500-1.1	V899T	Neutral	0.395
NPHS1	O60500-1.1	V899W	Neutral	0.394
NPHS1	O60500-1.1	V899Y	Neutral	0.213
NPHS1	O60500-1.1	H900A	Pathogenic	0.997
NPHS1	O60500-1.1	H900C	Pathogenic	0.997
NPHS1	O60500-1.1	H900D	Pathogenic	0.999
NPHS1	O60500-1.1	H900E	Pathogenic	0.998
NPHS1	O60500-1.1	H900F	Pathogenic	0.999
NPHS1	O60500-1.1	H900G	Pathogenic	0.998
NPHS1	O60500-1.1	H900I	Pathogenic	0.998
NPHS1	O60500-1.1	H900K	Pathogenic	0.999
NPHS1	O60500-1.1	H900L	Pathogenic	0.998
NPHS1	O60500-1.1	H900M	Pathogenic	0.998
NPHS1	O60500-1.1	H900N	Pathogenic	0.999
NPHS1	O60500-1.1	H900P	Pathogenic	0.997
NPHS1	O60500-1.1	H900Q	Pathogenic	0.997
NPHS1	O60500-1.1	H900R	Pathogenic	0.999
NPHS1	O60500-1.1	H900S	Pathogenic	0.997
NPHS1	O60500-1.1	H900T	Pathogenic	0.993
NPHS1	O60500-1.1	H900V	Pathogenic	0.997
NPHS1	O60500-1.1	H900W	Pathogenic	1.0
NPHS1	O60500-1.1	H900Y	Pathogenic	1.0
NPHS1	O60500-1.1	S901A	Pathogenic	0.627
NPHS1	O60500-1.1	S901C	Pathogenic	0.709
NPHS1	O60500-1.1	S901D	Pathogenic	0.728
NPHS1	O60500-1.1	S901E	Pathogenic	0.771
NPHS1	O60500-1.1	S901F	Pathogenic	0.945
NPHS1	O60500-1.1	S901G	Pathogenic	0.528
NPHS1	O60500-1.1	S901H	Pathogenic	0.594
NPHS1	O60500-1.1	S901I	Pathogenic	0.932
NPHS1	O60500-1.1	S901K	Pathogenic	0.913
NPHS1	O60500-1.1	S901L	Pathogenic	0.921
NPHS1	O60500-1.1	S901M	Pathogenic	0.897
NPHS1	O60500-1.1	S901N	Pathogenic	0.777
NPHS1	O60500-1.1	S901P	Pathogenic	0.644
NPHS1	O60500-1.1	S901Q	Pathogenic	0.67
NPHS1	O60500-1.1	S901R	Pathogenic	0.907
NPHS1	O60500-1.1	S901T	Pathogenic	0.685
NPHS1	O60500-1.1	S901V	Pathogenic	0.784
NPHS1	O60500-1.1	S901W	Pathogenic	0.978
NPHS1	O60500-1.1	S901Y	Pathogenic	0.853
NPHS1	O60500-1.1	S902A	Pathogenic	0.987
NPHS1	O60500-1.1	S902C	Pathogenic	0.991
NPHS1	O60500-1.1	S902D	Pathogenic	0.991
NPHS1	O60500-1.1	S902E	Pathogenic	0.993
NPHS1	O60500-1.1	S902F	Pathogenic	0.999
NPHS1	O60500-1.1	S902G	Pathogenic	0.98
NPHS1	O60500-1.1	S902H	Pathogenic	0.985
NPHS1	O60500-1.1	S902I	Pathogenic	0.998
NPHS1	O60500-1.1	S902K	Pathogenic	0.998
NPHS1	O60500-1.1	S902L	Pathogenic	0.998
NPHS1	O60500-1.1	S902M	Pathogenic	0.997
NPHS1	O60500-1.1	S902N	Pathogenic	0.993
NPHS1	O60500-1.1	S902P	Pathogenic	0.987
NPHS1	O60500-1.1	S902Q	Pathogenic	0.989
NPHS1	O60500-1.1	S902R	Pathogenic	0.998
NPHS1	O60500-1.1	S902T	Pathogenic	0.99
NPHS1	O60500-1.1	S902V	Pathogenic	0.994
NPHS1	O60500-1.1	S902W	Pathogenic	0.999
NPHS1	O60500-1.1	S902Y	Pathogenic	0.996
NPHS1	O60500-1.1	L903A	Pathogenic	0.849
NPHS1	O60500-1.1	L903C	Pathogenic	0.568
NPHS1	O60500-1.1	L903D	Pathogenic	0.827
NPHS1	O60500-1.1	L903E	Pathogenic	0.793
NPHS1	O60500-1.1	L903F	Neutral	0.289
NPHS1	O60500-1.1	L903G	Pathogenic	0.808
NPHS1	O60500-1.1	L903H	Neutral	0.496
NPHS1	O60500-1.1	L903I	Neutral	0.416
NPHS1	O60500-1.1	L903K	Pathogenic	0.898
NPHS1	O60500-1.1	L903M	Pathogenic	0.551
NPHS1	O60500-1.1	L903N	Pathogenic	0.831
NPHS1	O60500-1.1	L903P	Neutral	0.444
NPHS1	O60500-1.1	L903Q	Pathogenic	0.732
NPHS1	O60500-1.1	L903R	Pathogenic	0.924
NPHS1	O60500-1.1	L903S	Pathogenic	0.845
NPHS1	O60500-1.1	L903T	Pathogenic	0.767
NPHS1	O60500-1.1	L903V	Pathogenic	0.569
NPHS1	O60500-1.1	L903W	Neutral	0.413
NPHS1	O60500-1.1	L903Y	Neutral	0.453
NPHS1	O60500-1.1	L904A	Pathogenic	0.978
NPHS1	O60500-1.1	L904C	Pathogenic	0.913
NPHS1	O60500-1.1	L904D	Pathogenic	0.975
NPHS1	O60500-1.1	L904E	Pathogenic	0.968
NPHS1	O60500-1.1	L904F	Pathogenic	0.765
NPHS1	O60500-1.1	L904G	Pathogenic	0.971
NPHS1	O60500-1.1	L904H	Pathogenic	0.888
NPHS1	O60500-1.1	L904I	Pathogenic	0.851
NPHS1	O60500-1.1	L904K	Pathogenic	0.986
NPHS1	O60500-1.1	L904M	Pathogenic	0.908
NPHS1	O60500-1.1	L904N	Pathogenic	0.975
NPHS1	O60500-1.1	L904P	Pathogenic	0.865
NPHS1	O60500-1.1	L904Q	Pathogenic	0.956
NPHS1	O60500-1.1	L904R	Pathogenic	0.99
NPHS1	O60500-1.1	L904S	Pathogenic	0.978
NPHS1	O60500-1.1	L904T	Pathogenic	0.963
NPHS1	O60500-1.1	L904V	Pathogenic	0.913
NPHS1	O60500-1.1	L904W	Pathogenic	0.849
NPHS1	O60500-1.1	L904Y	Pathogenic	0.869
NPHS1	O60500-1.1	T905A	Pathogenic	0.783
NPHS1	O60500-1.1	T905C	Pathogenic	0.808
NPHS1	O60500-1.1	T905D	Pathogenic	0.854
NPHS1	O60500-1.1	T905E	Pathogenic	0.87
NPHS1	O60500-1.1	T905F	Pathogenic	0.955
NPHS1	O60500-1.1	T905G	Pathogenic	0.775
NPHS1	O60500-1.1	T905H	Pathogenic	0.639
NPHS1	O60500-1.1	T905I	Pathogenic	0.962
NPHS1	O60500-1.1	T905K	Pathogenic	0.954
NPHS1	O60500-1.1	T905L	Pathogenic	0.956
NPHS1	O60500-1.1	T905M	Pathogenic	0.915
NPHS1	O60500-1.1	T905N	Pathogenic	0.874
NPHS1	O60500-1.1	T905P	Pathogenic	0.721
NPHS1	O60500-1.1	T905Q	Pathogenic	0.802
NPHS1	O60500-1.1	T905R	Pathogenic	0.967
NPHS1	O60500-1.1	T905S	Pathogenic	0.87
NPHS1	O60500-1.1	T905V	Pathogenic	0.909
NPHS1	O60500-1.1	T905W	Pathogenic	0.988
NPHS1	O60500-1.1	T905Y	Pathogenic	0.878
NPHS1	O60500-1.1	I906A	Pathogenic	0.998
NPHS1	O60500-1.1	I906C	Pathogenic	0.991
NPHS1	O60500-1.1	I906D	Pathogenic	0.998
NPHS1	O60500-1.1	I906E	Pathogenic	0.997
NPHS1	O60500-1.1	I906F	Pathogenic	0.963
NPHS1	O60500-1.1	I906G	Pathogenic	0.997
NPHS1	O60500-1.1	I906H	Pathogenic	0.988
NPHS1	O60500-1.1	I906K	Pathogenic	0.998
NPHS1	O60500-1.1	I906L	Pathogenic	0.981
NPHS1	O60500-1.1	I906M	Pathogenic	0.986
NPHS1	O60500-1.1	I906N	Pathogenic	0.998
NPHS1	O60500-1.1	I906P	Pathogenic	0.985
NPHS1	O60500-1.1	I906Q	Pathogenic	0.994
NPHS1	O60500-1.1	I906R	Pathogenic	0.999
NPHS1	O60500-1.1	I906S	Pathogenic	0.998
NPHS1	O60500-1.1	I906T	Pathogenic	0.996
NPHS1	O60500-1.1	I906V	Pathogenic	0.996
NPHS1	O60500-1.1	I906W	Pathogenic	0.967
NPHS1	O60500-1.1	I906Y	Pathogenic	0.986
NPHS1	O60500-1.1	A907C	Pathogenic	0.855
NPHS1	O60500-1.1	A907D	Pathogenic	0.845
NPHS1	O60500-1.1	A907E	Pathogenic	0.911
NPHS1	O60500-1.1	A907F	Pathogenic	0.966
NPHS1	O60500-1.1	A907G	Pathogenic	0.774
NPHS1	O60500-1.1	A907H	Pathogenic	0.729
NPHS1	O60500-1.1	A907I	Pathogenic	0.971
NPHS1	O60500-1.1	A907K	Pathogenic	0.97
NPHS1	O60500-1.1	A907L	Pathogenic	0.966
NPHS1	O60500-1.1	A907M	Pathogenic	0.934
NPHS1	O60500-1.1	A907N	Pathogenic	0.827
NPHS1	O60500-1.1	A907P	Pathogenic	0.746
NPHS1	O60500-1.1	A907Q	Pathogenic	0.861
NPHS1	O60500-1.1	A907R	Pathogenic	0.978
NPHS1	O60500-1.1	A907S	Pathogenic	0.799
NPHS1	O60500-1.1	A907T	Pathogenic	0.734
NPHS1	O60500-1.1	A907V	Pathogenic	0.929
NPHS1	O60500-1.1	A907W	Pathogenic	0.986
NPHS1	O60500-1.1	A907Y	Pathogenic	0.904
NPHS1	O60500-1.1	N908A	Pathogenic	0.938
NPHS1	O60500-1.1	N908C	Pathogenic	0.946
NPHS1	O60500-1.1	N908D	Pathogenic	0.904
NPHS1	O60500-1.1	N908E	Pathogenic	0.863
NPHS1	O60500-1.1	N908F	Pathogenic	0.991
NPHS1	O60500-1.1	N908G	Pathogenic	0.971
NPHS1	O60500-1.1	N908H	Pathogenic	0.97
NPHS1	O60500-1.1	N908I	Pathogenic	0.989
NPHS1	O60500-1.1	N908K	Pathogenic	0.951
NPHS1	O60500-1.1	N908L	Pathogenic	0.987
NPHS1	O60500-1.1	N908M	Pathogenic	0.983
NPHS1	O60500-1.1	N908P	Pathogenic	0.942
NPHS1	O60500-1.1	N908Q	Pathogenic	0.922
NPHS1	O60500-1.1	N908R	Pathogenic	0.965
NPHS1	O60500-1.1	N908S	Pathogenic	0.963
NPHS1	O60500-1.1	N908T	Pathogenic	0.944
NPHS1	O60500-1.1	N908V	Pathogenic	0.961
NPHS1	O60500-1.1	N908W	Pathogenic	0.997
NPHS1	O60500-1.1	N908Y	Pathogenic	0.983
NPHS1	O60500-1.1	V909A	Pathogenic	0.995
NPHS1	O60500-1.1	V909C	Pathogenic	0.971
NPHS1	O60500-1.1	V909D	Pathogenic	0.995
NPHS1	O60500-1.1	V909E	Pathogenic	0.994
NPHS1	O60500-1.1	V909F	Pathogenic	0.986
NPHS1	O60500-1.1	V909G	Pathogenic	0.994
NPHS1	O60500-1.1	V909H	Pathogenic	0.979
NPHS1	O60500-1.1	V909I	Pathogenic	0.996
NPHS1	O60500-1.1	V909K	Pathogenic	0.998
NPHS1	O60500-1.1	V909L	Pathogenic	0.991
NPHS1	O60500-1.1	V909M	Pathogenic	0.982
NPHS1	O60500-1.1	V909N	Pathogenic	0.992
NPHS1	O60500-1.1	V909P	Pathogenic	0.968
NPHS1	O60500-1.1	V909Q	Pathogenic	0.991
NPHS1	O60500-1.1	V909R	Pathogenic	0.998
NPHS1	O60500-1.1	V909S	Pathogenic	0.993
NPHS1	O60500-1.1	V909T	Pathogenic	0.992
NPHS1	O60500-1.1	V909W	Pathogenic	0.992
NPHS1	O60500-1.1	V909Y	Pathogenic	0.981
NPHS1	O60500-1.1	S910A	Pathogenic	0.979
NPHS1	O60500-1.1	S910C	Pathogenic	0.985
NPHS1	O60500-1.1	S910D	Pathogenic	0.986
NPHS1	O60500-1.1	S910E	Pathogenic	0.989
NPHS1	O60500-1.1	S910F	Pathogenic	0.998
NPHS1	O60500-1.1	S910G	Pathogenic	0.968
NPHS1	O60500-1.1	S910H	Pathogenic	0.976
NPHS1	O60500-1.1	S910I	Pathogenic	0.997
NPHS1	O60500-1.1	S910K	Pathogenic	0.997
NPHS1	O60500-1.1	S910L	Pathogenic	0.997
NPHS1	O60500-1.1	S910M	Pathogenic	0.996
NPHS1	O60500-1.1	S910N	Pathogenic	0.99
NPHS1	O60500-1.1	S910P	Pathogenic	0.98
NPHS1	O60500-1.1	S910Q	Pathogenic	0.982
NPHS1	O60500-1.1	S910R	Pathogenic	0.996
NPHS1	O60500-1.1	S910T	Pathogenic	0.983
NPHS1	O60500-1.1	S910V	Pathogenic	0.99
NPHS1	O60500-1.1	S910W	Pathogenic	0.999
NPHS1	O60500-1.1	S910Y	Pathogenic	0.994
NPHS1	O60500-1.1	A911C	Pathogenic	0.982
NPHS1	O60500-1.1	A911D	Pathogenic	0.981
NPHS1	O60500-1.1	A911E	Pathogenic	0.99
NPHS1	O60500-1.1	A911F	Pathogenic	0.996
NPHS1	O60500-1.1	A911G	Pathogenic	0.969
NPHS1	O60500-1.1	A911H	Pathogenic	0.961
NPHS1	O60500-1.1	A911I	Pathogenic	0.997
NPHS1	O60500-1.1	A911K	Pathogenic	0.997
NPHS1	O60500-1.1	A911L	Pathogenic	0.996
NPHS1	O60500-1.1	A911M	Pathogenic	0.992
NPHS1	O60500-1.1	A911N	Pathogenic	0.978
NPHS1	O60500-1.1	A911P	Pathogenic	0.965
NPHS1	O60500-1.1	A911Q	Pathogenic	0.983
NPHS1	O60500-1.1	A911R	Pathogenic	0.998
NPHS1	O60500-1.1	A911S	Pathogenic	0.973
NPHS1	O60500-1.1	A911T	Pathogenic	0.962
NPHS1	O60500-1.1	A911V	Pathogenic	0.992
NPHS1	O60500-1.1	A911W	Pathogenic	0.999
NPHS1	O60500-1.1	A911Y	Pathogenic	0.989
NPHS1	O60500-1.1	A912C	Pathogenic	0.764
NPHS1	O60500-1.1	A912D	Pathogenic	0.749
NPHS1	O60500-1.1	A912E	Pathogenic	0.848
NPHS1	O60500-1.1	A912F	Pathogenic	0.939
NPHS1	O60500-1.1	A912G	Pathogenic	0.652
NPHS1	O60500-1.1	A912H	Pathogenic	0.596
NPHS1	O60500-1.1	A912I	Pathogenic	0.948
NPHS1	O60500-1.1	A912K	Pathogenic	0.946
NPHS1	O60500-1.1	A912L	Pathogenic	0.939
NPHS1	O60500-1.1	A912M	Pathogenic	0.885
NPHS1	O60500-1.1	A912N	Pathogenic	0.723
NPHS1	O60500-1.1	A912P	Pathogenic	0.617
NPHS1	O60500-1.1	A912Q	Pathogenic	0.772
NPHS1	O60500-1.1	A912R	Pathogenic	0.96
NPHS1	O60500-1.1	A912S	Pathogenic	0.685
NPHS1	O60500-1.1	A912T	Pathogenic	0.602
NPHS1	O60500-1.1	A912V	Pathogenic	0.878
NPHS1	O60500-1.1	A912W	Pathogenic	0.975
NPHS1	O60500-1.1	A912Y	Pathogenic	0.838
NPHS1	O60500-1.1	Q913A	Pathogenic	0.61
NPHS1	O60500-1.1	Q913C	Pathogenic	0.551
NPHS1	O60500-1.1	Q913D	Pathogenic	0.578
NPHS1	O60500-1.1	Q913E	Pathogenic	0.62
NPHS1	O60500-1.1	Q913F	Pathogenic	0.775
NPHS1	O60500-1.1	Q913G	Pathogenic	0.51
NPHS1	O60500-1.1	Q913H	Neutral	0.394
NPHS1	O60500-1.1	Q913I	Pathogenic	0.731
NPHS1	O60500-1.1	Q913K	Pathogenic	0.73
NPHS1	O60500-1.1	Q913L	Pathogenic	0.777
NPHS1	O60500-1.1	Q913M	Pathogenic	0.794
NPHS1	O60500-1.1	Q913N	Neutral	0.486
NPHS1	O60500-1.1	Q913P	Pathogenic	0.626
NPHS1	O60500-1.1	Q913R	Pathogenic	0.79
NPHS1	O60500-1.1	Q913S	Pathogenic	0.548
NPHS1	O60500-1.1	Q913T	Neutral	0.44
NPHS1	O60500-1.1	Q913V	Pathogenic	0.623
NPHS1	O60500-1.1	Q913W	Pathogenic	0.952
NPHS1	O60500-1.1	Q913Y	Pathogenic	0.72
NPHS1	O60500-1.1	D914A	Pathogenic	0.997
NPHS1	O60500-1.1	D914C	Pathogenic	0.997
NPHS1	O60500-1.1	D914E	Pathogenic	0.997
NPHS1	O60500-1.1	D914F	Pathogenic	1.0
NPHS1	O60500-1.1	D914G	Pathogenic	0.998
NPHS1	O60500-1.1	D914H	Pathogenic	0.997
NPHS1	O60500-1.1	D914I	Pathogenic	1.0
NPHS1	O60500-1.1	D914K	Pathogenic	0.995
NPHS1	O60500-1.1	D914L	Pathogenic	0.999
NPHS1	O60500-1.1	D914M	Pathogenic	0.999
NPHS1	O60500-1.1	D914N	Pathogenic	0.994
NPHS1	O60500-1.1	D914P	Pathogenic	0.998
NPHS1	O60500-1.1	D914Q	Pathogenic	0.997
NPHS1	O60500-1.1	D914R	Pathogenic	0.995
NPHS1	O60500-1.1	D914S	Pathogenic	0.997
NPHS1	O60500-1.1	D914T	Pathogenic	0.996
NPHS1	O60500-1.1	D914V	Pathogenic	0.998
NPHS1	O60500-1.1	D914W	Pathogenic	1.0
NPHS1	O60500-1.1	D914Y	Pathogenic	0.999
NPHS1	O60500-1.1	Y915A	Pathogenic	0.999
NPHS1	O60500-1.1	Y915C	Pathogenic	0.998
NPHS1	O60500-1.1	Y915D	Pathogenic	1.0
NPHS1	O60500-1.1	Y915E	Pathogenic	1.0
NPHS1	O60500-1.1	Y915F	Pathogenic	1.0
NPHS1	O60500-1.1	Y915G	Pathogenic	1.0
NPHS1	O60500-1.1	Y915H	Pathogenic	1.0
NPHS1	O60500-1.1	Y915I	Pathogenic	0.999
NPHS1	O60500-1.1	Y915K	Pathogenic	1.0
NPHS1	O60500-1.1	Y915L	Pathogenic	0.999
NPHS1	O60500-1.1	Y915M	Pathogenic	0.998
NPHS1	O60500-1.1	Y915N	Pathogenic	1.0
NPHS1	O60500-1.1	Y915P	Pathogenic	0.998
NPHS1	O60500-1.1	Y915Q	Pathogenic	1.0
NPHS1	O60500-1.1	Y915R	Pathogenic	1.0
NPHS1	O60500-1.1	Y915S	Pathogenic	1.0
NPHS1	O60500-1.1	Y915T	Pathogenic	0.999
NPHS1	O60500-1.1	Y915V	Pathogenic	0.999
NPHS1	O60500-1.1	Y915W	Pathogenic	1.0
NPHS1	O60500-1.1	A916C	Pathogenic	0.989
NPHS1	O60500-1.1	A916D	Pathogenic	0.988
NPHS1	O60500-1.1	A916E	Pathogenic	0.994
NPHS1	O60500-1.1	A916F	Pathogenic	0.998
NPHS1	O60500-1.1	A916G	Pathogenic	0.982
NPHS1	O60500-1.1	A916H	Pathogenic	0.977
NPHS1	O60500-1.1	A916I	Pathogenic	0.998
NPHS1	O60500-1.1	A916K	Pathogenic	0.998
NPHS1	O60500-1.1	A916L	Pathogenic	0.998
NPHS1	O60500-1.1	A916M	Pathogenic	0.995
NPHS1	O60500-1.1	A916N	Pathogenic	0.987
NPHS1	O60500-1.1	A916P	Pathogenic	0.979
NPHS1	O60500-1.1	A916Q	Pathogenic	0.99
NPHS1	O60500-1.1	A916R	Pathogenic	0.999
NPHS1	O60500-1.1	A916S	Pathogenic	0.984
NPHS1	O60500-1.1	A916T	Pathogenic	0.977
NPHS1	O60500-1.1	A916V	Pathogenic	0.995
NPHS1	O60500-1.1	A916W	Pathogenic	0.999
NPHS1	O60500-1.1	A916Y	Pathogenic	0.993
NPHS1	O60500-1.1	L917A	Pathogenic	0.637
NPHS1	O60500-1.1	L917C	Neutral	0.291
NPHS1	O60500-1.1	L917D	Pathogenic	0.598
NPHS1	O60500-1.1	L917E	Pathogenic	0.544
NPHS1	O60500-1.1	L917F	Neutral	0.112
NPHS1	O60500-1.1	L917G	Pathogenic	0.567
NPHS1	O60500-1.1	L917H	Neutral	0.235
NPHS1	O60500-1.1	L917I	Neutral	0.181
NPHS1	O60500-1.1	L917K	Pathogenic	0.732
NPHS1	O60500-1.1	L917M	Neutral	0.277
NPHS1	O60500-1.1	L917N	Pathogenic	0.606
NPHS1	O60500-1.1	L917P	Neutral	0.199
NPHS1	O60500-1.1	L917Q	Neutral	0.459
NPHS1	O60500-1.1	L917R	Pathogenic	0.792
NPHS1	O60500-1.1	L917S	Pathogenic	0.63
NPHS1	O60500-1.1	L917T	Pathogenic	0.506
NPHS1	O60500-1.1	L917V	Neutral	0.291
NPHS1	O60500-1.1	L917W	Neutral	0.18
NPHS1	O60500-1.1	L917Y	Neutral	0.205
NPHS1	O60500-1.1	F918A	Pathogenic	1.0
NPHS1	O60500-1.1	F918C	Pathogenic	0.999
NPHS1	O60500-1.1	F918D	Pathogenic	1.0
NPHS1	O60500-1.1	F918E	Pathogenic	1.0
NPHS1	O60500-1.1	F918G	Pathogenic	1.0
NPHS1	O60500-1.1	F918H	Pathogenic	1.0
NPHS1	O60500-1.1	F918I	Pathogenic	0.996
NPHS1	O60500-1.1	F918K	Pathogenic	1.0
NPHS1	O60500-1.1	F918L	Pathogenic	0.997
NPHS1	O60500-1.1	F918M	Pathogenic	0.998
NPHS1	O60500-1.1	F918N	Pathogenic	1.0
NPHS1	O60500-1.1	F918P	Pathogenic	0.998
NPHS1	O60500-1.1	F918Q	Pathogenic	0.999
NPHS1	O60500-1.1	F918R	Pathogenic	1.0
NPHS1	O60500-1.1	F918S	Pathogenic	1.0
NPHS1	O60500-1.1	F918T	Pathogenic	1.0
NPHS1	O60500-1.1	F918V	Pathogenic	0.998
NPHS1	O60500-1.1	F918W	Pathogenic	0.999
NPHS1	O60500-1.1	F918Y	Pathogenic	1.0
NPHS1	O60500-1.1	T919A	Pathogenic	0.919
NPHS1	O60500-1.1	T919C	Pathogenic	0.93
NPHS1	O60500-1.1	T919D	Pathogenic	0.949
NPHS1	O60500-1.1	T919E	Pathogenic	0.955
NPHS1	O60500-1.1	T919F	Pathogenic	0.985
NPHS1	O60500-1.1	T919G	Pathogenic	0.916
NPHS1	O60500-1.1	T919H	Pathogenic	0.848
NPHS1	O60500-1.1	T919I	Pathogenic	0.988
NPHS1	O60500-1.1	T919K	Pathogenic	0.985
NPHS1	O60500-1.1	T919L	Pathogenic	0.986
NPHS1	O60500-1.1	T919M	Pathogenic	0.971
NPHS1	O60500-1.1	T919N	Pathogenic	0.956
NPHS1	O60500-1.1	T919P	Pathogenic	0.891
NPHS1	O60500-1.1	T919Q	Pathogenic	0.927
NPHS1	O60500-1.1	T919R	Pathogenic	0.989
NPHS1	O60500-1.1	T919S	Pathogenic	0.955
NPHS1	O60500-1.1	T919V	Pathogenic	0.969
NPHS1	O60500-1.1	T919W	Pathogenic	0.996
NPHS1	O60500-1.1	T919Y	Pathogenic	0.958
NPHS1	O60500-1.1	C920A	Pathogenic	0.975
NPHS1	O60500-1.1	C920D	Pathogenic	0.977
NPHS1	O60500-1.1	C920E	Pathogenic	0.973
NPHS1	O60500-1.1	C920F	Pathogenic	0.978
NPHS1	O60500-1.1	C920G	Pathogenic	0.967
NPHS1	O60500-1.1	C920H	Pathogenic	0.954
NPHS1	O60500-1.1	C920I	Pathogenic	0.981
NPHS1	O60500-1.1	C920K	Pathogenic	0.994
NPHS1	O60500-1.1	C920L	Pathogenic	0.978
NPHS1	O60500-1.1	C920M	Pathogenic	0.956
NPHS1	O60500-1.1	C920N	Pathogenic	0.974
NPHS1	O60500-1.1	C920P	Pathogenic	0.818
NPHS1	O60500-1.1	C920Q	Pathogenic	0.97
NPHS1	O60500-1.1	C920R	Pathogenic	0.996
NPHS1	O60500-1.1	C920S	Pathogenic	0.974
NPHS1	O60500-1.1	C920T	Pathogenic	0.955
NPHS1	O60500-1.1	C920V	Pathogenic	0.932
NPHS1	O60500-1.1	C920W	Pathogenic	0.994
NPHS1	O60500-1.1	C920Y	Pathogenic	0.94
NPHS1	O60500-1.1	T921A	Pathogenic	0.641
NPHS1	O60500-1.1	T921C	Pathogenic	0.676
NPHS1	O60500-1.1	T921D	Pathogenic	0.743
NPHS1	O60500-1.1	T921E	Pathogenic	0.768
NPHS1	O60500-1.1	T921F	Pathogenic	0.914
NPHS1	O60500-1.1	T921G	Pathogenic	0.63
NPHS1	O60500-1.1	T921H	Neutral	0.466
NPHS1	O60500-1.1	T921I	Pathogenic	0.926
NPHS1	O60500-1.1	T921K	Pathogenic	0.912
NPHS1	O60500-1.1	T921L	Pathogenic	0.915
NPHS1	O60500-1.1	T921M	Pathogenic	0.842
NPHS1	O60500-1.1	T921N	Pathogenic	0.775
NPHS1	O60500-1.1	T921P	Pathogenic	0.561
NPHS1	O60500-1.1	T921Q	Pathogenic	0.667
NPHS1	O60500-1.1	T921R	Pathogenic	0.935
NPHS1	O60500-1.1	T921S	Pathogenic	0.768
NPHS1	O60500-1.1	T921V	Pathogenic	0.832
NPHS1	O60500-1.1	T921W	Pathogenic	0.976
NPHS1	O60500-1.1	T921Y	Pathogenic	0.781
NPHS1	O60500-1.1	A922C	Pathogenic	0.99
NPHS1	O60500-1.1	A922D	Pathogenic	0.989
NPHS1	O60500-1.1	A922E	Pathogenic	0.994
NPHS1	O60500-1.1	A922F	Pathogenic	0.998
NPHS1	O60500-1.1	A922G	Pathogenic	0.982
NPHS1	O60500-1.1	A922H	Pathogenic	0.977
NPHS1	O60500-1.1	A922I	Pathogenic	0.998
NPHS1	O60500-1.1	A922K	Pathogenic	0.998
NPHS1	O60500-1.1	A922L	Pathogenic	0.998
NPHS1	O60500-1.1	A922M	Pathogenic	0.996
NPHS1	O60500-1.1	A922N	Pathogenic	0.987
NPHS1	O60500-1.1	A922P	Pathogenic	0.979
NPHS1	O60500-1.1	A922Q	Pathogenic	0.99
NPHS1	O60500-1.1	A922R	Pathogenic	0.999
NPHS1	O60500-1.1	A922S	Pathogenic	0.985
NPHS1	O60500-1.1	A922T	Pathogenic	0.978
NPHS1	O60500-1.1	A922V	Pathogenic	0.995
NPHS1	O60500-1.1	A922W	Pathogenic	0.999
NPHS1	O60500-1.1	A922Y	Pathogenic	0.993
NPHS1	O60500-1.1	T923A	Neutral	0.318
NPHS1	O60500-1.1	T923C	Neutral	0.352
NPHS1	O60500-1.1	T923D	Neutral	0.43
NPHS1	O60500-1.1	T923E	Neutral	0.464
NPHS1	O60500-1.1	T923F	Pathogenic	0.735
NPHS1	O60500-1.1	T923G	Neutral	0.308
NPHS1	O60500-1.1	T923H	Neutral	0.186
NPHS1	O60500-1.1	T923I	Pathogenic	0.765
NPHS1	O60500-1.1	T923K	Pathogenic	0.729
NPHS1	O60500-1.1	T923L	Pathogenic	0.736
NPHS1	O60500-1.1	T923M	Pathogenic	0.581
NPHS1	O60500-1.1	T923N	Neutral	0.473
NPHS1	O60500-1.1	T923P	Neutral	0.25
NPHS1	O60500-1.1	T923Q	Neutral	0.343
NPHS1	O60500-1.1	T923R	Pathogenic	0.789
NPHS1	O60500-1.1	T923S	Neutral	0.463
NPHS1	O60500-1.1	T923V	Pathogenic	0.564
NPHS1	O60500-1.1	T923W	Pathogenic	0.914
NPHS1	O60500-1.1	T923Y	Neutral	0.482
NPHS1	O60500-1.1	N924A	Pathogenic	0.998
NPHS1	O60500-1.1	N924C	Pathogenic	0.998
NPHS1	O60500-1.1	N924D	Pathogenic	0.997
NPHS1	O60500-1.1	N924E	Pathogenic	0.995
NPHS1	O60500-1.1	N924F	Pathogenic	1.0
NPHS1	O60500-1.1	N924G	Pathogenic	0.999
NPHS1	O60500-1.1	N924H	Pathogenic	0.999
NPHS1	O60500-1.1	N924I	Pathogenic	1.0
NPHS1	O60500-1.1	N924K	Pathogenic	0.998
NPHS1	O60500-1.1	N924L	Pathogenic	1.0
NPHS1	O60500-1.1	N924M	Pathogenic	0.999
NPHS1	O60500-1.1	N924P	Pathogenic	0.998
NPHS1	O60500-1.1	N924Q	Pathogenic	0.997
NPHS1	O60500-1.1	N924R	Pathogenic	0.999
NPHS1	O60500-1.1	N924S	Pathogenic	0.999
NPHS1	O60500-1.1	N924T	Pathogenic	0.998
NPHS1	O60500-1.1	N924V	Pathogenic	0.999
NPHS1	O60500-1.1	N924W	Pathogenic	1.0
NPHS1	O60500-1.1	N924Y	Pathogenic	0.999
NPHS1	O60500-1.1	A925C	Neutral	0.01
NPHS1	O60500-1.1	A925D	Neutral	0.01
NPHS1	O60500-1.1	A925E	Neutral	0.018
NPHS1	O60500-1.1	A925F	Neutral	0.048
NPHS1	O60500-1.1	A925G	Neutral	0.006
NPHS1	O60500-1.1	A925H	Neutral	0.005
NPHS1	O60500-1.1	A925I	Neutral	0.056
NPHS1	O60500-1.1	A925K	Neutral	0.054
NPHS1	O60500-1.1	A925L	Neutral	0.048
NPHS1	O60500-1.1	A925M	Neutral	0.025
NPHS1	O60500-1.1	A925N	Neutral	0.008
NPHS1	O60500-1.1	A925P	Neutral	0.005
NPHS1	O60500-1.1	A925Q	Neutral	0.011
NPHS1	O60500-1.1	A925R	Neutral	0.073
NPHS1	O60500-1.1	A925S	Neutral	0.007
NPHS1	O60500-1.1	A925T	Neutral	0.005
NPHS1	O60500-1.1	A925V	Neutral	0.023
NPHS1	O60500-1.1	A925W	Neutral	0.115
NPHS1	O60500-1.1	A925Y	Neutral	0.017
NPHS1	O60500-1.1	L926A	Pathogenic	0.997
NPHS1	O60500-1.1	L926C	Pathogenic	0.986
NPHS1	O60500-1.1	L926D	Pathogenic	0.996
NPHS1	O60500-1.1	L926E	Pathogenic	0.995
NPHS1	O60500-1.1	L926F	Pathogenic	0.956
NPHS1	O60500-1.1	L926G	Pathogenic	0.996
NPHS1	O60500-1.1	L926H	Pathogenic	0.981
NPHS1	O60500-1.1	L926I	Pathogenic	0.975
NPHS1	O60500-1.1	L926K	Pathogenic	0.998
NPHS1	O60500-1.1	L926M	Pathogenic	0.985
NPHS1	O60500-1.1	L926N	Pathogenic	0.996
NPHS1	O60500-1.1	L926P	Pathogenic	0.977
NPHS1	O60500-1.1	L926Q	Pathogenic	0.993
NPHS1	O60500-1.1	L926R	Pathogenic	0.998
NPHS1	O60500-1.1	L926S	Pathogenic	0.997
NPHS1	O60500-1.1	L926T	Pathogenic	0.994
NPHS1	O60500-1.1	L926V	Pathogenic	0.986
NPHS1	O60500-1.1	L926W	Pathogenic	0.974
NPHS1	O60500-1.1	L926Y	Pathogenic	0.978
NPHS1	O60500-1.1	G927A	Pathogenic	0.985
NPHS1	O60500-1.1	G927C	Pathogenic	0.988
NPHS1	O60500-1.1	G927D	Pathogenic	0.993
NPHS1	O60500-1.1	G927E	Pathogenic	0.992
NPHS1	O60500-1.1	G927F	Pathogenic	0.999
NPHS1	O60500-1.1	G927H	Pathogenic	0.987
NPHS1	O60500-1.1	G927I	Pathogenic	0.998
NPHS1	O60500-1.1	G927K	Pathogenic	0.997
NPHS1	O60500-1.1	G927L	Pathogenic	0.997
NPHS1	O60500-1.1	G927M	Pathogenic	0.997
NPHS1	O60500-1.1	G927N	Pathogenic	0.995
NPHS1	O60500-1.1	G927P	Pathogenic	0.989
NPHS1	O60500-1.1	G927Q	Pathogenic	0.987
NPHS1	O60500-1.1	G927R	Pathogenic	0.998
NPHS1	O60500-1.1	G927S	Pathogenic	0.98
NPHS1	O60500-1.1	G927T	Pathogenic	0.98
NPHS1	O60500-1.1	G927V	Pathogenic	0.995
NPHS1	O60500-1.1	G927W	Pathogenic	1.0
NPHS1	O60500-1.1	G927Y	Pathogenic	0.997
NPHS1	O60500-1.1	S928A	Neutral	0.163
NPHS1	O60500-1.1	S928C	Neutral	0.22
NPHS1	O60500-1.1	S928D	Neutral	0.236
NPHS1	O60500-1.1	S928E	Neutral	0.28
NPHS1	O60500-1.1	S928F	Pathogenic	0.666
NPHS1	O60500-1.1	S928G	Neutral	0.114
NPHS1	O60500-1.1	S928H	Neutral	0.145
NPHS1	O60500-1.1	S928I	Pathogenic	0.611
NPHS1	O60500-1.1	S928K	Pathogenic	0.548
NPHS1	O60500-1.1	S928L	Pathogenic	0.574
NPHS1	O60500-1.1	S928M	Pathogenic	0.5
NPHS1	O60500-1.1	S928N	Neutral	0.287
NPHS1	O60500-1.1	S928P	Neutral	0.173
NPHS1	O60500-1.1	S928Q	Neutral	0.19
NPHS1	O60500-1.1	S928R	Pathogenic	0.53
NPHS1	O60500-1.1	S928T	Neutral	0.2
NPHS1	O60500-1.1	S928V	Neutral	0.295
NPHS1	O60500-1.1	S928W	Pathogenic	0.837
NPHS1	O60500-1.1	S928Y	Neutral	0.401
NPHS1	O60500-1.1	D929A	Pathogenic	0.994
NPHS1	O60500-1.1	D929C	Pathogenic	0.995
NPHS1	O60500-1.1	D929E	Pathogenic	0.995
NPHS1	O60500-1.1	D929F	Pathogenic	0.999
NPHS1	O60500-1.1	D929G	Pathogenic	0.996
NPHS1	O60500-1.1	D929H	Pathogenic	0.995
NPHS1	O60500-1.1	D929I	Pathogenic	0.999
NPHS1	O60500-1.1	D929K	Pathogenic	0.991
NPHS1	O60500-1.1	D929L	Pathogenic	0.999
NPHS1	O60500-1.1	D929M	Pathogenic	0.998
NPHS1	O60500-1.1	D929N	Pathogenic	0.99
NPHS1	O60500-1.1	D929P	Pathogenic	0.996
NPHS1	O60500-1.1	D929Q	Pathogenic	0.994
NPHS1	O60500-1.1	D929R	Pathogenic	0.991
NPHS1	O60500-1.1	D929S	Pathogenic	0.995
NPHS1	O60500-1.1	D929T	Pathogenic	0.993
NPHS1	O60500-1.1	D929V	Pathogenic	0.997
NPHS1	O60500-1.1	D929W	Pathogenic	1.0
NPHS1	O60500-1.1	D929Y	Pathogenic	0.998
NPHS1	O60500-1.1	Q930A	Neutral	0.012
NPHS1	O60500-1.1	Q930C	Neutral	0.009
NPHS1	O60500-1.1	Q930D	Neutral	0.011
NPHS1	O60500-1.1	Q930E	Neutral	0.013
NPHS1	O60500-1.1	Q930F	Neutral	0.026
NPHS1	O60500-1.1	Q930G	Neutral	0.008
NPHS1	O60500-1.1	Q930H	Neutral	0.005
NPHS1	O60500-1.1	Q930I	Neutral	0.021
NPHS1	O60500-1.1	Q930K	Neutral	0.021
NPHS1	O60500-1.1	Q930L	Neutral	0.026
NPHS1	O60500-1.1	Q930M	Neutral	0.029
NPHS1	O60500-1.1	Q930N	Neutral	0.007
NPHS1	O60500-1.1	Q930P	Neutral	0.013
NPHS1	O60500-1.1	Q930R	Neutral	0.028
NPHS1	O60500-1.1	Q930S	Neutral	0.009
NPHS1	O60500-1.1	Q930T	Neutral	0.006
NPHS1	O60500-1.1	Q930V	Neutral	0.013
NPHS1	O60500-1.1	Q930W	Neutral	0.134
NPHS1	O60500-1.1	Q930Y	Neutral	0.02
NPHS1	O60500-1.1	T931A	Neutral	0.185
NPHS1	O60500-1.1	T931C	Neutral	0.209
NPHS1	O60500-1.1	T931D	Neutral	0.269
NPHS1	O60500-1.1	T931E	Neutral	0.296
NPHS1	O60500-1.1	T931F	Pathogenic	0.574
NPHS1	O60500-1.1	T931G	Neutral	0.178
NPHS1	O60500-1.1	T931H	Neutral	0.1
NPHS1	O60500-1.1	T931I	Pathogenic	0.613
NPHS1	O60500-1.1	T931K	Pathogenic	0.567
NPHS1	O60500-1.1	T931L	Pathogenic	0.576
NPHS1	O60500-1.1	T931M	Neutral	0.403
NPHS1	O60500-1.1	T931N	Neutral	0.304
NPHS1	O60500-1.1	T931P	Neutral	0.14
NPHS1	O60500-1.1	T931Q	Neutral	0.203
NPHS1	O60500-1.1	T931R	Pathogenic	0.646
NPHS1	O60500-1.1	T931S	Neutral	0.296
NPHS1	O60500-1.1	T931V	Neutral	0.386
NPHS1	O60500-1.1	T931W	Pathogenic	0.838
NPHS1	O60500-1.1	T931Y	Neutral	0.311
NPHS1	O60500-1.1	N932A	Pathogenic	0.86
NPHS1	O60500-1.1	N932C	Pathogenic	0.878
NPHS1	O60500-1.1	N932D	Pathogenic	0.794
NPHS1	O60500-1.1	N932E	Pathogenic	0.719
NPHS1	O60500-1.1	N932F	Pathogenic	0.979
NPHS1	O60500-1.1	N932G	Pathogenic	0.931
NPHS1	O60500-1.1	N932H	Pathogenic	0.93
NPHS1	O60500-1.1	N932I	Pathogenic	0.974
NPHS1	O60500-1.1	N932K	Pathogenic	0.889
NPHS1	O60500-1.1	N932L	Pathogenic	0.97
NPHS1	O60500-1.1	N932M	Pathogenic	0.96
NPHS1	O60500-1.1	N932P	Pathogenic	0.868
NPHS1	O60500-1.1	N932Q	Pathogenic	0.828
NPHS1	O60500-1.1	N932R	Pathogenic	0.917
NPHS1	O60500-1.1	N932S	Pathogenic	0.914
NPHS1	O60500-1.1	N932T	Pathogenic	0.873
NPHS1	O60500-1.1	N932V	Pathogenic	0.909
NPHS1	O60500-1.1	N932W	Pathogenic	0.992
NPHS1	O60500-1.1	N932Y	Pathogenic	0.96
NPHS1	O60500-1.1	I933A	Pathogenic	0.999
NPHS1	O60500-1.1	I933C	Pathogenic	0.998
NPHS1	O60500-1.1	I933D	Pathogenic	1.0
NPHS1	O60500-1.1	I933E	Pathogenic	0.999
NPHS1	O60500-1.1	I933F	Pathogenic	0.99
NPHS1	O60500-1.1	I933G	Pathogenic	0.999
NPHS1	O60500-1.1	I933H	Pathogenic	0.997
NPHS1	O60500-1.1	I933K	Pathogenic	0.999
NPHS1	O60500-1.1	I933L	Pathogenic	0.995
NPHS1	O60500-1.1	I933M	Pathogenic	0.996
NPHS1	O60500-1.1	I933N	Pathogenic	0.999
NPHS1	O60500-1.1	I933P	Pathogenic	0.996
NPHS1	O60500-1.1	I933Q	Pathogenic	0.998
NPHS1	O60500-1.1	I933R	Pathogenic	1.0
NPHS1	O60500-1.1	I933S	Pathogenic	0.999
NPHS1	O60500-1.1	I933T	Pathogenic	0.999
NPHS1	O60500-1.1	I933V	Pathogenic	0.999
NPHS1	O60500-1.1	I933W	Pathogenic	0.991
NPHS1	O60500-1.1	I933Y	Pathogenic	0.996
NPHS1	O60500-1.1	Q934A	Pathogenic	0.997
NPHS1	O60500-1.1	Q934C	Pathogenic	0.997
NPHS1	O60500-1.1	Q934D	Pathogenic	0.997
NPHS1	O60500-1.1	Q934E	Pathogenic	0.998
NPHS1	O60500-1.1	Q934F	Pathogenic	0.999
NPHS1	O60500-1.1	Q934G	Pathogenic	0.996
NPHS1	O60500-1.1	Q934H	Pathogenic	0.994
NPHS1	O60500-1.1	Q934I	Pathogenic	0.999
NPHS1	O60500-1.1	Q934K	Pathogenic	0.999
NPHS1	O60500-1.1	Q934L	Pathogenic	0.999
NPHS1	O60500-1.1	Q934M	Pathogenic	0.999
NPHS1	O60500-1.1	Q934N	Pathogenic	0.996
NPHS1	O60500-1.1	Q934P	Pathogenic	0.998
NPHS1	O60500-1.1	Q934R	Pathogenic	0.999
NPHS1	O60500-1.1	Q934S	Pathogenic	0.997
NPHS1	O60500-1.1	Q934T	Pathogenic	0.995
NPHS1	O60500-1.1	Q934V	Pathogenic	0.998
NPHS1	O60500-1.1	Q934W	Pathogenic	1.0
NPHS1	O60500-1.1	Q934Y	Pathogenic	0.998
NPHS1	O60500-1.1	L935A	Pathogenic	0.988
NPHS1	O60500-1.1	L935C	Pathogenic	0.949
NPHS1	O60500-1.1	L935D	Pathogenic	0.985
NPHS1	O60500-1.1	L935E	Pathogenic	0.982
NPHS1	O60500-1.1	L935F	Pathogenic	0.851
NPHS1	O60500-1.1	L935G	Pathogenic	0.983
NPHS1	O60500-1.1	L935H	Pathogenic	0.933
NPHS1	O60500-1.1	L935I	Pathogenic	0.909
NPHS1	O60500-1.1	L935K	Pathogenic	0.992
NPHS1	O60500-1.1	L935M	Pathogenic	0.945
NPHS1	O60500-1.1	L935N	Pathogenic	0.986
NPHS1	O60500-1.1	L935P	Pathogenic	0.918
NPHS1	O60500-1.1	L935Q	Pathogenic	0.975
NPHS1	O60500-1.1	L935R	Pathogenic	0.994
NPHS1	O60500-1.1	L935S	Pathogenic	0.987
NPHS1	O60500-1.1	L935T	Pathogenic	0.979
NPHS1	O60500-1.1	L935V	Pathogenic	0.949
NPHS1	O60500-1.1	L935W	Pathogenic	0.908
NPHS1	O60500-1.1	L935Y	Pathogenic	0.921
NPHS1	O60500-1.1	V936A	Pathogenic	0.933
NPHS1	O60500-1.1	V936C	Pathogenic	0.685
NPHS1	O60500-1.1	V936D	Pathogenic	0.922
NPHS1	O60500-1.1	V936E	Pathogenic	0.919
NPHS1	O60500-1.1	V936F	Pathogenic	0.823
NPHS1	O60500-1.1	V936G	Pathogenic	0.912
NPHS1	O60500-1.1	V936H	Pathogenic	0.75
NPHS1	O60500-1.1	V936I	Pathogenic	0.948
NPHS1	O60500-1.1	V936K	Pathogenic	0.973
NPHS1	O60500-1.1	V936L	Pathogenic	0.875
NPHS1	O60500-1.1	V936M	Pathogenic	0.777
NPHS1	O60500-1.1	V936N	Pathogenic	0.891
NPHS1	O60500-1.1	V936P	Pathogenic	0.663
NPHS1	O60500-1.1	V936Q	Pathogenic	0.873
NPHS1	O60500-1.1	V936R	Pathogenic	0.971
NPHS1	O60500-1.1	V936S	Pathogenic	0.9
NPHS1	O60500-1.1	V936T	Pathogenic	0.89
NPHS1	O60500-1.1	V936W	Pathogenic	0.89
NPHS1	O60500-1.1	V936Y	Pathogenic	0.77
NPHS1	O60500-1.1	S937A	Pathogenic	0.987
NPHS1	O60500-1.1	S937C	Pathogenic	0.991
NPHS1	O60500-1.1	S937D	Pathogenic	0.991
NPHS1	O60500-1.1	S937E	Pathogenic	0.993
NPHS1	O60500-1.1	S937F	Pathogenic	0.999
NPHS1	O60500-1.1	S937G	Pathogenic	0.98
NPHS1	O60500-1.1	S937H	Pathogenic	0.985
NPHS1	O60500-1.1	S937I	Pathogenic	0.998
NPHS1	O60500-1.1	S937K	Pathogenic	0.998
NPHS1	O60500-1.1	S937L	Pathogenic	0.998
NPHS1	O60500-1.1	S937M	Pathogenic	0.997
NPHS1	O60500-1.1	S937N	Pathogenic	0.993
NPHS1	O60500-1.1	S937P	Pathogenic	0.987
NPHS1	O60500-1.1	S937Q	Pathogenic	0.989
NPHS1	O60500-1.1	S937R	Pathogenic	0.998
NPHS1	O60500-1.1	S937T	Pathogenic	0.99
NPHS1	O60500-1.1	S937V	Pathogenic	0.994
NPHS1	O60500-1.1	S937W	Pathogenic	0.999
NPHS1	O60500-1.1	S937Y	Pathogenic	0.996
NPHS1	O60500-1.1	I938A	Pathogenic	0.992
NPHS1	O60500-1.1	I938C	Pathogenic	0.968
NPHS1	O60500-1.1	I938D	Pathogenic	0.994
NPHS1	O60500-1.1	I938E	Pathogenic	0.989
NPHS1	O60500-1.1	I938F	Pathogenic	0.879
NPHS1	O60500-1.1	I938G	Pathogenic	0.99
NPHS1	O60500-1.1	I938H	Pathogenic	0.958
NPHS1	O60500-1.1	I938K	Pathogenic	0.993
NPHS1	O60500-1.1	I938L	Pathogenic	0.934
NPHS1	O60500-1.1	I938M	Pathogenic	0.95
NPHS1	O60500-1.1	I938N	Pathogenic	0.991
NPHS1	O60500-1.1	I938P	Pathogenic	0.949
NPHS1	O60500-1.1	I938Q	Pathogenic	0.977
NPHS1	O60500-1.1	I938R	Pathogenic	0.995
NPHS1	O60500-1.1	I938S	Pathogenic	0.992
NPHS1	O60500-1.1	I938T	Pathogenic	0.987
NPHS1	O60500-1.1	I938V	Pathogenic	0.986
NPHS1	O60500-1.1	I938W	Pathogenic	0.89
NPHS1	O60500-1.1	I938Y	Pathogenic	0.951
NPHS1	O60500-1.1	S939A	Pathogenic	0.742
NPHS1	O60500-1.1	S939C	Pathogenic	0.807
NPHS1	O60500-1.1	S939D	Pathogenic	0.821
NPHS1	O60500-1.1	S939E	Pathogenic	0.852
NPHS1	O60500-1.1	S939F	Pathogenic	0.967
NPHS1	O60500-1.1	S939G	Pathogenic	0.657
NPHS1	O60500-1.1	S939H	Pathogenic	0.715
NPHS1	O60500-1.1	S939I	Pathogenic	0.959
NPHS1	O60500-1.1	S939K	Pathogenic	0.947
NPHS1	O60500-1.1	S939L	Pathogenic	0.952
NPHS1	O60500-1.1	S939M	Pathogenic	0.937
NPHS1	O60500-1.1	S939N	Pathogenic	0.857
NPHS1	O60500-1.1	S939P	Pathogenic	0.756
NPHS1	O60500-1.1	S939Q	Pathogenic	0.777
NPHS1	O60500-1.1	S939R	Pathogenic	0.944
NPHS1	O60500-1.1	S939T	Pathogenic	0.788
NPHS1	O60500-1.1	S939V	Pathogenic	0.861
NPHS1	O60500-1.1	S939W	Pathogenic	0.987
NPHS1	O60500-1.1	S939Y	Pathogenic	0.908
NPHS1	O60500-1.1	R940A	Pathogenic	0.969
NPHS1	O60500-1.1	R940C	Pathogenic	0.961
NPHS1	O60500-1.1	R940D	Pathogenic	0.706
NPHS1	O60500-1.1	R940E	Pathogenic	0.81
NPHS1	O60500-1.1	R940F	Pathogenic	0.963
NPHS1	O60500-1.1	R940G	Pathogenic	0.954
NPHS1	O60500-1.1	R940H	Pathogenic	0.915
NPHS1	O60500-1.1	R940I	Pathogenic	0.971
NPHS1	O60500-1.1	R940K	Pathogenic	0.752
NPHS1	O60500-1.1	R940L	Pathogenic	0.978
NPHS1	O60500-1.1	R940M	Pathogenic	0.97
NPHS1	O60500-1.1	R940N	Pathogenic	0.859
NPHS1	O60500-1.1	R940P	Pathogenic	0.958
NPHS1	O60500-1.1	R940Q	Pathogenic	0.913
NPHS1	O60500-1.1	R940S	Pathogenic	0.942
NPHS1	O60500-1.1	R940T	Pathogenic	0.94
NPHS1	O60500-1.1	R940V	Pathogenic	0.957
NPHS1	O60500-1.1	R940W	Pathogenic	0.982
NPHS1	O60500-1.1	R940Y	Pathogenic	0.906
NPHS1	O60500-1.1	P941A	Pathogenic	0.98
NPHS1	O60500-1.1	P941C	Pathogenic	0.918
NPHS1	O60500-1.1	P941D	Pathogenic	0.993
NPHS1	O60500-1.1	P941E	Pathogenic	0.994
NPHS1	O60500-1.1	P941F	Pathogenic	0.985
NPHS1	O60500-1.1	P941G	Pathogenic	0.988
NPHS1	O60500-1.1	P941H	Pathogenic	0.979
NPHS1	O60500-1.1	P941I	Pathogenic	0.987
NPHS1	O60500-1.1	P941K	Pathogenic	0.998
NPHS1	O60500-1.1	P941L	Pathogenic	0.985
NPHS1	O60500-1.1	P941M	Pathogenic	0.98
NPHS1	O60500-1.1	P941N	Pathogenic	0.988
NPHS1	O60500-1.1	P941Q	Pathogenic	0.991
NPHS1	O60500-1.1	P941R	Pathogenic	0.998
NPHS1	O60500-1.1	P941S	Pathogenic	0.986
NPHS1	O60500-1.1	P941T	Pathogenic	0.97
NPHS1	O60500-1.1	P941V	Pathogenic	0.968
NPHS1	O60500-1.1	P941W	Pathogenic	0.996
NPHS1	O60500-1.1	P941Y	Pathogenic	0.97
NPHS1	O60500-1.1	D942A	Pathogenic	0.992
NPHS1	O60500-1.1	D942C	Pathogenic	0.993
NPHS1	O60500-1.1	D942E	Pathogenic	0.992
NPHS1	O60500-1.1	D942F	Pathogenic	0.999
NPHS1	O60500-1.1	D942G	Pathogenic	0.994
NPHS1	O60500-1.1	D942H	Pathogenic	0.993
NPHS1	O60500-1.1	D942I	Pathogenic	0.999
NPHS1	O60500-1.1	D942K	Pathogenic	0.987
NPHS1	O60500-1.1	D942L	Pathogenic	0.998
NPHS1	O60500-1.1	D942M	Pathogenic	0.997
NPHS1	O60500-1.1	D942N	Pathogenic	0.985
NPHS1	O60500-1.1	D942P	Pathogenic	0.995
NPHS1	O60500-1.1	D942Q	Pathogenic	0.991
NPHS1	O60500-1.1	D942R	Pathogenic	0.986
NPHS1	O60500-1.1	D942S	Pathogenic	0.993
NPHS1	O60500-1.1	D942T	Pathogenic	0.99
NPHS1	O60500-1.1	D942V	Pathogenic	0.996
NPHS1	O60500-1.1	D942W	Pathogenic	1.0
NPHS1	O60500-1.1	D942Y	Pathogenic	0.997
NPHS1	O60500-1.1	P943A	Pathogenic	0.979
NPHS1	O60500-1.1	P943C	Pathogenic	0.916
NPHS1	O60500-1.1	P943D	Pathogenic	0.993
NPHS1	O60500-1.1	P943E	Pathogenic	0.994
NPHS1	O60500-1.1	P943F	Pathogenic	0.985
NPHS1	O60500-1.1	P943G	Pathogenic	0.987
NPHS1	O60500-1.1	P943H	Pathogenic	0.979
NPHS1	O60500-1.1	P943I	Pathogenic	0.987
NPHS1	O60500-1.1	P943K	Pathogenic	0.998
NPHS1	O60500-1.1	P943L	Pathogenic	0.985
NPHS1	O60500-1.1	P943M	Pathogenic	0.98
NPHS1	O60500-1.1	P943N	Pathogenic	0.988
NPHS1	O60500-1.1	P943Q	Pathogenic	0.991
NPHS1	O60500-1.1	P943R	Pathogenic	0.998
NPHS1	O60500-1.1	P943S	Pathogenic	0.986
NPHS1	O60500-1.1	P943T	Pathogenic	0.97
NPHS1	O60500-1.1	P943V	Pathogenic	0.968
NPHS1	O60500-1.1	P943W	Pathogenic	0.996
NPHS1	O60500-1.1	P943Y	Pathogenic	0.97
NPHS1	O60500-1.1	P944A	Pathogenic	0.945
NPHS1	O60500-1.1	P944C	Pathogenic	0.8
NPHS1	O60500-1.1	P944D	Pathogenic	0.981
NPHS1	O60500-1.1	P944E	Pathogenic	0.985
NPHS1	O60500-1.1	P944F	Pathogenic	0.959
NPHS1	O60500-1.1	P944G	Pathogenic	0.966
NPHS1	O60500-1.1	P944H	Pathogenic	0.944
NPHS1	O60500-1.1	P944I	Pathogenic	0.965
NPHS1	O60500-1.1	P944K	Pathogenic	0.995
NPHS1	O60500-1.1	P944L	Pathogenic	0.959
NPHS1	O60500-1.1	P944M	Pathogenic	0.946
NPHS1	O60500-1.1	P944N	Pathogenic	0.968
NPHS1	O60500-1.1	P944Q	Pathogenic	0.975
NPHS1	O60500-1.1	P944R	Pathogenic	0.995
NPHS1	O60500-1.1	P944S	Pathogenic	0.962
NPHS1	O60500-1.1	P944T	Pathogenic	0.921
NPHS1	O60500-1.1	P944V	Pathogenic	0.916
NPHS1	O60500-1.1	P944W	Pathogenic	0.989
NPHS1	O60500-1.1	P944Y	Pathogenic	0.921
NPHS1	O60500-1.1	S945A	Neutral	0.072
NPHS1	O60500-1.1	S945C	Neutral	0.101
NPHS1	O60500-1.1	S945D	Neutral	0.11
NPHS1	O60500-1.1	S945E	Neutral	0.135
NPHS1	O60500-1.1	S945F	Neutral	0.444
NPHS1	O60500-1.1	S945G	Neutral	0.049
NPHS1	O60500-1.1	S945H	Neutral	0.064
NPHS1	O60500-1.1	S945I	Neutral	0.387
NPHS1	O60500-1.1	S945K	Neutral	0.327
NPHS1	O60500-1.1	S945L	Neutral	0.351
NPHS1	O60500-1.1	S945M	Neutral	0.286
NPHS1	O60500-1.1	S945N	Neutral	0.139
NPHS1	O60500-1.1	S945P	Neutral	0.077
NPHS1	O60500-1.1	S945Q	Neutral	0.086
NPHS1	O60500-1.1	S945R	Neutral	0.312
NPHS1	O60500-1.1	S945T	Neutral	0.091
NPHS1	O60500-1.1	S945V	Neutral	0.144
NPHS1	O60500-1.1	S945W	Pathogenic	0.674
NPHS1	O60500-1.1	S945Y	Neutral	0.212
NPHS1	O60500-1.1	G946A	Pathogenic	0.685
NPHS1	O60500-1.1	G946C	Pathogenic	0.737
NPHS1	O60500-1.1	G946D	Pathogenic	0.836
NPHS1	O60500-1.1	G946E	Pathogenic	0.812
NPHS1	O60500-1.1	G946F	Pathogenic	0.967
NPHS1	O60500-1.1	G946H	Pathogenic	0.715
NPHS1	O60500-1.1	G946I	Pathogenic	0.94
NPHS1	O60500-1.1	G946K	Pathogenic	0.931
NPHS1	O60500-1.1	G946L	Pathogenic	0.931
NPHS1	O60500-1.1	G946M	Pathogenic	0.909
NPHS1	O60500-1.1	G946N	Pathogenic	0.87
NPHS1	O60500-1.1	G946P	Pathogenic	0.756
NPHS1	O60500-1.1	G946Q	Pathogenic	0.723
NPHS1	O60500-1.1	G946R	Pathogenic	0.949
NPHS1	O60500-1.1	G946S	Pathogenic	0.626
NPHS1	O60500-1.1	G946T	Pathogenic	0.626
NPHS1	O60500-1.1	G946V	Pathogenic	0.862
NPHS1	O60500-1.1	G946W	Pathogenic	0.994
NPHS1	O60500-1.1	G946Y	Pathogenic	0.909
NPHS1	O60500-1.1	L947A	Pathogenic	0.958
NPHS1	O60500-1.1	L947C	Pathogenic	0.843
NPHS1	O60500-1.1	L947D	Pathogenic	0.951
NPHS1	O60500-1.1	L947E	Pathogenic	0.94
NPHS1	O60500-1.1	L947F	Pathogenic	0.623
NPHS1	O60500-1.1	L947G	Pathogenic	0.945
NPHS1	O60500-1.1	L947H	Pathogenic	0.8
NPHS1	O60500-1.1	L947I	Pathogenic	0.743
NPHS1	O60500-1.1	L947K	Pathogenic	0.973
NPHS1	O60500-1.1	L947M	Pathogenic	0.833
NPHS1	O60500-1.1	L947N	Pathogenic	0.953
NPHS1	O60500-1.1	L947P	Pathogenic	0.764
NPHS1	O60500-1.1	L947Q	Pathogenic	0.917
NPHS1	O60500-1.1	L947R	Pathogenic	0.98
NPHS1	O60500-1.1	L947S	Pathogenic	0.957
NPHS1	O60500-1.1	L947T	Pathogenic	0.93
NPHS1	O60500-1.1	L947V	Pathogenic	0.843
NPHS1	O60500-1.1	L947W	Pathogenic	0.741
NPHS1	O60500-1.1	L947Y	Pathogenic	0.771
NPHS1	O60500-1.1	K948A	Pathogenic	0.991
NPHS1	O60500-1.1	K948C	Pathogenic	0.988
NPHS1	O60500-1.1	K948D	Pathogenic	0.925
NPHS1	O60500-1.1	K948E	Pathogenic	0.956
NPHS1	O60500-1.1	K948F	Pathogenic	0.989
NPHS1	O60500-1.1	K948G	Pathogenic	0.986
NPHS1	O60500-1.1	K948H	Pathogenic	0.962
NPHS1	O60500-1.1	K948I	Pathogenic	0.992
NPHS1	O60500-1.1	K948L	Pathogenic	0.993
NPHS1	O60500-1.1	K948M	Pathogenic	0.991
NPHS1	O60500-1.1	K948N	Pathogenic	0.955
NPHS1	O60500-1.1	K948P	Pathogenic	0.991
NPHS1	O60500-1.1	K948Q	Pathogenic	0.973
NPHS1	O60500-1.1	K948R	Pathogenic	0.936
NPHS1	O60500-1.1	K948S	Pathogenic	0.988
NPHS1	O60500-1.1	K948T	Pathogenic	0.982
NPHS1	O60500-1.1	K948V	Pathogenic	0.991
NPHS1	O60500-1.1	K948W	Pathogenic	0.997
NPHS1	O60500-1.1	K948Y	Pathogenic	0.978
NPHS1	O60500-1.1	V949A	Pathogenic	0.788
NPHS1	O60500-1.1	V949C	Neutral	0.368
NPHS1	O60500-1.1	V949D	Pathogenic	0.759
NPHS1	O60500-1.1	V949E	Pathogenic	0.753
NPHS1	O60500-1.1	V949F	Pathogenic	0.555
NPHS1	O60500-1.1	V949G	Pathogenic	0.735
NPHS1	O60500-1.1	V949H	Neutral	0.446
NPHS1	O60500-1.1	V949I	Pathogenic	0.829
NPHS1	O60500-1.1	V949K	Pathogenic	0.905
NPHS1	O60500-1.1	V949L	Pathogenic	0.652
NPHS1	O60500-1.1	V949M	Neutral	0.483
NPHS1	O60500-1.1	V949N	Pathogenic	0.685
NPHS1	O60500-1.1	V949P	Neutral	0.344
NPHS1	O60500-1.1	V949Q	Pathogenic	0.648
NPHS1	O60500-1.1	V949R	Pathogenic	0.899
NPHS1	O60500-1.1	V949S	Pathogenic	0.707
NPHS1	O60500-1.1	V949T	Pathogenic	0.684
NPHS1	O60500-1.1	V949W	Pathogenic	0.683
NPHS1	O60500-1.1	V949Y	Neutral	0.473
NPHS1	O60500-1.1	V950A	Pathogenic	0.895
NPHS1	O60500-1.1	V950C	Pathogenic	0.573
NPHS1	O60500-1.1	V950D	Pathogenic	0.879
NPHS1	O60500-1.1	V950E	Pathogenic	0.876
NPHS1	O60500-1.1	V950F	Pathogenic	0.742
NPHS1	O60500-1.1	V950G	Pathogenic	0.865
NPHS1	O60500-1.1	V950H	Pathogenic	0.65
NPHS1	O60500-1.1	V950I	Pathogenic	0.918
NPHS1	O60500-1.1	V950K	Pathogenic	0.956
NPHS1	O60500-1.1	V950L	Pathogenic	0.812
NPHS1	O60500-1.1	V950M	Pathogenic	0.683
NPHS1	O60500-1.1	V950N	Pathogenic	0.834
NPHS1	O60500-1.1	V950P	Pathogenic	0.548
NPHS1	O60500-1.1	V950Q	Pathogenic	0.81
NPHS1	O60500-1.1	V950R	Pathogenic	0.953
NPHS1	O60500-1.1	V950S	Pathogenic	0.848
NPHS1	O60500-1.1	V950T	Pathogenic	0.833
NPHS1	O60500-1.1	V950W	Pathogenic	0.833
NPHS1	O60500-1.1	V950Y	Pathogenic	0.675
NPHS1	O60500-1.1	S951A	Pathogenic	0.639
NPHS1	O60500-1.1	S951C	Pathogenic	0.72
NPHS1	O60500-1.1	S951D	Pathogenic	0.738
NPHS1	O60500-1.1	S951E	Pathogenic	0.78
NPHS1	O60500-1.1	S951F	Pathogenic	0.948
NPHS1	O60500-1.1	S951G	Pathogenic	0.541
NPHS1	O60500-1.1	S951H	Pathogenic	0.607
NPHS1	O60500-1.1	S951I	Pathogenic	0.935
NPHS1	O60500-1.1	S951K	Pathogenic	0.917
NPHS1	O60500-1.1	S951L	Pathogenic	0.925
NPHS1	O60500-1.1	S951M	Pathogenic	0.901
NPHS1	O60500-1.1	S951N	Pathogenic	0.786
NPHS1	O60500-1.1	S951P	Pathogenic	0.656
NPHS1	O60500-1.1	S951Q	Pathogenic	0.681
NPHS1	O60500-1.1	S951R	Pathogenic	0.911
NPHS1	O60500-1.1	S951T	Pathogenic	0.696
NPHS1	O60500-1.1	S951V	Pathogenic	0.793
NPHS1	O60500-1.1	S951W	Pathogenic	0.979
NPHS1	O60500-1.1	S951Y	Pathogenic	0.859
NPHS1	O60500-1.1	L952A	Neutral	0.011
NPHS1	O60500-1.1	L952C	Neutral	0.003
NPHS1	O60500-1.1	L952D	Neutral	0.009
NPHS1	O60500-1.1	L952E	Neutral	0.007
NPHS1	O60500-1.1	L952F	Neutral	0.001
NPHS1	O60500-1.1	L952G	Neutral	0.008
NPHS1	O60500-1.1	L952H	Neutral	0.002
NPHS1	O60500-1.1	L952I	Neutral	0.001
NPHS1	O60500-1.1	L952K	Neutral	0.016
NPHS1	O60500-1.1	L952M	Neutral	0.002
NPHS1	O60500-1.1	L952N	Neutral	0.009
NPHS1	O60500-1.1	L952P	Neutral	0.002
NPHS1	O60500-1.1	L952Q	Neutral	0.005
NPHS1	O60500-1.1	L952R	Neutral	0.023
NPHS1	O60500-1.1	L952S	Neutral	0.01
NPHS1	O60500-1.1	L952T	Neutral	0.006
NPHS1	O60500-1.1	L952V	Neutral	0.003
NPHS1	O60500-1.1	L952W	Neutral	0.001
NPHS1	O60500-1.1	L952Y	Neutral	0.002
NPHS1	O60500-1.1	T953A	Pathogenic	0.799
NPHS1	O60500-1.1	T953C	Pathogenic	0.823
NPHS1	O60500-1.1	T953D	Pathogenic	0.866
NPHS1	O60500-1.1	T953E	Pathogenic	0.881
NPHS1	O60500-1.1	T953F	Pathogenic	0.959
NPHS1	O60500-1.1	T953G	Pathogenic	0.792
NPHS1	O60500-1.1	T953H	Pathogenic	0.661
NPHS1	O60500-1.1	T953I	Pathogenic	0.965
NPHS1	O60500-1.1	T953K	Pathogenic	0.958
NPHS1	O60500-1.1	T953L	Pathogenic	0.96
NPHS1	O60500-1.1	T953M	Pathogenic	0.922
NPHS1	O60500-1.1	T953N	Pathogenic	0.885
NPHS1	O60500-1.1	T953P	Pathogenic	0.741
NPHS1	O60500-1.1	T953Q	Pathogenic	0.817
NPHS1	O60500-1.1	T953R	Pathogenic	0.97
NPHS1	O60500-1.1	T953S	Pathogenic	0.881
NPHS1	O60500-1.1	T953V	Pathogenic	0.917
NPHS1	O60500-1.1	T953W	Pathogenic	0.989
NPHS1	O60500-1.1	T953Y	Pathogenic	0.888
NPHS1	O60500-1.1	P954A	Neutral	0.476
NPHS1	O60500-1.1	P954C	Neutral	0.173
NPHS1	O60500-1.1	P954D	Pathogenic	0.728
NPHS1	O60500-1.1	P954E	Pathogenic	0.771
NPHS1	O60500-1.1	P954F	Pathogenic	0.551
NPHS1	O60500-1.1	P954G	Pathogenic	0.601
NPHS1	O60500-1.1	P954H	Neutral	0.471
NPHS1	O60500-1.1	P954I	Pathogenic	0.591
NPHS1	O60500-1.1	P954K	Pathogenic	0.913
NPHS1	O60500-1.1	P954L	Pathogenic	0.553
NPHS1	O60500-1.1	P954M	Neutral	0.479
NPHS1	O60500-1.1	P954N	Pathogenic	0.612
NPHS1	O60500-1.1	P954Q	Pathogenic	0.671
NPHS1	O60500-1.1	P954R	Pathogenic	0.907
NPHS1	O60500-1.1	P954S	Pathogenic	0.568
NPHS1	O60500-1.1	P954T	Neutral	0.379
NPHS1	O60500-1.1	P954V	Neutral	0.365
NPHS1	O60500-1.1	P954W	Pathogenic	0.826
NPHS1	O60500-1.1	P954Y	Neutral	0.381
NPHS1	O60500-1.1	H955A	Neutral	0.167
NPHS1	O60500-1.1	H955C	Neutral	0.189
NPHS1	O60500-1.1	H955D	Neutral	0.332
NPHS1	O60500-1.1	H955E	Neutral	0.285
NPHS1	O60500-1.1	H955F	Pathogenic	0.547
NPHS1	O60500-1.1	H955G	Neutral	0.227
NPHS1	O60500-1.1	H955I	Neutral	0.3
NPHS1	O60500-1.1	H955K	Neutral	0.353
NPHS1	O60500-1.1	H955L	Neutral	0.269
NPHS1	O60500-1.1	H955M	Neutral	0.214
NPHS1	O60500-1.1	H955N	Neutral	0.434
NPHS1	O60500-1.1	H955P	Neutral	0.176
NPHS1	O60500-1.1	H955Q	Neutral	0.16
NPHS1	O60500-1.1	H955R	Pathogenic	0.53
NPHS1	O60500-1.1	H955S	Neutral	0.204
NPHS1	O60500-1.1	H955T	Neutral	0.091
NPHS1	O60500-1.1	H955V	Neutral	0.174
NPHS1	O60500-1.1	H955W	Pathogenic	0.757
NPHS1	O60500-1.1	H955Y	Pathogenic	0.574
NPHS1	O60500-1.1	S956A	Pathogenic	0.943
NPHS1	O60500-1.1	S956C	Pathogenic	0.96
NPHS1	O60500-1.1	S956D	Pathogenic	0.963
NPHS1	O60500-1.1	S956E	Pathogenic	0.971
NPHS1	O60500-1.1	S956F	Pathogenic	0.994
NPHS1	O60500-1.1	S956G	Pathogenic	0.916
NPHS1	O60500-1.1	S956H	Pathogenic	0.935
NPHS1	O60500-1.1	S956I	Pathogenic	0.993
NPHS1	O60500-1.1	S956K	Pathogenic	0.99
NPHS1	O60500-1.1	S956L	Pathogenic	0.991
NPHS1	O60500-1.1	S956M	Pathogenic	0.988
NPHS1	O60500-1.1	S956N	Pathogenic	0.972
NPHS1	O60500-1.1	S956P	Pathogenic	0.947
NPHS1	O60500-1.1	S956Q	Pathogenic	0.952
NPHS1	O60500-1.1	S956R	Pathogenic	0.99
NPHS1	O60500-1.1	S956T	Pathogenic	0.955
NPHS1	O60500-1.1	S956V	Pathogenic	0.973
NPHS1	O60500-1.1	S956W	Pathogenic	0.998
NPHS1	O60500-1.1	S956Y	Pathogenic	0.983
NPHS1	O60500-1.1	V957A	Pathogenic	0.784
NPHS1	O60500-1.1	V957C	Neutral	0.363
NPHS1	O60500-1.1	V957D	Pathogenic	0.756
NPHS1	O60500-1.1	V957E	Pathogenic	0.749
NPHS1	O60500-1.1	V957F	Pathogenic	0.55
NPHS1	O60500-1.1	V957G	Pathogenic	0.731
NPHS1	O60500-1.1	V957H	Neutral	0.441
NPHS1	O60500-1.1	V957I	Pathogenic	0.827
NPHS1	O60500-1.1	V957K	Pathogenic	0.903
NPHS1	O60500-1.1	V957L	Pathogenic	0.648
NPHS1	O60500-1.1	V957M	Neutral	0.478
NPHS1	O60500-1.1	V957N	Pathogenic	0.681
NPHS1	O60500-1.1	V957P	Neutral	0.34
NPHS1	O60500-1.1	V957Q	Pathogenic	0.644
NPHS1	O60500-1.1	V957R	Pathogenic	0.897
NPHS1	O60500-1.1	V957S	Pathogenic	0.703
NPHS1	O60500-1.1	V957T	Pathogenic	0.68
NPHS1	O60500-1.1	V957W	Pathogenic	0.679
NPHS1	O60500-1.1	V957Y	Neutral	0.468
NPHS1	O60500-1.1	G958A	Neutral	0.226
NPHS1	O60500-1.1	G958C	Neutral	0.274
NPHS1	O60500-1.1	G958D	Neutral	0.408
NPHS1	O60500-1.1	G958E	Neutral	0.367
NPHS1	O60500-1.1	G958F	Pathogenic	0.799
NPHS1	O60500-1.1	G958H	Neutral	0.253
NPHS1	O60500-1.1	G958I	Pathogenic	0.678
NPHS1	O60500-1.1	G958K	Pathogenic	0.644
NPHS1	O60500-1.1	G958L	Pathogenic	0.644
NPHS1	O60500-1.1	G958M	Pathogenic	0.573
NPHS1	O60500-1.1	G958N	Neutral	0.473
NPHS1	O60500-1.1	G958P	Neutral	0.295
NPHS1	O60500-1.1	G958Q	Neutral	0.26
NPHS1	O60500-1.1	G958R	Pathogenic	0.716
NPHS1	O60500-1.1	G958S	Neutral	0.184
NPHS1	O60500-1.1	G958T	Neutral	0.184
NPHS1	O60500-1.1	G958V	Neutral	0.456
NPHS1	O60500-1.1	G958W	Pathogenic	0.958
NPHS1	O60500-1.1	G958Y	Pathogenic	0.572
NPHS1	O60500-1.1	L959A	Pathogenic	0.993
NPHS1	O60500-1.1	L959C	Pathogenic	0.972
NPHS1	O60500-1.1	L959D	Pathogenic	0.992
NPHS1	O60500-1.1	L959E	Pathogenic	0.99
NPHS1	O60500-1.1	L959F	Pathogenic	0.915
NPHS1	O60500-1.1	L959G	Pathogenic	0.991
NPHS1	O60500-1.1	L959H	Pathogenic	0.963
NPHS1	O60500-1.1	L959I	Pathogenic	0.95
NPHS1	O60500-1.1	L959K	Pathogenic	0.996
NPHS1	O60500-1.1	L959M	Pathogenic	0.97
NPHS1	O60500-1.1	L959N	Pathogenic	0.992
NPHS1	O60500-1.1	L959P	Pathogenic	0.955
NPHS1	O60500-1.1	L959Q	Pathogenic	0.986
NPHS1	O60500-1.1	L959R	Pathogenic	0.997
NPHS1	O60500-1.1	L959S	Pathogenic	0.993
NPHS1	O60500-1.1	L959T	Pathogenic	0.989
NPHS1	O60500-1.1	L959V	Pathogenic	0.972
NPHS1	O60500-1.1	L959W	Pathogenic	0.949
NPHS1	O60500-1.1	L959Y	Pathogenic	0.957
NPHS1	O60500-1.1	E960A	Pathogenic	0.671
NPHS1	O60500-1.1	E960C	Pathogenic	0.517
NPHS1	O60500-1.1	E960D	Pathogenic	0.534
NPHS1	O60500-1.1	E960F	Pathogenic	0.851
NPHS1	O60500-1.1	E960G	Pathogenic	0.576
NPHS1	O60500-1.1	E960H	Pathogenic	0.518
NPHS1	O60500-1.1	E960I	Pathogenic	0.818
NPHS1	O60500-1.1	E960K	Pathogenic	0.562
NPHS1	O60500-1.1	E960L	Pathogenic	0.794
NPHS1	O60500-1.1	E960M	Pathogenic	0.741
NPHS1	O60500-1.1	E960N	Neutral	0.284
NPHS1	O60500-1.1	E960P	Pathogenic	0.686
NPHS1	O60500-1.1	E960Q	Pathogenic	0.563
NPHS1	O60500-1.1	E960R	Pathogenic	0.545
NPHS1	O60500-1.1	E960S	Pathogenic	0.613
NPHS1	O60500-1.1	E960T	Pathogenic	0.506
NPHS1	O60500-1.1	E960V	Pathogenic	0.683
NPHS1	O60500-1.1	E960W	Pathogenic	0.956
NPHS1	O60500-1.1	E960Y	Pathogenic	0.741
NPHS1	O60500-1.1	W961A	Pathogenic	1.0
NPHS1	O60500-1.1	W961C	Pathogenic	1.0
NPHS1	O60500-1.1	W961D	Pathogenic	1.0
NPHS1	O60500-1.1	W961E	Pathogenic	1.0
NPHS1	O60500-1.1	W961F	Pathogenic	0.999
NPHS1	O60500-1.1	W961G	Pathogenic	1.0
NPHS1	O60500-1.1	W961H	Pathogenic	1.0
NPHS1	O60500-1.1	W961I	Pathogenic	0.995
NPHS1	O60500-1.1	W961K	Pathogenic	1.0
NPHS1	O60500-1.1	W961L	Pathogenic	0.997
NPHS1	O60500-1.1	W961M	Pathogenic	0.999
NPHS1	O60500-1.1	W961N	Pathogenic	1.0
NPHS1	O60500-1.1	W961P	Pathogenic	0.999
NPHS1	O60500-1.1	W961Q	Pathogenic	1.0
NPHS1	O60500-1.1	W961R	Pathogenic	1.0
NPHS1	O60500-1.1	W961S	Pathogenic	1.0
NPHS1	O60500-1.1	W961T	Pathogenic	1.0
NPHS1	O60500-1.1	W961V	Pathogenic	0.999
NPHS1	O60500-1.1	W961Y	Pathogenic	1.0
NPHS1	O60500-1.1	K962A	Pathogenic	0.916
NPHS1	O60500-1.1	K962C	Pathogenic	0.895
NPHS1	O60500-1.1	K962D	Pathogenic	0.554
NPHS1	O60500-1.1	K962E	Pathogenic	0.687
NPHS1	O60500-1.1	K962F	Pathogenic	0.899
NPHS1	O60500-1.1	K962G	Pathogenic	0.879
NPHS1	O60500-1.1	K962H	Pathogenic	0.715
NPHS1	O60500-1.1	K962I	Pathogenic	0.922
NPHS1	O60500-1.1	K962L	Pathogenic	0.938
NPHS1	O60500-1.1	K962M	Pathogenic	0.918
NPHS1	O60500-1.1	K962N	Pathogenic	0.679
NPHS1	O60500-1.1	K962P	Pathogenic	0.921
NPHS1	O60500-1.1	K962Q	Pathogenic	0.784
NPHS1	O60500-1.1	K962R	Pathogenic	0.594
NPHS1	O60500-1.1	K962S	Pathogenic	0.894
NPHS1	O60500-1.1	K962T	Pathogenic	0.845
NPHS1	O60500-1.1	K962V	Pathogenic	0.92
NPHS1	O60500-1.1	K962W	Pathogenic	0.972
NPHS1	O60500-1.1	K962Y	Pathogenic	0.817
NPHS1	O60500-1.1	P963A	Neutral	0.341
NPHS1	O60500-1.1	P963C	Neutral	0.107
NPHS1	O60500-1.1	P963D	Pathogenic	0.605
NPHS1	O60500-1.1	P963E	Pathogenic	0.658
NPHS1	O60500-1.1	P963F	Neutral	0.412
NPHS1	O60500-1.1	P963G	Neutral	0.463
NPHS1	O60500-1.1	P963H	Neutral	0.337
NPHS1	O60500-1.1	P963I	Neutral	0.452
NPHS1	O60500-1.1	P963K	Pathogenic	0.857
NPHS1	O60500-1.1	P963L	Neutral	0.415
NPHS1	O60500-1.1	P963M	Neutral	0.344
NPHS1	O60500-1.1	P963N	Neutral	0.474
NPHS1	O60500-1.1	P963Q	Pathogenic	0.538
NPHS1	O60500-1.1	P963R	Pathogenic	0.849
NPHS1	O60500-1.1	P963S	Neutral	0.429
NPHS1	O60500-1.1	P963T	Neutral	0.259
NPHS1	O60500-1.1	P963V	Neutral	0.247
NPHS1	O60500-1.1	P963W	Pathogenic	0.73
NPHS1	O60500-1.1	P963Y	Neutral	0.26
NPHS1	O60500-1.1	G964A	Pathogenic	0.953
NPHS1	O60500-1.1	G964C	Pathogenic	0.963
NPHS1	O60500-1.1	G964D	Pathogenic	0.98
NPHS1	O60500-1.1	G964E	Pathogenic	0.976
NPHS1	O60500-1.1	G964F	Pathogenic	0.996
NPHS1	O60500-1.1	G964H	Pathogenic	0.959
NPHS1	O60500-1.1	G964I	Pathogenic	0.993
NPHS1	O60500-1.1	G964K	Pathogenic	0.992
NPHS1	O60500-1.1	G964L	Pathogenic	0.992
NPHS1	O60500-1.1	G964M	Pathogenic	0.989
NPHS1	O60500-1.1	G964N	Pathogenic	0.984
NPHS1	O60500-1.1	G964P	Pathogenic	0.967
NPHS1	O60500-1.1	G964Q	Pathogenic	0.961
NPHS1	O60500-1.1	G964R	Pathogenic	0.994
NPHS1	O60500-1.1	G964S	Pathogenic	0.94
NPHS1	O60500-1.1	G964T	Pathogenic	0.94
NPHS1	O60500-1.1	G964V	Pathogenic	0.983
NPHS1	O60500-1.1	G964W	Pathogenic	0.999
NPHS1	O60500-1.1	G964Y	Pathogenic	0.989
NPHS1	O60500-1.1	F965A	Pathogenic	0.999
NPHS1	O60500-1.1	F965C	Pathogenic	0.998
NPHS1	O60500-1.1	F965D	Pathogenic	1.0
NPHS1	O60500-1.1	F965E	Pathogenic	0.999
NPHS1	O60500-1.1	F965G	Pathogenic	1.0
NPHS1	O60500-1.1	F965H	Pathogenic	0.999
NPHS1	O60500-1.1	F965I	Pathogenic	0.992
NPHS1	O60500-1.1	F965K	Pathogenic	0.999
NPHS1	O60500-1.1	F965L	Pathogenic	0.992
NPHS1	O60500-1.1	F965M	Pathogenic	0.996
NPHS1	O60500-1.1	F965N	Pathogenic	1.0
NPHS1	O60500-1.1	F965P	Pathogenic	0.996
NPHS1	O60500-1.1	F965Q	Pathogenic	0.999
NPHS1	O60500-1.1	F965R	Pathogenic	1.0
NPHS1	O60500-1.1	F965S	Pathogenic	1.0
NPHS1	O60500-1.1	F965T	Pathogenic	0.999
NPHS1	O60500-1.1	F965V	Pathogenic	0.996
NPHS1	O60500-1.1	F965W	Pathogenic	0.998
NPHS1	O60500-1.1	F965Y	Pathogenic	0.999
NPHS1	O60500-1.1	D966A	Pathogenic	0.958
NPHS1	O60500-1.1	D966C	Pathogenic	0.963
NPHS1	O60500-1.1	D966E	Pathogenic	0.959
NPHS1	O60500-1.1	D966F	Pathogenic	0.995
NPHS1	O60500-1.1	D966G	Pathogenic	0.971
NPHS1	O60500-1.1	D966H	Pathogenic	0.965
NPHS1	O60500-1.1	D966I	Pathogenic	0.994
NPHS1	O60500-1.1	D966K	Pathogenic	0.938
NPHS1	O60500-1.1	D966L	Pathogenic	0.99
NPHS1	O60500-1.1	D966M	Pathogenic	0.987
NPHS1	O60500-1.1	D966N	Pathogenic	0.925
NPHS1	O60500-1.1	D966P	Pathogenic	0.973
NPHS1	O60500-1.1	D966Q	Pathogenic	0.957
NPHS1	O60500-1.1	D966R	Pathogenic	0.933
NPHS1	O60500-1.1	D966S	Pathogenic	0.963
NPHS1	O60500-1.1	D966T	Pathogenic	0.949
NPHS1	O60500-1.1	D966V	Pathogenic	0.979
NPHS1	O60500-1.1	D966W	Pathogenic	0.998
NPHS1	O60500-1.1	D966Y	Pathogenic	0.987
NPHS1	O60500-1.1	G967A	Pathogenic	0.965
NPHS1	O60500-1.1	G967C	Pathogenic	0.972
NPHS1	O60500-1.1	G967D	Pathogenic	0.985
NPHS1	O60500-1.1	G967E	Pathogenic	0.982
NPHS1	O60500-1.1	G967F	Pathogenic	0.997
NPHS1	O60500-1.1	G967H	Pathogenic	0.969
NPHS1	O60500-1.1	G967I	Pathogenic	0.995
NPHS1	O60500-1.1	G967K	Pathogenic	0.994
NPHS1	O60500-1.1	G967L	Pathogenic	0.994
NPHS1	O60500-1.1	G967M	Pathogenic	0.992
NPHS1	O60500-1.1	G967N	Pathogenic	0.988
NPHS1	O60500-1.1	G967P	Pathogenic	0.975
NPHS1	O60500-1.1	G967Q	Pathogenic	0.97
NPHS1	O60500-1.1	G967R	Pathogenic	0.996
NPHS1	O60500-1.1	G967S	Pathogenic	0.955
NPHS1	O60500-1.1	G967T	Pathogenic	0.955
NPHS1	O60500-1.1	G967V	Pathogenic	0.987
NPHS1	O60500-1.1	G967W	Pathogenic	1.0
NPHS1	O60500-1.1	G967Y	Pathogenic	0.992
NPHS1	O60500-1.1	G968A	Pathogenic	0.974
NPHS1	O60500-1.1	G968C	Pathogenic	0.98
NPHS1	O60500-1.1	G968D	Pathogenic	0.989
NPHS1	O60500-1.1	G968E	Pathogenic	0.987
NPHS1	O60500-1.1	G968F	Pathogenic	0.998
NPHS1	O60500-1.1	G968H	Pathogenic	0.977
NPHS1	O60500-1.1	G968I	Pathogenic	0.996
NPHS1	O60500-1.1	G968K	Pathogenic	0.996
NPHS1	O60500-1.1	G968L	Pathogenic	0.996
NPHS1	O60500-1.1	G968M	Pathogenic	0.994
NPHS1	O60500-1.1	G968N	Pathogenic	0.991
NPHS1	O60500-1.1	G968P	Pathogenic	0.982
NPHS1	O60500-1.1	G968Q	Pathogenic	0.978
NPHS1	O60500-1.1	G968R	Pathogenic	0.997
NPHS1	O60500-1.1	G968S	Pathogenic	0.966
NPHS1	O60500-1.1	G968T	Pathogenic	0.966
NPHS1	O60500-1.1	G968V	Pathogenic	0.991
NPHS1	O60500-1.1	G968W	Pathogenic	1.0
NPHS1	O60500-1.1	G968Y	Pathogenic	0.994
NPHS1	O60500-1.1	L969A	Pathogenic	0.976
NPHS1	O60500-1.1	L969C	Pathogenic	0.905
NPHS1	O60500-1.1	L969D	Pathogenic	0.972
NPHS1	O60500-1.1	L969E	Pathogenic	0.965
NPHS1	O60500-1.1	L969F	Pathogenic	0.745
NPHS1	O60500-1.1	L969G	Pathogenic	0.968
NPHS1	O60500-1.1	L969H	Pathogenic	0.877
NPHS1	O60500-1.1	L969I	Pathogenic	0.837
NPHS1	O60500-1.1	L969K	Pathogenic	0.984
NPHS1	O60500-1.1	L969M	Pathogenic	0.899
NPHS1	O60500-1.1	L969N	Pathogenic	0.973
NPHS1	O60500-1.1	L969P	Pathogenic	0.852
NPHS1	O60500-1.1	L969Q	Pathogenic	0.952
NPHS1	O60500-1.1	L969R	Pathogenic	0.989
NPHS1	O60500-1.1	L969S	Pathogenic	0.975
NPHS1	O60500-1.1	L969T	Pathogenic	0.96
NPHS1	O60500-1.1	L969V	Pathogenic	0.905
NPHS1	O60500-1.1	L969W	Pathogenic	0.835
NPHS1	O60500-1.1	L969Y	Pathogenic	0.857
NPHS1	O60500-1.1	P970A	Neutral	0.193
NPHS1	O60500-1.1	P970C	Neutral	0.052
NPHS1	O60500-1.1	P970D	Neutral	0.414
NPHS1	O60500-1.1	P970E	Neutral	0.47
NPHS1	O60500-1.1	P970F	Neutral	0.244
NPHS1	O60500-1.1	P970G	Neutral	0.284
NPHS1	O60500-1.1	P970H	Neutral	0.19
NPHS1	O60500-1.1	P970I	Neutral	0.275
NPHS1	O60500-1.1	P970K	Pathogenic	0.735
NPHS1	O60500-1.1	P970L	Neutral	0.246
NPHS1	O60500-1.1	P970M	Neutral	0.195
NPHS1	O60500-1.1	P970N	Neutral	0.293
NPHS1	O60500-1.1	P970Q	Neutral	0.349
NPHS1	O60500-1.1	P970R	Pathogenic	0.721
NPHS1	O60500-1.1	P970S	Neutral	0.257
NPHS1	O60500-1.1	P970T	Neutral	0.138
NPHS1	O60500-1.1	P970V	Neutral	0.131
NPHS1	O60500-1.1	P970W	Pathogenic	0.555
NPHS1	O60500-1.1	P970Y	Neutral	0.139
NPHS1	O60500-1.1	Q971A	Pathogenic	0.993
NPHS1	O60500-1.1	Q971C	Pathogenic	0.991
NPHS1	O60500-1.1	Q971D	Pathogenic	0.992
NPHS1	O60500-1.1	Q971E	Pathogenic	0.994
NPHS1	O60500-1.1	Q971F	Pathogenic	0.997
NPHS1	O60500-1.1	Q971G	Pathogenic	0.99
NPHS1	O60500-1.1	Q971H	Pathogenic	0.984
NPHS1	O60500-1.1	Q971I	Pathogenic	0.996
NPHS1	O60500-1.1	Q971K	Pathogenic	0.996
NPHS1	O60500-1.1	Q971L	Pathogenic	0.997
NPHS1	O60500-1.1	Q971M	Pathogenic	0.997
NPHS1	O60500-1.1	Q971N	Pathogenic	0.989
NPHS1	O60500-1.1	Q971P	Pathogenic	0.994
NPHS1	O60500-1.1	Q971R	Pathogenic	0.997
NPHS1	O60500-1.1	Q971S	Pathogenic	0.991
NPHS1	O60500-1.1	Q971T	Pathogenic	0.987
NPHS1	O60500-1.1	Q971V	Pathogenic	0.994
NPHS1	O60500-1.1	Q971W	Pathogenic	0.999
NPHS1	O60500-1.1	Q971Y	Pathogenic	0.996
NPHS1	O60500-1.1	R972A	Pathogenic	0.85
NPHS1	O60500-1.1	R972C	Pathogenic	0.816
NPHS1	O60500-1.1	R972D	Neutral	0.302
NPHS1	O60500-1.1	R972E	Neutral	0.433
NPHS1	O60500-1.1	R972F	Pathogenic	0.822
NPHS1	O60500-1.1	R972G	Pathogenic	0.79
NPHS1	O60500-1.1	R972H	Pathogenic	0.66
NPHS1	O60500-1.1	R972I	Pathogenic	0.86
NPHS1	O60500-1.1	R972K	Neutral	0.353
NPHS1	O60500-1.1	R972L	Pathogenic	0.887
NPHS1	O60500-1.1	R972M	Pathogenic	0.853
NPHS1	O60500-1.1	R972N	Pathogenic	0.523
NPHS1	O60500-1.1	R972P	Pathogenic	0.802
NPHS1	O60500-1.1	R972Q	Pathogenic	0.654
NPHS1	O60500-1.1	R972S	Pathogenic	0.746
NPHS1	O60500-1.1	R972T	Pathogenic	0.739
NPHS1	O60500-1.1	R972V	Pathogenic	0.8
NPHS1	O60500-1.1	R972W	Pathogenic	0.906
NPHS1	O60500-1.1	R972Y	Pathogenic	0.635
NPHS1	O60500-1.1	F973A	Pathogenic	0.998
NPHS1	O60500-1.1	F973C	Pathogenic	0.994
NPHS1	O60500-1.1	F973D	Pathogenic	0.999
NPHS1	O60500-1.1	F973E	Pathogenic	0.999
NPHS1	O60500-1.1	F973G	Pathogenic	0.999
NPHS1	O60500-1.1	F973H	Pathogenic	0.997
NPHS1	O60500-1.1	F973I	Pathogenic	0.977
NPHS1	O60500-1.1	F973K	Pathogenic	0.998
NPHS1	O60500-1.1	F973L	Pathogenic	0.979
NPHS1	O60500-1.1	F973M	Pathogenic	0.99
NPHS1	O60500-1.1	F973N	Pathogenic	0.999
NPHS1	O60500-1.1	F973P	Pathogenic	0.989
NPHS1	O60500-1.1	F973Q	Pathogenic	0.997
NPHS1	O60500-1.1	F973R	Pathogenic	0.999
NPHS1	O60500-1.1	F973S	Pathogenic	0.999
NPHS1	O60500-1.1	F973T	Pathogenic	0.997
NPHS1	O60500-1.1	F973V	Pathogenic	0.99
NPHS1	O60500-1.1	F973W	Pathogenic	0.995
NPHS1	O60500-1.1	F973Y	Pathogenic	0.998
NPHS1	O60500-1.1	C974A	Neutral	0.137
NPHS1	O60500-1.1	C974D	Neutral	0.146
NPHS1	O60500-1.1	C974E	Neutral	0.126
NPHS1	O60500-1.1	C974F	Neutral	0.15
NPHS1	O60500-1.1	C974G	Neutral	0.106
NPHS1	O60500-1.1	C974H	Neutral	0.078
NPHS1	O60500-1.1	C974I	Neutral	0.172
NPHS1	O60500-1.1	C974K	Neutral	0.402
NPHS1	O60500-1.1	C974L	Neutral	0.151
NPHS1	O60500-1.1	C974M	Neutral	0.082
NPHS1	O60500-1.1	C974N	Neutral	0.13
NPHS1	O60500-1.1	C974P	Neutral	0.018
NPHS1	O60500-1.1	C974Q	Neutral	0.115
NPHS1	O60500-1.1	C974R	Neutral	0.483
NPHS1	O60500-1.1	C974S	Neutral	0.134
NPHS1	O60500-1.1	C974T	Neutral	0.08
NPHS1	O60500-1.1	C974V	Neutral	0.053
NPHS1	O60500-1.1	C974W	Neutral	0.405
NPHS1	O60500-1.1	C974Y	Neutral	0.06
NPHS1	O60500-1.1	I975A	Pathogenic	0.989
NPHS1	O60500-1.1	I975C	Pathogenic	0.956
NPHS1	O60500-1.1	I975D	Pathogenic	0.992
NPHS1	O60500-1.1	I975E	Pathogenic	0.984
NPHS1	O60500-1.1	I975F	Pathogenic	0.838
NPHS1	O60500-1.1	I975G	Pathogenic	0.986
NPHS1	O60500-1.1	I975H	Pathogenic	0.942
NPHS1	O60500-1.1	I975K	Pathogenic	0.99
NPHS1	O60500-1.1	I975L	Pathogenic	0.91
NPHS1	O60500-1.1	I975M	Pathogenic	0.931
NPHS1	O60500-1.1	I975N	Pathogenic	0.988
NPHS1	O60500-1.1	I975P	Pathogenic	0.929
NPHS1	O60500-1.1	I975Q	Pathogenic	0.968
NPHS1	O60500-1.1	I975R	Pathogenic	0.993
NPHS1	O60500-1.1	I975S	Pathogenic	0.989
NPHS1	O60500-1.1	I975T	Pathogenic	0.982
NPHS1	O60500-1.1	I975V	Pathogenic	0.98
NPHS1	O60500-1.1	I975W	Pathogenic	0.852
NPHS1	O60500-1.1	I975Y	Pathogenic	0.932
NPHS1	O60500-1.1	R976A	Pathogenic	0.998
NPHS1	O60500-1.1	R976C	Pathogenic	0.998
NPHS1	O60500-1.1	R976D	Pathogenic	0.978
NPHS1	O60500-1.1	R976E	Pathogenic	0.987
NPHS1	O60500-1.1	R976F	Pathogenic	0.998
NPHS1	O60500-1.1	R976G	Pathogenic	0.997
NPHS1	O60500-1.1	R976H	Pathogenic	0.995
NPHS1	O60500-1.1	R976I	Pathogenic	0.998
NPHS1	O60500-1.1	R976K	Pathogenic	0.982
NPHS1	O60500-1.1	R976L	Pathogenic	0.999
NPHS1	O60500-1.1	R976M	Pathogenic	0.998
NPHS1	O60500-1.1	R976N	Pathogenic	0.991
NPHS1	O60500-1.1	R976P	Pathogenic	0.998
NPHS1	O60500-1.1	R976Q	Pathogenic	0.995
NPHS1	O60500-1.1	R976S	Pathogenic	0.997
NPHS1	O60500-1.1	R976T	Pathogenic	0.997
NPHS1	O60500-1.1	R976V	Pathogenic	0.998
NPHS1	O60500-1.1	R976W	Pathogenic	0.999
NPHS1	O60500-1.1	R976Y	Pathogenic	0.994
NPHS1	O60500-1.1	Y977A	Pathogenic	0.998
NPHS1	O60500-1.1	Y977C	Pathogenic	0.994
NPHS1	O60500-1.1	Y977D	Pathogenic	0.999
NPHS1	O60500-1.1	Y977E	Pathogenic	0.999
NPHS1	O60500-1.1	Y977F	Pathogenic	0.999
NPHS1	O60500-1.1	Y977G	Pathogenic	0.999
NPHS1	O60500-1.1	Y977H	Pathogenic	0.999
NPHS1	O60500-1.1	Y977I	Pathogenic	0.997
NPHS1	O60500-1.1	Y977K	Pathogenic	0.999
NPHS1	O60500-1.1	Y977L	Pathogenic	0.997
NPHS1	O60500-1.1	Y977M	Pathogenic	0.993
NPHS1	O60500-1.1	Y977N	Pathogenic	0.999
NPHS1	O60500-1.1	Y977P	Pathogenic	0.993
NPHS1	O60500-1.1	Y977Q	Pathogenic	0.999
NPHS1	O60500-1.1	Y977R	Pathogenic	0.999
NPHS1	O60500-1.1	Y977S	Pathogenic	0.999
NPHS1	O60500-1.1	Y977T	Pathogenic	0.997
NPHS1	O60500-1.1	Y977V	Pathogenic	0.996
NPHS1	O60500-1.1	Y977W	Pathogenic	1.0
NPHS1	O60500-1.1	E978A	Neutral	0.373
NPHS1	O60500-1.1	E978C	Neutral	0.238
NPHS1	O60500-1.1	E978D	Neutral	0.25
NPHS1	O60500-1.1	E978F	Pathogenic	0.624
NPHS1	O60500-1.1	E978G	Neutral	0.283
NPHS1	O60500-1.1	E978H	Neutral	0.238
NPHS1	O60500-1.1	E978I	Pathogenic	0.566
NPHS1	O60500-1.1	E978K	Neutral	0.272
NPHS1	O60500-1.1	E978L	Pathogenic	0.529
NPHS1	O60500-1.1	E978M	Neutral	0.454
NPHS1	O60500-1.1	E978N	Neutral	0.103
NPHS1	O60500-1.1	E978P	Neutral	0.388
NPHS1	O60500-1.1	E978Q	Neutral	0.272
NPHS1	O60500-1.1	E978R	Neutral	0.258
NPHS1	O60500-1.1	E978S	Neutral	0.315
NPHS1	O60500-1.1	E978T	Neutral	0.229
NPHS1	O60500-1.1	E978V	Neutral	0.386
NPHS1	O60500-1.1	E978W	Pathogenic	0.865
NPHS1	O60500-1.1	E978Y	Neutral	0.454
NPHS1	O60500-1.1	A979C	Neutral	0.379
NPHS1	O60500-1.1	A979D	Neutral	0.36
NPHS1	O60500-1.1	A979E	Pathogenic	0.513
NPHS1	O60500-1.1	A979F	Pathogenic	0.744
NPHS1	O60500-1.1	A979G	Neutral	0.261
NPHS1	O60500-1.1	A979H	Neutral	0.218
NPHS1	O60500-1.1	A979I	Pathogenic	0.773
NPHS1	O60500-1.1	A979K	Pathogenic	0.767
NPHS1	O60500-1.1	A979L	Pathogenic	0.745
NPHS1	O60500-1.1	A979M	Pathogenic	0.593
NPHS1	O60500-1.1	A979N	Neutral	0.33
NPHS1	O60500-1.1	A979P	Neutral	0.233
NPHS1	O60500-1.1	A979Q	Neutral	0.389
NPHS1	O60500-1.1	A979R	Pathogenic	0.821
NPHS1	O60500-1.1	A979S	Neutral	0.291
NPHS1	O60500-1.1	A979T	Neutral	0.222
NPHS1	O60500-1.1	A979V	Pathogenic	0.575
NPHS1	O60500-1.1	A979W	Pathogenic	0.882
NPHS1	O60500-1.1	A979Y	Neutral	0.493
NPHS1	O60500-1.1	L980A	Neutral	0.288
NPHS1	O60500-1.1	L980C	Neutral	0.087
NPHS1	O60500-1.1	L980D	Neutral	0.256
NPHS1	O60500-1.1	L980E	Neutral	0.216
NPHS1	O60500-1.1	L980F	Neutral	0.028
NPHS1	O60500-1.1	L980G	Neutral	0.232
NPHS1	O60500-1.1	L980H	Neutral	0.066
NPHS1	O60500-1.1	L980I	Neutral	0.049
NPHS1	O60500-1.1	L980K	Neutral	0.387
NPHS1	O60500-1.1	L980M	Neutral	0.081
NPHS1	O60500-1.1	L980N	Neutral	0.262
NPHS1	O60500-1.1	L980P	Neutral	0.054
NPHS1	O60500-1.1	L980Q	Neutral	0.164
NPHS1	O60500-1.1	L980R	Neutral	0.467
NPHS1	O60500-1.1	L980S	Neutral	0.282
NPHS1	O60500-1.1	L980T	Neutral	0.191
NPHS1	O60500-1.1	L980V	Neutral	0.087
NPHS1	O60500-1.1	L980W	Neutral	0.048
NPHS1	O60500-1.1	L980Y	Neutral	0.056
NPHS1	O60500-1.1	G981A	Neutral	0.085
NPHS1	O60500-1.1	G981C	Neutral	0.107
NPHS1	O60500-1.1	G981D	Neutral	0.179
NPHS1	O60500-1.1	G981E	Neutral	0.155
NPHS1	O60500-1.1	G981F	Pathogenic	0.558
NPHS1	O60500-1.1	G981H	Neutral	0.097
NPHS1	O60500-1.1	G981I	Neutral	0.4
NPHS1	O60500-1.1	G981K	Neutral	0.364
NPHS1	O60500-1.1	G981L	Neutral	0.364
NPHS1	O60500-1.1	G981M	Neutral	0.298
NPHS1	O60500-1.1	G981N	Neutral	0.221
NPHS1	O60500-1.1	G981P	Neutral	0.117
NPHS1	O60500-1.1	G981Q	Neutral	0.1
NPHS1	O60500-1.1	G981R	Neutral	0.443
NPHS1	O60500-1.1	G981S	Neutral	0.067
NPHS1	O60500-1.1	G981T	Neutral	0.067
NPHS1	O60500-1.1	G981V	Neutral	0.209
NPHS1	O60500-1.1	G981W	Pathogenic	0.879
NPHS1	O60500-1.1	G981Y	Neutral	0.297
NPHS1	O60500-1.1	T982A	Neutral	0.051
NPHS1	O60500-1.1	T982C	Neutral	0.06
NPHS1	O60500-1.1	T982D	Neutral	0.081
NPHS1	O60500-1.1	T982E	Neutral	0.091
NPHS1	O60500-1.1	T982F	Neutral	0.244
NPHS1	O60500-1.1	T982G	Neutral	0.049
NPHS1	O60500-1.1	T982H	Neutral	0.026
NPHS1	O60500-1.1	T982I	Neutral	0.275
NPHS1	O60500-1.1	T982K	Neutral	0.239
NPHS1	O60500-1.1	T982L	Neutral	0.245
NPHS1	O60500-1.1	T982M	Neutral	0.139
NPHS1	O60500-1.1	T982N	Neutral	0.095
NPHS1	O60500-1.1	T982P	Neutral	0.037
NPHS1	O60500-1.1	T982Q	Neutral	0.057
NPHS1	O60500-1.1	T982R	Neutral	0.304
NPHS1	O60500-1.1	T982S	Neutral	0.091
NPHS1	O60500-1.1	T982V	Neutral	0.131
NPHS1	O60500-1.1	T982W	Pathogenic	0.554
NPHS1	O60500-1.1	T982Y	Neutral	0.098
NPHS1	O60500-1.1	P983A	Neutral	0.446
NPHS1	O60500-1.1	P983C	Neutral	0.157
NPHS1	O60500-1.1	P983D	Pathogenic	0.704
NPHS1	O60500-1.1	P983E	Pathogenic	0.749
NPHS1	O60500-1.1	P983F	Pathogenic	0.521
NPHS1	O60500-1.1	P983G	Pathogenic	0.572
NPHS1	O60500-1.1	P983H	Neutral	0.441
NPHS1	O60500-1.1	P983I	Pathogenic	0.561
NPHS1	O60500-1.1	P983K	Pathogenic	0.903
NPHS1	O60500-1.1	P983L	Pathogenic	0.524
NPHS1	O60500-1.1	P983M	Neutral	0.449
NPHS1	O60500-1.1	P983N	Pathogenic	0.583
NPHS1	O60500-1.1	P983Q	Pathogenic	0.644
NPHS1	O60500-1.1	P983R	Pathogenic	0.897
NPHS1	O60500-1.1	P983S	Pathogenic	0.538
NPHS1	O60500-1.1	P983T	Neutral	0.351
NPHS1	O60500-1.1	P983V	Neutral	0.337
NPHS1	O60500-1.1	P983W	Pathogenic	0.808
NPHS1	O60500-1.1	P983Y	Neutral	0.353
NPHS1	O60500-1.1	G984A	Pathogenic	0.58
NPHS1	O60500-1.1	G984C	Pathogenic	0.64
NPHS1	O60500-1.1	G984D	Pathogenic	0.765
NPHS1	O60500-1.1	G984E	Pathogenic	0.732
NPHS1	O60500-1.1	G984F	Pathogenic	0.95
NPHS1	O60500-1.1	G984H	Pathogenic	0.615
NPHS1	O60500-1.1	G984I	Pathogenic	0.909
NPHS1	O60500-1.1	G984K	Pathogenic	0.895
NPHS1	O60500-1.1	G984L	Pathogenic	0.895
NPHS1	O60500-1.1	G984M	Pathogenic	0.864
NPHS1	O60500-1.1	G984N	Pathogenic	0.809
NPHS1	O60500-1.1	G984P	Pathogenic	0.663
NPHS1	O60500-1.1	G984Q	Pathogenic	0.623
NPHS1	O60500-1.1	G984R	Pathogenic	0.922
NPHS1	O60500-1.1	G984S	Pathogenic	0.515
NPHS1	O60500-1.1	G984T	Pathogenic	0.515
NPHS1	O60500-1.1	G984V	Pathogenic	0.798
NPHS1	O60500-1.1	G984W	Pathogenic	0.991
NPHS1	O60500-1.1	G984Y	Pathogenic	0.863
NPHS1	O60500-1.1	F985A	Pathogenic	0.962
NPHS1	O60500-1.1	F985C	Pathogenic	0.857
NPHS1	O60500-1.1	F985D	Pathogenic	0.98
NPHS1	O60500-1.1	F985E	Pathogenic	0.963
NPHS1	O60500-1.1	F985G	Pathogenic	0.977
NPHS1	O60500-1.1	F985H	Pathogenic	0.937
NPHS1	O60500-1.1	F985I	Pathogenic	0.625
NPHS1	O60500-1.1	F985K	Pathogenic	0.96
NPHS1	O60500-1.1	F985L	Pathogenic	0.65
NPHS1	O60500-1.1	F985M	Pathogenic	0.789
NPHS1	O60500-1.1	F985N	Pathogenic	0.971
NPHS1	O60500-1.1	F985P	Pathogenic	0.784
NPHS1	O60500-1.1	F985Q	Pathogenic	0.925
NPHS1	O60500-1.1	F985R	Pathogenic	0.971
NPHS1	O60500-1.1	F985S	Pathogenic	0.974
NPHS1	O60500-1.1	F985T	Pathogenic	0.937
NPHS1	O60500-1.1	F985V	Pathogenic	0.801
NPHS1	O60500-1.1	F985W	Pathogenic	0.879
NPHS1	O60500-1.1	F985Y	Pathogenic	0.943
NPHS1	O60500-1.1	H986A	Neutral	0.102
NPHS1	O60500-1.1	H986C	Neutral	0.117
NPHS1	O60500-1.1	H986D	Neutral	0.22
NPHS1	O60500-1.1	H986E	Neutral	0.184
NPHS1	O60500-1.1	H986F	Neutral	0.406
NPHS1	O60500-1.1	H986G	Neutral	0.142
NPHS1	O60500-1.1	H986I	Neutral	0.195
NPHS1	O60500-1.1	H986K	Neutral	0.236
NPHS1	O60500-1.1	H986L	Neutral	0.172
NPHS1	O60500-1.1	H986M	Neutral	0.134
NPHS1	O60500-1.1	H986N	Neutral	0.302
NPHS1	O60500-1.1	H986P	Neutral	0.108
NPHS1	O60500-1.1	H986Q	Neutral	0.097
NPHS1	O60500-1.1	H986R	Neutral	0.39
NPHS1	O60500-1.1	H986S	Neutral	0.126
NPHS1	O60500-1.1	H986T	Neutral	0.054
NPHS1	O60500-1.1	H986V	Neutral	0.107
NPHS1	O60500-1.1	H986W	Pathogenic	0.639
NPHS1	O60500-1.1	H986Y	Neutral	0.433
NPHS1	O60500-1.1	Y987A	Pathogenic	0.997
NPHS1	O60500-1.1	Y987C	Pathogenic	0.988
NPHS1	O60500-1.1	Y987D	Pathogenic	0.998
NPHS1	O60500-1.1	Y987E	Pathogenic	0.998
NPHS1	O60500-1.1	Y987F	Pathogenic	0.998
NPHS1	O60500-1.1	Y987G	Pathogenic	0.998
NPHS1	O60500-1.1	Y987H	Pathogenic	0.998
NPHS1	O60500-1.1	Y987I	Pathogenic	0.994
NPHS1	O60500-1.1	Y987K	Pathogenic	0.998
NPHS1	O60500-1.1	Y987L	Pathogenic	0.993
NPHS1	O60500-1.1	Y987M	Pathogenic	0.987
NPHS1	O60500-1.1	Y987N	Pathogenic	0.999
NPHS1	O60500-1.1	Y987P	Pathogenic	0.986
NPHS1	O60500-1.1	Y987Q	Pathogenic	0.997
NPHS1	O60500-1.1	Y987R	Pathogenic	0.998
NPHS1	O60500-1.1	Y987S	Pathogenic	0.998
NPHS1	O60500-1.1	Y987T	Pathogenic	0.995
NPHS1	O60500-1.1	Y987V	Pathogenic	0.991
NPHS1	O60500-1.1	Y987W	Pathogenic	0.999
NPHS1	O60500-1.1	V988A	Neutral	0.38
NPHS1	O60500-1.1	V988C	Neutral	0.088
NPHS1	O60500-1.1	V988D	Neutral	0.343
NPHS1	O60500-1.1	V988E	Neutral	0.335
NPHS1	O60500-1.1	V988F	Neutral	0.171
NPHS1	O60500-1.1	V988G	Neutral	0.314
NPHS1	O60500-1.1	V988H	Neutral	0.117
NPHS1	O60500-1.1	V988I	Neutral	0.445
NPHS1	O60500-1.1	V988K	Pathogenic	0.611
NPHS1	O60500-1.1	V988L	Neutral	0.237
NPHS1	O60500-1.1	V988M	Neutral	0.134
NPHS1	O60500-1.1	V988N	Neutral	0.265
NPHS1	O60500-1.1	V988P	Neutral	0.08
NPHS1	O60500-1.1	V988Q	Neutral	0.234
NPHS1	O60500-1.1	V988R	Pathogenic	0.595
NPHS1	O60500-1.1	V988S	Neutral	0.285
NPHS1	O60500-1.1	V988T	Neutral	0.264
NPHS1	O60500-1.1	V988W	Neutral	0.263
NPHS1	O60500-1.1	V988Y	Neutral	0.129
NPHS1	O60500-1.1	D989A	Pathogenic	0.984
NPHS1	O60500-1.1	D989C	Pathogenic	0.986
NPHS1	O60500-1.1	D989E	Pathogenic	0.985
NPHS1	O60500-1.1	D989F	Pathogenic	0.998
NPHS1	O60500-1.1	D989G	Pathogenic	0.989
NPHS1	O60500-1.1	D989H	Pathogenic	0.987
NPHS1	O60500-1.1	D989I	Pathogenic	0.998
NPHS1	O60500-1.1	D989K	Pathogenic	0.976
NPHS1	O60500-1.1	D989L	Pathogenic	0.996
NPHS1	O60500-1.1	D989M	Pathogenic	0.995
NPHS1	O60500-1.1	D989N	Pathogenic	0.971
NPHS1	O60500-1.1	D989P	Pathogenic	0.99
NPHS1	O60500-1.1	D989Q	Pathogenic	0.984
NPHS1	O60500-1.1	D989R	Pathogenic	0.974
NPHS1	O60500-1.1	D989S	Pathogenic	0.986
NPHS1	O60500-1.1	D989T	Pathogenic	0.98
NPHS1	O60500-1.1	D989V	Pathogenic	0.992
NPHS1	O60500-1.1	D989W	Pathogenic	0.999
NPHS1	O60500-1.1	D989Y	Pathogenic	0.995
NPHS1	O60500-1.1	V990A	Pathogenic	0.986
NPHS1	O60500-1.1	V990C	Pathogenic	0.917
NPHS1	O60500-1.1	V990D	Pathogenic	0.984
NPHS1	O60500-1.1	V990E	Pathogenic	0.983
NPHS1	O60500-1.1	V990F	Pathogenic	0.96
NPHS1	O60500-1.1	V990G	Pathogenic	0.981
NPHS1	O60500-1.1	V990H	Pathogenic	0.939
NPHS1	O60500-1.1	V990I	Pathogenic	0.989
NPHS1	O60500-1.1	V990K	Pathogenic	0.995
NPHS1	O60500-1.1	V990L	Pathogenic	0.973
NPHS1	O60500-1.1	V990M	Pathogenic	0.947
NPHS1	O60500-1.1	V990N	Pathogenic	0.976
NPHS1	O60500-1.1	V990P	Pathogenic	0.909
NPHS1	O60500-1.1	V990Q	Pathogenic	0.972
NPHS1	O60500-1.1	V990R	Pathogenic	0.994
NPHS1	O60500-1.1	V990S	Pathogenic	0.979
NPHS1	O60500-1.1	V990T	Pathogenic	0.976
NPHS1	O60500-1.1	V990W	Pathogenic	0.976
NPHS1	O60500-1.1	V990Y	Pathogenic	0.945
NPHS1	O60500-1.1	V991A	Neutral	0.006
NPHS1	O60500-1.1	V991C	Neutral	0.001
NPHS1	O60500-1.1	V991D	Neutral	0.006
NPHS1	O60500-1.1	V991E	Neutral	0.005
NPHS1	O60500-1.1	V991F	Neutral	0.002
NPHS1	O60500-1.1	V991G	Neutral	0.005
NPHS1	O60500-1.1	V991H	Neutral	0.001
NPHS1	O60500-1.1	V991I	Neutral	0.008
NPHS1	O60500-1.1	V991K	Neutral	0.016
NPHS1	O60500-1.1	V991L	Neutral	0.003
NPHS1	O60500-1.1	V991M	Neutral	0.002
NPHS1	O60500-1.1	V991N	Neutral	0.004
NPHS1	O60500-1.1	V991P	Neutral	0.001
NPHS1	O60500-1.1	V991Q	Neutral	0.003
NPHS1	O60500-1.1	V991R	Neutral	0.015
NPHS1	O60500-1.1	V991S	Neutral	0.004
NPHS1	O60500-1.1	V991T	Neutral	0.004
NPHS1	O60500-1.1	V991W	Neutral	0.004
NPHS1	O60500-1.1	V991Y	Neutral	0.002
NPHS1	O60500-1.1	P992A	Pathogenic	0.946
NPHS1	O60500-1.1	P992C	Pathogenic	0.801
NPHS1	O60500-1.1	P992D	Pathogenic	0.981
NPHS1	O60500-1.1	P992E	Pathogenic	0.985
NPHS1	O60500-1.1	P992F	Pathogenic	0.959
NPHS1	O60500-1.1	P992G	Pathogenic	0.967
NPHS1	O60500-1.1	P992H	Pathogenic	0.945
NPHS1	O60500-1.1	P992I	Pathogenic	0.965
NPHS1	O60500-1.1	P992K	Pathogenic	0.995
NPHS1	O60500-1.1	P992L	Pathogenic	0.96
NPHS1	O60500-1.1	P992M	Pathogenic	0.946
NPHS1	O60500-1.1	P992N	Pathogenic	0.968
NPHS1	O60500-1.1	P992Q	Pathogenic	0.975
NPHS1	O60500-1.1	P992R	Pathogenic	0.995
NPHS1	O60500-1.1	P992S	Pathogenic	0.962
NPHS1	O60500-1.1	P992T	Pathogenic	0.921
NPHS1	O60500-1.1	P992V	Pathogenic	0.917
NPHS1	O60500-1.1	P992W	Pathogenic	0.989
NPHS1	O60500-1.1	P992Y	Pathogenic	0.922
NPHS1	O60500-1.1	P993A	Neutral	0.376
NPHS1	O60500-1.1	P993C	Neutral	0.122
NPHS1	O60500-1.1	P993D	Pathogenic	0.641
NPHS1	O60500-1.1	P993E	Pathogenic	0.691
NPHS1	O60500-1.1	P993F	Neutral	0.449
NPHS1	O60500-1.1	P993G	Pathogenic	0.5
NPHS1	O60500-1.1	P993H	Neutral	0.371
NPHS1	O60500-1.1	P993I	Neutral	0.49
NPHS1	O60500-1.1	P993K	Pathogenic	0.875
NPHS1	O60500-1.1	P993L	Neutral	0.451
NPHS1	O60500-1.1	P993M	Neutral	0.379
NPHS1	O60500-1.1	P993N	Pathogenic	0.511
NPHS1	O60500-1.1	P993Q	Pathogenic	0.575
NPHS1	O60500-1.1	P993R	Pathogenic	0.867
NPHS1	O60500-1.1	P993S	Neutral	0.466
NPHS1	O60500-1.1	P993T	Neutral	0.289
NPHS1	O60500-1.1	P993V	Neutral	0.276
NPHS1	O60500-1.1	P993W	Pathogenic	0.759
NPHS1	O60500-1.1	P993Y	Neutral	0.29
NPHS1	O60500-1.1	Q994A	Neutral	0.354
NPHS1	O60500-1.1	Q994C	Neutral	0.3
NPHS1	O60500-1.1	Q994D	Neutral	0.323
NPHS1	O60500-1.1	Q994E	Neutral	0.363
NPHS1	O60500-1.1	Q994F	Pathogenic	0.547
NPHS1	O60500-1.1	Q994G	Neutral	0.266
NPHS1	O60500-1.1	Q994H	Neutral	0.185
NPHS1	O60500-1.1	Q994I	Neutral	0.487
NPHS1	O60500-1.1	Q994K	Neutral	0.485
NPHS1	O60500-1.1	Q994L	Pathogenic	0.549
NPHS1	O60500-1.1	Q994M	Pathogenic	0.574
NPHS1	O60500-1.1	Q994N	Neutral	0.248
NPHS1	O60500-1.1	Q994P	Neutral	0.369
NPHS1	O60500-1.1	Q994R	Pathogenic	0.567
NPHS1	O60500-1.1	Q994S	Neutral	0.298
NPHS1	O60500-1.1	Q994T	Neutral	0.215
NPHS1	O60500-1.1	Q994V	Neutral	0.366
NPHS1	O60500-1.1	Q994W	Pathogenic	0.874
NPHS1	O60500-1.1	Q994Y	Neutral	0.474
NPHS1	O60500-1.1	A995C	Pathogenic	0.519
NPHS1	O60500-1.1	A995D	Neutral	0.499
NPHS1	O60500-1.1	A995E	Pathogenic	0.651
NPHS1	O60500-1.1	A995F	Pathogenic	0.837
NPHS1	O60500-1.1	A995G	Neutral	0.385
NPHS1	O60500-1.1	A995H	Neutral	0.33
NPHS1	O60500-1.1	A995I	Pathogenic	0.858
NPHS1	O60500-1.1	A995K	Pathogenic	0.853
NPHS1	O60500-1.1	A995L	Pathogenic	0.838
NPHS1	O60500-1.1	A995M	Pathogenic	0.72
NPHS1	O60500-1.1	A995N	Neutral	0.465
NPHS1	O60500-1.1	A995P	Neutral	0.349
NPHS1	O60500-1.1	A995Q	Pathogenic	0.53
NPHS1	O60500-1.1	A995R	Pathogenic	0.89
NPHS1	O60500-1.1	A995S	Neutral	0.42
NPHS1	O60500-1.1	A995T	Neutral	0.335
NPHS1	O60500-1.1	A995V	Pathogenic	0.705
NPHS1	O60500-1.1	A995W	Pathogenic	0.93
NPHS1	O60500-1.1	A995Y	Pathogenic	0.632
NPHS1	O60500-1.1	T996A	Neutral	0.424
NPHS1	O60500-1.1	T996C	Neutral	0.463
NPHS1	O60500-1.1	T996D	Pathogenic	0.545
NPHS1	O60500-1.1	T996E	Pathogenic	0.578
NPHS1	O60500-1.1	T996F	Pathogenic	0.814
NPHS1	O60500-1.1	T996G	Neutral	0.413
NPHS1	O60500-1.1	T996H	Neutral	0.265
NPHS1	O60500-1.1	T996I	Pathogenic	0.837
NPHS1	O60500-1.1	T996K	Pathogenic	0.81
NPHS1	O60500-1.1	T996L	Pathogenic	0.816
NPHS1	O60500-1.1	T996M	Pathogenic	0.687
NPHS1	O60500-1.1	T996N	Pathogenic	0.587
NPHS1	O60500-1.1	T996P	Neutral	0.346
NPHS1	O60500-1.1	T996Q	Neutral	0.453
NPHS1	O60500-1.1	T996R	Pathogenic	0.856
NPHS1	O60500-1.1	T996S	Pathogenic	0.578
NPHS1	O60500-1.1	T996V	Pathogenic	0.672
NPHS1	O60500-1.1	T996W	Pathogenic	0.944
NPHS1	O60500-1.1	T996Y	Pathogenic	0.595
NPHS1	O60500-1.1	T997A	Neutral	0.101
NPHS1	O60500-1.1	T997C	Neutral	0.116
NPHS1	O60500-1.1	T997D	Neutral	0.154
NPHS1	O60500-1.1	T997E	Neutral	0.172
NPHS1	O60500-1.1	T997F	Neutral	0.4
NPHS1	O60500-1.1	T997G	Neutral	0.097
NPHS1	O60500-1.1	T997H	Neutral	0.052
NPHS1	O60500-1.1	T997I	Neutral	0.439
NPHS1	O60500-1.1	T997K	Neutral	0.394
NPHS1	O60500-1.1	T997L	Neutral	0.402
NPHS1	O60500-1.1	T997M	Neutral	0.251
NPHS1	O60500-1.1	T997N	Neutral	0.178
NPHS1	O60500-1.1	T997P	Neutral	0.074
NPHS1	O60500-1.1	T997Q	Neutral	0.112
NPHS1	O60500-1.1	T997R	Neutral	0.474
NPHS1	O60500-1.1	T997S	Neutral	0.172
NPHS1	O60500-1.1	T997V	Neutral	0.238
NPHS1	O60500-1.1	T997W	Pathogenic	0.72
NPHS1	O60500-1.1	T997Y	Neutral	0.183
NPHS1	O60500-1.1	F998A	Pathogenic	0.999
NPHS1	O60500-1.1	F998C	Pathogenic	0.997
NPHS1	O60500-1.1	F998D	Pathogenic	1.0
NPHS1	O60500-1.1	F998E	Pathogenic	0.999
NPHS1	O60500-1.1	F998G	Pathogenic	1.0
NPHS1	O60500-1.1	F998H	Pathogenic	0.999
NPHS1	O60500-1.1	F998I	Pathogenic	0.988
NPHS1	O60500-1.1	F998K	Pathogenic	0.999
NPHS1	O60500-1.1	F998L	Pathogenic	0.989
NPHS1	O60500-1.1	F998M	Pathogenic	0.995
NPHS1	O60500-1.1	F998N	Pathogenic	0.999
NPHS1	O60500-1.1	F998P	Pathogenic	0.994
NPHS1	O60500-1.1	F998Q	Pathogenic	0.998
NPHS1	O60500-1.1	F998R	Pathogenic	0.999
NPHS1	O60500-1.1	F998S	Pathogenic	0.999
NPHS1	O60500-1.1	F998T	Pathogenic	0.999
NPHS1	O60500-1.1	F998V	Pathogenic	0.995
NPHS1	O60500-1.1	F998W	Pathogenic	0.997
NPHS1	O60500-1.1	F998Y	Pathogenic	0.999
NPHS1	O60500-1.1	T999A	Pathogenic	0.938
NPHS1	O60500-1.1	T999C	Pathogenic	0.946
NPHS1	O60500-1.1	T999D	Pathogenic	0.961
NPHS1	O60500-1.1	T999E	Pathogenic	0.965
NPHS1	O60500-1.1	T999F	Pathogenic	0.989
NPHS1	O60500-1.1	T999G	Pathogenic	0.935
NPHS1	O60500-1.1	T999H	Pathogenic	0.881
NPHS1	O60500-1.1	T999I	Pathogenic	0.991
NPHS1	O60500-1.1	T999K	Pathogenic	0.989
NPHS1	O60500-1.1	T999L	Pathogenic	0.989
NPHS1	O60500-1.1	T999M	Pathogenic	0.978
NPHS1	O60500-1.1	T999N	Pathogenic	0.967
NPHS1	O60500-1.1	T999P	Pathogenic	0.915
NPHS1	O60500-1.1	T999Q	Pathogenic	0.944
NPHS1	O60500-1.1	T999R	Pathogenic	0.992
NPHS1	O60500-1.1	T999S	Pathogenic	0.965
NPHS1	O60500-1.1	T999V	Pathogenic	0.977
NPHS1	O60500-1.1	T999W	Pathogenic	0.997
NPHS1	O60500-1.1	T999Y	Pathogenic	0.968
NPHS1	O60500-1.1	L1000A	Pathogenic	0.829
NPHS1	O60500-1.1	L1000C	Pathogenic	0.532
NPHS1	O60500-1.1	L1000D	Pathogenic	0.805
NPHS1	O60500-1.1	L1000E	Pathogenic	0.768
NPHS1	O60500-1.1	L1000F	Neutral	0.259
NPHS1	O60500-1.1	L1000G	Pathogenic	0.784
NPHS1	O60500-1.1	L1000H	Neutral	0.46
NPHS1	O60500-1.1	L1000I	Neutral	0.381
NPHS1	O60500-1.1	L1000K	Pathogenic	0.883
NPHS1	O60500-1.1	L1000M	Pathogenic	0.515
NPHS1	O60500-1.1	L1000N	Pathogenic	0.81
NPHS1	O60500-1.1	L1000P	Neutral	0.408
NPHS1	O60500-1.1	L1000Q	Pathogenic	0.702
NPHS1	O60500-1.1	L1000R	Pathogenic	0.913
NPHS1	O60500-1.1	L1000S	Pathogenic	0.825
NPHS1	O60500-1.1	L1000T	Pathogenic	0.739
NPHS1	O60500-1.1	L1000V	Pathogenic	0.532
NPHS1	O60500-1.1	L1000W	Neutral	0.378
NPHS1	O60500-1.1	L1000Y	Neutral	0.417
NPHS1	O60500-1.1	T1001A	Pathogenic	0.946
NPHS1	O60500-1.1	T1001C	Pathogenic	0.954
NPHS1	O60500-1.1	T1001D	Pathogenic	0.966
NPHS1	O60500-1.1	T1001E	Pathogenic	0.97
NPHS1	O60500-1.1	T1001F	Pathogenic	0.991
NPHS1	O60500-1.1	T1001G	Pathogenic	0.944
NPHS1	O60500-1.1	T1001H	Pathogenic	0.896
NPHS1	O60500-1.1	T1001I	Pathogenic	0.992
NPHS1	O60500-1.1	T1001K	Pathogenic	0.99
NPHS1	O60500-1.1	T1001L	Pathogenic	0.991
NPHS1	O60500-1.1	T1001M	Pathogenic	0.981
NPHS1	O60500-1.1	T1001N	Pathogenic	0.971
NPHS1	O60500-1.1	T1001P	Pathogenic	0.927
NPHS1	O60500-1.1	T1001Q	Pathogenic	0.952
NPHS1	O60500-1.1	T1001R	Pathogenic	0.993
NPHS1	O60500-1.1	T1001S	Pathogenic	0.97
NPHS1	O60500-1.1	T1001V	Pathogenic	0.98
NPHS1	O60500-1.1	T1001W	Pathogenic	0.998
NPHS1	O60500-1.1	T1001Y	Pathogenic	0.972
NPHS1	O60500-1.1	G1002A	Pathogenic	0.855
NPHS1	O60500-1.1	G1002C	Pathogenic	0.884
NPHS1	O60500-1.1	G1002D	Pathogenic	0.933
NPHS1	O60500-1.1	G1002E	Pathogenic	0.921
NPHS1	O60500-1.1	G1002F	Pathogenic	0.988
NPHS1	O60500-1.1	G1002H	Pathogenic	0.872
NPHS1	O60500-1.1	G1002I	Pathogenic	0.977
NPHS1	O60500-1.1	G1002K	Pathogenic	0.973
NPHS1	O60500-1.1	G1002L	Pathogenic	0.973
NPHS1	O60500-1.1	G1002M	Pathogenic	0.964
NPHS1	O60500-1.1	G1002N	Pathogenic	0.948
NPHS1	O60500-1.1	G1002P	Pathogenic	0.894
NPHS1	O60500-1.1	G1002Q	Pathogenic	0.876
NPHS1	O60500-1.1	G1002R	Pathogenic	0.981
NPHS1	O60500-1.1	G1002S	Pathogenic	0.819
NPHS1	O60500-1.1	G1002T	Pathogenic	0.819
NPHS1	O60500-1.1	G1002V	Pathogenic	0.944
NPHS1	O60500-1.1	G1002W	Pathogenic	0.998
NPHS1	O60500-1.1	G1002Y	Pathogenic	0.964
NPHS1	O60500-1.1	L1003A	Pathogenic	0.992
NPHS1	O60500-1.1	L1003C	Pathogenic	0.967
NPHS1	O60500-1.1	L1003D	Pathogenic	0.991
NPHS1	O60500-1.1	L1003E	Pathogenic	0.988
NPHS1	O60500-1.1	L1003F	Pathogenic	0.9
NPHS1	O60500-1.1	L1003G	Pathogenic	0.989
NPHS1	O60500-1.1	L1003H	Pathogenic	0.956
NPHS1	O60500-1.1	L1003I	Pathogenic	0.94
NPHS1	O60500-1.1	L1003K	Pathogenic	0.995
NPHS1	O60500-1.1	L1003M	Pathogenic	0.964
NPHS1	O60500-1.1	L1003N	Pathogenic	0.991
NPHS1	O60500-1.1	L1003P	Pathogenic	0.946
NPHS1	O60500-1.1	L1003Q	Pathogenic	0.984
NPHS1	O60500-1.1	L1003R	Pathogenic	0.996
NPHS1	O60500-1.1	L1003S	Pathogenic	0.992
NPHS1	O60500-1.1	L1003T	Pathogenic	0.986
NPHS1	O60500-1.1	L1003V	Pathogenic	0.967
NPHS1	O60500-1.1	L1003W	Pathogenic	0.94
NPHS1	O60500-1.1	L1003Y	Pathogenic	0.948
NPHS1	O60500-1.1	Q1004A	Neutral	0.189
NPHS1	O60500-1.1	Q1004C	Neutral	0.155
NPHS1	O60500-1.1	Q1004D	Neutral	0.17
NPHS1	O60500-1.1	Q1004E	Neutral	0.196
NPHS1	O60500-1.1	Q1004F	Neutral	0.34
NPHS1	O60500-1.1	Q1004G	Neutral	0.134
NPHS1	O60500-1.1	Q1004H	Neutral	0.089
NPHS1	O60500-1.1	Q1004I	Neutral	0.289
NPHS1	O60500-1.1	Q1004K	Neutral	0.287
NPHS1	O60500-1.1	Q1004L	Neutral	0.342
NPHS1	O60500-1.1	Q1004M	Neutral	0.365
NPHS1	O60500-1.1	Q1004N	Neutral	0.124
NPHS1	O60500-1.1	Q1004P	Neutral	0.2
NPHS1	O60500-1.1	Q1004R	Neutral	0.359
NPHS1	O60500-1.1	Q1004S	Neutral	0.153
NPHS1	O60500-1.1	Q1004T	Neutral	0.105
NPHS1	O60500-1.1	Q1004V	Neutral	0.198
NPHS1	O60500-1.1	Q1004W	Pathogenic	0.747
NPHS1	O60500-1.1	Q1004Y	Neutral	0.278
NPHS1	O60500-1.1	P1005A	Pathogenic	0.594
NPHS1	O60500-1.1	P1005C	Neutral	0.252
NPHS1	O60500-1.1	P1005D	Pathogenic	0.812
NPHS1	O60500-1.1	P1005E	Pathogenic	0.845
NPHS1	O60500-1.1	P1005F	Pathogenic	0.664
NPHS1	O60500-1.1	P1005G	Pathogenic	0.708
NPHS1	O60500-1.1	P1005H	Pathogenic	0.589
NPHS1	O60500-1.1	P1005I	Pathogenic	0.699
NPHS1	O60500-1.1	P1005K	Pathogenic	0.944
NPHS1	O60500-1.1	P1005L	Pathogenic	0.666
NPHS1	O60500-1.1	P1005M	Pathogenic	0.597
NPHS1	O60500-1.1	P1005N	Pathogenic	0.717
NPHS1	O60500-1.1	P1005Q	Pathogenic	0.767
NPHS1	O60500-1.1	P1005R	Pathogenic	0.941
NPHS1	O60500-1.1	P1005S	Pathogenic	0.679
NPHS1	O60500-1.1	P1005T	Neutral	0.496
NPHS1	O60500-1.1	P1005V	Neutral	0.481
NPHS1	O60500-1.1	P1005W	Pathogenic	0.884
NPHS1	O60500-1.1	P1005Y	Neutral	0.498
NPHS1	O60500-1.1	S1006A	Neutral	0.159
NPHS1	O60500-1.1	S1006C	Neutral	0.215
NPHS1	O60500-1.1	S1006D	Neutral	0.231
NPHS1	O60500-1.1	S1006E	Neutral	0.274
NPHS1	O60500-1.1	S1006F	Pathogenic	0.66
NPHS1	O60500-1.1	S1006G	Neutral	0.112
NPHS1	O60500-1.1	S1006H	Neutral	0.141
NPHS1	O60500-1.1	S1006I	Pathogenic	0.604
NPHS1	O60500-1.1	S1006K	Pathogenic	0.541
NPHS1	O60500-1.1	S1006L	Pathogenic	0.567
NPHS1	O60500-1.1	S1006M	Neutral	0.493
NPHS1	O60500-1.1	S1006N	Neutral	0.281
NPHS1	O60500-1.1	S1006P	Neutral	0.169
NPHS1	O60500-1.1	S1006Q	Neutral	0.186
NPHS1	O60500-1.1	S1006R	Pathogenic	0.523
NPHS1	O60500-1.1	S1006T	Neutral	0.196
NPHS1	O60500-1.1	S1006V	Neutral	0.289
NPHS1	O60500-1.1	S1006W	Pathogenic	0.834
NPHS1	O60500-1.1	S1006Y	Neutral	0.394
NPHS1	O60500-1.1	T1007A	Pathogenic	0.924
NPHS1	O60500-1.1	T1007C	Pathogenic	0.935
NPHS1	O60500-1.1	T1007D	Pathogenic	0.952
NPHS1	O60500-1.1	T1007E	Pathogenic	0.958
NPHS1	O60500-1.1	T1007F	Pathogenic	0.986
NPHS1	O60500-1.1	T1007G	Pathogenic	0.921
NPHS1	O60500-1.1	T1007H	Pathogenic	0.857
NPHS1	O60500-1.1	T1007I	Pathogenic	0.988
NPHS1	O60500-1.1	T1007K	Pathogenic	0.986
NPHS1	O60500-1.1	T1007L	Pathogenic	0.987
NPHS1	O60500-1.1	T1007M	Pathogenic	0.973
NPHS1	O60500-1.1	T1007N	Pathogenic	0.959
NPHS1	O60500-1.1	T1007P	Pathogenic	0.898
NPHS1	O60500-1.1	T1007Q	Pathogenic	0.932
NPHS1	O60500-1.1	T1007R	Pathogenic	0.99
NPHS1	O60500-1.1	T1007S	Pathogenic	0.958
NPHS1	O60500-1.1	T1007V	Pathogenic	0.971
NPHS1	O60500-1.1	T1007W	Pathogenic	0.996
NPHS1	O60500-1.1	T1007Y	Pathogenic	0.961
NPHS1	O60500-1.1	R1008A	Pathogenic	0.639
NPHS1	O60500-1.1	R1008C	Pathogenic	0.581
NPHS1	O60500-1.1	R1008D	Neutral	0.119
NPHS1	O60500-1.1	R1008E	Neutral	0.193
NPHS1	O60500-1.1	R1008F	Pathogenic	0.591
NPHS1	O60500-1.1	R1008G	Pathogenic	0.541
NPHS1	O60500-1.1	R1008H	Neutral	0.379
NPHS1	O60500-1.1	R1008I	Pathogenic	0.657
NPHS1	O60500-1.1	R1008K	Neutral	0.146
NPHS1	O60500-1.1	R1008L	Pathogenic	0.711
NPHS1	O60500-1.1	R1008M	Pathogenic	0.646
NPHS1	O60500-1.1	R1008N	Neutral	0.256
NPHS1	O60500-1.1	R1008P	Pathogenic	0.56
NPHS1	O60500-1.1	R1008Q	Neutral	0.372
NPHS1	O60500-1.1	R1008S	Neutral	0.479
NPHS1	O60500-1.1	R1008T	Neutral	0.47
NPHS1	O60500-1.1	R1008V	Pathogenic	0.557
NPHS1	O60500-1.1	R1008W	Pathogenic	0.751
NPHS1	O60500-1.1	R1008Y	Neutral	0.353
NPHS1	O60500-1.1	Y1009A	Pathogenic	0.998
NPHS1	O60500-1.1	Y1009C	Pathogenic	0.993
NPHS1	O60500-1.1	Y1009D	Pathogenic	0.999
NPHS1	O60500-1.1	Y1009E	Pathogenic	0.999
NPHS1	O60500-1.1	Y1009F	Pathogenic	0.999
NPHS1	O60500-1.1	Y1009G	Pathogenic	0.999
NPHS1	O60500-1.1	Y1009H	Pathogenic	0.999
NPHS1	O60500-1.1	Y1009I	Pathogenic	0.997
NPHS1	O60500-1.1	Y1009K	Pathogenic	0.999
NPHS1	O60500-1.1	Y1009L	Pathogenic	0.996
NPHS1	O60500-1.1	Y1009M	Pathogenic	0.993
NPHS1	O60500-1.1	Y1009N	Pathogenic	0.999
NPHS1	O60500-1.1	Y1009P	Pathogenic	0.992
NPHS1	O60500-1.1	Y1009Q	Pathogenic	0.998
NPHS1	O60500-1.1	Y1009R	Pathogenic	0.999
NPHS1	O60500-1.1	Y1009S	Pathogenic	0.999
NPHS1	O60500-1.1	Y1009T	Pathogenic	0.997
NPHS1	O60500-1.1	Y1009V	Pathogenic	0.995
NPHS1	O60500-1.1	Y1009W	Pathogenic	1.0
NPHS1	O60500-1.1	R1010A	Neutral	0.418
NPHS1	O60500-1.1	R1010C	Neutral	0.36
NPHS1	O60500-1.1	R1010D	Neutral	0.052
NPHS1	O60500-1.1	R1010E	Neutral	0.088
NPHS1	O60500-1.1	R1010F	Neutral	0.369
NPHS1	O60500-1.1	R1010G	Neutral	0.323
NPHS1	O60500-1.1	R1010H	Neutral	0.198
NPHS1	O60500-1.1	R1010I	Neutral	0.437
NPHS1	O60500-1.1	R1010K	Neutral	0.065
NPHS1	O60500-1.1	R1010L	Neutral	0.499
NPHS1	O60500-1.1	R1010M	Neutral	0.424
NPHS1	O60500-1.1	R1010N	Neutral	0.122
NPHS1	O60500-1.1	R1010P	Neutral	0.34
NPHS1	O60500-1.1	R1010Q	Neutral	0.193
NPHS1	O60500-1.1	R1010S	Neutral	0.272
NPHS1	O60500-1.1	R1010T	Neutral	0.264
NPHS1	O60500-1.1	R1010V	Neutral	0.337
NPHS1	O60500-1.1	R1010W	Pathogenic	0.55
NPHS1	O60500-1.1	R1010Y	Neutral	0.181
NPHS1	O60500-1.1	V1011A	Neutral	0.2
NPHS1	O60500-1.1	V1011C	Neutral	0.038
NPHS1	O60500-1.1	V1011D	Neutral	0.175
NPHS1	O60500-1.1	V1011E	Neutral	0.17
NPHS1	O60500-1.1	V1011F	Neutral	0.077
NPHS1	O60500-1.1	V1011G	Neutral	0.157
NPHS1	O60500-1.1	V1011H	Neutral	0.051
NPHS1	O60500-1.1	V1011I	Neutral	0.246
NPHS1	O60500-1.1	V1011K	Neutral	0.39
NPHS1	O60500-1.1	V1011L	Neutral	0.112
NPHS1	O60500-1.1	V1011M	Neutral	0.059
NPHS1	O60500-1.1	V1011N	Neutral	0.128
NPHS1	O60500-1.1	V1011P	Neutral	0.034
NPHS1	O60500-1.1	V1011Q	Neutral	0.11
NPHS1	O60500-1.1	V1011R	Neutral	0.374
NPHS1	O60500-1.1	V1011S	Neutral	0.14
NPHS1	O60500-1.1	V1011T	Neutral	0.127
NPHS1	O60500-1.1	V1011W	Neutral	0.127
NPHS1	O60500-1.1	V1011Y	Neutral	0.057
NPHS1	O60500-1.1	W1012A	Pathogenic	0.989
NPHS1	O60500-1.1	W1012C	Pathogenic	0.97
NPHS1	O60500-1.1	W1012D	Pathogenic	0.994
NPHS1	O60500-1.1	W1012E	Pathogenic	0.993
NPHS1	O60500-1.1	W1012F	Pathogenic	0.911
NPHS1	O60500-1.1	W1012G	Pathogenic	0.997
NPHS1	O60500-1.1	W1012H	Pathogenic	0.982
NPHS1	O60500-1.1	W1012I	Pathogenic	0.725
NPHS1	O60500-1.1	W1012K	Pathogenic	0.992
NPHS1	O60500-1.1	W1012L	Pathogenic	0.821
NPHS1	O60500-1.1	W1012M	Pathogenic	0.932
NPHS1	O60500-1.1	W1012N	Pathogenic	0.992
NPHS1	O60500-1.1	W1012P	Pathogenic	0.952
NPHS1	O60500-1.1	W1012Q	Pathogenic	0.99
NPHS1	O60500-1.1	W1012R	Pathogenic	0.99
NPHS1	O60500-1.1	W1012S	Pathogenic	0.993
NPHS1	O60500-1.1	W1012T	Pathogenic	0.988
NPHS1	O60500-1.1	W1012V	Pathogenic	0.908
NPHS1	O60500-1.1	W1012Y	Pathogenic	0.979
NPHS1	O60500-1.1	L1013A	Pathogenic	0.841
NPHS1	O60500-1.1	L1013C	Pathogenic	0.554
NPHS1	O60500-1.1	L1013D	Pathogenic	0.819
NPHS1	O60500-1.1	L1013E	Pathogenic	0.783
NPHS1	O60500-1.1	L1013F	Neutral	0.277
NPHS1	O60500-1.1	L1013G	Pathogenic	0.799
NPHS1	O60500-1.1	L1013H	Neutral	0.482
NPHS1	O60500-1.1	L1013I	Neutral	0.402
NPHS1	O60500-1.1	L1013K	Pathogenic	0.892
NPHS1	O60500-1.1	L1013M	Pathogenic	0.537
NPHS1	O60500-1.1	L1013N	Pathogenic	0.823
NPHS1	O60500-1.1	L1013P	Neutral	0.429
NPHS1	O60500-1.1	L1013Q	Pathogenic	0.72
NPHS1	O60500-1.1	L1013R	Pathogenic	0.92
NPHS1	O60500-1.1	L1013S	Pathogenic	0.838
NPHS1	O60500-1.1	L1013T	Pathogenic	0.756
NPHS1	O60500-1.1	L1013V	Pathogenic	0.554
NPHS1	O60500-1.1	L1013W	Neutral	0.399
NPHS1	O60500-1.1	L1013Y	Neutral	0.439
NPHS1	O60500-1.1	L1014A	Pathogenic	0.618
NPHS1	O60500-1.1	L1014C	Neutral	0.274
NPHS1	O60500-1.1	L1014D	Pathogenic	0.579
NPHS1	O60500-1.1	L1014E	Pathogenic	0.524
NPHS1	O60500-1.1	L1014F	Neutral	0.104
NPHS1	O60500-1.1	L1014G	Pathogenic	0.547
NPHS1	O60500-1.1	L1014H	Neutral	0.22
NPHS1	O60500-1.1	L1014I	Neutral	0.17
NPHS1	O60500-1.1	L1014K	Pathogenic	0.716
NPHS1	O60500-1.1	L1014M	Neutral	0.261
NPHS1	O60500-1.1	L1014N	Pathogenic	0.586
NPHS1	O60500-1.1	L1014P	Neutral	0.186
NPHS1	O60500-1.1	L1014Q	Neutral	0.439
NPHS1	O60500-1.1	L1014R	Pathogenic	0.778
NPHS1	O60500-1.1	L1014S	Pathogenic	0.611
NPHS1	O60500-1.1	L1014T	Neutral	0.485
NPHS1	O60500-1.1	L1014V	Neutral	0.274
NPHS1	O60500-1.1	L1014W	Neutral	0.168
NPHS1	O60500-1.1	L1014Y	Neutral	0.192
NPHS1	O60500-1.1	A1015C	Pathogenic	0.969
NPHS1	O60500-1.1	A1015D	Pathogenic	0.966
NPHS1	O60500-1.1	A1015E	Pathogenic	0.982
NPHS1	O60500-1.1	A1015F	Pathogenic	0.993
NPHS1	O60500-1.1	A1015G	Pathogenic	0.947
NPHS1	O60500-1.1	A1015H	Pathogenic	0.934
NPHS1	O60500-1.1	A1015I	Pathogenic	0.994
NPHS1	O60500-1.1	A1015K	Pathogenic	0.994
NPHS1	O60500-1.1	A1015L	Pathogenic	0.993
NPHS1	O60500-1.1	A1015M	Pathogenic	0.987
NPHS1	O60500-1.1	A1015N	Pathogenic	0.961
NPHS1	O60500-1.1	A1015P	Pathogenic	0.939
NPHS1	O60500-1.1	A1015Q	Pathogenic	0.97
NPHS1	O60500-1.1	A1015R	Pathogenic	0.996
NPHS1	O60500-1.1	A1015S	Pathogenic	0.954
NPHS1	O60500-1.1	A1015T	Pathogenic	0.935
NPHS1	O60500-1.1	A1015V	Pathogenic	0.986
NPHS1	O60500-1.1	A1015W	Pathogenic	0.997
NPHS1	O60500-1.1	A1015Y	Pathogenic	0.98
NPHS1	O60500-1.1	S1016A	Neutral	0.045
NPHS1	O60500-1.1	S1016C	Neutral	0.063
NPHS1	O60500-1.1	S1016D	Neutral	0.069
NPHS1	O60500-1.1	S1016E	Neutral	0.085
NPHS1	O60500-1.1	S1016F	Neutral	0.324
NPHS1	O60500-1.1	S1016G	Neutral	0.03
NPHS1	O60500-1.1	S1016H	Neutral	0.039
NPHS1	O60500-1.1	S1016I	Neutral	0.274
NPHS1	O60500-1.1	S1016K	Neutral	0.225
NPHS1	O60500-1.1	S1016L	Neutral	0.245
NPHS1	O60500-1.1	S1016M	Neutral	0.194
NPHS1	O60500-1.1	S1016N	Neutral	0.088
NPHS1	O60500-1.1	S1016P	Neutral	0.048
NPHS1	O60500-1.1	S1016Q	Neutral	0.053
NPHS1	O60500-1.1	S1016R	Neutral	0.213
NPHS1	O60500-1.1	S1016T	Neutral	0.057
NPHS1	O60500-1.1	S1016V	Neutral	0.091
NPHS1	O60500-1.1	S1016W	Pathogenic	0.553
NPHS1	O60500-1.1	S1016Y	Neutral	0.139
NPHS1	O60500-1.1	N1017A	Pathogenic	0.996
NPHS1	O60500-1.1	N1017C	Pathogenic	0.996
NPHS1	O60500-1.1	N1017D	Pathogenic	0.993
NPHS1	O60500-1.1	N1017E	Pathogenic	0.989
NPHS1	O60500-1.1	N1017F	Pathogenic	0.999
NPHS1	O60500-1.1	N1017G	Pathogenic	0.998
NPHS1	O60500-1.1	N1017H	Pathogenic	0.998
NPHS1	O60500-1.1	N1017I	Pathogenic	0.999
NPHS1	O60500-1.1	N1017K	Pathogenic	0.997
NPHS1	O60500-1.1	N1017L	Pathogenic	0.999
NPHS1	O60500-1.1	N1017M	Pathogenic	0.999
NPHS1	O60500-1.1	N1017P	Pathogenic	0.996
NPHS1	O60500-1.1	N1017Q	Pathogenic	0.994
NPHS1	O60500-1.1	N1017R	Pathogenic	0.998
NPHS1	O60500-1.1	N1017S	Pathogenic	0.997
NPHS1	O60500-1.1	N1017T	Pathogenic	0.996
NPHS1	O60500-1.1	N1017V	Pathogenic	0.997
NPHS1	O60500-1.1	N1017W	Pathogenic	1.0
NPHS1	O60500-1.1	N1017Y	Pathogenic	0.999
NPHS1	O60500-1.1	A1018C	Pathogenic	0.901
NPHS1	O60500-1.1	A1018D	Pathogenic	0.893
NPHS1	O60500-1.1	A1018E	Pathogenic	0.94
NPHS1	O60500-1.1	A1018F	Pathogenic	0.977
NPHS1	O60500-1.1	A1018G	Pathogenic	0.84
NPHS1	O60500-1.1	A1018H	Pathogenic	0.805
NPHS1	O60500-1.1	A1018I	Pathogenic	0.981
NPHS1	O60500-1.1	A1018K	Pathogenic	0.98
NPHS1	O60500-1.1	A1018L	Pathogenic	0.978
NPHS1	O60500-1.1	A1018M	Pathogenic	0.956
NPHS1	O60500-1.1	A1018N	Pathogenic	0.88
NPHS1	O60500-1.1	A1018P	Pathogenic	0.819
NPHS1	O60500-1.1	A1018Q	Pathogenic	0.905
NPHS1	O60500-1.1	A1018R	Pathogenic	0.986
NPHS1	O60500-1.1	A1018S	Pathogenic	0.859
NPHS1	O60500-1.1	A1018T	Pathogenic	0.809
NPHS1	O60500-1.1	A1018V	Pathogenic	0.953
NPHS1	O60500-1.1	A1018W	Pathogenic	0.991
NPHS1	O60500-1.1	A1018Y	Pathogenic	0.935
NPHS1	O60500-1.1	L1019A	Pathogenic	0.935
NPHS1	O60500-1.1	L1019C	Pathogenic	0.77
NPHS1	O60500-1.1	L1019D	Pathogenic	0.924
NPHS1	O60500-1.1	L1019E	Pathogenic	0.907
NPHS1	O60500-1.1	L1019F	Pathogenic	0.507
NPHS1	O60500-1.1	L1019G	Pathogenic	0.914
NPHS1	O60500-1.1	L1019H	Pathogenic	0.714
NPHS1	O60500-1.1	L1019I	Pathogenic	0.643
NPHS1	O60500-1.1	L1019K	Pathogenic	0.957
NPHS1	O60500-1.1	L1019M	Pathogenic	0.757
NPHS1	O60500-1.1	L1019N	Pathogenic	0.926
NPHS1	O60500-1.1	L1019P	Pathogenic	0.669
NPHS1	O60500-1.1	L1019Q	Pathogenic	0.874
NPHS1	O60500-1.1	L1019R	Pathogenic	0.969
NPHS1	O60500-1.1	L1019S	Pathogenic	0.933
NPHS1	O60500-1.1	L1019T	Pathogenic	0.893
NPHS1	O60500-1.1	L1019V	Pathogenic	0.77
NPHS1	O60500-1.1	L1019W	Pathogenic	0.641
NPHS1	O60500-1.1	L1019Y	Pathogenic	0.677
NPHS1	O60500-1.1	G1020A	Pathogenic	0.965
NPHS1	O60500-1.1	G1020C	Pathogenic	0.972
NPHS1	O60500-1.1	G1020D	Pathogenic	0.985
NPHS1	O60500-1.1	G1020E	Pathogenic	0.982
NPHS1	O60500-1.1	G1020F	Pathogenic	0.997
NPHS1	O60500-1.1	G1020H	Pathogenic	0.969
NPHS1	O60500-1.1	G1020I	Pathogenic	0.995
NPHS1	O60500-1.1	G1020K	Pathogenic	0.994
NPHS1	O60500-1.1	G1020L	Pathogenic	0.994
NPHS1	O60500-1.1	G1020M	Pathogenic	0.992
NPHS1	O60500-1.1	G1020N	Pathogenic	0.988
NPHS1	O60500-1.1	G1020P	Pathogenic	0.975
NPHS1	O60500-1.1	G1020Q	Pathogenic	0.97
NPHS1	O60500-1.1	G1020R	Pathogenic	0.996
NPHS1	O60500-1.1	G1020S	Pathogenic	0.955
NPHS1	O60500-1.1	G1020T	Pathogenic	0.955
NPHS1	O60500-1.1	G1020V	Pathogenic	0.987
NPHS1	O60500-1.1	G1020W	Pathogenic	1.0
NPHS1	O60500-1.1	G1020Y	Pathogenic	0.992
NPHS1	O60500-1.1	D1021A	Pathogenic	0.815
NPHS1	O60500-1.1	D1021C	Pathogenic	0.837
NPHS1	O60500-1.1	D1021E	Pathogenic	0.822
NPHS1	O60500-1.1	D1021F	Pathogenic	0.977
NPHS1	O60500-1.1	D1021G	Pathogenic	0.867
NPHS1	O60500-1.1	D1021H	Pathogenic	0.844
NPHS1	O60500-1.1	D1021I	Pathogenic	0.971
NPHS1	O60500-1.1	D1021K	Pathogenic	0.746
NPHS1	O60500-1.1	D1021L	Pathogenic	0.951
NPHS1	O60500-1.1	D1021M	Pathogenic	0.935
NPHS1	O60500-1.1	D1021N	Pathogenic	0.707
NPHS1	O60500-1.1	D1021P	Pathogenic	0.875
NPHS1	O60500-1.1	D1021Q	Pathogenic	0.813
NPHS1	O60500-1.1	D1021R	Pathogenic	0.732
NPHS1	O60500-1.1	D1021S	Pathogenic	0.836
NPHS1	O60500-1.1	D1021T	Pathogenic	0.783
NPHS1	O60500-1.1	D1021V	Pathogenic	0.9
NPHS1	O60500-1.1	D1021W	Pathogenic	0.991
NPHS1	O60500-1.1	D1021Y	Pathogenic	0.935
NPHS1	O60500-1.1	S1022A	Pathogenic	0.958
NPHS1	O60500-1.1	S1022C	Pathogenic	0.971
NPHS1	O60500-1.1	S1022D	Pathogenic	0.973
NPHS1	O60500-1.1	S1022E	Pathogenic	0.979
NPHS1	O60500-1.1	S1022F	Pathogenic	0.996
NPHS1	O60500-1.1	S1022G	Pathogenic	0.939
NPHS1	O60500-1.1	S1022H	Pathogenic	0.952
NPHS1	O60500-1.1	S1022I	Pathogenic	0.995
NPHS1	O60500-1.1	S1022K	Pathogenic	0.993
NPHS1	O60500-1.1	S1022L	Pathogenic	0.994
NPHS1	O60500-1.1	S1022M	Pathogenic	0.992
NPHS1	O60500-1.1	S1022N	Pathogenic	0.979
NPHS1	O60500-1.1	S1022P	Pathogenic	0.961
NPHS1	O60500-1.1	S1022Q	Pathogenic	0.965
NPHS1	O60500-1.1	S1022R	Pathogenic	0.993
NPHS1	O60500-1.1	S1022T	Pathogenic	0.967
NPHS1	O60500-1.1	S1022V	Pathogenic	0.98
NPHS1	O60500-1.1	S1022W	Pathogenic	0.998
NPHS1	O60500-1.1	S1022Y	Pathogenic	0.988
NPHS1	O60500-1.1	G1023A	Neutral	0.122
NPHS1	O60500-1.1	G1023C	Neutral	0.152
NPHS1	O60500-1.1	G1023D	Neutral	0.247
NPHS1	O60500-1.1	G1023E	Neutral	0.216
NPHS1	O60500-1.1	G1023F	Pathogenic	0.655
NPHS1	O60500-1.1	G1023H	Neutral	0.139
NPHS1	O60500-1.1	G1023I	Pathogenic	0.501
NPHS1	O60500-1.1	G1023K	Neutral	0.463
NPHS1	O60500-1.1	G1023L	Neutral	0.463
NPHS1	O60500-1.1	G1023M	Neutral	0.39
NPHS1	O60500-1.1	G1023N	Neutral	0.3
NPHS1	O60500-1.1	G1023P	Neutral	0.166
NPHS1	O60500-1.1	G1023Q	Neutral	0.143
NPHS1	O60500-1.1	G1023R	Pathogenic	0.545
NPHS1	O60500-1.1	G1023S	Neutral	0.097
NPHS1	O60500-1.1	G1023T	Neutral	0.097
NPHS1	O60500-1.1	G1023V	Neutral	0.285
NPHS1	O60500-1.1	G1023W	Pathogenic	0.916
NPHS1	O60500-1.1	G1023Y	Neutral	0.389
NPHS1	O60500-1.1	L1024A	Pathogenic	0.526
NPHS1	O60500-1.1	L1024C	Neutral	0.206
NPHS1	O60500-1.1	L1024D	Neutral	0.485
NPHS1	O60500-1.1	L1024E	Neutral	0.43
NPHS1	O60500-1.1	L1024F	Neutral	0.074
NPHS1	O60500-1.1	L1024G	Neutral	0.453
NPHS1	O60500-1.1	L1024H	Neutral	0.162
NPHS1	O60500-1.1	L1024I	Neutral	0.123
NPHS1	O60500-1.1	L1024K	Pathogenic	0.633
NPHS1	O60500-1.1	L1024M	Neutral	0.195
NPHS1	O60500-1.1	L1024N	Neutral	0.493
NPHS1	O60500-1.1	L1024P	Neutral	0.136
NPHS1	O60500-1.1	L1024Q	Neutral	0.349
NPHS1	O60500-1.1	L1024R	Pathogenic	0.706
NPHS1	O60500-1.1	L1024S	Pathogenic	0.518
NPHS1	O60500-1.1	L1024T	Neutral	0.393
NPHS1	O60500-1.1	L1024V	Neutral	0.206
NPHS1	O60500-1.1	L1024W	Neutral	0.122
NPHS1	O60500-1.1	L1024Y	Neutral	0.14
NPHS1	O60500-1.1	A1025C	Neutral	0.28
NPHS1	O60500-1.1	A1025D	Neutral	0.264
NPHS1	O60500-1.1	A1025E	Neutral	0.402
NPHS1	O60500-1.1	A1025F	Pathogenic	0.649
NPHS1	O60500-1.1	A1025G	Neutral	0.184
NPHS1	O60500-1.1	A1025H	Neutral	0.151
NPHS1	O60500-1.1	A1025I	Pathogenic	0.685
NPHS1	O60500-1.1	A1025K	Pathogenic	0.677
NPHS1	O60500-1.1	A1025L	Pathogenic	0.651
NPHS1	O60500-1.1	A1025M	Neutral	0.481
NPHS1	O60500-1.1	A1025N	Neutral	0.239
NPHS1	O60500-1.1	A1025P	Neutral	0.162
NPHS1	O60500-1.1	A1025Q	Neutral	0.289
NPHS1	O60500-1.1	A1025R	Pathogenic	0.745
NPHS1	O60500-1.1	A1025S	Neutral	0.207
NPHS1	O60500-1.1	A1025T	Neutral	0.154
NPHS1	O60500-1.1	A1025V	Neutral	0.464
NPHS1	O60500-1.1	A1025W	Pathogenic	0.827
NPHS1	O60500-1.1	A1025Y	Neutral	0.383
NPHS1	O60500-1.1	D1026A	Pathogenic	0.725
NPHS1	O60500-1.1	D1026C	Pathogenic	0.755
NPHS1	O60500-1.1	D1026E	Pathogenic	0.734
NPHS1	O60500-1.1	D1026F	Pathogenic	0.962
NPHS1	O60500-1.1	D1026G	Pathogenic	0.795
NPHS1	O60500-1.1	D1026H	Pathogenic	0.764
NPHS1	O60500-1.1	D1026I	Pathogenic	0.953
NPHS1	O60500-1.1	D1026K	Pathogenic	0.637
NPHS1	O60500-1.1	D1026L	Pathogenic	0.921
NPHS1	O60500-1.1	D1026M	Pathogenic	0.896
NPHS1	O60500-1.1	D1026N	Pathogenic	0.59
NPHS1	O60500-1.1	D1026P	Pathogenic	0.808
NPHS1	O60500-1.1	D1026Q	Pathogenic	0.723
NPHS1	O60500-1.1	D1026R	Pathogenic	0.621
NPHS1	O60500-1.1	D1026S	Pathogenic	0.753
NPHS1	O60500-1.1	D1026T	Pathogenic	0.684
NPHS1	O60500-1.1	D1026V	Pathogenic	0.844
NPHS1	O60500-1.1	D1026W	Pathogenic	0.985
NPHS1	O60500-1.1	D1026Y	Pathogenic	0.896
NPHS1	O60500-1.1	K1027A	Pathogenic	0.551
NPHS1	O60500-1.1	K1027C	Neutral	0.49
NPHS1	O60500-1.1	K1027D	Neutral	0.123
NPHS1	O60500-1.1	K1027E	Neutral	0.199
NPHS1	O60500-1.1	K1027F	Pathogenic	0.501
NPHS1	O60500-1.1	K1027G	Neutral	0.449
NPHS1	O60500-1.1	K1027H	Neutral	0.221
NPHS1	O60500-1.1	K1027I	Pathogenic	0.571
NPHS1	O60500-1.1	K1027L	Pathogenic	0.63
NPHS1	O60500-1.1	K1027M	Pathogenic	0.558
NPHS1	O60500-1.1	K1027N	Neutral	0.193
NPHS1	O60500-1.1	K1027P	Pathogenic	0.568
NPHS1	O60500-1.1	K1027Q	Neutral	0.291
NPHS1	O60500-1.1	K1027R	Neutral	0.141
NPHS1	O60500-1.1	K1027S	Neutral	0.488
NPHS1	O60500-1.1	K1027T	Neutral	0.381
NPHS1	O60500-1.1	K1027V	Pathogenic	0.565
NPHS1	O60500-1.1	K1027W	Pathogenic	0.795
NPHS1	O60500-1.1	K1027Y	Neutral	0.335
NPHS1	O60500-1.1	G1028A	Pathogenic	0.661
NPHS1	O60500-1.1	G1028C	Pathogenic	0.715
NPHS1	O60500-1.1	G1028D	Pathogenic	0.821
NPHS1	O60500-1.1	G1028E	Pathogenic	0.794
NPHS1	O60500-1.1	G1028F	Pathogenic	0.964
NPHS1	O60500-1.1	G1028H	Pathogenic	0.692
NPHS1	O60500-1.1	G1028I	Pathogenic	0.933
NPHS1	O60500-1.1	G1028K	Pathogenic	0.923
NPHS1	O60500-1.1	G1028L	Pathogenic	0.923
NPHS1	O60500-1.1	G1028M	Pathogenic	0.899
NPHS1	O60500-1.1	G1028N	Pathogenic	0.857
NPHS1	O60500-1.1	G1028P	Pathogenic	0.735
NPHS1	O60500-1.1	G1028Q	Pathogenic	0.7
NPHS1	O60500-1.1	G1028R	Pathogenic	0.944
NPHS1	O60500-1.1	G1028S	Pathogenic	0.6
NPHS1	O60500-1.1	G1028T	Pathogenic	0.6
NPHS1	O60500-1.1	G1028V	Pathogenic	0.848
NPHS1	O60500-1.1	G1028W	Pathogenic	0.993
NPHS1	O60500-1.1	G1028Y	Pathogenic	0.899
NPHS1	O60500-1.1	T1029A	Neutral	0.003
NPHS1	O60500-1.1	T1029C	Neutral	0.003
NPHS1	O60500-1.1	T1029D	Neutral	0.004
NPHS1	O60500-1.1	T1029E	Neutral	0.005
NPHS1	O60500-1.1	T1029F	Neutral	0.015
NPHS1	O60500-1.1	T1029G	Neutral	0.002
NPHS1	O60500-1.1	T1029H	Neutral	0.001
NPHS1	O60500-1.1	T1029I	Neutral	0.018
NPHS1	O60500-1.1	T1029K	Neutral	0.015
NPHS1	O60500-1.1	T1029L	Neutral	0.015
NPHS1	O60500-1.1	T1029M	Neutral	0.008
NPHS1	O60500-1.1	T1029N	Neutral	0.005
NPHS1	O60500-1.1	T1029P	Neutral	0.002
NPHS1	O60500-1.1	T1029Q	Neutral	0.003
NPHS1	O60500-1.1	T1029R	Neutral	0.02
NPHS1	O60500-1.1	T1029S	Neutral	0.005
NPHS1	O60500-1.1	T1029V	Neutral	0.007
NPHS1	O60500-1.1	T1029W	Neutral	0.056
NPHS1	O60500-1.1	T1029Y	Neutral	0.005
NPHS1	O60500-1.1	Q1030A	Neutral	0.111
NPHS1	O60500-1.1	Q1030C	Neutral	0.089
NPHS1	O60500-1.1	Q1030D	Neutral	0.098
NPHS1	O60500-1.1	Q1030E	Neutral	0.115
NPHS1	O60500-1.1	Q1030F	Neutral	0.215
NPHS1	O60500-1.1	Q1030G	Neutral	0.076
NPHS1	O60500-1.1	Q1030H	Neutral	0.049
NPHS1	O60500-1.1	Q1030I	Neutral	0.178
NPHS1	O60500-1.1	Q1030K	Neutral	0.177
NPHS1	O60500-1.1	Q1030L	Neutral	0.217
NPHS1	O60500-1.1	Q1030M	Neutral	0.234
NPHS1	O60500-1.1	Q1030N	Neutral	0.07
NPHS1	O60500-1.1	Q1030P	Neutral	0.118
NPHS1	O60500-1.1	Q1030R	Neutral	0.23
NPHS1	O60500-1.1	Q1030S	Neutral	0.088
NPHS1	O60500-1.1	Q1030T	Neutral	0.059
NPHS1	O60500-1.1	Q1030V	Neutral	0.116
NPHS1	O60500-1.1	Q1030W	Pathogenic	0.612
NPHS1	O60500-1.1	Q1030Y	Neutral	0.17
NPHS1	O60500-1.1	L1031A	Neutral	0.258
NPHS1	O60500-1.1	L1031C	Neutral	0.075
NPHS1	O60500-1.1	L1031D	Neutral	0.228
NPHS1	O60500-1.1	L1031E	Neutral	0.191
NPHS1	O60500-1.1	L1031F	Neutral	0.024
NPHS1	O60500-1.1	L1031G	Neutral	0.206
NPHS1	O60500-1.1	L1031H	Neutral	0.057
NPHS1	O60500-1.1	L1031I	Neutral	0.042
NPHS1	O60500-1.1	L1031K	Neutral	0.351
NPHS1	O60500-1.1	L1031M	Neutral	0.07
NPHS1	O60500-1.1	L1031N	Neutral	0.233
NPHS1	O60500-1.1	L1031P	Neutral	0.047
NPHS1	O60500-1.1	L1031Q	Neutral	0.144
NPHS1	O60500-1.1	L1031R	Neutral	0.429
NPHS1	O60500-1.1	L1031S	Neutral	0.252
NPHS1	O60500-1.1	L1031T	Neutral	0.169
NPHS1	O60500-1.1	L1031V	Neutral	0.075
NPHS1	O60500-1.1	L1031W	Neutral	0.042
NPHS1	O60500-1.1	L1031Y	Neutral	0.049
NPHS1	O60500-1.1	P1032A	Neutral	0.005
NPHS1	O60500-1.1	P1032C	Neutral	0.001
NPHS1	O60500-1.1	P1032D	Neutral	0.015
NPHS1	O60500-1.1	P1032E	Neutral	0.018
NPHS1	O60500-1.1	P1032F	Neutral	0.007
NPHS1	O60500-1.1	P1032G	Neutral	0.008
NPHS1	O60500-1.1	P1032H	Neutral	0.005
NPHS1	O60500-1.1	P1032I	Neutral	0.008
NPHS1	O60500-1.1	P1032K	Neutral	0.055
NPHS1	O60500-1.1	P1032L	Neutral	0.007
NPHS1	O60500-1.1	P1032M	Neutral	0.005
NPHS1	O60500-1.1	P1032N	Neutral	0.009
NPHS1	O60500-1.1	P1032Q	Neutral	0.011
NPHS1	O60500-1.1	P1032R	Neutral	0.052
NPHS1	O60500-1.1	P1032S	Neutral	0.007
NPHS1	O60500-1.1	P1032T	Neutral	0.003
NPHS1	O60500-1.1	P1032V	Neutral	0.003
NPHS1	O60500-1.1	P1032W	Neutral	0.026
NPHS1	O60500-1.1	P1032Y	Neutral	0.003
NPHS1	O60500-1.1	I1033A	Pathogenic	0.974
NPHS1	O60500-1.1	I1033C	Pathogenic	0.899
NPHS1	O60500-1.1	I1033D	Pathogenic	0.98
NPHS1	O60500-1.1	I1033E	Pathogenic	0.963
NPHS1	O60500-1.1	I1033F	Pathogenic	0.68
NPHS1	O60500-1.1	I1033G	Pathogenic	0.966
NPHS1	O60500-1.1	I1033H	Pathogenic	0.87
NPHS1	O60500-1.1	I1033K	Pathogenic	0.976
NPHS1	O60500-1.1	I1033L	Pathogenic	0.806
NPHS1	O60500-1.1	I1033M	Pathogenic	0.848
NPHS1	O60500-1.1	I1033N	Pathogenic	0.971
NPHS1	O60500-1.1	I1033P	Pathogenic	0.844
NPHS1	O60500-1.1	I1033Q	Pathogenic	0.925
NPHS1	O60500-1.1	I1033R	Pathogenic	0.982
NPHS1	O60500-1.1	I1033S	Pathogenic	0.974
NPHS1	O60500-1.1	I1033T	Pathogenic	0.957
NPHS1	O60500-1.1	I1033V	Pathogenic	0.952
NPHS1	O60500-1.1	I1033W	Pathogenic	0.702
NPHS1	O60500-1.1	I1033Y	Pathogenic	0.849
NPHS1	O60500-1.1	T1034A	Pathogenic	0.909
NPHS1	O60500-1.1	T1034C	Pathogenic	0.921
NPHS1	O60500-1.1	T1034D	Pathogenic	0.942
NPHS1	O60500-1.1	T1034E	Pathogenic	0.949
NPHS1	O60500-1.1	T1034F	Pathogenic	0.984
NPHS1	O60500-1.1	T1034G	Pathogenic	0.906
NPHS1	O60500-1.1	T1034H	Pathogenic	0.831
NPHS1	O60500-1.1	T1034I	Pathogenic	0.986
NPHS1	O60500-1.1	T1034K	Pathogenic	0.983
NPHS1	O60500-1.1	T1034L	Pathogenic	0.984
NPHS1	O60500-1.1	T1034M	Pathogenic	0.968
NPHS1	O60500-1.1	T1034N	Pathogenic	0.951
NPHS1	O60500-1.1	T1034P	Pathogenic	0.878
NPHS1	O60500-1.1	T1034Q	Pathogenic	0.918
NPHS1	O60500-1.1	T1034R	Pathogenic	0.988
NPHS1	O60500-1.1	T1034S	Pathogenic	0.949
NPHS1	O60500-1.1	T1034V	Pathogenic	0.965
NPHS1	O60500-1.1	T1034W	Pathogenic	0.996
NPHS1	O60500-1.1	T1034Y	Pathogenic	0.952
NPHS1	O60500-1.1	T1035A	Pathogenic	0.97
NPHS1	O60500-1.1	T1035C	Pathogenic	0.974
NPHS1	O60500-1.1	T1035D	Pathogenic	0.981
NPHS1	O60500-1.1	T1035E	Pathogenic	0.984
NPHS1	O60500-1.1	T1035F	Pathogenic	0.995
NPHS1	O60500-1.1	T1035G	Pathogenic	0.969
NPHS1	O60500-1.1	T1035H	Pathogenic	0.941
NPHS1	O60500-1.1	T1035I	Pathogenic	0.996
NPHS1	O60500-1.1	T1035K	Pathogenic	0.995
NPHS1	O60500-1.1	T1035L	Pathogenic	0.995
NPHS1	O60500-1.1	T1035M	Pathogenic	0.99
NPHS1	O60500-1.1	T1035N	Pathogenic	0.984
NPHS1	O60500-1.1	T1035P	Pathogenic	0.959
NPHS1	O60500-1.1	T1035Q	Pathogenic	0.973
NPHS1	O60500-1.1	T1035R	Pathogenic	0.996
NPHS1	O60500-1.1	T1035S	Pathogenic	0.984
NPHS1	O60500-1.1	T1035V	Pathogenic	0.989
NPHS1	O60500-1.1	T1035W	Pathogenic	0.999
NPHS1	O60500-1.1	T1035Y	Pathogenic	0.985
NPHS1	O60500-1.1	P1036A	Neutral	0.072
NPHS1	O60500-1.1	P1036C	Neutral	0.017
NPHS1	O60500-1.1	P1036D	Neutral	0.186
NPHS1	O60500-1.1	P1036E	Neutral	0.223
NPHS1	O60500-1.1	P1036F	Neutral	0.094
NPHS1	O60500-1.1	P1036G	Neutral	0.114
NPHS1	O60500-1.1	P1036H	Neutral	0.07
NPHS1	O60500-1.1	P1036I	Neutral	0.109
NPHS1	O60500-1.1	P1036K	Neutral	0.472
NPHS1	O60500-1.1	P1036L	Neutral	0.095
NPHS1	O60500-1.1	P1036M	Neutral	0.072
NPHS1	O60500-1.1	P1036N	Neutral	0.118
NPHS1	O60500-1.1	P1036Q	Neutral	0.148
NPHS1	O60500-1.1	P1036R	Neutral	0.454
NPHS1	O60500-1.1	P1036S	Neutral	0.1
NPHS1	O60500-1.1	P1036T	Neutral	0.049
NPHS1	O60500-1.1	P1036V	Neutral	0.047
NPHS1	O60500-1.1	P1036W	Neutral	0.287
NPHS1	O60500-1.1	P1036Y	Neutral	0.05
NPHS1	O60500-1.1	G1037A	Neutral	0.392
NPHS1	O60500-1.1	G1037C	Neutral	0.454
NPHS1	O60500-1.1	G1037D	Pathogenic	0.602
NPHS1	O60500-1.1	G1037E	Pathogenic	0.561
NPHS1	O60500-1.1	G1037F	Pathogenic	0.898
NPHS1	O60500-1.1	G1037H	Neutral	0.427
NPHS1	O60500-1.1	G1037I	Pathogenic	0.823
NPHS1	O60500-1.1	G1037K	Pathogenic	0.799
NPHS1	O60500-1.1	G1037L	Pathogenic	0.799
NPHS1	O60500-1.1	G1037M	Pathogenic	0.747
NPHS1	O60500-1.1	G1037N	Pathogenic	0.664
NPHS1	O60500-1.1	G1037P	Neutral	0.479
NPHS1	O60500-1.1	G1037Q	Neutral	0.435
NPHS1	O60500-1.1	G1037R	Pathogenic	0.847
NPHS1	O60500-1.1	G1037S	Neutral	0.331
NPHS1	O60500-1.1	G1037T	Neutral	0.332
NPHS1	O60500-1.1	G1037V	Pathogenic	0.648
NPHS1	O60500-1.1	G1037W	Pathogenic	0.981
NPHS1	O60500-1.1	G1037Y	Pathogenic	0.747
NPHS1	O60500-1.1	L1038A	Neutral	0.43
NPHS1	O60500-1.1	L1038C	Neutral	0.15
NPHS1	O60500-1.1	L1038D	Neutral	0.39
NPHS1	O60500-1.1	L1038E	Neutral	0.339
NPHS1	O60500-1.1	L1038F	Neutral	0.052
NPHS1	O60500-1.1	L1038G	Neutral	0.36
NPHS1	O60500-1.1	L1038H	Neutral	0.117
NPHS1	O60500-1.1	L1038I	Neutral	0.087
NPHS1	O60500-1.1	L1038K	Pathogenic	0.54
NPHS1	O60500-1.1	L1038M	Neutral	0.141
NPHS1	O60500-1.1	L1038N	Neutral	0.398
NPHS1	O60500-1.1	L1038P	Neutral	0.096
NPHS1	O60500-1.1	L1038Q	Neutral	0.267
NPHS1	O60500-1.1	L1038R	Pathogenic	0.62
NPHS1	O60500-1.1	L1038S	Neutral	0.423
NPHS1	O60500-1.1	L1038T	Neutral	0.306
NPHS1	O60500-1.1	L1038V	Neutral	0.15
NPHS1	O60500-1.1	L1038W	Neutral	0.086
NPHS1	O60500-1.1	L1038Y	Neutral	0.1
NPHS1	O60500-1.1	H1039A	Neutral	0.001
NPHS1	O60500-1.1	H1039C	Neutral	0.002
NPHS1	O60500-1.1	H1039D	Neutral	0.003
NPHS1	O60500-1.1	H1039E	Neutral	0.003
NPHS1	O60500-1.1	H1039F	Neutral	0.008
NPHS1	O60500-1.1	H1039G	Neutral	0.002
NPHS1	O60500-1.1	H1039I	Neutral	0.003
NPHS1	O60500-1.1	H1039K	Neutral	0.004
NPHS1	O60500-1.1	H1039L	Neutral	0.003
NPHS1	O60500-1.1	H1039M	Neutral	0.002
NPHS1	O60500-1.1	H1039N	Neutral	0.005
NPHS1	O60500-1.1	H1039P	Neutral	0.001
NPHS1	O60500-1.1	H1039Q	Neutral	0.001
NPHS1	O60500-1.1	H1039R	Neutral	0.008
NPHS1	O60500-1.1	H1039S	Neutral	0.002
NPHS1	O60500-1.1	H1039T	Neutral	0.001
NPHS1	O60500-1.1	H1039V	Neutral	0.001
NPHS1	O60500-1.1	H1039W	Neutral	0.021
NPHS1	O60500-1.1	H1039Y	Neutral	0.009
NPHS1	O60500-1.1	Q1040A	Neutral	0.307
NPHS1	O60500-1.1	Q1040C	Neutral	0.257
NPHS1	O60500-1.1	Q1040D	Neutral	0.279
NPHS1	O60500-1.1	Q1040E	Neutral	0.316
NPHS1	O60500-1.1	Q1040F	Neutral	0.494
NPHS1	O60500-1.1	Q1040G	Neutral	0.227
NPHS1	O60500-1.1	Q1040H	Neutral	0.155
NPHS1	O60500-1.1	Q1040I	Neutral	0.435
NPHS1	O60500-1.1	Q1040K	Neutral	0.433
NPHS1	O60500-1.1	Q1040L	Neutral	0.496
NPHS1	O60500-1.1	Q1040M	Pathogenic	0.521
NPHS1	O60500-1.1	Q1040N	Neutral	0.211
NPHS1	O60500-1.1	Q1040P	Neutral	0.321
NPHS1	O60500-1.1	Q1040R	Pathogenic	0.515
NPHS1	O60500-1.1	Q1040S	Neutral	0.255
NPHS1	O60500-1.1	Q1040T	Neutral	0.182
NPHS1	O60500-1.1	Q1040V	Neutral	0.319
NPHS1	O60500-1.1	Q1040W	Pathogenic	0.849
NPHS1	O60500-1.1	Q1040Y	Neutral	0.421
NPHS1	O60500-1.1	P1041A	Neutral	0.033
NPHS1	O60500-1.1	P1041C	Neutral	0.008
NPHS1	O60500-1.1	P1041D	Neutral	0.092
NPHS1	O60500-1.1	P1041E	Neutral	0.113
NPHS1	O60500-1.1	P1041F	Neutral	0.044
NPHS1	O60500-1.1	P1041G	Neutral	0.054
NPHS1	O60500-1.1	P1041H	Neutral	0.032
NPHS1	O60500-1.1	P1041I	Neutral	0.051
NPHS1	O60500-1.1	P1041K	Neutral	0.284
NPHS1	O60500-1.1	P1041L	Neutral	0.045
NPHS1	O60500-1.1	P1041M	Neutral	0.033
NPHS1	O60500-1.1	P1041N	Neutral	0.056
NPHS1	O60500-1.1	P1041Q	Neutral	0.071
NPHS1	O60500-1.1	P1041R	Neutral	0.269
NPHS1	O60500-1.1	P1041S	Neutral	0.047
NPHS1	O60500-1.1	P1041T	Neutral	0.022
NPHS1	O60500-1.1	P1041V	Neutral	0.021
NPHS1	O60500-1.1	P1041W	Neutral	0.151
NPHS1	O60500-1.1	P1041Y	Neutral	0.023
NPHS1	O60500-1.1	S1042A	Neutral	0.014
NPHS1	O60500-1.1	S1042C	Neutral	0.02
NPHS1	O60500-1.1	S1042D	Neutral	0.022
NPHS1	O60500-1.1	S1042E	Neutral	0.027
NPHS1	O60500-1.1	S1042F	Neutral	0.125
NPHS1	O60500-1.1	S1042G	Neutral	0.009
NPHS1	O60500-1.1	S1042H	Neutral	0.012
NPHS1	O60500-1.1	S1042I	Neutral	0.101
NPHS1	O60500-1.1	S1042K	Neutral	0.08
NPHS1	O60500-1.1	S1042L	Neutral	0.088
NPHS1	O60500-1.1	S1042M	Neutral	0.067
NPHS1	O60500-1.1	S1042N	Neutral	0.028
NPHS1	O60500-1.1	S1042P	Neutral	0.015
NPHS1	O60500-1.1	S1042Q	Neutral	0.017
NPHS1	O60500-1.1	S1042R	Neutral	0.075
NPHS1	O60500-1.1	S1042T	Neutral	0.018
NPHS1	O60500-1.1	S1042V	Neutral	0.029
NPHS1	O60500-1.1	S1042W	Neutral	0.27
NPHS1	O60500-1.1	S1042Y	Neutral	0.046
NPHS1	O60500-1.1	G1043A	Neutral	0.009
NPHS1	O60500-1.1	G1043C	Neutral	0.011
NPHS1	O60500-1.1	G1043D	Neutral	0.02
NPHS1	O60500-1.1	G1043E	Neutral	0.017
NPHS1	O60500-1.1	G1043F	Neutral	0.105
NPHS1	O60500-1.1	G1043H	Neutral	0.01
NPHS1	O60500-1.1	G1043I	Neutral	0.059
NPHS1	O60500-1.1	G1043K	Neutral	0.051
NPHS1	O60500-1.1	G1043L	Neutral	0.051
NPHS1	O60500-1.1	G1043M	Neutral	0.038
NPHS1	O60500-1.1	G1043N	Neutral	0.026
NPHS1	O60500-1.1	G1043P	Neutral	0.012
NPHS1	O60500-1.1	G1043Q	Neutral	0.01
NPHS1	O60500-1.1	G1043R	Neutral	0.069
NPHS1	O60500-1.1	G1043S	Neutral	0.007
NPHS1	O60500-1.1	G1043T	Neutral	0.007
NPHS1	O60500-1.1	G1043V	Neutral	0.024
NPHS1	O60500-1.1	G1043W	Neutral	0.404
NPHS1	O60500-1.1	G1043Y	Neutral	0.038
NPHS1	O60500-1.1	E1044A	Neutral	0.07
NPHS1	O60500-1.1	E1044C	Neutral	0.038
NPHS1	O60500-1.1	E1044D	Neutral	0.041
NPHS1	O60500-1.1	E1044F	Neutral	0.174
NPHS1	O60500-1.1	E1044G	Neutral	0.048
NPHS1	O60500-1.1	E1044H	Neutral	0.038
NPHS1	O60500-1.1	E1044I	Neutral	0.143
NPHS1	O60500-1.1	E1044K	Neutral	0.045
NPHS1	O60500-1.1	E1044L	Neutral	0.125
NPHS1	O60500-1.1	E1044M	Neutral	0.096
NPHS1	O60500-1.1	E1044N	Neutral	0.014
NPHS1	O60500-1.1	E1044P	Neutral	0.075
NPHS1	O60500-1.1	E1044Q	Neutral	0.046
NPHS1	O60500-1.1	E1044R	Neutral	0.043
NPHS1	O60500-1.1	E1044S	Neutral	0.055
NPHS1	O60500-1.1	E1044T	Neutral	0.037
NPHS1	O60500-1.1	E1044V	Neutral	0.074
NPHS1	O60500-1.1	E1044W	Neutral	0.449
NPHS1	O60500-1.1	E1044Y	Neutral	0.096
NPHS1	O60500-1.1	P1045A	Neutral	0.025
NPHS1	O60500-1.1	P1045C	Neutral	0.006
NPHS1	O60500-1.1	P1045D	Neutral	0.07
NPHS1	O60500-1.1	P1045E	Neutral	0.086
NPHS1	O60500-1.1	P1045F	Neutral	0.033
NPHS1	O60500-1.1	P1045G	Neutral	0.041
NPHS1	O60500-1.1	P1045H	Neutral	0.024
NPHS1	O60500-1.1	P1045I	Neutral	0.039
NPHS1	O60500-1.1	P1045K	Neutral	0.228
NPHS1	O60500-1.1	P1045L	Neutral	0.034
NPHS1	O60500-1.1	P1045M	Neutral	0.025
NPHS1	O60500-1.1	P1045N	Neutral	0.042
NPHS1	O60500-1.1	P1045Q	Neutral	0.054
NPHS1	O60500-1.1	P1045R	Neutral	0.216
NPHS1	O60500-1.1	P1045S	Neutral	0.036
NPHS1	O60500-1.1	P1045T	Neutral	0.017
NPHS1	O60500-1.1	P1045V	Neutral	0.016
NPHS1	O60500-1.1	P1045W	Neutral	0.117
NPHS1	O60500-1.1	P1045Y	Neutral	0.017
NPHS1	O60500-1.1	E1046A	Neutral	0.003
NPHS1	O60500-1.1	E1046C	Neutral	0.002
NPHS1	O60500-1.1	E1046D	Neutral	0.002
NPHS1	O60500-1.1	E1046F	Neutral	0.009
NPHS1	O60500-1.1	E1046G	Neutral	0.002
NPHS1	O60500-1.1	E1046H	Neutral	0.002
NPHS1	O60500-1.1	E1046I	Neutral	0.007
NPHS1	O60500-1.1	E1046K	Neutral	0.002
NPHS1	O60500-1.1	E1046L	Neutral	0.006
NPHS1	O60500-1.1	E1046M	Neutral	0.005
NPHS1	O60500-1.1	E1046N	Neutral	0.001
NPHS1	O60500-1.1	E1046P	Neutral	0.004
NPHS1	O60500-1.1	E1046Q	Neutral	0.002
NPHS1	O60500-1.1	E1046R	Neutral	0.002
NPHS1	O60500-1.1	E1046S	Neutral	0.003
NPHS1	O60500-1.1	E1046T	Neutral	0.002
NPHS1	O60500-1.1	E1046V	Neutral	0.004
NPHS1	O60500-1.1	E1046W	Neutral	0.035
NPHS1	O60500-1.1	E1046Y	Neutral	0.005
NPHS1	O60500-1.1	D1047A	Neutral	0.002
NPHS1	O60500-1.1	D1047C	Neutral	0.003
NPHS1	O60500-1.1	D1047E	Neutral	0.003
NPHS1	O60500-1.1	D1047F	Neutral	0.024
NPHS1	O60500-1.1	D1047G	Neutral	0.004
NPHS1	O60500-1.1	D1047H	Neutral	0.003
NPHS1	O60500-1.1	D1047I	Neutral	0.019
NPHS1	O60500-1.1	D1047K	Neutral	0.002
NPHS1	O60500-1.1	D1047L	Neutral	0.011
NPHS1	O60500-1.1	D1047M	Neutral	0.008
NPHS1	O60500-1.1	D1047N	Neutral	0.001
NPHS1	O60500-1.1	D1047P	Neutral	0.004
NPHS1	O60500-1.1	D1047Q	Neutral	0.002
NPHS1	O60500-1.1	D1047R	Neutral	0.002
NPHS1	O60500-1.1	D1047S	Neutral	0.003
NPHS1	O60500-1.1	D1047T	Neutral	0.002
NPHS1	O60500-1.1	D1047V	Neutral	0.005
NPHS1	O60500-1.1	D1047W	Neutral	0.059
NPHS1	O60500-1.1	D1047Y	Neutral	0.008
NPHS1	O60500-1.1	Q1048A	Neutral	0.086
NPHS1	O60500-1.1	Q1048C	Neutral	0.069
NPHS1	O60500-1.1	Q1048D	Neutral	0.076
NPHS1	O60500-1.1	Q1048E	Neutral	0.089
NPHS1	O60500-1.1	Q1048F	Neutral	0.172
NPHS1	O60500-1.1	Q1048G	Neutral	0.059
NPHS1	O60500-1.1	Q1048H	Neutral	0.038
NPHS1	O60500-1.1	Q1048I	Neutral	0.141
NPHS1	O60500-1.1	Q1048K	Neutral	0.14
NPHS1	O60500-1.1	Q1048L	Neutral	0.173
NPHS1	O60500-1.1	Q1048M	Neutral	0.188
NPHS1	O60500-1.1	Q1048N	Neutral	0.054
NPHS1	O60500-1.1	Q1048P	Neutral	0.092
NPHS1	O60500-1.1	Q1048R	Neutral	0.184
NPHS1	O60500-1.1	Q1048S	Neutral	0.068
NPHS1	O60500-1.1	Q1048T	Neutral	0.045
NPHS1	O60500-1.1	Q1048V	Neutral	0.09
NPHS1	O60500-1.1	Q1048W	Pathogenic	0.544
NPHS1	O60500-1.1	Q1048Y	Neutral	0.134
NPHS1	O60500-1.1	L1049A	Neutral	0.027
NPHS1	O60500-1.1	L1049C	Neutral	0.006
NPHS1	O60500-1.1	L1049D	Neutral	0.023
NPHS1	O60500-1.1	L1049E	Neutral	0.018
NPHS1	O60500-1.1	L1049F	Neutral	0.002
NPHS1	O60500-1.1	L1049G	Neutral	0.02
NPHS1	O60500-1.1	L1049H	Neutral	0.005
NPHS1	O60500-1.1	L1049I	Neutral	0.003
NPHS1	O60500-1.1	L1049K	Neutral	0.041
NPHS1	O60500-1.1	L1049M	Neutral	0.006
NPHS1	O60500-1.1	L1049N	Neutral	0.024
NPHS1	O60500-1.1	L1049P	Neutral	0.004
NPHS1	O60500-1.1	L1049Q	Neutral	0.013
NPHS1	O60500-1.1	L1049R	Neutral	0.056
NPHS1	O60500-1.1	L1049S	Neutral	0.026
NPHS1	O60500-1.1	L1049T	Neutral	0.016
NPHS1	O60500-1.1	L1049V	Neutral	0.006
NPHS1	O60500-1.1	L1049W	Neutral	0.003
NPHS1	O60500-1.1	L1049Y	Neutral	0.004
NPHS1	O60500-1.1	P1050A	Neutral	0.351
NPHS1	O60500-1.1	P1050C	Neutral	0.111
NPHS1	O60500-1.1	P1050D	Pathogenic	0.615
NPHS1	O60500-1.1	P1050E	Pathogenic	0.668
NPHS1	O60500-1.1	P1050F	Neutral	0.422
NPHS1	O60500-1.1	P1050G	Neutral	0.473
NPHS1	O60500-1.1	P1050H	Neutral	0.346
NPHS1	O60500-1.1	P1050I	Neutral	0.462
NPHS1	O60500-1.1	P1050K	Pathogenic	0.862
NPHS1	O60500-1.1	P1050L	Neutral	0.425
NPHS1	O60500-1.1	P1050M	Neutral	0.354
NPHS1	O60500-1.1	P1050N	Neutral	0.484
NPHS1	O60500-1.1	P1050Q	Pathogenic	0.548
NPHS1	O60500-1.1	P1050R	Pathogenic	0.854
NPHS1	O60500-1.1	P1050S	Neutral	0.439
NPHS1	O60500-1.1	P1050T	Neutral	0.267
NPHS1	O60500-1.1	P1050V	Neutral	0.255
NPHS1	O60500-1.1	P1050W	Pathogenic	0.738
NPHS1	O60500-1.1	P1050Y	Neutral	0.268
NPHS1	O60500-1.1	T1051A	Neutral	0.063
NPHS1	O60500-1.1	T1051C	Neutral	0.073
NPHS1	O60500-1.1	T1051D	Neutral	0.098
NPHS1	O60500-1.1	T1051E	Neutral	0.111
NPHS1	O60500-1.1	T1051F	Neutral	0.285
NPHS1	O60500-1.1	T1051G	Neutral	0.06
NPHS1	O60500-1.1	T1051H	Neutral	0.032
NPHS1	O60500-1.1	T1051I	Neutral	0.319
NPHS1	O60500-1.1	T1051K	Neutral	0.279
NPHS1	O60500-1.1	T1051L	Neutral	0.286
NPHS1	O60500-1.1	T1051M	Neutral	0.166
NPHS1	O60500-1.1	T1051N	Neutral	0.114
NPHS1	O60500-1.1	T1051P	Neutral	0.046
NPHS1	O60500-1.1	T1051Q	Neutral	0.07
NPHS1	O60500-1.1	T1051R	Neutral	0.35
NPHS1	O60500-1.1	T1051S	Neutral	0.11
NPHS1	O60500-1.1	T1051V	Neutral	0.157
NPHS1	O60500-1.1	T1051W	Pathogenic	0.605
NPHS1	O60500-1.1	T1051Y	Neutral	0.118
NPHS1	O60500-1.1	E1052A	Neutral	0.115
NPHS1	O60500-1.1	E1052C	Neutral	0.064
NPHS1	O60500-1.1	E1052D	Neutral	0.068
NPHS1	O60500-1.1	E1052F	Neutral	0.267
NPHS1	O60500-1.1	E1052G	Neutral	0.08
NPHS1	O60500-1.1	E1052H	Neutral	0.064
NPHS1	O60500-1.1	E1052I	Neutral	0.223
NPHS1	O60500-1.1	E1052K	Neutral	0.076
NPHS1	O60500-1.1	E1052L	Neutral	0.197
NPHS1	O60500-1.1	E1052M	Neutral	0.154
NPHS1	O60500-1.1	E1052N	Neutral	0.025
NPHS1	O60500-1.1	E1052P	Neutral	0.122
NPHS1	O60500-1.1	E1052Q	Neutral	0.076
NPHS1	O60500-1.1	E1052R	Neutral	0.071
NPHS1	O60500-1.1	E1052S	Neutral	0.092
NPHS1	O60500-1.1	E1052T	Neutral	0.061
NPHS1	O60500-1.1	E1052V	Neutral	0.121
NPHS1	O60500-1.1	E1052W	Pathogenic	0.583
NPHS1	O60500-1.1	E1052Y	Neutral	0.154
NPHS1	O60500-1.1	P1053A	Neutral	0.002
NPHS1	O60500-1.1	P1053C	Neutral	0.0
NPHS1	O60500-1.1	P1053D	Neutral	0.006
NPHS1	O60500-1.1	P1053E	Neutral	0.008
NPHS1	O60500-1.1	P1053F	Neutral	0.003
NPHS1	O60500-1.1	P1053G	Neutral	0.004
NPHS1	O60500-1.1	P1053H	Neutral	0.002
NPHS1	O60500-1.1	P1053I	Neutral	0.003
NPHS1	O60500-1.1	P1053K	Neutral	0.024
NPHS1	O60500-1.1	P1053L	Neutral	0.003
NPHS1	O60500-1.1	P1053M	Neutral	0.002
NPHS1	O60500-1.1	P1053N	Neutral	0.004
NPHS1	O60500-1.1	P1053Q	Neutral	0.005
NPHS1	O60500-1.1	P1053R	Neutral	0.023
NPHS1	O60500-1.1	P1053S	Neutral	0.003
NPHS1	O60500-1.1	P1053T	Neutral	0.001
NPHS1	O60500-1.1	P1053V	Neutral	0.001
NPHS1	O60500-1.1	P1053W	Neutral	0.011
NPHS1	O60500-1.1	P1053Y	Neutral	0.001
NPHS1	O60500-1.1	P1054A	Neutral	0.276
NPHS1	O60500-1.1	P1054C	Neutral	0.081
NPHS1	O60500-1.1	P1054D	Pathogenic	0.53
NPHS1	O60500-1.1	P1054E	Pathogenic	0.586
NPHS1	O60500-1.1	P1054F	Neutral	0.34
NPHS1	O60500-1.1	P1054G	Neutral	0.388
NPHS1	O60500-1.1	P1054H	Neutral	0.272
NPHS1	O60500-1.1	P1054I	Neutral	0.377
NPHS1	O60500-1.1	P1054K	Pathogenic	0.815
NPHS1	O60500-1.1	P1054L	Neutral	0.342
NPHS1	O60500-1.1	P1054M	Neutral	0.278
NPHS1	O60500-1.1	P1054N	Neutral	0.398
NPHS1	O60500-1.1	P1054Q	Neutral	0.461
NPHS1	O60500-1.1	P1054R	Pathogenic	0.805
NPHS1	O60500-1.1	P1054S	Neutral	0.356
NPHS1	O60500-1.1	P1054T	Neutral	0.204
NPHS1	O60500-1.1	P1054V	Neutral	0.194
NPHS1	O60500-1.1	P1054W	Pathogenic	0.665
NPHS1	O60500-1.1	P1054Y	Neutral	0.205
NPHS1	O60500-1.1	S1055A	Neutral	0.0
NPHS1	O60500-1.1	S1055C	Neutral	0.0
NPHS1	O60500-1.1	S1055D	Neutral	0.0
NPHS1	O60500-1.1	S1055E	Neutral	0.0
NPHS1	O60500-1.1	S1055F	Neutral	0.0
NPHS1	O60500-1.1	S1055G	Neutral	0.0
NPHS1	O60500-1.1	S1055H	Neutral	0.0
NPHS1	O60500-1.1	S1055I	Neutral	0.0
NPHS1	O60500-1.1	S1055K	Neutral	0.0
NPHS1	O60500-1.1	S1055L	Neutral	0.0
NPHS1	O60500-1.1	S1055M	Neutral	0.0
NPHS1	O60500-1.1	S1055N	Neutral	0.0
NPHS1	O60500-1.1	S1055P	Neutral	0.0
NPHS1	O60500-1.1	S1055Q	Neutral	0.0
NPHS1	O60500-1.1	S1055R	Neutral	0.0
NPHS1	O60500-1.1	S1055T	Neutral	0.0
NPHS1	O60500-1.1	S1055V	Neutral	0.0
NPHS1	O60500-1.1	S1055W	Neutral	0.001
NPHS1	O60500-1.1	S1055Y	Neutral	0.0
NPHS1	O60500-1.1	G1056A	Neutral	0.002
NPHS1	O60500-1.1	G1056C	Neutral	0.003
NPHS1	O60500-1.1	G1056D	Neutral	0.005
NPHS1	O60500-1.1	G1056E	Neutral	0.004
NPHS1	O60500-1.1	G1056F	Neutral	0.027
NPHS1	O60500-1.1	G1056H	Neutral	0.002
NPHS1	O60500-1.1	G1056I	Neutral	0.014
NPHS1	O60500-1.1	G1056K	Neutral	0.012
NPHS1	O60500-1.1	G1056L	Neutral	0.012
NPHS1	O60500-1.1	G1056M	Neutral	0.009
NPHS1	O60500-1.1	G1056N	Neutral	0.006
NPHS1	O60500-1.1	G1056P	Neutral	0.003
NPHS1	O60500-1.1	G1056Q	Neutral	0.002
NPHS1	O60500-1.1	G1056R	Neutral	0.017
NPHS1	O60500-1.1	G1056S	Neutral	0.002
NPHS1	O60500-1.1	G1056T	Neutral	0.002
NPHS1	O60500-1.1	G1056V	Neutral	0.006
NPHS1	O60500-1.1	G1056W	Neutral	0.137
NPHS1	O60500-1.1	G1056Y	Neutral	0.009
NPHS1	O60500-1.1	P1057A	Neutral	0.004
NPHS1	O60500-1.1	P1057C	Neutral	0.001
NPHS1	O60500-1.1	P1057D	Neutral	0.012
NPHS1	O60500-1.1	P1057E	Neutral	0.015
NPHS1	O60500-1.1	P1057F	Neutral	0.006
NPHS1	O60500-1.1	P1057G	Neutral	0.007
NPHS1	O60500-1.1	P1057H	Neutral	0.004
NPHS1	O60500-1.1	P1057I	Neutral	0.007
NPHS1	O60500-1.1	P1057K	Neutral	0.046
NPHS1	O60500-1.1	P1057L	Neutral	0.006
NPHS1	O60500-1.1	P1057M	Neutral	0.004
NPHS1	O60500-1.1	P1057N	Neutral	0.007
NPHS1	O60500-1.1	P1057Q	Neutral	0.009
NPHS1	O60500-1.1	P1057R	Neutral	0.043
NPHS1	O60500-1.1	P1057S	Neutral	0.006
NPHS1	O60500-1.1	P1057T	Neutral	0.003
NPHS1	O60500-1.1	P1057V	Neutral	0.003
NPHS1	O60500-1.1	P1057W	Neutral	0.021
NPHS1	O60500-1.1	P1057Y	Neutral	0.003
NPHS1	O60500-1.1	S1058A	Neutral	0.001
NPHS1	O60500-1.1	S1058C	Neutral	0.002
NPHS1	O60500-1.1	S1058D	Neutral	0.002
NPHS1	O60500-1.1	S1058E	Neutral	0.002
NPHS1	O60500-1.1	S1058F	Neutral	0.011
NPHS1	O60500-1.1	S1058G	Neutral	0.001
NPHS1	O60500-1.1	S1058H	Neutral	0.001
NPHS1	O60500-1.1	S1058I	Neutral	0.008
NPHS1	O60500-1.1	S1058K	Neutral	0.006
NPHS1	O60500-1.1	S1058L	Neutral	0.007
NPHS1	O60500-1.1	S1058M	Neutral	0.005
NPHS1	O60500-1.1	S1058N	Neutral	0.002
NPHS1	O60500-1.1	S1058P	Neutral	0.001
NPHS1	O60500-1.1	S1058Q	Neutral	0.001
NPHS1	O60500-1.1	S1058R	Neutral	0.006
NPHS1	O60500-1.1	S1058T	Neutral	0.001
NPHS1	O60500-1.1	S1058V	Neutral	0.002
NPHS1	O60500-1.1	S1058W	Neutral	0.027
NPHS1	O60500-1.1	S1058Y	Neutral	0.004
NPHS1	O60500-1.1	G1059A	Neutral	0.0
NPHS1	O60500-1.1	G1059C	Neutral	0.0
NPHS1	O60500-1.1	G1059D	Neutral	0.0
NPHS1	O60500-1.1	G1059E	Neutral	0.0
NPHS1	O60500-1.1	G1059F	Neutral	0.002
NPHS1	O60500-1.1	G1059H	Neutral	0.0
NPHS1	O60500-1.1	G1059I	Neutral	0.001
NPHS1	O60500-1.1	G1059K	Neutral	0.001
NPHS1	O60500-1.1	G1059L	Neutral	0.001
NPHS1	O60500-1.1	G1059M	Neutral	0.001
NPHS1	O60500-1.1	G1059N	Neutral	0.001
NPHS1	O60500-1.1	G1059P	Neutral	0.0
NPHS1	O60500-1.1	G1059Q	Neutral	0.0
NPHS1	O60500-1.1	G1059R	Neutral	0.002
NPHS1	O60500-1.1	G1059S	Neutral	0.0
NPHS1	O60500-1.1	G1059T	Neutral	0.0
NPHS1	O60500-1.1	G1059V	Neutral	0.001
NPHS1	O60500-1.1	G1059W	Neutral	0.014
NPHS1	O60500-1.1	G1059Y	Neutral	0.001
NPHS1	O60500-1.1	L1060A	Neutral	0.01
NPHS1	O60500-1.1	L1060C	Neutral	0.002
NPHS1	O60500-1.1	L1060D	Neutral	0.009
NPHS1	O60500-1.1	L1060E	Neutral	0.007
NPHS1	O60500-1.1	L1060F	Neutral	0.001
NPHS1	O60500-1.1	L1060G	Neutral	0.008
NPHS1	O60500-1.1	L1060H	Neutral	0.002
NPHS1	O60500-1.1	L1060I	Neutral	0.001
NPHS1	O60500-1.1	L1060K	Neutral	0.016
NPHS1	O60500-1.1	L1060M	Neutral	0.002
NPHS1	O60500-1.1	L1060N	Neutral	0.009
NPHS1	O60500-1.1	L1060P	Neutral	0.001
NPHS1	O60500-1.1	L1060Q	Neutral	0.005
NPHS1	O60500-1.1	L1060R	Neutral	0.022
NPHS1	O60500-1.1	L1060S	Neutral	0.01
NPHS1	O60500-1.1	L1060T	Neutral	0.006
NPHS1	O60500-1.1	L1060V	Neutral	0.002
NPHS1	O60500-1.1	L1060W	Neutral	0.001
NPHS1	O60500-1.1	L1060Y	Neutral	0.002
NPHS1	O60500-1.1	P1061A	Neutral	0.023
NPHS1	O60500-1.1	P1061C	Neutral	0.005
NPHS1	O60500-1.1	P1061D	Neutral	0.065
NPHS1	O60500-1.1	P1061E	Neutral	0.08
NPHS1	O60500-1.1	P1061F	Neutral	0.031
NPHS1	O60500-1.1	P1061G	Neutral	0.038
NPHS1	O60500-1.1	P1061H	Neutral	0.023
NPHS1	O60500-1.1	P1061I	Neutral	0.036
NPHS1	O60500-1.1	P1061K	Neutral	0.214
NPHS1	O60500-1.1	P1061L	Neutral	0.031
NPHS1	O60500-1.1	P1061M	Neutral	0.023
NPHS1	O60500-1.1	P1061N	Neutral	0.039
NPHS1	O60500-1.1	P1061Q	Neutral	0.05
NPHS1	O60500-1.1	P1061R	Neutral	0.203
NPHS1	O60500-1.1	P1061S	Neutral	0.033
NPHS1	O60500-1.1	P1061T	Neutral	0.016
NPHS1	O60500-1.1	P1061V	Neutral	0.015
NPHS1	O60500-1.1	P1061W	Neutral	0.109
NPHS1	O60500-1.1	P1061Y	Neutral	0.016
NPHS1	O60500-1.1	L1062A	Neutral	0.012
NPHS1	O60500-1.1	L1062C	Neutral	0.003
NPHS1	O60500-1.1	L1062D	Neutral	0.01
NPHS1	O60500-1.1	L1062E	Neutral	0.008
NPHS1	O60500-1.1	L1062F	Neutral	0.001
NPHS1	O60500-1.1	L1062G	Neutral	0.009
NPHS1	O60500-1.1	L1062H	Neutral	0.002
NPHS1	O60500-1.1	L1062I	Neutral	0.002
NPHS1	O60500-1.1	L1062K	Neutral	0.018
NPHS1	O60500-1.1	L1062M	Neutral	0.003
NPHS1	O60500-1.1	L1062N	Neutral	0.01
NPHS1	O60500-1.1	L1062P	Neutral	0.002
NPHS1	O60500-1.1	L1062Q	Neutral	0.006
NPHS1	O60500-1.1	L1062R	Neutral	0.025
NPHS1	O60500-1.1	L1062S	Neutral	0.011
NPHS1	O60500-1.1	L1062T	Neutral	0.007
NPHS1	O60500-1.1	L1062V	Neutral	0.003
NPHS1	O60500-1.1	L1062W	Neutral	0.001
NPHS1	O60500-1.1	L1062Y	Neutral	0.002
NPHS1	O60500-1.1	L1063A	Neutral	0.053
NPHS1	O60500-1.1	L1063C	Neutral	0.013
NPHS1	O60500-1.1	L1063D	Neutral	0.045
NPHS1	O60500-1.1	L1063E	Neutral	0.036
NPHS1	O60500-1.1	L1063F	Neutral	0.004
NPHS1	O60500-1.1	L1063G	Neutral	0.04
NPHS1	O60500-1.1	L1063H	Neutral	0.01
NPHS1	O60500-1.1	L1063I	Neutral	0.007
NPHS1	O60500-1.1	L1063K	Neutral	0.08
NPHS1	O60500-1.1	L1063M	Neutral	0.012
NPHS1	O60500-1.1	L1063N	Neutral	0.046
NPHS1	O60500-1.1	L1063P	Neutral	0.008
NPHS1	O60500-1.1	L1063Q	Neutral	0.026
NPHS1	O60500-1.1	L1063R	Neutral	0.107
NPHS1	O60500-1.1	L1063S	Neutral	0.051
NPHS1	O60500-1.1	L1063T	Neutral	0.031
NPHS1	O60500-1.1	L1063V	Neutral	0.013
NPHS1	O60500-1.1	L1063W	Neutral	0.007
NPHS1	O60500-1.1	L1063Y	Neutral	0.008
NPHS1	O60500-1.1	P1064A	Neutral	0.006
NPHS1	O60500-1.1	P1064C	Neutral	0.001
NPHS1	O60500-1.1	P1064D	Neutral	0.017
NPHS1	O60500-1.1	P1064E	Neutral	0.022
NPHS1	O60500-1.1	P1064F	Neutral	0.008
NPHS1	O60500-1.1	P1064G	Neutral	0.01
NPHS1	O60500-1.1	P1064H	Neutral	0.006
NPHS1	O60500-1.1	P1064I	Neutral	0.009
NPHS1	O60500-1.1	P1064K	Neutral	0.064
NPHS1	O60500-1.1	P1064L	Neutral	0.008
NPHS1	O60500-1.1	P1064M	Neutral	0.006
NPHS1	O60500-1.1	P1064N	Neutral	0.01
NPHS1	O60500-1.1	P1064Q	Neutral	0.013
NPHS1	O60500-1.1	P1064R	Neutral	0.06
NPHS1	O60500-1.1	P1064S	Neutral	0.009
NPHS1	O60500-1.1	P1064T	Neutral	0.004
NPHS1	O60500-1.1	P1064V	Neutral	0.004
NPHS1	O60500-1.1	P1064W	Neutral	0.03
NPHS1	O60500-1.1	P1064Y	Neutral	0.004
NPHS1	O60500-1.1	V1065A	Neutral	0.021
NPHS1	O60500-1.1	V1065C	Neutral	0.003
NPHS1	O60500-1.1	V1065D	Neutral	0.018
NPHS1	O60500-1.1	V1065E	Neutral	0.017
NPHS1	O60500-1.1	V1065F	Neutral	0.007
NPHS1	O60500-1.1	V1065G	Neutral	0.016
NPHS1	O60500-1.1	V1065H	Neutral	0.005
NPHS1	O60500-1.1	V1065I	Neutral	0.027
NPHS1	O60500-1.1	V1065K	Neutral	0.052
NPHS1	O60500-1.1	V1065L	Neutral	0.011
NPHS1	O60500-1.1	V1065M	Neutral	0.005
NPHS1	O60500-1.1	V1065N	Neutral	0.012
NPHS1	O60500-1.1	V1065P	Neutral	0.003
NPHS1	O60500-1.1	V1065Q	Neutral	0.011
NPHS1	O60500-1.1	V1065R	Neutral	0.049
NPHS1	O60500-1.1	V1065S	Neutral	0.014
NPHS1	O60500-1.1	V1065T	Neutral	0.012
NPHS1	O60500-1.1	V1065W	Neutral	0.012
NPHS1	O60500-1.1	V1065Y	Neutral	0.005
NPHS1	O60500-1.1	L1066A	Neutral	0.012
NPHS1	O60500-1.1	L1066C	Neutral	0.003
NPHS1	O60500-1.1	L1066D	Neutral	0.01
NPHS1	O60500-1.1	L1066E	Neutral	0.008
NPHS1	O60500-1.1	L1066F	Neutral	0.001
NPHS1	O60500-1.1	L1066G	Neutral	0.009
NPHS1	O60500-1.1	L1066H	Neutral	0.002
NPHS1	O60500-1.1	L1066I	Neutral	0.002
NPHS1	O60500-1.1	L1066K	Neutral	0.019
NPHS1	O60500-1.1	L1066M	Neutral	0.003
NPHS1	O60500-1.1	L1066N	Neutral	0.011
NPHS1	O60500-1.1	L1066P	Neutral	0.002
NPHS1	O60500-1.1	L1066Q	Neutral	0.006
NPHS1	O60500-1.1	L1066R	Neutral	0.026
NPHS1	O60500-1.1	L1066S	Neutral	0.012
NPHS1	O60500-1.1	L1066T	Neutral	0.007
NPHS1	O60500-1.1	L1066V	Neutral	0.003
NPHS1	O60500-1.1	L1066W	Neutral	0.002
NPHS1	O60500-1.1	L1066Y	Neutral	0.002
NPHS1	O60500-1.1	F1067A	Neutral	0.048
NPHS1	O60500-1.1	F1067C	Neutral	0.012
NPHS1	O60500-1.1	F1067D	Neutral	0.087
NPHS1	O60500-1.1	F1067E	Neutral	0.049
NPHS1	O60500-1.1	F1067G	Neutral	0.077
NPHS1	O60500-1.1	F1067H	Neutral	0.028
NPHS1	O60500-1.1	F1067I	Neutral	0.003
NPHS1	O60500-1.1	F1067K	Neutral	0.045
NPHS1	O60500-1.1	F1067L	Neutral	0.004
NPHS1	O60500-1.1	F1067M	Neutral	0.007
NPHS1	O60500-1.1	F1067N	Neutral	0.062
NPHS1	O60500-1.1	F1067P	Neutral	0.007
NPHS1	O60500-1.1	F1067Q	Neutral	0.024
NPHS1	O60500-1.1	F1067R	Neutral	0.061
NPHS1	O60500-1.1	F1067S	Neutral	0.068
NPHS1	O60500-1.1	F1067T	Neutral	0.029
NPHS1	O60500-1.1	F1067V	Neutral	0.008
NPHS1	O60500-1.1	F1067W	Neutral	0.014
NPHS1	O60500-1.1	F1067Y	Neutral	0.031
NPHS1	O60500-1.1	A1068C	Neutral	0.01
NPHS1	O60500-1.1	A1068D	Neutral	0.01
NPHS1	O60500-1.1	A1068E	Neutral	0.018
NPHS1	O60500-1.1	A1068F	Neutral	0.047
NPHS1	O60500-1.1	A1068G	Neutral	0.006
NPHS1	O60500-1.1	A1068H	Neutral	0.005
NPHS1	O60500-1.1	A1068I	Neutral	0.055
NPHS1	O60500-1.1	A1068K	Neutral	0.053
NPHS1	O60500-1.1	A1068L	Neutral	0.048
NPHS1	O60500-1.1	A1068M	Neutral	0.024
NPHS1	O60500-1.1	A1068N	Neutral	0.008
NPHS1	O60500-1.1	A1068P	Neutral	0.005
NPHS1	O60500-1.1	A1068Q	Neutral	0.011
NPHS1	O60500-1.1	A1068R	Neutral	0.073
NPHS1	O60500-1.1	A1068S	Neutral	0.007
NPHS1	O60500-1.1	A1068T	Neutral	0.005
NPHS1	O60500-1.1	A1068V	Neutral	0.023
NPHS1	O60500-1.1	A1068W	Neutral	0.114
NPHS1	O60500-1.1	A1068Y	Neutral	0.016
NPHS1	O60500-1.1	L1069A	Neutral	0.001
NPHS1	O60500-1.1	L1069C	Neutral	0.0
NPHS1	O60500-1.1	L1069D	Neutral	0.001
NPHS1	O60500-1.1	L1069E	Neutral	0.001
NPHS1	O60500-1.1	L1069F	Neutral	0.0
NPHS1	O60500-1.1	L1069G	Neutral	0.001
NPHS1	O60500-1.1	L1069H	Neutral	0.0
NPHS1	O60500-1.1	L1069I	Neutral	0.0
NPHS1	O60500-1.1	L1069K	Neutral	0.001
NPHS1	O60500-1.1	L1069M	Neutral	0.0
NPHS1	O60500-1.1	L1069N	Neutral	0.001
NPHS1	O60500-1.1	L1069P	Neutral	0.0
NPHS1	O60500-1.1	L1069Q	Neutral	0.0
NPHS1	O60500-1.1	L1069R	Neutral	0.002
NPHS1	O60500-1.1	L1069S	Neutral	0.001
NPHS1	O60500-1.1	L1069T	Neutral	0.0
NPHS1	O60500-1.1	L1069V	Neutral	0.0
NPHS1	O60500-1.1	L1069W	Neutral	0.0
NPHS1	O60500-1.1	L1069Y	Neutral	0.0
NPHS1	O60500-1.1	G1070A	Neutral	0.101
NPHS1	O60500-1.1	G1070C	Neutral	0.126
NPHS1	O60500-1.1	G1070D	Neutral	0.209
NPHS1	O60500-1.1	G1070E	Neutral	0.182
NPHS1	O60500-1.1	G1070F	Pathogenic	0.604
NPHS1	O60500-1.1	G1070H	Neutral	0.115
NPHS1	O60500-1.1	G1070I	Neutral	0.447
NPHS1	O60500-1.1	G1070K	Neutral	0.409
NPHS1	O60500-1.1	G1070L	Neutral	0.409
NPHS1	O60500-1.1	G1070M	Neutral	0.339
NPHS1	O60500-1.1	G1070N	Neutral	0.256
NPHS1	O60500-1.1	G1070P	Neutral	0.138
NPHS1	O60500-1.1	G1070Q	Neutral	0.118
NPHS1	O60500-1.1	G1070R	Neutral	0.491
NPHS1	O60500-1.1	G1070S	Neutral	0.079
NPHS1	O60500-1.1	G1070T	Neutral	0.079
NPHS1	O60500-1.1	G1070V	Neutral	0.243
NPHS1	O60500-1.1	G1070W	Pathogenic	0.898
NPHS1	O60500-1.1	G1070Y	Neutral	0.339
NPHS1	O60500-1.1	G1071A	Neutral	0.014
NPHS1	O60500-1.1	G1071C	Neutral	0.018
NPHS1	O60500-1.1	G1071D	Neutral	0.032
NPHS1	O60500-1.1	G1071E	Neutral	0.027
NPHS1	O60500-1.1	G1071F	Neutral	0.159
NPHS1	O60500-1.1	G1071H	Neutral	0.016
NPHS1	O60500-1.1	G1071I	Neutral	0.091
NPHS1	O60500-1.1	G1071K	Neutral	0.079
NPHS1	O60500-1.1	G1071L	Neutral	0.079
NPHS1	O60500-1.1	G1071M	Neutral	0.06
NPHS1	O60500-1.1	G1071N	Neutral	0.041
NPHS1	O60500-1.1	G1071P	Neutral	0.019
NPHS1	O60500-1.1	G1071Q	Neutral	0.016
NPHS1	O60500-1.1	G1071R	Neutral	0.106
NPHS1	O60500-1.1	G1071S	Neutral	0.011
NPHS1	O60500-1.1	G1071T	Neutral	0.011
NPHS1	O60500-1.1	G1071V	Neutral	0.038
NPHS1	O60500-1.1	G1071W	Pathogenic	0.52
NPHS1	O60500-1.1	G1071Y	Neutral	0.06
NPHS1	O60500-1.1	L1072A	Neutral	0.125
NPHS1	O60500-1.1	L1072C	Neutral	0.032
NPHS1	O60500-1.1	L1072D	Neutral	0.109
NPHS1	O60500-1.1	L1072E	Neutral	0.089
NPHS1	O60500-1.1	L1072F	Neutral	0.01
NPHS1	O60500-1.1	L1072G	Neutral	0.097
NPHS1	O60500-1.1	L1072H	Neutral	0.024
NPHS1	O60500-1.1	L1072I	Neutral	0.018
NPHS1	O60500-1.1	L1072K	Neutral	0.183
NPHS1	O60500-1.1	L1072M	Neutral	0.03
NPHS1	O60500-1.1	L1072N	Neutral	0.112
NPHS1	O60500-1.1	L1072P	Neutral	0.02
NPHS1	O60500-1.1	L1072Q	Neutral	0.065
NPHS1	O60500-1.1	L1072R	Neutral	0.237
NPHS1	O60500-1.1	L1072S	Neutral	0.122
NPHS1	O60500-1.1	L1072T	Neutral	0.077
NPHS1	O60500-1.1	L1072V	Neutral	0.032
NPHS1	O60500-1.1	L1072W	Neutral	0.018
NPHS1	O60500-1.1	L1072Y	Neutral	0.021
NPHS1	O60500-1.1	L1073A	Neutral	0.483
NPHS1	O60500-1.1	L1073C	Neutral	0.179
NPHS1	O60500-1.1	L1073D	Neutral	0.443
NPHS1	O60500-1.1	L1073E	Neutral	0.389
NPHS1	O60500-1.1	L1073F	Neutral	0.063
NPHS1	O60500-1.1	L1073G	Neutral	0.411
NPHS1	O60500-1.1	L1073H	Neutral	0.141
NPHS1	O60500-1.1	L1073I	Neutral	0.106
NPHS1	O60500-1.1	L1073K	Pathogenic	0.593
NPHS1	O60500-1.1	L1073M	Neutral	0.169
NPHS1	O60500-1.1	L1073N	Neutral	0.45
NPHS1	O60500-1.1	L1073P	Neutral	0.117
NPHS1	O60500-1.1	L1073Q	Neutral	0.312
NPHS1	O60500-1.1	L1073R	Pathogenic	0.67
NPHS1	O60500-1.1	L1073S	Neutral	0.476
NPHS1	O60500-1.1	L1073T	Neutral	0.353
NPHS1	O60500-1.1	L1073V	Neutral	0.18
NPHS1	O60500-1.1	L1073W	Neutral	0.105
NPHS1	O60500-1.1	L1073Y	Neutral	0.121
NPHS1	O60500-1.1	L1074A	Neutral	0.068
NPHS1	O60500-1.1	L1074C	Neutral	0.017
NPHS1	O60500-1.1	L1074D	Neutral	0.058
NPHS1	O60500-1.1	L1074E	Neutral	0.047
NPHS1	O60500-1.1	L1074F	Neutral	0.005
NPHS1	O60500-1.1	L1074G	Neutral	0.051
NPHS1	O60500-1.1	L1074H	Neutral	0.013
NPHS1	O60500-1.1	L1074I	Neutral	0.009
NPHS1	O60500-1.1	L1074K	Neutral	0.102
NPHS1	O60500-1.1	L1074M	Neutral	0.016
NPHS1	O60500-1.1	L1074N	Neutral	0.06
NPHS1	O60500-1.1	L1074P	Neutral	0.01
NPHS1	O60500-1.1	L1074Q	Neutral	0.034
NPHS1	O60500-1.1	L1074R	Neutral	0.136
NPHS1	O60500-1.1	L1074S	Neutral	0.066
NPHS1	O60500-1.1	L1074T	Neutral	0.041
NPHS1	O60500-1.1	L1074V	Neutral	0.017
NPHS1	O60500-1.1	L1074W	Neutral	0.009
NPHS1	O60500-1.1	L1074Y	Neutral	0.011
NPHS1	O60500-1.1	L1075A	Neutral	0.033
NPHS1	O60500-1.1	L1075C	Neutral	0.008
NPHS1	O60500-1.1	L1075D	Neutral	0.028
NPHS1	O60500-1.1	L1075E	Neutral	0.023
NPHS1	O60500-1.1	L1075F	Neutral	0.002
NPHS1	O60500-1.1	L1075G	Neutral	0.025
NPHS1	O60500-1.1	L1075H	Neutral	0.006
NPHS1	O60500-1.1	L1075I	Neutral	0.004
NPHS1	O60500-1.1	L1075K	Neutral	0.05
NPHS1	O60500-1.1	L1075M	Neutral	0.007
NPHS1	O60500-1.1	L1075N	Neutral	0.029
NPHS1	O60500-1.1	L1075P	Neutral	0.005
NPHS1	O60500-1.1	L1075Q	Neutral	0.016
NPHS1	O60500-1.1	L1075R	Neutral	0.068
NPHS1	O60500-1.1	L1075S	Neutral	0.032
NPHS1	O60500-1.1	L1075T	Neutral	0.019
NPHS1	O60500-1.1	L1075V	Neutral	0.008
NPHS1	O60500-1.1	L1075W	Neutral	0.004
NPHS1	O60500-1.1	L1075Y	Neutral	0.005
NPHS1	O60500-1.1	S1076A	Neutral	0.043
NPHS1	O60500-1.1	S1076C	Neutral	0.061
NPHS1	O60500-1.1	S1076D	Neutral	0.066
NPHS1	O60500-1.1	S1076E	Neutral	0.082
NPHS1	O60500-1.1	S1076F	Neutral	0.315
NPHS1	O60500-1.1	S1076G	Neutral	0.029
NPHS1	O60500-1.1	S1076H	Neutral	0.037
NPHS1	O60500-1.1	S1076I	Neutral	0.266
NPHS1	O60500-1.1	S1076K	Neutral	0.218
NPHS1	O60500-1.1	S1076L	Neutral	0.237
NPHS1	O60500-1.1	S1076M	Neutral	0.187
NPHS1	O60500-1.1	S1076N	Neutral	0.085
NPHS1	O60500-1.1	S1076P	Neutral	0.046
NPHS1	O60500-1.1	S1076Q	Neutral	0.051
NPHS1	O60500-1.1	S1076R	Neutral	0.206
NPHS1	O60500-1.1	S1076T	Neutral	0.055
NPHS1	O60500-1.1	S1076V	Neutral	0.088
NPHS1	O60500-1.1	S1076W	Pathogenic	0.543
NPHS1	O60500-1.1	S1076Y	Neutral	0.134
NPHS1	O60500-1.1	N1077A	Pathogenic	0.945
NPHS1	O60500-1.1	N1077C	Pathogenic	0.953
NPHS1	O60500-1.1	N1077D	Pathogenic	0.915
NPHS1	O60500-1.1	N1077E	Pathogenic	0.878
NPHS1	O60500-1.1	N1077F	Pathogenic	0.993
NPHS1	O60500-1.1	N1077G	Pathogenic	0.974
NPHS1	O60500-1.1	N1077H	Pathogenic	0.974
NPHS1	O60500-1.1	N1077I	Pathogenic	0.991
NPHS1	O60500-1.1	N1077K	Pathogenic	0.957
NPHS1	O60500-1.1	N1077L	Pathogenic	0.989
NPHS1	O60500-1.1	N1077M	Pathogenic	0.985
NPHS1	O60500-1.1	N1077P	Pathogenic	0.949
NPHS1	O60500-1.1	N1077Q	Pathogenic	0.931
NPHS1	O60500-1.1	N1077R	Pathogenic	0.969
NPHS1	O60500-1.1	N1077S	Pathogenic	0.968
NPHS1	O60500-1.1	N1077T	Pathogenic	0.951
NPHS1	O60500-1.1	N1077V	Pathogenic	0.966
NPHS1	O60500-1.1	N1077W	Pathogenic	0.997
NPHS1	O60500-1.1	N1077Y	Pathogenic	0.985
NPHS1	O60500-1.1	A1078C	Neutral	0.202
NPHS1	O60500-1.1	A1078D	Neutral	0.189
NPHS1	O60500-1.1	A1078E	Neutral	0.305
NPHS1	O60500-1.1	A1078F	Pathogenic	0.546
NPHS1	O60500-1.1	A1078G	Neutral	0.128
NPHS1	O60500-1.1	A1078H	Neutral	0.104
NPHS1	O60500-1.1	A1078I	Pathogenic	0.586
NPHS1	O60500-1.1	A1078K	Pathogenic	0.577
NPHS1	O60500-1.1	A1078L	Pathogenic	0.548
NPHS1	O60500-1.1	A1078M	Neutral	0.377
NPHS1	O60500-1.1	A1078N	Neutral	0.17
NPHS1	O60500-1.1	A1078P	Neutral	0.112
NPHS1	O60500-1.1	A1078Q	Neutral	0.209
NPHS1	O60500-1.1	A1078R	Pathogenic	0.655
NPHS1	O60500-1.1	A1078S	Neutral	0.145
NPHS1	O60500-1.1	A1078T	Neutral	0.106
NPHS1	O60500-1.1	A1078V	Neutral	0.36
NPHS1	O60500-1.1	A1078W	Pathogenic	0.757
NPHS1	O60500-1.1	A1078Y	Neutral	0.288
NPHS1	O60500-1.1	S1079A	Neutral	0.073
NPHS1	O60500-1.1	S1079C	Neutral	0.102
NPHS1	O60500-1.1	S1079D	Neutral	0.111
NPHS1	O60500-1.1	S1079E	Neutral	0.136
NPHS1	O60500-1.1	S1079F	Neutral	0.447
NPHS1	O60500-1.1	S1079G	Neutral	0.05
NPHS1	O60500-1.1	S1079H	Neutral	0.064
NPHS1	O60500-1.1	S1079I	Neutral	0.389
NPHS1	O60500-1.1	S1079K	Neutral	0.329
NPHS1	O60500-1.1	S1079L	Neutral	0.353
NPHS1	O60500-1.1	S1079M	Neutral	0.288
NPHS1	O60500-1.1	S1079N	Neutral	0.14
NPHS1	O60500-1.1	S1079P	Neutral	0.078
NPHS1	O60500-1.1	S1079Q	Neutral	0.087
NPHS1	O60500-1.1	S1079R	Neutral	0.313
NPHS1	O60500-1.1	S1079T	Neutral	0.092
NPHS1	O60500-1.1	S1079V	Neutral	0.145
NPHS1	O60500-1.1	S1079W	Pathogenic	0.676
NPHS1	O60500-1.1	S1079Y	Neutral	0.213
NPHS1	O60500-1.1	C1080A	Pathogenic	0.892
NPHS1	O60500-1.1	C1080D	Pathogenic	0.899
NPHS1	O60500-1.1	C1080E	Pathogenic	0.882
NPHS1	O60500-1.1	C1080F	Pathogenic	0.902
NPHS1	O60500-1.1	C1080G	Pathogenic	0.86
NPHS1	O60500-1.1	C1080H	Pathogenic	0.814
NPHS1	O60500-1.1	C1080I	Pathogenic	0.915
NPHS1	O60500-1.1	C1080K	Pathogenic	0.972
NPHS1	O60500-1.1	C1080L	Pathogenic	0.902
NPHS1	O60500-1.1	C1080M	Pathogenic	0.821
NPHS1	O60500-1.1	C1080N	Pathogenic	0.886
NPHS1	O60500-1.1	C1080P	Neutral	0.486
NPHS1	O60500-1.1	C1080Q	Pathogenic	0.871
NPHS1	O60500-1.1	C1080R	Pathogenic	0.98
NPHS1	O60500-1.1	C1080S	Pathogenic	0.889
NPHS1	O60500-1.1	C1080T	Pathogenic	0.818
NPHS1	O60500-1.1	C1080V	Pathogenic	0.742
NPHS1	O60500-1.1	C1080W	Pathogenic	0.972
NPHS1	O60500-1.1	C1080Y	Pathogenic	0.767
NPHS1	O60500-1.1	V1081A	Neutral	0.174
NPHS1	O60500-1.1	V1081C	Neutral	0.032
NPHS1	O60500-1.1	V1081D	Neutral	0.152
NPHS1	O60500-1.1	V1081E	Neutral	0.148
NPHS1	O60500-1.1	V1081F	Neutral	0.066
NPHS1	O60500-1.1	V1081G	Neutral	0.136
NPHS1	O60500-1.1	V1081H	Neutral	0.044
NPHS1	O60500-1.1	V1081I	Neutral	0.217
NPHS1	O60500-1.1	V1081K	Neutral	0.352
NPHS1	O60500-1.1	V1081L	Neutral	0.096
NPHS1	O60500-1.1	V1081M	Neutral	0.05
NPHS1	O60500-1.1	V1081N	Neutral	0.11
NPHS1	O60500-1.1	V1081P	Neutral	0.029
NPHS1	O60500-1.1	V1081Q	Neutral	0.095
NPHS1	O60500-1.1	V1081R	Neutral	0.336
NPHS1	O60500-1.1	V1081S	Neutral	0.121
NPHS1	O60500-1.1	V1081T	Neutral	0.11
NPHS1	O60500-1.1	V1081W	Neutral	0.109
NPHS1	O60500-1.1	V1081Y	Neutral	0.049
NPHS1	O60500-1.1	G1082A	Neutral	0.102
NPHS1	O60500-1.1	G1082C	Neutral	0.128
NPHS1	O60500-1.1	G1082D	Neutral	0.211
NPHS1	O60500-1.1	G1082E	Neutral	0.184
NPHS1	O60500-1.1	G1082F	Pathogenic	0.608
NPHS1	O60500-1.1	G1082H	Neutral	0.116
NPHS1	O60500-1.1	G1082I	Neutral	0.45
NPHS1	O60500-1.1	G1082K	Neutral	0.413
NPHS1	O60500-1.1	G1082L	Neutral	0.413
NPHS1	O60500-1.1	G1082M	Neutral	0.343
NPHS1	O60500-1.1	G1082N	Neutral	0.259
NPHS1	O60500-1.1	G1082P	Neutral	0.14
NPHS1	O60500-1.1	G1082Q	Neutral	0.12
NPHS1	O60500-1.1	G1082R	Neutral	0.495
NPHS1	O60500-1.1	G1082S	Neutral	0.081
NPHS1	O60500-1.1	G1082T	Neutral	0.081
NPHS1	O60500-1.1	G1082V	Neutral	0.246
NPHS1	O60500-1.1	G1082W	Pathogenic	0.899
NPHS1	O60500-1.1	G1082Y	Neutral	0.342
NPHS1	O60500-1.1	G1083A	Neutral	0.246
NPHS1	O60500-1.1	G1083C	Neutral	0.296
NPHS1	O60500-1.1	G1083D	Neutral	0.434
NPHS1	O60500-1.1	G1083E	Neutral	0.393
NPHS1	O60500-1.1	G1083F	Pathogenic	0.816
NPHS1	O60500-1.1	G1083H	Neutral	0.274
NPHS1	O60500-1.1	G1083I	Pathogenic	0.702
NPHS1	O60500-1.1	G1083K	Pathogenic	0.669
NPHS1	O60500-1.1	G1083L	Pathogenic	0.669
NPHS1	O60500-1.1	G1083M	Pathogenic	0.6
NPHS1	O60500-1.1	G1083N	Pathogenic	0.501
NPHS1	O60500-1.1	G1083P	Neutral	0.318
NPHS1	O60500-1.1	G1083Q	Neutral	0.281
NPHS1	O60500-1.1	G1083R	Pathogenic	0.737
NPHS1	O60500-1.1	G1083S	Neutral	0.201
NPHS1	O60500-1.1	G1083T	Neutral	0.201
NPHS1	O60500-1.1	G1083V	Neutral	0.483
NPHS1	O60500-1.1	G1083W	Pathogenic	0.962
NPHS1	O60500-1.1	G1083Y	Pathogenic	0.599
NPHS1	O60500-1.1	V1084A	Neutral	0.008
NPHS1	O60500-1.1	V1084C	Neutral	0.001
NPHS1	O60500-1.1	V1084D	Neutral	0.007
NPHS1	O60500-1.1	V1084E	Neutral	0.007
NPHS1	O60500-1.1	V1084F	Neutral	0.003
NPHS1	O60500-1.1	V1084G	Neutral	0.006
NPHS1	O60500-1.1	V1084H	Neutral	0.002
NPHS1	O60500-1.1	V1084I	Neutral	0.011
NPHS1	O60500-1.1	V1084K	Neutral	0.02
NPHS1	O60500-1.1	V1084L	Neutral	0.004
NPHS1	O60500-1.1	V1084M	Neutral	0.002
NPHS1	O60500-1.1	V1084N	Neutral	0.005
NPHS1	O60500-1.1	V1084P	Neutral	0.001
NPHS1	O60500-1.1	V1084Q	Neutral	0.004
NPHS1	O60500-1.1	V1084R	Neutral	0.019
NPHS1	O60500-1.1	V1084S	Neutral	0.005
NPHS1	O60500-1.1	V1084T	Neutral	0.005
NPHS1	O60500-1.1	V1084W	Neutral	0.005
NPHS1	O60500-1.1	V1084Y	Neutral	0.002
NPHS1	O60500-1.1	L1085A	Neutral	0.274
NPHS1	O60500-1.1	L1085C	Neutral	0.081
NPHS1	O60500-1.1	L1085D	Neutral	0.243
NPHS1	O60500-1.1	L1085E	Neutral	0.204
NPHS1	O60500-1.1	L1085F	Neutral	0.026
NPHS1	O60500-1.1	L1085G	Neutral	0.22
NPHS1	O60500-1.1	L1085H	Neutral	0.062
NPHS1	O60500-1.1	L1085I	Neutral	0.046
NPHS1	O60500-1.1	L1085K	Neutral	0.37
NPHS1	O60500-1.1	L1085M	Neutral	0.076
NPHS1	O60500-1.1	L1085N	Neutral	0.248
NPHS1	O60500-1.1	L1085P	Neutral	0.051
NPHS1	O60500-1.1	L1085Q	Neutral	0.154
NPHS1	O60500-1.1	L1085R	Neutral	0.45
NPHS1	O60500-1.1	L1085S	Neutral	0.268
NPHS1	O60500-1.1	L1085T	Neutral	0.18
NPHS1	O60500-1.1	L1085V	Neutral	0.081
NPHS1	O60500-1.1	L1085W	Neutral	0.045
NPHS1	O60500-1.1	L1085Y	Neutral	0.053
NPHS1	O60500-1.1	W1086A	Pathogenic	0.993
NPHS1	O60500-1.1	W1086C	Pathogenic	0.979
NPHS1	O60500-1.1	W1086D	Pathogenic	0.996
NPHS1	O60500-1.1	W1086E	Pathogenic	0.995
NPHS1	O60500-1.1	W1086F	Pathogenic	0.936
NPHS1	O60500-1.1	W1086G	Pathogenic	0.998
NPHS1	O60500-1.1	W1086H	Pathogenic	0.987
NPHS1	O60500-1.1	W1086I	Pathogenic	0.791
NPHS1	O60500-1.1	W1086K	Pathogenic	0.995
NPHS1	O60500-1.1	W1086L	Pathogenic	0.868
NPHS1	O60500-1.1	W1086M	Pathogenic	0.952
NPHS1	O60500-1.1	W1086N	Pathogenic	0.994
NPHS1	O60500-1.1	W1086P	Pathogenic	0.966
NPHS1	O60500-1.1	W1086Q	Pathogenic	0.993
NPHS1	O60500-1.1	W1086R	Pathogenic	0.993
NPHS1	O60500-1.1	W1086S	Pathogenic	0.995
NPHS1	O60500-1.1	W1086T	Pathogenic	0.992
NPHS1	O60500-1.1	W1086V	Pathogenic	0.934
NPHS1	O60500-1.1	W1086Y	Pathogenic	0.985
NPHS1	O60500-1.1	Q1087A	Neutral	0.126
NPHS1	O60500-1.1	Q1087C	Neutral	0.102
NPHS1	O60500-1.1	Q1087D	Neutral	0.112
NPHS1	O60500-1.1	Q1087E	Neutral	0.131
NPHS1	O60500-1.1	Q1087F	Neutral	0.241
NPHS1	O60500-1.1	Q1087G	Neutral	0.088
NPHS1	O60500-1.1	Q1087H	Neutral	0.057
NPHS1	O60500-1.1	Q1087I	Neutral	0.201
NPHS1	O60500-1.1	Q1087K	Neutral	0.199
NPHS1	O60500-1.1	Q1087L	Neutral	0.243
NPHS1	O60500-1.1	Q1087M	Neutral	0.262
NPHS1	O60500-1.1	Q1087N	Neutral	0.08
NPHS1	O60500-1.1	Q1087P	Neutral	0.134
NPHS1	O60500-1.1	Q1087R	Neutral	0.257
NPHS1	O60500-1.1	Q1087S	Neutral	0.101
NPHS1	O60500-1.1	Q1087T	Neutral	0.068
NPHS1	O60500-1.1	Q1087V	Neutral	0.132
NPHS1	O60500-1.1	Q1087W	Pathogenic	0.647
NPHS1	O60500-1.1	Q1087Y	Neutral	0.192
NPHS1	O60500-1.1	R1088A	Pathogenic	0.883
NPHS1	O60500-1.1	R1088C	Pathogenic	0.855
NPHS1	O60500-1.1	R1088D	Neutral	0.366
NPHS1	O60500-1.1	R1088E	Pathogenic	0.506
NPHS1	O60500-1.1	R1088F	Pathogenic	0.861
NPHS1	O60500-1.1	R1088G	Pathogenic	0.834
NPHS1	O60500-1.1	R1088H	Pathogenic	0.722
NPHS1	O60500-1.1	R1088I	Pathogenic	0.891
NPHS1	O60500-1.1	R1088K	Neutral	0.422
NPHS1	O60500-1.1	R1088L	Pathogenic	0.913
NPHS1	O60500-1.1	R1088M	Pathogenic	0.886
NPHS1	O60500-1.1	R1088N	Pathogenic	0.595
NPHS1	O60500-1.1	R1088P	Pathogenic	0.844
NPHS1	O60500-1.1	R1088Q	Pathogenic	0.716
NPHS1	O60500-1.1	R1088S	Pathogenic	0.797
NPHS1	O60500-1.1	R1088T	Pathogenic	0.791
NPHS1	O60500-1.1	R1088V	Pathogenic	0.843
NPHS1	O60500-1.1	R1088W	Pathogenic	0.928
NPHS1	O60500-1.1	R1088Y	Pathogenic	0.7
NPHS1	O60500-1.1	R1089A	Pathogenic	0.946
NPHS1	O60500-1.1	R1089C	Pathogenic	0.932
NPHS1	O60500-1.1	R1089D	Pathogenic	0.574
NPHS1	O60500-1.1	R1089E	Pathogenic	0.704
NPHS1	O60500-1.1	R1089F	Pathogenic	0.935
NPHS1	O60500-1.1	R1089G	Pathogenic	0.921
NPHS1	O60500-1.1	R1089H	Pathogenic	0.858
NPHS1	O60500-1.1	R1089I	Pathogenic	0.95
NPHS1	O60500-1.1	R1089K	Pathogenic	0.629
NPHS1	O60500-1.1	R1089L	Pathogenic	0.961
NPHS1	O60500-1.1	R1089M	Pathogenic	0.948
NPHS1	O60500-1.1	R1089N	Pathogenic	0.774
NPHS1	O60500-1.1	R1089P	Pathogenic	0.927
NPHS1	O60500-1.1	R1089Q	Pathogenic	0.855
NPHS1	O60500-1.1	R1089S	Pathogenic	0.902
NPHS1	O60500-1.1	R1089T	Pathogenic	0.898
NPHS1	O60500-1.1	R1089V	Pathogenic	0.926
NPHS1	O60500-1.1	R1089W	Pathogenic	0.968
NPHS1	O60500-1.1	R1089Y	Pathogenic	0.844
NPHS1	O60500-1.1	L1090A	Neutral	0.106
NPHS1	O60500-1.1	L1090C	Neutral	0.027
NPHS1	O60500-1.1	L1090D	Neutral	0.092
NPHS1	O60500-1.1	L1090E	Neutral	0.075
NPHS1	O60500-1.1	L1090F	Neutral	0.009
NPHS1	O60500-1.1	L1090G	Neutral	0.082
NPHS1	O60500-1.1	L1090H	Neutral	0.02
NPHS1	O60500-1.1	L1090I	Neutral	0.015
NPHS1	O60500-1.1	L1090K	Neutral	0.157
NPHS1	O60500-1.1	L1090M	Neutral	0.025
NPHS1	O60500-1.1	L1090N	Neutral	0.095
NPHS1	O60500-1.1	L1090P	Neutral	0.017
NPHS1	O60500-1.1	L1090Q	Neutral	0.055
NPHS1	O60500-1.1	L1090R	Neutral	0.205
NPHS1	O60500-1.1	L1090S	Neutral	0.104
NPHS1	O60500-1.1	L1090T	Neutral	0.065
NPHS1	O60500-1.1	L1090V	Neutral	0.027
NPHS1	O60500-1.1	L1090W	Neutral	0.015
NPHS1	O60500-1.1	L1090Y	Neutral	0.017
NPHS1	O60500-1.1	R1091A	Pathogenic	0.54
NPHS1	O60500-1.1	R1091C	Neutral	0.479
NPHS1	O60500-1.1	R1091D	Neutral	0.082
NPHS1	O60500-1.1	R1091E	Neutral	0.137
NPHS1	O60500-1.1	R1091F	Neutral	0.49
NPHS1	O60500-1.1	R1091G	Neutral	0.438
NPHS1	O60500-1.1	R1091H	Neutral	0.288
NPHS1	O60500-1.1	R1091I	Pathogenic	0.56
NPHS1	O60500-1.1	R1091K	Neutral	0.102
NPHS1	O60500-1.1	R1091L	Pathogenic	0.619
NPHS1	O60500-1.1	R1091M	Pathogenic	0.547
NPHS1	O60500-1.1	R1091N	Neutral	0.186
NPHS1	O60500-1.1	R1091P	Neutral	0.457
NPHS1	O60500-1.1	R1091Q	Neutral	0.282
NPHS1	O60500-1.1	R1091S	Neutral	0.379
NPHS1	O60500-1.1	R1091T	Neutral	0.37
NPHS1	O60500-1.1	R1091V	Neutral	0.454
NPHS1	O60500-1.1	R1091W	Pathogenic	0.667
NPHS1	O60500-1.1	R1091Y	Neutral	0.266
NPHS1	O60500-1.1	R1092A	Neutral	0.476
NPHS1	O60500-1.1	R1092C	Neutral	0.416
NPHS1	O60500-1.1	R1092D	Neutral	0.065
NPHS1	O60500-1.1	R1092E	Neutral	0.11
NPHS1	O60500-1.1	R1092F	Neutral	0.426
NPHS1	O60500-1.1	R1092G	Neutral	0.377
NPHS1	O60500-1.1	R1092H	Neutral	0.238
NPHS1	O60500-1.1	R1092I	Neutral	0.496
NPHS1	O60500-1.1	R1092K	Neutral	0.081
NPHS1	O60500-1.1	R1092L	Pathogenic	0.558
NPHS1	O60500-1.1	R1092M	Neutral	0.483
NPHS1	O60500-1.1	R1092N	Neutral	0.15
NPHS1	O60500-1.1	R1092P	Neutral	0.395
NPHS1	O60500-1.1	R1092Q	Neutral	0.233
NPHS1	O60500-1.1	R1092S	Neutral	0.321
NPHS1	O60500-1.1	R1092T	Neutral	0.313
NPHS1	O60500-1.1	R1092V	Neutral	0.392
NPHS1	O60500-1.1	R1092W	Pathogenic	0.608
NPHS1	O60500-1.1	R1092Y	Neutral	0.219
NPHS1	O60500-1.1	L1093A	Neutral	0.136
NPHS1	O60500-1.1	L1093C	Neutral	0.035
NPHS1	O60500-1.1	L1093D	Neutral	0.118
NPHS1	O60500-1.1	L1093E	Neutral	0.096
NPHS1	O60500-1.1	L1093F	Neutral	0.011
NPHS1	O60500-1.1	L1093G	Neutral	0.105
NPHS1	O60500-1.1	L1093H	Neutral	0.027
NPHS1	O60500-1.1	L1093I	Neutral	0.019
NPHS1	O60500-1.1	L1093K	Neutral	0.197
NPHS1	O60500-1.1	L1093M	Neutral	0.033
NPHS1	O60500-1.1	L1093N	Neutral	0.121
NPHS1	O60500-1.1	L1093P	Neutral	0.022
NPHS1	O60500-1.1	L1093Q	Neutral	0.071
NPHS1	O60500-1.1	L1093R	Neutral	0.254
NPHS1	O60500-1.1	L1093S	Neutral	0.132
NPHS1	O60500-1.1	L1093T	Neutral	0.084
NPHS1	O60500-1.1	L1093V	Neutral	0.035
NPHS1	O60500-1.1	L1093W	Neutral	0.019
NPHS1	O60500-1.1	L1093Y	Neutral	0.023
NPHS1	O60500-1.1	A1094C	Neutral	0.398
NPHS1	O60500-1.1	A1094D	Neutral	0.378
NPHS1	O60500-1.1	A1094E	Pathogenic	0.533
NPHS1	O60500-1.1	A1094F	Pathogenic	0.758
NPHS1	O60500-1.1	A1094G	Neutral	0.277
NPHS1	O60500-1.1	A1094H	Neutral	0.231
NPHS1	O60500-1.1	A1094I	Pathogenic	0.787
NPHS1	O60500-1.1	A1094K	Pathogenic	0.781
NPHS1	O60500-1.1	A1094L	Pathogenic	0.76
NPHS1	O60500-1.1	A1094M	Pathogenic	0.612
NPHS1	O60500-1.1	A1094N	Neutral	0.348
NPHS1	O60500-1.1	A1094P	Neutral	0.247
NPHS1	O60500-1.1	A1094Q	Neutral	0.408
NPHS1	O60500-1.1	A1094R	Pathogenic	0.832
NPHS1	O60500-1.1	A1094S	Neutral	0.307
NPHS1	O60500-1.1	A1094T	Neutral	0.236
NPHS1	O60500-1.1	A1094V	Pathogenic	0.595
NPHS1	O60500-1.1	A1094W	Pathogenic	0.89
NPHS1	O60500-1.1	A1094Y	Pathogenic	0.513
NPHS1	O60500-1.1	E1095A	Pathogenic	0.551
NPHS1	O60500-1.1	E1095C	Neutral	0.392
NPHS1	O60500-1.1	E1095D	Neutral	0.407
NPHS1	O60500-1.1	E1095F	Pathogenic	0.774
NPHS1	O60500-1.1	E1095G	Neutral	0.449
NPHS1	O60500-1.1	E1095H	Neutral	0.392
NPHS1	O60500-1.1	E1095I	Pathogenic	0.73
NPHS1	O60500-1.1	E1095K	Neutral	0.436
NPHS1	O60500-1.1	E1095L	Pathogenic	0.698
NPHS1	O60500-1.1	E1095M	Pathogenic	0.632
NPHS1	O60500-1.1	E1095N	Neutral	0.192
NPHS1	O60500-1.1	E1095P	Pathogenic	0.567
NPHS1	O60500-1.1	E1095Q	Neutral	0.436
NPHS1	O60500-1.1	E1095R	Neutral	0.418
NPHS1	O60500-1.1	E1095S	Neutral	0.487
NPHS1	O60500-1.1	E1095T	Neutral	0.381
NPHS1	O60500-1.1	E1095V	Pathogenic	0.564
NPHS1	O60500-1.1	E1095W	Pathogenic	0.93
NPHS1	O60500-1.1	E1095Y	Pathogenic	0.632
NPHS1	O60500-1.1	G1096A	Neutral	0.398
NPHS1	O60500-1.1	G1096C	Neutral	0.46
NPHS1	O60500-1.1	G1096D	Pathogenic	0.609
NPHS1	O60500-1.1	G1096E	Pathogenic	0.567
NPHS1	O60500-1.1	G1096F	Pathogenic	0.9
NPHS1	O60500-1.1	G1096H	Neutral	0.433
NPHS1	O60500-1.1	G1096I	Pathogenic	0.827
NPHS1	O60500-1.1	G1096K	Pathogenic	0.804
NPHS1	O60500-1.1	G1096L	Pathogenic	0.804
NPHS1	O60500-1.1	G1096M	Pathogenic	0.752
NPHS1	O60500-1.1	G1096N	Pathogenic	0.67
NPHS1	O60500-1.1	G1096P	Neutral	0.486
NPHS1	O60500-1.1	G1096Q	Neutral	0.442
NPHS1	O60500-1.1	G1096R	Pathogenic	0.851
NPHS1	O60500-1.1	G1096S	Neutral	0.338
NPHS1	O60500-1.1	G1096T	Neutral	0.338
NPHS1	O60500-1.1	G1096V	Pathogenic	0.655
NPHS1	O60500-1.1	G1096W	Pathogenic	0.981
NPHS1	O60500-1.1	G1096Y	Pathogenic	0.752
NPHS1	O60500-1.1	I1097A	Pathogenic	0.555
NPHS1	O60500-1.1	I1097C	Neutral	0.226
NPHS1	O60500-1.1	I1097D	Pathogenic	0.612
NPHS1	O60500-1.1	I1097E	Neutral	0.459
NPHS1	O60500-1.1	I1097F	Neutral	0.065
NPHS1	O60500-1.1	I1097G	Neutral	0.482
NPHS1	O60500-1.1	I1097H	Neutral	0.179
NPHS1	O60500-1.1	I1097K	Pathogenic	0.566
NPHS1	O60500-1.1	I1097L	Neutral	0.119
NPHS1	O60500-1.1	I1097M	Neutral	0.154
NPHS1	O60500-1.1	I1097N	Pathogenic	0.522
NPHS1	O60500-1.1	I1097P	Neutral	0.15
NPHS1	O60500-1.1	I1097Q	Neutral	0.288
NPHS1	O60500-1.1	I1097R	Pathogenic	0.644
NPHS1	O60500-1.1	I1097S	Pathogenic	0.547
NPHS1	O60500-1.1	I1097T	Neutral	0.421
NPHS1	O60500-1.1	I1097V	Neutral	0.393
NPHS1	O60500-1.1	I1097W	Neutral	0.071
NPHS1	O60500-1.1	I1097Y	Neutral	0.155
NPHS1	O60500-1.1	S1098A	Neutral	0.086
NPHS1	O60500-1.1	S1098C	Neutral	0.121
NPHS1	O60500-1.1	S1098D	Neutral	0.131
NPHS1	O60500-1.1	S1098E	Neutral	0.159
NPHS1	O60500-1.1	S1098F	Neutral	0.493
NPHS1	O60500-1.1	S1098G	Neutral	0.059
NPHS1	O60500-1.1	S1098H	Neutral	0.076
NPHS1	O60500-1.1	S1098I	Neutral	0.434
NPHS1	O60500-1.1	S1098K	Neutral	0.371
NPHS1	O60500-1.1	S1098L	Neutral	0.397
NPHS1	O60500-1.1	S1098M	Neutral	0.328
NPHS1	O60500-1.1	S1098N	Neutral	0.164
NPHS1	O60500-1.1	S1098P	Neutral	0.092
NPHS1	O60500-1.1	S1098Q	Neutral	0.102
NPHS1	O60500-1.1	S1098R	Neutral	0.355
NPHS1	O60500-1.1	S1098T	Neutral	0.109
NPHS1	O60500-1.1	S1098V	Neutral	0.17
NPHS1	O60500-1.1	S1098W	Pathogenic	0.715
NPHS1	O60500-1.1	S1098Y	Neutral	0.246
NPHS1	O60500-1.1	E1099A	Neutral	0.272
NPHS1	O60500-1.1	E1099C	Neutral	0.164
NPHS1	O60500-1.1	E1099D	Neutral	0.173
NPHS1	O60500-1.1	E1099F	Pathogenic	0.511
NPHS1	O60500-1.1	E1099G	Neutral	0.199
NPHS1	O60500-1.1	E1099H	Neutral	0.165
NPHS1	O60500-1.1	E1099I	Neutral	0.451
NPHS1	O60500-1.1	E1099K	Neutral	0.191
NPHS1	O60500-1.1	E1099L	Neutral	0.414
NPHS1	O60500-1.1	E1099M	Neutral	0.344
NPHS1	O60500-1.1	E1099N	Neutral	0.068
NPHS1	O60500-1.1	E1099P	Neutral	0.286
NPHS1	O60500-1.1	E1099Q	Neutral	0.191
NPHS1	O60500-1.1	E1099R	Neutral	0.18
NPHS1	O60500-1.1	E1099S	Neutral	0.225
NPHS1	O60500-1.1	E1099T	Neutral	0.158
NPHS1	O60500-1.1	E1099V	Neutral	0.283
NPHS1	O60500-1.1	E1099W	Pathogenic	0.801
NPHS1	O60500-1.1	E1099Y	Neutral	0.343
NPHS1	O60500-1.1	K1100A	Pathogenic	0.934
NPHS1	O60500-1.1	K1100C	Pathogenic	0.917
NPHS1	O60500-1.1	K1100D	Pathogenic	0.617
NPHS1	O60500-1.1	K1100E	Pathogenic	0.74
NPHS1	O60500-1.1	K1100F	Pathogenic	0.92
NPHS1	O60500-1.1	K1100G	Pathogenic	0.904
NPHS1	O60500-1.1	K1100H	Pathogenic	0.765
NPHS1	O60500-1.1	K1100I	Pathogenic	0.939
NPHS1	O60500-1.1	K1100L	Pathogenic	0.951
NPHS1	O60500-1.1	K1100M	Pathogenic	0.936
NPHS1	O60500-1.1	K1100N	Pathogenic	0.733
NPHS1	O60500-1.1	K1100P	Pathogenic	0.938
NPHS1	O60500-1.1	K1100Q	Pathogenic	0.825
NPHS1	O60500-1.1	K1100R	Pathogenic	0.654
NPHS1	O60500-1.1	K1100S	Pathogenic	0.916
NPHS1	O60500-1.1	K1100T	Pathogenic	0.876
NPHS1	O60500-1.1	K1100V	Pathogenic	0.937
NPHS1	O60500-1.1	K1100W	Pathogenic	0.978
NPHS1	O60500-1.1	K1100Y	Pathogenic	0.853
NPHS1	O60500-1.1	T1101A	Neutral	0.077
NPHS1	O60500-1.1	T1101C	Neutral	0.089
NPHS1	O60500-1.1	T1101D	Neutral	0.12
NPHS1	O60500-1.1	T1101E	Neutral	0.135
NPHS1	O60500-1.1	T1101F	Neutral	0.333
NPHS1	O60500-1.1	T1101G	Neutral	0.074
NPHS1	O60500-1.1	T1101H	Neutral	0.039
NPHS1	O60500-1.1	T1101I	Neutral	0.369
NPHS1	O60500-1.1	T1101K	Neutral	0.327
NPHS1	O60500-1.1	T1101L	Neutral	0.335
NPHS1	O60500-1.1	T1101M	Neutral	0.2
NPHS1	O60500-1.1	T1101N	Neutral	0.139
NPHS1	O60500-1.1	T1101P	Neutral	0.057
NPHS1	O60500-1.1	T1101Q	Neutral	0.086
NPHS1	O60500-1.1	T1101R	Neutral	0.403
NPHS1	O60500-1.1	T1101S	Neutral	0.135
NPHS1	O60500-1.1	T1101V	Neutral	0.189
NPHS1	O60500-1.1	T1101W	Pathogenic	0.658
NPHS1	O60500-1.1	T1101Y	Neutral	0.143
NPHS1	O60500-1.1	E1102A	Neutral	0.456
NPHS1	O60500-1.1	E1102C	Neutral	0.305
NPHS1	O60500-1.1	E1102D	Neutral	0.319
NPHS1	O60500-1.1	E1102F	Pathogenic	0.7
NPHS1	O60500-1.1	E1102G	Neutral	0.357
NPHS1	O60500-1.1	E1102H	Neutral	0.306
NPHS1	O60500-1.1	E1102I	Pathogenic	0.648
NPHS1	O60500-1.1	E1102K	Neutral	0.345
NPHS1	O60500-1.1	E1102L	Pathogenic	0.613
NPHS1	O60500-1.1	E1102M	Pathogenic	0.54
NPHS1	O60500-1.1	E1102N	Neutral	0.14
NPHS1	O60500-1.1	E1102P	Neutral	0.473
NPHS1	O60500-1.1	E1102Q	Neutral	0.346
NPHS1	O60500-1.1	E1102R	Neutral	0.33
NPHS1	O60500-1.1	E1102S	Neutral	0.394
NPHS1	O60500-1.1	E1102T	Neutral	0.296
NPHS1	O60500-1.1	E1102V	Neutral	0.47
NPHS1	O60500-1.1	E1102W	Pathogenic	0.9
NPHS1	O60500-1.1	E1102Y	Pathogenic	0.539
NPHS1	O60500-1.1	A1103C	Neutral	0.029
NPHS1	O60500-1.1	A1103D	Neutral	0.027
NPHS1	O60500-1.1	A1103E	Neutral	0.049
NPHS1	O60500-1.1	A1103F	Neutral	0.123
NPHS1	O60500-1.1	A1103G	Neutral	0.017
NPHS1	O60500-1.1	A1103H	Neutral	0.013
NPHS1	O60500-1.1	A1103I	Neutral	0.142
NPHS1	O60500-1.1	A1103K	Neutral	0.138
NPHS1	O60500-1.1	A1103L	Neutral	0.124
NPHS1	O60500-1.1	A1103M	Neutral	0.066
NPHS1	O60500-1.1	A1103N	Neutral	0.023
NPHS1	O60500-1.1	A1103P	Neutral	0.014
NPHS1	O60500-1.1	A1103Q	Neutral	0.03
NPHS1	O60500-1.1	A1103R	Neutral	0.181
NPHS1	O60500-1.1	A1103S	Neutral	0.019
NPHS1	O60500-1.1	A1103T	Neutral	0.014
NPHS1	O60500-1.1	A1103V	Neutral	0.062
NPHS1	O60500-1.1	A1103W	Neutral	0.266
NPHS1	O60500-1.1	A1103Y	Neutral	0.045
NPHS1	O60500-1.1	G1104A	Neutral	0.102
NPHS1	O60500-1.1	G1104C	Neutral	0.128
NPHS1	O60500-1.1	G1104D	Neutral	0.211
NPHS1	O60500-1.1	G1104E	Neutral	0.184
NPHS1	O60500-1.1	G1104F	Pathogenic	0.607
NPHS1	O60500-1.1	G1104H	Neutral	0.116
NPHS1	O60500-1.1	G1104I	Neutral	0.45
NPHS1	O60500-1.1	G1104K	Neutral	0.413
NPHS1	O60500-1.1	G1104L	Neutral	0.412
NPHS1	O60500-1.1	G1104M	Neutral	0.342
NPHS1	O60500-1.1	G1104N	Neutral	0.259
NPHS1	O60500-1.1	G1104P	Neutral	0.139
NPHS1	O60500-1.1	G1104Q	Neutral	0.12
NPHS1	O60500-1.1	G1104R	Neutral	0.494
NPHS1	O60500-1.1	G1104S	Neutral	0.08
NPHS1	O60500-1.1	G1104T	Neutral	0.08
NPHS1	O60500-1.1	G1104V	Neutral	0.245
NPHS1	O60500-1.1	G1104W	Pathogenic	0.899
NPHS1	O60500-1.1	G1104Y	Neutral	0.342
NPHS1	O60500-1.1	S1105A	Neutral	0.127
NPHS1	O60500-1.1	S1105C	Neutral	0.174
NPHS1	O60500-1.1	S1105D	Neutral	0.187
NPHS1	O60500-1.1	S1105E	Neutral	0.225
NPHS1	O60500-1.1	S1105F	Pathogenic	0.599
NPHS1	O60500-1.1	S1105G	Neutral	0.088
NPHS1	O60500-1.1	S1105H	Neutral	0.112
NPHS1	O60500-1.1	S1105I	Pathogenic	0.54
NPHS1	O60500-1.1	S1105K	Neutral	0.475
NPHS1	O60500-1.1	S1105L	Pathogenic	0.502
NPHS1	O60500-1.1	S1105M	Neutral	0.428
NPHS1	O60500-1.1	S1105N	Neutral	0.232
NPHS1	O60500-1.1	S1105P	Neutral	0.135
NPHS1	O60500-1.1	S1105Q	Neutral	0.149
NPHS1	O60500-1.1	S1105R	Neutral	0.458
NPHS1	O60500-1.1	S1105T	Neutral	0.158
NPHS1	O60500-1.1	S1105V	Neutral	0.239
NPHS1	O60500-1.1	S1105W	Pathogenic	0.794
NPHS1	O60500-1.1	S1105Y	Neutral	0.334
NPHS1	O60500-1.1	E1106A	Neutral	0.263
NPHS1	O60500-1.1	E1106C	Neutral	0.158
NPHS1	O60500-1.1	E1106D	Neutral	0.167
NPHS1	O60500-1.1	E1106F	Neutral	0.499
NPHS1	O60500-1.1	E1106G	Neutral	0.192
NPHS1	O60500-1.1	E1106H	Neutral	0.158
NPHS1	O60500-1.1	E1106I	Neutral	0.44
NPHS1	O60500-1.1	E1106K	Neutral	0.184
NPHS1	O60500-1.1	E1106L	Neutral	0.403
NPHS1	O60500-1.1	E1106M	Neutral	0.333
NPHS1	O60500-1.1	E1106N	Neutral	0.065
NPHS1	O60500-1.1	E1106P	Neutral	0.276
NPHS1	O60500-1.1	E1106Q	Neutral	0.184
NPHS1	O60500-1.1	E1106R	Neutral	0.173
NPHS1	O60500-1.1	E1106S	Neutral	0.217
NPHS1	O60500-1.1	E1106T	Neutral	0.152
NPHS1	O60500-1.1	E1106V	Neutral	0.274
NPHS1	O60500-1.1	E1106W	Pathogenic	0.793
NPHS1	O60500-1.1	E1106Y	Neutral	0.333
NPHS1	O60500-1.1	E1107A	Neutral	0.427
NPHS1	O60500-1.1	E1107C	Neutral	0.281
NPHS1	O60500-1.1	E1107D	Neutral	0.294
NPHS1	O60500-1.1	E1107F	Pathogenic	0.675
NPHS1	O60500-1.1	E1107G	Neutral	0.331
NPHS1	O60500-1.1	E1107H	Neutral	0.281
NPHS1	O60500-1.1	E1107I	Pathogenic	0.621
NPHS1	O60500-1.1	E1107K	Neutral	0.319
NPHS1	O60500-1.1	E1107L	Pathogenic	0.584
NPHS1	O60500-1.1	E1107M	Pathogenic	0.51
NPHS1	O60500-1.1	E1107N	Neutral	0.126
NPHS1	O60500-1.1	E1107P	Neutral	0.443
NPHS1	O60500-1.1	E1107Q	Neutral	0.319
NPHS1	O60500-1.1	E1107R	Neutral	0.304
NPHS1	O60500-1.1	E1107S	Neutral	0.366
NPHS1	O60500-1.1	E1107T	Neutral	0.272
NPHS1	O60500-1.1	E1107V	Neutral	0.44
NPHS1	O60500-1.1	E1107W	Pathogenic	0.889
NPHS1	O60500-1.1	E1107Y	Pathogenic	0.51
NPHS1	O60500-1.1	D1108A	Neutral	0.165
NPHS1	O60500-1.1	D1108C	Neutral	0.187
NPHS1	O60500-1.1	D1108E	Neutral	0.172
NPHS1	O60500-1.1	D1108F	Pathogenic	0.658
NPHS1	O60500-1.1	D1108G	Neutral	0.226
NPHS1	O60500-1.1	D1108H	Neutral	0.195
NPHS1	O60500-1.1	D1108I	Pathogenic	0.602
NPHS1	O60500-1.1	D1108K	Neutral	0.116
NPHS1	O60500-1.1	D1108L	Neutral	0.466
NPHS1	O60500-1.1	D1108M	Neutral	0.393
NPHS1	O60500-1.1	D1108N	Neutral	0.097
NPHS1	O60500-1.1	D1108P	Neutral	0.239
NPHS1	O60500-1.1	D1108Q	Neutral	0.163
NPHS1	O60500-1.1	D1108R	Neutral	0.109
NPHS1	O60500-1.1	D1108S	Neutral	0.186
NPHS1	O60500-1.1	D1108T	Neutral	0.139
NPHS1	O60500-1.1	D1108V	Neutral	0.288
NPHS1	O60500-1.1	D1108W	Pathogenic	0.832
NPHS1	O60500-1.1	D1108Y	Neutral	0.392
NPHS1	O60500-1.1	R1109A	Pathogenic	0.819
NPHS1	O60500-1.1	R1109C	Pathogenic	0.78
NPHS1	O60500-1.1	R1109D	Neutral	0.257
NPHS1	O60500-1.1	R1109E	Neutral	0.38
NPHS1	O60500-1.1	R1109F	Pathogenic	0.787
NPHS1	O60500-1.1	R1109G	Pathogenic	0.75
NPHS1	O60500-1.1	R1109H	Pathogenic	0.609
NPHS1	O60500-1.1	R1109I	Pathogenic	0.83
NPHS1	O60500-1.1	R1109K	Neutral	0.304
NPHS1	O60500-1.1	R1109L	Pathogenic	0.862
NPHS1	O60500-1.1	R1109M	Pathogenic	0.823
NPHS1	O60500-1.1	R1109N	Neutral	0.468
NPHS1	O60500-1.1	R1109P	Pathogenic	0.764
NPHS1	O60500-1.1	R1109Q	Pathogenic	0.602
NPHS1	O60500-1.1	R1109S	Pathogenic	0.701
NPHS1	O60500-1.1	R1109T	Pathogenic	0.694
NPHS1	O60500-1.1	R1109V	Pathogenic	0.762
NPHS1	O60500-1.1	R1109W	Pathogenic	0.885
NPHS1	O60500-1.1	R1109Y	Pathogenic	0.582
NPHS1	O60500-1.1	V1110A	Neutral	0.067
NPHS1	O60500-1.1	V1110C	Neutral	0.011
NPHS1	O60500-1.1	V1110D	Neutral	0.058
NPHS1	O60500-1.1	V1110E	Neutral	0.056
NPHS1	O60500-1.1	V1110F	Neutral	0.024
NPHS1	O60500-1.1	V1110G	Neutral	0.051
NPHS1	O60500-1.1	V1110H	Neutral	0.015
NPHS1	O60500-1.1	V1110I	Neutral	0.086
NPHS1	O60500-1.1	V1110K	Neutral	0.156
NPHS1	O60500-1.1	V1110L	Neutral	0.035
NPHS1	O60500-1.1	V1110M	Neutral	0.018
NPHS1	O60500-1.1	V1110N	Neutral	0.041
NPHS1	O60500-1.1	V1110P	Neutral	0.01
NPHS1	O60500-1.1	V1110Q	Neutral	0.035
NPHS1	O60500-1.1	V1110R	Neutral	0.147
NPHS1	O60500-1.1	V1110S	Neutral	0.045
NPHS1	O60500-1.1	V1110T	Neutral	0.04
NPHS1	O60500-1.1	V1110W	Neutral	0.04
NPHS1	O60500-1.1	V1110Y	Neutral	0.017
NPHS1	O60500-1.1	R1111A	Neutral	0.321
NPHS1	O60500-1.1	R1111C	Neutral	0.27
NPHS1	O60500-1.1	R1111D	Neutral	0.035
NPHS1	O60500-1.1	R1111E	Neutral	0.06
NPHS1	O60500-1.1	R1111F	Neutral	0.279
NPHS1	O60500-1.1	R1111G	Neutral	0.239
NPHS1	O60500-1.1	R1111H	Neutral	0.14
NPHS1	O60500-1.1	R1111I	Neutral	0.339
NPHS1	O60500-1.1	R1111K	Neutral	0.044
NPHS1	O60500-1.1	R1111L	Neutral	0.396
NPHS1	O60500-1.1	R1111M	Neutral	0.327
NPHS1	O60500-1.1	R1111N	Neutral	0.084
NPHS1	O60500-1.1	R1111P	Neutral	0.253
NPHS1	O60500-1.1	R1111Q	Neutral	0.136
NPHS1	O60500-1.1	R1111S	Neutral	0.197
NPHS1	O60500-1.1	R1111T	Neutral	0.192
NPHS1	O60500-1.1	R1111V	Neutral	0.251
NPHS1	O60500-1.1	R1111W	Neutral	0.446
NPHS1	O60500-1.1	R1111Y	Neutral	0.127
NPHS1	O60500-1.1	N1112A	Pathogenic	0.833
NPHS1	O60500-1.1	N1112C	Pathogenic	0.854
NPHS1	O60500-1.1	N1112D	Pathogenic	0.757
NPHS1	O60500-1.1	N1112E	Pathogenic	0.675
NPHS1	O60500-1.1	N1112F	Pathogenic	0.975
NPHS1	O60500-1.1	N1112G	Pathogenic	0.917
NPHS1	O60500-1.1	N1112H	Pathogenic	0.915
NPHS1	O60500-1.1	N1112I	Pathogenic	0.968
NPHS1	O60500-1.1	N1112K	Pathogenic	0.866
NPHS1	O60500-1.1	N1112L	Pathogenic	0.963
NPHS1	O60500-1.1	N1112M	Pathogenic	0.951
NPHS1	O60500-1.1	N1112P	Pathogenic	0.842
NPHS1	O60500-1.1	N1112Q	Pathogenic	0.796
NPHS1	O60500-1.1	N1112R	Pathogenic	0.9
NPHS1	O60500-1.1	N1112S	Pathogenic	0.896
NPHS1	O60500-1.1	N1112T	Pathogenic	0.848
NPHS1	O60500-1.1	N1112V	Pathogenic	0.89
NPHS1	O60500-1.1	N1112W	Pathogenic	0.99
NPHS1	O60500-1.1	N1112Y	Pathogenic	0.951
NPHS1	O60500-1.1	E1113A	Neutral	0.156
NPHS1	O60500-1.1	E1113C	Neutral	0.089
NPHS1	O60500-1.1	E1113D	Neutral	0.094
NPHS1	O60500-1.1	E1113F	Neutral	0.341
NPHS1	O60500-1.1	E1113G	Neutral	0.11
NPHS1	O60500-1.1	E1113H	Neutral	0.089
NPHS1	O60500-1.1	E1113I	Neutral	0.29
NPHS1	O60500-1.1	E1113K	Neutral	0.105
NPHS1	O60500-1.1	E1113L	Neutral	0.259
NPHS1	O60500-1.1	E1113M	Neutral	0.206
NPHS1	O60500-1.1	E1113N	Neutral	0.035
NPHS1	O60500-1.1	E1113P	Neutral	0.166
NPHS1	O60500-1.1	E1113Q	Neutral	0.105
NPHS1	O60500-1.1	E1113R	Neutral	0.098
NPHS1	O60500-1.1	E1113S	Neutral	0.126
NPHS1	O60500-1.1	E1113T	Neutral	0.085
NPHS1	O60500-1.1	E1113V	Neutral	0.164
NPHS1	O60500-1.1	E1113W	Pathogenic	0.666
NPHS1	O60500-1.1	E1113Y	Neutral	0.206
NPHS1	O60500-1.1	Y1114A	Pathogenic	0.98
NPHS1	O60500-1.1	Y1114C	Pathogenic	0.925
NPHS1	O60500-1.1	Y1114D	Pathogenic	0.989
NPHS1	O60500-1.1	Y1114E	Pathogenic	0.987
NPHS1	O60500-1.1	Y1114F	Pathogenic	0.99
NPHS1	O60500-1.1	Y1114G	Pathogenic	0.988
NPHS1	O60500-1.1	Y1114H	Pathogenic	0.99
NPHS1	O60500-1.1	Y1114I	Pathogenic	0.962
NPHS1	O60500-1.1	Y1114K	Pathogenic	0.986
NPHS1	O60500-1.1	Y1114L	Pathogenic	0.956
NPHS1	O60500-1.1	Y1114M	Pathogenic	0.915
NPHS1	O60500-1.1	Y1114N	Pathogenic	0.99
NPHS1	O60500-1.1	Y1114P	Pathogenic	0.912
NPHS1	O60500-1.1	Y1114Q	Pathogenic	0.981
NPHS1	O60500-1.1	Y1114R	Pathogenic	0.986
NPHS1	O60500-1.1	Y1114S	Pathogenic	0.986
NPHS1	O60500-1.1	Y1114T	Pathogenic	0.966
NPHS1	O60500-1.1	Y1114V	Pathogenic	0.943
NPHS1	O60500-1.1	Y1114W	Pathogenic	0.995
NPHS1	O60500-1.1	E1115A	Pathogenic	0.78
NPHS1	O60500-1.1	E1115C	Pathogenic	0.651
NPHS1	O60500-1.1	E1115D	Pathogenic	0.665
NPHS1	O60500-1.1	E1115F	Pathogenic	0.908
NPHS1	O60500-1.1	E1115G	Pathogenic	0.702
NPHS1	O60500-1.1	E1115H	Pathogenic	0.651
NPHS1	O60500-1.1	E1115I	Pathogenic	0.886
NPHS1	O60500-1.1	E1115K	Pathogenic	0.691
NPHS1	O60500-1.1	E1115L	Pathogenic	0.87
NPHS1	O60500-1.1	E1115M	Pathogenic	0.832
NPHS1	O60500-1.1	E1115N	Neutral	0.408
NPHS1	O60500-1.1	E1115P	Pathogenic	0.791
NPHS1	O60500-1.1	E1115Q	Pathogenic	0.691
NPHS1	O60500-1.1	E1115R	Pathogenic	0.675
NPHS1	O60500-1.1	E1115S	Pathogenic	0.733
NPHS1	O60500-1.1	E1115T	Pathogenic	0.64
NPHS1	O60500-1.1	E1115V	Pathogenic	0.789
NPHS1	O60500-1.1	E1115W	Pathogenic	0.974
NPHS1	O60500-1.1	E1115Y	Pathogenic	0.832
NPHS1	O60500-1.1	E1116A	Neutral	0.114
NPHS1	O60500-1.1	E1116C	Neutral	0.063
NPHS1	O60500-1.1	E1116D	Neutral	0.067
NPHS1	O60500-1.1	E1116F	Neutral	0.264
NPHS1	O60500-1.1	E1116G	Neutral	0.078
NPHS1	O60500-1.1	E1116H	Neutral	0.063
NPHS1	O60500-1.1	E1116I	Neutral	0.22
NPHS1	O60500-1.1	E1116K	Neutral	0.075
NPHS1	O60500-1.1	E1116L	Neutral	0.195
NPHS1	O60500-1.1	E1116M	Neutral	0.152
NPHS1	O60500-1.1	E1116N	Neutral	0.024
NPHS1	O60500-1.1	E1116P	Neutral	0.121
NPHS1	O60500-1.1	E1116Q	Neutral	0.075
NPHS1	O60500-1.1	E1116R	Neutral	0.07
NPHS1	O60500-1.1	E1116S	Neutral	0.09
NPHS1	O60500-1.1	E1116T	Neutral	0.06
NPHS1	O60500-1.1	E1116V	Neutral	0.119
NPHS1	O60500-1.1	E1116W	Pathogenic	0.58
NPHS1	O60500-1.1	E1116Y	Neutral	0.152
NPHS1	O60500-1.1	S1117A	Neutral	0.127
NPHS1	O60500-1.1	S1117C	Neutral	0.174
NPHS1	O60500-1.1	S1117D	Neutral	0.188
NPHS1	O60500-1.1	S1117E	Neutral	0.225
NPHS1	O60500-1.1	S1117F	Pathogenic	0.599
NPHS1	O60500-1.1	S1117G	Neutral	0.088
NPHS1	O60500-1.1	S1117H	Neutral	0.112
NPHS1	O60500-1.1	S1117I	Pathogenic	0.541
NPHS1	O60500-1.1	S1117K	Neutral	0.475
NPHS1	O60500-1.1	S1117L	Pathogenic	0.502
NPHS1	O60500-1.1	S1117M	Neutral	0.428
NPHS1	O60500-1.1	S1117N	Neutral	0.232
NPHS1	O60500-1.1	S1117P	Neutral	0.135
NPHS1	O60500-1.1	S1117Q	Neutral	0.149
NPHS1	O60500-1.1	S1117R	Neutral	0.458
NPHS1	O60500-1.1	S1117T	Neutral	0.158
NPHS1	O60500-1.1	S1117V	Neutral	0.239
NPHS1	O60500-1.1	S1117W	Pathogenic	0.794
NPHS1	O60500-1.1	S1117Y	Neutral	0.334
NPHS1	O60500-1.1	Q1118A	Neutral	0.388
NPHS1	O60500-1.1	Q1118C	Neutral	0.331
NPHS1	O60500-1.1	Q1118D	Neutral	0.356
NPHS1	O60500-1.1	Q1118E	Neutral	0.398
NPHS1	O60500-1.1	Q1118F	Pathogenic	0.583
NPHS1	O60500-1.1	Q1118G	Neutral	0.296
NPHS1	O60500-1.1	Q1118H	Neutral	0.208
NPHS1	O60500-1.1	Q1118I	Pathogenic	0.524
NPHS1	O60500-1.1	Q1118K	Pathogenic	0.522
NPHS1	O60500-1.1	Q1118L	Pathogenic	0.585
NPHS1	O60500-1.1	Q1118M	Pathogenic	0.609
NPHS1	O60500-1.1	Q1118N	Neutral	0.277
NPHS1	O60500-1.1	Q1118P	Neutral	0.404
NPHS1	O60500-1.1	Q1118R	Pathogenic	0.603
NPHS1	O60500-1.1	Q1118S	Neutral	0.329
NPHS1	O60500-1.1	Q1118T	Neutral	0.241
NPHS1	O60500-1.1	Q1118V	Neutral	0.401
NPHS1	O60500-1.1	Q1118W	Pathogenic	0.889
NPHS1	O60500-1.1	Q1118Y	Pathogenic	0.51
NPHS1	O60500-1.1	W1119A	Pathogenic	0.94
NPHS1	O60500-1.1	W1119C	Pathogenic	0.846
NPHS1	O60500-1.1	W1119D	Pathogenic	0.967
NPHS1	O60500-1.1	W1119E	Pathogenic	0.96
NPHS1	O60500-1.1	W1119F	Pathogenic	0.632
NPHS1	O60500-1.1	W1119G	Pathogenic	0.983
NPHS1	O60500-1.1	W1119H	Pathogenic	0.901
NPHS1	O60500-1.1	W1119I	Neutral	0.306
NPHS1	O60500-1.1	W1119K	Pathogenic	0.956
NPHS1	O60500-1.1	W1119L	Neutral	0.434
NPHS1	O60500-1.1	W1119M	Pathogenic	0.697
NPHS1	O60500-1.1	W1119N	Pathogenic	0.954
NPHS1	O60500-1.1	W1119P	Pathogenic	0.768
NPHS1	O60500-1.1	W1119Q	Pathogenic	0.944
NPHS1	O60500-1.1	W1119R	Pathogenic	0.942
NPHS1	O60500-1.1	W1119S	Pathogenic	0.958
NPHS1	O60500-1.1	W1119T	Pathogenic	0.932
NPHS1	O60500-1.1	W1119V	Pathogenic	0.623
NPHS1	O60500-1.1	W1119Y	Pathogenic	0.884
NPHS1	O60500-1.1	T1120A	Neutral	0.088
NPHS1	O60500-1.1	T1120C	Neutral	0.101
NPHS1	O60500-1.1	T1120D	Neutral	0.135
NPHS1	O60500-1.1	T1120E	Neutral	0.151
NPHS1	O60500-1.1	T1120F	Neutral	0.364
NPHS1	O60500-1.1	T1120G	Neutral	0.084
NPHS1	O60500-1.1	T1120H	Neutral	0.045
NPHS1	O60500-1.1	T1120I	Neutral	0.402
NPHS1	O60500-1.1	T1120K	Neutral	0.358
NPHS1	O60500-1.1	T1120L	Neutral	0.366
NPHS1	O60500-1.1	T1120M	Neutral	0.223
NPHS1	O60500-1.1	T1120N	Neutral	0.156
NPHS1	O60500-1.1	T1120P	Neutral	0.065
NPHS1	O60500-1.1	T1120Q	Neutral	0.097
NPHS1	O60500-1.1	T1120R	Neutral	0.436
NPHS1	O60500-1.1	T1120S	Neutral	0.151
NPHS1	O60500-1.1	T1120V	Neutral	0.211
NPHS1	O60500-1.1	T1120W	Pathogenic	0.688
NPHS1	O60500-1.1	T1120Y	Neutral	0.161
NPHS1	O60500-1.1	G1121A	Neutral	0.196
NPHS1	O60500-1.1	G1121C	Neutral	0.239
NPHS1	O60500-1.1	G1121D	Neutral	0.364
NPHS1	O60500-1.1	G1121E	Neutral	0.326
NPHS1	O60500-1.1	G1121F	Pathogenic	0.769
NPHS1	O60500-1.1	G1121H	Neutral	0.22
NPHS1	O60500-1.1	G1121I	Pathogenic	0.637
NPHS1	O60500-1.1	G1121K	Pathogenic	0.601
NPHS1	O60500-1.1	G1121L	Pathogenic	0.601
NPHS1	O60500-1.1	G1121M	Pathogenic	0.528
NPHS1	O60500-1.1	G1121N	Neutral	0.428
NPHS1	O60500-1.1	G1121P	Neutral	0.258
NPHS1	O60500-1.1	G1121Q	Neutral	0.226
NPHS1	O60500-1.1	G1121R	Pathogenic	0.677
NPHS1	O60500-1.1	G1121S	Neutral	0.158
NPHS1	O60500-1.1	G1121T	Neutral	0.158
NPHS1	O60500-1.1	G1121V	Neutral	0.411
NPHS1	O60500-1.1	G1121W	Pathogenic	0.95
NPHS1	O60500-1.1	G1121Y	Pathogenic	0.527
NPHS1	O60500-1.1	E1122A	Neutral	0.009
NPHS1	O60500-1.1	E1122C	Neutral	0.005
NPHS1	O60500-1.1	E1122D	Neutral	0.005
NPHS1	O60500-1.1	E1122F	Neutral	0.024
NPHS1	O60500-1.1	E1122G	Neutral	0.006
NPHS1	O60500-1.1	E1122H	Neutral	0.005
NPHS1	O60500-1.1	E1122I	Neutral	0.019
NPHS1	O60500-1.1	E1122K	Neutral	0.006
NPHS1	O60500-1.1	E1122L	Neutral	0.016
NPHS1	O60500-1.1	E1122M	Neutral	0.012
NPHS1	O60500-1.1	E1122N	Neutral	0.002
NPHS1	O60500-1.1	E1122P	Neutral	0.009
NPHS1	O60500-1.1	E1122Q	Neutral	0.006
NPHS1	O60500-1.1	E1122R	Neutral	0.005
NPHS1	O60500-1.1	E1122S	Neutral	0.007
NPHS1	O60500-1.1	E1122T	Neutral	0.004
NPHS1	O60500-1.1	E1122V	Neutral	0.009
NPHS1	O60500-1.1	E1122W	Neutral	0.087
NPHS1	O60500-1.1	E1122Y	Neutral	0.012
NPHS1	O60500-1.1	R1123A	Neutral	0.276
NPHS1	O60500-1.1	R1123C	Neutral	0.23
NPHS1	O60500-1.1	R1123D	Neutral	0.028
NPHS1	O60500-1.1	R1123E	Neutral	0.049
NPHS1	O60500-1.1	R1123F	Neutral	0.238
NPHS1	O60500-1.1	R1123G	Neutral	0.202
NPHS1	O60500-1.1	R1123H	Neutral	0.116
NPHS1	O60500-1.1	R1123I	Neutral	0.293
NPHS1	O60500-1.1	R1123K	Neutral	0.036
NPHS1	O60500-1.1	R1123L	Neutral	0.346
NPHS1	O60500-1.1	R1123M	Neutral	0.282
NPHS1	O60500-1.1	R1123N	Neutral	0.069
NPHS1	O60500-1.1	R1123P	Neutral	0.215
NPHS1	O60500-1.1	R1123Q	Neutral	0.113
NPHS1	O60500-1.1	R1123S	Neutral	0.166
NPHS1	O60500-1.1	R1123T	Neutral	0.161
NPHS1	O60500-1.1	R1123V	Neutral	0.213
NPHS1	O60500-1.1	R1123W	Neutral	0.394
NPHS1	O60500-1.1	R1123Y	Neutral	0.105
NPHS1	O60500-1.1	D1124A	Pathogenic	0.579
NPHS1	O60500-1.1	D1124C	Pathogenic	0.616
NPHS1	O60500-1.1	D1124E	Pathogenic	0.591
NPHS1	O60500-1.1	D1124F	Pathogenic	0.931
NPHS1	O60500-1.1	D1124G	Pathogenic	0.67
NPHS1	O60500-1.1	D1124H	Pathogenic	0.629
NPHS1	O60500-1.1	D1124I	Pathogenic	0.913
NPHS1	O60500-1.1	D1124K	Neutral	0.478
NPHS1	O60500-1.1	D1124L	Pathogenic	0.859
NPHS1	O60500-1.1	D1124M	Pathogenic	0.818
NPHS1	O60500-1.1	D1124N	Neutral	0.429
NPHS1	O60500-1.1	D1124P	Pathogenic	0.687
NPHS1	O60500-1.1	D1124Q	Pathogenic	0.576
NPHS1	O60500-1.1	D1124R	Neutral	0.461
NPHS1	O60500-1.1	D1124S	Pathogenic	0.614
NPHS1	O60500-1.1	D1124T	Pathogenic	0.53
NPHS1	O60500-1.1	D1124V	Pathogenic	0.738
NPHS1	O60500-1.1	D1124W	Pathogenic	0.972
NPHS1	O60500-1.1	D1124Y	Pathogenic	0.818
NPHS1	O60500-1.1	T1125A	Neutral	0.074
NPHS1	O60500-1.1	T1125C	Neutral	0.085
NPHS1	O60500-1.1	T1125D	Neutral	0.114
NPHS1	O60500-1.1	T1125E	Neutral	0.129
NPHS1	O60500-1.1	T1125F	Neutral	0.321
NPHS1	O60500-1.1	T1125G	Neutral	0.071
NPHS1	O60500-1.1	T1125H	Neutral	0.038
NPHS1	O60500-1.1	T1125I	Neutral	0.357
NPHS1	O60500-1.1	T1125K	Neutral	0.316
NPHS1	O60500-1.1	T1125L	Neutral	0.323
NPHS1	O60500-1.1	T1125M	Neutral	0.192
NPHS1	O60500-1.1	T1125N	Neutral	0.133
NPHS1	O60500-1.1	T1125P	Neutral	0.054
NPHS1	O60500-1.1	T1125Q	Neutral	0.082
NPHS1	O60500-1.1	T1125R	Neutral	0.39
NPHS1	O60500-1.1	T1125S	Neutral	0.129
NPHS1	O60500-1.1	T1125V	Neutral	0.181
NPHS1	O60500-1.1	T1125W	Pathogenic	0.646
NPHS1	O60500-1.1	T1125Y	Neutral	0.137
NPHS1	O60500-1.1	Q1126A	Neutral	0.059
NPHS1	O60500-1.1	Q1126C	Neutral	0.047
NPHS1	O60500-1.1	Q1126D	Neutral	0.052
NPHS1	O60500-1.1	Q1126E	Neutral	0.062
NPHS1	O60500-1.1	Q1126F	Neutral	0.122
NPHS1	O60500-1.1	Q1126G	Neutral	0.04
NPHS1	O60500-1.1	Q1126H	Neutral	0.025
NPHS1	O60500-1.1	Q1126I	Neutral	0.098
NPHS1	O60500-1.1	Q1126K	Neutral	0.098
NPHS1	O60500-1.1	Q1126L	Neutral	0.123
NPHS1	O60500-1.1	Q1126M	Neutral	0.134
NPHS1	O60500-1.1	Q1126N	Neutral	0.037
NPHS1	O60500-1.1	Q1126P	Neutral	0.063
NPHS1	O60500-1.1	Q1126R	Neutral	0.131
NPHS1	O60500-1.1	Q1126S	Neutral	0.046
NPHS1	O60500-1.1	Q1126T	Neutral	0.031
NPHS1	O60500-1.1	Q1126V	Neutral	0.062
NPHS1	O60500-1.1	Q1126W	Neutral	0.443
NPHS1	O60500-1.1	Q1126Y	Neutral	0.094
NPHS1	O60500-1.1	S1127A	Neutral	0.398
NPHS1	O60500-1.1	S1127C	Neutral	0.489
NPHS1	O60500-1.1	S1127D	Pathogenic	0.512
NPHS1	O60500-1.1	S1127E	Pathogenic	0.569
NPHS1	O60500-1.1	S1127F	Pathogenic	0.871
NPHS1	O60500-1.1	S1127G	Neutral	0.305
NPHS1	O60500-1.1	S1127H	Neutral	0.365
NPHS1	O60500-1.1	S1127I	Pathogenic	0.842
NPHS1	O60500-1.1	S1127K	Pathogenic	0.805
NPHS1	O60500-1.1	S1127L	Pathogenic	0.821
NPHS1	O60500-1.1	S1127M	Pathogenic	0.773
NPHS1	O60500-1.1	S1127N	Pathogenic	0.578
NPHS1	O60500-1.1	S1127P	Neutral	0.415
NPHS1	O60500-1.1	S1127Q	Neutral	0.444
NPHS1	O60500-1.1	S1127R	Pathogenic	0.793
NPHS1	O60500-1.1	S1127T	Neutral	0.46
NPHS1	O60500-1.1	S1127V	Pathogenic	0.588
NPHS1	O60500-1.1	S1127W	Pathogenic	0.946
NPHS1	O60500-1.1	S1127Y	Pathogenic	0.695
NPHS1	O60500-1.1	S1128A	Neutral	0.253
NPHS1	O60500-1.1	S1128C	Neutral	0.329
NPHS1	O60500-1.1	S1128D	Neutral	0.35
NPHS1	O60500-1.1	S1128E	Neutral	0.404
NPHS1	O60500-1.1	S1128F	Pathogenic	0.777
NPHS1	O60500-1.1	S1128G	Neutral	0.184
NPHS1	O60500-1.1	S1128H	Neutral	0.228
NPHS1	O60500-1.1	S1128I	Pathogenic	0.733
NPHS1	O60500-1.1	S1128K	Pathogenic	0.679
NPHS1	O60500-1.1	S1128L	Pathogenic	0.702
NPHS1	O60500-1.1	S1128M	Pathogenic	0.636
NPHS1	O60500-1.1	S1128N	Neutral	0.413
NPHS1	O60500-1.1	S1128P	Neutral	0.267
NPHS1	O60500-1.1	S1128Q	Neutral	0.29
NPHS1	O60500-1.1	S1128R	Pathogenic	0.663
NPHS1	O60500-1.1	S1128T	Neutral	0.304
NPHS1	O60500-1.1	S1128V	Neutral	0.423
NPHS1	O60500-1.1	S1128W	Pathogenic	0.9
NPHS1	O60500-1.1	S1128Y	Pathogenic	0.539
NPHS1	O60500-1.1	T1129A	Neutral	0.035
NPHS1	O60500-1.1	T1129C	Neutral	0.041
NPHS1	O60500-1.1	T1129D	Neutral	0.055
NPHS1	O60500-1.1	T1129E	Neutral	0.063
NPHS1	O60500-1.1	T1129F	Neutral	0.177
NPHS1	O60500-1.1	T1129G	Neutral	0.033
NPHS1	O60500-1.1	T1129H	Neutral	0.017
NPHS1	O60500-1.1	T1129I	Neutral	0.202
NPHS1	O60500-1.1	T1129K	Neutral	0.173
NPHS1	O60500-1.1	T1129L	Neutral	0.178
NPHS1	O60500-1.1	T1129M	Neutral	0.097
NPHS1	O60500-1.1	T1129N	Neutral	0.065
NPHS1	O60500-1.1	T1129P	Neutral	0.025
NPHS1	O60500-1.1	T1129Q	Neutral	0.039
NPHS1	O60500-1.1	T1129R	Neutral	0.226
NPHS1	O60500-1.1	T1129S	Neutral	0.063
NPHS1	O60500-1.1	T1129V	Neutral	0.091
NPHS1	O60500-1.1	T1129W	Neutral	0.453
NPHS1	O60500-1.1	T1129Y	Neutral	0.067
NPHS1	O60500-1.1	V1130A	Neutral	0.276
NPHS1	O60500-1.1	V1130C	Neutral	0.056
NPHS1	O60500-1.1	V1130D	Neutral	0.245
NPHS1	O60500-1.1	V1130E	Neutral	0.239
NPHS1	O60500-1.1	V1130F	Neutral	0.114
NPHS1	O60500-1.1	V1130G	Neutral	0.222
NPHS1	O60500-1.1	V1130H	Neutral	0.076
NPHS1	O60500-1.1	V1130I	Neutral	0.333
NPHS1	O60500-1.1	V1130K	Neutral	0.495
NPHS1	O60500-1.1	V1130L	Neutral	0.162
NPHS1	O60500-1.1	V1130M	Neutral	0.088
NPHS1	O60500-1.1	V1130N	Neutral	0.183
NPHS1	O60500-1.1	V1130P	Neutral	0.051
NPHS1	O60500-1.1	V1130Q	Neutral	0.159
NPHS1	O60500-1.1	V1130R	Neutral	0.477
NPHS1	O60500-1.1	V1130S	Neutral	0.199
NPHS1	O60500-1.1	V1130T	Neutral	0.182
NPHS1	O60500-1.1	V1130W	Neutral	0.182
NPHS1	O60500-1.1	V1130Y	Neutral	0.085
NPHS1	O60500-1.1	S1131A	Neutral	0.243
NPHS1	O60500-1.1	S1131C	Neutral	0.318
NPHS1	O60500-1.1	S1131D	Neutral	0.338
NPHS1	O60500-1.1	S1131E	Neutral	0.391
NPHS1	O60500-1.1	S1131F	Pathogenic	0.767
NPHS1	O60500-1.1	S1131G	Neutral	0.176
NPHS1	O60500-1.1	S1131H	Neutral	0.219
NPHS1	O60500-1.1	S1131I	Pathogenic	0.722
NPHS1	O60500-1.1	S1131K	Pathogenic	0.667
NPHS1	O60500-1.1	S1131L	Pathogenic	0.691
NPHS1	O60500-1.1	S1131M	Pathogenic	0.623
NPHS1	O60500-1.1	S1131N	Neutral	0.4
NPHS1	O60500-1.1	S1131P	Neutral	0.257
NPHS1	O60500-1.1	S1131Q	Neutral	0.279
NPHS1	O60500-1.1	S1131R	Pathogenic	0.651
NPHS1	O60500-1.1	S1131T	Neutral	0.293
NPHS1	O60500-1.1	S1131V	Neutral	0.409
NPHS1	O60500-1.1	S1131W	Pathogenic	0.895
NPHS1	O60500-1.1	S1131Y	Pathogenic	0.526
NPHS1	O60500-1.1	T1132A	Neutral	0.271
NPHS1	O60500-1.1	T1132C	Neutral	0.303
NPHS1	O60500-1.1	T1132D	Neutral	0.376
NPHS1	O60500-1.1	T1132E	Neutral	0.408
NPHS1	O60500-1.1	T1132F	Pathogenic	0.689
NPHS1	O60500-1.1	T1132G	Neutral	0.262
NPHS1	O60500-1.1	T1132H	Neutral	0.154
NPHS1	O60500-1.1	T1132I	Pathogenic	0.722
NPHS1	O60500-1.1	T1132K	Pathogenic	0.683
NPHS1	O60500-1.1	T1132L	Pathogenic	0.69
NPHS1	O60500-1.1	T1132M	Pathogenic	0.526
NPHS1	O60500-1.1	T1132N	Neutral	0.418
NPHS1	O60500-1.1	T1132P	Neutral	0.211
NPHS1	O60500-1.1	T1132Q	Neutral	0.294
NPHS1	O60500-1.1	T1132R	Pathogenic	0.75
NPHS1	O60500-1.1	T1132S	Neutral	0.408
NPHS1	O60500-1.1	T1132V	Pathogenic	0.508
NPHS1	O60500-1.1	T1132W	Pathogenic	0.895
NPHS1	O60500-1.1	T1132Y	Neutral	0.426
NPHS1	O60500-1.1	T1133A	Neutral	0.006
NPHS1	O60500-1.1	T1133C	Neutral	0.007
NPHS1	O60500-1.1	T1133D	Neutral	0.009
NPHS1	O60500-1.1	T1133E	Neutral	0.011
NPHS1	O60500-1.1	T1133F	Neutral	0.033
NPHS1	O60500-1.1	T1133G	Neutral	0.006
NPHS1	O60500-1.1	T1133H	Neutral	0.003
NPHS1	O60500-1.1	T1133I	Neutral	0.039
NPHS1	O60500-1.1	T1133K	Neutral	0.033
NPHS1	O60500-1.1	T1133L	Neutral	0.034
NPHS1	O60500-1.1	T1133M	Neutral	0.017
NPHS1	O60500-1.1	T1133N	Neutral	0.011
NPHS1	O60500-1.1	T1133P	Neutral	0.004
NPHS1	O60500-1.1	T1133Q	Neutral	0.006
NPHS1	O60500-1.1	T1133R	Neutral	0.045
NPHS1	O60500-1.1	T1133S	Neutral	0.011
NPHS1	O60500-1.1	T1133V	Neutral	0.016
NPHS1	O60500-1.1	T1133W	Neutral	0.117
NPHS1	O60500-1.1	T1133Y	Neutral	0.011
NPHS1	O60500-1.1	E1134A	Neutral	0.204
NPHS1	O60500-1.1	E1134C	Neutral	0.119
NPHS1	O60500-1.1	E1134D	Neutral	0.126
NPHS1	O60500-1.1	E1134F	Neutral	0.417
NPHS1	O60500-1.1	E1134G	Neutral	0.146
NPHS1	O60500-1.1	E1134H	Neutral	0.119
NPHS1	O60500-1.1	E1134I	Neutral	0.361
NPHS1	O60500-1.1	E1134K	Neutral	0.139
NPHS1	O60500-1.1	E1134L	Neutral	0.326
NPHS1	O60500-1.1	E1134M	Neutral	0.264
NPHS1	O60500-1.1	E1134N	Neutral	0.047
NPHS1	O60500-1.1	E1134P	Neutral	0.215
NPHS1	O60500-1.1	E1134Q	Neutral	0.139
NPHS1	O60500-1.1	E1134R	Neutral	0.131
NPHS1	O60500-1.1	E1134S	Neutral	0.166
NPHS1	O60500-1.1	E1134T	Neutral	0.114
NPHS1	O60500-1.1	E1134V	Neutral	0.213
NPHS1	O60500-1.1	E1134W	Pathogenic	0.734
NPHS1	O60500-1.1	E1134Y	Neutral	0.264
NPHS1	O60500-1.1	A1135C	Neutral	0.001
NPHS1	O60500-1.1	A1135D	Neutral	0.001
NPHS1	O60500-1.1	A1135E	Neutral	0.002
NPHS1	O60500-1.1	A1135F	Neutral	0.005
NPHS1	O60500-1.1	A1135G	Neutral	0.001
NPHS1	O60500-1.1	A1135H	Neutral	0.0
NPHS1	O60500-1.1	A1135I	Neutral	0.006
NPHS1	O60500-1.1	A1135K	Neutral	0.006
NPHS1	O60500-1.1	A1135L	Neutral	0.005
NPHS1	O60500-1.1	A1135M	Neutral	0.002
NPHS1	O60500-1.1	A1135N	Neutral	0.001
NPHS1	O60500-1.1	A1135P	Neutral	0.001
NPHS1	O60500-1.1	A1135Q	Neutral	0.001
NPHS1	O60500-1.1	A1135R	Neutral	0.008
NPHS1	O60500-1.1	A1135S	Neutral	0.001
NPHS1	O60500-1.1	A1135T	Neutral	0.0
NPHS1	O60500-1.1	A1135V	Neutral	0.002
NPHS1	O60500-1.1	A1135W	Neutral	0.013
NPHS1	O60500-1.1	A1135Y	Neutral	0.002
NPHS1	O60500-1.1	E1136A	Neutral	0.241
NPHS1	O60500-1.1	E1136C	Neutral	0.143
NPHS1	O60500-1.1	E1136D	Neutral	0.151
NPHS1	O60500-1.1	E1136F	Neutral	0.469
NPHS1	O60500-1.1	E1136G	Neutral	0.174
NPHS1	O60500-1.1	E1136H	Neutral	0.143
NPHS1	O60500-1.1	E1136I	Neutral	0.411
NPHS1	O60500-1.1	E1136K	Neutral	0.166
NPHS1	O60500-1.1	E1136L	Neutral	0.374
NPHS1	O60500-1.1	E1136M	Neutral	0.307
NPHS1	O60500-1.1	E1136N	Neutral	0.058
NPHS1	O60500-1.1	E1136P	Neutral	0.253
NPHS1	O60500-1.1	E1136Q	Neutral	0.167
NPHS1	O60500-1.1	E1136R	Neutral	0.157
NPHS1	O60500-1.1	E1136S	Neutral	0.197
NPHS1	O60500-1.1	E1136T	Neutral	0.137
NPHS1	O60500-1.1	E1136V	Neutral	0.251
NPHS1	O60500-1.1	E1136W	Pathogenic	0.773
NPHS1	O60500-1.1	E1136Y	Neutral	0.307
NPHS1	O60500-1.1	P1137A	Neutral	0.145
NPHS1	O60500-1.1	P1137C	Neutral	0.038
NPHS1	O60500-1.1	P1137D	Neutral	0.333
NPHS1	O60500-1.1	P1137E	Neutral	0.386
NPHS1	O60500-1.1	P1137F	Neutral	0.186
NPHS1	O60500-1.1	P1137G	Neutral	0.219
NPHS1	O60500-1.1	P1137H	Neutral	0.142
NPHS1	O60500-1.1	P1137I	Neutral	0.212
NPHS1	O60500-1.1	P1137K	Pathogenic	0.662
NPHS1	O60500-1.1	P1137L	Neutral	0.187
NPHS1	O60500-1.1	P1137M	Neutral	0.146
NPHS1	O60500-1.1	P1137N	Neutral	0.227
NPHS1	O60500-1.1	P1137Q	Neutral	0.275
NPHS1	O60500-1.1	P1137R	Pathogenic	0.646
NPHS1	O60500-1.1	P1137S	Neutral	0.197
NPHS1	O60500-1.1	P1137T	Neutral	0.102
NPHS1	O60500-1.1	P1137V	Neutral	0.097
NPHS1	O60500-1.1	P1137W	Neutral	0.468
NPHS1	O60500-1.1	P1137Y	Neutral	0.103
NPHS1	O60500-1.1	Y1138A	Pathogenic	0.85
NPHS1	O60500-1.1	Y1138C	Pathogenic	0.587
NPHS1	O60500-1.1	Y1138D	Pathogenic	0.915
NPHS1	O60500-1.1	Y1138E	Pathogenic	0.896
NPHS1	O60500-1.1	Y1138F	Pathogenic	0.916
NPHS1	O60500-1.1	Y1138G	Pathogenic	0.904
NPHS1	O60500-1.1	Y1138H	Pathogenic	0.916
NPHS1	O60500-1.1	Y1138I	Pathogenic	0.746
NPHS1	O60500-1.1	Y1138K	Pathogenic	0.887
NPHS1	O60500-1.1	Y1138L	Pathogenic	0.715
NPHS1	O60500-1.1	Y1138M	Pathogenic	0.556
NPHS1	O60500-1.1	Y1138N	Pathogenic	0.917
NPHS1	O60500-1.1	Y1138P	Pathogenic	0.546
NPHS1	O60500-1.1	Y1138Q	Pathogenic	0.86
NPHS1	O60500-1.1	Y1138R	Pathogenic	0.892
NPHS1	O60500-1.1	Y1138S	Pathogenic	0.892
NPHS1	O60500-1.1	Y1138T	Pathogenic	0.769
NPHS1	O60500-1.1	Y1138V	Pathogenic	0.657
NPHS1	O60500-1.1	Y1138W	Pathogenic	0.955
NPHS1	O60500-1.1	Y1139A	Pathogenic	0.992
NPHS1	O60500-1.1	Y1139C	Pathogenic	0.968
NPHS1	O60500-1.1	Y1139D	Pathogenic	0.996
NPHS1	O60500-1.1	Y1139E	Pathogenic	0.995
NPHS1	O60500-1.1	Y1139F	Pathogenic	0.996
NPHS1	O60500-1.1	Y1139G	Pathogenic	0.995
NPHS1	O60500-1.1	Y1139H	Pathogenic	0.996
NPHS1	O60500-1.1	Y1139I	Pathogenic	0.984
NPHS1	O60500-1.1	Y1139K	Pathogenic	0.994
NPHS1	O60500-1.1	Y1139L	Pathogenic	0.982
NPHS1	O60500-1.1	Y1139M	Pathogenic	0.964
NPHS1	O60500-1.1	Y1139N	Pathogenic	0.996
NPHS1	O60500-1.1	Y1139P	Pathogenic	0.963
NPHS1	O60500-1.1	Y1139Q	Pathogenic	0.992
NPHS1	O60500-1.1	Y1139R	Pathogenic	0.994
NPHS1	O60500-1.1	Y1139S	Pathogenic	0.994
NPHS1	O60500-1.1	Y1139T	Pathogenic	0.986
NPHS1	O60500-1.1	Y1139V	Pathogenic	0.976
NPHS1	O60500-1.1	Y1139W	Pathogenic	0.998
NPHS1	O60500-1.1	R1140A	Neutral	0.043
NPHS1	O60500-1.1	R1140C	Neutral	0.034
NPHS1	O60500-1.1	R1140D	Neutral	0.003
NPHS1	O60500-1.1	R1140E	Neutral	0.006
NPHS1	O60500-1.1	R1140F	Neutral	0.035
NPHS1	O60500-1.1	R1140G	Neutral	0.029
NPHS1	O60500-1.1	R1140H	Neutral	0.015
NPHS1	O60500-1.1	R1140I	Neutral	0.046
NPHS1	O60500-1.1	R1140K	Neutral	0.004
NPHS1	O60500-1.1	R1140L	Neutral	0.058
NPHS1	O60500-1.1	R1140M	Neutral	0.044
NPHS1	O60500-1.1	R1140N	Neutral	0.009
NPHS1	O60500-1.1	R1140P	Neutral	0.031
NPHS1	O60500-1.1	R1140Q	Neutral	0.015
NPHS1	O60500-1.1	R1140S	Neutral	0.023
NPHS1	O60500-1.1	R1140T	Neutral	0.022
NPHS1	O60500-1.1	R1140V	Neutral	0.031
NPHS1	O60500-1.1	R1140W	Neutral	0.07
NPHS1	O60500-1.1	R1140Y	Neutral	0.014
NPHS1	O60500-1.1	S1141A	Neutral	0.398
NPHS1	O60500-1.1	S1141C	Neutral	0.489
NPHS1	O60500-1.1	S1141D	Pathogenic	0.512
NPHS1	O60500-1.1	S1141E	Pathogenic	0.569
NPHS1	O60500-1.1	S1141F	Pathogenic	0.871
NPHS1	O60500-1.1	S1141G	Neutral	0.305
NPHS1	O60500-1.1	S1141H	Neutral	0.365
NPHS1	O60500-1.1	S1141I	Pathogenic	0.842
NPHS1	O60500-1.1	S1141K	Pathogenic	0.804
NPHS1	O60500-1.1	S1141L	Pathogenic	0.821
NPHS1	O60500-1.1	S1141M	Pathogenic	0.773
NPHS1	O60500-1.1	S1141N	Pathogenic	0.578
NPHS1	O60500-1.1	S1141P	Neutral	0.415
NPHS1	O60500-1.1	S1141Q	Neutral	0.443
NPHS1	O60500-1.1	S1141R	Pathogenic	0.793
NPHS1	O60500-1.1	S1141T	Neutral	0.46
NPHS1	O60500-1.1	S1141V	Pathogenic	0.587
NPHS1	O60500-1.1	S1141W	Pathogenic	0.946
NPHS1	O60500-1.1	S1141Y	Pathogenic	0.695
NPHS1	O60500-1.1	L1142A	Neutral	0.012
NPHS1	O60500-1.1	L1142C	Neutral	0.003
NPHS1	O60500-1.1	L1142D	Neutral	0.01
NPHS1	O60500-1.1	L1142E	Neutral	0.008
NPHS1	O60500-1.1	L1142F	Neutral	0.001
NPHS1	O60500-1.1	L1142G	Neutral	0.009
NPHS1	O60500-1.1	L1142H	Neutral	0.002
NPHS1	O60500-1.1	L1142I	Neutral	0.002
NPHS1	O60500-1.1	L1142K	Neutral	0.019
NPHS1	O60500-1.1	L1142M	Neutral	0.003
NPHS1	O60500-1.1	L1142N	Neutral	0.011
NPHS1	O60500-1.1	L1142P	Neutral	0.002
NPHS1	O60500-1.1	L1142Q	Neutral	0.006
NPHS1	O60500-1.1	L1142R	Neutral	0.026
NPHS1	O60500-1.1	L1142S	Neutral	0.012
NPHS1	O60500-1.1	L1142T	Neutral	0.007
NPHS1	O60500-1.1	L1142V	Neutral	0.003
NPHS1	O60500-1.1	L1142W	Neutral	0.002
NPHS1	O60500-1.1	L1142Y	Neutral	0.002
NPHS1	O60500-1.1	R1143A	Neutral	0.486
NPHS1	O60500-1.1	R1143C	Neutral	0.425
NPHS1	O60500-1.1	R1143D	Neutral	0.067
NPHS1	O60500-1.1	R1143E	Neutral	0.113
NPHS1	O60500-1.1	R1143F	Neutral	0.436
NPHS1	O60500-1.1	R1143G	Neutral	0.386
NPHS1	O60500-1.1	R1143H	Neutral	0.245
NPHS1	O60500-1.1	R1143I	Pathogenic	0.506
NPHS1	O60500-1.1	R1143K	Neutral	0.084
NPHS1	O60500-1.1	R1143L	Pathogenic	0.567
NPHS1	O60500-1.1	R1143M	Neutral	0.493
NPHS1	O60500-1.1	R1143N	Neutral	0.155
NPHS1	O60500-1.1	R1143P	Neutral	0.404
NPHS1	O60500-1.1	R1143Q	Neutral	0.24
NPHS1	O60500-1.1	R1143S	Neutral	0.33
NPHS1	O60500-1.1	R1143T	Neutral	0.322
NPHS1	O60500-1.1	R1143V	Neutral	0.401
NPHS1	O60500-1.1	R1143W	Pathogenic	0.617
NPHS1	O60500-1.1	R1143Y	Neutral	0.226
NPHS1	O60500-1.1	D1144A	Pathogenic	0.575
NPHS1	O60500-1.1	D1144C	Pathogenic	0.612
NPHS1	O60500-1.1	D1144E	Pathogenic	0.587
NPHS1	O60500-1.1	D1144F	Pathogenic	0.929
NPHS1	O60500-1.1	D1144G	Pathogenic	0.666
NPHS1	O60500-1.1	D1144H	Pathogenic	0.625
NPHS1	O60500-1.1	D1144I	Pathogenic	0.912
NPHS1	O60500-1.1	D1144K	Neutral	0.474
NPHS1	O60500-1.1	D1144L	Pathogenic	0.857
NPHS1	O60500-1.1	D1144M	Pathogenic	0.816
NPHS1	O60500-1.1	D1144N	Neutral	0.425
NPHS1	O60500-1.1	D1144P	Pathogenic	0.683
NPHS1	O60500-1.1	D1144Q	Pathogenic	0.572
NPHS1	O60500-1.1	D1144R	Neutral	0.457
NPHS1	O60500-1.1	D1144S	Pathogenic	0.61
NPHS1	O60500-1.1	D1144T	Pathogenic	0.526
NPHS1	O60500-1.1	D1144V	Pathogenic	0.735
NPHS1	O60500-1.1	D1144W	Pathogenic	0.971
NPHS1	O60500-1.1	D1144Y	Pathogenic	0.816
NPHS1	O60500-1.1	F1145A	Pathogenic	0.976
NPHS1	O60500-1.1	F1145C	Pathogenic	0.904
NPHS1	O60500-1.1	F1145D	Pathogenic	0.987
NPHS1	O60500-1.1	F1145E	Pathogenic	0.976
NPHS1	O60500-1.1	F1145G	Pathogenic	0.985
NPHS1	O60500-1.1	F1145H	Pathogenic	0.959
NPHS1	O60500-1.1	F1145I	Pathogenic	0.724
NPHS1	O60500-1.1	F1145K	Pathogenic	0.974
NPHS1	O60500-1.1	F1145L	Pathogenic	0.745
NPHS1	O60500-1.1	F1145M	Pathogenic	0.854
NPHS1	O60500-1.1	F1145N	Pathogenic	0.981
NPHS1	O60500-1.1	F1145P	Pathogenic	0.851
NPHS1	O60500-1.1	F1145Q	Pathogenic	0.951
NPHS1	O60500-1.1	F1145R	Pathogenic	0.981
NPHS1	O60500-1.1	F1145S	Pathogenic	0.983
NPHS1	O60500-1.1	F1145T	Pathogenic	0.959
NPHS1	O60500-1.1	F1145V	Pathogenic	0.863
NPHS1	O60500-1.1	F1145W	Pathogenic	0.919
NPHS1	O60500-1.1	F1145Y	Pathogenic	0.963
NPHS1	O60500-1.1	S1146A	Neutral	0.097
NPHS1	O60500-1.1	S1146C	Neutral	0.134
NPHS1	O60500-1.1	S1146D	Neutral	0.145
NPHS1	O60500-1.1	S1146E	Neutral	0.176
NPHS1	O60500-1.1	S1146F	Pathogenic	0.523
NPHS1	O60500-1.1	S1146G	Neutral	0.066
NPHS1	O60500-1.1	S1146H	Neutral	0.085
NPHS1	O60500-1.1	S1146I	Neutral	0.464
NPHS1	O60500-1.1	S1146K	Neutral	0.4
NPHS1	O60500-1.1	S1146L	Neutral	0.426
NPHS1	O60500-1.1	S1146M	Neutral	0.355
NPHS1	O60500-1.1	S1146N	Neutral	0.181
NPHS1	O60500-1.1	S1146P	Neutral	0.103
NPHS1	O60500-1.1	S1146Q	Neutral	0.114
NPHS1	O60500-1.1	S1146R	Neutral	0.383
NPHS1	O60500-1.1	S1146T	Neutral	0.121
NPHS1	O60500-1.1	S1146V	Neutral	0.187
NPHS1	O60500-1.1	S1146W	Pathogenic	0.739
NPHS1	O60500-1.1	S1146Y	Neutral	0.269
NPHS1	O60500-1.1	P1147A	Pathogenic	0.891
NPHS1	O60500-1.1	P1147C	Pathogenic	0.654
NPHS1	O60500-1.1	P1147D	Pathogenic	0.96
NPHS1	O60500-1.1	P1147E	Pathogenic	0.968
NPHS1	O60500-1.1	P1147F	Pathogenic	0.917
NPHS1	O60500-1.1	P1147G	Pathogenic	0.932
NPHS1	O60500-1.1	P1147H	Pathogenic	0.889
NPHS1	O60500-1.1	P1147I	Pathogenic	0.929
NPHS1	O60500-1.1	P1147K	Pathogenic	0.99
NPHS1	O60500-1.1	P1147L	Pathogenic	0.918
NPHS1	O60500-1.1	P1147M	Pathogenic	0.892
NPHS1	O60500-1.1	P1147N	Pathogenic	0.934
NPHS1	O60500-1.1	P1147Q	Pathogenic	0.948
NPHS1	O60500-1.1	P1147R	Pathogenic	0.989
NPHS1	O60500-1.1	P1147S	Pathogenic	0.922
NPHS1	O60500-1.1	P1147T	Pathogenic	0.846
NPHS1	O60500-1.1	P1147V	Pathogenic	0.838
NPHS1	O60500-1.1	P1147W	Pathogenic	0.977
NPHS1	O60500-1.1	P1147Y	Pathogenic	0.847
NPHS1	O60500-1.1	Q1148A	Neutral	0.25
NPHS1	O60500-1.1	Q1148C	Neutral	0.207
NPHS1	O60500-1.1	Q1148D	Neutral	0.225
NPHS1	O60500-1.1	Q1148E	Neutral	0.258
NPHS1	O60500-1.1	Q1148F	Neutral	0.423
NPHS1	O60500-1.1	Q1148G	Neutral	0.181
NPHS1	O60500-1.1	Q1148H	Neutral	0.121
NPHS1	O60500-1.1	Q1148I	Neutral	0.366
NPHS1	O60500-1.1	Q1148K	Neutral	0.365
NPHS1	O60500-1.1	Q1148L	Neutral	0.425
NPHS1	O60500-1.1	Q1148M	Neutral	0.45
NPHS1	O60500-1.1	Q1148N	Neutral	0.167
NPHS1	O60500-1.1	Q1148P	Neutral	0.263
NPHS1	O60500-1.1	Q1148R	Neutral	0.444
NPHS1	O60500-1.1	Q1148S	Neutral	0.205
NPHS1	O60500-1.1	Q1148T	Neutral	0.143
NPHS1	O60500-1.1	Q1148V	Neutral	0.26
NPHS1	O60500-1.1	Q1148W	Pathogenic	0.808
NPHS1	O60500-1.1	Q1148Y	Neutral	0.354
NPHS1	O60500-1.1	L1149A	Pathogenic	0.885
NPHS1	O60500-1.1	L1149C	Pathogenic	0.644
NPHS1	O60500-1.1	L1149D	Pathogenic	0.868
NPHS1	O60500-1.1	L1149E	Pathogenic	0.84
NPHS1	O60500-1.1	L1149F	Neutral	0.358
NPHS1	O60500-1.1	L1149G	Pathogenic	0.852
NPHS1	O60500-1.1	L1149H	Pathogenic	0.575
NPHS1	O60500-1.1	L1149I	Neutral	0.494
NPHS1	O60500-1.1	L1149K	Pathogenic	0.923
NPHS1	O60500-1.1	L1149M	Pathogenic	0.627
NPHS1	O60500-1.1	L1149N	Pathogenic	0.871
NPHS1	O60500-1.1	L1149P	Pathogenic	0.522
NPHS1	O60500-1.1	L1149Q	Pathogenic	0.789
NPHS1	O60500-1.1	L1149R	Pathogenic	0.944
NPHS1	O60500-1.1	L1149S	Pathogenic	0.882
NPHS1	O60500-1.1	L1149T	Pathogenic	0.818
NPHS1	O60500-1.1	L1149V	Pathogenic	0.644
NPHS1	O60500-1.1	L1149W	Neutral	0.491
NPHS1	O60500-1.1	L1149Y	Pathogenic	0.532
NPHS1	O60500-1.1	P1150A	Neutral	0.098
NPHS1	O60500-1.1	P1150C	Neutral	0.025
NPHS1	O60500-1.1	P1150D	Neutral	0.244
NPHS1	O60500-1.1	P1150E	Neutral	0.288
NPHS1	O60500-1.1	P1150F	Neutral	0.128
NPHS1	O60500-1.1	P1150G	Neutral	0.153
NPHS1	O60500-1.1	P1150H	Neutral	0.096
NPHS1	O60500-1.1	P1150I	Neutral	0.148
NPHS1	O60500-1.1	P1150K	Pathogenic	0.558
NPHS1	O60500-1.1	P1150L	Neutral	0.129
NPHS1	O60500-1.1	P1150M	Neutral	0.099
NPHS1	O60500-1.1	P1150N	Neutral	0.159
NPHS1	O60500-1.1	P1150Q	Neutral	0.196
NPHS1	O60500-1.1	P1150R	Pathogenic	0.541
NPHS1	O60500-1.1	P1150S	Neutral	0.136
NPHS1	O60500-1.1	P1150T	Neutral	0.068
NPHS1	O60500-1.1	P1150V	Neutral	0.064
NPHS1	O60500-1.1	P1150W	Neutral	0.362
NPHS1	O60500-1.1	P1150Y	Neutral	0.069
NPHS1	O60500-1.1	P1151A	Neutral	0.452
NPHS1	O60500-1.1	P1151C	Neutral	0.16
NPHS1	O60500-1.1	P1151D	Pathogenic	0.709
NPHS1	O60500-1.1	P1151E	Pathogenic	0.754
NPHS1	O60500-1.1	P1151F	Pathogenic	0.527
NPHS1	O60500-1.1	P1151G	Pathogenic	0.578
NPHS1	O60500-1.1	P1151H	Neutral	0.447
NPHS1	O60500-1.1	P1151I	Pathogenic	0.567
NPHS1	O60500-1.1	P1151K	Pathogenic	0.905
NPHS1	O60500-1.1	P1151L	Pathogenic	0.53
NPHS1	O60500-1.1	P1151M	Neutral	0.455
NPHS1	O60500-1.1	P1151N	Pathogenic	0.589
NPHS1	O60500-1.1	P1151Q	Pathogenic	0.649
NPHS1	O60500-1.1	P1151R	Pathogenic	0.899
NPHS1	O60500-1.1	P1151S	Pathogenic	0.544
NPHS1	O60500-1.1	P1151T	Neutral	0.357
NPHS1	O60500-1.1	P1151V	Neutral	0.343
NPHS1	O60500-1.1	P1151W	Pathogenic	0.811
NPHS1	O60500-1.1	P1151Y	Neutral	0.359
NPHS1	O60500-1.1	T1152A	Neutral	0.143
NPHS1	O60500-1.1	T1152C	Neutral	0.163
NPHS1	O60500-1.1	T1152D	Neutral	0.213
NPHS1	O60500-1.1	T1152E	Neutral	0.236
NPHS1	O60500-1.1	T1152F	Neutral	0.498
NPHS1	O60500-1.1	T1152G	Neutral	0.137
NPHS1	O60500-1.1	T1152H	Neutral	0.075
NPHS1	O60500-1.1	T1152I	Pathogenic	0.538
NPHS1	O60500-1.1	T1152K	Neutral	0.491
NPHS1	O60500-1.1	T1152L	Pathogenic	0.5
NPHS1	O60500-1.1	T1152M	Neutral	0.332
NPHS1	O60500-1.1	T1152N	Neutral	0.243
NPHS1	O60500-1.1	T1152P	Neutral	0.107
NPHS1	O60500-1.1	T1152Q	Neutral	0.158
NPHS1	O60500-1.1	T1152R	Pathogenic	0.573
NPHS1	O60500-1.1	T1152S	Neutral	0.236
NPHS1	O60500-1.1	T1152V	Neutral	0.317
NPHS1	O60500-1.1	T1152W	Pathogenic	0.793
NPHS1	O60500-1.1	T1152Y	Neutral	0.25
NPHS1	O60500-1.1	Q1153A	Neutral	0.012
NPHS1	O60500-1.1	Q1153C	Neutral	0.01
NPHS1	O60500-1.1	Q1153D	Neutral	0.011
NPHS1	O60500-1.1	Q1153E	Neutral	0.013
NPHS1	O60500-1.1	Q1153F	Neutral	0.026
NPHS1	O60500-1.1	Q1153G	Neutral	0.008
NPHS1	O60500-1.1	Q1153H	Neutral	0.005
NPHS1	O60500-1.1	Q1153I	Neutral	0.021
NPHS1	O60500-1.1	Q1153K	Neutral	0.021
NPHS1	O60500-1.1	Q1153L	Neutral	0.027
NPHS1	O60500-1.1	Q1153M	Neutral	0.029
NPHS1	O60500-1.1	Q1153N	Neutral	0.007
NPHS1	O60500-1.1	Q1153P	Neutral	0.013
NPHS1	O60500-1.1	Q1153R	Neutral	0.029
NPHS1	O60500-1.1	Q1153S	Neutral	0.009
NPHS1	O60500-1.1	Q1153T	Neutral	0.006
NPHS1	O60500-1.1	Q1153V	Neutral	0.013
NPHS1	O60500-1.1	Q1153W	Neutral	0.135
NPHS1	O60500-1.1	Q1153Y	Neutral	0.02
NPHS1	O60500-1.1	E1154A	Pathogenic	0.928
NPHS1	O60500-1.1	E1154C	Pathogenic	0.872
NPHS1	O60500-1.1	E1154D	Pathogenic	0.879
NPHS1	O60500-1.1	E1154F	Pathogenic	0.973
NPHS1	O60500-1.1	E1154G	Pathogenic	0.896
NPHS1	O60500-1.1	E1154H	Pathogenic	0.872
NPHS1	O60500-1.1	E1154I	Pathogenic	0.966
NPHS1	O60500-1.1	E1154K	Pathogenic	0.891
NPHS1	O60500-1.1	E1154L	Pathogenic	0.961
NPHS1	O60500-1.1	E1154M	Pathogenic	0.948
NPHS1	O60500-1.1	E1154N	Pathogenic	0.715
NPHS1	O60500-1.1	E1154P	Pathogenic	0.933
NPHS1	O60500-1.1	E1154Q	Pathogenic	0.891
NPHS1	O60500-1.1	E1154R	Pathogenic	0.884
NPHS1	O60500-1.1	E1154S	Pathogenic	0.909
NPHS1	O60500-1.1	E1154T	Pathogenic	0.866
NPHS1	O60500-1.1	E1154V	Pathogenic	0.932
NPHS1	O60500-1.1	E1154W	Pathogenic	0.993
NPHS1	O60500-1.1	E1154Y	Pathogenic	0.948
NPHS1	O60500-1.1	E1155A	Neutral	0.403
NPHS1	O60500-1.1	E1155C	Neutral	0.262
NPHS1	O60500-1.1	E1155D	Neutral	0.274
NPHS1	O60500-1.1	E1155F	Pathogenic	0.653
NPHS1	O60500-1.1	E1155G	Neutral	0.309
NPHS1	O60500-1.1	E1155H	Neutral	0.262
NPHS1	O60500-1.1	E1155I	Pathogenic	0.597
NPHS1	O60500-1.1	E1155K	Neutral	0.298
NPHS1	O60500-1.1	E1155L	Pathogenic	0.56
NPHS1	O60500-1.1	E1155M	Neutral	0.486
NPHS1	O60500-1.1	E1155N	Neutral	0.116
NPHS1	O60500-1.1	E1155P	Neutral	0.419
NPHS1	O60500-1.1	E1155Q	Neutral	0.299
NPHS1	O60500-1.1	E1155R	Neutral	0.284
NPHS1	O60500-1.1	E1155S	Neutral	0.343
NPHS1	O60500-1.1	E1155T	Neutral	0.253
NPHS1	O60500-1.1	E1155V	Neutral	0.416
NPHS1	O60500-1.1	E1155W	Pathogenic	0.879
NPHS1	O60500-1.1	E1155Y	Neutral	0.485
NPHS1	O60500-1.1	V1156A	Neutral	0.147
NPHS1	O60500-1.1	V1156C	Neutral	0.026
NPHS1	O60500-1.1	V1156D	Neutral	0.127
NPHS1	O60500-1.1	V1156E	Neutral	0.124
NPHS1	O60500-1.1	V1156F	Neutral	0.055
NPHS1	O60500-1.1	V1156G	Neutral	0.114
NPHS1	O60500-1.1	V1156H	Neutral	0.036
NPHS1	O60500-1.1	V1156I	Neutral	0.184
NPHS1	O60500-1.1	V1156K	Neutral	0.306
NPHS1	O60500-1.1	V1156L	Neutral	0.08
NPHS1	O60500-1.1	V1156M	Neutral	0.041
NPHS1	O60500-1.1	V1156N	Neutral	0.092
NPHS1	O60500-1.1	V1156P	Neutral	0.024
NPHS1	O60500-1.1	V1156Q	Neutral	0.079
NPHS1	O60500-1.1	V1156R	Neutral	0.291
NPHS1	O60500-1.1	V1156S	Neutral	0.101
NPHS1	O60500-1.1	V1156T	Neutral	0.091
NPHS1	O60500-1.1	V1156W	Neutral	0.091
NPHS1	O60500-1.1	V1156Y	Neutral	0.04
NPHS1	O60500-1.1	S1157A	Neutral	0.067
NPHS1	O60500-1.1	S1157C	Neutral	0.094
NPHS1	O60500-1.1	S1157D	Neutral	0.102
NPHS1	O60500-1.1	S1157E	Neutral	0.125
NPHS1	O60500-1.1	S1157F	Neutral	0.424
NPHS1	O60500-1.1	S1157G	Neutral	0.045
NPHS1	O60500-1.1	S1157H	Neutral	0.059
NPHS1	O60500-1.1	S1157I	Neutral	0.367
NPHS1	O60500-1.1	S1157K	Neutral	0.309
NPHS1	O60500-1.1	S1157L	Neutral	0.332
NPHS1	O60500-1.1	S1157M	Neutral	0.269
NPHS1	O60500-1.1	S1157N	Neutral	0.129
NPHS1	O60500-1.1	S1157P	Neutral	0.071
NPHS1	O60500-1.1	S1157Q	Neutral	0.08
NPHS1	O60500-1.1	S1157R	Neutral	0.294
NPHS1	O60500-1.1	S1157T	Neutral	0.085
NPHS1	O60500-1.1	S1157V	Neutral	0.134
NPHS1	O60500-1.1	S1157W	Pathogenic	0.655
NPHS1	O60500-1.1	S1157Y	Neutral	0.198
NPHS1	O60500-1.1	Y1158A	Pathogenic	0.811
NPHS1	O60500-1.1	Y1158C	Pathogenic	0.517
NPHS1	O60500-1.1	Y1158D	Pathogenic	0.89
NPHS1	O60500-1.1	Y1158E	Pathogenic	0.867
NPHS1	O60500-1.1	Y1158F	Pathogenic	0.892
NPHS1	O60500-1.1	Y1158G	Pathogenic	0.877
NPHS1	O60500-1.1	Y1158H	Pathogenic	0.892
NPHS1	O60500-1.1	Y1158I	Pathogenic	0.688
NPHS1	O60500-1.1	Y1158K	Pathogenic	0.856
NPHS1	O60500-1.1	Y1158L	Pathogenic	0.655
NPHS1	O60500-1.1	Y1158M	Neutral	0.485
NPHS1	O60500-1.1	Y1158N	Pathogenic	0.893
NPHS1	O60500-1.1	Y1158P	Neutral	0.475
NPHS1	O60500-1.1	Y1158Q	Pathogenic	0.822
NPHS1	O60500-1.1	Y1158R	Pathogenic	0.861
NPHS1	O60500-1.1	Y1158S	Pathogenic	0.861
NPHS1	O60500-1.1	Y1158T	Pathogenic	0.715
NPHS1	O60500-1.1	Y1158V	Pathogenic	0.591
NPHS1	O60500-1.1	Y1158W	Pathogenic	0.941
NPHS1	O60500-1.1	S1159A	Neutral	0.001
NPHS1	O60500-1.1	S1159C	Neutral	0.001
NPHS1	O60500-1.1	S1159D	Neutral	0.001
NPHS1	O60500-1.1	S1159E	Neutral	0.002
NPHS1	O60500-1.1	S1159F	Neutral	0.009
NPHS1	O60500-1.1	S1159G	Neutral	0.001
NPHS1	O60500-1.1	S1159H	Neutral	0.001
NPHS1	O60500-1.1	S1159I	Neutral	0.007
NPHS1	O60500-1.1	S1159K	Neutral	0.006
NPHS1	O60500-1.1	S1159L	Neutral	0.006
NPHS1	O60500-1.1	S1159M	Neutral	0.005
NPHS1	O60500-1.1	S1159N	Neutral	0.002
NPHS1	O60500-1.1	S1159P	Neutral	0.001
NPHS1	O60500-1.1	S1159Q	Neutral	0.001
NPHS1	O60500-1.1	S1159R	Neutral	0.005
NPHS1	O60500-1.1	S1159T	Neutral	0.001
NPHS1	O60500-1.1	S1159V	Neutral	0.002
NPHS1	O60500-1.1	S1159W	Neutral	0.023
NPHS1	O60500-1.1	S1159Y	Neutral	0.003
NPHS1	O60500-1.1	R1160A	Neutral	0.005
NPHS1	O60500-1.1	R1160C	Neutral	0.004
NPHS1	O60500-1.1	R1160D	Neutral	0.0
NPHS1	O60500-1.1	R1160E	Neutral	0.001
NPHS1	O60500-1.1	R1160F	Neutral	0.004
NPHS1	O60500-1.1	R1160G	Neutral	0.003
NPHS1	O60500-1.1	R1160H	Neutral	0.002
NPHS1	O60500-1.1	R1160I	Neutral	0.006
NPHS1	O60500-1.1	R1160K	Neutral	0.001
NPHS1	O60500-1.1	R1160L	Neutral	0.007
NPHS1	O60500-1.1	R1160M	Neutral	0.005
NPHS1	O60500-1.1	R1160N	Neutral	0.001
NPHS1	O60500-1.1	R1160P	Neutral	0.004
NPHS1	O60500-1.1	R1160Q	Neutral	0.002
NPHS1	O60500-1.1	R1160S	Neutral	0.003
NPHS1	O60500-1.1	R1160T	Neutral	0.003
NPHS1	O60500-1.1	R1160V	Neutral	0.004
NPHS1	O60500-1.1	R1160W	Neutral	0.009
NPHS1	O60500-1.1	R1160Y	Neutral	0.002
NPHS1	O60500-1.1	G1161A	Neutral	0.006
NPHS1	O60500-1.1	G1161C	Neutral	0.008
NPHS1	O60500-1.1	G1161D	Neutral	0.014
NPHS1	O60500-1.1	G1161E	Neutral	0.012
NPHS1	O60500-1.1	G1161F	Neutral	0.078
NPHS1	O60500-1.1	G1161H	Neutral	0.007
NPHS1	O60500-1.1	G1161I	Neutral	0.043
NPHS1	O60500-1.1	G1161K	Neutral	0.037
NPHS1	O60500-1.1	G1161L	Neutral	0.037
NPHS1	O60500-1.1	G1161M	Neutral	0.028
NPHS1	O60500-1.1	G1161N	Neutral	0.019
NPHS1	O60500-1.1	G1161P	Neutral	0.009
NPHS1	O60500-1.1	G1161Q	Neutral	0.007
NPHS1	O60500-1.1	G1161R	Neutral	0.051
NPHS1	O60500-1.1	G1161S	Neutral	0.005
NPHS1	O60500-1.1	G1161T	Neutral	0.005
NPHS1	O60500-1.1	G1161V	Neutral	0.017
NPHS1	O60500-1.1	G1161W	Neutral	0.327
NPHS1	O60500-1.1	G1161Y	Neutral	0.028
NPHS1	O60500-1.1	F1162A	Neutral	0.031
NPHS1	O60500-1.1	F1162C	Neutral	0.007
NPHS1	O60500-1.1	F1162D	Neutral	0.058
NPHS1	O60500-1.1	F1162E	Neutral	0.032
NPHS1	O60500-1.1	F1162G	Neutral	0.051
NPHS1	O60500-1.1	F1162H	Neutral	0.018
NPHS1	O60500-1.1	F1162I	Neutral	0.002
NPHS1	O60500-1.1	F1162K	Neutral	0.029
NPHS1	O60500-1.1	F1162L	Neutral	0.002
NPHS1	O60500-1.1	F1162M	Neutral	0.005
NPHS1	O60500-1.1	F1162N	Neutral	0.041
NPHS1	O60500-1.1	F1162P	Neutral	0.005
NPHS1	O60500-1.1	F1162Q	Neutral	0.015
NPHS1	O60500-1.1	F1162R	Neutral	0.04
NPHS1	O60500-1.1	F1162S	Neutral	0.045
NPHS1	O60500-1.1	F1162T	Neutral	0.019
NPHS1	O60500-1.1	F1162V	Neutral	0.005
NPHS1	O60500-1.1	F1162W	Neutral	0.009
NPHS1	O60500-1.1	F1162Y	Neutral	0.02
NPHS1	O60500-1.1	T1163A	Neutral	0.0
NPHS1	O60500-1.1	T1163C	Neutral	0.0
NPHS1	O60500-1.1	T1163D	Neutral	0.0
NPHS1	O60500-1.1	T1163E	Neutral	0.0
NPHS1	O60500-1.1	T1163F	Neutral	0.001
NPHS1	O60500-1.1	T1163G	Neutral	0.0
NPHS1	O60500-1.1	T1163H	Neutral	0.0
NPHS1	O60500-1.1	T1163I	Neutral	0.001
NPHS1	O60500-1.1	T1163K	Neutral	0.001
NPHS1	O60500-1.1	T1163L	Neutral	0.001
NPHS1	O60500-1.1	T1163M	Neutral	0.0
NPHS1	O60500-1.1	T1163N	Neutral	0.0
NPHS1	O60500-1.1	T1163P	Neutral	0.0
NPHS1	O60500-1.1	T1163Q	Neutral	0.0
NPHS1	O60500-1.1	T1163R	Neutral	0.001
NPHS1	O60500-1.1	T1163S	Neutral	0.0
NPHS1	O60500-1.1	T1163V	Neutral	0.0
NPHS1	O60500-1.1	T1163W	Neutral	0.004
NPHS1	O60500-1.1	T1163Y	Neutral	0.0
NPHS1	O60500-1.1	G1164A	Neutral	0.005
NPHS1	O60500-1.1	G1164C	Neutral	0.007
NPHS1	O60500-1.1	G1164D	Neutral	0.012
NPHS1	O60500-1.1	G1164E	Neutral	0.01
NPHS1	O60500-1.1	G1164F	Neutral	0.065
NPHS1	O60500-1.1	G1164H	Neutral	0.006
NPHS1	O60500-1.1	G1164I	Neutral	0.036
NPHS1	O60500-1.1	G1164K	Neutral	0.031
NPHS1	O60500-1.1	G1164L	Neutral	0.031
NPHS1	O60500-1.1	G1164M	Neutral	0.023
NPHS1	O60500-1.1	G1164N	Neutral	0.015
NPHS1	O60500-1.1	G1164P	Neutral	0.007
NPHS1	O60500-1.1	G1164Q	Neutral	0.006
NPHS1	O60500-1.1	G1164R	Neutral	0.042
NPHS1	O60500-1.1	G1164S	Neutral	0.004
NPHS1	O60500-1.1	G1164T	Neutral	0.004
NPHS1	O60500-1.1	G1164V	Neutral	0.014
NPHS1	O60500-1.1	G1164W	Neutral	0.286
NPHS1	O60500-1.1	G1164Y	Neutral	0.023
NPHS1	O60500-1.1	E1165A	Neutral	0.004
NPHS1	O60500-1.1	E1165C	Neutral	0.002
NPHS1	O60500-1.1	E1165D	Neutral	0.002
NPHS1	O60500-1.1	E1165F	Neutral	0.011
NPHS1	O60500-1.1	E1165G	Neutral	0.003
NPHS1	O60500-1.1	E1165H	Neutral	0.002
NPHS1	O60500-1.1	E1165I	Neutral	0.009
NPHS1	O60500-1.1	E1165K	Neutral	0.003
NPHS1	O60500-1.1	E1165L	Neutral	0.008
NPHS1	O60500-1.1	E1165M	Neutral	0.006
NPHS1	O60500-1.1	E1165N	Neutral	0.001
NPHS1	O60500-1.1	E1165P	Neutral	0.004
NPHS1	O60500-1.1	E1165Q	Neutral	0.003
NPHS1	O60500-1.1	E1165R	Neutral	0.002
NPHS1	O60500-1.1	E1165S	Neutral	0.003
NPHS1	O60500-1.1	E1165T	Neutral	0.002
NPHS1	O60500-1.1	E1165V	Neutral	0.004
NPHS1	O60500-1.1	E1165W	Neutral	0.043
NPHS1	O60500-1.1	E1165Y	Neutral	0.006
NPHS1	O60500-1.1	D1166A	Neutral	0.001
NPHS1	O60500-1.1	D1166C	Neutral	0.001
NPHS1	O60500-1.1	D1166E	Neutral	0.001
NPHS1	O60500-1.1	D1166F	Neutral	0.007
NPHS1	O60500-1.1	D1166G	Neutral	0.001
NPHS1	O60500-1.1	D1166H	Neutral	0.001
NPHS1	O60500-1.1	D1166I	Neutral	0.005
NPHS1	O60500-1.1	D1166K	Neutral	0.0
NPHS1	O60500-1.1	D1166L	Neutral	0.003
NPHS1	O60500-1.1	D1166M	Neutral	0.002
NPHS1	O60500-1.1	D1166N	Neutral	0.0
NPHS1	O60500-1.1	D1166P	Neutral	0.001
NPHS1	O60500-1.1	D1166Q	Neutral	0.001
NPHS1	O60500-1.1	D1166R	Neutral	0.0
NPHS1	O60500-1.1	D1166S	Neutral	0.001
NPHS1	O60500-1.1	D1166T	Neutral	0.001
NPHS1	O60500-1.1	D1166V	Neutral	0.001
NPHS1	O60500-1.1	D1166W	Neutral	0.017
NPHS1	O60500-1.1	D1166Y	Neutral	0.002
NPHS1	O60500-1.1	E1167A	Neutral	0.007
NPHS1	O60500-1.1	E1167C	Neutral	0.004
NPHS1	O60500-1.1	E1167D	Neutral	0.004
NPHS1	O60500-1.1	E1167F	Neutral	0.02
NPHS1	O60500-1.1	E1167G	Neutral	0.005
NPHS1	O60500-1.1	E1167H	Neutral	0.004
NPHS1	O60500-1.1	E1167I	Neutral	0.016
NPHS1	O60500-1.1	E1167K	Neutral	0.005
NPHS1	O60500-1.1	E1167L	Neutral	0.014
NPHS1	O60500-1.1	E1167M	Neutral	0.01
NPHS1	O60500-1.1	E1167N	Neutral	0.001
NPHS1	O60500-1.1	E1167P	Neutral	0.008
NPHS1	O60500-1.1	E1167Q	Neutral	0.005
NPHS1	O60500-1.1	E1167R	Neutral	0.004
NPHS1	O60500-1.1	E1167S	Neutral	0.006
NPHS1	O60500-1.1	E1167T	Neutral	0.004
NPHS1	O60500-1.1	E1167V	Neutral	0.008
NPHS1	O60500-1.1	E1167W	Neutral	0.073
NPHS1	O60500-1.1	E1167Y	Neutral	0.01
NPHS1	O60500-1.1	D1168A	Neutral	0.001
NPHS1	O60500-1.1	D1168C	Neutral	0.002
NPHS1	O60500-1.1	D1168E	Neutral	0.001
NPHS1	O60500-1.1	D1168F	Neutral	0.014
NPHS1	O60500-1.1	D1168G	Neutral	0.002
NPHS1	O60500-1.1	D1168H	Neutral	0.002
NPHS1	O60500-1.1	D1168I	Neutral	0.011
NPHS1	O60500-1.1	D1168K	Neutral	0.001
NPHS1	O60500-1.1	D1168L	Neutral	0.006
NPHS1	O60500-1.1	D1168M	Neutral	0.005
NPHS1	O60500-1.1	D1168N	Neutral	0.001
NPHS1	O60500-1.1	D1168P	Neutral	0.002
NPHS1	O60500-1.1	D1168Q	Neutral	0.001
NPHS1	O60500-1.1	D1168R	Neutral	0.001
NPHS1	O60500-1.1	D1168S	Neutral	0.002
NPHS1	O60500-1.1	D1168T	Neutral	0.001
NPHS1	O60500-1.1	D1168V	Neutral	0.003
NPHS1	O60500-1.1	D1168W	Neutral	0.035
NPHS1	O60500-1.1	D1168Y	Neutral	0.005
NPHS1	O60500-1.1	M1169A	Neutral	0.108
NPHS1	O60500-1.1	M1169C	Neutral	0.028
NPHS1	O60500-1.1	M1169D	Neutral	0.133
NPHS1	O60500-1.1	M1169E	Neutral	0.11
NPHS1	O60500-1.1	M1169F	Neutral	0.034
NPHS1	O60500-1.1	M1169G	Neutral	0.119
NPHS1	O60500-1.1	M1169H	Neutral	0.031
NPHS1	O60500-1.1	M1169I	Neutral	0.04
NPHS1	O60500-1.1	M1169K	Neutral	0.22
NPHS1	O60500-1.1	M1169L	Neutral	0.051
NPHS1	O60500-1.1	M1169N	Neutral	0.137
NPHS1	O60500-1.1	M1169P	Neutral	0.025
NPHS1	O60500-1.1	M1169Q	Neutral	0.116
NPHS1	O60500-1.1	M1169R	Neutral	0.282
NPHS1	O60500-1.1	M1169S	Neutral	0.15
NPHS1	O60500-1.1	M1169T	Neutral	0.066
NPHS1	O60500-1.1	M1169V	Neutral	0.028
NPHS1	O60500-1.1	M1169W	Neutral	0.084
NPHS1	O60500-1.1	M1169Y	Neutral	0.018
NPHS1	O60500-1.1	A1170C	Neutral	0.002
NPHS1	O60500-1.1	A1170D	Neutral	0.002
NPHS1	O60500-1.1	A1170E	Neutral	0.003
NPHS1	O60500-1.1	A1170F	Neutral	0.008
NPHS1	O60500-1.1	A1170G	Neutral	0.001
NPHS1	O60500-1.1	A1170H	Neutral	0.001
NPHS1	O60500-1.1	A1170I	Neutral	0.009
NPHS1	O60500-1.1	A1170K	Neutral	0.009
NPHS1	O60500-1.1	A1170L	Neutral	0.008
NPHS1	O60500-1.1	A1170M	Neutral	0.004
NPHS1	O60500-1.1	A1170N	Neutral	0.001
NPHS1	O60500-1.1	A1170P	Neutral	0.001
NPHS1	O60500-1.1	A1170Q	Neutral	0.002
NPHS1	O60500-1.1	A1170R	Neutral	0.012
NPHS1	O60500-1.1	A1170S	Neutral	0.001
NPHS1	O60500-1.1	A1170T	Neutral	0.001
NPHS1	O60500-1.1	A1170V	Neutral	0.004
NPHS1	O60500-1.1	A1170W	Neutral	0.02
NPHS1	O60500-1.1	A1170Y	Neutral	0.003
NPHS1	O60500-1.1	F1171A	Neutral	0.295
NPHS1	O60500-1.1	F1171C	Neutral	0.089
NPHS1	O60500-1.1	F1171D	Neutral	0.442
NPHS1	O60500-1.1	F1171E	Neutral	0.298
NPHS1	O60500-1.1	F1171G	Neutral	0.41
NPHS1	O60500-1.1	F1171H	Neutral	0.196
NPHS1	O60500-1.1	F1171I	Neutral	0.027
NPHS1	O60500-1.1	F1171K	Neutral	0.28
NPHS1	O60500-1.1	F1171L	Neutral	0.03
NPHS1	O60500-1.1	F1171M	Neutral	0.058
NPHS1	O60500-1.1	F1171N	Neutral	0.354
NPHS1	O60500-1.1	F1171P	Neutral	0.056
NPHS1	O60500-1.1	F1171Q	Neutral	0.169
NPHS1	O60500-1.1	F1171R	Neutral	0.351
NPHS1	O60500-1.1	F1171S	Neutral	0.378
NPHS1	O60500-1.1	F1171T	Neutral	0.197
NPHS1	O60500-1.1	F1171V	Neutral	0.062
NPHS1	O60500-1.1	F1171W	Neutral	0.106
NPHS1	O60500-1.1	F1171Y	Neutral	0.213
NPHS1	O60500-1.1	P1172A	Neutral	0.007
NPHS1	O60500-1.1	P1172C	Neutral	0.002
NPHS1	O60500-1.1	P1172D	Neutral	0.021
NPHS1	O60500-1.1	P1172E	Neutral	0.027
NPHS1	O60500-1.1	P1172F	Neutral	0.01
NPHS1	O60500-1.1	P1172G	Neutral	0.012
NPHS1	O60500-1.1	P1172H	Neutral	0.007
NPHS1	O60500-1.1	P1172I	Neutral	0.012
NPHS1	O60500-1.1	P1172K	Neutral	0.079
NPHS1	O60500-1.1	P1172L	Neutral	0.01
NPHS1	O60500-1.1	P1172M	Neutral	0.007
NPHS1	O60500-1.1	P1172N	Neutral	0.013
NPHS1	O60500-1.1	P1172Q	Neutral	0.016
NPHS1	O60500-1.1	P1172R	Neutral	0.074
NPHS1	O60500-1.1	P1172S	Neutral	0.011
NPHS1	O60500-1.1	P1172T	Neutral	0.005
NPHS1	O60500-1.1	P1172V	Neutral	0.005
NPHS1	O60500-1.1	P1172W	Neutral	0.037
NPHS1	O60500-1.1	P1172Y	Neutral	0.005
NPHS1	O60500-1.1	G1173A	Neutral	0.01
NPHS1	O60500-1.1	G1173C	Neutral	0.013
NPHS1	O60500-1.1	G1173D	Neutral	0.023
NPHS1	O60500-1.1	G1173E	Neutral	0.019
NPHS1	O60500-1.1	G1173F	Neutral	0.119
NPHS1	O60500-1.1	G1173H	Neutral	0.011
NPHS1	O60500-1.1	G1173I	Neutral	0.066
NPHS1	O60500-1.1	G1173K	Neutral	0.058
NPHS1	O60500-1.1	G1173L	Neutral	0.058
NPHS1	O60500-1.1	G1173M	Neutral	0.043
NPHS1	O60500-1.1	G1173N	Neutral	0.029
NPHS1	O60500-1.1	G1173P	Neutral	0.014
NPHS1	O60500-1.1	G1173Q	Neutral	0.012
NPHS1	O60500-1.1	G1173R	Neutral	0.078
NPHS1	O60500-1.1	G1173S	Neutral	0.008
NPHS1	O60500-1.1	G1173T	Neutral	0.008
NPHS1	O60500-1.1	G1173V	Neutral	0.028
NPHS1	O60500-1.1	G1173W	Neutral	0.436
NPHS1	O60500-1.1	G1173Y	Neutral	0.043
NPHS1	O60500-1.1	H1174A	Neutral	0.17
NPHS1	O60500-1.1	H1174C	Neutral	0.193
NPHS1	O60500-1.1	H1174D	Neutral	0.337
NPHS1	O60500-1.1	H1174E	Neutral	0.289
NPHS1	O60500-1.1	H1174F	Pathogenic	0.553
NPHS1	O60500-1.1	H1174G	Neutral	0.231
NPHS1	O60500-1.1	H1174I	Neutral	0.304
NPHS1	O60500-1.1	H1174K	Neutral	0.358
NPHS1	O60500-1.1	H1174L	Neutral	0.273
NPHS1	O60500-1.1	H1174M	Neutral	0.218
NPHS1	O60500-1.1	H1174N	Neutral	0.439
NPHS1	O60500-1.1	H1174P	Neutral	0.179
NPHS1	O60500-1.1	H1174Q	Neutral	0.163
NPHS1	O60500-1.1	H1174R	Pathogenic	0.536
NPHS1	O60500-1.1	H1174S	Neutral	0.207
NPHS1	O60500-1.1	H1174T	Neutral	0.093
NPHS1	O60500-1.1	H1174V	Neutral	0.177
NPHS1	O60500-1.1	H1174W	Pathogenic	0.761
NPHS1	O60500-1.1	H1174Y	Pathogenic	0.579
NPHS1	O60500-1.1	L1175A	Neutral	0.018
NPHS1	O60500-1.1	L1175C	Neutral	0.004
NPHS1	O60500-1.1	L1175D	Neutral	0.016
NPHS1	O60500-1.1	L1175E	Neutral	0.013
NPHS1	O60500-1.1	L1175F	Neutral	0.001
NPHS1	O60500-1.1	L1175G	Neutral	0.014
NPHS1	O60500-1.1	L1175H	Neutral	0.003
NPHS1	O60500-1.1	L1175I	Neutral	0.002
NPHS1	O60500-1.1	L1175K	Neutral	0.029
NPHS1	O60500-1.1	L1175M	Neutral	0.004
NPHS1	O60500-1.1	L1175N	Neutral	0.016
NPHS1	O60500-1.1	L1175P	Neutral	0.003
NPHS1	O60500-1.1	L1175Q	Neutral	0.009
NPHS1	O60500-1.1	L1175R	Neutral	0.039
NPHS1	O60500-1.1	L1175S	Neutral	0.018
NPHS1	O60500-1.1	L1175T	Neutral	0.011
NPHS1	O60500-1.1	L1175V	Neutral	0.004
NPHS1	O60500-1.1	L1175W	Neutral	0.002
NPHS1	O60500-1.1	L1175Y	Neutral	0.003
NPHS1	O60500-1.1	Y1176A	Pathogenic	0.753
NPHS1	O60500-1.1	Y1176C	Neutral	0.433
NPHS1	O60500-1.1	Y1176D	Pathogenic	0.852
NPHS1	O60500-1.1	Y1176E	Pathogenic	0.822
NPHS1	O60500-1.1	Y1176F	Pathogenic	0.854
NPHS1	O60500-1.1	Y1176G	Pathogenic	0.835
NPHS1	O60500-1.1	Y1176H	Pathogenic	0.855
NPHS1	O60500-1.1	Y1176I	Pathogenic	0.611
NPHS1	O60500-1.1	Y1176K	Pathogenic	0.808
NPHS1	O60500-1.1	Y1176L	Pathogenic	0.574
NPHS1	O60500-1.1	Y1176M	Neutral	0.402
NPHS1	O60500-1.1	Y1176N	Pathogenic	0.856
NPHS1	O60500-1.1	Y1176P	Neutral	0.392
NPHS1	O60500-1.1	Y1176Q	Pathogenic	0.767
NPHS1	O60500-1.1	Y1176R	Pathogenic	0.815
NPHS1	O60500-1.1	Y1176S	Pathogenic	0.816
NPHS1	O60500-1.1	Y1176T	Pathogenic	0.641
NPHS1	O60500-1.1	Y1176V	Pathogenic	0.507
NPHS1	O60500-1.1	Y1176W	Pathogenic	0.919
NPHS1	O60500-1.1	D1177A	Neutral	0.021
NPHS1	O60500-1.1	D1177C	Neutral	0.025
NPHS1	O60500-1.1	D1177E	Neutral	0.022
NPHS1	O60500-1.1	D1177F	Neutral	0.174
NPHS1	O60500-1.1	D1177G	Neutral	0.031
NPHS1	O60500-1.1	D1177H	Neutral	0.026
NPHS1	O60500-1.1	D1177I	Neutral	0.143
NPHS1	O60500-1.1	D1177K	Neutral	0.014
NPHS1	O60500-1.1	D1177L	Neutral	0.087
NPHS1	O60500-1.1	D1177M	Neutral	0.066
NPHS1	O60500-1.1	D1177N	Neutral	0.012
NPHS1	O60500-1.1	D1177P	Neutral	0.033
NPHS1	O60500-1.1	D1177Q	Neutral	0.021
NPHS1	O60500-1.1	D1177R	Neutral	0.013
NPHS1	O60500-1.1	D1177S	Neutral	0.024
NPHS1	O60500-1.1	D1177T	Neutral	0.017
NPHS1	O60500-1.1	D1177V	Neutral	0.043
NPHS1	O60500-1.1	D1177W	Neutral	0.353
NPHS1	O60500-1.1	D1177Y	Neutral	0.066
NPHS1	O60500-1.1	E1178A	Neutral	0.106
NPHS1	O60500-1.1	E1178C	Neutral	0.059
NPHS1	O60500-1.1	E1178D	Neutral	0.063
NPHS1	O60500-1.1	E1178F	Neutral	0.25
NPHS1	O60500-1.1	E1178G	Neutral	0.073
NPHS1	O60500-1.1	E1178H	Neutral	0.059
NPHS1	O60500-1.1	E1178I	Neutral	0.208
NPHS1	O60500-1.1	E1178K	Neutral	0.07
NPHS1	O60500-1.1	E1178L	Neutral	0.184
NPHS1	O60500-1.1	E1178M	Neutral	0.143
NPHS1	O60500-1.1	E1178N	Neutral	0.023
NPHS1	O60500-1.1	E1178P	Neutral	0.113
NPHS1	O60500-1.1	E1178Q	Neutral	0.07
NPHS1	O60500-1.1	E1178R	Neutral	0.065
NPHS1	O60500-1.1	E1178S	Neutral	0.085
NPHS1	O60500-1.1	E1178T	Neutral	0.056
NPHS1	O60500-1.1	E1178V	Neutral	0.112
NPHS1	O60500-1.1	E1178W	Pathogenic	0.562
NPHS1	O60500-1.1	E1178Y	Neutral	0.143
NPHS1	O60500-1.1	V1179A	Neutral	0.173
NPHS1	O60500-1.1	V1179C	Neutral	0.032
NPHS1	O60500-1.1	V1179D	Neutral	0.151
NPHS1	O60500-1.1	V1179E	Neutral	0.147
NPHS1	O60500-1.1	V1179F	Neutral	0.066
NPHS1	O60500-1.1	V1179G	Neutral	0.135
NPHS1	O60500-1.1	V1179H	Neutral	0.043
NPHS1	O60500-1.1	V1179I	Neutral	0.215
NPHS1	O60500-1.1	V1179K	Neutral	0.349
NPHS1	O60500-1.1	V1179L	Neutral	0.096
NPHS1	O60500-1.1	V1179M	Neutral	0.05
NPHS1	O60500-1.1	V1179N	Neutral	0.109
NPHS1	O60500-1.1	V1179P	Neutral	0.029
NPHS1	O60500-1.1	V1179Q	Neutral	0.094
NPHS1	O60500-1.1	V1179R	Neutral	0.333
NPHS1	O60500-1.1	V1179S	Neutral	0.12
NPHS1	O60500-1.1	V1179T	Neutral	0.109
NPHS1	O60500-1.1	V1179W	Neutral	0.109
NPHS1	O60500-1.1	V1179Y	Neutral	0.048
NPHS1	O60500-1.1	E1180A	Neutral	0.049
NPHS1	O60500-1.1	E1180C	Neutral	0.026
NPHS1	O60500-1.1	E1180D	Neutral	0.028
NPHS1	O60500-1.1	E1180F	Neutral	0.125
NPHS1	O60500-1.1	E1180G	Neutral	0.033
NPHS1	O60500-1.1	E1180H	Neutral	0.026
NPHS1	O60500-1.1	E1180I	Neutral	0.101
NPHS1	O60500-1.1	E1180K	Neutral	0.031
NPHS1	O60500-1.1	E1180L	Neutral	0.088
NPHS1	O60500-1.1	E1180M	Neutral	0.067
NPHS1	O60500-1.1	E1180N	Neutral	0.01
NPHS1	O60500-1.1	E1180P	Neutral	0.052
NPHS1	O60500-1.1	E1180Q	Neutral	0.031
NPHS1	O60500-1.1	E1180R	Neutral	0.029
NPHS1	O60500-1.1	E1180S	Neutral	0.038
NPHS1	O60500-1.1	E1180T	Neutral	0.025
NPHS1	O60500-1.1	E1180V	Neutral	0.051
NPHS1	O60500-1.1	E1180W	Neutral	0.355
NPHS1	O60500-1.1	E1180Y	Neutral	0.067
NPHS1	O60500-1.1	R1181A	Neutral	0.349
NPHS1	O60500-1.1	R1181C	Neutral	0.295
NPHS1	O60500-1.1	R1181D	Neutral	0.039
NPHS1	O60500-1.1	R1181E	Neutral	0.068
NPHS1	O60500-1.1	R1181F	Neutral	0.304
NPHS1	O60500-1.1	R1181G	Neutral	0.262
NPHS1	O60500-1.1	R1181H	Neutral	0.155
NPHS1	O60500-1.1	R1181I	Neutral	0.367
NPHS1	O60500-1.1	R1181K	Neutral	0.049
NPHS1	O60500-1.1	R1181L	Neutral	0.426
NPHS1	O60500-1.1	R1181M	Neutral	0.355
NPHS1	O60500-1.1	R1181N	Neutral	0.094
NPHS1	O60500-1.1	R1181P	Neutral	0.277
NPHS1	O60500-1.1	R1181Q	Neutral	0.152
NPHS1	O60500-1.1	R1181S	Neutral	0.218
NPHS1	O60500-1.1	R1181T	Neutral	0.211
NPHS1	O60500-1.1	R1181V	Neutral	0.275
NPHS1	O60500-1.1	R1181W	Neutral	0.477
NPHS1	O60500-1.1	R1181Y	Neutral	0.142
NPHS1	O60500-1.1	T1182A	Neutral	0.0
NPHS1	O60500-1.1	T1182C	Neutral	0.0
NPHS1	O60500-1.1	T1182D	Neutral	0.0
NPHS1	O60500-1.1	T1182E	Neutral	0.0
NPHS1	O60500-1.1	T1182F	Neutral	0.0
NPHS1	O60500-1.1	T1182G	Neutral	0.0
NPHS1	O60500-1.1	T1182H	Neutral	0.0
NPHS1	O60500-1.1	T1182I	Neutral	0.0
NPHS1	O60500-1.1	T1182K	Neutral	0.0
NPHS1	O60500-1.1	T1182L	Neutral	0.0
NPHS1	O60500-1.1	T1182M	Neutral	0.0
NPHS1	O60500-1.1	T1182N	Neutral	0.0
NPHS1	O60500-1.1	T1182P	Neutral	0.0
NPHS1	O60500-1.1	T1182Q	Neutral	0.0
NPHS1	O60500-1.1	T1182R	Neutral	0.0
NPHS1	O60500-1.1	T1182S	Neutral	0.0
NPHS1	O60500-1.1	T1182V	Neutral	0.0
NPHS1	O60500-1.1	T1182W	Neutral	0.0
NPHS1	O60500-1.1	T1182Y	Neutral	0.0
NPHS1	O60500-1.1	Y1183A	Neutral	0.194
NPHS1	O60500-1.1	Y1183C	Neutral	0.057
NPHS1	O60500-1.1	Y1183D	Neutral	0.313
NPHS1	O60500-1.1	Y1183E	Neutral	0.267
NPHS1	O60500-1.1	Y1183F	Neutral	0.317
NPHS1	O60500-1.1	Y1183G	Neutral	0.286
NPHS1	O60500-1.1	Y1183H	Neutral	0.317
NPHS1	O60500-1.1	Y1183I	Neutral	0.11
NPHS1	O60500-1.1	Y1183K	Neutral	0.25
NPHS1	O60500-1.1	Y1183L	Neutral	0.096
NPHS1	O60500-1.1	Y1183M	Neutral	0.05
NPHS1	O60500-1.1	Y1183N	Neutral	0.32
NPHS1	O60500-1.1	Y1183P	Neutral	0.048
NPHS1	O60500-1.1	Y1183Q	Neutral	0.206
NPHS1	O60500-1.1	Y1183R	Neutral	0.259
NPHS1	O60500-1.1	Y1183S	Neutral	0.259
NPHS1	O60500-1.1	Y1183T	Neutral	0.123
NPHS1	O60500-1.1	Y1183V	Neutral	0.075
NPHS1	O60500-1.1	Y1183W	Neutral	0.474
NPHS1	O60500-1.1	P1184A	Neutral	0.0
NPHS1	O60500-1.1	P1184C	Neutral	0.0
NPHS1	O60500-1.1	P1184D	Neutral	0.0
NPHS1	O60500-1.1	P1184E	Neutral	0.0
NPHS1	O60500-1.1	P1184F	Neutral	0.0
NPHS1	O60500-1.1	P1184G	Neutral	0.0
NPHS1	O60500-1.1	P1184H	Neutral	0.0
NPHS1	O60500-1.1	P1184I	Neutral	0.0
NPHS1	O60500-1.1	P1184K	Neutral	0.001
NPHS1	O60500-1.1	P1184L	Neutral	0.0
NPHS1	O60500-1.1	P1184M	Neutral	0.0
NPHS1	O60500-1.1	P1184N	Neutral	0.0
NPHS1	O60500-1.1	P1184Q	Neutral	0.0
NPHS1	O60500-1.1	P1184R	Neutral	0.001
NPHS1	O60500-1.1	P1184S	Neutral	0.0
NPHS1	O60500-1.1	P1184T	Neutral	0.0
NPHS1	O60500-1.1	P1184V	Neutral	0.0
NPHS1	O60500-1.1	P1184W	Neutral	0.0
NPHS1	O60500-1.1	P1184Y	Neutral	0.0
NPHS1	O60500-1.1	P1185A	Neutral	0.003
NPHS1	O60500-1.1	P1185C	Neutral	0.001
NPHS1	O60500-1.1	P1185D	Neutral	0.008
NPHS1	O60500-1.1	P1185E	Neutral	0.01
NPHS1	O60500-1.1	P1185F	Neutral	0.004
NPHS1	O60500-1.1	P1185G	Neutral	0.004
NPHS1	O60500-1.1	P1185H	Neutral	0.003
NPHS1	O60500-1.1	P1185I	Neutral	0.004
NPHS1	O60500-1.1	P1185K	Neutral	0.03
NPHS1	O60500-1.1	P1185L	Neutral	0.004
NPHS1	O60500-1.1	P1185M	Neutral	0.003
NPHS1	O60500-1.1	P1185N	Neutral	0.005
NPHS1	O60500-1.1	P1185Q	Neutral	0.006
NPHS1	O60500-1.1	P1185R	Neutral	0.028
NPHS1	O60500-1.1	P1185S	Neutral	0.004
NPHS1	O60500-1.1	P1185T	Neutral	0.002
NPHS1	O60500-1.1	P1185V	Neutral	0.002
NPHS1	O60500-1.1	P1185W	Neutral	0.014
NPHS1	O60500-1.1	P1185Y	Neutral	0.002
NPHS1	O60500-1.1	S1186A	Neutral	0.001
NPHS1	O60500-1.1	S1186C	Neutral	0.002
NPHS1	O60500-1.1	S1186D	Neutral	0.002
NPHS1	O60500-1.1	S1186E	Neutral	0.002
NPHS1	O60500-1.1	S1186F	Neutral	0.011
NPHS1	O60500-1.1	S1186G	Neutral	0.001
NPHS1	O60500-1.1	S1186H	Neutral	0.001
NPHS1	O60500-1.1	S1186I	Neutral	0.009
NPHS1	O60500-1.1	S1186K	Neutral	0.007
NPHS1	O60500-1.1	S1186L	Neutral	0.007
NPHS1	O60500-1.1	S1186M	Neutral	0.006
NPHS1	O60500-1.1	S1186N	Neutral	0.002
NPHS1	O60500-1.1	S1186P	Neutral	0.001
NPHS1	O60500-1.1	S1186Q	Neutral	0.001
NPHS1	O60500-1.1	S1186R	Neutral	0.006
NPHS1	O60500-1.1	S1186T	Neutral	0.001
NPHS1	O60500-1.1	S1186V	Neutral	0.002
NPHS1	O60500-1.1	S1186W	Neutral	0.028
NPHS1	O60500-1.1	S1186Y	Neutral	0.004
NPHS1	O60500-1.1	G1187A	Neutral	0.001
NPHS1	O60500-1.1	G1187C	Neutral	0.001
NPHS1	O60500-1.1	G1187D	Neutral	0.002
NPHS1	O60500-1.1	G1187E	Neutral	0.002
NPHS1	O60500-1.1	G1187F	Neutral	0.014
NPHS1	O60500-1.1	G1187H	Neutral	0.001
NPHS1	O60500-1.1	G1187I	Neutral	0.007
NPHS1	O60500-1.1	G1187K	Neutral	0.006
NPHS1	O60500-1.1	G1187L	Neutral	0.006
NPHS1	O60500-1.1	G1187M	Neutral	0.005
NPHS1	O60500-1.1	G1187N	Neutral	0.003
NPHS1	O60500-1.1	G1187P	Neutral	0.001
NPHS1	O60500-1.1	G1187Q	Neutral	0.001
NPHS1	O60500-1.1	G1187R	Neutral	0.009
NPHS1	O60500-1.1	G1187S	Neutral	0.001
NPHS1	O60500-1.1	G1187T	Neutral	0.001
NPHS1	O60500-1.1	G1187V	Neutral	0.003
NPHS1	O60500-1.1	G1187W	Neutral	0.074
NPHS1	O60500-1.1	G1187Y	Neutral	0.005
NPHS1	O60500-1.1	A1188C	Neutral	0.001
NPHS1	O60500-1.1	A1188D	Neutral	0.001
NPHS1	O60500-1.1	A1188E	Neutral	0.002
NPHS1	O60500-1.1	A1188F	Neutral	0.007
NPHS1	O60500-1.1	A1188G	Neutral	0.001
NPHS1	O60500-1.1	A1188H	Neutral	0.001
NPHS1	O60500-1.1	A1188I	Neutral	0.008
NPHS1	O60500-1.1	A1188K	Neutral	0.008
NPHS1	O60500-1.1	A1188L	Neutral	0.007
NPHS1	O60500-1.1	A1188M	Neutral	0.003
NPHS1	O60500-1.1	A1188N	Neutral	0.001
NPHS1	O60500-1.1	A1188P	Neutral	0.001
NPHS1	O60500-1.1	A1188Q	Neutral	0.002
NPHS1	O60500-1.1	A1188R	Neutral	0.011
NPHS1	O60500-1.1	A1188S	Neutral	0.001
NPHS1	O60500-1.1	A1188T	Neutral	0.001
NPHS1	O60500-1.1	A1188V	Neutral	0.003
NPHS1	O60500-1.1	A1188W	Neutral	0.017
NPHS1	O60500-1.1	A1188Y	Neutral	0.002
NPHS1	O60500-1.1	W1189A	Pathogenic	0.876
NPHS1	O60500-1.1	W1189C	Pathogenic	0.711
NPHS1	O60500-1.1	W1189D	Pathogenic	0.93
NPHS1	O60500-1.1	W1189E	Pathogenic	0.914
NPHS1	O60500-1.1	W1189F	Neutral	0.435
NPHS1	O60500-1.1	W1189G	Pathogenic	0.963
NPHS1	O60500-1.1	W1189H	Pathogenic	0.803
NPHS1	O60500-1.1	W1189I	Neutral	0.165
NPHS1	O60500-1.1	W1189K	Pathogenic	0.907
NPHS1	O60500-1.1	W1189L	Neutral	0.256
NPHS1	O60500-1.1	W1189M	Pathogenic	0.507
NPHS1	O60500-1.1	W1189N	Pathogenic	0.902
NPHS1	O60500-1.1	W1189P	Pathogenic	0.598
NPHS1	O60500-1.1	W1189Q	Pathogenic	0.883
NPHS1	O60500-1.1	W1189R	Pathogenic	0.88
NPHS1	O60500-1.1	W1189S	Pathogenic	0.911
NPHS1	O60500-1.1	W1189T	Pathogenic	0.86
NPHS1	O60500-1.1	W1189V	Neutral	0.426
NPHS1	O60500-1.1	W1189Y	Pathogenic	0.774
NPHS1	O60500-1.1	G1190A	Neutral	0.009
NPHS1	O60500-1.1	G1190C	Neutral	0.011
NPHS1	O60500-1.1	G1190D	Neutral	0.02
NPHS1	O60500-1.1	G1190E	Neutral	0.017
NPHS1	O60500-1.1	G1190F	Neutral	0.107
NPHS1	O60500-1.1	G1190H	Neutral	0.01
NPHS1	O60500-1.1	G1190I	Neutral	0.059
NPHS1	O60500-1.1	G1190K	Neutral	0.051
NPHS1	O60500-1.1	G1190L	Neutral	0.051
NPHS1	O60500-1.1	G1190M	Neutral	0.039
NPHS1	O60500-1.1	G1190N	Neutral	0.026
NPHS1	O60500-1.1	G1190P	Neutral	0.012
NPHS1	O60500-1.1	G1190Q	Neutral	0.01
NPHS1	O60500-1.1	G1190R	Neutral	0.07
NPHS1	O60500-1.1	G1190S	Neutral	0.007
NPHS1	O60500-1.1	G1190T	Neutral	0.007
NPHS1	O60500-1.1	G1190V	Neutral	0.024
NPHS1	O60500-1.1	G1190W	Neutral	0.407
NPHS1	O60500-1.1	G1190Y	Neutral	0.039
NPHS1	O60500-1.1	P1191A	Neutral	0.008
NPHS1	O60500-1.1	P1191C	Neutral	0.002
NPHS1	O60500-1.1	P1191D	Neutral	0.023
NPHS1	O60500-1.1	P1191E	Neutral	0.029
NPHS1	O60500-1.1	P1191F	Neutral	0.011
NPHS1	O60500-1.1	P1191G	Neutral	0.013
NPHS1	O60500-1.1	P1191H	Neutral	0.008
NPHS1	O60500-1.1	P1191I	Neutral	0.013
NPHS1	O60500-1.1	P1191K	Neutral	0.085
NPHS1	O60500-1.1	P1191L	Neutral	0.011
NPHS1	O60500-1.1	P1191M	Neutral	0.008
NPHS1	O60500-1.1	P1191N	Neutral	0.014
NPHS1	O60500-1.1	P1191Q	Neutral	0.018
NPHS1	O60500-1.1	P1191R	Neutral	0.079
NPHS1	O60500-1.1	P1191S	Neutral	0.011
NPHS1	O60500-1.1	P1191T	Neutral	0.005
NPHS1	O60500-1.1	P1191V	Neutral	0.005
NPHS1	O60500-1.1	P1191W	Neutral	0.04
NPHS1	O60500-1.1	P1191Y	Neutral	0.005
NPHS1	O60500-1.1	L1192A	Neutral	0.109
NPHS1	O60500-1.1	L1192C	Neutral	0.028
NPHS1	O60500-1.1	L1192D	Neutral	0.094
NPHS1	O60500-1.1	L1192E	Neutral	0.077
NPHS1	O60500-1.1	L1192F	Neutral	0.009
NPHS1	O60500-1.1	L1192G	Neutral	0.084
NPHS1	O60500-1.1	L1192H	Neutral	0.021
NPHS1	O60500-1.1	L1192I	Neutral	0.015
NPHS1	O60500-1.1	L1192K	Neutral	0.16
NPHS1	O60500-1.1	L1192M	Neutral	0.026
NPHS1	O60500-1.1	L1192N	Neutral	0.097
NPHS1	O60500-1.1	L1192P	Neutral	0.017
NPHS1	O60500-1.1	L1192Q	Neutral	0.056
NPHS1	O60500-1.1	L1192R	Neutral	0.209
NPHS1	O60500-1.1	L1192S	Neutral	0.106
NPHS1	O60500-1.1	L1192T	Neutral	0.067
NPHS1	O60500-1.1	L1192V	Neutral	0.028
NPHS1	O60500-1.1	L1192W	Neutral	0.015
NPHS1	O60500-1.1	L1192Y	Neutral	0.018
NPHS1	O60500-1.1	Y1193A	Neutral	0.247
NPHS1	O60500-1.1	Y1193C	Neutral	0.076
NPHS1	O60500-1.1	Y1193D	Neutral	0.383
NPHS1	O60500-1.1	Y1193E	Neutral	0.332
NPHS1	O60500-1.1	Y1193F	Neutral	0.387
NPHS1	O60500-1.1	Y1193G	Neutral	0.353
NPHS1	O60500-1.1	Y1193H	Neutral	0.387
NPHS1	O60500-1.1	Y1193I	Neutral	0.145
NPHS1	O60500-1.1	Y1193K	Neutral	0.312
NPHS1	O60500-1.1	Y1193L	Neutral	0.127
NPHS1	O60500-1.1	Y1193M	Neutral	0.067
NPHS1	O60500-1.1	Y1193N	Neutral	0.39
NPHS1	O60500-1.1	Y1193P	Neutral	0.065
NPHS1	O60500-1.1	Y1193Q	Neutral	0.261
NPHS1	O60500-1.1	Y1193R	Neutral	0.322
NPHS1	O60500-1.1	Y1193S	Neutral	0.322
NPHS1	O60500-1.1	Y1193T	Neutral	0.161
NPHS1	O60500-1.1	Y1193V	Neutral	0.1
NPHS1	O60500-1.1	Y1193W	Pathogenic	0.551
NPHS1	O60500-1.1	D1194A	Neutral	0.01
NPHS1	O60500-1.1	D1194C	Neutral	0.011
NPHS1	O60500-1.1	D1194E	Neutral	0.01
NPHS1	O60500-1.1	D1194F	Neutral	0.087
NPHS1	O60500-1.1	D1194G	Neutral	0.014
NPHS1	O60500-1.1	D1194H	Neutral	0.012
NPHS1	O60500-1.1	D1194I	Neutral	0.07
NPHS1	O60500-1.1	D1194K	Neutral	0.007
NPHS1	O60500-1.1	D1194L	Neutral	0.042
NPHS1	O60500-1.1	D1194M	Neutral	0.031
NPHS1	O60500-1.1	D1194N	Neutral	0.005
NPHS1	O60500-1.1	D1194P	Neutral	0.015
NPHS1	O60500-1.1	D1194Q	Neutral	0.01
NPHS1	O60500-1.1	D1194R	Neutral	0.006
NPHS1	O60500-1.1	D1194S	Neutral	0.011
NPHS1	O60500-1.1	D1194T	Neutral	0.008
NPHS1	O60500-1.1	D1194V	Neutral	0.02
NPHS1	O60500-1.1	D1194W	Neutral	0.199
NPHS1	O60500-1.1	D1194Y	Neutral	0.031
NPHS1	O60500-1.1	E1195A	Neutral	0.039
NPHS1	O60500-1.1	E1195C	Neutral	0.021
NPHS1	O60500-1.1	E1195D	Neutral	0.022
NPHS1	O60500-1.1	E1195F	Neutral	0.102
NPHS1	O60500-1.1	E1195G	Neutral	0.026
NPHS1	O60500-1.1	E1195H	Neutral	0.021
NPHS1	O60500-1.1	E1195I	Neutral	0.082
NPHS1	O60500-1.1	E1195K	Neutral	0.025
NPHS1	O60500-1.1	E1195L	Neutral	0.071
NPHS1	O60500-1.1	E1195M	Neutral	0.054
NPHS1	O60500-1.1	E1195N	Neutral	0.008
NPHS1	O60500-1.1	E1195P	Neutral	0.042
NPHS1	O60500-1.1	E1195Q	Neutral	0.025
NPHS1	O60500-1.1	E1195R	Neutral	0.023
NPHS1	O60500-1.1	E1195S	Neutral	0.03
NPHS1	O60500-1.1	E1195T	Neutral	0.02
NPHS1	O60500-1.1	E1195V	Neutral	0.041
NPHS1	O60500-1.1	E1195W	Neutral	0.304
NPHS1	O60500-1.1	E1195Y	Neutral	0.054
NPHS1	O60500-1.1	V1196A	Neutral	0.024
NPHS1	O60500-1.1	V1196C	Neutral	0.004
NPHS1	O60500-1.1	V1196D	Neutral	0.02
NPHS1	O60500-1.1	V1196E	Neutral	0.02
NPHS1	O60500-1.1	V1196F	Neutral	0.008
NPHS1	O60500-1.1	V1196G	Neutral	0.018
NPHS1	O60500-1.1	V1196H	Neutral	0.005
NPHS1	O60500-1.1	V1196I	Neutral	0.031
NPHS1	O60500-1.1	V1196K	Neutral	0.059
NPHS1	O60500-1.1	V1196L	Neutral	0.012
NPHS1	O60500-1.1	V1196M	Neutral	0.006
NPHS1	O60500-1.1	V1196N	Neutral	0.014
NPHS1	O60500-1.1	V1196P	Neutral	0.003
NPHS1	O60500-1.1	V1196Q	Neutral	0.012
NPHS1	O60500-1.1	V1196R	Neutral	0.055
NPHS1	O60500-1.1	V1196S	Neutral	0.016
NPHS1	O60500-1.1	V1196T	Neutral	0.014
NPHS1	O60500-1.1	V1196W	Neutral	0.014
NPHS1	O60500-1.1	V1196Y	Neutral	0.006
NPHS1	O60500-1.1	Q1197A	Neutral	0.003
NPHS1	O60500-1.1	Q1197C	Neutral	0.002
NPHS1	O60500-1.1	Q1197D	Neutral	0.002
NPHS1	O60500-1.1	Q1197E	Neutral	0.003
NPHS1	O60500-1.1	Q1197F	Neutral	0.006
NPHS1	O60500-1.1	Q1197G	Neutral	0.002
NPHS1	O60500-1.1	Q1197H	Neutral	0.001
NPHS1	O60500-1.1	Q1197I	Neutral	0.004
NPHS1	O60500-1.1	Q1197K	Neutral	0.004
NPHS1	O60500-1.1	Q1197L	Neutral	0.006
NPHS1	O60500-1.1	Q1197M	Neutral	0.006
NPHS1	O60500-1.1	Q1197N	Neutral	0.002
NPHS1	O60500-1.1	Q1197P	Neutral	0.003
NPHS1	O60500-1.1	Q1197R	Neutral	0.006
NPHS1	O60500-1.1	Q1197S	Neutral	0.002
NPHS1	O60500-1.1	Q1197T	Neutral	0.001
NPHS1	O60500-1.1	Q1197V	Neutral	0.003
NPHS1	O60500-1.1	Q1197W	Neutral	0.032
NPHS1	O60500-1.1	Q1197Y	Neutral	0.004
NPHS1	O60500-1.1	M1198A	Neutral	0.315
NPHS1	O60500-1.1	M1198C	Neutral	0.097
NPHS1	O60500-1.1	M1198D	Neutral	0.369
NPHS1	O60500-1.1	M1198E	Neutral	0.319
NPHS1	O60500-1.1	M1198F	Neutral	0.118
NPHS1	O60500-1.1	M1198G	Neutral	0.339
NPHS1	O60500-1.1	M1198H	Neutral	0.107
NPHS1	O60500-1.1	M1198I	Neutral	0.136
NPHS1	O60500-1.1	M1198K	Pathogenic	0.517
NPHS1	O60500-1.1	M1198L	Neutral	0.168
NPHS1	O60500-1.1	M1198N	Neutral	0.376
NPHS1	O60500-1.1	M1198P	Neutral	0.089
NPHS1	O60500-1.1	M1198Q	Neutral	0.332
NPHS1	O60500-1.1	M1198R	Pathogenic	0.598
NPHS1	O60500-1.1	M1198S	Neutral	0.4
NPHS1	O60500-1.1	M1198T	Neutral	0.212
NPHS1	O60500-1.1	M1198V	Neutral	0.097
NPHS1	O60500-1.1	M1198W	Neutral	0.258
NPHS1	O60500-1.1	M1198Y	Neutral	0.064
NPHS1	O60500-1.1	G1199A	Neutral	0.0
NPHS1	O60500-1.1	G1199C	Neutral	0.0
NPHS1	O60500-1.1	G1199D	Neutral	0.0
NPHS1	O60500-1.1	G1199E	Neutral	0.0
NPHS1	O60500-1.1	G1199F	Neutral	0.002
NPHS1	O60500-1.1	G1199H	Neutral	0.0
NPHS1	O60500-1.1	G1199I	Neutral	0.001
NPHS1	O60500-1.1	G1199K	Neutral	0.001
NPHS1	O60500-1.1	G1199L	Neutral	0.001
NPHS1	O60500-1.1	G1199M	Neutral	0.001
NPHS1	O60500-1.1	G1199N	Neutral	0.0
NPHS1	O60500-1.1	G1199P	Neutral	0.0
NPHS1	O60500-1.1	G1199Q	Neutral	0.0
NPHS1	O60500-1.1	G1199R	Neutral	0.001
NPHS1	O60500-1.1	G1199S	Neutral	0.0
NPHS1	O60500-1.1	G1199T	Neutral	0.0
NPHS1	O60500-1.1	G1199V	Neutral	0.0
NPHS1	O60500-1.1	G1199W	Neutral	0.011
NPHS1	O60500-1.1	G1199Y	Neutral	0.001
NPHS1	O60500-1.1	P1200A	Neutral	0.0
NPHS1	O60500-1.1	P1200C	Neutral	0.0
NPHS1	O60500-1.1	P1200D	Neutral	0.001
NPHS1	O60500-1.1	P1200E	Neutral	0.001
NPHS1	O60500-1.1	P1200F	Neutral	0.0
NPHS1	O60500-1.1	P1200G	Neutral	0.001
NPHS1	O60500-1.1	P1200H	Neutral	0.0
NPHS1	O60500-1.1	P1200I	Neutral	0.001
NPHS1	O60500-1.1	P1200K	Neutral	0.004
NPHS1	O60500-1.1	P1200L	Neutral	0.0
NPHS1	O60500-1.1	P1200M	Neutral	0.0
NPHS1	O60500-1.1	P1200N	Neutral	0.001
NPHS1	O60500-1.1	P1200Q	Neutral	0.001
NPHS1	O60500-1.1	P1200R	Neutral	0.004
NPHS1	O60500-1.1	P1200S	Neutral	0.001
NPHS1	O60500-1.1	P1200T	Neutral	0.0
NPHS1	O60500-1.1	P1200V	Neutral	0.0
NPHS1	O60500-1.1	P1200W	Neutral	0.002
NPHS1	O60500-1.1	P1200Y	Neutral	0.0
NPHS1	O60500-1.1	W1201A	Neutral	0.003
NPHS1	O60500-1.1	W1201C	Neutral	0.001
NPHS1	O60500-1.1	W1201D	Neutral	0.006
NPHS1	O60500-1.1	W1201E	Neutral	0.004
NPHS1	O60500-1.1	W1201F	Neutral	0.0
NPHS1	O60500-1.1	W1201G	Neutral	0.011
NPHS1	O60500-1.1	W1201H	Neutral	0.002
NPHS1	O60500-1.1	W1201I	Neutral	0.0
NPHS1	O60500-1.1	W1201K	Neutral	0.004
NPHS1	O60500-1.1	W1201L	Neutral	0.0
NPHS1	O60500-1.1	W1201M	Neutral	0.0
NPHS1	O60500-1.1	W1201N	Neutral	0.004
NPHS1	O60500-1.1	W1201P	Neutral	0.001
NPHS1	O60500-1.1	W1201Q	Neutral	0.003
NPHS1	O60500-1.1	W1201R	Neutral	0.003
NPHS1	O60500-1.1	W1201S	Neutral	0.004
NPHS1	O60500-1.1	W1201T	Neutral	0.003
NPHS1	O60500-1.1	W1201V	Neutral	0.0
NPHS1	O60500-1.1	W1201Y	Neutral	0.001
NPHS1	O60500-1.1	D1202A	Neutral	0.004
NPHS1	O60500-1.1	D1202C	Neutral	0.005
NPHS1	O60500-1.1	D1202E	Neutral	0.005
NPHS1	O60500-1.1	D1202F	Neutral	0.042
NPHS1	O60500-1.1	D1202G	Neutral	0.007
NPHS1	O60500-1.1	D1202H	Neutral	0.005
NPHS1	O60500-1.1	D1202I	Neutral	0.033
NPHS1	O60500-1.1	D1202K	Neutral	0.003
NPHS1	O60500-1.1	D1202L	Neutral	0.019
NPHS1	O60500-1.1	D1202M	Neutral	0.014
NPHS1	O60500-1.1	D1202N	Neutral	0.002
NPHS1	O60500-1.1	D1202P	Neutral	0.007
NPHS1	O60500-1.1	D1202Q	Neutral	0.004
NPHS1	O60500-1.1	D1202R	Neutral	0.003
NPHS1	O60500-1.1	D1202S	Neutral	0.005
NPHS1	O60500-1.1	D1202T	Neutral	0.004
NPHS1	O60500-1.1	D1202V	Neutral	0.009
NPHS1	O60500-1.1	D1202W	Neutral	0.101
NPHS1	O60500-1.1	D1202Y	Neutral	0.014
NPHS1	O60500-1.1	L1203A	Neutral	0.0
NPHS1	O60500-1.1	L1203C	Neutral	0.0
NPHS1	O60500-1.1	L1203D	Neutral	0.0
NPHS1	O60500-1.1	L1203E	Neutral	0.0
NPHS1	O60500-1.1	L1203F	Neutral	0.0
NPHS1	O60500-1.1	L1203G	Neutral	0.0
NPHS1	O60500-1.1	L1203H	Neutral	0.0
NPHS1	O60500-1.1	L1203I	Neutral	0.0
NPHS1	O60500-1.1	L1203K	Neutral	0.0
NPHS1	O60500-1.1	L1203M	Neutral	0.0
NPHS1	O60500-1.1	L1203N	Neutral	0.0
NPHS1	O60500-1.1	L1203P	Neutral	0.0
NPHS1	O60500-1.1	L1203Q	Neutral	0.0
NPHS1	O60500-1.1	L1203R	Neutral	0.0
NPHS1	O60500-1.1	L1203S	Neutral	0.0
NPHS1	O60500-1.1	L1203T	Neutral	0.0
NPHS1	O60500-1.1	L1203V	Neutral	0.0
NPHS1	O60500-1.1	L1203W	Neutral	0.0
NPHS1	O60500-1.1	L1203Y	Neutral	0.0
NPHS1	O60500-1.1	H1204A	Neutral	0.0
NPHS1	O60500-1.1	H1204C	Neutral	0.0
NPHS1	O60500-1.1	H1204D	Neutral	0.0
NPHS1	O60500-1.1	H1204E	Neutral	0.0
NPHS1	O60500-1.1	H1204F	Neutral	0.001
NPHS1	O60500-1.1	H1204G	Neutral	0.0
NPHS1	O60500-1.1	H1204I	Neutral	0.0
NPHS1	O60500-1.1	H1204K	Neutral	0.0
NPHS1	O60500-1.1	H1204L	Neutral	0.0
NPHS1	O60500-1.1	H1204M	Neutral	0.0
NPHS1	O60500-1.1	H1204N	Neutral	0.0
NPHS1	O60500-1.1	H1204P	Neutral	0.0
NPHS1	O60500-1.1	H1204Q	Neutral	0.0
NPHS1	O60500-1.1	H1204R	Neutral	0.001
NPHS1	O60500-1.1	H1204S	Neutral	0.0
NPHS1	O60500-1.1	H1204T	Neutral	0.0
NPHS1	O60500-1.1	H1204V	Neutral	0.0
NPHS1	O60500-1.1	H1204W	Neutral	0.002
NPHS1	O60500-1.1	H1204Y	Neutral	0.001
NPHS1	O60500-1.1	W1205A	Pathogenic	0.844
NPHS1	O60500-1.1	W1205C	Pathogenic	0.653
NPHS1	O60500-1.1	W1205D	Pathogenic	0.911
NPHS1	O60500-1.1	W1205E	Pathogenic	0.891
NPHS1	O60500-1.1	W1205F	Neutral	0.372
NPHS1	O60500-1.1	W1205G	Pathogenic	0.952
NPHS1	O60500-1.1	W1205H	Pathogenic	0.758
NPHS1	O60500-1.1	W1205I	Neutral	0.132
NPHS1	O60500-1.1	W1205K	Pathogenic	0.882
NPHS1	O60500-1.1	W1205L	Neutral	0.209
NPHS1	O60500-1.1	W1205M	Neutral	0.441
NPHS1	O60500-1.1	W1205N	Pathogenic	0.876
NPHS1	O60500-1.1	W1205P	Pathogenic	0.533
NPHS1	O60500-1.1	W1205Q	Pathogenic	0.853
NPHS1	O60500-1.1	W1205R	Pathogenic	0.849
NPHS1	O60500-1.1	W1205S	Pathogenic	0.887
NPHS1	O60500-1.1	W1205T	Pathogenic	0.825
NPHS1	O60500-1.1	W1205V	Neutral	0.363
NPHS1	O60500-1.1	W1205Y	Pathogenic	0.724
NPHS1	O60500-1.1	P1206A	Neutral	0.001
NPHS1	O60500-1.1	P1206C	Neutral	0.0
NPHS1	O60500-1.1	P1206D	Neutral	0.003
NPHS1	O60500-1.1	P1206E	Neutral	0.004
NPHS1	O60500-1.1	P1206F	Neutral	0.001
NPHS1	O60500-1.1	P1206G	Neutral	0.002
NPHS1	O60500-1.1	P1206H	Neutral	0.001
NPHS1	O60500-1.1	P1206I	Neutral	0.002
NPHS1	O60500-1.1	P1206K	Neutral	0.011
NPHS1	O60500-1.1	P1206L	Neutral	0.001
NPHS1	O60500-1.1	P1206M	Neutral	0.001
NPHS1	O60500-1.1	P1206N	Neutral	0.002
NPHS1	O60500-1.1	P1206Q	Neutral	0.002
NPHS1	O60500-1.1	P1206R	Neutral	0.01
NPHS1	O60500-1.1	P1206S	Neutral	0.001
NPHS1	O60500-1.1	P1206T	Neutral	0.001
NPHS1	O60500-1.1	P1206V	Neutral	0.001
NPHS1	O60500-1.1	P1206W	Neutral	0.005
NPHS1	O60500-1.1	P1206Y	Neutral	0.001
NPHS1	O60500-1.1	E1207A	Neutral	0.003
NPHS1	O60500-1.1	E1207C	Neutral	0.001
NPHS1	O60500-1.1	E1207D	Neutral	0.002
NPHS1	O60500-1.1	E1207F	Neutral	0.008
NPHS1	O60500-1.1	E1207G	Neutral	0.002
NPHS1	O60500-1.1	E1207H	Neutral	0.001
NPHS1	O60500-1.1	E1207I	Neutral	0.006
NPHS1	O60500-1.1	E1207K	Neutral	0.002
NPHS1	O60500-1.1	E1207L	Neutral	0.005
NPHS1	O60500-1.1	E1207M	Neutral	0.004
NPHS1	O60500-1.1	E1207N	Neutral	0.001
NPHS1	O60500-1.1	E1207P	Neutral	0.003
NPHS1	O60500-1.1	E1207Q	Neutral	0.002
NPHS1	O60500-1.1	E1207R	Neutral	0.002
NPHS1	O60500-1.1	E1207S	Neutral	0.002
NPHS1	O60500-1.1	E1207T	Neutral	0.001
NPHS1	O60500-1.1	E1207V	Neutral	0.003
NPHS1	O60500-1.1	E1207W	Neutral	0.029
NPHS1	O60500-1.1	E1207Y	Neutral	0.004
NPHS1	O60500-1.1	D1208A	Neutral	0.001
NPHS1	O60500-1.1	D1208C	Neutral	0.001
NPHS1	O60500-1.1	D1208E	Neutral	0.001
NPHS1	O60500-1.1	D1208F	Neutral	0.011
NPHS1	O60500-1.1	D1208G	Neutral	0.002
NPHS1	O60500-1.1	D1208H	Neutral	0.001
NPHS1	O60500-1.1	D1208I	Neutral	0.008
NPHS1	O60500-1.1	D1208K	Neutral	0.001
NPHS1	O60500-1.1	D1208L	Neutral	0.005
NPHS1	O60500-1.1	D1208M	Neutral	0.004
NPHS1	O60500-1.1	D1208N	Neutral	0.001
NPHS1	O60500-1.1	D1208P	Neutral	0.002
NPHS1	O60500-1.1	D1208Q	Neutral	0.001
NPHS1	O60500-1.1	D1208R	Neutral	0.001
NPHS1	O60500-1.1	D1208S	Neutral	0.001
NPHS1	O60500-1.1	D1208T	Neutral	0.001
NPHS1	O60500-1.1	D1208V	Neutral	0.002
NPHS1	O60500-1.1	D1208W	Neutral	0.027
NPHS1	O60500-1.1	D1208Y	Neutral	0.004
NPHS1	O60500-1.1	T1209A	Neutral	0.0
NPHS1	O60500-1.1	T1209C	Neutral	0.0
NPHS1	O60500-1.1	T1209D	Neutral	0.0
NPHS1	O60500-1.1	T1209E	Neutral	0.0
NPHS1	O60500-1.1	T1209F	Neutral	0.0
NPHS1	O60500-1.1	T1209G	Neutral	0.0
NPHS1	O60500-1.1	T1209H	Neutral	0.0
NPHS1	O60500-1.1	T1209I	Neutral	0.001
NPHS1	O60500-1.1	T1209K	Neutral	0.0
NPHS1	O60500-1.1	T1209L	Neutral	0.0
NPHS1	O60500-1.1	T1209M	Neutral	0.0
NPHS1	O60500-1.1	T1209N	Neutral	0.0
NPHS1	O60500-1.1	T1209P	Neutral	0.0
NPHS1	O60500-1.1	T1209Q	Neutral	0.0
NPHS1	O60500-1.1	T1209R	Neutral	0.001
NPHS1	O60500-1.1	T1209S	Neutral	0.0
NPHS1	O60500-1.1	T1209V	Neutral	0.0
NPHS1	O60500-1.1	T1209W	Neutral	0.002
NPHS1	O60500-1.1	T1209Y	Neutral	0.0
NPHS1	O60500-1.1	Y1210A	Neutral	0.268
NPHS1	O60500-1.1	Y1210C	Neutral	0.084
NPHS1	O60500-1.1	Y1210D	Neutral	0.409
NPHS1	O60500-1.1	Y1210E	Neutral	0.357
NPHS1	O60500-1.1	Y1210F	Neutral	0.413
NPHS1	O60500-1.1	Y1210G	Neutral	0.378
NPHS1	O60500-1.1	Y1210H	Neutral	0.413
NPHS1	O60500-1.1	Y1210I	Neutral	0.159
NPHS1	O60500-1.1	Y1210K	Neutral	0.336
NPHS1	O60500-1.1	Y1210L	Neutral	0.139
NPHS1	O60500-1.1	Y1210M	Neutral	0.074
NPHS1	O60500-1.1	Y1210N	Neutral	0.416
NPHS1	O60500-1.1	Y1210P	Neutral	0.072
NPHS1	O60500-1.1	Y1210Q	Neutral	0.283
NPHS1	O60500-1.1	Y1210R	Neutral	0.346
NPHS1	O60500-1.1	Y1210S	Neutral	0.347
NPHS1	O60500-1.1	Y1210T	Neutral	0.176
NPHS1	O60500-1.1	Y1210V	Neutral	0.11
NPHS1	O60500-1.1	Y1210W	Pathogenic	0.578
NPHS1	O60500-1.1	Q1211A	Neutral	0.001
NPHS1	O60500-1.1	Q1211C	Neutral	0.001
NPHS1	O60500-1.1	Q1211D	Neutral	0.001
NPHS1	O60500-1.1	Q1211E	Neutral	0.002
NPHS1	O60500-1.1	Q1211F	Neutral	0.003
NPHS1	O60500-1.1	Q1211G	Neutral	0.001
NPHS1	O60500-1.1	Q1211H	Neutral	0.001
NPHS1	O60500-1.1	Q1211I	Neutral	0.003
NPHS1	O60500-1.1	Q1211K	Neutral	0.003
NPHS1	O60500-1.1	Q1211L	Neutral	0.003
NPHS1	O60500-1.1	Q1211M	Neutral	0.004
NPHS1	O60500-1.1	Q1211N	Neutral	0.001
NPHS1	O60500-1.1	Q1211P	Neutral	0.002
NPHS1	O60500-1.1	Q1211R	Neutral	0.004
NPHS1	O60500-1.1	Q1211S	Neutral	0.001
NPHS1	O60500-1.1	Q1211T	Neutral	0.001
NPHS1	O60500-1.1	Q1211V	Neutral	0.002
NPHS1	O60500-1.1	Q1211W	Neutral	0.018
NPHS1	O60500-1.1	Q1211Y	Neutral	0.002
NPHS1	O60500-1.1	D1212A	Neutral	0.055
NPHS1	O60500-1.1	D1212C	Neutral	0.063
NPHS1	O60500-1.1	D1212E	Neutral	0.057
NPHS1	O60500-1.1	D1212F	Neutral	0.36
NPHS1	O60500-1.1	D1212G	Neutral	0.079
NPHS1	O60500-1.1	D1212H	Neutral	0.066
NPHS1	O60500-1.1	D1212I	Neutral	0.307
NPHS1	O60500-1.1	D1212K	Neutral	0.037
NPHS1	O60500-1.1	D1212L	Neutral	0.203
NPHS1	O60500-1.1	D1212M	Neutral	0.159
NPHS1	O60500-1.1	D1212N	Neutral	0.031
NPHS1	O60500-1.1	D1212P	Neutral	0.084
NPHS1	O60500-1.1	D1212Q	Neutral	0.054
NPHS1	O60500-1.1	D1212R	Neutral	0.035
NPHS1	O60500-1.1	D1212S	Neutral	0.063
NPHS1	O60500-1.1	D1212T	Neutral	0.045
NPHS1	O60500-1.1	D1212V	Neutral	0.106
NPHS1	O60500-1.1	D1212W	Pathogenic	0.592
NPHS1	O60500-1.1	D1212Y	Neutral	0.159
NPHS1	O60500-1.1	P1213A	Neutral	0.002
NPHS1	O60500-1.1	P1213C	Neutral	0.0
NPHS1	O60500-1.1	P1213D	Neutral	0.005
NPHS1	O60500-1.1	P1213E	Neutral	0.007
NPHS1	O60500-1.1	P1213F	Neutral	0.003
NPHS1	O60500-1.1	P1213G	Neutral	0.003
NPHS1	O60500-1.1	P1213H	Neutral	0.002
NPHS1	O60500-1.1	P1213I	Neutral	0.003
NPHS1	O60500-1.1	P1213K	Neutral	0.021
NPHS1	O60500-1.1	P1213L	Neutral	0.003
NPHS1	O60500-1.1	P1213M	Neutral	0.002
NPHS1	O60500-1.1	P1213N	Neutral	0.003
NPHS1	O60500-1.1	P1213Q	Neutral	0.004
NPHS1	O60500-1.1	P1213R	Neutral	0.02
NPHS1	O60500-1.1	P1213S	Neutral	0.003
NPHS1	O60500-1.1	P1213T	Neutral	0.001
NPHS1	O60500-1.1	P1213V	Neutral	0.001
NPHS1	O60500-1.1	P1213W	Neutral	0.01
NPHS1	O60500-1.1	P1213Y	Neutral	0.001
NPHS1	O60500-1.1	R1214A	Neutral	0.033
NPHS1	O60500-1.1	R1214C	Neutral	0.026
NPHS1	O60500-1.1	R1214D	Neutral	0.003
NPHS1	O60500-1.1	R1214E	Neutral	0.005
NPHS1	O60500-1.1	R1214F	Neutral	0.027
NPHS1	O60500-1.1	R1214G	Neutral	0.022
NPHS1	O60500-1.1	R1214H	Neutral	0.012
NPHS1	O60500-1.1	R1214I	Neutral	0.036
NPHS1	O60500-1.1	R1214K	Neutral	0.003
NPHS1	O60500-1.1	R1214L	Neutral	0.045
NPHS1	O60500-1.1	R1214M	Neutral	0.034
NPHS1	O60500-1.1	R1214N	Neutral	0.007
NPHS1	O60500-1.1	R1214P	Neutral	0.024
NPHS1	O60500-1.1	R1214Q	Neutral	0.011
NPHS1	O60500-1.1	R1214S	Neutral	0.018
NPHS1	O60500-1.1	R1214T	Neutral	0.017
NPHS1	O60500-1.1	R1214V	Neutral	0.024
NPHS1	O60500-1.1	R1214W	Neutral	0.055
NPHS1	O60500-1.1	R1214Y	Neutral	0.01
NPHS1	O60500-1.1	G1215A	Neutral	0.01
NPHS1	O60500-1.1	G1215C	Neutral	0.013
NPHS1	O60500-1.1	G1215D	Neutral	0.023
NPHS1	O60500-1.1	G1215E	Neutral	0.019
NPHS1	O60500-1.1	G1215F	Neutral	0.118
NPHS1	O60500-1.1	G1215H	Neutral	0.011
NPHS1	O60500-1.1	G1215I	Neutral	0.066
NPHS1	O60500-1.1	G1215K	Neutral	0.057
NPHS1	O60500-1.1	G1215L	Neutral	0.057
NPHS1	O60500-1.1	G1215M	Neutral	0.043
NPHS1	O60500-1.1	G1215N	Neutral	0.029
NPHS1	O60500-1.1	G1215P	Neutral	0.014
NPHS1	O60500-1.1	G1215Q	Neutral	0.012
NPHS1	O60500-1.1	G1215R	Neutral	0.078
NPHS1	O60500-1.1	G1215S	Neutral	0.008
NPHS1	O60500-1.1	G1215T	Neutral	0.008
NPHS1	O60500-1.1	G1215V	Neutral	0.027
NPHS1	O60500-1.1	G1215W	Neutral	0.435
NPHS1	O60500-1.1	G1215Y	Neutral	0.043
NPHS1	O60500-1.1	I1216A	Neutral	0.203
NPHS1	O60500-1.1	I1216C	Neutral	0.056
NPHS1	O60500-1.1	I1216D	Neutral	0.244
NPHS1	O60500-1.1	I1216E	Neutral	0.148
NPHS1	O60500-1.1	I1216F	Neutral	0.014
NPHS1	O60500-1.1	I1216G	Neutral	0.16
NPHS1	O60500-1.1	I1216H	Neutral	0.043
NPHS1	O60500-1.1	I1216K	Neutral	0.21
NPHS1	O60500-1.1	I1216L	Neutral	0.027
NPHS1	O60500-1.1	I1216M	Neutral	0.036
NPHS1	O60500-1.1	I1216N	Neutral	0.182
NPHS1	O60500-1.1	I1216P	Neutral	0.035
NPHS1	O60500-1.1	I1216Q	Neutral	0.076
NPHS1	O60500-1.1	I1216R	Neutral	0.27
NPHS1	O60500-1.1	I1216S	Neutral	0.198
NPHS1	O60500-1.1	I1216T	Neutral	0.129
NPHS1	O60500-1.1	I1216V	Neutral	0.117
NPHS1	O60500-1.1	I1216W	Neutral	0.015
NPHS1	O60500-1.1	I1216Y	Neutral	0.036
NPHS1	O60500-1.1	Y1217A	Neutral	0.41
NPHS1	O60500-1.1	Y1217C	Neutral	0.148
NPHS1	O60500-1.1	Y1217D	Pathogenic	0.568
NPHS1	O60500-1.1	Y1217E	Pathogenic	0.513
NPHS1	O60500-1.1	Y1217F	Pathogenic	0.572
NPHS1	O60500-1.1	Y1217G	Pathogenic	0.536
NPHS1	O60500-1.1	Y1217H	Pathogenic	0.572
NPHS1	O60500-1.1	Y1217I	Neutral	0.263
NPHS1	O60500-1.1	Y1217K	Neutral	0.49
NPHS1	O60500-1.1	Y1217L	Neutral	0.235
NPHS1	O60500-1.1	Y1217M	Neutral	0.132
NPHS1	O60500-1.1	Y1217N	Pathogenic	0.575
NPHS1	O60500-1.1	Y1217P	Neutral	0.128
NPHS1	O60500-1.1	Y1217Q	Neutral	0.428
NPHS1	O60500-1.1	Y1217R	Pathogenic	0.501
NPHS1	O60500-1.1	Y1217S	Pathogenic	0.502
NPHS1	O60500-1.1	Y1217T	Neutral	0.288
NPHS1	O60500-1.1	Y1217V	Neutral	0.19
NPHS1	O60500-1.1	Y1217W	Pathogenic	0.722
NPHS1	O60500-1.1	D1218A	Neutral	0.084
NPHS1	O60500-1.1	D1218C	Neutral	0.097
NPHS1	O60500-1.1	D1218E	Neutral	0.088
NPHS1	O60500-1.1	D1218F	Neutral	0.473
NPHS1	O60500-1.1	D1218G	Neutral	0.12
NPHS1	O60500-1.1	D1218H	Neutral	0.102
NPHS1	O60500-1.1	D1218I	Neutral	0.415
NPHS1	O60500-1.1	D1218K	Neutral	0.058
NPHS1	O60500-1.1	D1218L	Neutral	0.29
NPHS1	O60500-1.1	D1218M	Neutral	0.232
NPHS1	O60500-1.1	D1218N	Neutral	0.048
NPHS1	O60500-1.1	D1218P	Neutral	0.128
NPHS1	O60500-1.1	D1218Q	Neutral	0.084
NPHS1	O60500-1.1	D1218R	Neutral	0.054
NPHS1	O60500-1.1	D1218S	Neutral	0.096
NPHS1	O60500-1.1	D1218T	Neutral	0.07
NPHS1	O60500-1.1	D1218V	Neutral	0.159
NPHS1	O60500-1.1	D1218W	Pathogenic	0.699
NPHS1	O60500-1.1	D1218Y	Neutral	0.232
NPHS1	O60500-1.1	Q1219A	Neutral	0.011
NPHS1	O60500-1.1	Q1219C	Neutral	0.009
NPHS1	O60500-1.1	Q1219D	Neutral	0.01
NPHS1	O60500-1.1	Q1219E	Neutral	0.012
NPHS1	O60500-1.1	Q1219F	Neutral	0.025
NPHS1	O60500-1.1	Q1219G	Neutral	0.008
NPHS1	O60500-1.1	Q1219H	Neutral	0.005
NPHS1	O60500-1.1	Q1219I	Neutral	0.02
NPHS1	O60500-1.1	Q1219K	Neutral	0.02
NPHS1	O60500-1.1	Q1219L	Neutral	0.025
NPHS1	O60500-1.1	Q1219M	Neutral	0.028
NPHS1	O60500-1.1	Q1219N	Neutral	0.007
NPHS1	O60500-1.1	Q1219P	Neutral	0.012
NPHS1	O60500-1.1	Q1219R	Neutral	0.027
NPHS1	O60500-1.1	Q1219S	Neutral	0.009
NPHS1	O60500-1.1	Q1219T	Neutral	0.006
NPHS1	O60500-1.1	Q1219V	Neutral	0.012
NPHS1	O60500-1.1	Q1219W	Neutral	0.128
NPHS1	O60500-1.1	Q1219Y	Neutral	0.019
NPHS1	O60500-1.1	V1220A	Neutral	0.054
NPHS1	O60500-1.1	V1220C	Neutral	0.009
NPHS1	O60500-1.1	V1220D	Neutral	0.046
NPHS1	O60500-1.1	V1220E	Neutral	0.045
NPHS1	O60500-1.1	V1220F	Neutral	0.019
NPHS1	O60500-1.1	V1220G	Neutral	0.041
NPHS1	O60500-1.1	V1220H	Neutral	0.012
NPHS1	O60500-1.1	V1220I	Neutral	0.069
NPHS1	O60500-1.1	V1220K	Neutral	0.128
NPHS1	O60500-1.1	V1220L	Neutral	0.028
NPHS1	O60500-1.1	V1220M	Neutral	0.014
NPHS1	O60500-1.1	V1220N	Neutral	0.032
NPHS1	O60500-1.1	V1220P	Neutral	0.008
NPHS1	O60500-1.1	V1220Q	Neutral	0.028
NPHS1	O60500-1.1	V1220R	Neutral	0.12
NPHS1	O60500-1.1	V1220S	Neutral	0.036
NPHS1	O60500-1.1	V1220T	Neutral	0.032
NPHS1	O60500-1.1	V1220W	Neutral	0.032
NPHS1	O60500-1.1	V1220Y	Neutral	0.014
NPHS1	O60500-1.1	A1221C	Neutral	0.008
NPHS1	O60500-1.1	A1221D	Neutral	0.008
NPHS1	O60500-1.1	A1221E	Neutral	0.014
NPHS1	O60500-1.1	A1221F	Neutral	0.038
NPHS1	O60500-1.1	A1221G	Neutral	0.005
NPHS1	O60500-1.1	A1221H	Neutral	0.004
NPHS1	O60500-1.1	A1221I	Neutral	0.045
NPHS1	O60500-1.1	A1221K	Neutral	0.043
NPHS1	O60500-1.1	A1221L	Neutral	0.039
NPHS1	O60500-1.1	A1221M	Neutral	0.02
NPHS1	O60500-1.1	A1221N	Neutral	0.007
NPHS1	O60500-1.1	A1221P	Neutral	0.004
NPHS1	O60500-1.1	A1221Q	Neutral	0.009
NPHS1	O60500-1.1	A1221R	Neutral	0.059
NPHS1	O60500-1.1	A1221S	Neutral	0.006
NPHS1	O60500-1.1	A1221T	Neutral	0.004
NPHS1	O60500-1.1	A1221V	Neutral	0.018
NPHS1	O60500-1.1	A1221W	Neutral	0.094
NPHS1	O60500-1.1	A1221Y	Neutral	0.013
NPHS1	O60500-1.1	G1222A	Neutral	0.001
NPHS1	O60500-1.1	G1222C	Neutral	0.001
NPHS1	O60500-1.1	G1222D	Neutral	0.002
NPHS1	O60500-1.1	G1222E	Neutral	0.001
NPHS1	O60500-1.1	G1222F	Neutral	0.009
NPHS1	O60500-1.1	G1222H	Neutral	0.001
NPHS1	O60500-1.1	G1222I	Neutral	0.005
NPHS1	O60500-1.1	G1222K	Neutral	0.004
NPHS1	O60500-1.1	G1222L	Neutral	0.004
NPHS1	O60500-1.1	G1222M	Neutral	0.003
NPHS1	O60500-1.1	G1222N	Neutral	0.002
NPHS1	O60500-1.1	G1222P	Neutral	0.001
NPHS1	O60500-1.1	G1222Q	Neutral	0.001
NPHS1	O60500-1.1	G1222R	Neutral	0.006
NPHS1	O60500-1.1	G1222S	Neutral	0.001
NPHS1	O60500-1.1	G1222T	Neutral	0.001
NPHS1	O60500-1.1	G1222V	Neutral	0.002
NPHS1	O60500-1.1	G1222W	Neutral	0.051
NPHS1	O60500-1.1	G1222Y	Neutral	0.003
NPHS1	O60500-1.1	D1223A	Neutral	0.012
NPHS1	O60500-1.1	D1223C	Neutral	0.014
NPHS1	O60500-1.1	D1223E	Neutral	0.013
NPHS1	O60500-1.1	D1223F	Neutral	0.105
NPHS1	O60500-1.1	D1223G	Neutral	0.017
NPHS1	O60500-1.1	D1223H	Neutral	0.015
NPHS1	O60500-1.1	D1223I	Neutral	0.085
NPHS1	O60500-1.1	D1223K	Neutral	0.008
NPHS1	O60500-1.1	D1223L	Neutral	0.051
NPHS1	O60500-1.1	D1223M	Neutral	0.038
NPHS1	O60500-1.1	D1223N	Neutral	0.007
NPHS1	O60500-1.1	D1223P	Neutral	0.019
NPHS1	O60500-1.1	D1223Q	Neutral	0.012
NPHS1	O60500-1.1	D1223R	Neutral	0.007
NPHS1	O60500-1.1	D1223S	Neutral	0.014
NPHS1	O60500-1.1	D1223T	Neutral	0.01
NPHS1	O60500-1.1	D1223V	Neutral	0.024
NPHS1	O60500-1.1	D1223W	Neutral	0.233
NPHS1	O60500-1.1	D1223Y	Neutral	0.038
NPHS1	O60500-1.1	L1224A	Neutral	0.004
NPHS1	O60500-1.1	L1224C	Neutral	0.001
NPHS1	O60500-1.1	L1224D	Neutral	0.003
NPHS1	O60500-1.1	L1224E	Neutral	0.003
NPHS1	O60500-1.1	L1224F	Neutral	0.0
NPHS1	O60500-1.1	L1224G	Neutral	0.003
NPHS1	O60500-1.1	L1224H	Neutral	0.001
NPHS1	O60500-1.1	L1224I	Neutral	0.001
NPHS1	O60500-1.1	L1224K	Neutral	0.006
NPHS1	O60500-1.1	L1224M	Neutral	0.001
NPHS1	O60500-1.1	L1224N	Neutral	0.004
NPHS1	O60500-1.1	L1224P	Neutral	0.001
NPHS1	O60500-1.1	L1224Q	Neutral	0.002
NPHS1	O60500-1.1	L1224R	Neutral	0.009
NPHS1	O60500-1.1	L1224S	Neutral	0.004
NPHS1	O60500-1.1	L1224T	Neutral	0.002
NPHS1	O60500-1.1	L1224V	Neutral	0.001
NPHS1	O60500-1.1	L1224W	Neutral	0.001
NPHS1	O60500-1.1	L1224Y	Neutral	0.001
NPHS1	O60500-1.1	D1225A	Neutral	0.002
NPHS1	O60500-1.1	D1225C	Neutral	0.003
NPHS1	O60500-1.1	D1225E	Neutral	0.002
NPHS1	O60500-1.1	D1225F	Neutral	0.021
NPHS1	O60500-1.1	D1225G	Neutral	0.003
NPHS1	O60500-1.1	D1225H	Neutral	0.003
NPHS1	O60500-1.1	D1225I	Neutral	0.016
NPHS1	O60500-1.1	D1225K	Neutral	0.001
NPHS1	O60500-1.1	D1225L	Neutral	0.01
NPHS1	O60500-1.1	D1225M	Neutral	0.007
NPHS1	O60500-1.1	D1225N	Neutral	0.001
NPHS1	O60500-1.1	D1225P	Neutral	0.003
NPHS1	O60500-1.1	D1225Q	Neutral	0.002
NPHS1	O60500-1.1	D1225R	Neutral	0.001
NPHS1	O60500-1.1	D1225S	Neutral	0.003
NPHS1	O60500-1.1	D1225T	Neutral	0.002
NPHS1	O60500-1.1	D1225V	Neutral	0.004
NPHS1	O60500-1.1	D1225W	Neutral	0.052
NPHS1	O60500-1.1	D1225Y	Neutral	0.007
NPHS1	O60500-1.1	T1226A	Neutral	0.0
NPHS1	O60500-1.1	T1226C	Neutral	0.0
NPHS1	O60500-1.1	T1226D	Neutral	0.0
NPHS1	O60500-1.1	T1226E	Neutral	0.0
NPHS1	O60500-1.1	T1226F	Neutral	0.0
NPHS1	O60500-1.1	T1226G	Neutral	0.0
NPHS1	O60500-1.1	T1226H	Neutral	0.0
NPHS1	O60500-1.1	T1226I	Neutral	0.0
NPHS1	O60500-1.1	T1226K	Neutral	0.0
NPHS1	O60500-1.1	T1226L	Neutral	0.0
NPHS1	O60500-1.1	T1226M	Neutral	0.0
NPHS1	O60500-1.1	T1226N	Neutral	0.0
NPHS1	O60500-1.1	T1226P	Neutral	0.0
NPHS1	O60500-1.1	T1226Q	Neutral	0.0
NPHS1	O60500-1.1	T1226R	Neutral	0.0
NPHS1	O60500-1.1	T1226S	Neutral	0.0
NPHS1	O60500-1.1	T1226V	Neutral	0.0
NPHS1	O60500-1.1	T1226W	Neutral	0.001
NPHS1	O60500-1.1	T1226Y	Neutral	0.0
NPHS1	O60500-1.1	L1227A	Neutral	0.0
NPHS1	O60500-1.1	L1227C	Neutral	0.0
NPHS1	O60500-1.1	L1227D	Neutral	0.0
NPHS1	O60500-1.1	L1227E	Neutral	0.0
NPHS1	O60500-1.1	L1227F	Neutral	0.0
NPHS1	O60500-1.1	L1227G	Neutral	0.0
NPHS1	O60500-1.1	L1227H	Neutral	0.0
NPHS1	O60500-1.1	L1227I	Neutral	0.0
NPHS1	O60500-1.1	L1227K	Neutral	0.0
NPHS1	O60500-1.1	L1227M	Neutral	0.0
NPHS1	O60500-1.1	L1227N	Neutral	0.0
NPHS1	O60500-1.1	L1227P	Neutral	0.0
NPHS1	O60500-1.1	L1227Q	Neutral	0.0
NPHS1	O60500-1.1	L1227R	Neutral	0.0
NPHS1	O60500-1.1	L1227S	Neutral	0.0
NPHS1	O60500-1.1	L1227T	Neutral	0.0
NPHS1	O60500-1.1	L1227V	Neutral	0.0
NPHS1	O60500-1.1	L1227W	Neutral	0.0
NPHS1	O60500-1.1	L1227Y	Neutral	0.0
NPHS1	O60500-1.1	E1228A	Neutral	0.005
NPHS1	O60500-1.1	E1228C	Neutral	0.003
NPHS1	O60500-1.1	E1228D	Neutral	0.003
NPHS1	O60500-1.1	E1228F	Neutral	0.015
NPHS1	O60500-1.1	E1228G	Neutral	0.004
NPHS1	O60500-1.1	E1228H	Neutral	0.003
NPHS1	O60500-1.1	E1228I	Neutral	0.012
NPHS1	O60500-1.1	E1228K	Neutral	0.003
NPHS1	O60500-1.1	E1228L	Neutral	0.01
NPHS1	O60500-1.1	E1228M	Neutral	0.008
NPHS1	O60500-1.1	E1228N	Neutral	0.001
NPHS1	O60500-1.1	E1228P	Neutral	0.006
NPHS1	O60500-1.1	E1228Q	Neutral	0.003
NPHS1	O60500-1.1	E1228R	Neutral	0.003
NPHS1	O60500-1.1	E1228S	Neutral	0.004
NPHS1	O60500-1.1	E1228T	Neutral	0.003
NPHS1	O60500-1.1	E1228V	Neutral	0.006
NPHS1	O60500-1.1	E1228W	Neutral	0.056
NPHS1	O60500-1.1	E1228Y	Neutral	0.008
NPHS1	O60500-1.1	P1229A	Neutral	0.0
NPHS1	O60500-1.1	P1229C	Neutral	0.0
NPHS1	O60500-1.1	P1229D	Neutral	0.001
NPHS1	O60500-1.1	P1229E	Neutral	0.001
NPHS1	O60500-1.1	P1229F	Neutral	0.001
NPHS1	O60500-1.1	P1229G	Neutral	0.001
NPHS1	O60500-1.1	P1229H	Neutral	0.0
NPHS1	O60500-1.1	P1229I	Neutral	0.001
NPHS1	O60500-1.1	P1229K	Neutral	0.005
NPHS1	O60500-1.1	P1229L	Neutral	0.001
NPHS1	O60500-1.1	P1229M	Neutral	0.0
NPHS1	O60500-1.1	P1229N	Neutral	0.001
NPHS1	O60500-1.1	P1229Q	Neutral	0.001
NPHS1	O60500-1.1	P1229R	Neutral	0.004
NPHS1	O60500-1.1	P1229S	Neutral	0.001
NPHS1	O60500-1.1	P1229T	Neutral	0.0
NPHS1	O60500-1.1	P1229V	Neutral	0.0
NPHS1	O60500-1.1	P1229W	Neutral	0.002
NPHS1	O60500-1.1	P1229Y	Neutral	0.0
NPHS1	O60500-1.1	D1230A	Neutral	0.006
NPHS1	O60500-1.1	D1230C	Neutral	0.007
NPHS1	O60500-1.1	D1230E	Neutral	0.006
NPHS1	O60500-1.1	D1230F	Neutral	0.053
NPHS1	O60500-1.1	D1230G	Neutral	0.008
NPHS1	O60500-1.1	D1230H	Neutral	0.007
NPHS1	O60500-1.1	D1230I	Neutral	0.043
NPHS1	O60500-1.1	D1230K	Neutral	0.004
NPHS1	O60500-1.1	D1230L	Neutral	0.025
NPHS1	O60500-1.1	D1230M	Neutral	0.019
NPHS1	O60500-1.1	D1230N	Neutral	0.003
NPHS1	O60500-1.1	D1230P	Neutral	0.009
NPHS1	O60500-1.1	D1230Q	Neutral	0.006
NPHS1	O60500-1.1	D1230R	Neutral	0.004
NPHS1	O60500-1.1	D1230S	Neutral	0.007
NPHS1	O60500-1.1	D1230T	Neutral	0.005
NPHS1	O60500-1.1	D1230V	Neutral	0.012
NPHS1	O60500-1.1	D1230W	Neutral	0.127
NPHS1	O60500-1.1	D1230Y	Neutral	0.019
NPHS1	O60500-1.1	S1231A	Neutral	0.001
NPHS1	O60500-1.1	S1231C	Neutral	0.001
NPHS1	O60500-1.1	S1231D	Neutral	0.001
NPHS1	O60500-1.1	S1231E	Neutral	0.002
NPHS1	O60500-1.1	S1231F	Neutral	0.008
NPHS1	O60500-1.1	S1231G	Neutral	0.001
NPHS1	O60500-1.1	S1231H	Neutral	0.001
NPHS1	O60500-1.1	S1231I	Neutral	0.006
NPHS1	O60500-1.1	S1231K	Neutral	0.005
NPHS1	O60500-1.1	S1231L	Neutral	0.005
NPHS1	O60500-1.1	S1231M	Neutral	0.004
NPHS1	O60500-1.1	S1231N	Neutral	0.002
NPHS1	O60500-1.1	S1231P	Neutral	0.001
NPHS1	O60500-1.1	S1231Q	Neutral	0.001
NPHS1	O60500-1.1	S1231R	Neutral	0.004
NPHS1	O60500-1.1	S1231T	Neutral	0.001
NPHS1	O60500-1.1	S1231V	Neutral	0.002
NPHS1	O60500-1.1	S1231W	Neutral	0.02
NPHS1	O60500-1.1	S1231Y	Neutral	0.003
NPHS1	O60500-1.1	L1232A	Neutral	0.097
NPHS1	O60500-1.1	L1232C	Neutral	0.024
NPHS1	O60500-1.1	L1232D	Neutral	0.083
NPHS1	O60500-1.1	L1232E	Neutral	0.068
NPHS1	O60500-1.1	L1232F	Neutral	0.008
NPHS1	O60500-1.1	L1232G	Neutral	0.074
NPHS1	O60500-1.1	L1232H	Neutral	0.018
NPHS1	O60500-1.1	L1232I	Neutral	0.013
NPHS1	O60500-1.1	L1232K	Neutral	0.143
NPHS1	O60500-1.1	L1232M	Neutral	0.023
NPHS1	O60500-1.1	L1232N	Neutral	0.086
NPHS1	O60500-1.1	L1232P	Neutral	0.015
NPHS1	O60500-1.1	L1232Q	Neutral	0.049
NPHS1	O60500-1.1	L1232R	Neutral	0.188
NPHS1	O60500-1.1	L1232S	Neutral	0.094
NPHS1	O60500-1.1	L1232T	Neutral	0.059
NPHS1	O60500-1.1	L1232V	Neutral	0.024
NPHS1	O60500-1.1	L1232W	Neutral	0.013
NPHS1	O60500-1.1	L1232Y	Neutral	0.015
NPHS1	O60500-1.1	P1233A	Neutral	0.072
NPHS1	O60500-1.1	P1233C	Neutral	0.017
NPHS1	O60500-1.1	P1233D	Neutral	0.186
NPHS1	O60500-1.1	P1233E	Neutral	0.223
NPHS1	O60500-1.1	P1233F	Neutral	0.094
NPHS1	O60500-1.1	P1233G	Neutral	0.113
NPHS1	O60500-1.1	P1233H	Neutral	0.07
NPHS1	O60500-1.1	P1233I	Neutral	0.109
NPHS1	O60500-1.1	P1233K	Neutral	0.472
NPHS1	O60500-1.1	P1233L	Neutral	0.095
NPHS1	O60500-1.1	P1233M	Neutral	0.072
NPHS1	O60500-1.1	P1233N	Neutral	0.118
NPHS1	O60500-1.1	P1233Q	Neutral	0.148
NPHS1	O60500-1.1	P1233R	Neutral	0.454
NPHS1	O60500-1.1	P1233S	Neutral	0.1
NPHS1	O60500-1.1	P1233T	Neutral	0.049
NPHS1	O60500-1.1	P1233V	Neutral	0.046
NPHS1	O60500-1.1	P1233W	Neutral	0.287
NPHS1	O60500-1.1	P1233Y	Neutral	0.05
NPHS1	O60500-1.1	F1234A	Pathogenic	0.893
NPHS1	O60500-1.1	F1234C	Pathogenic	0.662
NPHS1	O60500-1.1	F1234D	Pathogenic	0.941
NPHS1	O60500-1.1	F1234E	Pathogenic	0.895
NPHS1	O60500-1.1	F1234G	Pathogenic	0.933
NPHS1	O60500-1.1	F1234H	Pathogenic	0.829
NPHS1	O60500-1.1	F1234I	Neutral	0.353
NPHS1	O60500-1.1	F1234K	Pathogenic	0.886
NPHS1	O60500-1.1	F1234L	Neutral	0.378
NPHS1	O60500-1.1	F1234M	Pathogenic	0.55
NPHS1	O60500-1.1	F1234N	Pathogenic	0.916
NPHS1	O60500-1.1	F1234P	Pathogenic	0.543
NPHS1	O60500-1.1	F1234Q	Pathogenic	0.802
NPHS1	O60500-1.1	F1234R	Pathogenic	0.915
NPHS1	O60500-1.1	F1234S	Pathogenic	0.924
NPHS1	O60500-1.1	F1234T	Pathogenic	0.83
NPHS1	O60500-1.1	F1234V	Pathogenic	0.568
NPHS1	O60500-1.1	F1234W	Pathogenic	0.703
NPHS1	O60500-1.1	F1234Y	Pathogenic	0.844
NPHS1	O60500-1.1	E1235A	Neutral	0.056
NPHS1	O60500-1.1	E1235C	Neutral	0.03
NPHS1	O60500-1.1	E1235D	Neutral	0.032
NPHS1	O60500-1.1	E1235F	Neutral	0.142
NPHS1	O60500-1.1	E1235G	Neutral	0.038
NPHS1	O60500-1.1	E1235H	Neutral	0.03
NPHS1	O60500-1.1	E1235I	Neutral	0.115
NPHS1	O60500-1.1	E1235K	Neutral	0.036
NPHS1	O60500-1.1	E1235L	Neutral	0.101
NPHS1	O60500-1.1	E1235M	Neutral	0.077
NPHS1	O60500-1.1	E1235N	Neutral	0.011
NPHS1	O60500-1.1	E1235P	Neutral	0.06
NPHS1	O60500-1.1	E1235Q	Neutral	0.036
NPHS1	O60500-1.1	E1235R	Neutral	0.034
NPHS1	O60500-1.1	E1235S	Neutral	0.044
NPHS1	O60500-1.1	E1235T	Neutral	0.029
NPHS1	O60500-1.1	E1235V	Neutral	0.059
NPHS1	O60500-1.1	E1235W	Neutral	0.389
NPHS1	O60500-1.1	E1235Y	Neutral	0.077
NPHS1	O60500-1.1	L1236A	Neutral	0.131
NPHS1	O60500-1.1	L1236C	Neutral	0.034
NPHS1	O60500-1.1	L1236D	Neutral	0.113
NPHS1	O60500-1.1	L1236E	Neutral	0.093
NPHS1	O60500-1.1	L1236F	Neutral	0.011
NPHS1	O60500-1.1	L1236G	Neutral	0.101
NPHS1	O60500-1.1	L1236H	Neutral	0.026
NPHS1	O60500-1.1	L1236I	Neutral	0.019
NPHS1	O60500-1.1	L1236K	Neutral	0.19
NPHS1	O60500-1.1	L1236M	Neutral	0.032
NPHS1	O60500-1.1	L1236N	Neutral	0.116
NPHS1	O60500-1.1	L1236P	Neutral	0.021
NPHS1	O60500-1.1	L1236Q	Neutral	0.068
NPHS1	O60500-1.1	L1236R	Neutral	0.246
NPHS1	O60500-1.1	L1236S	Neutral	0.127
NPHS1	O60500-1.1	L1236T	Neutral	0.081
NPHS1	O60500-1.1	L1236V	Neutral	0.034
NPHS1	O60500-1.1	L1236W	Neutral	0.018
NPHS1	O60500-1.1	L1236Y	Neutral	0.022
NPHS1	O60500-1.1	R1237A	Neutral	0.371
NPHS1	O60500-1.1	R1237C	Neutral	0.316
NPHS1	O60500-1.1	R1237D	Neutral	0.043
NPHS1	O60500-1.1	R1237E	Neutral	0.074
NPHS1	O60500-1.1	R1237F	Neutral	0.326
NPHS1	O60500-1.1	R1237G	Neutral	0.282
NPHS1	O60500-1.1	R1237H	Neutral	0.169
NPHS1	O60500-1.1	R1237I	Neutral	0.39
NPHS1	O60500-1.1	R1237K	Neutral	0.054
NPHS1	O60500-1.1	R1237L	Neutral	0.45
NPHS1	O60500-1.1	R1237M	Neutral	0.378
NPHS1	O60500-1.1	R1237N	Neutral	0.103
NPHS1	O60500-1.1	R1237P	Neutral	0.298
NPHS1	O60500-1.1	R1237Q	Neutral	0.165
NPHS1	O60500-1.1	R1237S	Neutral	0.235
NPHS1	O60500-1.1	R1237T	Neutral	0.228
NPHS1	O60500-1.1	R1237V	Neutral	0.295
NPHS1	O60500-1.1	R1237W	Pathogenic	0.502
NPHS1	O60500-1.1	R1237Y	Neutral	0.154
NPHS1	O60500-1.1	G1238A	Neutral	0.122
NPHS1	O60500-1.1	G1238C	Neutral	0.152
NPHS1	O60500-1.1	G1238D	Neutral	0.246
NPHS1	O60500-1.1	G1238E	Neutral	0.216
NPHS1	O60500-1.1	G1238F	Pathogenic	0.654
NPHS1	O60500-1.1	G1238H	Neutral	0.138
NPHS1	O60500-1.1	G1238I	Neutral	0.5
NPHS1	O60500-1.1	G1238K	Neutral	0.462
NPHS1	O60500-1.1	G1238L	Neutral	0.462
NPHS1	O60500-1.1	G1238M	Neutral	0.389
NPHS1	O60500-1.1	G1238N	Neutral	0.299
NPHS1	O60500-1.1	G1238P	Neutral	0.165
NPHS1	O60500-1.1	G1238Q	Neutral	0.143
NPHS1	O60500-1.1	G1238R	Pathogenic	0.544
NPHS1	O60500-1.1	G1238S	Neutral	0.097
NPHS1	O60500-1.1	G1238T	Neutral	0.097
NPHS1	O60500-1.1	G1238V	Neutral	0.284
NPHS1	O60500-1.1	G1238W	Pathogenic	0.916
NPHS1	O60500-1.1	G1238Y	Neutral	0.388
NPHS1	O60500-1.1	H1239A	Neutral	0.02
NPHS1	O60500-1.1	H1239C	Neutral	0.023
NPHS1	O60500-1.1	H1239D	Neutral	0.047
NPHS1	O60500-1.1	H1239E	Neutral	0.038
NPHS1	O60500-1.1	H1239F	Neutral	0.108
NPHS1	O60500-1.1	H1239G	Neutral	0.028
NPHS1	O60500-1.1	H1239I	Neutral	0.041
NPHS1	O60500-1.1	H1239K	Neutral	0.052
NPHS1	O60500-1.1	H1239L	Neutral	0.035
NPHS1	O60500-1.1	H1239M	Neutral	0.026
NPHS1	O60500-1.1	H1239N	Neutral	0.071
NPHS1	O60500-1.1	H1239P	Neutral	0.021
NPHS1	O60500-1.1	H1239Q	Neutral	0.019
NPHS1	O60500-1.1	H1239R	Neutral	0.101
NPHS1	O60500-1.1	H1239S	Neutral	0.025
NPHS1	O60500-1.1	H1239T	Neutral	0.01
NPHS1	O60500-1.1	H1239V	Neutral	0.021
NPHS1	O60500-1.1	H1239W	Neutral	0.238
NPHS1	O60500-1.1	H1239Y	Neutral	0.118
NPHS1	O60500-1.1	L1240A	Neutral	0.415
NPHS1	O60500-1.1	L1240C	Neutral	0.142
NPHS1	O60500-1.1	L1240D	Neutral	0.376
NPHS1	O60500-1.1	L1240E	Neutral	0.326
NPHS1	O60500-1.1	L1240F	Neutral	0.049
NPHS1	O60500-1.1	L1240G	Neutral	0.346
NPHS1	O60500-1.1	L1240H	Neutral	0.11
NPHS1	O60500-1.1	L1240I	Neutral	0.082
NPHS1	O60500-1.1	L1240K	Pathogenic	0.525
NPHS1	O60500-1.1	L1240M	Neutral	0.134
NPHS1	O60500-1.1	L1240N	Neutral	0.383
NPHS1	O60500-1.1	L1240P	Neutral	0.091
NPHS1	O60500-1.1	L1240Q	Neutral	0.256
NPHS1	O60500-1.1	L1240R	Pathogenic	0.606
NPHS1	O60500-1.1	L1240S	Neutral	0.408
NPHS1	O60500-1.1	L1240T	Neutral	0.293
NPHS1	O60500-1.1	L1240V	Neutral	0.142
NPHS1	O60500-1.1	L1240W	Neutral	0.081
NPHS1	O60500-1.1	L1240Y	Neutral	0.094
NPHS1	O60500-1.1	V1241A	Neutral	0.408
NPHS1	O60500-1.1	V1241C	Neutral	0.098
NPHS1	O60500-1.1	V1241D	Neutral	0.37
NPHS1	O60500-1.1	V1241E	Neutral	0.362
NPHS1	O60500-1.1	V1241F	Neutral	0.188
NPHS1	O60500-1.1	V1241G	Neutral	0.34
NPHS1	O60500-1.1	V1241H	Neutral	0.13
NPHS1	O60500-1.1	V1241I	Neutral	0.475
NPHS1	O60500-1.1	V1241K	Pathogenic	0.639
NPHS1	O60500-1.1	V1241L	Neutral	0.259
NPHS1	O60500-1.1	V1241M	Neutral	0.148
NPHS1	O60500-1.1	V1241N	Neutral	0.289
NPHS1	O60500-1.1	V1241P	Neutral	0.089
NPHS1	O60500-1.1	V1241Q	Neutral	0.255
NPHS1	O60500-1.1	V1241R	Pathogenic	0.623
NPHS1	O60500-1.1	V1241S	Neutral	0.31
NPHS1	O60500-1.1	V1241T	Neutral	0.287
NPHS1	O60500-1.1	V1241W	Neutral	0.287
NPHS1	O60500-1.1	V1241Y	Neutral	0.143
LRP5	O75197-1.2	M1A	Neutral	0.229
LRP5	O75197-1.2	M1C	Neutral	0.359
LRP5	O75197-1.2	M1D	Pathogenic	0.522
LRP5	O75197-1.2	M1E	Neutral	0.294
LRP5	O75197-1.2	M1F	Neutral	0.128
LRP5	O75197-1.2	M1G	Pathogenic	0.67
LRP5	O75197-1.2	M1H	Neutral	0.456
LRP5	O75197-1.2	M1I	Neutral	0.046
LRP5	O75197-1.2	M1K	Neutral	0.091
LRP5	O75197-1.2	M1L	Neutral	0.017
LRP5	O75197-1.2	M1N	Neutral	0.296
LRP5	O75197-1.2	M1P	Pathogenic	0.576
LRP5	O75197-1.2	M1Q	Neutral	0.062
LRP5	O75197-1.2	M1R	Neutral	0.088
LRP5	O75197-1.2	M1S	Neutral	0.181
LRP5	O75197-1.2	M1T	Neutral	0.229
LRP5	O75197-1.2	M1V	Neutral	0.072
LRP5	O75197-1.2	M1W	Neutral	0.22
LRP5	O75197-1.2	M1Y	Neutral	0.363
LRP5	O75197-1.2	E2A	Neutral	0.055
LRP5	O75197-1.2	E2C	Neutral	0.479
LRP5	O75197-1.2	E2D	Neutral	0.004
LRP5	O75197-1.2	E2F	Neutral	0.127
LRP5	O75197-1.2	E2G	Neutral	0.183
LRP5	O75197-1.2	E2H	Neutral	0.023
LRP5	O75197-1.2	E2I	Neutral	0.128
LRP5	O75197-1.2	E2K	Neutral	0.011
LRP5	O75197-1.2	E2L	Neutral	0.139
LRP5	O75197-1.2	E2M	Neutral	0.074
LRP5	O75197-1.2	E2N	Neutral	0.043
LRP5	O75197-1.2	E2P	Neutral	0.04
LRP5	O75197-1.2	E2Q	Neutral	0.003
LRP5	O75197-1.2	E2R	Neutral	0.031
LRP5	O75197-1.2	E2S	Neutral	0.025
LRP5	O75197-1.2	E2T	Neutral	0.059
LRP5	O75197-1.2	E2V	Neutral	0.077
LRP5	O75197-1.2	E2W	Neutral	0.085
LRP5	O75197-1.2	E2Y	Neutral	0.091
LRP5	O75197-1.2	A3C	Neutral	0.03
LRP5	O75197-1.2	A3D	Neutral	0.167
LRP5	O75197-1.2	A3E	Neutral	0.067
LRP5	O75197-1.2	A3F	Neutral	0.116
LRP5	O75197-1.2	A3G	Neutral	0.042
LRP5	O75197-1.2	A3H	Neutral	0.301
LRP5	O75197-1.2	A3I	Neutral	0.041
LRP5	O75197-1.2	A3K	Neutral	0.048
LRP5	O75197-1.2	A3L	Neutral	0.045
LRP5	O75197-1.2	A3M	Neutral	0.067
LRP5	O75197-1.2	A3N	Neutral	0.188
LRP5	O75197-1.2	A3P	Neutral	0.107
LRP5	O75197-1.2	A3Q	Neutral	0.094
LRP5	O75197-1.2	A3R	Neutral	0.047
LRP5	O75197-1.2	A3S	Neutral	0.014
LRP5	O75197-1.2	A3T	Neutral	0.051
LRP5	O75197-1.2	A3V	Neutral	0.024
LRP5	O75197-1.2	A3W	Neutral	0.201
LRP5	O75197-1.2	A3Y	Neutral	0.213
LRP5	O75197-1.2	A4C	Neutral	0.022
LRP5	O75197-1.2	A4D	Neutral	0.126
LRP5	O75197-1.2	A4E	Neutral	0.049
LRP5	O75197-1.2	A4F	Neutral	0.085
LRP5	O75197-1.2	A4G	Neutral	0.03
LRP5	O75197-1.2	A4H	Neutral	0.236
LRP5	O75197-1.2	A4I	Neutral	0.03
LRP5	O75197-1.2	A4K	Neutral	0.035
LRP5	O75197-1.2	A4L	Neutral	0.033
LRP5	O75197-1.2	A4M	Neutral	0.049
LRP5	O75197-1.2	A4N	Neutral	0.142
LRP5	O75197-1.2	A4P	Neutral	0.079
LRP5	O75197-1.2	A4Q	Neutral	0.069
LRP5	O75197-1.2	A4R	Neutral	0.034
LRP5	O75197-1.2	A4S	Neutral	0.01
LRP5	O75197-1.2	A4T	Neutral	0.037
LRP5	O75197-1.2	A4V	Neutral	0.017
LRP5	O75197-1.2	A4W	Neutral	0.152
LRP5	O75197-1.2	A4Y	Neutral	0.163
LRP5	O75197-1.2	P5A	Neutral	0.049
LRP5	O75197-1.2	P5C	Neutral	0.36
LRP5	O75197-1.2	P5D	Neutral	0.02
LRP5	O75197-1.2	P5E	Neutral	0.022
LRP5	O75197-1.2	P5F	Neutral	0.438
LRP5	O75197-1.2	P5G	Neutral	0.104
LRP5	O75197-1.2	P5H	Neutral	0.118
LRP5	O75197-1.2	P5I	Neutral	0.205
LRP5	O75197-1.2	P5K	Neutral	0.015
LRP5	O75197-1.2	P5L	Neutral	0.22
LRP5	O75197-1.2	P5M	Neutral	0.124
LRP5	O75197-1.2	P5N	Neutral	0.067
LRP5	O75197-1.2	P5Q	Neutral	0.031
LRP5	O75197-1.2	P5R	Neutral	0.044
LRP5	O75197-1.2	P5S	Neutral	0.037
LRP5	O75197-1.2	P5T	Neutral	0.049
LRP5	O75197-1.2	P5V	Neutral	0.128
LRP5	O75197-1.2	P5W	Neutral	0.33
LRP5	O75197-1.2	P5Y	Neutral	0.347
LRP5	O75197-1.2	P6A	Neutral	0.036
LRP5	O75197-1.2	P6C	Neutral	0.287
LRP5	O75197-1.2	P6D	Neutral	0.014
LRP5	O75197-1.2	P6E	Neutral	0.016
LRP5	O75197-1.2	P6F	Neutral	0.358
LRP5	O75197-1.2	P6G	Neutral	0.077
LRP5	O75197-1.2	P6H	Neutral	0.087
LRP5	O75197-1.2	P6I	Neutral	0.156
LRP5	O75197-1.2	P6K	Neutral	0.011
LRP5	O75197-1.2	P6L	Neutral	0.168
LRP5	O75197-1.2	P6M	Neutral	0.092
LRP5	O75197-1.2	P6N	Neutral	0.049
LRP5	O75197-1.2	P6Q	Neutral	0.023
LRP5	O75197-1.2	P6R	Neutral	0.032
LRP5	O75197-1.2	P6S	Neutral	0.027
LRP5	O75197-1.2	P6T	Neutral	0.035
LRP5	O75197-1.2	P6V	Neutral	0.095
LRP5	O75197-1.2	P6W	Neutral	0.261
LRP5	O75197-1.2	P6Y	Neutral	0.276
LRP5	O75197-1.2	G7A	Neutral	0.005
LRP5	O75197-1.2	G7C	Neutral	0.075
LRP5	O75197-1.2	G7D	Neutral	0.01
LRP5	O75197-1.2	G7E	Neutral	0.034
LRP5	O75197-1.2	G7F	Neutral	0.035
LRP5	O75197-1.2	G7H	Neutral	0.052
LRP5	O75197-1.2	G7I	Neutral	0.101
LRP5	O75197-1.2	G7K	Neutral	0.024
LRP5	O75197-1.2	G7L	Neutral	0.109
LRP5	O75197-1.2	G7M	Neutral	0.058
LRP5	O75197-1.2	G7N	Neutral	0.004
LRP5	O75197-1.2	G7P	Neutral	0.033
LRP5	O75197-1.2	G7Q	Neutral	0.048
LRP5	O75197-1.2	G7R	Neutral	0.023
LRP5	O75197-1.2	G7S	Neutral	0.007
LRP5	O75197-1.2	G7T	Neutral	0.048
LRP5	O75197-1.2	G7V	Neutral	0.06
LRP5	O75197-1.2	G7W	Neutral	0.008
LRP5	O75197-1.2	G7Y	Neutral	0.071
LRP5	O75197-1.2	P8A	Neutral	0.025
LRP5	O75197-1.2	P8C	Neutral	0.221
LRP5	O75197-1.2	P8D	Neutral	0.01
LRP5	O75197-1.2	P8E	Neutral	0.011
LRP5	O75197-1.2	P8F	Neutral	0.282
LRP5	O75197-1.2	P8G	Neutral	0.055
LRP5	O75197-1.2	P8H	Neutral	0.063
LRP5	O75197-1.2	P8I	Neutral	0.115
LRP5	O75197-1.2	P8K	Neutral	0.008
LRP5	O75197-1.2	P8L	Neutral	0.124
LRP5	O75197-1.2	P8M	Neutral	0.066
LRP5	O75197-1.2	P8N	Neutral	0.035
LRP5	O75197-1.2	P8Q	Neutral	0.016
LRP5	O75197-1.2	P8R	Neutral	0.023
LRP5	O75197-1.2	P8S	Neutral	0.019
LRP5	O75197-1.2	P8T	Neutral	0.025
LRP5	O75197-1.2	P8V	Neutral	0.069
LRP5	O75197-1.2	P8W	Neutral	0.199
LRP5	O75197-1.2	P8Y	Neutral	0.211
LRP5	O75197-1.2	P9A	Neutral	0.016
LRP5	O75197-1.2	P9C	Neutral	0.152
LRP5	O75197-1.2	P9D	Neutral	0.006
LRP5	O75197-1.2	P9E	Neutral	0.007
LRP5	O75197-1.2	P9F	Neutral	0.199
LRP5	O75197-1.2	P9G	Neutral	0.036
LRP5	O75197-1.2	P9H	Neutral	0.041
LRP5	O75197-1.2	P9I	Neutral	0.076
LRP5	O75197-1.2	P9K	Neutral	0.005
LRP5	O75197-1.2	P9L	Neutral	0.083
LRP5	O75197-1.2	P9M	Neutral	0.043
LRP5	O75197-1.2	P9N	Neutral	0.022
LRP5	O75197-1.2	P9Q	Neutral	0.01
LRP5	O75197-1.2	P9R	Neutral	0.014
LRP5	O75197-1.2	P9S	Neutral	0.012
LRP5	O75197-1.2	P9T	Neutral	0.016
LRP5	O75197-1.2	P9V	Neutral	0.045
LRP5	O75197-1.2	P9W	Neutral	0.136
LRP5	O75197-1.2	P9Y	Neutral	0.145
LRP5	O75197-1.2	W10A	Neutral	0.022
LRP5	O75197-1.2	W10C	Neutral	0.014
LRP5	O75197-1.2	W10D	Neutral	0.026
LRP5	O75197-1.2	W10E	Neutral	0.01
LRP5	O75197-1.2	W10F	Neutral	0.001
LRP5	O75197-1.2	W10G	Neutral	0.005
LRP5	O75197-1.2	W10H	Neutral	0.007
LRP5	O75197-1.2	W10I	Neutral	0.085
LRP5	O75197-1.2	W10K	Neutral	0.008
LRP5	O75197-1.2	W10L	Neutral	0.027
LRP5	O75197-1.2	W10M	Neutral	0.006
LRP5	O75197-1.2	W10N	Neutral	0.03
LRP5	O75197-1.2	W10P	Neutral	0.092
LRP5	O75197-1.2	W10Q	Neutral	0.005
LRP5	O75197-1.2	W10R	Neutral	0.008
LRP5	O75197-1.2	W10S	Neutral	0.016
LRP5	O75197-1.2	W10T	Neutral	0.007
LRP5	O75197-1.2	W10V	Neutral	0.051
LRP5	O75197-1.2	W10Y	Neutral	0.0
LRP5	O75197-1.2	P11A	Neutral	0.004
LRP5	O75197-1.2	P11C	Neutral	0.043
LRP5	O75197-1.2	P11D	Neutral	0.002
LRP5	O75197-1.2	P11E	Neutral	0.002
LRP5	O75197-1.2	P11F	Neutral	0.058
LRP5	O75197-1.2	P11G	Neutral	0.009
LRP5	O75197-1.2	P11H	Neutral	0.01
LRP5	O75197-1.2	P11I	Neutral	0.02
LRP5	O75197-1.2	P11K	Neutral	0.001
LRP5	O75197-1.2	P11L	Neutral	0.022
LRP5	O75197-1.2	P11M	Neutral	0.011
LRP5	O75197-1.2	P11N	Neutral	0.006
LRP5	O75197-1.2	P11Q	Neutral	0.003
LRP5	O75197-1.2	P11R	Neutral	0.004
LRP5	O75197-1.2	P11S	Neutral	0.003
LRP5	O75197-1.2	P11T	Neutral	0.004
LRP5	O75197-1.2	P11V	Neutral	0.012
LRP5	O75197-1.2	P11W	Neutral	0.038
LRP5	O75197-1.2	P11Y	Neutral	0.04
LRP5	O75197-1.2	L12A	Neutral	0.0
LRP5	O75197-1.2	L12C	Neutral	0.001
LRP5	O75197-1.2	L12D	Neutral	0.003
LRP5	O75197-1.2	L12E	Neutral	0.001
LRP5	O75197-1.2	L12F	Neutral	0.0
LRP5	O75197-1.2	L12G	Neutral	0.006
LRP5	O75197-1.2	L12H	Neutral	0.003
LRP5	O75197-1.2	L12I	Neutral	0.0
LRP5	O75197-1.2	L12K	Neutral	0.0
LRP5	O75197-1.2	L12M	Neutral	0.0
LRP5	O75197-1.2	L12N	Neutral	0.001
LRP5	O75197-1.2	L12P	Neutral	0.004
LRP5	O75197-1.2	L12Q	Neutral	0.001
LRP5	O75197-1.2	L12R	Neutral	0.0
LRP5	O75197-1.2	L12S	Neutral	0.001
LRP5	O75197-1.2	L12T	Neutral	0.0
LRP5	O75197-1.2	L12V	Neutral	0.0
LRP5	O75197-1.2	L12W	Neutral	0.002
LRP5	O75197-1.2	L12Y	Neutral	0.001
LRP5	O75197-1.2	L13A	Neutral	0.001
LRP5	O75197-1.2	L13C	Neutral	0.001
LRP5	O75197-1.2	L13D	Neutral	0.008
LRP5	O75197-1.2	L13E	Neutral	0.003
LRP5	O75197-1.2	L13F	Neutral	0.001
LRP5	O75197-1.2	L13G	Neutral	0.015
LRP5	O75197-1.2	L13H	Neutral	0.006
LRP5	O75197-1.2	L13I	Neutral	0.0
LRP5	O75197-1.2	L13K	Neutral	0.001
LRP5	O75197-1.2	L13M	Neutral	0.0
LRP5	O75197-1.2	L13N	Neutral	0.003
LRP5	O75197-1.2	L13P	Neutral	0.01
LRP5	O75197-1.2	L13Q	Neutral	0.002
LRP5	O75197-1.2	L13R	Neutral	0.001
LRP5	O75197-1.2	L13S	Neutral	0.002
LRP5	O75197-1.2	L13T	Neutral	0.001
LRP5	O75197-1.2	L13V	Neutral	0.0
LRP5	O75197-1.2	L13W	Neutral	0.005
LRP5	O75197-1.2	L13Y	Neutral	0.001
LRP5	O75197-1.2	L14A	Neutral	0.001
LRP5	O75197-1.2	L14C	Neutral	0.001
LRP5	O75197-1.2	L14D	Neutral	0.007
LRP5	O75197-1.2	L14E	Neutral	0.003
LRP5	O75197-1.2	L14F	Neutral	0.001
LRP5	O75197-1.2	L14G	Neutral	0.012
LRP5	O75197-1.2	L14H	Neutral	0.005
LRP5	O75197-1.2	L14I	Neutral	0.0
LRP5	O75197-1.2	L14K	Neutral	0.001
LRP5	O75197-1.2	L14M	Neutral	0.0
LRP5	O75197-1.2	L14N	Neutral	0.003
LRP5	O75197-1.2	L14P	Neutral	0.008
LRP5	O75197-1.2	L14Q	Neutral	0.001
LRP5	O75197-1.2	L14R	Neutral	0.001
LRP5	O75197-1.2	L14S	Neutral	0.001
LRP5	O75197-1.2	L14T	Neutral	0.001
LRP5	O75197-1.2	L14V	Neutral	0.0
LRP5	O75197-1.2	L14W	Neutral	0.004
LRP5	O75197-1.2	L14Y	Neutral	0.001
LRP5	O75197-1.2	L15A	Neutral	0.001
LRP5	O75197-1.2	L15C	Neutral	0.001
LRP5	O75197-1.2	L15D	Neutral	0.006
LRP5	O75197-1.2	L15E	Neutral	0.002
LRP5	O75197-1.2	L15F	Neutral	0.001
LRP5	O75197-1.2	L15G	Neutral	0.011
LRP5	O75197-1.2	L15H	Neutral	0.005
LRP5	O75197-1.2	L15I	Neutral	0.0
LRP5	O75197-1.2	L15K	Neutral	0.001
LRP5	O75197-1.2	L15M	Neutral	0.0
LRP5	O75197-1.2	L15N	Neutral	0.002
LRP5	O75197-1.2	L15P	Neutral	0.008
LRP5	O75197-1.2	L15Q	Neutral	0.001
LRP5	O75197-1.2	L15R	Neutral	0.001
LRP5	O75197-1.2	L15S	Neutral	0.001
LRP5	O75197-1.2	L15T	Neutral	0.001
LRP5	O75197-1.2	L15V	Neutral	0.0
LRP5	O75197-1.2	L15W	Neutral	0.004
LRP5	O75197-1.2	L15Y	Neutral	0.001
LRP5	O75197-1.2	L16A	Neutral	0.004
LRP5	O75197-1.2	L16C	Neutral	0.007
LRP5	O75197-1.2	L16D	Neutral	0.04
LRP5	O75197-1.2	L16E	Neutral	0.016
LRP5	O75197-1.2	L16F	Neutral	0.004
LRP5	O75197-1.2	L16G	Neutral	0.071
LRP5	O75197-1.2	L16H	Neutral	0.031
LRP5	O75197-1.2	L16I	Neutral	0.0
LRP5	O75197-1.2	L16K	Neutral	0.004
LRP5	O75197-1.2	L16M	Neutral	0.0
LRP5	O75197-1.2	L16N	Neutral	0.016
LRP5	O75197-1.2	L16P	Neutral	0.049
LRP5	O75197-1.2	L16Q	Neutral	0.008
LRP5	O75197-1.2	L16R	Neutral	0.004
LRP5	O75197-1.2	L16S	Neutral	0.008
LRP5	O75197-1.2	L16T	Neutral	0.004
LRP5	O75197-1.2	L16V	Neutral	0.001
LRP5	O75197-1.2	L16W	Neutral	0.024
LRP5	O75197-1.2	L16Y	Neutral	0.007
LRP5	O75197-1.2	L17A	Neutral	0.001
LRP5	O75197-1.2	L17C	Neutral	0.002
LRP5	O75197-1.2	L17D	Neutral	0.013
LRP5	O75197-1.2	L17E	Neutral	0.005
LRP5	O75197-1.2	L17F	Neutral	0.001
LRP5	O75197-1.2	L17G	Neutral	0.024
LRP5	O75197-1.2	L17H	Neutral	0.01
LRP5	O75197-1.2	L17I	Neutral	0.0
LRP5	O75197-1.2	L17K	Neutral	0.001
LRP5	O75197-1.2	L17M	Neutral	0.0
LRP5	O75197-1.2	L17N	Neutral	0.005
LRP5	O75197-1.2	L17P	Neutral	0.016
LRP5	O75197-1.2	L17Q	Neutral	0.002
LRP5	O75197-1.2	L17R	Neutral	0.001
LRP5	O75197-1.2	L17S	Neutral	0.003
LRP5	O75197-1.2	L17T	Neutral	0.001
LRP5	O75197-1.2	L17V	Neutral	0.0
LRP5	O75197-1.2	L17W	Neutral	0.008
LRP5	O75197-1.2	L17Y	Neutral	0.002
LRP5	O75197-1.2	L18A	Neutral	0.001
LRP5	O75197-1.2	L18C	Neutral	0.002
LRP5	O75197-1.2	L18D	Neutral	0.012
LRP5	O75197-1.2	L18E	Neutral	0.005
LRP5	O75197-1.2	L18F	Neutral	0.001
LRP5	O75197-1.2	L18G	Neutral	0.023
LRP5	O75197-1.2	L18H	Neutral	0.01
LRP5	O75197-1.2	L18I	Neutral	0.0
LRP5	O75197-1.2	L18K	Neutral	0.001
LRP5	O75197-1.2	L18M	Neutral	0.0
LRP5	O75197-1.2	L18N	Neutral	0.005
LRP5	O75197-1.2	L18P	Neutral	0.015
LRP5	O75197-1.2	L18Q	Neutral	0.002
LRP5	O75197-1.2	L18R	Neutral	0.001
LRP5	O75197-1.2	L18S	Neutral	0.003
LRP5	O75197-1.2	L18T	Neutral	0.001
LRP5	O75197-1.2	L18V	Neutral	0.0
LRP5	O75197-1.2	L18W	Neutral	0.007
LRP5	O75197-1.2	L18Y	Neutral	0.002
LRP5	O75197-1.2	L19A	Neutral	0.002
LRP5	O75197-1.2	L19C	Neutral	0.004
LRP5	O75197-1.2	L19D	Neutral	0.022
LRP5	O75197-1.2	L19E	Neutral	0.009
LRP5	O75197-1.2	L19F	Neutral	0.002
LRP5	O75197-1.2	L19G	Neutral	0.041
LRP5	O75197-1.2	L19H	Neutral	0.017
LRP5	O75197-1.2	L19I	Neutral	0.0
LRP5	O75197-1.2	L19K	Neutral	0.002
LRP5	O75197-1.2	L19M	Neutral	0.0
LRP5	O75197-1.2	L19N	Neutral	0.009
LRP5	O75197-1.2	L19P	Neutral	0.028
LRP5	O75197-1.2	L19Q	Neutral	0.004
LRP5	O75197-1.2	L19R	Neutral	0.002
LRP5	O75197-1.2	L19S	Neutral	0.005
LRP5	O75197-1.2	L19T	Neutral	0.002
LRP5	O75197-1.2	L19V	Neutral	0.001
LRP5	O75197-1.2	L19W	Neutral	0.013
LRP5	O75197-1.2	L19Y	Neutral	0.004
LRP5	O75197-1.2	L20A	Neutral	0.006
LRP5	O75197-1.2	L20C	Neutral	0.011
LRP5	O75197-1.2	L20D	Neutral	0.059
LRP5	O75197-1.2	L20E	Neutral	0.023
LRP5	O75197-1.2	L20F	Neutral	0.006
LRP5	O75197-1.2	L20G	Neutral	0.105
LRP5	O75197-1.2	L20H	Neutral	0.046
LRP5	O75197-1.2	L20I	Neutral	0.001
LRP5	O75197-1.2	L20K	Neutral	0.006
LRP5	O75197-1.2	L20M	Neutral	0.001
LRP5	O75197-1.2	L20N	Neutral	0.024
LRP5	O75197-1.2	L20P	Neutral	0.073
LRP5	O75197-1.2	L20Q	Neutral	0.011
LRP5	O75197-1.2	L20R	Neutral	0.006
LRP5	O75197-1.2	L20S	Neutral	0.013
LRP5	O75197-1.2	L20T	Neutral	0.006
LRP5	O75197-1.2	L20V	Neutral	0.001
LRP5	O75197-1.2	L20W	Neutral	0.036
LRP5	O75197-1.2	L20Y	Neutral	0.011
LRP5	O75197-1.2	A21C	Neutral	0.001
LRP5	O75197-1.2	A21D	Neutral	0.005
LRP5	O75197-1.2	A21E	Neutral	0.002
LRP5	O75197-1.2	A21F	Neutral	0.003
LRP5	O75197-1.2	A21G	Neutral	0.001
LRP5	O75197-1.2	A21H	Neutral	0.011
LRP5	O75197-1.2	A21I	Neutral	0.001
LRP5	O75197-1.2	A21K	Neutral	0.001
LRP5	O75197-1.2	A21L	Neutral	0.001
LRP5	O75197-1.2	A21M	Neutral	0.002
LRP5	O75197-1.2	A21N	Neutral	0.006
LRP5	O75197-1.2	A21P	Neutral	0.003
LRP5	O75197-1.2	A21Q	Neutral	0.003
LRP5	O75197-1.2	A21R	Neutral	0.001
LRP5	O75197-1.2	A21S	Neutral	0.0
LRP5	O75197-1.2	A21T	Neutral	0.001
LRP5	O75197-1.2	A21V	Neutral	0.001
LRP5	O75197-1.2	A21W	Neutral	0.006
LRP5	O75197-1.2	A21Y	Neutral	0.007
LRP5	O75197-1.2	L22A	Neutral	0.0
LRP5	O75197-1.2	L22C	Neutral	0.001
LRP5	O75197-1.2	L22D	Neutral	0.005
LRP5	O75197-1.2	L22E	Neutral	0.002
LRP5	O75197-1.2	L22F	Neutral	0.001
LRP5	O75197-1.2	L22G	Neutral	0.009
LRP5	O75197-1.2	L22H	Neutral	0.004
LRP5	O75197-1.2	L22I	Neutral	0.0
LRP5	O75197-1.2	L22K	Neutral	0.0
LRP5	O75197-1.2	L22M	Neutral	0.0
LRP5	O75197-1.2	L22N	Neutral	0.002
LRP5	O75197-1.2	L22P	Neutral	0.006
LRP5	O75197-1.2	L22Q	Neutral	0.001
LRP5	O75197-1.2	L22R	Neutral	0.0
LRP5	O75197-1.2	L22S	Neutral	0.001
LRP5	O75197-1.2	L22T	Neutral	0.0
LRP5	O75197-1.2	L22V	Neutral	0.0
LRP5	O75197-1.2	L22W	Neutral	0.003
LRP5	O75197-1.2	L22Y	Neutral	0.001
LRP5	O75197-1.2	C23A	Neutral	0.003
LRP5	O75197-1.2	C23D	Neutral	0.036
LRP5	O75197-1.2	C23E	Neutral	0.11
LRP5	O75197-1.2	C23F	Neutral	0.026
LRP5	O75197-1.2	C23G	Neutral	0.066
LRP5	O75197-1.2	C23H	Neutral	0.074
LRP5	O75197-1.2	C23I	Neutral	0.009
LRP5	O75197-1.2	C23K	Neutral	0.028
LRP5	O75197-1.2	C23L	Neutral	0.01
LRP5	O75197-1.2	C23M	Neutral	0.014
LRP5	O75197-1.2	C23N	Neutral	0.041
LRP5	O75197-1.2	C23P	Neutral	0.124
LRP5	O75197-1.2	C23Q	Neutral	0.056
LRP5	O75197-1.2	C23R	Neutral	0.027
LRP5	O75197-1.2	C23S	Neutral	0.008
LRP5	O75197-1.2	C23T	Neutral	0.01
LRP5	O75197-1.2	C23V	Neutral	0.015
LRP5	O75197-1.2	C23W	Neutral	0.017
LRP5	O75197-1.2	C23Y	Neutral	0.051
LRP5	O75197-1.2	G24A	Neutral	0.0
LRP5	O75197-1.2	G24C	Neutral	0.004
LRP5	O75197-1.2	G24D	Neutral	0.0
LRP5	O75197-1.2	G24E	Neutral	0.002
LRP5	O75197-1.2	G24F	Neutral	0.002
LRP5	O75197-1.2	G24H	Neutral	0.002
LRP5	O75197-1.2	G24I	Neutral	0.005
LRP5	O75197-1.2	G24K	Neutral	0.001
LRP5	O75197-1.2	G24L	Neutral	0.005
LRP5	O75197-1.2	G24M	Neutral	0.003
LRP5	O75197-1.2	G24N	Neutral	0.0
LRP5	O75197-1.2	G24P	Neutral	0.001
LRP5	O75197-1.2	G24Q	Neutral	0.002
LRP5	O75197-1.2	G24R	Neutral	0.001
LRP5	O75197-1.2	G24S	Neutral	0.0
LRP5	O75197-1.2	G24T	Neutral	0.002
LRP5	O75197-1.2	G24V	Neutral	0.003
LRP5	O75197-1.2	G24W	Neutral	0.0
LRP5	O75197-1.2	G24Y	Neutral	0.003
LRP5	O75197-1.2	C25A	Neutral	0.006
LRP5	O75197-1.2	C25D	Neutral	0.062
LRP5	O75197-1.2	C25E	Neutral	0.18
LRP5	O75197-1.2	C25F	Neutral	0.045
LRP5	O75197-1.2	C25G	Neutral	0.111
LRP5	O75197-1.2	C25H	Neutral	0.124
LRP5	O75197-1.2	C25I	Neutral	0.015
LRP5	O75197-1.2	C25K	Neutral	0.048
LRP5	O75197-1.2	C25L	Neutral	0.017
LRP5	O75197-1.2	C25M	Neutral	0.025
LRP5	O75197-1.2	C25N	Neutral	0.071
LRP5	O75197-1.2	C25P	Neutral	0.2
LRP5	O75197-1.2	C25Q	Neutral	0.094
LRP5	O75197-1.2	C25R	Neutral	0.046
LRP5	O75197-1.2	C25S	Neutral	0.013
LRP5	O75197-1.2	C25T	Neutral	0.017
LRP5	O75197-1.2	C25V	Neutral	0.026
LRP5	O75197-1.2	C25W	Neutral	0.029
LRP5	O75197-1.2	C25Y	Neutral	0.086
LRP5	O75197-1.2	P26A	Neutral	0.05
LRP5	O75197-1.2	P26C	Neutral	0.364
LRP5	O75197-1.2	P26D	Neutral	0.02
LRP5	O75197-1.2	P26E	Neutral	0.022
LRP5	O75197-1.2	P26F	Neutral	0.442
LRP5	O75197-1.2	P26G	Neutral	0.105
LRP5	O75197-1.2	P26H	Neutral	0.119
LRP5	O75197-1.2	P26I	Neutral	0.207
LRP5	O75197-1.2	P26K	Neutral	0.016
LRP5	O75197-1.2	P26L	Neutral	0.223
LRP5	O75197-1.2	P26M	Neutral	0.125
LRP5	O75197-1.2	P26N	Neutral	0.068
LRP5	O75197-1.2	P26Q	Neutral	0.032
LRP5	O75197-1.2	P26R	Neutral	0.045
LRP5	O75197-1.2	P26S	Neutral	0.038
LRP5	O75197-1.2	P26T	Neutral	0.049
LRP5	O75197-1.2	P26V	Neutral	0.13
LRP5	O75197-1.2	P26W	Neutral	0.334
LRP5	O75197-1.2	P26Y	Neutral	0.351
LRP5	O75197-1.2	A27C	Neutral	0.002
LRP5	O75197-1.2	A27D	Neutral	0.013
LRP5	O75197-1.2	A27E	Neutral	0.005
LRP5	O75197-1.2	A27F	Neutral	0.008
LRP5	O75197-1.2	A27G	Neutral	0.003
LRP5	O75197-1.2	A27H	Neutral	0.027
LRP5	O75197-1.2	A27I	Neutral	0.003
LRP5	O75197-1.2	A27K	Neutral	0.003
LRP5	O75197-1.2	A27L	Neutral	0.003
LRP5	O75197-1.2	A27M	Neutral	0.005
LRP5	O75197-1.2	A27N	Neutral	0.015
LRP5	O75197-1.2	A27P	Neutral	0.008
LRP5	O75197-1.2	A27Q	Neutral	0.007
LRP5	O75197-1.2	A27R	Neutral	0.003
LRP5	O75197-1.2	A27S	Neutral	0.001
LRP5	O75197-1.2	A27T	Neutral	0.003
LRP5	O75197-1.2	A27V	Neutral	0.002
LRP5	O75197-1.2	A27W	Neutral	0.016
LRP5	O75197-1.2	A27Y	Neutral	0.017
LRP5	O75197-1.2	P28A	Neutral	0.01
LRP5	O75197-1.2	P28C	Neutral	0.096
LRP5	O75197-1.2	P28D	Neutral	0.004
LRP5	O75197-1.2	P28E	Neutral	0.004
LRP5	O75197-1.2	P28F	Neutral	0.128
LRP5	O75197-1.2	P28G	Neutral	0.021
LRP5	O75197-1.2	P28H	Neutral	0.025
LRP5	O75197-1.2	P28I	Neutral	0.046
LRP5	O75197-1.2	P28K	Neutral	0.003
LRP5	O75197-1.2	P28L	Neutral	0.05
LRP5	O75197-1.2	P28M	Neutral	0.026
LRP5	O75197-1.2	P28N	Neutral	0.013
LRP5	O75197-1.2	P28Q	Neutral	0.006
LRP5	O75197-1.2	P28R	Neutral	0.009
LRP5	O75197-1.2	P28S	Neutral	0.007
LRP5	O75197-1.2	P28T	Neutral	0.01
LRP5	O75197-1.2	P28V	Neutral	0.027
LRP5	O75197-1.2	P28W	Neutral	0.085
LRP5	O75197-1.2	P28Y	Neutral	0.091
LRP5	O75197-1.2	A29C	Neutral	0.001
LRP5	O75197-1.2	A29D	Neutral	0.003
LRP5	O75197-1.2	A29E	Neutral	0.001
LRP5	O75197-1.2	A29F	Neutral	0.002
LRP5	O75197-1.2	A29G	Neutral	0.001
LRP5	O75197-1.2	A29H	Neutral	0.007
LRP5	O75197-1.2	A29I	Neutral	0.001
LRP5	O75197-1.2	A29K	Neutral	0.001
LRP5	O75197-1.2	A29L	Neutral	0.001
LRP5	O75197-1.2	A29M	Neutral	0.001
LRP5	O75197-1.2	A29N	Neutral	0.004
LRP5	O75197-1.2	A29P	Neutral	0.002
LRP5	O75197-1.2	A29Q	Neutral	0.002
LRP5	O75197-1.2	A29R	Neutral	0.001
LRP5	O75197-1.2	A29S	Neutral	0.0
LRP5	O75197-1.2	A29T	Neutral	0.001
LRP5	O75197-1.2	A29V	Neutral	0.0
LRP5	O75197-1.2	A29W	Neutral	0.004
LRP5	O75197-1.2	A29Y	Neutral	0.005
LRP5	O75197-1.2	A30C	Neutral	0.0
LRP5	O75197-1.2	A30D	Neutral	0.002
LRP5	O75197-1.2	A30E	Neutral	0.001
LRP5	O75197-1.2	A30F	Neutral	0.001
LRP5	O75197-1.2	A30G	Neutral	0.0
LRP5	O75197-1.2	A30H	Neutral	0.003
LRP5	O75197-1.2	A30I	Neutral	0.0
LRP5	O75197-1.2	A30K	Neutral	0.0
LRP5	O75197-1.2	A30L	Neutral	0.0
LRP5	O75197-1.2	A30M	Neutral	0.001
LRP5	O75197-1.2	A30N	Neutral	0.002
LRP5	O75197-1.2	A30P	Neutral	0.001
LRP5	O75197-1.2	A30Q	Neutral	0.001
LRP5	O75197-1.2	A30R	Neutral	0.0
LRP5	O75197-1.2	A30S	Neutral	0.0
LRP5	O75197-1.2	A30T	Neutral	0.0
LRP5	O75197-1.2	A30V	Neutral	0.0
LRP5	O75197-1.2	A30W	Neutral	0.002
LRP5	O75197-1.2	A30Y	Neutral	0.002
LRP5	O75197-1.2	A31C	Neutral	0.062
LRP5	O75197-1.2	A31D	Neutral	0.297
LRP5	O75197-1.2	A31E	Neutral	0.132
LRP5	O75197-1.2	A31F	Neutral	0.215
LRP5	O75197-1.2	A31G	Neutral	0.084
LRP5	O75197-1.2	A31H	Neutral	0.475
LRP5	O75197-1.2	A31I	Neutral	0.083
LRP5	O75197-1.2	A31K	Neutral	0.096
LRP5	O75197-1.2	A31L	Neutral	0.09
LRP5	O75197-1.2	A31M	Neutral	0.131
LRP5	O75197-1.2	A31N	Neutral	0.328
LRP5	O75197-1.2	A31P	Neutral	0.202
LRP5	O75197-1.2	A31Q	Neutral	0.18
LRP5	O75197-1.2	A31R	Neutral	0.093
LRP5	O75197-1.2	A31S	Neutral	0.029
LRP5	O75197-1.2	A31T	Neutral	0.102
LRP5	O75197-1.2	A31V	Neutral	0.049
LRP5	O75197-1.2	A31W	Neutral	0.346
LRP5	O75197-1.2	A31Y	Neutral	0.363
LRP5	O75197-1.2	S32A	Neutral	0.009
LRP5	O75197-1.2	S32C	Neutral	0.045
LRP5	O75197-1.2	S32D	Neutral	0.019
LRP5	O75197-1.2	S32E	Neutral	0.021
LRP5	O75197-1.2	S32F	Neutral	0.061
LRP5	O75197-1.2	S32G	Neutral	0.035
LRP5	O75197-1.2	S32H	Neutral	0.088
LRP5	O75197-1.2	S32I	Neutral	0.061
LRP5	O75197-1.2	S32K	Neutral	0.015
LRP5	O75197-1.2	S32L	Neutral	0.066
LRP5	O75197-1.2	S32M	Neutral	0.034
LRP5	O75197-1.2	S32N	Neutral	0.007
LRP5	O75197-1.2	S32P	Neutral	0.056
LRP5	O75197-1.2	S32Q	Neutral	0.03
LRP5	O75197-1.2	S32R	Neutral	0.043
LRP5	O75197-1.2	S32T	Neutral	0.01
LRP5	O75197-1.2	S32V	Neutral	0.101
LRP5	O75197-1.2	S32W	Neutral	0.11
LRP5	O75197-1.2	S32Y	Neutral	0.118
LRP5	O75197-1.2	P33A	Pathogenic	0.846
LRP5	O75197-1.2	P33C	Pathogenic	0.984
LRP5	O75197-1.2	P33D	Pathogenic	0.685
LRP5	O75197-1.2	P33E	Pathogenic	0.704
LRP5	O75197-1.2	P33F	Pathogenic	0.988
LRP5	O75197-1.2	P33G	Pathogenic	0.925
LRP5	O75197-1.2	P33H	Pathogenic	0.934
LRP5	O75197-1.2	P33I	Pathogenic	0.965
LRP5	O75197-1.2	P33K	Pathogenic	0.625
LRP5	O75197-1.2	P33L	Pathogenic	0.968
LRP5	O75197-1.2	P33M	Pathogenic	0.937
LRP5	O75197-1.2	P33N	Pathogenic	0.884
LRP5	O75197-1.2	P33Q	Pathogenic	0.774
LRP5	O75197-1.2	P33R	Pathogenic	0.83
LRP5	O75197-1.2	P33S	Pathogenic	0.803
LRP5	O75197-1.2	P33T	Pathogenic	0.844
LRP5	O75197-1.2	P33V	Pathogenic	0.94
LRP5	O75197-1.2	P33W	Pathogenic	0.981
LRP5	O75197-1.2	P33Y	Pathogenic	0.983
LRP5	O75197-1.2	L34A	Neutral	0.143
LRP5	O75197-1.2	L34C	Neutral	0.239
LRP5	O75197-1.2	L34D	Pathogenic	0.651
LRP5	O75197-1.2	L34E	Neutral	0.415
LRP5	O75197-1.2	L34F	Neutral	0.16
LRP5	O75197-1.2	L34G	Pathogenic	0.776
LRP5	O75197-1.2	L34H	Pathogenic	0.589
LRP5	O75197-1.2	L34I	Neutral	0.02
LRP5	O75197-1.2	L34K	Neutral	0.146
LRP5	O75197-1.2	L34M	Neutral	0.015
LRP5	O75197-1.2	L34N	Neutral	0.418
LRP5	O75197-1.2	L34P	Pathogenic	0.698
LRP5	O75197-1.2	L34Q	Neutral	0.255
LRP5	O75197-1.2	L34R	Neutral	0.142
LRP5	O75197-1.2	L34S	Neutral	0.274
LRP5	O75197-1.2	L34T	Neutral	0.143
LRP5	O75197-1.2	L34V	Neutral	0.041
LRP5	O75197-1.2	L34W	Pathogenic	0.527
LRP5	O75197-1.2	L34Y	Neutral	0.242
LRP5	O75197-1.2	L35A	Pathogenic	0.71
LRP5	O75197-1.2	L35C	Pathogenic	0.822
LRP5	O75197-1.2	L35D	Pathogenic	0.965
LRP5	O75197-1.2	L35E	Pathogenic	0.912
LRP5	O75197-1.2	L35F	Pathogenic	0.735
LRP5	O75197-1.2	L35G	Pathogenic	0.981
LRP5	O75197-1.2	L35H	Pathogenic	0.955
LRP5	O75197-1.2	L35I	Neutral	0.232
LRP5	O75197-1.2	L35K	Pathogenic	0.715
LRP5	O75197-1.2	L35M	Neutral	0.179
LRP5	O75197-1.2	L35N	Pathogenic	0.913
LRP5	O75197-1.2	L35P	Pathogenic	0.971
LRP5	O75197-1.2	L35Q	Pathogenic	0.833
LRP5	O75197-1.2	L35R	Pathogenic	0.708
LRP5	O75197-1.2	L35S	Pathogenic	0.847
LRP5	O75197-1.2	L35T	Pathogenic	0.709
LRP5	O75197-1.2	L35V	Neutral	0.388
LRP5	O75197-1.2	L35W	Pathogenic	0.942
LRP5	O75197-1.2	L35Y	Pathogenic	0.824
LRP5	O75197-1.2	L36A	Pathogenic	0.659
LRP5	O75197-1.2	L36C	Pathogenic	0.785
LRP5	O75197-1.2	L36D	Pathogenic	0.956
LRP5	O75197-1.2	L36E	Pathogenic	0.892
LRP5	O75197-1.2	L36F	Pathogenic	0.688
LRP5	O75197-1.2	L36G	Pathogenic	0.976
LRP5	O75197-1.2	L36H	Pathogenic	0.943
LRP5	O75197-1.2	L36I	Neutral	0.193
LRP5	O75197-1.2	L36K	Pathogenic	0.665
LRP5	O75197-1.2	L36M	Neutral	0.147
LRP5	O75197-1.2	L36N	Pathogenic	0.893
LRP5	O75197-1.2	L36P	Pathogenic	0.964
LRP5	O75197-1.2	L36Q	Pathogenic	0.798
LRP5	O75197-1.2	L36R	Pathogenic	0.658
LRP5	O75197-1.2	L36S	Pathogenic	0.814
LRP5	O75197-1.2	L36T	Pathogenic	0.659
LRP5	O75197-1.2	L36V	Neutral	0.334
LRP5	O75197-1.2	L36W	Pathogenic	0.928
LRP5	O75197-1.2	L36Y	Pathogenic	0.787
LRP5	O75197-1.2	F37A	Pathogenic	0.684
LRP5	O75197-1.2	F37C	Pathogenic	0.803
LRP5	O75197-1.2	F37D	Pathogenic	0.723
LRP5	O75197-1.2	F37E	Pathogenic	0.752
LRP5	O75197-1.2	F37G	Pathogenic	0.829
LRP5	O75197-1.2	F37H	Neutral	0.398
LRP5	O75197-1.2	F37I	Neutral	0.488
LRP5	O75197-1.2	F37K	Pathogenic	0.697
LRP5	O75197-1.2	F37L	Neutral	0.471
LRP5	O75197-1.2	F37M	Neutral	0.369
LRP5	O75197-1.2	F37N	Pathogenic	0.754
LRP5	O75197-1.2	F37P	Pathogenic	0.968
LRP5	O75197-1.2	F37Q	Pathogenic	0.816
LRP5	O75197-1.2	F37R	Pathogenic	0.69
LRP5	O75197-1.2	F37S	Pathogenic	0.616
LRP5	O75197-1.2	F37T	Pathogenic	0.683
LRP5	O75197-1.2	F37V	Pathogenic	0.63
LRP5	O75197-1.2	F37W	Neutral	0.169
LRP5	O75197-1.2	F37Y	Neutral	0.016
LRP5	O75197-1.2	A38C	Pathogenic	0.535
LRP5	O75197-1.2	A38D	Pathogenic	0.88
LRP5	O75197-1.2	A38E	Pathogenic	0.725
LRP5	O75197-1.2	A38F	Pathogenic	0.827
LRP5	O75197-1.2	A38G	Pathogenic	0.615
LRP5	O75197-1.2	A38H	Pathogenic	0.94
LRP5	O75197-1.2	A38I	Pathogenic	0.612
LRP5	O75197-1.2	A38K	Pathogenic	0.649
LRP5	O75197-1.2	A38L	Pathogenic	0.634
LRP5	O75197-1.2	A38M	Pathogenic	0.725
LRP5	O75197-1.2	A38N	Pathogenic	0.895
LRP5	O75197-1.2	A38P	Pathogenic	0.815
LRP5	O75197-1.2	A38Q	Pathogenic	0.792
LRP5	O75197-1.2	A38R	Pathogenic	0.641
LRP5	O75197-1.2	A38S	Neutral	0.341
LRP5	O75197-1.2	A38T	Pathogenic	0.665
LRP5	O75197-1.2	A38V	Neutral	0.475
LRP5	O75197-1.2	A38W	Pathogenic	0.902
LRP5	O75197-1.2	A38Y	Pathogenic	0.908
LRP5	O75197-1.2	N39A	Pathogenic	0.905
LRP5	O75197-1.2	N39C	Pathogenic	0.943
LRP5	O75197-1.2	N39D	Neutral	0.406
LRP5	O75197-1.2	N39E	Pathogenic	0.698
LRP5	O75197-1.2	N39F	Pathogenic	0.884
LRP5	O75197-1.2	N39G	Pathogenic	0.569
LRP5	O75197-1.2	N39H	Neutral	0.287
LRP5	O75197-1.2	N39I	Pathogenic	0.884
LRP5	O75197-1.2	N39K	Pathogenic	0.618
LRP5	O75197-1.2	N39L	Pathogenic	0.893
LRP5	O75197-1.2	N39M	Pathogenic	0.807
LRP5	O75197-1.2	N39P	Pathogenic	0.873
LRP5	O75197-1.2	N39Q	Pathogenic	0.628
LRP5	O75197-1.2	N39R	Pathogenic	0.61
LRP5	O75197-1.2	N39S	Neutral	0.318
LRP5	O75197-1.2	N39T	Pathogenic	0.53
LRP5	O75197-1.2	N39V	Pathogenic	0.93
LRP5	O75197-1.2	N39W	Pathogenic	0.936
LRP5	O75197-1.2	N39Y	Pathogenic	0.839
LRP5	O75197-1.2	R40A	Neutral	0.474
LRP5	O75197-1.2	R40C	Pathogenic	0.824
LRP5	O75197-1.2	R40D	Pathogenic	0.882
LRP5	O75197-1.2	R40E	Neutral	0.424
LRP5	O75197-1.2	R40F	Pathogenic	0.712
LRP5	O75197-1.2	R40G	Pathogenic	0.778
LRP5	O75197-1.2	R40H	Neutral	0.273
LRP5	O75197-1.2	R40I	Pathogenic	0.706
LRP5	O75197-1.2	R40K	Neutral	0.102
LRP5	O75197-1.2	R40L	Neutral	0.463
LRP5	O75197-1.2	R40M	Neutral	0.302
LRP5	O75197-1.2	R40N	Neutral	0.411
LRP5	O75197-1.2	R40P	Pathogenic	0.663
LRP5	O75197-1.2	R40Q	Neutral	0.144
LRP5	O75197-1.2	R40S	Pathogenic	0.553
LRP5	O75197-1.2	R40T	Neutral	0.496
LRP5	O75197-1.2	R40V	Pathogenic	0.797
LRP5	O75197-1.2	R40W	Pathogenic	0.62
LRP5	O75197-1.2	R40Y	Pathogenic	0.632
LRP5	O75197-1.2	R41A	Neutral	0.275
LRP5	O75197-1.2	R41C	Pathogenic	0.665
LRP5	O75197-1.2	R41D	Pathogenic	0.759
LRP5	O75197-1.2	R41E	Neutral	0.237
LRP5	O75197-1.2	R41F	Pathogenic	0.511
LRP5	O75197-1.2	R41G	Pathogenic	0.596
LRP5	O75197-1.2	R41H	Neutral	0.137
LRP5	O75197-1.2	R41I	Pathogenic	0.503
LRP5	O75197-1.2	R41K	Neutral	0.046
LRP5	O75197-1.2	R41L	Neutral	0.267
LRP5	O75197-1.2	R41M	Neutral	0.154
LRP5	O75197-1.2	R41N	Neutral	0.228
LRP5	O75197-1.2	R41P	Neutral	0.454
LRP5	O75197-1.2	R41Q	Neutral	0.066
LRP5	O75197-1.2	R41S	Neutral	0.343
LRP5	O75197-1.2	R41T	Neutral	0.293
LRP5	O75197-1.2	R41V	Pathogenic	0.624
LRP5	O75197-1.2	R41W	Neutral	0.408
LRP5	O75197-1.2	R41Y	Neutral	0.421
LRP5	O75197-1.2	D42A	Pathogenic	0.916
LRP5	O75197-1.2	D42C	Pathogenic	0.949
LRP5	O75197-1.2	D42E	Neutral	0.23
LRP5	O75197-1.2	D42F	Pathogenic	0.895
LRP5	O75197-1.2	D42G	Pathogenic	0.82
LRP5	O75197-1.2	D42H	Pathogenic	0.806
LRP5	O75197-1.2	D42I	Pathogenic	0.895
LRP5	O75197-1.2	D42K	Pathogenic	0.882
LRP5	O75197-1.2	D42L	Pathogenic	0.966
LRP5	O75197-1.2	D42M	Pathogenic	0.934
LRP5	O75197-1.2	D42N	Neutral	0.473
LRP5	O75197-1.2	D42P	Pathogenic	0.719
LRP5	O75197-1.2	D42Q	Pathogenic	0.653
LRP5	O75197-1.2	D42R	Pathogenic	0.956
LRP5	O75197-1.2	D42S	Pathogenic	0.617
LRP5	O75197-1.2	D42T	Pathogenic	0.795
LRP5	O75197-1.2	D42V	Pathogenic	0.937
LRP5	O75197-1.2	D42W	Pathogenic	0.942
LRP5	O75197-1.2	D42Y	Pathogenic	0.946
LRP5	O75197-1.2	V43A	Neutral	0.047
LRP5	O75197-1.2	V43C	Neutral	0.22
LRP5	O75197-1.2	V43D	Neutral	0.355
LRP5	O75197-1.2	V43E	Neutral	0.171
LRP5	O75197-1.2	V43F	Neutral	0.17
LRP5	O75197-1.2	V43G	Pathogenic	0.505
LRP5	O75197-1.2	V43H	Pathogenic	0.552
LRP5	O75197-1.2	V43I	Neutral	0.002
LRP5	O75197-1.2	V43K	Neutral	0.126
LRP5	O75197-1.2	V43L	Neutral	0.024
LRP5	O75197-1.2	V43M	Neutral	0.036
LRP5	O75197-1.2	V43N	Neutral	0.392
LRP5	O75197-1.2	V43P	Neutral	0.406
LRP5	O75197-1.2	V43Q	Neutral	0.229
LRP5	O75197-1.2	V43R	Neutral	0.298
LRP5	O75197-1.2	V43S	Neutral	0.253
LRP5	O75197-1.2	V43T	Neutral	0.047
LRP5	O75197-1.2	V43W	Pathogenic	0.546
LRP5	O75197-1.2	V43Y	Neutral	0.212
LRP5	O75197-1.2	R44A	Pathogenic	0.748
LRP5	O75197-1.2	R44C	Pathogenic	0.939
LRP5	O75197-1.2	R44D	Pathogenic	0.961
LRP5	O75197-1.2	R44E	Pathogenic	0.709
LRP5	O75197-1.2	R44F	Pathogenic	0.891
LRP5	O75197-1.2	R44G	Pathogenic	0.92
LRP5	O75197-1.2	R44H	Pathogenic	0.554
LRP5	O75197-1.2	R44I	Pathogenic	0.888
LRP5	O75197-1.2	R44K	Neutral	0.273
LRP5	O75197-1.2	R44L	Pathogenic	0.74
LRP5	O75197-1.2	R44M	Pathogenic	0.588
LRP5	O75197-1.2	R44N	Pathogenic	0.697
LRP5	O75197-1.2	R44P	Pathogenic	0.867
LRP5	O75197-1.2	R44Q	Neutral	0.357
LRP5	O75197-1.2	R44S	Pathogenic	0.803
LRP5	O75197-1.2	R44T	Pathogenic	0.764
LRP5	O75197-1.2	R44V	Pathogenic	0.928
LRP5	O75197-1.2	R44W	Pathogenic	0.843
LRP5	O75197-1.2	R44Y	Pathogenic	0.85
LRP5	O75197-1.2	L45A	Neutral	0.198
LRP5	O75197-1.2	L45C	Neutral	0.318
LRP5	O75197-1.2	L45D	Pathogenic	0.734
LRP5	O75197-1.2	L45E	Pathogenic	0.512
LRP5	O75197-1.2	L45F	Neutral	0.219
LRP5	O75197-1.2	L45G	Pathogenic	0.837
LRP5	O75197-1.2	L45H	Pathogenic	0.679
LRP5	O75197-1.2	L45I	Neutral	0.03
LRP5	O75197-1.2	L45K	Neutral	0.202
LRP5	O75197-1.2	L45M	Neutral	0.021
LRP5	O75197-1.2	L45N	Pathogenic	0.515
LRP5	O75197-1.2	L45P	Pathogenic	0.774
LRP5	O75197-1.2	L45Q	Neutral	0.336
LRP5	O75197-1.2	L45R	Neutral	0.197
LRP5	O75197-1.2	L45S	Neutral	0.358
LRP5	O75197-1.2	L45T	Neutral	0.197
LRP5	O75197-1.2	L45V	Neutral	0.06
LRP5	O75197-1.2	L45W	Pathogenic	0.622
LRP5	O75197-1.2	L45Y	Neutral	0.321
LRP5	O75197-1.2	V46A	Neutral	0.157
LRP5	O75197-1.2	V46C	Pathogenic	0.516
LRP5	O75197-1.2	V46D	Pathogenic	0.675
LRP5	O75197-1.2	V46E	Neutral	0.438
LRP5	O75197-1.2	V46F	Neutral	0.436
LRP5	O75197-1.2	V46G	Pathogenic	0.794
LRP5	O75197-1.2	V46H	Pathogenic	0.823
LRP5	O75197-1.2	V46I	Neutral	0.009
LRP5	O75197-1.2	V46K	Neutral	0.353
LRP5	O75197-1.2	V46L	Neutral	0.084
LRP5	O75197-1.2	V46M	Neutral	0.123
LRP5	O75197-1.2	V46N	Pathogenic	0.708
LRP5	O75197-1.2	V46P	Pathogenic	0.72
LRP5	O75197-1.2	V46Q	Pathogenic	0.529
LRP5	O75197-1.2	V46R	Pathogenic	0.616
LRP5	O75197-1.2	V46S	Pathogenic	0.561
LRP5	O75197-1.2	V46T	Neutral	0.156
LRP5	O75197-1.2	V46W	Pathogenic	0.819
LRP5	O75197-1.2	V46Y	Pathogenic	0.504
LRP5	O75197-1.2	D47A	Pathogenic	0.685
LRP5	O75197-1.2	D47C	Pathogenic	0.789
LRP5	O75197-1.2	D47E	Neutral	0.056
LRP5	O75197-1.2	D47F	Pathogenic	0.63
LRP5	O75197-1.2	D47G	Neutral	0.477
LRP5	O75197-1.2	D47H	Neutral	0.454
LRP5	O75197-1.2	D47I	Pathogenic	0.631
LRP5	O75197-1.2	D47K	Pathogenic	0.599
LRP5	O75197-1.2	D47L	Pathogenic	0.851
LRP5	O75197-1.2	D47M	Pathogenic	0.741
LRP5	O75197-1.2	D47N	Neutral	0.152
LRP5	O75197-1.2	D47P	Neutral	0.339
LRP5	O75197-1.2	D47Q	Neutral	0.274
LRP5	O75197-1.2	D47R	Pathogenic	0.814
LRP5	O75197-1.2	D47S	Neutral	0.244
LRP5	O75197-1.2	D47T	Neutral	0.437
LRP5	O75197-1.2	D47V	Pathogenic	0.749
LRP5	O75197-1.2	D47W	Pathogenic	0.766
LRP5	O75197-1.2	D47Y	Pathogenic	0.78
LRP5	O75197-1.2	A48C	Neutral	0.194
LRP5	O75197-1.2	A48D	Pathogenic	0.606
LRP5	O75197-1.2	A48E	Neutral	0.356
LRP5	O75197-1.2	A48F	Neutral	0.5
LRP5	O75197-1.2	A48G	Neutral	0.25
LRP5	O75197-1.2	A48H	Pathogenic	0.767
LRP5	O75197-1.2	A48I	Neutral	0.248
LRP5	O75197-1.2	A48K	Neutral	0.279
LRP5	O75197-1.2	A48L	Neutral	0.266
LRP5	O75197-1.2	A48M	Neutral	0.355
LRP5	O75197-1.2	A48N	Pathogenic	0.639
LRP5	O75197-1.2	A48P	Neutral	0.479
LRP5	O75197-1.2	A48Q	Neutral	0.443
LRP5	O75197-1.2	A48R	Neutral	0.272
LRP5	O75197-1.2	A48S	Neutral	0.098
LRP5	O75197-1.2	A48T	Neutral	0.293
LRP5	O75197-1.2	A48V	Neutral	0.159
LRP5	O75197-1.2	A48W	Pathogenic	0.658
LRP5	O75197-1.2	A48Y	Pathogenic	0.675
LRP5	O75197-1.2	G49A	Neutral	0.008
LRP5	O75197-1.2	G49C	Neutral	0.103
LRP5	O75197-1.2	G49D	Neutral	0.015
LRP5	O75197-1.2	G49E	Neutral	0.047
LRP5	O75197-1.2	G49F	Neutral	0.049
LRP5	O75197-1.2	G49H	Neutral	0.071
LRP5	O75197-1.2	G49I	Neutral	0.136
LRP5	O75197-1.2	G49K	Neutral	0.033
LRP5	O75197-1.2	G49L	Neutral	0.147
LRP5	O75197-1.2	G49M	Neutral	0.079
LRP5	O75197-1.2	G49N	Neutral	0.006
LRP5	O75197-1.2	G49P	Neutral	0.045
LRP5	O75197-1.2	G49Q	Neutral	0.066
LRP5	O75197-1.2	G49R	Neutral	0.032
LRP5	O75197-1.2	G49S	Neutral	0.01
LRP5	O75197-1.2	G49T	Neutral	0.067
LRP5	O75197-1.2	G49V	Neutral	0.083
LRP5	O75197-1.2	G49W	Neutral	0.011
LRP5	O75197-1.2	G49Y	Neutral	0.097
LRP5	O75197-1.2	G50A	Neutral	0.007
LRP5	O75197-1.2	G50C	Neutral	0.096
LRP5	O75197-1.2	G50D	Neutral	0.014
LRP5	O75197-1.2	G50E	Neutral	0.044
LRP5	O75197-1.2	G50F	Neutral	0.045
LRP5	O75197-1.2	G50H	Neutral	0.066
LRP5	O75197-1.2	G50I	Neutral	0.127
LRP5	O75197-1.2	G50K	Neutral	0.031
LRP5	O75197-1.2	G50L	Neutral	0.137
LRP5	O75197-1.2	G50M	Neutral	0.074
LRP5	O75197-1.2	G50N	Neutral	0.005
LRP5	O75197-1.2	G50P	Neutral	0.042
LRP5	O75197-1.2	G50Q	Neutral	0.062
LRP5	O75197-1.2	G50R	Neutral	0.03
LRP5	O75197-1.2	G50S	Neutral	0.009
LRP5	O75197-1.2	G50T	Neutral	0.062
LRP5	O75197-1.2	G50V	Neutral	0.077
LRP5	O75197-1.2	G50W	Neutral	0.01
LRP5	O75197-1.2	G50Y	Neutral	0.09
LRP5	O75197-1.2	V51A	Neutral	0.003
LRP5	O75197-1.2	V51C	Neutral	0.016
LRP5	O75197-1.2	V51D	Neutral	0.03
LRP5	O75197-1.2	V51E	Neutral	0.012
LRP5	O75197-1.2	V51F	Neutral	0.011
LRP5	O75197-1.2	V51G	Neutral	0.055
LRP5	O75197-1.2	V51H	Neutral	0.065
LRP5	O75197-1.2	V51I	Neutral	0.0
LRP5	O75197-1.2	V51K	Neutral	0.008
LRP5	O75197-1.2	V51L	Neutral	0.001
LRP5	O75197-1.2	V51M	Neutral	0.002
LRP5	O75197-1.2	V51N	Neutral	0.035
LRP5	O75197-1.2	V51P	Neutral	0.037
LRP5	O75197-1.2	V51Q	Neutral	0.017
LRP5	O75197-1.2	V51R	Neutral	0.023
LRP5	O75197-1.2	V51S	Neutral	0.019
LRP5	O75197-1.2	V51T	Neutral	0.003
LRP5	O75197-1.2	V51W	Neutral	0.064
LRP5	O75197-1.2	V51Y	Neutral	0.015
LRP5	O75197-1.2	K52A	Neutral	0.215
LRP5	O75197-1.2	K52C	Pathogenic	0.588
LRP5	O75197-1.2	K52D	Neutral	0.427
LRP5	O75197-1.2	K52E	Neutral	0.069
LRP5	O75197-1.2	K52F	Neutral	0.429
LRP5	O75197-1.2	K52G	Pathogenic	0.515
LRP5	O75197-1.2	K52H	Neutral	0.258
LRP5	O75197-1.2	K52I	Neutral	0.421
LRP5	O75197-1.2	K52L	Neutral	0.208
LRP5	O75197-1.2	K52M	Neutral	0.116
LRP5	O75197-1.2	K52N	Neutral	0.175
LRP5	O75197-1.2	K52P	Neutral	0.164
LRP5	O75197-1.2	K52Q	Neutral	0.049
LRP5	O75197-1.2	K52R	Neutral	0.032
LRP5	O75197-1.2	K52S	Neutral	0.11
LRP5	O75197-1.2	K52T	Neutral	0.23
LRP5	O75197-1.2	K52V	Neutral	0.282
LRP5	O75197-1.2	K52W	Neutral	0.322
LRP5	O75197-1.2	K52Y	Neutral	0.339
LRP5	O75197-1.2	L53A	Neutral	0.003
LRP5	O75197-1.2	L53C	Neutral	0.005
LRP5	O75197-1.2	L53D	Neutral	0.027
LRP5	O75197-1.2	L53E	Neutral	0.011
LRP5	O75197-1.2	L53F	Neutral	0.003
LRP5	O75197-1.2	L53G	Neutral	0.049
LRP5	O75197-1.2	L53H	Neutral	0.021
LRP5	O75197-1.2	L53I	Neutral	0.0
LRP5	O75197-1.2	L53K	Neutral	0.003
LRP5	O75197-1.2	L53M	Neutral	0.0
LRP5	O75197-1.2	L53N	Neutral	0.011
LRP5	O75197-1.2	L53P	Neutral	0.034
LRP5	O75197-1.2	L53Q	Neutral	0.005
LRP5	O75197-1.2	L53R	Neutral	0.002
LRP5	O75197-1.2	L53S	Neutral	0.006
LRP5	O75197-1.2	L53T	Neutral	0.002
LRP5	O75197-1.2	L53V	Neutral	0.001
LRP5	O75197-1.2	L53W	Neutral	0.016
LRP5	O75197-1.2	L53Y	Neutral	0.005
LRP5	O75197-1.2	E54A	Neutral	0.105
LRP5	O75197-1.2	E54C	Pathogenic	0.65
LRP5	O75197-1.2	E54D	Neutral	0.009
LRP5	O75197-1.2	E54F	Neutral	0.228
LRP5	O75197-1.2	E54G	Neutral	0.313
LRP5	O75197-1.2	E54H	Neutral	0.045
LRP5	O75197-1.2	E54I	Neutral	0.229
LRP5	O75197-1.2	E54K	Neutral	0.022
LRP5	O75197-1.2	E54L	Neutral	0.246
LRP5	O75197-1.2	E54M	Neutral	0.14
LRP5	O75197-1.2	E54N	Neutral	0.083
LRP5	O75197-1.2	E54P	Neutral	0.078
LRP5	O75197-1.2	E54Q	Neutral	0.007
LRP5	O75197-1.2	E54R	Neutral	0.061
LRP5	O75197-1.2	E54S	Neutral	0.05
LRP5	O75197-1.2	E54T	Neutral	0.113
LRP5	O75197-1.2	E54V	Neutral	0.144
LRP5	O75197-1.2	E54W	Neutral	0.158
LRP5	O75197-1.2	E54Y	Neutral	0.168
LRP5	O75197-1.2	S55A	Neutral	0.009
LRP5	O75197-1.2	S55C	Neutral	0.044
LRP5	O75197-1.2	S55D	Neutral	0.019
LRP5	O75197-1.2	S55E	Neutral	0.021
LRP5	O75197-1.2	S55F	Neutral	0.059
LRP5	O75197-1.2	S55G	Neutral	0.034
LRP5	O75197-1.2	S55H	Neutral	0.085
LRP5	O75197-1.2	S55I	Neutral	0.059
LRP5	O75197-1.2	S55K	Neutral	0.015
LRP5	O75197-1.2	S55L	Neutral	0.065
LRP5	O75197-1.2	S55M	Neutral	0.033
LRP5	O75197-1.2	S55N	Neutral	0.007
LRP5	O75197-1.2	S55P	Neutral	0.055
LRP5	O75197-1.2	S55Q	Neutral	0.03
LRP5	O75197-1.2	S55R	Neutral	0.042
LRP5	O75197-1.2	S55T	Neutral	0.009
LRP5	O75197-1.2	S55V	Neutral	0.099
LRP5	O75197-1.2	S55W	Neutral	0.108
LRP5	O75197-1.2	S55Y	Neutral	0.115
LRP5	O75197-1.2	T56A	Neutral	0.325
LRP5	O75197-1.2	T56C	Neutral	0.453
LRP5	O75197-1.2	T56D	Neutral	0.389
LRP5	O75197-1.2	T56E	Neutral	0.412
LRP5	O75197-1.2	T56F	Pathogenic	0.536
LRP5	O75197-1.2	T56G	Pathogenic	0.783
LRP5	O75197-1.2	T56H	Pathogenic	0.807
LRP5	O75197-1.2	T56I	Neutral	0.276
LRP5	O75197-1.2	T56K	Neutral	0.329
LRP5	O75197-1.2	T56L	Neutral	0.295
LRP5	O75197-1.2	T56M	Neutral	0.389
LRP5	O75197-1.2	T56N	Neutral	0.196
LRP5	O75197-1.2	T56P	Pathogenic	0.513
LRP5	O75197-1.2	T56Q	Pathogenic	0.503
LRP5	O75197-1.2	T56R	Neutral	0.322
LRP5	O75197-1.2	T56S	Neutral	0.114
LRP5	O75197-1.2	T56V	Neutral	0.179
LRP5	O75197-1.2	T56W	Neutral	0.423
LRP5	O75197-1.2	T56Y	Pathogenic	0.706
LRP5	O75197-1.2	I57A	Neutral	0.134
LRP5	O75197-1.2	I57C	Neutral	0.226
LRP5	O75197-1.2	I57D	Neutral	0.362
LRP5	O75197-1.2	I57E	Neutral	0.397
LRP5	O75197-1.2	I57F	Neutral	0.171
LRP5	O75197-1.2	I57G	Pathogenic	0.763
LRP5	O75197-1.2	I57H	Pathogenic	0.571
LRP5	O75197-1.2	I57K	Neutral	0.326
LRP5	O75197-1.2	I57L	Neutral	0.021
LRP5	O75197-1.2	I57M	Neutral	0.04
LRP5	O75197-1.2	I57N	Neutral	0.4
LRP5	O75197-1.2	I57P	Pathogenic	0.682
LRP5	O75197-1.2	I57Q	Neutral	0.491
LRP5	O75197-1.2	I57R	Neutral	0.319
LRP5	O75197-1.2	I57S	Neutral	0.259
LRP5	O75197-1.2	I57T	Neutral	0.134
LRP5	O75197-1.2	I57V	Neutral	0.004
LRP5	O75197-1.2	I57W	Pathogenic	0.79
LRP5	O75197-1.2	I57Y	Neutral	0.228
LRP5	O75197-1.2	V58A	Neutral	0.284
LRP5	O75197-1.2	V58C	Pathogenic	0.695
LRP5	O75197-1.2	V58D	Pathogenic	0.816
LRP5	O75197-1.2	V58E	Pathogenic	0.625
LRP5	O75197-1.2	V58F	Pathogenic	0.623
LRP5	O75197-1.2	V58G	Pathogenic	0.892
LRP5	O75197-1.2	V58H	Pathogenic	0.909
LRP5	O75197-1.2	V58I	Neutral	0.019
LRP5	O75197-1.2	V58K	Pathogenic	0.538
LRP5	O75197-1.2	V58L	Neutral	0.164
LRP5	O75197-1.2	V58M	Neutral	0.23
LRP5	O75197-1.2	V58N	Pathogenic	0.839
LRP5	O75197-1.2	V58P	Pathogenic	0.846
LRP5	O75197-1.2	V58Q	Pathogenic	0.706
LRP5	O75197-1.2	V58R	Pathogenic	0.774
LRP5	O75197-1.2	V58S	Pathogenic	0.732
LRP5	O75197-1.2	V58T	Neutral	0.283
LRP5	O75197-1.2	V58W	Pathogenic	0.906
LRP5	O75197-1.2	V58Y	Pathogenic	0.685
LRP5	O75197-1.2	V59A	Neutral	0.225
LRP5	O75197-1.2	V59C	Pathogenic	0.625
LRP5	O75197-1.2	V59D	Pathogenic	0.764
LRP5	O75197-1.2	V59E	Pathogenic	0.55
LRP5	O75197-1.2	V59F	Pathogenic	0.548
LRP5	O75197-1.2	V59G	Pathogenic	0.858
LRP5	O75197-1.2	V59H	Pathogenic	0.879
LRP5	O75197-1.2	V59I	Neutral	0.014
LRP5	O75197-1.2	V59K	Neutral	0.461
LRP5	O75197-1.2	V59L	Neutral	0.126
LRP5	O75197-1.2	V59M	Neutral	0.18
LRP5	O75197-1.2	V59N	Pathogenic	0.792
LRP5	O75197-1.2	V59P	Pathogenic	0.801
LRP5	O75197-1.2	V59Q	Pathogenic	0.638
LRP5	O75197-1.2	V59R	Pathogenic	0.715
LRP5	O75197-1.2	V59S	Pathogenic	0.666
LRP5	O75197-1.2	V59T	Neutral	0.225
LRP5	O75197-1.2	V59W	Pathogenic	0.876
LRP5	O75197-1.2	V59Y	Pathogenic	0.614
LRP5	O75197-1.2	S60A	Neutral	0.015
LRP5	O75197-1.2	S60C	Neutral	0.072
LRP5	O75197-1.2	S60D	Neutral	0.032
LRP5	O75197-1.2	S60E	Neutral	0.035
LRP5	O75197-1.2	S60F	Neutral	0.096
LRP5	O75197-1.2	S60G	Neutral	0.057
LRP5	O75197-1.2	S60H	Neutral	0.136
LRP5	O75197-1.2	S60I	Neutral	0.096
LRP5	O75197-1.2	S60K	Neutral	0.024
LRP5	O75197-1.2	S60L	Neutral	0.105
LRP5	O75197-1.2	S60M	Neutral	0.055
LRP5	O75197-1.2	S60N	Neutral	0.012
LRP5	O75197-1.2	S60P	Neutral	0.089
LRP5	O75197-1.2	S60Q	Neutral	0.049
LRP5	O75197-1.2	S60R	Neutral	0.069
LRP5	O75197-1.2	S60T	Neutral	0.016
LRP5	O75197-1.2	S60V	Neutral	0.157
LRP5	O75197-1.2	S60W	Neutral	0.17
LRP5	O75197-1.2	S60Y	Neutral	0.181
LRP5	O75197-1.2	G61A	Neutral	0.172
LRP5	O75197-1.2	G61C	Pathogenic	0.756
LRP5	O75197-1.2	G61D	Neutral	0.286
LRP5	O75197-1.2	G61E	Pathogenic	0.572
LRP5	O75197-1.2	G61F	Pathogenic	0.582
LRP5	O75197-1.2	G61H	Pathogenic	0.674
LRP5	O75197-1.2	G61I	Pathogenic	0.81
LRP5	O75197-1.2	G61K	Neutral	0.483
LRP5	O75197-1.2	G61L	Pathogenic	0.823
LRP5	O75197-1.2	G61M	Pathogenic	0.7
LRP5	O75197-1.2	G61N	Neutral	0.132
LRP5	O75197-1.2	G61P	Pathogenic	0.561
LRP5	O75197-1.2	G61Q	Pathogenic	0.658
LRP5	O75197-1.2	G61R	Neutral	0.475
LRP5	O75197-1.2	G61S	Neutral	0.207
LRP5	O75197-1.2	G61T	Pathogenic	0.658
LRP5	O75197-1.2	G61V	Pathogenic	0.709
LRP5	O75197-1.2	G61W	Neutral	0.224
LRP5	O75197-1.2	G61Y	Pathogenic	0.743
LRP5	O75197-1.2	L62A	Pathogenic	0.675
LRP5	O75197-1.2	L62C	Pathogenic	0.796
LRP5	O75197-1.2	L62D	Pathogenic	0.959
LRP5	O75197-1.2	L62E	Pathogenic	0.898
LRP5	O75197-1.2	L62F	Pathogenic	0.702
LRP5	O75197-1.2	L62G	Pathogenic	0.977
LRP5	O75197-1.2	L62H	Pathogenic	0.947
LRP5	O75197-1.2	L62I	Neutral	0.204
LRP5	O75197-1.2	L62K	Pathogenic	0.681
LRP5	O75197-1.2	L62M	Neutral	0.156
LRP5	O75197-1.2	L62N	Pathogenic	0.899
LRP5	O75197-1.2	L62P	Pathogenic	0.966
LRP5	O75197-1.2	L62Q	Pathogenic	0.81
LRP5	O75197-1.2	L62R	Pathogenic	0.673
LRP5	O75197-1.2	L62S	Pathogenic	0.824
LRP5	O75197-1.2	L62T	Pathogenic	0.674
LRP5	O75197-1.2	L62V	Neutral	0.35
LRP5	O75197-1.2	L62W	Pathogenic	0.933
LRP5	O75197-1.2	L62Y	Pathogenic	0.799
LRP5	O75197-1.2	E63A	Pathogenic	0.659
LRP5	O75197-1.2	E63C	Pathogenic	0.968
LRP5	O75197-1.2	E63D	Neutral	0.129
LRP5	O75197-1.2	E63F	Pathogenic	0.83
LRP5	O75197-1.2	E63G	Pathogenic	0.882
LRP5	O75197-1.2	E63H	Neutral	0.439
LRP5	O75197-1.2	E63I	Pathogenic	0.83
LRP5	O75197-1.2	E63K	Neutral	0.267
LRP5	O75197-1.2	E63L	Pathogenic	0.843
LRP5	O75197-1.2	E63M	Pathogenic	0.729
LRP5	O75197-1.2	E63N	Pathogenic	0.6
LRP5	O75197-1.2	E63P	Pathogenic	0.581
LRP5	O75197-1.2	E63Q	Neutral	0.104
LRP5	O75197-1.2	E63R	Pathogenic	0.517
LRP5	O75197-1.2	E63S	Neutral	0.466
LRP5	O75197-1.2	E63T	Pathogenic	0.678
LRP5	O75197-1.2	E63V	Pathogenic	0.735
LRP5	O75197-1.2	E63W	Pathogenic	0.755
LRP5	O75197-1.2	E63Y	Pathogenic	0.769
LRP5	O75197-1.2	D64A	Pathogenic	0.791
LRP5	O75197-1.2	D64C	Pathogenic	0.867
LRP5	O75197-1.2	D64E	Neutral	0.094
LRP5	O75197-1.2	D64F	Pathogenic	0.748
LRP5	O75197-1.2	D64G	Pathogenic	0.614
LRP5	O75197-1.2	D64H	Pathogenic	0.592
LRP5	O75197-1.2	D64I	Pathogenic	0.749
LRP5	O75197-1.2	D64K	Pathogenic	0.722
LRP5	O75197-1.2	D64L	Pathogenic	0.909
LRP5	O75197-1.2	D64M	Pathogenic	0.833
LRP5	O75197-1.2	D64N	Neutral	0.238
LRP5	O75197-1.2	D64P	Neutral	0.473
LRP5	O75197-1.2	D64Q	Neutral	0.397
LRP5	O75197-1.2	D64R	Pathogenic	0.884
LRP5	O75197-1.2	D64S	Neutral	0.36
LRP5	O75197-1.2	D64T	Pathogenic	0.575
LRP5	O75197-1.2	D64V	Pathogenic	0.839
LRP5	O75197-1.2	D64W	Pathogenic	0.851
LRP5	O75197-1.2	D64Y	Pathogenic	0.861
LRP5	O75197-1.2	A65C	Neutral	0.459
LRP5	O75197-1.2	A65D	Pathogenic	0.844
LRP5	O75197-1.2	A65E	Pathogenic	0.661
LRP5	O75197-1.2	A65F	Pathogenic	0.779
LRP5	O75197-1.2	A65G	Pathogenic	0.54
LRP5	O75197-1.2	A65H	Pathogenic	0.921
LRP5	O75197-1.2	A65I	Pathogenic	0.538
LRP5	O75197-1.2	A65K	Pathogenic	0.577
LRP5	O75197-1.2	A65L	Pathogenic	0.56
LRP5	O75197-1.2	A65M	Pathogenic	0.66
LRP5	O75197-1.2	A65N	Pathogenic	0.862
LRP5	O75197-1.2	A65P	Pathogenic	0.764
LRP5	O75197-1.2	A65Q	Pathogenic	0.737
LRP5	O75197-1.2	A65R	Pathogenic	0.569
LRP5	O75197-1.2	A65S	Neutral	0.276
LRP5	O75197-1.2	A65T	Pathogenic	0.594
LRP5	O75197-1.2	A65V	Neutral	0.4
LRP5	O75197-1.2	A65W	Pathogenic	0.871
LRP5	O75197-1.2	A65Y	Pathogenic	0.88
LRP5	O75197-1.2	A66C	Pathogenic	0.571
LRP5	O75197-1.2	A66D	Pathogenic	0.895
LRP5	O75197-1.2	A66E	Pathogenic	0.754
LRP5	O75197-1.2	A66F	Pathogenic	0.847
LRP5	O75197-1.2	A66G	Pathogenic	0.649
LRP5	O75197-1.2	A66H	Pathogenic	0.948
LRP5	O75197-1.2	A66I	Pathogenic	0.646
LRP5	O75197-1.2	A66K	Pathogenic	0.682
LRP5	O75197-1.2	A66L	Pathogenic	0.667
LRP5	O75197-1.2	A66M	Pathogenic	0.753
LRP5	O75197-1.2	A66N	Pathogenic	0.908
LRP5	O75197-1.2	A66P	Pathogenic	0.836
LRP5	O75197-1.2	A66Q	Pathogenic	0.815
LRP5	O75197-1.2	A66R	Pathogenic	0.674
LRP5	O75197-1.2	A66S	Neutral	0.375
LRP5	O75197-1.2	A66T	Pathogenic	0.697
LRP5	O75197-1.2	A66V	Pathogenic	0.511
LRP5	O75197-1.2	A66W	Pathogenic	0.914
LRP5	O75197-1.2	A66Y	Pathogenic	0.92
LRP5	O75197-1.2	A67C	Pathogenic	0.615
LRP5	O75197-1.2	A67D	Pathogenic	0.911
LRP5	O75197-1.2	A67E	Pathogenic	0.786
LRP5	O75197-1.2	A67F	Pathogenic	0.869
LRP5	O75197-1.2	A67G	Pathogenic	0.689
LRP5	O75197-1.2	A67H	Pathogenic	0.956
LRP5	O75197-1.2	A67I	Pathogenic	0.687
LRP5	O75197-1.2	A67K	Pathogenic	0.72
LRP5	O75197-1.2	A67L	Pathogenic	0.706
LRP5	O75197-1.2	A67M	Pathogenic	0.785
LRP5	O75197-1.2	A67N	Pathogenic	0.922
LRP5	O75197-1.2	A67P	Pathogenic	0.859
LRP5	O75197-1.2	A67Q	Pathogenic	0.841
LRP5	O75197-1.2	A67R	Pathogenic	0.713
LRP5	O75197-1.2	A67S	Neutral	0.419
LRP5	O75197-1.2	A67T	Pathogenic	0.734
LRP5	O75197-1.2	A67V	Pathogenic	0.557
LRP5	O75197-1.2	A67W	Pathogenic	0.927
LRP5	O75197-1.2	A67Y	Pathogenic	0.932
LRP5	O75197-1.2	V68A	Neutral	0.269
LRP5	O75197-1.2	V68C	Pathogenic	0.678
LRP5	O75197-1.2	V68D	Pathogenic	0.804
LRP5	O75197-1.2	V68E	Pathogenic	0.607
LRP5	O75197-1.2	V68F	Pathogenic	0.605
LRP5	O75197-1.2	V68G	Pathogenic	0.884
LRP5	O75197-1.2	V68H	Pathogenic	0.902
LRP5	O75197-1.2	V68I	Neutral	0.018
LRP5	O75197-1.2	V68K	Pathogenic	0.519
LRP5	O75197-1.2	V68L	Neutral	0.154
LRP5	O75197-1.2	V68M	Neutral	0.217
LRP5	O75197-1.2	V68N	Pathogenic	0.828
LRP5	O75197-1.2	V68P	Pathogenic	0.836
LRP5	O75197-1.2	V68Q	Pathogenic	0.69
LRP5	O75197-1.2	V68R	Pathogenic	0.76
LRP5	O75197-1.2	V68S	Pathogenic	0.716
LRP5	O75197-1.2	V68T	Neutral	0.268
LRP5	O75197-1.2	V68W	Pathogenic	0.9
LRP5	O75197-1.2	V68Y	Pathogenic	0.668
LRP5	O75197-1.2	D69A	Pathogenic	0.918
LRP5	O75197-1.2	D69C	Pathogenic	0.95
LRP5	O75197-1.2	D69E	Neutral	0.234
LRP5	O75197-1.2	D69F	Pathogenic	0.897
LRP5	O75197-1.2	D69G	Pathogenic	0.824
LRP5	O75197-1.2	D69H	Pathogenic	0.81
LRP5	O75197-1.2	D69I	Pathogenic	0.898
LRP5	O75197-1.2	D69K	Pathogenic	0.884
LRP5	O75197-1.2	D69L	Pathogenic	0.967
LRP5	O75197-1.2	D69M	Pathogenic	0.936
LRP5	O75197-1.2	D69N	Neutral	0.479
LRP5	O75197-1.2	D69P	Pathogenic	0.725
LRP5	O75197-1.2	D69Q	Pathogenic	0.659
LRP5	O75197-1.2	D69R	Pathogenic	0.957
LRP5	O75197-1.2	D69S	Pathogenic	0.623
LRP5	O75197-1.2	D69T	Pathogenic	0.799
LRP5	O75197-1.2	D69V	Pathogenic	0.939
LRP5	O75197-1.2	D69W	Pathogenic	0.944
LRP5	O75197-1.2	D69Y	Pathogenic	0.948
LRP5	O75197-1.2	F70A	Pathogenic	0.883
LRP5	O75197-1.2	F70C	Pathogenic	0.934
LRP5	O75197-1.2	F70D	Pathogenic	0.901
LRP5	O75197-1.2	F70E	Pathogenic	0.913
LRP5	O75197-1.2	F70G	Pathogenic	0.944
LRP5	O75197-1.2	F70H	Pathogenic	0.696
LRP5	O75197-1.2	F70I	Pathogenic	0.768
LRP5	O75197-1.2	F70K	Pathogenic	0.889
LRP5	O75197-1.2	F70L	Pathogenic	0.756
LRP5	O75197-1.2	F70M	Pathogenic	0.67
LRP5	O75197-1.2	F70N	Pathogenic	0.914
LRP5	O75197-1.2	F70P	Pathogenic	0.99
LRP5	O75197-1.2	F70Q	Pathogenic	0.939
LRP5	O75197-1.2	F70R	Pathogenic	0.885
LRP5	O75197-1.2	F70S	Pathogenic	0.848
LRP5	O75197-1.2	F70T	Pathogenic	0.882
LRP5	O75197-1.2	F70V	Pathogenic	0.856
LRP5	O75197-1.2	F70W	Neutral	0.415
LRP5	O75197-1.2	F70Y	Neutral	0.054
LRP5	O75197-1.2	Q71A	Neutral	0.026
LRP5	O75197-1.2	Q71C	Neutral	0.121
LRP5	O75197-1.2	Q71D	Neutral	0.009
LRP5	O75197-1.2	Q71E	Neutral	0.001
LRP5	O75197-1.2	Q71F	Neutral	0.063
LRP5	O75197-1.2	Q71G	Neutral	0.093
LRP5	O75197-1.2	Q71H	Neutral	0.011
LRP5	O75197-1.2	Q71I	Neutral	0.064
LRP5	O75197-1.2	Q71K	Neutral	0.002
LRP5	O75197-1.2	Q71L	Neutral	0.024
LRP5	O75197-1.2	Q71M	Neutral	0.004
LRP5	O75197-1.2	Q71N	Neutral	0.01
LRP5	O75197-1.2	Q71P	Neutral	0.019
LRP5	O75197-1.2	Q71R	Neutral	0.002
LRP5	O75197-1.2	Q71S	Neutral	0.012
LRP5	O75197-1.2	Q71T	Neutral	0.028
LRP5	O75197-1.2	Q71V	Neutral	0.036
LRP5	O75197-1.2	Q71W	Neutral	0.014
LRP5	O75197-1.2	Q71Y	Neutral	0.015
LRP5	O75197-1.2	F72A	Pathogenic	0.703
LRP5	O75197-1.2	F72C	Pathogenic	0.817
LRP5	O75197-1.2	F72D	Pathogenic	0.74
LRP5	O75197-1.2	F72E	Pathogenic	0.767
LRP5	O75197-1.2	F72G	Pathogenic	0.841
LRP5	O75197-1.2	F72H	Neutral	0.419
LRP5	O75197-1.2	F72I	Pathogenic	0.509
LRP5	O75197-1.2	F72K	Pathogenic	0.715
LRP5	O75197-1.2	F72L	Neutral	0.493
LRP5	O75197-1.2	F72M	Neutral	0.39
LRP5	O75197-1.2	F72N	Pathogenic	0.77
LRP5	O75197-1.2	F72P	Pathogenic	0.97
LRP5	O75197-1.2	F72Q	Pathogenic	0.829
LRP5	O75197-1.2	F72R	Pathogenic	0.708
LRP5	O75197-1.2	F72S	Pathogenic	0.637
LRP5	O75197-1.2	F72T	Pathogenic	0.702
LRP5	O75197-1.2	F72V	Pathogenic	0.65
LRP5	O75197-1.2	F72W	Neutral	0.182
LRP5	O75197-1.2	F72Y	Neutral	0.018
LRP5	O75197-1.2	S73A	Neutral	0.006
LRP5	O75197-1.2	S73C	Neutral	0.028
LRP5	O75197-1.2	S73D	Neutral	0.012
LRP5	O75197-1.2	S73E	Neutral	0.013
LRP5	O75197-1.2	S73F	Neutral	0.038
LRP5	O75197-1.2	S73G	Neutral	0.022
LRP5	O75197-1.2	S73H	Neutral	0.055
LRP5	O75197-1.2	S73I	Neutral	0.038
LRP5	O75197-1.2	S73K	Neutral	0.009
LRP5	O75197-1.2	S73L	Neutral	0.042
LRP5	O75197-1.2	S73M	Neutral	0.021
LRP5	O75197-1.2	S73N	Neutral	0.005
LRP5	O75197-1.2	S73P	Neutral	0.035
LRP5	O75197-1.2	S73Q	Neutral	0.019
LRP5	O75197-1.2	S73R	Neutral	0.027
LRP5	O75197-1.2	S73T	Neutral	0.006
LRP5	O75197-1.2	S73V	Neutral	0.064
LRP5	O75197-1.2	S73W	Neutral	0.07
LRP5	O75197-1.2	S73Y	Neutral	0.076
LRP5	O75197-1.2	K74A	Neutral	0.023
LRP5	O75197-1.2	K74C	Neutral	0.107
LRP5	O75197-1.2	K74D	Neutral	0.059
LRP5	O75197-1.2	K74E	Neutral	0.006
LRP5	O75197-1.2	K74F	Neutral	0.06
LRP5	O75197-1.2	K74G	Neutral	0.082
LRP5	O75197-1.2	K74H	Neutral	0.028
LRP5	O75197-1.2	K74I	Neutral	0.058
LRP5	O75197-1.2	K74L	Neutral	0.022
LRP5	O75197-1.2	K74M	Neutral	0.011
LRP5	O75197-1.2	K74N	Neutral	0.018
LRP5	O75197-1.2	K74P	Neutral	0.016
LRP5	O75197-1.2	K74Q	Neutral	0.004
LRP5	O75197-1.2	K74R	Neutral	0.003
LRP5	O75197-1.2	K74S	Neutral	0.01
LRP5	O75197-1.2	K74T	Neutral	0.025
LRP5	O75197-1.2	K74V	Neutral	0.032
LRP5	O75197-1.2	K74W	Neutral	0.038
LRP5	O75197-1.2	K74Y	Neutral	0.041
LRP5	O75197-1.2	G75A	Neutral	0.235
LRP5	O75197-1.2	G75C	Pathogenic	0.821
LRP5	O75197-1.2	G75D	Neutral	0.373
LRP5	O75197-1.2	G75E	Pathogenic	0.664
LRP5	O75197-1.2	G75F	Pathogenic	0.673
LRP5	O75197-1.2	G75H	Pathogenic	0.754
LRP5	O75197-1.2	G75I	Pathogenic	0.863
LRP5	O75197-1.2	G75K	Pathogenic	0.581
LRP5	O75197-1.2	G75L	Pathogenic	0.874
LRP5	O75197-1.2	G75M	Pathogenic	0.775
LRP5	O75197-1.2	G75N	Neutral	0.184
LRP5	O75197-1.2	G75P	Pathogenic	0.655
LRP5	O75197-1.2	G75Q	Pathogenic	0.74
LRP5	O75197-1.2	G75R	Pathogenic	0.572
LRP5	O75197-1.2	G75S	Neutral	0.279
LRP5	O75197-1.2	G75T	Pathogenic	0.741
LRP5	O75197-1.2	G75V	Pathogenic	0.783
LRP5	O75197-1.2	G75W	Neutral	0.3
LRP5	O75197-1.2	G75Y	Pathogenic	0.811
LRP5	O75197-1.2	A76C	Neutral	0.005
LRP5	O75197-1.2	A76D	Neutral	0.029
LRP5	O75197-1.2	A76E	Neutral	0.011
LRP5	O75197-1.2	A76F	Neutral	0.019
LRP5	O75197-1.2	A76G	Neutral	0.006
LRP5	O75197-1.2	A76H	Neutral	0.06
LRP5	O75197-1.2	A76I	Neutral	0.006
LRP5	O75197-1.2	A76K	Neutral	0.007
LRP5	O75197-1.2	A76L	Neutral	0.007
LRP5	O75197-1.2	A76M	Neutral	0.011
LRP5	O75197-1.2	A76N	Neutral	0.033
LRP5	O75197-1.2	A76P	Neutral	0.017
LRP5	O75197-1.2	A76Q	Neutral	0.015
LRP5	O75197-1.2	A76R	Neutral	0.007
LRP5	O75197-1.2	A76S	Neutral	0.002
LRP5	O75197-1.2	A76T	Neutral	0.008
LRP5	O75197-1.2	A76V	Neutral	0.004
LRP5	O75197-1.2	A76W	Neutral	0.036
LRP5	O75197-1.2	A76Y	Neutral	0.039
LRP5	O75197-1.2	V77A	Neutral	0.08
LRP5	O75197-1.2	V77C	Neutral	0.333
LRP5	O75197-1.2	V77D	Neutral	0.493
LRP5	O75197-1.2	V77E	Neutral	0.268
LRP5	O75197-1.2	V77F	Neutral	0.266
LRP5	O75197-1.2	V77G	Pathogenic	0.644
LRP5	O75197-1.2	V77H	Pathogenic	0.686
LRP5	O75197-1.2	V77I	Neutral	0.004
LRP5	O75197-1.2	V77K	Neutral	0.204
LRP5	O75197-1.2	V77L	Neutral	0.041
LRP5	O75197-1.2	V77M	Neutral	0.062
LRP5	O75197-1.2	V77N	Pathogenic	0.533
LRP5	O75197-1.2	V77P	Pathogenic	0.547
LRP5	O75197-1.2	V77Q	Neutral	0.345
LRP5	O75197-1.2	V77R	Neutral	0.429
LRP5	O75197-1.2	V77S	Neutral	0.374
LRP5	O75197-1.2	V77T	Neutral	0.08
LRP5	O75197-1.2	V77W	Pathogenic	0.68
LRP5	O75197-1.2	V77Y	Neutral	0.323
LRP5	O75197-1.2	Y78A	Pathogenic	0.717
LRP5	O75197-1.2	Y78C	Pathogenic	0.821
LRP5	O75197-1.2	Y78D	Pathogenic	0.753
LRP5	O75197-1.2	Y78E	Pathogenic	0.538
LRP5	O75197-1.2	Y78F	Neutral	0.009
LRP5	O75197-1.2	Y78G	Pathogenic	0.85
LRP5	O75197-1.2	Y78H	Neutral	0.027
LRP5	O75197-1.2	Y78I	Neutral	0.435
LRP5	O75197-1.2	Y78K	Neutral	0.469
LRP5	O75197-1.2	Y78L	Neutral	0.457
LRP5	O75197-1.2	Y78M	Pathogenic	0.562
LRP5	O75197-1.2	Y78N	Pathogenic	0.541
LRP5	O75197-1.2	Y78P	Pathogenic	0.92
LRP5	O75197-1.2	Y78Q	Neutral	0.359
LRP5	O75197-1.2	Y78R	Neutral	0.466
LRP5	O75197-1.2	Y78S	Pathogenic	0.653
LRP5	O75197-1.2	Y78T	Pathogenic	0.716
LRP5	O75197-1.2	Y78V	Pathogenic	0.558
LRP5	O75197-1.2	Y78W	Neutral	0.018
LRP5	O75197-1.2	W79A	Pathogenic	0.989
LRP5	O75197-1.2	W79C	Pathogenic	0.983
LRP5	O75197-1.2	W79D	Pathogenic	0.991
LRP5	O75197-1.2	W79E	Pathogenic	0.977
LRP5	O75197-1.2	W79F	Pathogenic	0.818
LRP5	O75197-1.2	W79G	Pathogenic	0.957
LRP5	O75197-1.2	W79H	Pathogenic	0.966
LRP5	O75197-1.2	W79I	Pathogenic	0.997
LRP5	O75197-1.2	W79K	Pathogenic	0.97
LRP5	O75197-1.2	W79L	Pathogenic	0.991
LRP5	O75197-1.2	W79M	Pathogenic	0.961
LRP5	O75197-1.2	W79N	Pathogenic	0.992
LRP5	O75197-1.2	W79P	Pathogenic	0.998
LRP5	O75197-1.2	W79Q	Pathogenic	0.953
LRP5	O75197-1.2	W79R	Pathogenic	0.97
LRP5	O75197-1.2	W79S	Pathogenic	0.986
LRP5	O75197-1.2	W79T	Pathogenic	0.968
LRP5	O75197-1.2	W79V	Pathogenic	0.995
LRP5	O75197-1.2	W79Y	Neutral	0.416
LRP5	O75197-1.2	T80A	Neutral	0.216
LRP5	O75197-1.2	T80C	Neutral	0.322
LRP5	O75197-1.2	T80D	Neutral	0.268
LRP5	O75197-1.2	T80E	Neutral	0.287
LRP5	O75197-1.2	T80F	Neutral	0.399
LRP5	O75197-1.2	T80G	Pathogenic	0.674
LRP5	O75197-1.2	T80H	Pathogenic	0.706
LRP5	O75197-1.2	T80I	Neutral	0.18
LRP5	O75197-1.2	T80K	Neutral	0.22
LRP5	O75197-1.2	T80L	Neutral	0.194
LRP5	O75197-1.2	T80M	Neutral	0.267
LRP5	O75197-1.2	T80N	Neutral	0.122
LRP5	O75197-1.2	T80P	Neutral	0.377
LRP5	O75197-1.2	T80Q	Neutral	0.367
LRP5	O75197-1.2	T80R	Neutral	0.214
LRP5	O75197-1.2	T80S	Neutral	0.069
LRP5	O75197-1.2	T80V	Neutral	0.111
LRP5	O75197-1.2	T80W	Neutral	0.295
LRP5	O75197-1.2	T80Y	Pathogenic	0.579
LRP5	O75197-1.2	D81A	Pathogenic	0.944
LRP5	O75197-1.2	D81C	Pathogenic	0.966
LRP5	O75197-1.2	D81E	Neutral	0.316
LRP5	O75197-1.2	D81F	Pathogenic	0.929
LRP5	O75197-1.2	D81G	Pathogenic	0.876
LRP5	O75197-1.2	D81H	Pathogenic	0.865
LRP5	O75197-1.2	D81I	Pathogenic	0.93
LRP5	O75197-1.2	D81K	Pathogenic	0.92
LRP5	O75197-1.2	D81L	Pathogenic	0.978
LRP5	O75197-1.2	D81M	Pathogenic	0.957
LRP5	O75197-1.2	D81N	Pathogenic	0.581
LRP5	O75197-1.2	D81P	Pathogenic	0.799
LRP5	O75197-1.2	D81Q	Pathogenic	0.744
LRP5	O75197-1.2	D81R	Pathogenic	0.971
LRP5	O75197-1.2	D81S	Pathogenic	0.714
LRP5	O75197-1.2	D81T	Pathogenic	0.857
LRP5	O75197-1.2	D81V	Pathogenic	0.958
LRP5	O75197-1.2	D81W	Pathogenic	0.962
LRP5	O75197-1.2	D81Y	Pathogenic	0.965
LRP5	O75197-1.2	V82A	Neutral	0.376
LRP5	O75197-1.2	V82C	Pathogenic	0.775
LRP5	O75197-1.2	V82D	Pathogenic	0.87
LRP5	O75197-1.2	V82E	Pathogenic	0.716
LRP5	O75197-1.2	V82F	Pathogenic	0.715
LRP5	O75197-1.2	V82G	Pathogenic	0.926
LRP5	O75197-1.2	V82H	Pathogenic	0.938
LRP5	O75197-1.2	V82I	Neutral	0.029
LRP5	O75197-1.2	V82K	Pathogenic	0.639
LRP5	O75197-1.2	V82L	Neutral	0.23
LRP5	O75197-1.2	V82M	Neutral	0.312
LRP5	O75197-1.2	V82N	Pathogenic	0.887
LRP5	O75197-1.2	V82P	Pathogenic	0.893
LRP5	O75197-1.2	V82Q	Pathogenic	0.784
LRP5	O75197-1.2	V82R	Pathogenic	0.839
LRP5	O75197-1.2	V82S	Pathogenic	0.805
LRP5	O75197-1.2	V82T	Neutral	0.375
LRP5	O75197-1.2	V82W	Pathogenic	0.936
LRP5	O75197-1.2	V82Y	Pathogenic	0.767
LRP5	O75197-1.2	S83A	Neutral	0.162
LRP5	O75197-1.2	S83C	Neutral	0.491
LRP5	O75197-1.2	S83D	Neutral	0.289
LRP5	O75197-1.2	S83E	Neutral	0.308
LRP5	O75197-1.2	S83F	Pathogenic	0.569
LRP5	O75197-1.2	S83G	Neutral	0.428
LRP5	O75197-1.2	S83H	Pathogenic	0.662
LRP5	O75197-1.2	S83I	Pathogenic	0.57
LRP5	O75197-1.2	S83K	Neutral	0.237
LRP5	O75197-1.2	S83L	Pathogenic	0.592
LRP5	O75197-1.2	S83M	Neutral	0.421
LRP5	O75197-1.2	S83N	Neutral	0.133
LRP5	O75197-1.2	S83P	Pathogenic	0.548
LRP5	O75197-1.2	S83Q	Neutral	0.39
LRP5	O75197-1.2	S83R	Neutral	0.478
LRP5	O75197-1.2	S83T	Neutral	0.165
LRP5	O75197-1.2	S83V	Pathogenic	0.698
LRP5	O75197-1.2	S83W	Pathogenic	0.717
LRP5	O75197-1.2	S83Y	Pathogenic	0.733
LRP5	O75197-1.2	E84A	Pathogenic	0.658
LRP5	O75197-1.2	E84C	Pathogenic	0.968
LRP5	O75197-1.2	E84D	Neutral	0.128
LRP5	O75197-1.2	E84F	Pathogenic	0.83
LRP5	O75197-1.2	E84G	Pathogenic	0.882
LRP5	O75197-1.2	E84H	Neutral	0.439
LRP5	O75197-1.2	E84I	Pathogenic	0.83
LRP5	O75197-1.2	E84K	Neutral	0.266
LRP5	O75197-1.2	E84L	Pathogenic	0.843
LRP5	O75197-1.2	E84M	Pathogenic	0.728
LRP5	O75197-1.2	E84N	Pathogenic	0.599
LRP5	O75197-1.2	E84P	Pathogenic	0.581
LRP5	O75197-1.2	E84Q	Neutral	0.104
LRP5	O75197-1.2	E84R	Pathogenic	0.516
LRP5	O75197-1.2	E84S	Neutral	0.465
LRP5	O75197-1.2	E84T	Pathogenic	0.678
LRP5	O75197-1.2	E84V	Pathogenic	0.734
LRP5	O75197-1.2	E84W	Pathogenic	0.755
LRP5	O75197-1.2	E84Y	Pathogenic	0.769
LRP5	O75197-1.2	E85A	Pathogenic	0.917
LRP5	O75197-1.2	E85C	Pathogenic	0.994
LRP5	O75197-1.2	E85D	Neutral	0.457
LRP5	O75197-1.2	E85F	Pathogenic	0.965
LRP5	O75197-1.2	E85G	Pathogenic	0.977
LRP5	O75197-1.2	E85H	Pathogenic	0.817
LRP5	O75197-1.2	E85I	Pathogenic	0.965
LRP5	O75197-1.2	E85K	Pathogenic	0.675
LRP5	O75197-1.2	E85L	Pathogenic	0.968
LRP5	O75197-1.2	E85M	Pathogenic	0.939
LRP5	O75197-1.2	E85N	Pathogenic	0.895
LRP5	O75197-1.2	E85P	Pathogenic	0.888
LRP5	O75197-1.2	E85Q	Neutral	0.399
LRP5	O75197-1.2	E85R	Pathogenic	0.859
LRP5	O75197-1.2	E85S	Pathogenic	0.832
LRP5	O75197-1.2	E85T	Pathogenic	0.923
LRP5	O75197-1.2	E85V	Pathogenic	0.94
LRP5	O75197-1.2	E85W	Pathogenic	0.946
LRP5	O75197-1.2	E85Y	Pathogenic	0.95
LRP5	O75197-1.2	A86C	Neutral	0.131
LRP5	O75197-1.2	A86D	Neutral	0.491
LRP5	O75197-1.2	A86E	Neutral	0.257
LRP5	O75197-1.2	A86F	Neutral	0.385
LRP5	O75197-1.2	A86G	Neutral	0.173
LRP5	O75197-1.2	A86H	Pathogenic	0.674
LRP5	O75197-1.2	A86I	Neutral	0.171
LRP5	O75197-1.2	A86K	Neutral	0.195
LRP5	O75197-1.2	A86L	Neutral	0.185
LRP5	O75197-1.2	A86M	Neutral	0.257
LRP5	O75197-1.2	A86N	Pathogenic	0.527
LRP5	O75197-1.2	A86P	Neutral	0.366
LRP5	O75197-1.2	A86Q	Neutral	0.333
LRP5	O75197-1.2	A86R	Neutral	0.19
LRP5	O75197-1.2	A86S	Neutral	0.064
LRP5	O75197-1.2	A86T	Neutral	0.206
LRP5	O75197-1.2	A86V	Neutral	0.106
LRP5	O75197-1.2	A86W	Pathogenic	0.547
LRP5	O75197-1.2	A86Y	Pathogenic	0.566
LRP5	O75197-1.2	I87A	Pathogenic	0.842
LRP5	O75197-1.2	I87C	Pathogenic	0.909
LRP5	O75197-1.2	I87D	Pathogenic	0.951
LRP5	O75197-1.2	I87E	Pathogenic	0.958
LRP5	O75197-1.2	I87F	Pathogenic	0.876
LRP5	O75197-1.2	I87G	Pathogenic	0.991
LRP5	O75197-1.2	I87H	Pathogenic	0.979
LRP5	O75197-1.2	I87K	Pathogenic	0.943
LRP5	O75197-1.2	I87L	Neutral	0.418
LRP5	O75197-1.2	I87M	Pathogenic	0.59
LRP5	O75197-1.2	I87N	Pathogenic	0.958
LRP5	O75197-1.2	I87P	Pathogenic	0.987
LRP5	O75197-1.2	I87Q	Pathogenic	0.971
LRP5	O75197-1.2	I87R	Pathogenic	0.941
LRP5	O75197-1.2	I87S	Pathogenic	0.923
LRP5	O75197-1.2	I87T	Pathogenic	0.841
LRP5	O75197-1.2	I87V	Neutral	0.13
LRP5	O75197-1.2	I87W	Pathogenic	0.992
LRP5	O75197-1.2	I87Y	Pathogenic	0.91
LRP5	O75197-1.2	K88A	Pathogenic	0.719
LRP5	O75197-1.2	K88C	Pathogenic	0.93
LRP5	O75197-1.2	K88D	Pathogenic	0.874
LRP5	O75197-1.2	K88E	Neutral	0.407
LRP5	O75197-1.2	K88F	Pathogenic	0.875
LRP5	O75197-1.2	K88G	Pathogenic	0.908
LRP5	O75197-1.2	K88H	Pathogenic	0.764
LRP5	O75197-1.2	K88I	Pathogenic	0.872
LRP5	O75197-1.2	K88L	Pathogenic	0.71
LRP5	O75197-1.2	K88M	Pathogenic	0.55
LRP5	O75197-1.2	K88N	Pathogenic	0.665
LRP5	O75197-1.2	K88P	Pathogenic	0.647
LRP5	O75197-1.2	K88Q	Neutral	0.323
LRP5	O75197-1.2	K88R	Neutral	0.238
LRP5	O75197-1.2	K88S	Pathogenic	0.536
LRP5	O75197-1.2	K88T	Pathogenic	0.736
LRP5	O75197-1.2	K88V	Pathogenic	0.785
LRP5	O75197-1.2	K88W	Pathogenic	0.816
LRP5	O75197-1.2	K88Y	Pathogenic	0.827
LRP5	O75197-1.2	Q89A	Neutral	0.245
LRP5	O75197-1.2	Q89C	Pathogenic	0.628
LRP5	O75197-1.2	Q89D	Neutral	0.098
LRP5	O75197-1.2	Q89E	Neutral	0.013
LRP5	O75197-1.2	Q89F	Neutral	0.454
LRP5	O75197-1.2	Q89G	Pathogenic	0.557
LRP5	O75197-1.2	Q89H	Neutral	0.118
LRP5	O75197-1.2	Q89I	Neutral	0.455
LRP5	O75197-1.2	Q89K	Neutral	0.029
LRP5	O75197-1.2	Q89L	Neutral	0.231
LRP5	O75197-1.2	Q89M	Neutral	0.047
LRP5	O75197-1.2	Q89N	Neutral	0.113
LRP5	O75197-1.2	Q89P	Neutral	0.189
LRP5	O75197-1.2	Q89R	Neutral	0.028
LRP5	O75197-1.2	Q89S	Neutral	0.128
LRP5	O75197-1.2	Q89T	Neutral	0.261
LRP5	O75197-1.2	Q89V	Neutral	0.317
LRP5	O75197-1.2	Q89W	Neutral	0.147
LRP5	O75197-1.2	Q89Y	Neutral	0.157
LRP5	O75197-1.2	T90A	Neutral	0.311
LRP5	O75197-1.2	T90C	Neutral	0.437
LRP5	O75197-1.2	T90D	Neutral	0.374
LRP5	O75197-1.2	T90E	Neutral	0.397
LRP5	O75197-1.2	T90F	Pathogenic	0.52
LRP5	O75197-1.2	T90G	Pathogenic	0.772
LRP5	O75197-1.2	T90H	Pathogenic	0.797
LRP5	O75197-1.2	T90I	Neutral	0.264
LRP5	O75197-1.2	T90K	Neutral	0.315
LRP5	O75197-1.2	T90L	Neutral	0.282
LRP5	O75197-1.2	T90M	Neutral	0.374
LRP5	O75197-1.2	T90N	Neutral	0.186
LRP5	O75197-1.2	T90P	Neutral	0.497
LRP5	O75197-1.2	T90Q	Neutral	0.487
LRP5	O75197-1.2	T90R	Neutral	0.308
LRP5	O75197-1.2	T90S	Neutral	0.108
LRP5	O75197-1.2	T90V	Neutral	0.17
LRP5	O75197-1.2	T90W	Neutral	0.407
LRP5	O75197-1.2	T90Y	Pathogenic	0.693
LRP5	O75197-1.2	Y91A	Neutral	0.082
LRP5	O75197-1.2	Y91C	Neutral	0.14
LRP5	O75197-1.2	Y91D	Neutral	0.098
LRP5	O75197-1.2	Y91E	Neutral	0.04
LRP5	O75197-1.2	Y91F	Neutral	0.0
LRP5	O75197-1.2	Y91G	Neutral	0.168
LRP5	O75197-1.2	Y91H	Neutral	0.001
LRP5	O75197-1.2	Y91I	Neutral	0.027
LRP5	O75197-1.2	Y91K	Neutral	0.03
LRP5	O75197-1.2	Y91L	Neutral	0.029
LRP5	O75197-1.2	Y91M	Neutral	0.044
LRP5	O75197-1.2	Y91N	Neutral	0.04
LRP5	O75197-1.2	Y91P	Neutral	0.291
LRP5	O75197-1.2	Y91Q	Neutral	0.019
LRP5	O75197-1.2	Y91R	Neutral	0.03
LRP5	O75197-1.2	Y91S	Neutral	0.063
LRP5	O75197-1.2	Y91T	Neutral	0.082
LRP5	O75197-1.2	Y91V	Neutral	0.043
LRP5	O75197-1.2	Y91W	Neutral	0.001
LRP5	O75197-1.2	L92A	Neutral	0.004
LRP5	O75197-1.2	L92C	Neutral	0.007
LRP5	O75197-1.2	L92D	Neutral	0.04
LRP5	O75197-1.2	L92E	Neutral	0.016
LRP5	O75197-1.2	L92F	Neutral	0.004
LRP5	O75197-1.2	L92G	Neutral	0.072
LRP5	O75197-1.2	L92H	Neutral	0.031
LRP5	O75197-1.2	L92I	Neutral	0.0
LRP5	O75197-1.2	L92K	Neutral	0.004
LRP5	O75197-1.2	L92M	Neutral	0.0
LRP5	O75197-1.2	L92N	Neutral	0.016
LRP5	O75197-1.2	L92P	Neutral	0.049
LRP5	O75197-1.2	L92Q	Neutral	0.008
LRP5	O75197-1.2	L92R	Neutral	0.004
LRP5	O75197-1.2	L92S	Neutral	0.008
LRP5	O75197-1.2	L92T	Neutral	0.004
LRP5	O75197-1.2	L92V	Neutral	0.001
LRP5	O75197-1.2	L92W	Neutral	0.024
LRP5	O75197-1.2	L92Y	Neutral	0.007
LRP5	O75197-1.2	N93A	Pathogenic	0.954
LRP5	O75197-1.2	N93C	Pathogenic	0.973
LRP5	O75197-1.2	N93D	Pathogenic	0.6
LRP5	O75197-1.2	N93E	Pathogenic	0.835
LRP5	O75197-1.2	N93F	Pathogenic	0.943
LRP5	O75197-1.2	N93G	Pathogenic	0.743
LRP5	O75197-1.2	N93H	Neutral	0.468
LRP5	O75197-1.2	N93I	Pathogenic	0.944
LRP5	O75197-1.2	N93K	Pathogenic	0.78
LRP5	O75197-1.2	N93L	Pathogenic	0.948
LRP5	O75197-1.2	N93M	Pathogenic	0.902
LRP5	O75197-1.2	N93P	Pathogenic	0.938
LRP5	O75197-1.2	N93Q	Pathogenic	0.787
LRP5	O75197-1.2	N93R	Pathogenic	0.774
LRP5	O75197-1.2	N93S	Pathogenic	0.505
LRP5	O75197-1.2	N93T	Pathogenic	0.712
LRP5	O75197-1.2	N93V	Pathogenic	0.967
LRP5	O75197-1.2	N93W	Pathogenic	0.97
LRP5	O75197-1.2	N93Y	Pathogenic	0.919
LRP5	O75197-1.2	Q94A	Neutral	0.115
LRP5	O75197-1.2	Q94C	Neutral	0.403
LRP5	O75197-1.2	Q94D	Neutral	0.042
LRP5	O75197-1.2	Q94E	Neutral	0.005
LRP5	O75197-1.2	Q94F	Neutral	0.25
LRP5	O75197-1.2	Q94G	Neutral	0.335
LRP5	O75197-1.2	Q94H	Neutral	0.051
LRP5	O75197-1.2	Q94I	Neutral	0.25
LRP5	O75197-1.2	Q94K	Neutral	0.012
LRP5	O75197-1.2	Q94L	Neutral	0.107
LRP5	O75197-1.2	Q94M	Neutral	0.019
LRP5	O75197-1.2	Q94N	Neutral	0.048
LRP5	O75197-1.2	Q94P	Neutral	0.085
LRP5	O75197-1.2	Q94R	Neutral	0.011
LRP5	O75197-1.2	Q94S	Neutral	0.055
LRP5	O75197-1.2	Q94T	Neutral	0.124
LRP5	O75197-1.2	Q94V	Neutral	0.157
LRP5	O75197-1.2	Q94W	Neutral	0.065
LRP5	O75197-1.2	Q94Y	Neutral	0.069
LRP5	O75197-1.2	T95A	Neutral	0.281
LRP5	O75197-1.2	T95C	Neutral	0.402
LRP5	O75197-1.2	T95D	Neutral	0.341
LRP5	O75197-1.2	T95E	Neutral	0.363
LRP5	O75197-1.2	T95F	Neutral	0.484
LRP5	O75197-1.2	T95G	Pathogenic	0.745
LRP5	O75197-1.2	T95H	Pathogenic	0.773
LRP5	O75197-1.2	T95I	Neutral	0.237
LRP5	O75197-1.2	T95K	Neutral	0.285
LRP5	O75197-1.2	T95L	Neutral	0.254
LRP5	O75197-1.2	T95M	Neutral	0.341
LRP5	O75197-1.2	T95N	Neutral	0.165
LRP5	O75197-1.2	T95P	Neutral	0.461
LRP5	O75197-1.2	T95Q	Neutral	0.451
LRP5	O75197-1.2	T95R	Neutral	0.278
LRP5	O75197-1.2	T95S	Neutral	0.095
LRP5	O75197-1.2	T95V	Neutral	0.151
LRP5	O75197-1.2	T95W	Neutral	0.373
LRP5	O75197-1.2	T95Y	Pathogenic	0.661
LRP5	O75197-1.2	G96A	Neutral	0.118
LRP5	O75197-1.2	G96C	Pathogenic	0.666
LRP5	O75197-1.2	G96D	Neutral	0.206
LRP5	O75197-1.2	G96E	Neutral	0.463
LRP5	O75197-1.2	G96F	Neutral	0.473
LRP5	O75197-1.2	G96H	Pathogenic	0.571
LRP5	O75197-1.2	G96I	Pathogenic	0.733
LRP5	O75197-1.2	G96K	Neutral	0.376
LRP5	O75197-1.2	G96L	Pathogenic	0.75
LRP5	O75197-1.2	G96M	Pathogenic	0.6
LRP5	O75197-1.2	G96N	Neutral	0.089
LRP5	O75197-1.2	G96P	Neutral	0.452
LRP5	O75197-1.2	G96Q	Pathogenic	0.554
LRP5	O75197-1.2	G96R	Neutral	0.368
LRP5	O75197-1.2	G96S	Neutral	0.144
LRP5	O75197-1.2	G96T	Pathogenic	0.554
LRP5	O75197-1.2	G96V	Pathogenic	0.611
LRP5	O75197-1.2	G96W	Neutral	0.157
LRP5	O75197-1.2	G96Y	Pathogenic	0.651
LRP5	O75197-1.2	A97C	Neutral	0.002
LRP5	O75197-1.2	A97D	Neutral	0.011
LRP5	O75197-1.2	A97E	Neutral	0.004
LRP5	O75197-1.2	A97F	Neutral	0.007
LRP5	O75197-1.2	A97G	Neutral	0.002
LRP5	O75197-1.2	A97H	Neutral	0.022
LRP5	O75197-1.2	A97I	Neutral	0.002
LRP5	O75197-1.2	A97K	Neutral	0.003
LRP5	O75197-1.2	A97L	Neutral	0.002
LRP5	O75197-1.2	A97M	Neutral	0.004
LRP5	O75197-1.2	A97N	Neutral	0.012
LRP5	O75197-1.2	A97P	Neutral	0.006
LRP5	O75197-1.2	A97Q	Neutral	0.005
LRP5	O75197-1.2	A97R	Neutral	0.003
LRP5	O75197-1.2	A97S	Neutral	0.001
LRP5	O75197-1.2	A97T	Neutral	0.003
LRP5	O75197-1.2	A97V	Neutral	0.001
LRP5	O75197-1.2	A97W	Neutral	0.013
LRP5	O75197-1.2	A97Y	Neutral	0.014
LRP5	O75197-1.2	A98C	Neutral	0.001
LRP5	O75197-1.2	A98D	Neutral	0.007
LRP5	O75197-1.2	A98E	Neutral	0.002
LRP5	O75197-1.2	A98F	Neutral	0.004
LRP5	O75197-1.2	A98G	Neutral	0.001
LRP5	O75197-1.2	A98H	Neutral	0.014
LRP5	O75197-1.2	A98I	Neutral	0.001
LRP5	O75197-1.2	A98K	Neutral	0.002
LRP5	O75197-1.2	A98L	Neutral	0.002
LRP5	O75197-1.2	A98M	Neutral	0.002
LRP5	O75197-1.2	A98N	Neutral	0.008
LRP5	O75197-1.2	A98P	Neutral	0.004
LRP5	O75197-1.2	A98Q	Neutral	0.004
LRP5	O75197-1.2	A98R	Neutral	0.002
LRP5	O75197-1.2	A98S	Neutral	0.0
LRP5	O75197-1.2	A98T	Neutral	0.002
LRP5	O75197-1.2	A98V	Neutral	0.001
LRP5	O75197-1.2	A98W	Neutral	0.008
LRP5	O75197-1.2	A98Y	Neutral	0.009
LRP5	O75197-1.2	V99A	Neutral	0.007
LRP5	O75197-1.2	V99C	Neutral	0.039
LRP5	O75197-1.2	V99D	Neutral	0.073
LRP5	O75197-1.2	V99E	Neutral	0.029
LRP5	O75197-1.2	V99F	Neutral	0.028
LRP5	O75197-1.2	V99G	Neutral	0.127
LRP5	O75197-1.2	V99H	Neutral	0.149
LRP5	O75197-1.2	V99I	Neutral	0.0
LRP5	O75197-1.2	V99K	Neutral	0.02
LRP5	O75197-1.2	V99L	Neutral	0.003
LRP5	O75197-1.2	V99M	Neutral	0.005
LRP5	O75197-1.2	V99N	Neutral	0.084
LRP5	O75197-1.2	V99P	Neutral	0.089
LRP5	O75197-1.2	V99Q	Neutral	0.041
LRP5	O75197-1.2	V99R	Neutral	0.057
LRP5	O75197-1.2	V99S	Neutral	0.046
LRP5	O75197-1.2	V99T	Neutral	0.007
LRP5	O75197-1.2	V99W	Neutral	0.146
LRP5	O75197-1.2	V99Y	Neutral	0.037
LRP5	O75197-1.2	Q100A	Pathogenic	0.773
LRP5	O75197-1.2	Q100C	Pathogenic	0.947
LRP5	O75197-1.2	Q100D	Pathogenic	0.532
LRP5	O75197-1.2	Q100E	Neutral	0.125
LRP5	O75197-1.2	Q100F	Pathogenic	0.897
LRP5	O75197-1.2	Q100G	Pathogenic	0.93
LRP5	O75197-1.2	Q100H	Pathogenic	0.584
LRP5	O75197-1.2	Q100I	Pathogenic	0.898
LRP5	O75197-1.2	Q100K	Neutral	0.236
LRP5	O75197-1.2	Q100L	Pathogenic	0.76
LRP5	O75197-1.2	Q100M	Neutral	0.342
LRP5	O75197-1.2	Q100N	Pathogenic	0.572
LRP5	O75197-1.2	Q100P	Pathogenic	0.71
LRP5	O75197-1.2	Q100R	Neutral	0.23
LRP5	O75197-1.2	Q100S	Pathogenic	0.606
LRP5	O75197-1.2	Q100T	Pathogenic	0.788
LRP5	O75197-1.2	Q100V	Pathogenic	0.83
LRP5	O75197-1.2	Q100W	Pathogenic	0.645
LRP5	O75197-1.2	Q100Y	Pathogenic	0.662
LRP5	O75197-1.2	N101A	Neutral	0.199
LRP5	O75197-1.2	N101C	Neutral	0.299
LRP5	O75197-1.2	N101D	Neutral	0.017
LRP5	O75197-1.2	N101E	Neutral	0.057
LRP5	O75197-1.2	N101F	Neutral	0.165
LRP5	O75197-1.2	N101G	Neutral	0.033
LRP5	O75197-1.2	N101H	Neutral	0.01
LRP5	O75197-1.2	N101I	Neutral	0.166
LRP5	O75197-1.2	N101K	Neutral	0.04
LRP5	O75197-1.2	N101L	Neutral	0.179
LRP5	O75197-1.2	N101M	Neutral	0.098
LRP5	O75197-1.2	N101P	Neutral	0.151
LRP5	O75197-1.2	N101Q	Neutral	0.042
LRP5	O75197-1.2	N101R	Neutral	0.039
LRP5	O75197-1.2	N101S	Neutral	0.012
LRP5	O75197-1.2	N101T	Neutral	0.028
LRP5	O75197-1.2	N101V	Neutral	0.257
LRP5	O75197-1.2	N101W	Neutral	0.275
LRP5	O75197-1.2	N101Y	Neutral	0.119
LRP5	O75197-1.2	V102A	Neutral	0.414
LRP5	O75197-1.2	V102C	Pathogenic	0.802
LRP5	O75197-1.2	V102D	Pathogenic	0.887
LRP5	O75197-1.2	V102E	Pathogenic	0.747
LRP5	O75197-1.2	V102F	Pathogenic	0.746
LRP5	O75197-1.2	V102G	Pathogenic	0.936
LRP5	O75197-1.2	V102H	Pathogenic	0.946
LRP5	O75197-1.2	V102I	Neutral	0.033
LRP5	O75197-1.2	V102K	Pathogenic	0.675
LRP5	O75197-1.2	V102L	Neutral	0.259
LRP5	O75197-1.2	V102M	Neutral	0.347
LRP5	O75197-1.2	V102N	Pathogenic	0.902
LRP5	O75197-1.2	V102P	Pathogenic	0.907
LRP5	O75197-1.2	V102Q	Pathogenic	0.81
LRP5	O75197-1.2	V102R	Pathogenic	0.859
LRP5	O75197-1.2	V102S	Pathogenic	0.829
LRP5	O75197-1.2	V102T	Neutral	0.413
LRP5	O75197-1.2	V102W	Pathogenic	0.945
LRP5	O75197-1.2	V102Y	Pathogenic	0.794
LRP5	O75197-1.2	V103A	Neutral	0.358
LRP5	O75197-1.2	V103C	Pathogenic	0.762
LRP5	O75197-1.2	V103D	Pathogenic	0.862
LRP5	O75197-1.2	V103E	Pathogenic	0.701
LRP5	O75197-1.2	V103F	Pathogenic	0.699
LRP5	O75197-1.2	V103G	Pathogenic	0.92
LRP5	O75197-1.2	V103H	Pathogenic	0.933
LRP5	O75197-1.2	V103I	Neutral	0.027
LRP5	O75197-1.2	V103K	Pathogenic	0.621
LRP5	O75197-1.2	V103L	Neutral	0.217
LRP5	O75197-1.2	V103M	Neutral	0.296
LRP5	O75197-1.2	V103N	Pathogenic	0.88
LRP5	O75197-1.2	V103P	Pathogenic	0.886
LRP5	O75197-1.2	V103Q	Pathogenic	0.772
LRP5	O75197-1.2	V103R	Pathogenic	0.828
LRP5	O75197-1.2	V103S	Pathogenic	0.793
LRP5	O75197-1.2	V103T	Neutral	0.357
LRP5	O75197-1.2	V103W	Pathogenic	0.932
LRP5	O75197-1.2	V103Y	Pathogenic	0.753
LRP5	O75197-1.2	I104A	Neutral	0.024
LRP5	O75197-1.2	I104C	Neutral	0.044
LRP5	O75197-1.2	I104D	Neutral	0.082
LRP5	O75197-1.2	I104E	Neutral	0.094
LRP5	O75197-1.2	I104F	Neutral	0.031
LRP5	O75197-1.2	I104G	Neutral	0.336
LRP5	O75197-1.2	I104H	Neutral	0.173
LRP5	O75197-1.2	I104K	Neutral	0.071
LRP5	O75197-1.2	I104L	Neutral	0.003
LRP5	O75197-1.2	I104M	Neutral	0.007
LRP5	O75197-1.2	I104N	Neutral	0.095
LRP5	O75197-1.2	I104P	Neutral	0.253
LRP5	O75197-1.2	I104Q	Neutral	0.132
LRP5	O75197-1.2	I104R	Neutral	0.069
LRP5	O75197-1.2	I104S	Neutral	0.052
LRP5	O75197-1.2	I104T	Neutral	0.024
LRP5	O75197-1.2	I104V	Neutral	0.001
LRP5	O75197-1.2	I104W	Neutral	0.373
LRP5	O75197-1.2	I104Y	Neutral	0.045
LRP5	O75197-1.2	S105A	Neutral	0.103
LRP5	O75197-1.2	S105C	Neutral	0.366
LRP5	O75197-1.2	S105D	Neutral	0.195
LRP5	O75197-1.2	S105E	Neutral	0.21
LRP5	O75197-1.2	S105F	Neutral	0.441
LRP5	O75197-1.2	S105G	Neutral	0.309
LRP5	O75197-1.2	S105H	Pathogenic	0.54
LRP5	O75197-1.2	S105I	Neutral	0.442
LRP5	O75197-1.2	S105K	Neutral	0.157
LRP5	O75197-1.2	S105L	Neutral	0.465
LRP5	O75197-1.2	S105M	Neutral	0.303
LRP5	O75197-1.2	S105N	Neutral	0.084
LRP5	O75197-1.2	S105P	Neutral	0.421
LRP5	O75197-1.2	S105Q	Neutral	0.277
LRP5	O75197-1.2	S105R	Neutral	0.354
LRP5	O75197-1.2	S105T	Neutral	0.106
LRP5	O75197-1.2	S105V	Pathogenic	0.58
LRP5	O75197-1.2	S105W	Pathogenic	0.603
LRP5	O75197-1.2	S105Y	Pathogenic	0.621
LRP5	O75197-1.2	G106A	Pathogenic	0.568
LRP5	O75197-1.2	G106C	Pathogenic	0.952
LRP5	O75197-1.2	G106D	Pathogenic	0.718
LRP5	O75197-1.2	G106E	Pathogenic	0.894
LRP5	O75197-1.2	G106F	Pathogenic	0.898
LRP5	O75197-1.2	G106H	Pathogenic	0.929
LRP5	O75197-1.2	G106I	Pathogenic	0.964
LRP5	O75197-1.2	G106K	Pathogenic	0.856
LRP5	O75197-1.2	G106L	Pathogenic	0.967
LRP5	O75197-1.2	G106M	Pathogenic	0.937
LRP5	O75197-1.2	G106N	Neutral	0.491
LRP5	O75197-1.2	G106P	Pathogenic	0.89
LRP5	O75197-1.2	G106Q	Pathogenic	0.924
LRP5	O75197-1.2	G106R	Pathogenic	0.851
LRP5	O75197-1.2	G106S	Pathogenic	0.624
LRP5	O75197-1.2	G106T	Pathogenic	0.924
LRP5	O75197-1.2	G106V	Pathogenic	0.939
LRP5	O75197-1.2	G106W	Pathogenic	0.647
LRP5	O75197-1.2	G106Y	Pathogenic	0.948
LRP5	O75197-1.2	L107A	Pathogenic	0.764
LRP5	O75197-1.2	L107C	Pathogenic	0.859
LRP5	O75197-1.2	L107D	Pathogenic	0.973
LRP5	O75197-1.2	L107E	Pathogenic	0.932
LRP5	O75197-1.2	L107F	Pathogenic	0.787
LRP5	O75197-1.2	L107G	Pathogenic	0.985
LRP5	O75197-1.2	L107H	Pathogenic	0.965
LRP5	O75197-1.2	L107I	Neutral	0.286
LRP5	O75197-1.2	L107K	Pathogenic	0.769
LRP5	O75197-1.2	L107M	Neutral	0.224
LRP5	O75197-1.2	L107N	Pathogenic	0.933
LRP5	O75197-1.2	L107P	Pathogenic	0.978
LRP5	O75197-1.2	L107Q	Pathogenic	0.869
LRP5	O75197-1.2	L107R	Pathogenic	0.763
LRP5	O75197-1.2	L107S	Pathogenic	0.88
LRP5	O75197-1.2	L107T	Pathogenic	0.763
LRP5	O75197-1.2	L107V	Neutral	0.456
LRP5	O75197-1.2	L107W	Pathogenic	0.956
LRP5	O75197-1.2	L107Y	Pathogenic	0.861
LRP5	O75197-1.2	V108A	Neutral	0.012
LRP5	O75197-1.2	V108C	Neutral	0.064
LRP5	O75197-1.2	V108D	Neutral	0.117
LRP5	O75197-1.2	V108E	Neutral	0.048
LRP5	O75197-1.2	V108F	Neutral	0.047
LRP5	O75197-1.2	V108G	Neutral	0.198
LRP5	O75197-1.2	V108H	Neutral	0.229
LRP5	O75197-1.2	V108I	Neutral	0.001
LRP5	O75197-1.2	V108K	Neutral	0.034
LRP5	O75197-1.2	V108L	Neutral	0.006
LRP5	O75197-1.2	V108M	Neutral	0.009
LRP5	O75197-1.2	V108N	Neutral	0.135
LRP5	O75197-1.2	V108P	Neutral	0.141
LRP5	O75197-1.2	V108Q	Neutral	0.067
LRP5	O75197-1.2	V108R	Neutral	0.093
LRP5	O75197-1.2	V108S	Neutral	0.075
LRP5	O75197-1.2	V108T	Neutral	0.012
LRP5	O75197-1.2	V108W	Neutral	0.225
LRP5	O75197-1.2	V108Y	Neutral	0.061
LRP5	O75197-1.2	S109A	Neutral	0.382
LRP5	O75197-1.2	S109C	Pathogenic	0.756
LRP5	O75197-1.2	S109D	Pathogenic	0.566
LRP5	O75197-1.2	S109E	Pathogenic	0.587
LRP5	O75197-1.2	S109F	Pathogenic	0.809
LRP5	O75197-1.2	S109G	Pathogenic	0.706
LRP5	O75197-1.2	S109H	Pathogenic	0.863
LRP5	O75197-1.2	S109I	Pathogenic	0.809
LRP5	O75197-1.2	S109K	Neutral	0.499
LRP5	O75197-1.2	S109L	Pathogenic	0.823
LRP5	O75197-1.2	S109M	Pathogenic	0.699
LRP5	O75197-1.2	S109N	Neutral	0.33
LRP5	O75197-1.2	S109P	Pathogenic	0.795
LRP5	O75197-1.2	S109Q	Pathogenic	0.672
LRP5	O75197-1.2	S109R	Pathogenic	0.746
LRP5	O75197-1.2	S109T	Neutral	0.387
LRP5	O75197-1.2	S109V	Pathogenic	0.881
LRP5	O75197-1.2	S109W	Pathogenic	0.891
LRP5	O75197-1.2	S109Y	Pathogenic	0.898
LRP5	O75197-1.2	P110A	Pathogenic	0.924
LRP5	O75197-1.2	P110C	Pathogenic	0.992
LRP5	O75197-1.2	P110D	Pathogenic	0.827
LRP5	O75197-1.2	P110E	Pathogenic	0.84
LRP5	O75197-1.2	P110F	Pathogenic	0.995
LRP5	O75197-1.2	P110G	Pathogenic	0.964
LRP5	O75197-1.2	P110H	Pathogenic	0.969
LRP5	O75197-1.2	P110I	Pathogenic	0.984
LRP5	O75197-1.2	P110K	Pathogenic	0.786
LRP5	O75197-1.2	P110L	Pathogenic	0.985
LRP5	O75197-1.2	P110M	Pathogenic	0.971
LRP5	O75197-1.2	P110N	Pathogenic	0.944
LRP5	O75197-1.2	P110Q	Pathogenic	0.883
LRP5	O75197-1.2	P110R	Pathogenic	0.915
LRP5	O75197-1.2	P110S	Pathogenic	0.9
LRP5	O75197-1.2	P110T	Pathogenic	0.923
LRP5	O75197-1.2	P110V	Pathogenic	0.972
LRP5	O75197-1.2	P110W	Pathogenic	0.991
LRP5	O75197-1.2	P110Y	Pathogenic	0.992
LRP5	O75197-1.2	D111A	Pathogenic	0.896
LRP5	O75197-1.2	D111C	Pathogenic	0.937
LRP5	O75197-1.2	D111E	Neutral	0.192
LRP5	O75197-1.2	D111F	Pathogenic	0.871
LRP5	O75197-1.2	D111G	Pathogenic	0.784
LRP5	O75197-1.2	D111H	Pathogenic	0.768
LRP5	O75197-1.2	D111I	Pathogenic	0.872
LRP5	O75197-1.2	D111K	Pathogenic	0.856
LRP5	O75197-1.2	D111L	Pathogenic	0.958
LRP5	O75197-1.2	D111M	Pathogenic	0.919
LRP5	O75197-1.2	D111N	Neutral	0.417
LRP5	O75197-1.2	D111P	Pathogenic	0.671
LRP5	O75197-1.2	D111Q	Pathogenic	0.6
LRP5	O75197-1.2	D111R	Pathogenic	0.946
LRP5	O75197-1.2	D111S	Pathogenic	0.562
LRP5	O75197-1.2	D111T	Pathogenic	0.755
LRP5	O75197-1.2	D111V	Pathogenic	0.922
LRP5	O75197-1.2	D111W	Pathogenic	0.929
LRP5	O75197-1.2	D111Y	Pathogenic	0.934
LRP5	O75197-1.2	G112A	Pathogenic	0.827
LRP5	O75197-1.2	G112C	Pathogenic	0.986
LRP5	O75197-1.2	G112D	Pathogenic	0.902
LRP5	O75197-1.2	G112E	Pathogenic	0.969
LRP5	O75197-1.2	G112F	Pathogenic	0.97
LRP5	O75197-1.2	G112H	Pathogenic	0.979
LRP5	O75197-1.2	G112I	Pathogenic	0.99
LRP5	O75197-1.2	G112K	Pathogenic	0.956
LRP5	O75197-1.2	G112L	Pathogenic	0.991
LRP5	O75197-1.2	G112M	Pathogenic	0.982
LRP5	O75197-1.2	G112N	Pathogenic	0.778
LRP5	O75197-1.2	G112P	Pathogenic	0.967
LRP5	O75197-1.2	G112Q	Pathogenic	0.978
LRP5	O75197-1.2	G112R	Pathogenic	0.954
LRP5	O75197-1.2	G112S	Pathogenic	0.858
LRP5	O75197-1.2	G112T	Pathogenic	0.978
LRP5	O75197-1.2	G112V	Pathogenic	0.982
LRP5	O75197-1.2	G112W	Pathogenic	0.87
LRP5	O75197-1.2	G112Y	Pathogenic	0.985
LRP5	O75197-1.2	L113A	Pathogenic	0.775
LRP5	O75197-1.2	L113C	Pathogenic	0.867
LRP5	O75197-1.2	L113D	Pathogenic	0.975
LRP5	O75197-1.2	L113E	Pathogenic	0.936
LRP5	O75197-1.2	L113F	Pathogenic	0.797
LRP5	O75197-1.2	L113G	Pathogenic	0.986
LRP5	O75197-1.2	L113H	Pathogenic	0.967
LRP5	O75197-1.2	L113I	Neutral	0.299
LRP5	O75197-1.2	L113K	Pathogenic	0.78
LRP5	O75197-1.2	L113M	Neutral	0.235
LRP5	O75197-1.2	L113N	Pathogenic	0.937
LRP5	O75197-1.2	L113P	Pathogenic	0.98
LRP5	O75197-1.2	L113Q	Pathogenic	0.876
LRP5	O75197-1.2	L113R	Pathogenic	0.774
LRP5	O75197-1.2	L113S	Pathogenic	0.886
LRP5	O75197-1.2	L113T	Pathogenic	0.775
LRP5	O75197-1.2	L113V	Neutral	0.472
LRP5	O75197-1.2	L113W	Pathogenic	0.958
LRP5	O75197-1.2	L113Y	Pathogenic	0.868
LRP5	O75197-1.2	A114C	Pathogenic	0.794
LRP5	O75197-1.2	A114D	Pathogenic	0.961
LRP5	O75197-1.2	A114E	Pathogenic	0.898
LRP5	O75197-1.2	A114F	Pathogenic	0.941
LRP5	O75197-1.2	A114G	Pathogenic	0.842
LRP5	O75197-1.2	A114H	Pathogenic	0.981
LRP5	O75197-1.2	A114I	Pathogenic	0.841
LRP5	O75197-1.2	A114K	Pathogenic	0.861
LRP5	O75197-1.2	A114L	Pathogenic	0.853
LRP5	O75197-1.2	A114M	Pathogenic	0.898
LRP5	O75197-1.2	A114N	Pathogenic	0.966
LRP5	O75197-1.2	A114P	Pathogenic	0.936
LRP5	O75197-1.2	A114Q	Pathogenic	0.927
LRP5	O75197-1.2	A114R	Pathogenic	0.857
LRP5	O75197-1.2	A114S	Pathogenic	0.634
LRP5	O75197-1.2	A114T	Pathogenic	0.869
LRP5	O75197-1.2	A114V	Pathogenic	0.751
LRP5	O75197-1.2	A114W	Pathogenic	0.969
LRP5	O75197-1.2	A114Y	Pathogenic	0.971
LRP5	O75197-1.2	C115A	Pathogenic	0.774
LRP5	O75197-1.2	C115D	Pathogenic	0.974
LRP5	O75197-1.2	C115E	Pathogenic	0.992
LRP5	O75197-1.2	C115F	Pathogenic	0.964
LRP5	O75197-1.2	C115G	Pathogenic	0.986
LRP5	O75197-1.2	C115H	Pathogenic	0.988
LRP5	O75197-1.2	C115I	Pathogenic	0.899
LRP5	O75197-1.2	C115K	Pathogenic	0.966
LRP5	O75197-1.2	C115L	Pathogenic	0.907
LRP5	O75197-1.2	C115M	Pathogenic	0.937
LRP5	O75197-1.2	C115N	Pathogenic	0.977
LRP5	O75197-1.2	C115P	Pathogenic	0.993
LRP5	O75197-1.2	C115Q	Pathogenic	0.983
LRP5	O75197-1.2	C115R	Pathogenic	0.965
LRP5	O75197-1.2	C115S	Pathogenic	0.886
LRP5	O75197-1.2	C115T	Pathogenic	0.91
LRP5	O75197-1.2	C115V	Pathogenic	0.939
LRP5	O75197-1.2	C115W	Pathogenic	0.944
LRP5	O75197-1.2	C115Y	Pathogenic	0.982
LRP5	O75197-1.2	D116A	Pathogenic	0.946
LRP5	O75197-1.2	D116C	Pathogenic	0.968
LRP5	O75197-1.2	D116E	Neutral	0.323
LRP5	O75197-1.2	D116F	Pathogenic	0.932
LRP5	O75197-1.2	D116G	Pathogenic	0.88
LRP5	O75197-1.2	D116H	Pathogenic	0.869
LRP5	O75197-1.2	D116I	Pathogenic	0.932
LRP5	O75197-1.2	D116K	Pathogenic	0.923
LRP5	O75197-1.2	D116L	Pathogenic	0.979
LRP5	O75197-1.2	D116M	Pathogenic	0.958
LRP5	O75197-1.2	D116N	Pathogenic	0.589
LRP5	O75197-1.2	D116P	Pathogenic	0.804
LRP5	O75197-1.2	D116Q	Pathogenic	0.751
LRP5	O75197-1.2	D116R	Pathogenic	0.972
LRP5	O75197-1.2	D116S	Pathogenic	0.721
LRP5	O75197-1.2	D116T	Pathogenic	0.861
LRP5	O75197-1.2	D116V	Pathogenic	0.96
LRP5	O75197-1.2	D116W	Pathogenic	0.963
LRP5	O75197-1.2	D116Y	Pathogenic	0.966
LRP5	O75197-1.2	W117A	Pathogenic	0.991
LRP5	O75197-1.2	W117C	Pathogenic	0.986
LRP5	O75197-1.2	W117D	Pathogenic	0.993
LRP5	O75197-1.2	W117E	Pathogenic	0.982
LRP5	O75197-1.2	W117F	Pathogenic	0.85
LRP5	O75197-1.2	W117G	Pathogenic	0.966
LRP5	O75197-1.2	W117H	Pathogenic	0.972
LRP5	O75197-1.2	W117I	Pathogenic	0.998
LRP5	O75197-1.2	W117K	Pathogenic	0.976
LRP5	O75197-1.2	W117L	Pathogenic	0.993
LRP5	O75197-1.2	W117M	Pathogenic	0.969
LRP5	O75197-1.2	W117N	Pathogenic	0.994
LRP5	O75197-1.2	W117P	Pathogenic	0.998
LRP5	O75197-1.2	W117Q	Pathogenic	0.962
LRP5	O75197-1.2	W117R	Pathogenic	0.976
LRP5	O75197-1.2	W117S	Pathogenic	0.989
LRP5	O75197-1.2	W117T	Pathogenic	0.974
LRP5	O75197-1.2	W117V	Pathogenic	0.996
LRP5	O75197-1.2	W117Y	Neutral	0.473
LRP5	O75197-1.2	V118A	Neutral	0.008
LRP5	O75197-1.2	V118C	Neutral	0.042
LRP5	O75197-1.2	V118D	Neutral	0.079
LRP5	O75197-1.2	V118E	Neutral	0.031
LRP5	O75197-1.2	V118F	Neutral	0.031
LRP5	O75197-1.2	V118G	Neutral	0.137
LRP5	O75197-1.2	V118H	Neutral	0.161
LRP5	O75197-1.2	V118I	Neutral	0.0
LRP5	O75197-1.2	V118K	Neutral	0.022
LRP5	O75197-1.2	V118L	Neutral	0.004
LRP5	O75197-1.2	V118M	Neutral	0.006
LRP5	O75197-1.2	V118N	Neutral	0.091
LRP5	O75197-1.2	V118P	Neutral	0.096
LRP5	O75197-1.2	V118Q	Neutral	0.044
LRP5	O75197-1.2	V118R	Neutral	0.062
LRP5	O75197-1.2	V118S	Neutral	0.05
LRP5	O75197-1.2	V118T	Neutral	0.008
LRP5	O75197-1.2	V118W	Neutral	0.157
LRP5	O75197-1.2	V118Y	Neutral	0.04
LRP5	O75197-1.2	G119A	Neutral	0.416
LRP5	O75197-1.2	G119C	Pathogenic	0.914
LRP5	O75197-1.2	G119D	Pathogenic	0.58
LRP5	O75197-1.2	G119E	Pathogenic	0.821
LRP5	O75197-1.2	G119F	Pathogenic	0.827
LRP5	O75197-1.2	G119H	Pathogenic	0.877
LRP5	O75197-1.2	G119I	Pathogenic	0.936
LRP5	O75197-1.2	G119K	Pathogenic	0.763
LRP5	O75197-1.2	G119L	Pathogenic	0.941
LRP5	O75197-1.2	G119M	Pathogenic	0.889
LRP5	O75197-1.2	G119N	Neutral	0.344
LRP5	O75197-1.2	G119P	Pathogenic	0.815
LRP5	O75197-1.2	G119Q	Pathogenic	0.869
LRP5	O75197-1.2	G119R	Pathogenic	0.757
LRP5	O75197-1.2	G119S	Neutral	0.474
LRP5	O75197-1.2	G119T	Pathogenic	0.869
LRP5	O75197-1.2	G119V	Pathogenic	0.893
LRP5	O75197-1.2	G119W	Neutral	0.499
LRP5	O75197-1.2	G119Y	Pathogenic	0.909
LRP5	O75197-1.2	K120A	Neutral	0.027
LRP5	O75197-1.2	K120C	Neutral	0.126
LRP5	O75197-1.2	K120D	Neutral	0.07
LRP5	O75197-1.2	K120E	Neutral	0.007
LRP5	O75197-1.2	K120F	Neutral	0.071
LRP5	O75197-1.2	K120G	Neutral	0.097
LRP5	O75197-1.2	K120H	Neutral	0.034
LRP5	O75197-1.2	K120I	Neutral	0.069
LRP5	O75197-1.2	K120L	Neutral	0.026
LRP5	O75197-1.2	K120M	Neutral	0.013
LRP5	O75197-1.2	K120N	Neutral	0.021
LRP5	O75197-1.2	K120P	Neutral	0.019
LRP5	O75197-1.2	K120Q	Neutral	0.005
LRP5	O75197-1.2	K120R	Neutral	0.003
LRP5	O75197-1.2	K120S	Neutral	0.012
LRP5	O75197-1.2	K120T	Neutral	0.029
LRP5	O75197-1.2	K120V	Neutral	0.038
LRP5	O75197-1.2	K120W	Neutral	0.046
LRP5	O75197-1.2	K120Y	Neutral	0.049
LRP5	O75197-1.2	K121A	Pathogenic	0.922
LRP5	O75197-1.2	K121C	Pathogenic	0.984
LRP5	O75197-1.2	K121D	Pathogenic	0.97
LRP5	O75197-1.2	K121E	Pathogenic	0.762
LRP5	O75197-1.2	K121F	Pathogenic	0.97
LRP5	O75197-1.2	K121G	Pathogenic	0.979
LRP5	O75197-1.2	K121H	Pathogenic	0.938
LRP5	O75197-1.2	K121I	Pathogenic	0.969
LRP5	O75197-1.2	K121L	Pathogenic	0.919
LRP5	O75197-1.2	K121M	Pathogenic	0.851
LRP5	O75197-1.2	K121N	Pathogenic	0.902
LRP5	O75197-1.2	K121P	Pathogenic	0.895
LRP5	O75197-1.2	K121Q	Pathogenic	0.69
LRP5	O75197-1.2	K121R	Pathogenic	0.593
LRP5	O75197-1.2	K121S	Pathogenic	0.843
LRP5	O75197-1.2	K121T	Pathogenic	0.929
LRP5	O75197-1.2	K121V	Pathogenic	0.945
LRP5	O75197-1.2	K121W	Pathogenic	0.954
LRP5	O75197-1.2	K121Y	Pathogenic	0.957
LRP5	O75197-1.2	L122A	Pathogenic	0.802
LRP5	O75197-1.2	L122C	Pathogenic	0.884
LRP5	O75197-1.2	L122D	Pathogenic	0.978
LRP5	O75197-1.2	L122E	Pathogenic	0.945
LRP5	O75197-1.2	L122F	Pathogenic	0.821
LRP5	O75197-1.2	L122G	Pathogenic	0.988
LRP5	O75197-1.2	L122H	Pathogenic	0.972
LRP5	O75197-1.2	L122I	Neutral	0.333
LRP5	O75197-1.2	L122K	Pathogenic	0.806
LRP5	O75197-1.2	L122M	Neutral	0.264
LRP5	O75197-1.2	L122N	Pathogenic	0.946
LRP5	O75197-1.2	L122P	Pathogenic	0.982
LRP5	O75197-1.2	L122Q	Pathogenic	0.892
LRP5	O75197-1.2	L122R	Pathogenic	0.8
LRP5	O75197-1.2	L122S	Pathogenic	0.901
LRP5	O75197-1.2	L122T	Pathogenic	0.801
LRP5	O75197-1.2	L122V	Pathogenic	0.512
LRP5	O75197-1.2	L122W	Pathogenic	0.964
LRP5	O75197-1.2	L122Y	Pathogenic	0.885
LRP5	O75197-1.2	Y123A	Pathogenic	0.983
LRP5	O75197-1.2	Y123C	Pathogenic	0.991
LRP5	O75197-1.2	Y123D	Pathogenic	0.986
LRP5	O75197-1.2	Y123E	Pathogenic	0.964
LRP5	O75197-1.2	Y123F	Neutral	0.178
LRP5	O75197-1.2	Y123G	Pathogenic	0.993
LRP5	O75197-1.2	Y123H	Neutral	0.39
LRP5	O75197-1.2	Y123I	Pathogenic	0.947
LRP5	O75197-1.2	Y123K	Pathogenic	0.954
LRP5	O75197-1.2	Y123L	Pathogenic	0.952
LRP5	O75197-1.2	Y123M	Pathogenic	0.968
LRP5	O75197-1.2	Y123N	Pathogenic	0.965
LRP5	O75197-1.2	Y123P	Pathogenic	0.996
LRP5	O75197-1.2	Y123Q	Pathogenic	0.929
LRP5	O75197-1.2	Y123R	Pathogenic	0.953
LRP5	O75197-1.2	Y123S	Pathogenic	0.978
LRP5	O75197-1.2	Y123T	Pathogenic	0.983
LRP5	O75197-1.2	Y123V	Pathogenic	0.967
LRP5	O75197-1.2	Y123W	Neutral	0.298
LRP5	O75197-1.2	W124A	Pathogenic	0.992
LRP5	O75197-1.2	W124C	Pathogenic	0.987
LRP5	O75197-1.2	W124D	Pathogenic	0.993
LRP5	O75197-1.2	W124E	Pathogenic	0.982
LRP5	O75197-1.2	W124F	Pathogenic	0.853
LRP5	O75197-1.2	W124G	Pathogenic	0.966
LRP5	O75197-1.2	W124H	Pathogenic	0.973
LRP5	O75197-1.2	W124I	Pathogenic	0.998
LRP5	O75197-1.2	W124K	Pathogenic	0.976
LRP5	O75197-1.2	W124L	Pathogenic	0.993
LRP5	O75197-1.2	W124M	Pathogenic	0.97
LRP5	O75197-1.2	W124N	Pathogenic	0.994
LRP5	O75197-1.2	W124P	Pathogenic	0.998
LRP5	O75197-1.2	W124Q	Pathogenic	0.963
LRP5	O75197-1.2	W124R	Pathogenic	0.977
LRP5	O75197-1.2	W124S	Pathogenic	0.989
LRP5	O75197-1.2	W124T	Pathogenic	0.975
LRP5	O75197-1.2	W124V	Pathogenic	0.996
LRP5	O75197-1.2	W124Y	Neutral	0.479
LRP5	O75197-1.2	T125A	Pathogenic	0.835
LRP5	O75197-1.2	T125C	Pathogenic	0.897
LRP5	O75197-1.2	T125D	Pathogenic	0.87
LRP5	O75197-1.2	T125E	Pathogenic	0.881
LRP5	O75197-1.2	T125F	Pathogenic	0.924
LRP5	O75197-1.2	T125G	Pathogenic	0.974
LRP5	O75197-1.2	T125H	Pathogenic	0.978
LRP5	O75197-1.2	T125I	Pathogenic	0.801
LRP5	O75197-1.2	T125K	Pathogenic	0.838
LRP5	O75197-1.2	T125L	Pathogenic	0.815
LRP5	O75197-1.2	T125M	Pathogenic	0.87
LRP5	O75197-1.2	T125N	Pathogenic	0.719
LRP5	O75197-1.2	T125P	Pathogenic	0.917
LRP5	O75197-1.2	T125Q	Pathogenic	0.914
LRP5	O75197-1.2	T125R	Pathogenic	0.833
LRP5	O75197-1.2	T125S	Pathogenic	0.576
LRP5	O75197-1.2	T125V	Pathogenic	0.697
LRP5	O75197-1.2	T125W	Pathogenic	0.885
LRP5	O75197-1.2	T125Y	Pathogenic	0.962
LRP5	O75197-1.2	D126A	Pathogenic	0.948
LRP5	O75197-1.2	D126C	Pathogenic	0.969
LRP5	O75197-1.2	D126E	Neutral	0.333
LRP5	O75197-1.2	D126F	Pathogenic	0.934
LRP5	O75197-1.2	D126G	Pathogenic	0.884
LRP5	O75197-1.2	D126H	Pathogenic	0.874
LRP5	O75197-1.2	D126I	Pathogenic	0.935
LRP5	O75197-1.2	D126K	Pathogenic	0.926
LRP5	O75197-1.2	D126L	Pathogenic	0.979
LRP5	O75197-1.2	D126M	Pathogenic	0.96
LRP5	O75197-1.2	D126N	Pathogenic	0.6
LRP5	O75197-1.2	D126P	Pathogenic	0.811
LRP5	O75197-1.2	D126Q	Pathogenic	0.759
LRP5	O75197-1.2	D126R	Pathogenic	0.973
LRP5	O75197-1.2	D126S	Pathogenic	0.729
LRP5	O75197-1.2	D126T	Pathogenic	0.866
LRP5	O75197-1.2	D126V	Pathogenic	0.961
LRP5	O75197-1.2	D126W	Pathogenic	0.965
LRP5	O75197-1.2	D126Y	Pathogenic	0.967
LRP5	O75197-1.2	S127A	Neutral	0.271
LRP5	O75197-1.2	S127C	Pathogenic	0.65
LRP5	O75197-1.2	S127D	Neutral	0.439
LRP5	O75197-1.2	S127E	Neutral	0.461
LRP5	O75197-1.2	S127F	Pathogenic	0.718
LRP5	O75197-1.2	S127G	Pathogenic	0.591
LRP5	O75197-1.2	S127H	Pathogenic	0.791
LRP5	O75197-1.2	S127I	Pathogenic	0.719
LRP5	O75197-1.2	S127K	Neutral	0.375
LRP5	O75197-1.2	S127L	Pathogenic	0.737
LRP5	O75197-1.2	S127M	Pathogenic	0.583
LRP5	O75197-1.2	S127N	Neutral	0.229
LRP5	O75197-1.2	S127P	Pathogenic	0.7
LRP5	O75197-1.2	S127Q	Pathogenic	0.552
LRP5	O75197-1.2	S127R	Pathogenic	0.638
LRP5	O75197-1.2	S127T	Neutral	0.275
LRP5	O75197-1.2	S127V	Pathogenic	0.816
LRP5	O75197-1.2	S127W	Pathogenic	0.83
LRP5	O75197-1.2	S127Y	Pathogenic	0.841
LRP5	O75197-1.2	E128A	Pathogenic	0.901
LRP5	O75197-1.2	E128C	Pathogenic	0.993
LRP5	O75197-1.2	E128D	Neutral	0.409
LRP5	O75197-1.2	E128F	Pathogenic	0.958
LRP5	O75197-1.2	E128G	Pathogenic	0.972
LRP5	O75197-1.2	E128H	Pathogenic	0.786
LRP5	O75197-1.2	E128I	Pathogenic	0.958
LRP5	O75197-1.2	E128K	Pathogenic	0.631
LRP5	O75197-1.2	E128L	Pathogenic	0.962
LRP5	O75197-1.2	E128M	Pathogenic	0.927
LRP5	O75197-1.2	E128N	Pathogenic	0.876
LRP5	O75197-1.2	E128P	Pathogenic	0.867
LRP5	O75197-1.2	E128Q	Neutral	0.354
LRP5	O75197-1.2	E128R	Pathogenic	0.834
LRP5	O75197-1.2	E128S	Pathogenic	0.804
LRP5	O75197-1.2	E128T	Pathogenic	0.908
LRP5	O75197-1.2	E128V	Pathogenic	0.929
LRP5	O75197-1.2	E128W	Pathogenic	0.935
LRP5	O75197-1.2	E128Y	Pathogenic	0.94
LRP5	O75197-1.2	T129A	Pathogenic	0.609
LRP5	O75197-1.2	T129C	Pathogenic	0.727
LRP5	O75197-1.2	T129D	Pathogenic	0.673
LRP5	O75197-1.2	T129E	Pathogenic	0.693
LRP5	O75197-1.2	T129F	Pathogenic	0.789
LRP5	O75197-1.2	T129G	Pathogenic	0.921
LRP5	O75197-1.2	T129H	Pathogenic	0.931
LRP5	O75197-1.2	T129I	Pathogenic	0.552
LRP5	O75197-1.2	T129K	Pathogenic	0.613
LRP5	O75197-1.2	T129L	Pathogenic	0.574
LRP5	O75197-1.2	T129M	Pathogenic	0.673
LRP5	O75197-1.2	T129N	Neutral	0.44
LRP5	O75197-1.2	T129P	Pathogenic	0.773
LRP5	O75197-1.2	T129Q	Pathogenic	0.765
LRP5	O75197-1.2	T129R	Pathogenic	0.605
LRP5	O75197-1.2	T129S	Neutral	0.294
LRP5	O75197-1.2	T129V	Neutral	0.414
LRP5	O75197-1.2	T129W	Pathogenic	0.702
LRP5	O75197-1.2	T129Y	Pathogenic	0.886
LRP5	O75197-1.2	N130A	Pathogenic	0.978
LRP5	O75197-1.2	N130C	Pathogenic	0.987
LRP5	O75197-1.2	N130D	Pathogenic	0.757
LRP5	O75197-1.2	N130E	Pathogenic	0.913
LRP5	O75197-1.2	N130F	Pathogenic	0.972
LRP5	O75197-1.2	N130G	Pathogenic	0.857
LRP5	O75197-1.2	N130H	Pathogenic	0.647
LRP5	O75197-1.2	N130I	Pathogenic	0.972
LRP5	O75197-1.2	N130K	Pathogenic	0.881
LRP5	O75197-1.2	N130L	Pathogenic	0.974
LRP5	O75197-1.2	N130M	Pathogenic	0.95
LRP5	O75197-1.2	N130P	Pathogenic	0.969
LRP5	O75197-1.2	N130Q	Pathogenic	0.885
LRP5	O75197-1.2	N130R	Pathogenic	0.877
LRP5	O75197-1.2	N130S	Pathogenic	0.68
LRP5	O75197-1.2	N130T	Pathogenic	0.837
LRP5	O75197-1.2	N130V	Pathogenic	0.984
LRP5	O75197-1.2	N130W	Pathogenic	0.985
LRP5	O75197-1.2	N130Y	Pathogenic	0.959
LRP5	O75197-1.2	R131A	Pathogenic	0.817
LRP5	O75197-1.2	R131C	Pathogenic	0.959
LRP5	O75197-1.2	R131D	Pathogenic	0.974
LRP5	O75197-1.2	R131E	Pathogenic	0.785
LRP5	O75197-1.2	R131F	Pathogenic	0.924
LRP5	O75197-1.2	R131G	Pathogenic	0.945
LRP5	O75197-1.2	R131H	Pathogenic	0.65
LRP5	O75197-1.2	R131I	Pathogenic	0.922
LRP5	O75197-1.2	R131K	Neutral	0.36
LRP5	O75197-1.2	R131L	Pathogenic	0.81
LRP5	O75197-1.2	R131M	Pathogenic	0.681
LRP5	O75197-1.2	R131N	Pathogenic	0.776
LRP5	O75197-1.2	R131P	Pathogenic	0.907
LRP5	O75197-1.2	R131Q	Neutral	0.454
LRP5	O75197-1.2	R131S	Pathogenic	0.86
LRP5	O75197-1.2	R131T	Pathogenic	0.829
LRP5	O75197-1.2	R131V	Pathogenic	0.951
LRP5	O75197-1.2	R131W	Pathogenic	0.89
LRP5	O75197-1.2	R131Y	Pathogenic	0.895
LRP5	O75197-1.2	I132A	Pathogenic	0.786
LRP5	O75197-1.2	I132C	Pathogenic	0.874
LRP5	O75197-1.2	I132D	Pathogenic	0.931
LRP5	O75197-1.2	I132E	Pathogenic	0.94
LRP5	O75197-1.2	I132F	Pathogenic	0.83
LRP5	O75197-1.2	I132G	Pathogenic	0.987
LRP5	O75197-1.2	I132H	Pathogenic	0.969
LRP5	O75197-1.2	I132K	Pathogenic	0.92
LRP5	O75197-1.2	I132L	Neutral	0.332
LRP5	O75197-1.2	I132M	Neutral	0.498
LRP5	O75197-1.2	I132N	Pathogenic	0.94
LRP5	O75197-1.2	I132P	Pathogenic	0.981
LRP5	O75197-1.2	I132Q	Pathogenic	0.958
LRP5	O75197-1.2	I132R	Pathogenic	0.917
LRP5	O75197-1.2	I132S	Pathogenic	0.892
LRP5	O75197-1.2	I132T	Pathogenic	0.785
LRP5	O75197-1.2	I132V	Neutral	0.093
LRP5	O75197-1.2	I132W	Pathogenic	0.989
LRP5	O75197-1.2	I132Y	Pathogenic	0.875
LRP5	O75197-1.2	E133A	Pathogenic	0.917
LRP5	O75197-1.2	E133C	Pathogenic	0.994
LRP5	O75197-1.2	E133D	Neutral	0.458
LRP5	O75197-1.2	E133F	Pathogenic	0.965
LRP5	O75197-1.2	E133G	Pathogenic	0.977
LRP5	O75197-1.2	E133H	Pathogenic	0.817
LRP5	O75197-1.2	E133I	Pathogenic	0.966
LRP5	O75197-1.2	E133K	Pathogenic	0.675
LRP5	O75197-1.2	E133L	Pathogenic	0.968
LRP5	O75197-1.2	E133M	Pathogenic	0.939
LRP5	O75197-1.2	E133N	Pathogenic	0.895
LRP5	O75197-1.2	E133P	Pathogenic	0.888
LRP5	O75197-1.2	E133Q	Neutral	0.4
LRP5	O75197-1.2	E133R	Pathogenic	0.86
LRP5	O75197-1.2	E133S	Pathogenic	0.833
LRP5	O75197-1.2	E133T	Pathogenic	0.923
LRP5	O75197-1.2	E133V	Pathogenic	0.941
LRP5	O75197-1.2	E133W	Pathogenic	0.946
LRP5	O75197-1.2	E133Y	Pathogenic	0.95
LRP5	O75197-1.2	V134A	Pathogenic	0.685
LRP5	O75197-1.2	V134C	Pathogenic	0.926
LRP5	O75197-1.2	V134D	Pathogenic	0.96
LRP5	O75197-1.2	V134E	Pathogenic	0.901
LRP5	O75197-1.2	V134F	Pathogenic	0.901
LRP5	O75197-1.2	V134G	Pathogenic	0.978
LRP5	O75197-1.2	V134H	Pathogenic	0.982
LRP5	O75197-1.2	V134I	Neutral	0.096
LRP5	O75197-1.2	V134K	Pathogenic	0.865
LRP5	O75197-1.2	V134L	Pathogenic	0.519
LRP5	O75197-1.2	V134M	Pathogenic	0.621
LRP5	O75197-1.2	V134N	Pathogenic	0.966
LRP5	O75197-1.2	V134P	Pathogenic	0.968
LRP5	O75197-1.2	V134Q	Pathogenic	0.929
LRP5	O75197-1.2	V134R	Pathogenic	0.949
LRP5	O75197-1.2	V134S	Pathogenic	0.937
LRP5	O75197-1.2	V134T	Pathogenic	0.684
LRP5	O75197-1.2	V134W	Pathogenic	0.981
LRP5	O75197-1.2	V134Y	Pathogenic	0.922
LRP5	O75197-1.2	A135C	Neutral	0.092
LRP5	O75197-1.2	A135D	Neutral	0.394
LRP5	O75197-1.2	A135E	Neutral	0.189
LRP5	O75197-1.2	A135F	Neutral	0.297
LRP5	O75197-1.2	A135G	Neutral	0.124
LRP5	O75197-1.2	A135H	Pathogenic	0.582
LRP5	O75197-1.2	A135I	Neutral	0.122
LRP5	O75197-1.2	A135K	Neutral	0.141
LRP5	O75197-1.2	A135L	Neutral	0.133
LRP5	O75197-1.2	A135M	Neutral	0.189
LRP5	O75197-1.2	A135N	Neutral	0.429
LRP5	O75197-1.2	A135P	Neutral	0.28
LRP5	O75197-1.2	A135Q	Neutral	0.252
LRP5	O75197-1.2	A135R	Neutral	0.137
LRP5	O75197-1.2	A135S	Neutral	0.044
LRP5	O75197-1.2	A135T	Neutral	0.149
LRP5	O75197-1.2	A135V	Neutral	0.074
LRP5	O75197-1.2	A135W	Neutral	0.448
LRP5	O75197-1.2	A135Y	Neutral	0.467
LRP5	O75197-1.2	N136A	Pathogenic	0.601
LRP5	O75197-1.2	N136C	Pathogenic	0.721
LRP5	O75197-1.2	N136D	Neutral	0.097
LRP5	O75197-1.2	N136E	Neutral	0.267
LRP5	O75197-1.2	N136F	Pathogenic	0.545
LRP5	O75197-1.2	N136G	Neutral	0.172
LRP5	O75197-1.2	N136H	Neutral	0.06
LRP5	O75197-1.2	N136I	Pathogenic	0.546
LRP5	O75197-1.2	N136K	Neutral	0.203
LRP5	O75197-1.2	N136L	Pathogenic	0.569
LRP5	O75197-1.2	N136M	Neutral	0.398
LRP5	O75197-1.2	N136P	Pathogenic	0.52
LRP5	O75197-1.2	N136Q	Neutral	0.21
LRP5	O75197-1.2	N136R	Neutral	0.198
LRP5	O75197-1.2	N136S	Neutral	0.068
LRP5	O75197-1.2	N136T	Neutral	0.151
LRP5	O75197-1.2	N136V	Pathogenic	0.677
LRP5	O75197-1.2	N136W	Pathogenic	0.698
LRP5	O75197-1.2	N136Y	Neutral	0.45
LRP5	O75197-1.2	L137A	Neutral	0.369
LRP5	O75197-1.2	L137C	Pathogenic	0.525
LRP5	O75197-1.2	L137D	Pathogenic	0.867
LRP5	O75197-1.2	L137E	Pathogenic	0.714
LRP5	O75197-1.2	L137F	Neutral	0.4
LRP5	O75197-1.2	L137G	Pathogenic	0.924
LRP5	O75197-1.2	L137H	Pathogenic	0.834
LRP5	O75197-1.2	L137I	Neutral	0.067
LRP5	O75197-1.2	L137K	Neutral	0.376
LRP5	O75197-1.2	L137M	Neutral	0.05
LRP5	O75197-1.2	L137N	Pathogenic	0.716
LRP5	O75197-1.2	L137P	Pathogenic	0.89
LRP5	O75197-1.2	L137Q	Pathogenic	0.545
LRP5	O75197-1.2	L137R	Neutral	0.368
LRP5	O75197-1.2	L137S	Pathogenic	0.569
LRP5	O75197-1.2	L137T	Neutral	0.369
LRP5	O75197-1.2	L137V	Neutral	0.132
LRP5	O75197-1.2	L137W	Pathogenic	0.796
LRP5	O75197-1.2	L137Y	Pathogenic	0.528
LRP5	O75197-1.2	N138A	Pathogenic	0.567
LRP5	O75197-1.2	N138C	Pathogenic	0.692
LRP5	O75197-1.2	N138D	Neutral	0.086
LRP5	O75197-1.2	N138E	Neutral	0.24
LRP5	O75197-1.2	N138F	Pathogenic	0.51
LRP5	O75197-1.2	N138G	Neutral	0.153
LRP5	O75197-1.2	N138H	Neutral	0.052
LRP5	O75197-1.2	N138I	Pathogenic	0.511
LRP5	O75197-1.2	N138K	Neutral	0.181
LRP5	O75197-1.2	N138L	Pathogenic	0.534
LRP5	O75197-1.2	N138M	Neutral	0.364
LRP5	O75197-1.2	N138P	Neutral	0.485
LRP5	O75197-1.2	N138Q	Neutral	0.187
LRP5	O75197-1.2	N138R	Neutral	0.176
LRP5	O75197-1.2	N138S	Neutral	0.06
LRP5	O75197-1.2	N138T	Neutral	0.134
LRP5	O75197-1.2	N138V	Pathogenic	0.646
LRP5	O75197-1.2	N138W	Pathogenic	0.667
LRP5	O75197-1.2	N138Y	Neutral	0.416
LRP5	O75197-1.2	G139A	Pathogenic	0.814
LRP5	O75197-1.2	G139C	Pathogenic	0.985
LRP5	O75197-1.2	G139D	Pathogenic	0.894
LRP5	O75197-1.2	G139E	Pathogenic	0.966
LRP5	O75197-1.2	G139F	Pathogenic	0.967
LRP5	O75197-1.2	G139H	Pathogenic	0.978
LRP5	O75197-1.2	G139I	Pathogenic	0.989
LRP5	O75197-1.2	G139K	Pathogenic	0.952
LRP5	O75197-1.2	G139L	Pathogenic	0.99
LRP5	O75197-1.2	G139M	Pathogenic	0.98
LRP5	O75197-1.2	G139N	Pathogenic	0.762
LRP5	O75197-1.2	G139P	Pathogenic	0.964
LRP5	O75197-1.2	G139Q	Pathogenic	0.976
LRP5	O75197-1.2	G139R	Pathogenic	0.95
LRP5	O75197-1.2	G139S	Pathogenic	0.847
LRP5	O75197-1.2	G139T	Pathogenic	0.976
LRP5	O75197-1.2	G139V	Pathogenic	0.981
LRP5	O75197-1.2	G139W	Pathogenic	0.859
LRP5	O75197-1.2	G139Y	Pathogenic	0.984
LRP5	O75197-1.2	T140A	Neutral	0.056
LRP5	O75197-1.2	T140C	Neutral	0.092
LRP5	O75197-1.2	T140D	Neutral	0.072
LRP5	O75197-1.2	T140E	Neutral	0.079
LRP5	O75197-1.2	T140F	Neutral	0.124
LRP5	O75197-1.2	T140G	Neutral	0.306
LRP5	O75197-1.2	T140H	Neutral	0.339
LRP5	O75197-1.2	T140I	Neutral	0.045
LRP5	O75197-1.2	T140K	Neutral	0.057
LRP5	O75197-1.2	T140L	Neutral	0.049
LRP5	O75197-1.2	T140M	Neutral	0.072
LRP5	O75197-1.2	T140N	Neutral	0.029
LRP5	O75197-1.2	T140P	Neutral	0.114
LRP5	O75197-1.2	T140Q	Neutral	0.11
LRP5	O75197-1.2	T140R	Neutral	0.055
LRP5	O75197-1.2	T140S	Neutral	0.016
LRP5	O75197-1.2	T140V	Neutral	0.026
LRP5	O75197-1.2	T140W	Neutral	0.082
LRP5	O75197-1.2	T140Y	Neutral	0.228
LRP5	O75197-1.2	S141A	Neutral	0.004
LRP5	O75197-1.2	S141C	Neutral	0.02
LRP5	O75197-1.2	S141D	Neutral	0.009
LRP5	O75197-1.2	S141E	Neutral	0.009
LRP5	O75197-1.2	S141F	Neutral	0.027
LRP5	O75197-1.2	S141G	Neutral	0.016
LRP5	O75197-1.2	S141H	Neutral	0.04
LRP5	O75197-1.2	S141I	Neutral	0.027
LRP5	O75197-1.2	S141K	Neutral	0.007
LRP5	O75197-1.2	S141L	Neutral	0.03
LRP5	O75197-1.2	S141M	Neutral	0.015
LRP5	O75197-1.2	S141N	Neutral	0.003
LRP5	O75197-1.2	S141P	Neutral	0.025
LRP5	O75197-1.2	S141Q	Neutral	0.013
LRP5	O75197-1.2	S141R	Neutral	0.019
LRP5	O75197-1.2	S141T	Neutral	0.004
LRP5	O75197-1.2	S141V	Neutral	0.046
LRP5	O75197-1.2	S141W	Neutral	0.051
LRP5	O75197-1.2	S141Y	Neutral	0.055
LRP5	O75197-1.2	R142A	Pathogenic	0.845
LRP5	O75197-1.2	R142C	Pathogenic	0.966
LRP5	O75197-1.2	R142D	Pathogenic	0.978
LRP5	O75197-1.2	R142E	Pathogenic	0.817
LRP5	O75197-1.2	R142F	Pathogenic	0.937
LRP5	O75197-1.2	R142G	Pathogenic	0.955
LRP5	O75197-1.2	R142H	Pathogenic	0.694
LRP5	O75197-1.2	R142I	Pathogenic	0.935
LRP5	O75197-1.2	R142K	Neutral	0.408
LRP5	O75197-1.2	R142L	Pathogenic	0.839
LRP5	O75197-1.2	R142M	Pathogenic	0.723
LRP5	O75197-1.2	R142N	Pathogenic	0.809
LRP5	O75197-1.2	R142P	Pathogenic	0.922
LRP5	O75197-1.2	R142Q	Pathogenic	0.504
LRP5	O75197-1.2	R142S	Pathogenic	0.882
LRP5	O75197-1.2	R142T	Pathogenic	0.856
LRP5	O75197-1.2	R142V	Pathogenic	0.96
LRP5	O75197-1.2	R142W	Pathogenic	0.908
LRP5	O75197-1.2	R142Y	Pathogenic	0.912
LRP5	O75197-1.2	K143A	Pathogenic	0.896
LRP5	O75197-1.2	K143C	Pathogenic	0.978
LRP5	O75197-1.2	K143D	Pathogenic	0.959
LRP5	O75197-1.2	K143E	Pathogenic	0.698
LRP5	O75197-1.2	K143F	Pathogenic	0.959
LRP5	O75197-1.2	K143G	Pathogenic	0.971
LRP5	O75197-1.2	K143H	Pathogenic	0.916
LRP5	O75197-1.2	K143I	Pathogenic	0.958
LRP5	O75197-1.2	K143L	Pathogenic	0.892
LRP5	O75197-1.2	K143M	Pathogenic	0.805
LRP5	O75197-1.2	K143N	Pathogenic	0.87
LRP5	O75197-1.2	K143P	Pathogenic	0.861
LRP5	O75197-1.2	K143Q	Pathogenic	0.616
LRP5	O75197-1.2	K143R	Pathogenic	0.512
LRP5	O75197-1.2	K143S	Pathogenic	0.795
LRP5	O75197-1.2	K143T	Pathogenic	0.904
LRP5	O75197-1.2	K143V	Pathogenic	0.925
LRP5	O75197-1.2	K143W	Pathogenic	0.937
LRP5	O75197-1.2	K143Y	Pathogenic	0.942
LRP5	O75197-1.2	V144A	Pathogenic	0.704
LRP5	O75197-1.2	V144C	Pathogenic	0.932
LRP5	O75197-1.2	V144D	Pathogenic	0.964
LRP5	O75197-1.2	V144E	Pathogenic	0.909
LRP5	O75197-1.2	V144F	Pathogenic	0.908
LRP5	O75197-1.2	V144G	Pathogenic	0.98
LRP5	O75197-1.2	V144H	Pathogenic	0.983
LRP5	O75197-1.2	V144I	Neutral	0.104
LRP5	O75197-1.2	V144K	Pathogenic	0.875
LRP5	O75197-1.2	V144L	Pathogenic	0.541
LRP5	O75197-1.2	V144M	Pathogenic	0.642
LRP5	O75197-1.2	V144N	Pathogenic	0.969
LRP5	O75197-1.2	V144P	Pathogenic	0.971
LRP5	O75197-1.2	V144Q	Pathogenic	0.935
LRP5	O75197-1.2	V144R	Pathogenic	0.954
LRP5	O75197-1.2	V144S	Pathogenic	0.942
LRP5	O75197-1.2	V144T	Pathogenic	0.703
LRP5	O75197-1.2	V144W	Pathogenic	0.983
LRP5	O75197-1.2	V144Y	Pathogenic	0.929
LRP5	O75197-1.2	L145A	Pathogenic	0.742
LRP5	O75197-1.2	L145C	Pathogenic	0.844
LRP5	O75197-1.2	L145D	Pathogenic	0.97
LRP5	O75197-1.2	L145E	Pathogenic	0.924
LRP5	O75197-1.2	L145F	Pathogenic	0.766
LRP5	O75197-1.2	L145G	Pathogenic	0.984
LRP5	O75197-1.2	L145H	Pathogenic	0.961
LRP5	O75197-1.2	L145I	Neutral	0.262
LRP5	O75197-1.2	L145K	Pathogenic	0.747
LRP5	O75197-1.2	L145M	Neutral	0.204
LRP5	O75197-1.2	L145N	Pathogenic	0.925
LRP5	O75197-1.2	L145P	Pathogenic	0.976
LRP5	O75197-1.2	L145Q	Pathogenic	0.855
LRP5	O75197-1.2	L145R	Pathogenic	0.74
LRP5	O75197-1.2	L145S	Pathogenic	0.866
LRP5	O75197-1.2	L145T	Pathogenic	0.741
LRP5	O75197-1.2	L145V	Neutral	0.427
LRP5	O75197-1.2	L145W	Pathogenic	0.95
LRP5	O75197-1.2	L145Y	Pathogenic	0.846
LRP5	O75197-1.2	F146A	Pathogenic	0.959
LRP5	O75197-1.2	F146C	Pathogenic	0.978
LRP5	O75197-1.2	F146D	Pathogenic	0.966
LRP5	O75197-1.2	F146E	Pathogenic	0.971
LRP5	O75197-1.2	F146G	Pathogenic	0.981
LRP5	O75197-1.2	F146H	Pathogenic	0.878
LRP5	O75197-1.2	F146I	Pathogenic	0.912
LRP5	O75197-1.2	F146K	Pathogenic	0.962
LRP5	O75197-1.2	F146L	Pathogenic	0.907
LRP5	O75197-1.2	F146M	Pathogenic	0.864
LRP5	O75197-1.2	F146N	Pathogenic	0.971
LRP5	O75197-1.2	F146P	Pathogenic	0.997
LRP5	O75197-1.2	F146Q	Pathogenic	0.98
LRP5	O75197-1.2	F146R	Pathogenic	0.96
LRP5	O75197-1.2	F146S	Pathogenic	0.946
LRP5	O75197-1.2	F146T	Pathogenic	0.959
LRP5	O75197-1.2	F146V	Pathogenic	0.949
LRP5	O75197-1.2	F146W	Pathogenic	0.69
LRP5	O75197-1.2	F146Y	Neutral	0.152
LRP5	O75197-1.2	W147A	Pathogenic	0.991
LRP5	O75197-1.2	W147C	Pathogenic	0.985
LRP5	O75197-1.2	W147D	Pathogenic	0.992
LRP5	O75197-1.2	W147E	Pathogenic	0.98
LRP5	O75197-1.2	W147F	Pathogenic	0.84
LRP5	O75197-1.2	W147G	Pathogenic	0.963
LRP5	O75197-1.2	W147H	Pathogenic	0.97
LRP5	O75197-1.2	W147I	Pathogenic	0.998
LRP5	O75197-1.2	W147K	Pathogenic	0.974
LRP5	O75197-1.2	W147L	Pathogenic	0.993
LRP5	O75197-1.2	W147M	Pathogenic	0.967
LRP5	O75197-1.2	W147N	Pathogenic	0.993
LRP5	O75197-1.2	W147P	Pathogenic	0.998
LRP5	O75197-1.2	W147Q	Pathogenic	0.959
LRP5	O75197-1.2	W147R	Pathogenic	0.974
LRP5	O75197-1.2	W147S	Pathogenic	0.988
LRP5	O75197-1.2	W147T	Pathogenic	0.972
LRP5	O75197-1.2	W147V	Pathogenic	0.996
LRP5	O75197-1.2	W147Y	Neutral	0.453
LRP5	O75197-1.2	Q148A	Neutral	0.455
LRP5	O75197-1.2	Q148C	Pathogenic	0.813
LRP5	O75197-1.2	Q148D	Neutral	0.219
LRP5	O75197-1.2	Q148E	Neutral	0.034
LRP5	O75197-1.2	Q148F	Pathogenic	0.682
LRP5	O75197-1.2	Q148G	Pathogenic	0.764
LRP5	O75197-1.2	Q148H	Neutral	0.256
LRP5	O75197-1.2	Q148I	Pathogenic	0.683
LRP5	O75197-1.2	Q148K	Neutral	0.07
LRP5	O75197-1.2	Q148L	Neutral	0.437
LRP5	O75197-1.2	Q148M	Neutral	0.113
LRP5	O75197-1.2	Q148N	Neutral	0.247
LRP5	O75197-1.2	Q148P	Neutral	0.375
LRP5	O75197-1.2	Q148R	Neutral	0.068
LRP5	O75197-1.2	Q148S	Neutral	0.274
LRP5	O75197-1.2	Q148T	Neutral	0.477
LRP5	O75197-1.2	Q148V	Pathogenic	0.545
LRP5	O75197-1.2	Q148W	Neutral	0.308
LRP5	O75197-1.2	Q148Y	Neutral	0.325
LRP5	O75197-1.2	D149A	Neutral	0.339
LRP5	O75197-1.2	D149C	Neutral	0.468
LRP5	O75197-1.2	D149E	Neutral	0.014
LRP5	O75197-1.2	D149F	Neutral	0.287
LRP5	O75197-1.2	D149G	Neutral	0.177
LRP5	O75197-1.2	D149H	Neutral	0.164
LRP5	O75197-1.2	D149I	Neutral	0.288
LRP5	O75197-1.2	D149K	Neutral	0.26
LRP5	O75197-1.2	D149L	Pathogenic	0.574
LRP5	O75197-1.2	D149M	Neutral	0.402
LRP5	O75197-1.2	D149N	Neutral	0.041
LRP5	O75197-1.2	D149P	Neutral	0.108
LRP5	O75197-1.2	D149Q	Neutral	0.082
LRP5	O75197-1.2	D149R	Pathogenic	0.508
LRP5	O75197-1.2	D149S	Neutral	0.071
LRP5	O75197-1.2	D149T	Neutral	0.155
LRP5	O75197-1.2	D149V	Neutral	0.413
LRP5	O75197-1.2	D149W	Neutral	0.436
LRP5	O75197-1.2	D149Y	Neutral	0.455
LRP5	O75197-1.2	L150A	Neutral	0.439
LRP5	O75197-1.2	L150C	Pathogenic	0.596
LRP5	O75197-1.2	L150D	Pathogenic	0.897
LRP5	O75197-1.2	L150E	Pathogenic	0.769
LRP5	O75197-1.2	L150F	Neutral	0.471
LRP5	O75197-1.2	L150G	Pathogenic	0.942
LRP5	O75197-1.2	L150H	Pathogenic	0.871
LRP5	O75197-1.2	L150I	Neutral	0.088
LRP5	O75197-1.2	L150K	Neutral	0.446
LRP5	O75197-1.2	L150M	Neutral	0.065
LRP5	O75197-1.2	L150N	Pathogenic	0.771
LRP5	O75197-1.2	L150P	Pathogenic	0.916
LRP5	O75197-1.2	L150Q	Pathogenic	0.616
LRP5	O75197-1.2	L150R	Neutral	0.438
LRP5	O75197-1.2	L150S	Pathogenic	0.639
LRP5	O75197-1.2	L150T	Neutral	0.438
LRP5	O75197-1.2	L150V	Neutral	0.169
LRP5	O75197-1.2	L150W	Pathogenic	0.839
LRP5	O75197-1.2	L150Y	Pathogenic	0.6
LRP5	O75197-1.2	D151A	Pathogenic	0.783
LRP5	O75197-1.2	D151C	Pathogenic	0.861
LRP5	O75197-1.2	D151E	Neutral	0.09
LRP5	O75197-1.2	D151F	Pathogenic	0.739
LRP5	O75197-1.2	D151G	Pathogenic	0.603
LRP5	O75197-1.2	D151H	Pathogenic	0.581
LRP5	O75197-1.2	D151I	Pathogenic	0.74
LRP5	O75197-1.2	D151K	Pathogenic	0.713
LRP5	O75197-1.2	D151L	Pathogenic	0.905
LRP5	O75197-1.2	D151M	Pathogenic	0.826
LRP5	O75197-1.2	D151N	Neutral	0.23
LRP5	O75197-1.2	D151P	Neutral	0.461
LRP5	O75197-1.2	D151Q	Neutral	0.386
LRP5	O75197-1.2	D151R	Pathogenic	0.879
LRP5	O75197-1.2	D151S	Neutral	0.349
LRP5	O75197-1.2	D151T	Pathogenic	0.563
LRP5	O75197-1.2	D151V	Pathogenic	0.832
LRP5	O75197-1.2	D151W	Pathogenic	0.845
LRP5	O75197-1.2	D151Y	Pathogenic	0.855
LRP5	O75197-1.2	Q152A	Pathogenic	0.96
LRP5	O75197-1.2	Q152C	Pathogenic	0.992
LRP5	O75197-1.2	Q152D	Pathogenic	0.889
LRP5	O75197-1.2	Q152E	Neutral	0.499
LRP5	O75197-1.2	Q152F	Pathogenic	0.984
LRP5	O75197-1.2	Q152G	Pathogenic	0.989
LRP5	O75197-1.2	Q152H	Pathogenic	0.908
LRP5	O75197-1.2	Q152I	Pathogenic	0.984
LRP5	O75197-1.2	Q152K	Pathogenic	0.684
LRP5	O75197-1.2	Q152L	Pathogenic	0.957
LRP5	O75197-1.2	Q152M	Pathogenic	0.784
LRP5	O75197-1.2	Q152N	Pathogenic	0.903
LRP5	O75197-1.2	Q152P	Pathogenic	0.945
LRP5	O75197-1.2	Q152R	Pathogenic	0.676
LRP5	O75197-1.2	Q152S	Pathogenic	0.915
LRP5	O75197-1.2	Q152T	Pathogenic	0.963
LRP5	O75197-1.2	Q152V	Pathogenic	0.972
LRP5	O75197-1.2	Q152W	Pathogenic	0.927
LRP5	O75197-1.2	Q152Y	Pathogenic	0.932
LRP5	O75197-1.2	P153A	Pathogenic	0.932
LRP5	O75197-1.2	P153C	Pathogenic	0.993
LRP5	O75197-1.2	P153D	Pathogenic	0.844
LRP5	O75197-1.2	P153E	Pathogenic	0.855
LRP5	O75197-1.2	P153F	Pathogenic	0.995
LRP5	O75197-1.2	P153G	Pathogenic	0.968
LRP5	O75197-1.2	P153H	Pathogenic	0.972
LRP5	O75197-1.2	P153I	Pathogenic	0.985
LRP5	O75197-1.2	P153K	Pathogenic	0.805
LRP5	O75197-1.2	P153L	Pathogenic	0.987
LRP5	O75197-1.2	P153M	Pathogenic	0.974
LRP5	O75197-1.2	P153N	Pathogenic	0.95
LRP5	O75197-1.2	P153Q	Pathogenic	0.895
LRP5	O75197-1.2	P153R	Pathogenic	0.924
LRP5	O75197-1.2	P153S	Pathogenic	0.91
LRP5	O75197-1.2	P153T	Pathogenic	0.931
LRP5	O75197-1.2	P153V	Pathogenic	0.975
LRP5	O75197-1.2	P153W	Pathogenic	0.992
LRP5	O75197-1.2	P153Y	Pathogenic	0.993
LRP5	O75197-1.2	R154A	Pathogenic	0.844
LRP5	O75197-1.2	R154C	Pathogenic	0.966
LRP5	O75197-1.2	R154D	Pathogenic	0.978
LRP5	O75197-1.2	R154E	Pathogenic	0.815
LRP5	O75197-1.2	R154F	Pathogenic	0.937
LRP5	O75197-1.2	R154G	Pathogenic	0.954
LRP5	O75197-1.2	R154H	Pathogenic	0.692
LRP5	O75197-1.2	R154I	Pathogenic	0.935
LRP5	O75197-1.2	R154K	Neutral	0.405
LRP5	O75197-1.2	R154L	Pathogenic	0.838
LRP5	O75197-1.2	R154M	Pathogenic	0.721
LRP5	O75197-1.2	R154N	Pathogenic	0.807
LRP5	O75197-1.2	R154P	Pathogenic	0.922
LRP5	O75197-1.2	R154Q	Pathogenic	0.502
LRP5	O75197-1.2	R154S	Pathogenic	0.881
LRP5	O75197-1.2	R154T	Pathogenic	0.855
LRP5	O75197-1.2	R154V	Pathogenic	0.959
LRP5	O75197-1.2	R154W	Pathogenic	0.907
LRP5	O75197-1.2	R154Y	Pathogenic	0.912
LRP5	O75197-1.2	A155C	Pathogenic	0.779
LRP5	O75197-1.2	A155D	Pathogenic	0.958
LRP5	O75197-1.2	A155E	Pathogenic	0.89
LRP5	O75197-1.2	A155F	Pathogenic	0.936
LRP5	O75197-1.2	A155G	Pathogenic	0.831
LRP5	O75197-1.2	A155H	Pathogenic	0.98
LRP5	O75197-1.2	A155I	Pathogenic	0.829
LRP5	O75197-1.2	A155K	Pathogenic	0.851
LRP5	O75197-1.2	A155L	Pathogenic	0.842
LRP5	O75197-1.2	A155M	Pathogenic	0.89
LRP5	O75197-1.2	A155N	Pathogenic	0.963
LRP5	O75197-1.2	A155P	Pathogenic	0.931
LRP5	O75197-1.2	A155Q	Pathogenic	0.921
LRP5	O75197-1.2	A155R	Pathogenic	0.846
LRP5	O75197-1.2	A155S	Pathogenic	0.614
LRP5	O75197-1.2	A155T	Pathogenic	0.859
LRP5	O75197-1.2	A155V	Pathogenic	0.735
LRP5	O75197-1.2	A155W	Pathogenic	0.966
LRP5	O75197-1.2	A155Y	Pathogenic	0.968
LRP5	O75197-1.2	I156A	Pathogenic	0.766
LRP5	O75197-1.2	I156C	Pathogenic	0.86
LRP5	O75197-1.2	I156D	Pathogenic	0.923
LRP5	O75197-1.2	I156E	Pathogenic	0.933
LRP5	O75197-1.2	I156F	Pathogenic	0.813
LRP5	O75197-1.2	I156G	Pathogenic	0.985
LRP5	O75197-1.2	I156H	Pathogenic	0.966
LRP5	O75197-1.2	I156K	Pathogenic	0.911
LRP5	O75197-1.2	I156L	Neutral	0.307
LRP5	O75197-1.2	I156M	Neutral	0.469
LRP5	O75197-1.2	I156N	Pathogenic	0.934
LRP5	O75197-1.2	I156P	Pathogenic	0.978
LRP5	O75197-1.2	I156Q	Pathogenic	0.953
LRP5	O75197-1.2	I156R	Pathogenic	0.908
LRP5	O75197-1.2	I156S	Pathogenic	0.881
LRP5	O75197-1.2	I156T	Pathogenic	0.765
LRP5	O75197-1.2	I156V	Neutral	0.084
LRP5	O75197-1.2	I156W	Pathogenic	0.988
LRP5	O75197-1.2	I156Y	Pathogenic	0.862
LRP5	O75197-1.2	A157C	Pathogenic	0.66
LRP5	O75197-1.2	A157D	Pathogenic	0.925
LRP5	O75197-1.2	A157E	Pathogenic	0.817
LRP5	O75197-1.2	A157F	Pathogenic	0.89
LRP5	O75197-1.2	A157G	Pathogenic	0.729
LRP5	O75197-1.2	A157H	Pathogenic	0.964
LRP5	O75197-1.2	A157I	Pathogenic	0.727
LRP5	O75197-1.2	A157K	Pathogenic	0.757
LRP5	O75197-1.2	A157L	Pathogenic	0.745
LRP5	O75197-1.2	A157M	Pathogenic	0.816
LRP5	O75197-1.2	A157N	Pathogenic	0.935
LRP5	O75197-1.2	A157P	Pathogenic	0.881
LRP5	O75197-1.2	A157Q	Pathogenic	0.865
LRP5	O75197-1.2	A157R	Pathogenic	0.751
LRP5	O75197-1.2	A157S	Neutral	0.466
LRP5	O75197-1.2	A157T	Pathogenic	0.77
LRP5	O75197-1.2	A157V	Pathogenic	0.604
LRP5	O75197-1.2	A157W	Pathogenic	0.939
LRP5	O75197-1.2	A157Y	Pathogenic	0.944
LRP5	O75197-1.2	L158A	Pathogenic	0.701
LRP5	O75197-1.2	L158C	Pathogenic	0.816
LRP5	O75197-1.2	L158D	Pathogenic	0.963
LRP5	O75197-1.2	L158E	Pathogenic	0.909
LRP5	O75197-1.2	L158F	Pathogenic	0.727
LRP5	O75197-1.2	L158G	Pathogenic	0.98
LRP5	O75197-1.2	L158H	Pathogenic	0.953
LRP5	O75197-1.2	L158I	Neutral	0.224
LRP5	O75197-1.2	L158K	Pathogenic	0.707
LRP5	O75197-1.2	L158M	Neutral	0.173
LRP5	O75197-1.2	L158N	Pathogenic	0.91
LRP5	O75197-1.2	L158P	Pathogenic	0.97
LRP5	O75197-1.2	L158Q	Pathogenic	0.828
LRP5	O75197-1.2	L158R	Pathogenic	0.699
LRP5	O75197-1.2	L158S	Pathogenic	0.841
LRP5	O75197-1.2	L158T	Pathogenic	0.7
LRP5	O75197-1.2	L158V	Neutral	0.378
LRP5	O75197-1.2	L158W	Pathogenic	0.94
LRP5	O75197-1.2	L158Y	Pathogenic	0.818
LRP5	O75197-1.2	D159A	Neutral	0.488
LRP5	O75197-1.2	D159C	Pathogenic	0.62
LRP5	O75197-1.2	D159E	Neutral	0.026
LRP5	O75197-1.2	D159F	Neutral	0.427
LRP5	O75197-1.2	D159G	Neutral	0.286
LRP5	O75197-1.2	D159H	Neutral	0.267
LRP5	O75197-1.2	D159I	Neutral	0.429
LRP5	O75197-1.2	D159K	Neutral	0.395
LRP5	O75197-1.2	D159L	Pathogenic	0.714
LRP5	O75197-1.2	D159M	Pathogenic	0.556
LRP5	O75197-1.2	D159N	Neutral	0.073
LRP5	O75197-1.2	D159P	Neutral	0.184
LRP5	O75197-1.2	D159Q	Neutral	0.142
LRP5	O75197-1.2	D159R	Pathogenic	0.658
LRP5	O75197-1.2	D159S	Neutral	0.124
LRP5	O75197-1.2	D159T	Neutral	0.254
LRP5	O75197-1.2	D159V	Pathogenic	0.566
LRP5	O75197-1.2	D159W	Pathogenic	0.59
LRP5	O75197-1.2	D159Y	Pathogenic	0.608
LRP5	O75197-1.2	P160A	Pathogenic	0.935
LRP5	O75197-1.2	P160C	Pathogenic	0.994
LRP5	O75197-1.2	P160D	Pathogenic	0.851
LRP5	O75197-1.2	P160E	Pathogenic	0.862
LRP5	O75197-1.2	P160F	Pathogenic	0.995
LRP5	O75197-1.2	P160G	Pathogenic	0.97
LRP5	O75197-1.2	P160H	Pathogenic	0.974
LRP5	O75197-1.2	P160I	Pathogenic	0.986
LRP5	O75197-1.2	P160K	Pathogenic	0.814
LRP5	O75197-1.2	P160L	Pathogenic	0.987
LRP5	O75197-1.2	P160M	Pathogenic	0.975
LRP5	O75197-1.2	P160N	Pathogenic	0.952
LRP5	O75197-1.2	P160Q	Pathogenic	0.9
LRP5	O75197-1.2	P160R	Pathogenic	0.928
LRP5	O75197-1.2	P160S	Pathogenic	0.915
LRP5	O75197-1.2	P160T	Pathogenic	0.934
LRP5	O75197-1.2	P160V	Pathogenic	0.976
LRP5	O75197-1.2	P160W	Pathogenic	0.993
LRP5	O75197-1.2	P160Y	Pathogenic	0.993
LRP5	O75197-1.2	A161C	Neutral	0.013
LRP5	O75197-1.2	A161D	Neutral	0.08
LRP5	O75197-1.2	A161E	Neutral	0.03
LRP5	O75197-1.2	A161F	Neutral	0.054
LRP5	O75197-1.2	A161G	Neutral	0.019
LRP5	O75197-1.2	A161H	Neutral	0.157
LRP5	O75197-1.2	A161I	Neutral	0.018
LRP5	O75197-1.2	A161K	Neutral	0.021
LRP5	O75197-1.2	A161L	Neutral	0.02
LRP5	O75197-1.2	A161M	Neutral	0.03
LRP5	O75197-1.2	A161N	Neutral	0.091
LRP5	O75197-1.2	A161P	Neutral	0.05
LRP5	O75197-1.2	A161Q	Neutral	0.043
LRP5	O75197-1.2	A161R	Neutral	0.021
LRP5	O75197-1.2	A161S	Neutral	0.006
LRP5	O75197-1.2	A161T	Neutral	0.023
LRP5	O75197-1.2	A161V	Neutral	0.011
LRP5	O75197-1.2	A161W	Neutral	0.098
LRP5	O75197-1.2	A161Y	Neutral	0.105
LRP5	O75197-1.2	H162A	Neutral	0.239
LRP5	O75197-1.2	H162C	Neutral	0.35
LRP5	O75197-1.2	H162D	Neutral	0.053
LRP5	O75197-1.2	H162E	Neutral	0.021
LRP5	O75197-1.2	H162F	Neutral	0.028
LRP5	O75197-1.2	H162G	Neutral	0.24
LRP5	O75197-1.2	H162I	Neutral	0.212
LRP5	O75197-1.2	H162K	Neutral	0.045
LRP5	O75197-1.2	H162L	Neutral	0.228
LRP5	O75197-1.2	H162M	Neutral	0.129
LRP5	O75197-1.2	H162N	Neutral	0.007
LRP5	O75197-1.2	H162P	Neutral	0.184
LRP5	O75197-1.2	H162Q	Neutral	0.03
LRP5	O75197-1.2	H162R	Neutral	0.015
LRP5	O75197-1.2	H162S	Neutral	0.095
LRP5	O75197-1.2	H162T	Neutral	0.255
LRP5	O75197-1.2	H162V	Neutral	0.31
LRP5	O75197-1.2	H162W	Neutral	0.053
LRP5	O75197-1.2	H162Y	Neutral	0.002
LRP5	O75197-1.2	G163A	Neutral	0.47
LRP5	O75197-1.2	G163C	Pathogenic	0.93
LRP5	O75197-1.2	G163D	Pathogenic	0.632
LRP5	O75197-1.2	G163E	Pathogenic	0.851
LRP5	O75197-1.2	G163F	Pathogenic	0.856
LRP5	O75197-1.2	G163H	Pathogenic	0.899
LRP5	O75197-1.2	G163I	Pathogenic	0.948
LRP5	O75197-1.2	G163K	Pathogenic	0.8
LRP5	O75197-1.2	G163L	Pathogenic	0.952
LRP5	O75197-1.2	G163M	Pathogenic	0.909
LRP5	O75197-1.2	G163N	Neutral	0.395
LRP5	O75197-1.2	G163P	Pathogenic	0.846
LRP5	O75197-1.2	G163Q	Pathogenic	0.892
LRP5	O75197-1.2	G163R	Pathogenic	0.795
LRP5	O75197-1.2	G163S	Pathogenic	0.529
LRP5	O75197-1.2	G163T	Pathogenic	0.892
LRP5	O75197-1.2	G163V	Pathogenic	0.913
LRP5	O75197-1.2	G163W	Pathogenic	0.554
LRP5	O75197-1.2	G163Y	Pathogenic	0.925
LRP5	O75197-1.2	Y164A	Pathogenic	0.529
LRP5	O75197-1.2	Y164C	Pathogenic	0.671
LRP5	O75197-1.2	Y164D	Pathogenic	0.575
LRP5	O75197-1.2	Y164E	Neutral	0.34
LRP5	O75197-1.2	Y164F	Neutral	0.004
LRP5	O75197-1.2	Y164G	Pathogenic	0.716
LRP5	O75197-1.2	Y164H	Neutral	0.012
LRP5	O75197-1.2	Y164I	Neutral	0.254
LRP5	O75197-1.2	Y164K	Neutral	0.282
LRP5	O75197-1.2	Y164L	Neutral	0.272
LRP5	O75197-1.2	Y164M	Neutral	0.363
LRP5	O75197-1.2	Y164N	Neutral	0.343
LRP5	O75197-1.2	Y164P	Pathogenic	0.837
LRP5	O75197-1.2	Y164Q	Neutral	0.199
LRP5	O75197-1.2	Y164R	Neutral	0.279
LRP5	O75197-1.2	Y164S	Neutral	0.455
LRP5	O75197-1.2	Y164T	Pathogenic	0.528
LRP5	O75197-1.2	Y164V	Neutral	0.359
LRP5	O75197-1.2	Y164W	Neutral	0.008
LRP5	O75197-1.2	M165A	Pathogenic	0.985
LRP5	O75197-1.2	M165C	Pathogenic	0.992
LRP5	O75197-1.2	M165D	Pathogenic	0.996
LRP5	O75197-1.2	M165E	Pathogenic	0.989
LRP5	O75197-1.2	M165F	Pathogenic	0.97
LRP5	O75197-1.2	M165G	Pathogenic	0.998
LRP5	O75197-1.2	M165H	Pathogenic	0.995
LRP5	O75197-1.2	M165I	Pathogenic	0.916
LRP5	O75197-1.2	M165K	Pathogenic	0.958
LRP5	O75197-1.2	M165L	Pathogenic	0.796
LRP5	O75197-1.2	M165N	Pathogenic	0.99
LRP5	O75197-1.2	M165P	Pathogenic	0.997
LRP5	O75197-1.2	M165Q	Pathogenic	0.937
LRP5	O75197-1.2	M165R	Pathogenic	0.956
LRP5	O75197-1.2	M165S	Pathogenic	0.98
LRP5	O75197-1.2	M165T	Pathogenic	0.985
LRP5	O75197-1.2	M165V	Pathogenic	0.945
LRP5	O75197-1.2	M165W	Pathogenic	0.984
LRP5	O75197-1.2	M165Y	Pathogenic	0.992
LRP5	O75197-1.2	Y166A	Pathogenic	0.99
LRP5	O75197-1.2	Y166C	Pathogenic	0.994
LRP5	O75197-1.2	Y166D	Pathogenic	0.991
LRP5	O75197-1.2	Y166E	Pathogenic	0.977
LRP5	O75197-1.2	Y166F	Neutral	0.256
LRP5	O75197-1.2	Y166G	Pathogenic	0.995
LRP5	O75197-1.2	Y166H	Pathogenic	0.505
LRP5	O75197-1.2	Y166I	Pathogenic	0.966
LRP5	O75197-1.2	Y166K	Pathogenic	0.971
LRP5	O75197-1.2	Y166L	Pathogenic	0.969
LRP5	O75197-1.2	Y166M	Pathogenic	0.979
LRP5	O75197-1.2	Y166N	Pathogenic	0.978
LRP5	O75197-1.2	Y166P	Pathogenic	0.998
LRP5	O75197-1.2	Y166Q	Pathogenic	0.954
LRP5	O75197-1.2	Y166R	Pathogenic	0.97
LRP5	O75197-1.2	Y166S	Pathogenic	0.986
LRP5	O75197-1.2	Y166T	Pathogenic	0.989
LRP5	O75197-1.2	Y166V	Pathogenic	0.979
LRP5	O75197-1.2	Y166W	Neutral	0.404
LRP5	O75197-1.2	W167A	Pathogenic	0.999
LRP5	O75197-1.2	W167C	Pathogenic	0.998
LRP5	O75197-1.2	W167D	Pathogenic	0.999
LRP5	O75197-1.2	W167E	Pathogenic	0.998
LRP5	O75197-1.2	W167F	Pathogenic	0.981
LRP5	O75197-1.2	W167G	Pathogenic	0.996
LRP5	O75197-1.2	W167H	Pathogenic	0.997
LRP5	O75197-1.2	W167I	Pathogenic	1.0
LRP5	O75197-1.2	W167K	Pathogenic	0.997
LRP5	O75197-1.2	W167L	Pathogenic	0.999
LRP5	O75197-1.2	W167M	Pathogenic	0.997
LRP5	O75197-1.2	W167N	Pathogenic	0.999
LRP5	O75197-1.2	W167P	Pathogenic	1.0
LRP5	O75197-1.2	W167Q	Pathogenic	0.996
LRP5	O75197-1.2	W167R	Pathogenic	0.997
LRP5	O75197-1.2	W167S	Pathogenic	0.999
LRP5	O75197-1.2	W167T	Pathogenic	0.997
LRP5	O75197-1.2	W167V	Pathogenic	1.0
LRP5	O75197-1.2	W167Y	Pathogenic	0.891
LRP5	O75197-1.2	T168A	Pathogenic	0.979
LRP5	O75197-1.2	T168C	Pathogenic	0.988
LRP5	O75197-1.2	T168D	Pathogenic	0.984
LRP5	O75197-1.2	T168E	Pathogenic	0.986
LRP5	O75197-1.2	T168F	Pathogenic	0.991
LRP5	O75197-1.2	T168G	Pathogenic	0.997
LRP5	O75197-1.2	T168H	Pathogenic	0.998
LRP5	O75197-1.2	T168I	Pathogenic	0.974
LRP5	O75197-1.2	T168K	Pathogenic	0.98
LRP5	O75197-1.2	T168L	Pathogenic	0.976
LRP5	O75197-1.2	T168M	Pathogenic	0.984
LRP5	O75197-1.2	T168N	Pathogenic	0.96
LRP5	O75197-1.2	T168P	Pathogenic	0.99
LRP5	O75197-1.2	T168Q	Pathogenic	0.99
LRP5	O75197-1.2	T168R	Pathogenic	0.979
LRP5	O75197-1.2	T168S	Pathogenic	0.927
LRP5	O75197-1.2	T168V	Pathogenic	0.956
LRP5	O75197-1.2	T168W	Pathogenic	0.986
LRP5	O75197-1.2	T168Y	Pathogenic	0.996
LRP5	O75197-1.2	D169A	Pathogenic	0.994
LRP5	O75197-1.2	D169C	Pathogenic	0.996
LRP5	O75197-1.2	D169E	Pathogenic	0.815
LRP5	O75197-1.2	D169F	Pathogenic	0.992
LRP5	O75197-1.2	D169G	Pathogenic	0.985
LRP5	O75197-1.2	D169H	Pathogenic	0.984
LRP5	O75197-1.2	D169I	Pathogenic	0.992
LRP5	O75197-1.2	D169K	Pathogenic	0.991
LRP5	O75197-1.2	D169L	Pathogenic	0.998
LRP5	O75197-1.2	D169M	Pathogenic	0.995
LRP5	O75197-1.2	D169N	Pathogenic	0.93
LRP5	O75197-1.2	D169P	Pathogenic	0.974
LRP5	O75197-1.2	D169Q	Pathogenic	0.965
LRP5	O75197-1.2	D169R	Pathogenic	0.997
LRP5	O75197-1.2	D169S	Pathogenic	0.96
LRP5	O75197-1.2	D169T	Pathogenic	0.983
LRP5	O75197-1.2	D169V	Pathogenic	0.995
LRP5	O75197-1.2	D169W	Pathogenic	0.996
LRP5	O75197-1.2	D169Y	Pathogenic	0.996
LRP5	O75197-1.2	W170A	Pathogenic	0.999
LRP5	O75197-1.2	W170C	Pathogenic	0.999
LRP5	O75197-1.2	W170D	Pathogenic	0.999
LRP5	O75197-1.2	W170E	Pathogenic	0.998
LRP5	O75197-1.2	W170F	Pathogenic	0.982
LRP5	O75197-1.2	W170G	Pathogenic	0.996
LRP5	O75197-1.2	W170H	Pathogenic	0.997
LRP5	O75197-1.2	W170I	Pathogenic	1.0
LRP5	O75197-1.2	W170K	Pathogenic	0.997
LRP5	O75197-1.2	W170L	Pathogenic	0.999
LRP5	O75197-1.2	W170M	Pathogenic	0.997
LRP5	O75197-1.2	W170N	Pathogenic	0.999
LRP5	O75197-1.2	W170P	Pathogenic	1.0
LRP5	O75197-1.2	W170Q	Pathogenic	0.996
LRP5	O75197-1.2	W170R	Pathogenic	0.997
LRP5	O75197-1.2	W170S	Pathogenic	0.999
LRP5	O75197-1.2	W170T	Pathogenic	0.997
LRP5	O75197-1.2	W170V	Pathogenic	1.0
LRP5	O75197-1.2	W170Y	Pathogenic	0.894
LRP5	O75197-1.2	G171A	Pathogenic	0.978
LRP5	O75197-1.2	G171C	Pathogenic	0.998
LRP5	O75197-1.2	G171D	Pathogenic	0.988
LRP5	O75197-1.2	G171E	Pathogenic	0.997
LRP5	O75197-1.2	G171F	Pathogenic	0.997
LRP5	O75197-1.2	G171H	Pathogenic	0.998
LRP5	O75197-1.2	G171I	Pathogenic	0.999
LRP5	O75197-1.2	G171K	Pathogenic	0.995
LRP5	O75197-1.2	G171L	Pathogenic	0.999
LRP5	O75197-1.2	G171M	Pathogenic	0.998
LRP5	O75197-1.2	G171N	Pathogenic	0.97
LRP5	O75197-1.2	G171P	Pathogenic	0.996
LRP5	O75197-1.2	G171Q	Pathogenic	0.998
LRP5	O75197-1.2	G171R	Pathogenic	0.995
LRP5	O75197-1.2	G171S	Pathogenic	0.982
LRP5	O75197-1.2	G171T	Pathogenic	0.998
LRP5	O75197-1.2	G171V	Pathogenic	0.998
LRP5	O75197-1.2	G171W	Pathogenic	0.984
LRP5	O75197-1.2	G171Y	Pathogenic	0.998
LRP5	O75197-1.2	E172A	Pathogenic	0.966
LRP5	O75197-1.2	E172C	Pathogenic	0.998
LRP5	O75197-1.2	E172D	Pathogenic	0.681
LRP5	O75197-1.2	E172F	Pathogenic	0.986
LRP5	O75197-1.2	E172G	Pathogenic	0.991
LRP5	O75197-1.2	E172H	Pathogenic	0.919
LRP5	O75197-1.2	E172I	Pathogenic	0.986
LRP5	O75197-1.2	E172K	Pathogenic	0.841
LRP5	O75197-1.2	E172L	Pathogenic	0.987
LRP5	O75197-1.2	E172M	Pathogenic	0.975
LRP5	O75197-1.2	E172N	Pathogenic	0.956
LRP5	O75197-1.2	E172P	Pathogenic	0.953
LRP5	O75197-1.2	E172Q	Pathogenic	0.628
LRP5	O75197-1.2	E172R	Pathogenic	0.939
LRP5	O75197-1.2	E172S	Pathogenic	0.927
LRP5	O75197-1.2	E172T	Pathogenic	0.968
LRP5	O75197-1.2	E172V	Pathogenic	0.976
LRP5	O75197-1.2	E172W	Pathogenic	0.978
LRP5	O75197-1.2	E172Y	Pathogenic	0.98
LRP5	O75197-1.2	T173A	Neutral	0.028
LRP5	O75197-1.2	T173C	Neutral	0.046
LRP5	O75197-1.2	T173D	Neutral	0.036
LRP5	O75197-1.2	T173E	Neutral	0.04
LRP5	O75197-1.2	T173F	Neutral	0.064
LRP5	O75197-1.2	T173G	Neutral	0.175
LRP5	O75197-1.2	T173H	Neutral	0.197
LRP5	O75197-1.2	T173I	Neutral	0.022
LRP5	O75197-1.2	T173K	Neutral	0.028
LRP5	O75197-1.2	T173L	Neutral	0.024
LRP5	O75197-1.2	T173M	Neutral	0.036
LRP5	O75197-1.2	T173N	Neutral	0.014
LRP5	O75197-1.2	T173P	Neutral	0.058
LRP5	O75197-1.2	T173Q	Neutral	0.056
LRP5	O75197-1.2	T173R	Neutral	0.027
LRP5	O75197-1.2	T173S	Neutral	0.008
LRP5	O75197-1.2	T173V	Neutral	0.013
LRP5	O75197-1.2	T173W	Neutral	0.041
LRP5	O75197-1.2	T173Y	Neutral	0.124
LRP5	O75197-1.2	P174A	Pathogenic	0.993
LRP5	O75197-1.2	P174C	Pathogenic	0.999
LRP5	O75197-1.2	P174D	Pathogenic	0.983
LRP5	O75197-1.2	P174E	Pathogenic	0.984
LRP5	O75197-1.2	P174F	Pathogenic	1.0
LRP5	O75197-1.2	P174G	Pathogenic	0.997
LRP5	O75197-1.2	P174H	Pathogenic	0.997
LRP5	O75197-1.2	P174I	Pathogenic	0.999
LRP5	O75197-1.2	P174K	Pathogenic	0.978
LRP5	O75197-1.2	P174L	Pathogenic	0.999
LRP5	O75197-1.2	P174M	Pathogenic	0.997
LRP5	O75197-1.2	P174N	Pathogenic	0.995
LRP5	O75197-1.2	P174Q	Pathogenic	0.989
LRP5	O75197-1.2	P174R	Pathogenic	0.992
LRP5	O75197-1.2	P174S	Pathogenic	0.991
LRP5	O75197-1.2	P174T	Pathogenic	0.993
LRP5	O75197-1.2	P174V	Pathogenic	0.998
LRP5	O75197-1.2	P174W	Pathogenic	0.999
LRP5	O75197-1.2	P174Y	Pathogenic	0.999
LRP5	O75197-1.2	R175A	Pathogenic	0.531
LRP5	O75197-1.2	R175C	Pathogenic	0.855
LRP5	O75197-1.2	R175D	Pathogenic	0.904
LRP5	O75197-1.2	R175E	Neutral	0.481
LRP5	O75197-1.2	R175F	Pathogenic	0.757
LRP5	O75197-1.2	R175G	Pathogenic	0.815
LRP5	O75197-1.2	R175H	Neutral	0.321
LRP5	O75197-1.2	R175I	Pathogenic	0.751
LRP5	O75197-1.2	R175K	Neutral	0.125
LRP5	O75197-1.2	R175L	Pathogenic	0.521
LRP5	O75197-1.2	R175M	Neutral	0.352
LRP5	O75197-1.2	R175N	Neutral	0.468
LRP5	O75197-1.2	R175P	Pathogenic	0.712
LRP5	O75197-1.2	R175Q	Neutral	0.175
LRP5	O75197-1.2	R175S	Pathogenic	0.609
LRP5	O75197-1.2	R175T	Pathogenic	0.553
LRP5	O75197-1.2	R175V	Pathogenic	0.832
LRP5	O75197-1.2	R175W	Pathogenic	0.672
LRP5	O75197-1.2	R175Y	Pathogenic	0.684
LRP5	O75197-1.2	I176A	Pathogenic	0.98
LRP5	O75197-1.2	I176C	Pathogenic	0.989
LRP5	O75197-1.2	I176D	Pathogenic	0.994
LRP5	O75197-1.2	I176E	Pathogenic	0.995
LRP5	O75197-1.2	I176F	Pathogenic	0.985
LRP5	O75197-1.2	I176G	Pathogenic	0.999
LRP5	O75197-1.2	I176H	Pathogenic	0.998
LRP5	O75197-1.2	I176K	Pathogenic	0.993
LRP5	O75197-1.2	I176L	Pathogenic	0.869
LRP5	O75197-1.2	I176M	Pathogenic	0.93
LRP5	O75197-1.2	I176N	Pathogenic	0.995
LRP5	O75197-1.2	I176P	Pathogenic	0.999
LRP5	O75197-1.2	I176Q	Pathogenic	0.997
LRP5	O75197-1.2	I176R	Pathogenic	0.993
LRP5	O75197-1.2	I176S	Pathogenic	0.991
LRP5	O75197-1.2	I176T	Pathogenic	0.98
LRP5	O75197-1.2	I176V	Pathogenic	0.578
LRP5	O75197-1.2	I176W	Pathogenic	0.999
LRP5	O75197-1.2	I176Y	Pathogenic	0.989
LRP5	O75197-1.2	E177A	Pathogenic	0.991
LRP5	O75197-1.2	E177C	Pathogenic	0.999
LRP5	O75197-1.2	E177D	Pathogenic	0.891
LRP5	O75197-1.2	E177F	Pathogenic	0.996
LRP5	O75197-1.2	E177G	Pathogenic	0.998
LRP5	O75197-1.2	E177H	Pathogenic	0.978
LRP5	O75197-1.2	E177I	Pathogenic	0.996
LRP5	O75197-1.2	E177K	Pathogenic	0.953
LRP5	O75197-1.2	E177L	Pathogenic	0.997
LRP5	O75197-1.2	E177M	Pathogenic	0.993
LRP5	O75197-1.2	E177N	Pathogenic	0.988
LRP5	O75197-1.2	E177P	Pathogenic	0.987
LRP5	O75197-1.2	E177Q	Pathogenic	0.866
LRP5	O75197-1.2	E177R	Pathogenic	0.983
LRP5	O75197-1.2	E177S	Pathogenic	0.98
LRP5	O75197-1.2	E177T	Pathogenic	0.992
LRP5	O75197-1.2	E177V	Pathogenic	0.994
LRP5	O75197-1.2	E177W	Pathogenic	0.994
LRP5	O75197-1.2	E177Y	Pathogenic	0.995
LRP5	O75197-1.2	R178A	Pathogenic	0.954
LRP5	O75197-1.2	R178C	Pathogenic	0.991
LRP5	O75197-1.2	R178D	Pathogenic	0.994
LRP5	O75197-1.2	R178E	Pathogenic	0.944
LRP5	O75197-1.2	R178F	Pathogenic	0.983
LRP5	O75197-1.2	R178G	Pathogenic	0.988
LRP5	O75197-1.2	R178H	Pathogenic	0.896
LRP5	O75197-1.2	R178I	Pathogenic	0.982
LRP5	O75197-1.2	R178K	Pathogenic	0.723
LRP5	O75197-1.2	R178L	Pathogenic	0.952
LRP5	O75197-1.2	R178M	Pathogenic	0.908
LRP5	O75197-1.2	R178N	Pathogenic	0.941
LRP5	O75197-1.2	R178P	Pathogenic	0.978
LRP5	O75197-1.2	R178Q	Pathogenic	0.794
LRP5	O75197-1.2	R178S	Pathogenic	0.966
LRP5	O75197-1.2	R178T	Pathogenic	0.957
LRP5	O75197-1.2	R178V	Pathogenic	0.989
LRP5	O75197-1.2	R178W	Pathogenic	0.974
LRP5	O75197-1.2	R178Y	Pathogenic	0.975
LRP5	O75197-1.2	A179C	Pathogenic	0.971
LRP5	O75197-1.2	A179D	Pathogenic	0.995
LRP5	O75197-1.2	A179E	Pathogenic	0.987
LRP5	O75197-1.2	A179F	Pathogenic	0.993
LRP5	O75197-1.2	A179G	Pathogenic	0.979
LRP5	O75197-1.2	A179H	Pathogenic	0.998
LRP5	O75197-1.2	A179I	Pathogenic	0.979
LRP5	O75197-1.2	A179K	Pathogenic	0.982
LRP5	O75197-1.2	A179L	Pathogenic	0.981
LRP5	O75197-1.2	A179M	Pathogenic	0.987
LRP5	O75197-1.2	A179N	Pathogenic	0.996
LRP5	O75197-1.2	A179P	Pathogenic	0.992
LRP5	O75197-1.2	A179Q	Pathogenic	0.991
LRP5	O75197-1.2	A179R	Pathogenic	0.981
LRP5	O75197-1.2	A179S	Pathogenic	0.938
LRP5	O75197-1.2	A179T	Pathogenic	0.983
LRP5	O75197-1.2	A179V	Pathogenic	0.963
LRP5	O75197-1.2	A179W	Pathogenic	0.996
LRP5	O75197-1.2	A179Y	Pathogenic	0.997
LRP5	O75197-1.2	G180A	Pathogenic	0.893
LRP5	O75197-1.2	G180C	Pathogenic	0.992
LRP5	O75197-1.2	G180D	Pathogenic	0.942
LRP5	O75197-1.2	G180E	Pathogenic	0.982
LRP5	O75197-1.2	G180F	Pathogenic	0.982
LRP5	O75197-1.2	G180H	Pathogenic	0.988
LRP5	O75197-1.2	G180I	Pathogenic	0.994
LRP5	O75197-1.2	G180K	Pathogenic	0.974
LRP5	O75197-1.2	G180L	Pathogenic	0.995
LRP5	O75197-1.2	G180M	Pathogenic	0.989
LRP5	O75197-1.2	G180N	Pathogenic	0.859
LRP5	O75197-1.2	G180P	Pathogenic	0.981
LRP5	O75197-1.2	G180Q	Pathogenic	0.987
LRP5	O75197-1.2	G180R	Pathogenic	0.973
LRP5	O75197-1.2	G180S	Pathogenic	0.913
LRP5	O75197-1.2	G180T	Pathogenic	0.987
LRP5	O75197-1.2	G180V	Pathogenic	0.99
LRP5	O75197-1.2	G180W	Pathogenic	0.921
LRP5	O75197-1.2	G180Y	Pathogenic	0.991
LRP5	O75197-1.2	M181A	Pathogenic	0.997
LRP5	O75197-1.2	M181C	Pathogenic	0.998
LRP5	O75197-1.2	M181D	Pathogenic	0.999
LRP5	O75197-1.2	M181E	Pathogenic	0.998
LRP5	O75197-1.2	M181F	Pathogenic	0.994
LRP5	O75197-1.2	M181G	Pathogenic	1.0
LRP5	O75197-1.2	M181H	Pathogenic	0.999
LRP5	O75197-1.2	M181I	Pathogenic	0.982
LRP5	O75197-1.2	M181K	Pathogenic	0.991
LRP5	O75197-1.2	M181L	Pathogenic	0.951
LRP5	O75197-1.2	M181N	Pathogenic	0.998
LRP5	O75197-1.2	M181P	Pathogenic	0.999
LRP5	O75197-1.2	M181Q	Pathogenic	0.987
LRP5	O75197-1.2	M181R	Pathogenic	0.991
LRP5	O75197-1.2	M181S	Pathogenic	0.996
LRP5	O75197-1.2	M181T	Pathogenic	0.997
LRP5	O75197-1.2	M181V	Pathogenic	0.988
LRP5	O75197-1.2	M181W	Pathogenic	0.997
LRP5	O75197-1.2	M181Y	Pathogenic	0.998
LRP5	O75197-1.2	D182A	Pathogenic	0.984
LRP5	O75197-1.2	D182C	Pathogenic	0.991
LRP5	O75197-1.2	D182E	Pathogenic	0.631
LRP5	O75197-1.2	D182F	Pathogenic	0.98
LRP5	O75197-1.2	D182G	Pathogenic	0.963
LRP5	O75197-1.2	D182H	Pathogenic	0.96
LRP5	O75197-1.2	D182I	Pathogenic	0.98
LRP5	O75197-1.2	D182K	Pathogenic	0.977
LRP5	O75197-1.2	D182L	Pathogenic	0.994
LRP5	O75197-1.2	D182M	Pathogenic	0.988
LRP5	O75197-1.2	D182N	Pathogenic	0.837
LRP5	O75197-1.2	D182P	Pathogenic	0.936
LRP5	O75197-1.2	D182Q	Pathogenic	0.915
LRP5	O75197-1.2	D182R	Pathogenic	0.992
LRP5	O75197-1.2	D182S	Pathogenic	0.902
LRP5	O75197-1.2	D182T	Pathogenic	0.957
LRP5	O75197-1.2	D182V	Pathogenic	0.988
LRP5	O75197-1.2	D182W	Pathogenic	0.989
LRP5	O75197-1.2	D182Y	Pathogenic	0.99
LRP5	O75197-1.2	G183A	Pathogenic	0.928
LRP5	O75197-1.2	G183C	Pathogenic	0.995
LRP5	O75197-1.2	G183D	Pathogenic	0.962
LRP5	O75197-1.2	G183E	Pathogenic	0.988
LRP5	O75197-1.2	G183F	Pathogenic	0.989
LRP5	O75197-1.2	G183H	Pathogenic	0.992
LRP5	O75197-1.2	G183I	Pathogenic	0.996
LRP5	O75197-1.2	G183K	Pathogenic	0.983
LRP5	O75197-1.2	G183L	Pathogenic	0.997
LRP5	O75197-1.2	G183M	Pathogenic	0.993
LRP5	O75197-1.2	G183N	Pathogenic	0.905
LRP5	O75197-1.2	G183P	Pathogenic	0.988
LRP5	O75197-1.2	G183Q	Pathogenic	0.992
LRP5	O75197-1.2	G183R	Pathogenic	0.983
LRP5	O75197-1.2	G183S	Pathogenic	0.942
LRP5	O75197-1.2	G183T	Pathogenic	0.992
LRP5	O75197-1.2	G183V	Pathogenic	0.993
LRP5	O75197-1.2	G183W	Pathogenic	0.948
LRP5	O75197-1.2	G183Y	Pathogenic	0.995
LRP5	O75197-1.2	S184A	Neutral	0.346
LRP5	O75197-1.2	S184C	Pathogenic	0.726
LRP5	O75197-1.2	S184D	Pathogenic	0.528
LRP5	O75197-1.2	S184E	Pathogenic	0.55
LRP5	O75197-1.2	S184F	Pathogenic	0.784
LRP5	O75197-1.2	S184G	Pathogenic	0.673
LRP5	O75197-1.2	S184H	Pathogenic	0.844
LRP5	O75197-1.2	S184I	Pathogenic	0.785
LRP5	O75197-1.2	S184K	Neutral	0.461
LRP5	O75197-1.2	S184L	Pathogenic	0.8
LRP5	O75197-1.2	S184M	Pathogenic	0.666
LRP5	O75197-1.2	S184N	Neutral	0.297
LRP5	O75197-1.2	S184P	Pathogenic	0.769
LRP5	O75197-1.2	S184Q	Pathogenic	0.638
LRP5	O75197-1.2	S184R	Pathogenic	0.715
LRP5	O75197-1.2	S184T	Neutral	0.352
LRP5	O75197-1.2	S184V	Pathogenic	0.864
LRP5	O75197-1.2	S184W	Pathogenic	0.875
LRP5	O75197-1.2	S184Y	Pathogenic	0.883
LRP5	O75197-1.2	T185A	Neutral	0.034
LRP5	O75197-1.2	T185C	Neutral	0.056
LRP5	O75197-1.2	T185D	Neutral	0.044
LRP5	O75197-1.2	T185E	Neutral	0.048
LRP5	O75197-1.2	T185F	Neutral	0.077
LRP5	O75197-1.2	T185G	Neutral	0.207
LRP5	O75197-1.2	T185H	Neutral	0.233
LRP5	O75197-1.2	T185I	Neutral	0.027
LRP5	O75197-1.2	T185K	Neutral	0.034
LRP5	O75197-1.2	T185L	Neutral	0.029
LRP5	O75197-1.2	T185M	Neutral	0.044
LRP5	O75197-1.2	T185N	Neutral	0.017
LRP5	O75197-1.2	T185P	Neutral	0.071
LRP5	O75197-1.2	T185Q	Neutral	0.068
LRP5	O75197-1.2	T185R	Neutral	0.033
LRP5	O75197-1.2	T185S	Neutral	0.009
LRP5	O75197-1.2	T185V	Neutral	0.016
LRP5	O75197-1.2	T185W	Neutral	0.05
LRP5	O75197-1.2	T185Y	Neutral	0.148
LRP5	O75197-1.2	R186A	Pathogenic	0.982
LRP5	O75197-1.2	R186C	Pathogenic	0.996
LRP5	O75197-1.2	R186D	Pathogenic	0.998
LRP5	O75197-1.2	R186E	Pathogenic	0.978
LRP5	O75197-1.2	R186F	Pathogenic	0.993
LRP5	O75197-1.2	R186G	Pathogenic	0.995
LRP5	O75197-1.2	R186H	Pathogenic	0.958
LRP5	O75197-1.2	R186I	Pathogenic	0.993
LRP5	O75197-1.2	R186K	Pathogenic	0.873
LRP5	O75197-1.2	R186L	Pathogenic	0.981
LRP5	O75197-1.2	R186M	Pathogenic	0.963
LRP5	O75197-1.2	R186N	Pathogenic	0.977
LRP5	O75197-1.2	R186P	Pathogenic	0.992
LRP5	O75197-1.2	R186Q	Pathogenic	0.911
LRP5	O75197-1.2	R186S	Pathogenic	0.987
LRP5	O75197-1.2	R186T	Pathogenic	0.983
LRP5	O75197-1.2	R186V	Pathogenic	0.996
LRP5	O75197-1.2	R186W	Pathogenic	0.99
LRP5	O75197-1.2	R186Y	Pathogenic	0.99
LRP5	O75197-1.2	K187A	Neutral	0.044
LRP5	O75197-1.2	K187C	Neutral	0.195
LRP5	O75197-1.2	K187D	Neutral	0.112
LRP5	O75197-1.2	K187E	Neutral	0.012
LRP5	O75197-1.2	K187F	Neutral	0.113
LRP5	O75197-1.2	K187G	Neutral	0.153
LRP5	O75197-1.2	K187H	Neutral	0.056
LRP5	O75197-1.2	K187I	Neutral	0.11
LRP5	O75197-1.2	K187L	Neutral	0.043
LRP5	O75197-1.2	K187M	Neutral	0.022
LRP5	O75197-1.2	K187N	Neutral	0.035
LRP5	O75197-1.2	K187P	Neutral	0.032
LRP5	O75197-1.2	K187Q	Neutral	0.009
LRP5	O75197-1.2	K187R	Neutral	0.006
LRP5	O75197-1.2	K187S	Neutral	0.021
LRP5	O75197-1.2	K187T	Neutral	0.048
LRP5	O75197-1.2	K187V	Neutral	0.062
LRP5	O75197-1.2	K187W	Neutral	0.075
LRP5	O75197-1.2	K187Y	Neutral	0.08
LRP5	O75197-1.2	I188A	Neutral	0.45
LRP5	O75197-1.2	I188C	Pathogenic	0.607
LRP5	O75197-1.2	I188D	Pathogenic	0.75
LRP5	O75197-1.2	I188E	Pathogenic	0.777
LRP5	O75197-1.2	I188F	Pathogenic	0.521
LRP5	O75197-1.2	I188G	Pathogenic	0.944
LRP5	O75197-1.2	I188H	Pathogenic	0.875
LRP5	O75197-1.2	I188K	Pathogenic	0.719
LRP5	O75197-1.2	I188L	Neutral	0.1
LRP5	O75197-1.2	I188M	Neutral	0.181
LRP5	O75197-1.2	I188N	Pathogenic	0.779
LRP5	O75197-1.2	I188P	Pathogenic	0.919
LRP5	O75197-1.2	I188Q	Pathogenic	0.836
LRP5	O75197-1.2	I188R	Pathogenic	0.712
LRP5	O75197-1.2	I188S	Pathogenic	0.649
LRP5	O75197-1.2	I188T	Neutral	0.449
LRP5	O75197-1.2	I188V	Neutral	0.022
LRP5	O75197-1.2	I188W	Pathogenic	0.952
LRP5	O75197-1.2	I188Y	Pathogenic	0.61
LRP5	O75197-1.2	I189A	Pathogenic	0.956
LRP5	O75197-1.2	I189C	Pathogenic	0.976
LRP5	O75197-1.2	I189D	Pathogenic	0.988
LRP5	O75197-1.2	I189E	Pathogenic	0.989
LRP5	O75197-1.2	I189F	Pathogenic	0.967
LRP5	O75197-1.2	I189G	Pathogenic	0.998
LRP5	O75197-1.2	I189H	Pathogenic	0.995
LRP5	O75197-1.2	I189K	Pathogenic	0.986
LRP5	O75197-1.2	I189L	Pathogenic	0.747
LRP5	O75197-1.2	I189M	Pathogenic	0.855
LRP5	O75197-1.2	I189N	Pathogenic	0.989
LRP5	O75197-1.2	I189P	Pathogenic	0.997
LRP5	O75197-1.2	I189Q	Pathogenic	0.993
LRP5	O75197-1.2	I189R	Pathogenic	0.985
LRP5	O75197-1.2	I189S	Pathogenic	0.98
LRP5	O75197-1.2	I189T	Pathogenic	0.956
LRP5	O75197-1.2	I189V	Neutral	0.38
LRP5	O75197-1.2	I189W	Pathogenic	0.998
LRP5	O75197-1.2	I189Y	Pathogenic	0.977
LRP5	O75197-1.2	V190A	Pathogenic	0.674
LRP5	O75197-1.2	V190C	Pathogenic	0.922
LRP5	O75197-1.2	V190D	Pathogenic	0.958
LRP5	O75197-1.2	V190E	Pathogenic	0.897
LRP5	O75197-1.2	V190F	Pathogenic	0.896
LRP5	O75197-1.2	V190G	Pathogenic	0.977
LRP5	O75197-1.2	V190H	Pathogenic	0.981
LRP5	O75197-1.2	V190I	Neutral	0.092
LRP5	O75197-1.2	V190K	Pathogenic	0.859
LRP5	O75197-1.2	V190L	Pathogenic	0.506
LRP5	O75197-1.2	V190M	Pathogenic	0.609
LRP5	O75197-1.2	V190N	Pathogenic	0.964
LRP5	O75197-1.2	V190P	Pathogenic	0.966
LRP5	O75197-1.2	V190Q	Pathogenic	0.926
LRP5	O75197-1.2	V190R	Pathogenic	0.947
LRP5	O75197-1.2	V190S	Pathogenic	0.934
LRP5	O75197-1.2	V190T	Pathogenic	0.673
LRP5	O75197-1.2	V190W	Pathogenic	0.981
LRP5	O75197-1.2	V190Y	Pathogenic	0.919
LRP5	O75197-1.2	D191A	Neutral	0.159
LRP5	O75197-1.2	D191C	Neutral	0.245
LRP5	O75197-1.2	D191E	Neutral	0.005
LRP5	O75197-1.2	D191F	Neutral	0.129
LRP5	O75197-1.2	D191G	Neutral	0.074
LRP5	O75197-1.2	D191H	Neutral	0.068
LRP5	O75197-1.2	D191I	Neutral	0.13
LRP5	O75197-1.2	D191K	Neutral	0.115
LRP5	O75197-1.2	D191L	Neutral	0.332
LRP5	O75197-1.2	D191M	Neutral	0.199
LRP5	O75197-1.2	D191N	Neutral	0.015
LRP5	O75197-1.2	D191P	Neutral	0.043
LRP5	O75197-1.2	D191Q	Neutral	0.032
LRP5	O75197-1.2	D191R	Neutral	0.276
LRP5	O75197-1.2	D191S	Neutral	0.027
LRP5	O75197-1.2	D191T	Neutral	0.063
LRP5	O75197-1.2	D191V	Neutral	0.206
LRP5	O75197-1.2	D191W	Neutral	0.222
LRP5	O75197-1.2	D191Y	Neutral	0.235
LRP5	O75197-1.2	S192A	Neutral	0.004
LRP5	O75197-1.2	S192C	Neutral	0.018
LRP5	O75197-1.2	S192D	Neutral	0.008
LRP5	O75197-1.2	S192E	Neutral	0.009
LRP5	O75197-1.2	S192F	Neutral	0.025
LRP5	O75197-1.2	S192G	Neutral	0.014
LRP5	O75197-1.2	S192H	Neutral	0.037
LRP5	O75197-1.2	S192I	Neutral	0.025
LRP5	O75197-1.2	S192K	Neutral	0.006
LRP5	O75197-1.2	S192L	Neutral	0.027
LRP5	O75197-1.2	S192M	Neutral	0.014
LRP5	O75197-1.2	S192N	Neutral	0.003
LRP5	O75197-1.2	S192P	Neutral	0.023
LRP5	O75197-1.2	S192Q	Neutral	0.012
LRP5	O75197-1.2	S192R	Neutral	0.017
LRP5	O75197-1.2	S192T	Neutral	0.004
LRP5	O75197-1.2	S192V	Neutral	0.043
LRP5	O75197-1.2	S192W	Neutral	0.047
LRP5	O75197-1.2	S192Y	Neutral	0.051
LRP5	O75197-1.2	D193A	Pathogenic	0.728
LRP5	O75197-1.2	D193C	Pathogenic	0.821
LRP5	O75197-1.2	D193E	Neutral	0.069
LRP5	O75197-1.2	D193F	Pathogenic	0.678
LRP5	O75197-1.2	D193G	Pathogenic	0.53
LRP5	O75197-1.2	D193H	Pathogenic	0.507
LRP5	O75197-1.2	D193I	Pathogenic	0.679
LRP5	O75197-1.2	D193K	Pathogenic	0.648
LRP5	O75197-1.2	D193L	Pathogenic	0.876
LRP5	O75197-1.2	D193M	Pathogenic	0.779
LRP5	O75197-1.2	D193N	Neutral	0.181
LRP5	O75197-1.2	D193P	Neutral	0.388
LRP5	O75197-1.2	D193Q	Neutral	0.317
LRP5	O75197-1.2	D193R	Pathogenic	0.844
LRP5	O75197-1.2	D193S	Neutral	0.285
LRP5	O75197-1.2	D193T	Neutral	0.489
LRP5	O75197-1.2	D193V	Pathogenic	0.786
LRP5	O75197-1.2	D193W	Pathogenic	0.802
LRP5	O75197-1.2	D193Y	Pathogenic	0.814
LRP5	O75197-1.2	I194A	Pathogenic	0.981
LRP5	O75197-1.2	I194C	Pathogenic	0.99
LRP5	O75197-1.2	I194D	Pathogenic	0.995
LRP5	O75197-1.2	I194E	Pathogenic	0.996
LRP5	O75197-1.2	I194F	Pathogenic	0.986
LRP5	O75197-1.2	I194G	Pathogenic	0.999
LRP5	O75197-1.2	I194H	Pathogenic	0.998
LRP5	O75197-1.2	I194K	Pathogenic	0.994
LRP5	O75197-1.2	I194L	Pathogenic	0.876
LRP5	O75197-1.2	I194M	Pathogenic	0.934
LRP5	O75197-1.2	I194N	Pathogenic	0.996
LRP5	O75197-1.2	I194P	Pathogenic	0.999
LRP5	O75197-1.2	I194Q	Pathogenic	0.997
LRP5	O75197-1.2	I194R	Pathogenic	0.994
LRP5	O75197-1.2	I194S	Pathogenic	0.992
LRP5	O75197-1.2	I194T	Pathogenic	0.981
LRP5	O75197-1.2	I194V	Pathogenic	0.594
LRP5	O75197-1.2	I194W	Pathogenic	0.999
LRP5	O75197-1.2	I194Y	Pathogenic	0.99
LRP5	O75197-1.2	Y195A	Pathogenic	0.982
LRP5	O75197-1.2	Y195C	Pathogenic	0.99
LRP5	O75197-1.2	Y195D	Pathogenic	0.985
LRP5	O75197-1.2	Y195E	Pathogenic	0.962
LRP5	O75197-1.2	Y195F	Neutral	0.167
LRP5	O75197-1.2	Y195G	Pathogenic	0.992
LRP5	O75197-1.2	Y195H	Neutral	0.373
LRP5	O75197-1.2	Y195I	Pathogenic	0.943
LRP5	O75197-1.2	Y195K	Pathogenic	0.95
LRP5	O75197-1.2	Y195L	Pathogenic	0.948
LRP5	O75197-1.2	Y195M	Pathogenic	0.965
LRP5	O75197-1.2	Y195N	Pathogenic	0.962
LRP5	O75197-1.2	Y195P	Pathogenic	0.996
LRP5	O75197-1.2	Y195Q	Pathogenic	0.924
LRP5	O75197-1.2	Y195R	Pathogenic	0.95
LRP5	O75197-1.2	Y195S	Pathogenic	0.976
LRP5	O75197-1.2	Y195T	Pathogenic	0.982
LRP5	O75197-1.2	Y195V	Pathogenic	0.965
LRP5	O75197-1.2	Y195W	Neutral	0.283
LRP5	O75197-1.2	W196A	Pathogenic	0.999
LRP5	O75197-1.2	W196C	Pathogenic	0.999
LRP5	O75197-1.2	W196D	Pathogenic	0.999
LRP5	O75197-1.2	W196E	Pathogenic	0.998
LRP5	O75197-1.2	W196F	Pathogenic	0.982
LRP5	O75197-1.2	W196G	Pathogenic	0.996
LRP5	O75197-1.2	W196H	Pathogenic	0.997
LRP5	O75197-1.2	W196I	Pathogenic	1.0
LRP5	O75197-1.2	W196K	Pathogenic	0.997
LRP5	O75197-1.2	W196L	Pathogenic	0.999
LRP5	O75197-1.2	W196M	Pathogenic	0.997
LRP5	O75197-1.2	W196N	Pathogenic	0.999
LRP5	O75197-1.2	W196P	Pathogenic	1.0
LRP5	O75197-1.2	W196Q	Pathogenic	0.996
LRP5	O75197-1.2	W196R	Pathogenic	0.997
LRP5	O75197-1.2	W196S	Pathogenic	0.999
LRP5	O75197-1.2	W196T	Pathogenic	0.997
LRP5	O75197-1.2	W196V	Pathogenic	1.0
LRP5	O75197-1.2	W196Y	Pathogenic	0.896
LRP5	O75197-1.2	P197A	Pathogenic	0.993
LRP5	O75197-1.2	P197C	Pathogenic	0.999
LRP5	O75197-1.2	P197D	Pathogenic	0.984
LRP5	O75197-1.2	P197E	Pathogenic	0.985
LRP5	O75197-1.2	P197F	Pathogenic	1.0
LRP5	O75197-1.2	P197G	Pathogenic	0.997
LRP5	O75197-1.2	P197H	Pathogenic	0.997
LRP5	O75197-1.2	P197I	Pathogenic	0.999
LRP5	O75197-1.2	P197K	Pathogenic	0.979
LRP5	O75197-1.2	P197L	Pathogenic	0.999
LRP5	O75197-1.2	P197M	Pathogenic	0.998
LRP5	O75197-1.2	P197N	Pathogenic	0.995
LRP5	O75197-1.2	P197Q	Pathogenic	0.989
LRP5	O75197-1.2	P197R	Pathogenic	0.993
LRP5	O75197-1.2	P197S	Pathogenic	0.991
LRP5	O75197-1.2	P197T	Pathogenic	0.993
LRP5	O75197-1.2	P197V	Pathogenic	0.998
LRP5	O75197-1.2	P197W	Pathogenic	0.999
LRP5	O75197-1.2	P197Y	Pathogenic	0.999
LRP5	O75197-1.2	N198A	Pathogenic	0.998
LRP5	O75197-1.2	N198C	Pathogenic	0.999
LRP5	O75197-1.2	N198D	Pathogenic	0.969
LRP5	O75197-1.2	N198E	Pathogenic	0.991
LRP5	O75197-1.2	N198F	Pathogenic	0.997
LRP5	O75197-1.2	N198G	Pathogenic	0.984
LRP5	O75197-1.2	N198H	Pathogenic	0.948
LRP5	O75197-1.2	N198I	Pathogenic	0.997
LRP5	O75197-1.2	N198K	Pathogenic	0.987
LRP5	O75197-1.2	N198L	Pathogenic	0.997
LRP5	O75197-1.2	N198M	Pathogenic	0.995
LRP5	O75197-1.2	N198P	Pathogenic	0.997
LRP5	O75197-1.2	N198Q	Pathogenic	0.987
LRP5	O75197-1.2	N198R	Pathogenic	0.986
LRP5	O75197-1.2	N198S	Pathogenic	0.955
LRP5	O75197-1.2	N198T	Pathogenic	0.981
LRP5	O75197-1.2	N198V	Pathogenic	0.998
LRP5	O75197-1.2	N198W	Pathogenic	0.999
LRP5	O75197-1.2	N198Y	Pathogenic	0.996
LRP5	O75197-1.2	G199A	Pathogenic	0.978
LRP5	O75197-1.2	G199C	Pathogenic	0.999
LRP5	O75197-1.2	G199D	Pathogenic	0.989
LRP5	O75197-1.2	G199E	Pathogenic	0.997
LRP5	O75197-1.2	G199F	Pathogenic	0.997
LRP5	O75197-1.2	G199H	Pathogenic	0.998
LRP5	O75197-1.2	G199I	Pathogenic	0.999
LRP5	O75197-1.2	G199K	Pathogenic	0.995
LRP5	O75197-1.2	G199L	Pathogenic	0.999
LRP5	O75197-1.2	G199M	Pathogenic	0.998
LRP5	O75197-1.2	G199N	Pathogenic	0.971
LRP5	O75197-1.2	G199P	Pathogenic	0.996
LRP5	O75197-1.2	G199Q	Pathogenic	0.998
LRP5	O75197-1.2	G199R	Pathogenic	0.995
LRP5	O75197-1.2	G199S	Pathogenic	0.983
LRP5	O75197-1.2	G199T	Pathogenic	0.998
LRP5	O75197-1.2	G199V	Pathogenic	0.998
LRP5	O75197-1.2	G199W	Pathogenic	0.984
LRP5	O75197-1.2	G199Y	Pathogenic	0.998
LRP5	O75197-1.2	L200A	Pathogenic	0.974
LRP5	O75197-1.2	L200C	Pathogenic	0.986
LRP5	O75197-1.2	L200D	Pathogenic	0.998
LRP5	O75197-1.2	L200E	Pathogenic	0.994
LRP5	O75197-1.2	L200F	Pathogenic	0.977
LRP5	O75197-1.2	L200G	Pathogenic	0.999
LRP5	O75197-1.2	L200H	Pathogenic	0.997
LRP5	O75197-1.2	L200I	Pathogenic	0.824
LRP5	O75197-1.2	L200K	Pathogenic	0.975
LRP5	O75197-1.2	L200M	Pathogenic	0.771
LRP5	O75197-1.2	L200N	Pathogenic	0.994
LRP5	O75197-1.2	L200P	Pathogenic	0.998
LRP5	O75197-1.2	L200Q	Pathogenic	0.987
LRP5	O75197-1.2	L200R	Pathogenic	0.974
LRP5	O75197-1.2	L200S	Pathogenic	0.988
LRP5	O75197-1.2	L200T	Pathogenic	0.974
LRP5	O75197-1.2	L200V	Pathogenic	0.907
LRP5	O75197-1.2	L200W	Pathogenic	0.996
LRP5	O75197-1.2	L200Y	Pathogenic	0.986
LRP5	O75197-1.2	T201A	Pathogenic	0.984
LRP5	O75197-1.2	T201C	Pathogenic	0.99
LRP5	O75197-1.2	T201D	Pathogenic	0.988
LRP5	O75197-1.2	T201E	Pathogenic	0.989
LRP5	O75197-1.2	T201F	Pathogenic	0.993
LRP5	O75197-1.2	T201G	Pathogenic	0.998
LRP5	O75197-1.2	T201H	Pathogenic	0.998
LRP5	O75197-1.2	T201I	Pathogenic	0.98
LRP5	O75197-1.2	T201K	Pathogenic	0.984
LRP5	O75197-1.2	T201L	Pathogenic	0.981
LRP5	O75197-1.2	T201M	Pathogenic	0.988
LRP5	O75197-1.2	T201N	Pathogenic	0.968
LRP5	O75197-1.2	T201P	Pathogenic	0.993
LRP5	O75197-1.2	T201Q	Pathogenic	0.992
LRP5	O75197-1.2	T201R	Pathogenic	0.984
LRP5	O75197-1.2	T201S	Pathogenic	0.942
LRP5	O75197-1.2	T201V	Pathogenic	0.965
LRP5	O75197-1.2	T201W	Pathogenic	0.989
LRP5	O75197-1.2	T201Y	Pathogenic	0.997
LRP5	O75197-1.2	I202A	Neutral	0.343
LRP5	O75197-1.2	I202C	Neutral	0.496
LRP5	O75197-1.2	I202D	Pathogenic	0.657
LRP5	O75197-1.2	I202E	Pathogenic	0.689
LRP5	O75197-1.2	I202F	Neutral	0.41
LRP5	O75197-1.2	I202G	Pathogenic	0.915
LRP5	O75197-1.2	I202H	Pathogenic	0.817
LRP5	O75197-1.2	I202K	Pathogenic	0.62
LRP5	O75197-1.2	I202L	Neutral	0.066
LRP5	O75197-1.2	I202M	Neutral	0.124
LRP5	O75197-1.2	I202N	Pathogenic	0.692
LRP5	O75197-1.2	I202P	Pathogenic	0.879
LRP5	O75197-1.2	I202Q	Pathogenic	0.765
LRP5	O75197-1.2	I202R	Pathogenic	0.612
LRP5	O75197-1.2	I202S	Pathogenic	0.541
LRP5	O75197-1.2	I202T	Neutral	0.342
LRP5	O75197-1.2	I202V	Neutral	0.014
LRP5	O75197-1.2	I202W	Pathogenic	0.927
LRP5	O75197-1.2	I202Y	Neutral	0.499
LRP5	O75197-1.2	D203A	Pathogenic	0.994
LRP5	O75197-1.2	D203C	Pathogenic	0.997
LRP5	O75197-1.2	D203E	Pathogenic	0.828
LRP5	O75197-1.2	D203F	Pathogenic	0.993
LRP5	O75197-1.2	D203G	Pathogenic	0.987
LRP5	O75197-1.2	D203H	Pathogenic	0.985
LRP5	O75197-1.2	D203I	Pathogenic	0.993
LRP5	O75197-1.2	D203K	Pathogenic	0.992
LRP5	O75197-1.2	D203L	Pathogenic	0.998
LRP5	O75197-1.2	D203M	Pathogenic	0.996
LRP5	O75197-1.2	D203N	Pathogenic	0.935
LRP5	O75197-1.2	D203P	Pathogenic	0.976
LRP5	O75197-1.2	D203Q	Pathogenic	0.968
LRP5	O75197-1.2	D203R	Pathogenic	0.997
LRP5	O75197-1.2	D203S	Pathogenic	0.963
LRP5	O75197-1.2	D203T	Pathogenic	0.984
LRP5	O75197-1.2	D203V	Pathogenic	0.996
LRP5	O75197-1.2	D203W	Pathogenic	0.996
LRP5	O75197-1.2	D203Y	Pathogenic	0.997
LRP5	O75197-1.2	L204A	Neutral	0.276
LRP5	O75197-1.2	L204C	Neutral	0.418
LRP5	O75197-1.2	L204D	Pathogenic	0.81
LRP5	O75197-1.2	L204E	Pathogenic	0.619
LRP5	O75197-1.2	L204F	Neutral	0.303
LRP5	O75197-1.2	L204G	Pathogenic	0.888
LRP5	O75197-1.2	L204H	Pathogenic	0.766
LRP5	O75197-1.2	L204I	Neutral	0.045
LRP5	O75197-1.2	L204K	Neutral	0.282
LRP5	O75197-1.2	L204M	Neutral	0.033
LRP5	O75197-1.2	L204N	Pathogenic	0.622
LRP5	O75197-1.2	L204P	Pathogenic	0.841
LRP5	O75197-1.2	L204Q	Neutral	0.439
LRP5	O75197-1.2	L204R	Neutral	0.275
LRP5	O75197-1.2	L204S	Neutral	0.463
LRP5	O75197-1.2	L204T	Neutral	0.276
LRP5	O75197-1.2	L204V	Neutral	0.09
LRP5	O75197-1.2	L204W	Pathogenic	0.718
LRP5	O75197-1.2	L204Y	Neutral	0.422
LRP5	O75197-1.2	E205A	Neutral	0.199
LRP5	O75197-1.2	E205C	Pathogenic	0.797
LRP5	O75197-1.2	E205D	Neutral	0.019
LRP5	O75197-1.2	E205F	Neutral	0.385
LRP5	O75197-1.2	E205G	Neutral	0.491
LRP5	O75197-1.2	E205H	Neutral	0.091
LRP5	O75197-1.2	E205I	Neutral	0.386
LRP5	O75197-1.2	E205K	Neutral	0.045
LRP5	O75197-1.2	E205L	Neutral	0.408
LRP5	O75197-1.2	E205M	Neutral	0.256
LRP5	O75197-1.2	E205N	Neutral	0.161
LRP5	O75197-1.2	E205P	Neutral	0.151
LRP5	O75197-1.2	E205Q	Neutral	0.015
LRP5	O75197-1.2	E205R	Neutral	0.121
LRP5	O75197-1.2	E205S	Neutral	0.101
LRP5	O75197-1.2	E205T	Neutral	0.213
LRP5	O75197-1.2	E205V	Neutral	0.262
LRP5	O75197-1.2	E205W	Neutral	0.284
LRP5	O75197-1.2	E205Y	Neutral	0.299
LRP5	O75197-1.2	E206A	Pathogenic	0.702
LRP5	O75197-1.2	E206C	Pathogenic	0.974
LRP5	O75197-1.2	E206D	Neutral	0.152
LRP5	O75197-1.2	E206F	Pathogenic	0.856
LRP5	O75197-1.2	E206G	Pathogenic	0.901
LRP5	O75197-1.2	E206H	Neutral	0.488
LRP5	O75197-1.2	E206I	Pathogenic	0.856
LRP5	O75197-1.2	E206K	Neutral	0.307
LRP5	O75197-1.2	E206L	Pathogenic	0.867
LRP5	O75197-1.2	E206M	Pathogenic	0.766
LRP5	O75197-1.2	E206N	Pathogenic	0.646
LRP5	O75197-1.2	E206P	Pathogenic	0.628
LRP5	O75197-1.2	E206Q	Neutral	0.124
LRP5	O75197-1.2	E206R	Pathogenic	0.566
LRP5	O75197-1.2	E206S	Pathogenic	0.515
LRP5	O75197-1.2	E206T	Pathogenic	0.72
LRP5	O75197-1.2	E206V	Pathogenic	0.771
LRP5	O75197-1.2	E206W	Pathogenic	0.79
LRP5	O75197-1.2	E206Y	Pathogenic	0.802
LRP5	O75197-1.2	Q207A	Pathogenic	0.609
LRP5	O75197-1.2	Q207C	Pathogenic	0.89
LRP5	O75197-1.2	Q207D	Neutral	0.343
LRP5	O75197-1.2	Q207E	Neutral	0.061
LRP5	O75197-1.2	Q207F	Pathogenic	0.8
LRP5	O75197-1.2	Q207G	Pathogenic	0.858
LRP5	O75197-1.2	Q207H	Neutral	0.391
LRP5	O75197-1.2	Q207I	Pathogenic	0.8
LRP5	O75197-1.2	Q207K	Neutral	0.124
LRP5	O75197-1.2	Q207L	Pathogenic	0.591
LRP5	O75197-1.2	Q207M	Neutral	0.192
LRP5	O75197-1.2	Q207N	Neutral	0.379
LRP5	O75197-1.2	Q207P	Pathogenic	0.528
LRP5	O75197-1.2	Q207R	Neutral	0.12
LRP5	O75197-1.2	Q207S	Neutral	0.413
LRP5	O75197-1.2	Q207T	Pathogenic	0.629
LRP5	O75197-1.2	Q207V	Pathogenic	0.69
LRP5	O75197-1.2	Q207W	Neutral	0.454
LRP5	O75197-1.2	Q207Y	Neutral	0.473
LRP5	O75197-1.2	K208A	Pathogenic	0.87
LRP5	O75197-1.2	K208C	Pathogenic	0.972
LRP5	O75197-1.2	K208D	Pathogenic	0.948
LRP5	O75197-1.2	K208E	Pathogenic	0.644
LRP5	O75197-1.2	K208F	Pathogenic	0.949
LRP5	O75197-1.2	K208G	Pathogenic	0.963
LRP5	O75197-1.2	K208H	Pathogenic	0.895
LRP5	O75197-1.2	K208I	Pathogenic	0.947
LRP5	O75197-1.2	K208L	Pathogenic	0.866
LRP5	O75197-1.2	K208M	Pathogenic	0.763
LRP5	O75197-1.2	K208N	Pathogenic	0.839
LRP5	O75197-1.2	K208P	Pathogenic	0.828
LRP5	O75197-1.2	K208Q	Pathogenic	0.556
LRP5	O75197-1.2	K208R	Neutral	0.451
LRP5	O75197-1.2	K208S	Pathogenic	0.752
LRP5	O75197-1.2	K208T	Pathogenic	0.88
LRP5	O75197-1.2	K208V	Pathogenic	0.906
LRP5	O75197-1.2	K208W	Pathogenic	0.921
LRP5	O75197-1.2	K208Y	Pathogenic	0.926
LRP5	O75197-1.2	L209A	Pathogenic	0.744
LRP5	O75197-1.2	L209C	Pathogenic	0.845
LRP5	O75197-1.2	L209D	Pathogenic	0.97
LRP5	O75197-1.2	L209E	Pathogenic	0.925
LRP5	O75197-1.2	L209F	Pathogenic	0.767
LRP5	O75197-1.2	L209G	Pathogenic	0.984
LRP5	O75197-1.2	L209H	Pathogenic	0.961
LRP5	O75197-1.2	L209I	Neutral	0.264
LRP5	O75197-1.2	L209K	Pathogenic	0.749
LRP5	O75197-1.2	L209M	Neutral	0.205
LRP5	O75197-1.2	L209N	Pathogenic	0.926
LRP5	O75197-1.2	L209P	Pathogenic	0.976
LRP5	O75197-1.2	L209Q	Pathogenic	0.856
LRP5	O75197-1.2	L209R	Pathogenic	0.742
LRP5	O75197-1.2	L209S	Pathogenic	0.868
LRP5	O75197-1.2	L209T	Pathogenic	0.743
LRP5	O75197-1.2	L209V	Neutral	0.429
LRP5	O75197-1.2	L209W	Pathogenic	0.951
LRP5	O75197-1.2	L209Y	Pathogenic	0.847
LRP5	O75197-1.2	Y210A	Pathogenic	0.996
LRP5	O75197-1.2	Y210C	Pathogenic	0.998
LRP5	O75197-1.2	Y210D	Pathogenic	0.997
LRP5	O75197-1.2	Y210E	Pathogenic	0.992
LRP5	O75197-1.2	Y210F	Neutral	0.492
LRP5	O75197-1.2	Y210G	Pathogenic	0.998
LRP5	O75197-1.2	Y210H	Pathogenic	0.742
LRP5	O75197-1.2	Y210I	Pathogenic	0.988
LRP5	O75197-1.2	Y210K	Pathogenic	0.989
LRP5	O75197-1.2	Y210L	Pathogenic	0.989
LRP5	O75197-1.2	Y210M	Pathogenic	0.993
LRP5	O75197-1.2	Y210N	Pathogenic	0.992
LRP5	O75197-1.2	Y210P	Pathogenic	0.999
LRP5	O75197-1.2	Y210Q	Pathogenic	0.983
LRP5	O75197-1.2	Y210R	Pathogenic	0.989
LRP5	O75197-1.2	Y210S	Pathogenic	0.995
LRP5	O75197-1.2	Y210T	Pathogenic	0.996
LRP5	O75197-1.2	Y210V	Pathogenic	0.992
LRP5	O75197-1.2	Y210W	Pathogenic	0.655
LRP5	O75197-1.2	W211A	Pathogenic	0.999
LRP5	O75197-1.2	W211C	Pathogenic	0.999
LRP5	O75197-1.2	W211D	Pathogenic	0.999
LRP5	O75197-1.2	W211E	Pathogenic	0.998
LRP5	O75197-1.2	W211F	Pathogenic	0.982
LRP5	O75197-1.2	W211G	Pathogenic	0.996
LRP5	O75197-1.2	W211H	Pathogenic	0.997
LRP5	O75197-1.2	W211I	Pathogenic	1.0
LRP5	O75197-1.2	W211K	Pathogenic	0.998
LRP5	O75197-1.2	W211L	Pathogenic	0.999
LRP5	O75197-1.2	W211M	Pathogenic	0.997
LRP5	O75197-1.2	W211N	Pathogenic	0.999
LRP5	O75197-1.2	W211P	Pathogenic	1.0
LRP5	O75197-1.2	W211Q	Pathogenic	0.996
LRP5	O75197-1.2	W211R	Pathogenic	0.998
LRP5	O75197-1.2	W211S	Pathogenic	0.999
LRP5	O75197-1.2	W211T	Pathogenic	0.997
LRP5	O75197-1.2	W211V	Pathogenic	1.0
LRP5	O75197-1.2	W211Y	Pathogenic	0.899
LRP5	O75197-1.2	A212C	Pathogenic	0.923
LRP5	O75197-1.2	A212D	Pathogenic	0.987
LRP5	O75197-1.2	A212E	Pathogenic	0.965
LRP5	O75197-1.2	A212F	Pathogenic	0.98
LRP5	O75197-1.2	A212G	Pathogenic	0.944
LRP5	O75197-1.2	A212H	Pathogenic	0.994
LRP5	O75197-1.2	A212I	Pathogenic	0.943
LRP5	O75197-1.2	A212K	Pathogenic	0.951
LRP5	O75197-1.2	A212L	Pathogenic	0.948
LRP5	O75197-1.2	A212M	Pathogenic	0.965
LRP5	O75197-1.2	A212N	Pathogenic	0.989
LRP5	O75197-1.2	A212P	Pathogenic	0.979
LRP5	O75197-1.2	A212Q	Pathogenic	0.976
LRP5	O75197-1.2	A212R	Pathogenic	0.949
LRP5	O75197-1.2	A212S	Pathogenic	0.845
LRP5	O75197-1.2	A212T	Pathogenic	0.954
LRP5	O75197-1.2	A212V	Pathogenic	0.905
LRP5	O75197-1.2	A212W	Pathogenic	0.99
LRP5	O75197-1.2	A212Y	Pathogenic	0.99
LRP5	O75197-1.2	D213A	Pathogenic	0.995
LRP5	O75197-1.2	D213C	Pathogenic	0.997
LRP5	O75197-1.2	D213E	Pathogenic	0.832
LRP5	O75197-1.2	D213F	Pathogenic	0.993
LRP5	O75197-1.2	D213G	Pathogenic	0.987
LRP5	O75197-1.2	D213H	Pathogenic	0.986
LRP5	O75197-1.2	D213I	Pathogenic	0.993
LRP5	O75197-1.2	D213K	Pathogenic	0.992
LRP5	O75197-1.2	D213L	Pathogenic	0.998
LRP5	O75197-1.2	D213M	Pathogenic	0.996
LRP5	O75197-1.2	D213N	Pathogenic	0.937
LRP5	O75197-1.2	D213P	Pathogenic	0.977
LRP5	O75197-1.2	D213Q	Pathogenic	0.969
LRP5	O75197-1.2	D213R	Pathogenic	0.997
LRP5	O75197-1.2	D213S	Pathogenic	0.964
LRP5	O75197-1.2	D213T	Pathogenic	0.985
LRP5	O75197-1.2	D213V	Pathogenic	0.996
LRP5	O75197-1.2	D213W	Pathogenic	0.996
LRP5	O75197-1.2	D213Y	Pathogenic	0.997
LRP5	O75197-1.2	A214C	Pathogenic	0.893
LRP5	O75197-1.2	A214D	Pathogenic	0.982
LRP5	O75197-1.2	A214E	Pathogenic	0.951
LRP5	O75197-1.2	A214F	Pathogenic	0.972
LRP5	O75197-1.2	A214G	Pathogenic	0.921
LRP5	O75197-1.2	A214H	Pathogenic	0.991
LRP5	O75197-1.2	A214I	Pathogenic	0.92
LRP5	O75197-1.2	A214K	Pathogenic	0.931
LRP5	O75197-1.2	A214L	Pathogenic	0.926
LRP5	O75197-1.2	A214M	Pathogenic	0.95
LRP5	O75197-1.2	A214N	Pathogenic	0.984
LRP5	O75197-1.2	A214P	Pathogenic	0.97
LRP5	O75197-1.2	A214Q	Pathogenic	0.965
LRP5	O75197-1.2	A214R	Pathogenic	0.929
LRP5	O75197-1.2	A214S	Pathogenic	0.79
LRP5	O75197-1.2	A214T	Pathogenic	0.935
LRP5	O75197-1.2	A214V	Pathogenic	0.868
LRP5	O75197-1.2	A214W	Pathogenic	0.985
LRP5	O75197-1.2	A214Y	Pathogenic	0.986
LRP5	O75197-1.2	K215A	Pathogenic	0.968
LRP5	O75197-1.2	K215C	Pathogenic	0.994
LRP5	O75197-1.2	K215D	Pathogenic	0.988
LRP5	O75197-1.2	K215E	Pathogenic	0.892
LRP5	O75197-1.2	K215F	Pathogenic	0.988
LRP5	O75197-1.2	K215G	Pathogenic	0.992
LRP5	O75197-1.2	K215H	Pathogenic	0.975
LRP5	O75197-1.2	K215I	Pathogenic	0.988
LRP5	O75197-1.2	K215L	Pathogenic	0.967
LRP5	O75197-1.2	K215M	Pathogenic	0.936
LRP5	O75197-1.2	K215N	Pathogenic	0.96
LRP5	O75197-1.2	K215P	Pathogenic	0.957
LRP5	O75197-1.2	K215Q	Pathogenic	0.851
LRP5	O75197-1.2	K215R	Pathogenic	0.789
LRP5	O75197-1.2	K215S	Pathogenic	0.933
LRP5	O75197-1.2	K215T	Pathogenic	0.971
LRP5	O75197-1.2	K215V	Pathogenic	0.978
LRP5	O75197-1.2	K215W	Pathogenic	0.982
LRP5	O75197-1.2	K215Y	Pathogenic	0.983
LRP5	O75197-1.2	L216A	Pathogenic	0.857
LRP5	O75197-1.2	L216C	Pathogenic	0.918
LRP5	O75197-1.2	L216D	Pathogenic	0.985
LRP5	O75197-1.2	L216E	Pathogenic	0.962
LRP5	O75197-1.2	L216F	Pathogenic	0.872
LRP5	O75197-1.2	L216G	Pathogenic	0.992
LRP5	O75197-1.2	L216H	Pathogenic	0.981
LRP5	O75197-1.2	L216I	Neutral	0.424
LRP5	O75197-1.2	L216K	Pathogenic	0.86
LRP5	O75197-1.2	L216M	Neutral	0.347
LRP5	O75197-1.2	L216N	Pathogenic	0.963
LRP5	O75197-1.2	L216P	Pathogenic	0.988
LRP5	O75197-1.2	L216Q	Pathogenic	0.924
LRP5	O75197-1.2	L216R	Pathogenic	0.856
LRP5	O75197-1.2	L216S	Pathogenic	0.931
LRP5	O75197-1.2	L216T	Pathogenic	0.856
LRP5	O75197-1.2	L216V	Pathogenic	0.607
LRP5	O75197-1.2	L216W	Pathogenic	0.975
LRP5	O75197-1.2	L216Y	Pathogenic	0.919
LRP5	O75197-1.2	S217A	Neutral	0.049
LRP5	O75197-1.2	S217C	Neutral	0.204
LRP5	O75197-1.2	S217D	Neutral	0.097
LRP5	O75197-1.2	S217E	Neutral	0.106
LRP5	O75197-1.2	S217F	Neutral	0.259
LRP5	O75197-1.2	S217G	Neutral	0.166
LRP5	O75197-1.2	S217H	Neutral	0.342
LRP5	O75197-1.2	S217I	Neutral	0.26
LRP5	O75197-1.2	S217K	Neutral	0.076
LRP5	O75197-1.2	S217L	Neutral	0.278
LRP5	O75197-1.2	S217M	Neutral	0.162
LRP5	O75197-1.2	S217N	Neutral	0.039
LRP5	O75197-1.2	S217P	Neutral	0.244
LRP5	O75197-1.2	S217Q	Neutral	0.145
LRP5	O75197-1.2	S217R	Neutral	0.195
LRP5	O75197-1.2	S217T	Neutral	0.05
LRP5	O75197-1.2	S217V	Neutral	0.38
LRP5	O75197-1.2	S217W	Neutral	0.403
LRP5	O75197-1.2	S217Y	Neutral	0.421
LRP5	O75197-1.2	F218A	Pathogenic	0.98
LRP5	O75197-1.2	F218C	Pathogenic	0.989
LRP5	O75197-1.2	F218D	Pathogenic	0.984
LRP5	O75197-1.2	F218E	Pathogenic	0.986
LRP5	O75197-1.2	F218G	Pathogenic	0.991
LRP5	O75197-1.2	F218H	Pathogenic	0.938
LRP5	O75197-1.2	F218I	Pathogenic	0.956
LRP5	O75197-1.2	F218K	Pathogenic	0.981
LRP5	O75197-1.2	F218L	Pathogenic	0.953
LRP5	O75197-1.2	F218M	Pathogenic	0.931
LRP5	O75197-1.2	F218N	Pathogenic	0.986
LRP5	O75197-1.2	F218P	Pathogenic	0.999
LRP5	O75197-1.2	F218Q	Pathogenic	0.99
LRP5	O75197-1.2	F218R	Pathogenic	0.981
LRP5	O75197-1.2	F218S	Pathogenic	0.974
LRP5	O75197-1.2	F218T	Pathogenic	0.98
LRP5	O75197-1.2	F218V	Pathogenic	0.975
LRP5	O75197-1.2	F218W	Pathogenic	0.824
LRP5	O75197-1.2	F218Y	Neutral	0.274
LRP5	O75197-1.2	I219A	Pathogenic	0.981
LRP5	O75197-1.2	I219C	Pathogenic	0.99
LRP5	O75197-1.2	I219D	Pathogenic	0.995
LRP5	O75197-1.2	I219E	Pathogenic	0.996
LRP5	O75197-1.2	I219F	Pathogenic	0.986
LRP5	O75197-1.2	I219G	Pathogenic	0.999
LRP5	O75197-1.2	I219H	Pathogenic	0.998
LRP5	O75197-1.2	I219K	Pathogenic	0.994
LRP5	O75197-1.2	I219L	Pathogenic	0.876
LRP5	O75197-1.2	I219M	Pathogenic	0.934
LRP5	O75197-1.2	I219N	Pathogenic	0.996
LRP5	O75197-1.2	I219P	Pathogenic	0.999
LRP5	O75197-1.2	I219Q	Pathogenic	0.997
LRP5	O75197-1.2	I219R	Pathogenic	0.994
LRP5	O75197-1.2	I219S	Pathogenic	0.992
LRP5	O75197-1.2	I219T	Pathogenic	0.981
LRP5	O75197-1.2	I219V	Pathogenic	0.594
LRP5	O75197-1.2	I219W	Pathogenic	0.999
LRP5	O75197-1.2	I219Y	Pathogenic	0.99
LRP5	O75197-1.2	H220A	Pathogenic	0.993
LRP5	O75197-1.2	H220C	Pathogenic	0.996
LRP5	O75197-1.2	H220D	Pathogenic	0.962
LRP5	O75197-1.2	H220E	Pathogenic	0.905
LRP5	O75197-1.2	H220F	Pathogenic	0.928
LRP5	O75197-1.2	H220G	Pathogenic	0.993
LRP5	O75197-1.2	H220I	Pathogenic	0.992
LRP5	O75197-1.2	H220K	Pathogenic	0.954
LRP5	O75197-1.2	H220L	Pathogenic	0.992
LRP5	O75197-1.2	H220M	Pathogenic	0.985
LRP5	O75197-1.2	H220N	Pathogenic	0.76
LRP5	O75197-1.2	H220P	Pathogenic	0.99
LRP5	O75197-1.2	H220Q	Pathogenic	0.933
LRP5	O75197-1.2	H220R	Pathogenic	0.869
LRP5	O75197-1.2	H220S	Pathogenic	0.979
LRP5	O75197-1.2	H220T	Pathogenic	0.994
LRP5	O75197-1.2	H220V	Pathogenic	0.995
LRP5	O75197-1.2	H220W	Pathogenic	0.961
LRP5	O75197-1.2	H220Y	Neutral	0.489
LRP5	O75197-1.2	R221A	Neutral	0.185
LRP5	O75197-1.2	R221C	Pathogenic	0.543
LRP5	O75197-1.2	R221D	Pathogenic	0.654
LRP5	O75197-1.2	R221E	Neutral	0.157
LRP5	O75197-1.2	R221F	Neutral	0.385
LRP5	O75197-1.2	R221G	Neutral	0.469
LRP5	O75197-1.2	R221H	Neutral	0.087
LRP5	O75197-1.2	R221I	Neutral	0.377
LRP5	O75197-1.2	R221K	Neutral	0.028
LRP5	O75197-1.2	R221L	Neutral	0.179
LRP5	O75197-1.2	R221M	Neutral	0.098
LRP5	O75197-1.2	R221N	Neutral	0.15
LRP5	O75197-1.2	R221P	Neutral	0.332
LRP5	O75197-1.2	R221Q	Neutral	0.041
LRP5	O75197-1.2	R221S	Neutral	0.238
LRP5	O75197-1.2	R221T	Neutral	0.199
LRP5	O75197-1.2	R221V	Neutral	0.498
LRP5	O75197-1.2	R221W	Neutral	0.292
LRP5	O75197-1.2	R221Y	Neutral	0.303
LRP5	O75197-1.2	A222C	Neutral	0.075
LRP5	O75197-1.2	A222D	Neutral	0.343
LRP5	O75197-1.2	A222E	Neutral	0.158
LRP5	O75197-1.2	A222F	Neutral	0.253
LRP5	O75197-1.2	A222G	Neutral	0.102
LRP5	O75197-1.2	A222H	Pathogenic	0.528
LRP5	O75197-1.2	A222I	Neutral	0.101
LRP5	O75197-1.2	A222K	Neutral	0.116
LRP5	O75197-1.2	A222L	Neutral	0.109
LRP5	O75197-1.2	A222M	Neutral	0.157
LRP5	O75197-1.2	A222N	Neutral	0.375
LRP5	O75197-1.2	A222P	Neutral	0.238
LRP5	O75197-1.2	A222Q	Neutral	0.213
LRP5	O75197-1.2	A222R	Neutral	0.113
LRP5	O75197-1.2	A222S	Neutral	0.035
LRP5	O75197-1.2	A222T	Neutral	0.123
LRP5	O75197-1.2	A222V	Neutral	0.06
LRP5	O75197-1.2	A222W	Neutral	0.395
LRP5	O75197-1.2	A222Y	Neutral	0.413
LRP5	O75197-1.2	N223A	Pathogenic	0.974
LRP5	O75197-1.2	N223C	Pathogenic	0.985
LRP5	O75197-1.2	N223D	Pathogenic	0.726
LRP5	O75197-1.2	N223E	Pathogenic	0.9
LRP5	O75197-1.2	N223F	Pathogenic	0.967
LRP5	O75197-1.2	N223G	Pathogenic	0.836
LRP5	O75197-1.2	N223H	Pathogenic	0.609
LRP5	O75197-1.2	N223I	Pathogenic	0.967
LRP5	O75197-1.2	N223K	Pathogenic	0.862
LRP5	O75197-1.2	N223L	Pathogenic	0.97
LRP5	O75197-1.2	N223M	Pathogenic	0.942
LRP5	O75197-1.2	N223P	Pathogenic	0.964
LRP5	O75197-1.2	N223Q	Pathogenic	0.867
LRP5	O75197-1.2	N223R	Pathogenic	0.858
LRP5	O75197-1.2	N223S	Pathogenic	0.644
LRP5	O75197-1.2	N223T	Pathogenic	0.814
LRP5	O75197-1.2	N223V	Pathogenic	0.981
LRP5	O75197-1.2	N223W	Pathogenic	0.983
LRP5	O75197-1.2	N223Y	Pathogenic	0.953
LRP5	O75197-1.2	L224A	Pathogenic	0.71
LRP5	O75197-1.2	L224C	Pathogenic	0.822
LRP5	O75197-1.2	L224D	Pathogenic	0.965
LRP5	O75197-1.2	L224E	Pathogenic	0.912
LRP5	O75197-1.2	L224F	Pathogenic	0.736
LRP5	O75197-1.2	L224G	Pathogenic	0.981
LRP5	O75197-1.2	L224H	Pathogenic	0.955
LRP5	O75197-1.2	L224I	Neutral	0.232
LRP5	O75197-1.2	L224K	Pathogenic	0.715
LRP5	O75197-1.2	L224M	Neutral	0.179
LRP5	O75197-1.2	L224N	Pathogenic	0.913
LRP5	O75197-1.2	L224P	Pathogenic	0.971
LRP5	O75197-1.2	L224Q	Pathogenic	0.834
LRP5	O75197-1.2	L224R	Pathogenic	0.708
LRP5	O75197-1.2	L224S	Pathogenic	0.847
LRP5	O75197-1.2	L224T	Pathogenic	0.709
LRP5	O75197-1.2	L224V	Neutral	0.388
LRP5	O75197-1.2	L224W	Pathogenic	0.942
LRP5	O75197-1.2	L224Y	Pathogenic	0.824
LRP5	O75197-1.2	D225A	Pathogenic	0.908
LRP5	O75197-1.2	D225C	Pathogenic	0.944
LRP5	O75197-1.2	D225E	Neutral	0.213
LRP5	O75197-1.2	D225F	Pathogenic	0.886
LRP5	O75197-1.2	D225G	Pathogenic	0.806
LRP5	O75197-1.2	D225H	Pathogenic	0.791
LRP5	O75197-1.2	D225I	Pathogenic	0.886
LRP5	O75197-1.2	D225K	Pathogenic	0.871
LRP5	O75197-1.2	D225L	Pathogenic	0.963
LRP5	O75197-1.2	D225M	Pathogenic	0.928
LRP5	O75197-1.2	D225N	Neutral	0.449
LRP5	O75197-1.2	D225P	Pathogenic	0.7
LRP5	O75197-1.2	D225Q	Pathogenic	0.632
LRP5	O75197-1.2	D225R	Pathogenic	0.952
LRP5	O75197-1.2	D225S	Pathogenic	0.595
LRP5	O75197-1.2	D225T	Pathogenic	0.779
LRP5	O75197-1.2	D225V	Pathogenic	0.931
LRP5	O75197-1.2	D225W	Pathogenic	0.937
LRP5	O75197-1.2	D225Y	Pathogenic	0.941
LRP5	O75197-1.2	G226A	Pathogenic	0.979
LRP5	O75197-1.2	G226C	Pathogenic	0.999
LRP5	O75197-1.2	G226D	Pathogenic	0.989
LRP5	O75197-1.2	G226E	Pathogenic	0.997
LRP5	O75197-1.2	G226F	Pathogenic	0.997
LRP5	O75197-1.2	G226H	Pathogenic	0.998
LRP5	O75197-1.2	G226I	Pathogenic	0.999
LRP5	O75197-1.2	G226K	Pathogenic	0.995
LRP5	O75197-1.2	G226L	Pathogenic	0.999
LRP5	O75197-1.2	G226M	Pathogenic	0.998
LRP5	O75197-1.2	G226N	Pathogenic	0.972
LRP5	O75197-1.2	G226P	Pathogenic	0.997
LRP5	O75197-1.2	G226Q	Pathogenic	0.998
LRP5	O75197-1.2	G226R	Pathogenic	0.995
LRP5	O75197-1.2	G226S	Pathogenic	0.983
LRP5	O75197-1.2	G226T	Pathogenic	0.998
LRP5	O75197-1.2	G226V	Pathogenic	0.998
LRP5	O75197-1.2	G226W	Pathogenic	0.985
LRP5	O75197-1.2	G226Y	Pathogenic	0.998
LRP5	O75197-1.2	S227A	Neutral	0.067
LRP5	O75197-1.2	S227C	Neutral	0.266
LRP5	O75197-1.2	S227D	Neutral	0.132
LRP5	O75197-1.2	S227E	Neutral	0.143
LRP5	O75197-1.2	S227F	Neutral	0.331
LRP5	O75197-1.2	S227G	Neutral	0.219
LRP5	O75197-1.2	S227H	Neutral	0.424
LRP5	O75197-1.2	S227I	Neutral	0.332
LRP5	O75197-1.2	S227K	Neutral	0.105
LRP5	O75197-1.2	S227L	Neutral	0.353
LRP5	O75197-1.2	S227M	Neutral	0.214
LRP5	O75197-1.2	S227N	Neutral	0.055
LRP5	O75197-1.2	S227P	Neutral	0.313
LRP5	O75197-1.2	S227Q	Neutral	0.194
LRP5	O75197-1.2	S227R	Neutral	0.256
LRP5	O75197-1.2	S227T	Neutral	0.069
LRP5	O75197-1.2	S227V	Neutral	0.464
LRP5	O75197-1.2	S227W	Neutral	0.488
LRP5	O75197-1.2	S227Y	Pathogenic	0.507
LRP5	O75197-1.2	F228A	Neutral	0.121
LRP5	O75197-1.2	F228C	Neutral	0.205
LRP5	O75197-1.2	F228D	Neutral	0.142
LRP5	O75197-1.2	F228E	Neutral	0.161
LRP5	O75197-1.2	F228G	Neutral	0.235
LRP5	O75197-1.2	F228H	Neutral	0.04
LRP5	O75197-1.2	F228I	Neutral	0.057
LRP5	O75197-1.2	F228K	Neutral	0.127
LRP5	O75197-1.2	F228L	Neutral	0.053
LRP5	O75197-1.2	F228M	Neutral	0.036
LRP5	O75197-1.2	F228N	Neutral	0.162
LRP5	O75197-1.2	F228P	Pathogenic	0.655
LRP5	O75197-1.2	F228Q	Neutral	0.219
LRP5	O75197-1.2	F228R	Neutral	0.124
LRP5	O75197-1.2	F228S	Neutral	0.092
LRP5	O75197-1.2	F228T	Neutral	0.12
LRP5	O75197-1.2	F228V	Neutral	0.098
LRP5	O75197-1.2	F228W	Neutral	0.013
LRP5	O75197-1.2	F228Y	Neutral	0.001
LRP5	O75197-1.2	R229A	Pathogenic	0.967
LRP5	O75197-1.2	R229C	Pathogenic	0.993
LRP5	O75197-1.2	R229D	Pathogenic	0.996
LRP5	O75197-1.2	R229E	Pathogenic	0.96
LRP5	O75197-1.2	R229F	Pathogenic	0.988
LRP5	O75197-1.2	R229G	Pathogenic	0.991
LRP5	O75197-1.2	R229H	Pathogenic	0.924
LRP5	O75197-1.2	R229I	Pathogenic	0.987
LRP5	O75197-1.2	R229K	Pathogenic	0.786
LRP5	O75197-1.2	R229L	Pathogenic	0.965
LRP5	O75197-1.2	R229M	Pathogenic	0.933
LRP5	O75197-1.2	R229N	Pathogenic	0.957
LRP5	O75197-1.2	R229P	Pathogenic	0.984
LRP5	O75197-1.2	R229Q	Pathogenic	0.844
LRP5	O75197-1.2	R229S	Pathogenic	0.976
LRP5	O75197-1.2	R229T	Pathogenic	0.969
LRP5	O75197-1.2	R229V	Pathogenic	0.992
LRP5	O75197-1.2	R229W	Pathogenic	0.981
LRP5	O75197-1.2	R229Y	Pathogenic	0.982
LRP5	O75197-1.2	Q230A	Pathogenic	0.75
LRP5	O75197-1.2	Q230C	Pathogenic	0.94
LRP5	O75197-1.2	Q230D	Pathogenic	0.501
LRP5	O75197-1.2	Q230E	Neutral	0.112
LRP5	O75197-1.2	Q230F	Pathogenic	0.885
LRP5	O75197-1.2	Q230G	Pathogenic	0.921
LRP5	O75197-1.2	Q230H	Pathogenic	0.553
LRP5	O75197-1.2	Q230I	Pathogenic	0.885
LRP5	O75197-1.2	Q230K	Neutral	0.214
LRP5	O75197-1.2	Q230L	Pathogenic	0.736
LRP5	O75197-1.2	Q230M	Neutral	0.314
LRP5	O75197-1.2	Q230N	Pathogenic	0.541
LRP5	O75197-1.2	Q230P	Pathogenic	0.683
LRP5	O75197-1.2	Q230R	Neutral	0.208
LRP5	O75197-1.2	Q230S	Pathogenic	0.575
LRP5	O75197-1.2	Q230T	Pathogenic	0.766
LRP5	O75197-1.2	Q230V	Pathogenic	0.811
LRP5	O75197-1.2	Q230W	Pathogenic	0.615
LRP5	O75197-1.2	Q230Y	Pathogenic	0.633
LRP5	O75197-1.2	K231A	Neutral	0.107
LRP5	O75197-1.2	K231C	Neutral	0.386
LRP5	O75197-1.2	K231D	Neutral	0.247
LRP5	O75197-1.2	K231E	Neutral	0.031
LRP5	O75197-1.2	K231F	Neutral	0.248
LRP5	O75197-1.2	K231G	Neutral	0.318
LRP5	O75197-1.2	K231H	Neutral	0.133
LRP5	O75197-1.2	K231I	Neutral	0.243
LRP5	O75197-1.2	K231L	Neutral	0.103
LRP5	O75197-1.2	K231M	Neutral	0.055
LRP5	O75197-1.2	K231N	Neutral	0.085
LRP5	O75197-1.2	K231P	Neutral	0.08
LRP5	O75197-1.2	K231Q	Neutral	0.022
LRP5	O75197-1.2	K231R	Neutral	0.014
LRP5	O75197-1.2	K231S	Neutral	0.052
LRP5	O75197-1.2	K231T	Neutral	0.116
LRP5	O75197-1.2	K231V	Neutral	0.147
LRP5	O75197-1.2	K231W	Neutral	0.173
LRP5	O75197-1.2	K231Y	Neutral	0.184
LRP5	O75197-1.2	V232A	Pathogenic	0.888
LRP5	O75197-1.2	V232C	Pathogenic	0.978
LRP5	O75197-1.2	V232D	Pathogenic	0.989
LRP5	O75197-1.2	V232E	Pathogenic	0.971
LRP5	O75197-1.2	V232F	Pathogenic	0.971
LRP5	O75197-1.2	V232G	Pathogenic	0.994
LRP5	O75197-1.2	V232H	Pathogenic	0.995
LRP5	O75197-1.2	V232I	Neutral	0.278
LRP5	O75197-1.2	V232K	Pathogenic	0.959
LRP5	O75197-1.2	V232L	Pathogenic	0.797
LRP5	O75197-1.2	V232M	Pathogenic	0.856
LRP5	O75197-1.2	V232N	Pathogenic	0.99
LRP5	O75197-1.2	V232P	Pathogenic	0.991
LRP5	O75197-1.2	V232Q	Pathogenic	0.979
LRP5	O75197-1.2	V232R	Pathogenic	0.986
LRP5	O75197-1.2	V232S	Pathogenic	0.982
LRP5	O75197-1.2	V232T	Pathogenic	0.887
LRP5	O75197-1.2	V232W	Pathogenic	0.995
LRP5	O75197-1.2	V232Y	Pathogenic	0.977
LRP5	O75197-1.2	V233A	Pathogenic	0.722
LRP5	O75197-1.2	V233C	Pathogenic	0.937
LRP5	O75197-1.2	V233D	Pathogenic	0.967
LRP5	O75197-1.2	V233E	Pathogenic	0.916
LRP5	O75197-1.2	V233F	Pathogenic	0.915
LRP5	O75197-1.2	V233G	Pathogenic	0.982
LRP5	O75197-1.2	V233H	Pathogenic	0.985
LRP5	O75197-1.2	V233I	Neutral	0.112
LRP5	O75197-1.2	V233K	Pathogenic	0.884
LRP5	O75197-1.2	V233L	Pathogenic	0.562
LRP5	O75197-1.2	V233M	Pathogenic	0.662
LRP5	O75197-1.2	V233N	Pathogenic	0.971
LRP5	O75197-1.2	V233P	Pathogenic	0.973
LRP5	O75197-1.2	V233Q	Pathogenic	0.94
LRP5	O75197-1.2	V233R	Pathogenic	0.957
LRP5	O75197-1.2	V233S	Pathogenic	0.947
LRP5	O75197-1.2	V233T	Pathogenic	0.721
LRP5	O75197-1.2	V233W	Pathogenic	0.984
LRP5	O75197-1.2	V233Y	Pathogenic	0.934
LRP5	O75197-1.2	E234A	Neutral	0.261
LRP5	O75197-1.2	E234C	Pathogenic	0.849
LRP5	O75197-1.2	E234D	Neutral	0.026
LRP5	O75197-1.2	E234F	Neutral	0.472
LRP5	O75197-1.2	E234G	Pathogenic	0.579
LRP5	O75197-1.2	E234H	Neutral	0.125
LRP5	O75197-1.2	E234I	Neutral	0.473
LRP5	O75197-1.2	E234K	Neutral	0.063
LRP5	O75197-1.2	E234L	Neutral	0.496
LRP5	O75197-1.2	E234M	Neutral	0.33
LRP5	O75197-1.2	E234N	Neutral	0.215
LRP5	O75197-1.2	E234P	Neutral	0.203
LRP5	O75197-1.2	E234Q	Neutral	0.021
LRP5	O75197-1.2	E234R	Neutral	0.164
LRP5	O75197-1.2	E234S	Neutral	0.138
LRP5	O75197-1.2	E234T	Neutral	0.279
LRP5	O75197-1.2	E234V	Neutral	0.337
LRP5	O75197-1.2	E234W	Neutral	0.361
LRP5	O75197-1.2	E234Y	Neutral	0.379
LRP5	O75197-1.2	G235A	Pathogenic	0.799
LRP5	O75197-1.2	G235C	Pathogenic	0.983
LRP5	O75197-1.2	G235D	Pathogenic	0.885
LRP5	O75197-1.2	G235E	Pathogenic	0.962
LRP5	O75197-1.2	G235F	Pathogenic	0.964
LRP5	O75197-1.2	G235H	Pathogenic	0.975
LRP5	O75197-1.2	G235I	Pathogenic	0.988
LRP5	O75197-1.2	G235K	Pathogenic	0.947
LRP5	O75197-1.2	G235L	Pathogenic	0.989
LRP5	O75197-1.2	G235M	Pathogenic	0.978
LRP5	O75197-1.2	G235N	Pathogenic	0.745
LRP5	O75197-1.2	G235P	Pathogenic	0.961
LRP5	O75197-1.2	G235Q	Pathogenic	0.974
LRP5	O75197-1.2	G235R	Pathogenic	0.945
LRP5	O75197-1.2	G235S	Pathogenic	0.834
LRP5	O75197-1.2	G235T	Pathogenic	0.974
LRP5	O75197-1.2	G235V	Pathogenic	0.979
LRP5	O75197-1.2	G235W	Pathogenic	0.847
LRP5	O75197-1.2	G235Y	Pathogenic	0.982
LRP5	O75197-1.2	S236A	Neutral	0.077
LRP5	O75197-1.2	S236C	Neutral	0.294
LRP5	O75197-1.2	S236D	Neutral	0.149
LRP5	O75197-1.2	S236E	Neutral	0.161
LRP5	O75197-1.2	S236F	Neutral	0.363
LRP5	O75197-1.2	S236G	Neutral	0.245
LRP5	O75197-1.2	S236H	Neutral	0.459
LRP5	O75197-1.2	S236I	Neutral	0.364
LRP5	O75197-1.2	S236K	Neutral	0.119
LRP5	O75197-1.2	S236L	Neutral	0.386
LRP5	O75197-1.2	S236M	Neutral	0.239
LRP5	O75197-1.2	S236N	Neutral	0.062
LRP5	O75197-1.2	S236P	Neutral	0.344
LRP5	O75197-1.2	S236Q	Neutral	0.217
LRP5	O75197-1.2	S236R	Neutral	0.283
LRP5	O75197-1.2	S236T	Neutral	0.079
LRP5	O75197-1.2	S236V	Neutral	0.5
LRP5	O75197-1.2	S236W	Pathogenic	0.523
LRP5	O75197-1.2	S236Y	Pathogenic	0.542
LRP5	O75197-1.2	L237A	Pathogenic	0.968
LRP5	O75197-1.2	L237C	Pathogenic	0.983
LRP5	O75197-1.2	L237D	Pathogenic	0.997
LRP5	O75197-1.2	L237E	Pathogenic	0.992
LRP5	O75197-1.2	L237F	Pathogenic	0.971
LRP5	O75197-1.2	L237G	Pathogenic	0.998
LRP5	O75197-1.2	L237H	Pathogenic	0.996
LRP5	O75197-1.2	L237I	Pathogenic	0.787
LRP5	O75197-1.2	L237K	Pathogenic	0.969
LRP5	O75197-1.2	L237M	Pathogenic	0.727
LRP5	O75197-1.2	L237N	Pathogenic	0.992
LRP5	O75197-1.2	L237P	Pathogenic	0.998
LRP5	O75197-1.2	L237Q	Pathogenic	0.984
LRP5	O75197-1.2	L237R	Pathogenic	0.967
LRP5	O75197-1.2	L237S	Pathogenic	0.985
LRP5	O75197-1.2	L237T	Pathogenic	0.968
LRP5	O75197-1.2	L237V	Pathogenic	0.886
LRP5	O75197-1.2	L237W	Pathogenic	0.995
LRP5	O75197-1.2	L237Y	Pathogenic	0.983
LRP5	O75197-1.2	T238A	Neutral	0.159
LRP5	O75197-1.2	T238C	Neutral	0.245
LRP5	O75197-1.2	T238D	Neutral	0.2
LRP5	O75197-1.2	T238E	Neutral	0.215
LRP5	O75197-1.2	T238F	Neutral	0.312
LRP5	O75197-1.2	T238G	Pathogenic	0.585
LRP5	O75197-1.2	T238H	Pathogenic	0.621
LRP5	O75197-1.2	T238I	Neutral	0.13
LRP5	O75197-1.2	T238K	Neutral	0.161
LRP5	O75197-1.2	T238L	Neutral	0.141
LRP5	O75197-1.2	T238M	Neutral	0.2
LRP5	O75197-1.2	T238N	Neutral	0.087
LRP5	O75197-1.2	T238P	Neutral	0.292
LRP5	O75197-1.2	T238Q	Neutral	0.284
LRP5	O75197-1.2	T238R	Neutral	0.157
LRP5	O75197-1.2	T238S	Neutral	0.048
LRP5	O75197-1.2	T238V	Neutral	0.079
LRP5	O75197-1.2	T238W	Neutral	0.223
LRP5	O75197-1.2	T238Y	Neutral	0.485
LRP5	O75197-1.2	H239A	Pathogenic	0.997
LRP5	O75197-1.2	H239C	Pathogenic	0.998
LRP5	O75197-1.2	H239D	Pathogenic	0.985
LRP5	O75197-1.2	H239E	Pathogenic	0.961
LRP5	O75197-1.2	H239F	Pathogenic	0.971
LRP5	O75197-1.2	H239G	Pathogenic	0.997
LRP5	O75197-1.2	H239I	Pathogenic	0.997
LRP5	O75197-1.2	H239K	Pathogenic	0.982
LRP5	O75197-1.2	H239L	Pathogenic	0.997
LRP5	O75197-1.2	H239M	Pathogenic	0.994
LRP5	O75197-1.2	H239N	Pathogenic	0.892
LRP5	O75197-1.2	H239P	Pathogenic	0.996
LRP5	O75197-1.2	H239Q	Pathogenic	0.973
LRP5	O75197-1.2	H239R	Pathogenic	0.945
LRP5	O75197-1.2	H239S	Pathogenic	0.992
LRP5	O75197-1.2	H239T	Pathogenic	0.997
LRP5	O75197-1.2	H239V	Pathogenic	0.998
LRP5	O75197-1.2	H239W	Pathogenic	0.985
LRP5	O75197-1.2	H239Y	Pathogenic	0.713
LRP5	O75197-1.2	P240A	Pathogenic	0.994
LRP5	O75197-1.2	P240C	Pathogenic	0.999
LRP5	O75197-1.2	P240D	Pathogenic	0.985
LRP5	O75197-1.2	P240E	Pathogenic	0.986
LRP5	O75197-1.2	P240F	Pathogenic	1.0
LRP5	O75197-1.2	P240G	Pathogenic	0.997
LRP5	O75197-1.2	P240H	Pathogenic	0.998
LRP5	O75197-1.2	P240I	Pathogenic	0.999
LRP5	O75197-1.2	P240K	Pathogenic	0.98
LRP5	O75197-1.2	P240L	Pathogenic	0.999
LRP5	O75197-1.2	P240M	Pathogenic	0.998
LRP5	O75197-1.2	P240N	Pathogenic	0.996
LRP5	O75197-1.2	P240Q	Pathogenic	0.99
LRP5	O75197-1.2	P240R	Pathogenic	0.993
LRP5	O75197-1.2	P240S	Pathogenic	0.992
LRP5	O75197-1.2	P240T	Pathogenic	0.994
LRP5	O75197-1.2	P240V	Pathogenic	0.998
LRP5	O75197-1.2	P240W	Pathogenic	0.999
LRP5	O75197-1.2	P240Y	Pathogenic	0.999
LRP5	O75197-1.2	F241A	Pathogenic	0.997
LRP5	O75197-1.2	F241C	Pathogenic	0.999
LRP5	O75197-1.2	F241D	Pathogenic	0.998
LRP5	O75197-1.2	F241E	Pathogenic	0.998
LRP5	O75197-1.2	F241G	Pathogenic	0.999
LRP5	O75197-1.2	F241H	Pathogenic	0.992
LRP5	O75197-1.2	F241I	Pathogenic	0.994
LRP5	O75197-1.2	F241K	Pathogenic	0.998
LRP5	O75197-1.2	F241L	Pathogenic	0.994
LRP5	O75197-1.2	F241M	Pathogenic	0.991
LRP5	O75197-1.2	F241N	Pathogenic	0.998
LRP5	O75197-1.2	F241P	Pathogenic	1.0
LRP5	O75197-1.2	F241Q	Pathogenic	0.999
LRP5	O75197-1.2	F241R	Pathogenic	0.997
LRP5	O75197-1.2	F241S	Pathogenic	0.997
LRP5	O75197-1.2	F241T	Pathogenic	0.997
LRP5	O75197-1.2	F241V	Pathogenic	0.997
LRP5	O75197-1.2	F241W	Pathogenic	0.973
LRP5	O75197-1.2	F241Y	Pathogenic	0.746
LRP5	O75197-1.2	A242C	Pathogenic	0.971
LRP5	O75197-1.2	A242D	Pathogenic	0.995
LRP5	O75197-1.2	A242E	Pathogenic	0.987
LRP5	O75197-1.2	A242F	Pathogenic	0.993
LRP5	O75197-1.2	A242G	Pathogenic	0.979
LRP5	O75197-1.2	A242H	Pathogenic	0.998
LRP5	O75197-1.2	A242I	Pathogenic	0.979
LRP5	O75197-1.2	A242K	Pathogenic	0.982
LRP5	O75197-1.2	A242L	Pathogenic	0.98
LRP5	O75197-1.2	A242M	Pathogenic	0.987
LRP5	O75197-1.2	A242N	Pathogenic	0.996
LRP5	O75197-1.2	A242P	Pathogenic	0.992
LRP5	O75197-1.2	A242Q	Pathogenic	0.991
LRP5	O75197-1.2	A242R	Pathogenic	0.981
LRP5	O75197-1.2	A242S	Pathogenic	0.937
LRP5	O75197-1.2	A242T	Pathogenic	0.983
LRP5	O75197-1.2	A242V	Pathogenic	0.963
LRP5	O75197-1.2	A242W	Pathogenic	0.996
LRP5	O75197-1.2	A242Y	Pathogenic	0.997
LRP5	O75197-1.2	L243A	Pathogenic	0.882
LRP5	O75197-1.2	L243C	Pathogenic	0.934
LRP5	O75197-1.2	L243D	Pathogenic	0.988
LRP5	O75197-1.2	L243E	Pathogenic	0.969
LRP5	O75197-1.2	L243F	Pathogenic	0.895
LRP5	O75197-1.2	L243G	Pathogenic	0.994
LRP5	O75197-1.2	L243H	Pathogenic	0.985
LRP5	O75197-1.2	L243I	Neutral	0.479
LRP5	O75197-1.2	L243K	Pathogenic	0.885
LRP5	O75197-1.2	L243M	Neutral	0.399
LRP5	O75197-1.2	L243N	Pathogenic	0.97
LRP5	O75197-1.2	L243P	Pathogenic	0.99
LRP5	O75197-1.2	L243Q	Pathogenic	0.939
LRP5	O75197-1.2	L243R	Pathogenic	0.881
LRP5	O75197-1.2	L243S	Pathogenic	0.944
LRP5	O75197-1.2	L243T	Pathogenic	0.881
LRP5	O75197-1.2	L243V	Pathogenic	0.659
LRP5	O75197-1.2	L243W	Pathogenic	0.98
LRP5	O75197-1.2	L243Y	Pathogenic	0.934
LRP5	O75197-1.2	T244A	Pathogenic	0.973
LRP5	O75197-1.2	T244C	Pathogenic	0.984
LRP5	O75197-1.2	T244D	Pathogenic	0.98
LRP5	O75197-1.2	T244E	Pathogenic	0.982
LRP5	O75197-1.2	T244F	Pathogenic	0.989
LRP5	O75197-1.2	T244G	Pathogenic	0.996
LRP5	O75197-1.2	T244H	Pathogenic	0.997
LRP5	O75197-1.2	T244I	Pathogenic	0.967
LRP5	O75197-1.2	T244K	Pathogenic	0.974
LRP5	O75197-1.2	T244L	Pathogenic	0.969
LRP5	O75197-1.2	T244M	Pathogenic	0.98
LRP5	O75197-1.2	T244N	Pathogenic	0.949
LRP5	O75197-1.2	T244P	Pathogenic	0.988
LRP5	O75197-1.2	T244Q	Pathogenic	0.987
LRP5	O75197-1.2	T244R	Pathogenic	0.973
LRP5	O75197-1.2	T244S	Pathogenic	0.907
LRP5	O75197-1.2	T244V	Pathogenic	0.943
LRP5	O75197-1.2	T244W	Pathogenic	0.982
LRP5	O75197-1.2	T244Y	Pathogenic	0.995
LRP5	O75197-1.2	L245A	Pathogenic	0.726
LRP5	O75197-1.2	L245C	Pathogenic	0.833
LRP5	O75197-1.2	L245D	Pathogenic	0.967
LRP5	O75197-1.2	L245E	Pathogenic	0.918
LRP5	O75197-1.2	L245F	Pathogenic	0.75
LRP5	O75197-1.2	L245G	Pathogenic	0.982
LRP5	O75197-1.2	L245H	Pathogenic	0.958
LRP5	O75197-1.2	L245I	Neutral	0.246
LRP5	O75197-1.2	L245K	Pathogenic	0.731
LRP5	O75197-1.2	L245M	Neutral	0.19
LRP5	O75197-1.2	L245N	Pathogenic	0.919
LRP5	O75197-1.2	L245P	Pathogenic	0.973
LRP5	O75197-1.2	L245Q	Pathogenic	0.844
LRP5	O75197-1.2	L245R	Pathogenic	0.724
LRP5	O75197-1.2	L245S	Pathogenic	0.856
LRP5	O75197-1.2	L245T	Pathogenic	0.725
LRP5	O75197-1.2	L245V	Neutral	0.406
LRP5	O75197-1.2	L245W	Pathogenic	0.946
LRP5	O75197-1.2	L245Y	Pathogenic	0.835
LRP5	O75197-1.2	S246A	Neutral	0.024
LRP5	O75197-1.2	S246C	Neutral	0.108
LRP5	O75197-1.2	S246D	Neutral	0.048
LRP5	O75197-1.2	S246E	Neutral	0.053
LRP5	O75197-1.2	S246F	Neutral	0.142
LRP5	O75197-1.2	S246G	Neutral	0.086
LRP5	O75197-1.2	S246H	Neutral	0.197
LRP5	O75197-1.2	S246I	Neutral	0.142
LRP5	O75197-1.2	S246K	Neutral	0.038
LRP5	O75197-1.2	S246L	Neutral	0.154
LRP5	O75197-1.2	S246M	Neutral	0.083
LRP5	O75197-1.2	S246N	Neutral	0.019
LRP5	O75197-1.2	S246P	Neutral	0.132
LRP5	O75197-1.2	S246Q	Neutral	0.074
LRP5	O75197-1.2	S246R	Neutral	0.103
LRP5	O75197-1.2	S246T	Neutral	0.024
LRP5	O75197-1.2	S246V	Neutral	0.224
LRP5	O75197-1.2	S246W	Neutral	0.241
LRP5	O75197-1.2	S246Y	Neutral	0.256
LRP5	O75197-1.2	G247A	Neutral	0.125
LRP5	O75197-1.2	G247C	Pathogenic	0.681
LRP5	O75197-1.2	G247D	Neutral	0.216
LRP5	O75197-1.2	G247E	Neutral	0.479
LRP5	O75197-1.2	G247F	Neutral	0.489
LRP5	O75197-1.2	G247H	Pathogenic	0.587
LRP5	O75197-1.2	G247I	Pathogenic	0.745
LRP5	O75197-1.2	G247K	Neutral	0.391
LRP5	O75197-1.2	G247L	Pathogenic	0.762
LRP5	O75197-1.2	G247M	Pathogenic	0.616
LRP5	O75197-1.2	G247N	Neutral	0.095
LRP5	O75197-1.2	G247P	Neutral	0.468
LRP5	O75197-1.2	G247Q	Pathogenic	0.57
LRP5	O75197-1.2	G247R	Neutral	0.383
LRP5	O75197-1.2	G247S	Neutral	0.153
LRP5	O75197-1.2	G247T	Pathogenic	0.57
LRP5	O75197-1.2	G247V	Pathogenic	0.626
LRP5	O75197-1.2	G247W	Neutral	0.166
LRP5	O75197-1.2	G247Y	Pathogenic	0.665
LRP5	O75197-1.2	D248A	Pathogenic	0.755
LRP5	O75197-1.2	D248C	Pathogenic	0.841
LRP5	O75197-1.2	D248E	Neutral	0.078
LRP5	O75197-1.2	D248F	Pathogenic	0.707
LRP5	O75197-1.2	D248G	Pathogenic	0.564
LRP5	O75197-1.2	D248H	Pathogenic	0.541
LRP5	O75197-1.2	D248I	Pathogenic	0.708
LRP5	O75197-1.2	D248K	Pathogenic	0.679
LRP5	O75197-1.2	D248L	Pathogenic	0.89
LRP5	O75197-1.2	D248M	Pathogenic	0.802
LRP5	O75197-1.2	D248N	Neutral	0.203
LRP5	O75197-1.2	D248P	Neutral	0.421
LRP5	O75197-1.2	D248Q	Neutral	0.348
LRP5	O75197-1.2	D248R	Pathogenic	0.861
LRP5	O75197-1.2	D248S	Neutral	0.314
LRP5	O75197-1.2	D248T	Pathogenic	0.524
LRP5	O75197-1.2	D248V	Pathogenic	0.809
LRP5	O75197-1.2	D248W	Pathogenic	0.823
LRP5	O75197-1.2	D248Y	Pathogenic	0.834
LRP5	O75197-1.2	T249A	Pathogenic	0.629
LRP5	O75197-1.2	T249C	Pathogenic	0.745
LRP5	O75197-1.2	T249D	Pathogenic	0.692
LRP5	O75197-1.2	T249E	Pathogenic	0.712
LRP5	O75197-1.2	T249F	Pathogenic	0.803
LRP5	O75197-1.2	T249G	Pathogenic	0.927
LRP5	O75197-1.2	T249H	Pathogenic	0.936
LRP5	O75197-1.2	T249I	Pathogenic	0.574
LRP5	O75197-1.2	T249K	Pathogenic	0.634
LRP5	O75197-1.2	T249L	Pathogenic	0.596
LRP5	O75197-1.2	T249M	Pathogenic	0.692
LRP5	O75197-1.2	T249N	Neutral	0.461
LRP5	O75197-1.2	T249P	Pathogenic	0.788
LRP5	O75197-1.2	T249Q	Pathogenic	0.781
LRP5	O75197-1.2	T249R	Pathogenic	0.626
LRP5	O75197-1.2	T249S	Neutral	0.312
LRP5	O75197-1.2	T249V	Neutral	0.435
LRP5	O75197-1.2	T249W	Pathogenic	0.721
LRP5	O75197-1.2	T249Y	Pathogenic	0.894
LRP5	O75197-1.2	L250A	Pathogenic	0.959
LRP5	O75197-1.2	L250C	Pathogenic	0.978
LRP5	O75197-1.2	L250D	Pathogenic	0.996
LRP5	O75197-1.2	L250E	Pathogenic	0.99
LRP5	O75197-1.2	L250F	Pathogenic	0.964
LRP5	O75197-1.2	L250G	Pathogenic	0.998
LRP5	O75197-1.2	L250H	Pathogenic	0.995
LRP5	O75197-1.2	L250I	Pathogenic	0.744
LRP5	O75197-1.2	L250K	Pathogenic	0.96
LRP5	O75197-1.2	L250M	Pathogenic	0.677
LRP5	O75197-1.2	L250N	Pathogenic	0.99
LRP5	O75197-1.2	L250P	Pathogenic	0.997
LRP5	O75197-1.2	L250Q	Pathogenic	0.98
LRP5	O75197-1.2	L250R	Pathogenic	0.959
LRP5	O75197-1.2	L250S	Pathogenic	0.982
LRP5	O75197-1.2	L250T	Pathogenic	0.959
LRP5	O75197-1.2	L250V	Pathogenic	0.859
LRP5	O75197-1.2	L250W	Pathogenic	0.994
LRP5	O75197-1.2	L250Y	Pathogenic	0.978
LRP5	O75197-1.2	Y251A	Pathogenic	0.992
LRP5	O75197-1.2	Y251C	Pathogenic	0.996
LRP5	O75197-1.2	Y251D	Pathogenic	0.993
LRP5	O75197-1.2	Y251E	Pathogenic	0.983
LRP5	O75197-1.2	Y251F	Neutral	0.312
LRP5	O75197-1.2	Y251G	Pathogenic	0.996
LRP5	O75197-1.2	Y251H	Pathogenic	0.573
LRP5	O75197-1.2	Y251I	Pathogenic	0.974
LRP5	O75197-1.2	Y251K	Pathogenic	0.977
LRP5	O75197-1.2	Y251L	Pathogenic	0.976
LRP5	O75197-1.2	Y251M	Pathogenic	0.984
LRP5	O75197-1.2	Y251N	Pathogenic	0.983
LRP5	O75197-1.2	Y251P	Pathogenic	0.998
LRP5	O75197-1.2	Y251Q	Pathogenic	0.965
LRP5	O75197-1.2	Y251R	Pathogenic	0.977
LRP5	O75197-1.2	Y251S	Pathogenic	0.989
LRP5	O75197-1.2	Y251T	Pathogenic	0.992
LRP5	O75197-1.2	Y251V	Pathogenic	0.984
LRP5	O75197-1.2	Y251W	Neutral	0.471
LRP5	O75197-1.2	W252A	Pathogenic	0.999
LRP5	O75197-1.2	W252C	Pathogenic	0.999
LRP5	O75197-1.2	W252D	Pathogenic	0.999
LRP5	O75197-1.2	W252E	Pathogenic	0.998
LRP5	O75197-1.2	W252F	Pathogenic	0.982
LRP5	O75197-1.2	W252G	Pathogenic	0.996
LRP5	O75197-1.2	W252H	Pathogenic	0.997
LRP5	O75197-1.2	W252I	Pathogenic	1.0
LRP5	O75197-1.2	W252K	Pathogenic	0.997
LRP5	O75197-1.2	W252L	Pathogenic	0.999
LRP5	O75197-1.2	W252M	Pathogenic	0.997
LRP5	O75197-1.2	W252N	Pathogenic	0.999
LRP5	O75197-1.2	W252P	Pathogenic	1.0
LRP5	O75197-1.2	W252Q	Pathogenic	0.996
LRP5	O75197-1.2	W252R	Pathogenic	0.997
LRP5	O75197-1.2	W252S	Pathogenic	0.999
LRP5	O75197-1.2	W252T	Pathogenic	0.997
LRP5	O75197-1.2	W252V	Pathogenic	1.0
LRP5	O75197-1.2	W252Y	Pathogenic	0.894
LRP5	O75197-1.2	T253A	Pathogenic	0.981
LRP5	O75197-1.2	T253C	Pathogenic	0.989
LRP5	O75197-1.2	T253D	Pathogenic	0.985
LRP5	O75197-1.2	T253E	Pathogenic	0.987
LRP5	O75197-1.2	T253F	Pathogenic	0.992
LRP5	O75197-1.2	T253G	Pathogenic	0.997
LRP5	O75197-1.2	T253H	Pathogenic	0.998
LRP5	O75197-1.2	T253I	Pathogenic	0.976
LRP5	O75197-1.2	T253K	Pathogenic	0.981
LRP5	O75197-1.2	T253L	Pathogenic	0.978
LRP5	O75197-1.2	T253M	Pathogenic	0.985
LRP5	O75197-1.2	T253N	Pathogenic	0.963
LRP5	O75197-1.2	T253P	Pathogenic	0.991
LRP5	O75197-1.2	T253Q	Pathogenic	0.991
LRP5	O75197-1.2	T253R	Pathogenic	0.981
LRP5	O75197-1.2	T253S	Pathogenic	0.932
LRP5	O75197-1.2	T253V	Pathogenic	0.959
LRP5	O75197-1.2	T253W	Pathogenic	0.987
LRP5	O75197-1.2	T253Y	Pathogenic	0.996
LRP5	O75197-1.2	D254A	Pathogenic	0.994
LRP5	O75197-1.2	D254C	Pathogenic	0.997
LRP5	O75197-1.2	D254E	Pathogenic	0.823
LRP5	O75197-1.2	D254F	Pathogenic	0.992
LRP5	O75197-1.2	D254G	Pathogenic	0.986
LRP5	O75197-1.2	D254H	Pathogenic	0.985
LRP5	O75197-1.2	D254I	Pathogenic	0.993
LRP5	O75197-1.2	D254K	Pathogenic	0.991
LRP5	O75197-1.2	D254L	Pathogenic	0.998
LRP5	O75197-1.2	D254M	Pathogenic	0.996
LRP5	O75197-1.2	D254N	Pathogenic	0.933
LRP5	O75197-1.2	D254P	Pathogenic	0.976
LRP5	O75197-1.2	D254Q	Pathogenic	0.967
LRP5	O75197-1.2	D254R	Pathogenic	0.997
LRP5	O75197-1.2	D254S	Pathogenic	0.962
LRP5	O75197-1.2	D254T	Pathogenic	0.984
LRP5	O75197-1.2	D254V	Pathogenic	0.996
LRP5	O75197-1.2	D254W	Pathogenic	0.996
LRP5	O75197-1.2	D254Y	Pathogenic	0.996
LRP5	O75197-1.2	W255A	Pathogenic	0.999
LRP5	O75197-1.2	W255C	Pathogenic	0.998
LRP5	O75197-1.2	W255D	Pathogenic	0.999
LRP5	O75197-1.2	W255E	Pathogenic	0.998
LRP5	O75197-1.2	W255F	Pathogenic	0.978
LRP5	O75197-1.2	W255G	Pathogenic	0.995
LRP5	O75197-1.2	W255H	Pathogenic	0.996
LRP5	O75197-1.2	W255I	Pathogenic	1.0
LRP5	O75197-1.2	W255K	Pathogenic	0.997
LRP5	O75197-1.2	W255L	Pathogenic	0.999
LRP5	O75197-1.2	W255M	Pathogenic	0.996
LRP5	O75197-1.2	W255N	Pathogenic	0.999
LRP5	O75197-1.2	W255P	Pathogenic	1.0
LRP5	O75197-1.2	W255Q	Pathogenic	0.995
LRP5	O75197-1.2	W255R	Pathogenic	0.997
LRP5	O75197-1.2	W255S	Pathogenic	0.999
LRP5	O75197-1.2	W255T	Pathogenic	0.997
LRP5	O75197-1.2	W255V	Pathogenic	1.0
LRP5	O75197-1.2	W255Y	Pathogenic	0.875
LRP5	O75197-1.2	Q256A	Neutral	0.34
LRP5	O75197-1.2	Q256C	Pathogenic	0.729
LRP5	O75197-1.2	Q256D	Neutral	0.147
LRP5	O75197-1.2	Q256E	Neutral	0.021
LRP5	O75197-1.2	Q256F	Pathogenic	0.57
LRP5	O75197-1.2	Q256G	Pathogenic	0.667
LRP5	O75197-1.2	Q256H	Neutral	0.175
LRP5	O75197-1.2	Q256I	Pathogenic	0.571
LRP5	O75197-1.2	Q256K	Neutral	0.045
LRP5	O75197-1.2	Q256L	Neutral	0.324
LRP5	O75197-1.2	Q256M	Neutral	0.073
LRP5	O75197-1.2	Q256N	Neutral	0.168
LRP5	O75197-1.2	Q256P	Neutral	0.27
LRP5	O75197-1.2	Q256R	Neutral	0.043
LRP5	O75197-1.2	Q256S	Neutral	0.189
LRP5	O75197-1.2	Q256T	Neutral	0.36
LRP5	O75197-1.2	Q256V	Neutral	0.425
LRP5	O75197-1.2	Q256W	Neutral	0.216
LRP5	O75197-1.2	Q256Y	Neutral	0.229
LRP5	O75197-1.2	T257A	Pathogenic	0.984
LRP5	O75197-1.2	T257C	Pathogenic	0.991
LRP5	O75197-1.2	T257D	Pathogenic	0.988
LRP5	O75197-1.2	T257E	Pathogenic	0.989
LRP5	O75197-1.2	T257F	Pathogenic	0.993
LRP5	O75197-1.2	T257G	Pathogenic	0.998
LRP5	O75197-1.2	T257H	Pathogenic	0.998
LRP5	O75197-1.2	T257I	Pathogenic	0.98
LRP5	O75197-1.2	T257K	Pathogenic	0.985
LRP5	O75197-1.2	T257L	Pathogenic	0.982
LRP5	O75197-1.2	T257M	Pathogenic	0.988
LRP5	O75197-1.2	T257N	Pathogenic	0.97
LRP5	O75197-1.2	T257P	Pathogenic	0.993
LRP5	O75197-1.2	T257Q	Pathogenic	0.993
LRP5	O75197-1.2	T257R	Pathogenic	0.984
LRP5	O75197-1.2	T257S	Pathogenic	0.944
LRP5	O75197-1.2	T257V	Pathogenic	0.966
LRP5	O75197-1.2	T257W	Pathogenic	0.99
LRP5	O75197-1.2	T257Y	Pathogenic	0.997
LRP5	O75197-1.2	R258A	Neutral	0.179
LRP5	O75197-1.2	R258C	Pathogenic	0.532
LRP5	O75197-1.2	R258D	Pathogenic	0.643
LRP5	O75197-1.2	R258E	Neutral	0.151
LRP5	O75197-1.2	R258F	Neutral	0.374
LRP5	O75197-1.2	R258G	Neutral	0.458
LRP5	O75197-1.2	R258H	Neutral	0.083
LRP5	O75197-1.2	R258I	Neutral	0.367
LRP5	O75197-1.2	R258K	Neutral	0.027
LRP5	O75197-1.2	R258L	Neutral	0.173
LRP5	O75197-1.2	R258M	Neutral	0.095
LRP5	O75197-1.2	R258N	Neutral	0.145
LRP5	O75197-1.2	R258P	Neutral	0.323
LRP5	O75197-1.2	R258Q	Neutral	0.039
LRP5	O75197-1.2	R258S	Neutral	0.23
LRP5	O75197-1.2	R258T	Neutral	0.192
LRP5	O75197-1.2	R258V	Neutral	0.487
LRP5	O75197-1.2	R258W	Neutral	0.283
LRP5	O75197-1.2	R258Y	Neutral	0.294
LRP5	O75197-1.2	S259A	Pathogenic	0.746
LRP5	O75197-1.2	S259C	Pathogenic	0.936
LRP5	O75197-1.2	S259D	Pathogenic	0.861
LRP5	O75197-1.2	S259E	Pathogenic	0.871
LRP5	O75197-1.2	S259F	Pathogenic	0.953
LRP5	O75197-1.2	S259G	Pathogenic	0.919
LRP5	O75197-1.2	S259H	Pathogenic	0.968
LRP5	O75197-1.2	S259I	Pathogenic	0.953
LRP5	O75197-1.2	S259K	Pathogenic	0.826
LRP5	O75197-1.2	S259L	Pathogenic	0.957
LRP5	O75197-1.2	S259M	Pathogenic	0.917
LRP5	O75197-1.2	S259N	Pathogenic	0.701
LRP5	O75197-1.2	S259P	Pathogenic	0.949
LRP5	O75197-1.2	S259Q	Pathogenic	0.907
LRP5	O75197-1.2	S259R	Pathogenic	0.933
LRP5	O75197-1.2	S259T	Pathogenic	0.75
LRP5	O75197-1.2	S259V	Pathogenic	0.972
LRP5	O75197-1.2	S259W	Pathogenic	0.975
LRP5	O75197-1.2	S259Y	Pathogenic	0.977
LRP5	O75197-1.2	I260A	Pathogenic	0.966
LRP5	O75197-1.2	I260C	Pathogenic	0.982
LRP5	O75197-1.2	I260D	Pathogenic	0.991
LRP5	O75197-1.2	I260E	Pathogenic	0.992
LRP5	O75197-1.2	I260F	Pathogenic	0.974
LRP5	O75197-1.2	I260G	Pathogenic	0.998
LRP5	O75197-1.2	I260H	Pathogenic	0.996
LRP5	O75197-1.2	I260K	Pathogenic	0.989
LRP5	O75197-1.2	I260L	Pathogenic	0.794
LRP5	O75197-1.2	I260M	Pathogenic	0.885
LRP5	O75197-1.2	I260N	Pathogenic	0.992
LRP5	O75197-1.2	I260P	Pathogenic	0.997
LRP5	O75197-1.2	I260Q	Pathogenic	0.994
LRP5	O75197-1.2	I260R	Pathogenic	0.989
LRP5	O75197-1.2	I260S	Pathogenic	0.985
LRP5	O75197-1.2	I260T	Pathogenic	0.966
LRP5	O75197-1.2	I260V	Neutral	0.444
LRP5	O75197-1.2	I260W	Pathogenic	0.999
LRP5	O75197-1.2	I260Y	Pathogenic	0.982
LRP5	O75197-1.2	H261A	Pathogenic	0.983
LRP5	O75197-1.2	H261C	Pathogenic	0.99
LRP5	O75197-1.2	H261D	Pathogenic	0.91
LRP5	O75197-1.2	H261E	Pathogenic	0.793
LRP5	O75197-1.2	H261F	Pathogenic	0.839
LRP5	O75197-1.2	H261G	Pathogenic	0.983
LRP5	O75197-1.2	H261I	Pathogenic	0.98
LRP5	O75197-1.2	H261K	Pathogenic	0.894
LRP5	O75197-1.2	H261L	Pathogenic	0.982
LRP5	O75197-1.2	H261M	Pathogenic	0.964
LRP5	O75197-1.2	H261N	Pathogenic	0.561
LRP5	O75197-1.2	H261P	Pathogenic	0.976
LRP5	O75197-1.2	H261Q	Pathogenic	0.849
LRP5	O75197-1.2	H261R	Pathogenic	0.728
LRP5	O75197-1.2	H261S	Pathogenic	0.95
LRP5	O75197-1.2	H261T	Pathogenic	0.984
LRP5	O75197-1.2	H261V	Pathogenic	0.988
LRP5	O75197-1.2	H261W	Pathogenic	0.909
LRP5	O75197-1.2	H261Y	Neutral	0.278
LRP5	O75197-1.2	A262C	Neutral	0.449
LRP5	O75197-1.2	A262D	Pathogenic	0.839
LRP5	O75197-1.2	A262E	Pathogenic	0.652
LRP5	O75197-1.2	A262F	Pathogenic	0.772
LRP5	O75197-1.2	A262G	Pathogenic	0.53
LRP5	O75197-1.2	A262H	Pathogenic	0.918
LRP5	O75197-1.2	A262I	Pathogenic	0.528
LRP5	O75197-1.2	A262K	Pathogenic	0.567
LRP5	O75197-1.2	A262L	Pathogenic	0.551
LRP5	O75197-1.2	A262M	Pathogenic	0.651
LRP5	O75197-1.2	A262N	Pathogenic	0.857
LRP5	O75197-1.2	A262P	Pathogenic	0.757
LRP5	O75197-1.2	A262Q	Pathogenic	0.73
LRP5	O75197-1.2	A262R	Pathogenic	0.559
LRP5	O75197-1.2	A262S	Neutral	0.268
LRP5	O75197-1.2	A262T	Pathogenic	0.584
LRP5	O75197-1.2	A262V	Neutral	0.39
LRP5	O75197-1.2	A262W	Pathogenic	0.867
LRP5	O75197-1.2	A262Y	Pathogenic	0.876
LRP5	O75197-1.2	C263A	Pathogenic	0.939
LRP5	O75197-1.2	C263D	Pathogenic	0.994
LRP5	O75197-1.2	C263E	Pathogenic	0.998
LRP5	O75197-1.2	C263F	Pathogenic	0.992
LRP5	O75197-1.2	C263G	Pathogenic	0.997
LRP5	O75197-1.2	C263H	Pathogenic	0.997
LRP5	O75197-1.2	C263I	Pathogenic	0.976
LRP5	O75197-1.2	C263K	Pathogenic	0.992
LRP5	O75197-1.2	C263L	Pathogenic	0.978
LRP5	O75197-1.2	C263M	Pathogenic	0.985
LRP5	O75197-1.2	C263N	Pathogenic	0.995
LRP5	O75197-1.2	C263P	Pathogenic	0.998
LRP5	O75197-1.2	C263Q	Pathogenic	0.996
LRP5	O75197-1.2	C263R	Pathogenic	0.992
LRP5	O75197-1.2	C263S	Pathogenic	0.972
LRP5	O75197-1.2	C263T	Pathogenic	0.979
LRP5	O75197-1.2	C263V	Pathogenic	0.986
LRP5	O75197-1.2	C263W	Pathogenic	0.987
LRP5	O75197-1.2	C263Y	Pathogenic	0.996
LRP5	O75197-1.2	N264A	Pathogenic	0.808
LRP5	O75197-1.2	N264C	Pathogenic	0.879
LRP5	O75197-1.2	N264D	Neutral	0.232
LRP5	O75197-1.2	N264E	Pathogenic	0.505
LRP5	O75197-1.2	N264F	Pathogenic	0.771
LRP5	O75197-1.2	N264G	Neutral	0.368
LRP5	O75197-1.2	N264H	Neutral	0.151
LRP5	O75197-1.2	N264I	Pathogenic	0.771
LRP5	O75197-1.2	N264K	Neutral	0.417
LRP5	O75197-1.2	N264L	Pathogenic	0.787
LRP5	O75197-1.2	N264M	Pathogenic	0.649
LRP5	O75197-1.2	N264P	Pathogenic	0.752
LRP5	O75197-1.2	N264Q	Neutral	0.427
LRP5	O75197-1.2	N264R	Neutral	0.409
LRP5	O75197-1.2	N264S	Neutral	0.171
LRP5	O75197-1.2	N264T	Neutral	0.332
LRP5	O75197-1.2	N264V	Pathogenic	0.855
LRP5	O75197-1.2	N264W	Pathogenic	0.866
LRP5	O75197-1.2	N264Y	Pathogenic	0.697
LRP5	O75197-1.2	K265A	Pathogenic	0.959
LRP5	O75197-1.2	K265C	Pathogenic	0.992
LRP5	O75197-1.2	K265D	Pathogenic	0.985
LRP5	O75197-1.2	K265E	Pathogenic	0.864
LRP5	O75197-1.2	K265F	Pathogenic	0.985
LRP5	O75197-1.2	K265G	Pathogenic	0.989
LRP5	O75197-1.2	K265H	Pathogenic	0.968
LRP5	O75197-1.2	K265I	Pathogenic	0.984
LRP5	O75197-1.2	K265L	Pathogenic	0.958
LRP5	O75197-1.2	K265M	Pathogenic	0.919
LRP5	O75197-1.2	K265N	Pathogenic	0.948
LRP5	O75197-1.2	K265P	Pathogenic	0.944
LRP5	O75197-1.2	K265Q	Pathogenic	0.815
LRP5	O75197-1.2	K265R	Pathogenic	0.742
LRP5	O75197-1.2	K265S	Pathogenic	0.914
LRP5	O75197-1.2	K265T	Pathogenic	0.963
LRP5	O75197-1.2	K265V	Pathogenic	0.971
LRP5	O75197-1.2	K265W	Pathogenic	0.976
LRP5	O75197-1.2	K265Y	Pathogenic	0.978
LRP5	O75197-1.2	R266A	Neutral	0.014
LRP5	O75197-1.2	R266C	Neutral	0.067
LRP5	O75197-1.2	R266D	Neutral	0.102
LRP5	O75197-1.2	R266E	Neutral	0.011
LRP5	O75197-1.2	R266F	Neutral	0.036
LRP5	O75197-1.2	R266G	Neutral	0.051
LRP5	O75197-1.2	R266H	Neutral	0.006
LRP5	O75197-1.2	R266I	Neutral	0.035
LRP5	O75197-1.2	R266K	Neutral	0.002
LRP5	O75197-1.2	R266L	Neutral	0.013
LRP5	O75197-1.2	R266M	Neutral	0.007
LRP5	O75197-1.2	R266N	Neutral	0.011
LRP5	O75197-1.2	R266P	Neutral	0.029
LRP5	O75197-1.2	R266Q	Neutral	0.003
LRP5	O75197-1.2	R266S	Neutral	0.019
LRP5	O75197-1.2	R266T	Neutral	0.015
LRP5	O75197-1.2	R266V	Neutral	0.057
LRP5	O75197-1.2	R266W	Neutral	0.024
LRP5	O75197-1.2	R266Y	Neutral	0.026
LRP5	O75197-1.2	T267A	Pathogenic	0.572
LRP5	O75197-1.2	T267C	Pathogenic	0.697
LRP5	O75197-1.2	T267D	Pathogenic	0.639
LRP5	O75197-1.2	T267E	Pathogenic	0.661
LRP5	O75197-1.2	T267F	Pathogenic	0.763
LRP5	O75197-1.2	T267G	Pathogenic	0.909
LRP5	O75197-1.2	T267H	Pathogenic	0.921
LRP5	O75197-1.2	T267I	Pathogenic	0.515
LRP5	O75197-1.2	T267K	Pathogenic	0.577
LRP5	O75197-1.2	T267L	Pathogenic	0.538
LRP5	O75197-1.2	T267M	Pathogenic	0.639
LRP5	O75197-1.2	T267N	Neutral	0.403
LRP5	O75197-1.2	T267P	Pathogenic	0.745
LRP5	O75197-1.2	T267Q	Pathogenic	0.737
LRP5	O75197-1.2	T267R	Pathogenic	0.568
LRP5	O75197-1.2	T267S	Neutral	0.263
LRP5	O75197-1.2	T267V	Neutral	0.378
LRP5	O75197-1.2	T267W	Pathogenic	0.67
LRP5	O75197-1.2	T267Y	Pathogenic	0.87
LRP5	O75197-1.2	G268A	Pathogenic	0.862
LRP5	O75197-1.2	G268C	Pathogenic	0.989
LRP5	O75197-1.2	G268D	Pathogenic	0.923
LRP5	O75197-1.2	G268E	Pathogenic	0.976
LRP5	O75197-1.2	G268F	Pathogenic	0.977
LRP5	O75197-1.2	G268H	Pathogenic	0.984
LRP5	O75197-1.2	G268I	Pathogenic	0.992
LRP5	O75197-1.2	G268K	Pathogenic	0.966
LRP5	O75197-1.2	G268L	Pathogenic	0.993
LRP5	O75197-1.2	G268M	Pathogenic	0.986
LRP5	O75197-1.2	G268N	Pathogenic	0.821
LRP5	O75197-1.2	G268P	Pathogenic	0.975
LRP5	O75197-1.2	G268Q	Pathogenic	0.983
LRP5	O75197-1.2	G268R	Pathogenic	0.964
LRP5	O75197-1.2	G268S	Pathogenic	0.887
LRP5	O75197-1.2	G268T	Pathogenic	0.983
LRP5	O75197-1.2	G268V	Pathogenic	0.987
LRP5	O75197-1.2	G268W	Pathogenic	0.897
LRP5	O75197-1.2	G268Y	Pathogenic	0.989
LRP5	O75197-1.2	G269A	Neutral	0.003
LRP5	O75197-1.2	G269C	Neutral	0.041
LRP5	O75197-1.2	G269D	Neutral	0.005
LRP5	O75197-1.2	G269E	Neutral	0.018
LRP5	O75197-1.2	G269F	Neutral	0.019
LRP5	O75197-1.2	G269H	Neutral	0.027
LRP5	O75197-1.2	G269I	Neutral	0.055
LRP5	O75197-1.2	G269K	Neutral	0.013
LRP5	O75197-1.2	G269L	Neutral	0.06
LRP5	O75197-1.2	G269M	Neutral	0.031
LRP5	O75197-1.2	G269N	Neutral	0.002
LRP5	O75197-1.2	G269P	Neutral	0.017
LRP5	O75197-1.2	G269Q	Neutral	0.026
LRP5	O75197-1.2	G269R	Neutral	0.012
LRP5	O75197-1.2	G269S	Neutral	0.004
LRP5	O75197-1.2	G269T	Neutral	0.026
LRP5	O75197-1.2	G269V	Neutral	0.032
LRP5	O75197-1.2	G269W	Neutral	0.004
LRP5	O75197-1.2	G269Y	Neutral	0.038
LRP5	O75197-1.2	K270A	Neutral	0.036
LRP5	O75197-1.2	K270C	Neutral	0.163
LRP5	O75197-1.2	K270D	Neutral	0.092
LRP5	O75197-1.2	K270E	Neutral	0.01
LRP5	O75197-1.2	K270F	Neutral	0.093
LRP5	O75197-1.2	K270G	Neutral	0.127
LRP5	O75197-1.2	K270H	Neutral	0.045
LRP5	O75197-1.2	K270I	Neutral	0.09
LRP5	O75197-1.2	K270L	Neutral	0.035
LRP5	O75197-1.2	K270M	Neutral	0.018
LRP5	O75197-1.2	K270N	Neutral	0.028
LRP5	O75197-1.2	K270P	Neutral	0.026
LRP5	O75197-1.2	K270Q	Neutral	0.007
LRP5	O75197-1.2	K270R	Neutral	0.005
LRP5	O75197-1.2	K270S	Neutral	0.017
LRP5	O75197-1.2	K270T	Neutral	0.039
LRP5	O75197-1.2	K270V	Neutral	0.051
LRP5	O75197-1.2	K270W	Neutral	0.061
LRP5	O75197-1.2	K270Y	Neutral	0.065
LRP5	O75197-1.2	R271A	Neutral	0.03
LRP5	O75197-1.2	R271C	Neutral	0.138
LRP5	O75197-1.2	R271D	Neutral	0.203
LRP5	O75197-1.2	R271E	Neutral	0.025
LRP5	O75197-1.2	R271F	Neutral	0.078
LRP5	O75197-1.2	R271G	Neutral	0.107
LRP5	O75197-1.2	R271H	Neutral	0.013
LRP5	O75197-1.2	R271I	Neutral	0.076
LRP5	O75197-1.2	R271K	Neutral	0.004
LRP5	O75197-1.2	R271L	Neutral	0.029
LRP5	O75197-1.2	R271M	Neutral	0.015
LRP5	O75197-1.2	R271N	Neutral	0.023
LRP5	O75197-1.2	R271P	Neutral	0.063
LRP5	O75197-1.2	R271Q	Neutral	0.006
LRP5	O75197-1.2	R271S	Neutral	0.041
LRP5	O75197-1.2	R271T	Neutral	0.033
LRP5	O75197-1.2	R271V	Neutral	0.118
LRP5	O75197-1.2	R271W	Neutral	0.053
LRP5	O75197-1.2	R271Y	Neutral	0.056
LRP5	O75197-1.2	K272A	Neutral	0.219
LRP5	O75197-1.2	K272C	Pathogenic	0.594
LRP5	O75197-1.2	K272D	Neutral	0.433
LRP5	O75197-1.2	K272E	Neutral	0.07
LRP5	O75197-1.2	K272F	Neutral	0.435
LRP5	O75197-1.2	K272G	Pathogenic	0.522
LRP5	O75197-1.2	K272H	Neutral	0.263
LRP5	O75197-1.2	K272I	Neutral	0.428
LRP5	O75197-1.2	K272L	Neutral	0.212
LRP5	O75197-1.2	K272M	Neutral	0.119
LRP5	O75197-1.2	K272N	Neutral	0.179
LRP5	O75197-1.2	K272P	Neutral	0.168
LRP5	O75197-1.2	K272Q	Neutral	0.05
LRP5	O75197-1.2	K272R	Neutral	0.033
LRP5	O75197-1.2	K272S	Neutral	0.113
LRP5	O75197-1.2	K272T	Neutral	0.235
LRP5	O75197-1.2	K272V	Neutral	0.287
LRP5	O75197-1.2	K272W	Neutral	0.328
LRP5	O75197-1.2	K272Y	Neutral	0.345
LRP5	O75197-1.2	E273A	Pathogenic	0.836
LRP5	O75197-1.2	E273C	Pathogenic	0.988
LRP5	O75197-1.2	E273D	Neutral	0.28
LRP5	O75197-1.2	E273F	Pathogenic	0.928
LRP5	O75197-1.2	E273G	Pathogenic	0.952
LRP5	O75197-1.2	E273H	Pathogenic	0.674
LRP5	O75197-1.2	E273I	Pathogenic	0.928
LRP5	O75197-1.2	E273K	Neutral	0.49
LRP5	O75197-1.2	E273L	Pathogenic	0.934
LRP5	O75197-1.2	E273M	Pathogenic	0.876
LRP5	O75197-1.2	E273N	Pathogenic	0.798
LRP5	O75197-1.2	E273P	Pathogenic	0.785
LRP5	O75197-1.2	E273Q	Neutral	0.235
LRP5	O75197-1.2	E273R	Pathogenic	0.738
LRP5	O75197-1.2	E273S	Pathogenic	0.697
LRP5	O75197-1.2	E273T	Pathogenic	0.848
LRP5	O75197-1.2	E273V	Pathogenic	0.88
LRP5	O75197-1.2	E273W	Pathogenic	0.891
LRP5	O75197-1.2	E273Y	Pathogenic	0.898
LRP5	O75197-1.2	I274A	Pathogenic	0.629
LRP5	O75197-1.2	I274C	Pathogenic	0.762
LRP5	O75197-1.2	I274D	Pathogenic	0.862
LRP5	O75197-1.2	I274E	Pathogenic	0.878
LRP5	O75197-1.2	I274F	Pathogenic	0.693
LRP5	O75197-1.2	I274G	Pathogenic	0.972
LRP5	O75197-1.2	I274H	Pathogenic	0.936
LRP5	O75197-1.2	I274K	Pathogenic	0.841
LRP5	O75197-1.2	I274L	Neutral	0.187
LRP5	O75197-1.2	I274M	Neutral	0.315
LRP5	O75197-1.2	I274N	Pathogenic	0.88
LRP5	O75197-1.2	I274P	Pathogenic	0.959
LRP5	O75197-1.2	I274Q	Pathogenic	0.914
LRP5	O75197-1.2	I274R	Pathogenic	0.837
LRP5	O75197-1.2	I274S	Pathogenic	0.793
LRP5	O75197-1.2	I274T	Pathogenic	0.628
LRP5	O75197-1.2	I274V	Neutral	0.045
LRP5	O75197-1.2	I274W	Pathogenic	0.976
LRP5	O75197-1.2	I274Y	Pathogenic	0.764
LRP5	O75197-1.2	L275A	Neutral	0.152
LRP5	O75197-1.2	L275C	Neutral	0.252
LRP5	O75197-1.2	L275D	Pathogenic	0.666
LRP5	O75197-1.2	L275E	Neutral	0.432
LRP5	O75197-1.2	L275F	Neutral	0.169
LRP5	O75197-1.2	L275G	Pathogenic	0.788
LRP5	O75197-1.2	L275H	Pathogenic	0.605
LRP5	O75197-1.2	L275I	Neutral	0.022
LRP5	O75197-1.2	L275K	Neutral	0.155
LRP5	O75197-1.2	L275M	Neutral	0.016
LRP5	O75197-1.2	L275N	Neutral	0.435
LRP5	O75197-1.2	L275P	Pathogenic	0.713
LRP5	O75197-1.2	L275Q	Neutral	0.268
LRP5	O75197-1.2	L275R	Neutral	0.151
LRP5	O75197-1.2	L275S	Neutral	0.288
LRP5	O75197-1.2	L275T	Neutral	0.151
LRP5	O75197-1.2	L275V	Neutral	0.044
LRP5	O75197-1.2	L275W	Pathogenic	0.543
LRP5	O75197-1.2	L275Y	Neutral	0.255
LRP5	O75197-1.2	S276A	Neutral	0.11
LRP5	O75197-1.2	S276C	Neutral	0.383
LRP5	O75197-1.2	S276D	Neutral	0.207
LRP5	O75197-1.2	S276E	Neutral	0.222
LRP5	O75197-1.2	S276F	Neutral	0.459
LRP5	O75197-1.2	S276G	Neutral	0.325
LRP5	O75197-1.2	S276H	Pathogenic	0.558
LRP5	O75197-1.2	S276I	Neutral	0.46
LRP5	O75197-1.2	S276K	Neutral	0.167
LRP5	O75197-1.2	S276L	Neutral	0.483
LRP5	O75197-1.2	S276M	Neutral	0.319
LRP5	O75197-1.2	S276N	Neutral	0.09
LRP5	O75197-1.2	S276P	Neutral	0.439
LRP5	O75197-1.2	S276Q	Neutral	0.292
LRP5	O75197-1.2	S276R	Neutral	0.371
LRP5	O75197-1.2	S276T	Neutral	0.113
LRP5	O75197-1.2	S276V	Pathogenic	0.598
LRP5	O75197-1.2	S276W	Pathogenic	0.62
LRP5	O75197-1.2	S276Y	Pathogenic	0.638
LRP5	O75197-1.2	A277C	Neutral	0.021
LRP5	O75197-1.2	A277D	Neutral	0.119
LRP5	O75197-1.2	A277E	Neutral	0.046
LRP5	O75197-1.2	A277F	Neutral	0.081
LRP5	O75197-1.2	A277G	Neutral	0.028
LRP5	O75197-1.2	A277H	Neutral	0.224
LRP5	O75197-1.2	A277I	Neutral	0.028
LRP5	O75197-1.2	A277K	Neutral	0.033
LRP5	O75197-1.2	A277L	Neutral	0.031
LRP5	O75197-1.2	A277M	Neutral	0.046
LRP5	O75197-1.2	A277N	Neutral	0.135
LRP5	O75197-1.2	A277P	Neutral	0.075
LRP5	O75197-1.2	A277Q	Neutral	0.065
LRP5	O75197-1.2	A277R	Neutral	0.032
LRP5	O75197-1.2	A277S	Neutral	0.009
LRP5	O75197-1.2	A277T	Neutral	0.035
LRP5	O75197-1.2	A277V	Neutral	0.016
LRP5	O75197-1.2	A277W	Neutral	0.144
LRP5	O75197-1.2	A277Y	Neutral	0.154
LRP5	O75197-1.2	L278A	Neutral	0.068
LRP5	O75197-1.2	L278C	Neutral	0.122
LRP5	O75197-1.2	L278D	Neutral	0.45
LRP5	O75197-1.2	L278E	Neutral	0.238
LRP5	O75197-1.2	L278F	Neutral	0.077
LRP5	O75197-1.2	L278G	Pathogenic	0.604
LRP5	O75197-1.2	L278H	Neutral	0.386
LRP5	O75197-1.2	L278I	Neutral	0.009
LRP5	O75197-1.2	L278K	Neutral	0.07
LRP5	O75197-1.2	L278M	Neutral	0.006
LRP5	O75197-1.2	L278N	Neutral	0.24
LRP5	O75197-1.2	L278P	Pathogenic	0.504
LRP5	O75197-1.2	L278Q	Neutral	0.131
LRP5	O75197-1.2	L278R	Neutral	0.068
LRP5	O75197-1.2	L278S	Neutral	0.142
LRP5	O75197-1.2	L278T	Neutral	0.068
LRP5	O75197-1.2	L278V	Neutral	0.019
LRP5	O75197-1.2	L278W	Neutral	0.328
LRP5	O75197-1.2	L278Y	Neutral	0.123
LRP5	O75197-1.2	Y279A	Pathogenic	0.875
LRP5	O75197-1.2	Y279C	Pathogenic	0.927
LRP5	O75197-1.2	Y279D	Pathogenic	0.894
LRP5	O75197-1.2	Y279E	Pathogenic	0.763
LRP5	O75197-1.2	Y279F	Neutral	0.025
LRP5	O75197-1.2	Y279G	Pathogenic	0.94
LRP5	O75197-1.2	Y279H	Neutral	0.071
LRP5	O75197-1.2	Y279I	Pathogenic	0.68
LRP5	O75197-1.2	Y279K	Pathogenic	0.71
LRP5	O75197-1.2	Y279L	Pathogenic	0.7
LRP5	O75197-1.2	Y279M	Pathogenic	0.78
LRP5	O75197-1.2	Y279N	Pathogenic	0.765
LRP5	O75197-1.2	Y279P	Pathogenic	0.97
LRP5	O75197-1.2	Y279Q	Pathogenic	0.608
LRP5	O75197-1.2	Y279R	Pathogenic	0.707
LRP5	O75197-1.2	Y279S	Pathogenic	0.839
LRP5	O75197-1.2	Y279T	Pathogenic	0.875
LRP5	O75197-1.2	Y279V	Pathogenic	0.777
LRP5	O75197-1.2	Y279W	Neutral	0.048
LRP5	O75197-1.2	S280A	Neutral	0.468
LRP5	O75197-1.2	S280C	Pathogenic	0.815
LRP5	O75197-1.2	S280D	Pathogenic	0.65
LRP5	O75197-1.2	S280E	Pathogenic	0.67
LRP5	O75197-1.2	S280F	Pathogenic	0.858
LRP5	O75197-1.2	S280G	Pathogenic	0.774
LRP5	O75197-1.2	S280H	Pathogenic	0.9
LRP5	O75197-1.2	S280I	Pathogenic	0.858
LRP5	O75197-1.2	S280K	Pathogenic	0.587
LRP5	O75197-1.2	S280L	Pathogenic	0.869
LRP5	O75197-1.2	S280M	Pathogenic	0.769
LRP5	O75197-1.2	S280N	Neutral	0.413
LRP5	O75197-1.2	S280P	Pathogenic	0.847
LRP5	O75197-1.2	S280Q	Pathogenic	0.745
LRP5	O75197-1.2	S280R	Pathogenic	0.807
LRP5	O75197-1.2	S280T	Neutral	0.474
LRP5	O75197-1.2	S280V	Pathogenic	0.913
LRP5	O75197-1.2	S280W	Pathogenic	0.921
LRP5	O75197-1.2	S280Y	Pathogenic	0.926
LRP5	O75197-1.2	P281A	Pathogenic	0.992
LRP5	O75197-1.2	P281C	Pathogenic	0.999
LRP5	O75197-1.2	P281D	Pathogenic	0.98
LRP5	O75197-1.2	P281E	Pathogenic	0.982
LRP5	O75197-1.2	P281F	Pathogenic	0.999
LRP5	O75197-1.2	P281G	Pathogenic	0.996
LRP5	O75197-1.2	P281H	Pathogenic	0.997
LRP5	O75197-1.2	P281I	Pathogenic	0.998
LRP5	O75197-1.2	P281K	Pathogenic	0.974
LRP5	O75197-1.2	P281L	Pathogenic	0.999
LRP5	O75197-1.2	P281M	Pathogenic	0.997
LRP5	O75197-1.2	P281N	Pathogenic	0.994
LRP5	O75197-1.2	P281Q	Pathogenic	0.987
LRP5	O75197-1.2	P281R	Pathogenic	0.991
LRP5	O75197-1.2	P281S	Pathogenic	0.989
LRP5	O75197-1.2	P281T	Pathogenic	0.992
LRP5	O75197-1.2	P281V	Pathogenic	0.997
LRP5	O75197-1.2	P281W	Pathogenic	0.999
LRP5	O75197-1.2	P281Y	Pathogenic	0.999
LRP5	O75197-1.2	M282A	Pathogenic	0.987
LRP5	O75197-1.2	M282C	Pathogenic	0.993
LRP5	O75197-1.2	M282D	Pathogenic	0.996
LRP5	O75197-1.2	M282E	Pathogenic	0.99
LRP5	O75197-1.2	M282F	Pathogenic	0.973
LRP5	O75197-1.2	M282G	Pathogenic	0.998
LRP5	O75197-1.2	M282H	Pathogenic	0.995
LRP5	O75197-1.2	M282I	Pathogenic	0.923
LRP5	O75197-1.2	M282K	Pathogenic	0.961
LRP5	O75197-1.2	M282L	Pathogenic	0.811
LRP5	O75197-1.2	M282N	Pathogenic	0.99
LRP5	O75197-1.2	M282P	Pathogenic	0.997
LRP5	O75197-1.2	M282Q	Pathogenic	0.942
LRP5	O75197-1.2	M282R	Pathogenic	0.96
LRP5	O75197-1.2	M282S	Pathogenic	0.982
LRP5	O75197-1.2	M282T	Pathogenic	0.987
LRP5	O75197-1.2	M282V	Pathogenic	0.95
LRP5	O75197-1.2	M282W	Pathogenic	0.986
LRP5	O75197-1.2	M282Y	Pathogenic	0.993
LRP5	O75197-1.2	D283A	Pathogenic	0.988
LRP5	O75197-1.2	D283C	Pathogenic	0.993
LRP5	O75197-1.2	D283E	Pathogenic	0.702
LRP5	O75197-1.2	D283F	Pathogenic	0.985
LRP5	O75197-1.2	D283G	Pathogenic	0.973
LRP5	O75197-1.2	D283H	Pathogenic	0.97
LRP5	O75197-1.2	D283I	Pathogenic	0.985
LRP5	O75197-1.2	D283K	Pathogenic	0.983
LRP5	O75197-1.2	D283L	Pathogenic	0.996
LRP5	O75197-1.2	D283M	Pathogenic	0.991
LRP5	O75197-1.2	D283N	Pathogenic	0.876
LRP5	O75197-1.2	D283P	Pathogenic	0.953
LRP5	O75197-1.2	D283Q	Pathogenic	0.937
LRP5	O75197-1.2	D283R	Pathogenic	0.994
LRP5	O75197-1.2	D283S	Pathogenic	0.927
LRP5	O75197-1.2	D283T	Pathogenic	0.968
LRP5	O75197-1.2	D283V	Pathogenic	0.992
LRP5	O75197-1.2	D283W	Pathogenic	0.992
LRP5	O75197-1.2	D283Y	Pathogenic	0.993
LRP5	O75197-1.2	I284A	Pathogenic	0.97
LRP5	O75197-1.2	I284C	Pathogenic	0.984
LRP5	O75197-1.2	I284D	Pathogenic	0.992
LRP5	O75197-1.2	I284E	Pathogenic	0.993
LRP5	O75197-1.2	I284F	Pathogenic	0.978
LRP5	O75197-1.2	I284G	Pathogenic	0.999
LRP5	O75197-1.2	I284H	Pathogenic	0.996
LRP5	O75197-1.2	I284K	Pathogenic	0.99
LRP5	O75197-1.2	I284L	Pathogenic	0.816
LRP5	O75197-1.2	I284M	Pathogenic	0.898
LRP5	O75197-1.2	I284N	Pathogenic	0.993
LRP5	O75197-1.2	I284P	Pathogenic	0.998
LRP5	O75197-1.2	I284Q	Pathogenic	0.995
LRP5	O75197-1.2	I284R	Pathogenic	0.99
LRP5	O75197-1.2	I284S	Pathogenic	0.987
LRP5	O75197-1.2	I284T	Pathogenic	0.97
LRP5	O75197-1.2	I284V	Neutral	0.478
LRP5	O75197-1.2	I284W	Pathogenic	0.999
LRP5	O75197-1.2	I284Y	Pathogenic	0.984
LRP5	O75197-1.2	Q285A	Pathogenic	0.605
LRP5	O75197-1.2	Q285C	Pathogenic	0.889
LRP5	O75197-1.2	Q285D	Neutral	0.339
LRP5	O75197-1.2	Q285E	Neutral	0.06
LRP5	O75197-1.2	Q285F	Pathogenic	0.797
LRP5	O75197-1.2	Q285G	Pathogenic	0.856
LRP5	O75197-1.2	Q285H	Neutral	0.387
LRP5	O75197-1.2	Q285I	Pathogenic	0.798
LRP5	O75197-1.2	Q285K	Neutral	0.122
LRP5	O75197-1.2	Q285L	Pathogenic	0.587
LRP5	O75197-1.2	Q285M	Neutral	0.189
LRP5	O75197-1.2	Q285N	Neutral	0.375
LRP5	O75197-1.2	Q285P	Pathogenic	0.524
LRP5	O75197-1.2	Q285R	Neutral	0.118
LRP5	O75197-1.2	Q285S	Neutral	0.408
LRP5	O75197-1.2	Q285T	Pathogenic	0.625
LRP5	O75197-1.2	Q285V	Pathogenic	0.687
LRP5	O75197-1.2	Q285W	Neutral	0.449
LRP5	O75197-1.2	Q285Y	Neutral	0.468
LRP5	O75197-1.2	V286A	Pathogenic	0.617
LRP5	O75197-1.2	V286C	Pathogenic	0.902
LRP5	O75197-1.2	V286D	Pathogenic	0.947
LRP5	O75197-1.2	V286E	Pathogenic	0.871
LRP5	O75197-1.2	V286F	Pathogenic	0.871
LRP5	O75197-1.2	V286G	Pathogenic	0.971
LRP5	O75197-1.2	V286H	Pathogenic	0.976
LRP5	O75197-1.2	V286I	Neutral	0.073
LRP5	O75197-1.2	V286K	Pathogenic	0.826
LRP5	O75197-1.2	V286L	Neutral	0.444
LRP5	O75197-1.2	V286M	Pathogenic	0.549
LRP5	O75197-1.2	V286N	Pathogenic	0.955
LRP5	O75197-1.2	V286P	Pathogenic	0.957
LRP5	O75197-1.2	V286Q	Pathogenic	0.907
LRP5	O75197-1.2	V286R	Pathogenic	0.933
LRP5	O75197-1.2	V286S	Pathogenic	0.917
LRP5	O75197-1.2	V286T	Pathogenic	0.616
LRP5	O75197-1.2	V286W	Pathogenic	0.975
LRP5	O75197-1.2	V286Y	Pathogenic	0.898
LRP5	O75197-1.2	L287A	Neutral	0.084
LRP5	O75197-1.2	L287C	Neutral	0.147
LRP5	O75197-1.2	L287D	Pathogenic	0.505
LRP5	O75197-1.2	L287E	Neutral	0.28
LRP5	O75197-1.2	L287F	Neutral	0.094
LRP5	O75197-1.2	L287G	Pathogenic	0.655
LRP5	O75197-1.2	L287H	Neutral	0.44
LRP5	O75197-1.2	L287I	Neutral	0.011
LRP5	O75197-1.2	L287K	Neutral	0.086
LRP5	O75197-1.2	L287M	Neutral	0.008
LRP5	O75197-1.2	L287N	Neutral	0.282
LRP5	O75197-1.2	L287P	Pathogenic	0.559
LRP5	O75197-1.2	L287Q	Neutral	0.158
LRP5	O75197-1.2	L287R	Neutral	0.083
LRP5	O75197-1.2	L287S	Neutral	0.171
LRP5	O75197-1.2	L287T	Neutral	0.083
LRP5	O75197-1.2	L287V	Neutral	0.023
LRP5	O75197-1.2	L287W	Neutral	0.378
LRP5	O75197-1.2	L287Y	Neutral	0.149
LRP5	O75197-1.2	S288A	Neutral	0.099
LRP5	O75197-1.2	S288C	Neutral	0.354
LRP5	O75197-1.2	S288D	Neutral	0.188
LRP5	O75197-1.2	S288E	Neutral	0.202
LRP5	O75197-1.2	S288F	Neutral	0.429
LRP5	O75197-1.2	S288G	Neutral	0.299
LRP5	O75197-1.2	S288H	Pathogenic	0.527
LRP5	O75197-1.2	S288I	Neutral	0.43
LRP5	O75197-1.2	S288K	Neutral	0.15
LRP5	O75197-1.2	S288L	Neutral	0.452
LRP5	O75197-1.2	S288M	Neutral	0.292
LRP5	O75197-1.2	S288N	Neutral	0.081
LRP5	O75197-1.2	S288P	Neutral	0.408
LRP5	O75197-1.2	S288Q	Neutral	0.267
LRP5	O75197-1.2	S288R	Neutral	0.342
LRP5	O75197-1.2	S288T	Neutral	0.101
LRP5	O75197-1.2	S288V	Pathogenic	0.568
LRP5	O75197-1.2	S288W	Pathogenic	0.591
LRP5	O75197-1.2	S288Y	Pathogenic	0.609
LRP5	O75197-1.2	Q289A	Neutral	0.0
LRP5	O75197-1.2	Q289C	Neutral	0.002
LRP5	O75197-1.2	Q289D	Neutral	0.0
LRP5	O75197-1.2	Q289E	Neutral	0.0
LRP5	O75197-1.2	Q289F	Neutral	0.001
LRP5	O75197-1.2	Q289G	Neutral	0.001
LRP5	O75197-1.2	Q289H	Neutral	0.0
LRP5	O75197-1.2	Q289I	Neutral	0.001
LRP5	O75197-1.2	Q289K	Neutral	0.0
LRP5	O75197-1.2	Q289L	Neutral	0.0
LRP5	O75197-1.2	Q289M	Neutral	0.0
LRP5	O75197-1.2	Q289N	Neutral	0.0
LRP5	O75197-1.2	Q289P	Neutral	0.0
LRP5	O75197-1.2	Q289R	Neutral	0.0
LRP5	O75197-1.2	Q289S	Neutral	0.0
LRP5	O75197-1.2	Q289T	Neutral	0.0
LRP5	O75197-1.2	Q289V	Neutral	0.0
LRP5	O75197-1.2	Q289W	Neutral	0.0
LRP5	O75197-1.2	Q289Y	Neutral	0.0
LRP5	O75197-1.2	E290A	Neutral	0.0
LRP5	O75197-1.2	E290C	Neutral	0.0
LRP5	O75197-1.2	E290D	Neutral	0.0
LRP5	O75197-1.2	E290F	Neutral	0.0
LRP5	O75197-1.2	E290G	Neutral	0.0
LRP5	O75197-1.2	E290H	Neutral	0.0
LRP5	O75197-1.2	E290I	Neutral	0.0
LRP5	O75197-1.2	E290K	Neutral	0.0
LRP5	O75197-1.2	E290L	Neutral	0.0
LRP5	O75197-1.2	E290M	Neutral	0.0
LRP5	O75197-1.2	E290N	Neutral	0.0
LRP5	O75197-1.2	E290P	Neutral	0.0
LRP5	O75197-1.2	E290Q	Neutral	0.0
LRP5	O75197-1.2	E290R	Neutral	0.0
LRP5	O75197-1.2	E290S	Neutral	0.0
LRP5	O75197-1.2	E290T	Neutral	0.0
LRP5	O75197-1.2	E290V	Neutral	0.0
LRP5	O75197-1.2	E290W	Neutral	0.0
LRP5	O75197-1.2	E290Y	Neutral	0.0
LRP5	O75197-1.2	R291A	Neutral	0.072
LRP5	O75197-1.2	R291C	Neutral	0.289
LRP5	O75197-1.2	R291D	Neutral	0.392
LRP5	O75197-1.2	R291E	Neutral	0.06
LRP5	O75197-1.2	R291F	Neutral	0.176
LRP5	O75197-1.2	R291G	Neutral	0.232
LRP5	O75197-1.2	R291H	Neutral	0.032
LRP5	O75197-1.2	R291I	Neutral	0.172
LRP5	O75197-1.2	R291K	Neutral	0.01
LRP5	O75197-1.2	R291L	Neutral	0.07
LRP5	O75197-1.2	R291M	Neutral	0.036
LRP5	O75197-1.2	R291N	Neutral	0.057
LRP5	O75197-1.2	R291P	Neutral	0.146
LRP5	O75197-1.2	R291Q	Neutral	0.014
LRP5	O75197-1.2	R291S	Neutral	0.097
LRP5	O75197-1.2	R291T	Neutral	0.078
LRP5	O75197-1.2	R291V	Neutral	0.254
LRP5	O75197-1.2	R291W	Neutral	0.124
LRP5	O75197-1.2	R291Y	Neutral	0.13
LRP5	O75197-1.2	Q292A	Neutral	0.272
LRP5	O75197-1.2	Q292C	Pathogenic	0.662
LRP5	O75197-1.2	Q292D	Neutral	0.111
LRP5	O75197-1.2	Q292E	Neutral	0.015
LRP5	O75197-1.2	Q292F	Neutral	0.49
LRP5	O75197-1.2	Q292G	Pathogenic	0.593
LRP5	O75197-1.2	Q292H	Neutral	0.134
LRP5	O75197-1.2	Q292I	Neutral	0.491
LRP5	O75197-1.2	Q292K	Neutral	0.033
LRP5	O75197-1.2	Q292L	Neutral	0.258
LRP5	O75197-1.2	Q292M	Neutral	0.054
LRP5	O75197-1.2	Q292N	Neutral	0.128
LRP5	O75197-1.2	Q292P	Neutral	0.212
LRP5	O75197-1.2	Q292R	Neutral	0.032
LRP5	O75197-1.2	Q292S	Neutral	0.145
LRP5	O75197-1.2	Q292T	Neutral	0.29
LRP5	O75197-1.2	Q292V	Neutral	0.349
LRP5	O75197-1.2	Q292W	Neutral	0.167
LRP5	O75197-1.2	Q292Y	Neutral	0.177
LRP5	O75197-1.2	P293A	Neutral	0.082
LRP5	O75197-1.2	P293C	Neutral	0.492
LRP5	O75197-1.2	P293D	Neutral	0.034
LRP5	O75197-1.2	P293E	Neutral	0.037
LRP5	O75197-1.2	P293F	Pathogenic	0.573
LRP5	O75197-1.2	P293G	Neutral	0.166
LRP5	O75197-1.2	P293H	Neutral	0.187
LRP5	O75197-1.2	P293I	Neutral	0.307
LRP5	O75197-1.2	P293K	Neutral	0.026
LRP5	O75197-1.2	P293L	Neutral	0.327
LRP5	O75197-1.2	P293M	Neutral	0.195
LRP5	O75197-1.2	P293N	Neutral	0.11
LRP5	O75197-1.2	P293Q	Neutral	0.052
LRP5	O75197-1.2	P293R	Neutral	0.073
LRP5	O75197-1.2	P293S	Neutral	0.062
LRP5	O75197-1.2	P293T	Neutral	0.081
LRP5	O75197-1.2	P293V	Neutral	0.202
LRP5	O75197-1.2	P293W	Neutral	0.459
LRP5	O75197-1.2	P293Y	Neutral	0.478
LRP5	O75197-1.2	F294A	Neutral	0.0
LRP5	O75197-1.2	F294C	Neutral	0.0
LRP5	O75197-1.2	F294D	Neutral	0.0
LRP5	O75197-1.2	F294E	Neutral	0.0
LRP5	O75197-1.2	F294G	Neutral	0.0
LRP5	O75197-1.2	F294H	Neutral	0.0
LRP5	O75197-1.2	F294I	Neutral	0.0
LRP5	O75197-1.2	F294K	Neutral	0.0
LRP5	O75197-1.2	F294L	Neutral	0.0
LRP5	O75197-1.2	F294M	Neutral	0.0
LRP5	O75197-1.2	F294N	Neutral	0.0
LRP5	O75197-1.2	F294P	Neutral	0.0
LRP5	O75197-1.2	F294Q	Neutral	0.0
LRP5	O75197-1.2	F294R	Neutral	0.0
LRP5	O75197-1.2	F294S	Neutral	0.0
LRP5	O75197-1.2	F294T	Neutral	0.0
LRP5	O75197-1.2	F294V	Neutral	0.0
LRP5	O75197-1.2	F294W	Neutral	0.0
LRP5	O75197-1.2	F294Y	Neutral	0.0
LRP5	O75197-1.2	F295A	Neutral	0.0
LRP5	O75197-1.2	F295C	Neutral	0.0
LRP5	O75197-1.2	F295D	Neutral	0.0
LRP5	O75197-1.2	F295E	Neutral	0.0
LRP5	O75197-1.2	F295G	Neutral	0.0
LRP5	O75197-1.2	F295H	Neutral	0.0
LRP5	O75197-1.2	F295I	Neutral	0.0
LRP5	O75197-1.2	F295K	Neutral	0.0
LRP5	O75197-1.2	F295L	Neutral	0.0
LRP5	O75197-1.2	F295M	Neutral	0.0
LRP5	O75197-1.2	F295N	Neutral	0.0
LRP5	O75197-1.2	F295P	Neutral	0.001
LRP5	O75197-1.2	F295Q	Neutral	0.0
LRP5	O75197-1.2	F295R	Neutral	0.0
LRP5	O75197-1.2	F295S	Neutral	0.0
LRP5	O75197-1.2	F295T	Neutral	0.0
LRP5	O75197-1.2	F295V	Neutral	0.0
LRP5	O75197-1.2	F295W	Neutral	0.0
LRP5	O75197-1.2	F295Y	Neutral	0.0
LRP5	O75197-1.2	H296A	Neutral	0.0
LRP5	O75197-1.2	H296C	Neutral	0.001
LRP5	O75197-1.2	H296D	Neutral	0.0
LRP5	O75197-1.2	H296E	Neutral	0.0
LRP5	O75197-1.2	H296F	Neutral	0.0
LRP5	O75197-1.2	H296G	Neutral	0.0
LRP5	O75197-1.2	H296I	Neutral	0.0
LRP5	O75197-1.2	H296K	Neutral	0.0
LRP5	O75197-1.2	H296L	Neutral	0.0
LRP5	O75197-1.2	H296M	Neutral	0.0
LRP5	O75197-1.2	H296N	Neutral	0.0
LRP5	O75197-1.2	H296P	Neutral	0.0
LRP5	O75197-1.2	H296Q	Neutral	0.0
LRP5	O75197-1.2	H296R	Neutral	0.0
LRP5	O75197-1.2	H296S	Neutral	0.0
LRP5	O75197-1.2	H296T	Neutral	0.0
LRP5	O75197-1.2	H296V	Neutral	0.001
LRP5	O75197-1.2	H296W	Neutral	0.0
LRP5	O75197-1.2	H296Y	Neutral	0.0
LRP5	O75197-1.2	T297A	Neutral	0.0
LRP5	O75197-1.2	T297C	Neutral	0.001
LRP5	O75197-1.2	T297D	Neutral	0.0
LRP5	O75197-1.2	T297E	Neutral	0.001
LRP5	O75197-1.2	T297F	Neutral	0.001
LRP5	O75197-1.2	T297G	Neutral	0.003
LRP5	O75197-1.2	T297H	Neutral	0.003
LRP5	O75197-1.2	T297I	Neutral	0.0
LRP5	O75197-1.2	T297K	Neutral	0.0
LRP5	O75197-1.2	T297L	Neutral	0.0
LRP5	O75197-1.2	T297M	Neutral	0.0
LRP5	O75197-1.2	T297N	Neutral	0.0
LRP5	O75197-1.2	T297P	Neutral	0.001
LRP5	O75197-1.2	T297Q	Neutral	0.001
LRP5	O75197-1.2	T297R	Neutral	0.0
LRP5	O75197-1.2	T297S	Neutral	0.0
LRP5	O75197-1.2	T297V	Neutral	0.0
LRP5	O75197-1.2	T297W	Neutral	0.001
LRP5	O75197-1.2	T297Y	Neutral	0.002
LRP5	O75197-1.2	R298A	Neutral	0.0
LRP5	O75197-1.2	R298C	Neutral	0.001
LRP5	O75197-1.2	R298D	Neutral	0.001
LRP5	O75197-1.2	R298E	Neutral	0.0
LRP5	O75197-1.2	R298F	Neutral	0.0
LRP5	O75197-1.2	R298G	Neutral	0.0
LRP5	O75197-1.2	R298H	Neutral	0.0
LRP5	O75197-1.2	R298I	Neutral	0.0
LRP5	O75197-1.2	R298K	Neutral	0.0
LRP5	O75197-1.2	R298L	Neutral	0.0
LRP5	O75197-1.2	R298M	Neutral	0.0
LRP5	O75197-1.2	R298N	Neutral	0.0
LRP5	O75197-1.2	R298P	Neutral	0.0
LRP5	O75197-1.2	R298Q	Neutral	0.0
LRP5	O75197-1.2	R298S	Neutral	0.0
LRP5	O75197-1.2	R298T	Neutral	0.0
LRP5	O75197-1.2	R298V	Neutral	0.001
LRP5	O75197-1.2	R298W	Neutral	0.0
LRP5	O75197-1.2	R298Y	Neutral	0.0
LRP5	O75197-1.2	C299A	Pathogenic	0.988
LRP5	O75197-1.2	C299D	Pathogenic	0.999
LRP5	O75197-1.2	C299E	Pathogenic	1.0
LRP5	O75197-1.2	C299F	Pathogenic	0.998
LRP5	O75197-1.2	C299G	Pathogenic	0.999
LRP5	O75197-1.2	C299H	Pathogenic	0.999
LRP5	O75197-1.2	C299I	Pathogenic	0.995
LRP5	O75197-1.2	C299K	Pathogenic	0.999
LRP5	O75197-1.2	C299L	Pathogenic	0.996
LRP5	O75197-1.2	C299M	Pathogenic	0.997
LRP5	O75197-1.2	C299N	Pathogenic	0.999
LRP5	O75197-1.2	C299P	Pathogenic	1.0
LRP5	O75197-1.2	C299Q	Pathogenic	0.999
LRP5	O75197-1.2	C299R	Pathogenic	0.998
LRP5	O75197-1.2	C299S	Pathogenic	0.994
LRP5	O75197-1.2	C299T	Pathogenic	0.996
LRP5	O75197-1.2	C299V	Pathogenic	0.997
LRP5	O75197-1.2	C299W	Pathogenic	0.997
LRP5	O75197-1.2	C299Y	Pathogenic	0.999
LRP5	O75197-1.2	E300A	Neutral	0.0
LRP5	O75197-1.2	E300C	Neutral	0.001
LRP5	O75197-1.2	E300D	Neutral	0.0
LRP5	O75197-1.2	E300F	Neutral	0.0
LRP5	O75197-1.2	E300G	Neutral	0.0
LRP5	O75197-1.2	E300H	Neutral	0.0
LRP5	O75197-1.2	E300I	Neutral	0.0
LRP5	O75197-1.2	E300K	Neutral	0.0
LRP5	O75197-1.2	E300L	Neutral	0.0
LRP5	O75197-1.2	E300M	Neutral	0.0
LRP5	O75197-1.2	E300N	Neutral	0.0
LRP5	O75197-1.2	E300P	Neutral	0.0
LRP5	O75197-1.2	E300Q	Neutral	0.0
LRP5	O75197-1.2	E300R	Neutral	0.0
LRP5	O75197-1.2	E300S	Neutral	0.0
LRP5	O75197-1.2	E300T	Neutral	0.0
LRP5	O75197-1.2	E300V	Neutral	0.0
LRP5	O75197-1.2	E300W	Neutral	0.0
LRP5	O75197-1.2	E300Y	Neutral	0.0
LRP5	O75197-1.2	E301A	Neutral	0.0
LRP5	O75197-1.2	E301C	Neutral	0.0
LRP5	O75197-1.2	E301D	Neutral	0.0
LRP5	O75197-1.2	E301F	Neutral	0.0
LRP5	O75197-1.2	E301G	Neutral	0.0
LRP5	O75197-1.2	E301H	Neutral	0.0
LRP5	O75197-1.2	E301I	Neutral	0.0
LRP5	O75197-1.2	E301K	Neutral	0.0
LRP5	O75197-1.2	E301L	Neutral	0.0
LRP5	O75197-1.2	E301M	Neutral	0.0
LRP5	O75197-1.2	E301N	Neutral	0.0
LRP5	O75197-1.2	E301P	Neutral	0.0
LRP5	O75197-1.2	E301Q	Neutral	0.0
LRP5	O75197-1.2	E301R	Neutral	0.0
LRP5	O75197-1.2	E301S	Neutral	0.0
LRP5	O75197-1.2	E301T	Neutral	0.0
LRP5	O75197-1.2	E301V	Neutral	0.0
LRP5	O75197-1.2	E301W	Neutral	0.0
LRP5	O75197-1.2	E301Y	Neutral	0.0
LRP5	O75197-1.2	D302A	Neutral	0.0
LRP5	O75197-1.2	D302C	Neutral	0.001
LRP5	O75197-1.2	D302E	Neutral	0.0
LRP5	O75197-1.2	D302F	Neutral	0.0
LRP5	O75197-1.2	D302G	Neutral	0.0
LRP5	O75197-1.2	D302H	Neutral	0.0
LRP5	O75197-1.2	D302I	Neutral	0.0
LRP5	O75197-1.2	D302K	Neutral	0.0
LRP5	O75197-1.2	D302L	Neutral	0.001
LRP5	O75197-1.2	D302M	Neutral	0.001
LRP5	O75197-1.2	D302N	Neutral	0.0
LRP5	O75197-1.2	D302P	Neutral	0.0
LRP5	O75197-1.2	D302Q	Neutral	0.0
LRP5	O75197-1.2	D302R	Neutral	0.001
LRP5	O75197-1.2	D302S	Neutral	0.0
LRP5	O75197-1.2	D302T	Neutral	0.0
LRP5	O75197-1.2	D302V	Neutral	0.001
LRP5	O75197-1.2	D302W	Neutral	0.001
LRP5	O75197-1.2	D302Y	Neutral	0.001
LRP5	O75197-1.2	N303A	Neutral	0.419
LRP5	O75197-1.2	N303C	Pathogenic	0.553
LRP5	O75197-1.2	N303D	Neutral	0.049
LRP5	O75197-1.2	N303E	Neutral	0.149
LRP5	O75197-1.2	N303F	Neutral	0.365
LRP5	O75197-1.2	N303G	Neutral	0.091
LRP5	O75197-1.2	N303H	Neutral	0.029
LRP5	O75197-1.2	N303I	Neutral	0.366
LRP5	O75197-1.2	N303K	Neutral	0.109
LRP5	O75197-1.2	N303L	Neutral	0.387
LRP5	O75197-1.2	N303M	Neutral	0.24
LRP5	O75197-1.2	N303P	Neutral	0.341
LRP5	O75197-1.2	N303Q	Neutral	0.113
LRP5	O75197-1.2	N303R	Neutral	0.106
LRP5	O75197-1.2	N303S	Neutral	0.034
LRP5	O75197-1.2	N303T	Neutral	0.078
LRP5	O75197-1.2	N303V	Pathogenic	0.501
LRP5	O75197-1.2	N303W	Pathogenic	0.525
LRP5	O75197-1.2	N303Y	Neutral	0.282
LRP5	O75197-1.2	G304A	Neutral	0.028
LRP5	O75197-1.2	G304C	Neutral	0.304
LRP5	O75197-1.2	G304D	Neutral	0.054
LRP5	O75197-1.2	G304E	Neutral	0.159
LRP5	O75197-1.2	G304F	Neutral	0.164
LRP5	O75197-1.2	G304H	Neutral	0.226
LRP5	O75197-1.2	G304I	Neutral	0.375
LRP5	O75197-1.2	G304K	Neutral	0.117
LRP5	O75197-1.2	G304L	Neutral	0.397
LRP5	O75197-1.2	G304M	Neutral	0.248
LRP5	O75197-1.2	G304N	Neutral	0.021
LRP5	O75197-1.2	G304P	Neutral	0.153
LRP5	O75197-1.2	G304Q	Neutral	0.214
LRP5	O75197-1.2	G304R	Neutral	0.113
LRP5	O75197-1.2	G304S	Neutral	0.036
LRP5	O75197-1.2	G304T	Neutral	0.214
LRP5	O75197-1.2	G304V	Neutral	0.256
LRP5	O75197-1.2	G304W	Neutral	0.039
LRP5	O75197-1.2	G304Y	Neutral	0.29
LRP5	O75197-1.2	G305A	Neutral	0.01
LRP5	O75197-1.2	G305C	Neutral	0.135
LRP5	O75197-1.2	G305D	Neutral	0.02
LRP5	O75197-1.2	G305E	Neutral	0.063
LRP5	O75197-1.2	G305F	Neutral	0.065
LRP5	O75197-1.2	G305H	Neutral	0.094
LRP5	O75197-1.2	G305I	Neutral	0.176
LRP5	O75197-1.2	G305K	Neutral	0.045
LRP5	O75197-1.2	G305L	Neutral	0.19
LRP5	O75197-1.2	G305M	Neutral	0.105
LRP5	O75197-1.2	G305N	Neutral	0.008
LRP5	O75197-1.2	G305P	Neutral	0.06
LRP5	O75197-1.2	G305Q	Neutral	0.088
LRP5	O75197-1.2	G305R	Neutral	0.043
LRP5	O75197-1.2	G305S	Neutral	0.013
LRP5	O75197-1.2	G305T	Neutral	0.088
LRP5	O75197-1.2	G305V	Neutral	0.109
LRP5	O75197-1.2	G305W	Neutral	0.014
LRP5	O75197-1.2	G305Y	Neutral	0.127
LRP5	O75197-1.2	C306A	Pathogenic	0.984
LRP5	O75197-1.2	C306D	Pathogenic	0.999
LRP5	O75197-1.2	C306E	Pathogenic	1.0
LRP5	O75197-1.2	C306F	Pathogenic	0.998
LRP5	O75197-1.2	C306G	Pathogenic	0.999
LRP5	O75197-1.2	C306H	Pathogenic	0.999
LRP5	O75197-1.2	C306I	Pathogenic	0.994
LRP5	O75197-1.2	C306K	Pathogenic	0.998
LRP5	O75197-1.2	C306L	Pathogenic	0.994
LRP5	O75197-1.2	C306M	Pathogenic	0.996
LRP5	O75197-1.2	C306N	Pathogenic	0.999
LRP5	O75197-1.2	C306P	Pathogenic	1.0
LRP5	O75197-1.2	C306Q	Pathogenic	0.999
LRP5	O75197-1.2	C306R	Pathogenic	0.998
LRP5	O75197-1.2	C306S	Pathogenic	0.993
LRP5	O75197-1.2	C306T	Pathogenic	0.995
LRP5	O75197-1.2	C306V	Pathogenic	0.996
LRP5	O75197-1.2	C306W	Pathogenic	0.997
LRP5	O75197-1.2	C306Y	Pathogenic	0.999
LRP5	O75197-1.2	S307A	Neutral	0.018
LRP5	O75197-1.2	S307C	Neutral	0.083
LRP5	O75197-1.2	S307D	Neutral	0.037
LRP5	O75197-1.2	S307E	Neutral	0.04
LRP5	O75197-1.2	S307F	Neutral	0.11
LRP5	O75197-1.2	S307G	Neutral	0.065
LRP5	O75197-1.2	S307H	Neutral	0.155
LRP5	O75197-1.2	S307I	Neutral	0.11
LRP5	O75197-1.2	S307K	Neutral	0.028
LRP5	O75197-1.2	S307L	Neutral	0.12
LRP5	O75197-1.2	S307M	Neutral	0.064
LRP5	O75197-1.2	S307N	Neutral	0.014
LRP5	O75197-1.2	S307P	Neutral	0.102
LRP5	O75197-1.2	S307Q	Neutral	0.057
LRP5	O75197-1.2	S307R	Neutral	0.079
LRP5	O75197-1.2	S307T	Neutral	0.018
LRP5	O75197-1.2	S307V	Neutral	0.178
LRP5	O75197-1.2	S307W	Neutral	0.192
LRP5	O75197-1.2	S307Y	Neutral	0.204
LRP5	O75197-1.2	H308A	Pathogenic	0.649
LRP5	O75197-1.2	H308C	Pathogenic	0.76
LRP5	O75197-1.2	H308D	Neutral	0.248
LRP5	O75197-1.2	H308E	Neutral	0.111
LRP5	O75197-1.2	H308F	Neutral	0.146
LRP5	O75197-1.2	H308G	Pathogenic	0.651
LRP5	O75197-1.2	H308I	Pathogenic	0.613
LRP5	O75197-1.2	H308K	Neutral	0.216
LRP5	O75197-1.2	H308L	Pathogenic	0.635
LRP5	O75197-1.2	H308M	Neutral	0.465
LRP5	O75197-1.2	H308N	Neutral	0.04
LRP5	O75197-1.2	H308P	Pathogenic	0.57
LRP5	O75197-1.2	H308Q	Neutral	0.155
LRP5	O75197-1.2	H308R	Neutral	0.08
LRP5	O75197-1.2	H308S	Neutral	0.381
LRP5	O75197-1.2	H308T	Pathogenic	0.668
LRP5	O75197-1.2	H308V	Pathogenic	0.726
LRP5	O75197-1.2	H308W	Neutral	0.247
LRP5	O75197-1.2	H308Y	Neutral	0.012
LRP5	O75197-1.2	L309A	Neutral	0.037
LRP5	O75197-1.2	L309C	Neutral	0.067
LRP5	O75197-1.2	L309D	Neutral	0.298
LRP5	O75197-1.2	L309E	Neutral	0.139
LRP5	O75197-1.2	L309F	Neutral	0.041
LRP5	O75197-1.2	L309G	Neutral	0.441
LRP5	O75197-1.2	L309H	Neutral	0.246
LRP5	O75197-1.2	L309I	Neutral	0.005
LRP5	O75197-1.2	L309K	Neutral	0.038
LRP5	O75197-1.2	L309M	Neutral	0.003
LRP5	O75197-1.2	L309N	Neutral	0.141
LRP5	O75197-1.2	L309P	Neutral	0.346
LRP5	O75197-1.2	L309Q	Neutral	0.072
LRP5	O75197-1.2	L309R	Neutral	0.036
LRP5	O75197-1.2	L309S	Neutral	0.079
LRP5	O75197-1.2	L309T	Neutral	0.037
LRP5	O75197-1.2	L309V	Neutral	0.01
LRP5	O75197-1.2	L309W	Neutral	0.202
LRP5	O75197-1.2	L309Y	Neutral	0.068
LRP5	O75197-1.2	C310A	Pathogenic	0.987
LRP5	O75197-1.2	C310D	Pathogenic	0.999
LRP5	O75197-1.2	C310E	Pathogenic	1.0
LRP5	O75197-1.2	C310F	Pathogenic	0.998
LRP5	O75197-1.2	C310G	Pathogenic	0.999
LRP5	O75197-1.2	C310H	Pathogenic	0.999
LRP5	O75197-1.2	C310I	Pathogenic	0.995
LRP5	O75197-1.2	C310K	Pathogenic	0.998
LRP5	O75197-1.2	C310L	Pathogenic	0.995
LRP5	O75197-1.2	C310M	Pathogenic	0.997
LRP5	O75197-1.2	C310N	Pathogenic	0.999
LRP5	O75197-1.2	C310P	Pathogenic	1.0
LRP5	O75197-1.2	C310Q	Pathogenic	0.999
LRP5	O75197-1.2	C310R	Pathogenic	0.998
LRP5	O75197-1.2	C310S	Pathogenic	0.994
LRP5	O75197-1.2	C310T	Pathogenic	0.996
LRP5	O75197-1.2	C310V	Pathogenic	0.997
LRP5	O75197-1.2	C310W	Pathogenic	0.997
LRP5	O75197-1.2	C310Y	Pathogenic	0.999
LRP5	O75197-1.2	L311A	Neutral	0.039
LRP5	O75197-1.2	L311C	Neutral	0.071
LRP5	O75197-1.2	L311D	Neutral	0.312
LRP5	O75197-1.2	L311E	Neutral	0.147
LRP5	O75197-1.2	L311F	Neutral	0.044
LRP5	O75197-1.2	L311G	Neutral	0.458
LRP5	O75197-1.2	L311H	Neutral	0.259
LRP5	O75197-1.2	L311I	Neutral	0.005
LRP5	O75197-1.2	L311K	Neutral	0.04
LRP5	O75197-1.2	L311M	Neutral	0.004
LRP5	O75197-1.2	L311N	Neutral	0.149
LRP5	O75197-1.2	L311P	Neutral	0.361
LRP5	O75197-1.2	L311Q	Neutral	0.077
LRP5	O75197-1.2	L311R	Neutral	0.039
LRP5	O75197-1.2	L311S	Neutral	0.084
LRP5	O75197-1.2	L311T	Neutral	0.039
LRP5	O75197-1.2	L311V	Neutral	0.01
LRP5	O75197-1.2	L311W	Neutral	0.213
LRP5	O75197-1.2	L311Y	Neutral	0.072
LRP5	O75197-1.2	L312A	Neutral	0.002
LRP5	O75197-1.2	L312C	Neutral	0.003
LRP5	O75197-1.2	L312D	Neutral	0.019
LRP5	O75197-1.2	L312E	Neutral	0.007
LRP5	O75197-1.2	L312F	Neutral	0.002
LRP5	O75197-1.2	L312G	Neutral	0.034
LRP5	O75197-1.2	L312H	Neutral	0.015
LRP5	O75197-1.2	L312I	Neutral	0.0
LRP5	O75197-1.2	L312K	Neutral	0.002
LRP5	O75197-1.2	L312M	Neutral	0.0
LRP5	O75197-1.2	L312N	Neutral	0.007
LRP5	O75197-1.2	L312P	Neutral	0.023
LRP5	O75197-1.2	L312Q	Neutral	0.004
LRP5	O75197-1.2	L312R	Neutral	0.002
LRP5	O75197-1.2	L312S	Neutral	0.004
LRP5	O75197-1.2	L312T	Neutral	0.002
LRP5	O75197-1.2	L312V	Neutral	0.0
LRP5	O75197-1.2	L312W	Neutral	0.011
LRP5	O75197-1.2	L312Y	Neutral	0.003
LRP5	O75197-1.2	S313A	Neutral	0.006
LRP5	O75197-1.2	S313C	Neutral	0.029
LRP5	O75197-1.2	S313D	Neutral	0.012
LRP5	O75197-1.2	S313E	Neutral	0.014
LRP5	O75197-1.2	S313F	Neutral	0.039
LRP5	O75197-1.2	S313G	Neutral	0.023
LRP5	O75197-1.2	S313H	Neutral	0.057
LRP5	O75197-1.2	S313I	Neutral	0.039
LRP5	O75197-1.2	S313K	Neutral	0.009
LRP5	O75197-1.2	S313L	Neutral	0.043
LRP5	O75197-1.2	S313M	Neutral	0.022
LRP5	O75197-1.2	S313N	Neutral	0.005
LRP5	O75197-1.2	S313P	Neutral	0.036
LRP5	O75197-1.2	S313Q	Neutral	0.019
LRP5	O75197-1.2	S313R	Neutral	0.027
LRP5	O75197-1.2	S313T	Neutral	0.006
LRP5	O75197-1.2	S313V	Neutral	0.066
LRP5	O75197-1.2	S313W	Neutral	0.073
LRP5	O75197-1.2	S313Y	Neutral	0.078
LRP5	O75197-1.2	P314A	Neutral	0.03
LRP5	O75197-1.2	P314C	Neutral	0.251
LRP5	O75197-1.2	P314D	Neutral	0.012
LRP5	O75197-1.2	P314E	Neutral	0.013
LRP5	O75197-1.2	P314F	Neutral	0.317
LRP5	O75197-1.2	P314G	Neutral	0.065
LRP5	O75197-1.2	P314H	Neutral	0.074
LRP5	O75197-1.2	P314I	Neutral	0.133
LRP5	O75197-1.2	P314K	Neutral	0.009
LRP5	O75197-1.2	P314L	Neutral	0.144
LRP5	O75197-1.2	P314M	Neutral	0.078
LRP5	O75197-1.2	P314N	Neutral	0.041
LRP5	O75197-1.2	P314Q	Neutral	0.019
LRP5	O75197-1.2	P314R	Neutral	0.027
LRP5	O75197-1.2	P314S	Neutral	0.022
LRP5	O75197-1.2	P314T	Neutral	0.03
LRP5	O75197-1.2	P314V	Neutral	0.081
LRP5	O75197-1.2	P314W	Neutral	0.227
LRP5	O75197-1.2	P314Y	Neutral	0.241
LRP5	O75197-1.2	S315A	Neutral	0.0
LRP5	O75197-1.2	S315C	Neutral	0.0
LRP5	O75197-1.2	S315D	Neutral	0.0
LRP5	O75197-1.2	S315E	Neutral	0.0
LRP5	O75197-1.2	S315F	Neutral	0.0
LRP5	O75197-1.2	S315G	Neutral	0.0
LRP5	O75197-1.2	S315H	Neutral	0.0
LRP5	O75197-1.2	S315I	Neutral	0.0
LRP5	O75197-1.2	S315K	Neutral	0.0
LRP5	O75197-1.2	S315L	Neutral	0.0
LRP5	O75197-1.2	S315M	Neutral	0.0
LRP5	O75197-1.2	S315N	Neutral	0.0
LRP5	O75197-1.2	S315P	Neutral	0.0
LRP5	O75197-1.2	S315Q	Neutral	0.0
LRP5	O75197-1.2	S315R	Neutral	0.0
LRP5	O75197-1.2	S315T	Neutral	0.0
LRP5	O75197-1.2	S315V	Neutral	0.0
LRP5	O75197-1.2	S315W	Neutral	0.0
LRP5	O75197-1.2	S315Y	Neutral	0.0
LRP5	O75197-1.2	E316A	Neutral	0.0
LRP5	O75197-1.2	E316C	Neutral	0.001
LRP5	O75197-1.2	E316D	Neutral	0.0
LRP5	O75197-1.2	E316F	Neutral	0.0
LRP5	O75197-1.2	E316G	Neutral	0.0
LRP5	O75197-1.2	E316H	Neutral	0.0
LRP5	O75197-1.2	E316I	Neutral	0.0
LRP5	O75197-1.2	E316K	Neutral	0.0
LRP5	O75197-1.2	E316L	Neutral	0.0
LRP5	O75197-1.2	E316M	Neutral	0.0
LRP5	O75197-1.2	E316N	Neutral	0.0
LRP5	O75197-1.2	E316P	Neutral	0.0
LRP5	O75197-1.2	E316Q	Neutral	0.0
LRP5	O75197-1.2	E316R	Neutral	0.0
LRP5	O75197-1.2	E316S	Neutral	0.0
LRP5	O75197-1.2	E316T	Neutral	0.0
LRP5	O75197-1.2	E316V	Neutral	0.0
LRP5	O75197-1.2	E316W	Neutral	0.0
LRP5	O75197-1.2	E316Y	Neutral	0.0
LRP5	O75197-1.2	P317A	Neutral	0.057
LRP5	O75197-1.2	P317C	Neutral	0.397
LRP5	O75197-1.2	P317D	Neutral	0.023
LRP5	O75197-1.2	P317E	Neutral	0.025
LRP5	O75197-1.2	P317F	Neutral	0.477
LRP5	O75197-1.2	P317G	Neutral	0.119
LRP5	O75197-1.2	P317H	Neutral	0.135
LRP5	O75197-1.2	P317I	Neutral	0.231
LRP5	O75197-1.2	P317K	Neutral	0.018
LRP5	O75197-1.2	P317L	Neutral	0.248
LRP5	O75197-1.2	P317M	Neutral	0.142
LRP5	O75197-1.2	P317N	Neutral	0.077
LRP5	O75197-1.2	P317Q	Neutral	0.036
LRP5	O75197-1.2	P317R	Neutral	0.051
LRP5	O75197-1.2	P317S	Neutral	0.043
LRP5	O75197-1.2	P317T	Neutral	0.056
LRP5	O75197-1.2	P317V	Neutral	0.147
LRP5	O75197-1.2	P317W	Neutral	0.366
LRP5	O75197-1.2	P317Y	Neutral	0.384
LRP5	O75197-1.2	F318A	Neutral	0.005
LRP5	O75197-1.2	F318C	Neutral	0.008
LRP5	O75197-1.2	F318D	Neutral	0.005
LRP5	O75197-1.2	F318E	Neutral	0.006
LRP5	O75197-1.2	F318G	Neutral	0.01
LRP5	O75197-1.2	F318H	Neutral	0.001
LRP5	O75197-1.2	F318I	Neutral	0.002
LRP5	O75197-1.2	F318K	Neutral	0.005
LRP5	O75197-1.2	F318L	Neutral	0.002
LRP5	O75197-1.2	F318M	Neutral	0.001
LRP5	O75197-1.2	F318N	Neutral	0.006
LRP5	O75197-1.2	F318P	Neutral	0.059
LRP5	O75197-1.2	F318Q	Neutral	0.009
LRP5	O75197-1.2	F318R	Neutral	0.005
LRP5	O75197-1.2	F318S	Neutral	0.003
LRP5	O75197-1.2	F318T	Neutral	0.004
LRP5	O75197-1.2	F318V	Neutral	0.004
LRP5	O75197-1.2	F318W	Neutral	0.0
LRP5	O75197-1.2	F318Y	Neutral	0.0
LRP5	O75197-1.2	Y319A	Neutral	0.177
LRP5	O75197-1.2	Y319C	Neutral	0.28
LRP5	O75197-1.2	Y319D	Neutral	0.206
LRP5	O75197-1.2	Y319E	Neutral	0.09
LRP5	O75197-1.2	Y319F	Neutral	0.001
LRP5	O75197-1.2	Y319G	Neutral	0.325
LRP5	O75197-1.2	Y319H	Neutral	0.002
LRP5	O75197-1.2	Y319I	Neutral	0.061
LRP5	O75197-1.2	Y319K	Neutral	0.07
LRP5	O75197-1.2	Y319L	Neutral	0.067
LRP5	O75197-1.2	Y319M	Neutral	0.098
LRP5	O75197-1.2	Y319N	Neutral	0.091
LRP5	O75197-1.2	Y319P	Neutral	0.495
LRP5	O75197-1.2	Y319Q	Neutral	0.045
LRP5	O75197-1.2	Y319R	Neutral	0.069
LRP5	O75197-1.2	Y319S	Neutral	0.138
LRP5	O75197-1.2	Y319T	Neutral	0.176
LRP5	O75197-1.2	Y319V	Neutral	0.097
LRP5	O75197-1.2	Y319W	Neutral	0.002
LRP5	O75197-1.2	T320A	Neutral	0.0
LRP5	O75197-1.2	T320C	Neutral	0.0
LRP5	O75197-1.2	T320D	Neutral	0.0
LRP5	O75197-1.2	T320E	Neutral	0.0
LRP5	O75197-1.2	T320F	Neutral	0.0
LRP5	O75197-1.2	T320G	Neutral	0.0
LRP5	O75197-1.2	T320H	Neutral	0.0
LRP5	O75197-1.2	T320I	Neutral	0.0
LRP5	O75197-1.2	T320K	Neutral	0.0
LRP5	O75197-1.2	T320L	Neutral	0.0
LRP5	O75197-1.2	T320M	Neutral	0.0
LRP5	O75197-1.2	T320N	Neutral	0.0
LRP5	O75197-1.2	T320P	Neutral	0.0
LRP5	O75197-1.2	T320Q	Neutral	0.0
LRP5	O75197-1.2	T320R	Neutral	0.0
LRP5	O75197-1.2	T320S	Neutral	0.0
LRP5	O75197-1.2	T320V	Neutral	0.0
LRP5	O75197-1.2	T320W	Neutral	0.0
LRP5	O75197-1.2	T320Y	Neutral	0.0
LRP5	O75197-1.2	C321A	Pathogenic	0.984
LRP5	O75197-1.2	C321D	Pathogenic	0.999
LRP5	O75197-1.2	C321E	Pathogenic	1.0
LRP5	O75197-1.2	C321F	Pathogenic	0.998
LRP5	O75197-1.2	C321G	Pathogenic	0.999
LRP5	O75197-1.2	C321H	Pathogenic	0.999
LRP5	O75197-1.2	C321I	Pathogenic	0.994
LRP5	O75197-1.2	C321K	Pathogenic	0.998
LRP5	O75197-1.2	C321L	Pathogenic	0.994
LRP5	O75197-1.2	C321M	Pathogenic	0.996
LRP5	O75197-1.2	C321N	Pathogenic	0.999
LRP5	O75197-1.2	C321P	Pathogenic	1.0
LRP5	O75197-1.2	C321Q	Pathogenic	0.999
LRP5	O75197-1.2	C321R	Pathogenic	0.998
LRP5	O75197-1.2	C321S	Pathogenic	0.993
LRP5	O75197-1.2	C321T	Pathogenic	0.994
LRP5	O75197-1.2	C321V	Pathogenic	0.996
LRP5	O75197-1.2	C321W	Pathogenic	0.997
LRP5	O75197-1.2	C321Y	Pathogenic	0.999
LRP5	O75197-1.2	A322C	Neutral	0.028
LRP5	O75197-1.2	A322D	Neutral	0.156
LRP5	O75197-1.2	A322E	Neutral	0.062
LRP5	O75197-1.2	A322F	Neutral	0.108
LRP5	O75197-1.2	A322G	Neutral	0.039
LRP5	O75197-1.2	A322H	Neutral	0.285
LRP5	O75197-1.2	A322I	Neutral	0.038
LRP5	O75197-1.2	A322K	Neutral	0.045
LRP5	O75197-1.2	A322L	Neutral	0.042
LRP5	O75197-1.2	A322M	Neutral	0.062
LRP5	O75197-1.2	A322N	Neutral	0.176
LRP5	O75197-1.2	A322P	Neutral	0.1
LRP5	O75197-1.2	A322Q	Neutral	0.088
LRP5	O75197-1.2	A322R	Neutral	0.043
LRP5	O75197-1.2	A322S	Neutral	0.013
LRP5	O75197-1.2	A322T	Neutral	0.048
LRP5	O75197-1.2	A322V	Neutral	0.022
LRP5	O75197-1.2	A322W	Neutral	0.188
LRP5	O75197-1.2	A322Y	Neutral	0.2
LRP5	O75197-1.2	C323A	Pathogenic	0.983
LRP5	O75197-1.2	C323D	Pathogenic	0.998
LRP5	O75197-1.2	C323E	Pathogenic	1.0
LRP5	O75197-1.2	C323F	Pathogenic	0.998
LRP5	O75197-1.2	C323G	Pathogenic	0.999
LRP5	O75197-1.2	C323H	Pathogenic	0.999
LRP5	O75197-1.2	C323I	Pathogenic	0.993
LRP5	O75197-1.2	C323K	Pathogenic	0.998
LRP5	O75197-1.2	C323L	Pathogenic	0.994
LRP5	O75197-1.2	C323M	Pathogenic	0.996
LRP5	O75197-1.2	C323N	Pathogenic	0.999
LRP5	O75197-1.2	C323P	Pathogenic	1.0
LRP5	O75197-1.2	C323Q	Pathogenic	0.999
LRP5	O75197-1.2	C323R	Pathogenic	0.998
LRP5	O75197-1.2	C323S	Pathogenic	0.992
LRP5	O75197-1.2	C323T	Pathogenic	0.994
LRP5	O75197-1.2	C323V	Pathogenic	0.996
LRP5	O75197-1.2	C323W	Pathogenic	0.996
LRP5	O75197-1.2	C323Y	Pathogenic	0.999
LRP5	O75197-1.2	P324A	Neutral	0.135
LRP5	O75197-1.2	P324C	Pathogenic	0.629
LRP5	O75197-1.2	P324D	Neutral	0.058
LRP5	O75197-1.2	P324E	Neutral	0.063
LRP5	O75197-1.2	P324F	Pathogenic	0.701
LRP5	O75197-1.2	P324G	Neutral	0.259
LRP5	O75197-1.2	P324H	Neutral	0.287
LRP5	O75197-1.2	P324I	Neutral	0.437
LRP5	O75197-1.2	P324K	Neutral	0.045
LRP5	O75197-1.2	P324L	Neutral	0.46
LRP5	O75197-1.2	P324M	Neutral	0.298
LRP5	O75197-1.2	P324N	Neutral	0.178
LRP5	O75197-1.2	P324Q	Neutral	0.089
LRP5	O75197-1.2	P324R	Neutral	0.122
LRP5	O75197-1.2	P324S	Neutral	0.104
LRP5	O75197-1.2	P324T	Neutral	0.133
LRP5	O75197-1.2	P324V	Neutral	0.308
LRP5	O75197-1.2	P324W	Pathogenic	0.598
LRP5	O75197-1.2	P324Y	Pathogenic	0.616
LRP5	O75197-1.2	T325A	Neutral	0.067
LRP5	O75197-1.2	T325C	Neutral	0.11
LRP5	O75197-1.2	T325D	Neutral	0.087
LRP5	O75197-1.2	T325E	Neutral	0.095
LRP5	O75197-1.2	T325F	Neutral	0.148
LRP5	O75197-1.2	T325G	Neutral	0.351
LRP5	O75197-1.2	T325H	Neutral	0.386
LRP5	O75197-1.2	T325I	Neutral	0.054
LRP5	O75197-1.2	T325K	Neutral	0.069
LRP5	O75197-1.2	T325L	Neutral	0.059
LRP5	O75197-1.2	T325M	Neutral	0.087
LRP5	O75197-1.2	T325N	Neutral	0.035
LRP5	O75197-1.2	T325P	Neutral	0.137
LRP5	O75197-1.2	T325Q	Neutral	0.132
LRP5	O75197-1.2	T325R	Neutral	0.066
LRP5	O75197-1.2	T325S	Neutral	0.019
LRP5	O75197-1.2	T325V	Neutral	0.032
LRP5	O75197-1.2	T325W	Neutral	0.099
LRP5	O75197-1.2	T325Y	Neutral	0.265
LRP5	O75197-1.2	G326A	Neutral	0.071
LRP5	O75197-1.2	G326C	Pathogenic	0.533
LRP5	O75197-1.2	G326D	Neutral	0.129
LRP5	O75197-1.2	G326E	Neutral	0.329
LRP5	O75197-1.2	G326F	Neutral	0.339
LRP5	O75197-1.2	G326H	Neutral	0.432
LRP5	O75197-1.2	G326I	Pathogenic	0.61
LRP5	O75197-1.2	G326K	Neutral	0.256
LRP5	O75197-1.2	G326L	Pathogenic	0.632
LRP5	O75197-1.2	G326M	Neutral	0.462
LRP5	O75197-1.2	G326N	Neutral	0.053
LRP5	O75197-1.2	G326P	Neutral	0.32
LRP5	O75197-1.2	G326Q	Neutral	0.415
LRP5	O75197-1.2	G326R	Neutral	0.249
LRP5	O75197-1.2	G326S	Neutral	0.088
LRP5	O75197-1.2	G326T	Neutral	0.415
LRP5	O75197-1.2	G326V	Neutral	0.473
LRP5	O75197-1.2	G326W	Neutral	0.096
LRP5	O75197-1.2	G326Y	Pathogenic	0.515
LRP5	O75197-1.2	V327A	Neutral	0.017
LRP5	O75197-1.2	V327C	Neutral	0.09
LRP5	O75197-1.2	V327D	Neutral	0.162
LRP5	O75197-1.2	V327E	Neutral	0.068
LRP5	O75197-1.2	V327F	Neutral	0.067
LRP5	O75197-1.2	V327G	Neutral	0.264
LRP5	O75197-1.2	V327H	Neutral	0.302
LRP5	O75197-1.2	V327I	Neutral	0.001
LRP5	O75197-1.2	V327K	Neutral	0.048
LRP5	O75197-1.2	V327L	Neutral	0.008
LRP5	O75197-1.2	V327M	Neutral	0.013
LRP5	O75197-1.2	V327N	Neutral	0.184
LRP5	O75197-1.2	V327P	Neutral	0.193
LRP5	O75197-1.2	V327Q	Neutral	0.095
LRP5	O75197-1.2	V327R	Neutral	0.13
LRP5	O75197-1.2	V327S	Neutral	0.106
LRP5	O75197-1.2	V327T	Neutral	0.017
LRP5	O75197-1.2	V327W	Neutral	0.296
LRP5	O75197-1.2	V327Y	Neutral	0.086
LRP5	O75197-1.2	Q328A	Neutral	0.002
LRP5	O75197-1.2	Q328C	Neutral	0.009
LRP5	O75197-1.2	Q328D	Neutral	0.001
LRP5	O75197-1.2	Q328E	Neutral	0.0
LRP5	O75197-1.2	Q328F	Neutral	0.004
LRP5	O75197-1.2	Q328G	Neutral	0.007
LRP5	O75197-1.2	Q328H	Neutral	0.001
LRP5	O75197-1.2	Q328I	Neutral	0.004
LRP5	O75197-1.2	Q328K	Neutral	0.0
LRP5	O75197-1.2	Q328L	Neutral	0.002
LRP5	O75197-1.2	Q328M	Neutral	0.0
LRP5	O75197-1.2	Q328N	Neutral	0.001
LRP5	O75197-1.2	Q328P	Neutral	0.001
LRP5	O75197-1.2	Q328R	Neutral	0.0
LRP5	O75197-1.2	Q328S	Neutral	0.001
LRP5	O75197-1.2	Q328T	Neutral	0.002
LRP5	O75197-1.2	Q328V	Neutral	0.002
LRP5	O75197-1.2	Q328W	Neutral	0.001
LRP5	O75197-1.2	Q328Y	Neutral	0.001
LRP5	O75197-1.2	L329A	Neutral	0.042
LRP5	O75197-1.2	L329C	Neutral	0.076
LRP5	O75197-1.2	L329D	Neutral	0.327
LRP5	O75197-1.2	L329E	Neutral	0.156
LRP5	O75197-1.2	L329F	Neutral	0.047
LRP5	O75197-1.2	L329G	Neutral	0.474
LRP5	O75197-1.2	L329H	Neutral	0.272
LRP5	O75197-1.2	L329I	Neutral	0.005
LRP5	O75197-1.2	L329K	Neutral	0.043
LRP5	O75197-1.2	L329M	Neutral	0.004
LRP5	O75197-1.2	L329N	Neutral	0.158
LRP5	O75197-1.2	L329P	Neutral	0.376
LRP5	O75197-1.2	L329Q	Neutral	0.082
LRP5	O75197-1.2	L329R	Neutral	0.041
LRP5	O75197-1.2	L329S	Neutral	0.089
LRP5	O75197-1.2	L329T	Neutral	0.042
LRP5	O75197-1.2	L329V	Neutral	0.011
LRP5	O75197-1.2	L329W	Neutral	0.225
LRP5	O75197-1.2	L329Y	Neutral	0.077
LRP5	O75197-1.2	Q330A	Neutral	0.0
LRP5	O75197-1.2	Q330C	Neutral	0.0
LRP5	O75197-1.2	Q330D	Neutral	0.0
LRP5	O75197-1.2	Q330E	Neutral	0.0
LRP5	O75197-1.2	Q330F	Neutral	0.0
LRP5	O75197-1.2	Q330G	Neutral	0.0
LRP5	O75197-1.2	Q330H	Neutral	0.0
LRP5	O75197-1.2	Q330I	Neutral	0.0
LRP5	O75197-1.2	Q330K	Neutral	0.0
LRP5	O75197-1.2	Q330L	Neutral	0.0
LRP5	O75197-1.2	Q330M	Neutral	0.0
LRP5	O75197-1.2	Q330N	Neutral	0.0
LRP5	O75197-1.2	Q330P	Neutral	0.0
LRP5	O75197-1.2	Q330R	Neutral	0.0
LRP5	O75197-1.2	Q330S	Neutral	0.0
LRP5	O75197-1.2	Q330T	Neutral	0.0
LRP5	O75197-1.2	Q330V	Neutral	0.0
LRP5	O75197-1.2	Q330W	Neutral	0.0
LRP5	O75197-1.2	Q330Y	Neutral	0.0
LRP5	O75197-1.2	D331A	Neutral	0.001
LRP5	O75197-1.2	D331C	Neutral	0.001
LRP5	O75197-1.2	D331E	Neutral	0.0
LRP5	O75197-1.2	D331F	Neutral	0.0
LRP5	O75197-1.2	D331G	Neutral	0.0
LRP5	O75197-1.2	D331H	Neutral	0.0
LRP5	O75197-1.2	D331I	Neutral	0.0
LRP5	O75197-1.2	D331K	Neutral	0.0
LRP5	O75197-1.2	D331L	Neutral	0.001
LRP5	O75197-1.2	D331M	Neutral	0.001
LRP5	O75197-1.2	D331N	Neutral	0.0
LRP5	O75197-1.2	D331P	Neutral	0.0
LRP5	O75197-1.2	D331Q	Neutral	0.0
LRP5	O75197-1.2	D331R	Neutral	0.001
LRP5	O75197-1.2	D331S	Neutral	0.0
LRP5	O75197-1.2	D331T	Neutral	0.0
LRP5	O75197-1.2	D331V	Neutral	0.001
LRP5	O75197-1.2	D331W	Neutral	0.001
LRP5	O75197-1.2	D331Y	Neutral	0.001
LRP5	O75197-1.2	N332A	Neutral	0.013
LRP5	O75197-1.2	N332C	Neutral	0.023
LRP5	O75197-1.2	N332D	Neutral	0.001
LRP5	O75197-1.2	N332E	Neutral	0.003
LRP5	O75197-1.2	N332F	Neutral	0.011
LRP5	O75197-1.2	N332G	Neutral	0.002
LRP5	O75197-1.2	N332H	Neutral	0.001
LRP5	O75197-1.2	N332I	Neutral	0.011
LRP5	O75197-1.2	N332K	Neutral	0.002
LRP5	O75197-1.2	N332L	Neutral	0.012
LRP5	O75197-1.2	N332M	Neutral	0.006
LRP5	O75197-1.2	N332P	Neutral	0.01
LRP5	O75197-1.2	N332Q	Neutral	0.002
LRP5	O75197-1.2	N332R	Neutral	0.002
LRP5	O75197-1.2	N332S	Neutral	0.001
LRP5	O75197-1.2	N332T	Neutral	0.002
LRP5	O75197-1.2	N332V	Neutral	0.019
LRP5	O75197-1.2	N332W	Neutral	0.02
LRP5	O75197-1.2	N332Y	Neutral	0.007
LRP5	O75197-1.2	G333A	Neutral	0.002
LRP5	O75197-1.2	G333C	Neutral	0.031
LRP5	O75197-1.2	G333D	Neutral	0.004
LRP5	O75197-1.2	G333E	Neutral	0.014
LRP5	O75197-1.2	G333F	Neutral	0.014
LRP5	O75197-1.2	G333H	Neutral	0.021
LRP5	O75197-1.2	G333I	Neutral	0.042
LRP5	O75197-1.2	G333K	Neutral	0.01
LRP5	O75197-1.2	G333L	Neutral	0.046
LRP5	O75197-1.2	G333M	Neutral	0.023
LRP5	O75197-1.2	G333N	Neutral	0.002
LRP5	O75197-1.2	G333P	Neutral	0.013
LRP5	O75197-1.2	G333Q	Neutral	0.019
LRP5	O75197-1.2	G333R	Neutral	0.009
LRP5	O75197-1.2	G333S	Neutral	0.003
LRP5	O75197-1.2	G333T	Neutral	0.019
LRP5	O75197-1.2	G333V	Neutral	0.024
LRP5	O75197-1.2	G333W	Neutral	0.003
LRP5	O75197-1.2	G333Y	Neutral	0.029
LRP5	O75197-1.2	R334A	Neutral	0.0
LRP5	O75197-1.2	R334C	Neutral	0.0
LRP5	O75197-1.2	R334D	Neutral	0.0
LRP5	O75197-1.2	R334E	Neutral	0.0
LRP5	O75197-1.2	R334F	Neutral	0.0
LRP5	O75197-1.2	R334G	Neutral	0.0
LRP5	O75197-1.2	R334H	Neutral	0.0
LRP5	O75197-1.2	R334I	Neutral	0.0
LRP5	O75197-1.2	R334K	Neutral	0.0
LRP5	O75197-1.2	R334L	Neutral	0.0
LRP5	O75197-1.2	R334M	Neutral	0.0
LRP5	O75197-1.2	R334N	Neutral	0.0
LRP5	O75197-1.2	R334P	Neutral	0.0
LRP5	O75197-1.2	R334Q	Neutral	0.0
LRP5	O75197-1.2	R334S	Neutral	0.0
LRP5	O75197-1.2	R334T	Neutral	0.0
LRP5	O75197-1.2	R334V	Neutral	0.0
LRP5	O75197-1.2	R334W	Neutral	0.0
LRP5	O75197-1.2	R334Y	Neutral	0.0
LRP5	O75197-1.2	T335A	Neutral	0.042
LRP5	O75197-1.2	T335C	Neutral	0.07
LRP5	O75197-1.2	T335D	Neutral	0.055
LRP5	O75197-1.2	T335E	Neutral	0.06
LRP5	O75197-1.2	T335F	Neutral	0.096
LRP5	O75197-1.2	T335G	Neutral	0.248
LRP5	O75197-1.2	T335H	Neutral	0.277
LRP5	O75197-1.2	T335I	Neutral	0.034
LRP5	O75197-1.2	T335K	Neutral	0.043
LRP5	O75197-1.2	T335L	Neutral	0.037
LRP5	O75197-1.2	T335M	Neutral	0.055
LRP5	O75197-1.2	T335N	Neutral	0.022
LRP5	O75197-1.2	T335P	Neutral	0.088
LRP5	O75197-1.2	T335Q	Neutral	0.085
LRP5	O75197-1.2	T335R	Neutral	0.042
LRP5	O75197-1.2	T335S	Neutral	0.012
LRP5	O75197-1.2	T335V	Neutral	0.02
LRP5	O75197-1.2	T335W	Neutral	0.063
LRP5	O75197-1.2	T335Y	Neutral	0.18
LRP5	O75197-1.2	C336A	Pathogenic	0.981
LRP5	O75197-1.2	C336D	Pathogenic	0.998
LRP5	O75197-1.2	C336E	Pathogenic	0.999
LRP5	O75197-1.2	C336F	Pathogenic	0.997
LRP5	O75197-1.2	C336G	Pathogenic	0.999
LRP5	O75197-1.2	C336H	Pathogenic	0.999
LRP5	O75197-1.2	C336I	Pathogenic	0.992
LRP5	O75197-1.2	C336K	Pathogenic	0.998
LRP5	O75197-1.2	C336L	Pathogenic	0.993
LRP5	O75197-1.2	C336M	Pathogenic	0.995
LRP5	O75197-1.2	C336N	Pathogenic	0.998
LRP5	O75197-1.2	C336P	Pathogenic	1.0
LRP5	O75197-1.2	C336Q	Pathogenic	0.999
LRP5	O75197-1.2	C336R	Pathogenic	0.998
LRP5	O75197-1.2	C336S	Pathogenic	0.991
LRP5	O75197-1.2	C336T	Pathogenic	0.993
LRP5	O75197-1.2	C336V	Pathogenic	0.996
LRP5	O75197-1.2	C336W	Pathogenic	0.996
LRP5	O75197-1.2	C336Y	Pathogenic	0.999
LRP5	O75197-1.2	K337A	Neutral	0.002
LRP5	O75197-1.2	K337C	Neutral	0.01
LRP5	O75197-1.2	K337D	Neutral	0.005
LRP5	O75197-1.2	K337E	Neutral	0.001
LRP5	O75197-1.2	K337F	Neutral	0.005
LRP5	O75197-1.2	K337G	Neutral	0.007
LRP5	O75197-1.2	K337H	Neutral	0.002
LRP5	O75197-1.2	K337I	Neutral	0.005
LRP5	O75197-1.2	K337L	Neutral	0.002
LRP5	O75197-1.2	K337M	Neutral	0.001
LRP5	O75197-1.2	K337N	Neutral	0.001
LRP5	O75197-1.2	K337P	Neutral	0.001
LRP5	O75197-1.2	K337Q	Neutral	0.0
LRP5	O75197-1.2	K337R	Neutral	0.0
LRP5	O75197-1.2	K337S	Neutral	0.001
LRP5	O75197-1.2	K337T	Neutral	0.002
LRP5	O75197-1.2	K337V	Neutral	0.003
LRP5	O75197-1.2	K337W	Neutral	0.003
LRP5	O75197-1.2	K337Y	Neutral	0.004
LRP5	O75197-1.2	A338C	Neutral	0.0
LRP5	O75197-1.2	A338D	Neutral	0.0
LRP5	O75197-1.2	A338E	Neutral	0.0
LRP5	O75197-1.2	A338F	Neutral	0.0
LRP5	O75197-1.2	A338G	Neutral	0.0
LRP5	O75197-1.2	A338H	Neutral	0.0
LRP5	O75197-1.2	A338I	Neutral	0.0
LRP5	O75197-1.2	A338K	Neutral	0.0
LRP5	O75197-1.2	A338L	Neutral	0.0
LRP5	O75197-1.2	A338M	Neutral	0.0
LRP5	O75197-1.2	A338N	Neutral	0.0
LRP5	O75197-1.2	A338P	Neutral	0.0
LRP5	O75197-1.2	A338Q	Neutral	0.0
LRP5	O75197-1.2	A338R	Neutral	0.0
LRP5	O75197-1.2	A338S	Neutral	0.0
LRP5	O75197-1.2	A338T	Neutral	0.0
LRP5	O75197-1.2	A338V	Neutral	0.0
LRP5	O75197-1.2	A338W	Neutral	0.0
LRP5	O75197-1.2	A338Y	Neutral	0.0
LRP5	O75197-1.2	G339A	Neutral	0.035
LRP5	O75197-1.2	G339C	Neutral	0.349
LRP5	O75197-1.2	G339D	Neutral	0.065
LRP5	O75197-1.2	G339E	Neutral	0.188
LRP5	O75197-1.2	G339F	Neutral	0.194
LRP5	O75197-1.2	G339H	Neutral	0.264
LRP5	O75197-1.2	G339I	Neutral	0.424
LRP5	O75197-1.2	G339K	Neutral	0.139
LRP5	O75197-1.2	G339L	Neutral	0.447
LRP5	O75197-1.2	G339M	Neutral	0.288
LRP5	O75197-1.2	G339N	Neutral	0.026
LRP5	O75197-1.2	G339P	Neutral	0.181
LRP5	O75197-1.2	G339Q	Neutral	0.25
LRP5	O75197-1.2	G339R	Neutral	0.135
LRP5	O75197-1.2	G339S	Neutral	0.043
LRP5	O75197-1.2	G339T	Neutral	0.25
LRP5	O75197-1.2	G339V	Neutral	0.297
LRP5	O75197-1.2	G339W	Neutral	0.048
LRP5	O75197-1.2	G339Y	Neutral	0.334
LRP5	O75197-1.2	A340C	Neutral	0.011
LRP5	O75197-1.2	A340D	Neutral	0.067
LRP5	O75197-1.2	A340E	Neutral	0.025
LRP5	O75197-1.2	A340F	Neutral	0.044
LRP5	O75197-1.2	A340G	Neutral	0.015
LRP5	O75197-1.2	A340H	Neutral	0.133
LRP5	O75197-1.2	A340I	Neutral	0.015
LRP5	O75197-1.2	A340K	Neutral	0.018
LRP5	O75197-1.2	A340L	Neutral	0.017
LRP5	O75197-1.2	A340M	Neutral	0.025
LRP5	O75197-1.2	A340N	Neutral	0.076
LRP5	O75197-1.2	A340P	Neutral	0.041
LRP5	O75197-1.2	A340Q	Neutral	0.036
LRP5	O75197-1.2	A340R	Neutral	0.017
LRP5	O75197-1.2	A340S	Neutral	0.005
LRP5	O75197-1.2	A340T	Neutral	0.019
LRP5	O75197-1.2	A340V	Neutral	0.009
LRP5	O75197-1.2	A340W	Neutral	0.082
LRP5	O75197-1.2	A340Y	Neutral	0.088
LRP5	O75197-1.2	E341A	Neutral	0.351
LRP5	O75197-1.2	E341C	Pathogenic	0.896
LRP5	O75197-1.2	E341D	Neutral	0.04
LRP5	O75197-1.2	E341F	Pathogenic	0.577
LRP5	O75197-1.2	E341G	Pathogenic	0.677
LRP5	O75197-1.2	E341H	Neutral	0.18
LRP5	O75197-1.2	E341I	Pathogenic	0.578
LRP5	O75197-1.2	E341K	Neutral	0.092
LRP5	O75197-1.2	E341L	Pathogenic	0.6
LRP5	O75197-1.2	E341M	Neutral	0.429
LRP5	O75197-1.2	E341N	Neutral	0.295
LRP5	O75197-1.2	E341P	Neutral	0.28
LRP5	O75197-1.2	E341Q	Neutral	0.032
LRP5	O75197-1.2	E341R	Neutral	0.23
LRP5	O75197-1.2	E341S	Neutral	0.196
LRP5	O75197-1.2	E341T	Neutral	0.371
LRP5	O75197-1.2	E341V	Neutral	0.436
LRP5	O75197-1.2	E341W	Neutral	0.463
LRP5	O75197-1.2	E341Y	Neutral	0.482
LRP5	O75197-1.2	E342A	Pathogenic	0.567
LRP5	O75197-1.2	E342C	Pathogenic	0.954
LRP5	O75197-1.2	E342D	Neutral	0.091
LRP5	O75197-1.2	E342F	Pathogenic	0.768
LRP5	O75197-1.2	E342G	Pathogenic	0.836
LRP5	O75197-1.2	E342H	Neutral	0.347
LRP5	O75197-1.2	E342I	Pathogenic	0.768
LRP5	O75197-1.2	E342K	Neutral	0.198
LRP5	O75197-1.2	E342L	Pathogenic	0.784
LRP5	O75197-1.2	E342M	Pathogenic	0.645
LRP5	O75197-1.2	E342N	Pathogenic	0.504
LRP5	O75197-1.2	E342P	Neutral	0.485
LRP5	O75197-1.2	E342Q	Neutral	0.073
LRP5	O75197-1.2	E342R	Neutral	0.42
LRP5	O75197-1.2	E342S	Neutral	0.371
LRP5	O75197-1.2	E342T	Pathogenic	0.588
LRP5	O75197-1.2	E342V	Pathogenic	0.652
LRP5	O75197-1.2	E342W	Pathogenic	0.676
LRP5	O75197-1.2	E342Y	Pathogenic	0.693
LRP5	O75197-1.2	V343A	Neutral	0.112
LRP5	O75197-1.2	V343C	Neutral	0.42
LRP5	O75197-1.2	V343D	Pathogenic	0.585
LRP5	O75197-1.2	V343E	Neutral	0.347
LRP5	O75197-1.2	V343F	Neutral	0.345
LRP5	O75197-1.2	V343G	Pathogenic	0.724
LRP5	O75197-1.2	V343H	Pathogenic	0.76
LRP5	O75197-1.2	V343I	Neutral	0.006
LRP5	O75197-1.2	V343K	Neutral	0.271
LRP5	O75197-1.2	V343L	Neutral	0.059
LRP5	O75197-1.2	V343M	Neutral	0.087
LRP5	O75197-1.2	V343N	Pathogenic	0.623
LRP5	O75197-1.2	V343P	Pathogenic	0.637
LRP5	O75197-1.2	V343Q	Neutral	0.433
LRP5	O75197-1.2	V343R	Pathogenic	0.522
LRP5	O75197-1.2	V343S	Neutral	0.465
LRP5	O75197-1.2	V343T	Neutral	0.112
LRP5	O75197-1.2	V343W	Pathogenic	0.755
LRP5	O75197-1.2	V343Y	Neutral	0.409
LRP5	O75197-1.2	L344A	Pathogenic	0.965
LRP5	O75197-1.2	L344C	Pathogenic	0.981
LRP5	O75197-1.2	L344D	Pathogenic	0.997
LRP5	O75197-1.2	L344E	Pathogenic	0.992
LRP5	O75197-1.2	L344F	Pathogenic	0.969
LRP5	O75197-1.2	L344G	Pathogenic	0.998
LRP5	O75197-1.2	L344H	Pathogenic	0.996
LRP5	O75197-1.2	L344I	Pathogenic	0.773
LRP5	O75197-1.2	L344K	Pathogenic	0.966
LRP5	O75197-1.2	L344M	Pathogenic	0.71
LRP5	O75197-1.2	L344N	Pathogenic	0.992
LRP5	O75197-1.2	L344P	Pathogenic	0.997
LRP5	O75197-1.2	L344Q	Pathogenic	0.983
LRP5	O75197-1.2	L344R	Pathogenic	0.965
LRP5	O75197-1.2	L344S	Pathogenic	0.984
LRP5	O75197-1.2	L344T	Pathogenic	0.965
LRP5	O75197-1.2	L344V	Pathogenic	0.877
LRP5	O75197-1.2	L344W	Pathogenic	0.995
LRP5	O75197-1.2	L344Y	Pathogenic	0.981
LRP5	O75197-1.2	L345A	Pathogenic	0.939
LRP5	O75197-1.2	L345C	Pathogenic	0.967
LRP5	O75197-1.2	L345D	Pathogenic	0.994
LRP5	O75197-1.2	L345E	Pathogenic	0.985
LRP5	O75197-1.2	L345F	Pathogenic	0.946
LRP5	O75197-1.2	L345G	Pathogenic	0.997
LRP5	O75197-1.2	L345H	Pathogenic	0.992
LRP5	O75197-1.2	L345I	Pathogenic	0.655
LRP5	O75197-1.2	L345K	Pathogenic	0.941
LRP5	O75197-1.2	L345M	Pathogenic	0.578
LRP5	O75197-1.2	L345N	Pathogenic	0.985
LRP5	O75197-1.2	L345P	Pathogenic	0.995
LRP5	O75197-1.2	L345Q	Pathogenic	0.969
LRP5	O75197-1.2	L345R	Pathogenic	0.939
LRP5	O75197-1.2	L345S	Pathogenic	0.972
LRP5	O75197-1.2	L345T	Pathogenic	0.939
LRP5	O75197-1.2	L345V	Pathogenic	0.8
LRP5	O75197-1.2	L345W	Pathogenic	0.99
LRP5	O75197-1.2	L345Y	Pathogenic	0.967
LRP5	O75197-1.2	L346A	Pathogenic	0.898
LRP5	O75197-1.2	L346C	Pathogenic	0.943
LRP5	O75197-1.2	L346D	Pathogenic	0.99
LRP5	O75197-1.2	L346E	Pathogenic	0.974
LRP5	O75197-1.2	L346F	Pathogenic	0.909
LRP5	O75197-1.2	L346G	Pathogenic	0.995
LRP5	O75197-1.2	L346H	Pathogenic	0.987
LRP5	O75197-1.2	L346I	Pathogenic	0.52
LRP5	O75197-1.2	L346K	Pathogenic	0.9
LRP5	O75197-1.2	L346M	Neutral	0.438
LRP5	O75197-1.2	L346N	Pathogenic	0.974
LRP5	O75197-1.2	L346P	Pathogenic	0.992
LRP5	O75197-1.2	L346Q	Pathogenic	0.947
LRP5	O75197-1.2	L346R	Pathogenic	0.897
LRP5	O75197-1.2	L346S	Pathogenic	0.952
LRP5	O75197-1.2	L346T	Pathogenic	0.897
LRP5	O75197-1.2	L346V	Pathogenic	0.695
LRP5	O75197-1.2	L346W	Pathogenic	0.983
LRP5	O75197-1.2	L346Y	Pathogenic	0.944
LRP5	O75197-1.2	A347C	Pathogenic	0.883
LRP5	O75197-1.2	A347D	Pathogenic	0.98
LRP5	O75197-1.2	A347E	Pathogenic	0.945
LRP5	O75197-1.2	A347F	Pathogenic	0.969
LRP5	O75197-1.2	A347G	Pathogenic	0.913
LRP5	O75197-1.2	A347H	Pathogenic	0.99
LRP5	O75197-1.2	A347I	Pathogenic	0.912
LRP5	O75197-1.2	A347K	Pathogenic	0.924
LRP5	O75197-1.2	A347L	Pathogenic	0.919
LRP5	O75197-1.2	A347M	Pathogenic	0.945
LRP5	O75197-1.2	A347N	Pathogenic	0.982
LRP5	O75197-1.2	A347P	Pathogenic	0.966
LRP5	O75197-1.2	A347Q	Pathogenic	0.962
LRP5	O75197-1.2	A347R	Pathogenic	0.921
LRP5	O75197-1.2	A347S	Pathogenic	0.773
LRP5	O75197-1.2	A347T	Pathogenic	0.929
LRP5	O75197-1.2	A347V	Pathogenic	0.856
LRP5	O75197-1.2	A347W	Pathogenic	0.984
LRP5	O75197-1.2	A347Y	Pathogenic	0.985
LRP5	O75197-1.2	R348A	Pathogenic	0.923
LRP5	O75197-1.2	R348C	Pathogenic	0.984
LRP5	O75197-1.2	R348D	Pathogenic	0.99
LRP5	O75197-1.2	R348E	Pathogenic	0.908
LRP5	O75197-1.2	R348F	Pathogenic	0.971
LRP5	O75197-1.2	R348G	Pathogenic	0.979
LRP5	O75197-1.2	R348H	Pathogenic	0.834
LRP5	O75197-1.2	R348I	Pathogenic	0.97
LRP5	O75197-1.2	R348K	Pathogenic	0.603
LRP5	O75197-1.2	R348L	Pathogenic	0.92
LRP5	O75197-1.2	R348M	Pathogenic	0.852
LRP5	O75197-1.2	R348N	Pathogenic	0.903
LRP5	O75197-1.2	R348P	Pathogenic	0.963
LRP5	O75197-1.2	R348Q	Pathogenic	0.692
LRP5	O75197-1.2	R348S	Pathogenic	0.943
LRP5	O75197-1.2	R348T	Pathogenic	0.929
LRP5	O75197-1.2	R348V	Pathogenic	0.981
LRP5	O75197-1.2	R348W	Pathogenic	0.956
LRP5	O75197-1.2	R348Y	Pathogenic	0.958
LRP5	O75197-1.2	R349A	Pathogenic	0.979
LRP5	O75197-1.2	R349C	Pathogenic	0.996
LRP5	O75197-1.2	R349D	Pathogenic	0.997
LRP5	O75197-1.2	R349E	Pathogenic	0.974
LRP5	O75197-1.2	R349F	Pathogenic	0.992
LRP5	O75197-1.2	R349G	Pathogenic	0.994
LRP5	O75197-1.2	R349H	Pathogenic	0.951
LRP5	O75197-1.2	R349I	Pathogenic	0.992
LRP5	O75197-1.2	R349K	Pathogenic	0.854
LRP5	O75197-1.2	R349L	Pathogenic	0.978
LRP5	O75197-1.2	R349M	Pathogenic	0.957
LRP5	O75197-1.2	R349N	Pathogenic	0.973
LRP5	O75197-1.2	R349P	Pathogenic	0.99
LRP5	O75197-1.2	R349Q	Pathogenic	0.896
LRP5	O75197-1.2	R349S	Pathogenic	0.985
LRP5	O75197-1.2	R349T	Pathogenic	0.981
LRP5	O75197-1.2	R349V	Pathogenic	0.995
LRP5	O75197-1.2	R349W	Pathogenic	0.988
LRP5	O75197-1.2	R349Y	Pathogenic	0.989
LRP5	O75197-1.2	T350A	Pathogenic	0.831
LRP5	O75197-1.2	T350C	Pathogenic	0.894
LRP5	O75197-1.2	T350D	Pathogenic	0.867
LRP5	O75197-1.2	T350E	Pathogenic	0.877
LRP5	O75197-1.2	T350F	Pathogenic	0.922
LRP5	O75197-1.2	T350G	Pathogenic	0.973
LRP5	O75197-1.2	T350H	Pathogenic	0.977
LRP5	O75197-1.2	T350I	Pathogenic	0.796
LRP5	O75197-1.2	T350K	Pathogenic	0.834
LRP5	O75197-1.2	T350L	Pathogenic	0.81
LRP5	O75197-1.2	T350M	Pathogenic	0.867
LRP5	O75197-1.2	T350N	Pathogenic	0.713
LRP5	O75197-1.2	T350P	Pathogenic	0.915
LRP5	O75197-1.2	T350Q	Pathogenic	0.912
LRP5	O75197-1.2	T350R	Pathogenic	0.829
LRP5	O75197-1.2	T350S	Pathogenic	0.568
LRP5	O75197-1.2	T350V	Pathogenic	0.69
LRP5	O75197-1.2	T350W	Pathogenic	0.882
LRP5	O75197-1.2	T350Y	Pathogenic	0.961
LRP5	O75197-1.2	D351A	Pathogenic	0.972
LRP5	O75197-1.2	D351C	Pathogenic	0.984
LRP5	O75197-1.2	D351E	Neutral	0.492
LRP5	O75197-1.2	D351F	Pathogenic	0.965
LRP5	O75197-1.2	D351G	Pathogenic	0.937
LRP5	O75197-1.2	D351H	Pathogenic	0.931
LRP5	O75197-1.2	D351I	Pathogenic	0.965
LRP5	O75197-1.2	D351K	Pathogenic	0.96
LRP5	O75197-1.2	D351L	Pathogenic	0.989
LRP5	O75197-1.2	D351M	Pathogenic	0.979
LRP5	O75197-1.2	D351N	Pathogenic	0.744
LRP5	O75197-1.2	D351P	Pathogenic	0.893
LRP5	O75197-1.2	D351Q	Pathogenic	0.859
LRP5	O75197-1.2	D351R	Pathogenic	0.986
LRP5	O75197-1.2	D351S	Pathogenic	0.839
LRP5	O75197-1.2	D351T	Pathogenic	0.926
LRP5	O75197-1.2	D351V	Pathogenic	0.98
LRP5	O75197-1.2	D351W	Pathogenic	0.982
LRP5	O75197-1.2	D351Y	Pathogenic	0.983
LRP5	O75197-1.2	L352A	Pathogenic	0.9
LRP5	O75197-1.2	L352C	Pathogenic	0.944
LRP5	O75197-1.2	L352D	Pathogenic	0.99
LRP5	O75197-1.2	L352E	Pathogenic	0.975
LRP5	O75197-1.2	L352F	Pathogenic	0.911
LRP5	O75197-1.2	L352G	Pathogenic	0.995
LRP5	O75197-1.2	L352H	Pathogenic	0.987
LRP5	O75197-1.2	L352I	Pathogenic	0.526
LRP5	O75197-1.2	L352K	Pathogenic	0.902
LRP5	O75197-1.2	L352M	Neutral	0.444
LRP5	O75197-1.2	L352N	Pathogenic	0.975
LRP5	O75197-1.2	L352P	Pathogenic	0.992
LRP5	O75197-1.2	L352Q	Pathogenic	0.948
LRP5	O75197-1.2	L352R	Pathogenic	0.899
LRP5	O75197-1.2	L352S	Pathogenic	0.953
LRP5	O75197-1.2	L352T	Pathogenic	0.9
LRP5	O75197-1.2	L352V	Pathogenic	0.7
LRP5	O75197-1.2	L352W	Pathogenic	0.984
LRP5	O75197-1.2	L352Y	Pathogenic	0.945
LRP5	O75197-1.2	R353A	Pathogenic	0.944
LRP5	O75197-1.2	R353C	Pathogenic	0.989
LRP5	O75197-1.2	R353D	Pathogenic	0.993
LRP5	O75197-1.2	R353E	Pathogenic	0.933
LRP5	O75197-1.2	R353F	Pathogenic	0.979
LRP5	O75197-1.2	R353G	Pathogenic	0.985
LRP5	O75197-1.2	R353H	Pathogenic	0.876
LRP5	O75197-1.2	R353I	Pathogenic	0.978
LRP5	O75197-1.2	R353K	Pathogenic	0.681
LRP5	O75197-1.2	R353L	Pathogenic	0.942
LRP5	O75197-1.2	R353M	Pathogenic	0.89
LRP5	O75197-1.2	R353N	Pathogenic	0.929
LRP5	O75197-1.2	R353P	Pathogenic	0.974
LRP5	O75197-1.2	R353Q	Pathogenic	0.76
LRP5	O75197-1.2	R353S	Pathogenic	0.959
LRP5	O75197-1.2	R353T	Pathogenic	0.949
LRP5	O75197-1.2	R353V	Pathogenic	0.987
LRP5	O75197-1.2	R353W	Pathogenic	0.968
LRP5	O75197-1.2	R353Y	Pathogenic	0.97
LRP5	O75197-1.2	R354A	Pathogenic	0.952
LRP5	O75197-1.2	R354C	Pathogenic	0.99
LRP5	O75197-1.2	R354D	Pathogenic	0.994
LRP5	O75197-1.2	R354E	Pathogenic	0.942
LRP5	O75197-1.2	R354F	Pathogenic	0.982
LRP5	O75197-1.2	R354G	Pathogenic	0.987
LRP5	O75197-1.2	R354H	Pathogenic	0.892
LRP5	O75197-1.2	R354I	Pathogenic	0.981
LRP5	O75197-1.2	R354K	Pathogenic	0.715
LRP5	O75197-1.2	R354L	Pathogenic	0.95
LRP5	O75197-1.2	R354M	Pathogenic	0.905
LRP5	O75197-1.2	R354N	Pathogenic	0.939
LRP5	O75197-1.2	R354P	Pathogenic	0.977
LRP5	O75197-1.2	R354Q	Pathogenic	0.788
LRP5	O75197-1.2	R354S	Pathogenic	0.965
LRP5	O75197-1.2	R354T	Pathogenic	0.956
LRP5	O75197-1.2	R354V	Pathogenic	0.989
LRP5	O75197-1.2	R354W	Pathogenic	0.973
LRP5	O75197-1.2	R354Y	Pathogenic	0.974
LRP5	O75197-1.2	I355A	Pathogenic	0.974
LRP5	O75197-1.2	I355C	Pathogenic	0.986
LRP5	O75197-1.2	I355D	Pathogenic	0.993
LRP5	O75197-1.2	I355E	Pathogenic	0.994
LRP5	O75197-1.2	I355F	Pathogenic	0.98
LRP5	O75197-1.2	I355G	Pathogenic	0.999
LRP5	O75197-1.2	I355H	Pathogenic	0.997
LRP5	O75197-1.2	I355K	Pathogenic	0.992
LRP5	O75197-1.2	I355L	Pathogenic	0.835
LRP5	O75197-1.2	I355M	Pathogenic	0.91
LRP5	O75197-1.2	I355N	Pathogenic	0.994
LRP5	O75197-1.2	I355P	Pathogenic	0.998
LRP5	O75197-1.2	I355Q	Pathogenic	0.996
LRP5	O75197-1.2	I355R	Pathogenic	0.991
LRP5	O75197-1.2	I355S	Pathogenic	0.988
LRP5	O75197-1.2	I355T	Pathogenic	0.974
LRP5	O75197-1.2	I355V	Pathogenic	0.511
LRP5	O75197-1.2	I355W	Pathogenic	0.999
LRP5	O75197-1.2	I355Y	Pathogenic	0.986
LRP5	O75197-1.2	S356A	Pathogenic	0.899
LRP5	O75197-1.2	S356C	Pathogenic	0.978
LRP5	O75197-1.2	S356D	Pathogenic	0.95
LRP5	O75197-1.2	S356E	Pathogenic	0.954
LRP5	O75197-1.2	S356F	Pathogenic	0.984
LRP5	O75197-1.2	S356G	Pathogenic	0.972
LRP5	O75197-1.2	S356H	Pathogenic	0.989
LRP5	O75197-1.2	S356I	Pathogenic	0.984
LRP5	O75197-1.2	S356K	Pathogenic	0.935
LRP5	O75197-1.2	S356L	Pathogenic	0.985
LRP5	O75197-1.2	S356M	Pathogenic	0.971
LRP5	O75197-1.2	S356N	Pathogenic	0.877
LRP5	O75197-1.2	S356P	Pathogenic	0.983
LRP5	O75197-1.2	S356Q	Pathogenic	0.967
LRP5	O75197-1.2	S356R	Pathogenic	0.977
LRP5	O75197-1.2	S356T	Pathogenic	0.902
LRP5	O75197-1.2	S356V	Pathogenic	0.991
LRP5	O75197-1.2	S356W	Pathogenic	0.992
LRP5	O75197-1.2	S356Y	Pathogenic	0.992
LRP5	O75197-1.2	L357A	Pathogenic	0.975
LRP5	O75197-1.2	L357C	Pathogenic	0.986
LRP5	O75197-1.2	L357D	Pathogenic	0.998
LRP5	O75197-1.2	L357E	Pathogenic	0.994
LRP5	O75197-1.2	L357F	Pathogenic	0.978
LRP5	O75197-1.2	L357G	Pathogenic	0.999
LRP5	O75197-1.2	L357H	Pathogenic	0.997
LRP5	O75197-1.2	L357I	Pathogenic	0.825
LRP5	O75197-1.2	L357K	Pathogenic	0.975
LRP5	O75197-1.2	L357M	Pathogenic	0.773
LRP5	O75197-1.2	L357N	Pathogenic	0.994
LRP5	O75197-1.2	L357P	Pathogenic	0.998
LRP5	O75197-1.2	L357Q	Pathogenic	0.987
LRP5	O75197-1.2	L357R	Pathogenic	0.974
LRP5	O75197-1.2	L357S	Pathogenic	0.989
LRP5	O75197-1.2	L357T	Pathogenic	0.974
LRP5	O75197-1.2	L357V	Pathogenic	0.908
LRP5	O75197-1.2	L357W	Pathogenic	0.996
LRP5	O75197-1.2	L357Y	Pathogenic	0.987
LRP5	O75197-1.2	D358A	Pathogenic	0.992
LRP5	O75197-1.2	D358C	Pathogenic	0.995
LRP5	O75197-1.2	D358E	Pathogenic	0.775
LRP5	O75197-1.2	D358F	Pathogenic	0.99
LRP5	O75197-1.2	D358G	Pathogenic	0.981
LRP5	O75197-1.2	D358H	Pathogenic	0.98
LRP5	O75197-1.2	D358I	Pathogenic	0.99
LRP5	O75197-1.2	D358K	Pathogenic	0.988
LRP5	O75197-1.2	D358L	Pathogenic	0.997
LRP5	O75197-1.2	D358M	Pathogenic	0.994
LRP5	O75197-1.2	D358N	Pathogenic	0.912
LRP5	O75197-1.2	D358P	Pathogenic	0.967
LRP5	O75197-1.2	D358Q	Pathogenic	0.956
LRP5	O75197-1.2	D358R	Pathogenic	0.996
LRP5	O75197-1.2	D358S	Pathogenic	0.949
LRP5	O75197-1.2	D358T	Pathogenic	0.978
LRP5	O75197-1.2	D358V	Pathogenic	0.994
LRP5	O75197-1.2	D358W	Pathogenic	0.995
LRP5	O75197-1.2	D358Y	Pathogenic	0.995
LRP5	O75197-1.2	T359A	Neutral	0.374
LRP5	O75197-1.2	T359C	Pathogenic	0.506
LRP5	O75197-1.2	T359D	Neutral	0.441
LRP5	O75197-1.2	T359E	Neutral	0.465
LRP5	O75197-1.2	T359F	Pathogenic	0.589
LRP5	O75197-1.2	T359G	Pathogenic	0.817
LRP5	O75197-1.2	T359H	Pathogenic	0.838
LRP5	O75197-1.2	T359I	Neutral	0.321
LRP5	O75197-1.2	T359K	Neutral	0.378
LRP5	O75197-1.2	T359L	Neutral	0.341
LRP5	O75197-1.2	T359M	Neutral	0.441
LRP5	O75197-1.2	T359N	Neutral	0.231
LRP5	O75197-1.2	T359P	Pathogenic	0.566
LRP5	O75197-1.2	T359Q	Pathogenic	0.556
LRP5	O75197-1.2	T359R	Neutral	0.37
LRP5	O75197-1.2	T359S	Neutral	0.138
LRP5	O75197-1.2	T359V	Neutral	0.213
LRP5	O75197-1.2	T359W	Neutral	0.475
LRP5	O75197-1.2	T359Y	Pathogenic	0.748
LRP5	O75197-1.2	P360A	Pathogenic	0.989
LRP5	O75197-1.2	P360C	Pathogenic	0.999
LRP5	O75197-1.2	P360D	Pathogenic	0.973
LRP5	O75197-1.2	P360E	Pathogenic	0.975
LRP5	O75197-1.2	P360F	Pathogenic	0.999
LRP5	O75197-1.2	P360G	Pathogenic	0.995
LRP5	O75197-1.2	P360H	Pathogenic	0.996
LRP5	O75197-1.2	P360I	Pathogenic	0.998
LRP5	O75197-1.2	P360K	Pathogenic	0.964
LRP5	O75197-1.2	P360L	Pathogenic	0.998
LRP5	O75197-1.2	P360M	Pathogenic	0.996
LRP5	O75197-1.2	P360N	Pathogenic	0.992
LRP5	O75197-1.2	P360Q	Pathogenic	0.982
LRP5	O75197-1.2	P360R	Pathogenic	0.988
LRP5	O75197-1.2	P360S	Pathogenic	0.985
LRP5	O75197-1.2	P360T	Pathogenic	0.989
LRP5	O75197-1.2	P360V	Pathogenic	0.996
LRP5	O75197-1.2	P360W	Pathogenic	0.999
LRP5	O75197-1.2	P360Y	Pathogenic	0.999
LRP5	O75197-1.2	D361A	Pathogenic	0.995
LRP5	O75197-1.2	D361C	Pathogenic	0.997
LRP5	O75197-1.2	D361E	Pathogenic	0.834
LRP5	O75197-1.2	D361F	Pathogenic	0.993
LRP5	O75197-1.2	D361G	Pathogenic	0.987
LRP5	O75197-1.2	D361H	Pathogenic	0.986
LRP5	O75197-1.2	D361I	Pathogenic	0.993
LRP5	O75197-1.2	D361K	Pathogenic	0.992
LRP5	O75197-1.2	D361L	Pathogenic	0.998
LRP5	O75197-1.2	D361M	Pathogenic	0.996
LRP5	O75197-1.2	D361N	Pathogenic	0.938
LRP5	O75197-1.2	D361P	Pathogenic	0.977
LRP5	O75197-1.2	D361Q	Pathogenic	0.97
LRP5	O75197-1.2	D361R	Pathogenic	0.997
LRP5	O75197-1.2	D361S	Pathogenic	0.965
LRP5	O75197-1.2	D361T	Pathogenic	0.985
LRP5	O75197-1.2	D361V	Pathogenic	0.996
LRP5	O75197-1.2	D361W	Pathogenic	0.996
LRP5	O75197-1.2	D361Y	Pathogenic	0.997
LRP5	O75197-1.2	F362A	Pathogenic	0.951
LRP5	O75197-1.2	F362C	Pathogenic	0.973
LRP5	O75197-1.2	F362D	Pathogenic	0.959
LRP5	O75197-1.2	F362E	Pathogenic	0.964
LRP5	O75197-1.2	F362G	Pathogenic	0.977
LRP5	O75197-1.2	F362H	Pathogenic	0.855
LRP5	O75197-1.2	F362I	Pathogenic	0.895
LRP5	O75197-1.2	F362K	Pathogenic	0.954
LRP5	O75197-1.2	F362L	Pathogenic	0.888
LRP5	O75197-1.2	F362M	Pathogenic	0.839
LRP5	O75197-1.2	F362N	Pathogenic	0.965
LRP5	O75197-1.2	F362P	Pathogenic	0.996
LRP5	O75197-1.2	F362Q	Pathogenic	0.975
LRP5	O75197-1.2	F362R	Pathogenic	0.952
LRP5	O75197-1.2	F362S	Pathogenic	0.935
LRP5	O75197-1.2	F362T	Pathogenic	0.951
LRP5	O75197-1.2	F362V	Pathogenic	0.938
LRP5	O75197-1.2	F362W	Pathogenic	0.645
LRP5	O75197-1.2	F362Y	Neutral	0.128
LRP5	O75197-1.2	T363A	Pathogenic	0.982
LRP5	O75197-1.2	T363C	Pathogenic	0.99
LRP5	O75197-1.2	T363D	Pathogenic	0.987
LRP5	O75197-1.2	T363E	Pathogenic	0.988
LRP5	O75197-1.2	T363F	Pathogenic	0.993
LRP5	O75197-1.2	T363G	Pathogenic	0.998
LRP5	O75197-1.2	T363H	Pathogenic	0.998
LRP5	O75197-1.2	T363I	Pathogenic	0.978
LRP5	O75197-1.2	T363K	Pathogenic	0.983
LRP5	O75197-1.2	T363L	Pathogenic	0.98
LRP5	O75197-1.2	T363M	Pathogenic	0.987
LRP5	O75197-1.2	T363N	Pathogenic	0.966
LRP5	O75197-1.2	T363P	Pathogenic	0.992
LRP5	O75197-1.2	T363Q	Pathogenic	0.992
LRP5	O75197-1.2	T363R	Pathogenic	0.982
LRP5	O75197-1.2	T363S	Pathogenic	0.937
LRP5	O75197-1.2	T363V	Pathogenic	0.962
LRP5	O75197-1.2	T363W	Pathogenic	0.988
LRP5	O75197-1.2	T363Y	Pathogenic	0.996
LRP5	O75197-1.2	D364A	Pathogenic	0.978
LRP5	O75197-1.2	D364C	Pathogenic	0.987
LRP5	O75197-1.2	D364E	Pathogenic	0.548
LRP5	O75197-1.2	D364F	Pathogenic	0.972
LRP5	O75197-1.2	D364G	Pathogenic	0.949
LRP5	O75197-1.2	D364H	Pathogenic	0.944
LRP5	O75197-1.2	D364I	Pathogenic	0.972
LRP5	O75197-1.2	D364K	Pathogenic	0.968
LRP5	O75197-1.2	D364L	Pathogenic	0.991
LRP5	O75197-1.2	D364M	Pathogenic	0.983
LRP5	O75197-1.2	D364N	Pathogenic	0.785
LRP5	O75197-1.2	D364P	Pathogenic	0.913
LRP5	O75197-1.2	D364Q	Pathogenic	0.885
LRP5	O75197-1.2	D364R	Pathogenic	0.989
LRP5	O75197-1.2	D364S	Pathogenic	0.868
LRP5	O75197-1.2	D364T	Pathogenic	0.94
LRP5	O75197-1.2	D364V	Pathogenic	0.984
LRP5	O75197-1.2	D364W	Pathogenic	0.985
LRP5	O75197-1.2	D364Y	Pathogenic	0.986
LRP5	O75197-1.2	I365A	Pathogenic	0.709
LRP5	O75197-1.2	I365C	Pathogenic	0.821
LRP5	O75197-1.2	I365D	Pathogenic	0.899
LRP5	O75197-1.2	I365E	Pathogenic	0.912
LRP5	O75197-1.2	I365F	Pathogenic	0.764
LRP5	O75197-1.2	I365G	Pathogenic	0.981
LRP5	O75197-1.2	I365H	Pathogenic	0.954
LRP5	O75197-1.2	I365K	Pathogenic	0.884
LRP5	O75197-1.2	I365L	Neutral	0.247
LRP5	O75197-1.2	I365M	Neutral	0.397
LRP5	O75197-1.2	I365N	Pathogenic	0.913
LRP5	O75197-1.2	I365P	Pathogenic	0.971
LRP5	O75197-1.2	I365Q	Pathogenic	0.938
LRP5	O75197-1.2	I365R	Pathogenic	0.88
LRP5	O75197-1.2	I365S	Pathogenic	0.846
LRP5	O75197-1.2	I365T	Pathogenic	0.708
LRP5	O75197-1.2	I365V	Neutral	0.064
LRP5	O75197-1.2	I365W	Pathogenic	0.983
LRP5	O75197-1.2	I365Y	Pathogenic	0.823
LRP5	O75197-1.2	V366A	Pathogenic	0.682
LRP5	O75197-1.2	V366C	Pathogenic	0.925
LRP5	O75197-1.2	V366D	Pathogenic	0.96
LRP5	O75197-1.2	V366E	Pathogenic	0.9
LRP5	O75197-1.2	V366F	Pathogenic	0.9
LRP5	O75197-1.2	V366G	Pathogenic	0.978
LRP5	O75197-1.2	V366H	Pathogenic	0.982
LRP5	O75197-1.2	V366I	Neutral	0.095
LRP5	O75197-1.2	V366K	Pathogenic	0.863
LRP5	O75197-1.2	V366L	Pathogenic	0.516
LRP5	O75197-1.2	V366M	Pathogenic	0.618
LRP5	O75197-1.2	V366N	Pathogenic	0.966
LRP5	O75197-1.2	V366P	Pathogenic	0.968
LRP5	O75197-1.2	V366Q	Pathogenic	0.929
LRP5	O75197-1.2	V366R	Pathogenic	0.949
LRP5	O75197-1.2	V366S	Pathogenic	0.937
LRP5	O75197-1.2	V366T	Pathogenic	0.682
LRP5	O75197-1.2	V366W	Pathogenic	0.981
LRP5	O75197-1.2	V366Y	Pathogenic	0.922
LRP5	O75197-1.2	L367A	Pathogenic	0.966
LRP5	O75197-1.2	L367C	Pathogenic	0.982
LRP5	O75197-1.2	L367D	Pathogenic	0.997
LRP5	O75197-1.2	L367E	Pathogenic	0.992
LRP5	O75197-1.2	L367F	Pathogenic	0.97
LRP5	O75197-1.2	L367G	Pathogenic	0.998
LRP5	O75197-1.2	L367H	Pathogenic	0.996
LRP5	O75197-1.2	L367I	Pathogenic	0.777
LRP5	O75197-1.2	L367K	Pathogenic	0.967
LRP5	O75197-1.2	L367M	Pathogenic	0.716
LRP5	O75197-1.2	L367N	Pathogenic	0.992
LRP5	O75197-1.2	L367P	Pathogenic	0.997
LRP5	O75197-1.2	L367Q	Pathogenic	0.983
LRP5	O75197-1.2	L367R	Pathogenic	0.966
LRP5	O75197-1.2	L367S	Pathogenic	0.985
LRP5	O75197-1.2	L367T	Pathogenic	0.966
LRP5	O75197-1.2	L367V	Pathogenic	0.88
LRP5	O75197-1.2	L367W	Pathogenic	0.995
LRP5	O75197-1.2	L367Y	Pathogenic	0.982
LRP5	O75197-1.2	Q368A	Pathogenic	0.874
LRP5	O75197-1.2	Q368C	Pathogenic	0.973
LRP5	O75197-1.2	Q368D	Pathogenic	0.698
LRP5	O75197-1.2	Q368E	Neutral	0.225
LRP5	O75197-1.2	Q368F	Pathogenic	0.947
LRP5	O75197-1.2	Q368G	Pathogenic	0.964
LRP5	O75197-1.2	Q368H	Pathogenic	0.74
LRP5	O75197-1.2	Q368I	Pathogenic	0.947
LRP5	O75197-1.2	Q368K	Neutral	0.385
LRP5	O75197-1.2	Q368L	Pathogenic	0.865
LRP5	O75197-1.2	Q368M	Pathogenic	0.514
LRP5	O75197-1.2	Q368N	Pathogenic	0.731
LRP5	O75197-1.2	Q368P	Pathogenic	0.832
LRP5	O75197-1.2	Q368R	Neutral	0.377
LRP5	O75197-1.2	Q368S	Pathogenic	0.757
LRP5	O75197-1.2	Q368T	Pathogenic	0.883
LRP5	O75197-1.2	Q368V	Pathogenic	0.908
LRP5	O75197-1.2	Q368W	Pathogenic	0.787
LRP5	O75197-1.2	Q368Y	Pathogenic	0.799
LRP5	O75197-1.2	V369A	Neutral	0.081
LRP5	O75197-1.2	V369C	Neutral	0.337
LRP5	O75197-1.2	V369D	Neutral	0.497
LRP5	O75197-1.2	V369E	Neutral	0.271
LRP5	O75197-1.2	V369F	Neutral	0.27
LRP5	O75197-1.2	V369G	Pathogenic	0.647
LRP5	O75197-1.2	V369H	Pathogenic	0.689
LRP5	O75197-1.2	V369I	Neutral	0.004
LRP5	O75197-1.2	V369K	Neutral	0.206
LRP5	O75197-1.2	V369L	Neutral	0.042
LRP5	O75197-1.2	V369M	Neutral	0.063
LRP5	O75197-1.2	V369N	Pathogenic	0.537
LRP5	O75197-1.2	V369P	Pathogenic	0.551
LRP5	O75197-1.2	V369Q	Neutral	0.349
LRP5	O75197-1.2	V369R	Neutral	0.433
LRP5	O75197-1.2	V369S	Neutral	0.378
LRP5	O75197-1.2	V369T	Neutral	0.081
LRP5	O75197-1.2	V369W	Pathogenic	0.684
LRP5	O75197-1.2	V369Y	Neutral	0.326
LRP5	O75197-1.2	D370A	Neutral	0.261
LRP5	O75197-1.2	D370C	Neutral	0.377
LRP5	O75197-1.2	D370E	Neutral	0.01
LRP5	O75197-1.2	D370F	Neutral	0.217
LRP5	O75197-1.2	D370G	Neutral	0.129
LRP5	O75197-1.2	D370H	Neutral	0.119
LRP5	O75197-1.2	D370I	Neutral	0.217
LRP5	O75197-1.2	D370K	Neutral	0.195
LRP5	O75197-1.2	D370L	Neutral	0.481
LRP5	O75197-1.2	D370M	Neutral	0.317
LRP5	O75197-1.2	D370N	Neutral	0.028
LRP5	O75197-1.2	D370P	Neutral	0.077
LRP5	O75197-1.2	D370Q	Neutral	0.058
LRP5	O75197-1.2	D370R	Neutral	0.416
LRP5	O75197-1.2	D370S	Neutral	0.05
LRP5	O75197-1.2	D370T	Neutral	0.112
LRP5	O75197-1.2	D370V	Neutral	0.326
LRP5	O75197-1.2	D370W	Neutral	0.347
LRP5	O75197-1.2	D370Y	Neutral	0.365
LRP5	O75197-1.2	D371A	Pathogenic	0.766
LRP5	O75197-1.2	D371C	Pathogenic	0.849
LRP5	O75197-1.2	D371E	Neutral	0.082
LRP5	O75197-1.2	D371F	Pathogenic	0.719
LRP5	O75197-1.2	D371G	Pathogenic	0.579
LRP5	O75197-1.2	D371H	Pathogenic	0.556
LRP5	O75197-1.2	D371I	Pathogenic	0.72
LRP5	O75197-1.2	D371K	Pathogenic	0.692
LRP5	O75197-1.2	D371L	Pathogenic	0.896
LRP5	O75197-1.2	D371M	Pathogenic	0.811
LRP5	O75197-1.2	D371N	Neutral	0.213
LRP5	O75197-1.2	D371P	Neutral	0.436
LRP5	O75197-1.2	D371Q	Neutral	0.362
LRP5	O75197-1.2	D371R	Pathogenic	0.868
LRP5	O75197-1.2	D371S	Neutral	0.327
LRP5	O75197-1.2	D371T	Pathogenic	0.538
LRP5	O75197-1.2	D371V	Pathogenic	0.818
LRP5	O75197-1.2	D371W	Pathogenic	0.831
LRP5	O75197-1.2	D371Y	Pathogenic	0.842
LRP5	O75197-1.2	I372A	Pathogenic	0.948
LRP5	O75197-1.2	I372C	Pathogenic	0.972
LRP5	O75197-1.2	I372D	Pathogenic	0.985
LRP5	O75197-1.2	I372E	Pathogenic	0.987
LRP5	O75197-1.2	I372F	Pathogenic	0.96
LRP5	O75197-1.2	I372G	Pathogenic	0.997
LRP5	O75197-1.2	I372H	Pathogenic	0.994
LRP5	O75197-1.2	I372K	Pathogenic	0.983
LRP5	O75197-1.2	I372L	Pathogenic	0.71
LRP5	O75197-1.2	I372M	Pathogenic	0.83
LRP5	O75197-1.2	I372N	Pathogenic	0.987
LRP5	O75197-1.2	I372P	Pathogenic	0.996
LRP5	O75197-1.2	I372Q	Pathogenic	0.991
LRP5	O75197-1.2	I372R	Pathogenic	0.982
LRP5	O75197-1.2	I372S	Pathogenic	0.976
LRP5	O75197-1.2	I372T	Pathogenic	0.947
LRP5	O75197-1.2	I372V	Neutral	0.336
LRP5	O75197-1.2	I372W	Pathogenic	0.998
LRP5	O75197-1.2	I372Y	Pathogenic	0.972
LRP5	O75197-1.2	R373A	Pathogenic	0.845
LRP5	O75197-1.2	R373C	Pathogenic	0.966
LRP5	O75197-1.2	R373D	Pathogenic	0.978
LRP5	O75197-1.2	R373E	Pathogenic	0.817
LRP5	O75197-1.2	R373F	Pathogenic	0.937
LRP5	O75197-1.2	R373G	Pathogenic	0.955
LRP5	O75197-1.2	R373H	Pathogenic	0.694
LRP5	O75197-1.2	R373I	Pathogenic	0.935
LRP5	O75197-1.2	R373K	Neutral	0.407
LRP5	O75197-1.2	R373L	Pathogenic	0.839
LRP5	O75197-1.2	R373M	Pathogenic	0.723
LRP5	O75197-1.2	R373N	Pathogenic	0.808
LRP5	O75197-1.2	R373P	Pathogenic	0.922
LRP5	O75197-1.2	R373Q	Pathogenic	0.504
LRP5	O75197-1.2	R373S	Pathogenic	0.882
LRP5	O75197-1.2	R373T	Pathogenic	0.856
LRP5	O75197-1.2	R373V	Pathogenic	0.96
LRP5	O75197-1.2	R373W	Pathogenic	0.908
LRP5	O75197-1.2	R373Y	Pathogenic	0.912
LRP5	O75197-1.2	H374A	Pathogenic	0.999
LRP5	O75197-1.2	H374C	Pathogenic	1.0
LRP5	O75197-1.2	H374D	Pathogenic	0.996
LRP5	O75197-1.2	H374E	Pathogenic	0.989
LRP5	O75197-1.2	H374F	Pathogenic	0.992
LRP5	O75197-1.2	H374G	Pathogenic	0.999
LRP5	O75197-1.2	H374I	Pathogenic	0.999
LRP5	O75197-1.2	H374K	Pathogenic	0.995
LRP5	O75197-1.2	H374L	Pathogenic	0.999
LRP5	O75197-1.2	H374M	Pathogenic	0.998
LRP5	O75197-1.2	H374N	Pathogenic	0.967
LRP5	O75197-1.2	H374P	Pathogenic	0.999
LRP5	O75197-1.2	H374Q	Pathogenic	0.992
LRP5	O75197-1.2	H374R	Pathogenic	0.984
LRP5	O75197-1.2	H374S	Pathogenic	0.998
LRP5	O75197-1.2	H374T	Pathogenic	0.999
LRP5	O75197-1.2	H374V	Pathogenic	0.999
LRP5	O75197-1.2	H374W	Pathogenic	0.996
LRP5	O75197-1.2	H374Y	Pathogenic	0.898
LRP5	O75197-1.2	A375C	Pathogenic	0.956
LRP5	O75197-1.2	A375D	Pathogenic	0.993
LRP5	O75197-1.2	A375E	Pathogenic	0.98
LRP5	O75197-1.2	A375F	Pathogenic	0.989
LRP5	O75197-1.2	A375G	Pathogenic	0.968
LRP5	O75197-1.2	A375H	Pathogenic	0.997
LRP5	O75197-1.2	A375I	Pathogenic	0.968
LRP5	O75197-1.2	A375K	Pathogenic	0.972
LRP5	O75197-1.2	A375L	Pathogenic	0.97
LRP5	O75197-1.2	A375M	Pathogenic	0.98
LRP5	O75197-1.2	A375N	Pathogenic	0.994
LRP5	O75197-1.2	A375P	Pathogenic	0.988
LRP5	O75197-1.2	A375Q	Pathogenic	0.986
LRP5	O75197-1.2	A375R	Pathogenic	0.971
LRP5	O75197-1.2	A375S	Pathogenic	0.908
LRP5	O75197-1.2	A375T	Pathogenic	0.974
LRP5	O75197-1.2	A375V	Pathogenic	0.945
LRP5	O75197-1.2	A375W	Pathogenic	0.994
LRP5	O75197-1.2	A375Y	Pathogenic	0.995
LRP5	O75197-1.2	I376A	Pathogenic	0.978
LRP5	O75197-1.2	I376C	Pathogenic	0.988
LRP5	O75197-1.2	I376D	Pathogenic	0.994
LRP5	O75197-1.2	I376E	Pathogenic	0.995
LRP5	O75197-1.2	I376F	Pathogenic	0.983
LRP5	O75197-1.2	I376G	Pathogenic	0.999
LRP5	O75197-1.2	I376H	Pathogenic	0.997
LRP5	O75197-1.2	I376K	Pathogenic	0.993
LRP5	O75197-1.2	I376L	Pathogenic	0.855
LRP5	O75197-1.2	I376M	Pathogenic	0.922
LRP5	O75197-1.2	I376N	Pathogenic	0.995
LRP5	O75197-1.2	I376P	Pathogenic	0.998
LRP5	O75197-1.2	I376Q	Pathogenic	0.996
LRP5	O75197-1.2	I376R	Pathogenic	0.992
LRP5	O75197-1.2	I376S	Pathogenic	0.99
LRP5	O75197-1.2	I376T	Pathogenic	0.977
LRP5	O75197-1.2	I376V	Pathogenic	0.549
LRP5	O75197-1.2	I376W	Pathogenic	0.999
LRP5	O75197-1.2	I376Y	Pathogenic	0.988
LRP5	O75197-1.2	A377C	Pathogenic	0.978
LRP5	O75197-1.2	A377D	Pathogenic	0.997
LRP5	O75197-1.2	A377E	Pathogenic	0.99
LRP5	O75197-1.2	A377F	Pathogenic	0.995
LRP5	O75197-1.2	A377G	Pathogenic	0.984
LRP5	O75197-1.2	A377H	Pathogenic	0.998
LRP5	O75197-1.2	A377I	Pathogenic	0.984
LRP5	O75197-1.2	A377K	Pathogenic	0.986
LRP5	O75197-1.2	A377L	Pathogenic	0.985
LRP5	O75197-1.2	A377M	Pathogenic	0.99
LRP5	O75197-1.2	A377N	Pathogenic	0.997
LRP5	O75197-1.2	A377P	Pathogenic	0.994
LRP5	O75197-1.2	A377Q	Pathogenic	0.993
LRP5	O75197-1.2	A377R	Pathogenic	0.986
LRP5	O75197-1.2	A377S	Pathogenic	0.953
LRP5	O75197-1.2	A377T	Pathogenic	0.987
LRP5	O75197-1.2	A377V	Pathogenic	0.972
LRP5	O75197-1.2	A377W	Pathogenic	0.997
LRP5	O75197-1.2	A377Y	Pathogenic	0.997
LRP5	O75197-1.2	I378A	Pathogenic	0.914
LRP5	O75197-1.2	I378C	Pathogenic	0.953
LRP5	O75197-1.2	I378D	Pathogenic	0.975
LRP5	O75197-1.2	I378E	Pathogenic	0.978
LRP5	O75197-1.2	I378F	Pathogenic	0.934
LRP5	O75197-1.2	I378G	Pathogenic	0.995
LRP5	O75197-1.2	I378H	Pathogenic	0.989
LRP5	O75197-1.2	I378K	Pathogenic	0.971
LRP5	O75197-1.2	I378L	Pathogenic	0.59
LRP5	O75197-1.2	I378M	Pathogenic	0.742
LRP5	O75197-1.2	I378N	Pathogenic	0.979
LRP5	O75197-1.2	I378P	Pathogenic	0.993
LRP5	O75197-1.2	I378Q	Pathogenic	0.985
LRP5	O75197-1.2	I378R	Pathogenic	0.97
LRP5	O75197-1.2	I378S	Pathogenic	0.96
LRP5	O75197-1.2	I378T	Pathogenic	0.914
LRP5	O75197-1.2	I378V	Neutral	0.23
LRP5	O75197-1.2	I378W	Pathogenic	0.996
LRP5	O75197-1.2	I378Y	Pathogenic	0.953
LRP5	O75197-1.2	D379A	Pathogenic	0.992
LRP5	O75197-1.2	D379C	Pathogenic	0.995
LRP5	O75197-1.2	D379E	Pathogenic	0.775
LRP5	O75197-1.2	D379F	Pathogenic	0.99
LRP5	O75197-1.2	D379G	Pathogenic	0.981
LRP5	O75197-1.2	D379H	Pathogenic	0.98
LRP5	O75197-1.2	D379I	Pathogenic	0.99
LRP5	O75197-1.2	D379K	Pathogenic	0.988
LRP5	O75197-1.2	D379L	Pathogenic	0.997
LRP5	O75197-1.2	D379M	Pathogenic	0.994
LRP5	O75197-1.2	D379N	Pathogenic	0.912
LRP5	O75197-1.2	D379P	Pathogenic	0.967
LRP5	O75197-1.2	D379Q	Pathogenic	0.956
LRP5	O75197-1.2	D379R	Pathogenic	0.996
LRP5	O75197-1.2	D379S	Pathogenic	0.949
LRP5	O75197-1.2	D379T	Pathogenic	0.978
LRP5	O75197-1.2	D379V	Pathogenic	0.994
LRP5	O75197-1.2	D379W	Pathogenic	0.995
LRP5	O75197-1.2	D379Y	Pathogenic	0.995
LRP5	O75197-1.2	Y380A	Pathogenic	0.979
LRP5	O75197-1.2	Y380C	Pathogenic	0.988
LRP5	O75197-1.2	Y380D	Pathogenic	0.983
LRP5	O75197-1.2	Y380E	Pathogenic	0.956
LRP5	O75197-1.2	Y380F	Neutral	0.146
LRP5	O75197-1.2	Y380G	Pathogenic	0.991
LRP5	O75197-1.2	Y380H	Neutral	0.337
LRP5	O75197-1.2	Y380I	Pathogenic	0.934
LRP5	O75197-1.2	Y380K	Pathogenic	0.943
LRP5	O75197-1.2	Y380L	Pathogenic	0.94
LRP5	O75197-1.2	Y380M	Pathogenic	0.96
LRP5	O75197-1.2	Y380N	Pathogenic	0.956
LRP5	O75197-1.2	Y380P	Pathogenic	0.995
LRP5	O75197-1.2	Y380Q	Pathogenic	0.912
LRP5	O75197-1.2	Y380R	Pathogenic	0.942
LRP5	O75197-1.2	Y380S	Pathogenic	0.972
LRP5	O75197-1.2	Y380T	Pathogenic	0.979
LRP5	O75197-1.2	Y380V	Pathogenic	0.959
LRP5	O75197-1.2	Y380W	Neutral	0.252
LRP5	O75197-1.2	D381A	Pathogenic	0.991
LRP5	O75197-1.2	D381C	Pathogenic	0.995
LRP5	O75197-1.2	D381E	Pathogenic	0.759
LRP5	O75197-1.2	D381F	Pathogenic	0.989
LRP5	O75197-1.2	D381G	Pathogenic	0.98
LRP5	O75197-1.2	D381H	Pathogenic	0.978
LRP5	O75197-1.2	D381I	Pathogenic	0.989
LRP5	O75197-1.2	D381K	Pathogenic	0.987
LRP5	O75197-1.2	D381L	Pathogenic	0.997
LRP5	O75197-1.2	D381M	Pathogenic	0.993
LRP5	O75197-1.2	D381N	Pathogenic	0.904
LRP5	O75197-1.2	D381P	Pathogenic	0.964
LRP5	O75197-1.2	D381Q	Pathogenic	0.952
LRP5	O75197-1.2	D381R	Pathogenic	0.996
LRP5	O75197-1.2	D381S	Pathogenic	0.944
LRP5	O75197-1.2	D381T	Pathogenic	0.976
LRP5	O75197-1.2	D381V	Pathogenic	0.994
LRP5	O75197-1.2	D381W	Pathogenic	0.994
LRP5	O75197-1.2	D381Y	Pathogenic	0.995
LRP5	O75197-1.2	P382A	Pathogenic	0.98
LRP5	O75197-1.2	P382C	Pathogenic	0.998
LRP5	O75197-1.2	P382D	Pathogenic	0.952
LRP5	O75197-1.2	P382E	Pathogenic	0.956
LRP5	O75197-1.2	P382F	Pathogenic	0.999
LRP5	O75197-1.2	P382G	Pathogenic	0.991
LRP5	O75197-1.2	P382H	Pathogenic	0.992
LRP5	O75197-1.2	P382I	Pathogenic	0.996
LRP5	O75197-1.2	P382K	Pathogenic	0.938
LRP5	O75197-1.2	P382L	Pathogenic	0.996
LRP5	O75197-1.2	P382M	Pathogenic	0.993
LRP5	O75197-1.2	P382N	Pathogenic	0.986
LRP5	O75197-1.2	P382Q	Pathogenic	0.969
LRP5	O75197-1.2	P382R	Pathogenic	0.978
LRP5	O75197-1.2	P382S	Pathogenic	0.974
LRP5	O75197-1.2	P382T	Pathogenic	0.98
LRP5	O75197-1.2	P382V	Pathogenic	0.993
LRP5	O75197-1.2	P382W	Pathogenic	0.998
LRP5	O75197-1.2	P382Y	Pathogenic	0.998
LRP5	O75197-1.2	L383A	Neutral	0.182
LRP5	O75197-1.2	L383C	Neutral	0.295
LRP5	O75197-1.2	L383D	Pathogenic	0.713
LRP5	O75197-1.2	L383E	Neutral	0.486
LRP5	O75197-1.2	L383F	Neutral	0.202
LRP5	O75197-1.2	L383G	Pathogenic	0.822
LRP5	O75197-1.2	L383H	Pathogenic	0.656
LRP5	O75197-1.2	L383I	Neutral	0.027
LRP5	O75197-1.2	L383K	Neutral	0.186
LRP5	O75197-1.2	L383M	Neutral	0.019
LRP5	O75197-1.2	L383N	Neutral	0.489
LRP5	O75197-1.2	L383P	Pathogenic	0.755
LRP5	O75197-1.2	L383Q	Neutral	0.313
LRP5	O75197-1.2	L383R	Neutral	0.181
LRP5	O75197-1.2	L383S	Neutral	0.334
LRP5	O75197-1.2	L383T	Neutral	0.181
LRP5	O75197-1.2	L383V	Neutral	0.054
LRP5	O75197-1.2	L383W	Pathogenic	0.597
LRP5	O75197-1.2	L383Y	Neutral	0.298
LRP5	O75197-1.2	E384A	Pathogenic	0.82
LRP5	O75197-1.2	E384C	Pathogenic	0.986
LRP5	O75197-1.2	E384D	Neutral	0.258
LRP5	O75197-1.2	E384F	Pathogenic	0.92
LRP5	O75197-1.2	E384G	Pathogenic	0.946
LRP5	O75197-1.2	E384H	Pathogenic	0.648
LRP5	O75197-1.2	E384I	Pathogenic	0.92
LRP5	O75197-1.2	E384K	Neutral	0.461
LRP5	O75197-1.2	E384L	Pathogenic	0.927
LRP5	O75197-1.2	E384M	Pathogenic	0.863
LRP5	O75197-1.2	E384N	Pathogenic	0.779
LRP5	O75197-1.2	E384P	Pathogenic	0.766
LRP5	O75197-1.2	E384Q	Neutral	0.215
LRP5	O75197-1.2	E384R	Pathogenic	0.716
LRP5	O75197-1.2	E384S	Pathogenic	0.672
LRP5	O75197-1.2	E384T	Pathogenic	0.832
LRP5	O75197-1.2	E384V	Pathogenic	0.867
LRP5	O75197-1.2	E384W	Pathogenic	0.879
LRP5	O75197-1.2	E384Y	Pathogenic	0.887
LRP5	O75197-1.2	G385A	Pathogenic	0.866
LRP5	O75197-1.2	G385C	Pathogenic	0.99
LRP5	O75197-1.2	G385D	Pathogenic	0.926
LRP5	O75197-1.2	G385E	Pathogenic	0.977
LRP5	O75197-1.2	G385F	Pathogenic	0.978
LRP5	O75197-1.2	G385H	Pathogenic	0.985
LRP5	O75197-1.2	G385I	Pathogenic	0.993
LRP5	O75197-1.2	G385K	Pathogenic	0.967
LRP5	O75197-1.2	G385L	Pathogenic	0.993
LRP5	O75197-1.2	G385M	Pathogenic	0.986
LRP5	O75197-1.2	G385N	Pathogenic	0.826
LRP5	O75197-1.2	G385P	Pathogenic	0.976
LRP5	O75197-1.2	G385Q	Pathogenic	0.984
LRP5	O75197-1.2	G385R	Pathogenic	0.966
LRP5	O75197-1.2	G385S	Pathogenic	0.891
LRP5	O75197-1.2	G385T	Pathogenic	0.984
LRP5	O75197-1.2	G385V	Pathogenic	0.987
LRP5	O75197-1.2	G385W	Pathogenic	0.9
LRP5	O75197-1.2	G385Y	Pathogenic	0.989
LRP5	O75197-1.2	Y386A	Pathogenic	0.945
LRP5	O75197-1.2	Y386C	Pathogenic	0.969
LRP5	O75197-1.2	Y386D	Pathogenic	0.954
LRP5	O75197-1.2	Y386E	Pathogenic	0.887
LRP5	O75197-1.2	Y386F	Neutral	0.059
LRP5	O75197-1.2	Y386G	Pathogenic	0.975
LRP5	O75197-1.2	Y386H	Neutral	0.156
LRP5	O75197-1.2	Y386I	Pathogenic	0.838
LRP5	O75197-1.2	Y386K	Pathogenic	0.857
LRP5	O75197-1.2	Y386L	Pathogenic	0.85
LRP5	O75197-1.2	Y386M	Pathogenic	0.896
LRP5	O75197-1.2	Y386N	Pathogenic	0.888
LRP5	O75197-1.2	Y386P	Pathogenic	0.987
LRP5	O75197-1.2	Y386Q	Pathogenic	0.791
LRP5	O75197-1.2	Y386R	Pathogenic	0.855
LRP5	O75197-1.2	Y386S	Pathogenic	0.927
LRP5	O75197-1.2	Y386T	Pathogenic	0.944
LRP5	O75197-1.2	Y386V	Pathogenic	0.895
LRP5	O75197-1.2	Y386W	Neutral	0.109
LRP5	O75197-1.2	V387A	Neutral	0.12
LRP5	O75197-1.2	V387C	Neutral	0.439
LRP5	O75197-1.2	V387D	Pathogenic	0.603
LRP5	O75197-1.2	V387E	Neutral	0.364
LRP5	O75197-1.2	V387F	Neutral	0.362
LRP5	O75197-1.2	V387G	Pathogenic	0.739
LRP5	O75197-1.2	V387H	Pathogenic	0.773
LRP5	O75197-1.2	V387I	Neutral	0.007
LRP5	O75197-1.2	V387K	Neutral	0.286
LRP5	O75197-1.2	V387L	Neutral	0.063
LRP5	O75197-1.2	V387M	Neutral	0.093
LRP5	O75197-1.2	V387N	Pathogenic	0.641
LRP5	O75197-1.2	V387P	Pathogenic	0.654
LRP5	O75197-1.2	V387Q	Neutral	0.452
LRP5	O75197-1.2	V387R	Pathogenic	0.541
LRP5	O75197-1.2	V387S	Neutral	0.483
LRP5	O75197-1.2	V387T	Neutral	0.12
LRP5	O75197-1.2	V387W	Pathogenic	0.769
LRP5	O75197-1.2	V387Y	Neutral	0.427
LRP5	O75197-1.2	Y388A	Pathogenic	0.998
LRP5	O75197-1.2	Y388C	Pathogenic	0.999
LRP5	O75197-1.2	Y388D	Pathogenic	0.998
LRP5	O75197-1.2	Y388E	Pathogenic	0.996
LRP5	O75197-1.2	Y388F	Pathogenic	0.654
LRP5	O75197-1.2	Y388G	Pathogenic	0.999
LRP5	O75197-1.2	Y388H	Pathogenic	0.848
LRP5	O75197-1.2	Y388I	Pathogenic	0.994
LRP5	O75197-1.2	Y388K	Pathogenic	0.994
LRP5	O75197-1.2	Y388L	Pathogenic	0.994
LRP5	O75197-1.2	Y388M	Pathogenic	0.996
LRP5	O75197-1.2	Y388N	Pathogenic	0.996
LRP5	O75197-1.2	Y388P	Pathogenic	1.0
LRP5	O75197-1.2	Y388Q	Pathogenic	0.991
LRP5	O75197-1.2	Y388R	Pathogenic	0.994
LRP5	O75197-1.2	Y388S	Pathogenic	0.997
LRP5	O75197-1.2	Y388T	Pathogenic	0.998
LRP5	O75197-1.2	Y388V	Pathogenic	0.996
LRP5	O75197-1.2	Y388W	Pathogenic	0.787
LRP5	O75197-1.2	W389A	Pathogenic	0.999
LRP5	O75197-1.2	W389C	Pathogenic	0.998
LRP5	O75197-1.2	W389D	Pathogenic	0.999
LRP5	O75197-1.2	W389E	Pathogenic	0.998
LRP5	O75197-1.2	W389F	Pathogenic	0.978
LRP5	O75197-1.2	W389G	Pathogenic	0.995
LRP5	O75197-1.2	W389H	Pathogenic	0.996
LRP5	O75197-1.2	W389I	Pathogenic	1.0
LRP5	O75197-1.2	W389K	Pathogenic	0.997
LRP5	O75197-1.2	W389L	Pathogenic	0.999
LRP5	O75197-1.2	W389M	Pathogenic	0.996
LRP5	O75197-1.2	W389N	Pathogenic	0.999
LRP5	O75197-1.2	W389P	Pathogenic	1.0
LRP5	O75197-1.2	W389Q	Pathogenic	0.995
LRP5	O75197-1.2	W389R	Pathogenic	0.997
LRP5	O75197-1.2	W389S	Pathogenic	0.999
LRP5	O75197-1.2	W389T	Pathogenic	0.997
LRP5	O75197-1.2	W389V	Pathogenic	1.0
LRP5	O75197-1.2	W389Y	Pathogenic	0.875
LRP5	O75197-1.2	T390A	Pathogenic	0.959
LRP5	O75197-1.2	T390C	Pathogenic	0.976
LRP5	O75197-1.2	T390D	Pathogenic	0.969
LRP5	O75197-1.2	T390E	Pathogenic	0.972
LRP5	O75197-1.2	T390F	Pathogenic	0.983
LRP5	O75197-1.2	T390G	Pathogenic	0.994
LRP5	O75197-1.2	T390H	Pathogenic	0.995
LRP5	O75197-1.2	T390I	Pathogenic	0.949
LRP5	O75197-1.2	T390K	Pathogenic	0.96
LRP5	O75197-1.2	T390L	Pathogenic	0.953
LRP5	O75197-1.2	T390M	Pathogenic	0.969
LRP5	O75197-1.2	T390N	Pathogenic	0.922
LRP5	O75197-1.2	T390P	Pathogenic	0.981
LRP5	O75197-1.2	T390Q	Pathogenic	0.98
LRP5	O75197-1.2	T390R	Pathogenic	0.959
LRP5	O75197-1.2	T390S	Pathogenic	0.863
LRP5	O75197-1.2	T390V	Pathogenic	0.914
LRP5	O75197-1.2	T390W	Pathogenic	0.973
LRP5	O75197-1.2	T390Y	Pathogenic	0.992
LRP5	O75197-1.2	D391A	Pathogenic	0.993
LRP5	O75197-1.2	D391C	Pathogenic	0.996
LRP5	O75197-1.2	D391E	Pathogenic	0.797
LRP5	O75197-1.2	D391F	Pathogenic	0.991
LRP5	O75197-1.2	D391G	Pathogenic	0.984
LRP5	O75197-1.2	D391H	Pathogenic	0.982
LRP5	O75197-1.2	D391I	Pathogenic	0.991
LRP5	O75197-1.2	D391K	Pathogenic	0.99
LRP5	O75197-1.2	D391L	Pathogenic	0.997
LRP5	O75197-1.2	D391M	Pathogenic	0.995
LRP5	O75197-1.2	D391N	Pathogenic	0.922
LRP5	O75197-1.2	D391P	Pathogenic	0.971
LRP5	O75197-1.2	D391Q	Pathogenic	0.961
LRP5	O75197-1.2	D391R	Pathogenic	0.997
LRP5	O75197-1.2	D391S	Pathogenic	0.955
LRP5	O75197-1.2	D391T	Pathogenic	0.981
LRP5	O75197-1.2	D391V	Pathogenic	0.995
LRP5	O75197-1.2	D391W	Pathogenic	0.995
LRP5	O75197-1.2	D391Y	Pathogenic	0.996
LRP5	O75197-1.2	D392A	Pathogenic	0.977
LRP5	O75197-1.2	D392C	Pathogenic	0.986
LRP5	O75197-1.2	D392E	Pathogenic	0.538
LRP5	O75197-1.2	D392F	Pathogenic	0.971
LRP5	O75197-1.2	D392G	Pathogenic	0.947
LRP5	O75197-1.2	D392H	Pathogenic	0.942
LRP5	O75197-1.2	D392I	Pathogenic	0.971
LRP5	O75197-1.2	D392K	Pathogenic	0.967
LRP5	O75197-1.2	D392L	Pathogenic	0.991
LRP5	O75197-1.2	D392M	Pathogenic	0.982
LRP5	O75197-1.2	D392N	Pathogenic	0.778
LRP5	O75197-1.2	D392P	Pathogenic	0.909
LRP5	O75197-1.2	D392Q	Pathogenic	0.88
LRP5	O75197-1.2	D392R	Pathogenic	0.988
LRP5	O75197-1.2	D392S	Pathogenic	0.863
LRP5	O75197-1.2	D392T	Pathogenic	0.938
LRP5	O75197-1.2	D392V	Pathogenic	0.983
LRP5	O75197-1.2	D392W	Pathogenic	0.985
LRP5	O75197-1.2	D392Y	Pathogenic	0.986
LRP5	O75197-1.2	E393A	Pathogenic	0.767
LRP5	O75197-1.2	E393C	Pathogenic	0.981
LRP5	O75197-1.2	E393D	Neutral	0.201
LRP5	O75197-1.2	E393F	Pathogenic	0.893
LRP5	O75197-1.2	E393G	Pathogenic	0.928
LRP5	O75197-1.2	E393H	Pathogenic	0.572
LRP5	O75197-1.2	E393I	Pathogenic	0.893
LRP5	O75197-1.2	E393K	Neutral	0.383
LRP5	O75197-1.2	E393L	Pathogenic	0.902
LRP5	O75197-1.2	E393M	Pathogenic	0.821
LRP5	O75197-1.2	E393N	Pathogenic	0.719
LRP5	O75197-1.2	E393P	Pathogenic	0.703
LRP5	O75197-1.2	E393Q	Neutral	0.166
LRP5	O75197-1.2	E393R	Pathogenic	0.646
LRP5	O75197-1.2	E393S	Pathogenic	0.598
LRP5	O75197-1.2	E393T	Pathogenic	0.782
LRP5	O75197-1.2	E393V	Pathogenic	0.825
LRP5	O75197-1.2	E393W	Pathogenic	0.84
LRP5	O75197-1.2	E393Y	Pathogenic	0.85
LRP5	O75197-1.2	V394A	Pathogenic	0.658
LRP5	O75197-1.2	V394C	Pathogenic	0.917
LRP5	O75197-1.2	V394D	Pathogenic	0.955
LRP5	O75197-1.2	V394E	Pathogenic	0.89
LRP5	O75197-1.2	V394F	Pathogenic	0.889
LRP5	O75197-1.2	V394G	Pathogenic	0.976
LRP5	O75197-1.2	V394H	Pathogenic	0.98
LRP5	O75197-1.2	V394I	Neutral	0.086
LRP5	O75197-1.2	V394K	Pathogenic	0.849
LRP5	O75197-1.2	V394L	Neutral	0.488
LRP5	O75197-1.2	V394M	Pathogenic	0.592
LRP5	O75197-1.2	V394N	Pathogenic	0.962
LRP5	O75197-1.2	V394P	Pathogenic	0.964
LRP5	O75197-1.2	V394Q	Pathogenic	0.921
LRP5	O75197-1.2	V394R	Pathogenic	0.943
LRP5	O75197-1.2	V394S	Pathogenic	0.93
LRP5	O75197-1.2	V394T	Pathogenic	0.657
LRP5	O75197-1.2	V394W	Pathogenic	0.979
LRP5	O75197-1.2	V394Y	Pathogenic	0.913
LRP5	O75197-1.2	R395A	Neutral	0.375
LRP5	O75197-1.2	R395C	Pathogenic	0.758
LRP5	O75197-1.2	R395D	Pathogenic	0.833
LRP5	O75197-1.2	R395E	Neutral	0.33
LRP5	O75197-1.2	R395F	Pathogenic	0.622
LRP5	O75197-1.2	R395G	Pathogenic	0.7
LRP5	O75197-1.2	R395H	Neutral	0.2
LRP5	O75197-1.2	R395I	Pathogenic	0.615
LRP5	O75197-1.2	R395K	Neutral	0.071
LRP5	O75197-1.2	R395L	Neutral	0.365
LRP5	O75197-1.2	R395M	Neutral	0.224
LRP5	O75197-1.2	R395N	Neutral	0.318
LRP5	O75197-1.2	R395P	Pathogenic	0.568
LRP5	O75197-1.2	R395Q	Neutral	0.101
LRP5	O75197-1.2	R395S	Neutral	0.452
LRP5	O75197-1.2	R395T	Neutral	0.396
LRP5	O75197-1.2	R395V	Pathogenic	0.724
LRP5	O75197-1.2	R395W	Pathogenic	0.521
LRP5	O75197-1.2	R395Y	Pathogenic	0.534
LRP5	O75197-1.2	A396C	Pathogenic	0.856
LRP5	O75197-1.2	A396D	Pathogenic	0.974
LRP5	O75197-1.2	A396E	Pathogenic	0.932
LRP5	O75197-1.2	A396F	Pathogenic	0.961
LRP5	O75197-1.2	A396G	Pathogenic	0.892
LRP5	O75197-1.2	A396H	Pathogenic	0.988
LRP5	O75197-1.2	A396I	Pathogenic	0.891
LRP5	O75197-1.2	A396K	Pathogenic	0.906
LRP5	O75197-1.2	A396L	Pathogenic	0.9
LRP5	O75197-1.2	A396M	Pathogenic	0.932
LRP5	O75197-1.2	A396N	Pathogenic	0.978
LRP5	O75197-1.2	A396P	Pathogenic	0.958
LRP5	O75197-1.2	A396Q	Pathogenic	0.952
LRP5	O75197-1.2	A396R	Pathogenic	0.903
LRP5	O75197-1.2	A396S	Pathogenic	0.729
LRP5	O75197-1.2	A396T	Pathogenic	0.911
LRP5	O75197-1.2	A396V	Pathogenic	0.824
LRP5	O75197-1.2	A396W	Pathogenic	0.979
LRP5	O75197-1.2	A396Y	Pathogenic	0.981
LRP5	O75197-1.2	I397A	Pathogenic	0.969
LRP5	O75197-1.2	I397C	Pathogenic	0.983
LRP5	O75197-1.2	I397D	Pathogenic	0.991
LRP5	O75197-1.2	I397E	Pathogenic	0.993
LRP5	O75197-1.2	I397F	Pathogenic	0.977
LRP5	O75197-1.2	I397G	Pathogenic	0.998
LRP5	O75197-1.2	I397H	Pathogenic	0.996
LRP5	O75197-1.2	I397K	Pathogenic	0.99
LRP5	O75197-1.2	I397L	Pathogenic	0.809
LRP5	O75197-1.2	I397M	Pathogenic	0.895
LRP5	O75197-1.2	I397N	Pathogenic	0.993
LRP5	O75197-1.2	I397P	Pathogenic	0.998
LRP5	O75197-1.2	I397Q	Pathogenic	0.995
LRP5	O75197-1.2	I397R	Pathogenic	0.99
LRP5	O75197-1.2	I397S	Pathogenic	0.986
LRP5	O75197-1.2	I397T	Pathogenic	0.969
LRP5	O75197-1.2	I397V	Neutral	0.467
LRP5	O75197-1.2	I397W	Pathogenic	0.999
LRP5	O75197-1.2	I397Y	Pathogenic	0.984
LRP5	O75197-1.2	R398A	Pathogenic	0.943
LRP5	O75197-1.2	R398C	Pathogenic	0.989
LRP5	O75197-1.2	R398D	Pathogenic	0.993
LRP5	O75197-1.2	R398E	Pathogenic	0.931
LRP5	O75197-1.2	R398F	Pathogenic	0.978
LRP5	O75197-1.2	R398G	Pathogenic	0.985
LRP5	O75197-1.2	R398H	Pathogenic	0.874
LRP5	O75197-1.2	R398I	Pathogenic	0.978
LRP5	O75197-1.2	R398K	Pathogenic	0.677
LRP5	O75197-1.2	R398L	Pathogenic	0.941
LRP5	O75197-1.2	R398M	Pathogenic	0.888
LRP5	O75197-1.2	R398N	Pathogenic	0.928
LRP5	O75197-1.2	R398P	Pathogenic	0.973
LRP5	O75197-1.2	R398Q	Pathogenic	0.756
LRP5	O75197-1.2	R398S	Pathogenic	0.958
LRP5	O75197-1.2	R398T	Pathogenic	0.948
LRP5	O75197-1.2	R398V	Pathogenic	0.986
LRP5	O75197-1.2	R398W	Pathogenic	0.968
LRP5	O75197-1.2	R398Y	Pathogenic	0.969
LRP5	O75197-1.2	R399A	Pathogenic	0.938
LRP5	O75197-1.2	R399C	Pathogenic	0.988
LRP5	O75197-1.2	R399D	Pathogenic	0.992
LRP5	O75197-1.2	R399E	Pathogenic	0.925
LRP5	O75197-1.2	R399F	Pathogenic	0.977
LRP5	O75197-1.2	R399G	Pathogenic	0.983
LRP5	O75197-1.2	R399H	Pathogenic	0.863
LRP5	O75197-1.2	R399I	Pathogenic	0.976
LRP5	O75197-1.2	R399K	Pathogenic	0.657
LRP5	O75197-1.2	R399L	Pathogenic	0.936
LRP5	O75197-1.2	R399M	Pathogenic	0.879
LRP5	O75197-1.2	R399N	Pathogenic	0.922
LRP5	O75197-1.2	R399P	Pathogenic	0.971
LRP5	O75197-1.2	R399Q	Pathogenic	0.739
LRP5	O75197-1.2	R399S	Pathogenic	0.954
LRP5	O75197-1.2	R399T	Pathogenic	0.943
LRP5	O75197-1.2	R399V	Pathogenic	0.985
LRP5	O75197-1.2	R399W	Pathogenic	0.965
LRP5	O75197-1.2	R399Y	Pathogenic	0.967
LRP5	O75197-1.2	A400C	Neutral	0.316
LRP5	O75197-1.2	A400D	Pathogenic	0.747
LRP5	O75197-1.2	A400E	Pathogenic	0.515
LRP5	O75197-1.2	A400F	Pathogenic	0.658
LRP5	O75197-1.2	A400G	Neutral	0.391
LRP5	O75197-1.2	A400H	Pathogenic	0.864
LRP5	O75197-1.2	A400I	Neutral	0.388
LRP5	O75197-1.2	A400K	Neutral	0.427
LRP5	O75197-1.2	A400L	Neutral	0.41
LRP5	O75197-1.2	A400M	Pathogenic	0.514
LRP5	O75197-1.2	A400N	Pathogenic	0.773
LRP5	O75197-1.2	A400P	Pathogenic	0.639
LRP5	O75197-1.2	A400Q	Pathogenic	0.605
LRP5	O75197-1.2	A400R	Neutral	0.419
LRP5	O75197-1.2	A400S	Neutral	0.173
LRP5	O75197-1.2	A400T	Neutral	0.444
LRP5	O75197-1.2	A400V	Neutral	0.267
LRP5	O75197-1.2	A400W	Pathogenic	0.787
LRP5	O75197-1.2	A400Y	Pathogenic	0.8
LRP5	O75197-1.2	Y401A	Neutral	0.081
LRP5	O75197-1.2	Y401C	Neutral	0.138
LRP5	O75197-1.2	Y401D	Neutral	0.096
LRP5	O75197-1.2	Y401E	Neutral	0.039
LRP5	O75197-1.2	Y401F	Neutral	0.0
LRP5	O75197-1.2	Y401G	Neutral	0.165
LRP5	O75197-1.2	Y401H	Neutral	0.001
LRP5	O75197-1.2	Y401I	Neutral	0.026
LRP5	O75197-1.2	Y401K	Neutral	0.03
LRP5	O75197-1.2	Y401L	Neutral	0.028
LRP5	O75197-1.2	Y401M	Neutral	0.043
LRP5	O75197-1.2	Y401N	Neutral	0.039
LRP5	O75197-1.2	Y401P	Neutral	0.286
LRP5	O75197-1.2	Y401Q	Neutral	0.019
LRP5	O75197-1.2	Y401R	Neutral	0.029
LRP5	O75197-1.2	Y401S	Neutral	0.061
LRP5	O75197-1.2	Y401T	Neutral	0.081
LRP5	O75197-1.2	Y401V	Neutral	0.042
LRP5	O75197-1.2	Y401W	Neutral	0.001
LRP5	O75197-1.2	L402A	Neutral	0.408
LRP5	O75197-1.2	L402C	Pathogenic	0.565
LRP5	O75197-1.2	L402D	Pathogenic	0.885
LRP5	O75197-1.2	L402E	Pathogenic	0.746
LRP5	O75197-1.2	L402F	Neutral	0.44
LRP5	O75197-1.2	L402G	Pathogenic	0.935
LRP5	O75197-1.2	L402H	Pathogenic	0.855
LRP5	O75197-1.2	L402I	Neutral	0.078
LRP5	O75197-1.2	L402K	Neutral	0.415
LRP5	O75197-1.2	L402M	Neutral	0.058
LRP5	O75197-1.2	L402N	Pathogenic	0.748
LRP5	O75197-1.2	L402P	Pathogenic	0.905
LRP5	O75197-1.2	L402Q	Pathogenic	0.585
LRP5	O75197-1.2	L402R	Neutral	0.406
LRP5	O75197-1.2	L402S	Pathogenic	0.609
LRP5	O75197-1.2	L402T	Neutral	0.407
LRP5	O75197-1.2	L402V	Neutral	0.152
LRP5	O75197-1.2	L402W	Pathogenic	0.821
LRP5	O75197-1.2	L402Y	Pathogenic	0.569
LRP5	O75197-1.2	D403A	Pathogenic	0.993
LRP5	O75197-1.2	D403C	Pathogenic	0.996
LRP5	O75197-1.2	D403E	Pathogenic	0.8
LRP5	O75197-1.2	D403F	Pathogenic	0.991
LRP5	O75197-1.2	D403G	Pathogenic	0.984
LRP5	O75197-1.2	D403H	Pathogenic	0.982
LRP5	O75197-1.2	D403I	Pathogenic	0.991
LRP5	O75197-1.2	D403K	Pathogenic	0.99
LRP5	O75197-1.2	D403L	Pathogenic	0.997
LRP5	O75197-1.2	D403M	Pathogenic	0.995
LRP5	O75197-1.2	D403N	Pathogenic	0.923
LRP5	O75197-1.2	D403P	Pathogenic	0.972
LRP5	O75197-1.2	D403Q	Pathogenic	0.962
LRP5	O75197-1.2	D403R	Pathogenic	0.997
LRP5	O75197-1.2	D403S	Pathogenic	0.956
LRP5	O75197-1.2	D403T	Pathogenic	0.981
LRP5	O75197-1.2	D403V	Pathogenic	0.995
LRP5	O75197-1.2	D403W	Pathogenic	0.995
LRP5	O75197-1.2	D403Y	Pathogenic	0.996
LRP5	O75197-1.2	G404A	Pathogenic	0.978
LRP5	O75197-1.2	G404C	Pathogenic	0.998
LRP5	O75197-1.2	G404D	Pathogenic	0.989
LRP5	O75197-1.2	G404E	Pathogenic	0.997
LRP5	O75197-1.2	G404F	Pathogenic	0.997
LRP5	O75197-1.2	G404H	Pathogenic	0.998
LRP5	O75197-1.2	G404I	Pathogenic	0.999
LRP5	O75197-1.2	G404K	Pathogenic	0.995
LRP5	O75197-1.2	G404L	Pathogenic	0.999
LRP5	O75197-1.2	G404M	Pathogenic	0.998
LRP5	O75197-1.2	G404N	Pathogenic	0.97
LRP5	O75197-1.2	G404P	Pathogenic	0.996
LRP5	O75197-1.2	G404Q	Pathogenic	0.998
LRP5	O75197-1.2	G404R	Pathogenic	0.995
LRP5	O75197-1.2	G404S	Pathogenic	0.982
LRP5	O75197-1.2	G404T	Pathogenic	0.998
LRP5	O75197-1.2	G404V	Pathogenic	0.998
LRP5	O75197-1.2	G404W	Pathogenic	0.984
LRP5	O75197-1.2	G404Y	Pathogenic	0.998
LRP5	O75197-1.2	S405A	Neutral	0.4
LRP5	O75197-1.2	S405C	Pathogenic	0.769
LRP5	O75197-1.2	S405D	Pathogenic	0.584
LRP5	O75197-1.2	S405E	Pathogenic	0.605
LRP5	O75197-1.2	S405F	Pathogenic	0.82
LRP5	O75197-1.2	S405G	Pathogenic	0.721
LRP5	O75197-1.2	S405H	Pathogenic	0.871
LRP5	O75197-1.2	S405I	Pathogenic	0.821
LRP5	O75197-1.2	S405K	Pathogenic	0.518
LRP5	O75197-1.2	S405L	Pathogenic	0.834
LRP5	O75197-1.2	S405M	Pathogenic	0.715
LRP5	O75197-1.2	S405N	Neutral	0.347
LRP5	O75197-1.2	S405P	Pathogenic	0.807
LRP5	O75197-1.2	S405Q	Pathogenic	0.689
LRP5	O75197-1.2	S405R	Pathogenic	0.76
LRP5	O75197-1.2	S405T	Neutral	0.405
LRP5	O75197-1.2	S405V	Pathogenic	0.889
LRP5	O75197-1.2	S405W	Pathogenic	0.898
LRP5	O75197-1.2	S405Y	Pathogenic	0.904
LRP5	O75197-1.2	G406A	Neutral	0.178
LRP5	O75197-1.2	G406C	Pathogenic	0.763
LRP5	O75197-1.2	G406D	Neutral	0.295
LRP5	O75197-1.2	G406E	Pathogenic	0.582
LRP5	O75197-1.2	G406F	Pathogenic	0.592
LRP5	O75197-1.2	G406H	Pathogenic	0.683
LRP5	O75197-1.2	G406I	Pathogenic	0.816
LRP5	O75197-1.2	G406K	Neutral	0.493
LRP5	O75197-1.2	G406L	Pathogenic	0.829
LRP5	O75197-1.2	G406M	Pathogenic	0.708
LRP5	O75197-1.2	G406N	Neutral	0.137
LRP5	O75197-1.2	G406P	Pathogenic	0.572
LRP5	O75197-1.2	G406Q	Pathogenic	0.667
LRP5	O75197-1.2	G406R	Neutral	0.485
LRP5	O75197-1.2	G406S	Neutral	0.214
LRP5	O75197-1.2	G406T	Pathogenic	0.667
LRP5	O75197-1.2	G406V	Pathogenic	0.717
LRP5	O75197-1.2	G406W	Neutral	0.232
LRP5	O75197-1.2	G406Y	Pathogenic	0.751
LRP5	O75197-1.2	A407C	Neutral	0.111
LRP5	O75197-1.2	A407D	Neutral	0.445
LRP5	O75197-1.2	A407E	Neutral	0.224
LRP5	O75197-1.2	A407F	Neutral	0.342
LRP5	O75197-1.2	A407G	Neutral	0.148
LRP5	O75197-1.2	A407H	Pathogenic	0.632
LRP5	O75197-1.2	A407I	Neutral	0.147
LRP5	O75197-1.2	A407K	Neutral	0.168
LRP5	O75197-1.2	A407L	Neutral	0.159
LRP5	O75197-1.2	A407M	Neutral	0.223
LRP5	O75197-1.2	A407N	Neutral	0.48
LRP5	O75197-1.2	A407P	Neutral	0.324
LRP5	O75197-1.2	A407Q	Neutral	0.293
LRP5	O75197-1.2	A407R	Neutral	0.163
LRP5	O75197-1.2	A407S	Neutral	0.053
LRP5	O75197-1.2	A407T	Neutral	0.178
LRP5	O75197-1.2	A407V	Neutral	0.09
LRP5	O75197-1.2	A407W	Pathogenic	0.5
LRP5	O75197-1.2	A407Y	Pathogenic	0.52
LRP5	O75197-1.2	Q408A	Pathogenic	0.947
LRP5	O75197-1.2	Q408C	Pathogenic	0.989
LRP5	O75197-1.2	Q408D	Pathogenic	0.856
LRP5	O75197-1.2	Q408E	Neutral	0.427
LRP5	O75197-1.2	Q408F	Pathogenic	0.979
LRP5	O75197-1.2	Q408G	Pathogenic	0.986
LRP5	O75197-1.2	Q408H	Pathogenic	0.88
LRP5	O75197-1.2	Q408I	Pathogenic	0.979
LRP5	O75197-1.2	Q408K	Pathogenic	0.617
LRP5	O75197-1.2	Q408L	Pathogenic	0.943
LRP5	O75197-1.2	Q408M	Pathogenic	0.731
LRP5	O75197-1.2	Q408N	Pathogenic	0.875
LRP5	O75197-1.2	Q408P	Pathogenic	0.927
LRP5	O75197-1.2	Q408R	Pathogenic	0.609
LRP5	O75197-1.2	Q408S	Pathogenic	0.889
LRP5	O75197-1.2	Q408T	Pathogenic	0.951
LRP5	O75197-1.2	Q408V	Pathogenic	0.962
LRP5	O75197-1.2	Q408W	Pathogenic	0.905
LRP5	O75197-1.2	Q408Y	Pathogenic	0.911
LRP5	O75197-1.2	T409A	Neutral	0.073
LRP5	O75197-1.2	T409C	Neutral	0.12
LRP5	O75197-1.2	T409D	Neutral	0.095
LRP5	O75197-1.2	T409E	Neutral	0.103
LRP5	O75197-1.2	T409F	Neutral	0.16
LRP5	O75197-1.2	T409G	Neutral	0.372
LRP5	O75197-1.2	T409H	Neutral	0.407
LRP5	O75197-1.2	T409I	Neutral	0.059
LRP5	O75197-1.2	T409K	Neutral	0.075
LRP5	O75197-1.2	T409L	Neutral	0.064
LRP5	O75197-1.2	T409M	Neutral	0.095
LRP5	O75197-1.2	T409N	Neutral	0.038
LRP5	O75197-1.2	T409P	Neutral	0.148
LRP5	O75197-1.2	T409Q	Neutral	0.142
LRP5	O75197-1.2	T409R	Neutral	0.072
LRP5	O75197-1.2	T409S	Neutral	0.021
LRP5	O75197-1.2	T409V	Neutral	0.035
LRP5	O75197-1.2	T409W	Neutral	0.107
LRP5	O75197-1.2	T409Y	Neutral	0.283
LRP5	O75197-1.2	L410A	Neutral	0.255
LRP5	O75197-1.2	L410C	Neutral	0.392
LRP5	O75197-1.2	L410D	Pathogenic	0.793
LRP5	O75197-1.2	L410E	Pathogenic	0.593
LRP5	O75197-1.2	L410F	Neutral	0.28
LRP5	O75197-1.2	L410G	Pathogenic	0.877
LRP5	O75197-1.2	L410H	Pathogenic	0.746
LRP5	O75197-1.2	L410I	Neutral	0.041
LRP5	O75197-1.2	L410K	Neutral	0.26
LRP5	O75197-1.2	L410M	Neutral	0.03
LRP5	O75197-1.2	L410N	Pathogenic	0.596
LRP5	O75197-1.2	L410P	Pathogenic	0.826
LRP5	O75197-1.2	L410Q	Neutral	0.412
LRP5	O75197-1.2	L410R	Neutral	0.254
LRP5	O75197-1.2	L410S	Neutral	0.436
LRP5	O75197-1.2	L410T	Neutral	0.254
LRP5	O75197-1.2	L410V	Neutral	0.081
LRP5	O75197-1.2	L410W	Pathogenic	0.695
LRP5	O75197-1.2	L410Y	Neutral	0.396
LRP5	O75197-1.2	V411A	Pathogenic	0.762
LRP5	O75197-1.2	V411C	Pathogenic	0.948
LRP5	O75197-1.2	V411D	Pathogenic	0.973
LRP5	O75197-1.2	V411E	Pathogenic	0.931
LRP5	O75197-1.2	V411F	Pathogenic	0.93
LRP5	O75197-1.2	V411G	Pathogenic	0.985
LRP5	O75197-1.2	V411H	Pathogenic	0.988
LRP5	O75197-1.2	V411I	Neutral	0.135
LRP5	O75197-1.2	V411K	Pathogenic	0.904
LRP5	O75197-1.2	V411L	Pathogenic	0.613
LRP5	O75197-1.2	V411M	Pathogenic	0.707
LRP5	O75197-1.2	V411N	Pathogenic	0.977
LRP5	O75197-1.2	V411P	Pathogenic	0.978
LRP5	O75197-1.2	V411Q	Pathogenic	0.951
LRP5	O75197-1.2	V411R	Pathogenic	0.965
LRP5	O75197-1.2	V411S	Pathogenic	0.956
LRP5	O75197-1.2	V411T	Pathogenic	0.761
LRP5	O75197-1.2	V411W	Pathogenic	0.987
LRP5	O75197-1.2	V411Y	Pathogenic	0.946
LRP5	O75197-1.2	N412A	Neutral	0.142
LRP5	O75197-1.2	N412C	Neutral	0.221
LRP5	O75197-1.2	N412D	Neutral	0.012
LRP5	O75197-1.2	N412E	Neutral	0.039
LRP5	O75197-1.2	N412F	Neutral	0.117
LRP5	O75197-1.2	N412G	Neutral	0.022
LRP5	O75197-1.2	N412H	Neutral	0.007
LRP5	O75197-1.2	N412I	Neutral	0.117
LRP5	O75197-1.2	N412K	Neutral	0.027
LRP5	O75197-1.2	N412L	Neutral	0.127
LRP5	O75197-1.2	N412M	Neutral	0.068
LRP5	O75197-1.2	N412P	Neutral	0.106
LRP5	O75197-1.2	N412Q	Neutral	0.028
LRP5	O75197-1.2	N412R	Neutral	0.026
LRP5	O75197-1.2	N412S	Neutral	0.008
LRP5	O75197-1.2	N412T	Neutral	0.019
LRP5	O75197-1.2	N412V	Neutral	0.187
LRP5	O75197-1.2	N412W	Neutral	0.202
LRP5	O75197-1.2	N412Y	Neutral	0.083
LRP5	O75197-1.2	T413A	Neutral	0.232
LRP5	O75197-1.2	T413C	Neutral	0.341
LRP5	O75197-1.2	T413D	Neutral	0.285
LRP5	O75197-1.2	T413E	Neutral	0.305
LRP5	O75197-1.2	T413F	Neutral	0.42
LRP5	O75197-1.2	T413G	Pathogenic	0.692
LRP5	O75197-1.2	T413H	Pathogenic	0.723
LRP5	O75197-1.2	T413I	Neutral	0.193
LRP5	O75197-1.2	T413K	Neutral	0.235
LRP5	O75197-1.2	T413L	Neutral	0.207
LRP5	O75197-1.2	T413M	Neutral	0.285
LRP5	O75197-1.2	T413N	Neutral	0.132
LRP5	O75197-1.2	T413P	Neutral	0.397
LRP5	O75197-1.2	T413Q	Neutral	0.387
LRP5	O75197-1.2	T413R	Neutral	0.229
LRP5	O75197-1.2	T413S	Neutral	0.075
LRP5	O75197-1.2	T413V	Neutral	0.12
LRP5	O75197-1.2	T413W	Neutral	0.314
LRP5	O75197-1.2	T413Y	Pathogenic	0.6
LRP5	O75197-1.2	E414A	Pathogenic	0.702
LRP5	O75197-1.2	E414C	Pathogenic	0.974
LRP5	O75197-1.2	E414D	Neutral	0.153
LRP5	O75197-1.2	E414F	Pathogenic	0.856
LRP5	O75197-1.2	E414G	Pathogenic	0.902
LRP5	O75197-1.2	E414H	Neutral	0.489
LRP5	O75197-1.2	E414I	Pathogenic	0.857
LRP5	O75197-1.2	E414K	Neutral	0.308
LRP5	O75197-1.2	E414L	Pathogenic	0.868
LRP5	O75197-1.2	E414M	Pathogenic	0.766
LRP5	O75197-1.2	E414N	Pathogenic	0.647
LRP5	O75197-1.2	E414P	Pathogenic	0.629
LRP5	O75197-1.2	E414Q	Neutral	0.125
LRP5	O75197-1.2	E414R	Pathogenic	0.567
LRP5	O75197-1.2	E414S	Pathogenic	0.516
LRP5	O75197-1.2	E414T	Pathogenic	0.72
LRP5	O75197-1.2	E414V	Pathogenic	0.772
LRP5	O75197-1.2	E414W	Pathogenic	0.79
LRP5	O75197-1.2	E414Y	Pathogenic	0.803
LRP5	O75197-1.2	I415A	Pathogenic	0.788
LRP5	O75197-1.2	I415C	Pathogenic	0.875
LRP5	O75197-1.2	I415D	Pathogenic	0.932
LRP5	O75197-1.2	I415E	Pathogenic	0.941
LRP5	O75197-1.2	I415F	Pathogenic	0.832
LRP5	O75197-1.2	I415G	Pathogenic	0.987
LRP5	O75197-1.2	I415H	Pathogenic	0.97
LRP5	O75197-1.2	I415K	Pathogenic	0.921
LRP5	O75197-1.2	I415L	Neutral	0.335
LRP5	O75197-1.2	I415M	Pathogenic	0.502
LRP5	O75197-1.2	I415N	Pathogenic	0.941
LRP5	O75197-1.2	I415P	Pathogenic	0.981
LRP5	O75197-1.2	I415Q	Pathogenic	0.959
LRP5	O75197-1.2	I415R	Pathogenic	0.918
LRP5	O75197-1.2	I415S	Pathogenic	0.894
LRP5	O75197-1.2	I415T	Pathogenic	0.787
LRP5	O75197-1.2	I415V	Neutral	0.094
LRP5	O75197-1.2	I415W	Pathogenic	0.989
LRP5	O75197-1.2	I415Y	Pathogenic	0.877
LRP5	O75197-1.2	N416A	Neutral	0.276
LRP5	O75197-1.2	N416C	Neutral	0.395
LRP5	O75197-1.2	N416D	Neutral	0.027
LRP5	O75197-1.2	N416E	Neutral	0.084
LRP5	O75197-1.2	N416F	Neutral	0.233
LRP5	O75197-1.2	N416G	Neutral	0.05
LRP5	O75197-1.2	N416H	Neutral	0.016
LRP5	O75197-1.2	N416I	Neutral	0.234
LRP5	O75197-1.2	N416K	Neutral	0.061
LRP5	O75197-1.2	N416L	Neutral	0.25
LRP5	O75197-1.2	N416M	Neutral	0.143
LRP5	O75197-1.2	N416P	Neutral	0.215
LRP5	O75197-1.2	N416Q	Neutral	0.063
LRP5	O75197-1.2	N416R	Neutral	0.059
LRP5	O75197-1.2	N416S	Neutral	0.018
LRP5	O75197-1.2	N416T	Neutral	0.043
LRP5	O75197-1.2	N416V	Neutral	0.347
LRP5	O75197-1.2	N416W	Neutral	0.369
LRP5	O75197-1.2	N416Y	Neutral	0.172
LRP5	O75197-1.2	D417A	Neutral	0.451
LRP5	O75197-1.2	D417C	Pathogenic	0.585
LRP5	O75197-1.2	D417E	Neutral	0.022
LRP5	O75197-1.2	D417F	Neutral	0.392
LRP5	O75197-1.2	D417G	Neutral	0.257
LRP5	O75197-1.2	D417H	Neutral	0.239
LRP5	O75197-1.2	D417I	Neutral	0.393
LRP5	O75197-1.2	D417K	Neutral	0.36
LRP5	O75197-1.2	D417L	Pathogenic	0.683
LRP5	O75197-1.2	D417M	Pathogenic	0.519
LRP5	O75197-1.2	D417N	Neutral	0.064
LRP5	O75197-1.2	D417P	Neutral	0.163
LRP5	O75197-1.2	D417Q	Neutral	0.125
LRP5	O75197-1.2	D417R	Pathogenic	0.624
LRP5	O75197-1.2	D417S	Neutral	0.109
LRP5	O75197-1.2	D417T	Neutral	0.227
LRP5	O75197-1.2	D417V	Pathogenic	0.53
LRP5	O75197-1.2	D417W	Pathogenic	0.553
LRP5	O75197-1.2	D417Y	Pathogenic	0.572
LRP5	O75197-1.2	P418A	Pathogenic	0.994
LRP5	O75197-1.2	P418C	Pathogenic	0.999
LRP5	O75197-1.2	P418D	Pathogenic	0.985
LRP5	O75197-1.2	P418E	Pathogenic	0.986
LRP5	O75197-1.2	P418F	Pathogenic	1.0
LRP5	O75197-1.2	P418G	Pathogenic	0.997
LRP5	O75197-1.2	P418H	Pathogenic	0.998
LRP5	O75197-1.2	P418I	Pathogenic	0.999
LRP5	O75197-1.2	P418K	Pathogenic	0.98
LRP5	O75197-1.2	P418L	Pathogenic	0.999
LRP5	O75197-1.2	P418M	Pathogenic	0.998
LRP5	O75197-1.2	P418N	Pathogenic	0.996
LRP5	O75197-1.2	P418Q	Pathogenic	0.99
LRP5	O75197-1.2	P418R	Pathogenic	0.993
LRP5	O75197-1.2	P418S	Pathogenic	0.992
LRP5	O75197-1.2	P418T	Pathogenic	0.994
LRP5	O75197-1.2	P418V	Pathogenic	0.998
LRP5	O75197-1.2	P418W	Pathogenic	0.999
LRP5	O75197-1.2	P418Y	Pathogenic	0.999
LRP5	O75197-1.2	D419A	Pathogenic	0.987
LRP5	O75197-1.2	D419C	Pathogenic	0.993
LRP5	O75197-1.2	D419E	Pathogenic	0.68
LRP5	O75197-1.2	D419F	Pathogenic	0.984
LRP5	O75197-1.2	D419G	Pathogenic	0.97
LRP5	O75197-1.2	D419H	Pathogenic	0.967
LRP5	O75197-1.2	D419I	Pathogenic	0.984
LRP5	O75197-1.2	D419K	Pathogenic	0.981
LRP5	O75197-1.2	D419L	Pathogenic	0.995
LRP5	O75197-1.2	D419M	Pathogenic	0.99
LRP5	O75197-1.2	D419N	Pathogenic	0.865
LRP5	O75197-1.2	D419P	Pathogenic	0.948
LRP5	O75197-1.2	D419Q	Pathogenic	0.931
LRP5	O75197-1.2	D419R	Pathogenic	0.994
LRP5	O75197-1.2	D419S	Pathogenic	0.92
LRP5	O75197-1.2	D419T	Pathogenic	0.965
LRP5	O75197-1.2	D419V	Pathogenic	0.991
LRP5	O75197-1.2	D419W	Pathogenic	0.991
LRP5	O75197-1.2	D419Y	Pathogenic	0.992
LRP5	O75197-1.2	G420A	Pathogenic	0.98
LRP5	O75197-1.2	G420C	Pathogenic	0.999
LRP5	O75197-1.2	G420D	Pathogenic	0.99
LRP5	O75197-1.2	G420E	Pathogenic	0.997
LRP5	O75197-1.2	G420F	Pathogenic	0.997
LRP5	O75197-1.2	G420H	Pathogenic	0.998
LRP5	O75197-1.2	G420I	Pathogenic	0.999
LRP5	O75197-1.2	G420K	Pathogenic	0.995
LRP5	O75197-1.2	G420L	Pathogenic	0.999
LRP5	O75197-1.2	G420M	Pathogenic	0.998
LRP5	O75197-1.2	G420N	Pathogenic	0.973
LRP5	O75197-1.2	G420P	Pathogenic	0.997
LRP5	O75197-1.2	G420Q	Pathogenic	0.998
LRP5	O75197-1.2	G420R	Pathogenic	0.995
LRP5	O75197-1.2	G420S	Pathogenic	0.984
LRP5	O75197-1.2	G420T	Pathogenic	0.998
LRP5	O75197-1.2	G420V	Pathogenic	0.998
LRP5	O75197-1.2	G420W	Pathogenic	0.986
LRP5	O75197-1.2	G420Y	Pathogenic	0.999
LRP5	O75197-1.2	I421A	Pathogenic	0.949
LRP5	O75197-1.2	I421C	Pathogenic	0.972
LRP5	O75197-1.2	I421D	Pathogenic	0.986
LRP5	O75197-1.2	I421E	Pathogenic	0.988
LRP5	O75197-1.2	I421F	Pathogenic	0.961
LRP5	O75197-1.2	I421G	Pathogenic	0.997
LRP5	O75197-1.2	I421H	Pathogenic	0.994
LRP5	O75197-1.2	I421K	Pathogenic	0.983
LRP5	O75197-1.2	I421L	Pathogenic	0.717
LRP5	O75197-1.2	I421M	Pathogenic	0.835
LRP5	O75197-1.2	I421N	Pathogenic	0.988
LRP5	O75197-1.2	I421P	Pathogenic	0.996
LRP5	O75197-1.2	I421Q	Pathogenic	0.992
LRP5	O75197-1.2	I421R	Pathogenic	0.983
LRP5	O75197-1.2	I421S	Pathogenic	0.977
LRP5	O75197-1.2	I421T	Pathogenic	0.949
LRP5	O75197-1.2	I421V	Neutral	0.344
LRP5	O75197-1.2	I421W	Pathogenic	0.998
LRP5	O75197-1.2	I421Y	Pathogenic	0.973
LRP5	O75197-1.2	A422C	Pathogenic	0.982
LRP5	O75197-1.2	A422D	Pathogenic	0.997
LRP5	O75197-1.2	A422E	Pathogenic	0.992
LRP5	O75197-1.2	A422F	Pathogenic	0.996
LRP5	O75197-1.2	A422G	Pathogenic	0.987
LRP5	O75197-1.2	A422H	Pathogenic	0.999
LRP5	O75197-1.2	A422I	Pathogenic	0.987
LRP5	O75197-1.2	A422K	Pathogenic	0.989
LRP5	O75197-1.2	A422L	Pathogenic	0.988
LRP5	O75197-1.2	A422M	Pathogenic	0.992
LRP5	O75197-1.2	A422N	Pathogenic	0.998
LRP5	O75197-1.2	A422P	Pathogenic	0.995
LRP5	O75197-1.2	A422Q	Pathogenic	0.995
LRP5	O75197-1.2	A422R	Pathogenic	0.988
LRP5	O75197-1.2	A422S	Pathogenic	0.961
LRP5	O75197-1.2	A422T	Pathogenic	0.99
LRP5	O75197-1.2	A422V	Pathogenic	0.977
LRP5	O75197-1.2	A422W	Pathogenic	0.998
LRP5	O75197-1.2	A422Y	Pathogenic	0.998
LRP5	O75197-1.2	V423A	Pathogenic	0.925
LRP5	O75197-1.2	V423C	Pathogenic	0.986
LRP5	O75197-1.2	V423D	Pathogenic	0.993
LRP5	O75197-1.2	V423E	Pathogenic	0.981
LRP5	O75197-1.2	V423F	Pathogenic	0.981
LRP5	O75197-1.2	V423G	Pathogenic	0.996
LRP5	O75197-1.2	V423H	Pathogenic	0.997
LRP5	O75197-1.2	V423I	Neutral	0.376
LRP5	O75197-1.2	V423K	Pathogenic	0.973
LRP5	O75197-1.2	V423L	Pathogenic	0.86
LRP5	O75197-1.2	V423M	Pathogenic	0.903
LRP5	O75197-1.2	V423N	Pathogenic	0.994
LRP5	O75197-1.2	V423P	Pathogenic	0.994
LRP5	O75197-1.2	V423Q	Pathogenic	0.987
LRP5	O75197-1.2	V423R	Pathogenic	0.991
LRP5	O75197-1.2	V423S	Pathogenic	0.988
LRP5	O75197-1.2	V423T	Pathogenic	0.925
LRP5	O75197-1.2	V423W	Pathogenic	0.997
LRP5	O75197-1.2	V423Y	Pathogenic	0.985
LRP5	O75197-1.2	D424A	Pathogenic	0.994
LRP5	O75197-1.2	D424C	Pathogenic	0.996
LRP5	O75197-1.2	D424E	Pathogenic	0.819
LRP5	O75197-1.2	D424F	Pathogenic	0.992
LRP5	O75197-1.2	D424G	Pathogenic	0.986
LRP5	O75197-1.2	D424H	Pathogenic	0.984
LRP5	O75197-1.2	D424I	Pathogenic	0.992
LRP5	O75197-1.2	D424K	Pathogenic	0.991
LRP5	O75197-1.2	D424L	Pathogenic	0.998
LRP5	O75197-1.2	D424M	Pathogenic	0.995
LRP5	O75197-1.2	D424N	Pathogenic	0.931
LRP5	O75197-1.2	D424P	Pathogenic	0.975
LRP5	O75197-1.2	D424Q	Pathogenic	0.966
LRP5	O75197-1.2	D424R	Pathogenic	0.997
LRP5	O75197-1.2	D424S	Pathogenic	0.961
LRP5	O75197-1.2	D424T	Pathogenic	0.983
LRP5	O75197-1.2	D424V	Pathogenic	0.996
LRP5	O75197-1.2	D424W	Pathogenic	0.996
LRP5	O75197-1.2	D424Y	Pathogenic	0.996
LRP5	O75197-1.2	W425A	Pathogenic	0.999
LRP5	O75197-1.2	W425C	Pathogenic	0.998
LRP5	O75197-1.2	W425D	Pathogenic	0.999
LRP5	O75197-1.2	W425E	Pathogenic	0.998
LRP5	O75197-1.2	W425F	Pathogenic	0.981
LRP5	O75197-1.2	W425G	Pathogenic	0.996
LRP5	O75197-1.2	W425H	Pathogenic	0.997
LRP5	O75197-1.2	W425I	Pathogenic	1.0
LRP5	O75197-1.2	W425K	Pathogenic	0.997
LRP5	O75197-1.2	W425L	Pathogenic	0.999
LRP5	O75197-1.2	W425M	Pathogenic	0.996
LRP5	O75197-1.2	W425N	Pathogenic	0.999
LRP5	O75197-1.2	W425P	Pathogenic	1.0
LRP5	O75197-1.2	W425Q	Pathogenic	0.996
LRP5	O75197-1.2	W425R	Pathogenic	0.997
LRP5	O75197-1.2	W425S	Pathogenic	0.999
LRP5	O75197-1.2	W425T	Pathogenic	0.997
LRP5	O75197-1.2	W425V	Pathogenic	1.0
LRP5	O75197-1.2	W425Y	Pathogenic	0.89
LRP5	O75197-1.2	V426A	Pathogenic	0.727
LRP5	O75197-1.2	V426C	Pathogenic	0.939
LRP5	O75197-1.2	V426D	Pathogenic	0.967
LRP5	O75197-1.2	V426E	Pathogenic	0.918
LRP5	O75197-1.2	V426F	Pathogenic	0.917
LRP5	O75197-1.2	V426G	Pathogenic	0.982
LRP5	O75197-1.2	V426H	Pathogenic	0.985
LRP5	O75197-1.2	V426I	Neutral	0.115
LRP5	O75197-1.2	V426K	Pathogenic	0.887
LRP5	O75197-1.2	V426L	Pathogenic	0.569
LRP5	O75197-1.2	V426M	Pathogenic	0.668
LRP5	O75197-1.2	V426N	Pathogenic	0.972
LRP5	O75197-1.2	V426P	Pathogenic	0.974
LRP5	O75197-1.2	V426Q	Pathogenic	0.942
LRP5	O75197-1.2	V426R	Pathogenic	0.958
LRP5	O75197-1.2	V426S	Pathogenic	0.948
LRP5	O75197-1.2	V426T	Pathogenic	0.726
LRP5	O75197-1.2	V426W	Pathogenic	0.985
LRP5	O75197-1.2	V426Y	Pathogenic	0.936
LRP5	O75197-1.2	A427C	Pathogenic	0.931
LRP5	O75197-1.2	A427D	Pathogenic	0.989
LRP5	O75197-1.2	A427E	Pathogenic	0.969
LRP5	O75197-1.2	A427F	Pathogenic	0.982
LRP5	O75197-1.2	A427G	Pathogenic	0.949
LRP5	O75197-1.2	A427H	Pathogenic	0.995
LRP5	O75197-1.2	A427I	Pathogenic	0.949
LRP5	O75197-1.2	A427K	Pathogenic	0.956
LRP5	O75197-1.2	A427L	Pathogenic	0.953
LRP5	O75197-1.2	A427M	Pathogenic	0.969
LRP5	O75197-1.2	A427N	Pathogenic	0.99
LRP5	O75197-1.2	A427P	Pathogenic	0.981
LRP5	O75197-1.2	A427Q	Pathogenic	0.978
LRP5	O75197-1.2	A427R	Pathogenic	0.954
LRP5	O75197-1.2	A427S	Pathogenic	0.859
LRP5	O75197-1.2	A427T	Pathogenic	0.959
LRP5	O75197-1.2	A427V	Pathogenic	0.914
LRP5	O75197-1.2	A427W	Pathogenic	0.991
LRP5	O75197-1.2	A427Y	Pathogenic	0.991
LRP5	O75197-1.2	R428A	Pathogenic	0.971
LRP5	O75197-1.2	R428C	Pathogenic	0.994
LRP5	O75197-1.2	R428D	Pathogenic	0.996
LRP5	O75197-1.2	R428E	Pathogenic	0.965
LRP5	O75197-1.2	R428F	Pathogenic	0.989
LRP5	O75197-1.2	R428G	Pathogenic	0.992
LRP5	O75197-1.2	R428H	Pathogenic	0.934
LRP5	O75197-1.2	R428I	Pathogenic	0.989
LRP5	O75197-1.2	R428K	Pathogenic	0.81
LRP5	O75197-1.2	R428L	Pathogenic	0.97
LRP5	O75197-1.2	R428M	Pathogenic	0.942
LRP5	O75197-1.2	R428N	Pathogenic	0.963
LRP5	O75197-1.2	R428P	Pathogenic	0.987
LRP5	O75197-1.2	R428Q	Pathogenic	0.863
LRP5	O75197-1.2	R428S	Pathogenic	0.979
LRP5	O75197-1.2	R428T	Pathogenic	0.974
LRP5	O75197-1.2	R428V	Pathogenic	0.993
LRP5	O75197-1.2	R428W	Pathogenic	0.984
LRP5	O75197-1.2	R428Y	Pathogenic	0.985
LRP5	O75197-1.2	N429A	Pathogenic	0.997
LRP5	O75197-1.2	N429C	Pathogenic	0.998
LRP5	O75197-1.2	N429D	Pathogenic	0.962
LRP5	O75197-1.2	N429E	Pathogenic	0.989
LRP5	O75197-1.2	N429F	Pathogenic	0.997
LRP5	O75197-1.2	N429G	Pathogenic	0.98
LRP5	O75197-1.2	N429H	Pathogenic	0.938
LRP5	O75197-1.2	N429I	Pathogenic	0.997
LRP5	O75197-1.2	N429K	Pathogenic	0.984
LRP5	O75197-1.2	N429L	Pathogenic	0.997
LRP5	O75197-1.2	N429M	Pathogenic	0.994
LRP5	O75197-1.2	N429P	Pathogenic	0.996
LRP5	O75197-1.2	N429Q	Pathogenic	0.984
LRP5	O75197-1.2	N429R	Pathogenic	0.983
LRP5	O75197-1.2	N429S	Pathogenic	0.946
LRP5	O75197-1.2	N429T	Pathogenic	0.977
LRP5	O75197-1.2	N429V	Pathogenic	0.998
LRP5	O75197-1.2	N429W	Pathogenic	0.998
LRP5	O75197-1.2	N429Y	Pathogenic	0.995
LRP5	O75197-1.2	L430A	Pathogenic	0.976
LRP5	O75197-1.2	L430C	Pathogenic	0.987
LRP5	O75197-1.2	L430D	Pathogenic	0.998
LRP5	O75197-1.2	L430E	Pathogenic	0.994
LRP5	O75197-1.2	L430F	Pathogenic	0.979
LRP5	O75197-1.2	L430G	Pathogenic	0.999
LRP5	O75197-1.2	L430H	Pathogenic	0.997
LRP5	O75197-1.2	L430I	Pathogenic	0.833
LRP5	O75197-1.2	L430K	Pathogenic	0.976
LRP5	O75197-1.2	L430M	Pathogenic	0.782
LRP5	O75197-1.2	L430N	Pathogenic	0.994
LRP5	O75197-1.2	L430P	Pathogenic	0.998
LRP5	O75197-1.2	L430Q	Pathogenic	0.988
LRP5	O75197-1.2	L430R	Pathogenic	0.976
LRP5	O75197-1.2	L430S	Pathogenic	0.989
LRP5	O75197-1.2	L430T	Pathogenic	0.976
LRP5	O75197-1.2	L430V	Pathogenic	0.913
LRP5	O75197-1.2	L430W	Pathogenic	0.996
LRP5	O75197-1.2	L430Y	Pathogenic	0.987
LRP5	O75197-1.2	Y431A	Pathogenic	0.999
LRP5	O75197-1.2	Y431C	Pathogenic	0.999
LRP5	O75197-1.2	Y431D	Pathogenic	0.999
LRP5	O75197-1.2	Y431E	Pathogenic	0.997
LRP5	O75197-1.2	Y431F	Pathogenic	0.747
LRP5	O75197-1.2	Y431G	Pathogenic	0.999
LRP5	O75197-1.2	Y431H	Pathogenic	0.897
LRP5	O75197-1.2	Y431I	Pathogenic	0.996
LRP5	O75197-1.2	Y431K	Pathogenic	0.996
LRP5	O75197-1.2	Y431L	Pathogenic	0.996
LRP5	O75197-1.2	Y431M	Pathogenic	0.998
LRP5	O75197-1.2	Y431N	Pathogenic	0.997
LRP5	O75197-1.2	Y431P	Pathogenic	1.0
LRP5	O75197-1.2	Y431Q	Pathogenic	0.994
LRP5	O75197-1.2	Y431R	Pathogenic	0.996
LRP5	O75197-1.2	Y431S	Pathogenic	0.998
LRP5	O75197-1.2	Y431T	Pathogenic	0.999
LRP5	O75197-1.2	Y431V	Pathogenic	0.998
LRP5	O75197-1.2	Y431W	Pathogenic	0.853
LRP5	O75197-1.2	W432A	Pathogenic	0.999
LRP5	O75197-1.2	W432C	Pathogenic	0.998
LRP5	O75197-1.2	W432D	Pathogenic	0.999
LRP5	O75197-1.2	W432E	Pathogenic	0.998
LRP5	O75197-1.2	W432F	Pathogenic	0.981
LRP5	O75197-1.2	W432G	Pathogenic	0.996
LRP5	O75197-1.2	W432H	Pathogenic	0.997
LRP5	O75197-1.2	W432I	Pathogenic	1.0
LRP5	O75197-1.2	W432K	Pathogenic	0.997
LRP5	O75197-1.2	W432L	Pathogenic	0.999
LRP5	O75197-1.2	W432M	Pathogenic	0.996
LRP5	O75197-1.2	W432N	Pathogenic	0.999
LRP5	O75197-1.2	W432P	Pathogenic	1.0
LRP5	O75197-1.2	W432Q	Pathogenic	0.996
LRP5	O75197-1.2	W432R	Pathogenic	0.997
LRP5	O75197-1.2	W432S	Pathogenic	0.999
LRP5	O75197-1.2	W432T	Pathogenic	0.997
LRP5	O75197-1.2	W432V	Pathogenic	1.0
LRP5	O75197-1.2	W432Y	Pathogenic	0.89
LRP5	O75197-1.2	T433A	Pathogenic	0.989
LRP5	O75197-1.2	T433C	Pathogenic	0.993
LRP5	O75197-1.2	T433D	Pathogenic	0.991
LRP5	O75197-1.2	T433E	Pathogenic	0.992
LRP5	O75197-1.2	T433F	Pathogenic	0.995
LRP5	O75197-1.2	T433G	Pathogenic	0.998
LRP5	O75197-1.2	T433H	Pathogenic	0.999
LRP5	O75197-1.2	T433I	Pathogenic	0.986
LRP5	O75197-1.2	T433K	Pathogenic	0.989
LRP5	O75197-1.2	T433L	Pathogenic	0.987
LRP5	O75197-1.2	T433M	Pathogenic	0.991
LRP5	O75197-1.2	T433N	Pathogenic	0.978
LRP5	O75197-1.2	T433P	Pathogenic	0.995
LRP5	O75197-1.2	T433Q	Pathogenic	0.995
LRP5	O75197-1.2	T433R	Pathogenic	0.989
LRP5	O75197-1.2	T433S	Pathogenic	0.959
LRP5	O75197-1.2	T433V	Pathogenic	0.975
LRP5	O75197-1.2	T433W	Pathogenic	0.993
LRP5	O75197-1.2	T433Y	Pathogenic	0.998
LRP5	O75197-1.2	D434A	Pathogenic	0.994
LRP5	O75197-1.2	D434C	Pathogenic	0.996
LRP5	O75197-1.2	D434E	Pathogenic	0.819
LRP5	O75197-1.2	D434F	Pathogenic	0.992
LRP5	O75197-1.2	D434G	Pathogenic	0.986
LRP5	O75197-1.2	D434H	Pathogenic	0.984
LRP5	O75197-1.2	D434I	Pathogenic	0.992
LRP5	O75197-1.2	D434K	Pathogenic	0.991
LRP5	O75197-1.2	D434L	Pathogenic	0.998
LRP5	O75197-1.2	D434M	Pathogenic	0.995
LRP5	O75197-1.2	D434N	Pathogenic	0.931
LRP5	O75197-1.2	D434P	Pathogenic	0.975
LRP5	O75197-1.2	D434Q	Pathogenic	0.966
LRP5	O75197-1.2	D434R	Pathogenic	0.997
LRP5	O75197-1.2	D434S	Pathogenic	0.961
LRP5	O75197-1.2	D434T	Pathogenic	0.983
LRP5	O75197-1.2	D434V	Pathogenic	0.996
LRP5	O75197-1.2	D434W	Pathogenic	0.996
LRP5	O75197-1.2	D434Y	Pathogenic	0.996
LRP5	O75197-1.2	T435A	Pathogenic	0.988
LRP5	O75197-1.2	T435C	Pathogenic	0.993
LRP5	O75197-1.2	T435D	Pathogenic	0.991
LRP5	O75197-1.2	T435E	Pathogenic	0.992
LRP5	O75197-1.2	T435F	Pathogenic	0.995
LRP5	O75197-1.2	T435G	Pathogenic	0.998
LRP5	O75197-1.2	T435H	Pathogenic	0.999
LRP5	O75197-1.2	T435I	Pathogenic	0.985
LRP5	O75197-1.2	T435K	Pathogenic	0.988
LRP5	O75197-1.2	T435L	Pathogenic	0.986
LRP5	O75197-1.2	T435M	Pathogenic	0.991
LRP5	O75197-1.2	T435N	Pathogenic	0.976
LRP5	O75197-1.2	T435P	Pathogenic	0.994
LRP5	O75197-1.2	T435Q	Pathogenic	0.994
LRP5	O75197-1.2	T435R	Pathogenic	0.988
LRP5	O75197-1.2	T435S	Pathogenic	0.956
LRP5	O75197-1.2	T435V	Pathogenic	0.973
LRP5	O75197-1.2	T435W	Pathogenic	0.992
LRP5	O75197-1.2	T435Y	Pathogenic	0.998
LRP5	O75197-1.2	G436A	Pathogenic	0.978
LRP5	O75197-1.2	G436C	Pathogenic	0.998
LRP5	O75197-1.2	G436D	Pathogenic	0.988
LRP5	O75197-1.2	G436E	Pathogenic	0.996
LRP5	O75197-1.2	G436F	Pathogenic	0.997
LRP5	O75197-1.2	G436H	Pathogenic	0.998
LRP5	O75197-1.2	G436I	Pathogenic	0.999
LRP5	O75197-1.2	G436K	Pathogenic	0.995
LRP5	O75197-1.2	G436L	Pathogenic	0.999
LRP5	O75197-1.2	G436M	Pathogenic	0.998
LRP5	O75197-1.2	G436N	Pathogenic	0.97
LRP5	O75197-1.2	G436P	Pathogenic	0.996
LRP5	O75197-1.2	G436Q	Pathogenic	0.998
LRP5	O75197-1.2	G436R	Pathogenic	0.995
LRP5	O75197-1.2	G436S	Pathogenic	0.982
LRP5	O75197-1.2	G436T	Pathogenic	0.998
LRP5	O75197-1.2	G436V	Pathogenic	0.998
LRP5	O75197-1.2	G436W	Pathogenic	0.984
LRP5	O75197-1.2	G436Y	Pathogenic	0.998
LRP5	O75197-1.2	T437A	Pathogenic	0.977
LRP5	O75197-1.2	T437C	Pathogenic	0.986
LRP5	O75197-1.2	T437D	Pathogenic	0.983
LRP5	O75197-1.2	T437E	Pathogenic	0.984
LRP5	O75197-1.2	T437F	Pathogenic	0.99
LRP5	O75197-1.2	T437G	Pathogenic	0.997
LRP5	O75197-1.2	T437H	Pathogenic	0.997
LRP5	O75197-1.2	T437I	Pathogenic	0.971
LRP5	O75197-1.2	T437K	Pathogenic	0.977
LRP5	O75197-1.2	T437L	Pathogenic	0.974
LRP5	O75197-1.2	T437M	Pathogenic	0.982
LRP5	O75197-1.2	T437N	Pathogenic	0.955
LRP5	O75197-1.2	T437P	Pathogenic	0.989
LRP5	O75197-1.2	T437Q	Pathogenic	0.989
LRP5	O75197-1.2	T437R	Pathogenic	0.977
LRP5	O75197-1.2	T437S	Pathogenic	0.919
LRP5	O75197-1.2	T437V	Pathogenic	0.951
LRP5	O75197-1.2	T437W	Pathogenic	0.985
LRP5	O75197-1.2	T437Y	Pathogenic	0.995
LRP5	O75197-1.2	D438A	Pathogenic	0.993
LRP5	O75197-1.2	D438C	Pathogenic	0.996
LRP5	O75197-1.2	D438E	Pathogenic	0.802
LRP5	O75197-1.2	D438F	Pathogenic	0.991
LRP5	O75197-1.2	D438G	Pathogenic	0.984
LRP5	O75197-1.2	D438H	Pathogenic	0.983
LRP5	O75197-1.2	D438I	Pathogenic	0.991
LRP5	O75197-1.2	D438K	Pathogenic	0.99
LRP5	O75197-1.2	D438L	Pathogenic	0.997
LRP5	O75197-1.2	D438M	Pathogenic	0.995
LRP5	O75197-1.2	D438N	Pathogenic	0.924
LRP5	O75197-1.2	D438P	Pathogenic	0.972
LRP5	O75197-1.2	D438Q	Pathogenic	0.962
LRP5	O75197-1.2	D438R	Pathogenic	0.997
LRP5	O75197-1.2	D438S	Pathogenic	0.956
LRP5	O75197-1.2	D438T	Pathogenic	0.981
LRP5	O75197-1.2	D438V	Pathogenic	0.995
LRP5	O75197-1.2	D438W	Pathogenic	0.996
LRP5	O75197-1.2	D438Y	Pathogenic	0.996
LRP5	O75197-1.2	R439A	Pathogenic	0.985
LRP5	O75197-1.2	R439C	Pathogenic	0.997
LRP5	O75197-1.2	R439D	Pathogenic	0.998
LRP5	O75197-1.2	R439E	Pathogenic	0.981
LRP5	O75197-1.2	R439F	Pathogenic	0.994
LRP5	O75197-1.2	R439G	Pathogenic	0.996
LRP5	O75197-1.2	R439H	Pathogenic	0.964
LRP5	O75197-1.2	R439I	Pathogenic	0.994
LRP5	O75197-1.2	R439K	Pathogenic	0.891
LRP5	O75197-1.2	R439L	Pathogenic	0.984
LRP5	O75197-1.2	R439M	Pathogenic	0.969
LRP5	O75197-1.2	R439N	Pathogenic	0.98
LRP5	O75197-1.2	R439P	Pathogenic	0.993
LRP5	O75197-1.2	R439Q	Pathogenic	0.923
LRP5	O75197-1.2	R439S	Pathogenic	0.989
LRP5	O75197-1.2	R439T	Pathogenic	0.986
LRP5	O75197-1.2	R439V	Pathogenic	0.996
LRP5	O75197-1.2	R439W	Pathogenic	0.992
LRP5	O75197-1.2	R439Y	Pathogenic	0.992
LRP5	O75197-1.2	I440A	Pathogenic	0.98
LRP5	O75197-1.2	I440C	Pathogenic	0.989
LRP5	O75197-1.2	I440D	Pathogenic	0.994
LRP5	O75197-1.2	I440E	Pathogenic	0.995
LRP5	O75197-1.2	I440F	Pathogenic	0.985
LRP5	O75197-1.2	I440G	Pathogenic	0.999
LRP5	O75197-1.2	I440H	Pathogenic	0.998
LRP5	O75197-1.2	I440K	Pathogenic	0.994
LRP5	O75197-1.2	I440L	Pathogenic	0.869
LRP5	O75197-1.2	I440M	Pathogenic	0.93
LRP5	O75197-1.2	I440N	Pathogenic	0.995
LRP5	O75197-1.2	I440P	Pathogenic	0.999
LRP5	O75197-1.2	I440Q	Pathogenic	0.997
LRP5	O75197-1.2	I440R	Pathogenic	0.993
LRP5	O75197-1.2	I440S	Pathogenic	0.991
LRP5	O75197-1.2	I440T	Pathogenic	0.98
LRP5	O75197-1.2	I440V	Pathogenic	0.579
LRP5	O75197-1.2	I440W	Pathogenic	0.999
LRP5	O75197-1.2	I440Y	Pathogenic	0.989
LRP5	O75197-1.2	E441A	Pathogenic	0.99
LRP5	O75197-1.2	E441C	Pathogenic	0.999
LRP5	O75197-1.2	E441D	Pathogenic	0.884
LRP5	O75197-1.2	E441F	Pathogenic	0.996
LRP5	O75197-1.2	E441G	Pathogenic	0.997
LRP5	O75197-1.2	E441H	Pathogenic	0.976
LRP5	O75197-1.2	E441I	Pathogenic	0.996
LRP5	O75197-1.2	E441K	Pathogenic	0.949
LRP5	O75197-1.2	E441L	Pathogenic	0.996
LRP5	O75197-1.2	E441M	Pathogenic	0.993
LRP5	O75197-1.2	E441N	Pathogenic	0.987
LRP5	O75197-1.2	E441P	Pathogenic	0.986
LRP5	O75197-1.2	E441Q	Pathogenic	0.857
LRP5	O75197-1.2	E441R	Pathogenic	0.982
LRP5	O75197-1.2	E441S	Pathogenic	0.978
LRP5	O75197-1.2	E441T	Pathogenic	0.991
LRP5	O75197-1.2	E441V	Pathogenic	0.993
LRP5	O75197-1.2	E441W	Pathogenic	0.994
LRP5	O75197-1.2	E441Y	Pathogenic	0.994
LRP5	O75197-1.2	V442A	Pathogenic	0.97
LRP5	O75197-1.2	V442C	Pathogenic	0.995
LRP5	O75197-1.2	V442D	Pathogenic	0.997
LRP5	O75197-1.2	V442E	Pathogenic	0.993
LRP5	O75197-1.2	V442F	Pathogenic	0.993
LRP5	O75197-1.2	V442G	Pathogenic	0.998
LRP5	O75197-1.2	V442H	Pathogenic	0.999
LRP5	O75197-1.2	V442I	Pathogenic	0.61
LRP5	O75197-1.2	V442K	Pathogenic	0.989
LRP5	O75197-1.2	V442L	Pathogenic	0.941
LRP5	O75197-1.2	V442M	Pathogenic	0.96
LRP5	O75197-1.2	V442N	Pathogenic	0.998
LRP5	O75197-1.2	V442P	Pathogenic	0.998
LRP5	O75197-1.2	V442Q	Pathogenic	0.995
LRP5	O75197-1.2	V442R	Pathogenic	0.996
LRP5	O75197-1.2	V442S	Pathogenic	0.995
LRP5	O75197-1.2	V442T	Pathogenic	0.97
LRP5	O75197-1.2	V442W	Pathogenic	0.999
LRP5	O75197-1.2	V442Y	Pathogenic	0.994
LRP5	O75197-1.2	T443A	Pathogenic	0.87
LRP5	O75197-1.2	T443C	Pathogenic	0.92
LRP5	O75197-1.2	T443D	Pathogenic	0.899
LRP5	O75197-1.2	T443E	Pathogenic	0.907
LRP5	O75197-1.2	T443F	Pathogenic	0.941
LRP5	O75197-1.2	T443G	Pathogenic	0.98
LRP5	O75197-1.2	T443H	Pathogenic	0.983
LRP5	O75197-1.2	T443I	Pathogenic	0.842
LRP5	O75197-1.2	T443K	Pathogenic	0.872
LRP5	O75197-1.2	T443L	Pathogenic	0.853
LRP5	O75197-1.2	T443M	Pathogenic	0.899
LRP5	O75197-1.2	T443N	Pathogenic	0.772
LRP5	O75197-1.2	T443P	Pathogenic	0.936
LRP5	O75197-1.2	T443Q	Pathogenic	0.934
LRP5	O75197-1.2	T443R	Pathogenic	0.868
LRP5	O75197-1.2	T443S	Pathogenic	0.642
LRP5	O75197-1.2	T443V	Pathogenic	0.753
LRP5	O75197-1.2	T443W	Pathogenic	0.911
LRP5	O75197-1.2	T443Y	Pathogenic	0.971
LRP5	O75197-1.2	R444A	Pathogenic	0.979
LRP5	O75197-1.2	R444C	Pathogenic	0.996
LRP5	O75197-1.2	R444D	Pathogenic	0.997
LRP5	O75197-1.2	R444E	Pathogenic	0.975
LRP5	O75197-1.2	R444F	Pathogenic	0.992
LRP5	O75197-1.2	R444G	Pathogenic	0.995
LRP5	O75197-1.2	R444H	Pathogenic	0.951
LRP5	O75197-1.2	R444I	Pathogenic	0.992
LRP5	O75197-1.2	R444K	Pathogenic	0.855
LRP5	O75197-1.2	R444L	Pathogenic	0.978
LRP5	O75197-1.2	R444M	Pathogenic	0.957
LRP5	O75197-1.2	R444N	Pathogenic	0.973
LRP5	O75197-1.2	R444P	Pathogenic	0.99
LRP5	O75197-1.2	R444Q	Pathogenic	0.897
LRP5	O75197-1.2	R444S	Pathogenic	0.985
LRP5	O75197-1.2	R444T	Pathogenic	0.981
LRP5	O75197-1.2	R444V	Pathogenic	0.995
LRP5	O75197-1.2	R444W	Pathogenic	0.988
LRP5	O75197-1.2	R444Y	Pathogenic	0.989
LRP5	O75197-1.2	L445A	Pathogenic	0.973
LRP5	O75197-1.2	L445C	Pathogenic	0.985
LRP5	O75197-1.2	L445D	Pathogenic	0.997
LRP5	O75197-1.2	L445E	Pathogenic	0.993
LRP5	O75197-1.2	L445F	Pathogenic	0.976
LRP5	O75197-1.2	L445G	Pathogenic	0.999
LRP5	O75197-1.2	L445H	Pathogenic	0.997
LRP5	O75197-1.2	L445I	Pathogenic	0.814
LRP5	O75197-1.2	L445K	Pathogenic	0.973
LRP5	O75197-1.2	L445M	Pathogenic	0.76
LRP5	O75197-1.2	L445N	Pathogenic	0.993
LRP5	O75197-1.2	L445P	Pathogenic	0.998
LRP5	O75197-1.2	L445Q	Pathogenic	0.986
LRP5	O75197-1.2	L445R	Pathogenic	0.972
LRP5	O75197-1.2	L445S	Pathogenic	0.988
LRP5	O75197-1.2	L445T	Pathogenic	0.973
LRP5	O75197-1.2	L445V	Pathogenic	0.902
LRP5	O75197-1.2	L445W	Pathogenic	0.996
LRP5	O75197-1.2	L445Y	Pathogenic	0.985
LRP5	O75197-1.2	N446A	Pathogenic	0.993
LRP5	O75197-1.2	N446C	Pathogenic	0.996
LRP5	O75197-1.2	N446D	Pathogenic	0.915
LRP5	O75197-1.2	N446E	Pathogenic	0.973
LRP5	O75197-1.2	N446F	Pathogenic	0.992
LRP5	O75197-1.2	N446G	Pathogenic	0.954
LRP5	O75197-1.2	N446H	Pathogenic	0.864
LRP5	O75197-1.2	N446I	Pathogenic	0.992
LRP5	O75197-1.2	N446K	Pathogenic	0.962
LRP5	O75197-1.2	N446L	Pathogenic	0.993
LRP5	O75197-1.2	N446M	Pathogenic	0.985
LRP5	O75197-1.2	N446P	Pathogenic	0.991
LRP5	O75197-1.2	N446Q	Pathogenic	0.964
LRP5	O75197-1.2	N446R	Pathogenic	0.961
LRP5	O75197-1.2	N446S	Pathogenic	0.881
LRP5	O75197-1.2	N446T	Pathogenic	0.947
LRP5	O75197-1.2	N446V	Pathogenic	0.995
LRP5	O75197-1.2	N446W	Pathogenic	0.996
LRP5	O75197-1.2	N446Y	Pathogenic	0.988
LRP5	O75197-1.2	G447A	Pathogenic	0.979
LRP5	O75197-1.2	G447C	Pathogenic	0.999
LRP5	O75197-1.2	G447D	Pathogenic	0.989
LRP5	O75197-1.2	G447E	Pathogenic	0.997
LRP5	O75197-1.2	G447F	Pathogenic	0.997
LRP5	O75197-1.2	G447H	Pathogenic	0.998
LRP5	O75197-1.2	G447I	Pathogenic	0.999
LRP5	O75197-1.2	G447K	Pathogenic	0.995
LRP5	O75197-1.2	G447L	Pathogenic	0.999
LRP5	O75197-1.2	G447M	Pathogenic	0.998
LRP5	O75197-1.2	G447N	Pathogenic	0.972
LRP5	O75197-1.2	G447P	Pathogenic	0.997
LRP5	O75197-1.2	G447Q	Pathogenic	0.998
LRP5	O75197-1.2	G447R	Pathogenic	0.995
LRP5	O75197-1.2	G447S	Pathogenic	0.983
LRP5	O75197-1.2	G447T	Pathogenic	0.998
LRP5	O75197-1.2	G447V	Pathogenic	0.998
LRP5	O75197-1.2	G447W	Pathogenic	0.985
LRP5	O75197-1.2	G447Y	Pathogenic	0.998
LRP5	O75197-1.2	T448A	Pathogenic	0.937
LRP5	O75197-1.2	T448C	Pathogenic	0.962
LRP5	O75197-1.2	T448D	Pathogenic	0.951
LRP5	O75197-1.2	T448E	Pathogenic	0.956
LRP5	O75197-1.2	T448F	Pathogenic	0.973
LRP5	O75197-1.2	T448G	Pathogenic	0.991
LRP5	O75197-1.2	T448H	Pathogenic	0.992
LRP5	O75197-1.2	T448I	Pathogenic	0.922
LRP5	O75197-1.2	T448K	Pathogenic	0.938
LRP5	O75197-1.2	T448L	Pathogenic	0.928
LRP5	O75197-1.2	T448M	Pathogenic	0.951
LRP5	O75197-1.2	T448N	Pathogenic	0.882
LRP5	O75197-1.2	T448P	Pathogenic	0.97
LRP5	O75197-1.2	T448Q	Pathogenic	0.969
LRP5	O75197-1.2	T448R	Pathogenic	0.936
LRP5	O75197-1.2	T448S	Pathogenic	0.799
LRP5	O75197-1.2	T448V	Pathogenic	0.871
LRP5	O75197-1.2	T448W	Pathogenic	0.957
LRP5	O75197-1.2	T448Y	Pathogenic	0.987
LRP5	O75197-1.2	S449A	Neutral	0.066
LRP5	O75197-1.2	S449C	Neutral	0.262
LRP5	O75197-1.2	S449D	Neutral	0.13
LRP5	O75197-1.2	S449E	Neutral	0.14
LRP5	O75197-1.2	S449F	Neutral	0.327
LRP5	O75197-1.2	S449G	Neutral	0.216
LRP5	O75197-1.2	S449H	Neutral	0.419
LRP5	O75197-1.2	S449I	Neutral	0.328
LRP5	O75197-1.2	S449K	Neutral	0.103
LRP5	O75197-1.2	S449L	Neutral	0.348
LRP5	O75197-1.2	S449M	Neutral	0.211
LRP5	O75197-1.2	S449N	Neutral	0.054
LRP5	O75197-1.2	S449P	Neutral	0.309
LRP5	O75197-1.2	S449Q	Neutral	0.191
LRP5	O75197-1.2	S449R	Neutral	0.252
LRP5	O75197-1.2	S449T	Neutral	0.068
LRP5	O75197-1.2	S449V	Neutral	0.459
LRP5	O75197-1.2	S449W	Neutral	0.483
LRP5	O75197-1.2	S449Y	Pathogenic	0.502
LRP5	O75197-1.2	R450A	Pathogenic	0.983
LRP5	O75197-1.2	R450C	Pathogenic	0.997
LRP5	O75197-1.2	R450D	Pathogenic	0.998
LRP5	O75197-1.2	R450E	Pathogenic	0.98
LRP5	O75197-1.2	R450F	Pathogenic	0.994
LRP5	O75197-1.2	R450G	Pathogenic	0.996
LRP5	O75197-1.2	R450H	Pathogenic	0.961
LRP5	O75197-1.2	R450I	Pathogenic	0.994
LRP5	O75197-1.2	R450K	Pathogenic	0.881
LRP5	O75197-1.2	R450L	Pathogenic	0.983
LRP5	O75197-1.2	R450M	Pathogenic	0.966
LRP5	O75197-1.2	R450N	Pathogenic	0.979
LRP5	O75197-1.2	R450P	Pathogenic	0.992
LRP5	O75197-1.2	R450Q	Pathogenic	0.916
LRP5	O75197-1.2	R450S	Pathogenic	0.988
LRP5	O75197-1.2	R450T	Pathogenic	0.985
LRP5	O75197-1.2	R450V	Pathogenic	0.996
LRP5	O75197-1.2	R450W	Pathogenic	0.991
LRP5	O75197-1.2	R450Y	Pathogenic	0.991
LRP5	O75197-1.2	K451A	Pathogenic	0.937
LRP5	O75197-1.2	K451C	Pathogenic	0.987
LRP5	O75197-1.2	K451D	Pathogenic	0.976
LRP5	O75197-1.2	K451E	Pathogenic	0.801
LRP5	O75197-1.2	K451F	Pathogenic	0.976
LRP5	O75197-1.2	K451G	Pathogenic	0.983
LRP5	O75197-1.2	K451H	Pathogenic	0.95
LRP5	O75197-1.2	K451I	Pathogenic	0.976
LRP5	O75197-1.2	K451L	Pathogenic	0.935
LRP5	O75197-1.2	K451M	Pathogenic	0.878
LRP5	O75197-1.2	K451N	Pathogenic	0.921
LRP5	O75197-1.2	K451P	Pathogenic	0.915
LRP5	O75197-1.2	K451Q	Pathogenic	0.737
LRP5	O75197-1.2	K451R	Pathogenic	0.647
LRP5	O75197-1.2	K451S	Pathogenic	0.871
LRP5	O75197-1.2	K451T	Pathogenic	0.942
LRP5	O75197-1.2	K451V	Pathogenic	0.956
LRP5	O75197-1.2	K451W	Pathogenic	0.963
LRP5	O75197-1.2	K451Y	Pathogenic	0.966
LRP5	O75197-1.2	I452A	Pathogenic	0.896
LRP5	O75197-1.2	I452C	Pathogenic	0.942
LRP5	O75197-1.2	I452D	Pathogenic	0.969
LRP5	O75197-1.2	I452E	Pathogenic	0.973
LRP5	O75197-1.2	I452F	Pathogenic	0.92
LRP5	O75197-1.2	I452G	Pathogenic	0.994
LRP5	O75197-1.2	I452H	Pathogenic	0.987
LRP5	O75197-1.2	I452K	Pathogenic	0.964
LRP5	O75197-1.2	I452L	Pathogenic	0.537
LRP5	O75197-1.2	I452M	Pathogenic	0.699
LRP5	O75197-1.2	I452N	Pathogenic	0.974
LRP5	O75197-1.2	I452P	Pathogenic	0.992
LRP5	O75197-1.2	I452Q	Pathogenic	0.982
LRP5	O75197-1.2	I452R	Pathogenic	0.963
LRP5	O75197-1.2	I452S	Pathogenic	0.951
LRP5	O75197-1.2	I452T	Pathogenic	0.895
LRP5	O75197-1.2	I452V	Neutral	0.194
LRP5	O75197-1.2	I452W	Pathogenic	0.995
LRP5	O75197-1.2	I452Y	Pathogenic	0.943
LRP5	O75197-1.2	L453A	Pathogenic	0.973
LRP5	O75197-1.2	L453C	Pathogenic	0.985
LRP5	O75197-1.2	L453D	Pathogenic	0.998
LRP5	O75197-1.2	L453E	Pathogenic	0.993
LRP5	O75197-1.2	L453F	Pathogenic	0.976
LRP5	O75197-1.2	L453G	Pathogenic	0.999
LRP5	O75197-1.2	L453H	Pathogenic	0.997
LRP5	O75197-1.2	L453I	Pathogenic	0.816
LRP5	O75197-1.2	L453K	Pathogenic	0.974
LRP5	O75197-1.2	L453M	Pathogenic	0.761
LRP5	O75197-1.2	L453N	Pathogenic	0.994
LRP5	O75197-1.2	L453P	Pathogenic	0.998
LRP5	O75197-1.2	L453Q	Pathogenic	0.987
LRP5	O75197-1.2	L453R	Pathogenic	0.973
LRP5	O75197-1.2	L453S	Pathogenic	0.988
LRP5	O75197-1.2	L453T	Pathogenic	0.973
LRP5	O75197-1.2	L453V	Pathogenic	0.903
LRP5	O75197-1.2	L453W	Pathogenic	0.996
LRP5	O75197-1.2	L453Y	Pathogenic	0.986
LRP5	O75197-1.2	V454A	Neutral	0.331
LRP5	O75197-1.2	V454C	Pathogenic	0.74
LRP5	O75197-1.2	V454D	Pathogenic	0.847
LRP5	O75197-1.2	V454E	Pathogenic	0.675
LRP5	O75197-1.2	V454F	Pathogenic	0.674
LRP5	O75197-1.2	V454G	Pathogenic	0.911
LRP5	O75197-1.2	V454H	Pathogenic	0.925
LRP5	O75197-1.2	V454I	Neutral	0.024
LRP5	O75197-1.2	V454K	Pathogenic	0.593
LRP5	O75197-1.2	V454L	Neutral	0.197
LRP5	O75197-1.2	V454M	Neutral	0.272
LRP5	O75197-1.2	V454N	Pathogenic	0.866
LRP5	O75197-1.2	V454P	Pathogenic	0.873
LRP5	O75197-1.2	V454Q	Pathogenic	0.75
LRP5	O75197-1.2	V454R	Pathogenic	0.811
LRP5	O75197-1.2	V454S	Pathogenic	0.773
LRP5	O75197-1.2	V454T	Neutral	0.33
LRP5	O75197-1.2	V454W	Pathogenic	0.924
LRP5	O75197-1.2	V454Y	Pathogenic	0.73
LRP5	O75197-1.2	S455A	Pathogenic	0.588
LRP5	O75197-1.2	S455C	Pathogenic	0.877
LRP5	O75197-1.2	S455D	Pathogenic	0.751
LRP5	O75197-1.2	S455E	Pathogenic	0.767
LRP5	O75197-1.2	S455F	Pathogenic	0.907
LRP5	O75197-1.2	S455G	Pathogenic	0.847
LRP5	O75197-1.2	S455H	Pathogenic	0.936
LRP5	O75197-1.2	S455I	Pathogenic	0.908
LRP5	O75197-1.2	S455K	Pathogenic	0.697
LRP5	O75197-1.2	S455L	Pathogenic	0.915
LRP5	O75197-1.2	S455M	Pathogenic	0.843
LRP5	O75197-1.2	S455N	Pathogenic	0.533
LRP5	O75197-1.2	S455P	Pathogenic	0.9
LRP5	O75197-1.2	S455Q	Pathogenic	0.826
LRP5	O75197-1.2	S455R	Pathogenic	0.871
LRP5	O75197-1.2	S455T	Pathogenic	0.594
LRP5	O75197-1.2	S455V	Pathogenic	0.945
LRP5	O75197-1.2	S455W	Pathogenic	0.95
LRP5	O75197-1.2	S455Y	Pathogenic	0.953
LRP5	O75197-1.2	E456A	Pathogenic	0.981
LRP5	O75197-1.2	E456C	Pathogenic	0.999
LRP5	O75197-1.2	E456D	Pathogenic	0.795
LRP5	O75197-1.2	E456F	Pathogenic	0.992
LRP5	O75197-1.2	E456G	Pathogenic	0.995
LRP5	O75197-1.2	E456H	Pathogenic	0.954
LRP5	O75197-1.2	E456I	Pathogenic	0.992
LRP5	O75197-1.2	E456K	Pathogenic	0.905
LRP5	O75197-1.2	E456L	Pathogenic	0.993
LRP5	O75197-1.2	E456M	Pathogenic	0.986
LRP5	O75197-1.2	E456N	Pathogenic	0.975
LRP5	O75197-1.2	E456P	Pathogenic	0.973
LRP5	O75197-1.2	E456Q	Pathogenic	0.754
LRP5	O75197-1.2	E456R	Pathogenic	0.966
LRP5	O75197-1.2	E456S	Pathogenic	0.958
LRP5	O75197-1.2	E456T	Pathogenic	0.982
LRP5	O75197-1.2	E456V	Pathogenic	0.986
LRP5	O75197-1.2	E456W	Pathogenic	0.988
LRP5	O75197-1.2	E456Y	Pathogenic	0.989
LRP5	O75197-1.2	D457A	Pathogenic	0.812
LRP5	O75197-1.2	D457C	Pathogenic	0.881
LRP5	O75197-1.2	D457E	Neutral	0.106
LRP5	O75197-1.2	D457F	Pathogenic	0.772
LRP5	O75197-1.2	D457G	Pathogenic	0.644
LRP5	O75197-1.2	D457H	Pathogenic	0.623
LRP5	O75197-1.2	D457I	Pathogenic	0.772
LRP5	O75197-1.2	D457K	Pathogenic	0.747
LRP5	O75197-1.2	D457L	Pathogenic	0.919
LRP5	O75197-1.2	D457M	Pathogenic	0.85
LRP5	O75197-1.2	D457N	Neutral	0.262
LRP5	O75197-1.2	D457P	Pathogenic	0.505
LRP5	O75197-1.2	D457Q	Neutral	0.428
LRP5	O75197-1.2	D457R	Pathogenic	0.897
LRP5	O75197-1.2	D457S	Neutral	0.39
LRP5	O75197-1.2	D457T	Pathogenic	0.606
LRP5	O75197-1.2	D457V	Pathogenic	0.855
LRP5	O75197-1.2	D457W	Pathogenic	0.867
LRP5	O75197-1.2	D457Y	Pathogenic	0.875
LRP5	O75197-1.2	L458A	Pathogenic	0.965
LRP5	O75197-1.2	L458C	Pathogenic	0.981
LRP5	O75197-1.2	L458D	Pathogenic	0.997
LRP5	O75197-1.2	L458E	Pathogenic	0.992
LRP5	O75197-1.2	L458F	Pathogenic	0.969
LRP5	O75197-1.2	L458G	Pathogenic	0.998
LRP5	O75197-1.2	L458H	Pathogenic	0.996
LRP5	O75197-1.2	L458I	Pathogenic	0.775
LRP5	O75197-1.2	L458K	Pathogenic	0.966
LRP5	O75197-1.2	L458M	Pathogenic	0.713
LRP5	O75197-1.2	L458N	Pathogenic	0.992
LRP5	O75197-1.2	L458P	Pathogenic	0.997
LRP5	O75197-1.2	L458Q	Pathogenic	0.983
LRP5	O75197-1.2	L458R	Pathogenic	0.965
LRP5	O75197-1.2	L458S	Pathogenic	0.984
LRP5	O75197-1.2	L458T	Pathogenic	0.965
LRP5	O75197-1.2	L458V	Pathogenic	0.878
LRP5	O75197-1.2	L458W	Pathogenic	0.995
LRP5	O75197-1.2	L458Y	Pathogenic	0.982
LRP5	O75197-1.2	D459A	Pathogenic	0.505
LRP5	O75197-1.2	D459C	Pathogenic	0.636
LRP5	O75197-1.2	D459E	Neutral	0.027
LRP5	O75197-1.2	D459F	Neutral	0.444
LRP5	O75197-1.2	D459G	Neutral	0.3
LRP5	O75197-1.2	D459H	Neutral	0.281
LRP5	O75197-1.2	D459I	Neutral	0.445
LRP5	O75197-1.2	D459K	Neutral	0.411
LRP5	O75197-1.2	D459L	Pathogenic	0.728
LRP5	O75197-1.2	D459M	Pathogenic	0.572
LRP5	O75197-1.2	D459N	Neutral	0.078
LRP5	O75197-1.2	D459P	Neutral	0.194
LRP5	O75197-1.2	D459Q	Neutral	0.15
LRP5	O75197-1.2	D459R	Pathogenic	0.672
LRP5	O75197-1.2	D459S	Neutral	0.131
LRP5	O75197-1.2	D459T	Neutral	0.266
LRP5	O75197-1.2	D459V	Pathogenic	0.583
LRP5	O75197-1.2	D459W	Pathogenic	0.606
LRP5	O75197-1.2	D459Y	Pathogenic	0.624
LRP5	O75197-1.2	E460A	Pathogenic	0.988
LRP5	O75197-1.2	E460C	Pathogenic	0.999
LRP5	O75197-1.2	E460D	Pathogenic	0.859
LRP5	O75197-1.2	E460F	Pathogenic	0.995
LRP5	O75197-1.2	E460G	Pathogenic	0.997
LRP5	O75197-1.2	E460H	Pathogenic	0.97
LRP5	O75197-1.2	E460I	Pathogenic	0.995
LRP5	O75197-1.2	E460K	Pathogenic	0.937
LRP5	O75197-1.2	E460L	Pathogenic	0.995
LRP5	O75197-1.2	E460M	Pathogenic	0.991
LRP5	O75197-1.2	E460N	Pathogenic	0.984
LRP5	O75197-1.2	E460P	Pathogenic	0.983
LRP5	O75197-1.2	E460Q	Pathogenic	0.828
LRP5	O75197-1.2	E460R	Pathogenic	0.978
LRP5	O75197-1.2	E460S	Pathogenic	0.973
LRP5	O75197-1.2	E460T	Pathogenic	0.989
LRP5	O75197-1.2	E460V	Pathogenic	0.991
LRP5	O75197-1.2	E460W	Pathogenic	0.992
LRP5	O75197-1.2	E460Y	Pathogenic	0.993
LRP5	O75197-1.2	P461A	Pathogenic	0.993
LRP5	O75197-1.2	P461C	Pathogenic	0.999
LRP5	O75197-1.2	P461D	Pathogenic	0.983
LRP5	O75197-1.2	P461E	Pathogenic	0.985
LRP5	O75197-1.2	P461F	Pathogenic	1.0
LRP5	O75197-1.2	P461G	Pathogenic	0.997
LRP5	O75197-1.2	P461H	Pathogenic	0.997
LRP5	O75197-1.2	P461I	Pathogenic	0.999
LRP5	O75197-1.2	P461K	Pathogenic	0.978
LRP5	O75197-1.2	P461L	Pathogenic	0.999
LRP5	O75197-1.2	P461M	Pathogenic	0.998
LRP5	O75197-1.2	P461N	Pathogenic	0.995
LRP5	O75197-1.2	P461Q	Pathogenic	0.989
LRP5	O75197-1.2	P461R	Pathogenic	0.992
LRP5	O75197-1.2	P461S	Pathogenic	0.991
LRP5	O75197-1.2	P461T	Pathogenic	0.993
LRP5	O75197-1.2	P461V	Pathogenic	0.998
LRP5	O75197-1.2	P461W	Pathogenic	0.999
LRP5	O75197-1.2	P461Y	Pathogenic	0.999
LRP5	O75197-1.2	R462A	Pathogenic	0.983
LRP5	O75197-1.2	R462C	Pathogenic	0.997
LRP5	O75197-1.2	R462D	Pathogenic	0.998
LRP5	O75197-1.2	R462E	Pathogenic	0.98
LRP5	O75197-1.2	R462F	Pathogenic	0.994
LRP5	O75197-1.2	R462G	Pathogenic	0.996
LRP5	O75197-1.2	R462H	Pathogenic	0.961
LRP5	O75197-1.2	R462I	Pathogenic	0.994
LRP5	O75197-1.2	R462K	Pathogenic	0.881
LRP5	O75197-1.2	R462L	Pathogenic	0.983
LRP5	O75197-1.2	R462M	Pathogenic	0.966
LRP5	O75197-1.2	R462N	Pathogenic	0.979
LRP5	O75197-1.2	R462P	Pathogenic	0.992
LRP5	O75197-1.2	R462Q	Pathogenic	0.916
LRP5	O75197-1.2	R462S	Pathogenic	0.988
LRP5	O75197-1.2	R462T	Pathogenic	0.985
LRP5	O75197-1.2	R462V	Pathogenic	0.996
LRP5	O75197-1.2	R462W	Pathogenic	0.991
LRP5	O75197-1.2	R462Y	Pathogenic	0.991
LRP5	O75197-1.2	A463C	Pathogenic	0.975
LRP5	O75197-1.2	A463D	Pathogenic	0.996
LRP5	O75197-1.2	A463E	Pathogenic	0.989
LRP5	O75197-1.2	A463F	Pathogenic	0.994
LRP5	O75197-1.2	A463G	Pathogenic	0.982
LRP5	O75197-1.2	A463H	Pathogenic	0.998
LRP5	O75197-1.2	A463I	Pathogenic	0.982
LRP5	O75197-1.2	A463K	Pathogenic	0.984
LRP5	O75197-1.2	A463L	Pathogenic	0.983
LRP5	O75197-1.2	A463M	Pathogenic	0.989
LRP5	O75197-1.2	A463N	Pathogenic	0.997
LRP5	O75197-1.2	A463P	Pathogenic	0.993
LRP5	O75197-1.2	A463Q	Pathogenic	0.992
LRP5	O75197-1.2	A463R	Pathogenic	0.984
LRP5	O75197-1.2	A463S	Pathogenic	0.946
LRP5	O75197-1.2	A463T	Pathogenic	0.985
LRP5	O75197-1.2	A463V	Pathogenic	0.968
LRP5	O75197-1.2	A463W	Pathogenic	0.997
LRP5	O75197-1.2	A463Y	Pathogenic	0.997
LRP5	O75197-1.2	I464A	Pathogenic	0.97
LRP5	O75197-1.2	I464C	Pathogenic	0.984
LRP5	O75197-1.2	I464D	Pathogenic	0.992
LRP5	O75197-1.2	I464E	Pathogenic	0.993
LRP5	O75197-1.2	I464F	Pathogenic	0.977
LRP5	O75197-1.2	I464G	Pathogenic	0.999
LRP5	O75197-1.2	I464H	Pathogenic	0.996
LRP5	O75197-1.2	I464K	Pathogenic	0.99
LRP5	O75197-1.2	I464L	Pathogenic	0.814
LRP5	O75197-1.2	I464M	Pathogenic	0.898
LRP5	O75197-1.2	I464N	Pathogenic	0.993
LRP5	O75197-1.2	I464P	Pathogenic	0.998
LRP5	O75197-1.2	I464Q	Pathogenic	0.995
LRP5	O75197-1.2	I464R	Pathogenic	0.99
LRP5	O75197-1.2	I464S	Pathogenic	0.987
LRP5	O75197-1.2	I464T	Pathogenic	0.97
LRP5	O75197-1.2	I464V	Neutral	0.476
LRP5	O75197-1.2	I464W	Pathogenic	0.999
LRP5	O75197-1.2	I464Y	Pathogenic	0.984
LRP5	O75197-1.2	A465C	Neutral	0.149
LRP5	O75197-1.2	A465D	Pathogenic	0.528
LRP5	O75197-1.2	A465E	Neutral	0.286
LRP5	O75197-1.2	A465F	Neutral	0.42
LRP5	O75197-1.2	A465G	Neutral	0.195
LRP5	O75197-1.2	A465H	Pathogenic	0.705
LRP5	O75197-1.2	A465I	Neutral	0.193
LRP5	O75197-1.2	A465K	Neutral	0.219
LRP5	O75197-1.2	A465L	Neutral	0.208
LRP5	O75197-1.2	A465M	Neutral	0.285
LRP5	O75197-1.2	A465N	Pathogenic	0.563
LRP5	O75197-1.2	A465P	Neutral	0.4
LRP5	O75197-1.2	A465Q	Neutral	0.366
LRP5	O75197-1.2	A465R	Neutral	0.214
LRP5	O75197-1.2	A465S	Neutral	0.073
LRP5	O75197-1.2	A465T	Neutral	0.231
LRP5	O75197-1.2	A465V	Neutral	0.121
LRP5	O75197-1.2	A465W	Pathogenic	0.583
LRP5	O75197-1.2	A465Y	Pathogenic	0.601
LRP5	O75197-1.2	L466A	Pathogenic	0.907
LRP5	O75197-1.2	L466C	Pathogenic	0.948
LRP5	O75197-1.2	L466D	Pathogenic	0.991
LRP5	O75197-1.2	L466E	Pathogenic	0.976
LRP5	O75197-1.2	L466F	Pathogenic	0.917
LRP5	O75197-1.2	L466G	Pathogenic	0.995
LRP5	O75197-1.2	L466H	Pathogenic	0.988
LRP5	O75197-1.2	L466I	Pathogenic	0.545
LRP5	O75197-1.2	L466K	Pathogenic	0.909
LRP5	O75197-1.2	L466M	Neutral	0.463
LRP5	O75197-1.2	L466N	Pathogenic	0.977
LRP5	O75197-1.2	L466P	Pathogenic	0.993
LRP5	O75197-1.2	L466Q	Pathogenic	0.952
LRP5	O75197-1.2	L466R	Pathogenic	0.906
LRP5	O75197-1.2	L466S	Pathogenic	0.956
LRP5	O75197-1.2	L466T	Pathogenic	0.906
LRP5	O75197-1.2	L466V	Pathogenic	0.715
LRP5	O75197-1.2	L466W	Pathogenic	0.985
LRP5	O75197-1.2	L466Y	Pathogenic	0.949
LRP5	O75197-1.2	H467A	Pathogenic	0.719
LRP5	O75197-1.2	H467C	Pathogenic	0.814
LRP5	O75197-1.2	H467D	Neutral	0.313
LRP5	O75197-1.2	H467E	Neutral	0.148
LRP5	O75197-1.2	H467F	Neutral	0.191
LRP5	O75197-1.2	H467G	Pathogenic	0.721
LRP5	O75197-1.2	H467I	Pathogenic	0.687
LRP5	O75197-1.2	H467K	Neutral	0.276
LRP5	O75197-1.2	H467L	Pathogenic	0.706
LRP5	O75197-1.2	H467M	Pathogenic	0.546
LRP5	O75197-1.2	H467N	Neutral	0.055
LRP5	O75197-1.2	H467P	Pathogenic	0.648
LRP5	O75197-1.2	H467Q	Neutral	0.203
LRP5	O75197-1.2	H467R	Neutral	0.108
LRP5	O75197-1.2	H467S	Neutral	0.461
LRP5	O75197-1.2	H467T	Pathogenic	0.736
LRP5	O75197-1.2	H467V	Pathogenic	0.786
LRP5	O75197-1.2	H467W	Neutral	0.312
LRP5	O75197-1.2	H467Y	Neutral	0.017
LRP5	O75197-1.2	P468A	Pathogenic	0.993
LRP5	O75197-1.2	P468C	Pathogenic	0.999
LRP5	O75197-1.2	P468D	Pathogenic	0.983
LRP5	O75197-1.2	P468E	Pathogenic	0.985
LRP5	O75197-1.2	P468F	Pathogenic	1.0
LRP5	O75197-1.2	P468G	Pathogenic	0.997
LRP5	O75197-1.2	P468H	Pathogenic	0.997
LRP5	O75197-1.2	P468I	Pathogenic	0.999
LRP5	O75197-1.2	P468K	Pathogenic	0.978
LRP5	O75197-1.2	P468L	Pathogenic	0.999
LRP5	O75197-1.2	P468M	Pathogenic	0.998
LRP5	O75197-1.2	P468N	Pathogenic	0.995
LRP5	O75197-1.2	P468Q	Pathogenic	0.989
LRP5	O75197-1.2	P468R	Pathogenic	0.992
LRP5	O75197-1.2	P468S	Pathogenic	0.991
LRP5	O75197-1.2	P468T	Pathogenic	0.993
LRP5	O75197-1.2	P468V	Pathogenic	0.998
LRP5	O75197-1.2	P468W	Pathogenic	0.999
LRP5	O75197-1.2	P468Y	Pathogenic	0.999
LRP5	O75197-1.2	V469A	Neutral	0.05
LRP5	O75197-1.2	V469C	Neutral	0.231
LRP5	O75197-1.2	V469D	Neutral	0.368
LRP5	O75197-1.2	V469E	Neutral	0.18
LRP5	O75197-1.2	V469F	Neutral	0.179
LRP5	O75197-1.2	V469G	Pathogenic	0.52
LRP5	O75197-1.2	V469H	Pathogenic	0.567
LRP5	O75197-1.2	V469I	Neutral	0.003
LRP5	O75197-1.2	V469K	Neutral	0.133
LRP5	O75197-1.2	V469L	Neutral	0.025
LRP5	O75197-1.2	V469M	Neutral	0.038
LRP5	O75197-1.2	V469N	Neutral	0.406
LRP5	O75197-1.2	V469P	Neutral	0.42
LRP5	O75197-1.2	V469Q	Neutral	0.24
LRP5	O75197-1.2	V469R	Neutral	0.311
LRP5	O75197-1.2	V469S	Neutral	0.264
LRP5	O75197-1.2	V469T	Neutral	0.049
LRP5	O75197-1.2	V469W	Pathogenic	0.56
LRP5	O75197-1.2	V469Y	Neutral	0.222
LRP5	O75197-1.2	M470A	Neutral	0.039
LRP5	O75197-1.2	M470C	Neutral	0.071
LRP5	O75197-1.2	M470D	Neutral	0.13
LRP5	O75197-1.2	M470E	Neutral	0.054
LRP5	O75197-1.2	M470F	Neutral	0.02
LRP5	O75197-1.2	M470G	Neutral	0.217
LRP5	O75197-1.2	M470H	Neutral	0.103
LRP5	O75197-1.2	M470I	Neutral	0.007
LRP5	O75197-1.2	M470K	Neutral	0.014
LRP5	O75197-1.2	M470L	Neutral	0.002
LRP5	O75197-1.2	M470N	Neutral	0.054
LRP5	O75197-1.2	M470P	Neutral	0.157
LRP5	O75197-1.2	M470Q	Neutral	0.009
LRP5	O75197-1.2	M470R	Neutral	0.013
LRP5	O75197-1.2	M470S	Neutral	0.029
LRP5	O75197-1.2	M470T	Neutral	0.039
LRP5	O75197-1.2	M470V	Neutral	0.01
LRP5	O75197-1.2	M470W	Neutral	0.037
LRP5	O75197-1.2	M470Y	Neutral	0.072
LRP5	O75197-1.2	G471A	Pathogenic	0.98
LRP5	O75197-1.2	G471C	Pathogenic	0.999
LRP5	O75197-1.2	G471D	Pathogenic	0.99
LRP5	O75197-1.2	G471E	Pathogenic	0.997
LRP5	O75197-1.2	G471F	Pathogenic	0.997
LRP5	O75197-1.2	G471H	Pathogenic	0.998
LRP5	O75197-1.2	G471I	Pathogenic	0.999
LRP5	O75197-1.2	G471K	Pathogenic	0.995
LRP5	O75197-1.2	G471L	Pathogenic	0.999
LRP5	O75197-1.2	G471M	Pathogenic	0.998
LRP5	O75197-1.2	G471N	Pathogenic	0.973
LRP5	O75197-1.2	G471P	Pathogenic	0.997
LRP5	O75197-1.2	G471Q	Pathogenic	0.998
LRP5	O75197-1.2	G471R	Pathogenic	0.995
LRP5	O75197-1.2	G471S	Pathogenic	0.984
LRP5	O75197-1.2	G471T	Pathogenic	0.998
LRP5	O75197-1.2	G471V	Pathogenic	0.998
LRP5	O75197-1.2	G471W	Pathogenic	0.986
LRP5	O75197-1.2	G471Y	Pathogenic	0.999
LRP5	O75197-1.2	L472A	Neutral	0.103
LRP5	O75197-1.2	L472C	Neutral	0.179
LRP5	O75197-1.2	L472D	Pathogenic	0.563
LRP5	O75197-1.2	L472E	Neutral	0.329
LRP5	O75197-1.2	L472F	Neutral	0.116
LRP5	O75197-1.2	L472G	Pathogenic	0.705
LRP5	O75197-1.2	L472H	Neutral	0.498
LRP5	O75197-1.2	L472I	Neutral	0.014
LRP5	O75197-1.2	L472K	Neutral	0.106
LRP5	O75197-1.2	L472M	Neutral	0.01
LRP5	O75197-1.2	L472N	Neutral	0.332
LRP5	O75197-1.2	L472P	Pathogenic	0.615
LRP5	O75197-1.2	L472Q	Neutral	0.191
LRP5	O75197-1.2	L472R	Neutral	0.103
LRP5	O75197-1.2	L472S	Neutral	0.207
LRP5	O75197-1.2	L472T	Neutral	0.103
LRP5	O75197-1.2	L472V	Neutral	0.029
LRP5	O75197-1.2	L472W	Neutral	0.434
LRP5	O75197-1.2	L472Y	Neutral	0.181
LRP5	O75197-1.2	M473A	Pathogenic	0.996
LRP5	O75197-1.2	M473C	Pathogenic	0.998
LRP5	O75197-1.2	M473D	Pathogenic	0.999
LRP5	O75197-1.2	M473E	Pathogenic	0.997
LRP5	O75197-1.2	M473F	Pathogenic	0.991
LRP5	O75197-1.2	M473G	Pathogenic	0.999
LRP5	O75197-1.2	M473H	Pathogenic	0.998
LRP5	O75197-1.2	M473I	Pathogenic	0.974
LRP5	O75197-1.2	M473K	Pathogenic	0.988
LRP5	O75197-1.2	M473L	Pathogenic	0.932
LRP5	O75197-1.2	M473N	Pathogenic	0.997
LRP5	O75197-1.2	M473P	Pathogenic	0.999
LRP5	O75197-1.2	M473Q	Pathogenic	0.981
LRP5	O75197-1.2	M473R	Pathogenic	0.987
LRP5	O75197-1.2	M473S	Pathogenic	0.994
LRP5	O75197-1.2	M473T	Pathogenic	0.996
LRP5	O75197-1.2	M473V	Pathogenic	0.984
LRP5	O75197-1.2	M473W	Pathogenic	0.996
LRP5	O75197-1.2	M473Y	Pathogenic	0.998
LRP5	O75197-1.2	Y474A	Pathogenic	0.994
LRP5	O75197-1.2	Y474C	Pathogenic	0.997
LRP5	O75197-1.2	Y474D	Pathogenic	0.995
LRP5	O75197-1.2	Y474E	Pathogenic	0.987
LRP5	O75197-1.2	Y474F	Neutral	0.384
LRP5	O75197-1.2	Y474G	Pathogenic	0.997
LRP5	O75197-1.2	Y474H	Pathogenic	0.649
LRP5	O75197-1.2	Y474I	Pathogenic	0.981
LRP5	O75197-1.2	Y474K	Pathogenic	0.984
LRP5	O75197-1.2	Y474L	Pathogenic	0.983
LRP5	O75197-1.2	Y474M	Pathogenic	0.989
LRP5	O75197-1.2	Y474N	Pathogenic	0.988
LRP5	O75197-1.2	Y474P	Pathogenic	0.999
LRP5	O75197-1.2	Y474Q	Pathogenic	0.974
LRP5	O75197-1.2	Y474R	Pathogenic	0.983
LRP5	O75197-1.2	Y474S	Pathogenic	0.992
LRP5	O75197-1.2	Y474T	Pathogenic	0.994
LRP5	O75197-1.2	Y474V	Pathogenic	0.988
LRP5	O75197-1.2	Y474W	Pathogenic	0.55
LRP5	O75197-1.2	W475A	Pathogenic	0.999
LRP5	O75197-1.2	W475C	Pathogenic	0.999
LRP5	O75197-1.2	W475D	Pathogenic	0.999
LRP5	O75197-1.2	W475E	Pathogenic	0.998
LRP5	O75197-1.2	W475F	Pathogenic	0.986
LRP5	O75197-1.2	W475G	Pathogenic	0.997
LRP5	O75197-1.2	W475H	Pathogenic	0.998
LRP5	O75197-1.2	W475I	Pathogenic	1.0
LRP5	O75197-1.2	W475K	Pathogenic	0.998
LRP5	O75197-1.2	W475L	Pathogenic	0.999
LRP5	O75197-1.2	W475M	Pathogenic	0.997
LRP5	O75197-1.2	W475N	Pathogenic	0.999
LRP5	O75197-1.2	W475P	Pathogenic	1.0
LRP5	O75197-1.2	W475Q	Pathogenic	0.997
LRP5	O75197-1.2	W475R	Pathogenic	0.998
LRP5	O75197-1.2	W475S	Pathogenic	0.999
LRP5	O75197-1.2	W475T	Pathogenic	0.998
LRP5	O75197-1.2	W475V	Pathogenic	1.0
LRP5	O75197-1.2	W475Y	Pathogenic	0.915
LRP5	O75197-1.2	T476A	Pathogenic	0.984
LRP5	O75197-1.2	T476C	Pathogenic	0.99
LRP5	O75197-1.2	T476D	Pathogenic	0.988
LRP5	O75197-1.2	T476E	Pathogenic	0.989
LRP5	O75197-1.2	T476F	Pathogenic	0.993
LRP5	O75197-1.2	T476G	Pathogenic	0.998
LRP5	O75197-1.2	T476H	Pathogenic	0.998
LRP5	O75197-1.2	T476I	Pathogenic	0.979
LRP5	O75197-1.2	T476K	Pathogenic	0.984
LRP5	O75197-1.2	T476L	Pathogenic	0.981
LRP5	O75197-1.2	T476M	Pathogenic	0.988
LRP5	O75197-1.2	T476N	Pathogenic	0.968
LRP5	O75197-1.2	T476P	Pathogenic	0.992
LRP5	O75197-1.2	T476Q	Pathogenic	0.992
LRP5	O75197-1.2	T476R	Pathogenic	0.983
LRP5	O75197-1.2	T476S	Pathogenic	0.941
LRP5	O75197-1.2	T476V	Pathogenic	0.965
LRP5	O75197-1.2	T476W	Pathogenic	0.989
LRP5	O75197-1.2	T476Y	Pathogenic	0.997
LRP5	O75197-1.2	D477A	Pathogenic	0.995
LRP5	O75197-1.2	D477C	Pathogenic	0.997
LRP5	O75197-1.2	D477E	Pathogenic	0.858
LRP5	O75197-1.2	D477F	Pathogenic	0.994
LRP5	O75197-1.2	D477G	Pathogenic	0.989
LRP5	O75197-1.2	D477H	Pathogenic	0.988
LRP5	O75197-1.2	D477I	Pathogenic	0.994
LRP5	O75197-1.2	D477K	Pathogenic	0.993
LRP5	O75197-1.2	D477L	Pathogenic	0.998
LRP5	O75197-1.2	D477M	Pathogenic	0.997
LRP5	O75197-1.2	D477N	Pathogenic	0.948
LRP5	O75197-1.2	D477P	Pathogenic	0.981
LRP5	O75197-1.2	D477Q	Pathogenic	0.975
LRP5	O75197-1.2	D477R	Pathogenic	0.998
LRP5	O75197-1.2	D477S	Pathogenic	0.97
LRP5	O75197-1.2	D477T	Pathogenic	0.987
LRP5	O75197-1.2	D477V	Pathogenic	0.997
LRP5	O75197-1.2	D477W	Pathogenic	0.997
LRP5	O75197-1.2	D477Y	Pathogenic	0.997
LRP5	O75197-1.2	W478A	Pathogenic	0.999
LRP5	O75197-1.2	W478C	Pathogenic	0.999
LRP5	O75197-1.2	W478D	Pathogenic	0.999
LRP5	O75197-1.2	W478E	Pathogenic	0.998
LRP5	O75197-1.2	W478F	Pathogenic	0.986
LRP5	O75197-1.2	W478G	Pathogenic	0.997
LRP5	O75197-1.2	W478H	Pathogenic	0.998
LRP5	O75197-1.2	W478I	Pathogenic	1.0
LRP5	O75197-1.2	W478K	Pathogenic	0.998
LRP5	O75197-1.2	W478L	Pathogenic	0.999
LRP5	O75197-1.2	W478M	Pathogenic	0.997
LRP5	O75197-1.2	W478N	Pathogenic	0.999
LRP5	O75197-1.2	W478P	Pathogenic	1.0
LRP5	O75197-1.2	W478Q	Pathogenic	0.997
LRP5	O75197-1.2	W478R	Pathogenic	0.998
LRP5	O75197-1.2	W478S	Pathogenic	0.999
LRP5	O75197-1.2	W478T	Pathogenic	0.998
LRP5	O75197-1.2	W478V	Pathogenic	1.0
LRP5	O75197-1.2	W478Y	Pathogenic	0.915
LRP5	O75197-1.2	G479A	Pathogenic	0.932
LRP5	O75197-1.2	G479C	Pathogenic	0.995
LRP5	O75197-1.2	G479D	Pathogenic	0.964
LRP5	O75197-1.2	G479E	Pathogenic	0.989
LRP5	O75197-1.2	G479F	Pathogenic	0.989
LRP5	O75197-1.2	G479H	Pathogenic	0.993
LRP5	O75197-1.2	G479I	Pathogenic	0.996
LRP5	O75197-1.2	G479K	Pathogenic	0.984
LRP5	O75197-1.2	G479L	Pathogenic	0.997
LRP5	O75197-1.2	G479M	Pathogenic	0.994
LRP5	O75197-1.2	G479N	Pathogenic	0.91
LRP5	O75197-1.2	G479P	Pathogenic	0.988
LRP5	O75197-1.2	G479Q	Pathogenic	0.992
LRP5	O75197-1.2	G479R	Pathogenic	0.984
LRP5	O75197-1.2	G479S	Pathogenic	0.946
LRP5	O75197-1.2	G479T	Pathogenic	0.992
LRP5	O75197-1.2	G479V	Pathogenic	0.994
LRP5	O75197-1.2	G479W	Pathogenic	0.951
LRP5	O75197-1.2	G479Y	Pathogenic	0.995
LRP5	O75197-1.2	E480A	Pathogenic	0.941
LRP5	O75197-1.2	E480C	Pathogenic	0.996
LRP5	O75197-1.2	E480D	Pathogenic	0.548
LRP5	O75197-1.2	E480F	Pathogenic	0.976
LRP5	O75197-1.2	E480G	Pathogenic	0.984
LRP5	O75197-1.2	E480H	Pathogenic	0.865
LRP5	O75197-1.2	E480I	Pathogenic	0.976
LRP5	O75197-1.2	E480K	Pathogenic	0.749
LRP5	O75197-1.2	E480L	Pathogenic	0.978
LRP5	O75197-1.2	E480M	Pathogenic	0.957
LRP5	O75197-1.2	E480N	Pathogenic	0.925
LRP5	O75197-1.2	E480P	Pathogenic	0.919
LRP5	O75197-1.2	E480Q	Neutral	0.489
LRP5	O75197-1.2	E480R	Pathogenic	0.898
LRP5	O75197-1.2	E480S	Pathogenic	0.878
LRP5	O75197-1.2	E480T	Pathogenic	0.945
LRP5	O75197-1.2	E480V	Pathogenic	0.958
LRP5	O75197-1.2	E480W	Pathogenic	0.962
LRP5	O75197-1.2	E480Y	Pathogenic	0.965
LRP5	O75197-1.2	N481A	Neutral	0.046
LRP5	O75197-1.2	N481C	Neutral	0.077
LRP5	O75197-1.2	N481D	Neutral	0.003
LRP5	O75197-1.2	N481E	Neutral	0.012
LRP5	O75197-1.2	N481F	Neutral	0.037
LRP5	O75197-1.2	N481G	Neutral	0.007
LRP5	O75197-1.2	N481H	Neutral	0.002
LRP5	O75197-1.2	N481I	Neutral	0.037
LRP5	O75197-1.2	N481K	Neutral	0.008
LRP5	O75197-1.2	N481L	Neutral	0.041
LRP5	O75197-1.2	N481M	Neutral	0.021
LRP5	O75197-1.2	N481P	Neutral	0.034
LRP5	O75197-1.2	N481Q	Neutral	0.009
LRP5	O75197-1.2	N481R	Neutral	0.008
LRP5	O75197-1.2	N481S	Neutral	0.002
LRP5	O75197-1.2	N481T	Neutral	0.006
LRP5	O75197-1.2	N481V	Neutral	0.063
LRP5	O75197-1.2	N481W	Neutral	0.069
LRP5	O75197-1.2	N481Y	Neutral	0.026
LRP5	O75197-1.2	P482A	Pathogenic	0.992
LRP5	O75197-1.2	P482C	Pathogenic	0.999
LRP5	O75197-1.2	P482D	Pathogenic	0.98
LRP5	O75197-1.2	P482E	Pathogenic	0.982
LRP5	O75197-1.2	P482F	Pathogenic	0.999
LRP5	O75197-1.2	P482G	Pathogenic	0.996
LRP5	O75197-1.2	P482H	Pathogenic	0.997
LRP5	O75197-1.2	P482I	Pathogenic	0.998
LRP5	O75197-1.2	P482K	Pathogenic	0.974
LRP5	O75197-1.2	P482L	Pathogenic	0.999
LRP5	O75197-1.2	P482M	Pathogenic	0.997
LRP5	O75197-1.2	P482N	Pathogenic	0.994
LRP5	O75197-1.2	P482Q	Pathogenic	0.987
LRP5	O75197-1.2	P482R	Pathogenic	0.991
LRP5	O75197-1.2	P482S	Pathogenic	0.989
LRP5	O75197-1.2	P482T	Pathogenic	0.992
LRP5	O75197-1.2	P482V	Pathogenic	0.997
LRP5	O75197-1.2	P482W	Pathogenic	0.999
LRP5	O75197-1.2	P482Y	Pathogenic	0.999
LRP5	O75197-1.2	K483A	Pathogenic	0.991
LRP5	O75197-1.2	K483C	Pathogenic	0.998
LRP5	O75197-1.2	K483D	Pathogenic	0.997
LRP5	O75197-1.2	K483E	Pathogenic	0.967
LRP5	O75197-1.2	K483F	Pathogenic	0.997
LRP5	O75197-1.2	K483G	Pathogenic	0.998
LRP5	O75197-1.2	K483H	Pathogenic	0.993
LRP5	O75197-1.2	K483I	Pathogenic	0.997
LRP5	O75197-1.2	K483L	Pathogenic	0.99
LRP5	O75197-1.2	K483M	Pathogenic	0.981
LRP5	O75197-1.2	K483N	Pathogenic	0.988
LRP5	O75197-1.2	K483P	Pathogenic	0.987
LRP5	O75197-1.2	K483Q	Pathogenic	0.953
LRP5	O75197-1.2	K483R	Pathogenic	0.929
LRP5	O75197-1.2	K483S	Pathogenic	0.98
LRP5	O75197-1.2	K483T	Pathogenic	0.992
LRP5	O75197-1.2	K483V	Pathogenic	0.994
LRP5	O75197-1.2	K483W	Pathogenic	0.995
LRP5	O75197-1.2	K483Y	Pathogenic	0.995
LRP5	O75197-1.2	I484A	Pathogenic	0.985
LRP5	O75197-1.2	I484C	Pathogenic	0.992
LRP5	O75197-1.2	I484D	Pathogenic	0.996
LRP5	O75197-1.2	I484E	Pathogenic	0.996
LRP5	O75197-1.2	I484F	Pathogenic	0.989
LRP5	O75197-1.2	I484G	Pathogenic	0.999
LRP5	O75197-1.2	I484H	Pathogenic	0.998
LRP5	O75197-1.2	I484K	Pathogenic	0.995
LRP5	O75197-1.2	I484L	Pathogenic	0.899
LRP5	O75197-1.2	I484M	Pathogenic	0.947
LRP5	O75197-1.2	I484N	Pathogenic	0.996
LRP5	O75197-1.2	I484P	Pathogenic	0.999
LRP5	O75197-1.2	I484Q	Pathogenic	0.998
LRP5	O75197-1.2	I484R	Pathogenic	0.995
LRP5	O75197-1.2	I484S	Pathogenic	0.993
LRP5	O75197-1.2	I484T	Pathogenic	0.985
LRP5	O75197-1.2	I484V	Pathogenic	0.648
LRP5	O75197-1.2	I484W	Pathogenic	0.999
LRP5	O75197-1.2	I484Y	Pathogenic	0.992
LRP5	O75197-1.2	E485A	Pathogenic	0.993
LRP5	O75197-1.2	E485C	Pathogenic	1.0
LRP5	O75197-1.2	E485D	Pathogenic	0.917
LRP5	O75197-1.2	E485F	Pathogenic	0.997
LRP5	O75197-1.2	E485G	Pathogenic	0.998
LRP5	O75197-1.2	E485H	Pathogenic	0.983
LRP5	O75197-1.2	E485I	Pathogenic	0.997
LRP5	O75197-1.2	E485K	Pathogenic	0.965
LRP5	O75197-1.2	E485L	Pathogenic	0.998
LRP5	O75197-1.2	E485M	Pathogenic	0.995
LRP5	O75197-1.2	E485N	Pathogenic	0.991
LRP5	O75197-1.2	E485P	Pathogenic	0.99
LRP5	O75197-1.2	E485Q	Pathogenic	0.897
LRP5	O75197-1.2	E485R	Pathogenic	0.988
LRP5	O75197-1.2	E485S	Pathogenic	0.985
LRP5	O75197-1.2	E485T	Pathogenic	0.994
LRP5	O75197-1.2	E485V	Pathogenic	0.995
LRP5	O75197-1.2	E485W	Pathogenic	0.996
LRP5	O75197-1.2	E485Y	Pathogenic	0.996
LRP5	O75197-1.2	C486A	Pathogenic	0.612
LRP5	O75197-1.2	C486D	Pathogenic	0.945
LRP5	O75197-1.2	C486E	Pathogenic	0.983
LRP5	O75197-1.2	C486F	Pathogenic	0.925
LRP5	O75197-1.2	C486G	Pathogenic	0.97
LRP5	O75197-1.2	C486H	Pathogenic	0.974
LRP5	O75197-1.2	C486I	Pathogenic	0.803
LRP5	O75197-1.2	C486K	Pathogenic	0.93
LRP5	O75197-1.2	C486L	Pathogenic	0.817
LRP5	O75197-1.2	C486M	Pathogenic	0.872
LRP5	O75197-1.2	C486N	Pathogenic	0.952
LRP5	O75197-1.2	C486P	Pathogenic	0.985
LRP5	O75197-1.2	C486Q	Pathogenic	0.965
LRP5	O75197-1.2	C486R	Pathogenic	0.928
LRP5	O75197-1.2	C486S	Pathogenic	0.781
LRP5	O75197-1.2	C486T	Pathogenic	0.824
LRP5	O75197-1.2	C486V	Pathogenic	0.877
LRP5	O75197-1.2	C486W	Pathogenic	0.887
LRP5	O75197-1.2	C486Y	Pathogenic	0.961
LRP5	O75197-1.2	A487C	Pathogenic	0.953
LRP5	O75197-1.2	A487D	Pathogenic	0.992
LRP5	O75197-1.2	A487E	Pathogenic	0.979
LRP5	O75197-1.2	A487F	Pathogenic	0.988
LRP5	O75197-1.2	A487G	Pathogenic	0.966
LRP5	O75197-1.2	A487H	Pathogenic	0.996
LRP5	O75197-1.2	A487I	Pathogenic	0.966
LRP5	O75197-1.2	A487K	Pathogenic	0.971
LRP5	O75197-1.2	A487L	Pathogenic	0.969
LRP5	O75197-1.2	A487M	Pathogenic	0.979
LRP5	O75197-1.2	A487N	Pathogenic	0.993
LRP5	O75197-1.2	A487P	Pathogenic	0.987
LRP5	O75197-1.2	A487Q	Pathogenic	0.985
LRP5	O75197-1.2	A487R	Pathogenic	0.97
LRP5	O75197-1.2	A487S	Pathogenic	0.902
LRP5	O75197-1.2	A487T	Pathogenic	0.972
LRP5	O75197-1.2	A487V	Pathogenic	0.941
LRP5	O75197-1.2	A487W	Pathogenic	0.994
LRP5	O75197-1.2	A487Y	Pathogenic	0.994
LRP5	O75197-1.2	N488A	Neutral	0.241
LRP5	O75197-1.2	N488C	Neutral	0.353
LRP5	O75197-1.2	N488D	Neutral	0.022
LRP5	O75197-1.2	N488E	Neutral	0.071
LRP5	O75197-1.2	N488F	Neutral	0.202
LRP5	O75197-1.2	N488G	Neutral	0.042
LRP5	O75197-1.2	N488H	Neutral	0.013
LRP5	O75197-1.2	N488I	Neutral	0.203
LRP5	O75197-1.2	N488K	Neutral	0.051
LRP5	O75197-1.2	N488L	Neutral	0.218
LRP5	O75197-1.2	N488M	Neutral	0.122
LRP5	O75197-1.2	N488P	Neutral	0.186
LRP5	O75197-1.2	N488Q	Neutral	0.053
LRP5	O75197-1.2	N488R	Neutral	0.049
LRP5	O75197-1.2	N488S	Neutral	0.015
LRP5	O75197-1.2	N488T	Neutral	0.036
LRP5	O75197-1.2	N488V	Neutral	0.307
LRP5	O75197-1.2	N488W	Neutral	0.328
LRP5	O75197-1.2	N488Y	Neutral	0.147
LRP5	O75197-1.2	L489A	Pathogenic	0.966
LRP5	O75197-1.2	L489C	Pathogenic	0.982
LRP5	O75197-1.2	L489D	Pathogenic	0.997
LRP5	O75197-1.2	L489E	Pathogenic	0.992
LRP5	O75197-1.2	L489F	Pathogenic	0.97
LRP5	O75197-1.2	L489G	Pathogenic	0.998
LRP5	O75197-1.2	L489H	Pathogenic	0.996
LRP5	O75197-1.2	L489I	Pathogenic	0.777
LRP5	O75197-1.2	L489K	Pathogenic	0.967
LRP5	O75197-1.2	L489M	Pathogenic	0.715
LRP5	O75197-1.2	L489N	Pathogenic	0.992
LRP5	O75197-1.2	L489P	Pathogenic	0.997
LRP5	O75197-1.2	L489Q	Pathogenic	0.983
LRP5	O75197-1.2	L489R	Pathogenic	0.966
LRP5	O75197-1.2	L489S	Pathogenic	0.985
LRP5	O75197-1.2	L489T	Pathogenic	0.966
LRP5	O75197-1.2	L489V	Pathogenic	0.88
LRP5	O75197-1.2	L489W	Pathogenic	0.995
LRP5	O75197-1.2	L489Y	Pathogenic	0.982
LRP5	O75197-1.2	D490A	Pathogenic	0.996
LRP5	O75197-1.2	D490C	Pathogenic	0.998
LRP5	O75197-1.2	D490E	Pathogenic	0.872
LRP5	O75197-1.2	D490F	Pathogenic	0.995
LRP5	O75197-1.2	D490G	Pathogenic	0.991
LRP5	O75197-1.2	D490H	Pathogenic	0.99
LRP5	O75197-1.2	D490I	Pathogenic	0.995
LRP5	O75197-1.2	D490K	Pathogenic	0.994
LRP5	O75197-1.2	D490L	Pathogenic	0.998
LRP5	O75197-1.2	D490M	Pathogenic	0.997
LRP5	O75197-1.2	D490N	Pathogenic	0.954
LRP5	O75197-1.2	D490P	Pathogenic	0.983
LRP5	O75197-1.2	D490Q	Pathogenic	0.977
LRP5	O75197-1.2	D490R	Pathogenic	0.998
LRP5	O75197-1.2	D490S	Pathogenic	0.974
LRP5	O75197-1.2	D490T	Pathogenic	0.989
LRP5	O75197-1.2	D490V	Pathogenic	0.997
LRP5	O75197-1.2	D490W	Pathogenic	0.997
LRP5	O75197-1.2	D490Y	Pathogenic	0.998
LRP5	O75197-1.2	G491A	Pathogenic	0.975
LRP5	O75197-1.2	G491C	Pathogenic	0.998
LRP5	O75197-1.2	G491D	Pathogenic	0.987
LRP5	O75197-1.2	G491E	Pathogenic	0.996
LRP5	O75197-1.2	G491F	Pathogenic	0.996
LRP5	O75197-1.2	G491H	Pathogenic	0.997
LRP5	O75197-1.2	G491I	Pathogenic	0.999
LRP5	O75197-1.2	G491K	Pathogenic	0.994
LRP5	O75197-1.2	G491L	Pathogenic	0.999
LRP5	O75197-1.2	G491M	Pathogenic	0.998
LRP5	O75197-1.2	G491N	Pathogenic	0.967
LRP5	O75197-1.2	G491P	Pathogenic	0.996
LRP5	O75197-1.2	G491Q	Pathogenic	0.997
LRP5	O75197-1.2	G491R	Pathogenic	0.994
LRP5	O75197-1.2	G491S	Pathogenic	0.98
LRP5	O75197-1.2	G491T	Pathogenic	0.997
LRP5	O75197-1.2	G491V	Pathogenic	0.998
LRP5	O75197-1.2	G491W	Pathogenic	0.982
LRP5	O75197-1.2	G491Y	Pathogenic	0.998
LRP5	O75197-1.2	Q492A	Neutral	0.051
LRP5	O75197-1.2	Q492C	Neutral	0.219
LRP5	O75197-1.2	Q492D	Neutral	0.018
LRP5	O75197-1.2	Q492E	Neutral	0.002
LRP5	O75197-1.2	Q492F	Neutral	0.121
LRP5	O75197-1.2	Q492G	Neutral	0.173
LRP5	O75197-1.2	Q492H	Neutral	0.022
LRP5	O75197-1.2	Q492I	Neutral	0.122
LRP5	O75197-1.2	Q492K	Neutral	0.005
LRP5	O75197-1.2	Q492L	Neutral	0.048
LRP5	O75197-1.2	Q492M	Neutral	0.008
LRP5	O75197-1.2	Q492N	Neutral	0.021
LRP5	O75197-1.2	Q492P	Neutral	0.037
LRP5	O75197-1.2	Q492R	Neutral	0.005
LRP5	O75197-1.2	Q492S	Neutral	0.024
LRP5	O75197-1.2	Q492T	Neutral	0.055
LRP5	O75197-1.2	Q492V	Neutral	0.072
LRP5	O75197-1.2	Q492W	Neutral	0.028
LRP5	O75197-1.2	Q492Y	Neutral	0.03
LRP5	O75197-1.2	E493A	Neutral	0.407
LRP5	O75197-1.2	E493C	Pathogenic	0.916
LRP5	O75197-1.2	E493D	Neutral	0.05
LRP5	O75197-1.2	E493F	Pathogenic	0.634
LRP5	O75197-1.2	E493G	Pathogenic	0.727
LRP5	O75197-1.2	E493H	Neutral	0.218
LRP5	O75197-1.2	E493I	Pathogenic	0.635
LRP5	O75197-1.2	E493K	Neutral	0.115
LRP5	O75197-1.2	E493L	Pathogenic	0.656
LRP5	O75197-1.2	E493M	Neutral	0.488
LRP5	O75197-1.2	E493N	Neutral	0.348
LRP5	O75197-1.2	E493P	Neutral	0.33
LRP5	O75197-1.2	E493Q	Neutral	0.04
LRP5	O75197-1.2	E493R	Neutral	0.276
LRP5	O75197-1.2	E493S	Neutral	0.237
LRP5	O75197-1.2	E493T	Neutral	0.428
LRP5	O75197-1.2	E493V	Neutral	0.496
LRP5	O75197-1.2	E493W	Pathogenic	0.523
LRP5	O75197-1.2	E493Y	Pathogenic	0.542
LRP5	O75197-1.2	R494A	Pathogenic	0.987
LRP5	O75197-1.2	R494C	Pathogenic	0.997
LRP5	O75197-1.2	R494D	Pathogenic	0.998
LRP5	O75197-1.2	R494E	Pathogenic	0.984
LRP5	O75197-1.2	R494F	Pathogenic	0.995
LRP5	O75197-1.2	R494G	Pathogenic	0.997
LRP5	O75197-1.2	R494H	Pathogenic	0.969
LRP5	O75197-1.2	R494I	Pathogenic	0.995
LRP5	O75197-1.2	R494K	Pathogenic	0.905
LRP5	O75197-1.2	R494L	Pathogenic	0.986
LRP5	O75197-1.2	R494M	Pathogenic	0.973
LRP5	O75197-1.2	R494N	Pathogenic	0.983
LRP5	O75197-1.2	R494P	Pathogenic	0.994
LRP5	O75197-1.2	R494Q	Pathogenic	0.934
LRP5	O75197-1.2	R494S	Pathogenic	0.99
LRP5	O75197-1.2	R494T	Pathogenic	0.988
LRP5	O75197-1.2	R494V	Pathogenic	0.997
LRP5	O75197-1.2	R494W	Pathogenic	0.993
LRP5	O75197-1.2	R494Y	Pathogenic	0.993
LRP5	O75197-1.2	R495A	Neutral	0.009
LRP5	O75197-1.2	R495C	Neutral	0.047
LRP5	O75197-1.2	R495D	Neutral	0.073
LRP5	O75197-1.2	R495E	Neutral	0.008
LRP5	O75197-1.2	R495F	Neutral	0.026
LRP5	O75197-1.2	R495G	Neutral	0.036
LRP5	O75197-1.2	R495H	Neutral	0.004
LRP5	O75197-1.2	R495I	Neutral	0.025
LRP5	O75197-1.2	R495K	Neutral	0.001
LRP5	O75197-1.2	R495L	Neutral	0.009
LRP5	O75197-1.2	R495M	Neutral	0.005
LRP5	O75197-1.2	R495N	Neutral	0.007
LRP5	O75197-1.2	R495P	Neutral	0.02
LRP5	O75197-1.2	R495Q	Neutral	0.002
LRP5	O75197-1.2	R495S	Neutral	0.013
LRP5	O75197-1.2	R495T	Neutral	0.01
LRP5	O75197-1.2	R495V	Neutral	0.04
LRP5	O75197-1.2	R495W	Neutral	0.017
LRP5	O75197-1.2	R495Y	Neutral	0.018
LRP5	O75197-1.2	V496A	Neutral	0.48
LRP5	O75197-1.2	V496C	Pathogenic	0.841
LRP5	O75197-1.2	V496D	Pathogenic	0.911
LRP5	O75197-1.2	V496E	Pathogenic	0.795
LRP5	O75197-1.2	V496F	Pathogenic	0.794
LRP5	O75197-1.2	V496G	Pathogenic	0.95
LRP5	O75197-1.2	V496H	Pathogenic	0.959
LRP5	O75197-1.2	V496I	Neutral	0.043
LRP5	O75197-1.2	V496K	Pathogenic	0.73
LRP5	O75197-1.2	V496L	Neutral	0.314
LRP5	O75197-1.2	V496M	Neutral	0.41
LRP5	O75197-1.2	V496N	Pathogenic	0.923
LRP5	O75197-1.2	V496P	Pathogenic	0.927
LRP5	O75197-1.2	V496Q	Pathogenic	0.848
LRP5	O75197-1.2	V496R	Pathogenic	0.889
LRP5	O75197-1.2	V496S	Pathogenic	0.864
LRP5	O75197-1.2	V496T	Neutral	0.479
LRP5	O75197-1.2	V496W	Pathogenic	0.957
LRP5	O75197-1.2	V496Y	Pathogenic	0.835
LRP5	O75197-1.2	L497A	Pathogenic	0.916
LRP5	O75197-1.2	L497C	Pathogenic	0.953
LRP5	O75197-1.2	L497D	Pathogenic	0.992
LRP5	O75197-1.2	L497E	Pathogenic	0.979
LRP5	O75197-1.2	L497F	Pathogenic	0.925
LRP5	O75197-1.2	L497G	Pathogenic	0.996
LRP5	O75197-1.2	L497H	Pathogenic	0.989
LRP5	O75197-1.2	L497I	Pathogenic	0.572
LRP5	O75197-1.2	L497K	Pathogenic	0.918
LRP5	O75197-1.2	L497M	Neutral	0.491
LRP5	O75197-1.2	L497N	Pathogenic	0.979
LRP5	O75197-1.2	L497P	Pathogenic	0.993
LRP5	O75197-1.2	L497Q	Pathogenic	0.957
LRP5	O75197-1.2	L497R	Pathogenic	0.915
LRP5	O75197-1.2	L497S	Pathogenic	0.961
LRP5	O75197-1.2	L497T	Pathogenic	0.915
LRP5	O75197-1.2	L497V	Pathogenic	0.737
LRP5	O75197-1.2	L497W	Pathogenic	0.986
LRP5	O75197-1.2	L497Y	Pathogenic	0.954
LRP5	O75197-1.2	V498A	Pathogenic	0.731
LRP5	O75197-1.2	V498C	Pathogenic	0.94
LRP5	O75197-1.2	V498D	Pathogenic	0.968
LRP5	O75197-1.2	V498E	Pathogenic	0.919
LRP5	O75197-1.2	V498F	Pathogenic	0.919
LRP5	O75197-1.2	V498G	Pathogenic	0.983
LRP5	O75197-1.2	V498H	Pathogenic	0.986
LRP5	O75197-1.2	V498I	Neutral	0.117
LRP5	O75197-1.2	V498K	Pathogenic	0.889
LRP5	O75197-1.2	V498L	Pathogenic	0.574
LRP5	O75197-1.2	V498M	Pathogenic	0.672
LRP5	O75197-1.2	V498N	Pathogenic	0.973
LRP5	O75197-1.2	V498P	Pathogenic	0.974
LRP5	O75197-1.2	V498Q	Pathogenic	0.943
LRP5	O75197-1.2	V498R	Pathogenic	0.959
LRP5	O75197-1.2	V498S	Pathogenic	0.949
LRP5	O75197-1.2	V498T	Pathogenic	0.73
LRP5	O75197-1.2	V498W	Pathogenic	0.985
LRP5	O75197-1.2	V498Y	Pathogenic	0.937
LRP5	O75197-1.2	N499A	Pathogenic	0.984
LRP5	O75197-1.2	N499C	Pathogenic	0.99
LRP5	O75197-1.2	N499D	Pathogenic	0.811
LRP5	O75197-1.2	N499E	Pathogenic	0.935
LRP5	O75197-1.2	N499F	Pathogenic	0.979
LRP5	O75197-1.2	N499G	Pathogenic	0.892
LRP5	O75197-1.2	N499H	Pathogenic	0.716
LRP5	O75197-1.2	N499I	Pathogenic	0.98
LRP5	O75197-1.2	N499K	Pathogenic	0.91
LRP5	O75197-1.2	N499L	Pathogenic	0.981
LRP5	O75197-1.2	N499M	Pathogenic	0.963
LRP5	O75197-1.2	N499P	Pathogenic	0.977
LRP5	O75197-1.2	N499Q	Pathogenic	0.913
LRP5	O75197-1.2	N499R	Pathogenic	0.907
LRP5	O75197-1.2	N499S	Pathogenic	0.745
LRP5	O75197-1.2	N499T	Pathogenic	0.876
LRP5	O75197-1.2	N499V	Pathogenic	0.988
LRP5	O75197-1.2	N499W	Pathogenic	0.989
LRP5	O75197-1.2	N499Y	Pathogenic	0.97
LRP5	O75197-1.2	A500C	Neutral	0.039
LRP5	O75197-1.2	A500D	Neutral	0.206
LRP5	O75197-1.2	A500E	Neutral	0.085
LRP5	O75197-1.2	A500F	Neutral	0.145
LRP5	O75197-1.2	A500G	Neutral	0.053
LRP5	O75197-1.2	A500H	Neutral	0.358
LRP5	O75197-1.2	A500I	Neutral	0.053
LRP5	O75197-1.2	A500K	Neutral	0.061
LRP5	O75197-1.2	A500L	Neutral	0.058
LRP5	O75197-1.2	A500M	Neutral	0.085
LRP5	O75197-1.2	A500N	Neutral	0.231
LRP5	O75197-1.2	A500P	Neutral	0.135
LRP5	O75197-1.2	A500Q	Neutral	0.119
LRP5	O75197-1.2	A500R	Neutral	0.059
LRP5	O75197-1.2	A500S	Neutral	0.018
LRP5	O75197-1.2	A500T	Neutral	0.066
LRP5	O75197-1.2	A500V	Neutral	0.031
LRP5	O75197-1.2	A500W	Neutral	0.245
LRP5	O75197-1.2	A500Y	Neutral	0.26
LRP5	O75197-1.2	S501A	Pathogenic	0.562
LRP5	O75197-1.2	S501C	Pathogenic	0.866
LRP5	O75197-1.2	S501D	Pathogenic	0.73
LRP5	O75197-1.2	S501E	Pathogenic	0.748
LRP5	O75197-1.2	S501F	Pathogenic	0.898
LRP5	O75197-1.2	S501G	Pathogenic	0.833
LRP5	O75197-1.2	S501H	Pathogenic	0.929
LRP5	O75197-1.2	S501I	Pathogenic	0.898
LRP5	O75197-1.2	S501K	Pathogenic	0.675
LRP5	O75197-1.2	S501L	Pathogenic	0.906
LRP5	O75197-1.2	S501M	Pathogenic	0.829
LRP5	O75197-1.2	S501N	Pathogenic	0.507
LRP5	O75197-1.2	S501P	Pathogenic	0.89
LRP5	O75197-1.2	S501Q	Pathogenic	0.81
LRP5	O75197-1.2	S501R	Pathogenic	0.859
LRP5	O75197-1.2	S501T	Pathogenic	0.568
LRP5	O75197-1.2	S501V	Pathogenic	0.939
LRP5	O75197-1.2	S501W	Pathogenic	0.944
LRP5	O75197-1.2	S501Y	Pathogenic	0.948
LRP5	O75197-1.2	L502A	Pathogenic	0.913
LRP5	O75197-1.2	L502C	Pathogenic	0.952
LRP5	O75197-1.2	L502D	Pathogenic	0.992
LRP5	O75197-1.2	L502E	Pathogenic	0.978
LRP5	O75197-1.2	L502F	Pathogenic	0.923
LRP5	O75197-1.2	L502G	Pathogenic	0.995
LRP5	O75197-1.2	L502H	Pathogenic	0.989
LRP5	O75197-1.2	L502I	Pathogenic	0.565
LRP5	O75197-1.2	L502K	Pathogenic	0.915
LRP5	O75197-1.2	L502M	Neutral	0.484
LRP5	O75197-1.2	L502N	Pathogenic	0.978
LRP5	O75197-1.2	L502P	Pathogenic	0.993
LRP5	O75197-1.2	L502Q	Pathogenic	0.956
LRP5	O75197-1.2	L502R	Pathogenic	0.913
LRP5	O75197-1.2	L502S	Pathogenic	0.96
LRP5	O75197-1.2	L502T	Pathogenic	0.913
LRP5	O75197-1.2	L502V	Pathogenic	0.732
LRP5	O75197-1.2	L502W	Pathogenic	0.986
LRP5	O75197-1.2	L502Y	Pathogenic	0.953
LRP5	O75197-1.2	G503A	Pathogenic	0.894
LRP5	O75197-1.2	G503C	Pathogenic	0.992
LRP5	O75197-1.2	G503D	Pathogenic	0.942
LRP5	O75197-1.2	G503E	Pathogenic	0.982
LRP5	O75197-1.2	G503F	Pathogenic	0.983
LRP5	O75197-1.2	G503H	Pathogenic	0.988
LRP5	O75197-1.2	G503I	Pathogenic	0.994
LRP5	O75197-1.2	G503K	Pathogenic	0.974
LRP5	O75197-1.2	G503L	Pathogenic	0.995
LRP5	O75197-1.2	G503M	Pathogenic	0.99
LRP5	O75197-1.2	G503N	Pathogenic	0.86
LRP5	O75197-1.2	G503P	Pathogenic	0.981
LRP5	O75197-1.2	G503Q	Pathogenic	0.987
LRP5	O75197-1.2	G503R	Pathogenic	0.973
LRP5	O75197-1.2	G503S	Pathogenic	0.914
LRP5	O75197-1.2	G503T	Pathogenic	0.987
LRP5	O75197-1.2	G503V	Pathogenic	0.99
LRP5	O75197-1.2	G503W	Pathogenic	0.921
LRP5	O75197-1.2	G503Y	Pathogenic	0.992
LRP5	O75197-1.2	W504A	Pathogenic	0.999
LRP5	O75197-1.2	W504C	Pathogenic	0.999
LRP5	O75197-1.2	W504D	Pathogenic	0.999
LRP5	O75197-1.2	W504E	Pathogenic	0.998
LRP5	O75197-1.2	W504F	Pathogenic	0.986
LRP5	O75197-1.2	W504G	Pathogenic	0.997
LRP5	O75197-1.2	W504H	Pathogenic	0.998
LRP5	O75197-1.2	W504I	Pathogenic	1.0
LRP5	O75197-1.2	W504K	Pathogenic	0.998
LRP5	O75197-1.2	W504L	Pathogenic	0.999
LRP5	O75197-1.2	W504M	Pathogenic	0.997
LRP5	O75197-1.2	W504N	Pathogenic	0.999
LRP5	O75197-1.2	W504P	Pathogenic	1.0
LRP5	O75197-1.2	W504Q	Pathogenic	0.997
LRP5	O75197-1.2	W504R	Pathogenic	0.998
LRP5	O75197-1.2	W504S	Pathogenic	0.999
LRP5	O75197-1.2	W504T	Pathogenic	0.998
LRP5	O75197-1.2	W504V	Pathogenic	1.0
LRP5	O75197-1.2	W504Y	Pathogenic	0.915
LRP5	O75197-1.2	P505A	Pathogenic	0.995
LRP5	O75197-1.2	P505C	Pathogenic	1.0
LRP5	O75197-1.2	P505D	Pathogenic	0.987
LRP5	O75197-1.2	P505E	Pathogenic	0.988
LRP5	O75197-1.2	P505F	Pathogenic	1.0
LRP5	O75197-1.2	P505G	Pathogenic	0.998
LRP5	O75197-1.2	P505H	Pathogenic	0.998
LRP5	O75197-1.2	P505I	Pathogenic	0.999
LRP5	O75197-1.2	P505K	Pathogenic	0.983
LRP5	O75197-1.2	P505L	Pathogenic	0.999
LRP5	O75197-1.2	P505M	Pathogenic	0.998
LRP5	O75197-1.2	P505N	Pathogenic	0.996
LRP5	O75197-1.2	P505Q	Pathogenic	0.992
LRP5	O75197-1.2	P505R	Pathogenic	0.994
LRP5	O75197-1.2	P505S	Pathogenic	0.993
LRP5	O75197-1.2	P505T	Pathogenic	0.995
LRP5	O75197-1.2	P505V	Pathogenic	0.998
LRP5	O75197-1.2	P505W	Pathogenic	0.999
LRP5	O75197-1.2	P505Y	Pathogenic	0.999
LRP5	O75197-1.2	N506A	Pathogenic	0.999
LRP5	O75197-1.2	N506C	Pathogenic	0.999
LRP5	O75197-1.2	N506D	Pathogenic	0.982
LRP5	O75197-1.2	N506E	Pathogenic	0.995
LRP5	O75197-1.2	N506F	Pathogenic	0.998
LRP5	O75197-1.2	N506G	Pathogenic	0.991
LRP5	O75197-1.2	N506H	Pathogenic	0.97
LRP5	O75197-1.2	N506I	Pathogenic	0.998
LRP5	O75197-1.2	N506K	Pathogenic	0.992
LRP5	O75197-1.2	N506L	Pathogenic	0.999
LRP5	O75197-1.2	N506M	Pathogenic	0.997
LRP5	O75197-1.2	N506P	Pathogenic	0.998
LRP5	O75197-1.2	N506Q	Pathogenic	0.993
LRP5	O75197-1.2	N506R	Pathogenic	0.992
LRP5	O75197-1.2	N506S	Pathogenic	0.974
LRP5	O75197-1.2	N506T	Pathogenic	0.989
LRP5	O75197-1.2	N506V	Pathogenic	0.999
LRP5	O75197-1.2	N506W	Pathogenic	0.999
LRP5	O75197-1.2	N506Y	Pathogenic	0.998
LRP5	O75197-1.2	G507A	Pathogenic	0.983
LRP5	O75197-1.2	G507C	Pathogenic	0.999
LRP5	O75197-1.2	G507D	Pathogenic	0.991
LRP5	O75197-1.2	G507E	Pathogenic	0.997
LRP5	O75197-1.2	G507F	Pathogenic	0.997
LRP5	O75197-1.2	G507H	Pathogenic	0.998
LRP5	O75197-1.2	G507I	Pathogenic	0.999
LRP5	O75197-1.2	G507K	Pathogenic	0.996
LRP5	O75197-1.2	G507L	Pathogenic	0.999
LRP5	O75197-1.2	G507M	Pathogenic	0.998
LRP5	O75197-1.2	G507N	Pathogenic	0.977
LRP5	O75197-1.2	G507P	Pathogenic	0.997
LRP5	O75197-1.2	G507Q	Pathogenic	0.998
LRP5	O75197-1.2	G507R	Pathogenic	0.996
LRP5	O75197-1.2	G507S	Pathogenic	0.986
LRP5	O75197-1.2	G507T	Pathogenic	0.998
LRP5	O75197-1.2	G507V	Pathogenic	0.999
LRP5	O75197-1.2	G507W	Pathogenic	0.988
LRP5	O75197-1.2	G507Y	Pathogenic	0.999
LRP5	O75197-1.2	L508A	Pathogenic	0.93
LRP5	O75197-1.2	L508C	Pathogenic	0.962
LRP5	O75197-1.2	L508D	Pathogenic	0.993
LRP5	O75197-1.2	L508E	Pathogenic	0.983
LRP5	O75197-1.2	L508F	Pathogenic	0.938
LRP5	O75197-1.2	L508G	Pathogenic	0.996
LRP5	O75197-1.2	L508H	Pathogenic	0.991
LRP5	O75197-1.2	L508I	Pathogenic	0.622
LRP5	O75197-1.2	L508K	Pathogenic	0.932
LRP5	O75197-1.2	L508M	Pathogenic	0.542
LRP5	O75197-1.2	L508N	Pathogenic	0.983
LRP5	O75197-1.2	L508P	Pathogenic	0.995
LRP5	O75197-1.2	L508Q	Pathogenic	0.965
LRP5	O75197-1.2	L508R	Pathogenic	0.93
LRP5	O75197-1.2	L508S	Pathogenic	0.968
LRP5	O75197-1.2	L508T	Pathogenic	0.93
LRP5	O75197-1.2	L508V	Pathogenic	0.775
LRP5	O75197-1.2	L508W	Pathogenic	0.989
LRP5	O75197-1.2	L508Y	Pathogenic	0.962
LRP5	O75197-1.2	A509C	Pathogenic	0.965
LRP5	O75197-1.2	A509D	Pathogenic	0.994
LRP5	O75197-1.2	A509E	Pathogenic	0.984
LRP5	O75197-1.2	A509F	Pathogenic	0.991
LRP5	O75197-1.2	A509G	Pathogenic	0.974
LRP5	O75197-1.2	A509H	Pathogenic	0.997
LRP5	O75197-1.2	A509I	Pathogenic	0.974
LRP5	O75197-1.2	A509K	Pathogenic	0.978
LRP5	O75197-1.2	A509L	Pathogenic	0.976
LRP5	O75197-1.2	A509M	Pathogenic	0.984
LRP5	O75197-1.2	A509N	Pathogenic	0.995
LRP5	O75197-1.2	A509P	Pathogenic	0.991
LRP5	O75197-1.2	A509Q	Pathogenic	0.989
LRP5	O75197-1.2	A509R	Pathogenic	0.977
LRP5	O75197-1.2	A509S	Pathogenic	0.925
LRP5	O75197-1.2	A509T	Pathogenic	0.979
LRP5	O75197-1.2	A509V	Pathogenic	0.956
LRP5	O75197-1.2	A509W	Pathogenic	0.995
LRP5	O75197-1.2	A509Y	Pathogenic	0.996
LRP5	O75197-1.2	L510A	Pathogenic	0.909
LRP5	O75197-1.2	L510C	Pathogenic	0.949
LRP5	O75197-1.2	L510D	Pathogenic	0.991
LRP5	O75197-1.2	L510E	Pathogenic	0.977
LRP5	O75197-1.2	L510F	Pathogenic	0.919
LRP5	O75197-1.2	L510G	Pathogenic	0.995
LRP5	O75197-1.2	L510H	Pathogenic	0.988
LRP5	O75197-1.2	L510I	Pathogenic	0.551
LRP5	O75197-1.2	L510K	Pathogenic	0.911
LRP5	O75197-1.2	L510M	Neutral	0.47
LRP5	O75197-1.2	L510N	Pathogenic	0.977
LRP5	O75197-1.2	L510P	Pathogenic	0.993
LRP5	O75197-1.2	L510Q	Pathogenic	0.953
LRP5	O75197-1.2	L510R	Pathogenic	0.908
LRP5	O75197-1.2	L510S	Pathogenic	0.957
LRP5	O75197-1.2	L510T	Pathogenic	0.908
LRP5	O75197-1.2	L510V	Pathogenic	0.721
LRP5	O75197-1.2	L510W	Pathogenic	0.985
LRP5	O75197-1.2	L510Y	Pathogenic	0.95
LRP5	O75197-1.2	D511A	Pathogenic	0.995
LRP5	O75197-1.2	D511C	Pathogenic	0.997
LRP5	O75197-1.2	D511E	Pathogenic	0.858
LRP5	O75197-1.2	D511F	Pathogenic	0.994
LRP5	O75197-1.2	D511G	Pathogenic	0.989
LRP5	O75197-1.2	D511H	Pathogenic	0.988
LRP5	O75197-1.2	D511I	Pathogenic	0.994
LRP5	O75197-1.2	D511K	Pathogenic	0.993
LRP5	O75197-1.2	D511L	Pathogenic	0.998
LRP5	O75197-1.2	D511M	Pathogenic	0.997
LRP5	O75197-1.2	D511N	Pathogenic	0.948
LRP5	O75197-1.2	D511P	Pathogenic	0.981
LRP5	O75197-1.2	D511Q	Pathogenic	0.975
LRP5	O75197-1.2	D511R	Pathogenic	0.998
LRP5	O75197-1.2	D511S	Pathogenic	0.97
LRP5	O75197-1.2	D511T	Pathogenic	0.987
LRP5	O75197-1.2	D511V	Pathogenic	0.997
LRP5	O75197-1.2	D511W	Pathogenic	0.997
LRP5	O75197-1.2	D511Y	Pathogenic	0.997
LRP5	O75197-1.2	L512A	Neutral	0.383
LRP5	O75197-1.2	L512C	Pathogenic	0.539
LRP5	O75197-1.2	L512D	Pathogenic	0.874
LRP5	O75197-1.2	L512E	Pathogenic	0.725
LRP5	O75197-1.2	L512F	Neutral	0.413
LRP5	O75197-1.2	L512G	Pathogenic	0.928
LRP5	O75197-1.2	L512H	Pathogenic	0.842
LRP5	O75197-1.2	L512I	Neutral	0.071
LRP5	O75197-1.2	L512K	Neutral	0.389
LRP5	O75197-1.2	L512M	Neutral	0.052
LRP5	O75197-1.2	L512N	Pathogenic	0.727
LRP5	O75197-1.2	L512P	Pathogenic	0.896
LRP5	O75197-1.2	L512Q	Pathogenic	0.559
LRP5	O75197-1.2	L512R	Neutral	0.381
LRP5	O75197-1.2	L512S	Pathogenic	0.583
LRP5	O75197-1.2	L512T	Neutral	0.382
LRP5	O75197-1.2	L512V	Neutral	0.138
LRP5	O75197-1.2	L512W	Pathogenic	0.805
LRP5	O75197-1.2	L512Y	Pathogenic	0.542
LRP5	O75197-1.2	Q513A	Neutral	0.054
LRP5	O75197-1.2	Q513C	Neutral	0.23
LRP5	O75197-1.2	Q513D	Neutral	0.019
LRP5	O75197-1.2	Q513E	Neutral	0.002
LRP5	O75197-1.2	Q513F	Neutral	0.128
LRP5	O75197-1.2	Q513G	Neutral	0.182
LRP5	O75197-1.2	Q513H	Neutral	0.023
LRP5	O75197-1.2	Q513I	Neutral	0.129
LRP5	O75197-1.2	Q513K	Neutral	0.005
LRP5	O75197-1.2	Q513L	Neutral	0.051
LRP5	O75197-1.2	Q513M	Neutral	0.009
LRP5	O75197-1.2	Q513N	Neutral	0.022
LRP5	O75197-1.2	Q513P	Neutral	0.04
LRP5	O75197-1.2	Q513R	Neutral	0.005
LRP5	O75197-1.2	Q513S	Neutral	0.025
LRP5	O75197-1.2	Q513T	Neutral	0.059
LRP5	O75197-1.2	Q513V	Neutral	0.076
LRP5	O75197-1.2	Q513W	Neutral	0.03
LRP5	O75197-1.2	Q513Y	Neutral	0.032
LRP5	O75197-1.2	E514A	Neutral	0.365
LRP5	O75197-1.2	E514C	Pathogenic	0.901
LRP5	O75197-1.2	E514D	Neutral	0.042
LRP5	O75197-1.2	E514F	Pathogenic	0.592
LRP5	O75197-1.2	E514G	Pathogenic	0.691
LRP5	O75197-1.2	E514H	Neutral	0.189
LRP5	O75197-1.2	E514I	Pathogenic	0.593
LRP5	O75197-1.2	E514K	Neutral	0.098
LRP5	O75197-1.2	E514L	Pathogenic	0.615
LRP5	O75197-1.2	E514M	Neutral	0.444
LRP5	O75197-1.2	E514N	Neutral	0.309
LRP5	O75197-1.2	E514P	Neutral	0.293
LRP5	O75197-1.2	E514Q	Neutral	0.034
LRP5	O75197-1.2	E514R	Neutral	0.242
LRP5	O75197-1.2	E514S	Neutral	0.206
LRP5	O75197-1.2	E514T	Neutral	0.386
LRP5	O75197-1.2	E514V	Neutral	0.452
LRP5	O75197-1.2	E514W	Neutral	0.479
LRP5	O75197-1.2	E514Y	Neutral	0.498
LRP5	O75197-1.2	G515A	Neutral	0.063
LRP5	O75197-1.2	G515C	Pathogenic	0.5
LRP5	O75197-1.2	G515D	Neutral	0.115
LRP5	O75197-1.2	G515E	Neutral	0.301
LRP5	O75197-1.2	G515F	Neutral	0.31
LRP5	O75197-1.2	G515H	Neutral	0.401
LRP5	O75197-1.2	G515I	Pathogenic	0.579
LRP5	O75197-1.2	G515K	Neutral	0.232
LRP5	O75197-1.2	G515L	Pathogenic	0.601
LRP5	O75197-1.2	G515M	Neutral	0.43
LRP5	O75197-1.2	G515N	Neutral	0.047
LRP5	O75197-1.2	G515P	Neutral	0.293
LRP5	O75197-1.2	G515Q	Neutral	0.383
LRP5	O75197-1.2	G515R	Neutral	0.226
LRP5	O75197-1.2	G515S	Neutral	0.078
LRP5	O75197-1.2	G515T	Neutral	0.384
LRP5	O75197-1.2	G515V	Neutral	0.44
LRP5	O75197-1.2	G515W	Neutral	0.086
LRP5	O75197-1.2	G515Y	Neutral	0.483
LRP5	O75197-1.2	K516A	Pathogenic	0.977
LRP5	O75197-1.2	K516C	Pathogenic	0.996
LRP5	O75197-1.2	K516D	Pathogenic	0.991
LRP5	O75197-1.2	K516E	Pathogenic	0.92
LRP5	O75197-1.2	K516F	Pathogenic	0.991
LRP5	O75197-1.2	K516G	Pathogenic	0.994
LRP5	O75197-1.2	K516H	Pathogenic	0.982
LRP5	O75197-1.2	K516I	Pathogenic	0.991
LRP5	O75197-1.2	K516L	Pathogenic	0.976
LRP5	O75197-1.2	K516M	Pathogenic	0.953
LRP5	O75197-1.2	K516N	Pathogenic	0.971
LRP5	O75197-1.2	K516P	Pathogenic	0.968
LRP5	O75197-1.2	K516Q	Pathogenic	0.888
LRP5	O75197-1.2	K516R	Pathogenic	0.838
LRP5	O75197-1.2	K516S	Pathogenic	0.95
LRP5	O75197-1.2	K516T	Pathogenic	0.979
LRP5	O75197-1.2	K516V	Pathogenic	0.984
LRP5	O75197-1.2	K516W	Pathogenic	0.987
LRP5	O75197-1.2	K516Y	Pathogenic	0.988
LRP5	O75197-1.2	L517A	Neutral	0.497
LRP5	O75197-1.2	L517C	Pathogenic	0.65
LRP5	O75197-1.2	L517D	Pathogenic	0.917
LRP5	O75197-1.2	L517E	Pathogenic	0.808
LRP5	O75197-1.2	L517F	Pathogenic	0.529
LRP5	O75197-1.2	L517G	Pathogenic	0.953
LRP5	O75197-1.2	L517H	Pathogenic	0.894
LRP5	O75197-1.2	L517I	Neutral	0.109
LRP5	O75197-1.2	L517K	Pathogenic	0.503
LRP5	O75197-1.2	L517M	Neutral	0.081
LRP5	O75197-1.2	L517N	Pathogenic	0.809
LRP5	O75197-1.2	L517P	Pathogenic	0.932
LRP5	O75197-1.2	L517Q	Pathogenic	0.669
LRP5	O75197-1.2	L517R	Neutral	0.495
LRP5	O75197-1.2	L517S	Pathogenic	0.69
LRP5	O75197-1.2	L517T	Neutral	0.496
LRP5	O75197-1.2	L517V	Neutral	0.204
LRP5	O75197-1.2	L517W	Pathogenic	0.868
LRP5	O75197-1.2	L517Y	Pathogenic	0.654
LRP5	O75197-1.2	Y518A	Pathogenic	0.999
LRP5	O75197-1.2	Y518C	Pathogenic	1.0
LRP5	O75197-1.2	Y518D	Pathogenic	0.999
LRP5	O75197-1.2	Y518E	Pathogenic	0.998
LRP5	O75197-1.2	Y518F	Pathogenic	0.806
LRP5	O75197-1.2	Y518G	Pathogenic	1.0
LRP5	O75197-1.2	Y518H	Pathogenic	0.925
LRP5	O75197-1.2	Y518I	Pathogenic	0.997
LRP5	O75197-1.2	Y518K	Pathogenic	0.997
LRP5	O75197-1.2	Y518L	Pathogenic	0.997
LRP5	O75197-1.2	Y518M	Pathogenic	0.998
LRP5	O75197-1.2	Y518N	Pathogenic	0.998
LRP5	O75197-1.2	Y518P	Pathogenic	1.0
LRP5	O75197-1.2	Y518Q	Pathogenic	0.996
LRP5	O75197-1.2	Y518R	Pathogenic	0.997
LRP5	O75197-1.2	Y518S	Pathogenic	0.999
LRP5	O75197-1.2	Y518T	Pathogenic	0.999
LRP5	O75197-1.2	Y518V	Pathogenic	0.998
LRP5	O75197-1.2	Y518W	Pathogenic	0.89
LRP5	O75197-1.2	W519A	Pathogenic	0.999
LRP5	O75197-1.2	W519C	Pathogenic	0.999
LRP5	O75197-1.2	W519D	Pathogenic	0.999
LRP5	O75197-1.2	W519E	Pathogenic	0.998
LRP5	O75197-1.2	W519F	Pathogenic	0.986
LRP5	O75197-1.2	W519G	Pathogenic	0.997
LRP5	O75197-1.2	W519H	Pathogenic	0.998
LRP5	O75197-1.2	W519I	Pathogenic	1.0
LRP5	O75197-1.2	W519K	Pathogenic	0.998
LRP5	O75197-1.2	W519L	Pathogenic	0.999
LRP5	O75197-1.2	W519M	Pathogenic	0.997
LRP5	O75197-1.2	W519N	Pathogenic	0.999
LRP5	O75197-1.2	W519P	Pathogenic	1.0
LRP5	O75197-1.2	W519Q	Pathogenic	0.997
LRP5	O75197-1.2	W519R	Pathogenic	0.998
LRP5	O75197-1.2	W519S	Pathogenic	0.999
LRP5	O75197-1.2	W519T	Pathogenic	0.998
LRP5	O75197-1.2	W519V	Pathogenic	1.0
LRP5	O75197-1.2	W519Y	Pathogenic	0.915
LRP5	O75197-1.2	G520A	Pathogenic	0.901
LRP5	O75197-1.2	G520C	Pathogenic	0.993
LRP5	O75197-1.2	G520D	Pathogenic	0.946
LRP5	O75197-1.2	G520E	Pathogenic	0.983
LRP5	O75197-1.2	G520F	Pathogenic	0.984
LRP5	O75197-1.2	G520H	Pathogenic	0.989
LRP5	O75197-1.2	G520I	Pathogenic	0.995
LRP5	O75197-1.2	G520K	Pathogenic	0.976
LRP5	O75197-1.2	G520L	Pathogenic	0.995
LRP5	O75197-1.2	G520M	Pathogenic	0.99
LRP5	O75197-1.2	G520N	Pathogenic	0.87
LRP5	O75197-1.2	G520P	Pathogenic	0.983
LRP5	O75197-1.2	G520Q	Pathogenic	0.988
LRP5	O75197-1.2	G520R	Pathogenic	0.975
LRP5	O75197-1.2	G520S	Pathogenic	0.92
LRP5	O75197-1.2	G520T	Pathogenic	0.988
LRP5	O75197-1.2	G520V	Pathogenic	0.991
LRP5	O75197-1.2	G520W	Pathogenic	0.927
LRP5	O75197-1.2	G520Y	Pathogenic	0.992
LRP5	O75197-1.2	D521A	Pathogenic	0.995
LRP5	O75197-1.2	D521C	Pathogenic	0.997
LRP5	O75197-1.2	D521E	Pathogenic	0.858
LRP5	O75197-1.2	D521F	Pathogenic	0.994
LRP5	O75197-1.2	D521G	Pathogenic	0.989
LRP5	O75197-1.2	D521H	Pathogenic	0.988
LRP5	O75197-1.2	D521I	Pathogenic	0.994
LRP5	O75197-1.2	D521K	Pathogenic	0.993
LRP5	O75197-1.2	D521L	Pathogenic	0.998
LRP5	O75197-1.2	D521M	Pathogenic	0.997
LRP5	O75197-1.2	D521N	Pathogenic	0.948
LRP5	O75197-1.2	D521P	Pathogenic	0.981
LRP5	O75197-1.2	D521Q	Pathogenic	0.975
LRP5	O75197-1.2	D521R	Pathogenic	0.998
LRP5	O75197-1.2	D521S	Pathogenic	0.97
LRP5	O75197-1.2	D521T	Pathogenic	0.987
LRP5	O75197-1.2	D521V	Pathogenic	0.997
LRP5	O75197-1.2	D521W	Pathogenic	0.997
LRP5	O75197-1.2	D521Y	Pathogenic	0.997
LRP5	O75197-1.2	A522C	Pathogenic	0.98
LRP5	O75197-1.2	A522D	Pathogenic	0.997
LRP5	O75197-1.2	A522E	Pathogenic	0.991
LRP5	O75197-1.2	A522F	Pathogenic	0.995
LRP5	O75197-1.2	A522G	Pathogenic	0.986
LRP5	O75197-1.2	A522H	Pathogenic	0.999
LRP5	O75197-1.2	A522I	Pathogenic	0.986
LRP5	O75197-1.2	A522K	Pathogenic	0.988
LRP5	O75197-1.2	A522L	Pathogenic	0.987
LRP5	O75197-1.2	A522M	Pathogenic	0.991
LRP5	O75197-1.2	A522N	Pathogenic	0.997
LRP5	O75197-1.2	A522P	Pathogenic	0.995
LRP5	O75197-1.2	A522Q	Pathogenic	0.994
LRP5	O75197-1.2	A522R	Pathogenic	0.987
LRP5	O75197-1.2	A522S	Pathogenic	0.957
LRP5	O75197-1.2	A522T	Pathogenic	0.988
LRP5	O75197-1.2	A522V	Pathogenic	0.975
LRP5	O75197-1.2	A522W	Pathogenic	0.997
LRP5	O75197-1.2	A522Y	Pathogenic	0.998
LRP5	O75197-1.2	K523A	Pathogenic	0.991
LRP5	O75197-1.2	K523C	Pathogenic	0.998
LRP5	O75197-1.2	K523D	Pathogenic	0.996
LRP5	O75197-1.2	K523E	Pathogenic	0.966
LRP5	O75197-1.2	K523F	Pathogenic	0.997
LRP5	O75197-1.2	K523G	Pathogenic	0.998
LRP5	O75197-1.2	K523H	Pathogenic	0.993
LRP5	O75197-1.2	K523I	Pathogenic	0.996
LRP5	O75197-1.2	K523L	Pathogenic	0.99
LRP5	O75197-1.2	K523M	Pathogenic	0.98
LRP5	O75197-1.2	K523N	Pathogenic	0.988
LRP5	O75197-1.2	K523P	Pathogenic	0.987
LRP5	O75197-1.2	K523Q	Pathogenic	0.951
LRP5	O75197-1.2	K523R	Pathogenic	0.927
LRP5	O75197-1.2	K523S	Pathogenic	0.979
LRP5	O75197-1.2	K523T	Pathogenic	0.991
LRP5	O75197-1.2	K523V	Pathogenic	0.993
LRP5	O75197-1.2	K523W	Pathogenic	0.995
LRP5	O75197-1.2	K523Y	Pathogenic	0.995
LRP5	O75197-1.2	T524A	Pathogenic	0.972
LRP5	O75197-1.2	T524C	Pathogenic	0.984
LRP5	O75197-1.2	T524D	Pathogenic	0.979
LRP5	O75197-1.2	T524E	Pathogenic	0.981
LRP5	O75197-1.2	T524F	Pathogenic	0.988
LRP5	O75197-1.2	T524G	Pathogenic	0.996
LRP5	O75197-1.2	T524H	Pathogenic	0.997
LRP5	O75197-1.2	T524I	Pathogenic	0.965
LRP5	O75197-1.2	T524K	Pathogenic	0.973
LRP5	O75197-1.2	T524L	Pathogenic	0.968
LRP5	O75197-1.2	T524M	Pathogenic	0.979
LRP5	O75197-1.2	T524N	Pathogenic	0.947
LRP5	O75197-1.2	T524P	Pathogenic	0.987
LRP5	O75197-1.2	T524Q	Pathogenic	0.987
LRP5	O75197-1.2	T524R	Pathogenic	0.972
LRP5	O75197-1.2	T524S	Pathogenic	0.904
LRP5	O75197-1.2	T524V	Pathogenic	0.941
LRP5	O75197-1.2	T524W	Pathogenic	0.982
LRP5	O75197-1.2	T524Y	Pathogenic	0.994
LRP5	O75197-1.2	D525A	Pathogenic	0.997
LRP5	O75197-1.2	D525C	Pathogenic	0.998
LRP5	O75197-1.2	D525E	Pathogenic	0.896
LRP5	O75197-1.2	D525F	Pathogenic	0.996
LRP5	O75197-1.2	D525G	Pathogenic	0.992
LRP5	O75197-1.2	D525H	Pathogenic	0.992
LRP5	O75197-1.2	D525I	Pathogenic	0.996
LRP5	O75197-1.2	D525K	Pathogenic	0.995
LRP5	O75197-1.2	D525L	Pathogenic	0.999
LRP5	O75197-1.2	D525M	Pathogenic	0.998
LRP5	O75197-1.2	D525N	Pathogenic	0.963
LRP5	O75197-1.2	D525P	Pathogenic	0.987
LRP5	O75197-1.2	D525Q	Pathogenic	0.982
LRP5	O75197-1.2	D525R	Pathogenic	0.998
LRP5	O75197-1.2	D525S	Pathogenic	0.979
LRP5	O75197-1.2	D525T	Pathogenic	0.991
LRP5	O75197-1.2	D525V	Pathogenic	0.998
LRP5	O75197-1.2	D525W	Pathogenic	0.998
LRP5	O75197-1.2	D525Y	Pathogenic	0.998
LRP5	O75197-1.2	K526A	Pathogenic	0.986
LRP5	O75197-1.2	K526C	Pathogenic	0.997
LRP5	O75197-1.2	K526D	Pathogenic	0.995
LRP5	O75197-1.2	K526E	Pathogenic	0.949
LRP5	O75197-1.2	K526F	Pathogenic	0.995
LRP5	O75197-1.2	K526G	Pathogenic	0.996
LRP5	O75197-1.2	K526H	Pathogenic	0.989
LRP5	O75197-1.2	K526I	Pathogenic	0.995
LRP5	O75197-1.2	K526L	Pathogenic	0.985
LRP5	O75197-1.2	K526M	Pathogenic	0.971
LRP5	O75197-1.2	K526N	Pathogenic	0.982
LRP5	O75197-1.2	K526P	Pathogenic	0.98
LRP5	O75197-1.2	K526Q	Pathogenic	0.929
LRP5	O75197-1.2	K526R	Pathogenic	0.895
LRP5	O75197-1.2	K526S	Pathogenic	0.969
LRP5	O75197-1.2	K526T	Pathogenic	0.987
LRP5	O75197-1.2	K526V	Pathogenic	0.99
LRP5	O75197-1.2	K526W	Pathogenic	0.992
LRP5	O75197-1.2	K526Y	Pathogenic	0.992
LRP5	O75197-1.2	I527A	Pathogenic	0.985
LRP5	O75197-1.2	I527C	Pathogenic	0.992
LRP5	O75197-1.2	I527D	Pathogenic	0.996
LRP5	O75197-1.2	I527E	Pathogenic	0.996
LRP5	O75197-1.2	I527F	Pathogenic	0.989
LRP5	O75197-1.2	I527G	Pathogenic	0.999
LRP5	O75197-1.2	I527H	Pathogenic	0.998
LRP5	O75197-1.2	I527K	Pathogenic	0.995
LRP5	O75197-1.2	I527L	Pathogenic	0.899
LRP5	O75197-1.2	I527M	Pathogenic	0.947
LRP5	O75197-1.2	I527N	Pathogenic	0.996
LRP5	O75197-1.2	I527P	Pathogenic	0.999
LRP5	O75197-1.2	I527Q	Pathogenic	0.998
LRP5	O75197-1.2	I527R	Pathogenic	0.995
LRP5	O75197-1.2	I527S	Pathogenic	0.993
LRP5	O75197-1.2	I527T	Pathogenic	0.985
LRP5	O75197-1.2	I527V	Pathogenic	0.648
LRP5	O75197-1.2	I527W	Pathogenic	0.999
LRP5	O75197-1.2	I527Y	Pathogenic	0.992
LRP5	O75197-1.2	E528A	Pathogenic	0.995
LRP5	O75197-1.2	E528C	Pathogenic	1.0
LRP5	O75197-1.2	E528D	Pathogenic	0.94
LRP5	O75197-1.2	E528F	Pathogenic	0.998
LRP5	O75197-1.2	E528G	Pathogenic	0.999
LRP5	O75197-1.2	E528H	Pathogenic	0.988
LRP5	O75197-1.2	E528I	Pathogenic	0.998
LRP5	O75197-1.2	E528K	Pathogenic	0.975
LRP5	O75197-1.2	E528L	Pathogenic	0.998
LRP5	O75197-1.2	E528M	Pathogenic	0.997
LRP5	O75197-1.2	E528N	Pathogenic	0.994
LRP5	O75197-1.2	E528P	Pathogenic	0.993
LRP5	O75197-1.2	E528Q	Pathogenic	0.925
LRP5	O75197-1.2	E528R	Pathogenic	0.991
LRP5	O75197-1.2	E528S	Pathogenic	0.989
LRP5	O75197-1.2	E528T	Pathogenic	0.996
LRP5	O75197-1.2	E528V	Pathogenic	0.997
LRP5	O75197-1.2	E528W	Pathogenic	0.997
LRP5	O75197-1.2	E528Y	Pathogenic	0.997
LRP5	O75197-1.2	V529A	Pathogenic	0.935
LRP5	O75197-1.2	V529C	Pathogenic	0.988
LRP5	O75197-1.2	V529D	Pathogenic	0.994
LRP5	O75197-1.2	V529E	Pathogenic	0.984
LRP5	O75197-1.2	V529F	Pathogenic	0.983
LRP5	O75197-1.2	V529G	Pathogenic	0.997
LRP5	O75197-1.2	V529H	Pathogenic	0.997
LRP5	O75197-1.2	V529I	Neutral	0.411
LRP5	O75197-1.2	V529K	Pathogenic	0.977
LRP5	O75197-1.2	V529L	Pathogenic	0.876
LRP5	O75197-1.2	V529M	Pathogenic	0.915
LRP5	O75197-1.2	V529N	Pathogenic	0.995
LRP5	O75197-1.2	V529P	Pathogenic	0.995
LRP5	O75197-1.2	V529Q	Pathogenic	0.989
LRP5	O75197-1.2	V529R	Pathogenic	0.992
LRP5	O75197-1.2	V529S	Pathogenic	0.99
LRP5	O75197-1.2	V529T	Pathogenic	0.934
LRP5	O75197-1.2	V529W	Pathogenic	0.997
LRP5	O75197-1.2	V529Y	Pathogenic	0.987
LRP5	O75197-1.2	I530A	Neutral	0.16
LRP5	O75197-1.2	I530C	Neutral	0.264
LRP5	O75197-1.2	I530D	Neutral	0.411
LRP5	O75197-1.2	I530E	Neutral	0.447
LRP5	O75197-1.2	I530F	Neutral	0.202
LRP5	O75197-1.2	I530G	Pathogenic	0.798
LRP5	O75197-1.2	I530H	Pathogenic	0.62
LRP5	O75197-1.2	I530K	Neutral	0.373
LRP5	O75197-1.2	I530L	Neutral	0.025
LRP5	O75197-1.2	I530M	Neutral	0.049
LRP5	O75197-1.2	I530N	Neutral	0.45
LRP5	O75197-1.2	I530P	Pathogenic	0.725
LRP5	O75197-1.2	I530Q	Pathogenic	0.542
LRP5	O75197-1.2	I530R	Neutral	0.365
LRP5	O75197-1.2	I530S	Neutral	0.3
LRP5	O75197-1.2	I530T	Neutral	0.159
LRP5	O75197-1.2	I530V	Neutral	0.005
LRP5	O75197-1.2	I530W	Pathogenic	0.822
LRP5	O75197-1.2	I530Y	Neutral	0.267
LRP5	O75197-1.2	N531A	Pathogenic	0.958
LRP5	O75197-1.2	N531C	Pathogenic	0.975
LRP5	O75197-1.2	N531D	Pathogenic	0.618
LRP5	O75197-1.2	N531E	Pathogenic	0.845
LRP5	O75197-1.2	N531F	Pathogenic	0.947
LRP5	O75197-1.2	N531G	Pathogenic	0.757
LRP5	O75197-1.2	N531H	Neutral	0.487
LRP5	O75197-1.2	N531I	Pathogenic	0.948
LRP5	O75197-1.2	N531K	Pathogenic	0.793
LRP5	O75197-1.2	N531L	Pathogenic	0.952
LRP5	O75197-1.2	N531M	Pathogenic	0.908
LRP5	O75197-1.2	N531P	Pathogenic	0.942
LRP5	O75197-1.2	N531Q	Pathogenic	0.799
LRP5	O75197-1.2	N531R	Pathogenic	0.787
LRP5	O75197-1.2	N531S	Pathogenic	0.525
LRP5	O75197-1.2	N531T	Pathogenic	0.727
LRP5	O75197-1.2	N531V	Pathogenic	0.969
LRP5	O75197-1.2	N531W	Pathogenic	0.972
LRP5	O75197-1.2	N531Y	Pathogenic	0.925
LRP5	O75197-1.2	V532A	Neutral	0.021
LRP5	O75197-1.2	V532C	Neutral	0.11
LRP5	O75197-1.2	V532D	Neutral	0.194
LRP5	O75197-1.2	V532E	Neutral	0.083
LRP5	O75197-1.2	V532F	Neutral	0.083
LRP5	O75197-1.2	V532G	Neutral	0.31
LRP5	O75197-1.2	V532H	Neutral	0.351
LRP5	O75197-1.2	V532I	Neutral	0.001
LRP5	O75197-1.2	V532K	Neutral	0.06
LRP5	O75197-1.2	V532L	Neutral	0.011
LRP5	O75197-1.2	V532M	Neutral	0.016
LRP5	O75197-1.2	V532N	Neutral	0.221
LRP5	O75197-1.2	V532P	Neutral	0.231
LRP5	O75197-1.2	V532Q	Neutral	0.116
LRP5	O75197-1.2	V532R	Neutral	0.157
LRP5	O75197-1.2	V532S	Neutral	0.129
LRP5	O75197-1.2	V532T	Neutral	0.021
LRP5	O75197-1.2	V532W	Neutral	0.345
LRP5	O75197-1.2	V532Y	Neutral	0.106
LRP5	O75197-1.2	D533A	Pathogenic	0.993
LRP5	O75197-1.2	D533C	Pathogenic	0.996
LRP5	O75197-1.2	D533E	Pathogenic	0.791
LRP5	O75197-1.2	D533F	Pathogenic	0.991
LRP5	O75197-1.2	D533G	Pathogenic	0.983
LRP5	O75197-1.2	D533H	Pathogenic	0.981
LRP5	O75197-1.2	D533I	Pathogenic	0.991
LRP5	O75197-1.2	D533K	Pathogenic	0.99
LRP5	O75197-1.2	D533L	Pathogenic	0.997
LRP5	O75197-1.2	D533M	Pathogenic	0.995
LRP5	O75197-1.2	D533N	Pathogenic	0.919
LRP5	O75197-1.2	D533P	Pathogenic	0.97
LRP5	O75197-1.2	D533Q	Pathogenic	0.96
LRP5	O75197-1.2	D533R	Pathogenic	0.996
LRP5	O75197-1.2	D533S	Pathogenic	0.953
LRP5	O75197-1.2	D533T	Pathogenic	0.98
LRP5	O75197-1.2	D533V	Pathogenic	0.995
LRP5	O75197-1.2	D533W	Pathogenic	0.995
LRP5	O75197-1.2	D533Y	Pathogenic	0.996
LRP5	O75197-1.2	G534A	Pathogenic	0.986
LRP5	O75197-1.2	G534C	Pathogenic	0.999
LRP5	O75197-1.2	G534D	Pathogenic	0.993
LRP5	O75197-1.2	G534E	Pathogenic	0.998
LRP5	O75197-1.2	G534F	Pathogenic	0.998
LRP5	O75197-1.2	G534H	Pathogenic	0.999
LRP5	O75197-1.2	G534I	Pathogenic	0.999
LRP5	O75197-1.2	G534K	Pathogenic	0.997
LRP5	O75197-1.2	G534L	Pathogenic	0.999
LRP5	O75197-1.2	G534M	Pathogenic	0.999
LRP5	O75197-1.2	G534N	Pathogenic	0.981
LRP5	O75197-1.2	G534P	Pathogenic	0.998
LRP5	O75197-1.2	G534Q	Pathogenic	0.998
LRP5	O75197-1.2	G534R	Pathogenic	0.997
LRP5	O75197-1.2	G534S	Pathogenic	0.989
LRP5	O75197-1.2	G534T	Pathogenic	0.998
LRP5	O75197-1.2	G534V	Pathogenic	0.999
LRP5	O75197-1.2	G534W	Pathogenic	0.99
LRP5	O75197-1.2	G534Y	Pathogenic	0.999
LRP5	O75197-1.2	T535A	Pathogenic	0.824
LRP5	O75197-1.2	T535C	Pathogenic	0.889
LRP5	O75197-1.2	T535D	Pathogenic	0.861
LRP5	O75197-1.2	T535E	Pathogenic	0.872
LRP5	O75197-1.2	T535F	Pathogenic	0.918
LRP5	O75197-1.2	T535G	Pathogenic	0.972
LRP5	O75197-1.2	T535H	Pathogenic	0.976
LRP5	O75197-1.2	T535I	Pathogenic	0.787
LRP5	O75197-1.2	T535K	Pathogenic	0.826
LRP5	O75197-1.2	T535L	Pathogenic	0.802
LRP5	O75197-1.2	T535M	Pathogenic	0.86
LRP5	O75197-1.2	T535N	Pathogenic	0.702
LRP5	O75197-1.2	T535P	Pathogenic	0.911
LRP5	O75197-1.2	T535Q	Pathogenic	0.907
LRP5	O75197-1.2	T535R	Pathogenic	0.821
LRP5	O75197-1.2	T535S	Pathogenic	0.555
LRP5	O75197-1.2	T535V	Pathogenic	0.679
LRP5	O75197-1.2	T535W	Pathogenic	0.876
LRP5	O75197-1.2	T535Y	Pathogenic	0.959
LRP5	O75197-1.2	K536A	Neutral	0.043
LRP5	O75197-1.2	K536C	Neutral	0.191
LRP5	O75197-1.2	K536D	Neutral	0.11
LRP5	O75197-1.2	K536E	Neutral	0.012
LRP5	O75197-1.2	K536F	Neutral	0.11
LRP5	O75197-1.2	K536G	Neutral	0.149
LRP5	O75197-1.2	K536H	Neutral	0.054
LRP5	O75197-1.2	K536I	Neutral	0.107
LRP5	O75197-1.2	K536L	Neutral	0.042
LRP5	O75197-1.2	K536M	Neutral	0.021
LRP5	O75197-1.2	K536N	Neutral	0.034
LRP5	O75197-1.2	K536P	Neutral	0.031
LRP5	O75197-1.2	K536Q	Neutral	0.008
LRP5	O75197-1.2	K536R	Neutral	0.005
LRP5	O75197-1.2	K536S	Neutral	0.02
LRP5	O75197-1.2	K536T	Neutral	0.047
LRP5	O75197-1.2	K536V	Neutral	0.061
LRP5	O75197-1.2	K536W	Neutral	0.073
LRP5	O75197-1.2	K536Y	Neutral	0.078
LRP5	O75197-1.2	R537A	Pathogenic	0.987
LRP5	O75197-1.2	R537C	Pathogenic	0.997
LRP5	O75197-1.2	R537D	Pathogenic	0.998
LRP5	O75197-1.2	R537E	Pathogenic	0.984
LRP5	O75197-1.2	R537F	Pathogenic	0.995
LRP5	O75197-1.2	R537G	Pathogenic	0.996
LRP5	O75197-1.2	R537H	Pathogenic	0.968
LRP5	O75197-1.2	R537I	Pathogenic	0.995
LRP5	O75197-1.2	R537K	Pathogenic	0.902
LRP5	O75197-1.2	R537L	Pathogenic	0.986
LRP5	O75197-1.2	R537M	Pathogenic	0.972
LRP5	O75197-1.2	R537N	Pathogenic	0.983
LRP5	O75197-1.2	R537P	Pathogenic	0.994
LRP5	O75197-1.2	R537Q	Pathogenic	0.932
LRP5	O75197-1.2	R537S	Pathogenic	0.99
LRP5	O75197-1.2	R537T	Pathogenic	0.988
LRP5	O75197-1.2	R537V	Pathogenic	0.997
LRP5	O75197-1.2	R537W	Pathogenic	0.993
LRP5	O75197-1.2	R537Y	Pathogenic	0.993
LRP5	O75197-1.2	R538A	Neutral	0.456
LRP5	O75197-1.2	R538C	Pathogenic	0.814
LRP5	O75197-1.2	R538D	Pathogenic	0.874
LRP5	O75197-1.2	R538E	Neutral	0.407
LRP5	O75197-1.2	R538F	Pathogenic	0.697
LRP5	O75197-1.2	R538G	Pathogenic	0.765
LRP5	O75197-1.2	R538H	Neutral	0.259
LRP5	O75197-1.2	R538I	Pathogenic	0.69
LRP5	O75197-1.2	R538K	Neutral	0.096
LRP5	O75197-1.2	R538L	Neutral	0.445
LRP5	O75197-1.2	R538M	Neutral	0.286
LRP5	O75197-1.2	R538N	Neutral	0.394
LRP5	O75197-1.2	R538P	Pathogenic	0.647
LRP5	O75197-1.2	R538Q	Neutral	0.135
LRP5	O75197-1.2	R538S	Pathogenic	0.535
LRP5	O75197-1.2	R538T	Neutral	0.477
LRP5	O75197-1.2	R538V	Pathogenic	0.785
LRP5	O75197-1.2	R538W	Pathogenic	0.602
LRP5	O75197-1.2	R538Y	Pathogenic	0.615
LRP5	O75197-1.2	T539A	Neutral	0.185
LRP5	O75197-1.2	T539C	Neutral	0.28
LRP5	O75197-1.2	T539D	Neutral	0.231
LRP5	O75197-1.2	T539E	Neutral	0.248
LRP5	O75197-1.2	T539F	Neutral	0.352
LRP5	O75197-1.2	T539G	Pathogenic	0.629
LRP5	O75197-1.2	T539H	Pathogenic	0.663
LRP5	O75197-1.2	T539I	Neutral	0.152
LRP5	O75197-1.2	T539K	Neutral	0.188
LRP5	O75197-1.2	T539L	Neutral	0.164
LRP5	O75197-1.2	T539M	Neutral	0.23
LRP5	O75197-1.2	T539N	Neutral	0.103
LRP5	O75197-1.2	T539P	Neutral	0.331
LRP5	O75197-1.2	T539Q	Neutral	0.322
LRP5	O75197-1.2	T539R	Neutral	0.182
LRP5	O75197-1.2	T539S	Neutral	0.057
LRP5	O75197-1.2	T539V	Neutral	0.093
LRP5	O75197-1.2	T539W	Neutral	0.256
LRP5	O75197-1.2	T539Y	Pathogenic	0.53
LRP5	O75197-1.2	L540A	Pathogenic	0.836
LRP5	O75197-1.2	L540C	Pathogenic	0.906
LRP5	O75197-1.2	L540D	Pathogenic	0.983
LRP5	O75197-1.2	L540E	Pathogenic	0.956
LRP5	O75197-1.2	L540F	Pathogenic	0.853
LRP5	O75197-1.2	L540G	Pathogenic	0.991
LRP5	O75197-1.2	L540H	Pathogenic	0.978
LRP5	O75197-1.2	L540I	Neutral	0.386
LRP5	O75197-1.2	L540K	Pathogenic	0.84
LRP5	O75197-1.2	L540M	Neutral	0.312
LRP5	O75197-1.2	L540N	Pathogenic	0.956
LRP5	O75197-1.2	L540P	Pathogenic	0.986
LRP5	O75197-1.2	L540Q	Pathogenic	0.913
LRP5	O75197-1.2	L540R	Pathogenic	0.835
LRP5	O75197-1.2	L540S	Pathogenic	0.92
LRP5	O75197-1.2	L540T	Pathogenic	0.835
LRP5	O75197-1.2	L540V	Pathogenic	0.569
LRP5	O75197-1.2	L540W	Pathogenic	0.971
LRP5	O75197-1.2	L540Y	Pathogenic	0.907
LRP5	O75197-1.2	L541A	Neutral	0.238
LRP5	O75197-1.2	L541C	Neutral	0.371
LRP5	O75197-1.2	L541D	Pathogenic	0.777
LRP5	O75197-1.2	L541E	Pathogenic	0.571
LRP5	O75197-1.2	L541F	Neutral	0.262
LRP5	O75197-1.2	L541G	Pathogenic	0.866
LRP5	O75197-1.2	L541H	Pathogenic	0.729
LRP5	O75197-1.2	L541I	Neutral	0.037
LRP5	O75197-1.2	L541K	Neutral	0.243
LRP5	O75197-1.2	L541M	Neutral	0.027
LRP5	O75197-1.2	L541N	Pathogenic	0.574
LRP5	O75197-1.2	L541P	Pathogenic	0.813
LRP5	O75197-1.2	L541Q	Neutral	0.39
LRP5	O75197-1.2	L541R	Neutral	0.237
LRP5	O75197-1.2	L541S	Neutral	0.414
LRP5	O75197-1.2	L541T	Neutral	0.237
LRP5	O75197-1.2	L541V	Neutral	0.075
LRP5	O75197-1.2	L541W	Pathogenic	0.675
LRP5	O75197-1.2	L541Y	Neutral	0.374
LRP5	O75197-1.2	E542A	Pathogenic	0.79
LRP5	O75197-1.2	E542C	Pathogenic	0.983
LRP5	O75197-1.2	E542D	Neutral	0.223
LRP5	O75197-1.2	E542F	Pathogenic	0.905
LRP5	O75197-1.2	E542G	Pathogenic	0.936
LRP5	O75197-1.2	E542H	Pathogenic	0.604
LRP5	O75197-1.2	E542I	Pathogenic	0.905
LRP5	O75197-1.2	E542K	Neutral	0.414
LRP5	O75197-1.2	E542L	Pathogenic	0.913
LRP5	O75197-1.2	E542M	Pathogenic	0.839
LRP5	O75197-1.2	E542N	Pathogenic	0.745
LRP5	O75197-1.2	E542P	Pathogenic	0.73
LRP5	O75197-1.2	E542Q	Neutral	0.185
LRP5	O75197-1.2	E542R	Pathogenic	0.675
LRP5	O75197-1.2	E542S	Pathogenic	0.629
LRP5	O75197-1.2	E542T	Pathogenic	0.804
LRP5	O75197-1.2	E542V	Pathogenic	0.843
LRP5	O75197-1.2	E542W	Pathogenic	0.857
LRP5	O75197-1.2	E542Y	Pathogenic	0.866
LRP5	O75197-1.2	D543A	Pathogenic	0.981
LRP5	O75197-1.2	D543C	Pathogenic	0.989
LRP5	O75197-1.2	D543E	Pathogenic	0.586
LRP5	O75197-1.2	D543F	Pathogenic	0.976
LRP5	O75197-1.2	D543G	Pathogenic	0.956
LRP5	O75197-1.2	D543H	Pathogenic	0.952
LRP5	O75197-1.2	D543I	Pathogenic	0.976
LRP5	O75197-1.2	D543K	Pathogenic	0.972
LRP5	O75197-1.2	D543L	Pathogenic	0.993
LRP5	O75197-1.2	D543M	Pathogenic	0.985
LRP5	O75197-1.2	D543N	Pathogenic	0.81
LRP5	O75197-1.2	D543P	Pathogenic	0.924
LRP5	O75197-1.2	D543Q	Pathogenic	0.899
LRP5	O75197-1.2	D543R	Pathogenic	0.99
LRP5	O75197-1.2	D543S	Pathogenic	0.885
LRP5	O75197-1.2	D543T	Pathogenic	0.948
LRP5	O75197-1.2	D543V	Pathogenic	0.986
LRP5	O75197-1.2	D543W	Pathogenic	0.987
LRP5	O75197-1.2	D543Y	Pathogenic	0.988
LRP5	O75197-1.2	K544A	Pathogenic	0.9
LRP5	O75197-1.2	K544C	Pathogenic	0.979
LRP5	O75197-1.2	K544D	Pathogenic	0.961
LRP5	O75197-1.2	K544E	Pathogenic	0.709
LRP5	O75197-1.2	K544F	Pathogenic	0.961
LRP5	O75197-1.2	K544G	Pathogenic	0.972
LRP5	O75197-1.2	K544H	Pathogenic	0.92
LRP5	O75197-1.2	K544I	Pathogenic	0.96
LRP5	O75197-1.2	K544L	Pathogenic	0.897
LRP5	O75197-1.2	K544M	Pathogenic	0.813
LRP5	O75197-1.2	K544N	Pathogenic	0.875
LRP5	O75197-1.2	K544P	Pathogenic	0.867
LRP5	O75197-1.2	K544Q	Pathogenic	0.628
LRP5	O75197-1.2	K544R	Pathogenic	0.525
LRP5	O75197-1.2	K544S	Pathogenic	0.803
LRP5	O75197-1.2	K544T	Pathogenic	0.908
LRP5	O75197-1.2	K544V	Pathogenic	0.928
LRP5	O75197-1.2	K544W	Pathogenic	0.94
LRP5	O75197-1.2	K544Y	Pathogenic	0.944
LRP5	O75197-1.2	L545A	Pathogenic	0.79
LRP5	O75197-1.2	L545C	Pathogenic	0.877
LRP5	O75197-1.2	L545D	Pathogenic	0.977
LRP5	O75197-1.2	L545E	Pathogenic	0.941
LRP5	O75197-1.2	L545F	Pathogenic	0.811
LRP5	O75197-1.2	L545G	Pathogenic	0.987
LRP5	O75197-1.2	L545H	Pathogenic	0.97
LRP5	O75197-1.2	L545I	Neutral	0.318
LRP5	O75197-1.2	L545K	Pathogenic	0.795
LRP5	O75197-1.2	L545M	Neutral	0.251
LRP5	O75197-1.2	L545N	Pathogenic	0.942
LRP5	O75197-1.2	L545P	Pathogenic	0.981
LRP5	O75197-1.2	L545Q	Pathogenic	0.885
LRP5	O75197-1.2	L545R	Pathogenic	0.789
LRP5	O75197-1.2	L545S	Pathogenic	0.895
LRP5	O75197-1.2	L545T	Pathogenic	0.79
LRP5	O75197-1.2	L545V	Neutral	0.494
LRP5	O75197-1.2	L545W	Pathogenic	0.962
LRP5	O75197-1.2	L545Y	Pathogenic	0.878
LRP5	O75197-1.2	P546A	Pathogenic	0.992
LRP5	O75197-1.2	P546C	Pathogenic	0.999
LRP5	O75197-1.2	P546D	Pathogenic	0.981
LRP5	O75197-1.2	P546E	Pathogenic	0.982
LRP5	O75197-1.2	P546F	Pathogenic	0.999
LRP5	O75197-1.2	P546G	Pathogenic	0.997
LRP5	O75197-1.2	P546H	Pathogenic	0.997
LRP5	O75197-1.2	P546I	Pathogenic	0.998
LRP5	O75197-1.2	P546K	Pathogenic	0.975
LRP5	O75197-1.2	P546L	Pathogenic	0.999
LRP5	O75197-1.2	P546M	Pathogenic	0.997
LRP5	O75197-1.2	P546N	Pathogenic	0.994
LRP5	O75197-1.2	P546Q	Pathogenic	0.988
LRP5	O75197-1.2	P546R	Pathogenic	0.991
LRP5	O75197-1.2	P546S	Pathogenic	0.99
LRP5	O75197-1.2	P546T	Pathogenic	0.992
LRP5	O75197-1.2	P546V	Pathogenic	0.997
LRP5	O75197-1.2	P546W	Pathogenic	0.999
LRP5	O75197-1.2	P546Y	Pathogenic	0.999
LRP5	O75197-1.2	H547A	Pathogenic	1.0
LRP5	O75197-1.2	H547C	Pathogenic	1.0
LRP5	O75197-1.2	H547D	Pathogenic	0.998
LRP5	O75197-1.2	H547E	Pathogenic	0.995
LRP5	O75197-1.2	H547F	Pathogenic	0.996
LRP5	O75197-1.2	H547G	Pathogenic	1.0
LRP5	O75197-1.2	H547I	Pathogenic	1.0
LRP5	O75197-1.2	H547K	Pathogenic	0.998
LRP5	O75197-1.2	H547L	Pathogenic	1.0
LRP5	O75197-1.2	H547M	Pathogenic	0.999
LRP5	O75197-1.2	H547N	Pathogenic	0.984
LRP5	O75197-1.2	H547P	Pathogenic	1.0
LRP5	O75197-1.2	H547Q	Pathogenic	0.996
LRP5	O75197-1.2	H547R	Pathogenic	0.993
LRP5	O75197-1.2	H547S	Pathogenic	0.999
LRP5	O75197-1.2	H547T	Pathogenic	1.0
LRP5	O75197-1.2	H547V	Pathogenic	1.0
LRP5	O75197-1.2	H547W	Pathogenic	0.998
LRP5	O75197-1.2	H547Y	Pathogenic	0.95
LRP5	O75197-1.2	I548A	Pathogenic	0.904
LRP5	O75197-1.2	I548C	Pathogenic	0.947
LRP5	O75197-1.2	I548D	Pathogenic	0.972
LRP5	O75197-1.2	I548E	Pathogenic	0.976
LRP5	O75197-1.2	I548F	Pathogenic	0.926
LRP5	O75197-1.2	I548G	Pathogenic	0.995
LRP5	O75197-1.2	I548H	Pathogenic	0.988
LRP5	O75197-1.2	I548K	Pathogenic	0.967
LRP5	O75197-1.2	I548L	Pathogenic	0.561
LRP5	O75197-1.2	I548M	Pathogenic	0.719
LRP5	O75197-1.2	I548N	Pathogenic	0.976
LRP5	O75197-1.2	I548P	Pathogenic	0.992
LRP5	O75197-1.2	I548Q	Pathogenic	0.983
LRP5	O75197-1.2	I548R	Pathogenic	0.966
LRP5	O75197-1.2	I548S	Pathogenic	0.955
LRP5	O75197-1.2	I548T	Pathogenic	0.904
LRP5	O75197-1.2	I548V	Neutral	0.209
LRP5	O75197-1.2	I548W	Pathogenic	0.996
LRP5	O75197-1.2	I548Y	Pathogenic	0.948
LRP5	O75197-1.2	F549A	Pathogenic	0.998
LRP5	O75197-1.2	F549C	Pathogenic	0.999
LRP5	O75197-1.2	F549D	Pathogenic	0.998
LRP5	O75197-1.2	F549E	Pathogenic	0.999
LRP5	O75197-1.2	F549G	Pathogenic	0.999
LRP5	O75197-1.2	F549H	Pathogenic	0.994
LRP5	O75197-1.2	F549I	Pathogenic	0.996
LRP5	O75197-1.2	F549K	Pathogenic	0.998
LRP5	O75197-1.2	F549L	Pathogenic	0.996
LRP5	O75197-1.2	F549M	Pathogenic	0.993
LRP5	O75197-1.2	F549N	Pathogenic	0.999
LRP5	O75197-1.2	F549P	Pathogenic	1.0
LRP5	O75197-1.2	F549Q	Pathogenic	0.999
LRP5	O75197-1.2	F549R	Pathogenic	0.998
LRP5	O75197-1.2	F549S	Pathogenic	0.998
LRP5	O75197-1.2	F549T	Pathogenic	0.998
LRP5	O75197-1.2	F549V	Pathogenic	0.998
LRP5	O75197-1.2	F549W	Pathogenic	0.981
LRP5	O75197-1.2	F549Y	Pathogenic	0.806
LRP5	O75197-1.2	G550A	Pathogenic	0.983
LRP5	O75197-1.2	G550C	Pathogenic	0.999
LRP5	O75197-1.2	G550D	Pathogenic	0.991
LRP5	O75197-1.2	G550E	Pathogenic	0.997
LRP5	O75197-1.2	G550F	Pathogenic	0.997
LRP5	O75197-1.2	G550H	Pathogenic	0.998
LRP5	O75197-1.2	G550I	Pathogenic	0.999
LRP5	O75197-1.2	G550K	Pathogenic	0.996
LRP5	O75197-1.2	G550L	Pathogenic	0.999
LRP5	O75197-1.2	G550M	Pathogenic	0.998
LRP5	O75197-1.2	G550N	Pathogenic	0.977
LRP5	O75197-1.2	G550P	Pathogenic	0.997
LRP5	O75197-1.2	G550Q	Pathogenic	0.998
LRP5	O75197-1.2	G550R	Pathogenic	0.996
LRP5	O75197-1.2	G550S	Pathogenic	0.986
LRP5	O75197-1.2	G550T	Pathogenic	0.998
LRP5	O75197-1.2	G550V	Pathogenic	0.999
LRP5	O75197-1.2	G550W	Pathogenic	0.988
LRP5	O75197-1.2	G550Y	Pathogenic	0.999
LRP5	O75197-1.2	F551A	Pathogenic	0.993
LRP5	O75197-1.2	F551C	Pathogenic	0.996
LRP5	O75197-1.2	F551D	Pathogenic	0.994
LRP5	O75197-1.2	F551E	Pathogenic	0.995
LRP5	O75197-1.2	F551G	Pathogenic	0.997
LRP5	O75197-1.2	F551H	Pathogenic	0.976
LRP5	O75197-1.2	F551I	Pathogenic	0.984
LRP5	O75197-1.2	F551K	Pathogenic	0.993
LRP5	O75197-1.2	F551L	Pathogenic	0.982
LRP5	O75197-1.2	F551M	Pathogenic	0.974
LRP5	O75197-1.2	F551N	Pathogenic	0.995
LRP5	O75197-1.2	F551P	Pathogenic	0.999
LRP5	O75197-1.2	F551Q	Pathogenic	0.996
LRP5	O75197-1.2	F551R	Pathogenic	0.993
LRP5	O75197-1.2	F551S	Pathogenic	0.99
LRP5	O75197-1.2	F551T	Pathogenic	0.993
LRP5	O75197-1.2	F551V	Pathogenic	0.991
LRP5	O75197-1.2	F551W	Pathogenic	0.928
LRP5	O75197-1.2	F551Y	Pathogenic	0.508
LRP5	O75197-1.2	T552A	Pathogenic	0.907
LRP5	O75197-1.2	T552C	Pathogenic	0.944
LRP5	O75197-1.2	T552D	Pathogenic	0.928
LRP5	O75197-1.2	T552E	Pathogenic	0.934
LRP5	O75197-1.2	T552F	Pathogenic	0.959
LRP5	O75197-1.2	T552G	Pathogenic	0.986
LRP5	O75197-1.2	T552H	Pathogenic	0.988
LRP5	O75197-1.2	T552I	Pathogenic	0.885
LRP5	O75197-1.2	T552K	Pathogenic	0.909
LRP5	O75197-1.2	T552L	Pathogenic	0.894
LRP5	O75197-1.2	T552M	Pathogenic	0.928
LRP5	O75197-1.2	T552N	Pathogenic	0.831
LRP5	O75197-1.2	T552P	Pathogenic	0.955
LRP5	O75197-1.2	T552Q	Pathogenic	0.953
LRP5	O75197-1.2	T552R	Pathogenic	0.906
LRP5	O75197-1.2	T552S	Pathogenic	0.723
LRP5	O75197-1.2	T552V	Pathogenic	0.816
LRP5	O75197-1.2	T552W	Pathogenic	0.937
LRP5	O75197-1.2	T552Y	Pathogenic	0.98
LRP5	O75197-1.2	L553A	Pathogenic	0.975
LRP5	O75197-1.2	L553C	Pathogenic	0.987
LRP5	O75197-1.2	L553D	Pathogenic	0.998
LRP5	O75197-1.2	L553E	Pathogenic	0.994
LRP5	O75197-1.2	L553F	Pathogenic	0.978
LRP5	O75197-1.2	L553G	Pathogenic	0.999
LRP5	O75197-1.2	L553H	Pathogenic	0.997
LRP5	O75197-1.2	L553I	Pathogenic	0.828
LRP5	O75197-1.2	L553K	Pathogenic	0.976
LRP5	O75197-1.2	L553M	Pathogenic	0.776
LRP5	O75197-1.2	L553N	Pathogenic	0.994
LRP5	O75197-1.2	L553P	Pathogenic	0.998
LRP5	O75197-1.2	L553Q	Pathogenic	0.988
LRP5	O75197-1.2	L553R	Pathogenic	0.975
LRP5	O75197-1.2	L553S	Pathogenic	0.989
LRP5	O75197-1.2	L553T	Pathogenic	0.975
LRP5	O75197-1.2	L553V	Pathogenic	0.91
LRP5	O75197-1.2	L553W	Pathogenic	0.996
LRP5	O75197-1.2	L553Y	Pathogenic	0.987
LRP5	O75197-1.2	L554A	Pathogenic	0.98
LRP5	O75197-1.2	L554C	Pathogenic	0.989
LRP5	O75197-1.2	L554D	Pathogenic	0.998
LRP5	O75197-1.2	L554E	Pathogenic	0.995
LRP5	O75197-1.2	L554F	Pathogenic	0.982
LRP5	O75197-1.2	L554G	Pathogenic	0.999
LRP5	O75197-1.2	L554H	Pathogenic	0.998
LRP5	O75197-1.2	L554I	Pathogenic	0.857
LRP5	O75197-1.2	L554K	Pathogenic	0.98
LRP5	O75197-1.2	L554M	Pathogenic	0.812
LRP5	O75197-1.2	L554N	Pathogenic	0.995
LRP5	O75197-1.2	L554P	Pathogenic	0.999
LRP5	O75197-1.2	L554Q	Pathogenic	0.99
LRP5	O75197-1.2	L554R	Pathogenic	0.98
LRP5	O75197-1.2	L554S	Pathogenic	0.991
LRP5	O75197-1.2	L554T	Pathogenic	0.98
LRP5	O75197-1.2	L554V	Pathogenic	0.926
LRP5	O75197-1.2	L554W	Pathogenic	0.997
LRP5	O75197-1.2	L554Y	Pathogenic	0.989
LRP5	O75197-1.2	G555A	Pathogenic	0.983
LRP5	O75197-1.2	G555C	Pathogenic	0.999
LRP5	O75197-1.2	G555D	Pathogenic	0.991
LRP5	O75197-1.2	G555E	Pathogenic	0.997
LRP5	O75197-1.2	G555F	Pathogenic	0.997
LRP5	O75197-1.2	G555H	Pathogenic	0.998
LRP5	O75197-1.2	G555I	Pathogenic	0.999
LRP5	O75197-1.2	G555K	Pathogenic	0.996
LRP5	O75197-1.2	G555L	Pathogenic	0.999
LRP5	O75197-1.2	G555M	Pathogenic	0.998
LRP5	O75197-1.2	G555N	Pathogenic	0.977
LRP5	O75197-1.2	G555P	Pathogenic	0.997
LRP5	O75197-1.2	G555Q	Pathogenic	0.998
LRP5	O75197-1.2	G555R	Pathogenic	0.996
LRP5	O75197-1.2	G555S	Pathogenic	0.986
LRP5	O75197-1.2	G555T	Pathogenic	0.998
LRP5	O75197-1.2	G555V	Pathogenic	0.999
LRP5	O75197-1.2	G555W	Pathogenic	0.988
LRP5	O75197-1.2	G555Y	Pathogenic	0.999
LRP5	O75197-1.2	D556A	Pathogenic	0.986
LRP5	O75197-1.2	D556C	Pathogenic	0.992
LRP5	O75197-1.2	D556E	Pathogenic	0.662
LRP5	O75197-1.2	D556F	Pathogenic	0.982
LRP5	O75197-1.2	D556G	Pathogenic	0.968
LRP5	O75197-1.2	D556H	Pathogenic	0.965
LRP5	O75197-1.2	D556I	Pathogenic	0.982
LRP5	O75197-1.2	D556K	Pathogenic	0.98
LRP5	O75197-1.2	D556L	Pathogenic	0.995
LRP5	O75197-1.2	D556M	Pathogenic	0.989
LRP5	O75197-1.2	D556N	Pathogenic	0.855
LRP5	O75197-1.2	D556P	Pathogenic	0.944
LRP5	O75197-1.2	D556Q	Pathogenic	0.925
LRP5	O75197-1.2	D556R	Pathogenic	0.993
LRP5	O75197-1.2	D556S	Pathogenic	0.914
LRP5	O75197-1.2	D556T	Pathogenic	0.962
LRP5	O75197-1.2	D556V	Pathogenic	0.99
LRP5	O75197-1.2	D556W	Pathogenic	0.991
LRP5	O75197-1.2	D556Y	Pathogenic	0.991
LRP5	O75197-1.2	F557A	Pathogenic	0.829
LRP5	O75197-1.2	F557C	Pathogenic	0.901
LRP5	O75197-1.2	F557D	Pathogenic	0.854
LRP5	O75197-1.2	F557E	Pathogenic	0.871
LRP5	O75197-1.2	F557G	Pathogenic	0.916
LRP5	O75197-1.2	F557H	Pathogenic	0.596
LRP5	O75197-1.2	F557I	Pathogenic	0.68
LRP5	O75197-1.2	F557K	Pathogenic	0.837
LRP5	O75197-1.2	F557L	Pathogenic	0.666
LRP5	O75197-1.2	F557M	Pathogenic	0.567
LRP5	O75197-1.2	F557N	Pathogenic	0.873
LRP5	O75197-1.2	F557P	Pathogenic	0.985
LRP5	O75197-1.2	F557Q	Pathogenic	0.908
LRP5	O75197-1.2	F557R	Pathogenic	0.833
LRP5	O75197-1.2	F557S	Pathogenic	0.782
LRP5	O75197-1.2	F557T	Pathogenic	0.828
LRP5	O75197-1.2	F557V	Pathogenic	0.792
LRP5	O75197-1.2	F557W	Neutral	0.313
LRP5	O75197-1.2	F557Y	Neutral	0.036
LRP5	O75197-1.2	I558A	Neutral	0.429
LRP5	O75197-1.2	I558C	Pathogenic	0.586
LRP5	O75197-1.2	I558D	Pathogenic	0.734
LRP5	O75197-1.2	I558E	Pathogenic	0.762
LRP5	O75197-1.2	I558F	Pathogenic	0.5
LRP5	O75197-1.2	I558G	Pathogenic	0.94
LRP5	O75197-1.2	I558H	Pathogenic	0.866
LRP5	O75197-1.2	I558K	Pathogenic	0.701
LRP5	O75197-1.2	I558L	Neutral	0.092
LRP5	O75197-1.2	I558M	Neutral	0.169
LRP5	O75197-1.2	I558N	Pathogenic	0.764
LRP5	O75197-1.2	I558P	Pathogenic	0.913
LRP5	O75197-1.2	I558Q	Pathogenic	0.824
LRP5	O75197-1.2	I558R	Pathogenic	0.694
LRP5	O75197-1.2	I558S	Pathogenic	0.629
LRP5	O75197-1.2	I558T	Neutral	0.428
LRP5	O75197-1.2	I558V	Neutral	0.021
LRP5	O75197-1.2	I558W	Pathogenic	0.948
LRP5	O75197-1.2	I558Y	Pathogenic	0.59
LRP5	O75197-1.2	Y559A	Pathogenic	0.999
LRP5	O75197-1.2	Y559C	Pathogenic	0.999
LRP5	O75197-1.2	Y559D	Pathogenic	0.999
LRP5	O75197-1.2	Y559E	Pathogenic	0.998
LRP5	O75197-1.2	Y559F	Pathogenic	0.778
LRP5	O75197-1.2	Y559G	Pathogenic	1.0
LRP5	O75197-1.2	Y559H	Pathogenic	0.912
LRP5	O75197-1.2	Y559I	Pathogenic	0.997
LRP5	O75197-1.2	Y559K	Pathogenic	0.997
LRP5	O75197-1.2	Y559L	Pathogenic	0.997
LRP5	O75197-1.2	Y559M	Pathogenic	0.998
LRP5	O75197-1.2	Y559N	Pathogenic	0.998
LRP5	O75197-1.2	Y559P	Pathogenic	1.0
LRP5	O75197-1.2	Y559Q	Pathogenic	0.995
LRP5	O75197-1.2	Y559R	Pathogenic	0.997
LRP5	O75197-1.2	Y559S	Pathogenic	0.999
LRP5	O75197-1.2	Y559T	Pathogenic	0.999
LRP5	O75197-1.2	Y559V	Pathogenic	0.998
LRP5	O75197-1.2	Y559W	Pathogenic	0.873
LRP5	O75197-1.2	W560A	Pathogenic	0.999
LRP5	O75197-1.2	W560C	Pathogenic	0.999
LRP5	O75197-1.2	W560D	Pathogenic	0.999
LRP5	O75197-1.2	W560E	Pathogenic	0.998
LRP5	O75197-1.2	W560F	Pathogenic	0.982
LRP5	O75197-1.2	W560G	Pathogenic	0.996
LRP5	O75197-1.2	W560H	Pathogenic	0.997
LRP5	O75197-1.2	W560I	Pathogenic	1.0
LRP5	O75197-1.2	W560K	Pathogenic	0.997
LRP5	O75197-1.2	W560L	Pathogenic	0.999
LRP5	O75197-1.2	W560M	Pathogenic	0.997
LRP5	O75197-1.2	W560N	Pathogenic	0.999
LRP5	O75197-1.2	W560P	Pathogenic	1.0
LRP5	O75197-1.2	W560Q	Pathogenic	0.996
LRP5	O75197-1.2	W560R	Pathogenic	0.997
LRP5	O75197-1.2	W560S	Pathogenic	0.999
LRP5	O75197-1.2	W560T	Pathogenic	0.997
LRP5	O75197-1.2	W560V	Pathogenic	1.0
LRP5	O75197-1.2	W560Y	Pathogenic	0.896
LRP5	O75197-1.2	T561A	Pathogenic	0.984
LRP5	O75197-1.2	T561C	Pathogenic	0.99
LRP5	O75197-1.2	T561D	Pathogenic	0.988
LRP5	O75197-1.2	T561E	Pathogenic	0.989
LRP5	O75197-1.2	T561F	Pathogenic	0.993
LRP5	O75197-1.2	T561G	Pathogenic	0.998
LRP5	O75197-1.2	T561H	Pathogenic	0.998
LRP5	O75197-1.2	T561I	Pathogenic	0.98
LRP5	O75197-1.2	T561K	Pathogenic	0.984
LRP5	O75197-1.2	T561L	Pathogenic	0.981
LRP5	O75197-1.2	T561M	Pathogenic	0.988
LRP5	O75197-1.2	T561N	Pathogenic	0.968
LRP5	O75197-1.2	T561P	Pathogenic	0.993
LRP5	O75197-1.2	T561Q	Pathogenic	0.992
LRP5	O75197-1.2	T561R	Pathogenic	0.983
LRP5	O75197-1.2	T561S	Pathogenic	0.942
LRP5	O75197-1.2	T561V	Pathogenic	0.965
LRP5	O75197-1.2	T561W	Pathogenic	0.989
LRP5	O75197-1.2	T561Y	Pathogenic	0.997
LRP5	O75197-1.2	D562A	Pathogenic	0.993
LRP5	O75197-1.2	D562C	Pathogenic	0.996
LRP5	O75197-1.2	D562E	Pathogenic	0.795
LRP5	O75197-1.2	D562F	Pathogenic	0.991
LRP5	O75197-1.2	D562G	Pathogenic	0.983
LRP5	O75197-1.2	D562H	Pathogenic	0.982
LRP5	O75197-1.2	D562I	Pathogenic	0.991
LRP5	O75197-1.2	D562K	Pathogenic	0.99
LRP5	O75197-1.2	D562L	Pathogenic	0.997
LRP5	O75197-1.2	D562M	Pathogenic	0.995
LRP5	O75197-1.2	D562N	Pathogenic	0.921
LRP5	O75197-1.2	D562P	Pathogenic	0.971
LRP5	O75197-1.2	D562Q	Pathogenic	0.961
LRP5	O75197-1.2	D562R	Pathogenic	0.997
LRP5	O75197-1.2	D562S	Pathogenic	0.955
LRP5	O75197-1.2	D562T	Pathogenic	0.981
LRP5	O75197-1.2	D562V	Pathogenic	0.995
LRP5	O75197-1.2	D562W	Pathogenic	0.995
LRP5	O75197-1.2	D562Y	Pathogenic	0.996
LRP5	O75197-1.2	W563A	Pathogenic	0.999
LRP5	O75197-1.2	W563C	Pathogenic	0.999
LRP5	O75197-1.2	W563D	Pathogenic	0.999
LRP5	O75197-1.2	W563E	Pathogenic	0.998
LRP5	O75197-1.2	W563F	Pathogenic	0.982
LRP5	O75197-1.2	W563G	Pathogenic	0.996
LRP5	O75197-1.2	W563H	Pathogenic	0.997
LRP5	O75197-1.2	W563I	Pathogenic	1.0
LRP5	O75197-1.2	W563K	Pathogenic	0.997
LRP5	O75197-1.2	W563L	Pathogenic	0.999
LRP5	O75197-1.2	W563M	Pathogenic	0.997
LRP5	O75197-1.2	W563N	Pathogenic	0.999
LRP5	O75197-1.2	W563P	Pathogenic	1.0
LRP5	O75197-1.2	W563Q	Pathogenic	0.996
LRP5	O75197-1.2	W563R	Pathogenic	0.997
LRP5	O75197-1.2	W563S	Pathogenic	0.999
LRP5	O75197-1.2	W563T	Pathogenic	0.997
LRP5	O75197-1.2	W563V	Pathogenic	1.0
LRP5	O75197-1.2	W563Y	Pathogenic	0.897
LRP5	O75197-1.2	Q564A	Pathogenic	0.996
LRP5	O75197-1.2	Q564C	Pathogenic	0.999
LRP5	O75197-1.2	Q564D	Pathogenic	0.988
LRP5	O75197-1.2	Q564E	Pathogenic	0.913
LRP5	O75197-1.2	Q564F	Pathogenic	0.998
LRP5	O75197-1.2	Q564G	Pathogenic	0.999
LRP5	O75197-1.2	Q564H	Pathogenic	0.99
LRP5	O75197-1.2	Q564I	Pathogenic	0.998
LRP5	O75197-1.2	Q564K	Pathogenic	0.958
LRP5	O75197-1.2	Q564L	Pathogenic	0.996
LRP5	O75197-1.2	Q564M	Pathogenic	0.974
LRP5	O75197-1.2	Q564N	Pathogenic	0.99
LRP5	O75197-1.2	Q564P	Pathogenic	0.994
LRP5	O75197-1.2	Q564R	Pathogenic	0.956
LRP5	O75197-1.2	Q564S	Pathogenic	0.991
LRP5	O75197-1.2	Q564T	Pathogenic	0.996
LRP5	O75197-1.2	Q564V	Pathogenic	0.997
LRP5	O75197-1.2	Q564W	Pathogenic	0.993
LRP5	O75197-1.2	Q564Y	Pathogenic	0.993
LRP5	O75197-1.2	R565A	Pathogenic	0.963
LRP5	O75197-1.2	R565C	Pathogenic	0.993
LRP5	O75197-1.2	R565D	Pathogenic	0.995
LRP5	O75197-1.2	R565E	Pathogenic	0.955
LRP5	O75197-1.2	R565F	Pathogenic	0.986
LRP5	O75197-1.2	R565G	Pathogenic	0.99
LRP5	O75197-1.2	R565H	Pathogenic	0.916
LRP5	O75197-1.2	R565I	Pathogenic	0.986
LRP5	O75197-1.2	R565K	Pathogenic	0.767
LRP5	O75197-1.2	R565L	Pathogenic	0.961
LRP5	O75197-1.2	R565M	Pathogenic	0.926
LRP5	O75197-1.2	R565N	Pathogenic	0.953
LRP5	O75197-1.2	R565P	Pathogenic	0.983
LRP5	O75197-1.2	R565Q	Pathogenic	0.829
LRP5	O75197-1.2	R565S	Pathogenic	0.973
LRP5	O75197-1.2	R565T	Pathogenic	0.966
LRP5	O75197-1.2	R565V	Pathogenic	0.991
LRP5	O75197-1.2	R565W	Pathogenic	0.979
LRP5	O75197-1.2	R565Y	Pathogenic	0.98
LRP5	O75197-1.2	R566A	Pathogenic	0.989
LRP5	O75197-1.2	R566C	Pathogenic	0.998
LRP5	O75197-1.2	R566D	Pathogenic	0.999
LRP5	O75197-1.2	R566E	Pathogenic	0.986
LRP5	O75197-1.2	R566F	Pathogenic	0.996
LRP5	O75197-1.2	R566G	Pathogenic	0.997
LRP5	O75197-1.2	R566H	Pathogenic	0.973
LRP5	O75197-1.2	R566I	Pathogenic	0.996
LRP5	O75197-1.2	R566K	Pathogenic	0.916
LRP5	O75197-1.2	R566L	Pathogenic	0.988
LRP5	O75197-1.2	R566M	Pathogenic	0.976
LRP5	O75197-1.2	R566N	Pathogenic	0.985
LRP5	O75197-1.2	R566P	Pathogenic	0.995
LRP5	O75197-1.2	R566Q	Pathogenic	0.941
LRP5	O75197-1.2	R566S	Pathogenic	0.992
LRP5	O75197-1.2	R566T	Pathogenic	0.989
LRP5	O75197-1.2	R566V	Pathogenic	0.997
LRP5	O75197-1.2	R566W	Pathogenic	0.994
LRP5	O75197-1.2	R566Y	Pathogenic	0.994
LRP5	O75197-1.2	S567A	Pathogenic	0.883
LRP5	O75197-1.2	S567C	Pathogenic	0.974
LRP5	O75197-1.2	S567D	Pathogenic	0.941
LRP5	O75197-1.2	S567E	Pathogenic	0.946
LRP5	O75197-1.2	S567F	Pathogenic	0.981
LRP5	O75197-1.2	S567G	Pathogenic	0.967
LRP5	O75197-1.2	S567H	Pathogenic	0.987
LRP5	O75197-1.2	S567I	Pathogenic	0.981
LRP5	O75197-1.2	S567K	Pathogenic	0.924
LRP5	O75197-1.2	S567L	Pathogenic	0.983
LRP5	O75197-1.2	S567M	Pathogenic	0.966
LRP5	O75197-1.2	S567N	Pathogenic	0.858
LRP5	O75197-1.2	S567P	Pathogenic	0.979
LRP5	O75197-1.2	S567Q	Pathogenic	0.962
LRP5	O75197-1.2	S567R	Pathogenic	0.973
LRP5	O75197-1.2	S567T	Pathogenic	0.885
LRP5	O75197-1.2	S567V	Pathogenic	0.989
LRP5	O75197-1.2	S567W	Pathogenic	0.99
LRP5	O75197-1.2	S567Y	Pathogenic	0.991
LRP5	O75197-1.2	I568A	Pathogenic	0.971
LRP5	O75197-1.2	I568C	Pathogenic	0.985
LRP5	O75197-1.2	I568D	Pathogenic	0.992
LRP5	O75197-1.2	I568E	Pathogenic	0.993
LRP5	O75197-1.2	I568F	Pathogenic	0.978
LRP5	O75197-1.2	I568G	Pathogenic	0.999
LRP5	O75197-1.2	I568H	Pathogenic	0.997
LRP5	O75197-1.2	I568K	Pathogenic	0.991
LRP5	O75197-1.2	I568L	Pathogenic	0.821
LRP5	O75197-1.2	I568M	Pathogenic	0.901
LRP5	O75197-1.2	I568N	Pathogenic	0.993
LRP5	O75197-1.2	I568P	Pathogenic	0.998
LRP5	O75197-1.2	I568Q	Pathogenic	0.995
LRP5	O75197-1.2	I568R	Pathogenic	0.99
LRP5	O75197-1.2	I568S	Pathogenic	0.987
LRP5	O75197-1.2	I568T	Pathogenic	0.971
LRP5	O75197-1.2	I568V	Neutral	0.486
LRP5	O75197-1.2	I568W	Pathogenic	0.999
LRP5	O75197-1.2	I568Y	Pathogenic	0.985
LRP5	O75197-1.2	E569A	Pathogenic	0.962
LRP5	O75197-1.2	E569C	Pathogenic	0.997
LRP5	O75197-1.2	E569D	Pathogenic	0.657
LRP5	O75197-1.2	E569F	Pathogenic	0.984
LRP5	O75197-1.2	E569G	Pathogenic	0.99
LRP5	O75197-1.2	E569H	Pathogenic	0.911
LRP5	O75197-1.2	E569I	Pathogenic	0.985
LRP5	O75197-1.2	E569K	Pathogenic	0.826
LRP5	O75197-1.2	E569L	Pathogenic	0.986
LRP5	O75197-1.2	E569M	Pathogenic	0.972
LRP5	O75197-1.2	E569N	Pathogenic	0.951
LRP5	O75197-1.2	E569P	Pathogenic	0.947
LRP5	O75197-1.2	E569Q	Pathogenic	0.603
LRP5	O75197-1.2	E569R	Pathogenic	0.933
LRP5	O75197-1.2	E569S	Pathogenic	0.919
LRP5	O75197-1.2	E569T	Pathogenic	0.965
LRP5	O75197-1.2	E569V	Pathogenic	0.973
LRP5	O75197-1.2	E569W	Pathogenic	0.976
LRP5	O75197-1.2	E569Y	Pathogenic	0.977
LRP5	O75197-1.2	R570A	Pathogenic	0.981
LRP5	O75197-1.2	R570C	Pathogenic	0.996
LRP5	O75197-1.2	R570D	Pathogenic	0.998
LRP5	O75197-1.2	R570E	Pathogenic	0.977
LRP5	O75197-1.2	R570F	Pathogenic	0.993
LRP5	O75197-1.2	R570G	Pathogenic	0.995
LRP5	O75197-1.2	R570H	Pathogenic	0.956
LRP5	O75197-1.2	R570I	Pathogenic	0.993
LRP5	O75197-1.2	R570K	Pathogenic	0.869
LRP5	O75197-1.2	R570L	Pathogenic	0.981
LRP5	O75197-1.2	R570M	Pathogenic	0.962
LRP5	O75197-1.2	R570N	Pathogenic	0.976
LRP5	O75197-1.2	R570P	Pathogenic	0.991
LRP5	O75197-1.2	R570Q	Pathogenic	0.908
LRP5	O75197-1.2	R570S	Pathogenic	0.986
LRP5	O75197-1.2	R570T	Pathogenic	0.983
LRP5	O75197-1.2	R570V	Pathogenic	0.996
LRP5	O75197-1.2	R570W	Pathogenic	0.99
LRP5	O75197-1.2	R570Y	Pathogenic	0.99
LRP5	O75197-1.2	V571A	Pathogenic	0.888
LRP5	O75197-1.2	V571C	Pathogenic	0.979
LRP5	O75197-1.2	V571D	Pathogenic	0.989
LRP5	O75197-1.2	V571E	Pathogenic	0.971
LRP5	O75197-1.2	V571F	Pathogenic	0.971
LRP5	O75197-1.2	V571G	Pathogenic	0.994
LRP5	O75197-1.2	V571H	Pathogenic	0.995
LRP5	O75197-1.2	V571I	Neutral	0.28
LRP5	O75197-1.2	V571K	Pathogenic	0.959
LRP5	O75197-1.2	V571L	Pathogenic	0.798
LRP5	O75197-1.2	V571M	Pathogenic	0.857
LRP5	O75197-1.2	V571N	Pathogenic	0.99
LRP5	O75197-1.2	V571P	Pathogenic	0.991
LRP5	O75197-1.2	V571Q	Pathogenic	0.98
LRP5	O75197-1.2	V571R	Pathogenic	0.986
LRP5	O75197-1.2	V571S	Pathogenic	0.982
LRP5	O75197-1.2	V571T	Pathogenic	0.888
LRP5	O75197-1.2	V571W	Pathogenic	0.995
LRP5	O75197-1.2	V571Y	Pathogenic	0.978
LRP5	O75197-1.2	H572A	Pathogenic	0.998
LRP5	O75197-1.2	H572C	Pathogenic	0.999
LRP5	O75197-1.2	H572D	Pathogenic	0.987
LRP5	O75197-1.2	H572E	Pathogenic	0.967
LRP5	O75197-1.2	H572F	Pathogenic	0.976
LRP5	O75197-1.2	H572G	Pathogenic	0.998
LRP5	O75197-1.2	H572I	Pathogenic	0.997
LRP5	O75197-1.2	H572K	Pathogenic	0.985
LRP5	O75197-1.2	H572L	Pathogenic	0.998
LRP5	O75197-1.2	H572M	Pathogenic	0.995
LRP5	O75197-1.2	H572N	Pathogenic	0.907
LRP5	O75197-1.2	H572P	Pathogenic	0.997
LRP5	O75197-1.2	H572Q	Pathogenic	0.977
LRP5	O75197-1.2	H572R	Pathogenic	0.953
LRP5	O75197-1.2	H572S	Pathogenic	0.993
LRP5	O75197-1.2	H572T	Pathogenic	0.998
LRP5	O75197-1.2	H572V	Pathogenic	0.998
LRP5	O75197-1.2	H572W	Pathogenic	0.987
LRP5	O75197-1.2	H572Y	Pathogenic	0.746
LRP5	O75197-1.2	K573A	Pathogenic	0.991
LRP5	O75197-1.2	K573C	Pathogenic	0.998
LRP5	O75197-1.2	K573D	Pathogenic	0.997
LRP5	O75197-1.2	K573E	Pathogenic	0.967
LRP5	O75197-1.2	K573F	Pathogenic	0.997
LRP5	O75197-1.2	K573G	Pathogenic	0.998
LRP5	O75197-1.2	K573H	Pathogenic	0.993
LRP5	O75197-1.2	K573I	Pathogenic	0.997
LRP5	O75197-1.2	K573L	Pathogenic	0.991
LRP5	O75197-1.2	K573M	Pathogenic	0.981
LRP5	O75197-1.2	K573N	Pathogenic	0.988
LRP5	O75197-1.2	K573P	Pathogenic	0.988
LRP5	O75197-1.2	K573Q	Pathogenic	0.954
LRP5	O75197-1.2	K573R	Pathogenic	0.931
LRP5	O75197-1.2	K573S	Pathogenic	0.98
LRP5	O75197-1.2	K573T	Pathogenic	0.992
LRP5	O75197-1.2	K573V	Pathogenic	0.994
LRP5	O75197-1.2	K573W	Pathogenic	0.995
LRP5	O75197-1.2	K573Y	Pathogenic	0.995
LRP5	O75197-1.2	V574A	Neutral	0.003
LRP5	O75197-1.2	V574C	Neutral	0.014
LRP5	O75197-1.2	V574D	Neutral	0.027
LRP5	O75197-1.2	V574E	Neutral	0.01
LRP5	O75197-1.2	V574F	Neutral	0.01
LRP5	O75197-1.2	V574G	Neutral	0.05
LRP5	O75197-1.2	V574H	Neutral	0.059
LRP5	O75197-1.2	V574I	Neutral	0.0
LRP5	O75197-1.2	V574K	Neutral	0.007
LRP5	O75197-1.2	V574L	Neutral	0.001
LRP5	O75197-1.2	V574M	Neutral	0.002
LRP5	O75197-1.2	V574N	Neutral	0.032
LRP5	O75197-1.2	V574P	Neutral	0.034
LRP5	O75197-1.2	V574Q	Neutral	0.015
LRP5	O75197-1.2	V574R	Neutral	0.021
LRP5	O75197-1.2	V574S	Neutral	0.017
LRP5	O75197-1.2	V574T	Neutral	0.003
LRP5	O75197-1.2	V574W	Neutral	0.058
LRP5	O75197-1.2	V574Y	Neutral	0.014
LRP5	O75197-1.2	K575A	Neutral	0.096
LRP5	O75197-1.2	K575C	Neutral	0.355
LRP5	O75197-1.2	K575D	Neutral	0.223
LRP5	O75197-1.2	K575E	Neutral	0.028
LRP5	O75197-1.2	K575F	Neutral	0.225
LRP5	O75197-1.2	K575G	Neutral	0.291
LRP5	O75197-1.2	K575H	Neutral	0.118
LRP5	O75197-1.2	K575I	Neutral	0.219
LRP5	O75197-1.2	K575L	Neutral	0.092
LRP5	O75197-1.2	K575M	Neutral	0.048
LRP5	O75197-1.2	K575N	Neutral	0.076
LRP5	O75197-1.2	K575P	Neutral	0.071
LRP5	O75197-1.2	K575Q	Neutral	0.019
LRP5	O75197-1.2	K575R	Neutral	0.013
LRP5	O75197-1.2	K575S	Neutral	0.046
LRP5	O75197-1.2	K575T	Neutral	0.103
LRP5	O75197-1.2	K575V	Neutral	0.132
LRP5	O75197-1.2	K575W	Neutral	0.155
LRP5	O75197-1.2	K575Y	Neutral	0.165
LRP5	O75197-1.2	A576C	Pathogenic	0.852
LRP5	O75197-1.2	A576D	Pathogenic	0.974
LRP5	O75197-1.2	A576E	Pathogenic	0.93
LRP5	O75197-1.2	A576F	Pathogenic	0.96
LRP5	O75197-1.2	A576G	Pathogenic	0.889
LRP5	O75197-1.2	A576H	Pathogenic	0.987
LRP5	O75197-1.2	A576I	Pathogenic	0.888
LRP5	O75197-1.2	A576K	Pathogenic	0.902
LRP5	O75197-1.2	A576L	Pathogenic	0.896
LRP5	O75197-1.2	A576M	Pathogenic	0.929
LRP5	O75197-1.2	A576N	Pathogenic	0.977
LRP5	O75197-1.2	A576P	Pathogenic	0.957
LRP5	O75197-1.2	A576Q	Pathogenic	0.95
LRP5	O75197-1.2	A576R	Pathogenic	0.899
LRP5	O75197-1.2	A576S	Pathogenic	0.722
LRP5	O75197-1.2	A576T	Pathogenic	0.908
LRP5	O75197-1.2	A576V	Pathogenic	0.819
LRP5	O75197-1.2	A576W	Pathogenic	0.979
LRP5	O75197-1.2	A576Y	Pathogenic	0.98
LRP5	O75197-1.2	S577A	Neutral	0.004
LRP5	O75197-1.2	S577C	Neutral	0.022
LRP5	O75197-1.2	S577D	Neutral	0.009
LRP5	O75197-1.2	S577E	Neutral	0.01
LRP5	O75197-1.2	S577F	Neutral	0.03
LRP5	O75197-1.2	S577G	Neutral	0.017
LRP5	O75197-1.2	S577H	Neutral	0.044
LRP5	O75197-1.2	S577I	Neutral	0.03
LRP5	O75197-1.2	S577K	Neutral	0.007
LRP5	O75197-1.2	S577L	Neutral	0.033
LRP5	O75197-1.2	S577M	Neutral	0.017
LRP5	O75197-1.2	S577N	Neutral	0.004
LRP5	O75197-1.2	S577P	Neutral	0.028
LRP5	O75197-1.2	S577Q	Neutral	0.015
LRP5	O75197-1.2	S577R	Neutral	0.021
LRP5	O75197-1.2	S577T	Neutral	0.005
LRP5	O75197-1.2	S577V	Neutral	0.051
LRP5	O75197-1.2	S577W	Neutral	0.056
LRP5	O75197-1.2	S577Y	Neutral	0.06
LRP5	O75197-1.2	R578A	Pathogenic	0.977
LRP5	O75197-1.2	R578C	Pathogenic	0.995
LRP5	O75197-1.2	R578D	Pathogenic	0.997
LRP5	O75197-1.2	R578E	Pathogenic	0.972
LRP5	O75197-1.2	R578F	Pathogenic	0.991
LRP5	O75197-1.2	R578G	Pathogenic	0.994
LRP5	O75197-1.2	R578H	Pathogenic	0.946
LRP5	O75197-1.2	R578I	Pathogenic	0.991
LRP5	O75197-1.2	R578K	Pathogenic	0.842
LRP5	O75197-1.2	R578L	Pathogenic	0.976
LRP5	O75197-1.2	R578M	Pathogenic	0.953
LRP5	O75197-1.2	R578N	Pathogenic	0.97
LRP5	O75197-1.2	R578P	Pathogenic	0.989
LRP5	O75197-1.2	R578Q	Pathogenic	0.887
LRP5	O75197-1.2	R578S	Pathogenic	0.983
LRP5	O75197-1.2	R578T	Pathogenic	0.979
LRP5	O75197-1.2	R578V	Pathogenic	0.995
LRP5	O75197-1.2	R578W	Pathogenic	0.987
LRP5	O75197-1.2	R578Y	Pathogenic	0.988
LRP5	O75197-1.2	D579A	Neutral	0.443
LRP5	O75197-1.2	D579C	Pathogenic	0.577
LRP5	O75197-1.2	D579E	Neutral	0.021
LRP5	O75197-1.2	D579F	Neutral	0.384
LRP5	O75197-1.2	D579G	Neutral	0.25
LRP5	O75197-1.2	D579H	Neutral	0.233
LRP5	O75197-1.2	D579I	Neutral	0.385
LRP5	O75197-1.2	D579K	Neutral	0.353
LRP5	O75197-1.2	D579L	Pathogenic	0.676
LRP5	O75197-1.2	D579M	Pathogenic	0.511
LRP5	O75197-1.2	D579N	Neutral	0.062
LRP5	O75197-1.2	D579P	Neutral	0.158
LRP5	O75197-1.2	D579Q	Neutral	0.121
LRP5	O75197-1.2	D579R	Pathogenic	0.616
LRP5	O75197-1.2	D579S	Neutral	0.106
LRP5	O75197-1.2	D579T	Neutral	0.221
LRP5	O75197-1.2	D579V	Pathogenic	0.522
LRP5	O75197-1.2	D579W	Pathogenic	0.545
LRP5	O75197-1.2	D579Y	Pathogenic	0.564
LRP5	O75197-1.2	V580A	Neutral	0.119
LRP5	O75197-1.2	V580C	Neutral	0.436
LRP5	O75197-1.2	V580D	Pathogenic	0.601
LRP5	O75197-1.2	V580E	Neutral	0.362
LRP5	O75197-1.2	V580F	Neutral	0.36
LRP5	O75197-1.2	V580G	Pathogenic	0.737
LRP5	O75197-1.2	V580H	Pathogenic	0.772
LRP5	O75197-1.2	V580I	Neutral	0.007
LRP5	O75197-1.2	V580K	Neutral	0.284
LRP5	O75197-1.2	V580L	Neutral	0.063
LRP5	O75197-1.2	V580M	Neutral	0.092
LRP5	O75197-1.2	V580N	Pathogenic	0.639
LRP5	O75197-1.2	V580P	Pathogenic	0.652
LRP5	O75197-1.2	V580Q	Neutral	0.449
LRP5	O75197-1.2	V580R	Pathogenic	0.538
LRP5	O75197-1.2	V580S	Neutral	0.481
LRP5	O75197-1.2	V580T	Neutral	0.119
LRP5	O75197-1.2	V580W	Pathogenic	0.767
LRP5	O75197-1.2	V580Y	Neutral	0.425
LRP5	O75197-1.2	I581A	Pathogenic	0.975
LRP5	O75197-1.2	I581C	Pathogenic	0.987
LRP5	O75197-1.2	I581D	Pathogenic	0.993
LRP5	O75197-1.2	I581E	Pathogenic	0.994
LRP5	O75197-1.2	I581F	Pathogenic	0.981
LRP5	O75197-1.2	I581G	Pathogenic	0.999
LRP5	O75197-1.2	I581H	Pathogenic	0.997
LRP5	O75197-1.2	I581K	Pathogenic	0.992
LRP5	O75197-1.2	I581L	Pathogenic	0.84
LRP5	O75197-1.2	I581M	Pathogenic	0.913
LRP5	O75197-1.2	I581N	Pathogenic	0.994
LRP5	O75197-1.2	I581P	Pathogenic	0.998
LRP5	O75197-1.2	I581Q	Pathogenic	0.996
LRP5	O75197-1.2	I581R	Pathogenic	0.992
LRP5	O75197-1.2	I581S	Pathogenic	0.989
LRP5	O75197-1.2	I581T	Pathogenic	0.975
LRP5	O75197-1.2	I581V	Pathogenic	0.521
LRP5	O75197-1.2	I581W	Pathogenic	0.999
LRP5	O75197-1.2	I581Y	Pathogenic	0.987
LRP5	O75197-1.2	I582A	Pathogenic	0.909
LRP5	O75197-1.2	I582C	Pathogenic	0.949
LRP5	O75197-1.2	I582D	Pathogenic	0.973
LRP5	O75197-1.2	I582E	Pathogenic	0.977
LRP5	O75197-1.2	I582F	Pathogenic	0.93
LRP5	O75197-1.2	I582G	Pathogenic	0.995
LRP5	O75197-1.2	I582H	Pathogenic	0.988
LRP5	O75197-1.2	I582K	Pathogenic	0.969
LRP5	O75197-1.2	I582L	Pathogenic	0.574
LRP5	O75197-1.2	I582M	Pathogenic	0.729
LRP5	O75197-1.2	I582N	Pathogenic	0.977
LRP5	O75197-1.2	I582P	Pathogenic	0.993
LRP5	O75197-1.2	I582Q	Pathogenic	0.984
LRP5	O75197-1.2	I582R	Pathogenic	0.968
LRP5	O75197-1.2	I582S	Pathogenic	0.957
LRP5	O75197-1.2	I582T	Pathogenic	0.908
LRP5	O75197-1.2	I582V	Neutral	0.218
LRP5	O75197-1.2	I582W	Pathogenic	0.996
LRP5	O75197-1.2	I582Y	Pathogenic	0.95
LRP5	O75197-1.2	D583A	Pathogenic	0.987
LRP5	O75197-1.2	D583C	Pathogenic	0.992
LRP5	O75197-1.2	D583E	Pathogenic	0.67
LRP5	O75197-1.2	D583F	Pathogenic	0.983
LRP5	O75197-1.2	D583G	Pathogenic	0.969
LRP5	O75197-1.2	D583H	Pathogenic	0.966
LRP5	O75197-1.2	D583I	Pathogenic	0.983
LRP5	O75197-1.2	D583K	Pathogenic	0.981
LRP5	O75197-1.2	D583L	Pathogenic	0.995
LRP5	O75197-1.2	D583M	Pathogenic	0.99
LRP5	O75197-1.2	D583N	Pathogenic	0.859
LRP5	O75197-1.2	D583P	Pathogenic	0.946
LRP5	O75197-1.2	D583Q	Pathogenic	0.928
LRP5	O75197-1.2	D583R	Pathogenic	0.993
LRP5	O75197-1.2	D583S	Pathogenic	0.916
LRP5	O75197-1.2	D583T	Pathogenic	0.963
LRP5	O75197-1.2	D583V	Pathogenic	0.99
LRP5	O75197-1.2	D583W	Pathogenic	0.991
LRP5	O75197-1.2	D583Y	Pathogenic	0.992
LRP5	O75197-1.2	Q584A	Pathogenic	0.997
LRP5	O75197-1.2	Q584C	Pathogenic	0.999
LRP5	O75197-1.2	Q584D	Pathogenic	0.99
LRP5	O75197-1.2	Q584E	Pathogenic	0.923
LRP5	O75197-1.2	Q584F	Pathogenic	0.999
LRP5	O75197-1.2	Q584G	Pathogenic	0.999
LRP5	O75197-1.2	Q584H	Pathogenic	0.992
LRP5	O75197-1.2	Q584I	Pathogenic	0.999
LRP5	O75197-1.2	Q584K	Pathogenic	0.963
LRP5	O75197-1.2	Q584L	Pathogenic	0.996
LRP5	O75197-1.2	Q584M	Pathogenic	0.978
LRP5	O75197-1.2	Q584N	Pathogenic	0.991
LRP5	O75197-1.2	Q584P	Pathogenic	0.995
LRP5	O75197-1.2	Q584R	Pathogenic	0.962
LRP5	O75197-1.2	Q584S	Pathogenic	0.992
LRP5	O75197-1.2	Q584T	Pathogenic	0.997
LRP5	O75197-1.2	Q584V	Pathogenic	0.998
LRP5	O75197-1.2	Q584W	Pathogenic	0.994
LRP5	O75197-1.2	Q584Y	Pathogenic	0.994
LRP5	O75197-1.2	L585A	Pathogenic	0.922
LRP5	O75197-1.2	L585C	Pathogenic	0.957
LRP5	O75197-1.2	L585D	Pathogenic	0.993
LRP5	O75197-1.2	L585E	Pathogenic	0.981
LRP5	O75197-1.2	L585F	Pathogenic	0.931
LRP5	O75197-1.2	L585G	Pathogenic	0.996
LRP5	O75197-1.2	L585H	Pathogenic	0.99
LRP5	O75197-1.2	L585I	Pathogenic	0.595
LRP5	O75197-1.2	L585K	Pathogenic	0.924
LRP5	O75197-1.2	L585M	Pathogenic	0.514
LRP5	O75197-1.2	L585N	Pathogenic	0.981
LRP5	O75197-1.2	L585P	Pathogenic	0.994
LRP5	O75197-1.2	L585Q	Pathogenic	0.961
LRP5	O75197-1.2	L585R	Pathogenic	0.922
LRP5	O75197-1.2	L585S	Pathogenic	0.964
LRP5	O75197-1.2	L585T	Pathogenic	0.922
LRP5	O75197-1.2	L585V	Pathogenic	0.755
LRP5	O75197-1.2	L585W	Pathogenic	0.988
LRP5	O75197-1.2	L585Y	Pathogenic	0.958
LRP5	O75197-1.2	P586A	Pathogenic	0.995
LRP5	O75197-1.2	P586C	Pathogenic	1.0
LRP5	O75197-1.2	P586D	Pathogenic	0.987
LRP5	O75197-1.2	P586E	Pathogenic	0.988
LRP5	O75197-1.2	P586F	Pathogenic	1.0
LRP5	O75197-1.2	P586G	Pathogenic	0.998
LRP5	O75197-1.2	P586H	Pathogenic	0.998
LRP5	O75197-1.2	P586I	Pathogenic	0.999
LRP5	O75197-1.2	P586K	Pathogenic	0.983
LRP5	O75197-1.2	P586L	Pathogenic	0.999
LRP5	O75197-1.2	P586M	Pathogenic	0.998
LRP5	O75197-1.2	P586N	Pathogenic	0.996
LRP5	O75197-1.2	P586Q	Pathogenic	0.992
LRP5	O75197-1.2	P586R	Pathogenic	0.994
LRP5	O75197-1.2	P586S	Pathogenic	0.993
LRP5	O75197-1.2	P586T	Pathogenic	0.995
LRP5	O75197-1.2	P586V	Pathogenic	0.998
LRP5	O75197-1.2	P586W	Pathogenic	0.999
LRP5	O75197-1.2	P586Y	Pathogenic	1.0
LRP5	O75197-1.2	D587A	Pathogenic	0.985
LRP5	O75197-1.2	D587C	Pathogenic	0.991
LRP5	O75197-1.2	D587E	Pathogenic	0.65
LRP5	O75197-1.2	D587F	Pathogenic	0.982
LRP5	O75197-1.2	D587G	Pathogenic	0.966
LRP5	O75197-1.2	D587H	Pathogenic	0.963
LRP5	O75197-1.2	D587I	Pathogenic	0.982
LRP5	O75197-1.2	D587K	Pathogenic	0.979
LRP5	O75197-1.2	D587L	Pathogenic	0.994
LRP5	O75197-1.2	D587M	Pathogenic	0.989
LRP5	O75197-1.2	D587N	Pathogenic	0.848
LRP5	O75197-1.2	D587P	Pathogenic	0.941
LRP5	O75197-1.2	D587Q	Pathogenic	0.922
LRP5	O75197-1.2	D587R	Pathogenic	0.993
LRP5	O75197-1.2	D587S	Pathogenic	0.91
LRP5	O75197-1.2	D587T	Pathogenic	0.96
LRP5	O75197-1.2	D587V	Pathogenic	0.989
LRP5	O75197-1.2	D587W	Pathogenic	0.99
LRP5	O75197-1.2	D587Y	Pathogenic	0.991
LRP5	O75197-1.2	L588A	Pathogenic	0.922
LRP5	O75197-1.2	L588C	Pathogenic	0.957
LRP5	O75197-1.2	L588D	Pathogenic	0.993
LRP5	O75197-1.2	L588E	Pathogenic	0.981
LRP5	O75197-1.2	L588F	Pathogenic	0.931
LRP5	O75197-1.2	L588G	Pathogenic	0.996
LRP5	O75197-1.2	L588H	Pathogenic	0.99
LRP5	O75197-1.2	L588I	Pathogenic	0.595
LRP5	O75197-1.2	L588K	Pathogenic	0.924
LRP5	O75197-1.2	L588M	Pathogenic	0.514
LRP5	O75197-1.2	L588N	Pathogenic	0.981
LRP5	O75197-1.2	L588P	Pathogenic	0.994
LRP5	O75197-1.2	L588Q	Pathogenic	0.961
LRP5	O75197-1.2	L588R	Pathogenic	0.922
LRP5	O75197-1.2	L588S	Pathogenic	0.964
LRP5	O75197-1.2	L588T	Pathogenic	0.922
LRP5	O75197-1.2	L588V	Pathogenic	0.755
LRP5	O75197-1.2	L588W	Pathogenic	0.988
LRP5	O75197-1.2	L588Y	Pathogenic	0.958
LRP5	O75197-1.2	M589A	Pathogenic	0.996
LRP5	O75197-1.2	M589C	Pathogenic	0.998
LRP5	O75197-1.2	M589D	Pathogenic	0.999
LRP5	O75197-1.2	M589E	Pathogenic	0.997
LRP5	O75197-1.2	M589F	Pathogenic	0.993
LRP5	O75197-1.2	M589G	Pathogenic	0.999
LRP5	O75197-1.2	M589H	Pathogenic	0.999
LRP5	O75197-1.2	M589I	Pathogenic	0.978
LRP5	O75197-1.2	M589K	Pathogenic	0.989
LRP5	O75197-1.2	M589L	Pathogenic	0.941
LRP5	O75197-1.2	M589N	Pathogenic	0.997
LRP5	O75197-1.2	M589P	Pathogenic	0.999
LRP5	O75197-1.2	M589Q	Pathogenic	0.984
LRP5	O75197-1.2	M589R	Pathogenic	0.989
LRP5	O75197-1.2	M589S	Pathogenic	0.995
LRP5	O75197-1.2	M589T	Pathogenic	0.996
LRP5	O75197-1.2	M589V	Pathogenic	0.986
LRP5	O75197-1.2	M589W	Pathogenic	0.996
LRP5	O75197-1.2	M589Y	Pathogenic	0.998
LRP5	O75197-1.2	G590A	Pathogenic	0.98
LRP5	O75197-1.2	G590C	Pathogenic	0.999
LRP5	O75197-1.2	G590D	Pathogenic	0.989
LRP5	O75197-1.2	G590E	Pathogenic	0.997
LRP5	O75197-1.2	G590F	Pathogenic	0.997
LRP5	O75197-1.2	G590H	Pathogenic	0.998
LRP5	O75197-1.2	G590I	Pathogenic	0.999
LRP5	O75197-1.2	G590K	Pathogenic	0.995
LRP5	O75197-1.2	G590L	Pathogenic	0.999
LRP5	O75197-1.2	G590M	Pathogenic	0.998
LRP5	O75197-1.2	G590N	Pathogenic	0.973
LRP5	O75197-1.2	G590P	Pathogenic	0.997
LRP5	O75197-1.2	G590Q	Pathogenic	0.998
LRP5	O75197-1.2	G590R	Pathogenic	0.995
LRP5	O75197-1.2	G590S	Pathogenic	0.984
LRP5	O75197-1.2	G590T	Pathogenic	0.998
LRP5	O75197-1.2	G590V	Pathogenic	0.998
LRP5	O75197-1.2	G590W	Pathogenic	0.985
LRP5	O75197-1.2	G590Y	Pathogenic	0.999
LRP5	O75197-1.2	L591A	Pathogenic	0.959
LRP5	O75197-1.2	L591C	Pathogenic	0.978
LRP5	O75197-1.2	L591D	Pathogenic	0.996
LRP5	O75197-1.2	L591E	Pathogenic	0.99
LRP5	O75197-1.2	L591F	Pathogenic	0.963
LRP5	O75197-1.2	L591G	Pathogenic	0.998
LRP5	O75197-1.2	L591H	Pathogenic	0.995
LRP5	O75197-1.2	L591I	Pathogenic	0.741
LRP5	O75197-1.2	L591K	Pathogenic	0.96
LRP5	O75197-1.2	L591M	Pathogenic	0.673
LRP5	O75197-1.2	L591N	Pathogenic	0.99
LRP5	O75197-1.2	L591P	Pathogenic	0.997
LRP5	O75197-1.2	L591Q	Pathogenic	0.979
LRP5	O75197-1.2	L591R	Pathogenic	0.958
LRP5	O75197-1.2	L591S	Pathogenic	0.981
LRP5	O75197-1.2	L591T	Pathogenic	0.959
LRP5	O75197-1.2	L591V	Pathogenic	0.857
LRP5	O75197-1.2	L591W	Pathogenic	0.994
LRP5	O75197-1.2	L591Y	Pathogenic	0.978
LRP5	O75197-1.2	K592A	Pathogenic	0.993
LRP5	O75197-1.2	K592C	Pathogenic	0.999
LRP5	O75197-1.2	K592D	Pathogenic	0.997
LRP5	O75197-1.2	K592E	Pathogenic	0.973
LRP5	O75197-1.2	K592F	Pathogenic	0.997
LRP5	O75197-1.2	K592G	Pathogenic	0.998
LRP5	O75197-1.2	K592H	Pathogenic	0.994
LRP5	O75197-1.2	K592I	Pathogenic	0.997
LRP5	O75197-1.2	K592L	Pathogenic	0.992
LRP5	O75197-1.2	K592M	Pathogenic	0.985
LRP5	O75197-1.2	K592N	Pathogenic	0.991
LRP5	O75197-1.2	K592P	Pathogenic	0.99
LRP5	O75197-1.2	K592Q	Pathogenic	0.962
LRP5	O75197-1.2	K592R	Pathogenic	0.943
LRP5	O75197-1.2	K592S	Pathogenic	0.984
LRP5	O75197-1.2	K592T	Pathogenic	0.993
LRP5	O75197-1.2	K592V	Pathogenic	0.995
LRP5	O75197-1.2	K592W	Pathogenic	0.996
LRP5	O75197-1.2	K592Y	Pathogenic	0.996
LRP5	O75197-1.2	A593C	Pathogenic	0.981
LRP5	O75197-1.2	A593D	Pathogenic	0.997
LRP5	O75197-1.2	A593E	Pathogenic	0.991
LRP5	O75197-1.2	A593F	Pathogenic	0.995
LRP5	O75197-1.2	A593G	Pathogenic	0.986
LRP5	O75197-1.2	A593H	Pathogenic	0.999
LRP5	O75197-1.2	A593I	Pathogenic	0.986
LRP5	O75197-1.2	A593K	Pathogenic	0.988
LRP5	O75197-1.2	A593L	Pathogenic	0.987
LRP5	O75197-1.2	A593M	Pathogenic	0.991
LRP5	O75197-1.2	A593N	Pathogenic	0.997
LRP5	O75197-1.2	A593P	Pathogenic	0.995
LRP5	O75197-1.2	A593Q	Pathogenic	0.994
LRP5	O75197-1.2	A593R	Pathogenic	0.987
LRP5	O75197-1.2	A593S	Pathogenic	0.958
LRP5	O75197-1.2	A593T	Pathogenic	0.989
LRP5	O75197-1.2	A593V	Pathogenic	0.976
LRP5	O75197-1.2	A593W	Pathogenic	0.998
LRP5	O75197-1.2	A593Y	Pathogenic	0.998
LRP5	O75197-1.2	V594A	Neutral	0.049
LRP5	O75197-1.2	V594C	Neutral	0.228
LRP5	O75197-1.2	V594D	Neutral	0.365
LRP5	O75197-1.2	V594E	Neutral	0.177
LRP5	O75197-1.2	V594F	Neutral	0.176
LRP5	O75197-1.2	V594G	Pathogenic	0.516
LRP5	O75197-1.2	V594H	Pathogenic	0.563
LRP5	O75197-1.2	V594I	Neutral	0.003
LRP5	O75197-1.2	V594K	Neutral	0.131
LRP5	O75197-1.2	V594L	Neutral	0.025
LRP5	O75197-1.2	V594M	Neutral	0.037
LRP5	O75197-1.2	V594N	Neutral	0.402
LRP5	O75197-1.2	V594P	Neutral	0.416
LRP5	O75197-1.2	V594Q	Neutral	0.237
LRP5	O75197-1.2	V594R	Neutral	0.308
LRP5	O75197-1.2	V594S	Neutral	0.261
LRP5	O75197-1.2	V594T	Neutral	0.049
LRP5	O75197-1.2	V594W	Pathogenic	0.556
LRP5	O75197-1.2	V594Y	Neutral	0.22
LRP5	O75197-1.2	N595A	Pathogenic	0.651
LRP5	O75197-1.2	N595C	Pathogenic	0.762
LRP5	O75197-1.2	N595D	Neutral	0.118
LRP5	O75197-1.2	N595E	Neutral	0.311
LRP5	O75197-1.2	N595F	Pathogenic	0.598
LRP5	O75197-1.2	N595G	Neutral	0.205
LRP5	O75197-1.2	N595H	Neutral	0.073
LRP5	O75197-1.2	N595I	Pathogenic	0.599
LRP5	O75197-1.2	N595K	Neutral	0.24
LRP5	O75197-1.2	N595L	Pathogenic	0.621
LRP5	O75197-1.2	N595M	Neutral	0.45
LRP5	O75197-1.2	N595P	Pathogenic	0.573
LRP5	O75197-1.2	N595Q	Neutral	0.248
LRP5	O75197-1.2	N595R	Neutral	0.234
LRP5	O75197-1.2	N595S	Neutral	0.084
LRP5	O75197-1.2	N595T	Neutral	0.181
LRP5	O75197-1.2	N595V	Pathogenic	0.722
LRP5	O75197-1.2	N595W	Pathogenic	0.741
LRP5	O75197-1.2	N595Y	Pathogenic	0.504
LRP5	O75197-1.2	V596A	Pathogenic	0.819
LRP5	O75197-1.2	V596C	Pathogenic	0.963
LRP5	O75197-1.2	V596D	Pathogenic	0.981
LRP5	O75197-1.2	V596E	Pathogenic	0.95
LRP5	O75197-1.2	V596F	Pathogenic	0.95
LRP5	O75197-1.2	V596G	Pathogenic	0.989
LRP5	O75197-1.2	V596H	Pathogenic	0.991
LRP5	O75197-1.2	V596I	Neutral	0.181
LRP5	O75197-1.2	V596K	Pathogenic	0.93
LRP5	O75197-1.2	V596L	Pathogenic	0.691
LRP5	O75197-1.2	V596M	Pathogenic	0.773
LRP5	O75197-1.2	V596N	Pathogenic	0.983
LRP5	O75197-1.2	V596P	Pathogenic	0.984
LRP5	O75197-1.2	V596Q	Pathogenic	0.965
LRP5	O75197-1.2	V596R	Pathogenic	0.975
LRP5	O75197-1.2	V596S	Pathogenic	0.969
LRP5	O75197-1.2	V596T	Pathogenic	0.818
LRP5	O75197-1.2	V596W	Pathogenic	0.991
LRP5	O75197-1.2	V596Y	Pathogenic	0.961
LRP5	O75197-1.2	A597C	Neutral	0.006
LRP5	O75197-1.2	A597D	Neutral	0.037
LRP5	O75197-1.2	A597E	Neutral	0.014
LRP5	O75197-1.2	A597F	Neutral	0.024
LRP5	O75197-1.2	A597G	Neutral	0.008
LRP5	O75197-1.2	A597H	Neutral	0.076
LRP5	O75197-1.2	A597I	Neutral	0.008
LRP5	O75197-1.2	A597K	Neutral	0.01
LRP5	O75197-1.2	A597L	Neutral	0.009
LRP5	O75197-1.2	A597M	Neutral	0.013
LRP5	O75197-1.2	A597N	Neutral	0.042
LRP5	O75197-1.2	A597P	Neutral	0.022
LRP5	O75197-1.2	A597Q	Neutral	0.019
LRP5	O75197-1.2	A597R	Neutral	0.009
LRP5	O75197-1.2	A597S	Neutral	0.003
LRP5	O75197-1.2	A597T	Neutral	0.01
LRP5	O75197-1.2	A597V	Neutral	0.005
LRP5	O75197-1.2	A597W	Neutral	0.046
LRP5	O75197-1.2	A597Y	Neutral	0.049
LRP5	O75197-1.2	K598A	Neutral	0.113
LRP5	O75197-1.2	K598C	Neutral	0.401
LRP5	O75197-1.2	K598D	Neutral	0.259
LRP5	O75197-1.2	K598E	Neutral	0.033
LRP5	O75197-1.2	K598F	Neutral	0.26
LRP5	O75197-1.2	K598G	Neutral	0.332
LRP5	O75197-1.2	K598H	Neutral	0.14
LRP5	O75197-1.2	K598I	Neutral	0.254
LRP5	O75197-1.2	K598L	Neutral	0.109
LRP5	O75197-1.2	K598M	Neutral	0.058
LRP5	O75197-1.2	K598N	Neutral	0.09
LRP5	O75197-1.2	K598P	Neutral	0.084
LRP5	O75197-1.2	K598Q	Neutral	0.023
LRP5	O75197-1.2	K598R	Neutral	0.015
LRP5	O75197-1.2	K598S	Neutral	0.055
LRP5	O75197-1.2	K598T	Neutral	0.123
LRP5	O75197-1.2	K598V	Neutral	0.155
LRP5	O75197-1.2	K598W	Neutral	0.182
LRP5	O75197-1.2	K598Y	Neutral	0.194
LRP5	O75197-1.2	V599A	Neutral	0.074
LRP5	O75197-1.2	V599C	Neutral	0.314
LRP5	O75197-1.2	V599D	Neutral	0.472
LRP5	O75197-1.2	V599E	Neutral	0.251
LRP5	O75197-1.2	V599F	Neutral	0.25
LRP5	O75197-1.2	V599G	Pathogenic	0.624
LRP5	O75197-1.2	V599H	Pathogenic	0.667
LRP5	O75197-1.2	V599I	Neutral	0.004
LRP5	O75197-1.2	V599K	Neutral	0.19
LRP5	O75197-1.2	V599L	Neutral	0.038
LRP5	O75197-1.2	V599M	Neutral	0.057
LRP5	O75197-1.2	V599N	Pathogenic	0.511
LRP5	O75197-1.2	V599P	Pathogenic	0.526
LRP5	O75197-1.2	V599Q	Neutral	0.326
LRP5	O75197-1.2	V599R	Neutral	0.409
LRP5	O75197-1.2	V599S	Neutral	0.355
LRP5	O75197-1.2	V599T	Neutral	0.074
LRP5	O75197-1.2	V599W	Pathogenic	0.661
LRP5	O75197-1.2	V599Y	Neutral	0.304
LRP5	O75197-1.2	V600A	Neutral	0.001
LRP5	O75197-1.2	V600C	Neutral	0.005
LRP5	O75197-1.2	V600D	Neutral	0.01
LRP5	O75197-1.2	V600E	Neutral	0.004
LRP5	O75197-1.2	V600F	Neutral	0.004
LRP5	O75197-1.2	V600G	Neutral	0.019
LRP5	O75197-1.2	V600H	Neutral	0.022
LRP5	O75197-1.2	V600I	Neutral	0.0
LRP5	O75197-1.2	V600K	Neutral	0.003
LRP5	O75197-1.2	V600L	Neutral	0.0
LRP5	O75197-1.2	V600M	Neutral	0.001
LRP5	O75197-1.2	V600N	Neutral	0.012
LRP5	O75197-1.2	V600P	Neutral	0.012
LRP5	O75197-1.2	V600Q	Neutral	0.005
LRP5	O75197-1.2	V600R	Neutral	0.008
LRP5	O75197-1.2	V600S	Neutral	0.006
LRP5	O75197-1.2	V600T	Neutral	0.001
LRP5	O75197-1.2	V600W	Neutral	0.022
LRP5	O75197-1.2	V600Y	Neutral	0.005
LRP5	O75197-1.2	G601A	Pathogenic	0.962
LRP5	O75197-1.2	G601C	Pathogenic	0.997
LRP5	O75197-1.2	G601D	Pathogenic	0.98
LRP5	O75197-1.2	G601E	Pathogenic	0.994
LRP5	O75197-1.2	G601F	Pathogenic	0.994
LRP5	O75197-1.2	G601H	Pathogenic	0.996
LRP5	O75197-1.2	G601I	Pathogenic	0.998
LRP5	O75197-1.2	G601K	Pathogenic	0.991
LRP5	O75197-1.2	G601L	Pathogenic	0.998
LRP5	O75197-1.2	G601M	Pathogenic	0.996
LRP5	O75197-1.2	G601N	Pathogenic	0.949
LRP5	O75197-1.2	G601P	Pathogenic	0.994
LRP5	O75197-1.2	G601Q	Pathogenic	0.996
LRP5	O75197-1.2	G601R	Pathogenic	0.991
LRP5	O75197-1.2	G601S	Pathogenic	0.969
LRP5	O75197-1.2	G601T	Pathogenic	0.996
LRP5	O75197-1.2	G601V	Pathogenic	0.997
LRP5	O75197-1.2	G601W	Pathogenic	0.972
LRP5	O75197-1.2	G601Y	Pathogenic	0.997
LRP5	O75197-1.2	T602A	Pathogenic	0.665
LRP5	O75197-1.2	T602C	Pathogenic	0.773
LRP5	O75197-1.2	T602D	Pathogenic	0.724
LRP5	O75197-1.2	T602E	Pathogenic	0.742
LRP5	O75197-1.2	T602F	Pathogenic	0.826
LRP5	O75197-1.2	T602G	Pathogenic	0.937
LRP5	O75197-1.2	T602H	Pathogenic	0.945
LRP5	O75197-1.2	T602I	Pathogenic	0.611
LRP5	O75197-1.2	T602K	Pathogenic	0.669
LRP5	O75197-1.2	T602L	Pathogenic	0.632
LRP5	O75197-1.2	T602M	Pathogenic	0.724
LRP5	O75197-1.2	T602N	Neutral	0.5
LRP5	O75197-1.2	T602P	Pathogenic	0.812
LRP5	O75197-1.2	T602Q	Pathogenic	0.806
LRP5	O75197-1.2	T602R	Pathogenic	0.661
LRP5	O75197-1.2	T602S	Neutral	0.346
LRP5	O75197-1.2	T602V	Neutral	0.473
LRP5	O75197-1.2	T602W	Pathogenic	0.75
LRP5	O75197-1.2	T602Y	Pathogenic	0.908
LRP5	O75197-1.2	N603A	Neutral	0.328
LRP5	O75197-1.2	N603C	Neutral	0.456
LRP5	O75197-1.2	N603D	Neutral	0.034
LRP5	O75197-1.2	N603E	Neutral	0.106
LRP5	O75197-1.2	N603F	Neutral	0.28
LRP5	O75197-1.2	N603G	Neutral	0.063
LRP5	O75197-1.2	N603H	Neutral	0.02
LRP5	O75197-1.2	N603I	Neutral	0.281
LRP5	O75197-1.2	N603K	Neutral	0.076
LRP5	O75197-1.2	N603L	Neutral	0.3
LRP5	O75197-1.2	N603M	Neutral	0.177
LRP5	O75197-1.2	N603P	Neutral	0.26
LRP5	O75197-1.2	N603Q	Neutral	0.079
LRP5	O75197-1.2	N603R	Neutral	0.074
LRP5	O75197-1.2	N603S	Neutral	0.023
LRP5	O75197-1.2	N603T	Neutral	0.055
LRP5	O75197-1.2	N603V	Neutral	0.405
LRP5	O75197-1.2	N603W	Neutral	0.428
LRP5	O75197-1.2	N603Y	Neutral	0.21
LRP5	O75197-1.2	P604A	Neutral	0.008
LRP5	O75197-1.2	P604C	Neutral	0.084
LRP5	O75197-1.2	P604D	Neutral	0.003
LRP5	O75197-1.2	P604E	Neutral	0.004
LRP5	O75197-1.2	P604F	Neutral	0.113
LRP5	O75197-1.2	P604G	Neutral	0.019
LRP5	O75197-1.2	P604H	Neutral	0.021
LRP5	O75197-1.2	P604I	Neutral	0.04
LRP5	O75197-1.2	P604K	Neutral	0.003
LRP5	O75197-1.2	P604L	Neutral	0.044
LRP5	O75197-1.2	P604M	Neutral	0.022
LRP5	O75197-1.2	P604N	Neutral	0.012
LRP5	O75197-1.2	P604Q	Neutral	0.005
LRP5	O75197-1.2	P604R	Neutral	0.007
LRP5	O75197-1.2	P604S	Neutral	0.006
LRP5	O75197-1.2	P604T	Neutral	0.008
LRP5	O75197-1.2	P604V	Neutral	0.023
LRP5	O75197-1.2	P604W	Neutral	0.074
LRP5	O75197-1.2	P604Y	Neutral	0.08
LRP5	O75197-1.2	C605A	Pathogenic	0.992
LRP5	O75197-1.2	C605D	Pathogenic	0.999
LRP5	O75197-1.2	C605E	Pathogenic	1.0
LRP5	O75197-1.2	C605F	Pathogenic	0.999
LRP5	O75197-1.2	C605G	Pathogenic	1.0
LRP5	O75197-1.2	C605H	Pathogenic	1.0
LRP5	O75197-1.2	C605I	Pathogenic	0.997
LRP5	O75197-1.2	C605K	Pathogenic	0.999
LRP5	O75197-1.2	C605L	Pathogenic	0.997
LRP5	O75197-1.2	C605M	Pathogenic	0.998
LRP5	O75197-1.2	C605N	Pathogenic	0.999
LRP5	O75197-1.2	C605P	Pathogenic	1.0
LRP5	O75197-1.2	C605Q	Pathogenic	1.0
LRP5	O75197-1.2	C605R	Pathogenic	0.999
LRP5	O75197-1.2	C605S	Pathogenic	0.997
LRP5	O75197-1.2	C605T	Pathogenic	0.997
LRP5	O75197-1.2	C605V	Pathogenic	0.998
LRP5	O75197-1.2	C605W	Pathogenic	0.998
LRP5	O75197-1.2	C605Y	Pathogenic	0.999
LRP5	O75197-1.2	A606C	Neutral	0.003
LRP5	O75197-1.2	A606D	Neutral	0.02
LRP5	O75197-1.2	A606E	Neutral	0.007
LRP5	O75197-1.2	A606F	Neutral	0.013
LRP5	O75197-1.2	A606G	Neutral	0.004
LRP5	O75197-1.2	A606H	Neutral	0.042
LRP5	O75197-1.2	A606I	Neutral	0.004
LRP5	O75197-1.2	A606K	Neutral	0.005
LRP5	O75197-1.2	A606L	Neutral	0.005
LRP5	O75197-1.2	A606M	Neutral	0.007
LRP5	O75197-1.2	A606N	Neutral	0.023
LRP5	O75197-1.2	A606P	Neutral	0.012
LRP5	O75197-1.2	A606Q	Neutral	0.01
LRP5	O75197-1.2	A606R	Neutral	0.005
LRP5	O75197-1.2	A606S	Neutral	0.001
LRP5	O75197-1.2	A606T	Neutral	0.005
LRP5	O75197-1.2	A606V	Neutral	0.002
LRP5	O75197-1.2	A606W	Neutral	0.025
LRP5	O75197-1.2	A606Y	Neutral	0.027
LRP5	O75197-1.2	D607A	Neutral	0.0
LRP5	O75197-1.2	D607C	Neutral	0.0
LRP5	O75197-1.2	D607E	Neutral	0.0
LRP5	O75197-1.2	D607F	Neutral	0.0
LRP5	O75197-1.2	D607G	Neutral	0.0
LRP5	O75197-1.2	D607H	Neutral	0.0
LRP5	O75197-1.2	D607I	Neutral	0.0
LRP5	O75197-1.2	D607K	Neutral	0.0
LRP5	O75197-1.2	D607L	Neutral	0.0
LRP5	O75197-1.2	D607M	Neutral	0.0
LRP5	O75197-1.2	D607N	Neutral	0.0
LRP5	O75197-1.2	D607P	Neutral	0.0
LRP5	O75197-1.2	D607Q	Neutral	0.0
LRP5	O75197-1.2	D607R	Neutral	0.0
LRP5	O75197-1.2	D607S	Neutral	0.0
LRP5	O75197-1.2	D607T	Neutral	0.0
LRP5	O75197-1.2	D607V	Neutral	0.0
LRP5	O75197-1.2	D607W	Neutral	0.0
LRP5	O75197-1.2	D607Y	Neutral	0.0
LRP5	O75197-1.2	R608A	Neutral	0.0
LRP5	O75197-1.2	R608C	Neutral	0.0
LRP5	O75197-1.2	R608D	Neutral	0.0
LRP5	O75197-1.2	R608E	Neutral	0.0
LRP5	O75197-1.2	R608F	Neutral	0.0
LRP5	O75197-1.2	R608G	Neutral	0.0
LRP5	O75197-1.2	R608H	Neutral	0.0
LRP5	O75197-1.2	R608I	Neutral	0.0
LRP5	O75197-1.2	R608K	Neutral	0.0
LRP5	O75197-1.2	R608L	Neutral	0.0
LRP5	O75197-1.2	R608M	Neutral	0.0
LRP5	O75197-1.2	R608N	Neutral	0.0
LRP5	O75197-1.2	R608P	Neutral	0.0
LRP5	O75197-1.2	R608Q	Neutral	0.0
LRP5	O75197-1.2	R608S	Neutral	0.0
LRP5	O75197-1.2	R608T	Neutral	0.0
LRP5	O75197-1.2	R608V	Neutral	0.0
LRP5	O75197-1.2	R608W	Neutral	0.0
LRP5	O75197-1.2	R608Y	Neutral	0.0
LRP5	O75197-1.2	N609A	Pathogenic	0.554
LRP5	O75197-1.2	N609C	Pathogenic	0.681
LRP5	O75197-1.2	N609D	Neutral	0.082
LRP5	O75197-1.2	N609E	Neutral	0.231
LRP5	O75197-1.2	N609F	Neutral	0.497
LRP5	O75197-1.2	N609G	Neutral	0.146
LRP5	O75197-1.2	N609H	Neutral	0.05
LRP5	O75197-1.2	N609I	Neutral	0.498
LRP5	O75197-1.2	N609K	Neutral	0.174
LRP5	O75197-1.2	N609L	Pathogenic	0.521
LRP5	O75197-1.2	N609M	Neutral	0.353
LRP5	O75197-1.2	N609P	Neutral	0.472
LRP5	O75197-1.2	N609Q	Neutral	0.18
LRP5	O75197-1.2	N609R	Neutral	0.169
LRP5	O75197-1.2	N609S	Neutral	0.057
LRP5	O75197-1.2	N609T	Neutral	0.128
LRP5	O75197-1.2	N609V	Pathogenic	0.634
LRP5	O75197-1.2	N609W	Pathogenic	0.656
LRP5	O75197-1.2	N609Y	Neutral	0.403
LRP5	O75197-1.2	G610A	Neutral	0.114
LRP5	O75197-1.2	G610C	Pathogenic	0.659
LRP5	O75197-1.2	G610D	Neutral	0.2
LRP5	O75197-1.2	G610E	Neutral	0.454
LRP5	O75197-1.2	G610F	Neutral	0.464
LRP5	O75197-1.2	G610H	Pathogenic	0.563
LRP5	O75197-1.2	G610I	Pathogenic	0.726
LRP5	O75197-1.2	G610K	Neutral	0.368
LRP5	O75197-1.2	G610L	Pathogenic	0.744
LRP5	O75197-1.2	G610M	Pathogenic	0.592
LRP5	O75197-1.2	G610N	Neutral	0.087
LRP5	O75197-1.2	G610P	Neutral	0.444
LRP5	O75197-1.2	G610Q	Pathogenic	0.545
LRP5	O75197-1.2	G610R	Neutral	0.36
LRP5	O75197-1.2	G610S	Neutral	0.14
LRP5	O75197-1.2	G610T	Pathogenic	0.546
LRP5	O75197-1.2	G610V	Pathogenic	0.603
LRP5	O75197-1.2	G610W	Neutral	0.153
LRP5	O75197-1.2	G610Y	Pathogenic	0.643
LRP5	O75197-1.2	G611A	Neutral	0.049
LRP5	O75197-1.2	G611C	Neutral	0.433
LRP5	O75197-1.2	G611D	Neutral	0.09
LRP5	O75197-1.2	G611E	Neutral	0.248
LRP5	O75197-1.2	G611F	Neutral	0.256
LRP5	O75197-1.2	G611H	Neutral	0.338
LRP5	O75197-1.2	G611I	Pathogenic	0.512
LRP5	O75197-1.2	G611K	Neutral	0.187
LRP5	O75197-1.2	G611L	Pathogenic	0.535
LRP5	O75197-1.2	G611M	Neutral	0.365
LRP5	O75197-1.2	G611N	Neutral	0.036
LRP5	O75197-1.2	G611P	Neutral	0.24
LRP5	O75197-1.2	G611Q	Neutral	0.322
LRP5	O75197-1.2	G611R	Neutral	0.182
LRP5	O75197-1.2	G611S	Neutral	0.061
LRP5	O75197-1.2	G611T	Neutral	0.322
LRP5	O75197-1.2	G611V	Neutral	0.375
LRP5	O75197-1.2	G611W	Neutral	0.067
LRP5	O75197-1.2	G611Y	Neutral	0.416
LRP5	O75197-1.2	C612A	Pathogenic	0.993
LRP5	O75197-1.2	C612D	Pathogenic	0.999
LRP5	O75197-1.2	C612E	Pathogenic	1.0
LRP5	O75197-1.2	C612F	Pathogenic	0.999
LRP5	O75197-1.2	C612G	Pathogenic	1.0
LRP5	O75197-1.2	C612H	Pathogenic	1.0
LRP5	O75197-1.2	C612I	Pathogenic	0.997
LRP5	O75197-1.2	C612K	Pathogenic	0.999
LRP5	O75197-1.2	C612L	Pathogenic	0.997
LRP5	O75197-1.2	C612M	Pathogenic	0.998
LRP5	O75197-1.2	C612N	Pathogenic	0.999
LRP5	O75197-1.2	C612P	Pathogenic	1.0
LRP5	O75197-1.2	C612Q	Pathogenic	1.0
LRP5	O75197-1.2	C612R	Pathogenic	0.999
LRP5	O75197-1.2	C612S	Pathogenic	0.997
LRP5	O75197-1.2	C612T	Pathogenic	0.998
LRP5	O75197-1.2	C612V	Pathogenic	0.998
LRP5	O75197-1.2	C612W	Pathogenic	0.999
LRP5	O75197-1.2	C612Y	Pathogenic	1.0
LRP5	O75197-1.2	S613A	Neutral	0.024
LRP5	O75197-1.2	S613C	Neutral	0.111
LRP5	O75197-1.2	S613D	Neutral	0.05
LRP5	O75197-1.2	S613E	Neutral	0.054
LRP5	O75197-1.2	S613F	Neutral	0.146
LRP5	O75197-1.2	S613G	Neutral	0.088
LRP5	O75197-1.2	S613H	Neutral	0.202
LRP5	O75197-1.2	S613I	Neutral	0.146
LRP5	O75197-1.2	S613K	Neutral	0.039
LRP5	O75197-1.2	S613L	Neutral	0.158
LRP5	O75197-1.2	S613M	Neutral	0.086
LRP5	O75197-1.2	S613N	Neutral	0.02
LRP5	O75197-1.2	S613P	Neutral	0.136
LRP5	O75197-1.2	S613Q	Neutral	0.076
LRP5	O75197-1.2	S613R	Neutral	0.106
LRP5	O75197-1.2	S613T	Neutral	0.025
LRP5	O75197-1.2	S613V	Neutral	0.23
LRP5	O75197-1.2	S613W	Neutral	0.247
LRP5	O75197-1.2	S613Y	Neutral	0.262
LRP5	O75197-1.2	H614A	Pathogenic	0.822
LRP5	O75197-1.2	H614C	Pathogenic	0.888
LRP5	O75197-1.2	H614D	Neutral	0.452
LRP5	O75197-1.2	H614E	Neutral	0.239
LRP5	O75197-1.2	H614F	Neutral	0.299
LRP5	O75197-1.2	H614G	Pathogenic	0.823
LRP5	O75197-1.2	H614I	Pathogenic	0.799
LRP5	O75197-1.2	H614K	Neutral	0.408
LRP5	O75197-1.2	H614L	Pathogenic	0.813
LRP5	O75197-1.2	H614M	Pathogenic	0.685
LRP5	O75197-1.2	H614N	Neutral	0.095
LRP5	O75197-1.2	H614P	Pathogenic	0.769
LRP5	O75197-1.2	H614Q	Neutral	0.315
LRP5	O75197-1.2	H614R	Neutral	0.18
LRP5	O75197-1.2	H614S	Pathogenic	0.607
LRP5	O75197-1.2	H614T	Pathogenic	0.835
LRP5	O75197-1.2	H614V	Pathogenic	0.869
LRP5	O75197-1.2	H614W	Neutral	0.451
LRP5	O75197-1.2	H614Y	Neutral	0.031
LRP5	O75197-1.2	L615A	Neutral	0.097
LRP5	O75197-1.2	L615C	Neutral	0.169
LRP5	O75197-1.2	L615D	Pathogenic	0.547
LRP5	O75197-1.2	L615E	Neutral	0.315
LRP5	O75197-1.2	L615F	Neutral	0.109
LRP5	O75197-1.2	L615G	Pathogenic	0.691
LRP5	O75197-1.2	L615H	Neutral	0.481
LRP5	O75197-1.2	L615I	Neutral	0.013
LRP5	O75197-1.2	L615K	Neutral	0.1
LRP5	O75197-1.2	L615M	Neutral	0.01
LRP5	O75197-1.2	L615N	Neutral	0.317
LRP5	O75197-1.2	L615P	Pathogenic	0.6
LRP5	O75197-1.2	L615Q	Neutral	0.181
LRP5	O75197-1.2	L615R	Neutral	0.097
LRP5	O75197-1.2	L615S	Neutral	0.196
LRP5	O75197-1.2	L615T	Neutral	0.097
LRP5	O75197-1.2	L615V	Neutral	0.027
LRP5	O75197-1.2	L615W	Neutral	0.418
LRP5	O75197-1.2	L615Y	Neutral	0.171
LRP5	O75197-1.2	C616A	Pathogenic	0.993
LRP5	O75197-1.2	C616D	Pathogenic	0.999
LRP5	O75197-1.2	C616E	Pathogenic	1.0
LRP5	O75197-1.2	C616F	Pathogenic	0.999
LRP5	O75197-1.2	C616G	Pathogenic	1.0
LRP5	O75197-1.2	C616H	Pathogenic	1.0
LRP5	O75197-1.2	C616I	Pathogenic	0.997
LRP5	O75197-1.2	C616K	Pathogenic	0.999
LRP5	O75197-1.2	C616L	Pathogenic	0.997
LRP5	O75197-1.2	C616M	Pathogenic	0.998
LRP5	O75197-1.2	C616N	Pathogenic	0.999
LRP5	O75197-1.2	C616P	Pathogenic	1.0
LRP5	O75197-1.2	C616Q	Pathogenic	1.0
LRP5	O75197-1.2	C616R	Pathogenic	0.999
LRP5	O75197-1.2	C616S	Pathogenic	0.997
LRP5	O75197-1.2	C616T	Pathogenic	0.998
LRP5	O75197-1.2	C616V	Pathogenic	0.998
LRP5	O75197-1.2	C616W	Pathogenic	0.999
LRP5	O75197-1.2	C616Y	Pathogenic	1.0
LRP5	O75197-1.2	F617A	Neutral	0.022
LRP5	O75197-1.2	F617C	Neutral	0.041
LRP5	O75197-1.2	F617D	Neutral	0.027
LRP5	O75197-1.2	F617E	Neutral	0.031
LRP5	O75197-1.2	F617G	Neutral	0.049
LRP5	O75197-1.2	F617H	Neutral	0.007
LRP5	O75197-1.2	F617I	Neutral	0.01
LRP5	O75197-1.2	F617K	Neutral	0.024
LRP5	O75197-1.2	F617L	Neutral	0.009
LRP5	O75197-1.2	F617M	Neutral	0.006
LRP5	O75197-1.2	F617N	Neutral	0.031
LRP5	O75197-1.2	F617P	Neutral	0.241
LRP5	O75197-1.2	F617Q	Neutral	0.045
LRP5	O75197-1.2	F617R	Neutral	0.023
LRP5	O75197-1.2	F617S	Neutral	0.017
LRP5	O75197-1.2	F617T	Neutral	0.022
LRP5	O75197-1.2	F617V	Neutral	0.018
LRP5	O75197-1.2	F617W	Neutral	0.002
LRP5	O75197-1.2	F617Y	Neutral	0.0
LRP5	O75197-1.2	F618A	Neutral	0.001
LRP5	O75197-1.2	F618C	Neutral	0.002
LRP5	O75197-1.2	F618D	Neutral	0.001
LRP5	O75197-1.2	F618E	Neutral	0.001
LRP5	O75197-1.2	F618G	Neutral	0.002
LRP5	O75197-1.2	F618H	Neutral	0.0
LRP5	O75197-1.2	F618I	Neutral	0.0
LRP5	O75197-1.2	F618K	Neutral	0.001
LRP5	O75197-1.2	F618L	Neutral	0.0
LRP5	O75197-1.2	F618M	Neutral	0.0
LRP5	O75197-1.2	F618N	Neutral	0.001
LRP5	O75197-1.2	F618P	Neutral	0.012
LRP5	O75197-1.2	F618Q	Neutral	0.002
LRP5	O75197-1.2	F618R	Neutral	0.001
LRP5	O75197-1.2	F618S	Neutral	0.001
LRP5	O75197-1.2	F618T	Neutral	0.001
LRP5	O75197-1.2	F618V	Neutral	0.001
LRP5	O75197-1.2	F618W	Neutral	0.0
LRP5	O75197-1.2	F618Y	Neutral	0.0
LRP5	O75197-1.2	T619A	Neutral	0.001
LRP5	O75197-1.2	T619C	Neutral	0.001
LRP5	O75197-1.2	T619D	Neutral	0.001
LRP5	O75197-1.2	T619E	Neutral	0.001
LRP5	O75197-1.2	T619F	Neutral	0.002
LRP5	O75197-1.2	T619G	Neutral	0.005
LRP5	O75197-1.2	T619H	Neutral	0.006
LRP5	O75197-1.2	T619I	Neutral	0.001
LRP5	O75197-1.2	T619K	Neutral	0.001
LRP5	O75197-1.2	T619L	Neutral	0.001
LRP5	O75197-1.2	T619M	Neutral	0.001
LRP5	O75197-1.2	T619N	Neutral	0.0
LRP5	O75197-1.2	T619P	Neutral	0.002
LRP5	O75197-1.2	T619Q	Neutral	0.001
LRP5	O75197-1.2	T619R	Neutral	0.001
LRP5	O75197-1.2	T619S	Neutral	0.0
LRP5	O75197-1.2	T619V	Neutral	0.0
LRP5	O75197-1.2	T619W	Neutral	0.001
LRP5	O75197-1.2	T619Y	Neutral	0.004
LRP5	O75197-1.2	P620A	Neutral	0.125
LRP5	O75197-1.2	P620C	Pathogenic	0.609
LRP5	O75197-1.2	P620D	Neutral	0.054
LRP5	O75197-1.2	P620E	Neutral	0.058
LRP5	O75197-1.2	P620F	Pathogenic	0.683
LRP5	O75197-1.2	P620G	Neutral	0.243
LRP5	O75197-1.2	P620H	Neutral	0.27
LRP5	O75197-1.2	P620I	Neutral	0.416
LRP5	O75197-1.2	P620K	Neutral	0.042
LRP5	O75197-1.2	P620L	Neutral	0.438
LRP5	O75197-1.2	P620M	Neutral	0.281
LRP5	O75197-1.2	P620N	Neutral	0.166
LRP5	O75197-1.2	P620Q	Neutral	0.082
LRP5	O75197-1.2	P620R	Neutral	0.113
LRP5	O75197-1.2	P620S	Neutral	0.096
LRP5	O75197-1.2	P620T	Neutral	0.124
LRP5	O75197-1.2	P620V	Neutral	0.29
LRP5	O75197-1.2	P620W	Pathogenic	0.577
LRP5	O75197-1.2	P620Y	Pathogenic	0.596
LRP5	O75197-1.2	H621A	Neutral	0.0
LRP5	O75197-1.2	H621C	Neutral	0.001
LRP5	O75197-1.2	H621D	Neutral	0.0
LRP5	O75197-1.2	H621E	Neutral	0.0
LRP5	O75197-1.2	H621F	Neutral	0.0
LRP5	O75197-1.2	H621G	Neutral	0.0
LRP5	O75197-1.2	H621I	Neutral	0.0
LRP5	O75197-1.2	H621K	Neutral	0.0
LRP5	O75197-1.2	H621L	Neutral	0.0
LRP5	O75197-1.2	H621M	Neutral	0.0
LRP5	O75197-1.2	H621N	Neutral	0.0
LRP5	O75197-1.2	H621P	Neutral	0.0
LRP5	O75197-1.2	H621Q	Neutral	0.0
LRP5	O75197-1.2	H621R	Neutral	0.0
LRP5	O75197-1.2	H621S	Neutral	0.0
LRP5	O75197-1.2	H621T	Neutral	0.0
LRP5	O75197-1.2	H621V	Neutral	0.0
LRP5	O75197-1.2	H621W	Neutral	0.0
LRP5	O75197-1.2	H621Y	Neutral	0.0
LRP5	O75197-1.2	A622C	Neutral	0.0
LRP5	O75197-1.2	A622D	Neutral	0.0
LRP5	O75197-1.2	A622E	Neutral	0.0
LRP5	O75197-1.2	A622F	Neutral	0.0
LRP5	O75197-1.2	A622G	Neutral	0.0
LRP5	O75197-1.2	A622H	Neutral	0.001
LRP5	O75197-1.2	A622I	Neutral	0.0
LRP5	O75197-1.2	A622K	Neutral	0.0
LRP5	O75197-1.2	A622L	Neutral	0.0
LRP5	O75197-1.2	A622M	Neutral	0.0
LRP5	O75197-1.2	A622N	Neutral	0.0
LRP5	O75197-1.2	A622P	Neutral	0.0
LRP5	O75197-1.2	A622Q	Neutral	0.0
LRP5	O75197-1.2	A622R	Neutral	0.0
LRP5	O75197-1.2	A622S	Neutral	0.0
LRP5	O75197-1.2	A622T	Neutral	0.0
LRP5	O75197-1.2	A622V	Neutral	0.0
LRP5	O75197-1.2	A622W	Neutral	0.0
LRP5	O75197-1.2	A622Y	Neutral	0.0
LRP5	O75197-1.2	T623A	Neutral	0.0
LRP5	O75197-1.2	T623C	Neutral	0.0
LRP5	O75197-1.2	T623D	Neutral	0.0
LRP5	O75197-1.2	T623E	Neutral	0.0
LRP5	O75197-1.2	T623F	Neutral	0.0
LRP5	O75197-1.2	T623G	Neutral	0.0
LRP5	O75197-1.2	T623H	Neutral	0.0
LRP5	O75197-1.2	T623I	Neutral	0.0
LRP5	O75197-1.2	T623K	Neutral	0.0
LRP5	O75197-1.2	T623L	Neutral	0.0
LRP5	O75197-1.2	T623M	Neutral	0.0
LRP5	O75197-1.2	T623N	Neutral	0.0
LRP5	O75197-1.2	T623P	Neutral	0.0
LRP5	O75197-1.2	T623Q	Neutral	0.0
LRP5	O75197-1.2	T623R	Neutral	0.0
LRP5	O75197-1.2	T623S	Neutral	0.0
LRP5	O75197-1.2	T623V	Neutral	0.0
LRP5	O75197-1.2	T623W	Neutral	0.0
LRP5	O75197-1.2	T623Y	Neutral	0.0
LRP5	O75197-1.2	R624A	Neutral	0.0
LRP5	O75197-1.2	R624C	Neutral	0.001
LRP5	O75197-1.2	R624D	Neutral	0.002
LRP5	O75197-1.2	R624E	Neutral	0.0
LRP5	O75197-1.2	R624F	Neutral	0.001
LRP5	O75197-1.2	R624G	Neutral	0.001
LRP5	O75197-1.2	R624H	Neutral	0.0
LRP5	O75197-1.2	R624I	Neutral	0.001
LRP5	O75197-1.2	R624K	Neutral	0.0
LRP5	O75197-1.2	R624L	Neutral	0.0
LRP5	O75197-1.2	R624M	Neutral	0.0
LRP5	O75197-1.2	R624N	Neutral	0.0
LRP5	O75197-1.2	R624P	Neutral	0.0
LRP5	O75197-1.2	R624Q	Neutral	0.0
LRP5	O75197-1.2	R624S	Neutral	0.0
LRP5	O75197-1.2	R624T	Neutral	0.0
LRP5	O75197-1.2	R624V	Neutral	0.001
LRP5	O75197-1.2	R624W	Neutral	0.0
LRP5	O75197-1.2	R624Y	Neutral	0.0
LRP5	O75197-1.2	C625A	Pathogenic	0.993
LRP5	O75197-1.2	C625D	Pathogenic	0.999
LRP5	O75197-1.2	C625E	Pathogenic	1.0
LRP5	O75197-1.2	C625F	Pathogenic	0.999
LRP5	O75197-1.2	C625G	Pathogenic	1.0
LRP5	O75197-1.2	C625H	Pathogenic	1.0
LRP5	O75197-1.2	C625I	Pathogenic	0.997
LRP5	O75197-1.2	C625K	Pathogenic	0.999
LRP5	O75197-1.2	C625L	Pathogenic	0.997
LRP5	O75197-1.2	C625M	Pathogenic	0.998
LRP5	O75197-1.2	C625N	Pathogenic	0.999
LRP5	O75197-1.2	C625P	Pathogenic	1.0
LRP5	O75197-1.2	C625Q	Pathogenic	1.0
LRP5	O75197-1.2	C625R	Pathogenic	0.999
LRP5	O75197-1.2	C625S	Pathogenic	0.997
LRP5	O75197-1.2	C625T	Pathogenic	0.998
LRP5	O75197-1.2	C625V	Pathogenic	0.998
LRP5	O75197-1.2	C625W	Pathogenic	0.999
LRP5	O75197-1.2	C625Y	Pathogenic	1.0
LRP5	O75197-1.2	G626A	Neutral	0.0
LRP5	O75197-1.2	G626C	Neutral	0.007
LRP5	O75197-1.2	G626D	Neutral	0.001
LRP5	O75197-1.2	G626E	Neutral	0.003
LRP5	O75197-1.2	G626F	Neutral	0.003
LRP5	O75197-1.2	G626H	Neutral	0.005
LRP5	O75197-1.2	G626I	Neutral	0.009
LRP5	O75197-1.2	G626K	Neutral	0.002
LRP5	O75197-1.2	G626L	Neutral	0.01
LRP5	O75197-1.2	G626M	Neutral	0.005
LRP5	O75197-1.2	G626N	Neutral	0.0
LRP5	O75197-1.2	G626P	Neutral	0.003
LRP5	O75197-1.2	G626Q	Neutral	0.004
LRP5	O75197-1.2	G626R	Neutral	0.002
LRP5	O75197-1.2	G626S	Neutral	0.001
LRP5	O75197-1.2	G626T	Neutral	0.004
LRP5	O75197-1.2	G626V	Neutral	0.005
LRP5	O75197-1.2	G626W	Neutral	0.001
LRP5	O75197-1.2	G626Y	Neutral	0.006
LRP5	O75197-1.2	C627A	Pathogenic	0.994
LRP5	O75197-1.2	C627D	Pathogenic	0.999
LRP5	O75197-1.2	C627E	Pathogenic	1.0
LRP5	O75197-1.2	C627F	Pathogenic	0.999
LRP5	O75197-1.2	C627G	Pathogenic	1.0
LRP5	O75197-1.2	C627H	Pathogenic	1.0
LRP5	O75197-1.2	C627I	Pathogenic	0.998
LRP5	O75197-1.2	C627K	Pathogenic	0.999
LRP5	O75197-1.2	C627L	Pathogenic	0.998
LRP5	O75197-1.2	C627M	Pathogenic	0.999
LRP5	O75197-1.2	C627N	Pathogenic	1.0
LRP5	O75197-1.2	C627P	Pathogenic	1.0
LRP5	O75197-1.2	C627Q	Pathogenic	1.0
LRP5	O75197-1.2	C627R	Pathogenic	0.999
LRP5	O75197-1.2	C627S	Pathogenic	0.997
LRP5	O75197-1.2	C627T	Pathogenic	0.998
LRP5	O75197-1.2	C627V	Pathogenic	0.999
LRP5	O75197-1.2	C627W	Pathogenic	0.999
LRP5	O75197-1.2	C627Y	Pathogenic	1.0
LRP5	O75197-1.2	P628A	Neutral	0.085
LRP5	O75197-1.2	P628C	Pathogenic	0.503
LRP5	O75197-1.2	P628D	Neutral	0.035
LRP5	O75197-1.2	P628E	Neutral	0.039
LRP5	O75197-1.2	P628F	Pathogenic	0.584
LRP5	O75197-1.2	P628G	Neutral	0.173
LRP5	O75197-1.2	P628H	Neutral	0.194
LRP5	O75197-1.2	P628I	Neutral	0.317
LRP5	O75197-1.2	P628K	Neutral	0.027
LRP5	O75197-1.2	P628L	Neutral	0.337
LRP5	O75197-1.2	P628M	Neutral	0.203
LRP5	O75197-1.2	P628N	Neutral	0.114
LRP5	O75197-1.2	P628Q	Neutral	0.055
LRP5	O75197-1.2	P628R	Neutral	0.077
LRP5	O75197-1.2	P628S	Neutral	0.065
LRP5	O75197-1.2	P628T	Neutral	0.084
LRP5	O75197-1.2	P628V	Neutral	0.21
LRP5	O75197-1.2	P628W	Neutral	0.47
LRP5	O75197-1.2	P628Y	Neutral	0.489
LRP5	O75197-1.2	I629A	Neutral	0.005
LRP5	O75197-1.2	I629C	Neutral	0.009
LRP5	O75197-1.2	I629D	Neutral	0.017
LRP5	O75197-1.2	I629E	Neutral	0.019
LRP5	O75197-1.2	I629F	Neutral	0.006
LRP5	O75197-1.2	I629G	Neutral	0.088
LRP5	O75197-1.2	I629H	Neutral	0.039
LRP5	O75197-1.2	I629K	Neutral	0.014
LRP5	O75197-1.2	I629L	Neutral	0.001
LRP5	O75197-1.2	I629M	Neutral	0.001
LRP5	O75197-1.2	I629N	Neutral	0.02
LRP5	O75197-1.2	I629P	Neutral	0.061
LRP5	O75197-1.2	I629Q	Neutral	0.028
LRP5	O75197-1.2	I629R	Neutral	0.014
LRP5	O75197-1.2	I629S	Neutral	0.01
LRP5	O75197-1.2	I629T	Neutral	0.005
LRP5	O75197-1.2	I629V	Neutral	0.0
LRP5	O75197-1.2	I629W	Neutral	0.102
LRP5	O75197-1.2	I629Y	Neutral	0.009
LRP5	O75197-1.2	G630A	Neutral	0.086
LRP5	O75197-1.2	G630C	Pathogenic	0.585
LRP5	O75197-1.2	G630D	Neutral	0.155
LRP5	O75197-1.2	G630E	Neutral	0.378
LRP5	O75197-1.2	G630F	Neutral	0.388
LRP5	O75197-1.2	G630H	Neutral	0.485
LRP5	O75197-1.2	G630I	Pathogenic	0.66
LRP5	O75197-1.2	G630K	Neutral	0.299
LRP5	O75197-1.2	G630L	Pathogenic	0.68
LRP5	O75197-1.2	G630M	Pathogenic	0.515
LRP5	O75197-1.2	G630N	Neutral	0.065
LRP5	O75197-1.2	G630P	Neutral	0.369
LRP5	O75197-1.2	G630Q	Neutral	0.467
LRP5	O75197-1.2	G630R	Neutral	0.292
LRP5	O75197-1.2	G630S	Neutral	0.107
LRP5	O75197-1.2	G630T	Neutral	0.468
LRP5	O75197-1.2	G630V	Pathogenic	0.526
LRP5	O75197-1.2	G630W	Neutral	0.117
LRP5	O75197-1.2	G630Y	Pathogenic	0.569
LRP5	O75197-1.2	L631A	Neutral	0.001
LRP5	O75197-1.2	L631C	Neutral	0.002
LRP5	O75197-1.2	L631D	Neutral	0.012
LRP5	O75197-1.2	L631E	Neutral	0.005
LRP5	O75197-1.2	L631F	Neutral	0.001
LRP5	O75197-1.2	L631G	Neutral	0.022
LRP5	O75197-1.2	L631H	Neutral	0.009
LRP5	O75197-1.2	L631I	Neutral	0.0
LRP5	O75197-1.2	L631K	Neutral	0.001
LRP5	O75197-1.2	L631M	Neutral	0.0
LRP5	O75197-1.2	L631N	Neutral	0.005
LRP5	O75197-1.2	L631P	Neutral	0.015
LRP5	O75197-1.2	L631Q	Neutral	0.002
LRP5	O75197-1.2	L631R	Neutral	0.001
LRP5	O75197-1.2	L631S	Neutral	0.002
LRP5	O75197-1.2	L631T	Neutral	0.001
LRP5	O75197-1.2	L631V	Neutral	0.0
LRP5	O75197-1.2	L631W	Neutral	0.007
LRP5	O75197-1.2	L631Y	Neutral	0.002
LRP5	O75197-1.2	E632A	Neutral	0.188
LRP5	O75197-1.2	E632C	Pathogenic	0.786
LRP5	O75197-1.2	E632D	Neutral	0.017
LRP5	O75197-1.2	E632F	Neutral	0.369
LRP5	O75197-1.2	E632G	Neutral	0.473
LRP5	O75197-1.2	E632H	Neutral	0.086
LRP5	O75197-1.2	E632I	Neutral	0.37
LRP5	O75197-1.2	E632K	Neutral	0.042
LRP5	O75197-1.2	E632L	Neutral	0.391
LRP5	O75197-1.2	E632M	Neutral	0.243
LRP5	O75197-1.2	E632N	Neutral	0.152
LRP5	O75197-1.2	E632P	Neutral	0.142
LRP5	O75197-1.2	E632Q	Neutral	0.014
LRP5	O75197-1.2	E632R	Neutral	0.114
LRP5	O75197-1.2	E632S	Neutral	0.095
LRP5	O75197-1.2	E632T	Neutral	0.201
LRP5	O75197-1.2	E632V	Neutral	0.249
LRP5	O75197-1.2	E632W	Neutral	0.27
LRP5	O75197-1.2	E632Y	Neutral	0.285
LRP5	O75197-1.2	L633A	Neutral	0.097
LRP5	O75197-1.2	L633C	Neutral	0.169
LRP5	O75197-1.2	L633D	Pathogenic	0.547
LRP5	O75197-1.2	L633E	Neutral	0.315
LRP5	O75197-1.2	L633F	Neutral	0.109
LRP5	O75197-1.2	L633G	Pathogenic	0.691
LRP5	O75197-1.2	L633H	Neutral	0.481
LRP5	O75197-1.2	L633I	Neutral	0.013
LRP5	O75197-1.2	L633K	Neutral	0.1
LRP5	O75197-1.2	L633M	Neutral	0.01
LRP5	O75197-1.2	L633N	Neutral	0.317
LRP5	O75197-1.2	L633P	Pathogenic	0.6
LRP5	O75197-1.2	L633Q	Neutral	0.181
LRP5	O75197-1.2	L633R	Neutral	0.097
LRP5	O75197-1.2	L633S	Neutral	0.196
LRP5	O75197-1.2	L633T	Neutral	0.097
LRP5	O75197-1.2	L633V	Neutral	0.027
LRP5	O75197-1.2	L633W	Neutral	0.418
LRP5	O75197-1.2	L633Y	Neutral	0.171
LRP5	O75197-1.2	L634A	Neutral	0.0
LRP5	O75197-1.2	L634C	Neutral	0.001
LRP5	O75197-1.2	L634D	Neutral	0.004
LRP5	O75197-1.2	L634E	Neutral	0.001
LRP5	O75197-1.2	L634F	Neutral	0.0
LRP5	O75197-1.2	L634G	Neutral	0.007
LRP5	O75197-1.2	L634H	Neutral	0.003
LRP5	O75197-1.2	L634I	Neutral	0.0
LRP5	O75197-1.2	L634K	Neutral	0.0
LRP5	O75197-1.2	L634M	Neutral	0.0
LRP5	O75197-1.2	L634N	Neutral	0.001
LRP5	O75197-1.2	L634P	Neutral	0.005
LRP5	O75197-1.2	L634Q	Neutral	0.001
LRP5	O75197-1.2	L634R	Neutral	0.0
LRP5	O75197-1.2	L634S	Neutral	0.001
LRP5	O75197-1.2	L634T	Neutral	0.0
LRP5	O75197-1.2	L634V	Neutral	0.0
LRP5	O75197-1.2	L634W	Neutral	0.002
LRP5	O75197-1.2	L634Y	Neutral	0.001
LRP5	O75197-1.2	S635A	Neutral	0.0
LRP5	O75197-1.2	S635C	Neutral	0.001
LRP5	O75197-1.2	S635D	Neutral	0.0
LRP5	O75197-1.2	S635E	Neutral	0.0
LRP5	O75197-1.2	S635F	Neutral	0.001
LRP5	O75197-1.2	S635G	Neutral	0.001
LRP5	O75197-1.2	S635H	Neutral	0.002
LRP5	O75197-1.2	S635I	Neutral	0.001
LRP5	O75197-1.2	S635K	Neutral	0.0
LRP5	O75197-1.2	S635L	Neutral	0.001
LRP5	O75197-1.2	S635M	Neutral	0.001
LRP5	O75197-1.2	S635N	Neutral	0.0
LRP5	O75197-1.2	S635P	Neutral	0.001
LRP5	O75197-1.2	S635Q	Neutral	0.001
LRP5	O75197-1.2	S635R	Neutral	0.001
LRP5	O75197-1.2	S635T	Neutral	0.0
LRP5	O75197-1.2	S635V	Neutral	0.002
LRP5	O75197-1.2	S635W	Neutral	0.002
LRP5	O75197-1.2	S635Y	Neutral	0.002
LRP5	O75197-1.2	D636A	Neutral	0.197
LRP5	O75197-1.2	D636C	Neutral	0.296
LRP5	O75197-1.2	D636E	Neutral	0.007
LRP5	O75197-1.2	D636F	Neutral	0.161
LRP5	O75197-1.2	D636G	Neutral	0.093
LRP5	O75197-1.2	D636H	Neutral	0.086
LRP5	O75197-1.2	D636I	Neutral	0.162
LRP5	O75197-1.2	D636K	Neutral	0.144
LRP5	O75197-1.2	D636L	Neutral	0.392
LRP5	O75197-1.2	D636M	Neutral	0.244
LRP5	O75197-1.2	D636N	Neutral	0.02
LRP5	O75197-1.2	D636P	Neutral	0.055
LRP5	O75197-1.2	D636Q	Neutral	0.041
LRP5	O75197-1.2	D636R	Neutral	0.331
LRP5	O75197-1.2	D636S	Neutral	0.035
LRP5	O75197-1.2	D636T	Neutral	0.08
LRP5	O75197-1.2	D636V	Neutral	0.252
LRP5	O75197-1.2	D636W	Neutral	0.27
LRP5	O75197-1.2	D636Y	Neutral	0.285
LRP5	O75197-1.2	M637A	Neutral	0.005
LRP5	O75197-1.2	M637C	Neutral	0.009
LRP5	O75197-1.2	M637D	Neutral	0.017
LRP5	O75197-1.2	M637E	Neutral	0.007
LRP5	O75197-1.2	M637F	Neutral	0.002
LRP5	O75197-1.2	M637G	Neutral	0.031
LRP5	O75197-1.2	M637H	Neutral	0.013
LRP5	O75197-1.2	M637I	Neutral	0.001
LRP5	O75197-1.2	M637K	Neutral	0.002
LRP5	O75197-1.2	M637L	Neutral	0.0
LRP5	O75197-1.2	M637N	Neutral	0.007
LRP5	O75197-1.2	M637P	Neutral	0.021
LRP5	O75197-1.2	M637Q	Neutral	0.001
LRP5	O75197-1.2	M637R	Neutral	0.002
LRP5	O75197-1.2	M637S	Neutral	0.003
LRP5	O75197-1.2	M637T	Neutral	0.005
LRP5	O75197-1.2	M637V	Neutral	0.001
LRP5	O75197-1.2	M637W	Neutral	0.004
LRP5	O75197-1.2	M637Y	Neutral	0.009
LRP5	O75197-1.2	K638A	Neutral	0.003
LRP5	O75197-1.2	K638C	Neutral	0.015
LRP5	O75197-1.2	K638D	Neutral	0.008
LRP5	O75197-1.2	K638E	Neutral	0.001
LRP5	O75197-1.2	K638F	Neutral	0.008
LRP5	O75197-1.2	K638G	Neutral	0.011
LRP5	O75197-1.2	K638H	Neutral	0.004
LRP5	O75197-1.2	K638I	Neutral	0.008
LRP5	O75197-1.2	K638L	Neutral	0.003
LRP5	O75197-1.2	K638M	Neutral	0.001
LRP5	O75197-1.2	K638N	Neutral	0.002
LRP5	O75197-1.2	K638P	Neutral	0.002
LRP5	O75197-1.2	K638Q	Neutral	0.001
LRP5	O75197-1.2	K638R	Neutral	0.0
LRP5	O75197-1.2	K638S	Neutral	0.001
LRP5	O75197-1.2	K638T	Neutral	0.003
LRP5	O75197-1.2	K638V	Neutral	0.004
LRP5	O75197-1.2	K638W	Neutral	0.005
LRP5	O75197-1.2	K638Y	Neutral	0.005
LRP5	O75197-1.2	T639A	Neutral	0.067
LRP5	O75197-1.2	T639C	Neutral	0.11
LRP5	O75197-1.2	T639D	Neutral	0.087
LRP5	O75197-1.2	T639E	Neutral	0.095
LRP5	O75197-1.2	T639F	Neutral	0.148
LRP5	O75197-1.2	T639G	Neutral	0.35
LRP5	O75197-1.2	T639H	Neutral	0.385
LRP5	O75197-1.2	T639I	Neutral	0.054
LRP5	O75197-1.2	T639K	Neutral	0.068
LRP5	O75197-1.2	T639L	Neutral	0.059
LRP5	O75197-1.2	T639M	Neutral	0.087
LRP5	O75197-1.2	T639N	Neutral	0.035
LRP5	O75197-1.2	T639P	Neutral	0.136
LRP5	O75197-1.2	T639Q	Neutral	0.131
LRP5	O75197-1.2	T639R	Neutral	0.066
LRP5	O75197-1.2	T639S	Neutral	0.019
LRP5	O75197-1.2	T639V	Neutral	0.032
LRP5	O75197-1.2	T639W	Neutral	0.099
LRP5	O75197-1.2	T639Y	Neutral	0.265
LRP5	O75197-1.2	C640A	Pathogenic	0.993
LRP5	O75197-1.2	C640D	Pathogenic	0.999
LRP5	O75197-1.2	C640E	Pathogenic	1.0
LRP5	O75197-1.2	C640F	Pathogenic	0.999
LRP5	O75197-1.2	C640G	Pathogenic	1.0
LRP5	O75197-1.2	C640H	Pathogenic	1.0
LRP5	O75197-1.2	C640I	Pathogenic	0.997
LRP5	O75197-1.2	C640K	Pathogenic	0.999
LRP5	O75197-1.2	C640L	Pathogenic	0.997
LRP5	O75197-1.2	C640M	Pathogenic	0.998
LRP5	O75197-1.2	C640N	Pathogenic	0.999
LRP5	O75197-1.2	C640P	Pathogenic	1.0
LRP5	O75197-1.2	C640Q	Pathogenic	1.0
LRP5	O75197-1.2	C640R	Pathogenic	0.999
LRP5	O75197-1.2	C640S	Pathogenic	0.997
LRP5	O75197-1.2	C640T	Pathogenic	0.998
LRP5	O75197-1.2	C640V	Pathogenic	0.998
LRP5	O75197-1.2	C640W	Pathogenic	0.999
LRP5	O75197-1.2	C640Y	Pathogenic	1.0
LRP5	O75197-1.2	I641A	Neutral	0.009
LRP5	O75197-1.2	I641C	Neutral	0.016
LRP5	O75197-1.2	I641D	Neutral	0.031
LRP5	O75197-1.2	I641E	Neutral	0.036
LRP5	O75197-1.2	I641F	Neutral	0.012
LRP5	O75197-1.2	I641G	Neutral	0.155
LRP5	O75197-1.2	I641H	Neutral	0.071
LRP5	O75197-1.2	I641K	Neutral	0.027
LRP5	O75197-1.2	I641L	Neutral	0.001
LRP5	O75197-1.2	I641M	Neutral	0.002
LRP5	O75197-1.2	I641N	Neutral	0.037
LRP5	O75197-1.2	I641P	Neutral	0.109
LRP5	O75197-1.2	I641Q	Neutral	0.052
LRP5	O75197-1.2	I641R	Neutral	0.026
LRP5	O75197-1.2	I641S	Neutral	0.02
LRP5	O75197-1.2	I641T	Neutral	0.009
LRP5	O75197-1.2	I641V	Neutral	0.0
LRP5	O75197-1.2	I641W	Neutral	0.177
LRP5	O75197-1.2	I641Y	Neutral	0.017
LRP5	O75197-1.2	V642A	Neutral	0.008
LRP5	O75197-1.2	V642C	Neutral	0.044
LRP5	O75197-1.2	V642D	Neutral	0.082
LRP5	O75197-1.2	V642E	Neutral	0.032
LRP5	O75197-1.2	V642F	Neutral	0.032
LRP5	O75197-1.2	V642G	Neutral	0.142
LRP5	O75197-1.2	V642H	Neutral	0.166
LRP5	O75197-1.2	V642I	Neutral	0.0
LRP5	O75197-1.2	V642K	Neutral	0.023
LRP5	O75197-1.2	V642L	Neutral	0.004
LRP5	O75197-1.2	V642M	Neutral	0.006
LRP5	O75197-1.2	V642N	Neutral	0.094
LRP5	O75197-1.2	V642P	Neutral	0.099
LRP5	O75197-1.2	V642Q	Neutral	0.046
LRP5	O75197-1.2	V642R	Neutral	0.064
LRP5	O75197-1.2	V642S	Neutral	0.052
LRP5	O75197-1.2	V642T	Neutral	0.008
LRP5	O75197-1.2	V642W	Neutral	0.163
LRP5	O75197-1.2	V642Y	Neutral	0.042
LRP5	O75197-1.2	P643A	Neutral	0.233
LRP5	O75197-1.2	P643C	Pathogenic	0.768
LRP5	O75197-1.2	P643D	Neutral	0.107
LRP5	O75197-1.2	P643E	Neutral	0.116
LRP5	O75197-1.2	P643F	Pathogenic	0.821
LRP5	O75197-1.2	P643G	Neutral	0.405
LRP5	O75197-1.2	P643H	Neutral	0.44
LRP5	O75197-1.2	P643I	Pathogenic	0.602
LRP5	O75197-1.2	P643K	Neutral	0.084
LRP5	O75197-1.2	P643L	Pathogenic	0.624
LRP5	O75197-1.2	P643M	Neutral	0.453
LRP5	O75197-1.2	P643N	Neutral	0.297
LRP5	O75197-1.2	P643Q	Neutral	0.159
LRP5	O75197-1.2	P643R	Neutral	0.213
LRP5	O75197-1.2	P643S	Neutral	0.184
LRP5	O75197-1.2	P643T	Neutral	0.231
LRP5	O75197-1.2	P643V	Neutral	0.464
LRP5	O75197-1.2	P643W	Pathogenic	0.744
LRP5	O75197-1.2	P643Y	Pathogenic	0.758
LRP5	O75197-1.2	E644A	Pathogenic	0.967
LRP5	O75197-1.2	E644C	Pathogenic	0.998
LRP5	O75197-1.2	E644D	Pathogenic	0.691
LRP5	O75197-1.2	E644F	Pathogenic	0.987
LRP5	O75197-1.2	E644G	Pathogenic	0.991
LRP5	O75197-1.2	E644H	Pathogenic	0.922
LRP5	O75197-1.2	E644I	Pathogenic	0.987
LRP5	O75197-1.2	E644K	Pathogenic	0.846
LRP5	O75197-1.2	E644L	Pathogenic	0.988
LRP5	O75197-1.2	E644M	Pathogenic	0.976
LRP5	O75197-1.2	E644N	Pathogenic	0.958
LRP5	O75197-1.2	E644P	Pathogenic	0.955
LRP5	O75197-1.2	E644Q	Pathogenic	0.638
LRP5	O75197-1.2	E644R	Pathogenic	0.942
LRP5	O75197-1.2	E644S	Pathogenic	0.93
LRP5	O75197-1.2	E644T	Pathogenic	0.97
LRP5	O75197-1.2	E644V	Pathogenic	0.977
LRP5	O75197-1.2	E644W	Pathogenic	0.979
LRP5	O75197-1.2	E644Y	Pathogenic	0.981
LRP5	O75197-1.2	A645C	Pathogenic	0.98
LRP5	O75197-1.2	A645D	Pathogenic	0.997
LRP5	O75197-1.2	A645E	Pathogenic	0.991
LRP5	O75197-1.2	A645F	Pathogenic	0.995
LRP5	O75197-1.2	A645G	Pathogenic	0.985
LRP5	O75197-1.2	A645H	Pathogenic	0.998
LRP5	O75197-1.2	A645I	Pathogenic	0.985
LRP5	O75197-1.2	A645K	Pathogenic	0.987
LRP5	O75197-1.2	A645L	Pathogenic	0.986
LRP5	O75197-1.2	A645M	Pathogenic	0.991
LRP5	O75197-1.2	A645N	Pathogenic	0.997
LRP5	O75197-1.2	A645P	Pathogenic	0.995
LRP5	O75197-1.2	A645Q	Pathogenic	0.994
LRP5	O75197-1.2	A645R	Pathogenic	0.987
LRP5	O75197-1.2	A645S	Pathogenic	0.956
LRP5	O75197-1.2	A645T	Pathogenic	0.988
LRP5	O75197-1.2	A645V	Pathogenic	0.974
LRP5	O75197-1.2	A645W	Pathogenic	0.997
LRP5	O75197-1.2	A645Y	Pathogenic	0.998
LRP5	O75197-1.2	F646A	Pathogenic	0.998
LRP5	O75197-1.2	F646C	Pathogenic	0.999
LRP5	O75197-1.2	F646D	Pathogenic	0.998
LRP5	O75197-1.2	F646E	Pathogenic	0.999
LRP5	O75197-1.2	F646G	Pathogenic	0.999
LRP5	O75197-1.2	F646H	Pathogenic	0.994
LRP5	O75197-1.2	F646I	Pathogenic	0.996
LRP5	O75197-1.2	F646K	Pathogenic	0.998
LRP5	O75197-1.2	F646L	Pathogenic	0.995
LRP5	O75197-1.2	F646M	Pathogenic	0.993
LRP5	O75197-1.2	F646N	Pathogenic	0.999
LRP5	O75197-1.2	F646P	Pathogenic	1.0
LRP5	O75197-1.2	F646Q	Pathogenic	0.999
LRP5	O75197-1.2	F646R	Pathogenic	0.998
LRP5	O75197-1.2	F646S	Pathogenic	0.997
LRP5	O75197-1.2	F646T	Pathogenic	0.998
LRP5	O75197-1.2	F646V	Pathogenic	0.998
LRP5	O75197-1.2	F646W	Pathogenic	0.98
LRP5	O75197-1.2	F646Y	Pathogenic	0.798
LRP5	O75197-1.2	L647A	Pathogenic	0.966
LRP5	O75197-1.2	L647C	Pathogenic	0.981
LRP5	O75197-1.2	L647D	Pathogenic	0.997
LRP5	O75197-1.2	L647E	Pathogenic	0.992
LRP5	O75197-1.2	L647F	Pathogenic	0.97
LRP5	O75197-1.2	L647G	Pathogenic	0.998
LRP5	O75197-1.2	L647H	Pathogenic	0.996
LRP5	O75197-1.2	L647I	Pathogenic	0.776
LRP5	O75197-1.2	L647K	Pathogenic	0.966
LRP5	O75197-1.2	L647M	Pathogenic	0.714
LRP5	O75197-1.2	L647N	Pathogenic	0.992
LRP5	O75197-1.2	L647P	Pathogenic	0.997
LRP5	O75197-1.2	L647Q	Pathogenic	0.983
LRP5	O75197-1.2	L647R	Pathogenic	0.965
LRP5	O75197-1.2	L647S	Pathogenic	0.984
LRP5	O75197-1.2	L647T	Pathogenic	0.965
LRP5	O75197-1.2	L647V	Pathogenic	0.879
LRP5	O75197-1.2	L647W	Pathogenic	0.995
LRP5	O75197-1.2	L647Y	Pathogenic	0.982
LRP5	O75197-1.2	V648A	Neutral	0.438
LRP5	O75197-1.2	V648C	Pathogenic	0.817
LRP5	O75197-1.2	V648D	Pathogenic	0.897
LRP5	O75197-1.2	V648E	Pathogenic	0.766
LRP5	O75197-1.2	V648F	Pathogenic	0.764
LRP5	O75197-1.2	V648G	Pathogenic	0.942
LRP5	O75197-1.2	V648H	Pathogenic	0.951
LRP5	O75197-1.2	V648I	Neutral	0.037
LRP5	O75197-1.2	V648K	Pathogenic	0.696
LRP5	O75197-1.2	V648L	Neutral	0.278
LRP5	O75197-1.2	V648M	Neutral	0.37
LRP5	O75197-1.2	V648N	Pathogenic	0.911
LRP5	O75197-1.2	V648P	Pathogenic	0.915
LRP5	O75197-1.2	V648Q	Pathogenic	0.825
LRP5	O75197-1.2	V648R	Pathogenic	0.871
LRP5	O75197-1.2	V648S	Pathogenic	0.842
LRP5	O75197-1.2	V648T	Neutral	0.437
LRP5	O75197-1.2	V648W	Pathogenic	0.95
LRP5	O75197-1.2	V648Y	Pathogenic	0.81
LRP5	O75197-1.2	F649A	Pathogenic	0.998
LRP5	O75197-1.2	F649C	Pathogenic	0.999
LRP5	O75197-1.2	F649D	Pathogenic	0.998
LRP5	O75197-1.2	F649E	Pathogenic	0.998
LRP5	O75197-1.2	F649G	Pathogenic	0.999
LRP5	O75197-1.2	F649H	Pathogenic	0.992
LRP5	O75197-1.2	F649I	Pathogenic	0.995
LRP5	O75197-1.2	F649K	Pathogenic	0.998
LRP5	O75197-1.2	F649L	Pathogenic	0.994
LRP5	O75197-1.2	F649M	Pathogenic	0.992
LRP5	O75197-1.2	F649N	Pathogenic	0.998
LRP5	O75197-1.2	F649P	Pathogenic	1.0
LRP5	O75197-1.2	F649Q	Pathogenic	0.999
LRP5	O75197-1.2	F649R	Pathogenic	0.998
LRP5	O75197-1.2	F649S	Pathogenic	0.997
LRP5	O75197-1.2	F649T	Pathogenic	0.998
LRP5	O75197-1.2	F649V	Pathogenic	0.997
LRP5	O75197-1.2	F649W	Pathogenic	0.976
LRP5	O75197-1.2	F649Y	Pathogenic	0.767
LRP5	O75197-1.2	T650A	Neutral	0.367
LRP5	O75197-1.2	T650C	Neutral	0.499
LRP5	O75197-1.2	T650D	Neutral	0.434
LRP5	O75197-1.2	T650E	Neutral	0.458
LRP5	O75197-1.2	T650F	Pathogenic	0.582
LRP5	O75197-1.2	T650G	Pathogenic	0.813
LRP5	O75197-1.2	T650H	Pathogenic	0.834
LRP5	O75197-1.2	T650I	Neutral	0.315
LRP5	O75197-1.2	T650K	Neutral	0.371
LRP5	O75197-1.2	T650L	Neutral	0.335
LRP5	O75197-1.2	T650M	Neutral	0.434
LRP5	O75197-1.2	T650N	Neutral	0.226
LRP5	O75197-1.2	T650P	Pathogenic	0.559
LRP5	O75197-1.2	T650Q	Pathogenic	0.549
LRP5	O75197-1.2	T650R	Neutral	0.364
LRP5	O75197-1.2	T650S	Neutral	0.134
LRP5	O75197-1.2	T650V	Neutral	0.208
LRP5	O75197-1.2	T650W	Neutral	0.468
LRP5	O75197-1.2	T650Y	Pathogenic	0.743
LRP5	O75197-1.2	S651A	Neutral	0.037
LRP5	O75197-1.2	S651C	Neutral	0.163
LRP5	O75197-1.2	S651D	Neutral	0.076
LRP5	O75197-1.2	S651E	Neutral	0.082
LRP5	O75197-1.2	S651F	Neutral	0.21
LRP5	O75197-1.2	S651G	Neutral	0.131
LRP5	O75197-1.2	S651H	Neutral	0.283
LRP5	O75197-1.2	S651I	Neutral	0.211
LRP5	O75197-1.2	S651K	Neutral	0.059
LRP5	O75197-1.2	S651L	Neutral	0.227
LRP5	O75197-1.2	S651M	Neutral	0.128
LRP5	O75197-1.2	S651N	Neutral	0.03
LRP5	O75197-1.2	S651P	Neutral	0.197
LRP5	O75197-1.2	S651Q	Neutral	0.114
LRP5	O75197-1.2	S651R	Neutral	0.156
LRP5	O75197-1.2	S651T	Neutral	0.038
LRP5	O75197-1.2	S651V	Neutral	0.318
LRP5	O75197-1.2	S651W	Neutral	0.339
LRP5	O75197-1.2	S651Y	Neutral	0.356
LRP5	O75197-1.2	R652A	Pathogenic	0.793
LRP5	O75197-1.2	R652C	Pathogenic	0.952
LRP5	O75197-1.2	R652D	Pathogenic	0.97
LRP5	O75197-1.2	R652E	Pathogenic	0.759
LRP5	O75197-1.2	R652F	Pathogenic	0.913
LRP5	O75197-1.2	R652G	Pathogenic	0.937
LRP5	O75197-1.2	R652H	Pathogenic	0.616
LRP5	O75197-1.2	R652I	Pathogenic	0.911
LRP5	O75197-1.2	R652K	Neutral	0.327
LRP5	O75197-1.2	R652L	Pathogenic	0.787
LRP5	O75197-1.2	R652M	Pathogenic	0.648
LRP5	O75197-1.2	R652N	Pathogenic	0.749
LRP5	O75197-1.2	R652P	Pathogenic	0.894
LRP5	O75197-1.2	R652Q	Neutral	0.418
LRP5	O75197-1.2	R652S	Pathogenic	0.841
LRP5	O75197-1.2	R652T	Pathogenic	0.807
LRP5	O75197-1.2	R652V	Pathogenic	0.944
LRP5	O75197-1.2	R652W	Pathogenic	0.874
LRP5	O75197-1.2	R652Y	Pathogenic	0.88
LRP5	O75197-1.2	A653C	Neutral	0.415
LRP5	O75197-1.2	A653D	Pathogenic	0.819
LRP5	O75197-1.2	A653E	Pathogenic	0.62
LRP5	O75197-1.2	A653F	Pathogenic	0.747
LRP5	O75197-1.2	A653G	Neutral	0.496
LRP5	O75197-1.2	A653H	Pathogenic	0.907
LRP5	O75197-1.2	A653I	Neutral	0.493
LRP5	O75197-1.2	A653K	Pathogenic	0.533
LRP5	O75197-1.2	A653L	Pathogenic	0.516
LRP5	O75197-1.2	A653M	Pathogenic	0.619
LRP5	O75197-1.2	A653N	Pathogenic	0.84
LRP5	O75197-1.2	A653P	Pathogenic	0.731
LRP5	O75197-1.2	A653Q	Pathogenic	0.701
LRP5	O75197-1.2	A653R	Pathogenic	0.524
LRP5	O75197-1.2	A653S	Neutral	0.242
LRP5	O75197-1.2	A653T	Pathogenic	0.55
LRP5	O75197-1.2	A653V	Neutral	0.358
LRP5	O75197-1.2	A653W	Pathogenic	0.85
LRP5	O75197-1.2	A653Y	Pathogenic	0.86
LRP5	O75197-1.2	A654C	Neutral	0.072
LRP5	O75197-1.2	A654D	Neutral	0.331
LRP5	O75197-1.2	A654E	Neutral	0.151
LRP5	O75197-1.2	A654F	Neutral	0.244
LRP5	O75197-1.2	A654G	Neutral	0.097
LRP5	O75197-1.2	A654H	Pathogenic	0.515
LRP5	O75197-1.2	A654I	Neutral	0.096
LRP5	O75197-1.2	A654K	Neutral	0.111
LRP5	O75197-1.2	A654L	Neutral	0.104
LRP5	O75197-1.2	A654M	Neutral	0.151
LRP5	O75197-1.2	A654N	Neutral	0.364
LRP5	O75197-1.2	A654P	Neutral	0.229
LRP5	O75197-1.2	A654Q	Neutral	0.204
LRP5	O75197-1.2	A654R	Neutral	0.108
LRP5	O75197-1.2	A654S	Neutral	0.034
LRP5	O75197-1.2	A654T	Neutral	0.118
LRP5	O75197-1.2	A654V	Neutral	0.057
LRP5	O75197-1.2	A654W	Neutral	0.383
LRP5	O75197-1.2	A654Y	Neutral	0.401
LRP5	O75197-1.2	I655A	Pathogenic	0.951
LRP5	O75197-1.2	I655C	Pathogenic	0.973
LRP5	O75197-1.2	I655D	Pathogenic	0.986
LRP5	O75197-1.2	I655E	Pathogenic	0.988
LRP5	O75197-1.2	I655F	Pathogenic	0.963
LRP5	O75197-1.2	I655G	Pathogenic	0.998
LRP5	O75197-1.2	I655H	Pathogenic	0.994
LRP5	O75197-1.2	I655K	Pathogenic	0.984
LRP5	O75197-1.2	I655L	Pathogenic	0.725
LRP5	O75197-1.2	I655M	Pathogenic	0.841
LRP5	O75197-1.2	I655N	Pathogenic	0.988
LRP5	O75197-1.2	I655P	Pathogenic	0.996
LRP5	O75197-1.2	I655Q	Pathogenic	0.992
LRP5	O75197-1.2	I655R	Pathogenic	0.983
LRP5	O75197-1.2	I655S	Pathogenic	0.978
LRP5	O75197-1.2	I655T	Pathogenic	0.951
LRP5	O75197-1.2	I655V	Neutral	0.353
LRP5	O75197-1.2	I655W	Pathogenic	0.998
LRP5	O75197-1.2	I655Y	Pathogenic	0.974
LRP5	O75197-1.2	H656A	Pathogenic	0.911
LRP5	O75197-1.2	H656C	Pathogenic	0.946
LRP5	O75197-1.2	H656D	Pathogenic	0.646
LRP5	O75197-1.2	H656E	Neutral	0.409
LRP5	O75197-1.2	H656F	Neutral	0.485
LRP5	O75197-1.2	H656G	Pathogenic	0.911
LRP5	O75197-1.2	H656I	Pathogenic	0.898
LRP5	O75197-1.2	H656K	Pathogenic	0.603
LRP5	O75197-1.2	H656L	Pathogenic	0.906
LRP5	O75197-1.2	H656M	Pathogenic	0.828
LRP5	O75197-1.2	H656N	Neutral	0.187
LRP5	O75197-1.2	H656P	Pathogenic	0.88
LRP5	O75197-1.2	H656Q	Pathogenic	0.504
LRP5	O75197-1.2	H656R	Neutral	0.326
LRP5	O75197-1.2	H656S	Pathogenic	0.773
LRP5	O75197-1.2	H656T	Pathogenic	0.918
LRP5	O75197-1.2	H656V	Pathogenic	0.936
LRP5	O75197-1.2	H656W	Pathogenic	0.644
LRP5	O75197-1.2	H656Y	Neutral	0.065
LRP5	O75197-1.2	R657A	Pathogenic	0.938
LRP5	O75197-1.2	R657C	Pathogenic	0.987
LRP5	O75197-1.2	R657D	Pathogenic	0.992
LRP5	O75197-1.2	R657E	Pathogenic	0.925
LRP5	O75197-1.2	R657F	Pathogenic	0.976
LRP5	O75197-1.2	R657G	Pathogenic	0.983
LRP5	O75197-1.2	R657H	Pathogenic	0.863
LRP5	O75197-1.2	R657I	Pathogenic	0.976
LRP5	O75197-1.2	R657K	Pathogenic	0.655
LRP5	O75197-1.2	R657L	Pathogenic	0.935
LRP5	O75197-1.2	R657M	Pathogenic	0.878
LRP5	O75197-1.2	R657N	Pathogenic	0.921
LRP5	O75197-1.2	R657P	Pathogenic	0.97
LRP5	O75197-1.2	R657Q	Pathogenic	0.737
LRP5	O75197-1.2	R657S	Pathogenic	0.954
LRP5	O75197-1.2	R657T	Pathogenic	0.943
LRP5	O75197-1.2	R657V	Pathogenic	0.985
LRP5	O75197-1.2	R657W	Pathogenic	0.965
LRP5	O75197-1.2	R657Y	Pathogenic	0.966
LRP5	O75197-1.2	I658A	Pathogenic	0.982
LRP5	O75197-1.2	I658C	Pathogenic	0.99
LRP5	O75197-1.2	I658D	Pathogenic	0.995
LRP5	O75197-1.2	I658E	Pathogenic	0.996
LRP5	O75197-1.2	I658F	Pathogenic	0.986
LRP5	O75197-1.2	I658G	Pathogenic	0.999
LRP5	O75197-1.2	I658H	Pathogenic	0.998
LRP5	O75197-1.2	I658K	Pathogenic	0.994
LRP5	O75197-1.2	I658L	Pathogenic	0.878
LRP5	O75197-1.2	I658M	Pathogenic	0.935
LRP5	O75197-1.2	I658N	Pathogenic	0.996
LRP5	O75197-1.2	I658P	Pathogenic	0.999
LRP5	O75197-1.2	I658Q	Pathogenic	0.997
LRP5	O75197-1.2	I658R	Pathogenic	0.994
LRP5	O75197-1.2	I658S	Pathogenic	0.992
LRP5	O75197-1.2	I658T	Pathogenic	0.982
LRP5	O75197-1.2	I658V	Pathogenic	0.599
LRP5	O75197-1.2	I658W	Pathogenic	0.999
LRP5	O75197-1.2	I658Y	Pathogenic	0.99
LRP5	O75197-1.2	S659A	Pathogenic	0.931
LRP5	O75197-1.2	S659C	Pathogenic	0.985
LRP5	O75197-1.2	S659D	Pathogenic	0.966
LRP5	O75197-1.2	S659E	Pathogenic	0.969
LRP5	O75197-1.2	S659F	Pathogenic	0.989
LRP5	O75197-1.2	S659G	Pathogenic	0.981
LRP5	O75197-1.2	S659H	Pathogenic	0.993
LRP5	O75197-1.2	S659I	Pathogenic	0.989
LRP5	O75197-1.2	S659K	Pathogenic	0.956
LRP5	O75197-1.2	S659L	Pathogenic	0.99
LRP5	O75197-1.2	S659M	Pathogenic	0.981
LRP5	O75197-1.2	S659N	Pathogenic	0.915
LRP5	O75197-1.2	S659P	Pathogenic	0.988
LRP5	O75197-1.2	S659Q	Pathogenic	0.978
LRP5	O75197-1.2	S659R	Pathogenic	0.985
LRP5	O75197-1.2	S659T	Pathogenic	0.932
LRP5	O75197-1.2	S659V	Pathogenic	0.994
LRP5	O75197-1.2	S659W	Pathogenic	0.994
LRP5	O75197-1.2	S659Y	Pathogenic	0.995
LRP5	O75197-1.2	L660A	Pathogenic	0.933
LRP5	O75197-1.2	L660C	Pathogenic	0.963
LRP5	O75197-1.2	L660D	Pathogenic	0.994
LRP5	O75197-1.2	L660E	Pathogenic	0.983
LRP5	O75197-1.2	L660F	Pathogenic	0.941
LRP5	O75197-1.2	L660G	Pathogenic	0.997
LRP5	O75197-1.2	L660H	Pathogenic	0.992
LRP5	O75197-1.2	L660I	Pathogenic	0.633
LRP5	O75197-1.2	L660K	Pathogenic	0.935
LRP5	O75197-1.2	L660M	Pathogenic	0.555
LRP5	O75197-1.2	L660N	Pathogenic	0.984
LRP5	O75197-1.2	L660P	Pathogenic	0.995
LRP5	O75197-1.2	L660Q	Pathogenic	0.966
LRP5	O75197-1.2	L660R	Pathogenic	0.933
LRP5	O75197-1.2	L660S	Pathogenic	0.969
LRP5	O75197-1.2	L660T	Pathogenic	0.933
LRP5	O75197-1.2	L660V	Pathogenic	0.784
LRP5	O75197-1.2	L660W	Pathogenic	0.989
LRP5	O75197-1.2	L660Y	Pathogenic	0.964
LRP5	O75197-1.2	E661A	Pathogenic	0.855
LRP5	O75197-1.2	E661C	Pathogenic	0.989
LRP5	O75197-1.2	E661D	Neutral	0.311
LRP5	O75197-1.2	E661F	Pathogenic	0.937
LRP5	O75197-1.2	E661G	Pathogenic	0.958
LRP5	O75197-1.2	E661H	Pathogenic	0.706
LRP5	O75197-1.2	E661I	Pathogenic	0.937
LRP5	O75197-1.2	E661K	Pathogenic	0.527
LRP5	O75197-1.2	E661L	Pathogenic	0.943
LRP5	O75197-1.2	E661M	Pathogenic	0.891
LRP5	O75197-1.2	E661N	Pathogenic	0.821
LRP5	O75197-1.2	E661P	Pathogenic	0.809
LRP5	O75197-1.2	E661Q	Neutral	0.263
LRP5	O75197-1.2	E661R	Pathogenic	0.766
LRP5	O75197-1.2	E661S	Pathogenic	0.727
LRP5	O75197-1.2	E661T	Pathogenic	0.866
LRP5	O75197-1.2	E661V	Pathogenic	0.894
LRP5	O75197-1.2	E661W	Pathogenic	0.904
LRP5	O75197-1.2	E661Y	Pathogenic	0.911
LRP5	O75197-1.2	T662A	Pathogenic	0.888
LRP5	O75197-1.2	T662C	Pathogenic	0.932
LRP5	O75197-1.2	T662D	Pathogenic	0.913
LRP5	O75197-1.2	T662E	Pathogenic	0.92
LRP5	O75197-1.2	T662F	Pathogenic	0.95
LRP5	O75197-1.2	T662G	Pathogenic	0.983
LRP5	O75197-1.2	T662H	Pathogenic	0.986
LRP5	O75197-1.2	T662I	Pathogenic	0.863
LRP5	O75197-1.2	T662K	Pathogenic	0.89
LRP5	O75197-1.2	T662L	Pathogenic	0.873
LRP5	O75197-1.2	T662M	Pathogenic	0.913
LRP5	O75197-1.2	T662N	Pathogenic	0.8
LRP5	O75197-1.2	T662P	Pathogenic	0.946
LRP5	O75197-1.2	T662Q	Pathogenic	0.943
LRP5	O75197-1.2	T662R	Pathogenic	0.887
LRP5	O75197-1.2	T662S	Pathogenic	0.68
LRP5	O75197-1.2	T662V	Pathogenic	0.783
LRP5	O75197-1.2	T662W	Pathogenic	0.923
LRP5	O75197-1.2	T662Y	Pathogenic	0.975
LRP5	O75197-1.2	N663A	Pathogenic	0.934
LRP5	O75197-1.2	N663C	Pathogenic	0.96
LRP5	O75197-1.2	N663D	Pathogenic	0.503
LRP5	O75197-1.2	N663E	Pathogenic	0.774
LRP5	O75197-1.2	N663F	Pathogenic	0.918
LRP5	O75197-1.2	N663G	Pathogenic	0.661
LRP5	O75197-1.2	N663H	Neutral	0.373
LRP5	O75197-1.2	N663I	Pathogenic	0.919
LRP5	O75197-1.2	N663K	Pathogenic	0.705
LRP5	O75197-1.2	N663L	Pathogenic	0.925
LRP5	O75197-1.2	N663M	Pathogenic	0.861
LRP5	O75197-1.2	N663P	Pathogenic	0.91
LRP5	O75197-1.2	N663Q	Pathogenic	0.714
LRP5	O75197-1.2	N663R	Pathogenic	0.698
LRP5	O75197-1.2	N663S	Neutral	0.408
LRP5	O75197-1.2	N663T	Pathogenic	0.625
LRP5	O75197-1.2	N663V	Pathogenic	0.952
LRP5	O75197-1.2	N663W	Pathogenic	0.956
LRP5	O75197-1.2	N663Y	Pathogenic	0.885
LRP5	O75197-1.2	N664A	Pathogenic	0.948
LRP5	O75197-1.2	N664C	Pathogenic	0.969
LRP5	O75197-1.2	N664D	Pathogenic	0.567
LRP5	O75197-1.2	N664E	Pathogenic	0.816
LRP5	O75197-1.2	N664F	Pathogenic	0.936
LRP5	O75197-1.2	N664G	Pathogenic	0.717
LRP5	O75197-1.2	N664H	Neutral	0.435
LRP5	O75197-1.2	N664I	Pathogenic	0.936
LRP5	O75197-1.2	N664K	Pathogenic	0.756
LRP5	O75197-1.2	N664L	Pathogenic	0.941
LRP5	O75197-1.2	N664M	Pathogenic	0.889
LRP5	O75197-1.2	N664P	Pathogenic	0.929
LRP5	O75197-1.2	N664Q	Pathogenic	0.764
LRP5	O75197-1.2	N664R	Pathogenic	0.75
LRP5	O75197-1.2	N664S	Neutral	0.472
LRP5	O75197-1.2	N664T	Pathogenic	0.684
LRP5	O75197-1.2	N664V	Pathogenic	0.962
LRP5	O75197-1.2	N664W	Pathogenic	0.966
LRP5	O75197-1.2	N664Y	Pathogenic	0.909
LRP5	O75197-1.2	N665A	Pathogenic	0.993
LRP5	O75197-1.2	N665C	Pathogenic	0.996
LRP5	O75197-1.2	N665D	Pathogenic	0.91
LRP5	O75197-1.2	N665E	Pathogenic	0.972
LRP5	O75197-1.2	N665F	Pathogenic	0.991
LRP5	O75197-1.2	N665G	Pathogenic	0.951
LRP5	O75197-1.2	N665H	Pathogenic	0.856
LRP5	O75197-1.2	N665I	Pathogenic	0.991
LRP5	O75197-1.2	N665K	Pathogenic	0.96
LRP5	O75197-1.2	N665L	Pathogenic	0.992
LRP5	O75197-1.2	N665M	Pathogenic	0.984
LRP5	O75197-1.2	N665P	Pathogenic	0.99
LRP5	O75197-1.2	N665Q	Pathogenic	0.961
LRP5	O75197-1.2	N665R	Pathogenic	0.959
LRP5	O75197-1.2	N665S	Pathogenic	0.873
LRP5	O75197-1.2	N665T	Pathogenic	0.943
LRP5	O75197-1.2	N665V	Pathogenic	0.995
LRP5	O75197-1.2	N665W	Pathogenic	0.995
LRP5	O75197-1.2	N665Y	Pathogenic	0.987
LRP5	O75197-1.2	D666A	Pathogenic	0.705
LRP5	O75197-1.2	D666C	Pathogenic	0.804
LRP5	O75197-1.2	D666E	Neutral	0.062
LRP5	O75197-1.2	D666F	Pathogenic	0.652
LRP5	O75197-1.2	D666G	Pathogenic	0.501
LRP5	O75197-1.2	D666H	Neutral	0.478
LRP5	O75197-1.2	D666I	Pathogenic	0.653
LRP5	O75197-1.2	D666K	Pathogenic	0.621
LRP5	O75197-1.2	D666L	Pathogenic	0.862
LRP5	O75197-1.2	D666M	Pathogenic	0.758
LRP5	O75197-1.2	D666N	Neutral	0.165
LRP5	O75197-1.2	D666P	Neutral	0.361
LRP5	O75197-1.2	D666Q	Neutral	0.293
LRP5	O75197-1.2	D666R	Pathogenic	0.828
LRP5	O75197-1.2	D666S	Neutral	0.262
LRP5	O75197-1.2	D666T	Neutral	0.46
LRP5	O75197-1.2	D666V	Pathogenic	0.766
LRP5	O75197-1.2	D666W	Pathogenic	0.783
LRP5	O75197-1.2	D666Y	Pathogenic	0.795
LRP5	O75197-1.2	V667A	Pathogenic	0.779
LRP5	O75197-1.2	V667C	Pathogenic	0.953
LRP5	O75197-1.2	V667D	Pathogenic	0.975
LRP5	O75197-1.2	V667E	Pathogenic	0.937
LRP5	O75197-1.2	V667F	Pathogenic	0.936
LRP5	O75197-1.2	V667G	Pathogenic	0.986
LRP5	O75197-1.2	V667H	Pathogenic	0.989
LRP5	O75197-1.2	V667I	Neutral	0.147
LRP5	O75197-1.2	V667K	Pathogenic	0.912
LRP5	O75197-1.2	V667L	Pathogenic	0.636
LRP5	O75197-1.2	V667M	Pathogenic	0.727
LRP5	O75197-1.2	V667N	Pathogenic	0.979
LRP5	O75197-1.2	V667P	Pathogenic	0.98
LRP5	O75197-1.2	V667Q	Pathogenic	0.955
LRP5	O75197-1.2	V667R	Pathogenic	0.968
LRP5	O75197-1.2	V667S	Pathogenic	0.96
LRP5	O75197-1.2	V667T	Pathogenic	0.778
LRP5	O75197-1.2	V667W	Pathogenic	0.988
LRP5	O75197-1.2	V667Y	Pathogenic	0.951
LRP5	O75197-1.2	A668C	Pathogenic	0.649
LRP5	O75197-1.2	A668D	Pathogenic	0.922
LRP5	O75197-1.2	A668E	Pathogenic	0.81
LRP5	O75197-1.2	A668F	Pathogenic	0.885
LRP5	O75197-1.2	A668G	Pathogenic	0.72
LRP5	O75197-1.2	A668H	Pathogenic	0.962
LRP5	O75197-1.2	A668I	Pathogenic	0.717
LRP5	O75197-1.2	A668K	Pathogenic	0.749
LRP5	O75197-1.2	A668L	Pathogenic	0.736
LRP5	O75197-1.2	A668M	Pathogenic	0.809
LRP5	O75197-1.2	A668N	Pathogenic	0.932
LRP5	O75197-1.2	A668P	Pathogenic	0.876
LRP5	O75197-1.2	A668Q	Pathogenic	0.86
LRP5	O75197-1.2	A668R	Pathogenic	0.742
LRP5	O75197-1.2	A668S	Neutral	0.455
LRP5	O75197-1.2	A668T	Pathogenic	0.761
LRP5	O75197-1.2	A668V	Pathogenic	0.592
LRP5	O75197-1.2	A668W	Pathogenic	0.937
LRP5	O75197-1.2	A668Y	Pathogenic	0.941
LRP5	O75197-1.2	I669A	Pathogenic	0.982
LRP5	O75197-1.2	I669C	Pathogenic	0.99
LRP5	O75197-1.2	I669D	Pathogenic	0.995
LRP5	O75197-1.2	I669E	Pathogenic	0.996
LRP5	O75197-1.2	I669F	Pathogenic	0.987
LRP5	O75197-1.2	I669G	Pathogenic	0.999
LRP5	O75197-1.2	I669H	Pathogenic	0.998
LRP5	O75197-1.2	I669K	Pathogenic	0.994
LRP5	O75197-1.2	I669L	Pathogenic	0.882
LRP5	O75197-1.2	I669M	Pathogenic	0.937
LRP5	O75197-1.2	I669N	Pathogenic	0.996
LRP5	O75197-1.2	I669P	Pathogenic	0.999
LRP5	O75197-1.2	I669Q	Pathogenic	0.997
LRP5	O75197-1.2	I669R	Pathogenic	0.994
LRP5	O75197-1.2	I669S	Pathogenic	0.992
LRP5	O75197-1.2	I669T	Pathogenic	0.982
LRP5	O75197-1.2	I669V	Pathogenic	0.607
LRP5	O75197-1.2	I669W	Pathogenic	0.999
LRP5	O75197-1.2	I669Y	Pathogenic	0.991
LRP5	O75197-1.2	P670A	Pathogenic	0.994
LRP5	O75197-1.2	P670C	Pathogenic	0.999
LRP5	O75197-1.2	P670D	Pathogenic	0.984
LRP5	O75197-1.2	P670E	Pathogenic	0.986
LRP5	O75197-1.2	P670F	Pathogenic	1.0
LRP5	O75197-1.2	P670G	Pathogenic	0.997
LRP5	O75197-1.2	P670H	Pathogenic	0.998
LRP5	O75197-1.2	P670I	Pathogenic	0.999
LRP5	O75197-1.2	P670K	Pathogenic	0.98
LRP5	O75197-1.2	P670L	Pathogenic	0.999
LRP5	O75197-1.2	P670M	Pathogenic	0.998
LRP5	O75197-1.2	P670N	Pathogenic	0.996
LRP5	O75197-1.2	P670Q	Pathogenic	0.99
LRP5	O75197-1.2	P670R	Pathogenic	0.993
LRP5	O75197-1.2	P670S	Pathogenic	0.992
LRP5	O75197-1.2	P670T	Pathogenic	0.994
LRP5	O75197-1.2	P670V	Pathogenic	0.998
LRP5	O75197-1.2	P670W	Pathogenic	0.999
LRP5	O75197-1.2	P670Y	Pathogenic	0.999
LRP5	O75197-1.2	L671A	Pathogenic	0.857
LRP5	O75197-1.2	L671C	Pathogenic	0.919
LRP5	O75197-1.2	L671D	Pathogenic	0.985
LRP5	O75197-1.2	L671E	Pathogenic	0.962
LRP5	O75197-1.2	L671F	Pathogenic	0.872
LRP5	O75197-1.2	L671G	Pathogenic	0.992
LRP5	O75197-1.2	L671H	Pathogenic	0.981
LRP5	O75197-1.2	L671I	Neutral	0.426
LRP5	O75197-1.2	L671K	Pathogenic	0.861
LRP5	O75197-1.2	L671M	Neutral	0.348
LRP5	O75197-1.2	L671N	Pathogenic	0.963
LRP5	O75197-1.2	L671P	Pathogenic	0.988
LRP5	O75197-1.2	L671Q	Pathogenic	0.925
LRP5	O75197-1.2	L671R	Pathogenic	0.856
LRP5	O75197-1.2	L671S	Pathogenic	0.931
LRP5	O75197-1.2	L671T	Pathogenic	0.857
LRP5	O75197-1.2	L671V	Pathogenic	0.609
LRP5	O75197-1.2	L671W	Pathogenic	0.976
LRP5	O75197-1.2	L671Y	Pathogenic	0.92
LRP5	O75197-1.2	T672A	Pathogenic	0.872
LRP5	O75197-1.2	T672C	Pathogenic	0.921
LRP5	O75197-1.2	T672D	Pathogenic	0.9
LRP5	O75197-1.2	T672E	Pathogenic	0.908
LRP5	O75197-1.2	T672F	Pathogenic	0.942
LRP5	O75197-1.2	T672G	Pathogenic	0.981
LRP5	O75197-1.2	T672H	Pathogenic	0.983
LRP5	O75197-1.2	T672I	Pathogenic	0.843
LRP5	O75197-1.2	T672K	Pathogenic	0.874
LRP5	O75197-1.2	T672L	Pathogenic	0.855
LRP5	O75197-1.2	T672M	Pathogenic	0.9
LRP5	O75197-1.2	T672N	Pathogenic	0.774
LRP5	O75197-1.2	T672P	Pathogenic	0.937
LRP5	O75197-1.2	T672Q	Pathogenic	0.934
LRP5	O75197-1.2	T672R	Pathogenic	0.87
LRP5	O75197-1.2	T672S	Pathogenic	0.645
LRP5	O75197-1.2	T672V	Pathogenic	0.755
LRP5	O75197-1.2	T672W	Pathogenic	0.912
LRP5	O75197-1.2	T672Y	Pathogenic	0.971
LRP5	O75197-1.2	G673A	Pathogenic	0.983
LRP5	O75197-1.2	G673C	Pathogenic	0.999
LRP5	O75197-1.2	G673D	Pathogenic	0.991
LRP5	O75197-1.2	G673E	Pathogenic	0.997
LRP5	O75197-1.2	G673F	Pathogenic	0.997
LRP5	O75197-1.2	G673H	Pathogenic	0.998
LRP5	O75197-1.2	G673I	Pathogenic	0.999
LRP5	O75197-1.2	G673K	Pathogenic	0.996
LRP5	O75197-1.2	G673L	Pathogenic	0.999
LRP5	O75197-1.2	G673M	Pathogenic	0.998
LRP5	O75197-1.2	G673N	Pathogenic	0.977
LRP5	O75197-1.2	G673P	Pathogenic	0.997
LRP5	O75197-1.2	G673Q	Pathogenic	0.998
LRP5	O75197-1.2	G673R	Pathogenic	0.996
LRP5	O75197-1.2	G673S	Pathogenic	0.987
LRP5	O75197-1.2	G673T	Pathogenic	0.998
LRP5	O75197-1.2	G673V	Pathogenic	0.999
LRP5	O75197-1.2	G673W	Pathogenic	0.988
LRP5	O75197-1.2	G673Y	Pathogenic	0.999
LRP5	O75197-1.2	V674A	Pathogenic	0.899
LRP5	O75197-1.2	V674C	Pathogenic	0.981
LRP5	O75197-1.2	V674D	Pathogenic	0.99
LRP5	O75197-1.2	V674E	Pathogenic	0.974
LRP5	O75197-1.2	V674F	Pathogenic	0.974
LRP5	O75197-1.2	V674G	Pathogenic	0.995
LRP5	O75197-1.2	V674H	Pathogenic	0.996
LRP5	O75197-1.2	V674I	Neutral	0.304
LRP5	O75197-1.2	V674K	Pathogenic	0.963
LRP5	O75197-1.2	V674L	Pathogenic	0.816
LRP5	O75197-1.2	V674M	Pathogenic	0.871
LRP5	O75197-1.2	V674N	Pathogenic	0.992
LRP5	O75197-1.2	V674P	Pathogenic	0.992
LRP5	O75197-1.2	V674Q	Pathogenic	0.982
LRP5	O75197-1.2	V674R	Pathogenic	0.987
LRP5	O75197-1.2	V674S	Pathogenic	0.984
LRP5	O75197-1.2	V674T	Pathogenic	0.899
LRP5	O75197-1.2	V674W	Pathogenic	0.995
LRP5	O75197-1.2	V674Y	Pathogenic	0.98
LRP5	O75197-1.2	K675A	Pathogenic	0.983
LRP5	O75197-1.2	K675C	Pathogenic	0.997
LRP5	O75197-1.2	K675D	Pathogenic	0.994
LRP5	O75197-1.2	K675E	Pathogenic	0.938
LRP5	O75197-1.2	K675F	Pathogenic	0.994
LRP5	O75197-1.2	K675G	Pathogenic	0.995
LRP5	O75197-1.2	K675H	Pathogenic	0.986
LRP5	O75197-1.2	K675I	Pathogenic	0.993
LRP5	O75197-1.2	K675L	Pathogenic	0.982
LRP5	O75197-1.2	K675M	Pathogenic	0.964
LRP5	O75197-1.2	K675N	Pathogenic	0.978
LRP5	O75197-1.2	K675P	Pathogenic	0.976
LRP5	O75197-1.2	K675Q	Pathogenic	0.914
LRP5	O75197-1.2	K675R	Pathogenic	0.874
LRP5	O75197-1.2	K675S	Pathogenic	0.962
LRP5	O75197-1.2	K675T	Pathogenic	0.984
LRP5	O75197-1.2	K675V	Pathogenic	0.988
LRP5	O75197-1.2	K675W	Pathogenic	0.99
LRP5	O75197-1.2	K675Y	Pathogenic	0.991
LRP5	O75197-1.2	E676A	Pathogenic	0.942
LRP5	O75197-1.2	E676C	Pathogenic	0.996
LRP5	O75197-1.2	E676D	Pathogenic	0.552
LRP5	O75197-1.2	E676F	Pathogenic	0.976
LRP5	O75197-1.2	E676G	Pathogenic	0.984
LRP5	O75197-1.2	E676H	Pathogenic	0.868
LRP5	O75197-1.2	E676I	Pathogenic	0.976
LRP5	O75197-1.2	E676K	Pathogenic	0.753
LRP5	O75197-1.2	E676L	Pathogenic	0.978
LRP5	O75197-1.2	E676M	Pathogenic	0.957
LRP5	O75197-1.2	E676N	Pathogenic	0.926
LRP5	O75197-1.2	E676P	Pathogenic	0.921
LRP5	O75197-1.2	E676Q	Neutral	0.494
LRP5	O75197-1.2	E676R	Pathogenic	0.9
LRP5	O75197-1.2	E676S	Pathogenic	0.879
LRP5	O75197-1.2	E676T	Pathogenic	0.946
LRP5	O75197-1.2	E676V	Pathogenic	0.959
LRP5	O75197-1.2	E676W	Pathogenic	0.963
LRP5	O75197-1.2	E676Y	Pathogenic	0.965
LRP5	O75197-1.2	A677C	Pathogenic	0.959
LRP5	O75197-1.2	A677D	Pathogenic	0.993
LRP5	O75197-1.2	A677E	Pathogenic	0.982
LRP5	O75197-1.2	A677F	Pathogenic	0.99
LRP5	O75197-1.2	A677G	Pathogenic	0.97
LRP5	O75197-1.2	A677H	Pathogenic	0.997
LRP5	O75197-1.2	A677I	Pathogenic	0.97
LRP5	O75197-1.2	A677K	Pathogenic	0.974
LRP5	O75197-1.2	A677L	Pathogenic	0.972
LRP5	O75197-1.2	A677M	Pathogenic	0.982
LRP5	O75197-1.2	A677N	Pathogenic	0.994
LRP5	O75197-1.2	A677P	Pathogenic	0.989
LRP5	O75197-1.2	A677Q	Pathogenic	0.987
LRP5	O75197-1.2	A677R	Pathogenic	0.973
LRP5	O75197-1.2	A677S	Pathogenic	0.913
LRP5	O75197-1.2	A677T	Pathogenic	0.976
LRP5	O75197-1.2	A677V	Pathogenic	0.948
LRP5	O75197-1.2	A677W	Pathogenic	0.995
LRP5	O75197-1.2	A677Y	Pathogenic	0.995
LRP5	O75197-1.2	S678A	Pathogenic	0.75
LRP5	O75197-1.2	S678C	Pathogenic	0.937
LRP5	O75197-1.2	S678D	Pathogenic	0.863
LRP5	O75197-1.2	S678E	Pathogenic	0.873
LRP5	O75197-1.2	S678F	Pathogenic	0.953
LRP5	O75197-1.2	S678G	Pathogenic	0.921
LRP5	O75197-1.2	S678H	Pathogenic	0.968
LRP5	O75197-1.2	S678I	Pathogenic	0.954
LRP5	O75197-1.2	S678K	Pathogenic	0.828
LRP5	O75197-1.2	S678L	Pathogenic	0.958
LRP5	O75197-1.2	S678M	Pathogenic	0.919
LRP5	O75197-1.2	S678N	Pathogenic	0.705
LRP5	O75197-1.2	S678P	Pathogenic	0.95
LRP5	O75197-1.2	S678Q	Pathogenic	0.909
LRP5	O75197-1.2	S678R	Pathogenic	0.934
LRP5	O75197-1.2	S678T	Pathogenic	0.754
LRP5	O75197-1.2	S678V	Pathogenic	0.973
LRP5	O75197-1.2	S678W	Pathogenic	0.975
LRP5	O75197-1.2	S678Y	Pathogenic	0.977
LRP5	O75197-1.2	A679C	Pathogenic	0.971
LRP5	O75197-1.2	A679D	Pathogenic	0.995
LRP5	O75197-1.2	A679E	Pathogenic	0.987
LRP5	O75197-1.2	A679F	Pathogenic	0.993
LRP5	O75197-1.2	A679G	Pathogenic	0.979
LRP5	O75197-1.2	A679H	Pathogenic	0.998
LRP5	O75197-1.2	A679I	Pathogenic	0.979
LRP5	O75197-1.2	A679K	Pathogenic	0.982
LRP5	O75197-1.2	A679L	Pathogenic	0.98
LRP5	O75197-1.2	A679M	Pathogenic	0.987
LRP5	O75197-1.2	A679N	Pathogenic	0.996
LRP5	O75197-1.2	A679P	Pathogenic	0.992
LRP5	O75197-1.2	A679Q	Pathogenic	0.991
LRP5	O75197-1.2	A679R	Pathogenic	0.981
LRP5	O75197-1.2	A679S	Pathogenic	0.938
LRP5	O75197-1.2	A679T	Pathogenic	0.983
LRP5	O75197-1.2	A679V	Pathogenic	0.963
LRP5	O75197-1.2	A679W	Pathogenic	0.996
LRP5	O75197-1.2	A679Y	Pathogenic	0.997
LRP5	O75197-1.2	L680A	Pathogenic	0.933
LRP5	O75197-1.2	L680C	Pathogenic	0.964
LRP5	O75197-1.2	L680D	Pathogenic	0.994
LRP5	O75197-1.2	L680E	Pathogenic	0.983
LRP5	O75197-1.2	L680F	Pathogenic	0.941
LRP5	O75197-1.2	L680G	Pathogenic	0.997
LRP5	O75197-1.2	L680H	Pathogenic	0.992
LRP5	O75197-1.2	L680I	Pathogenic	0.634
LRP5	O75197-1.2	L680K	Pathogenic	0.935
LRP5	O75197-1.2	L680M	Pathogenic	0.555
LRP5	O75197-1.2	L680N	Pathogenic	0.984
LRP5	O75197-1.2	L680P	Pathogenic	0.995
LRP5	O75197-1.2	L680Q	Pathogenic	0.966
LRP5	O75197-1.2	L680R	Pathogenic	0.933
LRP5	O75197-1.2	L680S	Pathogenic	0.969
LRP5	O75197-1.2	L680T	Pathogenic	0.933
LRP5	O75197-1.2	L680V	Pathogenic	0.784
LRP5	O75197-1.2	L680W	Pathogenic	0.989
LRP5	O75197-1.2	L680Y	Pathogenic	0.964
LRP5	O75197-1.2	D681A	Pathogenic	0.995
LRP5	O75197-1.2	D681C	Pathogenic	0.997
LRP5	O75197-1.2	D681E	Pathogenic	0.843
LRP5	O75197-1.2	D681F	Pathogenic	0.993
LRP5	O75197-1.2	D681G	Pathogenic	0.988
LRP5	O75197-1.2	D681H	Pathogenic	0.987
LRP5	O75197-1.2	D681I	Pathogenic	0.994
LRP5	O75197-1.2	D681K	Pathogenic	0.993
LRP5	O75197-1.2	D681L	Pathogenic	0.998
LRP5	O75197-1.2	D681M	Pathogenic	0.996
LRP5	O75197-1.2	D681N	Pathogenic	0.941
LRP5	O75197-1.2	D681P	Pathogenic	0.979
LRP5	O75197-1.2	D681Q	Pathogenic	0.971
LRP5	O75197-1.2	D681R	Pathogenic	0.997
LRP5	O75197-1.2	D681S	Pathogenic	0.967
LRP5	O75197-1.2	D681T	Pathogenic	0.986
LRP5	O75197-1.2	D681V	Pathogenic	0.996
LRP5	O75197-1.2	D681W	Pathogenic	0.997
LRP5	O75197-1.2	D681Y	Pathogenic	0.997
LRP5	O75197-1.2	F682A	Pathogenic	0.996
LRP5	O75197-1.2	F682C	Pathogenic	0.998
LRP5	O75197-1.2	F682D	Pathogenic	0.997
LRP5	O75197-1.2	F682E	Pathogenic	0.997
LRP5	O75197-1.2	F682G	Pathogenic	0.998
LRP5	O75197-1.2	F682H	Pathogenic	0.987
LRP5	O75197-1.2	F682I	Pathogenic	0.991
LRP5	O75197-1.2	F682K	Pathogenic	0.996
LRP5	O75197-1.2	F682L	Pathogenic	0.991
LRP5	O75197-1.2	F682M	Pathogenic	0.986
LRP5	O75197-1.2	F682N	Pathogenic	0.997
LRP5	O75197-1.2	F682P	Pathogenic	1.0
LRP5	O75197-1.2	F682Q	Pathogenic	0.998
LRP5	O75197-1.2	F682R	Pathogenic	0.996
LRP5	O75197-1.2	F682S	Pathogenic	0.995
LRP5	O75197-1.2	F682T	Pathogenic	0.996
LRP5	O75197-1.2	F682V	Pathogenic	0.995
LRP5	O75197-1.2	F682W	Pathogenic	0.96
LRP5	O75197-1.2	F682Y	Pathogenic	0.659
LRP5	O75197-1.2	D683A	Pathogenic	0.971
LRP5	O75197-1.2	D683C	Pathogenic	0.983
LRP5	O75197-1.2	D683E	Neutral	0.479
LRP5	O75197-1.2	D683F	Pathogenic	0.963
LRP5	O75197-1.2	D683G	Pathogenic	0.934
LRP5	O75197-1.2	D683H	Pathogenic	0.928
LRP5	O75197-1.2	D683I	Pathogenic	0.963
LRP5	O75197-1.2	D683K	Pathogenic	0.958
LRP5	O75197-1.2	D683L	Pathogenic	0.989
LRP5	O75197-1.2	D683M	Pathogenic	0.978
LRP5	O75197-1.2	D683N	Pathogenic	0.734
LRP5	O75197-1.2	D683P	Pathogenic	0.888
LRP5	O75197-1.2	D683Q	Pathogenic	0.853
LRP5	O75197-1.2	D683R	Pathogenic	0.985
LRP5	O75197-1.2	D683S	Pathogenic	0.833
LRP5	O75197-1.2	D683T	Pathogenic	0.923
LRP5	O75197-1.2	D683V	Pathogenic	0.979
LRP5	O75197-1.2	D683W	Pathogenic	0.981
LRP5	O75197-1.2	D683Y	Pathogenic	0.982
LRP5	O75197-1.2	V684A	Pathogenic	0.682
LRP5	O75197-1.2	V684C	Pathogenic	0.925
LRP5	O75197-1.2	V684D	Pathogenic	0.96
LRP5	O75197-1.2	V684E	Pathogenic	0.9
LRP5	O75197-1.2	V684F	Pathogenic	0.899
LRP5	O75197-1.2	V684G	Pathogenic	0.978
LRP5	O75197-1.2	V684H	Pathogenic	0.982
LRP5	O75197-1.2	V684I	Neutral	0.095
LRP5	O75197-1.2	V684K	Pathogenic	0.863
LRP5	O75197-1.2	V684L	Pathogenic	0.515
LRP5	O75197-1.2	V684M	Pathogenic	0.617
LRP5	O75197-1.2	V684N	Pathogenic	0.966
LRP5	O75197-1.2	V684P	Pathogenic	0.967
LRP5	O75197-1.2	V684Q	Pathogenic	0.928
LRP5	O75197-1.2	V684R	Pathogenic	0.949
LRP5	O75197-1.2	V684S	Pathogenic	0.936
LRP5	O75197-1.2	V684T	Pathogenic	0.681
LRP5	O75197-1.2	V684W	Pathogenic	0.981
LRP5	O75197-1.2	V684Y	Pathogenic	0.921
LRP5	O75197-1.2	S685A	Neutral	0.013
LRP5	O75197-1.2	S685C	Neutral	0.061
LRP5	O75197-1.2	S685D	Neutral	0.027
LRP5	O75197-1.2	S685E	Neutral	0.029
LRP5	O75197-1.2	S685F	Neutral	0.082
LRP5	O75197-1.2	S685G	Neutral	0.048
LRP5	O75197-1.2	S685H	Neutral	0.117
LRP5	O75197-1.2	S685I	Neutral	0.082
LRP5	O75197-1.2	S685K	Neutral	0.021
LRP5	O75197-1.2	S685L	Neutral	0.09
LRP5	O75197-1.2	S685M	Neutral	0.047
LRP5	O75197-1.2	S685N	Neutral	0.01
LRP5	O75197-1.2	S685P	Neutral	0.076
LRP5	O75197-1.2	S685Q	Neutral	0.042
LRP5	O75197-1.2	S685R	Neutral	0.058
LRP5	O75197-1.2	S685T	Neutral	0.013
LRP5	O75197-1.2	S685V	Neutral	0.135
LRP5	O75197-1.2	S685W	Neutral	0.147
LRP5	O75197-1.2	S685Y	Neutral	0.157
LRP5	O75197-1.2	N686A	Neutral	0.39
LRP5	O75197-1.2	N686C	Pathogenic	0.524
LRP5	O75197-1.2	N686D	Neutral	0.044
LRP5	O75197-1.2	N686E	Neutral	0.134
LRP5	O75197-1.2	N686F	Neutral	0.338
LRP5	O75197-1.2	N686G	Neutral	0.081
LRP5	O75197-1.2	N686H	Neutral	0.026
LRP5	O75197-1.2	N686I	Neutral	0.339
LRP5	O75197-1.2	N686K	Neutral	0.098
LRP5	O75197-1.2	N686L	Neutral	0.36
LRP5	O75197-1.2	N686M	Neutral	0.219
LRP5	O75197-1.2	N686P	Neutral	0.315
LRP5	O75197-1.2	N686Q	Neutral	0.101
LRP5	O75197-1.2	N686R	Neutral	0.095
LRP5	O75197-1.2	N686S	Neutral	0.03
LRP5	O75197-1.2	N686T	Neutral	0.07
LRP5	O75197-1.2	N686V	Neutral	0.472
LRP5	O75197-1.2	N686W	Neutral	0.495
LRP5	O75197-1.2	N686Y	Neutral	0.258
LRP5	O75197-1.2	N687A	Pathogenic	0.987
LRP5	O75197-1.2	N687C	Pathogenic	0.993
LRP5	O75197-1.2	N687D	Pathogenic	0.848
LRP5	O75197-1.2	N687E	Pathogenic	0.95
LRP5	O75197-1.2	N687F	Pathogenic	0.984
LRP5	O75197-1.2	N687G	Pathogenic	0.915
LRP5	O75197-1.2	N687H	Pathogenic	0.766
LRP5	O75197-1.2	N687I	Pathogenic	0.984
LRP5	O75197-1.2	N687K	Pathogenic	0.93
LRP5	O75197-1.2	N687L	Pathogenic	0.986
LRP5	O75197-1.2	N687M	Pathogenic	0.972
LRP5	O75197-1.2	N687P	Pathogenic	0.982
LRP5	O75197-1.2	N687Q	Pathogenic	0.932
LRP5	O75197-1.2	N687R	Pathogenic	0.927
LRP5	O75197-1.2	N687S	Pathogenic	0.792
LRP5	O75197-1.2	N687T	Pathogenic	0.902
LRP5	O75197-1.2	N687V	Pathogenic	0.991
LRP5	O75197-1.2	N687W	Pathogenic	0.992
LRP5	O75197-1.2	N687Y	Pathogenic	0.977
LRP5	O75197-1.2	H688A	Pathogenic	0.94
LRP5	O75197-1.2	H688C	Pathogenic	0.964
LRP5	O75197-1.2	H688D	Pathogenic	0.737
LRP5	O75197-1.2	H688E	Pathogenic	0.516
LRP5	O75197-1.2	H688F	Pathogenic	0.591
LRP5	O75197-1.2	H688G	Pathogenic	0.941
LRP5	O75197-1.2	H688I	Pathogenic	0.931
LRP5	O75197-1.2	H688K	Pathogenic	0.7
LRP5	O75197-1.2	H688L	Pathogenic	0.937
LRP5	O75197-1.2	H688M	Pathogenic	0.881
LRP5	O75197-1.2	H688N	Neutral	0.262
LRP5	O75197-1.2	H688P	Pathogenic	0.918
LRP5	O75197-1.2	H688Q	Pathogenic	0.609
LRP5	O75197-1.2	H688R	Neutral	0.426
LRP5	O75197-1.2	H688S	Pathogenic	0.84
LRP5	O75197-1.2	H688T	Pathogenic	0.945
LRP5	O75197-1.2	H688V	Pathogenic	0.957
LRP5	O75197-1.2	H688W	Pathogenic	0.736
LRP5	O75197-1.2	H688Y	Neutral	0.097
LRP5	O75197-1.2	I689A	Pathogenic	0.97
LRP5	O75197-1.2	I689C	Pathogenic	0.984
LRP5	O75197-1.2	I689D	Pathogenic	0.992
LRP5	O75197-1.2	I689E	Pathogenic	0.993
LRP5	O75197-1.2	I689F	Pathogenic	0.977
LRP5	O75197-1.2	I689G	Pathogenic	0.998
LRP5	O75197-1.2	I689H	Pathogenic	0.996
LRP5	O75197-1.2	I689K	Pathogenic	0.99
LRP5	O75197-1.2	I689L	Pathogenic	0.812
LRP5	O75197-1.2	I689M	Pathogenic	0.896
LRP5	O75197-1.2	I689N	Pathogenic	0.993
LRP5	O75197-1.2	I689P	Pathogenic	0.998
LRP5	O75197-1.2	I689Q	Pathogenic	0.995
LRP5	O75197-1.2	I689R	Pathogenic	0.99
LRP5	O75197-1.2	I689S	Pathogenic	0.986
LRP5	O75197-1.2	I689T	Pathogenic	0.97
LRP5	O75197-1.2	I689V	Neutral	0.473
LRP5	O75197-1.2	I689W	Pathogenic	0.999
LRP5	O75197-1.2	I689Y	Pathogenic	0.984
LRP5	O75197-1.2	Y690A	Pathogenic	0.998
LRP5	O75197-1.2	Y690C	Pathogenic	0.999
LRP5	O75197-1.2	Y690D	Pathogenic	0.998
LRP5	O75197-1.2	Y690E	Pathogenic	0.995
LRP5	O75197-1.2	Y690F	Pathogenic	0.611
LRP5	O75197-1.2	Y690G	Pathogenic	0.999
LRP5	O75197-1.2	Y690H	Pathogenic	0.823
LRP5	O75197-1.2	Y690I	Pathogenic	0.992
LRP5	O75197-1.2	Y690K	Pathogenic	0.993
LRP5	O75197-1.2	Y690L	Pathogenic	0.993
LRP5	O75197-1.2	Y690M	Pathogenic	0.995
LRP5	O75197-1.2	Y690N	Pathogenic	0.995
LRP5	O75197-1.2	Y690P	Pathogenic	0.999
LRP5	O75197-1.2	Y690Q	Pathogenic	0.99
LRP5	O75197-1.2	Y690R	Pathogenic	0.993
LRP5	O75197-1.2	Y690S	Pathogenic	0.997
LRP5	O75197-1.2	Y690T	Pathogenic	0.998
LRP5	O75197-1.2	Y690V	Pathogenic	0.995
LRP5	O75197-1.2	Y690W	Pathogenic	0.755
LRP5	O75197-1.2	W691A	Pathogenic	0.999
LRP5	O75197-1.2	W691C	Pathogenic	0.999
LRP5	O75197-1.2	W691D	Pathogenic	0.999
LRP5	O75197-1.2	W691E	Pathogenic	0.998
LRP5	O75197-1.2	W691F	Pathogenic	0.985
LRP5	O75197-1.2	W691G	Pathogenic	0.997
LRP5	O75197-1.2	W691H	Pathogenic	0.998
LRP5	O75197-1.2	W691I	Pathogenic	1.0
LRP5	O75197-1.2	W691K	Pathogenic	0.998
LRP5	O75197-1.2	W691L	Pathogenic	0.999
LRP5	O75197-1.2	W691M	Pathogenic	0.997
LRP5	O75197-1.2	W691N	Pathogenic	0.999
LRP5	O75197-1.2	W691P	Pathogenic	1.0
LRP5	O75197-1.2	W691Q	Pathogenic	0.997
LRP5	O75197-1.2	W691R	Pathogenic	0.998
LRP5	O75197-1.2	W691S	Pathogenic	0.999
LRP5	O75197-1.2	W691T	Pathogenic	0.998
LRP5	O75197-1.2	W691V	Pathogenic	1.0
LRP5	O75197-1.2	W691Y	Pathogenic	0.913
LRP5	O75197-1.2	T692A	Pathogenic	0.975
LRP5	O75197-1.2	T692C	Pathogenic	0.985
LRP5	O75197-1.2	T692D	Pathogenic	0.981
LRP5	O75197-1.2	T692E	Pathogenic	0.983
LRP5	O75197-1.2	T692F	Pathogenic	0.989
LRP5	O75197-1.2	T692G	Pathogenic	0.997
LRP5	O75197-1.2	T692H	Pathogenic	0.997
LRP5	O75197-1.2	T692I	Pathogenic	0.969
LRP5	O75197-1.2	T692K	Pathogenic	0.976
LRP5	O75197-1.2	T692L	Pathogenic	0.971
LRP5	O75197-1.2	T692M	Pathogenic	0.981
LRP5	O75197-1.2	T692N	Pathogenic	0.952
LRP5	O75197-1.2	T692P	Pathogenic	0.988
LRP5	O75197-1.2	T692Q	Pathogenic	0.988
LRP5	O75197-1.2	T692R	Pathogenic	0.975
LRP5	O75197-1.2	T692S	Pathogenic	0.913
LRP5	O75197-1.2	T692V	Pathogenic	0.947
LRP5	O75197-1.2	T692W	Pathogenic	0.983
LRP5	O75197-1.2	T692Y	Pathogenic	0.995
LRP5	O75197-1.2	D693A	Pathogenic	0.992
LRP5	O75197-1.2	D693C	Pathogenic	0.996
LRP5	O75197-1.2	D693E	Pathogenic	0.782
LRP5	O75197-1.2	D693F	Pathogenic	0.99
LRP5	O75197-1.2	D693G	Pathogenic	0.982
LRP5	O75197-1.2	D693H	Pathogenic	0.98
LRP5	O75197-1.2	D693I	Pathogenic	0.99
LRP5	O75197-1.2	D693K	Pathogenic	0.989
LRP5	O75197-1.2	D693L	Pathogenic	0.997
LRP5	O75197-1.2	D693M	Pathogenic	0.994
LRP5	O75197-1.2	D693N	Pathogenic	0.915
LRP5	O75197-1.2	D693P	Pathogenic	0.969
LRP5	O75197-1.2	D693Q	Pathogenic	0.958
LRP5	O75197-1.2	D693R	Pathogenic	0.996
LRP5	O75197-1.2	D693S	Pathogenic	0.951
LRP5	O75197-1.2	D693T	Pathogenic	0.979
LRP5	O75197-1.2	D693V	Pathogenic	0.994
LRP5	O75197-1.2	D693W	Pathogenic	0.995
LRP5	O75197-1.2	D693Y	Pathogenic	0.995
LRP5	O75197-1.2	V694A	Neutral	0.312
LRP5	O75197-1.2	V694C	Pathogenic	0.722
LRP5	O75197-1.2	V694D	Pathogenic	0.835
LRP5	O75197-1.2	V694E	Pathogenic	0.656
LRP5	O75197-1.2	V694F	Pathogenic	0.654
LRP5	O75197-1.2	V694G	Pathogenic	0.904
LRP5	O75197-1.2	V694H	Pathogenic	0.919
LRP5	O75197-1.2	V694I	Neutral	0.022
LRP5	O75197-1.2	V694K	Pathogenic	0.571
LRP5	O75197-1.2	V694L	Neutral	0.184
LRP5	O75197-1.2	V694M	Neutral	0.255
LRP5	O75197-1.2	V694N	Pathogenic	0.856
LRP5	O75197-1.2	V694P	Pathogenic	0.863
LRP5	O75197-1.2	V694Q	Pathogenic	0.733
LRP5	O75197-1.2	V694R	Pathogenic	0.797
LRP5	O75197-1.2	V694S	Pathogenic	0.757
LRP5	O75197-1.2	V694T	Neutral	0.311
LRP5	O75197-1.2	V694W	Pathogenic	0.917
LRP5	O75197-1.2	V694Y	Pathogenic	0.713
LRP5	O75197-1.2	S695A	Neutral	0.096
LRP5	O75197-1.2	S695C	Neutral	0.346
LRP5	O75197-1.2	S695D	Neutral	0.182
LRP5	O75197-1.2	S695E	Neutral	0.196
LRP5	O75197-1.2	S695F	Neutral	0.42
LRP5	O75197-1.2	S695G	Neutral	0.291
LRP5	O75197-1.2	S695H	Pathogenic	0.518
LRP5	O75197-1.2	S695I	Neutral	0.421
LRP5	O75197-1.2	S695K	Neutral	0.146
LRP5	O75197-1.2	S695L	Neutral	0.444
LRP5	O75197-1.2	S695M	Neutral	0.285
LRP5	O75197-1.2	S695N	Neutral	0.078
LRP5	O75197-1.2	S695P	Neutral	0.4
LRP5	O75197-1.2	S695Q	Neutral	0.26
LRP5	O75197-1.2	S695R	Neutral	0.334
LRP5	O75197-1.2	S695T	Neutral	0.098
LRP5	O75197-1.2	S695V	Pathogenic	0.559
LRP5	O75197-1.2	S695W	Pathogenic	0.582
LRP5	O75197-1.2	S695Y	Pathogenic	0.601
LRP5	O75197-1.2	L696A	Neutral	0.471
LRP5	O75197-1.2	L696C	Pathogenic	0.627
LRP5	O75197-1.2	L696D	Pathogenic	0.909
LRP5	O75197-1.2	L696E	Pathogenic	0.791
LRP5	O75197-1.2	L696F	Pathogenic	0.503
LRP5	O75197-1.2	L696G	Pathogenic	0.949
LRP5	O75197-1.2	L696H	Pathogenic	0.884
LRP5	O75197-1.2	L696I	Neutral	0.099
LRP5	O75197-1.2	L696K	Neutral	0.478
LRP5	O75197-1.2	L696M	Neutral	0.073
LRP5	O75197-1.2	L696N	Pathogenic	0.793
LRP5	O75197-1.2	L696P	Pathogenic	0.925
LRP5	O75197-1.2	L696Q	Pathogenic	0.646
LRP5	O75197-1.2	L696R	Neutral	0.469
LRP5	O75197-1.2	L696S	Pathogenic	0.668
LRP5	O75197-1.2	L696T	Neutral	0.47
LRP5	O75197-1.2	L696V	Neutral	0.187
LRP5	O75197-1.2	L696W	Pathogenic	0.856
LRP5	O75197-1.2	L696Y	Pathogenic	0.63
LRP5	O75197-1.2	K697A	Pathogenic	0.986
LRP5	O75197-1.2	K697C	Pathogenic	0.997
LRP5	O75197-1.2	K697D	Pathogenic	0.995
LRP5	O75197-1.2	K697E	Pathogenic	0.951
LRP5	O75197-1.2	K697F	Pathogenic	0.995
LRP5	O75197-1.2	K697G	Pathogenic	0.996
LRP5	O75197-1.2	K697H	Pathogenic	0.989
LRP5	O75197-1.2	K697I	Pathogenic	0.995
LRP5	O75197-1.2	K697L	Pathogenic	0.986
LRP5	O75197-1.2	K697M	Pathogenic	0.972
LRP5	O75197-1.2	K697N	Pathogenic	0.982
LRP5	O75197-1.2	K697P	Pathogenic	0.981
LRP5	O75197-1.2	K697Q	Pathogenic	0.93
LRP5	O75197-1.2	K697R	Pathogenic	0.897
LRP5	O75197-1.2	K697S	Pathogenic	0.97
LRP5	O75197-1.2	K697T	Pathogenic	0.987
LRP5	O75197-1.2	K697V	Pathogenic	0.99
LRP5	O75197-1.2	K697W	Pathogenic	0.992
LRP5	O75197-1.2	K697Y	Pathogenic	0.993
LRP5	O75197-1.2	T698A	Pathogenic	0.909
LRP5	O75197-1.2	T698C	Pathogenic	0.945
LRP5	O75197-1.2	T698D	Pathogenic	0.93
LRP5	O75197-1.2	T698E	Pathogenic	0.936
LRP5	O75197-1.2	T698F	Pathogenic	0.96
LRP5	O75197-1.2	T698G	Pathogenic	0.987
LRP5	O75197-1.2	T698H	Pathogenic	0.989
LRP5	O75197-1.2	T698I	Pathogenic	0.888
LRP5	O75197-1.2	T698K	Pathogenic	0.911
LRP5	O75197-1.2	T698L	Pathogenic	0.897
LRP5	O75197-1.2	T698M	Pathogenic	0.93
LRP5	O75197-1.2	T698N	Pathogenic	0.835
LRP5	O75197-1.2	T698P	Pathogenic	0.956
LRP5	O75197-1.2	T698Q	Pathogenic	0.954
LRP5	O75197-1.2	T698R	Pathogenic	0.908
LRP5	O75197-1.2	T698S	Pathogenic	0.728
LRP5	O75197-1.2	T698V	Pathogenic	0.819
LRP5	O75197-1.2	T698W	Pathogenic	0.938
LRP5	O75197-1.2	T698Y	Pathogenic	0.98
LRP5	O75197-1.2	I699A	Pathogenic	0.991
LRP5	O75197-1.2	I699C	Pathogenic	0.995
LRP5	O75197-1.2	I699D	Pathogenic	0.997
LRP5	O75197-1.2	I699E	Pathogenic	0.998
LRP5	O75197-1.2	I699F	Pathogenic	0.993
LRP5	O75197-1.2	I699G	Pathogenic	1.0
LRP5	O75197-1.2	I699H	Pathogenic	0.999
LRP5	O75197-1.2	I699K	Pathogenic	0.997
LRP5	O75197-1.2	I699L	Pathogenic	0.935
LRP5	O75197-1.2	I699M	Pathogenic	0.966
LRP5	O75197-1.2	I699N	Pathogenic	0.998
LRP5	O75197-1.2	I699P	Pathogenic	0.999
LRP5	O75197-1.2	I699Q	Pathogenic	0.998
LRP5	O75197-1.2	I699R	Pathogenic	0.997
LRP5	O75197-1.2	I699S	Pathogenic	0.996
LRP5	O75197-1.2	I699T	Pathogenic	0.991
LRP5	O75197-1.2	I699V	Pathogenic	0.747
LRP5	O75197-1.2	I699W	Pathogenic	1.0
LRP5	O75197-1.2	I699Y	Pathogenic	0.995
LRP5	O75197-1.2	S700A	Pathogenic	0.812
LRP5	O75197-1.2	S700C	Pathogenic	0.956
LRP5	O75197-1.2	S700D	Pathogenic	0.901
LRP5	O75197-1.2	S700E	Pathogenic	0.909
LRP5	O75197-1.2	S700F	Pathogenic	0.967
LRP5	O75197-1.2	S700G	Pathogenic	0.944
LRP5	O75197-1.2	S700H	Pathogenic	0.978
LRP5	O75197-1.2	S700I	Pathogenic	0.967
LRP5	O75197-1.2	S700K	Pathogenic	0.875
LRP5	O75197-1.2	S700L	Pathogenic	0.97
LRP5	O75197-1.2	S700M	Pathogenic	0.942
LRP5	O75197-1.2	S700N	Pathogenic	0.776
LRP5	O75197-1.2	S700P	Pathogenic	0.965
LRP5	O75197-1.2	S700Q	Pathogenic	0.935
LRP5	O75197-1.2	S700R	Pathogenic	0.954
LRP5	O75197-1.2	S700T	Pathogenic	0.816
LRP5	O75197-1.2	S700V	Pathogenic	0.981
LRP5	O75197-1.2	S700W	Pathogenic	0.983
LRP5	O75197-1.2	S700Y	Pathogenic	0.984
LRP5	O75197-1.2	R701A	Pathogenic	0.992
LRP5	O75197-1.2	R701C	Pathogenic	0.998
LRP5	O75197-1.2	R701D	Pathogenic	0.999
LRP5	O75197-1.2	R701E	Pathogenic	0.99
LRP5	O75197-1.2	R701F	Pathogenic	0.997
LRP5	O75197-1.2	R701G	Pathogenic	0.998
LRP5	O75197-1.2	R701H	Pathogenic	0.981
LRP5	O75197-1.2	R701I	Pathogenic	0.997
LRP5	O75197-1.2	R701K	Pathogenic	0.938
LRP5	O75197-1.2	R701L	Pathogenic	0.991
LRP5	O75197-1.2	R701M	Pathogenic	0.983
LRP5	O75197-1.2	R701N	Pathogenic	0.989
LRP5	O75197-1.2	R701P	Pathogenic	0.996
LRP5	O75197-1.2	R701Q	Pathogenic	0.958
LRP5	O75197-1.2	R701S	Pathogenic	0.994
LRP5	O75197-1.2	R701T	Pathogenic	0.992
LRP5	O75197-1.2	R701V	Pathogenic	0.998
LRP5	O75197-1.2	R701W	Pathogenic	0.995
LRP5	O75197-1.2	R701Y	Pathogenic	0.996
LRP5	O75197-1.2	A702C	Pathogenic	0.979
LRP5	O75197-1.2	A702D	Pathogenic	0.997
LRP5	O75197-1.2	A702E	Pathogenic	0.991
LRP5	O75197-1.2	A702F	Pathogenic	0.995
LRP5	O75197-1.2	A702G	Pathogenic	0.985
LRP5	O75197-1.2	A702H	Pathogenic	0.998
LRP5	O75197-1.2	A702I	Pathogenic	0.985
LRP5	O75197-1.2	A702K	Pathogenic	0.987
LRP5	O75197-1.2	A702L	Pathogenic	0.986
LRP5	O75197-1.2	A702M	Pathogenic	0.991
LRP5	O75197-1.2	A702N	Pathogenic	0.997
LRP5	O75197-1.2	A702P	Pathogenic	0.994
LRP5	O75197-1.2	A702Q	Pathogenic	0.994
LRP5	O75197-1.2	A702R	Pathogenic	0.987
LRP5	O75197-1.2	A702S	Pathogenic	0.955
LRP5	O75197-1.2	A702T	Pathogenic	0.988
LRP5	O75197-1.2	A702V	Pathogenic	0.974
LRP5	O75197-1.2	A702W	Pathogenic	0.997
LRP5	O75197-1.2	A702Y	Pathogenic	0.998
LRP5	O75197-1.2	F703A	Pathogenic	0.996
LRP5	O75197-1.2	F703C	Pathogenic	0.998
LRP5	O75197-1.2	F703D	Pathogenic	0.997
LRP5	O75197-1.2	F703E	Pathogenic	0.997
LRP5	O75197-1.2	F703G	Pathogenic	0.998
LRP5	O75197-1.2	F703H	Pathogenic	0.988
LRP5	O75197-1.2	F703I	Pathogenic	0.991
LRP5	O75197-1.2	F703K	Pathogenic	0.996
LRP5	O75197-1.2	F703L	Pathogenic	0.991
LRP5	O75197-1.2	F703M	Pathogenic	0.986
LRP5	O75197-1.2	F703N	Pathogenic	0.997
LRP5	O75197-1.2	F703P	Pathogenic	1.0
LRP5	O75197-1.2	F703Q	Pathogenic	0.998
LRP5	O75197-1.2	F703R	Pathogenic	0.996
LRP5	O75197-1.2	F703S	Pathogenic	0.995
LRP5	O75197-1.2	F703T	Pathogenic	0.996
LRP5	O75197-1.2	F703V	Pathogenic	0.995
LRP5	O75197-1.2	F703W	Pathogenic	0.961
LRP5	O75197-1.2	F703Y	Pathogenic	0.664
LRP5	O75197-1.2	M704A	Pathogenic	0.992
LRP5	O75197-1.2	M704C	Pathogenic	0.996
LRP5	O75197-1.2	M704D	Pathogenic	0.998
LRP5	O75197-1.2	M704E	Pathogenic	0.995
LRP5	O75197-1.2	M704F	Pathogenic	0.985
LRP5	O75197-1.2	M704G	Pathogenic	0.999
LRP5	O75197-1.2	M704H	Pathogenic	0.997
LRP5	O75197-1.2	M704I	Pathogenic	0.955
LRP5	O75197-1.2	M704K	Pathogenic	0.978
LRP5	O75197-1.2	M704L	Pathogenic	0.883
LRP5	O75197-1.2	M704N	Pathogenic	0.995
LRP5	O75197-1.2	M704P	Pathogenic	0.998
LRP5	O75197-1.2	M704Q	Pathogenic	0.966
LRP5	O75197-1.2	M704R	Pathogenic	0.977
LRP5	O75197-1.2	M704S	Pathogenic	0.99
LRP5	O75197-1.2	M704T	Pathogenic	0.992
LRP5	O75197-1.2	M704V	Pathogenic	0.971
LRP5	O75197-1.2	M704W	Pathogenic	0.992
LRP5	O75197-1.2	M704Y	Pathogenic	0.996
LRP5	O75197-1.2	N705A	Pathogenic	0.999
LRP5	O75197-1.2	N705C	Pathogenic	0.999
LRP5	O75197-1.2	N705D	Pathogenic	0.984
LRP5	O75197-1.2	N705E	Pathogenic	0.995
LRP5	O75197-1.2	N705F	Pathogenic	0.999
LRP5	O75197-1.2	N705G	Pathogenic	0.992
LRP5	O75197-1.2	N705H	Pathogenic	0.974
LRP5	O75197-1.2	N705I	Pathogenic	0.999
LRP5	O75197-1.2	N705K	Pathogenic	0.993
LRP5	O75197-1.2	N705L	Pathogenic	0.999
LRP5	O75197-1.2	N705M	Pathogenic	0.997
LRP5	O75197-1.2	N705P	Pathogenic	0.998
LRP5	O75197-1.2	N705Q	Pathogenic	0.994
LRP5	O75197-1.2	N705R	Pathogenic	0.993
LRP5	O75197-1.2	N705S	Pathogenic	0.977
LRP5	O75197-1.2	N705T	Pathogenic	0.99
LRP5	O75197-1.2	N705V	Pathogenic	0.999
LRP5	O75197-1.2	N705W	Pathogenic	0.999
LRP5	O75197-1.2	N705Y	Pathogenic	0.998
LRP5	O75197-1.2	G706A	Pathogenic	0.989
LRP5	O75197-1.2	G706C	Pathogenic	0.999
LRP5	O75197-1.2	G706D	Pathogenic	0.994
LRP5	O75197-1.2	G706E	Pathogenic	0.998
LRP5	O75197-1.2	G706F	Pathogenic	0.998
LRP5	O75197-1.2	G706H	Pathogenic	0.999
LRP5	O75197-1.2	G706I	Pathogenic	0.999
LRP5	O75197-1.2	G706K	Pathogenic	0.998
LRP5	O75197-1.2	G706L	Pathogenic	1.0
LRP5	O75197-1.2	G706M	Pathogenic	0.999
LRP5	O75197-1.2	G706N	Pathogenic	0.985
LRP5	O75197-1.2	G706P	Pathogenic	0.998
LRP5	O75197-1.2	G706Q	Pathogenic	0.999
LRP5	O75197-1.2	G706R	Pathogenic	0.997
LRP5	O75197-1.2	G706S	Pathogenic	0.991
LRP5	O75197-1.2	G706T	Pathogenic	0.999
LRP5	O75197-1.2	G706V	Pathogenic	0.999
LRP5	O75197-1.2	G706W	Pathogenic	0.992
LRP5	O75197-1.2	G706Y	Pathogenic	0.999
LRP5	O75197-1.2	S707A	Pathogenic	0.962
LRP5	O75197-1.2	S707C	Pathogenic	0.992
LRP5	O75197-1.2	S707D	Pathogenic	0.982
LRP5	O75197-1.2	S707E	Pathogenic	0.983
LRP5	O75197-1.2	S707F	Pathogenic	0.994
LRP5	O75197-1.2	S707G	Pathogenic	0.99
LRP5	O75197-1.2	S707H	Pathogenic	0.996
LRP5	O75197-1.2	S707I	Pathogenic	0.994
LRP5	O75197-1.2	S707K	Pathogenic	0.976
LRP5	O75197-1.2	S707L	Pathogenic	0.995
LRP5	O75197-1.2	S707M	Pathogenic	0.99
LRP5	O75197-1.2	S707N	Pathogenic	0.953
LRP5	O75197-1.2	S707P	Pathogenic	0.994
LRP5	O75197-1.2	S707Q	Pathogenic	0.988
LRP5	O75197-1.2	S707R	Pathogenic	0.992
LRP5	O75197-1.2	S707T	Pathogenic	0.963
LRP5	O75197-1.2	S707V	Pathogenic	0.997
LRP5	O75197-1.2	S707W	Pathogenic	0.997
LRP5	O75197-1.2	S707Y	Pathogenic	0.997
LRP5	O75197-1.2	S708A	Neutral	0.061
LRP5	O75197-1.2	S708C	Neutral	0.245
LRP5	O75197-1.2	S708D	Neutral	0.12
LRP5	O75197-1.2	S708E	Neutral	0.13
LRP5	O75197-1.2	S708F	Neutral	0.307
LRP5	O75197-1.2	S708G	Neutral	0.201
LRP5	O75197-1.2	S708H	Neutral	0.397
LRP5	O75197-1.2	S708I	Neutral	0.308
LRP5	O75197-1.2	S708K	Neutral	0.095
LRP5	O75197-1.2	S708L	Neutral	0.328
LRP5	O75197-1.2	S708M	Neutral	0.196
LRP5	O75197-1.2	S708N	Neutral	0.049
LRP5	O75197-1.2	S708P	Neutral	0.29
LRP5	O75197-1.2	S708Q	Neutral	0.177
LRP5	O75197-1.2	S708R	Neutral	0.235
LRP5	O75197-1.2	S708T	Neutral	0.062
LRP5	O75197-1.2	S708V	Neutral	0.437
LRP5	O75197-1.2	S708W	Neutral	0.461
LRP5	O75197-1.2	S708Y	Neutral	0.48
LRP5	O75197-1.2	V709A	Neutral	0.14
LRP5	O75197-1.2	V709C	Neutral	0.484
LRP5	O75197-1.2	V709D	Pathogenic	0.646
LRP5	O75197-1.2	V709E	Neutral	0.407
LRP5	O75197-1.2	V709F	Neutral	0.405
LRP5	O75197-1.2	V709G	Pathogenic	0.772
LRP5	O75197-1.2	V709H	Pathogenic	0.804
LRP5	O75197-1.2	V709I	Neutral	0.008
LRP5	O75197-1.2	V709K	Neutral	0.324
LRP5	O75197-1.2	V709L	Neutral	0.075
LRP5	O75197-1.2	V709M	Neutral	0.11
LRP5	O75197-1.2	V709N	Pathogenic	0.681
LRP5	O75197-1.2	V709P	Pathogenic	0.694
LRP5	O75197-1.2	V709Q	Neutral	0.497
LRP5	O75197-1.2	V709R	Pathogenic	0.585
LRP5	O75197-1.2	V709S	Pathogenic	0.529
LRP5	O75197-1.2	V709T	Neutral	0.14
LRP5	O75197-1.2	V709W	Pathogenic	0.799
LRP5	O75197-1.2	V709Y	Neutral	0.472
LRP5	O75197-1.2	E710A	Pathogenic	0.991
LRP5	O75197-1.2	E710C	Pathogenic	0.999
LRP5	O75197-1.2	E710D	Pathogenic	0.891
LRP5	O75197-1.2	E710F	Pathogenic	0.996
LRP5	O75197-1.2	E710G	Pathogenic	0.998
LRP5	O75197-1.2	E710H	Pathogenic	0.977
LRP5	O75197-1.2	E710I	Pathogenic	0.996
LRP5	O75197-1.2	E710K	Pathogenic	0.953
LRP5	O75197-1.2	E710L	Pathogenic	0.997
LRP5	O75197-1.2	E710M	Pathogenic	0.993
LRP5	O75197-1.2	E710N	Pathogenic	0.988
LRP5	O75197-1.2	E710P	Pathogenic	0.987
LRP5	O75197-1.2	E710Q	Pathogenic	0.866
LRP5	O75197-1.2	E710R	Pathogenic	0.983
LRP5	O75197-1.2	E710S	Pathogenic	0.98
LRP5	O75197-1.2	E710T	Pathogenic	0.992
LRP5	O75197-1.2	E710V	Pathogenic	0.994
LRP5	O75197-1.2	E710W	Pathogenic	0.994
LRP5	O75197-1.2	E710Y	Pathogenic	0.995
LRP5	O75197-1.2	H711A	Pathogenic	0.996
LRP5	O75197-1.2	H711C	Pathogenic	0.997
LRP5	O75197-1.2	H711D	Pathogenic	0.976
LRP5	O75197-1.2	H711E	Pathogenic	0.94
LRP5	O75197-1.2	H711F	Pathogenic	0.955
LRP5	O75197-1.2	H711G	Pathogenic	0.996
LRP5	O75197-1.2	H711I	Pathogenic	0.995
LRP5	O75197-1.2	H711K	Pathogenic	0.972
LRP5	O75197-1.2	H711L	Pathogenic	0.995
LRP5	O75197-1.2	H711M	Pathogenic	0.991
LRP5	O75197-1.2	H711N	Pathogenic	0.838
LRP5	O75197-1.2	H711P	Pathogenic	0.994
LRP5	O75197-1.2	H711Q	Pathogenic	0.958
LRP5	O75197-1.2	H711R	Pathogenic	0.916
LRP5	O75197-1.2	H711S	Pathogenic	0.987
LRP5	O75197-1.2	H711T	Pathogenic	0.996
LRP5	O75197-1.2	H711V	Pathogenic	0.997
LRP5	O75197-1.2	H711W	Pathogenic	0.976
LRP5	O75197-1.2	H711Y	Pathogenic	0.61
LRP5	O75197-1.2	V712A	Pathogenic	0.912
LRP5	O75197-1.2	V712C	Pathogenic	0.983
LRP5	O75197-1.2	V712D	Pathogenic	0.991
LRP5	O75197-1.2	V712E	Pathogenic	0.978
LRP5	O75197-1.2	V712F	Pathogenic	0.977
LRP5	O75197-1.2	V712G	Pathogenic	0.995
LRP5	O75197-1.2	V712H	Pathogenic	0.996
LRP5	O75197-1.2	V712I	Neutral	0.337
LRP5	O75197-1.2	V712K	Pathogenic	0.968
LRP5	O75197-1.2	V712L	Pathogenic	0.837
LRP5	O75197-1.2	V712M	Pathogenic	0.887
LRP5	O75197-1.2	V712N	Pathogenic	0.993
LRP5	O75197-1.2	V712P	Pathogenic	0.993
LRP5	O75197-1.2	V712Q	Pathogenic	0.984
LRP5	O75197-1.2	V712R	Pathogenic	0.989
LRP5	O75197-1.2	V712S	Pathogenic	0.986
LRP5	O75197-1.2	V712T	Pathogenic	0.912
LRP5	O75197-1.2	V712W	Pathogenic	0.996
LRP5	O75197-1.2	V712Y	Pathogenic	0.983
LRP5	O75197-1.2	V713A	Pathogenic	0.653
LRP5	O75197-1.2	V713C	Pathogenic	0.915
LRP5	O75197-1.2	V713D	Pathogenic	0.955
LRP5	O75197-1.2	V713E	Pathogenic	0.888
LRP5	O75197-1.2	V713F	Pathogenic	0.887
LRP5	O75197-1.2	V713G	Pathogenic	0.975
LRP5	O75197-1.2	V713H	Pathogenic	0.979
LRP5	O75197-1.2	V713I	Neutral	0.084
LRP5	O75197-1.2	V713K	Pathogenic	0.847
LRP5	O75197-1.2	V713L	Neutral	0.483
LRP5	O75197-1.2	V713M	Pathogenic	0.587
LRP5	O75197-1.2	V713N	Pathogenic	0.961
LRP5	O75197-1.2	V713P	Pathogenic	0.963
LRP5	O75197-1.2	V713Q	Pathogenic	0.919
LRP5	O75197-1.2	V713R	Pathogenic	0.942
LRP5	O75197-1.2	V713S	Pathogenic	0.928
LRP5	O75197-1.2	V713T	Pathogenic	0.652
LRP5	O75197-1.2	V713W	Pathogenic	0.979
LRP5	O75197-1.2	V713Y	Pathogenic	0.911
LRP5	O75197-1.2	E714A	Pathogenic	0.945
LRP5	O75197-1.2	E714C	Pathogenic	0.996
LRP5	O75197-1.2	E714D	Pathogenic	0.57
LRP5	O75197-1.2	E714F	Pathogenic	0.978
LRP5	O75197-1.2	E714G	Pathogenic	0.985
LRP5	O75197-1.2	E714H	Pathogenic	0.875
LRP5	O75197-1.2	E714I	Pathogenic	0.978
LRP5	O75197-1.2	E714K	Pathogenic	0.766
LRP5	O75197-1.2	E714L	Pathogenic	0.98
LRP5	O75197-1.2	E714M	Pathogenic	0.96
LRP5	O75197-1.2	E714N	Pathogenic	0.931
LRP5	O75197-1.2	E714P	Pathogenic	0.926
LRP5	O75197-1.2	E714Q	Pathogenic	0.511
LRP5	O75197-1.2	E714R	Pathogenic	0.906
LRP5	O75197-1.2	E714S	Pathogenic	0.887
LRP5	O75197-1.2	E714T	Pathogenic	0.95
LRP5	O75197-1.2	E714V	Pathogenic	0.961
LRP5	O75197-1.2	E714W	Pathogenic	0.965
LRP5	O75197-1.2	E714Y	Pathogenic	0.968
LRP5	O75197-1.2	F715A	Pathogenic	0.992
LRP5	O75197-1.2	F715C	Pathogenic	0.996
LRP5	O75197-1.2	F715D	Pathogenic	0.993
LRP5	O75197-1.2	F715E	Pathogenic	0.994
LRP5	O75197-1.2	F715G	Pathogenic	0.996
LRP5	O75197-1.2	F715H	Pathogenic	0.975
LRP5	O75197-1.2	F715I	Pathogenic	0.982
LRP5	O75197-1.2	F715K	Pathogenic	0.993
LRP5	O75197-1.2	F715L	Pathogenic	0.981
LRP5	O75197-1.2	F715M	Pathogenic	0.971
LRP5	O75197-1.2	F715N	Pathogenic	0.994
LRP5	O75197-1.2	F715P	Pathogenic	0.999
LRP5	O75197-1.2	F715Q	Pathogenic	0.996
LRP5	O75197-1.2	F715R	Pathogenic	0.992
LRP5	O75197-1.2	F715S	Pathogenic	0.989
LRP5	O75197-1.2	F715T	Pathogenic	0.992
LRP5	O75197-1.2	F715V	Pathogenic	0.99
LRP5	O75197-1.2	F715W	Pathogenic	0.922
LRP5	O75197-1.2	F715Y	Neutral	0.488
LRP5	O75197-1.2	G716A	Pathogenic	0.984
LRP5	O75197-1.2	G716C	Pathogenic	0.999
LRP5	O75197-1.2	G716D	Pathogenic	0.992
LRP5	O75197-1.2	G716E	Pathogenic	0.997
LRP5	O75197-1.2	G716F	Pathogenic	0.998
LRP5	O75197-1.2	G716H	Pathogenic	0.998
LRP5	O75197-1.2	G716I	Pathogenic	0.999
LRP5	O75197-1.2	G716K	Pathogenic	0.996
LRP5	O75197-1.2	G716L	Pathogenic	0.999
LRP5	O75197-1.2	G716M	Pathogenic	0.999
LRP5	O75197-1.2	G716N	Pathogenic	0.978
LRP5	O75197-1.2	G716P	Pathogenic	0.997
LRP5	O75197-1.2	G716Q	Pathogenic	0.998
LRP5	O75197-1.2	G716R	Pathogenic	0.996
LRP5	O75197-1.2	G716S	Pathogenic	0.987
LRP5	O75197-1.2	G716T	Pathogenic	0.998
LRP5	O75197-1.2	G716V	Pathogenic	0.999
LRP5	O75197-1.2	G716W	Pathogenic	0.988
LRP5	O75197-1.2	G716Y	Pathogenic	0.999
LRP5	O75197-1.2	L717A	Pathogenic	0.983
LRP5	O75197-1.2	L717C	Pathogenic	0.991
LRP5	O75197-1.2	L717D	Pathogenic	0.998
LRP5	O75197-1.2	L717E	Pathogenic	0.996
LRP5	O75197-1.2	L717F	Pathogenic	0.985
LRP5	O75197-1.2	L717G	Pathogenic	0.999
LRP5	O75197-1.2	L717H	Pathogenic	0.998
LRP5	O75197-1.2	L717I	Pathogenic	0.877
LRP5	O75197-1.2	L717K	Pathogenic	0.983
LRP5	O75197-1.2	L717M	Pathogenic	0.838
LRP5	O75197-1.2	L717N	Pathogenic	0.996
LRP5	O75197-1.2	L717P	Pathogenic	0.999
LRP5	O75197-1.2	L717Q	Pathogenic	0.992
LRP5	O75197-1.2	L717R	Pathogenic	0.983
LRP5	O75197-1.2	L717S	Pathogenic	0.992
LRP5	O75197-1.2	L717T	Pathogenic	0.983
LRP5	O75197-1.2	L717V	Pathogenic	0.938
LRP5	O75197-1.2	L717W	Pathogenic	0.997
LRP5	O75197-1.2	L717Y	Pathogenic	0.991
LRP5	O75197-1.2	D718A	Pathogenic	0.982
LRP5	O75197-1.2	D718C	Pathogenic	0.99
LRP5	O75197-1.2	D718E	Pathogenic	0.604
LRP5	O75197-1.2	D718F	Pathogenic	0.978
LRP5	O75197-1.2	D718G	Pathogenic	0.959
LRP5	O75197-1.2	D718H	Pathogenic	0.955
LRP5	O75197-1.2	D718I	Pathogenic	0.978
LRP5	O75197-1.2	D718K	Pathogenic	0.974
LRP5	O75197-1.2	D718L	Pathogenic	0.993
LRP5	O75197-1.2	D718M	Pathogenic	0.986
LRP5	O75197-1.2	D718N	Pathogenic	0.821
LRP5	O75197-1.2	D718P	Pathogenic	0.929
LRP5	O75197-1.2	D718Q	Pathogenic	0.906
LRP5	O75197-1.2	D718R	Pathogenic	0.991
LRP5	O75197-1.2	D718S	Pathogenic	0.892
LRP5	O75197-1.2	D718T	Pathogenic	0.952
LRP5	O75197-1.2	D718V	Pathogenic	0.987
LRP5	O75197-1.2	D718W	Pathogenic	0.988
LRP5	O75197-1.2	D718Y	Pathogenic	0.989
LRP5	O75197-1.2	Y719A	Pathogenic	0.992
LRP5	O75197-1.2	Y719C	Pathogenic	0.996
LRP5	O75197-1.2	Y719D	Pathogenic	0.994
LRP5	O75197-1.2	Y719E	Pathogenic	0.983
LRP5	O75197-1.2	Y719F	Neutral	0.32
LRP5	O75197-1.2	Y719G	Pathogenic	0.997
LRP5	O75197-1.2	Y719H	Pathogenic	0.582
LRP5	O75197-1.2	Y719I	Pathogenic	0.975
LRP5	O75197-1.2	Y719K	Pathogenic	0.978
LRP5	O75197-1.2	Y719L	Pathogenic	0.977
LRP5	O75197-1.2	Y719M	Pathogenic	0.985
LRP5	O75197-1.2	Y719N	Pathogenic	0.984
LRP5	O75197-1.2	Y719P	Pathogenic	0.998
LRP5	O75197-1.2	Y719Q	Pathogenic	0.966
LRP5	O75197-1.2	Y719R	Pathogenic	0.978
LRP5	O75197-1.2	Y719S	Pathogenic	0.99
LRP5	O75197-1.2	Y719T	Pathogenic	0.992
LRP5	O75197-1.2	Y719V	Pathogenic	0.985
LRP5	O75197-1.2	Y719W	Neutral	0.48
LRP5	O75197-1.2	P720A	Pathogenic	0.997
LRP5	O75197-1.2	P720C	Pathogenic	1.0
LRP5	O75197-1.2	P720D	Pathogenic	0.992
LRP5	O75197-1.2	P720E	Pathogenic	0.992
LRP5	O75197-1.2	P720F	Pathogenic	1.0
LRP5	O75197-1.2	P720G	Pathogenic	0.999
LRP5	O75197-1.2	P720H	Pathogenic	0.999
LRP5	O75197-1.2	P720I	Pathogenic	0.999
LRP5	O75197-1.2	P720K	Pathogenic	0.989
LRP5	O75197-1.2	P720L	Pathogenic	0.999
LRP5	O75197-1.2	P720M	Pathogenic	0.999
LRP5	O75197-1.2	P720N	Pathogenic	0.998
LRP5	O75197-1.2	P720Q	Pathogenic	0.995
LRP5	O75197-1.2	P720R	Pathogenic	0.996
LRP5	O75197-1.2	P720S	Pathogenic	0.996
LRP5	O75197-1.2	P720T	Pathogenic	0.997
LRP5	O75197-1.2	P720V	Pathogenic	0.999
LRP5	O75197-1.2	P720W	Pathogenic	1.0
LRP5	O75197-1.2	P720Y	Pathogenic	1.0
LRP5	O75197-1.2	E721A	Pathogenic	0.994
LRP5	O75197-1.2	E721C	Pathogenic	1.0
LRP5	O75197-1.2	E721D	Pathogenic	0.921
LRP5	O75197-1.2	E721F	Pathogenic	0.997
LRP5	O75197-1.2	E721G	Pathogenic	0.998
LRP5	O75197-1.2	E721H	Pathogenic	0.984
LRP5	O75197-1.2	E721I	Pathogenic	0.997
LRP5	O75197-1.2	E721K	Pathogenic	0.967
LRP5	O75197-1.2	E721L	Pathogenic	0.998
LRP5	O75197-1.2	E721M	Pathogenic	0.995
LRP5	O75197-1.2	E721N	Pathogenic	0.992
LRP5	O75197-1.2	E721P	Pathogenic	0.991
LRP5	O75197-1.2	E721Q	Pathogenic	0.903
LRP5	O75197-1.2	E721R	Pathogenic	0.988
LRP5	O75197-1.2	E721S	Pathogenic	0.986
LRP5	O75197-1.2	E721T	Pathogenic	0.994
LRP5	O75197-1.2	E721V	Pathogenic	0.995
LRP5	O75197-1.2	E721W	Pathogenic	0.996
LRP5	O75197-1.2	E721Y	Pathogenic	0.996
LRP5	O75197-1.2	G722A	Pathogenic	0.985
LRP5	O75197-1.2	G722C	Pathogenic	0.999
LRP5	O75197-1.2	G722D	Pathogenic	0.992
LRP5	O75197-1.2	G722E	Pathogenic	0.998
LRP5	O75197-1.2	G722F	Pathogenic	0.998
LRP5	O75197-1.2	G722H	Pathogenic	0.998
LRP5	O75197-1.2	G722I	Pathogenic	0.999
LRP5	O75197-1.2	G722K	Pathogenic	0.997
LRP5	O75197-1.2	G722L	Pathogenic	0.999
LRP5	O75197-1.2	G722M	Pathogenic	0.999
LRP5	O75197-1.2	G722N	Pathogenic	0.979
LRP5	O75197-1.2	G722P	Pathogenic	0.997
LRP5	O75197-1.2	G722Q	Pathogenic	0.998
LRP5	O75197-1.2	G722R	Pathogenic	0.996
LRP5	O75197-1.2	G722S	Pathogenic	0.988
LRP5	O75197-1.2	G722T	Pathogenic	0.998
LRP5	O75197-1.2	G722V	Pathogenic	0.999
LRP5	O75197-1.2	G722W	Pathogenic	0.989
LRP5	O75197-1.2	G722Y	Pathogenic	0.999
LRP5	O75197-1.2	M723A	Pathogenic	0.992
LRP5	O75197-1.2	M723C	Pathogenic	0.996
LRP5	O75197-1.2	M723D	Pathogenic	0.998
LRP5	O75197-1.2	M723E	Pathogenic	0.995
LRP5	O75197-1.2	M723F	Pathogenic	0.985
LRP5	O75197-1.2	M723G	Pathogenic	0.999
LRP5	O75197-1.2	M723H	Pathogenic	0.997
LRP5	O75197-1.2	M723I	Pathogenic	0.955
LRP5	O75197-1.2	M723K	Pathogenic	0.978
LRP5	O75197-1.2	M723L	Pathogenic	0.885
LRP5	O75197-1.2	M723N	Pathogenic	0.995
LRP5	O75197-1.2	M723P	Pathogenic	0.998
LRP5	O75197-1.2	M723Q	Pathogenic	0.967
LRP5	O75197-1.2	M723R	Pathogenic	0.977
LRP5	O75197-1.2	M723S	Pathogenic	0.99
LRP5	O75197-1.2	M723T	Pathogenic	0.992
LRP5	O75197-1.2	M723V	Pathogenic	0.972
LRP5	O75197-1.2	M723W	Pathogenic	0.992
LRP5	O75197-1.2	M723Y	Pathogenic	0.996
LRP5	O75197-1.2	A724C	Pathogenic	0.987
LRP5	O75197-1.2	A724D	Pathogenic	0.998
LRP5	O75197-1.2	A724E	Pathogenic	0.994
LRP5	O75197-1.2	A724F	Pathogenic	0.997
LRP5	O75197-1.2	A724G	Pathogenic	0.99
LRP5	O75197-1.2	A724H	Pathogenic	0.999
LRP5	O75197-1.2	A724I	Pathogenic	0.99
LRP5	O75197-1.2	A724K	Pathogenic	0.992
LRP5	O75197-1.2	A724L	Pathogenic	0.991
LRP5	O75197-1.2	A724M	Pathogenic	0.994
LRP5	O75197-1.2	A724N	Pathogenic	0.998
LRP5	O75197-1.2	A724P	Pathogenic	0.996
LRP5	O75197-1.2	A724Q	Pathogenic	0.996
LRP5	O75197-1.2	A724R	Pathogenic	0.991
LRP5	O75197-1.2	A724S	Pathogenic	0.971
LRP5	O75197-1.2	A724T	Pathogenic	0.992
LRP5	O75197-1.2	A724V	Pathogenic	0.983
LRP5	O75197-1.2	A724W	Pathogenic	0.998
LRP5	O75197-1.2	A724Y	Pathogenic	0.998
LRP5	O75197-1.2	V725A	Pathogenic	0.919
LRP5	O75197-1.2	V725C	Pathogenic	0.985
LRP5	O75197-1.2	V725D	Pathogenic	0.992
LRP5	O75197-1.2	V725E	Pathogenic	0.979
LRP5	O75197-1.2	V725F	Pathogenic	0.979
LRP5	O75197-1.2	V725G	Pathogenic	0.996
LRP5	O75197-1.2	V725H	Pathogenic	0.996
LRP5	O75197-1.2	V725I	Neutral	0.356
LRP5	O75197-1.2	V725K	Pathogenic	0.971
LRP5	O75197-1.2	V725L	Pathogenic	0.849
LRP5	O75197-1.2	V725M	Pathogenic	0.895
LRP5	O75197-1.2	V725N	Pathogenic	0.993
LRP5	O75197-1.2	V725P	Pathogenic	0.994
LRP5	O75197-1.2	V725Q	Pathogenic	0.986
LRP5	O75197-1.2	V725R	Pathogenic	0.99
LRP5	O75197-1.2	V725S	Pathogenic	0.987
LRP5	O75197-1.2	V725T	Pathogenic	0.918
LRP5	O75197-1.2	V725W	Pathogenic	0.996
LRP5	O75197-1.2	V725Y	Pathogenic	0.984
LRP5	O75197-1.2	D726A	Pathogenic	0.997
LRP5	O75197-1.2	D726C	Pathogenic	0.998
LRP5	O75197-1.2	D726E	Pathogenic	0.907
LRP5	O75197-1.2	D726F	Pathogenic	0.996
LRP5	O75197-1.2	D726G	Pathogenic	0.993
LRP5	O75197-1.2	D726H	Pathogenic	0.993
LRP5	O75197-1.2	D726I	Pathogenic	0.996
LRP5	O75197-1.2	D726K	Pathogenic	0.996
LRP5	O75197-1.2	D726L	Pathogenic	0.999
LRP5	O75197-1.2	D726M	Pathogenic	0.998
LRP5	O75197-1.2	D726N	Pathogenic	0.967
LRP5	O75197-1.2	D726P	Pathogenic	0.988
LRP5	O75197-1.2	D726Q	Pathogenic	0.984
LRP5	O75197-1.2	D726R	Pathogenic	0.999
LRP5	O75197-1.2	D726S	Pathogenic	0.981
LRP5	O75197-1.2	D726T	Pathogenic	0.992
LRP5	O75197-1.2	D726V	Pathogenic	0.998
LRP5	O75197-1.2	D726W	Pathogenic	0.998
LRP5	O75197-1.2	D726Y	Pathogenic	0.998
LRP5	O75197-1.2	W727A	Pathogenic	1.0
LRP5	O75197-1.2	W727C	Pathogenic	0.999
LRP5	O75197-1.2	W727D	Pathogenic	1.0
LRP5	O75197-1.2	W727E	Pathogenic	0.999
LRP5	O75197-1.2	W727F	Pathogenic	0.991
LRP5	O75197-1.2	W727G	Pathogenic	0.998
LRP5	O75197-1.2	W727H	Pathogenic	0.999
LRP5	O75197-1.2	W727I	Pathogenic	1.0
LRP5	O75197-1.2	W727K	Pathogenic	0.999
LRP5	O75197-1.2	W727L	Pathogenic	1.0
LRP5	O75197-1.2	W727M	Pathogenic	0.998
LRP5	O75197-1.2	W727N	Pathogenic	1.0
LRP5	O75197-1.2	W727P	Pathogenic	1.0
LRP5	O75197-1.2	W727Q	Pathogenic	0.998
LRP5	O75197-1.2	W727R	Pathogenic	0.999
LRP5	O75197-1.2	W727S	Pathogenic	0.999
LRP5	O75197-1.2	W727T	Pathogenic	0.999
LRP5	O75197-1.2	W727V	Pathogenic	1.0
LRP5	O75197-1.2	W727Y	Pathogenic	0.945
LRP5	O75197-1.2	M728A	Pathogenic	0.563
LRP5	O75197-1.2	M728C	Pathogenic	0.708
LRP5	O75197-1.2	M728D	Pathogenic	0.825
LRP5	O75197-1.2	M728E	Pathogenic	0.643
LRP5	O75197-1.2	M728F	Neutral	0.387
LRP5	O75197-1.2	M728G	Pathogenic	0.898
LRP5	O75197-1.2	M728H	Pathogenic	0.784
LRP5	O75197-1.2	M728I	Neutral	0.173
LRP5	O75197-1.2	M728K	Neutral	0.303
LRP5	O75197-1.2	M728L	Neutral	0.07
LRP5	O75197-1.2	M728N	Pathogenic	0.645
LRP5	O75197-1.2	M728P	Pathogenic	0.854
LRP5	O75197-1.2	M728Q	Neutral	0.222
LRP5	O75197-1.2	M728R	Neutral	0.296
LRP5	O75197-1.2	M728S	Neutral	0.489
LRP5	O75197-1.2	M728T	Pathogenic	0.562
LRP5	O75197-1.2	M728V	Neutral	0.25
LRP5	O75197-1.2	M728W	Pathogenic	0.549
LRP5	O75197-1.2	M728Y	Pathogenic	0.711
LRP5	O75197-1.2	G729A	Pathogenic	0.915
LRP5	O75197-1.2	G729C	Pathogenic	0.994
LRP5	O75197-1.2	G729D	Pathogenic	0.954
LRP5	O75197-1.2	G729E	Pathogenic	0.986
LRP5	O75197-1.2	G729F	Pathogenic	0.986
LRP5	O75197-1.2	G729H	Pathogenic	0.991
LRP5	O75197-1.2	G729I	Pathogenic	0.995
LRP5	O75197-1.2	G729K	Pathogenic	0.98
LRP5	O75197-1.2	G729L	Pathogenic	0.996
LRP5	O75197-1.2	G729M	Pathogenic	0.992
LRP5	O75197-1.2	G729N	Pathogenic	0.888
LRP5	O75197-1.2	G729P	Pathogenic	0.985
LRP5	O75197-1.2	G729Q	Pathogenic	0.99
LRP5	O75197-1.2	G729R	Pathogenic	0.979
LRP5	O75197-1.2	G729S	Pathogenic	0.931
LRP5	O75197-1.2	G729T	Pathogenic	0.99
LRP5	O75197-1.2	G729V	Pathogenic	0.992
LRP5	O75197-1.2	G729W	Pathogenic	0.938
LRP5	O75197-1.2	G729Y	Pathogenic	0.993
LRP5	O75197-1.2	K730A	Pathogenic	0.835
LRP5	O75197-1.2	K730C	Pathogenic	0.964
LRP5	O75197-1.2	K730D	Pathogenic	0.932
LRP5	O75197-1.2	K730E	Pathogenic	0.577
LRP5	O75197-1.2	K730F	Pathogenic	0.933
LRP5	O75197-1.2	K730G	Pathogenic	0.952
LRP5	O75197-1.2	K730H	Pathogenic	0.866
LRP5	O75197-1.2	K730I	Pathogenic	0.931
LRP5	O75197-1.2	K730L	Pathogenic	0.829
LRP5	O75197-1.2	K730M	Pathogenic	0.709
LRP5	O75197-1.2	K730N	Pathogenic	0.797
LRP5	O75197-1.2	K730P	Pathogenic	0.785
LRP5	O75197-1.2	K730Q	Neutral	0.486
LRP5	O75197-1.2	K730R	Neutral	0.383
LRP5	O75197-1.2	K730S	Pathogenic	0.696
LRP5	O75197-1.2	K730T	Pathogenic	0.847
LRP5	O75197-1.2	K730V	Pathogenic	0.879
LRP5	O75197-1.2	K730W	Pathogenic	0.898
LRP5	O75197-1.2	K730Y	Pathogenic	0.905
LRP5	O75197-1.2	N731A	Pathogenic	0.999
LRP5	O75197-1.2	N731C	Pathogenic	0.999
LRP5	O75197-1.2	N731D	Pathogenic	0.984
LRP5	O75197-1.2	N731E	Pathogenic	0.995
LRP5	O75197-1.2	N731F	Pathogenic	0.999
LRP5	O75197-1.2	N731G	Pathogenic	0.992
LRP5	O75197-1.2	N731H	Pathogenic	0.974
LRP5	O75197-1.2	N731I	Pathogenic	0.999
LRP5	O75197-1.2	N731K	Pathogenic	0.993
LRP5	O75197-1.2	N731L	Pathogenic	0.999
LRP5	O75197-1.2	N731M	Pathogenic	0.997
LRP5	O75197-1.2	N731P	Pathogenic	0.998
LRP5	O75197-1.2	N731Q	Pathogenic	0.994
LRP5	O75197-1.2	N731R	Pathogenic	0.993
LRP5	O75197-1.2	N731S	Pathogenic	0.977
LRP5	O75197-1.2	N731T	Pathogenic	0.99
LRP5	O75197-1.2	N731V	Pathogenic	0.999
LRP5	O75197-1.2	N731W	Pathogenic	0.999
LRP5	O75197-1.2	N731Y	Pathogenic	0.998
LRP5	O75197-1.2	L732A	Pathogenic	0.824
LRP5	O75197-1.2	L732C	Pathogenic	0.898
LRP5	O75197-1.2	L732D	Pathogenic	0.981
LRP5	O75197-1.2	L732E	Pathogenic	0.952
LRP5	O75197-1.2	L732F	Pathogenic	0.842
LRP5	O75197-1.2	L732G	Pathogenic	0.99
LRP5	O75197-1.2	L732H	Pathogenic	0.976
LRP5	O75197-1.2	L732I	Neutral	0.366
LRP5	O75197-1.2	L732K	Pathogenic	0.827
LRP5	O75197-1.2	L732M	Neutral	0.294
LRP5	O75197-1.2	L732N	Pathogenic	0.953
LRP5	O75197-1.2	L732P	Pathogenic	0.985
LRP5	O75197-1.2	L732Q	Pathogenic	0.905
LRP5	O75197-1.2	L732R	Pathogenic	0.823
LRP5	O75197-1.2	L732S	Pathogenic	0.913
LRP5	O75197-1.2	L732T	Pathogenic	0.823
LRP5	O75197-1.2	L732V	Pathogenic	0.548
LRP5	O75197-1.2	L732W	Pathogenic	0.969
LRP5	O75197-1.2	L732Y	Pathogenic	0.899
LRP5	O75197-1.2	Y733A	Pathogenic	0.999
LRP5	O75197-1.2	Y733C	Pathogenic	1.0
LRP5	O75197-1.2	Y733D	Pathogenic	0.999
LRP5	O75197-1.2	Y733E	Pathogenic	0.998
LRP5	O75197-1.2	Y733F	Pathogenic	0.804
LRP5	O75197-1.2	Y733G	Pathogenic	1.0
LRP5	O75197-1.2	Y733H	Pathogenic	0.924
LRP5	O75197-1.2	Y733I	Pathogenic	0.997
LRP5	O75197-1.2	Y733K	Pathogenic	0.997
LRP5	O75197-1.2	Y733L	Pathogenic	0.997
LRP5	O75197-1.2	Y733M	Pathogenic	0.998
LRP5	O75197-1.2	Y733N	Pathogenic	0.998
LRP5	O75197-1.2	Y733P	Pathogenic	1.0
LRP5	O75197-1.2	Y733Q	Pathogenic	0.996
LRP5	O75197-1.2	Y733R	Pathogenic	0.997
LRP5	O75197-1.2	Y733S	Pathogenic	0.999
LRP5	O75197-1.2	Y733T	Pathogenic	0.999
LRP5	O75197-1.2	Y733V	Pathogenic	0.998
LRP5	O75197-1.2	Y733W	Pathogenic	0.89
LRP5	O75197-1.2	W734A	Pathogenic	1.0
LRP5	O75197-1.2	W734C	Pathogenic	0.999
LRP5	O75197-1.2	W734D	Pathogenic	1.0
LRP5	O75197-1.2	W734E	Pathogenic	0.999
LRP5	O75197-1.2	W734F	Pathogenic	0.991
LRP5	O75197-1.2	W734G	Pathogenic	0.998
LRP5	O75197-1.2	W734H	Pathogenic	0.999
LRP5	O75197-1.2	W734I	Pathogenic	1.0
LRP5	O75197-1.2	W734K	Pathogenic	0.999
LRP5	O75197-1.2	W734L	Pathogenic	1.0
LRP5	O75197-1.2	W734M	Pathogenic	0.998
LRP5	O75197-1.2	W734N	Pathogenic	1.0
LRP5	O75197-1.2	W734P	Pathogenic	1.0
LRP5	O75197-1.2	W734Q	Pathogenic	0.998
LRP5	O75197-1.2	W734R	Pathogenic	0.999
LRP5	O75197-1.2	W734S	Pathogenic	0.999
LRP5	O75197-1.2	W734T	Pathogenic	0.999
LRP5	O75197-1.2	W734V	Pathogenic	1.0
LRP5	O75197-1.2	W734Y	Pathogenic	0.945
LRP5	O75197-1.2	A735C	Pathogenic	0.922
LRP5	O75197-1.2	A735D	Pathogenic	0.987
LRP5	O75197-1.2	A735E	Pathogenic	0.965
LRP5	O75197-1.2	A735F	Pathogenic	0.98
LRP5	O75197-1.2	A735G	Pathogenic	0.943
LRP5	O75197-1.2	A735H	Pathogenic	0.994
LRP5	O75197-1.2	A735I	Pathogenic	0.942
LRP5	O75197-1.2	A735K	Pathogenic	0.95
LRP5	O75197-1.2	A735L	Pathogenic	0.947
LRP5	O75197-1.2	A735M	Pathogenic	0.965
LRP5	O75197-1.2	A735N	Pathogenic	0.989
LRP5	O75197-1.2	A735P	Pathogenic	0.979
LRP5	O75197-1.2	A735Q	Pathogenic	0.975
LRP5	O75197-1.2	A735R	Pathogenic	0.949
LRP5	O75197-1.2	A735S	Pathogenic	0.843
LRP5	O75197-1.2	A735T	Pathogenic	0.954
LRP5	O75197-1.2	A735V	Pathogenic	0.903
LRP5	O75197-1.2	A735W	Pathogenic	0.99
LRP5	O75197-1.2	A735Y	Pathogenic	0.99
LRP5	O75197-1.2	D736A	Pathogenic	0.997
LRP5	O75197-1.2	D736C	Pathogenic	0.998
LRP5	O75197-1.2	D736E	Pathogenic	0.907
LRP5	O75197-1.2	D736F	Pathogenic	0.996
LRP5	O75197-1.2	D736G	Pathogenic	0.993
LRP5	O75197-1.2	D736H	Pathogenic	0.993
LRP5	O75197-1.2	D736I	Pathogenic	0.996
LRP5	O75197-1.2	D736K	Pathogenic	0.996
LRP5	O75197-1.2	D736L	Pathogenic	0.999
LRP5	O75197-1.2	D736M	Pathogenic	0.998
LRP5	O75197-1.2	D736N	Pathogenic	0.967
LRP5	O75197-1.2	D736P	Pathogenic	0.988
LRP5	O75197-1.2	D736Q	Pathogenic	0.984
LRP5	O75197-1.2	D736R	Pathogenic	0.999
LRP5	O75197-1.2	D736S	Pathogenic	0.981
LRP5	O75197-1.2	D736T	Pathogenic	0.992
LRP5	O75197-1.2	D736V	Pathogenic	0.998
LRP5	O75197-1.2	D736W	Pathogenic	0.998
LRP5	O75197-1.2	D736Y	Pathogenic	0.998
LRP5	O75197-1.2	T737A	Pathogenic	0.958
LRP5	O75197-1.2	T737C	Pathogenic	0.975
LRP5	O75197-1.2	T737D	Pathogenic	0.968
LRP5	O75197-1.2	T737E	Pathogenic	0.97
LRP5	O75197-1.2	T737F	Pathogenic	0.982
LRP5	O75197-1.2	T737G	Pathogenic	0.994
LRP5	O75197-1.2	T737H	Pathogenic	0.995
LRP5	O75197-1.2	T737I	Pathogenic	0.947
LRP5	O75197-1.2	T737K	Pathogenic	0.958
LRP5	O75197-1.2	T737L	Pathogenic	0.951
LRP5	O75197-1.2	T737M	Pathogenic	0.967
LRP5	O75197-1.2	T737N	Pathogenic	0.919
LRP5	O75197-1.2	T737P	Pathogenic	0.98
LRP5	O75197-1.2	T737Q	Pathogenic	0.979
LRP5	O75197-1.2	T737R	Pathogenic	0.957
LRP5	O75197-1.2	T737S	Pathogenic	0.858
LRP5	O75197-1.2	T737V	Pathogenic	0.911
LRP5	O75197-1.2	T737W	Pathogenic	0.972
LRP5	O75197-1.2	T737Y	Pathogenic	0.991
LRP5	O75197-1.2	G738A	Pathogenic	0.936
LRP5	O75197-1.2	G738C	Pathogenic	0.995
LRP5	O75197-1.2	G738D	Pathogenic	0.966
LRP5	O75197-1.2	G738E	Pathogenic	0.99
LRP5	O75197-1.2	G738F	Pathogenic	0.99
LRP5	O75197-1.2	G738H	Pathogenic	0.993
LRP5	O75197-1.2	G738I	Pathogenic	0.997
LRP5	O75197-1.2	G738K	Pathogenic	0.985
LRP5	O75197-1.2	G738L	Pathogenic	0.997
LRP5	O75197-1.2	G738M	Pathogenic	0.994
LRP5	O75197-1.2	G738N	Pathogenic	0.915
LRP5	O75197-1.2	G738P	Pathogenic	0.989
LRP5	O75197-1.2	G738Q	Pathogenic	0.993
LRP5	O75197-1.2	G738R	Pathogenic	0.985
LRP5	O75197-1.2	G738S	Pathogenic	0.949
LRP5	O75197-1.2	G738T	Pathogenic	0.993
LRP5	O75197-1.2	G738V	Pathogenic	0.994
LRP5	O75197-1.2	G738W	Pathogenic	0.954
LRP5	O75197-1.2	G738Y	Pathogenic	0.995
LRP5	O75197-1.2	T739A	Pathogenic	0.95
LRP5	O75197-1.2	T739C	Pathogenic	0.971
LRP5	O75197-1.2	T739D	Pathogenic	0.962
LRP5	O75197-1.2	T739E	Pathogenic	0.965
LRP5	O75197-1.2	T739F	Pathogenic	0.979
LRP5	O75197-1.2	T739G	Pathogenic	0.993
LRP5	O75197-1.2	T739H	Pathogenic	0.994
LRP5	O75197-1.2	T739I	Pathogenic	0.938
LRP5	O75197-1.2	T739K	Pathogenic	0.951
LRP5	O75197-1.2	T739L	Pathogenic	0.943
LRP5	O75197-1.2	T739M	Pathogenic	0.962
LRP5	O75197-1.2	T739N	Pathogenic	0.906
LRP5	O75197-1.2	T739P	Pathogenic	0.977
LRP5	O75197-1.2	T739Q	Pathogenic	0.976
LRP5	O75197-1.2	T739R	Pathogenic	0.95
LRP5	O75197-1.2	T739S	Pathogenic	0.837
LRP5	O75197-1.2	T739V	Pathogenic	0.897
LRP5	O75197-1.2	T739W	Pathogenic	0.967
LRP5	O75197-1.2	T739Y	Pathogenic	0.99
LRP5	O75197-1.2	N740A	Pathogenic	0.986
LRP5	O75197-1.2	N740C	Pathogenic	0.992
LRP5	O75197-1.2	N740D	Pathogenic	0.839
LRP5	O75197-1.2	N740E	Pathogenic	0.946
LRP5	O75197-1.2	N740F	Pathogenic	0.983
LRP5	O75197-1.2	N740G	Pathogenic	0.909
LRP5	O75197-1.2	N740H	Pathogenic	0.754
LRP5	O75197-1.2	N740I	Pathogenic	0.983
LRP5	O75197-1.2	N740K	Pathogenic	0.925
LRP5	O75197-1.2	N740L	Pathogenic	0.985
LRP5	O75197-1.2	N740M	Pathogenic	0.97
LRP5	O75197-1.2	N740P	Pathogenic	0.981
LRP5	O75197-1.2	N740Q	Pathogenic	0.928
LRP5	O75197-1.2	N740R	Pathogenic	0.923
LRP5	O75197-1.2	N740S	Pathogenic	0.78
LRP5	O75197-1.2	N740T	Pathogenic	0.896
LRP5	O75197-1.2	N740V	Pathogenic	0.99
LRP5	O75197-1.2	N740W	Pathogenic	0.991
LRP5	O75197-1.2	N740Y	Pathogenic	0.975
LRP5	O75197-1.2	R741A	Pathogenic	0.986
LRP5	O75197-1.2	R741C	Pathogenic	0.997
LRP5	O75197-1.2	R741D	Pathogenic	0.998
LRP5	O75197-1.2	R741E	Pathogenic	0.983
LRP5	O75197-1.2	R741F	Pathogenic	0.995
LRP5	O75197-1.2	R741G	Pathogenic	0.996
LRP5	O75197-1.2	R741H	Pathogenic	0.968
LRP5	O75197-1.2	R741I	Pathogenic	0.995
LRP5	O75197-1.2	R741K	Pathogenic	0.901
LRP5	O75197-1.2	R741L	Pathogenic	0.986
LRP5	O75197-1.2	R741M	Pathogenic	0.972
LRP5	O75197-1.2	R741N	Pathogenic	0.982
LRP5	O75197-1.2	R741P	Pathogenic	0.994
LRP5	O75197-1.2	R741Q	Pathogenic	0.931
LRP5	O75197-1.2	R741S	Pathogenic	0.99
LRP5	O75197-1.2	R741T	Pathogenic	0.987
LRP5	O75197-1.2	R741V	Pathogenic	0.997
LRP5	O75197-1.2	R741W	Pathogenic	0.992
LRP5	O75197-1.2	R741Y	Pathogenic	0.993
LRP5	O75197-1.2	I742A	Pathogenic	0.986
LRP5	O75197-1.2	I742C	Pathogenic	0.993
LRP5	O75197-1.2	I742D	Pathogenic	0.996
LRP5	O75197-1.2	I742E	Pathogenic	0.997
LRP5	O75197-1.2	I742F	Pathogenic	0.989
LRP5	O75197-1.2	I742G	Pathogenic	0.999
LRP5	O75197-1.2	I742H	Pathogenic	0.998
LRP5	O75197-1.2	I742K	Pathogenic	0.995
LRP5	O75197-1.2	I742L	Pathogenic	0.905
LRP5	O75197-1.2	I742M	Pathogenic	0.95
LRP5	O75197-1.2	I742N	Pathogenic	0.997
LRP5	O75197-1.2	I742P	Pathogenic	0.999
LRP5	O75197-1.2	I742Q	Pathogenic	0.998
LRP5	O75197-1.2	I742R	Pathogenic	0.995
LRP5	O75197-1.2	I742S	Pathogenic	0.994
LRP5	O75197-1.2	I742T	Pathogenic	0.986
LRP5	O75197-1.2	I742V	Pathogenic	0.663
LRP5	O75197-1.2	I742W	Pathogenic	0.999
LRP5	O75197-1.2	I742Y	Pathogenic	0.993
LRP5	O75197-1.2	E743A	Pathogenic	0.996
LRP5	O75197-1.2	E743C	Pathogenic	1.0
LRP5	O75197-1.2	E743D	Pathogenic	0.947
LRP5	O75197-1.2	E743F	Pathogenic	0.998
LRP5	O75197-1.2	E743G	Pathogenic	0.999
LRP5	O75197-1.2	E743H	Pathogenic	0.989
LRP5	O75197-1.2	E743I	Pathogenic	0.998
LRP5	O75197-1.2	E743K	Pathogenic	0.978
LRP5	O75197-1.2	E743L	Pathogenic	0.998
LRP5	O75197-1.2	E743M	Pathogenic	0.997
LRP5	O75197-1.2	E743N	Pathogenic	0.994
LRP5	O75197-1.2	E743P	Pathogenic	0.994
LRP5	O75197-1.2	E743Q	Pathogenic	0.933
LRP5	O75197-1.2	E743R	Pathogenic	0.992
LRP5	O75197-1.2	E743S	Pathogenic	0.991
LRP5	O75197-1.2	E743T	Pathogenic	0.996
LRP5	O75197-1.2	E743V	Pathogenic	0.997
LRP5	O75197-1.2	E743W	Pathogenic	0.997
LRP5	O75197-1.2	E743Y	Pathogenic	0.998
LRP5	O75197-1.2	V744A	Pathogenic	0.939
LRP5	O75197-1.2	V744C	Pathogenic	0.989
LRP5	O75197-1.2	V744D	Pathogenic	0.994
LRP5	O75197-1.2	V744E	Pathogenic	0.985
LRP5	O75197-1.2	V744F	Pathogenic	0.985
LRP5	O75197-1.2	V744G	Pathogenic	0.997
LRP5	O75197-1.2	V744H	Pathogenic	0.997
LRP5	O75197-1.2	V744I	Neutral	0.428
LRP5	O75197-1.2	V744K	Pathogenic	0.978
LRP5	O75197-1.2	V744L	Pathogenic	0.884
LRP5	O75197-1.2	V744M	Pathogenic	0.92
LRP5	O75197-1.2	V744N	Pathogenic	0.995
LRP5	O75197-1.2	V744P	Pathogenic	0.995
LRP5	O75197-1.2	V744Q	Pathogenic	0.989
LRP5	O75197-1.2	V744R	Pathogenic	0.993
LRP5	O75197-1.2	V744S	Pathogenic	0.991
LRP5	O75197-1.2	V744T	Pathogenic	0.939
LRP5	O75197-1.2	V744W	Pathogenic	0.997
LRP5	O75197-1.2	V744Y	Pathogenic	0.988
LRP5	O75197-1.2	A745C	Neutral	0.406
LRP5	O75197-1.2	A745D	Pathogenic	0.814
LRP5	O75197-1.2	A745E	Pathogenic	0.611
LRP5	O75197-1.2	A745F	Pathogenic	0.739
LRP5	O75197-1.2	A745G	Neutral	0.486
LRP5	O75197-1.2	A745H	Pathogenic	0.904
LRP5	O75197-1.2	A745I	Neutral	0.484
LRP5	O75197-1.2	A745K	Pathogenic	0.524
LRP5	O75197-1.2	A745L	Pathogenic	0.507
LRP5	O75197-1.2	A745M	Pathogenic	0.61
LRP5	O75197-1.2	A745N	Pathogenic	0.834
LRP5	O75197-1.2	A745P	Pathogenic	0.723
LRP5	O75197-1.2	A745Q	Pathogenic	0.693
LRP5	O75197-1.2	A745R	Pathogenic	0.515
LRP5	O75197-1.2	A745S	Neutral	0.235
LRP5	O75197-1.2	A745T	Pathogenic	0.541
LRP5	O75197-1.2	A745V	Neutral	0.349
LRP5	O75197-1.2	A745W	Pathogenic	0.845
LRP5	O75197-1.2	A745Y	Pathogenic	0.855
LRP5	O75197-1.2	R746A	Pathogenic	0.701
LRP5	O75197-1.2	R746C	Pathogenic	0.924
LRP5	O75197-1.2	R746D	Pathogenic	0.951
LRP5	O75197-1.2	R746E	Pathogenic	0.658
LRP5	O75197-1.2	R746F	Pathogenic	0.865
LRP5	O75197-1.2	R746G	Pathogenic	0.901
LRP5	O75197-1.2	R746H	Neutral	0.495
LRP5	O75197-1.2	R746I	Pathogenic	0.862
LRP5	O75197-1.2	R746K	Neutral	0.229
LRP5	O75197-1.2	R746L	Pathogenic	0.692
LRP5	O75197-1.2	R746M	Pathogenic	0.529
LRP5	O75197-1.2	R746N	Pathogenic	0.645
LRP5	O75197-1.2	R746P	Pathogenic	0.837
LRP5	O75197-1.2	R746Q	Neutral	0.305
LRP5	O75197-1.2	R746S	Pathogenic	0.763
LRP5	O75197-1.2	R746T	Pathogenic	0.719
LRP5	O75197-1.2	R746V	Pathogenic	0.911
LRP5	O75197-1.2	R746W	Pathogenic	0.809
LRP5	O75197-1.2	R746Y	Pathogenic	0.818
LRP5	O75197-1.2	L747A	Pathogenic	0.971
LRP5	O75197-1.2	L747C	Pathogenic	0.984
LRP5	O75197-1.2	L747D	Pathogenic	0.997
LRP5	O75197-1.2	L747E	Pathogenic	0.993
LRP5	O75197-1.2	L747F	Pathogenic	0.974
LRP5	O75197-1.2	L747G	Pathogenic	0.999
LRP5	O75197-1.2	L747H	Pathogenic	0.996
LRP5	O75197-1.2	L747I	Pathogenic	0.803
LRP5	O75197-1.2	L747K	Pathogenic	0.971
LRP5	O75197-1.2	L747M	Pathogenic	0.746
LRP5	O75197-1.2	L747N	Pathogenic	0.993
LRP5	O75197-1.2	L747P	Pathogenic	0.998
LRP5	O75197-1.2	L747Q	Pathogenic	0.985
LRP5	O75197-1.2	L747R	Pathogenic	0.97
LRP5	O75197-1.2	L747S	Pathogenic	0.987
LRP5	O75197-1.2	L747T	Pathogenic	0.971
LRP5	O75197-1.2	L747V	Pathogenic	0.896
LRP5	O75197-1.2	L747W	Pathogenic	0.995
LRP5	O75197-1.2	L747Y	Pathogenic	0.984
LRP5	O75197-1.2	D748A	Pathogenic	0.987
LRP5	O75197-1.2	D748C	Pathogenic	0.992
LRP5	O75197-1.2	D748E	Pathogenic	0.676
LRP5	O75197-1.2	D748F	Pathogenic	0.983
LRP5	O75197-1.2	D748G	Pathogenic	0.97
LRP5	O75197-1.2	D748H	Pathogenic	0.967
LRP5	O75197-1.2	D748I	Pathogenic	0.984
LRP5	O75197-1.2	D748K	Pathogenic	0.981
LRP5	O75197-1.2	D748L	Pathogenic	0.995
LRP5	O75197-1.2	D748M	Pathogenic	0.99
LRP5	O75197-1.2	D748N	Pathogenic	0.863
LRP5	O75197-1.2	D748P	Pathogenic	0.947
LRP5	O75197-1.2	D748Q	Pathogenic	0.93
LRP5	O75197-1.2	D748R	Pathogenic	0.994
LRP5	O75197-1.2	D748S	Pathogenic	0.919
LRP5	O75197-1.2	D748T	Pathogenic	0.964
LRP5	O75197-1.2	D748V	Pathogenic	0.991
LRP5	O75197-1.2	D748W	Pathogenic	0.991
LRP5	O75197-1.2	D748Y	Pathogenic	0.992
LRP5	O75197-1.2	G749A	Pathogenic	0.985
LRP5	O75197-1.2	G749C	Pathogenic	0.999
LRP5	O75197-1.2	G749D	Pathogenic	0.992
LRP5	O75197-1.2	G749E	Pathogenic	0.998
LRP5	O75197-1.2	G749F	Pathogenic	0.998
LRP5	O75197-1.2	G749H	Pathogenic	0.999
LRP5	O75197-1.2	G749I	Pathogenic	0.999
LRP5	O75197-1.2	G749K	Pathogenic	0.997
LRP5	O75197-1.2	G749L	Pathogenic	0.999
LRP5	O75197-1.2	G749M	Pathogenic	0.999
LRP5	O75197-1.2	G749N	Pathogenic	0.98
LRP5	O75197-1.2	G749P	Pathogenic	0.998
LRP5	O75197-1.2	G749Q	Pathogenic	0.998
LRP5	O75197-1.2	G749R	Pathogenic	0.997
LRP5	O75197-1.2	G749S	Pathogenic	0.988
LRP5	O75197-1.2	G749T	Pathogenic	0.998
LRP5	O75197-1.2	G749V	Pathogenic	0.999
LRP5	O75197-1.2	G749W	Pathogenic	0.989
LRP5	O75197-1.2	G749Y	Pathogenic	0.999
LRP5	O75197-1.2	Q750A	Pathogenic	0.922
LRP5	O75197-1.2	Q750C	Pathogenic	0.984
LRP5	O75197-1.2	Q750D	Pathogenic	0.799
LRP5	O75197-1.2	Q750E	Neutral	0.332
LRP5	O75197-1.2	Q750F	Pathogenic	0.968
LRP5	O75197-1.2	Q750G	Pathogenic	0.979
LRP5	O75197-1.2	Q750H	Pathogenic	0.83
LRP5	O75197-1.2	Q750I	Pathogenic	0.968
LRP5	O75197-1.2	Q750K	Pathogenic	0.518
LRP5	O75197-1.2	Q750L	Pathogenic	0.917
LRP5	O75197-1.2	Q750M	Pathogenic	0.644
LRP5	O75197-1.2	Q750N	Pathogenic	0.823
LRP5	O75197-1.2	Q750P	Pathogenic	0.895
LRP5	O75197-1.2	Q750R	Pathogenic	0.51
LRP5	O75197-1.2	Q750S	Pathogenic	0.843
LRP5	O75197-1.2	Q750T	Pathogenic	0.928
LRP5	O75197-1.2	Q750V	Pathogenic	0.944
LRP5	O75197-1.2	Q750W	Pathogenic	0.863
LRP5	O75197-1.2	Q750Y	Pathogenic	0.872
LRP5	O75197-1.2	F751A	Neutral	0.209
LRP5	O75197-1.2	F751C	Neutral	0.333
LRP5	O75197-1.2	F751D	Neutral	0.242
LRP5	O75197-1.2	F751E	Neutral	0.27
LRP5	O75197-1.2	F751G	Neutral	0.372
LRP5	O75197-1.2	F751H	Neutral	0.075
LRP5	O75197-1.2	F751I	Neutral	0.104
LRP5	O75197-1.2	F751K	Neutral	0.219
LRP5	O75197-1.2	F751L	Neutral	0.098
LRP5	O75197-1.2	F751M	Neutral	0.067
LRP5	O75197-1.2	F751N	Neutral	0.272
LRP5	O75197-1.2	F751P	Pathogenic	0.786
LRP5	O75197-1.2	F751Q	Neutral	0.351
LRP5	O75197-1.2	F751R	Neutral	0.214
LRP5	O75197-1.2	F751S	Neutral	0.164
LRP5	O75197-1.2	F751T	Neutral	0.208
LRP5	O75197-1.2	F751V	Neutral	0.172
LRP5	O75197-1.2	F751W	Neutral	0.024
LRP5	O75197-1.2	F751Y	Neutral	0.002
LRP5	O75197-1.2	R752A	Pathogenic	0.989
LRP5	O75197-1.2	R752C	Pathogenic	0.998
LRP5	O75197-1.2	R752D	Pathogenic	0.999
LRP5	O75197-1.2	R752E	Pathogenic	0.986
LRP5	O75197-1.2	R752F	Pathogenic	0.996
LRP5	O75197-1.2	R752G	Pathogenic	0.997
LRP5	O75197-1.2	R752H	Pathogenic	0.974
LRP5	O75197-1.2	R752I	Pathogenic	0.996
LRP5	O75197-1.2	R752K	Pathogenic	0.918
LRP5	O75197-1.2	R752L	Pathogenic	0.988
LRP5	O75197-1.2	R752M	Pathogenic	0.977
LRP5	O75197-1.2	R752N	Pathogenic	0.986
LRP5	O75197-1.2	R752P	Pathogenic	0.995
LRP5	O75197-1.2	R752Q	Pathogenic	0.943
LRP5	O75197-1.2	R752S	Pathogenic	0.992
LRP5	O75197-1.2	R752T	Pathogenic	0.99
LRP5	O75197-1.2	R752V	Pathogenic	0.997
LRP5	O75197-1.2	R752W	Pathogenic	0.994
LRP5	O75197-1.2	R752Y	Pathogenic	0.994
LRP5	O75197-1.2	Q753A	Pathogenic	0.967
LRP5	O75197-1.2	Q753C	Pathogenic	0.994
LRP5	O75197-1.2	Q753D	Pathogenic	0.908
LRP5	O75197-1.2	Q753E	Pathogenic	0.553
LRP5	O75197-1.2	Q753F	Pathogenic	0.987
LRP5	O75197-1.2	Q753G	Pathogenic	0.991
LRP5	O75197-1.2	Q753H	Pathogenic	0.924
LRP5	O75197-1.2	Q753I	Pathogenic	0.987
LRP5	O75197-1.2	Q753K	Pathogenic	0.728
LRP5	O75197-1.2	Q753L	Pathogenic	0.965
LRP5	O75197-1.2	Q753M	Pathogenic	0.819
LRP5	O75197-1.2	Q753N	Pathogenic	0.921
LRP5	O75197-1.2	Q753P	Pathogenic	0.955
LRP5	O75197-1.2	Q753R	Pathogenic	0.721
LRP5	O75197-1.2	Q753S	Pathogenic	0.93
LRP5	O75197-1.2	Q753T	Pathogenic	0.97
LRP5	O75197-1.2	Q753V	Pathogenic	0.977
LRP5	O75197-1.2	Q753W	Pathogenic	0.94
LRP5	O75197-1.2	Q753Y	Pathogenic	0.944
LRP5	O75197-1.2	V754A	Pathogenic	0.946
LRP5	O75197-1.2	V754C	Pathogenic	0.99
LRP5	O75197-1.2	V754D	Pathogenic	0.995
LRP5	O75197-1.2	V754E	Pathogenic	0.986
LRP5	O75197-1.2	V754F	Pathogenic	0.986
LRP5	O75197-1.2	V754G	Pathogenic	0.997
LRP5	O75197-1.2	V754H	Pathogenic	0.998
LRP5	O75197-1.2	V754I	Neutral	0.459
LRP5	O75197-1.2	V754K	Pathogenic	0.981
LRP5	O75197-1.2	V754L	Pathogenic	0.896
LRP5	O75197-1.2	V754M	Pathogenic	0.929
LRP5	O75197-1.2	V754N	Pathogenic	0.996
LRP5	O75197-1.2	V754P	Pathogenic	0.996
LRP5	O75197-1.2	V754Q	Pathogenic	0.991
LRP5	O75197-1.2	V754R	Pathogenic	0.993
LRP5	O75197-1.2	V754S	Pathogenic	0.992
LRP5	O75197-1.2	V754T	Pathogenic	0.945
LRP5	O75197-1.2	V754W	Pathogenic	0.998
LRP5	O75197-1.2	V754Y	Pathogenic	0.99
LRP5	O75197-1.2	L755A	Pathogenic	0.971
LRP5	O75197-1.2	L755C	Pathogenic	0.984
LRP5	O75197-1.2	L755D	Pathogenic	0.997
LRP5	O75197-1.2	L755E	Pathogenic	0.993
LRP5	O75197-1.2	L755F	Pathogenic	0.975
LRP5	O75197-1.2	L755G	Pathogenic	0.999
LRP5	O75197-1.2	L755H	Pathogenic	0.997
LRP5	O75197-1.2	L755I	Pathogenic	0.806
LRP5	O75197-1.2	L755K	Pathogenic	0.972
LRP5	O75197-1.2	L755M	Pathogenic	0.749
LRP5	O75197-1.2	L755N	Pathogenic	0.993
LRP5	O75197-1.2	L755P	Pathogenic	0.998
LRP5	O75197-1.2	L755Q	Pathogenic	0.986
LRP5	O75197-1.2	L755R	Pathogenic	0.971
LRP5	O75197-1.2	L755S	Pathogenic	0.987
LRP5	O75197-1.2	L755T	Pathogenic	0.971
LRP5	O75197-1.2	L755V	Pathogenic	0.897
LRP5	O75197-1.2	L755W	Pathogenic	0.996
LRP5	O75197-1.2	L755Y	Pathogenic	0.985
LRP5	O75197-1.2	V756A	Pathogenic	0.881
LRP5	O75197-1.2	V756C	Pathogenic	0.977
LRP5	O75197-1.2	V756D	Pathogenic	0.988
LRP5	O75197-1.2	V756E	Pathogenic	0.969
LRP5	O75197-1.2	V756F	Pathogenic	0.969
LRP5	O75197-1.2	V756G	Pathogenic	0.994
LRP5	O75197-1.2	V756H	Pathogenic	0.995
LRP5	O75197-1.2	V756I	Neutral	0.267
LRP5	O75197-1.2	V756K	Pathogenic	0.956
LRP5	O75197-1.2	V756L	Pathogenic	0.787
LRP5	O75197-1.2	V756M	Pathogenic	0.849
LRP5	O75197-1.2	V756N	Pathogenic	0.99
LRP5	O75197-1.2	V756P	Pathogenic	0.99
LRP5	O75197-1.2	V756Q	Pathogenic	0.978
LRP5	O75197-1.2	V756R	Pathogenic	0.985
LRP5	O75197-1.2	V756S	Pathogenic	0.981
LRP5	O75197-1.2	V756T	Pathogenic	0.881
LRP5	O75197-1.2	V756W	Pathogenic	0.995
LRP5	O75197-1.2	V756Y	Pathogenic	0.976
LRP5	O75197-1.2	W757A	Pathogenic	0.996
LRP5	O75197-1.2	W757C	Pathogenic	0.994
LRP5	O75197-1.2	W757D	Pathogenic	0.997
LRP5	O75197-1.2	W757E	Pathogenic	0.992
LRP5	O75197-1.2	W757F	Pathogenic	0.927
LRP5	O75197-1.2	W757G	Pathogenic	0.984
LRP5	O75197-1.2	W757H	Pathogenic	0.987
LRP5	O75197-1.2	W757I	Pathogenic	0.999
LRP5	O75197-1.2	W757K	Pathogenic	0.989
LRP5	O75197-1.2	W757L	Pathogenic	0.997
LRP5	O75197-1.2	W757M	Pathogenic	0.986
LRP5	O75197-1.2	W757N	Pathogenic	0.997
LRP5	O75197-1.2	W757P	Pathogenic	0.999
LRP5	O75197-1.2	W757Q	Pathogenic	0.983
LRP5	O75197-1.2	W757R	Pathogenic	0.989
LRP5	O75197-1.2	W757S	Pathogenic	0.995
LRP5	O75197-1.2	W757T	Pathogenic	0.988
LRP5	O75197-1.2	W757V	Pathogenic	0.998
LRP5	O75197-1.2	W757Y	Pathogenic	0.666
LRP5	O75197-1.2	R758A	Neutral	0.178
LRP5	O75197-1.2	R758C	Pathogenic	0.53
LRP5	O75197-1.2	R758D	Pathogenic	0.642
LRP5	O75197-1.2	R758E	Neutral	0.15
LRP5	O75197-1.2	R758F	Neutral	0.372
LRP5	O75197-1.2	R758G	Neutral	0.456
LRP5	O75197-1.2	R758H	Neutral	0.083
LRP5	O75197-1.2	R758I	Neutral	0.365
LRP5	O75197-1.2	R758K	Neutral	0.027
LRP5	O75197-1.2	R758L	Neutral	0.172
LRP5	O75197-1.2	R758M	Neutral	0.094
LRP5	O75197-1.2	R758N	Neutral	0.144
LRP5	O75197-1.2	R758P	Neutral	0.321
LRP5	O75197-1.2	R758Q	Neutral	0.039
LRP5	O75197-1.2	R758S	Neutral	0.229
LRP5	O75197-1.2	R758T	Neutral	0.191
LRP5	O75197-1.2	R758V	Neutral	0.485
LRP5	O75197-1.2	R758W	Neutral	0.281
LRP5	O75197-1.2	R758Y	Neutral	0.292
LRP5	O75197-1.2	D759A	Pathogenic	0.985
LRP5	O75197-1.2	D759C	Pathogenic	0.991
LRP5	O75197-1.2	D759E	Pathogenic	0.637
LRP5	O75197-1.2	D759F	Pathogenic	0.98
LRP5	O75197-1.2	D759G	Pathogenic	0.964
LRP5	O75197-1.2	D759H	Pathogenic	0.961
LRP5	O75197-1.2	D759I	Pathogenic	0.981
LRP5	O75197-1.2	D759K	Pathogenic	0.978
LRP5	O75197-1.2	D759L	Pathogenic	0.994
LRP5	O75197-1.2	D759M	Pathogenic	0.988
LRP5	O75197-1.2	D759N	Pathogenic	0.841
LRP5	O75197-1.2	D759P	Pathogenic	0.938
LRP5	O75197-1.2	D759Q	Pathogenic	0.917
LRP5	O75197-1.2	D759R	Pathogenic	0.992
LRP5	O75197-1.2	D759S	Pathogenic	0.905
LRP5	O75197-1.2	D759T	Pathogenic	0.958
LRP5	O75197-1.2	D759V	Pathogenic	0.989
LRP5	O75197-1.2	D759W	Pathogenic	0.99
LRP5	O75197-1.2	D759Y	Pathogenic	0.99
LRP5	O75197-1.2	L760A	Pathogenic	0.948
LRP5	O75197-1.2	L760C	Pathogenic	0.972
LRP5	O75197-1.2	L760D	Pathogenic	0.995
LRP5	O75197-1.2	L760E	Pathogenic	0.987
LRP5	O75197-1.2	L760F	Pathogenic	0.954
LRP5	O75197-1.2	L760G	Pathogenic	0.997
LRP5	O75197-1.2	L760H	Pathogenic	0.994
LRP5	O75197-1.2	L760I	Pathogenic	0.693
LRP5	O75197-1.2	L760K	Pathogenic	0.95
LRP5	O75197-1.2	L760M	Pathogenic	0.62
LRP5	O75197-1.2	L760N	Pathogenic	0.987
LRP5	O75197-1.2	L760P	Pathogenic	0.996
LRP5	O75197-1.2	L760Q	Pathogenic	0.974
LRP5	O75197-1.2	L760R	Pathogenic	0.948
LRP5	O75197-1.2	L760S	Pathogenic	0.976
LRP5	O75197-1.2	L760T	Pathogenic	0.948
LRP5	O75197-1.2	L760V	Pathogenic	0.826
LRP5	O75197-1.2	L760W	Pathogenic	0.992
LRP5	O75197-1.2	L760Y	Pathogenic	0.972
LRP5	O75197-1.2	D761A	Pathogenic	0.929
LRP5	O75197-1.2	D761C	Pathogenic	0.957
LRP5	O75197-1.2	D761E	Neutral	0.265
LRP5	O75197-1.2	D761F	Pathogenic	0.911
LRP5	O75197-1.2	D761G	Pathogenic	0.846
LRP5	O75197-1.2	D761H	Pathogenic	0.834
LRP5	O75197-1.2	D761I	Pathogenic	0.912
LRP5	O75197-1.2	D761K	Pathogenic	0.9
LRP5	O75197-1.2	D761L	Pathogenic	0.972
LRP5	O75197-1.2	D761M	Pathogenic	0.945
LRP5	O75197-1.2	D761N	Pathogenic	0.52
LRP5	O75197-1.2	D761P	Pathogenic	0.756
LRP5	O75197-1.2	D761Q	Pathogenic	0.695
LRP5	O75197-1.2	D761R	Pathogenic	0.964
LRP5	O75197-1.2	D761S	Pathogenic	0.661
LRP5	O75197-1.2	D761T	Pathogenic	0.824
LRP5	O75197-1.2	D761V	Pathogenic	0.947
LRP5	O75197-1.2	D761W	Pathogenic	0.952
LRP5	O75197-1.2	D761Y	Pathogenic	0.955
LRP5	O75197-1.2	N762A	Pathogenic	0.715
LRP5	O75197-1.2	N762C	Pathogenic	0.812
LRP5	O75197-1.2	N762D	Neutral	0.152
LRP5	O75197-1.2	N762E	Neutral	0.378
LRP5	O75197-1.2	N762F	Pathogenic	0.667
LRP5	O75197-1.2	N762G	Neutral	0.257
LRP5	O75197-1.2	N762H	Neutral	0.095
LRP5	O75197-1.2	N762I	Pathogenic	0.668
LRP5	O75197-1.2	N762K	Neutral	0.298
LRP5	O75197-1.2	N762L	Pathogenic	0.688
LRP5	O75197-1.2	N762M	Pathogenic	0.524
LRP5	O75197-1.2	N762P	Pathogenic	0.643
LRP5	O75197-1.2	N762Q	Neutral	0.307
LRP5	O75197-1.2	N762R	Neutral	0.291
LRP5	O75197-1.2	N762S	Neutral	0.109
LRP5	O75197-1.2	N762T	Neutral	0.228
LRP5	O75197-1.2	N762V	Pathogenic	0.778
LRP5	O75197-1.2	N762W	Pathogenic	0.794
LRP5	O75197-1.2	N762Y	Pathogenic	0.577
LRP5	O75197-1.2	P763A	Pathogenic	0.996
LRP5	O75197-1.2	P763C	Pathogenic	1.0
LRP5	O75197-1.2	P763D	Pathogenic	0.989
LRP5	O75197-1.2	P763E	Pathogenic	0.99
LRP5	O75197-1.2	P763F	Pathogenic	1.0
LRP5	O75197-1.2	P763G	Pathogenic	0.998
LRP5	O75197-1.2	P763H	Pathogenic	0.998
LRP5	O75197-1.2	P763I	Pathogenic	0.999
LRP5	O75197-1.2	P763K	Pathogenic	0.985
LRP5	O75197-1.2	P763L	Pathogenic	0.999
LRP5	O75197-1.2	P763M	Pathogenic	0.998
LRP5	O75197-1.2	P763N	Pathogenic	0.997
LRP5	O75197-1.2	P763Q	Pathogenic	0.993
LRP5	O75197-1.2	P763R	Pathogenic	0.995
LRP5	O75197-1.2	P763S	Pathogenic	0.994
LRP5	O75197-1.2	P763T	Pathogenic	0.995
LRP5	O75197-1.2	P763V	Pathogenic	0.998
LRP5	O75197-1.2	P763W	Pathogenic	1.0
LRP5	O75197-1.2	P763Y	Pathogenic	1.0
LRP5	O75197-1.2	R764A	Pathogenic	0.969
LRP5	O75197-1.2	R764C	Pathogenic	0.994
LRP5	O75197-1.2	R764D	Pathogenic	0.996
LRP5	O75197-1.2	R764E	Pathogenic	0.962
LRP5	O75197-1.2	R764F	Pathogenic	0.988
LRP5	O75197-1.2	R764G	Pathogenic	0.992
LRP5	O75197-1.2	R764H	Pathogenic	0.928
LRP5	O75197-1.2	R764I	Pathogenic	0.988
LRP5	O75197-1.2	R764K	Pathogenic	0.797
LRP5	O75197-1.2	R764L	Pathogenic	0.967
LRP5	O75197-1.2	R764M	Pathogenic	0.937
LRP5	O75197-1.2	R764N	Pathogenic	0.96
LRP5	O75197-1.2	R764P	Pathogenic	0.985
LRP5	O75197-1.2	R764Q	Pathogenic	0.853
LRP5	O75197-1.2	R764S	Pathogenic	0.977
LRP5	O75197-1.2	R764T	Pathogenic	0.971
LRP5	O75197-1.2	R764V	Pathogenic	0.993
LRP5	O75197-1.2	R764W	Pathogenic	0.982
LRP5	O75197-1.2	R764Y	Pathogenic	0.983
LRP5	O75197-1.2	S765A	Neutral	0.114
LRP5	O75197-1.2	S765C	Neutral	0.391
LRP5	O75197-1.2	S765D	Neutral	0.213
LRP5	O75197-1.2	S765E	Neutral	0.228
LRP5	O75197-1.2	S765F	Neutral	0.467
LRP5	O75197-1.2	S765G	Neutral	0.332
LRP5	O75197-1.2	S765H	Pathogenic	0.566
LRP5	O75197-1.2	S765I	Neutral	0.468
LRP5	O75197-1.2	S765K	Neutral	0.171
LRP5	O75197-1.2	S765L	Neutral	0.491
LRP5	O75197-1.2	S765M	Neutral	0.326
LRP5	O75197-1.2	S765N	Neutral	0.093
LRP5	O75197-1.2	S765P	Neutral	0.447
LRP5	O75197-1.2	S765Q	Neutral	0.299
LRP5	O75197-1.2	S765R	Neutral	0.378
LRP5	O75197-1.2	S765T	Neutral	0.116
LRP5	O75197-1.2	S765V	Pathogenic	0.606
LRP5	O75197-1.2	S765W	Pathogenic	0.628
LRP5	O75197-1.2	S765Y	Pathogenic	0.646
LRP5	O75197-1.2	L766A	Pathogenic	0.945
LRP5	O75197-1.2	L766C	Pathogenic	0.97
LRP5	O75197-1.2	L766D	Pathogenic	0.995
LRP5	O75197-1.2	L766E	Pathogenic	0.986
LRP5	O75197-1.2	L766F	Pathogenic	0.951
LRP5	O75197-1.2	L766G	Pathogenic	0.997
LRP5	O75197-1.2	L766H	Pathogenic	0.993
LRP5	O75197-1.2	L766I	Pathogenic	0.678
LRP5	O75197-1.2	L766K	Pathogenic	0.946
LRP5	O75197-1.2	L766M	Pathogenic	0.603
LRP5	O75197-1.2	L766N	Pathogenic	0.987
LRP5	O75197-1.2	L766P	Pathogenic	0.996
LRP5	O75197-1.2	L766Q	Pathogenic	0.972
LRP5	O75197-1.2	L766R	Pathogenic	0.944
LRP5	O75197-1.2	L766S	Pathogenic	0.975
LRP5	O75197-1.2	L766T	Pathogenic	0.945
LRP5	O75197-1.2	L766V	Pathogenic	0.816
LRP5	O75197-1.2	L766W	Pathogenic	0.991
LRP5	O75197-1.2	L766Y	Pathogenic	0.97
LRP5	O75197-1.2	A767C	Pathogenic	0.975
LRP5	O75197-1.2	A767D	Pathogenic	0.996
LRP5	O75197-1.2	A767E	Pathogenic	0.989
LRP5	O75197-1.2	A767F	Pathogenic	0.994
LRP5	O75197-1.2	A767G	Pathogenic	0.982
LRP5	O75197-1.2	A767H	Pathogenic	0.998
LRP5	O75197-1.2	A767I	Pathogenic	0.981
LRP5	O75197-1.2	A767K	Pathogenic	0.984
LRP5	O75197-1.2	A767L	Pathogenic	0.983
LRP5	O75197-1.2	A767M	Pathogenic	0.989
LRP5	O75197-1.2	A767N	Pathogenic	0.996
LRP5	O75197-1.2	A767P	Pathogenic	0.993
LRP5	O75197-1.2	A767Q	Pathogenic	0.992
LRP5	O75197-1.2	A767R	Pathogenic	0.984
LRP5	O75197-1.2	A767S	Pathogenic	0.946
LRP5	O75197-1.2	A767T	Pathogenic	0.985
LRP5	O75197-1.2	A767V	Pathogenic	0.968
LRP5	O75197-1.2	A767W	Pathogenic	0.997
LRP5	O75197-1.2	A767Y	Pathogenic	0.997
LRP5	O75197-1.2	L768A	Pathogenic	0.971
LRP5	O75197-1.2	L768C	Pathogenic	0.984
LRP5	O75197-1.2	L768D	Pathogenic	0.997
LRP5	O75197-1.2	L768E	Pathogenic	0.993
LRP5	O75197-1.2	L768F	Pathogenic	0.974
LRP5	O75197-1.2	L768G	Pathogenic	0.999
LRP5	O75197-1.2	L768H	Pathogenic	0.996
LRP5	O75197-1.2	L768I	Pathogenic	0.803
LRP5	O75197-1.2	L768K	Pathogenic	0.971
LRP5	O75197-1.2	L768M	Pathogenic	0.746
LRP5	O75197-1.2	L768N	Pathogenic	0.993
LRP5	O75197-1.2	L768P	Pathogenic	0.998
LRP5	O75197-1.2	L768Q	Pathogenic	0.985
LRP5	O75197-1.2	L768R	Pathogenic	0.97
LRP5	O75197-1.2	L768S	Pathogenic	0.987
LRP5	O75197-1.2	L768T	Pathogenic	0.971
LRP5	O75197-1.2	L768V	Pathogenic	0.896
LRP5	O75197-1.2	L768W	Pathogenic	0.995
LRP5	O75197-1.2	L768Y	Pathogenic	0.984
LRP5	O75197-1.2	D769A	Pathogenic	0.988
LRP5	O75197-1.2	D769C	Pathogenic	0.993
LRP5	O75197-1.2	D769E	Pathogenic	0.686
LRP5	O75197-1.2	D769F	Pathogenic	0.984
LRP5	O75197-1.2	D769G	Pathogenic	0.971
LRP5	O75197-1.2	D769H	Pathogenic	0.968
LRP5	O75197-1.2	D769I	Pathogenic	0.984
LRP5	O75197-1.2	D769K	Pathogenic	0.982
LRP5	O75197-1.2	D769L	Pathogenic	0.995
LRP5	O75197-1.2	D769M	Pathogenic	0.991
LRP5	O75197-1.2	D769N	Pathogenic	0.868
LRP5	O75197-1.2	D769P	Pathogenic	0.95
LRP5	O75197-1.2	D769Q	Pathogenic	0.933
LRP5	O75197-1.2	D769R	Pathogenic	0.994
LRP5	O75197-1.2	D769S	Pathogenic	0.922
LRP5	O75197-1.2	D769T	Pathogenic	0.966
LRP5	O75197-1.2	D769V	Pathogenic	0.991
LRP5	O75197-1.2	D769W	Pathogenic	0.992
LRP5	O75197-1.2	D769Y	Pathogenic	0.992
LRP5	O75197-1.2	P770A	Pathogenic	0.996
LRP5	O75197-1.2	P770C	Pathogenic	1.0
LRP5	O75197-1.2	P770D	Pathogenic	0.989
LRP5	O75197-1.2	P770E	Pathogenic	0.99
LRP5	O75197-1.2	P770F	Pathogenic	1.0
LRP5	O75197-1.2	P770G	Pathogenic	0.998
LRP5	O75197-1.2	P770H	Pathogenic	0.998
LRP5	O75197-1.2	P770I	Pathogenic	0.999
LRP5	O75197-1.2	P770K	Pathogenic	0.985
LRP5	O75197-1.2	P770L	Pathogenic	0.999
LRP5	O75197-1.2	P770M	Pathogenic	0.998
LRP5	O75197-1.2	P770N	Pathogenic	0.997
LRP5	O75197-1.2	P770Q	Pathogenic	0.993
LRP5	O75197-1.2	P770R	Pathogenic	0.995
LRP5	O75197-1.2	P770S	Pathogenic	0.994
LRP5	O75197-1.2	P770T	Pathogenic	0.995
LRP5	O75197-1.2	P770V	Pathogenic	0.998
LRP5	O75197-1.2	P770W	Pathogenic	1.0
LRP5	O75197-1.2	P770Y	Pathogenic	1.0
LRP5	O75197-1.2	T771A	Neutral	0.086
LRP5	O75197-1.2	T771C	Neutral	0.139
LRP5	O75197-1.2	T771D	Neutral	0.111
LRP5	O75197-1.2	T771E	Neutral	0.121
LRP5	O75197-1.2	T771F	Neutral	0.185
LRP5	O75197-1.2	T771G	Neutral	0.413
LRP5	O75197-1.2	T771H	Neutral	0.45
LRP5	O75197-1.2	T771I	Neutral	0.07
LRP5	O75197-1.2	T771K	Neutral	0.088
LRP5	O75197-1.2	T771L	Neutral	0.076
LRP5	O75197-1.2	T771M	Neutral	0.111
LRP5	O75197-1.2	T771N	Neutral	0.045
LRP5	O75197-1.2	T771P	Neutral	0.171
LRP5	O75197-1.2	T771Q	Neutral	0.165
LRP5	O75197-1.2	T771R	Neutral	0.085
LRP5	O75197-1.2	T771S	Neutral	0.025
LRP5	O75197-1.2	T771V	Neutral	0.041
LRP5	O75197-1.2	T771W	Neutral	0.125
LRP5	O75197-1.2	T771Y	Neutral	0.32
LRP5	O75197-1.2	K772A	Neutral	0.202
LRP5	O75197-1.2	K772C	Pathogenic	0.569
LRP5	O75197-1.2	K772D	Neutral	0.408
LRP5	O75197-1.2	K772E	Neutral	0.064
LRP5	O75197-1.2	K772F	Neutral	0.41
LRP5	O75197-1.2	K772G	Neutral	0.496
LRP5	O75197-1.2	K772H	Neutral	0.243
LRP5	O75197-1.2	K772I	Neutral	0.403
LRP5	O75197-1.2	K772L	Neutral	0.195
LRP5	O75197-1.2	K772M	Neutral	0.108
LRP5	O75197-1.2	K772N	Neutral	0.164
LRP5	O75197-1.2	K772P	Neutral	0.154
LRP5	O75197-1.2	K772Q	Neutral	0.045
LRP5	O75197-1.2	K772R	Neutral	0.03
LRP5	O75197-1.2	K772S	Neutral	0.103
LRP5	O75197-1.2	K772T	Neutral	0.216
LRP5	O75197-1.2	K772V	Neutral	0.266
LRP5	O75197-1.2	K772W	Neutral	0.305
LRP5	O75197-1.2	K772Y	Neutral	0.322
LRP5	O75197-1.2	G773A	Pathogenic	0.989
LRP5	O75197-1.2	G773C	Pathogenic	0.999
LRP5	O75197-1.2	G773D	Pathogenic	0.994
LRP5	O75197-1.2	G773E	Pathogenic	0.998
LRP5	O75197-1.2	G773F	Pathogenic	0.998
LRP5	O75197-1.2	G773H	Pathogenic	0.999
LRP5	O75197-1.2	G773I	Pathogenic	0.999
LRP5	O75197-1.2	G773K	Pathogenic	0.997
LRP5	O75197-1.2	G773L	Pathogenic	0.999
LRP5	O75197-1.2	G773M	Pathogenic	0.999
LRP5	O75197-1.2	G773N	Pathogenic	0.985
LRP5	O75197-1.2	G773P	Pathogenic	0.998
LRP5	O75197-1.2	G773Q	Pathogenic	0.999
LRP5	O75197-1.2	G773R	Pathogenic	0.997
LRP5	O75197-1.2	G773S	Pathogenic	0.991
LRP5	O75197-1.2	G773T	Pathogenic	0.999
LRP5	O75197-1.2	G773V	Pathogenic	0.999
LRP5	O75197-1.2	G773W	Pathogenic	0.992
LRP5	O75197-1.2	G773Y	Pathogenic	0.999
LRP5	O75197-1.2	Y774A	Pathogenic	0.919
LRP5	O75197-1.2	Y774C	Pathogenic	0.954
LRP5	O75197-1.2	Y774D	Pathogenic	0.932
LRP5	O75197-1.2	Y774E	Pathogenic	0.839
LRP5	O75197-1.2	Y774F	Neutral	0.04
LRP5	O75197-1.2	Y774G	Pathogenic	0.962
LRP5	O75197-1.2	Y774H	Neutral	0.109
LRP5	O75197-1.2	Y774I	Pathogenic	0.775
LRP5	O75197-1.2	Y774K	Pathogenic	0.799
LRP5	O75197-1.2	Y774L	Pathogenic	0.791
LRP5	O75197-1.2	Y774M	Pathogenic	0.852
LRP5	O75197-1.2	Y774N	Pathogenic	0.841
LRP5	O75197-1.2	Y774P	Pathogenic	0.981
LRP5	O75197-1.2	Y774Q	Pathogenic	0.715
LRP5	O75197-1.2	Y774R	Pathogenic	0.796
LRP5	O75197-1.2	Y774S	Pathogenic	0.894
LRP5	O75197-1.2	Y774T	Pathogenic	0.919
LRP5	O75197-1.2	Y774V	Pathogenic	0.85
LRP5	O75197-1.2	Y774W	Neutral	0.075
LRP5	O75197-1.2	I775A	Neutral	0.316
LRP5	O75197-1.2	I775C	Neutral	0.466
LRP5	O75197-1.2	I775D	Pathogenic	0.629
LRP5	O75197-1.2	I775E	Pathogenic	0.663
LRP5	O75197-1.2	I775F	Neutral	0.381
LRP5	O75197-1.2	I775G	Pathogenic	0.906
LRP5	O75197-1.2	I775H	Pathogenic	0.799
LRP5	O75197-1.2	I775K	Pathogenic	0.591
LRP5	O75197-1.2	I775L	Neutral	0.059
LRP5	O75197-1.2	I775M	Neutral	0.111
LRP5	O75197-1.2	I775N	Pathogenic	0.665
LRP5	O75197-1.2	I775P	Pathogenic	0.865
LRP5	O75197-1.2	I775Q	Pathogenic	0.742
LRP5	O75197-1.2	I775R	Pathogenic	0.583
LRP5	O75197-1.2	I775S	Pathogenic	0.511
LRP5	O75197-1.2	I775T	Neutral	0.315
LRP5	O75197-1.2	I775V	Neutral	0.013
LRP5	O75197-1.2	I775W	Pathogenic	0.918
LRP5	O75197-1.2	I775Y	Neutral	0.469
LRP5	O75197-1.2	Y776A	Pathogenic	0.999
LRP5	O75197-1.2	Y776C	Pathogenic	1.0
LRP5	O75197-1.2	Y776D	Pathogenic	0.999
LRP5	O75197-1.2	Y776E	Pathogenic	0.998
LRP5	O75197-1.2	Y776F	Pathogenic	0.824
LRP5	O75197-1.2	Y776G	Pathogenic	1.0
LRP5	O75197-1.2	Y776H	Pathogenic	0.933
LRP5	O75197-1.2	Y776I	Pathogenic	0.997
LRP5	O75197-1.2	Y776K	Pathogenic	0.998
LRP5	O75197-1.2	Y776L	Pathogenic	0.998
LRP5	O75197-1.2	Y776M	Pathogenic	0.998
LRP5	O75197-1.2	Y776N	Pathogenic	0.998
LRP5	O75197-1.2	Y776P	Pathogenic	1.0
LRP5	O75197-1.2	Y776Q	Pathogenic	0.996
LRP5	O75197-1.2	Y776R	Pathogenic	0.998
LRP5	O75197-1.2	Y776S	Pathogenic	0.999
LRP5	O75197-1.2	Y776T	Pathogenic	0.999
LRP5	O75197-1.2	Y776V	Pathogenic	0.998
LRP5	O75197-1.2	Y776W	Pathogenic	0.902
LRP5	O75197-1.2	W777A	Pathogenic	0.999
LRP5	O75197-1.2	W777C	Pathogenic	0.999
LRP5	O75197-1.2	W777D	Pathogenic	0.999
LRP5	O75197-1.2	W777E	Pathogenic	0.999
LRP5	O75197-1.2	W777F	Pathogenic	0.986
LRP5	O75197-1.2	W777G	Pathogenic	0.997
LRP5	O75197-1.2	W777H	Pathogenic	0.998
LRP5	O75197-1.2	W777I	Pathogenic	1.0
LRP5	O75197-1.2	W777K	Pathogenic	0.998
LRP5	O75197-1.2	W777L	Pathogenic	0.999
LRP5	O75197-1.2	W777M	Pathogenic	0.998
LRP5	O75197-1.2	W777N	Pathogenic	1.0
LRP5	O75197-1.2	W777P	Pathogenic	1.0
LRP5	O75197-1.2	W777Q	Pathogenic	0.997
LRP5	O75197-1.2	W777R	Pathogenic	0.998
LRP5	O75197-1.2	W777S	Pathogenic	0.999
LRP5	O75197-1.2	W777T	Pathogenic	0.998
LRP5	O75197-1.2	W777V	Pathogenic	1.0
LRP5	O75197-1.2	W777Y	Pathogenic	0.92
LRP5	O75197-1.2	T778A	Pathogenic	0.946
LRP5	O75197-1.2	T778C	Pathogenic	0.968
LRP5	O75197-1.2	T778D	Pathogenic	0.958
LRP5	O75197-1.2	T778E	Pathogenic	0.962
LRP5	O75197-1.2	T778F	Pathogenic	0.977
LRP5	O75197-1.2	T778G	Pathogenic	0.992
LRP5	O75197-1.2	T778H	Pathogenic	0.993
LRP5	O75197-1.2	T778I	Pathogenic	0.932
LRP5	O75197-1.2	T778K	Pathogenic	0.947
LRP5	O75197-1.2	T778L	Pathogenic	0.938
LRP5	O75197-1.2	T778M	Pathogenic	0.958
LRP5	O75197-1.2	T778N	Pathogenic	0.898
LRP5	O75197-1.2	T778P	Pathogenic	0.974
LRP5	O75197-1.2	T778Q	Pathogenic	0.973
LRP5	O75197-1.2	T778R	Pathogenic	0.945
LRP5	O75197-1.2	T778S	Pathogenic	0.823
LRP5	O75197-1.2	T778V	Pathogenic	0.888
LRP5	O75197-1.2	T778W	Pathogenic	0.964
LRP5	O75197-1.2	T778Y	Pathogenic	0.989
LRP5	O75197-1.2	E779A	Pathogenic	0.971
LRP5	O75197-1.2	E779C	Pathogenic	0.998
LRP5	O75197-1.2	E779D	Pathogenic	0.721
LRP5	O75197-1.2	E779F	Pathogenic	0.988
LRP5	O75197-1.2	E779G	Pathogenic	0.992
LRP5	O75197-1.2	E779H	Pathogenic	0.932
LRP5	O75197-1.2	E779I	Pathogenic	0.988
LRP5	O75197-1.2	E779K	Pathogenic	0.864
LRP5	O75197-1.2	E779L	Pathogenic	0.989
LRP5	O75197-1.2	E779M	Pathogenic	0.979
LRP5	O75197-1.2	E779N	Pathogenic	0.963
LRP5	O75197-1.2	E779P	Pathogenic	0.96
LRP5	O75197-1.2	E779Q	Pathogenic	0.671
LRP5	O75197-1.2	E779R	Pathogenic	0.949
LRP5	O75197-1.2	E779S	Pathogenic	0.938
LRP5	O75197-1.2	E779T	Pathogenic	0.974
LRP5	O75197-1.2	E779V	Pathogenic	0.98
LRP5	O75197-1.2	E779W	Pathogenic	0.982
LRP5	O75197-1.2	E779Y	Pathogenic	0.983
LRP5	O75197-1.2	W780A	Pathogenic	0.999
LRP5	O75197-1.2	W780C	Pathogenic	0.999
LRP5	O75197-1.2	W780D	Pathogenic	0.999
LRP5	O75197-1.2	W780E	Pathogenic	0.999
LRP5	O75197-1.2	W780F	Pathogenic	0.986
LRP5	O75197-1.2	W780G	Pathogenic	0.997
LRP5	O75197-1.2	W780H	Pathogenic	0.998
LRP5	O75197-1.2	W780I	Pathogenic	1.0
LRP5	O75197-1.2	W780K	Pathogenic	0.998
LRP5	O75197-1.2	W780L	Pathogenic	0.999
LRP5	O75197-1.2	W780M	Pathogenic	0.998
LRP5	O75197-1.2	W780N	Pathogenic	1.0
LRP5	O75197-1.2	W780P	Pathogenic	1.0
LRP5	O75197-1.2	W780Q	Pathogenic	0.997
LRP5	O75197-1.2	W780R	Pathogenic	0.998
LRP5	O75197-1.2	W780S	Pathogenic	0.999
LRP5	O75197-1.2	W780T	Pathogenic	0.998
LRP5	O75197-1.2	W780V	Pathogenic	1.0
LRP5	O75197-1.2	W780Y	Pathogenic	0.92
LRP5	O75197-1.2	G781A	Pathogenic	0.985
LRP5	O75197-1.2	G781C	Pathogenic	0.999
LRP5	O75197-1.2	G781D	Pathogenic	0.992
LRP5	O75197-1.2	G781E	Pathogenic	0.998
LRP5	O75197-1.2	G781F	Pathogenic	0.998
LRP5	O75197-1.2	G781H	Pathogenic	0.998
LRP5	O75197-1.2	G781I	Pathogenic	0.999
LRP5	O75197-1.2	G781K	Pathogenic	0.997
LRP5	O75197-1.2	G781L	Pathogenic	0.999
LRP5	O75197-1.2	G781M	Pathogenic	0.999
LRP5	O75197-1.2	G781N	Pathogenic	0.98
LRP5	O75197-1.2	G781P	Pathogenic	0.998
LRP5	O75197-1.2	G781Q	Pathogenic	0.998
LRP5	O75197-1.2	G781R	Pathogenic	0.997
LRP5	O75197-1.2	G781S	Pathogenic	0.988
LRP5	O75197-1.2	G781T	Pathogenic	0.998
LRP5	O75197-1.2	G781V	Pathogenic	0.999
LRP5	O75197-1.2	G781W	Pathogenic	0.989
LRP5	O75197-1.2	G781Y	Pathogenic	0.999
LRP5	O75197-1.2	G782A	Pathogenic	0.842
LRP5	O75197-1.2	G782C	Pathogenic	0.988
LRP5	O75197-1.2	G782D	Pathogenic	0.912
LRP5	O75197-1.2	G782E	Pathogenic	0.972
LRP5	O75197-1.2	G782F	Pathogenic	0.973
LRP5	O75197-1.2	G782H	Pathogenic	0.982
LRP5	O75197-1.2	G782I	Pathogenic	0.991
LRP5	O75197-1.2	G782K	Pathogenic	0.96
LRP5	O75197-1.2	G782L	Pathogenic	0.992
LRP5	O75197-1.2	G782M	Pathogenic	0.984
LRP5	O75197-1.2	G782N	Pathogenic	0.796
LRP5	O75197-1.2	G782P	Pathogenic	0.97
LRP5	O75197-1.2	G782Q	Pathogenic	0.98
LRP5	O75197-1.2	G782R	Pathogenic	0.959
LRP5	O75197-1.2	G782S	Pathogenic	0.87
LRP5	O75197-1.2	G782T	Pathogenic	0.98
LRP5	O75197-1.2	G782V	Pathogenic	0.984
LRP5	O75197-1.2	G782W	Pathogenic	0.881
LRP5	O75197-1.2	G782Y	Pathogenic	0.987
LRP5	O75197-1.2	K783A	Pathogenic	0.63
LRP5	O75197-1.2	K783C	Pathogenic	0.899
LRP5	O75197-1.2	K783D	Pathogenic	0.823
LRP5	O75197-1.2	K783E	Neutral	0.315
LRP5	O75197-1.2	K783F	Pathogenic	0.824
LRP5	O75197-1.2	K783G	Pathogenic	0.869
LRP5	O75197-1.2	K783H	Pathogenic	0.684
LRP5	O75197-1.2	K783I	Pathogenic	0.82
LRP5	O75197-1.2	K783L	Pathogenic	0.621
LRP5	O75197-1.2	K783M	Neutral	0.45
LRP5	O75197-1.2	K783N	Pathogenic	0.57
LRP5	O75197-1.2	K783P	Pathogenic	0.551
LRP5	O75197-1.2	K783Q	Neutral	0.242
LRP5	O75197-1.2	K783R	Neutral	0.172
LRP5	O75197-1.2	K783S	Neutral	0.435
LRP5	O75197-1.2	K783T	Pathogenic	0.651
LRP5	O75197-1.2	K783V	Pathogenic	0.71
LRP5	O75197-1.2	K783W	Pathogenic	0.748
LRP5	O75197-1.2	K783Y	Pathogenic	0.762
LRP5	O75197-1.2	P784A	Pathogenic	0.978
LRP5	O75197-1.2	P784C	Pathogenic	0.998
LRP5	O75197-1.2	P784D	Pathogenic	0.945
LRP5	O75197-1.2	P784E	Pathogenic	0.95
LRP5	O75197-1.2	P784F	Pathogenic	0.998
LRP5	O75197-1.2	P784G	Pathogenic	0.99
LRP5	O75197-1.2	P784H	Pathogenic	0.991
LRP5	O75197-1.2	P784I	Pathogenic	0.995
LRP5	O75197-1.2	P784K	Pathogenic	0.93
LRP5	O75197-1.2	P784L	Pathogenic	0.996
LRP5	O75197-1.2	P784M	Pathogenic	0.992
LRP5	O75197-1.2	P784N	Pathogenic	0.984
LRP5	O75197-1.2	P784Q	Pathogenic	0.965
LRP5	O75197-1.2	P784R	Pathogenic	0.975
LRP5	O75197-1.2	P784S	Pathogenic	0.97
LRP5	O75197-1.2	P784T	Pathogenic	0.977
LRP5	O75197-1.2	P784V	Pathogenic	0.992
LRP5	O75197-1.2	P784W	Pathogenic	0.998
LRP5	O75197-1.2	P784Y	Pathogenic	0.998
LRP5	O75197-1.2	R785A	Neutral	0.184
LRP5	O75197-1.2	R785C	Pathogenic	0.54
LRP5	O75197-1.2	R785D	Pathogenic	0.651
LRP5	O75197-1.2	R785E	Neutral	0.156
LRP5	O75197-1.2	R785F	Neutral	0.382
LRP5	O75197-1.2	R785G	Neutral	0.466
LRP5	O75197-1.2	R785H	Neutral	0.086
LRP5	O75197-1.2	R785I	Neutral	0.374
LRP5	O75197-1.2	R785K	Neutral	0.028
LRP5	O75197-1.2	R785L	Neutral	0.177
LRP5	O75197-1.2	R785M	Neutral	0.097
LRP5	O75197-1.2	R785N	Neutral	0.149
LRP5	O75197-1.2	R785P	Neutral	0.33
LRP5	O75197-1.2	R785Q	Neutral	0.04
LRP5	O75197-1.2	R785S	Neutral	0.236
LRP5	O75197-1.2	R785T	Neutral	0.197
LRP5	O75197-1.2	R785V	Neutral	0.495
LRP5	O75197-1.2	R785W	Neutral	0.289
LRP5	O75197-1.2	R785Y	Neutral	0.301
LRP5	O75197-1.2	I786A	Pathogenic	0.983
LRP5	O75197-1.2	I786C	Pathogenic	0.991
LRP5	O75197-1.2	I786D	Pathogenic	0.995
LRP5	O75197-1.2	I786E	Pathogenic	0.996
LRP5	O75197-1.2	I786F	Pathogenic	0.987
LRP5	O75197-1.2	I786G	Pathogenic	0.999
LRP5	O75197-1.2	I786H	Pathogenic	0.998
LRP5	O75197-1.2	I786K	Pathogenic	0.995
LRP5	O75197-1.2	I786L	Pathogenic	0.888
LRP5	O75197-1.2	I786M	Pathogenic	0.941
LRP5	O75197-1.2	I786N	Pathogenic	0.996
LRP5	O75197-1.2	I786P	Pathogenic	0.999
LRP5	O75197-1.2	I786Q	Pathogenic	0.997
LRP5	O75197-1.2	I786R	Pathogenic	0.994
LRP5	O75197-1.2	I786S	Pathogenic	0.993
LRP5	O75197-1.2	I786T	Pathogenic	0.983
LRP5	O75197-1.2	I786V	Pathogenic	0.622
LRP5	O75197-1.2	I786W	Pathogenic	0.999
LRP5	O75197-1.2	I786Y	Pathogenic	0.991
LRP5	O75197-1.2	V787A	Neutral	0.055
LRP5	O75197-1.2	V787C	Neutral	0.251
LRP5	O75197-1.2	V787D	Neutral	0.395
LRP5	O75197-1.2	V787E	Neutral	0.197
LRP5	O75197-1.2	V787F	Neutral	0.196
LRP5	O75197-1.2	V787G	Pathogenic	0.548
LRP5	O75197-1.2	V787H	Pathogenic	0.594
LRP5	O75197-1.2	V787I	Neutral	0.003
LRP5	O75197-1.2	V787K	Neutral	0.146
LRP5	O75197-1.2	V787L	Neutral	0.028
LRP5	O75197-1.2	V787M	Neutral	0.042
LRP5	O75197-1.2	V787N	Neutral	0.433
LRP5	O75197-1.2	V787P	Neutral	0.447
LRP5	O75197-1.2	V787Q	Neutral	0.261
LRP5	O75197-1.2	V787R	Neutral	0.335
LRP5	O75197-1.2	V787S	Neutral	0.286
LRP5	O75197-1.2	V787T	Neutral	0.055
LRP5	O75197-1.2	V787W	Pathogenic	0.587
LRP5	O75197-1.2	V787Y	Neutral	0.242
LRP5	O75197-1.2	R788A	Pathogenic	0.986
LRP5	O75197-1.2	R788C	Pathogenic	0.997
LRP5	O75197-1.2	R788D	Pathogenic	0.998
LRP5	O75197-1.2	R788E	Pathogenic	0.982
LRP5	O75197-1.2	R788F	Pathogenic	0.995
LRP5	O75197-1.2	R788G	Pathogenic	0.996
LRP5	O75197-1.2	R788H	Pathogenic	0.966
LRP5	O75197-1.2	R788I	Pathogenic	0.995
LRP5	O75197-1.2	R788K	Pathogenic	0.896
LRP5	O75197-1.2	R788L	Pathogenic	0.985
LRP5	O75197-1.2	R788M	Pathogenic	0.97
LRP5	O75197-1.2	R788N	Pathogenic	0.981
LRP5	O75197-1.2	R788P	Pathogenic	0.993
LRP5	O75197-1.2	R788Q	Pathogenic	0.927
LRP5	O75197-1.2	R788S	Pathogenic	0.989
LRP5	O75197-1.2	R788T	Pathogenic	0.987
LRP5	O75197-1.2	R788V	Pathogenic	0.997
LRP5	O75197-1.2	R788W	Pathogenic	0.992
LRP5	O75197-1.2	R788Y	Pathogenic	0.992
LRP5	O75197-1.2	A789C	Pathogenic	0.976
LRP5	O75197-1.2	A789D	Pathogenic	0.996
LRP5	O75197-1.2	A789E	Pathogenic	0.99
LRP5	O75197-1.2	A789F	Pathogenic	0.994
LRP5	O75197-1.2	A789G	Pathogenic	0.983
LRP5	O75197-1.2	A789H	Pathogenic	0.998
LRP5	O75197-1.2	A789I	Pathogenic	0.983
LRP5	O75197-1.2	A789K	Pathogenic	0.985
LRP5	O75197-1.2	A789L	Pathogenic	0.984
LRP5	O75197-1.2	A789M	Pathogenic	0.989
LRP5	O75197-1.2	A789N	Pathogenic	0.997
LRP5	O75197-1.2	A789P	Pathogenic	0.994
LRP5	O75197-1.2	A789Q	Pathogenic	0.993
LRP5	O75197-1.2	A789R	Pathogenic	0.985
LRP5	O75197-1.2	A789S	Pathogenic	0.949
LRP5	O75197-1.2	A789T	Pathogenic	0.986
LRP5	O75197-1.2	A789V	Pathogenic	0.97
LRP5	O75197-1.2	A789W	Pathogenic	0.997
LRP5	O75197-1.2	A789Y	Pathogenic	0.997
LRP5	O75197-1.2	F790A	Neutral	0.102
LRP5	O75197-1.2	F790C	Neutral	0.176
LRP5	O75197-1.2	F790D	Neutral	0.12
LRP5	O75197-1.2	F790E	Neutral	0.136
LRP5	O75197-1.2	F790G	Neutral	0.202
LRP5	O75197-1.2	F790H	Neutral	0.033
LRP5	O75197-1.2	F790I	Neutral	0.047
LRP5	O75197-1.2	F790K	Neutral	0.107
LRP5	O75197-1.2	F790L	Neutral	0.044
LRP5	O75197-1.2	F790M	Neutral	0.03
LRP5	O75197-1.2	F790N	Neutral	0.138
LRP5	O75197-1.2	F790P	Pathogenic	0.61
LRP5	O75197-1.2	F790Q	Neutral	0.188
LRP5	O75197-1.2	F790R	Neutral	0.104
LRP5	O75197-1.2	F790S	Neutral	0.077
LRP5	O75197-1.2	F790T	Neutral	0.101
LRP5	O75197-1.2	F790V	Neutral	0.082
LRP5	O75197-1.2	F790W	Neutral	0.011
LRP5	O75197-1.2	F790Y	Neutral	0.001
LRP5	O75197-1.2	M791A	Pathogenic	0.993
LRP5	O75197-1.2	M791C	Pathogenic	0.996
LRP5	O75197-1.2	M791D	Pathogenic	0.998
LRP5	O75197-1.2	M791E	Pathogenic	0.995
LRP5	O75197-1.2	M791F	Pathogenic	0.985
LRP5	O75197-1.2	M791G	Pathogenic	0.999
LRP5	O75197-1.2	M791H	Pathogenic	0.997
LRP5	O75197-1.2	M791I	Pathogenic	0.956
LRP5	O75197-1.2	M791K	Pathogenic	0.979
LRP5	O75197-1.2	M791L	Pathogenic	0.888
LRP5	O75197-1.2	M791N	Pathogenic	0.995
LRP5	O75197-1.2	M791P	Pathogenic	0.998
LRP5	O75197-1.2	M791Q	Pathogenic	0.968
LRP5	O75197-1.2	M791R	Pathogenic	0.978
LRP5	O75197-1.2	M791S	Pathogenic	0.99
LRP5	O75197-1.2	M791T	Pathogenic	0.993
LRP5	O75197-1.2	M791V	Pathogenic	0.972
LRP5	O75197-1.2	M791W	Pathogenic	0.992
LRP5	O75197-1.2	M791Y	Pathogenic	0.996
LRP5	O75197-1.2	D792A	Pathogenic	0.997
LRP5	O75197-1.2	D792C	Pathogenic	0.998
LRP5	O75197-1.2	D792E	Pathogenic	0.907
LRP5	O75197-1.2	D792F	Pathogenic	0.996
LRP5	O75197-1.2	D792G	Pathogenic	0.993
LRP5	O75197-1.2	D792H	Pathogenic	0.993
LRP5	O75197-1.2	D792I	Pathogenic	0.996
LRP5	O75197-1.2	D792K	Pathogenic	0.996
LRP5	O75197-1.2	D792L	Pathogenic	0.999
LRP5	O75197-1.2	D792M	Pathogenic	0.998
LRP5	O75197-1.2	D792N	Pathogenic	0.967
LRP5	O75197-1.2	D792P	Pathogenic	0.988
LRP5	O75197-1.2	D792Q	Pathogenic	0.984
LRP5	O75197-1.2	D792R	Pathogenic	0.999
LRP5	O75197-1.2	D792S	Pathogenic	0.981
LRP5	O75197-1.2	D792T	Pathogenic	0.992
LRP5	O75197-1.2	D792V	Pathogenic	0.998
LRP5	O75197-1.2	D792W	Pathogenic	0.998
LRP5	O75197-1.2	D792Y	Pathogenic	0.998
LRP5	O75197-1.2	G793A	Pathogenic	0.989
LRP5	O75197-1.2	G793C	Pathogenic	0.999
LRP5	O75197-1.2	G793D	Pathogenic	0.994
LRP5	O75197-1.2	G793E	Pathogenic	0.998
LRP5	O75197-1.2	G793F	Pathogenic	0.998
LRP5	O75197-1.2	G793H	Pathogenic	0.999
LRP5	O75197-1.2	G793I	Pathogenic	0.999
LRP5	O75197-1.2	G793K	Pathogenic	0.998
LRP5	O75197-1.2	G793L	Pathogenic	1.0
LRP5	O75197-1.2	G793M	Pathogenic	0.999
LRP5	O75197-1.2	G793N	Pathogenic	0.985
LRP5	O75197-1.2	G793P	Pathogenic	0.998
LRP5	O75197-1.2	G793Q	Pathogenic	0.999
LRP5	O75197-1.2	G793R	Pathogenic	0.997
LRP5	O75197-1.2	G793S	Pathogenic	0.991
LRP5	O75197-1.2	G793T	Pathogenic	0.999
LRP5	O75197-1.2	G793V	Pathogenic	0.999
LRP5	O75197-1.2	G793W	Pathogenic	0.992
LRP5	O75197-1.2	G793Y	Pathogenic	0.999
LRP5	O75197-1.2	T794A	Pathogenic	0.558
LRP5	O75197-1.2	T794C	Pathogenic	0.684
LRP5	O75197-1.2	T794D	Pathogenic	0.625
LRP5	O75197-1.2	T794E	Pathogenic	0.647
LRP5	O75197-1.2	T794F	Pathogenic	0.752
LRP5	O75197-1.2	T794G	Pathogenic	0.904
LRP5	O75197-1.2	T794H	Pathogenic	0.916
LRP5	O75197-1.2	T794I	Pathogenic	0.5
LRP5	O75197-1.2	T794K	Pathogenic	0.563
LRP5	O75197-1.2	T794L	Pathogenic	0.523
LRP5	O75197-1.2	T794M	Pathogenic	0.625
LRP5	O75197-1.2	T794N	Neutral	0.389
LRP5	O75197-1.2	T794P	Pathogenic	0.734
LRP5	O75197-1.2	T794Q	Pathogenic	0.726
LRP5	O75197-1.2	T794R	Pathogenic	0.554
LRP5	O75197-1.2	T794S	Neutral	0.252
LRP5	O75197-1.2	T794V	Neutral	0.364
LRP5	O75197-1.2	T794W	Pathogenic	0.657
LRP5	O75197-1.2	T794Y	Pathogenic	0.863
LRP5	O75197-1.2	N795A	Neutral	0.268
LRP5	O75197-1.2	N795C	Neutral	0.386
LRP5	O75197-1.2	N795D	Neutral	0.026
LRP5	O75197-1.2	N795E	Neutral	0.081
LRP5	O75197-1.2	N795F	Neutral	0.226
LRP5	O75197-1.2	N795G	Neutral	0.048
LRP5	O75197-1.2	N795H	Neutral	0.015
LRP5	O75197-1.2	N795I	Neutral	0.227
LRP5	O75197-1.2	N795K	Neutral	0.058
LRP5	O75197-1.2	N795L	Neutral	0.243
LRP5	O75197-1.2	N795M	Neutral	0.138
LRP5	O75197-1.2	N795P	Neutral	0.208
LRP5	O75197-1.2	N795Q	Neutral	0.061
LRP5	O75197-1.2	N795R	Neutral	0.057
LRP5	O75197-1.2	N795S	Neutral	0.018
LRP5	O75197-1.2	N795T	Neutral	0.041
LRP5	O75197-1.2	N795V	Neutral	0.338
LRP5	O75197-1.2	N795W	Neutral	0.36
LRP5	O75197-1.2	N795Y	Neutral	0.166
LRP5	O75197-1.2	C796A	Neutral	0.084
LRP5	O75197-1.2	C796D	Pathogenic	0.501
LRP5	O75197-1.2	C796E	Pathogenic	0.77
LRP5	O75197-1.2	C796F	Neutral	0.418
LRP5	O75197-1.2	C796G	Pathogenic	0.655
LRP5	O75197-1.2	C796H	Pathogenic	0.683
LRP5	O75197-1.2	C796I	Neutral	0.191
LRP5	O75197-1.2	C796K	Neutral	0.435
LRP5	O75197-1.2	C796L	Neutral	0.206
LRP5	O75197-1.2	C796M	Neutral	0.283
LRP5	O75197-1.2	C796N	Pathogenic	0.537
LRP5	O75197-1.2	C796P	Pathogenic	0.792
LRP5	O75197-1.2	C796Q	Pathogenic	0.613
LRP5	O75197-1.2	C796R	Neutral	0.426
LRP5	O75197-1.2	C796S	Neutral	0.171
LRP5	O75197-1.2	C796T	Neutral	0.213
LRP5	O75197-1.2	C796V	Neutral	0.292
LRP5	O75197-1.2	C796W	Neutral	0.312
LRP5	O75197-1.2	C796Y	Pathogenic	0.589
LRP5	O75197-1.2	M797A	Neutral	0.042
LRP5	O75197-1.2	M797C	Neutral	0.077
LRP5	O75197-1.2	M797D	Neutral	0.139
LRP5	O75197-1.2	M797E	Neutral	0.058
LRP5	O75197-1.2	M797F	Neutral	0.021
LRP5	O75197-1.2	M797G	Neutral	0.231
LRP5	O75197-1.2	M797H	Neutral	0.111
LRP5	O75197-1.2	M797I	Neutral	0.007
LRP5	O75197-1.2	M797K	Neutral	0.015
LRP5	O75197-1.2	M797L	Neutral	0.003
LRP5	O75197-1.2	M797N	Neutral	0.059
LRP5	O75197-1.2	M797P	Neutral	0.167
LRP5	O75197-1.2	M797Q	Neutral	0.01
LRP5	O75197-1.2	M797R	Neutral	0.014
LRP5	O75197-1.2	M797S	Neutral	0.032
LRP5	O75197-1.2	M797T	Neutral	0.042
LRP5	O75197-1.2	M797V	Neutral	0.011
LRP5	O75197-1.2	M797W	Neutral	0.04
LRP5	O75197-1.2	M797Y	Neutral	0.078
LRP5	O75197-1.2	T798A	Pathogenic	0.869
LRP5	O75197-1.2	T798C	Pathogenic	0.919
LRP5	O75197-1.2	T798D	Pathogenic	0.898
LRP5	O75197-1.2	T798E	Pathogenic	0.906
LRP5	O75197-1.2	T798F	Pathogenic	0.941
LRP5	O75197-1.2	T798G	Pathogenic	0.98
LRP5	O75197-1.2	T798H	Pathogenic	0.983
LRP5	O75197-1.2	T798I	Pathogenic	0.84
LRP5	O75197-1.2	T798K	Pathogenic	0.871
LRP5	O75197-1.2	T798L	Pathogenic	0.852
LRP5	O75197-1.2	T798M	Pathogenic	0.898
LRP5	O75197-1.2	T798N	Pathogenic	0.77
LRP5	O75197-1.2	T798P	Pathogenic	0.935
LRP5	O75197-1.2	T798Q	Pathogenic	0.933
LRP5	O75197-1.2	T798R	Pathogenic	0.867
LRP5	O75197-1.2	T798S	Pathogenic	0.639
LRP5	O75197-1.2	T798V	Pathogenic	0.75
LRP5	O75197-1.2	T798W	Pathogenic	0.91
LRP5	O75197-1.2	T798Y	Pathogenic	0.971
LRP5	O75197-1.2	L799A	Pathogenic	0.899
LRP5	O75197-1.2	L799C	Pathogenic	0.944
LRP5	O75197-1.2	L799D	Pathogenic	0.99
LRP5	O75197-1.2	L799E	Pathogenic	0.974
LRP5	O75197-1.2	L799F	Pathogenic	0.91
LRP5	O75197-1.2	L799G	Pathogenic	0.995
LRP5	O75197-1.2	L799H	Pathogenic	0.987
LRP5	O75197-1.2	L799I	Pathogenic	0.524
LRP5	O75197-1.2	L799K	Pathogenic	0.901
LRP5	O75197-1.2	L799M	Neutral	0.442
LRP5	O75197-1.2	L799N	Pathogenic	0.975
LRP5	O75197-1.2	L799P	Pathogenic	0.992
LRP5	O75197-1.2	L799Q	Pathogenic	0.948
LRP5	O75197-1.2	L799R	Pathogenic	0.898
LRP5	O75197-1.2	L799S	Pathogenic	0.953
LRP5	O75197-1.2	L799T	Pathogenic	0.899
LRP5	O75197-1.2	L799V	Pathogenic	0.698
LRP5	O75197-1.2	L799W	Pathogenic	0.983
LRP5	O75197-1.2	L799Y	Pathogenic	0.945
LRP5	O75197-1.2	V800A	Pathogenic	0.923
LRP5	O75197-1.2	V800C	Pathogenic	0.986
LRP5	O75197-1.2	V800D	Pathogenic	0.993
LRP5	O75197-1.2	V800E	Pathogenic	0.98
LRP5	O75197-1.2	V800F	Pathogenic	0.98
LRP5	O75197-1.2	V800G	Pathogenic	0.996
LRP5	O75197-1.2	V800H	Pathogenic	0.997
LRP5	O75197-1.2	V800I	Neutral	0.368
LRP5	O75197-1.2	V800K	Pathogenic	0.972
LRP5	O75197-1.2	V800L	Pathogenic	0.855
LRP5	O75197-1.2	V800M	Pathogenic	0.9
LRP5	O75197-1.2	V800N	Pathogenic	0.994
LRP5	O75197-1.2	V800P	Pathogenic	0.994
LRP5	O75197-1.2	V800Q	Pathogenic	0.986
LRP5	O75197-1.2	V800R	Pathogenic	0.99
LRP5	O75197-1.2	V800S	Pathogenic	0.988
LRP5	O75197-1.2	V800T	Pathogenic	0.922
LRP5	O75197-1.2	V800W	Pathogenic	0.997
LRP5	O75197-1.2	V800Y	Pathogenic	0.985
LRP5	O75197-1.2	D801A	Neutral	0.309
LRP5	O75197-1.2	D801C	Neutral	0.435
LRP5	O75197-1.2	D801E	Neutral	0.012
LRP5	O75197-1.2	D801F	Neutral	0.26
LRP5	O75197-1.2	D801G	Neutral	0.158
LRP5	O75197-1.2	D801H	Neutral	0.146
LRP5	O75197-1.2	D801I	Neutral	0.261
LRP5	O75197-1.2	D801K	Neutral	0.235
LRP5	O75197-1.2	D801L	Pathogenic	0.54
LRP5	O75197-1.2	D801M	Neutral	0.37
LRP5	O75197-1.2	D801N	Neutral	0.036
LRP5	O75197-1.2	D801P	Neutral	0.096
LRP5	O75197-1.2	D801Q	Neutral	0.072
LRP5	O75197-1.2	D801R	Neutral	0.475
LRP5	O75197-1.2	D801S	Neutral	0.062
LRP5	O75197-1.2	D801T	Neutral	0.138
LRP5	O75197-1.2	D801V	Neutral	0.381
LRP5	O75197-1.2	D801W	Neutral	0.403
LRP5	O75197-1.2	D801Y	Neutral	0.422
LRP5	O75197-1.2	K802A	Neutral	0.289
LRP5	O75197-1.2	K802C	Pathogenic	0.68
LRP5	O75197-1.2	K802D	Pathogenic	0.526
LRP5	O75197-1.2	K802E	Neutral	0.099
LRP5	O75197-1.2	K802F	Pathogenic	0.528
LRP5	O75197-1.2	K802G	Pathogenic	0.613
LRP5	O75197-1.2	K802H	Neutral	0.341
LRP5	O75197-1.2	K802I	Pathogenic	0.52
LRP5	O75197-1.2	K802L	Neutral	0.281
LRP5	O75197-1.2	K802M	Neutral	0.163
LRP5	O75197-1.2	K802N	Neutral	0.24
LRP5	O75197-1.2	K802P	Neutral	0.226
LRP5	O75197-1.2	K802Q	Neutral	0.071
LRP5	O75197-1.2	K802R	Neutral	0.047
LRP5	O75197-1.2	K802S	Neutral	0.155
LRP5	O75197-1.2	K802T	Neutral	0.308
LRP5	O75197-1.2	K802V	Neutral	0.369
LRP5	O75197-1.2	K802W	Neutral	0.414
LRP5	O75197-1.2	K802Y	Neutral	0.433
LRP5	O75197-1.2	V803A	Pathogenic	0.878
LRP5	O75197-1.2	V803C	Pathogenic	0.976
LRP5	O75197-1.2	V803D	Pathogenic	0.988
LRP5	O75197-1.2	V803E	Pathogenic	0.968
LRP5	O75197-1.2	V803F	Pathogenic	0.968
LRP5	O75197-1.2	V803G	Pathogenic	0.993
LRP5	O75197-1.2	V803H	Pathogenic	0.994
LRP5	O75197-1.2	V803I	Neutral	0.26
LRP5	O75197-1.2	V803K	Pathogenic	0.955
LRP5	O75197-1.2	V803L	Pathogenic	0.781
LRP5	O75197-1.2	V803M	Pathogenic	0.844
LRP5	O75197-1.2	V803N	Pathogenic	0.989
LRP5	O75197-1.2	V803P	Pathogenic	0.99
LRP5	O75197-1.2	V803Q	Pathogenic	0.977
LRP5	O75197-1.2	V803R	Pathogenic	0.984
LRP5	O75197-1.2	V803S	Pathogenic	0.98
LRP5	O75197-1.2	V803T	Pathogenic	0.877
LRP5	O75197-1.2	V803W	Pathogenic	0.994
LRP5	O75197-1.2	V803Y	Pathogenic	0.975
LRP5	O75197-1.2	G804A	Pathogenic	0.981
LRP5	O75197-1.2	G804C	Pathogenic	0.999
LRP5	O75197-1.2	G804D	Pathogenic	0.99
LRP5	O75197-1.2	G804E	Pathogenic	0.997
LRP5	O75197-1.2	G804F	Pathogenic	0.997
LRP5	O75197-1.2	G804H	Pathogenic	0.998
LRP5	O75197-1.2	G804I	Pathogenic	0.999
LRP5	O75197-1.2	G804K	Pathogenic	0.996
LRP5	O75197-1.2	G804L	Pathogenic	0.999
LRP5	O75197-1.2	G804M	Pathogenic	0.998
LRP5	O75197-1.2	G804N	Pathogenic	0.975
LRP5	O75197-1.2	G804P	Pathogenic	0.997
LRP5	O75197-1.2	G804Q	Pathogenic	0.998
LRP5	O75197-1.2	G804R	Pathogenic	0.996
LRP5	O75197-1.2	G804S	Pathogenic	0.985
LRP5	O75197-1.2	G804T	Pathogenic	0.998
LRP5	O75197-1.2	G804V	Pathogenic	0.998
LRP5	O75197-1.2	G804W	Pathogenic	0.987
LRP5	O75197-1.2	G804Y	Pathogenic	0.999
LRP5	O75197-1.2	R805A	Pathogenic	0.983
LRP5	O75197-1.2	R805C	Pathogenic	0.997
LRP5	O75197-1.2	R805D	Pathogenic	0.998
LRP5	O75197-1.2	R805E	Pathogenic	0.979
LRP5	O75197-1.2	R805F	Pathogenic	0.994
LRP5	O75197-1.2	R805G	Pathogenic	0.996
LRP5	O75197-1.2	R805H	Pathogenic	0.96
LRP5	O75197-1.2	R805I	Pathogenic	0.994
LRP5	O75197-1.2	R805K	Pathogenic	0.88
LRP5	O75197-1.2	R805L	Pathogenic	0.982
LRP5	O75197-1.2	R805M	Pathogenic	0.965
LRP5	O75197-1.2	R805N	Pathogenic	0.978
LRP5	O75197-1.2	R805P	Pathogenic	0.992
LRP5	O75197-1.2	R805Q	Pathogenic	0.916
LRP5	O75197-1.2	R805S	Pathogenic	0.988
LRP5	O75197-1.2	R805T	Pathogenic	0.984
LRP5	O75197-1.2	R805V	Pathogenic	0.996
LRP5	O75197-1.2	R805W	Pathogenic	0.991
LRP5	O75197-1.2	R805Y	Pathogenic	0.991
LRP5	O75197-1.2	A806C	Pathogenic	0.935
LRP5	O75197-1.2	A806D	Pathogenic	0.989
LRP5	O75197-1.2	A806E	Pathogenic	0.971
LRP5	O75197-1.2	A806F	Pathogenic	0.984
LRP5	O75197-1.2	A806G	Pathogenic	0.953
LRP5	O75197-1.2	A806H	Pathogenic	0.995
LRP5	O75197-1.2	A806I	Pathogenic	0.952
LRP5	O75197-1.2	A806K	Pathogenic	0.959
LRP5	O75197-1.2	A806L	Pathogenic	0.956
LRP5	O75197-1.2	A806M	Pathogenic	0.971
LRP5	O75197-1.2	A806N	Pathogenic	0.991
LRP5	O75197-1.2	A806P	Pathogenic	0.982
LRP5	O75197-1.2	A806Q	Pathogenic	0.98
LRP5	O75197-1.2	A806R	Pathogenic	0.957
LRP5	O75197-1.2	A806S	Pathogenic	0.867
LRP5	O75197-1.2	A806T	Pathogenic	0.961
LRP5	O75197-1.2	A806V	Pathogenic	0.919
LRP5	O75197-1.2	A806W	Pathogenic	0.991
LRP5	O75197-1.2	A806Y	Pathogenic	0.992
LRP5	O75197-1.2	N807A	Pathogenic	0.997
LRP5	O75197-1.2	N807C	Pathogenic	0.998
LRP5	O75197-1.2	N807D	Pathogenic	0.958
LRP5	O75197-1.2	N807E	Pathogenic	0.987
LRP5	O75197-1.2	N807F	Pathogenic	0.996
LRP5	O75197-1.2	N807G	Pathogenic	0.978
LRP5	O75197-1.2	N807H	Pathogenic	0.931
LRP5	O75197-1.2	N807I	Pathogenic	0.996
LRP5	O75197-1.2	N807K	Pathogenic	0.982
LRP5	O75197-1.2	N807L	Pathogenic	0.996
LRP5	O75197-1.2	N807M	Pathogenic	0.993
LRP5	O75197-1.2	N807P	Pathogenic	0.996
LRP5	O75197-1.2	N807Q	Pathogenic	0.983
LRP5	O75197-1.2	N807R	Pathogenic	0.981
LRP5	O75197-1.2	N807S	Pathogenic	0.94
LRP5	O75197-1.2	N807T	Pathogenic	0.974
LRP5	O75197-1.2	N807V	Pathogenic	0.998
LRP5	O75197-1.2	N807W	Pathogenic	0.998
LRP5	O75197-1.2	N807Y	Pathogenic	0.994
LRP5	O75197-1.2	D808A	Pathogenic	0.853
LRP5	O75197-1.2	D808C	Pathogenic	0.909
LRP5	O75197-1.2	D808E	Neutral	0.138
LRP5	O75197-1.2	D808F	Pathogenic	0.82
LRP5	O75197-1.2	D808G	Pathogenic	0.709
LRP5	O75197-1.2	D808H	Pathogenic	0.69
LRP5	O75197-1.2	D808I	Pathogenic	0.821
LRP5	O75197-1.2	D808K	Pathogenic	0.799
LRP5	O75197-1.2	D808L	Pathogenic	0.939
LRP5	O75197-1.2	D808M	Pathogenic	0.884
LRP5	O75197-1.2	D808N	Neutral	0.324
LRP5	O75197-1.2	D808P	Pathogenic	0.579
LRP5	O75197-1.2	D808Q	Pathogenic	0.502
LRP5	O75197-1.2	D808R	Pathogenic	0.921
LRP5	O75197-1.2	D808S	Neutral	0.463
LRP5	O75197-1.2	D808T	Pathogenic	0.675
LRP5	O75197-1.2	D808V	Pathogenic	0.889
LRP5	O75197-1.2	D808W	Pathogenic	0.898
LRP5	O75197-1.2	D808Y	Pathogenic	0.904
LRP5	O75197-1.2	L809A	Pathogenic	0.981
LRP5	O75197-1.2	L809C	Pathogenic	0.99
LRP5	O75197-1.2	L809D	Pathogenic	0.998
LRP5	O75197-1.2	L809E	Pathogenic	0.995
LRP5	O75197-1.2	L809F	Pathogenic	0.983
LRP5	O75197-1.2	L809G	Pathogenic	0.999
LRP5	O75197-1.2	L809H	Pathogenic	0.998
LRP5	O75197-1.2	L809I	Pathogenic	0.862
LRP5	O75197-1.2	L809K	Pathogenic	0.981
LRP5	O75197-1.2	L809M	Pathogenic	0.818
LRP5	O75197-1.2	L809N	Pathogenic	0.995
LRP5	O75197-1.2	L809P	Pathogenic	0.999
LRP5	O75197-1.2	L809Q	Pathogenic	0.99
LRP5	O75197-1.2	L809R	Pathogenic	0.98
LRP5	O75197-1.2	L809S	Pathogenic	0.991
LRP5	O75197-1.2	L809T	Pathogenic	0.98
LRP5	O75197-1.2	L809V	Pathogenic	0.929
LRP5	O75197-1.2	L809W	Pathogenic	0.997
LRP5	O75197-1.2	L809Y	Pathogenic	0.99
LRP5	O75197-1.2	T810A	Pathogenic	0.985
LRP5	O75197-1.2	T810C	Pathogenic	0.991
LRP5	O75197-1.2	T810D	Pathogenic	0.989
LRP5	O75197-1.2	T810E	Pathogenic	0.99
LRP5	O75197-1.2	T810F	Pathogenic	0.994
LRP5	O75197-1.2	T810G	Pathogenic	0.998
LRP5	O75197-1.2	T810H	Pathogenic	0.998
LRP5	O75197-1.2	T810I	Pathogenic	0.982
LRP5	O75197-1.2	T810K	Pathogenic	0.986
LRP5	O75197-1.2	T810L	Pathogenic	0.983
LRP5	O75197-1.2	T810M	Pathogenic	0.989
LRP5	O75197-1.2	T810N	Pathogenic	0.971
LRP5	O75197-1.2	T810P	Pathogenic	0.993
LRP5	O75197-1.2	T810Q	Pathogenic	0.993
LRP5	O75197-1.2	T810R	Pathogenic	0.985
LRP5	O75197-1.2	T810S	Pathogenic	0.947
LRP5	O75197-1.2	T810V	Pathogenic	0.968
LRP5	O75197-1.2	T810W	Pathogenic	0.99
LRP5	O75197-1.2	T810Y	Pathogenic	0.997
LRP5	O75197-1.2	I811A	Pathogenic	0.981
LRP5	O75197-1.2	I811C	Pathogenic	0.99
LRP5	O75197-1.2	I811D	Pathogenic	0.995
LRP5	O75197-1.2	I811E	Pathogenic	0.995
LRP5	O75197-1.2	I811F	Pathogenic	0.986
LRP5	O75197-1.2	I811G	Pathogenic	0.999
LRP5	O75197-1.2	I811H	Pathogenic	0.998
LRP5	O75197-1.2	I811K	Pathogenic	0.994
LRP5	O75197-1.2	I811L	Pathogenic	0.875
LRP5	O75197-1.2	I811M	Pathogenic	0.933
LRP5	O75197-1.2	I811N	Pathogenic	0.996
LRP5	O75197-1.2	I811P	Pathogenic	0.999
LRP5	O75197-1.2	I811Q	Pathogenic	0.997
LRP5	O75197-1.2	I811R	Pathogenic	0.994
LRP5	O75197-1.2	I811S	Pathogenic	0.991
LRP5	O75197-1.2	I811T	Pathogenic	0.981
LRP5	O75197-1.2	I811V	Pathogenic	0.591
LRP5	O75197-1.2	I811W	Pathogenic	0.999
LRP5	O75197-1.2	I811Y	Pathogenic	0.99
LRP5	O75197-1.2	D812A	Pathogenic	0.997
LRP5	O75197-1.2	D812C	Pathogenic	0.998
LRP5	O75197-1.2	D812E	Pathogenic	0.907
LRP5	O75197-1.2	D812F	Pathogenic	0.996
LRP5	O75197-1.2	D812G	Pathogenic	0.993
LRP5	O75197-1.2	D812H	Pathogenic	0.993
LRP5	O75197-1.2	D812I	Pathogenic	0.996
LRP5	O75197-1.2	D812K	Pathogenic	0.996
LRP5	O75197-1.2	D812L	Pathogenic	0.999
LRP5	O75197-1.2	D812M	Pathogenic	0.998
LRP5	O75197-1.2	D812N	Pathogenic	0.967
LRP5	O75197-1.2	D812P	Pathogenic	0.988
LRP5	O75197-1.2	D812Q	Pathogenic	0.984
LRP5	O75197-1.2	D812R	Pathogenic	0.999
LRP5	O75197-1.2	D812S	Pathogenic	0.981
LRP5	O75197-1.2	D812T	Pathogenic	0.992
LRP5	O75197-1.2	D812V	Pathogenic	0.998
LRP5	O75197-1.2	D812W	Pathogenic	0.998
LRP5	O75197-1.2	D812Y	Pathogenic	0.998
LRP5	O75197-1.2	Y813A	Pathogenic	0.996
LRP5	O75197-1.2	Y813C	Pathogenic	0.998
LRP5	O75197-1.2	Y813D	Pathogenic	0.997
LRP5	O75197-1.2	Y813E	Pathogenic	0.991
LRP5	O75197-1.2	Y813F	Neutral	0.478
LRP5	O75197-1.2	Y813G	Pathogenic	0.998
LRP5	O75197-1.2	Y813H	Pathogenic	0.731
LRP5	O75197-1.2	Y813I	Pathogenic	0.987
LRP5	O75197-1.2	Y813K	Pathogenic	0.989
LRP5	O75197-1.2	Y813L	Pathogenic	0.988
LRP5	O75197-1.2	Y813M	Pathogenic	0.992
LRP5	O75197-1.2	Y813N	Pathogenic	0.991
LRP5	O75197-1.2	Y813P	Pathogenic	0.999
LRP5	O75197-1.2	Y813Q	Pathogenic	0.982
LRP5	O75197-1.2	Y813R	Pathogenic	0.989
LRP5	O75197-1.2	Y813S	Pathogenic	0.995
LRP5	O75197-1.2	Y813T	Pathogenic	0.996
LRP5	O75197-1.2	Y813V	Pathogenic	0.992
LRP5	O75197-1.2	Y813W	Pathogenic	0.643
LRP5	O75197-1.2	A814C	Neutral	0.277
LRP5	O75197-1.2	A814D	Pathogenic	0.71
LRP5	O75197-1.2	A814E	Neutral	0.468
LRP5	O75197-1.2	A814F	Pathogenic	0.614
LRP5	O75197-1.2	A814G	Neutral	0.347
LRP5	O75197-1.2	A814H	Pathogenic	0.84
LRP5	O75197-1.2	A814I	Neutral	0.345
LRP5	O75197-1.2	A814K	Neutral	0.382
LRP5	O75197-1.2	A814L	Neutral	0.366
LRP5	O75197-1.2	A814M	Neutral	0.467
LRP5	O75197-1.2	A814N	Pathogenic	0.739
LRP5	O75197-1.2	A814P	Pathogenic	0.594
LRP5	O75197-1.2	A814Q	Pathogenic	0.559
LRP5	O75197-1.2	A814R	Neutral	0.374
LRP5	O75197-1.2	A814S	Neutral	0.147
LRP5	O75197-1.2	A814T	Neutral	0.398
LRP5	O75197-1.2	A814V	Neutral	0.231
LRP5	O75197-1.2	A814W	Pathogenic	0.754
LRP5	O75197-1.2	A814Y	Pathogenic	0.768
LRP5	O75197-1.2	D815A	Neutral	0.325
LRP5	O75197-1.2	D815C	Neutral	0.453
LRP5	O75197-1.2	D815E	Neutral	0.013
LRP5	O75197-1.2	D815F	Neutral	0.274
LRP5	O75197-1.2	D815G	Neutral	0.168
LRP5	O75197-1.2	D815H	Neutral	0.156
LRP5	O75197-1.2	D815I	Neutral	0.275
LRP5	O75197-1.2	D815K	Neutral	0.248
LRP5	O75197-1.2	D815L	Pathogenic	0.559
LRP5	O75197-1.2	D815M	Neutral	0.388
LRP5	O75197-1.2	D815N	Neutral	0.038
LRP5	O75197-1.2	D815P	Neutral	0.102
LRP5	O75197-1.2	D815Q	Neutral	0.077
LRP5	O75197-1.2	D815R	Neutral	0.493
LRP5	O75197-1.2	D815S	Neutral	0.067
LRP5	O75197-1.2	D815T	Neutral	0.147
LRP5	O75197-1.2	D815V	Neutral	0.398
LRP5	O75197-1.2	D815W	Neutral	0.421
LRP5	O75197-1.2	D815Y	Neutral	0.44
LRP5	O75197-1.2	Q816A	Pathogenic	0.64
LRP5	O75197-1.2	Q816C	Pathogenic	0.903
LRP5	O75197-1.2	Q816D	Neutral	0.374
LRP5	O75197-1.2	Q816E	Neutral	0.069
LRP5	O75197-1.2	Q816F	Pathogenic	0.82
LRP5	O75197-1.2	Q816G	Pathogenic	0.874
LRP5	O75197-1.2	Q816H	Neutral	0.423
LRP5	O75197-1.2	Q816I	Pathogenic	0.821
LRP5	O75197-1.2	Q816K	Neutral	0.139
LRP5	O75197-1.2	Q816L	Pathogenic	0.623
LRP5	O75197-1.2	Q816M	Neutral	0.214
LRP5	O75197-1.2	Q816N	Neutral	0.411
LRP5	O75197-1.2	Q816P	Pathogenic	0.561
LRP5	O75197-1.2	Q816R	Neutral	0.135
LRP5	O75197-1.2	Q816S	Neutral	0.446
LRP5	O75197-1.2	Q816T	Pathogenic	0.66
LRP5	O75197-1.2	Q816V	Pathogenic	0.719
LRP5	O75197-1.2	Q816W	Neutral	0.487
LRP5	O75197-1.2	Q816Y	Pathogenic	0.506
LRP5	O75197-1.2	R817A	Pathogenic	0.953
LRP5	O75197-1.2	R817C	Pathogenic	0.991
LRP5	O75197-1.2	R817D	Pathogenic	0.994
LRP5	O75197-1.2	R817E	Pathogenic	0.944
LRP5	O75197-1.2	R817F	Pathogenic	0.982
LRP5	O75197-1.2	R817G	Pathogenic	0.988
LRP5	O75197-1.2	R817H	Pathogenic	0.895
LRP5	O75197-1.2	R817I	Pathogenic	0.982
LRP5	O75197-1.2	R817K	Pathogenic	0.721
LRP5	O75197-1.2	R817L	Pathogenic	0.951
LRP5	O75197-1.2	R817M	Pathogenic	0.907
LRP5	O75197-1.2	R817N	Pathogenic	0.941
LRP5	O75197-1.2	R817P	Pathogenic	0.978
LRP5	O75197-1.2	R817Q	Pathogenic	0.792
LRP5	O75197-1.2	R817S	Pathogenic	0.966
LRP5	O75197-1.2	R817T	Pathogenic	0.957
LRP5	O75197-1.2	R817V	Pathogenic	0.989
LRP5	O75197-1.2	R817W	Pathogenic	0.974
LRP5	O75197-1.2	R817Y	Pathogenic	0.975
LRP5	O75197-1.2	L818A	Pathogenic	0.98
LRP5	O75197-1.2	L818C	Pathogenic	0.989
LRP5	O75197-1.2	L818D	Pathogenic	0.998
LRP5	O75197-1.2	L818E	Pathogenic	0.995
LRP5	O75197-1.2	L818F	Pathogenic	0.982
LRP5	O75197-1.2	L818G	Pathogenic	0.999
LRP5	O75197-1.2	L818H	Pathogenic	0.998
LRP5	O75197-1.2	L818I	Pathogenic	0.858
LRP5	O75197-1.2	L818K	Pathogenic	0.981
LRP5	O75197-1.2	L818M	Pathogenic	0.814
LRP5	O75197-1.2	L818N	Pathogenic	0.995
LRP5	O75197-1.2	L818P	Pathogenic	0.999
LRP5	O75197-1.2	L818Q	Pathogenic	0.99
LRP5	O75197-1.2	L818R	Pathogenic	0.98
LRP5	O75197-1.2	L818S	Pathogenic	0.991
LRP5	O75197-1.2	L818T	Pathogenic	0.98
LRP5	O75197-1.2	L818V	Pathogenic	0.927
LRP5	O75197-1.2	L818W	Pathogenic	0.997
LRP5	O75197-1.2	L818Y	Pathogenic	0.989
LRP5	O75197-1.2	Y819A	Pathogenic	0.999
LRP5	O75197-1.2	Y819C	Pathogenic	0.999
LRP5	O75197-1.2	Y819D	Pathogenic	0.999
LRP5	O75197-1.2	Y819E	Pathogenic	0.997
LRP5	O75197-1.2	Y819F	Pathogenic	0.756
LRP5	O75197-1.2	Y819G	Pathogenic	0.999
LRP5	O75197-1.2	Y819H	Pathogenic	0.901
LRP5	O75197-1.2	Y819I	Pathogenic	0.996
LRP5	O75197-1.2	Y819K	Pathogenic	0.997
LRP5	O75197-1.2	Y819L	Pathogenic	0.996
LRP5	O75197-1.2	Y819M	Pathogenic	0.998
LRP5	O75197-1.2	Y819N	Pathogenic	0.997
LRP5	O75197-1.2	Y819P	Pathogenic	1.0
LRP5	O75197-1.2	Y819Q	Pathogenic	0.995
LRP5	O75197-1.2	Y819R	Pathogenic	0.997
LRP5	O75197-1.2	Y819S	Pathogenic	0.998
LRP5	O75197-1.2	Y819T	Pathogenic	0.999
LRP5	O75197-1.2	Y819V	Pathogenic	0.998
LRP5	O75197-1.2	Y819W	Pathogenic	0.858
LRP5	O75197-1.2	W820A	Pathogenic	1.0
LRP5	O75197-1.2	W820C	Pathogenic	0.999
LRP5	O75197-1.2	W820D	Pathogenic	1.0
LRP5	O75197-1.2	W820E	Pathogenic	0.999
LRP5	O75197-1.2	W820F	Pathogenic	0.991
LRP5	O75197-1.2	W820G	Pathogenic	0.998
LRP5	O75197-1.2	W820H	Pathogenic	0.999
LRP5	O75197-1.2	W820I	Pathogenic	1.0
LRP5	O75197-1.2	W820K	Pathogenic	0.999
LRP5	O75197-1.2	W820L	Pathogenic	1.0
LRP5	O75197-1.2	W820M	Pathogenic	0.998
LRP5	O75197-1.2	W820N	Pathogenic	1.0
LRP5	O75197-1.2	W820P	Pathogenic	1.0
LRP5	O75197-1.2	W820Q	Pathogenic	0.998
LRP5	O75197-1.2	W820R	Pathogenic	0.999
LRP5	O75197-1.2	W820S	Pathogenic	0.999
LRP5	O75197-1.2	W820T	Pathogenic	0.999
LRP5	O75197-1.2	W820V	Pathogenic	1.0
LRP5	O75197-1.2	W820Y	Pathogenic	0.945
LRP5	O75197-1.2	T821A	Pathogenic	0.94
LRP5	O75197-1.2	T821C	Pathogenic	0.964
LRP5	O75197-1.2	T821D	Pathogenic	0.954
LRP5	O75197-1.2	T821E	Pathogenic	0.958
LRP5	O75197-1.2	T821F	Pathogenic	0.974
LRP5	O75197-1.2	T821G	Pathogenic	0.991
LRP5	O75197-1.2	T821H	Pathogenic	0.993
LRP5	O75197-1.2	T821I	Pathogenic	0.925
LRP5	O75197-1.2	T821K	Pathogenic	0.941
LRP5	O75197-1.2	T821L	Pathogenic	0.931
LRP5	O75197-1.2	T821M	Pathogenic	0.954
LRP5	O75197-1.2	T821N	Pathogenic	0.887
LRP5	O75197-1.2	T821P	Pathogenic	0.971
LRP5	O75197-1.2	T821Q	Pathogenic	0.97
LRP5	O75197-1.2	T821R	Pathogenic	0.939
LRP5	O75197-1.2	T821S	Pathogenic	0.806
LRP5	O75197-1.2	T821V	Pathogenic	0.876
LRP5	O75197-1.2	T821W	Pathogenic	0.959
LRP5	O75197-1.2	T821Y	Pathogenic	0.987
LRP5	O75197-1.2	D822A	Pathogenic	0.994
LRP5	O75197-1.2	D822C	Pathogenic	0.996
LRP5	O75197-1.2	D822E	Pathogenic	0.811
LRP5	O75197-1.2	D822F	Pathogenic	0.992
LRP5	O75197-1.2	D822G	Pathogenic	0.985
LRP5	O75197-1.2	D822H	Pathogenic	0.984
LRP5	O75197-1.2	D822I	Pathogenic	0.992
LRP5	O75197-1.2	D822K	Pathogenic	0.991
LRP5	O75197-1.2	D822L	Pathogenic	0.998
LRP5	O75197-1.2	D822M	Pathogenic	0.995
LRP5	O75197-1.2	D822N	Pathogenic	0.928
LRP5	O75197-1.2	D822P	Pathogenic	0.974
LRP5	O75197-1.2	D822Q	Pathogenic	0.964
LRP5	O75197-1.2	D822R	Pathogenic	0.997
LRP5	O75197-1.2	D822S	Pathogenic	0.959
LRP5	O75197-1.2	D822T	Pathogenic	0.982
LRP5	O75197-1.2	D822V	Pathogenic	0.995
LRP5	O75197-1.2	D822W	Pathogenic	0.996
LRP5	O75197-1.2	D822Y	Pathogenic	0.996
LRP5	O75197-1.2	L823A	Pathogenic	0.888
LRP5	O75197-1.2	L823C	Pathogenic	0.937
LRP5	O75197-1.2	L823D	Pathogenic	0.989
LRP5	O75197-1.2	L823E	Pathogenic	0.971
LRP5	O75197-1.2	L823F	Pathogenic	0.9
LRP5	O75197-1.2	L823G	Pathogenic	0.994
LRP5	O75197-1.2	L823H	Pathogenic	0.986
LRP5	O75197-1.2	L823I	Neutral	0.494
LRP5	O75197-1.2	L823K	Pathogenic	0.89
LRP5	O75197-1.2	L823M	Neutral	0.413
LRP5	O75197-1.2	L823N	Pathogenic	0.971
LRP5	O75197-1.2	L823P	Pathogenic	0.991
LRP5	O75197-1.2	L823Q	Pathogenic	0.942
LRP5	O75197-1.2	L823R	Pathogenic	0.887
LRP5	O75197-1.2	L823S	Pathogenic	0.947
LRP5	O75197-1.2	L823T	Pathogenic	0.888
LRP5	O75197-1.2	L823V	Pathogenic	0.672
LRP5	O75197-1.2	L823W	Pathogenic	0.981
LRP5	O75197-1.2	L823Y	Pathogenic	0.938
LRP5	O75197-1.2	D824A	Pathogenic	0.966
LRP5	O75197-1.2	D824C	Pathogenic	0.98
LRP5	O75197-1.2	D824E	Neutral	0.442
LRP5	O75197-1.2	D824F	Pathogenic	0.958
LRP5	O75197-1.2	D824G	Pathogenic	0.924
LRP5	O75197-1.2	D824H	Pathogenic	0.917
LRP5	O75197-1.2	D824I	Pathogenic	0.958
LRP5	O75197-1.2	D824K	Pathogenic	0.952
LRP5	O75197-1.2	D824L	Pathogenic	0.987
LRP5	O75197-1.2	D824M	Pathogenic	0.974
LRP5	O75197-1.2	D824N	Pathogenic	0.704
LRP5	O75197-1.2	D824P	Pathogenic	0.872
LRP5	O75197-1.2	D824Q	Pathogenic	0.833
LRP5	O75197-1.2	D824R	Pathogenic	0.983
LRP5	O75197-1.2	D824S	Pathogenic	0.81
LRP5	O75197-1.2	D824T	Pathogenic	0.911
LRP5	O75197-1.2	D824V	Pathogenic	0.975
LRP5	O75197-1.2	D824W	Pathogenic	0.977
LRP5	O75197-1.2	D824Y	Pathogenic	0.979
LRP5	O75197-1.2	T825A	Pathogenic	0.911
LRP5	O75197-1.2	T825C	Pathogenic	0.946
LRP5	O75197-1.2	T825D	Pathogenic	0.932
LRP5	O75197-1.2	T825E	Pathogenic	0.937
LRP5	O75197-1.2	T825F	Pathogenic	0.961
LRP5	O75197-1.2	T825G	Pathogenic	0.987
LRP5	O75197-1.2	T825H	Pathogenic	0.989
LRP5	O75197-1.2	T825I	Pathogenic	0.891
LRP5	O75197-1.2	T825K	Pathogenic	0.913
LRP5	O75197-1.2	T825L	Pathogenic	0.899
LRP5	O75197-1.2	T825M	Pathogenic	0.932
LRP5	O75197-1.2	T825N	Pathogenic	0.839
LRP5	O75197-1.2	T825P	Pathogenic	0.957
LRP5	O75197-1.2	T825Q	Pathogenic	0.956
LRP5	O75197-1.2	T825R	Pathogenic	0.91
LRP5	O75197-1.2	T825S	Pathogenic	0.733
LRP5	O75197-1.2	T825V	Pathogenic	0.824
LRP5	O75197-1.2	T825W	Pathogenic	0.94
LRP5	O75197-1.2	T825Y	Pathogenic	0.981
LRP5	O75197-1.2	N826A	Neutral	0.464
LRP5	O75197-1.2	N826C	Pathogenic	0.598
LRP5	O75197-1.2	N826D	Neutral	0.058
LRP5	O75197-1.2	N826E	Neutral	0.173
LRP5	O75197-1.2	N826F	Neutral	0.408
LRP5	O75197-1.2	N826G	Neutral	0.107
LRP5	O75197-1.2	N826H	Neutral	0.035
LRP5	O75197-1.2	N826I	Neutral	0.409
LRP5	O75197-1.2	N826K	Neutral	0.128
LRP5	O75197-1.2	N826L	Neutral	0.431
LRP5	O75197-1.2	N826M	Neutral	0.275
LRP5	O75197-1.2	N826P	Neutral	0.384
LRP5	O75197-1.2	N826Q	Neutral	0.132
LRP5	O75197-1.2	N826R	Neutral	0.124
LRP5	O75197-1.2	N826S	Neutral	0.041
LRP5	O75197-1.2	N826T	Neutral	0.093
LRP5	O75197-1.2	N826V	Pathogenic	0.547
LRP5	O75197-1.2	N826W	Pathogenic	0.57
LRP5	O75197-1.2	N826Y	Neutral	0.32
LRP5	O75197-1.2	M827A	Pathogenic	0.539
LRP5	O75197-1.2	M827C	Pathogenic	0.688
LRP5	O75197-1.2	M827D	Pathogenic	0.811
LRP5	O75197-1.2	M827E	Pathogenic	0.62
LRP5	O75197-1.2	M827F	Neutral	0.365
LRP5	O75197-1.2	M827G	Pathogenic	0.889
LRP5	O75197-1.2	M827H	Pathogenic	0.767
LRP5	O75197-1.2	M827I	Neutral	0.159
LRP5	O75197-1.2	M827K	Neutral	0.283
LRP5	O75197-1.2	M827L	Neutral	0.064
LRP5	O75197-1.2	M827N	Pathogenic	0.623
LRP5	O75197-1.2	M827P	Pathogenic	0.842
LRP5	O75197-1.2	M827Q	Neutral	0.206
LRP5	O75197-1.2	M827R	Neutral	0.276
LRP5	O75197-1.2	M827S	Neutral	0.465
LRP5	O75197-1.2	M827T	Pathogenic	0.538
LRP5	O75197-1.2	M827V	Neutral	0.232
LRP5	O75197-1.2	M827W	Pathogenic	0.525
LRP5	O75197-1.2	M827Y	Pathogenic	0.691
LRP5	O75197-1.2	I828A	Pathogenic	0.988
LRP5	O75197-1.2	I828C	Pathogenic	0.994
LRP5	O75197-1.2	I828D	Pathogenic	0.997
LRP5	O75197-1.2	I828E	Pathogenic	0.997
LRP5	O75197-1.2	I828F	Pathogenic	0.991
LRP5	O75197-1.2	I828G	Pathogenic	0.999
LRP5	O75197-1.2	I828H	Pathogenic	0.999
LRP5	O75197-1.2	I828K	Pathogenic	0.996
LRP5	O75197-1.2	I828L	Pathogenic	0.918
LRP5	O75197-1.2	I828M	Pathogenic	0.957
LRP5	O75197-1.2	I828N	Pathogenic	0.997
LRP5	O75197-1.2	I828P	Pathogenic	0.999
LRP5	O75197-1.2	I828Q	Pathogenic	0.998
LRP5	O75197-1.2	I828R	Pathogenic	0.996
LRP5	O75197-1.2	I828S	Pathogenic	0.995
LRP5	O75197-1.2	I828T	Pathogenic	0.988
LRP5	O75197-1.2	I828V	Pathogenic	0.698
LRP5	O75197-1.2	I828W	Pathogenic	1.0
LRP5	O75197-1.2	I828Y	Pathogenic	0.994
LRP5	O75197-1.2	E829A	Pathogenic	0.971
LRP5	O75197-1.2	E829C	Pathogenic	0.998
LRP5	O75197-1.2	E829D	Pathogenic	0.718
LRP5	O75197-1.2	E829F	Pathogenic	0.988
LRP5	O75197-1.2	E829G	Pathogenic	0.992
LRP5	O75197-1.2	E829H	Pathogenic	0.931
LRP5	O75197-1.2	E829I	Pathogenic	0.988
LRP5	O75197-1.2	E829K	Pathogenic	0.863
LRP5	O75197-1.2	E829L	Pathogenic	0.989
LRP5	O75197-1.2	E829M	Pathogenic	0.979
LRP5	O75197-1.2	E829N	Pathogenic	0.963
LRP5	O75197-1.2	E829P	Pathogenic	0.96
LRP5	O75197-1.2	E829Q	Pathogenic	0.668
LRP5	O75197-1.2	E829R	Pathogenic	0.949
LRP5	O75197-1.2	E829S	Pathogenic	0.938
LRP5	O75197-1.2	E829T	Pathogenic	0.973
LRP5	O75197-1.2	E829V	Pathogenic	0.98
LRP5	O75197-1.2	E829W	Pathogenic	0.982
LRP5	O75197-1.2	E829Y	Pathogenic	0.983
LRP5	O75197-1.2	S830A	Pathogenic	0.871
LRP5	O75197-1.2	S830C	Pathogenic	0.971
LRP5	O75197-1.2	S830D	Pathogenic	0.935
LRP5	O75197-1.2	S830E	Pathogenic	0.94
LRP5	O75197-1.2	S830F	Pathogenic	0.979
LRP5	O75197-1.2	S830G	Pathogenic	0.963
LRP5	O75197-1.2	S830H	Pathogenic	0.986
LRP5	O75197-1.2	S830I	Pathogenic	0.979
LRP5	O75197-1.2	S830K	Pathogenic	0.916
LRP5	O75197-1.2	S830L	Pathogenic	0.981
LRP5	O75197-1.2	S830M	Pathogenic	0.962
LRP5	O75197-1.2	S830N	Pathogenic	0.844
LRP5	O75197-1.2	S830P	Pathogenic	0.977
LRP5	O75197-1.2	S830Q	Pathogenic	0.957
LRP5	O75197-1.2	S830R	Pathogenic	0.97
LRP5	O75197-1.2	S830T	Pathogenic	0.874
LRP5	O75197-1.2	S830V	Pathogenic	0.988
LRP5	O75197-1.2	S830W	Pathogenic	0.989
LRP5	O75197-1.2	S830Y	Pathogenic	0.99
LRP5	O75197-1.2	S831A	Neutral	0.31
LRP5	O75197-1.2	S831C	Pathogenic	0.693
LRP5	O75197-1.2	S831D	Neutral	0.487
LRP5	O75197-1.2	S831E	Pathogenic	0.509
LRP5	O75197-1.2	S831F	Pathogenic	0.755
LRP5	O75197-1.2	S831G	Pathogenic	0.636
LRP5	O75197-1.2	S831H	Pathogenic	0.821
LRP5	O75197-1.2	S831I	Pathogenic	0.756
LRP5	O75197-1.2	S831K	Neutral	0.421
LRP5	O75197-1.2	S831L	Pathogenic	0.772
LRP5	O75197-1.2	S831M	Pathogenic	0.629
LRP5	O75197-1.2	S831N	Neutral	0.265
LRP5	O75197-1.2	S831P	Pathogenic	0.739
LRP5	O75197-1.2	S831Q	Pathogenic	0.599
LRP5	O75197-1.2	S831R	Pathogenic	0.681
LRP5	O75197-1.2	S831T	Neutral	0.315
LRP5	O75197-1.2	S831V	Pathogenic	0.844
LRP5	O75197-1.2	S831W	Pathogenic	0.856
LRP5	O75197-1.2	S831Y	Pathogenic	0.865
LRP5	O75197-1.2	N832A	Pathogenic	0.986
LRP5	O75197-1.2	N832C	Pathogenic	0.992
LRP5	O75197-1.2	N832D	Pathogenic	0.83
LRP5	O75197-1.2	N832E	Pathogenic	0.943
LRP5	O75197-1.2	N832F	Pathogenic	0.982
LRP5	O75197-1.2	N832G	Pathogenic	0.904
LRP5	O75197-1.2	N832H	Pathogenic	0.741
LRP5	O75197-1.2	N832I	Pathogenic	0.982
LRP5	O75197-1.2	N832K	Pathogenic	0.92
LRP5	O75197-1.2	N832L	Pathogenic	0.984
LRP5	O75197-1.2	N832M	Pathogenic	0.968
LRP5	O75197-1.2	N832P	Pathogenic	0.98
LRP5	O75197-1.2	N832Q	Pathogenic	0.923
LRP5	O75197-1.2	N832R	Pathogenic	0.918
LRP5	O75197-1.2	N832S	Pathogenic	0.769
LRP5	O75197-1.2	N832T	Pathogenic	0.889
LRP5	O75197-1.2	N832V	Pathogenic	0.99
LRP5	O75197-1.2	N832W	Pathogenic	0.991
LRP5	O75197-1.2	N832Y	Pathogenic	0.974
LRP5	O75197-1.2	M833A	Pathogenic	0.991
LRP5	O75197-1.2	M833C	Pathogenic	0.995
LRP5	O75197-1.2	M833D	Pathogenic	0.998
LRP5	O75197-1.2	M833E	Pathogenic	0.994
LRP5	O75197-1.2	M833F	Pathogenic	0.982
LRP5	O75197-1.2	M833G	Pathogenic	0.999
LRP5	O75197-1.2	M833H	Pathogenic	0.997
LRP5	O75197-1.2	M833I	Pathogenic	0.947
LRP5	O75197-1.2	M833K	Pathogenic	0.974
LRP5	O75197-1.2	M833L	Pathogenic	0.866
LRP5	O75197-1.2	M833N	Pathogenic	0.994
LRP5	O75197-1.2	M833P	Pathogenic	0.998
LRP5	O75197-1.2	M833Q	Pathogenic	0.961
LRP5	O75197-1.2	M833R	Pathogenic	0.973
LRP5	O75197-1.2	M833S	Pathogenic	0.988
LRP5	O75197-1.2	M833T	Pathogenic	0.991
LRP5	O75197-1.2	M833V	Pathogenic	0.966
LRP5	O75197-1.2	M833W	Pathogenic	0.991
LRP5	O75197-1.2	M833Y	Pathogenic	0.995
LRP5	O75197-1.2	L834A	Neutral	0.493
LRP5	O75197-1.2	L834C	Pathogenic	0.647
LRP5	O75197-1.2	L834D	Pathogenic	0.916
LRP5	O75197-1.2	L834E	Pathogenic	0.805
LRP5	O75197-1.2	L834F	Pathogenic	0.525
LRP5	O75197-1.2	L834G	Pathogenic	0.953
LRP5	O75197-1.2	L834H	Pathogenic	0.893
LRP5	O75197-1.2	L834I	Neutral	0.107
LRP5	O75197-1.2	L834K	Neutral	0.499
LRP5	O75197-1.2	L834M	Neutral	0.08
LRP5	O75197-1.2	L834N	Pathogenic	0.807
LRP5	O75197-1.2	L834P	Pathogenic	0.931
LRP5	O75197-1.2	L834Q	Pathogenic	0.665
LRP5	O75197-1.2	L834R	Neutral	0.491
LRP5	O75197-1.2	L834S	Pathogenic	0.687
LRP5	O75197-1.2	L834T	Neutral	0.492
LRP5	O75197-1.2	L834V	Neutral	0.201
LRP5	O75197-1.2	L834W	Pathogenic	0.866
LRP5	O75197-1.2	L834Y	Pathogenic	0.65
LRP5	O75197-1.2	G835A	Pathogenic	0.956
LRP5	O75197-1.2	G835C	Pathogenic	0.997
LRP5	O75197-1.2	G835D	Pathogenic	0.977
LRP5	O75197-1.2	G835E	Pathogenic	0.993
LRP5	O75197-1.2	G835F	Pathogenic	0.993
LRP5	O75197-1.2	G835H	Pathogenic	0.995
LRP5	O75197-1.2	G835I	Pathogenic	0.998
LRP5	O75197-1.2	G835K	Pathogenic	0.99
LRP5	O75197-1.2	G835L	Pathogenic	0.998
LRP5	O75197-1.2	G835M	Pathogenic	0.996
LRP5	O75197-1.2	G835N	Pathogenic	0.941
LRP5	O75197-1.2	G835P	Pathogenic	0.993
LRP5	O75197-1.2	G835Q	Pathogenic	0.995
LRP5	O75197-1.2	G835R	Pathogenic	0.99
LRP5	O75197-1.2	G835S	Pathogenic	0.965
LRP5	O75197-1.2	G835T	Pathogenic	0.995
LRP5	O75197-1.2	G835V	Pathogenic	0.996
LRP5	O75197-1.2	G835W	Pathogenic	0.968
LRP5	O75197-1.2	G835Y	Pathogenic	0.997
LRP5	O75197-1.2	Q836A	Neutral	0.385
LRP5	O75197-1.2	Q836C	Pathogenic	0.765
LRP5	O75197-1.2	Q836D	Neutral	0.173
LRP5	O75197-1.2	Q836E	Neutral	0.026
LRP5	O75197-1.2	Q836F	Pathogenic	0.616
LRP5	O75197-1.2	Q836G	Pathogenic	0.708
LRP5	O75197-1.2	Q836H	Neutral	0.205
LRP5	O75197-1.2	Q836I	Pathogenic	0.617
LRP5	O75197-1.2	Q836K	Neutral	0.054
LRP5	O75197-1.2	Q836L	Neutral	0.367
LRP5	O75197-1.2	Q836M	Neutral	0.087
LRP5	O75197-1.2	Q836N	Neutral	0.197
LRP5	O75197-1.2	Q836P	Neutral	0.31
LRP5	O75197-1.2	Q836R	Neutral	0.052
LRP5	O75197-1.2	Q836S	Neutral	0.22
LRP5	O75197-1.2	Q836T	Neutral	0.406
LRP5	O75197-1.2	Q836V	Neutral	0.473
LRP5	O75197-1.2	Q836W	Neutral	0.25
LRP5	O75197-1.2	Q836Y	Neutral	0.265
LRP5	O75197-1.2	E837A	Neutral	0.055
LRP5	O75197-1.2	E837C	Neutral	0.482
LRP5	O75197-1.2	E837D	Neutral	0.004
LRP5	O75197-1.2	E837F	Neutral	0.129
LRP5	O75197-1.2	E837G	Neutral	0.185
LRP5	O75197-1.2	E837H	Neutral	0.023
LRP5	O75197-1.2	E837I	Neutral	0.129
LRP5	O75197-1.2	E837K	Neutral	0.011
LRP5	O75197-1.2	E837L	Neutral	0.14
LRP5	O75197-1.2	E837M	Neutral	0.075
LRP5	O75197-1.2	E837N	Neutral	0.043
LRP5	O75197-1.2	E837P	Neutral	0.04
LRP5	O75197-1.2	E837Q	Neutral	0.004
LRP5	O75197-1.2	E837R	Neutral	0.031
LRP5	O75197-1.2	E837S	Neutral	0.026
LRP5	O75197-1.2	E837T	Neutral	0.06
LRP5	O75197-1.2	E837V	Neutral	0.077
LRP5	O75197-1.2	E837W	Neutral	0.085
LRP5	O75197-1.2	E837Y	Neutral	0.092
LRP5	O75197-1.2	R838A	Pathogenic	0.965
LRP5	O75197-1.2	R838C	Pathogenic	0.993
LRP5	O75197-1.2	R838D	Pathogenic	0.996
LRP5	O75197-1.2	R838E	Pathogenic	0.957
LRP5	O75197-1.2	R838F	Pathogenic	0.987
LRP5	O75197-1.2	R838G	Pathogenic	0.991
LRP5	O75197-1.2	R838H	Pathogenic	0.92
LRP5	O75197-1.2	R838I	Pathogenic	0.986
LRP5	O75197-1.2	R838K	Pathogenic	0.776
LRP5	O75197-1.2	R838L	Pathogenic	0.963
LRP5	O75197-1.2	R838M	Pathogenic	0.929
LRP5	O75197-1.2	R838N	Pathogenic	0.955
LRP5	O75197-1.2	R838P	Pathogenic	0.984
LRP5	O75197-1.2	R838Q	Pathogenic	0.836
LRP5	O75197-1.2	R838S	Pathogenic	0.974
LRP5	O75197-1.2	R838T	Pathogenic	0.968
LRP5	O75197-1.2	R838V	Pathogenic	0.992
LRP5	O75197-1.2	R838W	Pathogenic	0.98
LRP5	O75197-1.2	R838Y	Pathogenic	0.981
LRP5	O75197-1.2	V839A	Neutral	0.042
LRP5	O75197-1.2	V839C	Neutral	0.202
LRP5	O75197-1.2	V839D	Neutral	0.33
LRP5	O75197-1.2	V839E	Neutral	0.156
LRP5	O75197-1.2	V839F	Neutral	0.155
LRP5	O75197-1.2	V839G	Neutral	0.477
LRP5	O75197-1.2	V839H	Pathogenic	0.525
LRP5	O75197-1.2	V839I	Neutral	0.002
LRP5	O75197-1.2	V839K	Neutral	0.115
LRP5	O75197-1.2	V839L	Neutral	0.021
LRP5	O75197-1.2	V839M	Neutral	0.032
LRP5	O75197-1.2	V839N	Neutral	0.366
LRP5	O75197-1.2	V839P	Neutral	0.379
LRP5	O75197-1.2	V839Q	Neutral	0.21
LRP5	O75197-1.2	V839R	Neutral	0.276
LRP5	O75197-1.2	V839S	Neutral	0.232
LRP5	O75197-1.2	V839T	Neutral	0.042
LRP5	O75197-1.2	V839W	Pathogenic	0.518
LRP5	O75197-1.2	V839Y	Neutral	0.194
LRP5	O75197-1.2	V840A	Pathogenic	0.541
LRP5	O75197-1.2	V840C	Pathogenic	0.871
LRP5	O75197-1.2	V840D	Pathogenic	0.929
LRP5	O75197-1.2	V840E	Pathogenic	0.832
LRP5	O75197-1.2	V840F	Pathogenic	0.831
LRP5	O75197-1.2	V840G	Pathogenic	0.961
LRP5	O75197-1.2	V840H	Pathogenic	0.967
LRP5	O75197-1.2	V840I	Neutral	0.055
LRP5	O75197-1.2	V840K	Pathogenic	0.776
LRP5	O75197-1.2	V840L	Neutral	0.369
LRP5	O75197-1.2	V840M	Neutral	0.471
LRP5	O75197-1.2	V840N	Pathogenic	0.939
LRP5	O75197-1.2	V840P	Pathogenic	0.942
LRP5	O75197-1.2	V840Q	Pathogenic	0.877
LRP5	O75197-1.2	V840R	Pathogenic	0.911
LRP5	O75197-1.2	V840S	Pathogenic	0.89
LRP5	O75197-1.2	V840T	Pathogenic	0.54
LRP5	O75197-1.2	V840W	Pathogenic	0.966
LRP5	O75197-1.2	V840Y	Pathogenic	0.866
LRP5	O75197-1.2	I841A	Pathogenic	0.93
LRP5	O75197-1.2	I841C	Pathogenic	0.962
LRP5	O75197-1.2	I841D	Pathogenic	0.98
LRP5	O75197-1.2	I841E	Pathogenic	0.983
LRP5	O75197-1.2	I841F	Pathogenic	0.946
LRP5	O75197-1.2	I841G	Pathogenic	0.996
LRP5	O75197-1.2	I841H	Pathogenic	0.991
LRP5	O75197-1.2	I841K	Pathogenic	0.976
LRP5	O75197-1.2	I841L	Pathogenic	0.642
LRP5	O75197-1.2	I841M	Pathogenic	0.782
LRP5	O75197-1.2	I841N	Pathogenic	0.983
LRP5	O75197-1.2	I841P	Pathogenic	0.995
LRP5	O75197-1.2	I841Q	Pathogenic	0.988
LRP5	O75197-1.2	I841R	Pathogenic	0.976
LRP5	O75197-1.2	I841S	Pathogenic	0.968
LRP5	O75197-1.2	I841T	Pathogenic	0.93
LRP5	O75197-1.2	I841V	Neutral	0.271
LRP5	O75197-1.2	I841W	Pathogenic	0.997
LRP5	O75197-1.2	I841Y	Pathogenic	0.962
LRP5	O75197-1.2	A842C	Pathogenic	0.621
LRP5	O75197-1.2	A842D	Pathogenic	0.913
LRP5	O75197-1.2	A842E	Pathogenic	0.79
LRP5	O75197-1.2	A842F	Pathogenic	0.872
LRP5	O75197-1.2	A842G	Pathogenic	0.695
LRP5	O75197-1.2	A842H	Pathogenic	0.957
LRP5	O75197-1.2	A842I	Pathogenic	0.692
LRP5	O75197-1.2	A842K	Pathogenic	0.725
LRP5	O75197-1.2	A842L	Pathogenic	0.711
LRP5	O75197-1.2	A842M	Pathogenic	0.79
LRP5	O75197-1.2	A842N	Pathogenic	0.924
LRP5	O75197-1.2	A842P	Pathogenic	0.862
LRP5	O75197-1.2	A842Q	Pathogenic	0.845
LRP5	O75197-1.2	A842R	Pathogenic	0.718
LRP5	O75197-1.2	A842S	Neutral	0.425
LRP5	O75197-1.2	A842T	Pathogenic	0.739
LRP5	O75197-1.2	A842V	Pathogenic	0.563
LRP5	O75197-1.2	A842W	Pathogenic	0.929
LRP5	O75197-1.2	A842Y	Pathogenic	0.934
LRP5	O75197-1.2	D843A	Pathogenic	0.902
LRP5	O75197-1.2	D843C	Pathogenic	0.94
LRP5	O75197-1.2	D843E	Neutral	0.201
LRP5	O75197-1.2	D843F	Pathogenic	0.878
LRP5	O75197-1.2	D843G	Pathogenic	0.794
LRP5	O75197-1.2	D843H	Pathogenic	0.778
LRP5	O75197-1.2	D843I	Pathogenic	0.878
LRP5	O75197-1.2	D843K	Pathogenic	0.863
LRP5	O75197-1.2	D843L	Pathogenic	0.96
LRP5	O75197-1.2	D843M	Pathogenic	0.923
LRP5	O75197-1.2	D843N	Neutral	0.431
LRP5	O75197-1.2	D843P	Pathogenic	0.684
LRP5	O75197-1.2	D843Q	Pathogenic	0.614
LRP5	O75197-1.2	D843R	Pathogenic	0.949
LRP5	O75197-1.2	D843S	Pathogenic	0.577
LRP5	O75197-1.2	D843T	Pathogenic	0.766
LRP5	O75197-1.2	D843V	Pathogenic	0.926
LRP5	O75197-1.2	D843W	Pathogenic	0.933
LRP5	O75197-1.2	D843Y	Pathogenic	0.937
LRP5	O75197-1.2	D844A	Pathogenic	0.938
LRP5	O75197-1.2	D844C	Pathogenic	0.963
LRP5	O75197-1.2	D844E	Neutral	0.292
LRP5	O75197-1.2	D844F	Pathogenic	0.922
LRP5	O75197-1.2	D844G	Pathogenic	0.863
LRP5	O75197-1.2	D844H	Pathogenic	0.852
LRP5	O75197-1.2	D844I	Pathogenic	0.922
LRP5	O75197-1.2	D844K	Pathogenic	0.911
LRP5	O75197-1.2	D844L	Pathogenic	0.975
LRP5	O75197-1.2	D844M	Pathogenic	0.952
LRP5	O75197-1.2	D844N	Pathogenic	0.553
LRP5	O75197-1.2	D844P	Pathogenic	0.78
LRP5	O75197-1.2	D844Q	Pathogenic	0.723
LRP5	O75197-1.2	D844R	Pathogenic	0.968
LRP5	O75197-1.2	D844S	Pathogenic	0.69
LRP5	O75197-1.2	D844T	Pathogenic	0.843
LRP5	O75197-1.2	D844V	Pathogenic	0.954
LRP5	O75197-1.2	D844W	Pathogenic	0.958
LRP5	O75197-1.2	D844Y	Pathogenic	0.961
LRP5	O75197-1.2	L845A	Pathogenic	0.849
LRP5	O75197-1.2	L845C	Pathogenic	0.913
LRP5	O75197-1.2	L845D	Pathogenic	0.984
LRP5	O75197-1.2	L845E	Pathogenic	0.96
LRP5	O75197-1.2	L845F	Pathogenic	0.864
LRP5	O75197-1.2	L845G	Pathogenic	0.991
LRP5	O75197-1.2	L845H	Pathogenic	0.98
LRP5	O75197-1.2	L845I	Neutral	0.409
LRP5	O75197-1.2	L845K	Pathogenic	0.852
LRP5	O75197-1.2	L845M	Neutral	0.332
LRP5	O75197-1.2	L845N	Pathogenic	0.96
LRP5	O75197-1.2	L845P	Pathogenic	0.987
LRP5	O75197-1.2	L845Q	Pathogenic	0.92
LRP5	O75197-1.2	L845R	Pathogenic	0.848
LRP5	O75197-1.2	L845S	Pathogenic	0.927
LRP5	O75197-1.2	L845T	Pathogenic	0.848
LRP5	O75197-1.2	L845V	Pathogenic	0.592
LRP5	O75197-1.2	L845W	Pathogenic	0.974
LRP5	O75197-1.2	L845Y	Pathogenic	0.915
LRP5	O75197-1.2	P846A	Pathogenic	0.91
LRP5	O75197-1.2	P846C	Pathogenic	0.991
LRP5	O75197-1.2	P846D	Pathogenic	0.8
LRP5	O75197-1.2	P846E	Pathogenic	0.814
LRP5	O75197-1.2	P846F	Pathogenic	0.993
LRP5	O75197-1.2	P846G	Pathogenic	0.958
LRP5	O75197-1.2	P846H	Pathogenic	0.963
LRP5	O75197-1.2	P846I	Pathogenic	0.981
LRP5	O75197-1.2	P846K	Pathogenic	0.754
LRP5	O75197-1.2	P846L	Pathogenic	0.982
LRP5	O75197-1.2	P846M	Pathogenic	0.965
LRP5	O75197-1.2	P846N	Pathogenic	0.934
LRP5	O75197-1.2	P846Q	Pathogenic	0.863
LRP5	O75197-1.2	P846R	Pathogenic	0.9
LRP5	O75197-1.2	P846S	Pathogenic	0.883
LRP5	O75197-1.2	P846T	Pathogenic	0.909
LRP5	O75197-1.2	P846V	Pathogenic	0.967
LRP5	O75197-1.2	P846W	Pathogenic	0.99
LRP5	O75197-1.2	P846Y	Pathogenic	0.991
LRP5	O75197-1.2	H847A	Pathogenic	0.991
LRP5	O75197-1.2	H847C	Pathogenic	0.995
LRP5	O75197-1.2	H847D	Pathogenic	0.95
LRP5	O75197-1.2	H847E	Pathogenic	0.879
LRP5	O75197-1.2	H847F	Pathogenic	0.908
LRP5	O75197-1.2	H847G	Pathogenic	0.991
LRP5	O75197-1.2	H847I	Pathogenic	0.989
LRP5	O75197-1.2	H847K	Pathogenic	0.941
LRP5	O75197-1.2	H847L	Pathogenic	0.99
LRP5	O75197-1.2	H847M	Pathogenic	0.98
LRP5	O75197-1.2	H847N	Pathogenic	0.707
LRP5	O75197-1.2	H847P	Pathogenic	0.987
LRP5	O75197-1.2	H847Q	Pathogenic	0.914
LRP5	O75197-1.2	H847R	Pathogenic	0.835
LRP5	O75197-1.2	H847S	Pathogenic	0.973
LRP5	O75197-1.2	H847T	Pathogenic	0.991
LRP5	O75197-1.2	H847V	Pathogenic	0.993
LRP5	O75197-1.2	H847W	Pathogenic	0.95
LRP5	O75197-1.2	H847Y	Neutral	0.421
LRP5	O75197-1.2	P848A	Pathogenic	0.997
LRP5	O75197-1.2	P848C	Pathogenic	1.0
LRP5	O75197-1.2	P848D	Pathogenic	0.992
LRP5	O75197-1.2	P848E	Pathogenic	0.992
LRP5	O75197-1.2	P848F	Pathogenic	1.0
LRP5	O75197-1.2	P848G	Pathogenic	0.999
LRP5	O75197-1.2	P848H	Pathogenic	0.999
LRP5	O75197-1.2	P848I	Pathogenic	0.999
LRP5	O75197-1.2	P848K	Pathogenic	0.989
LRP5	O75197-1.2	P848L	Pathogenic	0.999
LRP5	O75197-1.2	P848M	Pathogenic	0.999
LRP5	O75197-1.2	P848N	Pathogenic	0.998
LRP5	O75197-1.2	P848Q	Pathogenic	0.995
LRP5	O75197-1.2	P848R	Pathogenic	0.996
LRP5	O75197-1.2	P848S	Pathogenic	0.996
LRP5	O75197-1.2	P848T	Pathogenic	0.997
LRP5	O75197-1.2	P848V	Pathogenic	0.999
LRP5	O75197-1.2	P848W	Pathogenic	1.0
LRP5	O75197-1.2	P848Y	Pathogenic	1.0
LRP5	O75197-1.2	F849A	Pathogenic	0.997
LRP5	O75197-1.2	F849C	Pathogenic	0.998
LRP5	O75197-1.2	F849D	Pathogenic	0.997
LRP5	O75197-1.2	F849E	Pathogenic	0.998
LRP5	O75197-1.2	F849G	Pathogenic	0.998
LRP5	O75197-1.2	F849H	Pathogenic	0.989
LRP5	O75197-1.2	F849I	Pathogenic	0.992
LRP5	O75197-1.2	F849K	Pathogenic	0.997
LRP5	O75197-1.2	F849L	Pathogenic	0.992
LRP5	O75197-1.2	F849M	Pathogenic	0.987
LRP5	O75197-1.2	F849N	Pathogenic	0.998
LRP5	O75197-1.2	F849P	Pathogenic	1.0
LRP5	O75197-1.2	F849Q	Pathogenic	0.998
LRP5	O75197-1.2	F849R	Pathogenic	0.997
LRP5	O75197-1.2	F849S	Pathogenic	0.995
LRP5	O75197-1.2	F849T	Pathogenic	0.997
LRP5	O75197-1.2	F849V	Pathogenic	0.996
LRP5	O75197-1.2	F849W	Pathogenic	0.965
LRP5	O75197-1.2	F849Y	Pathogenic	0.689
LRP5	O75197-1.2	G850A	Pathogenic	0.942
LRP5	O75197-1.2	G850C	Pathogenic	0.996
LRP5	O75197-1.2	G850D	Pathogenic	0.969
LRP5	O75197-1.2	G850E	Pathogenic	0.991
LRP5	O75197-1.2	G850F	Pathogenic	0.991
LRP5	O75197-1.2	G850H	Pathogenic	0.994
LRP5	O75197-1.2	G850I	Pathogenic	0.997
LRP5	O75197-1.2	G850K	Pathogenic	0.987
LRP5	O75197-1.2	G850L	Pathogenic	0.997
LRP5	O75197-1.2	G850M	Pathogenic	0.995
LRP5	O75197-1.2	G850N	Pathogenic	0.923
LRP5	O75197-1.2	G850P	Pathogenic	0.99
LRP5	O75197-1.2	G850Q	Pathogenic	0.993
LRP5	O75197-1.2	G850R	Pathogenic	0.986
LRP5	O75197-1.2	G850S	Pathogenic	0.954
LRP5	O75197-1.2	G850T	Pathogenic	0.993
LRP5	O75197-1.2	G850V	Pathogenic	0.995
LRP5	O75197-1.2	G850W	Pathogenic	0.958
LRP5	O75197-1.2	G850Y	Pathogenic	0.996
LRP5	O75197-1.2	L851A	Pathogenic	0.947
LRP5	O75197-1.2	L851C	Pathogenic	0.971
LRP5	O75197-1.2	L851D	Pathogenic	0.995
LRP5	O75197-1.2	L851E	Pathogenic	0.987
LRP5	O75197-1.2	L851F	Pathogenic	0.953
LRP5	O75197-1.2	L851G	Pathogenic	0.997
LRP5	O75197-1.2	L851H	Pathogenic	0.994
LRP5	O75197-1.2	L851I	Pathogenic	0.69
LRP5	O75197-1.2	L851K	Pathogenic	0.949
LRP5	O75197-1.2	L851M	Pathogenic	0.616
LRP5	O75197-1.2	L851N	Pathogenic	0.987
LRP5	O75197-1.2	L851P	Pathogenic	0.996
LRP5	O75197-1.2	L851Q	Pathogenic	0.974
LRP5	O75197-1.2	L851R	Pathogenic	0.947
LRP5	O75197-1.2	L851S	Pathogenic	0.976
LRP5	O75197-1.2	L851T	Pathogenic	0.947
LRP5	O75197-1.2	L851V	Pathogenic	0.823
LRP5	O75197-1.2	L851W	Pathogenic	0.992
LRP5	O75197-1.2	L851Y	Pathogenic	0.972
LRP5	O75197-1.2	T852A	Pathogenic	0.989
LRP5	O75197-1.2	T852C	Pathogenic	0.993
LRP5	O75197-1.2	T852D	Pathogenic	0.992
LRP5	O75197-1.2	T852E	Pathogenic	0.992
LRP5	O75197-1.2	T852F	Pathogenic	0.995
LRP5	O75197-1.2	T852G	Pathogenic	0.998
LRP5	O75197-1.2	T852H	Pathogenic	0.999
LRP5	O75197-1.2	T852I	Pathogenic	0.986
LRP5	O75197-1.2	T852K	Pathogenic	0.989
LRP5	O75197-1.2	T852L	Pathogenic	0.987
LRP5	O75197-1.2	T852M	Pathogenic	0.992
LRP5	O75197-1.2	T852N	Pathogenic	0.978
LRP5	O75197-1.2	T852P	Pathogenic	0.995
LRP5	O75197-1.2	T852Q	Pathogenic	0.995
LRP5	O75197-1.2	T852R	Pathogenic	0.989
LRP5	O75197-1.2	T852S	Pathogenic	0.96
LRP5	O75197-1.2	T852V	Pathogenic	0.976
LRP5	O75197-1.2	T852W	Pathogenic	0.993
LRP5	O75197-1.2	T852Y	Pathogenic	0.998
LRP5	O75197-1.2	Q853A	Pathogenic	0.998
LRP5	O75197-1.2	Q853C	Pathogenic	1.0
LRP5	O75197-1.2	Q853D	Pathogenic	0.993
LRP5	O75197-1.2	Q853E	Pathogenic	0.95
LRP5	O75197-1.2	Q853F	Pathogenic	0.999
LRP5	O75197-1.2	Q853G	Pathogenic	0.999
LRP5	O75197-1.2	Q853H	Pathogenic	0.995
LRP5	O75197-1.2	Q853I	Pathogenic	0.999
LRP5	O75197-1.2	Q853K	Pathogenic	0.976
LRP5	O75197-1.2	Q853L	Pathogenic	0.998
LRP5	O75197-1.2	Q853M	Pathogenic	0.986
LRP5	O75197-1.2	Q853N	Pathogenic	0.994
LRP5	O75197-1.2	Q853P	Pathogenic	0.997
LRP5	O75197-1.2	Q853R	Pathogenic	0.975
LRP5	O75197-1.2	Q853S	Pathogenic	0.995
LRP5	O75197-1.2	Q853T	Pathogenic	0.998
LRP5	O75197-1.2	Q853V	Pathogenic	0.998
LRP5	O75197-1.2	Q853W	Pathogenic	0.996
LRP5	O75197-1.2	Q853Y	Pathogenic	0.996
LRP5	O75197-1.2	Y854A	Pathogenic	0.999
LRP5	O75197-1.2	Y854C	Pathogenic	1.0
LRP5	O75197-1.2	Y854D	Pathogenic	0.999
LRP5	O75197-1.2	Y854E	Pathogenic	0.998
LRP5	O75197-1.2	Y854F	Pathogenic	0.824
LRP5	O75197-1.2	Y854G	Pathogenic	1.0
LRP5	O75197-1.2	Y854H	Pathogenic	0.933
LRP5	O75197-1.2	Y854I	Pathogenic	0.997
LRP5	O75197-1.2	Y854K	Pathogenic	0.998
LRP5	O75197-1.2	Y854L	Pathogenic	0.998
LRP5	O75197-1.2	Y854M	Pathogenic	0.998
LRP5	O75197-1.2	Y854N	Pathogenic	0.998
LRP5	O75197-1.2	Y854P	Pathogenic	1.0
LRP5	O75197-1.2	Y854Q	Pathogenic	0.996
LRP5	O75197-1.2	Y854R	Pathogenic	0.998
LRP5	O75197-1.2	Y854S	Pathogenic	0.999
LRP5	O75197-1.2	Y854T	Pathogenic	0.999
LRP5	O75197-1.2	Y854V	Pathogenic	0.998
LRP5	O75197-1.2	Y854W	Pathogenic	0.902
LRP5	O75197-1.2	S855A	Neutral	0.026
LRP5	O75197-1.2	S855C	Neutral	0.117
LRP5	O75197-1.2	S855D	Neutral	0.053
LRP5	O75197-1.2	S855E	Neutral	0.058
LRP5	O75197-1.2	S855F	Neutral	0.154
LRP5	O75197-1.2	S855G	Neutral	0.094
LRP5	O75197-1.2	S855H	Neutral	0.213
LRP5	O75197-1.2	S855I	Neutral	0.154
LRP5	O75197-1.2	S855K	Neutral	0.041
LRP5	O75197-1.2	S855L	Neutral	0.167
LRP5	O75197-1.2	S855M	Neutral	0.091
LRP5	O75197-1.2	S855N	Neutral	0.021
LRP5	O75197-1.2	S855P	Neutral	0.143
LRP5	O75197-1.2	S855Q	Neutral	0.081
LRP5	O75197-1.2	S855R	Neutral	0.112
LRP5	O75197-1.2	S855T	Neutral	0.026
LRP5	O75197-1.2	S855V	Neutral	0.241
LRP5	O75197-1.2	S855W	Neutral	0.259
LRP5	O75197-1.2	S855Y	Neutral	0.274
LRP5	O75197-1.2	D856A	Pathogenic	0.995
LRP5	O75197-1.2	D856C	Pathogenic	0.997
LRP5	O75197-1.2	D856E	Pathogenic	0.848
LRP5	O75197-1.2	D856F	Pathogenic	0.994
LRP5	O75197-1.2	D856G	Pathogenic	0.988
LRP5	O75197-1.2	D856H	Pathogenic	0.987
LRP5	O75197-1.2	D856I	Pathogenic	0.994
LRP5	O75197-1.2	D856K	Pathogenic	0.993
LRP5	O75197-1.2	D856L	Pathogenic	0.998
LRP5	O75197-1.2	D856M	Pathogenic	0.996
LRP5	O75197-1.2	D856N	Pathogenic	0.944
LRP5	O75197-1.2	D856P	Pathogenic	0.98
LRP5	O75197-1.2	D856Q	Pathogenic	0.973
LRP5	O75197-1.2	D856R	Pathogenic	0.998
LRP5	O75197-1.2	D856S	Pathogenic	0.968
LRP5	O75197-1.2	D856T	Pathogenic	0.986
LRP5	O75197-1.2	D856V	Pathogenic	0.996
LRP5	O75197-1.2	D856W	Pathogenic	0.997
LRP5	O75197-1.2	D856Y	Pathogenic	0.997
LRP5	O75197-1.2	Y857A	Pathogenic	0.995
LRP5	O75197-1.2	Y857C	Pathogenic	0.997
LRP5	O75197-1.2	Y857D	Pathogenic	0.996
LRP5	O75197-1.2	Y857E	Pathogenic	0.989
LRP5	O75197-1.2	Y857F	Neutral	0.429
LRP5	O75197-1.2	Y857G	Pathogenic	0.998
LRP5	O75197-1.2	Y857H	Pathogenic	0.69
LRP5	O75197-1.2	Y857I	Pathogenic	0.984
LRP5	O75197-1.2	Y857K	Pathogenic	0.986
LRP5	O75197-1.2	Y857L	Pathogenic	0.986
LRP5	O75197-1.2	Y857M	Pathogenic	0.99
LRP5	O75197-1.2	Y857N	Pathogenic	0.99
LRP5	O75197-1.2	Y857P	Pathogenic	0.999
LRP5	O75197-1.2	Y857Q	Pathogenic	0.978
LRP5	O75197-1.2	Y857R	Pathogenic	0.986
LRP5	O75197-1.2	Y857S	Pathogenic	0.993
LRP5	O75197-1.2	Y857T	Pathogenic	0.995
LRP5	O75197-1.2	Y857V	Pathogenic	0.99
LRP5	O75197-1.2	Y857W	Pathogenic	0.595
LRP5	O75197-1.2	I858A	Pathogenic	0.978
LRP5	O75197-1.2	I858C	Pathogenic	0.988
LRP5	O75197-1.2	I858D	Pathogenic	0.994
LRP5	O75197-1.2	I858E	Pathogenic	0.995
LRP5	O75197-1.2	I858F	Pathogenic	0.984
LRP5	O75197-1.2	I858G	Pathogenic	0.999
LRP5	O75197-1.2	I858H	Pathogenic	0.997
LRP5	O75197-1.2	I858K	Pathogenic	0.993
LRP5	O75197-1.2	I858L	Pathogenic	0.86
LRP5	O75197-1.2	I858M	Pathogenic	0.925
LRP5	O75197-1.2	I858N	Pathogenic	0.995
LRP5	O75197-1.2	I858P	Pathogenic	0.998
LRP5	O75197-1.2	I858Q	Pathogenic	0.996
LRP5	O75197-1.2	I858R	Pathogenic	0.993
LRP5	O75197-1.2	I858S	Pathogenic	0.99
LRP5	O75197-1.2	I858T	Pathogenic	0.978
LRP5	O75197-1.2	I858V	Pathogenic	0.56
LRP5	O75197-1.2	I858W	Pathogenic	0.999
LRP5	O75197-1.2	I858Y	Pathogenic	0.989
LRP5	O75197-1.2	Y859A	Pathogenic	0.999
LRP5	O75197-1.2	Y859C	Pathogenic	1.0
LRP5	O75197-1.2	Y859D	Pathogenic	0.999
LRP5	O75197-1.2	Y859E	Pathogenic	0.998
LRP5	O75197-1.2	Y859F	Pathogenic	0.824
LRP5	O75197-1.2	Y859G	Pathogenic	1.0
LRP5	O75197-1.2	Y859H	Pathogenic	0.933
LRP5	O75197-1.2	Y859I	Pathogenic	0.997
LRP5	O75197-1.2	Y859K	Pathogenic	0.998
LRP5	O75197-1.2	Y859L	Pathogenic	0.998
LRP5	O75197-1.2	Y859M	Pathogenic	0.998
LRP5	O75197-1.2	Y859N	Pathogenic	0.998
LRP5	O75197-1.2	Y859P	Pathogenic	1.0
LRP5	O75197-1.2	Y859Q	Pathogenic	0.996
LRP5	O75197-1.2	Y859R	Pathogenic	0.998
LRP5	O75197-1.2	Y859S	Pathogenic	0.999
LRP5	O75197-1.2	Y859T	Pathogenic	0.999
LRP5	O75197-1.2	Y859V	Pathogenic	0.998
LRP5	O75197-1.2	Y859W	Pathogenic	0.902
LRP5	O75197-1.2	W860A	Pathogenic	1.0
LRP5	O75197-1.2	W860C	Pathogenic	0.999
LRP5	O75197-1.2	W860D	Pathogenic	1.0
LRP5	O75197-1.2	W860E	Pathogenic	0.999
LRP5	O75197-1.2	W860F	Pathogenic	0.991
LRP5	O75197-1.2	W860G	Pathogenic	0.998
LRP5	O75197-1.2	W860H	Pathogenic	0.999
LRP5	O75197-1.2	W860I	Pathogenic	1.0
LRP5	O75197-1.2	W860K	Pathogenic	0.999
LRP5	O75197-1.2	W860L	Pathogenic	1.0
LRP5	O75197-1.2	W860M	Pathogenic	0.998
LRP5	O75197-1.2	W860N	Pathogenic	1.0
LRP5	O75197-1.2	W860P	Pathogenic	1.0
LRP5	O75197-1.2	W860Q	Pathogenic	0.998
LRP5	O75197-1.2	W860R	Pathogenic	0.999
LRP5	O75197-1.2	W860S	Pathogenic	0.999
LRP5	O75197-1.2	W860T	Pathogenic	0.999
LRP5	O75197-1.2	W860V	Pathogenic	1.0
LRP5	O75197-1.2	W860Y	Pathogenic	0.945
LRP5	O75197-1.2	T861A	Pathogenic	0.98
LRP5	O75197-1.2	T861C	Pathogenic	0.988
LRP5	O75197-1.2	T861D	Pathogenic	0.984
LRP5	O75197-1.2	T861E	Pathogenic	0.986
LRP5	O75197-1.2	T861F	Pathogenic	0.991
LRP5	O75197-1.2	T861G	Pathogenic	0.997
LRP5	O75197-1.2	T861H	Pathogenic	0.998
LRP5	O75197-1.2	T861I	Pathogenic	0.974
LRP5	O75197-1.2	T861K	Pathogenic	0.98
LRP5	O75197-1.2	T861L	Pathogenic	0.977
LRP5	O75197-1.2	T861M	Pathogenic	0.984
LRP5	O75197-1.2	T861N	Pathogenic	0.96
LRP5	O75197-1.2	T861P	Pathogenic	0.991
LRP5	O75197-1.2	T861Q	Pathogenic	0.99
LRP5	O75197-1.2	T861R	Pathogenic	0.979
LRP5	O75197-1.2	T861S	Pathogenic	0.928
LRP5	O75197-1.2	T861V	Pathogenic	0.956
LRP5	O75197-1.2	T861W	Pathogenic	0.986
LRP5	O75197-1.2	T861Y	Pathogenic	0.996
LRP5	O75197-1.2	D862A	Pathogenic	0.997
LRP5	O75197-1.2	D862C	Pathogenic	0.998
LRP5	O75197-1.2	D862E	Pathogenic	0.907
LRP5	O75197-1.2	D862F	Pathogenic	0.996
LRP5	O75197-1.2	D862G	Pathogenic	0.993
LRP5	O75197-1.2	D862H	Pathogenic	0.993
LRP5	O75197-1.2	D862I	Pathogenic	0.996
LRP5	O75197-1.2	D862K	Pathogenic	0.996
LRP5	O75197-1.2	D862L	Pathogenic	0.999
LRP5	O75197-1.2	D862M	Pathogenic	0.998
LRP5	O75197-1.2	D862N	Pathogenic	0.967
LRP5	O75197-1.2	D862P	Pathogenic	0.988
LRP5	O75197-1.2	D862Q	Pathogenic	0.984
LRP5	O75197-1.2	D862R	Pathogenic	0.999
LRP5	O75197-1.2	D862S	Pathogenic	0.981
LRP5	O75197-1.2	D862T	Pathogenic	0.992
LRP5	O75197-1.2	D862V	Pathogenic	0.998
LRP5	O75197-1.2	D862W	Pathogenic	0.998
LRP5	O75197-1.2	D862Y	Pathogenic	0.998
LRP5	O75197-1.2	W863A	Pathogenic	0.998
LRP5	O75197-1.2	W863C	Pathogenic	0.997
LRP5	O75197-1.2	W863D	Pathogenic	0.999
LRP5	O75197-1.2	W863E	Pathogenic	0.997
LRP5	O75197-1.2	W863F	Pathogenic	0.968
LRP5	O75197-1.2	W863G	Pathogenic	0.993
LRP5	O75197-1.2	W863H	Pathogenic	0.995
LRP5	O75197-1.2	W863I	Pathogenic	1.0
LRP5	O75197-1.2	W863K	Pathogenic	0.995
LRP5	O75197-1.2	W863L	Pathogenic	0.999
LRP5	O75197-1.2	W863M	Pathogenic	0.994
LRP5	O75197-1.2	W863N	Pathogenic	0.999
LRP5	O75197-1.2	W863P	Pathogenic	1.0
LRP5	O75197-1.2	W863Q	Pathogenic	0.993
LRP5	O75197-1.2	W863R	Pathogenic	0.995
LRP5	O75197-1.2	W863S	Pathogenic	0.998
LRP5	O75197-1.2	W863T	Pathogenic	0.995
LRP5	O75197-1.2	W863V	Pathogenic	0.999
LRP5	O75197-1.2	W863Y	Pathogenic	0.828
LRP5	O75197-1.2	N864A	Pathogenic	0.81
LRP5	O75197-1.2	N864C	Pathogenic	0.879
LRP5	O75197-1.2	N864D	Neutral	0.233
LRP5	O75197-1.2	N864E	Pathogenic	0.507
LRP5	O75197-1.2	N864F	Pathogenic	0.772
LRP5	O75197-1.2	N864G	Neutral	0.37
LRP5	O75197-1.2	N864H	Neutral	0.152
LRP5	O75197-1.2	N864I	Pathogenic	0.773
LRP5	O75197-1.2	N864K	Neutral	0.419
LRP5	O75197-1.2	N864L	Pathogenic	0.788
LRP5	O75197-1.2	N864M	Pathogenic	0.651
LRP5	O75197-1.2	N864P	Pathogenic	0.753
LRP5	O75197-1.2	N864Q	Neutral	0.428
LRP5	O75197-1.2	N864R	Neutral	0.41
LRP5	O75197-1.2	N864S	Neutral	0.172
LRP5	O75197-1.2	N864T	Neutral	0.334
LRP5	O75197-1.2	N864V	Pathogenic	0.856
LRP5	O75197-1.2	N864W	Pathogenic	0.867
LRP5	O75197-1.2	N864Y	Pathogenic	0.698
LRP5	O75197-1.2	L865A	Neutral	0.107
LRP5	O75197-1.2	L865C	Neutral	0.184
LRP5	O75197-1.2	L865D	Pathogenic	0.572
LRP5	O75197-1.2	L865E	Neutral	0.337
LRP5	O75197-1.2	L865F	Neutral	0.12
LRP5	O75197-1.2	L865G	Pathogenic	0.713
LRP5	O75197-1.2	L865H	Pathogenic	0.507
LRP5	O75197-1.2	L865I	Neutral	0.015
LRP5	O75197-1.2	L865K	Neutral	0.109
LRP5	O75197-1.2	L865M	Neutral	0.011
LRP5	O75197-1.2	L865N	Neutral	0.34
LRP5	O75197-1.2	L865P	Pathogenic	0.624
LRP5	O75197-1.2	L865Q	Neutral	0.197
LRP5	O75197-1.2	L865R	Neutral	0.106
LRP5	O75197-1.2	L865S	Neutral	0.213
LRP5	O75197-1.2	L865T	Neutral	0.106
LRP5	O75197-1.2	L865V	Neutral	0.03
LRP5	O75197-1.2	L865W	Neutral	0.443
LRP5	O75197-1.2	L865Y	Neutral	0.186
LRP5	O75197-1.2	H866A	Pathogenic	0.867
LRP5	O75197-1.2	H866C	Pathogenic	0.918
LRP5	O75197-1.2	H866D	Pathogenic	0.537
LRP5	O75197-1.2	H866E	Neutral	0.306
LRP5	O75197-1.2	H866F	Neutral	0.375
LRP5	O75197-1.2	H866G	Pathogenic	0.868
LRP5	O75197-1.2	H866I	Pathogenic	0.848
LRP5	O75197-1.2	H866K	Neutral	0.492
LRP5	O75197-1.2	H866L	Pathogenic	0.859
LRP5	O75197-1.2	H866M	Pathogenic	0.753
LRP5	O75197-1.2	H866N	Neutral	0.128
LRP5	O75197-1.2	H866P	Pathogenic	0.824
LRP5	O75197-1.2	H866Q	Neutral	0.393
LRP5	O75197-1.2	H866R	Neutral	0.235
LRP5	O75197-1.2	H866S	Pathogenic	0.685
LRP5	O75197-1.2	H866T	Pathogenic	0.876
LRP5	O75197-1.2	H866V	Pathogenic	0.903
LRP5	O75197-1.2	H866W	Pathogenic	0.536
LRP5	O75197-1.2	H866Y	Neutral	0.042
LRP5	O75197-1.2	S867A	Pathogenic	0.77
LRP5	O75197-1.2	S867C	Pathogenic	0.944
LRP5	O75197-1.2	S867D	Pathogenic	0.876
LRP5	O75197-1.2	S867E	Pathogenic	0.885
LRP5	O75197-1.2	S867F	Pathogenic	0.958
LRP5	O75197-1.2	S867G	Pathogenic	0.929
LRP5	O75197-1.2	S867H	Pathogenic	0.972
LRP5	O75197-1.2	S867I	Pathogenic	0.958
LRP5	O75197-1.2	S867K	Pathogenic	0.844
LRP5	O75197-1.2	S867L	Pathogenic	0.962
LRP5	O75197-1.2	S867M	Pathogenic	0.927
LRP5	O75197-1.2	S867N	Pathogenic	0.728
LRP5	O75197-1.2	S867P	Pathogenic	0.955
LRP5	O75197-1.2	S867Q	Pathogenic	0.918
LRP5	O75197-1.2	S867R	Pathogenic	0.941
LRP5	O75197-1.2	S867T	Pathogenic	0.774
LRP5	O75197-1.2	S867V	Pathogenic	0.976
LRP5	O75197-1.2	S867W	Pathogenic	0.978
LRP5	O75197-1.2	S867Y	Pathogenic	0.979
LRP5	O75197-1.2	I868A	Pathogenic	0.991
LRP5	O75197-1.2	I868C	Pathogenic	0.995
LRP5	O75197-1.2	I868D	Pathogenic	0.997
LRP5	O75197-1.2	I868E	Pathogenic	0.998
LRP5	O75197-1.2	I868F	Pathogenic	0.993
LRP5	O75197-1.2	I868G	Pathogenic	1.0
LRP5	O75197-1.2	I868H	Pathogenic	0.999
LRP5	O75197-1.2	I868K	Pathogenic	0.997
LRP5	O75197-1.2	I868L	Pathogenic	0.935
LRP5	O75197-1.2	I868M	Pathogenic	0.966
LRP5	O75197-1.2	I868N	Pathogenic	0.998
LRP5	O75197-1.2	I868P	Pathogenic	0.999
LRP5	O75197-1.2	I868Q	Pathogenic	0.998
LRP5	O75197-1.2	I868R	Pathogenic	0.997
LRP5	O75197-1.2	I868S	Pathogenic	0.996
LRP5	O75197-1.2	I868T	Pathogenic	0.991
LRP5	O75197-1.2	I868V	Pathogenic	0.747
LRP5	O75197-1.2	I868W	Pathogenic	1.0
LRP5	O75197-1.2	I868Y	Pathogenic	0.995
LRP5	O75197-1.2	E869A	Pathogenic	0.995
LRP5	O75197-1.2	E869C	Pathogenic	1.0
LRP5	O75197-1.2	E869D	Pathogenic	0.935
LRP5	O75197-1.2	E869F	Pathogenic	0.998
LRP5	O75197-1.2	E869G	Pathogenic	0.999
LRP5	O75197-1.2	E869H	Pathogenic	0.987
LRP5	O75197-1.2	E869I	Pathogenic	0.998
LRP5	O75197-1.2	E869K	Pathogenic	0.972
LRP5	O75197-1.2	E869L	Pathogenic	0.998
LRP5	O75197-1.2	E869M	Pathogenic	0.996
LRP5	O75197-1.2	E869N	Pathogenic	0.993
LRP5	O75197-1.2	E869P	Pathogenic	0.993
LRP5	O75197-1.2	E869Q	Pathogenic	0.919
LRP5	O75197-1.2	E869R	Pathogenic	0.99
LRP5	O75197-1.2	E869S	Pathogenic	0.988
LRP5	O75197-1.2	E869T	Pathogenic	0.995
LRP5	O75197-1.2	E869V	Pathogenic	0.996
LRP5	O75197-1.2	E869W	Pathogenic	0.997
LRP5	O75197-1.2	E869Y	Pathogenic	0.997
LRP5	O75197-1.2	R870A	Pathogenic	0.982
LRP5	O75197-1.2	R870C	Pathogenic	0.997
LRP5	O75197-1.2	R870D	Pathogenic	0.998
LRP5	O75197-1.2	R870E	Pathogenic	0.978
LRP5	O75197-1.2	R870F	Pathogenic	0.993
LRP5	O75197-1.2	R870G	Pathogenic	0.995
LRP5	O75197-1.2	R870H	Pathogenic	0.958
LRP5	O75197-1.2	R870I	Pathogenic	0.993
LRP5	O75197-1.2	R870K	Pathogenic	0.875
LRP5	O75197-1.2	R870L	Pathogenic	0.981
LRP5	O75197-1.2	R870M	Pathogenic	0.964
LRP5	O75197-1.2	R870N	Pathogenic	0.977
LRP5	O75197-1.2	R870P	Pathogenic	0.992
LRP5	O75197-1.2	R870Q	Pathogenic	0.912
LRP5	O75197-1.2	R870S	Pathogenic	0.987
LRP5	O75197-1.2	R870T	Pathogenic	0.984
LRP5	O75197-1.2	R870V	Pathogenic	0.996
LRP5	O75197-1.2	R870W	Pathogenic	0.99
LRP5	O75197-1.2	R870Y	Pathogenic	0.991
LRP5	O75197-1.2	A871C	Pathogenic	0.985
LRP5	O75197-1.2	A871D	Pathogenic	0.998
LRP5	O75197-1.2	A871E	Pathogenic	0.993
LRP5	O75197-1.2	A871F	Pathogenic	0.996
LRP5	O75197-1.2	A871G	Pathogenic	0.989
LRP5	O75197-1.2	A871H	Pathogenic	0.999
LRP5	O75197-1.2	A871I	Pathogenic	0.989
LRP5	O75197-1.2	A871K	Pathogenic	0.99
LRP5	O75197-1.2	A871L	Pathogenic	0.99
LRP5	O75197-1.2	A871M	Pathogenic	0.993
LRP5	O75197-1.2	A871N	Pathogenic	0.998
LRP5	O75197-1.2	A871P	Pathogenic	0.996
LRP5	O75197-1.2	A871Q	Pathogenic	0.995
LRP5	O75197-1.2	A871R	Pathogenic	0.99
LRP5	O75197-1.2	A871S	Pathogenic	0.966
LRP5	O75197-1.2	A871T	Pathogenic	0.991
LRP5	O75197-1.2	A871V	Pathogenic	0.98
LRP5	O75197-1.2	A871W	Pathogenic	0.998
LRP5	O75197-1.2	A871Y	Pathogenic	0.998
LRP5	O75197-1.2	D872A	Pathogenic	0.832
LRP5	O75197-1.2	D872C	Pathogenic	0.894
LRP5	O75197-1.2	D872E	Neutral	0.119
LRP5	O75197-1.2	D872F	Pathogenic	0.795
LRP5	O75197-1.2	D872G	Pathogenic	0.675
LRP5	O75197-1.2	D872H	Pathogenic	0.654
LRP5	O75197-1.2	D872I	Pathogenic	0.795
LRP5	O75197-1.2	D872K	Pathogenic	0.772
LRP5	O75197-1.2	D872L	Pathogenic	0.928
LRP5	O75197-1.2	D872M	Pathogenic	0.866
LRP5	O75197-1.2	D872N	Neutral	0.29
LRP5	O75197-1.2	D872P	Pathogenic	0.538
LRP5	O75197-1.2	D872Q	Neutral	0.461
LRP5	O75197-1.2	D872R	Pathogenic	0.909
LRP5	O75197-1.2	D872S	Neutral	0.423
LRP5	O75197-1.2	D872T	Pathogenic	0.638
LRP5	O75197-1.2	D872V	Pathogenic	0.871
LRP5	O75197-1.2	D872W	Pathogenic	0.882
LRP5	O75197-1.2	D872Y	Pathogenic	0.889
LRP5	O75197-1.2	K873A	Pathogenic	0.996
LRP5	O75197-1.2	K873C	Pathogenic	0.999
LRP5	O75197-1.2	K873D	Pathogenic	0.999
LRP5	O75197-1.2	K873E	Pathogenic	0.985
LRP5	O75197-1.2	K873F	Pathogenic	0.999
LRP5	O75197-1.2	K873G	Pathogenic	0.999
LRP5	O75197-1.2	K873H	Pathogenic	0.997
LRP5	O75197-1.2	K873I	Pathogenic	0.998
LRP5	O75197-1.2	K873L	Pathogenic	0.996
LRP5	O75197-1.2	K873M	Pathogenic	0.992
LRP5	O75197-1.2	K873N	Pathogenic	0.995
LRP5	O75197-1.2	K873P	Pathogenic	0.994
LRP5	O75197-1.2	K873Q	Pathogenic	0.979
LRP5	O75197-1.2	K873R	Pathogenic	0.968
LRP5	O75197-1.2	K873S	Pathogenic	0.991
LRP5	O75197-1.2	K873T	Pathogenic	0.996
LRP5	O75197-1.2	K873V	Pathogenic	0.997
LRP5	O75197-1.2	K873W	Pathogenic	0.998
LRP5	O75197-1.2	K873Y	Pathogenic	0.998
LRP5	O75197-1.2	T874A	Pathogenic	0.768
LRP5	O75197-1.2	T874C	Pathogenic	0.851
LRP5	O75197-1.2	T874D	Pathogenic	0.814
LRP5	O75197-1.2	T874E	Pathogenic	0.828
LRP5	O75197-1.2	T874F	Pathogenic	0.888
LRP5	O75197-1.2	T874G	Pathogenic	0.961
LRP5	O75197-1.2	T874H	Pathogenic	0.966
LRP5	O75197-1.2	T874I	Pathogenic	0.724
LRP5	O75197-1.2	T874K	Pathogenic	0.772
LRP5	O75197-1.2	T874L	Pathogenic	0.742
LRP5	O75197-1.2	T874M	Pathogenic	0.814
LRP5	O75197-1.2	T874N	Pathogenic	0.626
LRP5	O75197-1.2	T874P	Pathogenic	0.879
LRP5	O75197-1.2	T874Q	Pathogenic	0.874
LRP5	O75197-1.2	T874R	Pathogenic	0.765
LRP5	O75197-1.2	T874S	Neutral	0.47
LRP5	O75197-1.2	T874V	Pathogenic	0.601
LRP5	O75197-1.2	T874W	Pathogenic	0.834
LRP5	O75197-1.2	T874Y	Pathogenic	0.943
LRP5	O75197-1.2	S875A	Neutral	0.426
LRP5	O75197-1.2	S875C	Pathogenic	0.788
LRP5	O75197-1.2	S875D	Pathogenic	0.61
LRP5	O75197-1.2	S875E	Pathogenic	0.631
LRP5	O75197-1.2	S875F	Pathogenic	0.835
LRP5	O75197-1.2	S875G	Pathogenic	0.742
LRP5	O75197-1.2	S875H	Pathogenic	0.883
LRP5	O75197-1.2	S875I	Pathogenic	0.836
LRP5	O75197-1.2	S875K	Pathogenic	0.545
LRP5	O75197-1.2	S875L	Pathogenic	0.848
LRP5	O75197-1.2	S875M	Pathogenic	0.736
LRP5	O75197-1.2	S875N	Neutral	0.372
LRP5	O75197-1.2	S875P	Pathogenic	0.824
LRP5	O75197-1.2	S875Q	Pathogenic	0.711
LRP5	O75197-1.2	S875R	Pathogenic	0.779
LRP5	O75197-1.2	S875T	Neutral	0.431
LRP5	O75197-1.2	S875V	Pathogenic	0.899
LRP5	O75197-1.2	S875W	Pathogenic	0.907
LRP5	O75197-1.2	S875Y	Pathogenic	0.913
LRP5	O75197-1.2	G876A	Pathogenic	0.989
LRP5	O75197-1.2	G876C	Pathogenic	0.999
LRP5	O75197-1.2	G876D	Pathogenic	0.994
LRP5	O75197-1.2	G876E	Pathogenic	0.998
LRP5	O75197-1.2	G876F	Pathogenic	0.998
LRP5	O75197-1.2	G876H	Pathogenic	0.999
LRP5	O75197-1.2	G876I	Pathogenic	0.999
LRP5	O75197-1.2	G876K	Pathogenic	0.998
LRP5	O75197-1.2	G876L	Pathogenic	1.0
LRP5	O75197-1.2	G876M	Pathogenic	0.999
LRP5	O75197-1.2	G876N	Pathogenic	0.985
LRP5	O75197-1.2	G876P	Pathogenic	0.998
LRP5	O75197-1.2	G876Q	Pathogenic	0.999
LRP5	O75197-1.2	G876R	Pathogenic	0.997
LRP5	O75197-1.2	G876S	Pathogenic	0.991
LRP5	O75197-1.2	G876T	Pathogenic	0.999
LRP5	O75197-1.2	G876V	Pathogenic	0.999
LRP5	O75197-1.2	G876W	Pathogenic	0.992
LRP5	O75197-1.2	G876Y	Pathogenic	0.999
LRP5	O75197-1.2	R877A	Neutral	0.009
LRP5	O75197-1.2	R877C	Neutral	0.047
LRP5	O75197-1.2	R877D	Neutral	0.073
LRP5	O75197-1.2	R877E	Neutral	0.008
LRP5	O75197-1.2	R877F	Neutral	0.025
LRP5	O75197-1.2	R877G	Neutral	0.035
LRP5	O75197-1.2	R877H	Neutral	0.004
LRP5	O75197-1.2	R877I	Neutral	0.025
LRP5	O75197-1.2	R877K	Neutral	0.001
LRP5	O75197-1.2	R877L	Neutral	0.009
LRP5	O75197-1.2	R877M	Neutral	0.005
LRP5	O75197-1.2	R877N	Neutral	0.007
LRP5	O75197-1.2	R877P	Neutral	0.02
LRP5	O75197-1.2	R877Q	Neutral	0.002
LRP5	O75197-1.2	R877S	Neutral	0.013
LRP5	O75197-1.2	R877T	Neutral	0.01
LRP5	O75197-1.2	R877V	Neutral	0.04
LRP5	O75197-1.2	R877W	Neutral	0.017
LRP5	O75197-1.2	R877Y	Neutral	0.018
LRP5	O75197-1.2	N878A	Pathogenic	0.999
LRP5	O75197-1.2	N878C	Pathogenic	0.999
LRP5	O75197-1.2	N878D	Pathogenic	0.98
LRP5	O75197-1.2	N878E	Pathogenic	0.994
LRP5	O75197-1.2	N878F	Pathogenic	0.998
LRP5	O75197-1.2	N878G	Pathogenic	0.99
LRP5	O75197-1.2	N878H	Pathogenic	0.967
LRP5	O75197-1.2	N878I	Pathogenic	0.998
LRP5	O75197-1.2	N878K	Pathogenic	0.992
LRP5	O75197-1.2	N878L	Pathogenic	0.998
LRP5	O75197-1.2	N878M	Pathogenic	0.997
LRP5	O75197-1.2	N878P	Pathogenic	0.998
LRP5	O75197-1.2	N878Q	Pathogenic	0.992
LRP5	O75197-1.2	N878R	Pathogenic	0.991
LRP5	O75197-1.2	N878S	Pathogenic	0.972
LRP5	O75197-1.2	N878T	Pathogenic	0.988
LRP5	O75197-1.2	N878V	Pathogenic	0.999
LRP5	O75197-1.2	N878W	Pathogenic	0.999
LRP5	O75197-1.2	N878Y	Pathogenic	0.997
LRP5	O75197-1.2	R879A	Pathogenic	0.989
LRP5	O75197-1.2	R879C	Pathogenic	0.998
LRP5	O75197-1.2	R879D	Pathogenic	0.999
LRP5	O75197-1.2	R879E	Pathogenic	0.987
LRP5	O75197-1.2	R879F	Pathogenic	0.996
LRP5	O75197-1.2	R879G	Pathogenic	0.997
LRP5	O75197-1.2	R879H	Pathogenic	0.975
LRP5	O75197-1.2	R879I	Pathogenic	0.996
LRP5	O75197-1.2	R879K	Pathogenic	0.921
LRP5	O75197-1.2	R879L	Pathogenic	0.989
LRP5	O75197-1.2	R879M	Pathogenic	0.978
LRP5	O75197-1.2	R879N	Pathogenic	0.986
LRP5	O75197-1.2	R879P	Pathogenic	0.995
LRP5	O75197-1.2	R879Q	Pathogenic	0.945
LRP5	O75197-1.2	R879S	Pathogenic	0.992
LRP5	O75197-1.2	R879T	Pathogenic	0.99
LRP5	O75197-1.2	R879V	Pathogenic	0.998
LRP5	O75197-1.2	R879W	Pathogenic	0.994
LRP5	O75197-1.2	R879Y	Pathogenic	0.994
LRP5	O75197-1.2	T880A	Pathogenic	0.986
LRP5	O75197-1.2	T880C	Pathogenic	0.992
LRP5	O75197-1.2	T880D	Pathogenic	0.989
LRP5	O75197-1.2	T880E	Pathogenic	0.99
LRP5	O75197-1.2	T880F	Pathogenic	0.994
LRP5	O75197-1.2	T880G	Pathogenic	0.998
LRP5	O75197-1.2	T880H	Pathogenic	0.998
LRP5	O75197-1.2	T880I	Pathogenic	0.982
LRP5	O75197-1.2	T880K	Pathogenic	0.986
LRP5	O75197-1.2	T880L	Pathogenic	0.984
LRP5	O75197-1.2	T880M	Pathogenic	0.989
LRP5	O75197-1.2	T880N	Pathogenic	0.972
LRP5	O75197-1.2	T880P	Pathogenic	0.994
LRP5	O75197-1.2	T880Q	Pathogenic	0.993
LRP5	O75197-1.2	T880R	Pathogenic	0.986
LRP5	O75197-1.2	T880S	Pathogenic	0.949
LRP5	O75197-1.2	T880V	Pathogenic	0.969
LRP5	O75197-1.2	T880W	Pathogenic	0.991
LRP5	O75197-1.2	T880Y	Pathogenic	0.997
LRP5	O75197-1.2	L881A	Neutral	0.027
LRP5	O75197-1.2	L881C	Neutral	0.05
LRP5	O75197-1.2	L881D	Neutral	0.236
LRP5	O75197-1.2	L881E	Neutral	0.105
LRP5	O75197-1.2	L881F	Neutral	0.031
LRP5	O75197-1.2	L881G	Neutral	0.365
LRP5	O75197-1.2	L881H	Neutral	0.192
LRP5	O75197-1.2	L881I	Neutral	0.003
LRP5	O75197-1.2	L881K	Neutral	0.028
LRP5	O75197-1.2	L881M	Neutral	0.002
LRP5	O75197-1.2	L881N	Neutral	0.106
LRP5	O75197-1.2	L881P	Neutral	0.277
LRP5	O75197-1.2	L881Q	Neutral	0.054
LRP5	O75197-1.2	L881R	Neutral	0.027
LRP5	O75197-1.2	L881S	Neutral	0.059
LRP5	O75197-1.2	L881T	Neutral	0.027
LRP5	O75197-1.2	L881V	Neutral	0.007
LRP5	O75197-1.2	L881W	Neutral	0.156
LRP5	O75197-1.2	L881Y	Neutral	0.05
LRP5	O75197-1.2	I882A	Pathogenic	0.939
LRP5	O75197-1.2	I882C	Pathogenic	0.966
LRP5	O75197-1.2	I882D	Pathogenic	0.982
LRP5	O75197-1.2	I882E	Pathogenic	0.985
LRP5	O75197-1.2	I882F	Pathogenic	0.953
LRP5	O75197-1.2	I882G	Pathogenic	0.997
LRP5	O75197-1.2	I882H	Pathogenic	0.992
LRP5	O75197-1.2	I882K	Pathogenic	0.979
LRP5	O75197-1.2	I882L	Pathogenic	0.674
LRP5	O75197-1.2	I882M	Pathogenic	0.805
LRP5	O75197-1.2	I882N	Pathogenic	0.985
LRP5	O75197-1.2	I882P	Pathogenic	0.995
LRP5	O75197-1.2	I882Q	Pathogenic	0.99
LRP5	O75197-1.2	I882R	Pathogenic	0.979
LRP5	O75197-1.2	I882S	Pathogenic	0.972
LRP5	O75197-1.2	I882T	Pathogenic	0.938
LRP5	O75197-1.2	I882V	Neutral	0.299
LRP5	O75197-1.2	I882W	Pathogenic	0.997
LRP5	O75197-1.2	I882Y	Pathogenic	0.967
LRP5	O75197-1.2	Q883A	Pathogenic	0.986
LRP5	O75197-1.2	Q883C	Pathogenic	0.997
LRP5	O75197-1.2	Q883D	Pathogenic	0.959
LRP5	O75197-1.2	Q883E	Pathogenic	0.744
LRP5	O75197-1.2	Q883F	Pathogenic	0.994
LRP5	O75197-1.2	Q883G	Pathogenic	0.996
LRP5	O75197-1.2	Q883H	Pathogenic	0.966
LRP5	O75197-1.2	Q883I	Pathogenic	0.994
LRP5	O75197-1.2	Q883K	Pathogenic	0.863
LRP5	O75197-1.2	Q883L	Pathogenic	0.985
LRP5	O75197-1.2	Q883M	Pathogenic	0.914
LRP5	O75197-1.2	Q883N	Pathogenic	0.965
LRP5	O75197-1.2	Q883P	Pathogenic	0.98
LRP5	O75197-1.2	Q883R	Pathogenic	0.859
LRP5	O75197-1.2	Q883S	Pathogenic	0.969
LRP5	O75197-1.2	Q883T	Pathogenic	0.987
LRP5	O75197-1.2	Q883V	Pathogenic	0.99
LRP5	O75197-1.2	Q883W	Pathogenic	0.974
LRP5	O75197-1.2	Q883Y	Pathogenic	0.976
LRP5	O75197-1.2	G884A	Pathogenic	0.805
LRP5	O75197-1.2	G884C	Pathogenic	0.984
LRP5	O75197-1.2	G884D	Pathogenic	0.889
LRP5	O75197-1.2	G884E	Pathogenic	0.964
LRP5	O75197-1.2	G884F	Pathogenic	0.965
LRP5	O75197-1.2	G884H	Pathogenic	0.976
LRP5	O75197-1.2	G884I	Pathogenic	0.988
LRP5	O75197-1.2	G884K	Pathogenic	0.949
LRP5	O75197-1.2	G884L	Pathogenic	0.989
LRP5	O75197-1.2	G884M	Pathogenic	0.979
LRP5	O75197-1.2	G884N	Pathogenic	0.752
LRP5	O75197-1.2	G884P	Pathogenic	0.962
LRP5	O75197-1.2	G884Q	Pathogenic	0.975
LRP5	O75197-1.2	G884R	Pathogenic	0.947
LRP5	O75197-1.2	G884S	Pathogenic	0.839
LRP5	O75197-1.2	G884T	Pathogenic	0.975
LRP5	O75197-1.2	G884V	Pathogenic	0.98
LRP5	O75197-1.2	G884W	Pathogenic	0.852
LRP5	O75197-1.2	G884Y	Pathogenic	0.983
LRP5	O75197-1.2	H885A	Pathogenic	0.978
LRP5	O75197-1.2	H885C	Pathogenic	0.987
LRP5	O75197-1.2	H885D	Pathogenic	0.888
LRP5	O75197-1.2	H885E	Pathogenic	0.75
LRP5	O75197-1.2	H885F	Pathogenic	0.803
LRP5	O75197-1.2	H885G	Pathogenic	0.978
LRP5	O75197-1.2	H885I	Pathogenic	0.974
LRP5	O75197-1.2	H885K	Pathogenic	0.868
LRP5	O75197-1.2	H885L	Pathogenic	0.977
LRP5	O75197-1.2	H885M	Pathogenic	0.954
LRP5	O75197-1.2	H885N	Pathogenic	0.5
LRP5	O75197-1.2	H885P	Pathogenic	0.97
LRP5	O75197-1.2	H885Q	Pathogenic	0.815
LRP5	O75197-1.2	H885R	Pathogenic	0.677
LRP5	O75197-1.2	H885S	Pathogenic	0.937
LRP5	O75197-1.2	H885T	Pathogenic	0.98
LRP5	O75197-1.2	H885V	Pathogenic	0.984
LRP5	O75197-1.2	H885W	Pathogenic	0.887
LRP5	O75197-1.2	H885Y	Neutral	0.232
LRP5	O75197-1.2	L886A	Pathogenic	0.958
LRP5	O75197-1.2	L886C	Pathogenic	0.977
LRP5	O75197-1.2	L886D	Pathogenic	0.996
LRP5	O75197-1.2	L886E	Pathogenic	0.99
LRP5	O75197-1.2	L886F	Pathogenic	0.962
LRP5	O75197-1.2	L886G	Pathogenic	0.998
LRP5	O75197-1.2	L886H	Pathogenic	0.995
LRP5	O75197-1.2	L886I	Pathogenic	0.736
LRP5	O75197-1.2	L886K	Pathogenic	0.959
LRP5	O75197-1.2	L886M	Pathogenic	0.667
LRP5	O75197-1.2	L886N	Pathogenic	0.99
LRP5	O75197-1.2	L886P	Pathogenic	0.997
LRP5	O75197-1.2	L886Q	Pathogenic	0.979
LRP5	O75197-1.2	L886R	Pathogenic	0.957
LRP5	O75197-1.2	L886S	Pathogenic	0.981
LRP5	O75197-1.2	L886T	Pathogenic	0.957
LRP5	O75197-1.2	L886V	Pathogenic	0.854
LRP5	O75197-1.2	L886W	Pathogenic	0.993
LRP5	O75197-1.2	L886Y	Pathogenic	0.977
LRP5	O75197-1.2	D887A	Pathogenic	0.939
LRP5	O75197-1.2	D887C	Pathogenic	0.963
LRP5	O75197-1.2	D887E	Neutral	0.295
LRP5	O75197-1.2	D887F	Pathogenic	0.923
LRP5	O75197-1.2	D887G	Pathogenic	0.865
LRP5	O75197-1.2	D887H	Pathogenic	0.854
LRP5	O75197-1.2	D887I	Pathogenic	0.923
LRP5	O75197-1.2	D887K	Pathogenic	0.913
LRP5	O75197-1.2	D887L	Pathogenic	0.976
LRP5	O75197-1.2	D887M	Pathogenic	0.952
LRP5	O75197-1.2	D887N	Pathogenic	0.558
LRP5	O75197-1.2	D887P	Pathogenic	0.783
LRP5	O75197-1.2	D887Q	Pathogenic	0.726
LRP5	O75197-1.2	D887R	Pathogenic	0.969
LRP5	O75197-1.2	D887S	Pathogenic	0.694
LRP5	O75197-1.2	D887T	Pathogenic	0.845
LRP5	O75197-1.2	D887V	Pathogenic	0.954
LRP5	O75197-1.2	D887W	Pathogenic	0.958
LRP5	O75197-1.2	D887Y	Pathogenic	0.961
LRP5	O75197-1.2	F888A	Pathogenic	0.596
LRP5	O75197-1.2	F888C	Pathogenic	0.735
LRP5	O75197-1.2	F888D	Pathogenic	0.64
LRP5	O75197-1.2	F888E	Pathogenic	0.673
LRP5	O75197-1.2	F888G	Pathogenic	0.768
LRP5	O75197-1.2	F888H	Neutral	0.31
LRP5	O75197-1.2	F888I	Neutral	0.393
LRP5	O75197-1.2	F888K	Pathogenic	0.611
LRP5	O75197-1.2	F888L	Neutral	0.378
LRP5	O75197-1.2	F888M	Neutral	0.285
LRP5	O75197-1.2	F888N	Pathogenic	0.676
LRP5	O75197-1.2	F888P	Pathogenic	0.953
LRP5	O75197-1.2	F888Q	Pathogenic	0.751
LRP5	O75197-1.2	F888R	Pathogenic	0.602
LRP5	O75197-1.2	F888S	Pathogenic	0.522
LRP5	O75197-1.2	F888T	Pathogenic	0.595
LRP5	O75197-1.2	F888V	Pathogenic	0.537
LRP5	O75197-1.2	F888W	Neutral	0.122
LRP5	O75197-1.2	F888Y	Neutral	0.011
LRP5	O75197-1.2	V889A	Pathogenic	0.947
LRP5	O75197-1.2	V889C	Pathogenic	0.99
LRP5	O75197-1.2	V889D	Pathogenic	0.995
LRP5	O75197-1.2	V889E	Pathogenic	0.987
LRP5	O75197-1.2	V889F	Pathogenic	0.987
LRP5	O75197-1.2	V889G	Pathogenic	0.997
LRP5	O75197-1.2	V889H	Pathogenic	0.998
LRP5	O75197-1.2	V889I	Neutral	0.465
LRP5	O75197-1.2	V889K	Pathogenic	0.981
LRP5	O75197-1.2	V889L	Pathogenic	0.898
LRP5	O75197-1.2	V889M	Pathogenic	0.931
LRP5	O75197-1.2	V889N	Pathogenic	0.996
LRP5	O75197-1.2	V889P	Pathogenic	0.996
LRP5	O75197-1.2	V889Q	Pathogenic	0.991
LRP5	O75197-1.2	V889R	Pathogenic	0.994
LRP5	O75197-1.2	V889S	Pathogenic	0.992
LRP5	O75197-1.2	V889T	Pathogenic	0.946
LRP5	O75197-1.2	V889W	Pathogenic	0.998
LRP5	O75197-1.2	V889Y	Pathogenic	0.99
LRP5	O75197-1.2	M890A	Pathogenic	0.986
LRP5	O75197-1.2	M890C	Pathogenic	0.992
LRP5	O75197-1.2	M890D	Pathogenic	0.996
LRP5	O75197-1.2	M890E	Pathogenic	0.99
LRP5	O75197-1.2	M890F	Pathogenic	0.971
LRP5	O75197-1.2	M890G	Pathogenic	0.998
LRP5	O75197-1.2	M890H	Pathogenic	0.995
LRP5	O75197-1.2	M890I	Pathogenic	0.918
LRP5	O75197-1.2	M890K	Pathogenic	0.959
LRP5	O75197-1.2	M890L	Pathogenic	0.801
LRP5	O75197-1.2	M890N	Pathogenic	0.99
LRP5	O75197-1.2	M890P	Pathogenic	0.997
LRP5	O75197-1.2	M890Q	Pathogenic	0.938
LRP5	O75197-1.2	M890R	Pathogenic	0.957
LRP5	O75197-1.2	M890S	Pathogenic	0.981
LRP5	O75197-1.2	M890T	Pathogenic	0.986
LRP5	O75197-1.2	M890V	Pathogenic	0.947
LRP5	O75197-1.2	M890W	Pathogenic	0.985
LRP5	O75197-1.2	M890Y	Pathogenic	0.992
LRP5	O75197-1.2	D891A	Pathogenic	0.996
LRP5	O75197-1.2	D891C	Pathogenic	0.998
LRP5	O75197-1.2	D891E	Pathogenic	0.871
LRP5	O75197-1.2	D891F	Pathogenic	0.995
LRP5	O75197-1.2	D891G	Pathogenic	0.99
LRP5	O75197-1.2	D891H	Pathogenic	0.99
LRP5	O75197-1.2	D891I	Pathogenic	0.995
LRP5	O75197-1.2	D891K	Pathogenic	0.994
LRP5	O75197-1.2	D891L	Pathogenic	0.998
LRP5	O75197-1.2	D891M	Pathogenic	0.997
LRP5	O75197-1.2	D891N	Pathogenic	0.953
LRP5	O75197-1.2	D891P	Pathogenic	0.983
LRP5	O75197-1.2	D891Q	Pathogenic	0.977
LRP5	O75197-1.2	D891R	Pathogenic	0.998
LRP5	O75197-1.2	D891S	Pathogenic	0.973
LRP5	O75197-1.2	D891T	Pathogenic	0.989
LRP5	O75197-1.2	D891V	Pathogenic	0.997
LRP5	O75197-1.2	D891W	Pathogenic	0.997
LRP5	O75197-1.2	D891Y	Pathogenic	0.998
LRP5	O75197-1.2	I892A	Pathogenic	0.967
LRP5	O75197-1.2	I892C	Pathogenic	0.982
LRP5	O75197-1.2	I892D	Pathogenic	0.991
LRP5	O75197-1.2	I892E	Pathogenic	0.992
LRP5	O75197-1.2	I892F	Pathogenic	0.975
LRP5	O75197-1.2	I892G	Pathogenic	0.998
LRP5	O75197-1.2	I892H	Pathogenic	0.996
LRP5	O75197-1.2	I892K	Pathogenic	0.989
LRP5	O75197-1.2	I892L	Pathogenic	0.796
LRP5	O75197-1.2	I892M	Pathogenic	0.887
LRP5	O75197-1.2	I892N	Pathogenic	0.992
LRP5	O75197-1.2	I892P	Pathogenic	0.998
LRP5	O75197-1.2	I892Q	Pathogenic	0.994
LRP5	O75197-1.2	I892R	Pathogenic	0.989
LRP5	O75197-1.2	I892S	Pathogenic	0.985
LRP5	O75197-1.2	I892T	Pathogenic	0.966
LRP5	O75197-1.2	I892V	Neutral	0.447
LRP5	O75197-1.2	I892W	Pathogenic	0.999
LRP5	O75197-1.2	I892Y	Pathogenic	0.982
LRP5	O75197-1.2	L893A	Pathogenic	0.937
LRP5	O75197-1.2	L893C	Pathogenic	0.966
LRP5	O75197-1.2	L893D	Pathogenic	0.994
LRP5	O75197-1.2	L893E	Pathogenic	0.984
LRP5	O75197-1.2	L893F	Pathogenic	0.944
LRP5	O75197-1.2	L893G	Pathogenic	0.997
LRP5	O75197-1.2	L893H	Pathogenic	0.992
LRP5	O75197-1.2	L893I	Pathogenic	0.648
LRP5	O75197-1.2	L893K	Pathogenic	0.939
LRP5	O75197-1.2	L893M	Pathogenic	0.57
LRP5	O75197-1.2	L893N	Pathogenic	0.985
LRP5	O75197-1.2	L893P	Pathogenic	0.995
LRP5	O75197-1.2	L893Q	Pathogenic	0.968
LRP5	O75197-1.2	L893R	Pathogenic	0.937
LRP5	O75197-1.2	L893S	Pathogenic	0.971
LRP5	O75197-1.2	L893T	Pathogenic	0.937
LRP5	O75197-1.2	L893V	Pathogenic	0.794
LRP5	O75197-1.2	L893W	Pathogenic	0.99
LRP5	O75197-1.2	L893Y	Pathogenic	0.966
LRP5	O75197-1.2	V894A	Pathogenic	0.978
LRP5	O75197-1.2	V894C	Pathogenic	0.996
LRP5	O75197-1.2	V894D	Pathogenic	0.998
LRP5	O75197-1.2	V894E	Pathogenic	0.995
LRP5	O75197-1.2	V894F	Pathogenic	0.995
LRP5	O75197-1.2	V894G	Pathogenic	0.999
LRP5	O75197-1.2	V894H	Pathogenic	0.999
LRP5	O75197-1.2	V894I	Pathogenic	0.683
LRP5	O75197-1.2	V894K	Pathogenic	0.992
LRP5	O75197-1.2	V894L	Pathogenic	0.956
LRP5	O75197-1.2	V894M	Pathogenic	0.971
LRP5	O75197-1.2	V894N	Pathogenic	0.998
LRP5	O75197-1.2	V894P	Pathogenic	0.998
LRP5	O75197-1.2	V894Q	Pathogenic	0.996
LRP5	O75197-1.2	V894R	Pathogenic	0.997
LRP5	O75197-1.2	V894S	Pathogenic	0.997
LRP5	O75197-1.2	V894T	Pathogenic	0.978
LRP5	O75197-1.2	V894W	Pathogenic	0.999
LRP5	O75197-1.2	V894Y	Pathogenic	0.996
LRP5	O75197-1.2	F895A	Pathogenic	0.999
LRP5	O75197-1.2	F895C	Pathogenic	0.999
LRP5	O75197-1.2	F895D	Pathogenic	0.999
LRP5	O75197-1.2	F895E	Pathogenic	0.999
LRP5	O75197-1.2	F895G	Pathogenic	0.999
LRP5	O75197-1.2	F895H	Pathogenic	0.995
LRP5	O75197-1.2	F895I	Pathogenic	0.997
LRP5	O75197-1.2	F895K	Pathogenic	0.999
LRP5	O75197-1.2	F895L	Pathogenic	0.997
LRP5	O75197-1.2	F895M	Pathogenic	0.995
LRP5	O75197-1.2	F895N	Pathogenic	0.999
LRP5	O75197-1.2	F895P	Pathogenic	1.0
LRP5	O75197-1.2	F895Q	Pathogenic	0.999
LRP5	O75197-1.2	F895R	Pathogenic	0.999
LRP5	O75197-1.2	F895S	Pathogenic	0.998
LRP5	O75197-1.2	F895T	Pathogenic	0.999
LRP5	O75197-1.2	F895V	Pathogenic	0.998
LRP5	O75197-1.2	F895W	Pathogenic	0.985
LRP5	O75197-1.2	F895Y	Pathogenic	0.841
LRP5	O75197-1.2	H896A	Pathogenic	1.0
LRP5	O75197-1.2	H896C	Pathogenic	1.0
LRP5	O75197-1.2	H896D	Pathogenic	0.998
LRP5	O75197-1.2	H896E	Pathogenic	0.996
LRP5	O75197-1.2	H896F	Pathogenic	0.997
LRP5	O75197-1.2	H896G	Pathogenic	1.0
LRP5	O75197-1.2	H896I	Pathogenic	1.0
LRP5	O75197-1.2	H896K	Pathogenic	0.998
LRP5	O75197-1.2	H896L	Pathogenic	1.0
LRP5	O75197-1.2	H896M	Pathogenic	0.999
LRP5	O75197-1.2	H896N	Pathogenic	0.987
LRP5	O75197-1.2	H896P	Pathogenic	1.0
LRP5	O75197-1.2	H896Q	Pathogenic	0.997
LRP5	O75197-1.2	H896R	Pathogenic	0.994
LRP5	O75197-1.2	H896S	Pathogenic	0.999
LRP5	O75197-1.2	H896T	Pathogenic	1.0
LRP5	O75197-1.2	H896V	Pathogenic	1.0
LRP5	O75197-1.2	H896W	Pathogenic	0.998
LRP5	O75197-1.2	H896Y	Pathogenic	0.957
LRP5	O75197-1.2	S897A	Pathogenic	0.686
LRP5	O75197-1.2	S897C	Pathogenic	0.916
LRP5	O75197-1.2	S897D	Pathogenic	0.822
LRP5	O75197-1.2	S897E	Pathogenic	0.834
LRP5	O75197-1.2	S897F	Pathogenic	0.937
LRP5	O75197-1.2	S897G	Pathogenic	0.895
LRP5	O75197-1.2	S897H	Pathogenic	0.957
LRP5	O75197-1.2	S897I	Pathogenic	0.938
LRP5	O75197-1.2	S897K	Pathogenic	0.779
LRP5	O75197-1.2	S897L	Pathogenic	0.943
LRP5	O75197-1.2	S897M	Pathogenic	0.892
LRP5	O75197-1.2	S897N	Pathogenic	0.636
LRP5	O75197-1.2	S897P	Pathogenic	0.932
LRP5	O75197-1.2	S897Q	Pathogenic	0.879
LRP5	O75197-1.2	S897R	Pathogenic	0.912
LRP5	O75197-1.2	S897T	Pathogenic	0.691
LRP5	O75197-1.2	S897V	Pathogenic	0.963
LRP5	O75197-1.2	S897W	Pathogenic	0.966
LRP5	O75197-1.2	S897Y	Pathogenic	0.969
LRP5	O75197-1.2	S898A	Pathogenic	0.956
LRP5	O75197-1.2	S898C	Pathogenic	0.991
LRP5	O75197-1.2	S898D	Pathogenic	0.979
LRP5	O75197-1.2	S898E	Pathogenic	0.98
LRP5	O75197-1.2	S898F	Pathogenic	0.993
LRP5	O75197-1.2	S898G	Pathogenic	0.988
LRP5	O75197-1.2	S898H	Pathogenic	0.995
LRP5	O75197-1.2	S898I	Pathogenic	0.993
LRP5	O75197-1.2	S898K	Pathogenic	0.972
LRP5	O75197-1.2	S898L	Pathogenic	0.994
LRP5	O75197-1.2	S898M	Pathogenic	0.988
LRP5	O75197-1.2	S898N	Pathogenic	0.945
LRP5	O75197-1.2	S898P	Pathogenic	0.993
LRP5	O75197-1.2	S898Q	Pathogenic	0.986
LRP5	O75197-1.2	S898R	Pathogenic	0.99
LRP5	O75197-1.2	S898T	Pathogenic	0.957
LRP5	O75197-1.2	S898V	Pathogenic	0.996
LRP5	O75197-1.2	S898W	Pathogenic	0.997
LRP5	O75197-1.2	S898Y	Pathogenic	0.997
LRP5	O75197-1.2	R899A	Pathogenic	0.99
LRP5	O75197-1.2	R899C	Pathogenic	0.998
LRP5	O75197-1.2	R899D	Pathogenic	0.999
LRP5	O75197-1.2	R899E	Pathogenic	0.988
LRP5	O75197-1.2	R899F	Pathogenic	0.996
LRP5	O75197-1.2	R899G	Pathogenic	0.998
LRP5	O75197-1.2	R899H	Pathogenic	0.977
LRP5	O75197-1.2	R899I	Pathogenic	0.996
LRP5	O75197-1.2	R899K	Pathogenic	0.929
LRP5	O75197-1.2	R899L	Pathogenic	0.99
LRP5	O75197-1.2	R899M	Pathogenic	0.98
LRP5	O75197-1.2	R899N	Pathogenic	0.988
LRP5	O75197-1.2	R899P	Pathogenic	0.996
LRP5	O75197-1.2	R899Q	Pathogenic	0.951
LRP5	O75197-1.2	R899S	Pathogenic	0.993
LRP5	O75197-1.2	R899T	Pathogenic	0.991
LRP5	O75197-1.2	R899V	Pathogenic	0.998
LRP5	O75197-1.2	R899W	Pathogenic	0.995
LRP5	O75197-1.2	R899Y	Pathogenic	0.995
LRP5	O75197-1.2	Q900A	Pathogenic	0.998
LRP5	O75197-1.2	Q900C	Pathogenic	1.0
LRP5	O75197-1.2	Q900D	Pathogenic	0.993
LRP5	O75197-1.2	Q900E	Pathogenic	0.95
LRP5	O75197-1.2	Q900F	Pathogenic	0.999
LRP5	O75197-1.2	Q900G	Pathogenic	0.999
LRP5	O75197-1.2	Q900H	Pathogenic	0.995
LRP5	O75197-1.2	Q900I	Pathogenic	0.999
LRP5	O75197-1.2	Q900K	Pathogenic	0.976
LRP5	O75197-1.2	Q900L	Pathogenic	0.998
LRP5	O75197-1.2	Q900M	Pathogenic	0.986
LRP5	O75197-1.2	Q900N	Pathogenic	0.994
LRP5	O75197-1.2	Q900P	Pathogenic	0.997
LRP5	O75197-1.2	Q900R	Pathogenic	0.975
LRP5	O75197-1.2	Q900S	Pathogenic	0.995
LRP5	O75197-1.2	Q900T	Pathogenic	0.998
LRP5	O75197-1.2	Q900V	Pathogenic	0.998
LRP5	O75197-1.2	Q900W	Pathogenic	0.996
LRP5	O75197-1.2	Q900Y	Pathogenic	0.996
LRP5	O75197-1.2	D901A	Neutral	0.24
LRP5	O75197-1.2	D901C	Neutral	0.351
LRP5	O75197-1.2	D901E	Neutral	0.009
LRP5	O75197-1.2	D901F	Neutral	0.198
LRP5	O75197-1.2	D901G	Neutral	0.117
LRP5	O75197-1.2	D901H	Neutral	0.108
LRP5	O75197-1.2	D901I	Neutral	0.199
LRP5	O75197-1.2	D901K	Neutral	0.178
LRP5	O75197-1.2	D901L	Neutral	0.453
LRP5	O75197-1.2	D901M	Neutral	0.293
LRP5	O75197-1.2	D901N	Neutral	0.025
LRP5	O75197-1.2	D901P	Neutral	0.069
LRP5	O75197-1.2	D901Q	Neutral	0.052
LRP5	O75197-1.2	D901R	Neutral	0.389
LRP5	O75197-1.2	D901S	Neutral	0.045
LRP5	O75197-1.2	D901T	Neutral	0.101
LRP5	O75197-1.2	D901V	Neutral	0.302
LRP5	O75197-1.2	D901W	Neutral	0.322
LRP5	O75197-1.2	D901Y	Neutral	0.339
LRP5	O75197-1.2	G902A	Pathogenic	0.983
LRP5	O75197-1.2	G902C	Pathogenic	0.999
LRP5	O75197-1.2	G902D	Pathogenic	0.991
LRP5	O75197-1.2	G902E	Pathogenic	0.997
LRP5	O75197-1.2	G902F	Pathogenic	0.997
LRP5	O75197-1.2	G902H	Pathogenic	0.998
LRP5	O75197-1.2	G902I	Pathogenic	0.999
LRP5	O75197-1.2	G902K	Pathogenic	0.996
LRP5	O75197-1.2	G902L	Pathogenic	0.999
LRP5	O75197-1.2	G902M	Pathogenic	0.998
LRP5	O75197-1.2	G902N	Pathogenic	0.977
LRP5	O75197-1.2	G902P	Pathogenic	0.997
LRP5	O75197-1.2	G902Q	Pathogenic	0.998
LRP5	O75197-1.2	G902R	Pathogenic	0.996
LRP5	O75197-1.2	G902S	Pathogenic	0.986
LRP5	O75197-1.2	G902T	Pathogenic	0.998
LRP5	O75197-1.2	G902V	Pathogenic	0.999
LRP5	O75197-1.2	G902W	Pathogenic	0.988
LRP5	O75197-1.2	G902Y	Pathogenic	0.999
LRP5	O75197-1.2	L903A	Neutral	0.054
LRP5	O75197-1.2	L903C	Neutral	0.098
LRP5	O75197-1.2	L903D	Neutral	0.391
LRP5	O75197-1.2	L903E	Neutral	0.196
LRP5	O75197-1.2	L903F	Neutral	0.061
LRP5	O75197-1.2	L903G	Pathogenic	0.544
LRP5	O75197-1.2	L903H	Neutral	0.331
LRP5	O75197-1.2	L903I	Neutral	0.007
LRP5	O75197-1.2	L903K	Neutral	0.056
LRP5	O75197-1.2	L903M	Neutral	0.005
LRP5	O75197-1.2	L903N	Neutral	0.198
LRP5	O75197-1.2	L903P	Neutral	0.444
LRP5	O75197-1.2	L903Q	Neutral	0.105
LRP5	O75197-1.2	L903R	Neutral	0.054
LRP5	O75197-1.2	L903S	Neutral	0.115
LRP5	O75197-1.2	L903T	Neutral	0.054
LRP5	O75197-1.2	L903V	Neutral	0.015
LRP5	O75197-1.2	L903W	Neutral	0.277
LRP5	O75197-1.2	L903Y	Neutral	0.099
LRP5	O75197-1.2	N904A	Pathogenic	0.59
LRP5	O75197-1.2	N904C	Pathogenic	0.712
LRP5	O75197-1.2	N904D	Neutral	0.093
LRP5	O75197-1.2	N904E	Neutral	0.258
LRP5	O75197-1.2	N904F	Pathogenic	0.534
LRP5	O75197-1.2	N904G	Neutral	0.166
LRP5	O75197-1.2	N904H	Neutral	0.057
LRP5	O75197-1.2	N904I	Pathogenic	0.535
LRP5	O75197-1.2	N904K	Neutral	0.196
LRP5	O75197-1.2	N904L	Pathogenic	0.558
LRP5	O75197-1.2	N904M	Neutral	0.387
LRP5	O75197-1.2	N904P	Pathogenic	0.509
LRP5	O75197-1.2	N904Q	Neutral	0.203
LRP5	O75197-1.2	N904R	Neutral	0.191
LRP5	O75197-1.2	N904S	Neutral	0.066
LRP5	O75197-1.2	N904T	Neutral	0.145
LRP5	O75197-1.2	N904V	Pathogenic	0.667
LRP5	O75197-1.2	N904W	Pathogenic	0.688
LRP5	O75197-1.2	N904Y	Neutral	0.439
LRP5	O75197-1.2	D905A	Neutral	0.0
LRP5	O75197-1.2	D905C	Neutral	0.0
LRP5	O75197-1.2	D905E	Neutral	0.0
LRP5	O75197-1.2	D905F	Neutral	0.0
LRP5	O75197-1.2	D905G	Neutral	0.0
LRP5	O75197-1.2	D905H	Neutral	0.0
LRP5	O75197-1.2	D905I	Neutral	0.0
LRP5	O75197-1.2	D905K	Neutral	0.0
LRP5	O75197-1.2	D905L	Neutral	0.001
LRP5	O75197-1.2	D905M	Neutral	0.0
LRP5	O75197-1.2	D905N	Neutral	0.0
LRP5	O75197-1.2	D905P	Neutral	0.0
LRP5	O75197-1.2	D905Q	Neutral	0.0
LRP5	O75197-1.2	D905R	Neutral	0.001
LRP5	O75197-1.2	D905S	Neutral	0.0
LRP5	O75197-1.2	D905T	Neutral	0.0
LRP5	O75197-1.2	D905V	Neutral	0.0
LRP5	O75197-1.2	D905W	Neutral	0.0
LRP5	O75197-1.2	D905Y	Neutral	0.0
LRP5	O75197-1.2	C906A	Pathogenic	0.993
LRP5	O75197-1.2	C906D	Pathogenic	0.999
LRP5	O75197-1.2	C906E	Pathogenic	1.0
LRP5	O75197-1.2	C906F	Pathogenic	0.999
LRP5	O75197-1.2	C906G	Pathogenic	1.0
LRP5	O75197-1.2	C906H	Pathogenic	1.0
LRP5	O75197-1.2	C906I	Pathogenic	0.997
LRP5	O75197-1.2	C906K	Pathogenic	0.999
LRP5	O75197-1.2	C906L	Pathogenic	0.997
LRP5	O75197-1.2	C906M	Pathogenic	0.998
LRP5	O75197-1.2	C906N	Pathogenic	0.999
LRP5	O75197-1.2	C906P	Pathogenic	1.0
LRP5	O75197-1.2	C906Q	Pathogenic	1.0
LRP5	O75197-1.2	C906R	Pathogenic	0.999
LRP5	O75197-1.2	C906S	Pathogenic	0.997
LRP5	O75197-1.2	C906T	Pathogenic	0.998
LRP5	O75197-1.2	C906V	Pathogenic	0.998
LRP5	O75197-1.2	C906W	Pathogenic	0.999
LRP5	O75197-1.2	C906Y	Pathogenic	1.0
LRP5	O75197-1.2	M907A	Neutral	0.0
LRP5	O75197-1.2	M907C	Neutral	0.0
LRP5	O75197-1.2	M907D	Neutral	0.001
LRP5	O75197-1.2	M907E	Neutral	0.0
LRP5	O75197-1.2	M907F	Neutral	0.0
LRP5	O75197-1.2	M907G	Neutral	0.001
LRP5	O75197-1.2	M907H	Neutral	0.0
LRP5	O75197-1.2	M907I	Neutral	0.0
LRP5	O75197-1.2	M907K	Neutral	0.0
LRP5	O75197-1.2	M907L	Neutral	0.0
LRP5	O75197-1.2	M907N	Neutral	0.0
LRP5	O75197-1.2	M907P	Neutral	0.001
LRP5	O75197-1.2	M907Q	Neutral	0.0
LRP5	O75197-1.2	M907R	Neutral	0.0
LRP5	O75197-1.2	M907S	Neutral	0.0
LRP5	O75197-1.2	M907T	Neutral	0.0
LRP5	O75197-1.2	M907V	Neutral	0.0
LRP5	O75197-1.2	M907W	Neutral	0.0
LRP5	O75197-1.2	M907Y	Neutral	0.0
LRP5	O75197-1.2	H908A	Neutral	0.0
LRP5	O75197-1.2	H908C	Neutral	0.0
LRP5	O75197-1.2	H908D	Neutral	0.0
LRP5	O75197-1.2	H908E	Neutral	0.0
LRP5	O75197-1.2	H908F	Neutral	0.0
LRP5	O75197-1.2	H908G	Neutral	0.0
LRP5	O75197-1.2	H908I	Neutral	0.0
LRP5	O75197-1.2	H908K	Neutral	0.0
LRP5	O75197-1.2	H908L	Neutral	0.0
LRP5	O75197-1.2	H908M	Neutral	0.0
LRP5	O75197-1.2	H908N	Neutral	0.0
LRP5	O75197-1.2	H908P	Neutral	0.0
LRP5	O75197-1.2	H908Q	Neutral	0.0
LRP5	O75197-1.2	H908R	Neutral	0.0
LRP5	O75197-1.2	H908S	Neutral	0.0
LRP5	O75197-1.2	H908T	Neutral	0.0
LRP5	O75197-1.2	H908V	Neutral	0.0
LRP5	O75197-1.2	H908W	Neutral	0.0
LRP5	O75197-1.2	H908Y	Neutral	0.0
LRP5	O75197-1.2	N909A	Neutral	0.001
LRP5	O75197-1.2	N909C	Neutral	0.002
LRP5	O75197-1.2	N909D	Neutral	0.0
LRP5	O75197-1.2	N909E	Neutral	0.0
LRP5	O75197-1.2	N909F	Neutral	0.001
LRP5	O75197-1.2	N909G	Neutral	0.0
LRP5	O75197-1.2	N909H	Neutral	0.0
LRP5	O75197-1.2	N909I	Neutral	0.001
LRP5	O75197-1.2	N909K	Neutral	0.0
LRP5	O75197-1.2	N909L	Neutral	0.001
LRP5	O75197-1.2	N909M	Neutral	0.001
LRP5	O75197-1.2	N909P	Neutral	0.001
LRP5	O75197-1.2	N909Q	Neutral	0.0
LRP5	O75197-1.2	N909R	Neutral	0.0
LRP5	O75197-1.2	N909S	Neutral	0.0
LRP5	O75197-1.2	N909T	Neutral	0.0
LRP5	O75197-1.2	N909V	Neutral	0.002
LRP5	O75197-1.2	N909W	Neutral	0.002
LRP5	O75197-1.2	N909Y	Neutral	0.001
LRP5	O75197-1.2	N910A	Pathogenic	0.503
LRP5	O75197-1.2	N910C	Pathogenic	0.634
LRP5	O75197-1.2	N910D	Neutral	0.067
LRP5	O75197-1.2	N910E	Neutral	0.196
LRP5	O75197-1.2	N910F	Neutral	0.446
LRP5	O75197-1.2	N910G	Neutral	0.122
LRP5	O75197-1.2	N910H	Neutral	0.041
LRP5	O75197-1.2	N910I	Neutral	0.447
LRP5	O75197-1.2	N910K	Neutral	0.146
LRP5	O75197-1.2	N910L	Neutral	0.47
LRP5	O75197-1.2	N910M	Neutral	0.307
LRP5	O75197-1.2	N910P	Neutral	0.421
LRP5	O75197-1.2	N910Q	Neutral	0.151
LRP5	O75197-1.2	N910R	Neutral	0.142
LRP5	O75197-1.2	N910S	Neutral	0.047
LRP5	O75197-1.2	N910T	Neutral	0.107
LRP5	O75197-1.2	N910V	Pathogenic	0.585
LRP5	O75197-1.2	N910W	Pathogenic	0.608
LRP5	O75197-1.2	N910Y	Neutral	0.355
LRP5	O75197-1.2	G911A	Neutral	0.093
LRP5	O75197-1.2	G911C	Pathogenic	0.604
LRP5	O75197-1.2	G911D	Neutral	0.165
LRP5	O75197-1.2	G911E	Neutral	0.397
LRP5	O75197-1.2	G911F	Neutral	0.407
LRP5	O75197-1.2	G911H	Pathogenic	0.505
LRP5	O75197-1.2	G911I	Pathogenic	0.677
LRP5	O75197-1.2	G911K	Neutral	0.316
LRP5	O75197-1.2	G911L	Pathogenic	0.697
LRP5	O75197-1.2	G911M	Pathogenic	0.535
LRP5	O75197-1.2	G911N	Neutral	0.07
LRP5	O75197-1.2	G911P	Neutral	0.387
LRP5	O75197-1.2	G911Q	Neutral	0.487
LRP5	O75197-1.2	G911R	Neutral	0.308
LRP5	O75197-1.2	G911S	Neutral	0.114
LRP5	O75197-1.2	G911T	Neutral	0.487
LRP5	O75197-1.2	G911V	Pathogenic	0.546
LRP5	O75197-1.2	G911W	Neutral	0.125
LRP5	O75197-1.2	G911Y	Pathogenic	0.588
LRP5	O75197-1.2	Q912A	Neutral	0.0
LRP5	O75197-1.2	Q912C	Neutral	0.002
LRP5	O75197-1.2	Q912D	Neutral	0.0
LRP5	O75197-1.2	Q912E	Neutral	0.0
LRP5	O75197-1.2	Q912F	Neutral	0.001
LRP5	O75197-1.2	Q912G	Neutral	0.001
LRP5	O75197-1.2	Q912H	Neutral	0.0
LRP5	O75197-1.2	Q912I	Neutral	0.001
LRP5	O75197-1.2	Q912K	Neutral	0.0
LRP5	O75197-1.2	Q912L	Neutral	0.0
LRP5	O75197-1.2	Q912M	Neutral	0.0
LRP5	O75197-1.2	Q912N	Neutral	0.0
LRP5	O75197-1.2	Q912P	Neutral	0.0
LRP5	O75197-1.2	Q912R	Neutral	0.0
LRP5	O75197-1.2	Q912S	Neutral	0.0
LRP5	O75197-1.2	Q912T	Neutral	0.0
LRP5	O75197-1.2	Q912V	Neutral	0.0
LRP5	O75197-1.2	Q912W	Neutral	0.0
LRP5	O75197-1.2	Q912Y	Neutral	0.0
LRP5	O75197-1.2	C913A	Pathogenic	0.993
LRP5	O75197-1.2	C913D	Pathogenic	0.999
LRP5	O75197-1.2	C913E	Pathogenic	1.0
LRP5	O75197-1.2	C913F	Pathogenic	0.999
LRP5	O75197-1.2	C913G	Pathogenic	1.0
LRP5	O75197-1.2	C913H	Pathogenic	1.0
LRP5	O75197-1.2	C913I	Pathogenic	0.997
LRP5	O75197-1.2	C913K	Pathogenic	0.999
LRP5	O75197-1.2	C913L	Pathogenic	0.997
LRP5	O75197-1.2	C913M	Pathogenic	0.998
LRP5	O75197-1.2	C913N	Pathogenic	0.999
LRP5	O75197-1.2	C913P	Pathogenic	1.0
LRP5	O75197-1.2	C913Q	Pathogenic	1.0
LRP5	O75197-1.2	C913R	Pathogenic	0.999
LRP5	O75197-1.2	C913S	Pathogenic	0.997
LRP5	O75197-1.2	C913T	Pathogenic	0.998
LRP5	O75197-1.2	C913V	Pathogenic	0.998
LRP5	O75197-1.2	C913W	Pathogenic	0.999
LRP5	O75197-1.2	C913Y	Pathogenic	1.0
LRP5	O75197-1.2	G914A	Neutral	0.0
LRP5	O75197-1.2	G914C	Neutral	0.005
LRP5	O75197-1.2	G914D	Neutral	0.001
LRP5	O75197-1.2	G914E	Neutral	0.002
LRP5	O75197-1.2	G914F	Neutral	0.002
LRP5	O75197-1.2	G914H	Neutral	0.003
LRP5	O75197-1.2	G914I	Neutral	0.007
LRP5	O75197-1.2	G914K	Neutral	0.001
LRP5	O75197-1.2	G914L	Neutral	0.007
LRP5	O75197-1.2	G914M	Neutral	0.004
LRP5	O75197-1.2	G914N	Neutral	0.0
LRP5	O75197-1.2	G914P	Neutral	0.002
LRP5	O75197-1.2	G914Q	Neutral	0.003
LRP5	O75197-1.2	G914R	Neutral	0.001
LRP5	O75197-1.2	G914S	Neutral	0.0
LRP5	O75197-1.2	G914T	Neutral	0.003
LRP5	O75197-1.2	G914V	Neutral	0.004
LRP5	O75197-1.2	G914W	Neutral	0.0
LRP5	O75197-1.2	G914Y	Neutral	0.005
LRP5	O75197-1.2	Q915A	Neutral	0.008
LRP5	O75197-1.2	Q915C	Neutral	0.04
LRP5	O75197-1.2	Q915D	Neutral	0.003
LRP5	O75197-1.2	Q915E	Neutral	0.0
LRP5	O75197-1.2	Q915F	Neutral	0.02
LRP5	O75197-1.2	Q915G	Neutral	0.03
LRP5	O75197-1.2	Q915H	Neutral	0.003
LRP5	O75197-1.2	Q915I	Neutral	0.02
LRP5	O75197-1.2	Q915K	Neutral	0.001
LRP5	O75197-1.2	Q915L	Neutral	0.007
LRP5	O75197-1.2	Q915M	Neutral	0.001
LRP5	O75197-1.2	Q915N	Neutral	0.003
LRP5	O75197-1.2	Q915P	Neutral	0.006
LRP5	O75197-1.2	Q915R	Neutral	0.001
LRP5	O75197-1.2	Q915S	Neutral	0.004
LRP5	O75197-1.2	Q915T	Neutral	0.009
LRP5	O75197-1.2	Q915V	Neutral	0.011
LRP5	O75197-1.2	Q915W	Neutral	0.004
LRP5	O75197-1.2	Q915Y	Neutral	0.005
LRP5	O75197-1.2	L916A	Neutral	0.097
LRP5	O75197-1.2	L916C	Neutral	0.168
LRP5	O75197-1.2	L916D	Pathogenic	0.544
LRP5	O75197-1.2	L916E	Neutral	0.313
LRP5	O75197-1.2	L916F	Neutral	0.109
LRP5	O75197-1.2	L916G	Pathogenic	0.689
LRP5	O75197-1.2	L916H	Neutral	0.479
LRP5	O75197-1.2	L916I	Neutral	0.013
LRP5	O75197-1.2	L916K	Neutral	0.099
LRP5	O75197-1.2	L916M	Neutral	0.009
LRP5	O75197-1.2	L916N	Neutral	0.315
LRP5	O75197-1.2	L916P	Pathogenic	0.597
LRP5	O75197-1.2	L916Q	Neutral	0.18
LRP5	O75197-1.2	L916R	Neutral	0.096
LRP5	O75197-1.2	L916S	Neutral	0.195
LRP5	O75197-1.2	L916T	Neutral	0.096
LRP5	O75197-1.2	L916V	Neutral	0.027
LRP5	O75197-1.2	L916W	Neutral	0.416
LRP5	O75197-1.2	L916Y	Neutral	0.17
LRP5	O75197-1.2	C917A	Pathogenic	0.993
LRP5	O75197-1.2	C917D	Pathogenic	0.999
LRP5	O75197-1.2	C917E	Pathogenic	1.0
LRP5	O75197-1.2	C917F	Pathogenic	0.999
LRP5	O75197-1.2	C917G	Pathogenic	1.0
LRP5	O75197-1.2	C917H	Pathogenic	1.0
LRP5	O75197-1.2	C917I	Pathogenic	0.997
LRP5	O75197-1.2	C917K	Pathogenic	0.999
LRP5	O75197-1.2	C917L	Pathogenic	0.997
LRP5	O75197-1.2	C917M	Pathogenic	0.998
LRP5	O75197-1.2	C917N	Pathogenic	0.999
LRP5	O75197-1.2	C917P	Pathogenic	1.0
LRP5	O75197-1.2	C917Q	Pathogenic	1.0
LRP5	O75197-1.2	C917R	Pathogenic	0.999
LRP5	O75197-1.2	C917S	Pathogenic	0.997
LRP5	O75197-1.2	C917T	Pathogenic	0.998
LRP5	O75197-1.2	C917V	Pathogenic	0.998
LRP5	O75197-1.2	C917W	Pathogenic	0.999
LRP5	O75197-1.2	C917Y	Pathogenic	1.0
LRP5	O75197-1.2	L918A	Neutral	0.026
LRP5	O75197-1.2	L918C	Neutral	0.048
LRP5	O75197-1.2	L918D	Neutral	0.23
LRP5	O75197-1.2	L918E	Neutral	0.102
LRP5	O75197-1.2	L918F	Neutral	0.03
LRP5	O75197-1.2	L918G	Neutral	0.357
LRP5	O75197-1.2	L918H	Neutral	0.187
LRP5	O75197-1.2	L918I	Neutral	0.003
LRP5	O75197-1.2	L918K	Neutral	0.027
LRP5	O75197-1.2	L918M	Neutral	0.002
LRP5	O75197-1.2	L918N	Neutral	0.103
LRP5	O75197-1.2	L918P	Neutral	0.271
LRP5	O75197-1.2	L918Q	Neutral	0.052
LRP5	O75197-1.2	L918R	Neutral	0.026
LRP5	O75197-1.2	L918S	Neutral	0.057
LRP5	O75197-1.2	L918T	Neutral	0.026
LRP5	O75197-1.2	L918V	Neutral	0.007
LRP5	O75197-1.2	L918W	Neutral	0.151
LRP5	O75197-1.2	L918Y	Neutral	0.049
LRP5	O75197-1.2	A919C	Neutral	0.078
LRP5	O75197-1.2	A919D	Neutral	0.352
LRP5	O75197-1.2	A919E	Neutral	0.163
LRP5	O75197-1.2	A919F	Neutral	0.261
LRP5	O75197-1.2	A919G	Neutral	0.105
LRP5	O75197-1.2	A919H	Pathogenic	0.538
LRP5	O75197-1.2	A919I	Neutral	0.104
LRP5	O75197-1.2	A919K	Neutral	0.12
LRP5	O75197-1.2	A919L	Neutral	0.113
LRP5	O75197-1.2	A919M	Neutral	0.163
LRP5	O75197-1.2	A919N	Neutral	0.385
LRP5	O75197-1.2	A919P	Neutral	0.245
LRP5	O75197-1.2	A919Q	Neutral	0.22
LRP5	O75197-1.2	A919R	Neutral	0.117
LRP5	O75197-1.2	A919S	Neutral	0.037
LRP5	O75197-1.2	A919T	Neutral	0.128
LRP5	O75197-1.2	A919V	Neutral	0.063
LRP5	O75197-1.2	A919W	Neutral	0.404
LRP5	O75197-1.2	A919Y	Neutral	0.423
LRP5	O75197-1.2	I920A	Neutral	0.0
LRP5	O75197-1.2	I920C	Neutral	0.0
LRP5	O75197-1.2	I920D	Neutral	0.0
LRP5	O75197-1.2	I920E	Neutral	0.0
LRP5	O75197-1.2	I920F	Neutral	0.0
LRP5	O75197-1.2	I920G	Neutral	0.001
LRP5	O75197-1.2	I920H	Neutral	0.0
LRP5	O75197-1.2	I920K	Neutral	0.0
LRP5	O75197-1.2	I920L	Neutral	0.0
LRP5	O75197-1.2	I920M	Neutral	0.0
LRP5	O75197-1.2	I920N	Neutral	0.0
LRP5	O75197-1.2	I920P	Neutral	0.0
LRP5	O75197-1.2	I920Q	Neutral	0.0
LRP5	O75197-1.2	I920R	Neutral	0.0
LRP5	O75197-1.2	I920S	Neutral	0.0
LRP5	O75197-1.2	I920T	Neutral	0.0
LRP5	O75197-1.2	I920V	Neutral	0.0
LRP5	O75197-1.2	I920W	Neutral	0.001
LRP5	O75197-1.2	I920Y	Neutral	0.0
LRP5	O75197-1.2	P921A	Neutral	0.157
LRP5	O75197-1.2	P921C	Pathogenic	0.669
LRP5	O75197-1.2	P921D	Neutral	0.068
LRP5	O75197-1.2	P921E	Neutral	0.074
LRP5	O75197-1.2	P921F	Pathogenic	0.737
LRP5	O75197-1.2	P921G	Neutral	0.294
LRP5	O75197-1.2	P921H	Neutral	0.324
LRP5	O75197-1.2	P921I	Neutral	0.48
LRP5	O75197-1.2	P921K	Neutral	0.053
LRP5	O75197-1.2	P921L	Pathogenic	0.503
LRP5	O75197-1.2	P921M	Neutral	0.336
LRP5	O75197-1.2	P921N	Neutral	0.205
LRP5	O75197-1.2	P921Q	Neutral	0.104
LRP5	O75197-1.2	P921R	Neutral	0.142
LRP5	O75197-1.2	P921S	Neutral	0.121
LRP5	O75197-1.2	P921T	Neutral	0.155
LRP5	O75197-1.2	P921V	Neutral	0.346
LRP5	O75197-1.2	P921W	Pathogenic	0.639
LRP5	O75197-1.2	P921Y	Pathogenic	0.656
LRP5	O75197-1.2	G922A	Neutral	0.0
LRP5	O75197-1.2	G922C	Neutral	0.002
LRP5	O75197-1.2	G922D	Neutral	0.0
LRP5	O75197-1.2	G922E	Neutral	0.001
LRP5	O75197-1.2	G922F	Neutral	0.001
LRP5	O75197-1.2	G922H	Neutral	0.001
LRP5	O75197-1.2	G922I	Neutral	0.003
LRP5	O75197-1.2	G922K	Neutral	0.001
LRP5	O75197-1.2	G922L	Neutral	0.003
LRP5	O75197-1.2	G922M	Neutral	0.001
LRP5	O75197-1.2	G922N	Neutral	0.0
LRP5	O75197-1.2	G922P	Neutral	0.001
LRP5	O75197-1.2	G922Q	Neutral	0.001
LRP5	O75197-1.2	G922R	Neutral	0.001
LRP5	O75197-1.2	G922S	Neutral	0.0
LRP5	O75197-1.2	G922T	Neutral	0.001
LRP5	O75197-1.2	G922V	Neutral	0.002
LRP5	O75197-1.2	G922W	Neutral	0.0
LRP5	O75197-1.2	G922Y	Neutral	0.002
LRP5	O75197-1.2	G923A	Neutral	0.005
LRP5	O75197-1.2	G923C	Neutral	0.071
LRP5	O75197-1.2	G923D	Neutral	0.01
LRP5	O75197-1.2	G923E	Neutral	0.032
LRP5	O75197-1.2	G923F	Neutral	0.033
LRP5	O75197-1.2	G923H	Neutral	0.048
LRP5	O75197-1.2	G923I	Neutral	0.095
LRP5	O75197-1.2	G923K	Neutral	0.022
LRP5	O75197-1.2	G923L	Neutral	0.103
LRP5	O75197-1.2	G923M	Neutral	0.054
LRP5	O75197-1.2	G923N	Neutral	0.004
LRP5	O75197-1.2	G923P	Neutral	0.03
LRP5	O75197-1.2	G923Q	Neutral	0.045
LRP5	O75197-1.2	G923R	Neutral	0.022
LRP5	O75197-1.2	G923S	Neutral	0.006
LRP5	O75197-1.2	G923T	Neutral	0.045
LRP5	O75197-1.2	G923V	Neutral	0.056
LRP5	O75197-1.2	G923W	Neutral	0.007
LRP5	O75197-1.2	G923Y	Neutral	0.066
LRP5	O75197-1.2	H924A	Neutral	0.001
LRP5	O75197-1.2	H924C	Neutral	0.001
LRP5	O75197-1.2	H924D	Neutral	0.0
LRP5	O75197-1.2	H924E	Neutral	0.0
LRP5	O75197-1.2	H924F	Neutral	0.0
LRP5	O75197-1.2	H924G	Neutral	0.001
LRP5	O75197-1.2	H924I	Neutral	0.0
LRP5	O75197-1.2	H924K	Neutral	0.0
LRP5	O75197-1.2	H924L	Neutral	0.001
LRP5	O75197-1.2	H924M	Neutral	0.0
LRP5	O75197-1.2	H924N	Neutral	0.0
LRP5	O75197-1.2	H924P	Neutral	0.0
LRP5	O75197-1.2	H924Q	Neutral	0.0
LRP5	O75197-1.2	H924R	Neutral	0.0
LRP5	O75197-1.2	H924S	Neutral	0.0
LRP5	O75197-1.2	H924T	Neutral	0.001
LRP5	O75197-1.2	H924V	Neutral	0.001
LRP5	O75197-1.2	H924W	Neutral	0.0
LRP5	O75197-1.2	H924Y	Neutral	0.0
LRP5	O75197-1.2	R925A	Neutral	0.0
LRP5	O75197-1.2	R925C	Neutral	0.0
LRP5	O75197-1.2	R925D	Neutral	0.0
LRP5	O75197-1.2	R925E	Neutral	0.0
LRP5	O75197-1.2	R925F	Neutral	0.0
LRP5	O75197-1.2	R925G	Neutral	0.0
LRP5	O75197-1.2	R925H	Neutral	0.0
LRP5	O75197-1.2	R925I	Neutral	0.0
LRP5	O75197-1.2	R925K	Neutral	0.0
LRP5	O75197-1.2	R925L	Neutral	0.0
LRP5	O75197-1.2	R925M	Neutral	0.0
LRP5	O75197-1.2	R925N	Neutral	0.0
LRP5	O75197-1.2	R925P	Neutral	0.0
LRP5	O75197-1.2	R925Q	Neutral	0.0
LRP5	O75197-1.2	R925S	Neutral	0.0
LRP5	O75197-1.2	R925T	Neutral	0.0
LRP5	O75197-1.2	R925V	Neutral	0.0
LRP5	O75197-1.2	R925W	Neutral	0.0
LRP5	O75197-1.2	R925Y	Neutral	0.0
LRP5	O75197-1.2	C926A	Pathogenic	0.992
LRP5	O75197-1.2	C926D	Pathogenic	0.999
LRP5	O75197-1.2	C926E	Pathogenic	1.0
LRP5	O75197-1.2	C926F	Pathogenic	0.999
LRP5	O75197-1.2	C926G	Pathogenic	1.0
LRP5	O75197-1.2	C926H	Pathogenic	1.0
LRP5	O75197-1.2	C926I	Pathogenic	0.997
LRP5	O75197-1.2	C926K	Pathogenic	0.999
LRP5	O75197-1.2	C926L	Pathogenic	0.997
LRP5	O75197-1.2	C926M	Pathogenic	0.998
LRP5	O75197-1.2	C926N	Pathogenic	0.999
LRP5	O75197-1.2	C926P	Pathogenic	1.0
LRP5	O75197-1.2	C926Q	Pathogenic	1.0
LRP5	O75197-1.2	C926R	Pathogenic	0.999
LRP5	O75197-1.2	C926S	Pathogenic	0.997
LRP5	O75197-1.2	C926T	Pathogenic	0.997
LRP5	O75197-1.2	C926V	Pathogenic	0.998
LRP5	O75197-1.2	C926W	Pathogenic	0.998
LRP5	O75197-1.2	C926Y	Pathogenic	1.0
LRP5	O75197-1.2	G927A	Neutral	0.0
LRP5	O75197-1.2	G927C	Neutral	0.006
LRP5	O75197-1.2	G927D	Neutral	0.001
LRP5	O75197-1.2	G927E	Neutral	0.002
LRP5	O75197-1.2	G927F	Neutral	0.003
LRP5	O75197-1.2	G927H	Neutral	0.004
LRP5	O75197-1.2	G927I	Neutral	0.008
LRP5	O75197-1.2	G927K	Neutral	0.002
LRP5	O75197-1.2	G927L	Neutral	0.009
LRP5	O75197-1.2	G927M	Neutral	0.004
LRP5	O75197-1.2	G927N	Neutral	0.0
LRP5	O75197-1.2	G927P	Neutral	0.002
LRP5	O75197-1.2	G927Q	Neutral	0.004
LRP5	O75197-1.2	G927R	Neutral	0.002
LRP5	O75197-1.2	G927S	Neutral	0.0
LRP5	O75197-1.2	G927T	Neutral	0.004
LRP5	O75197-1.2	G927V	Neutral	0.005
LRP5	O75197-1.2	G927W	Neutral	0.001
LRP5	O75197-1.2	G927Y	Neutral	0.005
LRP5	O75197-1.2	C928A	Pathogenic	0.994
LRP5	O75197-1.2	C928D	Pathogenic	0.999
LRP5	O75197-1.2	C928E	Pathogenic	1.0
LRP5	O75197-1.2	C928F	Pathogenic	0.999
LRP5	O75197-1.2	C928G	Pathogenic	1.0
LRP5	O75197-1.2	C928H	Pathogenic	1.0
LRP5	O75197-1.2	C928I	Pathogenic	0.998
LRP5	O75197-1.2	C928K	Pathogenic	0.999
LRP5	O75197-1.2	C928L	Pathogenic	0.998
LRP5	O75197-1.2	C928M	Pathogenic	0.999
LRP5	O75197-1.2	C928N	Pathogenic	1.0
LRP5	O75197-1.2	C928P	Pathogenic	1.0
LRP5	O75197-1.2	C928Q	Pathogenic	1.0
LRP5	O75197-1.2	C928R	Pathogenic	0.999
LRP5	O75197-1.2	C928S	Pathogenic	0.997
LRP5	O75197-1.2	C928T	Pathogenic	0.998
LRP5	O75197-1.2	C928V	Pathogenic	0.999
LRP5	O75197-1.2	C928W	Pathogenic	0.999
LRP5	O75197-1.2	C928Y	Pathogenic	1.0
LRP5	O75197-1.2	A929C	Neutral	0.002
LRP5	O75197-1.2	A929D	Neutral	0.011
LRP5	O75197-1.2	A929E	Neutral	0.004
LRP5	O75197-1.2	A929F	Neutral	0.007
LRP5	O75197-1.2	A929G	Neutral	0.002
LRP5	O75197-1.2	A929H	Neutral	0.023
LRP5	O75197-1.2	A929I	Neutral	0.002
LRP5	O75197-1.2	A929K	Neutral	0.003
LRP5	O75197-1.2	A929L	Neutral	0.003
LRP5	O75197-1.2	A929M	Neutral	0.004
LRP5	O75197-1.2	A929N	Neutral	0.012
LRP5	O75197-1.2	A929P	Neutral	0.006
LRP5	O75197-1.2	A929Q	Neutral	0.006
LRP5	O75197-1.2	A929R	Neutral	0.003
LRP5	O75197-1.2	A929S	Neutral	0.001
LRP5	O75197-1.2	A929T	Neutral	0.003
LRP5	O75197-1.2	A929V	Neutral	0.001
LRP5	O75197-1.2	A929W	Neutral	0.013
LRP5	O75197-1.2	A929Y	Neutral	0.015
LRP5	O75197-1.2	S930A	Neutral	0.0
LRP5	O75197-1.2	S930C	Neutral	0.0
LRP5	O75197-1.2	S930D	Neutral	0.0
LRP5	O75197-1.2	S930E	Neutral	0.0
LRP5	O75197-1.2	S930F	Neutral	0.0
LRP5	O75197-1.2	S930G	Neutral	0.0
LRP5	O75197-1.2	S930H	Neutral	0.001
LRP5	O75197-1.2	S930I	Neutral	0.0
LRP5	O75197-1.2	S930K	Neutral	0.0
LRP5	O75197-1.2	S930L	Neutral	0.0
LRP5	O75197-1.2	S930M	Neutral	0.0
LRP5	O75197-1.2	S930N	Neutral	0.0
LRP5	O75197-1.2	S930P	Neutral	0.0
LRP5	O75197-1.2	S930Q	Neutral	0.0
LRP5	O75197-1.2	S930R	Neutral	0.0
LRP5	O75197-1.2	S930T	Neutral	0.0
LRP5	O75197-1.2	S930V	Neutral	0.001
LRP5	O75197-1.2	S930W	Neutral	0.001
LRP5	O75197-1.2	S930Y	Neutral	0.001
LRP5	O75197-1.2	H931A	Pathogenic	0.815
LRP5	O75197-1.2	H931C	Pathogenic	0.883
LRP5	O75197-1.2	H931D	Neutral	0.441
LRP5	O75197-1.2	H931E	Neutral	0.231
LRP5	O75197-1.2	H931F	Neutral	0.29
LRP5	O75197-1.2	H931G	Pathogenic	0.817
LRP5	O75197-1.2	H931I	Pathogenic	0.791
LRP5	O75197-1.2	H931K	Neutral	0.397
LRP5	O75197-1.2	H931L	Pathogenic	0.806
LRP5	O75197-1.2	H931M	Pathogenic	0.675
LRP5	O75197-1.2	H931N	Neutral	0.091
LRP5	O75197-1.2	H931P	Pathogenic	0.76
LRP5	O75197-1.2	H931Q	Neutral	0.305
LRP5	O75197-1.2	H931R	Neutral	0.173
LRP5	O75197-1.2	H931S	Pathogenic	0.596
LRP5	O75197-1.2	H931T	Pathogenic	0.828
LRP5	O75197-1.2	H931V	Pathogenic	0.864
LRP5	O75197-1.2	H931W	Neutral	0.44
LRP5	O75197-1.2	H931Y	Neutral	0.029
LRP5	O75197-1.2	Y932A	Neutral	0.244
LRP5	O75197-1.2	Y932C	Neutral	0.369
LRP5	O75197-1.2	Y932D	Neutral	0.281
LRP5	O75197-1.2	Y932E	Neutral	0.129
LRP5	O75197-1.2	Y932F	Neutral	0.001
LRP5	O75197-1.2	Y932G	Neutral	0.42
LRP5	O75197-1.2	Y932H	Neutral	0.003
LRP5	O75197-1.2	Y932I	Neutral	0.089
LRP5	O75197-1.2	Y932K	Neutral	0.102
LRP5	O75197-1.2	Y932L	Neutral	0.097
LRP5	O75197-1.2	Y932M	Neutral	0.141
LRP5	O75197-1.2	Y932N	Neutral	0.131
LRP5	O75197-1.2	Y932P	Pathogenic	0.596
LRP5	O75197-1.2	Y932Q	Neutral	0.067
LRP5	O75197-1.2	Y932R	Neutral	0.1
LRP5	O75197-1.2	Y932S	Neutral	0.193
LRP5	O75197-1.2	Y932T	Neutral	0.244
LRP5	O75197-1.2	Y932V	Neutral	0.139
LRP5	O75197-1.2	Y932W	Neutral	0.002
LRP5	O75197-1.2	T933A	Neutral	0.0
LRP5	O75197-1.2	T933C	Neutral	0.0
LRP5	O75197-1.2	T933D	Neutral	0.0
LRP5	O75197-1.2	T933E	Neutral	0.0
LRP5	O75197-1.2	T933F	Neutral	0.0
LRP5	O75197-1.2	T933G	Neutral	0.001
LRP5	O75197-1.2	T933H	Neutral	0.001
LRP5	O75197-1.2	T933I	Neutral	0.0
LRP5	O75197-1.2	T933K	Neutral	0.0
LRP5	O75197-1.2	T933L	Neutral	0.0
LRP5	O75197-1.2	T933M	Neutral	0.0
LRP5	O75197-1.2	T933N	Neutral	0.0
LRP5	O75197-1.2	T933P	Neutral	0.0
LRP5	O75197-1.2	T933Q	Neutral	0.0
LRP5	O75197-1.2	T933R	Neutral	0.0
LRP5	O75197-1.2	T933S	Neutral	0.0
LRP5	O75197-1.2	T933V	Neutral	0.0
LRP5	O75197-1.2	T933W	Neutral	0.0
LRP5	O75197-1.2	T933Y	Neutral	0.001
LRP5	O75197-1.2	L934A	Neutral	0.07
LRP5	O75197-1.2	L934C	Neutral	0.124
LRP5	O75197-1.2	L934D	Neutral	0.457
LRP5	O75197-1.2	L934E	Neutral	0.243
LRP5	O75197-1.2	L934F	Neutral	0.079
LRP5	O75197-1.2	L934G	Pathogenic	0.61
LRP5	O75197-1.2	L934H	Neutral	0.393
LRP5	O75197-1.2	L934I	Neutral	0.009
LRP5	O75197-1.2	L934K	Neutral	0.072
LRP5	O75197-1.2	L934M	Neutral	0.007
LRP5	O75197-1.2	L934N	Neutral	0.245
LRP5	O75197-1.2	L934P	Pathogenic	0.511
LRP5	O75197-1.2	L934Q	Neutral	0.134
LRP5	O75197-1.2	L934R	Neutral	0.07
LRP5	O75197-1.2	L934S	Neutral	0.145
LRP5	O75197-1.2	L934T	Neutral	0.07
LRP5	O75197-1.2	L934V	Neutral	0.019
LRP5	O75197-1.2	L934W	Neutral	0.334
LRP5	O75197-1.2	L934Y	Neutral	0.126
LRP5	O75197-1.2	D935A	Neutral	0.0
LRP5	O75197-1.2	D935C	Neutral	0.001
LRP5	O75197-1.2	D935E	Neutral	0.0
LRP5	O75197-1.2	D935F	Neutral	0.0
LRP5	O75197-1.2	D935G	Neutral	0.0
LRP5	O75197-1.2	D935H	Neutral	0.0
LRP5	O75197-1.2	D935I	Neutral	0.0
LRP5	O75197-1.2	D935K	Neutral	0.0
LRP5	O75197-1.2	D935L	Neutral	0.001
LRP5	O75197-1.2	D935M	Neutral	0.001
LRP5	O75197-1.2	D935N	Neutral	0.0
LRP5	O75197-1.2	D935P	Neutral	0.0
LRP5	O75197-1.2	D935Q	Neutral	0.0
LRP5	O75197-1.2	D935R	Neutral	0.001
LRP5	O75197-1.2	D935S	Neutral	0.0
LRP5	O75197-1.2	D935T	Neutral	0.0
LRP5	O75197-1.2	D935V	Neutral	0.001
LRP5	O75197-1.2	D935W	Neutral	0.001
LRP5	O75197-1.2	D935Y	Neutral	0.001
LRP5	O75197-1.2	P936A	Neutral	0.0
LRP5	O75197-1.2	P936C	Neutral	0.001
LRP5	O75197-1.2	P936D	Neutral	0.0
LRP5	O75197-1.2	P936E	Neutral	0.0
LRP5	O75197-1.2	P936F	Neutral	0.001
LRP5	O75197-1.2	P936G	Neutral	0.0
LRP5	O75197-1.2	P936H	Neutral	0.0
LRP5	O75197-1.2	P936I	Neutral	0.0
LRP5	O75197-1.2	P936K	Neutral	0.0
LRP5	O75197-1.2	P936L	Neutral	0.0
LRP5	O75197-1.2	P936M	Neutral	0.0
LRP5	O75197-1.2	P936N	Neutral	0.0
LRP5	O75197-1.2	P936Q	Neutral	0.0
LRP5	O75197-1.2	P936R	Neutral	0.0
LRP5	O75197-1.2	P936S	Neutral	0.0
LRP5	O75197-1.2	P936T	Neutral	0.0
LRP5	O75197-1.2	P936V	Neutral	0.0
LRP5	O75197-1.2	P936W	Neutral	0.001
LRP5	O75197-1.2	P936Y	Neutral	0.001
LRP5	O75197-1.2	S937A	Neutral	0.0
LRP5	O75197-1.2	S937C	Neutral	0.0
LRP5	O75197-1.2	S937D	Neutral	0.0
LRP5	O75197-1.2	S937E	Neutral	0.0
LRP5	O75197-1.2	S937F	Neutral	0.0
LRP5	O75197-1.2	S937G	Neutral	0.0
LRP5	O75197-1.2	S937H	Neutral	0.0
LRP5	O75197-1.2	S937I	Neutral	0.0
LRP5	O75197-1.2	S937K	Neutral	0.0
LRP5	O75197-1.2	S937L	Neutral	0.0
LRP5	O75197-1.2	S937M	Neutral	0.0
LRP5	O75197-1.2	S937N	Neutral	0.0
LRP5	O75197-1.2	S937P	Neutral	0.0
LRP5	O75197-1.2	S937Q	Neutral	0.0
LRP5	O75197-1.2	S937R	Neutral	0.0
LRP5	O75197-1.2	S937T	Neutral	0.0
LRP5	O75197-1.2	S937V	Neutral	0.0
LRP5	O75197-1.2	S937W	Neutral	0.0
LRP5	O75197-1.2	S937Y	Neutral	0.0
LRP5	O75197-1.2	S938A	Neutral	0.0
LRP5	O75197-1.2	S938C	Neutral	0.001
LRP5	O75197-1.2	S938D	Neutral	0.0
LRP5	O75197-1.2	S938E	Neutral	0.0
LRP5	O75197-1.2	S938F	Neutral	0.001
LRP5	O75197-1.2	S938G	Neutral	0.0
LRP5	O75197-1.2	S938H	Neutral	0.001
LRP5	O75197-1.2	S938I	Neutral	0.001
LRP5	O75197-1.2	S938K	Neutral	0.0
LRP5	O75197-1.2	S938L	Neutral	0.001
LRP5	O75197-1.2	S938M	Neutral	0.0
LRP5	O75197-1.2	S938N	Neutral	0.0
LRP5	O75197-1.2	S938P	Neutral	0.001
LRP5	O75197-1.2	S938Q	Neutral	0.0
LRP5	O75197-1.2	S938R	Neutral	0.001
LRP5	O75197-1.2	S938T	Neutral	0.0
LRP5	O75197-1.2	S938V	Neutral	0.001
LRP5	O75197-1.2	S938W	Neutral	0.002
LRP5	O75197-1.2	S938Y	Neutral	0.002
LRP5	O75197-1.2	R939A	Neutral	0.006
LRP5	O75197-1.2	R939C	Neutral	0.032
LRP5	O75197-1.2	R939D	Neutral	0.049
LRP5	O75197-1.2	R939E	Neutral	0.005
LRP5	O75197-1.2	R939F	Neutral	0.017
LRP5	O75197-1.2	R939G	Neutral	0.024
LRP5	O75197-1.2	R939H	Neutral	0.003
LRP5	O75197-1.2	R939I	Neutral	0.016
LRP5	O75197-1.2	R939K	Neutral	0.001
LRP5	O75197-1.2	R939L	Neutral	0.006
LRP5	O75197-1.2	R939M	Neutral	0.003
LRP5	O75197-1.2	R939N	Neutral	0.005
LRP5	O75197-1.2	R939P	Neutral	0.013
LRP5	O75197-1.2	R939Q	Neutral	0.001
LRP5	O75197-1.2	R939S	Neutral	0.009
LRP5	O75197-1.2	R939T	Neutral	0.007
LRP5	O75197-1.2	R939V	Neutral	0.027
LRP5	O75197-1.2	R939W	Neutral	0.011
LRP5	O75197-1.2	R939Y	Neutral	0.012
LRP5	O75197-1.2	N940A	Neutral	0.017
LRP5	O75197-1.2	N940C	Neutral	0.029
LRP5	O75197-1.2	N940D	Neutral	0.001
LRP5	O75197-1.2	N940E	Neutral	0.004
LRP5	O75197-1.2	N940F	Neutral	0.014
LRP5	O75197-1.2	N940G	Neutral	0.002
LRP5	O75197-1.2	N940H	Neutral	0.001
LRP5	O75197-1.2	N940I	Neutral	0.014
LRP5	O75197-1.2	N940K	Neutral	0.003
LRP5	O75197-1.2	N940L	Neutral	0.015
LRP5	O75197-1.2	N940M	Neutral	0.008
LRP5	O75197-1.2	N940P	Neutral	0.012
LRP5	O75197-1.2	N940Q	Neutral	0.003
LRP5	O75197-1.2	N940R	Neutral	0.003
LRP5	O75197-1.2	N940S	Neutral	0.001
LRP5	O75197-1.2	N940T	Neutral	0.002
LRP5	O75197-1.2	N940V	Neutral	0.024
LRP5	O75197-1.2	N940W	Neutral	0.026
LRP5	O75197-1.2	N940Y	Neutral	0.009
LRP5	O75197-1.2	C941A	Pathogenic	0.994
LRP5	O75197-1.2	C941D	Pathogenic	0.999
LRP5	O75197-1.2	C941E	Pathogenic	1.0
LRP5	O75197-1.2	C941F	Pathogenic	0.999
LRP5	O75197-1.2	C941G	Pathogenic	1.0
LRP5	O75197-1.2	C941H	Pathogenic	1.0
LRP5	O75197-1.2	C941I	Pathogenic	0.998
LRP5	O75197-1.2	C941K	Pathogenic	0.999
LRP5	O75197-1.2	C941L	Pathogenic	0.998
LRP5	O75197-1.2	C941M	Pathogenic	0.999
LRP5	O75197-1.2	C941N	Pathogenic	1.0
LRP5	O75197-1.2	C941P	Pathogenic	1.0
LRP5	O75197-1.2	C941Q	Pathogenic	1.0
LRP5	O75197-1.2	C941R	Pathogenic	0.999
LRP5	O75197-1.2	C941S	Pathogenic	0.997
LRP5	O75197-1.2	C941T	Pathogenic	0.998
LRP5	O75197-1.2	C941V	Pathogenic	0.999
LRP5	O75197-1.2	C941W	Pathogenic	0.999
LRP5	O75197-1.2	C941Y	Pathogenic	1.0
LRP5	O75197-1.2	S942A	Neutral	0.001
LRP5	O75197-1.2	S942C	Neutral	0.007
LRP5	O75197-1.2	S942D	Neutral	0.003
LRP5	O75197-1.2	S942E	Neutral	0.003
LRP5	O75197-1.2	S942F	Neutral	0.01
LRP5	O75197-1.2	S942G	Neutral	0.006
LRP5	O75197-1.2	S942H	Neutral	0.015
LRP5	O75197-1.2	S942I	Neutral	0.01
LRP5	O75197-1.2	S942K	Neutral	0.002
LRP5	O75197-1.2	S942L	Neutral	0.011
LRP5	O75197-1.2	S942M	Neutral	0.005
LRP5	O75197-1.2	S942N	Neutral	0.001
LRP5	O75197-1.2	S942P	Neutral	0.009
LRP5	O75197-1.2	S942Q	Neutral	0.005
LRP5	O75197-1.2	S942R	Neutral	0.007
LRP5	O75197-1.2	S942T	Neutral	0.001
LRP5	O75197-1.2	S942V	Neutral	0.017
LRP5	O75197-1.2	S942W	Neutral	0.019
LRP5	O75197-1.2	S942Y	Neutral	0.02
LRP5	O75197-1.2	P943A	Neutral	0.001
LRP5	O75197-1.2	P943C	Neutral	0.006
LRP5	O75197-1.2	P943D	Neutral	0.0
LRP5	O75197-1.2	P943E	Neutral	0.0
LRP5	O75197-1.2	P943F	Neutral	0.008
LRP5	O75197-1.2	P943G	Neutral	0.001
LRP5	O75197-1.2	P943H	Neutral	0.001
LRP5	O75197-1.2	P943I	Neutral	0.003
LRP5	O75197-1.2	P943K	Neutral	0.0
LRP5	O75197-1.2	P943L	Neutral	0.003
LRP5	O75197-1.2	P943M	Neutral	0.001
LRP5	O75197-1.2	P943N	Neutral	0.001
LRP5	O75197-1.2	P943Q	Neutral	0.0
LRP5	O75197-1.2	P943R	Neutral	0.0
LRP5	O75197-1.2	P943S	Neutral	0.0
LRP5	O75197-1.2	P943T	Neutral	0.001
LRP5	O75197-1.2	P943V	Neutral	0.001
LRP5	O75197-1.2	P943W	Neutral	0.005
LRP5	O75197-1.2	P943Y	Neutral	0.005
LRP5	O75197-1.2	P944A	Neutral	0.334
LRP5	O75197-1.2	P944C	Pathogenic	0.845
LRP5	O75197-1.2	P944D	Neutral	0.165
LRP5	O75197-1.2	P944E	Neutral	0.178
LRP5	O75197-1.2	P944F	Pathogenic	0.883
LRP5	O75197-1.2	P944G	Pathogenic	0.529
LRP5	O75197-1.2	P944H	Pathogenic	0.564
LRP5	O75197-1.2	P944I	Pathogenic	0.714
LRP5	O75197-1.2	P944K	Neutral	0.132
LRP5	O75197-1.2	P944L	Pathogenic	0.732
LRP5	O75197-1.2	P944M	Pathogenic	0.577
LRP5	O75197-1.2	P944N	Neutral	0.41
LRP5	O75197-1.2	P944Q	Neutral	0.238
LRP5	O75197-1.2	P944R	Neutral	0.308
LRP5	O75197-1.2	P944S	Neutral	0.271
LRP5	O75197-1.2	P944T	Neutral	0.331
LRP5	O75197-1.2	P944V	Pathogenic	0.588
LRP5	O75197-1.2	P944W	Pathogenic	0.827
LRP5	O75197-1.2	P944Y	Pathogenic	0.837
LRP5	O75197-1.2	T945A	Neutral	0.174
LRP5	O75197-1.2	T945C	Neutral	0.265
LRP5	O75197-1.2	T945D	Neutral	0.217
LRP5	O75197-1.2	T945E	Neutral	0.234
LRP5	O75197-1.2	T945F	Neutral	0.335
LRP5	O75197-1.2	T945G	Pathogenic	0.611
LRP5	O75197-1.2	T945H	Pathogenic	0.646
LRP5	O75197-1.2	T945I	Neutral	0.143
LRP5	O75197-1.2	T945K	Neutral	0.176
LRP5	O75197-1.2	T945L	Neutral	0.154
LRP5	O75197-1.2	T945M	Neutral	0.217
LRP5	O75197-1.2	T945N	Neutral	0.096
LRP5	O75197-1.2	T945P	Neutral	0.315
LRP5	O75197-1.2	T945Q	Neutral	0.306
LRP5	O75197-1.2	T945R	Neutral	0.171
LRP5	O75197-1.2	T945S	Neutral	0.053
LRP5	O75197-1.2	T945V	Neutral	0.087
LRP5	O75197-1.2	T945W	Neutral	0.242
LRP5	O75197-1.2	T945Y	Pathogenic	0.512
LRP5	O75197-1.2	T946A	Neutral	0.259
LRP5	O75197-1.2	T946C	Neutral	0.375
LRP5	O75197-1.2	T946D	Neutral	0.316
LRP5	O75197-1.2	T946E	Neutral	0.337
LRP5	O75197-1.2	T946F	Neutral	0.456
LRP5	O75197-1.2	T946G	Pathogenic	0.723
LRP5	O75197-1.2	T946H	Pathogenic	0.752
LRP5	O75197-1.2	T946I	Neutral	0.217
LRP5	O75197-1.2	T946K	Neutral	0.262
LRP5	O75197-1.2	T946L	Neutral	0.233
LRP5	O75197-1.2	T946M	Neutral	0.316
LRP5	O75197-1.2	T946N	Neutral	0.15
LRP5	O75197-1.2	T946P	Neutral	0.433
LRP5	O75197-1.2	T946Q	Neutral	0.423
LRP5	O75197-1.2	T946R	Neutral	0.256
LRP5	O75197-1.2	T946S	Neutral	0.085
LRP5	O75197-1.2	T946V	Neutral	0.137
LRP5	O75197-1.2	T946W	Neutral	0.346
LRP5	O75197-1.2	T946Y	Pathogenic	0.635
LRP5	O75197-1.2	F947A	Pathogenic	0.997
LRP5	O75197-1.2	F947C	Pathogenic	0.999
LRP5	O75197-1.2	F947D	Pathogenic	0.998
LRP5	O75197-1.2	F947E	Pathogenic	0.998
LRP5	O75197-1.2	F947G	Pathogenic	0.999
LRP5	O75197-1.2	F947H	Pathogenic	0.991
LRP5	O75197-1.2	F947I	Pathogenic	0.994
LRP5	O75197-1.2	F947K	Pathogenic	0.998
LRP5	O75197-1.2	F947L	Pathogenic	0.994
LRP5	O75197-1.2	F947M	Pathogenic	0.99
LRP5	O75197-1.2	F947N	Pathogenic	0.998
LRP5	O75197-1.2	F947P	Pathogenic	1.0
LRP5	O75197-1.2	F947Q	Pathogenic	0.999
LRP5	O75197-1.2	F947R	Pathogenic	0.997
LRP5	O75197-1.2	F947S	Pathogenic	0.996
LRP5	O75197-1.2	F947T	Pathogenic	0.997
LRP5	O75197-1.2	F947V	Pathogenic	0.997
LRP5	O75197-1.2	F947W	Pathogenic	0.973
LRP5	O75197-1.2	F947Y	Pathogenic	0.742
LRP5	O75197-1.2	L948A	Pathogenic	0.948
LRP5	O75197-1.2	L948C	Pathogenic	0.972
LRP5	O75197-1.2	L948D	Pathogenic	0.995
LRP5	O75197-1.2	L948E	Pathogenic	0.987
LRP5	O75197-1.2	L948F	Pathogenic	0.954
LRP5	O75197-1.2	L948G	Pathogenic	0.997
LRP5	O75197-1.2	L948H	Pathogenic	0.994
LRP5	O75197-1.2	L948I	Pathogenic	0.694
LRP5	O75197-1.2	L948K	Pathogenic	0.95
LRP5	O75197-1.2	L948M	Pathogenic	0.62
LRP5	O75197-1.2	L948N	Pathogenic	0.988
LRP5	O75197-1.2	L948P	Pathogenic	0.996
LRP5	O75197-1.2	L948Q	Pathogenic	0.974
LRP5	O75197-1.2	L948R	Pathogenic	0.948
LRP5	O75197-1.2	L948S	Pathogenic	0.976
LRP5	O75197-1.2	L948T	Pathogenic	0.948
LRP5	O75197-1.2	L948V	Pathogenic	0.826
LRP5	O75197-1.2	L948W	Pathogenic	0.992
LRP5	O75197-1.2	L948Y	Pathogenic	0.972
LRP5	O75197-1.2	L949A	Pathogenic	0.948
LRP5	O75197-1.2	L949C	Pathogenic	0.971
LRP5	O75197-1.2	L949D	Pathogenic	0.995
LRP5	O75197-1.2	L949E	Pathogenic	0.987
LRP5	O75197-1.2	L949F	Pathogenic	0.954
LRP5	O75197-1.2	L949G	Pathogenic	0.997
LRP5	O75197-1.2	L949H	Pathogenic	0.994
LRP5	O75197-1.2	L949I	Pathogenic	0.69
LRP5	O75197-1.2	L949K	Pathogenic	0.949
LRP5	O75197-1.2	L949M	Pathogenic	0.616
LRP5	O75197-1.2	L949N	Pathogenic	0.987
LRP5	O75197-1.2	L949P	Pathogenic	0.996
LRP5	O75197-1.2	L949Q	Pathogenic	0.974
LRP5	O75197-1.2	L949R	Pathogenic	0.947
LRP5	O75197-1.2	L949S	Pathogenic	0.976
LRP5	O75197-1.2	L949T	Pathogenic	0.947
LRP5	O75197-1.2	L949V	Pathogenic	0.824
LRP5	O75197-1.2	L949W	Pathogenic	0.992
LRP5	O75197-1.2	L949Y	Pathogenic	0.972
LRP5	O75197-1.2	F950A	Pathogenic	0.99
LRP5	O75197-1.2	F950C	Pathogenic	0.995
LRP5	O75197-1.2	F950D	Pathogenic	0.992
LRP5	O75197-1.2	F950E	Pathogenic	0.993
LRP5	O75197-1.2	F950G	Pathogenic	0.996
LRP5	O75197-1.2	F950H	Pathogenic	0.968
LRP5	O75197-1.2	F950I	Pathogenic	0.978
LRP5	O75197-1.2	F950K	Pathogenic	0.991
LRP5	O75197-1.2	F950L	Pathogenic	0.976
LRP5	O75197-1.2	F950M	Pathogenic	0.965
LRP5	O75197-1.2	F950N	Pathogenic	0.993
LRP5	O75197-1.2	F950P	Pathogenic	0.999
LRP5	O75197-1.2	F950Q	Pathogenic	0.995
LRP5	O75197-1.2	F950R	Pathogenic	0.99
LRP5	O75197-1.2	F950S	Pathogenic	0.987
LRP5	O75197-1.2	F950T	Pathogenic	0.99
LRP5	O75197-1.2	F950V	Pathogenic	0.988
LRP5	O75197-1.2	F950W	Pathogenic	0.905
LRP5	O75197-1.2	F950Y	Neutral	0.433
LRP5	O75197-1.2	S951A	Pathogenic	0.937
LRP5	O75197-1.2	S951C	Pathogenic	0.987
LRP5	O75197-1.2	S951D	Pathogenic	0.969
LRP5	O75197-1.2	S951E	Pathogenic	0.972
LRP5	O75197-1.2	S951F	Pathogenic	0.99
LRP5	O75197-1.2	S951G	Pathogenic	0.983
LRP5	O75197-1.2	S951H	Pathogenic	0.993
LRP5	O75197-1.2	S951I	Pathogenic	0.99
LRP5	O75197-1.2	S951K	Pathogenic	0.96
LRP5	O75197-1.2	S951L	Pathogenic	0.991
LRP5	O75197-1.2	S951M	Pathogenic	0.983
LRP5	O75197-1.2	S951N	Pathogenic	0.923
LRP5	O75197-1.2	S951P	Pathogenic	0.989
LRP5	O75197-1.2	S951Q	Pathogenic	0.98
LRP5	O75197-1.2	S951R	Pathogenic	0.986
LRP5	O75197-1.2	S951T	Pathogenic	0.938
LRP5	O75197-1.2	S951V	Pathogenic	0.994
LRP5	O75197-1.2	S951W	Pathogenic	0.995
LRP5	O75197-1.2	S951Y	Pathogenic	0.995
LRP5	O75197-1.2	Q952A	Pathogenic	0.989
LRP5	O75197-1.2	Q952C	Pathogenic	0.998
LRP5	O75197-1.2	Q952D	Pathogenic	0.969
LRP5	O75197-1.2	Q952E	Pathogenic	0.797
LRP5	O75197-1.2	Q952F	Pathogenic	0.996
LRP5	O75197-1.2	Q952G	Pathogenic	0.997
LRP5	O75197-1.2	Q952H	Pathogenic	0.975
LRP5	O75197-1.2	Q952I	Pathogenic	0.996
LRP5	O75197-1.2	Q952K	Pathogenic	0.895
LRP5	O75197-1.2	Q952L	Pathogenic	0.989
LRP5	O75197-1.2	Q952M	Pathogenic	0.935
LRP5	O75197-1.2	Q952N	Pathogenic	0.973
LRP5	O75197-1.2	Q952P	Pathogenic	0.985
LRP5	O75197-1.2	Q952R	Pathogenic	0.891
LRP5	O75197-1.2	Q952S	Pathogenic	0.977
LRP5	O75197-1.2	Q952T	Pathogenic	0.99
LRP5	O75197-1.2	Q952V	Pathogenic	0.993
LRP5	O75197-1.2	Q952W	Pathogenic	0.98
LRP5	O75197-1.2	Q952Y	Pathogenic	0.982
LRP5	O75197-1.2	K953A	Pathogenic	0.97
LRP5	O75197-1.2	K953C	Pathogenic	0.994
LRP5	O75197-1.2	K953D	Pathogenic	0.989
LRP5	O75197-1.2	K953E	Pathogenic	0.895
LRP5	O75197-1.2	K953F	Pathogenic	0.989
LRP5	O75197-1.2	K953G	Pathogenic	0.992
LRP5	O75197-1.2	K953H	Pathogenic	0.976
LRP5	O75197-1.2	K953I	Pathogenic	0.988
LRP5	O75197-1.2	K953L	Pathogenic	0.968
LRP5	O75197-1.2	K953M	Pathogenic	0.939
LRP5	O75197-1.2	K953N	Pathogenic	0.961
LRP5	O75197-1.2	K953P	Pathogenic	0.958
LRP5	O75197-1.2	K953Q	Pathogenic	0.856
LRP5	O75197-1.2	K953R	Pathogenic	0.795
LRP5	O75197-1.2	K953S	Pathogenic	0.935
LRP5	O75197-1.2	K953T	Pathogenic	0.972
LRP5	O75197-1.2	K953V	Pathogenic	0.979
LRP5	O75197-1.2	K953W	Pathogenic	0.982
LRP5	O75197-1.2	K953Y	Pathogenic	0.984
LRP5	O75197-1.2	S954A	Neutral	0.006
LRP5	O75197-1.2	S954C	Neutral	0.031
LRP5	O75197-1.2	S954D	Neutral	0.013
LRP5	O75197-1.2	S954E	Neutral	0.014
LRP5	O75197-1.2	S954F	Neutral	0.041
LRP5	O75197-1.2	S954G	Neutral	0.024
LRP5	O75197-1.2	S954H	Neutral	0.06
LRP5	O75197-1.2	S954I	Neutral	0.042
LRP5	O75197-1.2	S954K	Neutral	0.01
LRP5	O75197-1.2	S954L	Neutral	0.045
LRP5	O75197-1.2	S954M	Neutral	0.023
LRP5	O75197-1.2	S954N	Neutral	0.005
LRP5	O75197-1.2	S954P	Neutral	0.038
LRP5	O75197-1.2	S954Q	Neutral	0.021
LRP5	O75197-1.2	S954R	Neutral	0.029
LRP5	O75197-1.2	S954T	Neutral	0.006
LRP5	O75197-1.2	S954V	Neutral	0.07
LRP5	O75197-1.2	S954W	Neutral	0.077
LRP5	O75197-1.2	S954Y	Neutral	0.083
LRP5	O75197-1.2	A955C	Pathogenic	0.54
LRP5	O75197-1.2	A955D	Pathogenic	0.883
LRP5	O75197-1.2	A955E	Pathogenic	0.73
LRP5	O75197-1.2	A955F	Pathogenic	0.83
LRP5	O75197-1.2	A955G	Pathogenic	0.62
LRP5	O75197-1.2	A955H	Pathogenic	0.942
LRP5	O75197-1.2	A955I	Pathogenic	0.618
LRP5	O75197-1.2	A955K	Pathogenic	0.654
LRP5	O75197-1.2	A955L	Pathogenic	0.639
LRP5	O75197-1.2	A955M	Pathogenic	0.729
LRP5	O75197-1.2	A955N	Pathogenic	0.897
LRP5	O75197-1.2	A955P	Pathogenic	0.818
LRP5	O75197-1.2	A955Q	Pathogenic	0.796
LRP5	O75197-1.2	A955R	Pathogenic	0.647
LRP5	O75197-1.2	A955S	Neutral	0.346
LRP5	O75197-1.2	A955T	Pathogenic	0.67
LRP5	O75197-1.2	A955V	Neutral	0.48
LRP5	O75197-1.2	A955W	Pathogenic	0.904
LRP5	O75197-1.2	A955Y	Pathogenic	0.91
LRP5	O75197-1.2	I956A	Pathogenic	0.976
LRP5	O75197-1.2	I956C	Pathogenic	0.987
LRP5	O75197-1.2	I956D	Pathogenic	0.993
LRP5	O75197-1.2	I956E	Pathogenic	0.994
LRP5	O75197-1.2	I956F	Pathogenic	0.982
LRP5	O75197-1.2	I956G	Pathogenic	0.999
LRP5	O75197-1.2	I956H	Pathogenic	0.997
LRP5	O75197-1.2	I956K	Pathogenic	0.992
LRP5	O75197-1.2	I956L	Pathogenic	0.849
LRP5	O75197-1.2	I956M	Pathogenic	0.918
LRP5	O75197-1.2	I956N	Pathogenic	0.994
LRP5	O75197-1.2	I956P	Pathogenic	0.998
LRP5	O75197-1.2	I956Q	Pathogenic	0.996
LRP5	O75197-1.2	I956R	Pathogenic	0.992
LRP5	O75197-1.2	I956S	Pathogenic	0.989
LRP5	O75197-1.2	I956T	Pathogenic	0.976
LRP5	O75197-1.2	I956V	Pathogenic	0.537
LRP5	O75197-1.2	I956W	Pathogenic	0.999
LRP5	O75197-1.2	I956Y	Pathogenic	0.988
LRP5	O75197-1.2	S957A	Neutral	0.068
LRP5	O75197-1.2	S957C	Neutral	0.268
LRP5	O75197-1.2	S957D	Neutral	0.134
LRP5	O75197-1.2	S957E	Neutral	0.144
LRP5	O75197-1.2	S957F	Neutral	0.334
LRP5	O75197-1.2	S957G	Neutral	0.222
LRP5	O75197-1.2	S957H	Neutral	0.427
LRP5	O75197-1.2	S957I	Neutral	0.335
LRP5	O75197-1.2	S957K	Neutral	0.106
LRP5	O75197-1.2	S957L	Neutral	0.356
LRP5	O75197-1.2	S957M	Neutral	0.216
LRP5	O75197-1.2	S957N	Neutral	0.055
LRP5	O75197-1.2	S957P	Neutral	0.316
LRP5	O75197-1.2	S957Q	Neutral	0.196
LRP5	O75197-1.2	S957R	Neutral	0.258
LRP5	O75197-1.2	S957T	Neutral	0.07
LRP5	O75197-1.2	S957V	Neutral	0.467
LRP5	O75197-1.2	S957W	Neutral	0.491
LRP5	O75197-1.2	S957Y	Pathogenic	0.51
LRP5	O75197-1.2	R958A	Pathogenic	0.991
LRP5	O75197-1.2	R958C	Pathogenic	0.998
LRP5	O75197-1.2	R958D	Pathogenic	0.999
LRP5	O75197-1.2	R958E	Pathogenic	0.989
LRP5	O75197-1.2	R958F	Pathogenic	0.997
LRP5	O75197-1.2	R958G	Pathogenic	0.998
LRP5	O75197-1.2	R958H	Pathogenic	0.979
LRP5	O75197-1.2	R958I	Pathogenic	0.997
LRP5	O75197-1.2	R958K	Pathogenic	0.934
LRP5	O75197-1.2	R958L	Pathogenic	0.991
LRP5	O75197-1.2	R958M	Pathogenic	0.982
LRP5	O75197-1.2	R958N	Pathogenic	0.989
LRP5	O75197-1.2	R958P	Pathogenic	0.996
LRP5	O75197-1.2	R958Q	Pathogenic	0.954
LRP5	O75197-1.2	R958S	Pathogenic	0.994
LRP5	O75197-1.2	R958T	Pathogenic	0.992
LRP5	O75197-1.2	R958V	Pathogenic	0.998
LRP5	O75197-1.2	R958W	Pathogenic	0.995
LRP5	O75197-1.2	R958Y	Pathogenic	0.995
LRP5	O75197-1.2	M959A	Pathogenic	0.972
LRP5	O75197-1.2	M959C	Pathogenic	0.985
LRP5	O75197-1.2	M959D	Pathogenic	0.992
LRP5	O75197-1.2	M959E	Pathogenic	0.98
LRP5	O75197-1.2	M959F	Pathogenic	0.944
LRP5	O75197-1.2	M959G	Pathogenic	0.996
LRP5	O75197-1.2	M959H	Pathogenic	0.99
LRP5	O75197-1.2	M959I	Pathogenic	0.848
LRP5	O75197-1.2	M959K	Pathogenic	0.921
LRP5	O75197-1.2	M959L	Pathogenic	0.668
LRP5	O75197-1.2	M959N	Pathogenic	0.98
LRP5	O75197-1.2	M959P	Pathogenic	0.994
LRP5	O75197-1.2	M959Q	Pathogenic	0.884
LRP5	O75197-1.2	M959R	Pathogenic	0.918
LRP5	O75197-1.2	M959S	Pathogenic	0.962
LRP5	O75197-1.2	M959T	Pathogenic	0.972
LRP5	O75197-1.2	M959V	Pathogenic	0.899
LRP5	O75197-1.2	M959W	Pathogenic	0.97
LRP5	O75197-1.2	M959Y	Pathogenic	0.985
LRP5	O75197-1.2	I960A	Neutral	0.282
LRP5	O75197-1.2	I960C	Neutral	0.425
LRP5	O75197-1.2	I960D	Pathogenic	0.59
LRP5	O75197-1.2	I960E	Pathogenic	0.625
LRP5	O75197-1.2	I960F	Neutral	0.343
LRP5	O75197-1.2	I960G	Pathogenic	0.891
LRP5	O75197-1.2	I960H	Pathogenic	0.771
LRP5	O75197-1.2	I960K	Pathogenic	0.551
LRP5	O75197-1.2	I960L	Neutral	0.05
LRP5	O75197-1.2	I960M	Neutral	0.096
LRP5	O75197-1.2	I960N	Pathogenic	0.628
LRP5	O75197-1.2	I960P	Pathogenic	0.845
LRP5	O75197-1.2	I960Q	Pathogenic	0.71
LRP5	O75197-1.2	I960R	Pathogenic	0.543
LRP5	O75197-1.2	I960S	Neutral	0.47
LRP5	O75197-1.2	I960T	Neutral	0.281
LRP5	O75197-1.2	I960V	Neutral	0.011
LRP5	O75197-1.2	I960W	Pathogenic	0.905
LRP5	O75197-1.2	I960Y	Neutral	0.429
LRP5	O75197-1.2	P961A	Neutral	0.289
LRP5	O75197-1.2	P961C	Pathogenic	0.815
LRP5	O75197-1.2	P961D	Neutral	0.138
LRP5	O75197-1.2	P961E	Neutral	0.149
LRP5	O75197-1.2	P961F	Pathogenic	0.859
LRP5	O75197-1.2	P961G	Neutral	0.476
LRP5	O75197-1.2	P961H	Pathogenic	0.511
LRP5	O75197-1.2	P961I	Pathogenic	0.669
LRP5	O75197-1.2	P961K	Neutral	0.109
LRP5	O75197-1.2	P961L	Pathogenic	0.689
LRP5	O75197-1.2	P961M	Pathogenic	0.525
LRP5	O75197-1.2	P961N	Neutral	0.36
LRP5	O75197-1.2	P961Q	Neutral	0.202
LRP5	O75197-1.2	P961R	Neutral	0.265
LRP5	O75197-1.2	P961S	Neutral	0.231
LRP5	O75197-1.2	P961T	Neutral	0.286
LRP5	O75197-1.2	P961V	Pathogenic	0.536
LRP5	O75197-1.2	P961W	Pathogenic	0.794
LRP5	O75197-1.2	P961Y	Pathogenic	0.807
LRP5	O75197-1.2	D962A	Pathogenic	0.956
LRP5	O75197-1.2	D962C	Pathogenic	0.974
LRP5	O75197-1.2	D962E	Neutral	0.376
LRP5	O75197-1.2	D962F	Pathogenic	0.945
LRP5	O75197-1.2	D962G	Pathogenic	0.902
LRP5	O75197-1.2	D962H	Pathogenic	0.894
LRP5	O75197-1.2	D962I	Pathogenic	0.945
LRP5	O75197-1.2	D962K	Pathogenic	0.938
LRP5	O75197-1.2	D962L	Pathogenic	0.983
LRP5	O75197-1.2	D962M	Pathogenic	0.966
LRP5	O75197-1.2	D962N	Pathogenic	0.644
LRP5	O75197-1.2	D962P	Pathogenic	0.838
LRP5	O75197-1.2	D962Q	Pathogenic	0.792
LRP5	O75197-1.2	D962R	Pathogenic	0.978
LRP5	O75197-1.2	D962S	Pathogenic	0.765
LRP5	O75197-1.2	D962T	Pathogenic	0.887
LRP5	O75197-1.2	D962V	Pathogenic	0.968
LRP5	O75197-1.2	D962W	Pathogenic	0.971
LRP5	O75197-1.2	D962Y	Pathogenic	0.973
LRP5	O75197-1.2	D963A	Neutral	0.246
LRP5	O75197-1.2	D963C	Neutral	0.359
LRP5	O75197-1.2	D963E	Neutral	0.009
LRP5	O75197-1.2	D963F	Neutral	0.204
LRP5	O75197-1.2	D963G	Neutral	0.121
LRP5	O75197-1.2	D963H	Neutral	0.111
LRP5	O75197-1.2	D963I	Neutral	0.205
LRP5	O75197-1.2	D963K	Neutral	0.183
LRP5	O75197-1.2	D963L	Neutral	0.462
LRP5	O75197-1.2	D963M	Neutral	0.3
LRP5	O75197-1.2	D963N	Neutral	0.026
LRP5	O75197-1.2	D963P	Neutral	0.072
LRP5	O75197-1.2	D963Q	Neutral	0.054
LRP5	O75197-1.2	D963R	Neutral	0.397
LRP5	O75197-1.2	D963S	Neutral	0.046
LRP5	O75197-1.2	D963T	Neutral	0.104
LRP5	O75197-1.2	D963V	Neutral	0.309
LRP5	O75197-1.2	D963W	Neutral	0.33
LRP5	O75197-1.2	D963Y	Neutral	0.347
LRP5	O75197-1.2	Q964A	Pathogenic	0.865
LRP5	O75197-1.2	Q964C	Pathogenic	0.971
LRP5	O75197-1.2	Q964D	Pathogenic	0.682
LRP5	O75197-1.2	Q964E	Neutral	0.212
LRP5	O75197-1.2	Q964F	Pathogenic	0.943
LRP5	O75197-1.2	Q964G	Pathogenic	0.961
LRP5	O75197-1.2	Q964H	Pathogenic	0.725
LRP5	O75197-1.2	Q964I	Pathogenic	0.943
LRP5	O75197-1.2	Q964K	Neutral	0.368
LRP5	O75197-1.2	Q964L	Pathogenic	0.856
LRP5	O75197-1.2	Q964M	Neutral	0.495
LRP5	O75197-1.2	Q964N	Pathogenic	0.716
LRP5	O75197-1.2	Q964P	Pathogenic	0.822
LRP5	O75197-1.2	Q964R	Neutral	0.36
LRP5	O75197-1.2	Q964S	Pathogenic	0.743
LRP5	O75197-1.2	Q964T	Pathogenic	0.875
LRP5	O75197-1.2	Q964V	Pathogenic	0.902
LRP5	O75197-1.2	Q964W	Pathogenic	0.774
LRP5	O75197-1.2	Q964Y	Pathogenic	0.787
LRP5	O75197-1.2	H965A	Neutral	0.334
LRP5	O75197-1.2	H965C	Neutral	0.462
LRP5	O75197-1.2	H965D	Neutral	0.082
LRP5	O75197-1.2	H965E	Neutral	0.033
LRP5	O75197-1.2	H965F	Neutral	0.044
LRP5	O75197-1.2	H965G	Neutral	0.336
LRP5	O75197-1.2	H965I	Neutral	0.301
LRP5	O75197-1.2	H965K	Neutral	0.069
LRP5	O75197-1.2	H965L	Neutral	0.32
LRP5	O75197-1.2	H965M	Neutral	0.191
LRP5	O75197-1.2	H965N	Neutral	0.011
LRP5	O75197-1.2	H965P	Neutral	0.265
LRP5	O75197-1.2	H965Q	Neutral	0.047
LRP5	O75197-1.2	H965R	Neutral	0.023
LRP5	O75197-1.2	H965S	Neutral	0.143
LRP5	O75197-1.2	H965T	Neutral	0.353
LRP5	O75197-1.2	H965V	Neutral	0.418
LRP5	O75197-1.2	H965W	Neutral	0.082
LRP5	O75197-1.2	H965Y	Neutral	0.003
LRP5	O75197-1.2	S966A	Pathogenic	0.707
LRP5	O75197-1.2	S966C	Pathogenic	0.924
LRP5	O75197-1.2	S966D	Pathogenic	0.836
LRP5	O75197-1.2	S966E	Pathogenic	0.848
LRP5	O75197-1.2	S966F	Pathogenic	0.943
LRP5	O75197-1.2	S966G	Pathogenic	0.904
LRP5	O75197-1.2	S966H	Pathogenic	0.961
LRP5	O75197-1.2	S966I	Pathogenic	0.943
LRP5	O75197-1.2	S966K	Pathogenic	0.796
LRP5	O75197-1.2	S966L	Pathogenic	0.948
LRP5	O75197-1.2	S966M	Pathogenic	0.901
LRP5	O75197-1.2	S966N	Pathogenic	0.659
LRP5	O75197-1.2	S966P	Pathogenic	0.938
LRP5	O75197-1.2	S966Q	Pathogenic	0.889
LRP5	O75197-1.2	S966R	Pathogenic	0.92
LRP5	O75197-1.2	S966T	Pathogenic	0.712
LRP5	O75197-1.2	S966V	Pathogenic	0.967
LRP5	O75197-1.2	S966W	Pathogenic	0.97
LRP5	O75197-1.2	S966Y	Pathogenic	0.972
LRP5	O75197-1.2	P967A	Pathogenic	0.99
LRP5	O75197-1.2	P967C	Pathogenic	0.999
LRP5	O75197-1.2	P967D	Pathogenic	0.974
LRP5	O75197-1.2	P967E	Pathogenic	0.976
LRP5	O75197-1.2	P967F	Pathogenic	0.999
LRP5	O75197-1.2	P967G	Pathogenic	0.995
LRP5	O75197-1.2	P967H	Pathogenic	0.996
LRP5	O75197-1.2	P967I	Pathogenic	0.998
LRP5	O75197-1.2	P967K	Pathogenic	0.966
LRP5	O75197-1.2	P967L	Pathogenic	0.998
LRP5	O75197-1.2	P967M	Pathogenic	0.996
LRP5	O75197-1.2	P967N	Pathogenic	0.992
LRP5	O75197-1.2	P967Q	Pathogenic	0.983
LRP5	O75197-1.2	P967R	Pathogenic	0.988
LRP5	O75197-1.2	P967S	Pathogenic	0.986
LRP5	O75197-1.2	P967T	Pathogenic	0.989
LRP5	O75197-1.2	P967V	Pathogenic	0.996
LRP5	O75197-1.2	P967W	Pathogenic	0.999
LRP5	O75197-1.2	P967Y	Pathogenic	0.999
LRP5	O75197-1.2	D968A	Pathogenic	0.993
LRP5	O75197-1.2	D968C	Pathogenic	0.996
LRP5	O75197-1.2	D968E	Pathogenic	0.805
LRP5	O75197-1.2	D968F	Pathogenic	0.992
LRP5	O75197-1.2	D968G	Pathogenic	0.984
LRP5	O75197-1.2	D968H	Pathogenic	0.983
LRP5	O75197-1.2	D968I	Pathogenic	0.992
LRP5	O75197-1.2	D968K	Pathogenic	0.99
LRP5	O75197-1.2	D968L	Pathogenic	0.997
LRP5	O75197-1.2	D968M	Pathogenic	0.995
LRP5	O75197-1.2	D968N	Pathogenic	0.925
LRP5	O75197-1.2	D968P	Pathogenic	0.973
LRP5	O75197-1.2	D968Q	Pathogenic	0.963
LRP5	O75197-1.2	D968R	Pathogenic	0.997
LRP5	O75197-1.2	D968S	Pathogenic	0.957
LRP5	O75197-1.2	D968T	Pathogenic	0.982
LRP5	O75197-1.2	D968V	Pathogenic	0.995
LRP5	O75197-1.2	D968W	Pathogenic	0.996
LRP5	O75197-1.2	D968Y	Pathogenic	0.996
LRP5	O75197-1.2	L969A	Neutral	0.139
LRP5	O75197-1.2	L969C	Neutral	0.234
LRP5	O75197-1.2	L969D	Pathogenic	0.643
LRP5	O75197-1.2	L969E	Neutral	0.407
LRP5	O75197-1.2	L969F	Neutral	0.155
LRP5	O75197-1.2	L969G	Pathogenic	0.77
LRP5	O75197-1.2	L969H	Pathogenic	0.581
LRP5	O75197-1.2	L969I	Neutral	0.02
LRP5	O75197-1.2	L969K	Neutral	0.142
LRP5	O75197-1.2	L969M	Neutral	0.014
LRP5	O75197-1.2	L969N	Neutral	0.41
LRP5	O75197-1.2	L969P	Pathogenic	0.691
LRP5	O75197-1.2	L969Q	Neutral	0.249
LRP5	O75197-1.2	L969R	Neutral	0.138
LRP5	O75197-1.2	L969S	Neutral	0.267
LRP5	O75197-1.2	L969T	Neutral	0.139
LRP5	O75197-1.2	L969V	Neutral	0.04
LRP5	O75197-1.2	L969W	Pathogenic	0.518
LRP5	O75197-1.2	L969Y	Neutral	0.236
LRP5	O75197-1.2	I970A	Pathogenic	0.798
LRP5	O75197-1.2	I970C	Pathogenic	0.881
LRP5	O75197-1.2	I970D	Pathogenic	0.935
LRP5	O75197-1.2	I970E	Pathogenic	0.944
LRP5	O75197-1.2	I970F	Pathogenic	0.84
LRP5	O75197-1.2	I970G	Pathogenic	0.988
LRP5	O75197-1.2	I970H	Pathogenic	0.971
LRP5	O75197-1.2	I970K	Pathogenic	0.925
LRP5	O75197-1.2	I970L	Neutral	0.348
LRP5	O75197-1.2	I970M	Pathogenic	0.516
LRP5	O75197-1.2	I970N	Pathogenic	0.944
LRP5	O75197-1.2	I970P	Pathogenic	0.982
LRP5	O75197-1.2	I970Q	Pathogenic	0.961
LRP5	O75197-1.2	I970R	Pathogenic	0.922
LRP5	O75197-1.2	I970S	Pathogenic	0.899
LRP5	O75197-1.2	I970T	Pathogenic	0.797
LRP5	O75197-1.2	I970V	Neutral	0.099
LRP5	O75197-1.2	I970W	Pathogenic	0.99
LRP5	O75197-1.2	I970Y	Pathogenic	0.883
LRP5	O75197-1.2	L971A	Pathogenic	0.987
LRP5	O75197-1.2	L971C	Pathogenic	0.993
LRP5	O75197-1.2	L971D	Pathogenic	0.999
LRP5	O75197-1.2	L971E	Pathogenic	0.997
LRP5	O75197-1.2	L971F	Pathogenic	0.989
LRP5	O75197-1.2	L971G	Pathogenic	0.999
LRP5	O75197-1.2	L971H	Pathogenic	0.998
LRP5	O75197-1.2	L971I	Pathogenic	0.904
LRP5	O75197-1.2	L971K	Pathogenic	0.987
LRP5	O75197-1.2	L971M	Pathogenic	0.872
LRP5	O75197-1.2	L971N	Pathogenic	0.997
LRP5	O75197-1.2	L971P	Pathogenic	0.999
LRP5	O75197-1.2	L971Q	Pathogenic	0.994
LRP5	O75197-1.2	L971R	Pathogenic	0.987
LRP5	O75197-1.2	L971S	Pathogenic	0.994
LRP5	O75197-1.2	L971T	Pathogenic	0.987
LRP5	O75197-1.2	L971V	Pathogenic	0.952
LRP5	O75197-1.2	L971W	Pathogenic	0.998
LRP5	O75197-1.2	L971Y	Pathogenic	0.993
LRP5	O75197-1.2	P972A	Pathogenic	0.989
LRP5	O75197-1.2	P972C	Pathogenic	0.999
LRP5	O75197-1.2	P972D	Pathogenic	0.972
LRP5	O75197-1.2	P972E	Pathogenic	0.975
LRP5	O75197-1.2	P972F	Pathogenic	0.999
LRP5	O75197-1.2	P972G	Pathogenic	0.995
LRP5	O75197-1.2	P972H	Pathogenic	0.996
LRP5	O75197-1.2	P972I	Pathogenic	0.998
LRP5	O75197-1.2	P972K	Pathogenic	0.964
LRP5	O75197-1.2	P972L	Pathogenic	0.998
LRP5	O75197-1.2	P972M	Pathogenic	0.996
LRP5	O75197-1.2	P972N	Pathogenic	0.992
LRP5	O75197-1.2	P972Q	Pathogenic	0.982
LRP5	O75197-1.2	P972R	Pathogenic	0.988
LRP5	O75197-1.2	P972S	Pathogenic	0.985
LRP5	O75197-1.2	P972T	Pathogenic	0.989
LRP5	O75197-1.2	P972V	Pathogenic	0.996
LRP5	O75197-1.2	P972W	Pathogenic	0.999
LRP5	O75197-1.2	P972Y	Pathogenic	0.999
LRP5	O75197-1.2	L973A	Neutral	0.187
LRP5	O75197-1.2	L973C	Neutral	0.302
LRP5	O75197-1.2	L973D	Pathogenic	0.719
LRP5	O75197-1.2	L973E	Neutral	0.494
LRP5	O75197-1.2	L973F	Neutral	0.207
LRP5	O75197-1.2	L973G	Pathogenic	0.826
LRP5	O75197-1.2	L973H	Pathogenic	0.663
LRP5	O75197-1.2	L973I	Neutral	0.028
LRP5	O75197-1.2	L973K	Neutral	0.191
LRP5	O75197-1.2	L973M	Neutral	0.02
LRP5	O75197-1.2	L973N	Neutral	0.497
LRP5	O75197-1.2	L973P	Pathogenic	0.761
LRP5	O75197-1.2	L973Q	Neutral	0.319
LRP5	O75197-1.2	L973R	Neutral	0.185
LRP5	O75197-1.2	L973S	Neutral	0.341
LRP5	O75197-1.2	L973T	Neutral	0.186
LRP5	O75197-1.2	L973V	Neutral	0.056
LRP5	O75197-1.2	L973W	Pathogenic	0.604
LRP5	O75197-1.2	L973Y	Neutral	0.305
LRP5	O75197-1.2	H974A	Pathogenic	0.996
LRP5	O75197-1.2	H974C	Pathogenic	0.997
LRP5	O75197-1.2	H974D	Pathogenic	0.976
LRP5	O75197-1.2	H974E	Pathogenic	0.94
LRP5	O75197-1.2	H974F	Pathogenic	0.955
LRP5	O75197-1.2	H974G	Pathogenic	0.996
LRP5	O75197-1.2	H974I	Pathogenic	0.995
LRP5	O75197-1.2	H974K	Pathogenic	0.972
LRP5	O75197-1.2	H974L	Pathogenic	0.995
LRP5	O75197-1.2	H974M	Pathogenic	0.991
LRP5	O75197-1.2	H974N	Pathogenic	0.839
LRP5	O75197-1.2	H974P	Pathogenic	0.994
LRP5	O75197-1.2	H974Q	Pathogenic	0.958
LRP5	O75197-1.2	H974R	Pathogenic	0.916
LRP5	O75197-1.2	H974S	Pathogenic	0.987
LRP5	O75197-1.2	H974T	Pathogenic	0.996
LRP5	O75197-1.2	H974V	Pathogenic	0.997
LRP5	O75197-1.2	H974W	Pathogenic	0.976
LRP5	O75197-1.2	H974Y	Pathogenic	0.61
LRP5	O75197-1.2	G975A	Neutral	0.126
LRP5	O75197-1.2	G975C	Pathogenic	0.683
LRP5	O75197-1.2	G975D	Neutral	0.219
LRP5	O75197-1.2	G975E	Neutral	0.482
LRP5	O75197-1.2	G975F	Neutral	0.492
LRP5	O75197-1.2	G975H	Pathogenic	0.59
LRP5	O75197-1.2	G975I	Pathogenic	0.748
LRP5	O75197-1.2	G975K	Neutral	0.395
LRP5	O75197-1.2	G975L	Pathogenic	0.765
LRP5	O75197-1.2	G975M	Pathogenic	0.619
LRP5	O75197-1.2	G975N	Neutral	0.096
LRP5	O75197-1.2	G975P	Neutral	0.472
LRP5	O75197-1.2	G975Q	Pathogenic	0.573
LRP5	O75197-1.2	G975R	Neutral	0.386
LRP5	O75197-1.2	G975S	Neutral	0.154
LRP5	O75197-1.2	G975T	Pathogenic	0.573
LRP5	O75197-1.2	G975V	Pathogenic	0.629
LRP5	O75197-1.2	G975W	Neutral	0.168
LRP5	O75197-1.2	G975Y	Pathogenic	0.668
LRP5	O75197-1.2	L976A	Pathogenic	0.946
LRP5	O75197-1.2	L976C	Pathogenic	0.971
LRP5	O75197-1.2	L976D	Pathogenic	0.995
LRP5	O75197-1.2	L976E	Pathogenic	0.987
LRP5	O75197-1.2	L976F	Pathogenic	0.952
LRP5	O75197-1.2	L976G	Pathogenic	0.997
LRP5	O75197-1.2	L976H	Pathogenic	0.993
LRP5	O75197-1.2	L976I	Pathogenic	0.684
LRP5	O75197-1.2	L976K	Pathogenic	0.947
LRP5	O75197-1.2	L976M	Pathogenic	0.609
LRP5	O75197-1.2	L976N	Pathogenic	0.987
LRP5	O75197-1.2	L976P	Pathogenic	0.996
LRP5	O75197-1.2	L976Q	Pathogenic	0.973
LRP5	O75197-1.2	L976R	Pathogenic	0.946
LRP5	O75197-1.2	L976S	Pathogenic	0.975
LRP5	O75197-1.2	L976T	Pathogenic	0.946
LRP5	O75197-1.2	L976V	Pathogenic	0.819
LRP5	O75197-1.2	L976W	Pathogenic	0.991
LRP5	O75197-1.2	L976Y	Pathogenic	0.971
LRP5	O75197-1.2	R977A	Pathogenic	0.907
LRP5	O75197-1.2	R977C	Pathogenic	0.981
LRP5	O75197-1.2	R977D	Pathogenic	0.988
LRP5	O75197-1.2	R977E	Pathogenic	0.889
LRP5	O75197-1.2	R977F	Pathogenic	0.964
LRP5	O75197-1.2	R977G	Pathogenic	0.974
LRP5	O75197-1.2	R977H	Pathogenic	0.803
LRP5	O75197-1.2	R977I	Pathogenic	0.963
LRP5	O75197-1.2	R977K	Pathogenic	0.552
LRP5	O75197-1.2	R977L	Pathogenic	0.903
LRP5	O75197-1.2	R977M	Pathogenic	0.824
LRP5	O75197-1.2	R977N	Pathogenic	0.883
LRP5	O75197-1.2	R977P	Pathogenic	0.955
LRP5	O75197-1.2	R977Q	Pathogenic	0.646
LRP5	O75197-1.2	R977S	Pathogenic	0.931
LRP5	O75197-1.2	R977T	Pathogenic	0.914
LRP5	O75197-1.2	R977V	Pathogenic	0.977
LRP5	O75197-1.2	R977W	Pathogenic	0.946
LRP5	O75197-1.2	R977Y	Pathogenic	0.949
LRP5	O75197-1.2	N978A	Pathogenic	0.994
LRP5	O75197-1.2	N978C	Pathogenic	0.996
LRP5	O75197-1.2	N978D	Pathogenic	0.918
LRP5	O75197-1.2	N978E	Pathogenic	0.974
LRP5	O75197-1.2	N978F	Pathogenic	0.992
LRP5	O75197-1.2	N978G	Pathogenic	0.956
LRP5	O75197-1.2	N978H	Pathogenic	0.869
LRP5	O75197-1.2	N978I	Pathogenic	0.992
LRP5	O75197-1.2	N978K	Pathogenic	0.964
LRP5	O75197-1.2	N978L	Pathogenic	0.993
LRP5	O75197-1.2	N978M	Pathogenic	0.986
LRP5	O75197-1.2	N978P	Pathogenic	0.991
LRP5	O75197-1.2	N978Q	Pathogenic	0.965
LRP5	O75197-1.2	N978R	Pathogenic	0.963
LRP5	O75197-1.2	N978S	Pathogenic	0.885
LRP5	O75197-1.2	N978T	Pathogenic	0.949
LRP5	O75197-1.2	N978V	Pathogenic	0.995
LRP5	O75197-1.2	N978W	Pathogenic	0.996
LRP5	O75197-1.2	N978Y	Pathogenic	0.988
LRP5	O75197-1.2	V979A	Pathogenic	0.944
LRP5	O75197-1.2	V979C	Pathogenic	0.99
LRP5	O75197-1.2	V979D	Pathogenic	0.995
LRP5	O75197-1.2	V979E	Pathogenic	0.986
LRP5	O75197-1.2	V979F	Pathogenic	0.986
LRP5	O75197-1.2	V979G	Pathogenic	0.997
LRP5	O75197-1.2	V979H	Pathogenic	0.998
LRP5	O75197-1.2	V979I	Neutral	0.453
LRP5	O75197-1.2	V979K	Pathogenic	0.98
LRP5	O75197-1.2	V979L	Pathogenic	0.894
LRP5	O75197-1.2	V979M	Pathogenic	0.927
LRP5	O75197-1.2	V979N	Pathogenic	0.996
LRP5	O75197-1.2	V979P	Pathogenic	0.996
LRP5	O75197-1.2	V979Q	Pathogenic	0.99
LRP5	O75197-1.2	V979R	Pathogenic	0.993
LRP5	O75197-1.2	V979S	Pathogenic	0.991
LRP5	O75197-1.2	V979T	Pathogenic	0.944
LRP5	O75197-1.2	V979W	Pathogenic	0.998
LRP5	O75197-1.2	V979Y	Pathogenic	0.989
LRP5	O75197-1.2	K980A	Pathogenic	0.803
LRP5	O75197-1.2	K980C	Pathogenic	0.955
LRP5	O75197-1.2	K980D	Pathogenic	0.917
LRP5	O75197-1.2	K980E	Pathogenic	0.523
LRP5	O75197-1.2	K980F	Pathogenic	0.918
LRP5	O75197-1.2	K980G	Pathogenic	0.941
LRP5	O75197-1.2	K980H	Pathogenic	0.838
LRP5	O75197-1.2	K980I	Pathogenic	0.916
LRP5	O75197-1.2	K980L	Pathogenic	0.796
LRP5	O75197-1.2	K980M	Pathogenic	0.662
LRP5	O75197-1.2	K980N	Pathogenic	0.76
LRP5	O75197-1.2	K980P	Pathogenic	0.746
LRP5	O75197-1.2	K980Q	Neutral	0.432
LRP5	O75197-1.2	K980R	Neutral	0.333
LRP5	O75197-1.2	K980S	Pathogenic	0.648
LRP5	O75197-1.2	K980T	Pathogenic	0.817
LRP5	O75197-1.2	K980V	Pathogenic	0.854
LRP5	O75197-1.2	K980W	Pathogenic	0.876
LRP5	O75197-1.2	K980Y	Pathogenic	0.884
LRP5	O75197-1.2	A981C	Pathogenic	0.963
LRP5	O75197-1.2	A981D	Pathogenic	0.994
LRP5	O75197-1.2	A981E	Pathogenic	0.984
LRP5	O75197-1.2	A981F	Pathogenic	0.991
LRP5	O75197-1.2	A981G	Pathogenic	0.973
LRP5	O75197-1.2	A981H	Pathogenic	0.997
LRP5	O75197-1.2	A981I	Pathogenic	0.973
LRP5	O75197-1.2	A981K	Pathogenic	0.977
LRP5	O75197-1.2	A981L	Pathogenic	0.975
LRP5	O75197-1.2	A981M	Pathogenic	0.984
LRP5	O75197-1.2	A981N	Pathogenic	0.995
LRP5	O75197-1.2	A981P	Pathogenic	0.99
LRP5	O75197-1.2	A981Q	Pathogenic	0.989
LRP5	O75197-1.2	A981R	Pathogenic	0.976
LRP5	O75197-1.2	A981S	Pathogenic	0.922
LRP5	O75197-1.2	A981T	Pathogenic	0.978
LRP5	O75197-1.2	A981V	Pathogenic	0.954
LRP5	O75197-1.2	A981W	Pathogenic	0.995
LRP5	O75197-1.2	A981Y	Pathogenic	0.996
LRP5	O75197-1.2	I982A	Pathogenic	0.91
LRP5	O75197-1.2	I982C	Pathogenic	0.95
LRP5	O75197-1.2	I982D	Pathogenic	0.974
LRP5	O75197-1.2	I982E	Pathogenic	0.977
LRP5	O75197-1.2	I982F	Pathogenic	0.931
LRP5	O75197-1.2	I982G	Pathogenic	0.995
LRP5	O75197-1.2	I982H	Pathogenic	0.989
LRP5	O75197-1.2	I982K	Pathogenic	0.969
LRP5	O75197-1.2	I982L	Pathogenic	0.577
LRP5	O75197-1.2	I982M	Pathogenic	0.732
LRP5	O75197-1.2	I982N	Pathogenic	0.977
LRP5	O75197-1.2	I982P	Pathogenic	0.993
LRP5	O75197-1.2	I982Q	Pathogenic	0.984
LRP5	O75197-1.2	I982R	Pathogenic	0.968
LRP5	O75197-1.2	I982S	Pathogenic	0.958
LRP5	O75197-1.2	I982T	Pathogenic	0.909
LRP5	O75197-1.2	I982V	Neutral	0.22
LRP5	O75197-1.2	I982W	Pathogenic	0.996
LRP5	O75197-1.2	I982Y	Pathogenic	0.951
LRP5	O75197-1.2	D983A	Pathogenic	0.744
LRP5	O75197-1.2	D983C	Pathogenic	0.833
LRP5	O75197-1.2	D983E	Neutral	0.074
LRP5	O75197-1.2	D983F	Pathogenic	0.695
LRP5	O75197-1.2	D983G	Pathogenic	0.55
LRP5	O75197-1.2	D983H	Pathogenic	0.527
LRP5	O75197-1.2	D983I	Pathogenic	0.696
LRP5	O75197-1.2	D983K	Pathogenic	0.666
LRP5	O75197-1.2	D983L	Pathogenic	0.884
LRP5	O75197-1.2	D983M	Pathogenic	0.792
LRP5	O75197-1.2	D983N	Neutral	0.194
LRP5	O75197-1.2	D983P	Neutral	0.407
LRP5	O75197-1.2	D983Q	Neutral	0.335
LRP5	O75197-1.2	D983R	Pathogenic	0.854
LRP5	O75197-1.2	D983S	Neutral	0.302
LRP5	O75197-1.2	D983T	Pathogenic	0.509
LRP5	O75197-1.2	D983V	Pathogenic	0.8
LRP5	O75197-1.2	D983W	Pathogenic	0.814
LRP5	O75197-1.2	D983Y	Pathogenic	0.826
LRP5	O75197-1.2	Y984A	Pathogenic	0.996
LRP5	O75197-1.2	Y984C	Pathogenic	0.998
LRP5	O75197-1.2	Y984D	Pathogenic	0.997
LRP5	O75197-1.2	Y984E	Pathogenic	0.992
LRP5	O75197-1.2	Y984F	Pathogenic	0.506
LRP5	O75197-1.2	Y984G	Pathogenic	0.998
LRP5	O75197-1.2	Y984H	Pathogenic	0.752
LRP5	O75197-1.2	Y984I	Pathogenic	0.988
LRP5	O75197-1.2	Y984K	Pathogenic	0.99
LRP5	O75197-1.2	Y984L	Pathogenic	0.989
LRP5	O75197-1.2	Y984M	Pathogenic	0.993
LRP5	O75197-1.2	Y984N	Pathogenic	0.992
LRP5	O75197-1.2	Y984P	Pathogenic	0.999
LRP5	O75197-1.2	Y984Q	Pathogenic	0.984
LRP5	O75197-1.2	Y984R	Pathogenic	0.99
LRP5	O75197-1.2	Y984S	Pathogenic	0.995
LRP5	O75197-1.2	Y984T	Pathogenic	0.996
LRP5	O75197-1.2	Y984V	Pathogenic	0.993
LRP5	O75197-1.2	Y984W	Pathogenic	0.668
LRP5	O75197-1.2	D985A	Pathogenic	0.996
LRP5	O75197-1.2	D985C	Pathogenic	0.997
LRP5	O75197-1.2	D985E	Pathogenic	0.861
LRP5	O75197-1.2	D985F	Pathogenic	0.994
LRP5	O75197-1.2	D985G	Pathogenic	0.99
LRP5	O75197-1.2	D985H	Pathogenic	0.989
LRP5	O75197-1.2	D985I	Pathogenic	0.994
LRP5	O75197-1.2	D985K	Pathogenic	0.994
LRP5	O75197-1.2	D985L	Pathogenic	0.998
LRP5	O75197-1.2	D985M	Pathogenic	0.997
LRP5	O75197-1.2	D985N	Pathogenic	0.949
LRP5	O75197-1.2	D985P	Pathogenic	0.982
LRP5	O75197-1.2	D985Q	Pathogenic	0.975
LRP5	O75197-1.2	D985R	Pathogenic	0.998
LRP5	O75197-1.2	D985S	Pathogenic	0.971
LRP5	O75197-1.2	D985T	Pathogenic	0.988
LRP5	O75197-1.2	D985V	Pathogenic	0.997
LRP5	O75197-1.2	D985W	Pathogenic	0.997
LRP5	O75197-1.2	D985Y	Pathogenic	0.997
LRP5	O75197-1.2	P986A	Pathogenic	0.989
LRP5	O75197-1.2	P986C	Pathogenic	0.999
LRP5	O75197-1.2	P986D	Pathogenic	0.973
LRP5	O75197-1.2	P986E	Pathogenic	0.975
LRP5	O75197-1.2	P986F	Pathogenic	0.999
LRP5	O75197-1.2	P986G	Pathogenic	0.995
LRP5	O75197-1.2	P986H	Pathogenic	0.996
LRP5	O75197-1.2	P986I	Pathogenic	0.998
LRP5	O75197-1.2	P986K	Pathogenic	0.965
LRP5	O75197-1.2	P986L	Pathogenic	0.998
LRP5	O75197-1.2	P986M	Pathogenic	0.996
LRP5	O75197-1.2	P986N	Pathogenic	0.992
LRP5	O75197-1.2	P986Q	Pathogenic	0.983
LRP5	O75197-1.2	P986R	Pathogenic	0.988
LRP5	O75197-1.2	P986S	Pathogenic	0.985
LRP5	O75197-1.2	P986T	Pathogenic	0.989
LRP5	O75197-1.2	P986V	Pathogenic	0.996
LRP5	O75197-1.2	P986W	Pathogenic	0.999
LRP5	O75197-1.2	P986Y	Pathogenic	0.999
LRP5	O75197-1.2	L987A	Pathogenic	0.656
LRP5	O75197-1.2	L987C	Pathogenic	0.782
LRP5	O75197-1.2	L987D	Pathogenic	0.955
LRP5	O75197-1.2	L987E	Pathogenic	0.89
LRP5	O75197-1.2	L987F	Pathogenic	0.684
LRP5	O75197-1.2	L987G	Pathogenic	0.975
LRP5	O75197-1.2	L987H	Pathogenic	0.942
LRP5	O75197-1.2	L987I	Neutral	0.19
LRP5	O75197-1.2	L987K	Pathogenic	0.661
LRP5	O75197-1.2	L987M	Neutral	0.145
LRP5	O75197-1.2	L987N	Pathogenic	0.891
LRP5	O75197-1.2	L987P	Pathogenic	0.963
LRP5	O75197-1.2	L987Q	Pathogenic	0.796
LRP5	O75197-1.2	L987R	Pathogenic	0.654
LRP5	O75197-1.2	L987S	Pathogenic	0.811
LRP5	O75197-1.2	L987T	Pathogenic	0.655
LRP5	O75197-1.2	L987V	Neutral	0.33
LRP5	O75197-1.2	L987W	Pathogenic	0.927
LRP5	O75197-1.2	L987Y	Pathogenic	0.784
LRP5	O75197-1.2	D988A	Pathogenic	0.906
LRP5	O75197-1.2	D988C	Pathogenic	0.943
LRP5	O75197-1.2	D988E	Neutral	0.21
LRP5	O75197-1.2	D988F	Pathogenic	0.884
LRP5	O75197-1.2	D988G	Pathogenic	0.803
LRP5	O75197-1.2	D988H	Pathogenic	0.788
LRP5	O75197-1.2	D988I	Pathogenic	0.884
LRP5	O75197-1.2	D988K	Pathogenic	0.869
LRP5	O75197-1.2	D988L	Pathogenic	0.962
LRP5	O75197-1.2	D988M	Pathogenic	0.927
LRP5	O75197-1.2	D988N	Neutral	0.444
LRP5	O75197-1.2	D988P	Pathogenic	0.696
LRP5	O75197-1.2	D988Q	Pathogenic	0.627
LRP5	O75197-1.2	D988R	Pathogenic	0.951
LRP5	O75197-1.2	D988S	Pathogenic	0.59
LRP5	O75197-1.2	D988T	Pathogenic	0.775
LRP5	O75197-1.2	D988V	Pathogenic	0.93
LRP5	O75197-1.2	D988W	Pathogenic	0.936
LRP5	O75197-1.2	D988Y	Pathogenic	0.94
LRP5	O75197-1.2	K989A	Pathogenic	0.551
LRP5	O75197-1.2	K989C	Pathogenic	0.865
LRP5	O75197-1.2	K989D	Pathogenic	0.77
LRP5	O75197-1.2	K989E	Neutral	0.248
LRP5	O75197-1.2	K989F	Pathogenic	0.771
LRP5	O75197-1.2	K989G	Pathogenic	0.827
LRP5	O75197-1.2	K989H	Pathogenic	0.609
LRP5	O75197-1.2	K989I	Pathogenic	0.766
LRP5	O75197-1.2	K989L	Pathogenic	0.541
LRP5	O75197-1.2	K989M	Neutral	0.371
LRP5	O75197-1.2	K989N	Neutral	0.488
LRP5	O75197-1.2	K989P	Neutral	0.469
LRP5	O75197-1.2	K989Q	Neutral	0.186
LRP5	O75197-1.2	K989R	Neutral	0.13
LRP5	O75197-1.2	K989S	Neutral	0.357
LRP5	O75197-1.2	K989T	Pathogenic	0.573
LRP5	O75197-1.2	K989V	Pathogenic	0.638
LRP5	O75197-1.2	K989W	Pathogenic	0.681
LRP5	O75197-1.2	K989Y	Pathogenic	0.697
LRP5	O75197-1.2	F990A	Neutral	0.331
LRP5	O75197-1.2	F990C	Neutral	0.483
LRP5	O75197-1.2	F990D	Neutral	0.374
LRP5	O75197-1.2	F990E	Neutral	0.409
LRP5	O75197-1.2	F990G	Pathogenic	0.526
LRP5	O75197-1.2	F990H	Neutral	0.131
LRP5	O75197-1.2	F990I	Neutral	0.179
LRP5	O75197-1.2	F990K	Neutral	0.345
LRP5	O75197-1.2	F990L	Neutral	0.169
LRP5	O75197-1.2	F990M	Neutral	0.118
LRP5	O75197-1.2	F990N	Neutral	0.412
LRP5	O75197-1.2	F990P	Pathogenic	0.873
LRP5	O75197-1.2	F990Q	Pathogenic	0.503
LRP5	O75197-1.2	F990R	Neutral	0.337
LRP5	O75197-1.2	F990S	Neutral	0.269
LRP5	O75197-1.2	F990T	Neutral	0.33
LRP5	O75197-1.2	F990V	Neutral	0.28
LRP5	O75197-1.2	F990W	Neutral	0.045
LRP5	O75197-1.2	F990Y	Neutral	0.004
LRP5	O75197-1.2	I991A	Neutral	0.313
LRP5	O75197-1.2	I991C	Neutral	0.462
LRP5	O75197-1.2	I991D	Pathogenic	0.626
LRP5	O75197-1.2	I991E	Pathogenic	0.66
LRP5	O75197-1.2	I991F	Neutral	0.378
LRP5	O75197-1.2	I991G	Pathogenic	0.904
LRP5	O75197-1.2	I991H	Pathogenic	0.797
LRP5	O75197-1.2	I991K	Pathogenic	0.588
LRP5	O75197-1.2	I991L	Neutral	0.058
LRP5	O75197-1.2	I991M	Neutral	0.11
LRP5	O75197-1.2	I991N	Pathogenic	0.663
LRP5	O75197-1.2	I991P	Pathogenic	0.864
LRP5	O75197-1.2	I991Q	Pathogenic	0.74
LRP5	O75197-1.2	I991R	Pathogenic	0.579
LRP5	O75197-1.2	I991S	Pathogenic	0.507
LRP5	O75197-1.2	I991T	Neutral	0.313
LRP5	O75197-1.2	I991V	Neutral	0.013
LRP5	O75197-1.2	I991W	Pathogenic	0.917
LRP5	O75197-1.2	I991Y	Neutral	0.466
LRP5	O75197-1.2	Y992A	Pathogenic	0.999
LRP5	O75197-1.2	Y992C	Pathogenic	1.0
LRP5	O75197-1.2	Y992D	Pathogenic	0.999
LRP5	O75197-1.2	Y992E	Pathogenic	0.998
LRP5	O75197-1.2	Y992F	Pathogenic	0.824
LRP5	O75197-1.2	Y992G	Pathogenic	1.0
LRP5	O75197-1.2	Y992H	Pathogenic	0.933
LRP5	O75197-1.2	Y992I	Pathogenic	0.997
LRP5	O75197-1.2	Y992K	Pathogenic	0.998
LRP5	O75197-1.2	Y992L	Pathogenic	0.998
LRP5	O75197-1.2	Y992M	Pathogenic	0.998
LRP5	O75197-1.2	Y992N	Pathogenic	0.998
LRP5	O75197-1.2	Y992P	Pathogenic	1.0
LRP5	O75197-1.2	Y992Q	Pathogenic	0.996
LRP5	O75197-1.2	Y992R	Pathogenic	0.998
LRP5	O75197-1.2	Y992S	Pathogenic	0.999
LRP5	O75197-1.2	Y992T	Pathogenic	0.999
LRP5	O75197-1.2	Y992V	Pathogenic	0.998
LRP5	O75197-1.2	Y992W	Pathogenic	0.902
LRP5	O75197-1.2	W993A	Pathogenic	1.0
LRP5	O75197-1.2	W993C	Pathogenic	0.999
LRP5	O75197-1.2	W993D	Pathogenic	1.0
LRP5	O75197-1.2	W993E	Pathogenic	0.999
LRP5	O75197-1.2	W993F	Pathogenic	0.991
LRP5	O75197-1.2	W993G	Pathogenic	0.998
LRP5	O75197-1.2	W993H	Pathogenic	0.999
LRP5	O75197-1.2	W993I	Pathogenic	1.0
LRP5	O75197-1.2	W993K	Pathogenic	0.999
LRP5	O75197-1.2	W993L	Pathogenic	1.0
LRP5	O75197-1.2	W993M	Pathogenic	0.998
LRP5	O75197-1.2	W993N	Pathogenic	1.0
LRP5	O75197-1.2	W993P	Pathogenic	1.0
LRP5	O75197-1.2	W993Q	Pathogenic	0.998
LRP5	O75197-1.2	W993R	Pathogenic	0.999
LRP5	O75197-1.2	W993S	Pathogenic	0.999
LRP5	O75197-1.2	W993T	Pathogenic	0.999
LRP5	O75197-1.2	W993V	Pathogenic	1.0
LRP5	O75197-1.2	W993Y	Pathogenic	0.945
LRP5	O75197-1.2	V994A	Neutral	0.348
LRP5	O75197-1.2	V994C	Pathogenic	0.753
LRP5	O75197-1.2	V994D	Pathogenic	0.856
LRP5	O75197-1.2	V994E	Pathogenic	0.691
LRP5	O75197-1.2	V994F	Pathogenic	0.689
LRP5	O75197-1.2	V994G	Pathogenic	0.917
LRP5	O75197-1.2	V994H	Pathogenic	0.93
LRP5	O75197-1.2	V994I	Neutral	0.025
LRP5	O75197-1.2	V994K	Pathogenic	0.61
LRP5	O75197-1.2	V994L	Neutral	0.209
LRP5	O75197-1.2	V994M	Neutral	0.287
LRP5	O75197-1.2	V994N	Pathogenic	0.875
LRP5	O75197-1.2	V994P	Pathogenic	0.881
LRP5	O75197-1.2	V994Q	Pathogenic	0.763
LRP5	O75197-1.2	V994R	Pathogenic	0.822
LRP5	O75197-1.2	V994S	Pathogenic	0.785
LRP5	O75197-1.2	V994T	Neutral	0.347
LRP5	O75197-1.2	V994W	Pathogenic	0.929
LRP5	O75197-1.2	V994Y	Pathogenic	0.745
LRP5	O75197-1.2	D995A	Pathogenic	0.995
LRP5	O75197-1.2	D995C	Pathogenic	0.997
LRP5	O75197-1.2	D995E	Pathogenic	0.856
LRP5	O75197-1.2	D995F	Pathogenic	0.994
LRP5	O75197-1.2	D995G	Pathogenic	0.989
LRP5	O75197-1.2	D995H	Pathogenic	0.988
LRP5	O75197-1.2	D995I	Pathogenic	0.994
LRP5	O75197-1.2	D995K	Pathogenic	0.993
LRP5	O75197-1.2	D995L	Pathogenic	0.998
LRP5	O75197-1.2	D995M	Pathogenic	0.996
LRP5	O75197-1.2	D995N	Pathogenic	0.947
LRP5	O75197-1.2	D995P	Pathogenic	0.981
LRP5	O75197-1.2	D995Q	Pathogenic	0.974
LRP5	O75197-1.2	D995R	Pathogenic	0.998
LRP5	O75197-1.2	D995S	Pathogenic	0.97
LRP5	O75197-1.2	D995T	Pathogenic	0.987
LRP5	O75197-1.2	D995V	Pathogenic	0.997
LRP5	O75197-1.2	D995W	Pathogenic	0.997
LRP5	O75197-1.2	D995Y	Pathogenic	0.997
LRP5	O75197-1.2	G996A	Pathogenic	0.513
LRP5	O75197-1.2	G996C	Pathogenic	0.94
LRP5	O75197-1.2	G996D	Pathogenic	0.671
LRP5	O75197-1.2	G996E	Pathogenic	0.872
LRP5	O75197-1.2	G996F	Pathogenic	0.876
LRP5	O75197-1.2	G996H	Pathogenic	0.913
LRP5	O75197-1.2	G996I	Pathogenic	0.956
LRP5	O75197-1.2	G996K	Pathogenic	0.826
LRP5	O75197-1.2	G996L	Pathogenic	0.959
LRP5	O75197-1.2	G996M	Pathogenic	0.922
LRP5	O75197-1.2	G996N	Neutral	0.436
LRP5	O75197-1.2	G996P	Pathogenic	0.867
LRP5	O75197-1.2	G996Q	Pathogenic	0.907
LRP5	O75197-1.2	G996R	Pathogenic	0.821
LRP5	O75197-1.2	G996S	Pathogenic	0.571
LRP5	O75197-1.2	G996T	Pathogenic	0.907
LRP5	O75197-1.2	G996V	Pathogenic	0.925
LRP5	O75197-1.2	G996W	Pathogenic	0.595
LRP5	O75197-1.2	G996Y	Pathogenic	0.936
LRP5	O75197-1.2	R997A	Pathogenic	0.947
LRP5	O75197-1.2	R997C	Pathogenic	0.989
LRP5	O75197-1.2	R997D	Pathogenic	0.993
LRP5	O75197-1.2	R997E	Pathogenic	0.936
LRP5	O75197-1.2	R997F	Pathogenic	0.98
LRP5	O75197-1.2	R997G	Pathogenic	0.986
LRP5	O75197-1.2	R997H	Pathogenic	0.882
LRP5	O75197-1.2	R997I	Pathogenic	0.979
LRP5	O75197-1.2	R997K	Pathogenic	0.693
LRP5	O75197-1.2	R997L	Pathogenic	0.945
LRP5	O75197-1.2	R997M	Pathogenic	0.895
LRP5	O75197-1.2	R997N	Pathogenic	0.933
LRP5	O75197-1.2	R997P	Pathogenic	0.975
LRP5	O75197-1.2	R997Q	Pathogenic	0.769
LRP5	O75197-1.2	R997S	Pathogenic	0.961
LRP5	O75197-1.2	R997T	Pathogenic	0.951
LRP5	O75197-1.2	R997V	Pathogenic	0.987
LRP5	O75197-1.2	R997W	Pathogenic	0.97
LRP5	O75197-1.2	R997Y	Pathogenic	0.972
LRP5	O75197-1.2	Q998A	Pathogenic	0.927
LRP5	O75197-1.2	Q998C	Pathogenic	0.985
LRP5	O75197-1.2	Q998D	Pathogenic	0.81
LRP5	O75197-1.2	Q998E	Neutral	0.348
LRP5	O75197-1.2	Q998F	Pathogenic	0.97
LRP5	O75197-1.2	Q998G	Pathogenic	0.98
LRP5	O75197-1.2	Q998H	Pathogenic	0.84
LRP5	O75197-1.2	Q998I	Pathogenic	0.97
LRP5	O75197-1.2	Q998K	Pathogenic	0.536
LRP5	O75197-1.2	Q998L	Pathogenic	0.922
LRP5	O75197-1.2	Q998M	Pathogenic	0.66
LRP5	O75197-1.2	Q998N	Pathogenic	0.833
LRP5	O75197-1.2	Q998P	Pathogenic	0.902
LRP5	O75197-1.2	Q998R	Pathogenic	0.528
LRP5	O75197-1.2	Q998S	Pathogenic	0.852
LRP5	O75197-1.2	Q998T	Pathogenic	0.933
LRP5	O75197-1.2	Q998V	Pathogenic	0.948
LRP5	O75197-1.2	Q998W	Pathogenic	0.872
LRP5	O75197-1.2	Q998Y	Pathogenic	0.88
LRP5	O75197-1.2	N999A	Pathogenic	0.942
LRP5	O75197-1.2	N999C	Pathogenic	0.965
LRP5	O75197-1.2	N999D	Pathogenic	0.536
LRP5	O75197-1.2	N999E	Pathogenic	0.796
LRP5	O75197-1.2	N999F	Pathogenic	0.928
LRP5	O75197-1.2	N999G	Pathogenic	0.69
LRP5	O75197-1.2	N999H	Neutral	0.404
LRP5	O75197-1.2	N999I	Pathogenic	0.928
LRP5	O75197-1.2	N999K	Pathogenic	0.732
LRP5	O75197-1.2	N999L	Pathogenic	0.934
LRP5	O75197-1.2	N999M	Pathogenic	0.876
LRP5	O75197-1.2	N999P	Pathogenic	0.921
LRP5	O75197-1.2	N999Q	Pathogenic	0.74
LRP5	O75197-1.2	N999R	Pathogenic	0.725
LRP5	O75197-1.2	N999S	Neutral	0.441
LRP5	O75197-1.2	N999T	Pathogenic	0.656
LRP5	O75197-1.2	N999V	Pathogenic	0.957
LRP5	O75197-1.2	N999W	Pathogenic	0.961
LRP5	O75197-1.2	N999Y	Pathogenic	0.898
LRP5	O75197-1.2	I1000A	Pathogenic	0.986
LRP5	O75197-1.2	I1000C	Pathogenic	0.992
LRP5	O75197-1.2	I1000D	Pathogenic	0.996
LRP5	O75197-1.2	I1000E	Pathogenic	0.997
LRP5	O75197-1.2	I1000F	Pathogenic	0.989
LRP5	O75197-1.2	I1000G	Pathogenic	0.999
LRP5	O75197-1.2	I1000H	Pathogenic	0.998
LRP5	O75197-1.2	I1000K	Pathogenic	0.995
LRP5	O75197-1.2	I1000L	Pathogenic	0.904
LRP5	O75197-1.2	I1000M	Pathogenic	0.949
LRP5	O75197-1.2	I1000N	Pathogenic	0.997
LRP5	O75197-1.2	I1000P	Pathogenic	0.999
LRP5	O75197-1.2	I1000Q	Pathogenic	0.998
LRP5	O75197-1.2	I1000R	Pathogenic	0.995
LRP5	O75197-1.2	I1000S	Pathogenic	0.994
LRP5	O75197-1.2	I1000T	Pathogenic	0.986
LRP5	O75197-1.2	I1000V	Pathogenic	0.66
LRP5	O75197-1.2	I1000W	Pathogenic	0.999
LRP5	O75197-1.2	I1000Y	Pathogenic	0.993
LRP5	O75197-1.2	K1001A	Pathogenic	0.798
LRP5	O75197-1.2	K1001C	Pathogenic	0.954
LRP5	O75197-1.2	K1001D	Pathogenic	0.915
LRP5	O75197-1.2	K1001E	Pathogenic	0.516
LRP5	O75197-1.2	K1001F	Pathogenic	0.916
LRP5	O75197-1.2	K1001G	Pathogenic	0.939
LRP5	O75197-1.2	K1001H	Pathogenic	0.834
LRP5	O75197-1.2	K1001I	Pathogenic	0.913
LRP5	O75197-1.2	K1001L	Pathogenic	0.791
LRP5	O75197-1.2	K1001M	Pathogenic	0.655
LRP5	O75197-1.2	K1001N	Pathogenic	0.754
LRP5	O75197-1.2	K1001P	Pathogenic	0.74
LRP5	O75197-1.2	K1001Q	Neutral	0.425
LRP5	O75197-1.2	K1001R	Neutral	0.326
LRP5	O75197-1.2	K1001S	Pathogenic	0.641
LRP5	O75197-1.2	K1001T	Pathogenic	0.812
LRP5	O75197-1.2	K1001V	Pathogenic	0.85
LRP5	O75197-1.2	K1001W	Pathogenic	0.873
LRP5	O75197-1.2	K1001Y	Pathogenic	0.881
LRP5	O75197-1.2	R1002A	Pathogenic	0.826
LRP5	O75197-1.2	R1002C	Pathogenic	0.961
LRP5	O75197-1.2	R1002D	Pathogenic	0.975
LRP5	O75197-1.2	R1002E	Pathogenic	0.796
LRP5	O75197-1.2	R1002F	Pathogenic	0.929
LRP5	O75197-1.2	R1002G	Pathogenic	0.949
LRP5	O75197-1.2	R1002H	Pathogenic	0.665
LRP5	O75197-1.2	R1002I	Pathogenic	0.927
LRP5	O75197-1.2	R1002K	Neutral	0.376
LRP5	O75197-1.2	R1002L	Pathogenic	0.82
LRP5	O75197-1.2	R1002M	Pathogenic	0.696
LRP5	O75197-1.2	R1002N	Pathogenic	0.787
LRP5	O75197-1.2	R1002P	Pathogenic	0.912
LRP5	O75197-1.2	R1002Q	Neutral	0.471
LRP5	O75197-1.2	R1002S	Pathogenic	0.867
LRP5	O75197-1.2	R1002T	Pathogenic	0.839
LRP5	O75197-1.2	R1002V	Pathogenic	0.954
LRP5	O75197-1.2	R1002W	Pathogenic	0.896
LRP5	O75197-1.2	R1002Y	Pathogenic	0.901
LRP5	O75197-1.2	A1003C	Pathogenic	0.926
LRP5	O75197-1.2	A1003D	Pathogenic	0.988
LRP5	O75197-1.2	A1003E	Pathogenic	0.967
LRP5	O75197-1.2	A1003F	Pathogenic	0.981
LRP5	O75197-1.2	A1003G	Pathogenic	0.946
LRP5	O75197-1.2	A1003H	Pathogenic	0.994
LRP5	O75197-1.2	A1003I	Pathogenic	0.945
LRP5	O75197-1.2	A1003K	Pathogenic	0.953
LRP5	O75197-1.2	A1003L	Pathogenic	0.95
LRP5	O75197-1.2	A1003M	Pathogenic	0.966
LRP5	O75197-1.2	A1003N	Pathogenic	0.989
LRP5	O75197-1.2	A1003P	Pathogenic	0.98
LRP5	O75197-1.2	A1003Q	Pathogenic	0.977
LRP5	O75197-1.2	A1003R	Pathogenic	0.951
LRP5	O75197-1.2	A1003S	Pathogenic	0.85
LRP5	O75197-1.2	A1003T	Pathogenic	0.956
LRP5	O75197-1.2	A1003V	Pathogenic	0.908
LRP5	O75197-1.2	A1003W	Pathogenic	0.99
LRP5	O75197-1.2	A1003Y	Pathogenic	0.991
LRP5	O75197-1.2	K1004A	Neutral	0.086
LRP5	O75197-1.2	K1004C	Neutral	0.33
LRP5	O75197-1.2	K1004D	Neutral	0.205
LRP5	O75197-1.2	K1004E	Neutral	0.025
LRP5	O75197-1.2	K1004F	Neutral	0.206
LRP5	O75197-1.2	K1004G	Neutral	0.269
LRP5	O75197-1.2	K1004H	Neutral	0.107
LRP5	O75197-1.2	K1004I	Neutral	0.201
LRP5	O75197-1.2	K1004L	Neutral	0.083
LRP5	O75197-1.2	K1004M	Neutral	0.043
LRP5	O75197-1.2	K1004N	Neutral	0.068
LRP5	O75197-1.2	K1004P	Neutral	0.064
LRP5	O75197-1.2	K1004Q	Neutral	0.017
LRP5	O75197-1.2	K1004R	Neutral	0.011
LRP5	O75197-1.2	K1004S	Neutral	0.041
LRP5	O75197-1.2	K1004T	Neutral	0.094
LRP5	O75197-1.2	K1004V	Neutral	0.119
LRP5	O75197-1.2	K1004W	Neutral	0.141
LRP5	O75197-1.2	K1004Y	Neutral	0.151
LRP5	O75197-1.2	D1005A	Pathogenic	0.799
LRP5	O75197-1.2	D1005C	Pathogenic	0.872
LRP5	O75197-1.2	D1005E	Neutral	0.098
LRP5	O75197-1.2	D1005F	Pathogenic	0.757
LRP5	O75197-1.2	D1005G	Pathogenic	0.625
LRP5	O75197-1.2	D1005H	Pathogenic	0.603
LRP5	O75197-1.2	D1005I	Pathogenic	0.758
LRP5	O75197-1.2	D1005K	Pathogenic	0.731
LRP5	O75197-1.2	D1005L	Pathogenic	0.912
LRP5	O75197-1.2	D1005M	Pathogenic	0.839
LRP5	O75197-1.2	D1005N	Neutral	0.247
LRP5	O75197-1.2	D1005P	Neutral	0.484
LRP5	O75197-1.2	D1005Q	Neutral	0.408
LRP5	O75197-1.2	D1005R	Pathogenic	0.889
LRP5	O75197-1.2	D1005S	Neutral	0.371
LRP5	O75197-1.2	D1005T	Pathogenic	0.586
LRP5	O75197-1.2	D1005V	Pathogenic	0.845
LRP5	O75197-1.2	D1005W	Pathogenic	0.857
LRP5	O75197-1.2	D1005Y	Pathogenic	0.866
LRP5	O75197-1.2	D1006A	Pathogenic	0.97
LRP5	O75197-1.2	D1006C	Pathogenic	0.983
LRP5	O75197-1.2	D1006E	Neutral	0.474
LRP5	O75197-1.2	D1006F	Pathogenic	0.963
LRP5	O75197-1.2	D1006G	Pathogenic	0.932
LRP5	O75197-1.2	D1006H	Pathogenic	0.926
LRP5	O75197-1.2	D1006I	Pathogenic	0.963
LRP5	O75197-1.2	D1006K	Pathogenic	0.957
LRP5	O75197-1.2	D1006L	Pathogenic	0.989
LRP5	O75197-1.2	D1006M	Pathogenic	0.977
LRP5	O75197-1.2	D1006N	Pathogenic	0.73
LRP5	O75197-1.2	D1006P	Pathogenic	0.886
LRP5	O75197-1.2	D1006Q	Pathogenic	0.851
LRP5	O75197-1.2	D1006R	Pathogenic	0.985
LRP5	O75197-1.2	D1006S	Pathogenic	0.83
LRP5	O75197-1.2	D1006T	Pathogenic	0.921
LRP5	O75197-1.2	D1006V	Pathogenic	0.978
LRP5	O75197-1.2	D1006W	Pathogenic	0.98
LRP5	O75197-1.2	D1006Y	Pathogenic	0.982
LRP5	O75197-1.2	G1007A	Pathogenic	0.945
LRP5	O75197-1.2	G1007C	Pathogenic	0.996
LRP5	O75197-1.2	G1007D	Pathogenic	0.971
LRP5	O75197-1.2	G1007E	Pathogenic	0.991
LRP5	O75197-1.2	G1007F	Pathogenic	0.991
LRP5	O75197-1.2	G1007H	Pathogenic	0.994
LRP5	O75197-1.2	G1007I	Pathogenic	0.997
LRP5	O75197-1.2	G1007K	Pathogenic	0.987
LRP5	O75197-1.2	G1007L	Pathogenic	0.997
LRP5	O75197-1.2	G1007M	Pathogenic	0.995
LRP5	O75197-1.2	G1007N	Pathogenic	0.926
LRP5	O75197-1.2	G1007P	Pathogenic	0.991
LRP5	O75197-1.2	G1007Q	Pathogenic	0.994
LRP5	O75197-1.2	G1007R	Pathogenic	0.987
LRP5	O75197-1.2	G1007S	Pathogenic	0.956
LRP5	O75197-1.2	G1007T	Pathogenic	0.994
LRP5	O75197-1.2	G1007V	Pathogenic	0.995
LRP5	O75197-1.2	G1007W	Pathogenic	0.96
LRP5	O75197-1.2	G1007Y	Pathogenic	0.996
LRP5	O75197-1.2	T1008A	Neutral	0.314
LRP5	O75197-1.2	T1008C	Neutral	0.439
LRP5	O75197-1.2	T1008D	Neutral	0.377
LRP5	O75197-1.2	T1008E	Neutral	0.399
LRP5	O75197-1.2	T1008F	Pathogenic	0.523
LRP5	O75197-1.2	T1008G	Pathogenic	0.773
LRP5	O75197-1.2	T1008H	Pathogenic	0.799
LRP5	O75197-1.2	T1008I	Neutral	0.266
LRP5	O75197-1.2	T1008K	Neutral	0.318
LRP5	O75197-1.2	T1008L	Neutral	0.284
LRP5	O75197-1.2	T1008M	Neutral	0.376
LRP5	O75197-1.2	T1008N	Neutral	0.187
LRP5	O75197-1.2	T1008P	Neutral	0.5
LRP5	O75197-1.2	T1008Q	Neutral	0.489
LRP5	O75197-1.2	T1008R	Neutral	0.31
LRP5	O75197-1.2	T1008S	Neutral	0.109
LRP5	O75197-1.2	T1008V	Neutral	0.172
LRP5	O75197-1.2	T1008W	Neutral	0.41
LRP5	O75197-1.2	T1008Y	Pathogenic	0.695
LRP5	O75197-1.2	Q1009A	Pathogenic	0.957
LRP5	O75197-1.2	Q1009C	Pathogenic	0.992
LRP5	O75197-1.2	Q1009D	Pathogenic	0.883
LRP5	O75197-1.2	Q1009E	Neutral	0.486
LRP5	O75197-1.2	Q1009F	Pathogenic	0.983
LRP5	O75197-1.2	Q1009G	Pathogenic	0.989
LRP5	O75197-1.2	Q1009H	Pathogenic	0.903
LRP5	O75197-1.2	Q1009I	Pathogenic	0.983
LRP5	O75197-1.2	Q1009K	Pathogenic	0.671
LRP5	O75197-1.2	Q1009L	Pathogenic	0.954
LRP5	O75197-1.2	Q1009M	Pathogenic	0.775
LRP5	O75197-1.2	Q1009N	Pathogenic	0.898
LRP5	O75197-1.2	Q1009P	Pathogenic	0.942
LRP5	O75197-1.2	Q1009R	Pathogenic	0.664
LRP5	O75197-1.2	Q1009S	Pathogenic	0.91
LRP5	O75197-1.2	Q1009T	Pathogenic	0.961
LRP5	O75197-1.2	Q1009V	Pathogenic	0.97
LRP5	O75197-1.2	Q1009W	Pathogenic	0.923
LRP5	O75197-1.2	Q1009Y	Pathogenic	0.928
LRP5	O75197-1.2	P1010A	Neutral	0.075
LRP5	O75197-1.2	P1010C	Neutral	0.469
LRP5	O75197-1.2	P1010D	Neutral	0.031
LRP5	O75197-1.2	P1010E	Neutral	0.034
LRP5	O75197-1.2	P1010F	Pathogenic	0.551
LRP5	O75197-1.2	P1010G	Neutral	0.154
LRP5	O75197-1.2	P1010H	Neutral	0.173
LRP5	O75197-1.2	P1010I	Neutral	0.288
LRP5	O75197-1.2	P1010K	Neutral	0.024
LRP5	O75197-1.2	P1010L	Neutral	0.307
LRP5	O75197-1.2	P1010M	Neutral	0.182
LRP5	O75197-1.2	P1010N	Neutral	0.101
LRP5	O75197-1.2	P1010Q	Neutral	0.048
LRP5	O75197-1.2	P1010R	Neutral	0.067
LRP5	O75197-1.2	P1010S	Neutral	0.057
LRP5	O75197-1.2	P1010T	Neutral	0.074
LRP5	O75197-1.2	P1010V	Neutral	0.188
LRP5	O75197-1.2	P1010W	Neutral	0.437
LRP5	O75197-1.2	P1010Y	Neutral	0.456
LRP5	O75197-1.2	F1011A	Neutral	0.306
LRP5	O75197-1.2	F1011C	Neutral	0.454
LRP5	O75197-1.2	F1011D	Neutral	0.348
LRP5	O75197-1.2	F1011E	Neutral	0.382
LRP5	O75197-1.2	F1011G	Neutral	0.497
LRP5	O75197-1.2	F1011H	Neutral	0.119
LRP5	O75197-1.2	F1011I	Neutral	0.163
LRP5	O75197-1.2	F1011K	Neutral	0.32
LRP5	O75197-1.2	F1011L	Neutral	0.154
LRP5	O75197-1.2	F1011M	Neutral	0.107
LRP5	O75197-1.2	F1011N	Neutral	0.384
LRP5	O75197-1.2	F1011P	Pathogenic	0.86
LRP5	O75197-1.2	F1011Q	Neutral	0.475
LRP5	O75197-1.2	F1011R	Neutral	0.312
LRP5	O75197-1.2	F1011S	Neutral	0.247
LRP5	O75197-1.2	F1011T	Neutral	0.306
LRP5	O75197-1.2	F1011V	Neutral	0.258
LRP5	O75197-1.2	F1011W	Neutral	0.04
LRP5	O75197-1.2	F1011Y	Neutral	0.003
LRP5	O75197-1.2	V1012A	Pathogenic	0.516
LRP5	O75197-1.2	V1012C	Pathogenic	0.86
LRP5	O75197-1.2	V1012D	Pathogenic	0.923
LRP5	O75197-1.2	V1012E	Pathogenic	0.817
LRP5	O75197-1.2	V1012F	Pathogenic	0.816
LRP5	O75197-1.2	V1012G	Pathogenic	0.957
LRP5	O75197-1.2	V1012H	Pathogenic	0.964
LRP5	O75197-1.2	V1012I	Neutral	0.05
LRP5	O75197-1.2	V1012K	Pathogenic	0.758
LRP5	O75197-1.2	V1012L	Neutral	0.346
LRP5	O75197-1.2	V1012M	Neutral	0.446
LRP5	O75197-1.2	V1012N	Pathogenic	0.933
LRP5	O75197-1.2	V1012P	Pathogenic	0.937
LRP5	O75197-1.2	V1012Q	Pathogenic	0.866
LRP5	O75197-1.2	V1012R	Pathogenic	0.902
LRP5	O75197-1.2	V1012S	Pathogenic	0.88
LRP5	O75197-1.2	V1012T	Pathogenic	0.515
LRP5	O75197-1.2	V1012W	Pathogenic	0.963
LRP5	O75197-1.2	V1012Y	Pathogenic	0.854
LRP5	O75197-1.2	L1013A	Neutral	0.07
LRP5	O75197-1.2	L1013C	Neutral	0.124
LRP5	O75197-1.2	L1013D	Neutral	0.457
LRP5	O75197-1.2	L1013E	Neutral	0.243
LRP5	O75197-1.2	L1013F	Neutral	0.079
LRP5	O75197-1.2	L1013G	Pathogenic	0.61
LRP5	O75197-1.2	L1013H	Neutral	0.393
LRP5	O75197-1.2	L1013I	Neutral	0.009
LRP5	O75197-1.2	L1013K	Neutral	0.072
LRP5	O75197-1.2	L1013M	Neutral	0.007
LRP5	O75197-1.2	L1013N	Neutral	0.245
LRP5	O75197-1.2	L1013P	Pathogenic	0.511
LRP5	O75197-1.2	L1013Q	Neutral	0.134
LRP5	O75197-1.2	L1013R	Neutral	0.07
LRP5	O75197-1.2	L1013S	Neutral	0.145
LRP5	O75197-1.2	L1013T	Neutral	0.07
LRP5	O75197-1.2	L1013V	Neutral	0.019
LRP5	O75197-1.2	L1013W	Neutral	0.334
LRP5	O75197-1.2	L1013Y	Neutral	0.126
LRP5	O75197-1.2	T1014A	Neutral	0.069
LRP5	O75197-1.2	T1014C	Neutral	0.114
LRP5	O75197-1.2	T1014D	Neutral	0.09
LRP5	O75197-1.2	T1014E	Neutral	0.098
LRP5	O75197-1.2	T1014F	Neutral	0.152
LRP5	O75197-1.2	T1014G	Neutral	0.358
LRP5	O75197-1.2	T1014H	Neutral	0.393
LRP5	O75197-1.2	T1014I	Neutral	0.056
LRP5	O75197-1.2	T1014K	Neutral	0.071
LRP5	O75197-1.2	T1014L	Neutral	0.061
LRP5	O75197-1.2	T1014M	Neutral	0.09
LRP5	O75197-1.2	T1014N	Neutral	0.036
LRP5	O75197-1.2	T1014P	Neutral	0.14
LRP5	O75197-1.2	T1014Q	Neutral	0.135
LRP5	O75197-1.2	T1014R	Neutral	0.068
LRP5	O75197-1.2	T1014S	Neutral	0.02
LRP5	O75197-1.2	T1014V	Neutral	0.033
LRP5	O75197-1.2	T1014W	Neutral	0.102
LRP5	O75197-1.2	T1014Y	Neutral	0.271
LRP5	O75197-1.2	S1015A	Neutral	0.072
LRP5	O75197-1.2	S1015C	Neutral	0.281
LRP5	O75197-1.2	S1015D	Neutral	0.141
LRP5	O75197-1.2	S1015E	Neutral	0.152
LRP5	O75197-1.2	S1015F	Neutral	0.348
LRP5	O75197-1.2	S1015G	Neutral	0.233
LRP5	O75197-1.2	S1015H	Neutral	0.443
LRP5	O75197-1.2	S1015I	Neutral	0.349
LRP5	O75197-1.2	S1015K	Neutral	0.112
LRP5	O75197-1.2	S1015L	Neutral	0.37
LRP5	O75197-1.2	S1015M	Neutral	0.227
LRP5	O75197-1.2	S1015N	Neutral	0.059
LRP5	O75197-1.2	S1015P	Neutral	0.33
LRP5	O75197-1.2	S1015Q	Neutral	0.206
LRP5	O75197-1.2	S1015R	Neutral	0.27
LRP5	O75197-1.2	S1015T	Neutral	0.074
LRP5	O75197-1.2	S1015V	Neutral	0.483
LRP5	O75197-1.2	S1015W	Pathogenic	0.507
LRP5	O75197-1.2	S1015Y	Pathogenic	0.526
LRP5	O75197-1.2	L1016A	Neutral	0.001
LRP5	O75197-1.2	L1016C	Neutral	0.002
LRP5	O75197-1.2	L1016D	Neutral	0.014
LRP5	O75197-1.2	L1016E	Neutral	0.005
LRP5	O75197-1.2	L1016F	Neutral	0.001
LRP5	O75197-1.2	L1016G	Neutral	0.026
LRP5	O75197-1.2	L1016H	Neutral	0.011
LRP5	O75197-1.2	L1016I	Neutral	0.0
LRP5	O75197-1.2	L1016K	Neutral	0.001
LRP5	O75197-1.2	L1016M	Neutral	0.0
LRP5	O75197-1.2	L1016N	Neutral	0.006
LRP5	O75197-1.2	L1016P	Neutral	0.018
LRP5	O75197-1.2	L1016Q	Neutral	0.003
LRP5	O75197-1.2	L1016R	Neutral	0.001
LRP5	O75197-1.2	L1016S	Neutral	0.003
LRP5	O75197-1.2	L1016T	Neutral	0.001
LRP5	O75197-1.2	L1016V	Neutral	0.0
LRP5	O75197-1.2	L1016W	Neutral	0.009
LRP5	O75197-1.2	L1016Y	Neutral	0.002
LRP5	O75197-1.2	S1017A	Neutral	0.002
LRP5	O75197-1.2	S1017C	Neutral	0.011
LRP5	O75197-1.2	S1017D	Neutral	0.005
LRP5	O75197-1.2	S1017E	Neutral	0.005
LRP5	O75197-1.2	S1017F	Neutral	0.015
LRP5	O75197-1.2	S1017G	Neutral	0.008
LRP5	O75197-1.2	S1017H	Neutral	0.022
LRP5	O75197-1.2	S1017I	Neutral	0.015
LRP5	O75197-1.2	S1017K	Neutral	0.004
LRP5	O75197-1.2	S1017L	Neutral	0.016
LRP5	O75197-1.2	S1017M	Neutral	0.008
LRP5	O75197-1.2	S1017N	Neutral	0.002
LRP5	O75197-1.2	S1017P	Neutral	0.014
LRP5	O75197-1.2	S1017Q	Neutral	0.007
LRP5	O75197-1.2	S1017R	Neutral	0.01
LRP5	O75197-1.2	S1017T	Neutral	0.002
LRP5	O75197-1.2	S1017V	Neutral	0.026
LRP5	O75197-1.2	S1017W	Neutral	0.028
LRP5	O75197-1.2	S1017Y	Neutral	0.03
LRP5	O75197-1.2	Q1018A	Neutral	0.067
LRP5	O75197-1.2	Q1018C	Neutral	0.272
LRP5	O75197-1.2	Q1018D	Neutral	0.023
LRP5	O75197-1.2	Q1018E	Neutral	0.003
LRP5	O75197-1.2	Q1018F	Neutral	0.155
LRP5	O75197-1.2	Q1018G	Neutral	0.218
LRP5	O75197-1.2	Q1018H	Neutral	0.029
LRP5	O75197-1.2	Q1018I	Neutral	0.156
LRP5	O75197-1.2	Q1018K	Neutral	0.006
LRP5	O75197-1.2	Q1018L	Neutral	0.062
LRP5	O75197-1.2	Q1018M	Neutral	0.011
LRP5	O75197-1.2	Q1018N	Neutral	0.027
LRP5	O75197-1.2	Q1018P	Neutral	0.049
LRP5	O75197-1.2	Q1018R	Neutral	0.006
LRP5	O75197-1.2	Q1018S	Neutral	0.031
LRP5	O75197-1.2	Q1018T	Neutral	0.073
LRP5	O75197-1.2	Q1018V	Neutral	0.093
LRP5	O75197-1.2	Q1018W	Neutral	0.037
LRP5	O75197-1.2	Q1018Y	Neutral	0.04
LRP5	O75197-1.2	G1019A	Neutral	0.007
LRP5	O75197-1.2	G1019C	Neutral	0.089
LRP5	O75197-1.2	G1019D	Neutral	0.013
LRP5	O75197-1.2	G1019E	Neutral	0.041
LRP5	O75197-1.2	G1019F	Neutral	0.042
LRP5	O75197-1.2	G1019H	Neutral	0.061
LRP5	O75197-1.2	G1019I	Neutral	0.119
LRP5	O75197-1.2	G1019K	Neutral	0.029
LRP5	O75197-1.2	G1019L	Neutral	0.128
LRP5	O75197-1.2	G1019M	Neutral	0.069
LRP5	O75197-1.2	G1019N	Neutral	0.005
LRP5	O75197-1.2	G1019P	Neutral	0.039
LRP5	O75197-1.2	G1019Q	Neutral	0.057
LRP5	O75197-1.2	G1019R	Neutral	0.028
LRP5	O75197-1.2	G1019S	Neutral	0.008
LRP5	O75197-1.2	G1019T	Neutral	0.057
LRP5	O75197-1.2	G1019V	Neutral	0.072
LRP5	O75197-1.2	G1019W	Neutral	0.009
LRP5	O75197-1.2	G1019Y	Neutral	0.084
LRP5	O75197-1.2	Q1020A	Pathogenic	0.692
LRP5	O75197-1.2	Q1020C	Pathogenic	0.922
LRP5	O75197-1.2	Q1020D	Neutral	0.43
LRP5	O75197-1.2	Q1020E	Neutral	0.086
LRP5	O75197-1.2	Q1020F	Pathogenic	0.852
LRP5	O75197-1.2	Q1020G	Pathogenic	0.897
LRP5	O75197-1.2	Q1020H	Neutral	0.481
LRP5	O75197-1.2	Q1020I	Pathogenic	0.853
LRP5	O75197-1.2	Q1020K	Neutral	0.17
LRP5	O75197-1.2	Q1020L	Pathogenic	0.676
LRP5	O75197-1.2	Q1020M	Neutral	0.256
LRP5	O75197-1.2	Q1020N	Neutral	0.469
LRP5	O75197-1.2	Q1020P	Pathogenic	0.618
LRP5	O75197-1.2	Q1020R	Neutral	0.165
LRP5	O75197-1.2	Q1020S	Pathogenic	0.504
LRP5	O75197-1.2	Q1020T	Pathogenic	0.711
LRP5	O75197-1.2	Q1020V	Pathogenic	0.763
LRP5	O75197-1.2	Q1020W	Pathogenic	0.546
LRP5	O75197-1.2	Q1020Y	Pathogenic	0.564
LRP5	O75197-1.2	N1021A	Neutral	0.469
LRP5	O75197-1.2	N1021C	Pathogenic	0.602
LRP5	O75197-1.2	N1021D	Neutral	0.059
LRP5	O75197-1.2	N1021E	Neutral	0.176
LRP5	O75197-1.2	N1021F	Neutral	0.413
LRP5	O75197-1.2	N1021G	Neutral	0.109
LRP5	O75197-1.2	N1021H	Neutral	0.036
LRP5	O75197-1.2	N1021I	Neutral	0.414
LRP5	O75197-1.2	N1021K	Neutral	0.13
LRP5	O75197-1.2	N1021L	Neutral	0.436
LRP5	O75197-1.2	N1021M	Neutral	0.279
LRP5	O75197-1.2	N1021P	Neutral	0.388
LRP5	O75197-1.2	N1021Q	Neutral	0.135
LRP5	O75197-1.2	N1021R	Neutral	0.126
LRP5	O75197-1.2	N1021S	Neutral	0.041
LRP5	O75197-1.2	N1021T	Neutral	0.094
LRP5	O75197-1.2	N1021V	Pathogenic	0.552
LRP5	O75197-1.2	N1021W	Pathogenic	0.575
LRP5	O75197-1.2	N1021Y	Neutral	0.324
LRP5	O75197-1.2	P1022A	Neutral	0.156
LRP5	O75197-1.2	P1022C	Pathogenic	0.669
LRP5	O75197-1.2	P1022D	Neutral	0.068
LRP5	O75197-1.2	P1022E	Neutral	0.074
LRP5	O75197-1.2	P1022F	Pathogenic	0.736
LRP5	O75197-1.2	P1022G	Neutral	0.294
LRP5	O75197-1.2	P1022H	Neutral	0.323
LRP5	O75197-1.2	P1022I	Neutral	0.48
LRP5	O75197-1.2	P1022K	Neutral	0.053
LRP5	O75197-1.2	P1022L	Pathogenic	0.503
LRP5	O75197-1.2	P1022M	Neutral	0.336
LRP5	O75197-1.2	P1022N	Neutral	0.205
LRP5	O75197-1.2	P1022Q	Neutral	0.104
LRP5	O75197-1.2	P1022R	Neutral	0.142
LRP5	O75197-1.2	P1022S	Neutral	0.121
LRP5	O75197-1.2	P1022T	Neutral	0.155
LRP5	O75197-1.2	P1022V	Neutral	0.346
LRP5	O75197-1.2	P1022W	Pathogenic	0.639
LRP5	O75197-1.2	P1022Y	Pathogenic	0.656
LRP5	O75197-1.2	D1023A	Neutral	0.325
LRP5	O75197-1.2	D1023C	Neutral	0.453
LRP5	O75197-1.2	D1023E	Neutral	0.013
LRP5	O75197-1.2	D1023F	Neutral	0.274
LRP5	O75197-1.2	D1023G	Neutral	0.168
LRP5	O75197-1.2	D1023H	Neutral	0.156
LRP5	O75197-1.2	D1023I	Neutral	0.275
LRP5	O75197-1.2	D1023K	Neutral	0.249
LRP5	O75197-1.2	D1023L	Pathogenic	0.559
LRP5	O75197-1.2	D1023M	Neutral	0.388
LRP5	O75197-1.2	D1023N	Neutral	0.038
LRP5	O75197-1.2	D1023P	Neutral	0.102
LRP5	O75197-1.2	D1023Q	Neutral	0.077
LRP5	O75197-1.2	D1023R	Neutral	0.493
LRP5	O75197-1.2	D1023S	Neutral	0.067
LRP5	O75197-1.2	D1023T	Neutral	0.147
LRP5	O75197-1.2	D1023V	Neutral	0.398
LRP5	O75197-1.2	D1023W	Neutral	0.421
LRP5	O75197-1.2	D1023Y	Neutral	0.44
LRP5	O75197-1.2	R1024A	Neutral	0.003
LRP5	O75197-1.2	R1024C	Neutral	0.018
LRP5	O75197-1.2	R1024D	Neutral	0.028
LRP5	O75197-1.2	R1024E	Neutral	0.003
LRP5	O75197-1.2	R1024F	Neutral	0.01
LRP5	O75197-1.2	R1024G	Neutral	0.013
LRP5	O75197-1.2	R1024H	Neutral	0.001
LRP5	O75197-1.2	R1024I	Neutral	0.009
LRP5	O75197-1.2	R1024K	Neutral	0.0
LRP5	O75197-1.2	R1024L	Neutral	0.003
LRP5	O75197-1.2	R1024M	Neutral	0.002
LRP5	O75197-1.2	R1024N	Neutral	0.003
LRP5	O75197-1.2	R1024P	Neutral	0.008
LRP5	O75197-1.2	R1024Q	Neutral	0.001
LRP5	O75197-1.2	R1024S	Neutral	0.005
LRP5	O75197-1.2	R1024T	Neutral	0.004
LRP5	O75197-1.2	R1024V	Neutral	0.015
LRP5	O75197-1.2	R1024W	Neutral	0.006
LRP5	O75197-1.2	R1024Y	Neutral	0.007
LRP5	O75197-1.2	Q1025A	Pathogenic	0.96
LRP5	O75197-1.2	Q1025C	Pathogenic	0.992
LRP5	O75197-1.2	Q1025D	Pathogenic	0.89
LRP5	O75197-1.2	Q1025E	Pathogenic	0.503
LRP5	O75197-1.2	Q1025F	Pathogenic	0.984
LRP5	O75197-1.2	Q1025G	Pathogenic	0.989
LRP5	O75197-1.2	Q1025H	Pathogenic	0.909
LRP5	O75197-1.2	Q1025I	Pathogenic	0.984
LRP5	O75197-1.2	Q1025K	Pathogenic	0.686
LRP5	O75197-1.2	Q1025L	Pathogenic	0.957
LRP5	O75197-1.2	Q1025M	Pathogenic	0.786
LRP5	O75197-1.2	Q1025N	Pathogenic	0.904
LRP5	O75197-1.2	Q1025P	Pathogenic	0.945
LRP5	O75197-1.2	Q1025R	Pathogenic	0.679
LRP5	O75197-1.2	Q1025S	Pathogenic	0.916
LRP5	O75197-1.2	Q1025T	Pathogenic	0.963
LRP5	O75197-1.2	Q1025V	Pathogenic	0.972
LRP5	O75197-1.2	Q1025W	Pathogenic	0.928
LRP5	O75197-1.2	Q1025Y	Pathogenic	0.933
LRP5	O75197-1.2	P1026A	Pathogenic	0.98
LRP5	O75197-1.2	P1026C	Pathogenic	0.998
LRP5	O75197-1.2	P1026D	Pathogenic	0.95
LRP5	O75197-1.2	P1026E	Pathogenic	0.954
LRP5	O75197-1.2	P1026F	Pathogenic	0.999
LRP5	O75197-1.2	P1026G	Pathogenic	0.991
LRP5	O75197-1.2	P1026H	Pathogenic	0.992
LRP5	O75197-1.2	P1026I	Pathogenic	0.996
LRP5	O75197-1.2	P1026K	Pathogenic	0.935
LRP5	O75197-1.2	P1026L	Pathogenic	0.996
LRP5	O75197-1.2	P1026M	Pathogenic	0.992
LRP5	O75197-1.2	P1026N	Pathogenic	0.985
LRP5	O75197-1.2	P1026Q	Pathogenic	0.968
LRP5	O75197-1.2	P1026R	Pathogenic	0.977
LRP5	O75197-1.2	P1026S	Pathogenic	0.973
LRP5	O75197-1.2	P1026T	Pathogenic	0.979
LRP5	O75197-1.2	P1026V	Pathogenic	0.993
LRP5	O75197-1.2	P1026W	Pathogenic	0.998
LRP5	O75197-1.2	P1026Y	Pathogenic	0.998
LRP5	O75197-1.2	H1027A	Pathogenic	0.915
LRP5	O75197-1.2	H1027C	Pathogenic	0.948
LRP5	O75197-1.2	H1027D	Pathogenic	0.657
LRP5	O75197-1.2	H1027E	Neutral	0.421
LRP5	O75197-1.2	H1027F	Neutral	0.497
LRP5	O75197-1.2	H1027G	Pathogenic	0.915
LRP5	O75197-1.2	H1027I	Pathogenic	0.902
LRP5	O75197-1.2	H1027K	Pathogenic	0.615
LRP5	O75197-1.2	H1027L	Pathogenic	0.91
LRP5	O75197-1.2	H1027M	Pathogenic	0.834
LRP5	O75197-1.2	H1027N	Neutral	0.195
LRP5	O75197-1.2	H1027P	Pathogenic	0.885
LRP5	O75197-1.2	H1027Q	Pathogenic	0.516
LRP5	O75197-1.2	H1027R	Neutral	0.337
LRP5	O75197-1.2	H1027S	Pathogenic	0.782
LRP5	O75197-1.2	H1027T	Pathogenic	0.921
LRP5	O75197-1.2	H1027V	Pathogenic	0.939
LRP5	O75197-1.2	H1027W	Pathogenic	0.656
LRP5	O75197-1.2	H1027Y	Neutral	0.068
LRP5	O75197-1.2	D1028A	Pathogenic	0.997
LRP5	O75197-1.2	D1028C	Pathogenic	0.998
LRP5	O75197-1.2	D1028E	Pathogenic	0.907
LRP5	O75197-1.2	D1028F	Pathogenic	0.996
LRP5	O75197-1.2	D1028G	Pathogenic	0.993
LRP5	O75197-1.2	D1028H	Pathogenic	0.993
LRP5	O75197-1.2	D1028I	Pathogenic	0.996
LRP5	O75197-1.2	D1028K	Pathogenic	0.996
LRP5	O75197-1.2	D1028L	Pathogenic	0.999
LRP5	O75197-1.2	D1028M	Pathogenic	0.998
LRP5	O75197-1.2	D1028N	Pathogenic	0.967
LRP5	O75197-1.2	D1028P	Pathogenic	0.988
LRP5	O75197-1.2	D1028Q	Pathogenic	0.984
LRP5	O75197-1.2	D1028R	Pathogenic	0.999
LRP5	O75197-1.2	D1028S	Pathogenic	0.981
LRP5	O75197-1.2	D1028T	Pathogenic	0.992
LRP5	O75197-1.2	D1028V	Pathogenic	0.998
LRP5	O75197-1.2	D1028W	Pathogenic	0.998
LRP5	O75197-1.2	D1028Y	Pathogenic	0.998
LRP5	O75197-1.2	L1029A	Pathogenic	0.957
LRP5	O75197-1.2	L1029C	Pathogenic	0.977
LRP5	O75197-1.2	L1029D	Pathogenic	0.996
LRP5	O75197-1.2	L1029E	Pathogenic	0.99
LRP5	O75197-1.2	L1029F	Pathogenic	0.962
LRP5	O75197-1.2	L1029G	Pathogenic	0.998
LRP5	O75197-1.2	L1029H	Pathogenic	0.995
LRP5	O75197-1.2	L1029I	Pathogenic	0.734
LRP5	O75197-1.2	L1029K	Pathogenic	0.958
LRP5	O75197-1.2	L1029M	Pathogenic	0.665
LRP5	O75197-1.2	L1029N	Pathogenic	0.99
LRP5	O75197-1.2	L1029P	Pathogenic	0.997
LRP5	O75197-1.2	L1029Q	Pathogenic	0.979
LRP5	O75197-1.2	L1029R	Pathogenic	0.957
LRP5	O75197-1.2	L1029S	Pathogenic	0.981
LRP5	O75197-1.2	L1029T	Pathogenic	0.957
LRP5	O75197-1.2	L1029V	Pathogenic	0.853
LRP5	O75197-1.2	L1029W	Pathogenic	0.993
LRP5	O75197-1.2	L1029Y	Pathogenic	0.977
LRP5	O75197-1.2	S1030A	Pathogenic	0.734
LRP5	O75197-1.2	S1030C	Pathogenic	0.932
LRP5	O75197-1.2	S1030D	Pathogenic	0.853
LRP5	O75197-1.2	S1030E	Pathogenic	0.864
LRP5	O75197-1.2	S1030F	Pathogenic	0.95
LRP5	O75197-1.2	S1030G	Pathogenic	0.915
LRP5	O75197-1.2	S1030H	Pathogenic	0.966
LRP5	O75197-1.2	S1030I	Pathogenic	0.95
LRP5	O75197-1.2	S1030K	Pathogenic	0.817
LRP5	O75197-1.2	S1030L	Pathogenic	0.954
LRP5	O75197-1.2	S1030M	Pathogenic	0.912
LRP5	O75197-1.2	S1030N	Pathogenic	0.688
LRP5	O75197-1.2	S1030P	Pathogenic	0.946
LRP5	O75197-1.2	S1030Q	Pathogenic	0.902
LRP5	O75197-1.2	S1030R	Pathogenic	0.929
LRP5	O75197-1.2	S1030T	Pathogenic	0.738
LRP5	O75197-1.2	S1030V	Pathogenic	0.971
LRP5	O75197-1.2	S1030W	Pathogenic	0.973
LRP5	O75197-1.2	S1030Y	Pathogenic	0.975
LRP5	O75197-1.2	I1031A	Pathogenic	0.778
LRP5	O75197-1.2	I1031C	Pathogenic	0.868
LRP5	O75197-1.2	I1031D	Pathogenic	0.928
LRP5	O75197-1.2	I1031E	Pathogenic	0.937
LRP5	O75197-1.2	I1031F	Pathogenic	0.823
LRP5	O75197-1.2	I1031G	Pathogenic	0.986
LRP5	O75197-1.2	I1031H	Pathogenic	0.968
LRP5	O75197-1.2	I1031K	Pathogenic	0.916
LRP5	O75197-1.2	I1031L	Neutral	0.321
LRP5	O75197-1.2	I1031M	Neutral	0.486
LRP5	O75197-1.2	I1031N	Pathogenic	0.938
LRP5	O75197-1.2	I1031P	Pathogenic	0.98
LRP5	O75197-1.2	I1031Q	Pathogenic	0.956
LRP5	O75197-1.2	I1031R	Pathogenic	0.913
LRP5	O75197-1.2	I1031S	Pathogenic	0.888
LRP5	O75197-1.2	I1031T	Pathogenic	0.777
LRP5	O75197-1.2	I1031V	Neutral	0.089
LRP5	O75197-1.2	I1031W	Pathogenic	0.988
LRP5	O75197-1.2	I1031Y	Pathogenic	0.87
LRP5	O75197-1.2	D1032A	Pathogenic	0.996
LRP5	O75197-1.2	D1032C	Pathogenic	0.998
LRP5	O75197-1.2	D1032E	Pathogenic	0.866
LRP5	O75197-1.2	D1032F	Pathogenic	0.995
LRP5	O75197-1.2	D1032G	Pathogenic	0.99
LRP5	O75197-1.2	D1032H	Pathogenic	0.989
LRP5	O75197-1.2	D1032I	Pathogenic	0.995
LRP5	O75197-1.2	D1032K	Pathogenic	0.994
LRP5	O75197-1.2	D1032L	Pathogenic	0.998
LRP5	O75197-1.2	D1032M	Pathogenic	0.997
LRP5	O75197-1.2	D1032N	Pathogenic	0.951
LRP5	O75197-1.2	D1032P	Pathogenic	0.982
LRP5	O75197-1.2	D1032Q	Pathogenic	0.976
LRP5	O75197-1.2	D1032R	Pathogenic	0.998
LRP5	O75197-1.2	D1032S	Pathogenic	0.972
LRP5	O75197-1.2	D1032T	Pathogenic	0.988
LRP5	O75197-1.2	D1032V	Pathogenic	0.997
LRP5	O75197-1.2	D1032W	Pathogenic	0.997
LRP5	O75197-1.2	D1032Y	Pathogenic	0.997
LRP5	O75197-1.2	I1033A	Neutral	0.32
LRP5	O75197-1.2	I1033C	Neutral	0.47
LRP5	O75197-1.2	I1033D	Pathogenic	0.633
LRP5	O75197-1.2	I1033E	Pathogenic	0.666
LRP5	O75197-1.2	I1033F	Neutral	0.385
LRP5	O75197-1.2	I1033G	Pathogenic	0.907
LRP5	O75197-1.2	I1033H	Pathogenic	0.801
LRP5	O75197-1.2	I1033K	Pathogenic	0.595
LRP5	O75197-1.2	I1033L	Neutral	0.06
LRP5	O75197-1.2	I1033M	Neutral	0.113
LRP5	O75197-1.2	I1033N	Pathogenic	0.669
LRP5	O75197-1.2	I1033P	Pathogenic	0.867
LRP5	O75197-1.2	I1033Q	Pathogenic	0.745
LRP5	O75197-1.2	I1033R	Pathogenic	0.586
LRP5	O75197-1.2	I1033S	Pathogenic	0.515
LRP5	O75197-1.2	I1033T	Neutral	0.319
LRP5	O75197-1.2	I1033V	Neutral	0.013
LRP5	O75197-1.2	I1033W	Pathogenic	0.92
LRP5	O75197-1.2	I1033Y	Neutral	0.473
LRP5	O75197-1.2	Y1034A	Pathogenic	0.992
LRP5	O75197-1.2	Y1034C	Pathogenic	0.996
LRP5	O75197-1.2	Y1034D	Pathogenic	0.994
LRP5	O75197-1.2	Y1034E	Pathogenic	0.983
LRP5	O75197-1.2	Y1034F	Neutral	0.319
LRP5	O75197-1.2	Y1034G	Pathogenic	0.997
LRP5	O75197-1.2	Y1034H	Pathogenic	0.581
LRP5	O75197-1.2	Y1034I	Pathogenic	0.975
LRP5	O75197-1.2	Y1034K	Pathogenic	0.978
LRP5	O75197-1.2	Y1034L	Pathogenic	0.977
LRP5	O75197-1.2	Y1034M	Pathogenic	0.985
LRP5	O75197-1.2	Y1034N	Pathogenic	0.983
LRP5	O75197-1.2	Y1034P	Pathogenic	0.998
LRP5	O75197-1.2	Y1034Q	Pathogenic	0.966
LRP5	O75197-1.2	Y1034R	Pathogenic	0.978
LRP5	O75197-1.2	Y1034S	Pathogenic	0.99
LRP5	O75197-1.2	Y1034T	Pathogenic	0.992
LRP5	O75197-1.2	Y1034V	Pathogenic	0.985
LRP5	O75197-1.2	Y1034W	Neutral	0.479
LRP5	O75197-1.2	S1035A	Pathogenic	0.746
LRP5	O75197-1.2	S1035C	Pathogenic	0.936
LRP5	O75197-1.2	S1035D	Pathogenic	0.861
LRP5	O75197-1.2	S1035E	Pathogenic	0.871
LRP5	O75197-1.2	S1035F	Pathogenic	0.953
LRP5	O75197-1.2	S1035G	Pathogenic	0.919
LRP5	O75197-1.2	S1035H	Pathogenic	0.968
LRP5	O75197-1.2	S1035I	Pathogenic	0.953
LRP5	O75197-1.2	S1035K	Pathogenic	0.826
LRP5	O75197-1.2	S1035L	Pathogenic	0.957
LRP5	O75197-1.2	S1035M	Pathogenic	0.917
LRP5	O75197-1.2	S1035N	Pathogenic	0.701
LRP5	O75197-1.2	S1035P	Pathogenic	0.949
LRP5	O75197-1.2	S1035Q	Pathogenic	0.907
LRP5	O75197-1.2	S1035R	Pathogenic	0.933
LRP5	O75197-1.2	S1035T	Pathogenic	0.75
LRP5	O75197-1.2	S1035V	Pathogenic	0.972
LRP5	O75197-1.2	S1035W	Pathogenic	0.975
LRP5	O75197-1.2	S1035Y	Pathogenic	0.977
LRP5	O75197-1.2	R1036A	Pathogenic	0.947
LRP5	O75197-1.2	R1036C	Pathogenic	0.989
LRP5	O75197-1.2	R1036D	Pathogenic	0.993
LRP5	O75197-1.2	R1036E	Pathogenic	0.936
LRP5	O75197-1.2	R1036F	Pathogenic	0.98
LRP5	O75197-1.2	R1036G	Pathogenic	0.986
LRP5	O75197-1.2	R1036H	Pathogenic	0.882
LRP5	O75197-1.2	R1036I	Pathogenic	0.979
LRP5	O75197-1.2	R1036K	Pathogenic	0.694
LRP5	O75197-1.2	R1036L	Pathogenic	0.945
LRP5	O75197-1.2	R1036M	Pathogenic	0.896
LRP5	O75197-1.2	R1036N	Pathogenic	0.933
LRP5	O75197-1.2	R1036P	Pathogenic	0.975
LRP5	O75197-1.2	R1036Q	Pathogenic	0.77
LRP5	O75197-1.2	R1036S	Pathogenic	0.961
LRP5	O75197-1.2	R1036T	Pathogenic	0.951
LRP5	O75197-1.2	R1036V	Pathogenic	0.987
LRP5	O75197-1.2	R1036W	Pathogenic	0.97
LRP5	O75197-1.2	R1036Y	Pathogenic	0.972
LRP5	O75197-1.2	T1037A	Neutral	0.03
LRP5	O75197-1.2	T1037C	Neutral	0.051
LRP5	O75197-1.2	T1037D	Neutral	0.04
LRP5	O75197-1.2	T1037E	Neutral	0.043
LRP5	O75197-1.2	T1037F	Neutral	0.07
LRP5	O75197-1.2	T1037G	Neutral	0.189
LRP5	O75197-1.2	T1037H	Neutral	0.213
LRP5	O75197-1.2	T1037I	Neutral	0.024
LRP5	O75197-1.2	T1037K	Neutral	0.031
LRP5	O75197-1.2	T1037L	Neutral	0.026
LRP5	O75197-1.2	T1037M	Neutral	0.04
LRP5	O75197-1.2	T1037N	Neutral	0.015
LRP5	O75197-1.2	T1037P	Neutral	0.064
LRP5	O75197-1.2	T1037Q	Neutral	0.061
LRP5	O75197-1.2	T1037R	Neutral	0.03
LRP5	O75197-1.2	T1037S	Neutral	0.008
LRP5	O75197-1.2	T1037V	Neutral	0.014
LRP5	O75197-1.2	T1037W	Neutral	0.045
LRP5	O75197-1.2	T1037Y	Neutral	0.135
LRP5	O75197-1.2	L1038A	Neutral	0.238
LRP5	O75197-1.2	L1038C	Neutral	0.37
LRP5	O75197-1.2	L1038D	Pathogenic	0.777
LRP5	O75197-1.2	L1038E	Pathogenic	0.57
LRP5	O75197-1.2	L1038F	Neutral	0.262
LRP5	O75197-1.2	L1038G	Pathogenic	0.866
LRP5	O75197-1.2	L1038H	Pathogenic	0.728
LRP5	O75197-1.2	L1038I	Neutral	0.037
LRP5	O75197-1.2	L1038K	Neutral	0.242
LRP5	O75197-1.2	L1038M	Neutral	0.027
LRP5	O75197-1.2	L1038N	Pathogenic	0.573
LRP5	O75197-1.2	L1038P	Pathogenic	0.812
LRP5	O75197-1.2	L1038Q	Neutral	0.389
LRP5	O75197-1.2	L1038R	Neutral	0.236
LRP5	O75197-1.2	L1038S	Neutral	0.413
LRP5	O75197-1.2	L1038T	Neutral	0.237
LRP5	O75197-1.2	L1038V	Neutral	0.075
LRP5	O75197-1.2	L1038W	Pathogenic	0.675
LRP5	O75197-1.2	L1038Y	Neutral	0.373
LRP5	O75197-1.2	F1039A	Pathogenic	0.9
LRP5	O75197-1.2	F1039C	Pathogenic	0.944
LRP5	O75197-1.2	F1039D	Pathogenic	0.916
LRP5	O75197-1.2	F1039E	Pathogenic	0.926
LRP5	O75197-1.2	F1039G	Pathogenic	0.953
LRP5	O75197-1.2	F1039H	Pathogenic	0.733
LRP5	O75197-1.2	F1039I	Pathogenic	0.798
LRP5	O75197-1.2	F1039K	Pathogenic	0.905
LRP5	O75197-1.2	F1039L	Pathogenic	0.787
LRP5	O75197-1.2	F1039M	Pathogenic	0.709
LRP5	O75197-1.2	F1039N	Pathogenic	0.927
LRP5	O75197-1.2	F1039P	Pathogenic	0.992
LRP5	O75197-1.2	F1039Q	Pathogenic	0.948
LRP5	O75197-1.2	F1039R	Pathogenic	0.902
LRP5	O75197-1.2	F1039S	Pathogenic	0.87
LRP5	O75197-1.2	F1039T	Pathogenic	0.9
LRP5	O75197-1.2	F1039V	Pathogenic	0.876
LRP5	O75197-1.2	F1039W	Neutral	0.459
LRP5	O75197-1.2	F1039Y	Neutral	0.064
LRP5	O75197-1.2	W1040A	Pathogenic	1.0
LRP5	O75197-1.2	W1040C	Pathogenic	0.999
LRP5	O75197-1.2	W1040D	Pathogenic	1.0
LRP5	O75197-1.2	W1040E	Pathogenic	0.999
LRP5	O75197-1.2	W1040F	Pathogenic	0.991
LRP5	O75197-1.2	W1040G	Pathogenic	0.998
LRP5	O75197-1.2	W1040H	Pathogenic	0.999
LRP5	O75197-1.2	W1040I	Pathogenic	1.0
LRP5	O75197-1.2	W1040K	Pathogenic	0.999
LRP5	O75197-1.2	W1040L	Pathogenic	1.0
LRP5	O75197-1.2	W1040M	Pathogenic	0.998
LRP5	O75197-1.2	W1040N	Pathogenic	1.0
LRP5	O75197-1.2	W1040P	Pathogenic	1.0
LRP5	O75197-1.2	W1040Q	Pathogenic	0.998
LRP5	O75197-1.2	W1040R	Pathogenic	0.999
LRP5	O75197-1.2	W1040S	Pathogenic	0.999
LRP5	O75197-1.2	W1040T	Pathogenic	0.999
LRP5	O75197-1.2	W1040V	Pathogenic	1.0
LRP5	O75197-1.2	W1040Y	Pathogenic	0.945
LRP5	O75197-1.2	T1041A	Pathogenic	0.977
LRP5	O75197-1.2	T1041C	Pathogenic	0.986
LRP5	O75197-1.2	T1041D	Pathogenic	0.982
LRP5	O75197-1.2	T1041E	Pathogenic	0.984
LRP5	O75197-1.2	T1041F	Pathogenic	0.99
LRP5	O75197-1.2	T1041G	Pathogenic	0.997
LRP5	O75197-1.2	T1041H	Pathogenic	0.997
LRP5	O75197-1.2	T1041I	Pathogenic	0.971
LRP5	O75197-1.2	T1041K	Pathogenic	0.977
LRP5	O75197-1.2	T1041L	Pathogenic	0.973
LRP5	O75197-1.2	T1041M	Pathogenic	0.982
LRP5	O75197-1.2	T1041N	Pathogenic	0.955
LRP5	O75197-1.2	T1041P	Pathogenic	0.989
LRP5	O75197-1.2	T1041Q	Pathogenic	0.989
LRP5	O75197-1.2	T1041R	Pathogenic	0.976
LRP5	O75197-1.2	T1041S	Pathogenic	0.919
LRP5	O75197-1.2	T1041V	Pathogenic	0.95
LRP5	O75197-1.2	T1041W	Pathogenic	0.985
LRP5	O75197-1.2	T1041Y	Pathogenic	0.995
LRP5	O75197-1.2	C1042A	Pathogenic	0.966
LRP5	O75197-1.2	C1042D	Pathogenic	0.997
LRP5	O75197-1.2	C1042E	Pathogenic	0.999
LRP5	O75197-1.2	C1042F	Pathogenic	0.996
LRP5	O75197-1.2	C1042G	Pathogenic	0.998
LRP5	O75197-1.2	C1042H	Pathogenic	0.999
LRP5	O75197-1.2	C1042I	Pathogenic	0.987
LRP5	O75197-1.2	C1042K	Pathogenic	0.996
LRP5	O75197-1.2	C1042L	Pathogenic	0.988
LRP5	O75197-1.2	C1042M	Pathogenic	0.992
LRP5	O75197-1.2	C1042N	Pathogenic	0.997
LRP5	O75197-1.2	C1042P	Pathogenic	0.999
LRP5	O75197-1.2	C1042Q	Pathogenic	0.998
LRP5	O75197-1.2	C1042R	Pathogenic	0.996
LRP5	O75197-1.2	C1042S	Pathogenic	0.985
LRP5	O75197-1.2	C1042T	Pathogenic	0.988
LRP5	O75197-1.2	C1042V	Pathogenic	0.992
LRP5	O75197-1.2	C1042W	Pathogenic	0.993
LRP5	O75197-1.2	C1042Y	Pathogenic	0.998
LRP5	O75197-1.2	E1043A	Pathogenic	0.898
LRP5	O75197-1.2	E1043C	Pathogenic	0.993
LRP5	O75197-1.2	E1043D	Neutral	0.403
LRP5	O75197-1.2	E1043F	Pathogenic	0.957
LRP5	O75197-1.2	E1043G	Pathogenic	0.972
LRP5	O75197-1.2	E1043H	Pathogenic	0.782
LRP5	O75197-1.2	E1043I	Pathogenic	0.957
LRP5	O75197-1.2	E1043K	Pathogenic	0.625
LRP5	O75197-1.2	E1043L	Pathogenic	0.961
LRP5	O75197-1.2	E1043M	Pathogenic	0.925
LRP5	O75197-1.2	E1043N	Pathogenic	0.873
LRP5	O75197-1.2	E1043P	Pathogenic	0.864
LRP5	O75197-1.2	E1043Q	Neutral	0.348
LRP5	O75197-1.2	E1043R	Pathogenic	0.83
LRP5	O75197-1.2	E1043S	Pathogenic	0.8
LRP5	O75197-1.2	E1043T	Pathogenic	0.906
LRP5	O75197-1.2	E1043V	Pathogenic	0.927
LRP5	O75197-1.2	E1043W	Pathogenic	0.934
LRP5	O75197-1.2	E1043Y	Pathogenic	0.938
LRP5	O75197-1.2	A1044C	Neutral	0.18
LRP5	O75197-1.2	A1044D	Pathogenic	0.584
LRP5	O75197-1.2	A1044E	Neutral	0.335
LRP5	O75197-1.2	A1044F	Neutral	0.477
LRP5	O75197-1.2	A1044G	Neutral	0.233
LRP5	O75197-1.2	A1044H	Pathogenic	0.75
LRP5	O75197-1.2	A1044I	Neutral	0.231
LRP5	O75197-1.2	A1044K	Neutral	0.261
LRP5	O75197-1.2	A1044L	Neutral	0.248
LRP5	O75197-1.2	A1044M	Neutral	0.334
LRP5	O75197-1.2	A1044N	Pathogenic	0.618
LRP5	O75197-1.2	A1044P	Neutral	0.456
LRP5	O75197-1.2	A1044Q	Neutral	0.421
LRP5	O75197-1.2	A1044R	Neutral	0.254
LRP5	O75197-1.2	A1044S	Neutral	0.09
LRP5	O75197-1.2	A1044T	Neutral	0.274
LRP5	O75197-1.2	A1044V	Neutral	0.147
LRP5	O75197-1.2	A1044W	Pathogenic	0.637
LRP5	O75197-1.2	A1044Y	Pathogenic	0.654
LRP5	O75197-1.2	T1045A	Pathogenic	0.895
LRP5	O75197-1.2	T1045C	Pathogenic	0.936
LRP5	O75197-1.2	T1045D	Pathogenic	0.918
LRP5	O75197-1.2	T1045E	Pathogenic	0.925
LRP5	O75197-1.2	T1045F	Pathogenic	0.953
LRP5	O75197-1.2	T1045G	Pathogenic	0.984
LRP5	O75197-1.2	T1045H	Pathogenic	0.987
LRP5	O75197-1.2	T1045I	Pathogenic	0.871
LRP5	O75197-1.2	T1045K	Pathogenic	0.896
LRP5	O75197-1.2	T1045L	Pathogenic	0.881
LRP5	O75197-1.2	T1045M	Pathogenic	0.918
LRP5	O75197-1.2	T1045N	Pathogenic	0.811
LRP5	O75197-1.2	T1045P	Pathogenic	0.949
LRP5	O75197-1.2	T1045Q	Pathogenic	0.947
LRP5	O75197-1.2	T1045R	Pathogenic	0.893
LRP5	O75197-1.2	T1045S	Pathogenic	0.694
LRP5	O75197-1.2	T1045V	Pathogenic	0.794
LRP5	O75197-1.2	T1045W	Pathogenic	0.928
LRP5	O75197-1.2	T1045Y	Pathogenic	0.977
LRP5	O75197-1.2	N1046A	Pathogenic	0.996
LRP5	O75197-1.2	N1046C	Pathogenic	0.997
LRP5	O75197-1.2	N1046D	Pathogenic	0.941
LRP5	O75197-1.2	N1046E	Pathogenic	0.982
LRP5	O75197-1.2	N1046F	Pathogenic	0.994
LRP5	O75197-1.2	N1046G	Pathogenic	0.969
LRP5	O75197-1.2	N1046H	Pathogenic	0.904
LRP5	O75197-1.2	N1046I	Pathogenic	0.994
LRP5	O75197-1.2	N1046K	Pathogenic	0.974
LRP5	O75197-1.2	N1046L	Pathogenic	0.995
LRP5	O75197-1.2	N1046M	Pathogenic	0.99
LRP5	O75197-1.2	N1046P	Pathogenic	0.994
LRP5	O75197-1.2	N1046Q	Pathogenic	0.975
LRP5	O75197-1.2	N1046R	Pathogenic	0.974
LRP5	O75197-1.2	N1046S	Pathogenic	0.916
LRP5	O75197-1.2	N1046T	Pathogenic	0.964
LRP5	O75197-1.2	N1046V	Pathogenic	0.997
LRP5	O75197-1.2	N1046W	Pathogenic	0.997
LRP5	O75197-1.2	N1046Y	Pathogenic	0.992
LRP5	O75197-1.2	T1047A	Neutral	0.137
LRP5	O75197-1.2	T1047C	Neutral	0.215
LRP5	O75197-1.2	T1047D	Neutral	0.174
LRP5	O75197-1.2	T1047E	Neutral	0.188
LRP5	O75197-1.2	T1047F	Neutral	0.276
LRP5	O75197-1.2	T1047G	Pathogenic	0.543
LRP5	O75197-1.2	T1047H	Pathogenic	0.58
LRP5	O75197-1.2	T1047I	Neutral	0.112
LRP5	O75197-1.2	T1047K	Neutral	0.14
LRP5	O75197-1.2	T1047L	Neutral	0.121
LRP5	O75197-1.2	T1047M	Neutral	0.174
LRP5	O75197-1.2	T1047N	Neutral	0.074
LRP5	O75197-1.2	T1047P	Neutral	0.258
LRP5	O75197-1.2	T1047Q	Neutral	0.25
LRP5	O75197-1.2	T1047R	Neutral	0.135
LRP5	O75197-1.2	T1047S	Neutral	0.041
LRP5	O75197-1.2	T1047V	Neutral	0.067
LRP5	O75197-1.2	T1047W	Neutral	0.195
LRP5	O75197-1.2	T1047Y	Neutral	0.442
LRP5	O75197-1.2	I1048A	Pathogenic	0.952
LRP5	O75197-1.2	I1048C	Pathogenic	0.974
LRP5	O75197-1.2	I1048D	Pathogenic	0.986
LRP5	O75197-1.2	I1048E	Pathogenic	0.988
LRP5	O75197-1.2	I1048F	Pathogenic	0.963
LRP5	O75197-1.2	I1048G	Pathogenic	0.998
LRP5	O75197-1.2	I1048H	Pathogenic	0.994
LRP5	O75197-1.2	I1048K	Pathogenic	0.984
LRP5	O75197-1.2	I1048L	Pathogenic	0.728
LRP5	O75197-1.2	I1048M	Pathogenic	0.843
LRP5	O75197-1.2	I1048N	Pathogenic	0.988
LRP5	O75197-1.2	I1048P	Pathogenic	0.996
LRP5	O75197-1.2	I1048Q	Pathogenic	0.992
LRP5	O75197-1.2	I1048R	Pathogenic	0.984
LRP5	O75197-1.2	I1048S	Pathogenic	0.978
LRP5	O75197-1.2	I1048T	Pathogenic	0.952
LRP5	O75197-1.2	I1048V	Neutral	0.357
LRP5	O75197-1.2	I1048W	Pathogenic	0.998
LRP5	O75197-1.2	I1048Y	Pathogenic	0.974
LRP5	O75197-1.2	N1049A	Pathogenic	0.997
LRP5	O75197-1.2	N1049C	Pathogenic	0.998
LRP5	O75197-1.2	N1049D	Pathogenic	0.962
LRP5	O75197-1.2	N1049E	Pathogenic	0.988
LRP5	O75197-1.2	N1049F	Pathogenic	0.996
LRP5	O75197-1.2	N1049G	Pathogenic	0.98
LRP5	O75197-1.2	N1049H	Pathogenic	0.937
LRP5	O75197-1.2	N1049I	Pathogenic	0.996
LRP5	O75197-1.2	N1049K	Pathogenic	0.984
LRP5	O75197-1.2	N1049L	Pathogenic	0.997
LRP5	O75197-1.2	N1049M	Pathogenic	0.994
LRP5	O75197-1.2	N1049P	Pathogenic	0.996
LRP5	O75197-1.2	N1049Q	Pathogenic	0.984
LRP5	O75197-1.2	N1049R	Pathogenic	0.983
LRP5	O75197-1.2	N1049S	Pathogenic	0.945
LRP5	O75197-1.2	N1049T	Pathogenic	0.977
LRP5	O75197-1.2	N1049V	Pathogenic	0.998
LRP5	O75197-1.2	N1049W	Pathogenic	0.998
LRP5	O75197-1.2	N1049Y	Pathogenic	0.995
LRP5	O75197-1.2	V1050A	Pathogenic	0.885
LRP5	O75197-1.2	V1050C	Pathogenic	0.978
LRP5	O75197-1.2	V1050D	Pathogenic	0.989
LRP5	O75197-1.2	V1050E	Pathogenic	0.97
LRP5	O75197-1.2	V1050F	Pathogenic	0.97
LRP5	O75197-1.2	V1050G	Pathogenic	0.994
LRP5	O75197-1.2	V1050H	Pathogenic	0.995
LRP5	O75197-1.2	V1050I	Neutral	0.274
LRP5	O75197-1.2	V1050K	Pathogenic	0.958
LRP5	O75197-1.2	V1050L	Pathogenic	0.793
LRP5	O75197-1.2	V1050M	Pathogenic	0.853
LRP5	O75197-1.2	V1050N	Pathogenic	0.99
LRP5	O75197-1.2	V1050P	Pathogenic	0.991
LRP5	O75197-1.2	V1050Q	Pathogenic	0.979
LRP5	O75197-1.2	V1050R	Pathogenic	0.985
LRP5	O75197-1.2	V1050S	Pathogenic	0.981
LRP5	O75197-1.2	V1050T	Pathogenic	0.885
LRP5	O75197-1.2	V1050W	Pathogenic	0.995
LRP5	O75197-1.2	V1050Y	Pathogenic	0.977
LRP5	O75197-1.2	H1051A	Pathogenic	0.811
LRP5	O75197-1.2	H1051C	Pathogenic	0.88
LRP5	O75197-1.2	H1051D	Neutral	0.434
LRP5	O75197-1.2	H1051E	Neutral	0.226
LRP5	O75197-1.2	H1051F	Neutral	0.284
LRP5	O75197-1.2	H1051G	Pathogenic	0.812
LRP5	O75197-1.2	H1051I	Pathogenic	0.786
LRP5	O75197-1.2	H1051K	Neutral	0.39
LRP5	O75197-1.2	H1051L	Pathogenic	0.801
LRP5	O75197-1.2	H1051M	Pathogenic	0.669
LRP5	O75197-1.2	H1051N	Neutral	0.088
LRP5	O75197-1.2	H1051P	Pathogenic	0.755
LRP5	O75197-1.2	H1051Q	Neutral	0.299
LRP5	O75197-1.2	H1051R	Neutral	0.169
LRP5	O75197-1.2	H1051S	Pathogenic	0.589
LRP5	O75197-1.2	H1051T	Pathogenic	0.824
LRP5	O75197-1.2	H1051V	Pathogenic	0.86
LRP5	O75197-1.2	H1051W	Neutral	0.432
LRP5	O75197-1.2	H1051Y	Neutral	0.028
LRP5	O75197-1.2	R1052A	Pathogenic	0.954
LRP5	O75197-1.2	R1052C	Pathogenic	0.991
LRP5	O75197-1.2	R1052D	Pathogenic	0.994
LRP5	O75197-1.2	R1052E	Pathogenic	0.945
LRP5	O75197-1.2	R1052F	Pathogenic	0.983
LRP5	O75197-1.2	R1052G	Pathogenic	0.988
LRP5	O75197-1.2	R1052H	Pathogenic	0.897
LRP5	O75197-1.2	R1052I	Pathogenic	0.982
LRP5	O75197-1.2	R1052K	Pathogenic	0.725
LRP5	O75197-1.2	R1052L	Pathogenic	0.952
LRP5	O75197-1.2	R1052M	Pathogenic	0.909
LRP5	O75197-1.2	R1052N	Pathogenic	0.942
LRP5	O75197-1.2	R1052P	Pathogenic	0.978
LRP5	O75197-1.2	R1052Q	Pathogenic	0.795
LRP5	O75197-1.2	R1052S	Pathogenic	0.966
LRP5	O75197-1.2	R1052T	Pathogenic	0.958
LRP5	O75197-1.2	R1052V	Pathogenic	0.989
LRP5	O75197-1.2	R1052W	Pathogenic	0.974
LRP5	O75197-1.2	R1052Y	Pathogenic	0.975
LRP5	O75197-1.2	L1053A	Pathogenic	0.765
LRP5	O75197-1.2	L1053C	Pathogenic	0.86
LRP5	O75197-1.2	L1053D	Pathogenic	0.973
LRP5	O75197-1.2	L1053E	Pathogenic	0.933
LRP5	O75197-1.2	L1053F	Pathogenic	0.788
LRP5	O75197-1.2	L1053G	Pathogenic	0.985
LRP5	O75197-1.2	L1053H	Pathogenic	0.966
LRP5	O75197-1.2	L1053I	Neutral	0.287
LRP5	O75197-1.2	L1053K	Pathogenic	0.77
LRP5	O75197-1.2	L1053M	Neutral	0.225
LRP5	O75197-1.2	L1053N	Pathogenic	0.933
LRP5	O75197-1.2	L1053P	Pathogenic	0.978
LRP5	O75197-1.2	L1053Q	Pathogenic	0.87
LRP5	O75197-1.2	L1053R	Pathogenic	0.764
LRP5	O75197-1.2	L1053S	Pathogenic	0.88
LRP5	O75197-1.2	L1053T	Pathogenic	0.765
LRP5	O75197-1.2	L1053V	Neutral	0.458
LRP5	O75197-1.2	L1053W	Pathogenic	0.956
LRP5	O75197-1.2	L1053Y	Pathogenic	0.862
LRP5	O75197-1.2	S1054A	Neutral	0.023
LRP5	O75197-1.2	S1054C	Neutral	0.106
LRP5	O75197-1.2	S1054D	Neutral	0.047
LRP5	O75197-1.2	S1054E	Neutral	0.052
LRP5	O75197-1.2	S1054F	Neutral	0.139
LRP5	O75197-1.2	S1054G	Neutral	0.084
LRP5	O75197-1.2	S1054H	Neutral	0.193
LRP5	O75197-1.2	S1054I	Neutral	0.139
LRP5	O75197-1.2	S1054K	Neutral	0.037
LRP5	O75197-1.2	S1054L	Neutral	0.151
LRP5	O75197-1.2	S1054M	Neutral	0.082
LRP5	O75197-1.2	S1054N	Neutral	0.018
LRP5	O75197-1.2	S1054P	Neutral	0.129
LRP5	O75197-1.2	S1054Q	Neutral	0.073
LRP5	O75197-1.2	S1054R	Neutral	0.101
LRP5	O75197-1.2	S1054T	Neutral	0.024
LRP5	O75197-1.2	S1054V	Neutral	0.22
LRP5	O75197-1.2	S1054W	Neutral	0.237
LRP5	O75197-1.2	S1054Y	Neutral	0.251
LRP5	O75197-1.2	G1055A	Pathogenic	0.911
LRP5	O75197-1.2	G1055C	Pathogenic	0.993
LRP5	O75197-1.2	G1055D	Pathogenic	0.952
LRP5	O75197-1.2	G1055E	Pathogenic	0.985
LRP5	O75197-1.2	G1055F	Pathogenic	0.986
LRP5	O75197-1.2	G1055H	Pathogenic	0.99
LRP5	O75197-1.2	G1055I	Pathogenic	0.995
LRP5	O75197-1.2	G1055K	Pathogenic	0.979
LRP5	O75197-1.2	G1055L	Pathogenic	0.996
LRP5	O75197-1.2	G1055M	Pathogenic	0.991
LRP5	O75197-1.2	G1055N	Pathogenic	0.882
LRP5	O75197-1.2	G1055P	Pathogenic	0.984
LRP5	O75197-1.2	G1055Q	Pathogenic	0.99
LRP5	O75197-1.2	G1055R	Pathogenic	0.978
LRP5	O75197-1.2	G1055S	Pathogenic	0.928
LRP5	O75197-1.2	G1055T	Pathogenic	0.99
LRP5	O75197-1.2	G1055V	Pathogenic	0.992
LRP5	O75197-1.2	G1055W	Pathogenic	0.934
LRP5	O75197-1.2	G1055Y	Pathogenic	0.993
LRP5	O75197-1.2	E1056A	Neutral	0.012
LRP5	O75197-1.2	E1056C	Neutral	0.167
LRP5	O75197-1.2	E1056D	Neutral	0.001
LRP5	O75197-1.2	E1056F	Neutral	0.031
LRP5	O75197-1.2	E1056G	Neutral	0.047
LRP5	O75197-1.2	E1056H	Neutral	0.005
LRP5	O75197-1.2	E1056I	Neutral	0.031
LRP5	O75197-1.2	E1056K	Neutral	0.002
LRP5	O75197-1.2	E1056L	Neutral	0.034
LRP5	O75197-1.2	E1056M	Neutral	0.017
LRP5	O75197-1.2	E1056N	Neutral	0.01
LRP5	O75197-1.2	E1056P	Neutral	0.009
LRP5	O75197-1.2	E1056Q	Neutral	0.001
LRP5	O75197-1.2	E1056R	Neutral	0.007
LRP5	O75197-1.2	E1056S	Neutral	0.006
LRP5	O75197-1.2	E1056T	Neutral	0.014
LRP5	O75197-1.2	E1056V	Neutral	0.018
LRP5	O75197-1.2	E1056W	Neutral	0.02
LRP5	O75197-1.2	E1056Y	Neutral	0.021
LRP5	O75197-1.2	A1057C	Neutral	0.021
LRP5	O75197-1.2	A1057D	Neutral	0.118
LRP5	O75197-1.2	A1057E	Neutral	0.046
LRP5	O75197-1.2	A1057F	Neutral	0.08
LRP5	O75197-1.2	A1057G	Neutral	0.028
LRP5	O75197-1.2	A1057H	Neutral	0.224
LRP5	O75197-1.2	A1057I	Neutral	0.028
LRP5	O75197-1.2	A1057K	Neutral	0.033
LRP5	O75197-1.2	A1057L	Neutral	0.031
LRP5	O75197-1.2	A1057M	Neutral	0.046
LRP5	O75197-1.2	A1057N	Neutral	0.134
LRP5	O75197-1.2	A1057P	Neutral	0.074
LRP5	O75197-1.2	A1057Q	Neutral	0.065
LRP5	O75197-1.2	A1057R	Neutral	0.032
LRP5	O75197-1.2	A1057S	Neutral	0.009
LRP5	O75197-1.2	A1057T	Neutral	0.035
LRP5	O75197-1.2	A1057V	Neutral	0.016
LRP5	O75197-1.2	A1057W	Neutral	0.144
LRP5	O75197-1.2	A1057Y	Neutral	0.153
LRP5	O75197-1.2	M1058A	Neutral	0.478
LRP5	O75197-1.2	M1058C	Pathogenic	0.633
LRP5	O75197-1.2	M1058D	Pathogenic	0.771
LRP5	O75197-1.2	M1058E	Pathogenic	0.561
LRP5	O75197-1.2	M1058F	Neutral	0.31
LRP5	O75197-1.2	M1058G	Pathogenic	0.862
LRP5	O75197-1.2	M1058H	Pathogenic	0.721
LRP5	O75197-1.2	M1058I	Neutral	0.129
LRP5	O75197-1.2	M1058K	Neutral	0.236
LRP5	O75197-1.2	M1058L	Neutral	0.051
LRP5	O75197-1.2	M1058N	Pathogenic	0.564
LRP5	O75197-1.2	M1058P	Pathogenic	0.807
LRP5	O75197-1.2	M1058Q	Neutral	0.169
LRP5	O75197-1.2	M1058R	Neutral	0.23
LRP5	O75197-1.2	M1058S	Neutral	0.405
LRP5	O75197-1.2	M1058T	Neutral	0.477
LRP5	O75197-1.2	M1058V	Neutral	0.192
LRP5	O75197-1.2	M1058W	Neutral	0.464
LRP5	O75197-1.2	M1058Y	Pathogenic	0.637
LRP5	O75197-1.2	G1059A	Pathogenic	0.989
LRP5	O75197-1.2	G1059C	Pathogenic	0.999
LRP5	O75197-1.2	G1059D	Pathogenic	0.994
LRP5	O75197-1.2	G1059E	Pathogenic	0.998
LRP5	O75197-1.2	G1059F	Pathogenic	0.998
LRP5	O75197-1.2	G1059H	Pathogenic	0.999
LRP5	O75197-1.2	G1059I	Pathogenic	0.999
LRP5	O75197-1.2	G1059K	Pathogenic	0.998
LRP5	O75197-1.2	G1059L	Pathogenic	1.0
LRP5	O75197-1.2	G1059M	Pathogenic	0.999
LRP5	O75197-1.2	G1059N	Pathogenic	0.985
LRP5	O75197-1.2	G1059P	Pathogenic	0.998
LRP5	O75197-1.2	G1059Q	Pathogenic	0.999
LRP5	O75197-1.2	G1059R	Pathogenic	0.997
LRP5	O75197-1.2	G1059S	Pathogenic	0.991
LRP5	O75197-1.2	G1059T	Pathogenic	0.999
LRP5	O75197-1.2	G1059V	Pathogenic	0.999
LRP5	O75197-1.2	G1059W	Pathogenic	0.992
LRP5	O75197-1.2	G1059Y	Pathogenic	0.999
LRP5	O75197-1.2	V1060A	Pathogenic	0.86
LRP5	O75197-1.2	V1060C	Pathogenic	0.972
LRP5	O75197-1.2	V1060D	Pathogenic	0.986
LRP5	O75197-1.2	V1060E	Pathogenic	0.963
LRP5	O75197-1.2	V1060F	Pathogenic	0.963
LRP5	O75197-1.2	V1060G	Pathogenic	0.992
LRP5	O75197-1.2	V1060H	Pathogenic	0.994
LRP5	O75197-1.2	V1060I	Neutral	0.231
LRP5	O75197-1.2	V1060K	Pathogenic	0.948
LRP5	O75197-1.2	V1060L	Pathogenic	0.753
LRP5	O75197-1.2	V1060M	Pathogenic	0.823
LRP5	O75197-1.2	V1060N	Pathogenic	0.988
LRP5	O75197-1.2	V1060P	Pathogenic	0.988
LRP5	O75197-1.2	V1060Q	Pathogenic	0.974
LRP5	O75197-1.2	V1060R	Pathogenic	0.982
LRP5	O75197-1.2	V1060S	Pathogenic	0.977
LRP5	O75197-1.2	V1060T	Pathogenic	0.86
LRP5	O75197-1.2	V1060W	Pathogenic	0.993
LRP5	O75197-1.2	V1060Y	Pathogenic	0.971
LRP5	O75197-1.2	V1061A	Pathogenic	0.959
LRP5	O75197-1.2	V1061C	Pathogenic	0.993
LRP5	O75197-1.2	V1061D	Pathogenic	0.996
LRP5	O75197-1.2	V1061E	Pathogenic	0.99
LRP5	O75197-1.2	V1061F	Pathogenic	0.99
LRP5	O75197-1.2	V1061G	Pathogenic	0.998
LRP5	O75197-1.2	V1061H	Pathogenic	0.998
LRP5	O75197-1.2	V1061I	Pathogenic	0.535
LRP5	O75197-1.2	V1061K	Pathogenic	0.986
LRP5	O75197-1.2	V1061L	Pathogenic	0.921
LRP5	O75197-1.2	V1061M	Pathogenic	0.947
LRP5	O75197-1.2	V1061N	Pathogenic	0.997
LRP5	O75197-1.2	V1061P	Pathogenic	0.997
LRP5	O75197-1.2	V1061Q	Pathogenic	0.993
LRP5	O75197-1.2	V1061R	Pathogenic	0.995
LRP5	O75197-1.2	V1061S	Pathogenic	0.994
LRP5	O75197-1.2	V1061T	Pathogenic	0.959
LRP5	O75197-1.2	V1061W	Pathogenic	0.998
LRP5	O75197-1.2	V1061Y	Pathogenic	0.992
LRP5	O75197-1.2	L1062A	Pathogenic	0.761
LRP5	O75197-1.2	L1062C	Pathogenic	0.857
LRP5	O75197-1.2	L1062D	Pathogenic	0.973
LRP5	O75197-1.2	L1062E	Pathogenic	0.931
LRP5	O75197-1.2	L1062F	Pathogenic	0.783
LRP5	O75197-1.2	L1062G	Pathogenic	0.985
LRP5	O75197-1.2	L1062H	Pathogenic	0.965
LRP5	O75197-1.2	L1062I	Neutral	0.282
LRP5	O75197-1.2	L1062K	Pathogenic	0.765
LRP5	O75197-1.2	L1062M	Neutral	0.22
LRP5	O75197-1.2	L1062N	Pathogenic	0.932
LRP5	O75197-1.2	L1062P	Pathogenic	0.978
LRP5	O75197-1.2	L1062Q	Pathogenic	0.867
LRP5	O75197-1.2	L1062R	Pathogenic	0.759
LRP5	O75197-1.2	L1062S	Pathogenic	0.878
LRP5	O75197-1.2	L1062T	Pathogenic	0.76
LRP5	O75197-1.2	L1062V	Neutral	0.451
LRP5	O75197-1.2	L1062W	Pathogenic	0.955
LRP5	O75197-1.2	L1062Y	Pathogenic	0.859
LRP5	O75197-1.2	R1063A	Neutral	0.289
LRP5	O75197-1.2	R1063C	Pathogenic	0.68
LRP5	O75197-1.2	R1063D	Pathogenic	0.771
LRP5	O75197-1.2	R1063E	Neutral	0.25
LRP5	O75197-1.2	R1063F	Pathogenic	0.528
LRP5	O75197-1.2	R1063G	Pathogenic	0.613
LRP5	O75197-1.2	R1063H	Neutral	0.145
LRP5	O75197-1.2	R1063I	Pathogenic	0.52
LRP5	O75197-1.2	R1063K	Neutral	0.049
LRP5	O75197-1.2	R1063L	Neutral	0.281
LRP5	O75197-1.2	R1063M	Neutral	0.163
LRP5	O75197-1.2	R1063N	Neutral	0.24
LRP5	O75197-1.2	R1063P	Neutral	0.471
LRP5	O75197-1.2	R1063Q	Neutral	0.071
LRP5	O75197-1.2	R1063S	Neutral	0.359
LRP5	O75197-1.2	R1063T	Neutral	0.308
LRP5	O75197-1.2	R1063V	Pathogenic	0.64
LRP5	O75197-1.2	R1063W	Neutral	0.424
LRP5	O75197-1.2	R1063Y	Neutral	0.438
LRP5	O75197-1.2	G1064A	Pathogenic	0.782
LRP5	O75197-1.2	G1064C	Pathogenic	0.982
LRP5	O75197-1.2	G1064D	Pathogenic	0.874
LRP5	O75197-1.2	G1064E	Pathogenic	0.959
LRP5	O75197-1.2	G1064F	Pathogenic	0.96
LRP5	O75197-1.2	G1064H	Pathogenic	0.973
LRP5	O75197-1.2	G1064I	Pathogenic	0.987
LRP5	O75197-1.2	G1064K	Pathogenic	0.942
LRP5	O75197-1.2	G1064L	Pathogenic	0.988
LRP5	O75197-1.2	G1064M	Pathogenic	0.976
LRP5	O75197-1.2	G1064N	Pathogenic	0.725
LRP5	O75197-1.2	G1064P	Pathogenic	0.957
LRP5	O75197-1.2	G1064Q	Pathogenic	0.971
LRP5	O75197-1.2	G1064R	Pathogenic	0.94
LRP5	O75197-1.2	G1064S	Pathogenic	0.819
LRP5	O75197-1.2	G1064T	Pathogenic	0.971
LRP5	O75197-1.2	G1064V	Pathogenic	0.977
LRP5	O75197-1.2	G1064W	Pathogenic	0.834
LRP5	O75197-1.2	G1064Y	Pathogenic	0.98
LRP5	O75197-1.2	D1065A	Pathogenic	0.718
LRP5	O75197-1.2	D1065C	Pathogenic	0.814
LRP5	O75197-1.2	D1065E	Neutral	0.065
LRP5	O75197-1.2	D1065F	Pathogenic	0.666
LRP5	O75197-1.2	D1065G	Pathogenic	0.517
LRP5	O75197-1.2	D1065H	Neutral	0.494
LRP5	O75197-1.2	D1065I	Pathogenic	0.667
LRP5	O75197-1.2	D1065K	Pathogenic	0.636
LRP5	O75197-1.2	D1065L	Pathogenic	0.87
LRP5	O75197-1.2	D1065M	Pathogenic	0.77
LRP5	O75197-1.2	D1065N	Neutral	0.174
LRP5	O75197-1.2	D1065P	Neutral	0.376
LRP5	O75197-1.2	D1065Q	Neutral	0.306
LRP5	O75197-1.2	D1065R	Pathogenic	0.837
LRP5	O75197-1.2	D1065S	Neutral	0.274
LRP5	O75197-1.2	D1065T	Neutral	0.476
LRP5	O75197-1.2	D1065V	Pathogenic	0.777
LRP5	O75197-1.2	D1065W	Pathogenic	0.793
LRP5	O75197-1.2	D1065Y	Pathogenic	0.806
LRP5	O75197-1.2	R1066A	Neutral	0.009
LRP5	O75197-1.2	R1066C	Neutral	0.045
LRP5	O75197-1.2	R1066D	Neutral	0.069
LRP5	O75197-1.2	R1066E	Neutral	0.007
LRP5	O75197-1.2	R1066F	Neutral	0.024
LRP5	O75197-1.2	R1066G	Neutral	0.034
LRP5	O75197-1.2	R1066H	Neutral	0.004
LRP5	O75197-1.2	R1066I	Neutral	0.023
LRP5	O75197-1.2	R1066K	Neutral	0.001
LRP5	O75197-1.2	R1066L	Neutral	0.009
LRP5	O75197-1.2	R1066M	Neutral	0.004
LRP5	O75197-1.2	R1066N	Neutral	0.007
LRP5	O75197-1.2	R1066P	Neutral	0.019
LRP5	O75197-1.2	R1066Q	Neutral	0.002
LRP5	O75197-1.2	R1066S	Neutral	0.012
LRP5	O75197-1.2	R1066T	Neutral	0.01
LRP5	O75197-1.2	R1066V	Neutral	0.038
LRP5	O75197-1.2	R1066W	Neutral	0.016
LRP5	O75197-1.2	R1066Y	Neutral	0.017
LRP5	O75197-1.2	D1067A	Pathogenic	0.948
LRP5	O75197-1.2	D1067C	Pathogenic	0.969
LRP5	O75197-1.2	D1067E	Neutral	0.336
LRP5	O75197-1.2	D1067F	Pathogenic	0.935
LRP5	O75197-1.2	D1067G	Pathogenic	0.885
LRP5	O75197-1.2	D1067H	Pathogenic	0.876
LRP5	O75197-1.2	D1067I	Pathogenic	0.935
LRP5	O75197-1.2	D1067K	Pathogenic	0.927
LRP5	O75197-1.2	D1067L	Pathogenic	0.98
LRP5	O75197-1.2	D1067M	Pathogenic	0.96
LRP5	O75197-1.2	D1067N	Pathogenic	0.603
LRP5	O75197-1.2	D1067P	Pathogenic	0.813
LRP5	O75197-1.2	D1067Q	Pathogenic	0.762
LRP5	O75197-1.2	D1067R	Pathogenic	0.974
LRP5	O75197-1.2	D1067S	Pathogenic	0.732
LRP5	O75197-1.2	D1067T	Pathogenic	0.868
LRP5	O75197-1.2	D1067V	Pathogenic	0.962
LRP5	O75197-1.2	D1067W	Pathogenic	0.965
LRP5	O75197-1.2	D1067Y	Pathogenic	0.968
LRP5	O75197-1.2	K1068A	Pathogenic	0.84
LRP5	O75197-1.2	K1068C	Pathogenic	0.965
LRP5	O75197-1.2	K1068D	Pathogenic	0.935
LRP5	O75197-1.2	K1068E	Pathogenic	0.587
LRP5	O75197-1.2	K1068F	Pathogenic	0.935
LRP5	O75197-1.2	K1068G	Pathogenic	0.953
LRP5	O75197-1.2	K1068H	Pathogenic	0.87
LRP5	O75197-1.2	K1068I	Pathogenic	0.933
LRP5	O75197-1.2	K1068L	Pathogenic	0.835
LRP5	O75197-1.2	K1068M	Pathogenic	0.717
LRP5	O75197-1.2	K1068N	Pathogenic	0.804
LRP5	O75197-1.2	K1068P	Pathogenic	0.791
LRP5	O75197-1.2	K1068Q	Neutral	0.496
LRP5	O75197-1.2	K1068R	Neutral	0.392
LRP5	O75197-1.2	K1068S	Pathogenic	0.704
LRP5	O75197-1.2	K1068T	Pathogenic	0.852
LRP5	O75197-1.2	K1068V	Pathogenic	0.883
LRP5	O75197-1.2	K1068W	Pathogenic	0.901
LRP5	O75197-1.2	K1068Y	Pathogenic	0.908
LRP5	O75197-1.2	P1069A	Pathogenic	0.997
LRP5	O75197-1.2	P1069C	Pathogenic	1.0
LRP5	O75197-1.2	P1069D	Pathogenic	0.992
LRP5	O75197-1.2	P1069E	Pathogenic	0.992
LRP5	O75197-1.2	P1069F	Pathogenic	1.0
LRP5	O75197-1.2	P1069G	Pathogenic	0.999
LRP5	O75197-1.2	P1069H	Pathogenic	0.999
LRP5	O75197-1.2	P1069I	Pathogenic	0.999
LRP5	O75197-1.2	P1069K	Pathogenic	0.989
LRP5	O75197-1.2	P1069L	Pathogenic	0.999
LRP5	O75197-1.2	P1069M	Pathogenic	0.999
LRP5	O75197-1.2	P1069N	Pathogenic	0.998
LRP5	O75197-1.2	P1069Q	Pathogenic	0.995
LRP5	O75197-1.2	P1069R	Pathogenic	0.996
LRP5	O75197-1.2	P1069S	Pathogenic	0.996
LRP5	O75197-1.2	P1069T	Pathogenic	0.997
LRP5	O75197-1.2	P1069V	Pathogenic	0.999
LRP5	O75197-1.2	P1069W	Pathogenic	1.0
LRP5	O75197-1.2	P1069Y	Pathogenic	1.0
LRP5	O75197-1.2	R1070A	Pathogenic	0.992
LRP5	O75197-1.2	R1070C	Pathogenic	0.998
LRP5	O75197-1.2	R1070D	Pathogenic	0.999
LRP5	O75197-1.2	R1070E	Pathogenic	0.99
LRP5	O75197-1.2	R1070F	Pathogenic	0.997
LRP5	O75197-1.2	R1070G	Pathogenic	0.998
LRP5	O75197-1.2	R1070H	Pathogenic	0.981
LRP5	O75197-1.2	R1070I	Pathogenic	0.997
LRP5	O75197-1.2	R1070K	Pathogenic	0.938
LRP5	O75197-1.2	R1070L	Pathogenic	0.991
LRP5	O75197-1.2	R1070M	Pathogenic	0.983
LRP5	O75197-1.2	R1070N	Pathogenic	0.989
LRP5	O75197-1.2	R1070P	Pathogenic	0.996
LRP5	O75197-1.2	R1070Q	Pathogenic	0.958
LRP5	O75197-1.2	R1070S	Pathogenic	0.994
LRP5	O75197-1.2	R1070T	Pathogenic	0.992
LRP5	O75197-1.2	R1070V	Pathogenic	0.998
LRP5	O75197-1.2	R1070W	Pathogenic	0.995
LRP5	O75197-1.2	R1070Y	Pathogenic	0.996
LRP5	O75197-1.2	A1071C	Pathogenic	0.817
LRP5	O75197-1.2	A1071D	Pathogenic	0.966
LRP5	O75197-1.2	A1071E	Pathogenic	0.911
LRP5	O75197-1.2	A1071F	Pathogenic	0.949
LRP5	O75197-1.2	A1071G	Pathogenic	0.861
LRP5	O75197-1.2	A1071H	Pathogenic	0.984
LRP5	O75197-1.2	A1071I	Pathogenic	0.859
LRP5	O75197-1.2	A1071K	Pathogenic	0.878
LRP5	O75197-1.2	A1071L	Pathogenic	0.87
LRP5	O75197-1.2	A1071M	Pathogenic	0.911
LRP5	O75197-1.2	A1071N	Pathogenic	0.97
LRP5	O75197-1.2	A1071P	Pathogenic	0.945
LRP5	O75197-1.2	A1071Q	Pathogenic	0.937
LRP5	O75197-1.2	A1071R	Pathogenic	0.874
LRP5	O75197-1.2	A1071S	Pathogenic	0.667
LRP5	O75197-1.2	A1071T	Pathogenic	0.885
LRP5	O75197-1.2	A1071V	Pathogenic	0.778
LRP5	O75197-1.2	A1071W	Pathogenic	0.973
LRP5	O75197-1.2	A1071Y	Pathogenic	0.975
LRP5	O75197-1.2	I1072A	Pathogenic	0.977
LRP5	O75197-1.2	I1072C	Pathogenic	0.987
LRP5	O75197-1.2	I1072D	Pathogenic	0.994
LRP5	O75197-1.2	I1072E	Pathogenic	0.994
LRP5	O75197-1.2	I1072F	Pathogenic	0.982
LRP5	O75197-1.2	I1072G	Pathogenic	0.999
LRP5	O75197-1.2	I1072H	Pathogenic	0.997
LRP5	O75197-1.2	I1072K	Pathogenic	0.992
LRP5	O75197-1.2	I1072L	Pathogenic	0.85
LRP5	O75197-1.2	I1072M	Pathogenic	0.919
LRP5	O75197-1.2	I1072N	Pathogenic	0.994
LRP5	O75197-1.2	I1072P	Pathogenic	0.998
LRP5	O75197-1.2	I1072Q	Pathogenic	0.996
LRP5	O75197-1.2	I1072R	Pathogenic	0.992
LRP5	O75197-1.2	I1072S	Pathogenic	0.99
LRP5	O75197-1.2	I1072T	Pathogenic	0.977
LRP5	O75197-1.2	I1072V	Pathogenic	0.539
LRP5	O75197-1.2	I1072W	Pathogenic	0.999
LRP5	O75197-1.2	I1072Y	Pathogenic	0.988
LRP5	O75197-1.2	V1073A	Pathogenic	0.703
LRP5	O75197-1.2	V1073C	Pathogenic	0.931
LRP5	O75197-1.2	V1073D	Pathogenic	0.964
LRP5	O75197-1.2	V1073E	Pathogenic	0.909
LRP5	O75197-1.2	V1073F	Pathogenic	0.908
LRP5	O75197-1.2	V1073G	Pathogenic	0.98
LRP5	O75197-1.2	V1073H	Pathogenic	0.983
LRP5	O75197-1.2	V1073I	Neutral	0.104
LRP5	O75197-1.2	V1073K	Pathogenic	0.874
LRP5	O75197-1.2	V1073L	Pathogenic	0.54
LRP5	O75197-1.2	V1073M	Pathogenic	0.641
LRP5	O75197-1.2	V1073N	Pathogenic	0.969
LRP5	O75197-1.2	V1073P	Pathogenic	0.97
LRP5	O75197-1.2	V1073Q	Pathogenic	0.935
LRP5	O75197-1.2	V1073R	Pathogenic	0.953
LRP5	O75197-1.2	V1073S	Pathogenic	0.942
LRP5	O75197-1.2	V1073T	Pathogenic	0.703
LRP5	O75197-1.2	V1073W	Pathogenic	0.983
LRP5	O75197-1.2	V1073Y	Pathogenic	0.928
LRP5	O75197-1.2	V1074A	Pathogenic	0.827
LRP5	O75197-1.2	V1074C	Pathogenic	0.965
LRP5	O75197-1.2	V1074D	Pathogenic	0.982
LRP5	O75197-1.2	V1074E	Pathogenic	0.953
LRP5	O75197-1.2	V1074F	Pathogenic	0.952
LRP5	O75197-1.2	V1074G	Pathogenic	0.99
LRP5	O75197-1.2	V1074H	Pathogenic	0.992
LRP5	O75197-1.2	V1074I	Neutral	0.19
LRP5	O75197-1.2	V1074K	Pathogenic	0.934
LRP5	O75197-1.2	V1074L	Pathogenic	0.704
LRP5	O75197-1.2	V1074M	Pathogenic	0.783
LRP5	O75197-1.2	V1074N	Pathogenic	0.984
LRP5	O75197-1.2	V1074P	Pathogenic	0.985
LRP5	O75197-1.2	V1074Q	Pathogenic	0.967
LRP5	O75197-1.2	V1074R	Pathogenic	0.976
LRP5	O75197-1.2	V1074S	Pathogenic	0.971
LRP5	O75197-1.2	V1074T	Pathogenic	0.827
LRP5	O75197-1.2	V1074W	Pathogenic	0.992
LRP5	O75197-1.2	V1074Y	Pathogenic	0.963
LRP5	O75197-1.2	N1075A	Pathogenic	0.966
LRP5	O75197-1.2	N1075C	Pathogenic	0.98
LRP5	O75197-1.2	N1075D	Pathogenic	0.67
LRP5	O75197-1.2	N1075E	Pathogenic	0.873
LRP5	O75197-1.2	N1075F	Pathogenic	0.958
LRP5	O75197-1.2	N1075G	Pathogenic	0.796
LRP5	O75197-1.2	N1075H	Pathogenic	0.543
LRP5	O75197-1.2	N1075I	Pathogenic	0.958
LRP5	O75197-1.2	N1075K	Pathogenic	0.827
LRP5	O75197-1.2	N1075L	Pathogenic	0.961
LRP5	O75197-1.2	N1075M	Pathogenic	0.925
LRP5	O75197-1.2	N1075P	Pathogenic	0.953
LRP5	O75197-1.2	N1075Q	Pathogenic	0.833
LRP5	O75197-1.2	N1075R	Pathogenic	0.823
LRP5	O75197-1.2	N1075S	Pathogenic	0.58
LRP5	O75197-1.2	N1075T	Pathogenic	0.77
LRP5	O75197-1.2	N1075V	Pathogenic	0.975
LRP5	O75197-1.2	N1075W	Pathogenic	0.977
LRP5	O75197-1.2	N1075Y	Pathogenic	0.939
LRP5	O75197-1.2	A1076C	Neutral	0.351
LRP5	O75197-1.2	A1076D	Pathogenic	0.776
LRP5	O75197-1.2	A1076E	Pathogenic	0.555
LRP5	O75197-1.2	A1076F	Pathogenic	0.692
LRP5	O75197-1.2	A1076G	Neutral	0.429
LRP5	O75197-1.2	A1076H	Pathogenic	0.881
LRP5	O75197-1.2	A1076I	Neutral	0.426
LRP5	O75197-1.2	A1076K	Neutral	0.466
LRP5	O75197-1.2	A1076L	Neutral	0.449
LRP5	O75197-1.2	A1076M	Pathogenic	0.554
LRP5	O75197-1.2	A1076N	Pathogenic	0.8
LRP5	O75197-1.2	A1076P	Pathogenic	0.674
LRP5	O75197-1.2	A1076Q	Pathogenic	0.642
LRP5	O75197-1.2	A1076R	Neutral	0.457
LRP5	O75197-1.2	A1076S	Neutral	0.196
LRP5	O75197-1.2	A1076T	Neutral	0.483
LRP5	O75197-1.2	A1076V	Neutral	0.299
LRP5	O75197-1.2	A1076W	Pathogenic	0.813
LRP5	O75197-1.2	A1076Y	Pathogenic	0.824
LRP5	O75197-1.2	E1077A	Pathogenic	0.971
LRP5	O75197-1.2	E1077C	Pathogenic	0.998
LRP5	O75197-1.2	E1077D	Pathogenic	0.72
LRP5	O75197-1.2	E1077F	Pathogenic	0.988
LRP5	O75197-1.2	E1077G	Pathogenic	0.992
LRP5	O75197-1.2	E1077H	Pathogenic	0.932
LRP5	O75197-1.2	E1077I	Pathogenic	0.988
LRP5	O75197-1.2	E1077K	Pathogenic	0.864
LRP5	O75197-1.2	E1077L	Pathogenic	0.989
LRP5	O75197-1.2	E1077M	Pathogenic	0.979
LRP5	O75197-1.2	E1077N	Pathogenic	0.963
LRP5	O75197-1.2	E1077P	Pathogenic	0.96
LRP5	O75197-1.2	E1077Q	Pathogenic	0.67
LRP5	O75197-1.2	E1077R	Pathogenic	0.949
LRP5	O75197-1.2	E1077S	Pathogenic	0.938
LRP5	O75197-1.2	E1077T	Pathogenic	0.973
LRP5	O75197-1.2	E1077V	Pathogenic	0.98
LRP5	O75197-1.2	E1077W	Pathogenic	0.982
LRP5	O75197-1.2	E1077Y	Pathogenic	0.983
LRP5	O75197-1.2	R1078A	Pathogenic	0.555
LRP5	O75197-1.2	R1078C	Pathogenic	0.867
LRP5	O75197-1.2	R1078D	Pathogenic	0.912
LRP5	O75197-1.2	R1078E	Pathogenic	0.506
LRP5	O75197-1.2	R1078F	Pathogenic	0.774
LRP5	O75197-1.2	R1078G	Pathogenic	0.829
LRP5	O75197-1.2	R1078H	Neutral	0.343
LRP5	O75197-1.2	R1078I	Pathogenic	0.769
LRP5	O75197-1.2	R1078K	Neutral	0.136
LRP5	O75197-1.2	R1078L	Pathogenic	0.545
LRP5	O75197-1.2	R1078M	Neutral	0.374
LRP5	O75197-1.2	R1078N	Neutral	0.492
LRP5	O75197-1.2	R1078P	Pathogenic	0.732
LRP5	O75197-1.2	R1078Q	Neutral	0.189
LRP5	O75197-1.2	R1078S	Pathogenic	0.632
LRP5	O75197-1.2	R1078T	Pathogenic	0.577
LRP5	O75197-1.2	R1078V	Pathogenic	0.845
LRP5	O75197-1.2	R1078W	Pathogenic	0.693
LRP5	O75197-1.2	R1078Y	Pathogenic	0.705
LRP5	O75197-1.2	G1079A	Pathogenic	0.963
LRP5	O75197-1.2	G1079C	Pathogenic	0.997
LRP5	O75197-1.2	G1079D	Pathogenic	0.981
LRP5	O75197-1.2	G1079E	Pathogenic	0.994
LRP5	O75197-1.2	G1079F	Pathogenic	0.994
LRP5	O75197-1.2	G1079H	Pathogenic	0.996
LRP5	O75197-1.2	G1079I	Pathogenic	0.998
LRP5	O75197-1.2	G1079K	Pathogenic	0.992
LRP5	O75197-1.2	G1079L	Pathogenic	0.998
LRP5	O75197-1.2	G1079M	Pathogenic	0.997
LRP5	O75197-1.2	G1079N	Pathogenic	0.951
LRP5	O75197-1.2	G1079P	Pathogenic	0.994
LRP5	O75197-1.2	G1079Q	Pathogenic	0.996
LRP5	O75197-1.2	G1079R	Pathogenic	0.991
LRP5	O75197-1.2	G1079S	Pathogenic	0.971
LRP5	O75197-1.2	G1079T	Pathogenic	0.996
LRP5	O75197-1.2	G1079V	Pathogenic	0.997
LRP5	O75197-1.2	G1079W	Pathogenic	0.974
LRP5	O75197-1.2	G1079Y	Pathogenic	0.997
LRP5	O75197-1.2	Y1080A	Pathogenic	0.987
LRP5	O75197-1.2	Y1080C	Pathogenic	0.993
LRP5	O75197-1.2	Y1080D	Pathogenic	0.989
LRP5	O75197-1.2	Y1080E	Pathogenic	0.973
LRP5	O75197-1.2	Y1080F	Neutral	0.22
LRP5	O75197-1.2	Y1080G	Pathogenic	0.994
LRP5	O75197-1.2	Y1080H	Neutral	0.456
LRP5	O75197-1.2	Y1080I	Pathogenic	0.959
LRP5	O75197-1.2	Y1080K	Pathogenic	0.964
LRP5	O75197-1.2	Y1080L	Pathogenic	0.963
LRP5	O75197-1.2	Y1080M	Pathogenic	0.975
LRP5	O75197-1.2	Y1080N	Pathogenic	0.973
LRP5	O75197-1.2	Y1080P	Pathogenic	0.997
LRP5	O75197-1.2	Y1080Q	Pathogenic	0.945
LRP5	O75197-1.2	Y1080R	Pathogenic	0.964
LRP5	O75197-1.2	Y1080S	Pathogenic	0.983
LRP5	O75197-1.2	Y1080T	Pathogenic	0.987
LRP5	O75197-1.2	Y1080V	Pathogenic	0.975
LRP5	O75197-1.2	Y1080W	Neutral	0.357
LRP5	O75197-1.2	L1081A	Neutral	0.377
LRP5	O75197-1.2	L1081C	Pathogenic	0.533
LRP5	O75197-1.2	L1081D	Pathogenic	0.871
LRP5	O75197-1.2	L1081E	Pathogenic	0.72
LRP5	O75197-1.2	L1081F	Neutral	0.408
LRP5	O75197-1.2	L1081G	Pathogenic	0.926
LRP5	O75197-1.2	L1081H	Pathogenic	0.839
LRP5	O75197-1.2	L1081I	Neutral	0.07
LRP5	O75197-1.2	L1081K	Neutral	0.383
LRP5	O75197-1.2	L1081M	Neutral	0.051
LRP5	O75197-1.2	L1081N	Pathogenic	0.723
LRP5	O75197-1.2	L1081P	Pathogenic	0.894
LRP5	O75197-1.2	L1081Q	Pathogenic	0.554
LRP5	O75197-1.2	L1081R	Neutral	0.375
LRP5	O75197-1.2	L1081S	Pathogenic	0.578
LRP5	O75197-1.2	L1081T	Neutral	0.376
LRP5	O75197-1.2	L1081V	Neutral	0.136
LRP5	O75197-1.2	L1081W	Pathogenic	0.801
LRP5	O75197-1.2	L1081Y	Pathogenic	0.537
LRP5	O75197-1.2	Y1082A	Pathogenic	0.994
LRP5	O75197-1.2	Y1082C	Pathogenic	0.997
LRP5	O75197-1.2	Y1082D	Pathogenic	0.995
LRP5	O75197-1.2	Y1082E	Pathogenic	0.988
LRP5	O75197-1.2	Y1082F	Neutral	0.397
LRP5	O75197-1.2	Y1082G	Pathogenic	0.998
LRP5	O75197-1.2	Y1082H	Pathogenic	0.661
LRP5	O75197-1.2	Y1082I	Pathogenic	0.982
LRP5	O75197-1.2	Y1082K	Pathogenic	0.984
LRP5	O75197-1.2	Y1082L	Pathogenic	0.984
LRP5	O75197-1.2	Y1082M	Pathogenic	0.989
LRP5	O75197-1.2	Y1082N	Pathogenic	0.988
LRP5	O75197-1.2	Y1082P	Pathogenic	0.999
LRP5	O75197-1.2	Y1082Q	Pathogenic	0.976
LRP5	O75197-1.2	Y1082R	Pathogenic	0.984
LRP5	O75197-1.2	Y1082S	Pathogenic	0.993
LRP5	O75197-1.2	Y1082T	Pathogenic	0.994
LRP5	O75197-1.2	Y1082V	Pathogenic	0.989
LRP5	O75197-1.2	Y1082W	Pathogenic	0.564
LRP5	O75197-1.2	F1083A	Pathogenic	0.992
LRP5	O75197-1.2	F1083C	Pathogenic	0.996
LRP5	O75197-1.2	F1083D	Pathogenic	0.994
LRP5	O75197-1.2	F1083E	Pathogenic	0.994
LRP5	O75197-1.2	F1083G	Pathogenic	0.997
LRP5	O75197-1.2	F1083H	Pathogenic	0.975
LRP5	O75197-1.2	F1083I	Pathogenic	0.983
LRP5	O75197-1.2	F1083K	Pathogenic	0.993
LRP5	O75197-1.2	F1083L	Pathogenic	0.981
LRP5	O75197-1.2	F1083M	Pathogenic	0.972
LRP5	O75197-1.2	F1083N	Pathogenic	0.995
LRP5	O75197-1.2	F1083P	Pathogenic	0.999
LRP5	O75197-1.2	F1083Q	Pathogenic	0.996
LRP5	O75197-1.2	F1083R	Pathogenic	0.992
LRP5	O75197-1.2	F1083S	Pathogenic	0.99
LRP5	O75197-1.2	F1083T	Pathogenic	0.992
LRP5	O75197-1.2	F1083V	Pathogenic	0.99
LRP5	O75197-1.2	F1083W	Pathogenic	0.924
LRP5	O75197-1.2	F1083Y	Neutral	0.494
LRP5	O75197-1.2	T1084A	Pathogenic	0.989
LRP5	O75197-1.2	T1084C	Pathogenic	0.994
LRP5	O75197-1.2	T1084D	Pathogenic	0.992
LRP5	O75197-1.2	T1084E	Pathogenic	0.992
LRP5	O75197-1.2	T1084F	Pathogenic	0.995
LRP5	O75197-1.2	T1084G	Pathogenic	0.999
LRP5	O75197-1.2	T1084H	Pathogenic	0.999
LRP5	O75197-1.2	T1084I	Pathogenic	0.986
LRP5	O75197-1.2	T1084K	Pathogenic	0.989
LRP5	O75197-1.2	T1084L	Pathogenic	0.987
LRP5	O75197-1.2	T1084M	Pathogenic	0.992
LRP5	O75197-1.2	T1084N	Pathogenic	0.978
LRP5	O75197-1.2	T1084P	Pathogenic	0.995
LRP5	O75197-1.2	T1084Q	Pathogenic	0.995
LRP5	O75197-1.2	T1084R	Pathogenic	0.989
LRP5	O75197-1.2	T1084S	Pathogenic	0.96
LRP5	O75197-1.2	T1084V	Pathogenic	0.976
LRP5	O75197-1.2	T1084W	Pathogenic	0.993
LRP5	O75197-1.2	T1084Y	Pathogenic	0.998
LRP5	O75197-1.2	N1085A	Pathogenic	0.966
LRP5	O75197-1.2	N1085C	Pathogenic	0.98
LRP5	O75197-1.2	N1085D	Pathogenic	0.67
LRP5	O75197-1.2	N1085E	Pathogenic	0.873
LRP5	O75197-1.2	N1085F	Pathogenic	0.958
LRP5	O75197-1.2	N1085G	Pathogenic	0.796
LRP5	O75197-1.2	N1085H	Pathogenic	0.544
LRP5	O75197-1.2	N1085I	Pathogenic	0.958
LRP5	O75197-1.2	N1085K	Pathogenic	0.828
LRP5	O75197-1.2	N1085L	Pathogenic	0.961
LRP5	O75197-1.2	N1085M	Pathogenic	0.925
LRP5	O75197-1.2	N1085P	Pathogenic	0.953
LRP5	O75197-1.2	N1085Q	Pathogenic	0.833
LRP5	O75197-1.2	N1085R	Pathogenic	0.823
LRP5	O75197-1.2	N1085S	Pathogenic	0.58
LRP5	O75197-1.2	N1085T	Pathogenic	0.77
LRP5	O75197-1.2	N1085V	Pathogenic	0.975
LRP5	O75197-1.2	N1085W	Pathogenic	0.977
LRP5	O75197-1.2	N1085Y	Pathogenic	0.939
LRP5	O75197-1.2	M1086A	Pathogenic	0.644
LRP5	O75197-1.2	M1086C	Pathogenic	0.773
LRP5	O75197-1.2	M1086D	Pathogenic	0.869
LRP5	O75197-1.2	M1086E	Pathogenic	0.717
LRP5	O75197-1.2	M1086F	Neutral	0.471
LRP5	O75197-1.2	M1086G	Pathogenic	0.925
LRP5	O75197-1.2	M1086H	Pathogenic	0.836
LRP5	O75197-1.2	M1086I	Neutral	0.227
LRP5	O75197-1.2	M1086K	Neutral	0.379
LRP5	O75197-1.2	M1086L	Neutral	0.096
LRP5	O75197-1.2	M1086N	Pathogenic	0.719
LRP5	O75197-1.2	M1086P	Pathogenic	0.892
LRP5	O75197-1.2	M1086Q	Neutral	0.286
LRP5	O75197-1.2	M1086R	Neutral	0.371
LRP5	O75197-1.2	M1086S	Pathogenic	0.573
LRP5	O75197-1.2	M1086T	Pathogenic	0.643
LRP5	O75197-1.2	M1086V	Neutral	0.319
LRP5	O75197-1.2	M1086W	Pathogenic	0.631
LRP5	O75197-1.2	M1086Y	Pathogenic	0.776
LRP5	O75197-1.2	Q1087A	Pathogenic	0.922
LRP5	O75197-1.2	Q1087C	Pathogenic	0.984
LRP5	O75197-1.2	Q1087D	Pathogenic	0.799
LRP5	O75197-1.2	Q1087E	Neutral	0.333
LRP5	O75197-1.2	Q1087F	Pathogenic	0.968
LRP5	O75197-1.2	Q1087G	Pathogenic	0.979
LRP5	O75197-1.2	Q1087H	Pathogenic	0.831
LRP5	O75197-1.2	Q1087I	Pathogenic	0.968
LRP5	O75197-1.2	Q1087K	Pathogenic	0.519
LRP5	O75197-1.2	Q1087L	Pathogenic	0.917
LRP5	O75197-1.2	Q1087M	Pathogenic	0.645
LRP5	O75197-1.2	Q1087N	Pathogenic	0.824
LRP5	O75197-1.2	Q1087P	Pathogenic	0.895
LRP5	O75197-1.2	Q1087R	Pathogenic	0.511
LRP5	O75197-1.2	Q1087S	Pathogenic	0.843
LRP5	O75197-1.2	Q1087T	Pathogenic	0.929
LRP5	O75197-1.2	Q1087V	Pathogenic	0.945
LRP5	O75197-1.2	Q1087W	Pathogenic	0.864
LRP5	O75197-1.2	Q1087Y	Pathogenic	0.873
LRP5	O75197-1.2	D1088A	Neutral	0.22
LRP5	O75197-1.2	D1088C	Neutral	0.326
LRP5	O75197-1.2	D1088E	Neutral	0.008
LRP5	O75197-1.2	D1088F	Neutral	0.181
LRP5	O75197-1.2	D1088G	Neutral	0.106
LRP5	O75197-1.2	D1088H	Neutral	0.097
LRP5	O75197-1.2	D1088I	Neutral	0.182
LRP5	O75197-1.2	D1088K	Neutral	0.162
LRP5	O75197-1.2	D1088L	Neutral	0.425
LRP5	O75197-1.2	D1088M	Neutral	0.27
LRP5	O75197-1.2	D1088N	Neutral	0.023
LRP5	O75197-1.2	D1088P	Neutral	0.062
LRP5	O75197-1.2	D1088Q	Neutral	0.047
LRP5	O75197-1.2	D1088R	Neutral	0.362
LRP5	O75197-1.2	D1088S	Neutral	0.04
LRP5	O75197-1.2	D1088T	Neutral	0.091
LRP5	O75197-1.2	D1088V	Neutral	0.279
LRP5	O75197-1.2	D1088W	Neutral	0.298
LRP5	O75197-1.2	D1088Y	Neutral	0.315
LRP5	O75197-1.2	R1089A	Pathogenic	0.721
LRP5	O75197-1.2	R1089C	Pathogenic	0.931
LRP5	O75197-1.2	R1089D	Pathogenic	0.955
LRP5	O75197-1.2	R1089E	Pathogenic	0.679
LRP5	O75197-1.2	R1089F	Pathogenic	0.876
LRP5	O75197-1.2	R1089G	Pathogenic	0.909
LRP5	O75197-1.2	R1089H	Pathogenic	0.519
LRP5	O75197-1.2	R1089I	Pathogenic	0.873
LRP5	O75197-1.2	R1089K	Neutral	0.246
LRP5	O75197-1.2	R1089L	Pathogenic	0.712
LRP5	O75197-1.2	R1089M	Pathogenic	0.553
LRP5	O75197-1.2	R1089N	Pathogenic	0.667
LRP5	O75197-1.2	R1089P	Pathogenic	0.849
LRP5	O75197-1.2	R1089Q	Neutral	0.325
LRP5	O75197-1.2	R1089S	Pathogenic	0.78
LRP5	O75197-1.2	R1089T	Pathogenic	0.738
LRP5	O75197-1.2	R1089V	Pathogenic	0.918
LRP5	O75197-1.2	R1089W	Pathogenic	0.824
LRP5	O75197-1.2	R1089Y	Pathogenic	0.831
LRP5	O75197-1.2	A1090C	Neutral	0.064
LRP5	O75197-1.2	A1090D	Neutral	0.306
LRP5	O75197-1.2	A1090E	Neutral	0.137
LRP5	O75197-1.2	A1090F	Neutral	0.223
LRP5	O75197-1.2	A1090G	Neutral	0.087
LRP5	O75197-1.2	A1090H	Neutral	0.486
LRP5	O75197-1.2	A1090I	Neutral	0.086
LRP5	O75197-1.2	A1090K	Neutral	0.1
LRP5	O75197-1.2	A1090L	Neutral	0.094
LRP5	O75197-1.2	A1090M	Neutral	0.136
LRP5	O75197-1.2	A1090N	Neutral	0.337
LRP5	O75197-1.2	A1090P	Neutral	0.209
LRP5	O75197-1.2	A1090Q	Neutral	0.186
LRP5	O75197-1.2	A1090R	Neutral	0.097
LRP5	O75197-1.2	A1090S	Neutral	0.03
LRP5	O75197-1.2	A1090T	Neutral	0.106
LRP5	O75197-1.2	A1090V	Neutral	0.051
LRP5	O75197-1.2	A1090W	Neutral	0.355
LRP5	O75197-1.2	A1090Y	Neutral	0.373
LRP5	O75197-1.2	A1091C	Neutral	0.23
LRP5	O75197-1.2	A1091D	Pathogenic	0.656
LRP5	O75197-1.2	A1091E	Neutral	0.407
LRP5	O75197-1.2	A1091F	Pathogenic	0.553
LRP5	O75197-1.2	A1091G	Neutral	0.293
LRP5	O75197-1.2	A1091H	Pathogenic	0.804
LRP5	O75197-1.2	A1091I	Neutral	0.29
LRP5	O75197-1.2	A1091K	Neutral	0.324
LRP5	O75197-1.2	A1091L	Neutral	0.31
LRP5	O75197-1.2	A1091M	Neutral	0.406
LRP5	O75197-1.2	A1091N	Pathogenic	0.688
LRP5	O75197-1.2	A1091P	Pathogenic	0.533
LRP5	O75197-1.2	A1091Q	Neutral	0.497
LRP5	O75197-1.2	A1091R	Neutral	0.317
LRP5	O75197-1.2	A1091S	Neutral	0.118
LRP5	O75197-1.2	A1091T	Neutral	0.34
LRP5	O75197-1.2	A1091V	Neutral	0.19
LRP5	O75197-1.2	A1091W	Pathogenic	0.705
LRP5	O75197-1.2	A1091Y	Pathogenic	0.72
LRP5	O75197-1.2	K1092A	Pathogenic	0.949
LRP5	O75197-1.2	K1092C	Pathogenic	0.99
LRP5	O75197-1.2	K1092D	Pathogenic	0.981
LRP5	O75197-1.2	K1092E	Pathogenic	0.835
LRP5	O75197-1.2	K1092F	Pathogenic	0.981
LRP5	O75197-1.2	K1092G	Pathogenic	0.986
LRP5	O75197-1.2	K1092H	Pathogenic	0.96
LRP5	O75197-1.2	K1092I	Pathogenic	0.98
LRP5	O75197-1.2	K1092L	Pathogenic	0.947
LRP5	O75197-1.2	K1092M	Pathogenic	0.9
LRP5	O75197-1.2	K1092N	Pathogenic	0.936
LRP5	O75197-1.2	K1092P	Pathogenic	0.931
LRP5	O75197-1.2	K1092Q	Pathogenic	0.778
LRP5	O75197-1.2	K1092R	Pathogenic	0.697
LRP5	O75197-1.2	K1092S	Pathogenic	0.895
LRP5	O75197-1.2	K1092T	Pathogenic	0.954
LRP5	O75197-1.2	K1092V	Pathogenic	0.964
LRP5	O75197-1.2	K1092W	Pathogenic	0.97
LRP5	O75197-1.2	K1092Y	Pathogenic	0.972
LRP5	O75197-1.2	I1093A	Pathogenic	0.972
LRP5	O75197-1.2	I1093C	Pathogenic	0.985
LRP5	O75197-1.2	I1093D	Pathogenic	0.992
LRP5	O75197-1.2	I1093E	Pathogenic	0.993
LRP5	O75197-1.2	I1093F	Pathogenic	0.979
LRP5	O75197-1.2	I1093G	Pathogenic	0.999
LRP5	O75197-1.2	I1093H	Pathogenic	0.997
LRP5	O75197-1.2	I1093K	Pathogenic	0.991
LRP5	O75197-1.2	I1093L	Pathogenic	0.826
LRP5	O75197-1.2	I1093M	Pathogenic	0.905
LRP5	O75197-1.2	I1093N	Pathogenic	0.993
LRP5	O75197-1.2	I1093P	Pathogenic	0.998
LRP5	O75197-1.2	I1093Q	Pathogenic	0.995
LRP5	O75197-1.2	I1093R	Pathogenic	0.991
LRP5	O75197-1.2	I1093S	Pathogenic	0.988
LRP5	O75197-1.2	I1093T	Pathogenic	0.972
LRP5	O75197-1.2	I1093V	Neutral	0.495
LRP5	O75197-1.2	I1093W	Pathogenic	0.999
LRP5	O75197-1.2	I1093Y	Pathogenic	0.985
LRP5	O75197-1.2	E1094A	Pathogenic	0.961
LRP5	O75197-1.2	E1094C	Pathogenic	0.997
LRP5	O75197-1.2	E1094D	Pathogenic	0.653
LRP5	O75197-1.2	E1094F	Pathogenic	0.984
LRP5	O75197-1.2	E1094G	Pathogenic	0.99
LRP5	O75197-1.2	E1094H	Pathogenic	0.909
LRP5	O75197-1.2	E1094I	Pathogenic	0.984
LRP5	O75197-1.2	E1094K	Pathogenic	0.823
LRP5	O75197-1.2	E1094L	Pathogenic	0.986
LRP5	O75197-1.2	E1094M	Pathogenic	0.972
LRP5	O75197-1.2	E1094N	Pathogenic	0.95
LRP5	O75197-1.2	E1094P	Pathogenic	0.947
LRP5	O75197-1.2	E1094Q	Pathogenic	0.598
LRP5	O75197-1.2	E1094R	Pathogenic	0.932
LRP5	O75197-1.2	E1094S	Pathogenic	0.918
LRP5	O75197-1.2	E1094T	Pathogenic	0.964
LRP5	O75197-1.2	E1094V	Pathogenic	0.973
LRP5	O75197-1.2	E1094W	Pathogenic	0.975
LRP5	O75197-1.2	E1094Y	Pathogenic	0.977
LRP5	O75197-1.2	R1095A	Pathogenic	0.849
LRP5	O75197-1.2	R1095C	Pathogenic	0.967
LRP5	O75197-1.2	R1095D	Pathogenic	0.979
LRP5	O75197-1.2	R1095E	Pathogenic	0.822
LRP5	O75197-1.2	R1095F	Pathogenic	0.939
LRP5	O75197-1.2	R1095G	Pathogenic	0.956
LRP5	O75197-1.2	R1095H	Pathogenic	0.701
LRP5	O75197-1.2	R1095I	Pathogenic	0.937
LRP5	O75197-1.2	R1095K	Neutral	0.416
LRP5	O75197-1.2	R1095L	Pathogenic	0.844
LRP5	O75197-1.2	R1095M	Pathogenic	0.73
LRP5	O75197-1.2	R1095N	Pathogenic	0.814
LRP5	O75197-1.2	R1095P	Pathogenic	0.925
LRP5	O75197-1.2	R1095Q	Pathogenic	0.512
LRP5	O75197-1.2	R1095S	Pathogenic	0.885
LRP5	O75197-1.2	R1095T	Pathogenic	0.86
LRP5	O75197-1.2	R1095V	Pathogenic	0.961
LRP5	O75197-1.2	R1095W	Pathogenic	0.911
LRP5	O75197-1.2	R1095Y	Pathogenic	0.915
LRP5	O75197-1.2	A1096C	Pathogenic	0.911
LRP5	O75197-1.2	A1096D	Pathogenic	0.985
LRP5	O75197-1.2	A1096E	Pathogenic	0.959
LRP5	O75197-1.2	A1096F	Pathogenic	0.977
LRP5	O75197-1.2	A1096G	Pathogenic	0.934
LRP5	O75197-1.2	A1096H	Pathogenic	0.993
LRP5	O75197-1.2	A1096I	Pathogenic	0.933
LRP5	O75197-1.2	A1096K	Pathogenic	0.943
LRP5	O75197-1.2	A1096L	Pathogenic	0.939
LRP5	O75197-1.2	A1096M	Pathogenic	0.959
LRP5	O75197-1.2	A1096N	Pathogenic	0.987
LRP5	O75197-1.2	A1096P	Pathogenic	0.975
LRP5	O75197-1.2	A1096Q	Pathogenic	0.971
LRP5	O75197-1.2	A1096R	Pathogenic	0.941
LRP5	O75197-1.2	A1096S	Pathogenic	0.821
LRP5	O75197-1.2	A1096T	Pathogenic	0.946
LRP5	O75197-1.2	A1096V	Pathogenic	0.889
LRP5	O75197-1.2	A1096W	Pathogenic	0.988
LRP5	O75197-1.2	A1096Y	Pathogenic	0.989
LRP5	O75197-1.2	A1097C	Neutral	0.496
LRP5	O75197-1.2	A1097D	Pathogenic	0.863
LRP5	O75197-1.2	A1097E	Pathogenic	0.693
LRP5	O75197-1.2	A1097F	Pathogenic	0.803
LRP5	O75197-1.2	A1097G	Pathogenic	0.577
LRP5	O75197-1.2	A1097H	Pathogenic	0.931
LRP5	O75197-1.2	A1097I	Pathogenic	0.574
LRP5	O75197-1.2	A1097K	Pathogenic	0.613
LRP5	O75197-1.2	A1097L	Pathogenic	0.597
LRP5	O75197-1.2	A1097M	Pathogenic	0.692
LRP5	O75197-1.2	A1097N	Pathogenic	0.879
LRP5	O75197-1.2	A1097P	Pathogenic	0.79
LRP5	O75197-1.2	A1097Q	Pathogenic	0.765
LRP5	O75197-1.2	A1097R	Pathogenic	0.605
LRP5	O75197-1.2	A1097S	Neutral	0.307
LRP5	O75197-1.2	A1097T	Pathogenic	0.629
LRP5	O75197-1.2	A1097V	Neutral	0.436
LRP5	O75197-1.2	A1097W	Pathogenic	0.887
LRP5	O75197-1.2	A1097Y	Pathogenic	0.895
LRP5	O75197-1.2	L1098A	Pathogenic	0.883
LRP5	O75197-1.2	L1098C	Pathogenic	0.934
LRP5	O75197-1.2	L1098D	Pathogenic	0.988
LRP5	O75197-1.2	L1098E	Pathogenic	0.97
LRP5	O75197-1.2	L1098F	Pathogenic	0.896
LRP5	O75197-1.2	L1098G	Pathogenic	0.994
LRP5	O75197-1.2	L1098H	Pathogenic	0.985
LRP5	O75197-1.2	L1098I	Neutral	0.482
LRP5	O75197-1.2	L1098K	Pathogenic	0.886
LRP5	O75197-1.2	L1098M	Neutral	0.401
LRP5	O75197-1.2	L1098N	Pathogenic	0.97
LRP5	O75197-1.2	L1098P	Pathogenic	0.991
LRP5	O75197-1.2	L1098Q	Pathogenic	0.939
LRP5	O75197-1.2	L1098R	Pathogenic	0.882
LRP5	O75197-1.2	L1098S	Pathogenic	0.945
LRP5	O75197-1.2	L1098T	Pathogenic	0.882
LRP5	O75197-1.2	L1098V	Pathogenic	0.661
LRP5	O75197-1.2	L1098W	Pathogenic	0.98
LRP5	O75197-1.2	L1098Y	Pathogenic	0.935
LRP5	O75197-1.2	D1099A	Pathogenic	0.997
LRP5	O75197-1.2	D1099C	Pathogenic	0.998
LRP5	O75197-1.2	D1099E	Pathogenic	0.907
LRP5	O75197-1.2	D1099F	Pathogenic	0.996
LRP5	O75197-1.2	D1099G	Pathogenic	0.993
LRP5	O75197-1.2	D1099H	Pathogenic	0.993
LRP5	O75197-1.2	D1099I	Pathogenic	0.996
LRP5	O75197-1.2	D1099K	Pathogenic	0.996
LRP5	O75197-1.2	D1099L	Pathogenic	0.999
LRP5	O75197-1.2	D1099M	Pathogenic	0.998
LRP5	O75197-1.2	D1099N	Pathogenic	0.967
LRP5	O75197-1.2	D1099P	Pathogenic	0.988
LRP5	O75197-1.2	D1099Q	Pathogenic	0.984
LRP5	O75197-1.2	D1099R	Pathogenic	0.999
LRP5	O75197-1.2	D1099S	Pathogenic	0.981
LRP5	O75197-1.2	D1099T	Pathogenic	0.992
LRP5	O75197-1.2	D1099V	Pathogenic	0.998
LRP5	O75197-1.2	D1099W	Pathogenic	0.998
LRP5	O75197-1.2	D1099Y	Pathogenic	0.998
LRP5	O75197-1.2	G1100A	Pathogenic	0.989
LRP5	O75197-1.2	G1100C	Pathogenic	0.999
LRP5	O75197-1.2	G1100D	Pathogenic	0.994
LRP5	O75197-1.2	G1100E	Pathogenic	0.998
LRP5	O75197-1.2	G1100F	Pathogenic	0.998
LRP5	O75197-1.2	G1100H	Pathogenic	0.999
LRP5	O75197-1.2	G1100I	Pathogenic	0.999
LRP5	O75197-1.2	G1100K	Pathogenic	0.998
LRP5	O75197-1.2	G1100L	Pathogenic	1.0
LRP5	O75197-1.2	G1100M	Pathogenic	0.999
LRP5	O75197-1.2	G1100N	Pathogenic	0.985
LRP5	O75197-1.2	G1100P	Pathogenic	0.998
LRP5	O75197-1.2	G1100Q	Pathogenic	0.999
LRP5	O75197-1.2	G1100R	Pathogenic	0.997
LRP5	O75197-1.2	G1100S	Pathogenic	0.991
LRP5	O75197-1.2	G1100T	Pathogenic	0.999
LRP5	O75197-1.2	G1100V	Pathogenic	0.999
LRP5	O75197-1.2	G1100W	Pathogenic	0.992
LRP5	O75197-1.2	G1100Y	Pathogenic	0.999
LRP5	O75197-1.2	T1101A	Pathogenic	0.866
LRP5	O75197-1.2	T1101C	Pathogenic	0.917
LRP5	O75197-1.2	T1101D	Pathogenic	0.895
LRP5	O75197-1.2	T1101E	Pathogenic	0.904
LRP5	O75197-1.2	T1101F	Pathogenic	0.939
LRP5	O75197-1.2	T1101G	Pathogenic	0.98
LRP5	O75197-1.2	T1101H	Pathogenic	0.982
LRP5	O75197-1.2	T1101I	Pathogenic	0.837
LRP5	O75197-1.2	T1101K	Pathogenic	0.868
LRP5	O75197-1.2	T1101L	Pathogenic	0.849
LRP5	O75197-1.2	T1101M	Pathogenic	0.895
LRP5	O75197-1.2	T1101N	Pathogenic	0.765
LRP5	O75197-1.2	T1101P	Pathogenic	0.934
LRP5	O75197-1.2	T1101Q	Pathogenic	0.931
LRP5	O75197-1.2	T1101R	Pathogenic	0.864
LRP5	O75197-1.2	T1101S	Pathogenic	0.633
LRP5	O75197-1.2	T1101V	Pathogenic	0.746
LRP5	O75197-1.2	T1101W	Pathogenic	0.907
LRP5	O75197-1.2	T1101Y	Pathogenic	0.97
LRP5	O75197-1.2	E1102A	Pathogenic	0.979
LRP5	O75197-1.2	E1102C	Pathogenic	0.999
LRP5	O75197-1.2	E1102D	Pathogenic	0.784
LRP5	O75197-1.2	E1102F	Pathogenic	0.992
LRP5	O75197-1.2	E1102G	Pathogenic	0.995
LRP5	O75197-1.2	E1102H	Pathogenic	0.951
LRP5	O75197-1.2	E1102I	Pathogenic	0.992
LRP5	O75197-1.2	E1102K	Pathogenic	0.9
LRP5	O75197-1.2	E1102L	Pathogenic	0.992
LRP5	O75197-1.2	E1102M	Pathogenic	0.985
LRP5	O75197-1.2	E1102N	Pathogenic	0.974
LRP5	O75197-1.2	E1102P	Pathogenic	0.972
LRP5	O75197-1.2	E1102Q	Pathogenic	0.742
LRP5	O75197-1.2	E1102R	Pathogenic	0.963
LRP5	O75197-1.2	E1102S	Pathogenic	0.955
LRP5	O75197-1.2	E1102T	Pathogenic	0.981
LRP5	O75197-1.2	E1102V	Pathogenic	0.986
LRP5	O75197-1.2	E1102W	Pathogenic	0.987
LRP5	O75197-1.2	E1102Y	Pathogenic	0.988
LRP5	O75197-1.2	R1103A	Pathogenic	0.972
LRP5	O75197-1.2	R1103C	Pathogenic	0.994
LRP5	O75197-1.2	R1103D	Pathogenic	0.997
LRP5	O75197-1.2	R1103E	Pathogenic	0.966
LRP5	O75197-1.2	R1103F	Pathogenic	0.99
LRP5	O75197-1.2	R1103G	Pathogenic	0.993
LRP5	O75197-1.2	R1103H	Pathogenic	0.935
LRP5	O75197-1.2	R1103I	Pathogenic	0.989
LRP5	O75197-1.2	R1103K	Pathogenic	0.814
LRP5	O75197-1.2	R1103L	Pathogenic	0.971
LRP5	O75197-1.2	R1103M	Pathogenic	0.943
LRP5	O75197-1.2	R1103N	Pathogenic	0.964
LRP5	O75197-1.2	R1103P	Pathogenic	0.987
LRP5	O75197-1.2	R1103Q	Pathogenic	0.866
LRP5	O75197-1.2	R1103S	Pathogenic	0.979
LRP5	O75197-1.2	R1103T	Pathogenic	0.974
LRP5	O75197-1.2	R1103V	Pathogenic	0.993
LRP5	O75197-1.2	R1103W	Pathogenic	0.984
LRP5	O75197-1.2	R1103Y	Pathogenic	0.985
LRP5	O75197-1.2	E1104A	Pathogenic	0.848
LRP5	O75197-1.2	E1104C	Pathogenic	0.989
LRP5	O75197-1.2	E1104D	Neutral	0.299
LRP5	O75197-1.2	E1104F	Pathogenic	0.934
LRP5	O75197-1.2	E1104G	Pathogenic	0.956
LRP5	O75197-1.2	E1104H	Pathogenic	0.694
LRP5	O75197-1.2	E1104I	Pathogenic	0.934
LRP5	O75197-1.2	E1104K	Pathogenic	0.513
LRP5	O75197-1.2	E1104L	Pathogenic	0.94
LRP5	O75197-1.2	E1104M	Pathogenic	0.886
LRP5	O75197-1.2	E1104N	Pathogenic	0.813
LRP5	O75197-1.2	E1104P	Pathogenic	0.801
LRP5	O75197-1.2	E1104Q	Neutral	0.252
LRP5	O75197-1.2	E1104R	Pathogenic	0.756
LRP5	O75197-1.2	E1104S	Pathogenic	0.716
LRP5	O75197-1.2	E1104T	Pathogenic	0.859
LRP5	O75197-1.2	E1104V	Pathogenic	0.889
LRP5	O75197-1.2	E1104W	Pathogenic	0.899
LRP5	O75197-1.2	E1104Y	Pathogenic	0.906
LRP5	O75197-1.2	V1105A	Neutral	0.361
LRP5	O75197-1.2	V1105C	Pathogenic	0.764
LRP5	O75197-1.2	V1105D	Pathogenic	0.863
LRP5	O75197-1.2	V1105E	Pathogenic	0.704
LRP5	O75197-1.2	V1105F	Pathogenic	0.702
LRP5	O75197-1.2	V1105G	Pathogenic	0.921
LRP5	O75197-1.2	V1105H	Pathogenic	0.934
LRP5	O75197-1.2	V1105I	Neutral	0.027
LRP5	O75197-1.2	V1105K	Pathogenic	0.624
LRP5	O75197-1.2	V1105L	Neutral	0.219
LRP5	O75197-1.2	V1105M	Neutral	0.299
LRP5	O75197-1.2	V1105N	Pathogenic	0.881
LRP5	O75197-1.2	V1105P	Pathogenic	0.887
LRP5	O75197-1.2	V1105Q	Pathogenic	0.774
LRP5	O75197-1.2	V1105R	Pathogenic	0.83
LRP5	O75197-1.2	V1105S	Pathogenic	0.795
LRP5	O75197-1.2	V1105T	Neutral	0.36
LRP5	O75197-1.2	V1105W	Pathogenic	0.932
LRP5	O75197-1.2	V1105Y	Pathogenic	0.756
LRP5	O75197-1.2	L1106A	Pathogenic	0.906
LRP5	O75197-1.2	L1106C	Pathogenic	0.948
LRP5	O75197-1.2	L1106D	Pathogenic	0.991
LRP5	O75197-1.2	L1106E	Pathogenic	0.976
LRP5	O75197-1.2	L1106F	Pathogenic	0.917
LRP5	O75197-1.2	L1106G	Pathogenic	0.995
LRP5	O75197-1.2	L1106H	Pathogenic	0.988
LRP5	O75197-1.2	L1106I	Pathogenic	0.544
LRP5	O75197-1.2	L1106K	Pathogenic	0.908
LRP5	O75197-1.2	L1106M	Neutral	0.462
LRP5	O75197-1.2	L1106N	Pathogenic	0.976
LRP5	O75197-1.2	L1106P	Pathogenic	0.993
LRP5	O75197-1.2	L1106Q	Pathogenic	0.952
LRP5	O75197-1.2	L1106R	Pathogenic	0.906
LRP5	O75197-1.2	L1106S	Pathogenic	0.956
LRP5	O75197-1.2	L1106T	Pathogenic	0.906
LRP5	O75197-1.2	L1106V	Pathogenic	0.714
LRP5	O75197-1.2	L1106W	Pathogenic	0.985
LRP5	O75197-1.2	L1106Y	Pathogenic	0.949
LRP5	O75197-1.2	F1107A	Pathogenic	0.987
LRP5	O75197-1.2	F1107C	Pathogenic	0.993
LRP5	O75197-1.2	F1107D	Pathogenic	0.989
LRP5	O75197-1.2	F1107E	Pathogenic	0.99
LRP5	O75197-1.2	F1107G	Pathogenic	0.994
LRP5	O75197-1.2	F1107H	Pathogenic	0.958
LRP5	O75197-1.2	F1107I	Pathogenic	0.97
LRP5	O75197-1.2	F1107K	Pathogenic	0.987
LRP5	O75197-1.2	F1107L	Pathogenic	0.968
LRP5	O75197-1.2	F1107M	Pathogenic	0.953
LRP5	O75197-1.2	F1107N	Pathogenic	0.991
LRP5	O75197-1.2	F1107P	Pathogenic	0.999
LRP5	O75197-1.2	F1107Q	Pathogenic	0.993
LRP5	O75197-1.2	F1107R	Pathogenic	0.987
LRP5	O75197-1.2	F1107S	Pathogenic	0.982
LRP5	O75197-1.2	F1107T	Pathogenic	0.987
LRP5	O75197-1.2	F1107V	Pathogenic	0.983
LRP5	O75197-1.2	F1107W	Pathogenic	0.875
LRP5	O75197-1.2	F1107Y	Neutral	0.361
LRP5	O75197-1.2	T1108A	Neutral	0.09
LRP5	O75197-1.2	T1108C	Neutral	0.145
LRP5	O75197-1.2	T1108D	Neutral	0.116
LRP5	O75197-1.2	T1108E	Neutral	0.126
LRP5	O75197-1.2	T1108F	Neutral	0.192
LRP5	O75197-1.2	T1108G	Neutral	0.425
LRP5	O75197-1.2	T1108H	Neutral	0.462
LRP5	O75197-1.2	T1108I	Neutral	0.073
LRP5	O75197-1.2	T1108K	Neutral	0.092
LRP5	O75197-1.2	T1108L	Neutral	0.079
LRP5	O75197-1.2	T1108M	Neutral	0.116
LRP5	O75197-1.2	T1108N	Neutral	0.048
LRP5	O75197-1.2	T1108P	Neutral	0.178
LRP5	O75197-1.2	T1108Q	Neutral	0.172
LRP5	O75197-1.2	T1108R	Neutral	0.089
LRP5	O75197-1.2	T1108S	Neutral	0.026
LRP5	O75197-1.2	T1108V	Neutral	0.043
LRP5	O75197-1.2	T1108W	Neutral	0.131
LRP5	O75197-1.2	T1108Y	Neutral	0.33
LRP5	O75197-1.2	T1109A	Neutral	0.425
LRP5	O75197-1.2	T1109C	Pathogenic	0.559
LRP5	O75197-1.2	T1109D	Neutral	0.494
LRP5	O75197-1.2	T1109E	Pathogenic	0.518
LRP5	O75197-1.2	T1109F	Pathogenic	0.639
LRP5	O75197-1.2	T1109G	Pathogenic	0.847
LRP5	O75197-1.2	T1109H	Pathogenic	0.865
LRP5	O75197-1.2	T1109I	Neutral	0.369
LRP5	O75197-1.2	T1109K	Neutral	0.43
LRP5	O75197-1.2	T1109L	Neutral	0.391
LRP5	O75197-1.2	T1109M	Neutral	0.494
LRP5	O75197-1.2	T1109N	Neutral	0.272
LRP5	O75197-1.2	T1109P	Pathogenic	0.618
LRP5	O75197-1.2	T1109Q	Pathogenic	0.608
LRP5	O75197-1.2	T1109R	Neutral	0.421
LRP5	O75197-1.2	T1109S	Neutral	0.165
LRP5	O75197-1.2	T1109V	Neutral	0.251
LRP5	O75197-1.2	T1109W	Pathogenic	0.529
LRP5	O75197-1.2	T1109Y	Pathogenic	0.787
LRP5	O75197-1.2	G1110A	Pathogenic	0.601
LRP5	O75197-1.2	G1110C	Pathogenic	0.957
LRP5	O75197-1.2	G1110D	Pathogenic	0.745
LRP5	O75197-1.2	G1110E	Pathogenic	0.906
LRP5	O75197-1.2	G1110F	Pathogenic	0.91
LRP5	O75197-1.2	G1110H	Pathogenic	0.938
LRP5	O75197-1.2	G1110I	Pathogenic	0.969
LRP5	O75197-1.2	G1110K	Pathogenic	0.872
LRP5	O75197-1.2	G1110L	Pathogenic	0.971
LRP5	O75197-1.2	G1110M	Pathogenic	0.944
LRP5	O75197-1.2	G1110N	Pathogenic	0.525
LRP5	O75197-1.2	G1110P	Pathogenic	0.903
LRP5	O75197-1.2	G1110Q	Pathogenic	0.933
LRP5	O75197-1.2	G1110R	Pathogenic	0.868
LRP5	O75197-1.2	G1110S	Pathogenic	0.655
LRP5	O75197-1.2	G1110T	Pathogenic	0.933
LRP5	O75197-1.2	G1110V	Pathogenic	0.946
LRP5	O75197-1.2	G1110W	Pathogenic	0.678
LRP5	O75197-1.2	G1110Y	Pathogenic	0.955
LRP5	O75197-1.2	L1111A	Pathogenic	0.93
LRP5	O75197-1.2	L1111C	Pathogenic	0.962
LRP5	O75197-1.2	L1111D	Pathogenic	0.993
LRP5	O75197-1.2	L1111E	Pathogenic	0.983
LRP5	O75197-1.2	L1111F	Pathogenic	0.938
LRP5	O75197-1.2	L1111G	Pathogenic	0.996
LRP5	O75197-1.2	L1111H	Pathogenic	0.991
LRP5	O75197-1.2	L1111I	Pathogenic	0.621
LRP5	O75197-1.2	L1111K	Pathogenic	0.932
LRP5	O75197-1.2	L1111M	Pathogenic	0.542
LRP5	O75197-1.2	L1111N	Pathogenic	0.983
LRP5	O75197-1.2	L1111P	Pathogenic	0.995
LRP5	O75197-1.2	L1111Q	Pathogenic	0.965
LRP5	O75197-1.2	L1111R	Pathogenic	0.929
LRP5	O75197-1.2	L1111S	Pathogenic	0.968
LRP5	O75197-1.2	L1111T	Pathogenic	0.93
LRP5	O75197-1.2	L1111V	Pathogenic	0.775
LRP5	O75197-1.2	L1111W	Pathogenic	0.989
LRP5	O75197-1.2	L1111Y	Pathogenic	0.962
LRP5	O75197-1.2	I1112A	Neutral	0.044
LRP5	O75197-1.2	I1112C	Neutral	0.08
LRP5	O75197-1.2	I1112D	Neutral	0.146
LRP5	O75197-1.2	I1112E	Neutral	0.165
LRP5	O75197-1.2	I1112F	Neutral	0.058
LRP5	O75197-1.2	I1112G	Neutral	0.491
LRP5	O75197-1.2	I1112H	Neutral	0.285
LRP5	O75197-1.2	I1112K	Neutral	0.127
LRP5	O75197-1.2	I1112L	Neutral	0.006
LRP5	O75197-1.2	I1112M	Neutral	0.012
LRP5	O75197-1.2	I1112N	Neutral	0.166
LRP5	O75197-1.2	I1112P	Neutral	0.392
LRP5	O75197-1.2	I1112Q	Neutral	0.224
LRP5	O75197-1.2	I1112R	Neutral	0.123
LRP5	O75197-1.2	I1112S	Neutral	0.095
LRP5	O75197-1.2	I1112T	Neutral	0.044
LRP5	O75197-1.2	I1112V	Neutral	0.001
LRP5	O75197-1.2	I1112W	Pathogenic	0.53
LRP5	O75197-1.2	I1112Y	Neutral	0.082
LRP5	O75197-1.2	R1113A	Neutral	0.138
LRP5	O75197-1.2	R1113C	Neutral	0.455
LRP5	O75197-1.2	R1113D	Pathogenic	0.57
LRP5	O75197-1.2	R1113E	Neutral	0.116
LRP5	O75197-1.2	R1113F	Neutral	0.305
LRP5	O75197-1.2	R1113G	Neutral	0.383
LRP5	O75197-1.2	R1113H	Neutral	0.063
LRP5	O75197-1.2	R1113I	Neutral	0.298
LRP5	O75197-1.2	R1113K	Neutral	0.02
LRP5	O75197-1.2	R1113L	Neutral	0.133
LRP5	O75197-1.2	R1113M	Neutral	0.071
LRP5	O75197-1.2	R1113N	Neutral	0.11
LRP5	O75197-1.2	R1113P	Neutral	0.259
LRP5	O75197-1.2	R1113Q	Neutral	0.029
LRP5	O75197-1.2	R1113S	Neutral	0.18
LRP5	O75197-1.2	R1113T	Neutral	0.149
LRP5	O75197-1.2	R1113V	Neutral	0.411
LRP5	O75197-1.2	R1113W	Neutral	0.224
LRP5	O75197-1.2	R1113Y	Neutral	0.234
LRP5	O75197-1.2	P1114A	Pathogenic	0.994
LRP5	O75197-1.2	P1114C	Pathogenic	0.999
LRP5	O75197-1.2	P1114D	Pathogenic	0.986
LRP5	O75197-1.2	P1114E	Pathogenic	0.987
LRP5	O75197-1.2	P1114F	Pathogenic	1.0
LRP5	O75197-1.2	P1114G	Pathogenic	0.998
LRP5	O75197-1.2	P1114H	Pathogenic	0.998
LRP5	O75197-1.2	P1114I	Pathogenic	0.999
LRP5	O75197-1.2	P1114K	Pathogenic	0.982
LRP5	O75197-1.2	P1114L	Pathogenic	0.999
LRP5	O75197-1.2	P1114M	Pathogenic	0.998
LRP5	O75197-1.2	P1114N	Pathogenic	0.996
LRP5	O75197-1.2	P1114Q	Pathogenic	0.991
LRP5	O75197-1.2	P1114R	Pathogenic	0.994
LRP5	O75197-1.2	P1114S	Pathogenic	0.992
LRP5	O75197-1.2	P1114T	Pathogenic	0.994
LRP5	O75197-1.2	P1114V	Pathogenic	0.998
LRP5	O75197-1.2	P1114W	Pathogenic	0.999
LRP5	O75197-1.2	P1114Y	Pathogenic	0.999
LRP5	O75197-1.2	V1115A	Neutral	0.247
LRP5	O75197-1.2	V1115C	Pathogenic	0.653
LRP5	O75197-1.2	V1115D	Pathogenic	0.785
LRP5	O75197-1.2	V1115E	Pathogenic	0.579
LRP5	O75197-1.2	V1115F	Pathogenic	0.577
LRP5	O75197-1.2	V1115G	Pathogenic	0.872
LRP5	O75197-1.2	V1115H	Pathogenic	0.891
LRP5	O75197-1.2	V1115I	Neutral	0.016
LRP5	O75197-1.2	V1115K	Neutral	0.491
LRP5	O75197-1.2	V1115L	Neutral	0.14
LRP5	O75197-1.2	V1115M	Neutral	0.198
LRP5	O75197-1.2	V1115N	Pathogenic	0.811
LRP5	O75197-1.2	V1115P	Pathogenic	0.82
LRP5	O75197-1.2	V1115Q	Pathogenic	0.665
LRP5	O75197-1.2	V1115R	Pathogenic	0.739
LRP5	O75197-1.2	V1115S	Pathogenic	0.693
LRP5	O75197-1.2	V1115T	Neutral	0.246
LRP5	O75197-1.2	V1115W	Pathogenic	0.889
LRP5	O75197-1.2	V1115Y	Pathogenic	0.642
LRP5	O75197-1.2	A1116C	Pathogenic	0.903
LRP5	O75197-1.2	A1116D	Pathogenic	0.983
LRP5	O75197-1.2	A1116E	Pathogenic	0.955
LRP5	O75197-1.2	A1116F	Pathogenic	0.975
LRP5	O75197-1.2	A1116G	Pathogenic	0.928
LRP5	O75197-1.2	A1116H	Pathogenic	0.992
LRP5	O75197-1.2	A1116I	Pathogenic	0.927
LRP5	O75197-1.2	A1116K	Pathogenic	0.937
LRP5	O75197-1.2	A1116L	Pathogenic	0.933
LRP5	O75197-1.2	A1116M	Pathogenic	0.955
LRP5	O75197-1.2	A1116N	Pathogenic	0.986
LRP5	O75197-1.2	A1116P	Pathogenic	0.973
LRP5	O75197-1.2	A1116Q	Pathogenic	0.968
LRP5	O75197-1.2	A1116R	Pathogenic	0.935
LRP5	O75197-1.2	A1116S	Pathogenic	0.807
LRP5	O75197-1.2	A1116T	Pathogenic	0.941
LRP5	O75197-1.2	A1116V	Pathogenic	0.879
LRP5	O75197-1.2	A1116W	Pathogenic	0.987
LRP5	O75197-1.2	A1116Y	Pathogenic	0.988
LRP5	O75197-1.2	L1117A	Pathogenic	0.978
LRP5	O75197-1.2	L1117C	Pathogenic	0.988
LRP5	O75197-1.2	L1117D	Pathogenic	0.998
LRP5	O75197-1.2	L1117E	Pathogenic	0.995
LRP5	O75197-1.2	L1117F	Pathogenic	0.981
LRP5	O75197-1.2	L1117G	Pathogenic	0.999
LRP5	O75197-1.2	L1117H	Pathogenic	0.997
LRP5	O75197-1.2	L1117I	Pathogenic	0.846
LRP5	O75197-1.2	L1117K	Pathogenic	0.979
LRP5	O75197-1.2	L1117M	Pathogenic	0.798
LRP5	O75197-1.2	L1117N	Pathogenic	0.995
LRP5	O75197-1.2	L1117P	Pathogenic	0.998
LRP5	O75197-1.2	L1117Q	Pathogenic	0.989
LRP5	O75197-1.2	L1117R	Pathogenic	0.978
LRP5	O75197-1.2	L1117S	Pathogenic	0.99
LRP5	O75197-1.2	L1117T	Pathogenic	0.978
LRP5	O75197-1.2	L1117V	Pathogenic	0.92
LRP5	O75197-1.2	L1117W	Pathogenic	0.997
LRP5	O75197-1.2	L1117Y	Pathogenic	0.988
LRP5	O75197-1.2	V1118A	Neutral	0.281
LRP5	O75197-1.2	V1118C	Pathogenic	0.692
LRP5	O75197-1.2	V1118D	Pathogenic	0.814
LRP5	O75197-1.2	V1118E	Pathogenic	0.622
LRP5	O75197-1.2	V1118F	Pathogenic	0.62
LRP5	O75197-1.2	V1118G	Pathogenic	0.89
LRP5	O75197-1.2	V1118H	Pathogenic	0.907
LRP5	O75197-1.2	V1118I	Neutral	0.019
LRP5	O75197-1.2	V1118K	Pathogenic	0.535
LRP5	O75197-1.2	V1118L	Neutral	0.163
LRP5	O75197-1.2	V1118M	Neutral	0.228
LRP5	O75197-1.2	V1118N	Pathogenic	0.837
LRP5	O75197-1.2	V1118P	Pathogenic	0.844
LRP5	O75197-1.2	V1118Q	Pathogenic	0.703
LRP5	O75197-1.2	V1118R	Pathogenic	0.772
LRP5	O75197-1.2	V1118S	Pathogenic	0.729
LRP5	O75197-1.2	V1118T	Neutral	0.28
LRP5	O75197-1.2	V1118W	Pathogenic	0.905
LRP5	O75197-1.2	V1118Y	Pathogenic	0.682
LRP5	O75197-1.2	V1119A	Neutral	0.153
LRP5	O75197-1.2	V1119C	Pathogenic	0.508
LRP5	O75197-1.2	V1119D	Pathogenic	0.668
LRP5	O75197-1.2	V1119E	Neutral	0.431
LRP5	O75197-1.2	V1119F	Neutral	0.429
LRP5	O75197-1.2	V1119G	Pathogenic	0.789
LRP5	O75197-1.2	V1119H	Pathogenic	0.819
LRP5	O75197-1.2	V1119I	Neutral	0.009
LRP5	O75197-1.2	V1119K	Neutral	0.346
LRP5	O75197-1.2	V1119L	Neutral	0.082
LRP5	O75197-1.2	V1119M	Neutral	0.12
LRP5	O75197-1.2	V1119N	Pathogenic	0.702
LRP5	O75197-1.2	V1119P	Pathogenic	0.714
LRP5	O75197-1.2	V1119Q	Pathogenic	0.522
LRP5	O75197-1.2	V1119R	Pathogenic	0.609
LRP5	O75197-1.2	V1119S	Pathogenic	0.553
LRP5	O75197-1.2	V1119T	Neutral	0.152
LRP5	O75197-1.2	V1119W	Pathogenic	0.815
LRP5	O75197-1.2	V1119Y	Neutral	0.497
LRP5	O75197-1.2	D1120A	Pathogenic	0.997
LRP5	O75197-1.2	D1120C	Pathogenic	0.998
LRP5	O75197-1.2	D1120E	Pathogenic	0.907
LRP5	O75197-1.2	D1120F	Pathogenic	0.996
LRP5	O75197-1.2	D1120G	Pathogenic	0.993
LRP5	O75197-1.2	D1120H	Pathogenic	0.993
LRP5	O75197-1.2	D1120I	Pathogenic	0.996
LRP5	O75197-1.2	D1120K	Pathogenic	0.996
LRP5	O75197-1.2	D1120L	Pathogenic	0.999
LRP5	O75197-1.2	D1120M	Pathogenic	0.998
LRP5	O75197-1.2	D1120N	Pathogenic	0.967
LRP5	O75197-1.2	D1120P	Pathogenic	0.988
LRP5	O75197-1.2	D1120Q	Pathogenic	0.984
LRP5	O75197-1.2	D1120R	Pathogenic	0.999
LRP5	O75197-1.2	D1120S	Pathogenic	0.981
LRP5	O75197-1.2	D1120T	Pathogenic	0.992
LRP5	O75197-1.2	D1120V	Pathogenic	0.998
LRP5	O75197-1.2	D1120W	Pathogenic	0.998
LRP5	O75197-1.2	D1120Y	Pathogenic	0.998
LRP5	O75197-1.2	N1121A	Pathogenic	0.662
LRP5	O75197-1.2	N1121C	Pathogenic	0.771
LRP5	O75197-1.2	N1121D	Neutral	0.123
LRP5	O75197-1.2	N1121E	Neutral	0.322
LRP5	O75197-1.2	N1121F	Pathogenic	0.61
LRP5	O75197-1.2	N1121G	Neutral	0.213
LRP5	O75197-1.2	N1121H	Neutral	0.076
LRP5	O75197-1.2	N1121I	Pathogenic	0.611
LRP5	O75197-1.2	N1121K	Neutral	0.249
LRP5	O75197-1.2	N1121L	Pathogenic	0.632
LRP5	O75197-1.2	N1121M	Neutral	0.462
LRP5	O75197-1.2	N1121P	Pathogenic	0.585
LRP5	O75197-1.2	N1121Q	Neutral	0.257
LRP5	O75197-1.2	N1121R	Neutral	0.243
LRP5	O75197-1.2	N1121S	Neutral	0.087
LRP5	O75197-1.2	N1121T	Neutral	0.188
LRP5	O75197-1.2	N1121V	Pathogenic	0.732
LRP5	O75197-1.2	N1121W	Pathogenic	0.75
LRP5	O75197-1.2	N1121Y	Pathogenic	0.516
LRP5	O75197-1.2	T1122A	Neutral	0.001
LRP5	O75197-1.2	T1122C	Neutral	0.003
LRP5	O75197-1.2	T1122D	Neutral	0.002
LRP5	O75197-1.2	T1122E	Neutral	0.002
LRP5	O75197-1.2	T1122F	Neutral	0.004
LRP5	O75197-1.2	T1122G	Neutral	0.011
LRP5	O75197-1.2	T1122H	Neutral	0.013
LRP5	O75197-1.2	T1122I	Neutral	0.001
LRP5	O75197-1.2	T1122K	Neutral	0.002
LRP5	O75197-1.2	T1122L	Neutral	0.001
LRP5	O75197-1.2	T1122M	Neutral	0.002
LRP5	O75197-1.2	T1122N	Neutral	0.001
LRP5	O75197-1.2	T1122P	Neutral	0.003
LRP5	O75197-1.2	T1122Q	Neutral	0.003
LRP5	O75197-1.2	T1122R	Neutral	0.001
LRP5	O75197-1.2	T1122S	Neutral	0.0
LRP5	O75197-1.2	T1122V	Neutral	0.001
LRP5	O75197-1.2	T1122W	Neutral	0.002
LRP5	O75197-1.2	T1122Y	Neutral	0.007
LRP5	O75197-1.2	L1123A	Neutral	0.367
LRP5	O75197-1.2	L1123C	Pathogenic	0.522
LRP5	O75197-1.2	L1123D	Pathogenic	0.866
LRP5	O75197-1.2	L1123E	Pathogenic	0.711
LRP5	O75197-1.2	L1123F	Neutral	0.397
LRP5	O75197-1.2	L1123G	Pathogenic	0.923
LRP5	O75197-1.2	L1123H	Pathogenic	0.833
LRP5	O75197-1.2	L1123I	Neutral	0.067
LRP5	O75197-1.2	L1123K	Neutral	0.373
LRP5	O75197-1.2	L1123M	Neutral	0.049
LRP5	O75197-1.2	L1123N	Pathogenic	0.714
LRP5	O75197-1.2	L1123P	Pathogenic	0.889
LRP5	O75197-1.2	L1123Q	Pathogenic	0.543
LRP5	O75197-1.2	L1123R	Neutral	0.365
LRP5	O75197-1.2	L1123S	Pathogenic	0.567
LRP5	O75197-1.2	L1123T	Neutral	0.366
LRP5	O75197-1.2	L1123V	Neutral	0.131
LRP5	O75197-1.2	L1123W	Pathogenic	0.794
LRP5	O75197-1.2	L1123Y	Pathogenic	0.526
LRP5	O75197-1.2	G1124A	Pathogenic	0.784
LRP5	O75197-1.2	G1124C	Pathogenic	0.982
LRP5	O75197-1.2	G1124D	Pathogenic	0.875
LRP5	O75197-1.2	G1124E	Pathogenic	0.959
LRP5	O75197-1.2	G1124F	Pathogenic	0.961
LRP5	O75197-1.2	G1124H	Pathogenic	0.973
LRP5	O75197-1.2	G1124I	Pathogenic	0.987
LRP5	O75197-1.2	G1124K	Pathogenic	0.942
LRP5	O75197-1.2	G1124L	Pathogenic	0.988
LRP5	O75197-1.2	G1124M	Pathogenic	0.976
LRP5	O75197-1.2	G1124N	Pathogenic	0.727
LRP5	O75197-1.2	G1124P	Pathogenic	0.957
LRP5	O75197-1.2	G1124Q	Pathogenic	0.971
LRP5	O75197-1.2	G1124R	Pathogenic	0.941
LRP5	O75197-1.2	G1124S	Pathogenic	0.821
LRP5	O75197-1.2	G1124T	Pathogenic	0.971
LRP5	O75197-1.2	G1124V	Pathogenic	0.977
LRP5	O75197-1.2	G1124W	Pathogenic	0.835
LRP5	O75197-1.2	G1124Y	Pathogenic	0.981
LRP5	O75197-1.2	K1125A	Pathogenic	0.915
LRP5	O75197-1.2	K1125C	Pathogenic	0.983
LRP5	O75197-1.2	K1125D	Pathogenic	0.967
LRP5	O75197-1.2	K1125E	Pathogenic	0.744
LRP5	O75197-1.2	K1125F	Pathogenic	0.967
LRP5	O75197-1.2	K1125G	Pathogenic	0.977
LRP5	O75197-1.2	K1125H	Pathogenic	0.932
LRP5	O75197-1.2	K1125I	Pathogenic	0.966
LRP5	O75197-1.2	K1125L	Pathogenic	0.912
LRP5	O75197-1.2	K1125M	Pathogenic	0.838
LRP5	O75197-1.2	K1125N	Pathogenic	0.893
LRP5	O75197-1.2	K1125P	Pathogenic	0.886
LRP5	O75197-1.2	K1125Q	Pathogenic	0.668
LRP5	O75197-1.2	K1125R	Pathogenic	0.569
LRP5	O75197-1.2	K1125S	Pathogenic	0.83
LRP5	O75197-1.2	K1125T	Pathogenic	0.922
LRP5	O75197-1.2	K1125V	Pathogenic	0.939
LRP5	O75197-1.2	K1125W	Pathogenic	0.949
LRP5	O75197-1.2	K1125Y	Pathogenic	0.953
LRP5	O75197-1.2	L1126A	Pathogenic	0.937
LRP5	O75197-1.2	L1126C	Pathogenic	0.966
LRP5	O75197-1.2	L1126D	Pathogenic	0.994
LRP5	O75197-1.2	L1126E	Pathogenic	0.985
LRP5	O75197-1.2	L1126F	Pathogenic	0.944
LRP5	O75197-1.2	L1126G	Pathogenic	0.997
LRP5	O75197-1.2	L1126H	Pathogenic	0.992
LRP5	O75197-1.2	L1126I	Pathogenic	0.649
LRP5	O75197-1.2	L1126K	Pathogenic	0.939
LRP5	O75197-1.2	L1126M	Pathogenic	0.571
LRP5	O75197-1.2	L1126N	Pathogenic	0.985
LRP5	O75197-1.2	L1126P	Pathogenic	0.995
LRP5	O75197-1.2	L1126Q	Pathogenic	0.968
LRP5	O75197-1.2	L1126R	Pathogenic	0.937
LRP5	O75197-1.2	L1126S	Pathogenic	0.971
LRP5	O75197-1.2	L1126T	Pathogenic	0.937
LRP5	O75197-1.2	L1126V	Pathogenic	0.795
LRP5	O75197-1.2	L1126W	Pathogenic	0.99
LRP5	O75197-1.2	L1126Y	Pathogenic	0.966
LRP5	O75197-1.2	F1127A	Pathogenic	0.993
LRP5	O75197-1.2	F1127C	Pathogenic	0.996
LRP5	O75197-1.2	F1127D	Pathogenic	0.994
LRP5	O75197-1.2	F1127E	Pathogenic	0.995
LRP5	O75197-1.2	F1127G	Pathogenic	0.997
LRP5	O75197-1.2	F1127H	Pathogenic	0.977
LRP5	O75197-1.2	F1127I	Pathogenic	0.984
LRP5	O75197-1.2	F1127K	Pathogenic	0.993
LRP5	O75197-1.2	F1127L	Pathogenic	0.983
LRP5	O75197-1.2	F1127M	Pathogenic	0.974
LRP5	O75197-1.2	F1127N	Pathogenic	0.995
LRP5	O75197-1.2	F1127P	Pathogenic	0.999
LRP5	O75197-1.2	F1127Q	Pathogenic	0.997
LRP5	O75197-1.2	F1127R	Pathogenic	0.993
LRP5	O75197-1.2	F1127S	Pathogenic	0.99
LRP5	O75197-1.2	F1127T	Pathogenic	0.993
LRP5	O75197-1.2	F1127V	Pathogenic	0.991
LRP5	O75197-1.2	F1127W	Pathogenic	0.929
LRP5	O75197-1.2	F1127Y	Pathogenic	0.515
LRP5	O75197-1.2	W1128A	Pathogenic	1.0
LRP5	O75197-1.2	W1128C	Pathogenic	0.999
LRP5	O75197-1.2	W1128D	Pathogenic	1.0
LRP5	O75197-1.2	W1128E	Pathogenic	0.999
LRP5	O75197-1.2	W1128F	Pathogenic	0.991
LRP5	O75197-1.2	W1128G	Pathogenic	0.998
LRP5	O75197-1.2	W1128H	Pathogenic	0.999
LRP5	O75197-1.2	W1128I	Pathogenic	1.0
LRP5	O75197-1.2	W1128K	Pathogenic	0.999
LRP5	O75197-1.2	W1128L	Pathogenic	1.0
LRP5	O75197-1.2	W1128M	Pathogenic	0.998
LRP5	O75197-1.2	W1128N	Pathogenic	1.0
LRP5	O75197-1.2	W1128P	Pathogenic	1.0
LRP5	O75197-1.2	W1128Q	Pathogenic	0.998
LRP5	O75197-1.2	W1128R	Pathogenic	0.999
LRP5	O75197-1.2	W1128S	Pathogenic	0.999
LRP5	O75197-1.2	W1128T	Pathogenic	0.999
LRP5	O75197-1.2	W1128V	Pathogenic	1.0
LRP5	O75197-1.2	W1128Y	Pathogenic	0.945
LRP5	O75197-1.2	V1129A	Neutral	0.29
LRP5	O75197-1.2	V1129C	Pathogenic	0.7
LRP5	O75197-1.2	V1129D	Pathogenic	0.82
LRP5	O75197-1.2	V1129E	Pathogenic	0.631
LRP5	O75197-1.2	V1129F	Pathogenic	0.63
LRP5	O75197-1.2	V1129G	Pathogenic	0.894
LRP5	O75197-1.2	V1129H	Pathogenic	0.911
LRP5	O75197-1.2	V1129I	Neutral	0.02
LRP5	O75197-1.2	V1129K	Pathogenic	0.545
LRP5	O75197-1.2	V1129L	Neutral	0.168
LRP5	O75197-1.2	V1129M	Neutral	0.235
LRP5	O75197-1.2	V1129N	Pathogenic	0.842
LRP5	O75197-1.2	V1129P	Pathogenic	0.85
LRP5	O75197-1.2	V1129Q	Pathogenic	0.712
LRP5	O75197-1.2	V1129R	Pathogenic	0.779
LRP5	O75197-1.2	V1129S	Pathogenic	0.737
LRP5	O75197-1.2	V1129T	Neutral	0.289
LRP5	O75197-1.2	V1129W	Pathogenic	0.909
LRP5	O75197-1.2	V1129Y	Pathogenic	0.691
LRP5	O75197-1.2	D1130A	Pathogenic	0.98
LRP5	O75197-1.2	D1130C	Pathogenic	0.988
LRP5	O75197-1.2	D1130E	Pathogenic	0.579
LRP5	O75197-1.2	D1130F	Pathogenic	0.975
LRP5	O75197-1.2	D1130G	Pathogenic	0.955
LRP5	O75197-1.2	D1130H	Pathogenic	0.95
LRP5	O75197-1.2	D1130I	Pathogenic	0.975
LRP5	O75197-1.2	D1130K	Pathogenic	0.972
LRP5	O75197-1.2	D1130L	Pathogenic	0.992
LRP5	O75197-1.2	D1130M	Pathogenic	0.985
LRP5	O75197-1.2	D1130N	Pathogenic	0.805
LRP5	O75197-1.2	D1130P	Pathogenic	0.922
LRP5	O75197-1.2	D1130Q	Pathogenic	0.897
LRP5	O75197-1.2	D1130R	Pathogenic	0.99
LRP5	O75197-1.2	D1130S	Pathogenic	0.881
LRP5	O75197-1.2	D1130T	Pathogenic	0.947
LRP5	O75197-1.2	D1130V	Pathogenic	0.986
LRP5	O75197-1.2	D1130W	Pathogenic	0.987
LRP5	O75197-1.2	D1130Y	Pathogenic	0.988
LRP5	O75197-1.2	A1131C	Neutral	0.101
LRP5	O75197-1.2	A1131D	Neutral	0.417
LRP5	O75197-1.2	A1131E	Neutral	0.205
LRP5	O75197-1.2	A1131F	Neutral	0.318
LRP5	O75197-1.2	A1131G	Neutral	0.134
LRP5	O75197-1.2	A1131H	Pathogenic	0.606
LRP5	O75197-1.2	A1131I	Neutral	0.133
LRP5	O75197-1.2	A1131K	Neutral	0.153
LRP5	O75197-1.2	A1131L	Neutral	0.144
LRP5	O75197-1.2	A1131M	Neutral	0.204
LRP5	O75197-1.2	A1131N	Neutral	0.452
LRP5	O75197-1.2	A1131P	Neutral	0.3
LRP5	O75197-1.2	A1131Q	Neutral	0.271
LRP5	O75197-1.2	A1131R	Neutral	0.148
LRP5	O75197-1.2	A1131S	Neutral	0.048
LRP5	O75197-1.2	A1131T	Neutral	0.162
LRP5	O75197-1.2	A1131V	Neutral	0.081
LRP5	O75197-1.2	A1131W	Neutral	0.472
LRP5	O75197-1.2	A1131Y	Neutral	0.492
LRP5	O75197-1.2	D1132A	Pathogenic	0.864
LRP5	O75197-1.2	D1132C	Pathogenic	0.916
LRP5	O75197-1.2	D1132E	Neutral	0.149
LRP5	O75197-1.2	D1132F	Pathogenic	0.833
LRP5	O75197-1.2	D1132G	Pathogenic	0.728
LRP5	O75197-1.2	D1132H	Pathogenic	0.709
LRP5	O75197-1.2	D1132I	Pathogenic	0.834
LRP5	O75197-1.2	D1132K	Pathogenic	0.814
LRP5	O75197-1.2	D1132L	Pathogenic	0.944
LRP5	O75197-1.2	D1132M	Pathogenic	0.893
LRP5	O75197-1.2	D1132N	Neutral	0.344
LRP5	O75197-1.2	D1132P	Pathogenic	0.601
LRP5	O75197-1.2	D1132Q	Pathogenic	0.525
LRP5	O75197-1.2	D1132R	Pathogenic	0.928
LRP5	O75197-1.2	D1132S	Neutral	0.486
LRP5	O75197-1.2	D1132T	Pathogenic	0.694
LRP5	O75197-1.2	D1132V	Pathogenic	0.897
LRP5	O75197-1.2	D1132W	Pathogenic	0.906
LRP5	O75197-1.2	D1132Y	Pathogenic	0.912
LRP5	O75197-1.2	L1133A	Pathogenic	0.837
LRP5	O75197-1.2	L1133C	Pathogenic	0.906
LRP5	O75197-1.2	L1133D	Pathogenic	0.983
LRP5	O75197-1.2	L1133E	Pathogenic	0.956
LRP5	O75197-1.2	L1133F	Pathogenic	0.853
LRP5	O75197-1.2	L1133G	Pathogenic	0.991
LRP5	O75197-1.2	L1133H	Pathogenic	0.978
LRP5	O75197-1.2	L1133I	Neutral	0.387
LRP5	O75197-1.2	L1133K	Pathogenic	0.84
LRP5	O75197-1.2	L1133M	Neutral	0.313
LRP5	O75197-1.2	L1133N	Pathogenic	0.957
LRP5	O75197-1.2	L1133P	Pathogenic	0.986
LRP5	O75197-1.2	L1133Q	Pathogenic	0.913
LRP5	O75197-1.2	L1133R	Pathogenic	0.835
LRP5	O75197-1.2	L1133S	Pathogenic	0.92
LRP5	O75197-1.2	L1133T	Pathogenic	0.836
LRP5	O75197-1.2	L1133V	Pathogenic	0.57
LRP5	O75197-1.2	L1133W	Pathogenic	0.971
LRP5	O75197-1.2	L1133Y	Pathogenic	0.907
LRP5	O75197-1.2	K1134A	Pathogenic	0.688
LRP5	O75197-1.2	K1134C	Pathogenic	0.92
LRP5	O75197-1.2	K1134D	Pathogenic	0.857
LRP5	O75197-1.2	K1134E	Neutral	0.373
LRP5	O75197-1.2	K1134F	Pathogenic	0.858
LRP5	O75197-1.2	K1134G	Pathogenic	0.896
LRP5	O75197-1.2	K1134H	Pathogenic	0.737
LRP5	O75197-1.2	K1134I	Pathogenic	0.854
LRP5	O75197-1.2	K1134L	Pathogenic	0.679
LRP5	O75197-1.2	K1134M	Pathogenic	0.514
LRP5	O75197-1.2	K1134N	Pathogenic	0.631
LRP5	O75197-1.2	K1134P	Pathogenic	0.613
LRP5	O75197-1.2	K1134Q	Neutral	0.292
LRP5	O75197-1.2	K1134R	Neutral	0.212
LRP5	O75197-1.2	K1134S	Neutral	0.499
LRP5	O75197-1.2	K1134T	Pathogenic	0.707
LRP5	O75197-1.2	K1134V	Pathogenic	0.76
LRP5	O75197-1.2	K1134W	Pathogenic	0.793
LRP5	O75197-1.2	K1134Y	Pathogenic	0.805
LRP5	O75197-1.2	R1135A	Pathogenic	0.852
LRP5	O75197-1.2	R1135C	Pathogenic	0.968
LRP5	O75197-1.2	R1135D	Pathogenic	0.98
LRP5	O75197-1.2	R1135E	Pathogenic	0.826
LRP5	O75197-1.2	R1135F	Pathogenic	0.941
LRP5	O75197-1.2	R1135G	Pathogenic	0.957
LRP5	O75197-1.2	R1135H	Pathogenic	0.707
LRP5	O75197-1.2	R1135I	Pathogenic	0.939
LRP5	O75197-1.2	R1135K	Neutral	0.422
LRP5	O75197-1.2	R1135L	Pathogenic	0.847
LRP5	O75197-1.2	R1135M	Pathogenic	0.735
LRP5	O75197-1.2	R1135N	Pathogenic	0.818
LRP5	O75197-1.2	R1135P	Pathogenic	0.927
LRP5	O75197-1.2	R1135Q	Pathogenic	0.519
LRP5	O75197-1.2	R1135S	Pathogenic	0.888
LRP5	O75197-1.2	R1135T	Pathogenic	0.863
LRP5	O75197-1.2	R1135V	Pathogenic	0.962
LRP5	O75197-1.2	R1135W	Pathogenic	0.913
LRP5	O75197-1.2	R1135Y	Pathogenic	0.917
LRP5	O75197-1.2	I1136A	Pathogenic	0.987
LRP5	O75197-1.2	I1136C	Pathogenic	0.993
LRP5	O75197-1.2	I1136D	Pathogenic	0.996
LRP5	O75197-1.2	I1136E	Pathogenic	0.997
LRP5	O75197-1.2	I1136F	Pathogenic	0.99
LRP5	O75197-1.2	I1136G	Pathogenic	0.999
LRP5	O75197-1.2	I1136H	Pathogenic	0.998
LRP5	O75197-1.2	I1136K	Pathogenic	0.996
LRP5	O75197-1.2	I1136L	Pathogenic	0.911
LRP5	O75197-1.2	I1136M	Pathogenic	0.954
LRP5	O75197-1.2	I1136N	Pathogenic	0.997
LRP5	O75197-1.2	I1136P	Pathogenic	0.999
LRP5	O75197-1.2	I1136Q	Pathogenic	0.998
LRP5	O75197-1.2	I1136R	Pathogenic	0.996
LRP5	O75197-1.2	I1136S	Pathogenic	0.994
LRP5	O75197-1.2	I1136T	Pathogenic	0.987
LRP5	O75197-1.2	I1136V	Pathogenic	0.68
LRP5	O75197-1.2	I1136W	Pathogenic	0.999
LRP5	O75197-1.2	I1136Y	Pathogenic	0.993
LRP5	O75197-1.2	E1137A	Pathogenic	0.994
LRP5	O75197-1.2	E1137C	Pathogenic	1.0
LRP5	O75197-1.2	E1137D	Pathogenic	0.93
LRP5	O75197-1.2	E1137F	Pathogenic	0.998
LRP5	O75197-1.2	E1137G	Pathogenic	0.999
LRP5	O75197-1.2	E1137H	Pathogenic	0.986
LRP5	O75197-1.2	E1137I	Pathogenic	0.998
LRP5	O75197-1.2	E1137K	Pathogenic	0.97
LRP5	O75197-1.2	E1137L	Pathogenic	0.998
LRP5	O75197-1.2	E1137M	Pathogenic	0.996
LRP5	O75197-1.2	E1137N	Pathogenic	0.993
LRP5	O75197-1.2	E1137P	Pathogenic	0.992
LRP5	O75197-1.2	E1137Q	Pathogenic	0.913
LRP5	O75197-1.2	E1137R	Pathogenic	0.99
LRP5	O75197-1.2	E1137S	Pathogenic	0.987
LRP5	O75197-1.2	E1137T	Pathogenic	0.995
LRP5	O75197-1.2	E1137V	Pathogenic	0.996
LRP5	O75197-1.2	E1137W	Pathogenic	0.996
LRP5	O75197-1.2	E1137Y	Pathogenic	0.997
LRP5	O75197-1.2	S1138A	Pathogenic	0.511
LRP5	O75197-1.2	S1138C	Pathogenic	0.84
LRP5	O75197-1.2	S1138D	Pathogenic	0.688
LRP5	O75197-1.2	S1138E	Pathogenic	0.707
LRP5	O75197-1.2	S1138F	Pathogenic	0.877
LRP5	O75197-1.2	S1138G	Pathogenic	0.803
LRP5	O75197-1.2	S1138H	Pathogenic	0.914
LRP5	O75197-1.2	S1138I	Pathogenic	0.878
LRP5	O75197-1.2	S1138K	Pathogenic	0.628
LRP5	O75197-1.2	S1138L	Pathogenic	0.887
LRP5	O75197-1.2	S1138M	Pathogenic	0.798
LRP5	O75197-1.2	S1138N	Neutral	0.455
LRP5	O75197-1.2	S1138P	Pathogenic	0.868
LRP5	O75197-1.2	S1138Q	Pathogenic	0.776
LRP5	O75197-1.2	S1138R	Pathogenic	0.832
LRP5	O75197-1.2	S1138T	Pathogenic	0.517
LRP5	O75197-1.2	S1138V	Pathogenic	0.926
LRP5	O75197-1.2	S1138W	Pathogenic	0.932
LRP5	O75197-1.2	S1138Y	Pathogenic	0.937
LRP5	O75197-1.2	C1139A	Neutral	0.485
LRP5	O75197-1.2	C1139D	Pathogenic	0.912
LRP5	O75197-1.2	C1139E	Pathogenic	0.972
LRP5	O75197-1.2	C1139F	Pathogenic	0.881
LRP5	O75197-1.2	C1139G	Pathogenic	0.951
LRP5	O75197-1.2	C1139H	Pathogenic	0.957
LRP5	O75197-1.2	C1139I	Pathogenic	0.709
LRP5	O75197-1.2	C1139K	Pathogenic	0.888
LRP5	O75197-1.2	C1139L	Pathogenic	0.727
LRP5	O75197-1.2	C1139M	Pathogenic	0.802
LRP5	O75197-1.2	C1139N	Pathogenic	0.923
LRP5	O75197-1.2	C1139P	Pathogenic	0.975
LRP5	O75197-1.2	C1139Q	Pathogenic	0.942
LRP5	O75197-1.2	C1139R	Pathogenic	0.884
LRP5	O75197-1.2	C1139S	Pathogenic	0.68
LRP5	O75197-1.2	C1139T	Pathogenic	0.736
LRP5	O75197-1.2	C1139V	Pathogenic	0.809
LRP5	O75197-1.2	C1139W	Pathogenic	0.823
LRP5	O75197-1.2	C1139Y	Pathogenic	0.936
LRP5	O75197-1.2	D1140A	Pathogenic	0.988
LRP5	O75197-1.2	D1140C	Pathogenic	0.993
LRP5	O75197-1.2	D1140E	Pathogenic	0.702
LRP5	O75197-1.2	D1140F	Pathogenic	0.985
LRP5	O75197-1.2	D1140G	Pathogenic	0.973
LRP5	O75197-1.2	D1140H	Pathogenic	0.97
LRP5	O75197-1.2	D1140I	Pathogenic	0.985
LRP5	O75197-1.2	D1140K	Pathogenic	0.983
LRP5	O75197-1.2	D1140L	Pathogenic	0.996
LRP5	O75197-1.2	D1140M	Pathogenic	0.991
LRP5	O75197-1.2	D1140N	Pathogenic	0.876
LRP5	O75197-1.2	D1140P	Pathogenic	0.953
LRP5	O75197-1.2	D1140Q	Pathogenic	0.937
LRP5	O75197-1.2	D1140R	Pathogenic	0.994
LRP5	O75197-1.2	D1140S	Pathogenic	0.927
LRP5	O75197-1.2	D1140T	Pathogenic	0.968
LRP5	O75197-1.2	D1140V	Pathogenic	0.992
LRP5	O75197-1.2	D1140W	Pathogenic	0.992
LRP5	O75197-1.2	D1140Y	Pathogenic	0.993
LRP5	O75197-1.2	L1141A	Pathogenic	0.925
LRP5	O75197-1.2	L1141C	Pathogenic	0.959
LRP5	O75197-1.2	L1141D	Pathogenic	0.993
LRP5	O75197-1.2	L1141E	Pathogenic	0.981
LRP5	O75197-1.2	L1141F	Pathogenic	0.934
LRP5	O75197-1.2	L1141G	Pathogenic	0.996
LRP5	O75197-1.2	L1141H	Pathogenic	0.991
LRP5	O75197-1.2	L1141I	Pathogenic	0.604
LRP5	O75197-1.2	L1141K	Pathogenic	0.927
LRP5	O75197-1.2	L1141M	Pathogenic	0.524
LRP5	O75197-1.2	L1141N	Pathogenic	0.982
LRP5	O75197-1.2	L1141P	Pathogenic	0.994
LRP5	O75197-1.2	L1141Q	Pathogenic	0.962
LRP5	O75197-1.2	L1141R	Pathogenic	0.925
LRP5	O75197-1.2	L1141S	Pathogenic	0.965
LRP5	O75197-1.2	L1141T	Pathogenic	0.925
LRP5	O75197-1.2	L1141V	Pathogenic	0.762
LRP5	O75197-1.2	L1141W	Pathogenic	0.988
LRP5	O75197-1.2	L1141Y	Pathogenic	0.959
LRP5	O75197-1.2	S1142A	Neutral	0.152
LRP5	O75197-1.2	S1142C	Neutral	0.473
LRP5	O75197-1.2	S1142D	Neutral	0.274
LRP5	O75197-1.2	S1142E	Neutral	0.292
LRP5	O75197-1.2	S1142F	Pathogenic	0.551
LRP5	O75197-1.2	S1142G	Neutral	0.41
LRP5	O75197-1.2	S1142H	Pathogenic	0.646
LRP5	O75197-1.2	S1142I	Pathogenic	0.552
LRP5	O75197-1.2	S1142K	Neutral	0.224
LRP5	O75197-1.2	S1142L	Pathogenic	0.574
LRP5	O75197-1.2	S1142M	Neutral	0.403
LRP5	O75197-1.2	S1142N	Neutral	0.125
LRP5	O75197-1.2	S1142P	Pathogenic	0.53
LRP5	O75197-1.2	S1142Q	Neutral	0.373
LRP5	O75197-1.2	S1142R	Neutral	0.459
LRP5	O75197-1.2	S1142T	Neutral	0.155
LRP5	O75197-1.2	S1142V	Pathogenic	0.682
LRP5	O75197-1.2	S1142W	Pathogenic	0.702
LRP5	O75197-1.2	S1142Y	Pathogenic	0.718
LRP5	O75197-1.2	G1143A	Pathogenic	0.98
LRP5	O75197-1.2	G1143C	Pathogenic	0.999
LRP5	O75197-1.2	G1143D	Pathogenic	0.99
LRP5	O75197-1.2	G1143E	Pathogenic	0.997
LRP5	O75197-1.2	G1143F	Pathogenic	0.997
LRP5	O75197-1.2	G1143H	Pathogenic	0.998
LRP5	O75197-1.2	G1143I	Pathogenic	0.999
LRP5	O75197-1.2	G1143K	Pathogenic	0.996
LRP5	O75197-1.2	G1143L	Pathogenic	0.999
LRP5	O75197-1.2	G1143M	Pathogenic	0.998
LRP5	O75197-1.2	G1143N	Pathogenic	0.974
LRP5	O75197-1.2	G1143P	Pathogenic	0.997
LRP5	O75197-1.2	G1143Q	Pathogenic	0.998
LRP5	O75197-1.2	G1143R	Pathogenic	0.995
LRP5	O75197-1.2	G1143S	Pathogenic	0.984
LRP5	O75197-1.2	G1143T	Pathogenic	0.998
LRP5	O75197-1.2	G1143V	Pathogenic	0.998
LRP5	O75197-1.2	G1143W	Pathogenic	0.986
LRP5	O75197-1.2	G1143Y	Pathogenic	0.999
LRP5	O75197-1.2	A1144C	Pathogenic	0.726
LRP5	O75197-1.2	A1144D	Pathogenic	0.944
LRP5	O75197-1.2	A1144E	Pathogenic	0.859
LRP5	O75197-1.2	A1144F	Pathogenic	0.917
LRP5	O75197-1.2	A1144G	Pathogenic	0.786
LRP5	O75197-1.2	A1144H	Pathogenic	0.973
LRP5	O75197-1.2	A1144I	Pathogenic	0.784
LRP5	O75197-1.2	A1144K	Pathogenic	0.81
LRP5	O75197-1.2	A1144L	Pathogenic	0.8
LRP5	O75197-1.2	A1144M	Pathogenic	0.859
LRP5	O75197-1.2	A1144N	Pathogenic	0.951
LRP5	O75197-1.2	A1144P	Pathogenic	0.91
LRP5	O75197-1.2	A1144Q	Pathogenic	0.898
LRP5	O75197-1.2	A1144R	Pathogenic	0.805
LRP5	O75197-1.2	A1144S	Pathogenic	0.544
LRP5	O75197-1.2	A1144T	Pathogenic	0.821
LRP5	O75197-1.2	A1144V	Pathogenic	0.676
LRP5	O75197-1.2	A1144W	Pathogenic	0.955
LRP5	O75197-1.2	A1144Y	Pathogenic	0.958
LRP5	O75197-1.2	N1145A	Pathogenic	0.992
LRP5	O75197-1.2	N1145C	Pathogenic	0.995
LRP5	O75197-1.2	N1145D	Pathogenic	0.902
LRP5	O75197-1.2	N1145E	Pathogenic	0.969
LRP5	O75197-1.2	N1145F	Pathogenic	0.99
LRP5	O75197-1.2	N1145G	Pathogenic	0.947
LRP5	O75197-1.2	N1145H	Pathogenic	0.844
LRP5	O75197-1.2	N1145I	Pathogenic	0.99
LRP5	O75197-1.2	N1145K	Pathogenic	0.956
LRP5	O75197-1.2	N1145L	Pathogenic	0.991
LRP5	O75197-1.2	N1145M	Pathogenic	0.983
LRP5	O75197-1.2	N1145P	Pathogenic	0.989
LRP5	O75197-1.2	N1145Q	Pathogenic	0.958
LRP5	O75197-1.2	N1145R	Pathogenic	0.955
LRP5	O75197-1.2	N1145S	Pathogenic	0.863
LRP5	O75197-1.2	N1145T	Pathogenic	0.938
LRP5	O75197-1.2	N1145V	Pathogenic	0.994
LRP5	O75197-1.2	N1145W	Pathogenic	0.995
LRP5	O75197-1.2	N1145Y	Pathogenic	0.986
LRP5	O75197-1.2	R1146A	Pathogenic	0.988
LRP5	O75197-1.2	R1146C	Pathogenic	0.998
LRP5	O75197-1.2	R1146D	Pathogenic	0.999
LRP5	O75197-1.2	R1146E	Pathogenic	0.985
LRP5	O75197-1.2	R1146F	Pathogenic	0.995
LRP5	O75197-1.2	R1146G	Pathogenic	0.997
LRP5	O75197-1.2	R1146H	Pathogenic	0.971
LRP5	O75197-1.2	R1146I	Pathogenic	0.995
LRP5	O75197-1.2	R1146K	Pathogenic	0.911
LRP5	O75197-1.2	R1146L	Pathogenic	0.987
LRP5	O75197-1.2	R1146M	Pathogenic	0.975
LRP5	O75197-1.2	R1146N	Pathogenic	0.984
LRP5	O75197-1.2	R1146P	Pathogenic	0.994
LRP5	O75197-1.2	R1146Q	Pathogenic	0.938
LRP5	O75197-1.2	R1146S	Pathogenic	0.991
LRP5	O75197-1.2	R1146T	Pathogenic	0.989
LRP5	O75197-1.2	R1146V	Pathogenic	0.997
LRP5	O75197-1.2	R1146W	Pathogenic	0.993
LRP5	O75197-1.2	R1146Y	Pathogenic	0.994
LRP5	O75197-1.2	L1147A	Neutral	0.016
LRP5	O75197-1.2	L1147C	Neutral	0.03
LRP5	O75197-1.2	L1147D	Neutral	0.153
LRP5	O75197-1.2	L1147E	Neutral	0.064
LRP5	O75197-1.2	L1147F	Neutral	0.018
LRP5	O75197-1.2	L1147G	Neutral	0.251
LRP5	O75197-1.2	L1147H	Neutral	0.122
LRP5	O75197-1.2	L1147I	Neutral	0.002
LRP5	O75197-1.2	L1147K	Neutral	0.016
LRP5	O75197-1.2	L1147M	Neutral	0.001
LRP5	O75197-1.2	L1147N	Neutral	0.065
LRP5	O75197-1.2	L1147P	Neutral	0.183
LRP5	O75197-1.2	L1147Q	Neutral	0.032
LRP5	O75197-1.2	L1147R	Neutral	0.016
LRP5	O75197-1.2	L1147S	Neutral	0.035
LRP5	O75197-1.2	L1147T	Neutral	0.016
LRP5	O75197-1.2	L1147V	Neutral	0.004
LRP5	O75197-1.2	L1147W	Neutral	0.097
LRP5	O75197-1.2	L1147Y	Neutral	0.03
LRP5	O75197-1.2	T1148A	Neutral	0.205
LRP5	O75197-1.2	T1148C	Neutral	0.307
LRP5	O75197-1.2	T1148D	Neutral	0.254
LRP5	O75197-1.2	T1148E	Neutral	0.273
LRP5	O75197-1.2	T1148F	Neutral	0.382
LRP5	O75197-1.2	T1148G	Pathogenic	0.658
LRP5	O75197-1.2	T1148H	Pathogenic	0.691
LRP5	O75197-1.2	T1148I	Neutral	0.17
LRP5	O75197-1.2	T1148K	Neutral	0.208
LRP5	O75197-1.2	T1148L	Neutral	0.183
LRP5	O75197-1.2	T1148M	Neutral	0.254
LRP5	O75197-1.2	T1148N	Neutral	0.115
LRP5	O75197-1.2	T1148P	Neutral	0.36
LRP5	O75197-1.2	T1148Q	Neutral	0.351
LRP5	O75197-1.2	T1148R	Neutral	0.202
LRP5	O75197-1.2	T1148S	Neutral	0.064
LRP5	O75197-1.2	T1148V	Neutral	0.105
LRP5	O75197-1.2	T1148W	Neutral	0.281
LRP5	O75197-1.2	T1148Y	Pathogenic	0.562
LRP5	O75197-1.2	L1149A	Pathogenic	0.925
LRP5	O75197-1.2	L1149C	Pathogenic	0.959
LRP5	O75197-1.2	L1149D	Pathogenic	0.993
LRP5	O75197-1.2	L1149E	Pathogenic	0.981
LRP5	O75197-1.2	L1149F	Pathogenic	0.934
LRP5	O75197-1.2	L1149G	Pathogenic	0.996
LRP5	O75197-1.2	L1149H	Pathogenic	0.991
LRP5	O75197-1.2	L1149I	Pathogenic	0.604
LRP5	O75197-1.2	L1149K	Pathogenic	0.927
LRP5	O75197-1.2	L1149M	Pathogenic	0.524
LRP5	O75197-1.2	L1149N	Pathogenic	0.982
LRP5	O75197-1.2	L1149P	Pathogenic	0.994
LRP5	O75197-1.2	L1149Q	Pathogenic	0.962
LRP5	O75197-1.2	L1149R	Pathogenic	0.925
LRP5	O75197-1.2	L1149S	Pathogenic	0.965
LRP5	O75197-1.2	L1149T	Pathogenic	0.925
LRP5	O75197-1.2	L1149V	Pathogenic	0.762
LRP5	O75197-1.2	L1149W	Pathogenic	0.988
LRP5	O75197-1.2	L1149Y	Pathogenic	0.959
LRP5	O75197-1.2	E1150A	Neutral	0.378
LRP5	O75197-1.2	E1150C	Pathogenic	0.906
LRP5	O75197-1.2	E1150D	Neutral	0.044
LRP5	O75197-1.2	E1150F	Pathogenic	0.605
LRP5	O75197-1.2	E1150G	Pathogenic	0.702
LRP5	O75197-1.2	E1150H	Neutral	0.198
LRP5	O75197-1.2	E1150I	Pathogenic	0.606
LRP5	O75197-1.2	E1150K	Neutral	0.103
LRP5	O75197-1.2	E1150L	Pathogenic	0.628
LRP5	O75197-1.2	E1150M	Neutral	0.458
LRP5	O75197-1.2	E1150N	Neutral	0.32
LRP5	O75197-1.2	E1150P	Neutral	0.304
LRP5	O75197-1.2	E1150Q	Neutral	0.035
LRP5	O75197-1.2	E1150R	Neutral	0.252
LRP5	O75197-1.2	E1150S	Neutral	0.215
LRP5	O75197-1.2	E1150T	Neutral	0.398
LRP5	O75197-1.2	E1150V	Neutral	0.465
LRP5	O75197-1.2	E1150W	Neutral	0.492
LRP5	O75197-1.2	E1150Y	Pathogenic	0.511
LRP5	O75197-1.2	D1151A	Pathogenic	0.94
LRP5	O75197-1.2	D1151C	Pathogenic	0.964
LRP5	O75197-1.2	D1151E	Neutral	0.3
LRP5	O75197-1.2	D1151F	Pathogenic	0.924
LRP5	O75197-1.2	D1151G	Pathogenic	0.868
LRP5	O75197-1.2	D1151H	Pathogenic	0.857
LRP5	O75197-1.2	D1151I	Pathogenic	0.925
LRP5	O75197-1.2	D1151K	Pathogenic	0.915
LRP5	O75197-1.2	D1151L	Pathogenic	0.976
LRP5	O75197-1.2	D1151M	Pathogenic	0.954
LRP5	O75197-1.2	D1151N	Pathogenic	0.563
LRP5	O75197-1.2	D1151P	Pathogenic	0.787
LRP5	O75197-1.2	D1151Q	Pathogenic	0.731
LRP5	O75197-1.2	D1151R	Pathogenic	0.969
LRP5	O75197-1.2	D1151S	Pathogenic	0.699
LRP5	O75197-1.2	D1151T	Pathogenic	0.848
LRP5	O75197-1.2	D1151V	Pathogenic	0.955
LRP5	O75197-1.2	D1151W	Pathogenic	0.959
LRP5	O75197-1.2	D1151Y	Pathogenic	0.962
LRP5	O75197-1.2	A1152C	Neutral	0.085
LRP5	O75197-1.2	A1152D	Neutral	0.373
LRP5	O75197-1.2	A1152E	Neutral	0.176
LRP5	O75197-1.2	A1152F	Neutral	0.279
LRP5	O75197-1.2	A1152G	Neutral	0.114
LRP5	O75197-1.2	A1152H	Pathogenic	0.561
LRP5	O75197-1.2	A1152I	Neutral	0.113
LRP5	O75197-1.2	A1152K	Neutral	0.13
LRP5	O75197-1.2	A1152L	Neutral	0.123
LRP5	O75197-1.2	A1152M	Neutral	0.176
LRP5	O75197-1.2	A1152N	Neutral	0.407
LRP5	O75197-1.2	A1152P	Neutral	0.262
LRP5	O75197-1.2	A1152Q	Neutral	0.236
LRP5	O75197-1.2	A1152R	Neutral	0.126
LRP5	O75197-1.2	A1152S	Neutral	0.04
LRP5	O75197-1.2	A1152T	Neutral	0.138
LRP5	O75197-1.2	A1152V	Neutral	0.068
LRP5	O75197-1.2	A1152W	Neutral	0.427
LRP5	O75197-1.2	A1152Y	Neutral	0.445
LRP5	O75197-1.2	N1153A	Pathogenic	0.923
LRP5	O75197-1.2	N1153C	Pathogenic	0.954
LRP5	O75197-1.2	N1153D	Neutral	0.461
LRP5	O75197-1.2	N1153E	Pathogenic	0.743
LRP5	O75197-1.2	N1153F	Pathogenic	0.905
LRP5	O75197-1.2	N1153G	Pathogenic	0.623
LRP5	O75197-1.2	N1153H	Neutral	0.335
LRP5	O75197-1.2	N1153I	Pathogenic	0.905
LRP5	O75197-1.2	N1153K	Pathogenic	0.669
LRP5	O75197-1.2	N1153L	Pathogenic	0.913
LRP5	O75197-1.2	N1153M	Pathogenic	0.84
LRP5	O75197-1.2	N1153P	Pathogenic	0.896
LRP5	O75197-1.2	N1153Q	Pathogenic	0.678
LRP5	O75197-1.2	N1153R	Pathogenic	0.662
LRP5	O75197-1.2	N1153S	Neutral	0.369
LRP5	O75197-1.2	N1153T	Pathogenic	0.585
LRP5	O75197-1.2	N1153V	Pathogenic	0.943
LRP5	O75197-1.2	N1153W	Pathogenic	0.948
LRP5	O75197-1.2	N1153Y	Pathogenic	0.867
LRP5	O75197-1.2	I1154A	Pathogenic	0.737
LRP5	O75197-1.2	I1154C	Pathogenic	0.841
LRP5	O75197-1.2	I1154D	Pathogenic	0.912
LRP5	O75197-1.2	I1154E	Pathogenic	0.923
LRP5	O75197-1.2	I1154F	Pathogenic	0.789
LRP5	O75197-1.2	I1154G	Pathogenic	0.983
LRP5	O75197-1.2	I1154H	Pathogenic	0.96
LRP5	O75197-1.2	I1154K	Pathogenic	0.898
LRP5	O75197-1.2	I1154L	Neutral	0.275
LRP5	O75197-1.2	I1154M	Neutral	0.432
LRP5	O75197-1.2	I1154N	Pathogenic	0.924
LRP5	O75197-1.2	I1154P	Pathogenic	0.975
LRP5	O75197-1.2	I1154Q	Pathogenic	0.946
LRP5	O75197-1.2	I1154R	Pathogenic	0.894
LRP5	O75197-1.2	I1154S	Pathogenic	0.864
LRP5	O75197-1.2	I1154T	Pathogenic	0.737
LRP5	O75197-1.2	I1154V	Neutral	0.073
LRP5	O75197-1.2	I1154W	Pathogenic	0.986
LRP5	O75197-1.2	I1154Y	Pathogenic	0.843
LRP5	O75197-1.2	V1155A	Neutral	0.027
LRP5	O75197-1.2	V1155C	Neutral	0.137
LRP5	O75197-1.2	V1155D	Neutral	0.236
LRP5	O75197-1.2	V1155E	Neutral	0.104
LRP5	O75197-1.2	V1155F	Neutral	0.103
LRP5	O75197-1.2	V1155G	Neutral	0.364
LRP5	O75197-1.2	V1155H	Neutral	0.409
LRP5	O75197-1.2	V1155I	Neutral	0.001
LRP5	O75197-1.2	V1155K	Neutral	0.075
LRP5	O75197-1.2	V1155L	Neutral	0.014
LRP5	O75197-1.2	V1155M	Neutral	0.02
LRP5	O75197-1.2	V1155N	Neutral	0.265
LRP5	O75197-1.2	V1155P	Neutral	0.277
LRP5	O75197-1.2	V1155Q	Neutral	0.143
LRP5	O75197-1.2	V1155R	Neutral	0.193
LRP5	O75197-1.2	V1155S	Neutral	0.159
LRP5	O75197-1.2	V1155T	Neutral	0.027
LRP5	O75197-1.2	V1155W	Neutral	0.402
LRP5	O75197-1.2	V1155Y	Neutral	0.131
LRP5	O75197-1.2	Q1156A	Pathogenic	0.982
LRP5	O75197-1.2	Q1156C	Pathogenic	0.997
LRP5	O75197-1.2	Q1156D	Pathogenic	0.949
LRP5	O75197-1.2	Q1156E	Pathogenic	0.701
LRP5	O75197-1.2	Q1156F	Pathogenic	0.993
LRP5	O75197-1.2	Q1156G	Pathogenic	0.995
LRP5	O75197-1.2	Q1156H	Pathogenic	0.958
LRP5	O75197-1.2	Q1156I	Pathogenic	0.993
LRP5	O75197-1.2	Q1156K	Pathogenic	0.835
LRP5	O75197-1.2	Q1156L	Pathogenic	0.981
LRP5	O75197-1.2	Q1156M	Pathogenic	0.895
LRP5	O75197-1.2	Q1156N	Pathogenic	0.956
LRP5	O75197-1.2	Q1156P	Pathogenic	0.976
LRP5	O75197-1.2	Q1156R	Pathogenic	0.831
LRP5	O75197-1.2	Q1156S	Pathogenic	0.962
LRP5	O75197-1.2	Q1156T	Pathogenic	0.984
LRP5	O75197-1.2	Q1156V	Pathogenic	0.988
LRP5	O75197-1.2	Q1156W	Pathogenic	0.968
LRP5	O75197-1.2	Q1156Y	Pathogenic	0.97
LRP5	O75197-1.2	P1157A	Pathogenic	0.968
LRP5	O75197-1.2	P1157C	Pathogenic	0.997
LRP5	O75197-1.2	P1157D	Pathogenic	0.923
LRP5	O75197-1.2	P1157E	Pathogenic	0.93
LRP5	O75197-1.2	P1157F	Pathogenic	0.998
LRP5	O75197-1.2	P1157G	Pathogenic	0.986
LRP5	O75197-1.2	P1157H	Pathogenic	0.987
LRP5	O75197-1.2	P1157I	Pathogenic	0.993
LRP5	O75197-1.2	P1157K	Pathogenic	0.902
LRP5	O75197-1.2	P1157L	Pathogenic	0.994
LRP5	O75197-1.2	P1157M	Pathogenic	0.988
LRP5	O75197-1.2	P1157N	Pathogenic	0.977
LRP5	O75197-1.2	P1157Q	Pathogenic	0.95
LRP5	O75197-1.2	P1157R	Pathogenic	0.964
LRP5	O75197-1.2	P1157S	Pathogenic	0.958
LRP5	O75197-1.2	P1157T	Pathogenic	0.968
LRP5	O75197-1.2	P1157V	Pathogenic	0.989
LRP5	O75197-1.2	P1157W	Pathogenic	0.997
LRP5	O75197-1.2	P1157Y	Pathogenic	0.997
LRP5	O75197-1.2	L1158A	Neutral	0.003
LRP5	O75197-1.2	L1158C	Neutral	0.006
LRP5	O75197-1.2	L1158D	Neutral	0.037
LRP5	O75197-1.2	L1158E	Neutral	0.014
LRP5	O75197-1.2	L1158F	Neutral	0.004
LRP5	O75197-1.2	L1158G	Neutral	0.067
LRP5	O75197-1.2	L1158H	Neutral	0.029
LRP5	O75197-1.2	L1158I	Neutral	0.0
LRP5	O75197-1.2	L1158K	Neutral	0.004
LRP5	O75197-1.2	L1158M	Neutral	0.0
LRP5	O75197-1.2	L1158N	Neutral	0.015
LRP5	O75197-1.2	L1158P	Neutral	0.046
LRP5	O75197-1.2	L1158Q	Neutral	0.007
LRP5	O75197-1.2	L1158R	Neutral	0.003
LRP5	O75197-1.2	L1158S	Neutral	0.008
LRP5	O75197-1.2	L1158T	Neutral	0.003
LRP5	O75197-1.2	L1158V	Neutral	0.001
LRP5	O75197-1.2	L1158W	Neutral	0.022
LRP5	O75197-1.2	L1158Y	Neutral	0.007
LRP5	O75197-1.2	G1159A	Pathogenic	0.84
LRP5	O75197-1.2	G1159C	Pathogenic	0.987
LRP5	O75197-1.2	G1159D	Pathogenic	0.91
LRP5	O75197-1.2	G1159E	Pathogenic	0.971
LRP5	O75197-1.2	G1159F	Pathogenic	0.972
LRP5	O75197-1.2	G1159H	Pathogenic	0.981
LRP5	O75197-1.2	G1159I	Pathogenic	0.991
LRP5	O75197-1.2	G1159K	Pathogenic	0.959
LRP5	O75197-1.2	G1159L	Pathogenic	0.992
LRP5	O75197-1.2	G1159M	Pathogenic	0.983
LRP5	O75197-1.2	G1159N	Pathogenic	0.794
LRP5	O75197-1.2	G1159P	Pathogenic	0.97
LRP5	O75197-1.2	G1159Q	Pathogenic	0.98
LRP5	O75197-1.2	G1159R	Pathogenic	0.958
LRP5	O75197-1.2	G1159S	Pathogenic	0.869
LRP5	O75197-1.2	G1159T	Pathogenic	0.98
LRP5	O75197-1.2	G1159V	Pathogenic	0.984
LRP5	O75197-1.2	G1159W	Pathogenic	0.88
LRP5	O75197-1.2	G1159Y	Pathogenic	0.987
LRP5	O75197-1.2	L1160A	Pathogenic	0.97
LRP5	O75197-1.2	L1160C	Pathogenic	0.984
LRP5	O75197-1.2	L1160D	Pathogenic	0.997
LRP5	O75197-1.2	L1160E	Pathogenic	0.993
LRP5	O75197-1.2	L1160F	Pathogenic	0.974
LRP5	O75197-1.2	L1160G	Pathogenic	0.999
LRP5	O75197-1.2	L1160H	Pathogenic	0.996
LRP5	O75197-1.2	L1160I	Pathogenic	0.801
LRP5	O75197-1.2	L1160K	Pathogenic	0.971
LRP5	O75197-1.2	L1160M	Pathogenic	0.744
LRP5	O75197-1.2	L1160N	Pathogenic	0.993
LRP5	O75197-1.2	L1160P	Pathogenic	0.998
LRP5	O75197-1.2	L1160Q	Pathogenic	0.985
LRP5	O75197-1.2	L1160R	Pathogenic	0.97
LRP5	O75197-1.2	L1160S	Pathogenic	0.987
LRP5	O75197-1.2	L1160T	Pathogenic	0.97
LRP5	O75197-1.2	L1160V	Pathogenic	0.894
LRP5	O75197-1.2	L1160W	Pathogenic	0.995
LRP5	O75197-1.2	L1160Y	Pathogenic	0.984
LRP5	O75197-1.2	T1161A	Pathogenic	0.904
LRP5	O75197-1.2	T1161C	Pathogenic	0.942
LRP5	O75197-1.2	T1161D	Pathogenic	0.926
LRP5	O75197-1.2	T1161E	Pathogenic	0.932
LRP5	O75197-1.2	T1161F	Pathogenic	0.958
LRP5	O75197-1.2	T1161G	Pathogenic	0.986
LRP5	O75197-1.2	T1161H	Pathogenic	0.988
LRP5	O75197-1.2	T1161I	Pathogenic	0.882
LRP5	O75197-1.2	T1161K	Pathogenic	0.906
LRP5	O75197-1.2	T1161L	Pathogenic	0.891
LRP5	O75197-1.2	T1161M	Pathogenic	0.926
LRP5	O75197-1.2	T1161N	Pathogenic	0.827
LRP5	O75197-1.2	T1161P	Pathogenic	0.954
LRP5	O75197-1.2	T1161Q	Pathogenic	0.952
LRP5	O75197-1.2	T1161R	Pathogenic	0.903
LRP5	O75197-1.2	T1161S	Pathogenic	0.717
LRP5	O75197-1.2	T1161V	Pathogenic	0.811
LRP5	O75197-1.2	T1161W	Pathogenic	0.935
LRP5	O75197-1.2	T1161Y	Pathogenic	0.979
LRP5	O75197-1.2	I1162A	Neutral	0.21
LRP5	O75197-1.2	I1162C	Neutral	0.334
LRP5	O75197-1.2	I1162D	Neutral	0.494
LRP5	O75197-1.2	I1162E	Pathogenic	0.53
LRP5	O75197-1.2	I1162F	Neutral	0.261
LRP5	O75197-1.2	I1162G	Pathogenic	0.846
LRP5	O75197-1.2	I1162H	Pathogenic	0.695
LRP5	O75197-1.2	I1162K	Neutral	0.454
LRP5	O75197-1.2	I1162L	Neutral	0.035
LRP5	O75197-1.2	I1162M	Neutral	0.067
LRP5	O75197-1.2	I1162N	Pathogenic	0.533
LRP5	O75197-1.2	I1162P	Pathogenic	0.787
LRP5	O75197-1.2	I1162Q	Pathogenic	0.623
LRP5	O75197-1.2	I1162R	Neutral	0.445
LRP5	O75197-1.2	I1162S	Neutral	0.375
LRP5	O75197-1.2	I1162T	Neutral	0.209
LRP5	O75197-1.2	I1162V	Neutral	0.007
LRP5	O75197-1.2	I1162W	Pathogenic	0.866
LRP5	O75197-1.2	I1162Y	Neutral	0.337
LRP5	O75197-1.2	L1163A	Neutral	0.22
LRP5	O75197-1.2	L1163C	Neutral	0.347
LRP5	O75197-1.2	L1163D	Pathogenic	0.759
LRP5	O75197-1.2	L1163E	Pathogenic	0.545
LRP5	O75197-1.2	L1163F	Neutral	0.243
LRP5	O75197-1.2	L1163G	Pathogenic	0.854
LRP5	O75197-1.2	L1163H	Pathogenic	0.708
LRP5	O75197-1.2	L1163I	Neutral	0.034
LRP5	O75197-1.2	L1163K	Neutral	0.225
LRP5	O75197-1.2	L1163M	Neutral	0.024
LRP5	O75197-1.2	L1163N	Pathogenic	0.548
LRP5	O75197-1.2	L1163P	Pathogenic	0.796
LRP5	O75197-1.2	L1163Q	Neutral	0.366
LRP5	O75197-1.2	L1163R	Neutral	0.219
LRP5	O75197-1.2	L1163S	Neutral	0.389
LRP5	O75197-1.2	L1163T	Neutral	0.219
LRP5	O75197-1.2	L1163V	Neutral	0.068
LRP5	O75197-1.2	L1163W	Pathogenic	0.652
LRP5	O75197-1.2	L1163Y	Neutral	0.35
LRP5	O75197-1.2	G1164A	Neutral	0.445
LRP5	O75197-1.2	G1164C	Pathogenic	0.923
LRP5	O75197-1.2	G1164D	Pathogenic	0.609
LRP5	O75197-1.2	G1164E	Pathogenic	0.838
LRP5	O75197-1.2	G1164F	Pathogenic	0.844
LRP5	O75197-1.2	G1164H	Pathogenic	0.889
LRP5	O75197-1.2	G1164I	Pathogenic	0.943
LRP5	O75197-1.2	G1164K	Pathogenic	0.784
LRP5	O75197-1.2	G1164L	Pathogenic	0.948
LRP5	O75197-1.2	G1164M	Pathogenic	0.9
LRP5	O75197-1.2	G1164N	Neutral	0.371
LRP5	O75197-1.2	G1164P	Pathogenic	0.832
LRP5	O75197-1.2	G1164Q	Pathogenic	0.882
LRP5	O75197-1.2	G1164R	Pathogenic	0.778
LRP5	O75197-1.2	G1164S	Pathogenic	0.503
LRP5	O75197-1.2	G1164T	Pathogenic	0.882
LRP5	O75197-1.2	G1164V	Pathogenic	0.904
LRP5	O75197-1.2	G1164W	Pathogenic	0.529
LRP5	O75197-1.2	G1164Y	Pathogenic	0.918
LRP5	O75197-1.2	K1165A	Neutral	0.01
LRP5	O75197-1.2	K1165C	Neutral	0.049
LRP5	O75197-1.2	K1165D	Neutral	0.026
LRP5	O75197-1.2	K1165E	Neutral	0.003
LRP5	O75197-1.2	K1165F	Neutral	0.026
LRP5	O75197-1.2	K1165G	Neutral	0.037
LRP5	O75197-1.2	K1165H	Neutral	0.012
LRP5	O75197-1.2	K1165I	Neutral	0.025
LRP5	O75197-1.2	K1165L	Neutral	0.009
LRP5	O75197-1.2	K1165M	Neutral	0.005
LRP5	O75197-1.2	K1165N	Neutral	0.008
LRP5	O75197-1.2	K1165P	Neutral	0.007
LRP5	O75197-1.2	K1165Q	Neutral	0.002
LRP5	O75197-1.2	K1165R	Neutral	0.001
LRP5	O75197-1.2	K1165S	Neutral	0.004
LRP5	O75197-1.2	K1165T	Neutral	0.011
LRP5	O75197-1.2	K1165V	Neutral	0.014
LRP5	O75197-1.2	K1165W	Neutral	0.017
LRP5	O75197-1.2	K1165Y	Neutral	0.018
LRP5	O75197-1.2	H1166A	Pathogenic	0.944
LRP5	O75197-1.2	H1166C	Pathogenic	0.966
LRP5	O75197-1.2	H1166D	Pathogenic	0.749
LRP5	O75197-1.2	H1166E	Pathogenic	0.532
LRP5	O75197-1.2	H1166F	Pathogenic	0.607
LRP5	O75197-1.2	H1166G	Pathogenic	0.944
LRP5	O75197-1.2	H1166I	Pathogenic	0.935
LRP5	O75197-1.2	H1166K	Pathogenic	0.714
LRP5	O75197-1.2	H1166L	Pathogenic	0.94
LRP5	O75197-1.2	H1166M	Pathogenic	0.887
LRP5	O75197-1.2	H1166N	Neutral	0.274
LRP5	O75197-1.2	H1166P	Pathogenic	0.923
LRP5	O75197-1.2	H1166Q	Pathogenic	0.625
LRP5	O75197-1.2	H1166R	Neutral	0.442
LRP5	O75197-1.2	H1166S	Pathogenic	0.848
LRP5	O75197-1.2	H1166T	Pathogenic	0.948
LRP5	O75197-1.2	H1166V	Pathogenic	0.96
LRP5	O75197-1.2	H1166W	Pathogenic	0.748
LRP5	O75197-1.2	H1166Y	Neutral	0.102
LRP5	O75197-1.2	L1167A	Pathogenic	0.943
LRP5	O75197-1.2	L1167C	Pathogenic	0.969
LRP5	O75197-1.2	L1167D	Pathogenic	0.995
LRP5	O75197-1.2	L1167E	Pathogenic	0.986
LRP5	O75197-1.2	L1167F	Pathogenic	0.949
LRP5	O75197-1.2	L1167G	Pathogenic	0.997
LRP5	O75197-1.2	L1167H	Pathogenic	0.993
LRP5	O75197-1.2	L1167I	Pathogenic	0.67
LRP5	O75197-1.2	L1167K	Pathogenic	0.944
LRP5	O75197-1.2	L1167M	Pathogenic	0.594
LRP5	O75197-1.2	L1167N	Pathogenic	0.986
LRP5	O75197-1.2	L1167P	Pathogenic	0.996
LRP5	O75197-1.2	L1167Q	Pathogenic	0.971
LRP5	O75197-1.2	L1167R	Pathogenic	0.942
LRP5	O75197-1.2	L1167S	Pathogenic	0.974
LRP5	O75197-1.2	L1167T	Pathogenic	0.943
LRP5	O75197-1.2	L1167V	Pathogenic	0.81
LRP5	O75197-1.2	L1167W	Pathogenic	0.991
LRP5	O75197-1.2	L1167Y	Pathogenic	0.969
LRP5	O75197-1.2	Y1168A	Pathogenic	0.999
LRP5	O75197-1.2	Y1168C	Pathogenic	0.999
LRP5	O75197-1.2	Y1168D	Pathogenic	0.999
LRP5	O75197-1.2	Y1168E	Pathogenic	0.997
LRP5	O75197-1.2	Y1168F	Pathogenic	0.728
LRP5	O75197-1.2	Y1168G	Pathogenic	0.999
LRP5	O75197-1.2	Y1168H	Pathogenic	0.888
LRP5	O75197-1.2	Y1168I	Pathogenic	0.996
LRP5	O75197-1.2	Y1168K	Pathogenic	0.996
LRP5	O75197-1.2	Y1168L	Pathogenic	0.996
LRP5	O75197-1.2	Y1168M	Pathogenic	0.997
LRP5	O75197-1.2	Y1168N	Pathogenic	0.997
LRP5	O75197-1.2	Y1168P	Pathogenic	1.0
LRP5	O75197-1.2	Y1168Q	Pathogenic	0.994
LRP5	O75197-1.2	Y1168R	Pathogenic	0.996
LRP5	O75197-1.2	Y1168S	Pathogenic	0.998
LRP5	O75197-1.2	Y1168T	Pathogenic	0.999
LRP5	O75197-1.2	Y1168V	Pathogenic	0.997
LRP5	O75197-1.2	Y1168W	Pathogenic	0.84
LRP5	O75197-1.2	W1169A	Pathogenic	1.0
LRP5	O75197-1.2	W1169C	Pathogenic	0.999
LRP5	O75197-1.2	W1169D	Pathogenic	1.0
LRP5	O75197-1.2	W1169E	Pathogenic	0.999
LRP5	O75197-1.2	W1169F	Pathogenic	0.99
LRP5	O75197-1.2	W1169G	Pathogenic	0.998
LRP5	O75197-1.2	W1169H	Pathogenic	0.998
LRP5	O75197-1.2	W1169I	Pathogenic	1.0
LRP5	O75197-1.2	W1169K	Pathogenic	0.999
LRP5	O75197-1.2	W1169L	Pathogenic	1.0
LRP5	O75197-1.2	W1169M	Pathogenic	0.998
LRP5	O75197-1.2	W1169N	Pathogenic	1.0
LRP5	O75197-1.2	W1169P	Pathogenic	1.0
LRP5	O75197-1.2	W1169Q	Pathogenic	0.998
LRP5	O75197-1.2	W1169R	Pathogenic	0.999
LRP5	O75197-1.2	W1169S	Pathogenic	0.999
LRP5	O75197-1.2	W1169T	Pathogenic	0.999
LRP5	O75197-1.2	W1169V	Pathogenic	1.0
LRP5	O75197-1.2	W1169Y	Pathogenic	0.942
LRP5	O75197-1.2	I1170A	Pathogenic	0.588
LRP5	O75197-1.2	I1170C	Pathogenic	0.729
LRP5	O75197-1.2	I1170D	Pathogenic	0.84
LRP5	O75197-1.2	I1170E	Pathogenic	0.859
LRP5	O75197-1.2	I1170F	Pathogenic	0.655
LRP5	O75197-1.2	I1170G	Pathogenic	0.967
LRP5	O75197-1.2	I1170H	Pathogenic	0.925
LRP5	O75197-1.2	I1170K	Pathogenic	0.817
LRP5	O75197-1.2	I1170L	Neutral	0.162
LRP5	O75197-1.2	I1170M	Neutral	0.279
LRP5	O75197-1.2	I1170N	Pathogenic	0.86
LRP5	O75197-1.2	I1170P	Pathogenic	0.952
LRP5	O75197-1.2	I1170Q	Pathogenic	0.899
LRP5	O75197-1.2	I1170R	Pathogenic	0.812
LRP5	O75197-1.2	I1170S	Pathogenic	0.763
LRP5	O75197-1.2	I1170T	Pathogenic	0.587
LRP5	O75197-1.2	I1170V	Neutral	0.038
LRP5	O75197-1.2	I1170W	Pathogenic	0.972
LRP5	O75197-1.2	I1170Y	Pathogenic	0.732
LRP5	O75197-1.2	D1171A	Pathogenic	0.992
LRP5	O75197-1.2	D1171C	Pathogenic	0.996
LRP5	O75197-1.2	D1171E	Pathogenic	0.782
LRP5	O75197-1.2	D1171F	Pathogenic	0.99
LRP5	O75197-1.2	D1171G	Pathogenic	0.982
LRP5	O75197-1.2	D1171H	Pathogenic	0.98
LRP5	O75197-1.2	D1171I	Pathogenic	0.99
LRP5	O75197-1.2	D1171K	Pathogenic	0.989
LRP5	O75197-1.2	D1171L	Pathogenic	0.997
LRP5	O75197-1.2	D1171M	Pathogenic	0.994
LRP5	O75197-1.2	D1171N	Pathogenic	0.915
LRP5	O75197-1.2	D1171P	Pathogenic	0.969
LRP5	O75197-1.2	D1171Q	Pathogenic	0.958
LRP5	O75197-1.2	D1171R	Pathogenic	0.996
LRP5	O75197-1.2	D1171S	Pathogenic	0.951
LRP5	O75197-1.2	D1171T	Pathogenic	0.979
LRP5	O75197-1.2	D1171V	Pathogenic	0.994
LRP5	O75197-1.2	D1171W	Pathogenic	0.995
LRP5	O75197-1.2	D1171Y	Pathogenic	0.995
LRP5	O75197-1.2	R1172A	Pathogenic	0.731
LRP5	O75197-1.2	R1172C	Pathogenic	0.934
LRP5	O75197-1.2	R1172D	Pathogenic	0.958
LRP5	O75197-1.2	R1172E	Pathogenic	0.69
LRP5	O75197-1.2	R1172F	Pathogenic	0.882
LRP5	O75197-1.2	R1172G	Pathogenic	0.914
LRP5	O75197-1.2	R1172H	Pathogenic	0.532
LRP5	O75197-1.2	R1172I	Pathogenic	0.879
LRP5	O75197-1.2	R1172K	Neutral	0.256
LRP5	O75197-1.2	R1172L	Pathogenic	0.723
LRP5	O75197-1.2	R1172M	Pathogenic	0.566
LRP5	O75197-1.2	R1172N	Pathogenic	0.679
LRP5	O75197-1.2	R1172P	Pathogenic	0.856
LRP5	O75197-1.2	R1172Q	Neutral	0.337
LRP5	O75197-1.2	R1172S	Pathogenic	0.789
LRP5	O75197-1.2	R1172T	Pathogenic	0.748
LRP5	O75197-1.2	R1172V	Pathogenic	0.922
LRP5	O75197-1.2	R1172W	Pathogenic	0.831
LRP5	O75197-1.2	R1172Y	Pathogenic	0.839
LRP5	O75197-1.2	Q1173A	Pathogenic	0.953
LRP5	O75197-1.2	Q1173C	Pathogenic	0.991
LRP5	O75197-1.2	Q1173D	Pathogenic	0.873
LRP5	O75197-1.2	Q1173E	Neutral	0.462
LRP5	O75197-1.2	Q1173F	Pathogenic	0.981
LRP5	O75197-1.2	Q1173G	Pathogenic	0.988
LRP5	O75197-1.2	Q1173H	Pathogenic	0.894
LRP5	O75197-1.2	Q1173I	Pathogenic	0.981
LRP5	O75197-1.2	Q1173K	Pathogenic	0.65
LRP5	O75197-1.2	Q1173L	Pathogenic	0.95
LRP5	O75197-1.2	Q1173M	Pathogenic	0.758
LRP5	O75197-1.2	Q1173N	Pathogenic	0.89
LRP5	O75197-1.2	Q1173P	Pathogenic	0.936
LRP5	O75197-1.2	Q1173R	Pathogenic	0.643
LRP5	O75197-1.2	Q1173S	Pathogenic	0.903
LRP5	O75197-1.2	Q1173T	Pathogenic	0.957
LRP5	O75197-1.2	Q1173V	Pathogenic	0.967
LRP5	O75197-1.2	Q1173W	Pathogenic	0.916
LRP5	O75197-1.2	Q1173Y	Pathogenic	0.922
LRP5	O75197-1.2	Q1174A	Pathogenic	0.941
LRP5	O75197-1.2	Q1174C	Pathogenic	0.988
LRP5	O75197-1.2	Q1174D	Pathogenic	0.843
LRP5	O75197-1.2	Q1174E	Neutral	0.402
LRP5	O75197-1.2	Q1174F	Pathogenic	0.976
LRP5	O75197-1.2	Q1174G	Pathogenic	0.984
LRP5	O75197-1.2	Q1174H	Pathogenic	0.869
LRP5	O75197-1.2	Q1174I	Pathogenic	0.976
LRP5	O75197-1.2	Q1174K	Pathogenic	0.593
LRP5	O75197-1.2	Q1174L	Pathogenic	0.937
LRP5	O75197-1.2	Q1174M	Pathogenic	0.71
LRP5	O75197-1.2	Q1174N	Pathogenic	0.863
LRP5	O75197-1.2	Q1174P	Pathogenic	0.92
LRP5	O75197-1.2	Q1174R	Pathogenic	0.585
LRP5	O75197-1.2	Q1174S	Pathogenic	0.879
LRP5	O75197-1.2	Q1174T	Pathogenic	0.946
LRP5	O75197-1.2	Q1174V	Pathogenic	0.958
LRP5	O75197-1.2	Q1174W	Pathogenic	0.896
LRP5	O75197-1.2	Q1174Y	Pathogenic	0.902
LRP5	O75197-1.2	Q1175A	Pathogenic	0.984
LRP5	O75197-1.2	Q1175C	Pathogenic	0.997
LRP5	O75197-1.2	Q1175D	Pathogenic	0.955
LRP5	O75197-1.2	Q1175E	Pathogenic	0.726
LRP5	O75197-1.2	Q1175F	Pathogenic	0.994
LRP5	O75197-1.2	Q1175G	Pathogenic	0.996
LRP5	O75197-1.2	Q1175H	Pathogenic	0.963
LRP5	O75197-1.2	Q1175I	Pathogenic	0.994
LRP5	O75197-1.2	Q1175K	Pathogenic	0.852
LRP5	O75197-1.2	Q1175L	Pathogenic	0.983
LRP5	O75197-1.2	Q1175M	Pathogenic	0.906
LRP5	O75197-1.2	Q1175N	Pathogenic	0.961
LRP5	O75197-1.2	Q1175P	Pathogenic	0.979
LRP5	O75197-1.2	Q1175R	Pathogenic	0.847
LRP5	O75197-1.2	Q1175S	Pathogenic	0.966
LRP5	O75197-1.2	Q1175T	Pathogenic	0.986
LRP5	O75197-1.2	Q1175V	Pathogenic	0.989
LRP5	O75197-1.2	Q1175W	Pathogenic	0.971
LRP5	O75197-1.2	Q1175Y	Pathogenic	0.973
LRP5	O75197-1.2	M1176A	Pathogenic	0.93
LRP5	O75197-1.2	M1176C	Pathogenic	0.962
LRP5	O75197-1.2	M1176D	Pathogenic	0.98
LRP5	O75197-1.2	M1176E	Pathogenic	0.949
LRP5	O75197-1.2	M1176F	Pathogenic	0.867
LRP5	O75197-1.2	M1176G	Pathogenic	0.989
LRP5	O75197-1.2	M1176H	Pathogenic	0.974
LRP5	O75197-1.2	M1176I	Pathogenic	0.683
LRP5	O75197-1.2	M1176K	Pathogenic	0.818
LRP5	O75197-1.2	M1176L	Neutral	0.437
LRP5	O75197-1.2	M1176N	Pathogenic	0.949
LRP5	O75197-1.2	M1176P	Pathogenic	0.984
LRP5	O75197-1.2	M1176Q	Pathogenic	0.746
LRP5	O75197-1.2	M1176R	Pathogenic	0.813
LRP5	O75197-1.2	M1176S	Pathogenic	0.908
LRP5	O75197-1.2	M1176T	Pathogenic	0.93
LRP5	O75197-1.2	M1176V	Pathogenic	0.775
LRP5	O75197-1.2	M1176W	Pathogenic	0.926
LRP5	O75197-1.2	M1176Y	Pathogenic	0.962
LRP5	O75197-1.2	I1177A	Pathogenic	0.95
LRP5	O75197-1.2	I1177C	Pathogenic	0.973
LRP5	O75197-1.2	I1177D	Pathogenic	0.986
LRP5	O75197-1.2	I1177E	Pathogenic	0.988
LRP5	O75197-1.2	I1177F	Pathogenic	0.962
LRP5	O75197-1.2	I1177G	Pathogenic	0.997
LRP5	O75197-1.2	I1177H	Pathogenic	0.994
LRP5	O75197-1.2	I1177K	Pathogenic	0.983
LRP5	O75197-1.2	I1177L	Pathogenic	0.72
LRP5	O75197-1.2	I1177M	Pathogenic	0.837
LRP5	O75197-1.2	I1177N	Pathogenic	0.988
LRP5	O75197-1.2	I1177P	Pathogenic	0.996
LRP5	O75197-1.2	I1177Q	Pathogenic	0.992
LRP5	O75197-1.2	I1177R	Pathogenic	0.983
LRP5	O75197-1.2	I1177S	Pathogenic	0.977
LRP5	O75197-1.2	I1177T	Pathogenic	0.95
LRP5	O75197-1.2	I1177V	Neutral	0.347
LRP5	O75197-1.2	I1177W	Pathogenic	0.998
LRP5	O75197-1.2	I1177Y	Pathogenic	0.973
LRP5	O75197-1.2	E1178A	Pathogenic	0.99
LRP5	O75197-1.2	E1178C	Pathogenic	0.999
LRP5	O75197-1.2	E1178D	Pathogenic	0.879
LRP5	O75197-1.2	E1178F	Pathogenic	0.996
LRP5	O75197-1.2	E1178G	Pathogenic	0.997
LRP5	O75197-1.2	E1178H	Pathogenic	0.975
LRP5	O75197-1.2	E1178I	Pathogenic	0.996
LRP5	O75197-1.2	E1178K	Pathogenic	0.947
LRP5	O75197-1.2	E1178L	Pathogenic	0.996
LRP5	O75197-1.2	E1178M	Pathogenic	0.992
LRP5	O75197-1.2	E1178N	Pathogenic	0.987
LRP5	O75197-1.2	E1178P	Pathogenic	0.986
LRP5	O75197-1.2	E1178Q	Pathogenic	0.851
LRP5	O75197-1.2	E1178R	Pathogenic	0.981
LRP5	O75197-1.2	E1178S	Pathogenic	0.977
LRP5	O75197-1.2	E1178T	Pathogenic	0.99
LRP5	O75197-1.2	E1178V	Pathogenic	0.993
LRP5	O75197-1.2	E1178W	Pathogenic	0.993
LRP5	O75197-1.2	E1178Y	Pathogenic	0.994
LRP5	O75197-1.2	R1179A	Pathogenic	0.785
LRP5	O75197-1.2	R1179C	Pathogenic	0.95
LRP5	O75197-1.2	R1179D	Pathogenic	0.968
LRP5	O75197-1.2	R1179E	Pathogenic	0.75
LRP5	O75197-1.2	R1179F	Pathogenic	0.909
LRP5	O75197-1.2	R1179G	Pathogenic	0.934
LRP5	O75197-1.2	R1179H	Pathogenic	0.604
LRP5	O75197-1.2	R1179I	Pathogenic	0.907
LRP5	O75197-1.2	R1179K	Neutral	0.316
LRP5	O75197-1.2	R1179L	Pathogenic	0.778
LRP5	O75197-1.2	R1179M	Pathogenic	0.637
LRP5	O75197-1.2	R1179N	Pathogenic	0.74
LRP5	O75197-1.2	R1179P	Pathogenic	0.889
LRP5	O75197-1.2	R1179Q	Neutral	0.406
LRP5	O75197-1.2	R1179S	Pathogenic	0.834
LRP5	O75197-1.2	R1179T	Pathogenic	0.8
LRP5	O75197-1.2	R1179V	Pathogenic	0.941
LRP5	O75197-1.2	R1179W	Pathogenic	0.869
LRP5	O75197-1.2	R1179Y	Pathogenic	0.875
LRP5	O75197-1.2	V1180A	Neutral	0.351
LRP5	O75197-1.2	V1180C	Pathogenic	0.756
LRP5	O75197-1.2	V1180D	Pathogenic	0.858
LRP5	O75197-1.2	V1180E	Pathogenic	0.694
LRP5	O75197-1.2	V1180F	Pathogenic	0.693
LRP5	O75197-1.2	V1180G	Pathogenic	0.918
LRP5	O75197-1.2	V1180H	Pathogenic	0.931
LRP5	O75197-1.2	V1180I	Neutral	0.026
LRP5	O75197-1.2	V1180K	Pathogenic	0.614
LRP5	O75197-1.2	V1180L	Neutral	0.212
LRP5	O75197-1.2	V1180M	Neutral	0.29
LRP5	O75197-1.2	V1180N	Pathogenic	0.876
LRP5	O75197-1.2	V1180P	Pathogenic	0.882
LRP5	O75197-1.2	V1180Q	Pathogenic	0.766
LRP5	O75197-1.2	V1180R	Pathogenic	0.824
LRP5	O75197-1.2	V1180S	Pathogenic	0.788
LRP5	O75197-1.2	V1180T	Neutral	0.35
LRP5	O75197-1.2	V1180W	Pathogenic	0.93
LRP5	O75197-1.2	V1180Y	Pathogenic	0.748
LRP5	O75197-1.2	E1181A	Neutral	0.223
LRP5	O75197-1.2	E1181C	Pathogenic	0.82
LRP5	O75197-1.2	E1181D	Neutral	0.021
LRP5	O75197-1.2	E1181F	Neutral	0.42
LRP5	O75197-1.2	E1181G	Pathogenic	0.527
LRP5	O75197-1.2	E1181H	Neutral	0.104
LRP5	O75197-1.2	E1181I	Neutral	0.421
LRP5	O75197-1.2	E1181K	Neutral	0.051
LRP5	O75197-1.2	E1181L	Neutral	0.444
LRP5	O75197-1.2	E1181M	Neutral	0.285
LRP5	O75197-1.2	E1181N	Neutral	0.182
LRP5	O75197-1.2	E1181P	Neutral	0.171
LRP5	O75197-1.2	E1181Q	Neutral	0.017
LRP5	O75197-1.2	E1181R	Neutral	0.137
LRP5	O75197-1.2	E1181S	Neutral	0.115
LRP5	O75197-1.2	E1181T	Neutral	0.239
LRP5	O75197-1.2	E1181V	Neutral	0.292
LRP5	O75197-1.2	E1181W	Neutral	0.314
LRP5	O75197-1.2	E1181Y	Neutral	0.331
LRP5	O75197-1.2	K1182A	Pathogenic	0.898
LRP5	O75197-1.2	K1182C	Pathogenic	0.979
LRP5	O75197-1.2	K1182D	Pathogenic	0.96
LRP5	O75197-1.2	K1182E	Pathogenic	0.702
LRP5	O75197-1.2	K1182F	Pathogenic	0.96
LRP5	O75197-1.2	K1182G	Pathogenic	0.971
LRP5	O75197-1.2	K1182H	Pathogenic	0.918
LRP5	O75197-1.2	K1182I	Pathogenic	0.959
LRP5	O75197-1.2	K1182L	Pathogenic	0.894
LRP5	O75197-1.2	K1182M	Pathogenic	0.808
LRP5	O75197-1.2	K1182N	Pathogenic	0.872
LRP5	O75197-1.2	K1182P	Pathogenic	0.863
LRP5	O75197-1.2	K1182Q	Pathogenic	0.621
LRP5	O75197-1.2	K1182R	Pathogenic	0.517
LRP5	O75197-1.2	K1182S	Pathogenic	0.798
LRP5	O75197-1.2	K1182T	Pathogenic	0.905
LRP5	O75197-1.2	K1182V	Pathogenic	0.926
LRP5	O75197-1.2	K1182W	Pathogenic	0.938
LRP5	O75197-1.2	K1182Y	Pathogenic	0.943
LRP5	O75197-1.2	T1183A	Neutral	0.156
LRP5	O75197-1.2	T1183C	Neutral	0.241
LRP5	O75197-1.2	T1183D	Neutral	0.197
LRP5	O75197-1.2	T1183E	Neutral	0.212
LRP5	O75197-1.2	T1183F	Neutral	0.308
LRP5	O75197-1.2	T1183G	Pathogenic	0.581
LRP5	O75197-1.2	T1183H	Pathogenic	0.617
LRP5	O75197-1.2	T1183I	Neutral	0.128
LRP5	O75197-1.2	T1183K	Neutral	0.159
LRP5	O75197-1.2	T1183L	Neutral	0.139
LRP5	O75197-1.2	T1183M	Neutral	0.197
LRP5	O75197-1.2	T1183N	Neutral	0.086
LRP5	O75197-1.2	T1183P	Neutral	0.289
LRP5	O75197-1.2	T1183Q	Neutral	0.28
LRP5	O75197-1.2	T1183R	Neutral	0.154
LRP5	O75197-1.2	T1183S	Neutral	0.047
LRP5	O75197-1.2	T1183V	Neutral	0.078
LRP5	O75197-1.2	T1183W	Neutral	0.22
LRP5	O75197-1.2	T1183Y	Neutral	0.48
LRP5	O75197-1.2	T1184A	Neutral	0.027
LRP5	O75197-1.2	T1184C	Neutral	0.046
LRP5	O75197-1.2	T1184D	Neutral	0.036
LRP5	O75197-1.2	T1184E	Neutral	0.039
LRP5	O75197-1.2	T1184F	Neutral	0.063
LRP5	O75197-1.2	T1184G	Neutral	0.174
LRP5	O75197-1.2	T1184H	Neutral	0.196
LRP5	O75197-1.2	T1184I	Neutral	0.022
LRP5	O75197-1.2	T1184K	Neutral	0.028
LRP5	O75197-1.2	T1184L	Neutral	0.024
LRP5	O75197-1.2	T1184M	Neutral	0.036
LRP5	O75197-1.2	T1184N	Neutral	0.014
LRP5	O75197-1.2	T1184P	Neutral	0.058
LRP5	O75197-1.2	T1184Q	Neutral	0.056
LRP5	O75197-1.2	T1184R	Neutral	0.027
LRP5	O75197-1.2	T1184S	Neutral	0.007
LRP5	O75197-1.2	T1184V	Neutral	0.013
LRP5	O75197-1.2	T1184W	Neutral	0.041
LRP5	O75197-1.2	T1184Y	Neutral	0.123
LRP5	O75197-1.2	G1185A	Pathogenic	0.699
LRP5	O75197-1.2	G1185C	Pathogenic	0.972
LRP5	O75197-1.2	G1185D	Pathogenic	0.818
LRP5	O75197-1.2	G1185E	Pathogenic	0.937
LRP5	O75197-1.2	G1185F	Pathogenic	0.94
LRP5	O75197-1.2	G1185H	Pathogenic	0.959
LRP5	O75197-1.2	G1185I	Pathogenic	0.979
LRP5	O75197-1.2	G1185K	Pathogenic	0.913
LRP5	O75197-1.2	G1185L	Pathogenic	0.981
LRP5	O75197-1.2	G1185M	Pathogenic	0.963
LRP5	O75197-1.2	G1185N	Pathogenic	0.63
LRP5	O75197-1.2	G1185P	Pathogenic	0.935
LRP5	O75197-1.2	G1185Q	Pathogenic	0.956
LRP5	O75197-1.2	G1185R	Pathogenic	0.91
LRP5	O75197-1.2	G1185S	Pathogenic	0.745
LRP5	O75197-1.2	G1185T	Pathogenic	0.956
LRP5	O75197-1.2	G1185V	Pathogenic	0.965
LRP5	O75197-1.2	G1185W	Pathogenic	0.764
LRP5	O75197-1.2	G1185Y	Pathogenic	0.97
LRP5	O75197-1.2	D1186A	Neutral	0.06
LRP5	O75197-1.2	D1186C	Neutral	0.098
LRP5	O75197-1.2	D1186E	Neutral	0.002
LRP5	O75197-1.2	D1186F	Neutral	0.047
LRP5	O75197-1.2	D1186G	Neutral	0.026
LRP5	O75197-1.2	D1186H	Neutral	0.024
LRP5	O75197-1.2	D1186I	Neutral	0.048
LRP5	O75197-1.2	D1186K	Neutral	0.042
LRP5	O75197-1.2	D1186L	Neutral	0.143
LRP5	O75197-1.2	D1186M	Neutral	0.077
LRP5	O75197-1.2	D1186N	Neutral	0.005
LRP5	O75197-1.2	D1186P	Neutral	0.015
LRP5	O75197-1.2	D1186Q	Neutral	0.011
LRP5	O75197-1.2	D1186R	Neutral	0.113
LRP5	O75197-1.2	D1186S	Neutral	0.009
LRP5	O75197-1.2	D1186T	Neutral	0.022
LRP5	O75197-1.2	D1186V	Neutral	0.08
LRP5	O75197-1.2	D1186W	Neutral	0.087
LRP5	O75197-1.2	D1186Y	Neutral	0.094
LRP5	O75197-1.2	K1187A	Neutral	0.051
LRP5	O75197-1.2	K1187C	Neutral	0.22
LRP5	O75197-1.2	K1187D	Neutral	0.129
LRP5	O75197-1.2	K1187E	Neutral	0.014
LRP5	O75197-1.2	K1187F	Neutral	0.129
LRP5	O75197-1.2	K1187G	Neutral	0.174
LRP5	O75197-1.2	K1187H	Neutral	0.064
LRP5	O75197-1.2	K1187I	Neutral	0.126
LRP5	O75197-1.2	K1187L	Neutral	0.049
LRP5	O75197-1.2	K1187M	Neutral	0.025
LRP5	O75197-1.2	K1187N	Neutral	0.04
LRP5	O75197-1.2	K1187P	Neutral	0.037
LRP5	O75197-1.2	K1187Q	Neutral	0.01
LRP5	O75197-1.2	K1187R	Neutral	0.007
LRP5	O75197-1.2	K1187S	Neutral	0.024
LRP5	O75197-1.2	K1187T	Neutral	0.056
LRP5	O75197-1.2	K1187V	Neutral	0.072
LRP5	O75197-1.2	K1187W	Neutral	0.086
LRP5	O75197-1.2	K1187Y	Neutral	0.092
LRP5	O75197-1.2	R1188A	Pathogenic	0.964
LRP5	O75197-1.2	R1188C	Pathogenic	0.993
LRP5	O75197-1.2	R1188D	Pathogenic	0.996
LRP5	O75197-1.2	R1188E	Pathogenic	0.956
LRP5	O75197-1.2	R1188F	Pathogenic	0.987
LRP5	O75197-1.2	R1188G	Pathogenic	0.99
LRP5	O75197-1.2	R1188H	Pathogenic	0.918
LRP5	O75197-1.2	R1188I	Pathogenic	0.986
LRP5	O75197-1.2	R1188K	Pathogenic	0.772
LRP5	O75197-1.2	R1188L	Pathogenic	0.963
LRP5	O75197-1.2	R1188M	Pathogenic	0.928
LRP5	O75197-1.2	R1188N	Pathogenic	0.954
LRP5	O75197-1.2	R1188P	Pathogenic	0.983
LRP5	O75197-1.2	R1188Q	Pathogenic	0.834
LRP5	O75197-1.2	R1188S	Pathogenic	0.974
LRP5	O75197-1.2	R1188T	Pathogenic	0.967
LRP5	O75197-1.2	R1188V	Pathogenic	0.992
LRP5	O75197-1.2	R1188W	Pathogenic	0.98
LRP5	O75197-1.2	R1188Y	Pathogenic	0.981
LRP5	O75197-1.2	T1189A	Pathogenic	0.683
LRP5	O75197-1.2	T1189C	Pathogenic	0.787
LRP5	O75197-1.2	T1189D	Pathogenic	0.74
LRP5	O75197-1.2	T1189E	Pathogenic	0.758
LRP5	O75197-1.2	T1189F	Pathogenic	0.838
LRP5	O75197-1.2	T1189G	Pathogenic	0.942
LRP5	O75197-1.2	T1189H	Pathogenic	0.949
LRP5	O75197-1.2	T1189I	Pathogenic	0.631
LRP5	O75197-1.2	T1189K	Pathogenic	0.687
LRP5	O75197-1.2	T1189L	Pathogenic	0.652
LRP5	O75197-1.2	T1189M	Pathogenic	0.74
LRP5	O75197-1.2	T1189N	Pathogenic	0.521
LRP5	O75197-1.2	T1189P	Pathogenic	0.825
LRP5	O75197-1.2	T1189Q	Pathogenic	0.819
LRP5	O75197-1.2	T1189R	Pathogenic	0.68
LRP5	O75197-1.2	T1189S	Neutral	0.366
LRP5	O75197-1.2	T1189V	Neutral	0.495
LRP5	O75197-1.2	T1189W	Pathogenic	0.766
LRP5	O75197-1.2	T1189Y	Pathogenic	0.915
LRP5	O75197-1.2	R1190A	Neutral	0.135
LRP5	O75197-1.2	R1190C	Neutral	0.449
LRP5	O75197-1.2	R1190D	Pathogenic	0.564
LRP5	O75197-1.2	R1190E	Neutral	0.114
LRP5	O75197-1.2	R1190F	Neutral	0.3
LRP5	O75197-1.2	R1190G	Neutral	0.378
LRP5	O75197-1.2	R1190H	Neutral	0.061
LRP5	O75197-1.2	R1190I	Neutral	0.294
LRP5	O75197-1.2	R1190K	Neutral	0.019
LRP5	O75197-1.2	R1190L	Neutral	0.13
LRP5	O75197-1.2	R1190M	Neutral	0.07
LRP5	O75197-1.2	R1190N	Neutral	0.108
LRP5	O75197-1.2	R1190P	Neutral	0.255
LRP5	O75197-1.2	R1190Q	Neutral	0.028
LRP5	O75197-1.2	R1190S	Neutral	0.177
LRP5	O75197-1.2	R1190T	Neutral	0.146
LRP5	O75197-1.2	R1190V	Neutral	0.406
LRP5	O75197-1.2	R1190W	Neutral	0.221
LRP5	O75197-1.2	R1190Y	Neutral	0.23
LRP5	O75197-1.2	I1191A	Neutral	0.433
LRP5	O75197-1.2	I1191C	Pathogenic	0.59
LRP5	O75197-1.2	I1191D	Pathogenic	0.737
LRP5	O75197-1.2	I1191E	Pathogenic	0.764
LRP5	O75197-1.2	I1191F	Pathogenic	0.504
LRP5	O75197-1.2	I1191G	Pathogenic	0.941
LRP5	O75197-1.2	I1191H	Pathogenic	0.868
LRP5	O75197-1.2	I1191K	Pathogenic	0.705
LRP5	O75197-1.2	I1191L	Neutral	0.094
LRP5	O75197-1.2	I1191M	Neutral	0.171
LRP5	O75197-1.2	I1191N	Pathogenic	0.767
LRP5	O75197-1.2	I1191P	Pathogenic	0.914
LRP5	O75197-1.2	I1191Q	Pathogenic	0.826
LRP5	O75197-1.2	I1191R	Pathogenic	0.697
LRP5	O75197-1.2	I1191S	Pathogenic	0.633
LRP5	O75197-1.2	I1191T	Neutral	0.432
LRP5	O75197-1.2	I1191V	Neutral	0.021
LRP5	O75197-1.2	I1191W	Pathogenic	0.949
LRP5	O75197-1.2	I1191Y	Pathogenic	0.593
LRP5	O75197-1.2	Q1192A	Pathogenic	0.955
LRP5	O75197-1.2	Q1192C	Pathogenic	0.991
LRP5	O75197-1.2	Q1192D	Pathogenic	0.875
LRP5	O75197-1.2	Q1192E	Neutral	0.468
LRP5	O75197-1.2	Q1192F	Pathogenic	0.982
LRP5	O75197-1.2	Q1192G	Pathogenic	0.988
LRP5	O75197-1.2	Q1192H	Pathogenic	0.896
LRP5	O75197-1.2	Q1192I	Pathogenic	0.982
LRP5	O75197-1.2	Q1192K	Pathogenic	0.656
LRP5	O75197-1.2	Q1192L	Pathogenic	0.951
LRP5	O75197-1.2	Q1192M	Pathogenic	0.762
LRP5	O75197-1.2	Q1192N	Pathogenic	0.892
LRP5	O75197-1.2	Q1192P	Pathogenic	0.938
LRP5	O75197-1.2	Q1192R	Pathogenic	0.648
LRP5	O75197-1.2	Q1192S	Pathogenic	0.905
LRP5	O75197-1.2	Q1192T	Pathogenic	0.958
LRP5	O75197-1.2	Q1192V	Pathogenic	0.968
LRP5	O75197-1.2	Q1192W	Pathogenic	0.918
LRP5	O75197-1.2	Q1192Y	Pathogenic	0.924
LRP5	O75197-1.2	G1193A	Neutral	0.147
LRP5	O75197-1.2	G1193C	Pathogenic	0.72
LRP5	O75197-1.2	G1193D	Neutral	0.25
LRP5	O75197-1.2	G1193E	Pathogenic	0.526
LRP5	O75197-1.2	G1193F	Pathogenic	0.536
LRP5	O75197-1.2	G1193H	Pathogenic	0.632
LRP5	O75197-1.2	G1193I	Pathogenic	0.78
LRP5	O75197-1.2	G1193K	Neutral	0.437
LRP5	O75197-1.2	G1193L	Pathogenic	0.795
LRP5	O75197-1.2	G1193M	Pathogenic	0.66
LRP5	O75197-1.2	G1193N	Neutral	0.112
LRP5	O75197-1.2	G1193P	Pathogenic	0.516
LRP5	O75197-1.2	G1193Q	Pathogenic	0.615
LRP5	O75197-1.2	G1193R	Neutral	0.429
LRP5	O75197-1.2	G1193S	Neutral	0.179
LRP5	O75197-1.2	G1193T	Pathogenic	0.616
LRP5	O75197-1.2	G1193V	Pathogenic	0.669
LRP5	O75197-1.2	G1193W	Neutral	0.194
LRP5	O75197-1.2	G1193Y	Pathogenic	0.706
LRP5	O75197-1.2	R1194A	Pathogenic	0.909
LRP5	O75197-1.2	R1194C	Pathogenic	0.981
LRP5	O75197-1.2	R1194D	Pathogenic	0.988
LRP5	O75197-1.2	R1194E	Pathogenic	0.891
LRP5	O75197-1.2	R1194F	Pathogenic	0.965
LRP5	O75197-1.2	R1194G	Pathogenic	0.975
LRP5	O75197-1.2	R1194H	Pathogenic	0.807
LRP5	O75197-1.2	R1194I	Pathogenic	0.964
LRP5	O75197-1.2	R1194K	Pathogenic	0.558
LRP5	O75197-1.2	R1194L	Pathogenic	0.905
LRP5	O75197-1.2	R1194M	Pathogenic	0.827
LRP5	O75197-1.2	R1194N	Pathogenic	0.886
LRP5	O75197-1.2	R1194P	Pathogenic	0.956
LRP5	O75197-1.2	R1194Q	Pathogenic	0.651
LRP5	O75197-1.2	R1194S	Pathogenic	0.932
LRP5	O75197-1.2	R1194T	Pathogenic	0.916
LRP5	O75197-1.2	R1194V	Pathogenic	0.978
LRP5	O75197-1.2	R1194W	Pathogenic	0.948
LRP5	O75197-1.2	R1194Y	Pathogenic	0.95
LRP5	O75197-1.2	V1195A	Neutral	0.149
LRP5	O75197-1.2	V1195C	Pathogenic	0.501
LRP5	O75197-1.2	V1195D	Pathogenic	0.662
LRP5	O75197-1.2	V1195E	Neutral	0.424
LRP5	O75197-1.2	V1195F	Neutral	0.422
LRP5	O75197-1.2	V1195G	Pathogenic	0.784
LRP5	O75197-1.2	V1195H	Pathogenic	0.815
LRP5	O75197-1.2	V1195I	Neutral	0.008
LRP5	O75197-1.2	V1195K	Neutral	0.34
LRP5	O75197-1.2	V1195L	Neutral	0.08
LRP5	O75197-1.2	V1195M	Neutral	0.117
LRP5	O75197-1.2	V1195N	Pathogenic	0.697
LRP5	O75197-1.2	V1195P	Pathogenic	0.709
LRP5	O75197-1.2	V1195Q	Pathogenic	0.515
LRP5	O75197-1.2	V1195R	Pathogenic	0.602
LRP5	O75197-1.2	V1195S	Pathogenic	0.546
LRP5	O75197-1.2	V1195T	Neutral	0.149
LRP5	O75197-1.2	V1195W	Pathogenic	0.811
LRP5	O75197-1.2	V1195Y	Neutral	0.49
LRP5	O75197-1.2	A1196C	Neutral	0.189
LRP5	O75197-1.2	A1196D	Pathogenic	0.598
LRP5	O75197-1.2	A1196E	Neutral	0.349
LRP5	O75197-1.2	A1196F	Neutral	0.492
LRP5	O75197-1.2	A1196G	Neutral	0.244
LRP5	O75197-1.2	A1196H	Pathogenic	0.762
LRP5	O75197-1.2	A1196I	Neutral	0.242
LRP5	O75197-1.2	A1196K	Neutral	0.273
LRP5	O75197-1.2	A1196L	Neutral	0.259
LRP5	O75197-1.2	A1196M	Neutral	0.348
LRP5	O75197-1.2	A1196N	Pathogenic	0.632
LRP5	O75197-1.2	A1196P	Neutral	0.471
LRP5	O75197-1.2	A1196Q	Neutral	0.436
LRP5	O75197-1.2	A1196R	Neutral	0.266
LRP5	O75197-1.2	A1196S	Neutral	0.095
LRP5	O75197-1.2	A1196T	Neutral	0.287
LRP5	O75197-1.2	A1196V	Neutral	0.155
LRP5	O75197-1.2	A1196W	Pathogenic	0.651
LRP5	O75197-1.2	A1196Y	Pathogenic	0.668
LRP5	O75197-1.2	H1197A	Neutral	0.39
LRP5	O75197-1.2	H1197C	Pathogenic	0.523
LRP5	O75197-1.2	H1197D	Neutral	0.102
LRP5	O75197-1.2	H1197E	Neutral	0.042
LRP5	O75197-1.2	H1197F	Neutral	0.056
LRP5	O75197-1.2	H1197G	Neutral	0.392
LRP5	O75197-1.2	H1197I	Neutral	0.354
LRP5	O75197-1.2	H1197K	Neutral	0.087
LRP5	O75197-1.2	H1197L	Neutral	0.376
LRP5	O75197-1.2	H1197M	Neutral	0.231
LRP5	O75197-1.2	H1197N	Neutral	0.014
LRP5	O75197-1.2	H1197P	Neutral	0.315
LRP5	O75197-1.2	H1197Q	Neutral	0.06
LRP5	O75197-1.2	H1197R	Neutral	0.029
LRP5	O75197-1.2	H1197S	Neutral	0.176
LRP5	O75197-1.2	H1197T	Neutral	0.411
LRP5	O75197-1.2	H1197V	Neutral	0.478
LRP5	O75197-1.2	H1197W	Neutral	0.102
LRP5	O75197-1.2	H1197Y	Neutral	0.004
LRP5	O75197-1.2	L1198A	Pathogenic	0.917
LRP5	O75197-1.2	L1198C	Pathogenic	0.954
LRP5	O75197-1.2	L1198D	Pathogenic	0.992
LRP5	O75197-1.2	L1198E	Pathogenic	0.979
LRP5	O75197-1.2	L1198F	Pathogenic	0.926
LRP5	O75197-1.2	L1198G	Pathogenic	0.996
LRP5	O75197-1.2	L1198H	Pathogenic	0.99
LRP5	O75197-1.2	L1198I	Pathogenic	0.576
LRP5	O75197-1.2	L1198K	Pathogenic	0.919
LRP5	O75197-1.2	L1198M	Neutral	0.494
LRP5	O75197-1.2	L1198N	Pathogenic	0.979
LRP5	O75197-1.2	L1198P	Pathogenic	0.993
LRP5	O75197-1.2	L1198Q	Pathogenic	0.957
LRP5	O75197-1.2	L1198R	Pathogenic	0.916
LRP5	O75197-1.2	L1198S	Pathogenic	0.961
LRP5	O75197-1.2	L1198T	Pathogenic	0.916
LRP5	O75197-1.2	L1198V	Pathogenic	0.74
LRP5	O75197-1.2	L1198W	Pathogenic	0.987
LRP5	O75197-1.2	L1198Y	Pathogenic	0.955
LRP5	O75197-1.2	T1199A	Pathogenic	0.572
LRP5	O75197-1.2	T1199C	Pathogenic	0.696
LRP5	O75197-1.2	T1199D	Pathogenic	0.639
LRP5	O75197-1.2	T1199E	Pathogenic	0.66
LRP5	O75197-1.2	T1199F	Pathogenic	0.762
LRP5	O75197-1.2	T1199G	Pathogenic	0.909
LRP5	O75197-1.2	T1199H	Pathogenic	0.921
LRP5	O75197-1.2	T1199I	Pathogenic	0.514
LRP5	O75197-1.2	T1199K	Pathogenic	0.576
LRP5	O75197-1.2	T1199L	Pathogenic	0.537
LRP5	O75197-1.2	T1199M	Pathogenic	0.638
LRP5	O75197-1.2	T1199N	Neutral	0.403
LRP5	O75197-1.2	T1199P	Pathogenic	0.745
LRP5	O75197-1.2	T1199Q	Pathogenic	0.737
LRP5	O75197-1.2	T1199R	Pathogenic	0.568
LRP5	O75197-1.2	T1199S	Neutral	0.263
LRP5	O75197-1.2	T1199V	Neutral	0.377
LRP5	O75197-1.2	T1199W	Pathogenic	0.67
LRP5	O75197-1.2	T1199Y	Pathogenic	0.869
LRP5	O75197-1.2	G1200A	Neutral	0.147
LRP5	O75197-1.2	G1200C	Pathogenic	0.72
LRP5	O75197-1.2	G1200D	Neutral	0.25
LRP5	O75197-1.2	G1200E	Pathogenic	0.526
LRP5	O75197-1.2	G1200F	Pathogenic	0.536
LRP5	O75197-1.2	G1200H	Pathogenic	0.632
LRP5	O75197-1.2	G1200I	Pathogenic	0.779
LRP5	O75197-1.2	G1200K	Neutral	0.437
LRP5	O75197-1.2	G1200L	Pathogenic	0.795
LRP5	O75197-1.2	G1200M	Pathogenic	0.659
LRP5	O75197-1.2	G1200N	Neutral	0.112
LRP5	O75197-1.2	G1200P	Pathogenic	0.515
LRP5	O75197-1.2	G1200Q	Pathogenic	0.615
LRP5	O75197-1.2	G1200R	Neutral	0.429
LRP5	O75197-1.2	G1200S	Neutral	0.179
LRP5	O75197-1.2	G1200T	Pathogenic	0.615
LRP5	O75197-1.2	G1200V	Pathogenic	0.669
LRP5	O75197-1.2	G1200W	Neutral	0.194
LRP5	O75197-1.2	G1200Y	Pathogenic	0.706
LRP5	O75197-1.2	I1201A	Pathogenic	0.851
LRP5	O75197-1.2	I1201C	Pathogenic	0.915
LRP5	O75197-1.2	I1201D	Pathogenic	0.954
LRP5	O75197-1.2	I1201E	Pathogenic	0.96
LRP5	O75197-1.2	I1201F	Pathogenic	0.883
LRP5	O75197-1.2	I1201G	Pathogenic	0.992
LRP5	O75197-1.2	I1201H	Pathogenic	0.98
LRP5	O75197-1.2	I1201K	Pathogenic	0.947
LRP5	O75197-1.2	I1201L	Neutral	0.435
LRP5	O75197-1.2	I1201M	Pathogenic	0.606
LRP5	O75197-1.2	I1201N	Pathogenic	0.961
LRP5	O75197-1.2	I1201P	Pathogenic	0.987
LRP5	O75197-1.2	I1201Q	Pathogenic	0.973
LRP5	O75197-1.2	I1201R	Pathogenic	0.945
LRP5	O75197-1.2	I1201S	Pathogenic	0.928
LRP5	O75197-1.2	I1201T	Pathogenic	0.85
LRP5	O75197-1.2	I1201V	Neutral	0.137
LRP5	O75197-1.2	I1201W	Pathogenic	0.993
LRP5	O75197-1.2	I1201Y	Pathogenic	0.916
LRP5	O75197-1.2	H1202A	Pathogenic	0.993
LRP5	O75197-1.2	H1202C	Pathogenic	0.996
LRP5	O75197-1.2	H1202D	Pathogenic	0.961
LRP5	O75197-1.2	H1202E	Pathogenic	0.903
LRP5	O75197-1.2	H1202F	Pathogenic	0.927
LRP5	O75197-1.2	H1202G	Pathogenic	0.993
LRP5	O75197-1.2	H1202I	Pathogenic	0.992
LRP5	O75197-1.2	H1202K	Pathogenic	0.953
LRP5	O75197-1.2	H1202L	Pathogenic	0.992
LRP5	O75197-1.2	H1202M	Pathogenic	0.985
LRP5	O75197-1.2	H1202N	Pathogenic	0.756
LRP5	O75197-1.2	H1202P	Pathogenic	0.99
LRP5	O75197-1.2	H1202Q	Pathogenic	0.932
LRP5	O75197-1.2	H1202R	Pathogenic	0.866
LRP5	O75197-1.2	H1202S	Pathogenic	0.979
LRP5	O75197-1.2	H1202T	Pathogenic	0.993
LRP5	O75197-1.2	H1202V	Pathogenic	0.995
LRP5	O75197-1.2	H1202W	Pathogenic	0.96
LRP5	O75197-1.2	H1202Y	Neutral	0.482
LRP5	O75197-1.2	A1203C	Pathogenic	0.907
LRP5	O75197-1.2	A1203D	Pathogenic	0.984
LRP5	O75197-1.2	A1203E	Pathogenic	0.958
LRP5	O75197-1.2	A1203F	Pathogenic	0.976
LRP5	O75197-1.2	A1203G	Pathogenic	0.932
LRP5	O75197-1.2	A1203H	Pathogenic	0.993
LRP5	O75197-1.2	A1203I	Pathogenic	0.931
LRP5	O75197-1.2	A1203K	Pathogenic	0.94
LRP5	O75197-1.2	A1203L	Pathogenic	0.937
LRP5	O75197-1.2	A1203M	Pathogenic	0.957
LRP5	O75197-1.2	A1203N	Pathogenic	0.986
LRP5	O75197-1.2	A1203P	Pathogenic	0.974
LRP5	O75197-1.2	A1203Q	Pathogenic	0.97
LRP5	O75197-1.2	A1203R	Pathogenic	0.939
LRP5	O75197-1.2	A1203S	Pathogenic	0.815
LRP5	O75197-1.2	A1203T	Pathogenic	0.944
LRP5	O75197-1.2	A1203V	Pathogenic	0.885
LRP5	O75197-1.2	A1203W	Pathogenic	0.987
LRP5	O75197-1.2	A1203Y	Pathogenic	0.988
LRP5	O75197-1.2	V1204A	Pathogenic	0.815
LRP5	O75197-1.2	V1204C	Pathogenic	0.962
LRP5	O75197-1.2	V1204D	Pathogenic	0.98
LRP5	O75197-1.2	V1204E	Pathogenic	0.949
LRP5	O75197-1.2	V1204F	Pathogenic	0.948
LRP5	O75197-1.2	V1204G	Pathogenic	0.989
LRP5	O75197-1.2	V1204H	Pathogenic	0.991
LRP5	O75197-1.2	V1204I	Neutral	0.177
LRP5	O75197-1.2	V1204K	Pathogenic	0.928
LRP5	O75197-1.2	V1204L	Pathogenic	0.686
LRP5	O75197-1.2	V1204M	Pathogenic	0.769
LRP5	O75197-1.2	V1204N	Pathogenic	0.983
LRP5	O75197-1.2	V1204P	Pathogenic	0.984
LRP5	O75197-1.2	V1204Q	Pathogenic	0.964
LRP5	O75197-1.2	V1204R	Pathogenic	0.974
LRP5	O75197-1.2	V1204S	Pathogenic	0.968
LRP5	O75197-1.2	V1204T	Pathogenic	0.814
LRP5	O75197-1.2	V1204W	Pathogenic	0.991
LRP5	O75197-1.2	V1204Y	Pathogenic	0.96
LRP5	O75197-1.2	E1205A	Neutral	0.117
LRP5	O75197-1.2	E1205C	Pathogenic	0.677
LRP5	O75197-1.2	E1205D	Neutral	0.01
LRP5	O75197-1.2	E1205F	Neutral	0.25
LRP5	O75197-1.2	E1205G	Neutral	0.339
LRP5	O75197-1.2	E1205H	Neutral	0.051
LRP5	O75197-1.2	E1205I	Neutral	0.251
LRP5	O75197-1.2	E1205K	Neutral	0.024
LRP5	O75197-1.2	E1205L	Neutral	0.268
LRP5	O75197-1.2	E1205M	Neutral	0.155
LRP5	O75197-1.2	E1205N	Neutral	0.093
LRP5	O75197-1.2	E1205P	Neutral	0.087
LRP5	O75197-1.2	E1205Q	Neutral	0.008
LRP5	O75197-1.2	E1205R	Neutral	0.068
LRP5	O75197-1.2	E1205S	Neutral	0.056
LRP5	O75197-1.2	E1205T	Neutral	0.126
LRP5	O75197-1.2	E1205V	Neutral	0.159
LRP5	O75197-1.2	E1205W	Neutral	0.174
LRP5	O75197-1.2	E1205Y	Neutral	0.185
LRP5	O75197-1.2	E1206A	Neutral	0.135
LRP5	O75197-1.2	E1206C	Pathogenic	0.712
LRP5	O75197-1.2	E1206D	Neutral	0.012
LRP5	O75197-1.2	E1206F	Neutral	0.282
LRP5	O75197-1.2	E1206G	Neutral	0.377
LRP5	O75197-1.2	E1206H	Neutral	0.059
LRP5	O75197-1.2	E1206I	Neutral	0.283
LRP5	O75197-1.2	E1206K	Neutral	0.029
LRP5	O75197-1.2	E1206L	Neutral	0.302
LRP5	O75197-1.2	E1206M	Neutral	0.178
LRP5	O75197-1.2	E1206N	Neutral	0.108
LRP5	O75197-1.2	E1206P	Neutral	0.101
LRP5	O75197-1.2	E1206Q	Neutral	0.009
LRP5	O75197-1.2	E1206R	Neutral	0.08
LRP5	O75197-1.2	E1206S	Neutral	0.066
LRP5	O75197-1.2	E1206T	Neutral	0.145
LRP5	O75197-1.2	E1206V	Neutral	0.183
LRP5	O75197-1.2	E1206W	Neutral	0.199
LRP5	O75197-1.2	E1206Y	Neutral	0.212
LRP5	O75197-1.2	V1207A	Neutral	0.004
LRP5	O75197-1.2	V1207C	Neutral	0.022
LRP5	O75197-1.2	V1207D	Neutral	0.042
LRP5	O75197-1.2	V1207E	Neutral	0.016
LRP5	O75197-1.2	V1207F	Neutral	0.016
LRP5	O75197-1.2	V1207G	Neutral	0.076
LRP5	O75197-1.2	V1207H	Neutral	0.09
LRP5	O75197-1.2	V1207I	Neutral	0.0
LRP5	O75197-1.2	V1207K	Neutral	0.011
LRP5	O75197-1.2	V1207L	Neutral	0.002
LRP5	O75197-1.2	V1207M	Neutral	0.003
LRP5	O75197-1.2	V1207N	Neutral	0.049
LRP5	O75197-1.2	V1207P	Neutral	0.052
LRP5	O75197-1.2	V1207Q	Neutral	0.023
LRP5	O75197-1.2	V1207R	Neutral	0.033
LRP5	O75197-1.2	V1207S	Neutral	0.026
LRP5	O75197-1.2	V1207T	Neutral	0.004
LRP5	O75197-1.2	V1207W	Neutral	0.088
LRP5	O75197-1.2	V1207Y	Neutral	0.021
LRP5	O75197-1.2	S1208A	Neutral	0.003
LRP5	O75197-1.2	S1208C	Neutral	0.013
LRP5	O75197-1.2	S1208D	Neutral	0.005
LRP5	O75197-1.2	S1208E	Neutral	0.006
LRP5	O75197-1.2	S1208F	Neutral	0.017
LRP5	O75197-1.2	S1208G	Neutral	0.01
LRP5	O75197-1.2	S1208H	Neutral	0.026
LRP5	O75197-1.2	S1208I	Neutral	0.017
LRP5	O75197-1.2	S1208K	Neutral	0.004
LRP5	O75197-1.2	S1208L	Neutral	0.019
LRP5	O75197-1.2	S1208M	Neutral	0.01
LRP5	O75197-1.2	S1208N	Neutral	0.002
LRP5	O75197-1.2	S1208P	Neutral	0.016
LRP5	O75197-1.2	S1208Q	Neutral	0.008
LRP5	O75197-1.2	S1208R	Neutral	0.012
LRP5	O75197-1.2	S1208T	Neutral	0.003
LRP5	O75197-1.2	S1208V	Neutral	0.03
LRP5	O75197-1.2	S1208W	Neutral	0.033
LRP5	O75197-1.2	S1208Y	Neutral	0.035
LRP5	O75197-1.2	L1209A	Neutral	0.016
LRP5	O75197-1.2	L1209C	Neutral	0.03
LRP5	O75197-1.2	L1209D	Neutral	0.156
LRP5	O75197-1.2	L1209E	Neutral	0.066
LRP5	O75197-1.2	L1209F	Neutral	0.019
LRP5	O75197-1.2	L1209G	Neutral	0.256
LRP5	O75197-1.2	L1209H	Neutral	0.125
LRP5	O75197-1.2	L1209I	Neutral	0.002
LRP5	O75197-1.2	L1209K	Neutral	0.017
LRP5	O75197-1.2	L1209M	Neutral	0.001
LRP5	O75197-1.2	L1209N	Neutral	0.067
LRP5	O75197-1.2	L1209P	Neutral	0.187
LRP5	O75197-1.2	L1209Q	Neutral	0.033
LRP5	O75197-1.2	L1209R	Neutral	0.016
LRP5	O75197-1.2	L1209S	Neutral	0.036
LRP5	O75197-1.2	L1209T	Neutral	0.016
LRP5	O75197-1.2	L1209V	Neutral	0.004
LRP5	O75197-1.2	L1209W	Neutral	0.099
LRP5	O75197-1.2	L1209Y	Neutral	0.031
LRP5	O75197-1.2	E1210A	Neutral	0.013
LRP5	O75197-1.2	E1210C	Neutral	0.168
LRP5	O75197-1.2	E1210D	Neutral	0.001
LRP5	O75197-1.2	E1210F	Neutral	0.031
LRP5	O75197-1.2	E1210G	Neutral	0.047
LRP5	O75197-1.2	E1210H	Neutral	0.005
LRP5	O75197-1.2	E1210I	Neutral	0.031
LRP5	O75197-1.2	E1210K	Neutral	0.002
LRP5	O75197-1.2	E1210L	Neutral	0.034
LRP5	O75197-1.2	E1210M	Neutral	0.017
LRP5	O75197-1.2	E1210N	Neutral	0.01
LRP5	O75197-1.2	E1210P	Neutral	0.009
LRP5	O75197-1.2	E1210Q	Neutral	0.001
LRP5	O75197-1.2	E1210R	Neutral	0.007
LRP5	O75197-1.2	E1210S	Neutral	0.006
LRP5	O75197-1.2	E1210T	Neutral	0.014
LRP5	O75197-1.2	E1210V	Neutral	0.018
LRP5	O75197-1.2	E1210W	Neutral	0.02
LRP5	O75197-1.2	E1210Y	Neutral	0.022
LRP5	O75197-1.2	E1211A	Pathogenic	0.693
LRP5	O75197-1.2	E1211C	Pathogenic	0.973
LRP5	O75197-1.2	E1211D	Neutral	0.147
LRP5	O75197-1.2	E1211F	Pathogenic	0.851
LRP5	O75197-1.2	E1211G	Pathogenic	0.898
LRP5	O75197-1.2	E1211H	Neutral	0.478
LRP5	O75197-1.2	E1211I	Pathogenic	0.851
LRP5	O75197-1.2	E1211K	Neutral	0.299
LRP5	O75197-1.2	E1211L	Pathogenic	0.863
LRP5	O75197-1.2	E1211M	Pathogenic	0.759
LRP5	O75197-1.2	E1211N	Pathogenic	0.637
LRP5	O75197-1.2	E1211P	Pathogenic	0.619
LRP5	O75197-1.2	E1211Q	Neutral	0.12
LRP5	O75197-1.2	E1211R	Pathogenic	0.556
LRP5	O75197-1.2	E1211S	Pathogenic	0.505
LRP5	O75197-1.2	E1211T	Pathogenic	0.712
LRP5	O75197-1.2	E1211V	Pathogenic	0.764
LRP5	O75197-1.2	E1211W	Pathogenic	0.783
LRP5	O75197-1.2	E1211Y	Pathogenic	0.796
LRP5	O75197-1.2	F1212A	Neutral	0.47
LRP5	O75197-1.2	F1212C	Pathogenic	0.626
LRP5	O75197-1.2	F1212D	Pathogenic	0.517
LRP5	O75197-1.2	F1212E	Pathogenic	0.553
LRP5	O75197-1.2	F1212G	Pathogenic	0.665
LRP5	O75197-1.2	F1212H	Neutral	0.213
LRP5	O75197-1.2	F1212I	Neutral	0.28
LRP5	O75197-1.2	F1212K	Neutral	0.485
LRP5	O75197-1.2	F1212L	Neutral	0.267
LRP5	O75197-1.2	F1212M	Neutral	0.193
LRP5	O75197-1.2	F1212N	Pathogenic	0.556
LRP5	O75197-1.2	F1212P	Pathogenic	0.925
LRP5	O75197-1.2	F1212Q	Pathogenic	0.645
LRP5	O75197-1.2	F1212R	Neutral	0.477
LRP5	O75197-1.2	F1212S	Neutral	0.397
LRP5	O75197-1.2	F1212T	Neutral	0.469
LRP5	O75197-1.2	F1212V	Neutral	0.411
LRP5	O75197-1.2	F1212W	Neutral	0.077
LRP5	O75197-1.2	F1212Y	Neutral	0.007
LRP5	O75197-1.2	S1213A	Neutral	0.0
LRP5	O75197-1.2	S1213C	Neutral	0.0
LRP5	O75197-1.2	S1213D	Neutral	0.0
LRP5	O75197-1.2	S1213E	Neutral	0.0
LRP5	O75197-1.2	S1213F	Neutral	0.0
LRP5	O75197-1.2	S1213G	Neutral	0.0
LRP5	O75197-1.2	S1213H	Neutral	0.0
LRP5	O75197-1.2	S1213I	Neutral	0.0
LRP5	O75197-1.2	S1213K	Neutral	0.0
LRP5	O75197-1.2	S1213L	Neutral	0.0
LRP5	O75197-1.2	S1213M	Neutral	0.0
LRP5	O75197-1.2	S1213N	Neutral	0.0
LRP5	O75197-1.2	S1213P	Neutral	0.0
LRP5	O75197-1.2	S1213Q	Neutral	0.0
LRP5	O75197-1.2	S1213R	Neutral	0.0
LRP5	O75197-1.2	S1213T	Neutral	0.0
LRP5	O75197-1.2	S1213V	Neutral	0.0
LRP5	O75197-1.2	S1213W	Neutral	0.0
LRP5	O75197-1.2	S1213Y	Neutral	0.0
LRP5	O75197-1.2	A1214C	Neutral	0.0
LRP5	O75197-1.2	A1214D	Neutral	0.0
LRP5	O75197-1.2	A1214E	Neutral	0.0
LRP5	O75197-1.2	A1214F	Neutral	0.0
LRP5	O75197-1.2	A1214G	Neutral	0.0
LRP5	O75197-1.2	A1214H	Neutral	0.0
LRP5	O75197-1.2	A1214I	Neutral	0.0
LRP5	O75197-1.2	A1214K	Neutral	0.0
LRP5	O75197-1.2	A1214L	Neutral	0.0
LRP5	O75197-1.2	A1214M	Neutral	0.0
LRP5	O75197-1.2	A1214N	Neutral	0.0
LRP5	O75197-1.2	A1214P	Neutral	0.0
LRP5	O75197-1.2	A1214Q	Neutral	0.0
LRP5	O75197-1.2	A1214R	Neutral	0.0
LRP5	O75197-1.2	A1214S	Neutral	0.0
LRP5	O75197-1.2	A1214T	Neutral	0.0
LRP5	O75197-1.2	A1214V	Neutral	0.0
LRP5	O75197-1.2	A1214W	Neutral	0.0
LRP5	O75197-1.2	A1214Y	Neutral	0.0
LRP5	O75197-1.2	H1215A	Pathogenic	0.728
LRP5	O75197-1.2	H1215C	Pathogenic	0.821
LRP5	O75197-1.2	H1215D	Neutral	0.324
LRP5	O75197-1.2	H1215E	Neutral	0.154
LRP5	O75197-1.2	H1215F	Neutral	0.198
LRP5	O75197-1.2	H1215G	Pathogenic	0.73
LRP5	O75197-1.2	H1215I	Pathogenic	0.697
LRP5	O75197-1.2	H1215K	Neutral	0.285
LRP5	O75197-1.2	H1215L	Pathogenic	0.716
LRP5	O75197-1.2	H1215M	Pathogenic	0.558
LRP5	O75197-1.2	H1215N	Neutral	0.057
LRP5	O75197-1.2	H1215P	Pathogenic	0.658
LRP5	O75197-1.2	H1215Q	Neutral	0.211
LRP5	O75197-1.2	H1215R	Neutral	0.113
LRP5	O75197-1.2	H1215S	Neutral	0.472
LRP5	O75197-1.2	H1215T	Pathogenic	0.745
LRP5	O75197-1.2	H1215V	Pathogenic	0.794
LRP5	O75197-1.2	H1215W	Neutral	0.323
LRP5	O75197-1.2	H1215Y	Neutral	0.018
LRP5	O75197-1.2	P1216A	Neutral	0.058
LRP5	O75197-1.2	P1216C	Neutral	0.403
LRP5	O75197-1.2	P1216D	Neutral	0.024
LRP5	O75197-1.2	P1216E	Neutral	0.026
LRP5	O75197-1.2	P1216F	Neutral	0.483
LRP5	O75197-1.2	P1216G	Neutral	0.122
LRP5	O75197-1.2	P1216H	Neutral	0.138
LRP5	O75197-1.2	P1216I	Neutral	0.236
LRP5	O75197-1.2	P1216K	Neutral	0.018
LRP5	O75197-1.2	P1216L	Neutral	0.253
LRP5	O75197-1.2	P1216M	Neutral	0.145
LRP5	O75197-1.2	P1216N	Neutral	0.079
LRP5	O75197-1.2	P1216Q	Neutral	0.037
LRP5	O75197-1.2	P1216R	Neutral	0.052
LRP5	O75197-1.2	P1216S	Neutral	0.044
LRP5	O75197-1.2	P1216T	Neutral	0.058
LRP5	O75197-1.2	P1216V	Neutral	0.15
LRP5	O75197-1.2	P1216W	Neutral	0.372
LRP5	O75197-1.2	P1216Y	Neutral	0.39
LRP5	O75197-1.2	C1217A	Pathogenic	0.993
LRP5	O75197-1.2	C1217D	Pathogenic	0.999
LRP5	O75197-1.2	C1217E	Pathogenic	1.0
LRP5	O75197-1.2	C1217F	Pathogenic	0.999
LRP5	O75197-1.2	C1217G	Pathogenic	1.0
LRP5	O75197-1.2	C1217H	Pathogenic	1.0
LRP5	O75197-1.2	C1217I	Pathogenic	0.997
LRP5	O75197-1.2	C1217K	Pathogenic	0.999
LRP5	O75197-1.2	C1217L	Pathogenic	0.998
LRP5	O75197-1.2	C1217M	Pathogenic	0.998
LRP5	O75197-1.2	C1217N	Pathogenic	0.999
LRP5	O75197-1.2	C1217P	Pathogenic	1.0
LRP5	O75197-1.2	C1217Q	Pathogenic	1.0
LRP5	O75197-1.2	C1217R	Pathogenic	0.999
LRP5	O75197-1.2	C1217S	Pathogenic	0.997
LRP5	O75197-1.2	C1217T	Pathogenic	0.998
LRP5	O75197-1.2	C1217V	Pathogenic	0.999
LRP5	O75197-1.2	C1217W	Pathogenic	0.999
LRP5	O75197-1.2	C1217Y	Pathogenic	1.0
LRP5	O75197-1.2	A1218C	Neutral	0.0
LRP5	O75197-1.2	A1218D	Neutral	0.001
LRP5	O75197-1.2	A1218E	Neutral	0.001
LRP5	O75197-1.2	A1218F	Neutral	0.001
LRP5	O75197-1.2	A1218G	Neutral	0.0
LRP5	O75197-1.2	A1218H	Neutral	0.003
LRP5	O75197-1.2	A1218I	Neutral	0.0
LRP5	O75197-1.2	A1218K	Neutral	0.0
LRP5	O75197-1.2	A1218L	Neutral	0.0
LRP5	O75197-1.2	A1218M	Neutral	0.001
LRP5	O75197-1.2	A1218N	Neutral	0.002
LRP5	O75197-1.2	A1218P	Neutral	0.001
LRP5	O75197-1.2	A1218Q	Neutral	0.001
LRP5	O75197-1.2	A1218R	Neutral	0.0
LRP5	O75197-1.2	A1218S	Neutral	0.0
LRP5	O75197-1.2	A1218T	Neutral	0.0
LRP5	O75197-1.2	A1218V	Neutral	0.0
LRP5	O75197-1.2	A1218W	Neutral	0.002
LRP5	O75197-1.2	A1218Y	Neutral	0.002
LRP5	O75197-1.2	R1219A	Neutral	0.0
LRP5	O75197-1.2	R1219C	Neutral	0.0
LRP5	O75197-1.2	R1219D	Neutral	0.0
LRP5	O75197-1.2	R1219E	Neutral	0.0
LRP5	O75197-1.2	R1219F	Neutral	0.0
LRP5	O75197-1.2	R1219G	Neutral	0.0
LRP5	O75197-1.2	R1219H	Neutral	0.0
LRP5	O75197-1.2	R1219I	Neutral	0.0
LRP5	O75197-1.2	R1219K	Neutral	0.0
LRP5	O75197-1.2	R1219L	Neutral	0.0
LRP5	O75197-1.2	R1219M	Neutral	0.0
LRP5	O75197-1.2	R1219N	Neutral	0.0
LRP5	O75197-1.2	R1219P	Neutral	0.0
LRP5	O75197-1.2	R1219Q	Neutral	0.0
LRP5	O75197-1.2	R1219S	Neutral	0.0
LRP5	O75197-1.2	R1219T	Neutral	0.0
LRP5	O75197-1.2	R1219V	Neutral	0.0
LRP5	O75197-1.2	R1219W	Neutral	0.0
LRP5	O75197-1.2	R1219Y	Neutral	0.0
LRP5	O75197-1.2	D1220A	Neutral	0.033
LRP5	O75197-1.2	D1220C	Neutral	0.056
LRP5	O75197-1.2	D1220E	Neutral	0.001
LRP5	O75197-1.2	D1220F	Neutral	0.026
LRP5	O75197-1.2	D1220G	Neutral	0.014
LRP5	O75197-1.2	D1220H	Neutral	0.013
LRP5	O75197-1.2	D1220I	Neutral	0.027
LRP5	O75197-1.2	D1220K	Neutral	0.023
LRP5	O75197-1.2	D1220L	Neutral	0.083
LRP5	O75197-1.2	D1220M	Neutral	0.043
LRP5	O75197-1.2	D1220N	Neutral	0.003
LRP5	O75197-1.2	D1220P	Neutral	0.008
LRP5	O75197-1.2	D1220Q	Neutral	0.006
LRP5	O75197-1.2	D1220R	Neutral	0.065
LRP5	O75197-1.2	D1220S	Neutral	0.005
LRP5	O75197-1.2	D1220T	Neutral	0.012
LRP5	O75197-1.2	D1220V	Neutral	0.045
LRP5	O75197-1.2	D1220W	Neutral	0.05
LRP5	O75197-1.2	D1220Y	Neutral	0.053
LRP5	O75197-1.2	N1221A	Neutral	0.163
LRP5	O75197-1.2	N1221C	Neutral	0.25
LRP5	O75197-1.2	N1221D	Neutral	0.014
LRP5	O75197-1.2	N1221E	Neutral	0.045
LRP5	O75197-1.2	N1221F	Neutral	0.134
LRP5	O75197-1.2	N1221G	Neutral	0.026
LRP5	O75197-1.2	N1221H	Neutral	0.008
LRP5	O75197-1.2	N1221I	Neutral	0.135
LRP5	O75197-1.2	N1221K	Neutral	0.032
LRP5	O75197-1.2	N1221L	Neutral	0.146
LRP5	O75197-1.2	N1221M	Neutral	0.079
LRP5	O75197-1.2	N1221P	Neutral	0.123
LRP5	O75197-1.2	N1221Q	Neutral	0.033
LRP5	O75197-1.2	N1221R	Neutral	0.031
LRP5	O75197-1.2	N1221S	Neutral	0.009
LRP5	O75197-1.2	N1221T	Neutral	0.022
LRP5	O75197-1.2	N1221V	Neutral	0.213
LRP5	O75197-1.2	N1221W	Neutral	0.23
LRP5	O75197-1.2	N1221Y	Neutral	0.096
LRP5	O75197-1.2	G1222A	Neutral	0.025
LRP5	O75197-1.2	G1222C	Neutral	0.279
LRP5	O75197-1.2	G1222D	Neutral	0.048
LRP5	O75197-1.2	G1222E	Neutral	0.143
LRP5	O75197-1.2	G1222F	Neutral	0.148
LRP5	O75197-1.2	G1222H	Neutral	0.205
LRP5	O75197-1.2	G1222I	Neutral	0.347
LRP5	O75197-1.2	G1222K	Neutral	0.105
LRP5	O75197-1.2	G1222L	Neutral	0.368
LRP5	O75197-1.2	G1222M	Neutral	0.225
LRP5	O75197-1.2	G1222N	Neutral	0.019
LRP5	O75197-1.2	G1222P	Neutral	0.138
LRP5	O75197-1.2	G1222Q	Neutral	0.194
LRP5	O75197-1.2	G1222R	Neutral	0.101
LRP5	O75197-1.2	G1222S	Neutral	0.032
LRP5	O75197-1.2	G1222T	Neutral	0.194
LRP5	O75197-1.2	G1222V	Neutral	0.233
LRP5	O75197-1.2	G1222W	Neutral	0.035
LRP5	O75197-1.2	G1222Y	Neutral	0.265
LRP5	O75197-1.2	G1223A	Neutral	0.04
LRP5	O75197-1.2	G1223C	Neutral	0.383
LRP5	O75197-1.2	G1223D	Neutral	0.074
LRP5	O75197-1.2	G1223E	Neutral	0.211
LRP5	O75197-1.2	G1223F	Neutral	0.218
LRP5	O75197-1.2	G1223H	Neutral	0.293
LRP5	O75197-1.2	G1223I	Neutral	0.46
LRP5	O75197-1.2	G1223K	Neutral	0.158
LRP5	O75197-1.2	G1223L	Neutral	0.483
LRP5	O75197-1.2	G1223M	Neutral	0.318
LRP5	O75197-1.2	G1223N	Neutral	0.03
LRP5	O75197-1.2	G1223P	Neutral	0.204
LRP5	O75197-1.2	G1223Q	Neutral	0.278
LRP5	O75197-1.2	G1223R	Neutral	0.153
LRP5	O75197-1.2	G1223S	Neutral	0.05
LRP5	O75197-1.2	G1223T	Neutral	0.278
LRP5	O75197-1.2	G1223V	Neutral	0.328
LRP5	O75197-1.2	G1223W	Neutral	0.055
LRP5	O75197-1.2	G1223Y	Neutral	0.366
LRP5	O75197-1.2	C1224A	Pathogenic	0.993
LRP5	O75197-1.2	C1224D	Pathogenic	0.999
LRP5	O75197-1.2	C1224E	Pathogenic	1.0
LRP5	O75197-1.2	C1224F	Pathogenic	0.999
LRP5	O75197-1.2	C1224G	Pathogenic	1.0
LRP5	O75197-1.2	C1224H	Pathogenic	1.0
LRP5	O75197-1.2	C1224I	Pathogenic	0.997
LRP5	O75197-1.2	C1224K	Pathogenic	0.999
LRP5	O75197-1.2	C1224L	Pathogenic	0.998
LRP5	O75197-1.2	C1224M	Pathogenic	0.998
LRP5	O75197-1.2	C1224N	Pathogenic	0.999
LRP5	O75197-1.2	C1224P	Pathogenic	1.0
LRP5	O75197-1.2	C1224Q	Pathogenic	1.0
LRP5	O75197-1.2	C1224R	Pathogenic	0.999
LRP5	O75197-1.2	C1224S	Pathogenic	0.997
LRP5	O75197-1.2	C1224T	Pathogenic	0.998
LRP5	O75197-1.2	C1224V	Pathogenic	0.999
LRP5	O75197-1.2	C1224W	Pathogenic	0.999
LRP5	O75197-1.2	C1224Y	Pathogenic	1.0
LRP5	O75197-1.2	S1225A	Neutral	0.016
LRP5	O75197-1.2	S1225C	Neutral	0.074
LRP5	O75197-1.2	S1225D	Neutral	0.033
LRP5	O75197-1.2	S1225E	Neutral	0.036
LRP5	O75197-1.2	S1225F	Neutral	0.099
LRP5	O75197-1.2	S1225G	Neutral	0.059
LRP5	O75197-1.2	S1225H	Neutral	0.141
LRP5	O75197-1.2	S1225I	Neutral	0.1
LRP5	O75197-1.2	S1225K	Neutral	0.025
LRP5	O75197-1.2	S1225L	Neutral	0.108
LRP5	O75197-1.2	S1225M	Neutral	0.057
LRP5	O75197-1.2	S1225N	Neutral	0.013
LRP5	O75197-1.2	S1225P	Neutral	0.092
LRP5	O75197-1.2	S1225Q	Neutral	0.051
LRP5	O75197-1.2	S1225R	Neutral	0.071
LRP5	O75197-1.2	S1225T	Neutral	0.016
LRP5	O75197-1.2	S1225V	Neutral	0.161
LRP5	O75197-1.2	S1225W	Neutral	0.175
LRP5	O75197-1.2	S1225Y	Neutral	0.186
LRP5	O75197-1.2	H1226A	Pathogenic	0.833
LRP5	O75197-1.2	H1226C	Pathogenic	0.895
LRP5	O75197-1.2	H1226D	Neutral	0.471
LRP5	O75197-1.2	H1226E	Neutral	0.253
LRP5	O75197-1.2	H1226F	Neutral	0.315
LRP5	O75197-1.2	H1226G	Pathogenic	0.834
LRP5	O75197-1.2	H1226I	Pathogenic	0.811
LRP5	O75197-1.2	H1226K	Neutral	0.426
LRP5	O75197-1.2	H1226L	Pathogenic	0.824
LRP5	O75197-1.2	H1226M	Pathogenic	0.701
LRP5	O75197-1.2	H1226N	Neutral	0.101
LRP5	O75197-1.2	H1226P	Pathogenic	0.782
LRP5	O75197-1.2	H1226Q	Neutral	0.332
LRP5	O75197-1.2	H1226R	Neutral	0.191
LRP5	O75197-1.2	H1226S	Pathogenic	0.625
LRP5	O75197-1.2	H1226T	Pathogenic	0.845
LRP5	O75197-1.2	H1226V	Pathogenic	0.877
LRP5	O75197-1.2	H1226W	Neutral	0.47
LRP5	O75197-1.2	H1226Y	Neutral	0.033
LRP5	O75197-1.2	I1227A	Neutral	0.015
LRP5	O75197-1.2	I1227C	Neutral	0.027
LRP5	O75197-1.2	I1227D	Neutral	0.052
LRP5	O75197-1.2	I1227E	Neutral	0.06
LRP5	O75197-1.2	I1227F	Neutral	0.019
LRP5	O75197-1.2	I1227G	Neutral	0.236
LRP5	O75197-1.2	I1227H	Neutral	0.113
LRP5	O75197-1.2	I1227K	Neutral	0.044
LRP5	O75197-1.2	I1227L	Neutral	0.002
LRP5	O75197-1.2	I1227M	Neutral	0.004
LRP5	O75197-1.2	I1227N	Neutral	0.06
LRP5	O75197-1.2	I1227P	Neutral	0.171
LRP5	O75197-1.2	I1227Q	Neutral	0.085
LRP5	O75197-1.2	I1227R	Neutral	0.043
LRP5	O75197-1.2	I1227S	Neutral	0.033
LRP5	O75197-1.2	I1227T	Neutral	0.015
LRP5	O75197-1.2	I1227V	Neutral	0.0
LRP5	O75197-1.2	I1227W	Neutral	0.266
LRP5	O75197-1.2	I1227Y	Neutral	0.028
LRP5	O75197-1.2	C1228A	Pathogenic	0.993
LRP5	O75197-1.2	C1228D	Pathogenic	0.999
LRP5	O75197-1.2	C1228E	Pathogenic	1.0
LRP5	O75197-1.2	C1228F	Pathogenic	0.999
LRP5	O75197-1.2	C1228G	Pathogenic	1.0
LRP5	O75197-1.2	C1228H	Pathogenic	1.0
LRP5	O75197-1.2	C1228I	Pathogenic	0.997
LRP5	O75197-1.2	C1228K	Pathogenic	0.999
LRP5	O75197-1.2	C1228L	Pathogenic	0.998
LRP5	O75197-1.2	C1228M	Pathogenic	0.998
LRP5	O75197-1.2	C1228N	Pathogenic	0.999
LRP5	O75197-1.2	C1228P	Pathogenic	1.0
LRP5	O75197-1.2	C1228Q	Pathogenic	1.0
LRP5	O75197-1.2	C1228R	Pathogenic	0.999
LRP5	O75197-1.2	C1228S	Pathogenic	0.997
LRP5	O75197-1.2	C1228T	Pathogenic	0.998
LRP5	O75197-1.2	C1228V	Pathogenic	0.999
LRP5	O75197-1.2	C1228W	Pathogenic	0.999
LRP5	O75197-1.2	C1228Y	Pathogenic	1.0
LRP5	O75197-1.2	I1229A	Neutral	0.002
LRP5	O75197-1.2	I1229C	Neutral	0.003
LRP5	O75197-1.2	I1229D	Neutral	0.006
LRP5	O75197-1.2	I1229E	Neutral	0.007
LRP5	O75197-1.2	I1229F	Neutral	0.002
LRP5	O75197-1.2	I1229G	Neutral	0.035
LRP5	O75197-1.2	I1229H	Neutral	0.015
LRP5	O75197-1.2	I1229K	Neutral	0.005
LRP5	O75197-1.2	I1229L	Neutral	0.0
LRP5	O75197-1.2	I1229M	Neutral	0.0
LRP5	O75197-1.2	I1229N	Neutral	0.007
LRP5	O75197-1.2	I1229P	Neutral	0.024
LRP5	O75197-1.2	I1229Q	Neutral	0.011
LRP5	O75197-1.2	I1229R	Neutral	0.005
LRP5	O75197-1.2	I1229S	Neutral	0.004
LRP5	O75197-1.2	I1229T	Neutral	0.002
LRP5	O75197-1.2	I1229V	Neutral	0.0
LRP5	O75197-1.2	I1229W	Neutral	0.041
LRP5	O75197-1.2	I1229Y	Neutral	0.003
LRP5	O75197-1.2	A1230C	Neutral	0.0
LRP5	O75197-1.2	A1230D	Neutral	0.002
LRP5	O75197-1.2	A1230E	Neutral	0.001
LRP5	O75197-1.2	A1230F	Neutral	0.001
LRP5	O75197-1.2	A1230G	Neutral	0.0
LRP5	O75197-1.2	A1230H	Neutral	0.003
LRP5	O75197-1.2	A1230I	Neutral	0.0
LRP5	O75197-1.2	A1230K	Neutral	0.0
LRP5	O75197-1.2	A1230L	Neutral	0.0
LRP5	O75197-1.2	A1230M	Neutral	0.001
LRP5	O75197-1.2	A1230N	Neutral	0.002
LRP5	O75197-1.2	A1230P	Neutral	0.001
LRP5	O75197-1.2	A1230Q	Neutral	0.001
LRP5	O75197-1.2	A1230R	Neutral	0.0
LRP5	O75197-1.2	A1230S	Neutral	0.0
LRP5	O75197-1.2	A1230T	Neutral	0.0
LRP5	O75197-1.2	A1230V	Neutral	0.0
LRP5	O75197-1.2	A1230W	Neutral	0.002
LRP5	O75197-1.2	A1230Y	Neutral	0.002
LRP5	O75197-1.2	K1231A	Neutral	0.012
LRP5	O75197-1.2	K1231C	Neutral	0.059
LRP5	O75197-1.2	K1231D	Neutral	0.032
LRP5	O75197-1.2	K1231E	Neutral	0.003
LRP5	O75197-1.2	K1231F	Neutral	0.032
LRP5	O75197-1.2	K1231G	Neutral	0.045
LRP5	O75197-1.2	K1231H	Neutral	0.015
LRP5	O75197-1.2	K1231I	Neutral	0.031
LRP5	O75197-1.2	K1231L	Neutral	0.011
LRP5	O75197-1.2	K1231M	Neutral	0.006
LRP5	O75197-1.2	K1231N	Neutral	0.009
LRP5	O75197-1.2	K1231P	Neutral	0.009
LRP5	O75197-1.2	K1231Q	Neutral	0.002
LRP5	O75197-1.2	K1231R	Neutral	0.001
LRP5	O75197-1.2	K1231S	Neutral	0.005
LRP5	O75197-1.2	K1231T	Neutral	0.013
LRP5	O75197-1.2	K1231V	Neutral	0.017
LRP5	O75197-1.2	K1231W	Neutral	0.021
LRP5	O75197-1.2	K1231Y	Neutral	0.022
LRP5	O75197-1.2	G1232A	Neutral	0.005
LRP5	O75197-1.2	G1232C	Neutral	0.076
LRP5	O75197-1.2	G1232D	Neutral	0.011
LRP5	O75197-1.2	G1232E	Neutral	0.034
LRP5	O75197-1.2	G1232F	Neutral	0.036
LRP5	O75197-1.2	G1232H	Neutral	0.052
LRP5	O75197-1.2	G1232I	Neutral	0.101
LRP5	O75197-1.2	G1232K	Neutral	0.024
LRP5	O75197-1.2	G1232L	Neutral	0.11
LRP5	O75197-1.2	G1232M	Neutral	0.058
LRP5	O75197-1.2	G1232N	Neutral	0.004
LRP5	O75197-1.2	G1232P	Neutral	0.033
LRP5	O75197-1.2	G1232Q	Neutral	0.049
LRP5	O75197-1.2	G1232R	Neutral	0.023
LRP5	O75197-1.2	G1232S	Neutral	0.007
LRP5	O75197-1.2	G1232T	Neutral	0.049
LRP5	O75197-1.2	G1232V	Neutral	0.061
LRP5	O75197-1.2	G1232W	Neutral	0.008
LRP5	O75197-1.2	G1232Y	Neutral	0.071
LRP5	O75197-1.2	D1233A	Neutral	0.055
LRP5	O75197-1.2	D1233C	Neutral	0.091
LRP5	O75197-1.2	D1233E	Neutral	0.002
LRP5	O75197-1.2	D1233F	Neutral	0.044
LRP5	O75197-1.2	D1233G	Neutral	0.024
LRP5	O75197-1.2	D1233H	Neutral	0.022
LRP5	O75197-1.2	D1233I	Neutral	0.044
LRP5	O75197-1.2	D1233K	Neutral	0.038
LRP5	O75197-1.2	D1233L	Neutral	0.132
LRP5	O75197-1.2	D1233M	Neutral	0.071
LRP5	O75197-1.2	D1233N	Neutral	0.005
LRP5	O75197-1.2	D1233P	Neutral	0.014
LRP5	O75197-1.2	D1233Q	Neutral	0.01
LRP5	O75197-1.2	D1233R	Neutral	0.105
LRP5	O75197-1.2	D1233S	Neutral	0.009
LRP5	O75197-1.2	D1233T	Neutral	0.02
LRP5	O75197-1.2	D1233V	Neutral	0.074
LRP5	O75197-1.2	D1233W	Neutral	0.081
LRP5	O75197-1.2	D1233Y	Neutral	0.087
LRP5	O75197-1.2	G1234A	Neutral	0.003
LRP5	O75197-1.2	G1234C	Neutral	0.043
LRP5	O75197-1.2	G1234D	Neutral	0.006
LRP5	O75197-1.2	G1234E	Neutral	0.019
LRP5	O75197-1.2	G1234F	Neutral	0.02
LRP5	O75197-1.2	G1234H	Neutral	0.029
LRP5	O75197-1.2	G1234I	Neutral	0.058
LRP5	O75197-1.2	G1234K	Neutral	0.013
LRP5	O75197-1.2	G1234L	Neutral	0.063
LRP5	O75197-1.2	G1234M	Neutral	0.033
LRP5	O75197-1.2	G1234N	Neutral	0.002
LRP5	O75197-1.2	G1234P	Neutral	0.018
LRP5	O75197-1.2	G1234Q	Neutral	0.027
LRP5	O75197-1.2	G1234R	Neutral	0.013
LRP5	O75197-1.2	G1234S	Neutral	0.004
LRP5	O75197-1.2	G1234T	Neutral	0.027
LRP5	O75197-1.2	G1234V	Neutral	0.034
LRP5	O75197-1.2	G1234W	Neutral	0.004
LRP5	O75197-1.2	G1234Y	Neutral	0.04
LRP5	O75197-1.2	T1235A	Neutral	0.004
LRP5	O75197-1.2	T1235C	Neutral	0.007
LRP5	O75197-1.2	T1235D	Neutral	0.005
LRP5	O75197-1.2	T1235E	Neutral	0.006
LRP5	O75197-1.2	T1235F	Neutral	0.009
LRP5	O75197-1.2	T1235G	Neutral	0.028
LRP5	O75197-1.2	T1235H	Neutral	0.032
LRP5	O75197-1.2	T1235I	Neutral	0.003
LRP5	O75197-1.2	T1235K	Neutral	0.004
LRP5	O75197-1.2	T1235L	Neutral	0.003
LRP5	O75197-1.2	T1235M	Neutral	0.005
LRP5	O75197-1.2	T1235N	Neutral	0.002
LRP5	O75197-1.2	T1235P	Neutral	0.008
LRP5	O75197-1.2	T1235Q	Neutral	0.008
LRP5	O75197-1.2	T1235R	Neutral	0.004
LRP5	O75197-1.2	T1235S	Neutral	0.001
LRP5	O75197-1.2	T1235V	Neutral	0.002
LRP5	O75197-1.2	T1235W	Neutral	0.006
LRP5	O75197-1.2	T1235Y	Neutral	0.019
LRP5	O75197-1.2	P1236A	Neutral	0.001
LRP5	O75197-1.2	P1236C	Neutral	0.016
LRP5	O75197-1.2	P1236D	Neutral	0.001
LRP5	O75197-1.2	P1236E	Neutral	0.001
LRP5	O75197-1.2	P1236F	Neutral	0.021
LRP5	O75197-1.2	P1236G	Neutral	0.003
LRP5	O75197-1.2	P1236H	Neutral	0.004
LRP5	O75197-1.2	P1236I	Neutral	0.007
LRP5	O75197-1.2	P1236K	Neutral	0.0
LRP5	O75197-1.2	P1236L	Neutral	0.008
LRP5	O75197-1.2	P1236M	Neutral	0.004
LRP5	O75197-1.2	P1236N	Neutral	0.002
LRP5	O75197-1.2	P1236Q	Neutral	0.001
LRP5	O75197-1.2	P1236R	Neutral	0.001
LRP5	O75197-1.2	P1236S	Neutral	0.001
LRP5	O75197-1.2	P1236T	Neutral	0.001
LRP5	O75197-1.2	P1236V	Neutral	0.004
LRP5	O75197-1.2	P1236W	Neutral	0.014
LRP5	O75197-1.2	P1236Y	Neutral	0.015
LRP5	O75197-1.2	R1237A	Neutral	0.049
LRP5	O75197-1.2	R1237C	Neutral	0.211
LRP5	O75197-1.2	R1237D	Neutral	0.298
LRP5	O75197-1.2	R1237E	Neutral	0.04
LRP5	O75197-1.2	R1237F	Neutral	0.123
LRP5	O75197-1.2	R1237G	Neutral	0.166
LRP5	O75197-1.2	R1237H	Neutral	0.021
LRP5	O75197-1.2	R1237I	Neutral	0.12
LRP5	O75197-1.2	R1237K	Neutral	0.006
LRP5	O75197-1.2	R1237L	Neutral	0.047
LRP5	O75197-1.2	R1237M	Neutral	0.024
LRP5	O75197-1.2	R1237N	Neutral	0.038
LRP5	O75197-1.2	R1237P	Neutral	0.101
LRP5	O75197-1.2	R1237Q	Neutral	0.009
LRP5	O75197-1.2	R1237S	Neutral	0.066
LRP5	O75197-1.2	R1237T	Neutral	0.053
LRP5	O75197-1.2	R1237V	Neutral	0.183
LRP5	O75197-1.2	R1237W	Neutral	0.085
LRP5	O75197-1.2	R1237Y	Neutral	0.089
LRP5	O75197-1.2	C1238A	Pathogenic	0.994
LRP5	O75197-1.2	C1238D	Pathogenic	0.999
LRP5	O75197-1.2	C1238E	Pathogenic	1.0
LRP5	O75197-1.2	C1238F	Pathogenic	0.999
LRP5	O75197-1.2	C1238G	Pathogenic	1.0
LRP5	O75197-1.2	C1238H	Pathogenic	1.0
LRP5	O75197-1.2	C1238I	Pathogenic	0.998
LRP5	O75197-1.2	C1238K	Pathogenic	0.999
LRP5	O75197-1.2	C1238L	Pathogenic	0.998
LRP5	O75197-1.2	C1238M	Pathogenic	0.999
LRP5	O75197-1.2	C1238N	Pathogenic	1.0
LRP5	O75197-1.2	C1238P	Pathogenic	1.0
LRP5	O75197-1.2	C1238Q	Pathogenic	1.0
LRP5	O75197-1.2	C1238R	Pathogenic	0.999
LRP5	O75197-1.2	C1238S	Pathogenic	0.997
LRP5	O75197-1.2	C1238T	Pathogenic	0.998
LRP5	O75197-1.2	C1238V	Pathogenic	0.999
LRP5	O75197-1.2	C1238W	Pathogenic	0.999
LRP5	O75197-1.2	C1238Y	Pathogenic	1.0
LRP5	O75197-1.2	S1239A	Neutral	0.021
LRP5	O75197-1.2	S1239C	Neutral	0.098
LRP5	O75197-1.2	S1239D	Neutral	0.044
LRP5	O75197-1.2	S1239E	Neutral	0.048
LRP5	O75197-1.2	S1239F	Neutral	0.129
LRP5	O75197-1.2	S1239G	Neutral	0.078
LRP5	O75197-1.2	S1239H	Neutral	0.181
LRP5	O75197-1.2	S1239I	Neutral	0.13
LRP5	O75197-1.2	S1239K	Neutral	0.034
LRP5	O75197-1.2	S1239L	Neutral	0.14
LRP5	O75197-1.2	S1239M	Neutral	0.076
LRP5	O75197-1.2	S1239N	Neutral	0.017
LRP5	O75197-1.2	S1239P	Neutral	0.12
LRP5	O75197-1.2	S1239Q	Neutral	0.067
LRP5	O75197-1.2	S1239R	Neutral	0.093
LRP5	O75197-1.2	S1239T	Neutral	0.022
LRP5	O75197-1.2	S1239V	Neutral	0.206
LRP5	O75197-1.2	S1239W	Neutral	0.222
LRP5	O75197-1.2	S1239Y	Neutral	0.236
LRP5	O75197-1.2	C1240A	Pathogenic	0.994
LRP5	O75197-1.2	C1240D	Pathogenic	0.999
LRP5	O75197-1.2	C1240E	Pathogenic	1.0
LRP5	O75197-1.2	C1240F	Pathogenic	0.999
LRP5	O75197-1.2	C1240G	Pathogenic	1.0
LRP5	O75197-1.2	C1240H	Pathogenic	1.0
LRP5	O75197-1.2	C1240I	Pathogenic	0.998
LRP5	O75197-1.2	C1240K	Pathogenic	0.999
LRP5	O75197-1.2	C1240L	Pathogenic	0.998
LRP5	O75197-1.2	C1240M	Pathogenic	0.999
LRP5	O75197-1.2	C1240N	Pathogenic	1.0
LRP5	O75197-1.2	C1240P	Pathogenic	1.0
LRP5	O75197-1.2	C1240Q	Pathogenic	1.0
LRP5	O75197-1.2	C1240R	Pathogenic	0.999
LRP5	O75197-1.2	C1240S	Pathogenic	0.997
LRP5	O75197-1.2	C1240T	Pathogenic	0.998
LRP5	O75197-1.2	C1240V	Pathogenic	0.999
LRP5	O75197-1.2	C1240W	Pathogenic	0.999
LRP5	O75197-1.2	C1240Y	Pathogenic	1.0
LRP5	O75197-1.2	P1241A	Neutral	0.249
LRP5	O75197-1.2	P1241C	Pathogenic	0.783
LRP5	O75197-1.2	P1241D	Neutral	0.116
LRP5	O75197-1.2	P1241E	Neutral	0.125
LRP5	O75197-1.2	P1241F	Pathogenic	0.833
LRP5	O75197-1.2	P1241G	Neutral	0.426
LRP5	O75197-1.2	P1241H	Neutral	0.46
LRP5	O75197-1.2	P1241I	Pathogenic	0.622
LRP5	O75197-1.2	P1241K	Neutral	0.091
LRP5	O75197-1.2	P1241L	Pathogenic	0.643
LRP5	O75197-1.2	P1241M	Neutral	0.474
LRP5	O75197-1.2	P1241N	Neutral	0.314
LRP5	O75197-1.2	P1241Q	Neutral	0.171
LRP5	O75197-1.2	P1241R	Neutral	0.227
LRP5	O75197-1.2	P1241S	Neutral	0.197
LRP5	O75197-1.2	P1241T	Neutral	0.246
LRP5	O75197-1.2	P1241V	Neutral	0.485
LRP5	O75197-1.2	P1241W	Pathogenic	0.759
LRP5	O75197-1.2	P1241Y	Pathogenic	0.773
LRP5	O75197-1.2	V1242A	Neutral	0.0
LRP5	O75197-1.2	V1242C	Neutral	0.0
LRP5	O75197-1.2	V1242D	Neutral	0.001
LRP5	O75197-1.2	V1242E	Neutral	0.0
LRP5	O75197-1.2	V1242F	Neutral	0.0
LRP5	O75197-1.2	V1242G	Neutral	0.001
LRP5	O75197-1.2	V1242H	Neutral	0.001
LRP5	O75197-1.2	V1242I	Neutral	0.0
LRP5	O75197-1.2	V1242K	Neutral	0.0
LRP5	O75197-1.2	V1242L	Neutral	0.0
LRP5	O75197-1.2	V1242M	Neutral	0.0
LRP5	O75197-1.2	V1242N	Neutral	0.001
LRP5	O75197-1.2	V1242P	Neutral	0.001
LRP5	O75197-1.2	V1242Q	Neutral	0.0
LRP5	O75197-1.2	V1242R	Neutral	0.0
LRP5	O75197-1.2	V1242S	Neutral	0.0
LRP5	O75197-1.2	V1242T	Neutral	0.0
LRP5	O75197-1.2	V1242W	Neutral	0.001
LRP5	O75197-1.2	V1242Y	Neutral	0.0
LRP5	O75197-1.2	H1243A	Neutral	0.254
LRP5	O75197-1.2	H1243C	Neutral	0.369
LRP5	O75197-1.2	H1243D	Neutral	0.057
LRP5	O75197-1.2	H1243E	Neutral	0.023
LRP5	O75197-1.2	H1243F	Neutral	0.03
LRP5	O75197-1.2	H1243G	Neutral	0.256
LRP5	O75197-1.2	H1243I	Neutral	0.226
LRP5	O75197-1.2	H1243K	Neutral	0.048
LRP5	O75197-1.2	H1243L	Neutral	0.242
LRP5	O75197-1.2	H1243M	Neutral	0.138
LRP5	O75197-1.2	H1243N	Neutral	0.008
LRP5	O75197-1.2	H1243P	Neutral	0.196
LRP5	O75197-1.2	H1243Q	Neutral	0.033
LRP5	O75197-1.2	H1243R	Neutral	0.016
LRP5	O75197-1.2	H1243S	Neutral	0.102
LRP5	O75197-1.2	H1243T	Neutral	0.271
LRP5	O75197-1.2	H1243V	Neutral	0.328
LRP5	O75197-1.2	H1243W	Neutral	0.057
LRP5	O75197-1.2	H1243Y	Neutral	0.002
LRP5	O75197-1.2	L1244A	Neutral	0.066
LRP5	O75197-1.2	L1244C	Neutral	0.117
LRP5	O75197-1.2	L1244D	Neutral	0.44
LRP5	O75197-1.2	L1244E	Neutral	0.23
LRP5	O75197-1.2	L1244F	Neutral	0.074
LRP5	O75197-1.2	L1244G	Pathogenic	0.593
LRP5	O75197-1.2	L1244H	Neutral	0.376
LRP5	O75197-1.2	L1244I	Neutral	0.009
LRP5	O75197-1.2	L1244K	Neutral	0.067
LRP5	O75197-1.2	L1244M	Neutral	0.006
LRP5	O75197-1.2	L1244N	Neutral	0.232
LRP5	O75197-1.2	L1244P	Neutral	0.494
LRP5	O75197-1.2	L1244Q	Neutral	0.126
LRP5	O75197-1.2	L1244R	Neutral	0.065
LRP5	O75197-1.2	L1244S	Neutral	0.137
LRP5	O75197-1.2	L1244T	Neutral	0.065
LRP5	O75197-1.2	L1244V	Neutral	0.018
LRP5	O75197-1.2	L1244W	Neutral	0.319
LRP5	O75197-1.2	L1244Y	Neutral	0.119
LRP5	O75197-1.2	V1245A	Neutral	0.052
LRP5	O75197-1.2	V1245C	Neutral	0.238
LRP5	O75197-1.2	V1245D	Neutral	0.378
LRP5	O75197-1.2	V1245E	Neutral	0.186
LRP5	O75197-1.2	V1245F	Neutral	0.185
LRP5	O75197-1.2	V1245G	Pathogenic	0.53
LRP5	O75197-1.2	V1245H	Pathogenic	0.576
LRP5	O75197-1.2	V1245I	Neutral	0.003
LRP5	O75197-1.2	V1245K	Neutral	0.138
LRP5	O75197-1.2	V1245L	Neutral	0.026
LRP5	O75197-1.2	V1245M	Neutral	0.039
LRP5	O75197-1.2	V1245N	Neutral	0.416
LRP5	O75197-1.2	V1245P	Neutral	0.43
LRP5	O75197-1.2	V1245Q	Neutral	0.247
LRP5	O75197-1.2	V1245R	Neutral	0.319
LRP5	O75197-1.2	V1245S	Neutral	0.272
LRP5	O75197-1.2	V1245T	Neutral	0.051
LRP5	O75197-1.2	V1245W	Pathogenic	0.57
LRP5	O75197-1.2	V1245Y	Neutral	0.229
LRP5	O75197-1.2	L1246A	Neutral	0.057
LRP5	O75197-1.2	L1246C	Neutral	0.103
LRP5	O75197-1.2	L1246D	Neutral	0.405
LRP5	O75197-1.2	L1246E	Neutral	0.206
LRP5	O75197-1.2	L1246F	Neutral	0.065
LRP5	O75197-1.2	L1246G	Pathogenic	0.558
LRP5	O75197-1.2	L1246H	Neutral	0.344
LRP5	O75197-1.2	L1246I	Neutral	0.007
LRP5	O75197-1.2	L1246K	Neutral	0.059
LRP5	O75197-1.2	L1246M	Neutral	0.005
LRP5	O75197-1.2	L1246N	Neutral	0.208
LRP5	O75197-1.2	L1246P	Neutral	0.458
LRP5	O75197-1.2	L1246Q	Neutral	0.111
LRP5	O75197-1.2	L1246R	Neutral	0.057
LRP5	O75197-1.2	L1246S	Neutral	0.121
LRP5	O75197-1.2	L1246T	Neutral	0.057
LRP5	O75197-1.2	L1246V	Neutral	0.016
LRP5	O75197-1.2	L1246W	Neutral	0.289
LRP5	O75197-1.2	L1246Y	Neutral	0.104
LRP5	O75197-1.2	L1247A	Neutral	0.006
LRP5	O75197-1.2	L1247C	Neutral	0.011
LRP5	O75197-1.2	L1247D	Neutral	0.064
LRP5	O75197-1.2	L1247E	Neutral	0.025
LRP5	O75197-1.2	L1247F	Neutral	0.007
LRP5	O75197-1.2	L1247G	Neutral	0.113
LRP5	O75197-1.2	L1247H	Neutral	0.05
LRP5	O75197-1.2	L1247I	Neutral	0.001
LRP5	O75197-1.2	L1247K	Neutral	0.006
LRP5	O75197-1.2	L1247M	Neutral	0.001
LRP5	O75197-1.2	L1247N	Neutral	0.026
LRP5	O75197-1.2	L1247P	Neutral	0.078
LRP5	O75197-1.2	L1247Q	Neutral	0.012
LRP5	O75197-1.2	L1247R	Neutral	0.006
LRP5	O75197-1.2	L1247S	Neutral	0.014
LRP5	O75197-1.2	L1247T	Neutral	0.006
LRP5	O75197-1.2	L1247V	Neutral	0.002
LRP5	O75197-1.2	L1247W	Neutral	0.039
LRP5	O75197-1.2	L1247Y	Neutral	0.012
LRP5	O75197-1.2	Q1248A	Neutral	0.009
LRP5	O75197-1.2	Q1248C	Neutral	0.043
LRP5	O75197-1.2	Q1248D	Neutral	0.003
LRP5	O75197-1.2	Q1248E	Neutral	0.0
LRP5	O75197-1.2	Q1248F	Neutral	0.022
LRP5	O75197-1.2	Q1248G	Neutral	0.032
LRP5	O75197-1.2	Q1248H	Neutral	0.004
LRP5	O75197-1.2	Q1248I	Neutral	0.022
LRP5	O75197-1.2	Q1248K	Neutral	0.001
LRP5	O75197-1.2	Q1248L	Neutral	0.008
LRP5	O75197-1.2	Q1248M	Neutral	0.001
LRP5	O75197-1.2	Q1248N	Neutral	0.003
LRP5	O75197-1.2	Q1248P	Neutral	0.006
LRP5	O75197-1.2	Q1248R	Neutral	0.001
LRP5	O75197-1.2	Q1248S	Neutral	0.004
LRP5	O75197-1.2	Q1248T	Neutral	0.009
LRP5	O75197-1.2	Q1248V	Neutral	0.012
LRP5	O75197-1.2	Q1248W	Neutral	0.005
LRP5	O75197-1.2	Q1248Y	Neutral	0.005
LRP5	O75197-1.2	N1249A	Neutral	0.017
LRP5	O75197-1.2	N1249C	Neutral	0.029
LRP5	O75197-1.2	N1249D	Neutral	0.001
LRP5	O75197-1.2	N1249E	Neutral	0.004
LRP5	O75197-1.2	N1249F	Neutral	0.014
LRP5	O75197-1.2	N1249G	Neutral	0.002
LRP5	O75197-1.2	N1249H	Neutral	0.001
LRP5	O75197-1.2	N1249I	Neutral	0.014
LRP5	O75197-1.2	N1249K	Neutral	0.003
LRP5	O75197-1.2	N1249L	Neutral	0.015
LRP5	O75197-1.2	N1249M	Neutral	0.008
LRP5	O75197-1.2	N1249P	Neutral	0.012
LRP5	O75197-1.2	N1249Q	Neutral	0.003
LRP5	O75197-1.2	N1249R	Neutral	0.003
LRP5	O75197-1.2	N1249S	Neutral	0.001
LRP5	O75197-1.2	N1249T	Neutral	0.002
LRP5	O75197-1.2	N1249V	Neutral	0.024
LRP5	O75197-1.2	N1249W	Neutral	0.026
LRP5	O75197-1.2	N1249Y	Neutral	0.009
LRP5	O75197-1.2	L1250A	Neutral	0.0
LRP5	O75197-1.2	L1250C	Neutral	0.001
LRP5	O75197-1.2	L1250D	Neutral	0.005
LRP5	O75197-1.2	L1250E	Neutral	0.002
LRP5	O75197-1.2	L1250F	Neutral	0.001
LRP5	O75197-1.2	L1250G	Neutral	0.01
LRP5	O75197-1.2	L1250H	Neutral	0.004
LRP5	O75197-1.2	L1250I	Neutral	0.0
LRP5	O75197-1.2	L1250K	Neutral	0.0
LRP5	O75197-1.2	L1250M	Neutral	0.0
LRP5	O75197-1.2	L1250N	Neutral	0.002
LRP5	O75197-1.2	L1250P	Neutral	0.006
LRP5	O75197-1.2	L1250Q	Neutral	0.001
LRP5	O75197-1.2	L1250R	Neutral	0.0
LRP5	O75197-1.2	L1250S	Neutral	0.001
LRP5	O75197-1.2	L1250T	Neutral	0.0
LRP5	O75197-1.2	L1250V	Neutral	0.0
LRP5	O75197-1.2	L1250W	Neutral	0.003
LRP5	O75197-1.2	L1250Y	Neutral	0.001
LRP5	O75197-1.2	L1251A	Neutral	0.005
LRP5	O75197-1.2	L1251C	Neutral	0.008
LRP5	O75197-1.2	L1251D	Neutral	0.048
LRP5	O75197-1.2	L1251E	Neutral	0.019
LRP5	O75197-1.2	L1251F	Neutral	0.005
LRP5	O75197-1.2	L1251G	Neutral	0.086
LRP5	O75197-1.2	L1251H	Neutral	0.037
LRP5	O75197-1.2	L1251I	Neutral	0.001
LRP5	O75197-1.2	L1251K	Neutral	0.005
LRP5	O75197-1.2	L1251M	Neutral	0.0
LRP5	O75197-1.2	L1251N	Neutral	0.019
LRP5	O75197-1.2	L1251P	Neutral	0.059
LRP5	O75197-1.2	L1251Q	Neutral	0.009
LRP5	O75197-1.2	L1251R	Neutral	0.004
LRP5	O75197-1.2	L1251S	Neutral	0.01
LRP5	O75197-1.2	L1251T	Neutral	0.004
LRP5	O75197-1.2	L1251V	Neutral	0.001
LRP5	O75197-1.2	L1251W	Neutral	0.029
LRP5	O75197-1.2	L1251Y	Neutral	0.009
LRP5	O75197-1.2	T1252A	Neutral	0.0
LRP5	O75197-1.2	T1252C	Neutral	0.0
LRP5	O75197-1.2	T1252D	Neutral	0.0
LRP5	O75197-1.2	T1252E	Neutral	0.0
LRP5	O75197-1.2	T1252F	Neutral	0.001
LRP5	O75197-1.2	T1252G	Neutral	0.002
LRP5	O75197-1.2	T1252H	Neutral	0.002
LRP5	O75197-1.2	T1252I	Neutral	0.0
LRP5	O75197-1.2	T1252K	Neutral	0.0
LRP5	O75197-1.2	T1252L	Neutral	0.0
LRP5	O75197-1.2	T1252M	Neutral	0.0
LRP5	O75197-1.2	T1252N	Neutral	0.0
LRP5	O75197-1.2	T1252P	Neutral	0.0
LRP5	O75197-1.2	T1252Q	Neutral	0.0
LRP5	O75197-1.2	T1252R	Neutral	0.0
LRP5	O75197-1.2	T1252S	Neutral	0.0
LRP5	O75197-1.2	T1252V	Neutral	0.0
LRP5	O75197-1.2	T1252W	Neutral	0.0
LRP5	O75197-1.2	T1252Y	Neutral	0.001
LRP5	O75197-1.2	C1253A	Pathogenic	0.993
LRP5	O75197-1.2	C1253D	Pathogenic	0.999
LRP5	O75197-1.2	C1253E	Pathogenic	1.0
LRP5	O75197-1.2	C1253F	Pathogenic	0.999
LRP5	O75197-1.2	C1253G	Pathogenic	1.0
LRP5	O75197-1.2	C1253H	Pathogenic	1.0
LRP5	O75197-1.2	C1253I	Pathogenic	0.997
LRP5	O75197-1.2	C1253K	Pathogenic	0.999
LRP5	O75197-1.2	C1253L	Pathogenic	0.998
LRP5	O75197-1.2	C1253M	Pathogenic	0.998
LRP5	O75197-1.2	C1253N	Pathogenic	0.999
LRP5	O75197-1.2	C1253P	Pathogenic	1.0
LRP5	O75197-1.2	C1253Q	Pathogenic	1.0
LRP5	O75197-1.2	C1253R	Pathogenic	0.999
LRP5	O75197-1.2	C1253S	Pathogenic	0.997
LRP5	O75197-1.2	C1253T	Pathogenic	0.998
LRP5	O75197-1.2	C1253V	Pathogenic	0.998
LRP5	O75197-1.2	C1253W	Pathogenic	0.999
LRP5	O75197-1.2	C1253Y	Pathogenic	1.0
LRP5	O75197-1.2	G1254A	Neutral	0.008
LRP5	O75197-1.2	G1254C	Neutral	0.103
LRP5	O75197-1.2	G1254D	Neutral	0.015
LRP5	O75197-1.2	G1254E	Neutral	0.047
LRP5	O75197-1.2	G1254F	Neutral	0.049
LRP5	O75197-1.2	G1254H	Neutral	0.071
LRP5	O75197-1.2	G1254I	Neutral	0.136
LRP5	O75197-1.2	G1254K	Neutral	0.033
LRP5	O75197-1.2	G1254L	Neutral	0.147
LRP5	O75197-1.2	G1254M	Neutral	0.079
LRP5	O75197-1.2	G1254N	Neutral	0.006
LRP5	O75197-1.2	G1254P	Neutral	0.045
LRP5	O75197-1.2	G1254Q	Neutral	0.066
LRP5	O75197-1.2	G1254R	Neutral	0.032
LRP5	O75197-1.2	G1254S	Neutral	0.01
LRP5	O75197-1.2	G1254T	Neutral	0.067
LRP5	O75197-1.2	G1254V	Neutral	0.083
LRP5	O75197-1.2	G1254W	Neutral	0.011
LRP5	O75197-1.2	G1254Y	Neutral	0.097
LRP5	O75197-1.2	E1255A	Neutral	0.006
LRP5	O75197-1.2	E1255C	Neutral	0.088
LRP5	O75197-1.2	E1255D	Neutral	0.0
LRP5	O75197-1.2	E1255F	Neutral	0.015
LRP5	O75197-1.2	E1255G	Neutral	0.023
LRP5	O75197-1.2	E1255H	Neutral	0.002
LRP5	O75197-1.2	E1255I	Neutral	0.015
LRP5	O75197-1.2	E1255K	Neutral	0.001
LRP5	O75197-1.2	E1255L	Neutral	0.017
LRP5	O75197-1.2	E1255M	Neutral	0.008
LRP5	O75197-1.2	E1255N	Neutral	0.005
LRP5	O75197-1.2	E1255P	Neutral	0.004
LRP5	O75197-1.2	E1255Q	Neutral	0.0
LRP5	O75197-1.2	E1255R	Neutral	0.003
LRP5	O75197-1.2	E1255S	Neutral	0.003
LRP5	O75197-1.2	E1255T	Neutral	0.007
LRP5	O75197-1.2	E1255V	Neutral	0.009
LRP5	O75197-1.2	E1255W	Neutral	0.01
LRP5	O75197-1.2	E1255Y	Neutral	0.01
LRP5	O75197-1.2	P1256A	Neutral	0.042
LRP5	O75197-1.2	P1256C	Neutral	0.325
LRP5	O75197-1.2	P1256D	Neutral	0.017
LRP5	O75197-1.2	P1256E	Neutral	0.019
LRP5	O75197-1.2	P1256F	Neutral	0.4
LRP5	O75197-1.2	P1256G	Neutral	0.09
LRP5	O75197-1.2	P1256H	Neutral	0.102
LRP5	O75197-1.2	P1256I	Neutral	0.18
LRP5	O75197-1.2	P1256K	Neutral	0.013
LRP5	O75197-1.2	P1256L	Neutral	0.194
LRP5	O75197-1.2	P1256M	Neutral	0.108
LRP5	O75197-1.2	P1256N	Neutral	0.058
LRP5	O75197-1.2	P1256Q	Neutral	0.027
LRP5	O75197-1.2	P1256R	Neutral	0.038
LRP5	O75197-1.2	P1256S	Neutral	0.032
LRP5	O75197-1.2	P1256T	Neutral	0.042
LRP5	O75197-1.2	P1256V	Neutral	0.112
LRP5	O75197-1.2	P1256W	Neutral	0.297
LRP5	O75197-1.2	P1256Y	Neutral	0.313
LRP5	O75197-1.2	P1257A	Neutral	0.112
LRP5	O75197-1.2	P1257C	Pathogenic	0.579
LRP5	O75197-1.2	P1257D	Neutral	0.048
LRP5	O75197-1.2	P1257E	Neutral	0.052
LRP5	O75197-1.2	P1257F	Pathogenic	0.655
LRP5	O75197-1.2	P1257G	Neutral	0.22
LRP5	O75197-1.2	P1257H	Neutral	0.246
LRP5	O75197-1.2	P1257I	Neutral	0.386
LRP5	O75197-1.2	P1257K	Neutral	0.037
LRP5	O75197-1.2	P1257L	Neutral	0.408
LRP5	O75197-1.2	P1257M	Neutral	0.256
LRP5	O75197-1.2	P1257N	Neutral	0.149
LRP5	O75197-1.2	P1257Q	Neutral	0.073
LRP5	O75197-1.2	P1257R	Neutral	0.101
LRP5	O75197-1.2	P1257S	Neutral	0.086
LRP5	O75197-1.2	P1257T	Neutral	0.111
LRP5	O75197-1.2	P1257V	Neutral	0.264
LRP5	O75197-1.2	P1257W	Pathogenic	0.546
LRP5	O75197-1.2	P1257Y	Pathogenic	0.565
LRP5	O75197-1.2	T1258A	Neutral	0.014
LRP5	O75197-1.2	T1258C	Neutral	0.023
LRP5	O75197-1.2	T1258D	Neutral	0.018
LRP5	O75197-1.2	T1258E	Neutral	0.02
LRP5	O75197-1.2	T1258F	Neutral	0.032
LRP5	O75197-1.2	T1258G	Neutral	0.094
LRP5	O75197-1.2	T1258H	Neutral	0.107
LRP5	O75197-1.2	T1258I	Neutral	0.011
LRP5	O75197-1.2	T1258K	Neutral	0.014
LRP5	O75197-1.2	T1258L	Neutral	0.012
LRP5	O75197-1.2	T1258M	Neutral	0.018
LRP5	O75197-1.2	T1258N	Neutral	0.007
LRP5	O75197-1.2	T1258P	Neutral	0.029
LRP5	O75197-1.2	T1258Q	Neutral	0.028
LRP5	O75197-1.2	T1258R	Neutral	0.013
LRP5	O75197-1.2	T1258S	Neutral	0.004
LRP5	O75197-1.2	T1258V	Neutral	0.006
LRP5	O75197-1.2	T1258W	Neutral	0.021
LRP5	O75197-1.2	T1258Y	Neutral	0.065
LRP5	O75197-1.2	C1259A	Pathogenic	0.985
LRP5	O75197-1.2	C1259D	Pathogenic	0.999
LRP5	O75197-1.2	C1259E	Pathogenic	1.0
LRP5	O75197-1.2	C1259F	Pathogenic	0.998
LRP5	O75197-1.2	C1259G	Pathogenic	0.999
LRP5	O75197-1.2	C1259H	Pathogenic	0.999
LRP5	O75197-1.2	C1259I	Pathogenic	0.994
LRP5	O75197-1.2	C1259K	Pathogenic	0.998
LRP5	O75197-1.2	C1259L	Pathogenic	0.995
LRP5	O75197-1.2	C1259M	Pathogenic	0.997
LRP5	O75197-1.2	C1259N	Pathogenic	0.999
LRP5	O75197-1.2	C1259P	Pathogenic	1.0
LRP5	O75197-1.2	C1259Q	Pathogenic	0.999
LRP5	O75197-1.2	C1259R	Pathogenic	0.998
LRP5	O75197-1.2	C1259S	Pathogenic	0.994
LRP5	O75197-1.2	C1259T	Pathogenic	0.995
LRP5	O75197-1.2	C1259V	Pathogenic	0.997
LRP5	O75197-1.2	C1259W	Pathogenic	0.997
LRP5	O75197-1.2	C1259Y	Pathogenic	0.999
LRP5	O75197-1.2	S1260A	Neutral	0.001
LRP5	O75197-1.2	S1260C	Neutral	0.005
LRP5	O75197-1.2	S1260D	Neutral	0.002
LRP5	O75197-1.2	S1260E	Neutral	0.002
LRP5	O75197-1.2	S1260F	Neutral	0.007
LRP5	O75197-1.2	S1260G	Neutral	0.004
LRP5	O75197-1.2	S1260H	Neutral	0.01
LRP5	O75197-1.2	S1260I	Neutral	0.007
LRP5	O75197-1.2	S1260K	Neutral	0.002
LRP5	O75197-1.2	S1260L	Neutral	0.007
LRP5	O75197-1.2	S1260M	Neutral	0.004
LRP5	O75197-1.2	S1260N	Neutral	0.001
LRP5	O75197-1.2	S1260P	Neutral	0.006
LRP5	O75197-1.2	S1260Q	Neutral	0.003
LRP5	O75197-1.2	S1260R	Neutral	0.005
LRP5	O75197-1.2	S1260T	Neutral	0.001
LRP5	O75197-1.2	S1260V	Neutral	0.012
LRP5	O75197-1.2	S1260W	Neutral	0.013
LRP5	O75197-1.2	S1260Y	Neutral	0.014
LRP5	O75197-1.2	P1261A	Neutral	0.007
LRP5	O75197-1.2	P1261C	Neutral	0.068
LRP5	O75197-1.2	P1261D	Neutral	0.003
LRP5	O75197-1.2	P1261E	Neutral	0.003
LRP5	O75197-1.2	P1261F	Neutral	0.091
LRP5	O75197-1.2	P1261G	Neutral	0.015
LRP5	O75197-1.2	P1261H	Neutral	0.017
LRP5	O75197-1.2	P1261I	Neutral	0.032
LRP5	O75197-1.2	P1261K	Neutral	0.002
LRP5	O75197-1.2	P1261L	Neutral	0.035
LRP5	O75197-1.2	P1261M	Neutral	0.018
LRP5	O75197-1.2	P1261N	Neutral	0.009
LRP5	O75197-1.2	P1261Q	Neutral	0.004
LRP5	O75197-1.2	P1261R	Neutral	0.006
LRP5	O75197-1.2	P1261S	Neutral	0.005
LRP5	O75197-1.2	P1261T	Neutral	0.007
LRP5	O75197-1.2	P1261V	Neutral	0.019
LRP5	O75197-1.2	P1261W	Neutral	0.06
LRP5	O75197-1.2	P1261Y	Neutral	0.064
LRP5	O75197-1.2	D1262A	Neutral	0.001
LRP5	O75197-1.2	D1262C	Neutral	0.002
LRP5	O75197-1.2	D1262E	Neutral	0.0
LRP5	O75197-1.2	D1262F	Neutral	0.001
LRP5	O75197-1.2	D1262G	Neutral	0.0
LRP5	O75197-1.2	D1262H	Neutral	0.0
LRP5	O75197-1.2	D1262I	Neutral	0.001
LRP5	O75197-1.2	D1262K	Neutral	0.001
LRP5	O75197-1.2	D1262L	Neutral	0.002
LRP5	O75197-1.2	D1262M	Neutral	0.001
LRP5	O75197-1.2	D1262N	Neutral	0.0
LRP5	O75197-1.2	D1262P	Neutral	0.0
LRP5	O75197-1.2	D1262Q	Neutral	0.0
LRP5	O75197-1.2	D1262R	Neutral	0.002
LRP5	O75197-1.2	D1262S	Neutral	0.0
LRP5	O75197-1.2	D1262T	Neutral	0.0
LRP5	O75197-1.2	D1262V	Neutral	0.001
LRP5	O75197-1.2	D1262W	Neutral	0.001
LRP5	O75197-1.2	D1262Y	Neutral	0.001
LRP5	O75197-1.2	Q1263A	Neutral	0.025
LRP5	O75197-1.2	Q1263C	Neutral	0.117
LRP5	O75197-1.2	Q1263D	Neutral	0.008
LRP5	O75197-1.2	Q1263E	Neutral	0.001
LRP5	O75197-1.2	Q1263F	Neutral	0.061
LRP5	O75197-1.2	Q1263G	Neutral	0.09
LRP5	O75197-1.2	Q1263H	Neutral	0.01
LRP5	O75197-1.2	Q1263I	Neutral	0.061
LRP5	O75197-1.2	Q1263K	Neutral	0.002
LRP5	O75197-1.2	Q1263L	Neutral	0.023
LRP5	O75197-1.2	Q1263M	Neutral	0.004
LRP5	O75197-1.2	Q1263N	Neutral	0.01
LRP5	O75197-1.2	Q1263P	Neutral	0.018
LRP5	O75197-1.2	Q1263R	Neutral	0.002
LRP5	O75197-1.2	Q1263S	Neutral	0.011
LRP5	O75197-1.2	Q1263T	Neutral	0.027
LRP5	O75197-1.2	Q1263V	Neutral	0.035
LRP5	O75197-1.2	Q1263W	Neutral	0.013
LRP5	O75197-1.2	Q1263Y	Neutral	0.014
LRP5	O75197-1.2	F1264A	Neutral	0.284
LRP5	O75197-1.2	F1264C	Neutral	0.428
LRP5	O75197-1.2	F1264D	Neutral	0.324
LRP5	O75197-1.2	F1264E	Neutral	0.357
LRP5	O75197-1.2	F1264G	Neutral	0.471
LRP5	O75197-1.2	F1264H	Neutral	0.108
LRP5	O75197-1.2	F1264I	Neutral	0.148
LRP5	O75197-1.2	F1264K	Neutral	0.297
LRP5	O75197-1.2	F1264L	Neutral	0.14
LRP5	O75197-1.2	F1264M	Neutral	0.097
LRP5	O75197-1.2	F1264N	Neutral	0.359
LRP5	O75197-1.2	F1264P	Pathogenic	0.846
LRP5	O75197-1.2	F1264Q	Neutral	0.448
LRP5	O75197-1.2	F1264R	Neutral	0.29
LRP5	O75197-1.2	F1264S	Neutral	0.227
LRP5	O75197-1.2	F1264T	Neutral	0.283
LRP5	O75197-1.2	F1264V	Neutral	0.238
LRP5	O75197-1.2	F1264W	Neutral	0.036
LRP5	O75197-1.2	F1264Y	Neutral	0.003
LRP5	O75197-1.2	A1265C	Neutral	0.0
LRP5	O75197-1.2	A1265D	Neutral	0.001
LRP5	O75197-1.2	A1265E	Neutral	0.0
LRP5	O75197-1.2	A1265F	Neutral	0.001
LRP5	O75197-1.2	A1265G	Neutral	0.0
LRP5	O75197-1.2	A1265H	Neutral	0.002
LRP5	O75197-1.2	A1265I	Neutral	0.0
LRP5	O75197-1.2	A1265K	Neutral	0.0
LRP5	O75197-1.2	A1265L	Neutral	0.0
LRP5	O75197-1.2	A1265M	Neutral	0.0
LRP5	O75197-1.2	A1265N	Neutral	0.001
LRP5	O75197-1.2	A1265P	Neutral	0.001
LRP5	O75197-1.2	A1265Q	Neutral	0.001
LRP5	O75197-1.2	A1265R	Neutral	0.0
LRP5	O75197-1.2	A1265S	Neutral	0.0
LRP5	O75197-1.2	A1265T	Neutral	0.0
LRP5	O75197-1.2	A1265V	Neutral	0.0
LRP5	O75197-1.2	A1265W	Neutral	0.001
LRP5	O75197-1.2	A1265Y	Neutral	0.002
LRP5	O75197-1.2	C1266A	Pathogenic	0.984
LRP5	O75197-1.2	C1266D	Pathogenic	0.999
LRP5	O75197-1.2	C1266E	Pathogenic	1.0
LRP5	O75197-1.2	C1266F	Pathogenic	0.998
LRP5	O75197-1.2	C1266G	Pathogenic	0.999
LRP5	O75197-1.2	C1266H	Pathogenic	0.999
LRP5	O75197-1.2	C1266I	Pathogenic	0.994
LRP5	O75197-1.2	C1266K	Pathogenic	0.998
LRP5	O75197-1.2	C1266L	Pathogenic	0.994
LRP5	O75197-1.2	C1266M	Pathogenic	0.996
LRP5	O75197-1.2	C1266N	Pathogenic	0.999
LRP5	O75197-1.2	C1266P	Pathogenic	1.0
LRP5	O75197-1.2	C1266Q	Pathogenic	0.999
LRP5	O75197-1.2	C1266R	Pathogenic	0.998
LRP5	O75197-1.2	C1266S	Pathogenic	0.993
LRP5	O75197-1.2	C1266T	Pathogenic	0.994
LRP5	O75197-1.2	C1266V	Pathogenic	0.996
LRP5	O75197-1.2	C1266W	Pathogenic	0.997
LRP5	O75197-1.2	C1266Y	Pathogenic	0.999
LRP5	O75197-1.2	A1267C	Neutral	0.0
LRP5	O75197-1.2	A1267D	Neutral	0.0
LRP5	O75197-1.2	A1267E	Neutral	0.0
LRP5	O75197-1.2	A1267F	Neutral	0.0
LRP5	O75197-1.2	A1267G	Neutral	0.0
LRP5	O75197-1.2	A1267H	Neutral	0.001
LRP5	O75197-1.2	A1267I	Neutral	0.0
LRP5	O75197-1.2	A1267K	Neutral	0.0
LRP5	O75197-1.2	A1267L	Neutral	0.0
LRP5	O75197-1.2	A1267M	Neutral	0.0
LRP5	O75197-1.2	A1267N	Neutral	0.0
LRP5	O75197-1.2	A1267P	Neutral	0.0
LRP5	O75197-1.2	A1267Q	Neutral	0.0
LRP5	O75197-1.2	A1267R	Neutral	0.0
LRP5	O75197-1.2	A1267S	Neutral	0.0
LRP5	O75197-1.2	A1267T	Neutral	0.0
LRP5	O75197-1.2	A1267V	Neutral	0.0
LRP5	O75197-1.2	A1267W	Neutral	0.001
LRP5	O75197-1.2	A1267Y	Neutral	0.001
LRP5	O75197-1.2	T1268A	Neutral	0.004
LRP5	O75197-1.2	T1268C	Neutral	0.007
LRP5	O75197-1.2	T1268D	Neutral	0.006
LRP5	O75197-1.2	T1268E	Neutral	0.006
LRP5	O75197-1.2	T1268F	Neutral	0.01
LRP5	O75197-1.2	T1268G	Neutral	0.031
LRP5	O75197-1.2	T1268H	Neutral	0.036
LRP5	O75197-1.2	T1268I	Neutral	0.003
LRP5	O75197-1.2	T1268K	Neutral	0.004
LRP5	O75197-1.2	T1268L	Neutral	0.004
LRP5	O75197-1.2	T1268M	Neutral	0.006
LRP5	O75197-1.2	T1268N	Neutral	0.002
LRP5	O75197-1.2	T1268P	Neutral	0.009
LRP5	O75197-1.2	T1268Q	Neutral	0.009
LRP5	O75197-1.2	T1268R	Neutral	0.004
LRP5	O75197-1.2	T1268S	Neutral	0.001
LRP5	O75197-1.2	T1268V	Neutral	0.002
LRP5	O75197-1.2	T1268W	Neutral	0.006
LRP5	O75197-1.2	T1268Y	Neutral	0.021
LRP5	O75197-1.2	G1269A	Neutral	0.014
LRP5	O75197-1.2	G1269C	Neutral	0.17
LRP5	O75197-1.2	G1269D	Neutral	0.026
LRP5	O75197-1.2	G1269E	Neutral	0.081
LRP5	O75197-1.2	G1269F	Neutral	0.084
LRP5	O75197-1.2	G1269H	Neutral	0.121
LRP5	O75197-1.2	G1269I	Neutral	0.22
LRP5	O75197-1.2	G1269K	Neutral	0.058
LRP5	O75197-1.2	G1269L	Neutral	0.236
LRP5	O75197-1.2	G1269M	Neutral	0.134
LRP5	O75197-1.2	G1269N	Neutral	0.01
LRP5	O75197-1.2	G1269P	Neutral	0.078
LRP5	O75197-1.2	G1269Q	Neutral	0.113
LRP5	O75197-1.2	G1269R	Neutral	0.056
LRP5	O75197-1.2	G1269S	Neutral	0.017
LRP5	O75197-1.2	G1269T	Neutral	0.113
LRP5	O75197-1.2	G1269V	Neutral	0.139
LRP5	O75197-1.2	G1269W	Neutral	0.019
LRP5	O75197-1.2	G1269Y	Neutral	0.161
LRP5	O75197-1.2	E1270A	Neutral	0.001
LRP5	O75197-1.2	E1270C	Neutral	0.02
LRP5	O75197-1.2	E1270D	Neutral	0.0
LRP5	O75197-1.2	E1270F	Neutral	0.003
LRP5	O75197-1.2	E1270G	Neutral	0.005
LRP5	O75197-1.2	E1270H	Neutral	0.001
LRP5	O75197-1.2	E1270I	Neutral	0.003
LRP5	O75197-1.2	E1270K	Neutral	0.0
LRP5	O75197-1.2	E1270L	Neutral	0.004
LRP5	O75197-1.2	E1270M	Neutral	0.002
LRP5	O75197-1.2	E1270N	Neutral	0.001
LRP5	O75197-1.2	E1270P	Neutral	0.001
LRP5	O75197-1.2	E1270Q	Neutral	0.0
LRP5	O75197-1.2	E1270R	Neutral	0.001
LRP5	O75197-1.2	E1270S	Neutral	0.001
LRP5	O75197-1.2	E1270T	Neutral	0.001
LRP5	O75197-1.2	E1270V	Neutral	0.002
LRP5	O75197-1.2	E1270W	Neutral	0.002
LRP5	O75197-1.2	E1270Y	Neutral	0.002
LRP5	O75197-1.2	I1271A	Neutral	0.002
LRP5	O75197-1.2	I1271C	Neutral	0.004
LRP5	O75197-1.2	I1271D	Neutral	0.007
LRP5	O75197-1.2	I1271E	Neutral	0.008
LRP5	O75197-1.2	I1271F	Neutral	0.002
LRP5	O75197-1.2	I1271G	Neutral	0.037
LRP5	O75197-1.2	I1271H	Neutral	0.016
LRP5	O75197-1.2	I1271K	Neutral	0.006
LRP5	O75197-1.2	I1271L	Neutral	0.0
LRP5	O75197-1.2	I1271M	Neutral	0.001
LRP5	O75197-1.2	I1271N	Neutral	0.008
LRP5	O75197-1.2	I1271P	Neutral	0.025
LRP5	O75197-1.2	I1271Q	Neutral	0.012
LRP5	O75197-1.2	I1271R	Neutral	0.006
LRP5	O75197-1.2	I1271S	Neutral	0.004
LRP5	O75197-1.2	I1271T	Neutral	0.002
LRP5	O75197-1.2	I1271V	Neutral	0.0
LRP5	O75197-1.2	I1271W	Neutral	0.044
LRP5	O75197-1.2	I1271Y	Neutral	0.004
LRP5	O75197-1.2	D1272A	Neutral	0.028
LRP5	O75197-1.2	D1272C	Neutral	0.047
LRP5	O75197-1.2	D1272E	Neutral	0.001
LRP5	O75197-1.2	D1272F	Neutral	0.022
LRP5	O75197-1.2	D1272G	Neutral	0.012
LRP5	O75197-1.2	D1272H	Neutral	0.011
LRP5	O75197-1.2	D1272I	Neutral	0.022
LRP5	O75197-1.2	D1272K	Neutral	0.019
LRP5	O75197-1.2	D1272L	Neutral	0.07
LRP5	O75197-1.2	D1272M	Neutral	0.036
LRP5	O75197-1.2	D1272N	Neutral	0.002
LRP5	O75197-1.2	D1272P	Neutral	0.007
LRP5	O75197-1.2	D1272Q	Neutral	0.005
LRP5	O75197-1.2	D1272R	Neutral	0.054
LRP5	O75197-1.2	D1272S	Neutral	0.004
LRP5	O75197-1.2	D1272T	Neutral	0.01
LRP5	O75197-1.2	D1272V	Neutral	0.038
LRP5	O75197-1.2	D1272W	Neutral	0.041
LRP5	O75197-1.2	D1272Y	Neutral	0.044
LRP5	O75197-1.2	C1273A	Pathogenic	0.987
LRP5	O75197-1.2	C1273D	Pathogenic	0.999
LRP5	O75197-1.2	C1273E	Pathogenic	1.0
LRP5	O75197-1.2	C1273F	Pathogenic	0.998
LRP5	O75197-1.2	C1273G	Pathogenic	0.999
LRP5	O75197-1.2	C1273H	Pathogenic	0.999
LRP5	O75197-1.2	C1273I	Pathogenic	0.995
LRP5	O75197-1.2	C1273K	Pathogenic	0.998
LRP5	O75197-1.2	C1273L	Pathogenic	0.995
LRP5	O75197-1.2	C1273M	Pathogenic	0.997
LRP5	O75197-1.2	C1273N	Pathogenic	0.999
LRP5	O75197-1.2	C1273P	Pathogenic	1.0
LRP5	O75197-1.2	C1273Q	Pathogenic	0.999
LRP5	O75197-1.2	C1273R	Pathogenic	0.998
LRP5	O75197-1.2	C1273S	Pathogenic	0.994
LRP5	O75197-1.2	C1273T	Pathogenic	0.996
LRP5	O75197-1.2	C1273V	Pathogenic	0.997
LRP5	O75197-1.2	C1273W	Pathogenic	0.997
LRP5	O75197-1.2	C1273Y	Pathogenic	0.999
LRP5	O75197-1.2	I1274A	Neutral	0.077
LRP5	O75197-1.2	I1274C	Neutral	0.136
LRP5	O75197-1.2	I1274D	Neutral	0.235
LRP5	O75197-1.2	I1274E	Neutral	0.262
LRP5	O75197-1.2	I1274F	Neutral	0.1
LRP5	O75197-1.2	I1274G	Pathogenic	0.634
LRP5	O75197-1.2	I1274H	Neutral	0.418
LRP5	O75197-1.2	I1274K	Neutral	0.207
LRP5	O75197-1.2	I1274L	Neutral	0.011
LRP5	O75197-1.2	I1274M	Neutral	0.022
LRP5	O75197-1.2	I1274N	Neutral	0.265
LRP5	O75197-1.2	I1274P	Pathogenic	0.537
LRP5	O75197-1.2	I1274Q	Neutral	0.342
LRP5	O75197-1.2	I1274R	Neutral	0.202
LRP5	O75197-1.2	I1274S	Neutral	0.159
LRP5	O75197-1.2	I1274T	Neutral	0.077
LRP5	O75197-1.2	I1274V	Neutral	0.002
LRP5	O75197-1.2	I1274W	Pathogenic	0.67
LRP5	O75197-1.2	I1274Y	Neutral	0.138
LRP5	O75197-1.2	P1275A	Neutral	0.211
LRP5	O75197-1.2	P1275C	Pathogenic	0.744
LRP5	O75197-1.2	P1275D	Neutral	0.096
LRP5	O75197-1.2	P1275E	Neutral	0.104
LRP5	O75197-1.2	P1275F	Pathogenic	0.801
LRP5	O75197-1.2	P1275G	Neutral	0.375
LRP5	O75197-1.2	P1275H	Neutral	0.408
LRP5	O75197-1.2	P1275I	Pathogenic	0.571
LRP5	O75197-1.2	P1275K	Neutral	0.075
LRP5	O75197-1.2	P1275L	Pathogenic	0.593
LRP5	O75197-1.2	P1275M	Neutral	0.422
LRP5	O75197-1.2	P1275N	Neutral	0.27
LRP5	O75197-1.2	P1275Q	Neutral	0.143
LRP5	O75197-1.2	P1275R	Neutral	0.192
LRP5	O75197-1.2	P1275S	Neutral	0.166
LRP5	O75197-1.2	P1275T	Neutral	0.209
LRP5	O75197-1.2	P1275V	Neutral	0.432
LRP5	O75197-1.2	P1275W	Pathogenic	0.718
LRP5	O75197-1.2	P1275Y	Pathogenic	0.733
LRP5	O75197-1.2	G1276A	Neutral	0.0
LRP5	O75197-1.2	G1276C	Neutral	0.0
LRP5	O75197-1.2	G1276D	Neutral	0.0
LRP5	O75197-1.2	G1276E	Neutral	0.0
LRP5	O75197-1.2	G1276F	Neutral	0.0
LRP5	O75197-1.2	G1276H	Neutral	0.0
LRP5	O75197-1.2	G1276I	Neutral	0.0
LRP5	O75197-1.2	G1276K	Neutral	0.0
LRP5	O75197-1.2	G1276L	Neutral	0.0
LRP5	O75197-1.2	G1276M	Neutral	0.0
LRP5	O75197-1.2	G1276N	Neutral	0.0
LRP5	O75197-1.2	G1276P	Neutral	0.0
LRP5	O75197-1.2	G1276Q	Neutral	0.0
LRP5	O75197-1.2	G1276R	Neutral	0.0
LRP5	O75197-1.2	G1276S	Neutral	0.0
LRP5	O75197-1.2	G1276T	Neutral	0.0
LRP5	O75197-1.2	G1276V	Neutral	0.0
LRP5	O75197-1.2	G1276W	Neutral	0.0
LRP5	O75197-1.2	G1276Y	Neutral	0.0
LRP5	O75197-1.2	A1277C	Neutral	0.002
LRP5	O75197-1.2	A1277D	Neutral	0.011
LRP5	O75197-1.2	A1277E	Neutral	0.004
LRP5	O75197-1.2	A1277F	Neutral	0.007
LRP5	O75197-1.2	A1277G	Neutral	0.002
LRP5	O75197-1.2	A1277H	Neutral	0.022
LRP5	O75197-1.2	A1277I	Neutral	0.002
LRP5	O75197-1.2	A1277K	Neutral	0.003
LRP5	O75197-1.2	A1277L	Neutral	0.003
LRP5	O75197-1.2	A1277M	Neutral	0.004
LRP5	O75197-1.2	A1277N	Neutral	0.012
LRP5	O75197-1.2	A1277P	Neutral	0.006
LRP5	O75197-1.2	A1277Q	Neutral	0.006
LRP5	O75197-1.2	A1277R	Neutral	0.003
LRP5	O75197-1.2	A1277S	Neutral	0.001
LRP5	O75197-1.2	A1277T	Neutral	0.003
LRP5	O75197-1.2	A1277V	Neutral	0.001
LRP5	O75197-1.2	A1277W	Neutral	0.013
LRP5	O75197-1.2	A1277Y	Neutral	0.014
LRP5	O75197-1.2	W1278A	Pathogenic	0.657
LRP5	O75197-1.2	W1278C	Pathogenic	0.542
LRP5	O75197-1.2	W1278D	Pathogenic	0.698
LRP5	O75197-1.2	W1278E	Neutral	0.468
LRP5	O75197-1.2	W1278F	Neutral	0.086
LRP5	O75197-1.2	W1278G	Neutral	0.317
LRP5	O75197-1.2	W1278H	Neutral	0.368
LRP5	O75197-1.2	W1278I	Pathogenic	0.889
LRP5	O75197-1.2	W1278K	Neutral	0.401
LRP5	O75197-1.2	W1278L	Pathogenic	0.705
LRP5	O75197-1.2	W1278M	Neutral	0.341
LRP5	O75197-1.2	W1278N	Pathogenic	0.73
LRP5	O75197-1.2	W1278P	Pathogenic	0.897
LRP5	O75197-1.2	W1278Q	Neutral	0.297
LRP5	O75197-1.2	W1278R	Neutral	0.403
LRP5	O75197-1.2	W1278S	Pathogenic	0.587
LRP5	O75197-1.2	W1278T	Neutral	0.385
LRP5	O75197-1.2	W1278V	Pathogenic	0.821
LRP5	O75197-1.2	W1278Y	Neutral	0.015
LRP5	O75197-1.2	R1279A	Neutral	0.017
LRP5	O75197-1.2	R1279C	Neutral	0.083
LRP5	O75197-1.2	R1279D	Neutral	0.125
LRP5	O75197-1.2	R1279E	Neutral	0.014
LRP5	O75197-1.2	R1279F	Neutral	0.045
LRP5	O75197-1.2	R1279G	Neutral	0.063
LRP5	O75197-1.2	R1279H	Neutral	0.007
LRP5	O75197-1.2	R1279I	Neutral	0.044
LRP5	O75197-1.2	R1279K	Neutral	0.002
LRP5	O75197-1.2	R1279L	Neutral	0.016
LRP5	O75197-1.2	R1279M	Neutral	0.008
LRP5	O75197-1.2	R1279N	Neutral	0.013
LRP5	O75197-1.2	R1279P	Neutral	0.036
LRP5	O75197-1.2	R1279Q	Neutral	0.003
LRP5	O75197-1.2	R1279S	Neutral	0.023
LRP5	O75197-1.2	R1279T	Neutral	0.019
LRP5	O75197-1.2	R1279V	Neutral	0.07
LRP5	O75197-1.2	R1279W	Neutral	0.03
LRP5	O75197-1.2	R1279Y	Neutral	0.032
LRP5	O75197-1.2	C1280A	Pathogenic	0.986
LRP5	O75197-1.2	C1280D	Pathogenic	0.999
LRP5	O75197-1.2	C1280E	Pathogenic	1.0
LRP5	O75197-1.2	C1280F	Pathogenic	0.998
LRP5	O75197-1.2	C1280G	Pathogenic	0.999
LRP5	O75197-1.2	C1280H	Pathogenic	0.999
LRP5	O75197-1.2	C1280I	Pathogenic	0.995
LRP5	O75197-1.2	C1280K	Pathogenic	0.998
LRP5	O75197-1.2	C1280L	Pathogenic	0.995
LRP5	O75197-1.2	C1280M	Pathogenic	0.997
LRP5	O75197-1.2	C1280N	Pathogenic	0.999
LRP5	O75197-1.2	C1280P	Pathogenic	1.0
LRP5	O75197-1.2	C1280Q	Pathogenic	0.999
LRP5	O75197-1.2	C1280R	Pathogenic	0.998
LRP5	O75197-1.2	C1280S	Pathogenic	0.994
LRP5	O75197-1.2	C1280T	Pathogenic	0.995
LRP5	O75197-1.2	C1280V	Pathogenic	0.997
LRP5	O75197-1.2	C1280W	Pathogenic	0.997
LRP5	O75197-1.2	C1280Y	Pathogenic	0.999
LRP5	O75197-1.2	D1281A	Neutral	0.203
LRP5	O75197-1.2	D1281C	Neutral	0.304
LRP5	O75197-1.2	D1281E	Neutral	0.007
LRP5	O75197-1.2	D1281F	Neutral	0.167
LRP5	O75197-1.2	D1281G	Neutral	0.097
LRP5	O75197-1.2	D1281H	Neutral	0.089
LRP5	O75197-1.2	D1281I	Neutral	0.167
LRP5	O75197-1.2	D1281K	Neutral	0.149
LRP5	O75197-1.2	D1281L	Neutral	0.401
LRP5	O75197-1.2	D1281M	Neutral	0.251
LRP5	O75197-1.2	D1281N	Neutral	0.021
LRP5	O75197-1.2	D1281P	Neutral	0.057
LRP5	O75197-1.2	D1281Q	Neutral	0.042
LRP5	O75197-1.2	D1281R	Neutral	0.34
LRP5	O75197-1.2	D1281S	Neutral	0.036
LRP5	O75197-1.2	D1281T	Neutral	0.083
LRP5	O75197-1.2	D1281V	Neutral	0.259
LRP5	O75197-1.2	D1281W	Neutral	0.278
LRP5	O75197-1.2	D1281Y	Neutral	0.293
LRP5	O75197-1.2	G1282A	Neutral	0.026
LRP5	O75197-1.2	G1282C	Neutral	0.287
LRP5	O75197-1.2	G1282D	Neutral	0.049
LRP5	O75197-1.2	G1282E	Neutral	0.148
LRP5	O75197-1.2	G1282F	Neutral	0.153
LRP5	O75197-1.2	G1282H	Neutral	0.212
LRP5	O75197-1.2	G1282I	Neutral	0.356
LRP5	O75197-1.2	G1282K	Neutral	0.108
LRP5	O75197-1.2	G1282L	Neutral	0.377
LRP5	O75197-1.2	G1282M	Neutral	0.232
LRP5	O75197-1.2	G1282N	Neutral	0.019
LRP5	O75197-1.2	G1282P	Neutral	0.142
LRP5	O75197-1.2	G1282Q	Neutral	0.2
LRP5	O75197-1.2	G1282R	Neutral	0.105
LRP5	O75197-1.2	G1282S	Neutral	0.033
LRP5	O75197-1.2	G1282T	Neutral	0.2
LRP5	O75197-1.2	G1282V	Neutral	0.24
LRP5	O75197-1.2	G1282W	Neutral	0.036
LRP5	O75197-1.2	G1282Y	Neutral	0.273
LRP5	O75197-1.2	F1283A	Neutral	0.004
LRP5	O75197-1.2	F1283C	Neutral	0.008
LRP5	O75197-1.2	F1283D	Neutral	0.005
LRP5	O75197-1.2	F1283E	Neutral	0.006
LRP5	O75197-1.2	F1283G	Neutral	0.009
LRP5	O75197-1.2	F1283H	Neutral	0.001
LRP5	O75197-1.2	F1283I	Neutral	0.002
LRP5	O75197-1.2	F1283K	Neutral	0.004
LRP5	O75197-1.2	F1283L	Neutral	0.002
LRP5	O75197-1.2	F1283M	Neutral	0.001
LRP5	O75197-1.2	F1283N	Neutral	0.006
LRP5	O75197-1.2	F1283P	Neutral	0.054
LRP5	O75197-1.2	F1283Q	Neutral	0.008
LRP5	O75197-1.2	F1283R	Neutral	0.004
LRP5	O75197-1.2	F1283S	Neutral	0.003
LRP5	O75197-1.2	F1283T	Neutral	0.004
LRP5	O75197-1.2	F1283V	Neutral	0.003
LRP5	O75197-1.2	F1283W	Neutral	0.0
LRP5	O75197-1.2	F1283Y	Neutral	0.0
LRP5	O75197-1.2	P1284A	Neutral	0.0
LRP5	O75197-1.2	P1284C	Neutral	0.003
LRP5	O75197-1.2	P1284D	Neutral	0.0
LRP5	O75197-1.2	P1284E	Neutral	0.0
LRP5	O75197-1.2	P1284F	Neutral	0.004
LRP5	O75197-1.2	P1284G	Neutral	0.001
LRP5	O75197-1.2	P1284H	Neutral	0.001
LRP5	O75197-1.2	P1284I	Neutral	0.001
LRP5	O75197-1.2	P1284K	Neutral	0.0
LRP5	O75197-1.2	P1284L	Neutral	0.002
LRP5	O75197-1.2	P1284M	Neutral	0.001
LRP5	O75197-1.2	P1284N	Neutral	0.0
LRP5	O75197-1.2	P1284Q	Neutral	0.0
LRP5	O75197-1.2	P1284R	Neutral	0.0
LRP5	O75197-1.2	P1284S	Neutral	0.0
LRP5	O75197-1.2	P1284T	Neutral	0.0
LRP5	O75197-1.2	P1284V	Neutral	0.001
LRP5	O75197-1.2	P1284W	Neutral	0.003
LRP5	O75197-1.2	P1284Y	Neutral	0.003
LRP5	O75197-1.2	E1285A	Neutral	0.039
LRP5	O75197-1.2	E1285C	Neutral	0.391
LRP5	O75197-1.2	E1285D	Neutral	0.003
LRP5	O75197-1.2	E1285F	Neutral	0.093
LRP5	O75197-1.2	E1285G	Neutral	0.136
LRP5	O75197-1.2	E1285H	Neutral	0.016
LRP5	O75197-1.2	E1285I	Neutral	0.093
LRP5	O75197-1.2	E1285K	Neutral	0.008
LRP5	O75197-1.2	E1285L	Neutral	0.101
LRP5	O75197-1.2	E1285M	Neutral	0.053
LRP5	O75197-1.2	E1285N	Neutral	0.03
LRP5	O75197-1.2	E1285P	Neutral	0.028
LRP5	O75197-1.2	E1285Q	Neutral	0.002
LRP5	O75197-1.2	E1285R	Neutral	0.022
LRP5	O75197-1.2	E1285S	Neutral	0.018
LRP5	O75197-1.2	E1285T	Neutral	0.042
LRP5	O75197-1.2	E1285V	Neutral	0.055
LRP5	O75197-1.2	E1285W	Neutral	0.061
LRP5	O75197-1.2	E1285Y	Neutral	0.065
LRP5	O75197-1.2	C1286A	Pathogenic	0.988
LRP5	O75197-1.2	C1286D	Pathogenic	0.999
LRP5	O75197-1.2	C1286E	Pathogenic	1.0
LRP5	O75197-1.2	C1286F	Pathogenic	0.998
LRP5	O75197-1.2	C1286G	Pathogenic	0.999
LRP5	O75197-1.2	C1286H	Pathogenic	0.999
LRP5	O75197-1.2	C1286I	Pathogenic	0.995
LRP5	O75197-1.2	C1286K	Pathogenic	0.998
LRP5	O75197-1.2	C1286L	Pathogenic	0.996
LRP5	O75197-1.2	C1286M	Pathogenic	0.997
LRP5	O75197-1.2	C1286N	Pathogenic	0.999
LRP5	O75197-1.2	C1286P	Pathogenic	1.0
LRP5	O75197-1.2	C1286Q	Pathogenic	0.999
LRP5	O75197-1.2	C1286R	Pathogenic	0.998
LRP5	O75197-1.2	C1286S	Pathogenic	0.994
LRP5	O75197-1.2	C1286T	Pathogenic	0.996
LRP5	O75197-1.2	C1286V	Pathogenic	0.997
LRP5	O75197-1.2	C1286W	Pathogenic	0.997
LRP5	O75197-1.2	C1286Y	Pathogenic	0.999
LRP5	O75197-1.2	D1287A	Neutral	0.0
LRP5	O75197-1.2	D1287C	Neutral	0.001
LRP5	O75197-1.2	D1287E	Neutral	0.0
LRP5	O75197-1.2	D1287F	Neutral	0.0
LRP5	O75197-1.2	D1287G	Neutral	0.0
LRP5	O75197-1.2	D1287H	Neutral	0.0
LRP5	O75197-1.2	D1287I	Neutral	0.0
LRP5	O75197-1.2	D1287K	Neutral	0.0
LRP5	O75197-1.2	D1287L	Neutral	0.001
LRP5	O75197-1.2	D1287M	Neutral	0.001
LRP5	O75197-1.2	D1287N	Neutral	0.0
LRP5	O75197-1.2	D1287P	Neutral	0.0
LRP5	O75197-1.2	D1287Q	Neutral	0.0
LRP5	O75197-1.2	D1287R	Neutral	0.001
LRP5	O75197-1.2	D1287S	Neutral	0.0
LRP5	O75197-1.2	D1287T	Neutral	0.0
LRP5	O75197-1.2	D1287V	Neutral	0.001
LRP5	O75197-1.2	D1287W	Neutral	0.001
LRP5	O75197-1.2	D1287Y	Neutral	0.001
LRP5	O75197-1.2	D1288A	Neutral	0.19
LRP5	O75197-1.2	D1288C	Neutral	0.287
LRP5	O75197-1.2	D1288E	Neutral	0.006
LRP5	O75197-1.2	D1288F	Neutral	0.156
LRP5	O75197-1.2	D1288G	Neutral	0.09
LRP5	O75197-1.2	D1288H	Neutral	0.083
LRP5	O75197-1.2	D1288I	Neutral	0.156
LRP5	O75197-1.2	D1288K	Neutral	0.139
LRP5	O75197-1.2	D1288L	Neutral	0.382
LRP5	O75197-1.2	D1288M	Neutral	0.236
LRP5	O75197-1.2	D1288N	Neutral	0.019
LRP5	O75197-1.2	D1288P	Neutral	0.053
LRP5	O75197-1.2	D1288Q	Neutral	0.039
LRP5	O75197-1.2	D1288R	Neutral	0.322
LRP5	O75197-1.2	D1288S	Neutral	0.034
LRP5	O75197-1.2	D1288T	Neutral	0.077
LRP5	O75197-1.2	D1288V	Neutral	0.244
LRP5	O75197-1.2	D1288W	Neutral	0.262
LRP5	O75197-1.2	D1288Y	Neutral	0.277
LRP5	O75197-1.2	Q1289A	Neutral	0.0
LRP5	O75197-1.2	Q1289C	Neutral	0.001
LRP5	O75197-1.2	Q1289D	Neutral	0.0
LRP5	O75197-1.2	Q1289E	Neutral	0.0
LRP5	O75197-1.2	Q1289F	Neutral	0.0
LRP5	O75197-1.2	Q1289G	Neutral	0.0
LRP5	O75197-1.2	Q1289H	Neutral	0.0
LRP5	O75197-1.2	Q1289I	Neutral	0.0
LRP5	O75197-1.2	Q1289K	Neutral	0.0
LRP5	O75197-1.2	Q1289L	Neutral	0.0
LRP5	O75197-1.2	Q1289M	Neutral	0.0
LRP5	O75197-1.2	Q1289N	Neutral	0.0
LRP5	O75197-1.2	Q1289P	Neutral	0.0
LRP5	O75197-1.2	Q1289R	Neutral	0.0
LRP5	O75197-1.2	Q1289S	Neutral	0.0
LRP5	O75197-1.2	Q1289T	Neutral	0.0
LRP5	O75197-1.2	Q1289V	Neutral	0.0
LRP5	O75197-1.2	Q1289W	Neutral	0.0
LRP5	O75197-1.2	Q1289Y	Neutral	0.0
LRP5	O75197-1.2	S1290A	Neutral	0.017
LRP5	O75197-1.2	S1290C	Neutral	0.078
LRP5	O75197-1.2	S1290D	Neutral	0.034
LRP5	O75197-1.2	S1290E	Neutral	0.037
LRP5	O75197-1.2	S1290F	Neutral	0.103
LRP5	O75197-1.2	S1290G	Neutral	0.061
LRP5	O75197-1.2	S1290H	Neutral	0.146
LRP5	O75197-1.2	S1290I	Neutral	0.104
LRP5	O75197-1.2	S1290K	Neutral	0.026
LRP5	O75197-1.2	S1290L	Neutral	0.112
LRP5	O75197-1.2	S1290M	Neutral	0.06
LRP5	O75197-1.2	S1290N	Neutral	0.013
LRP5	O75197-1.2	S1290P	Neutral	0.096
LRP5	O75197-1.2	S1290Q	Neutral	0.053
LRP5	O75197-1.2	S1290R	Neutral	0.074
LRP5	O75197-1.2	S1290T	Neutral	0.017
LRP5	O75197-1.2	S1290V	Neutral	0.168
LRP5	O75197-1.2	S1290W	Neutral	0.181
LRP5	O75197-1.2	S1290Y	Neutral	0.193
LRP5	O75197-1.2	D1291A	Neutral	0.19
LRP5	O75197-1.2	D1291C	Neutral	0.287
LRP5	O75197-1.2	D1291E	Neutral	0.006
LRP5	O75197-1.2	D1291F	Neutral	0.156
LRP5	O75197-1.2	D1291G	Neutral	0.09
LRP5	O75197-1.2	D1291H	Neutral	0.083
LRP5	O75197-1.2	D1291I	Neutral	0.156
LRP5	O75197-1.2	D1291K	Neutral	0.139
LRP5	O75197-1.2	D1291L	Neutral	0.382
LRP5	O75197-1.2	D1291M	Neutral	0.236
LRP5	O75197-1.2	D1291N	Neutral	0.019
LRP5	O75197-1.2	D1291P	Neutral	0.053
LRP5	O75197-1.2	D1291Q	Neutral	0.039
LRP5	O75197-1.2	D1291R	Neutral	0.322
LRP5	O75197-1.2	D1291S	Neutral	0.034
LRP5	O75197-1.2	D1291T	Neutral	0.077
LRP5	O75197-1.2	D1291V	Neutral	0.244
LRP5	O75197-1.2	D1291W	Neutral	0.262
LRP5	O75197-1.2	D1291Y	Neutral	0.277
LRP5	O75197-1.2	E1292A	Neutral	0.134
LRP5	O75197-1.2	E1292C	Pathogenic	0.71
LRP5	O75197-1.2	E1292D	Neutral	0.012
LRP5	O75197-1.2	E1292F	Neutral	0.28
LRP5	O75197-1.2	E1292G	Neutral	0.375
LRP5	O75197-1.2	E1292H	Neutral	0.059
LRP5	O75197-1.2	E1292I	Neutral	0.281
LRP5	O75197-1.2	E1292K	Neutral	0.028
LRP5	O75197-1.2	E1292L	Neutral	0.3
LRP5	O75197-1.2	E1292M	Neutral	0.176
LRP5	O75197-1.2	E1292N	Neutral	0.107
LRP5	O75197-1.2	E1292P	Neutral	0.1
LRP5	O75197-1.2	E1292Q	Neutral	0.009
LRP5	O75197-1.2	E1292R	Neutral	0.079
LRP5	O75197-1.2	E1292S	Neutral	0.065
LRP5	O75197-1.2	E1292T	Neutral	0.144
LRP5	O75197-1.2	E1292V	Neutral	0.181
LRP5	O75197-1.2	E1292W	Neutral	0.198
LRP5	O75197-1.2	E1292Y	Neutral	0.21
LRP5	O75197-1.2	E1293A	Neutral	0.0
LRP5	O75197-1.2	E1293C	Neutral	0.001
LRP5	O75197-1.2	E1293D	Neutral	0.0
LRP5	O75197-1.2	E1293F	Neutral	0.0
LRP5	O75197-1.2	E1293G	Neutral	0.0
LRP5	O75197-1.2	E1293H	Neutral	0.0
LRP5	O75197-1.2	E1293I	Neutral	0.0
LRP5	O75197-1.2	E1293K	Neutral	0.0
LRP5	O75197-1.2	E1293L	Neutral	0.0
LRP5	O75197-1.2	E1293M	Neutral	0.0
LRP5	O75197-1.2	E1293N	Neutral	0.0
LRP5	O75197-1.2	E1293P	Neutral	0.0
LRP5	O75197-1.2	E1293Q	Neutral	0.0
LRP5	O75197-1.2	E1293R	Neutral	0.0
LRP5	O75197-1.2	E1293S	Neutral	0.0
LRP5	O75197-1.2	E1293T	Neutral	0.0
LRP5	O75197-1.2	E1293V	Neutral	0.0
LRP5	O75197-1.2	E1293W	Neutral	0.0
LRP5	O75197-1.2	E1293Y	Neutral	0.0
LRP5	O75197-1.2	G1294A	Neutral	0.0
LRP5	O75197-1.2	G1294C	Neutral	0.001
LRP5	O75197-1.2	G1294D	Neutral	0.0
LRP5	O75197-1.2	G1294E	Neutral	0.0
LRP5	O75197-1.2	G1294F	Neutral	0.0
LRP5	O75197-1.2	G1294H	Neutral	0.001
LRP5	O75197-1.2	G1294I	Neutral	0.001
LRP5	O75197-1.2	G1294K	Neutral	0.0
LRP5	O75197-1.2	G1294L	Neutral	0.002
LRP5	O75197-1.2	G1294M	Neutral	0.001
LRP5	O75197-1.2	G1294N	Neutral	0.0
LRP5	O75197-1.2	G1294P	Neutral	0.0
LRP5	O75197-1.2	G1294Q	Neutral	0.001
LRP5	O75197-1.2	G1294R	Neutral	0.0
LRP5	O75197-1.2	G1294S	Neutral	0.0
LRP5	O75197-1.2	G1294T	Neutral	0.001
LRP5	O75197-1.2	G1294V	Neutral	0.001
LRP5	O75197-1.2	G1294W	Neutral	0.0
LRP5	O75197-1.2	G1294Y	Neutral	0.001
LRP5	O75197-1.2	C1295A	Pathogenic	0.985
LRP5	O75197-1.2	C1295D	Pathogenic	0.999
LRP5	O75197-1.2	C1295E	Pathogenic	1.0
LRP5	O75197-1.2	C1295F	Pathogenic	0.998
LRP5	O75197-1.2	C1295G	Pathogenic	0.999
LRP5	O75197-1.2	C1295H	Pathogenic	0.999
LRP5	O75197-1.2	C1295I	Pathogenic	0.994
LRP5	O75197-1.2	C1295K	Pathogenic	0.998
LRP5	O75197-1.2	C1295L	Pathogenic	0.995
LRP5	O75197-1.2	C1295M	Pathogenic	0.996
LRP5	O75197-1.2	C1295N	Pathogenic	0.999
LRP5	O75197-1.2	C1295P	Pathogenic	1.0
LRP5	O75197-1.2	C1295Q	Pathogenic	0.999
LRP5	O75197-1.2	C1295R	Pathogenic	0.998
LRP5	O75197-1.2	C1295S	Pathogenic	0.993
LRP5	O75197-1.2	C1295T	Pathogenic	0.995
LRP5	O75197-1.2	C1295V	Pathogenic	0.997
LRP5	O75197-1.2	C1295W	Pathogenic	0.997
LRP5	O75197-1.2	C1295Y	Pathogenic	0.999
LRP5	O75197-1.2	P1296A	Neutral	0.133
LRP5	O75197-1.2	P1296C	Pathogenic	0.624
LRP5	O75197-1.2	P1296D	Neutral	0.057
LRP5	O75197-1.2	P1296E	Neutral	0.062
LRP5	O75197-1.2	P1296F	Pathogenic	0.697
LRP5	O75197-1.2	P1296G	Neutral	0.255
LRP5	O75197-1.2	P1296H	Neutral	0.283
LRP5	O75197-1.2	P1296I	Neutral	0.432
LRP5	O75197-1.2	P1296K	Neutral	0.044
LRP5	O75197-1.2	P1296L	Neutral	0.454
LRP5	O75197-1.2	P1296M	Neutral	0.294
LRP5	O75197-1.2	P1296N	Neutral	0.175
LRP5	O75197-1.2	P1296Q	Neutral	0.087
LRP5	O75197-1.2	P1296R	Neutral	0.12
LRP5	O75197-1.2	P1296S	Neutral	0.102
LRP5	O75197-1.2	P1296T	Neutral	0.131
LRP5	O75197-1.2	P1296V	Neutral	0.303
LRP5	O75197-1.2	P1296W	Pathogenic	0.593
LRP5	O75197-1.2	P1296Y	Pathogenic	0.611
LRP5	O75197-1.2	V1297A	Neutral	0.0
LRP5	O75197-1.2	V1297C	Neutral	0.001
LRP5	O75197-1.2	V1297D	Neutral	0.003
LRP5	O75197-1.2	V1297E	Neutral	0.001
LRP5	O75197-1.2	V1297F	Neutral	0.001
LRP5	O75197-1.2	V1297G	Neutral	0.005
LRP5	O75197-1.2	V1297H	Neutral	0.006
LRP5	O75197-1.2	V1297I	Neutral	0.0
LRP5	O75197-1.2	V1297K	Neutral	0.001
LRP5	O75197-1.2	V1297L	Neutral	0.0
LRP5	O75197-1.2	V1297M	Neutral	0.0
LRP5	O75197-1.2	V1297N	Neutral	0.003
LRP5	O75197-1.2	V1297P	Neutral	0.003
LRP5	O75197-1.2	V1297Q	Neutral	0.001
LRP5	O75197-1.2	V1297R	Neutral	0.002
LRP5	O75197-1.2	V1297S	Neutral	0.002
LRP5	O75197-1.2	V1297T	Neutral	0.0
LRP5	O75197-1.2	V1297W	Neutral	0.006
LRP5	O75197-1.2	V1297Y	Neutral	0.001
LRP5	O75197-1.2	C1298A	Pathogenic	0.988
LRP5	O75197-1.2	C1298D	Pathogenic	0.999
LRP5	O75197-1.2	C1298E	Pathogenic	1.0
LRP5	O75197-1.2	C1298F	Pathogenic	0.998
LRP5	O75197-1.2	C1298G	Pathogenic	0.999
LRP5	O75197-1.2	C1298H	Pathogenic	0.999
LRP5	O75197-1.2	C1298I	Pathogenic	0.995
LRP5	O75197-1.2	C1298K	Pathogenic	0.998
LRP5	O75197-1.2	C1298L	Pathogenic	0.996
LRP5	O75197-1.2	C1298M	Pathogenic	0.997
LRP5	O75197-1.2	C1298N	Pathogenic	0.999
LRP5	O75197-1.2	C1298P	Pathogenic	1.0
LRP5	O75197-1.2	C1298Q	Pathogenic	0.999
LRP5	O75197-1.2	C1298R	Pathogenic	0.998
LRP5	O75197-1.2	C1298S	Pathogenic	0.994
LRP5	O75197-1.2	C1298T	Pathogenic	0.996
LRP5	O75197-1.2	C1298V	Pathogenic	0.997
LRP5	O75197-1.2	C1298W	Pathogenic	0.997
LRP5	O75197-1.2	C1298Y	Pathogenic	0.999
LRP5	O75197-1.2	S1299A	Neutral	0.002
LRP5	O75197-1.2	S1299C	Neutral	0.008
LRP5	O75197-1.2	S1299D	Neutral	0.003
LRP5	O75197-1.2	S1299E	Neutral	0.004
LRP5	O75197-1.2	S1299F	Neutral	0.01
LRP5	O75197-1.2	S1299G	Neutral	0.006
LRP5	O75197-1.2	S1299H	Neutral	0.015
LRP5	O75197-1.2	S1299I	Neutral	0.01
LRP5	O75197-1.2	S1299K	Neutral	0.002
LRP5	O75197-1.2	S1299L	Neutral	0.011
LRP5	O75197-1.2	S1299M	Neutral	0.006
LRP5	O75197-1.2	S1299N	Neutral	0.001
LRP5	O75197-1.2	S1299P	Neutral	0.01
LRP5	O75197-1.2	S1299Q	Neutral	0.005
LRP5	O75197-1.2	S1299R	Neutral	0.007
LRP5	O75197-1.2	S1299T	Neutral	0.002
LRP5	O75197-1.2	S1299V	Neutral	0.018
LRP5	O75197-1.2	S1299W	Neutral	0.02
LRP5	O75197-1.2	S1299Y	Neutral	0.021
LRP5	O75197-1.2	A1300C	Neutral	0.0
LRP5	O75197-1.2	A1300D	Neutral	0.0
LRP5	O75197-1.2	A1300E	Neutral	0.0
LRP5	O75197-1.2	A1300F	Neutral	0.0
LRP5	O75197-1.2	A1300G	Neutral	0.0
LRP5	O75197-1.2	A1300H	Neutral	0.0
LRP5	O75197-1.2	A1300I	Neutral	0.0
LRP5	O75197-1.2	A1300K	Neutral	0.0
LRP5	O75197-1.2	A1300L	Neutral	0.0
LRP5	O75197-1.2	A1300M	Neutral	0.0
LRP5	O75197-1.2	A1300N	Neutral	0.0
LRP5	O75197-1.2	A1300P	Neutral	0.0
LRP5	O75197-1.2	A1300Q	Neutral	0.0
LRP5	O75197-1.2	A1300R	Neutral	0.0
LRP5	O75197-1.2	A1300S	Neutral	0.0
LRP5	O75197-1.2	A1300T	Neutral	0.0
LRP5	O75197-1.2	A1300V	Neutral	0.0
LRP5	O75197-1.2	A1300W	Neutral	0.0
LRP5	O75197-1.2	A1300Y	Neutral	0.0
LRP5	O75197-1.2	A1301C	Neutral	0.0
LRP5	O75197-1.2	A1301D	Neutral	0.0
LRP5	O75197-1.2	A1301E	Neutral	0.0
LRP5	O75197-1.2	A1301F	Neutral	0.0
LRP5	O75197-1.2	A1301G	Neutral	0.0
LRP5	O75197-1.2	A1301H	Neutral	0.0
LRP5	O75197-1.2	A1301I	Neutral	0.0
LRP5	O75197-1.2	A1301K	Neutral	0.0
LRP5	O75197-1.2	A1301L	Neutral	0.0
LRP5	O75197-1.2	A1301M	Neutral	0.0
LRP5	O75197-1.2	A1301N	Neutral	0.0
LRP5	O75197-1.2	A1301P	Neutral	0.0
LRP5	O75197-1.2	A1301Q	Neutral	0.0
LRP5	O75197-1.2	A1301R	Neutral	0.0
LRP5	O75197-1.2	A1301S	Neutral	0.0
LRP5	O75197-1.2	A1301T	Neutral	0.0
LRP5	O75197-1.2	A1301V	Neutral	0.0
LRP5	O75197-1.2	A1301W	Neutral	0.0
LRP5	O75197-1.2	A1301Y	Neutral	0.0
LRP5	O75197-1.2	Q1302A	Neutral	0.112
LRP5	O75197-1.2	Q1302C	Neutral	0.398
LRP5	O75197-1.2	Q1302D	Neutral	0.041
LRP5	O75197-1.2	Q1302E	Neutral	0.005
LRP5	O75197-1.2	Q1302F	Neutral	0.245
LRP5	O75197-1.2	Q1302G	Neutral	0.33
LRP5	O75197-1.2	Q1302H	Neutral	0.05
LRP5	O75197-1.2	Q1302I	Neutral	0.246
LRP5	O75197-1.2	Q1302K	Neutral	0.011
LRP5	O75197-1.2	Q1302L	Neutral	0.105
LRP5	O75197-1.2	Q1302M	Neutral	0.019
LRP5	O75197-1.2	Q1302N	Neutral	0.047
LRP5	O75197-1.2	Q1302P	Neutral	0.083
LRP5	O75197-1.2	Q1302R	Neutral	0.011
LRP5	O75197-1.2	Q1302S	Neutral	0.054
LRP5	O75197-1.2	Q1302T	Neutral	0.122
LRP5	O75197-1.2	Q1302V	Neutral	0.154
LRP5	O75197-1.2	Q1302W	Neutral	0.063
LRP5	O75197-1.2	Q1302Y	Neutral	0.068
LRP5	O75197-1.2	F1303A	Neutral	0.423
LRP5	O75197-1.2	F1303C	Pathogenic	0.58
LRP5	O75197-1.2	F1303D	Neutral	0.469
LRP5	O75197-1.2	F1303E	Pathogenic	0.506
LRP5	O75197-1.2	F1303G	Pathogenic	0.622
LRP5	O75197-1.2	F1303H	Neutral	0.183
LRP5	O75197-1.2	F1303I	Neutral	0.244
LRP5	O75197-1.2	F1303K	Neutral	0.438
LRP5	O75197-1.2	F1303L	Neutral	0.232
LRP5	O75197-1.2	F1303M	Neutral	0.165
LRP5	O75197-1.2	F1303N	Pathogenic	0.509
LRP5	O75197-1.2	F1303P	Pathogenic	0.91
LRP5	O75197-1.2	F1303Q	Pathogenic	0.6
LRP5	O75197-1.2	F1303R	Neutral	0.43
LRP5	O75197-1.2	F1303S	Neutral	0.352
LRP5	O75197-1.2	F1303T	Neutral	0.422
LRP5	O75197-1.2	F1303V	Neutral	0.366
LRP5	O75197-1.2	F1303W	Neutral	0.065
LRP5	O75197-1.2	F1303Y	Neutral	0.006
LRP5	O75197-1.2	P1304A	Neutral	0.0
LRP5	O75197-1.2	P1304C	Neutral	0.002
LRP5	O75197-1.2	P1304D	Neutral	0.0
LRP5	O75197-1.2	P1304E	Neutral	0.0
LRP5	O75197-1.2	P1304F	Neutral	0.003
LRP5	O75197-1.2	P1304G	Neutral	0.001
LRP5	O75197-1.2	P1304H	Neutral	0.001
LRP5	O75197-1.2	P1304I	Neutral	0.001
LRP5	O75197-1.2	P1304K	Neutral	0.0
LRP5	O75197-1.2	P1304L	Neutral	0.001
LRP5	O75197-1.2	P1304M	Neutral	0.001
LRP5	O75197-1.2	P1304N	Neutral	0.0
LRP5	O75197-1.2	P1304Q	Neutral	0.0
LRP5	O75197-1.2	P1304R	Neutral	0.0
LRP5	O75197-1.2	P1304S	Neutral	0.0
LRP5	O75197-1.2	P1304T	Neutral	0.0
LRP5	O75197-1.2	P1304V	Neutral	0.001
LRP5	O75197-1.2	P1304W	Neutral	0.002
LRP5	O75197-1.2	P1304Y	Neutral	0.002
LRP5	O75197-1.2	C1305A	Pathogenic	0.991
LRP5	O75197-1.2	C1305D	Pathogenic	0.999
LRP5	O75197-1.2	C1305E	Pathogenic	1.0
LRP5	O75197-1.2	C1305F	Pathogenic	0.999
LRP5	O75197-1.2	C1305G	Pathogenic	1.0
LRP5	O75197-1.2	C1305H	Pathogenic	1.0
LRP5	O75197-1.2	C1305I	Pathogenic	0.997
LRP5	O75197-1.2	C1305K	Pathogenic	0.999
LRP5	O75197-1.2	C1305L	Pathogenic	0.997
LRP5	O75197-1.2	C1305M	Pathogenic	0.998
LRP5	O75197-1.2	C1305N	Pathogenic	0.999
LRP5	O75197-1.2	C1305P	Pathogenic	1.0
LRP5	O75197-1.2	C1305Q	Pathogenic	0.999
LRP5	O75197-1.2	C1305R	Pathogenic	0.999
LRP5	O75197-1.2	C1305S	Pathogenic	0.996
LRP5	O75197-1.2	C1305T	Pathogenic	0.997
LRP5	O75197-1.2	C1305V	Pathogenic	0.998
LRP5	O75197-1.2	C1305W	Pathogenic	0.998
LRP5	O75197-1.2	C1305Y	Pathogenic	0.999
LRP5	O75197-1.2	A1306C	Neutral	0.0
LRP5	O75197-1.2	A1306D	Neutral	0.0
LRP5	O75197-1.2	A1306E	Neutral	0.0
LRP5	O75197-1.2	A1306F	Neutral	0.0
LRP5	O75197-1.2	A1306G	Neutral	0.0
LRP5	O75197-1.2	A1306H	Neutral	0.001
LRP5	O75197-1.2	A1306I	Neutral	0.0
LRP5	O75197-1.2	A1306K	Neutral	0.0
LRP5	O75197-1.2	A1306L	Neutral	0.0
LRP5	O75197-1.2	A1306M	Neutral	0.0
LRP5	O75197-1.2	A1306N	Neutral	0.0
LRP5	O75197-1.2	A1306P	Neutral	0.0
LRP5	O75197-1.2	A1306Q	Neutral	0.0
LRP5	O75197-1.2	A1306R	Neutral	0.0
LRP5	O75197-1.2	A1306S	Neutral	0.0
LRP5	O75197-1.2	A1306T	Neutral	0.0
LRP5	O75197-1.2	A1306V	Neutral	0.0
LRP5	O75197-1.2	A1306W	Neutral	0.0
LRP5	O75197-1.2	A1306Y	Neutral	0.0
LRP5	O75197-1.2	R1307A	Neutral	0.0
LRP5	O75197-1.2	R1307C	Neutral	0.0
LRP5	O75197-1.2	R1307D	Neutral	0.0
LRP5	O75197-1.2	R1307E	Neutral	0.0
LRP5	O75197-1.2	R1307F	Neutral	0.0
LRP5	O75197-1.2	R1307G	Neutral	0.0
LRP5	O75197-1.2	R1307H	Neutral	0.0
LRP5	O75197-1.2	R1307I	Neutral	0.0
LRP5	O75197-1.2	R1307K	Neutral	0.0
LRP5	O75197-1.2	R1307L	Neutral	0.0
LRP5	O75197-1.2	R1307M	Neutral	0.0
LRP5	O75197-1.2	R1307N	Neutral	0.0
LRP5	O75197-1.2	R1307P	Neutral	0.0
LRP5	O75197-1.2	R1307Q	Neutral	0.0
LRP5	O75197-1.2	R1307S	Neutral	0.0
LRP5	O75197-1.2	R1307T	Neutral	0.0
LRP5	O75197-1.2	R1307V	Neutral	0.0
LRP5	O75197-1.2	R1307W	Neutral	0.0
LRP5	O75197-1.2	R1307Y	Neutral	0.0
LRP5	O75197-1.2	G1308A	Neutral	0.007
LRP5	O75197-1.2	G1308C	Neutral	0.099
LRP5	O75197-1.2	G1308D	Neutral	0.014
LRP5	O75197-1.2	G1308E	Neutral	0.045
LRP5	O75197-1.2	G1308F	Neutral	0.047
LRP5	O75197-1.2	G1308H	Neutral	0.069
LRP5	O75197-1.2	G1308I	Neutral	0.131
LRP5	O75197-1.2	G1308K	Neutral	0.032
LRP5	O75197-1.2	G1308L	Neutral	0.142
LRP5	O75197-1.2	G1308M	Neutral	0.077
LRP5	O75197-1.2	G1308N	Neutral	0.005
LRP5	O75197-1.2	G1308P	Neutral	0.044
LRP5	O75197-1.2	G1308Q	Neutral	0.064
LRP5	O75197-1.2	G1308R	Neutral	0.031
LRP5	O75197-1.2	G1308S	Neutral	0.009
LRP5	O75197-1.2	G1308T	Neutral	0.064
LRP5	O75197-1.2	G1308V	Neutral	0.08
LRP5	O75197-1.2	G1308W	Neutral	0.01
LRP5	O75197-1.2	G1308Y	Neutral	0.093
LRP5	O75197-1.2	Q1309A	Neutral	0.035
LRP5	O75197-1.2	Q1309C	Neutral	0.16
LRP5	O75197-1.2	Q1309D	Neutral	0.012
LRP5	O75197-1.2	Q1309E	Neutral	0.002
LRP5	O75197-1.2	Q1309F	Neutral	0.086
LRP5	O75197-1.2	Q1309G	Neutral	0.124
LRP5	O75197-1.2	Q1309H	Neutral	0.015
LRP5	O75197-1.2	Q1309I	Neutral	0.086
LRP5	O75197-1.2	Q1309K	Neutral	0.003
LRP5	O75197-1.2	Q1309L	Neutral	0.033
LRP5	O75197-1.2	Q1309M	Neutral	0.006
LRP5	O75197-1.2	Q1309N	Neutral	0.014
LRP5	O75197-1.2	Q1309P	Neutral	0.026
LRP5	O75197-1.2	Q1309R	Neutral	0.003
LRP5	O75197-1.2	Q1309S	Neutral	0.016
LRP5	O75197-1.2	Q1309T	Neutral	0.038
LRP5	O75197-1.2	Q1309V	Neutral	0.05
LRP5	O75197-1.2	Q1309W	Neutral	0.019
LRP5	O75197-1.2	Q1309Y	Neutral	0.021
LRP5	O75197-1.2	C1310A	Pathogenic	0.992
LRP5	O75197-1.2	C1310D	Pathogenic	0.999
LRP5	O75197-1.2	C1310E	Pathogenic	1.0
LRP5	O75197-1.2	C1310F	Pathogenic	0.999
LRP5	O75197-1.2	C1310G	Pathogenic	1.0
LRP5	O75197-1.2	C1310H	Pathogenic	1.0
LRP5	O75197-1.2	C1310I	Pathogenic	0.997
LRP5	O75197-1.2	C1310K	Pathogenic	0.999
LRP5	O75197-1.2	C1310L	Pathogenic	0.997
LRP5	O75197-1.2	C1310M	Pathogenic	0.998
LRP5	O75197-1.2	C1310N	Pathogenic	0.999
LRP5	O75197-1.2	C1310P	Pathogenic	1.0
LRP5	O75197-1.2	C1310Q	Pathogenic	1.0
LRP5	O75197-1.2	C1310R	Pathogenic	0.999
LRP5	O75197-1.2	C1310S	Pathogenic	0.996
LRP5	O75197-1.2	C1310T	Pathogenic	0.997
LRP5	O75197-1.2	C1310V	Pathogenic	0.998
LRP5	O75197-1.2	C1310W	Pathogenic	0.998
LRP5	O75197-1.2	C1310Y	Pathogenic	0.999
LRP5	O75197-1.2	V1311A	Neutral	0.001
LRP5	O75197-1.2	V1311C	Neutral	0.004
LRP5	O75197-1.2	V1311D	Neutral	0.008
LRP5	O75197-1.2	V1311E	Neutral	0.003
LRP5	O75197-1.2	V1311F	Neutral	0.003
LRP5	O75197-1.2	V1311G	Neutral	0.015
LRP5	O75197-1.2	V1311H	Neutral	0.018
LRP5	O75197-1.2	V1311I	Neutral	0.0
LRP5	O75197-1.2	V1311K	Neutral	0.002
LRP5	O75197-1.2	V1311L	Neutral	0.0
LRP5	O75197-1.2	V1311M	Neutral	0.001
LRP5	O75197-1.2	V1311N	Neutral	0.009
LRP5	O75197-1.2	V1311P	Neutral	0.01
LRP5	O75197-1.2	V1311Q	Neutral	0.004
LRP5	O75197-1.2	V1311R	Neutral	0.006
LRP5	O75197-1.2	V1311S	Neutral	0.005
LRP5	O75197-1.2	V1311T	Neutral	0.001
LRP5	O75197-1.2	V1311W	Neutral	0.017
LRP5	O75197-1.2	V1311Y	Neutral	0.004
LRP5	O75197-1.2	D1312A	Neutral	0.063
LRP5	O75197-1.2	D1312C	Neutral	0.104
LRP5	O75197-1.2	D1312E	Neutral	0.002
LRP5	O75197-1.2	D1312F	Neutral	0.05
LRP5	O75197-1.2	D1312G	Neutral	0.028
LRP5	O75197-1.2	D1312H	Neutral	0.025
LRP5	O75197-1.2	D1312I	Neutral	0.05
LRP5	O75197-1.2	D1312K	Neutral	0.044
LRP5	O75197-1.2	D1312L	Neutral	0.151
LRP5	O75197-1.2	D1312M	Neutral	0.081
LRP5	O75197-1.2	D1312N	Neutral	0.006
LRP5	O75197-1.2	D1312P	Neutral	0.016
LRP5	O75197-1.2	D1312Q	Neutral	0.012
LRP5	O75197-1.2	D1312R	Neutral	0.12
LRP5	O75197-1.2	D1312S	Neutral	0.01
LRP5	O75197-1.2	D1312T	Neutral	0.024
LRP5	O75197-1.2	D1312V	Neutral	0.085
LRP5	O75197-1.2	D1312W	Neutral	0.092
LRP5	O75197-1.2	D1312Y	Neutral	0.099
LRP5	O75197-1.2	L1313A	Neutral	0.0
LRP5	O75197-1.2	L1313C	Neutral	0.0
LRP5	O75197-1.2	L1313D	Neutral	0.0
LRP5	O75197-1.2	L1313E	Neutral	0.0
LRP5	O75197-1.2	L1313F	Neutral	0.0
LRP5	O75197-1.2	L1313G	Neutral	0.0
LRP5	O75197-1.2	L1313H	Neutral	0.0
LRP5	O75197-1.2	L1313I	Neutral	0.0
LRP5	O75197-1.2	L1313K	Neutral	0.0
LRP5	O75197-1.2	L1313M	Neutral	0.0
LRP5	O75197-1.2	L1313N	Neutral	0.0
LRP5	O75197-1.2	L1313P	Neutral	0.0
LRP5	O75197-1.2	L1313Q	Neutral	0.0
LRP5	O75197-1.2	L1313R	Neutral	0.0
LRP5	O75197-1.2	L1313S	Neutral	0.0
LRP5	O75197-1.2	L1313T	Neutral	0.0
LRP5	O75197-1.2	L1313V	Neutral	0.0
LRP5	O75197-1.2	L1313W	Neutral	0.0
LRP5	O75197-1.2	L1313Y	Neutral	0.0
LRP5	O75197-1.2	R1314A	Neutral	0.0
LRP5	O75197-1.2	R1314C	Neutral	0.0
LRP5	O75197-1.2	R1314D	Neutral	0.0
LRP5	O75197-1.2	R1314E	Neutral	0.0
LRP5	O75197-1.2	R1314F	Neutral	0.0
LRP5	O75197-1.2	R1314G	Neutral	0.0
LRP5	O75197-1.2	R1314H	Neutral	0.0
LRP5	O75197-1.2	R1314I	Neutral	0.0
LRP5	O75197-1.2	R1314K	Neutral	0.0
LRP5	O75197-1.2	R1314L	Neutral	0.0
LRP5	O75197-1.2	R1314M	Neutral	0.0
LRP5	O75197-1.2	R1314N	Neutral	0.0
LRP5	O75197-1.2	R1314P	Neutral	0.0
LRP5	O75197-1.2	R1314Q	Neutral	0.0
LRP5	O75197-1.2	R1314S	Neutral	0.0
LRP5	O75197-1.2	R1314T	Neutral	0.0
LRP5	O75197-1.2	R1314V	Neutral	0.0
LRP5	O75197-1.2	R1314W	Neutral	0.0
LRP5	O75197-1.2	R1314Y	Neutral	0.0
LRP5	O75197-1.2	L1315A	Neutral	0.001
LRP5	O75197-1.2	L1315C	Neutral	0.002
LRP5	O75197-1.2	L1315D	Neutral	0.012
LRP5	O75197-1.2	L1315E	Neutral	0.005
LRP5	O75197-1.2	L1315F	Neutral	0.001
LRP5	O75197-1.2	L1315G	Neutral	0.022
LRP5	O75197-1.2	L1315H	Neutral	0.009
LRP5	O75197-1.2	L1315I	Neutral	0.0
LRP5	O75197-1.2	L1315K	Neutral	0.001
LRP5	O75197-1.2	L1315M	Neutral	0.0
LRP5	O75197-1.2	L1315N	Neutral	0.005
LRP5	O75197-1.2	L1315P	Neutral	0.015
LRP5	O75197-1.2	L1315Q	Neutral	0.002
LRP5	O75197-1.2	L1315R	Neutral	0.001
LRP5	O75197-1.2	L1315S	Neutral	0.002
LRP5	O75197-1.2	L1315T	Neutral	0.001
LRP5	O75197-1.2	L1315V	Neutral	0.0
LRP5	O75197-1.2	L1315W	Neutral	0.007
LRP5	O75197-1.2	L1315Y	Neutral	0.002
LRP5	O75197-1.2	R1316A	Neutral	0.008
LRP5	O75197-1.2	R1316C	Neutral	0.042
LRP5	O75197-1.2	R1316D	Neutral	0.065
LRP5	O75197-1.2	R1316E	Neutral	0.007
LRP5	O75197-1.2	R1316F	Neutral	0.022
LRP5	O75197-1.2	R1316G	Neutral	0.032
LRP5	O75197-1.2	R1316H	Neutral	0.003
LRP5	O75197-1.2	R1316I	Neutral	0.022
LRP5	O75197-1.2	R1316K	Neutral	0.001
LRP5	O75197-1.2	R1316L	Neutral	0.008
LRP5	O75197-1.2	R1316M	Neutral	0.004
LRP5	O75197-1.2	R1316N	Neutral	0.006
LRP5	O75197-1.2	R1316P	Neutral	0.018
LRP5	O75197-1.2	R1316Q	Neutral	0.002
LRP5	O75197-1.2	R1316S	Neutral	0.011
LRP5	O75197-1.2	R1316T	Neutral	0.009
LRP5	O75197-1.2	R1316V	Neutral	0.035
LRP5	O75197-1.2	R1316W	Neutral	0.015
LRP5	O75197-1.2	R1316Y	Neutral	0.016
LRP5	O75197-1.2	C1317A	Pathogenic	0.988
LRP5	O75197-1.2	C1317D	Pathogenic	0.999
LRP5	O75197-1.2	C1317E	Pathogenic	1.0
LRP5	O75197-1.2	C1317F	Pathogenic	0.998
LRP5	O75197-1.2	C1317G	Pathogenic	0.999
LRP5	O75197-1.2	C1317H	Pathogenic	0.999
LRP5	O75197-1.2	C1317I	Pathogenic	0.995
LRP5	O75197-1.2	C1317K	Pathogenic	0.999
LRP5	O75197-1.2	C1317L	Pathogenic	0.996
LRP5	O75197-1.2	C1317M	Pathogenic	0.997
LRP5	O75197-1.2	C1317N	Pathogenic	0.999
LRP5	O75197-1.2	C1317P	Pathogenic	1.0
LRP5	O75197-1.2	C1317Q	Pathogenic	0.999
LRP5	O75197-1.2	C1317R	Pathogenic	0.999
LRP5	O75197-1.2	C1317S	Pathogenic	0.995
LRP5	O75197-1.2	C1317T	Pathogenic	0.996
LRP5	O75197-1.2	C1317V	Pathogenic	0.997
LRP5	O75197-1.2	C1317W	Pathogenic	0.998
LRP5	O75197-1.2	C1317Y	Pathogenic	0.999
LRP5	O75197-1.2	D1318A	Neutral	0.002
LRP5	O75197-1.2	D1318C	Neutral	0.004
LRP5	O75197-1.2	D1318E	Neutral	0.0
LRP5	O75197-1.2	D1318F	Neutral	0.002
LRP5	O75197-1.2	D1318G	Neutral	0.001
LRP5	O75197-1.2	D1318H	Neutral	0.001
LRP5	O75197-1.2	D1318I	Neutral	0.002
LRP5	O75197-1.2	D1318K	Neutral	0.002
LRP5	O75197-1.2	D1318L	Neutral	0.006
LRP5	O75197-1.2	D1318M	Neutral	0.003
LRP5	O75197-1.2	D1318N	Neutral	0.0
LRP5	O75197-1.2	D1318P	Neutral	0.001
LRP5	O75197-1.2	D1318Q	Neutral	0.0
LRP5	O75197-1.2	D1318R	Neutral	0.005
LRP5	O75197-1.2	D1318S	Neutral	0.0
LRP5	O75197-1.2	D1318T	Neutral	0.001
LRP5	O75197-1.2	D1318V	Neutral	0.003
LRP5	O75197-1.2	D1318W	Neutral	0.004
LRP5	O75197-1.2	D1318Y	Neutral	0.004
LRP5	O75197-1.2	G1319A	Neutral	0.035
LRP5	O75197-1.2	G1319C	Neutral	0.349
LRP5	O75197-1.2	G1319D	Neutral	0.065
LRP5	O75197-1.2	G1319E	Neutral	0.187
LRP5	O75197-1.2	G1319F	Neutral	0.194
LRP5	O75197-1.2	G1319H	Neutral	0.263
LRP5	O75197-1.2	G1319I	Neutral	0.424
LRP5	O75197-1.2	G1319K	Neutral	0.139
LRP5	O75197-1.2	G1319L	Neutral	0.446
LRP5	O75197-1.2	G1319M	Neutral	0.287
LRP5	O75197-1.2	G1319N	Neutral	0.026
LRP5	O75197-1.2	G1319P	Neutral	0.181
LRP5	O75197-1.2	G1319Q	Neutral	0.25
LRP5	O75197-1.2	G1319R	Neutral	0.135
LRP5	O75197-1.2	G1319S	Neutral	0.043
LRP5	O75197-1.2	G1319T	Neutral	0.25
LRP5	O75197-1.2	G1319V	Neutral	0.296
LRP5	O75197-1.2	G1319W	Neutral	0.048
LRP5	O75197-1.2	G1319Y	Neutral	0.333
LRP5	O75197-1.2	E1320A	Neutral	0.001
LRP5	O75197-1.2	E1320C	Neutral	0.013
LRP5	O75197-1.2	E1320D	Neutral	0.0
LRP5	O75197-1.2	E1320F	Neutral	0.002
LRP5	O75197-1.2	E1320G	Neutral	0.003
LRP5	O75197-1.2	E1320H	Neutral	0.0
LRP5	O75197-1.2	E1320I	Neutral	0.002
LRP5	O75197-1.2	E1320K	Neutral	0.0
LRP5	O75197-1.2	E1320L	Neutral	0.002
LRP5	O75197-1.2	E1320M	Neutral	0.001
LRP5	O75197-1.2	E1320N	Neutral	0.001
LRP5	O75197-1.2	E1320P	Neutral	0.001
LRP5	O75197-1.2	E1320Q	Neutral	0.0
LRP5	O75197-1.2	E1320R	Neutral	0.0
LRP5	O75197-1.2	E1320S	Neutral	0.0
LRP5	O75197-1.2	E1320T	Neutral	0.001
LRP5	O75197-1.2	E1320V	Neutral	0.001
LRP5	O75197-1.2	E1320W	Neutral	0.001
LRP5	O75197-1.2	E1320Y	Neutral	0.001
LRP5	O75197-1.2	A1321C	Neutral	0.0
LRP5	O75197-1.2	A1321D	Neutral	0.0
LRP5	O75197-1.2	A1321E	Neutral	0.0
LRP5	O75197-1.2	A1321F	Neutral	0.0
LRP5	O75197-1.2	A1321G	Neutral	0.0
LRP5	O75197-1.2	A1321H	Neutral	0.0
LRP5	O75197-1.2	A1321I	Neutral	0.0
LRP5	O75197-1.2	A1321K	Neutral	0.0
LRP5	O75197-1.2	A1321L	Neutral	0.0
LRP5	O75197-1.2	A1321M	Neutral	0.0
LRP5	O75197-1.2	A1321N	Neutral	0.0
LRP5	O75197-1.2	A1321P	Neutral	0.0
LRP5	O75197-1.2	A1321Q	Neutral	0.0
LRP5	O75197-1.2	A1321R	Neutral	0.0
LRP5	O75197-1.2	A1321S	Neutral	0.0
LRP5	O75197-1.2	A1321T	Neutral	0.0
LRP5	O75197-1.2	A1321V	Neutral	0.0
LRP5	O75197-1.2	A1321W	Neutral	0.0
LRP5	O75197-1.2	A1321Y	Neutral	0.0
LRP5	O75197-1.2	D1322A	Neutral	0.001
LRP5	O75197-1.2	D1322C	Neutral	0.002
LRP5	O75197-1.2	D1322E	Neutral	0.0
LRP5	O75197-1.2	D1322F	Neutral	0.001
LRP5	O75197-1.2	D1322G	Neutral	0.0
LRP5	O75197-1.2	D1322H	Neutral	0.0
LRP5	O75197-1.2	D1322I	Neutral	0.001
LRP5	O75197-1.2	D1322K	Neutral	0.001
LRP5	O75197-1.2	D1322L	Neutral	0.003
LRP5	O75197-1.2	D1322M	Neutral	0.001
LRP5	O75197-1.2	D1322N	Neutral	0.0
LRP5	O75197-1.2	D1322P	Neutral	0.0
LRP5	O75197-1.2	D1322Q	Neutral	0.0
LRP5	O75197-1.2	D1322R	Neutral	0.002
LRP5	O75197-1.2	D1322S	Neutral	0.0
LRP5	O75197-1.2	D1322T	Neutral	0.0
LRP5	O75197-1.2	D1322V	Neutral	0.002
LRP5	O75197-1.2	D1322W	Neutral	0.002
LRP5	O75197-1.2	D1322Y	Neutral	0.002
LRP5	O75197-1.2	C1323A	Pathogenic	0.988
LRP5	O75197-1.2	C1323D	Pathogenic	0.999
LRP5	O75197-1.2	C1323E	Pathogenic	1.0
LRP5	O75197-1.2	C1323F	Pathogenic	0.998
LRP5	O75197-1.2	C1323G	Pathogenic	0.999
LRP5	O75197-1.2	C1323H	Pathogenic	0.999
LRP5	O75197-1.2	C1323I	Pathogenic	0.995
LRP5	O75197-1.2	C1323K	Pathogenic	0.999
LRP5	O75197-1.2	C1323L	Pathogenic	0.996
LRP5	O75197-1.2	C1323M	Pathogenic	0.997
LRP5	O75197-1.2	C1323N	Pathogenic	0.999
LRP5	O75197-1.2	C1323P	Pathogenic	1.0
LRP5	O75197-1.2	C1323Q	Pathogenic	0.999
LRP5	O75197-1.2	C1323R	Pathogenic	0.998
LRP5	O75197-1.2	C1323S	Pathogenic	0.994
LRP5	O75197-1.2	C1323T	Pathogenic	0.996
LRP5	O75197-1.2	C1323V	Pathogenic	0.997
LRP5	O75197-1.2	C1323W	Pathogenic	0.997
LRP5	O75197-1.2	C1323Y	Pathogenic	0.999
LRP5	O75197-1.2	Q1324A	Neutral	0.002
LRP5	O75197-1.2	Q1324C	Neutral	0.012
LRP5	O75197-1.2	Q1324D	Neutral	0.001
LRP5	O75197-1.2	Q1324E	Neutral	0.0
LRP5	O75197-1.2	Q1324F	Neutral	0.006
LRP5	O75197-1.2	Q1324G	Neutral	0.009
LRP5	O75197-1.2	Q1324H	Neutral	0.001
LRP5	O75197-1.2	Q1324I	Neutral	0.006
LRP5	O75197-1.2	Q1324K	Neutral	0.0
LRP5	O75197-1.2	Q1324L	Neutral	0.002
LRP5	O75197-1.2	Q1324M	Neutral	0.0
LRP5	O75197-1.2	Q1324N	Neutral	0.001
LRP5	O75197-1.2	Q1324P	Neutral	0.002
LRP5	O75197-1.2	Q1324R	Neutral	0.0
LRP5	O75197-1.2	Q1324S	Neutral	0.001
LRP5	O75197-1.2	Q1324T	Neutral	0.002
LRP5	O75197-1.2	Q1324V	Neutral	0.003
LRP5	O75197-1.2	Q1324W	Neutral	0.001
LRP5	O75197-1.2	Q1324Y	Neutral	0.001
LRP5	O75197-1.2	D1325A	Neutral	0.157
LRP5	O75197-1.2	D1325C	Neutral	0.243
LRP5	O75197-1.2	D1325E	Neutral	0.005
LRP5	O75197-1.2	D1325F	Neutral	0.128
LRP5	O75197-1.2	D1325G	Neutral	0.073
LRP5	O75197-1.2	D1325H	Neutral	0.067
LRP5	O75197-1.2	D1325I	Neutral	0.128
LRP5	O75197-1.2	D1325K	Neutral	0.113
LRP5	O75197-1.2	D1325L	Neutral	0.329
LRP5	O75197-1.2	D1325M	Neutral	0.197
LRP5	O75197-1.2	D1325N	Neutral	0.015
LRP5	O75197-1.2	D1325P	Neutral	0.042
LRP5	O75197-1.2	D1325Q	Neutral	0.031
LRP5	O75197-1.2	D1325R	Neutral	0.273
LRP5	O75197-1.2	D1325S	Neutral	0.027
LRP5	O75197-1.2	D1325T	Neutral	0.062
LRP5	O75197-1.2	D1325V	Neutral	0.204
LRP5	O75197-1.2	D1325W	Neutral	0.22
LRP5	O75197-1.2	D1325Y	Neutral	0.233
LRP5	O75197-1.2	R1326A	Neutral	0.0
LRP5	O75197-1.2	R1326C	Neutral	0.0
LRP5	O75197-1.2	R1326D	Neutral	0.0
LRP5	O75197-1.2	R1326E	Neutral	0.0
LRP5	O75197-1.2	R1326F	Neutral	0.0
LRP5	O75197-1.2	R1326G	Neutral	0.0
LRP5	O75197-1.2	R1326H	Neutral	0.0
LRP5	O75197-1.2	R1326I	Neutral	0.0
LRP5	O75197-1.2	R1326K	Neutral	0.0
LRP5	O75197-1.2	R1326L	Neutral	0.0
LRP5	O75197-1.2	R1326M	Neutral	0.0
LRP5	O75197-1.2	R1326N	Neutral	0.0
LRP5	O75197-1.2	R1326P	Neutral	0.0
LRP5	O75197-1.2	R1326Q	Neutral	0.0
LRP5	O75197-1.2	R1326S	Neutral	0.0
LRP5	O75197-1.2	R1326T	Neutral	0.0
LRP5	O75197-1.2	R1326V	Neutral	0.0
LRP5	O75197-1.2	R1326W	Neutral	0.0
LRP5	O75197-1.2	R1326Y	Neutral	0.0
LRP5	O75197-1.2	S1327A	Neutral	0.006
LRP5	O75197-1.2	S1327C	Neutral	0.031
LRP5	O75197-1.2	S1327D	Neutral	0.013
LRP5	O75197-1.2	S1327E	Neutral	0.014
LRP5	O75197-1.2	S1327F	Neutral	0.042
LRP5	O75197-1.2	S1327G	Neutral	0.024
LRP5	O75197-1.2	S1327H	Neutral	0.061
LRP5	O75197-1.2	S1327I	Neutral	0.042
LRP5	O75197-1.2	S1327K	Neutral	0.01
LRP5	O75197-1.2	S1327L	Neutral	0.046
LRP5	O75197-1.2	S1327M	Neutral	0.023
LRP5	O75197-1.2	S1327N	Neutral	0.005
LRP5	O75197-1.2	S1327P	Neutral	0.039
LRP5	O75197-1.2	S1327Q	Neutral	0.021
LRP5	O75197-1.2	S1327R	Neutral	0.029
LRP5	O75197-1.2	S1327T	Neutral	0.006
LRP5	O75197-1.2	S1327V	Neutral	0.071
LRP5	O75197-1.2	S1327W	Neutral	0.078
LRP5	O75197-1.2	S1327Y	Neutral	0.083
LRP5	O75197-1.2	D1328A	Neutral	0.163
LRP5	O75197-1.2	D1328C	Neutral	0.251
LRP5	O75197-1.2	D1328E	Neutral	0.005
LRP5	O75197-1.2	D1328F	Neutral	0.133
LRP5	O75197-1.2	D1328G	Neutral	0.076
LRP5	O75197-1.2	D1328H	Neutral	0.07
LRP5	O75197-1.2	D1328I	Neutral	0.133
LRP5	O75197-1.2	D1328K	Neutral	0.118
LRP5	O75197-1.2	D1328L	Neutral	0.339
LRP5	O75197-1.2	D1328M	Neutral	0.204
LRP5	O75197-1.2	D1328N	Neutral	0.016
LRP5	O75197-1.2	D1328P	Neutral	0.044
LRP5	O75197-1.2	D1328Q	Neutral	0.033
LRP5	O75197-1.2	D1328R	Neutral	0.283
LRP5	O75197-1.2	D1328S	Neutral	0.028
LRP5	O75197-1.2	D1328T	Neutral	0.065
LRP5	O75197-1.2	D1328V	Neutral	0.211
LRP5	O75197-1.2	D1328W	Neutral	0.228
LRP5	O75197-1.2	D1328Y	Neutral	0.241
LRP5	O75197-1.2	E1329A	Neutral	0.115
LRP5	O75197-1.2	E1329C	Pathogenic	0.674
LRP5	O75197-1.2	E1329D	Neutral	0.01
LRP5	O75197-1.2	E1329F	Neutral	0.247
LRP5	O75197-1.2	E1329G	Neutral	0.336
LRP5	O75197-1.2	E1329H	Neutral	0.05
LRP5	O75197-1.2	E1329I	Neutral	0.248
LRP5	O75197-1.2	E1329K	Neutral	0.024
LRP5	O75197-1.2	E1329L	Neutral	0.265
LRP5	O75197-1.2	E1329M	Neutral	0.153
LRP5	O75197-1.2	E1329N	Neutral	0.092
LRP5	O75197-1.2	E1329P	Neutral	0.085
LRP5	O75197-1.2	E1329Q	Neutral	0.008
LRP5	O75197-1.2	E1329R	Neutral	0.067
LRP5	O75197-1.2	E1329S	Neutral	0.055
LRP5	O75197-1.2	E1329T	Neutral	0.124
LRP5	O75197-1.2	E1329V	Neutral	0.157
LRP5	O75197-1.2	E1329W	Neutral	0.172
LRP5	O75197-1.2	E1329Y	Neutral	0.183
LRP5	O75197-1.2	A1330C	Neutral	0.0
LRP5	O75197-1.2	A1330D	Neutral	0.0
LRP5	O75197-1.2	A1330E	Neutral	0.0
LRP5	O75197-1.2	A1330F	Neutral	0.0
LRP5	O75197-1.2	A1330G	Neutral	0.0
LRP5	O75197-1.2	A1330H	Neutral	0.0
LRP5	O75197-1.2	A1330I	Neutral	0.0
LRP5	O75197-1.2	A1330K	Neutral	0.0
LRP5	O75197-1.2	A1330L	Neutral	0.0
LRP5	O75197-1.2	A1330M	Neutral	0.0
LRP5	O75197-1.2	A1330N	Neutral	0.0
LRP5	O75197-1.2	A1330P	Neutral	0.0
LRP5	O75197-1.2	A1330Q	Neutral	0.0
LRP5	O75197-1.2	A1330R	Neutral	0.0
LRP5	O75197-1.2	A1330S	Neutral	0.0
LRP5	O75197-1.2	A1330T	Neutral	0.0
LRP5	O75197-1.2	A1330V	Neutral	0.0
LRP5	O75197-1.2	A1330W	Neutral	0.0
LRP5	O75197-1.2	A1330Y	Neutral	0.0
LRP5	O75197-1.2	D1331A	Neutral	0.0
LRP5	O75197-1.2	D1331C	Neutral	0.0
LRP5	O75197-1.2	D1331E	Neutral	0.0
LRP5	O75197-1.2	D1331F	Neutral	0.0
LRP5	O75197-1.2	D1331G	Neutral	0.0
LRP5	O75197-1.2	D1331H	Neutral	0.0
LRP5	O75197-1.2	D1331I	Neutral	0.0
LRP5	O75197-1.2	D1331K	Neutral	0.0
LRP5	O75197-1.2	D1331L	Neutral	0.0
LRP5	O75197-1.2	D1331M	Neutral	0.0
LRP5	O75197-1.2	D1331N	Neutral	0.0
LRP5	O75197-1.2	D1331P	Neutral	0.0
LRP5	O75197-1.2	D1331Q	Neutral	0.0
LRP5	O75197-1.2	D1331R	Neutral	0.0
LRP5	O75197-1.2	D1331S	Neutral	0.0
LRP5	O75197-1.2	D1331T	Neutral	0.0
LRP5	O75197-1.2	D1331V	Neutral	0.0
LRP5	O75197-1.2	D1331W	Neutral	0.0
LRP5	O75197-1.2	D1331Y	Neutral	0.0
LRP5	O75197-1.2	C1332A	Pathogenic	0.983
LRP5	O75197-1.2	C1332D	Pathogenic	0.998
LRP5	O75197-1.2	C1332E	Pathogenic	1.0
LRP5	O75197-1.2	C1332F	Pathogenic	0.998
LRP5	O75197-1.2	C1332G	Pathogenic	0.999
LRP5	O75197-1.2	C1332H	Pathogenic	0.999
LRP5	O75197-1.2	C1332I	Pathogenic	0.993
LRP5	O75197-1.2	C1332K	Pathogenic	0.998
LRP5	O75197-1.2	C1332L	Pathogenic	0.994
LRP5	O75197-1.2	C1332M	Pathogenic	0.996
LRP5	O75197-1.2	C1332N	Pathogenic	0.999
LRP5	O75197-1.2	C1332P	Pathogenic	1.0
LRP5	O75197-1.2	C1332Q	Pathogenic	0.999
LRP5	O75197-1.2	C1332R	Pathogenic	0.998
LRP5	O75197-1.2	C1332S	Pathogenic	0.993
LRP5	O75197-1.2	C1332T	Pathogenic	0.994
LRP5	O75197-1.2	C1332V	Pathogenic	0.996
LRP5	O75197-1.2	C1332W	Pathogenic	0.997
LRP5	O75197-1.2	C1332Y	Pathogenic	0.999
LRP5	O75197-1.2	D1333A	Neutral	0.0
LRP5	O75197-1.2	D1333C	Neutral	0.001
LRP5	O75197-1.2	D1333E	Neutral	0.0
LRP5	O75197-1.2	D1333F	Neutral	0.0
LRP5	O75197-1.2	D1333G	Neutral	0.0
LRP5	O75197-1.2	D1333H	Neutral	0.0
LRP5	O75197-1.2	D1333I	Neutral	0.0
LRP5	O75197-1.2	D1333K	Neutral	0.0
LRP5	O75197-1.2	D1333L	Neutral	0.001
LRP5	O75197-1.2	D1333M	Neutral	0.0
LRP5	O75197-1.2	D1333N	Neutral	0.0
LRP5	O75197-1.2	D1333P	Neutral	0.0
LRP5	O75197-1.2	D1333Q	Neutral	0.0
LRP5	O75197-1.2	D1333R	Neutral	0.001
LRP5	O75197-1.2	D1333S	Neutral	0.0
LRP5	O75197-1.2	D1333T	Neutral	0.0
LRP5	O75197-1.2	D1333V	Neutral	0.0
LRP5	O75197-1.2	D1333W	Neutral	0.001
LRP5	O75197-1.2	D1333Y	Neutral	0.001
LRP5	O75197-1.2	A1334C	Neutral	0.0
LRP5	O75197-1.2	A1334D	Neutral	0.0
LRP5	O75197-1.2	A1334E	Neutral	0.0
LRP5	O75197-1.2	A1334F	Neutral	0.0
LRP5	O75197-1.2	A1334G	Neutral	0.0
LRP5	O75197-1.2	A1334H	Neutral	0.0
LRP5	O75197-1.2	A1334I	Neutral	0.0
LRP5	O75197-1.2	A1334K	Neutral	0.0
LRP5	O75197-1.2	A1334L	Neutral	0.0
LRP5	O75197-1.2	A1334M	Neutral	0.0
LRP5	O75197-1.2	A1334N	Neutral	0.0
LRP5	O75197-1.2	A1334P	Neutral	0.0
LRP5	O75197-1.2	A1334Q	Neutral	0.0
LRP5	O75197-1.2	A1334R	Neutral	0.0
LRP5	O75197-1.2	A1334S	Neutral	0.0
LRP5	O75197-1.2	A1334T	Neutral	0.0
LRP5	O75197-1.2	A1334V	Neutral	0.0
LRP5	O75197-1.2	A1334W	Neutral	0.0
LRP5	O75197-1.2	A1334Y	Neutral	0.0
LRP5	O75197-1.2	I1335A	Neutral	0.0
LRP5	O75197-1.2	I1335C	Neutral	0.0
LRP5	O75197-1.2	I1335D	Neutral	0.0
LRP5	O75197-1.2	I1335E	Neutral	0.0
LRP5	O75197-1.2	I1335F	Neutral	0.0
LRP5	O75197-1.2	I1335G	Neutral	0.0
LRP5	O75197-1.2	I1335H	Neutral	0.0
LRP5	O75197-1.2	I1335K	Neutral	0.0
LRP5	O75197-1.2	I1335L	Neutral	0.0
LRP5	O75197-1.2	I1335M	Neutral	0.0
LRP5	O75197-1.2	I1335N	Neutral	0.0
LRP5	O75197-1.2	I1335P	Neutral	0.0
LRP5	O75197-1.2	I1335Q	Neutral	0.0
LRP5	O75197-1.2	I1335R	Neutral	0.0
LRP5	O75197-1.2	I1335S	Neutral	0.0
LRP5	O75197-1.2	I1335T	Neutral	0.0
LRP5	O75197-1.2	I1335V	Neutral	0.0
LRP5	O75197-1.2	I1335W	Neutral	0.001
LRP5	O75197-1.2	I1335Y	Neutral	0.0
LRP5	O75197-1.2	C1336A	Pathogenic	0.961
LRP5	O75197-1.2	C1336D	Pathogenic	0.996
LRP5	O75197-1.2	C1336E	Pathogenic	0.999
LRP5	O75197-1.2	C1336F	Pathogenic	0.995
LRP5	O75197-1.2	C1336G	Pathogenic	0.998
LRP5	O75197-1.2	C1336H	Pathogenic	0.998
LRP5	O75197-1.2	C1336I	Pathogenic	0.985
LRP5	O75197-1.2	C1336K	Pathogenic	0.995
LRP5	O75197-1.2	C1336L	Pathogenic	0.986
LRP5	O75197-1.2	C1336M	Pathogenic	0.991
LRP5	O75197-1.2	C1336N	Pathogenic	0.997
LRP5	O75197-1.2	C1336P	Pathogenic	0.999
LRP5	O75197-1.2	C1336Q	Pathogenic	0.998
LRP5	O75197-1.2	C1336R	Pathogenic	0.995
LRP5	O75197-1.2	C1336S	Pathogenic	0.983
LRP5	O75197-1.2	C1336T	Pathogenic	0.987
LRP5	O75197-1.2	C1336V	Pathogenic	0.991
LRP5	O75197-1.2	C1336W	Pathogenic	0.992
LRP5	O75197-1.2	C1336Y	Pathogenic	0.997
LRP5	O75197-1.2	L1337A	Neutral	0.0
LRP5	O75197-1.2	L1337C	Neutral	0.001
LRP5	O75197-1.2	L1337D	Neutral	0.004
LRP5	O75197-1.2	L1337E	Neutral	0.002
LRP5	O75197-1.2	L1337F	Neutral	0.0
LRP5	O75197-1.2	L1337G	Neutral	0.007
LRP5	O75197-1.2	L1337H	Neutral	0.003
LRP5	O75197-1.2	L1337I	Neutral	0.0
LRP5	O75197-1.2	L1337K	Neutral	0.0
LRP5	O75197-1.2	L1337M	Neutral	0.0
LRP5	O75197-1.2	L1337N	Neutral	0.002
LRP5	O75197-1.2	L1337P	Neutral	0.005
LRP5	O75197-1.2	L1337Q	Neutral	0.001
LRP5	O75197-1.2	L1337R	Neutral	0.0
LRP5	O75197-1.2	L1337S	Neutral	0.001
LRP5	O75197-1.2	L1337T	Neutral	0.0
LRP5	O75197-1.2	L1337V	Neutral	0.0
LRP5	O75197-1.2	L1337W	Neutral	0.002
LRP5	O75197-1.2	L1337Y	Neutral	0.001
LRP5	O75197-1.2	P1338A	Neutral	0.0
LRP5	O75197-1.2	P1338C	Neutral	0.002
LRP5	O75197-1.2	P1338D	Neutral	0.0
LRP5	O75197-1.2	P1338E	Neutral	0.0
LRP5	O75197-1.2	P1338F	Neutral	0.003
LRP5	O75197-1.2	P1338G	Neutral	0.0
LRP5	O75197-1.2	P1338H	Neutral	0.001
LRP5	O75197-1.2	P1338I	Neutral	0.001
LRP5	O75197-1.2	P1338K	Neutral	0.0
LRP5	O75197-1.2	P1338L	Neutral	0.001
LRP5	O75197-1.2	P1338M	Neutral	0.001
LRP5	O75197-1.2	P1338N	Neutral	0.0
LRP5	O75197-1.2	P1338Q	Neutral	0.0
LRP5	O75197-1.2	P1338R	Neutral	0.0
LRP5	O75197-1.2	P1338S	Neutral	0.0
LRP5	O75197-1.2	P1338T	Neutral	0.0
LRP5	O75197-1.2	P1338V	Neutral	0.001
LRP5	O75197-1.2	P1338W	Neutral	0.002
LRP5	O75197-1.2	P1338Y	Neutral	0.002
LRP5	O75197-1.2	N1339A	Neutral	0.001
LRP5	O75197-1.2	N1339C	Neutral	0.002
LRP5	O75197-1.2	N1339D	Neutral	0.0
LRP5	O75197-1.2	N1339E	Neutral	0.0
LRP5	O75197-1.2	N1339F	Neutral	0.001
LRP5	O75197-1.2	N1339G	Neutral	0.0
LRP5	O75197-1.2	N1339H	Neutral	0.0
LRP5	O75197-1.2	N1339I	Neutral	0.001
LRP5	O75197-1.2	N1339K	Neutral	0.0
LRP5	O75197-1.2	N1339L	Neutral	0.001
LRP5	O75197-1.2	N1339M	Neutral	0.001
LRP5	O75197-1.2	N1339P	Neutral	0.001
LRP5	O75197-1.2	N1339Q	Neutral	0.0
LRP5	O75197-1.2	N1339R	Neutral	0.0
LRP5	O75197-1.2	N1339S	Neutral	0.0
LRP5	O75197-1.2	N1339T	Neutral	0.0
LRP5	O75197-1.2	N1339V	Neutral	0.002
LRP5	O75197-1.2	N1339W	Neutral	0.002
LRP5	O75197-1.2	N1339Y	Neutral	0.001
LRP5	O75197-1.2	Q1340A	Neutral	0.03
LRP5	O75197-1.2	Q1340C	Neutral	0.141
LRP5	O75197-1.2	Q1340D	Neutral	0.01
LRP5	O75197-1.2	Q1340E	Neutral	0.001
LRP5	O75197-1.2	Q1340F	Neutral	0.074
LRP5	O75197-1.2	Q1340G	Neutral	0.108
LRP5	O75197-1.2	Q1340H	Neutral	0.013
LRP5	O75197-1.2	Q1340I	Neutral	0.075
LRP5	O75197-1.2	Q1340K	Neutral	0.003
LRP5	O75197-1.2	Q1340L	Neutral	0.028
LRP5	O75197-1.2	Q1340M	Neutral	0.005
LRP5	O75197-1.2	Q1340N	Neutral	0.012
LRP5	O75197-1.2	Q1340P	Neutral	0.022
LRP5	O75197-1.2	Q1340R	Neutral	0.003
LRP5	O75197-1.2	Q1340S	Neutral	0.014
LRP5	O75197-1.2	Q1340T	Neutral	0.033
LRP5	O75197-1.2	Q1340V	Neutral	0.043
LRP5	O75197-1.2	Q1340W	Neutral	0.016
LRP5	O75197-1.2	Q1340Y	Neutral	0.018
LRP5	O75197-1.2	F1341A	Neutral	0.109
LRP5	O75197-1.2	F1341C	Neutral	0.188
LRP5	O75197-1.2	F1341D	Neutral	0.129
LRP5	O75197-1.2	F1341E	Neutral	0.146
LRP5	O75197-1.2	F1341G	Neutral	0.215
LRP5	O75197-1.2	F1341H	Neutral	0.036
LRP5	O75197-1.2	F1341I	Neutral	0.051
LRP5	O75197-1.2	F1341K	Neutral	0.115
LRP5	O75197-1.2	F1341L	Neutral	0.048
LRP5	O75197-1.2	F1341M	Neutral	0.032
LRP5	O75197-1.2	F1341N	Neutral	0.148
LRP5	O75197-1.2	F1341P	Pathogenic	0.63
LRP5	O75197-1.2	F1341Q	Neutral	0.201
LRP5	O75197-1.2	F1341R	Neutral	0.112
LRP5	O75197-1.2	F1341S	Neutral	0.083
LRP5	O75197-1.2	F1341T	Neutral	0.109
LRP5	O75197-1.2	F1341V	Neutral	0.088
LRP5	O75197-1.2	F1341W	Neutral	0.011
LRP5	O75197-1.2	F1341Y	Neutral	0.001
LRP5	O75197-1.2	R1342A	Neutral	0.001
LRP5	O75197-1.2	R1342C	Neutral	0.003
LRP5	O75197-1.2	R1342D	Neutral	0.005
LRP5	O75197-1.2	R1342E	Neutral	0.0
LRP5	O75197-1.2	R1342F	Neutral	0.002
LRP5	O75197-1.2	R1342G	Neutral	0.002
LRP5	O75197-1.2	R1342H	Neutral	0.0
LRP5	O75197-1.2	R1342I	Neutral	0.002
LRP5	O75197-1.2	R1342K	Neutral	0.0
LRP5	O75197-1.2	R1342L	Neutral	0.001
LRP5	O75197-1.2	R1342M	Neutral	0.0
LRP5	O75197-1.2	R1342N	Neutral	0.0
LRP5	O75197-1.2	R1342P	Neutral	0.001
LRP5	O75197-1.2	R1342Q	Neutral	0.0
LRP5	O75197-1.2	R1342S	Neutral	0.001
LRP5	O75197-1.2	R1342T	Neutral	0.001
LRP5	O75197-1.2	R1342V	Neutral	0.002
LRP5	O75197-1.2	R1342W	Neutral	0.001
LRP5	O75197-1.2	R1342Y	Neutral	0.001
LRP5	O75197-1.2	C1343A	Pathogenic	0.992
LRP5	O75197-1.2	C1343D	Pathogenic	0.999
LRP5	O75197-1.2	C1343E	Pathogenic	1.0
LRP5	O75197-1.2	C1343F	Pathogenic	0.999
LRP5	O75197-1.2	C1343G	Pathogenic	1.0
LRP5	O75197-1.2	C1343H	Pathogenic	1.0
LRP5	O75197-1.2	C1343I	Pathogenic	0.997
LRP5	O75197-1.2	C1343K	Pathogenic	0.999
LRP5	O75197-1.2	C1343L	Pathogenic	0.997
LRP5	O75197-1.2	C1343M	Pathogenic	0.998
LRP5	O75197-1.2	C1343N	Pathogenic	0.999
LRP5	O75197-1.2	C1343P	Pathogenic	1.0
LRP5	O75197-1.2	C1343Q	Pathogenic	1.0
LRP5	O75197-1.2	C1343R	Pathogenic	0.999
LRP5	O75197-1.2	C1343S	Pathogenic	0.996
LRP5	O75197-1.2	C1343T	Pathogenic	0.997
LRP5	O75197-1.2	C1343V	Pathogenic	0.998
LRP5	O75197-1.2	C1343W	Pathogenic	0.998
LRP5	O75197-1.2	C1343Y	Pathogenic	0.999
LRP5	O75197-1.2	A1344C	Neutral	0.0
LRP5	O75197-1.2	A1344D	Neutral	0.002
LRP5	O75197-1.2	A1344E	Neutral	0.001
LRP5	O75197-1.2	A1344F	Neutral	0.001
LRP5	O75197-1.2	A1344G	Neutral	0.0
LRP5	O75197-1.2	A1344H	Neutral	0.005
LRP5	O75197-1.2	A1344I	Neutral	0.0
LRP5	O75197-1.2	A1344K	Neutral	0.001
LRP5	O75197-1.2	A1344L	Neutral	0.001
LRP5	O75197-1.2	A1344M	Neutral	0.001
LRP5	O75197-1.2	A1344N	Neutral	0.003
LRP5	O75197-1.2	A1344P	Neutral	0.001
LRP5	O75197-1.2	A1344Q	Neutral	0.001
LRP5	O75197-1.2	A1344R	Neutral	0.001
LRP5	O75197-1.2	A1344S	Neutral	0.0
LRP5	O75197-1.2	A1344T	Neutral	0.001
LRP5	O75197-1.2	A1344V	Neutral	0.0
LRP5	O75197-1.2	A1344W	Neutral	0.003
LRP5	O75197-1.2	A1344Y	Neutral	0.003
LRP5	O75197-1.2	S1345A	Neutral	0.0
LRP5	O75197-1.2	S1345C	Neutral	0.001
LRP5	O75197-1.2	S1345D	Neutral	0.0
LRP5	O75197-1.2	S1345E	Neutral	0.0
LRP5	O75197-1.2	S1345F	Neutral	0.001
LRP5	O75197-1.2	S1345G	Neutral	0.0
LRP5	O75197-1.2	S1345H	Neutral	0.001
LRP5	O75197-1.2	S1345I	Neutral	0.001
LRP5	O75197-1.2	S1345K	Neutral	0.0
LRP5	O75197-1.2	S1345L	Neutral	0.001
LRP5	O75197-1.2	S1345M	Neutral	0.0
LRP5	O75197-1.2	S1345N	Neutral	0.0
LRP5	O75197-1.2	S1345P	Neutral	0.001
LRP5	O75197-1.2	S1345Q	Neutral	0.0
LRP5	O75197-1.2	S1345R	Neutral	0.0
LRP5	O75197-1.2	S1345T	Neutral	0.0
LRP5	O75197-1.2	S1345V	Neutral	0.001
LRP5	O75197-1.2	S1345W	Neutral	0.001
LRP5	O75197-1.2	S1345Y	Neutral	0.001
LRP5	O75197-1.2	G1346A	Neutral	0.005
LRP5	O75197-1.2	G1346C	Neutral	0.066
LRP5	O75197-1.2	G1346D	Neutral	0.009
LRP5	O75197-1.2	G1346E	Neutral	0.03
LRP5	O75197-1.2	G1346F	Neutral	0.031
LRP5	O75197-1.2	G1346H	Neutral	0.045
LRP5	O75197-1.2	G1346I	Neutral	0.088
LRP5	O75197-1.2	G1346K	Neutral	0.021
LRP5	O75197-1.2	G1346L	Neutral	0.096
LRP5	O75197-1.2	G1346M	Neutral	0.05
LRP5	O75197-1.2	G1346N	Neutral	0.003
LRP5	O75197-1.2	G1346P	Neutral	0.028
LRP5	O75197-1.2	G1346Q	Neutral	0.042
LRP5	O75197-1.2	G1346R	Neutral	0.02
LRP5	O75197-1.2	G1346S	Neutral	0.006
LRP5	O75197-1.2	G1346T	Neutral	0.042
LRP5	O75197-1.2	G1346V	Neutral	0.053
LRP5	O75197-1.2	G1346W	Neutral	0.007
LRP5	O75197-1.2	G1346Y	Neutral	0.062
LRP5	O75197-1.2	Q1347A	Neutral	0.009
LRP5	O75197-1.2	Q1347C	Neutral	0.045
LRP5	O75197-1.2	Q1347D	Neutral	0.003
LRP5	O75197-1.2	Q1347E	Neutral	0.0
LRP5	O75197-1.2	Q1347F	Neutral	0.023
LRP5	O75197-1.2	Q1347G	Neutral	0.034
LRP5	O75197-1.2	Q1347H	Neutral	0.004
LRP5	O75197-1.2	Q1347I	Neutral	0.023
LRP5	O75197-1.2	Q1347K	Neutral	0.001
LRP5	O75197-1.2	Q1347L	Neutral	0.008
LRP5	O75197-1.2	Q1347M	Neutral	0.001
LRP5	O75197-1.2	Q1347N	Neutral	0.004
LRP5	O75197-1.2	Q1347P	Neutral	0.006
LRP5	O75197-1.2	Q1347R	Neutral	0.001
LRP5	O75197-1.2	Q1347S	Neutral	0.004
LRP5	O75197-1.2	Q1347T	Neutral	0.01
LRP5	O75197-1.2	Q1347V	Neutral	0.013
LRP5	O75197-1.2	Q1347W	Neutral	0.005
LRP5	O75197-1.2	Q1347Y	Neutral	0.005
LRP5	O75197-1.2	C1348A	Pathogenic	0.974
LRP5	O75197-1.2	C1348D	Pathogenic	0.998
LRP5	O75197-1.2	C1348E	Pathogenic	0.999
LRP5	O75197-1.2	C1348F	Pathogenic	0.997
LRP5	O75197-1.2	C1348G	Pathogenic	0.999
LRP5	O75197-1.2	C1348H	Pathogenic	0.999
LRP5	O75197-1.2	C1348I	Pathogenic	0.99
LRP5	O75197-1.2	C1348K	Pathogenic	0.997
LRP5	O75197-1.2	C1348L	Pathogenic	0.991
LRP5	O75197-1.2	C1348M	Pathogenic	0.994
LRP5	O75197-1.2	C1348N	Pathogenic	0.998
LRP5	O75197-1.2	C1348P	Pathogenic	0.999
LRP5	O75197-1.2	C1348Q	Pathogenic	0.998
LRP5	O75197-1.2	C1348R	Pathogenic	0.997
LRP5	O75197-1.2	C1348S	Pathogenic	0.988
LRP5	O75197-1.2	C1348T	Pathogenic	0.991
LRP5	O75197-1.2	C1348V	Pathogenic	0.994
LRP5	O75197-1.2	C1348W	Pathogenic	0.995
LRP5	O75197-1.2	C1348Y	Pathogenic	0.998
LRP5	O75197-1.2	V1349A	Neutral	0.0
LRP5	O75197-1.2	V1349C	Neutral	0.001
LRP5	O75197-1.2	V1349D	Neutral	0.002
LRP5	O75197-1.2	V1349E	Neutral	0.001
LRP5	O75197-1.2	V1349F	Neutral	0.001
LRP5	O75197-1.2	V1349G	Neutral	0.005
LRP5	O75197-1.2	V1349H	Neutral	0.005
LRP5	O75197-1.2	V1349I	Neutral	0.0
LRP5	O75197-1.2	V1349K	Neutral	0.001
LRP5	O75197-1.2	V1349L	Neutral	0.0
LRP5	O75197-1.2	V1349M	Neutral	0.0
LRP5	O75197-1.2	V1349N	Neutral	0.003
LRP5	O75197-1.2	V1349P	Neutral	0.003
LRP5	O75197-1.2	V1349Q	Neutral	0.001
LRP5	O75197-1.2	V1349R	Neutral	0.002
LRP5	O75197-1.2	V1349S	Neutral	0.002
LRP5	O75197-1.2	V1349T	Neutral	0.0
LRP5	O75197-1.2	V1349W	Neutral	0.005
LRP5	O75197-1.2	V1349Y	Neutral	0.001
LRP5	O75197-1.2	L1350A	Neutral	0.0
LRP5	O75197-1.2	L1350C	Neutral	0.0
LRP5	O75197-1.2	L1350D	Neutral	0.001
LRP5	O75197-1.2	L1350E	Neutral	0.0
LRP5	O75197-1.2	L1350F	Neutral	0.0
LRP5	O75197-1.2	L1350G	Neutral	0.001
LRP5	O75197-1.2	L1350H	Neutral	0.0
LRP5	O75197-1.2	L1350I	Neutral	0.0
LRP5	O75197-1.2	L1350K	Neutral	0.0
LRP5	O75197-1.2	L1350M	Neutral	0.0
LRP5	O75197-1.2	L1350N	Neutral	0.0
LRP5	O75197-1.2	L1350P	Neutral	0.001
LRP5	O75197-1.2	L1350Q	Neutral	0.0
LRP5	O75197-1.2	L1350R	Neutral	0.0
LRP5	O75197-1.2	L1350S	Neutral	0.0
LRP5	O75197-1.2	L1350T	Neutral	0.0
LRP5	O75197-1.2	L1350V	Neutral	0.0
LRP5	O75197-1.2	L1350W	Neutral	0.0
LRP5	O75197-1.2	L1350Y	Neutral	0.0
LRP5	O75197-1.2	I1351A	Neutral	0.0
LRP5	O75197-1.2	I1351C	Neutral	0.0
LRP5	O75197-1.2	I1351D	Neutral	0.0
LRP5	O75197-1.2	I1351E	Neutral	0.0
LRP5	O75197-1.2	I1351F	Neutral	0.0
LRP5	O75197-1.2	I1351G	Neutral	0.0
LRP5	O75197-1.2	I1351H	Neutral	0.0
LRP5	O75197-1.2	I1351K	Neutral	0.0
LRP5	O75197-1.2	I1351L	Neutral	0.0
LRP5	O75197-1.2	I1351M	Neutral	0.0
LRP5	O75197-1.2	I1351N	Neutral	0.0
LRP5	O75197-1.2	I1351P	Neutral	0.0
LRP5	O75197-1.2	I1351Q	Neutral	0.0
LRP5	O75197-1.2	I1351R	Neutral	0.0
LRP5	O75197-1.2	I1351S	Neutral	0.0
LRP5	O75197-1.2	I1351T	Neutral	0.0
LRP5	O75197-1.2	I1351V	Neutral	0.0
LRP5	O75197-1.2	I1351W	Neutral	0.0
LRP5	O75197-1.2	I1351Y	Neutral	0.0
LRP5	O75197-1.2	K1352A	Neutral	0.0
LRP5	O75197-1.2	K1352C	Neutral	0.0
LRP5	O75197-1.2	K1352D	Neutral	0.0
LRP5	O75197-1.2	K1352E	Neutral	0.0
LRP5	O75197-1.2	K1352F	Neutral	0.0
LRP5	O75197-1.2	K1352G	Neutral	0.0
LRP5	O75197-1.2	K1352H	Neutral	0.0
LRP5	O75197-1.2	K1352I	Neutral	0.0
LRP5	O75197-1.2	K1352L	Neutral	0.0
LRP5	O75197-1.2	K1352M	Neutral	0.0
LRP5	O75197-1.2	K1352N	Neutral	0.0
LRP5	O75197-1.2	K1352P	Neutral	0.0
LRP5	O75197-1.2	K1352Q	Neutral	0.0
LRP5	O75197-1.2	K1352R	Neutral	0.0
LRP5	O75197-1.2	K1352S	Neutral	0.0
LRP5	O75197-1.2	K1352T	Neutral	0.0
LRP5	O75197-1.2	K1352V	Neutral	0.0
LRP5	O75197-1.2	K1352W	Neutral	0.0
LRP5	O75197-1.2	K1352Y	Neutral	0.0
LRP5	O75197-1.2	Q1353A	Neutral	0.0
LRP5	O75197-1.2	Q1353C	Neutral	0.002
LRP5	O75197-1.2	Q1353D	Neutral	0.0
LRP5	O75197-1.2	Q1353E	Neutral	0.0
LRP5	O75197-1.2	Q1353F	Neutral	0.001
LRP5	O75197-1.2	Q1353G	Neutral	0.001
LRP5	O75197-1.2	Q1353H	Neutral	0.0
LRP5	O75197-1.2	Q1353I	Neutral	0.001
LRP5	O75197-1.2	Q1353K	Neutral	0.0
LRP5	O75197-1.2	Q1353L	Neutral	0.0
LRP5	O75197-1.2	Q1353M	Neutral	0.0
LRP5	O75197-1.2	Q1353N	Neutral	0.0
LRP5	O75197-1.2	Q1353P	Neutral	0.0
LRP5	O75197-1.2	Q1353R	Neutral	0.0
LRP5	O75197-1.2	Q1353S	Neutral	0.0
LRP5	O75197-1.2	Q1353T	Neutral	0.0
LRP5	O75197-1.2	Q1353V	Neutral	0.0
LRP5	O75197-1.2	Q1353W	Neutral	0.0
LRP5	O75197-1.2	Q1353Y	Neutral	0.0
LRP5	O75197-1.2	Q1354A	Neutral	0.001
LRP5	O75197-1.2	Q1354C	Neutral	0.005
LRP5	O75197-1.2	Q1354D	Neutral	0.0
LRP5	O75197-1.2	Q1354E	Neutral	0.0
LRP5	O75197-1.2	Q1354F	Neutral	0.002
LRP5	O75197-1.2	Q1354G	Neutral	0.003
LRP5	O75197-1.2	Q1354H	Neutral	0.0
LRP5	O75197-1.2	Q1354I	Neutral	0.002
LRP5	O75197-1.2	Q1354K	Neutral	0.0
LRP5	O75197-1.2	Q1354L	Neutral	0.001
LRP5	O75197-1.2	Q1354M	Neutral	0.0
LRP5	O75197-1.2	Q1354N	Neutral	0.0
LRP5	O75197-1.2	Q1354P	Neutral	0.001
LRP5	O75197-1.2	Q1354R	Neutral	0.0
LRP5	O75197-1.2	Q1354S	Neutral	0.0
LRP5	O75197-1.2	Q1354T	Neutral	0.001
LRP5	O75197-1.2	Q1354V	Neutral	0.001
LRP5	O75197-1.2	Q1354W	Neutral	0.0
LRP5	O75197-1.2	Q1354Y	Neutral	0.001
LRP5	O75197-1.2	C1355A	Pathogenic	0.992
LRP5	O75197-1.2	C1355D	Pathogenic	0.999
LRP5	O75197-1.2	C1355E	Pathogenic	1.0
LRP5	O75197-1.2	C1355F	Pathogenic	0.999
LRP5	O75197-1.2	C1355G	Pathogenic	1.0
LRP5	O75197-1.2	C1355H	Pathogenic	1.0
LRP5	O75197-1.2	C1355I	Pathogenic	0.997
LRP5	O75197-1.2	C1355K	Pathogenic	0.999
LRP5	O75197-1.2	C1355L	Pathogenic	0.997
LRP5	O75197-1.2	C1355M	Pathogenic	0.998
LRP5	O75197-1.2	C1355N	Pathogenic	0.999
LRP5	O75197-1.2	C1355P	Pathogenic	1.0
LRP5	O75197-1.2	C1355Q	Pathogenic	1.0
LRP5	O75197-1.2	C1355R	Pathogenic	0.999
LRP5	O75197-1.2	C1355S	Pathogenic	0.996
LRP5	O75197-1.2	C1355T	Pathogenic	0.997
LRP5	O75197-1.2	C1355V	Pathogenic	0.998
LRP5	O75197-1.2	C1355W	Pathogenic	0.998
LRP5	O75197-1.2	C1355Y	Pathogenic	0.999
LRP5	O75197-1.2	D1356A	Neutral	0.059
LRP5	O75197-1.2	D1356C	Neutral	0.098
LRP5	O75197-1.2	D1356E	Neutral	0.002
LRP5	O75197-1.2	D1356F	Neutral	0.047
LRP5	O75197-1.2	D1356G	Neutral	0.026
LRP5	O75197-1.2	D1356H	Neutral	0.024
LRP5	O75197-1.2	D1356I	Neutral	0.047
LRP5	O75197-1.2	D1356K	Neutral	0.041
LRP5	O75197-1.2	D1356L	Neutral	0.142
LRP5	O75197-1.2	D1356M	Neutral	0.076
LRP5	O75197-1.2	D1356N	Neutral	0.005
LRP5	O75197-1.2	D1356P	Neutral	0.015
LRP5	O75197-1.2	D1356Q	Neutral	0.011
LRP5	O75197-1.2	D1356R	Neutral	0.113
LRP5	O75197-1.2	D1356S	Neutral	0.009
LRP5	O75197-1.2	D1356T	Neutral	0.022
LRP5	O75197-1.2	D1356V	Neutral	0.08
LRP5	O75197-1.2	D1356W	Neutral	0.087
LRP5	O75197-1.2	D1356Y	Neutral	0.093
LRP5	O75197-1.2	S1357A	Neutral	0.0
LRP5	O75197-1.2	S1357C	Neutral	0.0
LRP5	O75197-1.2	S1357D	Neutral	0.0
LRP5	O75197-1.2	S1357E	Neutral	0.0
LRP5	O75197-1.2	S1357F	Neutral	0.0
LRP5	O75197-1.2	S1357G	Neutral	0.0
LRP5	O75197-1.2	S1357H	Neutral	0.0
LRP5	O75197-1.2	S1357I	Neutral	0.0
LRP5	O75197-1.2	S1357K	Neutral	0.0
LRP5	O75197-1.2	S1357L	Neutral	0.0
LRP5	O75197-1.2	S1357M	Neutral	0.0
LRP5	O75197-1.2	S1357N	Neutral	0.0
LRP5	O75197-1.2	S1357P	Neutral	0.0
LRP5	O75197-1.2	S1357Q	Neutral	0.0
LRP5	O75197-1.2	S1357R	Neutral	0.0
LRP5	O75197-1.2	S1357T	Neutral	0.0
LRP5	O75197-1.2	S1357V	Neutral	0.0
LRP5	O75197-1.2	S1357W	Neutral	0.0
LRP5	O75197-1.2	S1357Y	Neutral	0.0
LRP5	O75197-1.2	F1358A	Neutral	0.0
LRP5	O75197-1.2	F1358C	Neutral	0.001
LRP5	O75197-1.2	F1358D	Neutral	0.0
LRP5	O75197-1.2	F1358E	Neutral	0.0
LRP5	O75197-1.2	F1358G	Neutral	0.001
LRP5	O75197-1.2	F1358H	Neutral	0.0
LRP5	O75197-1.2	F1358I	Neutral	0.0
LRP5	O75197-1.2	F1358K	Neutral	0.0
LRP5	O75197-1.2	F1358L	Neutral	0.0
LRP5	O75197-1.2	F1358M	Neutral	0.0
LRP5	O75197-1.2	F1358N	Neutral	0.0
LRP5	O75197-1.2	F1358P	Neutral	0.005
LRP5	O75197-1.2	F1358Q	Neutral	0.001
LRP5	O75197-1.2	F1358R	Neutral	0.0
LRP5	O75197-1.2	F1358S	Neutral	0.0
LRP5	O75197-1.2	F1358T	Neutral	0.0
LRP5	O75197-1.2	F1358V	Neutral	0.0
LRP5	O75197-1.2	F1358W	Neutral	0.0
LRP5	O75197-1.2	F1358Y	Neutral	0.0
LRP5	O75197-1.2	P1359A	Neutral	0.0
LRP5	O75197-1.2	P1359C	Neutral	0.001
LRP5	O75197-1.2	P1359D	Neutral	0.0
LRP5	O75197-1.2	P1359E	Neutral	0.0
LRP5	O75197-1.2	P1359F	Neutral	0.002
LRP5	O75197-1.2	P1359G	Neutral	0.0
LRP5	O75197-1.2	P1359H	Neutral	0.0
LRP5	O75197-1.2	P1359I	Neutral	0.001
LRP5	O75197-1.2	P1359K	Neutral	0.0
LRP5	O75197-1.2	P1359L	Neutral	0.001
LRP5	O75197-1.2	P1359M	Neutral	0.0
LRP5	O75197-1.2	P1359N	Neutral	0.0
LRP5	O75197-1.2	P1359Q	Neutral	0.0
LRP5	O75197-1.2	P1359R	Neutral	0.0
LRP5	O75197-1.2	P1359S	Neutral	0.0
LRP5	O75197-1.2	P1359T	Neutral	0.0
LRP5	O75197-1.2	P1359V	Neutral	0.0
LRP5	O75197-1.2	P1359W	Neutral	0.001
LRP5	O75197-1.2	P1359Y	Neutral	0.001
LRP5	O75197-1.2	D1360A	Neutral	0.049
LRP5	O75197-1.2	D1360C	Neutral	0.081
LRP5	O75197-1.2	D1360E	Neutral	0.001
LRP5	O75197-1.2	D1360F	Neutral	0.039
LRP5	O75197-1.2	D1360G	Neutral	0.021
LRP5	O75197-1.2	D1360H	Neutral	0.019
LRP5	O75197-1.2	D1360I	Neutral	0.039
LRP5	O75197-1.2	D1360K	Neutral	0.034
LRP5	O75197-1.2	D1360L	Neutral	0.119
LRP5	O75197-1.2	D1360M	Neutral	0.063
LRP5	O75197-1.2	D1360N	Neutral	0.004
LRP5	O75197-1.2	D1360P	Neutral	0.012
LRP5	O75197-1.2	D1360Q	Neutral	0.009
LRP5	O75197-1.2	D1360R	Neutral	0.094
LRP5	O75197-1.2	D1360S	Neutral	0.008
LRP5	O75197-1.2	D1360T	Neutral	0.018
LRP5	O75197-1.2	D1360V	Neutral	0.066
LRP5	O75197-1.2	D1360W	Neutral	0.072
LRP5	O75197-1.2	D1360Y	Neutral	0.077
LRP5	O75197-1.2	C1361A	Pathogenic	0.99
LRP5	O75197-1.2	C1361D	Pathogenic	0.999
LRP5	O75197-1.2	C1361E	Pathogenic	1.0
LRP5	O75197-1.2	C1361F	Pathogenic	0.999
LRP5	O75197-1.2	C1361G	Pathogenic	1.0
LRP5	O75197-1.2	C1361H	Pathogenic	1.0
LRP5	O75197-1.2	C1361I	Pathogenic	0.996
LRP5	O75197-1.2	C1361K	Pathogenic	0.999
LRP5	O75197-1.2	C1361L	Pathogenic	0.996
LRP5	O75197-1.2	C1361M	Pathogenic	0.998
LRP5	O75197-1.2	C1361N	Pathogenic	0.999
LRP5	O75197-1.2	C1361P	Pathogenic	1.0
LRP5	O75197-1.2	C1361Q	Pathogenic	0.999
LRP5	O75197-1.2	C1361R	Pathogenic	0.999
LRP5	O75197-1.2	C1361S	Pathogenic	0.996
LRP5	O75197-1.2	C1361T	Pathogenic	0.997
LRP5	O75197-1.2	C1361V	Pathogenic	0.998
LRP5	O75197-1.2	C1361W	Pathogenic	0.998
LRP5	O75197-1.2	C1361Y	Pathogenic	0.999
LRP5	O75197-1.2	I1362A	Neutral	0.0
LRP5	O75197-1.2	I1362C	Neutral	0.0
LRP5	O75197-1.2	I1362D	Neutral	0.0
LRP5	O75197-1.2	I1362E	Neutral	0.0
LRP5	O75197-1.2	I1362F	Neutral	0.0
LRP5	O75197-1.2	I1362G	Neutral	0.0
LRP5	O75197-1.2	I1362H	Neutral	0.0
LRP5	O75197-1.2	I1362K	Neutral	0.0
LRP5	O75197-1.2	I1362L	Neutral	0.0
LRP5	O75197-1.2	I1362M	Neutral	0.0
LRP5	O75197-1.2	I1362N	Neutral	0.0
LRP5	O75197-1.2	I1362P	Neutral	0.0
LRP5	O75197-1.2	I1362Q	Neutral	0.0
LRP5	O75197-1.2	I1362R	Neutral	0.0
LRP5	O75197-1.2	I1362S	Neutral	0.0
LRP5	O75197-1.2	I1362T	Neutral	0.0
LRP5	O75197-1.2	I1362V	Neutral	0.0
LRP5	O75197-1.2	I1362W	Neutral	0.0
LRP5	O75197-1.2	I1362Y	Neutral	0.0
LRP5	O75197-1.2	D1363A	Neutral	0.101
LRP5	O75197-1.2	D1363C	Neutral	0.162
LRP5	O75197-1.2	D1363E	Neutral	0.003
LRP5	O75197-1.2	D1363F	Neutral	0.081
LRP5	O75197-1.2	D1363G	Neutral	0.045
LRP5	O75197-1.2	D1363H	Neutral	0.041
LRP5	O75197-1.2	D1363I	Neutral	0.081
LRP5	O75197-1.2	D1363K	Neutral	0.072
LRP5	O75197-1.2	D1363L	Neutral	0.228
LRP5	O75197-1.2	D1363M	Neutral	0.129
LRP5	O75197-1.2	D1363N	Neutral	0.009
LRP5	O75197-1.2	D1363P	Neutral	0.026
LRP5	O75197-1.2	D1363Q	Neutral	0.019
LRP5	O75197-1.2	D1363R	Neutral	0.185
LRP5	O75197-1.2	D1363S	Neutral	0.016
LRP5	O75197-1.2	D1363T	Neutral	0.039
LRP5	O75197-1.2	D1363V	Neutral	0.134
LRP5	O75197-1.2	D1363W	Neutral	0.145
LRP5	O75197-1.2	D1363Y	Neutral	0.155
LRP5	O75197-1.2	G1364A	Neutral	0.0
LRP5	O75197-1.2	G1364C	Neutral	0.001
LRP5	O75197-1.2	G1364D	Neutral	0.0
LRP5	O75197-1.2	G1364E	Neutral	0.0
LRP5	O75197-1.2	G1364F	Neutral	0.0
LRP5	O75197-1.2	G1364H	Neutral	0.0
LRP5	O75197-1.2	G1364I	Neutral	0.001
LRP5	O75197-1.2	G1364K	Neutral	0.0
LRP5	O75197-1.2	G1364L	Neutral	0.001
LRP5	O75197-1.2	G1364M	Neutral	0.001
LRP5	O75197-1.2	G1364N	Neutral	0.0
LRP5	O75197-1.2	G1364P	Neutral	0.0
LRP5	O75197-1.2	G1364Q	Neutral	0.0
LRP5	O75197-1.2	G1364R	Neutral	0.0
LRP5	O75197-1.2	G1364S	Neutral	0.0
LRP5	O75197-1.2	G1364T	Neutral	0.0
LRP5	O75197-1.2	G1364V	Neutral	0.001
LRP5	O75197-1.2	G1364W	Neutral	0.0
LRP5	O75197-1.2	G1364Y	Neutral	0.001
LRP5	O75197-1.2	S1365A	Neutral	0.018
LRP5	O75197-1.2	S1365C	Neutral	0.085
LRP5	O75197-1.2	S1365D	Neutral	0.038
LRP5	O75197-1.2	S1365E	Neutral	0.041
LRP5	O75197-1.2	S1365F	Neutral	0.113
LRP5	O75197-1.2	S1365G	Neutral	0.067
LRP5	O75197-1.2	S1365H	Neutral	0.159
LRP5	O75197-1.2	S1365I	Neutral	0.113
LRP5	O75197-1.2	S1365K	Neutral	0.029
LRP5	O75197-1.2	S1365L	Neutral	0.123
LRP5	O75197-1.2	S1365M	Neutral	0.065
LRP5	O75197-1.2	S1365N	Neutral	0.015
LRP5	O75197-1.2	S1365P	Neutral	0.105
LRP5	O75197-1.2	S1365Q	Neutral	0.058
LRP5	O75197-1.2	S1365R	Neutral	0.081
LRP5	O75197-1.2	S1365T	Neutral	0.019
LRP5	O75197-1.2	S1365V	Neutral	0.182
LRP5	O75197-1.2	S1365W	Neutral	0.196
LRP5	O75197-1.2	S1365Y	Neutral	0.209
LRP5	O75197-1.2	D1366A	Neutral	0.065
LRP5	O75197-1.2	D1366C	Neutral	0.106
LRP5	O75197-1.2	D1366E	Neutral	0.002
LRP5	O75197-1.2	D1366F	Neutral	0.052
LRP5	O75197-1.2	D1366G	Neutral	0.028
LRP5	O75197-1.2	D1366H	Neutral	0.026
LRP5	O75197-1.2	D1366I	Neutral	0.052
LRP5	O75197-1.2	D1366K	Neutral	0.045
LRP5	O75197-1.2	D1366L	Neutral	0.154
LRP5	O75197-1.2	D1366M	Neutral	0.083
LRP5	O75197-1.2	D1366N	Neutral	0.006
LRP5	O75197-1.2	D1366P	Neutral	0.016
LRP5	O75197-1.2	D1366Q	Neutral	0.012
LRP5	O75197-1.2	D1366R	Neutral	0.123
LRP5	O75197-1.2	D1366S	Neutral	0.01
LRP5	O75197-1.2	D1366T	Neutral	0.024
LRP5	O75197-1.2	D1366V	Neutral	0.087
LRP5	O75197-1.2	D1366W	Neutral	0.095
LRP5	O75197-1.2	D1366Y	Neutral	0.101
LRP5	O75197-1.2	E1367A	Neutral	0.05
LRP5	O75197-1.2	E1367C	Neutral	0.455
LRP5	O75197-1.2	E1367D	Neutral	0.004
LRP5	O75197-1.2	E1367F	Neutral	0.117
LRP5	O75197-1.2	E1367G	Neutral	0.169
LRP5	O75197-1.2	E1367H	Neutral	0.021
LRP5	O75197-1.2	E1367I	Neutral	0.118
LRP5	O75197-1.2	E1367K	Neutral	0.01
LRP5	O75197-1.2	E1367L	Neutral	0.127
LRP5	O75197-1.2	E1367M	Neutral	0.068
LRP5	O75197-1.2	E1367N	Neutral	0.039
LRP5	O75197-1.2	E1367P	Neutral	0.036
LRP5	O75197-1.2	E1367Q	Neutral	0.003
LRP5	O75197-1.2	E1367R	Neutral	0.028
LRP5	O75197-1.2	E1367S	Neutral	0.023
LRP5	O75197-1.2	E1367T	Neutral	0.054
LRP5	O75197-1.2	E1367V	Neutral	0.07
LRP5	O75197-1.2	E1367W	Neutral	0.077
LRP5	O75197-1.2	E1367Y	Neutral	0.083
LRP5	O75197-1.2	L1368A	Neutral	0.0
LRP5	O75197-1.2	L1368C	Neutral	0.001
LRP5	O75197-1.2	L1368D	Neutral	0.004
LRP5	O75197-1.2	L1368E	Neutral	0.002
LRP5	O75197-1.2	L1368F	Neutral	0.0
LRP5	O75197-1.2	L1368G	Neutral	0.007
LRP5	O75197-1.2	L1368H	Neutral	0.003
LRP5	O75197-1.2	L1368I	Neutral	0.0
LRP5	O75197-1.2	L1368K	Neutral	0.0
LRP5	O75197-1.2	L1368M	Neutral	0.0
LRP5	O75197-1.2	L1368N	Neutral	0.002
LRP5	O75197-1.2	L1368P	Neutral	0.005
LRP5	O75197-1.2	L1368Q	Neutral	0.001
LRP5	O75197-1.2	L1368R	Neutral	0.0
LRP5	O75197-1.2	L1368S	Neutral	0.001
LRP5	O75197-1.2	L1368T	Neutral	0.0
LRP5	O75197-1.2	L1368V	Neutral	0.0
LRP5	O75197-1.2	L1368W	Neutral	0.002
LRP5	O75197-1.2	L1368Y	Neutral	0.001
LRP5	O75197-1.2	M1369A	Neutral	0.0
LRP5	O75197-1.2	M1369C	Neutral	0.0
LRP5	O75197-1.2	M1369D	Neutral	0.0
LRP5	O75197-1.2	M1369E	Neutral	0.0
LRP5	O75197-1.2	M1369F	Neutral	0.0
LRP5	O75197-1.2	M1369G	Neutral	0.0
LRP5	O75197-1.2	M1369H	Neutral	0.0
LRP5	O75197-1.2	M1369I	Neutral	0.0
LRP5	O75197-1.2	M1369K	Neutral	0.0
LRP5	O75197-1.2	M1369L	Neutral	0.0
LRP5	O75197-1.2	M1369N	Neutral	0.0
LRP5	O75197-1.2	M1369P	Neutral	0.0
LRP5	O75197-1.2	M1369Q	Neutral	0.0
LRP5	O75197-1.2	M1369R	Neutral	0.0
LRP5	O75197-1.2	M1369S	Neutral	0.0
LRP5	O75197-1.2	M1369T	Neutral	0.0
LRP5	O75197-1.2	M1369V	Neutral	0.0
LRP5	O75197-1.2	M1369W	Neutral	0.0
LRP5	O75197-1.2	M1369Y	Neutral	0.0
LRP5	O75197-1.2	C1370A	Pathogenic	0.99
LRP5	O75197-1.2	C1370D	Pathogenic	0.999
LRP5	O75197-1.2	C1370E	Pathogenic	1.0
LRP5	O75197-1.2	C1370F	Pathogenic	0.999
LRP5	O75197-1.2	C1370G	Pathogenic	1.0
LRP5	O75197-1.2	C1370H	Pathogenic	1.0
LRP5	O75197-1.2	C1370I	Pathogenic	0.996
LRP5	O75197-1.2	C1370K	Pathogenic	0.999
LRP5	O75197-1.2	C1370L	Pathogenic	0.996
LRP5	O75197-1.2	C1370M	Pathogenic	0.998
LRP5	O75197-1.2	C1370N	Pathogenic	0.999
LRP5	O75197-1.2	C1370P	Pathogenic	1.0
LRP5	O75197-1.2	C1370Q	Pathogenic	0.999
LRP5	O75197-1.2	C1370R	Pathogenic	0.999
LRP5	O75197-1.2	C1370S	Pathogenic	0.995
LRP5	O75197-1.2	C1370T	Pathogenic	0.997
LRP5	O75197-1.2	C1370V	Pathogenic	0.998
LRP5	O75197-1.2	C1370W	Pathogenic	0.998
LRP5	O75197-1.2	C1370Y	Pathogenic	0.999
LRP5	O75197-1.2	E1371A	Neutral	0.0
LRP5	O75197-1.2	E1371C	Neutral	0.003
LRP5	O75197-1.2	E1371D	Neutral	0.0
LRP5	O75197-1.2	E1371F	Neutral	0.0
LRP5	O75197-1.2	E1371G	Neutral	0.001
LRP5	O75197-1.2	E1371H	Neutral	0.0
LRP5	O75197-1.2	E1371I	Neutral	0.0
LRP5	O75197-1.2	E1371K	Neutral	0.0
LRP5	O75197-1.2	E1371L	Neutral	0.0
LRP5	O75197-1.2	E1371M	Neutral	0.0
LRP5	O75197-1.2	E1371N	Neutral	0.0
LRP5	O75197-1.2	E1371P	Neutral	0.0
LRP5	O75197-1.2	E1371Q	Neutral	0.0
LRP5	O75197-1.2	E1371R	Neutral	0.0
LRP5	O75197-1.2	E1371S	Neutral	0.0
LRP5	O75197-1.2	E1371T	Neutral	0.0
LRP5	O75197-1.2	E1371V	Neutral	0.0
LRP5	O75197-1.2	E1371W	Neutral	0.0
LRP5	O75197-1.2	E1371Y	Neutral	0.0
LRP5	O75197-1.2	I1372A	Neutral	0.0
LRP5	O75197-1.2	I1372C	Neutral	0.0
LRP5	O75197-1.2	I1372D	Neutral	0.0
LRP5	O75197-1.2	I1372E	Neutral	0.0
LRP5	O75197-1.2	I1372F	Neutral	0.0
LRP5	O75197-1.2	I1372G	Neutral	0.0
LRP5	O75197-1.2	I1372H	Neutral	0.0
LRP5	O75197-1.2	I1372K	Neutral	0.0
LRP5	O75197-1.2	I1372L	Neutral	0.0
LRP5	O75197-1.2	I1372M	Neutral	0.0
LRP5	O75197-1.2	I1372N	Neutral	0.0
LRP5	O75197-1.2	I1372P	Neutral	0.0
LRP5	O75197-1.2	I1372Q	Neutral	0.0
LRP5	O75197-1.2	I1372R	Neutral	0.0
LRP5	O75197-1.2	I1372S	Neutral	0.0
LRP5	O75197-1.2	I1372T	Neutral	0.0
LRP5	O75197-1.2	I1372V	Neutral	0.0
LRP5	O75197-1.2	I1372W	Neutral	0.0
LRP5	O75197-1.2	I1372Y	Neutral	0.0
LRP5	O75197-1.2	T1373A	Neutral	0.0
LRP5	O75197-1.2	T1373C	Neutral	0.0
LRP5	O75197-1.2	T1373D	Neutral	0.0
LRP5	O75197-1.2	T1373E	Neutral	0.0
LRP5	O75197-1.2	T1373F	Neutral	0.001
LRP5	O75197-1.2	T1373G	Neutral	0.002
LRP5	O75197-1.2	T1373H	Neutral	0.002
LRP5	O75197-1.2	T1373I	Neutral	0.0
LRP5	O75197-1.2	T1373K	Neutral	0.0
LRP5	O75197-1.2	T1373L	Neutral	0.0
LRP5	O75197-1.2	T1373M	Neutral	0.0
LRP5	O75197-1.2	T1373N	Neutral	0.0
LRP5	O75197-1.2	T1373P	Neutral	0.0
LRP5	O75197-1.2	T1373Q	Neutral	0.0
LRP5	O75197-1.2	T1373R	Neutral	0.0
LRP5	O75197-1.2	T1373S	Neutral	0.0
LRP5	O75197-1.2	T1373V	Neutral	0.0
LRP5	O75197-1.2	T1373W	Neutral	0.0
LRP5	O75197-1.2	T1373Y	Neutral	0.001
LRP5	O75197-1.2	K1374A	Neutral	0.0
LRP5	O75197-1.2	K1374C	Neutral	0.0
LRP5	O75197-1.2	K1374D	Neutral	0.0
LRP5	O75197-1.2	K1374E	Neutral	0.0
LRP5	O75197-1.2	K1374F	Neutral	0.0
LRP5	O75197-1.2	K1374G	Neutral	0.0
LRP5	O75197-1.2	K1374H	Neutral	0.0
LRP5	O75197-1.2	K1374I	Neutral	0.0
LRP5	O75197-1.2	K1374L	Neutral	0.0
LRP5	O75197-1.2	K1374M	Neutral	0.0
LRP5	O75197-1.2	K1374N	Neutral	0.0
LRP5	O75197-1.2	K1374P	Neutral	0.0
LRP5	O75197-1.2	K1374Q	Neutral	0.0
LRP5	O75197-1.2	K1374R	Neutral	0.0
LRP5	O75197-1.2	K1374S	Neutral	0.0
LRP5	O75197-1.2	K1374T	Neutral	0.0
LRP5	O75197-1.2	K1374V	Neutral	0.0
LRP5	O75197-1.2	K1374W	Neutral	0.0
LRP5	O75197-1.2	K1374Y	Neutral	0.0
LRP5	O75197-1.2	P1375A	Neutral	0.0
LRP5	O75197-1.2	P1375C	Neutral	0.002
LRP5	O75197-1.2	P1375D	Neutral	0.0
LRP5	O75197-1.2	P1375E	Neutral	0.0
LRP5	O75197-1.2	P1375F	Neutral	0.003
LRP5	O75197-1.2	P1375G	Neutral	0.0
LRP5	O75197-1.2	P1375H	Neutral	0.001
LRP5	O75197-1.2	P1375I	Neutral	0.001
LRP5	O75197-1.2	P1375K	Neutral	0.0
LRP5	O75197-1.2	P1375L	Neutral	0.001
LRP5	O75197-1.2	P1375M	Neutral	0.001
LRP5	O75197-1.2	P1375N	Neutral	0.0
LRP5	O75197-1.2	P1375Q	Neutral	0.0
LRP5	O75197-1.2	P1375R	Neutral	0.0
LRP5	O75197-1.2	P1375S	Neutral	0.0
LRP5	O75197-1.2	P1375T	Neutral	0.0
LRP5	O75197-1.2	P1375V	Neutral	0.001
LRP5	O75197-1.2	P1375W	Neutral	0.002
LRP5	O75197-1.2	P1375Y	Neutral	0.002
LRP5	O75197-1.2	P1376A	Neutral	0.002
LRP5	O75197-1.2	P1376C	Neutral	0.025
LRP5	O75197-1.2	P1376D	Neutral	0.001
LRP5	O75197-1.2	P1376E	Neutral	0.001
LRP5	O75197-1.2	P1376F	Neutral	0.035
LRP5	O75197-1.2	P1376G	Neutral	0.005
LRP5	O75197-1.2	P1376H	Neutral	0.006
LRP5	O75197-1.2	P1376I	Neutral	0.012
LRP5	O75197-1.2	P1376K	Neutral	0.001
LRP5	O75197-1.2	P1376L	Neutral	0.013
LRP5	O75197-1.2	P1376M	Neutral	0.006
LRP5	O75197-1.2	P1376N	Neutral	0.003
LRP5	O75197-1.2	P1376Q	Neutral	0.001
LRP5	O75197-1.2	P1376R	Neutral	0.002
LRP5	O75197-1.2	P1376S	Neutral	0.002
LRP5	O75197-1.2	P1376T	Neutral	0.002
LRP5	O75197-1.2	P1376V	Neutral	0.007
LRP5	O75197-1.2	P1376W	Neutral	0.022
LRP5	O75197-1.2	P1376Y	Neutral	0.024
LRP5	O75197-1.2	S1377A	Neutral	0.0
LRP5	O75197-1.2	S1377C	Neutral	0.0
LRP5	O75197-1.2	S1377D	Neutral	0.0
LRP5	O75197-1.2	S1377E	Neutral	0.0
LRP5	O75197-1.2	S1377F	Neutral	0.0
LRP5	O75197-1.2	S1377G	Neutral	0.0
LRP5	O75197-1.2	S1377H	Neutral	0.0
LRP5	O75197-1.2	S1377I	Neutral	0.0
LRP5	O75197-1.2	S1377K	Neutral	0.0
LRP5	O75197-1.2	S1377L	Neutral	0.0
LRP5	O75197-1.2	S1377M	Neutral	0.0
LRP5	O75197-1.2	S1377N	Neutral	0.0
LRP5	O75197-1.2	S1377P	Neutral	0.0
LRP5	O75197-1.2	S1377Q	Neutral	0.0
LRP5	O75197-1.2	S1377R	Neutral	0.0
LRP5	O75197-1.2	S1377T	Neutral	0.0
LRP5	O75197-1.2	S1377V	Neutral	0.0
LRP5	O75197-1.2	S1377W	Neutral	0.0
LRP5	O75197-1.2	S1377Y	Neutral	0.0
LRP5	O75197-1.2	D1378A	Neutral	0.0
LRP5	O75197-1.2	D1378C	Neutral	0.001
LRP5	O75197-1.2	D1378E	Neutral	0.0
LRP5	O75197-1.2	D1378F	Neutral	0.0
LRP5	O75197-1.2	D1378G	Neutral	0.0
LRP5	O75197-1.2	D1378H	Neutral	0.0
LRP5	O75197-1.2	D1378I	Neutral	0.0
LRP5	O75197-1.2	D1378K	Neutral	0.0
LRP5	O75197-1.2	D1378L	Neutral	0.001
LRP5	O75197-1.2	D1378M	Neutral	0.0
LRP5	O75197-1.2	D1378N	Neutral	0.0
LRP5	O75197-1.2	D1378P	Neutral	0.0
LRP5	O75197-1.2	D1378Q	Neutral	0.0
LRP5	O75197-1.2	D1378R	Neutral	0.001
LRP5	O75197-1.2	D1378S	Neutral	0.0
LRP5	O75197-1.2	D1378T	Neutral	0.0
LRP5	O75197-1.2	D1378V	Neutral	0.0
LRP5	O75197-1.2	D1378W	Neutral	0.0
LRP5	O75197-1.2	D1378Y	Neutral	0.0
LRP5	O75197-1.2	D1379A	Neutral	0.0
LRP5	O75197-1.2	D1379C	Neutral	0.0
LRP5	O75197-1.2	D1379E	Neutral	0.0
LRP5	O75197-1.2	D1379F	Neutral	0.0
LRP5	O75197-1.2	D1379G	Neutral	0.0
LRP5	O75197-1.2	D1379H	Neutral	0.0
LRP5	O75197-1.2	D1379I	Neutral	0.0
LRP5	O75197-1.2	D1379K	Neutral	0.0
LRP5	O75197-1.2	D1379L	Neutral	0.0
LRP5	O75197-1.2	D1379M	Neutral	0.0
LRP5	O75197-1.2	D1379N	Neutral	0.0
LRP5	O75197-1.2	D1379P	Neutral	0.0
LRP5	O75197-1.2	D1379Q	Neutral	0.0
LRP5	O75197-1.2	D1379R	Neutral	0.0
LRP5	O75197-1.2	D1379S	Neutral	0.0
LRP5	O75197-1.2	D1379T	Neutral	0.0
LRP5	O75197-1.2	D1379V	Neutral	0.0
LRP5	O75197-1.2	D1379W	Neutral	0.0
LRP5	O75197-1.2	D1379Y	Neutral	0.0
LRP5	O75197-1.2	S1380A	Neutral	0.0
LRP5	O75197-1.2	S1380C	Neutral	0.0
LRP5	O75197-1.2	S1380D	Neutral	0.0
LRP5	O75197-1.2	S1380E	Neutral	0.0
LRP5	O75197-1.2	S1380F	Neutral	0.0
LRP5	O75197-1.2	S1380G	Neutral	0.0
LRP5	O75197-1.2	S1380H	Neutral	0.0
LRP5	O75197-1.2	S1380I	Neutral	0.0
LRP5	O75197-1.2	S1380K	Neutral	0.0
LRP5	O75197-1.2	S1380L	Neutral	0.0
LRP5	O75197-1.2	S1380M	Neutral	0.0
LRP5	O75197-1.2	S1380N	Neutral	0.0
LRP5	O75197-1.2	S1380P	Neutral	0.0
LRP5	O75197-1.2	S1380Q	Neutral	0.0
LRP5	O75197-1.2	S1380R	Neutral	0.0
LRP5	O75197-1.2	S1380T	Neutral	0.0
LRP5	O75197-1.2	S1380V	Neutral	0.0
LRP5	O75197-1.2	S1380W	Neutral	0.0
LRP5	O75197-1.2	S1380Y	Neutral	0.0
LRP5	O75197-1.2	P1381A	Neutral	0.002
LRP5	O75197-1.2	P1381C	Neutral	0.017
LRP5	O75197-1.2	P1381D	Neutral	0.001
LRP5	O75197-1.2	P1381E	Neutral	0.001
LRP5	O75197-1.2	P1381F	Neutral	0.023
LRP5	O75197-1.2	P1381G	Neutral	0.003
LRP5	O75197-1.2	P1381H	Neutral	0.004
LRP5	O75197-1.2	P1381I	Neutral	0.008
LRP5	O75197-1.2	P1381K	Neutral	0.0
LRP5	O75197-1.2	P1381L	Neutral	0.008
LRP5	O75197-1.2	P1381M	Neutral	0.004
LRP5	O75197-1.2	P1381N	Neutral	0.002
LRP5	O75197-1.2	P1381Q	Neutral	0.001
LRP5	O75197-1.2	P1381R	Neutral	0.001
LRP5	O75197-1.2	P1381S	Neutral	0.001
LRP5	O75197-1.2	P1381T	Neutral	0.002
LRP5	O75197-1.2	P1381V	Neutral	0.004
LRP5	O75197-1.2	P1381W	Neutral	0.015
LRP5	O75197-1.2	P1381Y	Neutral	0.016
LRP5	O75197-1.2	A1382C	Neutral	0.0
LRP5	O75197-1.2	A1382D	Neutral	0.0
LRP5	O75197-1.2	A1382E	Neutral	0.0
LRP5	O75197-1.2	A1382F	Neutral	0.0
LRP5	O75197-1.2	A1382G	Neutral	0.0
LRP5	O75197-1.2	A1382H	Neutral	0.0
LRP5	O75197-1.2	A1382I	Neutral	0.0
LRP5	O75197-1.2	A1382K	Neutral	0.0
LRP5	O75197-1.2	A1382L	Neutral	0.0
LRP5	O75197-1.2	A1382M	Neutral	0.0
LRP5	O75197-1.2	A1382N	Neutral	0.0
LRP5	O75197-1.2	A1382P	Neutral	0.0
LRP5	O75197-1.2	A1382Q	Neutral	0.0
LRP5	O75197-1.2	A1382R	Neutral	0.0
LRP5	O75197-1.2	A1382S	Neutral	0.0
LRP5	O75197-1.2	A1382T	Neutral	0.0
LRP5	O75197-1.2	A1382V	Neutral	0.0
LRP5	O75197-1.2	A1382W	Neutral	0.0
LRP5	O75197-1.2	A1382Y	Neutral	0.0
LRP5	O75197-1.2	H1383A	Neutral	0.0
LRP5	O75197-1.2	H1383C	Neutral	0.0
LRP5	O75197-1.2	H1383D	Neutral	0.0
LRP5	O75197-1.2	H1383E	Neutral	0.0
LRP5	O75197-1.2	H1383F	Neutral	0.0
LRP5	O75197-1.2	H1383G	Neutral	0.0
LRP5	O75197-1.2	H1383I	Neutral	0.0
LRP5	O75197-1.2	H1383K	Neutral	0.0
LRP5	O75197-1.2	H1383L	Neutral	0.0
LRP5	O75197-1.2	H1383M	Neutral	0.0
LRP5	O75197-1.2	H1383N	Neutral	0.0
LRP5	O75197-1.2	H1383P	Neutral	0.0
LRP5	O75197-1.2	H1383Q	Neutral	0.0
LRP5	O75197-1.2	H1383R	Neutral	0.0
LRP5	O75197-1.2	H1383S	Neutral	0.0
LRP5	O75197-1.2	H1383T	Neutral	0.0
LRP5	O75197-1.2	H1383V	Neutral	0.0
LRP5	O75197-1.2	H1383W	Neutral	0.0
LRP5	O75197-1.2	H1383Y	Neutral	0.0
LRP5	O75197-1.2	S1384A	Neutral	0.0
LRP5	O75197-1.2	S1384C	Neutral	0.0
LRP5	O75197-1.2	S1384D	Neutral	0.0
LRP5	O75197-1.2	S1384E	Neutral	0.0
LRP5	O75197-1.2	S1384F	Neutral	0.0
LRP5	O75197-1.2	S1384G	Neutral	0.0
LRP5	O75197-1.2	S1384H	Neutral	0.0
LRP5	O75197-1.2	S1384I	Neutral	0.0
LRP5	O75197-1.2	S1384K	Neutral	0.0
LRP5	O75197-1.2	S1384L	Neutral	0.0
LRP5	O75197-1.2	S1384M	Neutral	0.0
LRP5	O75197-1.2	S1384N	Neutral	0.0
LRP5	O75197-1.2	S1384P	Neutral	0.0
LRP5	O75197-1.2	S1384Q	Neutral	0.0
LRP5	O75197-1.2	S1384R	Neutral	0.0
LRP5	O75197-1.2	S1384T	Neutral	0.0
LRP5	O75197-1.2	S1384V	Neutral	0.0
LRP5	O75197-1.2	S1384W	Neutral	0.0
LRP5	O75197-1.2	S1384Y	Neutral	0.0
LRP5	O75197-1.2	S1385A	Neutral	0.022
LRP5	O75197-1.2	S1385C	Neutral	0.1
LRP5	O75197-1.2	S1385D	Neutral	0.045
LRP5	O75197-1.2	S1385E	Neutral	0.049
LRP5	O75197-1.2	S1385F	Neutral	0.132
LRP5	O75197-1.2	S1385G	Neutral	0.08
LRP5	O75197-1.2	S1385H	Neutral	0.185
LRP5	O75197-1.2	S1385I	Neutral	0.133
LRP5	O75197-1.2	S1385K	Neutral	0.035
LRP5	O75197-1.2	S1385L	Neutral	0.144
LRP5	O75197-1.2	S1385M	Neutral	0.078
LRP5	O75197-1.2	S1385N	Neutral	0.018
LRP5	O75197-1.2	S1385P	Neutral	0.123
LRP5	O75197-1.2	S1385Q	Neutral	0.069
LRP5	O75197-1.2	S1385R	Neutral	0.096
LRP5	O75197-1.2	S1385T	Neutral	0.022
LRP5	O75197-1.2	S1385V	Neutral	0.211
LRP5	O75197-1.2	S1385W	Neutral	0.227
LRP5	O75197-1.2	S1385Y	Neutral	0.241
LRP5	O75197-1.2	A1386C	Neutral	0.024
LRP5	O75197-1.2	A1386D	Neutral	0.136
LRP5	O75197-1.2	A1386E	Neutral	0.053
LRP5	O75197-1.2	A1386F	Neutral	0.093
LRP5	O75197-1.2	A1386G	Neutral	0.033
LRP5	O75197-1.2	A1386H	Neutral	0.252
LRP5	O75197-1.2	A1386I	Neutral	0.033
LRP5	O75197-1.2	A1386K	Neutral	0.038
LRP5	O75197-1.2	A1386L	Neutral	0.036
LRP5	O75197-1.2	A1386M	Neutral	0.053
LRP5	O75197-1.2	A1386N	Neutral	0.153
LRP5	O75197-1.2	A1386P	Neutral	0.086
LRP5	O75197-1.2	A1386Q	Neutral	0.075
LRP5	O75197-1.2	A1386R	Neutral	0.037
LRP5	O75197-1.2	A1386S	Neutral	0.011
LRP5	O75197-1.2	A1386T	Neutral	0.041
LRP5	O75197-1.2	A1386V	Neutral	0.019
LRP5	O75197-1.2	A1386W	Neutral	0.164
LRP5	O75197-1.2	A1386Y	Neutral	0.175
LRP5	O75197-1.2	I1387A	Neutral	0.455
LRP5	O75197-1.2	I1387C	Pathogenic	0.612
LRP5	O75197-1.2	I1387D	Pathogenic	0.754
LRP5	O75197-1.2	I1387E	Pathogenic	0.78
LRP5	O75197-1.2	I1387F	Pathogenic	0.527
LRP5	O75197-1.2	I1387G	Pathogenic	0.945
LRP5	O75197-1.2	I1387H	Pathogenic	0.878
LRP5	O75197-1.2	I1387K	Pathogenic	0.723
LRP5	O75197-1.2	I1387L	Neutral	0.102
LRP5	O75197-1.2	I1387M	Neutral	0.184
LRP5	O75197-1.2	I1387N	Pathogenic	0.782
LRP5	O75197-1.2	I1387P	Pathogenic	0.921
LRP5	O75197-1.2	I1387Q	Pathogenic	0.839
LRP5	O75197-1.2	I1387R	Pathogenic	0.716
LRP5	O75197-1.2	I1387S	Pathogenic	0.654
LRP5	O75197-1.2	I1387T	Neutral	0.454
LRP5	O75197-1.2	I1387V	Neutral	0.023
LRP5	O75197-1.2	I1387W	Pathogenic	0.953
LRP5	O75197-1.2	I1387Y	Pathogenic	0.615
LRP5	O75197-1.2	G1388A	Pathogenic	0.524
LRP5	O75197-1.2	G1388C	Pathogenic	0.943
LRP5	O75197-1.2	G1388D	Pathogenic	0.681
LRP5	O75197-1.2	G1388E	Pathogenic	0.877
LRP5	O75197-1.2	G1388F	Pathogenic	0.881
LRP5	O75197-1.2	G1388H	Pathogenic	0.917
LRP5	O75197-1.2	G1388I	Pathogenic	0.958
LRP5	O75197-1.2	G1388K	Pathogenic	0.833
LRP5	O75197-1.2	G1388L	Pathogenic	0.961
LRP5	O75197-1.2	G1388M	Pathogenic	0.925
LRP5	O75197-1.2	G1388N	Neutral	0.447
LRP5	O75197-1.2	G1388P	Pathogenic	0.872
LRP5	O75197-1.2	G1388Q	Pathogenic	0.911
LRP5	O75197-1.2	G1388R	Pathogenic	0.828
LRP5	O75197-1.2	G1388S	Pathogenic	0.582
LRP5	O75197-1.2	G1388T	Pathogenic	0.911
LRP5	O75197-1.2	G1388V	Pathogenic	0.928
LRP5	O75197-1.2	G1388W	Pathogenic	0.606
LRP5	O75197-1.2	G1388Y	Pathogenic	0.939
LRP5	O75197-1.2	P1389A	Neutral	0.148
LRP5	O75197-1.2	P1389C	Pathogenic	0.654
LRP5	O75197-1.2	P1389D	Neutral	0.064
LRP5	O75197-1.2	P1389E	Neutral	0.07
LRP5	O75197-1.2	P1389F	Pathogenic	0.724
LRP5	O75197-1.2	P1389G	Neutral	0.281
LRP5	O75197-1.2	P1389H	Neutral	0.31
LRP5	O75197-1.2	P1389I	Neutral	0.464
LRP5	O75197-1.2	P1389K	Neutral	0.05
LRP5	O75197-1.2	P1389L	Neutral	0.487
LRP5	O75197-1.2	P1389M	Neutral	0.322
LRP5	O75197-1.2	P1389N	Neutral	0.194
LRP5	O75197-1.2	P1389Q	Neutral	0.098
LRP5	O75197-1.2	P1389R	Neutral	0.134
LRP5	O75197-1.2	P1389S	Neutral	0.114
LRP5	O75197-1.2	P1389T	Neutral	0.147
LRP5	O75197-1.2	P1389V	Neutral	0.331
LRP5	O75197-1.2	P1389W	Pathogenic	0.624
LRP5	O75197-1.2	P1389Y	Pathogenic	0.642
LRP5	O75197-1.2	V1390A	Pathogenic	0.556
LRP5	O75197-1.2	V1390C	Pathogenic	0.878
LRP5	O75197-1.2	V1390D	Pathogenic	0.933
LRP5	O75197-1.2	V1390E	Pathogenic	0.84
LRP5	O75197-1.2	V1390F	Pathogenic	0.839
LRP5	O75197-1.2	V1390G	Pathogenic	0.963
LRP5	O75197-1.2	V1390H	Pathogenic	0.969
LRP5	O75197-1.2	V1390I	Neutral	0.058
LRP5	O75197-1.2	V1390K	Pathogenic	0.786
LRP5	O75197-1.2	V1390L	Neutral	0.383
LRP5	O75197-1.2	V1390M	Neutral	0.486
LRP5	O75197-1.2	V1390N	Pathogenic	0.943
LRP5	O75197-1.2	V1390P	Pathogenic	0.946
LRP5	O75197-1.2	V1390Q	Pathogenic	0.883
LRP5	O75197-1.2	V1390R	Pathogenic	0.915
LRP5	O75197-1.2	V1390S	Pathogenic	0.896
LRP5	O75197-1.2	V1390T	Pathogenic	0.555
LRP5	O75197-1.2	V1390W	Pathogenic	0.968
LRP5	O75197-1.2	V1390Y	Pathogenic	0.873
LRP5	O75197-1.2	I1391A	Pathogenic	0.841
LRP5	O75197-1.2	I1391C	Pathogenic	0.909
LRP5	O75197-1.2	I1391D	Pathogenic	0.951
LRP5	O75197-1.2	I1391E	Pathogenic	0.957
LRP5	O75197-1.2	I1391F	Pathogenic	0.875
LRP5	O75197-1.2	I1391G	Pathogenic	0.991
LRP5	O75197-1.2	I1391H	Pathogenic	0.978
LRP5	O75197-1.2	I1391K	Pathogenic	0.943
LRP5	O75197-1.2	I1391L	Neutral	0.417
LRP5	O75197-1.2	I1391M	Pathogenic	0.588
LRP5	O75197-1.2	I1391N	Pathogenic	0.958
LRP5	O75197-1.2	I1391P	Pathogenic	0.987
LRP5	O75197-1.2	I1391Q	Pathogenic	0.97
LRP5	O75197-1.2	I1391R	Pathogenic	0.941
LRP5	O75197-1.2	I1391S	Pathogenic	0.923
LRP5	O75197-1.2	I1391T	Pathogenic	0.84
LRP5	O75197-1.2	I1391V	Neutral	0.129
LRP5	O75197-1.2	I1391W	Pathogenic	0.992
LRP5	O75197-1.2	I1391Y	Pathogenic	0.91
LRP5	O75197-1.2	G1392A	Neutral	0.434
LRP5	O75197-1.2	G1392C	Pathogenic	0.92
LRP5	O75197-1.2	G1392D	Pathogenic	0.598
LRP5	O75197-1.2	G1392E	Pathogenic	0.832
LRP5	O75197-1.2	G1392F	Pathogenic	0.838
LRP5	O75197-1.2	G1392H	Pathogenic	0.885
LRP5	O75197-1.2	G1392I	Pathogenic	0.94
LRP5	O75197-1.2	G1392K	Pathogenic	0.776
LRP5	O75197-1.2	G1392L	Pathogenic	0.945
LRP5	O75197-1.2	G1392M	Pathogenic	0.896
LRP5	O75197-1.2	G1392N	Neutral	0.361
LRP5	O75197-1.2	G1392P	Pathogenic	0.826
LRP5	O75197-1.2	G1392Q	Pathogenic	0.877
LRP5	O75197-1.2	G1392R	Pathogenic	0.77
LRP5	O75197-1.2	G1392S	Neutral	0.492
LRP5	O75197-1.2	G1392T	Pathogenic	0.877
LRP5	O75197-1.2	G1392V	Pathogenic	0.9
LRP5	O75197-1.2	G1392W	Pathogenic	0.518
LRP5	O75197-1.2	G1392Y	Pathogenic	0.915
LRP5	O75197-1.2	I1393A	Neutral	0.467
LRP5	O75197-1.2	I1393C	Pathogenic	0.623
LRP5	O75197-1.2	I1393D	Pathogenic	0.763
LRP5	O75197-1.2	I1393E	Pathogenic	0.788
LRP5	O75197-1.2	I1393F	Pathogenic	0.538
LRP5	O75197-1.2	I1393G	Pathogenic	0.948
LRP5	O75197-1.2	I1393H	Pathogenic	0.883
LRP5	O75197-1.2	I1393K	Pathogenic	0.732
LRP5	O75197-1.2	I1393L	Neutral	0.106
LRP5	O75197-1.2	I1393M	Neutral	0.191
LRP5	O75197-1.2	I1393N	Pathogenic	0.79
LRP5	O75197-1.2	I1393P	Pathogenic	0.924
LRP5	O75197-1.2	I1393Q	Pathogenic	0.845
LRP5	O75197-1.2	I1393R	Pathogenic	0.725
LRP5	O75197-1.2	I1393S	Pathogenic	0.664
LRP5	O75197-1.2	I1393T	Neutral	0.466
LRP5	O75197-1.2	I1393V	Neutral	0.024
LRP5	O75197-1.2	I1393W	Pathogenic	0.955
LRP5	O75197-1.2	I1393Y	Pathogenic	0.626
LRP5	O75197-1.2	I1394A	Pathogenic	0.649
LRP5	O75197-1.2	I1394C	Pathogenic	0.777
LRP5	O75197-1.2	I1394D	Pathogenic	0.872
LRP5	O75197-1.2	I1394E	Pathogenic	0.887
LRP5	O75197-1.2	I1394F	Pathogenic	0.711
LRP5	O75197-1.2	I1394G	Pathogenic	0.975
LRP5	O75197-1.2	I1394H	Pathogenic	0.941
LRP5	O75197-1.2	I1394K	Pathogenic	0.852
LRP5	O75197-1.2	I1394L	Neutral	0.2
LRP5	O75197-1.2	I1394M	Neutral	0.333
LRP5	O75197-1.2	I1394N	Pathogenic	0.888
LRP5	O75197-1.2	I1394P	Pathogenic	0.962
LRP5	O75197-1.2	I1394Q	Pathogenic	0.92
LRP5	O75197-1.2	I1394R	Pathogenic	0.848
LRP5	O75197-1.2	I1394S	Pathogenic	0.807
LRP5	O75197-1.2	I1394T	Pathogenic	0.648
LRP5	O75197-1.2	I1394V	Neutral	0.049
LRP5	O75197-1.2	I1394W	Pathogenic	0.978
LRP5	O75197-1.2	I1394Y	Pathogenic	0.779
LRP5	O75197-1.2	L1395A	Neutral	0.158
LRP5	O75197-1.2	L1395C	Neutral	0.261
LRP5	O75197-1.2	L1395D	Pathogenic	0.676
LRP5	O75197-1.2	L1395E	Neutral	0.443
LRP5	O75197-1.2	L1395F	Neutral	0.175
LRP5	O75197-1.2	L1395G	Pathogenic	0.795
LRP5	O75197-1.2	L1395H	Pathogenic	0.616
LRP5	O75197-1.2	L1395I	Neutral	0.023
LRP5	O75197-1.2	L1395K	Neutral	0.161
LRP5	O75197-1.2	L1395M	Neutral	0.016
LRP5	O75197-1.2	L1395N	Neutral	0.446
LRP5	O75197-1.2	L1395P	Pathogenic	0.722
LRP5	O75197-1.2	L1395Q	Neutral	0.277
LRP5	O75197-1.2	L1395R	Neutral	0.157
LRP5	O75197-1.2	L1395S	Neutral	0.297
LRP5	O75197-1.2	L1395T	Neutral	0.157
LRP5	O75197-1.2	L1395V	Neutral	0.046
LRP5	O75197-1.2	L1395W	Pathogenic	0.555
LRP5	O75197-1.2	L1395Y	Neutral	0.263
LRP5	O75197-1.2	S1396A	Neutral	0.015
LRP5	O75197-1.2	S1396C	Neutral	0.071
LRP5	O75197-1.2	S1396D	Neutral	0.031
LRP5	O75197-1.2	S1396E	Neutral	0.034
LRP5	O75197-1.2	S1396F	Neutral	0.095
LRP5	O75197-1.2	S1396G	Neutral	0.056
LRP5	O75197-1.2	S1396H	Neutral	0.135
LRP5	O75197-1.2	S1396I	Neutral	0.095
LRP5	O75197-1.2	S1396K	Neutral	0.024
LRP5	O75197-1.2	S1396L	Neutral	0.104
LRP5	O75197-1.2	S1396M	Neutral	0.055
LRP5	O75197-1.2	S1396N	Neutral	0.012
LRP5	O75197-1.2	S1396P	Neutral	0.088
LRP5	O75197-1.2	S1396Q	Neutral	0.048
LRP5	O75197-1.2	S1396R	Neutral	0.068
LRP5	O75197-1.2	S1396T	Neutral	0.015
LRP5	O75197-1.2	S1396V	Neutral	0.155
LRP5	O75197-1.2	S1396W	Neutral	0.168
LRP5	O75197-1.2	S1396Y	Neutral	0.179
LRP5	O75197-1.2	L1397A	Neutral	0.18
LRP5	O75197-1.2	L1397C	Neutral	0.292
LRP5	O75197-1.2	L1397D	Pathogenic	0.71
LRP5	O75197-1.2	L1397E	Neutral	0.482
LRP5	O75197-1.2	L1397F	Neutral	0.199
LRP5	O75197-1.2	L1397G	Pathogenic	0.82
LRP5	O75197-1.2	L1397H	Pathogenic	0.653
LRP5	O75197-1.2	L1397I	Neutral	0.026
LRP5	O75197-1.2	L1397K	Neutral	0.184
LRP5	O75197-1.2	L1397M	Neutral	0.019
LRP5	O75197-1.2	L1397N	Neutral	0.485
LRP5	O75197-1.2	L1397P	Pathogenic	0.752
LRP5	O75197-1.2	L1397Q	Neutral	0.31
LRP5	O75197-1.2	L1397R	Neutral	0.179
LRP5	O75197-1.2	L1397S	Neutral	0.331
LRP5	O75197-1.2	L1397T	Neutral	0.179
LRP5	O75197-1.2	L1397V	Neutral	0.054
LRP5	O75197-1.2	L1397W	Pathogenic	0.593
LRP5	O75197-1.2	L1397Y	Neutral	0.295
LRP5	O75197-1.2	F1398A	Pathogenic	0.979
LRP5	O75197-1.2	F1398C	Pathogenic	0.989
LRP5	O75197-1.2	F1398D	Pathogenic	0.983
LRP5	O75197-1.2	F1398E	Pathogenic	0.985
LRP5	O75197-1.2	F1398G	Pathogenic	0.991
LRP5	O75197-1.2	F1398H	Pathogenic	0.934
LRP5	O75197-1.2	F1398I	Pathogenic	0.953
LRP5	O75197-1.2	F1398K	Pathogenic	0.98
LRP5	O75197-1.2	F1398L	Pathogenic	0.95
LRP5	O75197-1.2	F1398M	Pathogenic	0.926
LRP5	O75197-1.2	F1398N	Pathogenic	0.985
LRP5	O75197-1.2	F1398P	Pathogenic	0.998
LRP5	O75197-1.2	F1398Q	Pathogenic	0.99
LRP5	O75197-1.2	F1398R	Pathogenic	0.98
LRP5	O75197-1.2	F1398S	Pathogenic	0.972
LRP5	O75197-1.2	F1398T	Pathogenic	0.979
LRP5	O75197-1.2	F1398V	Pathogenic	0.973
LRP5	O75197-1.2	F1398W	Pathogenic	0.814
LRP5	O75197-1.2	F1398Y	Neutral	0.261
LRP5	O75197-1.2	V1399A	Neutral	0.47
LRP5	O75197-1.2	V1399C	Pathogenic	0.836
LRP5	O75197-1.2	V1399D	Pathogenic	0.908
LRP5	O75197-1.2	V1399E	Pathogenic	0.788
LRP5	O75197-1.2	V1399F	Pathogenic	0.787
LRP5	O75197-1.2	V1399G	Pathogenic	0.949
LRP5	O75197-1.2	V1399H	Pathogenic	0.957
LRP5	O75197-1.2	V1399I	Neutral	0.042
LRP5	O75197-1.2	V1399K	Pathogenic	0.723
LRP5	O75197-1.2	V1399L	Neutral	0.306
LRP5	O75197-1.2	V1399M	Neutral	0.401
LRP5	O75197-1.2	V1399N	Pathogenic	0.921
LRP5	O75197-1.2	V1399P	Pathogenic	0.925
LRP5	O75197-1.2	V1399Q	Pathogenic	0.843
LRP5	O75197-1.2	V1399R	Pathogenic	0.885
LRP5	O75197-1.2	V1399S	Pathogenic	0.859
LRP5	O75197-1.2	V1399T	Neutral	0.469
LRP5	O75197-1.2	V1399W	Pathogenic	0.956
LRP5	O75197-1.2	V1399Y	Pathogenic	0.829
LRP5	O75197-1.2	M1400A	Neutral	0.156
LRP5	O75197-1.2	M1400C	Neutral	0.258
LRP5	O75197-1.2	M1400D	Neutral	0.404
LRP5	O75197-1.2	M1400E	Neutral	0.205
LRP5	O75197-1.2	M1400F	Neutral	0.083
LRP5	O75197-1.2	M1400G	Pathogenic	0.558
LRP5	O75197-1.2	M1400H	Neutral	0.343
LRP5	O75197-1.2	M1400I	Neutral	0.029
LRP5	O75197-1.2	M1400K	Neutral	0.059
LRP5	O75197-1.2	M1400L	Neutral	0.011
LRP5	O75197-1.2	M1400N	Neutral	0.207
LRP5	O75197-1.2	M1400P	Neutral	0.457
LRP5	O75197-1.2	M1400Q	Neutral	0.039
LRP5	O75197-1.2	M1400R	Neutral	0.057
LRP5	O75197-1.2	M1400S	Neutral	0.121
LRP5	O75197-1.2	M1400T	Neutral	0.156
LRP5	O75197-1.2	M1400V	Neutral	0.046
LRP5	O75197-1.2	M1400W	Neutral	0.149
LRP5	O75197-1.2	M1400Y	Neutral	0.261
LRP5	O75197-1.2	G1401A	Pathogenic	0.887
LRP5	O75197-1.2	G1401C	Pathogenic	0.992
LRP5	O75197-1.2	G1401D	Pathogenic	0.938
LRP5	O75197-1.2	G1401E	Pathogenic	0.981
LRP5	O75197-1.2	G1401F	Pathogenic	0.981
LRP5	O75197-1.2	G1401H	Pathogenic	0.987
LRP5	O75197-1.2	G1401I	Pathogenic	0.994
LRP5	O75197-1.2	G1401K	Pathogenic	0.973
LRP5	O75197-1.2	G1401L	Pathogenic	0.994
LRP5	O75197-1.2	G1401M	Pathogenic	0.989
LRP5	O75197-1.2	G1401N	Pathogenic	0.852
LRP5	O75197-1.2	G1401P	Pathogenic	0.98
LRP5	O75197-1.2	G1401Q	Pathogenic	0.986
LRP5	O75197-1.2	G1401R	Pathogenic	0.972
LRP5	O75197-1.2	G1401S	Pathogenic	0.908
LRP5	O75197-1.2	G1401T	Pathogenic	0.986
LRP5	O75197-1.2	G1401V	Pathogenic	0.989
LRP5	O75197-1.2	G1401W	Pathogenic	0.916
LRP5	O75197-1.2	G1401Y	Pathogenic	0.991
LRP5	O75197-1.2	G1402A	Neutral	0.033
LRP5	O75197-1.2	G1402C	Neutral	0.34
LRP5	O75197-1.2	G1402D	Neutral	0.063
LRP5	O75197-1.2	G1402E	Neutral	0.182
LRP5	O75197-1.2	G1402F	Neutral	0.188
LRP5	O75197-1.2	G1402H	Neutral	0.256
LRP5	O75197-1.2	G1402I	Neutral	0.414
LRP5	O75197-1.2	G1402K	Neutral	0.134
LRP5	O75197-1.2	G1402L	Neutral	0.437
LRP5	O75197-1.2	G1402M	Neutral	0.279
LRP5	O75197-1.2	G1402N	Neutral	0.025
LRP5	O75197-1.2	G1402P	Neutral	0.175
LRP5	O75197-1.2	G1402Q	Neutral	0.242
LRP5	O75197-1.2	G1402R	Neutral	0.131
LRP5	O75197-1.2	G1402S	Neutral	0.042
LRP5	O75197-1.2	G1402T	Neutral	0.242
LRP5	O75197-1.2	G1402V	Neutral	0.288
LRP5	O75197-1.2	G1402W	Neutral	0.046
LRP5	O75197-1.2	G1402Y	Neutral	0.325
LRP5	O75197-1.2	V1403A	Neutral	0.009
LRP5	O75197-1.2	V1403C	Neutral	0.051
LRP5	O75197-1.2	V1403D	Neutral	0.095
LRP5	O75197-1.2	V1403E	Neutral	0.038
LRP5	O75197-1.2	V1403F	Neutral	0.038
LRP5	O75197-1.2	V1403G	Neutral	0.163
LRP5	O75197-1.2	V1403H	Neutral	0.19
LRP5	O75197-1.2	V1403I	Neutral	0.0
LRP5	O75197-1.2	V1403K	Neutral	0.027
LRP5	O75197-1.2	V1403L	Neutral	0.005
LRP5	O75197-1.2	V1403M	Neutral	0.007
LRP5	O75197-1.2	V1403N	Neutral	0.109
LRP5	O75197-1.2	V1403P	Neutral	0.115
LRP5	O75197-1.2	V1403Q	Neutral	0.054
LRP5	O75197-1.2	V1403R	Neutral	0.075
LRP5	O75197-1.2	V1403S	Neutral	0.06
LRP5	O75197-1.2	V1403T	Neutral	0.009
LRP5	O75197-1.2	V1403W	Neutral	0.186
LRP5	O75197-1.2	V1403Y	Neutral	0.049
LRP5	O75197-1.2	Y1404A	Pathogenic	0.984
LRP5	O75197-1.2	Y1404C	Pathogenic	0.991
LRP5	O75197-1.2	Y1404D	Pathogenic	0.987
LRP5	O75197-1.2	Y1404E	Pathogenic	0.966
LRP5	O75197-1.2	Y1404F	Neutral	0.182
LRP5	O75197-1.2	Y1404G	Pathogenic	0.993
LRP5	O75197-1.2	Y1404H	Neutral	0.398
LRP5	O75197-1.2	Y1404I	Pathogenic	0.949
LRP5	O75197-1.2	Y1404K	Pathogenic	0.955
LRP5	O75197-1.2	Y1404L	Pathogenic	0.953
LRP5	O75197-1.2	Y1404M	Pathogenic	0.969
LRP5	O75197-1.2	Y1404N	Pathogenic	0.966
LRP5	O75197-1.2	Y1404P	Pathogenic	0.996
LRP5	O75197-1.2	Y1404Q	Pathogenic	0.931
LRP5	O75197-1.2	Y1404R	Pathogenic	0.955
LRP5	O75197-1.2	Y1404S	Pathogenic	0.978
LRP5	O75197-1.2	Y1404T	Pathogenic	0.984
LRP5	O75197-1.2	Y1404V	Pathogenic	0.968
LRP5	O75197-1.2	Y1404W	Neutral	0.304
LRP5	O75197-1.2	F1405A	Pathogenic	0.979
LRP5	O75197-1.2	F1405C	Pathogenic	0.989
LRP5	O75197-1.2	F1405D	Pathogenic	0.983
LRP5	O75197-1.2	F1405E	Pathogenic	0.985
LRP5	O75197-1.2	F1405G	Pathogenic	0.991
LRP5	O75197-1.2	F1405H	Pathogenic	0.936
LRP5	O75197-1.2	F1405I	Pathogenic	0.954
LRP5	O75197-1.2	F1405K	Pathogenic	0.981
LRP5	O75197-1.2	F1405L	Pathogenic	0.951
LRP5	O75197-1.2	F1405M	Pathogenic	0.928
LRP5	O75197-1.2	F1405N	Pathogenic	0.985
LRP5	O75197-1.2	F1405P	Pathogenic	0.998
LRP5	O75197-1.2	F1405Q	Pathogenic	0.99
LRP5	O75197-1.2	F1405R	Pathogenic	0.98
LRP5	O75197-1.2	F1405S	Pathogenic	0.972
LRP5	O75197-1.2	F1405T	Pathogenic	0.979
LRP5	O75197-1.2	F1405V	Pathogenic	0.974
LRP5	O75197-1.2	F1405W	Pathogenic	0.818
LRP5	O75197-1.2	F1405Y	Neutral	0.266
LRP5	O75197-1.2	V1406A	Neutral	0.126
LRP5	O75197-1.2	V1406C	Neutral	0.453
LRP5	O75197-1.2	V1406D	Pathogenic	0.617
LRP5	O75197-1.2	V1406E	Neutral	0.377
LRP5	O75197-1.2	V1406F	Neutral	0.375
LRP5	O75197-1.2	V1406G	Pathogenic	0.749
LRP5	O75197-1.2	V1406H	Pathogenic	0.783
LRP5	O75197-1.2	V1406I	Neutral	0.007
LRP5	O75197-1.2	V1406K	Neutral	0.298
LRP5	O75197-1.2	V1406L	Neutral	0.067
LRP5	O75197-1.2	V1406M	Neutral	0.098
LRP5	O75197-1.2	V1406N	Pathogenic	0.654
LRP5	O75197-1.2	V1406P	Pathogenic	0.667
LRP5	O75197-1.2	V1406Q	Neutral	0.466
LRP5	O75197-1.2	V1406R	Pathogenic	0.555
LRP5	O75197-1.2	V1406S	Neutral	0.497
LRP5	O75197-1.2	V1406T	Neutral	0.126
LRP5	O75197-1.2	V1406W	Pathogenic	0.779
LRP5	O75197-1.2	V1406Y	Neutral	0.441
LRP5	O75197-1.2	C1407A	Pathogenic	0.964
LRP5	O75197-1.2	C1407D	Pathogenic	0.997
LRP5	O75197-1.2	C1407E	Pathogenic	0.999
LRP5	O75197-1.2	C1407F	Pathogenic	0.995
LRP5	O75197-1.2	C1407G	Pathogenic	0.998
LRP5	O75197-1.2	C1407H	Pathogenic	0.998
LRP5	O75197-1.2	C1407I	Pathogenic	0.986
LRP5	O75197-1.2	C1407K	Pathogenic	0.996
LRP5	O75197-1.2	C1407L	Pathogenic	0.987
LRP5	O75197-1.2	C1407M	Pathogenic	0.991
LRP5	O75197-1.2	C1407N	Pathogenic	0.997
LRP5	O75197-1.2	C1407P	Pathogenic	0.999
LRP5	O75197-1.2	C1407Q	Pathogenic	0.998
LRP5	O75197-1.2	C1407R	Pathogenic	0.995
LRP5	O75197-1.2	C1407S	Pathogenic	0.984
LRP5	O75197-1.2	C1407T	Pathogenic	0.988
LRP5	O75197-1.2	C1407V	Pathogenic	0.992
LRP5	O75197-1.2	C1407W	Pathogenic	0.992
LRP5	O75197-1.2	C1407Y	Pathogenic	0.998
LRP5	O75197-1.2	Q1408A	Neutral	0.012
LRP5	O75197-1.2	Q1408C	Neutral	0.062
LRP5	O75197-1.2	Q1408D	Neutral	0.004
LRP5	O75197-1.2	Q1408E	Neutral	0.001
LRP5	O75197-1.2	Q1408F	Neutral	0.031
LRP5	O75197-1.2	Q1408G	Neutral	0.047
LRP5	O75197-1.2	Q1408H	Neutral	0.005
LRP5	O75197-1.2	Q1408I	Neutral	0.032
LRP5	O75197-1.2	Q1408K	Neutral	0.001
LRP5	O75197-1.2	Q1408L	Neutral	0.012
LRP5	O75197-1.2	Q1408M	Neutral	0.002
LRP5	O75197-1.2	Q1408N	Neutral	0.005
LRP5	O75197-1.2	Q1408P	Neutral	0.009
LRP5	O75197-1.2	Q1408R	Neutral	0.001
LRP5	O75197-1.2	Q1408S	Neutral	0.006
LRP5	O75197-1.2	Q1408T	Neutral	0.014
LRP5	O75197-1.2	Q1408V	Neutral	0.018
LRP5	O75197-1.2	Q1408W	Neutral	0.007
LRP5	O75197-1.2	Q1408Y	Neutral	0.007
LRP5	O75197-1.2	R1409A	Neutral	0.007
LRP5	O75197-1.2	R1409C	Neutral	0.037
LRP5	O75197-1.2	R1409D	Neutral	0.057
LRP5	O75197-1.2	R1409E	Neutral	0.006
LRP5	O75197-1.2	R1409F	Neutral	0.02
LRP5	O75197-1.2	R1409G	Neutral	0.028
LRP5	O75197-1.2	R1409H	Neutral	0.003
LRP5	O75197-1.2	R1409I	Neutral	0.019
LRP5	O75197-1.2	R1409K	Neutral	0.001
LRP5	O75197-1.2	R1409L	Neutral	0.007
LRP5	O75197-1.2	R1409M	Neutral	0.003
LRP5	O75197-1.2	R1409N	Neutral	0.006
LRP5	O75197-1.2	R1409P	Neutral	0.016
LRP5	O75197-1.2	R1409Q	Neutral	0.001
LRP5	O75197-1.2	R1409S	Neutral	0.01
LRP5	O75197-1.2	R1409T	Neutral	0.008
LRP5	O75197-1.2	R1409V	Neutral	0.031
LRP5	O75197-1.2	R1409W	Neutral	0.013
LRP5	O75197-1.2	R1409Y	Neutral	0.014
LRP5	O75197-1.2	V1410A	Neutral	0.0
LRP5	O75197-1.2	V1410C	Neutral	0.002
LRP5	O75197-1.2	V1410D	Neutral	0.004
LRP5	O75197-1.2	V1410E	Neutral	0.001
LRP5	O75197-1.2	V1410F	Neutral	0.001
LRP5	O75197-1.2	V1410G	Neutral	0.007
LRP5	O75197-1.2	V1410H	Neutral	0.008
LRP5	O75197-1.2	V1410I	Neutral	0.0
LRP5	O75197-1.2	V1410K	Neutral	0.001
LRP5	O75197-1.2	V1410L	Neutral	0.0
LRP5	O75197-1.2	V1410M	Neutral	0.0
LRP5	O75197-1.2	V1410N	Neutral	0.004
LRP5	O75197-1.2	V1410P	Neutral	0.005
LRP5	O75197-1.2	V1410Q	Neutral	0.002
LRP5	O75197-1.2	V1410R	Neutral	0.003
LRP5	O75197-1.2	V1410S	Neutral	0.002
LRP5	O75197-1.2	V1410T	Neutral	0.0
LRP5	O75197-1.2	V1410W	Neutral	0.008
LRP5	O75197-1.2	V1410Y	Neutral	0.002
LRP5	O75197-1.2	V1411A	Neutral	0.0
LRP5	O75197-1.2	V1411C	Neutral	0.0
LRP5	O75197-1.2	V1411D	Neutral	0.0
LRP5	O75197-1.2	V1411E	Neutral	0.0
LRP5	O75197-1.2	V1411F	Neutral	0.0
LRP5	O75197-1.2	V1411G	Neutral	0.001
LRP5	O75197-1.2	V1411H	Neutral	0.001
LRP5	O75197-1.2	V1411I	Neutral	0.0
LRP5	O75197-1.2	V1411K	Neutral	0.0
LRP5	O75197-1.2	V1411L	Neutral	0.0
LRP5	O75197-1.2	V1411M	Neutral	0.0
LRP5	O75197-1.2	V1411N	Neutral	0.0
LRP5	O75197-1.2	V1411P	Neutral	0.0
LRP5	O75197-1.2	V1411Q	Neutral	0.0
LRP5	O75197-1.2	V1411R	Neutral	0.0
LRP5	O75197-1.2	V1411S	Neutral	0.0
LRP5	O75197-1.2	V1411T	Neutral	0.0
LRP5	O75197-1.2	V1411W	Neutral	0.001
LRP5	O75197-1.2	V1411Y	Neutral	0.0
LRP5	O75197-1.2	C1412A	Neutral	0.005
LRP5	O75197-1.2	C1412D	Neutral	0.048
LRP5	O75197-1.2	C1412E	Neutral	0.143
LRP5	O75197-1.2	C1412F	Neutral	0.035
LRP5	O75197-1.2	C1412G	Neutral	0.087
LRP5	O75197-1.2	C1412H	Neutral	0.097
LRP5	O75197-1.2	C1412I	Neutral	0.012
LRP5	O75197-1.2	C1412K	Neutral	0.037
LRP5	O75197-1.2	C1412L	Neutral	0.013
LRP5	O75197-1.2	C1412M	Neutral	0.019
LRP5	O75197-1.2	C1412N	Neutral	0.055
LRP5	O75197-1.2	C1412P	Neutral	0.16
LRP5	O75197-1.2	C1412Q	Neutral	0.074
LRP5	O75197-1.2	C1412R	Neutral	0.036
LRP5	O75197-1.2	C1412S	Neutral	0.01
LRP5	O75197-1.2	C1412T	Neutral	0.013
LRP5	O75197-1.2	C1412V	Neutral	0.02
LRP5	O75197-1.2	C1412W	Neutral	0.022
LRP5	O75197-1.2	C1412Y	Neutral	0.067
LRP5	O75197-1.2	Q1413A	Neutral	0.0
LRP5	O75197-1.2	Q1413C	Neutral	0.002
LRP5	O75197-1.2	Q1413D	Neutral	0.0
LRP5	O75197-1.2	Q1413E	Neutral	0.0
LRP5	O75197-1.2	Q1413F	Neutral	0.001
LRP5	O75197-1.2	Q1413G	Neutral	0.001
LRP5	O75197-1.2	Q1413H	Neutral	0.0
LRP5	O75197-1.2	Q1413I	Neutral	0.001
LRP5	O75197-1.2	Q1413K	Neutral	0.0
LRP5	O75197-1.2	Q1413L	Neutral	0.0
LRP5	O75197-1.2	Q1413M	Neutral	0.0
LRP5	O75197-1.2	Q1413N	Neutral	0.0
LRP5	O75197-1.2	Q1413P	Neutral	0.0
LRP5	O75197-1.2	Q1413R	Neutral	0.0
LRP5	O75197-1.2	Q1413S	Neutral	0.0
LRP5	O75197-1.2	Q1413T	Neutral	0.0
LRP5	O75197-1.2	Q1413V	Neutral	0.0
LRP5	O75197-1.2	Q1413W	Neutral	0.0
LRP5	O75197-1.2	Q1413Y	Neutral	0.0
LRP5	O75197-1.2	R1414A	Neutral	0.001
LRP5	O75197-1.2	R1414C	Neutral	0.004
LRP5	O75197-1.2	R1414D	Neutral	0.007
LRP5	O75197-1.2	R1414E	Neutral	0.001
LRP5	O75197-1.2	R1414F	Neutral	0.002
LRP5	O75197-1.2	R1414G	Neutral	0.003
LRP5	O75197-1.2	R1414H	Neutral	0.0
LRP5	O75197-1.2	R1414I	Neutral	0.002
LRP5	O75197-1.2	R1414K	Neutral	0.0
LRP5	O75197-1.2	R1414L	Neutral	0.001
LRP5	O75197-1.2	R1414M	Neutral	0.0
LRP5	O75197-1.2	R1414N	Neutral	0.001
LRP5	O75197-1.2	R1414P	Neutral	0.002
LRP5	O75197-1.2	R1414Q	Neutral	0.0
LRP5	O75197-1.2	R1414S	Neutral	0.001
LRP5	O75197-1.2	R1414T	Neutral	0.001
LRP5	O75197-1.2	R1414V	Neutral	0.004
LRP5	O75197-1.2	R1414W	Neutral	0.002
LRP5	O75197-1.2	R1414Y	Neutral	0.002
LRP5	O75197-1.2	Y1415A	Neutral	0.001
LRP5	O75197-1.2	Y1415C	Neutral	0.002
LRP5	O75197-1.2	Y1415D	Neutral	0.001
LRP5	O75197-1.2	Y1415E	Neutral	0.001
LRP5	O75197-1.2	Y1415F	Neutral	0.0
LRP5	O75197-1.2	Y1415G	Neutral	0.003
LRP5	O75197-1.2	Y1415H	Neutral	0.0
LRP5	O75197-1.2	Y1415I	Neutral	0.0
LRP5	O75197-1.2	Y1415K	Neutral	0.0
LRP5	O75197-1.2	Y1415L	Neutral	0.0
LRP5	O75197-1.2	Y1415M	Neutral	0.001
LRP5	O75197-1.2	Y1415N	Neutral	0.001
LRP5	O75197-1.2	Y1415P	Neutral	0.005
LRP5	O75197-1.2	Y1415Q	Neutral	0.0
LRP5	O75197-1.2	Y1415R	Neutral	0.0
LRP5	O75197-1.2	Y1415S	Neutral	0.001
LRP5	O75197-1.2	Y1415T	Neutral	0.001
LRP5	O75197-1.2	Y1415V	Neutral	0.001
LRP5	O75197-1.2	Y1415W	Neutral	0.0
LRP5	O75197-1.2	A1416C	Neutral	0.0
LRP5	O75197-1.2	A1416D	Neutral	0.0
LRP5	O75197-1.2	A1416E	Neutral	0.0
LRP5	O75197-1.2	A1416F	Neutral	0.0
LRP5	O75197-1.2	A1416G	Neutral	0.0
LRP5	O75197-1.2	A1416H	Neutral	0.0
LRP5	O75197-1.2	A1416I	Neutral	0.0
LRP5	O75197-1.2	A1416K	Neutral	0.0
LRP5	O75197-1.2	A1416L	Neutral	0.0
LRP5	O75197-1.2	A1416M	Neutral	0.0
LRP5	O75197-1.2	A1416N	Neutral	0.0
LRP5	O75197-1.2	A1416P	Neutral	0.0
LRP5	O75197-1.2	A1416Q	Neutral	0.0
LRP5	O75197-1.2	A1416R	Neutral	0.0
LRP5	O75197-1.2	A1416S	Neutral	0.0
LRP5	O75197-1.2	A1416T	Neutral	0.0
LRP5	O75197-1.2	A1416V	Neutral	0.0
LRP5	O75197-1.2	A1416W	Neutral	0.0
LRP5	O75197-1.2	A1416Y	Neutral	0.0
LRP5	O75197-1.2	G1417A	Neutral	0.001
LRP5	O75197-1.2	G1417C	Neutral	0.007
LRP5	O75197-1.2	G1417D	Neutral	0.001
LRP5	O75197-1.2	G1417E	Neutral	0.003
LRP5	O75197-1.2	G1417F	Neutral	0.003
LRP5	O75197-1.2	G1417H	Neutral	0.005
LRP5	O75197-1.2	G1417I	Neutral	0.01
LRP5	O75197-1.2	G1417K	Neutral	0.002
LRP5	O75197-1.2	G1417L	Neutral	0.011
LRP5	O75197-1.2	G1417M	Neutral	0.006
LRP5	O75197-1.2	G1417N	Neutral	0.0
LRP5	O75197-1.2	G1417P	Neutral	0.003
LRP5	O75197-1.2	G1417Q	Neutral	0.005
LRP5	O75197-1.2	G1417R	Neutral	0.002
LRP5	O75197-1.2	G1417S	Neutral	0.001
LRP5	O75197-1.2	G1417T	Neutral	0.005
LRP5	O75197-1.2	G1417V	Neutral	0.006
LRP5	O75197-1.2	G1417W	Neutral	0.001
LRP5	O75197-1.2	G1417Y	Neutral	0.007
LRP5	O75197-1.2	A1418C	Neutral	0.0
LRP5	O75197-1.2	A1418D	Neutral	0.0
LRP5	O75197-1.2	A1418E	Neutral	0.0
LRP5	O75197-1.2	A1418F	Neutral	0.0
LRP5	O75197-1.2	A1418G	Neutral	0.0
LRP5	O75197-1.2	A1418H	Neutral	0.001
LRP5	O75197-1.2	A1418I	Neutral	0.0
LRP5	O75197-1.2	A1418K	Neutral	0.0
LRP5	O75197-1.2	A1418L	Neutral	0.0
LRP5	O75197-1.2	A1418M	Neutral	0.0
LRP5	O75197-1.2	A1418N	Neutral	0.0
LRP5	O75197-1.2	A1418P	Neutral	0.0
LRP5	O75197-1.2	A1418Q	Neutral	0.0
LRP5	O75197-1.2	A1418R	Neutral	0.0
LRP5	O75197-1.2	A1418S	Neutral	0.0
LRP5	O75197-1.2	A1418T	Neutral	0.0
LRP5	O75197-1.2	A1418V	Neutral	0.0
LRP5	O75197-1.2	A1418W	Neutral	0.0
LRP5	O75197-1.2	A1418Y	Neutral	0.0
LRP5	O75197-1.2	N1419A	Neutral	0.0
LRP5	O75197-1.2	N1419C	Neutral	0.0
LRP5	O75197-1.2	N1419D	Neutral	0.0
LRP5	O75197-1.2	N1419E	Neutral	0.0
LRP5	O75197-1.2	N1419F	Neutral	0.0
LRP5	O75197-1.2	N1419G	Neutral	0.0
LRP5	O75197-1.2	N1419H	Neutral	0.0
LRP5	O75197-1.2	N1419I	Neutral	0.0
LRP5	O75197-1.2	N1419K	Neutral	0.0
LRP5	O75197-1.2	N1419L	Neutral	0.0
LRP5	O75197-1.2	N1419M	Neutral	0.0
LRP5	O75197-1.2	N1419P	Neutral	0.0
LRP5	O75197-1.2	N1419Q	Neutral	0.0
LRP5	O75197-1.2	N1419R	Neutral	0.0
LRP5	O75197-1.2	N1419S	Neutral	0.0
LRP5	O75197-1.2	N1419T	Neutral	0.0
LRP5	O75197-1.2	N1419V	Neutral	0.0
LRP5	O75197-1.2	N1419W	Neutral	0.0
LRP5	O75197-1.2	N1419Y	Neutral	0.0
LRP5	O75197-1.2	G1420A	Neutral	0.0
LRP5	O75197-1.2	G1420C	Neutral	0.001
LRP5	O75197-1.2	G1420D	Neutral	0.0
LRP5	O75197-1.2	G1420E	Neutral	0.001
LRP5	O75197-1.2	G1420F	Neutral	0.001
LRP5	O75197-1.2	G1420H	Neutral	0.001
LRP5	O75197-1.2	G1420I	Neutral	0.002
LRP5	O75197-1.2	G1420K	Neutral	0.0
LRP5	O75197-1.2	G1420L	Neutral	0.002
LRP5	O75197-1.2	G1420M	Neutral	0.001
LRP5	O75197-1.2	G1420N	Neutral	0.0
LRP5	O75197-1.2	G1420P	Neutral	0.001
LRP5	O75197-1.2	G1420Q	Neutral	0.001
LRP5	O75197-1.2	G1420R	Neutral	0.0
LRP5	O75197-1.2	G1420S	Neutral	0.0
LRP5	O75197-1.2	G1420T	Neutral	0.001
LRP5	O75197-1.2	G1420V	Neutral	0.001
LRP5	O75197-1.2	G1420W	Neutral	0.0
LRP5	O75197-1.2	G1420Y	Neutral	0.001
LRP5	O75197-1.2	P1421A	Neutral	0.0
LRP5	O75197-1.2	P1421C	Neutral	0.005
LRP5	O75197-1.2	P1421D	Neutral	0.0
LRP5	O75197-1.2	P1421E	Neutral	0.0
LRP5	O75197-1.2	P1421F	Neutral	0.007
LRP5	O75197-1.2	P1421G	Neutral	0.001
LRP5	O75197-1.2	P1421H	Neutral	0.001
LRP5	O75197-1.2	P1421I	Neutral	0.002
LRP5	O75197-1.2	P1421K	Neutral	0.0
LRP5	O75197-1.2	P1421L	Neutral	0.003
LRP5	O75197-1.2	P1421M	Neutral	0.001
LRP5	O75197-1.2	P1421N	Neutral	0.001
LRP5	O75197-1.2	P1421Q	Neutral	0.0
LRP5	O75197-1.2	P1421R	Neutral	0.0
LRP5	O75197-1.2	P1421S	Neutral	0.0
LRP5	O75197-1.2	P1421T	Neutral	0.0
LRP5	O75197-1.2	P1421V	Neutral	0.001
LRP5	O75197-1.2	P1421W	Neutral	0.005
LRP5	O75197-1.2	P1421Y	Neutral	0.005
LRP5	O75197-1.2	F1422A	Neutral	0.001
LRP5	O75197-1.2	F1422C	Neutral	0.002
LRP5	O75197-1.2	F1422D	Neutral	0.001
LRP5	O75197-1.2	F1422E	Neutral	0.001
LRP5	O75197-1.2	F1422G	Neutral	0.002
LRP5	O75197-1.2	F1422H	Neutral	0.0
LRP5	O75197-1.2	F1422I	Neutral	0.0
LRP5	O75197-1.2	F1422K	Neutral	0.001
LRP5	O75197-1.2	F1422L	Neutral	0.0
LRP5	O75197-1.2	F1422M	Neutral	0.0
LRP5	O75197-1.2	F1422N	Neutral	0.001
LRP5	O75197-1.2	F1422P	Neutral	0.012
LRP5	O75197-1.2	F1422Q	Neutral	0.002
LRP5	O75197-1.2	F1422R	Neutral	0.001
LRP5	O75197-1.2	F1422S	Neutral	0.001
LRP5	O75197-1.2	F1422T	Neutral	0.001
LRP5	O75197-1.2	F1422V	Neutral	0.001
LRP5	O75197-1.2	F1422W	Neutral	0.0
LRP5	O75197-1.2	F1422Y	Neutral	0.0
LRP5	O75197-1.2	P1423A	Neutral	0.002
LRP5	O75197-1.2	P1423C	Neutral	0.024
LRP5	O75197-1.2	P1423D	Neutral	0.001
LRP5	O75197-1.2	P1423E	Neutral	0.001
LRP5	O75197-1.2	P1423F	Neutral	0.032
LRP5	O75197-1.2	P1423G	Neutral	0.005
LRP5	O75197-1.2	P1423H	Neutral	0.006
LRP5	O75197-1.2	P1423I	Neutral	0.011
LRP5	O75197-1.2	P1423K	Neutral	0.001
LRP5	O75197-1.2	P1423L	Neutral	0.012
LRP5	O75197-1.2	P1423M	Neutral	0.006
LRP5	O75197-1.2	P1423N	Neutral	0.003
LRP5	O75197-1.2	P1423Q	Neutral	0.001
LRP5	O75197-1.2	P1423R	Neutral	0.002
LRP5	O75197-1.2	P1423S	Neutral	0.002
LRP5	O75197-1.2	P1423T	Neutral	0.002
LRP5	O75197-1.2	P1423V	Neutral	0.006
LRP5	O75197-1.2	P1423W	Neutral	0.021
LRP5	O75197-1.2	P1423Y	Neutral	0.022
LRP5	O75197-1.2	H1424A	Neutral	0.018
LRP5	O75197-1.2	H1424C	Neutral	0.03
LRP5	O75197-1.2	H1424D	Neutral	0.003
LRP5	O75197-1.2	H1424E	Neutral	0.001
LRP5	O75197-1.2	H1424F	Neutral	0.002
LRP5	O75197-1.2	H1424G	Neutral	0.018
LRP5	O75197-1.2	H1424I	Neutral	0.015
LRP5	O75197-1.2	H1424K	Neutral	0.003
LRP5	O75197-1.2	H1424L	Neutral	0.017
LRP5	O75197-1.2	H1424M	Neutral	0.008
LRP5	O75197-1.2	H1424N	Neutral	0.0
LRP5	O75197-1.2	H1424P	Neutral	0.013
LRP5	O75197-1.2	H1424Q	Neutral	0.002
LRP5	O75197-1.2	H1424R	Neutral	0.001
LRP5	O75197-1.2	H1424S	Neutral	0.006
LRP5	O75197-1.2	H1424T	Neutral	0.019
LRP5	O75197-1.2	H1424V	Neutral	0.025
LRP5	O75197-1.2	H1424W	Neutral	0.003
LRP5	O75197-1.2	H1424Y	Neutral	0.0
LRP5	O75197-1.2	E1425A	Neutral	0.0
LRP5	O75197-1.2	E1425C	Neutral	0.004
LRP5	O75197-1.2	E1425D	Neutral	0.0
LRP5	O75197-1.2	E1425F	Neutral	0.001
LRP5	O75197-1.2	E1425G	Neutral	0.001
LRP5	O75197-1.2	E1425H	Neutral	0.0
LRP5	O75197-1.2	E1425I	Neutral	0.001
LRP5	O75197-1.2	E1425K	Neutral	0.0
LRP5	O75197-1.2	E1425L	Neutral	0.001
LRP5	O75197-1.2	E1425M	Neutral	0.0
LRP5	O75197-1.2	E1425N	Neutral	0.0
LRP5	O75197-1.2	E1425P	Neutral	0.0
LRP5	O75197-1.2	E1425Q	Neutral	0.0
LRP5	O75197-1.2	E1425R	Neutral	0.0
LRP5	O75197-1.2	E1425S	Neutral	0.0
LRP5	O75197-1.2	E1425T	Neutral	0.0
LRP5	O75197-1.2	E1425V	Neutral	0.0
LRP5	O75197-1.2	E1425W	Neutral	0.0
LRP5	O75197-1.2	E1425Y	Neutral	0.0
LRP5	O75197-1.2	Y1426A	Neutral	0.006
LRP5	O75197-1.2	Y1426C	Neutral	0.011
LRP5	O75197-1.2	Y1426D	Neutral	0.007
LRP5	O75197-1.2	Y1426E	Neutral	0.003
LRP5	O75197-1.2	Y1426F	Neutral	0.0
LRP5	O75197-1.2	Y1426G	Neutral	0.014
LRP5	O75197-1.2	Y1426H	Neutral	0.0
LRP5	O75197-1.2	Y1426I	Neutral	0.002
LRP5	O75197-1.2	Y1426K	Neutral	0.002
LRP5	O75197-1.2	Y1426L	Neutral	0.002
LRP5	O75197-1.2	Y1426M	Neutral	0.003
LRP5	O75197-1.2	Y1426N	Neutral	0.003
LRP5	O75197-1.2	Y1426P	Neutral	0.027
LRP5	O75197-1.2	Y1426Q	Neutral	0.001
LRP5	O75197-1.2	Y1426R	Neutral	0.002
LRP5	O75197-1.2	Y1426S	Neutral	0.005
LRP5	O75197-1.2	Y1426T	Neutral	0.006
LRP5	O75197-1.2	Y1426V	Neutral	0.003
LRP5	O75197-1.2	Y1426W	Neutral	0.0
LRP5	O75197-1.2	V1427A	Neutral	0.002
LRP5	O75197-1.2	V1427C	Neutral	0.009
LRP5	O75197-1.2	V1427D	Neutral	0.017
LRP5	O75197-1.2	V1427E	Neutral	0.006
LRP5	O75197-1.2	V1427F	Neutral	0.006
LRP5	O75197-1.2	V1427G	Neutral	0.031
LRP5	O75197-1.2	V1427H	Neutral	0.037
LRP5	O75197-1.2	V1427I	Neutral	0.0
LRP5	O75197-1.2	V1427K	Neutral	0.004
LRP5	O75197-1.2	V1427L	Neutral	0.001
LRP5	O75197-1.2	V1427M	Neutral	0.001
LRP5	O75197-1.2	V1427N	Neutral	0.02
LRP5	O75197-1.2	V1427P	Neutral	0.021
LRP5	O75197-1.2	V1427Q	Neutral	0.009
LRP5	O75197-1.2	V1427R	Neutral	0.013
LRP5	O75197-1.2	V1427S	Neutral	0.01
LRP5	O75197-1.2	V1427T	Neutral	0.002
LRP5	O75197-1.2	V1427W	Neutral	0.036
LRP5	O75197-1.2	V1427Y	Neutral	0.008
LRP5	O75197-1.2	S1428A	Neutral	0.0
LRP5	O75197-1.2	S1428C	Neutral	0.0
LRP5	O75197-1.2	S1428D	Neutral	0.0
LRP5	O75197-1.2	S1428E	Neutral	0.0
LRP5	O75197-1.2	S1428F	Neutral	0.0
LRP5	O75197-1.2	S1428G	Neutral	0.0
LRP5	O75197-1.2	S1428H	Neutral	0.0
LRP5	O75197-1.2	S1428I	Neutral	0.0
LRP5	O75197-1.2	S1428K	Neutral	0.0
LRP5	O75197-1.2	S1428L	Neutral	0.0
LRP5	O75197-1.2	S1428M	Neutral	0.0
LRP5	O75197-1.2	S1428N	Neutral	0.0
LRP5	O75197-1.2	S1428P	Neutral	0.0
LRP5	O75197-1.2	S1428Q	Neutral	0.0
LRP5	O75197-1.2	S1428R	Neutral	0.0
LRP5	O75197-1.2	S1428T	Neutral	0.0
LRP5	O75197-1.2	S1428V	Neutral	0.0
LRP5	O75197-1.2	S1428W	Neutral	0.0
LRP5	O75197-1.2	S1428Y	Neutral	0.0
LRP5	O75197-1.2	G1429A	Neutral	0.003
LRP5	O75197-1.2	G1429C	Neutral	0.041
LRP5	O75197-1.2	G1429D	Neutral	0.005
LRP5	O75197-1.2	G1429E	Neutral	0.018
LRP5	O75197-1.2	G1429F	Neutral	0.019
LRP5	O75197-1.2	G1429H	Neutral	0.028
LRP5	O75197-1.2	G1429I	Neutral	0.055
LRP5	O75197-1.2	G1429K	Neutral	0.013
LRP5	O75197-1.2	G1429L	Neutral	0.06
LRP5	O75197-1.2	G1429M	Neutral	0.031
LRP5	O75197-1.2	G1429N	Neutral	0.002
LRP5	O75197-1.2	G1429P	Neutral	0.017
LRP5	O75197-1.2	G1429Q	Neutral	0.026
LRP5	O75197-1.2	G1429R	Neutral	0.012
LRP5	O75197-1.2	G1429S	Neutral	0.004
LRP5	O75197-1.2	G1429T	Neutral	0.026
LRP5	O75197-1.2	G1429V	Neutral	0.032
LRP5	O75197-1.2	G1429W	Neutral	0.004
LRP5	O75197-1.2	G1429Y	Neutral	0.038
LRP5	O75197-1.2	T1430A	Neutral	0.0
LRP5	O75197-1.2	T1430C	Neutral	0.0
LRP5	O75197-1.2	T1430D	Neutral	0.0
LRP5	O75197-1.2	T1430E	Neutral	0.0
LRP5	O75197-1.2	T1430F	Neutral	0.0
LRP5	O75197-1.2	T1430G	Neutral	0.0
LRP5	O75197-1.2	T1430H	Neutral	0.001
LRP5	O75197-1.2	T1430I	Neutral	0.0
LRP5	O75197-1.2	T1430K	Neutral	0.0
LRP5	O75197-1.2	T1430L	Neutral	0.0
LRP5	O75197-1.2	T1430M	Neutral	0.0
LRP5	O75197-1.2	T1430N	Neutral	0.0
LRP5	O75197-1.2	T1430P	Neutral	0.0
LRP5	O75197-1.2	T1430Q	Neutral	0.0
LRP5	O75197-1.2	T1430R	Neutral	0.0
LRP5	O75197-1.2	T1430S	Neutral	0.0
LRP5	O75197-1.2	T1430V	Neutral	0.0
LRP5	O75197-1.2	T1430W	Neutral	0.0
LRP5	O75197-1.2	T1430Y	Neutral	0.0
LRP5	O75197-1.2	P1431A	Neutral	0.0
LRP5	O75197-1.2	P1431C	Neutral	0.003
LRP5	O75197-1.2	P1431D	Neutral	0.0
LRP5	O75197-1.2	P1431E	Neutral	0.0
LRP5	O75197-1.2	P1431F	Neutral	0.004
LRP5	O75197-1.2	P1431G	Neutral	0.001
LRP5	O75197-1.2	P1431H	Neutral	0.001
LRP5	O75197-1.2	P1431I	Neutral	0.001
LRP5	O75197-1.2	P1431K	Neutral	0.0
LRP5	O75197-1.2	P1431L	Neutral	0.001
LRP5	O75197-1.2	P1431M	Neutral	0.001
LRP5	O75197-1.2	P1431N	Neutral	0.0
LRP5	O75197-1.2	P1431Q	Neutral	0.0
LRP5	O75197-1.2	P1431R	Neutral	0.0
LRP5	O75197-1.2	P1431S	Neutral	0.0
LRP5	O75197-1.2	P1431T	Neutral	0.0
LRP5	O75197-1.2	P1431V	Neutral	0.001
LRP5	O75197-1.2	P1431W	Neutral	0.002
LRP5	O75197-1.2	P1431Y	Neutral	0.003
LRP5	O75197-1.2	H1432A	Neutral	0.002
LRP5	O75197-1.2	H1432C	Neutral	0.004
LRP5	O75197-1.2	H1432D	Neutral	0.0
LRP5	O75197-1.2	H1432E	Neutral	0.0
LRP5	O75197-1.2	H1432F	Neutral	0.0
LRP5	O75197-1.2	H1432G	Neutral	0.002
LRP5	O75197-1.2	H1432I	Neutral	0.002
LRP5	O75197-1.2	H1432K	Neutral	0.0
LRP5	O75197-1.2	H1432L	Neutral	0.002
LRP5	O75197-1.2	H1432M	Neutral	0.001
LRP5	O75197-1.2	H1432N	Neutral	0.0
LRP5	O75197-1.2	H1432P	Neutral	0.002
LRP5	O75197-1.2	H1432Q	Neutral	0.0
LRP5	O75197-1.2	H1432R	Neutral	0.0
LRP5	O75197-1.2	H1432S	Neutral	0.001
LRP5	O75197-1.2	H1432T	Neutral	0.002
LRP5	O75197-1.2	H1432V	Neutral	0.003
LRP5	O75197-1.2	H1432W	Neutral	0.0
LRP5	O75197-1.2	H1432Y	Neutral	0.0
LRP5	O75197-1.2	V1433A	Neutral	0.002
LRP5	O75197-1.2	V1433C	Neutral	0.009
LRP5	O75197-1.2	V1433D	Neutral	0.018
LRP5	O75197-1.2	V1433E	Neutral	0.007
LRP5	O75197-1.2	V1433F	Neutral	0.007
LRP5	O75197-1.2	V1433G	Neutral	0.032
LRP5	O75197-1.2	V1433H	Neutral	0.039
LRP5	O75197-1.2	V1433I	Neutral	0.0
LRP5	O75197-1.2	V1433K	Neutral	0.005
LRP5	O75197-1.2	V1433L	Neutral	0.001
LRP5	O75197-1.2	V1433M	Neutral	0.001
LRP5	O75197-1.2	V1433N	Neutral	0.021
LRP5	O75197-1.2	V1433P	Neutral	0.022
LRP5	O75197-1.2	V1433Q	Neutral	0.01
LRP5	O75197-1.2	V1433R	Neutral	0.014
LRP5	O75197-1.2	V1433S	Neutral	0.011
LRP5	O75197-1.2	V1433T	Neutral	0.002
LRP5	O75197-1.2	V1433W	Neutral	0.038
LRP5	O75197-1.2	V1433Y	Neutral	0.009
LRP5	O75197-1.2	P1434A	Neutral	0.043
LRP5	O75197-1.2	P1434C	Neutral	0.329
LRP5	O75197-1.2	P1434D	Neutral	0.017
LRP5	O75197-1.2	P1434E	Neutral	0.019
LRP5	O75197-1.2	P1434F	Neutral	0.404
LRP5	O75197-1.2	P1434G	Neutral	0.092
LRP5	O75197-1.2	P1434H	Neutral	0.104
LRP5	O75197-1.2	P1434I	Neutral	0.183
LRP5	O75197-1.2	P1434K	Neutral	0.013
LRP5	O75197-1.2	P1434L	Neutral	0.197
LRP5	O75197-1.2	P1434M	Neutral	0.109
LRP5	O75197-1.2	P1434N	Neutral	0.059
LRP5	O75197-1.2	P1434Q	Neutral	0.027
LRP5	O75197-1.2	P1434R	Neutral	0.038
LRP5	O75197-1.2	P1434S	Neutral	0.032
LRP5	O75197-1.2	P1434T	Neutral	0.042
LRP5	O75197-1.2	P1434V	Neutral	0.114
LRP5	O75197-1.2	P1434W	Neutral	0.3
LRP5	O75197-1.2	P1434Y	Neutral	0.316
LRP5	O75197-1.2	L1435A	Neutral	0.003
LRP5	O75197-1.2	L1435C	Neutral	0.005
LRP5	O75197-1.2	L1435D	Neutral	0.028
LRP5	O75197-1.2	L1435E	Neutral	0.011
LRP5	O75197-1.2	L1435F	Neutral	0.003
LRP5	O75197-1.2	L1435G	Neutral	0.052
LRP5	O75197-1.2	L1435H	Neutral	0.022
LRP5	O75197-1.2	L1435I	Neutral	0.0
LRP5	O75197-1.2	L1435K	Neutral	0.003
LRP5	O75197-1.2	L1435M	Neutral	0.0
LRP5	O75197-1.2	L1435N	Neutral	0.011
LRP5	O75197-1.2	L1435P	Neutral	0.035
LRP5	O75197-1.2	L1435Q	Neutral	0.005
LRP5	O75197-1.2	L1435R	Neutral	0.003
LRP5	O75197-1.2	L1435S	Neutral	0.006
LRP5	O75197-1.2	L1435T	Neutral	0.003
LRP5	O75197-1.2	L1435V	Neutral	0.001
LRP5	O75197-1.2	L1435W	Neutral	0.017
LRP5	O75197-1.2	L1435Y	Neutral	0.005
LRP5	O75197-1.2	N1436A	Neutral	0.001
LRP5	O75197-1.2	N1436C	Neutral	0.001
LRP5	O75197-1.2	N1436D	Neutral	0.0
LRP5	O75197-1.2	N1436E	Neutral	0.0
LRP5	O75197-1.2	N1436F	Neutral	0.0
LRP5	O75197-1.2	N1436G	Neutral	0.0
LRP5	O75197-1.2	N1436H	Neutral	0.0
LRP5	O75197-1.2	N1436I	Neutral	0.0
LRP5	O75197-1.2	N1436K	Neutral	0.0
LRP5	O75197-1.2	N1436L	Neutral	0.0
LRP5	O75197-1.2	N1436M	Neutral	0.0
LRP5	O75197-1.2	N1436P	Neutral	0.0
LRP5	O75197-1.2	N1436Q	Neutral	0.0
LRP5	O75197-1.2	N1436R	Neutral	0.0
LRP5	O75197-1.2	N1436S	Neutral	0.0
LRP5	O75197-1.2	N1436T	Neutral	0.0
LRP5	O75197-1.2	N1436V	Neutral	0.001
LRP5	O75197-1.2	N1436W	Neutral	0.001
LRP5	O75197-1.2	N1436Y	Neutral	0.0
LRP5	O75197-1.2	F1437A	Neutral	0.001
LRP5	O75197-1.2	F1437C	Neutral	0.002
LRP5	O75197-1.2	F1437D	Neutral	0.001
LRP5	O75197-1.2	F1437E	Neutral	0.001
LRP5	O75197-1.2	F1437G	Neutral	0.002
LRP5	O75197-1.2	F1437H	Neutral	0.0
LRP5	O75197-1.2	F1437I	Neutral	0.0
LRP5	O75197-1.2	F1437K	Neutral	0.001
LRP5	O75197-1.2	F1437L	Neutral	0.0
LRP5	O75197-1.2	F1437M	Neutral	0.0
LRP5	O75197-1.2	F1437N	Neutral	0.001
LRP5	O75197-1.2	F1437P	Neutral	0.014
LRP5	O75197-1.2	F1437Q	Neutral	0.002
LRP5	O75197-1.2	F1437R	Neutral	0.001
LRP5	O75197-1.2	F1437S	Neutral	0.001
LRP5	O75197-1.2	F1437T	Neutral	0.001
LRP5	O75197-1.2	F1437V	Neutral	0.001
LRP5	O75197-1.2	F1437W	Neutral	0.0
LRP5	O75197-1.2	F1437Y	Neutral	0.0
LRP5	O75197-1.2	I1438A	Neutral	0.0
LRP5	O75197-1.2	I1438C	Neutral	0.0
LRP5	O75197-1.2	I1438D	Neutral	0.0
LRP5	O75197-1.2	I1438E	Neutral	0.0
LRP5	O75197-1.2	I1438F	Neutral	0.0
LRP5	O75197-1.2	I1438G	Neutral	0.002
LRP5	O75197-1.2	I1438H	Neutral	0.001
LRP5	O75197-1.2	I1438K	Neutral	0.0
LRP5	O75197-1.2	I1438L	Neutral	0.0
LRP5	O75197-1.2	I1438M	Neutral	0.0
LRP5	O75197-1.2	I1438N	Neutral	0.0
LRP5	O75197-1.2	I1438P	Neutral	0.001
LRP5	O75197-1.2	I1438Q	Neutral	0.001
LRP5	O75197-1.2	I1438R	Neutral	0.0
LRP5	O75197-1.2	I1438S	Neutral	0.0
LRP5	O75197-1.2	I1438T	Neutral	0.0
LRP5	O75197-1.2	I1438V	Neutral	0.0
LRP5	O75197-1.2	I1438W	Neutral	0.002
LRP5	O75197-1.2	I1438Y	Neutral	0.0
LRP5	O75197-1.2	A1439C	Neutral	0.0
LRP5	O75197-1.2	A1439D	Neutral	0.0
LRP5	O75197-1.2	A1439E	Neutral	0.0
LRP5	O75197-1.2	A1439F	Neutral	0.0
LRP5	O75197-1.2	A1439G	Neutral	0.0
LRP5	O75197-1.2	A1439H	Neutral	0.001
LRP5	O75197-1.2	A1439I	Neutral	0.0
LRP5	O75197-1.2	A1439K	Neutral	0.0
LRP5	O75197-1.2	A1439L	Neutral	0.0
LRP5	O75197-1.2	A1439M	Neutral	0.0
LRP5	O75197-1.2	A1439N	Neutral	0.0
LRP5	O75197-1.2	A1439P	Neutral	0.0
LRP5	O75197-1.2	A1439Q	Neutral	0.0
LRP5	O75197-1.2	A1439R	Neutral	0.0
LRP5	O75197-1.2	A1439S	Neutral	0.0
LRP5	O75197-1.2	A1439T	Neutral	0.0
LRP5	O75197-1.2	A1439V	Neutral	0.0
LRP5	O75197-1.2	A1439W	Neutral	0.0
LRP5	O75197-1.2	A1439Y	Neutral	0.0
LRP5	O75197-1.2	P1440A	Neutral	0.0
LRP5	O75197-1.2	P1440C	Neutral	0.005
LRP5	O75197-1.2	P1440D	Neutral	0.0
LRP5	O75197-1.2	P1440E	Neutral	0.0
LRP5	O75197-1.2	P1440F	Neutral	0.007
LRP5	O75197-1.2	P1440G	Neutral	0.001
LRP5	O75197-1.2	P1440H	Neutral	0.001
LRP5	O75197-1.2	P1440I	Neutral	0.002
LRP5	O75197-1.2	P1440K	Neutral	0.0
LRP5	O75197-1.2	P1440L	Neutral	0.003
LRP5	O75197-1.2	P1440M	Neutral	0.001
LRP5	O75197-1.2	P1440N	Neutral	0.001
LRP5	O75197-1.2	P1440Q	Neutral	0.0
LRP5	O75197-1.2	P1440R	Neutral	0.0
LRP5	O75197-1.2	P1440S	Neutral	0.0
LRP5	O75197-1.2	P1440T	Neutral	0.0
LRP5	O75197-1.2	P1440V	Neutral	0.001
LRP5	O75197-1.2	P1440W	Neutral	0.005
LRP5	O75197-1.2	P1440Y	Neutral	0.005
LRP5	O75197-1.2	G1441A	Neutral	0.0
LRP5	O75197-1.2	G1441C	Neutral	0.001
LRP5	O75197-1.2	G1441D	Neutral	0.0
LRP5	O75197-1.2	G1441E	Neutral	0.0
LRP5	O75197-1.2	G1441F	Neutral	0.0
LRP5	O75197-1.2	G1441H	Neutral	0.0
LRP5	O75197-1.2	G1441I	Neutral	0.001
LRP5	O75197-1.2	G1441K	Neutral	0.0
LRP5	O75197-1.2	G1441L	Neutral	0.001
LRP5	O75197-1.2	G1441M	Neutral	0.0
LRP5	O75197-1.2	G1441N	Neutral	0.0
LRP5	O75197-1.2	G1441P	Neutral	0.0
LRP5	O75197-1.2	G1441Q	Neutral	0.0
LRP5	O75197-1.2	G1441R	Neutral	0.0
LRP5	O75197-1.2	G1441S	Neutral	0.0
LRP5	O75197-1.2	G1441T	Neutral	0.0
LRP5	O75197-1.2	G1441V	Neutral	0.0
LRP5	O75197-1.2	G1441W	Neutral	0.0
LRP5	O75197-1.2	G1441Y	Neutral	0.0
LRP5	O75197-1.2	G1442A	Neutral	0.0
LRP5	O75197-1.2	G1442C	Neutral	0.0
LRP5	O75197-1.2	G1442D	Neutral	0.0
LRP5	O75197-1.2	G1442E	Neutral	0.0
LRP5	O75197-1.2	G1442F	Neutral	0.0
LRP5	O75197-1.2	G1442H	Neutral	0.0
LRP5	O75197-1.2	G1442I	Neutral	0.001
LRP5	O75197-1.2	G1442K	Neutral	0.0
LRP5	O75197-1.2	G1442L	Neutral	0.001
LRP5	O75197-1.2	G1442M	Neutral	0.0
LRP5	O75197-1.2	G1442N	Neutral	0.0
LRP5	O75197-1.2	G1442P	Neutral	0.0
LRP5	O75197-1.2	G1442Q	Neutral	0.0
LRP5	O75197-1.2	G1442R	Neutral	0.0
LRP5	O75197-1.2	G1442S	Neutral	0.0
LRP5	O75197-1.2	G1442T	Neutral	0.0
LRP5	O75197-1.2	G1442V	Neutral	0.0
LRP5	O75197-1.2	G1442W	Neutral	0.0
LRP5	O75197-1.2	G1442Y	Neutral	0.0
LRP5	O75197-1.2	S1443A	Neutral	0.0
LRP5	O75197-1.2	S1443C	Neutral	0.002
LRP5	O75197-1.2	S1443D	Neutral	0.001
LRP5	O75197-1.2	S1443E	Neutral	0.001
LRP5	O75197-1.2	S1443F	Neutral	0.003
LRP5	O75197-1.2	S1443G	Neutral	0.002
LRP5	O75197-1.2	S1443H	Neutral	0.005
LRP5	O75197-1.2	S1443I	Neutral	0.003
LRP5	O75197-1.2	S1443K	Neutral	0.001
LRP5	O75197-1.2	S1443L	Neutral	0.003
LRP5	O75197-1.2	S1443M	Neutral	0.002
LRP5	O75197-1.2	S1443N	Neutral	0.0
LRP5	O75197-1.2	S1443P	Neutral	0.003
LRP5	O75197-1.2	S1443Q	Neutral	0.002
LRP5	O75197-1.2	S1443R	Neutral	0.002
LRP5	O75197-1.2	S1443T	Neutral	0.0
LRP5	O75197-1.2	S1443V	Neutral	0.005
LRP5	O75197-1.2	S1443W	Neutral	0.006
LRP5	O75197-1.2	S1443Y	Neutral	0.006
LRP5	O75197-1.2	Q1444A	Neutral	0.0
LRP5	O75197-1.2	Q1444C	Neutral	0.002
LRP5	O75197-1.2	Q1444D	Neutral	0.0
LRP5	O75197-1.2	Q1444E	Neutral	0.0
LRP5	O75197-1.2	Q1444F	Neutral	0.001
LRP5	O75197-1.2	Q1444G	Neutral	0.001
LRP5	O75197-1.2	Q1444H	Neutral	0.0
LRP5	O75197-1.2	Q1444I	Neutral	0.001
LRP5	O75197-1.2	Q1444K	Neutral	0.0
LRP5	O75197-1.2	Q1444L	Neutral	0.0
LRP5	O75197-1.2	Q1444M	Neutral	0.0
LRP5	O75197-1.2	Q1444N	Neutral	0.0
LRP5	O75197-1.2	Q1444P	Neutral	0.0
LRP5	O75197-1.2	Q1444R	Neutral	0.0
LRP5	O75197-1.2	Q1444S	Neutral	0.0
LRP5	O75197-1.2	Q1444T	Neutral	0.0
LRP5	O75197-1.2	Q1444V	Neutral	0.0
LRP5	O75197-1.2	Q1444W	Neutral	0.0
LRP5	O75197-1.2	Q1444Y	Neutral	0.0
LRP5	O75197-1.2	H1445A	Neutral	0.001
LRP5	O75197-1.2	H1445C	Neutral	0.003
LRP5	O75197-1.2	H1445D	Neutral	0.0
LRP5	O75197-1.2	H1445E	Neutral	0.0
LRP5	O75197-1.2	H1445F	Neutral	0.0
LRP5	O75197-1.2	H1445G	Neutral	0.001
LRP5	O75197-1.2	H1445I	Neutral	0.001
LRP5	O75197-1.2	H1445K	Neutral	0.0
LRP5	O75197-1.2	H1445L	Neutral	0.001
LRP5	O75197-1.2	H1445M	Neutral	0.001
LRP5	O75197-1.2	H1445N	Neutral	0.0
LRP5	O75197-1.2	H1445P	Neutral	0.001
LRP5	O75197-1.2	H1445Q	Neutral	0.0
LRP5	O75197-1.2	H1445R	Neutral	0.0
LRP5	O75197-1.2	H1445S	Neutral	0.0
LRP5	O75197-1.2	H1445T	Neutral	0.002
LRP5	O75197-1.2	H1445V	Neutral	0.002
LRP5	O75197-1.2	H1445W	Neutral	0.0
LRP5	O75197-1.2	H1445Y	Neutral	0.0
LRP5	O75197-1.2	G1446A	Neutral	0.004
LRP5	O75197-1.2	G1446C	Neutral	0.053
LRP5	O75197-1.2	G1446D	Neutral	0.007
LRP5	O75197-1.2	G1446E	Neutral	0.024
LRP5	O75197-1.2	G1446F	Neutral	0.025
LRP5	O75197-1.2	G1446H	Neutral	0.036
LRP5	O75197-1.2	G1446I	Neutral	0.071
LRP5	O75197-1.2	G1446K	Neutral	0.017
LRP5	O75197-1.2	G1446L	Neutral	0.078
LRP5	O75197-1.2	G1446M	Neutral	0.04
LRP5	O75197-1.2	G1446N	Neutral	0.003
LRP5	O75197-1.2	G1446P	Neutral	0.023
LRP5	O75197-1.2	G1446Q	Neutral	0.034
LRP5	O75197-1.2	G1446R	Neutral	0.016
LRP5	O75197-1.2	G1446S	Neutral	0.005
LRP5	O75197-1.2	G1446T	Neutral	0.034
LRP5	O75197-1.2	G1446V	Neutral	0.042
LRP5	O75197-1.2	G1446W	Neutral	0.005
LRP5	O75197-1.2	G1446Y	Neutral	0.05
LRP5	O75197-1.2	P1447A	Neutral	0.0
LRP5	O75197-1.2	P1447C	Neutral	0.001
LRP5	O75197-1.2	P1447D	Neutral	0.0
LRP5	O75197-1.2	P1447E	Neutral	0.0
LRP5	O75197-1.2	P1447F	Neutral	0.001
LRP5	O75197-1.2	P1447G	Neutral	0.0
LRP5	O75197-1.2	P1447H	Neutral	0.0
LRP5	O75197-1.2	P1447I	Neutral	0.0
LRP5	O75197-1.2	P1447K	Neutral	0.0
LRP5	O75197-1.2	P1447L	Neutral	0.0
LRP5	O75197-1.2	P1447M	Neutral	0.0
LRP5	O75197-1.2	P1447N	Neutral	0.0
LRP5	O75197-1.2	P1447Q	Neutral	0.0
LRP5	O75197-1.2	P1447R	Neutral	0.0
LRP5	O75197-1.2	P1447S	Neutral	0.0
LRP5	O75197-1.2	P1447T	Neutral	0.0
LRP5	O75197-1.2	P1447V	Neutral	0.0
LRP5	O75197-1.2	P1447W	Neutral	0.001
LRP5	O75197-1.2	P1447Y	Neutral	0.001
LRP5	O75197-1.2	F1448A	Neutral	0.001
LRP5	O75197-1.2	F1448C	Neutral	0.002
LRP5	O75197-1.2	F1448D	Neutral	0.001
LRP5	O75197-1.2	F1448E	Neutral	0.002
LRP5	O75197-1.2	F1448G	Neutral	0.003
LRP5	O75197-1.2	F1448H	Neutral	0.0
LRP5	O75197-1.2	F1448I	Neutral	0.001
LRP5	O75197-1.2	F1448K	Neutral	0.001
LRP5	O75197-1.2	F1448L	Neutral	0.0
LRP5	O75197-1.2	F1448M	Neutral	0.0
LRP5	O75197-1.2	F1448N	Neutral	0.002
LRP5	O75197-1.2	F1448P	Neutral	0.016
LRP5	O75197-1.2	F1448Q	Neutral	0.002
LRP5	O75197-1.2	F1448R	Neutral	0.001
LRP5	O75197-1.2	F1448S	Neutral	0.001
LRP5	O75197-1.2	F1448T	Neutral	0.001
LRP5	O75197-1.2	F1448V	Neutral	0.001
LRP5	O75197-1.2	F1448W	Neutral	0.0
LRP5	O75197-1.2	F1448Y	Neutral	0.0
LRP5	O75197-1.2	T1449A	Neutral	0.0
LRP5	O75197-1.2	T1449C	Neutral	0.0
LRP5	O75197-1.2	T1449D	Neutral	0.0
LRP5	O75197-1.2	T1449E	Neutral	0.0
LRP5	O75197-1.2	T1449F	Neutral	0.0
LRP5	O75197-1.2	T1449G	Neutral	0.0
LRP5	O75197-1.2	T1449H	Neutral	0.001
LRP5	O75197-1.2	T1449I	Neutral	0.0
LRP5	O75197-1.2	T1449K	Neutral	0.0
LRP5	O75197-1.2	T1449L	Neutral	0.0
LRP5	O75197-1.2	T1449M	Neutral	0.0
LRP5	O75197-1.2	T1449N	Neutral	0.0
LRP5	O75197-1.2	T1449P	Neutral	0.0
LRP5	O75197-1.2	T1449Q	Neutral	0.0
LRP5	O75197-1.2	T1449R	Neutral	0.0
LRP5	O75197-1.2	T1449S	Neutral	0.0
LRP5	O75197-1.2	T1449V	Neutral	0.0
LRP5	O75197-1.2	T1449W	Neutral	0.0
LRP5	O75197-1.2	T1449Y	Neutral	0.0
LRP5	O75197-1.2	G1450A	Neutral	0.01
LRP5	O75197-1.2	G1450C	Neutral	0.137
LRP5	O75197-1.2	G1450D	Neutral	0.02
LRP5	O75197-1.2	G1450E	Neutral	0.064
LRP5	O75197-1.2	G1450F	Neutral	0.066
LRP5	O75197-1.2	G1450H	Neutral	0.096
LRP5	O75197-1.2	G1450I	Neutral	0.178
LRP5	O75197-1.2	G1450K	Neutral	0.046
LRP5	O75197-1.2	G1450L	Neutral	0.192
LRP5	O75197-1.2	G1450M	Neutral	0.106
LRP5	O75197-1.2	G1450N	Neutral	0.008
LRP5	O75197-1.2	G1450P	Neutral	0.061
LRP5	O75197-1.2	G1450Q	Neutral	0.089
LRP5	O75197-1.2	G1450R	Neutral	0.044
LRP5	O75197-1.2	G1450S	Neutral	0.013
LRP5	O75197-1.2	G1450T	Neutral	0.09
LRP5	O75197-1.2	G1450V	Neutral	0.111
LRP5	O75197-1.2	G1450W	Neutral	0.015
LRP5	O75197-1.2	G1450Y	Neutral	0.129
LRP5	O75197-1.2	I1451A	Neutral	0.0
LRP5	O75197-1.2	I1451C	Neutral	0.0
LRP5	O75197-1.2	I1451D	Neutral	0.0
LRP5	O75197-1.2	I1451E	Neutral	0.0
LRP5	O75197-1.2	I1451F	Neutral	0.0
LRP5	O75197-1.2	I1451G	Neutral	0.001
LRP5	O75197-1.2	I1451H	Neutral	0.0
LRP5	O75197-1.2	I1451K	Neutral	0.0
LRP5	O75197-1.2	I1451L	Neutral	0.0
LRP5	O75197-1.2	I1451M	Neutral	0.0
LRP5	O75197-1.2	I1451N	Neutral	0.0
LRP5	O75197-1.2	I1451P	Neutral	0.001
LRP5	O75197-1.2	I1451Q	Neutral	0.0
LRP5	O75197-1.2	I1451R	Neutral	0.0
LRP5	O75197-1.2	I1451S	Neutral	0.0
LRP5	O75197-1.2	I1451T	Neutral	0.0
LRP5	O75197-1.2	I1451V	Neutral	0.0
LRP5	O75197-1.2	I1451W	Neutral	0.001
LRP5	O75197-1.2	I1451Y	Neutral	0.0
LRP5	O75197-1.2	A1452C	Neutral	0.0
LRP5	O75197-1.2	A1452D	Neutral	0.0
LRP5	O75197-1.2	A1452E	Neutral	0.0
LRP5	O75197-1.2	A1452F	Neutral	0.0
LRP5	O75197-1.2	A1452G	Neutral	0.0
LRP5	O75197-1.2	A1452H	Neutral	0.0
LRP5	O75197-1.2	A1452I	Neutral	0.0
LRP5	O75197-1.2	A1452K	Neutral	0.0
LRP5	O75197-1.2	A1452L	Neutral	0.0
LRP5	O75197-1.2	A1452M	Neutral	0.0
LRP5	O75197-1.2	A1452N	Neutral	0.0
LRP5	O75197-1.2	A1452P	Neutral	0.0
LRP5	O75197-1.2	A1452Q	Neutral	0.0
LRP5	O75197-1.2	A1452R	Neutral	0.0
LRP5	O75197-1.2	A1452S	Neutral	0.0
LRP5	O75197-1.2	A1452T	Neutral	0.0
LRP5	O75197-1.2	A1452V	Neutral	0.0
LRP5	O75197-1.2	A1452W	Neutral	0.0
LRP5	O75197-1.2	A1452Y	Neutral	0.0
LRP5	O75197-1.2	C1453A	Neutral	0.001
LRP5	O75197-1.2	C1453D	Neutral	0.006
LRP5	O75197-1.2	C1453E	Neutral	0.019
LRP5	O75197-1.2	C1453F	Neutral	0.004
LRP5	O75197-1.2	C1453G	Neutral	0.011
LRP5	O75197-1.2	C1453H	Neutral	0.013
LRP5	O75197-1.2	C1453I	Neutral	0.001
LRP5	O75197-1.2	C1453K	Neutral	0.005
LRP5	O75197-1.2	C1453L	Neutral	0.002
LRP5	O75197-1.2	C1453M	Neutral	0.002
LRP5	O75197-1.2	C1453N	Neutral	0.007
LRP5	O75197-1.2	C1453P	Neutral	0.022
LRP5	O75197-1.2	C1453Q	Neutral	0.009
LRP5	O75197-1.2	C1453R	Neutral	0.004
LRP5	O75197-1.2	C1453S	Neutral	0.001
LRP5	O75197-1.2	C1453T	Neutral	0.002
LRP5	O75197-1.2	C1453V	Neutral	0.002
LRP5	O75197-1.2	C1453W	Neutral	0.003
LRP5	O75197-1.2	C1453Y	Neutral	0.008
LRP5	O75197-1.2	G1454A	Neutral	0.003
LRP5	O75197-1.2	G1454C	Neutral	0.049
LRP5	O75197-1.2	G1454D	Neutral	0.007
LRP5	O75197-1.2	G1454E	Neutral	0.022
LRP5	O75197-1.2	G1454F	Neutral	0.023
LRP5	O75197-1.2	G1454H	Neutral	0.033
LRP5	O75197-1.2	G1454I	Neutral	0.066
LRP5	O75197-1.2	G1454K	Neutral	0.015
LRP5	O75197-1.2	G1454L	Neutral	0.072
LRP5	O75197-1.2	G1454M	Neutral	0.038
LRP5	O75197-1.2	G1454N	Neutral	0.003
LRP5	O75197-1.2	G1454P	Neutral	0.021
LRP5	O75197-1.2	G1454Q	Neutral	0.031
LRP5	O75197-1.2	G1454R	Neutral	0.015
LRP5	O75197-1.2	G1454S	Neutral	0.004
LRP5	O75197-1.2	G1454T	Neutral	0.031
LRP5	O75197-1.2	G1454V	Neutral	0.039
LRP5	O75197-1.2	G1454W	Neutral	0.005
LRP5	O75197-1.2	G1454Y	Neutral	0.046
LRP5	O75197-1.2	K1455A	Neutral	0.024
LRP5	O75197-1.2	K1455C	Neutral	0.113
LRP5	O75197-1.2	K1455D	Neutral	0.062
LRP5	O75197-1.2	K1455E	Neutral	0.007
LRP5	O75197-1.2	K1455F	Neutral	0.063
LRP5	O75197-1.2	K1455G	Neutral	0.087
LRP5	O75197-1.2	K1455H	Neutral	0.03
LRP5	O75197-1.2	K1455I	Neutral	0.061
LRP5	O75197-1.2	K1455L	Neutral	0.023
LRP5	O75197-1.2	K1455M	Neutral	0.012
LRP5	O75197-1.2	K1455N	Neutral	0.019
LRP5	O75197-1.2	K1455P	Neutral	0.017
LRP5	O75197-1.2	K1455Q	Neutral	0.005
LRP5	O75197-1.2	K1455R	Neutral	0.003
LRP5	O75197-1.2	K1455S	Neutral	0.011
LRP5	O75197-1.2	K1455T	Neutral	0.026
LRP5	O75197-1.2	K1455V	Neutral	0.034
LRP5	O75197-1.2	K1455W	Neutral	0.041
LRP5	O75197-1.2	K1455Y	Neutral	0.044
LRP5	O75197-1.2	S1456A	Neutral	0.0
LRP5	O75197-1.2	S1456C	Neutral	0.002
LRP5	O75197-1.2	S1456D	Neutral	0.001
LRP5	O75197-1.2	S1456E	Neutral	0.001
LRP5	O75197-1.2	S1456F	Neutral	0.003
LRP5	O75197-1.2	S1456G	Neutral	0.002
LRP5	O75197-1.2	S1456H	Neutral	0.005
LRP5	O75197-1.2	S1456I	Neutral	0.003
LRP5	O75197-1.2	S1456K	Neutral	0.001
LRP5	O75197-1.2	S1456L	Neutral	0.004
LRP5	O75197-1.2	S1456M	Neutral	0.002
LRP5	O75197-1.2	S1456N	Neutral	0.0
LRP5	O75197-1.2	S1456P	Neutral	0.003
LRP5	O75197-1.2	S1456Q	Neutral	0.002
LRP5	O75197-1.2	S1456R	Neutral	0.002
LRP5	O75197-1.2	S1456T	Neutral	0.001
LRP5	O75197-1.2	S1456V	Neutral	0.006
LRP5	O75197-1.2	S1456W	Neutral	0.006
LRP5	O75197-1.2	S1456Y	Neutral	0.007
LRP5	O75197-1.2	M1457A	Neutral	0.001
LRP5	O75197-1.2	M1457C	Neutral	0.001
LRP5	O75197-1.2	M1457D	Neutral	0.002
LRP5	O75197-1.2	M1457E	Neutral	0.001
LRP5	O75197-1.2	M1457F	Neutral	0.0
LRP5	O75197-1.2	M1457G	Neutral	0.004
LRP5	O75197-1.2	M1457H	Neutral	0.002
LRP5	O75197-1.2	M1457I	Neutral	0.0
LRP5	O75197-1.2	M1457K	Neutral	0.0
LRP5	O75197-1.2	M1457L	Neutral	0.0
LRP5	O75197-1.2	M1457N	Neutral	0.001
LRP5	O75197-1.2	M1457P	Neutral	0.003
LRP5	O75197-1.2	M1457Q	Neutral	0.0
LRP5	O75197-1.2	M1457R	Neutral	0.0
LRP5	O75197-1.2	M1457S	Neutral	0.0
LRP5	O75197-1.2	M1457T	Neutral	0.001
LRP5	O75197-1.2	M1457V	Neutral	0.0
LRP5	O75197-1.2	M1457W	Neutral	0.001
LRP5	O75197-1.2	M1457Y	Neutral	0.001
LRP5	O75197-1.2	M1458A	Neutral	0.001
LRP5	O75197-1.2	M1458C	Neutral	0.002
LRP5	O75197-1.2	M1458D	Neutral	0.003
LRP5	O75197-1.2	M1458E	Neutral	0.001
LRP5	O75197-1.2	M1458F	Neutral	0.0
LRP5	O75197-1.2	M1458G	Neutral	0.006
LRP5	O75197-1.2	M1458H	Neutral	0.003
LRP5	O75197-1.2	M1458I	Neutral	0.0
LRP5	O75197-1.2	M1458K	Neutral	0.0
LRP5	O75197-1.2	M1458L	Neutral	0.0
LRP5	O75197-1.2	M1458N	Neutral	0.001
LRP5	O75197-1.2	M1458P	Neutral	0.004
LRP5	O75197-1.2	M1458Q	Neutral	0.0
LRP5	O75197-1.2	M1458R	Neutral	0.0
LRP5	O75197-1.2	M1458S	Neutral	0.001
LRP5	O75197-1.2	M1458T	Neutral	0.001
LRP5	O75197-1.2	M1458V	Neutral	0.0
LRP5	O75197-1.2	M1458W	Neutral	0.001
LRP5	O75197-1.2	M1458Y	Neutral	0.002
LRP5	O75197-1.2	S1459A	Neutral	0.0
LRP5	O75197-1.2	S1459C	Neutral	0.0
LRP5	O75197-1.2	S1459D	Neutral	0.0
LRP5	O75197-1.2	S1459E	Neutral	0.0
LRP5	O75197-1.2	S1459F	Neutral	0.001
LRP5	O75197-1.2	S1459G	Neutral	0.0
LRP5	O75197-1.2	S1459H	Neutral	0.001
LRP5	O75197-1.2	S1459I	Neutral	0.001
LRP5	O75197-1.2	S1459K	Neutral	0.0
LRP5	O75197-1.2	S1459L	Neutral	0.001
LRP5	O75197-1.2	S1459M	Neutral	0.0
LRP5	O75197-1.2	S1459N	Neutral	0.0
LRP5	O75197-1.2	S1459P	Neutral	0.001
LRP5	O75197-1.2	S1459Q	Neutral	0.0
LRP5	O75197-1.2	S1459R	Neutral	0.0
LRP5	O75197-1.2	S1459T	Neutral	0.0
LRP5	O75197-1.2	S1459V	Neutral	0.001
LRP5	O75197-1.2	S1459W	Neutral	0.001
LRP5	O75197-1.2	S1459Y	Neutral	0.001
LRP5	O75197-1.2	S1460A	Neutral	0.0
LRP5	O75197-1.2	S1460C	Neutral	0.001
LRP5	O75197-1.2	S1460D	Neutral	0.001
LRP5	O75197-1.2	S1460E	Neutral	0.001
LRP5	O75197-1.2	S1460F	Neutral	0.002
LRP5	O75197-1.2	S1460G	Neutral	0.001
LRP5	O75197-1.2	S1460H	Neutral	0.003
LRP5	O75197-1.2	S1460I	Neutral	0.002
LRP5	O75197-1.2	S1460K	Neutral	0.0
LRP5	O75197-1.2	S1460L	Neutral	0.002
LRP5	O75197-1.2	S1460M	Neutral	0.001
LRP5	O75197-1.2	S1460N	Neutral	0.0
LRP5	O75197-1.2	S1460P	Neutral	0.002
LRP5	O75197-1.2	S1460Q	Neutral	0.001
LRP5	O75197-1.2	S1460R	Neutral	0.001
LRP5	O75197-1.2	S1460T	Neutral	0.0
LRP5	O75197-1.2	S1460V	Neutral	0.004
LRP5	O75197-1.2	S1460W	Neutral	0.004
LRP5	O75197-1.2	S1460Y	Neutral	0.004
LRP5	O75197-1.2	V1461A	Neutral	0.0
LRP5	O75197-1.2	V1461C	Neutral	0.0
LRP5	O75197-1.2	V1461D	Neutral	0.0
LRP5	O75197-1.2	V1461E	Neutral	0.0
LRP5	O75197-1.2	V1461F	Neutral	0.0
LRP5	O75197-1.2	V1461G	Neutral	0.001
LRP5	O75197-1.2	V1461H	Neutral	0.001
LRP5	O75197-1.2	V1461I	Neutral	0.0
LRP5	O75197-1.2	V1461K	Neutral	0.0
LRP5	O75197-1.2	V1461L	Neutral	0.0
LRP5	O75197-1.2	V1461M	Neutral	0.0
LRP5	O75197-1.2	V1461N	Neutral	0.0
LRP5	O75197-1.2	V1461P	Neutral	0.0
LRP5	O75197-1.2	V1461Q	Neutral	0.0
LRP5	O75197-1.2	V1461R	Neutral	0.0
LRP5	O75197-1.2	V1461S	Neutral	0.0
LRP5	O75197-1.2	V1461T	Neutral	0.0
LRP5	O75197-1.2	V1461W	Neutral	0.001
LRP5	O75197-1.2	V1461Y	Neutral	0.0
LRP5	O75197-1.2	S1462A	Neutral	0.005
LRP5	O75197-1.2	S1462C	Neutral	0.026
LRP5	O75197-1.2	S1462D	Neutral	0.011
LRP5	O75197-1.2	S1462E	Neutral	0.012
LRP5	O75197-1.2	S1462F	Neutral	0.035
LRP5	O75197-1.2	S1462G	Neutral	0.02
LRP5	O75197-1.2	S1462H	Neutral	0.051
LRP5	O75197-1.2	S1462I	Neutral	0.035
LRP5	O75197-1.2	S1462K	Neutral	0.009
LRP5	O75197-1.2	S1462L	Neutral	0.039
LRP5	O75197-1.2	S1462M	Neutral	0.02
LRP5	O75197-1.2	S1462N	Neutral	0.004
LRP5	O75197-1.2	S1462P	Neutral	0.033
LRP5	O75197-1.2	S1462Q	Neutral	0.017
LRP5	O75197-1.2	S1462R	Neutral	0.025
LRP5	O75197-1.2	S1462T	Neutral	0.005
LRP5	O75197-1.2	S1462V	Neutral	0.06
LRP5	O75197-1.2	S1462W	Neutral	0.066
LRP5	O75197-1.2	S1462Y	Neutral	0.071
LRP5	O75197-1.2	L1463A	Neutral	0.0
LRP5	O75197-1.2	L1463C	Neutral	0.0
LRP5	O75197-1.2	L1463D	Neutral	0.001
LRP5	O75197-1.2	L1463E	Neutral	0.001
LRP5	O75197-1.2	L1463F	Neutral	0.0
LRP5	O75197-1.2	L1463G	Neutral	0.002
LRP5	O75197-1.2	L1463H	Neutral	0.001
LRP5	O75197-1.2	L1463I	Neutral	0.0
LRP5	O75197-1.2	L1463K	Neutral	0.0
LRP5	O75197-1.2	L1463M	Neutral	0.0
LRP5	O75197-1.2	L1463N	Neutral	0.001
LRP5	O75197-1.2	L1463P	Neutral	0.002
LRP5	O75197-1.2	L1463Q	Neutral	0.0
LRP5	O75197-1.2	L1463R	Neutral	0.0
LRP5	O75197-1.2	L1463S	Neutral	0.0
LRP5	O75197-1.2	L1463T	Neutral	0.0
LRP5	O75197-1.2	L1463V	Neutral	0.0
LRP5	O75197-1.2	L1463W	Neutral	0.001
LRP5	O75197-1.2	L1463Y	Neutral	0.0
LRP5	O75197-1.2	M1464A	Neutral	0.012
LRP5	O75197-1.2	M1464C	Neutral	0.023
LRP5	O75197-1.2	M1464D	Neutral	0.044
LRP5	O75197-1.2	M1464E	Neutral	0.017
LRP5	O75197-1.2	M1464F	Neutral	0.006
LRP5	O75197-1.2	M1464G	Neutral	0.079
LRP5	O75197-1.2	M1464H	Neutral	0.034
LRP5	O75197-1.2	M1464I	Neutral	0.002
LRP5	O75197-1.2	M1464K	Neutral	0.004
LRP5	O75197-1.2	M1464L	Neutral	0.001
LRP5	O75197-1.2	M1464N	Neutral	0.017
LRP5	O75197-1.2	M1464P	Neutral	0.054
LRP5	O75197-1.2	M1464Q	Neutral	0.003
LRP5	O75197-1.2	M1464R	Neutral	0.004
LRP5	O75197-1.2	M1464S	Neutral	0.009
LRP5	O75197-1.2	M1464T	Neutral	0.012
LRP5	O75197-1.2	M1464V	Neutral	0.003
LRP5	O75197-1.2	M1464W	Neutral	0.012
LRP5	O75197-1.2	M1464Y	Neutral	0.023
LRP5	O75197-1.2	G1465A	Neutral	0.002
LRP5	O75197-1.2	G1465C	Neutral	0.023
LRP5	O75197-1.2	G1465D	Neutral	0.003
LRP5	O75197-1.2	G1465E	Neutral	0.01
LRP5	O75197-1.2	G1465F	Neutral	0.011
LRP5	O75197-1.2	G1465H	Neutral	0.016
LRP5	O75197-1.2	G1465I	Neutral	0.031
LRP5	O75197-1.2	G1465K	Neutral	0.007
LRP5	O75197-1.2	G1465L	Neutral	0.034
LRP5	O75197-1.2	G1465M	Neutral	0.017
LRP5	O75197-1.2	G1465N	Neutral	0.001
LRP5	O75197-1.2	G1465P	Neutral	0.01
LRP5	O75197-1.2	G1465Q	Neutral	0.014
LRP5	O75197-1.2	G1465R	Neutral	0.007
LRP5	O75197-1.2	G1465S	Neutral	0.002
LRP5	O75197-1.2	G1465T	Neutral	0.015
LRP5	O75197-1.2	G1465V	Neutral	0.018
LRP5	O75197-1.2	G1465W	Neutral	0.002
LRP5	O75197-1.2	G1465Y	Neutral	0.022
LRP5	O75197-1.2	G1466A	Neutral	0.007
LRP5	O75197-1.2	G1466C	Neutral	0.096
LRP5	O75197-1.2	G1466D	Neutral	0.014
LRP5	O75197-1.2	G1466E	Neutral	0.044
LRP5	O75197-1.2	G1466F	Neutral	0.045
LRP5	O75197-1.2	G1466H	Neutral	0.066
LRP5	O75197-1.2	G1466I	Neutral	0.127
LRP5	O75197-1.2	G1466K	Neutral	0.031
LRP5	O75197-1.2	G1466L	Neutral	0.138
LRP5	O75197-1.2	G1466M	Neutral	0.074
LRP5	O75197-1.2	G1466N	Neutral	0.005
LRP5	O75197-1.2	G1466P	Neutral	0.042
LRP5	O75197-1.2	G1466Q	Neutral	0.062
LRP5	O75197-1.2	G1466R	Neutral	0.03
LRP5	O75197-1.2	G1466S	Neutral	0.009
LRP5	O75197-1.2	G1466T	Neutral	0.062
LRP5	O75197-1.2	G1466V	Neutral	0.077
LRP5	O75197-1.2	G1466W	Neutral	0.01
LRP5	O75197-1.2	G1466Y	Neutral	0.09
LRP5	O75197-1.2	R1467A	Neutral	0.001
LRP5	O75197-1.2	R1467C	Neutral	0.003
LRP5	O75197-1.2	R1467D	Neutral	0.005
LRP5	O75197-1.2	R1467E	Neutral	0.001
LRP5	O75197-1.2	R1467F	Neutral	0.002
LRP5	O75197-1.2	R1467G	Neutral	0.002
LRP5	O75197-1.2	R1467H	Neutral	0.0
LRP5	O75197-1.2	R1467I	Neutral	0.002
LRP5	O75197-1.2	R1467K	Neutral	0.0
LRP5	O75197-1.2	R1467L	Neutral	0.001
LRP5	O75197-1.2	R1467M	Neutral	0.0
LRP5	O75197-1.2	R1467N	Neutral	0.0
LRP5	O75197-1.2	R1467P	Neutral	0.001
LRP5	O75197-1.2	R1467Q	Neutral	0.0
LRP5	O75197-1.2	R1467S	Neutral	0.001
LRP5	O75197-1.2	R1467T	Neutral	0.001
LRP5	O75197-1.2	R1467V	Neutral	0.003
LRP5	O75197-1.2	R1467W	Neutral	0.001
LRP5	O75197-1.2	R1467Y	Neutral	0.001
LRP5	O75197-1.2	G1468A	Neutral	0.0
LRP5	O75197-1.2	G1468C	Neutral	0.001
LRP5	O75197-1.2	G1468D	Neutral	0.0
LRP5	O75197-1.2	G1468E	Neutral	0.001
LRP5	O75197-1.2	G1468F	Neutral	0.001
LRP5	O75197-1.2	G1468H	Neutral	0.001
LRP5	O75197-1.2	G1468I	Neutral	0.002
LRP5	O75197-1.2	G1468K	Neutral	0.0
LRP5	O75197-1.2	G1468L	Neutral	0.002
LRP5	O75197-1.2	G1468M	Neutral	0.001
LRP5	O75197-1.2	G1468N	Neutral	0.0
LRP5	O75197-1.2	G1468P	Neutral	0.001
LRP5	O75197-1.2	G1468Q	Neutral	0.001
LRP5	O75197-1.2	G1468R	Neutral	0.0
LRP5	O75197-1.2	G1468S	Neutral	0.0
LRP5	O75197-1.2	G1468T	Neutral	0.001
LRP5	O75197-1.2	G1468V	Neutral	0.001
LRP5	O75197-1.2	G1468W	Neutral	0.0
LRP5	O75197-1.2	G1468Y	Neutral	0.001
LRP5	O75197-1.2	G1469A	Neutral	0.012
LRP5	O75197-1.2	G1469C	Neutral	0.15
LRP5	O75197-1.2	G1469D	Neutral	0.022
LRP5	O75197-1.2	G1469E	Neutral	0.071
LRP5	O75197-1.2	G1469F	Neutral	0.073
LRP5	O75197-1.2	G1469H	Neutral	0.105
LRP5	O75197-1.2	G1469I	Neutral	0.195
LRP5	O75197-1.2	G1469K	Neutral	0.051
LRP5	O75197-1.2	G1469L	Neutral	0.21
LRP5	O75197-1.2	G1469M	Neutral	0.117
LRP5	O75197-1.2	G1469N	Neutral	0.009
LRP5	O75197-1.2	G1469P	Neutral	0.068
LRP5	O75197-1.2	G1469Q	Neutral	0.099
LRP5	O75197-1.2	G1469R	Neutral	0.049
LRP5	O75197-1.2	G1469S	Neutral	0.015
LRP5	O75197-1.2	G1469T	Neutral	0.099
LRP5	O75197-1.2	G1469V	Neutral	0.122
LRP5	O75197-1.2	G1469W	Neutral	0.016
LRP5	O75197-1.2	G1469Y	Neutral	0.141
LRP5	O75197-1.2	V1470A	Neutral	0.0
LRP5	O75197-1.2	V1470C	Neutral	0.0
LRP5	O75197-1.2	V1470D	Neutral	0.0
LRP5	O75197-1.2	V1470E	Neutral	0.0
LRP5	O75197-1.2	V1470F	Neutral	0.0
LRP5	O75197-1.2	V1470G	Neutral	0.0
LRP5	O75197-1.2	V1470H	Neutral	0.0
LRP5	O75197-1.2	V1470I	Neutral	0.0
LRP5	O75197-1.2	V1470K	Neutral	0.0
LRP5	O75197-1.2	V1470L	Neutral	0.0
LRP5	O75197-1.2	V1470M	Neutral	0.0
LRP5	O75197-1.2	V1470N	Neutral	0.0
LRP5	O75197-1.2	V1470P	Neutral	0.0
LRP5	O75197-1.2	V1470Q	Neutral	0.0
LRP5	O75197-1.2	V1470R	Neutral	0.0
LRP5	O75197-1.2	V1470S	Neutral	0.0
LRP5	O75197-1.2	V1470T	Neutral	0.0
LRP5	O75197-1.2	V1470W	Neutral	0.0
LRP5	O75197-1.2	V1470Y	Neutral	0.0
LRP5	O75197-1.2	P1471A	Neutral	0.011
LRP5	O75197-1.2	P1471C	Neutral	0.106
LRP5	O75197-1.2	P1471D	Neutral	0.004
LRP5	O75197-1.2	P1471E	Neutral	0.005
LRP5	O75197-1.2	P1471F	Neutral	0.142
LRP5	O75197-1.2	P1471G	Neutral	0.024
LRP5	O75197-1.2	P1471H	Neutral	0.027
LRP5	O75197-1.2	P1471I	Neutral	0.052
LRP5	O75197-1.2	P1471K	Neutral	0.003
LRP5	O75197-1.2	P1471L	Neutral	0.056
LRP5	O75197-1.2	P1471M	Neutral	0.029
LRP5	O75197-1.2	P1471N	Neutral	0.015
LRP5	O75197-1.2	P1471Q	Neutral	0.007
LRP5	O75197-1.2	P1471R	Neutral	0.01
LRP5	O75197-1.2	P1471S	Neutral	0.008
LRP5	O75197-1.2	P1471T	Neutral	0.011
LRP5	O75197-1.2	P1471V	Neutral	0.03
LRP5	O75197-1.2	P1471W	Neutral	0.094
LRP5	O75197-1.2	P1471Y	Neutral	0.101
LRP5	O75197-1.2	L1472A	Neutral	0.001
LRP5	O75197-1.2	L1472C	Neutral	0.002
LRP5	O75197-1.2	L1472D	Neutral	0.009
LRP5	O75197-1.2	L1472E	Neutral	0.003
LRP5	O75197-1.2	L1472F	Neutral	0.001
LRP5	O75197-1.2	L1472G	Neutral	0.017
LRP5	O75197-1.2	L1472H	Neutral	0.007
LRP5	O75197-1.2	L1472I	Neutral	0.0
LRP5	O75197-1.2	L1472K	Neutral	0.001
LRP5	O75197-1.2	L1472M	Neutral	0.0
LRP5	O75197-1.2	L1472N	Neutral	0.003
LRP5	O75197-1.2	L1472P	Neutral	0.011
LRP5	O75197-1.2	L1472Q	Neutral	0.002
LRP5	O75197-1.2	L1472R	Neutral	0.001
LRP5	O75197-1.2	L1472S	Neutral	0.002
LRP5	O75197-1.2	L1472T	Neutral	0.001
LRP5	O75197-1.2	L1472V	Neutral	0.0
LRP5	O75197-1.2	L1472W	Neutral	0.005
LRP5	O75197-1.2	L1472Y	Neutral	0.002
LRP5	O75197-1.2	Y1473A	Neutral	0.278
LRP5	O75197-1.2	Y1473C	Neutral	0.411
LRP5	O75197-1.2	Y1473D	Neutral	0.317
LRP5	O75197-1.2	Y1473E	Neutral	0.15
LRP5	O75197-1.2	Y1473F	Neutral	0.001
LRP5	O75197-1.2	Y1473G	Neutral	0.463
LRP5	O75197-1.2	Y1473H	Neutral	0.004
LRP5	O75197-1.2	Y1473I	Neutral	0.105
LRP5	O75197-1.2	Y1473K	Neutral	0.118
LRP5	O75197-1.2	Y1473L	Neutral	0.113
LRP5	O75197-1.2	Y1473M	Neutral	0.163
LRP5	O75197-1.2	Y1473N	Neutral	0.152
LRP5	O75197-1.2	Y1473P	Pathogenic	0.637
LRP5	O75197-1.2	Y1473Q	Neutral	0.078
LRP5	O75197-1.2	Y1473R	Neutral	0.117
LRP5	O75197-1.2	Y1473S	Neutral	0.222
LRP5	O75197-1.2	Y1473T	Neutral	0.277
LRP5	O75197-1.2	Y1473V	Neutral	0.161
LRP5	O75197-1.2	Y1473W	Neutral	0.003
LRP5	O75197-1.2	D1474A	Neutral	0.103
LRP5	O75197-1.2	D1474C	Neutral	0.165
LRP5	O75197-1.2	D1474E	Neutral	0.003
LRP5	O75197-1.2	D1474F	Neutral	0.083
LRP5	O75197-1.2	D1474G	Neutral	0.046
LRP5	O75197-1.2	D1474H	Neutral	0.042
LRP5	O75197-1.2	D1474I	Neutral	0.083
LRP5	O75197-1.2	D1474K	Neutral	0.073
LRP5	O75197-1.2	D1474L	Neutral	0.232
LRP5	O75197-1.2	D1474M	Neutral	0.131
LRP5	O75197-1.2	D1474N	Neutral	0.009
LRP5	O75197-1.2	D1474P	Neutral	0.026
LRP5	O75197-1.2	D1474Q	Neutral	0.02
LRP5	O75197-1.2	D1474R	Neutral	0.188
LRP5	O75197-1.2	D1474S	Neutral	0.017
LRP5	O75197-1.2	D1474T	Neutral	0.039
LRP5	O75197-1.2	D1474V	Neutral	0.136
LRP5	O75197-1.2	D1474W	Neutral	0.148
LRP5	O75197-1.2	D1474Y	Neutral	0.158
LRP5	O75197-1.2	R1475A	Neutral	0.035
LRP5	O75197-1.2	R1475C	Neutral	0.159
LRP5	O75197-1.2	R1475D	Neutral	0.231
LRP5	O75197-1.2	R1475E	Neutral	0.029
LRP5	O75197-1.2	R1475F	Neutral	0.091
LRP5	O75197-1.2	R1475G	Neutral	0.124
LRP5	O75197-1.2	R1475H	Neutral	0.015
LRP5	O75197-1.2	R1475I	Neutral	0.088
LRP5	O75197-1.2	R1475K	Neutral	0.005
LRP5	O75197-1.2	R1475L	Neutral	0.034
LRP5	O75197-1.2	R1475M	Neutral	0.017
LRP5	O75197-1.2	R1475N	Neutral	0.027
LRP5	O75197-1.2	R1475P	Neutral	0.073
LRP5	O75197-1.2	R1475Q	Neutral	0.007
LRP5	O75197-1.2	R1475S	Neutral	0.047
LRP5	O75197-1.2	R1475T	Neutral	0.038
LRP5	O75197-1.2	R1475V	Neutral	0.137
LRP5	O75197-1.2	R1475W	Neutral	0.062
LRP5	O75197-1.2	R1475Y	Neutral	0.065
LRP5	O75197-1.2	N1476A	Neutral	0.002
LRP5	O75197-1.2	N1476C	Neutral	0.003
LRP5	O75197-1.2	N1476D	Neutral	0.0
LRP5	O75197-1.2	N1476E	Neutral	0.0
LRP5	O75197-1.2	N1476F	Neutral	0.002
LRP5	O75197-1.2	N1476G	Neutral	0.0
LRP5	O75197-1.2	N1476H	Neutral	0.0
LRP5	O75197-1.2	N1476I	Neutral	0.002
LRP5	O75197-1.2	N1476K	Neutral	0.0
LRP5	O75197-1.2	N1476L	Neutral	0.002
LRP5	O75197-1.2	N1476M	Neutral	0.001
LRP5	O75197-1.2	N1476P	Neutral	0.001
LRP5	O75197-1.2	N1476Q	Neutral	0.0
LRP5	O75197-1.2	N1476R	Neutral	0.0
LRP5	O75197-1.2	N1476S	Neutral	0.0
LRP5	O75197-1.2	N1476T	Neutral	0.0
LRP5	O75197-1.2	N1476V	Neutral	0.003
LRP5	O75197-1.2	N1476W	Neutral	0.003
LRP5	O75197-1.2	N1476Y	Neutral	0.001
LRP5	O75197-1.2	H1477A	Pathogenic	0.694
LRP5	O75197-1.2	H1477C	Pathogenic	0.796
LRP5	O75197-1.2	H1477D	Neutral	0.289
LRP5	O75197-1.2	H1477E	Neutral	0.134
LRP5	O75197-1.2	H1477F	Neutral	0.173
LRP5	O75197-1.2	H1477G	Pathogenic	0.696
LRP5	O75197-1.2	H1477I	Pathogenic	0.661
LRP5	O75197-1.2	H1477K	Neutral	0.253
LRP5	O75197-1.2	H1477L	Pathogenic	0.681
LRP5	O75197-1.2	H1477M	Pathogenic	0.517
LRP5	O75197-1.2	H1477N	Neutral	0.049
LRP5	O75197-1.2	H1477P	Pathogenic	0.62
LRP5	O75197-1.2	H1477Q	Neutral	0.184
LRP5	O75197-1.2	H1477R	Neutral	0.097
LRP5	O75197-1.2	H1477S	Neutral	0.431
LRP5	O75197-1.2	H1477T	Pathogenic	0.713
LRP5	O75197-1.2	H1477V	Pathogenic	0.765
LRP5	O75197-1.2	H1477W	Neutral	0.288
LRP5	O75197-1.2	H1477Y	Neutral	0.015
LRP5	O75197-1.2	V1478A	Neutral	0.006
LRP5	O75197-1.2	V1478C	Neutral	0.034
LRP5	O75197-1.2	V1478D	Neutral	0.064
LRP5	O75197-1.2	V1478E	Neutral	0.025
LRP5	O75197-1.2	V1478F	Neutral	0.025
LRP5	O75197-1.2	V1478G	Neutral	0.112
LRP5	O75197-1.2	V1478H	Neutral	0.132
LRP5	O75197-1.2	V1478I	Neutral	0.0
LRP5	O75197-1.2	V1478K	Neutral	0.018
LRP5	O75197-1.2	V1478L	Neutral	0.003
LRP5	O75197-1.2	V1478M	Neutral	0.005
LRP5	O75197-1.2	V1478N	Neutral	0.074
LRP5	O75197-1.2	V1478P	Neutral	0.078
LRP5	O75197-1.2	V1478Q	Neutral	0.036
LRP5	O75197-1.2	V1478R	Neutral	0.05
LRP5	O75197-1.2	V1478S	Neutral	0.04
LRP5	O75197-1.2	V1478T	Neutral	0.006
LRP5	O75197-1.2	V1478W	Neutral	0.129
LRP5	O75197-1.2	V1478Y	Neutral	0.032
LRP5	O75197-1.2	T1479A	Neutral	0.04
LRP5	O75197-1.2	T1479C	Neutral	0.066
LRP5	O75197-1.2	T1479D	Neutral	0.052
LRP5	O75197-1.2	T1479E	Neutral	0.057
LRP5	O75197-1.2	T1479F	Neutral	0.09
LRP5	O75197-1.2	T1479G	Neutral	0.236
LRP5	O75197-1.2	T1479H	Neutral	0.264
LRP5	O75197-1.2	T1479I	Neutral	0.032
LRP5	O75197-1.2	T1479K	Neutral	0.04
LRP5	O75197-1.2	T1479L	Neutral	0.035
LRP5	O75197-1.2	T1479M	Neutral	0.052
LRP5	O75197-1.2	T1479N	Neutral	0.02
LRP5	O75197-1.2	T1479P	Neutral	0.083
LRP5	O75197-1.2	T1479Q	Neutral	0.08
LRP5	O75197-1.2	T1479R	Neutral	0.039
LRP5	O75197-1.2	T1479S	Neutral	0.011
LRP5	O75197-1.2	T1479V	Neutral	0.018
LRP5	O75197-1.2	T1479W	Neutral	0.059
LRP5	O75197-1.2	T1479Y	Neutral	0.17
LRP5	O75197-1.2	G1480A	Neutral	0.028
LRP5	O75197-1.2	G1480C	Neutral	0.298
LRP5	O75197-1.2	G1480D	Neutral	0.052
LRP5	O75197-1.2	G1480E	Neutral	0.155
LRP5	O75197-1.2	G1480F	Neutral	0.16
LRP5	O75197-1.2	G1480H	Neutral	0.221
LRP5	O75197-1.2	G1480I	Neutral	0.368
LRP5	O75197-1.2	G1480K	Neutral	0.114
LRP5	O75197-1.2	G1480L	Neutral	0.39
LRP5	O75197-1.2	G1480M	Neutral	0.242
LRP5	O75197-1.2	G1480N	Neutral	0.02
LRP5	O75197-1.2	G1480P	Neutral	0.149
LRP5	O75197-1.2	G1480Q	Neutral	0.209
LRP5	O75197-1.2	G1480R	Neutral	0.11
LRP5	O75197-1.2	G1480S	Neutral	0.035
LRP5	O75197-1.2	G1480T	Neutral	0.209
LRP5	O75197-1.2	G1480V	Neutral	0.25
LRP5	O75197-1.2	G1480W	Neutral	0.038
LRP5	O75197-1.2	G1480Y	Neutral	0.284
LRP5	O75197-1.2	A1481C	Neutral	0.023
LRP5	O75197-1.2	A1481D	Neutral	0.13
LRP5	O75197-1.2	A1481E	Neutral	0.051
LRP5	O75197-1.2	A1481F	Neutral	0.088
LRP5	O75197-1.2	A1481G	Neutral	0.031
LRP5	O75197-1.2	A1481H	Neutral	0.242
LRP5	O75197-1.2	A1481I	Neutral	0.031
LRP5	O75197-1.2	A1481K	Neutral	0.036
LRP5	O75197-1.2	A1481L	Neutral	0.034
LRP5	O75197-1.2	A1481M	Neutral	0.051
LRP5	O75197-1.2	A1481N	Neutral	0.147
LRP5	O75197-1.2	A1481P	Neutral	0.082
LRP5	O75197-1.2	A1481Q	Neutral	0.072
LRP5	O75197-1.2	A1481R	Neutral	0.035
LRP5	O75197-1.2	A1481S	Neutral	0.01
LRP5	O75197-1.2	A1481T	Neutral	0.039
LRP5	O75197-1.2	A1481V	Neutral	0.018
LRP5	O75197-1.2	A1481W	Neutral	0.157
LRP5	O75197-1.2	A1481Y	Neutral	0.168
LRP5	O75197-1.2	S1482A	Neutral	0.024
LRP5	O75197-1.2	S1482C	Neutral	0.11
LRP5	O75197-1.2	S1482D	Neutral	0.049
LRP5	O75197-1.2	S1482E	Neutral	0.054
LRP5	O75197-1.2	S1482F	Neutral	0.144
LRP5	O75197-1.2	S1482G	Neutral	0.087
LRP5	O75197-1.2	S1482H	Neutral	0.2
LRP5	O75197-1.2	S1482I	Neutral	0.145
LRP5	O75197-1.2	S1482K	Neutral	0.038
LRP5	O75197-1.2	S1482L	Neutral	0.157
LRP5	O75197-1.2	S1482M	Neutral	0.085
LRP5	O75197-1.2	S1482N	Neutral	0.019
LRP5	O75197-1.2	S1482P	Neutral	0.134
LRP5	O75197-1.2	S1482Q	Neutral	0.076
LRP5	O75197-1.2	S1482R	Neutral	0.105
LRP5	O75197-1.2	S1482T	Neutral	0.025
LRP5	O75197-1.2	S1482V	Neutral	0.228
LRP5	O75197-1.2	S1482W	Neutral	0.245
LRP5	O75197-1.2	S1482Y	Neutral	0.259
LRP5	O75197-1.2	S1483A	Neutral	0.008
LRP5	O75197-1.2	S1483C	Neutral	0.037
LRP5	O75197-1.2	S1483D	Neutral	0.016
LRP5	O75197-1.2	S1483E	Neutral	0.017
LRP5	O75197-1.2	S1483F	Neutral	0.049
LRP5	O75197-1.2	S1483G	Neutral	0.029
LRP5	O75197-1.2	S1483H	Neutral	0.072
LRP5	O75197-1.2	S1483I	Neutral	0.05
LRP5	O75197-1.2	S1483K	Neutral	0.012
LRP5	O75197-1.2	S1483L	Neutral	0.054
LRP5	O75197-1.2	S1483M	Neutral	0.028
LRP5	O75197-1.2	S1483N	Neutral	0.006
LRP5	O75197-1.2	S1483P	Neutral	0.046
LRP5	O75197-1.2	S1483Q	Neutral	0.025
LRP5	O75197-1.2	S1483R	Neutral	0.035
LRP5	O75197-1.2	S1483T	Neutral	0.008
LRP5	O75197-1.2	S1483V	Neutral	0.083
LRP5	O75197-1.2	S1483W	Neutral	0.091
LRP5	O75197-1.2	S1483Y	Neutral	0.098
LRP5	O75197-1.2	S1484A	Neutral	0.007
LRP5	O75197-1.2	S1484C	Neutral	0.036
LRP5	O75197-1.2	S1484D	Neutral	0.015
LRP5	O75197-1.2	S1484E	Neutral	0.017
LRP5	O75197-1.2	S1484F	Neutral	0.048
LRP5	O75197-1.2	S1484G	Neutral	0.028
LRP5	O75197-1.2	S1484H	Neutral	0.07
LRP5	O75197-1.2	S1484I	Neutral	0.048
LRP5	O75197-1.2	S1484K	Neutral	0.012
LRP5	O75197-1.2	S1484L	Neutral	0.053
LRP5	O75197-1.2	S1484M	Neutral	0.027
LRP5	O75197-1.2	S1484N	Neutral	0.006
LRP5	O75197-1.2	S1484P	Neutral	0.044
LRP5	O75197-1.2	S1484Q	Neutral	0.024
LRP5	O75197-1.2	S1484R	Neutral	0.034
LRP5	O75197-1.2	S1484T	Neutral	0.007
LRP5	O75197-1.2	S1484V	Neutral	0.081
LRP5	O75197-1.2	S1484W	Neutral	0.088
LRP5	O75197-1.2	S1484Y	Neutral	0.095
LRP5	O75197-1.2	S1485A	Neutral	0.002
LRP5	O75197-1.2	S1485C	Neutral	0.008
LRP5	O75197-1.2	S1485D	Neutral	0.003
LRP5	O75197-1.2	S1485E	Neutral	0.004
LRP5	O75197-1.2	S1485F	Neutral	0.011
LRP5	O75197-1.2	S1485G	Neutral	0.006
LRP5	O75197-1.2	S1485H	Neutral	0.016
LRP5	O75197-1.2	S1485I	Neutral	0.011
LRP5	O75197-1.2	S1485K	Neutral	0.003
LRP5	O75197-1.2	S1485L	Neutral	0.012
LRP5	O75197-1.2	S1485M	Neutral	0.006
LRP5	O75197-1.2	S1485N	Neutral	0.001
LRP5	O75197-1.2	S1485P	Neutral	0.01
LRP5	O75197-1.2	S1485Q	Neutral	0.005
LRP5	O75197-1.2	S1485R	Neutral	0.007
LRP5	O75197-1.2	S1485T	Neutral	0.002
LRP5	O75197-1.2	S1485V	Neutral	0.018
LRP5	O75197-1.2	S1485W	Neutral	0.02
LRP5	O75197-1.2	S1485Y	Neutral	0.022
LRP5	O75197-1.2	S1486A	Neutral	0.001
LRP5	O75197-1.2	S1486C	Neutral	0.006
LRP5	O75197-1.2	S1486D	Neutral	0.002
LRP5	O75197-1.2	S1486E	Neutral	0.003
LRP5	O75197-1.2	S1486F	Neutral	0.008
LRP5	O75197-1.2	S1486G	Neutral	0.004
LRP5	O75197-1.2	S1486H	Neutral	0.012
LRP5	O75197-1.2	S1486I	Neutral	0.008
LRP5	O75197-1.2	S1486K	Neutral	0.002
LRP5	O75197-1.2	S1486L	Neutral	0.009
LRP5	O75197-1.2	S1486M	Neutral	0.004
LRP5	O75197-1.2	S1486N	Neutral	0.001
LRP5	O75197-1.2	S1486P	Neutral	0.007
LRP5	O75197-1.2	S1486Q	Neutral	0.004
LRP5	O75197-1.2	S1486R	Neutral	0.005
LRP5	O75197-1.2	S1486T	Neutral	0.001
LRP5	O75197-1.2	S1486V	Neutral	0.014
LRP5	O75197-1.2	S1486W	Neutral	0.015
LRP5	O75197-1.2	S1486Y	Neutral	0.016
LRP5	O75197-1.2	S1487A	Neutral	0.001
LRP5	O75197-1.2	S1487C	Neutral	0.003
LRP5	O75197-1.2	S1487D	Neutral	0.001
LRP5	O75197-1.2	S1487E	Neutral	0.002
LRP5	O75197-1.2	S1487F	Neutral	0.005
LRP5	O75197-1.2	S1487G	Neutral	0.003
LRP5	O75197-1.2	S1487H	Neutral	0.007
LRP5	O75197-1.2	S1487I	Neutral	0.005
LRP5	O75197-1.2	S1487K	Neutral	0.001
LRP5	O75197-1.2	S1487L	Neutral	0.005
LRP5	O75197-1.2	S1487M	Neutral	0.003
LRP5	O75197-1.2	S1487N	Neutral	0.001
LRP5	O75197-1.2	S1487P	Neutral	0.004
LRP5	O75197-1.2	S1487Q	Neutral	0.002
LRP5	O75197-1.2	S1487R	Neutral	0.003
LRP5	O75197-1.2	S1487T	Neutral	0.001
LRP5	O75197-1.2	S1487V	Neutral	0.008
LRP5	O75197-1.2	S1487W	Neutral	0.009
LRP5	O75197-1.2	S1487Y	Neutral	0.01
LRP5	O75197-1.2	S1488A	Neutral	0.002
LRP5	O75197-1.2	S1488C	Neutral	0.009
LRP5	O75197-1.2	S1488D	Neutral	0.004
LRP5	O75197-1.2	S1488E	Neutral	0.004
LRP5	O75197-1.2	S1488F	Neutral	0.012
LRP5	O75197-1.2	S1488G	Neutral	0.007
LRP5	O75197-1.2	S1488H	Neutral	0.018
LRP5	O75197-1.2	S1488I	Neutral	0.012
LRP5	O75197-1.2	S1488K	Neutral	0.003
LRP5	O75197-1.2	S1488L	Neutral	0.014
LRP5	O75197-1.2	S1488M	Neutral	0.007
LRP5	O75197-1.2	S1488N	Neutral	0.001
LRP5	O75197-1.2	S1488P	Neutral	0.011
LRP5	O75197-1.2	S1488Q	Neutral	0.006
LRP5	O75197-1.2	S1488R	Neutral	0.009
LRP5	O75197-1.2	S1488T	Neutral	0.002
LRP5	O75197-1.2	S1488V	Neutral	0.021
LRP5	O75197-1.2	S1488W	Neutral	0.024
LRP5	O75197-1.2	S1488Y	Neutral	0.025
LRP5	O75197-1.2	T1489A	Neutral	0.004
LRP5	O75197-1.2	T1489C	Neutral	0.007
LRP5	O75197-1.2	T1489D	Neutral	0.005
LRP5	O75197-1.2	T1489E	Neutral	0.006
LRP5	O75197-1.2	T1489F	Neutral	0.009
LRP5	O75197-1.2	T1489G	Neutral	0.029
LRP5	O75197-1.2	T1489H	Neutral	0.033
LRP5	O75197-1.2	T1489I	Neutral	0.003
LRP5	O75197-1.2	T1489K	Neutral	0.004
LRP5	O75197-1.2	T1489L	Neutral	0.003
LRP5	O75197-1.2	T1489M	Neutral	0.005
LRP5	O75197-1.2	T1489N	Neutral	0.002
LRP5	O75197-1.2	T1489P	Neutral	0.009
LRP5	O75197-1.2	T1489Q	Neutral	0.008
LRP5	O75197-1.2	T1489R	Neutral	0.004
LRP5	O75197-1.2	T1489S	Neutral	0.001
LRP5	O75197-1.2	T1489V	Neutral	0.002
LRP5	O75197-1.2	T1489W	Neutral	0.006
LRP5	O75197-1.2	T1489Y	Neutral	0.019
LRP5	O75197-1.2	K1490A	Neutral	0.003
LRP5	O75197-1.2	K1490C	Neutral	0.014
LRP5	O75197-1.2	K1490D	Neutral	0.007
LRP5	O75197-1.2	K1490E	Neutral	0.001
LRP5	O75197-1.2	K1490F	Neutral	0.007
LRP5	O75197-1.2	K1490G	Neutral	0.01
LRP5	O75197-1.2	K1490H	Neutral	0.003
LRP5	O75197-1.2	K1490I	Neutral	0.007
LRP5	O75197-1.2	K1490L	Neutral	0.003
LRP5	O75197-1.2	K1490M	Neutral	0.001
LRP5	O75197-1.2	K1490N	Neutral	0.002
LRP5	O75197-1.2	K1490P	Neutral	0.002
LRP5	O75197-1.2	K1490Q	Neutral	0.001
LRP5	O75197-1.2	K1490R	Neutral	0.0
LRP5	O75197-1.2	K1490S	Neutral	0.001
LRP5	O75197-1.2	K1490T	Neutral	0.003
LRP5	O75197-1.2	K1490V	Neutral	0.004
LRP5	O75197-1.2	K1490W	Neutral	0.005
LRP5	O75197-1.2	K1490Y	Neutral	0.005
LRP5	O75197-1.2	A1491C	Neutral	0.0
LRP5	O75197-1.2	A1491D	Neutral	0.001
LRP5	O75197-1.2	A1491E	Neutral	0.0
LRP5	O75197-1.2	A1491F	Neutral	0.001
LRP5	O75197-1.2	A1491G	Neutral	0.0
LRP5	O75197-1.2	A1491H	Neutral	0.002
LRP5	O75197-1.2	A1491I	Neutral	0.0
LRP5	O75197-1.2	A1491K	Neutral	0.0
LRP5	O75197-1.2	A1491L	Neutral	0.0
LRP5	O75197-1.2	A1491M	Neutral	0.0
LRP5	O75197-1.2	A1491N	Neutral	0.001
LRP5	O75197-1.2	A1491P	Neutral	0.001
LRP5	O75197-1.2	A1491Q	Neutral	0.001
LRP5	O75197-1.2	A1491R	Neutral	0.0
LRP5	O75197-1.2	A1491S	Neutral	0.0
LRP5	O75197-1.2	A1491T	Neutral	0.0
LRP5	O75197-1.2	A1491V	Neutral	0.0
LRP5	O75197-1.2	A1491W	Neutral	0.001
LRP5	O75197-1.2	A1491Y	Neutral	0.001
LRP5	O75197-1.2	T1492A	Neutral	0.002
LRP5	O75197-1.2	T1492C	Neutral	0.003
LRP5	O75197-1.2	T1492D	Neutral	0.002
LRP5	O75197-1.2	T1492E	Neutral	0.002
LRP5	O75197-1.2	T1492F	Neutral	0.004
LRP5	O75197-1.2	T1492G	Neutral	0.013
LRP5	O75197-1.2	T1492H	Neutral	0.015
LRP5	O75197-1.2	T1492I	Neutral	0.001
LRP5	O75197-1.2	T1492K	Neutral	0.002
LRP5	O75197-1.2	T1492L	Neutral	0.001
LRP5	O75197-1.2	T1492M	Neutral	0.002
LRP5	O75197-1.2	T1492N	Neutral	0.001
LRP5	O75197-1.2	T1492P	Neutral	0.004
LRP5	O75197-1.2	T1492Q	Neutral	0.004
LRP5	O75197-1.2	T1492R	Neutral	0.002
LRP5	O75197-1.2	T1492S	Neutral	0.0
LRP5	O75197-1.2	T1492V	Neutral	0.001
LRP5	O75197-1.2	T1492W	Neutral	0.003
LRP5	O75197-1.2	T1492Y	Neutral	0.008
LRP5	O75197-1.2	L1493A	Neutral	0.0
LRP5	O75197-1.2	L1493C	Neutral	0.0
LRP5	O75197-1.2	L1493D	Neutral	0.0
LRP5	O75197-1.2	L1493E	Neutral	0.0
LRP5	O75197-1.2	L1493F	Neutral	0.0
LRP5	O75197-1.2	L1493G	Neutral	0.0
LRP5	O75197-1.2	L1493H	Neutral	0.0
LRP5	O75197-1.2	L1493I	Neutral	0.0
LRP5	O75197-1.2	L1493K	Neutral	0.0
LRP5	O75197-1.2	L1493M	Neutral	0.0
LRP5	O75197-1.2	L1493N	Neutral	0.0
LRP5	O75197-1.2	L1493P	Neutral	0.0
LRP5	O75197-1.2	L1493Q	Neutral	0.0
LRP5	O75197-1.2	L1493R	Neutral	0.0
LRP5	O75197-1.2	L1493S	Neutral	0.0
LRP5	O75197-1.2	L1493T	Neutral	0.0
LRP5	O75197-1.2	L1493V	Neutral	0.0
LRP5	O75197-1.2	L1493W	Neutral	0.0
LRP5	O75197-1.2	L1493Y	Neutral	0.0
LRP5	O75197-1.2	Y1494A	Neutral	0.008
LRP5	O75197-1.2	Y1494C	Neutral	0.015
LRP5	O75197-1.2	Y1494D	Neutral	0.01
LRP5	O75197-1.2	Y1494E	Neutral	0.004
LRP5	O75197-1.2	Y1494F	Neutral	0.0
LRP5	O75197-1.2	Y1494G	Neutral	0.018
LRP5	O75197-1.2	Y1494H	Neutral	0.0
LRP5	O75197-1.2	Y1494I	Neutral	0.002
LRP5	O75197-1.2	Y1494K	Neutral	0.003
LRP5	O75197-1.2	Y1494L	Neutral	0.003
LRP5	O75197-1.2	Y1494M	Neutral	0.004
LRP5	O75197-1.2	Y1494N	Neutral	0.004
LRP5	O75197-1.2	Y1494P	Neutral	0.036
LRP5	O75197-1.2	Y1494Q	Neutral	0.002
LRP5	O75197-1.2	Y1494R	Neutral	0.003
LRP5	O75197-1.2	Y1494S	Neutral	0.006
LRP5	O75197-1.2	Y1494T	Neutral	0.008
LRP5	O75197-1.2	Y1494V	Neutral	0.004
LRP5	O75197-1.2	Y1494W	Neutral	0.0
LRP5	O75197-1.2	P1495A	Neutral	0.075
LRP5	O75197-1.2	P1495C	Neutral	0.47
LRP5	O75197-1.2	P1495D	Neutral	0.031
LRP5	O75197-1.2	P1495E	Neutral	0.034
LRP5	O75197-1.2	P1495F	Pathogenic	0.551
LRP5	O75197-1.2	P1495G	Neutral	0.154
LRP5	O75197-1.2	P1495H	Neutral	0.173
LRP5	O75197-1.2	P1495I	Neutral	0.288
LRP5	O75197-1.2	P1495K	Neutral	0.024
LRP5	O75197-1.2	P1495L	Neutral	0.307
LRP5	O75197-1.2	P1495M	Neutral	0.182
LRP5	O75197-1.2	P1495N	Neutral	0.101
LRP5	O75197-1.2	P1495Q	Neutral	0.048
LRP5	O75197-1.2	P1495R	Neutral	0.068
LRP5	O75197-1.2	P1495S	Neutral	0.057
LRP5	O75197-1.2	P1495T	Neutral	0.074
LRP5	O75197-1.2	P1495V	Neutral	0.188
LRP5	O75197-1.2	P1495W	Neutral	0.437
LRP5	O75197-1.2	P1495Y	Neutral	0.456
LRP5	O75197-1.2	P1496A	Neutral	0.001
LRP5	O75197-1.2	P1496C	Neutral	0.008
LRP5	O75197-1.2	P1496D	Neutral	0.0
LRP5	O75197-1.2	P1496E	Neutral	0.0
LRP5	O75197-1.2	P1496F	Neutral	0.011
LRP5	O75197-1.2	P1496G	Neutral	0.002
LRP5	O75197-1.2	P1496H	Neutral	0.002
LRP5	O75197-1.2	P1496I	Neutral	0.004
LRP5	O75197-1.2	P1496K	Neutral	0.0
LRP5	O75197-1.2	P1496L	Neutral	0.004
LRP5	O75197-1.2	P1496M	Neutral	0.002
LRP5	O75197-1.2	P1496N	Neutral	0.001
LRP5	O75197-1.2	P1496Q	Neutral	0.0
LRP5	O75197-1.2	P1496R	Neutral	0.001
LRP5	O75197-1.2	P1496S	Neutral	0.001
LRP5	O75197-1.2	P1496T	Neutral	0.001
LRP5	O75197-1.2	P1496V	Neutral	0.002
LRP5	O75197-1.2	P1496W	Neutral	0.007
LRP5	O75197-1.2	P1496Y	Neutral	0.007
LRP5	O75197-1.2	I1497A	Neutral	0.001
LRP5	O75197-1.2	I1497C	Neutral	0.001
LRP5	O75197-1.2	I1497D	Neutral	0.003
LRP5	O75197-1.2	I1497E	Neutral	0.003
LRP5	O75197-1.2	I1497F	Neutral	0.001
LRP5	O75197-1.2	I1497G	Neutral	0.015
LRP5	O75197-1.2	I1497H	Neutral	0.006
LRP5	O75197-1.2	I1497K	Neutral	0.002
LRP5	O75197-1.2	I1497L	Neutral	0.0
LRP5	O75197-1.2	I1497M	Neutral	0.0
LRP5	O75197-1.2	I1497N	Neutral	0.003
LRP5	O75197-1.2	I1497P	Neutral	0.01
LRP5	O75197-1.2	I1497Q	Neutral	0.004
LRP5	O75197-1.2	I1497R	Neutral	0.002
LRP5	O75197-1.2	I1497S	Neutral	0.002
LRP5	O75197-1.2	I1497T	Neutral	0.001
LRP5	O75197-1.2	I1497V	Neutral	0.0
LRP5	O75197-1.2	I1497W	Neutral	0.017
LRP5	O75197-1.2	I1497Y	Neutral	0.001
LRP5	O75197-1.2	L1498A	Neutral	0.062
LRP5	O75197-1.2	L1498C	Neutral	0.11
LRP5	O75197-1.2	L1498D	Neutral	0.424
LRP5	O75197-1.2	L1498E	Neutral	0.219
LRP5	O75197-1.2	L1498F	Neutral	0.07
LRP5	O75197-1.2	L1498G	Pathogenic	0.577
LRP5	O75197-1.2	L1498H	Neutral	0.361
LRP5	O75197-1.2	L1498I	Neutral	0.008
LRP5	O75197-1.2	L1498K	Neutral	0.063
LRP5	O75197-1.2	L1498M	Neutral	0.006
LRP5	O75197-1.2	L1498N	Neutral	0.221
LRP5	O75197-1.2	L1498P	Neutral	0.477
LRP5	O75197-1.2	L1498Q	Neutral	0.119
LRP5	O75197-1.2	L1498R	Neutral	0.061
LRP5	O75197-1.2	L1498S	Neutral	0.129
LRP5	O75197-1.2	L1498T	Neutral	0.062
LRP5	O75197-1.2	L1498V	Neutral	0.017
LRP5	O75197-1.2	L1498W	Neutral	0.305
LRP5	O75197-1.2	L1498Y	Neutral	0.112
LRP5	O75197-1.2	N1499A	Neutral	0.225
LRP5	O75197-1.2	N1499C	Neutral	0.333
LRP5	O75197-1.2	N1499D	Neutral	0.02
LRP5	O75197-1.2	N1499E	Neutral	0.066
LRP5	O75197-1.2	N1499F	Neutral	0.188
LRP5	O75197-1.2	N1499G	Neutral	0.039
LRP5	O75197-1.2	N1499H	Neutral	0.012
LRP5	O75197-1.2	N1499I	Neutral	0.189
LRP5	O75197-1.2	N1499K	Neutral	0.047
LRP5	O75197-1.2	N1499L	Neutral	0.203
LRP5	O75197-1.2	N1499M	Neutral	0.113
LRP5	O75197-1.2	N1499P	Neutral	0.173
LRP5	O75197-1.2	N1499Q	Neutral	0.049
LRP5	O75197-1.2	N1499R	Neutral	0.045
LRP5	O75197-1.2	N1499S	Neutral	0.014
LRP5	O75197-1.2	N1499T	Neutral	0.033
LRP5	O75197-1.2	N1499V	Neutral	0.288
LRP5	O75197-1.2	N1499W	Neutral	0.308
LRP5	O75197-1.2	N1499Y	Neutral	0.136
LRP5	O75197-1.2	P1500A	Pathogenic	0.958
LRP5	O75197-1.2	P1500C	Pathogenic	0.996
LRP5	O75197-1.2	P1500D	Pathogenic	0.9
LRP5	O75197-1.2	P1500E	Pathogenic	0.908
LRP5	O75197-1.2	P1500F	Pathogenic	0.997
LRP5	O75197-1.2	P1500G	Pathogenic	0.981
LRP5	O75197-1.2	P1500H	Pathogenic	0.983
LRP5	O75197-1.2	P1500I	Pathogenic	0.991
LRP5	O75197-1.2	P1500K	Pathogenic	0.873
LRP5	O75197-1.2	P1500L	Pathogenic	0.992
LRP5	O75197-1.2	P1500M	Pathogenic	0.984
LRP5	O75197-1.2	P1500N	Pathogenic	0.969
LRP5	O75197-1.2	P1500Q	Pathogenic	0.934
LRP5	O75197-1.2	P1500R	Pathogenic	0.953
LRP5	O75197-1.2	P1500S	Pathogenic	0.944
LRP5	O75197-1.2	P1500T	Pathogenic	0.957
LRP5	O75197-1.2	P1500V	Pathogenic	0.985
LRP5	O75197-1.2	P1500W	Pathogenic	0.995
LRP5	O75197-1.2	P1500Y	Pathogenic	0.996
LRP5	O75197-1.2	P1501A	Pathogenic	0.968
LRP5	O75197-1.2	P1501C	Pathogenic	0.997
LRP5	O75197-1.2	P1501D	Pathogenic	0.923
LRP5	O75197-1.2	P1501E	Pathogenic	0.929
LRP5	O75197-1.2	P1501F	Pathogenic	0.998
LRP5	O75197-1.2	P1501G	Pathogenic	0.985
LRP5	O75197-1.2	P1501H	Pathogenic	0.987
LRP5	O75197-1.2	P1501I	Pathogenic	0.993
LRP5	O75197-1.2	P1501K	Pathogenic	0.902
LRP5	O75197-1.2	P1501L	Pathogenic	0.994
LRP5	O75197-1.2	P1501M	Pathogenic	0.988
LRP5	O75197-1.2	P1501N	Pathogenic	0.977
LRP5	O75197-1.2	P1501Q	Pathogenic	0.95
LRP5	O75197-1.2	P1501R	Pathogenic	0.964
LRP5	O75197-1.2	P1501S	Pathogenic	0.957
LRP5	O75197-1.2	P1501T	Pathogenic	0.968
LRP5	O75197-1.2	P1501V	Pathogenic	0.989
LRP5	O75197-1.2	P1501W	Pathogenic	0.997
LRP5	O75197-1.2	P1501Y	Pathogenic	0.997
LRP5	O75197-1.2	P1502A	Pathogenic	0.977
LRP5	O75197-1.2	P1502C	Pathogenic	0.998
LRP5	O75197-1.2	P1502D	Pathogenic	0.944
LRP5	O75197-1.2	P1502E	Pathogenic	0.948
LRP5	O75197-1.2	P1502F	Pathogenic	0.998
LRP5	O75197-1.2	P1502G	Pathogenic	0.99
LRP5	O75197-1.2	P1502H	Pathogenic	0.991
LRP5	O75197-1.2	P1502I	Pathogenic	0.995
LRP5	O75197-1.2	P1502K	Pathogenic	0.928
LRP5	O75197-1.2	P1502L	Pathogenic	0.996
LRP5	O75197-1.2	P1502M	Pathogenic	0.991
LRP5	O75197-1.2	P1502N	Pathogenic	0.983
LRP5	O75197-1.2	P1502Q	Pathogenic	0.964
LRP5	O75197-1.2	P1502R	Pathogenic	0.974
LRP5	O75197-1.2	P1502S	Pathogenic	0.969
LRP5	O75197-1.2	P1502T	Pathogenic	0.977
LRP5	O75197-1.2	P1502V	Pathogenic	0.992
LRP5	O75197-1.2	P1502W	Pathogenic	0.998
LRP5	O75197-1.2	P1502Y	Pathogenic	0.998
LRP5	O75197-1.2	S1503A	Pathogenic	0.805
LRP5	O75197-1.2	S1503C	Pathogenic	0.954
LRP5	O75197-1.2	S1503D	Pathogenic	0.897
LRP5	O75197-1.2	S1503E	Pathogenic	0.905
LRP5	O75197-1.2	S1503F	Pathogenic	0.966
LRP5	O75197-1.2	S1503G	Pathogenic	0.941
LRP5	O75197-1.2	S1503H	Pathogenic	0.977
LRP5	O75197-1.2	S1503I	Pathogenic	0.966
LRP5	O75197-1.2	S1503K	Pathogenic	0.869
LRP5	O75197-1.2	S1503L	Pathogenic	0.969
LRP5	O75197-1.2	S1503M	Pathogenic	0.939
LRP5	O75197-1.2	S1503N	Pathogenic	0.767
LRP5	O75197-1.2	S1503P	Pathogenic	0.963
LRP5	O75197-1.2	S1503Q	Pathogenic	0.932
LRP5	O75197-1.2	S1503R	Pathogenic	0.951
LRP5	O75197-1.2	S1503T	Pathogenic	0.808
LRP5	O75197-1.2	S1503V	Pathogenic	0.98
LRP5	O75197-1.2	S1503W	Pathogenic	0.982
LRP5	O75197-1.2	S1503Y	Pathogenic	0.983
LRP5	O75197-1.2	P1504A	Pathogenic	0.975
LRP5	O75197-1.2	P1504C	Pathogenic	0.998
LRP5	O75197-1.2	P1504D	Pathogenic	0.939
LRP5	O75197-1.2	P1504E	Pathogenic	0.944
LRP5	O75197-1.2	P1504F	Pathogenic	0.998
LRP5	O75197-1.2	P1504G	Pathogenic	0.989
LRP5	O75197-1.2	P1504H	Pathogenic	0.99
LRP5	O75197-1.2	P1504I	Pathogenic	0.995
LRP5	O75197-1.2	P1504K	Pathogenic	0.922
LRP5	O75197-1.2	P1504L	Pathogenic	0.995
LRP5	O75197-1.2	P1504M	Pathogenic	0.991
LRP5	O75197-1.2	P1504N	Pathogenic	0.982
LRP5	O75197-1.2	P1504Q	Pathogenic	0.961
LRP5	O75197-1.2	P1504R	Pathogenic	0.972
LRP5	O75197-1.2	P1504S	Pathogenic	0.967
LRP5	O75197-1.2	P1504T	Pathogenic	0.975
LRP5	O75197-1.2	P1504V	Pathogenic	0.991
LRP5	O75197-1.2	P1504W	Pathogenic	0.997
LRP5	O75197-1.2	P1504Y	Pathogenic	0.998
LRP5	O75197-1.2	A1505C	Pathogenic	0.661
LRP5	O75197-1.2	A1505D	Pathogenic	0.926
LRP5	O75197-1.2	A1505E	Pathogenic	0.818
LRP5	O75197-1.2	A1505F	Pathogenic	0.89
LRP5	O75197-1.2	A1505G	Pathogenic	0.73
LRP5	O75197-1.2	A1505H	Pathogenic	0.964
LRP5	O75197-1.2	A1505I	Pathogenic	0.728
LRP5	O75197-1.2	A1505K	Pathogenic	0.759
LRP5	O75197-1.2	A1505L	Pathogenic	0.746
LRP5	O75197-1.2	A1505M	Pathogenic	0.817
LRP5	O75197-1.2	A1505N	Pathogenic	0.935
LRP5	O75197-1.2	A1505P	Pathogenic	0.882
LRP5	O75197-1.2	A1505Q	Pathogenic	0.866
LRP5	O75197-1.2	A1505R	Pathogenic	0.752
LRP5	O75197-1.2	A1505S	Neutral	0.468
LRP5	O75197-1.2	A1505T	Pathogenic	0.771
LRP5	O75197-1.2	A1505V	Pathogenic	0.605
LRP5	O75197-1.2	A1505W	Pathogenic	0.94
LRP5	O75197-1.2	A1505Y	Pathogenic	0.944
LRP5	O75197-1.2	T1506A	Pathogenic	0.925
LRP5	O75197-1.2	T1506C	Pathogenic	0.955
LRP5	O75197-1.2	T1506D	Pathogenic	0.942
LRP5	O75197-1.2	T1506E	Pathogenic	0.947
LRP5	O75197-1.2	T1506F	Pathogenic	0.967
LRP5	O75197-1.2	T1506G	Pathogenic	0.989
LRP5	O75197-1.2	T1506H	Pathogenic	0.991
LRP5	O75197-1.2	T1506I	Pathogenic	0.907
LRP5	O75197-1.2	T1506K	Pathogenic	0.926
LRP5	O75197-1.2	T1506L	Pathogenic	0.914
LRP5	O75197-1.2	T1506M	Pathogenic	0.942
LRP5	O75197-1.2	T1506N	Pathogenic	0.861
LRP5	O75197-1.2	T1506P	Pathogenic	0.964
LRP5	O75197-1.2	T1506Q	Pathogenic	0.963
LRP5	O75197-1.2	T1506R	Pathogenic	0.924
LRP5	O75197-1.2	T1506S	Pathogenic	0.767
LRP5	O75197-1.2	T1506V	Pathogenic	0.848
LRP5	O75197-1.2	T1506W	Pathogenic	0.949
LRP5	O75197-1.2	T1506Y	Pathogenic	0.984
LRP5	O75197-1.2	D1507A	Neutral	0.0
LRP5	O75197-1.2	D1507C	Neutral	0.0
LRP5	O75197-1.2	D1507E	Neutral	0.0
LRP5	O75197-1.2	D1507F	Neutral	0.0
LRP5	O75197-1.2	D1507G	Neutral	0.0
LRP5	O75197-1.2	D1507H	Neutral	0.0
LRP5	O75197-1.2	D1507I	Neutral	0.0
LRP5	O75197-1.2	D1507K	Neutral	0.0
LRP5	O75197-1.2	D1507L	Neutral	0.001
LRP5	O75197-1.2	D1507M	Neutral	0.0
LRP5	O75197-1.2	D1507N	Neutral	0.0
LRP5	O75197-1.2	D1507P	Neutral	0.0
LRP5	O75197-1.2	D1507Q	Neutral	0.0
LRP5	O75197-1.2	D1507R	Neutral	0.0
LRP5	O75197-1.2	D1507S	Neutral	0.0
LRP5	O75197-1.2	D1507T	Neutral	0.0
LRP5	O75197-1.2	D1507V	Neutral	0.0
LRP5	O75197-1.2	D1507W	Neutral	0.0
LRP5	O75197-1.2	D1507Y	Neutral	0.0
LRP5	O75197-1.2	P1508A	Neutral	0.0
LRP5	O75197-1.2	P1508C	Neutral	0.002
LRP5	O75197-1.2	P1508D	Neutral	0.0
LRP5	O75197-1.2	P1508E	Neutral	0.0
LRP5	O75197-1.2	P1508F	Neutral	0.002
LRP5	O75197-1.2	P1508G	Neutral	0.0
LRP5	O75197-1.2	P1508H	Neutral	0.0
LRP5	O75197-1.2	P1508I	Neutral	0.001
LRP5	O75197-1.2	P1508K	Neutral	0.0
LRP5	O75197-1.2	P1508L	Neutral	0.001
LRP5	O75197-1.2	P1508M	Neutral	0.0
LRP5	O75197-1.2	P1508N	Neutral	0.0
LRP5	O75197-1.2	P1508Q	Neutral	0.0
LRP5	O75197-1.2	P1508R	Neutral	0.0
LRP5	O75197-1.2	P1508S	Neutral	0.0
LRP5	O75197-1.2	P1508T	Neutral	0.0
LRP5	O75197-1.2	P1508V	Neutral	0.0
LRP5	O75197-1.2	P1508W	Neutral	0.002
LRP5	O75197-1.2	P1508Y	Neutral	0.002
LRP5	O75197-1.2	S1509A	Neutral	0.001
LRP5	O75197-1.2	S1509C	Neutral	0.003
LRP5	O75197-1.2	S1509D	Neutral	0.001
LRP5	O75197-1.2	S1509E	Neutral	0.001
LRP5	O75197-1.2	S1509F	Neutral	0.004
LRP5	O75197-1.2	S1509G	Neutral	0.002
LRP5	O75197-1.2	S1509H	Neutral	0.006
LRP5	O75197-1.2	S1509I	Neutral	0.004
LRP5	O75197-1.2	S1509K	Neutral	0.001
LRP5	O75197-1.2	S1509L	Neutral	0.004
LRP5	O75197-1.2	S1509M	Neutral	0.002
LRP5	O75197-1.2	S1509N	Neutral	0.0
LRP5	O75197-1.2	S1509P	Neutral	0.004
LRP5	O75197-1.2	S1509Q	Neutral	0.002
LRP5	O75197-1.2	S1509R	Neutral	0.003
LRP5	O75197-1.2	S1509T	Neutral	0.001
LRP5	O75197-1.2	S1509V	Neutral	0.007
LRP5	O75197-1.2	S1509W	Neutral	0.008
LRP5	O75197-1.2	S1509Y	Neutral	0.008
LRP5	O75197-1.2	L1510A	Neutral	0.0
LRP5	O75197-1.2	L1510C	Neutral	0.0
LRP5	O75197-1.2	L1510D	Neutral	0.0
LRP5	O75197-1.2	L1510E	Neutral	0.0
LRP5	O75197-1.2	L1510F	Neutral	0.0
LRP5	O75197-1.2	L1510G	Neutral	0.0
LRP5	O75197-1.2	L1510H	Neutral	0.0
LRP5	O75197-1.2	L1510I	Neutral	0.0
LRP5	O75197-1.2	L1510K	Neutral	0.0
LRP5	O75197-1.2	L1510M	Neutral	0.0
LRP5	O75197-1.2	L1510N	Neutral	0.0
LRP5	O75197-1.2	L1510P	Neutral	0.0
LRP5	O75197-1.2	L1510Q	Neutral	0.0
LRP5	O75197-1.2	L1510R	Neutral	0.0
LRP5	O75197-1.2	L1510S	Neutral	0.0
LRP5	O75197-1.2	L1510T	Neutral	0.0
LRP5	O75197-1.2	L1510V	Neutral	0.0
LRP5	O75197-1.2	L1510W	Neutral	0.0
LRP5	O75197-1.2	L1510Y	Neutral	0.0
LRP5	O75197-1.2	Y1511A	Neutral	0.009
LRP5	O75197-1.2	Y1511C	Neutral	0.016
LRP5	O75197-1.2	Y1511D	Neutral	0.011
LRP5	O75197-1.2	Y1511E	Neutral	0.004
LRP5	O75197-1.2	Y1511F	Neutral	0.0
LRP5	O75197-1.2	Y1511G	Neutral	0.02
LRP5	O75197-1.2	Y1511H	Neutral	0.0
LRP5	O75197-1.2	Y1511I	Neutral	0.003
LRP5	O75197-1.2	Y1511K	Neutral	0.003
LRP5	O75197-1.2	Y1511L	Neutral	0.003
LRP5	O75197-1.2	Y1511M	Neutral	0.004
LRP5	O75197-1.2	Y1511N	Neutral	0.004
LRP5	O75197-1.2	Y1511P	Neutral	0.039
LRP5	O75197-1.2	Y1511Q	Neutral	0.002
LRP5	O75197-1.2	Y1511R	Neutral	0.003
LRP5	O75197-1.2	Y1511S	Neutral	0.007
LRP5	O75197-1.2	Y1511T	Neutral	0.009
LRP5	O75197-1.2	Y1511V	Neutral	0.004
LRP5	O75197-1.2	Y1511W	Neutral	0.0
LRP5	O75197-1.2	N1512A	Neutral	0.001
LRP5	O75197-1.2	N1512C	Neutral	0.001
LRP5	O75197-1.2	N1512D	Neutral	0.0
LRP5	O75197-1.2	N1512E	Neutral	0.0
LRP5	O75197-1.2	N1512F	Neutral	0.001
LRP5	O75197-1.2	N1512G	Neutral	0.0
LRP5	O75197-1.2	N1512H	Neutral	0.0
LRP5	O75197-1.2	N1512I	Neutral	0.001
LRP5	O75197-1.2	N1512K	Neutral	0.0
LRP5	O75197-1.2	N1512L	Neutral	0.001
LRP5	O75197-1.2	N1512M	Neutral	0.0
LRP5	O75197-1.2	N1512P	Neutral	0.0
LRP5	O75197-1.2	N1512Q	Neutral	0.0
LRP5	O75197-1.2	N1512R	Neutral	0.0
LRP5	O75197-1.2	N1512S	Neutral	0.0
LRP5	O75197-1.2	N1512T	Neutral	0.0
LRP5	O75197-1.2	N1512V	Neutral	0.001
LRP5	O75197-1.2	N1512W	Neutral	0.001
LRP5	O75197-1.2	N1512Y	Neutral	0.0
LRP5	O75197-1.2	M1513A	Neutral	0.0
LRP5	O75197-1.2	M1513C	Neutral	0.0
LRP5	O75197-1.2	M1513D	Neutral	0.001
LRP5	O75197-1.2	M1513E	Neutral	0.0
LRP5	O75197-1.2	M1513F	Neutral	0.0
LRP5	O75197-1.2	M1513G	Neutral	0.001
LRP5	O75197-1.2	M1513H	Neutral	0.0
LRP5	O75197-1.2	M1513I	Neutral	0.0
LRP5	O75197-1.2	M1513K	Neutral	0.0
LRP5	O75197-1.2	M1513L	Neutral	0.0
LRP5	O75197-1.2	M1513N	Neutral	0.0
LRP5	O75197-1.2	M1513P	Neutral	0.001
LRP5	O75197-1.2	M1513Q	Neutral	0.0
LRP5	O75197-1.2	M1513R	Neutral	0.0
LRP5	O75197-1.2	M1513S	Neutral	0.0
LRP5	O75197-1.2	M1513T	Neutral	0.0
LRP5	O75197-1.2	M1513V	Neutral	0.0
LRP5	O75197-1.2	M1513W	Neutral	0.0
LRP5	O75197-1.2	M1513Y	Neutral	0.0
LRP5	O75197-1.2	D1514A	Neutral	0.0
LRP5	O75197-1.2	D1514C	Neutral	0.0
LRP5	O75197-1.2	D1514E	Neutral	0.0
LRP5	O75197-1.2	D1514F	Neutral	0.0
LRP5	O75197-1.2	D1514G	Neutral	0.0
LRP5	O75197-1.2	D1514H	Neutral	0.0
LRP5	O75197-1.2	D1514I	Neutral	0.0
LRP5	O75197-1.2	D1514K	Neutral	0.0
LRP5	O75197-1.2	D1514L	Neutral	0.0
LRP5	O75197-1.2	D1514M	Neutral	0.0
LRP5	O75197-1.2	D1514N	Neutral	0.0
LRP5	O75197-1.2	D1514P	Neutral	0.0
LRP5	O75197-1.2	D1514Q	Neutral	0.0
LRP5	O75197-1.2	D1514R	Neutral	0.0
LRP5	O75197-1.2	D1514S	Neutral	0.0
LRP5	O75197-1.2	D1514T	Neutral	0.0
LRP5	O75197-1.2	D1514V	Neutral	0.0
LRP5	O75197-1.2	D1514W	Neutral	0.0
LRP5	O75197-1.2	D1514Y	Neutral	0.0
LRP5	O75197-1.2	M1515A	Neutral	0.0
LRP5	O75197-1.2	M1515C	Neutral	0.0
LRP5	O75197-1.2	M1515D	Neutral	0.0
LRP5	O75197-1.2	M1515E	Neutral	0.0
LRP5	O75197-1.2	M1515F	Neutral	0.0
LRP5	O75197-1.2	M1515G	Neutral	0.001
LRP5	O75197-1.2	M1515H	Neutral	0.0
LRP5	O75197-1.2	M1515I	Neutral	0.0
LRP5	O75197-1.2	M1515K	Neutral	0.0
LRP5	O75197-1.2	M1515L	Neutral	0.0
LRP5	O75197-1.2	M1515N	Neutral	0.0
LRP5	O75197-1.2	M1515P	Neutral	0.001
LRP5	O75197-1.2	M1515Q	Neutral	0.0
LRP5	O75197-1.2	M1515R	Neutral	0.0
LRP5	O75197-1.2	M1515S	Neutral	0.0
LRP5	O75197-1.2	M1515T	Neutral	0.0
LRP5	O75197-1.2	M1515V	Neutral	0.0
LRP5	O75197-1.2	M1515W	Neutral	0.0
LRP5	O75197-1.2	M1515Y	Neutral	0.0
LRP5	O75197-1.2	F1516A	Neutral	0.007
LRP5	O75197-1.2	F1516C	Neutral	0.014
LRP5	O75197-1.2	F1516D	Neutral	0.009
LRP5	O75197-1.2	F1516E	Neutral	0.01
LRP5	O75197-1.2	F1516G	Neutral	0.016
LRP5	O75197-1.2	F1516H	Neutral	0.002
LRP5	O75197-1.2	F1516I	Neutral	0.003
LRP5	O75197-1.2	F1516K	Neutral	0.008
LRP5	O75197-1.2	F1516L	Neutral	0.003
LRP5	O75197-1.2	F1516M	Neutral	0.002
LRP5	O75197-1.2	F1516N	Neutral	0.01
LRP5	O75197-1.2	F1516P	Neutral	0.092
LRP5	O75197-1.2	F1516Q	Neutral	0.015
LRP5	O75197-1.2	F1516R	Neutral	0.007
LRP5	O75197-1.2	F1516S	Neutral	0.005
LRP5	O75197-1.2	F1516T	Neutral	0.007
LRP5	O75197-1.2	F1516V	Neutral	0.006
LRP5	O75197-1.2	F1516W	Neutral	0.001
LRP5	O75197-1.2	F1516Y	Neutral	0.0
LRP5	O75197-1.2	Y1517A	Neutral	0.016
LRP5	O75197-1.2	Y1517C	Neutral	0.028
LRP5	O75197-1.2	Y1517D	Neutral	0.019
LRP5	O75197-1.2	Y1517E	Neutral	0.007
LRP5	O75197-1.2	Y1517F	Neutral	0.0
LRP5	O75197-1.2	Y1517G	Neutral	0.035
LRP5	O75197-1.2	Y1517H	Neutral	0.0
LRP5	O75197-1.2	Y1517I	Neutral	0.005
LRP5	O75197-1.2	Y1517K	Neutral	0.006
LRP5	O75197-1.2	Y1517L	Neutral	0.005
LRP5	O75197-1.2	Y1517M	Neutral	0.008
LRP5	O75197-1.2	Y1517N	Neutral	0.007
LRP5	O75197-1.2	Y1517P	Neutral	0.068
LRP5	O75197-1.2	Y1517Q	Neutral	0.004
LRP5	O75197-1.2	Y1517R	Neutral	0.006
LRP5	O75197-1.2	Y1517S	Neutral	0.012
LRP5	O75197-1.2	Y1517T	Neutral	0.016
LRP5	O75197-1.2	Y1517V	Neutral	0.008
LRP5	O75197-1.2	Y1517W	Neutral	0.0
LRP5	O75197-1.2	S1518A	Neutral	0.0
LRP5	O75197-1.2	S1518C	Neutral	0.002
LRP5	O75197-1.2	S1518D	Neutral	0.001
LRP5	O75197-1.2	S1518E	Neutral	0.001
LRP5	O75197-1.2	S1518F	Neutral	0.003
LRP5	O75197-1.2	S1518G	Neutral	0.002
LRP5	O75197-1.2	S1518H	Neutral	0.005
LRP5	O75197-1.2	S1518I	Neutral	0.003
LRP5	O75197-1.2	S1518K	Neutral	0.001
LRP5	O75197-1.2	S1518L	Neutral	0.003
LRP5	O75197-1.2	S1518M	Neutral	0.002
LRP5	O75197-1.2	S1518N	Neutral	0.0
LRP5	O75197-1.2	S1518P	Neutral	0.003
LRP5	O75197-1.2	S1518Q	Neutral	0.002
LRP5	O75197-1.2	S1518R	Neutral	0.002
LRP5	O75197-1.2	S1518T	Neutral	0.0
LRP5	O75197-1.2	S1518V	Neutral	0.005
LRP5	O75197-1.2	S1518W	Neutral	0.006
LRP5	O75197-1.2	S1518Y	Neutral	0.006
LRP5	O75197-1.2	S1519A	Neutral	0.001
LRP5	O75197-1.2	S1519C	Neutral	0.003
LRP5	O75197-1.2	S1519D	Neutral	0.001
LRP5	O75197-1.2	S1519E	Neutral	0.001
LRP5	O75197-1.2	S1519F	Neutral	0.004
LRP5	O75197-1.2	S1519G	Neutral	0.002
LRP5	O75197-1.2	S1519H	Neutral	0.006
LRP5	O75197-1.2	S1519I	Neutral	0.004
LRP5	O75197-1.2	S1519K	Neutral	0.001
LRP5	O75197-1.2	S1519L	Neutral	0.004
LRP5	O75197-1.2	S1519M	Neutral	0.002
LRP5	O75197-1.2	S1519N	Neutral	0.0
LRP5	O75197-1.2	S1519P	Neutral	0.003
LRP5	O75197-1.2	S1519Q	Neutral	0.002
LRP5	O75197-1.2	S1519R	Neutral	0.003
LRP5	O75197-1.2	S1519T	Neutral	0.001
LRP5	O75197-1.2	S1519V	Neutral	0.007
LRP5	O75197-1.2	S1519W	Neutral	0.007
LRP5	O75197-1.2	S1519Y	Neutral	0.008
LRP5	O75197-1.2	N1520A	Neutral	0.003
LRP5	O75197-1.2	N1520C	Neutral	0.005
LRP5	O75197-1.2	N1520D	Neutral	0.0
LRP5	O75197-1.2	N1520E	Neutral	0.001
LRP5	O75197-1.2	N1520F	Neutral	0.002
LRP5	O75197-1.2	N1520G	Neutral	0.0
LRP5	O75197-1.2	N1520H	Neutral	0.0
LRP5	O75197-1.2	N1520I	Neutral	0.003
LRP5	O75197-1.2	N1520K	Neutral	0.001
LRP5	O75197-1.2	N1520L	Neutral	0.003
LRP5	O75197-1.2	N1520M	Neutral	0.001
LRP5	O75197-1.2	N1520P	Neutral	0.002
LRP5	O75197-1.2	N1520Q	Neutral	0.001
LRP5	O75197-1.2	N1520R	Neutral	0.001
LRP5	O75197-1.2	N1520S	Neutral	0.0
LRP5	O75197-1.2	N1520T	Neutral	0.0
LRP5	O75197-1.2	N1520V	Neutral	0.004
LRP5	O75197-1.2	N1520W	Neutral	0.005
LRP5	O75197-1.2	N1520Y	Neutral	0.002
LRP5	O75197-1.2	I1521A	Neutral	0.0
LRP5	O75197-1.2	I1521C	Neutral	0.0
LRP5	O75197-1.2	I1521D	Neutral	0.0
LRP5	O75197-1.2	I1521E	Neutral	0.0
LRP5	O75197-1.2	I1521F	Neutral	0.0
LRP5	O75197-1.2	I1521G	Neutral	0.001
LRP5	O75197-1.2	I1521H	Neutral	0.0
LRP5	O75197-1.2	I1521K	Neutral	0.0
LRP5	O75197-1.2	I1521L	Neutral	0.0
LRP5	O75197-1.2	I1521M	Neutral	0.0
LRP5	O75197-1.2	I1521N	Neutral	0.0
LRP5	O75197-1.2	I1521P	Neutral	0.001
LRP5	O75197-1.2	I1521Q	Neutral	0.0
LRP5	O75197-1.2	I1521R	Neutral	0.0
LRP5	O75197-1.2	I1521S	Neutral	0.0
LRP5	O75197-1.2	I1521T	Neutral	0.0
LRP5	O75197-1.2	I1521V	Neutral	0.0
LRP5	O75197-1.2	I1521W	Neutral	0.001
LRP5	O75197-1.2	I1521Y	Neutral	0.0
LRP5	O75197-1.2	P1522A	Neutral	0.019
LRP5	O75197-1.2	P1522C	Neutral	0.174
LRP5	O75197-1.2	P1522D	Neutral	0.008
LRP5	O75197-1.2	P1522E	Neutral	0.008
LRP5	O75197-1.2	P1522F	Neutral	0.226
LRP5	O75197-1.2	P1522G	Neutral	0.042
LRP5	O75197-1.2	P1522H	Neutral	0.048
LRP5	O75197-1.2	P1522I	Neutral	0.088
LRP5	O75197-1.2	P1522K	Neutral	0.006
LRP5	O75197-1.2	P1522L	Neutral	0.096
LRP5	O75197-1.2	P1522M	Neutral	0.05
LRP5	O75197-1.2	P1522N	Neutral	0.026
LRP5	O75197-1.2	P1522Q	Neutral	0.012
LRP5	O75197-1.2	P1522R	Neutral	0.017
LRP5	O75197-1.2	P1522S	Neutral	0.014
LRP5	O75197-1.2	P1522T	Neutral	0.019
LRP5	O75197-1.2	P1522V	Neutral	0.052
LRP5	O75197-1.2	P1522W	Neutral	0.156
LRP5	O75197-1.2	P1522Y	Neutral	0.167
LRP5	O75197-1.2	A1523C	Neutral	0.0
LRP5	O75197-1.2	A1523D	Neutral	0.0
LRP5	O75197-1.2	A1523E	Neutral	0.0
LRP5	O75197-1.2	A1523F	Neutral	0.0
LRP5	O75197-1.2	A1523G	Neutral	0.0
LRP5	O75197-1.2	A1523H	Neutral	0.0
LRP5	O75197-1.2	A1523I	Neutral	0.0
LRP5	O75197-1.2	A1523K	Neutral	0.0
LRP5	O75197-1.2	A1523L	Neutral	0.0
LRP5	O75197-1.2	A1523M	Neutral	0.0
LRP5	O75197-1.2	A1523N	Neutral	0.0
LRP5	O75197-1.2	A1523P	Neutral	0.0
LRP5	O75197-1.2	A1523Q	Neutral	0.0
LRP5	O75197-1.2	A1523R	Neutral	0.0
LRP5	O75197-1.2	A1523S	Neutral	0.0
LRP5	O75197-1.2	A1523T	Neutral	0.0
LRP5	O75197-1.2	A1523V	Neutral	0.0
LRP5	O75197-1.2	A1523W	Neutral	0.0
LRP5	O75197-1.2	A1523Y	Neutral	0.0
LRP5	O75197-1.2	T1524A	Neutral	0.001
LRP5	O75197-1.2	T1524C	Neutral	0.002
LRP5	O75197-1.2	T1524D	Neutral	0.002
LRP5	O75197-1.2	T1524E	Neutral	0.002
LRP5	O75197-1.2	T1524F	Neutral	0.003
LRP5	O75197-1.2	T1524G	Neutral	0.009
LRP5	O75197-1.2	T1524H	Neutral	0.011
LRP5	O75197-1.2	T1524I	Neutral	0.001
LRP5	O75197-1.2	T1524K	Neutral	0.001
LRP5	O75197-1.2	T1524L	Neutral	0.001
LRP5	O75197-1.2	T1524M	Neutral	0.002
LRP5	O75197-1.2	T1524N	Neutral	0.001
LRP5	O75197-1.2	T1524P	Neutral	0.003
LRP5	O75197-1.2	T1524Q	Neutral	0.003
LRP5	O75197-1.2	T1524R	Neutral	0.001
LRP5	O75197-1.2	T1524S	Neutral	0.0
LRP5	O75197-1.2	T1524V	Neutral	0.001
LRP5	O75197-1.2	T1524W	Neutral	0.002
LRP5	O75197-1.2	T1524Y	Neutral	0.006
LRP5	O75197-1.2	A1525C	Neutral	0.0
LRP5	O75197-1.2	A1525D	Neutral	0.0
LRP5	O75197-1.2	A1525E	Neutral	0.0
LRP5	O75197-1.2	A1525F	Neutral	0.0
LRP5	O75197-1.2	A1525G	Neutral	0.0
LRP5	O75197-1.2	A1525H	Neutral	0.0
LRP5	O75197-1.2	A1525I	Neutral	0.0
LRP5	O75197-1.2	A1525K	Neutral	0.0
LRP5	O75197-1.2	A1525L	Neutral	0.0
LRP5	O75197-1.2	A1525M	Neutral	0.0
LRP5	O75197-1.2	A1525N	Neutral	0.0
LRP5	O75197-1.2	A1525P	Neutral	0.0
LRP5	O75197-1.2	A1525Q	Neutral	0.0
LRP5	O75197-1.2	A1525R	Neutral	0.0
LRP5	O75197-1.2	A1525S	Neutral	0.0
LRP5	O75197-1.2	A1525T	Neutral	0.0
LRP5	O75197-1.2	A1525V	Neutral	0.0
LRP5	O75197-1.2	A1525W	Neutral	0.0
LRP5	O75197-1.2	A1525Y	Neutral	0.0
LRP5	O75197-1.2	R1526A	Neutral	0.006
LRP5	O75197-1.2	R1526C	Neutral	0.03
LRP5	O75197-1.2	R1526D	Neutral	0.047
LRP5	O75197-1.2	R1526E	Neutral	0.005
LRP5	O75197-1.2	R1526F	Neutral	0.016
LRP5	O75197-1.2	R1526G	Neutral	0.023
LRP5	O75197-1.2	R1526H	Neutral	0.002
LRP5	O75197-1.2	R1526I	Neutral	0.016
LRP5	O75197-1.2	R1526K	Neutral	0.001
LRP5	O75197-1.2	R1526L	Neutral	0.006
LRP5	O75197-1.2	R1526M	Neutral	0.003
LRP5	O75197-1.2	R1526N	Neutral	0.005
LRP5	O75197-1.2	R1526P	Neutral	0.013
LRP5	O75197-1.2	R1526Q	Neutral	0.001
LRP5	O75197-1.2	R1526S	Neutral	0.008
LRP5	O75197-1.2	R1526T	Neutral	0.006
LRP5	O75197-1.2	R1526V	Neutral	0.025
LRP5	O75197-1.2	R1526W	Neutral	0.011
LRP5	O75197-1.2	R1526Y	Neutral	0.011
LRP5	O75197-1.2	P1527A	Neutral	0.0
LRP5	O75197-1.2	P1527C	Neutral	0.005
LRP5	O75197-1.2	P1527D	Neutral	0.0
LRP5	O75197-1.2	P1527E	Neutral	0.0
LRP5	O75197-1.2	P1527F	Neutral	0.007
LRP5	O75197-1.2	P1527G	Neutral	0.001
LRP5	O75197-1.2	P1527H	Neutral	0.001
LRP5	O75197-1.2	P1527I	Neutral	0.002
LRP5	O75197-1.2	P1527K	Neutral	0.0
LRP5	O75197-1.2	P1527L	Neutral	0.003
LRP5	O75197-1.2	P1527M	Neutral	0.001
LRP5	O75197-1.2	P1527N	Neutral	0.001
LRP5	O75197-1.2	P1527Q	Neutral	0.0
LRP5	O75197-1.2	P1527R	Neutral	0.0
LRP5	O75197-1.2	P1527S	Neutral	0.0
LRP5	O75197-1.2	P1527T	Neutral	0.0
LRP5	O75197-1.2	P1527V	Neutral	0.001
LRP5	O75197-1.2	P1527W	Neutral	0.005
LRP5	O75197-1.2	P1527Y	Neutral	0.005
LRP5	O75197-1.2	Y1528A	Neutral	0.056
LRP5	O75197-1.2	Y1528C	Neutral	0.097
LRP5	O75197-1.2	Y1528D	Neutral	0.067
LRP5	O75197-1.2	Y1528E	Neutral	0.026
LRP5	O75197-1.2	Y1528F	Neutral	0.0
LRP5	O75197-1.2	Y1528G	Neutral	0.117
LRP5	O75197-1.2	Y1528H	Neutral	0.001
LRP5	O75197-1.2	Y1528I	Neutral	0.018
LRP5	O75197-1.2	Y1528K	Neutral	0.02
LRP5	O75197-1.2	Y1528L	Neutral	0.019
LRP5	O75197-1.2	Y1528M	Neutral	0.029
LRP5	O75197-1.2	Y1528N	Neutral	0.027
LRP5	O75197-1.2	Y1528P	Neutral	0.212
LRP5	O75197-1.2	Y1528Q	Neutral	0.013
LRP5	O75197-1.2	Y1528R	Neutral	0.02
LRP5	O75197-1.2	Y1528S	Neutral	0.042
LRP5	O75197-1.2	Y1528T	Neutral	0.056
LRP5	O75197-1.2	Y1528V	Neutral	0.029
LRP5	O75197-1.2	Y1528W	Neutral	0.0
LRP5	O75197-1.2	R1529A	Neutral	0.012
LRP5	O75197-1.2	R1529C	Neutral	0.062
LRP5	O75197-1.2	R1529D	Neutral	0.095
LRP5	O75197-1.2	R1529E	Neutral	0.01
LRP5	O75197-1.2	R1529F	Neutral	0.034
LRP5	O75197-1.2	R1529G	Neutral	0.047
LRP5	O75197-1.2	R1529H	Neutral	0.005
LRP5	O75197-1.2	R1529I	Neutral	0.033
LRP5	O75197-1.2	R1529K	Neutral	0.002
LRP5	O75197-1.2	R1529L	Neutral	0.012
LRP5	O75197-1.2	R1529M	Neutral	0.006
LRP5	O75197-1.2	R1529N	Neutral	0.01
LRP5	O75197-1.2	R1529P	Neutral	0.027
LRP5	O75197-1.2	R1529Q	Neutral	0.002
LRP5	O75197-1.2	R1529S	Neutral	0.017
LRP5	O75197-1.2	R1529T	Neutral	0.014
LRP5	O75197-1.2	R1529V	Neutral	0.052
LRP5	O75197-1.2	R1529W	Neutral	0.022
LRP5	O75197-1.2	R1529Y	Neutral	0.024
LRP5	O75197-1.2	P1530A	Neutral	0.032
LRP5	O75197-1.2	P1530C	Neutral	0.263
LRP5	O75197-1.2	P1530D	Neutral	0.013
LRP5	O75197-1.2	P1530E	Neutral	0.014
LRP5	O75197-1.2	P1530F	Neutral	0.331
LRP5	O75197-1.2	P1530G	Neutral	0.069
LRP5	O75197-1.2	P1530H	Neutral	0.078
LRP5	O75197-1.2	P1530I	Neutral	0.14
LRP5	O75197-1.2	P1530K	Neutral	0.01
LRP5	O75197-1.2	P1530L	Neutral	0.152
LRP5	O75197-1.2	P1530M	Neutral	0.082
LRP5	O75197-1.2	P1530N	Neutral	0.044
LRP5	O75197-1.2	P1530Q	Neutral	0.02
LRP5	O75197-1.2	P1530R	Neutral	0.028
LRP5	O75197-1.2	P1530S	Neutral	0.024
LRP5	O75197-1.2	P1530T	Neutral	0.031
LRP5	O75197-1.2	P1530V	Neutral	0.086
LRP5	O75197-1.2	P1530W	Neutral	0.238
LRP5	O75197-1.2	P1530Y	Neutral	0.253
LRP5	O75197-1.2	Y1531A	Neutral	0.072
LRP5	O75197-1.2	Y1531C	Neutral	0.123
LRP5	O75197-1.2	Y1531D	Neutral	0.085
LRP5	O75197-1.2	Y1531E	Neutral	0.034
LRP5	O75197-1.2	Y1531F	Neutral	0.0
LRP5	O75197-1.2	Y1531G	Neutral	0.148
LRP5	O75197-1.2	Y1531H	Neutral	0.001
LRP5	O75197-1.2	Y1531I	Neutral	0.023
LRP5	O75197-1.2	Y1531K	Neutral	0.026
LRP5	O75197-1.2	Y1531L	Neutral	0.025
LRP5	O75197-1.2	Y1531M	Neutral	0.038
LRP5	O75197-1.2	Y1531N	Neutral	0.035
LRP5	O75197-1.2	Y1531P	Neutral	0.261
LRP5	O75197-1.2	Y1531Q	Neutral	0.017
LRP5	O75197-1.2	Y1531R	Neutral	0.026
LRP5	O75197-1.2	Y1531S	Neutral	0.054
LRP5	O75197-1.2	Y1531T	Neutral	0.072
LRP5	O75197-1.2	Y1531V	Neutral	0.037
LRP5	O75197-1.2	Y1531W	Neutral	0.001
LRP5	O75197-1.2	I1532A	Neutral	0.0
LRP5	O75197-1.2	I1532C	Neutral	0.0
LRP5	O75197-1.2	I1532D	Neutral	0.0
LRP5	O75197-1.2	I1532E	Neutral	0.0
LRP5	O75197-1.2	I1532F	Neutral	0.0
LRP5	O75197-1.2	I1532G	Neutral	0.0
LRP5	O75197-1.2	I1532H	Neutral	0.0
LRP5	O75197-1.2	I1532K	Neutral	0.0
LRP5	O75197-1.2	I1532L	Neutral	0.0
LRP5	O75197-1.2	I1532M	Neutral	0.0
LRP5	O75197-1.2	I1532N	Neutral	0.0
LRP5	O75197-1.2	I1532P	Neutral	0.0
LRP5	O75197-1.2	I1532Q	Neutral	0.0
LRP5	O75197-1.2	I1532R	Neutral	0.0
LRP5	O75197-1.2	I1532S	Neutral	0.0
LRP5	O75197-1.2	I1532T	Neutral	0.0
LRP5	O75197-1.2	I1532V	Neutral	0.0
LRP5	O75197-1.2	I1532W	Neutral	0.0
LRP5	O75197-1.2	I1532Y	Neutral	0.0
LRP5	O75197-1.2	I1533A	Neutral	0.0
LRP5	O75197-1.2	I1533C	Neutral	0.0
LRP5	O75197-1.2	I1533D	Neutral	0.0
LRP5	O75197-1.2	I1533E	Neutral	0.0
LRP5	O75197-1.2	I1533F	Neutral	0.0
LRP5	O75197-1.2	I1533G	Neutral	0.001
LRP5	O75197-1.2	I1533H	Neutral	0.0
LRP5	O75197-1.2	I1533K	Neutral	0.0
LRP5	O75197-1.2	I1533L	Neutral	0.0
LRP5	O75197-1.2	I1533M	Neutral	0.0
LRP5	O75197-1.2	I1533N	Neutral	0.0
LRP5	O75197-1.2	I1533P	Neutral	0.001
LRP5	O75197-1.2	I1533Q	Neutral	0.0
LRP5	O75197-1.2	I1533R	Neutral	0.0
LRP5	O75197-1.2	I1533S	Neutral	0.0
LRP5	O75197-1.2	I1533T	Neutral	0.0
LRP5	O75197-1.2	I1533V	Neutral	0.0
LRP5	O75197-1.2	I1533W	Neutral	0.001
LRP5	O75197-1.2	I1533Y	Neutral	0.0
LRP5	O75197-1.2	R1534A	Neutral	0.003
LRP5	O75197-1.2	R1534C	Neutral	0.018
LRP5	O75197-1.2	R1534D	Neutral	0.028
LRP5	O75197-1.2	R1534E	Neutral	0.003
LRP5	O75197-1.2	R1534F	Neutral	0.009
LRP5	O75197-1.2	R1534G	Neutral	0.013
LRP5	O75197-1.2	R1534H	Neutral	0.001
LRP5	O75197-1.2	R1534I	Neutral	0.009
LRP5	O75197-1.2	R1534K	Neutral	0.0
LRP5	O75197-1.2	R1534L	Neutral	0.003
LRP5	O75197-1.2	R1534M	Neutral	0.002
LRP5	O75197-1.2	R1534N	Neutral	0.003
LRP5	O75197-1.2	R1534P	Neutral	0.007
LRP5	O75197-1.2	R1534Q	Neutral	0.001
LRP5	O75197-1.2	R1534S	Neutral	0.005
LRP5	O75197-1.2	R1534T	Neutral	0.004
LRP5	O75197-1.2	R1534V	Neutral	0.015
LRP5	O75197-1.2	R1534W	Neutral	0.006
LRP5	O75197-1.2	R1534Y	Neutral	0.007
LRP5	O75197-1.2	G1535A	Neutral	0.0
LRP5	O75197-1.2	G1535C	Neutral	0.001
LRP5	O75197-1.2	G1535D	Neutral	0.0
LRP5	O75197-1.2	G1535E	Neutral	0.0
LRP5	O75197-1.2	G1535F	Neutral	0.0
LRP5	O75197-1.2	G1535H	Neutral	0.001
LRP5	O75197-1.2	G1535I	Neutral	0.001
LRP5	O75197-1.2	G1535K	Neutral	0.0
LRP5	O75197-1.2	G1535L	Neutral	0.001
LRP5	O75197-1.2	G1535M	Neutral	0.001
LRP5	O75197-1.2	G1535N	Neutral	0.0
LRP5	O75197-1.2	G1535P	Neutral	0.0
LRP5	O75197-1.2	G1535Q	Neutral	0.001
LRP5	O75197-1.2	G1535R	Neutral	0.0
LRP5	O75197-1.2	G1535S	Neutral	0.0
LRP5	O75197-1.2	G1535T	Neutral	0.001
LRP5	O75197-1.2	G1535V	Neutral	0.001
LRP5	O75197-1.2	G1535W	Neutral	0.0
LRP5	O75197-1.2	G1535Y	Neutral	0.001
LRP5	O75197-1.2	M1536A	Neutral	0.0
LRP5	O75197-1.2	M1536C	Neutral	0.0
LRP5	O75197-1.2	M1536D	Neutral	0.0
LRP5	O75197-1.2	M1536E	Neutral	0.0
LRP5	O75197-1.2	M1536F	Neutral	0.0
LRP5	O75197-1.2	M1536G	Neutral	0.0
LRP5	O75197-1.2	M1536H	Neutral	0.0
LRP5	O75197-1.2	M1536I	Neutral	0.0
LRP5	O75197-1.2	M1536K	Neutral	0.0
LRP5	O75197-1.2	M1536L	Neutral	0.0
LRP5	O75197-1.2	M1536N	Neutral	0.0
LRP5	O75197-1.2	M1536P	Neutral	0.0
LRP5	O75197-1.2	M1536Q	Neutral	0.0
LRP5	O75197-1.2	M1536R	Neutral	0.0
LRP5	O75197-1.2	M1536S	Neutral	0.0
LRP5	O75197-1.2	M1536T	Neutral	0.0
LRP5	O75197-1.2	M1536V	Neutral	0.0
LRP5	O75197-1.2	M1536W	Neutral	0.0
LRP5	O75197-1.2	M1536Y	Neutral	0.0
LRP5	O75197-1.2	A1537C	Neutral	0.001
LRP5	O75197-1.2	A1537D	Neutral	0.006
LRP5	O75197-1.2	A1537E	Neutral	0.002
LRP5	O75197-1.2	A1537F	Neutral	0.004
LRP5	O75197-1.2	A1537G	Neutral	0.001
LRP5	O75197-1.2	A1537H	Neutral	0.012
LRP5	O75197-1.2	A1537I	Neutral	0.001
LRP5	O75197-1.2	A1537K	Neutral	0.001
LRP5	O75197-1.2	A1537L	Neutral	0.001
LRP5	O75197-1.2	A1537M	Neutral	0.002
LRP5	O75197-1.2	A1537N	Neutral	0.007
LRP5	O75197-1.2	A1537P	Neutral	0.003
LRP5	O75197-1.2	A1537Q	Neutral	0.003
LRP5	O75197-1.2	A1537R	Neutral	0.001
LRP5	O75197-1.2	A1537S	Neutral	0.0
LRP5	O75197-1.2	A1537T	Neutral	0.002
LRP5	O75197-1.2	A1537V	Neutral	0.001
LRP5	O75197-1.2	A1537W	Neutral	0.007
LRP5	O75197-1.2	A1537Y	Neutral	0.008
LRP5	O75197-1.2	P1538A	Pathogenic	0.992
LRP5	O75197-1.2	P1538C	Pathogenic	0.999
LRP5	O75197-1.2	P1538D	Pathogenic	0.979
LRP5	O75197-1.2	P1538E	Pathogenic	0.981
LRP5	O75197-1.2	P1538F	Pathogenic	0.999
LRP5	O75197-1.2	P1538G	Pathogenic	0.996
LRP5	O75197-1.2	P1538H	Pathogenic	0.997
LRP5	O75197-1.2	P1538I	Pathogenic	0.998
LRP5	O75197-1.2	P1538K	Pathogenic	0.973
LRP5	O75197-1.2	P1538L	Pathogenic	0.998
LRP5	O75197-1.2	P1538M	Pathogenic	0.997
LRP5	O75197-1.2	P1538N	Pathogenic	0.994
LRP5	O75197-1.2	P1538Q	Pathogenic	0.987
LRP5	O75197-1.2	P1538R	Pathogenic	0.991
LRP5	O75197-1.2	P1538S	Pathogenic	0.989
LRP5	O75197-1.2	P1538T	Pathogenic	0.992
LRP5	O75197-1.2	P1538V	Pathogenic	0.997
LRP5	O75197-1.2	P1538W	Pathogenic	0.999
LRP5	O75197-1.2	P1538Y	Pathogenic	0.999
LRP5	O75197-1.2	P1539A	Pathogenic	0.965
LRP5	O75197-1.2	P1539C	Pathogenic	0.997
LRP5	O75197-1.2	P1539D	Pathogenic	0.916
LRP5	O75197-1.2	P1539E	Pathogenic	0.923
LRP5	O75197-1.2	P1539F	Pathogenic	0.998
LRP5	O75197-1.2	P1539G	Pathogenic	0.984
LRP5	O75197-1.2	P1539H	Pathogenic	0.986
LRP5	O75197-1.2	P1539I	Pathogenic	0.993
LRP5	O75197-1.2	P1539K	Pathogenic	0.893
LRP5	O75197-1.2	P1539L	Pathogenic	0.993
LRP5	O75197-1.2	P1539M	Pathogenic	0.987
LRP5	O75197-1.2	P1539N	Pathogenic	0.974
LRP5	O75197-1.2	P1539Q	Pathogenic	0.945
LRP5	O75197-1.2	P1539R	Pathogenic	0.961
LRP5	O75197-1.2	P1539S	Pathogenic	0.953
LRP5	O75197-1.2	P1539T	Pathogenic	0.965
LRP5	O75197-1.2	P1539V	Pathogenic	0.987
LRP5	O75197-1.2	P1539W	Pathogenic	0.996
LRP5	O75197-1.2	P1539Y	Pathogenic	0.996
LRP5	O75197-1.2	T1540A	Pathogenic	0.619
LRP5	O75197-1.2	T1540C	Pathogenic	0.736
LRP5	O75197-1.2	T1540D	Pathogenic	0.683
LRP5	O75197-1.2	T1540E	Pathogenic	0.703
LRP5	O75197-1.2	T1540F	Pathogenic	0.796
LRP5	O75197-1.2	T1540G	Pathogenic	0.924
LRP5	O75197-1.2	T1540H	Pathogenic	0.934
LRP5	O75197-1.2	T1540I	Pathogenic	0.563
LRP5	O75197-1.2	T1540K	Pathogenic	0.624
LRP5	O75197-1.2	T1540L	Pathogenic	0.585
LRP5	O75197-1.2	T1540M	Pathogenic	0.682
LRP5	O75197-1.2	T1540N	Neutral	0.451
LRP5	O75197-1.2	T1540P	Pathogenic	0.781
LRP5	O75197-1.2	T1540Q	Pathogenic	0.773
LRP5	O75197-1.2	T1540R	Pathogenic	0.616
LRP5	O75197-1.2	T1540S	Neutral	0.303
LRP5	O75197-1.2	T1540V	Neutral	0.425
LRP5	O75197-1.2	T1540W	Pathogenic	0.712
LRP5	O75197-1.2	T1540Y	Pathogenic	0.89
LRP5	O75197-1.2	T1541A	Pathogenic	0.978
LRP5	O75197-1.2	T1541C	Pathogenic	0.987
LRP5	O75197-1.2	T1541D	Pathogenic	0.984
LRP5	O75197-1.2	T1541E	Pathogenic	0.985
LRP5	O75197-1.2	T1541F	Pathogenic	0.991
LRP5	O75197-1.2	T1541G	Pathogenic	0.997
LRP5	O75197-1.2	T1541H	Pathogenic	0.997
LRP5	O75197-1.2	T1541I	Pathogenic	0.973
LRP5	O75197-1.2	T1541K	Pathogenic	0.979
LRP5	O75197-1.2	T1541L	Pathogenic	0.975
LRP5	O75197-1.2	T1541M	Pathogenic	0.984
LRP5	O75197-1.2	T1541N	Pathogenic	0.958
LRP5	O75197-1.2	T1541P	Pathogenic	0.99
LRP5	O75197-1.2	T1541Q	Pathogenic	0.99
LRP5	O75197-1.2	T1541R	Pathogenic	0.978
LRP5	O75197-1.2	T1541S	Pathogenic	0.924
LRP5	O75197-1.2	T1541V	Pathogenic	0.953
LRP5	O75197-1.2	T1541W	Pathogenic	0.986
LRP5	O75197-1.2	T1541Y	Pathogenic	0.996
LRP5	O75197-1.2	P1542A	Pathogenic	0.97
LRP5	O75197-1.2	P1542C	Pathogenic	0.997
LRP5	O75197-1.2	P1542D	Pathogenic	0.928
LRP5	O75197-1.2	P1542E	Pathogenic	0.934
LRP5	O75197-1.2	P1542F	Pathogenic	0.998
LRP5	O75197-1.2	P1542G	Pathogenic	0.986
LRP5	O75197-1.2	P1542H	Pathogenic	0.988
LRP5	O75197-1.2	P1542I	Pathogenic	0.994
LRP5	O75197-1.2	P1542K	Pathogenic	0.908
LRP5	O75197-1.2	P1542L	Pathogenic	0.994
LRP5	O75197-1.2	P1542M	Pathogenic	0.989
LRP5	O75197-1.2	P1542N	Pathogenic	0.978
LRP5	O75197-1.2	P1542Q	Pathogenic	0.953
LRP5	O75197-1.2	P1542R	Pathogenic	0.967
LRP5	O75197-1.2	P1542S	Pathogenic	0.96
LRP5	O75197-1.2	P1542T	Pathogenic	0.97
LRP5	O75197-1.2	P1542V	Pathogenic	0.989
LRP5	O75197-1.2	P1542W	Pathogenic	0.997
LRP5	O75197-1.2	P1542Y	Pathogenic	0.997
LRP5	O75197-1.2	C1543A	Pathogenic	0.909
LRP5	O75197-1.2	C1543D	Pathogenic	0.991
LRP5	O75197-1.2	C1543E	Pathogenic	0.997
LRP5	O75197-1.2	C1543F	Pathogenic	0.987
LRP5	O75197-1.2	C1543G	Pathogenic	0.995
LRP5	O75197-1.2	C1543H	Pathogenic	0.996
LRP5	O75197-1.2	C1543I	Pathogenic	0.963
LRP5	O75197-1.2	C1543K	Pathogenic	0.988
LRP5	O75197-1.2	C1543L	Pathogenic	0.966
LRP5	O75197-1.2	C1543M	Pathogenic	0.977
LRP5	O75197-1.2	C1543N	Pathogenic	0.992
LRP5	O75197-1.2	C1543P	Pathogenic	0.998
LRP5	O75197-1.2	C1543Q	Pathogenic	0.994
LRP5	O75197-1.2	C1543R	Pathogenic	0.988
LRP5	O75197-1.2	C1543S	Pathogenic	0.958
LRP5	O75197-1.2	C1543T	Pathogenic	0.967
LRP5	O75197-1.2	C1543V	Pathogenic	0.978
LRP5	O75197-1.2	C1543W	Pathogenic	0.98
LRP5	O75197-1.2	C1543Y	Pathogenic	0.994
LRP5	O75197-1.2	S1544A	Pathogenic	0.876
LRP5	O75197-1.2	S1544C	Pathogenic	0.972
LRP5	O75197-1.2	S1544D	Pathogenic	0.937
LRP5	O75197-1.2	S1544E	Pathogenic	0.942
LRP5	O75197-1.2	S1544F	Pathogenic	0.98
LRP5	O75197-1.2	S1544G	Pathogenic	0.965
LRP5	O75197-1.2	S1544H	Pathogenic	0.986
LRP5	O75197-1.2	S1544I	Pathogenic	0.98
LRP5	O75197-1.2	S1544K	Pathogenic	0.919
LRP5	O75197-1.2	S1544L	Pathogenic	0.982
LRP5	O75197-1.2	S1544M	Pathogenic	0.964
LRP5	O75197-1.2	S1544N	Pathogenic	0.849
LRP5	O75197-1.2	S1544P	Pathogenic	0.978
LRP5	O75197-1.2	S1544Q	Pathogenic	0.959
LRP5	O75197-1.2	S1544R	Pathogenic	0.971
LRP5	O75197-1.2	S1544T	Pathogenic	0.878
LRP5	O75197-1.2	S1544V	Pathogenic	0.988
LRP5	O75197-1.2	S1544W	Pathogenic	0.989
LRP5	O75197-1.2	S1544Y	Pathogenic	0.99
LRP5	O75197-1.2	T1545A	Pathogenic	0.978
LRP5	O75197-1.2	T1545C	Pathogenic	0.987
LRP5	O75197-1.2	T1545D	Pathogenic	0.984
LRP5	O75197-1.2	T1545E	Pathogenic	0.985
LRP5	O75197-1.2	T1545F	Pathogenic	0.991
LRP5	O75197-1.2	T1545G	Pathogenic	0.997
LRP5	O75197-1.2	T1545H	Pathogenic	0.997
LRP5	O75197-1.2	T1545I	Pathogenic	0.973
LRP5	O75197-1.2	T1545K	Pathogenic	0.979
LRP5	O75197-1.2	T1545L	Pathogenic	0.975
LRP5	O75197-1.2	T1545M	Pathogenic	0.984
LRP5	O75197-1.2	T1545N	Pathogenic	0.958
LRP5	O75197-1.2	T1545P	Pathogenic	0.99
LRP5	O75197-1.2	T1545Q	Pathogenic	0.99
LRP5	O75197-1.2	T1545R	Pathogenic	0.978
LRP5	O75197-1.2	T1545S	Pathogenic	0.924
LRP5	O75197-1.2	T1545V	Pathogenic	0.953
LRP5	O75197-1.2	T1545W	Pathogenic	0.986
LRP5	O75197-1.2	T1545Y	Pathogenic	0.996
LRP5	O75197-1.2	D1546A	Neutral	0.053
LRP5	O75197-1.2	D1546C	Neutral	0.087
LRP5	O75197-1.2	D1546E	Neutral	0.002
LRP5	O75197-1.2	D1546F	Neutral	0.042
LRP5	O75197-1.2	D1546G	Neutral	0.023
LRP5	O75197-1.2	D1546H	Neutral	0.021
LRP5	O75197-1.2	D1546I	Neutral	0.042
LRP5	O75197-1.2	D1546K	Neutral	0.037
LRP5	O75197-1.2	D1546L	Neutral	0.127
LRP5	O75197-1.2	D1546M	Neutral	0.068
LRP5	O75197-1.2	D1546N	Neutral	0.005
LRP5	O75197-1.2	D1546P	Neutral	0.013
LRP5	O75197-1.2	D1546Q	Neutral	0.01
LRP5	O75197-1.2	D1546R	Neutral	0.1
LRP5	O75197-1.2	D1546S	Neutral	0.008
LRP5	O75197-1.2	D1546T	Neutral	0.019
LRP5	O75197-1.2	D1546V	Neutral	0.071
LRP5	O75197-1.2	D1546W	Neutral	0.077
LRP5	O75197-1.2	D1546Y	Neutral	0.083
LRP5	O75197-1.2	V1547A	Neutral	0.004
LRP5	O75197-1.2	V1547C	Neutral	0.024
LRP5	O75197-1.2	V1547D	Neutral	0.045
LRP5	O75197-1.2	V1547E	Neutral	0.017
LRP5	O75197-1.2	V1547F	Neutral	0.017
LRP5	O75197-1.2	V1547G	Neutral	0.081
LRP5	O75197-1.2	V1547H	Neutral	0.096
LRP5	O75197-1.2	V1547I	Neutral	0.0
LRP5	O75197-1.2	V1547K	Neutral	0.012
LRP5	O75197-1.2	V1547L	Neutral	0.002
LRP5	O75197-1.2	V1547M	Neutral	0.003
LRP5	O75197-1.2	V1547N	Neutral	0.053
LRP5	O75197-1.2	V1547P	Neutral	0.055
LRP5	O75197-1.2	V1547Q	Neutral	0.025
LRP5	O75197-1.2	V1547R	Neutral	0.035
LRP5	O75197-1.2	V1547S	Neutral	0.028
LRP5	O75197-1.2	V1547T	Neutral	0.004
LRP5	O75197-1.2	V1547W	Neutral	0.094
LRP5	O75197-1.2	V1547Y	Neutral	0.023
LRP5	O75197-1.2	C1548A	Neutral	0.02
LRP5	O75197-1.2	C1548D	Neutral	0.186
LRP5	O75197-1.2	C1548E	Neutral	0.432
LRP5	O75197-1.2	C1548F	Neutral	0.141
LRP5	O75197-1.2	C1548G	Neutral	0.302
LRP5	O75197-1.2	C1548H	Neutral	0.329
LRP5	O75197-1.2	C1548I	Neutral	0.051
LRP5	O75197-1.2	C1548K	Neutral	0.149
LRP5	O75197-1.2	C1548L	Neutral	0.056
LRP5	O75197-1.2	C1548M	Neutral	0.083
LRP5	O75197-1.2	C1548N	Neutral	0.209
LRP5	O75197-1.2	C1548P	Neutral	0.465
LRP5	O75197-1.2	C1548Q	Neutral	0.265
LRP5	O75197-1.2	C1548R	Neutral	0.145
LRP5	O75197-1.2	C1548S	Neutral	0.045
LRP5	O75197-1.2	C1548T	Neutral	0.058
LRP5	O75197-1.2	C1548V	Neutral	0.086
LRP5	O75197-1.2	C1548W	Neutral	0.094
LRP5	O75197-1.2	C1548Y	Neutral	0.246
LRP5	O75197-1.2	D1549A	Neutral	0.009
LRP5	O75197-1.2	D1549C	Neutral	0.015
LRP5	O75197-1.2	D1549E	Neutral	0.0
LRP5	O75197-1.2	D1549F	Neutral	0.007
LRP5	O75197-1.2	D1549G	Neutral	0.004
LRP5	O75197-1.2	D1549H	Neutral	0.003
LRP5	O75197-1.2	D1549I	Neutral	0.007
LRP5	O75197-1.2	D1549K	Neutral	0.006
LRP5	O75197-1.2	D1549L	Neutral	0.023
LRP5	O75197-1.2	D1549M	Neutral	0.012
LRP5	O75197-1.2	D1549N	Neutral	0.001
LRP5	O75197-1.2	D1549P	Neutral	0.002
LRP5	O75197-1.2	D1549Q	Neutral	0.002
LRP5	O75197-1.2	D1549R	Neutral	0.018
LRP5	O75197-1.2	D1549S	Neutral	0.001
LRP5	O75197-1.2	D1549T	Neutral	0.003
LRP5	O75197-1.2	D1549V	Neutral	0.012
LRP5	O75197-1.2	D1549W	Neutral	0.014
LRP5	O75197-1.2	D1549Y	Neutral	0.015
LRP5	O75197-1.2	S1550A	Neutral	0.004
LRP5	O75197-1.2	S1550C	Neutral	0.02
LRP5	O75197-1.2	S1550D	Neutral	0.009
LRP5	O75197-1.2	S1550E	Neutral	0.009
LRP5	O75197-1.2	S1550F	Neutral	0.027
LRP5	O75197-1.2	S1550G	Neutral	0.016
LRP5	O75197-1.2	S1550H	Neutral	0.04
LRP5	O75197-1.2	S1550I	Neutral	0.027
LRP5	O75197-1.2	S1550K	Neutral	0.007
LRP5	O75197-1.2	S1550L	Neutral	0.03
LRP5	O75197-1.2	S1550M	Neutral	0.015
LRP5	O75197-1.2	S1550N	Neutral	0.003
LRP5	O75197-1.2	S1550P	Neutral	0.025
LRP5	O75197-1.2	S1550Q	Neutral	0.013
LRP5	O75197-1.2	S1550R	Neutral	0.019
LRP5	O75197-1.2	S1550T	Neutral	0.004
LRP5	O75197-1.2	S1550V	Neutral	0.047
LRP5	O75197-1.2	S1550W	Neutral	0.051
LRP5	O75197-1.2	S1550Y	Neutral	0.055
LRP5	O75197-1.2	D1551A	Neutral	0.012
LRP5	O75197-1.2	D1551C	Neutral	0.021
LRP5	O75197-1.2	D1551E	Neutral	0.0
LRP5	O75197-1.2	D1551F	Neutral	0.01
LRP5	O75197-1.2	D1551G	Neutral	0.005
LRP5	O75197-1.2	D1551H	Neutral	0.005
LRP5	O75197-1.2	D1551I	Neutral	0.01
LRP5	O75197-1.2	D1551K	Neutral	0.008
LRP5	O75197-1.2	D1551L	Neutral	0.031
LRP5	O75197-1.2	D1551M	Neutral	0.016
LRP5	O75197-1.2	D1551N	Neutral	0.001
LRP5	O75197-1.2	D1551P	Neutral	0.003
LRP5	O75197-1.2	D1551Q	Neutral	0.002
LRP5	O75197-1.2	D1551R	Neutral	0.024
LRP5	O75197-1.2	D1551S	Neutral	0.002
LRP5	O75197-1.2	D1551T	Neutral	0.004
LRP5	O75197-1.2	D1551V	Neutral	0.017
LRP5	O75197-1.2	D1551W	Neutral	0.018
LRP5	O75197-1.2	D1551Y	Neutral	0.02
LRP5	O75197-1.2	Y1552A	Neutral	0.024
LRP5	O75197-1.2	Y1552C	Neutral	0.043
LRP5	O75197-1.2	Y1552D	Neutral	0.029
LRP5	O75197-1.2	Y1552E	Neutral	0.011
LRP5	O75197-1.2	Y1552F	Neutral	0.0
LRP5	O75197-1.2	Y1552G	Neutral	0.052
LRP5	O75197-1.2	Y1552H	Neutral	0.0
LRP5	O75197-1.2	Y1552I	Neutral	0.007
LRP5	O75197-1.2	Y1552K	Neutral	0.009
LRP5	O75197-1.2	Y1552L	Neutral	0.008
LRP5	O75197-1.2	Y1552M	Neutral	0.012
LRP5	O75197-1.2	Y1552N	Neutral	0.011
LRP5	O75197-1.2	Y1552P	Neutral	0.101
LRP5	O75197-1.2	Y1552Q	Neutral	0.005
LRP5	O75197-1.2	Y1552R	Neutral	0.008
LRP5	O75197-1.2	Y1552S	Neutral	0.018
LRP5	O75197-1.2	Y1552T	Neutral	0.024
LRP5	O75197-1.2	Y1552V	Neutral	0.012
LRP5	O75197-1.2	Y1552W	Neutral	0.0
LRP5	O75197-1.2	S1553A	Neutral	0.0
LRP5	O75197-1.2	S1553C	Neutral	0.0
LRP5	O75197-1.2	S1553D	Neutral	0.0
LRP5	O75197-1.2	S1553E	Neutral	0.0
LRP5	O75197-1.2	S1553F	Neutral	0.0
LRP5	O75197-1.2	S1553G	Neutral	0.0
LRP5	O75197-1.2	S1553H	Neutral	0.0
LRP5	O75197-1.2	S1553I	Neutral	0.0
LRP5	O75197-1.2	S1553K	Neutral	0.0
LRP5	O75197-1.2	S1553L	Neutral	0.0
LRP5	O75197-1.2	S1553M	Neutral	0.0
LRP5	O75197-1.2	S1553N	Neutral	0.0
LRP5	O75197-1.2	S1553P	Neutral	0.0
LRP5	O75197-1.2	S1553Q	Neutral	0.0
LRP5	O75197-1.2	S1553R	Neutral	0.0
LRP5	O75197-1.2	S1553T	Neutral	0.0
LRP5	O75197-1.2	S1553V	Neutral	0.0
LRP5	O75197-1.2	S1553W	Neutral	0.0
LRP5	O75197-1.2	S1553Y	Neutral	0.0
LRP5	O75197-1.2	A1554C	Neutral	0.0
LRP5	O75197-1.2	A1554D	Neutral	0.0
LRP5	O75197-1.2	A1554E	Neutral	0.0
LRP5	O75197-1.2	A1554F	Neutral	0.0
LRP5	O75197-1.2	A1554G	Neutral	0.0
LRP5	O75197-1.2	A1554H	Neutral	0.0
LRP5	O75197-1.2	A1554I	Neutral	0.0
LRP5	O75197-1.2	A1554K	Neutral	0.0
LRP5	O75197-1.2	A1554L	Neutral	0.0
LRP5	O75197-1.2	A1554M	Neutral	0.0
LRP5	O75197-1.2	A1554N	Neutral	0.0
LRP5	O75197-1.2	A1554P	Neutral	0.0
LRP5	O75197-1.2	A1554Q	Neutral	0.0
LRP5	O75197-1.2	A1554R	Neutral	0.0
LRP5	O75197-1.2	A1554S	Neutral	0.0
LRP5	O75197-1.2	A1554T	Neutral	0.0
LRP5	O75197-1.2	A1554V	Neutral	0.0
LRP5	O75197-1.2	A1554W	Neutral	0.0
LRP5	O75197-1.2	A1554Y	Neutral	0.0
LRP5	O75197-1.2	S1555A	Neutral	0.0
LRP5	O75197-1.2	S1555C	Neutral	0.002
LRP5	O75197-1.2	S1555D	Neutral	0.001
LRP5	O75197-1.2	S1555E	Neutral	0.001
LRP5	O75197-1.2	S1555F	Neutral	0.003
LRP5	O75197-1.2	S1555G	Neutral	0.002
LRP5	O75197-1.2	S1555H	Neutral	0.004
LRP5	O75197-1.2	S1555I	Neutral	0.003
LRP5	O75197-1.2	S1555K	Neutral	0.001
LRP5	O75197-1.2	S1555L	Neutral	0.003
LRP5	O75197-1.2	S1555M	Neutral	0.001
LRP5	O75197-1.2	S1555N	Neutral	0.0
LRP5	O75197-1.2	S1555P	Neutral	0.003
LRP5	O75197-1.2	S1555Q	Neutral	0.001
LRP5	O75197-1.2	S1555R	Neutral	0.002
LRP5	O75197-1.2	S1555T	Neutral	0.0
LRP5	O75197-1.2	S1555V	Neutral	0.005
LRP5	O75197-1.2	S1555W	Neutral	0.005
LRP5	O75197-1.2	S1555Y	Neutral	0.006
LRP5	O75197-1.2	R1556A	Neutral	0.002
LRP5	O75197-1.2	R1556C	Neutral	0.008
LRP5	O75197-1.2	R1556D	Neutral	0.013
LRP5	O75197-1.2	R1556E	Neutral	0.001
LRP5	O75197-1.2	R1556F	Neutral	0.004
LRP5	O75197-1.2	R1556G	Neutral	0.006
LRP5	O75197-1.2	R1556H	Neutral	0.001
LRP5	O75197-1.2	R1556I	Neutral	0.004
LRP5	O75197-1.2	R1556K	Neutral	0.0
LRP5	O75197-1.2	R1556L	Neutral	0.001
LRP5	O75197-1.2	R1556M	Neutral	0.001
LRP5	O75197-1.2	R1556N	Neutral	0.001
LRP5	O75197-1.2	R1556P	Neutral	0.003
LRP5	O75197-1.2	R1556Q	Neutral	0.0
LRP5	O75197-1.2	R1556S	Neutral	0.002
LRP5	O75197-1.2	R1556T	Neutral	0.002
LRP5	O75197-1.2	R1556V	Neutral	0.007
LRP5	O75197-1.2	R1556W	Neutral	0.003
LRP5	O75197-1.2	R1556Y	Neutral	0.003
LRP5	O75197-1.2	W1557A	Neutral	0.004
LRP5	O75197-1.2	W1557C	Neutral	0.002
LRP5	O75197-1.2	W1557D	Neutral	0.005
LRP5	O75197-1.2	W1557E	Neutral	0.002
LRP5	O75197-1.2	W1557F	Neutral	0.0
LRP5	O75197-1.2	W1557G	Neutral	0.001
LRP5	O75197-1.2	W1557H	Neutral	0.001
LRP5	O75197-1.2	W1557I	Neutral	0.016
LRP5	O75197-1.2	W1557K	Neutral	0.001
LRP5	O75197-1.2	W1557L	Neutral	0.005
LRP5	O75197-1.2	W1557M	Neutral	0.001
LRP5	O75197-1.2	W1557N	Neutral	0.005
LRP5	O75197-1.2	W1557P	Neutral	0.017
LRP5	O75197-1.2	W1557Q	Neutral	0.001
LRP5	O75197-1.2	W1557R	Neutral	0.001
LRP5	O75197-1.2	W1557S	Neutral	0.003
LRP5	O75197-1.2	W1557T	Neutral	0.001
LRP5	O75197-1.2	W1557V	Neutral	0.009
LRP5	O75197-1.2	W1557Y	Neutral	0.0
LRP5	O75197-1.2	K1558A	Neutral	0.0
LRP5	O75197-1.2	K1558C	Neutral	0.002
LRP5	O75197-1.2	K1558D	Neutral	0.001
LRP5	O75197-1.2	K1558E	Neutral	0.0
LRP5	O75197-1.2	K1558F	Neutral	0.001
LRP5	O75197-1.2	K1558G	Neutral	0.001
LRP5	O75197-1.2	K1558H	Neutral	0.0
LRP5	O75197-1.2	K1558I	Neutral	0.001
LRP5	O75197-1.2	K1558L	Neutral	0.0
LRP5	O75197-1.2	K1558M	Neutral	0.0
LRP5	O75197-1.2	K1558N	Neutral	0.0
LRP5	O75197-1.2	K1558P	Neutral	0.0
LRP5	O75197-1.2	K1558Q	Neutral	0.0
LRP5	O75197-1.2	K1558R	Neutral	0.0
LRP5	O75197-1.2	K1558S	Neutral	0.0
LRP5	O75197-1.2	K1558T	Neutral	0.0
LRP5	O75197-1.2	K1558V	Neutral	0.001
LRP5	O75197-1.2	K1558W	Neutral	0.001
LRP5	O75197-1.2	K1558Y	Neutral	0.001
LRP5	O75197-1.2	A1559C	Neutral	0.0
LRP5	O75197-1.2	A1559D	Neutral	0.001
LRP5	O75197-1.2	A1559E	Neutral	0.0
LRP5	O75197-1.2	A1559F	Neutral	0.001
LRP5	O75197-1.2	A1559G	Neutral	0.0
LRP5	O75197-1.2	A1559H	Neutral	0.003
LRP5	O75197-1.2	A1559I	Neutral	0.0
LRP5	O75197-1.2	A1559K	Neutral	0.0
LRP5	O75197-1.2	A1559L	Neutral	0.0
LRP5	O75197-1.2	A1559M	Neutral	0.0
LRP5	O75197-1.2	A1559N	Neutral	0.001
LRP5	O75197-1.2	A1559P	Neutral	0.001
LRP5	O75197-1.2	A1559Q	Neutral	0.001
LRP5	O75197-1.2	A1559R	Neutral	0.0
LRP5	O75197-1.2	A1559S	Neutral	0.0
LRP5	O75197-1.2	A1559T	Neutral	0.0
LRP5	O75197-1.2	A1559V	Neutral	0.0
LRP5	O75197-1.2	A1559W	Neutral	0.002
LRP5	O75197-1.2	A1559Y	Neutral	0.002
LRP5	O75197-1.2	S1560A	Neutral	0.0
LRP5	O75197-1.2	S1560C	Neutral	0.0
LRP5	O75197-1.2	S1560D	Neutral	0.0
LRP5	O75197-1.2	S1560E	Neutral	0.0
LRP5	O75197-1.2	S1560F	Neutral	0.0
LRP5	O75197-1.2	S1560G	Neutral	0.0
LRP5	O75197-1.2	S1560H	Neutral	0.0
LRP5	O75197-1.2	S1560I	Neutral	0.0
LRP5	O75197-1.2	S1560K	Neutral	0.0
LRP5	O75197-1.2	S1560L	Neutral	0.0
LRP5	O75197-1.2	S1560M	Neutral	0.0
LRP5	O75197-1.2	S1560N	Neutral	0.0
LRP5	O75197-1.2	S1560P	Neutral	0.0
LRP5	O75197-1.2	S1560Q	Neutral	0.0
LRP5	O75197-1.2	S1560R	Neutral	0.0
LRP5	O75197-1.2	S1560T	Neutral	0.0
LRP5	O75197-1.2	S1560V	Neutral	0.0
LRP5	O75197-1.2	S1560W	Neutral	0.0
LRP5	O75197-1.2	S1560Y	Neutral	0.0
LRP5	O75197-1.2	K1561A	Neutral	0.0
LRP5	O75197-1.2	K1561C	Neutral	0.002
LRP5	O75197-1.2	K1561D	Neutral	0.001
LRP5	O75197-1.2	K1561E	Neutral	0.0
LRP5	O75197-1.2	K1561F	Neutral	0.001
LRP5	O75197-1.2	K1561G	Neutral	0.002
LRP5	O75197-1.2	K1561H	Neutral	0.001
LRP5	O75197-1.2	K1561I	Neutral	0.001
LRP5	O75197-1.2	K1561L	Neutral	0.0
LRP5	O75197-1.2	K1561M	Neutral	0.0
LRP5	O75197-1.2	K1561N	Neutral	0.0
LRP5	O75197-1.2	K1561P	Neutral	0.0
LRP5	O75197-1.2	K1561Q	Neutral	0.0
LRP5	O75197-1.2	K1561R	Neutral	0.0
LRP5	O75197-1.2	K1561S	Neutral	0.0
LRP5	O75197-1.2	K1561T	Neutral	0.001
LRP5	O75197-1.2	K1561V	Neutral	0.001
LRP5	O75197-1.2	K1561W	Neutral	0.001
LRP5	O75197-1.2	K1561Y	Neutral	0.001
LRP5	O75197-1.2	Y1562A	Neutral	0.068
LRP5	O75197-1.2	Y1562C	Neutral	0.117
LRP5	O75197-1.2	Y1562D	Neutral	0.081
LRP5	O75197-1.2	Y1562E	Neutral	0.032
LRP5	O75197-1.2	Y1562F	Neutral	0.0
LRP5	O75197-1.2	Y1562G	Neutral	0.14
LRP5	O75197-1.2	Y1562H	Neutral	0.001
LRP5	O75197-1.2	Y1562I	Neutral	0.022
LRP5	O75197-1.2	Y1562K	Neutral	0.025
LRP5	O75197-1.2	Y1562L	Neutral	0.024
LRP5	O75197-1.2	Y1562M	Neutral	0.036
LRP5	O75197-1.2	Y1562N	Neutral	0.033
LRP5	O75197-1.2	Y1562P	Neutral	0.249
LRP5	O75197-1.2	Y1562Q	Neutral	0.016
LRP5	O75197-1.2	Y1562R	Neutral	0.025
LRP5	O75197-1.2	Y1562S	Neutral	0.051
LRP5	O75197-1.2	Y1562T	Neutral	0.068
LRP5	O75197-1.2	Y1562V	Neutral	0.035
LRP5	O75197-1.2	Y1562W	Neutral	0.001
LRP5	O75197-1.2	Y1563A	Neutral	0.001
LRP5	O75197-1.2	Y1563C	Neutral	0.002
LRP5	O75197-1.2	Y1563D	Neutral	0.002
LRP5	O75197-1.2	Y1563E	Neutral	0.001
LRP5	O75197-1.2	Y1563F	Neutral	0.0
LRP5	O75197-1.2	Y1563G	Neutral	0.003
LRP5	O75197-1.2	Y1563H	Neutral	0.0
LRP5	O75197-1.2	Y1563I	Neutral	0.0
LRP5	O75197-1.2	Y1563K	Neutral	0.0
LRP5	O75197-1.2	Y1563L	Neutral	0.0
LRP5	O75197-1.2	Y1563M	Neutral	0.001
LRP5	O75197-1.2	Y1563N	Neutral	0.001
LRP5	O75197-1.2	Y1563P	Neutral	0.006
LRP5	O75197-1.2	Y1563Q	Neutral	0.0
LRP5	O75197-1.2	Y1563R	Neutral	0.0
LRP5	O75197-1.2	Y1563S	Neutral	0.001
LRP5	O75197-1.2	Y1563T	Neutral	0.001
LRP5	O75197-1.2	Y1563V	Neutral	0.001
LRP5	O75197-1.2	Y1563W	Neutral	0.0
LRP5	O75197-1.2	L1564A	Neutral	0.0
LRP5	O75197-1.2	L1564C	Neutral	0.0
LRP5	O75197-1.2	L1564D	Neutral	0.0
LRP5	O75197-1.2	L1564E	Neutral	0.0
LRP5	O75197-1.2	L1564F	Neutral	0.0
LRP5	O75197-1.2	L1564G	Neutral	0.0
LRP5	O75197-1.2	L1564H	Neutral	0.0
LRP5	O75197-1.2	L1564I	Neutral	0.0
LRP5	O75197-1.2	L1564K	Neutral	0.0
LRP5	O75197-1.2	L1564M	Neutral	0.0
LRP5	O75197-1.2	L1564N	Neutral	0.0
LRP5	O75197-1.2	L1564P	Neutral	0.0
LRP5	O75197-1.2	L1564Q	Neutral	0.0
LRP5	O75197-1.2	L1564R	Neutral	0.0
LRP5	O75197-1.2	L1564S	Neutral	0.0
LRP5	O75197-1.2	L1564T	Neutral	0.0
LRP5	O75197-1.2	L1564V	Neutral	0.0
LRP5	O75197-1.2	L1564W	Neutral	0.0
LRP5	O75197-1.2	L1564Y	Neutral	0.0
LRP5	O75197-1.2	D1565A	Neutral	0.014
LRP5	O75197-1.2	D1565C	Neutral	0.025
LRP5	O75197-1.2	D1565E	Neutral	0.0
LRP5	O75197-1.2	D1565F	Neutral	0.011
LRP5	O75197-1.2	D1565G	Neutral	0.006
LRP5	O75197-1.2	D1565H	Neutral	0.006
LRP5	O75197-1.2	D1565I	Neutral	0.011
LRP5	O75197-1.2	D1565K	Neutral	0.01
LRP5	O75197-1.2	D1565L	Neutral	0.037
LRP5	O75197-1.2	D1565M	Neutral	0.019
LRP5	O75197-1.2	D1565N	Neutral	0.001
LRP5	O75197-1.2	D1565P	Neutral	0.003
LRP5	O75197-1.2	D1565Q	Neutral	0.003
LRP5	O75197-1.2	D1565R	Neutral	0.029
LRP5	O75197-1.2	D1565S	Neutral	0.002
LRP5	O75197-1.2	D1565T	Neutral	0.005
LRP5	O75197-1.2	D1565V	Neutral	0.02
LRP5	O75197-1.2	D1565W	Neutral	0.022
LRP5	O75197-1.2	D1565Y	Neutral	0.023
LRP5	O75197-1.2	L1566A	Neutral	0.002
LRP5	O75197-1.2	L1566C	Neutral	0.004
LRP5	O75197-1.2	L1566D	Neutral	0.025
LRP5	O75197-1.2	L1566E	Neutral	0.01
LRP5	O75197-1.2	L1566F	Neutral	0.003
LRP5	O75197-1.2	L1566G	Neutral	0.045
LRP5	O75197-1.2	L1566H	Neutral	0.019
LRP5	O75197-1.2	L1566I	Neutral	0.0
LRP5	O75197-1.2	L1566K	Neutral	0.002
LRP5	O75197-1.2	L1566M	Neutral	0.0
LRP5	O75197-1.2	L1566N	Neutral	0.01
LRP5	O75197-1.2	L1566P	Neutral	0.03
LRP5	O75197-1.2	L1566Q	Neutral	0.005
LRP5	O75197-1.2	L1566R	Neutral	0.002
LRP5	O75197-1.2	L1566S	Neutral	0.005
LRP5	O75197-1.2	L1566T	Neutral	0.002
LRP5	O75197-1.2	L1566V	Neutral	0.001
LRP5	O75197-1.2	L1566W	Neutral	0.015
LRP5	O75197-1.2	L1566Y	Neutral	0.004
LRP5	O75197-1.2	N1567A	Neutral	0.012
LRP5	O75197-1.2	N1567C	Neutral	0.02
LRP5	O75197-1.2	N1567D	Neutral	0.001
LRP5	O75197-1.2	N1567E	Neutral	0.003
LRP5	O75197-1.2	N1567F	Neutral	0.009
LRP5	O75197-1.2	N1567G	Neutral	0.002
LRP5	O75197-1.2	N1567H	Neutral	0.0
LRP5	O75197-1.2	N1567I	Neutral	0.009
LRP5	O75197-1.2	N1567K	Neutral	0.002
LRP5	O75197-1.2	N1567L	Neutral	0.01
LRP5	O75197-1.2	N1567M	Neutral	0.005
LRP5	O75197-1.2	N1567P	Neutral	0.008
LRP5	O75197-1.2	N1567Q	Neutral	0.002
LRP5	O75197-1.2	N1567R	Neutral	0.002
LRP5	O75197-1.2	N1567S	Neutral	0.001
LRP5	O75197-1.2	N1567T	Neutral	0.001
LRP5	O75197-1.2	N1567V	Neutral	0.016
LRP5	O75197-1.2	N1567W	Neutral	0.018
LRP5	O75197-1.2	N1567Y	Neutral	0.006
LRP5	O75197-1.2	S1568A	Neutral	0.0
LRP5	O75197-1.2	S1568C	Neutral	0.001
LRP5	O75197-1.2	S1568D	Neutral	0.0
LRP5	O75197-1.2	S1568E	Neutral	0.0
LRP5	O75197-1.2	S1568F	Neutral	0.001
LRP5	O75197-1.2	S1568G	Neutral	0.001
LRP5	O75197-1.2	S1568H	Neutral	0.002
LRP5	O75197-1.2	S1568I	Neutral	0.001
LRP5	O75197-1.2	S1568K	Neutral	0.0
LRP5	O75197-1.2	S1568L	Neutral	0.001
LRP5	O75197-1.2	S1568M	Neutral	0.001
LRP5	O75197-1.2	S1568N	Neutral	0.0
LRP5	O75197-1.2	S1568P	Neutral	0.001
LRP5	O75197-1.2	S1568Q	Neutral	0.001
LRP5	O75197-1.2	S1568R	Neutral	0.001
LRP5	O75197-1.2	S1568T	Neutral	0.0
LRP5	O75197-1.2	S1568V	Neutral	0.002
LRP5	O75197-1.2	S1568W	Neutral	0.002
LRP5	O75197-1.2	S1568Y	Neutral	0.002
LRP5	O75197-1.2	D1569A	Neutral	0.009
LRP5	O75197-1.2	D1569C	Neutral	0.016
LRP5	O75197-1.2	D1569E	Neutral	0.0
LRP5	O75197-1.2	D1569F	Neutral	0.007
LRP5	O75197-1.2	D1569G	Neutral	0.004
LRP5	O75197-1.2	D1569H	Neutral	0.004
LRP5	O75197-1.2	D1569I	Neutral	0.007
LRP5	O75197-1.2	D1569K	Neutral	0.007
LRP5	O75197-1.2	D1569L	Neutral	0.024
LRP5	O75197-1.2	D1569M	Neutral	0.012
LRP5	O75197-1.2	D1569N	Neutral	0.001
LRP5	O75197-1.2	D1569P	Neutral	0.002
LRP5	O75197-1.2	D1569Q	Neutral	0.002
LRP5	O75197-1.2	D1569R	Neutral	0.019
LRP5	O75197-1.2	D1569S	Neutral	0.001
LRP5	O75197-1.2	D1569T	Neutral	0.003
LRP5	O75197-1.2	D1569V	Neutral	0.013
LRP5	O75197-1.2	D1569W	Neutral	0.014
LRP5	O75197-1.2	D1569Y	Neutral	0.015
LRP5	O75197-1.2	S1570A	Neutral	0.003
LRP5	O75197-1.2	S1570C	Neutral	0.013
LRP5	O75197-1.2	S1570D	Neutral	0.006
LRP5	O75197-1.2	S1570E	Neutral	0.006
LRP5	O75197-1.2	S1570F	Neutral	0.018
LRP5	O75197-1.2	S1570G	Neutral	0.01
LRP5	O75197-1.2	S1570H	Neutral	0.027
LRP5	O75197-1.2	S1570I	Neutral	0.018
LRP5	O75197-1.2	S1570K	Neutral	0.004
LRP5	O75197-1.2	S1570L	Neutral	0.02
LRP5	O75197-1.2	S1570M	Neutral	0.01
LRP5	O75197-1.2	S1570N	Neutral	0.002
LRP5	O75197-1.2	S1570P	Neutral	0.017
LRP5	O75197-1.2	S1570Q	Neutral	0.009
LRP5	O75197-1.2	S1570R	Neutral	0.013
LRP5	O75197-1.2	S1570T	Neutral	0.003
LRP5	O75197-1.2	S1570V	Neutral	0.031
LRP5	O75197-1.2	S1570W	Neutral	0.034
LRP5	O75197-1.2	S1570Y	Neutral	0.037
LRP5	O75197-1.2	D1571A	Neutral	0.001
LRP5	O75197-1.2	D1571C	Neutral	0.002
LRP5	O75197-1.2	D1571E	Neutral	0.0
LRP5	O75197-1.2	D1571F	Neutral	0.001
LRP5	O75197-1.2	D1571G	Neutral	0.0
LRP5	O75197-1.2	D1571H	Neutral	0.0
LRP5	O75197-1.2	D1571I	Neutral	0.001
LRP5	O75197-1.2	D1571K	Neutral	0.001
LRP5	O75197-1.2	D1571L	Neutral	0.003
LRP5	O75197-1.2	D1571M	Neutral	0.001
LRP5	O75197-1.2	D1571N	Neutral	0.0
LRP5	O75197-1.2	D1571P	Neutral	0.0
LRP5	O75197-1.2	D1571Q	Neutral	0.0
LRP5	O75197-1.2	D1571R	Neutral	0.002
LRP5	O75197-1.2	D1571S	Neutral	0.0
LRP5	O75197-1.2	D1571T	Neutral	0.0
LRP5	O75197-1.2	D1571V	Neutral	0.001
LRP5	O75197-1.2	D1571W	Neutral	0.001
LRP5	O75197-1.2	D1571Y	Neutral	0.002
LRP5	O75197-1.2	P1572A	Neutral	0.089
LRP5	O75197-1.2	P1572C	Pathogenic	0.514
LRP5	O75197-1.2	P1572D	Neutral	0.037
LRP5	O75197-1.2	P1572E	Neutral	0.04
LRP5	O75197-1.2	P1572F	Pathogenic	0.594
LRP5	O75197-1.2	P1572G	Neutral	0.179
LRP5	O75197-1.2	P1572H	Neutral	0.2
LRP5	O75197-1.2	P1572I	Neutral	0.326
LRP5	O75197-1.2	P1572K	Neutral	0.029
LRP5	O75197-1.2	P1572L	Neutral	0.346
LRP5	O75197-1.2	P1572M	Neutral	0.209
LRP5	O75197-1.2	P1572N	Neutral	0.119
LRP5	O75197-1.2	P1572Q	Neutral	0.057
LRP5	O75197-1.2	P1572R	Neutral	0.08
LRP5	O75197-1.2	P1572S	Neutral	0.067
LRP5	O75197-1.2	P1572T	Neutral	0.087
LRP5	O75197-1.2	P1572V	Neutral	0.217
LRP5	O75197-1.2	P1572W	Neutral	0.481
LRP5	O75197-1.2	P1572Y	Neutral	0.5
LRP5	O75197-1.2	Y1573A	Neutral	0.002
LRP5	O75197-1.2	Y1573C	Neutral	0.003
LRP5	O75197-1.2	Y1573D	Neutral	0.002
LRP5	O75197-1.2	Y1573E	Neutral	0.001
LRP5	O75197-1.2	Y1573F	Neutral	0.0
LRP5	O75197-1.2	Y1573G	Neutral	0.004
LRP5	O75197-1.2	Y1573H	Neutral	0.0
LRP5	O75197-1.2	Y1573I	Neutral	0.001
LRP5	O75197-1.2	Y1573K	Neutral	0.001
LRP5	O75197-1.2	Y1573L	Neutral	0.001
LRP5	O75197-1.2	Y1573M	Neutral	0.001
LRP5	O75197-1.2	Y1573N	Neutral	0.001
LRP5	O75197-1.2	Y1573P	Neutral	0.008
LRP5	O75197-1.2	Y1573Q	Neutral	0.0
LRP5	O75197-1.2	Y1573R	Neutral	0.001
LRP5	O75197-1.2	Y1573S	Neutral	0.001
LRP5	O75197-1.2	Y1573T	Neutral	0.002
LRP5	O75197-1.2	Y1573V	Neutral	0.001
LRP5	O75197-1.2	Y1573W	Neutral	0.0
LRP5	O75197-1.2	P1574A	Pathogenic	0.955
LRP5	O75197-1.2	P1574C	Pathogenic	0.996
LRP5	O75197-1.2	P1574D	Pathogenic	0.893
LRP5	O75197-1.2	P1574E	Pathogenic	0.901
LRP5	O75197-1.2	P1574F	Pathogenic	0.997
LRP5	O75197-1.2	P1574G	Pathogenic	0.979
LRP5	O75197-1.2	P1574H	Pathogenic	0.982
LRP5	O75197-1.2	P1574I	Pathogenic	0.991
LRP5	O75197-1.2	P1574K	Pathogenic	0.865
LRP5	O75197-1.2	P1574L	Pathogenic	0.991
LRP5	O75197-1.2	P1574M	Pathogenic	0.983
LRP5	O75197-1.2	P1574N	Pathogenic	0.967
LRP5	O75197-1.2	P1574Q	Pathogenic	0.929
LRP5	O75197-1.2	P1574R	Pathogenic	0.949
LRP5	O75197-1.2	P1574S	Pathogenic	0.94
LRP5	O75197-1.2	P1574T	Pathogenic	0.954
LRP5	O75197-1.2	P1574V	Pathogenic	0.984
LRP5	O75197-1.2	P1574W	Pathogenic	0.995
LRP5	O75197-1.2	P1574Y	Pathogenic	0.995
LRP5	O75197-1.2	P1575A	Pathogenic	0.989
LRP5	O75197-1.2	P1575C	Pathogenic	0.999
LRP5	O75197-1.2	P1575D	Pathogenic	0.971
LRP5	O75197-1.2	P1575E	Pathogenic	0.974
LRP5	O75197-1.2	P1575F	Pathogenic	0.999
LRP5	O75197-1.2	P1575G	Pathogenic	0.995
LRP5	O75197-1.2	P1575H	Pathogenic	0.996
LRP5	O75197-1.2	P1575I	Pathogenic	0.998
LRP5	O75197-1.2	P1575K	Pathogenic	0.963
LRP5	O75197-1.2	P1575L	Pathogenic	0.998
LRP5	O75197-1.2	P1575M	Pathogenic	0.996
LRP5	O75197-1.2	P1575N	Pathogenic	0.992
LRP5	O75197-1.2	P1575Q	Pathogenic	0.982
LRP5	O75197-1.2	P1575R	Pathogenic	0.987
LRP5	O75197-1.2	P1575S	Pathogenic	0.985
LRP5	O75197-1.2	P1575T	Pathogenic	0.988
LRP5	O75197-1.2	P1575V	Pathogenic	0.996
LRP5	O75197-1.2	P1575W	Pathogenic	0.999
LRP5	O75197-1.2	P1575Y	Pathogenic	0.999
LRP5	O75197-1.2	P1576A	Pathogenic	0.972
LRP5	O75197-1.2	P1576C	Pathogenic	0.997
LRP5	O75197-1.2	P1576D	Pathogenic	0.931
LRP5	O75197-1.2	P1576E	Pathogenic	0.937
LRP5	O75197-1.2	P1576F	Pathogenic	0.998
LRP5	O75197-1.2	P1576G	Pathogenic	0.987
LRP5	O75197-1.2	P1576H	Pathogenic	0.989
LRP5	O75197-1.2	P1576I	Pathogenic	0.994
LRP5	O75197-1.2	P1576K	Pathogenic	0.912
LRP5	O75197-1.2	P1576L	Pathogenic	0.995
LRP5	O75197-1.2	P1576M	Pathogenic	0.989
LRP5	O75197-1.2	P1576N	Pathogenic	0.979
LRP5	O75197-1.2	P1576Q	Pathogenic	0.955
LRP5	O75197-1.2	P1576R	Pathogenic	0.968
LRP5	O75197-1.2	P1576S	Pathogenic	0.962
LRP5	O75197-1.2	P1576T	Pathogenic	0.971
LRP5	O75197-1.2	P1576V	Pathogenic	0.99
LRP5	O75197-1.2	P1576W	Pathogenic	0.997
LRP5	O75197-1.2	P1576Y	Pathogenic	0.997
LRP5	O75197-1.2	P1577A	Pathogenic	0.989
LRP5	O75197-1.2	P1577C	Pathogenic	0.999
LRP5	O75197-1.2	P1577D	Pathogenic	0.972
LRP5	O75197-1.2	P1577E	Pathogenic	0.975
LRP5	O75197-1.2	P1577F	Pathogenic	0.999
LRP5	O75197-1.2	P1577G	Pathogenic	0.995
LRP5	O75197-1.2	P1577H	Pathogenic	0.996
LRP5	O75197-1.2	P1577I	Pathogenic	0.998
LRP5	O75197-1.2	P1577K	Pathogenic	0.964
LRP5	O75197-1.2	P1577L	Pathogenic	0.998
LRP5	O75197-1.2	P1577M	Pathogenic	0.996
LRP5	O75197-1.2	P1577N	Pathogenic	0.992
LRP5	O75197-1.2	P1577Q	Pathogenic	0.982
LRP5	O75197-1.2	P1577R	Pathogenic	0.988
LRP5	O75197-1.2	P1577S	Pathogenic	0.985
LRP5	O75197-1.2	P1577T	Pathogenic	0.989
LRP5	O75197-1.2	P1577V	Pathogenic	0.996
LRP5	O75197-1.2	P1577W	Pathogenic	0.999
LRP5	O75197-1.2	P1577Y	Pathogenic	0.999
LRP5	O75197-1.2	T1578A	Pathogenic	0.935
LRP5	O75197-1.2	T1578C	Pathogenic	0.961
LRP5	O75197-1.2	T1578D	Pathogenic	0.95
LRP5	O75197-1.2	T1578E	Pathogenic	0.954
LRP5	O75197-1.2	T1578F	Pathogenic	0.972
LRP5	O75197-1.2	T1578G	Pathogenic	0.991
LRP5	O75197-1.2	T1578H	Pathogenic	0.992
LRP5	O75197-1.2	T1578I	Pathogenic	0.919
LRP5	O75197-1.2	T1578K	Pathogenic	0.936
LRP5	O75197-1.2	T1578L	Pathogenic	0.926
LRP5	O75197-1.2	T1578M	Pathogenic	0.95
LRP5	O75197-1.2	T1578N	Pathogenic	0.879
LRP5	O75197-1.2	T1578P	Pathogenic	0.969
LRP5	O75197-1.2	T1578Q	Pathogenic	0.968
LRP5	O75197-1.2	T1578R	Pathogenic	0.934
LRP5	O75197-1.2	T1578S	Pathogenic	0.793
LRP5	O75197-1.2	T1578V	Pathogenic	0.867
LRP5	O75197-1.2	T1578W	Pathogenic	0.956
LRP5	O75197-1.2	T1578Y	Pathogenic	0.986
LRP5	O75197-1.2	P1579A	Pathogenic	0.989
LRP5	O75197-1.2	P1579C	Pathogenic	0.999
LRP5	O75197-1.2	P1579D	Pathogenic	0.974
LRP5	O75197-1.2	P1579E	Pathogenic	0.976
LRP5	O75197-1.2	P1579F	Pathogenic	0.999
LRP5	O75197-1.2	P1579G	Pathogenic	0.995
LRP5	O75197-1.2	P1579H	Pathogenic	0.996
LRP5	O75197-1.2	P1579I	Pathogenic	0.998
LRP5	O75197-1.2	P1579K	Pathogenic	0.966
LRP5	O75197-1.2	P1579L	Pathogenic	0.998
LRP5	O75197-1.2	P1579M	Pathogenic	0.996
LRP5	O75197-1.2	P1579N	Pathogenic	0.992
LRP5	O75197-1.2	P1579Q	Pathogenic	0.983
LRP5	O75197-1.2	P1579R	Pathogenic	0.988
LRP5	O75197-1.2	P1579S	Pathogenic	0.986
LRP5	O75197-1.2	P1579T	Pathogenic	0.989
LRP5	O75197-1.2	P1579V	Pathogenic	0.996
LRP5	O75197-1.2	P1579W	Pathogenic	0.999
LRP5	O75197-1.2	P1579Y	Pathogenic	0.999
LRP5	O75197-1.2	H1580A	Pathogenic	0.751
LRP5	O75197-1.2	H1580C	Pathogenic	0.838
LRP5	O75197-1.2	H1580D	Neutral	0.35
LRP5	O75197-1.2	H1580E	Neutral	0.17
LRP5	O75197-1.2	H1580F	Neutral	0.218
LRP5	O75197-1.2	H1580G	Pathogenic	0.753
LRP5	O75197-1.2	H1580I	Pathogenic	0.721
LRP5	O75197-1.2	H1580K	Neutral	0.31
LRP5	O75197-1.2	H1580L	Pathogenic	0.74
LRP5	O75197-1.2	H1580M	Pathogenic	0.587
LRP5	O75197-1.2	H1580N	Neutral	0.064
LRP5	O75197-1.2	H1580P	Pathogenic	0.684
LRP5	O75197-1.2	H1580Q	Neutral	0.231
LRP5	O75197-1.2	H1580R	Neutral	0.125
LRP5	O75197-1.2	H1580S	Pathogenic	0.502
LRP5	O75197-1.2	H1580T	Pathogenic	0.767
LRP5	O75197-1.2	H1580V	Pathogenic	0.812
LRP5	O75197-1.2	H1580W	Neutral	0.349
LRP5	O75197-1.2	H1580Y	Neutral	0.02
LRP5	O75197-1.2	S1581A	Pathogenic	0.809
LRP5	O75197-1.2	S1581C	Pathogenic	0.955
LRP5	O75197-1.2	S1581D	Pathogenic	0.899
LRP5	O75197-1.2	S1581E	Pathogenic	0.907
LRP5	O75197-1.2	S1581F	Pathogenic	0.967
LRP5	O75197-1.2	S1581G	Pathogenic	0.943
LRP5	O75197-1.2	S1581H	Pathogenic	0.977
LRP5	O75197-1.2	S1581I	Pathogenic	0.967
LRP5	O75197-1.2	S1581K	Pathogenic	0.872
LRP5	O75197-1.2	S1581L	Pathogenic	0.97
LRP5	O75197-1.2	S1581M	Pathogenic	0.941
LRP5	O75197-1.2	S1581N	Pathogenic	0.771
LRP5	O75197-1.2	S1581P	Pathogenic	0.964
LRP5	O75197-1.2	S1581Q	Pathogenic	0.933
LRP5	O75197-1.2	S1581R	Pathogenic	0.952
LRP5	O75197-1.2	S1581T	Pathogenic	0.812
LRP5	O75197-1.2	S1581V	Pathogenic	0.981
LRP5	O75197-1.2	S1581W	Pathogenic	0.982
LRP5	O75197-1.2	S1581Y	Pathogenic	0.984
LRP5	O75197-1.2	Q1582A	Neutral	0.003
LRP5	O75197-1.2	Q1582C	Neutral	0.016
LRP5	O75197-1.2	Q1582D	Neutral	0.001
LRP5	O75197-1.2	Q1582E	Neutral	0.0
LRP5	O75197-1.2	Q1582F	Neutral	0.008
LRP5	O75197-1.2	Q1582G	Neutral	0.012
LRP5	O75197-1.2	Q1582H	Neutral	0.001
LRP5	O75197-1.2	Q1582I	Neutral	0.008
LRP5	O75197-1.2	Q1582K	Neutral	0.0
LRP5	O75197-1.2	Q1582L	Neutral	0.003
LRP5	O75197-1.2	Q1582M	Neutral	0.0
LRP5	O75197-1.2	Q1582N	Neutral	0.001
LRP5	O75197-1.2	Q1582P	Neutral	0.002
LRP5	O75197-1.2	Q1582R	Neutral	0.0
LRP5	O75197-1.2	Q1582S	Neutral	0.001
LRP5	O75197-1.2	Q1582T	Neutral	0.003
LRP5	O75197-1.2	Q1582V	Neutral	0.005
LRP5	O75197-1.2	Q1582W	Neutral	0.002
LRP5	O75197-1.2	Q1582Y	Neutral	0.002
LRP5	O75197-1.2	Y1583A	Neutral	0.129
LRP5	O75197-1.2	Y1583C	Neutral	0.211
LRP5	O75197-1.2	Y1583D	Neutral	0.151
LRP5	O75197-1.2	Y1583E	Neutral	0.064
LRP5	O75197-1.2	Y1583F	Neutral	0.001
LRP5	O75197-1.2	Y1583G	Neutral	0.249
LRP5	O75197-1.2	Y1583H	Neutral	0.002
LRP5	O75197-1.2	Y1583I	Neutral	0.043
LRP5	O75197-1.2	Y1583K	Neutral	0.049
LRP5	O75197-1.2	Y1583L	Neutral	0.047
LRP5	O75197-1.2	Y1583M	Neutral	0.07
LRP5	O75197-1.2	Y1583N	Neutral	0.064
LRP5	O75197-1.2	Y1583P	Neutral	0.403
LRP5	O75197-1.2	Y1583Q	Neutral	0.032
LRP5	O75197-1.2	Y1583R	Neutral	0.048
LRP5	O75197-1.2	Y1583S	Neutral	0.099
LRP5	O75197-1.2	Y1583T	Neutral	0.128
LRP5	O75197-1.2	Y1583V	Neutral	0.069
LRP5	O75197-1.2	Y1583W	Neutral	0.001
LRP5	O75197-1.2	L1584A	Neutral	0.0
LRP5	O75197-1.2	L1584C	Neutral	0.0
LRP5	O75197-1.2	L1584D	Neutral	0.002
LRP5	O75197-1.2	L1584E	Neutral	0.001
LRP5	O75197-1.2	L1584F	Neutral	0.0
LRP5	O75197-1.2	L1584G	Neutral	0.003
LRP5	O75197-1.2	L1584H	Neutral	0.001
LRP5	O75197-1.2	L1584I	Neutral	0.0
LRP5	O75197-1.2	L1584K	Neutral	0.0
LRP5	O75197-1.2	L1584M	Neutral	0.0
LRP5	O75197-1.2	L1584N	Neutral	0.001
LRP5	O75197-1.2	L1584P	Neutral	0.002
LRP5	O75197-1.2	L1584Q	Neutral	0.0
LRP5	O75197-1.2	L1584R	Neutral	0.0
LRP5	O75197-1.2	L1584S	Neutral	0.0
LRP5	O75197-1.2	L1584T	Neutral	0.0
LRP5	O75197-1.2	L1584V	Neutral	0.0
LRP5	O75197-1.2	L1584W	Neutral	0.001
LRP5	O75197-1.2	L1584Y	Neutral	0.0
LRP5	O75197-1.2	S1585A	Neutral	0.002
LRP5	O75197-1.2	S1585C	Neutral	0.011
LRP5	O75197-1.2	S1585D	Neutral	0.005
LRP5	O75197-1.2	S1585E	Neutral	0.005
LRP5	O75197-1.2	S1585F	Neutral	0.015
LRP5	O75197-1.2	S1585G	Neutral	0.008
LRP5	O75197-1.2	S1585H	Neutral	0.022
LRP5	O75197-1.2	S1585I	Neutral	0.015
LRP5	O75197-1.2	S1585K	Neutral	0.004
LRP5	O75197-1.2	S1585L	Neutral	0.016
LRP5	O75197-1.2	S1585M	Neutral	0.008
LRP5	O75197-1.2	S1585N	Neutral	0.002
LRP5	O75197-1.2	S1585P	Neutral	0.014
LRP5	O75197-1.2	S1585Q	Neutral	0.007
LRP5	O75197-1.2	S1585R	Neutral	0.01
LRP5	O75197-1.2	S1585T	Neutral	0.002
LRP5	O75197-1.2	S1585V	Neutral	0.025
LRP5	O75197-1.2	S1585W	Neutral	0.028
LRP5	O75197-1.2	S1585Y	Neutral	0.03
LRP5	O75197-1.2	A1586C	Neutral	0.001
LRP5	O75197-1.2	A1586D	Neutral	0.005
LRP5	O75197-1.2	A1586E	Neutral	0.002
LRP5	O75197-1.2	A1586F	Neutral	0.003
LRP5	O75197-1.2	A1586G	Neutral	0.001
LRP5	O75197-1.2	A1586H	Neutral	0.01
LRP5	O75197-1.2	A1586I	Neutral	0.001
LRP5	O75197-1.2	A1586K	Neutral	0.001
LRP5	O75197-1.2	A1586L	Neutral	0.001
LRP5	O75197-1.2	A1586M	Neutral	0.002
LRP5	O75197-1.2	A1586N	Neutral	0.005
LRP5	O75197-1.2	A1586P	Neutral	0.003
LRP5	O75197-1.2	A1586Q	Neutral	0.002
LRP5	O75197-1.2	A1586R	Neutral	0.001
LRP5	O75197-1.2	A1586S	Neutral	0.0
LRP5	O75197-1.2	A1586T	Neutral	0.001
LRP5	O75197-1.2	A1586V	Neutral	0.001
LRP5	O75197-1.2	A1586W	Neutral	0.006
LRP5	O75197-1.2	A1586Y	Neutral	0.006
LRP5	O75197-1.2	E1587A	Neutral	0.003
LRP5	O75197-1.2	E1587C	Neutral	0.046
LRP5	O75197-1.2	E1587D	Neutral	0.0
LRP5	O75197-1.2	E1587F	Neutral	0.008
LRP5	O75197-1.2	E1587G	Neutral	0.012
LRP5	O75197-1.2	E1587H	Neutral	0.001
LRP5	O75197-1.2	E1587I	Neutral	0.008
LRP5	O75197-1.2	E1587K	Neutral	0.001
LRP5	O75197-1.2	E1587L	Neutral	0.008
LRP5	O75197-1.2	E1587M	Neutral	0.004
LRP5	O75197-1.2	E1587N	Neutral	0.002
LRP5	O75197-1.2	E1587P	Neutral	0.002
LRP5	O75197-1.2	E1587Q	Neutral	0.0
LRP5	O75197-1.2	E1587R	Neutral	0.002
LRP5	O75197-1.2	E1587S	Neutral	0.001
LRP5	O75197-1.2	E1587T	Neutral	0.003
LRP5	O75197-1.2	E1587V	Neutral	0.004
LRP5	O75197-1.2	E1587W	Neutral	0.005
LRP5	O75197-1.2	E1587Y	Neutral	0.005
LRP5	O75197-1.2	D1588A	Neutral	0.0
LRP5	O75197-1.2	D1588C	Neutral	0.0
LRP5	O75197-1.2	D1588E	Neutral	0.0
LRP5	O75197-1.2	D1588F	Neutral	0.0
LRP5	O75197-1.2	D1588G	Neutral	0.0
LRP5	O75197-1.2	D1588H	Neutral	0.0
LRP5	O75197-1.2	D1588I	Neutral	0.0
LRP5	O75197-1.2	D1588K	Neutral	0.0
LRP5	O75197-1.2	D1588L	Neutral	0.0
LRP5	O75197-1.2	D1588M	Neutral	0.0
LRP5	O75197-1.2	D1588N	Neutral	0.0
LRP5	O75197-1.2	D1588P	Neutral	0.0
LRP5	O75197-1.2	D1588Q	Neutral	0.0
LRP5	O75197-1.2	D1588R	Neutral	0.0
LRP5	O75197-1.2	D1588S	Neutral	0.0
LRP5	O75197-1.2	D1588T	Neutral	0.0
LRP5	O75197-1.2	D1588V	Neutral	0.0
LRP5	O75197-1.2	D1588W	Neutral	0.0
LRP5	O75197-1.2	D1588Y	Neutral	0.0
LRP5	O75197-1.2	S1589A	Neutral	0.008
LRP5	O75197-1.2	S1589C	Neutral	0.037
LRP5	O75197-1.2	S1589D	Neutral	0.016
LRP5	O75197-1.2	S1589E	Neutral	0.017
LRP5	O75197-1.2	S1589F	Neutral	0.05
LRP5	O75197-1.2	S1589G	Neutral	0.029
LRP5	O75197-1.2	S1589H	Neutral	0.072
LRP5	O75197-1.2	S1589I	Neutral	0.05
LRP5	O75197-1.2	S1589K	Neutral	0.012
LRP5	O75197-1.2	S1589L	Neutral	0.055
LRP5	O75197-1.2	S1589M	Neutral	0.028
LRP5	O75197-1.2	S1589N	Neutral	0.006
LRP5	O75197-1.2	S1589P	Neutral	0.046
LRP5	O75197-1.2	S1589Q	Neutral	0.025
LRP5	O75197-1.2	S1589R	Neutral	0.035
LRP5	O75197-1.2	S1589T	Neutral	0.008
LRP5	O75197-1.2	S1589V	Neutral	0.084
LRP5	O75197-1.2	S1589W	Neutral	0.092
LRP5	O75197-1.2	S1589Y	Neutral	0.098
LRP5	O75197-1.2	C1590A	Neutral	0.022
LRP5	O75197-1.2	C1590D	Neutral	0.199
LRP5	O75197-1.2	C1590E	Neutral	0.453
LRP5	O75197-1.2	C1590F	Neutral	0.151
LRP5	O75197-1.2	C1590G	Neutral	0.319
LRP5	O75197-1.2	C1590H	Neutral	0.348
LRP5	O75197-1.2	C1590I	Neutral	0.055
LRP5	O75197-1.2	C1590K	Neutral	0.16
LRP5	O75197-1.2	C1590L	Neutral	0.06
LRP5	O75197-1.2	C1590M	Neutral	0.089
LRP5	O75197-1.2	C1590N	Neutral	0.223
LRP5	O75197-1.2	C1590P	Neutral	0.485
LRP5	O75197-1.2	C1590Q	Neutral	0.282
LRP5	O75197-1.2	C1590R	Neutral	0.155
LRP5	O75197-1.2	C1590S	Neutral	0.049
LRP5	O75197-1.2	C1590T	Neutral	0.063
LRP5	O75197-1.2	C1590V	Neutral	0.093
LRP5	O75197-1.2	C1590W	Neutral	0.101
LRP5	O75197-1.2	C1590Y	Neutral	0.262
LRP5	O75197-1.2	P1591A	Pathogenic	0.989
LRP5	O75197-1.2	P1591C	Pathogenic	0.999
LRP5	O75197-1.2	P1591D	Pathogenic	0.972
LRP5	O75197-1.2	P1591E	Pathogenic	0.974
LRP5	O75197-1.2	P1591F	Pathogenic	0.999
LRP5	O75197-1.2	P1591G	Pathogenic	0.995
LRP5	O75197-1.2	P1591H	Pathogenic	0.996
LRP5	O75197-1.2	P1591I	Pathogenic	0.998
LRP5	O75197-1.2	P1591K	Pathogenic	0.964
LRP5	O75197-1.2	P1591L	Pathogenic	0.998
LRP5	O75197-1.2	P1591M	Pathogenic	0.996
LRP5	O75197-1.2	P1591N	Pathogenic	0.992
LRP5	O75197-1.2	P1591Q	Pathogenic	0.982
LRP5	O75197-1.2	P1591R	Pathogenic	0.987
LRP5	O75197-1.2	P1591S	Pathogenic	0.985
LRP5	O75197-1.2	P1591T	Pathogenic	0.989
LRP5	O75197-1.2	P1591V	Pathogenic	0.996
LRP5	O75197-1.2	P1591W	Pathogenic	0.999
LRP5	O75197-1.2	P1591Y	Pathogenic	0.999
LRP5	O75197-1.2	P1592A	Pathogenic	0.966
LRP5	O75197-1.2	P1592C	Pathogenic	0.997
LRP5	O75197-1.2	P1592D	Pathogenic	0.918
LRP5	O75197-1.2	P1592E	Pathogenic	0.925
LRP5	O75197-1.2	P1592F	Pathogenic	0.998
LRP5	O75197-1.2	P1592G	Pathogenic	0.985
LRP5	O75197-1.2	P1592H	Pathogenic	0.987
LRP5	O75197-1.2	P1592I	Pathogenic	0.993
LRP5	O75197-1.2	P1592K	Pathogenic	0.896
LRP5	O75197-1.2	P1592L	Pathogenic	0.994
LRP5	O75197-1.2	P1592M	Pathogenic	0.987
LRP5	O75197-1.2	P1592N	Pathogenic	0.975
LRP5	O75197-1.2	P1592Q	Pathogenic	0.947
LRP5	O75197-1.2	P1592R	Pathogenic	0.962
LRP5	O75197-1.2	P1592S	Pathogenic	0.955
LRP5	O75197-1.2	P1592T	Pathogenic	0.966
LRP5	O75197-1.2	P1592V	Pathogenic	0.988
LRP5	O75197-1.2	P1592W	Pathogenic	0.996
LRP5	O75197-1.2	P1592Y	Pathogenic	0.997
LRP5	O75197-1.2	S1593A	Pathogenic	0.677
LRP5	O75197-1.2	S1593C	Pathogenic	0.913
LRP5	O75197-1.2	S1593D	Pathogenic	0.816
LRP5	O75197-1.2	S1593E	Pathogenic	0.829
LRP5	O75197-1.2	S1593F	Pathogenic	0.935
LRP5	O75197-1.2	S1593G	Pathogenic	0.891
LRP5	O75197-1.2	S1593H	Pathogenic	0.955
LRP5	O75197-1.2	S1593I	Pathogenic	0.935
LRP5	O75197-1.2	S1593K	Pathogenic	0.772
LRP5	O75197-1.2	S1593L	Pathogenic	0.941
LRP5	O75197-1.2	S1593M	Pathogenic	0.888
LRP5	O75197-1.2	S1593N	Pathogenic	0.626
LRP5	O75197-1.2	S1593P	Pathogenic	0.93
LRP5	O75197-1.2	S1593Q	Pathogenic	0.875
LRP5	O75197-1.2	S1593R	Pathogenic	0.909
LRP5	O75197-1.2	S1593T	Pathogenic	0.682
LRP5	O75197-1.2	S1593V	Pathogenic	0.962
LRP5	O75197-1.2	S1593W	Pathogenic	0.965
LRP5	O75197-1.2	S1593Y	Pathogenic	0.968
LRP5	O75197-1.2	P1594A	Pathogenic	0.968
LRP5	O75197-1.2	P1594C	Pathogenic	0.997
LRP5	O75197-1.2	P1594D	Pathogenic	0.922
LRP5	O75197-1.2	P1594E	Pathogenic	0.928
LRP5	O75197-1.2	P1594F	Pathogenic	0.998
LRP5	O75197-1.2	P1594G	Pathogenic	0.985
LRP5	O75197-1.2	P1594H	Pathogenic	0.987
LRP5	O75197-1.2	P1594I	Pathogenic	0.993
LRP5	O75197-1.2	P1594K	Pathogenic	0.9
LRP5	O75197-1.2	P1594L	Pathogenic	0.994
LRP5	O75197-1.2	P1594M	Pathogenic	0.988
LRP5	O75197-1.2	P1594N	Pathogenic	0.976
LRP5	O75197-1.2	P1594Q	Pathogenic	0.949
LRP5	O75197-1.2	P1594R	Pathogenic	0.964
LRP5	O75197-1.2	P1594S	Pathogenic	0.957
LRP5	O75197-1.2	P1594T	Pathogenic	0.967
LRP5	O75197-1.2	P1594V	Pathogenic	0.988
LRP5	O75197-1.2	P1594W	Pathogenic	0.996
LRP5	O75197-1.2	P1594Y	Pathogenic	0.997
LRP5	O75197-1.2	A1595C	Neutral	0.03
LRP5	O75197-1.2	A1595D	Neutral	0.165
LRP5	O75197-1.2	A1595E	Neutral	0.066
LRP5	O75197-1.2	A1595F	Neutral	0.113
LRP5	O75197-1.2	A1595G	Neutral	0.041
LRP5	O75197-1.2	A1595H	Neutral	0.297
LRP5	O75197-1.2	A1595I	Neutral	0.041
LRP5	O75197-1.2	A1595K	Neutral	0.047
LRP5	O75197-1.2	A1595L	Neutral	0.044
LRP5	O75197-1.2	A1595M	Neutral	0.066
LRP5	O75197-1.2	A1595N	Neutral	0.185
LRP5	O75197-1.2	A1595P	Neutral	0.105
LRP5	O75197-1.2	A1595Q	Neutral	0.093
LRP5	O75197-1.2	A1595R	Neutral	0.046
LRP5	O75197-1.2	A1595S	Neutral	0.014
LRP5	O75197-1.2	A1595T	Neutral	0.05
LRP5	O75197-1.2	A1595V	Neutral	0.024
LRP5	O75197-1.2	A1595W	Neutral	0.198
LRP5	O75197-1.2	A1595Y	Neutral	0.21
LRP5	O75197-1.2	T1596A	Pathogenic	0.668
LRP5	O75197-1.2	T1596C	Pathogenic	0.775
LRP5	O75197-1.2	T1596D	Pathogenic	0.726
LRP5	O75197-1.2	T1596E	Pathogenic	0.745
LRP5	O75197-1.2	T1596F	Pathogenic	0.828
LRP5	O75197-1.2	T1596G	Pathogenic	0.938
LRP5	O75197-1.2	T1596H	Pathogenic	0.946
LRP5	O75197-1.2	T1596I	Pathogenic	0.614
LRP5	O75197-1.2	T1596K	Pathogenic	0.672
LRP5	O75197-1.2	T1596L	Pathogenic	0.636
LRP5	O75197-1.2	T1596M	Pathogenic	0.726
LRP5	O75197-1.2	T1596N	Pathogenic	0.503
LRP5	O75197-1.2	T1596P	Pathogenic	0.815
LRP5	O75197-1.2	T1596Q	Pathogenic	0.808
LRP5	O75197-1.2	T1596R	Pathogenic	0.664
LRP5	O75197-1.2	T1596S	Neutral	0.349
LRP5	O75197-1.2	T1596V	Neutral	0.477
LRP5	O75197-1.2	T1596W	Pathogenic	0.753
LRP5	O75197-1.2	T1596Y	Pathogenic	0.909
LRP5	O75197-1.2	E1597A	Neutral	0.023
LRP5	O75197-1.2	E1597C	Neutral	0.274
LRP5	O75197-1.2	E1597D	Neutral	0.002
LRP5	O75197-1.2	E1597F	Neutral	0.057
LRP5	O75197-1.2	E1597G	Neutral	0.085
LRP5	O75197-1.2	E1597H	Neutral	0.01
LRP5	O75197-1.2	E1597I	Neutral	0.057
LRP5	O75197-1.2	E1597K	Neutral	0.004
LRP5	O75197-1.2	E1597L	Neutral	0.062
LRP5	O75197-1.2	E1597M	Neutral	0.032
LRP5	O75197-1.2	E1597N	Neutral	0.018
LRP5	O75197-1.2	E1597P	Neutral	0.017
LRP5	O75197-1.2	E1597Q	Neutral	0.001
LRP5	O75197-1.2	E1597R	Neutral	0.013
LRP5	O75197-1.2	E1597S	Neutral	0.011
LRP5	O75197-1.2	E1597T	Neutral	0.025
LRP5	O75197-1.2	E1597V	Neutral	0.033
LRP5	O75197-1.2	E1597W	Neutral	0.037
LRP5	O75197-1.2	E1597Y	Neutral	0.039
LRP5	O75197-1.2	R1598A	Neutral	0.004
LRP5	O75197-1.2	R1598C	Neutral	0.021
LRP5	O75197-1.2	R1598D	Neutral	0.033
LRP5	O75197-1.2	R1598E	Neutral	0.003
LRP5	O75197-1.2	R1598F	Neutral	0.011
LRP5	O75197-1.2	R1598G	Neutral	0.016
LRP5	O75197-1.2	R1598H	Neutral	0.002
LRP5	O75197-1.2	R1598I	Neutral	0.011
LRP5	O75197-1.2	R1598K	Neutral	0.001
LRP5	O75197-1.2	R1598L	Neutral	0.004
LRP5	O75197-1.2	R1598M	Neutral	0.002
LRP5	O75197-1.2	R1598N	Neutral	0.003
LRP5	O75197-1.2	R1598P	Neutral	0.009
LRP5	O75197-1.2	R1598Q	Neutral	0.001
LRP5	O75197-1.2	R1598S	Neutral	0.006
LRP5	O75197-1.2	R1598T	Neutral	0.004
LRP5	O75197-1.2	R1598V	Neutral	0.018
LRP5	O75197-1.2	R1598W	Neutral	0.007
LRP5	O75197-1.2	R1598Y	Neutral	0.008
LRP5	O75197-1.2	S1599A	Neutral	0.002
LRP5	O75197-1.2	S1599C	Neutral	0.009
LRP5	O75197-1.2	S1599D	Neutral	0.004
LRP5	O75197-1.2	S1599E	Neutral	0.004
LRP5	O75197-1.2	S1599F	Neutral	0.012
LRP5	O75197-1.2	S1599G	Neutral	0.007
LRP5	O75197-1.2	S1599H	Neutral	0.017
LRP5	O75197-1.2	S1599I	Neutral	0.012
LRP5	O75197-1.2	S1599K	Neutral	0.003
LRP5	O75197-1.2	S1599L	Neutral	0.013
LRP5	O75197-1.2	S1599M	Neutral	0.006
LRP5	O75197-1.2	S1599N	Neutral	0.001
LRP5	O75197-1.2	S1599P	Neutral	0.011
LRP5	O75197-1.2	S1599Q	Neutral	0.006
LRP5	O75197-1.2	S1599R	Neutral	0.008
LRP5	O75197-1.2	S1599T	Neutral	0.002
LRP5	O75197-1.2	S1599V	Neutral	0.02
LRP5	O75197-1.2	S1599W	Neutral	0.022
LRP5	O75197-1.2	S1599Y	Neutral	0.024
LRP5	O75197-1.2	Y1600A	Neutral	0.064
LRP5	O75197-1.2	Y1600C	Neutral	0.111
LRP5	O75197-1.2	Y1600D	Neutral	0.077
LRP5	O75197-1.2	Y1600E	Neutral	0.031
LRP5	O75197-1.2	Y1600F	Neutral	0.0
LRP5	O75197-1.2	Y1600G	Neutral	0.134
LRP5	O75197-1.2	Y1600H	Neutral	0.001
LRP5	O75197-1.2	Y1600I	Neutral	0.02
LRP5	O75197-1.2	Y1600K	Neutral	0.023
LRP5	O75197-1.2	Y1600L	Neutral	0.022
LRP5	O75197-1.2	Y1600M	Neutral	0.034
LRP5	O75197-1.2	Y1600N	Neutral	0.031
LRP5	O75197-1.2	Y1600P	Neutral	0.239
LRP5	O75197-1.2	Y1600Q	Neutral	0.015
LRP5	O75197-1.2	Y1600R	Neutral	0.023
LRP5	O75197-1.2	Y1600S	Neutral	0.049
LRP5	O75197-1.2	Y1600T	Neutral	0.064
LRP5	O75197-1.2	Y1600V	Neutral	0.033
LRP5	O75197-1.2	Y1600W	Neutral	0.0
LRP5	O75197-1.2	F1601A	Neutral	0.002
LRP5	O75197-1.2	F1601C	Neutral	0.003
LRP5	O75197-1.2	F1601D	Neutral	0.002
LRP5	O75197-1.2	F1601E	Neutral	0.002
LRP5	O75197-1.2	F1601G	Neutral	0.004
LRP5	O75197-1.2	F1601H	Neutral	0.001
LRP5	O75197-1.2	F1601I	Neutral	0.001
LRP5	O75197-1.2	F1601K	Neutral	0.002
LRP5	O75197-1.2	F1601L	Neutral	0.001
LRP5	O75197-1.2	F1601M	Neutral	0.0
LRP5	O75197-1.2	F1601N	Neutral	0.002
LRP5	O75197-1.2	F1601P	Neutral	0.023
LRP5	O75197-1.2	F1601Q	Neutral	0.003
LRP5	O75197-1.2	F1601R	Neutral	0.002
LRP5	O75197-1.2	F1601S	Neutral	0.001
LRP5	O75197-1.2	F1601T	Neutral	0.002
LRP5	O75197-1.2	F1601V	Neutral	0.001
LRP5	O75197-1.2	F1601W	Neutral	0.0
LRP5	O75197-1.2	F1601Y	Neutral	0.0
LRP5	O75197-1.2	H1602A	Neutral	0.022
LRP5	O75197-1.2	H1602C	Neutral	0.037
LRP5	O75197-1.2	H1602D	Neutral	0.004
LRP5	O75197-1.2	H1602E	Neutral	0.002
LRP5	O75197-1.2	H1602F	Neutral	0.002
LRP5	O75197-1.2	H1602G	Neutral	0.022
LRP5	O75197-1.2	H1602I	Neutral	0.019
LRP5	O75197-1.2	H1602K	Neutral	0.003
LRP5	O75197-1.2	H1602L	Neutral	0.021
LRP5	O75197-1.2	H1602M	Neutral	0.011
LRP5	O75197-1.2	H1602N	Neutral	0.001
LRP5	O75197-1.2	H1602P	Neutral	0.016
LRP5	O75197-1.2	H1602Q	Neutral	0.002
LRP5	O75197-1.2	H1602R	Neutral	0.001
LRP5	O75197-1.2	H1602S	Neutral	0.007
LRP5	O75197-1.2	H1602T	Neutral	0.024
LRP5	O75197-1.2	H1602V	Neutral	0.031
LRP5	O75197-1.2	H1602W	Neutral	0.004
LRP5	O75197-1.2	H1602Y	Neutral	0.0
LRP5	O75197-1.2	L1603A	Neutral	0.001
LRP5	O75197-1.2	L1603C	Neutral	0.002
LRP5	O75197-1.2	L1603D	Neutral	0.012
LRP5	O75197-1.2	L1603E	Neutral	0.005
LRP5	O75197-1.2	L1603F	Neutral	0.001
LRP5	O75197-1.2	L1603G	Neutral	0.022
LRP5	O75197-1.2	L1603H	Neutral	0.009
LRP5	O75197-1.2	L1603I	Neutral	0.0
LRP5	O75197-1.2	L1603K	Neutral	0.001
LRP5	O75197-1.2	L1603M	Neutral	0.0
LRP5	O75197-1.2	L1603N	Neutral	0.005
LRP5	O75197-1.2	L1603P	Neutral	0.015
LRP5	O75197-1.2	L1603Q	Neutral	0.002
LRP5	O75197-1.2	L1603R	Neutral	0.001
LRP5	O75197-1.2	L1603S	Neutral	0.002
LRP5	O75197-1.2	L1603T	Neutral	0.001
LRP5	O75197-1.2	L1603V	Neutral	0.0
LRP5	O75197-1.2	L1603W	Neutral	0.007
LRP5	O75197-1.2	L1603Y	Neutral	0.002
LRP5	O75197-1.2	F1604A	Neutral	0.001
LRP5	O75197-1.2	F1604C	Neutral	0.001
LRP5	O75197-1.2	F1604D	Neutral	0.001
LRP5	O75197-1.2	F1604E	Neutral	0.001
LRP5	O75197-1.2	F1604G	Neutral	0.002
LRP5	O75197-1.2	F1604H	Neutral	0.0
LRP5	O75197-1.2	F1604I	Neutral	0.0
LRP5	O75197-1.2	F1604K	Neutral	0.001
LRP5	O75197-1.2	F1604L	Neutral	0.0
LRP5	O75197-1.2	F1604M	Neutral	0.0
LRP5	O75197-1.2	F1604N	Neutral	0.001
LRP5	O75197-1.2	F1604P	Neutral	0.01
LRP5	O75197-1.2	F1604Q	Neutral	0.002
LRP5	O75197-1.2	F1604R	Neutral	0.001
LRP5	O75197-1.2	F1604S	Neutral	0.001
LRP5	O75197-1.2	F1604T	Neutral	0.001
LRP5	O75197-1.2	F1604V	Neutral	0.001
LRP5	O75197-1.2	F1604W	Neutral	0.0
LRP5	O75197-1.2	F1604Y	Neutral	0.0
LRP5	O75197-1.2	P1605A	Pathogenic	0.951
LRP5	O75197-1.2	P1605C	Pathogenic	0.995
LRP5	O75197-1.2	P1605D	Pathogenic	0.884
LRP5	O75197-1.2	P1605E	Pathogenic	0.893
LRP5	O75197-1.2	P1605F	Pathogenic	0.997
LRP5	O75197-1.2	P1605G	Pathogenic	0.977
LRP5	O75197-1.2	P1605H	Pathogenic	0.98
LRP5	O75197-1.2	P1605I	Pathogenic	0.99
LRP5	O75197-1.2	P1605K	Pathogenic	0.854
LRP5	O75197-1.2	P1605L	Pathogenic	0.991
LRP5	O75197-1.2	P1605M	Pathogenic	0.981
LRP5	O75197-1.2	P1605N	Pathogenic	0.964
LRP5	O75197-1.2	P1605Q	Pathogenic	0.923
LRP5	O75197-1.2	P1605R	Pathogenic	0.945
LRP5	O75197-1.2	P1605S	Pathogenic	0.935
LRP5	O75197-1.2	P1605T	Pathogenic	0.95
LRP5	O75197-1.2	P1605V	Pathogenic	0.982
LRP5	O75197-1.2	P1605W	Pathogenic	0.995
LRP5	O75197-1.2	P1605Y	Pathogenic	0.995
LRP5	O75197-1.2	P1606A	Pathogenic	0.934
LRP5	O75197-1.2	P1606C	Pathogenic	0.994
LRP5	O75197-1.2	P1606D	Pathogenic	0.849
LRP5	O75197-1.2	P1606E	Pathogenic	0.86
LRP5	O75197-1.2	P1606F	Pathogenic	0.995
LRP5	O75197-1.2	P1606G	Pathogenic	0.97
LRP5	O75197-1.2	P1606H	Pathogenic	0.973
LRP5	O75197-1.2	P1606I	Pathogenic	0.986
LRP5	O75197-1.2	P1606K	Pathogenic	0.811
LRP5	O75197-1.2	P1606L	Pathogenic	0.987
LRP5	O75197-1.2	P1606M	Pathogenic	0.975
LRP5	O75197-1.2	P1606N	Pathogenic	0.952
LRP5	O75197-1.2	P1606Q	Pathogenic	0.899
LRP5	O75197-1.2	P1606R	Pathogenic	0.927
LRP5	O75197-1.2	P1606S	Pathogenic	0.913
LRP5	O75197-1.2	P1606T	Pathogenic	0.933
LRP5	O75197-1.2	P1606V	Pathogenic	0.976
LRP5	O75197-1.2	P1606W	Pathogenic	0.993
LRP5	O75197-1.2	P1606Y	Pathogenic	0.993
LRP5	O75197-1.2	P1607A	Pathogenic	0.958
LRP5	O75197-1.2	P1607C	Pathogenic	0.996
LRP5	O75197-1.2	P1607D	Pathogenic	0.901
LRP5	O75197-1.2	P1607E	Pathogenic	0.908
LRP5	O75197-1.2	P1607F	Pathogenic	0.997
LRP5	O75197-1.2	P1607G	Pathogenic	0.981
LRP5	O75197-1.2	P1607H	Pathogenic	0.983
LRP5	O75197-1.2	P1607I	Pathogenic	0.991
LRP5	O75197-1.2	P1607K	Pathogenic	0.874
LRP5	O75197-1.2	P1607L	Pathogenic	0.992
LRP5	O75197-1.2	P1607M	Pathogenic	0.984
LRP5	O75197-1.2	P1607N	Pathogenic	0.97
LRP5	O75197-1.2	P1607Q	Pathogenic	0.935
LRP5	O75197-1.2	P1607R	Pathogenic	0.953
LRP5	O75197-1.2	P1607S	Pathogenic	0.945
LRP5	O75197-1.2	P1607T	Pathogenic	0.958
LRP5	O75197-1.2	P1607V	Pathogenic	0.985
LRP5	O75197-1.2	P1607W	Pathogenic	0.995
LRP5	O75197-1.2	P1607Y	Pathogenic	0.996
LRP5	O75197-1.2	P1608A	Pathogenic	0.942
LRP5	O75197-1.2	P1608C	Pathogenic	0.994
LRP5	O75197-1.2	P1608D	Pathogenic	0.865
LRP5	O75197-1.2	P1608E	Pathogenic	0.875
LRP5	O75197-1.2	P1608F	Pathogenic	0.996
LRP5	O75197-1.2	P1608G	Pathogenic	0.973
LRP5	O75197-1.2	P1608H	Pathogenic	0.977
LRP5	O75197-1.2	P1608I	Pathogenic	0.988
LRP5	O75197-1.2	P1608K	Pathogenic	0.831
LRP5	O75197-1.2	P1608L	Pathogenic	0.989
LRP5	O75197-1.2	P1608M	Pathogenic	0.978
LRP5	O75197-1.2	P1608N	Pathogenic	0.958
LRP5	O75197-1.2	P1608Q	Pathogenic	0.91
LRP5	O75197-1.2	P1608R	Pathogenic	0.935
LRP5	O75197-1.2	P1608S	Pathogenic	0.923
LRP5	O75197-1.2	P1608T	Pathogenic	0.941
LRP5	O75197-1.2	P1608V	Pathogenic	0.979
LRP5	O75197-1.2	P1608W	Pathogenic	0.994
LRP5	O75197-1.2	P1608Y	Pathogenic	0.994
LRP5	O75197-1.2	S1609A	Pathogenic	0.524
LRP5	O75197-1.2	S1609C	Pathogenic	0.847
LRP5	O75197-1.2	S1609D	Pathogenic	0.699
LRP5	O75197-1.2	S1609E	Pathogenic	0.718
LRP5	O75197-1.2	S1609F	Pathogenic	0.883
LRP5	O75197-1.2	S1609G	Pathogenic	0.811
LRP5	O75197-1.2	S1609H	Pathogenic	0.918
LRP5	O75197-1.2	S1609I	Pathogenic	0.883
LRP5	O75197-1.2	S1609K	Pathogenic	0.64
LRP5	O75197-1.2	S1609L	Pathogenic	0.893
LRP5	O75197-1.2	S1609M	Pathogenic	0.806
LRP5	O75197-1.2	S1609N	Neutral	0.468
LRP5	O75197-1.2	S1609P	Pathogenic	0.874
LRP5	O75197-1.2	S1609Q	Pathogenic	0.786
LRP5	O75197-1.2	S1609R	Pathogenic	0.84
LRP5	O75197-1.2	S1609T	Pathogenic	0.53
LRP5	O75197-1.2	S1609V	Pathogenic	0.93
LRP5	O75197-1.2	S1609W	Pathogenic	0.936
LRP5	O75197-1.2	S1609Y	Pathogenic	0.94
LRP5	O75197-1.2	P1610A	Pathogenic	0.988
LRP5	O75197-1.2	P1610C	Pathogenic	0.999
LRP5	O75197-1.2	P1610D	Pathogenic	0.969
LRP5	O75197-1.2	P1610E	Pathogenic	0.972
LRP5	O75197-1.2	P1610F	Pathogenic	0.999
LRP5	O75197-1.2	P1610G	Pathogenic	0.994
LRP5	O75197-1.2	P1610H	Pathogenic	0.995
LRP5	O75197-1.2	P1610I	Pathogenic	0.997
LRP5	O75197-1.2	P1610K	Pathogenic	0.96
LRP5	O75197-1.2	P1610L	Pathogenic	0.998
LRP5	O75197-1.2	P1610M	Pathogenic	0.995
LRP5	O75197-1.2	P1610N	Pathogenic	0.991
LRP5	O75197-1.2	P1610Q	Pathogenic	0.98
LRP5	O75197-1.2	P1610R	Pathogenic	0.986
LRP5	O75197-1.2	P1610S	Pathogenic	0.983
LRP5	O75197-1.2	P1610T	Pathogenic	0.987
LRP5	O75197-1.2	P1610V	Pathogenic	0.996
LRP5	O75197-1.2	P1610W	Pathogenic	0.999
LRP5	O75197-1.2	P1610Y	Pathogenic	0.999
LRP5	O75197-1.2	C1611A	Pathogenic	0.699
LRP5	O75197-1.2	C1611D	Pathogenic	0.962
LRP5	O75197-1.2	C1611E	Pathogenic	0.988
LRP5	O75197-1.2	C1611F	Pathogenic	0.948
LRP5	O75197-1.2	C1611G	Pathogenic	0.98
LRP5	O75197-1.2	C1611H	Pathogenic	0.982
LRP5	O75197-1.2	C1611I	Pathogenic	0.858
LRP5	O75197-1.2	C1611K	Pathogenic	0.951
LRP5	O75197-1.2	C1611L	Pathogenic	0.868
LRP5	O75197-1.2	C1611M	Pathogenic	0.909
LRP5	O75197-1.2	C1611N	Pathogenic	0.967
LRP5	O75197-1.2	C1611P	Pathogenic	0.99
LRP5	O75197-1.2	C1611Q	Pathogenic	0.976
LRP5	O75197-1.2	C1611R	Pathogenic	0.95
LRP5	O75197-1.2	C1611S	Pathogenic	0.84
LRP5	O75197-1.2	C1611T	Pathogenic	0.873
LRP5	O75197-1.2	C1611V	Pathogenic	0.913
LRP5	O75197-1.2	C1611W	Pathogenic	0.92
LRP5	O75197-1.2	C1611Y	Pathogenic	0.973
LRP5	O75197-1.2	T1612A	Pathogenic	0.512
LRP5	O75197-1.2	T1612C	Pathogenic	0.643
LRP5	O75197-1.2	T1612D	Pathogenic	0.581
LRP5	O75197-1.2	T1612E	Pathogenic	0.604
LRP5	O75197-1.2	T1612F	Pathogenic	0.716
LRP5	O75197-1.2	T1612G	Pathogenic	0.887
LRP5	O75197-1.2	T1612H	Pathogenic	0.901
LRP5	O75197-1.2	T1612I	Neutral	0.454
LRP5	O75197-1.2	T1612K	Pathogenic	0.517
LRP5	O75197-1.2	T1612L	Neutral	0.477
LRP5	O75197-1.2	T1612M	Pathogenic	0.581
LRP5	O75197-1.2	T1612N	Neutral	0.346
LRP5	O75197-1.2	T1612P	Pathogenic	0.696
LRP5	O75197-1.2	T1612Q	Pathogenic	0.688
LRP5	O75197-1.2	T1612R	Pathogenic	0.508
LRP5	O75197-1.2	T1612S	Neutral	0.219
LRP5	O75197-1.2	T1612V	Neutral	0.323
LRP5	O75197-1.2	T1612W	Pathogenic	0.614
LRP5	O75197-1.2	T1612Y	Pathogenic	0.839
LRP5	O75197-1.2	D1613A	Neutral	0.002
LRP5	O75197-1.2	D1613C	Neutral	0.004
LRP5	O75197-1.2	D1613E	Neutral	0.0
LRP5	O75197-1.2	D1613F	Neutral	0.002
LRP5	O75197-1.2	D1613G	Neutral	0.001
LRP5	O75197-1.2	D1613H	Neutral	0.001
LRP5	O75197-1.2	D1613I	Neutral	0.002
LRP5	O75197-1.2	D1613K	Neutral	0.001
LRP5	O75197-1.2	D1613L	Neutral	0.006
LRP5	O75197-1.2	D1613M	Neutral	0.003
LRP5	O75197-1.2	D1613N	Neutral	0.0
LRP5	O75197-1.2	D1613P	Neutral	0.001
LRP5	O75197-1.2	D1613Q	Neutral	0.0
LRP5	O75197-1.2	D1613R	Neutral	0.004
LRP5	O75197-1.2	D1613S	Neutral	0.0
LRP5	O75197-1.2	D1613T	Neutral	0.001
LRP5	O75197-1.2	D1613V	Neutral	0.003
LRP5	O75197-1.2	D1613W	Neutral	0.003
LRP5	O75197-1.2	D1613Y	Neutral	0.003
LRP5	O75197-1.2	S1614A	Neutral	0.0
LRP5	O75197-1.2	S1614C	Neutral	0.001
LRP5	O75197-1.2	S1614D	Neutral	0.001
LRP5	O75197-1.2	S1614E	Neutral	0.001
LRP5	O75197-1.2	S1614F	Neutral	0.002
LRP5	O75197-1.2	S1614G	Neutral	0.001
LRP5	O75197-1.2	S1614H	Neutral	0.003
LRP5	O75197-1.2	S1614I	Neutral	0.002
LRP5	O75197-1.2	S1614K	Neutral	0.0
LRP5	O75197-1.2	S1614L	Neutral	0.002
LRP5	O75197-1.2	S1614M	Neutral	0.001
LRP5	O75197-1.2	S1614N	Neutral	0.0
LRP5	O75197-1.2	S1614P	Neutral	0.002
LRP5	O75197-1.2	S1614Q	Neutral	0.001
LRP5	O75197-1.2	S1614R	Neutral	0.001
LRP5	O75197-1.2	S1614T	Neutral	0.0
LRP5	O75197-1.2	S1614V	Neutral	0.004
LRP5	O75197-1.2	S1614W	Neutral	0.004
LRP5	O75197-1.2	S1614Y	Neutral	0.004
LRP5	O75197-1.2	S1615A	Neutral	0.001
LRP5	O75197-1.2	S1615C	Neutral	0.003
LRP5	O75197-1.2	S1615D	Neutral	0.001
LRP5	O75197-1.2	S1615E	Neutral	0.001
LRP5	O75197-1.2	S1615F	Neutral	0.004
LRP5	O75197-1.2	S1615G	Neutral	0.002
LRP5	O75197-1.2	S1615H	Neutral	0.006
LRP5	O75197-1.2	S1615I	Neutral	0.004
LRP5	O75197-1.2	S1615K	Neutral	0.001
LRP5	O75197-1.2	S1615L	Neutral	0.004
LRP5	O75197-1.2	S1615M	Neutral	0.002
LRP5	O75197-1.2	S1615N	Neutral	0.0
LRP5	O75197-1.2	S1615P	Neutral	0.003
LRP5	O75197-1.2	S1615Q	Neutral	0.002
LRP5	O75197-1.2	S1615R	Neutral	0.003
LRP5	O75197-1.2	S1615T	Neutral	0.001
LRP5	O75197-1.2	S1615V	Neutral	0.007
LRP5	O75197-1.2	S1615W	Neutral	0.007
LRP5	O75197-1.2	S1615Y	Neutral	0.008
USH2A	O75445-1.3	M1A	Neutral	0.081
USH2A	O75445-1.3	M1C	Neutral	0.104
USH2A	O75445-1.3	M1D	Pathogenic	0.629
USH2A	O75445-1.3	M1E	Pathogenic	0.554
USH2A	O75445-1.3	M1F	Neutral	0.124
USH2A	O75445-1.3	M1G	Neutral	0.226
USH2A	O75445-1.3	M1H	Pathogenic	0.531
USH2A	O75445-1.3	M1I	Neutral	0.081
USH2A	O75445-1.3	M1K	Neutral	0.424
USH2A	O75445-1.3	M1L	Neutral	0.036
USH2A	O75445-1.3	M1N	Neutral	0.445
USH2A	O75445-1.3	M1P	Neutral	0.256
USH2A	O75445-1.3	M1Q	Neutral	0.185
USH2A	O75445-1.3	M1R	Neutral	0.328
USH2A	O75445-1.3	M1S	Neutral	0.113
USH2A	O75445-1.3	M1T	Neutral	0.173
USH2A	O75445-1.3	M1V	Neutral	0.035
USH2A	O75445-1.3	M1W	Neutral	0.142
USH2A	O75445-1.3	M1Y	Neutral	0.187
USH2A	O75445-1.3	N2A	Neutral	0.003
USH2A	O75445-1.3	N2C	Neutral	0.018
USH2A	O75445-1.3	N2D	Neutral	0.0
USH2A	O75445-1.3	N2E	Neutral	0.001
USH2A	O75445-1.3	N2F	Neutral	0.011
USH2A	O75445-1.3	N2G	Neutral	0.0
USH2A	O75445-1.3	N2H	Neutral	0.0
USH2A	O75445-1.3	N2I	Neutral	0.015
USH2A	O75445-1.3	N2K	Neutral	0.0
USH2A	O75445-1.3	N2L	Neutral	0.015
USH2A	O75445-1.3	N2M	Neutral	0.005
USH2A	O75445-1.3	N2P	Neutral	0.008
USH2A	O75445-1.3	N2Q	Neutral	0.001
USH2A	O75445-1.3	N2R	Neutral	0.0
USH2A	O75445-1.3	N2S	Neutral	0.0
USH2A	O75445-1.3	N2T	Neutral	0.001
USH2A	O75445-1.3	N2V	Neutral	0.021
USH2A	O75445-1.3	N2W	Neutral	0.013
USH2A	O75445-1.3	N2Y	Neutral	0.003
USH2A	O75445-1.3	C3A	Neutral	0.002
USH2A	O75445-1.3	C3D	Neutral	0.048
USH2A	O75445-1.3	C3E	Neutral	0.057
USH2A	O75445-1.3	C3F	Neutral	0.003
USH2A	O75445-1.3	C3G	Neutral	0.012
USH2A	O75445-1.3	C3H	Neutral	0.013
USH2A	O75445-1.3	C3I	Neutral	0.002
USH2A	O75445-1.3	C3K	Neutral	0.013
USH2A	O75445-1.3	C3L	Neutral	0.002
USH2A	O75445-1.3	C3M	Neutral	0.002
USH2A	O75445-1.3	C3N	Neutral	0.038
USH2A	O75445-1.3	C3P	Neutral	0.024
USH2A	O75445-1.3	C3Q	Neutral	0.018
USH2A	O75445-1.3	C3R	Neutral	0.009
USH2A	O75445-1.3	C3S	Neutral	0.005
USH2A	O75445-1.3	C3T	Neutral	0.005
USH2A	O75445-1.3	C3V	Neutral	0.003
USH2A	O75445-1.3	C3W	Neutral	0.002
USH2A	O75445-1.3	C3Y	Neutral	0.002
USH2A	O75445-1.3	P4A	Neutral	0.0
USH2A	O75445-1.3	P4C	Neutral	0.003
USH2A	O75445-1.3	P4D	Neutral	0.001
USH2A	O75445-1.3	P4E	Neutral	0.001
USH2A	O75445-1.3	P4F	Neutral	0.003
USH2A	O75445-1.3	P4G	Neutral	0.001
USH2A	O75445-1.3	P4H	Neutral	0.001
USH2A	O75445-1.3	P4I	Neutral	0.002
USH2A	O75445-1.3	P4K	Neutral	0.0
USH2A	O75445-1.3	P4L	Neutral	0.002
USH2A	O75445-1.3	P4M	Neutral	0.001
USH2A	O75445-1.3	P4N	Neutral	0.002
USH2A	O75445-1.3	P4Q	Neutral	0.0
USH2A	O75445-1.3	P4R	Neutral	0.001
USH2A	O75445-1.3	P4S	Neutral	0.001
USH2A	O75445-1.3	P4T	Neutral	0.001
USH2A	O75445-1.3	P4V	Neutral	0.001
USH2A	O75445-1.3	P4W	Neutral	0.002
USH2A	O75445-1.3	P4Y	Neutral	0.001
USH2A	O75445-1.3	V5A	Neutral	0.0
USH2A	O75445-1.3	V5C	Neutral	0.001
USH2A	O75445-1.3	V5D	Neutral	0.01
USH2A	O75445-1.3	V5E	Neutral	0.006
USH2A	O75445-1.3	V5F	Neutral	0.001
USH2A	O75445-1.3	V5G	Neutral	0.002
USH2A	O75445-1.3	V5H	Neutral	0.007
USH2A	O75445-1.3	V5I	Neutral	0.0
USH2A	O75445-1.3	V5K	Neutral	0.003
USH2A	O75445-1.3	V5L	Neutral	0.0
USH2A	O75445-1.3	V5M	Neutral	0.0
USH2A	O75445-1.3	V5N	Neutral	0.011
USH2A	O75445-1.3	V5P	Neutral	0.002
USH2A	O75445-1.3	V5Q	Neutral	0.004
USH2A	O75445-1.3	V5R	Neutral	0.004
USH2A	O75445-1.3	V5S	Neutral	0.002
USH2A	O75445-1.3	V5T	Neutral	0.001
USH2A	O75445-1.3	V5W	Neutral	0.002
USH2A	O75445-1.3	V5Y	Neutral	0.0
USH2A	O75445-1.3	L6A	Neutral	0.002
USH2A	O75445-1.3	L6C	Neutral	0.003
USH2A	O75445-1.3	L6D	Neutral	0.096
USH2A	O75445-1.3	L6E	Neutral	0.072
USH2A	O75445-1.3	L6F	Neutral	0.002
USH2A	O75445-1.3	L6G	Neutral	0.018
USH2A	O75445-1.3	L6H	Neutral	0.066
USH2A	O75445-1.3	L6I	Neutral	0.001
USH2A	O75445-1.3	L6K	Neutral	0.044
USH2A	O75445-1.3	L6M	Neutral	0.001
USH2A	O75445-1.3	L6N	Neutral	0.048
USH2A	O75445-1.3	L6P	Neutral	0.021
USH2A	O75445-1.3	L6Q	Neutral	0.032
USH2A	O75445-1.3	L6R	Neutral	0.03
USH2A	O75445-1.3	L6S	Neutral	0.008
USH2A	O75445-1.3	L6T	Neutral	0.006
USH2A	O75445-1.3	L6V	Neutral	0.001
USH2A	O75445-1.3	L6W	Neutral	0.006
USH2A	O75445-1.3	L6Y	Neutral	0.006
USH2A	O75445-1.3	S7A	Neutral	0.001
USH2A	O75445-1.3	S7C	Neutral	0.007
USH2A	O75445-1.3	S7D	Neutral	0.002
USH2A	O75445-1.3	S7E	Neutral	0.001
USH2A	O75445-1.3	S7F	Neutral	0.005
USH2A	O75445-1.3	S7G	Neutral	0.001
USH2A	O75445-1.3	S7H	Neutral	0.002
USH2A	O75445-1.3	S7I	Neutral	0.008
USH2A	O75445-1.3	S7K	Neutral	0.001
USH2A	O75445-1.3	S7L	Neutral	0.007
USH2A	O75445-1.3	S7M	Neutral	0.003
USH2A	O75445-1.3	S7N	Neutral	0.001
USH2A	O75445-1.3	S7P	Neutral	0.006
USH2A	O75445-1.3	S7Q	Neutral	0.001
USH2A	O75445-1.3	S7R	Neutral	0.001
USH2A	O75445-1.3	S7T	Neutral	0.001
USH2A	O75445-1.3	S7V	Neutral	0.01
USH2A	O75445-1.3	S7W	Neutral	0.006
USH2A	O75445-1.3	S7Y	Neutral	0.003
USH2A	O75445-1.3	L8A	Neutral	0.003
USH2A	O75445-1.3	L8C	Neutral	0.004
USH2A	O75445-1.3	L8D	Neutral	0.116
USH2A	O75445-1.3	L8E	Neutral	0.088
USH2A	O75445-1.3	L8F	Neutral	0.003
USH2A	O75445-1.3	L8G	Neutral	0.022
USH2A	O75445-1.3	L8H	Neutral	0.081
USH2A	O75445-1.3	L8I	Neutral	0.001
USH2A	O75445-1.3	L8K	Neutral	0.054
USH2A	O75445-1.3	L8M	Neutral	0.001
USH2A	O75445-1.3	L8N	Neutral	0.059
USH2A	O75445-1.3	L8P	Neutral	0.026
USH2A	O75445-1.3	L8Q	Neutral	0.039
USH2A	O75445-1.3	L8R	Neutral	0.036
USH2A	O75445-1.3	L8S	Neutral	0.01
USH2A	O75445-1.3	L8T	Neutral	0.007
USH2A	O75445-1.3	L8V	Neutral	0.001
USH2A	O75445-1.3	L8W	Neutral	0.008
USH2A	O75445-1.3	L8Y	Neutral	0.008
USH2A	O75445-1.3	G9A	Neutral	0.001
USH2A	O75445-1.3	G9C	Neutral	0.011
USH2A	O75445-1.3	G9D	Neutral	0.002
USH2A	O75445-1.3	G9E	Neutral	0.002
USH2A	O75445-1.3	G9F	Neutral	0.003
USH2A	O75445-1.3	G9H	Neutral	0.001
USH2A	O75445-1.3	G9I	Neutral	0.011
USH2A	O75445-1.3	G9K	Neutral	0.001
USH2A	O75445-1.3	G9L	Neutral	0.01
USH2A	O75445-1.3	G9M	Neutral	0.004
USH2A	O75445-1.3	G9N	Neutral	0.001
USH2A	O75445-1.3	G9P	Neutral	0.004
USH2A	O75445-1.3	G9Q	Neutral	0.001
USH2A	O75445-1.3	G9R	Neutral	0.001
USH2A	O75445-1.3	G9S	Neutral	0.001
USH2A	O75445-1.3	G9T	Neutral	0.003
USH2A	O75445-1.3	G9V	Neutral	0.006
USH2A	O75445-1.3	G9W	Neutral	0.001
USH2A	O75445-1.3	G9Y	Neutral	0.002
USH2A	O75445-1.3	S10A	Neutral	0.0
USH2A	O75445-1.3	S10C	Neutral	0.0
USH2A	O75445-1.3	S10D	Neutral	0.0
USH2A	O75445-1.3	S10E	Neutral	0.0
USH2A	O75445-1.3	S10F	Neutral	0.0
USH2A	O75445-1.3	S10G	Neutral	0.0
USH2A	O75445-1.3	S10H	Neutral	0.0
USH2A	O75445-1.3	S10I	Neutral	0.0
USH2A	O75445-1.3	S10K	Neutral	0.0
USH2A	O75445-1.3	S10L	Neutral	0.0
USH2A	O75445-1.3	S10M	Neutral	0.0
USH2A	O75445-1.3	S10N	Neutral	0.0
USH2A	O75445-1.3	S10P	Neutral	0.0
USH2A	O75445-1.3	S10Q	Neutral	0.0
USH2A	O75445-1.3	S10R	Neutral	0.0
USH2A	O75445-1.3	S10T	Neutral	0.0
USH2A	O75445-1.3	S10V	Neutral	0.0
USH2A	O75445-1.3	S10W	Neutral	0.0
USH2A	O75445-1.3	S10Y	Neutral	0.0
USH2A	O75445-1.3	G11A	Neutral	0.002
USH2A	O75445-1.3	G11C	Neutral	0.014
USH2A	O75445-1.3	G11D	Neutral	0.002
USH2A	O75445-1.3	G11E	Neutral	0.002
USH2A	O75445-1.3	G11F	Neutral	0.004
USH2A	O75445-1.3	G11H	Neutral	0.001
USH2A	O75445-1.3	G11I	Neutral	0.014
USH2A	O75445-1.3	G11K	Neutral	0.001
USH2A	O75445-1.3	G11L	Neutral	0.013
USH2A	O75445-1.3	G11M	Neutral	0.005
USH2A	O75445-1.3	G11N	Neutral	0.001
USH2A	O75445-1.3	G11P	Neutral	0.005
USH2A	O75445-1.3	G11Q	Neutral	0.002
USH2A	O75445-1.3	G11R	Neutral	0.001
USH2A	O75445-1.3	G11S	Neutral	0.001
USH2A	O75445-1.3	G11T	Neutral	0.003
USH2A	O75445-1.3	G11V	Neutral	0.008
USH2A	O75445-1.3	G11W	Neutral	0.001
USH2A	O75445-1.3	G11Y	Neutral	0.002
USH2A	O75445-1.3	F12A	Neutral	0.03
USH2A	O75445-1.3	F12C	Neutral	0.04
USH2A	O75445-1.3	F12D	Neutral	0.209
USH2A	O75445-1.3	F12E	Neutral	0.306
USH2A	O75445-1.3	F12G	Neutral	0.043
USH2A	O75445-1.3	F12H	Neutral	0.071
USH2A	O75445-1.3	F12I	Neutral	0.018
USH2A	O75445-1.3	F12K	Pathogenic	0.547
USH2A	O75445-1.3	F12L	Neutral	0.018
USH2A	O75445-1.3	F12M	Neutral	0.023
USH2A	O75445-1.3	F12N	Neutral	0.222
USH2A	O75445-1.3	F12P	Neutral	0.218
USH2A	O75445-1.3	F12Q	Neutral	0.296
USH2A	O75445-1.3	F12R	Neutral	0.445
USH2A	O75445-1.3	F12S	Neutral	0.043
USH2A	O75445-1.3	F12T	Neutral	0.069
USH2A	O75445-1.3	F12V	Neutral	0.029
USH2A	O75445-1.3	F12W	Neutral	0.006
USH2A	O75445-1.3	F12Y	Neutral	0.003
USH2A	O75445-1.3	L13A	Neutral	0.01
USH2A	O75445-1.3	L13C	Neutral	0.014
USH2A	O75445-1.3	L13D	Neutral	0.316
USH2A	O75445-1.3	L13E	Neutral	0.253
USH2A	O75445-1.3	L13F	Neutral	0.01
USH2A	O75445-1.3	L13G	Neutral	0.074
USH2A	O75445-1.3	L13H	Neutral	0.236
USH2A	O75445-1.3	L13I	Neutral	0.003
USH2A	O75445-1.3	L13K	Neutral	0.167
USH2A	O75445-1.3	L13M	Neutral	0.003
USH2A	O75445-1.3	L13N	Neutral	0.18
USH2A	O75445-1.3	L13P	Neutral	0.086
USH2A	O75445-1.3	L13Q	Neutral	0.124
USH2A	O75445-1.3	L13R	Neutral	0.117
USH2A	O75445-1.3	L13S	Neutral	0.033
USH2A	O75445-1.3	L13T	Neutral	0.024
USH2A	O75445-1.3	L13V	Neutral	0.004
USH2A	O75445-1.3	L13W	Neutral	0.027
USH2A	O75445-1.3	L13Y	Neutral	0.027
USH2A	O75445-1.3	F14A	Neutral	0.009
USH2A	O75445-1.3	F14C	Neutral	0.012
USH2A	O75445-1.3	F14D	Neutral	0.073
USH2A	O75445-1.3	F14E	Neutral	0.116
USH2A	O75445-1.3	F14G	Neutral	0.013
USH2A	O75445-1.3	F14H	Neutral	0.023
USH2A	O75445-1.3	F14I	Neutral	0.005
USH2A	O75445-1.3	F14K	Neutral	0.266
USH2A	O75445-1.3	F14L	Neutral	0.006
USH2A	O75445-1.3	F14M	Neutral	0.007
USH2A	O75445-1.3	F14N	Neutral	0.079
USH2A	O75445-1.3	F14P	Neutral	0.077
USH2A	O75445-1.3	F14Q	Neutral	0.112
USH2A	O75445-1.3	F14R	Neutral	0.194
USH2A	O75445-1.3	F14S	Neutral	0.013
USH2A	O75445-1.3	F14T	Neutral	0.022
USH2A	O75445-1.3	F14V	Neutral	0.009
USH2A	O75445-1.3	F14W	Neutral	0.002
USH2A	O75445-1.3	F14Y	Neutral	0.001
USH2A	O75445-1.3	Q15A	Neutral	0.0
USH2A	O75445-1.3	Q15C	Neutral	0.006
USH2A	O75445-1.3	Q15D	Neutral	0.0
USH2A	O75445-1.3	Q15E	Neutral	0.0
USH2A	O75445-1.3	Q15F	Neutral	0.012
USH2A	O75445-1.3	Q15G	Neutral	0.001
USH2A	O75445-1.3	Q15H	Neutral	0.001
USH2A	O75445-1.3	Q15I	Neutral	0.017
USH2A	O75445-1.3	Q15K	Neutral	0.0
USH2A	O75445-1.3	Q15L	Neutral	0.007
USH2A	O75445-1.3	Q15M	Neutral	0.001
USH2A	O75445-1.3	Q15N	Neutral	0.0
USH2A	O75445-1.3	Q15P	Neutral	0.001
USH2A	O75445-1.3	Q15R	Neutral	0.0
USH2A	O75445-1.3	Q15S	Neutral	0.0
USH2A	O75445-1.3	Q15T	Neutral	0.001
USH2A	O75445-1.3	Q15V	Neutral	0.006
USH2A	O75445-1.3	Q15W	Neutral	0.003
USH2A	O75445-1.3	Q15Y	Neutral	0.001
USH2A	O75445-1.3	V16A	Neutral	0.001
USH2A	O75445-1.3	V16C	Neutral	0.002
USH2A	O75445-1.3	V16D	Neutral	0.031
USH2A	O75445-1.3	V16E	Neutral	0.018
USH2A	O75445-1.3	V16F	Neutral	0.002
USH2A	O75445-1.3	V16G	Neutral	0.005
USH2A	O75445-1.3	V16H	Neutral	0.021
USH2A	O75445-1.3	V16I	Neutral	0.0
USH2A	O75445-1.3	V16K	Neutral	0.009
USH2A	O75445-1.3	V16L	Neutral	0.0
USH2A	O75445-1.3	V16M	Neutral	0.0
USH2A	O75445-1.3	V16N	Neutral	0.033
USH2A	O75445-1.3	V16P	Neutral	0.006
USH2A	O75445-1.3	V16Q	Neutral	0.012
USH2A	O75445-1.3	V16R	Neutral	0.014
USH2A	O75445-1.3	V16S	Neutral	0.005
USH2A	O75445-1.3	V16T	Neutral	0.002
USH2A	O75445-1.3	V16W	Neutral	0.005
USH2A	O75445-1.3	V16Y	Neutral	0.001
USH2A	O75445-1.3	I17A	Neutral	0.003
USH2A	O75445-1.3	I17C	Neutral	0.005
USH2A	O75445-1.3	I17D	Neutral	0.063
USH2A	O75445-1.3	I17E	Neutral	0.1
USH2A	O75445-1.3	I17F	Neutral	0.003
USH2A	O75445-1.3	I17G	Neutral	0.025
USH2A	O75445-1.3	I17H	Neutral	0.092
USH2A	O75445-1.3	I17K	Neutral	0.131
USH2A	O75445-1.3	I17L	Neutral	0.001
USH2A	O75445-1.3	I17M	Neutral	0.003
USH2A	O75445-1.3	I17N	Neutral	0.067
USH2A	O75445-1.3	I17P	Neutral	0.03
USH2A	O75445-1.3	I17Q	Neutral	0.096
USH2A	O75445-1.3	I17R	Neutral	0.091
USH2A	O75445-1.3	I17S	Neutral	0.011
USH2A	O75445-1.3	I17T	Neutral	0.008
USH2A	O75445-1.3	I17V	Neutral	0.0
USH2A	O75445-1.3	I17W	Neutral	0.019
USH2A	O75445-1.3	I17Y	Neutral	0.009
USH2A	O75445-1.3	E18A	Neutral	0.002
USH2A	O75445-1.3	E18C	Neutral	0.061
USH2A	O75445-1.3	E18D	Neutral	0.0
USH2A	O75445-1.3	E18F	Neutral	0.037
USH2A	O75445-1.3	E18G	Neutral	0.002
USH2A	O75445-1.3	E18H	Neutral	0.002
USH2A	O75445-1.3	E18I	Neutral	0.053
USH2A	O75445-1.3	E18K	Neutral	0.001
USH2A	O75445-1.3	E18L	Neutral	0.05
USH2A	O75445-1.3	E18M	Neutral	0.018
USH2A	O75445-1.3	E18N	Neutral	0.002
USH2A	O75445-1.3	E18P	Neutral	0.005
USH2A	O75445-1.3	E18Q	Neutral	0.0
USH2A	O75445-1.3	E18R	Neutral	0.001
USH2A	O75445-1.3	E18S	Neutral	0.001
USH2A	O75445-1.3	E18T	Neutral	0.005
USH2A	O75445-1.3	E18V	Neutral	0.025
USH2A	O75445-1.3	E18W	Neutral	0.019
USH2A	O75445-1.3	E18Y	Neutral	0.009
USH2A	O75445-1.3	M19A	Neutral	0.001
USH2A	O75445-1.3	M19C	Neutral	0.002
USH2A	O75445-1.3	M19D	Neutral	0.026
USH2A	O75445-1.3	M19E	Neutral	0.019
USH2A	O75445-1.3	M19F	Neutral	0.002
USH2A	O75445-1.3	M19G	Neutral	0.005
USH2A	O75445-1.3	M19H	Neutral	0.018
USH2A	O75445-1.3	M19I	Neutral	0.001
USH2A	O75445-1.3	M19K	Neutral	0.011
USH2A	O75445-1.3	M19L	Neutral	0.001
USH2A	O75445-1.3	M19N	Neutral	0.013
USH2A	O75445-1.3	M19P	Neutral	0.005
USH2A	O75445-1.3	M19Q	Neutral	0.004
USH2A	O75445-1.3	M19R	Neutral	0.008
USH2A	O75445-1.3	M19S	Neutral	0.002
USH2A	O75445-1.3	M19T	Neutral	0.003
USH2A	O75445-1.3	M19V	Neutral	0.001
USH2A	O75445-1.3	M19W	Neutral	0.003
USH2A	O75445-1.3	M19Y	Neutral	0.004
USH2A	O75445-1.3	L20A	Neutral	0.005
USH2A	O75445-1.3	L20C	Neutral	0.006
USH2A	O75445-1.3	L20D	Neutral	0.167
USH2A	O75445-1.3	L20E	Neutral	0.128
USH2A	O75445-1.3	L20F	Neutral	0.005
USH2A	O75445-1.3	L20G	Neutral	0.033
USH2A	O75445-1.3	L20H	Neutral	0.118
USH2A	O75445-1.3	L20I	Neutral	0.001
USH2A	O75445-1.3	L20K	Neutral	0.08
USH2A	O75445-1.3	L20M	Neutral	0.002
USH2A	O75445-1.3	L20N	Neutral	0.086
USH2A	O75445-1.3	L20P	Neutral	0.039
USH2A	O75445-1.3	L20Q	Neutral	0.058
USH2A	O75445-1.3	L20R	Neutral	0.054
USH2A	O75445-1.3	L20S	Neutral	0.015
USH2A	O75445-1.3	L20T	Neutral	0.011
USH2A	O75445-1.3	L20V	Neutral	0.002
USH2A	O75445-1.3	L20W	Neutral	0.012
USH2A	O75445-1.3	L20Y	Neutral	0.012
USH2A	O75445-1.3	I21A	Neutral	0.008
USH2A	O75445-1.3	I21C	Neutral	0.01
USH2A	O75445-1.3	I21D	Neutral	0.129
USH2A	O75445-1.3	I21E	Neutral	0.198
USH2A	O75445-1.3	I21F	Neutral	0.007
USH2A	O75445-1.3	I21G	Neutral	0.055
USH2A	O75445-1.3	I21H	Neutral	0.184
USH2A	O75445-1.3	I21K	Neutral	0.251
USH2A	O75445-1.3	I21L	Neutral	0.002
USH2A	O75445-1.3	I21M	Neutral	0.006
USH2A	O75445-1.3	I21N	Neutral	0.138
USH2A	O75445-1.3	I21P	Neutral	0.064
USH2A	O75445-1.3	I21Q	Neutral	0.191
USH2A	O75445-1.3	I21R	Neutral	0.182
USH2A	O75445-1.3	I21S	Neutral	0.025
USH2A	O75445-1.3	I21T	Neutral	0.018
USH2A	O75445-1.3	I21V	Neutral	0.001
USH2A	O75445-1.3	I21W	Neutral	0.041
USH2A	O75445-1.3	I21Y	Neutral	0.02
USH2A	O75445-1.3	F22A	Neutral	0.006
USH2A	O75445-1.3	F22C	Neutral	0.007
USH2A	O75445-1.3	F22D	Neutral	0.046
USH2A	O75445-1.3	F22E	Neutral	0.075
USH2A	O75445-1.3	F22G	Neutral	0.008
USH2A	O75445-1.3	F22H	Neutral	0.014
USH2A	O75445-1.3	F22I	Neutral	0.003
USH2A	O75445-1.3	F22K	Neutral	0.181
USH2A	O75445-1.3	F22L	Neutral	0.003
USH2A	O75445-1.3	F22M	Neutral	0.004
USH2A	O75445-1.3	F22N	Neutral	0.05
USH2A	O75445-1.3	F22P	Neutral	0.049
USH2A	O75445-1.3	F22Q	Neutral	0.072
USH2A	O75445-1.3	F22R	Neutral	0.128
USH2A	O75445-1.3	F22S	Neutral	0.008
USH2A	O75445-1.3	F22T	Neutral	0.013
USH2A	O75445-1.3	F22V	Neutral	0.005
USH2A	O75445-1.3	F22W	Neutral	0.001
USH2A	O75445-1.3	F22Y	Neutral	0.0
USH2A	O75445-1.3	A23C	Neutral	0.001
USH2A	O75445-1.3	A23D	Neutral	0.006
USH2A	O75445-1.3	A23E	Neutral	0.001
USH2A	O75445-1.3	A23F	Neutral	0.002
USH2A	O75445-1.3	A23G	Neutral	0.001
USH2A	O75445-1.3	A23H	Neutral	0.001
USH2A	O75445-1.3	A23I	Neutral	0.001
USH2A	O75445-1.3	A23K	Neutral	0.001
USH2A	O75445-1.3	A23L	Neutral	0.001
USH2A	O75445-1.3	A23M	Neutral	0.001
USH2A	O75445-1.3	A23N	Neutral	0.004
USH2A	O75445-1.3	A23P	Neutral	0.002
USH2A	O75445-1.3	A23Q	Neutral	0.001
USH2A	O75445-1.3	A23R	Neutral	0.0
USH2A	O75445-1.3	A23S	Neutral	0.001
USH2A	O75445-1.3	A23T	Neutral	0.001
USH2A	O75445-1.3	A23V	Neutral	0.001
USH2A	O75445-1.3	A23W	Neutral	0.002
USH2A	O75445-1.3	A23Y	Neutral	0.001
USH2A	O75445-1.3	Y24A	Neutral	0.01
USH2A	O75445-1.3	Y24C	Neutral	0.013
USH2A	O75445-1.3	Y24D	Neutral	0.078
USH2A	O75445-1.3	Y24E	Neutral	0.058
USH2A	O75445-1.3	Y24F	Neutral	0.002
USH2A	O75445-1.3	Y24G	Neutral	0.014
USH2A	O75445-1.3	Y24H	Neutral	0.002
USH2A	O75445-1.3	Y24I	Neutral	0.029
USH2A	O75445-1.3	Y24K	Neutral	0.145
USH2A	O75445-1.3	Y24L	Neutral	0.028
USH2A	O75445-1.3	Y24M	Neutral	0.022
USH2A	O75445-1.3	Y24N	Neutral	0.038
USH2A	O75445-1.3	Y24P	Neutral	0.038
USH2A	O75445-1.3	Y24Q	Neutral	0.025
USH2A	O75445-1.3	Y24R	Neutral	0.142
USH2A	O75445-1.3	Y24S	Neutral	0.014
USH2A	O75445-1.3	Y24T	Neutral	0.023
USH2A	O75445-1.3	Y24V	Neutral	0.012
USH2A	O75445-1.3	Y24W	Neutral	0.003
USH2A	O75445-1.3	F25A	Neutral	0.002
USH2A	O75445-1.3	F25C	Neutral	0.003
USH2A	O75445-1.3	F25D	Neutral	0.016
USH2A	O75445-1.3	F25E	Neutral	0.027
USH2A	O75445-1.3	F25G	Neutral	0.003
USH2A	O75445-1.3	F25H	Neutral	0.005
USH2A	O75445-1.3	F25I	Neutral	0.001
USH2A	O75445-1.3	F25K	Neutral	0.07
USH2A	O75445-1.3	F25L	Neutral	0.001
USH2A	O75445-1.3	F25M	Neutral	0.001
USH2A	O75445-1.3	F25N	Neutral	0.017
USH2A	O75445-1.3	F25P	Neutral	0.017
USH2A	O75445-1.3	F25Q	Neutral	0.026
USH2A	O75445-1.3	F25R	Neutral	0.048
USH2A	O75445-1.3	F25S	Neutral	0.003
USH2A	O75445-1.3	F25T	Neutral	0.005
USH2A	O75445-1.3	F25V	Neutral	0.002
USH2A	O75445-1.3	F25W	Neutral	0.0
USH2A	O75445-1.3	F25Y	Neutral	0.0
USH2A	O75445-1.3	A26C	Neutral	0.001
USH2A	O75445-1.3	A26D	Neutral	0.005
USH2A	O75445-1.3	A26E	Neutral	0.001
USH2A	O75445-1.3	A26F	Neutral	0.002
USH2A	O75445-1.3	A26G	Neutral	0.001
USH2A	O75445-1.3	A26H	Neutral	0.001
USH2A	O75445-1.3	A26I	Neutral	0.001
USH2A	O75445-1.3	A26K	Neutral	0.001
USH2A	O75445-1.3	A26L	Neutral	0.001
USH2A	O75445-1.3	A26M	Neutral	0.001
USH2A	O75445-1.3	A26N	Neutral	0.004
USH2A	O75445-1.3	A26P	Neutral	0.002
USH2A	O75445-1.3	A26Q	Neutral	0.001
USH2A	O75445-1.3	A26R	Neutral	0.0
USH2A	O75445-1.3	A26S	Neutral	0.001
USH2A	O75445-1.3	A26T	Neutral	0.001
USH2A	O75445-1.3	A26V	Neutral	0.001
USH2A	O75445-1.3	A26W	Neutral	0.002
USH2A	O75445-1.3	A26Y	Neutral	0.001
USH2A	O75445-1.3	S27A	Neutral	0.001
USH2A	O75445-1.3	S27C	Neutral	0.005
USH2A	O75445-1.3	S27D	Neutral	0.001
USH2A	O75445-1.3	S27E	Neutral	0.001
USH2A	O75445-1.3	S27F	Neutral	0.003
USH2A	O75445-1.3	S27G	Neutral	0.001
USH2A	O75445-1.3	S27H	Neutral	0.001
USH2A	O75445-1.3	S27I	Neutral	0.005
USH2A	O75445-1.3	S27K	Neutral	0.0
USH2A	O75445-1.3	S27L	Neutral	0.004
USH2A	O75445-1.3	S27M	Neutral	0.002
USH2A	O75445-1.3	S27N	Neutral	0.001
USH2A	O75445-1.3	S27P	Neutral	0.004
USH2A	O75445-1.3	S27Q	Neutral	0.001
USH2A	O75445-1.3	S27R	Neutral	0.001
USH2A	O75445-1.3	S27T	Neutral	0.0
USH2A	O75445-1.3	S27V	Neutral	0.006
USH2A	O75445-1.3	S27W	Neutral	0.004
USH2A	O75445-1.3	S27Y	Neutral	0.002
USH2A	O75445-1.3	I28A	Neutral	0.001
USH2A	O75445-1.3	I28C	Neutral	0.001
USH2A	O75445-1.3	I28D	Neutral	0.014
USH2A	O75445-1.3	I28E	Neutral	0.024
USH2A	O75445-1.3	I28F	Neutral	0.001
USH2A	O75445-1.3	I28G	Neutral	0.006
USH2A	O75445-1.3	I28H	Neutral	0.022
USH2A	O75445-1.3	I28K	Neutral	0.032
USH2A	O75445-1.3	I28L	Neutral	0.0
USH2A	O75445-1.3	I28M	Neutral	0.001
USH2A	O75445-1.3	I28N	Neutral	0.015
USH2A	O75445-1.3	I28P	Neutral	0.007
USH2A	O75445-1.3	I28Q	Neutral	0.023
USH2A	O75445-1.3	I28R	Neutral	0.021
USH2A	O75445-1.3	I28S	Neutral	0.002
USH2A	O75445-1.3	I28T	Neutral	0.002
USH2A	O75445-1.3	I28V	Neutral	0.0
USH2A	O75445-1.3	I28W	Neutral	0.004
USH2A	O75445-1.3	I28Y	Neutral	0.002
USH2A	O75445-1.3	S29A	Neutral	0.0
USH2A	O75445-1.3	S29C	Neutral	0.001
USH2A	O75445-1.3	S29D	Neutral	0.0
USH2A	O75445-1.3	S29E	Neutral	0.0
USH2A	O75445-1.3	S29F	Neutral	0.001
USH2A	O75445-1.3	S29G	Neutral	0.0
USH2A	O75445-1.3	S29H	Neutral	0.0
USH2A	O75445-1.3	S29I	Neutral	0.001
USH2A	O75445-1.3	S29K	Neutral	0.0
USH2A	O75445-1.3	S29L	Neutral	0.001
USH2A	O75445-1.3	S29M	Neutral	0.0
USH2A	O75445-1.3	S29N	Neutral	0.0
USH2A	O75445-1.3	S29P	Neutral	0.001
USH2A	O75445-1.3	S29Q	Neutral	0.0
USH2A	O75445-1.3	S29R	Neutral	0.0
USH2A	O75445-1.3	S29T	Neutral	0.0
USH2A	O75445-1.3	S29V	Neutral	0.002
USH2A	O75445-1.3	S29W	Neutral	0.001
USH2A	O75445-1.3	S29Y	Neutral	0.0
USH2A	O75445-1.3	L30A	Neutral	0.004
USH2A	O75445-1.3	L30C	Neutral	0.005
USH2A	O75445-1.3	L30D	Neutral	0.155
USH2A	O75445-1.3	L30E	Neutral	0.118
USH2A	O75445-1.3	L30F	Neutral	0.004
USH2A	O75445-1.3	L30G	Neutral	0.03
USH2A	O75445-1.3	L30H	Neutral	0.109
USH2A	O75445-1.3	L30I	Neutral	0.001
USH2A	O75445-1.3	L30K	Neutral	0.074
USH2A	O75445-1.3	L30M	Neutral	0.001
USH2A	O75445-1.3	L30N	Neutral	0.08
USH2A	O75445-1.3	L30P	Neutral	0.036
USH2A	O75445-1.3	L30Q	Neutral	0.053
USH2A	O75445-1.3	L30R	Neutral	0.05
USH2A	O75445-1.3	L30S	Neutral	0.014
USH2A	O75445-1.3	L30T	Neutral	0.01
USH2A	O75445-1.3	L30V	Neutral	0.002
USH2A	O75445-1.3	L30W	Neutral	0.011
USH2A	O75445-1.3	L30Y	Neutral	0.011
USH2A	O75445-1.3	T31A	Neutral	0.0
USH2A	O75445-1.3	T31C	Neutral	0.001
USH2A	O75445-1.3	T31D	Neutral	0.002
USH2A	O75445-1.3	T31E	Neutral	0.001
USH2A	O75445-1.3	T31F	Neutral	0.001
USH2A	O75445-1.3	T31G	Neutral	0.001
USH2A	O75445-1.3	T31H	Neutral	0.001
USH2A	O75445-1.3	T31I	Neutral	0.001
USH2A	O75445-1.3	T31K	Neutral	0.001
USH2A	O75445-1.3	T31L	Neutral	0.001
USH2A	O75445-1.3	T31M	Neutral	0.001
USH2A	O75445-1.3	T31N	Neutral	0.001
USH2A	O75445-1.3	T31P	Neutral	0.001
USH2A	O75445-1.3	T31Q	Neutral	0.001
USH2A	O75445-1.3	T31R	Neutral	0.0
USH2A	O75445-1.3	T31S	Neutral	0.0
USH2A	O75445-1.3	T31V	Neutral	0.001
USH2A	O75445-1.3	T31W	Neutral	0.001
USH2A	O75445-1.3	T31Y	Neutral	0.001
USH2A	O75445-1.3	E32A	Neutral	0.003
USH2A	O75445-1.3	E32C	Neutral	0.097
USH2A	O75445-1.3	E32D	Neutral	0.0
USH2A	O75445-1.3	E32F	Neutral	0.06
USH2A	O75445-1.3	E32G	Neutral	0.004
USH2A	O75445-1.3	E32H	Neutral	0.004
USH2A	O75445-1.3	E32I	Neutral	0.084
USH2A	O75445-1.3	E32K	Neutral	0.001
USH2A	O75445-1.3	E32L	Neutral	0.08
USH2A	O75445-1.3	E32M	Neutral	0.029
USH2A	O75445-1.3	E32N	Neutral	0.002
USH2A	O75445-1.3	E32P	Neutral	0.009
USH2A	O75445-1.3	E32Q	Neutral	0.001
USH2A	O75445-1.3	E32R	Neutral	0.001
USH2A	O75445-1.3	E32S	Neutral	0.002
USH2A	O75445-1.3	E32T	Neutral	0.008
USH2A	O75445-1.3	E32V	Neutral	0.041
USH2A	O75445-1.3	E32W	Neutral	0.032
USH2A	O75445-1.3	E32Y	Neutral	0.015
USH2A	O75445-1.3	S33A	Neutral	0.112
USH2A	O75445-1.3	S33C	Neutral	0.424
USH2A	O75445-1.3	S33D	Neutral	0.192
USH2A	O75445-1.3	S33E	Neutral	0.111
USH2A	O75445-1.3	S33F	Neutral	0.342
USH2A	O75445-1.3	S33G	Neutral	0.119
USH2A	O75445-1.3	S33H	Neutral	0.147
USH2A	O75445-1.3	S33I	Neutral	0.427
USH2A	O75445-1.3	S33K	Neutral	0.061
USH2A	O75445-1.3	S33L	Neutral	0.415
USH2A	O75445-1.3	S33M	Neutral	0.197
USH2A	O75445-1.3	S33N	Neutral	0.076
USH2A	O75445-1.3	S33P	Neutral	0.362
USH2A	O75445-1.3	S33Q	Neutral	0.08
USH2A	O75445-1.3	S33R	Neutral	0.089
USH2A	O75445-1.3	S33T	Neutral	0.073
USH2A	O75445-1.3	S33V	Pathogenic	0.506
USH2A	O75445-1.3	S33W	Neutral	0.378
USH2A	O75445-1.3	S33Y	Neutral	0.221
USH2A	O75445-1.3	R34A	Neutral	0.07
USH2A	O75445-1.3	R34C	Pathogenic	0.504
USH2A	O75445-1.3	R34D	Neutral	0.18
USH2A	O75445-1.3	R34E	Neutral	0.074
USH2A	O75445-1.3	R34F	Pathogenic	0.88
USH2A	O75445-1.3	R34G	Neutral	0.075
USH2A	O75445-1.3	R34H	Neutral	0.135
USH2A	O75445-1.3	R34I	Pathogenic	0.838
USH2A	O75445-1.3	R34K	Neutral	0.029
USH2A	O75445-1.3	R34L	Pathogenic	0.683
USH2A	O75445-1.3	R34M	Neutral	0.428
USH2A	O75445-1.3	R34N	Neutral	0.051
USH2A	O75445-1.3	R34P	Neutral	0.307
USH2A	O75445-1.3	R34Q	Neutral	0.048
USH2A	O75445-1.3	R34S	Neutral	0.072
USH2A	O75445-1.3	R34T	Neutral	0.145
USH2A	O75445-1.3	R34V	Pathogenic	0.678
USH2A	O75445-1.3	R34W	Pathogenic	0.896
USH2A	O75445-1.3	R34Y	Pathogenic	0.72
USH2A	O75445-1.3	G35A	Pathogenic	0.878
USH2A	O75445-1.3	G35C	Pathogenic	0.985
USH2A	O75445-1.3	G35D	Pathogenic	0.906
USH2A	O75445-1.3	G35E	Pathogenic	0.92
USH2A	O75445-1.3	G35F	Pathogenic	0.953
USH2A	O75445-1.3	G35H	Pathogenic	0.87
USH2A	O75445-1.3	G35I	Pathogenic	0.985
USH2A	O75445-1.3	G35K	Pathogenic	0.856
USH2A	O75445-1.3	G35L	Pathogenic	0.984
USH2A	O75445-1.3	G35M	Pathogenic	0.956
USH2A	O75445-1.3	G35N	Pathogenic	0.767
USH2A	O75445-1.3	G35P	Pathogenic	0.957
USH2A	O75445-1.3	G35Q	Pathogenic	0.888
USH2A	O75445-1.3	G35R	Pathogenic	0.798
USH2A	O75445-1.3	G35S	Pathogenic	0.839
USH2A	O75445-1.3	G35T	Pathogenic	0.941
USH2A	O75445-1.3	G35V	Pathogenic	0.976
USH2A	O75445-1.3	G35W	Pathogenic	0.819
USH2A	O75445-1.3	G35Y	Pathogenic	0.917
USH2A	O75445-1.3	L36A	Neutral	0.073
USH2A	O75445-1.3	L36C	Neutral	0.094
USH2A	O75445-1.3	L36D	Pathogenic	0.776
USH2A	O75445-1.3	L36E	Pathogenic	0.717
USH2A	O75445-1.3	L36F	Neutral	0.073
USH2A	O75445-1.3	L36G	Neutral	0.372
USH2A	O75445-1.3	L36H	Pathogenic	0.697
USH2A	O75445-1.3	L36I	Neutral	0.021
USH2A	O75445-1.3	L36K	Pathogenic	0.6
USH2A	O75445-1.3	L36M	Neutral	0.025
USH2A	O75445-1.3	L36N	Pathogenic	0.62
USH2A	O75445-1.3	L36P	Neutral	0.412
USH2A	O75445-1.3	L36Q	Pathogenic	0.514
USH2A	O75445-1.3	L36R	Neutral	0.499
USH2A	O75445-1.3	L36S	Neutral	0.205
USH2A	O75445-1.3	L36T	Neutral	0.157
USH2A	O75445-1.3	L36V	Neutral	0.032
USH2A	O75445-1.3	L36W	Neutral	0.174
USH2A	O75445-1.3	L36Y	Neutral	0.17
USH2A	O75445-1.3	F37A	Pathogenic	0.963
USH2A	O75445-1.3	F37C	Pathogenic	0.971
USH2A	O75445-1.3	F37D	Pathogenic	0.995
USH2A	O75445-1.3	F37E	Pathogenic	0.997
USH2A	O75445-1.3	F37G	Pathogenic	0.974
USH2A	O75445-1.3	F37H	Pathogenic	0.985
USH2A	O75445-1.3	F37I	Pathogenic	0.937
USH2A	O75445-1.3	F37K	Pathogenic	0.999
USH2A	O75445-1.3	F37L	Pathogenic	0.939
USH2A	O75445-1.3	F37M	Pathogenic	0.951
USH2A	O75445-1.3	F37N	Pathogenic	0.996
USH2A	O75445-1.3	F37P	Pathogenic	0.996
USH2A	O75445-1.3	F37Q	Pathogenic	0.997
USH2A	O75445-1.3	F37R	Pathogenic	0.998
USH2A	O75445-1.3	F37S	Pathogenic	0.974
USH2A	O75445-1.3	F37T	Pathogenic	0.984
USH2A	O75445-1.3	F37V	Pathogenic	0.961
USH2A	O75445-1.3	F37W	Pathogenic	0.825
USH2A	O75445-1.3	F37Y	Pathogenic	0.688
USH2A	O75445-1.3	P38A	Pathogenic	0.926
USH2A	O75445-1.3	P38C	Pathogenic	0.991
USH2A	O75445-1.3	P38D	Pathogenic	0.977
USH2A	O75445-1.3	P38E	Pathogenic	0.958
USH2A	O75445-1.3	P38F	Pathogenic	0.99
USH2A	O75445-1.3	P38G	Pathogenic	0.947
USH2A	O75445-1.3	P38H	Pathogenic	0.964
USH2A	O75445-1.3	P38I	Pathogenic	0.985
USH2A	O75445-1.3	P38K	Pathogenic	0.921
USH2A	O75445-1.3	P38L	Pathogenic	0.984
USH2A	O75445-1.3	P38M	Pathogenic	0.955
USH2A	O75445-1.3	P38N	Pathogenic	0.987
USH2A	O75445-1.3	P38Q	Pathogenic	0.94
USH2A	O75445-1.3	P38R	Pathogenic	0.947
USH2A	O75445-1.3	P38S	Pathogenic	0.947
USH2A	O75445-1.3	P38T	Pathogenic	0.961
USH2A	O75445-1.3	P38V	Pathogenic	0.975
USH2A	O75445-1.3	P38W	Pathogenic	0.981
USH2A	O75445-1.3	P38Y	Pathogenic	0.961
USH2A	O75445-1.3	R39A	Pathogenic	0.582
USH2A	O75445-1.3	R39C	Pathogenic	0.949
USH2A	O75445-1.3	R39D	Pathogenic	0.801
USH2A	O75445-1.3	R39E	Pathogenic	0.595
USH2A	O75445-1.3	R39F	Pathogenic	0.993
USH2A	O75445-1.3	R39G	Pathogenic	0.597
USH2A	O75445-1.3	R39H	Pathogenic	0.742
USH2A	O75445-1.3	R39I	Pathogenic	0.99
USH2A	O75445-1.3	R39K	Neutral	0.353
USH2A	O75445-1.3	R39L	Pathogenic	0.975
USH2A	O75445-1.3	R39M	Pathogenic	0.932
USH2A	O75445-1.3	R39N	Neutral	0.496
USH2A	O75445-1.3	R39P	Pathogenic	0.891
USH2A	O75445-1.3	R39Q	Neutral	0.481
USH2A	O75445-1.3	R39S	Pathogenic	0.587
USH2A	O75445-1.3	R39T	Pathogenic	0.758
USH2A	O75445-1.3	R39V	Pathogenic	0.975
USH2A	O75445-1.3	R39W	Pathogenic	0.994
USH2A	O75445-1.3	R39Y	Pathogenic	0.979
USH2A	O75445-1.3	L40A	Pathogenic	0.591
USH2A	O75445-1.3	L40C	Pathogenic	0.655
USH2A	O75445-1.3	L40D	Pathogenic	0.985
USH2A	O75445-1.3	L40E	Pathogenic	0.979
USH2A	O75445-1.3	L40F	Pathogenic	0.592
USH2A	O75445-1.3	L40G	Pathogenic	0.916
USH2A	O75445-1.3	L40H	Pathogenic	0.977
USH2A	O75445-1.3	L40I	Neutral	0.285
USH2A	O75445-1.3	L40K	Pathogenic	0.965
USH2A	O75445-1.3	L40M	Neutral	0.324
USH2A	O75445-1.3	L40N	Pathogenic	0.968
USH2A	O75445-1.3	L40P	Pathogenic	0.928
USH2A	O75445-1.3	L40Q	Pathogenic	0.951
USH2A	O75445-1.3	L40R	Pathogenic	0.948
USH2A	O75445-1.3	L40S	Pathogenic	0.826
USH2A	O75445-1.3	L40T	Pathogenic	0.774
USH2A	O75445-1.3	L40V	Neutral	0.374
USH2A	O75445-1.3	L40W	Pathogenic	0.795
USH2A	O75445-1.3	L40Y	Pathogenic	0.791
USH2A	O75445-1.3	E41A	Pathogenic	0.762
USH2A	O75445-1.3	E41C	Pathogenic	0.99
USH2A	O75445-1.3	E41D	Neutral	0.28
USH2A	O75445-1.3	E41F	Pathogenic	0.983
USH2A	O75445-1.3	E41G	Pathogenic	0.774
USH2A	O75445-1.3	E41H	Pathogenic	0.788
USH2A	O75445-1.3	E41I	Pathogenic	0.988
USH2A	O75445-1.3	E41K	Neutral	0.434
USH2A	O75445-1.3	E41L	Pathogenic	0.988
USH2A	O75445-1.3	E41M	Pathogenic	0.965
USH2A	O75445-1.3	E41N	Pathogenic	0.694
USH2A	O75445-1.3	E41P	Pathogenic	0.892
USH2A	O75445-1.3	E41Q	Neutral	0.405
USH2A	O75445-1.3	E41R	Pathogenic	0.537
USH2A	O75445-1.3	E41S	Pathogenic	0.59
USH2A	O75445-1.3	E41T	Pathogenic	0.878
USH2A	O75445-1.3	E41V	Pathogenic	0.975
USH2A	O75445-1.3	E41W	Pathogenic	0.968
USH2A	O75445-1.3	E41Y	Pathogenic	0.933
USH2A	O75445-1.3	N42A	Pathogenic	0.98
USH2A	O75445-1.3	N42C	Pathogenic	0.997
USH2A	O75445-1.3	N42D	Pathogenic	0.862
USH2A	O75445-1.3	N42E	Pathogenic	0.911
USH2A	O75445-1.3	N42F	Pathogenic	0.994
USH2A	O75445-1.3	N42G	Pathogenic	0.816
USH2A	O75445-1.3	N42H	Pathogenic	0.827
USH2A	O75445-1.3	N42I	Pathogenic	0.996
USH2A	O75445-1.3	N42K	Pathogenic	0.842
USH2A	O75445-1.3	N42L	Pathogenic	0.996
USH2A	O75445-1.3	N42M	Pathogenic	0.988
USH2A	O75445-1.3	N42P	Pathogenic	0.992
USH2A	O75445-1.3	N42Q	Pathogenic	0.912
USH2A	O75445-1.3	N42R	Pathogenic	0.779
USH2A	O75445-1.3	N42S	Pathogenic	0.81
USH2A	O75445-1.3	N42T	Pathogenic	0.955
USH2A	O75445-1.3	N42V	Pathogenic	0.997
USH2A	O75445-1.3	N42W	Pathogenic	0.995
USH2A	O75445-1.3	N42Y	Pathogenic	0.976
USH2A	O75445-1.3	V43A	Neutral	0.227
USH2A	O75445-1.3	V43C	Neutral	0.469
USH2A	O75445-1.3	V43D	Pathogenic	0.928
USH2A	O75445-1.3	V43E	Pathogenic	0.88
USH2A	O75445-1.3	V43F	Neutral	0.423
USH2A	O75445-1.3	V43G	Pathogenic	0.689
USH2A	O75445-1.3	V43H	Pathogenic	0.895
USH2A	O75445-1.3	V43I	Neutral	0.037
USH2A	O75445-1.3	V43K	Pathogenic	0.791
USH2A	O75445-1.3	V43L	Neutral	0.161
USH2A	O75445-1.3	V43M	Neutral	0.132
USH2A	O75445-1.3	V43N	Pathogenic	0.933
USH2A	O75445-1.3	V43P	Pathogenic	0.723
USH2A	O75445-1.3	V43Q	Pathogenic	0.835
USH2A	O75445-1.3	V43R	Pathogenic	0.851
USH2A	O75445-1.3	V43S	Pathogenic	0.688
USH2A	O75445-1.3	V43T	Neutral	0.41
USH2A	O75445-1.3	V43W	Pathogenic	0.662
USH2A	O75445-1.3	V43Y	Neutral	0.341
USH2A	O75445-1.3	G44A	Pathogenic	0.507
USH2A	O75445-1.3	G44C	Pathogenic	0.903
USH2A	O75445-1.3	G44D	Pathogenic	0.577
USH2A	O75445-1.3	G44E	Pathogenic	0.621
USH2A	O75445-1.3	G44F	Pathogenic	0.742
USH2A	O75445-1.3	G44H	Neutral	0.488
USH2A	O75445-1.3	G44I	Pathogenic	0.904
USH2A	O75445-1.3	G44K	Neutral	0.458
USH2A	O75445-1.3	G44L	Pathogenic	0.899
USH2A	O75445-1.3	G44M	Pathogenic	0.756
USH2A	O75445-1.3	G44N	Neutral	0.319
USH2A	O75445-1.3	G44P	Pathogenic	0.758
USH2A	O75445-1.3	G44Q	Pathogenic	0.531
USH2A	O75445-1.3	G44R	Neutral	0.36
USH2A	O75445-1.3	G44S	Neutral	0.425
USH2A	O75445-1.3	G44T	Pathogenic	0.694
USH2A	O75445-1.3	G44V	Pathogenic	0.85
USH2A	O75445-1.3	G44W	Neutral	0.392
USH2A	O75445-1.3	G44Y	Pathogenic	0.611
USH2A	O75445-1.3	A45C	Pathogenic	0.672
USH2A	O75445-1.3	A45D	Pathogenic	0.917
USH2A	O75445-1.3	A45E	Pathogenic	0.719
USH2A	O75445-1.3	A45F	Pathogenic	0.768
USH2A	O75445-1.3	A45G	Pathogenic	0.631
USH2A	O75445-1.3	A45H	Pathogenic	0.749
USH2A	O75445-1.3	A45I	Pathogenic	0.675
USH2A	O75445-1.3	A45K	Pathogenic	0.569
USH2A	O75445-1.3	A45L	Pathogenic	0.664
USH2A	O75445-1.3	A45M	Pathogenic	0.61
USH2A	O75445-1.3	A45N	Pathogenic	0.897
USH2A	O75445-1.3	A45P	Pathogenic	0.783
USH2A	O75445-1.3	A45Q	Pathogenic	0.639
USH2A	O75445-1.3	A45R	Neutral	0.467
USH2A	O75445-1.3	A45S	Pathogenic	0.536
USH2A	O75445-1.3	A45T	Pathogenic	0.546
USH2A	O75445-1.3	A45V	Pathogenic	0.556
USH2A	O75445-1.3	A45W	Pathogenic	0.794
USH2A	O75445-1.3	A45Y	Pathogenic	0.644
USH2A	O75445-1.3	F46A	Pathogenic	0.795
USH2A	O75445-1.3	F46C	Pathogenic	0.836
USH2A	O75445-1.3	F46D	Pathogenic	0.97
USH2A	O75445-1.3	F46E	Pathogenic	0.982
USH2A	O75445-1.3	F46G	Pathogenic	0.849
USH2A	O75445-1.3	F46H	Pathogenic	0.905
USH2A	O75445-1.3	F46I	Pathogenic	0.691
USH2A	O75445-1.3	F46K	Pathogenic	0.993
USH2A	O75445-1.3	F46L	Pathogenic	0.699
USH2A	O75445-1.3	F46M	Pathogenic	0.746
USH2A	O75445-1.3	F46N	Pathogenic	0.972
USH2A	O75445-1.3	F46P	Pathogenic	0.972
USH2A	O75445-1.3	F46Q	Pathogenic	0.981
USH2A	O75445-1.3	F46R	Pathogenic	0.99
USH2A	O75445-1.3	F46S	Pathogenic	0.848
USH2A	O75445-1.3	F46T	Pathogenic	0.902
USH2A	O75445-1.3	F46V	Pathogenic	0.786
USH2A	O75445-1.3	F46W	Neutral	0.415
USH2A	O75445-1.3	F46Y	Neutral	0.249
USH2A	O75445-1.3	K47A	Pathogenic	0.833
USH2A	O75445-1.3	K47C	Pathogenic	0.985
USH2A	O75445-1.3	K47D	Pathogenic	0.863
USH2A	O75445-1.3	K47E	Pathogenic	0.697
USH2A	O75445-1.3	K47F	Pathogenic	0.998
USH2A	O75445-1.3	K47G	Pathogenic	0.841
USH2A	O75445-1.3	K47H	Pathogenic	0.959
USH2A	O75445-1.3	K47I	Pathogenic	0.997
USH2A	O75445-1.3	K47L	Pathogenic	0.993
USH2A	O75445-1.3	K47M	Pathogenic	0.98
USH2A	O75445-1.3	K47N	Pathogenic	0.779
USH2A	O75445-1.3	K47P	Pathogenic	0.927
USH2A	O75445-1.3	K47Q	Pathogenic	0.769
USH2A	O75445-1.3	K47R	Pathogenic	0.564
USH2A	O75445-1.3	K47S	Pathogenic	0.69
USH2A	O75445-1.3	K47T	Pathogenic	0.918
USH2A	O75445-1.3	K47V	Pathogenic	0.984
USH2A	O75445-1.3	K47W	Pathogenic	0.996
USH2A	O75445-1.3	K47Y	Pathogenic	0.991
USH2A	O75445-1.3	K48A	Neutral	0.018
USH2A	O75445-1.3	K48C	Neutral	0.201
USH2A	O75445-1.3	K48D	Neutral	0.023
USH2A	O75445-1.3	K48E	Neutral	0.009
USH2A	O75445-1.3	K48F	Pathogenic	0.645
USH2A	O75445-1.3	K48G	Neutral	0.02
USH2A	O75445-1.3	K48H	Neutral	0.081
USH2A	O75445-1.3	K48I	Pathogenic	0.562
USH2A	O75445-1.3	K48L	Neutral	0.348
USH2A	O75445-1.3	K48M	Neutral	0.156
USH2A	O75445-1.3	K48N	Neutral	0.013
USH2A	O75445-1.3	K48P	Neutral	0.046
USH2A	O75445-1.3	K48Q	Neutral	0.012
USH2A	O75445-1.3	K48R	Neutral	0.005
USH2A	O75445-1.3	K48S	Neutral	0.008
USH2A	O75445-1.3	K48T	Neutral	0.04
USH2A	O75445-1.3	K48V	Neutral	0.186
USH2A	O75445-1.3	K48W	Neutral	0.481
USH2A	O75445-1.3	K48Y	Neutral	0.303
USH2A	O75445-1.3	V49A	Neutral	0.42
USH2A	O75445-1.3	V49C	Pathogenic	0.685
USH2A	O75445-1.3	V49D	Pathogenic	0.97
USH2A	O75445-1.3	V49E	Pathogenic	0.947
USH2A	O75445-1.3	V49F	Pathogenic	0.644
USH2A	O75445-1.3	V49G	Pathogenic	0.845
USH2A	O75445-1.3	V49H	Pathogenic	0.955
USH2A	O75445-1.3	V49I	Neutral	0.087
USH2A	O75445-1.3	V49K	Pathogenic	0.903
USH2A	O75445-1.3	V49L	Neutral	0.321
USH2A	O75445-1.3	V49M	Neutral	0.272
USH2A	O75445-1.3	V49N	Pathogenic	0.972
USH2A	O75445-1.3	V49P	Pathogenic	0.866
USH2A	O75445-1.3	V49Q	Pathogenic	0.926
USH2A	O75445-1.3	V49R	Pathogenic	0.934
USH2A	O75445-1.3	V49S	Pathogenic	0.844
USH2A	O75445-1.3	V49T	Pathogenic	0.631
USH2A	O75445-1.3	V49W	Pathogenic	0.828
USH2A	O75445-1.3	V49Y	Pathogenic	0.56
USH2A	O75445-1.3	S50A	Pathogenic	0.56
USH2A	O75445-1.3	S50C	Pathogenic	0.881
USH2A	O75445-1.3	S50D	Pathogenic	0.706
USH2A	O75445-1.3	S50E	Pathogenic	0.557
USH2A	O75445-1.3	S50F	Pathogenic	0.84
USH2A	O75445-1.3	S50G	Pathogenic	0.575
USH2A	O75445-1.3	S50H	Pathogenic	0.635
USH2A	O75445-1.3	S50I	Pathogenic	0.882
USH2A	O75445-1.3	S50K	Neutral	0.394
USH2A	O75445-1.3	S50L	Pathogenic	0.877
USH2A	O75445-1.3	S50M	Pathogenic	0.712
USH2A	O75445-1.3	S50N	Neutral	0.451
USH2A	O75445-1.3	S50P	Pathogenic	0.851
USH2A	O75445-1.3	S50Q	Neutral	0.466
USH2A	O75445-1.3	S50R	Neutral	0.496
USH2A	O75445-1.3	S50T	Neutral	0.442
USH2A	O75445-1.3	S50V	Pathogenic	0.912
USH2A	O75445-1.3	S50W	Pathogenic	0.859
USH2A	O75445-1.3	S50Y	Pathogenic	0.741
USH2A	O75445-1.3	I51A	Neutral	0.075
USH2A	O75445-1.3	I51C	Neutral	0.097
USH2A	O75445-1.3	I51D	Pathogenic	0.611
USH2A	O75445-1.3	I51E	Pathogenic	0.724
USH2A	O75445-1.3	I51F	Neutral	0.07
USH2A	O75445-1.3	I51G	Neutral	0.38
USH2A	O75445-1.3	I51H	Pathogenic	0.705
USH2A	O75445-1.3	I51K	Pathogenic	0.78
USH2A	O75445-1.3	I51L	Neutral	0.021
USH2A	O75445-1.3	I51M	Neutral	0.058
USH2A	O75445-1.3	I51N	Pathogenic	0.629
USH2A	O75445-1.3	I51P	Neutral	0.42
USH2A	O75445-1.3	I51Q	Pathogenic	0.714
USH2A	O75445-1.3	I51R	Pathogenic	0.702
USH2A	O75445-1.3	I51S	Neutral	0.211
USH2A	O75445-1.3	I51T	Neutral	0.161
USH2A	O75445-1.3	I51V	Neutral	0.006
USH2A	O75445-1.3	I51W	Neutral	0.31
USH2A	O75445-1.3	I51Y	Neutral	0.175
USH2A	O75445-1.3	V52A	Neutral	0.088
USH2A	O75445-1.3	V52C	Neutral	0.225
USH2A	O75445-1.3	V52D	Pathogenic	0.809
USH2A	O75445-1.3	V52E	Pathogenic	0.706
USH2A	O75445-1.3	V52F	Neutral	0.194
USH2A	O75445-1.3	V52G	Neutral	0.421
USH2A	O75445-1.3	V52H	Pathogenic	0.737
USH2A	O75445-1.3	V52I	Neutral	0.013
USH2A	O75445-1.3	V52K	Pathogenic	0.553
USH2A	O75445-1.3	V52L	Neutral	0.059
USH2A	O75445-1.3	V52M	Neutral	0.047
USH2A	O75445-1.3	V52N	Pathogenic	0.821
USH2A	O75445-1.3	V52P	Neutral	0.462
USH2A	O75445-1.3	V52Q	Pathogenic	0.624
USH2A	O75445-1.3	V52R	Pathogenic	0.652
USH2A	O75445-1.3	V52S	Neutral	0.42
USH2A	O75445-1.3	V52T	Neutral	0.186
USH2A	O75445-1.3	V52W	Neutral	0.391
USH2A	O75445-1.3	V52Y	Neutral	0.145
USH2A	O75445-1.3	P53A	Pathogenic	0.926
USH2A	O75445-1.3	P53C	Pathogenic	0.991
USH2A	O75445-1.3	P53D	Pathogenic	0.977
USH2A	O75445-1.3	P53E	Pathogenic	0.958
USH2A	O75445-1.3	P53F	Pathogenic	0.99
USH2A	O75445-1.3	P53G	Pathogenic	0.947
USH2A	O75445-1.3	P53H	Pathogenic	0.964
USH2A	O75445-1.3	P53I	Pathogenic	0.985
USH2A	O75445-1.3	P53K	Pathogenic	0.921
USH2A	O75445-1.3	P53L	Pathogenic	0.984
USH2A	O75445-1.3	P53M	Pathogenic	0.955
USH2A	O75445-1.3	P53N	Pathogenic	0.987
USH2A	O75445-1.3	P53Q	Pathogenic	0.94
USH2A	O75445-1.3	P53R	Pathogenic	0.947
USH2A	O75445-1.3	P53S	Pathogenic	0.947
USH2A	O75445-1.3	P53T	Pathogenic	0.961
USH2A	O75445-1.3	P53V	Pathogenic	0.975
USH2A	O75445-1.3	P53W	Pathogenic	0.981
USH2A	O75445-1.3	P53Y	Pathogenic	0.961
USH2A	O75445-1.3	T54A	Neutral	0.028
USH2A	O75445-1.3	T54C	Neutral	0.145
USH2A	O75445-1.3	T54D	Neutral	0.187
USH2A	O75445-1.3	T54E	Neutral	0.121
USH2A	O75445-1.3	T54F	Neutral	0.158
USH2A	O75445-1.3	T54G	Neutral	0.083
USH2A	O75445-1.3	T54H	Neutral	0.138
USH2A	O75445-1.3	T54I	Neutral	0.105
USH2A	O75445-1.3	T54K	Neutral	0.066
USH2A	O75445-1.3	T54L	Neutral	0.101
USH2A	O75445-1.3	T54M	Neutral	0.081
USH2A	O75445-1.3	T54N	Neutral	0.083
USH2A	O75445-1.3	T54P	Neutral	0.144
USH2A	O75445-1.3	T54Q	Neutral	0.087
USH2A	O75445-1.3	T54R	Neutral	0.045
USH2A	O75445-1.3	T54S	Neutral	0.017
USH2A	O75445-1.3	T54V	Neutral	0.066
USH2A	O75445-1.3	T54W	Neutral	0.087
USH2A	O75445-1.3	T54Y	Neutral	0.093
USH2A	O75445-1.3	Q55A	Neutral	0.149
USH2A	O75445-1.3	Q55C	Pathogenic	0.702
USH2A	O75445-1.3	Q55D	Neutral	0.144
USH2A	O75445-1.3	Q55E	Neutral	0.051
USH2A	O75445-1.3	Q55F	Pathogenic	0.815
USH2A	O75445-1.3	Q55G	Neutral	0.157
USH2A	O75445-1.3	Q55H	Neutral	0.219
USH2A	O75445-1.3	Q55I	Pathogenic	0.863
USH2A	O75445-1.3	Q55K	Neutral	0.08
USH2A	O75445-1.3	Q55L	Pathogenic	0.724
USH2A	O75445-1.3	Q55M	Neutral	0.285
USH2A	O75445-1.3	Q55N	Neutral	0.154
USH2A	O75445-1.3	Q55P	Neutral	0.311
USH2A	O75445-1.3	Q55R	Neutral	0.055
USH2A	O75445-1.3	Q55S	Neutral	0.073
USH2A	O75445-1.3	Q55T	Neutral	0.283
USH2A	O75445-1.3	Q55V	Pathogenic	0.681
USH2A	O75445-1.3	Q55W	Neutral	0.497
USH2A	O75445-1.3	Q55Y	Neutral	0.316
USH2A	O75445-1.3	A56C	Neutral	0.346
USH2A	O75445-1.3	A56D	Pathogenic	0.742
USH2A	O75445-1.3	A56E	Neutral	0.398
USH2A	O75445-1.3	A56F	Neutral	0.461
USH2A	O75445-1.3	A56G	Neutral	0.306
USH2A	O75445-1.3	A56H	Neutral	0.436
USH2A	O75445-1.3	A56I	Neutral	0.349
USH2A	O75445-1.3	A56K	Neutral	0.255
USH2A	O75445-1.3	A56L	Neutral	0.338
USH2A	O75445-1.3	A56M	Neutral	0.288
USH2A	O75445-1.3	A56N	Pathogenic	0.693
USH2A	O75445-1.3	A56P	Neutral	0.483
USH2A	O75445-1.3	A56Q	Neutral	0.314
USH2A	O75445-1.3	A56R	Neutral	0.185
USH2A	O75445-1.3	A56S	Neutral	0.23
USH2A	O75445-1.3	A56T	Neutral	0.237
USH2A	O75445-1.3	A56V	Neutral	0.244
USH2A	O75445-1.3	A56W	Neutral	0.5
USH2A	O75445-1.3	A56Y	Neutral	0.319
USH2A	O75445-1.3	V57A	Neutral	0.106
USH2A	O75445-1.3	V57C	Neutral	0.263
USH2A	O75445-1.3	V57D	Pathogenic	0.839
USH2A	O75445-1.3	V57E	Pathogenic	0.747
USH2A	O75445-1.3	V57F	Neutral	0.229
USH2A	O75445-1.3	V57G	Neutral	0.473
USH2A	O75445-1.3	V57H	Pathogenic	0.775
USH2A	O75445-1.3	V57I	Neutral	0.015
USH2A	O75445-1.3	V57K	Pathogenic	0.604
USH2A	O75445-1.3	V57L	Neutral	0.072
USH2A	O75445-1.3	V57M	Neutral	0.058
USH2A	O75445-1.3	V57N	Pathogenic	0.85
USH2A	O75445-1.3	V57P	Pathogenic	0.514
USH2A	O75445-1.3	V57Q	Pathogenic	0.672
USH2A	O75445-1.3	V57R	Pathogenic	0.698
USH2A	O75445-1.3	V57S	Neutral	0.472
USH2A	O75445-1.3	V57T	Neutral	0.219
USH2A	O75445-1.3	V57W	Neutral	0.442
USH2A	O75445-1.3	V57Y	Neutral	0.173
USH2A	O75445-1.3	C58A	Pathogenic	0.952
USH2A	O75445-1.3	C58D	Pathogenic	0.998
USH2A	O75445-1.3	C58E	Pathogenic	0.999
USH2A	O75445-1.3	C58F	Pathogenic	0.977
USH2A	O75445-1.3	C58G	Pathogenic	0.993
USH2A	O75445-1.3	C58H	Pathogenic	0.994
USH2A	O75445-1.3	C58I	Pathogenic	0.963
USH2A	O75445-1.3	C58K	Pathogenic	0.994
USH2A	O75445-1.3	C58L	Pathogenic	0.961
USH2A	O75445-1.3	C58M	Pathogenic	0.952
USH2A	O75445-1.3	C58N	Pathogenic	0.998
USH2A	O75445-1.3	C58P	Pathogenic	0.997
USH2A	O75445-1.3	C58Q	Pathogenic	0.996
USH2A	O75445-1.3	C58R	Pathogenic	0.991
USH2A	O75445-1.3	C58S	Pathogenic	0.985
USH2A	O75445-1.3	C58T	Pathogenic	0.985
USH2A	O75445-1.3	C58V	Pathogenic	0.973
USH2A	O75445-1.3	C58W	Pathogenic	0.955
USH2A	O75445-1.3	C58Y	Pathogenic	0.959
USH2A	O75445-1.3	G59A	Pathogenic	0.878
USH2A	O75445-1.3	G59C	Pathogenic	0.985
USH2A	O75445-1.3	G59D	Pathogenic	0.906
USH2A	O75445-1.3	G59E	Pathogenic	0.92
USH2A	O75445-1.3	G59F	Pathogenic	0.953
USH2A	O75445-1.3	G59H	Pathogenic	0.87
USH2A	O75445-1.3	G59I	Pathogenic	0.985
USH2A	O75445-1.3	G59K	Pathogenic	0.856
USH2A	O75445-1.3	G59L	Pathogenic	0.984
USH2A	O75445-1.3	G59M	Pathogenic	0.956
USH2A	O75445-1.3	G59N	Pathogenic	0.767
USH2A	O75445-1.3	G59P	Pathogenic	0.957
USH2A	O75445-1.3	G59Q	Pathogenic	0.888
USH2A	O75445-1.3	G59R	Pathogenic	0.798
USH2A	O75445-1.3	G59S	Pathogenic	0.839
USH2A	O75445-1.3	G59T	Pathogenic	0.941
USH2A	O75445-1.3	G59V	Pathogenic	0.976
USH2A	O75445-1.3	G59W	Pathogenic	0.819
USH2A	O75445-1.3	G59Y	Pathogenic	0.917
USH2A	O75445-1.3	L60A	Neutral	0.1
USH2A	O75445-1.3	L60C	Neutral	0.128
USH2A	O75445-1.3	L60D	Pathogenic	0.83
USH2A	O75445-1.3	L60E	Pathogenic	0.781
USH2A	O75445-1.3	L60F	Neutral	0.1
USH2A	O75445-1.3	L60G	Neutral	0.456
USH2A	O75445-1.3	L60H	Pathogenic	0.765
USH2A	O75445-1.3	L60I	Neutral	0.03
USH2A	O75445-1.3	L60K	Pathogenic	0.679
USH2A	O75445-1.3	L60M	Neutral	0.035
USH2A	O75445-1.3	L60N	Pathogenic	0.698
USH2A	O75445-1.3	L60P	Neutral	0.497
USH2A	O75445-1.3	L60Q	Pathogenic	0.599
USH2A	O75445-1.3	L60R	Pathogenic	0.584
USH2A	O75445-1.3	L60S	Neutral	0.267
USH2A	O75445-1.3	L60T	Neutral	0.208
USH2A	O75445-1.3	L60V	Neutral	0.044
USH2A	O75445-1.3	L60W	Neutral	0.229
USH2A	O75445-1.3	L60Y	Neutral	0.225
USH2A	O75445-1.3	P61A	Pathogenic	0.626
USH2A	O75445-1.3	P61C	Pathogenic	0.937
USH2A	O75445-1.3	P61D	Pathogenic	0.853
USH2A	O75445-1.3	P61E	Pathogenic	0.753
USH2A	O75445-1.3	P61F	Pathogenic	0.932
USH2A	O75445-1.3	P61G	Pathogenic	0.708
USH2A	O75445-1.3	P61H	Pathogenic	0.781
USH2A	O75445-1.3	P61I	Pathogenic	0.896
USH2A	O75445-1.3	P61K	Pathogenic	0.612
USH2A	O75445-1.3	P61L	Pathogenic	0.891
USH2A	O75445-1.3	P61M	Pathogenic	0.739
USH2A	O75445-1.3	P61N	Pathogenic	0.912
USH2A	O75445-1.3	P61Q	Pathogenic	0.679
USH2A	O75445-1.3	P61R	Pathogenic	0.705
USH2A	O75445-1.3	P61S	Pathogenic	0.707
USH2A	O75445-1.3	P61T	Pathogenic	0.766
USH2A	O75445-1.3	P61V	Pathogenic	0.838
USH2A	O75445-1.3	P61W	Pathogenic	0.875
USH2A	O75445-1.3	P61Y	Pathogenic	0.766
USH2A	O75445-1.3	D62A	Neutral	0.179
USH2A	O75445-1.3	D62C	Pathogenic	0.562
USH2A	O75445-1.3	D62E	Neutral	0.006
USH2A	O75445-1.3	D62F	Neutral	0.354
USH2A	O75445-1.3	D62G	Neutral	0.043
USH2A	O75445-1.3	D62H	Neutral	0.074
USH2A	O75445-1.3	D62I	Neutral	0.44
USH2A	O75445-1.3	D62K	Neutral	0.032
USH2A	O75445-1.3	D62L	Pathogenic	0.63
USH2A	O75445-1.3	D62M	Neutral	0.372
USH2A	O75445-1.3	D62N	Neutral	0.021
USH2A	O75445-1.3	D62P	Neutral	0.197
USH2A	O75445-1.3	D62Q	Neutral	0.032
USH2A	O75445-1.3	D62R	Neutral	0.047
USH2A	O75445-1.3	D62S	Neutral	0.041
USH2A	O75445-1.3	D62T	Neutral	0.159
USH2A	O75445-1.3	D62V	Pathogenic	0.519
USH2A	O75445-1.3	D62W	Neutral	0.39
USH2A	O75445-1.3	D62Y	Neutral	0.23
USH2A	O75445-1.3	R63A	Neutral	0.176
USH2A	O75445-1.3	R63C	Pathogenic	0.742
USH2A	O75445-1.3	R63D	Neutral	0.382
USH2A	O75445-1.3	R63E	Neutral	0.184
USH2A	O75445-1.3	R63F	Pathogenic	0.954
USH2A	O75445-1.3	R63G	Neutral	0.186
USH2A	O75445-1.3	R63H	Neutral	0.307
USH2A	O75445-1.3	R63I	Pathogenic	0.936
USH2A	O75445-1.3	R63K	Neutral	0.077
USH2A	O75445-1.3	R63L	Pathogenic	0.859
USH2A	O75445-1.3	R63M	Pathogenic	0.679
USH2A	O75445-1.3	R63N	Neutral	0.132
USH2A	O75445-1.3	R63P	Pathogenic	0.557
USH2A	O75445-1.3	R63Q	Neutral	0.125
USH2A	O75445-1.3	R63S	Neutral	0.18
USH2A	O75445-1.3	R63T	Neutral	0.325
USH2A	O75445-1.3	R63V	Pathogenic	0.856
USH2A	O75445-1.3	R63W	Pathogenic	0.961
USH2A	O75445-1.3	R63Y	Pathogenic	0.879
USH2A	O75445-1.3	S64A	Neutral	0.237
USH2A	O75445-1.3	S64C	Pathogenic	0.643
USH2A	O75445-1.3	S64D	Neutral	0.369
USH2A	O75445-1.3	S64E	Neutral	0.235
USH2A	O75445-1.3	S64F	Pathogenic	0.56
USH2A	O75445-1.3	S64G	Neutral	0.248
USH2A	O75445-1.3	S64H	Neutral	0.297
USH2A	O75445-1.3	S64I	Pathogenic	0.646
USH2A	O75445-1.3	S64K	Neutral	0.137
USH2A	O75445-1.3	S64L	Pathogenic	0.635
USH2A	O75445-1.3	S64M	Neutral	0.376
USH2A	O75445-1.3	S64N	Neutral	0.167
USH2A	O75445-1.3	S64P	Pathogenic	0.582
USH2A	O75445-1.3	S64Q	Neutral	0.175
USH2A	O75445-1.3	S64R	Neutral	0.194
USH2A	O75445-1.3	S64T	Neutral	0.162
USH2A	O75445-1.3	S64V	Pathogenic	0.716
USH2A	O75445-1.3	S64W	Pathogenic	0.598
USH2A	O75445-1.3	S64Y	Neutral	0.411
USH2A	O75445-1.3	T65A	Neutral	0.033
USH2A	O75445-1.3	T65C	Neutral	0.167
USH2A	O75445-1.3	T65D	Neutral	0.215
USH2A	O75445-1.3	T65E	Neutral	0.141
USH2A	O75445-1.3	T65F	Neutral	0.182
USH2A	O75445-1.3	T65G	Neutral	0.097
USH2A	O75445-1.3	T65H	Neutral	0.16
USH2A	O75445-1.3	T65I	Neutral	0.123
USH2A	O75445-1.3	T65K	Neutral	0.078
USH2A	O75445-1.3	T65L	Neutral	0.117
USH2A	O75445-1.3	T65M	Neutral	0.095
USH2A	O75445-1.3	T65N	Neutral	0.096
USH2A	O75445-1.3	T65P	Neutral	0.167
USH2A	O75445-1.3	T65Q	Neutral	0.102
USH2A	O75445-1.3	T65R	Neutral	0.053
USH2A	O75445-1.3	T65S	Neutral	0.02
USH2A	O75445-1.3	T65V	Neutral	0.078
USH2A	O75445-1.3	T65W	Neutral	0.102
USH2A	O75445-1.3	T65Y	Neutral	0.108
USH2A	O75445-1.3	F66A	Pathogenic	0.745
USH2A	O75445-1.3	F66C	Pathogenic	0.793
USH2A	O75445-1.3	F66D	Pathogenic	0.961
USH2A	O75445-1.3	F66E	Pathogenic	0.976
USH2A	O75445-1.3	F66G	Pathogenic	0.808
USH2A	O75445-1.3	F66H	Pathogenic	0.878
USH2A	O75445-1.3	F66I	Pathogenic	0.627
USH2A	O75445-1.3	F66K	Pathogenic	0.991
USH2A	O75445-1.3	F66L	Pathogenic	0.636
USH2A	O75445-1.3	F66M	Pathogenic	0.688
USH2A	O75445-1.3	F66N	Pathogenic	0.964
USH2A	O75445-1.3	F66P	Pathogenic	0.963
USH2A	O75445-1.3	F66Q	Pathogenic	0.975
USH2A	O75445-1.3	F66R	Pathogenic	0.987
USH2A	O75445-1.3	F66S	Pathogenic	0.807
USH2A	O75445-1.3	F66T	Pathogenic	0.873
USH2A	O75445-1.3	F66V	Pathogenic	0.734
USH2A	O75445-1.3	F66W	Neutral	0.348
USH2A	O75445-1.3	F66Y	Neutral	0.199
USH2A	O75445-1.3	C67A	Pathogenic	0.92
USH2A	O75445-1.3	C67D	Pathogenic	0.997
USH2A	O75445-1.3	C67E	Pathogenic	0.998
USH2A	O75445-1.3	C67F	Pathogenic	0.961
USH2A	O75445-1.3	C67G	Pathogenic	0.989
USH2A	O75445-1.3	C67H	Pathogenic	0.99
USH2A	O75445-1.3	C67I	Pathogenic	0.939
USH2A	O75445-1.3	C67K	Pathogenic	0.99
USH2A	O75445-1.3	C67L	Pathogenic	0.936
USH2A	O75445-1.3	C67M	Pathogenic	0.92
USH2A	O75445-1.3	C67N	Pathogenic	0.997
USH2A	O75445-1.3	C67P	Pathogenic	0.994
USH2A	O75445-1.3	C67Q	Pathogenic	0.993
USH2A	O75445-1.3	C67R	Pathogenic	0.985
USH2A	O75445-1.3	C67S	Pathogenic	0.974
USH2A	O75445-1.3	C67T	Pathogenic	0.975
USH2A	O75445-1.3	C67V	Pathogenic	0.955
USH2A	O75445-1.3	C67W	Pathogenic	0.926
USH2A	O75445-1.3	C67Y	Pathogenic	0.932
USH2A	O75445-1.3	H68A	Neutral	0.245
USH2A	O75445-1.3	H68C	Pathogenic	0.656
USH2A	O75445-1.3	H68D	Neutral	0.306
USH2A	O75445-1.3	H68E	Neutral	0.244
USH2A	O75445-1.3	H68F	Neutral	0.469
USH2A	O75445-1.3	H68G	Neutral	0.147
USH2A	O75445-1.3	H68I	Pathogenic	0.869
USH2A	O75445-1.3	H68K	Neutral	0.404
USH2A	O75445-1.3	H68L	Pathogenic	0.863
USH2A	O75445-1.3	H68M	Pathogenic	0.686
USH2A	O75445-1.3	H68N	Neutral	0.084
USH2A	O75445-1.3	H68P	Neutral	0.455
USH2A	O75445-1.3	H68Q	Neutral	0.235
USH2A	O75445-1.3	H68R	Neutral	0.165
USH2A	O75445-1.3	H68S	Neutral	0.147
USH2A	O75445-1.3	H68T	Neutral	0.422
USH2A	O75445-1.3	H68V	Pathogenic	0.798
USH2A	O75445-1.3	H68W	Pathogenic	0.508
USH2A	O75445-1.3	H68Y	Neutral	0.039
USH2A	O75445-1.3	S69A	Neutral	0.281
USH2A	O75445-1.3	S69C	Pathogenic	0.695
USH2A	O75445-1.3	S69D	Neutral	0.425
USH2A	O75445-1.3	S69E	Neutral	0.279
USH2A	O75445-1.3	S69F	Pathogenic	0.617
USH2A	O75445-1.3	S69G	Neutral	0.294
USH2A	O75445-1.3	S69H	Neutral	0.348
USH2A	O75445-1.3	S69I	Pathogenic	0.698
USH2A	O75445-1.3	S69K	Neutral	0.167
USH2A	O75445-1.3	S69L	Pathogenic	0.687
USH2A	O75445-1.3	S69M	Neutral	0.432
USH2A	O75445-1.3	S69N	Neutral	0.202
USH2A	O75445-1.3	S69P	Pathogenic	0.638
USH2A	O75445-1.3	S69Q	Neutral	0.212
USH2A	O75445-1.3	S69R	Neutral	0.233
USH2A	O75445-1.3	S69T	Neutral	0.196
USH2A	O75445-1.3	S69V	Pathogenic	0.761
USH2A	O75445-1.3	S69W	Pathogenic	0.653
USH2A	O75445-1.3	S69Y	Neutral	0.468
USH2A	O75445-1.3	S70A	Neutral	0.108
USH2A	O75445-1.3	S70C	Neutral	0.413
USH2A	O75445-1.3	S70D	Neutral	0.185
USH2A	O75445-1.3	S70E	Neutral	0.107
USH2A	O75445-1.3	S70F	Neutral	0.332
USH2A	O75445-1.3	S70G	Neutral	0.114
USH2A	O75445-1.3	S70H	Neutral	0.142
USH2A	O75445-1.3	S70I	Neutral	0.416
USH2A	O75445-1.3	S70K	Neutral	0.058
USH2A	O75445-1.3	S70L	Neutral	0.404
USH2A	O75445-1.3	S70M	Neutral	0.19
USH2A	O75445-1.3	S70N	Neutral	0.072
USH2A	O75445-1.3	S70P	Neutral	0.352
USH2A	O75445-1.3	S70Q	Neutral	0.076
USH2A	O75445-1.3	S70R	Neutral	0.086
USH2A	O75445-1.3	S70T	Neutral	0.07
USH2A	O75445-1.3	S70V	Neutral	0.495
USH2A	O75445-1.3	S70W	Neutral	0.367
USH2A	O75445-1.3	S70Y	Neutral	0.214
USH2A	O75445-1.3	A71C	Neutral	0.026
USH2A	O75445-1.3	A71D	Neutral	0.127
USH2A	O75445-1.3	A71E	Neutral	0.032
USH2A	O75445-1.3	A71F	Neutral	0.041
USH2A	O75445-1.3	A71G	Neutral	0.022
USH2A	O75445-1.3	A71H	Neutral	0.038
USH2A	O75445-1.3	A71I	Neutral	0.026
USH2A	O75445-1.3	A71K	Neutral	0.017
USH2A	O75445-1.3	A71L	Neutral	0.025
USH2A	O75445-1.3	A71M	Neutral	0.02
USH2A	O75445-1.3	A71N	Neutral	0.102
USH2A	O75445-1.3	A71P	Neutral	0.045
USH2A	O75445-1.3	A71Q	Neutral	0.023
USH2A	O75445-1.3	A71R	Neutral	0.011
USH2A	O75445-1.3	A71S	Neutral	0.015
USH2A	O75445-1.3	A71T	Neutral	0.015
USH2A	O75445-1.3	A71V	Neutral	0.016
USH2A	O75445-1.3	A71W	Neutral	0.048
USH2A	O75445-1.3	A71Y	Neutral	0.023
USH2A	O75445-1.3	A72C	Neutral	0.046
USH2A	O75445-1.3	A72D	Neutral	0.208
USH2A	O75445-1.3	A72E	Neutral	0.057
USH2A	O75445-1.3	A72F	Neutral	0.072
USH2A	O75445-1.3	A72G	Neutral	0.039
USH2A	O75445-1.3	A72H	Neutral	0.066
USH2A	O75445-1.3	A72I	Neutral	0.047
USH2A	O75445-1.3	A72K	Neutral	0.03
USH2A	O75445-1.3	A72L	Neutral	0.044
USH2A	O75445-1.3	A72M	Neutral	0.036
USH2A	O75445-1.3	A72N	Neutral	0.17
USH2A	O75445-1.3	A72P	Neutral	0.078
USH2A	O75445-1.3	A72Q	Neutral	0.04
USH2A	O75445-1.3	A72R	Neutral	0.02
USH2A	O75445-1.3	A72S	Neutral	0.027
USH2A	O75445-1.3	A72T	Neutral	0.028
USH2A	O75445-1.3	A72V	Neutral	0.029
USH2A	O75445-1.3	A72W	Neutral	0.084
USH2A	O75445-1.3	A72Y	Neutral	0.041
USH2A	O75445-1.3	A73C	Neutral	0.02
USH2A	O75445-1.3	A73D	Neutral	0.1
USH2A	O75445-1.3	A73E	Neutral	0.025
USH2A	O75445-1.3	A73F	Neutral	0.032
USH2A	O75445-1.3	A73G	Neutral	0.017
USH2A	O75445-1.3	A73H	Neutral	0.029
USH2A	O75445-1.3	A73I	Neutral	0.02
USH2A	O75445-1.3	A73K	Neutral	0.013
USH2A	O75445-1.3	A73L	Neutral	0.019
USH2A	O75445-1.3	A73M	Neutral	0.015
USH2A	O75445-1.3	A73N	Neutral	0.08
USH2A	O75445-1.3	A73P	Neutral	0.035
USH2A	O75445-1.3	A73Q	Neutral	0.017
USH2A	O75445-1.3	A73R	Neutral	0.009
USH2A	O75445-1.3	A73S	Neutral	0.011
USH2A	O75445-1.3	A73T	Neutral	0.012
USH2A	O75445-1.3	A73V	Neutral	0.012
USH2A	O75445-1.3	A73W	Neutral	0.037
USH2A	O75445-1.3	A73Y	Neutral	0.018
USH2A	O75445-1.3	E74A	Neutral	0.099
USH2A	O75445-1.3	E74C	Pathogenic	0.771
USH2A	O75445-1.3	E74D	Neutral	0.013
USH2A	O75445-1.3	E74F	Pathogenic	0.667
USH2A	O75445-1.3	E74G	Neutral	0.105
USH2A	O75445-1.3	E74H	Neutral	0.113
USH2A	O75445-1.3	E74I	Pathogenic	0.741
USH2A	O75445-1.3	E74K	Neutral	0.026
USH2A	O75445-1.3	E74L	Pathogenic	0.732
USH2A	O75445-1.3	E74M	Neutral	0.486
USH2A	O75445-1.3	E74N	Neutral	0.072
USH2A	O75445-1.3	E74P	Neutral	0.22
USH2A	O75445-1.3	E74Q	Neutral	0.023
USH2A	O75445-1.3	E74R	Neutral	0.038
USH2A	O75445-1.3	E74S	Neutral	0.047
USH2A	O75445-1.3	E74T	Neutral	0.198
USH2A	O75445-1.3	E74V	Pathogenic	0.572
USH2A	O75445-1.3	E74W	Pathogenic	0.506
USH2A	O75445-1.3	E74Y	Neutral	0.324
USH2A	O75445-1.3	S75A	Neutral	0.076
USH2A	O75445-1.3	S75C	Neutral	0.323
USH2A	O75445-1.3	S75D	Neutral	0.134
USH2A	O75445-1.3	S75E	Neutral	0.075
USH2A	O75445-1.3	S75F	Neutral	0.252
USH2A	O75445-1.3	S75G	Neutral	0.08
USH2A	O75445-1.3	S75H	Neutral	0.101
USH2A	O75445-1.3	S75I	Neutral	0.326
USH2A	O75445-1.3	S75K	Neutral	0.04
USH2A	O75445-1.3	S75L	Neutral	0.315
USH2A	O75445-1.3	S75M	Neutral	0.137
USH2A	O75445-1.3	S75N	Neutral	0.05
USH2A	O75445-1.3	S75P	Neutral	0.269
USH2A	O75445-1.3	S75Q	Neutral	0.053
USH2A	O75445-1.3	S75R	Neutral	0.06
USH2A	O75445-1.3	S75T	Neutral	0.048
USH2A	O75445-1.3	S75V	Neutral	0.399
USH2A	O75445-1.3	S75W	Neutral	0.282
USH2A	O75445-1.3	S75Y	Neutral	0.155
USH2A	O75445-1.3	I76A	Neutral	0.099
USH2A	O75445-1.3	I76C	Neutral	0.127
USH2A	O75445-1.3	I76D	Pathogenic	0.679
USH2A	O75445-1.3	I76E	Pathogenic	0.78
USH2A	O75445-1.3	I76F	Neutral	0.092
USH2A	O75445-1.3	I76G	Neutral	0.453
USH2A	O75445-1.3	I76H	Pathogenic	0.763
USH2A	O75445-1.3	I76K	Pathogenic	0.827
USH2A	O75445-1.3	I76L	Neutral	0.028
USH2A	O75445-1.3	I76M	Neutral	0.077
USH2A	O75445-1.3	I76N	Pathogenic	0.696
USH2A	O75445-1.3	I76P	Neutral	0.495
USH2A	O75445-1.3	I76Q	Pathogenic	0.771
USH2A	O75445-1.3	I76R	Pathogenic	0.761
USH2A	O75445-1.3	I76S	Neutral	0.266
USH2A	O75445-1.3	I76T	Neutral	0.207
USH2A	O75445-1.3	I76V	Neutral	0.009
USH2A	O75445-1.3	I76W	Neutral	0.378
USH2A	O75445-1.3	I76Y	Neutral	0.223
USH2A	O75445-1.3	Q77A	Neutral	0.007
USH2A	O75445-1.3	Q77C	Neutral	0.091
USH2A	O75445-1.3	Q77D	Neutral	0.007
USH2A	O75445-1.3	Q77E	Neutral	0.002
USH2A	O75445-1.3	Q77F	Neutral	0.157
USH2A	O75445-1.3	Q77G	Neutral	0.008
USH2A	O75445-1.3	Q77H	Neutral	0.012
USH2A	O75445-1.3	Q77I	Neutral	0.211
USH2A	O75445-1.3	Q77K	Neutral	0.004
USH2A	O75445-1.3	Q77L	Neutral	0.1
USH2A	O75445-1.3	Q77M	Neutral	0.017
USH2A	O75445-1.3	Q77N	Neutral	0.008
USH2A	O75445-1.3	Q77P	Neutral	0.019
USH2A	O75445-1.3	Q77R	Neutral	0.002
USH2A	O75445-1.3	Q77S	Neutral	0.003
USH2A	O75445-1.3	Q77T	Neutral	0.016
USH2A	O75445-1.3	Q77V	Neutral	0.083
USH2A	O75445-1.3	Q77W	Neutral	0.04
USH2A	O75445-1.3	Q77Y	Neutral	0.019
USH2A	O75445-1.3	F78A	Neutral	0.034
USH2A	O75445-1.3	F78C	Neutral	0.044
USH2A	O75445-1.3	F78D	Neutral	0.229
USH2A	O75445-1.3	F78E	Neutral	0.332
USH2A	O75445-1.3	F78G	Neutral	0.048
USH2A	O75445-1.3	F78H	Neutral	0.08
USH2A	O75445-1.3	F78I	Neutral	0.02
USH2A	O75445-1.3	F78K	Pathogenic	0.577
USH2A	O75445-1.3	F78L	Neutral	0.021
USH2A	O75445-1.3	F78M	Neutral	0.026
USH2A	O75445-1.3	F78N	Neutral	0.243
USH2A	O75445-1.3	F78P	Neutral	0.239
USH2A	O75445-1.3	F78Q	Neutral	0.321
USH2A	O75445-1.3	F78R	Neutral	0.475
USH2A	O75445-1.3	F78S	Neutral	0.048
USH2A	O75445-1.3	F78T	Neutral	0.077
USH2A	O75445-1.3	F78V	Neutral	0.032
USH2A	O75445-1.3	F78W	Neutral	0.006
USH2A	O75445-1.3	F78Y	Neutral	0.003
USH2A	O75445-1.3	C79A	Pathogenic	0.955
USH2A	O75445-1.3	C79D	Pathogenic	0.999
USH2A	O75445-1.3	C79E	Pathogenic	0.999
USH2A	O75445-1.3	C79F	Pathogenic	0.978
USH2A	O75445-1.3	C79G	Pathogenic	0.994
USH2A	O75445-1.3	C79H	Pathogenic	0.995
USH2A	O75445-1.3	C79I	Pathogenic	0.966
USH2A	O75445-1.3	C79K	Pathogenic	0.995
USH2A	O75445-1.3	C79L	Pathogenic	0.964
USH2A	O75445-1.3	C79M	Pathogenic	0.955
USH2A	O75445-1.3	C79N	Pathogenic	0.998
USH2A	O75445-1.3	C79P	Pathogenic	0.997
USH2A	O75445-1.3	C79Q	Pathogenic	0.996
USH2A	O75445-1.3	C79R	Pathogenic	0.992
USH2A	O75445-1.3	C79S	Pathogenic	0.986
USH2A	O75445-1.3	C79T	Pathogenic	0.986
USH2A	O75445-1.3	C79V	Pathogenic	0.975
USH2A	O75445-1.3	C79W	Pathogenic	0.958
USH2A	O75445-1.3	C79Y	Pathogenic	0.962
USH2A	O75445-1.3	T80A	Neutral	0.016
USH2A	O75445-1.3	T80C	Neutral	0.086
USH2A	O75445-1.3	T80D	Neutral	0.114
USH2A	O75445-1.3	T80E	Neutral	0.071
USH2A	O75445-1.3	T80F	Neutral	0.095
USH2A	O75445-1.3	T80G	Neutral	0.048
USH2A	O75445-1.3	T80H	Neutral	0.082
USH2A	O75445-1.3	T80I	Neutral	0.062
USH2A	O75445-1.3	T80K	Neutral	0.038
USH2A	O75445-1.3	T80L	Neutral	0.059
USH2A	O75445-1.3	T80M	Neutral	0.047
USH2A	O75445-1.3	T80N	Neutral	0.048
USH2A	O75445-1.3	T80P	Neutral	0.086
USH2A	O75445-1.3	T80Q	Neutral	0.05
USH2A	O75445-1.3	T80R	Neutral	0.026
USH2A	O75445-1.3	T80S	Neutral	0.01
USH2A	O75445-1.3	T80V	Neutral	0.038
USH2A	O75445-1.3	T80W	Neutral	0.051
USH2A	O75445-1.3	T80Y	Neutral	0.054
USH2A	O75445-1.3	Q81A	Pathogenic	0.608
USH2A	O75445-1.3	Q81C	Pathogenic	0.954
USH2A	O75445-1.3	Q81D	Pathogenic	0.598
USH2A	O75445-1.3	Q81E	Neutral	0.323
USH2A	O75445-1.3	Q81F	Pathogenic	0.975
USH2A	O75445-1.3	Q81G	Pathogenic	0.623
USH2A	O75445-1.3	Q81H	Pathogenic	0.713
USH2A	O75445-1.3	Q81I	Pathogenic	0.982
USH2A	O75445-1.3	Q81K	Neutral	0.436
USH2A	O75445-1.3	Q81L	Pathogenic	0.959
USH2A	O75445-1.3	Q81M	Pathogenic	0.779
USH2A	O75445-1.3	Q81N	Pathogenic	0.616
USH2A	O75445-1.3	Q81P	Pathogenic	0.8
USH2A	O75445-1.3	Q81R	Neutral	0.339
USH2A	O75445-1.3	Q81S	Neutral	0.41
USH2A	O75445-1.3	Q81T	Pathogenic	0.777
USH2A	O75445-1.3	Q81V	Pathogenic	0.95
USH2A	O75445-1.3	Q81W	Pathogenic	0.897
USH2A	O75445-1.3	Q81Y	Pathogenic	0.803
USH2A	O75445-1.3	R82A	Neutral	0.153
USH2A	O75445-1.3	R82C	Pathogenic	0.708
USH2A	O75445-1.3	R82D	Neutral	0.343
USH2A	O75445-1.3	R82E	Neutral	0.16
USH2A	O75445-1.3	R82F	Pathogenic	0.946
USH2A	O75445-1.3	R82G	Neutral	0.161
USH2A	O75445-1.3	R82H	Neutral	0.272
USH2A	O75445-1.3	R82I	Pathogenic	0.925
USH2A	O75445-1.3	R82K	Neutral	0.066
USH2A	O75445-1.3	R82L	Pathogenic	0.837
USH2A	O75445-1.3	R82M	Pathogenic	0.641
USH2A	O75445-1.3	R82N	Neutral	0.113
USH2A	O75445-1.3	R82P	Pathogenic	0.514
USH2A	O75445-1.3	R82Q	Neutral	0.108
USH2A	O75445-1.3	R82S	Neutral	0.156
USH2A	O75445-1.3	R82T	Neutral	0.289
USH2A	O75445-1.3	R82V	Pathogenic	0.834
USH2A	O75445-1.3	R82W	Pathogenic	0.954
USH2A	O75445-1.3	R82Y	Pathogenic	0.86
USH2A	O75445-1.3	F83A	Neutral	0.326
USH2A	O75445-1.3	F83C	Neutral	0.389
USH2A	O75445-1.3	F83D	Pathogenic	0.803
USH2A	O75445-1.3	F83E	Pathogenic	0.872
USH2A	O75445-1.3	F83G	Neutral	0.411
USH2A	O75445-1.3	F83H	Pathogenic	0.543
USH2A	O75445-1.3	F83I	Neutral	0.218
USH2A	O75445-1.3	F83K	Pathogenic	0.949
USH2A	O75445-1.3	F83L	Neutral	0.224
USH2A	O75445-1.3	F83M	Neutral	0.268
USH2A	O75445-1.3	F83N	Pathogenic	0.815
USH2A	O75445-1.3	F83P	Pathogenic	0.811
USH2A	O75445-1.3	F83Q	Pathogenic	0.866
USH2A	O75445-1.3	F83R	Pathogenic	0.925
USH2A	O75445-1.3	F83S	Neutral	0.41
USH2A	O75445-1.3	F83T	Pathogenic	0.533
USH2A	O75445-1.3	F83V	Neutral	0.313
USH2A	O75445-1.3	F83W	Neutral	0.081
USH2A	O75445-1.3	F83Y	Neutral	0.04
USH2A	O75445-1.3	C84A	Pathogenic	0.953
USH2A	O75445-1.3	C84D	Pathogenic	0.998
USH2A	O75445-1.3	C84E	Pathogenic	0.999
USH2A	O75445-1.3	C84F	Pathogenic	0.977
USH2A	O75445-1.3	C84G	Pathogenic	0.993
USH2A	O75445-1.3	C84H	Pathogenic	0.994
USH2A	O75445-1.3	C84I	Pathogenic	0.964
USH2A	O75445-1.3	C84K	Pathogenic	0.994
USH2A	O75445-1.3	C84L	Pathogenic	0.962
USH2A	O75445-1.3	C84M	Pathogenic	0.953
USH2A	O75445-1.3	C84N	Pathogenic	0.998
USH2A	O75445-1.3	C84P	Pathogenic	0.997
USH2A	O75445-1.3	C84Q	Pathogenic	0.996
USH2A	O75445-1.3	C84R	Pathogenic	0.991
USH2A	O75445-1.3	C84S	Pathogenic	0.985
USH2A	O75445-1.3	C84T	Pathogenic	0.986
USH2A	O75445-1.3	C84V	Pathogenic	0.974
USH2A	O75445-1.3	C84W	Pathogenic	0.956
USH2A	O75445-1.3	C84Y	Pathogenic	0.96
USH2A	O75445-1.3	I85A	Neutral	0.096
USH2A	O75445-1.3	I85C	Neutral	0.122
USH2A	O75445-1.3	I85D	Pathogenic	0.671
USH2A	O75445-1.3	I85E	Pathogenic	0.773
USH2A	O75445-1.3	I85F	Neutral	0.089
USH2A	O75445-1.3	I85G	Neutral	0.444
USH2A	O75445-1.3	I85H	Pathogenic	0.756
USH2A	O75445-1.3	I85K	Pathogenic	0.822
USH2A	O75445-1.3	I85L	Neutral	0.027
USH2A	O75445-1.3	I85M	Neutral	0.074
USH2A	O75445-1.3	I85N	Pathogenic	0.687
USH2A	O75445-1.3	I85P	Neutral	0.485
USH2A	O75445-1.3	I85Q	Pathogenic	0.764
USH2A	O75445-1.3	I85R	Pathogenic	0.753
USH2A	O75445-1.3	I85S	Neutral	0.258
USH2A	O75445-1.3	I85T	Neutral	0.2
USH2A	O75445-1.3	I85V	Neutral	0.008
USH2A	O75445-1.3	I85W	Neutral	0.369
USH2A	O75445-1.3	I85Y	Neutral	0.217
USH2A	O75445-1.3	Q86A	Pathogenic	0.901
USH2A	O75445-1.3	Q86C	Pathogenic	0.992
USH2A	O75445-1.3	Q86D	Pathogenic	0.897
USH2A	O75445-1.3	Q86E	Pathogenic	0.736
USH2A	O75445-1.3	Q86F	Pathogenic	0.996
USH2A	O75445-1.3	Q86G	Pathogenic	0.906
USH2A	O75445-1.3	Q86H	Pathogenic	0.935
USH2A	O75445-1.3	Q86I	Pathogenic	0.997
USH2A	O75445-1.3	Q86K	Pathogenic	0.819
USH2A	O75445-1.3	Q86L	Pathogenic	0.993
USH2A	O75445-1.3	Q86M	Pathogenic	0.954
USH2A	O75445-1.3	Q86N	Pathogenic	0.904
USH2A	O75445-1.3	Q86P	Pathogenic	0.959
USH2A	O75445-1.3	Q86R	Pathogenic	0.75
USH2A	O75445-1.3	Q86S	Pathogenic	0.802
USH2A	O75445-1.3	Q86T	Pathogenic	0.953
USH2A	O75445-1.3	Q86V	Pathogenic	0.991
USH2A	O75445-1.3	Q86W	Pathogenic	0.981
USH2A	O75445-1.3	Q86Y	Pathogenic	0.96
USH2A	O75445-1.3	D87A	Pathogenic	0.668
USH2A	O75445-1.3	D87C	Pathogenic	0.922
USH2A	O75445-1.3	D87E	Neutral	0.053
USH2A	O75445-1.3	D87F	Pathogenic	0.834
USH2A	O75445-1.3	D87G	Neutral	0.291
USH2A	O75445-1.3	D87H	Neutral	0.423
USH2A	O75445-1.3	D87I	Pathogenic	0.878
USH2A	O75445-1.3	D87K	Neutral	0.232
USH2A	O75445-1.3	D87L	Pathogenic	0.94
USH2A	O75445-1.3	D87M	Pathogenic	0.845
USH2A	O75445-1.3	D87N	Neutral	0.165
USH2A	O75445-1.3	D87P	Pathogenic	0.693
USH2A	O75445-1.3	D87Q	Neutral	0.234
USH2A	O75445-1.3	D87R	Neutral	0.314
USH2A	O75445-1.3	D87S	Neutral	0.283
USH2A	O75445-1.3	D87T	Pathogenic	0.635
USH2A	O75445-1.3	D87V	Pathogenic	0.909
USH2A	O75445-1.3	D87W	Pathogenic	0.855
USH2A	O75445-1.3	D87Y	Pathogenic	0.734
USH2A	O75445-1.3	C88A	Pathogenic	0.947
USH2A	O75445-1.3	C88D	Pathogenic	0.998
USH2A	O75445-1.3	C88E	Pathogenic	0.999
USH2A	O75445-1.3	C88F	Pathogenic	0.974
USH2A	O75445-1.3	C88G	Pathogenic	0.993
USH2A	O75445-1.3	C88H	Pathogenic	0.993
USH2A	O75445-1.3	C88I	Pathogenic	0.96
USH2A	O75445-1.3	C88K	Pathogenic	0.994
USH2A	O75445-1.3	C88L	Pathogenic	0.958
USH2A	O75445-1.3	C88M	Pathogenic	0.947
USH2A	O75445-1.3	C88N	Pathogenic	0.998
USH2A	O75445-1.3	C88P	Pathogenic	0.996
USH2A	O75445-1.3	C88Q	Pathogenic	0.995
USH2A	O75445-1.3	C88R	Pathogenic	0.99
USH2A	O75445-1.3	C88S	Pathogenic	0.983
USH2A	O75445-1.3	C88T	Pathogenic	0.984
USH2A	O75445-1.3	C88V	Pathogenic	0.97
USH2A	O75445-1.3	C88W	Pathogenic	0.951
USH2A	O75445-1.3	C88Y	Pathogenic	0.955
USH2A	O75445-1.3	P89A	Pathogenic	0.89
USH2A	O75445-1.3	P89C	Pathogenic	0.986
USH2A	O75445-1.3	P89D	Pathogenic	0.965
USH2A	O75445-1.3	P89E	Pathogenic	0.936
USH2A	O75445-1.3	P89F	Pathogenic	0.985
USH2A	O75445-1.3	P89G	Pathogenic	0.921
USH2A	O75445-1.3	P89H	Pathogenic	0.945
USH2A	O75445-1.3	P89I	Pathogenic	0.976
USH2A	O75445-1.3	P89K	Pathogenic	0.884
USH2A	O75445-1.3	P89L	Pathogenic	0.975
USH2A	O75445-1.3	P89M	Pathogenic	0.932
USH2A	O75445-1.3	P89N	Pathogenic	0.98
USH2A	O75445-1.3	P89Q	Pathogenic	0.91
USH2A	O75445-1.3	P89R	Pathogenic	0.92
USH2A	O75445-1.3	P89S	Pathogenic	0.921
USH2A	O75445-1.3	P89T	Pathogenic	0.94
USH2A	O75445-1.3	P89V	Pathogenic	0.961
USH2A	O75445-1.3	P89W	Pathogenic	0.971
USH2A	O75445-1.3	P89Y	Pathogenic	0.94
USH2A	O75445-1.3	Y90A	Neutral	0.319
USH2A	O75445-1.3	Y90C	Neutral	0.387
USH2A	O75445-1.3	Y90D	Pathogenic	0.798
USH2A	O75445-1.3	Y90E	Pathogenic	0.743
USH2A	O75445-1.3	Y90F	Neutral	0.068
USH2A	O75445-1.3	Y90G	Neutral	0.404
USH2A	O75445-1.3	Y90H	Neutral	0.088
USH2A	O75445-1.3	Y90I	Pathogenic	0.584
USH2A	O75445-1.3	Y90K	Pathogenic	0.888
USH2A	O75445-1.3	Y90L	Pathogenic	0.572
USH2A	O75445-1.3	Y90M	Pathogenic	0.514
USH2A	O75445-1.3	Y90N	Pathogenic	0.651
USH2A	O75445-1.3	Y90P	Pathogenic	0.646
USH2A	O75445-1.3	Y90Q	Pathogenic	0.547
USH2A	O75445-1.3	Y90R	Pathogenic	0.885
USH2A	O75445-1.3	Y90S	Neutral	0.403
USH2A	O75445-1.3	Y90T	Pathogenic	0.525
USH2A	O75445-1.3	Y90V	Neutral	0.363
USH2A	O75445-1.3	Y90W	Neutral	0.112
USH2A	O75445-1.3	R91A	Pathogenic	0.853
USH2A	O75445-1.3	R91C	Pathogenic	0.987
USH2A	O75445-1.3	R91D	Pathogenic	0.944
USH2A	O75445-1.3	R91E	Pathogenic	0.86
USH2A	O75445-1.3	R91F	Pathogenic	0.998
USH2A	O75445-1.3	R91G	Pathogenic	0.861
USH2A	O75445-1.3	R91H	Pathogenic	0.923
USH2A	O75445-1.3	R91I	Pathogenic	0.997
USH2A	O75445-1.3	R91K	Pathogenic	0.694
USH2A	O75445-1.3	R91L	Pathogenic	0.994
USH2A	O75445-1.3	R91M	Pathogenic	0.983
USH2A	O75445-1.3	R91N	Pathogenic	0.804
USH2A	O75445-1.3	R91P	Pathogenic	0.971
USH2A	O75445-1.3	R91Q	Pathogenic	0.795
USH2A	O75445-1.3	R91S	Pathogenic	0.856
USH2A	O75445-1.3	R91T	Pathogenic	0.929
USH2A	O75445-1.3	R91V	Pathogenic	0.994
USH2A	O75445-1.3	R91W	Pathogenic	0.998
USH2A	O75445-1.3	R91Y	Pathogenic	0.995
USH2A	O75445-1.3	S92A	Neutral	0.392
USH2A	O75445-1.3	S92C	Pathogenic	0.79
USH2A	O75445-1.3	S92D	Pathogenic	0.549
USH2A	O75445-1.3	S92E	Neutral	0.39
USH2A	O75445-1.3	S92F	Pathogenic	0.726
USH2A	O75445-1.3	S92G	Neutral	0.407
USH2A	O75445-1.3	S92H	Neutral	0.469
USH2A	O75445-1.3	S92I	Pathogenic	0.792
USH2A	O75445-1.3	S92K	Neutral	0.248
USH2A	O75445-1.3	S92L	Pathogenic	0.784
USH2A	O75445-1.3	S92M	Pathogenic	0.557
USH2A	O75445-1.3	S92N	Neutral	0.294
USH2A	O75445-1.3	S92P	Pathogenic	0.744
USH2A	O75445-1.3	S92Q	Neutral	0.307
USH2A	O75445-1.3	S92R	Neutral	0.333
USH2A	O75445-1.3	S92T	Neutral	0.286
USH2A	O75445-1.3	S92V	Pathogenic	0.84
USH2A	O75445-1.3	S92W	Pathogenic	0.756
USH2A	O75445-1.3	S92Y	Pathogenic	0.592
USH2A	O75445-1.3	S93A	Neutral	0.285
USH2A	O75445-1.3	S93C	Pathogenic	0.698
USH2A	O75445-1.3	S93D	Neutral	0.428
USH2A	O75445-1.3	S93E	Neutral	0.282
USH2A	O75445-1.3	S93F	Pathogenic	0.621
USH2A	O75445-1.3	S93G	Neutral	0.297
USH2A	O75445-1.3	S93H	Neutral	0.352
USH2A	O75445-1.3	S93I	Pathogenic	0.701
USH2A	O75445-1.3	S93K	Neutral	0.169
USH2A	O75445-1.3	S93L	Pathogenic	0.69
USH2A	O75445-1.3	S93M	Neutral	0.436
USH2A	O75445-1.3	S93N	Neutral	0.204
USH2A	O75445-1.3	S93P	Pathogenic	0.641
USH2A	O75445-1.3	S93Q	Neutral	0.214
USH2A	O75445-1.3	S93R	Neutral	0.236
USH2A	O75445-1.3	S93T	Neutral	0.198
USH2A	O75445-1.3	S93V	Pathogenic	0.763
USH2A	O75445-1.3	S93W	Pathogenic	0.657
USH2A	O75445-1.3	S93Y	Neutral	0.472
USH2A	O75445-1.3	H94A	Neutral	0.029
USH2A	O75445-1.3	H94C	Neutral	0.151
USH2A	O75445-1.3	H94D	Neutral	0.039
USH2A	O75445-1.3	H94E	Neutral	0.029
USH2A	O75445-1.3	H94F	Neutral	0.076
USH2A	O75445-1.3	H94G	Neutral	0.016
USH2A	O75445-1.3	H94I	Neutral	0.381
USH2A	O75445-1.3	H94K	Neutral	0.059
USH2A	O75445-1.3	H94L	Neutral	0.369
USH2A	O75445-1.3	H94M	Neutral	0.169
USH2A	O75445-1.3	H94N	Neutral	0.008
USH2A	O75445-1.3	H94P	Neutral	0.072
USH2A	O75445-1.3	H94Q	Neutral	0.028
USH2A	O75445-1.3	H94R	Neutral	0.018
USH2A	O75445-1.3	H94S	Neutral	0.016
USH2A	O75445-1.3	H94T	Neutral	0.064
USH2A	O75445-1.3	H94V	Neutral	0.269
USH2A	O75445-1.3	H94W	Neutral	0.088
USH2A	O75445-1.3	H94Y	Neutral	0.004
USH2A	O75445-1.3	P95A	Pathogenic	0.564
USH2A	O75445-1.3	P95C	Pathogenic	0.92
USH2A	O75445-1.3	P95D	Pathogenic	0.818
USH2A	O75445-1.3	P95E	Pathogenic	0.702
USH2A	O75445-1.3	P95F	Pathogenic	0.913
USH2A	O75445-1.3	P95G	Pathogenic	0.652
USH2A	O75445-1.3	P95H	Pathogenic	0.733
USH2A	O75445-1.3	P95I	Pathogenic	0.869
USH2A	O75445-1.3	P95K	Pathogenic	0.549
USH2A	O75445-1.3	P95L	Pathogenic	0.863
USH2A	O75445-1.3	P95M	Pathogenic	0.686
USH2A	O75445-1.3	P95N	Pathogenic	0.889
USH2A	O75445-1.3	P95Q	Pathogenic	0.62
USH2A	O75445-1.3	P95R	Pathogenic	0.648
USH2A	O75445-1.3	P95S	Pathogenic	0.651
USH2A	O75445-1.3	P95T	Pathogenic	0.716
USH2A	O75445-1.3	P95V	Pathogenic	0.8
USH2A	O75445-1.3	P95W	Pathogenic	0.844
USH2A	O75445-1.3	P95Y	Pathogenic	0.716
USH2A	O75445-1.3	T96A	Neutral	0.004
USH2A	O75445-1.3	T96C	Neutral	0.023
USH2A	O75445-1.3	T96D	Neutral	0.031
USH2A	O75445-1.3	T96E	Neutral	0.019
USH2A	O75445-1.3	T96F	Neutral	0.025
USH2A	O75445-1.3	T96G	Neutral	0.012
USH2A	O75445-1.3	T96H	Neutral	0.022
USH2A	O75445-1.3	T96I	Neutral	0.016
USH2A	O75445-1.3	T96K	Neutral	0.01
USH2A	O75445-1.3	T96L	Neutral	0.015
USH2A	O75445-1.3	T96M	Neutral	0.012
USH2A	O75445-1.3	T96N	Neutral	0.012
USH2A	O75445-1.3	T96P	Neutral	0.023
USH2A	O75445-1.3	T96Q	Neutral	0.013
USH2A	O75445-1.3	T96R	Neutral	0.007
USH2A	O75445-1.3	T96S	Neutral	0.002
USH2A	O75445-1.3	T96V	Neutral	0.01
USH2A	O75445-1.3	T96W	Neutral	0.013
USH2A	O75445-1.3	T96Y	Neutral	0.014
USH2A	O75445-1.3	Y97A	Pathogenic	0.506
USH2A	O75445-1.3	Y97C	Pathogenic	0.58
USH2A	O75445-1.3	Y97D	Pathogenic	0.896
USH2A	O75445-1.3	Y97E	Pathogenic	0.863
USH2A	O75445-1.3	Y97F	Neutral	0.138
USH2A	O75445-1.3	Y97G	Pathogenic	0.597
USH2A	O75445-1.3	Y97H	Neutral	0.175
USH2A	O75445-1.3	Y97I	Pathogenic	0.755
USH2A	O75445-1.3	Y97K	Pathogenic	0.945
USH2A	O75445-1.3	Y97L	Pathogenic	0.745
USH2A	O75445-1.3	Y97M	Pathogenic	0.698
USH2A	O75445-1.3	Y97N	Pathogenic	0.803
USH2A	O75445-1.3	Y97P	Pathogenic	0.8
USH2A	O75445-1.3	Y97Q	Pathogenic	0.725
USH2A	O75445-1.3	Y97R	Pathogenic	0.944
USH2A	O75445-1.3	Y97S	Pathogenic	0.596
USH2A	O75445-1.3	Y97T	Pathogenic	0.708
USH2A	O75445-1.3	Y97V	Pathogenic	0.555
USH2A	O75445-1.3	Y97W	Neutral	0.216
USH2A	O75445-1.3	T98A	Neutral	0.022
USH2A	O75445-1.3	T98C	Neutral	0.115
USH2A	O75445-1.3	T98D	Neutral	0.15
USH2A	O75445-1.3	T98E	Neutral	0.096
USH2A	O75445-1.3	T98F	Neutral	0.126
USH2A	O75445-1.3	T98G	Neutral	0.065
USH2A	O75445-1.3	T98H	Neutral	0.11
USH2A	O75445-1.3	T98I	Neutral	0.083
USH2A	O75445-1.3	T98K	Neutral	0.052
USH2A	O75445-1.3	T98L	Neutral	0.079
USH2A	O75445-1.3	T98M	Neutral	0.064
USH2A	O75445-1.3	T98N	Neutral	0.065
USH2A	O75445-1.3	T98P	Neutral	0.115
USH2A	O75445-1.3	T98Q	Neutral	0.068
USH2A	O75445-1.3	T98R	Neutral	0.035
USH2A	O75445-1.3	T98S	Neutral	0.013
USH2A	O75445-1.3	T98V	Neutral	0.052
USH2A	O75445-1.3	T98W	Neutral	0.069
USH2A	O75445-1.3	T98Y	Neutral	0.073
USH2A	O75445-1.3	A99C	Neutral	0.045
USH2A	O75445-1.3	A99D	Neutral	0.205
USH2A	O75445-1.3	A99E	Neutral	0.056
USH2A	O75445-1.3	A99F	Neutral	0.071
USH2A	O75445-1.3	A99G	Neutral	0.038
USH2A	O75445-1.3	A99H	Neutral	0.065
USH2A	O75445-1.3	A99I	Neutral	0.046
USH2A	O75445-1.3	A99K	Neutral	0.03
USH2A	O75445-1.3	A99L	Neutral	0.044
USH2A	O75445-1.3	A99M	Neutral	0.035
USH2A	O75445-1.3	A99N	Neutral	0.168
USH2A	O75445-1.3	A99P	Neutral	0.077
USH2A	O75445-1.3	A99Q	Neutral	0.04
USH2A	O75445-1.3	A99R	Neutral	0.02
USH2A	O75445-1.3	A99S	Neutral	0.026
USH2A	O75445-1.3	A99T	Neutral	0.027
USH2A	O75445-1.3	A99V	Neutral	0.028
USH2A	O75445-1.3	A99W	Neutral	0.082
USH2A	O75445-1.3	A99Y	Neutral	0.04
USH2A	O75445-1.3	L100A	Pathogenic	0.67
USH2A	O75445-1.3	L100C	Pathogenic	0.728
USH2A	O75445-1.3	L100D	Pathogenic	0.989
USH2A	O75445-1.3	L100E	Pathogenic	0.985
USH2A	O75445-1.3	L100F	Pathogenic	0.671
USH2A	O75445-1.3	L100G	Pathogenic	0.939
USH2A	O75445-1.3	L100H	Pathogenic	0.983
USH2A	O75445-1.3	L100I	Neutral	0.36
USH2A	O75445-1.3	L100K	Pathogenic	0.975
USH2A	O75445-1.3	L100M	Neutral	0.402
USH2A	O75445-1.3	L100N	Pathogenic	0.977
USH2A	O75445-1.3	L100P	Pathogenic	0.948
USH2A	O75445-1.3	L100Q	Pathogenic	0.965
USH2A	O75445-1.3	L100R	Pathogenic	0.963
USH2A	O75445-1.3	L100S	Pathogenic	0.87
USH2A	O75445-1.3	L100T	Pathogenic	0.828
USH2A	O75445-1.3	L100V	Neutral	0.457
USH2A	O75445-1.3	L100W	Pathogenic	0.845
USH2A	O75445-1.3	L100Y	Pathogenic	0.842
USH2A	O75445-1.3	F101A	Pathogenic	0.576
USH2A	O75445-1.3	F101C	Pathogenic	0.642
USH2A	O75445-1.3	F101D	Pathogenic	0.92
USH2A	O75445-1.3	F101E	Pathogenic	0.95
USH2A	O75445-1.3	F101G	Pathogenic	0.663
USH2A	O75445-1.3	F101H	Pathogenic	0.77
USH2A	O75445-1.3	F101I	Neutral	0.44
USH2A	O75445-1.3	F101K	Pathogenic	0.981
USH2A	O75445-1.3	F101L	Neutral	0.449
USH2A	O75445-1.3	F101M	Pathogenic	0.507
USH2A	O75445-1.3	F101N	Pathogenic	0.925
USH2A	O75445-1.3	F101P	Pathogenic	0.924
USH2A	O75445-1.3	F101Q	Pathogenic	0.948
USH2A	O75445-1.3	F101R	Pathogenic	0.972
USH2A	O75445-1.3	F101S	Pathogenic	0.662
USH2A	O75445-1.3	F101T	Pathogenic	0.763
USH2A	O75445-1.3	F101V	Pathogenic	0.562
USH2A	O75445-1.3	F101W	Neutral	0.199
USH2A	O75445-1.3	F101Y	Neutral	0.104
USH2A	O75445-1.3	S102A	Neutral	0.041
USH2A	O75445-1.3	S102C	Neutral	0.198
USH2A	O75445-1.3	S102D	Neutral	0.074
USH2A	O75445-1.3	S102E	Neutral	0.04
USH2A	O75445-1.3	S102F	Neutral	0.149
USH2A	O75445-1.3	S102G	Neutral	0.043
USH2A	O75445-1.3	S102H	Neutral	0.055
USH2A	O75445-1.3	S102I	Neutral	0.2
USH2A	O75445-1.3	S102K	Neutral	0.021
USH2A	O75445-1.3	S102L	Neutral	0.192
USH2A	O75445-1.3	S102M	Neutral	0.076
USH2A	O75445-1.3	S102N	Neutral	0.027
USH2A	O75445-1.3	S102P	Neutral	0.16
USH2A	O75445-1.3	S102Q	Neutral	0.028
USH2A	O75445-1.3	S102R	Neutral	0.032
USH2A	O75445-1.3	S102T	Neutral	0.026
USH2A	O75445-1.3	S102V	Neutral	0.256
USH2A	O75445-1.3	S102W	Neutral	0.169
USH2A	O75445-1.3	S102Y	Neutral	0.087
USH2A	O75445-1.3	A103C	Neutral	0.035
USH2A	O75445-1.3	A103D	Neutral	0.163
USH2A	O75445-1.3	A103E	Neutral	0.043
USH2A	O75445-1.3	A103F	Neutral	0.055
USH2A	O75445-1.3	A103G	Neutral	0.029
USH2A	O75445-1.3	A103H	Neutral	0.05
USH2A	O75445-1.3	A103I	Neutral	0.035
USH2A	O75445-1.3	A103K	Neutral	0.023
USH2A	O75445-1.3	A103L	Neutral	0.033
USH2A	O75445-1.3	A103M	Neutral	0.027
USH2A	O75445-1.3	A103N	Neutral	0.132
USH2A	O75445-1.3	A103P	Neutral	0.059
USH2A	O75445-1.3	A103Q	Neutral	0.03
USH2A	O75445-1.3	A103R	Neutral	0.015
USH2A	O75445-1.3	A103S	Neutral	0.02
USH2A	O75445-1.3	A103T	Neutral	0.021
USH2A	O75445-1.3	A103V	Neutral	0.021
USH2A	O75445-1.3	A103W	Neutral	0.063
USH2A	O75445-1.3	A103Y	Neutral	0.031
USH2A	O75445-1.3	G104A	Neutral	0.315
USH2A	O75445-1.3	G104C	Pathogenic	0.806
USH2A	O75445-1.3	G104D	Neutral	0.38
USH2A	O75445-1.3	G104E	Neutral	0.423
USH2A	O75445-1.3	G104F	Pathogenic	0.563
USH2A	O75445-1.3	G104H	Neutral	0.299
USH2A	O75445-1.3	G104I	Pathogenic	0.808
USH2A	O75445-1.3	G104K	Neutral	0.275
USH2A	O75445-1.3	G104L	Pathogenic	0.8
USH2A	O75445-1.3	G104M	Pathogenic	0.582
USH2A	O75445-1.3	G104N	Neutral	0.173
USH2A	O75445-1.3	G104P	Pathogenic	0.584
USH2A	O75445-1.3	G104Q	Neutral	0.337
USH2A	O75445-1.3	G104R	Neutral	0.201
USH2A	O75445-1.3	G104S	Neutral	0.249
USH2A	O75445-1.3	G104T	Pathogenic	0.504
USH2A	O75445-1.3	G104V	Pathogenic	0.718
USH2A	O75445-1.3	G104W	Neutral	0.224
USH2A	O75445-1.3	G104Y	Neutral	0.413
USH2A	O75445-1.3	L105A	Neutral	0.158
USH2A	O75445-1.3	L105C	Neutral	0.198
USH2A	O75445-1.3	L105D	Pathogenic	0.892
USH2A	O75445-1.3	L105E	Pathogenic	0.857
USH2A	O75445-1.3	L105F	Neutral	0.158
USH2A	O75445-1.3	L105G	Pathogenic	0.585
USH2A	O75445-1.3	L105H	Pathogenic	0.846
USH2A	O75445-1.3	L105I	Neutral	0.049
USH2A	O75445-1.3	L105K	Pathogenic	0.781
USH2A	O75445-1.3	L105M	Neutral	0.058
USH2A	O75445-1.3	L105N	Pathogenic	0.795
USH2A	O75445-1.3	L105P	Pathogenic	0.625
USH2A	O75445-1.3	L105Q	Pathogenic	0.715
USH2A	O75445-1.3	L105R	Pathogenic	0.703
USH2A	O75445-1.3	L105S	Neutral	0.381
USH2A	O75445-1.3	L105T	Neutral	0.307
USH2A	O75445-1.3	L105V	Neutral	0.072
USH2A	O75445-1.3	L105W	Neutral	0.334
USH2A	O75445-1.3	L105Y	Neutral	0.328
USH2A	O75445-1.3	S106A	Neutral	0.011
USH2A	O75445-1.3	S106C	Neutral	0.062
USH2A	O75445-1.3	S106D	Neutral	0.021
USH2A	O75445-1.3	S106E	Neutral	0.011
USH2A	O75445-1.3	S106F	Neutral	0.044
USH2A	O75445-1.3	S106G	Neutral	0.012
USH2A	O75445-1.3	S106H	Neutral	0.015
USH2A	O75445-1.3	S106I	Neutral	0.062
USH2A	O75445-1.3	S106K	Neutral	0.006
USH2A	O75445-1.3	S106L	Neutral	0.059
USH2A	O75445-1.3	S106M	Neutral	0.021
USH2A	O75445-1.3	S106N	Neutral	0.007
USH2A	O75445-1.3	S106P	Neutral	0.048
USH2A	O75445-1.3	S106Q	Neutral	0.008
USH2A	O75445-1.3	S106R	Neutral	0.009
USH2A	O75445-1.3	S106T	Neutral	0.007
USH2A	O75445-1.3	S106V	Neutral	0.084
USH2A	O75445-1.3	S106W	Neutral	0.051
USH2A	O75445-1.3	S106Y	Neutral	0.025
USH2A	O75445-1.3	S107A	Neutral	0.019
USH2A	O75445-1.3	S107C	Neutral	0.1
USH2A	O75445-1.3	S107D	Neutral	0.035
USH2A	O75445-1.3	S107E	Neutral	0.018
USH2A	O75445-1.3	S107F	Neutral	0.073
USH2A	O75445-1.3	S107G	Neutral	0.02
USH2A	O75445-1.3	S107H	Neutral	0.025
USH2A	O75445-1.3	S107I	Neutral	0.101
USH2A	O75445-1.3	S107K	Neutral	0.01
USH2A	O75445-1.3	S107L	Neutral	0.096
USH2A	O75445-1.3	S107M	Neutral	0.036
USH2A	O75445-1.3	S107N	Neutral	0.012
USH2A	O75445-1.3	S107P	Neutral	0.079
USH2A	O75445-1.3	S107Q	Neutral	0.013
USH2A	O75445-1.3	S107R	Neutral	0.015
USH2A	O75445-1.3	S107T	Neutral	0.012
USH2A	O75445-1.3	S107V	Neutral	0.134
USH2A	O75445-1.3	S107W	Neutral	0.084
USH2A	O75445-1.3	S107Y	Neutral	0.041
USH2A	O75445-1.3	C108A	Pathogenic	0.944
USH2A	O75445-1.3	C108D	Pathogenic	0.998
USH2A	O75445-1.3	C108E	Pathogenic	0.998
USH2A	O75445-1.3	C108F	Pathogenic	0.973
USH2A	O75445-1.3	C108G	Pathogenic	0.992
USH2A	O75445-1.3	C108H	Pathogenic	0.993
USH2A	O75445-1.3	C108I	Pathogenic	0.957
USH2A	O75445-1.3	C108K	Pathogenic	0.993
USH2A	O75445-1.3	C108L	Pathogenic	0.955
USH2A	O75445-1.3	C108M	Pathogenic	0.944
USH2A	O75445-1.3	C108N	Pathogenic	0.998
USH2A	O75445-1.3	C108P	Pathogenic	0.996
USH2A	O75445-1.3	C108Q	Pathogenic	0.995
USH2A	O75445-1.3	C108R	Pathogenic	0.99
USH2A	O75445-1.3	C108S	Pathogenic	0.982
USH2A	O75445-1.3	C108T	Pathogenic	0.983
USH2A	O75445-1.3	C108V	Pathogenic	0.969
USH2A	O75445-1.3	C108W	Pathogenic	0.948
USH2A	O75445-1.3	C108Y	Pathogenic	0.952
USH2A	O75445-1.3	I109A	Neutral	0.117
USH2A	O75445-1.3	I109C	Neutral	0.149
USH2A	O75445-1.3	I109D	Pathogenic	0.718
USH2A	O75445-1.3	I109E	Pathogenic	0.81
USH2A	O75445-1.3	I109F	Neutral	0.109
USH2A	O75445-1.3	I109G	Neutral	0.5
USH2A	O75445-1.3	I109H	Pathogenic	0.795
USH2A	O75445-1.3	I109K	Pathogenic	0.852
USH2A	O75445-1.3	I109L	Neutral	0.034
USH2A	O75445-1.3	I109M	Neutral	0.091
USH2A	O75445-1.3	I109N	Pathogenic	0.734
USH2A	O75445-1.3	I109P	Pathogenic	0.541
USH2A	O75445-1.3	I109Q	Pathogenic	0.803
USH2A	O75445-1.3	I109R	Pathogenic	0.793
USH2A	O75445-1.3	I109S	Neutral	0.303
USH2A	O75445-1.3	I109T	Neutral	0.239
USH2A	O75445-1.3	I109V	Neutral	0.01
USH2A	O75445-1.3	I109W	Neutral	0.423
USH2A	O75445-1.3	I109Y	Neutral	0.257
USH2A	O75445-1.3	T110A	Neutral	0.041
USH2A	O75445-1.3	T110C	Neutral	0.199
USH2A	O75445-1.3	T110D	Neutral	0.254
USH2A	O75445-1.3	T110E	Neutral	0.169
USH2A	O75445-1.3	T110F	Neutral	0.216
USH2A	O75445-1.3	T110G	Neutral	0.117
USH2A	O75445-1.3	T110H	Neutral	0.191
USH2A	O75445-1.3	T110I	Neutral	0.148
USH2A	O75445-1.3	T110K	Neutral	0.095
USH2A	O75445-1.3	T110L	Neutral	0.141
USH2A	O75445-1.3	T110M	Neutral	0.115
USH2A	O75445-1.3	T110N	Neutral	0.117
USH2A	O75445-1.3	T110P	Neutral	0.199
USH2A	O75445-1.3	T110Q	Neutral	0.123
USH2A	O75445-1.3	T110R	Neutral	0.065
USH2A	O75445-1.3	T110S	Neutral	0.025
USH2A	O75445-1.3	T110V	Neutral	0.095
USH2A	O75445-1.3	T110W	Neutral	0.124
USH2A	O75445-1.3	T110Y	Neutral	0.131
USH2A	O75445-1.3	P111A	Neutral	0.01
USH2A	O75445-1.3	P111C	Neutral	0.08
USH2A	O75445-1.3	P111D	Neutral	0.033
USH2A	O75445-1.3	P111E	Neutral	0.017
USH2A	O75445-1.3	P111F	Neutral	0.073
USH2A	O75445-1.3	P111G	Neutral	0.014
USH2A	O75445-1.3	P111H	Neutral	0.02
USH2A	O75445-1.3	P111I	Neutral	0.047
USH2A	O75445-1.3	P111K	Neutral	0.009
USH2A	O75445-1.3	P111L	Neutral	0.045
USH2A	O75445-1.3	P111M	Neutral	0.016
USH2A	O75445-1.3	P111N	Neutral	0.057
USH2A	O75445-1.3	P111Q	Neutral	0.012
USH2A	O75445-1.3	P111R	Neutral	0.014
USH2A	O75445-1.3	P111S	Neutral	0.014
USH2A	O75445-1.3	P111T	Neutral	0.019
USH2A	O75445-1.3	P111V	Neutral	0.029
USH2A	O75445-1.3	P111W	Neutral	0.039
USH2A	O75445-1.3	P111Y	Neutral	0.019
USH2A	O75445-1.3	D112A	Pathogenic	0.969
USH2A	O75445-1.3	D112C	Pathogenic	0.995
USH2A	O75445-1.3	D112E	Neutral	0.462
USH2A	O75445-1.3	D112F	Pathogenic	0.987
USH2A	O75445-1.3	D112G	Pathogenic	0.863
USH2A	O75445-1.3	D112H	Pathogenic	0.918
USH2A	O75445-1.3	D112I	Pathogenic	0.991
USH2A	O75445-1.3	D112K	Pathogenic	0.823
USH2A	O75445-1.3	D112L	Pathogenic	0.996
USH2A	O75445-1.3	D112M	Pathogenic	0.988
USH2A	O75445-1.3	D112N	Pathogenic	0.752
USH2A	O75445-1.3	D112P	Pathogenic	0.972
USH2A	O75445-1.3	D112Q	Pathogenic	0.825
USH2A	O75445-1.3	D112R	Pathogenic	0.875
USH2A	O75445-1.3	D112S	Pathogenic	0.858
USH2A	O75445-1.3	D112T	Pathogenic	0.964
USH2A	O75445-1.3	D112V	Pathogenic	0.993
USH2A	O75445-1.3	D112W	Pathogenic	0.989
USH2A	O75445-1.3	D112Y	Pathogenic	0.977
USH2A	O75445-1.3	K113A	Neutral	0.008
USH2A	O75445-1.3	K113C	Neutral	0.099
USH2A	O75445-1.3	K113D	Neutral	0.01
USH2A	O75445-1.3	K113E	Neutral	0.004
USH2A	O75445-1.3	K113F	Neutral	0.441
USH2A	O75445-1.3	K113G	Neutral	0.009
USH2A	O75445-1.3	K113H	Neutral	0.037
USH2A	O75445-1.3	K113I	Neutral	0.358
USH2A	O75445-1.3	K113L	Neutral	0.188
USH2A	O75445-1.3	K113M	Neutral	0.074
USH2A	O75445-1.3	K113N	Neutral	0.006
USH2A	O75445-1.3	K113P	Neutral	0.02
USH2A	O75445-1.3	K113Q	Neutral	0.005
USH2A	O75445-1.3	K113R	Neutral	0.002
USH2A	O75445-1.3	K113S	Neutral	0.004
USH2A	O75445-1.3	K113T	Neutral	0.018
USH2A	O75445-1.3	K113V	Neutral	0.09
USH2A	O75445-1.3	K113W	Neutral	0.287
USH2A	O75445-1.3	K113Y	Neutral	0.159
USH2A	O75445-1.3	N114A	Neutral	0.014
USH2A	O75445-1.3	N114C	Neutral	0.078
USH2A	O75445-1.3	N114D	Neutral	0.002
USH2A	O75445-1.3	N114E	Neutral	0.003
USH2A	O75445-1.3	N114F	Neutral	0.047
USH2A	O75445-1.3	N114G	Neutral	0.001
USH2A	O75445-1.3	N114H	Neutral	0.001
USH2A	O75445-1.3	N114I	Neutral	0.067
USH2A	O75445-1.3	N114K	Neutral	0.002
USH2A	O75445-1.3	N114L	Neutral	0.064
USH2A	O75445-1.3	N114M	Neutral	0.023
USH2A	O75445-1.3	N114P	Neutral	0.036
USH2A	O75445-1.3	N114Q	Neutral	0.003
USH2A	O75445-1.3	N114R	Neutral	0.001
USH2A	O75445-1.3	N114S	Neutral	0.001
USH2A	O75445-1.3	N114T	Neutral	0.006
USH2A	O75445-1.3	N114V	Neutral	0.09
USH2A	O75445-1.3	N114W	Neutral	0.055
USH2A	O75445-1.3	N114Y	Neutral	0.012
USH2A	O75445-1.3	D115A	Pathogenic	0.945
USH2A	O75445-1.3	D115C	Pathogenic	0.99
USH2A	O75445-1.3	D115E	Neutral	0.325
USH2A	O75445-1.3	D115F	Pathogenic	0.977
USH2A	O75445-1.3	D115G	Pathogenic	0.779
USH2A	O75445-1.3	D115H	Pathogenic	0.863
USH2A	O75445-1.3	D115I	Pathogenic	0.984
USH2A	O75445-1.3	D115K	Pathogenic	0.722
USH2A	O75445-1.3	D115L	Pathogenic	0.993
USH2A	O75445-1.3	D115M	Pathogenic	0.979
USH2A	O75445-1.3	D115N	Pathogenic	0.629
USH2A	O75445-1.3	D115P	Pathogenic	0.951
USH2A	O75445-1.3	D115Q	Pathogenic	0.724
USH2A	O75445-1.3	D115R	Pathogenic	0.797
USH2A	O75445-1.3	D115S	Pathogenic	0.772
USH2A	O75445-1.3	D115T	Pathogenic	0.937
USH2A	O75445-1.3	D115V	Pathogenic	0.988
USH2A	O75445-1.3	D115W	Pathogenic	0.981
USH2A	O75445-1.3	D115Y	Pathogenic	0.959
USH2A	O75445-1.3	L116A	Neutral	0.228
USH2A	O75445-1.3	L116C	Neutral	0.28
USH2A	O75445-1.3	L116D	Pathogenic	0.928
USH2A	O75445-1.3	L116E	Pathogenic	0.905
USH2A	O75445-1.3	L116F	Neutral	0.228
USH2A	O75445-1.3	L116G	Pathogenic	0.69
USH2A	O75445-1.3	L116H	Pathogenic	0.896
USH2A	O75445-1.3	L116I	Neutral	0.075
USH2A	O75445-1.3	L116K	Pathogenic	0.849
USH2A	O75445-1.3	L116M	Neutral	0.089
USH2A	O75445-1.3	L116N	Pathogenic	0.86
USH2A	O75445-1.3	L116P	Pathogenic	0.724
USH2A	O75445-1.3	L116Q	Pathogenic	0.799
USH2A	O75445-1.3	L116R	Pathogenic	0.789
USH2A	O75445-1.3	L116S	Neutral	0.492
USH2A	O75445-1.3	L116T	Neutral	0.411
USH2A	O75445-1.3	L116V	Neutral	0.109
USH2A	O75445-1.3	L116W	Neutral	0.441
USH2A	O75445-1.3	L116Y	Neutral	0.435
USH2A	O75445-1.3	H117A	Neutral	0.155
USH2A	O75445-1.3	H117C	Pathogenic	0.518
USH2A	O75445-1.3	H117D	Neutral	0.199
USH2A	O75445-1.3	H117E	Neutral	0.154
USH2A	O75445-1.3	H117F	Neutral	0.333
USH2A	O75445-1.3	H117G	Neutral	0.089
USH2A	O75445-1.3	H117I	Pathogenic	0.788
USH2A	O75445-1.3	H117K	Neutral	0.276
USH2A	O75445-1.3	H117L	Pathogenic	0.78
USH2A	O75445-1.3	H117M	Pathogenic	0.551
USH2A	O75445-1.3	H117N	Neutral	0.049
USH2A	O75445-1.3	H117P	Neutral	0.32
USH2A	O75445-1.3	H117Q	Neutral	0.148
USH2A	O75445-1.3	H117R	Neutral	0.1
USH2A	O75445-1.3	H117S	Neutral	0.088
USH2A	O75445-1.3	H117T	Neutral	0.291
USH2A	O75445-1.3	H117V	Pathogenic	0.69
USH2A	O75445-1.3	H117W	Neutral	0.368
USH2A	O75445-1.3	H117Y	Neutral	0.022
USH2A	O75445-1.3	P118A	Pathogenic	0.772
USH2A	O75445-1.3	P118C	Pathogenic	0.968
USH2A	O75445-1.3	P118D	Pathogenic	0.921
USH2A	O75445-1.3	P118E	Pathogenic	0.86
USH2A	O75445-1.3	P118F	Pathogenic	0.965
USH2A	O75445-1.3	P118G	Pathogenic	0.83
USH2A	O75445-1.3	P118H	Pathogenic	0.878
USH2A	O75445-1.3	P118I	Pathogenic	0.945
USH2A	O75445-1.3	P118K	Pathogenic	0.761
USH2A	O75445-1.3	P118L	Pathogenic	0.943
USH2A	O75445-1.3	P118M	Pathogenic	0.851
USH2A	O75445-1.3	P118N	Pathogenic	0.954
USH2A	O75445-1.3	P118Q	Pathogenic	0.81
USH2A	O75445-1.3	P118R	Pathogenic	0.828
USH2A	O75445-1.3	P118S	Pathogenic	0.83
USH2A	O75445-1.3	P118T	Pathogenic	0.868
USH2A	O75445-1.3	P118V	Pathogenic	0.913
USH2A	O75445-1.3	P118W	Pathogenic	0.934
USH2A	O75445-1.3	P118Y	Pathogenic	0.868
USH2A	O75445-1.3	N119A	Neutral	0.06
USH2A	O75445-1.3	N119C	Neutral	0.273
USH2A	O75445-1.3	N119D	Neutral	0.008
USH2A	O75445-1.3	N119E	Neutral	0.013
USH2A	O75445-1.3	N119F	Neutral	0.181
USH2A	O75445-1.3	N119G	Neutral	0.006
USH2A	O75445-1.3	N119H	Neutral	0.006
USH2A	O75445-1.3	N119I	Neutral	0.24
USH2A	O75445-1.3	N119K	Neutral	0.007
USH2A	O75445-1.3	N119L	Neutral	0.231
USH2A	O75445-1.3	N119M	Neutral	0.094
USH2A	O75445-1.3	N119P	Neutral	0.141
USH2A	O75445-1.3	N119Q	Neutral	0.013
USH2A	O75445-1.3	N119R	Neutral	0.005
USH2A	O75445-1.3	N119S	Neutral	0.005
USH2A	O75445-1.3	N119T	Neutral	0.027
USH2A	O75445-1.3	N119V	Neutral	0.303
USH2A	O75445-1.3	N119W	Neutral	0.205
USH2A	O75445-1.3	N119Y	Neutral	0.05
USH2A	O75445-1.3	A120C	Neutral	0.03
USH2A	O75445-1.3	A120D	Neutral	0.145
USH2A	O75445-1.3	A120E	Neutral	0.038
USH2A	O75445-1.3	A120F	Neutral	0.048
USH2A	O75445-1.3	A120G	Neutral	0.025
USH2A	O75445-1.3	A120H	Neutral	0.044
USH2A	O75445-1.3	A120I	Neutral	0.031
USH2A	O75445-1.3	A120K	Neutral	0.02
USH2A	O75445-1.3	A120L	Neutral	0.029
USH2A	O75445-1.3	A120M	Neutral	0.023
USH2A	O75445-1.3	A120N	Neutral	0.117
USH2A	O75445-1.3	A120P	Neutral	0.052
USH2A	O75445-1.3	A120Q	Neutral	0.026
USH2A	O75445-1.3	A120R	Neutral	0.013
USH2A	O75445-1.3	A120S	Neutral	0.017
USH2A	O75445-1.3	A120T	Neutral	0.018
USH2A	O75445-1.3	A120V	Neutral	0.019
USH2A	O75445-1.3	A120W	Neutral	0.056
USH2A	O75445-1.3	A120Y	Neutral	0.027
USH2A	O75445-1.3	H121A	Neutral	0.012
USH2A	O75445-1.3	H121C	Neutral	0.065
USH2A	O75445-1.3	H121D	Neutral	0.016
USH2A	O75445-1.3	H121E	Neutral	0.012
USH2A	O75445-1.3	H121F	Neutral	0.031
USH2A	O75445-1.3	H121G	Neutral	0.006
USH2A	O75445-1.3	H121I	Neutral	0.193
USH2A	O75445-1.3	H121K	Neutral	0.024
USH2A	O75445-1.3	H121L	Neutral	0.185
USH2A	O75445-1.3	H121M	Neutral	0.073
USH2A	O75445-1.3	H121N	Neutral	0.003
USH2A	O75445-1.3	H121P	Neutral	0.029
USH2A	O75445-1.3	H121Q	Neutral	0.011
USH2A	O75445-1.3	H121R	Neutral	0.007
USH2A	O75445-1.3	H121S	Neutral	0.006
USH2A	O75445-1.3	H121T	Neutral	0.026
USH2A	O75445-1.3	H121V	Neutral	0.125
USH2A	O75445-1.3	H121W	Neutral	0.036
USH2A	O75445-1.3	H121Y	Neutral	0.001
USH2A	O75445-1.3	S122A	Neutral	0.014
USH2A	O75445-1.3	S122C	Neutral	0.077
USH2A	O75445-1.3	S122D	Neutral	0.026
USH2A	O75445-1.3	S122E	Neutral	0.014
USH2A	O75445-1.3	S122F	Neutral	0.056
USH2A	O75445-1.3	S122G	Neutral	0.015
USH2A	O75445-1.3	S122H	Neutral	0.019
USH2A	O75445-1.3	S122I	Neutral	0.078
USH2A	O75445-1.3	S122K	Neutral	0.007
USH2A	O75445-1.3	S122L	Neutral	0.074
USH2A	O75445-1.3	S122M	Neutral	0.027
USH2A	O75445-1.3	S122N	Neutral	0.009
USH2A	O75445-1.3	S122P	Neutral	0.061
USH2A	O75445-1.3	S122Q	Neutral	0.01
USH2A	O75445-1.3	S122R	Neutral	0.011
USH2A	O75445-1.3	S122T	Neutral	0.009
USH2A	O75445-1.3	S122V	Neutral	0.104
USH2A	O75445-1.3	S122W	Neutral	0.065
USH2A	O75445-1.3	S122Y	Neutral	0.031
USH2A	O75445-1.3	N123A	Pathogenic	0.539
USH2A	O75445-1.3	N123C	Pathogenic	0.873
USH2A	O75445-1.3	N123D	Neutral	0.128
USH2A	O75445-1.3	N123E	Neutral	0.196
USH2A	O75445-1.3	N123F	Pathogenic	0.802
USH2A	O75445-1.3	N123G	Neutral	0.095
USH2A	O75445-1.3	N123H	Neutral	0.101
USH2A	O75445-1.3	N123I	Pathogenic	0.853
USH2A	O75445-1.3	N123K	Neutral	0.112
USH2A	O75445-1.3	N123L	Pathogenic	0.846
USH2A	O75445-1.3	N123M	Pathogenic	0.656
USH2A	O75445-1.3	N123P	Pathogenic	0.75
USH2A	O75445-1.3	N123Q	Neutral	0.197
USH2A	O75445-1.3	N123R	Neutral	0.077
USH2A	O75445-1.3	N123S	Neutral	0.091
USH2A	O75445-1.3	N123T	Neutral	0.335
USH2A	O75445-1.3	N123V	Pathogenic	0.889
USH2A	O75445-1.3	N123W	Pathogenic	0.825
USH2A	O75445-1.3	N123Y	Neutral	0.492
USH2A	O75445-1.3	S124A	Neutral	0.087
USH2A	O75445-1.3	S124C	Neutral	0.356
USH2A	O75445-1.3	S124D	Neutral	0.151
USH2A	O75445-1.3	S124E	Neutral	0.086
USH2A	O75445-1.3	S124F	Neutral	0.28
USH2A	O75445-1.3	S124G	Neutral	0.092
USH2A	O75445-1.3	S124H	Neutral	0.115
USH2A	O75445-1.3	S124I	Neutral	0.359
USH2A	O75445-1.3	S124K	Neutral	0.046
USH2A	O75445-1.3	S124L	Neutral	0.347
USH2A	O75445-1.3	S124M	Neutral	0.156
USH2A	O75445-1.3	S124N	Neutral	0.058
USH2A	O75445-1.3	S124P	Neutral	0.299
USH2A	O75445-1.3	S124Q	Neutral	0.061
USH2A	O75445-1.3	S124R	Neutral	0.068
USH2A	O75445-1.3	S124T	Neutral	0.056
USH2A	O75445-1.3	S124V	Neutral	0.435
USH2A	O75445-1.3	S124W	Neutral	0.313
USH2A	O75445-1.3	S124Y	Neutral	0.176
USH2A	O75445-1.3	A125C	Neutral	0.006
USH2A	O75445-1.3	A125D	Neutral	0.032
USH2A	O75445-1.3	A125E	Neutral	0.007
USH2A	O75445-1.3	A125F	Neutral	0.01
USH2A	O75445-1.3	A125G	Neutral	0.005
USH2A	O75445-1.3	A125H	Neutral	0.009
USH2A	O75445-1.3	A125I	Neutral	0.006
USH2A	O75445-1.3	A125K	Neutral	0.004
USH2A	O75445-1.3	A125L	Neutral	0.006
USH2A	O75445-1.3	A125M	Neutral	0.005
USH2A	O75445-1.3	A125N	Neutral	0.025
USH2A	O75445-1.3	A125P	Neutral	0.01
USH2A	O75445-1.3	A125Q	Neutral	0.005
USH2A	O75445-1.3	A125R	Neutral	0.003
USH2A	O75445-1.3	A125S	Neutral	0.003
USH2A	O75445-1.3	A125T	Neutral	0.004
USH2A	O75445-1.3	A125V	Neutral	0.004
USH2A	O75445-1.3	A125W	Neutral	0.011
USH2A	O75445-1.3	A125Y	Neutral	0.005
USH2A	O75445-1.3	S126A	Pathogenic	0.723
USH2A	O75445-1.3	S126C	Pathogenic	0.938
USH2A	O75445-1.3	S126D	Pathogenic	0.831
USH2A	O75445-1.3	S126E	Pathogenic	0.721
USH2A	O75445-1.3	S126F	Pathogenic	0.915
USH2A	O75445-1.3	S126G	Pathogenic	0.735
USH2A	O75445-1.3	S126H	Pathogenic	0.781
USH2A	O75445-1.3	S126I	Pathogenic	0.939
USH2A	O75445-1.3	S126K	Pathogenic	0.572
USH2A	O75445-1.3	S126L	Pathogenic	0.936
USH2A	O75445-1.3	S126M	Pathogenic	0.835
USH2A	O75445-1.3	S126N	Pathogenic	0.628
USH2A	O75445-1.3	S126P	Pathogenic	0.921
USH2A	O75445-1.3	S126Q	Pathogenic	0.641
USH2A	O75445-1.3	S126R	Pathogenic	0.669
USH2A	O75445-1.3	S126T	Pathogenic	0.619
USH2A	O75445-1.3	S126V	Pathogenic	0.955
USH2A	O75445-1.3	S126W	Pathogenic	0.926
USH2A	O75445-1.3	S126Y	Pathogenic	0.854
USH2A	O75445-1.3	F127A	Pathogenic	0.649
USH2A	O75445-1.3	F127C	Pathogenic	0.709
USH2A	O75445-1.3	F127D	Pathogenic	0.94
USH2A	O75445-1.3	F127E	Pathogenic	0.963
USH2A	O75445-1.3	F127G	Pathogenic	0.728
USH2A	O75445-1.3	F127H	Pathogenic	0.82
USH2A	O75445-1.3	F127I	Pathogenic	0.516
USH2A	O75445-1.3	F127K	Pathogenic	0.986
USH2A	O75445-1.3	F127L	Pathogenic	0.526
USH2A	O75445-1.3	F127M	Pathogenic	0.583
USH2A	O75445-1.3	F127N	Pathogenic	0.944
USH2A	O75445-1.3	F127P	Pathogenic	0.943
USH2A	O75445-1.3	F127Q	Pathogenic	0.961
USH2A	O75445-1.3	F127R	Pathogenic	0.979
USH2A	O75445-1.3	F127S	Pathogenic	0.727
USH2A	O75445-1.3	F127T	Pathogenic	0.814
USH2A	O75445-1.3	F127V	Pathogenic	0.636
USH2A	O75445-1.3	F127W	Neutral	0.253
USH2A	O75445-1.3	F127Y	Neutral	0.136
USH2A	O75445-1.3	I128A	Neutral	0.215
USH2A	O75445-1.3	I128C	Neutral	0.266
USH2A	O75445-1.3	I128D	Pathogenic	0.841
USH2A	O75445-1.3	I128E	Pathogenic	0.898
USH2A	O75445-1.3	I128F	Neutral	0.202
USH2A	O75445-1.3	I128G	Pathogenic	0.674
USH2A	O75445-1.3	I128H	Pathogenic	0.889
USH2A	O75445-1.3	I128K	Pathogenic	0.923
USH2A	O75445-1.3	I128L	Neutral	0.067
USH2A	O75445-1.3	I128M	Neutral	0.172
USH2A	O75445-1.3	I128N	Pathogenic	0.851
USH2A	O75445-1.3	I128P	Pathogenic	0.71
USH2A	O75445-1.3	I128Q	Pathogenic	0.894
USH2A	O75445-1.3	I128R	Pathogenic	0.888
USH2A	O75445-1.3	I128S	Neutral	0.474
USH2A	O75445-1.3	I128T	Neutral	0.394
USH2A	O75445-1.3	I128V	Neutral	0.021
USH2A	O75445-1.3	I128W	Pathogenic	0.603
USH2A	O75445-1.3	I128Y	Neutral	0.418
USH2A	O75445-1.3	F129A	Pathogenic	0.954
USH2A	O75445-1.3	F129C	Pathogenic	0.965
USH2A	O75445-1.3	F129D	Pathogenic	0.994
USH2A	O75445-1.3	F129E	Pathogenic	0.997
USH2A	O75445-1.3	F129G	Pathogenic	0.968
USH2A	O75445-1.3	F129H	Pathogenic	0.981
USH2A	O75445-1.3	F129I	Pathogenic	0.923
USH2A	O75445-1.3	F129K	Pathogenic	0.999
USH2A	O75445-1.3	F129L	Pathogenic	0.926
USH2A	O75445-1.3	F129M	Pathogenic	0.94
USH2A	O75445-1.3	F129N	Pathogenic	0.995
USH2A	O75445-1.3	F129P	Pathogenic	0.995
USH2A	O75445-1.3	F129Q	Pathogenic	0.996
USH2A	O75445-1.3	F129R	Pathogenic	0.998
USH2A	O75445-1.3	F129S	Pathogenic	0.968
USH2A	O75445-1.3	F129T	Pathogenic	0.98
USH2A	O75445-1.3	F129V	Pathogenic	0.951
USH2A	O75445-1.3	F129W	Pathogenic	0.792
USH2A	O75445-1.3	F129Y	Pathogenic	0.639
USH2A	O75445-1.3	G130A	Neutral	0.048
USH2A	O75445-1.3	G130C	Neutral	0.314
USH2A	O75445-1.3	G130D	Neutral	0.063
USH2A	O75445-1.3	G130E	Neutral	0.075
USH2A	O75445-1.3	G130F	Neutral	0.124
USH2A	O75445-1.3	G130H	Neutral	0.045
USH2A	O75445-1.3	G130I	Neutral	0.317
USH2A	O75445-1.3	G130K	Neutral	0.04
USH2A	O75445-1.3	G130L	Neutral	0.306
USH2A	O75445-1.3	G130M	Neutral	0.133
USH2A	O75445-1.3	G130N	Neutral	0.023
USH2A	O75445-1.3	G130P	Neutral	0.134
USH2A	O75445-1.3	G130Q	Neutral	0.053
USH2A	O75445-1.3	G130R	Neutral	0.027
USH2A	O75445-1.3	G130S	Neutral	0.035
USH2A	O75445-1.3	G130T	Neutral	0.1
USH2A	O75445-1.3	G130V	Neutral	0.218
USH2A	O75445-1.3	G130W	Neutral	0.031
USH2A	O75445-1.3	G130Y	Neutral	0.072
USH2A	O75445-1.3	N131A	Neutral	0.298
USH2A	O75445-1.3	N131C	Pathogenic	0.714
USH2A	O75445-1.3	N131D	Neutral	0.051
USH2A	O75445-1.3	N131E	Neutral	0.081
USH2A	O75445-1.3	N131F	Pathogenic	0.595
USH2A	O75445-1.3	N131G	Neutral	0.037
USH2A	O75445-1.3	N131H	Neutral	0.039
USH2A	O75445-1.3	N131I	Pathogenic	0.678
USH2A	O75445-1.3	N131K	Neutral	0.044
USH2A	O75445-1.3	N131L	Pathogenic	0.667
USH2A	O75445-1.3	N131M	Neutral	0.41
USH2A	O75445-1.3	N131P	Pathogenic	0.521
USH2A	O75445-1.3	N131Q	Neutral	0.082
USH2A	O75445-1.3	N131R	Neutral	0.029
USH2A	O75445-1.3	N131S	Neutral	0.035
USH2A	O75445-1.3	N131T	Neutral	0.155
USH2A	O75445-1.3	N131V	Pathogenic	0.743
USH2A	O75445-1.3	N131W	Pathogenic	0.632
USH2A	O75445-1.3	N131Y	Neutral	0.26
USH2A	O75445-1.3	H132A	Neutral	0.147
USH2A	O75445-1.3	H132C	Pathogenic	0.504
USH2A	O75445-1.3	H132D	Neutral	0.19
USH2A	O75445-1.3	H132E	Neutral	0.147
USH2A	O75445-1.3	H132F	Neutral	0.32
USH2A	O75445-1.3	H132G	Neutral	0.084
USH2A	O75445-1.3	H132I	Pathogenic	0.779
USH2A	O75445-1.3	H132K	Neutral	0.265
USH2A	O75445-1.3	H132L	Pathogenic	0.77
USH2A	O75445-1.3	H132M	Pathogenic	0.537
USH2A	O75445-1.3	H132N	Neutral	0.046
USH2A	O75445-1.3	H132P	Neutral	0.308
USH2A	O75445-1.3	H132Q	Neutral	0.141
USH2A	O75445-1.3	H132R	Neutral	0.095
USH2A	O75445-1.3	H132S	Neutral	0.084
USH2A	O75445-1.3	H132T	Neutral	0.28
USH2A	O75445-1.3	H132V	Pathogenic	0.678
USH2A	O75445-1.3	H132W	Neutral	0.355
USH2A	O75445-1.3	H132Y	Neutral	0.021
USH2A	O75445-1.3	K133A	Neutral	0.101
USH2A	O75445-1.3	K133C	Pathogenic	0.602
USH2A	O75445-1.3	K133D	Neutral	0.125
USH2A	O75445-1.3	K133E	Neutral	0.049
USH2A	O75445-1.3	K133F	Pathogenic	0.916
USH2A	O75445-1.3	K133G	Neutral	0.107
USH2A	O75445-1.3	K133H	Neutral	0.347
USH2A	O75445-1.3	K133I	Pathogenic	0.885
USH2A	O75445-1.3	K133L	Pathogenic	0.762
USH2A	O75445-1.3	K133M	Pathogenic	0.526
USH2A	O75445-1.3	K133N	Neutral	0.074
USH2A	O75445-1.3	K133P	Neutral	0.224
USH2A	O75445-1.3	K133Q	Neutral	0.07
USH2A	O75445-1.3	K133R	Neutral	0.028
USH2A	O75445-1.3	K133S	Neutral	0.048
USH2A	O75445-1.3	K133T	Neutral	0.202
USH2A	O75445-1.3	K133V	Pathogenic	0.578
USH2A	O75445-1.3	K133W	Pathogenic	0.848
USH2A	O75445-1.3	K133Y	Pathogenic	0.722
USH2A	O75445-1.3	S134A	Neutral	0.006
USH2A	O75445-1.3	S134C	Neutral	0.032
USH2A	O75445-1.3	S134D	Neutral	0.011
USH2A	O75445-1.3	S134E	Neutral	0.006
USH2A	O75445-1.3	S134F	Neutral	0.023
USH2A	O75445-1.3	S134G	Neutral	0.006
USH2A	O75445-1.3	S134H	Neutral	0.008
USH2A	O75445-1.3	S134I	Neutral	0.033
USH2A	O75445-1.3	S134K	Neutral	0.003
USH2A	O75445-1.3	S134L	Neutral	0.031
USH2A	O75445-1.3	S134M	Neutral	0.011
USH2A	O75445-1.3	S134N	Neutral	0.004
USH2A	O75445-1.3	S134P	Neutral	0.025
USH2A	O75445-1.3	S134Q	Neutral	0.004
USH2A	O75445-1.3	S134R	Neutral	0.004
USH2A	O75445-1.3	S134T	Neutral	0.004
USH2A	O75445-1.3	S134V	Neutral	0.045
USH2A	O75445-1.3	S134W	Neutral	0.027
USH2A	O75445-1.3	S134Y	Neutral	0.013
USH2A	O75445-1.3	C135A	Pathogenic	0.944
USH2A	O75445-1.3	C135D	Pathogenic	0.998
USH2A	O75445-1.3	C135E	Pathogenic	0.998
USH2A	O75445-1.3	C135F	Pathogenic	0.973
USH2A	O75445-1.3	C135G	Pathogenic	0.992
USH2A	O75445-1.3	C135H	Pathogenic	0.993
USH2A	O75445-1.3	C135I	Pathogenic	0.958
USH2A	O75445-1.3	C135K	Pathogenic	0.993
USH2A	O75445-1.3	C135L	Pathogenic	0.956
USH2A	O75445-1.3	C135M	Pathogenic	0.945
USH2A	O75445-1.3	C135N	Pathogenic	0.998
USH2A	O75445-1.3	C135P	Pathogenic	0.996
USH2A	O75445-1.3	C135Q	Pathogenic	0.995
USH2A	O75445-1.3	C135R	Pathogenic	0.99
USH2A	O75445-1.3	C135S	Pathogenic	0.982
USH2A	O75445-1.3	C135T	Pathogenic	0.983
USH2A	O75445-1.3	C135V	Pathogenic	0.969
USH2A	O75445-1.3	C135W	Pathogenic	0.949
USH2A	O75445-1.3	C135Y	Pathogenic	0.953
USH2A	O75445-1.3	F136A	Neutral	0.341
USH2A	O75445-1.3	F136C	Neutral	0.406
USH2A	O75445-1.3	F136D	Pathogenic	0.814
USH2A	O75445-1.3	F136E	Pathogenic	0.879
USH2A	O75445-1.3	F136G	Neutral	0.428
USH2A	O75445-1.3	F136H	Pathogenic	0.56
USH2A	O75445-1.3	F136I	Neutral	0.23
USH2A	O75445-1.3	F136K	Pathogenic	0.952
USH2A	O75445-1.3	F136L	Neutral	0.237
USH2A	O75445-1.3	F136M	Neutral	0.282
USH2A	O75445-1.3	F136N	Pathogenic	0.825
USH2A	O75445-1.3	F136P	Pathogenic	0.822
USH2A	O75445-1.3	F136Q	Pathogenic	0.874
USH2A	O75445-1.3	F136R	Pathogenic	0.93
USH2A	O75445-1.3	F136S	Neutral	0.427
USH2A	O75445-1.3	F136T	Pathogenic	0.551
USH2A	O75445-1.3	F136V	Neutral	0.329
USH2A	O75445-1.3	F136W	Neutral	0.087
USH2A	O75445-1.3	F136Y	Neutral	0.042
USH2A	O75445-1.3	S137A	Neutral	0.021
USH2A	O75445-1.3	S137C	Neutral	0.11
USH2A	O75445-1.3	S137D	Neutral	0.039
USH2A	O75445-1.3	S137E	Neutral	0.021
USH2A	O75445-1.3	S137F	Neutral	0.081
USH2A	O75445-1.3	S137G	Neutral	0.022
USH2A	O75445-1.3	S137H	Neutral	0.028
USH2A	O75445-1.3	S137I	Neutral	0.112
USH2A	O75445-1.3	S137K	Neutral	0.011
USH2A	O75445-1.3	S137L	Neutral	0.107
USH2A	O75445-1.3	S137M	Neutral	0.04
USH2A	O75445-1.3	S137N	Neutral	0.014
USH2A	O75445-1.3	S137P	Neutral	0.087
USH2A	O75445-1.3	S137Q	Neutral	0.014
USH2A	O75445-1.3	S137R	Neutral	0.016
USH2A	O75445-1.3	S137T	Neutral	0.013
USH2A	O75445-1.3	S137V	Neutral	0.147
USH2A	O75445-1.3	S137W	Neutral	0.093
USH2A	O75445-1.3	S137Y	Neutral	0.046
USH2A	O75445-1.3	S138A	Neutral	0.092
USH2A	O75445-1.3	S138C	Neutral	0.371
USH2A	O75445-1.3	S138D	Neutral	0.16
USH2A	O75445-1.3	S138E	Neutral	0.091
USH2A	O75445-1.3	S138F	Neutral	0.294
USH2A	O75445-1.3	S138G	Neutral	0.097
USH2A	O75445-1.3	S138H	Neutral	0.121
USH2A	O75445-1.3	S138I	Neutral	0.374
USH2A	O75445-1.3	S138K	Neutral	0.049
USH2A	O75445-1.3	S138L	Neutral	0.362
USH2A	O75445-1.3	S138M	Neutral	0.164
USH2A	O75445-1.3	S138N	Neutral	0.061
USH2A	O75445-1.3	S138P	Neutral	0.312
USH2A	O75445-1.3	S138Q	Neutral	0.065
USH2A	O75445-1.3	S138R	Neutral	0.073
USH2A	O75445-1.3	S138T	Neutral	0.059
USH2A	O75445-1.3	S138V	Neutral	0.451
USH2A	O75445-1.3	S138W	Neutral	0.327
USH2A	O75445-1.3	S138Y	Neutral	0.185
USH2A	O75445-1.3	P139A	Pathogenic	0.673
USH2A	O75445-1.3	P139C	Pathogenic	0.948
USH2A	O75445-1.3	P139D	Pathogenic	0.877
USH2A	O75445-1.3	P139E	Pathogenic	0.789
USH2A	O75445-1.3	P139F	Pathogenic	0.944
USH2A	O75445-1.3	P139G	Pathogenic	0.748
USH2A	O75445-1.3	P139H	Pathogenic	0.813
USH2A	O75445-1.3	P139I	Pathogenic	0.913
USH2A	O75445-1.3	P139K	Pathogenic	0.659
USH2A	O75445-1.3	P139L	Pathogenic	0.909
USH2A	O75445-1.3	P139M	Pathogenic	0.776
USH2A	O75445-1.3	P139N	Pathogenic	0.927
USH2A	O75445-1.3	P139Q	Pathogenic	0.721
USH2A	O75445-1.3	P139R	Pathogenic	0.745
USH2A	O75445-1.3	P139S	Pathogenic	0.747
USH2A	O75445-1.3	P139T	Pathogenic	0.8
USH2A	O75445-1.3	P139V	Pathogenic	0.864
USH2A	O75445-1.3	P139W	Pathogenic	0.895
USH2A	O75445-1.3	P139Y	Pathogenic	0.8
USH2A	O75445-1.3	P140A	Neutral	0.121
USH2A	O75445-1.3	P140C	Pathogenic	0.552
USH2A	O75445-1.3	P140D	Neutral	0.324
USH2A	O75445-1.3	P140E	Neutral	0.201
USH2A	O75445-1.3	P140F	Pathogenic	0.53
USH2A	O75445-1.3	P140G	Neutral	0.167
USH2A	O75445-1.3	P140H	Neutral	0.227
USH2A	O75445-1.3	P140I	Neutral	0.414
USH2A	O75445-1.3	P140K	Neutral	0.115
USH2A	O75445-1.3	P140L	Neutral	0.402
USH2A	O75445-1.3	P140M	Neutral	0.189
USH2A	O75445-1.3	P140N	Neutral	0.461
USH2A	O75445-1.3	P140Q	Neutral	0.148
USH2A	O75445-1.3	P140R	Neutral	0.164
USH2A	O75445-1.3	P140S	Neutral	0.166
USH2A	O75445-1.3	P140T	Neutral	0.212
USH2A	O75445-1.3	P140V	Neutral	0.299
USH2A	O75445-1.3	P140W	Neutral	0.366
USH2A	O75445-1.3	P140Y	Neutral	0.212
USH2A	O75445-1.3	S141A	Neutral	0.023
USH2A	O75445-1.3	S141C	Neutral	0.12
USH2A	O75445-1.3	S141D	Neutral	0.042
USH2A	O75445-1.3	S141E	Neutral	0.023
USH2A	O75445-1.3	S141F	Neutral	0.088
USH2A	O75445-1.3	S141G	Neutral	0.024
USH2A	O75445-1.3	S141H	Neutral	0.031
USH2A	O75445-1.3	S141I	Neutral	0.122
USH2A	O75445-1.3	S141K	Neutral	0.012
USH2A	O75445-1.3	S141L	Neutral	0.116
USH2A	O75445-1.3	S141M	Neutral	0.044
USH2A	O75445-1.3	S141N	Neutral	0.015
USH2A	O75445-1.3	S141P	Neutral	0.095
USH2A	O75445-1.3	S141Q	Neutral	0.016
USH2A	O75445-1.3	S141R	Neutral	0.018
USH2A	O75445-1.3	S141T	Neutral	0.014
USH2A	O75445-1.3	S141V	Neutral	0.16
USH2A	O75445-1.3	S141W	Neutral	0.101
USH2A	O75445-1.3	S141Y	Neutral	0.05
USH2A	O75445-1.3	P142A	Neutral	0.159
USH2A	O75445-1.3	P142C	Pathogenic	0.628
USH2A	O75445-1.3	P142D	Neutral	0.396
USH2A	O75445-1.3	P142E	Neutral	0.256
USH2A	O75445-1.3	P142F	Pathogenic	0.607
USH2A	O75445-1.3	P142G	Neutral	0.215
USH2A	O75445-1.3	P142H	Neutral	0.287
USH2A	O75445-1.3	P142I	Neutral	0.492
USH2A	O75445-1.3	P142K	Neutral	0.151
USH2A	O75445-1.3	P142L	Neutral	0.48
USH2A	O75445-1.3	P142M	Neutral	0.242
USH2A	O75445-1.3	P142N	Pathogenic	0.54
USH2A	O75445-1.3	P142Q	Neutral	0.193
USH2A	O75445-1.3	P142R	Neutral	0.212
USH2A	O75445-1.3	P142S	Neutral	0.214
USH2A	O75445-1.3	P142T	Neutral	0.27
USH2A	O75445-1.3	P142V	Neutral	0.369
USH2A	O75445-1.3	P142W	Neutral	0.441
USH2A	O75445-1.3	P142Y	Neutral	0.27
USH2A	O75445-1.3	K143A	Neutral	0.01
USH2A	O75445-1.3	K143C	Neutral	0.115
USH2A	O75445-1.3	K143D	Neutral	0.012
USH2A	O75445-1.3	K143E	Neutral	0.004
USH2A	O75445-1.3	K143F	Neutral	0.482
USH2A	O75445-1.3	K143G	Neutral	0.01
USH2A	O75445-1.3	K143H	Neutral	0.043
USH2A	O75445-1.3	K143I	Neutral	0.397
USH2A	O75445-1.3	K143L	Neutral	0.215
USH2A	O75445-1.3	K143M	Neutral	0.087
USH2A	O75445-1.3	K143N	Neutral	0.007
USH2A	O75445-1.3	K143P	Neutral	0.024
USH2A	O75445-1.3	K143Q	Neutral	0.006
USH2A	O75445-1.3	K143R	Neutral	0.002
USH2A	O75445-1.3	K143S	Neutral	0.004
USH2A	O75445-1.3	K143T	Neutral	0.021
USH2A	O75445-1.3	K143V	Neutral	0.105
USH2A	O75445-1.3	K143W	Neutral	0.323
USH2A	O75445-1.3	K143Y	Neutral	0.182
USH2A	O75445-1.3	L144A	Pathogenic	0.519
USH2A	O75445-1.3	L144C	Pathogenic	0.587
USH2A	O75445-1.3	L144D	Pathogenic	0.979
USH2A	O75445-1.3	L144E	Pathogenic	0.972
USH2A	O75445-1.3	L144F	Pathogenic	0.52
USH2A	O75445-1.3	L144G	Pathogenic	0.891
USH2A	O75445-1.3	L144H	Pathogenic	0.969
USH2A	O75445-1.3	L144I	Neutral	0.23
USH2A	O75445-1.3	L144K	Pathogenic	0.954
USH2A	O75445-1.3	L144M	Neutral	0.263
USH2A	O75445-1.3	L144N	Pathogenic	0.957
USH2A	O75445-1.3	L144P	Pathogenic	0.906
USH2A	O75445-1.3	L144Q	Pathogenic	0.935
USH2A	O75445-1.3	L144R	Pathogenic	0.932
USH2A	O75445-1.3	L144S	Pathogenic	0.78
USH2A	O75445-1.3	L144T	Pathogenic	0.719
USH2A	O75445-1.3	L144V	Neutral	0.309
USH2A	O75445-1.3	L144W	Pathogenic	0.743
USH2A	O75445-1.3	L144Y	Pathogenic	0.738
USH2A	O75445-1.3	M145A	Neutral	0.014
USH2A	O75445-1.3	M145C	Neutral	0.018
USH2A	O75445-1.3	M145D	Neutral	0.21
USH2A	O75445-1.3	M145E	Neutral	0.163
USH2A	O75445-1.3	M145F	Neutral	0.022
USH2A	O75445-1.3	M145G	Neutral	0.044
USH2A	O75445-1.3	M145H	Neutral	0.151
USH2A	O75445-1.3	M145I	Neutral	0.014
USH2A	O75445-1.3	M145K	Neutral	0.104
USH2A	O75445-1.3	M145L	Neutral	0.006
USH2A	O75445-1.3	M145N	Neutral	0.112
USH2A	O75445-1.3	M145P	Neutral	0.051
USH2A	O75445-1.3	M145Q	Neutral	0.034
USH2A	O75445-1.3	M145R	Neutral	0.071
USH2A	O75445-1.3	M145S	Neutral	0.02
USH2A	O75445-1.3	M145T	Neutral	0.032
USH2A	O75445-1.3	M145V	Neutral	0.006
USH2A	O75445-1.3	M145W	Neutral	0.025
USH2A	O75445-1.3	M145Y	Neutral	0.035
USH2A	O75445-1.3	A146C	Neutral	0.13
USH2A	O75445-1.3	A146D	Neutral	0.448
USH2A	O75445-1.3	A146E	Neutral	0.157
USH2A	O75445-1.3	A146F	Neutral	0.194
USH2A	O75445-1.3	A146G	Neutral	0.111
USH2A	O75445-1.3	A146H	Neutral	0.179
USH2A	O75445-1.3	A146I	Neutral	0.131
USH2A	O75445-1.3	A146K	Neutral	0.088
USH2A	O75445-1.3	A146L	Neutral	0.126
USH2A	O75445-1.3	A146M	Neutral	0.102
USH2A	O75445-1.3	A146N	Neutral	0.388
USH2A	O75445-1.3	A146P	Neutral	0.208
USH2A	O75445-1.3	A146Q	Neutral	0.114
USH2A	O75445-1.3	A146R	Neutral	0.06
USH2A	O75445-1.3	A146S	Neutral	0.078
USH2A	O75445-1.3	A146T	Neutral	0.08
USH2A	O75445-1.3	A146V	Neutral	0.084
USH2A	O75445-1.3	A146W	Neutral	0.22
USH2A	O75445-1.3	A146Y	Neutral	0.116
USH2A	O75445-1.3	S147A	Neutral	0.155
USH2A	O75445-1.3	S147C	Pathogenic	0.517
USH2A	O75445-1.3	S147D	Neutral	0.257
USH2A	O75445-1.3	S147E	Neutral	0.154
USH2A	O75445-1.3	S147F	Neutral	0.431
USH2A	O75445-1.3	S147G	Neutral	0.164
USH2A	O75445-1.3	S147H	Neutral	0.201
USH2A	O75445-1.3	S147I	Pathogenic	0.52
USH2A	O75445-1.3	S147K	Neutral	0.086
USH2A	O75445-1.3	S147L	Pathogenic	0.508
USH2A	O75445-1.3	S147M	Neutral	0.263
USH2A	O75445-1.3	S147N	Neutral	0.106
USH2A	O75445-1.3	S147P	Neutral	0.452
USH2A	O75445-1.3	S147Q	Neutral	0.112
USH2A	O75445-1.3	S147R	Neutral	0.125
USH2A	O75445-1.3	S147T	Neutral	0.103
USH2A	O75445-1.3	S147V	Pathogenic	0.599
USH2A	O75445-1.3	S147W	Neutral	0.469
USH2A	O75445-1.3	S147Y	Neutral	0.293
USH2A	O75445-1.3	F148A	Pathogenic	0.824
USH2A	O75445-1.3	F148C	Pathogenic	0.86
USH2A	O75445-1.3	F148D	Pathogenic	0.975
USH2A	O75445-1.3	F148E	Pathogenic	0.985
USH2A	O75445-1.3	F148G	Pathogenic	0.871
USH2A	O75445-1.3	F148H	Pathogenic	0.92
USH2A	O75445-1.3	F148I	Pathogenic	0.73
USH2A	O75445-1.3	F148K	Pathogenic	0.994
USH2A	O75445-1.3	F148L	Pathogenic	0.737
USH2A	O75445-1.3	F148M	Pathogenic	0.779
USH2A	O75445-1.3	F148N	Pathogenic	0.977
USH2A	O75445-1.3	F148P	Pathogenic	0.977
USH2A	O75445-1.3	F148Q	Pathogenic	0.984
USH2A	O75445-1.3	F148R	Pathogenic	0.992
USH2A	O75445-1.3	F148S	Pathogenic	0.871
USH2A	O75445-1.3	F148T	Pathogenic	0.917
USH2A	O75445-1.3	F148V	Pathogenic	0.815
USH2A	O75445-1.3	F148W	Neutral	0.461
USH2A	O75445-1.3	F148Y	Neutral	0.285
USH2A	O75445-1.3	T149A	Pathogenic	0.537
USH2A	O75445-1.3	T149C	Pathogenic	0.872
USH2A	O75445-1.3	T149D	Pathogenic	0.903
USH2A	O75445-1.3	T149E	Pathogenic	0.847
USH2A	O75445-1.3	T149F	Pathogenic	0.883
USH2A	O75445-1.3	T149G	Pathogenic	0.784
USH2A	O75445-1.3	T149H	Pathogenic	0.866
USH2A	O75445-1.3	T149I	Pathogenic	0.826
USH2A	O75445-1.3	T149K	Pathogenic	0.741
USH2A	O75445-1.3	T149L	Pathogenic	0.818
USH2A	O75445-1.3	T149M	Pathogenic	0.781
USH2A	O75445-1.3	T149N	Pathogenic	0.784
USH2A	O75445-1.3	T149P	Pathogenic	0.872
USH2A	O75445-1.3	T149Q	Pathogenic	0.793
USH2A	O75445-1.3	T149R	Pathogenic	0.655
USH2A	O75445-1.3	T149S	Neutral	0.41
USH2A	O75445-1.3	T149V	Pathogenic	0.74
USH2A	O75445-1.3	T149W	Pathogenic	0.794
USH2A	O75445-1.3	T149Y	Pathogenic	0.805
USH2A	O75445-1.3	L150A	Pathogenic	0.779
USH2A	O75445-1.3	L150C	Pathogenic	0.823
USH2A	O75445-1.3	L150D	Pathogenic	0.994
USH2A	O75445-1.3	L150E	Pathogenic	0.991
USH2A	O75445-1.3	L150F	Pathogenic	0.779
USH2A	O75445-1.3	L150G	Pathogenic	0.964
USH2A	O75445-1.3	L150H	Pathogenic	0.99
USH2A	O75445-1.3	L150I	Neutral	0.493
USH2A	O75445-1.3	L150K	Pathogenic	0.985
USH2A	O75445-1.3	L150M	Pathogenic	0.538
USH2A	O75445-1.3	L150N	Pathogenic	0.987
USH2A	O75445-1.3	L150P	Pathogenic	0.969
USH2A	O75445-1.3	L150Q	Pathogenic	0.979
USH2A	O75445-1.3	L150R	Pathogenic	0.978
USH2A	O75445-1.3	L150S	Pathogenic	0.92
USH2A	O75445-1.3	L150T	Pathogenic	0.893
USH2A	O75445-1.3	L150V	Pathogenic	0.593
USH2A	O75445-1.3	L150W	Pathogenic	0.904
USH2A	O75445-1.3	L150Y	Pathogenic	0.902
USH2A	O75445-1.3	A151C	Neutral	0.477
USH2A	O75445-1.3	A151D	Pathogenic	0.832
USH2A	O75445-1.3	A151E	Pathogenic	0.532
USH2A	O75445-1.3	A151F	Pathogenic	0.595
USH2A	O75445-1.3	A151G	Neutral	0.432
USH2A	O75445-1.3	A151H	Pathogenic	0.57
USH2A	O75445-1.3	A151I	Neutral	0.48
USH2A	O75445-1.3	A151K	Neutral	0.37
USH2A	O75445-1.3	A151L	Neutral	0.467
USH2A	O75445-1.3	A151M	Neutral	0.41
USH2A	O75445-1.3	A151N	Pathogenic	0.795
USH2A	O75445-1.3	A151P	Pathogenic	0.616
USH2A	O75445-1.3	A151Q	Neutral	0.44
USH2A	O75445-1.3	A151R	Neutral	0.281
USH2A	O75445-1.3	A151S	Neutral	0.34
USH2A	O75445-1.3	A151T	Neutral	0.348
USH2A	O75445-1.3	A151V	Neutral	0.357
USH2A	O75445-1.3	A151W	Pathogenic	0.632
USH2A	O75445-1.3	A151Y	Neutral	0.445
USH2A	O75445-1.3	V152A	Pathogenic	0.537
USH2A	O75445-1.3	V152C	Pathogenic	0.777
USH2A	O75445-1.3	V152D	Pathogenic	0.981
USH2A	O75445-1.3	V152E	Pathogenic	0.966
USH2A	O75445-1.3	V152F	Pathogenic	0.743
USH2A	O75445-1.3	V152G	Pathogenic	0.897
USH2A	O75445-1.3	V152H	Pathogenic	0.971
USH2A	O75445-1.3	V152I	Neutral	0.132
USH2A	O75445-1.3	V152K	Pathogenic	0.937
USH2A	O75445-1.3	V152L	Neutral	0.43
USH2A	O75445-1.3	V152M	Neutral	0.374
USH2A	O75445-1.3	V152N	Pathogenic	0.982
USH2A	O75445-1.3	V152P	Pathogenic	0.912
USH2A	O75445-1.3	V152Q	Pathogenic	0.952
USH2A	O75445-1.3	V152R	Pathogenic	0.958
USH2A	O75445-1.3	V152S	Pathogenic	0.897
USH2A	O75445-1.3	V152T	Pathogenic	0.732
USH2A	O75445-1.3	V152W	Pathogenic	0.885
USH2A	O75445-1.3	V152Y	Pathogenic	0.671
USH2A	O75445-1.3	W153A	Pathogenic	0.985
USH2A	O75445-1.3	W153C	Pathogenic	0.975
USH2A	O75445-1.3	W153D	Pathogenic	0.998
USH2A	O75445-1.3	W153E	Pathogenic	0.998
USH2A	O75445-1.3	W153F	Pathogenic	0.912
USH2A	O75445-1.3	W153G	Pathogenic	0.949
USH2A	O75445-1.3	W153H	Pathogenic	0.994
USH2A	O75445-1.3	W153I	Pathogenic	0.995
USH2A	O75445-1.3	W153K	Pathogenic	0.999
USH2A	O75445-1.3	W153L	Pathogenic	0.989
USH2A	O75445-1.3	W153M	Pathogenic	0.98
USH2A	O75445-1.3	W153N	Pathogenic	0.998
USH2A	O75445-1.3	W153P	Pathogenic	0.996
USH2A	O75445-1.3	W153Q	Pathogenic	0.994
USH2A	O75445-1.3	W153R	Pathogenic	0.999
USH2A	O75445-1.3	W153S	Pathogenic	0.99
USH2A	O75445-1.3	W153T	Pathogenic	0.986
USH2A	O75445-1.3	W153V	Pathogenic	0.993
USH2A	O75445-1.3	W153Y	Pathogenic	0.893
USH2A	O75445-1.3	L154A	Pathogenic	0.539
USH2A	O75445-1.3	L154C	Pathogenic	0.606
USH2A	O75445-1.3	L154D	Pathogenic	0.981
USH2A	O75445-1.3	L154E	Pathogenic	0.974
USH2A	O75445-1.3	L154F	Pathogenic	0.54
USH2A	O75445-1.3	L154G	Pathogenic	0.898
USH2A	O75445-1.3	L154H	Pathogenic	0.972
USH2A	O75445-1.3	L154I	Neutral	0.244
USH2A	O75445-1.3	L154K	Pathogenic	0.957
USH2A	O75445-1.3	L154M	Neutral	0.279
USH2A	O75445-1.3	L154N	Pathogenic	0.96
USH2A	O75445-1.3	L154P	Pathogenic	0.912
USH2A	O75445-1.3	L154Q	Pathogenic	0.94
USH2A	O75445-1.3	L154R	Pathogenic	0.937
USH2A	O75445-1.3	L154S	Pathogenic	0.793
USH2A	O75445-1.3	L154T	Pathogenic	0.734
USH2A	O75445-1.3	L154V	Neutral	0.326
USH2A	O75445-1.3	L154W	Pathogenic	0.758
USH2A	O75445-1.3	L154Y	Pathogenic	0.753
USH2A	O75445-1.3	K155A	Pathogenic	0.814
USH2A	O75445-1.3	K155C	Pathogenic	0.983
USH2A	O75445-1.3	K155D	Pathogenic	0.847
USH2A	O75445-1.3	K155E	Pathogenic	0.669
USH2A	O75445-1.3	K155F	Pathogenic	0.998
USH2A	O75445-1.3	K155G	Pathogenic	0.823
USH2A	O75445-1.3	K155H	Pathogenic	0.954
USH2A	O75445-1.3	K155I	Pathogenic	0.997
USH2A	O75445-1.3	K155L	Pathogenic	0.992
USH2A	O75445-1.3	K155M	Pathogenic	0.977
USH2A	O75445-1.3	K155N	Pathogenic	0.756
USH2A	O75445-1.3	K155P	Pathogenic	0.918
USH2A	O75445-1.3	K155Q	Pathogenic	0.745
USH2A	O75445-1.3	K155R	Pathogenic	0.532
USH2A	O75445-1.3	K155S	Pathogenic	0.662
USH2A	O75445-1.3	K155T	Pathogenic	0.908
USH2A	O75445-1.3	K155V	Pathogenic	0.982
USH2A	O75445-1.3	K155W	Pathogenic	0.995
USH2A	O75445-1.3	K155Y	Pathogenic	0.99
USH2A	O75445-1.3	P156A	Pathogenic	0.532
USH2A	O75445-1.3	P156C	Pathogenic	0.91
USH2A	O75445-1.3	P156D	Pathogenic	0.797
USH2A	O75445-1.3	P156E	Pathogenic	0.674
USH2A	O75445-1.3	P156F	Pathogenic	0.903
USH2A	O75445-1.3	P156G	Pathogenic	0.622
USH2A	O75445-1.3	P156H	Pathogenic	0.707
USH2A	O75445-1.3	P156I	Pathogenic	0.853
USH2A	O75445-1.3	P156K	Pathogenic	0.517
USH2A	O75445-1.3	P156L	Pathogenic	0.847
USH2A	O75445-1.3	P156M	Pathogenic	0.657
USH2A	O75445-1.3	P156N	Pathogenic	0.876
USH2A	O75445-1.3	P156Q	Pathogenic	0.589
USH2A	O75445-1.3	P156R	Pathogenic	0.618
USH2A	O75445-1.3	P156S	Pathogenic	0.621
USH2A	O75445-1.3	P156T	Pathogenic	0.689
USH2A	O75445-1.3	P156V	Pathogenic	0.778
USH2A	O75445-1.3	P156W	Pathogenic	0.826
USH2A	O75445-1.3	P156Y	Pathogenic	0.689
USH2A	O75445-1.3	E157A	Pathogenic	0.521
USH2A	O75445-1.3	E157C	Pathogenic	0.971
USH2A	O75445-1.3	E157D	Neutral	0.117
USH2A	O75445-1.3	E157F	Pathogenic	0.952
USH2A	O75445-1.3	E157G	Pathogenic	0.537
USH2A	O75445-1.3	E157H	Pathogenic	0.558
USH2A	O75445-1.3	E157I	Pathogenic	0.966
USH2A	O75445-1.3	E157K	Neutral	0.206
USH2A	O75445-1.3	E157L	Pathogenic	0.964
USH2A	O75445-1.3	E157M	Pathogenic	0.904
USH2A	O75445-1.3	E157N	Neutral	0.435
USH2A	O75445-1.3	E157P	Pathogenic	0.737
USH2A	O75445-1.3	E157Q	Neutral	0.188
USH2A	O75445-1.3	E157R	Neutral	0.283
USH2A	O75445-1.3	E157S	Neutral	0.328
USH2A	O75445-1.3	E157T	Pathogenic	0.71
USH2A	O75445-1.3	E157V	Pathogenic	0.93
USH2A	O75445-1.3	E157W	Pathogenic	0.91
USH2A	O75445-1.3	E157Y	Pathogenic	0.826
USH2A	O75445-1.3	Q158A	Neutral	0.088
USH2A	O75445-1.3	Q158C	Pathogenic	0.565
USH2A	O75445-1.3	Q158D	Neutral	0.085
USH2A	O75445-1.3	Q158E	Neutral	0.029
USH2A	O75445-1.3	Q158F	Pathogenic	0.709
USH2A	O75445-1.3	Q158G	Neutral	0.094
USH2A	O75445-1.3	Q158H	Neutral	0.134
USH2A	O75445-1.3	Q158I	Pathogenic	0.777
USH2A	O75445-1.3	Q158K	Neutral	0.046
USH2A	O75445-1.3	Q158L	Pathogenic	0.592
USH2A	O75445-1.3	Q158M	Neutral	0.181
USH2A	O75445-1.3	Q158N	Neutral	0.091
USH2A	O75445-1.3	Q158P	Neutral	0.199
USH2A	O75445-1.3	Q158R	Neutral	0.031
USH2A	O75445-1.3	Q158S	Neutral	0.042
USH2A	O75445-1.3	Q158T	Neutral	0.179
USH2A	O75445-1.3	Q158V	Pathogenic	0.541
USH2A	O75445-1.3	Q158W	Neutral	0.353
USH2A	O75445-1.3	Q158Y	Neutral	0.203
USH2A	O75445-1.3	Q159A	Neutral	0.006
USH2A	O75445-1.3	Q159C	Neutral	0.08
USH2A	O75445-1.3	Q159D	Neutral	0.006
USH2A	O75445-1.3	Q159E	Neutral	0.002
USH2A	O75445-1.3	Q159F	Neutral	0.139
USH2A	O75445-1.3	Q159G	Neutral	0.007
USH2A	O75445-1.3	Q159H	Neutral	0.01
USH2A	O75445-1.3	Q159I	Neutral	0.188
USH2A	O75445-1.3	Q159K	Neutral	0.003
USH2A	O75445-1.3	Q159L	Neutral	0.088
USH2A	O75445-1.3	Q159M	Neutral	0.014
USH2A	O75445-1.3	Q159N	Neutral	0.007
USH2A	O75445-1.3	Q159P	Neutral	0.016
USH2A	O75445-1.3	Q159R	Neutral	0.002
USH2A	O75445-1.3	Q159S	Neutral	0.003
USH2A	O75445-1.3	Q159T	Neutral	0.014
USH2A	O75445-1.3	Q159V	Neutral	0.073
USH2A	O75445-1.3	Q159W	Neutral	0.035
USH2A	O75445-1.3	Q159Y	Neutral	0.017
USH2A	O75445-1.3	G160A	Neutral	0.366
USH2A	O75445-1.3	G160C	Pathogenic	0.839
USH2A	O75445-1.3	G160D	Neutral	0.434
USH2A	O75445-1.3	G160E	Neutral	0.479
USH2A	O75445-1.3	G160F	Pathogenic	0.618
USH2A	O75445-1.3	G160H	Neutral	0.349
USH2A	O75445-1.3	G160I	Pathogenic	0.841
USH2A	O75445-1.3	G160K	Neutral	0.322
USH2A	O75445-1.3	G160L	Pathogenic	0.834
USH2A	O75445-1.3	G160M	Pathogenic	0.636
USH2A	O75445-1.3	G160N	Neutral	0.208
USH2A	O75445-1.3	G160P	Pathogenic	0.638
USH2A	O75445-1.3	G160Q	Neutral	0.389
USH2A	O75445-1.3	G160R	Neutral	0.24
USH2A	O75445-1.3	G160S	Neutral	0.294
USH2A	O75445-1.3	G160T	Pathogenic	0.56
USH2A	O75445-1.3	G160V	Pathogenic	0.761
USH2A	O75445-1.3	G160W	Neutral	0.266
USH2A	O75445-1.3	G160Y	Neutral	0.469
USH2A	O75445-1.3	V161A	Neutral	0.183
USH2A	O75445-1.3	V161C	Neutral	0.403
USH2A	O75445-1.3	V161D	Pathogenic	0.908
USH2A	O75445-1.3	V161E	Pathogenic	0.848
USH2A	O75445-1.3	V161F	Neutral	0.359
USH2A	O75445-1.3	V161G	Pathogenic	0.629
USH2A	O75445-1.3	V161H	Pathogenic	0.867
USH2A	O75445-1.3	V161I	Neutral	0.029
USH2A	O75445-1.3	V161K	Pathogenic	0.743
USH2A	O75445-1.3	V161L	Neutral	0.128
USH2A	O75445-1.3	V161M	Neutral	0.104
USH2A	O75445-1.3	V161N	Pathogenic	0.914
USH2A	O75445-1.3	V161P	Pathogenic	0.667
USH2A	O75445-1.3	V161Q	Pathogenic	0.794
USH2A	O75445-1.3	V161R	Pathogenic	0.814
USH2A	O75445-1.3	V161S	Pathogenic	0.628
USH2A	O75445-1.3	V161T	Neutral	0.347
USH2A	O75445-1.3	V161W	Pathogenic	0.599
USH2A	O75445-1.3	V161Y	Neutral	0.283
USH2A	O75445-1.3	M162A	Pathogenic	0.95
USH2A	O75445-1.3	M162C	Pathogenic	0.962
USH2A	O75445-1.3	M162D	Pathogenic	0.997
USH2A	O75445-1.3	M162E	Pathogenic	0.996
USH2A	O75445-1.3	M162F	Pathogenic	0.968
USH2A	O75445-1.3	M162G	Pathogenic	0.984
USH2A	O75445-1.3	M162H	Pathogenic	0.996
USH2A	O75445-1.3	M162I	Pathogenic	0.951
USH2A	O75445-1.3	M162K	Pathogenic	0.994
USH2A	O75445-1.3	M162L	Pathogenic	0.889
USH2A	O75445-1.3	M162N	Pathogenic	0.994
USH2A	O75445-1.3	M162P	Pathogenic	0.987
USH2A	O75445-1.3	M162Q	Pathogenic	0.98
USH2A	O75445-1.3	M162R	Pathogenic	0.991
USH2A	O75445-1.3	M162S	Pathogenic	0.965
USH2A	O75445-1.3	M162T	Pathogenic	0.978
USH2A	O75445-1.3	M162V	Pathogenic	0.888
USH2A	O75445-1.3	M162W	Pathogenic	0.973
USH2A	O75445-1.3	M162Y	Pathogenic	0.98
USH2A	O75445-1.3	C163A	Pathogenic	0.563
USH2A	O75445-1.3	C163D	Pathogenic	0.976
USH2A	O75445-1.3	C163E	Pathogenic	0.98
USH2A	O75445-1.3	C163F	Pathogenic	0.732
USH2A	O75445-1.3	C163G	Pathogenic	0.907
USH2A	O75445-1.3	C163H	Pathogenic	0.917
USH2A	O75445-1.3	C163I	Pathogenic	0.632
USH2A	O75445-1.3	C163K	Pathogenic	0.918
USH2A	O75445-1.3	C163L	Pathogenic	0.62
USH2A	O75445-1.3	C163M	Pathogenic	0.564
USH2A	O75445-1.3	C163N	Pathogenic	0.97
USH2A	O75445-1.3	C163P	Pathogenic	0.953
USH2A	O75445-1.3	C163Q	Pathogenic	0.937
USH2A	O75445-1.3	C163R	Pathogenic	0.881
USH2A	O75445-1.3	C163S	Pathogenic	0.809
USH2A	O75445-1.3	C163T	Pathogenic	0.816
USH2A	O75445-1.3	C163V	Pathogenic	0.703
USH2A	O75445-1.3	C163W	Pathogenic	0.583
USH2A	O75445-1.3	C163Y	Pathogenic	0.604
USH2A	O75445-1.3	V164A	Neutral	0.166
USH2A	O75445-1.3	V164C	Neutral	0.374
USH2A	O75445-1.3	V164D	Pathogenic	0.897
USH2A	O75445-1.3	V164E	Pathogenic	0.832
USH2A	O75445-1.3	V164F	Neutral	0.332
USH2A	O75445-1.3	V164G	Pathogenic	0.6
USH2A	O75445-1.3	V164H	Pathogenic	0.852
USH2A	O75445-1.3	V164I	Neutral	0.026
USH2A	O75445-1.3	V164K	Pathogenic	0.719
USH2A	O75445-1.3	V164L	Neutral	0.115
USH2A	O75445-1.3	V164M	Neutral	0.093
USH2A	O75445-1.3	V164N	Pathogenic	0.904
USH2A	O75445-1.3	V164P	Pathogenic	0.639
USH2A	O75445-1.3	V164Q	Pathogenic	0.774
USH2A	O75445-1.3	V164R	Pathogenic	0.795
USH2A	O75445-1.3	V164S	Pathogenic	0.599
USH2A	O75445-1.3	V164T	Neutral	0.32
USH2A	O75445-1.3	V164W	Pathogenic	0.57
USH2A	O75445-1.3	V164Y	Neutral	0.259
USH2A	O75445-1.3	I165A	Neutral	0.481
USH2A	O75445-1.3	I165C	Pathogenic	0.549
USH2A	O75445-1.3	I165D	Pathogenic	0.947
USH2A	O75445-1.3	I165E	Pathogenic	0.968
USH2A	O75445-1.3	I165F	Neutral	0.46
USH2A	O75445-1.3	I165G	Pathogenic	0.875
USH2A	O75445-1.3	I165H	Pathogenic	0.964
USH2A	O75445-1.3	I165K	Pathogenic	0.976
USH2A	O75445-1.3	I165L	Neutral	0.195
USH2A	O75445-1.3	I165M	Neutral	0.412
USH2A	O75445-1.3	I165N	Pathogenic	0.951
USH2A	O75445-1.3	I165P	Pathogenic	0.892
USH2A	O75445-1.3	I165Q	Pathogenic	0.966
USH2A	O75445-1.3	I165R	Pathogenic	0.964
USH2A	O75445-1.3	I165S	Pathogenic	0.753
USH2A	O75445-1.3	I165T	Pathogenic	0.687
USH2A	O75445-1.3	I165V	Neutral	0.068
USH2A	O75445-1.3	I165W	Pathogenic	0.836
USH2A	O75445-1.3	I165Y	Pathogenic	0.708
USH2A	O75445-1.3	E166A	Pathogenic	0.925
USH2A	O75445-1.3	E166C	Pathogenic	0.997
USH2A	O75445-1.3	E166D	Pathogenic	0.599
USH2A	O75445-1.3	E166F	Pathogenic	0.996
USH2A	O75445-1.3	E166G	Pathogenic	0.929
USH2A	O75445-1.3	E166H	Pathogenic	0.935
USH2A	O75445-1.3	E166I	Pathogenic	0.997
USH2A	O75445-1.3	E166K	Pathogenic	0.747
USH2A	O75445-1.3	E166L	Pathogenic	0.997
USH2A	O75445-1.3	E166M	Pathogenic	0.991
USH2A	O75445-1.3	E166N	Pathogenic	0.897
USH2A	O75445-1.3	E166P	Pathogenic	0.969
USH2A	O75445-1.3	E166Q	Pathogenic	0.724
USH2A	O75445-1.3	E166R	Pathogenic	0.817
USH2A	O75445-1.3	E166S	Pathogenic	0.847
USH2A	O75445-1.3	E166T	Pathogenic	0.965
USH2A	O75445-1.3	E166V	Pathogenic	0.993
USH2A	O75445-1.3	E166W	Pathogenic	0.991
USH2A	O75445-1.3	E166Y	Pathogenic	0.982
USH2A	O75445-1.3	K167A	Pathogenic	0.782
USH2A	O75445-1.3	K167C	Pathogenic	0.98
USH2A	O75445-1.3	K167D	Pathogenic	0.819
USH2A	O75445-1.3	K167E	Pathogenic	0.623
USH2A	O75445-1.3	K167F	Pathogenic	0.997
USH2A	O75445-1.3	K167G	Pathogenic	0.792
USH2A	O75445-1.3	K167H	Pathogenic	0.944
USH2A	O75445-1.3	K167I	Pathogenic	0.996
USH2A	O75445-1.3	K167L	Pathogenic	0.99
USH2A	O75445-1.3	K167M	Pathogenic	0.973
USH2A	O75445-1.3	K167N	Pathogenic	0.717
USH2A	O75445-1.3	K167P	Pathogenic	0.902
USH2A	O75445-1.3	K167Q	Pathogenic	0.705
USH2A	O75445-1.3	K167R	Neutral	0.482
USH2A	O75445-1.3	K167S	Pathogenic	0.616
USH2A	O75445-1.3	K167T	Pathogenic	0.89
USH2A	O75445-1.3	K167V	Pathogenic	0.978
USH2A	O75445-1.3	K167W	Pathogenic	0.994
USH2A	O75445-1.3	K167Y	Pathogenic	0.988
USH2A	O75445-1.3	T168A	Neutral	0.025
USH2A	O75445-1.3	T168C	Neutral	0.131
USH2A	O75445-1.3	T168D	Neutral	0.17
USH2A	O75445-1.3	T168E	Neutral	0.109
USH2A	O75445-1.3	T168F	Neutral	0.143
USH2A	O75445-1.3	T168G	Neutral	0.074
USH2A	O75445-1.3	T168H	Neutral	0.125
USH2A	O75445-1.3	T168I	Neutral	0.095
USH2A	O75445-1.3	T168K	Neutral	0.06
USH2A	O75445-1.3	T168L	Neutral	0.091
USH2A	O75445-1.3	T168M	Neutral	0.073
USH2A	O75445-1.3	T168N	Neutral	0.074
USH2A	O75445-1.3	T168P	Neutral	0.131
USH2A	O75445-1.3	T168Q	Neutral	0.078
USH2A	O75445-1.3	T168R	Neutral	0.04
USH2A	O75445-1.3	T168S	Neutral	0.015
USH2A	O75445-1.3	T168V	Neutral	0.059
USH2A	O75445-1.3	T168W	Neutral	0.079
USH2A	O75445-1.3	T168Y	Neutral	0.084
USH2A	O75445-1.3	V169A	Neutral	0.02
USH2A	O75445-1.3	V169C	Neutral	0.057
USH2A	O75445-1.3	V169D	Neutral	0.467
USH2A	O75445-1.3	V169E	Neutral	0.331
USH2A	O75445-1.3	V169F	Neutral	0.047
USH2A	O75445-1.3	V169G	Neutral	0.131
USH2A	O75445-1.3	V169H	Neutral	0.366
USH2A	O75445-1.3	V169I	Neutral	0.003
USH2A	O75445-1.3	V169K	Neutral	0.204
USH2A	O75445-1.3	V169L	Neutral	0.013
USH2A	O75445-1.3	V169M	Neutral	0.01
USH2A	O75445-1.3	V169N	Neutral	0.486
USH2A	O75445-1.3	V169P	Neutral	0.151
USH2A	O75445-1.3	V169Q	Neutral	0.255
USH2A	O75445-1.3	V169R	Neutral	0.28
USH2A	O75445-1.3	V169S	Neutral	0.13
USH2A	O75445-1.3	V169T	Neutral	0.045
USH2A	O75445-1.3	V169W	Neutral	0.117
USH2A	O75445-1.3	V169Y	Neutral	0.034
USH2A	O75445-1.3	D170A	Pathogenic	0.565
USH2A	O75445-1.3	D170C	Pathogenic	0.884
USH2A	O75445-1.3	D170E	Neutral	0.035
USH2A	O75445-1.3	D170F	Pathogenic	0.765
USH2A	O75445-1.3	D170G	Neutral	0.21
USH2A	O75445-1.3	D170H	Neutral	0.322
USH2A	O75445-1.3	D170I	Pathogenic	0.824
USH2A	O75445-1.3	D170K	Neutral	0.164
USH2A	O75445-1.3	D170L	Pathogenic	0.91
USH2A	O75445-1.3	D170M	Pathogenic	0.779
USH2A	O75445-1.3	D170N	Neutral	0.114
USH2A	O75445-1.3	D170P	Pathogenic	0.594
USH2A	O75445-1.3	D170Q	Neutral	0.165
USH2A	O75445-1.3	D170R	Neutral	0.229
USH2A	O75445-1.3	D170S	Neutral	0.203
USH2A	O75445-1.3	D170T	Pathogenic	0.53
USH2A	O75445-1.3	D170V	Pathogenic	0.866
USH2A	O75445-1.3	D170W	Pathogenic	0.792
USH2A	O75445-1.3	D170Y	Pathogenic	0.641
USH2A	O75445-1.3	G171A	Neutral	0.128
USH2A	O75445-1.3	G171C	Pathogenic	0.57
USH2A	O75445-1.3	G171D	Neutral	0.163
USH2A	O75445-1.3	G171E	Neutral	0.19
USH2A	O75445-1.3	G171F	Neutral	0.291
USH2A	O75445-1.3	G171H	Neutral	0.12
USH2A	O75445-1.3	G171I	Pathogenic	0.574
USH2A	O75445-1.3	G171K	Neutral	0.108
USH2A	O75445-1.3	G171L	Pathogenic	0.561
USH2A	O75445-1.3	G171M	Neutral	0.307
USH2A	O75445-1.3	G171N	Neutral	0.063
USH2A	O75445-1.3	G171P	Neutral	0.31
USH2A	O75445-1.3	G171Q	Neutral	0.139
USH2A	O75445-1.3	G171R	Neutral	0.074
USH2A	O75445-1.3	G171S	Neutral	0.096
USH2A	O75445-1.3	G171T	Neutral	0.245
USH2A	O75445-1.3	G171V	Neutral	0.448
USH2A	O75445-1.3	G171W	Neutral	0.084
USH2A	O75445-1.3	G171Y	Neutral	0.183
USH2A	O75445-1.3	Q172A	Neutral	0.312
USH2A	O75445-1.3	Q172C	Pathogenic	0.859
USH2A	O75445-1.3	Q172D	Neutral	0.303
USH2A	O75445-1.3	Q172E	Neutral	0.122
USH2A	O75445-1.3	Q172F	Pathogenic	0.919
USH2A	O75445-1.3	Q172G	Neutral	0.326
USH2A	O75445-1.3	Q172H	Neutral	0.42
USH2A	O75445-1.3	Q172I	Pathogenic	0.942
USH2A	O75445-1.3	Q172K	Neutral	0.184
USH2A	O75445-1.3	Q172L	Pathogenic	0.872
USH2A	O75445-1.3	Q172M	Pathogenic	0.508
USH2A	O75445-1.3	Q172N	Neutral	0.319
USH2A	O75445-1.3	Q172P	Pathogenic	0.538
USH2A	O75445-1.3	Q172R	Neutral	0.13
USH2A	O75445-1.3	Q172S	Neutral	0.169
USH2A	O75445-1.3	Q172T	Pathogenic	0.505
USH2A	O75445-1.3	Q172V	Pathogenic	0.846
USH2A	O75445-1.3	Q172W	Pathogenic	0.718
USH2A	O75445-1.3	Q172Y	Pathogenic	0.544
USH2A	O75445-1.3	I173A	Neutral	0.177
USH2A	O75445-1.3	I173C	Neutral	0.221
USH2A	O75445-1.3	I173D	Pathogenic	0.806
USH2A	O75445-1.3	I173E	Pathogenic	0.874
USH2A	O75445-1.3	I173F	Neutral	0.165
USH2A	O75445-1.3	I173G	Pathogenic	0.619
USH2A	O75445-1.3	I173H	Pathogenic	0.863
USH2A	O75445-1.3	I173K	Pathogenic	0.904
USH2A	O75445-1.3	I173L	Neutral	0.054
USH2A	O75445-1.3	I173M	Neutral	0.14
USH2A	O75445-1.3	I173N	Pathogenic	0.818
USH2A	O75445-1.3	I173P	Pathogenic	0.657
USH2A	O75445-1.3	I173Q	Pathogenic	0.869
USH2A	O75445-1.3	I173R	Pathogenic	0.862
USH2A	O75445-1.3	I173S	Neutral	0.415
USH2A	O75445-1.3	I173T	Neutral	0.338
USH2A	O75445-1.3	I173V	Neutral	0.017
USH2A	O75445-1.3	I173W	Pathogenic	0.543
USH2A	O75445-1.3	I173Y	Neutral	0.36
USH2A	O75445-1.3	V174A	Neutral	0.275
USH2A	O75445-1.3	V174C	Pathogenic	0.533
USH2A	O75445-1.3	V174D	Pathogenic	0.943
USH2A	O75445-1.3	V174E	Pathogenic	0.904
USH2A	O75445-1.3	V174F	Neutral	0.487
USH2A	O75445-1.3	V174G	Pathogenic	0.741
USH2A	O75445-1.3	V174H	Pathogenic	0.917
USH2A	O75445-1.3	V174I	Neutral	0.048
USH2A	O75445-1.3	V174K	Pathogenic	0.83
USH2A	O75445-1.3	V174L	Neutral	0.199
USH2A	O75445-1.3	V174M	Neutral	0.164
USH2A	O75445-1.3	V174N	Pathogenic	0.947
USH2A	O75445-1.3	V174P	Pathogenic	0.772
USH2A	O75445-1.3	V174Q	Pathogenic	0.867
USH2A	O75445-1.3	V174R	Pathogenic	0.881
USH2A	O75445-1.3	V174S	Pathogenic	0.74
USH2A	O75445-1.3	V174T	Neutral	0.473
USH2A	O75445-1.3	V174W	Pathogenic	0.717
USH2A	O75445-1.3	V174Y	Neutral	0.401
USH2A	O75445-1.3	F175A	Pathogenic	0.908
USH2A	O75445-1.3	F175C	Pathogenic	0.928
USH2A	O75445-1.3	F175D	Pathogenic	0.988
USH2A	O75445-1.3	F175E	Pathogenic	0.993
USH2A	O75445-1.3	F175G	Pathogenic	0.934
USH2A	O75445-1.3	F175H	Pathogenic	0.96
USH2A	O75445-1.3	F175I	Pathogenic	0.85
USH2A	O75445-1.3	F175K	Pathogenic	0.997
USH2A	O75445-1.3	F175L	Pathogenic	0.855
USH2A	O75445-1.3	F175M	Pathogenic	0.881
USH2A	O75445-1.3	F175N	Pathogenic	0.989
USH2A	O75445-1.3	F175P	Pathogenic	0.989
USH2A	O75445-1.3	F175Q	Pathogenic	0.992
USH2A	O75445-1.3	F175R	Pathogenic	0.996
USH2A	O75445-1.3	F175S	Pathogenic	0.934
USH2A	O75445-1.3	F175T	Pathogenic	0.959
USH2A	O75445-1.3	F175V	Pathogenic	0.903
USH2A	O75445-1.3	F175W	Pathogenic	0.642
USH2A	O75445-1.3	F175Y	Neutral	0.456
USH2A	O75445-1.3	K176A	Neutral	0.367
USH2A	O75445-1.3	K176C	Pathogenic	0.886
USH2A	O75445-1.3	K176D	Neutral	0.423
USH2A	O75445-1.3	K176E	Neutral	0.211
USH2A	O75445-1.3	K176F	Pathogenic	0.982
USH2A	O75445-1.3	K176G	Neutral	0.381
USH2A	O75445-1.3	K176H	Pathogenic	0.732
USH2A	O75445-1.3	K176I	Pathogenic	0.975
USH2A	O75445-1.3	K176L	Pathogenic	0.943
USH2A	O75445-1.3	K176M	Pathogenic	0.851
USH2A	O75445-1.3	K176N	Neutral	0.291
USH2A	O75445-1.3	K176P	Pathogenic	0.598
USH2A	O75445-1.3	K176Q	Neutral	0.279
USH2A	O75445-1.3	K176R	Neutral	0.131
USH2A	O75445-1.3	K176S	Neutral	0.206
USH2A	O75445-1.3	K176T	Pathogenic	0.566
USH2A	O75445-1.3	K176V	Pathogenic	0.876
USH2A	O75445-1.3	K176W	Pathogenic	0.966
USH2A	O75445-1.3	K176Y	Pathogenic	0.931
USH2A	O75445-1.3	L177A	Pathogenic	0.615
USH2A	O75445-1.3	L177C	Pathogenic	0.678
USH2A	O75445-1.3	L177D	Pathogenic	0.986
USH2A	O75445-1.3	L177E	Pathogenic	0.981
USH2A	O75445-1.3	L177F	Pathogenic	0.616
USH2A	O75445-1.3	L177G	Pathogenic	0.923
USH2A	O75445-1.3	L177H	Pathogenic	0.979
USH2A	O75445-1.3	L177I	Neutral	0.306
USH2A	O75445-1.3	L177K	Pathogenic	0.968
USH2A	O75445-1.3	L177M	Neutral	0.346
USH2A	O75445-1.3	L177N	Pathogenic	0.971
USH2A	O75445-1.3	L177P	Pathogenic	0.934
USH2A	O75445-1.3	L177Q	Pathogenic	0.955
USH2A	O75445-1.3	L177R	Pathogenic	0.953
USH2A	O75445-1.3	L177S	Pathogenic	0.84
USH2A	O75445-1.3	L177T	Pathogenic	0.791
USH2A	O75445-1.3	L177V	Neutral	0.398
USH2A	O75445-1.3	L177W	Pathogenic	0.811
USH2A	O75445-1.3	L177Y	Pathogenic	0.807
USH2A	O75445-1.3	T178A	Pathogenic	0.566
USH2A	O75445-1.3	T178C	Pathogenic	0.885
USH2A	O75445-1.3	T178D	Pathogenic	0.913
USH2A	O75445-1.3	T178E	Pathogenic	0.862
USH2A	O75445-1.3	T178F	Pathogenic	0.895
USH2A	O75445-1.3	T178G	Pathogenic	0.804
USH2A	O75445-1.3	T178H	Pathogenic	0.879
USH2A	O75445-1.3	T178I	Pathogenic	0.842
USH2A	O75445-1.3	T178K	Pathogenic	0.764
USH2A	O75445-1.3	T178L	Pathogenic	0.835
USH2A	O75445-1.3	T178M	Pathogenic	0.801
USH2A	O75445-1.3	T178N	Pathogenic	0.803
USH2A	O75445-1.3	T178P	Pathogenic	0.885
USH2A	O75445-1.3	T178Q	Pathogenic	0.812
USH2A	O75445-1.3	T178R	Pathogenic	0.682
USH2A	O75445-1.3	T178S	Neutral	0.439
USH2A	O75445-1.3	T178V	Pathogenic	0.763
USH2A	O75445-1.3	T178W	Pathogenic	0.813
USH2A	O75445-1.3	T178Y	Pathogenic	0.823
USH2A	O75445-1.3	I179A	Neutral	0.325
USH2A	O75445-1.3	I179C	Neutral	0.389
USH2A	O75445-1.3	I179D	Pathogenic	0.903
USH2A	O75445-1.3	I179E	Pathogenic	0.939
USH2A	O75445-1.3	I179F	Neutral	0.307
USH2A	O75445-1.3	I179G	Pathogenic	0.784
USH2A	O75445-1.3	I179H	Pathogenic	0.934
USH2A	O75445-1.3	I179K	Pathogenic	0.955
USH2A	O75445-1.3	I179L	Neutral	0.112
USH2A	O75445-1.3	I179M	Neutral	0.267
USH2A	O75445-1.3	I179N	Pathogenic	0.909
USH2A	O75445-1.3	I179P	Pathogenic	0.811
USH2A	O75445-1.3	I179Q	Pathogenic	0.937
USH2A	O75445-1.3	I179R	Pathogenic	0.933
USH2A	O75445-1.3	I179S	Pathogenic	0.613
USH2A	O75445-1.3	I179T	Pathogenic	0.533
USH2A	O75445-1.3	I179V	Neutral	0.037
USH2A	O75445-1.3	I179W	Pathogenic	0.727
USH2A	O75445-1.3	I179Y	Pathogenic	0.558
USH2A	O75445-1.3	S180A	Pathogenic	0.79
USH2A	O75445-1.3	S180C	Pathogenic	0.956
USH2A	O75445-1.3	S180D	Pathogenic	0.876
USH2A	O75445-1.3	S180E	Pathogenic	0.788
USH2A	O75445-1.3	S180F	Pathogenic	0.939
USH2A	O75445-1.3	S180G	Pathogenic	0.8
USH2A	O75445-1.3	S180H	Pathogenic	0.837
USH2A	O75445-1.3	S180I	Pathogenic	0.957
USH2A	O75445-1.3	S180K	Pathogenic	0.658
USH2A	O75445-1.3	S180L	Pathogenic	0.955
USH2A	O75445-1.3	S180M	Pathogenic	0.88
USH2A	O75445-1.3	S180N	Pathogenic	0.709
USH2A	O75445-1.3	S180P	Pathogenic	0.944
USH2A	O75445-1.3	S180Q	Pathogenic	0.72
USH2A	O75445-1.3	S180R	Pathogenic	0.745
USH2A	O75445-1.3	S180T	Pathogenic	0.701
USH2A	O75445-1.3	S180V	Pathogenic	0.968
USH2A	O75445-1.3	S180W	Pathogenic	0.948
USH2A	O75445-1.3	S180Y	Pathogenic	0.894
USH2A	O75445-1.3	E181A	Pathogenic	0.685
USH2A	O75445-1.3	E181C	Pathogenic	0.985
USH2A	O75445-1.3	E181D	Neutral	0.209
USH2A	O75445-1.3	E181F	Pathogenic	0.975
USH2A	O75445-1.3	E181G	Pathogenic	0.699
USH2A	O75445-1.3	E181H	Pathogenic	0.716
USH2A	O75445-1.3	E181I	Pathogenic	0.983
USH2A	O75445-1.3	E181K	Neutral	0.342
USH2A	O75445-1.3	E181L	Pathogenic	0.982
USH2A	O75445-1.3	E181M	Pathogenic	0.949
USH2A	O75445-1.3	E181N	Pathogenic	0.606
USH2A	O75445-1.3	E181P	Pathogenic	0.848
USH2A	O75445-1.3	E181Q	Neutral	0.316
USH2A	O75445-1.3	E181R	Neutral	0.44
USH2A	O75445-1.3	E181S	Neutral	0.493
USH2A	O75445-1.3	E181T	Pathogenic	0.83
USH2A	O75445-1.3	E181V	Pathogenic	0.964
USH2A	O75445-1.3	E181W	Pathogenic	0.953
USH2A	O75445-1.3	E181Y	Pathogenic	0.905
USH2A	O75445-1.3	K182A	Neutral	0.231
USH2A	O75445-1.3	K182C	Pathogenic	0.802
USH2A	O75445-1.3	K182D	Neutral	0.276
USH2A	O75445-1.3	K182E	Neutral	0.122
USH2A	O75445-1.3	K182F	Pathogenic	0.967
USH2A	O75445-1.3	K182G	Neutral	0.243
USH2A	O75445-1.3	K182H	Pathogenic	0.587
USH2A	O75445-1.3	K182I	Pathogenic	0.954
USH2A	O75445-1.3	K182L	Pathogenic	0.895
USH2A	O75445-1.3	K182M	Pathogenic	0.748
USH2A	O75445-1.3	K182N	Neutral	0.176
USH2A	O75445-1.3	K182P	Neutral	0.436
USH2A	O75445-1.3	K182Q	Neutral	0.167
USH2A	O75445-1.3	K182R	Neutral	0.073
USH2A	O75445-1.3	K182S	Neutral	0.119
USH2A	O75445-1.3	K182T	Neutral	0.404
USH2A	O75445-1.3	K182V	Pathogenic	0.785
USH2A	O75445-1.3	K182W	Pathogenic	0.937
USH2A	O75445-1.3	K182Y	Pathogenic	0.874
USH2A	O75445-1.3	E183A	Neutral	0.355
USH2A	O75445-1.3	E183C	Pathogenic	0.944
USH2A	O75445-1.3	E183D	Neutral	0.062
USH2A	O75445-1.3	E183F	Pathogenic	0.909
USH2A	O75445-1.3	E183G	Neutral	0.369
USH2A	O75445-1.3	E183H	Neutral	0.389
USH2A	O75445-1.3	E183I	Pathogenic	0.935
USH2A	O75445-1.3	E183K	Neutral	0.116
USH2A	O75445-1.3	E183L	Pathogenic	0.932
USH2A	O75445-1.3	E183M	Pathogenic	0.825
USH2A	O75445-1.3	E183N	Neutral	0.28
USH2A	O75445-1.3	E183P	Pathogenic	0.585
USH2A	O75445-1.3	E183Q	Neutral	0.104
USH2A	O75445-1.3	E183R	Neutral	0.166
USH2A	O75445-1.3	E183S	Neutral	0.197
USH2A	O75445-1.3	E183T	Pathogenic	0.553
USH2A	O75445-1.3	E183V	Pathogenic	0.87
USH2A	O75445-1.3	E183W	Pathogenic	0.837
USH2A	O75445-1.3	E183Y	Pathogenic	0.705
USH2A	O75445-1.3	T184A	Neutral	0.185
USH2A	O75445-1.3	T184C	Pathogenic	0.572
USH2A	O75445-1.3	T184D	Pathogenic	0.645
USH2A	O75445-1.3	T184E	Pathogenic	0.521
USH2A	O75445-1.3	T184F	Pathogenic	0.596
USH2A	O75445-1.3	T184G	Neutral	0.416
USH2A	O75445-1.3	T184H	Pathogenic	0.559
USH2A	O75445-1.3	T184I	Neutral	0.481
USH2A	O75445-1.3	T184K	Neutral	0.36
USH2A	O75445-1.3	T184L	Neutral	0.469
USH2A	O75445-1.3	T184M	Neutral	0.411
USH2A	O75445-1.3	T184N	Neutral	0.415
USH2A	O75445-1.3	T184P	Pathogenic	0.571
USH2A	O75445-1.3	T184Q	Neutral	0.429
USH2A	O75445-1.3	T184R	Neutral	0.271
USH2A	O75445-1.3	T184S	Neutral	0.12
USH2A	O75445-1.3	T184V	Neutral	0.359
USH2A	O75445-1.3	T184W	Neutral	0.431
USH2A	O75445-1.3	T184Y	Neutral	0.447
USH2A	O75445-1.3	M185A	Neutral	0.301
USH2A	O75445-1.3	M185C	Neutral	0.362
USH2A	O75445-1.3	M185D	Pathogenic	0.892
USH2A	O75445-1.3	M185E	Pathogenic	0.858
USH2A	O75445-1.3	M185F	Neutral	0.408
USH2A	O75445-1.3	M185G	Pathogenic	0.587
USH2A	O75445-1.3	M185H	Pathogenic	0.847
USH2A	O75445-1.3	M185I	Neutral	0.302
USH2A	O75445-1.3	M185K	Pathogenic	0.782
USH2A	O75445-1.3	M185L	Neutral	0.153
USH2A	O75445-1.3	M185N	Pathogenic	0.797
USH2A	O75445-1.3	M185P	Pathogenic	0.627
USH2A	O75445-1.3	M185Q	Pathogenic	0.526
USH2A	O75445-1.3	M185R	Pathogenic	0.705
USH2A	O75445-1.3	M185S	Neutral	0.383
USH2A	O75445-1.3	M185T	Pathogenic	0.505
USH2A	O75445-1.3	M185V	Neutral	0.151
USH2A	O75445-1.3	M185W	Neutral	0.446
USH2A	O75445-1.3	M185Y	Pathogenic	0.53
USH2A	O75445-1.3	F186A	Pathogenic	0.803
USH2A	O75445-1.3	F186C	Pathogenic	0.843
USH2A	O75445-1.3	F186D	Pathogenic	0.972
USH2A	O75445-1.3	F186E	Pathogenic	0.983
USH2A	O75445-1.3	F186G	Pathogenic	0.855
USH2A	O75445-1.3	F186H	Pathogenic	0.909
USH2A	O75445-1.3	F186I	Pathogenic	0.702
USH2A	O75445-1.3	F186K	Pathogenic	0.994
USH2A	O75445-1.3	F186L	Pathogenic	0.71
USH2A	O75445-1.3	F186M	Pathogenic	0.755
USH2A	O75445-1.3	F186N	Pathogenic	0.974
USH2A	O75445-1.3	F186P	Pathogenic	0.973
USH2A	O75445-1.3	F186Q	Pathogenic	0.982
USH2A	O75445-1.3	F186R	Pathogenic	0.991
USH2A	O75445-1.3	F186S	Pathogenic	0.854
USH2A	O75445-1.3	F186T	Pathogenic	0.906
USH2A	O75445-1.3	F186V	Pathogenic	0.794
USH2A	O75445-1.3	F186W	Neutral	0.427
USH2A	O75445-1.3	F186Y	Neutral	0.258
USH2A	O75445-1.3	Y187A	Neutral	0.422
USH2A	O75445-1.3	Y187C	Neutral	0.495
USH2A	O75445-1.3	Y187D	Pathogenic	0.86
USH2A	O75445-1.3	Y187E	Pathogenic	0.818
USH2A	O75445-1.3	Y187F	Neutral	0.102
USH2A	O75445-1.3	Y187G	Pathogenic	0.513
USH2A	O75445-1.3	Y187H	Neutral	0.131
USH2A	O75445-1.3	Y187I	Pathogenic	0.687
USH2A	O75445-1.3	Y187K	Pathogenic	0.925
USH2A	O75445-1.3	Y187L	Pathogenic	0.676
USH2A	O75445-1.3	Y187M	Pathogenic	0.622
USH2A	O75445-1.3	Y187N	Pathogenic	0.744
USH2A	O75445-1.3	Y187P	Pathogenic	0.74
USH2A	O75445-1.3	Y187Q	Pathogenic	0.653
USH2A	O75445-1.3	Y187R	Pathogenic	0.923
USH2A	O75445-1.3	Y187S	Pathogenic	0.512
USH2A	O75445-1.3	Y187T	Pathogenic	0.633
USH2A	O75445-1.3	Y187V	Neutral	0.471
USH2A	O75445-1.3	Y187W	Neutral	0.164
USH2A	O75445-1.3	Y188A	Pathogenic	0.894
USH2A	O75445-1.3	Y188C	Pathogenic	0.919
USH2A	O75445-1.3	Y188D	Pathogenic	0.986
USH2A	O75445-1.3	Y188E	Pathogenic	0.981
USH2A	O75445-1.3	Y188F	Pathogenic	0.567
USH2A	O75445-1.3	Y188G	Pathogenic	0.924
USH2A	O75445-1.3	Y188H	Pathogenic	0.634
USH2A	O75445-1.3	Y188I	Pathogenic	0.962
USH2A	O75445-1.3	Y188K	Pathogenic	0.993
USH2A	O75445-1.3	Y188L	Pathogenic	0.96
USH2A	O75445-1.3	Y188M	Pathogenic	0.95
USH2A	O75445-1.3	Y188N	Pathogenic	0.971
USH2A	O75445-1.3	Y188P	Pathogenic	0.97
USH2A	O75445-1.3	Y188Q	Pathogenic	0.956
USH2A	O75445-1.3	Y188R	Pathogenic	0.993
USH2A	O75445-1.3	Y188S	Pathogenic	0.924
USH2A	O75445-1.3	Y188T	Pathogenic	0.952
USH2A	O75445-1.3	Y188V	Pathogenic	0.911
USH2A	O75445-1.3	Y188W	Pathogenic	0.692
USH2A	O75445-1.3	R189A	Neutral	0.316
USH2A	O75445-1.3	R189C	Pathogenic	0.861
USH2A	O75445-1.3	R189D	Pathogenic	0.571
USH2A	O75445-1.3	R189E	Neutral	0.327
USH2A	O75445-1.3	R189F	Pathogenic	0.978
USH2A	O75445-1.3	R189G	Neutral	0.329
USH2A	O75445-1.3	R189H	Neutral	0.488
USH2A	O75445-1.3	R189I	Pathogenic	0.969
USH2A	O75445-1.3	R189K	Neutral	0.153
USH2A	O75445-1.3	R189L	Pathogenic	0.929
USH2A	O75445-1.3	R189M	Pathogenic	0.82
USH2A	O75445-1.3	R189N	Neutral	0.246
USH2A	O75445-1.3	R189P	Pathogenic	0.73
USH2A	O75445-1.3	R189Q	Neutral	0.235
USH2A	O75445-1.3	R189S	Neutral	0.32
USH2A	O75445-1.3	R189T	Pathogenic	0.509
USH2A	O75445-1.3	R189V	Pathogenic	0.928
USH2A	O75445-1.3	R189W	Pathogenic	0.981
USH2A	O75445-1.3	R189Y	Pathogenic	0.94
USH2A	O75445-1.3	T190A	Neutral	0.299
USH2A	O75445-1.3	T190C	Pathogenic	0.714
USH2A	O75445-1.3	T190D	Pathogenic	0.773
USH2A	O75445-1.3	T190E	Pathogenic	0.671
USH2A	O75445-1.3	T190F	Pathogenic	0.735
USH2A	O75445-1.3	T190G	Pathogenic	0.572
USH2A	O75445-1.3	T190H	Pathogenic	0.704
USH2A	O75445-1.3	T190I	Pathogenic	0.635
USH2A	O75445-1.3	T190K	Pathogenic	0.513
USH2A	O75445-1.3	T190L	Pathogenic	0.623
USH2A	O75445-1.3	T190M	Pathogenic	0.567
USH2A	O75445-1.3	T190N	Pathogenic	0.571
USH2A	O75445-1.3	T190P	Pathogenic	0.714
USH2A	O75445-1.3	T190Q	Pathogenic	0.585
USH2A	O75445-1.3	T190R	Neutral	0.411
USH2A	O75445-1.3	T190S	Neutral	0.203
USH2A	O75445-1.3	T190V	Pathogenic	0.512
USH2A	O75445-1.3	T190W	Pathogenic	0.586
USH2A	O75445-1.3	T190Y	Pathogenic	0.602
USH2A	O75445-1.3	V191A	Neutral	0.111
USH2A	O75445-1.3	V191C	Neutral	0.273
USH2A	O75445-1.3	V191D	Pathogenic	0.846
USH2A	O75445-1.3	V191E	Pathogenic	0.756
USH2A	O75445-1.3	V191F	Neutral	0.237
USH2A	O75445-1.3	V191G	Neutral	0.484
USH2A	O75445-1.3	V191H	Pathogenic	0.783
USH2A	O75445-1.3	V191I	Neutral	0.016
USH2A	O75445-1.3	V191K	Pathogenic	0.616
USH2A	O75445-1.3	V191L	Neutral	0.075
USH2A	O75445-1.3	V191M	Neutral	0.061
USH2A	O75445-1.3	V191N	Pathogenic	0.855
USH2A	O75445-1.3	V191P	Pathogenic	0.526
USH2A	O75445-1.3	V191Q	Pathogenic	0.682
USH2A	O75445-1.3	V191R	Pathogenic	0.708
USH2A	O75445-1.3	V191S	Neutral	0.483
USH2A	O75445-1.3	V191T	Neutral	0.228
USH2A	O75445-1.3	V191W	Neutral	0.454
USH2A	O75445-1.3	V191Y	Neutral	0.18
USH2A	O75445-1.3	N192A	Pathogenic	0.773
USH2A	O75445-1.3	N192C	Pathogenic	0.952
USH2A	O75445-1.3	N192D	Neutral	0.3
USH2A	O75445-1.3	N192E	Neutral	0.415
USH2A	O75445-1.3	N192F	Pathogenic	0.922
USH2A	O75445-1.3	N192G	Neutral	0.233
USH2A	O75445-1.3	N192H	Neutral	0.247
USH2A	O75445-1.3	N192I	Pathogenic	0.944
USH2A	O75445-1.3	N192K	Neutral	0.268
USH2A	O75445-1.3	N192L	Pathogenic	0.941
USH2A	O75445-1.3	N192M	Pathogenic	0.848
USH2A	O75445-1.3	N192P	Pathogenic	0.897
USH2A	O75445-1.3	N192Q	Neutral	0.417
USH2A	O75445-1.3	N192R	Neutral	0.195
USH2A	O75445-1.3	N192S	Neutral	0.226
USH2A	O75445-1.3	N192T	Pathogenic	0.595
USH2A	O75445-1.3	N192V	Pathogenic	0.959
USH2A	O75445-1.3	N192W	Pathogenic	0.932
USH2A	O75445-1.3	N192Y	Pathogenic	0.738
USH2A	O75445-1.3	G193A	Neutral	0.487
USH2A	O75445-1.3	G193C	Pathogenic	0.896
USH2A	O75445-1.3	G193D	Pathogenic	0.558
USH2A	O75445-1.3	G193E	Pathogenic	0.602
USH2A	O75445-1.3	G193F	Pathogenic	0.726
USH2A	O75445-1.3	G193H	Neutral	0.468
USH2A	O75445-1.3	G193I	Pathogenic	0.897
USH2A	O75445-1.3	G193K	Neutral	0.439
USH2A	O75445-1.3	G193L	Pathogenic	0.892
USH2A	O75445-1.3	G193M	Pathogenic	0.741
USH2A	O75445-1.3	G193N	Neutral	0.302
USH2A	O75445-1.3	G193P	Pathogenic	0.743
USH2A	O75445-1.3	G193Q	Pathogenic	0.511
USH2A	O75445-1.3	G193R	Neutral	0.342
USH2A	O75445-1.3	G193S	Neutral	0.406
USH2A	O75445-1.3	G193T	Pathogenic	0.677
USH2A	O75445-1.3	G193V	Pathogenic	0.84
USH2A	O75445-1.3	G193W	Neutral	0.373
USH2A	O75445-1.3	G193Y	Pathogenic	0.592
USH2A	O75445-1.3	L194A	Neutral	0.214
USH2A	O75445-1.3	L194C	Neutral	0.264
USH2A	O75445-1.3	L194D	Pathogenic	0.923
USH2A	O75445-1.3	L194E	Pathogenic	0.898
USH2A	O75445-1.3	L194F	Neutral	0.215
USH2A	O75445-1.3	L194G	Pathogenic	0.673
USH2A	O75445-1.3	L194H	Pathogenic	0.889
USH2A	O75445-1.3	L194I	Neutral	0.07
USH2A	O75445-1.3	L194K	Pathogenic	0.839
USH2A	O75445-1.3	L194M	Neutral	0.083
USH2A	O75445-1.3	L194N	Pathogenic	0.85
USH2A	O75445-1.3	L194P	Pathogenic	0.708
USH2A	O75445-1.3	L194Q	Pathogenic	0.786
USH2A	O75445-1.3	L194R	Pathogenic	0.775
USH2A	O75445-1.3	L194S	Neutral	0.473
USH2A	O75445-1.3	L194T	Neutral	0.392
USH2A	O75445-1.3	L194V	Neutral	0.101
USH2A	O75445-1.3	L194W	Neutral	0.422
USH2A	O75445-1.3	L194Y	Neutral	0.416
USH2A	O75445-1.3	Q195A	Pathogenic	0.511
USH2A	O75445-1.3	Q195C	Pathogenic	0.933
USH2A	O75445-1.3	Q195D	Pathogenic	0.5
USH2A	O75445-1.3	Q195E	Neutral	0.243
USH2A	O75445-1.3	Q195F	Pathogenic	0.963
USH2A	O75445-1.3	Q195G	Pathogenic	0.527
USH2A	O75445-1.3	Q195H	Pathogenic	0.625
USH2A	O75445-1.3	Q195I	Pathogenic	0.974
USH2A	O75445-1.3	Q195K	Neutral	0.343
USH2A	O75445-1.3	Q195L	Pathogenic	0.94
USH2A	O75445-1.3	Q195M	Pathogenic	0.704
USH2A	O75445-1.3	Q195N	Pathogenic	0.519
USH2A	O75445-1.3	Q195P	Pathogenic	0.729
USH2A	O75445-1.3	Q195R	Neutral	0.257
USH2A	O75445-1.3	Q195S	Neutral	0.319
USH2A	O75445-1.3	Q195T	Pathogenic	0.701
USH2A	O75445-1.3	Q195V	Pathogenic	0.927
USH2A	O75445-1.3	Q195W	Pathogenic	0.855
USH2A	O75445-1.3	Q195Y	Pathogenic	0.733
USH2A	O75445-1.3	P196A	Neutral	0.28
USH2A	O75445-1.3	P196C	Pathogenic	0.776
USH2A	O75445-1.3	P196D	Pathogenic	0.573
USH2A	O75445-1.3	P196E	Neutral	0.414
USH2A	O75445-1.3	P196F	Pathogenic	0.76
USH2A	O75445-1.3	P196G	Neutral	0.359
USH2A	O75445-1.3	P196H	Neutral	0.452
USH2A	O75445-1.3	P196I	Pathogenic	0.665
USH2A	O75445-1.3	P196K	Neutral	0.267
USH2A	O75445-1.3	P196L	Pathogenic	0.654
USH2A	O75445-1.3	P196M	Neutral	0.396
USH2A	O75445-1.3	P196N	Pathogenic	0.706
USH2A	O75445-1.3	P196Q	Neutral	0.328
USH2A	O75445-1.3	P196R	Neutral	0.356
USH2A	O75445-1.3	P196S	Neutral	0.358
USH2A	O75445-1.3	P196T	Neutral	0.431
USH2A	O75445-1.3	P196V	Pathogenic	0.545
USH2A	O75445-1.3	P196W	Pathogenic	0.618
USH2A	O75445-1.3	P196Y	Neutral	0.431
USH2A	O75445-1.3	P197A	Neutral	0.392
USH2A	O75445-1.3	P197C	Pathogenic	0.852
USH2A	O75445-1.3	P197D	Pathogenic	0.691
USH2A	O75445-1.3	P197E	Pathogenic	0.54
USH2A	O75445-1.3	P197F	Pathogenic	0.84
USH2A	O75445-1.3	P197G	Neutral	0.483
USH2A	O75445-1.3	P197H	Pathogenic	0.578
USH2A	O75445-1.3	P197I	Pathogenic	0.768
USH2A	O75445-1.3	P197K	Neutral	0.378
USH2A	O75445-1.3	P197L	Pathogenic	0.758
USH2A	O75445-1.3	P197M	Pathogenic	0.521
USH2A	O75445-1.3	P197N	Pathogenic	0.8
USH2A	O75445-1.3	P197Q	Neutral	0.448
USH2A	O75445-1.3	P197R	Neutral	0.479
USH2A	O75445-1.3	P197S	Neutral	0.481
USH2A	O75445-1.3	P197T	Pathogenic	0.557
USH2A	O75445-1.3	P197V	Pathogenic	0.666
USH2A	O75445-1.3	P197W	Pathogenic	0.729
USH2A	O75445-1.3	P197Y	Pathogenic	0.557
USH2A	O75445-1.3	I198A	Pathogenic	0.575
USH2A	O75445-1.3	I198C	Pathogenic	0.641
USH2A	O75445-1.3	I198D	Pathogenic	0.963
USH2A	O75445-1.3	I198E	Pathogenic	0.978
USH2A	O75445-1.3	I198F	Pathogenic	0.554
USH2A	O75445-1.3	I198G	Pathogenic	0.911
USH2A	O75445-1.3	I198H	Pathogenic	0.975
USH2A	O75445-1.3	I198K	Pathogenic	0.983
USH2A	O75445-1.3	I198L	Neutral	0.262
USH2A	O75445-1.3	I198M	Pathogenic	0.506
USH2A	O75445-1.3	I198N	Pathogenic	0.966
USH2A	O75445-1.3	I198P	Pathogenic	0.923
USH2A	O75445-1.3	I198Q	Pathogenic	0.976
USH2A	O75445-1.3	I198R	Pathogenic	0.975
USH2A	O75445-1.3	I198S	Pathogenic	0.816
USH2A	O75445-1.3	I198T	Pathogenic	0.762
USH2A	O75445-1.3	I198V	Neutral	0.097
USH2A	O75445-1.3	I198W	Pathogenic	0.882
USH2A	O75445-1.3	I198Y	Pathogenic	0.78
USH2A	O75445-1.3	K199A	Neutral	0.423
USH2A	O75445-1.3	K199C	Pathogenic	0.908
USH2A	O75445-1.3	K199D	Neutral	0.482
USH2A	O75445-1.3	K199E	Neutral	0.253
USH2A	O75445-1.3	K199F	Pathogenic	0.986
USH2A	O75445-1.3	K199G	Neutral	0.439
USH2A	O75445-1.3	K199H	Pathogenic	0.776
USH2A	O75445-1.3	K199I	Pathogenic	0.98
USH2A	O75445-1.3	K199L	Pathogenic	0.954
USH2A	O75445-1.3	K199M	Pathogenic	0.879
USH2A	O75445-1.3	K199N	Neutral	0.342
USH2A	O75445-1.3	K199P	Pathogenic	0.653
USH2A	O75445-1.3	K199Q	Neutral	0.329
USH2A	O75445-1.3	K199R	Neutral	0.16
USH2A	O75445-1.3	K199S	Neutral	0.247
USH2A	O75445-1.3	K199T	Pathogenic	0.623
USH2A	O75445-1.3	K199V	Pathogenic	0.899
USH2A	O75445-1.3	K199W	Pathogenic	0.973
USH2A	O75445-1.3	K199Y	Pathogenic	0.944
USH2A	O75445-1.3	V200A	Neutral	0.18
USH2A	O75445-1.3	V200C	Neutral	0.398
USH2A	O75445-1.3	V200D	Pathogenic	0.906
USH2A	O75445-1.3	V200E	Pathogenic	0.845
USH2A	O75445-1.3	V200F	Neutral	0.355
USH2A	O75445-1.3	V200G	Pathogenic	0.624
USH2A	O75445-1.3	V200H	Pathogenic	0.865
USH2A	O75445-1.3	V200I	Neutral	0.028
USH2A	O75445-1.3	V200K	Pathogenic	0.739
USH2A	O75445-1.3	V200L	Neutral	0.126
USH2A	O75445-1.3	V200M	Neutral	0.102
USH2A	O75445-1.3	V200N	Pathogenic	0.913
USH2A	O75445-1.3	V200P	Pathogenic	0.662
USH2A	O75445-1.3	V200Q	Pathogenic	0.791
USH2A	O75445-1.3	V200R	Pathogenic	0.811
USH2A	O75445-1.3	V200S	Pathogenic	0.623
USH2A	O75445-1.3	V200T	Neutral	0.342
USH2A	O75445-1.3	V200W	Pathogenic	0.595
USH2A	O75445-1.3	V200Y	Neutral	0.279
USH2A	O75445-1.3	M201A	Pathogenic	0.597
USH2A	O75445-1.3	M201C	Pathogenic	0.661
USH2A	O75445-1.3	M201D	Pathogenic	0.966
USH2A	O75445-1.3	M201E	Pathogenic	0.954
USH2A	O75445-1.3	M201F	Pathogenic	0.703
USH2A	O75445-1.3	M201G	Pathogenic	0.83
USH2A	O75445-1.3	M201H	Pathogenic	0.95
USH2A	O75445-1.3	M201I	Pathogenic	0.598
USH2A	O75445-1.3	M201K	Pathogenic	0.925
USH2A	O75445-1.3	M201L	Neutral	0.382
USH2A	O75445-1.3	M201N	Pathogenic	0.931
USH2A	O75445-1.3	M201P	Pathogenic	0.852
USH2A	O75445-1.3	M201Q	Pathogenic	0.792
USH2A	O75445-1.3	M201R	Pathogenic	0.891
USH2A	O75445-1.3	M201S	Pathogenic	0.681
USH2A	O75445-1.3	M201T	Pathogenic	0.778
USH2A	O75445-1.3	M201V	Neutral	0.38
USH2A	O75445-1.3	M201W	Pathogenic	0.735
USH2A	O75445-1.3	M201Y	Pathogenic	0.795
USH2A	O75445-1.3	T202A	Pathogenic	0.707
USH2A	O75445-1.3	T202C	Pathogenic	0.934
USH2A	O75445-1.3	T202D	Pathogenic	0.951
USH2A	O75445-1.3	T202E	Pathogenic	0.92
USH2A	O75445-1.3	T202F	Pathogenic	0.94
USH2A	O75445-1.3	T202G	Pathogenic	0.883
USH2A	O75445-1.3	T202H	Pathogenic	0.931
USH2A	O75445-1.3	T202I	Pathogenic	0.908
USH2A	O75445-1.3	T202K	Pathogenic	0.856
USH2A	O75445-1.3	T202L	Pathogenic	0.904
USH2A	O75445-1.3	T202M	Pathogenic	0.881
USH2A	O75445-1.3	T202N	Pathogenic	0.883
USH2A	O75445-1.3	T202P	Pathogenic	0.934
USH2A	O75445-1.3	T202Q	Pathogenic	0.889
USH2A	O75445-1.3	T202R	Pathogenic	0.798
USH2A	O75445-1.3	T202S	Pathogenic	0.591
USH2A	O75445-1.3	T202V	Pathogenic	0.856
USH2A	O75445-1.3	T202W	Pathogenic	0.889
USH2A	O75445-1.3	T202Y	Pathogenic	0.896
USH2A	O75445-1.3	L203A	Neutral	0.128
USH2A	O75445-1.3	L203C	Neutral	0.162
USH2A	O75445-1.3	L203D	Pathogenic	0.866
USH2A	O75445-1.3	L203E	Pathogenic	0.825
USH2A	O75445-1.3	L203F	Neutral	0.128
USH2A	O75445-1.3	L203G	Pathogenic	0.525
USH2A	O75445-1.3	L203H	Pathogenic	0.811
USH2A	O75445-1.3	L203I	Neutral	0.039
USH2A	O75445-1.3	L203K	Pathogenic	0.737
USH2A	O75445-1.3	L203M	Neutral	0.046
USH2A	O75445-1.3	L203N	Pathogenic	0.753
USH2A	O75445-1.3	L203P	Pathogenic	0.567
USH2A	O75445-1.3	L203Q	Pathogenic	0.664
USH2A	O75445-1.3	L203R	Pathogenic	0.65
USH2A	O75445-1.3	L203S	Neutral	0.326
USH2A	O75445-1.3	L203T	Neutral	0.258
USH2A	O75445-1.3	L203V	Neutral	0.057
USH2A	O75445-1.3	L203W	Neutral	0.282
USH2A	O75445-1.3	L203Y	Neutral	0.277
USH2A	O75445-1.3	G204A	Pathogenic	0.647
USH2A	O75445-1.3	G204C	Pathogenic	0.943
USH2A	O75445-1.3	G204D	Pathogenic	0.709
USH2A	O75445-1.3	G204E	Pathogenic	0.745
USH2A	O75445-1.3	G204F	Pathogenic	0.837
USH2A	O75445-1.3	G204H	Pathogenic	0.63
USH2A	O75445-1.3	G204I	Pathogenic	0.944
USH2A	O75445-1.3	G204K	Pathogenic	0.602
USH2A	O75445-1.3	G204L	Pathogenic	0.941
USH2A	O75445-1.3	G204M	Pathogenic	0.847
USH2A	O75445-1.3	G204N	Neutral	0.456
USH2A	O75445-1.3	G204P	Pathogenic	0.849
USH2A	O75445-1.3	G204Q	Pathogenic	0.669
USH2A	O75445-1.3	G204R	Pathogenic	0.501
USH2A	O75445-1.3	G204S	Pathogenic	0.57
USH2A	O75445-1.3	G204T	Pathogenic	0.802
USH2A	O75445-1.3	G204V	Pathogenic	0.91
USH2A	O75445-1.3	G204W	Pathogenic	0.535
USH2A	O75445-1.3	G204Y	Pathogenic	0.737
USH2A	O75445-1.3	R205A	Pathogenic	0.616
USH2A	O75445-1.3	R205C	Pathogenic	0.956
USH2A	O75445-1.3	R205D	Pathogenic	0.823
USH2A	O75445-1.3	R205E	Pathogenic	0.629
USH2A	O75445-1.3	R205F	Pathogenic	0.994
USH2A	O75445-1.3	R205G	Pathogenic	0.631
USH2A	O75445-1.3	R205H	Pathogenic	0.768
USH2A	O75445-1.3	R205I	Pathogenic	0.991
USH2A	O75445-1.3	R205K	Neutral	0.386
USH2A	O75445-1.3	R205L	Pathogenic	0.979
USH2A	O75445-1.3	R205M	Pathogenic	0.941
USH2A	O75445-1.3	R205N	Pathogenic	0.532
USH2A	O75445-1.3	R205P	Pathogenic	0.904
USH2A	O75445-1.3	R205Q	Pathogenic	0.517
USH2A	O75445-1.3	R205S	Pathogenic	0.621
USH2A	O75445-1.3	R205T	Pathogenic	0.783
USH2A	O75445-1.3	R205V	Pathogenic	0.978
USH2A	O75445-1.3	R205W	Pathogenic	0.995
USH2A	O75445-1.3	R205Y	Pathogenic	0.982
USH2A	O75445-1.3	I206A	Pathogenic	0.549
USH2A	O75445-1.3	I206C	Pathogenic	0.616
USH2A	O75445-1.3	I206D	Pathogenic	0.959
USH2A	O75445-1.3	I206E	Pathogenic	0.975
USH2A	O75445-1.3	I206F	Pathogenic	0.528
USH2A	O75445-1.3	I206G	Pathogenic	0.902
USH2A	O75445-1.3	I206H	Pathogenic	0.973
USH2A	O75445-1.3	I206K	Pathogenic	0.981
USH2A	O75445-1.3	I206L	Neutral	0.242
USH2A	O75445-1.3	I206M	Neutral	0.479
USH2A	O75445-1.3	I206N	Pathogenic	0.962
USH2A	O75445-1.3	I206P	Pathogenic	0.915
USH2A	O75445-1.3	I206Q	Pathogenic	0.974
USH2A	O75445-1.3	I206R	Pathogenic	0.972
USH2A	O75445-1.3	I206S	Pathogenic	0.8
USH2A	O75445-1.3	I206T	Pathogenic	0.742
USH2A	O75445-1.3	I206V	Neutral	0.088
USH2A	O75445-1.3	I206W	Pathogenic	0.87
USH2A	O75445-1.3	I206Y	Pathogenic	0.761
USH2A	O75445-1.3	L207A	Neutral	0.163
USH2A	O75445-1.3	L207C	Neutral	0.204
USH2A	O75445-1.3	L207D	Pathogenic	0.896
USH2A	O75445-1.3	L207E	Pathogenic	0.862
USH2A	O75445-1.3	L207F	Neutral	0.164
USH2A	O75445-1.3	L207G	Pathogenic	0.595
USH2A	O75445-1.3	L207H	Pathogenic	0.851
USH2A	O75445-1.3	L207I	Neutral	0.051
USH2A	O75445-1.3	L207K	Pathogenic	0.788
USH2A	O75445-1.3	L207M	Neutral	0.061
USH2A	O75445-1.3	L207N	Pathogenic	0.802
USH2A	O75445-1.3	L207P	Pathogenic	0.635
USH2A	O75445-1.3	L207Q	Pathogenic	0.724
USH2A	O75445-1.3	L207R	Pathogenic	0.712
USH2A	O75445-1.3	L207S	Neutral	0.391
USH2A	O75445-1.3	L207T	Neutral	0.316
USH2A	O75445-1.3	L207V	Neutral	0.075
USH2A	O75445-1.3	L207W	Neutral	0.343
USH2A	O75445-1.3	L207Y	Neutral	0.338
USH2A	O75445-1.3	V208A	Neutral	0.171
USH2A	O75445-1.3	V208C	Neutral	0.382
USH2A	O75445-1.3	V208D	Pathogenic	0.9
USH2A	O75445-1.3	V208E	Pathogenic	0.836
USH2A	O75445-1.3	V208F	Neutral	0.339
USH2A	O75445-1.3	V208G	Pathogenic	0.608
USH2A	O75445-1.3	V208H	Pathogenic	0.857
USH2A	O75445-1.3	V208I	Neutral	0.026
USH2A	O75445-1.3	V208K	Pathogenic	0.726
USH2A	O75445-1.3	V208L	Neutral	0.118
USH2A	O75445-1.3	V208M	Neutral	0.096
USH2A	O75445-1.3	V208N	Pathogenic	0.907
USH2A	O75445-1.3	V208P	Pathogenic	0.647
USH2A	O75445-1.3	V208Q	Pathogenic	0.78
USH2A	O75445-1.3	V208R	Pathogenic	0.8
USH2A	O75445-1.3	V208S	Pathogenic	0.607
USH2A	O75445-1.3	V208T	Neutral	0.327
USH2A	O75445-1.3	V208W	Pathogenic	0.578
USH2A	O75445-1.3	V208Y	Neutral	0.266
USH2A	O75445-1.3	K209A	Neutral	0.247
USH2A	O75445-1.3	K209C	Pathogenic	0.815
USH2A	O75445-1.3	K209D	Neutral	0.293
USH2A	O75445-1.3	K209E	Neutral	0.131
USH2A	O75445-1.3	K209F	Pathogenic	0.969
USH2A	O75445-1.3	K209G	Neutral	0.258
USH2A	O75445-1.3	K209H	Pathogenic	0.607
USH2A	O75445-1.3	K209I	Pathogenic	0.957
USH2A	O75445-1.3	K209L	Pathogenic	0.903
USH2A	O75445-1.3	K209M	Pathogenic	0.764
USH2A	O75445-1.3	K209N	Neutral	0.188
USH2A	O75445-1.3	K209P	Neutral	0.456
USH2A	O75445-1.3	K209Q	Neutral	0.179
USH2A	O75445-1.3	K209R	Neutral	0.078
USH2A	O75445-1.3	K209S	Neutral	0.128
USH2A	O75445-1.3	K209T	Neutral	0.424
USH2A	O75445-1.3	K209V	Pathogenic	0.799
USH2A	O75445-1.3	K209W	Pathogenic	0.942
USH2A	O75445-1.3	K209Y	Pathogenic	0.883
USH2A	O75445-1.3	K210A	Neutral	0.288
USH2A	O75445-1.3	K210C	Pathogenic	0.845
USH2A	O75445-1.3	K210D	Neutral	0.339
USH2A	O75445-1.3	K210E	Neutral	0.158
USH2A	O75445-1.3	K210F	Pathogenic	0.975
USH2A	O75445-1.3	K210G	Neutral	0.301
USH2A	O75445-1.3	K210H	Pathogenic	0.656
USH2A	O75445-1.3	K210I	Pathogenic	0.965
USH2A	O75445-1.3	K210L	Pathogenic	0.92
USH2A	O75445-1.3	K210M	Pathogenic	0.8
USH2A	O75445-1.3	K210N	Neutral	0.223
USH2A	O75445-1.3	K210P	Pathogenic	0.51
USH2A	O75445-1.3	K210Q	Neutral	0.213
USH2A	O75445-1.3	K210R	Neutral	0.095
USH2A	O75445-1.3	K210S	Neutral	0.154
USH2A	O75445-1.3	K210T	Neutral	0.477
USH2A	O75445-1.3	K210V	Pathogenic	0.831
USH2A	O75445-1.3	K210W	Pathogenic	0.952
USH2A	O75445-1.3	K210Y	Pathogenic	0.904
USH2A	O75445-1.3	W211A	Pathogenic	0.989
USH2A	O75445-1.3	W211C	Pathogenic	0.982
USH2A	O75445-1.3	W211D	Pathogenic	0.999
USH2A	O75445-1.3	W211E	Pathogenic	0.998
USH2A	O75445-1.3	W211F	Pathogenic	0.936
USH2A	O75445-1.3	W211G	Pathogenic	0.963
USH2A	O75445-1.3	W211H	Pathogenic	0.996
USH2A	O75445-1.3	W211I	Pathogenic	0.996
USH2A	O75445-1.3	W211K	Pathogenic	0.999
USH2A	O75445-1.3	W211L	Pathogenic	0.992
USH2A	O75445-1.3	W211M	Pathogenic	0.986
USH2A	O75445-1.3	W211N	Pathogenic	0.999
USH2A	O75445-1.3	W211P	Pathogenic	0.997
USH2A	O75445-1.3	W211Q	Pathogenic	0.996
USH2A	O75445-1.3	W211R	Pathogenic	1.0
USH2A	O75445-1.3	W211S	Pathogenic	0.993
USH2A	O75445-1.3	W211T	Pathogenic	0.99
USH2A	O75445-1.3	W211V	Pathogenic	0.995
USH2A	O75445-1.3	W211Y	Pathogenic	0.922
USH2A	O75445-1.3	I212A	Neutral	0.355
USH2A	O75445-1.3	I212C	Neutral	0.42
USH2A	O75445-1.3	I212D	Pathogenic	0.914
USH2A	O75445-1.3	I212E	Pathogenic	0.946
USH2A	O75445-1.3	I212F	Neutral	0.336
USH2A	O75445-1.3	I212G	Pathogenic	0.806
USH2A	O75445-1.3	I212H	Pathogenic	0.941
USH2A	O75445-1.3	I212K	Pathogenic	0.96
USH2A	O75445-1.3	I212L	Neutral	0.126
USH2A	O75445-1.3	I212M	Neutral	0.293
USH2A	O75445-1.3	I212N	Pathogenic	0.92
USH2A	O75445-1.3	I212P	Pathogenic	0.83
USH2A	O75445-1.3	I212Q	Pathogenic	0.944
USH2A	O75445-1.3	I212R	Pathogenic	0.941
USH2A	O75445-1.3	I212S	Pathogenic	0.644
USH2A	O75445-1.3	I212T	Pathogenic	0.565
USH2A	O75445-1.3	I212V	Neutral	0.042
USH2A	O75445-1.3	I212W	Pathogenic	0.752
USH2A	O75445-1.3	I212Y	Pathogenic	0.589
USH2A	O75445-1.3	H213A	Pathogenic	0.965
USH2A	O75445-1.3	H213C	Pathogenic	0.994
USH2A	O75445-1.3	H213D	Pathogenic	0.974
USH2A	O75445-1.3	H213E	Pathogenic	0.965
USH2A	O75445-1.3	H213F	Pathogenic	0.987
USH2A	O75445-1.3	H213G	Pathogenic	0.937
USH2A	O75445-1.3	H213I	Pathogenic	0.998
USH2A	O75445-1.3	H213K	Pathogenic	0.983
USH2A	O75445-1.3	H213L	Pathogenic	0.998
USH2A	O75445-1.3	H213M	Pathogenic	0.995
USH2A	O75445-1.3	H213N	Pathogenic	0.887
USH2A	O75445-1.3	H213P	Pathogenic	0.986
USH2A	O75445-1.3	H213Q	Pathogenic	0.963
USH2A	O75445-1.3	H213R	Pathogenic	0.944
USH2A	O75445-1.3	H213S	Pathogenic	0.936
USH2A	O75445-1.3	H213T	Pathogenic	0.984
USH2A	O75445-1.3	H213V	Pathogenic	0.997
USH2A	O75445-1.3	H213W	Pathogenic	0.989
USH2A	O75445-1.3	H213Y	Pathogenic	0.777
USH2A	O75445-1.3	L214A	Pathogenic	0.716
USH2A	O75445-1.3	L214C	Pathogenic	0.769
USH2A	O75445-1.3	L214D	Pathogenic	0.991
USH2A	O75445-1.3	L214E	Pathogenic	0.988
USH2A	O75445-1.3	L214F	Pathogenic	0.717
USH2A	O75445-1.3	L214G	Pathogenic	0.95
USH2A	O75445-1.3	L214H	Pathogenic	0.987
USH2A	O75445-1.3	L214I	Neutral	0.411
USH2A	O75445-1.3	L214K	Pathogenic	0.98
USH2A	O75445-1.3	L214M	Neutral	0.455
USH2A	O75445-1.3	L214N	Pathogenic	0.981
USH2A	O75445-1.3	L214P	Pathogenic	0.957
USH2A	O75445-1.3	L214Q	Pathogenic	0.971
USH2A	O75445-1.3	L214R	Pathogenic	0.97
USH2A	O75445-1.3	L214S	Pathogenic	0.892
USH2A	O75445-1.3	L214T	Pathogenic	0.856
USH2A	O75445-1.3	L214V	Pathogenic	0.511
USH2A	O75445-1.3	L214W	Pathogenic	0.871
USH2A	O75445-1.3	L214Y	Pathogenic	0.868
USH2A	O75445-1.3	S215A	Neutral	0.066
USH2A	O75445-1.3	S215C	Neutral	0.293
USH2A	O75445-1.3	S215D	Neutral	0.118
USH2A	O75445-1.3	S215E	Neutral	0.066
USH2A	O75445-1.3	S215F	Neutral	0.227
USH2A	O75445-1.3	S215G	Neutral	0.07
USH2A	O75445-1.3	S215H	Neutral	0.089
USH2A	O75445-1.3	S215I	Neutral	0.296
USH2A	O75445-1.3	S215K	Neutral	0.035
USH2A	O75445-1.3	S215L	Neutral	0.285
USH2A	O75445-1.3	S215M	Neutral	0.122
USH2A	O75445-1.3	S215N	Neutral	0.044
USH2A	O75445-1.3	S215P	Neutral	0.242
USH2A	O75445-1.3	S215Q	Neutral	0.046
USH2A	O75445-1.3	S215R	Neutral	0.052
USH2A	O75445-1.3	S215T	Neutral	0.042
USH2A	O75445-1.3	S215V	Neutral	0.366
USH2A	O75445-1.3	S215W	Neutral	0.255
USH2A	O75445-1.3	S215Y	Neutral	0.138
USH2A	O75445-1.3	V216A	Neutral	0.315
USH2A	O75445-1.3	V216C	Pathogenic	0.581
USH2A	O75445-1.3	V216D	Pathogenic	0.953
USH2A	O75445-1.3	V216E	Pathogenic	0.92
USH2A	O75445-1.3	V216F	Pathogenic	0.535
USH2A	O75445-1.3	V216G	Pathogenic	0.776
USH2A	O75445-1.3	V216H	Pathogenic	0.93
USH2A	O75445-1.3	V216I	Neutral	0.057
USH2A	O75445-1.3	V216K	Pathogenic	0.855
USH2A	O75445-1.3	V216L	Neutral	0.231
USH2A	O75445-1.3	V216M	Neutral	0.192
USH2A	O75445-1.3	V216N	Pathogenic	0.956
USH2A	O75445-1.3	V216P	Pathogenic	0.804
USH2A	O75445-1.3	V216Q	Pathogenic	0.888
USH2A	O75445-1.3	V216R	Pathogenic	0.9
USH2A	O75445-1.3	V216S	Pathogenic	0.776
USH2A	O75445-1.3	V216T	Pathogenic	0.521
USH2A	O75445-1.3	V216W	Pathogenic	0.754
USH2A	O75445-1.3	V216Y	Neutral	0.448
USH2A	O75445-1.3	Q217A	Pathogenic	0.929
USH2A	O75445-1.3	Q217C	Pathogenic	0.994
USH2A	O75445-1.3	Q217D	Pathogenic	0.926
USH2A	O75445-1.3	Q217E	Pathogenic	0.801
USH2A	O75445-1.3	Q217F	Pathogenic	0.997
USH2A	O75445-1.3	Q217G	Pathogenic	0.933
USH2A	O75445-1.3	Q217H	Pathogenic	0.954
USH2A	O75445-1.3	Q217I	Pathogenic	0.998
USH2A	O75445-1.3	Q217K	Pathogenic	0.867
USH2A	O75445-1.3	Q217L	Pathogenic	0.995
USH2A	O75445-1.3	Q217M	Pathogenic	0.968
USH2A	O75445-1.3	Q217N	Pathogenic	0.931
USH2A	O75445-1.3	Q217P	Pathogenic	0.971
USH2A	O75445-1.3	Q217R	Pathogenic	0.813
USH2A	O75445-1.3	Q217S	Pathogenic	0.855
USH2A	O75445-1.3	Q217T	Pathogenic	0.967
USH2A	O75445-1.3	Q217V	Pathogenic	0.994
USH2A	O75445-1.3	Q217W	Pathogenic	0.987
USH2A	O75445-1.3	Q217Y	Pathogenic	0.972
USH2A	O75445-1.3	V218A	Pathogenic	0.542
USH2A	O75445-1.3	V218C	Pathogenic	0.781
USH2A	O75445-1.3	V218D	Pathogenic	0.981
USH2A	O75445-1.3	V218E	Pathogenic	0.967
USH2A	O75445-1.3	V218F	Pathogenic	0.747
USH2A	O75445-1.3	V218G	Pathogenic	0.899
USH2A	O75445-1.3	V218H	Pathogenic	0.972
USH2A	O75445-1.3	V218I	Neutral	0.135
USH2A	O75445-1.3	V218K	Pathogenic	0.938
USH2A	O75445-1.3	V218L	Neutral	0.436
USH2A	O75445-1.3	V218M	Neutral	0.38
USH2A	O75445-1.3	V218N	Pathogenic	0.983
USH2A	O75445-1.3	V218P	Pathogenic	0.913
USH2A	O75445-1.3	V218Q	Pathogenic	0.953
USH2A	O75445-1.3	V218R	Pathogenic	0.958
USH2A	O75445-1.3	V218S	Pathogenic	0.899
USH2A	O75445-1.3	V218T	Pathogenic	0.737
USH2A	O75445-1.3	V218W	Pathogenic	0.887
USH2A	O75445-1.3	V218Y	Pathogenic	0.676
USH2A	O75445-1.3	H219A	Pathogenic	0.82
USH2A	O75445-1.3	H219C	Pathogenic	0.964
USH2A	O75445-1.3	H219D	Pathogenic	0.861
USH2A	O75445-1.3	H219E	Pathogenic	0.819
USH2A	O75445-1.3	H219F	Pathogenic	0.925
USH2A	O75445-1.3	H219G	Pathogenic	0.708
USH2A	O75445-1.3	H219I	Pathogenic	0.989
USH2A	O75445-1.3	H219K	Pathogenic	0.905
USH2A	O75445-1.3	H219L	Pathogenic	0.989
USH2A	O75445-1.3	H219M	Pathogenic	0.968
USH2A	O75445-1.3	H219N	Pathogenic	0.562
USH2A	O75445-1.3	H219P	Pathogenic	0.921
USH2A	O75445-1.3	H219Q	Pathogenic	0.812
USH2A	O75445-1.3	H219R	Pathogenic	0.734
USH2A	O75445-1.3	H219S	Pathogenic	0.707
USH2A	O75445-1.3	H219T	Pathogenic	0.911
USH2A	O75445-1.3	H219V	Pathogenic	0.982
USH2A	O75445-1.3	H219W	Pathogenic	0.936
USH2A	O75445-1.3	H219Y	Neutral	0.363
USH2A	O75445-1.3	Q220A	Neutral	0.028
USH2A	O75445-1.3	Q220C	Neutral	0.279
USH2A	O75445-1.3	Q220D	Neutral	0.027
USH2A	O75445-1.3	Q220E	Neutral	0.009
USH2A	O75445-1.3	Q220F	Neutral	0.419
USH2A	O75445-1.3	Q220G	Neutral	0.03
USH2A	O75445-1.3	Q220H	Neutral	0.044
USH2A	O75445-1.3	Q220I	Pathogenic	0.509
USH2A	O75445-1.3	Q220K	Neutral	0.014
USH2A	O75445-1.3	Q220L	Neutral	0.301
USH2A	O75445-1.3	Q220M	Neutral	0.061
USH2A	O75445-1.3	Q220N	Neutral	0.029
USH2A	O75445-1.3	Q220P	Neutral	0.069
USH2A	O75445-1.3	Q220R	Neutral	0.009
USH2A	O75445-1.3	Q220S	Neutral	0.013
USH2A	O75445-1.3	Q220T	Neutral	0.061
USH2A	O75445-1.3	Q220V	Neutral	0.259
USH2A	O75445-1.3	Q220W	Neutral	0.139
USH2A	O75445-1.3	Q220Y	Neutral	0.07
USH2A	O75445-1.3	T221A	Neutral	0.063
USH2A	O75445-1.3	T221C	Neutral	0.283
USH2A	O75445-1.3	T221D	Neutral	0.35
USH2A	O75445-1.3	T221E	Neutral	0.244
USH2A	O75445-1.3	T221F	Neutral	0.305
USH2A	O75445-1.3	T221G	Neutral	0.174
USH2A	O75445-1.3	T221H	Neutral	0.273
USH2A	O75445-1.3	T221I	Neutral	0.216
USH2A	O75445-1.3	T221K	Neutral	0.143
USH2A	O75445-1.3	T221L	Neutral	0.207
USH2A	O75445-1.3	T221M	Neutral	0.171
USH2A	O75445-1.3	T221N	Neutral	0.174
USH2A	O75445-1.3	T221P	Neutral	0.283
USH2A	O75445-1.3	T221Q	Neutral	0.182
USH2A	O75445-1.3	T221R	Neutral	0.099
USH2A	O75445-1.3	T221S	Neutral	0.039
USH2A	O75445-1.3	T221V	Neutral	0.142
USH2A	O75445-1.3	T221W	Neutral	0.183
USH2A	O75445-1.3	T221Y	Neutral	0.193
USH2A	O75445-1.3	K222A	Neutral	0.104
USH2A	O75445-1.3	K222C	Pathogenic	0.608
USH2A	O75445-1.3	K222D	Neutral	0.128
USH2A	O75445-1.3	K222E	Neutral	0.051
USH2A	O75445-1.3	K222F	Pathogenic	0.918
USH2A	O75445-1.3	K222G	Neutral	0.11
USH2A	O75445-1.3	K222H	Neutral	0.353
USH2A	O75445-1.3	K222I	Pathogenic	0.888
USH2A	O75445-1.3	K222L	Pathogenic	0.767
USH2A	O75445-1.3	K222M	Pathogenic	0.533
USH2A	O75445-1.3	K222N	Neutral	0.076
USH2A	O75445-1.3	K222P	Neutral	0.229
USH2A	O75445-1.3	K222Q	Neutral	0.072
USH2A	O75445-1.3	K222R	Neutral	0.029
USH2A	O75445-1.3	K222S	Neutral	0.049
USH2A	O75445-1.3	K222T	Neutral	0.206
USH2A	O75445-1.3	K222V	Pathogenic	0.585
USH2A	O75445-1.3	K222W	Pathogenic	0.851
USH2A	O75445-1.3	K222Y	Pathogenic	0.728
USH2A	O75445-1.3	I223A	Neutral	0.422
USH2A	O75445-1.3	I223C	Neutral	0.49
USH2A	O75445-1.3	I223D	Pathogenic	0.934
USH2A	O75445-1.3	I223E	Pathogenic	0.959
USH2A	O75445-1.3	I223F	Neutral	0.402
USH2A	O75445-1.3	I223G	Pathogenic	0.846
USH2A	O75445-1.3	I223H	Pathogenic	0.955
USH2A	O75445-1.3	I223K	Pathogenic	0.97
USH2A	O75445-1.3	I223L	Neutral	0.161
USH2A	O75445-1.3	I223M	Neutral	0.356
USH2A	O75445-1.3	I223N	Pathogenic	0.938
USH2A	O75445-1.3	I223P	Pathogenic	0.867
USH2A	O75445-1.3	I223Q	Pathogenic	0.957
USH2A	O75445-1.3	I223R	Pathogenic	0.955
USH2A	O75445-1.3	I223S	Pathogenic	0.706
USH2A	O75445-1.3	I223T	Pathogenic	0.634
USH2A	O75445-1.3	I223V	Neutral	0.055
USH2A	O75445-1.3	I223W	Pathogenic	0.801
USH2A	O75445-1.3	I223Y	Pathogenic	0.656
USH2A	O75445-1.3	S224A	Neutral	0.381
USH2A	O75445-1.3	S224C	Pathogenic	0.782
USH2A	O75445-1.3	S224D	Pathogenic	0.537
USH2A	O75445-1.3	S224E	Neutral	0.378
USH2A	O75445-1.3	S224F	Pathogenic	0.717
USH2A	O75445-1.3	S224G	Neutral	0.396
USH2A	O75445-1.3	S224H	Neutral	0.456
USH2A	O75445-1.3	S224I	Pathogenic	0.784
USH2A	O75445-1.3	S224K	Neutral	0.239
USH2A	O75445-1.3	S224L	Pathogenic	0.775
USH2A	O75445-1.3	S224M	Pathogenic	0.545
USH2A	O75445-1.3	S224N	Neutral	0.284
USH2A	O75445-1.3	S224P	Pathogenic	0.734
USH2A	O75445-1.3	S224Q	Neutral	0.296
USH2A	O75445-1.3	S224R	Neutral	0.323
USH2A	O75445-1.3	S224T	Neutral	0.277
USH2A	O75445-1.3	S224V	Pathogenic	0.833
USH2A	O75445-1.3	S224W	Pathogenic	0.747
USH2A	O75445-1.3	S224Y	Pathogenic	0.58
USH2A	O75445-1.3	F225A	Pathogenic	0.843
USH2A	O75445-1.3	F225C	Pathogenic	0.876
USH2A	O75445-1.3	F225D	Pathogenic	0.978
USH2A	O75445-1.3	F225E	Pathogenic	0.987
USH2A	O75445-1.3	F225G	Pathogenic	0.886
USH2A	O75445-1.3	F225H	Pathogenic	0.93
USH2A	O75445-1.3	F225I	Pathogenic	0.757
USH2A	O75445-1.3	F225K	Pathogenic	0.995
USH2A	O75445-1.3	F225L	Pathogenic	0.763
USH2A	O75445-1.3	F225M	Pathogenic	0.803
USH2A	O75445-1.3	F225N	Pathogenic	0.98
USH2A	O75445-1.3	F225P	Pathogenic	0.98
USH2A	O75445-1.3	F225Q	Pathogenic	0.986
USH2A	O75445-1.3	F225R	Pathogenic	0.993
USH2A	O75445-1.3	F225S	Pathogenic	0.886
USH2A	O75445-1.3	F225T	Pathogenic	0.927
USH2A	O75445-1.3	F225V	Pathogenic	0.836
USH2A	O75445-1.3	F225W	Neutral	0.496
USH2A	O75445-1.3	F225Y	Neutral	0.315
USH2A	O75445-1.3	F226A	Pathogenic	0.969
USH2A	O75445-1.3	F226C	Pathogenic	0.976
USH2A	O75445-1.3	F226D	Pathogenic	0.996
USH2A	O75445-1.3	F226E	Pathogenic	0.998
USH2A	O75445-1.3	F226G	Pathogenic	0.978
USH2A	O75445-1.3	F226H	Pathogenic	0.987
USH2A	O75445-1.3	F226I	Pathogenic	0.947
USH2A	O75445-1.3	F226K	Pathogenic	0.999
USH2A	O75445-1.3	F226L	Pathogenic	0.949
USH2A	O75445-1.3	F226M	Pathogenic	0.959
USH2A	O75445-1.3	F226N	Pathogenic	0.996
USH2A	O75445-1.3	F226P	Pathogenic	0.996
USH2A	O75445-1.3	F226Q	Pathogenic	0.998
USH2A	O75445-1.3	F226R	Pathogenic	0.999
USH2A	O75445-1.3	F226S	Pathogenic	0.978
USH2A	O75445-1.3	F226T	Pathogenic	0.986
USH2A	O75445-1.3	F226V	Pathogenic	0.967
USH2A	O75445-1.3	F226W	Pathogenic	0.85
USH2A	O75445-1.3	F226Y	Pathogenic	0.725
USH2A	O75445-1.3	I227A	Neutral	0.319
USH2A	O75445-1.3	I227C	Neutral	0.382
USH2A	O75445-1.3	I227D	Pathogenic	0.9
USH2A	O75445-1.3	I227E	Pathogenic	0.938
USH2A	O75445-1.3	I227F	Neutral	0.301
USH2A	O75445-1.3	I227G	Pathogenic	0.78
USH2A	O75445-1.3	I227H	Pathogenic	0.932
USH2A	O75445-1.3	I227K	Pathogenic	0.953
USH2A	O75445-1.3	I227L	Neutral	0.11
USH2A	O75445-1.3	I227M	Neutral	0.262
USH2A	O75445-1.3	I227N	Pathogenic	0.907
USH2A	O75445-1.3	I227P	Pathogenic	0.807
USH2A	O75445-1.3	I227Q	Pathogenic	0.935
USH2A	O75445-1.3	I227R	Pathogenic	0.931
USH2A	O75445-1.3	I227S	Pathogenic	0.607
USH2A	O75445-1.3	I227T	Pathogenic	0.526
USH2A	O75445-1.3	I227V	Neutral	0.036
USH2A	O75445-1.3	I227W	Pathogenic	0.722
USH2A	O75445-1.3	I227Y	Pathogenic	0.551
USH2A	O75445-1.3	N228A	Pathogenic	0.866
USH2A	O75445-1.3	N228C	Pathogenic	0.974
USH2A	O75445-1.3	N228D	Neutral	0.448
USH2A	O75445-1.3	N228E	Pathogenic	0.573
USH2A	O75445-1.3	N228F	Pathogenic	0.957
USH2A	O75445-1.3	N228G	Neutral	0.366
USH2A	O75445-1.3	N228H	Neutral	0.384
USH2A	O75445-1.3	N228I	Pathogenic	0.97
USH2A	O75445-1.3	N228K	Neutral	0.41
USH2A	O75445-1.3	N228L	Pathogenic	0.968
USH2A	O75445-1.3	N228M	Pathogenic	0.913
USH2A	O75445-1.3	N228P	Pathogenic	0.943
USH2A	O75445-1.3	N228Q	Pathogenic	0.576
USH2A	O75445-1.3	N228R	Neutral	0.315
USH2A	O75445-1.3	N228S	Neutral	0.357
USH2A	O75445-1.3	N228T	Pathogenic	0.736
USH2A	O75445-1.3	N228V	Pathogenic	0.978
USH2A	O75445-1.3	N228W	Pathogenic	0.963
USH2A	O75445-1.3	N228Y	Pathogenic	0.842
USH2A	O75445-1.3	G229A	Pathogenic	0.806
USH2A	O75445-1.3	G229C	Pathogenic	0.974
USH2A	O75445-1.3	G229D	Pathogenic	0.847
USH2A	O75445-1.3	G229E	Pathogenic	0.869
USH2A	O75445-1.3	G229F	Pathogenic	0.921
USH2A	O75445-1.3	G229H	Pathogenic	0.794
USH2A	O75445-1.3	G229I	Pathogenic	0.974
USH2A	O75445-1.3	G229K	Pathogenic	0.774
USH2A	O75445-1.3	G229L	Pathogenic	0.973
USH2A	O75445-1.3	G229M	Pathogenic	0.926
USH2A	O75445-1.3	G229N	Pathogenic	0.655
USH2A	O75445-1.3	G229P	Pathogenic	0.927
USH2A	O75445-1.3	G229Q	Pathogenic	0.821
USH2A	O75445-1.3	G229R	Pathogenic	0.694
USH2A	O75445-1.3	G229S	Pathogenic	0.75
USH2A	O75445-1.3	G229T	Pathogenic	0.902
USH2A	O75445-1.3	G229V	Pathogenic	0.958
USH2A	O75445-1.3	G229W	Pathogenic	0.723
USH2A	O75445-1.3	G229Y	Pathogenic	0.864
USH2A	O75445-1.3	V230A	Neutral	0.03
USH2A	O75445-1.3	V230C	Neutral	0.084
USH2A	O75445-1.3	V230D	Pathogenic	0.572
USH2A	O75445-1.3	V230E	Neutral	0.431
USH2A	O75445-1.3	V230F	Neutral	0.071
USH2A	O75445-1.3	V230G	Neutral	0.187
USH2A	O75445-1.3	V230H	Neutral	0.469
USH2A	O75445-1.3	V230I	Neutral	0.004
USH2A	O75445-1.3	V230K	Neutral	0.281
USH2A	O75445-1.3	V230L	Neutral	0.019
USH2A	O75445-1.3	V230M	Neutral	0.015
USH2A	O75445-1.3	V230N	Pathogenic	0.591
USH2A	O75445-1.3	V230P	Neutral	0.213
USH2A	O75445-1.3	V230Q	Neutral	0.344
USH2A	O75445-1.3	V230R	Neutral	0.372
USH2A	O75445-1.3	V230S	Neutral	0.186
USH2A	O75445-1.3	V230T	Neutral	0.067
USH2A	O75445-1.3	V230W	Neutral	0.169
USH2A	O75445-1.3	V230Y	Neutral	0.051
USH2A	O75445-1.3	E231A	Pathogenic	0.916
USH2A	O75445-1.3	E231C	Pathogenic	0.997
USH2A	O75445-1.3	E231D	Pathogenic	0.568
USH2A	O75445-1.3	E231F	Pathogenic	0.995
USH2A	O75445-1.3	E231G	Pathogenic	0.92
USH2A	O75445-1.3	E231H	Pathogenic	0.926
USH2A	O75445-1.3	E231I	Pathogenic	0.996
USH2A	O75445-1.3	E231K	Pathogenic	0.722
USH2A	O75445-1.3	E231L	Pathogenic	0.996
USH2A	O75445-1.3	E231M	Pathogenic	0.989
USH2A	O75445-1.3	E231N	Pathogenic	0.885
USH2A	O75445-1.3	E231P	Pathogenic	0.965
USH2A	O75445-1.3	E231Q	Pathogenic	0.697
USH2A	O75445-1.3	E231R	Pathogenic	0.797
USH2A	O75445-1.3	E231S	Pathogenic	0.829
USH2A	O75445-1.3	E231T	Pathogenic	0.961
USH2A	O75445-1.3	E231V	Pathogenic	0.992
USH2A	O75445-1.3	E231W	Pathogenic	0.99
USH2A	O75445-1.3	E231Y	Pathogenic	0.979
USH2A	O75445-1.3	K232A	Neutral	0.06
USH2A	O75445-1.3	K232C	Neutral	0.463
USH2A	O75445-1.3	K232D	Neutral	0.075
USH2A	O75445-1.3	K232E	Neutral	0.029
USH2A	O75445-1.3	K232F	Pathogenic	0.861
USH2A	O75445-1.3	K232G	Neutral	0.064
USH2A	O75445-1.3	K232H	Neutral	0.233
USH2A	O75445-1.3	K232I	Pathogenic	0.815
USH2A	O75445-1.3	K232L	Pathogenic	0.646
USH2A	O75445-1.3	K232M	Neutral	0.388
USH2A	O75445-1.3	K232N	Neutral	0.043
USH2A	O75445-1.3	K232P	Neutral	0.142
USH2A	O75445-1.3	K232Q	Neutral	0.041
USH2A	O75445-1.3	K232R	Neutral	0.016
USH2A	O75445-1.3	K232S	Neutral	0.028
USH2A	O75445-1.3	K232T	Neutral	0.126
USH2A	O75445-1.3	K232V	Neutral	0.439
USH2A	O75445-1.3	K232W	Pathogenic	0.761
USH2A	O75445-1.3	K232Y	Pathogenic	0.598
USH2A	O75445-1.3	D233A	Pathogenic	0.941
USH2A	O75445-1.3	D233C	Pathogenic	0.989
USH2A	O75445-1.3	D233E	Neutral	0.308
USH2A	O75445-1.3	D233F	Pathogenic	0.976
USH2A	O75445-1.3	D233G	Pathogenic	0.765
USH2A	O75445-1.3	D233H	Pathogenic	0.853
USH2A	O75445-1.3	D233I	Pathogenic	0.983
USH2A	O75445-1.3	D233K	Pathogenic	0.706
USH2A	O75445-1.3	D233L	Pathogenic	0.992
USH2A	O75445-1.3	D233M	Pathogenic	0.977
USH2A	O75445-1.3	D233N	Pathogenic	0.611
USH2A	O75445-1.3	D233P	Pathogenic	0.947
USH2A	O75445-1.3	D233Q	Pathogenic	0.709
USH2A	O75445-1.3	D233R	Pathogenic	0.784
USH2A	O75445-1.3	D233S	Pathogenic	0.758
USH2A	O75445-1.3	D233T	Pathogenic	0.932
USH2A	O75445-1.3	D233V	Pathogenic	0.987
USH2A	O75445-1.3	D233W	Pathogenic	0.979
USH2A	O75445-1.3	D233Y	Pathogenic	0.956
USH2A	O75445-1.3	H234A	Neutral	0.047
USH2A	O75445-1.3	H234C	Neutral	0.227
USH2A	O75445-1.3	H234D	Neutral	0.063
USH2A	O75445-1.3	H234E	Neutral	0.047
USH2A	O75445-1.3	H234F	Neutral	0.12
USH2A	O75445-1.3	H234G	Neutral	0.026
USH2A	O75445-1.3	H234I	Pathogenic	0.504
USH2A	O75445-1.3	H234K	Neutral	0.094
USH2A	O75445-1.3	H234L	Neutral	0.491
USH2A	O75445-1.3	H234M	Neutral	0.251
USH2A	O75445-1.3	H234N	Neutral	0.014
USH2A	O75445-1.3	H234P	Neutral	0.113
USH2A	O75445-1.3	H234Q	Neutral	0.045
USH2A	O75445-1.3	H234R	Neutral	0.029
USH2A	O75445-1.3	H234S	Neutral	0.026
USH2A	O75445-1.3	H234T	Neutral	0.101
USH2A	O75445-1.3	H234V	Neutral	0.377
USH2A	O75445-1.3	H234W	Neutral	0.137
USH2A	O75445-1.3	H234Y	Neutral	0.006
USH2A	O75445-1.3	T235A	Neutral	0.499
USH2A	O75445-1.3	T235C	Pathogenic	0.854
USH2A	O75445-1.3	T235D	Pathogenic	0.889
USH2A	O75445-1.3	T235E	Pathogenic	0.827
USH2A	O75445-1.3	T235F	Pathogenic	0.867
USH2A	O75445-1.3	T235G	Pathogenic	0.758
USH2A	O75445-1.3	T235H	Pathogenic	0.848
USH2A	O75445-1.3	T235I	Pathogenic	0.803
USH2A	O75445-1.3	T235K	Pathogenic	0.711
USH2A	O75445-1.3	T235L	Pathogenic	0.795
USH2A	O75445-1.3	T235M	Pathogenic	0.754
USH2A	O75445-1.3	T235N	Pathogenic	0.757
USH2A	O75445-1.3	T235P	Pathogenic	0.854
USH2A	O75445-1.3	T235Q	Pathogenic	0.768
USH2A	O75445-1.3	T235R	Pathogenic	0.621
USH2A	O75445-1.3	T235S	Neutral	0.374
USH2A	O75445-1.3	T235V	Pathogenic	0.711
USH2A	O75445-1.3	T235W	Pathogenic	0.769
USH2A	O75445-1.3	T235Y	Pathogenic	0.78
USH2A	O75445-1.3	P236A	Neutral	0.262
USH2A	O75445-1.3	P236C	Pathogenic	0.76
USH2A	O75445-1.3	P236D	Pathogenic	0.552
USH2A	O75445-1.3	P236E	Neutral	0.393
USH2A	O75445-1.3	P236F	Pathogenic	0.744
USH2A	O75445-1.3	P236G	Neutral	0.34
USH2A	O75445-1.3	P236H	Neutral	0.43
USH2A	O75445-1.3	P236I	Pathogenic	0.646
USH2A	O75445-1.3	P236K	Neutral	0.251
USH2A	O75445-1.3	P236L	Pathogenic	0.634
USH2A	O75445-1.3	P236M	Neutral	0.375
USH2A	O75445-1.3	P236N	Pathogenic	0.688
USH2A	O75445-1.3	P236Q	Neutral	0.309
USH2A	O75445-1.3	P236R	Neutral	0.336
USH2A	O75445-1.3	P236S	Neutral	0.339
USH2A	O75445-1.3	P236T	Neutral	0.41
USH2A	O75445-1.3	P236V	Pathogenic	0.523
USH2A	O75445-1.3	P236W	Pathogenic	0.597
USH2A	O75445-1.3	P236Y	Neutral	0.41
USH2A	O75445-1.3	F237A	Pathogenic	0.938
USH2A	O75445-1.3	F237C	Pathogenic	0.952
USH2A	O75445-1.3	F237D	Pathogenic	0.992
USH2A	O75445-1.3	F237E	Pathogenic	0.995
USH2A	O75445-1.3	F237G	Pathogenic	0.957
USH2A	O75445-1.3	F237H	Pathogenic	0.974
USH2A	O75445-1.3	F237I	Pathogenic	0.898
USH2A	O75445-1.3	F237K	Pathogenic	0.998
USH2A	O75445-1.3	F237L	Pathogenic	0.901
USH2A	O75445-1.3	F237M	Pathogenic	0.92
USH2A	O75445-1.3	F237N	Pathogenic	0.993
USH2A	O75445-1.3	F237P	Pathogenic	0.993
USH2A	O75445-1.3	F237Q	Pathogenic	0.995
USH2A	O75445-1.3	F237R	Pathogenic	0.997
USH2A	O75445-1.3	F237S	Pathogenic	0.956
USH2A	O75445-1.3	F237T	Pathogenic	0.973
USH2A	O75445-1.3	F237V	Pathogenic	0.935
USH2A	O75445-1.3	F237W	Pathogenic	0.736
USH2A	O75445-1.3	F237Y	Pathogenic	0.565
USH2A	O75445-1.3	N238A	Neutral	0.263
USH2A	O75445-1.3	N238C	Pathogenic	0.677
USH2A	O75445-1.3	N238D	Neutral	0.043
USH2A	O75445-1.3	N238E	Neutral	0.069
USH2A	O75445-1.3	N238F	Pathogenic	0.552
USH2A	O75445-1.3	N238G	Neutral	0.031
USH2A	O75445-1.3	N238H	Neutral	0.033
USH2A	O75445-1.3	N238I	Pathogenic	0.638
USH2A	O75445-1.3	N238K	Neutral	0.037
USH2A	O75445-1.3	N238L	Pathogenic	0.626
USH2A	O75445-1.3	N238M	Neutral	0.368
USH2A	O75445-1.3	N238P	Neutral	0.477
USH2A	O75445-1.3	N238Q	Neutral	0.07
USH2A	O75445-1.3	N238R	Neutral	0.025
USH2A	O75445-1.3	N238S	Neutral	0.03
USH2A	O75445-1.3	N238T	Neutral	0.133
USH2A	O75445-1.3	N238V	Pathogenic	0.708
USH2A	O75445-1.3	N238W	Pathogenic	0.59
USH2A	O75445-1.3	N238Y	Neutral	0.227
USH2A	O75445-1.3	A239C	Neutral	0.079
USH2A	O75445-1.3	A239D	Neutral	0.317
USH2A	O75445-1.3	A239E	Neutral	0.097
USH2A	O75445-1.3	A239F	Neutral	0.121
USH2A	O75445-1.3	A239G	Neutral	0.067
USH2A	O75445-1.3	A239H	Neutral	0.111
USH2A	O75445-1.3	A239I	Neutral	0.08
USH2A	O75445-1.3	A239K	Neutral	0.052
USH2A	O75445-1.3	A239L	Neutral	0.076
USH2A	O75445-1.3	A239M	Neutral	0.061
USH2A	O75445-1.3	A239N	Neutral	0.267
USH2A	O75445-1.3	A239P	Neutral	0.131
USH2A	O75445-1.3	A239Q	Neutral	0.069
USH2A	O75445-1.3	A239R	Neutral	0.035
USH2A	O75445-1.3	A239S	Neutral	0.046
USH2A	O75445-1.3	A239T	Neutral	0.048
USH2A	O75445-1.3	A239V	Neutral	0.05
USH2A	O75445-1.3	A239W	Neutral	0.139
USH2A	O75445-1.3	A239Y	Neutral	0.07
USH2A	O75445-1.3	R240A	Neutral	0.163
USH2A	O75445-1.3	R240C	Pathogenic	0.723
USH2A	O75445-1.3	R240D	Neutral	0.36
USH2A	O75445-1.3	R240E	Neutral	0.171
USH2A	O75445-1.3	R240F	Pathogenic	0.95
USH2A	O75445-1.3	R240G	Neutral	0.172
USH2A	O75445-1.3	R240H	Neutral	0.287
USH2A	O75445-1.3	R240I	Pathogenic	0.93
USH2A	O75445-1.3	R240K	Neutral	0.071
USH2A	O75445-1.3	R240L	Pathogenic	0.847
USH2A	O75445-1.3	R240M	Pathogenic	0.658
USH2A	O75445-1.3	R240N	Neutral	0.121
USH2A	O75445-1.3	R240P	Pathogenic	0.533
USH2A	O75445-1.3	R240Q	Neutral	0.115
USH2A	O75445-1.3	R240S	Neutral	0.166
USH2A	O75445-1.3	R240T	Neutral	0.305
USH2A	O75445-1.3	R240V	Pathogenic	0.844
USH2A	O75445-1.3	R240W	Pathogenic	0.957
USH2A	O75445-1.3	R240Y	Pathogenic	0.869
USH2A	O75445-1.3	T241A	Neutral	0.021
USH2A	O75445-1.3	T241C	Neutral	0.113
USH2A	O75445-1.3	T241D	Neutral	0.148
USH2A	O75445-1.3	T241E	Neutral	0.094
USH2A	O75445-1.3	T241F	Neutral	0.123
USH2A	O75445-1.3	T241G	Neutral	0.064
USH2A	O75445-1.3	T241H	Neutral	0.108
USH2A	O75445-1.3	T241I	Neutral	0.081
USH2A	O75445-1.3	T241K	Neutral	0.051
USH2A	O75445-1.3	T241L	Neutral	0.078
USH2A	O75445-1.3	T241M	Neutral	0.062
USH2A	O75445-1.3	T241N	Neutral	0.063
USH2A	O75445-1.3	T241P	Neutral	0.113
USH2A	O75445-1.3	T241Q	Neutral	0.067
USH2A	O75445-1.3	T241R	Neutral	0.034
USH2A	O75445-1.3	T241S	Neutral	0.013
USH2A	O75445-1.3	T241V	Neutral	0.051
USH2A	O75445-1.3	T241W	Neutral	0.067
USH2A	O75445-1.3	T241Y	Neutral	0.071
USH2A	O75445-1.3	L242A	Pathogenic	0.857
USH2A	O75445-1.3	L242C	Pathogenic	0.888
USH2A	O75445-1.3	L242D	Pathogenic	0.996
USH2A	O75445-1.3	L242E	Pathogenic	0.995
USH2A	O75445-1.3	L242F	Pathogenic	0.858
USH2A	O75445-1.3	L242G	Pathogenic	0.978
USH2A	O75445-1.3	L242H	Pathogenic	0.994
USH2A	O75445-1.3	L242I	Pathogenic	0.624
USH2A	O75445-1.3	L242K	Pathogenic	0.991
USH2A	O75445-1.3	L242M	Pathogenic	0.665
USH2A	O75445-1.3	L242N	Pathogenic	0.992
USH2A	O75445-1.3	L242P	Pathogenic	0.982
USH2A	O75445-1.3	L242Q	Pathogenic	0.988
USH2A	O75445-1.3	L242R	Pathogenic	0.987
USH2A	O75445-1.3	L242S	Pathogenic	0.952
USH2A	O75445-1.3	L242T	Pathogenic	0.934
USH2A	O75445-1.3	L242V	Pathogenic	0.713
USH2A	O75445-1.3	L242W	Pathogenic	0.941
USH2A	O75445-1.3	L242Y	Pathogenic	0.94
USH2A	O75445-1.3	S243A	Neutral	0.003
USH2A	O75445-1.3	S243C	Neutral	0.019
USH2A	O75445-1.3	S243D	Neutral	0.006
USH2A	O75445-1.3	S243E	Neutral	0.003
USH2A	O75445-1.3	S243F	Neutral	0.013
USH2A	O75445-1.3	S243G	Neutral	0.003
USH2A	O75445-1.3	S243H	Neutral	0.004
USH2A	O75445-1.3	S243I	Neutral	0.019
USH2A	O75445-1.3	S243K	Neutral	0.002
USH2A	O75445-1.3	S243L	Neutral	0.018
USH2A	O75445-1.3	S243M	Neutral	0.006
USH2A	O75445-1.3	S243N	Neutral	0.002
USH2A	O75445-1.3	S243P	Neutral	0.014
USH2A	O75445-1.3	S243Q	Neutral	0.002
USH2A	O75445-1.3	S243R	Neutral	0.003
USH2A	O75445-1.3	S243T	Neutral	0.002
USH2A	O75445-1.3	S243V	Neutral	0.026
USH2A	O75445-1.3	S243W	Neutral	0.015
USH2A	O75445-1.3	S243Y	Neutral	0.007
USH2A	O75445-1.3	G244A	Neutral	0.271
USH2A	O75445-1.3	G244C	Pathogenic	0.771
USH2A	O75445-1.3	G244D	Neutral	0.331
USH2A	O75445-1.3	G244E	Neutral	0.372
USH2A	O75445-1.3	G244F	Pathogenic	0.51
USH2A	O75445-1.3	G244H	Neutral	0.257
USH2A	O75445-1.3	G244I	Pathogenic	0.773
USH2A	O75445-1.3	G244K	Neutral	0.235
USH2A	O75445-1.3	G244L	Pathogenic	0.764
USH2A	O75445-1.3	G244M	Pathogenic	0.529
USH2A	O75445-1.3	G244N	Neutral	0.145
USH2A	O75445-1.3	G244P	Pathogenic	0.532
USH2A	O75445-1.3	G244Q	Neutral	0.291
USH2A	O75445-1.3	G244R	Neutral	0.169
USH2A	O75445-1.3	G244S	Neutral	0.212
USH2A	O75445-1.3	G244T	Neutral	0.451
USH2A	O75445-1.3	G244V	Pathogenic	0.673
USH2A	O75445-1.3	G244W	Neutral	0.189
USH2A	O75445-1.3	G244Y	Neutral	0.363
USH2A	O75445-1.3	S245A	Neutral	0.009
USH2A	O75445-1.3	S245C	Neutral	0.05
USH2A	O75445-1.3	S245D	Neutral	0.017
USH2A	O75445-1.3	S245E	Neutral	0.009
USH2A	O75445-1.3	S245F	Neutral	0.036
USH2A	O75445-1.3	S245G	Neutral	0.01
USH2A	O75445-1.3	S245H	Neutral	0.012
USH2A	O75445-1.3	S245I	Neutral	0.051
USH2A	O75445-1.3	S245K	Neutral	0.005
USH2A	O75445-1.3	S245L	Neutral	0.048
USH2A	O75445-1.3	S245M	Neutral	0.017
USH2A	O75445-1.3	S245N	Neutral	0.006
USH2A	O75445-1.3	S245P	Neutral	0.039
USH2A	O75445-1.3	S245Q	Neutral	0.006
USH2A	O75445-1.3	S245R	Neutral	0.007
USH2A	O75445-1.3	S245T	Neutral	0.006
USH2A	O75445-1.3	S245V	Neutral	0.069
USH2A	O75445-1.3	S245W	Neutral	0.042
USH2A	O75445-1.3	S245Y	Neutral	0.02
USH2A	O75445-1.3	I246A	Neutral	0.195
USH2A	O75445-1.3	I246C	Neutral	0.242
USH2A	O75445-1.3	I246D	Pathogenic	0.824
USH2A	O75445-1.3	I246E	Pathogenic	0.886
USH2A	O75445-1.3	I246F	Neutral	0.182
USH2A	O75445-1.3	I246G	Pathogenic	0.646
USH2A	O75445-1.3	I246H	Pathogenic	0.877
USH2A	O75445-1.3	I246K	Pathogenic	0.913
USH2A	O75445-1.3	I246L	Neutral	0.06
USH2A	O75445-1.3	I246M	Neutral	0.155
USH2A	O75445-1.3	I246N	Pathogenic	0.835
USH2A	O75445-1.3	I246P	Pathogenic	0.683
USH2A	O75445-1.3	I246Q	Pathogenic	0.881
USH2A	O75445-1.3	I246R	Pathogenic	0.875
USH2A	O75445-1.3	I246S	Neutral	0.444
USH2A	O75445-1.3	I246T	Neutral	0.364
USH2A	O75445-1.3	I246V	Neutral	0.019
USH2A	O75445-1.3	I246W	Pathogenic	0.573
USH2A	O75445-1.3	I246Y	Neutral	0.388
USH2A	O75445-1.3	T247A	Neutral	0.008
USH2A	O75445-1.3	T247C	Neutral	0.046
USH2A	O75445-1.3	T247D	Neutral	0.062
USH2A	O75445-1.3	T247E	Neutral	0.038
USH2A	O75445-1.3	T247F	Neutral	0.051
USH2A	O75445-1.3	T247G	Neutral	0.025
USH2A	O75445-1.3	T247H	Neutral	0.044
USH2A	O75445-1.3	T247I	Neutral	0.033
USH2A	O75445-1.3	T247K	Neutral	0.02
USH2A	O75445-1.3	T247L	Neutral	0.031
USH2A	O75445-1.3	T247M	Neutral	0.025
USH2A	O75445-1.3	T247N	Neutral	0.025
USH2A	O75445-1.3	T247P	Neutral	0.046
USH2A	O75445-1.3	T247Q	Neutral	0.027
USH2A	O75445-1.3	T247R	Neutral	0.013
USH2A	O75445-1.3	T247S	Neutral	0.005
USH2A	O75445-1.3	T247V	Neutral	0.02
USH2A	O75445-1.3	T247W	Neutral	0.027
USH2A	O75445-1.3	T247Y	Neutral	0.029
USH2A	O75445-1.3	D248A	Pathogenic	0.954
USH2A	O75445-1.3	D248C	Pathogenic	0.992
USH2A	O75445-1.3	D248E	Neutral	0.367
USH2A	O75445-1.3	D248F	Pathogenic	0.981
USH2A	O75445-1.3	D248G	Pathogenic	0.809
USH2A	O75445-1.3	D248H	Pathogenic	0.883
USH2A	O75445-1.3	D248I	Pathogenic	0.987
USH2A	O75445-1.3	D248K	Pathogenic	0.758
USH2A	O75445-1.3	D248L	Pathogenic	0.994
USH2A	O75445-1.3	D248M	Pathogenic	0.983
USH2A	O75445-1.3	D248N	Pathogenic	0.672
USH2A	O75445-1.3	D248P	Pathogenic	0.959
USH2A	O75445-1.3	D248Q	Pathogenic	0.76
USH2A	O75445-1.3	D248R	Pathogenic	0.826
USH2A	O75445-1.3	D248S	Pathogenic	0.803
USH2A	O75445-1.3	D248T	Pathogenic	0.947
USH2A	O75445-1.3	D248V	Pathogenic	0.99
USH2A	O75445-1.3	D248W	Pathogenic	0.984
USH2A	O75445-1.3	D248Y	Pathogenic	0.966
USH2A	O75445-1.3	F249A	Neutral	0.025
USH2A	O75445-1.3	F249C	Neutral	0.033
USH2A	O75445-1.3	F249D	Neutral	0.18
USH2A	O75445-1.3	F249E	Neutral	0.269
USH2A	O75445-1.3	F249G	Neutral	0.036
USH2A	O75445-1.3	F249H	Neutral	0.06
USH2A	O75445-1.3	F249I	Neutral	0.015
USH2A	O75445-1.3	F249K	Pathogenic	0.502
USH2A	O75445-1.3	F249L	Neutral	0.015
USH2A	O75445-1.3	F249M	Neutral	0.019
USH2A	O75445-1.3	F249N	Neutral	0.192
USH2A	O75445-1.3	F249P	Neutral	0.188
USH2A	O75445-1.3	F249Q	Neutral	0.259
USH2A	O75445-1.3	F249R	Neutral	0.401
USH2A	O75445-1.3	F249S	Neutral	0.036
USH2A	O75445-1.3	F249T	Neutral	0.058
USH2A	O75445-1.3	F249V	Neutral	0.024
USH2A	O75445-1.3	F249W	Neutral	0.005
USH2A	O75445-1.3	F249Y	Neutral	0.002
USH2A	O75445-1.3	A250C	Neutral	0.081
USH2A	O75445-1.3	A250D	Neutral	0.323
USH2A	O75445-1.3	A250E	Neutral	0.099
USH2A	O75445-1.3	A250F	Neutral	0.124
USH2A	O75445-1.3	A250G	Neutral	0.068
USH2A	O75445-1.3	A250H	Neutral	0.114
USH2A	O75445-1.3	A250I	Neutral	0.082
USH2A	O75445-1.3	A250K	Neutral	0.054
USH2A	O75445-1.3	A250L	Neutral	0.078
USH2A	O75445-1.3	A250M	Neutral	0.063
USH2A	O75445-1.3	A250N	Neutral	0.272
USH2A	O75445-1.3	A250P	Neutral	0.134
USH2A	O75445-1.3	A250Q	Neutral	0.071
USH2A	O75445-1.3	A250R	Neutral	0.036
USH2A	O75445-1.3	A250S	Neutral	0.047
USH2A	O75445-1.3	A250T	Neutral	0.049
USH2A	O75445-1.3	A250V	Neutral	0.051
USH2A	O75445-1.3	A250W	Neutral	0.142
USH2A	O75445-1.3	A250Y	Neutral	0.072
USH2A	O75445-1.3	S251A	Neutral	0.024
USH2A	O75445-1.3	S251C	Neutral	0.127
USH2A	O75445-1.3	S251D	Neutral	0.045
USH2A	O75445-1.3	S251E	Neutral	0.024
USH2A	O75445-1.3	S251F	Neutral	0.093
USH2A	O75445-1.3	S251G	Neutral	0.026
USH2A	O75445-1.3	S251H	Neutral	0.033
USH2A	O75445-1.3	S251I	Neutral	0.128
USH2A	O75445-1.3	S251K	Neutral	0.013
USH2A	O75445-1.3	S251L	Neutral	0.122
USH2A	O75445-1.3	S251M	Neutral	0.046
USH2A	O75445-1.3	S251N	Neutral	0.016
USH2A	O75445-1.3	S251P	Neutral	0.101
USH2A	O75445-1.3	S251Q	Neutral	0.017
USH2A	O75445-1.3	S251R	Neutral	0.019
USH2A	O75445-1.3	S251T	Neutral	0.015
USH2A	O75445-1.3	S251V	Neutral	0.168
USH2A	O75445-1.3	S251W	Neutral	0.107
USH2A	O75445-1.3	S251Y	Neutral	0.053
USH2A	O75445-1.3	G252A	Pathogenic	0.505
USH2A	O75445-1.3	G252C	Pathogenic	0.902
USH2A	O75445-1.3	G252D	Pathogenic	0.576
USH2A	O75445-1.3	G252E	Pathogenic	0.619
USH2A	O75445-1.3	G252F	Pathogenic	0.741
USH2A	O75445-1.3	G252H	Neutral	0.487
USH2A	O75445-1.3	G252I	Pathogenic	0.903
USH2A	O75445-1.3	G252K	Neutral	0.457
USH2A	O75445-1.3	G252L	Pathogenic	0.899
USH2A	O75445-1.3	G252M	Pathogenic	0.755
USH2A	O75445-1.3	G252N	Neutral	0.317
USH2A	O75445-1.3	G252P	Pathogenic	0.757
USH2A	O75445-1.3	G252Q	Pathogenic	0.53
USH2A	O75445-1.3	G252R	Neutral	0.358
USH2A	O75445-1.3	G252S	Neutral	0.424
USH2A	O75445-1.3	G252T	Pathogenic	0.692
USH2A	O75445-1.3	G252V	Pathogenic	0.849
USH2A	O75445-1.3	G252W	Neutral	0.39
USH2A	O75445-1.3	G252Y	Pathogenic	0.609
USH2A	O75445-1.3	T253A	Neutral	0.02
USH2A	O75445-1.3	T253C	Neutral	0.105
USH2A	O75445-1.3	T253D	Neutral	0.138
USH2A	O75445-1.3	T253E	Neutral	0.087
USH2A	O75445-1.3	T253F	Neutral	0.115
USH2A	O75445-1.3	T253G	Neutral	0.059
USH2A	O75445-1.3	T253H	Neutral	0.1
USH2A	O75445-1.3	T253I	Neutral	0.075
USH2A	O75445-1.3	T253K	Neutral	0.047
USH2A	O75445-1.3	T253L	Neutral	0.072
USH2A	O75445-1.3	T253M	Neutral	0.058
USH2A	O75445-1.3	T253N	Neutral	0.059
USH2A	O75445-1.3	T253P	Neutral	0.105
USH2A	O75445-1.3	T253Q	Neutral	0.062
USH2A	O75445-1.3	T253R	Neutral	0.032
USH2A	O75445-1.3	T253S	Neutral	0.012
USH2A	O75445-1.3	T253V	Neutral	0.047
USH2A	O75445-1.3	T253W	Neutral	0.062
USH2A	O75445-1.3	T253Y	Neutral	0.066
USH2A	O75445-1.3	V254A	Neutral	0.005
USH2A	O75445-1.3	V254C	Neutral	0.016
USH2A	O75445-1.3	V254D	Neutral	0.188
USH2A	O75445-1.3	V254E	Neutral	0.116
USH2A	O75445-1.3	V254F	Neutral	0.013
USH2A	O75445-1.3	V254G	Neutral	0.038
USH2A	O75445-1.3	V254H	Neutral	0.133
USH2A	O75445-1.3	V254I	Neutral	0.001
USH2A	O75445-1.3	V254K	Neutral	0.063
USH2A	O75445-1.3	V254L	Neutral	0.003
USH2A	O75445-1.3	V254M	Neutral	0.003
USH2A	O75445-1.3	V254N	Neutral	0.2
USH2A	O75445-1.3	V254P	Neutral	0.045
USH2A	O75445-1.3	V254Q	Neutral	0.083
USH2A	O75445-1.3	V254R	Neutral	0.093
USH2A	O75445-1.3	V254S	Neutral	0.038
USH2A	O75445-1.3	V254T	Neutral	0.012
USH2A	O75445-1.3	V254W	Neutral	0.034
USH2A	O75445-1.3	V254Y	Neutral	0.009
USH2A	O75445-1.3	Q255A	Neutral	0.1
USH2A	O75445-1.3	Q255C	Pathogenic	0.6
USH2A	O75445-1.3	Q255D	Neutral	0.097
USH2A	O75445-1.3	Q255E	Neutral	0.033
USH2A	O75445-1.3	Q255F	Pathogenic	0.737
USH2A	O75445-1.3	Q255G	Neutral	0.106
USH2A	O75445-1.3	Q255H	Neutral	0.151
USH2A	O75445-1.3	Q255I	Pathogenic	0.801
USH2A	O75445-1.3	Q255K	Neutral	0.053
USH2A	O75445-1.3	Q255L	Pathogenic	0.626
USH2A	O75445-1.3	Q255M	Neutral	0.203
USH2A	O75445-1.3	Q255N	Neutral	0.103
USH2A	O75445-1.3	Q255P	Neutral	0.223
USH2A	O75445-1.3	Q255R	Neutral	0.036
USH2A	O75445-1.3	Q255S	Neutral	0.048
USH2A	O75445-1.3	Q255T	Neutral	0.201
USH2A	O75445-1.3	Q255V	Pathogenic	0.576
USH2A	O75445-1.3	Q255W	Neutral	0.386
USH2A	O75445-1.3	Q255Y	Neutral	0.227
USH2A	O75445-1.3	I256A	Pathogenic	0.62
USH2A	O75445-1.3	I256C	Pathogenic	0.682
USH2A	O75445-1.3	I256D	Pathogenic	0.969
USH2A	O75445-1.3	I256E	Pathogenic	0.981
USH2A	O75445-1.3	I256F	Pathogenic	0.6
USH2A	O75445-1.3	I256G	Pathogenic	0.925
USH2A	O75445-1.3	I256H	Pathogenic	0.979
USH2A	O75445-1.3	I256K	Pathogenic	0.986
USH2A	O75445-1.3	I256L	Neutral	0.3
USH2A	O75445-1.3	I256M	Pathogenic	0.552
USH2A	O75445-1.3	I256N	Pathogenic	0.971
USH2A	O75445-1.3	I256P	Pathogenic	0.936
USH2A	O75445-1.3	I256Q	Pathogenic	0.98
USH2A	O75445-1.3	I256R	Pathogenic	0.979
USH2A	O75445-1.3	I256S	Pathogenic	0.843
USH2A	O75445-1.3	I256T	Pathogenic	0.794
USH2A	O75445-1.3	I256V	Neutral	0.115
USH2A	O75445-1.3	I256W	Pathogenic	0.9
USH2A	O75445-1.3	I256Y	Pathogenic	0.81
USH2A	O75445-1.3	G257A	Pathogenic	0.876
USH2A	O75445-1.3	G257C	Pathogenic	0.985
USH2A	O75445-1.3	G257D	Pathogenic	0.904
USH2A	O75445-1.3	G257E	Pathogenic	0.919
USH2A	O75445-1.3	G257F	Pathogenic	0.952
USH2A	O75445-1.3	G257H	Pathogenic	0.868
USH2A	O75445-1.3	G257I	Pathogenic	0.985
USH2A	O75445-1.3	G257K	Pathogenic	0.854
USH2A	O75445-1.3	G257L	Pathogenic	0.984
USH2A	O75445-1.3	G257M	Pathogenic	0.955
USH2A	O75445-1.3	G257N	Pathogenic	0.764
USH2A	O75445-1.3	G257P	Pathogenic	0.956
USH2A	O75445-1.3	G257Q	Pathogenic	0.887
USH2A	O75445-1.3	G257R	Pathogenic	0.795
USH2A	O75445-1.3	G257S	Pathogenic	0.836
USH2A	O75445-1.3	G257T	Pathogenic	0.94
USH2A	O75445-1.3	G257V	Pathogenic	0.975
USH2A	O75445-1.3	G257W	Pathogenic	0.816
USH2A	O75445-1.3	G257Y	Pathogenic	0.916
USH2A	O75445-1.3	Q258A	Neutral	0.351
USH2A	O75445-1.3	Q258C	Pathogenic	0.879
USH2A	O75445-1.3	Q258D	Neutral	0.341
USH2A	O75445-1.3	Q258E	Neutral	0.142
USH2A	O75445-1.3	Q258F	Pathogenic	0.931
USH2A	O75445-1.3	Q258G	Neutral	0.365
USH2A	O75445-1.3	Q258H	Neutral	0.463
USH2A	O75445-1.3	Q258I	Pathogenic	0.951
USH2A	O75445-1.3	Q258K	Neutral	0.212
USH2A	O75445-1.3	Q258L	Pathogenic	0.89
USH2A	O75445-1.3	Q258M	Pathogenic	0.551
USH2A	O75445-1.3	Q258N	Neutral	0.358
USH2A	O75445-1.3	Q258P	Pathogenic	0.581
USH2A	O75445-1.3	Q258R	Neutral	0.151
USH2A	O75445-1.3	Q258S	Neutral	0.195
USH2A	O75445-1.3	Q258T	Pathogenic	0.548
USH2A	O75445-1.3	Q258V	Pathogenic	0.868
USH2A	O75445-1.3	Q258W	Pathogenic	0.752
USH2A	O75445-1.3	Q258Y	Pathogenic	0.587
USH2A	O75445-1.3	S259A	Neutral	0.333
USH2A	O75445-1.3	S259C	Pathogenic	0.744
USH2A	O75445-1.3	S259D	Neutral	0.485
USH2A	O75445-1.3	S259E	Neutral	0.331
USH2A	O75445-1.3	S259F	Pathogenic	0.673
USH2A	O75445-1.3	S259G	Neutral	0.347
USH2A	O75445-1.3	S259H	Neutral	0.406
USH2A	O75445-1.3	S259I	Pathogenic	0.747
USH2A	O75445-1.3	S259K	Neutral	0.204
USH2A	O75445-1.3	S259L	Pathogenic	0.737
USH2A	O75445-1.3	S259M	Neutral	0.493
USH2A	O75445-1.3	S259N	Neutral	0.244
USH2A	O75445-1.3	S259P	Pathogenic	0.692
USH2A	O75445-1.3	S259Q	Neutral	0.255
USH2A	O75445-1.3	S259R	Neutral	0.279
USH2A	O75445-1.3	S259T	Neutral	0.237
USH2A	O75445-1.3	S259V	Pathogenic	0.802
USH2A	O75445-1.3	S259W	Pathogenic	0.706
USH2A	O75445-1.3	S259Y	Pathogenic	0.529
USH2A	O75445-1.3	L260A	Neutral	0.04
USH2A	O75445-1.3	L260C	Neutral	0.052
USH2A	O75445-1.3	L260D	Pathogenic	0.646
USH2A	O75445-1.3	L260E	Pathogenic	0.572
USH2A	O75445-1.3	L260F	Neutral	0.04
USH2A	O75445-1.3	L260G	Neutral	0.239
USH2A	O75445-1.3	L260H	Pathogenic	0.549
USH2A	O75445-1.3	L260I	Neutral	0.011
USH2A	O75445-1.3	L260K	Neutral	0.442
USH2A	O75445-1.3	L260M	Neutral	0.014
USH2A	O75445-1.3	L260N	Neutral	0.464
USH2A	O75445-1.3	L260P	Neutral	0.27
USH2A	O75445-1.3	L260Q	Neutral	0.358
USH2A	O75445-1.3	L260R	Neutral	0.345
USH2A	O75445-1.3	L260S	Neutral	0.12
USH2A	O75445-1.3	L260T	Neutral	0.09
USH2A	O75445-1.3	L260V	Neutral	0.017
USH2A	O75445-1.3	L260W	Neutral	0.1
USH2A	O75445-1.3	L260Y	Neutral	0.098
USH2A	O75445-1.3	N261A	Pathogenic	0.561
USH2A	O75445-1.3	N261C	Pathogenic	0.883
USH2A	O75445-1.3	N261D	Neutral	0.138
USH2A	O75445-1.3	N261E	Neutral	0.21
USH2A	O75445-1.3	N261F	Pathogenic	0.815
USH2A	O75445-1.3	N261G	Neutral	0.103
USH2A	O75445-1.3	N261H	Neutral	0.11
USH2A	O75445-1.3	N261I	Pathogenic	0.864
USH2A	O75445-1.3	N261K	Neutral	0.121
USH2A	O75445-1.3	N261L	Pathogenic	0.858
USH2A	O75445-1.3	N261M	Pathogenic	0.676
USH2A	O75445-1.3	N261P	Pathogenic	0.766
USH2A	O75445-1.3	N261Q	Neutral	0.212
USH2A	O75445-1.3	N261R	Neutral	0.083
USH2A	O75445-1.3	N261S	Neutral	0.099
USH2A	O75445-1.3	N261T	Neutral	0.355
USH2A	O75445-1.3	N261V	Pathogenic	0.897
USH2A	O75445-1.3	N261W	Pathogenic	0.838
USH2A	O75445-1.3	N261Y	Pathogenic	0.514
USH2A	O75445-1.3	G262A	Pathogenic	0.822
USH2A	O75445-1.3	G262C	Pathogenic	0.977
USH2A	O75445-1.3	G262D	Pathogenic	0.86
USH2A	O75445-1.3	G262E	Pathogenic	0.88
USH2A	O75445-1.3	G262F	Pathogenic	0.928
USH2A	O75445-1.3	G262H	Pathogenic	0.811
USH2A	O75445-1.3	G262I	Pathogenic	0.977
USH2A	O75445-1.3	G262K	Pathogenic	0.792
USH2A	O75445-1.3	G262L	Pathogenic	0.976
USH2A	O75445-1.3	G262M	Pathogenic	0.933
USH2A	O75445-1.3	G262N	Pathogenic	0.678
USH2A	O75445-1.3	G262P	Pathogenic	0.934
USH2A	O75445-1.3	G262Q	Pathogenic	0.836
USH2A	O75445-1.3	G262R	Pathogenic	0.716
USH2A	O75445-1.3	G262S	Pathogenic	0.769
USH2A	O75445-1.3	G262T	Pathogenic	0.911
USH2A	O75445-1.3	G262V	Pathogenic	0.962
USH2A	O75445-1.3	G262W	Pathogenic	0.743
USH2A	O75445-1.3	G262Y	Pathogenic	0.876
USH2A	O75445-1.3	L263A	Neutral	0.18
USH2A	O75445-1.3	L263C	Neutral	0.224
USH2A	O75445-1.3	L263D	Pathogenic	0.906
USH2A	O75445-1.3	L263E	Pathogenic	0.876
USH2A	O75445-1.3	L263F	Neutral	0.181
USH2A	O75445-1.3	L263G	Pathogenic	0.623
USH2A	O75445-1.3	L263H	Pathogenic	0.865
USH2A	O75445-1.3	L263I	Neutral	0.057
USH2A	O75445-1.3	L263K	Pathogenic	0.807
USH2A	O75445-1.3	L263M	Neutral	0.068
USH2A	O75445-1.3	L263N	Pathogenic	0.82
USH2A	O75445-1.3	L263P	Pathogenic	0.662
USH2A	O75445-1.3	L263Q	Pathogenic	0.747
USH2A	O75445-1.3	L263R	Pathogenic	0.735
USH2A	O75445-1.3	L263S	Neutral	0.419
USH2A	O75445-1.3	L263T	Neutral	0.342
USH2A	O75445-1.3	L263V	Neutral	0.083
USH2A	O75445-1.3	L263W	Neutral	0.37
USH2A	O75445-1.3	L263Y	Neutral	0.365
USH2A	O75445-1.3	E264A	Neutral	0.309
USH2A	O75445-1.3	E264C	Pathogenic	0.932
USH2A	O75445-1.3	E264D	Neutral	0.051
USH2A	O75445-1.3	E264F	Pathogenic	0.89
USH2A	O75445-1.3	E264G	Neutral	0.322
USH2A	O75445-1.3	E264H	Neutral	0.341
USH2A	O75445-1.3	E264I	Pathogenic	0.921
USH2A	O75445-1.3	E264K	Neutral	0.096
USH2A	O75445-1.3	E264L	Pathogenic	0.917
USH2A	O75445-1.3	E264M	Pathogenic	0.793
USH2A	O75445-1.3	E264N	Neutral	0.24
USH2A	O75445-1.3	E264P	Pathogenic	0.534
USH2A	O75445-1.3	E264Q	Neutral	0.087
USH2A	O75445-1.3	E264R	Neutral	0.139
USH2A	O75445-1.3	E264S	Neutral	0.167
USH2A	O75445-1.3	E264T	Pathogenic	0.501
USH2A	O75445-1.3	E264V	Pathogenic	0.844
USH2A	O75445-1.3	E264W	Pathogenic	0.806
USH2A	O75445-1.3	E264Y	Pathogenic	0.66
USH2A	O75445-1.3	Q265A	Pathogenic	0.862
USH2A	O75445-1.3	Q265C	Pathogenic	0.988
USH2A	O75445-1.3	Q265D	Pathogenic	0.857
USH2A	O75445-1.3	Q265E	Pathogenic	0.657
USH2A	O75445-1.3	Q265F	Pathogenic	0.994
USH2A	O75445-1.3	Q265G	Pathogenic	0.869
USH2A	O75445-1.3	Q265H	Pathogenic	0.909
USH2A	O75445-1.3	Q265I	Pathogenic	0.996
USH2A	O75445-1.3	Q265K	Pathogenic	0.757
USH2A	O75445-1.3	Q265L	Pathogenic	0.989
USH2A	O75445-1.3	Q265M	Pathogenic	0.934
USH2A	O75445-1.3	Q265N	Pathogenic	0.866
USH2A	O75445-1.3	Q265P	Pathogenic	0.941
USH2A	O75445-1.3	Q265R	Pathogenic	0.674
USH2A	O75445-1.3	Q265S	Pathogenic	0.736
USH2A	O75445-1.3	Q265T	Pathogenic	0.933
USH2A	O75445-1.3	Q265V	Pathogenic	0.987
USH2A	O75445-1.3	Q265W	Pathogenic	0.972
USH2A	O75445-1.3	Q265Y	Pathogenic	0.943
USH2A	O75445-1.3	F266A	Pathogenic	0.943
USH2A	O75445-1.3	F266C	Pathogenic	0.956
USH2A	O75445-1.3	F266D	Pathogenic	0.993
USH2A	O75445-1.3	F266E	Pathogenic	0.996
USH2A	O75445-1.3	F266G	Pathogenic	0.96
USH2A	O75445-1.3	F266H	Pathogenic	0.976
USH2A	O75445-1.3	F266I	Pathogenic	0.905
USH2A	O75445-1.3	F266K	Pathogenic	0.998
USH2A	O75445-1.3	F266L	Pathogenic	0.908
USH2A	O75445-1.3	F266M	Pathogenic	0.926
USH2A	O75445-1.3	F266N	Pathogenic	0.993
USH2A	O75445-1.3	F266P	Pathogenic	0.993
USH2A	O75445-1.3	F266Q	Pathogenic	0.996
USH2A	O75445-1.3	F266R	Pathogenic	0.998
USH2A	O75445-1.3	F266S	Pathogenic	0.96
USH2A	O75445-1.3	F266T	Pathogenic	0.975
USH2A	O75445-1.3	F266V	Pathogenic	0.94
USH2A	O75445-1.3	F266W	Pathogenic	0.751
USH2A	O75445-1.3	F266Y	Pathogenic	0.585
USH2A	O75445-1.3	V267A	Neutral	0.287
USH2A	O75445-1.3	V267C	Pathogenic	0.548
USH2A	O75445-1.3	V267D	Pathogenic	0.947
USH2A	O75445-1.3	V267E	Pathogenic	0.909
USH2A	O75445-1.3	V267F	Pathogenic	0.502
USH2A	O75445-1.3	V267G	Pathogenic	0.752
USH2A	O75445-1.3	V267H	Pathogenic	0.921
USH2A	O75445-1.3	V267I	Neutral	0.05
USH2A	O75445-1.3	V267K	Pathogenic	0.838
USH2A	O75445-1.3	V267L	Neutral	0.208
USH2A	O75445-1.3	V267M	Neutral	0.172
USH2A	O75445-1.3	V267N	Pathogenic	0.95
USH2A	O75445-1.3	V267P	Pathogenic	0.782
USH2A	O75445-1.3	V267Q	Pathogenic	0.874
USH2A	O75445-1.3	V267R	Pathogenic	0.887
USH2A	O75445-1.3	V267S	Pathogenic	0.752
USH2A	O75445-1.3	V267T	Neutral	0.488
USH2A	O75445-1.3	V267W	Pathogenic	0.729
USH2A	O75445-1.3	V267Y	Neutral	0.415
USH2A	O75445-1.3	G268A	Pathogenic	0.842
USH2A	O75445-1.3	G268C	Pathogenic	0.98
USH2A	O75445-1.3	G268D	Pathogenic	0.876
USH2A	O75445-1.3	G268E	Pathogenic	0.894
USH2A	O75445-1.3	G268F	Pathogenic	0.937
USH2A	O75445-1.3	G268H	Pathogenic	0.832
USH2A	O75445-1.3	G268I	Pathogenic	0.98
USH2A	O75445-1.3	G268K	Pathogenic	0.814
USH2A	O75445-1.3	G268L	Pathogenic	0.979
USH2A	O75445-1.3	G268M	Pathogenic	0.941
USH2A	O75445-1.3	G268N	Pathogenic	0.708
USH2A	O75445-1.3	G268P	Pathogenic	0.942
USH2A	O75445-1.3	G268Q	Pathogenic	0.854
USH2A	O75445-1.3	G268R	Pathogenic	0.744
USH2A	O75445-1.3	G268S	Pathogenic	0.793
USH2A	O75445-1.3	G268T	Pathogenic	0.921
USH2A	O75445-1.3	G268V	Pathogenic	0.967
USH2A	O75445-1.3	G268W	Pathogenic	0.769
USH2A	O75445-1.3	G268Y	Pathogenic	0.89
USH2A	O75445-1.3	R269A	Neutral	0.448
USH2A	O75445-1.3	R269C	Pathogenic	0.916
USH2A	O75445-1.3	R269D	Pathogenic	0.701
USH2A	O75445-1.3	R269E	Neutral	0.461
USH2A	O75445-1.3	R269F	Pathogenic	0.987
USH2A	O75445-1.3	R269G	Neutral	0.464
USH2A	O75445-1.3	R269H	Pathogenic	0.626
USH2A	O75445-1.3	R269I	Pathogenic	0.982
USH2A	O75445-1.3	R269K	Neutral	0.241
USH2A	O75445-1.3	R269L	Pathogenic	0.959
USH2A	O75445-1.3	R269M	Pathogenic	0.889
USH2A	O75445-1.3	R269N	Neutral	0.365
USH2A	O75445-1.3	R269P	Pathogenic	0.826
USH2A	O75445-1.3	R269Q	Neutral	0.351
USH2A	O75445-1.3	R269S	Neutral	0.453
USH2A	O75445-1.3	R269T	Pathogenic	0.646
USH2A	O75445-1.3	R269V	Pathogenic	0.958
USH2A	O75445-1.3	R269W	Pathogenic	0.989
USH2A	O75445-1.3	R269Y	Pathogenic	0.965
USH2A	O75445-1.3	M270A	Pathogenic	0.934
USH2A	O75445-1.3	M270C	Pathogenic	0.949
USH2A	O75445-1.3	M270D	Pathogenic	0.996
USH2A	O75445-1.3	M270E	Pathogenic	0.995
USH2A	O75445-1.3	M270F	Pathogenic	0.958
USH2A	O75445-1.3	M270G	Pathogenic	0.979
USH2A	O75445-1.3	M270H	Pathogenic	0.994
USH2A	O75445-1.3	M270I	Pathogenic	0.934
USH2A	O75445-1.3	M270K	Pathogenic	0.992
USH2A	O75445-1.3	M270L	Pathogenic	0.855
USH2A	O75445-1.3	M270N	Pathogenic	0.992
USH2A	O75445-1.3	M270P	Pathogenic	0.982
USH2A	O75445-1.3	M270Q	Pathogenic	0.973
USH2A	O75445-1.3	M270R	Pathogenic	0.987
USH2A	O75445-1.3	M270S	Pathogenic	0.953
USH2A	O75445-1.3	M270T	Pathogenic	0.971
USH2A	O75445-1.3	M270V	Pathogenic	0.854
USH2A	O75445-1.3	M270W	Pathogenic	0.963
USH2A	O75445-1.3	M270Y	Pathogenic	0.974
USH2A	O75445-1.3	Q271A	Pathogenic	0.858
USH2A	O75445-1.3	Q271C	Pathogenic	0.988
USH2A	O75445-1.3	Q271D	Pathogenic	0.853
USH2A	O75445-1.3	Q271E	Pathogenic	0.65
USH2A	O75445-1.3	Q271F	Pathogenic	0.993
USH2A	O75445-1.3	Q271G	Pathogenic	0.866
USH2A	O75445-1.3	Q271H	Pathogenic	0.906
USH2A	O75445-1.3	Q271I	Pathogenic	0.995
USH2A	O75445-1.3	Q271K	Pathogenic	0.751
USH2A	O75445-1.3	Q271L	Pathogenic	0.989
USH2A	O75445-1.3	Q271M	Pathogenic	0.932
USH2A	O75445-1.3	Q271N	Pathogenic	0.862
USH2A	O75445-1.3	Q271P	Pathogenic	0.939
USH2A	O75445-1.3	Q271R	Pathogenic	0.667
USH2A	O75445-1.3	Q271S	Pathogenic	0.73
USH2A	O75445-1.3	Q271T	Pathogenic	0.931
USH2A	O75445-1.3	Q271V	Pathogenic	0.987
USH2A	O75445-1.3	Q271W	Pathogenic	0.971
USH2A	O75445-1.3	Q271Y	Pathogenic	0.941
USH2A	O75445-1.3	D272A	Pathogenic	0.986
USH2A	O75445-1.3	D272C	Pathogenic	0.998
USH2A	O75445-1.3	D272E	Pathogenic	0.656
USH2A	O75445-1.3	D272F	Pathogenic	0.994
USH2A	O75445-1.3	D272G	Pathogenic	0.933
USH2A	O75445-1.3	D272H	Pathogenic	0.961
USH2A	O75445-1.3	D272I	Pathogenic	0.996
USH2A	O75445-1.3	D272K	Pathogenic	0.912
USH2A	O75445-1.3	D272L	Pathogenic	0.998
USH2A	O75445-1.3	D272M	Pathogenic	0.995
USH2A	O75445-1.3	D272N	Pathogenic	0.871
USH2A	O75445-1.3	D272P	Pathogenic	0.987
USH2A	O75445-1.3	D272Q	Pathogenic	0.913
USH2A	O75445-1.3	D272R	Pathogenic	0.94
USH2A	O75445-1.3	D272S	Pathogenic	0.931
USH2A	O75445-1.3	D272T	Pathogenic	0.983
USH2A	O75445-1.3	D272V	Pathogenic	0.997
USH2A	O75445-1.3	D272W	Pathogenic	0.995
USH2A	O75445-1.3	D272Y	Pathogenic	0.989
USH2A	O75445-1.3	F273A	Pathogenic	0.916
USH2A	O75445-1.3	F273C	Pathogenic	0.935
USH2A	O75445-1.3	F273D	Pathogenic	0.989
USH2A	O75445-1.3	F273E	Pathogenic	0.993
USH2A	O75445-1.3	F273G	Pathogenic	0.94
USH2A	O75445-1.3	F273H	Pathogenic	0.964
USH2A	O75445-1.3	F273I	Pathogenic	0.862
USH2A	O75445-1.3	F273K	Pathogenic	0.998
USH2A	O75445-1.3	F273L	Pathogenic	0.867
USH2A	O75445-1.3	F273M	Pathogenic	0.891
USH2A	O75445-1.3	F273N	Pathogenic	0.99
USH2A	O75445-1.3	F273P	Pathogenic	0.99
USH2A	O75445-1.3	F273Q	Pathogenic	0.993
USH2A	O75445-1.3	F273R	Pathogenic	0.996
USH2A	O75445-1.3	F273S	Pathogenic	0.94
USH2A	O75445-1.3	F273T	Pathogenic	0.963
USH2A	O75445-1.3	F273V	Pathogenic	0.911
USH2A	O75445-1.3	F273W	Pathogenic	0.665
USH2A	O75445-1.3	F273Y	Neutral	0.481
USH2A	O75445-1.3	R274A	Pathogenic	0.623
USH2A	O75445-1.3	R274C	Pathogenic	0.957
USH2A	O75445-1.3	R274D	Pathogenic	0.827
USH2A	O75445-1.3	R274E	Pathogenic	0.636
USH2A	O75445-1.3	R274F	Pathogenic	0.994
USH2A	O75445-1.3	R274G	Pathogenic	0.638
USH2A	O75445-1.3	R274H	Pathogenic	0.774
USH2A	O75445-1.3	R274I	Pathogenic	0.991
USH2A	O75445-1.3	R274K	Neutral	0.393
USH2A	O75445-1.3	R274L	Pathogenic	0.979
USH2A	O75445-1.3	R274M	Pathogenic	0.942
USH2A	O75445-1.3	R274N	Pathogenic	0.539
USH2A	O75445-1.3	R274P	Pathogenic	0.907
USH2A	O75445-1.3	R274Q	Pathogenic	0.525
USH2A	O75445-1.3	R274S	Pathogenic	0.628
USH2A	O75445-1.3	R274T	Pathogenic	0.788
USH2A	O75445-1.3	R274V	Pathogenic	0.979
USH2A	O75445-1.3	R274W	Pathogenic	0.995
USH2A	O75445-1.3	R274Y	Pathogenic	0.983
USH2A	O75445-1.3	L275A	Neutral	0.204
USH2A	O75445-1.3	L275C	Neutral	0.253
USH2A	O75445-1.3	L275D	Pathogenic	0.919
USH2A	O75445-1.3	L275E	Pathogenic	0.892
USH2A	O75445-1.3	L275F	Neutral	0.205
USH2A	O75445-1.3	L275G	Pathogenic	0.66
USH2A	O75445-1.3	L275H	Pathogenic	0.883
USH2A	O75445-1.3	L275I	Neutral	0.066
USH2A	O75445-1.3	L275K	Pathogenic	0.831
USH2A	O75445-1.3	L275M	Neutral	0.078
USH2A	O75445-1.3	L275N	Pathogenic	0.842
USH2A	O75445-1.3	L275P	Pathogenic	0.696
USH2A	O75445-1.3	L275Q	Pathogenic	0.775
USH2A	O75445-1.3	L275R	Pathogenic	0.765
USH2A	O75445-1.3	L275S	Neutral	0.458
USH2A	O75445-1.3	L275T	Neutral	0.378
USH2A	O75445-1.3	L275V	Neutral	0.096
USH2A	O75445-1.3	L275W	Neutral	0.408
USH2A	O75445-1.3	L275Y	Neutral	0.402
USH2A	O75445-1.3	Y276A	Pathogenic	0.916
USH2A	O75445-1.3	Y276C	Pathogenic	0.936
USH2A	O75445-1.3	Y276D	Pathogenic	0.989
USH2A	O75445-1.3	Y276E	Pathogenic	0.985
USH2A	O75445-1.3	Y276F	Pathogenic	0.63
USH2A	O75445-1.3	Y276G	Pathogenic	0.94
USH2A	O75445-1.3	Y276H	Pathogenic	0.693
USH2A	O75445-1.3	Y276I	Pathogenic	0.97
USH2A	O75445-1.3	Y276K	Pathogenic	0.995
USH2A	O75445-1.3	Y276L	Pathogenic	0.969
USH2A	O75445-1.3	Y276M	Pathogenic	0.961
USH2A	O75445-1.3	Y276N	Pathogenic	0.978
USH2A	O75445-1.3	Y276P	Pathogenic	0.977
USH2A	O75445-1.3	Y276Q	Pathogenic	0.966
USH2A	O75445-1.3	Y276R	Pathogenic	0.994
USH2A	O75445-1.3	Y276S	Pathogenic	0.94
USH2A	O75445-1.3	Y276T	Pathogenic	0.963
USH2A	O75445-1.3	Y276V	Pathogenic	0.93
USH2A	O75445-1.3	Y276W	Pathogenic	0.745
USH2A	O75445-1.3	Q277A	Neutral	0.124
USH2A	O75445-1.3	Q277C	Pathogenic	0.655
USH2A	O75445-1.3	Q277D	Neutral	0.119
USH2A	O75445-1.3	Q277E	Neutral	0.042
USH2A	O75445-1.3	Q277F	Pathogenic	0.78
USH2A	O75445-1.3	Q277G	Neutral	0.131
USH2A	O75445-1.3	Q277H	Neutral	0.184
USH2A	O75445-1.3	Q277I	Pathogenic	0.836
USH2A	O75445-1.3	Q277K	Neutral	0.066
USH2A	O75445-1.3	Q277L	Pathogenic	0.679
USH2A	O75445-1.3	Q277M	Neutral	0.244
USH2A	O75445-1.3	Q277N	Neutral	0.128
USH2A	O75445-1.3	Q277P	Neutral	0.267
USH2A	O75445-1.3	Q277R	Neutral	0.045
USH2A	O75445-1.3	Q277S	Neutral	0.06
USH2A	O75445-1.3	Q277T	Neutral	0.241
USH2A	O75445-1.3	Q277V	Pathogenic	0.633
USH2A	O75445-1.3	Q277W	Neutral	0.443
USH2A	O75445-1.3	Q277Y	Neutral	0.271
USH2A	O75445-1.3	V278A	Neutral	0.13
USH2A	O75445-1.3	V278C	Neutral	0.31
USH2A	O75445-1.3	V278D	Pathogenic	0.868
USH2A	O75445-1.3	V278E	Pathogenic	0.788
USH2A	O75445-1.3	V278F	Neutral	0.271
USH2A	O75445-1.3	V278G	Pathogenic	0.529
USH2A	O75445-1.3	V278H	Pathogenic	0.812
USH2A	O75445-1.3	V278I	Neutral	0.019
USH2A	O75445-1.3	V278K	Pathogenic	0.657
USH2A	O75445-1.3	V278L	Neutral	0.089
USH2A	O75445-1.3	V278M	Neutral	0.072
USH2A	O75445-1.3	V278N	Pathogenic	0.876
USH2A	O75445-1.3	V278P	Pathogenic	0.571
USH2A	O75445-1.3	V278Q	Pathogenic	0.72
USH2A	O75445-1.3	V278R	Pathogenic	0.744
USH2A	O75445-1.3	V278S	Pathogenic	0.528
USH2A	O75445-1.3	V278T	Neutral	0.261
USH2A	O75445-1.3	V278W	Neutral	0.499
USH2A	O75445-1.3	V278Y	Neutral	0.208
USH2A	O75445-1.3	A279C	Neutral	0.323
USH2A	O75445-1.3	A279D	Pathogenic	0.721
USH2A	O75445-1.3	A279E	Neutral	0.373
USH2A	O75445-1.3	A279F	Neutral	0.435
USH2A	O75445-1.3	A279G	Neutral	0.285
USH2A	O75445-1.3	A279H	Neutral	0.41
USH2A	O75445-1.3	A279I	Neutral	0.326
USH2A	O75445-1.3	A279K	Neutral	0.235
USH2A	O75445-1.3	A279L	Neutral	0.315
USH2A	O75445-1.3	A279M	Neutral	0.267
USH2A	O75445-1.3	A279N	Pathogenic	0.67
USH2A	O75445-1.3	A279P	Neutral	0.457
USH2A	O75445-1.3	A279Q	Neutral	0.292
USH2A	O75445-1.3	A279R	Neutral	0.17
USH2A	O75445-1.3	A279S	Neutral	0.212
USH2A	O75445-1.3	A279T	Neutral	0.218
USH2A	O75445-1.3	A279V	Neutral	0.226
USH2A	O75445-1.3	A279W	Neutral	0.474
USH2A	O75445-1.3	A279Y	Neutral	0.296
USH2A	O75445-1.3	L280A	Pathogenic	0.824
USH2A	O75445-1.3	L280C	Pathogenic	0.86
USH2A	O75445-1.3	L280D	Pathogenic	0.995
USH2A	O75445-1.3	L280E	Pathogenic	0.993
USH2A	O75445-1.3	L280F	Pathogenic	0.824
USH2A	O75445-1.3	L280G	Pathogenic	0.972
USH2A	O75445-1.3	L280H	Pathogenic	0.993
USH2A	O75445-1.3	L280I	Pathogenic	0.564
USH2A	O75445-1.3	L280K	Pathogenic	0.989
USH2A	O75445-1.3	L280M	Pathogenic	0.608
USH2A	O75445-1.3	L280N	Pathogenic	0.99
USH2A	O75445-1.3	L280P	Pathogenic	0.977
USH2A	O75445-1.3	L280Q	Pathogenic	0.984
USH2A	O75445-1.3	L280R	Pathogenic	0.983
USH2A	O75445-1.3	L280S	Pathogenic	0.939
USH2A	O75445-1.3	L280T	Pathogenic	0.917
USH2A	O75445-1.3	L280V	Pathogenic	0.659
USH2A	O75445-1.3	L280W	Pathogenic	0.926
USH2A	O75445-1.3	L280Y	Pathogenic	0.924
USH2A	O75445-1.3	T281A	Neutral	0.434
USH2A	O75445-1.3	T281C	Pathogenic	0.818
USH2A	O75445-1.3	T281D	Pathogenic	0.86
USH2A	O75445-1.3	T281E	Pathogenic	0.786
USH2A	O75445-1.3	T281F	Pathogenic	0.833
USH2A	O75445-1.3	T281G	Pathogenic	0.706
USH2A	O75445-1.3	T281H	Pathogenic	0.811
USH2A	O75445-1.3	T281I	Pathogenic	0.758
USH2A	O75445-1.3	T281K	Pathogenic	0.655
USH2A	O75445-1.3	T281L	Pathogenic	0.748
USH2A	O75445-1.3	T281M	Pathogenic	0.702
USH2A	O75445-1.3	T281N	Pathogenic	0.705
USH2A	O75445-1.3	T281P	Pathogenic	0.818
USH2A	O75445-1.3	T281Q	Pathogenic	0.717
USH2A	O75445-1.3	T281R	Pathogenic	0.557
USH2A	O75445-1.3	T281S	Neutral	0.314
USH2A	O75445-1.3	T281V	Pathogenic	0.654
USH2A	O75445-1.3	T281W	Pathogenic	0.718
USH2A	O75445-1.3	T281Y	Pathogenic	0.732
USH2A	O75445-1.3	N282A	Pathogenic	0.971
USH2A	O75445-1.3	N282C	Pathogenic	0.995
USH2A	O75445-1.3	N282D	Pathogenic	0.807
USH2A	O75445-1.3	N282E	Pathogenic	0.873
USH2A	O75445-1.3	N282F	Pathogenic	0.991
USH2A	O75445-1.3	N282G	Pathogenic	0.748
USH2A	O75445-1.3	N282H	Pathogenic	0.762
USH2A	O75445-1.3	N282I	Pathogenic	0.994
USH2A	O75445-1.3	N282K	Pathogenic	0.781
USH2A	O75445-1.3	N282L	Pathogenic	0.994
USH2A	O75445-1.3	N282M	Pathogenic	0.982
USH2A	O75445-1.3	N282P	Pathogenic	0.988
USH2A	O75445-1.3	N282Q	Pathogenic	0.875
USH2A	O75445-1.3	N282R	Pathogenic	0.703
USH2A	O75445-1.3	N282S	Pathogenic	0.74
USH2A	O75445-1.3	N282T	Pathogenic	0.935
USH2A	O75445-1.3	N282V	Pathogenic	0.996
USH2A	O75445-1.3	N282W	Pathogenic	0.993
USH2A	O75445-1.3	N282Y	Pathogenic	0.965
USH2A	O75445-1.3	R283A	Pathogenic	0.878
USH2A	O75445-1.3	R283C	Pathogenic	0.99
USH2A	O75445-1.3	R283D	Pathogenic	0.954
USH2A	O75445-1.3	R283E	Pathogenic	0.883
USH2A	O75445-1.3	R283F	Pathogenic	0.999
USH2A	O75445-1.3	R283G	Pathogenic	0.884
USH2A	O75445-1.3	R283H	Pathogenic	0.937
USH2A	O75445-1.3	R283I	Pathogenic	0.998
USH2A	O75445-1.3	R283K	Pathogenic	0.737
USH2A	O75445-1.3	R283L	Pathogenic	0.995
USH2A	O75445-1.3	R283M	Pathogenic	0.986
USH2A	O75445-1.3	R283N	Pathogenic	0.835
USH2A	O75445-1.3	R283P	Pathogenic	0.977
USH2A	O75445-1.3	R283Q	Pathogenic	0.827
USH2A	O75445-1.3	R283S	Pathogenic	0.88
USH2A	O75445-1.3	R283T	Pathogenic	0.942
USH2A	O75445-1.3	R283V	Pathogenic	0.995
USH2A	O75445-1.3	R283W	Pathogenic	0.999
USH2A	O75445-1.3	R283Y	Pathogenic	0.996
USH2A	O75445-1.3	E284A	Pathogenic	0.667
USH2A	O75445-1.3	E284C	Pathogenic	0.984
USH2A	O75445-1.3	E284D	Neutral	0.195
USH2A	O75445-1.3	E284F	Pathogenic	0.973
USH2A	O75445-1.3	E284G	Pathogenic	0.681
USH2A	O75445-1.3	E284H	Pathogenic	0.699
USH2A	O75445-1.3	E284I	Pathogenic	0.981
USH2A	O75445-1.3	E284K	Neutral	0.324
USH2A	O75445-1.3	E284L	Pathogenic	0.98
USH2A	O75445-1.3	E284M	Pathogenic	0.945
USH2A	O75445-1.3	E284N	Pathogenic	0.587
USH2A	O75445-1.3	E284P	Pathogenic	0.837
USH2A	O75445-1.3	E284Q	Neutral	0.298
USH2A	O75445-1.3	E284R	Neutral	0.42
USH2A	O75445-1.3	E284S	Neutral	0.473
USH2A	O75445-1.3	E284T	Pathogenic	0.818
USH2A	O75445-1.3	E284V	Pathogenic	0.961
USH2A	O75445-1.3	E284W	Pathogenic	0.949
USH2A	O75445-1.3	E284Y	Pathogenic	0.897
USH2A	O75445-1.3	I285A	Pathogenic	0.689
USH2A	O75445-1.3	I285C	Pathogenic	0.744
USH2A	O75445-1.3	I285D	Pathogenic	0.977
USH2A	O75445-1.3	I285E	Pathogenic	0.986
USH2A	O75445-1.3	I285F	Pathogenic	0.67
USH2A	O75445-1.3	I285G	Pathogenic	0.943
USH2A	O75445-1.3	I285H	Pathogenic	0.985
USH2A	O75445-1.3	I285K	Pathogenic	0.99
USH2A	O75445-1.3	I285L	Neutral	0.367
USH2A	O75445-1.3	I285M	Pathogenic	0.626
USH2A	O75445-1.3	I285N	Pathogenic	0.979
USH2A	O75445-1.3	I285P	Pathogenic	0.952
USH2A	O75445-1.3	I285Q	Pathogenic	0.985
USH2A	O75445-1.3	I285R	Pathogenic	0.985
USH2A	O75445-1.3	I285S	Pathogenic	0.879
USH2A	O75445-1.3	I285T	Pathogenic	0.84
USH2A	O75445-1.3	I285V	Neutral	0.149
USH2A	O75445-1.3	I285W	Pathogenic	0.924
USH2A	O75445-1.3	I285Y	Pathogenic	0.853
USH2A	O75445-1.3	L286A	Neutral	0.053
USH2A	O75445-1.3	L286C	Neutral	0.069
USH2A	O75445-1.3	L286D	Pathogenic	0.712
USH2A	O75445-1.3	L286E	Pathogenic	0.644
USH2A	O75445-1.3	L286F	Neutral	0.053
USH2A	O75445-1.3	L286G	Neutral	0.298
USH2A	O75445-1.3	L286H	Pathogenic	0.622
USH2A	O75445-1.3	L286I	Neutral	0.015
USH2A	O75445-1.3	L286K	Pathogenic	0.518
USH2A	O75445-1.3	L286M	Neutral	0.018
USH2A	O75445-1.3	L286N	Pathogenic	0.539
USH2A	O75445-1.3	L286P	Neutral	0.334
USH2A	O75445-1.3	L286Q	Neutral	0.431
USH2A	O75445-1.3	L286R	Neutral	0.416
USH2A	O75445-1.3	L286S	Neutral	0.156
USH2A	O75445-1.3	L286T	Neutral	0.118
USH2A	O75445-1.3	L286V	Neutral	0.023
USH2A	O75445-1.3	L286W	Neutral	0.131
USH2A	O75445-1.3	L286Y	Neutral	0.128
USH2A	O75445-1.3	E287A	Pathogenic	0.745
USH2A	O75445-1.3	E287C	Pathogenic	0.989
USH2A	O75445-1.3	E287D	Neutral	0.261
USH2A	O75445-1.3	E287F	Pathogenic	0.982
USH2A	O75445-1.3	E287G	Pathogenic	0.757
USH2A	O75445-1.3	E287H	Pathogenic	0.772
USH2A	O75445-1.3	E287I	Pathogenic	0.987
USH2A	O75445-1.3	E287K	Neutral	0.411
USH2A	O75445-1.3	E287L	Pathogenic	0.986
USH2A	O75445-1.3	E287M	Pathogenic	0.962
USH2A	O75445-1.3	E287N	Pathogenic	0.674
USH2A	O75445-1.3	E287P	Pathogenic	0.882
USH2A	O75445-1.3	E287Q	Neutral	0.382
USH2A	O75445-1.3	E287R	Pathogenic	0.514
USH2A	O75445-1.3	E287S	Pathogenic	0.566
USH2A	O75445-1.3	E287T	Pathogenic	0.868
USH2A	O75445-1.3	E287V	Pathogenic	0.973
USH2A	O75445-1.3	E287W	Pathogenic	0.965
USH2A	O75445-1.3	E287Y	Pathogenic	0.927
USH2A	O75445-1.3	V288A	Neutral	0.213
USH2A	O75445-1.3	V288C	Neutral	0.448
USH2A	O75445-1.3	V288D	Pathogenic	0.922
USH2A	O75445-1.3	V288E	Pathogenic	0.87
USH2A	O75445-1.3	V288F	Neutral	0.403
USH2A	O75445-1.3	V288G	Pathogenic	0.671
USH2A	O75445-1.3	V288H	Pathogenic	0.887
USH2A	O75445-1.3	V288I	Neutral	0.034
USH2A	O75445-1.3	V288K	Pathogenic	0.776
USH2A	O75445-1.3	V288L	Neutral	0.15
USH2A	O75445-1.3	V288M	Neutral	0.123
USH2A	O75445-1.3	V288N	Pathogenic	0.928
USH2A	O75445-1.3	V288P	Pathogenic	0.706
USH2A	O75445-1.3	V288Q	Pathogenic	0.823
USH2A	O75445-1.3	V288R	Pathogenic	0.84
USH2A	O75445-1.3	V288S	Pathogenic	0.67
USH2A	O75445-1.3	V288T	Neutral	0.39
USH2A	O75445-1.3	V288W	Pathogenic	0.643
USH2A	O75445-1.3	V288Y	Neutral	0.323
USH2A	O75445-1.3	F289A	Neutral	0.399
USH2A	O75445-1.3	F289C	Neutral	0.466
USH2A	O75445-1.3	F289D	Pathogenic	0.848
USH2A	O75445-1.3	F289E	Pathogenic	0.903
USH2A	O75445-1.3	F289G	Neutral	0.489
USH2A	O75445-1.3	F289H	Pathogenic	0.62
USH2A	O75445-1.3	F289I	Neutral	0.277
USH2A	O75445-1.3	F289K	Pathogenic	0.962
USH2A	O75445-1.3	F289L	Neutral	0.284
USH2A	O75445-1.3	F289M	Neutral	0.334
USH2A	O75445-1.3	F289N	Pathogenic	0.858
USH2A	O75445-1.3	F289P	Pathogenic	0.855
USH2A	O75445-1.3	F289Q	Pathogenic	0.899
USH2A	O75445-1.3	F289R	Pathogenic	0.944
USH2A	O75445-1.3	F289S	Neutral	0.488
USH2A	O75445-1.3	F289T	Pathogenic	0.61
USH2A	O75445-1.3	F289V	Neutral	0.385
USH2A	O75445-1.3	F289W	Neutral	0.108
USH2A	O75445-1.3	F289Y	Neutral	0.053
USH2A	O75445-1.3	S290A	Neutral	0.392
USH2A	O75445-1.3	S290C	Pathogenic	0.79
USH2A	O75445-1.3	S290D	Pathogenic	0.548
USH2A	O75445-1.3	S290E	Neutral	0.39
USH2A	O75445-1.3	S290F	Pathogenic	0.726
USH2A	O75445-1.3	S290G	Neutral	0.407
USH2A	O75445-1.3	S290H	Neutral	0.468
USH2A	O75445-1.3	S290I	Pathogenic	0.792
USH2A	O75445-1.3	S290K	Neutral	0.248
USH2A	O75445-1.3	S290L	Pathogenic	0.783
USH2A	O75445-1.3	S290M	Pathogenic	0.556
USH2A	O75445-1.3	S290N	Neutral	0.294
USH2A	O75445-1.3	S290P	Pathogenic	0.743
USH2A	O75445-1.3	S290Q	Neutral	0.306
USH2A	O75445-1.3	S290R	Neutral	0.333
USH2A	O75445-1.3	S290T	Neutral	0.286
USH2A	O75445-1.3	S290V	Pathogenic	0.84
USH2A	O75445-1.3	S290W	Pathogenic	0.756
USH2A	O75445-1.3	S290Y	Pathogenic	0.592
USH2A	O75445-1.3	G291A	Pathogenic	0.771
USH2A	O75445-1.3	G291C	Pathogenic	0.968
USH2A	O75445-1.3	G291D	Pathogenic	0.817
USH2A	O75445-1.3	G291E	Pathogenic	0.843
USH2A	O75445-1.3	G291F	Pathogenic	0.904
USH2A	O75445-1.3	G291H	Pathogenic	0.757
USH2A	O75445-1.3	G291I	Pathogenic	0.969
USH2A	O75445-1.3	G291K	Pathogenic	0.735
USH2A	O75445-1.3	G291L	Pathogenic	0.967
USH2A	O75445-1.3	G291M	Pathogenic	0.91
USH2A	O75445-1.3	G291N	Pathogenic	0.605
USH2A	O75445-1.3	G291P	Pathogenic	0.911
USH2A	O75445-1.3	G291Q	Pathogenic	0.788
USH2A	O75445-1.3	G291R	Pathogenic	0.648
USH2A	O75445-1.3	G291S	Pathogenic	0.708
USH2A	O75445-1.3	G291T	Pathogenic	0.881
USH2A	O75445-1.3	G291V	Pathogenic	0.949
USH2A	O75445-1.3	G291W	Pathogenic	0.678
USH2A	O75445-1.3	G291Y	Pathogenic	0.837
USH2A	O75445-1.3	D292A	Neutral	0.049
USH2A	O75445-1.3	D292C	Neutral	0.234
USH2A	O75445-1.3	D292E	Neutral	0.001
USH2A	O75445-1.3	D292F	Neutral	0.115
USH2A	O75445-1.3	D292G	Neutral	0.011
USH2A	O75445-1.3	D292H	Neutral	0.019
USH2A	O75445-1.3	D292I	Neutral	0.158
USH2A	O75445-1.3	D292K	Neutral	0.008
USH2A	O75445-1.3	D292L	Neutral	0.289
USH2A	O75445-1.3	D292M	Neutral	0.123
USH2A	O75445-1.3	D292N	Neutral	0.005
USH2A	O75445-1.3	D292P	Neutral	0.055
USH2A	O75445-1.3	D292Q	Neutral	0.008
USH2A	O75445-1.3	D292R	Neutral	0.012
USH2A	O75445-1.3	D292S	Neutral	0.01
USH2A	O75445-1.3	D292T	Neutral	0.043
USH2A	O75445-1.3	D292V	Neutral	0.205
USH2A	O75445-1.3	D292W	Neutral	0.132
USH2A	O75445-1.3	D292Y	Neutral	0.067
USH2A	O75445-1.3	L293A	Neutral	0.335
USH2A	O75445-1.3	L293C	Neutral	0.399
USH2A	O75445-1.3	L293D	Pathogenic	0.957
USH2A	O75445-1.3	L293E	Pathogenic	0.942
USH2A	O75445-1.3	L293F	Neutral	0.336
USH2A	O75445-1.3	L293G	Pathogenic	0.792
USH2A	O75445-1.3	L293H	Pathogenic	0.937
USH2A	O75445-1.3	L293I	Neutral	0.122
USH2A	O75445-1.3	L293K	Pathogenic	0.906
USH2A	O75445-1.3	L293M	Neutral	0.143
USH2A	O75445-1.3	L293N	Pathogenic	0.913
USH2A	O75445-1.3	L293P	Pathogenic	0.818
USH2A	O75445-1.3	L293Q	Pathogenic	0.871
USH2A	O75445-1.3	L293R	Pathogenic	0.865
USH2A	O75445-1.3	L293S	Pathogenic	0.624
USH2A	O75445-1.3	L293T	Pathogenic	0.544
USH2A	O75445-1.3	L293V	Neutral	0.173
USH2A	O75445-1.3	L293W	Pathogenic	0.575
USH2A	O75445-1.3	L293Y	Pathogenic	0.569
USH2A	O75445-1.3	L294A	Neutral	0.14
USH2A	O75445-1.3	L294C	Neutral	0.177
USH2A	O75445-1.3	L294D	Pathogenic	0.878
USH2A	O75445-1.3	L294E	Pathogenic	0.84
USH2A	O75445-1.3	L294F	Neutral	0.141
USH2A	O75445-1.3	L294G	Pathogenic	0.552
USH2A	O75445-1.3	L294H	Pathogenic	0.827
USH2A	O75445-1.3	L294I	Neutral	0.043
USH2A	O75445-1.3	L294K	Pathogenic	0.757
USH2A	O75445-1.3	L294M	Neutral	0.051
USH2A	O75445-1.3	L294N	Pathogenic	0.773
USH2A	O75445-1.3	L294P	Pathogenic	0.593
USH2A	O75445-1.3	L294Q	Pathogenic	0.687
USH2A	O75445-1.3	L294R	Pathogenic	0.674
USH2A	O75445-1.3	L294S	Neutral	0.349
USH2A	O75445-1.3	L294T	Neutral	0.279
USH2A	O75445-1.3	L294V	Neutral	0.063
USH2A	O75445-1.3	L294W	Neutral	0.304
USH2A	O75445-1.3	L294Y	Neutral	0.299
USH2A	O75445-1.3	R295A	Neutral	0.008
USH2A	O75445-1.3	R295C	Neutral	0.098
USH2A	O75445-1.3	R295D	Neutral	0.023
USH2A	O75445-1.3	R295E	Neutral	0.008
USH2A	O75445-1.3	R295F	Neutral	0.438
USH2A	O75445-1.3	R295G	Neutral	0.009
USH2A	O75445-1.3	R295H	Neutral	0.016
USH2A	O75445-1.3	R295I	Neutral	0.355
USH2A	O75445-1.3	R295K	Neutral	0.003
USH2A	O75445-1.3	R295L	Neutral	0.187
USH2A	O75445-1.3	R295M	Neutral	0.074
USH2A	O75445-1.3	R295N	Neutral	0.006
USH2A	O75445-1.3	R295P	Neutral	0.045
USH2A	O75445-1.3	R295Q	Neutral	0.005
USH2A	O75445-1.3	R295S	Neutral	0.008
USH2A	O75445-1.3	R295T	Neutral	0.018
USH2A	O75445-1.3	R295V	Neutral	0.183
USH2A	O75445-1.3	R295W	Neutral	0.479
USH2A	O75445-1.3	R295Y	Neutral	0.215
USH2A	O75445-1.3	L296A	Pathogenic	0.71
USH2A	O75445-1.3	L296C	Pathogenic	0.764
USH2A	O75445-1.3	L296D	Pathogenic	0.991
USH2A	O75445-1.3	L296E	Pathogenic	0.987
USH2A	O75445-1.3	L296F	Pathogenic	0.711
USH2A	O75445-1.3	L296G	Pathogenic	0.949
USH2A	O75445-1.3	L296H	Pathogenic	0.986
USH2A	O75445-1.3	L296I	Neutral	0.404
USH2A	O75445-1.3	L296K	Pathogenic	0.979
USH2A	O75445-1.3	L296M	Neutral	0.448
USH2A	O75445-1.3	L296N	Pathogenic	0.981
USH2A	O75445-1.3	L296P	Pathogenic	0.956
USH2A	O75445-1.3	L296Q	Pathogenic	0.971
USH2A	O75445-1.3	L296R	Pathogenic	0.969
USH2A	O75445-1.3	L296S	Pathogenic	0.89
USH2A	O75445-1.3	L296T	Pathogenic	0.853
USH2A	O75445-1.3	L296V	Pathogenic	0.504
USH2A	O75445-1.3	L296W	Pathogenic	0.868
USH2A	O75445-1.3	L296Y	Pathogenic	0.865
USH2A	O75445-1.3	H297A	Pathogenic	0.969
USH2A	O75445-1.3	H297C	Pathogenic	0.995
USH2A	O75445-1.3	H297D	Pathogenic	0.977
USH2A	O75445-1.3	H297E	Pathogenic	0.969
USH2A	O75445-1.3	H297F	Pathogenic	0.989
USH2A	O75445-1.3	H297G	Pathogenic	0.944
USH2A	O75445-1.3	H297I	Pathogenic	0.998
USH2A	O75445-1.3	H297K	Pathogenic	0.985
USH2A	O75445-1.3	H297L	Pathogenic	0.998
USH2A	O75445-1.3	H297M	Pathogenic	0.995
USH2A	O75445-1.3	H297N	Pathogenic	0.899
USH2A	O75445-1.3	H297P	Pathogenic	0.988
USH2A	O75445-1.3	H297Q	Pathogenic	0.968
USH2A	O75445-1.3	H297R	Pathogenic	0.95
USH2A	O75445-1.3	H297S	Pathogenic	0.944
USH2A	O75445-1.3	H297T	Pathogenic	0.986
USH2A	O75445-1.3	H297V	Pathogenic	0.997
USH2A	O75445-1.3	H297W	Pathogenic	0.99
USH2A	O75445-1.3	H297Y	Pathogenic	0.798
USH2A	O75445-1.3	A298C	Neutral	0.013
USH2A	O75445-1.3	A298D	Neutral	0.069
USH2A	O75445-1.3	A298E	Neutral	0.017
USH2A	O75445-1.3	A298F	Neutral	0.021
USH2A	O75445-1.3	A298G	Neutral	0.011
USH2A	O75445-1.3	A298H	Neutral	0.019
USH2A	O75445-1.3	A298I	Neutral	0.014
USH2A	O75445-1.3	A298K	Neutral	0.009
USH2A	O75445-1.3	A298L	Neutral	0.013
USH2A	O75445-1.3	A298M	Neutral	0.01
USH2A	O75445-1.3	A298N	Neutral	0.055
USH2A	O75445-1.3	A298P	Neutral	0.023
USH2A	O75445-1.3	A298Q	Neutral	0.012
USH2A	O75445-1.3	A298R	Neutral	0.006
USH2A	O75445-1.3	A298S	Neutral	0.008
USH2A	O75445-1.3	A298T	Neutral	0.008
USH2A	O75445-1.3	A298V	Neutral	0.008
USH2A	O75445-1.3	A298W	Neutral	0.025
USH2A	O75445-1.3	A298Y	Neutral	0.012
USH2A	O75445-1.3	Q299A	Pathogenic	0.912
USH2A	O75445-1.3	Q299C	Pathogenic	0.993
USH2A	O75445-1.3	Q299D	Pathogenic	0.908
USH2A	O75445-1.3	Q299E	Pathogenic	0.759
USH2A	O75445-1.3	Q299F	Pathogenic	0.996
USH2A	O75445-1.3	Q299G	Pathogenic	0.916
USH2A	O75445-1.3	Q299H	Pathogenic	0.943
USH2A	O75445-1.3	Q299I	Pathogenic	0.997
USH2A	O75445-1.3	Q299K	Pathogenic	0.837
USH2A	O75445-1.3	Q299L	Pathogenic	0.994
USH2A	O75445-1.3	Q299M	Pathogenic	0.959
USH2A	O75445-1.3	Q299N	Pathogenic	0.914
USH2A	O75445-1.3	Q299P	Pathogenic	0.964
USH2A	O75445-1.3	Q299R	Pathogenic	0.773
USH2A	O75445-1.3	Q299S	Pathogenic	0.822
USH2A	O75445-1.3	Q299T	Pathogenic	0.959
USH2A	O75445-1.3	Q299V	Pathogenic	0.992
USH2A	O75445-1.3	Q299W	Pathogenic	0.983
USH2A	O75445-1.3	Q299Y	Pathogenic	0.964
USH2A	O75445-1.3	S300A	Neutral	0.235
USH2A	O75445-1.3	S300C	Pathogenic	0.642
USH2A	O75445-1.3	S300D	Neutral	0.367
USH2A	O75445-1.3	S300E	Neutral	0.233
USH2A	O75445-1.3	S300F	Pathogenic	0.558
USH2A	O75445-1.3	S300G	Neutral	0.247
USH2A	O75445-1.3	S300H	Neutral	0.296
USH2A	O75445-1.3	S300I	Pathogenic	0.645
USH2A	O75445-1.3	S300K	Neutral	0.136
USH2A	O75445-1.3	S300L	Pathogenic	0.633
USH2A	O75445-1.3	S300M	Neutral	0.374
USH2A	O75445-1.3	S300N	Neutral	0.166
USH2A	O75445-1.3	S300P	Pathogenic	0.58
USH2A	O75445-1.3	S300Q	Neutral	0.174
USH2A	O75445-1.3	S300R	Neutral	0.192
USH2A	O75445-1.3	S300T	Neutral	0.16
USH2A	O75445-1.3	S300V	Pathogenic	0.714
USH2A	O75445-1.3	S300W	Pathogenic	0.596
USH2A	O75445-1.3	S300Y	Neutral	0.409
USH2A	O75445-1.3	H301A	Neutral	0.292
USH2A	O75445-1.3	H301C	Pathogenic	0.708
USH2A	O75445-1.3	H301D	Neutral	0.359
USH2A	O75445-1.3	H301E	Neutral	0.29
USH2A	O75445-1.3	H301F	Pathogenic	0.529
USH2A	O75445-1.3	H301G	Neutral	0.18
USH2A	O75445-1.3	H301I	Pathogenic	0.894
USH2A	O75445-1.3	H301K	Neutral	0.462
USH2A	O75445-1.3	H301L	Pathogenic	0.889
USH2A	O75445-1.3	H301M	Pathogenic	0.735
USH2A	O75445-1.3	H301N	Neutral	0.104
USH2A	O75445-1.3	H301P	Pathogenic	0.514
USH2A	O75445-1.3	H301Q	Neutral	0.281
USH2A	O75445-1.3	H301R	Neutral	0.2
USH2A	O75445-1.3	H301S	Neutral	0.179
USH2A	O75445-1.3	H301T	Neutral	0.481
USH2A	O75445-1.3	H301V	Pathogenic	0.834
USH2A	O75445-1.3	H301W	Pathogenic	0.567
USH2A	O75445-1.3	H301Y	Neutral	0.049
USH2A	O75445-1.3	C302A	Pathogenic	0.952
USH2A	O75445-1.3	C302D	Pathogenic	0.998
USH2A	O75445-1.3	C302E	Pathogenic	0.999
USH2A	O75445-1.3	C302F	Pathogenic	0.977
USH2A	O75445-1.3	C302G	Pathogenic	0.993
USH2A	O75445-1.3	C302H	Pathogenic	0.994
USH2A	O75445-1.3	C302I	Pathogenic	0.963
USH2A	O75445-1.3	C302K	Pathogenic	0.994
USH2A	O75445-1.3	C302L	Pathogenic	0.961
USH2A	O75445-1.3	C302M	Pathogenic	0.952
USH2A	O75445-1.3	C302N	Pathogenic	0.998
USH2A	O75445-1.3	C302P	Pathogenic	0.997
USH2A	O75445-1.3	C302Q	Pathogenic	0.996
USH2A	O75445-1.3	C302R	Pathogenic	0.991
USH2A	O75445-1.3	C302S	Pathogenic	0.985
USH2A	O75445-1.3	C302T	Pathogenic	0.985
USH2A	O75445-1.3	C302V	Pathogenic	0.973
USH2A	O75445-1.3	C302W	Pathogenic	0.955
USH2A	O75445-1.3	C302Y	Pathogenic	0.959
USH2A	O75445-1.3	R303A	Pathogenic	0.727
USH2A	O75445-1.3	R303C	Pathogenic	0.973
USH2A	O75445-1.3	R303D	Pathogenic	0.885
USH2A	O75445-1.3	R303E	Pathogenic	0.738
USH2A	O75445-1.3	R303F	Pathogenic	0.996
USH2A	O75445-1.3	R303G	Pathogenic	0.74
USH2A	O75445-1.3	R303H	Pathogenic	0.846
USH2A	O75445-1.3	R303I	Pathogenic	0.995
USH2A	O75445-1.3	R303K	Pathogenic	0.511
USH2A	O75445-1.3	R303L	Pathogenic	0.987
USH2A	O75445-1.3	R303M	Pathogenic	0.963
USH2A	O75445-1.3	R303N	Pathogenic	0.654
USH2A	O75445-1.3	R303P	Pathogenic	0.94
USH2A	O75445-1.3	R303Q	Pathogenic	0.64
USH2A	O75445-1.3	R303S	Pathogenic	0.732
USH2A	O75445-1.3	R303T	Pathogenic	0.857
USH2A	O75445-1.3	R303V	Pathogenic	0.987
USH2A	O75445-1.3	R303W	Pathogenic	0.997
USH2A	O75445-1.3	R303Y	Pathogenic	0.989
USH2A	O75445-1.3	C304A	Pathogenic	0.952
USH2A	O75445-1.3	C304D	Pathogenic	0.998
USH2A	O75445-1.3	C304E	Pathogenic	0.999
USH2A	O75445-1.3	C304F	Pathogenic	0.977
USH2A	O75445-1.3	C304G	Pathogenic	0.993
USH2A	O75445-1.3	C304H	Pathogenic	0.994
USH2A	O75445-1.3	C304I	Pathogenic	0.963
USH2A	O75445-1.3	C304K	Pathogenic	0.994
USH2A	O75445-1.3	C304L	Pathogenic	0.961
USH2A	O75445-1.3	C304M	Pathogenic	0.952
USH2A	O75445-1.3	C304N	Pathogenic	0.998
USH2A	O75445-1.3	C304P	Pathogenic	0.997
USH2A	O75445-1.3	C304Q	Pathogenic	0.996
USH2A	O75445-1.3	C304R	Pathogenic	0.991
USH2A	O75445-1.3	C304S	Pathogenic	0.985
USH2A	O75445-1.3	C304T	Pathogenic	0.985
USH2A	O75445-1.3	C304V	Pathogenic	0.973
USH2A	O75445-1.3	C304W	Pathogenic	0.955
USH2A	O75445-1.3	C304Y	Pathogenic	0.959
USH2A	O75445-1.3	P305A	Pathogenic	0.942
USH2A	O75445-1.3	P305C	Pathogenic	0.993
USH2A	O75445-1.3	P305D	Pathogenic	0.983
USH2A	O75445-1.3	P305E	Pathogenic	0.967
USH2A	O75445-1.3	P305F	Pathogenic	0.993
USH2A	O75445-1.3	P305G	Pathogenic	0.959
USH2A	O75445-1.3	P305H	Pathogenic	0.972
USH2A	O75445-1.3	P305I	Pathogenic	0.988
USH2A	O75445-1.3	P305K	Pathogenic	0.939
USH2A	O75445-1.3	P305L	Pathogenic	0.988
USH2A	O75445-1.3	P305M	Pathogenic	0.965
USH2A	O75445-1.3	P305N	Pathogenic	0.99
USH2A	O75445-1.3	P305Q	Pathogenic	0.953
USH2A	O75445-1.3	P305R	Pathogenic	0.959
USH2A	O75445-1.3	P305S	Pathogenic	0.959
USH2A	O75445-1.3	P305T	Pathogenic	0.969
USH2A	O75445-1.3	P305V	Pathogenic	0.98
USH2A	O75445-1.3	P305W	Pathogenic	0.985
USH2A	O75445-1.3	P305Y	Pathogenic	0.969
USH2A	O75445-1.3	G306A	Neutral	0.088
USH2A	O75445-1.3	G306C	Neutral	0.466
USH2A	O75445-1.3	G306D	Neutral	0.114
USH2A	O75445-1.3	G306E	Neutral	0.133
USH2A	O75445-1.3	G306F	Neutral	0.213
USH2A	O75445-1.3	G306H	Neutral	0.082
USH2A	O75445-1.3	G306I	Neutral	0.469
USH2A	O75445-1.3	G306K	Neutral	0.074
USH2A	O75445-1.3	G306L	Neutral	0.457
USH2A	O75445-1.3	G306M	Neutral	0.226
USH2A	O75445-1.3	G306N	Neutral	0.042
USH2A	O75445-1.3	G306P	Neutral	0.228
USH2A	O75445-1.3	G306Q	Neutral	0.096
USH2A	O75445-1.3	G306R	Neutral	0.05
USH2A	O75445-1.3	G306S	Neutral	0.065
USH2A	O75445-1.3	G306T	Neutral	0.176
USH2A	O75445-1.3	G306V	Neutral	0.348
USH2A	O75445-1.3	G306W	Neutral	0.057
USH2A	O75445-1.3	G306Y	Neutral	0.129
USH2A	O75445-1.3	S307A	Pathogenic	0.548
USH2A	O75445-1.3	S307C	Pathogenic	0.876
USH2A	O75445-1.3	S307D	Pathogenic	0.696
USH2A	O75445-1.3	S307E	Pathogenic	0.546
USH2A	O75445-1.3	S307F	Pathogenic	0.833
USH2A	O75445-1.3	S307G	Pathogenic	0.564
USH2A	O75445-1.3	S307H	Pathogenic	0.624
USH2A	O75445-1.3	S307I	Pathogenic	0.877
USH2A	O75445-1.3	S307K	Neutral	0.383
USH2A	O75445-1.3	S307L	Pathogenic	0.872
USH2A	O75445-1.3	S307M	Pathogenic	0.702
USH2A	O75445-1.3	S307N	Neutral	0.44
USH2A	O75445-1.3	S307P	Pathogenic	0.845
USH2A	O75445-1.3	S307Q	Neutral	0.454
USH2A	O75445-1.3	S307R	Neutral	0.485
USH2A	O75445-1.3	S307T	Neutral	0.43
USH2A	O75445-1.3	S307V	Pathogenic	0.908
USH2A	O75445-1.3	S307W	Pathogenic	0.854
USH2A	O75445-1.3	S307Y	Pathogenic	0.732
USH2A	O75445-1.3	H308A	Pathogenic	0.966
USH2A	O75445-1.3	H308C	Pathogenic	0.994
USH2A	O75445-1.3	H308D	Pathogenic	0.975
USH2A	O75445-1.3	H308E	Pathogenic	0.966
USH2A	O75445-1.3	H308F	Pathogenic	0.987
USH2A	O75445-1.3	H308G	Pathogenic	0.939
USH2A	O75445-1.3	H308I	Pathogenic	0.998
USH2A	O75445-1.3	H308K	Pathogenic	0.984
USH2A	O75445-1.3	H308L	Pathogenic	0.998
USH2A	O75445-1.3	H308M	Pathogenic	0.995
USH2A	O75445-1.3	H308N	Pathogenic	0.89
USH2A	O75445-1.3	H308P	Pathogenic	0.987
USH2A	O75445-1.3	H308Q	Pathogenic	0.965
USH2A	O75445-1.3	H308R	Pathogenic	0.946
USH2A	O75445-1.3	H308S	Pathogenic	0.938
USH2A	O75445-1.3	H308T	Pathogenic	0.985
USH2A	O75445-1.3	H308V	Pathogenic	0.997
USH2A	O75445-1.3	H308W	Pathogenic	0.989
USH2A	O75445-1.3	H308Y	Pathogenic	0.782
USH2A	O75445-1.3	P309A	Pathogenic	0.861
USH2A	O75445-1.3	P309C	Pathogenic	0.982
USH2A	O75445-1.3	P309D	Pathogenic	0.955
USH2A	O75445-1.3	P309E	Pathogenic	0.918
USH2A	O75445-1.3	P309F	Pathogenic	0.981
USH2A	O75445-1.3	P309G	Pathogenic	0.899
USH2A	O75445-1.3	P309H	Pathogenic	0.929
USH2A	O75445-1.3	P309I	Pathogenic	0.969
USH2A	O75445-1.3	P309K	Pathogenic	0.853
USH2A	O75445-1.3	P309L	Pathogenic	0.968
USH2A	O75445-1.3	P309M	Pathogenic	0.912
USH2A	O75445-1.3	P309N	Pathogenic	0.975
USH2A	O75445-1.3	P309Q	Pathogenic	0.886
USH2A	O75445-1.3	P309R	Pathogenic	0.898
USH2A	O75445-1.3	P309S	Pathogenic	0.899
USH2A	O75445-1.3	P309T	Pathogenic	0.923
USH2A	O75445-1.3	P309V	Pathogenic	0.95
USH2A	O75445-1.3	P309W	Pathogenic	0.963
USH2A	O75445-1.3	P309Y	Pathogenic	0.923
USH2A	O75445-1.3	R310A	Pathogenic	0.78
USH2A	O75445-1.3	R310C	Pathogenic	0.979
USH2A	O75445-1.3	R310D	Pathogenic	0.911
USH2A	O75445-1.3	R310E	Pathogenic	0.789
USH2A	O75445-1.3	R310F	Pathogenic	0.997
USH2A	O75445-1.3	R310G	Pathogenic	0.791
USH2A	O75445-1.3	R310H	Pathogenic	0.88
USH2A	O75445-1.3	R310I	Pathogenic	0.996
USH2A	O75445-1.3	R310K	Pathogenic	0.582
USH2A	O75445-1.3	R310L	Pathogenic	0.99
USH2A	O75445-1.3	R310M	Pathogenic	0.972
USH2A	O75445-1.3	R310N	Pathogenic	0.715
USH2A	O75445-1.3	R310P	Pathogenic	0.954
USH2A	O75445-1.3	R310Q	Pathogenic	0.703
USH2A	O75445-1.3	R310S	Pathogenic	0.784
USH2A	O75445-1.3	R310T	Pathogenic	0.889
USH2A	O75445-1.3	R310V	Pathogenic	0.99
USH2A	O75445-1.3	R310W	Pathogenic	0.998
USH2A	O75445-1.3	R310Y	Pathogenic	0.992
USH2A	O75445-1.3	V311A	Pathogenic	0.665
USH2A	O75445-1.3	V311C	Pathogenic	0.856
USH2A	O75445-1.3	V311D	Pathogenic	0.989
USH2A	O75445-1.3	V311E	Pathogenic	0.98
USH2A	O75445-1.3	V311F	Pathogenic	0.832
USH2A	O75445-1.3	V311G	Pathogenic	0.937
USH2A	O75445-1.3	V311H	Pathogenic	0.983
USH2A	O75445-1.3	V311I	Neutral	0.207
USH2A	O75445-1.3	V311K	Pathogenic	0.962
USH2A	O75445-1.3	V311L	Pathogenic	0.564
USH2A	O75445-1.3	V311M	Pathogenic	0.506
USH2A	O75445-1.3	V311N	Pathogenic	0.989
USH2A	O75445-1.3	V311P	Pathogenic	0.946
USH2A	O75445-1.3	V311Q	Pathogenic	0.971
USH2A	O75445-1.3	V311R	Pathogenic	0.975
USH2A	O75445-1.3	V311S	Pathogenic	0.937
USH2A	O75445-1.3	V311T	Pathogenic	0.824
USH2A	O75445-1.3	V311W	Pathogenic	0.93
USH2A	O75445-1.3	V311Y	Pathogenic	0.777
USH2A	O75445-1.3	H312A	Pathogenic	0.882
USH2A	O75445-1.3	H312C	Pathogenic	0.978
USH2A	O75445-1.3	H312D	Pathogenic	0.91
USH2A	O75445-1.3	H312E	Pathogenic	0.881
USH2A	O75445-1.3	H312F	Pathogenic	0.953
USH2A	O75445-1.3	H312G	Pathogenic	0.799
USH2A	O75445-1.3	H312I	Pathogenic	0.993
USH2A	O75445-1.3	H312K	Pathogenic	0.94
USH2A	O75445-1.3	H312L	Pathogenic	0.993
USH2A	O75445-1.3	H312M	Pathogenic	0.98
USH2A	O75445-1.3	H312N	Pathogenic	0.677
USH2A	O75445-1.3	H312P	Pathogenic	0.95
USH2A	O75445-1.3	H312Q	Pathogenic	0.876
USH2A	O75445-1.3	H312R	Pathogenic	0.819
USH2A	O75445-1.3	H312S	Pathogenic	0.798
USH2A	O75445-1.3	H312T	Pathogenic	0.944
USH2A	O75445-1.3	H312V	Pathogenic	0.989
USH2A	O75445-1.3	H312W	Pathogenic	0.96
USH2A	O75445-1.3	H312Y	Neutral	0.483
USH2A	O75445-1.3	P313A	Pathogenic	0.884
USH2A	O75445-1.3	P313C	Pathogenic	0.985
USH2A	O75445-1.3	P313D	Pathogenic	0.963
USH2A	O75445-1.3	P313E	Pathogenic	0.932
USH2A	O75445-1.3	P313F	Pathogenic	0.984
USH2A	O75445-1.3	P313G	Pathogenic	0.916
USH2A	O75445-1.3	P313H	Pathogenic	0.942
USH2A	O75445-1.3	P313I	Pathogenic	0.975
USH2A	O75445-1.3	P313K	Pathogenic	0.877
USH2A	O75445-1.3	P313L	Pathogenic	0.974
USH2A	O75445-1.3	P313M	Pathogenic	0.928
USH2A	O75445-1.3	P313N	Pathogenic	0.979
USH2A	O75445-1.3	P313Q	Pathogenic	0.905
USH2A	O75445-1.3	P313R	Pathogenic	0.915
USH2A	O75445-1.3	P313S	Pathogenic	0.916
USH2A	O75445-1.3	P313T	Pathogenic	0.937
USH2A	O75445-1.3	P313V	Pathogenic	0.959
USH2A	O75445-1.3	P313W	Pathogenic	0.969
USH2A	O75445-1.3	P313Y	Pathogenic	0.937
USH2A	O75445-1.3	L314A	Pathogenic	0.553
USH2A	O75445-1.3	L314C	Pathogenic	0.619
USH2A	O75445-1.3	L314D	Pathogenic	0.982
USH2A	O75445-1.3	L314E	Pathogenic	0.975
USH2A	O75445-1.3	L314F	Pathogenic	0.553
USH2A	O75445-1.3	L314G	Pathogenic	0.903
USH2A	O75445-1.3	L314H	Pathogenic	0.973
USH2A	O75445-1.3	L314I	Neutral	0.254
USH2A	O75445-1.3	L314K	Pathogenic	0.959
USH2A	O75445-1.3	L314M	Neutral	0.29
USH2A	O75445-1.3	L314N	Pathogenic	0.963
USH2A	O75445-1.3	L314P	Pathogenic	0.917
USH2A	O75445-1.3	L314Q	Pathogenic	0.943
USH2A	O75445-1.3	L314R	Pathogenic	0.94
USH2A	O75445-1.3	L314S	Pathogenic	0.802
USH2A	O75445-1.3	L314T	Pathogenic	0.745
USH2A	O75445-1.3	L314V	Neutral	0.338
USH2A	O75445-1.3	L314W	Pathogenic	0.768
USH2A	O75445-1.3	L314Y	Pathogenic	0.763
USH2A	O75445-1.3	A315C	Neutral	0.003
USH2A	O75445-1.3	A315D	Neutral	0.018
USH2A	O75445-1.3	A315E	Neutral	0.004
USH2A	O75445-1.3	A315F	Neutral	0.005
USH2A	O75445-1.3	A315G	Neutral	0.003
USH2A	O75445-1.3	A315H	Neutral	0.005
USH2A	O75445-1.3	A315I	Neutral	0.003
USH2A	O75445-1.3	A315K	Neutral	0.002
USH2A	O75445-1.3	A315L	Neutral	0.003
USH2A	O75445-1.3	A315M	Neutral	0.003
USH2A	O75445-1.3	A315N	Neutral	0.014
USH2A	O75445-1.3	A315P	Neutral	0.006
USH2A	O75445-1.3	A315Q	Neutral	0.003
USH2A	O75445-1.3	A315R	Neutral	0.001
USH2A	O75445-1.3	A315S	Neutral	0.002
USH2A	O75445-1.3	A315T	Neutral	0.002
USH2A	O75445-1.3	A315V	Neutral	0.002
USH2A	O75445-1.3	A315W	Neutral	0.006
USH2A	O75445-1.3	A315Y	Neutral	0.003
USH2A	O75445-1.3	Q316A	Neutral	0.455
USH2A	O75445-1.3	Q316C	Pathogenic	0.918
USH2A	O75445-1.3	Q316D	Neutral	0.444
USH2A	O75445-1.3	Q316E	Neutral	0.203
USH2A	O75445-1.3	Q316F	Pathogenic	0.954
USH2A	O75445-1.3	Q316G	Neutral	0.47
USH2A	O75445-1.3	Q316H	Pathogenic	0.571
USH2A	O75445-1.3	Q316I	Pathogenic	0.968
USH2A	O75445-1.3	Q316K	Neutral	0.294
USH2A	O75445-1.3	Q316L	Pathogenic	0.926
USH2A	O75445-1.3	Q316M	Pathogenic	0.655
USH2A	O75445-1.3	Q316N	Neutral	0.463
USH2A	O75445-1.3	Q316P	Pathogenic	0.681
USH2A	O75445-1.3	Q316R	Neutral	0.216
USH2A	O75445-1.3	Q316S	Neutral	0.272
USH2A	O75445-1.3	Q316T	Pathogenic	0.652
USH2A	O75445-1.3	Q316V	Pathogenic	0.91
USH2A	O75445-1.3	Q316W	Pathogenic	0.824
USH2A	O75445-1.3	Q316Y	Pathogenic	0.687
USH2A	O75445-1.3	R317A	Pathogenic	0.599
USH2A	O75445-1.3	R317C	Pathogenic	0.952
USH2A	O75445-1.3	R317D	Pathogenic	0.812
USH2A	O75445-1.3	R317E	Pathogenic	0.612
USH2A	O75445-1.3	R317F	Pathogenic	0.993
USH2A	O75445-1.3	R317G	Pathogenic	0.614
USH2A	O75445-1.3	R317H	Pathogenic	0.755
USH2A	O75445-1.3	R317I	Pathogenic	0.99
USH2A	O75445-1.3	R317K	Neutral	0.369
USH2A	O75445-1.3	R317L	Pathogenic	0.977
USH2A	O75445-1.3	R317M	Pathogenic	0.936
USH2A	O75445-1.3	R317N	Pathogenic	0.514
USH2A	O75445-1.3	R317P	Pathogenic	0.897
USH2A	O75445-1.3	R317Q	Neutral	0.499
USH2A	O75445-1.3	R317S	Pathogenic	0.604
USH2A	O75445-1.3	R317T	Pathogenic	0.77
USH2A	O75445-1.3	R317V	Pathogenic	0.976
USH2A	O75445-1.3	R317W	Pathogenic	0.994
USH2A	O75445-1.3	R317Y	Pathogenic	0.981
USH2A	O75445-1.3	Y318A	Pathogenic	0.776
USH2A	O75445-1.3	Y318C	Pathogenic	0.824
USH2A	O75445-1.3	Y318D	Pathogenic	0.967
USH2A	O75445-1.3	Y318E	Pathogenic	0.955
USH2A	O75445-1.3	Y318F	Neutral	0.351
USH2A	O75445-1.3	Y318G	Pathogenic	0.834
USH2A	O75445-1.3	Y318H	Neutral	0.417
USH2A	O75445-1.3	Y318I	Pathogenic	0.912
USH2A	O75445-1.3	Y318K	Pathogenic	0.983
USH2A	O75445-1.3	Y318L	Pathogenic	0.908
USH2A	O75445-1.3	Y318M	Pathogenic	0.887
USH2A	O75445-1.3	Y318N	Pathogenic	0.933
USH2A	O75445-1.3	Y318P	Pathogenic	0.931
USH2A	O75445-1.3	Y318Q	Pathogenic	0.899
USH2A	O75445-1.3	Y318R	Pathogenic	0.983
USH2A	O75445-1.3	Y318S	Pathogenic	0.833
USH2A	O75445-1.3	Y318T	Pathogenic	0.891
USH2A	O75445-1.3	Y318V	Pathogenic	0.809
USH2A	O75445-1.3	Y318W	Neutral	0.482
USH2A	O75445-1.3	C319A	Pathogenic	0.962
USH2A	O75445-1.3	C319D	Pathogenic	0.999
USH2A	O75445-1.3	C319E	Pathogenic	0.999
USH2A	O75445-1.3	C319F	Pathogenic	0.982
USH2A	O75445-1.3	C319G	Pathogenic	0.995
USH2A	O75445-1.3	C319H	Pathogenic	0.995
USH2A	O75445-1.3	C319I	Pathogenic	0.971
USH2A	O75445-1.3	C319K	Pathogenic	0.995
USH2A	O75445-1.3	C319L	Pathogenic	0.97
USH2A	O75445-1.3	C319M	Pathogenic	0.962
USH2A	O75445-1.3	C319N	Pathogenic	0.998
USH2A	O75445-1.3	C319P	Pathogenic	0.998
USH2A	O75445-1.3	C319Q	Pathogenic	0.997
USH2A	O75445-1.3	C319R	Pathogenic	0.993
USH2A	O75445-1.3	C319S	Pathogenic	0.988
USH2A	O75445-1.3	C319T	Pathogenic	0.989
USH2A	O75445-1.3	C319V	Pathogenic	0.979
USH2A	O75445-1.3	C319W	Pathogenic	0.965
USH2A	O75445-1.3	C319Y	Pathogenic	0.968
USH2A	O75445-1.3	I320A	Pathogenic	0.731
USH2A	O75445-1.3	I320C	Pathogenic	0.782
USH2A	O75445-1.3	I320D	Pathogenic	0.981
USH2A	O75445-1.3	I320E	Pathogenic	0.989
USH2A	O75445-1.3	I320F	Pathogenic	0.714
USH2A	O75445-1.3	I320G	Pathogenic	0.953
USH2A	O75445-1.3	I320H	Pathogenic	0.988
USH2A	O75445-1.3	I320K	Pathogenic	0.992
USH2A	O75445-1.3	I320L	Neutral	0.416
USH2A	O75445-1.3	I320M	Pathogenic	0.673
USH2A	O75445-1.3	I320N	Pathogenic	0.983
USH2A	O75445-1.3	I320P	Pathogenic	0.96
USH2A	O75445-1.3	I320Q	Pathogenic	0.988
USH2A	O75445-1.3	I320R	Pathogenic	0.987
USH2A	O75445-1.3	I320S	Pathogenic	0.899
USH2A	O75445-1.3	I320T	Pathogenic	0.865
USH2A	O75445-1.3	I320V	Neutral	0.177
USH2A	O75445-1.3	I320W	Pathogenic	0.938
USH2A	O75445-1.3	I320Y	Pathogenic	0.877
USH2A	O75445-1.3	P321A	Pathogenic	0.818
USH2A	O75445-1.3	P321C	Pathogenic	0.976
USH2A	O75445-1.3	P321D	Pathogenic	0.94
USH2A	O75445-1.3	P321E	Pathogenic	0.891
USH2A	O75445-1.3	P321F	Pathogenic	0.973
USH2A	O75445-1.3	P321G	Pathogenic	0.866
USH2A	O75445-1.3	P321H	Pathogenic	0.905
USH2A	O75445-1.3	P321I	Pathogenic	0.958
USH2A	O75445-1.3	P321K	Pathogenic	0.808
USH2A	O75445-1.3	P321L	Pathogenic	0.956
USH2A	O75445-1.3	P321M	Pathogenic	0.883
USH2A	O75445-1.3	P321N	Pathogenic	0.965
USH2A	O75445-1.3	P321Q	Pathogenic	0.85
USH2A	O75445-1.3	P321R	Pathogenic	0.865
USH2A	O75445-1.3	P321S	Pathogenic	0.866
USH2A	O75445-1.3	P321T	Pathogenic	0.897
USH2A	O75445-1.3	P321V	Pathogenic	0.933
USH2A	O75445-1.3	P321W	Pathogenic	0.949
USH2A	O75445-1.3	P321Y	Pathogenic	0.897
USH2A	O75445-1.3	N322A	Pathogenic	0.962
USH2A	O75445-1.3	N322C	Pathogenic	0.993
USH2A	O75445-1.3	N322D	Pathogenic	0.761
USH2A	O75445-1.3	N322E	Pathogenic	0.841
USH2A	O75445-1.3	N322F	Pathogenic	0.989
USH2A	O75445-1.3	N322G	Pathogenic	0.694
USH2A	O75445-1.3	N322H	Pathogenic	0.71
USH2A	O75445-1.3	N322I	Pathogenic	0.992
USH2A	O75445-1.3	N322K	Pathogenic	0.732
USH2A	O75445-1.3	N322L	Pathogenic	0.992
USH2A	O75445-1.3	N322M	Pathogenic	0.976
USH2A	O75445-1.3	N322P	Pathogenic	0.985
USH2A	O75445-1.3	N322Q	Pathogenic	0.842
USH2A	O75445-1.3	N322R	Pathogenic	0.644
USH2A	O75445-1.3	N322S	Pathogenic	0.685
USH2A	O75445-1.3	N322T	Pathogenic	0.916
USH2A	O75445-1.3	N322V	Pathogenic	0.994
USH2A	O75445-1.3	N322W	Pathogenic	0.99
USH2A	O75445-1.3	N322Y	Pathogenic	0.955
USH2A	O75445-1.3	D323A	Neutral	0.493
USH2A	O75445-1.3	D323C	Pathogenic	0.851
USH2A	O75445-1.3	D323E	Neutral	0.026
USH2A	O75445-1.3	D323F	Pathogenic	0.709
USH2A	O75445-1.3	D323G	Neutral	0.166
USH2A	O75445-1.3	D323H	Neutral	0.262
USH2A	O75445-1.3	D323I	Pathogenic	0.777
USH2A	O75445-1.3	D323K	Neutral	0.128
USH2A	O75445-1.3	D323L	Pathogenic	0.883
USH2A	O75445-1.3	D323M	Pathogenic	0.725
USH2A	O75445-1.3	D323N	Neutral	0.087
USH2A	O75445-1.3	D323P	Pathogenic	0.522
USH2A	O75445-1.3	D323Q	Neutral	0.129
USH2A	O75445-1.3	D323R	Neutral	0.181
USH2A	O75445-1.3	D323S	Neutral	0.16
USH2A	O75445-1.3	D323T	Neutral	0.457
USH2A	O75445-1.3	D323V	Pathogenic	0.828
USH2A	O75445-1.3	D323W	Pathogenic	0.74
USH2A	O75445-1.3	D323Y	Pathogenic	0.571
USH2A	O75445-1.3	A324C	Neutral	0.397
USH2A	O75445-1.3	A324D	Pathogenic	0.781
USH2A	O75445-1.3	A324E	Neutral	0.451
USH2A	O75445-1.3	A324F	Pathogenic	0.515
USH2A	O75445-1.3	A324G	Neutral	0.354
USH2A	O75445-1.3	A324H	Neutral	0.489
USH2A	O75445-1.3	A324I	Neutral	0.4
USH2A	O75445-1.3	A324K	Neutral	0.298
USH2A	O75445-1.3	A324L	Neutral	0.388
USH2A	O75445-1.3	A324M	Neutral	0.334
USH2A	O75445-1.3	A324N	Pathogenic	0.736
USH2A	O75445-1.3	A324P	Pathogenic	0.537
USH2A	O75445-1.3	A324Q	Neutral	0.362
USH2A	O75445-1.3	A324R	Neutral	0.22
USH2A	O75445-1.3	A324S	Neutral	0.271
USH2A	O75445-1.3	A324T	Neutral	0.278
USH2A	O75445-1.3	A324V	Neutral	0.286
USH2A	O75445-1.3	A324W	Pathogenic	0.553
USH2A	O75445-1.3	A324Y	Neutral	0.367
USH2A	O75445-1.3	G325A	Neutral	0.012
USH2A	O75445-1.3	G325C	Neutral	0.099
USH2A	O75445-1.3	G325D	Neutral	0.016
USH2A	O75445-1.3	G325E	Neutral	0.019
USH2A	O75445-1.3	G325F	Neutral	0.033
USH2A	O75445-1.3	G325H	Neutral	0.011
USH2A	O75445-1.3	G325I	Neutral	0.1
USH2A	O75445-1.3	G325K	Neutral	0.01
USH2A	O75445-1.3	G325L	Neutral	0.096
USH2A	O75445-1.3	G325M	Neutral	0.035
USH2A	O75445-1.3	G325N	Neutral	0.006
USH2A	O75445-1.3	G325P	Neutral	0.036
USH2A	O75445-1.3	G325Q	Neutral	0.013
USH2A	O75445-1.3	G325R	Neutral	0.007
USH2A	O75445-1.3	G325S	Neutral	0.009
USH2A	O75445-1.3	G325T	Neutral	0.026
USH2A	O75445-1.3	G325V	Neutral	0.063
USH2A	O75445-1.3	G325W	Neutral	0.008
USH2A	O75445-1.3	G325Y	Neutral	0.018
USH2A	O75445-1.3	D326A	Pathogenic	0.978
USH2A	O75445-1.3	D326C	Pathogenic	0.996
USH2A	O75445-1.3	D326E	Pathogenic	0.55
USH2A	O75445-1.3	D326F	Pathogenic	0.991
USH2A	O75445-1.3	D326G	Pathogenic	0.9
USH2A	O75445-1.3	D326H	Pathogenic	0.941
USH2A	O75445-1.3	D326I	Pathogenic	0.994
USH2A	O75445-1.3	D326K	Pathogenic	0.868
USH2A	O75445-1.3	D326L	Pathogenic	0.997
USH2A	O75445-1.3	D326M	Pathogenic	0.992
USH2A	O75445-1.3	D326N	Pathogenic	0.812
USH2A	O75445-1.3	D326P	Pathogenic	0.98
USH2A	O75445-1.3	D326Q	Pathogenic	0.87
USH2A	O75445-1.3	D326R	Pathogenic	0.909
USH2A	O75445-1.3	D326S	Pathogenic	0.896
USH2A	O75445-1.3	D326T	Pathogenic	0.974
USH2A	O75445-1.3	D326V	Pathogenic	0.995
USH2A	O75445-1.3	D326W	Pathogenic	0.992
USH2A	O75445-1.3	D326Y	Pathogenic	0.984
USH2A	O75445-1.3	T327A	Pathogenic	0.68
USH2A	O75445-1.3	T327C	Pathogenic	0.926
USH2A	O75445-1.3	T327D	Pathogenic	0.945
USH2A	O75445-1.3	T327E	Pathogenic	0.91
USH2A	O75445-1.3	T327F	Pathogenic	0.933
USH2A	O75445-1.3	T327G	Pathogenic	0.87
USH2A	O75445-1.3	T327H	Pathogenic	0.922
USH2A	O75445-1.3	T327I	Pathogenic	0.897
USH2A	O75445-1.3	T327K	Pathogenic	0.84
USH2A	O75445-1.3	T327L	Pathogenic	0.892
USH2A	O75445-1.3	T327M	Pathogenic	0.867
USH2A	O75445-1.3	T327N	Pathogenic	0.869
USH2A	O75445-1.3	T327P	Pathogenic	0.926
USH2A	O75445-1.3	T327Q	Pathogenic	0.876
USH2A	O75445-1.3	T327R	Pathogenic	0.777
USH2A	O75445-1.3	T327S	Pathogenic	0.56
USH2A	O75445-1.3	T327V	Pathogenic	0.84
USH2A	O75445-1.3	T327W	Pathogenic	0.876
USH2A	O75445-1.3	T327Y	Pathogenic	0.883
USH2A	O75445-1.3	A328C	Neutral	0.128
USH2A	O75445-1.3	A328D	Neutral	0.443
USH2A	O75445-1.3	A328E	Neutral	0.155
USH2A	O75445-1.3	A328F	Neutral	0.191
USH2A	O75445-1.3	A328G	Neutral	0.109
USH2A	O75445-1.3	A328H	Neutral	0.176
USH2A	O75445-1.3	A328I	Neutral	0.129
USH2A	O75445-1.3	A328K	Neutral	0.086
USH2A	O75445-1.3	A328L	Neutral	0.124
USH2A	O75445-1.3	A328M	Neutral	0.1
USH2A	O75445-1.3	A328N	Neutral	0.384
USH2A	O75445-1.3	A328P	Neutral	0.205
USH2A	O75445-1.3	A328Q	Neutral	0.112
USH2A	O75445-1.3	A328R	Neutral	0.059
USH2A	O75445-1.3	A328S	Neutral	0.076
USH2A	O75445-1.3	A328T	Neutral	0.079
USH2A	O75445-1.3	A328V	Neutral	0.082
USH2A	O75445-1.3	A328W	Neutral	0.216
USH2A	O75445-1.3	A328Y	Neutral	0.114
USH2A	O75445-1.3	D329A	Neutral	0.027
USH2A	O75445-1.3	D329C	Neutral	0.141
USH2A	O75445-1.3	D329E	Neutral	0.001
USH2A	O75445-1.3	D329F	Neutral	0.065
USH2A	O75445-1.3	D329G	Neutral	0.006
USH2A	O75445-1.3	D329H	Neutral	0.01
USH2A	O75445-1.3	D329I	Neutral	0.091
USH2A	O75445-1.3	D329K	Neutral	0.004
USH2A	O75445-1.3	D329L	Neutral	0.178
USH2A	O75445-1.3	D329M	Neutral	0.07
USH2A	O75445-1.3	D329N	Neutral	0.003
USH2A	O75445-1.3	D329P	Neutral	0.03
USH2A	O75445-1.3	D329Q	Neutral	0.004
USH2A	O75445-1.3	D329R	Neutral	0.006
USH2A	O75445-1.3	D329S	Neutral	0.005
USH2A	O75445-1.3	D329T	Neutral	0.024
USH2A	O75445-1.3	D329V	Neutral	0.121
USH2A	O75445-1.3	D329W	Neutral	0.075
USH2A	O75445-1.3	D329Y	Neutral	0.037
USH2A	O75445-1.3	N330A	Neutral	0.326
USH2A	O75445-1.3	N330C	Pathogenic	0.74
USH2A	O75445-1.3	N330D	Neutral	0.057
USH2A	O75445-1.3	N330E	Neutral	0.091
USH2A	O75445-1.3	N330F	Pathogenic	0.626
USH2A	O75445-1.3	N330G	Neutral	0.041
USH2A	O75445-1.3	N330H	Neutral	0.045
USH2A	O75445-1.3	N330I	Pathogenic	0.706
USH2A	O75445-1.3	N330K	Neutral	0.049
USH2A	O75445-1.3	N330L	Pathogenic	0.695
USH2A	O75445-1.3	N330M	Neutral	0.441
USH2A	O75445-1.3	N330P	Pathogenic	0.554
USH2A	O75445-1.3	N330Q	Neutral	0.092
USH2A	O75445-1.3	N330R	Neutral	0.033
USH2A	O75445-1.3	N330S	Neutral	0.04
USH2A	O75445-1.3	N330T	Neutral	0.172
USH2A	O75445-1.3	N330V	Pathogenic	0.767
USH2A	O75445-1.3	N330W	Pathogenic	0.661
USH2A	O75445-1.3	N330Y	Neutral	0.286
USH2A	O75445-1.3	R331A	Pathogenic	0.652
USH2A	O75445-1.3	R331C	Pathogenic	0.962
USH2A	O75445-1.3	R331D	Pathogenic	0.844
USH2A	O75445-1.3	R331E	Pathogenic	0.664
USH2A	O75445-1.3	R331F	Pathogenic	0.995
USH2A	O75445-1.3	R331G	Pathogenic	0.666
USH2A	O75445-1.3	R331H	Pathogenic	0.794
USH2A	O75445-1.3	R331I	Pathogenic	0.992
USH2A	O75445-1.3	R331K	Neutral	0.423
USH2A	O75445-1.3	R331L	Pathogenic	0.982
USH2A	O75445-1.3	R331M	Pathogenic	0.949
USH2A	O75445-1.3	R331N	Pathogenic	0.57
USH2A	O75445-1.3	R331P	Pathogenic	0.916
USH2A	O75445-1.3	R331Q	Pathogenic	0.555
USH2A	O75445-1.3	R331S	Pathogenic	0.657
USH2A	O75445-1.3	R331T	Pathogenic	0.808
USH2A	O75445-1.3	R331V	Pathogenic	0.981
USH2A	O75445-1.3	R331W	Pathogenic	0.995
USH2A	O75445-1.3	R331Y	Pathogenic	0.985
USH2A	O75445-1.3	V332A	Neutral	0.391
USH2A	O75445-1.3	V332C	Pathogenic	0.658
USH2A	O75445-1.3	V332D	Pathogenic	0.966
USH2A	O75445-1.3	V332E	Pathogenic	0.941
USH2A	O75445-1.3	V332F	Pathogenic	0.615
USH2A	O75445-1.3	V332G	Pathogenic	0.829
USH2A	O75445-1.3	V332H	Pathogenic	0.949
USH2A	O75445-1.3	V332I	Neutral	0.078
USH2A	O75445-1.3	V332K	Pathogenic	0.892
USH2A	O75445-1.3	V332L	Neutral	0.295
USH2A	O75445-1.3	V332M	Neutral	0.249
USH2A	O75445-1.3	V332N	Pathogenic	0.968
USH2A	O75445-1.3	V332P	Pathogenic	0.851
USH2A	O75445-1.3	V332Q	Pathogenic	0.917
USH2A	O75445-1.3	V332R	Pathogenic	0.926
USH2A	O75445-1.3	V332S	Pathogenic	0.828
USH2A	O75445-1.3	V332T	Pathogenic	0.602
USH2A	O75445-1.3	V332W	Pathogenic	0.81
USH2A	O75445-1.3	V332Y	Pathogenic	0.53
USH2A	O75445-1.3	S333A	Neutral	0.126
USH2A	O75445-1.3	S333C	Neutral	0.455
USH2A	O75445-1.3	S333D	Neutral	0.213
USH2A	O75445-1.3	S333E	Neutral	0.124
USH2A	O75445-1.3	S333F	Neutral	0.371
USH2A	O75445-1.3	S333G	Neutral	0.133
USH2A	O75445-1.3	S333H	Neutral	0.164
USH2A	O75445-1.3	S333I	Neutral	0.459
USH2A	O75445-1.3	S333K	Neutral	0.068
USH2A	O75445-1.3	S333L	Neutral	0.446
USH2A	O75445-1.3	S333M	Neutral	0.218
USH2A	O75445-1.3	S333N	Neutral	0.085
USH2A	O75445-1.3	S333P	Neutral	0.392
USH2A	O75445-1.3	S333Q	Neutral	0.09
USH2A	O75445-1.3	S333R	Neutral	0.1
USH2A	O75445-1.3	S333T	Neutral	0.082
USH2A	O75445-1.3	S333V	Pathogenic	0.538
USH2A	O75445-1.3	S333W	Neutral	0.408
USH2A	O75445-1.3	S333Y	Neutral	0.244
USH2A	O75445-1.3	R334A	Pathogenic	0.886
USH2A	O75445-1.3	R334C	Pathogenic	0.991
USH2A	O75445-1.3	R334D	Pathogenic	0.957
USH2A	O75445-1.3	R334E	Pathogenic	0.891
USH2A	O75445-1.3	R334F	Pathogenic	0.999
USH2A	O75445-1.3	R334G	Pathogenic	0.892
USH2A	O75445-1.3	R334H	Pathogenic	0.941
USH2A	O75445-1.3	R334I	Pathogenic	0.998
USH2A	O75445-1.3	R334K	Pathogenic	0.753
USH2A	O75445-1.3	R334L	Pathogenic	0.995
USH2A	O75445-1.3	R334M	Pathogenic	0.987
USH2A	O75445-1.3	R334N	Pathogenic	0.846
USH2A	O75445-1.3	R334P	Pathogenic	0.979
USH2A	O75445-1.3	R334Q	Pathogenic	0.838
USH2A	O75445-1.3	R334S	Pathogenic	0.888
USH2A	O75445-1.3	R334T	Pathogenic	0.946
USH2A	O75445-1.3	R334V	Pathogenic	0.995
USH2A	O75445-1.3	R334W	Pathogenic	0.999
USH2A	O75445-1.3	R334Y	Pathogenic	0.996
USH2A	O75445-1.3	L335A	Pathogenic	0.822
USH2A	O75445-1.3	L335C	Pathogenic	0.859
USH2A	O75445-1.3	L335D	Pathogenic	0.995
USH2A	O75445-1.3	L335E	Pathogenic	0.993
USH2A	O75445-1.3	L335F	Pathogenic	0.823
USH2A	O75445-1.3	L335G	Pathogenic	0.972
USH2A	O75445-1.3	L335H	Pathogenic	0.993
USH2A	O75445-1.3	L335I	Pathogenic	0.561
USH2A	O75445-1.3	L335K	Pathogenic	0.989
USH2A	O75445-1.3	L335M	Pathogenic	0.605
USH2A	O75445-1.3	L335N	Pathogenic	0.99
USH2A	O75445-1.3	L335P	Pathogenic	0.976
USH2A	O75445-1.3	L335Q	Pathogenic	0.984
USH2A	O75445-1.3	L335R	Pathogenic	0.983
USH2A	O75445-1.3	L335S	Pathogenic	0.938
USH2A	O75445-1.3	L335T	Pathogenic	0.916
USH2A	O75445-1.3	L335V	Pathogenic	0.657
USH2A	O75445-1.3	L335W	Pathogenic	0.925
USH2A	O75445-1.3	L335Y	Pathogenic	0.924
USH2A	O75445-1.3	N336A	Pathogenic	0.842
USH2A	O75445-1.3	N336C	Pathogenic	0.969
USH2A	O75445-1.3	N336D	Neutral	0.4
USH2A	O75445-1.3	N336E	Pathogenic	0.525
USH2A	O75445-1.3	N336F	Pathogenic	0.948
USH2A	O75445-1.3	N336G	Neutral	0.322
USH2A	O75445-1.3	N336H	Neutral	0.339
USH2A	O75445-1.3	N336I	Pathogenic	0.963
USH2A	O75445-1.3	N336K	Neutral	0.363
USH2A	O75445-1.3	N336L	Pathogenic	0.962
USH2A	O75445-1.3	N336M	Pathogenic	0.897
USH2A	O75445-1.3	N336P	Pathogenic	0.932
USH2A	O75445-1.3	N336Q	Pathogenic	0.528
USH2A	O75445-1.3	N336R	Neutral	0.275
USH2A	O75445-1.3	N336S	Neutral	0.313
USH2A	O75445-1.3	N336T	Pathogenic	0.696
USH2A	O75445-1.3	N336V	Pathogenic	0.973
USH2A	O75445-1.3	N336W	Pathogenic	0.955
USH2A	O75445-1.3	N336Y	Pathogenic	0.815
USH2A	O75445-1.3	P337A	Neutral	0.07
USH2A	O75445-1.3	P337C	Neutral	0.402
USH2A	O75445-1.3	P337D	Neutral	0.207
USH2A	O75445-1.3	P337E	Neutral	0.12
USH2A	O75445-1.3	P337F	Neutral	0.38
USH2A	O75445-1.3	P337G	Neutral	0.098
USH2A	O75445-1.3	P337H	Neutral	0.138
USH2A	O75445-1.3	P337I	Neutral	0.278
USH2A	O75445-1.3	P337K	Neutral	0.066
USH2A	O75445-1.3	P337L	Neutral	0.268
USH2A	O75445-1.3	P337M	Neutral	0.113
USH2A	O75445-1.3	P337N	Neutral	0.318
USH2A	O75445-1.3	P337Q	Neutral	0.087
USH2A	O75445-1.3	P337R	Neutral	0.097
USH2A	O75445-1.3	P337S	Neutral	0.098
USH2A	O75445-1.3	P337T	Neutral	0.128
USH2A	O75445-1.3	P337V	Neutral	0.188
USH2A	O75445-1.3	P337W	Neutral	0.239
USH2A	O75445-1.3	P337Y	Neutral	0.128
USH2A	O75445-1.3	E338A	Neutral	0.337
USH2A	O75445-1.3	E338C	Pathogenic	0.94
USH2A	O75445-1.3	E338D	Neutral	0.058
USH2A	O75445-1.3	E338F	Pathogenic	0.902
USH2A	O75445-1.3	E338G	Neutral	0.351
USH2A	O75445-1.3	E338H	Neutral	0.37
USH2A	O75445-1.3	E338I	Pathogenic	0.93
USH2A	O75445-1.3	E338K	Neutral	0.108
USH2A	O75445-1.3	E338L	Pathogenic	0.926
USH2A	O75445-1.3	E338M	Pathogenic	0.814
USH2A	O75445-1.3	E338N	Neutral	0.264
USH2A	O75445-1.3	E338P	Pathogenic	0.566
USH2A	O75445-1.3	E338Q	Neutral	0.097
USH2A	O75445-1.3	E338R	Neutral	0.155
USH2A	O75445-1.3	E338S	Neutral	0.185
USH2A	O75445-1.3	E338T	Pathogenic	0.533
USH2A	O75445-1.3	E338V	Pathogenic	0.861
USH2A	O75445-1.3	E338W	Pathogenic	0.825
USH2A	O75445-1.3	E338Y	Pathogenic	0.689
USH2A	O75445-1.3	A339C	Pathogenic	0.8
USH2A	O75445-1.3	A339D	Pathogenic	0.956
USH2A	O75445-1.3	A339E	Pathogenic	0.833
USH2A	O75445-1.3	A339F	Pathogenic	0.866
USH2A	O75445-1.3	A339G	Pathogenic	0.77
USH2A	O75445-1.3	A339H	Pathogenic	0.854
USH2A	O75445-1.3	A339I	Pathogenic	0.802
USH2A	O75445-1.3	A339K	Pathogenic	0.721
USH2A	O75445-1.3	A339L	Pathogenic	0.794
USH2A	O75445-1.3	A339M	Pathogenic	0.754
USH2A	O75445-1.3	A339N	Pathogenic	0.945
USH2A	O75445-1.3	A339P	Pathogenic	0.876
USH2A	O75445-1.3	A339Q	Pathogenic	0.776
USH2A	O75445-1.3	A339R	Pathogenic	0.632
USH2A	O75445-1.3	A339S	Pathogenic	0.694
USH2A	O75445-1.3	A339T	Pathogenic	0.701
USH2A	O75445-1.3	A339V	Pathogenic	0.71
USH2A	O75445-1.3	A339W	Pathogenic	0.883
USH2A	O75445-1.3	A339Y	Pathogenic	0.779
USH2A	O75445-1.3	H340A	Pathogenic	0.978
USH2A	O75445-1.3	H340C	Pathogenic	0.996
USH2A	O75445-1.3	H340D	Pathogenic	0.984
USH2A	O75445-1.3	H340E	Pathogenic	0.978
USH2A	O75445-1.3	H340F	Pathogenic	0.992
USH2A	O75445-1.3	H340G	Pathogenic	0.959
USH2A	O75445-1.3	H340I	Pathogenic	0.999
USH2A	O75445-1.3	H340K	Pathogenic	0.989
USH2A	O75445-1.3	H340L	Pathogenic	0.999
USH2A	O75445-1.3	H340M	Pathogenic	0.997
USH2A	O75445-1.3	H340N	Pathogenic	0.926
USH2A	O75445-1.3	H340P	Pathogenic	0.991
USH2A	O75445-1.3	H340Q	Pathogenic	0.977
USH2A	O75445-1.3	H340R	Pathogenic	0.964
USH2A	O75445-1.3	H340S	Pathogenic	0.959
USH2A	O75445-1.3	H340T	Pathogenic	0.99
USH2A	O75445-1.3	H340V	Pathogenic	0.998
USH2A	O75445-1.3	H340W	Pathogenic	0.993
USH2A	O75445-1.3	H340Y	Pathogenic	0.847
USH2A	O75445-1.3	P341A	Pathogenic	0.907
USH2A	O75445-1.3	P341C	Pathogenic	0.989
USH2A	O75445-1.3	P341D	Pathogenic	0.971
USH2A	O75445-1.3	P341E	Pathogenic	0.947
USH2A	O75445-1.3	P341F	Pathogenic	0.988
USH2A	O75445-1.3	P341G	Pathogenic	0.934
USH2A	O75445-1.3	P341H	Pathogenic	0.954
USH2A	O75445-1.3	P341I	Pathogenic	0.98
USH2A	O75445-1.3	P341K	Pathogenic	0.902
USH2A	O75445-1.3	P341L	Pathogenic	0.979
USH2A	O75445-1.3	P341M	Pathogenic	0.943
USH2A	O75445-1.3	P341N	Pathogenic	0.984
USH2A	O75445-1.3	P341Q	Pathogenic	0.925
USH2A	O75445-1.3	P341R	Pathogenic	0.933
USH2A	O75445-1.3	P341S	Pathogenic	0.934
USH2A	O75445-1.3	P341T	Pathogenic	0.95
USH2A	O75445-1.3	P341V	Pathogenic	0.968
USH2A	O75445-1.3	P341W	Pathogenic	0.976
USH2A	O75445-1.3	P341Y	Pathogenic	0.95
USH2A	O75445-1.3	L342A	Pathogenic	0.845
USH2A	O75445-1.3	L342C	Pathogenic	0.878
USH2A	O75445-1.3	L342D	Pathogenic	0.996
USH2A	O75445-1.3	L342E	Pathogenic	0.994
USH2A	O75445-1.3	L342F	Pathogenic	0.845
USH2A	O75445-1.3	L342G	Pathogenic	0.976
USH2A	O75445-1.3	L342H	Pathogenic	0.994
USH2A	O75445-1.3	L342I	Pathogenic	0.6
USH2A	O75445-1.3	L342K	Pathogenic	0.99
USH2A	O75445-1.3	L342M	Pathogenic	0.643
USH2A	O75445-1.3	L342N	Pathogenic	0.991
USH2A	O75445-1.3	L342P	Pathogenic	0.98
USH2A	O75445-1.3	L342Q	Pathogenic	0.987
USH2A	O75445-1.3	L342R	Pathogenic	0.986
USH2A	O75445-1.3	L342S	Pathogenic	0.947
USH2A	O75445-1.3	L342T	Pathogenic	0.928
USH2A	O75445-1.3	L342V	Pathogenic	0.692
USH2A	O75445-1.3	L342W	Pathogenic	0.936
USH2A	O75445-1.3	L342Y	Pathogenic	0.934
USH2A	O75445-1.3	S343A	Neutral	0.059
USH2A	O75445-1.3	S343C	Neutral	0.268
USH2A	O75445-1.3	S343D	Neutral	0.106
USH2A	O75445-1.3	S343E	Neutral	0.059
USH2A	O75445-1.3	S343F	Neutral	0.205
USH2A	O75445-1.3	S343G	Neutral	0.063
USH2A	O75445-1.3	S343H	Neutral	0.079
USH2A	O75445-1.3	S343I	Neutral	0.27
USH2A	O75445-1.3	S343K	Neutral	0.031
USH2A	O75445-1.3	S343L	Neutral	0.26
USH2A	O75445-1.3	S343M	Neutral	0.109
USH2A	O75445-1.3	S343N	Neutral	0.039
USH2A	O75445-1.3	S343P	Neutral	0.22
USH2A	O75445-1.3	S343Q	Neutral	0.041
USH2A	O75445-1.3	S343R	Neutral	0.046
USH2A	O75445-1.3	S343T	Neutral	0.038
USH2A	O75445-1.3	S343V	Neutral	0.338
USH2A	O75445-1.3	S343W	Neutral	0.232
USH2A	O75445-1.3	S343Y	Neutral	0.124
USH2A	O75445-1.3	F344A	Pathogenic	0.69
USH2A	O75445-1.3	F344C	Pathogenic	0.746
USH2A	O75445-1.3	F344D	Pathogenic	0.949
USH2A	O75445-1.3	F344E	Pathogenic	0.969
USH2A	O75445-1.3	F344G	Pathogenic	0.763
USH2A	O75445-1.3	F344H	Pathogenic	0.846
USH2A	O75445-1.3	F344I	Pathogenic	0.562
USH2A	O75445-1.3	F344K	Pathogenic	0.989
USH2A	O75445-1.3	F344L	Pathogenic	0.571
USH2A	O75445-1.3	F344M	Pathogenic	0.627
USH2A	O75445-1.3	F344N	Pathogenic	0.953
USH2A	O75445-1.3	F344P	Pathogenic	0.952
USH2A	O75445-1.3	F344Q	Pathogenic	0.968
USH2A	O75445-1.3	F344R	Pathogenic	0.983
USH2A	O75445-1.3	F344S	Pathogenic	0.762
USH2A	O75445-1.3	F344T	Pathogenic	0.84
USH2A	O75445-1.3	F344V	Pathogenic	0.678
USH2A	O75445-1.3	F344W	Neutral	0.289
USH2A	O75445-1.3	F344Y	Neutral	0.16
USH2A	O75445-1.3	V345A	Neutral	0.093
USH2A	O75445-1.3	V345C	Neutral	0.237
USH2A	O75445-1.3	V345D	Pathogenic	0.819
USH2A	O75445-1.3	V345E	Pathogenic	0.719
USH2A	O75445-1.3	V345F	Neutral	0.205
USH2A	O75445-1.3	V345G	Neutral	0.437
USH2A	O75445-1.3	V345H	Pathogenic	0.749
USH2A	O75445-1.3	V345I	Neutral	0.013
USH2A	O75445-1.3	V345K	Pathogenic	0.57
USH2A	O75445-1.3	V345L	Neutral	0.063
USH2A	O75445-1.3	V345M	Neutral	0.051
USH2A	O75445-1.3	V345N	Pathogenic	0.83
USH2A	O75445-1.3	V345P	Neutral	0.478
USH2A	O75445-1.3	V345Q	Pathogenic	0.639
USH2A	O75445-1.3	V345R	Pathogenic	0.667
USH2A	O75445-1.3	V345S	Neutral	0.436
USH2A	O75445-1.3	V345T	Neutral	0.196
USH2A	O75445-1.3	V345W	Neutral	0.407
USH2A	O75445-1.3	V345Y	Neutral	0.154
USH2A	O75445-1.3	N346A	Pathogenic	0.986
USH2A	O75445-1.3	N346C	Pathogenic	0.998
USH2A	O75445-1.3	N346D	Pathogenic	0.896
USH2A	O75445-1.3	N346E	Pathogenic	0.934
USH2A	O75445-1.3	N346F	Pathogenic	0.996
USH2A	O75445-1.3	N346G	Pathogenic	0.86
USH2A	O75445-1.3	N346H	Pathogenic	0.869
USH2A	O75445-1.3	N346I	Pathogenic	0.997
USH2A	O75445-1.3	N346K	Pathogenic	0.881
USH2A	O75445-1.3	N346L	Pathogenic	0.997
USH2A	O75445-1.3	N346M	Pathogenic	0.991
USH2A	O75445-1.3	N346P	Pathogenic	0.994
USH2A	O75445-1.3	N346Q	Pathogenic	0.935
USH2A	O75445-1.3	N346R	Pathogenic	0.83
USH2A	O75445-1.3	N346S	Pathogenic	0.855
USH2A	O75445-1.3	N346T	Pathogenic	0.967
USH2A	O75445-1.3	N346V	Pathogenic	0.998
USH2A	O75445-1.3	N346W	Pathogenic	0.996
USH2A	O75445-1.3	N346Y	Pathogenic	0.983
USH2A	O75445-1.3	D347A	Pathogenic	0.991
USH2A	O75445-1.3	D347C	Pathogenic	0.999
USH2A	O75445-1.3	D347E	Pathogenic	0.765
USH2A	O75445-1.3	D347F	Pathogenic	0.997
USH2A	O75445-1.3	D347G	Pathogenic	0.96
USH2A	O75445-1.3	D347H	Pathogenic	0.977
USH2A	O75445-1.3	D347I	Pathogenic	0.998
USH2A	O75445-1.3	D347K	Pathogenic	0.946
USH2A	O75445-1.3	D347L	Pathogenic	0.999
USH2A	O75445-1.3	D347M	Pathogenic	0.997
USH2A	O75445-1.3	D347N	Pathogenic	0.92
USH2A	O75445-1.3	D347P	Pathogenic	0.992
USH2A	O75445-1.3	D347Q	Pathogenic	0.947
USH2A	O75445-1.3	D347R	Pathogenic	0.964
USH2A	O75445-1.3	D347S	Pathogenic	0.958
USH2A	O75445-1.3	D347T	Pathogenic	0.99
USH2A	O75445-1.3	D347V	Pathogenic	0.998
USH2A	O75445-1.3	D347W	Pathogenic	0.997
USH2A	O75445-1.3	D347Y	Pathogenic	0.994
USH2A	O75445-1.3	N348A	Pathogenic	0.54
USH2A	O75445-1.3	N348C	Pathogenic	0.874
USH2A	O75445-1.3	N348D	Neutral	0.129
USH2A	O75445-1.3	N348E	Neutral	0.196
USH2A	O75445-1.3	N348F	Pathogenic	0.802
USH2A	O75445-1.3	N348G	Neutral	0.095
USH2A	O75445-1.3	N348H	Neutral	0.102
USH2A	O75445-1.3	N348I	Pathogenic	0.853
USH2A	O75445-1.3	N348K	Neutral	0.112
USH2A	O75445-1.3	N348L	Pathogenic	0.847
USH2A	O75445-1.3	N348M	Pathogenic	0.658
USH2A	O75445-1.3	N348P	Pathogenic	0.751
USH2A	O75445-1.3	N348Q	Neutral	0.198
USH2A	O75445-1.3	N348R	Neutral	0.077
USH2A	O75445-1.3	N348S	Neutral	0.092
USH2A	O75445-1.3	N348T	Neutral	0.336
USH2A	O75445-1.3	N348V	Pathogenic	0.889
USH2A	O75445-1.3	N348W	Pathogenic	0.826
USH2A	O75445-1.3	N348Y	Neutral	0.493
USH2A	O75445-1.3	D349A	Pathogenic	0.966
USH2A	O75445-1.3	D349C	Pathogenic	0.994
USH2A	O75445-1.3	D349E	Neutral	0.44
USH2A	O75445-1.3	D349F	Pathogenic	0.986
USH2A	O75445-1.3	D349G	Pathogenic	0.852
USH2A	O75445-1.3	D349H	Pathogenic	0.911
USH2A	O75445-1.3	D349I	Pathogenic	0.99
USH2A	O75445-1.3	D349K	Pathogenic	0.809
USH2A	O75445-1.3	D349L	Pathogenic	0.995
USH2A	O75445-1.3	D349M	Pathogenic	0.987
USH2A	O75445-1.3	D349N	Pathogenic	0.735
USH2A	O75445-1.3	D349P	Pathogenic	0.969
USH2A	O75445-1.3	D349Q	Pathogenic	0.811
USH2A	O75445-1.3	D349R	Pathogenic	0.865
USH2A	O75445-1.3	D349S	Pathogenic	0.847
USH2A	O75445-1.3	D349T	Pathogenic	0.961
USH2A	O75445-1.3	D349V	Pathogenic	0.993
USH2A	O75445-1.3	D349W	Pathogenic	0.988
USH2A	O75445-1.3	D349Y	Pathogenic	0.975
USH2A	O75445-1.3	V350A	Neutral	0.019
USH2A	O75445-1.3	V350C	Neutral	0.054
USH2A	O75445-1.3	V350D	Neutral	0.456
USH2A	O75445-1.3	V350E	Neutral	0.321
USH2A	O75445-1.3	V350F	Neutral	0.045
USH2A	O75445-1.3	V350G	Neutral	0.126
USH2A	O75445-1.3	V350H	Neutral	0.356
USH2A	O75445-1.3	V350I	Neutral	0.003
USH2A	O75445-1.3	V350K	Neutral	0.197
USH2A	O75445-1.3	V350L	Neutral	0.012
USH2A	O75445-1.3	V350M	Neutral	0.01
USH2A	O75445-1.3	V350N	Neutral	0.475
USH2A	O75445-1.3	V350P	Neutral	0.145
USH2A	O75445-1.3	V350Q	Neutral	0.247
USH2A	O75445-1.3	V350R	Neutral	0.27
USH2A	O75445-1.3	V350S	Neutral	0.125
USH2A	O75445-1.3	V350T	Neutral	0.043
USH2A	O75445-1.3	V350W	Neutral	0.113
USH2A	O75445-1.3	V350Y	Neutral	0.032
USH2A	O75445-1.3	G351A	Neutral	0.365
USH2A	O75445-1.3	G351C	Pathogenic	0.839
USH2A	O75445-1.3	G351D	Neutral	0.433
USH2A	O75445-1.3	G351E	Neutral	0.478
USH2A	O75445-1.3	G351F	Pathogenic	0.617
USH2A	O75445-1.3	G351H	Neutral	0.348
USH2A	O75445-1.3	G351I	Pathogenic	0.841
USH2A	O75445-1.3	G351K	Neutral	0.322
USH2A	O75445-1.3	G351L	Pathogenic	0.834
USH2A	O75445-1.3	G351M	Pathogenic	0.635
USH2A	O75445-1.3	G351N	Neutral	0.208
USH2A	O75445-1.3	G351P	Pathogenic	0.637
USH2A	O75445-1.3	G351Q	Neutral	0.388
USH2A	O75445-1.3	G351R	Neutral	0.239
USH2A	O75445-1.3	G351S	Neutral	0.293
USH2A	O75445-1.3	G351T	Pathogenic	0.559
USH2A	O75445-1.3	G351V	Pathogenic	0.761
USH2A	O75445-1.3	G351W	Neutral	0.265
USH2A	O75445-1.3	G351Y	Neutral	0.468
USH2A	O75445-1.3	T352A	Pathogenic	0.692
USH2A	O75445-1.3	T352C	Pathogenic	0.93
USH2A	O75445-1.3	T352D	Pathogenic	0.947
USH2A	O75445-1.3	T352E	Pathogenic	0.915
USH2A	O75445-1.3	T352F	Pathogenic	0.936
USH2A	O75445-1.3	T352G	Pathogenic	0.876
USH2A	O75445-1.3	T352H	Pathogenic	0.926
USH2A	O75445-1.3	T352I	Pathogenic	0.902
USH2A	O75445-1.3	T352K	Pathogenic	0.847
USH2A	O75445-1.3	T352L	Pathogenic	0.897
USH2A	O75445-1.3	T352M	Pathogenic	0.874
USH2A	O75445-1.3	T352N	Pathogenic	0.875
USH2A	O75445-1.3	T352P	Pathogenic	0.929
USH2A	O75445-1.3	T352Q	Pathogenic	0.881
USH2A	O75445-1.3	T352R	Pathogenic	0.787
USH2A	O75445-1.3	T352S	Pathogenic	0.574
USH2A	O75445-1.3	T352V	Pathogenic	0.847
USH2A	O75445-1.3	T352W	Pathogenic	0.882
USH2A	O75445-1.3	T352Y	Pathogenic	0.889
USH2A	O75445-1.3	S353A	Neutral	0.084
USH2A	O75445-1.3	S353C	Neutral	0.349
USH2A	O75445-1.3	S353D	Neutral	0.148
USH2A	O75445-1.3	S353E	Neutral	0.084
USH2A	O75445-1.3	S353F	Neutral	0.275
USH2A	O75445-1.3	S353G	Neutral	0.089
USH2A	O75445-1.3	S353H	Neutral	0.112
USH2A	O75445-1.3	S353I	Neutral	0.352
USH2A	O75445-1.3	S353K	Neutral	0.045
USH2A	O75445-1.3	S353L	Neutral	0.341
USH2A	O75445-1.3	S353M	Neutral	0.152
USH2A	O75445-1.3	S353N	Neutral	0.056
USH2A	O75445-1.3	S353P	Neutral	0.293
USH2A	O75445-1.3	S353Q	Neutral	0.059
USH2A	O75445-1.3	S353R	Neutral	0.067
USH2A	O75445-1.3	S353T	Neutral	0.054
USH2A	O75445-1.3	S353V	Neutral	0.428
USH2A	O75445-1.3	S353W	Neutral	0.307
USH2A	O75445-1.3	S353Y	Neutral	0.172
USH2A	O75445-1.3	W354A	Pathogenic	0.989
USH2A	O75445-1.3	W354C	Pathogenic	0.981
USH2A	O75445-1.3	W354D	Pathogenic	0.999
USH2A	O75445-1.3	W354E	Pathogenic	0.998
USH2A	O75445-1.3	W354F	Pathogenic	0.932
USH2A	O75445-1.3	W354G	Pathogenic	0.961
USH2A	O75445-1.3	W354H	Pathogenic	0.995
USH2A	O75445-1.3	W354I	Pathogenic	0.996
USH2A	O75445-1.3	W354K	Pathogenic	0.999
USH2A	O75445-1.3	W354L	Pathogenic	0.992
USH2A	O75445-1.3	W354M	Pathogenic	0.985
USH2A	O75445-1.3	W354N	Pathogenic	0.999
USH2A	O75445-1.3	W354P	Pathogenic	0.997
USH2A	O75445-1.3	W354Q	Pathogenic	0.996
USH2A	O75445-1.3	W354R	Pathogenic	1.0
USH2A	O75445-1.3	W354S	Pathogenic	0.992
USH2A	O75445-1.3	W354T	Pathogenic	0.989
USH2A	O75445-1.3	W354V	Pathogenic	0.995
USH2A	O75445-1.3	W354Y	Pathogenic	0.917
USH2A	O75445-1.3	V355A	Neutral	0.125
USH2A	O75445-1.3	V355C	Neutral	0.3
USH2A	O75445-1.3	V355D	Pathogenic	0.862
USH2A	O75445-1.3	V355E	Pathogenic	0.78
USH2A	O75445-1.3	V355F	Neutral	0.262
USH2A	O75445-1.3	V355G	Pathogenic	0.517
USH2A	O75445-1.3	V355H	Pathogenic	0.805
USH2A	O75445-1.3	V355I	Neutral	0.018
USH2A	O75445-1.3	V355K	Pathogenic	0.646
USH2A	O75445-1.3	V355L	Neutral	0.085
USH2A	O75445-1.3	V355M	Neutral	0.069
USH2A	O75445-1.3	V355N	Pathogenic	0.871
USH2A	O75445-1.3	V355P	Pathogenic	0.559
USH2A	O75445-1.3	V355Q	Pathogenic	0.71
USH2A	O75445-1.3	V355R	Pathogenic	0.735
USH2A	O75445-1.3	V355S	Pathogenic	0.516
USH2A	O75445-1.3	V355T	Neutral	0.252
USH2A	O75445-1.3	V355W	Neutral	0.487
USH2A	O75445-1.3	V355Y	Neutral	0.2
USH2A	O75445-1.3	S356A	Pathogenic	0.822
USH2A	O75445-1.3	S356C	Pathogenic	0.964
USH2A	O75445-1.3	S356D	Pathogenic	0.897
USH2A	O75445-1.3	S356E	Pathogenic	0.82
USH2A	O75445-1.3	S356F	Pathogenic	0.95
USH2A	O75445-1.3	S356G	Pathogenic	0.831
USH2A	O75445-1.3	S356H	Pathogenic	0.863
USH2A	O75445-1.3	S356I	Pathogenic	0.965
USH2A	O75445-1.3	S356K	Pathogenic	0.702
USH2A	O75445-1.3	S356L	Pathogenic	0.963
USH2A	O75445-1.3	S356M	Pathogenic	0.9
USH2A	O75445-1.3	S356N	Pathogenic	0.749
USH2A	O75445-1.3	S356P	Pathogenic	0.954
USH2A	O75445-1.3	S356Q	Pathogenic	0.76
USH2A	O75445-1.3	S356R	Pathogenic	0.781
USH2A	O75445-1.3	S356T	Pathogenic	0.742
USH2A	O75445-1.3	S356V	Pathogenic	0.974
USH2A	O75445-1.3	S356W	Pathogenic	0.957
USH2A	O75445-1.3	S356Y	Pathogenic	0.912
USH2A	O75445-1.3	N357A	Neutral	0.021
USH2A	O75445-1.3	N357C	Neutral	0.114
USH2A	O75445-1.3	N357D	Neutral	0.003
USH2A	O75445-1.3	N357E	Neutral	0.005
USH2A	O75445-1.3	N357F	Neutral	0.07
USH2A	O75445-1.3	N357G	Neutral	0.002
USH2A	O75445-1.3	N357H	Neutral	0.002
USH2A	O75445-1.3	N357I	Neutral	0.098
USH2A	O75445-1.3	N357K	Neutral	0.002
USH2A	O75445-1.3	N357L	Neutral	0.093
USH2A	O75445-1.3	N357M	Neutral	0.034
USH2A	O75445-1.3	N357P	Neutral	0.053
USH2A	O75445-1.3	N357Q	Neutral	0.005
USH2A	O75445-1.3	N357R	Neutral	0.002
USH2A	O75445-1.3	N357S	Neutral	0.002
USH2A	O75445-1.3	N357T	Neutral	0.009
USH2A	O75445-1.3	N357V	Neutral	0.13
USH2A	O75445-1.3	N357W	Neutral	0.081
USH2A	O75445-1.3	N357Y	Neutral	0.018
USH2A	O75445-1.3	V358A	Neutral	0.385
USH2A	O75445-1.3	V358C	Pathogenic	0.653
USH2A	O75445-1.3	V358D	Pathogenic	0.965
USH2A	O75445-1.3	V358E	Pathogenic	0.94
USH2A	O75445-1.3	V358F	Pathogenic	0.61
USH2A	O75445-1.3	V358G	Pathogenic	0.825
USH2A	O75445-1.3	V358H	Pathogenic	0.948
USH2A	O75445-1.3	V358I	Neutral	0.076
USH2A	O75445-1.3	V358K	Pathogenic	0.889
USH2A	O75445-1.3	V358L	Neutral	0.29
USH2A	O75445-1.3	V358M	Neutral	0.245
USH2A	O75445-1.3	V358N	Pathogenic	0.967
USH2A	O75445-1.3	V358P	Pathogenic	0.848
USH2A	O75445-1.3	V358Q	Pathogenic	0.915
USH2A	O75445-1.3	V358R	Pathogenic	0.924
USH2A	O75445-1.3	V358S	Pathogenic	0.825
USH2A	O75445-1.3	V358T	Pathogenic	0.597
USH2A	O75445-1.3	V358W	Pathogenic	0.807
USH2A	O75445-1.3	V358Y	Pathogenic	0.525
USH2A	O75445-1.3	F359A	Pathogenic	0.645
USH2A	O75445-1.3	F359C	Pathogenic	0.705
USH2A	O75445-1.3	F359D	Pathogenic	0.939
USH2A	O75445-1.3	F359E	Pathogenic	0.962
USH2A	O75445-1.3	F359G	Pathogenic	0.724
USH2A	O75445-1.3	F359H	Pathogenic	0.817
USH2A	O75445-1.3	F359I	Pathogenic	0.511
USH2A	O75445-1.3	F359K	Pathogenic	0.986
USH2A	O75445-1.3	F359L	Pathogenic	0.521
USH2A	O75445-1.3	F359M	Pathogenic	0.578
USH2A	O75445-1.3	F359N	Pathogenic	0.943
USH2A	O75445-1.3	F359P	Pathogenic	0.942
USH2A	O75445-1.3	F359Q	Pathogenic	0.961
USH2A	O75445-1.3	F359R	Pathogenic	0.979
USH2A	O75445-1.3	F359S	Pathogenic	0.723
USH2A	O75445-1.3	F359T	Pathogenic	0.811
USH2A	O75445-1.3	F359V	Pathogenic	0.631
USH2A	O75445-1.3	F359W	Neutral	0.249
USH2A	O75445-1.3	F359Y	Neutral	0.134
USH2A	O75445-1.3	T360A	Neutral	0.03
USH2A	O75445-1.3	T360C	Neutral	0.156
USH2A	O75445-1.3	T360D	Neutral	0.201
USH2A	O75445-1.3	T360E	Neutral	0.131
USH2A	O75445-1.3	T360F	Neutral	0.17
USH2A	O75445-1.3	T360G	Neutral	0.09
USH2A	O75445-1.3	T360H	Neutral	0.149
USH2A	O75445-1.3	T360I	Neutral	0.114
USH2A	O75445-1.3	T360K	Neutral	0.072
USH2A	O75445-1.3	T360L	Neutral	0.109
USH2A	O75445-1.3	T360M	Neutral	0.088
USH2A	O75445-1.3	T360N	Neutral	0.089
USH2A	O75445-1.3	T360P	Neutral	0.156
USH2A	O75445-1.3	T360Q	Neutral	0.094
USH2A	O75445-1.3	T360R	Neutral	0.049
USH2A	O75445-1.3	T360S	Neutral	0.018
USH2A	O75445-1.3	T360V	Neutral	0.072
USH2A	O75445-1.3	T360W	Neutral	0.095
USH2A	O75445-1.3	T360Y	Neutral	0.101
USH2A	O75445-1.3	N361A	Neutral	0.074
USH2A	O75445-1.3	N361C	Neutral	0.321
USH2A	O75445-1.3	N361D	Neutral	0.01
USH2A	O75445-1.3	N361E	Neutral	0.016
USH2A	O75445-1.3	N361F	Neutral	0.217
USH2A	O75445-1.3	N361G	Neutral	0.007
USH2A	O75445-1.3	N361H	Neutral	0.008
USH2A	O75445-1.3	N361I	Neutral	0.285
USH2A	O75445-1.3	N361K	Neutral	0.009
USH2A	O75445-1.3	N361L	Neutral	0.275
USH2A	O75445-1.3	N361M	Neutral	0.116
USH2A	O75445-1.3	N361P	Neutral	0.171
USH2A	O75445-1.3	N361Q	Neutral	0.017
USH2A	O75445-1.3	N361R	Neutral	0.006
USH2A	O75445-1.3	N361S	Neutral	0.007
USH2A	O75445-1.3	N361T	Neutral	0.033
USH2A	O75445-1.3	N361V	Neutral	0.354
USH2A	O75445-1.3	N361W	Neutral	0.245
USH2A	O75445-1.3	N361Y	Neutral	0.062
USH2A	O75445-1.3	I362A	Neutral	0.02
USH2A	O75445-1.3	I362C	Neutral	0.026
USH2A	O75445-1.3	I362D	Neutral	0.28
USH2A	O75445-1.3	I362E	Neutral	0.393
USH2A	O75445-1.3	I362F	Neutral	0.018
USH2A	O75445-1.3	I362G	Neutral	0.132
USH2A	O75445-1.3	I362H	Neutral	0.371
USH2A	O75445-1.3	I362K	Neutral	0.467
USH2A	O75445-1.3	I362L	Neutral	0.005
USH2A	O75445-1.3	I362M	Neutral	0.015
USH2A	O75445-1.3	I362N	Neutral	0.295
USH2A	O75445-1.3	I362P	Neutral	0.152
USH2A	O75445-1.3	I362Q	Neutral	0.382
USH2A	O75445-1.3	I362R	Neutral	0.368
USH2A	O75445-1.3	I362S	Neutral	0.062
USH2A	O75445-1.3	I362T	Neutral	0.045
USH2A	O75445-1.3	I362V	Neutral	0.002
USH2A	O75445-1.3	I362W	Neutral	0.1
USH2A	O75445-1.3	I362Y	Neutral	0.05
USH2A	O75445-1.3	T363A	Neutral	0.027
USH2A	O75445-1.3	T363C	Neutral	0.142
USH2A	O75445-1.3	T363D	Neutral	0.184
USH2A	O75445-1.3	T363E	Neutral	0.119
USH2A	O75445-1.3	T363F	Neutral	0.155
USH2A	O75445-1.3	T363G	Neutral	0.081
USH2A	O75445-1.3	T363H	Neutral	0.136
USH2A	O75445-1.3	T363I	Neutral	0.103
USH2A	O75445-1.3	T363K	Neutral	0.065
USH2A	O75445-1.3	T363L	Neutral	0.098
USH2A	O75445-1.3	T363M	Neutral	0.08
USH2A	O75445-1.3	T363N	Neutral	0.081
USH2A	O75445-1.3	T363P	Neutral	0.142
USH2A	O75445-1.3	T363Q	Neutral	0.085
USH2A	O75445-1.3	T363R	Neutral	0.044
USH2A	O75445-1.3	T363S	Neutral	0.017
USH2A	O75445-1.3	T363V	Neutral	0.065
USH2A	O75445-1.3	T363W	Neutral	0.086
USH2A	O75445-1.3	T363Y	Neutral	0.091
USH2A	O75445-1.3	Q364A	Neutral	0.082
USH2A	O75445-1.3	Q364C	Pathogenic	0.544
USH2A	O75445-1.3	Q364D	Neutral	0.078
USH2A	O75445-1.3	Q364E	Neutral	0.027
USH2A	O75445-1.3	Q364F	Pathogenic	0.69
USH2A	O75445-1.3	Q364G	Neutral	0.086
USH2A	O75445-1.3	Q364H	Neutral	0.124
USH2A	O75445-1.3	Q364I	Pathogenic	0.762
USH2A	O75445-1.3	Q364K	Neutral	0.042
USH2A	O75445-1.3	Q364L	Pathogenic	0.571
USH2A	O75445-1.3	Q364M	Neutral	0.168
USH2A	O75445-1.3	Q364N	Neutral	0.084
USH2A	O75445-1.3	Q364P	Neutral	0.186
USH2A	O75445-1.3	Q364R	Neutral	0.029
USH2A	O75445-1.3	Q364S	Neutral	0.038
USH2A	O75445-1.3	Q364T	Neutral	0.166
USH2A	O75445-1.3	Q364V	Pathogenic	0.519
USH2A	O75445-1.3	Q364W	Neutral	0.333
USH2A	O75445-1.3	Q364Y	Neutral	0.189
USH2A	O75445-1.3	L365A	Pathogenic	0.777
USH2A	O75445-1.3	L365C	Pathogenic	0.821
USH2A	O75445-1.3	L365D	Pathogenic	0.994
USH2A	O75445-1.3	L365E	Pathogenic	0.991
USH2A	O75445-1.3	L365F	Pathogenic	0.777
USH2A	O75445-1.3	L365G	Pathogenic	0.963
USH2A	O75445-1.3	L365H	Pathogenic	0.99
USH2A	O75445-1.3	L365I	Neutral	0.49
USH2A	O75445-1.3	L365K	Pathogenic	0.985
USH2A	O75445-1.3	L365M	Pathogenic	0.535
USH2A	O75445-1.3	L365N	Pathogenic	0.986
USH2A	O75445-1.3	L365P	Pathogenic	0.969
USH2A	O75445-1.3	L365Q	Pathogenic	0.979
USH2A	O75445-1.3	L365R	Pathogenic	0.978
USH2A	O75445-1.3	L365S	Pathogenic	0.92
USH2A	O75445-1.3	L365T	Pathogenic	0.892
USH2A	O75445-1.3	L365V	Pathogenic	0.59
USH2A	O75445-1.3	L365W	Pathogenic	0.903
USH2A	O75445-1.3	L365Y	Pathogenic	0.901
USH2A	O75445-1.3	N366A	Neutral	0.254
USH2A	O75445-1.3	N366C	Pathogenic	0.667
USH2A	O75445-1.3	N366D	Neutral	0.041
USH2A	O75445-1.3	N366E	Neutral	0.066
USH2A	O75445-1.3	N366F	Pathogenic	0.541
USH2A	O75445-1.3	N366G	Neutral	0.03
USH2A	O75445-1.3	N366H	Neutral	0.032
USH2A	O75445-1.3	N366I	Pathogenic	0.628
USH2A	O75445-1.3	N366K	Neutral	0.035
USH2A	O75445-1.3	N366L	Pathogenic	0.616
USH2A	O75445-1.3	N366M	Neutral	0.358
USH2A	O75445-1.3	N366P	Neutral	0.467
USH2A	O75445-1.3	N366Q	Neutral	0.067
USH2A	O75445-1.3	N366R	Neutral	0.024
USH2A	O75445-1.3	N366S	Neutral	0.028
USH2A	O75445-1.3	N366T	Neutral	0.128
USH2A	O75445-1.3	N366V	Pathogenic	0.699
USH2A	O75445-1.3	N366W	Pathogenic	0.579
USH2A	O75445-1.3	N366Y	Neutral	0.22
USH2A	O75445-1.3	Q367A	Neutral	0.022
USH2A	O75445-1.3	Q367C	Neutral	0.228
USH2A	O75445-1.3	Q367D	Neutral	0.021
USH2A	O75445-1.3	Q367E	Neutral	0.007
USH2A	O75445-1.3	Q367F	Neutral	0.356
USH2A	O75445-1.3	Q367G	Neutral	0.023
USH2A	O75445-1.3	Q367H	Neutral	0.034
USH2A	O75445-1.3	Q367I	Neutral	0.442
USH2A	O75445-1.3	Q367K	Neutral	0.011
USH2A	O75445-1.3	Q367L	Neutral	0.248
USH2A	O75445-1.3	Q367M	Neutral	0.048
USH2A	O75445-1.3	Q367N	Neutral	0.022
USH2A	O75445-1.3	Q367P	Neutral	0.054
USH2A	O75445-1.3	Q367R	Neutral	0.007
USH2A	O75445-1.3	Q367S	Neutral	0.01
USH2A	O75445-1.3	Q367T	Neutral	0.047
USH2A	O75445-1.3	Q367V	Neutral	0.211
USH2A	O75445-1.3	Q367W	Neutral	0.11
USH2A	O75445-1.3	Q367Y	Neutral	0.055
USH2A	O75445-1.3	G368A	Pathogenic	0.74
USH2A	O75445-1.3	G368C	Pathogenic	0.963
USH2A	O75445-1.3	G368D	Pathogenic	0.791
USH2A	O75445-1.3	G368E	Pathogenic	0.82
USH2A	O75445-1.3	G368F	Pathogenic	0.889
USH2A	O75445-1.3	G368H	Pathogenic	0.726
USH2A	O75445-1.3	G368I	Pathogenic	0.963
USH2A	O75445-1.3	G368K	Pathogenic	0.701
USH2A	O75445-1.3	G368L	Pathogenic	0.961
USH2A	O75445-1.3	G368M	Pathogenic	0.896
USH2A	O75445-1.3	G368N	Pathogenic	0.565
USH2A	O75445-1.3	G368P	Pathogenic	0.897
USH2A	O75445-1.3	G368Q	Pathogenic	0.759
USH2A	O75445-1.3	G368R	Pathogenic	0.609
USH2A	O75445-1.3	G368S	Pathogenic	0.673
USH2A	O75445-1.3	G368T	Pathogenic	0.863
USH2A	O75445-1.3	G368V	Pathogenic	0.94
USH2A	O75445-1.3	G368W	Pathogenic	0.641
USH2A	O75445-1.3	G368Y	Pathogenic	0.813
USH2A	O75445-1.3	V369A	Pathogenic	0.592
USH2A	O75445-1.3	V369C	Pathogenic	0.813
USH2A	O75445-1.3	V369D	Pathogenic	0.985
USH2A	O75445-1.3	V369E	Pathogenic	0.973
USH2A	O75445-1.3	V369F	Pathogenic	0.783
USH2A	O75445-1.3	V369G	Pathogenic	0.916
USH2A	O75445-1.3	V369H	Pathogenic	0.977
USH2A	O75445-1.3	V369I	Neutral	0.16
USH2A	O75445-1.3	V369K	Pathogenic	0.949
USH2A	O75445-1.3	V369L	Neutral	0.486
USH2A	O75445-1.3	V369M	Neutral	0.428
USH2A	O75445-1.3	V369N	Pathogenic	0.986
USH2A	O75445-1.3	V369P	Pathogenic	0.928
USH2A	O75445-1.3	V369Q	Pathogenic	0.961
USH2A	O75445-1.3	V369R	Pathogenic	0.966
USH2A	O75445-1.3	V369S	Pathogenic	0.916
USH2A	O75445-1.3	V369T	Pathogenic	0.774
USH2A	O75445-1.3	V369W	Pathogenic	0.906
USH2A	O75445-1.3	V369Y	Pathogenic	0.718
USH2A	O75445-1.3	T370A	Neutral	0.236
USH2A	O75445-1.3	T370C	Pathogenic	0.644
USH2A	O75445-1.3	T370D	Pathogenic	0.712
USH2A	O75445-1.3	T370E	Pathogenic	0.596
USH2A	O75445-1.3	T370F	Pathogenic	0.667
USH2A	O75445-1.3	T370G	Neutral	0.492
USH2A	O75445-1.3	T370H	Pathogenic	0.633
USH2A	O75445-1.3	T370I	Pathogenic	0.558
USH2A	O75445-1.3	T370K	Neutral	0.433
USH2A	O75445-1.3	T370L	Pathogenic	0.545
USH2A	O75445-1.3	T370M	Neutral	0.487
USH2A	O75445-1.3	T370N	Neutral	0.491
USH2A	O75445-1.3	T370P	Pathogenic	0.644
USH2A	O75445-1.3	T370Q	Pathogenic	0.505
USH2A	O75445-1.3	T370R	Neutral	0.336
USH2A	O75445-1.3	T370S	Neutral	0.156
USH2A	O75445-1.3	T370V	Neutral	0.432
USH2A	O75445-1.3	T370W	Pathogenic	0.507
USH2A	O75445-1.3	T370Y	Pathogenic	0.523
USH2A	O75445-1.3	I371A	Pathogenic	0.781
USH2A	O75445-1.3	I371C	Pathogenic	0.825
USH2A	O75445-1.3	I371D	Pathogenic	0.986
USH2A	O75445-1.3	I371E	Pathogenic	0.991
USH2A	O75445-1.3	I371F	Pathogenic	0.767
USH2A	O75445-1.3	I371G	Pathogenic	0.964
USH2A	O75445-1.3	I371H	Pathogenic	0.991
USH2A	O75445-1.3	I371K	Pathogenic	0.994
USH2A	O75445-1.3	I371L	Neutral	0.484
USH2A	O75445-1.3	I371M	Pathogenic	0.73
USH2A	O75445-1.3	I371N	Pathogenic	0.987
USH2A	O75445-1.3	I371P	Pathogenic	0.97
USH2A	O75445-1.3	I371Q	Pathogenic	0.991
USH2A	O75445-1.3	I371R	Pathogenic	0.99
USH2A	O75445-1.3	I371S	Pathogenic	0.922
USH2A	O75445-1.3	I371T	Pathogenic	0.894
USH2A	O75445-1.3	I371V	Neutral	0.221
USH2A	O75445-1.3	I371W	Pathogenic	0.952
USH2A	O75445-1.3	I371Y	Pathogenic	0.903
USH2A	O75445-1.3	S372A	Neutral	0.116
USH2A	O75445-1.3	S372C	Neutral	0.433
USH2A	O75445-1.3	S372D	Neutral	0.198
USH2A	O75445-1.3	S372E	Neutral	0.115
USH2A	O75445-1.3	S372F	Neutral	0.35
USH2A	O75445-1.3	S372G	Neutral	0.122
USH2A	O75445-1.3	S372H	Neutral	0.152
USH2A	O75445-1.3	S372I	Neutral	0.436
USH2A	O75445-1.3	S372K	Neutral	0.063
USH2A	O75445-1.3	S372L	Neutral	0.424
USH2A	O75445-1.3	S372M	Neutral	0.203
USH2A	O75445-1.3	S372N	Neutral	0.078
USH2A	O75445-1.3	S372P	Neutral	0.371
USH2A	O75445-1.3	S372Q	Neutral	0.082
USH2A	O75445-1.3	S372R	Neutral	0.092
USH2A	O75445-1.3	S372T	Neutral	0.075
USH2A	O75445-1.3	S372V	Pathogenic	0.515
USH2A	O75445-1.3	S372W	Neutral	0.387
USH2A	O75445-1.3	S372Y	Neutral	0.228
USH2A	O75445-1.3	V373A	Neutral	0.074
USH2A	O75445-1.3	V373C	Neutral	0.194
USH2A	O75445-1.3	V373D	Pathogenic	0.779
USH2A	O75445-1.3	V373E	Pathogenic	0.666
USH2A	O75445-1.3	V373F	Neutral	0.167
USH2A	O75445-1.3	V373G	Neutral	0.377
USH2A	O75445-1.3	V373H	Pathogenic	0.699
USH2A	O75445-1.3	V373I	Neutral	0.01
USH2A	O75445-1.3	V373K	Pathogenic	0.508
USH2A	O75445-1.3	V373L	Neutral	0.05
USH2A	O75445-1.3	V373M	Neutral	0.04
USH2A	O75445-1.3	V373N	Pathogenic	0.792
USH2A	O75445-1.3	V373P	Neutral	0.417
USH2A	O75445-1.3	V373Q	Pathogenic	0.58
USH2A	O75445-1.3	V373R	Pathogenic	0.61
USH2A	O75445-1.3	V373S	Neutral	0.376
USH2A	O75445-1.3	V373T	Neutral	0.159
USH2A	O75445-1.3	V373W	Neutral	0.348
USH2A	O75445-1.3	V373Y	Neutral	0.124
USH2A	O75445-1.3	D374A	Pathogenic	0.989
USH2A	O75445-1.3	D374C	Pathogenic	0.998
USH2A	O75445-1.3	D374E	Pathogenic	0.717
USH2A	O75445-1.3	D374F	Pathogenic	0.996
USH2A	O75445-1.3	D374G	Pathogenic	0.949
USH2A	O75445-1.3	D374H	Pathogenic	0.971
USH2A	O75445-1.3	D374I	Pathogenic	0.997
USH2A	O75445-1.3	D374K	Pathogenic	0.932
USH2A	O75445-1.3	D374L	Pathogenic	0.999
USH2A	O75445-1.3	D374M	Pathogenic	0.996
USH2A	O75445-1.3	D374N	Pathogenic	0.899
USH2A	O75445-1.3	D374P	Pathogenic	0.99
USH2A	O75445-1.3	D374Q	Pathogenic	0.933
USH2A	O75445-1.3	D374R	Pathogenic	0.954
USH2A	O75445-1.3	D374S	Pathogenic	0.947
USH2A	O75445-1.3	D374T	Pathogenic	0.987
USH2A	O75445-1.3	D374V	Pathogenic	0.998
USH2A	O75445-1.3	D374W	Pathogenic	0.996
USH2A	O75445-1.3	D374Y	Pathogenic	0.992
USH2A	O75445-1.3	L375A	Pathogenic	0.894
USH2A	O75445-1.3	L375C	Pathogenic	0.917
USH2A	O75445-1.3	L375D	Pathogenic	0.997
USH2A	O75445-1.3	L375E	Pathogenic	0.996
USH2A	O75445-1.3	L375F	Pathogenic	0.894
USH2A	O75445-1.3	L375G	Pathogenic	0.985
USH2A	O75445-1.3	L375H	Pathogenic	0.996
USH2A	O75445-1.3	L375I	Pathogenic	0.7
USH2A	O75445-1.3	L375K	Pathogenic	0.994
USH2A	O75445-1.3	L375M	Pathogenic	0.736
USH2A	O75445-1.3	L375N	Pathogenic	0.994
USH2A	O75445-1.3	L375P	Pathogenic	0.987
USH2A	O75445-1.3	L375Q	Pathogenic	0.991
USH2A	O75445-1.3	L375R	Pathogenic	0.991
USH2A	O75445-1.3	L375S	Pathogenic	0.965
USH2A	O75445-1.3	L375T	Pathogenic	0.952
USH2A	O75445-1.3	L375V	Pathogenic	0.777
USH2A	O75445-1.3	L375W	Pathogenic	0.958
USH2A	O75445-1.3	L375Y	Pathogenic	0.957
USH2A	O75445-1.3	E376A	Neutral	0.174
USH2A	O75445-1.3	E376C	Pathogenic	0.866
USH2A	O75445-1.3	E376D	Neutral	0.025
USH2A	O75445-1.3	E376F	Pathogenic	0.793
USH2A	O75445-1.3	E376G	Neutral	0.183
USH2A	O75445-1.3	E376H	Neutral	0.196
USH2A	O75445-1.3	E376I	Pathogenic	0.846
USH2A	O75445-1.3	E376K	Neutral	0.048
USH2A	O75445-1.3	E376L	Pathogenic	0.839
USH2A	O75445-1.3	E376M	Pathogenic	0.644
USH2A	O75445-1.3	E376N	Neutral	0.129
USH2A	O75445-1.3	E376P	Neutral	0.35
USH2A	O75445-1.3	E376Q	Neutral	0.043
USH2A	O75445-1.3	E376R	Neutral	0.071
USH2A	O75445-1.3	E376S	Neutral	0.086
USH2A	O75445-1.3	E376T	Neutral	0.321
USH2A	O75445-1.3	E376V	Pathogenic	0.719
USH2A	O75445-1.3	E376W	Pathogenic	0.662
USH2A	O75445-1.3	E376Y	Neutral	0.478
USH2A	O75445-1.3	N377A	Pathogenic	0.952
USH2A	O75445-1.3	N377C	Pathogenic	0.992
USH2A	O75445-1.3	N377D	Pathogenic	0.715
USH2A	O75445-1.3	N377E	Pathogenic	0.806
USH2A	O75445-1.3	N377F	Pathogenic	0.986
USH2A	O75445-1.3	N377G	Pathogenic	0.641
USH2A	O75445-1.3	N377H	Pathogenic	0.658
USH2A	O75445-1.3	N377I	Pathogenic	0.99
USH2A	O75445-1.3	N377K	Pathogenic	0.682
USH2A	O75445-1.3	N377L	Pathogenic	0.989
USH2A	O75445-1.3	N377M	Pathogenic	0.97
USH2A	O75445-1.3	N377P	Pathogenic	0.981
USH2A	O75445-1.3	N377Q	Pathogenic	0.808
USH2A	O75445-1.3	N377R	Pathogenic	0.587
USH2A	O75445-1.3	N377S	Pathogenic	0.632
USH2A	O75445-1.3	N377T	Pathogenic	0.896
USH2A	O75445-1.3	N377V	Pathogenic	0.993
USH2A	O75445-1.3	N377W	Pathogenic	0.988
USH2A	O75445-1.3	N377Y	Pathogenic	0.943
USH2A	O75445-1.3	G378A	Pathogenic	0.755
USH2A	O75445-1.3	G378C	Pathogenic	0.965
USH2A	O75445-1.3	G378D	Pathogenic	0.804
USH2A	O75445-1.3	G378E	Pathogenic	0.831
USH2A	O75445-1.3	G378F	Pathogenic	0.896
USH2A	O75445-1.3	G378H	Pathogenic	0.741
USH2A	O75445-1.3	G378I	Pathogenic	0.966
USH2A	O75445-1.3	G378K	Pathogenic	0.718
USH2A	O75445-1.3	G378L	Pathogenic	0.964
USH2A	O75445-1.3	G378M	Pathogenic	0.903
USH2A	O75445-1.3	G378N	Pathogenic	0.584
USH2A	O75445-1.3	G378P	Pathogenic	0.904
USH2A	O75445-1.3	G378Q	Pathogenic	0.773
USH2A	O75445-1.3	G378R	Pathogenic	0.628
USH2A	O75445-1.3	G378S	Pathogenic	0.69
USH2A	O75445-1.3	G378T	Pathogenic	0.872
USH2A	O75445-1.3	G378V	Pathogenic	0.945
USH2A	O75445-1.3	G378W	Pathogenic	0.659
USH2A	O75445-1.3	G378Y	Pathogenic	0.825
USH2A	O75445-1.3	Q379A	Pathogenic	0.757
USH2A	O75445-1.3	Q379C	Pathogenic	0.977
USH2A	O75445-1.3	Q379D	Pathogenic	0.749
USH2A	O75445-1.3	Q379E	Neutral	0.489
USH2A	O75445-1.3	Q379F	Pathogenic	0.987
USH2A	O75445-1.3	Q379G	Pathogenic	0.769
USH2A	O75445-1.3	Q379H	Pathogenic	0.833
USH2A	O75445-1.3	Q379I	Pathogenic	0.991
USH2A	O75445-1.3	Q379K	Pathogenic	0.609
USH2A	O75445-1.3	Q379L	Pathogenic	0.979
USH2A	O75445-1.3	Q379M	Pathogenic	0.876
USH2A	O75445-1.3	Q379N	Pathogenic	0.763
USH2A	O75445-1.3	Q379P	Pathogenic	0.889
USH2A	O75445-1.3	Q379R	Pathogenic	0.508
USH2A	O75445-1.3	Q379S	Pathogenic	0.583
USH2A	O75445-1.3	Q379T	Pathogenic	0.875
USH2A	O75445-1.3	Q379V	Pathogenic	0.974
USH2A	O75445-1.3	Q379W	Pathogenic	0.946
USH2A	O75445-1.3	Q379Y	Pathogenic	0.891
USH2A	O75445-1.3	Y380A	Pathogenic	0.94
USH2A	O75445-1.3	Y380C	Pathogenic	0.954
USH2A	O75445-1.3	Y380D	Pathogenic	0.992
USH2A	O75445-1.3	Y380E	Pathogenic	0.99
USH2A	O75445-1.3	Y380F	Pathogenic	0.708
USH2A	O75445-1.3	Y380G	Pathogenic	0.957
USH2A	O75445-1.3	Y380H	Pathogenic	0.763
USH2A	O75445-1.3	Y380I	Pathogenic	0.979
USH2A	O75445-1.3	Y380K	Pathogenic	0.996
USH2A	O75445-1.3	Y380L	Pathogenic	0.978
USH2A	O75445-1.3	Y380M	Pathogenic	0.972
USH2A	O75445-1.3	Y380N	Pathogenic	0.984
USH2A	O75445-1.3	Y380P	Pathogenic	0.984
USH2A	O75445-1.3	Y380Q	Pathogenic	0.976
USH2A	O75445-1.3	Y380R	Pathogenic	0.996
USH2A	O75445-1.3	Y380S	Pathogenic	0.957
USH2A	O75445-1.3	Y380T	Pathogenic	0.974
USH2A	O75445-1.3	Y380V	Pathogenic	0.95
USH2A	O75445-1.3	Y380W	Pathogenic	0.807
USH2A	O75445-1.3	Q381A	Pathogenic	0.903
USH2A	O75445-1.3	Q381C	Pathogenic	0.992
USH2A	O75445-1.3	Q381D	Pathogenic	0.9
USH2A	O75445-1.3	Q381E	Pathogenic	0.741
USH2A	O75445-1.3	Q381F	Pathogenic	0.996
USH2A	O75445-1.3	Q381G	Pathogenic	0.909
USH2A	O75445-1.3	Q381H	Pathogenic	0.937
USH2A	O75445-1.3	Q381I	Pathogenic	0.997
USH2A	O75445-1.3	Q381K	Pathogenic	0.823
USH2A	O75445-1.3	Q381L	Pathogenic	0.993
USH2A	O75445-1.3	Q381M	Pathogenic	0.955
USH2A	O75445-1.3	Q381N	Pathogenic	0.906
USH2A	O75445-1.3	Q381P	Pathogenic	0.96
USH2A	O75445-1.3	Q381R	Pathogenic	0.756
USH2A	O75445-1.3	Q381S	Pathogenic	0.807
USH2A	O75445-1.3	Q381T	Pathogenic	0.955
USH2A	O75445-1.3	Q381V	Pathogenic	0.991
USH2A	O75445-1.3	Q381W	Pathogenic	0.981
USH2A	O75445-1.3	Q381Y	Pathogenic	0.961
USH2A	O75445-1.3	V382A	Pathogenic	0.793
USH2A	O75445-1.3	V382C	Pathogenic	0.92
USH2A	O75445-1.3	V382D	Pathogenic	0.994
USH2A	O75445-1.3	V382E	Pathogenic	0.99
USH2A	O75445-1.3	V382F	Pathogenic	0.905
USH2A	O75445-1.3	V382G	Pathogenic	0.966
USH2A	O75445-1.3	V382H	Pathogenic	0.991
USH2A	O75445-1.3	V382I	Neutral	0.335
USH2A	O75445-1.3	V382K	Pathogenic	0.98
USH2A	O75445-1.3	V382L	Pathogenic	0.714
USH2A	O75445-1.3	V382M	Pathogenic	0.664
USH2A	O75445-1.3	V382N	Pathogenic	0.995
USH2A	O75445-1.3	V382P	Pathogenic	0.971
USH2A	O75445-1.3	V382Q	Pathogenic	0.985
USH2A	O75445-1.3	V382R	Pathogenic	0.987
USH2A	O75445-1.3	V382S	Pathogenic	0.966
USH2A	O75445-1.3	V382T	Pathogenic	0.9
USH2A	O75445-1.3	V382W	Pathogenic	0.962
USH2A	O75445-1.3	V382Y	Pathogenic	0.871
USH2A	O75445-1.3	F383A	Pathogenic	0.945
USH2A	O75445-1.3	F383C	Pathogenic	0.957
USH2A	O75445-1.3	F383D	Pathogenic	0.993
USH2A	O75445-1.3	F383E	Pathogenic	0.996
USH2A	O75445-1.3	F383G	Pathogenic	0.961
USH2A	O75445-1.3	F383H	Pathogenic	0.977
USH2A	O75445-1.3	F383I	Pathogenic	0.908
USH2A	O75445-1.3	F383K	Pathogenic	0.998
USH2A	O75445-1.3	F383L	Pathogenic	0.911
USH2A	O75445-1.3	F383M	Pathogenic	0.928
USH2A	O75445-1.3	F383N	Pathogenic	0.994
USH2A	O75445-1.3	F383P	Pathogenic	0.993
USH2A	O75445-1.3	F383Q	Pathogenic	0.996
USH2A	O75445-1.3	F383R	Pathogenic	0.998
USH2A	O75445-1.3	F383S	Pathogenic	0.961
USH2A	O75445-1.3	F383T	Pathogenic	0.976
USH2A	O75445-1.3	F383V	Pathogenic	0.942
USH2A	O75445-1.3	F383W	Pathogenic	0.758
USH2A	O75445-1.3	F383Y	Pathogenic	0.593
USH2A	O75445-1.3	Y384A	Pathogenic	0.715
USH2A	O75445-1.3	Y384C	Pathogenic	0.771
USH2A	O75445-1.3	Y384D	Pathogenic	0.955
USH2A	O75445-1.3	Y384E	Pathogenic	0.939
USH2A	O75445-1.3	Y384F	Neutral	0.281
USH2A	O75445-1.3	Y384G	Pathogenic	0.783
USH2A	O75445-1.3	Y384H	Neutral	0.341
USH2A	O75445-1.3	Y384I	Pathogenic	0.883
USH2A	O75445-1.3	Y384K	Pathogenic	0.977
USH2A	O75445-1.3	Y384L	Pathogenic	0.877
USH2A	O75445-1.3	Y384M	Pathogenic	0.85
USH2A	O75445-1.3	Y384N	Pathogenic	0.909
USH2A	O75445-1.3	Y384P	Pathogenic	0.907
USH2A	O75445-1.3	Y384Q	Pathogenic	0.866
USH2A	O75445-1.3	Y384R	Pathogenic	0.976
USH2A	O75445-1.3	Y384S	Pathogenic	0.783
USH2A	O75445-1.3	Y384T	Pathogenic	0.855
USH2A	O75445-1.3	Y384V	Pathogenic	0.753
USH2A	O75445-1.3	Y384W	Neutral	0.402
USH2A	O75445-1.3	I385A	Pathogenic	0.54
USH2A	O75445-1.3	I385C	Pathogenic	0.607
USH2A	O75445-1.3	I385D	Pathogenic	0.958
USH2A	O75445-1.3	I385E	Pathogenic	0.974
USH2A	O75445-1.3	I385F	Pathogenic	0.519
USH2A	O75445-1.3	I385G	Pathogenic	0.898
USH2A	O75445-1.3	I385H	Pathogenic	0.972
USH2A	O75445-1.3	I385K	Pathogenic	0.981
USH2A	O75445-1.3	I385L	Neutral	0.235
USH2A	O75445-1.3	I385M	Neutral	0.47
USH2A	O75445-1.3	I385N	Pathogenic	0.961
USH2A	O75445-1.3	I385P	Pathogenic	0.913
USH2A	O75445-1.3	I385Q	Pathogenic	0.973
USH2A	O75445-1.3	I385R	Pathogenic	0.971
USH2A	O75445-1.3	I385S	Pathogenic	0.794
USH2A	O75445-1.3	I385T	Pathogenic	0.735
USH2A	O75445-1.3	I385V	Neutral	0.085
USH2A	O75445-1.3	I385W	Pathogenic	0.866
USH2A	O75445-1.3	I385Y	Pathogenic	0.754
USH2A	O75445-1.3	I386A	Pathogenic	0.654
USH2A	O75445-1.3	I386C	Pathogenic	0.713
USH2A	O75445-1.3	I386D	Pathogenic	0.973
USH2A	O75445-1.3	I386E	Pathogenic	0.984
USH2A	O75445-1.3	I386F	Pathogenic	0.635
USH2A	O75445-1.3	I386G	Pathogenic	0.934
USH2A	O75445-1.3	I386H	Pathogenic	0.982
USH2A	O75445-1.3	I386K	Pathogenic	0.988
USH2A	O75445-1.3	I386L	Neutral	0.331
USH2A	O75445-1.3	I386M	Pathogenic	0.588
USH2A	O75445-1.3	I386N	Pathogenic	0.975
USH2A	O75445-1.3	I386P	Pathogenic	0.944
USH2A	O75445-1.3	I386Q	Pathogenic	0.983
USH2A	O75445-1.3	I386R	Pathogenic	0.982
USH2A	O75445-1.3	I386S	Pathogenic	0.861
USH2A	O75445-1.3	I386T	Pathogenic	0.817
USH2A	O75445-1.3	I386V	Neutral	0.13
USH2A	O75445-1.3	I386W	Pathogenic	0.912
USH2A	O75445-1.3	I386Y	Pathogenic	0.831
USH2A	O75445-1.3	I387A	Neutral	0.193
USH2A	O75445-1.3	I387C	Neutral	0.239
USH2A	O75445-1.3	I387D	Pathogenic	0.822
USH2A	O75445-1.3	I387E	Pathogenic	0.885
USH2A	O75445-1.3	I387F	Neutral	0.18
USH2A	O75445-1.3	I387G	Pathogenic	0.643
USH2A	O75445-1.3	I387H	Pathogenic	0.875
USH2A	O75445-1.3	I387K	Pathogenic	0.912
USH2A	O75445-1.3	I387L	Neutral	0.059
USH2A	O75445-1.3	I387M	Neutral	0.153
USH2A	O75445-1.3	I387N	Pathogenic	0.833
USH2A	O75445-1.3	I387P	Pathogenic	0.68
USH2A	O75445-1.3	I387Q	Pathogenic	0.88
USH2A	O75445-1.3	I387R	Pathogenic	0.874
USH2A	O75445-1.3	I387S	Neutral	0.44
USH2A	O75445-1.3	I387T	Neutral	0.361
USH2A	O75445-1.3	I387V	Neutral	0.019
USH2A	O75445-1.3	I387W	Pathogenic	0.569
USH2A	O75445-1.3	I387Y	Neutral	0.385
USH2A	O75445-1.3	Q388A	Pathogenic	0.846
USH2A	O75445-1.3	Q388C	Pathogenic	0.987
USH2A	O75445-1.3	Q388D	Pathogenic	0.84
USH2A	O75445-1.3	Q388E	Pathogenic	0.627
USH2A	O75445-1.3	Q388F	Pathogenic	0.993
USH2A	O75445-1.3	Q388G	Pathogenic	0.854
USH2A	O75445-1.3	Q388H	Pathogenic	0.897
USH2A	O75445-1.3	Q388I	Pathogenic	0.995
USH2A	O75445-1.3	Q388K	Pathogenic	0.732
USH2A	O75445-1.3	Q388L	Pathogenic	0.988
USH2A	O75445-1.3	Q388M	Pathogenic	0.926
USH2A	O75445-1.3	Q388N	Pathogenic	0.85
USH2A	O75445-1.3	Q388P	Pathogenic	0.934
USH2A	O75445-1.3	Q388R	Pathogenic	0.644
USH2A	O75445-1.3	Q388S	Pathogenic	0.71
USH2A	O75445-1.3	Q388T	Pathogenic	0.925
USH2A	O75445-1.3	Q388V	Pathogenic	0.985
USH2A	O75445-1.3	Q388W	Pathogenic	0.969
USH2A	O75445-1.3	Q388Y	Pathogenic	0.935
USH2A	O75445-1.3	F389A	Pathogenic	0.95
USH2A	O75445-1.3	F389C	Pathogenic	0.961
USH2A	O75445-1.3	F389D	Pathogenic	0.994
USH2A	O75445-1.3	F389E	Pathogenic	0.996
USH2A	O75445-1.3	F389G	Pathogenic	0.965
USH2A	O75445-1.3	F389H	Pathogenic	0.979
USH2A	O75445-1.3	F389I	Pathogenic	0.916
USH2A	O75445-1.3	F389K	Pathogenic	0.999
USH2A	O75445-1.3	F389L	Pathogenic	0.919
USH2A	O75445-1.3	F389M	Pathogenic	0.935
USH2A	O75445-1.3	F389N	Pathogenic	0.994
USH2A	O75445-1.3	F389P	Pathogenic	0.994
USH2A	O75445-1.3	F389Q	Pathogenic	0.996
USH2A	O75445-1.3	F389R	Pathogenic	0.998
USH2A	O75445-1.3	F389S	Pathogenic	0.965
USH2A	O75445-1.3	F389T	Pathogenic	0.978
USH2A	O75445-1.3	F389V	Pathogenic	0.947
USH2A	O75445-1.3	F389W	Pathogenic	0.776
USH2A	O75445-1.3	F389Y	Pathogenic	0.617
USH2A	O75445-1.3	F390A	Neutral	0.117
USH2A	O75445-1.3	F390C	Neutral	0.149
USH2A	O75445-1.3	F390D	Pathogenic	0.528
USH2A	O75445-1.3	F390E	Pathogenic	0.652
USH2A	O75445-1.3	F390G	Neutral	0.161
USH2A	O75445-1.3	F390H	Neutral	0.246
USH2A	O75445-1.3	F390I	Neutral	0.071
USH2A	O75445-1.3	F390K	Pathogenic	0.837
USH2A	O75445-1.3	F390L	Neutral	0.074
USH2A	O75445-1.3	F390M	Neutral	0.091
USH2A	O75445-1.3	F390N	Pathogenic	0.547
USH2A	O75445-1.3	F390P	Pathogenic	0.542
USH2A	O75445-1.3	F390Q	Pathogenic	0.641
USH2A	O75445-1.3	F390R	Pathogenic	0.773
USH2A	O75445-1.3	F390S	Neutral	0.16
USH2A	O75445-1.3	F390T	Neutral	0.239
USH2A	O75445-1.3	F390V	Neutral	0.112
USH2A	O75445-1.3	F390W	Neutral	0.024
USH2A	O75445-1.3	F390Y	Neutral	0.011
USH2A	O75445-1.3	S391A	Neutral	0.308
USH2A	O75445-1.3	S391C	Pathogenic	0.722
USH2A	O75445-1.3	S391D	Neutral	0.456
USH2A	O75445-1.3	S391E	Neutral	0.306
USH2A	O75445-1.3	S391F	Pathogenic	0.647
USH2A	O75445-1.3	S391G	Neutral	0.322
USH2A	O75445-1.3	S391H	Neutral	0.378
USH2A	O75445-1.3	S391I	Pathogenic	0.724
USH2A	O75445-1.3	S391K	Neutral	0.186
USH2A	O75445-1.3	S391L	Pathogenic	0.714
USH2A	O75445-1.3	S391M	Neutral	0.464
USH2A	O75445-1.3	S391N	Neutral	0.224
USH2A	O75445-1.3	S391P	Pathogenic	0.667
USH2A	O75445-1.3	S391Q	Neutral	0.234
USH2A	O75445-1.3	S391R	Neutral	0.257
USH2A	O75445-1.3	S391T	Neutral	0.217
USH2A	O75445-1.3	S391V	Pathogenic	0.783
USH2A	O75445-1.3	S391W	Pathogenic	0.682
USH2A	O75445-1.3	S391Y	Pathogenic	0.501
USH2A	O75445-1.3	P392A	Neutral	0.492
USH2A	O75445-1.3	P392C	Pathogenic	0.896
USH2A	O75445-1.3	P392D	Pathogenic	0.77
USH2A	O75445-1.3	P392E	Pathogenic	0.638
USH2A	O75445-1.3	P392F	Pathogenic	0.888
USH2A	O75445-1.3	P392G	Pathogenic	0.583
USH2A	O75445-1.3	P392H	Pathogenic	0.673
USH2A	O75445-1.3	P392I	Pathogenic	0.832
USH2A	O75445-1.3	P392K	Neutral	0.477
USH2A	O75445-1.3	P392L	Pathogenic	0.825
USH2A	O75445-1.3	P392M	Pathogenic	0.621
USH2A	O75445-1.3	P392N	Pathogenic	0.857
USH2A	O75445-1.3	P392Q	Pathogenic	0.549
USH2A	O75445-1.3	P392R	Pathogenic	0.58
USH2A	O75445-1.3	P392S	Pathogenic	0.582
USH2A	O75445-1.3	P392T	Pathogenic	0.654
USH2A	O75445-1.3	P392V	Pathogenic	0.749
USH2A	O75445-1.3	P392W	Pathogenic	0.802
USH2A	O75445-1.3	P392Y	Pathogenic	0.654
USH2A	O75445-1.3	Q393A	Neutral	0.326
USH2A	O75445-1.3	Q393C	Pathogenic	0.866
USH2A	O75445-1.3	Q393D	Neutral	0.316
USH2A	O75445-1.3	Q393E	Neutral	0.129
USH2A	O75445-1.3	Q393F	Pathogenic	0.924
USH2A	O75445-1.3	Q393G	Neutral	0.34
USH2A	O75445-1.3	Q393H	Neutral	0.436
USH2A	O75445-1.3	Q393I	Pathogenic	0.946
USH2A	O75445-1.3	Q393K	Neutral	0.194
USH2A	O75445-1.3	Q393L	Pathogenic	0.879
USH2A	O75445-1.3	Q393M	Pathogenic	0.524
USH2A	O75445-1.3	Q393N	Neutral	0.333
USH2A	O75445-1.3	Q393P	Pathogenic	0.554
USH2A	O75445-1.3	Q393R	Neutral	0.138
USH2A	O75445-1.3	Q393S	Neutral	0.178
USH2A	O75445-1.3	Q393T	Pathogenic	0.521
USH2A	O75445-1.3	Q393V	Pathogenic	0.855
USH2A	O75445-1.3	Q393W	Pathogenic	0.731
USH2A	O75445-1.3	Q393Y	Pathogenic	0.56
USH2A	O75445-1.3	P394A	Pathogenic	0.868
USH2A	O75445-1.3	P394C	Pathogenic	0.983
USH2A	O75445-1.3	P394D	Pathogenic	0.958
USH2A	O75445-1.3	P394E	Pathogenic	0.923
USH2A	O75445-1.3	P394F	Pathogenic	0.982
USH2A	O75445-1.3	P394G	Pathogenic	0.905
USH2A	O75445-1.3	P394H	Pathogenic	0.933
USH2A	O75445-1.3	P394I	Pathogenic	0.971
USH2A	O75445-1.3	P394K	Pathogenic	0.86
USH2A	O75445-1.3	P394L	Pathogenic	0.97
USH2A	O75445-1.3	P394M	Pathogenic	0.917
USH2A	O75445-1.3	P394N	Pathogenic	0.976
USH2A	O75445-1.3	P394Q	Pathogenic	0.892
USH2A	O75445-1.3	P394R	Pathogenic	0.903
USH2A	O75445-1.3	P394S	Pathogenic	0.904
USH2A	O75445-1.3	P394T	Pathogenic	0.927
USH2A	O75445-1.3	P394V	Pathogenic	0.953
USH2A	O75445-1.3	P394W	Pathogenic	0.965
USH2A	O75445-1.3	P394Y	Pathogenic	0.928
USH2A	O75445-1.3	T395A	Neutral	0.103
USH2A	O75445-1.3	T395C	Neutral	0.402
USH2A	O75445-1.3	T395D	Neutral	0.478
USH2A	O75445-1.3	T395E	Neutral	0.354
USH2A	O75445-1.3	T395F	Neutral	0.427
USH2A	O75445-1.3	T395G	Neutral	0.264
USH2A	O75445-1.3	T395H	Neutral	0.39
USH2A	O75445-1.3	T395I	Neutral	0.319
USH2A	O75445-1.3	T395K	Neutral	0.221
USH2A	O75445-1.3	T395L	Neutral	0.308
USH2A	O75445-1.3	T395M	Neutral	0.26
USH2A	O75445-1.3	T395N	Neutral	0.263
USH2A	O75445-1.3	T395P	Neutral	0.401
USH2A	O75445-1.3	T395Q	Neutral	0.275
USH2A	O75445-1.3	T395R	Neutral	0.158
USH2A	O75445-1.3	T395S	Neutral	0.064
USH2A	O75445-1.3	T395V	Neutral	0.22
USH2A	O75445-1.3	T395W	Neutral	0.276
USH2A	O75445-1.3	T395Y	Neutral	0.289
USH2A	O75445-1.3	E396A	Neutral	0.043
USH2A	O75445-1.3	E396C	Pathogenic	0.578
USH2A	O75445-1.3	E396D	Neutral	0.005
USH2A	O75445-1.3	E396F	Neutral	0.449
USH2A	O75445-1.3	E396G	Neutral	0.045
USH2A	O75445-1.3	E396H	Neutral	0.049
USH2A	O75445-1.3	E396I	Pathogenic	0.538
USH2A	O75445-1.3	E396K	Neutral	0.011
USH2A	O75445-1.3	E396L	Pathogenic	0.526
USH2A	O75445-1.3	E396M	Neutral	0.278
USH2A	O75445-1.3	E396N	Neutral	0.031
USH2A	O75445-1.3	E396P	Neutral	0.103
USH2A	O75445-1.3	E396Q	Neutral	0.009
USH2A	O75445-1.3	E396R	Neutral	0.016
USH2A	O75445-1.3	E396S	Neutral	0.02
USH2A	O75445-1.3	E396T	Neutral	0.091
USH2A	O75445-1.3	E396V	Neutral	0.352
USH2A	O75445-1.3	E396W	Neutral	0.294
USH2A	O75445-1.3	E396Y	Neutral	0.163
USH2A	O75445-1.3	I397A	Neutral	0.241
USH2A	O75445-1.3	I397C	Neutral	0.295
USH2A	O75445-1.3	I397D	Pathogenic	0.859
USH2A	O75445-1.3	I397E	Pathogenic	0.911
USH2A	O75445-1.3	I397F	Neutral	0.226
USH2A	O75445-1.3	I397G	Pathogenic	0.705
USH2A	O75445-1.3	I397H	Pathogenic	0.903
USH2A	O75445-1.3	I397K	Pathogenic	0.932
USH2A	O75445-1.3	I397L	Neutral	0.077
USH2A	O75445-1.3	I397M	Neutral	0.194
USH2A	O75445-1.3	I397N	Pathogenic	0.868
USH2A	O75445-1.3	I397P	Pathogenic	0.739
USH2A	O75445-1.3	I397Q	Pathogenic	0.907
USH2A	O75445-1.3	I397R	Pathogenic	0.902
USH2A	O75445-1.3	I397S	Pathogenic	0.51
USH2A	O75445-1.3	I397T	Neutral	0.429
USH2A	O75445-1.3	I397V	Neutral	0.025
USH2A	O75445-1.3	I397W	Pathogenic	0.637
USH2A	O75445-1.3	I397Y	Neutral	0.453
USH2A	O75445-1.3	R398A	Neutral	0.092
USH2A	O75445-1.3	R398C	Pathogenic	0.575
USH2A	O75445-1.3	R398D	Neutral	0.226
USH2A	O75445-1.3	R398E	Neutral	0.096
USH2A	O75445-1.3	R398F	Pathogenic	0.907
USH2A	O75445-1.3	R398G	Neutral	0.097
USH2A	O75445-1.3	R398H	Neutral	0.172
USH2A	O75445-1.3	R398I	Pathogenic	0.873
USH2A	O75445-1.3	R398K	Neutral	0.038
USH2A	O75445-1.3	R398L	Pathogenic	0.742
USH2A	O75445-1.3	R398M	Neutral	0.499
USH2A	O75445-1.3	R398N	Neutral	0.067
USH2A	O75445-1.3	R398P	Neutral	0.372
USH2A	O75445-1.3	R398Q	Neutral	0.063
USH2A	O75445-1.3	R398S	Neutral	0.093
USH2A	O75445-1.3	R398T	Neutral	0.185
USH2A	O75445-1.3	R398V	Pathogenic	0.737
USH2A	O75445-1.3	R398W	Pathogenic	0.92
USH2A	O75445-1.3	R398Y	Pathogenic	0.774
USH2A	O75445-1.3	I399A	Pathogenic	0.888
USH2A	O75445-1.3	I399C	Pathogenic	0.913
USH2A	O75445-1.3	I399D	Pathogenic	0.994
USH2A	O75445-1.3	I399E	Pathogenic	0.996
USH2A	O75445-1.3	I399F	Pathogenic	0.88
USH2A	O75445-1.3	I399G	Pathogenic	0.984
USH2A	O75445-1.3	I399H	Pathogenic	0.996
USH2A	O75445-1.3	I399K	Pathogenic	0.997
USH2A	O75445-1.3	I399L	Pathogenic	0.676
USH2A	O75445-1.3	I399M	Pathogenic	0.857
USH2A	O75445-1.3	I399N	Pathogenic	0.994
USH2A	O75445-1.3	I399P	Pathogenic	0.986
USH2A	O75445-1.3	I399Q	Pathogenic	0.996
USH2A	O75445-1.3	I399R	Pathogenic	0.996
USH2A	O75445-1.3	I399S	Pathogenic	0.963
USH2A	O75445-1.3	I399T	Pathogenic	0.949
USH2A	O75445-1.3	I399V	Neutral	0.387
USH2A	O75445-1.3	I399W	Pathogenic	0.978
USH2A	O75445-1.3	I399Y	Pathogenic	0.954
USH2A	O75445-1.3	Q400A	Pathogenic	0.57
USH2A	O75445-1.3	Q400C	Pathogenic	0.947
USH2A	O75445-1.3	Q400D	Pathogenic	0.559
USH2A	O75445-1.3	Q400E	Neutral	0.288
USH2A	O75445-1.3	Q400F	Pathogenic	0.971
USH2A	O75445-1.3	Q400G	Pathogenic	0.585
USH2A	O75445-1.3	Q400H	Pathogenic	0.679
USH2A	O75445-1.3	Q400I	Pathogenic	0.979
USH2A	O75445-1.3	Q400K	Neutral	0.397
USH2A	O75445-1.3	Q400L	Pathogenic	0.952
USH2A	O75445-1.3	Q400M	Pathogenic	0.751
USH2A	O75445-1.3	Q400N	Pathogenic	0.578
USH2A	O75445-1.3	Q400P	Pathogenic	0.773
USH2A	O75445-1.3	Q400R	Neutral	0.304
USH2A	O75445-1.3	Q400S	Neutral	0.372
USH2A	O75445-1.3	Q400T	Pathogenic	0.748
USH2A	O75445-1.3	Q400V	Pathogenic	0.941
USH2A	O75445-1.3	Q400W	Pathogenic	0.881
USH2A	O75445-1.3	Q400Y	Pathogenic	0.777
USH2A	O75445-1.3	R401A	Pathogenic	0.643
USH2A	O75445-1.3	R401C	Pathogenic	0.96
USH2A	O75445-1.3	R401D	Pathogenic	0.839
USH2A	O75445-1.3	R401E	Pathogenic	0.655
USH2A	O75445-1.3	R401F	Pathogenic	0.994
USH2A	O75445-1.3	R401G	Pathogenic	0.657
USH2A	O75445-1.3	R401H	Pathogenic	0.788
USH2A	O75445-1.3	R401I	Pathogenic	0.992
USH2A	O75445-1.3	R401K	Neutral	0.414
USH2A	O75445-1.3	R401L	Pathogenic	0.981
USH2A	O75445-1.3	R401M	Pathogenic	0.947
USH2A	O75445-1.3	R401N	Pathogenic	0.561
USH2A	O75445-1.3	R401P	Pathogenic	0.914
USH2A	O75445-1.3	R401Q	Pathogenic	0.546
USH2A	O75445-1.3	R401S	Pathogenic	0.648
USH2A	O75445-1.3	R401T	Pathogenic	0.802
USH2A	O75445-1.3	R401V	Pathogenic	0.98
USH2A	O75445-1.3	R401W	Pathogenic	0.995
USH2A	O75445-1.3	R401Y	Pathogenic	0.984
USH2A	O75445-1.3	K402A	Pathogenic	0.533
USH2A	O75445-1.3	K402C	Pathogenic	0.939
USH2A	O75445-1.3	K402D	Pathogenic	0.591
USH2A	O75445-1.3	K402E	Neutral	0.345
USH2A	O75445-1.3	K402F	Pathogenic	0.991
USH2A	O75445-1.3	K402G	Pathogenic	0.548
USH2A	O75445-1.3	K402H	Pathogenic	0.843
USH2A	O75445-1.3	K402I	Pathogenic	0.987
USH2A	O75445-1.3	K402L	Pathogenic	0.97
USH2A	O75445-1.3	K402M	Pathogenic	0.918
USH2A	O75445-1.3	K402N	Neutral	0.447
USH2A	O75445-1.3	K402P	Pathogenic	0.745
USH2A	O75445-1.3	K402Q	Neutral	0.432
USH2A	O75445-1.3	K402R	Neutral	0.229
USH2A	O75445-1.3	K402S	Neutral	0.338
USH2A	O75445-1.3	K402T	Pathogenic	0.719
USH2A	O75445-1.3	K402V	Pathogenic	0.933
USH2A	O75445-1.3	K402W	Pathogenic	0.983
USH2A	O75445-1.3	K402Y	Pathogenic	0.963
USH2A	O75445-1.3	K403A	Pathogenic	0.554
USH2A	O75445-1.3	K403C	Pathogenic	0.943
USH2A	O75445-1.3	K403D	Pathogenic	0.612
USH2A	O75445-1.3	K403E	Neutral	0.365
USH2A	O75445-1.3	K403F	Pathogenic	0.992
USH2A	O75445-1.3	K403G	Pathogenic	0.57
USH2A	O75445-1.3	K403H	Pathogenic	0.854
USH2A	O75445-1.3	K403I	Pathogenic	0.988
USH2A	O75445-1.3	K403L	Pathogenic	0.973
USH2A	O75445-1.3	K403M	Pathogenic	0.925
USH2A	O75445-1.3	K403N	Neutral	0.468
USH2A	O75445-1.3	K403P	Pathogenic	0.762
USH2A	O75445-1.3	K403Q	Neutral	0.454
USH2A	O75445-1.3	K403R	Neutral	0.244
USH2A	O75445-1.3	K403S	Neutral	0.358
USH2A	O75445-1.3	K403T	Pathogenic	0.737
USH2A	O75445-1.3	K403V	Pathogenic	0.938
USH2A	O75445-1.3	K403W	Pathogenic	0.984
USH2A	O75445-1.3	K403Y	Pathogenic	0.966
USH2A	O75445-1.3	E404A	Neutral	0.009
USH2A	O75445-1.3	E404C	Neutral	0.219
USH2A	O75445-1.3	E404D	Neutral	0.001
USH2A	O75445-1.3	E404F	Neutral	0.143
USH2A	O75445-1.3	E404G	Neutral	0.01
USH2A	O75445-1.3	E404H	Neutral	0.011
USH2A	O75445-1.3	E404I	Neutral	0.193
USH2A	O75445-1.3	E404K	Neutral	0.002
USH2A	O75445-1.3	E404L	Neutral	0.185
USH2A	O75445-1.3	E404M	Neutral	0.073
USH2A	O75445-1.3	E404N	Neutral	0.006
USH2A	O75445-1.3	E404P	Neutral	0.023
USH2A	O75445-1.3	E404Q	Neutral	0.002
USH2A	O75445-1.3	E404R	Neutral	0.003
USH2A	O75445-1.3	E404S	Neutral	0.004
USH2A	O75445-1.3	E404T	Neutral	0.02
USH2A	O75445-1.3	E404V	Neutral	0.1
USH2A	O75445-1.3	E404W	Neutral	0.079
USH2A	O75445-1.3	E404Y	Neutral	0.038
USH2A	O75445-1.3	N405A	Neutral	0.186
USH2A	O75445-1.3	N405C	Pathogenic	0.573
USH2A	O75445-1.3	N405D	Neutral	0.028
USH2A	O75445-1.3	N405E	Neutral	0.045
USH2A	O75445-1.3	N405F	Neutral	0.441
USH2A	O75445-1.3	N405G	Neutral	0.02
USH2A	O75445-1.3	N405H	Neutral	0.022
USH2A	O75445-1.3	N405I	Pathogenic	0.531
USH2A	O75445-1.3	N405K	Neutral	0.024
USH2A	O75445-1.3	N405L	Pathogenic	0.518
USH2A	O75445-1.3	N405M	Neutral	0.272
USH2A	O75445-1.3	N405P	Neutral	0.37
USH2A	O75445-1.3	N405Q	Neutral	0.046
USH2A	O75445-1.3	N405R	Neutral	0.016
USH2A	O75445-1.3	N405S	Neutral	0.019
USH2A	O75445-1.3	N405T	Neutral	0.09
USH2A	O75445-1.3	N405V	Pathogenic	0.609
USH2A	O75445-1.3	N405W	Neutral	0.48
USH2A	O75445-1.3	N405Y	Neutral	0.159
USH2A	O75445-1.3	S406A	Neutral	0.013
USH2A	O75445-1.3	S406C	Neutral	0.069
USH2A	O75445-1.3	S406D	Neutral	0.024
USH2A	O75445-1.3	S406E	Neutral	0.013
USH2A	O75445-1.3	S406F	Neutral	0.05
USH2A	O75445-1.3	S406G	Neutral	0.013
USH2A	O75445-1.3	S406H	Neutral	0.017
USH2A	O75445-1.3	S406I	Neutral	0.07
USH2A	O75445-1.3	S406K	Neutral	0.007
USH2A	O75445-1.3	S406L	Neutral	0.067
USH2A	O75445-1.3	S406M	Neutral	0.024
USH2A	O75445-1.3	S406N	Neutral	0.008
USH2A	O75445-1.3	S406P	Neutral	0.054
USH2A	O75445-1.3	S406Q	Neutral	0.009
USH2A	O75445-1.3	S406R	Neutral	0.01
USH2A	O75445-1.3	S406T	Neutral	0.008
USH2A	O75445-1.3	S406V	Neutral	0.094
USH2A	O75445-1.3	S406W	Neutral	0.058
USH2A	O75445-1.3	S406Y	Neutral	0.028
USH2A	O75445-1.3	L407A	Neutral	0.077
USH2A	O75445-1.3	L407C	Neutral	0.099
USH2A	O75445-1.3	L407D	Pathogenic	0.785
USH2A	O75445-1.3	L407E	Pathogenic	0.727
USH2A	O75445-1.3	L407F	Neutral	0.077
USH2A	O75445-1.3	L407G	Neutral	0.385
USH2A	O75445-1.3	L407H	Pathogenic	0.709
USH2A	O75445-1.3	L407I	Neutral	0.022
USH2A	O75445-1.3	L407K	Pathogenic	0.613
USH2A	O75445-1.3	L407M	Neutral	0.027
USH2A	O75445-1.3	L407N	Pathogenic	0.633
USH2A	O75445-1.3	L407P	Neutral	0.425
USH2A	O75445-1.3	L407Q	Pathogenic	0.527
USH2A	O75445-1.3	L407R	Pathogenic	0.512
USH2A	O75445-1.3	L407S	Neutral	0.214
USH2A	O75445-1.3	L407T	Neutral	0.164
USH2A	O75445-1.3	L407V	Neutral	0.033
USH2A	O75445-1.3	L407W	Neutral	0.182
USH2A	O75445-1.3	L407Y	Neutral	0.178
USH2A	O75445-1.3	D408A	Neutral	0.118
USH2A	O75445-1.3	D408C	Neutral	0.441
USH2A	O75445-1.3	D408E	Neutral	0.004
USH2A	O75445-1.3	D408F	Neutral	0.252
USH2A	O75445-1.3	D408G	Neutral	0.027
USH2A	O75445-1.3	D408H	Neutral	0.047
USH2A	O75445-1.3	D408I	Neutral	0.325
USH2A	O75445-1.3	D408K	Neutral	0.02
USH2A	O75445-1.3	D408L	Pathogenic	0.511
USH2A	O75445-1.3	D408M	Neutral	0.266
USH2A	O75445-1.3	D408N	Neutral	0.013
USH2A	O75445-1.3	D408P	Neutral	0.131
USH2A	O75445-1.3	D408Q	Neutral	0.02
USH2A	O75445-1.3	D408R	Neutral	0.03
USH2A	O75445-1.3	D408S	Neutral	0.026
USH2A	O75445-1.3	D408T	Neutral	0.104
USH2A	O75445-1.3	D408V	Neutral	0.399
USH2A	O75445-1.3	D408W	Neutral	0.282
USH2A	O75445-1.3	D408Y	Neutral	0.155
USH2A	O75445-1.3	W409A	Pathogenic	0.99
USH2A	O75445-1.3	W409C	Pathogenic	0.984
USH2A	O75445-1.3	W409D	Pathogenic	0.999
USH2A	O75445-1.3	W409E	Pathogenic	0.998
USH2A	O75445-1.3	W409F	Pathogenic	0.942
USH2A	O75445-1.3	W409G	Pathogenic	0.966
USH2A	O75445-1.3	W409H	Pathogenic	0.996
USH2A	O75445-1.3	W409I	Pathogenic	0.997
USH2A	O75445-1.3	W409K	Pathogenic	0.999
USH2A	O75445-1.3	W409L	Pathogenic	0.993
USH2A	O75445-1.3	W409M	Pathogenic	0.987
USH2A	O75445-1.3	W409N	Pathogenic	0.999
USH2A	O75445-1.3	W409P	Pathogenic	0.998
USH2A	O75445-1.3	W409Q	Pathogenic	0.996
USH2A	O75445-1.3	W409R	Pathogenic	1.0
USH2A	O75445-1.3	W409S	Pathogenic	0.993
USH2A	O75445-1.3	W409T	Pathogenic	0.991
USH2A	O75445-1.3	W409V	Pathogenic	0.996
USH2A	O75445-1.3	W409Y	Pathogenic	0.929
USH2A	O75445-1.3	E410A	Neutral	0.333
USH2A	O75445-1.3	E410C	Pathogenic	0.939
USH2A	O75445-1.3	E410D	Neutral	0.057
USH2A	O75445-1.3	E410F	Pathogenic	0.901
USH2A	O75445-1.3	E410G	Neutral	0.347
USH2A	O75445-1.3	E410H	Neutral	0.366
USH2A	O75445-1.3	E410I	Pathogenic	0.929
USH2A	O75445-1.3	E410K	Neutral	0.106
USH2A	O75445-1.3	E410L	Pathogenic	0.925
USH2A	O75445-1.3	E410M	Pathogenic	0.811
USH2A	O75445-1.3	E410N	Neutral	0.261
USH2A	O75445-1.3	E410P	Pathogenic	0.562
USH2A	O75445-1.3	E410Q	Neutral	0.096
USH2A	O75445-1.3	E410R	Neutral	0.153
USH2A	O75445-1.3	E410S	Neutral	0.183
USH2A	O75445-1.3	E410T	Pathogenic	0.529
USH2A	O75445-1.3	E410V	Pathogenic	0.859
USH2A	O75445-1.3	E410W	Pathogenic	0.823
USH2A	O75445-1.3	E410Y	Pathogenic	0.685
USH2A	O75445-1.3	D411A	Pathogenic	0.983
USH2A	O75445-1.3	D411C	Pathogenic	0.997
USH2A	O75445-1.3	D411E	Pathogenic	0.621
USH2A	O75445-1.3	D411F	Pathogenic	0.993
USH2A	O75445-1.3	D411G	Pathogenic	0.923
USH2A	O75445-1.3	D411H	Pathogenic	0.955
USH2A	O75445-1.3	D411I	Pathogenic	0.995
USH2A	O75445-1.3	D411K	Pathogenic	0.898
USH2A	O75445-1.3	D411L	Pathogenic	0.998
USH2A	O75445-1.3	D411M	Pathogenic	0.994
USH2A	O75445-1.3	D411N	Pathogenic	0.852
USH2A	O75445-1.3	D411P	Pathogenic	0.985
USH2A	O75445-1.3	D411Q	Pathogenic	0.899
USH2A	O75445-1.3	D411R	Pathogenic	0.93
USH2A	O75445-1.3	D411S	Pathogenic	0.92
USH2A	O75445-1.3	D411T	Pathogenic	0.981
USH2A	O75445-1.3	D411V	Pathogenic	0.997
USH2A	O75445-1.3	D411W	Pathogenic	0.994
USH2A	O75445-1.3	D411Y	Pathogenic	0.988
USH2A	O75445-1.3	W412A	Pathogenic	0.989
USH2A	O75445-1.3	W412C	Pathogenic	0.982
USH2A	O75445-1.3	W412D	Pathogenic	0.999
USH2A	O75445-1.3	W412E	Pathogenic	0.998
USH2A	O75445-1.3	W412F	Pathogenic	0.936
USH2A	O75445-1.3	W412G	Pathogenic	0.963
USH2A	O75445-1.3	W412H	Pathogenic	0.996
USH2A	O75445-1.3	W412I	Pathogenic	0.996
USH2A	O75445-1.3	W412K	Pathogenic	0.999
USH2A	O75445-1.3	W412L	Pathogenic	0.992
USH2A	O75445-1.3	W412M	Pathogenic	0.986
USH2A	O75445-1.3	W412N	Pathogenic	0.999
USH2A	O75445-1.3	W412P	Pathogenic	0.997
USH2A	O75445-1.3	W412Q	Pathogenic	0.996
USH2A	O75445-1.3	W412R	Pathogenic	1.0
USH2A	O75445-1.3	W412S	Pathogenic	0.993
USH2A	O75445-1.3	W412T	Pathogenic	0.99
USH2A	O75445-1.3	W412V	Pathogenic	0.995
USH2A	O75445-1.3	W412Y	Pathogenic	0.921
USH2A	O75445-1.3	Q413A	Pathogenic	0.927
USH2A	O75445-1.3	Q413C	Pathogenic	0.994
USH2A	O75445-1.3	Q413D	Pathogenic	0.924
USH2A	O75445-1.3	Q413E	Pathogenic	0.794
USH2A	O75445-1.3	Q413F	Pathogenic	0.997
USH2A	O75445-1.3	Q413G	Pathogenic	0.931
USH2A	O75445-1.3	Q413H	Pathogenic	0.953
USH2A	O75445-1.3	Q413I	Pathogenic	0.998
USH2A	O75445-1.3	Q413K	Pathogenic	0.863
USH2A	O75445-1.3	Q413L	Pathogenic	0.995
USH2A	O75445-1.3	Q413M	Pathogenic	0.966
USH2A	O75445-1.3	Q413N	Pathogenic	0.929
USH2A	O75445-1.3	Q413P	Pathogenic	0.97
USH2A	O75445-1.3	Q413R	Pathogenic	0.807
USH2A	O75445-1.3	Q413S	Pathogenic	0.85
USH2A	O75445-1.3	Q413T	Pathogenic	0.966
USH2A	O75445-1.3	Q413V	Pathogenic	0.994
USH2A	O75445-1.3	Q413W	Pathogenic	0.986
USH2A	O75445-1.3	Q413Y	Pathogenic	0.971
USH2A	O75445-1.3	Y414A	Pathogenic	0.787
USH2A	O75445-1.3	Y414C	Pathogenic	0.833
USH2A	O75445-1.3	Y414D	Pathogenic	0.969
USH2A	O75445-1.3	Y414E	Pathogenic	0.958
USH2A	O75445-1.3	Y414F	Neutral	0.366
USH2A	O75445-1.3	Y414G	Pathogenic	0.842
USH2A	O75445-1.3	Y414H	Neutral	0.433
USH2A	O75445-1.3	Y414I	Pathogenic	0.917
USH2A	O75445-1.3	Y414K	Pathogenic	0.984
USH2A	O75445-1.3	Y414L	Pathogenic	0.913
USH2A	O75445-1.3	Y414M	Pathogenic	0.893
USH2A	O75445-1.3	Y414N	Pathogenic	0.936
USH2A	O75445-1.3	Y414P	Pathogenic	0.935
USH2A	O75445-1.3	Y414Q	Pathogenic	0.905
USH2A	O75445-1.3	Y414R	Pathogenic	0.984
USH2A	O75445-1.3	Y414S	Pathogenic	0.842
USH2A	O75445-1.3	Y414T	Pathogenic	0.897
USH2A	O75445-1.3	Y414V	Pathogenic	0.818
USH2A	O75445-1.3	Y414W	Neutral	0.498
USH2A	O75445-1.3	F415A	Pathogenic	0.574
USH2A	O75445-1.3	F415C	Pathogenic	0.64
USH2A	O75445-1.3	F415D	Pathogenic	0.919
USH2A	O75445-1.3	F415E	Pathogenic	0.95
USH2A	O75445-1.3	F415G	Pathogenic	0.661
USH2A	O75445-1.3	F415H	Pathogenic	0.768
USH2A	O75445-1.3	F415I	Neutral	0.438
USH2A	O75445-1.3	F415K	Pathogenic	0.981
USH2A	O75445-1.3	F415L	Neutral	0.447
USH2A	O75445-1.3	F415M	Pathogenic	0.505
USH2A	O75445-1.3	F415N	Pathogenic	0.925
USH2A	O75445-1.3	F415P	Pathogenic	0.923
USH2A	O75445-1.3	F415Q	Pathogenic	0.948
USH2A	O75445-1.3	F415R	Pathogenic	0.972
USH2A	O75445-1.3	F415S	Pathogenic	0.66
USH2A	O75445-1.3	F415T	Pathogenic	0.761
USH2A	O75445-1.3	F415V	Pathogenic	0.56
USH2A	O75445-1.3	F415W	Neutral	0.198
USH2A	O75445-1.3	F415Y	Neutral	0.103
USH2A	O75445-1.3	A416C	Pathogenic	0.896
USH2A	O75445-1.3	A416D	Pathogenic	0.979
USH2A	O75445-1.3	A416E	Pathogenic	0.915
USH2A	O75445-1.3	A416F	Pathogenic	0.933
USH2A	O75445-1.3	A416G	Pathogenic	0.878
USH2A	O75445-1.3	A416H	Pathogenic	0.926
USH2A	O75445-1.3	A416I	Pathogenic	0.897
USH2A	O75445-1.3	A416K	Pathogenic	0.847
USH2A	O75445-1.3	A416L	Pathogenic	0.892
USH2A	O75445-1.3	A416M	Pathogenic	0.868
USH2A	O75445-1.3	A416N	Pathogenic	0.973
USH2A	O75445-1.3	A416P	Pathogenic	0.938
USH2A	O75445-1.3	A416Q	Pathogenic	0.881
USH2A	O75445-1.3	A416R	Pathogenic	0.786
USH2A	O75445-1.3	A416S	Pathogenic	0.829
USH2A	O75445-1.3	A416T	Pathogenic	0.834
USH2A	O75445-1.3	A416V	Pathogenic	0.84
USH2A	O75445-1.3	A416W	Pathogenic	0.942
USH2A	O75445-1.3	A416Y	Pathogenic	0.883
USH2A	O75445-1.3	R417A	Neutral	0.197
USH2A	O75445-1.3	R417C	Pathogenic	0.767
USH2A	O75445-1.3	R417D	Neutral	0.415
USH2A	O75445-1.3	R417E	Neutral	0.206
USH2A	O75445-1.3	R417F	Pathogenic	0.96
USH2A	O75445-1.3	R417G	Neutral	0.207
USH2A	O75445-1.3	R417H	Neutral	0.336
USH2A	O75445-1.3	R417I	Pathogenic	0.944
USH2A	O75445-1.3	R417K	Neutral	0.088
USH2A	O75445-1.3	R417L	Pathogenic	0.875
USH2A	O75445-1.3	R417M	Pathogenic	0.708
USH2A	O75445-1.3	R417N	Neutral	0.148
USH2A	O75445-1.3	R417P	Pathogenic	0.59
USH2A	O75445-1.3	R417Q	Neutral	0.141
USH2A	O75445-1.3	R417S	Neutral	0.2
USH2A	O75445-1.3	R417T	Neutral	0.355
USH2A	O75445-1.3	R417V	Pathogenic	0.872
USH2A	O75445-1.3	R417W	Pathogenic	0.965
USH2A	O75445-1.3	R417Y	Pathogenic	0.893
USH2A	O75445-1.3	N418A	Pathogenic	0.933
USH2A	O75445-1.3	N418C	Pathogenic	0.988
USH2A	O75445-1.3	N418D	Pathogenic	0.637
USH2A	O75445-1.3	N418E	Pathogenic	0.744
USH2A	O75445-1.3	N418F	Pathogenic	0.98
USH2A	O75445-1.3	N418G	Pathogenic	0.555
USH2A	O75445-1.3	N418H	Pathogenic	0.574
USH2A	O75445-1.3	N418I	Pathogenic	0.986
USH2A	O75445-1.3	N418K	Pathogenic	0.6
USH2A	O75445-1.3	N418L	Pathogenic	0.985
USH2A	O75445-1.3	N418M	Pathogenic	0.958
USH2A	O75445-1.3	N418P	Pathogenic	0.973
USH2A	O75445-1.3	N418Q	Pathogenic	0.746
USH2A	O75445-1.3	N418R	Neutral	0.499
USH2A	O75445-1.3	N418S	Pathogenic	0.545
USH2A	O75445-1.3	N418T	Pathogenic	0.857
USH2A	O75445-1.3	N418V	Pathogenic	0.99
USH2A	O75445-1.3	N418W	Pathogenic	0.983
USH2A	O75445-1.3	N418Y	Pathogenic	0.92
USH2A	O75445-1.3	C419A	Pathogenic	0.943
USH2A	O75445-1.3	C419D	Pathogenic	0.998
USH2A	O75445-1.3	C419E	Pathogenic	0.998
USH2A	O75445-1.3	C419F	Pathogenic	0.972
USH2A	O75445-1.3	C419G	Pathogenic	0.992
USH2A	O75445-1.3	C419H	Pathogenic	0.993
USH2A	O75445-1.3	C419I	Pathogenic	0.956
USH2A	O75445-1.3	C419K	Pathogenic	0.993
USH2A	O75445-1.3	C419L	Pathogenic	0.954
USH2A	O75445-1.3	C419M	Pathogenic	0.943
USH2A	O75445-1.3	C419N	Pathogenic	0.998
USH2A	O75445-1.3	C419P	Pathogenic	0.996
USH2A	O75445-1.3	C419Q	Pathogenic	0.995
USH2A	O75445-1.3	C419R	Pathogenic	0.99
USH2A	O75445-1.3	C419S	Pathogenic	0.982
USH2A	O75445-1.3	C419T	Pathogenic	0.983
USH2A	O75445-1.3	C419V	Pathogenic	0.968
USH2A	O75445-1.3	C419W	Pathogenic	0.947
USH2A	O75445-1.3	C419Y	Pathogenic	0.951
USH2A	O75445-1.3	G420A	Neutral	0.05
USH2A	O75445-1.3	G420C	Neutral	0.321
USH2A	O75445-1.3	G420D	Neutral	0.065
USH2A	O75445-1.3	G420E	Neutral	0.077
USH2A	O75445-1.3	G420F	Neutral	0.128
USH2A	O75445-1.3	G420H	Neutral	0.046
USH2A	O75445-1.3	G420I	Neutral	0.324
USH2A	O75445-1.3	G420K	Neutral	0.041
USH2A	O75445-1.3	G420L	Neutral	0.313
USH2A	O75445-1.3	G420M	Neutral	0.136
USH2A	O75445-1.3	G420N	Neutral	0.023
USH2A	O75445-1.3	G420P	Neutral	0.138
USH2A	O75445-1.3	G420Q	Neutral	0.055
USH2A	O75445-1.3	G420R	Neutral	0.028
USH2A	O75445-1.3	G420S	Neutral	0.036
USH2A	O75445-1.3	G420T	Neutral	0.103
USH2A	O75445-1.3	G420V	Neutral	0.224
USH2A	O75445-1.3	G420W	Neutral	0.032
USH2A	O75445-1.3	G420Y	Neutral	0.074
USH2A	O75445-1.3	A421C	Neutral	0.009
USH2A	O75445-1.3	A421D	Neutral	0.048
USH2A	O75445-1.3	A421E	Neutral	0.012
USH2A	O75445-1.3	A421F	Neutral	0.015
USH2A	O75445-1.3	A421G	Neutral	0.008
USH2A	O75445-1.3	A421H	Neutral	0.013
USH2A	O75445-1.3	A421I	Neutral	0.009
USH2A	O75445-1.3	A421K	Neutral	0.006
USH2A	O75445-1.3	A421L	Neutral	0.009
USH2A	O75445-1.3	A421M	Neutral	0.007
USH2A	O75445-1.3	A421N	Neutral	0.038
USH2A	O75445-1.3	A421P	Neutral	0.016
USH2A	O75445-1.3	A421Q	Neutral	0.008
USH2A	O75445-1.3	A421R	Neutral	0.004
USH2A	O75445-1.3	A421S	Neutral	0.005
USH2A	O75445-1.3	A421T	Neutral	0.005
USH2A	O75445-1.3	A421V	Neutral	0.006
USH2A	O75445-1.3	A421W	Neutral	0.017
USH2A	O75445-1.3	A421Y	Neutral	0.008
USH2A	O75445-1.3	F422A	Pathogenic	0.894
USH2A	O75445-1.3	F422C	Pathogenic	0.918
USH2A	O75445-1.3	F422D	Pathogenic	0.986
USH2A	O75445-1.3	F422E	Pathogenic	0.992
USH2A	O75445-1.3	F422G	Pathogenic	0.924
USH2A	O75445-1.3	F422H	Pathogenic	0.954
USH2A	O75445-1.3	F422I	Pathogenic	0.83
USH2A	O75445-1.3	F422K	Pathogenic	0.997
USH2A	O75445-1.3	F422L	Pathogenic	0.835
USH2A	O75445-1.3	F422M	Pathogenic	0.865
USH2A	O75445-1.3	F422N	Pathogenic	0.987
USH2A	O75445-1.3	F422P	Pathogenic	0.987
USH2A	O75445-1.3	F422Q	Pathogenic	0.991
USH2A	O75445-1.3	F422R	Pathogenic	0.995
USH2A	O75445-1.3	F422S	Pathogenic	0.924
USH2A	O75445-1.3	F422T	Pathogenic	0.952
USH2A	O75445-1.3	F422V	Pathogenic	0.889
USH2A	O75445-1.3	F422W	Pathogenic	0.607
USH2A	O75445-1.3	F422Y	Neutral	0.419
USH2A	O75445-1.3	G423A	Neutral	0.323
USH2A	O75445-1.3	G423C	Pathogenic	0.812
USH2A	O75445-1.3	G423D	Neutral	0.388
USH2A	O75445-1.3	G423E	Neutral	0.432
USH2A	O75445-1.3	G423F	Pathogenic	0.572
USH2A	O75445-1.3	G423H	Neutral	0.307
USH2A	O75445-1.3	G423I	Pathogenic	0.814
USH2A	O75445-1.3	G423K	Neutral	0.282
USH2A	O75445-1.3	G423L	Pathogenic	0.806
USH2A	O75445-1.3	G423M	Pathogenic	0.591
USH2A	O75445-1.3	G423N	Neutral	0.179
USH2A	O75445-1.3	G423P	Pathogenic	0.593
USH2A	O75445-1.3	G423Q	Neutral	0.345
USH2A	O75445-1.3	G423R	Neutral	0.207
USH2A	O75445-1.3	G423S	Neutral	0.256
USH2A	O75445-1.3	G423T	Pathogenic	0.513
USH2A	O75445-1.3	G423V	Pathogenic	0.725
USH2A	O75445-1.3	G423W	Neutral	0.23
USH2A	O75445-1.3	G423Y	Neutral	0.422
USH2A	O75445-1.3	M424A	Pathogenic	0.914
USH2A	O75445-1.3	M424C	Pathogenic	0.934
USH2A	O75445-1.3	M424D	Pathogenic	0.995
USH2A	O75445-1.3	M424E	Pathogenic	0.993
USH2A	O75445-1.3	M424F	Pathogenic	0.945
USH2A	O75445-1.3	M424G	Pathogenic	0.972
USH2A	O75445-1.3	M424H	Pathogenic	0.993
USH2A	O75445-1.3	M424I	Pathogenic	0.915
USH2A	O75445-1.3	M424K	Pathogenic	0.989
USH2A	O75445-1.3	M424L	Pathogenic	0.817
USH2A	O75445-1.3	M424N	Pathogenic	0.99
USH2A	O75445-1.3	M424P	Pathogenic	0.977
USH2A	O75445-1.3	M424Q	Pathogenic	0.965
USH2A	O75445-1.3	M424R	Pathogenic	0.983
USH2A	O75445-1.3	M424S	Pathogenic	0.939
USH2A	O75445-1.3	M424T	Pathogenic	0.962
USH2A	O75445-1.3	M424V	Pathogenic	0.815
USH2A	O75445-1.3	M424W	Pathogenic	0.952
USH2A	O75445-1.3	M424Y	Pathogenic	0.965
USH2A	O75445-1.3	K425A	Neutral	0.026
USH2A	O75445-1.3	K425C	Neutral	0.263
USH2A	O75445-1.3	K425D	Neutral	0.033
USH2A	O75445-1.3	K425E	Neutral	0.012
USH2A	O75445-1.3	K425F	Pathogenic	0.72
USH2A	O75445-1.3	K425G	Neutral	0.028
USH2A	O75445-1.3	K425H	Neutral	0.111
USH2A	O75445-1.3	K425I	Pathogenic	0.645
USH2A	O75445-1.3	K425L	Neutral	0.431
USH2A	O75445-1.3	K425M	Neutral	0.208
USH2A	O75445-1.3	K425N	Neutral	0.018
USH2A	O75445-1.3	K425P	Neutral	0.064
USH2A	O75445-1.3	K425Q	Neutral	0.017
USH2A	O75445-1.3	K425R	Neutral	0.007
USH2A	O75445-1.3	K425S	Neutral	0.012
USH2A	O75445-1.3	K425T	Neutral	0.056
USH2A	O75445-1.3	K425V	Neutral	0.244
USH2A	O75445-1.3	K425W	Pathogenic	0.568
USH2A	O75445-1.3	K425Y	Neutral	0.381
USH2A	O75445-1.3	N426A	Pathogenic	0.897
USH2A	O75445-1.3	N426C	Pathogenic	0.981
USH2A	O75445-1.3	N426D	Pathogenic	0.523
USH2A	O75445-1.3	N426E	Pathogenic	0.644
USH2A	O75445-1.3	N426F	Pathogenic	0.968
USH2A	O75445-1.3	N426G	Neutral	0.438
USH2A	O75445-1.3	N426H	Neutral	0.457
USH2A	O75445-1.3	N426I	Pathogenic	0.977
USH2A	O75445-1.3	N426K	Neutral	0.484
USH2A	O75445-1.3	N426L	Pathogenic	0.976
USH2A	O75445-1.3	N426M	Pathogenic	0.934
USH2A	O75445-1.3	N426P	Pathogenic	0.957
USH2A	O75445-1.3	N426Q	Pathogenic	0.647
USH2A	O75445-1.3	N426R	Neutral	0.383
USH2A	O75445-1.3	N426S	Neutral	0.428
USH2A	O75445-1.3	N426T	Pathogenic	0.79
USH2A	O75445-1.3	N426V	Pathogenic	0.983
USH2A	O75445-1.3	N426W	Pathogenic	0.972
USH2A	O75445-1.3	N426Y	Pathogenic	0.878
USH2A	O75445-1.3	N427A	Pathogenic	0.983
USH2A	O75445-1.3	N427C	Pathogenic	0.997
USH2A	O75445-1.3	N427D	Pathogenic	0.876
USH2A	O75445-1.3	N427E	Pathogenic	0.921
USH2A	O75445-1.3	N427F	Pathogenic	0.995
USH2A	O75445-1.3	N427G	Pathogenic	0.835
USH2A	O75445-1.3	N427H	Pathogenic	0.845
USH2A	O75445-1.3	N427I	Pathogenic	0.996
USH2A	O75445-1.3	N427K	Pathogenic	0.858
USH2A	O75445-1.3	N427L	Pathogenic	0.996
USH2A	O75445-1.3	N427M	Pathogenic	0.989
USH2A	O75445-1.3	N427P	Pathogenic	0.993
USH2A	O75445-1.3	N427Q	Pathogenic	0.922
USH2A	O75445-1.3	N427R	Pathogenic	0.801
USH2A	O75445-1.3	N427S	Pathogenic	0.829
USH2A	O75445-1.3	N427T	Pathogenic	0.96
USH2A	O75445-1.3	N427V	Pathogenic	0.997
USH2A	O75445-1.3	N427W	Pathogenic	0.996
USH2A	O75445-1.3	N427Y	Pathogenic	0.979
USH2A	O75445-1.3	G428A	Pathogenic	0.812
USH2A	O75445-1.3	G428C	Pathogenic	0.975
USH2A	O75445-1.3	G428D	Pathogenic	0.852
USH2A	O75445-1.3	G428E	Pathogenic	0.874
USH2A	O75445-1.3	G428F	Pathogenic	0.924
USH2A	O75445-1.3	G428H	Pathogenic	0.801
USH2A	O75445-1.3	G428I	Pathogenic	0.975
USH2A	O75445-1.3	G428K	Pathogenic	0.781
USH2A	O75445-1.3	G428L	Pathogenic	0.974
USH2A	O75445-1.3	G428M	Pathogenic	0.929
USH2A	O75445-1.3	G428N	Pathogenic	0.664
USH2A	O75445-1.3	G428P	Pathogenic	0.93
USH2A	O75445-1.3	G428Q	Pathogenic	0.827
USH2A	O75445-1.3	G428R	Pathogenic	0.703
USH2A	O75445-1.3	G428S	Pathogenic	0.757
USH2A	O75445-1.3	G428T	Pathogenic	0.905
USH2A	O75445-1.3	G428V	Pathogenic	0.96
USH2A	O75445-1.3	G428W	Pathogenic	0.731
USH2A	O75445-1.3	G428Y	Pathogenic	0.869
USH2A	O75445-1.3	D429A	Neutral	0.089
USH2A	O75445-1.3	D429C	Neutral	0.365
USH2A	O75445-1.3	D429E	Neutral	0.003
USH2A	O75445-1.3	D429F	Neutral	0.197
USH2A	O75445-1.3	D429G	Neutral	0.02
USH2A	O75445-1.3	D429H	Neutral	0.034
USH2A	O75445-1.3	D429I	Neutral	0.26
USH2A	O75445-1.3	D429K	Neutral	0.014
USH2A	O75445-1.3	D429L	Neutral	0.433
USH2A	O75445-1.3	D429M	Neutral	0.209
USH2A	O75445-1.3	D429N	Neutral	0.01
USH2A	O75445-1.3	D429P	Neutral	0.099
USH2A	O75445-1.3	D429Q	Neutral	0.015
USH2A	O75445-1.3	D429R	Neutral	0.022
USH2A	O75445-1.3	D429S	Neutral	0.019
USH2A	O75445-1.3	D429T	Neutral	0.078
USH2A	O75445-1.3	D429V	Neutral	0.326
USH2A	O75445-1.3	D429W	Neutral	0.223
USH2A	O75445-1.3	D429Y	Neutral	0.118
USH2A	O75445-1.3	L430A	Pathogenic	0.874
USH2A	O75445-1.3	L430C	Pathogenic	0.901
USH2A	O75445-1.3	L430D	Pathogenic	0.997
USH2A	O75445-1.3	L430E	Pathogenic	0.996
USH2A	O75445-1.3	L430F	Pathogenic	0.874
USH2A	O75445-1.3	L430G	Pathogenic	0.981
USH2A	O75445-1.3	L430H	Pathogenic	0.995
USH2A	O75445-1.3	L430I	Pathogenic	0.657
USH2A	O75445-1.3	L430K	Pathogenic	0.992
USH2A	O75445-1.3	L430M	Pathogenic	0.697
USH2A	O75445-1.3	L430N	Pathogenic	0.993
USH2A	O75445-1.3	L430P	Pathogenic	0.984
USH2A	O75445-1.3	L430Q	Pathogenic	0.989
USH2A	O75445-1.3	L430R	Pathogenic	0.989
USH2A	O75445-1.3	L430S	Pathogenic	0.958
USH2A	O75445-1.3	L430T	Pathogenic	0.943
USH2A	O75445-1.3	L430V	Pathogenic	0.742
USH2A	O75445-1.3	L430W	Pathogenic	0.949
USH2A	O75445-1.3	L430Y	Pathogenic	0.948
USH2A	O75445-1.3	E431A	Neutral	0.225
USH2A	O75445-1.3	E431C	Pathogenic	0.899
USH2A	O75445-1.3	E431D	Neutral	0.034
USH2A	O75445-1.3	E431F	Pathogenic	0.841
USH2A	O75445-1.3	E431G	Neutral	0.236
USH2A	O75445-1.3	E431H	Neutral	0.252
USH2A	O75445-1.3	E431I	Pathogenic	0.884
USH2A	O75445-1.3	E431K	Neutral	0.065
USH2A	O75445-1.3	E431L	Pathogenic	0.878
USH2A	O75445-1.3	E431M	Pathogenic	0.714
USH2A	O75445-1.3	E431N	Neutral	0.171
USH2A	O75445-1.3	E431P	Neutral	0.428
USH2A	O75445-1.3	E431Q	Neutral	0.058
USH2A	O75445-1.3	E431R	Neutral	0.095
USH2A	O75445-1.3	E431S	Neutral	0.115
USH2A	O75445-1.3	E431T	Neutral	0.395
USH2A	O75445-1.3	E431V	Pathogenic	0.78
USH2A	O75445-1.3	E431W	Pathogenic	0.73
USH2A	O75445-1.3	E431Y	Pathogenic	0.559
USH2A	O75445-1.3	K432A	Neutral	0.045
USH2A	O75445-1.3	K432C	Neutral	0.387
USH2A	O75445-1.3	K432D	Neutral	0.056
USH2A	O75445-1.3	K432E	Neutral	0.021
USH2A	O75445-1.3	K432F	Pathogenic	0.82
USH2A	O75445-1.3	K432G	Neutral	0.048
USH2A	O75445-1.3	K432H	Neutral	0.181
USH2A	O75445-1.3	K432I	Pathogenic	0.763
USH2A	O75445-1.3	K432L	Pathogenic	0.572
USH2A	O75445-1.3	K432M	Neutral	0.317
USH2A	O75445-1.3	K432N	Neutral	0.032
USH2A	O75445-1.3	K432P	Neutral	0.108
USH2A	O75445-1.3	K432Q	Neutral	0.03
USH2A	O75445-1.3	K432R	Neutral	0.012
USH2A	O75445-1.3	K432S	Neutral	0.021
USH2A	O75445-1.3	K432T	Neutral	0.096
USH2A	O75445-1.3	K432V	Neutral	0.364
USH2A	O75445-1.3	K432W	Pathogenic	0.699
USH2A	O75445-1.3	K432Y	Pathogenic	0.521
USH2A	O75445-1.3	P433A	Pathogenic	0.708
USH2A	O75445-1.3	P433C	Pathogenic	0.956
USH2A	O75445-1.3	P433D	Pathogenic	0.894
USH2A	O75445-1.3	P433E	Pathogenic	0.816
USH2A	O75445-1.3	P433F	Pathogenic	0.952
USH2A	O75445-1.3	P433G	Pathogenic	0.778
USH2A	O75445-1.3	P433H	Pathogenic	0.838
USH2A	O75445-1.3	P433I	Pathogenic	0.926
USH2A	O75445-1.3	P433K	Pathogenic	0.696
USH2A	O75445-1.3	P433L	Pathogenic	0.922
USH2A	O75445-1.3	P433M	Pathogenic	0.804
USH2A	O75445-1.3	P433N	Pathogenic	0.938
USH2A	O75445-1.3	P433Q	Pathogenic	0.754
USH2A	O75445-1.3	P433R	Pathogenic	0.776
USH2A	O75445-1.3	P433S	Pathogenic	0.778
USH2A	O75445-1.3	P433T	Pathogenic	0.826
USH2A	O75445-1.3	P433V	Pathogenic	0.882
USH2A	O75445-1.3	P433W	Pathogenic	0.91
USH2A	O75445-1.3	P433Y	Pathogenic	0.826
USH2A	O75445-1.3	D434A	Pathogenic	0.958
USH2A	O75445-1.3	D434C	Pathogenic	0.993
USH2A	O75445-1.3	D434E	Neutral	0.387
USH2A	O75445-1.3	D434F	Pathogenic	0.983
USH2A	O75445-1.3	D434G	Pathogenic	0.822
USH2A	O75445-1.3	D434H	Pathogenic	0.892
USH2A	O75445-1.3	D434I	Pathogenic	0.988
USH2A	O75445-1.3	D434K	Pathogenic	0.773
USH2A	O75445-1.3	D434L	Pathogenic	0.994
USH2A	O75445-1.3	D434M	Pathogenic	0.984
USH2A	O75445-1.3	D434N	Pathogenic	0.69
USH2A	O75445-1.3	D434P	Pathogenic	0.962
USH2A	O75445-1.3	D434Q	Pathogenic	0.775
USH2A	O75445-1.3	D434R	Pathogenic	0.838
USH2A	O75445-1.3	D434S	Pathogenic	0.816
USH2A	O75445-1.3	D434T	Pathogenic	0.951
USH2A	O75445-1.3	D434V	Pathogenic	0.991
USH2A	O75445-1.3	D434W	Pathogenic	0.985
USH2A	O75445-1.3	D434Y	Pathogenic	0.969
USH2A	O75445-1.3	S435A	Pathogenic	0.694
USH2A	O75445-1.3	S435C	Pathogenic	0.93
USH2A	O75445-1.3	S435D	Pathogenic	0.81
USH2A	O75445-1.3	S435E	Pathogenic	0.692
USH2A	O75445-1.3	S435F	Pathogenic	0.903
USH2A	O75445-1.3	S435G	Pathogenic	0.707
USH2A	O75445-1.3	S435H	Pathogenic	0.756
USH2A	O75445-1.3	S435I	Pathogenic	0.93
USH2A	O75445-1.3	S435K	Pathogenic	0.537
USH2A	O75445-1.3	S435L	Pathogenic	0.927
USH2A	O75445-1.3	S435M	Pathogenic	0.815
USH2A	O75445-1.3	S435N	Pathogenic	0.594
USH2A	O75445-1.3	S435P	Pathogenic	0.911
USH2A	O75445-1.3	S435Q	Pathogenic	0.608
USH2A	O75445-1.3	S435R	Pathogenic	0.637
USH2A	O75445-1.3	S435T	Pathogenic	0.585
USH2A	O75445-1.3	S435V	Pathogenic	0.948
USH2A	O75445-1.3	S435W	Pathogenic	0.916
USH2A	O75445-1.3	S435Y	Pathogenic	0.836
USH2A	O75445-1.3	V436A	Pathogenic	0.798
USH2A	O75445-1.3	V436C	Pathogenic	0.922
USH2A	O75445-1.3	V436D	Pathogenic	0.994
USH2A	O75445-1.3	V436E	Pathogenic	0.99
USH2A	O75445-1.3	V436F	Pathogenic	0.908
USH2A	O75445-1.3	V436G	Pathogenic	0.967
USH2A	O75445-1.3	V436H	Pathogenic	0.991
USH2A	O75445-1.3	V436I	Neutral	0.342
USH2A	O75445-1.3	V436K	Pathogenic	0.981
USH2A	O75445-1.3	V436L	Pathogenic	0.72
USH2A	O75445-1.3	V436M	Pathogenic	0.671
USH2A	O75445-1.3	V436N	Pathogenic	0.995
USH2A	O75445-1.3	V436P	Pathogenic	0.972
USH2A	O75445-1.3	V436Q	Pathogenic	0.985
USH2A	O75445-1.3	V436R	Pathogenic	0.987
USH2A	O75445-1.3	V436S	Pathogenic	0.967
USH2A	O75445-1.3	V436T	Pathogenic	0.903
USH2A	O75445-1.3	V436W	Pathogenic	0.963
USH2A	O75445-1.3	V436Y	Pathogenic	0.874
USH2A	O75445-1.3	N437A	Pathogenic	0.974
USH2A	O75445-1.3	N437C	Pathogenic	0.995
USH2A	O75445-1.3	N437D	Pathogenic	0.823
USH2A	O75445-1.3	N437E	Pathogenic	0.885
USH2A	O75445-1.3	N437F	Pathogenic	0.992
USH2A	O75445-1.3	N437G	Pathogenic	0.768
USH2A	O75445-1.3	N437H	Pathogenic	0.781
USH2A	O75445-1.3	N437I	Pathogenic	0.995
USH2A	O75445-1.3	N437K	Pathogenic	0.799
USH2A	O75445-1.3	N437L	Pathogenic	0.994
USH2A	O75445-1.3	N437M	Pathogenic	0.984
USH2A	O75445-1.3	N437P	Pathogenic	0.99
USH2A	O75445-1.3	N437Q	Pathogenic	0.886
USH2A	O75445-1.3	N437R	Pathogenic	0.725
USH2A	O75445-1.3	N437S	Pathogenic	0.761
USH2A	O75445-1.3	N437T	Pathogenic	0.941
USH2A	O75445-1.3	N437V	Pathogenic	0.996
USH2A	O75445-1.3	N437W	Pathogenic	0.993
USH2A	O75445-1.3	N437Y	Pathogenic	0.968
USH2A	O75445-1.3	C438A	Pathogenic	0.956
USH2A	O75445-1.3	C438D	Pathogenic	0.999
USH2A	O75445-1.3	C438E	Pathogenic	0.999
USH2A	O75445-1.3	C438F	Pathogenic	0.979
USH2A	O75445-1.3	C438G	Pathogenic	0.994
USH2A	O75445-1.3	C438H	Pathogenic	0.995
USH2A	O75445-1.3	C438I	Pathogenic	0.967
USH2A	O75445-1.3	C438K	Pathogenic	0.995
USH2A	O75445-1.3	C438L	Pathogenic	0.965
USH2A	O75445-1.3	C438M	Pathogenic	0.956
USH2A	O75445-1.3	C438N	Pathogenic	0.998
USH2A	O75445-1.3	C438P	Pathogenic	0.997
USH2A	O75445-1.3	C438Q	Pathogenic	0.996
USH2A	O75445-1.3	C438R	Pathogenic	0.992
USH2A	O75445-1.3	C438S	Pathogenic	0.986
USH2A	O75445-1.3	C438T	Pathogenic	0.987
USH2A	O75445-1.3	C438V	Pathogenic	0.976
USH2A	O75445-1.3	C438W	Pathogenic	0.959
USH2A	O75445-1.3	C438Y	Pathogenic	0.963
USH2A	O75445-1.3	L439A	Neutral	0.473
USH2A	O75445-1.3	L439C	Pathogenic	0.542
USH2A	O75445-1.3	L439D	Pathogenic	0.975
USH2A	O75445-1.3	L439E	Pathogenic	0.966
USH2A	O75445-1.3	L439F	Neutral	0.474
USH2A	O75445-1.3	L439G	Pathogenic	0.871
USH2A	O75445-1.3	L439H	Pathogenic	0.963
USH2A	O75445-1.3	L439I	Neutral	0.198
USH2A	O75445-1.3	L439K	Pathogenic	0.945
USH2A	O75445-1.3	L439M	Neutral	0.229
USH2A	O75445-1.3	L439N	Pathogenic	0.949
USH2A	O75445-1.3	L439P	Pathogenic	0.889
USH2A	O75445-1.3	L439Q	Pathogenic	0.923
USH2A	O75445-1.3	L439R	Pathogenic	0.919
USH2A	O75445-1.3	L439S	Pathogenic	0.747
USH2A	O75445-1.3	L439T	Pathogenic	0.68
USH2A	O75445-1.3	L439V	Neutral	0.271
USH2A	O75445-1.3	L439W	Pathogenic	0.706
USH2A	O75445-1.3	L439Y	Pathogenic	0.701
USH2A	O75445-1.3	Q440A	Pathogenic	0.909
USH2A	O75445-1.3	Q440C	Pathogenic	0.993
USH2A	O75445-1.3	Q440D	Pathogenic	0.905
USH2A	O75445-1.3	Q440E	Pathogenic	0.754
USH2A	O75445-1.3	Q440F	Pathogenic	0.996
USH2A	O75445-1.3	Q440G	Pathogenic	0.914
USH2A	O75445-1.3	Q440H	Pathogenic	0.941
USH2A	O75445-1.3	Q440I	Pathogenic	0.997
USH2A	O75445-1.3	Q440K	Pathogenic	0.833
USH2A	O75445-1.3	Q440L	Pathogenic	0.993
USH2A	O75445-1.3	Q440M	Pathogenic	0.958
USH2A	O75445-1.3	Q440N	Pathogenic	0.912
USH2A	O75445-1.3	Q440P	Pathogenic	0.963
USH2A	O75445-1.3	Q440R	Pathogenic	0.768
USH2A	O75445-1.3	Q440S	Pathogenic	0.817
USH2A	O75445-1.3	Q440T	Pathogenic	0.957
USH2A	O75445-1.3	Q440V	Pathogenic	0.992
USH2A	O75445-1.3	Q440W	Pathogenic	0.983
USH2A	O75445-1.3	Q440Y	Pathogenic	0.963
USH2A	O75445-1.3	L441A	Pathogenic	0.535
USH2A	O75445-1.3	L441C	Pathogenic	0.602
USH2A	O75445-1.3	L441D	Pathogenic	0.981
USH2A	O75445-1.3	L441E	Pathogenic	0.974
USH2A	O75445-1.3	L441F	Pathogenic	0.535
USH2A	O75445-1.3	L441G	Pathogenic	0.896
USH2A	O75445-1.3	L441H	Pathogenic	0.971
USH2A	O75445-1.3	L441I	Neutral	0.241
USH2A	O75445-1.3	L441K	Pathogenic	0.956
USH2A	O75445-1.3	L441M	Neutral	0.275
USH2A	O75445-1.3	L441N	Pathogenic	0.96
USH2A	O75445-1.3	L441P	Pathogenic	0.911
USH2A	O75445-1.3	L441Q	Pathogenic	0.939
USH2A	O75445-1.3	L441R	Pathogenic	0.936
USH2A	O75445-1.3	L441S	Pathogenic	0.79
USH2A	O75445-1.3	L441T	Pathogenic	0.731
USH2A	O75445-1.3	L441V	Neutral	0.322
USH2A	O75445-1.3	L441W	Pathogenic	0.755
USH2A	O75445-1.3	L441Y	Pathogenic	0.75
USH2A	O75445-1.3	S442A	Neutral	0.064
USH2A	O75445-1.3	S442C	Neutral	0.283
USH2A	O75445-1.3	S442D	Neutral	0.113
USH2A	O75445-1.3	S442E	Neutral	0.063
USH2A	O75445-1.3	S442F	Neutral	0.218
USH2A	O75445-1.3	S442G	Neutral	0.067
USH2A	O75445-1.3	S442H	Neutral	0.085
USH2A	O75445-1.3	S442I	Neutral	0.286
USH2A	O75445-1.3	S442K	Neutral	0.034
USH2A	O75445-1.3	S442L	Neutral	0.276
USH2A	O75445-1.3	S442M	Neutral	0.117
USH2A	O75445-1.3	S442N	Neutral	0.042
USH2A	O75445-1.3	S442P	Neutral	0.234
USH2A	O75445-1.3	S442Q	Neutral	0.044
USH2A	O75445-1.3	S442R	Neutral	0.05
USH2A	O75445-1.3	S442T	Neutral	0.041
USH2A	O75445-1.3	S442V	Neutral	0.355
USH2A	O75445-1.3	S442W	Neutral	0.246
USH2A	O75445-1.3	S442Y	Neutral	0.132
USH2A	O75445-1.3	N443A	Neutral	0.145
USH2A	O75445-1.3	N443C	Neutral	0.499
USH2A	O75445-1.3	N443D	Neutral	0.021
USH2A	O75445-1.3	N443E	Neutral	0.034
USH2A	O75445-1.3	N443F	Neutral	0.369
USH2A	O75445-1.3	N443G	Neutral	0.015
USH2A	O75445-1.3	N443H	Neutral	0.016
USH2A	O75445-1.3	N443I	Neutral	0.457
USH2A	O75445-1.3	N443K	Neutral	0.018
USH2A	O75445-1.3	N443L	Neutral	0.444
USH2A	O75445-1.3	N443M	Neutral	0.217
USH2A	O75445-1.3	N443P	Neutral	0.303
USH2A	O75445-1.3	N443Q	Neutral	0.034
USH2A	O75445-1.3	N443R	Neutral	0.012
USH2A	O75445-1.3	N443S	Neutral	0.014
USH2A	O75445-1.3	N443T	Neutral	0.068
USH2A	O75445-1.3	N443V	Pathogenic	0.536
USH2A	O75445-1.3	N443W	Neutral	0.406
USH2A	O75445-1.3	N443Y	Neutral	0.123
USH2A	O75445-1.3	F444A	Neutral	0.453
USH2A	O75445-1.3	F444C	Pathogenic	0.521
USH2A	O75445-1.3	F444D	Pathogenic	0.875
USH2A	O75445-1.3	F444E	Pathogenic	0.921
USH2A	O75445-1.3	F444G	Pathogenic	0.545
USH2A	O75445-1.3	F444H	Pathogenic	0.67
USH2A	O75445-1.3	F444I	Neutral	0.323
USH2A	O75445-1.3	F444K	Pathogenic	0.97
USH2A	O75445-1.3	F444L	Neutral	0.331
USH2A	O75445-1.3	F444M	Neutral	0.385
USH2A	O75445-1.3	F444N	Pathogenic	0.883
USH2A	O75445-1.3	F444P	Pathogenic	0.88
USH2A	O75445-1.3	F444Q	Pathogenic	0.917
USH2A	O75445-1.3	F444R	Pathogenic	0.955
USH2A	O75445-1.3	F444S	Pathogenic	0.543
USH2A	O75445-1.3	F444T	Pathogenic	0.662
USH2A	O75445-1.3	F444V	Neutral	0.439
USH2A	O75445-1.3	F444W	Neutral	0.131
USH2A	O75445-1.3	F444Y	Neutral	0.066
USH2A	O75445-1.3	T445A	Neutral	0.065
USH2A	O75445-1.3	T445C	Neutral	0.291
USH2A	O75445-1.3	T445D	Neutral	0.359
USH2A	O75445-1.3	T445E	Neutral	0.251
USH2A	O75445-1.3	T445F	Neutral	0.313
USH2A	O75445-1.3	T445G	Neutral	0.18
USH2A	O75445-1.3	T445H	Neutral	0.281
USH2A	O75445-1.3	T445I	Neutral	0.222
USH2A	O75445-1.3	T445K	Neutral	0.148
USH2A	O75445-1.3	T445L	Neutral	0.214
USH2A	O75445-1.3	T445M	Neutral	0.177
USH2A	O75445-1.3	T445N	Neutral	0.179
USH2A	O75445-1.3	T445P	Neutral	0.291
USH2A	O75445-1.3	T445Q	Neutral	0.188
USH2A	O75445-1.3	T445R	Neutral	0.103
USH2A	O75445-1.3	T445S	Neutral	0.04
USH2A	O75445-1.3	T445V	Neutral	0.147
USH2A	O75445-1.3	T445W	Neutral	0.189
USH2A	O75445-1.3	T445Y	Neutral	0.199
USH2A	O75445-1.3	P446A	Pathogenic	0.915
USH2A	O75445-1.3	P446C	Pathogenic	0.99
USH2A	O75445-1.3	P446D	Pathogenic	0.974
USH2A	O75445-1.3	P446E	Pathogenic	0.951
USH2A	O75445-1.3	P446F	Pathogenic	0.989
USH2A	O75445-1.3	P446G	Pathogenic	0.94
USH2A	O75445-1.3	P446H	Pathogenic	0.958
USH2A	O75445-1.3	P446I	Pathogenic	0.982
USH2A	O75445-1.3	P446K	Pathogenic	0.91
USH2A	O75445-1.3	P446L	Pathogenic	0.981
USH2A	O75445-1.3	P446M	Pathogenic	0.948
USH2A	O75445-1.3	P446N	Pathogenic	0.985
USH2A	O75445-1.3	P446Q	Pathogenic	0.931
USH2A	O75445-1.3	P446R	Pathogenic	0.939
USH2A	O75445-1.3	P446S	Pathogenic	0.939
USH2A	O75445-1.3	P446T	Pathogenic	0.955
USH2A	O75445-1.3	P446V	Pathogenic	0.971
USH2A	O75445-1.3	P446W	Pathogenic	0.978
USH2A	O75445-1.3	P446Y	Pathogenic	0.955
USH2A	O75445-1.3	Y447A	Pathogenic	0.575
USH2A	O75445-1.3	Y447C	Pathogenic	0.646
USH2A	O75445-1.3	Y447D	Pathogenic	0.919
USH2A	O75445-1.3	Y447E	Pathogenic	0.893
USH2A	O75445-1.3	Y447F	Neutral	0.175
USH2A	O75445-1.3	Y447G	Pathogenic	0.662
USH2A	O75445-1.3	Y447H	Neutral	0.219
USH2A	O75445-1.3	Y447I	Pathogenic	0.803
USH2A	O75445-1.3	Y447K	Pathogenic	0.958
USH2A	O75445-1.3	Y447L	Pathogenic	0.794
USH2A	O75445-1.3	Y447M	Pathogenic	0.754
USH2A	O75445-1.3	Y447N	Pathogenic	0.844
USH2A	O75445-1.3	Y447P	Pathogenic	0.841
USH2A	O75445-1.3	Y447Q	Pathogenic	0.777
USH2A	O75445-1.3	Y447R	Pathogenic	0.957
USH2A	O75445-1.3	Y447S	Pathogenic	0.661
USH2A	O75445-1.3	Y447T	Pathogenic	0.762
USH2A	O75445-1.3	Y447V	Pathogenic	0.623
USH2A	O75445-1.3	Y447W	Neutral	0.266
USH2A	O75445-1.3	S448A	Neutral	0.487
USH2A	O75445-1.3	S448C	Pathogenic	0.847
USH2A	O75445-1.3	S448D	Pathogenic	0.641
USH2A	O75445-1.3	S448E	Neutral	0.484
USH2A	O75445-1.3	S448F	Pathogenic	0.796
USH2A	O75445-1.3	S448G	Pathogenic	0.502
USH2A	O75445-1.3	S448H	Pathogenic	0.564
USH2A	O75445-1.3	S448I	Pathogenic	0.848
USH2A	O75445-1.3	S448K	Neutral	0.326
USH2A	O75445-1.3	S448L	Pathogenic	0.842
USH2A	O75445-1.3	S448M	Pathogenic	0.648
USH2A	O75445-1.3	S448N	Neutral	0.38
USH2A	O75445-1.3	S448P	Pathogenic	0.81
USH2A	O75445-1.3	S448Q	Neutral	0.394
USH2A	O75445-1.3	S448R	Neutral	0.423
USH2A	O75445-1.3	S448T	Neutral	0.371
USH2A	O75445-1.3	S448V	Pathogenic	0.885
USH2A	O75445-1.3	S448W	Pathogenic	0.82
USH2A	O75445-1.3	S448Y	Pathogenic	0.681
USH2A	O75445-1.3	R449A	Neutral	0.047
USH2A	O75445-1.3	R449C	Neutral	0.396
USH2A	O75445-1.3	R449D	Neutral	0.124
USH2A	O75445-1.3	R449E	Neutral	0.049
USH2A	O75445-1.3	R449F	Pathogenic	0.825
USH2A	O75445-1.3	R449G	Neutral	0.049
USH2A	O75445-1.3	R449H	Neutral	0.092
USH2A	O75445-1.3	R449I	Pathogenic	0.77
USH2A	O75445-1.3	R449K	Neutral	0.019
USH2A	O75445-1.3	R449L	Pathogenic	0.581
USH2A	O75445-1.3	R449M	Neutral	0.325
USH2A	O75445-1.3	R449N	Neutral	0.033
USH2A	O75445-1.3	R449P	Neutral	0.223
USH2A	O75445-1.3	R449Q	Neutral	0.032
USH2A	O75445-1.3	R449S	Neutral	0.048
USH2A	O75445-1.3	R449T	Neutral	0.099
USH2A	O75445-1.3	R449V	Pathogenic	0.575
USH2A	O75445-1.3	R449W	Pathogenic	0.848
USH2A	O75445-1.3	R449Y	Pathogenic	0.624
USH2A	O75445-1.3	G450A	Pathogenic	0.878
USH2A	O75445-1.3	G450C	Pathogenic	0.985
USH2A	O75445-1.3	G450D	Pathogenic	0.906
USH2A	O75445-1.3	G450E	Pathogenic	0.92
USH2A	O75445-1.3	G450F	Pathogenic	0.953
USH2A	O75445-1.3	G450H	Pathogenic	0.87
USH2A	O75445-1.3	G450I	Pathogenic	0.985
USH2A	O75445-1.3	G450K	Pathogenic	0.856
USH2A	O75445-1.3	G450L	Pathogenic	0.984
USH2A	O75445-1.3	G450M	Pathogenic	0.956
USH2A	O75445-1.3	G450N	Pathogenic	0.767
USH2A	O75445-1.3	G450P	Pathogenic	0.957
USH2A	O75445-1.3	G450Q	Pathogenic	0.889
USH2A	O75445-1.3	G450R	Pathogenic	0.798
USH2A	O75445-1.3	G450S	Pathogenic	0.839
USH2A	O75445-1.3	G450T	Pathogenic	0.941
USH2A	O75445-1.3	G450V	Pathogenic	0.976
USH2A	O75445-1.3	G450W	Pathogenic	0.819
USH2A	O75445-1.3	G450Y	Pathogenic	0.917
USH2A	O75445-1.3	N451A	Pathogenic	0.634
USH2A	O75445-1.3	N451C	Pathogenic	0.911
USH2A	O75445-1.3	N451D	Neutral	0.179
USH2A	O75445-1.3	N451E	Neutral	0.265
USH2A	O75445-1.3	N451F	Pathogenic	0.857
USH2A	O75445-1.3	N451G	Neutral	0.134
USH2A	O75445-1.3	N451H	Neutral	0.143
USH2A	O75445-1.3	N451I	Pathogenic	0.896
USH2A	O75445-1.3	N451K	Neutral	0.157
USH2A	O75445-1.3	N451L	Pathogenic	0.891
USH2A	O75445-1.3	N451M	Pathogenic	0.739
USH2A	O75445-1.3	N451P	Pathogenic	0.817
USH2A	O75445-1.3	N451Q	Neutral	0.267
USH2A	O75445-1.3	N451R	Neutral	0.11
USH2A	O75445-1.3	N451S	Neutral	0.13
USH2A	O75445-1.3	N451T	Neutral	0.428
USH2A	O75445-1.3	N451V	Pathogenic	0.922
USH2A	O75445-1.3	N451W	Pathogenic	0.875
USH2A	O75445-1.3	N451Y	Pathogenic	0.589
USH2A	O75445-1.3	V452A	Neutral	0.131
USH2A	O75445-1.3	V452C	Neutral	0.312
USH2A	O75445-1.3	V452D	Pathogenic	0.869
USH2A	O75445-1.3	V452E	Pathogenic	0.789
USH2A	O75445-1.3	V452F	Neutral	0.274
USH2A	O75445-1.3	V452G	Pathogenic	0.532
USH2A	O75445-1.3	V452H	Pathogenic	0.814
USH2A	O75445-1.3	V452I	Neutral	0.019
USH2A	O75445-1.3	V452K	Pathogenic	0.66
USH2A	O75445-1.3	V452L	Neutral	0.09
USH2A	O75445-1.3	V452M	Neutral	0.072
USH2A	O75445-1.3	V452N	Pathogenic	0.877
USH2A	O75445-1.3	V452P	Pathogenic	0.573
USH2A	O75445-1.3	V452Q	Pathogenic	0.722
USH2A	O75445-1.3	V452R	Pathogenic	0.746
USH2A	O75445-1.3	V452S	Pathogenic	0.531
USH2A	O75445-1.3	V452T	Neutral	0.263
USH2A	O75445-1.3	V452W	Pathogenic	0.501
USH2A	O75445-1.3	V452Y	Neutral	0.21
USH2A	O75445-1.3	T453A	Pathogenic	0.798
USH2A	O75445-1.3	T453C	Pathogenic	0.959
USH2A	O75445-1.3	T453D	Pathogenic	0.969
USH2A	O75445-1.3	T453E	Pathogenic	0.95
USH2A	O75445-1.3	T453F	Pathogenic	0.963
USH2A	O75445-1.3	T453G	Pathogenic	0.925
USH2A	O75445-1.3	T453H	Pathogenic	0.957
USH2A	O75445-1.3	T453I	Pathogenic	0.942
USH2A	O75445-1.3	T453K	Pathogenic	0.907
USH2A	O75445-1.3	T453L	Pathogenic	0.939
USH2A	O75445-1.3	T453M	Pathogenic	0.924
USH2A	O75445-1.3	T453N	Pathogenic	0.925
USH2A	O75445-1.3	T453P	Pathogenic	0.959
USH2A	O75445-1.3	T453Q	Pathogenic	0.929
USH2A	O75445-1.3	T453R	Pathogenic	0.867
USH2A	O75445-1.3	T453S	Pathogenic	0.703
USH2A	O75445-1.3	T453V	Pathogenic	0.907
USH2A	O75445-1.3	T453W	Pathogenic	0.93
USH2A	O75445-1.3	T453Y	Pathogenic	0.934
USH2A	O75445-1.3	F454A	Pathogenic	0.966
USH2A	O75445-1.3	F454C	Pathogenic	0.974
USH2A	O75445-1.3	F454D	Pathogenic	0.996
USH2A	O75445-1.3	F454E	Pathogenic	0.998
USH2A	O75445-1.3	F454G	Pathogenic	0.977
USH2A	O75445-1.3	F454H	Pathogenic	0.986
USH2A	O75445-1.3	F454I	Pathogenic	0.943
USH2A	O75445-1.3	F454K	Pathogenic	0.999
USH2A	O75445-1.3	F454L	Pathogenic	0.945
USH2A	O75445-1.3	F454M	Pathogenic	0.956
USH2A	O75445-1.3	F454N	Pathogenic	0.996
USH2A	O75445-1.3	F454P	Pathogenic	0.996
USH2A	O75445-1.3	F454Q	Pathogenic	0.997
USH2A	O75445-1.3	F454R	Pathogenic	0.999
USH2A	O75445-1.3	F454S	Pathogenic	0.976
USH2A	O75445-1.3	F454T	Pathogenic	0.986
USH2A	O75445-1.3	F454V	Pathogenic	0.965
USH2A	O75445-1.3	F454W	Pathogenic	0.84
USH2A	O75445-1.3	F454Y	Pathogenic	0.711
USH2A	O75445-1.3	S455A	Neutral	0.459
USH2A	O75445-1.3	S455C	Pathogenic	0.832
USH2A	O75445-1.3	S455D	Pathogenic	0.616
USH2A	O75445-1.3	S455E	Neutral	0.457
USH2A	O75445-1.3	S455F	Pathogenic	0.778
USH2A	O75445-1.3	S455G	Neutral	0.475
USH2A	O75445-1.3	S455H	Pathogenic	0.537
USH2A	O75445-1.3	S455I	Pathogenic	0.834
USH2A	O75445-1.3	S455K	Neutral	0.303
USH2A	O75445-1.3	S455L	Pathogenic	0.827
USH2A	O75445-1.3	S455M	Pathogenic	0.623
USH2A	O75445-1.3	S455N	Neutral	0.355
USH2A	O75445-1.3	S455P	Pathogenic	0.792
USH2A	O75445-1.3	S455Q	Neutral	0.368
USH2A	O75445-1.3	S455R	Neutral	0.397
USH2A	O75445-1.3	S455T	Neutral	0.346
USH2A	O75445-1.3	S455V	Pathogenic	0.873
USH2A	O75445-1.3	S455W	Pathogenic	0.803
USH2A	O75445-1.3	S455Y	Pathogenic	0.656
USH2A	O75445-1.3	I456A	Neutral	0.156
USH2A	O75445-1.3	I456C	Neutral	0.195
USH2A	O75445-1.3	I456D	Pathogenic	0.78
USH2A	O75445-1.3	I456E	Pathogenic	0.856
USH2A	O75445-1.3	I456F	Neutral	0.145
USH2A	O75445-1.3	I456G	Pathogenic	0.582
USH2A	O75445-1.3	I456H	Pathogenic	0.844
USH2A	O75445-1.3	I456K	Pathogenic	0.889
USH2A	O75445-1.3	I456L	Neutral	0.046
USH2A	O75445-1.3	I456M	Neutral	0.122
USH2A	O75445-1.3	I456N	Pathogenic	0.793
USH2A	O75445-1.3	I456P	Pathogenic	0.621
USH2A	O75445-1.3	I456Q	Pathogenic	0.85
USH2A	O75445-1.3	I456R	Pathogenic	0.842
USH2A	O75445-1.3	I456S	Neutral	0.377
USH2A	O75445-1.3	I456T	Neutral	0.304
USH2A	O75445-1.3	I456V	Neutral	0.014
USH2A	O75445-1.3	I456W	Pathogenic	0.505
USH2A	O75445-1.3	I456Y	Neutral	0.325
USH2A	O75445-1.3	L457A	Pathogenic	0.894
USH2A	O75445-1.3	L457C	Pathogenic	0.917
USH2A	O75445-1.3	L457D	Pathogenic	0.997
USH2A	O75445-1.3	L457E	Pathogenic	0.996
USH2A	O75445-1.3	L457F	Pathogenic	0.894
USH2A	O75445-1.3	L457G	Pathogenic	0.984
USH2A	O75445-1.3	L457H	Pathogenic	0.996
USH2A	O75445-1.3	L457I	Pathogenic	0.699
USH2A	O75445-1.3	L457K	Pathogenic	0.994
USH2A	O75445-1.3	L457M	Pathogenic	0.736
USH2A	O75445-1.3	L457N	Pathogenic	0.994
USH2A	O75445-1.3	L457P	Pathogenic	0.987
USH2A	O75445-1.3	L457Q	Pathogenic	0.991
USH2A	O75445-1.3	L457R	Pathogenic	0.991
USH2A	O75445-1.3	L457S	Pathogenic	0.965
USH2A	O75445-1.3	L457T	Pathogenic	0.952
USH2A	O75445-1.3	L457V	Pathogenic	0.777
USH2A	O75445-1.3	L457W	Pathogenic	0.957
USH2A	O75445-1.3	L457Y	Pathogenic	0.956
USH2A	O75445-1.3	T458A	Neutral	0.34
USH2A	O75445-1.3	T458C	Pathogenic	0.752
USH2A	O75445-1.3	T458D	Pathogenic	0.805
USH2A	O75445-1.3	T458E	Pathogenic	0.712
USH2A	O75445-1.3	T458F	Pathogenic	0.771
USH2A	O75445-1.3	T458G	Pathogenic	0.618
USH2A	O75445-1.3	T458H	Pathogenic	0.742
USH2A	O75445-1.3	T458I	Pathogenic	0.678
USH2A	O75445-1.3	T458K	Pathogenic	0.561
USH2A	O75445-1.3	T458L	Pathogenic	0.667
USH2A	O75445-1.3	T458M	Pathogenic	0.614
USH2A	O75445-1.3	T458N	Pathogenic	0.617
USH2A	O75445-1.3	T458P	Pathogenic	0.752
USH2A	O75445-1.3	T458Q	Pathogenic	0.631
USH2A	O75445-1.3	T458R	Neutral	0.459
USH2A	O75445-1.3	T458S	Neutral	0.236
USH2A	O75445-1.3	T458V	Pathogenic	0.56
USH2A	O75445-1.3	T458W	Pathogenic	0.632
USH2A	O75445-1.3	T458Y	Pathogenic	0.647
USH2A	O75445-1.3	P459A	Pathogenic	0.797
USH2A	O75445-1.3	P459C	Pathogenic	0.972
USH2A	O75445-1.3	P459D	Pathogenic	0.931
USH2A	O75445-1.3	P459E	Pathogenic	0.877
USH2A	O75445-1.3	P459F	Pathogenic	0.97
USH2A	O75445-1.3	P459G	Pathogenic	0.85
USH2A	O75445-1.3	P459H	Pathogenic	0.893
USH2A	O75445-1.3	P459I	Pathogenic	0.952
USH2A	O75445-1.3	P459K	Pathogenic	0.786
USH2A	O75445-1.3	P459L	Pathogenic	0.95
USH2A	O75445-1.3	P459M	Pathogenic	0.869
USH2A	O75445-1.3	P459N	Pathogenic	0.96
USH2A	O75445-1.3	P459Q	Pathogenic	0.831
USH2A	O75445-1.3	P459R	Pathogenic	0.848
USH2A	O75445-1.3	P459S	Pathogenic	0.849
USH2A	O75445-1.3	P459T	Pathogenic	0.884
USH2A	O75445-1.3	P459V	Pathogenic	0.924
USH2A	O75445-1.3	P459W	Pathogenic	0.942
USH2A	O75445-1.3	P459Y	Pathogenic	0.884
USH2A	O75445-1.3	G460A	Neutral	0.128
USH2A	O75445-1.3	G460C	Pathogenic	0.57
USH2A	O75445-1.3	G460D	Neutral	0.163
USH2A	O75445-1.3	G460E	Neutral	0.19
USH2A	O75445-1.3	G460F	Neutral	0.291
USH2A	O75445-1.3	G460H	Neutral	0.12
USH2A	O75445-1.3	G460I	Pathogenic	0.574
USH2A	O75445-1.3	G460K	Neutral	0.108
USH2A	O75445-1.3	G460L	Pathogenic	0.561
USH2A	O75445-1.3	G460M	Neutral	0.307
USH2A	O75445-1.3	G460N	Neutral	0.063
USH2A	O75445-1.3	G460P	Neutral	0.31
USH2A	O75445-1.3	G460Q	Neutral	0.139
USH2A	O75445-1.3	G460R	Neutral	0.074
USH2A	O75445-1.3	G460S	Neutral	0.096
USH2A	O75445-1.3	G460T	Neutral	0.245
USH2A	O75445-1.3	G460V	Neutral	0.448
USH2A	O75445-1.3	G460W	Neutral	0.084
USH2A	O75445-1.3	G460Y	Neutral	0.183
USH2A	O75445-1.3	P461A	Pathogenic	0.728
USH2A	O75445-1.3	P461C	Pathogenic	0.96
USH2A	O75445-1.3	P461D	Pathogenic	0.903
USH2A	O75445-1.3	P461E	Pathogenic	0.83
USH2A	O75445-1.3	P461F	Pathogenic	0.956
USH2A	O75445-1.3	P461G	Pathogenic	0.795
USH2A	O75445-1.3	P461H	Pathogenic	0.851
USH2A	O75445-1.3	P461I	Pathogenic	0.932
USH2A	O75445-1.3	P461K	Pathogenic	0.716
USH2A	O75445-1.3	P461L	Pathogenic	0.929
USH2A	O75445-1.3	P461M	Pathogenic	0.819
USH2A	O75445-1.3	P461N	Pathogenic	0.943
USH2A	O75445-1.3	P461Q	Pathogenic	0.772
USH2A	O75445-1.3	P461R	Pathogenic	0.793
USH2A	O75445-1.3	P461S	Pathogenic	0.794
USH2A	O75445-1.3	P461T	Pathogenic	0.84
USH2A	O75445-1.3	P461V	Pathogenic	0.892
USH2A	O75445-1.3	P461W	Pathogenic	0.918
USH2A	O75445-1.3	P461Y	Pathogenic	0.84
USH2A	O75445-1.3	N462A	Neutral	0.412
USH2A	O75445-1.3	N462C	Pathogenic	0.805
USH2A	O75445-1.3	N462D	Neutral	0.081
USH2A	O75445-1.3	N462E	Neutral	0.127
USH2A	O75445-1.3	N462F	Pathogenic	0.708
USH2A	O75445-1.3	N462G	Neutral	0.059
USH2A	O75445-1.3	N462H	Neutral	0.063
USH2A	O75445-1.3	N462I	Pathogenic	0.776
USH2A	O75445-1.3	N462K	Neutral	0.07
USH2A	O75445-1.3	N462L	Pathogenic	0.767
USH2A	O75445-1.3	N462M	Pathogenic	0.534
USH2A	O75445-1.3	N462P	Pathogenic	0.643
USH2A	O75445-1.3	N462Q	Neutral	0.128
USH2A	O75445-1.3	N462R	Neutral	0.048
USH2A	O75445-1.3	N462S	Neutral	0.057
USH2A	O75445-1.3	N462T	Neutral	0.232
USH2A	O75445-1.3	N462V	Pathogenic	0.827
USH2A	O75445-1.3	N462W	Pathogenic	0.739
USH2A	O75445-1.3	N462Y	Neutral	0.367
USH2A	O75445-1.3	Y463A	Neutral	0.006
USH2A	O75445-1.3	Y463C	Neutral	0.009
USH2A	O75445-1.3	Y463D	Neutral	0.052
USH2A	O75445-1.3	Y463E	Neutral	0.039
USH2A	O75445-1.3	Y463F	Neutral	0.001
USH2A	O75445-1.3	Y463G	Neutral	0.009
USH2A	O75445-1.3	Y463H	Neutral	0.001
USH2A	O75445-1.3	Y463I	Neutral	0.019
USH2A	O75445-1.3	Y463K	Neutral	0.099
USH2A	O75445-1.3	Y463L	Neutral	0.018
USH2A	O75445-1.3	Y463M	Neutral	0.015
USH2A	O75445-1.3	Y463N	Neutral	0.025
USH2A	O75445-1.3	Y463P	Neutral	0.025
USH2A	O75445-1.3	Y463Q	Neutral	0.016
USH2A	O75445-1.3	Y463R	Neutral	0.097
USH2A	O75445-1.3	Y463S	Neutral	0.009
USH2A	O75445-1.3	Y463T	Neutral	0.015
USH2A	O75445-1.3	Y463V	Neutral	0.008
USH2A	O75445-1.3	Y463W	Neutral	0.002
USH2A	O75445-1.3	R464A	Pathogenic	0.833
USH2A	O75445-1.3	R464C	Pathogenic	0.985
USH2A	O75445-1.3	R464D	Pathogenic	0.935
USH2A	O75445-1.3	R464E	Pathogenic	0.84
USH2A	O75445-1.3	R464F	Pathogenic	0.998
USH2A	O75445-1.3	R464G	Pathogenic	0.841
USH2A	O75445-1.3	R464H	Pathogenic	0.911
USH2A	O75445-1.3	R464I	Pathogenic	0.997
USH2A	O75445-1.3	R464K	Pathogenic	0.661
USH2A	O75445-1.3	R464L	Pathogenic	0.993
USH2A	O75445-1.3	R464M	Pathogenic	0.98
USH2A	O75445-1.3	R464N	Pathogenic	0.779
USH2A	O75445-1.3	R464P	Pathogenic	0.967
USH2A	O75445-1.3	R464Q	Pathogenic	0.769
USH2A	O75445-1.3	R464S	Pathogenic	0.836
USH2A	O75445-1.3	R464T	Pathogenic	0.918
USH2A	O75445-1.3	R464V	Pathogenic	0.993
USH2A	O75445-1.3	R464W	Pathogenic	0.998
USH2A	O75445-1.3	R464Y	Pathogenic	0.994
USH2A	O75445-1.3	P465A	Pathogenic	0.898
USH2A	O75445-1.3	P465C	Pathogenic	0.987
USH2A	O75445-1.3	P465D	Pathogenic	0.968
USH2A	O75445-1.3	P465E	Pathogenic	0.941
USH2A	O75445-1.3	P465F	Pathogenic	0.986
USH2A	O75445-1.3	P465G	Pathogenic	0.927
USH2A	O75445-1.3	P465H	Pathogenic	0.949
USH2A	O75445-1.3	P465I	Pathogenic	0.978
USH2A	O75445-1.3	P465K	Pathogenic	0.892
USH2A	O75445-1.3	P465L	Pathogenic	0.977
USH2A	O75445-1.3	P465M	Pathogenic	0.937
USH2A	O75445-1.3	P465N	Pathogenic	0.982
USH2A	O75445-1.3	P465Q	Pathogenic	0.917
USH2A	O75445-1.3	P465R	Pathogenic	0.926
USH2A	O75445-1.3	P465S	Pathogenic	0.927
USH2A	O75445-1.3	P465T	Pathogenic	0.945
USH2A	O75445-1.3	P465V	Pathogenic	0.965
USH2A	O75445-1.3	P465W	Pathogenic	0.974
USH2A	O75445-1.3	P465Y	Pathogenic	0.945
USH2A	O75445-1.3	G466A	Pathogenic	0.84
USH2A	O75445-1.3	G466C	Pathogenic	0.979
USH2A	O75445-1.3	G466D	Pathogenic	0.875
USH2A	O75445-1.3	G466E	Pathogenic	0.893
USH2A	O75445-1.3	G466F	Pathogenic	0.936
USH2A	O75445-1.3	G466H	Pathogenic	0.83
USH2A	O75445-1.3	G466I	Pathogenic	0.98
USH2A	O75445-1.3	G466K	Pathogenic	0.813
USH2A	O75445-1.3	G466L	Pathogenic	0.979
USH2A	O75445-1.3	G466M	Pathogenic	0.941
USH2A	O75445-1.3	G466N	Pathogenic	0.706
USH2A	O75445-1.3	G466P	Pathogenic	0.941
USH2A	O75445-1.3	G466Q	Pathogenic	0.853
USH2A	O75445-1.3	G466R	Pathogenic	0.742
USH2A	O75445-1.3	G466S	Pathogenic	0.791
USH2A	O75445-1.3	G466T	Pathogenic	0.921
USH2A	O75445-1.3	G466V	Pathogenic	0.967
USH2A	O75445-1.3	G466W	Pathogenic	0.767
USH2A	O75445-1.3	G466Y	Pathogenic	0.889
USH2A	O75445-1.3	Y467A	Pathogenic	0.907
USH2A	O75445-1.3	Y467C	Pathogenic	0.929
USH2A	O75445-1.3	Y467D	Pathogenic	0.988
USH2A	O75445-1.3	Y467E	Pathogenic	0.984
USH2A	O75445-1.3	Y467F	Pathogenic	0.604
USH2A	O75445-1.3	Y467G	Pathogenic	0.934
USH2A	O75445-1.3	Y467H	Pathogenic	0.669
USH2A	O75445-1.3	Y467I	Pathogenic	0.967
USH2A	O75445-1.3	Y467K	Pathogenic	0.994
USH2A	O75445-1.3	Y467L	Pathogenic	0.965
USH2A	O75445-1.3	Y467M	Pathogenic	0.957
USH2A	O75445-1.3	Y467N	Pathogenic	0.975
USH2A	O75445-1.3	Y467P	Pathogenic	0.974
USH2A	O75445-1.3	Y467Q	Pathogenic	0.962
USH2A	O75445-1.3	Y467R	Pathogenic	0.994
USH2A	O75445-1.3	Y467S	Pathogenic	0.934
USH2A	O75445-1.3	Y467T	Pathogenic	0.959
USH2A	O75445-1.3	Y467V	Pathogenic	0.923
USH2A	O75445-1.3	Y467W	Pathogenic	0.724
USH2A	O75445-1.3	N468A	Pathogenic	0.933
USH2A	O75445-1.3	N468C	Pathogenic	0.988
USH2A	O75445-1.3	N468D	Pathogenic	0.635
USH2A	O75445-1.3	N468E	Pathogenic	0.742
USH2A	O75445-1.3	N468F	Pathogenic	0.98
USH2A	O75445-1.3	N468G	Pathogenic	0.553
USH2A	O75445-1.3	N468H	Pathogenic	0.572
USH2A	O75445-1.3	N468I	Pathogenic	0.986
USH2A	O75445-1.3	N468K	Pathogenic	0.598
USH2A	O75445-1.3	N468L	Pathogenic	0.985
USH2A	O75445-1.3	N468M	Pathogenic	0.958
USH2A	O75445-1.3	N468P	Pathogenic	0.973
USH2A	O75445-1.3	N468Q	Pathogenic	0.744
USH2A	O75445-1.3	N468R	Neutral	0.497
USH2A	O75445-1.3	N468S	Pathogenic	0.543
USH2A	O75445-1.3	N468T	Pathogenic	0.857
USH2A	O75445-1.3	N468V	Pathogenic	0.99
USH2A	O75445-1.3	N468W	Pathogenic	0.982
USH2A	O75445-1.3	N468Y	Pathogenic	0.92
USH2A	O75445-1.3	N469A	Pathogenic	0.665
USH2A	O75445-1.3	N469C	Pathogenic	0.921
USH2A	O75445-1.3	N469D	Neutral	0.2
USH2A	O75445-1.3	N469E	Neutral	0.292
USH2A	O75445-1.3	N469F	Pathogenic	0.873
USH2A	O75445-1.3	N469G	Neutral	0.151
USH2A	O75445-1.3	N469H	Neutral	0.161
USH2A	O75445-1.3	N469I	Pathogenic	0.908
USH2A	O75445-1.3	N469K	Neutral	0.176
USH2A	O75445-1.3	N469L	Pathogenic	0.904
USH2A	O75445-1.3	N469M	Pathogenic	0.765
USH2A	O75445-1.3	N469P	Pathogenic	0.836
USH2A	O75445-1.3	N469Q	Neutral	0.295
USH2A	O75445-1.3	N469R	Neutral	0.124
USH2A	O75445-1.3	N469S	Neutral	0.146
USH2A	O75445-1.3	N469T	Neutral	0.461
USH2A	O75445-1.3	N469V	Pathogenic	0.931
USH2A	O75445-1.3	N469W	Pathogenic	0.889
USH2A	O75445-1.3	N469Y	Pathogenic	0.622
USH2A	O75445-1.3	F470A	Pathogenic	0.965
USH2A	O75445-1.3	F470C	Pathogenic	0.973
USH2A	O75445-1.3	F470D	Pathogenic	0.996
USH2A	O75445-1.3	F470E	Pathogenic	0.997
USH2A	O75445-1.3	F470G	Pathogenic	0.975
USH2A	O75445-1.3	F470H	Pathogenic	0.985
USH2A	O75445-1.3	F470I	Pathogenic	0.941
USH2A	O75445-1.3	F470K	Pathogenic	0.999
USH2A	O75445-1.3	F470L	Pathogenic	0.943
USH2A	O75445-1.3	F470M	Pathogenic	0.954
USH2A	O75445-1.3	F470N	Pathogenic	0.996
USH2A	O75445-1.3	F470P	Pathogenic	0.996
USH2A	O75445-1.3	F470Q	Pathogenic	0.997
USH2A	O75445-1.3	F470R	Pathogenic	0.999
USH2A	O75445-1.3	F470S	Pathogenic	0.975
USH2A	O75445-1.3	F470T	Pathogenic	0.985
USH2A	O75445-1.3	F470V	Pathogenic	0.963
USH2A	O75445-1.3	F470W	Pathogenic	0.834
USH2A	O75445-1.3	F470Y	Pathogenic	0.701
USH2A	O75445-1.3	Y471A	Pathogenic	0.933
USH2A	O75445-1.3	Y471C	Pathogenic	0.95
USH2A	O75445-1.3	Y471D	Pathogenic	0.992
USH2A	O75445-1.3	Y471E	Pathogenic	0.989
USH2A	O75445-1.3	Y471F	Pathogenic	0.686
USH2A	O75445-1.3	Y471G	Pathogenic	0.953
USH2A	O75445-1.3	Y471H	Pathogenic	0.743
USH2A	O75445-1.3	Y471I	Pathogenic	0.977
USH2A	O75445-1.3	Y471K	Pathogenic	0.996
USH2A	O75445-1.3	Y471L	Pathogenic	0.976
USH2A	O75445-1.3	Y471M	Pathogenic	0.969
USH2A	O75445-1.3	Y471N	Pathogenic	0.982
USH2A	O75445-1.3	Y471P	Pathogenic	0.982
USH2A	O75445-1.3	Y471Q	Pathogenic	0.973
USH2A	O75445-1.3	Y471R	Pathogenic	0.996
USH2A	O75445-1.3	Y471S	Pathogenic	0.953
USH2A	O75445-1.3	Y471T	Pathogenic	0.971
USH2A	O75445-1.3	Y471V	Pathogenic	0.945
USH2A	O75445-1.3	Y471W	Pathogenic	0.79
USH2A	O75445-1.3	N472A	Pathogenic	0.886
USH2A	O75445-1.3	N472C	Pathogenic	0.978
USH2A	O75445-1.3	N472D	Neutral	0.493
USH2A	O75445-1.3	N472E	Pathogenic	0.617
USH2A	O75445-1.3	N472F	Pathogenic	0.964
USH2A	O75445-1.3	N472G	Neutral	0.409
USH2A	O75445-1.3	N472H	Neutral	0.427
USH2A	O75445-1.3	N472I	Pathogenic	0.975
USH2A	O75445-1.3	N472K	Neutral	0.454
USH2A	O75445-1.3	N472L	Pathogenic	0.973
USH2A	O75445-1.3	N472M	Pathogenic	0.927
USH2A	O75445-1.3	N472P	Pathogenic	0.952
USH2A	O75445-1.3	N472Q	Pathogenic	0.619
USH2A	O75445-1.3	N472R	Neutral	0.355
USH2A	O75445-1.3	N472S	Neutral	0.399
USH2A	O75445-1.3	N472T	Pathogenic	0.769
USH2A	O75445-1.3	N472V	Pathogenic	0.981
USH2A	O75445-1.3	N472W	Pathogenic	0.969
USH2A	O75445-1.3	N472Y	Pathogenic	0.865
USH2A	O75445-1.3	T473A	Neutral	0.32
USH2A	O75445-1.3	T473C	Pathogenic	0.734
USH2A	O75445-1.3	T473D	Pathogenic	0.79
USH2A	O75445-1.3	T473E	Pathogenic	0.692
USH2A	O75445-1.3	T473F	Pathogenic	0.754
USH2A	O75445-1.3	T473G	Pathogenic	0.596
USH2A	O75445-1.3	T473H	Pathogenic	0.724
USH2A	O75445-1.3	T473I	Pathogenic	0.658
USH2A	O75445-1.3	T473K	Pathogenic	0.538
USH2A	O75445-1.3	T473L	Pathogenic	0.646
USH2A	O75445-1.3	T473M	Pathogenic	0.591
USH2A	O75445-1.3	T473N	Pathogenic	0.595
USH2A	O75445-1.3	T473P	Pathogenic	0.734
USH2A	O75445-1.3	T473Q	Pathogenic	0.609
USH2A	O75445-1.3	T473R	Neutral	0.436
USH2A	O75445-1.3	T473S	Neutral	0.22
USH2A	O75445-1.3	T473V	Pathogenic	0.537
USH2A	O75445-1.3	T473W	Pathogenic	0.61
USH2A	O75445-1.3	T473Y	Pathogenic	0.626
USH2A	O75445-1.3	P474A	Pathogenic	0.555
USH2A	O75445-1.3	P474C	Pathogenic	0.917
USH2A	O75445-1.3	P474D	Pathogenic	0.812
USH2A	O75445-1.3	P474E	Pathogenic	0.694
USH2A	O75445-1.3	P474F	Pathogenic	0.91
USH2A	O75445-1.3	P474G	Pathogenic	0.643
USH2A	O75445-1.3	P474H	Pathogenic	0.725
USH2A	O75445-1.3	P474I	Pathogenic	0.864
USH2A	O75445-1.3	P474K	Pathogenic	0.539
USH2A	O75445-1.3	P474L	Pathogenic	0.858
USH2A	O75445-1.3	P474M	Pathogenic	0.678
USH2A	O75445-1.3	P474N	Pathogenic	0.885
USH2A	O75445-1.3	P474Q	Pathogenic	0.61
USH2A	O75445-1.3	P474R	Pathogenic	0.639
USH2A	O75445-1.3	P474S	Pathogenic	0.642
USH2A	O75445-1.3	P474T	Pathogenic	0.708
USH2A	O75445-1.3	P474V	Pathogenic	0.793
USH2A	O75445-1.3	P474W	Pathogenic	0.839
USH2A	O75445-1.3	P474Y	Pathogenic	0.708
USH2A	O75445-1.3	S475A	Neutral	0.05
USH2A	O75445-1.3	S475C	Neutral	0.236
USH2A	O75445-1.3	S475D	Neutral	0.091
USH2A	O75445-1.3	S475E	Neutral	0.05
USH2A	O75445-1.3	S475F	Neutral	0.179
USH2A	O75445-1.3	S475G	Neutral	0.053
USH2A	O75445-1.3	S475H	Neutral	0.068
USH2A	O75445-1.3	S475I	Neutral	0.238
USH2A	O75445-1.3	S475K	Neutral	0.026
USH2A	O75445-1.3	S475L	Neutral	0.229
USH2A	O75445-1.3	S475M	Neutral	0.094
USH2A	O75445-1.3	S475N	Neutral	0.033
USH2A	O75445-1.3	S475P	Neutral	0.192
USH2A	O75445-1.3	S475Q	Neutral	0.035
USH2A	O75445-1.3	S475R	Neutral	0.039
USH2A	O75445-1.3	S475T	Neutral	0.032
USH2A	O75445-1.3	S475V	Neutral	0.301
USH2A	O75445-1.3	S475W	Neutral	0.203
USH2A	O75445-1.3	S475Y	Neutral	0.107
USH2A	O75445-1.3	L476A	Pathogenic	0.868
USH2A	O75445-1.3	L476C	Pathogenic	0.896
USH2A	O75445-1.3	L476D	Pathogenic	0.997
USH2A	O75445-1.3	L476E	Pathogenic	0.995
USH2A	O75445-1.3	L476F	Pathogenic	0.868
USH2A	O75445-1.3	L476G	Pathogenic	0.98
USH2A	O75445-1.3	L476H	Pathogenic	0.995
USH2A	O75445-1.3	L476I	Pathogenic	0.644
USH2A	O75445-1.3	L476K	Pathogenic	0.992
USH2A	O75445-1.3	L476M	Pathogenic	0.685
USH2A	O75445-1.3	L476N	Pathogenic	0.993
USH2A	O75445-1.3	L476P	Pathogenic	0.983
USH2A	O75445-1.3	L476Q	Pathogenic	0.989
USH2A	O75445-1.3	L476R	Pathogenic	0.988
USH2A	O75445-1.3	L476S	Pathogenic	0.956
USH2A	O75445-1.3	L476T	Pathogenic	0.939
USH2A	O75445-1.3	L476V	Pathogenic	0.731
USH2A	O75445-1.3	L476W	Pathogenic	0.946
USH2A	O75445-1.3	L476Y	Pathogenic	0.945
USH2A	O75445-1.3	Q477A	Pathogenic	0.784
USH2A	O75445-1.3	Q477C	Pathogenic	0.98
USH2A	O75445-1.3	Q477D	Pathogenic	0.776
USH2A	O75445-1.3	Q477E	Pathogenic	0.527
USH2A	O75445-1.3	Q477F	Pathogenic	0.989
USH2A	O75445-1.3	Q477G	Pathogenic	0.794
USH2A	O75445-1.3	Q477H	Pathogenic	0.853
USH2A	O75445-1.3	Q477I	Pathogenic	0.992
USH2A	O75445-1.3	Q477K	Pathogenic	0.644
USH2A	O75445-1.3	Q477L	Pathogenic	0.982
USH2A	O75445-1.3	Q477M	Pathogenic	0.892
USH2A	O75445-1.3	Q477N	Pathogenic	0.79
USH2A	O75445-1.3	Q477P	Pathogenic	0.903
USH2A	O75445-1.3	Q477R	Pathogenic	0.546
USH2A	O75445-1.3	Q477S	Pathogenic	0.619
USH2A	O75445-1.3	Q477T	Pathogenic	0.891
USH2A	O75445-1.3	Q477V	Pathogenic	0.978
USH2A	O75445-1.3	Q477W	Pathogenic	0.953
USH2A	O75445-1.3	Q477Y	Pathogenic	0.905
USH2A	O75445-1.3	E478A	Pathogenic	0.853
USH2A	O75445-1.3	E478C	Pathogenic	0.994
USH2A	O75445-1.3	E478D	Neutral	0.412
USH2A	O75445-1.3	E478F	Pathogenic	0.991
USH2A	O75445-1.3	E478G	Pathogenic	0.86
USH2A	O75445-1.3	E478H	Pathogenic	0.87
USH2A	O75445-1.3	E478I	Pathogenic	0.993
USH2A	O75445-1.3	E478K	Pathogenic	0.58
USH2A	O75445-1.3	E478L	Pathogenic	0.993
USH2A	O75445-1.3	E478M	Pathogenic	0.98
USH2A	O75445-1.3	E478N	Pathogenic	0.804
USH2A	O75445-1.3	E478P	Pathogenic	0.937
USH2A	O75445-1.3	E478Q	Pathogenic	0.551
USH2A	O75445-1.3	E478R	Pathogenic	0.677
USH2A	O75445-1.3	E478S	Pathogenic	0.722
USH2A	O75445-1.3	E478T	Pathogenic	0.929
USH2A	O75445-1.3	E478V	Pathogenic	0.986
USH2A	O75445-1.3	E478W	Pathogenic	0.982
USH2A	O75445-1.3	E478Y	Pathogenic	0.962
USH2A	O75445-1.3	F479A	Pathogenic	0.821
USH2A	O75445-1.3	F479C	Pathogenic	0.858
USH2A	O75445-1.3	F479D	Pathogenic	0.975
USH2A	O75445-1.3	F479E	Pathogenic	0.985
USH2A	O75445-1.3	F479G	Pathogenic	0.869
USH2A	O75445-1.3	F479H	Pathogenic	0.919
USH2A	O75445-1.3	F479I	Pathogenic	0.726
USH2A	O75445-1.3	F479K	Pathogenic	0.994
USH2A	O75445-1.3	F479L	Pathogenic	0.733
USH2A	O75445-1.3	F479M	Pathogenic	0.776
USH2A	O75445-1.3	F479N	Pathogenic	0.977
USH2A	O75445-1.3	F479P	Pathogenic	0.976
USH2A	O75445-1.3	F479Q	Pathogenic	0.984
USH2A	O75445-1.3	F479R	Pathogenic	0.992
USH2A	O75445-1.3	F479S	Pathogenic	0.868
USH2A	O75445-1.3	F479T	Pathogenic	0.916
USH2A	O75445-1.3	F479V	Pathogenic	0.813
USH2A	O75445-1.3	F479W	Neutral	0.456
USH2A	O75445-1.3	F479Y	Neutral	0.281
USH2A	O75445-1.3	V480A	Pathogenic	0.508
USH2A	O75445-1.3	V480C	Pathogenic	0.756
USH2A	O75445-1.3	V480D	Pathogenic	0.978
USH2A	O75445-1.3	V480E	Pathogenic	0.962
USH2A	O75445-1.3	V480F	Pathogenic	0.72
USH2A	O75445-1.3	V480G	Pathogenic	0.886
USH2A	O75445-1.3	V480H	Pathogenic	0.968
USH2A	O75445-1.3	V480I	Neutral	0.12
USH2A	O75445-1.3	V480K	Pathogenic	0.93
USH2A	O75445-1.3	V480L	Neutral	0.403
USH2A	O75445-1.3	V480M	Neutral	0.348
USH2A	O75445-1.3	V480N	Pathogenic	0.98
USH2A	O75445-1.3	V480P	Pathogenic	0.902
USH2A	O75445-1.3	V480Q	Pathogenic	0.947
USH2A	O75445-1.3	V480R	Pathogenic	0.953
USH2A	O75445-1.3	V480S	Pathogenic	0.886
USH2A	O75445-1.3	V480T	Pathogenic	0.709
USH2A	O75445-1.3	V480W	Pathogenic	0.873
USH2A	O75445-1.3	V480Y	Pathogenic	0.645
USH2A	O75445-1.3	K481A	Neutral	0.231
USH2A	O75445-1.3	K481C	Pathogenic	0.801
USH2A	O75445-1.3	K481D	Neutral	0.275
USH2A	O75445-1.3	K481E	Neutral	0.122
USH2A	O75445-1.3	K481F	Pathogenic	0.967
USH2A	O75445-1.3	K481G	Neutral	0.242
USH2A	O75445-1.3	K481H	Pathogenic	0.586
USH2A	O75445-1.3	K481I	Pathogenic	0.954
USH2A	O75445-1.3	K481L	Pathogenic	0.895
USH2A	O75445-1.3	K481M	Pathogenic	0.748
USH2A	O75445-1.3	K481N	Neutral	0.175
USH2A	O75445-1.3	K481P	Neutral	0.435
USH2A	O75445-1.3	K481Q	Neutral	0.167
USH2A	O75445-1.3	K481R	Neutral	0.072
USH2A	O75445-1.3	K481S	Neutral	0.118
USH2A	O75445-1.3	K481T	Neutral	0.403
USH2A	O75445-1.3	K481V	Pathogenic	0.785
USH2A	O75445-1.3	K481W	Pathogenic	0.937
USH2A	O75445-1.3	K481Y	Pathogenic	0.874
USH2A	O75445-1.3	A482C	Pathogenic	0.886
USH2A	O75445-1.3	A482D	Pathogenic	0.977
USH2A	O75445-1.3	A482E	Pathogenic	0.907
USH2A	O75445-1.3	A482F	Pathogenic	0.926
USH2A	O75445-1.3	A482G	Pathogenic	0.867
USH2A	O75445-1.3	A482H	Pathogenic	0.919
USH2A	O75445-1.3	A482I	Pathogenic	0.888
USH2A	O75445-1.3	A482K	Pathogenic	0.834
USH2A	O75445-1.3	A482L	Pathogenic	0.882
USH2A	O75445-1.3	A482M	Pathogenic	0.856
USH2A	O75445-1.3	A482N	Pathogenic	0.971
USH2A	O75445-1.3	A482P	Pathogenic	0.932
USH2A	O75445-1.3	A482Q	Pathogenic	0.871
USH2A	O75445-1.3	A482R	Pathogenic	0.769
USH2A	O75445-1.3	A482S	Pathogenic	0.815
USH2A	O75445-1.3	A482T	Pathogenic	0.82
USH2A	O75445-1.3	A482V	Pathogenic	0.826
USH2A	O75445-1.3	A482W	Pathogenic	0.936
USH2A	O75445-1.3	A482Y	Pathogenic	0.873
USH2A	O75445-1.3	T483A	Neutral	0.247
USH2A	O75445-1.3	T483C	Pathogenic	0.658
USH2A	O75445-1.3	T483D	Pathogenic	0.724
USH2A	O75445-1.3	T483E	Pathogenic	0.611
USH2A	O75445-1.3	T483F	Pathogenic	0.681
USH2A	O75445-1.3	T483G	Pathogenic	0.507
USH2A	O75445-1.3	T483H	Pathogenic	0.647
USH2A	O75445-1.3	T483I	Pathogenic	0.572
USH2A	O75445-1.3	T483K	Neutral	0.448
USH2A	O75445-1.3	T483L	Pathogenic	0.56
USH2A	O75445-1.3	T483M	Pathogenic	0.502
USH2A	O75445-1.3	T483N	Pathogenic	0.506
USH2A	O75445-1.3	T483P	Pathogenic	0.658
USH2A	O75445-1.3	T483Q	Pathogenic	0.52
USH2A	O75445-1.3	T483R	Neutral	0.35
USH2A	O75445-1.3	T483S	Neutral	0.164
USH2A	O75445-1.3	T483V	Neutral	0.446
USH2A	O75445-1.3	T483W	Pathogenic	0.522
USH2A	O75445-1.3	T483Y	Pathogenic	0.538
USH2A	O75445-1.3	Q484A	Pathogenic	0.669
USH2A	O75445-1.3	Q484C	Pathogenic	0.964
USH2A	O75445-1.3	Q484D	Pathogenic	0.659
USH2A	O75445-1.3	Q484E	Neutral	0.382
USH2A	O75445-1.3	Q484F	Pathogenic	0.981
USH2A	O75445-1.3	Q484G	Pathogenic	0.683
USH2A	O75445-1.3	Q484H	Pathogenic	0.763
USH2A	O75445-1.3	Q484I	Pathogenic	0.986
USH2A	O75445-1.3	Q484K	Pathogenic	0.502
USH2A	O75445-1.3	Q484L	Pathogenic	0.968
USH2A	O75445-1.3	Q484M	Pathogenic	0.821
USH2A	O75445-1.3	Q484N	Pathogenic	0.676
USH2A	O75445-1.3	Q484P	Pathogenic	0.838
USH2A	O75445-1.3	Q484R	Neutral	0.401
USH2A	O75445-1.3	Q484S	Neutral	0.475
USH2A	O75445-1.3	Q484T	Pathogenic	0.819
USH2A	O75445-1.3	Q484V	Pathogenic	0.961
USH2A	O75445-1.3	Q484W	Pathogenic	0.919
USH2A	O75445-1.3	Q484Y	Pathogenic	0.842
USH2A	O75445-1.3	I485A	Neutral	0.39
USH2A	O75445-1.3	I485C	Neutral	0.457
USH2A	O75445-1.3	I485D	Pathogenic	0.925
USH2A	O75445-1.3	I485E	Pathogenic	0.954
USH2A	O75445-1.3	I485F	Neutral	0.37
USH2A	O75445-1.3	I485G	Pathogenic	0.828
USH2A	O75445-1.3	I485H	Pathogenic	0.949
USH2A	O75445-1.3	I485K	Pathogenic	0.965
USH2A	O75445-1.3	I485L	Neutral	0.144
USH2A	O75445-1.3	I485M	Neutral	0.326
USH2A	O75445-1.3	I485N	Pathogenic	0.93
USH2A	O75445-1.3	I485P	Pathogenic	0.851
USH2A	O75445-1.3	I485Q	Pathogenic	0.951
USH2A	O75445-1.3	I485R	Pathogenic	0.949
USH2A	O75445-1.3	I485S	Pathogenic	0.678
USH2A	O75445-1.3	I485T	Pathogenic	0.602
USH2A	O75445-1.3	I485V	Neutral	0.048
USH2A	O75445-1.3	I485W	Pathogenic	0.779
USH2A	O75445-1.3	I485Y	Pathogenic	0.626
USH2A	O75445-1.3	R486A	Pathogenic	0.815
USH2A	O75445-1.3	R486C	Pathogenic	0.983
USH2A	O75445-1.3	R486D	Pathogenic	0.927
USH2A	O75445-1.3	R486E	Pathogenic	0.823
USH2A	O75445-1.3	R486F	Pathogenic	0.998
USH2A	O75445-1.3	R486G	Pathogenic	0.824
USH2A	O75445-1.3	R486H	Pathogenic	0.901
USH2A	O75445-1.3	R486I	Pathogenic	0.997
USH2A	O75445-1.3	R486K	Pathogenic	0.633
USH2A	O75445-1.3	R486L	Pathogenic	0.992
USH2A	O75445-1.3	R486M	Pathogenic	0.978
USH2A	O75445-1.3	R486N	Pathogenic	0.757
USH2A	O75445-1.3	R486P	Pathogenic	0.963
USH2A	O75445-1.3	R486Q	Pathogenic	0.746
USH2A	O75445-1.3	R486S	Pathogenic	0.818
USH2A	O75445-1.3	R486T	Pathogenic	0.908
USH2A	O75445-1.3	R486V	Pathogenic	0.992
USH2A	O75445-1.3	R486W	Pathogenic	0.998
USH2A	O75445-1.3	R486Y	Pathogenic	0.993
USH2A	O75445-1.3	F487A	Neutral	0.17
USH2A	O75445-1.3	F487C	Neutral	0.212
USH2A	O75445-1.3	F487D	Pathogenic	0.633
USH2A	O75445-1.3	F487E	Pathogenic	0.742
USH2A	O75445-1.3	F487G	Neutral	0.228
USH2A	O75445-1.3	F487H	Neutral	0.335
USH2A	O75445-1.3	F487I	Neutral	0.106
USH2A	O75445-1.3	F487K	Pathogenic	0.888
USH2A	O75445-1.3	F487L	Neutral	0.109
USH2A	O75445-1.3	F487M	Neutral	0.134
USH2A	O75445-1.3	F487N	Pathogenic	0.651
USH2A	O75445-1.3	F487P	Pathogenic	0.646
USH2A	O75445-1.3	F487Q	Pathogenic	0.733
USH2A	O75445-1.3	F487R	Pathogenic	0.84
USH2A	O75445-1.3	F487S	Neutral	0.228
USH2A	O75445-1.3	F487T	Neutral	0.326
USH2A	O75445-1.3	F487V	Neutral	0.162
USH2A	O75445-1.3	F487W	Neutral	0.036
USH2A	O75445-1.3	F487Y	Neutral	0.017
USH2A	O75445-1.3	H488A	Pathogenic	0.927
USH2A	O75445-1.3	H488C	Pathogenic	0.987
USH2A	O75445-1.3	H488D	Pathogenic	0.945
USH2A	O75445-1.3	H488E	Pathogenic	0.927
USH2A	O75445-1.3	H488F	Pathogenic	0.972
USH2A	O75445-1.3	H488G	Pathogenic	0.871
USH2A	O75445-1.3	H488I	Pathogenic	0.996
USH2A	O75445-1.3	H488K	Pathogenic	0.964
USH2A	O75445-1.3	H488L	Pathogenic	0.996
USH2A	O75445-1.3	H488M	Pathogenic	0.988
USH2A	O75445-1.3	H488N	Pathogenic	0.782
USH2A	O75445-1.3	H488P	Pathogenic	0.97
USH2A	O75445-1.3	H488Q	Pathogenic	0.923
USH2A	O75445-1.3	H488R	Pathogenic	0.885
USH2A	O75445-1.3	H488S	Pathogenic	0.871
USH2A	O75445-1.3	H488T	Pathogenic	0.966
USH2A	O75445-1.3	H488V	Pathogenic	0.994
USH2A	O75445-1.3	H488W	Pathogenic	0.976
USH2A	O75445-1.3	H488Y	Pathogenic	0.614
USH2A	O75445-1.3	F489A	Neutral	0.353
USH2A	O75445-1.3	F489C	Neutral	0.418
USH2A	O75445-1.3	F489D	Pathogenic	0.822
USH2A	O75445-1.3	F489E	Pathogenic	0.885
USH2A	O75445-1.3	F489G	Neutral	0.441
USH2A	O75445-1.3	F489H	Pathogenic	0.573
USH2A	O75445-1.3	F489I	Neutral	0.24
USH2A	O75445-1.3	F489K	Pathogenic	0.955
USH2A	O75445-1.3	F489L	Neutral	0.247
USH2A	O75445-1.3	F489M	Neutral	0.292
USH2A	O75445-1.3	F489N	Pathogenic	0.833
USH2A	O75445-1.3	F489P	Pathogenic	0.829
USH2A	O75445-1.3	F489Q	Pathogenic	0.88
USH2A	O75445-1.3	F489R	Pathogenic	0.933
USH2A	O75445-1.3	F489S	Neutral	0.44
USH2A	O75445-1.3	F489T	Pathogenic	0.564
USH2A	O75445-1.3	F489V	Neutral	0.341
USH2A	O75445-1.3	F489W	Neutral	0.091
USH2A	O75445-1.3	F489Y	Neutral	0.045
USH2A	O75445-1.3	H490A	Neutral	0.089
USH2A	O75445-1.3	H490C	Neutral	0.366
USH2A	O75445-1.3	H490D	Neutral	0.118
USH2A	O75445-1.3	H490E	Neutral	0.089
USH2A	O75445-1.3	H490F	Neutral	0.211
USH2A	O75445-1.3	H490G	Neutral	0.05
USH2A	O75445-1.3	H490I	Pathogenic	0.667
USH2A	O75445-1.3	H490K	Neutral	0.17
USH2A	O75445-1.3	H490L	Pathogenic	0.655
USH2A	O75445-1.3	H490M	Neutral	0.397
USH2A	O75445-1.3	H490N	Neutral	0.027
USH2A	O75445-1.3	H490P	Neutral	0.201
USH2A	O75445-1.3	H490Q	Neutral	0.085
USH2A	O75445-1.3	H490R	Neutral	0.056
USH2A	O75445-1.3	H490S	Neutral	0.049
USH2A	O75445-1.3	H490T	Neutral	0.181
USH2A	O75445-1.3	H490V	Pathogenic	0.544
USH2A	O75445-1.3	H490W	Neutral	0.238
USH2A	O75445-1.3	H490Y	Neutral	0.012
USH2A	O75445-1.3	G491A	Pathogenic	0.838
USH2A	O75445-1.3	G491C	Pathogenic	0.979
USH2A	O75445-1.3	G491D	Pathogenic	0.873
USH2A	O75445-1.3	G491E	Pathogenic	0.892
USH2A	O75445-1.3	G491F	Pathogenic	0.935
USH2A	O75445-1.3	G491H	Pathogenic	0.828
USH2A	O75445-1.3	G491I	Pathogenic	0.979
USH2A	O75445-1.3	G491K	Pathogenic	0.81
USH2A	O75445-1.3	G491L	Pathogenic	0.978
USH2A	O75445-1.3	G491M	Pathogenic	0.94
USH2A	O75445-1.3	G491N	Pathogenic	0.702
USH2A	O75445-1.3	G491P	Pathogenic	0.941
USH2A	O75445-1.3	G491Q	Pathogenic	0.851
USH2A	O75445-1.3	G491R	Pathogenic	0.739
USH2A	O75445-1.3	G491S	Pathogenic	0.789
USH2A	O75445-1.3	G491T	Pathogenic	0.919
USH2A	O75445-1.3	G491V	Pathogenic	0.966
USH2A	O75445-1.3	G491W	Pathogenic	0.765
USH2A	O75445-1.3	G491Y	Pathogenic	0.888
USH2A	O75445-1.3	Q492A	Pathogenic	0.855
USH2A	O75445-1.3	Q492C	Pathogenic	0.987
USH2A	O75445-1.3	Q492D	Pathogenic	0.849
USH2A	O75445-1.3	Q492E	Pathogenic	0.643
USH2A	O75445-1.3	Q492F	Pathogenic	0.993
USH2A	O75445-1.3	Q492G	Pathogenic	0.862
USH2A	O75445-1.3	Q492H	Pathogenic	0.904
USH2A	O75445-1.3	Q492I	Pathogenic	0.995
USH2A	O75445-1.3	Q492K	Pathogenic	0.745
USH2A	O75445-1.3	Q492L	Pathogenic	0.989
USH2A	O75445-1.3	Q492M	Pathogenic	0.93
USH2A	O75445-1.3	Q492N	Pathogenic	0.859
USH2A	O75445-1.3	Q492P	Pathogenic	0.938
USH2A	O75445-1.3	Q492R	Pathogenic	0.66
USH2A	O75445-1.3	Q492S	Pathogenic	0.724
USH2A	O75445-1.3	Q492T	Pathogenic	0.93
USH2A	O75445-1.3	Q492V	Pathogenic	0.986
USH2A	O75445-1.3	Q492W	Pathogenic	0.971
USH2A	O75445-1.3	Q492Y	Pathogenic	0.939
USH2A	O75445-1.3	Y493A	Pathogenic	0.915
USH2A	O75445-1.3	Y493C	Pathogenic	0.935
USH2A	O75445-1.3	Y493D	Pathogenic	0.989
USH2A	O75445-1.3	Y493E	Pathogenic	0.985
USH2A	O75445-1.3	Y493F	Pathogenic	0.626
USH2A	O75445-1.3	Y493G	Pathogenic	0.939
USH2A	O75445-1.3	Y493H	Pathogenic	0.689
USH2A	O75445-1.3	Y493I	Pathogenic	0.97
USH2A	O75445-1.3	Y493K	Pathogenic	0.995
USH2A	O75445-1.3	Y493L	Pathogenic	0.968
USH2A	O75445-1.3	Y493M	Pathogenic	0.96
USH2A	O75445-1.3	Y493N	Pathogenic	0.977
USH2A	O75445-1.3	Y493P	Pathogenic	0.977
USH2A	O75445-1.3	Y493Q	Pathogenic	0.965
USH2A	O75445-1.3	Y493R	Pathogenic	0.994
USH2A	O75445-1.3	Y493S	Pathogenic	0.939
USH2A	O75445-1.3	Y493T	Pathogenic	0.962
USH2A	O75445-1.3	Y493V	Pathogenic	0.929
USH2A	O75445-1.3	Y493W	Pathogenic	0.742
USH2A	O75445-1.3	Y494A	Neutral	0.397
USH2A	O75445-1.3	Y494C	Neutral	0.47
USH2A	O75445-1.3	Y494D	Pathogenic	0.847
USH2A	O75445-1.3	Y494E	Pathogenic	0.802
USH2A	O75445-1.3	Y494F	Neutral	0.093
USH2A	O75445-1.3	Y494G	Neutral	0.488
USH2A	O75445-1.3	Y494H	Neutral	0.12
USH2A	O75445-1.3	Y494I	Pathogenic	0.664
USH2A	O75445-1.3	Y494K	Pathogenic	0.918
USH2A	O75445-1.3	Y494L	Pathogenic	0.653
USH2A	O75445-1.3	Y494M	Pathogenic	0.598
USH2A	O75445-1.3	Y494N	Pathogenic	0.724
USH2A	O75445-1.3	Y494P	Pathogenic	0.72
USH2A	O75445-1.3	Y494Q	Pathogenic	0.629
USH2A	O75445-1.3	Y494R	Pathogenic	0.916
USH2A	O75445-1.3	Y494S	Neutral	0.487
USH2A	O75445-1.3	Y494T	Pathogenic	0.609
USH2A	O75445-1.3	Y494V	Neutral	0.446
USH2A	O75445-1.3	Y494W	Neutral	0.15
USH2A	O75445-1.3	T495A	Neutral	0.431
USH2A	O75445-1.3	T495C	Pathogenic	0.816
USH2A	O75445-1.3	T495D	Pathogenic	0.858
USH2A	O75445-1.3	T495E	Pathogenic	0.784
USH2A	O75445-1.3	T495F	Pathogenic	0.831
USH2A	O75445-1.3	T495G	Pathogenic	0.704
USH2A	O75445-1.3	T495H	Pathogenic	0.809
USH2A	O75445-1.3	T495I	Pathogenic	0.756
USH2A	O75445-1.3	T495K	Pathogenic	0.652
USH2A	O75445-1.3	T495L	Pathogenic	0.746
USH2A	O75445-1.3	T495M	Pathogenic	0.7
USH2A	O75445-1.3	T495N	Pathogenic	0.703
USH2A	O75445-1.3	T495P	Pathogenic	0.816
USH2A	O75445-1.3	T495Q	Pathogenic	0.715
USH2A	O75445-1.3	T495R	Pathogenic	0.554
USH2A	O75445-1.3	T495S	Neutral	0.312
USH2A	O75445-1.3	T495V	Pathogenic	0.651
USH2A	O75445-1.3	T495W	Pathogenic	0.716
USH2A	O75445-1.3	T495Y	Pathogenic	0.729
USH2A	O75445-1.3	T496A	Neutral	0.014
USH2A	O75445-1.3	T496C	Neutral	0.078
USH2A	O75445-1.3	T496D	Neutral	0.103
USH2A	O75445-1.3	T496E	Neutral	0.064
USH2A	O75445-1.3	T496F	Neutral	0.085
USH2A	O75445-1.3	T496G	Neutral	0.043
USH2A	O75445-1.3	T496H	Neutral	0.074
USH2A	O75445-1.3	T496I	Neutral	0.055
USH2A	O75445-1.3	T496K	Neutral	0.034
USH2A	O75445-1.3	T496L	Neutral	0.053
USH2A	O75445-1.3	T496M	Neutral	0.042
USH2A	O75445-1.3	T496N	Neutral	0.043
USH2A	O75445-1.3	T496P	Neutral	0.078
USH2A	O75445-1.3	T496Q	Neutral	0.045
USH2A	O75445-1.3	T496R	Neutral	0.023
USH2A	O75445-1.3	T496S	Neutral	0.009
USH2A	O75445-1.3	T496V	Neutral	0.034
USH2A	O75445-1.3	T496W	Neutral	0.046
USH2A	O75445-1.3	T496Y	Neutral	0.049
USH2A	O75445-1.3	E497A	Neutral	0.148
USH2A	O75445-1.3	E497C	Pathogenic	0.842
USH2A	O75445-1.3	E497D	Neutral	0.021
USH2A	O75445-1.3	E497F	Pathogenic	0.759
USH2A	O75445-1.3	E497G	Neutral	0.156
USH2A	O75445-1.3	E497H	Neutral	0.167
USH2A	O75445-1.3	E497I	Pathogenic	0.819
USH2A	O75445-1.3	E497K	Neutral	0.04
USH2A	O75445-1.3	E497L	Pathogenic	0.811
USH2A	O75445-1.3	E497M	Pathogenic	0.599
USH2A	O75445-1.3	E497N	Neutral	0.109
USH2A	O75445-1.3	E497P	Neutral	0.308
USH2A	O75445-1.3	E497Q	Neutral	0.035
USH2A	O75445-1.3	E497R	Neutral	0.059
USH2A	O75445-1.3	E497S	Neutral	0.072
USH2A	O75445-1.3	E497T	Neutral	0.281
USH2A	O75445-1.3	E497V	Pathogenic	0.678
USH2A	O75445-1.3	E497W	Pathogenic	0.618
USH2A	O75445-1.3	E497Y	Neutral	0.43
USH2A	O75445-1.3	T498A	Neutral	0.006
USH2A	O75445-1.3	T498C	Neutral	0.032
USH2A	O75445-1.3	T498D	Neutral	0.044
USH2A	O75445-1.3	T498E	Neutral	0.027
USH2A	O75445-1.3	T498F	Neutral	0.036
USH2A	O75445-1.3	T498G	Neutral	0.018
USH2A	O75445-1.3	T498H	Neutral	0.031
USH2A	O75445-1.3	T498I	Neutral	0.023
USH2A	O75445-1.3	T498K	Neutral	0.014
USH2A	O75445-1.3	T498L	Neutral	0.022
USH2A	O75445-1.3	T498M	Neutral	0.017
USH2A	O75445-1.3	T498N	Neutral	0.018
USH2A	O75445-1.3	T498P	Neutral	0.032
USH2A	O75445-1.3	T498Q	Neutral	0.019
USH2A	O75445-1.3	T498R	Neutral	0.009
USH2A	O75445-1.3	T498S	Neutral	0.003
USH2A	O75445-1.3	T498V	Neutral	0.014
USH2A	O75445-1.3	T498W	Neutral	0.019
USH2A	O75445-1.3	T498Y	Neutral	0.02
USH2A	O75445-1.3	A499C	Neutral	0.003
USH2A	O75445-1.3	A499D	Neutral	0.018
USH2A	O75445-1.3	A499E	Neutral	0.004
USH2A	O75445-1.3	A499F	Neutral	0.005
USH2A	O75445-1.3	A499G	Neutral	0.003
USH2A	O75445-1.3	A499H	Neutral	0.005
USH2A	O75445-1.3	A499I	Neutral	0.003
USH2A	O75445-1.3	A499K	Neutral	0.002
USH2A	O75445-1.3	A499L	Neutral	0.003
USH2A	O75445-1.3	A499M	Neutral	0.003
USH2A	O75445-1.3	A499N	Neutral	0.014
USH2A	O75445-1.3	A499P	Neutral	0.006
USH2A	O75445-1.3	A499Q	Neutral	0.003
USH2A	O75445-1.3	A499R	Neutral	0.001
USH2A	O75445-1.3	A499S	Neutral	0.002
USH2A	O75445-1.3	A499T	Neutral	0.002
USH2A	O75445-1.3	A499V	Neutral	0.002
USH2A	O75445-1.3	A499W	Neutral	0.006
USH2A	O75445-1.3	A499Y	Neutral	0.003
USH2A	O75445-1.3	V500A	Neutral	0.327
USH2A	O75445-1.3	V500C	Pathogenic	0.594
USH2A	O75445-1.3	V500D	Pathogenic	0.955
USH2A	O75445-1.3	V500E	Pathogenic	0.924
USH2A	O75445-1.3	V500F	Pathogenic	0.549
USH2A	O75445-1.3	V500G	Pathogenic	0.786
USH2A	O75445-1.3	V500H	Pathogenic	0.934
USH2A	O75445-1.3	V500I	Neutral	0.06
USH2A	O75445-1.3	V500K	Pathogenic	0.862
USH2A	O75445-1.3	V500L	Neu